FLY_GENE SYMBOL FULL_NAME URL SECONDARY_FBGNS GENE_CLASS GO_MOLECULAR_FUNCTION GO_BIOLOGICAL_PROCESS GO_CELLULAR_COMPONENT SYNONYMS PROTEIN_DOMAINS CG_SYMBOL DATE_LAST_UPDATED DATA_VERSION ZEBRAFISH_ORTHOLOGS YEAST_ORTHOLOGS WORM_ORTHOLOGS XENOPUS_ORTHOLOGS MOUSE_ORTHOLOGS HUMAN_ORTHOLOGS RNA_EXPRESSION_STAGE RNA_EXPRESSION_TISSUE PROTEIN_EXPRESSION_STAGE PROTEIN_EXPRESSION_TISSUE FLYBASE_EXP_LINK PHENO_CLASS PHENO_MANIFEST DRSC SCREEN AVG_Z_SCORE_BASELINE_S2R AVG_Z_SCORE_10_INSULIN_S2R AVG_Z_SCORE_BASELINE_S2R_MTDER AVG_Z_SCORE_10_EGF_S2R_MTDER AVG_Z_SCORE_10_EGF_KC AVG_Z_SCORE_30_EGF_KC HUMAN_DISEASE HUMAN_ORTHOLOG_DESCRIPTION FBgn0026181 Rok Rho kinase http://flybase.net/reports/FBgn0026181.html FBgn0028698 protein_coding_gene "0017048=Rho GTPase binding, 0051020=GTPase binding, 0004674=protein serine/threonine kinase activity, 0005515=protein binding, 0005524=ATP binding, 0019992=diacylglycerol binding" "0051496=positive regulation of stress fiber assembly, 0030036=actin cytoskeleton organization, 0042067=establishment of ommatidial planar polarity, 0000281=mitotic cytokinesis, 0007266=Rho protein signal transduction, 0007302=nurse cell nucleus anchoring, 0001736=establishment of planar polarity, 0050770=regulation of axonogenesis, 0001737=establishment of imaginal disc-derived wing hair orientation, 0007300=ovarian nurse cell to oocyte transport, 0035317=imaginal disc-derived wing hair organization, 0045184=establishment of protein localization, 0006468=protein phosphorylation, 0007309=oocyte axis specification, 0008360=regulation of cell shape, 0003384=apical constriction involved in gastrulation, 0000022=mitotic spindle elongation, 0032231=regulation of actin filament bundle assembly, 0035191=nuclear axial expansion, 0042325=regulation of phosphorylation, 0008544=epidermis development, 0090303=positive regulation of wound healing, 1901739=regulation of myoblast fusion, 0032065=cortical protein anchoring, 0032956=regulation of actin cytoskeleton organization, 0048599=oocyte development, 1901888=regulation of cell junction assembly, 0007391=dorsal closure, 0016318=ommatidial rotation, 0001932=regulation of protein phosphorylation, 2000040=regulation of planar cell polarity pathway involved in axis elongation, 0008335=female germline ring canal stabilization, 0016331=morphogenesis of embryonic epithelium, 0031532=actin cytoskeleton reorganization, 0007067=mitotic nuclear division, 1903035=negative regulation of response to wounding" "0044291=cell-cell contact zone, 0045179=apical cortex" "dROK, unnamed, CG9774, Rho Kinase, Rhk, Rho-kinase, Rho-associated kinase, ROCK-1, RHO kinase, Drosophila rho-associated kinase, ROCK, ROCK2, RhoK, DROK, Rho-associated protein kinase, DRhk, rho kinase, DRok, Rock, dRok, rho-associated kinase, ROKalpha/beta, rok, ROK, Rok/ROCK, drok, RhoA kinase, ROCK1, Rho kinase, Drok, Rok, DRho-kinase" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR015008=Rho binding domain, IPR017441=Protein kinase, ATP binding site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR029875=Rho-associated protein kinase LET-502, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271=Serine/threonine-protein kinase, active site, IPR001849=Pleckstrin homology domain, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR020684=Rho-associated protein kinase 1/2" CG9774 16-Dec-15 2015_12 "ENSDARG00000017500(rock2a),ENSDARG00000004877(rock2b),ENSDARG00000058993" WBGene00002694(let-502) "ENSXETG00000023782(ROCK2),ENSXETG00000003151(ROCK1)" "ENSMUSG00000020580(Rock2),ENSMUSG00000024290(Rock1)" "ENSG00000067900(ROCK1),ENSG00000134318(ROCK2)" " embryonic stage , larval stage | third instar " "

ubiquitous , imaginal disc | ubiquitous

" "lethal - all die before end of pupal stage,visible,planar polarity defective,partially lethal - majority die,some die during pupal stage,wound healing defective,mitotic cell cycle defective,neuroanatomy defective,cell polarity defective,somatic clone,cell shape defective,increased cell death,wild-type,lethal,viable,recessive,female sterile,germline clone,axis specification defective,male limited,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic salivary gland,egg chamber,conditional,wing,mesothoracic tergum,S2 cell-line & spindle,S2 cell-line & cell,S2 cell-line & spindle microtubule,S2 cell-line & polar microtubule,embryonic/larval epidermis,oocyte,somatic clone,vertical lobe of adult mushroom body,nucleus,epithelial cell,eye,photoreceptor cell,crossvein,wing margin,macrophage | third instar larval stage,stress fiber | third instar larval stageHml.ëÓ,contractile ring | somatic clone,eye photoreceptor cell,supernumerary,ommatidium,wing hair,cell autonomous,mushroom body & axon | somatic clone,egg,germline clone,dorsal appendage,yolk granule | germline clone,nurse cell,nurse cell ring canal,filamentous actin & oocyte | germ-line clone,filamentous actin & nurse cell | germ-line clone,plasma membrane & oocyte | germ-line clone,hub cell,adherens junction | somatic clone,morphogenetic furrow,epithelium,follicle cell,anterior embryonic/larval midgut,male limited,embryonic proventriculus,embryonic/first instar larval cuticle,dorsal,dorsal hair,embryonic leading edge cell,wing disc | third instar larval stage,wing disc,somatic clone | third instar larval stage" DRSC20277 K 1.140488567 -0.484681497 -0.401458467 0.182061105 -0.607747052 -1.512870256 FBgn0000547 ed echinoid http://flybase.net/reports/FBgn0000547.html "FBgn0022256, FBgn0031582, FBgn0031583, FBgn0031584" protein_coding_gene 0005515=protein binding "0002009=morphogenesis of an epithelium, 0016319=mushroom body development, 0007423=sensory organ development, 0050768=negative regulation of neurogenesis, 0008360=regulation of cell shape, 0035331=negative regulation of hippo signaling, 0016337=single organismal cell-cell adhesion, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0035147=branch fusion, open tracheal system, 0032956=regulation of actin cytoskeleton organization, 0048644=muscle organ morphogenesis, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007391=dorsal closure, 0046621=negative regulation of organ growth, 0035330=regulation of hippo signaling, 0030038=contractile actin filament bundle assembly, 0007173=epidermal growth factor receptor signaling pathway, 0002121=inter-male aggressive behavior, 0046331=lateral inhibition, 0007476=imaginal disc-derived wing morphogenesis, 0035157=negative regulation of fusion cell fate specification, 0042060=wound healing, 0090138=regulation of actin cytoskeleton organization by cell-cell adhesion, 0046843=dorsal appendage formation" "0005886=plasma membrane, 0005938=cell cortex, 0005912=adherens junction, 0016021=integral component of membrane, 0005913=cell-cell adherens junction" "Echinoid, CG15424, CT13476, CT35484, E(Elp)24D, Ed, CG16842, CG12676, l(2)k01102, 1X5, E(Elp)[24D]" "IPR013162=CD80-like, immunoglobulin C2-set, IPR003961=Fibronectin type III, IPR013151=Immunoglobulin, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG12676 16-Dec-15 2015_12 WBGene00018215(igcm-1) "lethal,recessive,behavior defective,cell shape defective,cell autonomous,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,wild-type,viable,size defective,cell non-autonomous,wound healing defective,germline clone,cell adhesion defective" "embryonic/larval tracheal system,germline clone,rescuable maternal effect,embryo,embryonic epidermis,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,tracheal fusion cell,ectopic,wing disc,cell autonomous,somatic clone,cell non-autonomous,presumptive embryonic/larval central nervous system,embryonic neuroblast,embryonic/larval neuron,supernumerary,ventral nerve cord,macrochaeta,microchaeta,eye,wing vein L2,wing margin,distal,dorsocentral bristle,scutellar bristle,chemosensory ventral triple row & microchaeta | ectopic,dorsal triple row & microchaeta | ectopic,photoreceptor cell R8,sex comb,photoreceptor cell R7,wing,ommatidium,ommatidial precursor cluster,actomyosin | dorsal closure stagec381,epidermal cell | dorsal closure stage,eye photoreceptor cell,dorsal triple row & macrochaeta | ectopic,adult thorax & microchaeta | ectopic,embryonic/first instar larval cuticle,denticle belt,chorion | somatic clone,follicle cell,dorsal closure embryo,actin filament bundle | ectopic | somatic clone,adherens junction | somatic clone,embryonic leading edge cell & actomyosin,embryonic dorsal epidermis,embryonic segment,sensory mother cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,mystery cell,cone cell,wing vein,ventral longitudinal muscle,lateral transverse muscle,photoreceptor cell,apical plasma membrane & cell & dorsal mesothoracic disc & third instar larva | somatic clone,wing hair,wing cell,sensillum campaniformium & wing | supernumerary | somatic clone,oocyte,scutellum,dorsal appendage,actomyosin | dorsal closure stage,embryonic/larval dorsal anastomosis,posterior,chaeta,trichogen cell,mesothoracic tergum" DRSC00439 E -1.109723912 0.005681429 0.031203273 2.062307314 0.549157922 0.554889436 FBgn0030600 hiw highwire http://flybase.net/reports/FBgn0030600.html "FBgn0030604, FBgn0052592" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0005515=protein binding, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0030509=BMP signaling pathway, 0030514=negative regulation of BMP signaling pathway, 0006914=autophagy, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0040011=locomotion, 0007628=adult walking behavior, 0008582=regulation of synaptic growth at neuromuscular junction, 0050808=synapse organization, 0048678=response to axon injury, 2000331=regulation of terminal button organization" "0005886=plasma membrane, 0016023=cytoplasmic membrane-bounded vesicle" "CG32592, CG9041, Hiw, Highwire, CG9049" "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR014756=Immunoglobulin E-set, IPR004939=Anaphase-promoting complex, subunit 10/DOC domain, IPR008979=Galactose-binding domain-like, IPR001841=Zinc finger, RING-type, IPR012983=PHR, IPR013783=Immunoglobulin-like fold, IPR027047=E3 ubiquitin-protein ligase Highwire/Pam/Rpm-1, IPR017868=Filamin/ABP280 repeat-like" CG32592 16-Dec-15 2015_12 ENSDARG00000031417 "WBGene00004457(rpm-1),WBGene00017190(F07B7.12)" ENSMUSG00000033004(Mycbp2) ENSG00000005810(MYCBP2) "neuroanatomy defective,conditional,neurophysiology defective,somatic clone,decreased cell growth,recessive,locomotor behavior defective,viable" "embryonic/larval neuromuscular junction,NMJ bouton,supernumerary,synapse,neuromuscular junction | larval stage,dorsal multidendritic neuron ddaC,neuromuscular junction,indirect flight muscle motor neuron MN4,terminal bouton,segmental nerve,conditional,bouton,wing vein L1,somatic clone,terminal boutonelav.Switch.PO,neuromuscular junctionelav.Switch.PO,synapseelav.Switch.PO,indirect flight muscle motor neuron MN4 & bouton | ectopic,neuroblast,synaptic vesicle,motor neuron,giant fiber neuron,tergotrochanteral muscle motor neuron,synapseelav.Switch.PO, hiwëÓRCC1.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwëÓPHR.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwHindIII.UAS.TZzzzHis6,THsapMYC,synapseelav.Switch.PO, hiwëÓN.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwND8,eye" FBgn0003371 sgg shaggy http://flybase.net/reports/FBgn0003371.html "FBgn0026697, FBgn0026849, FBgn0027246, FBgn0028324, FBgn0029071, FBgn0066814" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0016301=kinase activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0051124=synaptic growth at neuromuscular junction, 0007622=rhythmic behavior, 0042752=regulation of circadian rhythm, 0042306=regulation of protein import into nucleus, 0007476=imaginal disc-derived wing morphogenesis, 0045879=negative regulation of smoothened signaling pathway, 0070884=regulation of calcineurin-NFAT signaling cascade, 0007350=blastoderm segmentation, 0008355=olfactory learning, 0043508=negative regulation of JUN kinase activity, 0007143=female meiotic division, 0045610=regulation of hemocyte differentiation, 0006355=regulation of transcription, DNA-templated, 0045732=positive regulation of protein catabolic process, 0009649=entrainment of circadian clock, 0030707=ovarian follicle cell development, 0046959=habituation, 0072347=response to anesthetic, 0016055=Wnt signaling pathway, 0030162=regulation of proteolysis, 0035293=chitin-based larval cuticle pattern formation, 0045475=locomotor rhythm, 0008407=chaeta morphogenesis, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0007219=Notch signaling pathway, 0007507=heart development, 0045842=positive regulation of mitotic metaphase/anaphase transition, 0007423=sensory organ development, 0048477=oogenesis, 0035019=somatic stem cell maintenance, 0007367=segment polarity determination, 0030178=negative regulation of Wnt signaling pathway, 0006468=protein phosphorylation, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0007623=circadian rhythm, 0003382=epithelial cell morphogenesis, 0007051=spindle organization, 0090163=establishment of epithelial cell planar polarity, 0035309=wing and notum subfield formation" "0045169=fusome, 0005654=nucleoplasm, 0005813=centrosome, 0072686=mitotic spindle, 0035324=female germline ring canal, 0005634=nucleus, 0005829=cytosol, 0005737=cytoplasm" "Sgg/Zw3/GSK3, Gsk-3beta, GSK-3, zestewhite-3, zw3/GSK3beta, Zw3-sh, anon-WO03040301.254, zeste white-3, CG2621, sgg-zw3, Shaggy/Zeste-white-3/Glycogen synthase kinase 3beta, zeste-white 3, GSK3-beta, zw3[sgg], Zeste-white3, Shaggy, SHAGGY, glycogen synthase kinase 3beta, Zeste-white 3, Zw3/GSK3, SGG/GSK3b, Saggy, GSK-3 kinase, Sgg/GSK-3b, GSK3beta/SGG, GSK-3B, zw3, GSK3A, DMZ3K25Z, DMSGG3, Shaggy/Glycogen synthase kinase 3, GSK-3betaSgg, l(1)3Ba, EG:155E2.3, shaggy/zeste-white 3, Dm Zw3, Gsk-3, Zw-3, zw-3, glycogen synthase kinase-3, shaggy/Glycogen Synthase Kinase 3, l(1)G0183, zeste-white3, Shaggy/GSK-3beta, Zw3[sgg], zw3/sgg, sgg/zw3, Glycogen Synthase Kinase 3, Dmsgg3, ZW-3, GSKbeta, GSK-3beta, l(1)G0263, zeste white 3, GSK3betagr;, Glycogen synthase kinase 3Beta, sgg10, sgg46, zw[3], gsk3, Zeste white-3, sgg39, Zw3, ZW3, l(1)zw3, Glycogen Synthase Kinase-3, l(1)G0335, shaggy-zeste white 3, zeste white3, l(1)G0055, GSK, zest-white 3, Sgg, EG:BACR7C10.8, GSK3, Gsk3, glycogen synthase kinase 3Beta, glycogen synthase kinase-3beta, SGG, GSK3beta, GSK3Beta, Zw3 kinase, zw3(sgg)" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG2621 16-Dec-15 2015_12 larval stage | third instar nerve terminal | subset

"lethal,recessive,visible,somatic clone,viable,locomotor rhythm defective,circadian rhythm defective,behavior defective,neuroanatomy defective,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,maternal effect,germline clone,developmental rate defective,mitotic cell cycle defective,planar polarity defective,cell non-autonomous,cell polarity defective,lethal - all die before end of embryonic stage,some die during embryonic stage,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,non-rescuable maternal effect,some die during third instar larval stage,meiotic cell cycle defective,short lived,smell perception defective,heat sensitive,fertile,chemical sensitive" "eye,somatic clone,eye disc,macrochaeta,supernumerary,synapse,macrochaeta & wing,embryonic/larval dorsal vessel,ommatidium,embryonic/first instar larval cuticle,germline clone,maternal effect,denticle belt,embryonic head,embryonic/larval spiracle,filzkorper,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval brain,wing,leg,tibia,tarsal segment,ventral thoracic disc,ventral thoracic disc & macrochaeta | somatic clone,syncytial blastoderm embryo,nucleus | embryonic stage 4 | germline clone,follicle stem cell,germline cyst,follicle cell,embryonic epidermis,dorsal,dorsal hair,embryonic Malpighian tubule,mesothoracic tarsal bristle longitudinal row 2,mesothoracic tarsal bristle longitudinal row 3,mesothoracic tarsal bristle longitudinal row 4,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 6,mesothoracic tarsal bristle longitudinal row 7,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,denticle,rescuable maternal effect,embryonic/larval somatic muscle,stomodeal invagination,midgut constriction 1,ectopic,posterior compartment,precursor,cell non-autonomous,wing margin bristle,wing vein,sensillum campaniformium,wing blade,mechanosensory ventral triple row bristle,wing sensillum,imaginal disc,egg,female reproductive system,wing hair,non-rescuable maternal effect,embryonic/larval neuromuscular junction,bouton,external sensory organ precursor cell,microchaeta,adult cuticle & abdomen | somatic clone,anterior,adult thorax & macrochaeta | somatic clone,adult thorax & microchaeta | somatic clone,cuticle,macrochaeta & wing | ectopic | somatic clone,1st axillary sclerite,2nd axillary sclerite,3rd axillary sclerite,unnamed wing hinge sclerite,axillary pouch,macrochaeta & mesothoracic tergum | somatic clone | cell autonomous,macrochaeta & scutum | somatic clone | cell autonomous,cell autonomous,macrochaeta & prescutum | somatic clone | cell autonomous,sensory mother cell,NMJ bouton,dendritic arborizing neuron | third instar larval stage,wing margin,mesothoracic tergum,morphogenetic furrow,melanotic mass,lamellocyte,crystal cell,scutellum,adult thorax & chaeta-537.4,dorsocentral bristle,posterior dorsocentral bristle,bouton | larval stage,scutellar bristle,wing disc,adult thorax & microchaeta-537.4,synapse796,antennal lobe,synapseGH298,intrinsic neuron,antennal lobe glomerulus DM2,synapseNP1227,synapsekra-krasavietz,synapseSxl-NP2426,synapseSxl-NP2426, kra-krasavietz,synapseTab2-201Y,adult mushroom body,eye | pharate adult stage,head | pharate adult stage,synapseD42,adult thorax,dorsal denticle,cuprophilic cell,midgut constriction 2,interommatidial bristle" FBgn0004101 bs blistered http://flybase.net/reports/FBgn0004101.html "FBgn0000156, FBgn0000223, FBgn0010354, FBgn0010535" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0033613=activating transcription factor binding, 0046983=protein dimerization activity, 0003677=DNA binding" "0035220=wing disc development, 0007614=short-term memory, 0045165=cell fate commitment, 0002168=instar larval development, 0008586=imaginal disc-derived wing vein morphogenesis, 0035209=pupal development, 0030154=cell differentiation, 0035154=terminal cell fate specification, open tracheal system, 0030431=sleep, 0007430=terminal branching, open tracheal system, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0007476=imaginal disc-derived wing morphogenesis, 0007424=open tracheal system development, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "Drosophila serum response factor, Serf, blistered/Drosophila serum response factor, CG3411, DSrf, bs/Dsrf, BS, Group IIc, balloon, Blistered, serum response factor, Pruned, ba, pruned/DSRF, DSRF, dsrf, dSRF, bs/DSRF, DmSRF, Serum response factor, l(2)03267, Serum Response Factor, srf, Srf, D-SRF, Drosophila Serum Response Factor, Bs, Mal, pruned, px, SRF, DSrf/bs, blistered/DSRF" "IPR002100=Transcription factor, MADS-box" CG3411 16-Dec-15 2015_12 "ENSDARG00000038131,ENSDARG00000053918(srf)" ENSMUSG00000015605(Srf) ENSG00000112658(SRF) " embryonic stage | >=stage 14 , embryonic stage | stage 16 , embryonic stage | stage >=14 " " abdominal segment 1--8

, embryonic/larval somatic muscle

, metathoracic segment | restricted

, embryonic central nervous system | restricted

, mesothoracic segment | restricted

, embryonic/larval midgut

, embryonic/larval hindgut

, pharyngeal muscle

" " embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage | >=stage 14 , pupal stage " " metathoracic segment | restricted

, mesothoracic segment | restricted

, embryonic/larval midgut

, embryonic/larval somatic muscle

, pharyngeal muscle

, abdominal segment 1--8

, embryonic/larval hindgut

, wing

, embryonic central nervous system | restricted

" "visible,recessive,viable,poor,fertile,semidominant,dominant,lethal,memory defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,somatic clone,wild-type,decreased cell size,cell autonomous,lethal - all die before end of pupal stage,some die during pupal stage,courtship behavior defective,locomotor behavior defective" "wing,wing vein,ectopic,trachea,wing cell,embryonic/larval tracheal system,somatic clone,tracheal metamere 3,wing vein L3 & sensillum campaniformium,sensillum campaniformium,wing & macrochaeta,macrochaeta,wing sensillum,tarsal segment,femur,rhabdomere,submarginal cell,wing disc,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,presumptive embryonic/larval tracheal system,cell non-autonomous,border follicle cell,follicle cell & actin filament | somatic clone,chaeta" FBgn0263977 Tim17b http://flybase.net/reports/FBgn0263977.html "FBgn0063894, FBan0040451, FBgn0067318" protein_coding_gene 0006626=protein targeting to mitochondrion 0005739=mitochondrion "CG40451, Tim17b" IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG40451 16-Dec-15 2015_12 "ENSDARG00000060124(timm17b),ENSDARG00000029510(timm17a)" YJL143W(TIM17) WBGene00017119(E04A4.5) ENSXETG00000007983(timm17a) "ENSMUSG00000062580(Timm17a),ENSMUSG00000031158(Timm17b)" "ENSG00000126768(TIMM17B),ENSG00000134375(TIMM17A)" "increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" mitochondrionunspecified FBgn0000233 btd buttonhead http://flybase.net/reports/FBgn0000233.html protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding, 0046872=metal ion binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007376=cephalic furrow formation, 0007480=imaginal disc-derived leg morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035288=anterior head segmentation, 0006357=regulation of transcription from RNA polymerase II promoter, 0007380=specification of segmental identity, head, 0035289=posterior head segmentation" 0005634=nucleus "button-head, BTD, Btd, CG12653" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG12653 16-Dec-15 2015_12 YMR070W(MOT3) WBGene00012735(sptf-3) " embryonic stage | embryonic cycle 12-14 , embryonic stage | blastoderm , embryonic stage | late , embryonic stage , embryonic stage | mid , embryonic stage | stage 3,4 , embryonic stage | stage 6,7 , embryonic stage | stage 5 , embryonic stage | stage 7-17 " " organism | 60-80% egg length

, embryonic intercalary segment | precursor

, ventral nerve cord | restricted

, embryonic deuterocerebrum | precursor

, embryonic mandibular segment | precursor

, organism | striped

, embryonic peripheral nervous system | restricted

, embryonic head | restricted

, cephalic furrow | anterior to

, leg | precursor

, organism | 70-80% egg length

, neuroblast

, procephalic neurogenic region | restricted

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,homeotic,somatic clone,viable" "papilla organ,antennal segment,mandibular segment,antenna,cephalopharyngeal skeleton,ventral,embryo,embryonic abdominal segment,embryonic head & sclerite | ectopic,embryonic head,embryonic mandibular segment,embryonic intercalary segment,embryonic antennal segment,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,cephalic furrow,associated organ,dorsolateral papilla,embryonic/larval optic lobe,antennal sense organ,lateropharyngeal organ,maxillary segment,anterior,scolopidium,deuterocerebral neuromere,tritocerebral neuromere,intercalary segment,anterior pharyngeal organ,Keilin's organ,embryonic Malpighian tubule,femur,somatic clone - Minute background,tibia,eye,ectopic,wing,haltere,leg,somatic clone,wing margin bristle,distal,proximal" FBgn0005626 ple pale http://flybase.net/reports/FBgn0005626.html "FBgn0003109, FBgn0003692" protein_coding_gene "0004511=tyrosine 3-monooxygenase activity, 0005506=iron ion binding" "0040040=thermosensory behavior, 0007619=courtship behavior, 0048066=developmental pigmentation, 0009072=aromatic amino acid family metabolic process, 0048085=adult chitin-containing cuticle pigmentation, 0043052=thermotaxis, 0055114=oxidation-reduction process, 0035220=wing disc development, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0006584=catecholamine metabolic process, 0042417=dopamine metabolic process, 2000274=regulation of epithelial cell migration, open tracheal system, 0008344=adult locomotory behavior, 0042416=dopamine biosynthetic process, 0042053=regulation of dopamine metabolic process, 0008049=male courtship behavior, 0009611=response to wounding, 0048067=cuticle pigmentation" "Drosophila tyrosine hydroxylase, tyrosine-hydroxylase, pale/ple, Pale, Ple, CG10118, tyrosine hydrodroxylase, DH65B, Tyrosone hydroxylase, dTH1, XBB70 Group VII, dTH65B, VII, Tyrosine Hydroxylase, pale, Th, TH, Tyrosine-3-hydroxylase, th, tyrosine hydroxylase, Tyrosine hydroxylase, DTH" "IPR019773=Tyrosine 3-monooxygenase-like, IPR005962=Tyrosine 3-monooxygenase, IPR019774=Aromatic amino acid hydroxylase, C-terminal, IPR001273=Aromatic amino acid hydroxylase, IPR018301=Aromatic amino acid hydroxylase, iron/copper binding site" CG10118 16-Dec-15 2015_12 "ENSDARG00000038384(th2),ENSDARG00000030621(th)" WBGene00000296(cat-2) "ENSXETG00000014030(TH),ENSXETG00000025926()" ENSMUSG00000000214(Th) ENSG00000180176(TH) " adult stage , larval stage && adult stage , larval stage | third instar , larval stage , larval stage | first instar " " adult abdomen

, adult brain

, central nervous system

, adult head

, adult thorax

, epidermis

, larval central nervous system

" "visual behavior defective,phototaxis defective,locomotor rhythm defective,sleep defective,hypoactive,smell perception defective,gravitaxis defective,wild-type,lethal,recessive,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,somatic clone,body color defective,thermotaxis behavior defective,dominant,locomotor behavior defective,courtship behavior defective,feeding behavior defective,long lived,drug conditional,memory defective,viable" "wing,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,adult cuticle,somatic clone,microchaeta,mouth hooks,cuticle,spiracle,macrochaeta,serotonergic neuron,wing cell,adult abdomen,adult thorax,dopaminergic neuron,drug conditional,mesothoracic tergum" DRSC11383 IEK 0.763470174 -1.621909565 -1.525471935 -2.188261945 -2.821184033 -3.427405512 FBgn0029157 ssh slingshot http://flybase.net/reports/FBgn0029157.html "FBgn0010740, FBgn0039253, FBgn0041200" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0003677=DNA binding, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0017017=MAP kinase tyrosine/serine/threonine phosphatase activity, 0008330=protein tyrosine/threonine phosphatase activity, 0003779=actin binding" "0016319=mushroom body development, 0050770=regulation of axonogenesis, 0006470=protein dephosphorylation, 0008064=regulation of actin polymerization or depolymerization, 0030036=actin cytoskeleton organization, 0048749=compound eye development, 0010591=regulation of lamellipodium assembly, 0000278=mitotic cell cycle" "0005856=cytoskeleton, 0005737=cytoplasm" "CG6238, MAP-kinase-phosphatase, MKP, MKP-like, Ssh, Slingshot, SSH, l(3)01207, Mkph" "IPR016130=Protein-tyrosine phosphatase, active site, IPR014876=DEK, C-terminal, IPR029021=Protein-tyrosine phosphatase-like, IPR027232=Protein phosphatase Slingshot, IPR000387=Tyrosine specific protein phosphatases domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR009057=Homeodomain-like, IPR024950=Dual specificity phosphatase, IPR020422=Dual specificity protein phosphatase domain" CG6238 16-Dec-15 2015_12 "ENSDARG00000010031(ssh1b),ENSDARG00000056780(ssh1a)" "ENSXETG00000017954(SSH2),ENSXETG00000022310(SSH1)" "ENSMUSG00000037926(Ssh2),ENSMUSG00000042121(Ssh1)" "ENSG00000141298(SSH2),ENSG00000084112(SSH1)" "lethal,recessive,visible,somatic clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "denticle belt,embryonic/first instar larval cuticle,eye,somatic clone,maternal effect,ommatidium,rhabdomere,adult mushroom body & axon | somatic clone,medial branch of mushroom body,optic lobe neuron & axon | somatic clone,antennal lobe & axon | somatic clone,vertical lobe of adult mushroom body,filamentous actin & ommatidial cluster | ectopic | somatic clone,nucleus & ommatidial cluster | somatic clone,apical junction complex & ommatidial cluster | somatic clone,wing hair,macrochaeta & mesothoracic tergum | somatic clone,actin filament | cell autonomous | ectopic | somatic clone,filamentous actin | somatic clone,medial lobe of adult mushroom body" DRSC16730 K 0.360154131 0.621323091 -0.0240727 0.206665041 1.815135056 1.285103886 FBgn0001961 Arpc1 "Actin-related protein 2/3 complex, subunit 1" http://flybase.net/reports/FBgn0001961.html protein_coding_gene "0005200=structural constituent of cytoskeleton, 0003779=actin binding" "0051491=positive regulation of filopodium assembly, 0030041=actin filament polymerization, 0001745=compound eye morphogenesis, 0030029=actin filament-based process, 0008407=chaeta morphogenesis, 0007293=germarium-derived egg chamber formation, 0030589=pseudocleavage involved in syncytial blastoderm formation, 0060429=epithelium development, 0006886=intracellular protein transport, 0030037=actin filament reorganization involved in cell cycle, 0034314=Arp2/3 complex-mediated actin nucleation, 0045747=positive regulation of Notch signaling pathway, 0022416=chaeta development, 0000902=cell morphogenesis, 0033627=cell adhesion mediated by integrin, 0007010=cytoskeleton organization, 0007413=axonal fasciculation, 0007409=axonogenesis" 0005885=Arp2/3 protein complex "ArpC1, br32, Sop2, Dsop2, 34Dd, ARC-P41, p41, sop, profilin 2, Suppressor of Profilin 2, l(2)34Dd, l(2)Sop2, Suppressor of, ARPC1/p41, Suppressor of profilin 2, ARPC1, p42, ArcP41, CG8978, DSop2, lethal(2)34Dd, Spo2, arpc1, Arc41, D-sop2, sop2, Arpc1, arc41, sop2/arc41, l(2)br32, BG:DS00941.7" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR017383=Actin-related protein 2/3 complex subunit 1" CG8978 16-Dec-15 2015_12 "ENSDARG00000008383(arpc1a),ENSDARG00000027063(arpc1b),ENSDARG00000040656(LOC100330051)" YBR234C(ARC40) WBGene00000201(arx-3) "ENSXETG00000006057(arpc1a),ENSXETG00000006058(),ENSXETG00000018292()" "ENSMUSG00000029621(Arpc1a),ENSMUSG00000029622(Arpc1b),ENSMUSG00000046993(Gm5637)" "ENSG00000013455,ENSG00000130429(ARPC1B)" oogenesis stage | stage S9 ring canal

"lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,supernumerary,mesothoracic tergum,nurse cell,germline clone,follicle cell,somatic clone,epithelium,female germline cyst,filopodium,nurse cell ring canal,actin filament & nurse cell | germ-line clone,nucleus & nurse cell | germ-line clone,tormogen cell,macrochaeta,eye,ommatidium,lens,interommatidial bristle,macrochaeta & adult head | somatic clone,microchaeta & adult head | somatic clone,rhabdomere | adult stage | somatic clone,photoreceptor,retina,cell cycle | germline clone,metaphase & condensed nuclear chromosome | germ-line clone,centrosome | ectopic | germline clone,actin filament | germline clone,oocyte,nucleus | embryonic stage 4 | germline clone | non-rescuable maternal effect,actin filament | embryonic stage 4 | germline clone | non-rescuable maternal effect,nurse cell & actin filament | germ-line clone,anterior dorsocentral bristle,myoblast,mechanosensory chaeta,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,wing" FBgn0020510 Abi Abelson interacting protein http://flybase.net/reports/FBgn0020510.html protein_coding_gene "0004871=signal transducer activity, 0005515=protein binding" "0030866=cortical actin cytoskeleton organization, 0006909=phagocytosis, 0048846=axon extension involved in axon guidance, 0032956=regulation of actin cytoskeleton organization, 0007030=Golgi organization, 0008360=regulation of cell shape, 0048477=oogenesis, 0051495=positive regulation of cytoskeleton organization, 0030032=lamellipodium assembly, 0033627=cell adhesion mediated by integrin, 0045860=positive regulation of protein kinase activity, 0021955=central nervous system neuron axonogenesis, 0000902=cell morphogenesis, 0030036=actin cytoskeleton organization, 0007528=neuromuscular junction development, 0072499=photoreceptor cell axon guidance, 0016203=muscle attachment, 0007155=cell adhesion, 0022416=chaeta development, 0030031=cell projection assembly" "0048471=perinuclear region of cytoplasm, 0031209=SCAR complex, 0031258=lamellipodium membrane, 0043234=protein complex, 0045178=basal part of cell" "Abelson interactor, Abi-1, CG9749, Abelson Interacting Protein, abi, dAbi, Ablphilin" "IPR012849=Abl-interactor, homeo-domain homologous domain, IPR001452=SH3 domain, IPR028457=ABI family" CG9749 16-Dec-15 2015_12 "ENSDARG00000014875(zgc:136560),ENSDARG00000058207(zgc:153663),ENSDARG00000010155(abi1a),ENSDARG00000062991(abi1b)" WBGene00015146(abi-1) "ENSXETG00000004155(abi2),ENSXETG00000018784(abi1)" "ENSMUSG00000026782(Abi2),ENSMUSG00000058835(Abi1)" "ENSG00000138443(ABI2),ENSG00000136754(ABI1)" "neuroanatomy defective,recessive,lethal - all die before end of P-stage,some die during P-stage,visible,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of embryonic stage,germline clone,some die during embryonic stage,cell shape defective,viable" "outer photoreceptor cell,tract,lamina,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,somatic clone,dorsocentral bristle,scutellar bristle,chaeta,sensory mother cell,longitudinal connective,maternal effect,filamentous actin | ectopicen-e16E,notopleural bristle,supernumerary,chaeta & mesothoracic tergum | ectopic-537.4,presumptive embryonic/larval nervous system" DRSC14099 K -0.025477939 -0.365066553 -0.494653164 -0.285618757 1.813661836 0.138283321 FBgn0020416 Idgf1 Imaginal disc growth factor 1 http://flybase.net/reports/FBgn0020416.html FBgn0027915 protein_coding_gene "0008084=imaginal disc growth factor receptor binding, 0004568=chitinase activity" "0007444=imaginal disc development, 0005975=carbohydrate metabolic process, 0006032=chitin catabolic process" 0005576=extracellular region "IDGF-1, CG4472, IDGF1, IDGF, ldgf1, idgf1, BG:DS02780.5, Imaginal disc growth factor1, DmIDGF1" "IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain, IPR011583=Chitinase II, IPR015520=Imaginal disc growth factor, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain" CG4472 16-Dec-15 2015_12 " embryonic stage , larval stage | third instar , adult stage && oogenesis stage , embryonic stage && larval stage , embryonic stage&&larval stage " " yolk

, larval brain

, imaginal disc

, oocyte

, ventral furrow | vicinity of

, amnioproctodeal invagination | vicinity of

, nurse cell

, ring gland

, cephalic furrow | vicinity of

, larval optic lobe

, lymph gland

, embryonic/larval tracheal system

, embryonic/larval salivary gland

, embryonic/larval fat body

" viable DRSC03349 E -0.39789249 0.113950392 -1.664635496 0.59493807 -0.16923865 -0.150656505 FBgn0003888 ë_Tub60D ë_-Tubulin at 60D http://flybase.net/reports/FBgn0003888.html protein_coding_gene "0003924=GTPase activity, 0005200=structural constituent of cytoskeleton, 0005525=GTP binding" "0007507=heart development, 0009416=response to light stimulus, 0022008=neurogenesis, 0007409=axonogenesis, 0007411=axon guidance, 0007017=microtubule-based process, 0030537=larval behavior, 0051258=protein polymerization" "0005874=microtubule, 0045298=tubulin complex" "beta3tub, beta3TUB, beta-3-tubulin, tubulin b-3, p53, Dmbeta3, b3 Tubulin, beta3 tubulin, beta-Tubulin, beta-3 Tubulin, Tub60D, 60C beta tubulin, p50/tubulin, 143391_i_at, beta 3 tubulin, b-3 tubulin, Beta3 tubulin, beta[[3]]-Tub, beta-3tubulin, beta-Tub6D, beta3-tubulin, beta3t, beta3, B3-tubulin, beta-Tubulin at 60D, beta-tub, T, betaTub60D, beta[[3]] tubulin, beta60C, beta-tubulin60D, Tub, D.m.BETA-60D, beta3tubulin, beta[[3]]-tubulin, betaTub, DTB3, 3t, tubulin, beta-tubulin, BETA 60D, p53/tubulin, beta tubulin, beta-Tubulin at 60A, beta3-Tub, p50, beta3Tub, beta-3 tubulin, beta-tubulin at 60D, betaTub3, Beta tubulin, beta-tubulin 60D, CG3401, beta-Tub60D, betatub60D, B3t, beta3 TU, beta3-Tubulin, betaTub60C" "IPR003008=Tubulin/FtsZ, GTPase domain, IPR023123=Tubulin, C-terminal, IPR013838=Beta tubulin, autoregulation binding site, IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR000217=Tubulin, IPR002453=Beta tubulin" CG3401 16-Dec-15 2015_12 YFL037W(TUB2) " embryonic stage | stage 13 , embryonic stage | 0-10 hr , prepupal stage , larval stage | third instar , pupal stage | mid , oogenesis stage && adult stage | female , embryonic stage | stage 12 , embryonic stage | 9-15 hr , pupal stage , oogenesis stage && pupal stage , embryonic stage | stage 14 , embryonic stage | >=stage 11 , embryonic stage | stage 10 , adult stage | male , pupal stage | mid-late " " visceral mesoderm

, ventral metathoracic disc

, indirect flight muscle

, follicle cell

, mesoderm

, ovary

, head mesoderm

, dorsal metathoracic disc

, dorsal mesothoracic disc

, optic lobe | presumptive

, somatic mesoderm

, adult brain | presumptive

, testis | cyst cell

, muscle system

, eye-antennal disc

, testis

, ventral mesothoracic disc

, ventral prothoracic disc

" embryonic stage | stage 17 mesoderm | posterior | segmentally repeated pattern

"viable,sterile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,recessive,partially lethal - majority die,male fertile,fertile,flightless,phototaxis defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,visible,male sterile,neuroanatomy defective,some die during pupal stage,locomotor behavior defective" "axoneme,meiotic cell cycle | male,embryonic/larval midgut,chordotonal organ & microtubulePx2),optic lobe,eye,lamina,medulla & axon,photoreceptor cell R8 & axon,photoreceptor cell R7 & axon,rhabdomere,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,tormogen cell,mesothoracic tergum" FBgn0001297 kay kayak http://flybase.net/reports/FBgn0001297.html "FBgn0053956, FBgn0000468, FBgn0000725, FBgn0003506, FBgn0039693, FBtr0085478, FBpp0084844, FBtr0085479, FBpp0084845, FBtr0085480, FBpp0084846" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0070491=repressing transcription factor binding, 0005515=protein binding" "0045475=locomotor rhythm, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development, 0007297=ovarian follicle cell migration, 0007254=JNK cascade, 0019730=antimicrobial humoral response, 0009611=response to wounding, 0007281=germ cell development, 0046529=imaginal disc fusion, thorax closure, 0042060=wound healing, 0048674=collateral sprouting of injured axon, 0051124=synaptic growth at neuromuscular junction, 0001736=establishment of planar polarity, 0048813=dendrite morphogenesis, 0031660=regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle, 0016330=second mitotic wave involved in compound eye morphogenesis, 0007391=dorsal closure, 0035220=wing disc development, 0007464=R3/R4 cell fate commitment, 0007298=border follicle cell migration" "0005737=cytoplasm, 0005634=nucleus, 0005667=transcription factor complex" "AP1, dlhD, Fra, DM3, CG33956, dorsal holes D, KAY, Kay, fbz, Dfos, CG15507, d-fos, DFOS, fos, c-Fos, activator protein 1, dAP-1, Fos-related antigen, DFos, D-fos/kay, Fos, dfos, Dfos/kayak, D-Fos, fra, dFos, AP-1, dFRA, FOS, Kayak, c-fos, dFra, CG15509, DFra, D-fos, DM30" "IPR004827=Basic-leucine zipper domain, IPR000837=AP-1 transcription factor" CG33956 16-Dec-15 2015_12 "ENSDARG00000031683(fos),ENSDARG00000040135(LOC570238),ENSDARG00000007776,ENSDARG00000040623(LOC100331923),ENSDARG00000015355(fosl1),ENSDARG00000055751(zgc:92354)" WBGene00001345(fos-1) " embryonic stage | stage 15 , embryonic stage , embryonic stage | 4-8 hr " " eo neuron

, dorsal ectoderm

, embryonic/larval midgut

, muscle attachment site

, amnioserosa

, embryonic/larval hindgut

, anal pad

, multidendritic neuron

, embryonic peripheral nervous system | restricted

, head | restricted

" "neuroanatomy defective,locomotor rhythm defective,viable,fertile,planar polarity defective,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,wild-type,lethal,wound healing defective,cell lethalcell lethal,heat sensitive,neurophysiology defective,conditional,partially,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,increased cell death,developmental rate defective,long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" "Kenyon cell,axoney-OK107,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,ommatidium,photoreceptor cell R4,somatic clone,embryonic/larval hemocyte | third instar larval stage,dendrite,RP2 motor neuron,eye photoreceptor cell,egg,maternal effect,dorsal appendage,nurse cell & nucleus | somatic clone,stage S14 oocyte,adult thorax,dorsal,mesothoracic cleft,embryonic dorsal epidermis,dorsal closure embryo,embryonic epidermis,embryonic head,embryo,wing disc,wing,embryonic ventral epidermis,follicle cell,stage S9 oocyte,embryonic/first instar larval cuticle,wing vein L3,wing vein L5,wing vein,heart primordium,scutellum,imaginal disc,pupal thorax,salivary gland,eye,cuprophilic cell,midgut interstitial cell,adult midgut precursor cell,bouton,neuromuscular junction | larval stage,terminal bouton,synapse,anterior crossvein,wing vein L2,wing vein L4,neuromuscular junctionBG380,segmental nerve,conditional,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,motor neuron,thorax,pigment cell,trichogen cell,mesothoracic tergum,adult heart,RU486 conditional,posterior" DRSC16977 IE 3.022447147 4.211683207 2.840500332 1.748045363 -0.463202103 -0.167621605 FBgn0038167 Lkb1 Lkb1 kinase http://flybase.net/reports/FBgn0038167.html "FBgn0027757, FBgn0045844" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0072697=protein localization to cell cortex, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 0046328=regulation of JNK cascade, 0007163=establishment or maintenance of cell polarity, 0030709=border follicle cell delamination, 0043065=positive regulation of apoptotic process, 0007391=dorsal closure, 0045451=pole plasm oskar mRNA localization, 0055059=asymmetric neuroblast division, 0045201=maintenance of neuroblast polarity, 0007052=mitotic spindle organization, 0016325=oocyte microtubule cytoskeleton organization" "0005634=nucleus, 0005737=cytoplasm, 0005938=cell cortex" "anon-EST:Posey135, PAR-4, dLKB1, Lkb1, PAR4, lkb1, LKB1, LKB1/PEUTZ JEGHERS KINASE, CG9374, STK11, DmLKB1, dlkb1, par-4" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR020636=Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG9374 16-Dec-15 2015_12 ENSDARG00000046074(zgc:110180) WBGene00003919(par-4) ENSXETG00000003285(stk11) ENSMUSG00000003068(Stk11) ENSG00000118046(STK11) "hyperplasia,long lived,female limited,heat sensitive,cell polarity defective,mitotic cell cycle defective,decreased cell death,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,lethal,recessive,germline clone,maternal effect,cell cycle defective,cytokinesis defective" "wing,eye,embryonic/larval brain,ventral nerve cord,wing disc,wing blade,follicle cell,oocyte,germline clone,oocyte & microtubule | germ-line clone,border follicle cell,somatic clone,neuroblast,spindle,centrosome,brain,aster,kinetochore microtubule,spindle microtubule,spindleurd),asterurd),kinetochore microtubuleurd),spindle microtubuleurd),spindle & larval neuroblasturd),embryonic/larval neuroblast,centrosome & larval neuroblasturd),scutellum,adult thoracic sensillum" FBgn0015858 anon-14Ab anon-14Ab http://flybase.net/reports/FBgn0015858.html gene td28 16-Dec-15 2015_12 FBgn0011661 Moe Moesin http://flybase.net/reports/FBgn0011661.html "FBgn0013950, FBgn0014345, FBgn0026689, FBgn0027218, FBgn0028282, FBgn0028289, FBgn0066841, FBgn0066842, FBgn0066843, FBgn0066844" protein_coding_gene "0008092=cytoskeletal protein binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding, 0003779=actin binding, 0005515=protein binding" "0007315=pole plasm assembly, 0035149=lumen formation, open tracheal system, 0045433=male courtship behavior, veined wing generated song production, 0002009=morphogenesis of an epithelium, 0042048=olfactory behavior, 0030036=actin cytoskeleton organization, 0042052=rhabdomere development, 0007368=determination of left/right symmetry, 0032956=regulation of actin cytoskeleton organization, 0008104=protein localization, 0008284=positive regulation of cell proliferation, 0030866=cortical actin cytoskeleton organization, 0030029=actin filament-based process, 0045313=rhabdomere membrane biogenesis, 0000912=assembly of actomyosin apparatus involved in cytokinesis, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0042462=eye photoreceptor cell development, 0051653=spindle localization, 0016336=establishment or maintenance of polarity of larval imaginal disc epithelium, 0009952=anterior/posterior pattern specification, 0007052=mitotic spindle organization, 0007318=pole plasm protein localization, 0007314=oocyte anterior/posterior axis specification, 0072499=photoreceptor cell axon guidance, 0033109=cortical actin cytoskeleton stabilization, 0000902=cell morphogenesis, 0016057=regulation of membrane potential in photoreceptor cell, 0000132=establishment of mitotic spindle orientation, 0007091=metaphase/anaphase transition of mitotic cell cycle, 0035088=establishment or maintenance of apical/basal cell polarity, 0045807=positive regulation of endocytosis, 0007010=cytoskeleton organization" "0016324=apical plasma membrane, 0005912=adherens junction, 0045169=fusome, 0005938=cell cortex, 0005886=plasma membrane, 0005884=actin filament, 0032154=cleavage furrow, 1990023=mitotic spindle midzone, 0019898=extrinsic component of membrane, 0005737=cytoplasm, 0015629=actin cytoskeleton, 0005634=nucleus, 0005819=spindle, 0035003=subapical complex" "DMoesin, Emr1, moesin, gma, CG10701, Ezrin-Radixin-Moesin, anon-WO03040301.161, Dmoe, EMR1, l(1)G0415, Moesin-like, anon-WO03040301.157, Dmoesin, moesin/ezrin/radixin homolog mRNA, l(1)G0323, Ezrin-moesin-radixin-1, l(1)G0067, Moes, D17, ERM, dMoe, anon-WO03040301.159, anon-WO03040301.155, moe, dMoesin, l(1)G0404" "IPR011259=Ezrin/radixin/moesin, C-terminal, IPR000299=FERM domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749=Band 4.1 domain, IPR008954=Moesin tail domain, IPR000798=Ezrin/radixin/moesin-like, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019748=FERM central domain, IPR011174=Ezrin/radixin/moesin, IPR018980=FERM, C-terminal PH-like domain, IPR019747=FERM conserved site, IPR018979=FERM, N-terminal, IPR029071=Ubiquitin-related domain" CG10701 16-Dec-15 2015_12 "ENSDARG00000025091(ezr),ENSDARG00000020944(ezrl),ENSDARG00000028740,ENSDARG00000058128(rdx)" WBGene00001333(erm-1) "ENSXETG00000009770(vil2),ENSXETG00000009776(Q5BJ89_XENTR)" "ENSMUSG00000031207(Msn),ENSMUSG00000032050(Rdx),ENSMUSG00000052397(Ezr)" "ENSG00000147065(MSN),ENSG00000137710(RDX),ENSG00000092820(EZR)" pupal stage mesothoracic bristle

"viable,smell perception defective,increased cell death,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,somatic clone,song defective,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,developmental rate defective,recessive,size defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,male,female,fertile" "rhabdomere & actin filament, with MoedsRNA.327-775.UAS, hs.PB,rhabdomere & actin filament, with MoedsRNA.327-775.UAS, GMR.PF,photoreceptor cell,wing vein,wing,wing disc,wing hinge,rhabdomere & actin filament, with MoedsRNA.818-1326.UAS, hs.PB,rhabdomere & actin filament, with MoedsRNA.818-1326.UAS, GMR.PF,spindleC587,cyst progenitor cell,wing disc | third instar larval stage,1st posterior cell,wing blade,eye,somatic clone | third instar larval stage,germline cell,wing vein L3,rhabdomere & microvillushs.PB,rhabdomere & plasma membrane | apicalhs.PB,rhabdomere & cytoskeleton | apicalhs.PB,lamina plexus | third instar larval stage,medulla | third instar larval stage,oocyte & cytoskeleton[-],germline cell | embryonic stage,oocyte & cytoskeleton,imaginal disc,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,somatic clone,lamina plexus,embryonic abdominal segment,non-rescuable maternal effect,embryonic/first instar larval cuticle,pole cell,rhabdomere & plasma membrane | apical | somatic clone,rhabdomere & actin filament | somatic clone,basal lamina & dorsal mesothoracic disc & third instar larva,ommatidium,oocyte & actin filament,nurse cell & actin filament,embryonic/larval midgut primordium,embryonic hindgut,presumptive embryonic salivary gland,retina,dorsal trunk primordium,oocyte & actin filament | ectopicnos.UTR.THsimVP16,nurse cell & actin filamentnos.UTR.THsimVP16,nurse cell & actin filamentMoe-PG26,cell non-autonomous | third instar larval stage,cell autonomous | third instar larval stage" FBgn0013733 shot short stop http://flybase.net/reports/FBgn0013733.html "FBgn0014183, FBgn0015972, FBgn0020296, FBgn0021837, FBgn0021937, FBgn0022152, FBgn0022170, FBgn0022208, FBgn0022230" protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding, 0005515=protein binding, 0008092=cytoskeletal protein binding, 0008017=microtubule binding" "0007026=negative regulation of microtubule depolymerization, 0007409=axonogenesis, 0045773=positive regulation of axon extension, 0035147=branch fusion, open tracheal system, 0048813=dendrite morphogenesis, 0016203=muscle attachment, 0016204=determination of muscle attachment site, 0035149=lumen formation, open tracheal system, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0007424=open tracheal system development, 0000226=microtubule cytoskeleton organization, 0030036=actin cytoskeleton organization, 0030716=oocyte fate determination, 0007517=muscle organ development, 0007050=cell cycle arrest, 0001578=microtubule bundle formation, 0016199=axon midline choice point recognition, 0007017=microtubule-based process, 0030516=regulation of axon extension, 0016319=mushroom body development, 0007423=sensory organ development, 0051491=positive regulation of filopodium assembly" "0035371=microtubule plus-end, 0005856=cytoskeleton, 0030426=growth cone, 0005927=muscle tendon junction, 0005737=cytoplasm, 0000235=astral microtubule, 0005874=microtubule, 0030175=filopodium, 0045169=fusome, 0005912=adherens junction, 0044295=axonal growth cone" "CG18637, l(2)k15606, Spectraplakin, 42/4, groovin, Short stop, l(2)k10821, CG18076, l(2)k03010, kakapoo, kopupu, Kakapo, shortstop, l(2)k05821, shortshop, Shortstop, Shot, short-stop, Grv, l(2)CA4, kak, l(2)k04204, shortstop/kakapo, l(2)k05434, Short Stop, grv, kakapo, Su(Mir)1, unnamed, kop" "IPR002048=EF-hand domain, IPR002017=Spectrin repeat, IPR001452=SH3 domain, IPR001715=Calponin homology domain, IPR018247=EF-Hand 1, calcium-binding site, IPR018159=Spectrin/alpha-actinin, IPR011992=EF-hand domain pair, IPR001101=Plectin repeat, IPR003108=Growth-arrest-specific protein 2 domain, IPR001589=Actinin-type actin-binding domain, conserved site" CG18076 16-Dec-15 2015_12 ENSDARG00000062590(si:dkey-151c10.1) WBGene00006876(vab-10) ENSXETG00000007367(MACF1) "ENSMUSG00000026131(Dst),ENSMUSG00000028649(Macf1)" "ENSG00000151914(LOC100652766),ENSG00000127603(MACF1)" " embryonic stage , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage 16 " " muscle attachment site

, embryonic peripheral nervous system

, epidermis

, embryonic central nervous system

, organism | segmentally repeated

" " embryonic stage | stage 16 , larval stage | third instar , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage 12-17 " " embryonic/larval proventriculus

, tendon cell

, scolopidium

, sensory neuron

, muscle attachment site

, epidermis

, chordotonal organ

, neuron

, embryonic/larval pharynx

, intersegmental nerve

" "lethal,recessive,neuroanatomy defective,paralytic,lethal - all die before end of embryonic stage,some die during embryonic stage,decreased cell number,somatic clone,germline clone,visible,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,chordotonal organ,lateral,scolopidial dendrite,extended germ band embryo,dorsal closure embryo,embryonic epidermis,dendrite & motor neuron | embryonic stage,axon & motor neuron | embryonic stage,neuron,microtubuleMK1),dendrite | dorsal | embryonic stage,presumptive embryonic/larval peripheral nervous system,dorsal,NMJ bouton,supernumerary,supernumerary | third instar larval stage,segmental nerve,RP3 motor neuron,embryonic/larval somatic muscle,embryonic/first instar larval cuticle,muscle attachment site,neuromuscular junction | embryonic stage,embryonic/larval mushroom body,somatic clone,lateral trunk primordium,intersegmental nerve,oocyte,egg chamber & follicle cell | somatic clone,mushroom body & axon,synapse & neuromuscular junction,chordotonal organ & axon | lateral,longitudinal connective,sensory neuron,ovary,germline clone,nurse cell,ectopic,microtubule & ovary | germ-line clone,centrosome & ovary | germ-line clone,axon & pCC neuron,abdominal segmental nerve,embryonic/larval dorsal anastomosis,dorsal trunk primordium,calyx of adult mushroom body,axonMK1),filopodiumMK1),wing,larva,proventriculus inner layer primordium,proventriculus intermediate layer primordium,embryonic proventriculus,embryonic/larval motor neuron,tendon cell,synapse & neuromuscular junctionMK1),RP1 motor neuron,tendon cell & actin filamenthow-24B, sr-md710,tendon cell & microtubulehow-24B, sr-md710" DRSC05459 IE -0.036086644 -3.390270537 -0.954132705 -4.143168369 -1.290758851 -1.384957247 FBgn0003093 Pkc98E Protein C kinase 98E http://flybase.net/reports/FBgn0003093.html FBgn0005692 protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0019992=diacylglycerol binding, 0004697=protein kinase C activity, 0004698=calcium-dependent protein kinase C activity" "0009950=dorsal/ventral axis specification, 0008285=negative regulation of cell proliferation, 0007252=I-kappaB phosphorylation, 0045471=response to ethanol, 0007616=long-term memory, 0034389=lipid particle organization, 0048812=neuron projection morphogenesis, 0090277=positive regulation of peptide hormone secretion, 0007030=Golgi organization, 0040018=positive regulation of multicellular organism growth, 0006468=protein phosphorylation" 0005886=plasma membrane "PKC-98F, PKC98E, protein kinase C, 98F, PKC d98F, PKC-brain, PKC 98F, PK-C, nPKC, PKCdelta, dPKC98F, Nc98F, Dpkc3, PKC98C, PKC, Protein kinase-c3, Pkc3, Neural-conserved-at-98F, CG1954" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000008=C2 domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR014376=Protein kinase C, delta/epsilon/eta/theta types, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR020454=Diacylglycerol/phorbol-ester binding, IPR017892=Protein kinase, C-terminal" CG1954 16-Dec-15 2015_12 ENSDARG00000003008(prkcea) YBL105C(PKC1) WBGene00004032(pkc-1) ENSXETG00000022951(PRKCE) "ENSMUSG00000045038(Prkce),ENSMUSG00000021108(Prkch)" "ENSG00000171132(PRKCE),ENSG00000027075(PRKCH)" " larval stage | second instar , larval stage | third instar , embryonic stage , adult stage , larval stage | first instar , pupal stage " " cell body &&of adult brain

, head

" "chemical resistant,neuroanatomy defective,memory defective,viable" "denticle,ectopic,filzkorper,embryonic head,embryonic/first instar larval cuticle,embryonic/larval central nervous system" FBgn0003499 sr stripe http://flybase.net/reports/FBgn0003499.html "FBgn0010828, FBgn0026215" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0007517=muscle organ development, 0006909=phagocytosis, 0007390=germ-band shortening, 0016204=determination of muscle attachment site, 0007427=epithelial cell migration, open tracheal system, 0007398=ectoderm development, 0007525=somatic muscle development, 0006355=regulation of transcription, DNA-templated, 0042440=pigment metabolic process, 0007417=central nervous system development" 0005634=nucleus "Stripe, stripe, SrB, Striped, l(3)03999, CG7847, l(3)06948, StripeB, Sr, STRIPE, l(3)06948b" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG7847 16-Dec-15 2015_12 YKL062W(MSN4) " embryonic stage , embryonic stage | stage >=14 , embryonic stage && pupal stage " " muscle attachment site

, epidermis | restricted

" embryonic stage " epidermis | restricted

, muscle attachment site

" "lethal,recessive,viable,visible,flightless,lethal - all die before end of embryonic stage,some die during embryonic stage,cell shape defective,partially lethal - majority die,some die during pupal stage,eye color defective" "thorax,skeletal muscle of abdomen,adult muscle system,dorsal medial muscle,macrochaeta,somatic mesoderm,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,embryonic/larval ganglionic branch,embryonic/larval muscle system,embryonic/larval visceral branch,lch5 cap attachment cell,lch5 ligament attachment cell,muscle fiber,muscle attachment site,embryonic/larval somatic muscle,embryonic/larval tracheal system,adult thorax,mesothoracic tergum & microchaetasr-md710,mesothoracic tergum & chaeta-C253,ventral,lateral transverse muscle | embryonic stage,abdominal 5 ventral longitudinal muscle | embryonic stage,abdominal 6 ventral longitudinal muscle | embryonic stage,abdominal 7 ventral longitudinal muscle | embryonic stage,abdominal 5 lateral transverse muscle | embryonic stage,abdominal 6 lateral transverse muscle | embryonic stage,abdominal 7 lateral transverse muscle | embryonic stage,embryonic somatic muscle,lateral,somatic muscle | embryonic stage,supernumerary,germ band,ectoderm,mesothoracic tergum" FBgn0029891 Pink1 PTEN-induced putative kinase 1 http://flybase.net/reports/FBgn0029891.html FBgn0046284 protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding, 0005515=protein binding" "0035234=ectopic germ cell programmed cell death, 0006468=protein phosphorylation, 0030382=sperm mitochondrion organization, 0010821=regulation of mitochondrion organization, 0090141=positive regulation of mitochondrial fission, 0043524=negative regulation of neuron apoptotic process, 0048749=compound eye development, 0007005=mitochondrion organization, 0006979=response to oxidative stress, 0043069=negative regulation of programmed cell death, 0010637=negative regulation of mitochondrial fusion, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 1902956=regulation of mitochondrial electron transport, NADH to ubiquinone, 0007274=neuromuscular synaptic transmission, 0000266=mitochondrial fission, 0000422=mitochondrion degradation" "0005737=cytoplasm, 0016006=Nebenkern, 0005739=mitochondrion" "CG4523, PTEN-Induced Kinase 1, PTEN-induced Putative Kinase 1, phosphatase and tensin homolog-induced putative kinase 1, BEST:GH23468, PTEN induced putative kinase 1, PINK, PINK1, dPink1, Pink1, PTEN-induced kinase 1, dPINK1, pink1" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site" CG4523 16-Dec-15 2015_12 "ENSDARG00000030423,ENSDARG00000001929(pink1)" WBGene00017137(pink-1) ENSMUSG00000028756(Pink1) ENSG00000158828(PINK1) "visible,neuroanatomy defective,increased cell size,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile,progressive,sterile,chemical sensitive,osmotic stress response defective,male sterile,locomotor behavior defective,short lived,increased cell death,flightless,flight defective,heat stress response defective,smell perception defective,neurophysiology defective,recessive,gravitaxis defective,female sterile,partially" "eye,dopamine neuron & adult brainelav.PLu,ommatidium,dopamine neuron & adult brainDdc.PL,interommatidial bristle,pigment cell,photoreceptor & neuronGMR.PF,spermatid,Nebenkern,mitochondrial derivative,dopaminergic neuron,progressive,indirect flight muscle,mitochondrion,mitochondrial crista,mitochondrial crista & indirect flight muscle,minor mitochondrial derivative,wing,depressor muscle,myofibrilda.G32,mitochondrial cristada.G32,mitochondrionMhc.PW,myofibrilMhc.PW,mitochondrial cristaMhc.PW,mitochondrion & dorso-lateral dopaminergic neuronple.PF,adult thorax,mitochondrion & dopaminergic neuron,mitochondrion & indirect flight muscle,mitochondrial inner membrane & indirect flight muscle,mitochondrion & dorso-lateral dopaminergic neuron,dopaminergic PPL1 neuron,dopaminergic PPM1 neuron,dopaminergic PPM2 neuron,neuron,adult somatic muscle,mitochondrial outer membrane,adult antennal lobe,bouton,flight muscle,embryonic/larval neuromuscular junction,synaptic vesicle,spermatozoon,mitochondrial outer membrane & indirect flight muscle,myofibril & indirect flight muscle,dopamine neuron & adult brain,mitochondrion & dopamine neuron & adult brain,thorax,skeletal muscle of thorax,dorso-lateral dopaminergic neuron,Nebenkern derivative,spermatid cyst,eye | adult stage,ommatidium | adult stage" FBgn0039294 Cad96Cb Cadherin 96Cb http://flybase.net/reports/FBgn0039294.html "FBan0010421, FBgn0039295" protein_coding_gene 0005509=calcium ion binding "0007424=open tracheal system development, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0044331=cell-cell adhesion mediated by cadherin, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "cad96Cb, CT29262, cg13664, CG13664, cad96C, Cad96C, DCad96Cb, Cad96Cb, CG10421" "IPR020894=Cadherin conserved site, IPR015919=Cadherin-like, IPR002126=Cadherin" CG13664 16-Dec-15 2015_12 "ENSDARG00000037691(pcdh2ab2),ENSDARG00000045665,ENSDARG00000005808,ENSDARG00000058909(pcdh2ab12),ENSDARG00000037705(pcdh2ab5),ENSDARG00000071905,ENSDARG00000071904,ENSDARG00000069239,ENSDARG00000069238,ENSDARG00000069233,ENSDARG00000069234,ENSDARG00000069231,ENSDARG00000043961,ENSDARG00000054274(pcdh10a),ENSDARG00000036121(pcdh10b),ENSDARG00000037697,ENSDARG00000071889,ENSDARG00000071895,ENSDARG00000071898,ENSDARG00000071892,ENSDARG00000071890,ENSDARG00000010684,ENSDARG00000071900,ENSDARG00000071896,ENSDARG00000071894,ENSDARG00000071893,ENSDARG00000037698,ENSDARG00000071899,ENSDARG00000071901,ENSDARG00000058941(pcdh2g28),ENSDARG00000071891,ENSDARG00000062610,ENSDARG00000057519,ENSDARG00000071903,ENSDARG00000037700,ENSDARG00000067675,ENSDARG00000071902,ENSDARG00000037699,ENSDARG00000069223,ENSDARG00000062608(pcdh1g2),ENSDARG00000037682,ENSDARG00000043953,ENSDARG00000071897,ENSDARG00000043951,ENSDARG00000043959,ENSDARG00000067674(pcdh1g3),ENSDARG00000037695(pcdh2aa1),ENSDARG00000057514,ENSDARG00000069224,ENSDARG00000027041,ENSDARG00000034344(pcdh19),ENSDARG00000006467(pcdh8),ENSDARG00000017868,ENSDARG00000052494(pcdh18b),ENSDARG00000042586(LOC100002026),ENSDARG00000063264,ENSDARG00000036424,ENSDARG00000036175,ENSDARG00000062720,ENSDARG00000058935,ENSDARG00000058875(pcdh2ab11),ENSDARG00000052650,ENSDARG00000060610(LOC555504),ENSDARG00000057773" WBGene00000401(cdh-9) "ENSXETG00000022978(FAT4),ENSXETG00000013565(PCDH17),ENSXETG00000027155(),ENSXETG00000003663(PCDH10),ENSXETG00000025040(),ENSXETG00000027159(),ENSXETG00000027157(),ENSXETG00000004170(),ENSXETG00000008295(),ENSXETG00000006527(),ENSXETG00000016119(),ENSXETG00000024520(),ENSXETG00000024519(),ENSXETG00000016123(),ENSXETG00000018865(),ENSXETG00000024521(),ENSXETG00000024518(),ENSXETG00000027152(),ENSXETG00000015402(),ENSXETG00000024522(),ENSXETG00000003735(),ENSXETG00000027062(),ENSXETG00000022436()" "ENSMUSG00000047033(Pcdhb15),ENSMUSG00000048347(Pcdhb18),ENSMUSG00000045498(Pcdhb3),ENSMUSG00000044043(Pcdhb14),ENSMUSG00000051599(Pcdhb2),ENSMUSG00000073591(Pcdhb22),ENSMUSG00000063687(Pcdhb5),ENSMUSG00000045062(Pcdhb7),ENSMUSG00000051242(Pcdhb9),ENSMUSG00000046387(Pcdhb17),ENSMUSG00000045689(Pcdhb4),ENSMUSG00000047910(Pcdhb16),ENSMUSG00000051486(Pcdhb11),ENSMUSG00000045657(Pcdhb10),ENSMUSG00000047307(Pcdhb13),ENSMUSG00000043458(Pcdhb12),ENSMUSG00000043313(Pcdhb19),ENSMUSG00000051678(Pcdhb6),ENSMUSG00000044022(Pcdhb21),ENSMUSG00000045876(Pcdhb8),ENSMUSG00000051663(Pcdhb1),ENSMUSG00000069394,ENSMUSG00000023036(Pcdhg@),ENSMUSG00000007440(Pcdhac2),ENSMUSG00000049100,ENSMUSG00000079714,ENSMUSG00000051323(Pcdh19),ENSMUSG00000035566(Pcdh17),ENSMUSG00000037892(Pcdh18),ENSMUSG00000036422(Pcdh8),ENSMUSG00000024440(Pcdh12),ENSMUSG00000051375(Pcdh1),ENSMUSG00000055421(Pcdh9),ENSMUSG00000029108(Pcdh7),ENSMUSG00000050505(Pcdh20)" "ENSG00000171815(PCDHB1),ENSG00000196963(PCDHB16),ENSG00000113205(PCDHB3),ENSG00000112852(PCDHB2),ENSG00000113212(PCDHB7),ENSG00000113248(PCDHB15),ENSG00000187372(PCDHB13),ENSG00000120322(PCDHB8),ENSG00000081818(PCDHB4),ENSG00000120327(PCDHB14),ENSG00000113209(PCDHB5),ENSG00000120328(PCDHB12),ENSG00000113211(PCDHB6),ENSG00000120324(PCDHB10),ENSG00000197479(PCDHB11),ENSG00000146001,ENSG00000204956(PCDHGA1),ENSG00000214567,ENSG00000214580,ENSG00000081842(PCDHA6),ENSG00000214574,ENSG00000204955,ENSG00000214594,ENSG00000214570,ENSG00000138650(PCDH10),ENSG00000214583,ENSG00000204968,ENSG00000204969(PCDHA2),ENSG00000204970(PCDHA1),ENSG00000214608,ENSG00000081853(PCDHGA2),ENSG00000204967(PCDHA4),ENSG00000204963(PCDHA7),ENSG00000204961(PCDHA9),ENSG00000214600,ENSG00000204962(PCDHA8),ENSG00000204965(PCDHA5),ENSG00000204964,ENSG00000113555(PCDH12),ENSG00000156453(PCDH1),ENSG00000184226(PCDH9),ENSG00000197991(PCDH20)" "viable,partially lethal - majority die,some die during pupal stage" FBgn0026479 Drp1 Dynamin related protein 1 http://flybase.net/reports/FBgn0026479.html "FBgn0005566, FBgn0005579, FBgn0031438, FBgn0042649" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0030382=sperm mitochondrion organization, 0090141=positive regulation of mitochondrial fission, 0000281=mitotic cytokinesis, 0048312=intracellular distribution of mitochondria, 0016050=vesicle organization, 0016185=synaptic vesicle budding from presynaptic membrane, 0090140=regulation of mitochondrial fission, 0007005=mitochondrion organization, 0007370=ventral furrow formation, 0051646=mitochondrion localization" 0005875=microtubule associated complex "dynaminrelated protein 1, noodle, Drp-1, near dpp complementation group 3, dynamin-related protein 1, drp-1, DRP1, DRP, dynamin-related protein, Noodle, near dpp complementation group 2, lethal(2)22Fc, dynamin-2, dynamin related protein-1, drp1, l(2)22Fc, lethal(2)22Fd, Drp, Dynamin Related Protein 1, CG3210, fratboy, Dnm1/Drp1, l(2)ND2, frat, l(2)22Fd, unnamed, l(2)ND3" "IPR001401=Dynamin, GTPase domain, IPR030381=Dynamin-type guanine nucleotide-binding (G) domain, IPR003130=Dynamin GTPase effector, IPR019762=Dynamin, GTPase region, conserved site, IPR020850=GTPase effector domain, GED, IPR022812=Dynamin superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000375=Dynamin central domain" CG3210 16-Dec-15 2015_12 "ENSDARG00000015006(dnm1l),ENSDARG00000063159(si:dkey-32e23.4)" YLL001W(DNM1) WBGene00001093(drp-1) ENSXETG00000012252(DNM1L) ENSMUSG00000022789(Dnm1l) ENSG00000087470(DNM1L) "neurophysiology defective,lethal,recessive,viable,visible" "mitochondrion,Nebenkern,mitochondrionMef2.PR,mitochondrion & primary spermatocyte | germ-line clone,Nebenkern | germline clone,mitochondrial derivative | germline clone,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,ventral furrow,mitochondrion & larval salivary gland,mitochondrion & bouton,mitochondrion & larval nervous system,mitochondrion & motor neuron,embryonic/larval neuromuscular junction,trichogen cell" DRSC00574 K 1.078866981 -0.158466985 -0.040794711 -0.18690649 1.710953056 0.227550084 FBgn0033550 CG12341 http://flybase.net/reports/FBgn0033550.html FBgn0062871 protein_coding_gene BcDNA:SD17342 IPR019334=Transmembrane protein 170 CG12341 16-Dec-15 2015_12 ENSDARG00000071205 WBGene00009673(F43G9.13) ENSXETG00000004702(TMEM170A) ENSMUSG00000031953(Tmem170) ENSG00000166822(TMEM170A) viable FBgn0005630 lola longitudinals lacking http://flybase.net/reports/FBgn0005630.html "FBgn0010468, FBgn0010691, FBgn0012046, FBgn0020247, FBgn0026589, FBgn0033530, FBgn0033531, FBgn0033532, FBgn0033533, FBgn0033534, FBgn0033535, FBgn0045396, FBgn0045853, FBgn0050012, FBgn0050013, FBgn0050014, FBgn0063156, FBgn0064821" protein_coding_gene "0046872=metal ion binding, 0005515=protein binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0007409=axonogenesis, 0007464=R3/R4 cell fate commitment, 0048813=dendrite morphogenesis, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 0035167=larval lymph gland hemopoiesis, 0045893=positive regulation of transcription, DNA-templated, 0007526=larval somatic muscle development, 0019730=antimicrobial humoral response, 0007411=axon guidance, 0002121=inter-male aggressive behavior, 0006357=regulation of transcription from RNA polymerase II promoter, 0016199=axon midline choice point recognition, 0008406=gonad development, 0048854=brain morphogenesis, 0044719=regulation of imaginal disc-derived wing size, 0045467=R7 cell development, 0045476=nurse cell apoptotic process" "0005634=nucleus, 0005654=nucleoplasm" "sw59, BTB-IV, LD03274, BcDNA:RH31485, misguided, Longitudinals lacking, CG12052, e, BEST:LD03274, SGP cluster fusion defects 7, CG18376, l(2)00642, CG30012, BTB-protein-IV, CG18379, eyeful, Lola, CG18378, longitudinals-lacking, CG18381, lola, l(2)s3697, longitudinals absent, NEST:bs06a08, BtbIV, fus7, BcDNA:LD17006, CG30013, longitudinal lacking, CG30014, CG18380, bs06a08.y1" "IPR007087=Zinc finger, C2H2, IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR011333=POZ domain" CG12052 16-Dec-15 2015_12 ENSXETG00000021232() "ENSG00000181722(ZBTB20),ENSG00000119574(ZBTB45)" " embryonic stage | stage 12-17 , embryonic stage | stage >12 , embryonic stage | stage 1-15 , embryonic stage | stage >=10 , embryonic stage | stage 12-14 , embryonic stage | stage 10,11 , embryonic stage | stage 16-17 " " central nervous system

, histoblast

, organism

, mesoderm

, imaginal disc | presumptive

, embryonic peripheral nervous system

, mesectoderm

, embryonic optic lobe primordium

" " embryonic stage , larval stage | third instar , embryonic stage | stage 1-17 , embryonic stage | stage 1-13 , adult stage " " epithelial cell

, embryonic/larval somatic muscle

, central nervous system

, embryonic peripheral nervous system

, tracheocyte

, organism

, organism

" "neuroanatomy defective,courtship behavior defective,male,somatic clone,lethal,recessive,partially lethal - majority die,viable,fertile,behavior defective,visible,wild-type,partially,heat sensitive,some die during pupal stage,body color defective,size defective" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,dendrite & adult antennal lobe projection neuron | somatic cloneGH146,axon & adult antennal lobe projection neuron | somatic cloneGH146,adult antennal lobe projection neuron,somatic clone,adult antennal lobe projection neuron DA1 vPN,adult antennal lobe projection neuron VA1v vPN,adult antennal lobe projection neuron adPN,adult antennal lobe projection neuron lPN,adult antennal lobe projection neuron DL1 adPN,lateral horn,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lolae76,axon & adult antennal lobe projection neuron | somatic cloneGH146, lolae76,longitudinal connective,intersegmental nerve,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,abdominal segmental nerve,commissure,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,abdominal intersegmental nerve,abdominal 1 lateral monoscolopidial chordotonal organ lch1,abdominal 2 lateral monoscolopidial chordotonal organ lch1,abdominal 3 lateral monoscolopidial chordotonal organ lch1,abdominal 4 lateral monoscolopidial chordotonal organ lch1,abdominal 5 lateral monoscolopidial chordotonal organ lch1,abdominal 6 lateral monoscolopidial chordotonal organ lch1,abdominal 7 lateral monoscolopidial chordotonal organ lch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,VUM neuron,central nervous system,nurse cell,germline clone,egg chamber,axon & adult antennal lobe projection neuron | somatic clone,dendrite & adult antennal lobe projection neuron | somatic clone,macrochaeta,dorsocentral bristle,scutellar bristle,tormogen cell,gonad,gonadal sheath proper primordium,arista,eye,axon,antennal lobe projection neuron adPN,cell autonomous,antennal lobe projection neuron vPN,antennal lobe projection neuron lPN,dendrite & larval antennal lobe projection neuron | somatic clone | penetrance incomplete | expressivity incomplete | cell autonomous,axon & larval antennal lobe projection neuron | somatic clone | penetrance incomplete | expressivity incomplete | cell autonomous,adult mushroom body,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lola3.8.UAS,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lola4.7.UAS,axon & adult antennal lobe projection neuron | somatic cloneGH146, lola4.7.UAS,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lolaL.UAS,axon & adult antennal lobe projection neuron | somatic cloneGH146, lolaL.UAS,ventral longitudinal muscle,presumptive embryonic/larval central nervous system,dorsal appendage,synapsehow-24B,synapsetwi.PG,dendrite & adult antennal lobe projection neuron | somatic clone | heat sensitiveGH146,axon & adult antennal lobe projection neuron | somatic clone | heat sensitiveGH146,heat sensitive,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum,ganglion mother cell,wing,posterior" DRSC27862 IEK 0.725057073 -1.799942145 5.589401193 -1.538656754 1.43490837 1.608543358 FBgn0085106 l(3)S068808 l(3)S068808 http://flybase.net/reports/FBgn0085106.html gene 16-Dec-15 2015_12 FBgn0061134 l(3)S001901 lethal (3) S001901 http://flybase.net/reports/FBgn0061134.html gene 0019/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0069234 gl(2L)159-23 gl(2L)159-23 http://flybase.net/reports/FBgn0069234.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive" FBgn0264651 loose-caboose loose caboose http://flybase.net/reports/FBgn0264651.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "embryonic/larval dorsal branch 10,embryonic/larval tracheal system,eye,somatic clone" FBgn0039379 CG5886 http://flybase.net/reports/FBgn0039379.html protein_coding_gene 0019905=syntaxin binding IPR026183=Taxilin family CG5886 16-Dec-15 2015_12 "ENSDARG00000070468,ENSDARG00000001969(txlng)" WBGene00011917(T22C1.6) "ENSXETG00000005241(TXLNA),ENSXETG00000001109(),ENSXETG00000011669(TXLNB)" "ENSMUSG00000053841(Txlna),ENSMUSG00000038344(Txlng),ENSMUSG00000039891(Txlnb)" "ENSG00000084652(TXLNA),ENSG00000086712(TXLNG),ENSG00000164440(TXLNB)" viable FBgn0023520 CG3857 http://flybase.net/reports/FBgn0023520.html protein_coding_gene "0042332=gravitaxis, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 0005622=intracellular EG:39E1.3 IPR027417=P-loop containing nucleoside triphosphate hydrolase CG3857 16-Dec-15 2015_12 ENSXETG00000004098(C19orf61) ENSMUSG00000002210(1500002O20Rik) ENSG00000105771(SMG9) "gravitaxis defective,viable,lethal" FBgn0051439 Muc96D Mucin 96D http://flybase.net/reports/FBgn0051439.html protein_coding_gene "0008061=chitin binding, 0005201=extracellular matrix structural constituent" 0006030=chitin metabolic process "0031012=extracellular matrix, 0005576=extracellular region" "CG31439, Muc96D" IPR002557=Chitin binding domain CG31439 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0265758 CR44565 http://flybase.net/reports/FBgn0265758.html non_protein_coding_gene lincRNA.590 CR44565 16-Dec-15 2015_12 FBgn0035954 Doc3 Dorsocross3 http://flybase.net/reports/FBgn0035954.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0035051=cardiocyte differentiation, 0061327=anterior Malpighian tubule development, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "dorsocross, Dm-DOC3, CG5093, Dorsocross, doc3, Doc" "IPR008967=p53-like transcription factor, DNA-binding, IPR018186=Transcription factor, T-box, conserved site, IPR001699=Transcription factor, T-box, IPR002070=Transcription factor, Brachyury" CG5093 16-Dec-15 2015_12 WBGene00006543(tbx-2) ENSXETG00000004260(TEgg048b09.1) ENSMUSG00000030699(Tbx6) embryonic stage--pupal stage " embryonic stage , embryonic stage | stage 15-16 , embryonic stage | stage 5-15 , embryonic stage | stage 9-16 , embryonic stage | stage 5-11 " " mesoderm | restricted

, embryonic anterior Malpighian tubule

, abdominal lateral pentascolopidial chordotonal organ lch5

, amnioserosa

, parasegment && ectoderm && mesoderm

, cardioblast | subset

, dorsal pouch

, organism | dorso-lateral

, procephalic neurogenic region

" "viable,chemical resistant" FBgn0063373 snoRNA:snR38:54Ec snoRNA:snR38:54Ec http://flybase.net/reports/FBgn0063373.html snoRNA_gene "Snr38snoRNA, CR32901" CR32901 16-Dec-15 2015_12 FBgn0060621 l(3)S088501b lethal (3) S088501b http://flybase.net/reports/FBgn0060621.html gene 0885/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0038181 CG9297 http://flybase.net/reports/FBgn0038181.html protein_coding_gene 0005509=calcium ion binding 0006816=calcium ion transport Dmel\CG9297 IPR027417=P-loop containing nucleoside triphosphate hydrolase CG9297 16-Dec-15 2015_12 ENSMUSG00000022519(Srl) ENSG00000185739(SRL) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC16469 E 1.132200079 0.799375909 4.004378938 -1.050881108 -0.225437855 0.043052098 FBgn0052671 Rab9Fa Rab at 9Fa http://flybase.net/reports/FBgn0052671.html FBgn0030253 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0015031=protein transport, 0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction" 0031982=vesicle "Rab GTPase 9Fa, RabX3, DmRabX3, CG2532, CG32671" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR003579=Small GTPase superfamily, Rab type, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG32671 16-Dec-15 2015_12 FBgn0024545 l(3)L3130 lethal (3) L3130 http://flybase.net/reports/FBgn0024545.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061129 l(3)S003003a lethal (3) S003003a http://flybase.net/reports/FBgn0061129.html gene "0030/03, l(3)S003003" 16-Dec-15 2015_12 "lethal,recessive" FBgn0005371 whg whiting http://flybase.net/reports/FBgn0005371.html gene 16-Dec-15 2015_12 eye color defective eye FBgn0060763 l(3)S063207 lethal (3) S063207 http://flybase.net/reports/FBgn0060763.html gene 0632/07 16-Dec-15 2015_12 FBgn0264862 CR44053 http://flybase.net/reports/FBgn0264862.html non_protein_coding_gene CR44053 16-Dec-15 2015_12 FBgn0259933 CG42456 http://flybase.net/reports/FBgn0259933.html protein_coding_gene 0009059=macromolecule biosynthetic process 0030176=integral component of endoplasmic reticulum membrane Dromel_CG12016_FBtr0073063_uORF IPR009914=Dolichol phosphate-mannose biosynthesis regulatory CG42456 16-Dec-15 2015_12 FBgn0039282 Bili Band4.1 inhibitor LRP interactor http://flybase.net/reports/FBgn0039282.html protein_coding_gene "0030178=negative regulation of Wnt signaling pathway, 0070201=regulation of establishment of protein localization" "0005856=cytoskeleton, 0005886=plasma membrane" "Band 4.1 FERM-like, CG11848, dBili" "IPR019749=Band 4.1 domain, IPR019748=FERM central domain, IPR000299=FERM domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle" CG11848 16-Dec-15 2015_12 ENSMUSG00000024816(Frmd8) "viable,fertile" embryonic/first instar larval cuticle DRSC14405 IE 2.30752901 1.149307697 4.38860131 -0.530758612 1.121567693 0.456002575 FBgn0264001 bru-3 bruno-3 http://flybase.net/reports/FBgn0264001.html "FBgn0262350, FBgn0036379, FBgn0036378, FBgn0010879, FBgn0085272" protein_coding_gene "0042803=protein homodimerization activity, 0003729=mRNA binding, 0000166=nucleotide binding, 0003723=RNA binding" 0017148=negative regulation of translation 0043234=protein complex "cg12478, bruno-3, lethal (3) 05871, l(3)05871, CG43744, cg10046, CG12478, CG10046, CG34243, Bru-3, bruno3, Dm Bru-3" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG43744 16-Dec-15 2015_12 "ENSDARG00000070045(zgc:92761),ENSDARG00000034668(celf3),ENSDARG00000006983,ENSDARG00000071375(celf5)" "ENSMUSG00000024268(Celf4),ENSMUSG00000028137(Celf3),ENSMUSG00000032297(Celf6),ENSMUSG00000034818(Celf5)" "ENSG00000159409(CELF3),ENSG00000101489(CELF4),ENSG00000140488(CELF6),ENSG00000161082(CELF5)" DRSC22732 K -0.392388607 0.492353085 0.415812704 0.672242204 1.642179667 1.863616238 FBgn0259390 C403 http://flybase.net/reports/FBgn0259390.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta,ectopic" FBgn0050340 CG30340 http://flybase.net/reports/FBgn0050340.html FBgn0045763 protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity" "0007165=signal transduction, 0007186=G-protein coupled receptor signaling pathway" 0016021=integral component of membrane "BACR48G21.1, BG:BACR48G21.1" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG30340 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0038386 CG5478 http://flybase.net/reports/FBgn0038386.html protein_coding_gene CG5478 16-Dec-15 2015_12 viable FBgn0069990 BG01954 BG01954 http://flybase.net/reports/FBgn0069990.html gene 16-Dec-15 2015_12 stress response defective FBgn0043979 Su(tor)293-12-3 Su(tor)293-12-3 http://flybase.net/reports/FBgn0043979.html gene 293-12-3 16-Dec-15 2015_12 FBgn0053201 CG33201 http://flybase.net/reports/FBgn0053201.html FBgn0064769 protein_coding_gene 16-Dec-15 2015_12 FBgn0060308 l(3)S148214 lethal (3) S148214 http://flybase.net/reports/FBgn0060308.html gene 1482/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0259258 EP-165 http://flybase.net/reports/FBgn0259258.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0020652 HIF Hypoxia Inducible Factor http://flybase.net/reports/FBgn0020652.html gene "0001666=response to hypoxia, 0007426=tracheal outgrowth, open tracheal system" "HIF-1, HIF-D, Hif-1" 16-Dec-15 2015_12 FBgn0051634 Oatp26F Organic anion transporting polypeptide 26F http://flybase.net/reports/FBgn0051634.html "FBgn0031839, FBgn0040952, FBgn0042123" protein_coding_gene 0008514=organic anion transmembrane transporter activity 0015711=organic anion transport 0016020=membrane "organic anion transporter protein 26f, CG18784, CG11332, CG31634, oatp 26F, CG13767, oatp26F" "IPR004156=Organic anion transporter polypeptide OATP, IPR002350=Kazal domain, IPR020846=Major facilitator superfamily domain" CG31634 16-Dec-15 2015_12 WBGene00018739(F53B1.8) ENSXETG00000023865() ENSMUSG00000038963(Slco4a1) ENSG00000101187(SLCO4A1) viable FBgn0027254 l(1)G0249 lethal (1) G0249 http://flybase.net/reports/FBgn0027254.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265512 mlt mulet http://flybase.net/reports/FBgn0265512.html "FBgn0013647, FBgn0011226, FBgn0033495" protein_coding_gene "0007286=spermatid development, 0031117=positive regulation of microtubule depolymerization, 0007291=sperm individualization" 0005930=axoneme "TBCEL, Tbcel, ms(2)3, CG12214, ms(2)4210, ms(2)ry-3, ms(2)ry3, tubulin-specific chaperone E-like protein, TBCE-like" "IPR029071=Ubiquitin-related domain, IPR000626=Ubiquitin domain" CG12214 16-Dec-15 2015_12 ENSDARG00000002682(zgc:73220) WBGene00016866(coel-1) ENSXETG00000024614(TBCEL) ENSMUSG00000037287(Tbcel) ENSG00000154114(TBCEL) DRSC27515 K 0.371158683 0.177647002 -0.25916353 -0.37351947 -0.13896648 1.745850798 FBgn0046329 l(2)38Ca lethal (2) 38Ca http://flybase.net/reports/FBgn0046329.html gene lethal in 38C 16-Dec-15 2015_12 FBgn0027581 CG6191 http://flybase.net/reports/FBgn0027581.html protein_coding_gene "0051726=regulation of cell cycle, 0006909=phagocytosis, 0044719=regulation of imaginal disc-derived wing size" "Dromel_CG6191_FBtr0087678_mORF, unnamed, cables, BcDNA:GH06193" "IPR012388=CDK5 and ABL1 enzyme substrate 1/2, IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal" CG6191 16-Dec-15 2015_12 "ENSDARG00000062044,ENSDARG00000017154(si:dkey-223d9.4)" WBGene00022128(Y71F9B.6) "ENSXETG00000017180(CABLES1),ENSXETG00000002013(Q5M7J7_XENTR)" "ENSMUSG00000040957(Cables1),ENSMUSG00000038990(Cables2)" "ENSG00000134508(CABLES1),ENSG00000149679(CABLES2)" "viable,fertile,size defective" "wing,posterior" FBgn0035425 CG17746 http://flybase.net/reports/FBgn0035425.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0043169=cation binding" 0006470=protein dephosphorylation 0005829=cytosol "Protein Phosphatase 2C, PP2C, Cg17746" "IPR000222=PPM-type phosphatase, divalent cation binding, IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C" CG17746 16-Dec-15 2015_12 "YBL056W(PTC3),YER089C(PTC2)" WBGene00011953(T23F11.1) "viable,fertile,lethal" DRSC08521 E 0.012788365 1.009485774 0.993251345 1.900285157 -0.374090839 -0.240521204 FBgn0060825 l(3)S051303 lethal (3) S051303 http://flybase.net/reports/FBgn0060825.html gene 0513/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065302 l(2)SH1985 lethal (2) SH1985 http://flybase.net/reports/FBgn0065302.html gene l(2)SH2 1985 16-Dec-15 2015_12 "lethal,recessive" FBgn0002083 l(2)49Fl lethal (2) 49Fl http://flybase.net/reports/FBgn0002083.html gene "vr-15, l(2)vr15" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,heat sensitive,non-suppressor of variegation,dominant" FBgn0016744 Su(Raf)3C Su(Raf)3C http://flybase.net/reports/FBgn0016744.html gene 16-Dec-15 2015_12 FBgn0026647 l(2)8bb lethal (2) 8bb http://flybase.net/reports/FBgn0026647.html gene 8bb 16-Dec-15 2015_12 "lethal,recessive" FBgn0265737 CR44544 http://flybase.net/reports/FBgn0265737.html non_protein_coding_gene "incRNA.494, lincRNA.494" CR44544 16-Dec-15 2015_12 FBgn0011770 Gip GIP-like http://flybase.net/reports/FBgn0011770.html protein_coding_gene 0008903=hydroxypyruvate isomerase activity 0046487=glyoxylate metabolic process 0005576=extracellular region "gene C, glyoxylate-induced protein, hydroxypyruvate isomerase, T15, CG2227" "IPR013022=Xylose isomerase-like, TIM barrel domain, IPR026040=Hydroxypyruvate isomerase-like" CG2227 16-Dec-15 2015_12 ENSDARG00000030166(zgc:63850) WBGene00015483(C05D11.5) ENSXETG00000002253(HYI) ENSMUSG00000006395(Hyi) ENSG00000178922(HYI) viable FBgn0011909 tRNA:L3:49Fa transfer RNA:leu:49Fa http://flybase.net/reports/FBgn0011909.html "FBgn0003789, FBgn0052840, FBgn0052841, FBgn0060163" tRNA_gene "0033404=UUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR32841, tRNA[LEU], AE002787.trna17-LeuCAA, CR32840, tRNA[Leu], tRNA:L:CAA:AE002787-a, leu-a, DtL[a], chr2R.trna76-LeuCAA, tRNA:leu3:49Fa" CR32841 16-Dec-15 2015_12 FBgn0040239 bc10 bc10 http://flybase.net/reports/FBgn0040239.html FBgn0035616 protein_coding_gene "dbc10, CG4867" "IPR018015=Bladder cancer-related BC10-like, IPR009598=Bladder cancer-related BC10" CG4867 16-Dec-15 2015_12 ENSDARG00000052073(blcap) WBGene00022273(Y73E7A.6) ENSXETG00000025511(Q5M8I8_XENTR) ENSMUSG00000067787(Blcap) ENSG00000166619(BLCAP) viable FBgn0002720 mesA messy A http://flybase.net/reports/FBgn0002720.html gene "mes-A, l(3)mes-1A, messy" 16-Dec-15 2015_12 "lethal,visible,partially lethal - majority die,sterile" "head bristle,adult thorax & macrochaeta,anterior scutellar bristle,wing,posterior crossvein" FBgn0017422 anon-70Cb anon-70Cb http://flybase.net/reports/FBgn0017422.html gene t3 16-Dec-15 2015_12 embryonic stage && larval stage && pupal stage FBgn0025775 l(2)37Ad lethal (2) 37Ad http://flybase.net/reports/FBgn0025775.html gene "l(2)02660, l(2)02660r" 16-Dec-15 2015_12 "lethal,recessive" FBgn0033868 S-Lap7 Sperm-Leucylaminopeptidase 7 http://flybase.net/reports/FBgn0033868.html protein_coding_gene "0008235=metalloexopeptidase activity, 0004177=aminopeptidase activity, 0030145=manganese ion binding" "0032504=multicellular organism reproduction, 0006508=proteolysis" "0005615=extracellular space, 0005737=cytoplasm" "CG13340, S-LAP 7, Sperm-LeucylAminoPeptidase 7" "IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal" CG13340 16-Dec-15 2015_12 FBgn0263268 del3 http://flybase.net/reports/FBgn0263268.html gene 0008406=gonad development delayed gonad formation 3 16-Dec-15 2015_12 gonad FBgn0267029 CR45473 http://flybase.net/reports/FBgn0267029.html non_protein_coding_gene CR45473 16-Dec-15 2015_12 FBgn0027508 Tnks tankyrase http://flybase.net/reports/FBgn0027508.html FBgn0039351 protein_coding_gene "0003950=NAD+ ADP-ribosyltransferase activity, 0097110=scaffold protein binding, 0005200=structural constituent of cytoskeleton" "0090364=regulation of proteasome assembly, 0035220=wing disc development, 0006471=protein ADP-ribosylation, 0022416=chaeta development, 0007016=cytoskeletal anchoring at plasma membrane" "Tankyrase, CG17487, tankyrase, CG4719, DTNKS, Dm.pARTb, unnamed, dTNKS, BcDNA:LD22548" "IPR012317=Poly(ADP-ribose) polymerase, catalytic domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain" CG4719 16-Dec-15 2015_12 ENSDARG00000062897(si:ch211-155m12.3) ENSXETG00000008155(TNKS) "ENSMUSG00000031529(Tnks),ENSMUSG00000024811(Tnks2)" "ENSG00000107854(TNKS2),ENSG00000173273(TNKS)" viable FBgn0260334 GSd414 http://flybase.net/reports/FBgn0260334.html gene 16-Dec-15 2015_12 lethal FBgn0010587 l(2)04884 lethal (2) 04884 http://flybase.net/reports/FBgn0010587.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0036186 CG6071 http://flybase.net/reports/FBgn0036186.html protein_coding_gene "0008270=zinc ion binding, 0004177=aminopeptidase activity, 0008237=metallopeptidase activity" "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space "IPR024571=ERAP1-like C-terminal domain, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG6071 16-Dec-15 2015_12 viable FBgn0000632 fap female abdomen pattern http://flybase.net/reports/FBgn0000632.html gene 16-Dec-15 2015_12 "visible,female,recessive,body color defective" "abdominal tergite 6,abdominal tergite 7" FBgn0016702 Ras85D::Src64B Ras85D::Src64B http://flybase.net/reports/FBgn0016702.html engineered_fusion_gene 16-Dec-15 2015_12 "photoreceptor cell R7,eye" FBgn0000302 cha chaff http://flybase.net/reports/FBgn0000302.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0085673 Su(Ste):CR41533 http://flybase.net/reports/FBgn0085673.html FBan0041533 non_protein_coding_gene "CR41533, CG41533" CR41533 16-Dec-15 2015_12 FBgn0019623 Crlbp Chemical-sense-related lipophilic-ligand-binding protein http://flybase.net/reports/FBgn0019623.html gene 16-Dec-15 2015_12 FBgn0069229 gl(2L)343-11 gl(2L)343-11 http://flybase.net/reports/FBgn0069229.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect" FBgn0004938 ABO-YL Abnormal Oocyte on YL http://flybase.net/reports/FBgn0004938.html region ABO 16-Dec-15 2015_12 FBgn0004023 wrl whirligig http://flybase.net/reports/FBgn0004023.html gene "0007288=sperm axoneme assembly, 0007017=microtubule-based process" "EcRms4, ms(3)nc4, nc4" 16-Dec-15 2015_12 "male sterile,dominant,recessive,viable" spermatid axoneme FBgn0030621 CG15030 http://flybase.net/reports/FBgn0030621.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC19611 I 1.682582919 -1.125804612 -0.837113938 0.438017978 0.149972023 0.519726808 FBgn0022812 E(faf)E306 Enhancer of faf E306 http://flybase.net/reports/FBgn0022812.html gene 16-Dec-15 2015_12 viable FBgn0030687 CG17209 http://flybase.net/reports/FBgn0030687.html protein_coding_gene "0008270=zinc ion binding, 0032549=ribonucleoside binding, 0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity" 0006383=transcription from RNA polymerase III promoter 0005666=DNA-directed RNA polymerase III complex "IPR007080=RNA polymerase Rpb1, domain 1, IPR006592=RNA polymerase, N-terminal, IPR000722=RNA polymerase, alpha subunit, IPR007081=RNA polymerase Rpb1, domain 5, IPR007083=RNA polymerase Rpb1, domain 4, IPR007066=RNA polymerase Rpb1, domain 3, IPR015700=DNA-directed RNA polymerase III subunit RPC1" CG17209 16-Dec-15 2015_12 ENSDARG00000071269 YOR116C(RPO31) WBGene00004411(rpc-1) ENSMUSG00000025280(Polr3a) ENSG00000148606(POLR3A) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC19766 K -0.301337531 0.160980242 -0.963043534 0.482878275 2.135652684 -0.893814352 FBgn0034076 Jhedup Juvenile hormone esterase duplication http://flybase.net/reports/FBgn0034076.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "CG8424, JHE, JHEdup, Juvenile hormone esterase" "IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site, IPR019819=Carboxylesterase type B, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG8424 16-Dec-15 2015_12 "WBGene00015077(B0238.13),WBGene00016863(C52A10.2),WBGene00015067(B0238.1)" viable FBgn0053143 CG33143 http://flybase.net/reports/FBgn0053143.html "FBgn0034746, FBgn0034747" protein_coding_gene "mdcds_16487, CG4232, CG13509, 33143" "IPR013783=Immunoglobulin-like fold, IPR003961=Fibronectin type III" CG33143 16-Dec-15 2015_12 FBgn0065091 snmRNA:463 small non-messenger RNA 463 http://flybase.net/reports/FBgn0065091.html non_protein_coding_gene Dm-463 16-Dec-15 2015_12 FBgn0085547 CG40971 http://flybase.net/reports/FBgn0085547.html FBan0040971 protein_coding_gene 16-Dec-15 2015_12 FBgn0029033 l(2)Q73 lethal (2) Q73 http://flybase.net/reports/FBgn0029033.html gene Q73 16-Dec-15 2015_12 "lethal,recessive" FBgn0003106 PL(3)sp-W1 Polygenic locus sternopleural W1 http://flybase.net/reports/FBgn0003106.html gene "a, PL(3)sp[W1]" 16-Dec-15 2015_12 FBgn0034684 CG13501 http://flybase.net/reports/FBgn0034684.html protein_coding_gene IPR016024=Armadillo-type fold CG13501 16-Dec-15 2015_12 viable FBgn0038683 CG11779 http://flybase.net/reports/FBgn0038683.html "FBgn0045799, FBgn0064949" protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0015031=protein transport, 0006626=protein targeting to mitochondrion, 0071456=cellular response to hypoxia" 0005744=mitochondrial inner membrane presequence translocase complex "BEST:GM03811, BcDNA:GM03811, CG117799, GH-18370" "IPR017303=Mitochondrial import inner membrane translocase subunit Tim44, IPR007379=Tim44-like domain" CG11779 16-Dec-15 2015_12 ENSDARG00000042712(timm44) YIL022W(TIM44) WBGene00020383(T09B4.9) ENSXETG00000001779(TIMM44) ENSMUSG00000002949(Timm44) ENSG00000104980(TIMM44) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "eye,trichogen cell,mesothoracic tergum" FBgn0028120 l(3)S060313 lethal (3) S060313 http://flybase.net/reports/FBgn0028120.html gene l(3)s001813 16-Dec-15 2015_12 "lethal,recessive" FBgn0025840 E(var)915 E(var)915 http://flybase.net/reports/FBgn0025840.html gene E-915 16-Dec-15 2015_12 FBgn0024332 Mcm3 Minichromosome maintenance 3 http://flybase.net/reports/FBgn0024332.html FBgn0020632 protein_coding_gene "0005524=ATP binding, 0003682=chromatin binding, 0043138=3'-5' DNA helicase activity, 0003677=DNA binding" "0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0022008=neurogenesis, 0006270=DNA replication initiation, 0007095=mitotic G2 DNA damage checkpoint" "0042555=MCM complex, 0005656=nuclear pre-replicative complex" "Minichromosome maintenance-PCR2, McM3, DmMCM3, PCR2, MCM3, Mcp-PCR2, dMcm3, CG4206, DmMcm3, dMCM3, DmeMCM3" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008046=DNA replication licensing factor Mcm3, IPR031327=Mini-chromosome maintenance protein, IPR027925=MCM N-terminal domain, IPR012340=Nucleic acid-binding, OB-fold, IPR001208=MCM domain, IPR003593=AAA+ ATPase domain, IPR018525=Mini-chromosome maintenance, conserved site" CG4206 16-Dec-15 2015_12 "ENSDARG00000024204(mcm3),ENSDARG00000037532(mcm3l),ENSDARG00000068908" YEL032W(MCM3) WBGene00003155(mcm-3) "ENSXETG00000021701(mcm3),ENSXETG00000020538()" ENSMUSG00000041859(Mcm3) ENSG00000112118(MCM3) " adult stage | female , egg stage | unfertilized egg , embryonic stage | 0-4 hr , embryonic stage | stage 11-12 " " unfertilized egg

, embryonic central nervous system

" "radiation sensitive,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026077 Gasp Gasp http://flybase.net/reports/FBgn0026077.html FBgn0026290 protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region "anon-EST:ParkEST180, obst-C, CG10287, gammaBert27, gasp" IPR002557=Chitin binding domain CG10287 16-Dec-15 2015_12 viable FBgn0001983 wor worniu http://flybase.net/reports/FBgn0001983.html protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" "0007420=brain development, 0046331=lateral inhibition, 0006355=regulation of transcription, DNA-templated, 0007417=central nervous system development, 0055059=asymmetric neuroblast division, 0048813=dendrite morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "br35, l(2)br35, Worniu, D.m.Worniu, lethal(2)35Da, Wor, l(2)35Da, l35Da, warniu, CG4158, BG:DS03023.1, schnecke" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR029795=SNAIL family, IPR007087=Zinc finger, C2H2" CG4158 16-Dec-15 2015_12 ENSDARG00000031243(snai3) "ENSMUSG00000060257,ENSMUSG00000048385(Scrt1)" " embryonic stage | stage >=8 , embryonic stage | stage >=13 , embryonic stage | stage >=9 " " procephalic neurogenic region

, embryonic brain

, ventral nerve cord

, neuroblast

" "neuroanatomy defective,partially lethal - majority die,lethal,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,visible" "ventral nerve cord,denticle belt,embryonic/larval brain,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,chaeta,supernumerary" FBgn0010137 l(2)62B10 lethal (2) of Spiess 62B10 http://flybase.net/reports/FBgn0010137.html gene 16-Dec-15 2015_12 lethal FBgn0036575 CG5157 http://flybase.net/reports/FBgn0036575.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity" "IPR018506=Cytochrome b5, heme-binding site, IPR001199=Cytochrome b5-like heme/steroid binding domain" CG5157 16-Dec-15 2015_12 viable FBgn0058154 CG40154 http://flybase.net/reports/FBgn0058154.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034502 CG13871 http://flybase.net/reports/FBgn0034502.html protein_coding_gene CG13871 16-Dec-15 2015_12 viable FBgn0038647 CG14302 http://flybase.net/reports/FBgn0038647.html FBgn0063129 protein_coding_gene BcDNA:LP02994 CG14302 16-Dec-15 2015_12 viable FBgn0263378 CR43430 http://flybase.net/reports/FBgn0263378.html non_protein_coding_gene CR43430 16-Dec-15 2015_12 FBgn0022158 l(2)k05722 lethal (2) k05722 http://flybase.net/reports/FBgn0022158.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267443 CR45793 http://flybase.net/reports/FBgn0267443.html non_protein_coding_gene Mgn095159 CR45793 16-Dec-15 2015_12 FBgn0067870 Mod(Prat:bw)3-5 Mod(Prat:bw)3-5 http://flybase.net/reports/FBgn0067870.html gene Mod-3-5 16-Dec-15 2015_12 enhancer of variegation FBgn0032387 CG16965 http://flybase.net/reports/FBgn0032387.html protein_coding_gene "0004555=alpha,alpha-trehalase activity" 0005975=carbohydrate metabolic process "IPR012341=Six-hairpin glycosidase, IPR008928=Six-hairpin glycosidase-like, IPR005195=Glycoside hydrolase, family 65, central catalytic" CG16965 16-Dec-15 2015_12 ENSDARG00000014311(athl1) ENSXETG00000020609(ATHL1) ENSMUSG00000062031(Athl1) ENSG00000142102(ATHL1) viable FBgn0043557 Su(roDOM)2014 Su(roDOM)2014 http://flybase.net/reports/FBgn0043557.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0062643 EP707 EP707 http://flybase.net/reports/FBgn0062643.html gene EP(3)0707 16-Dec-15 2015_12 FBgn0082330 HM813 HM813 http://flybase.net/reports/FBgn0082330.html gene 16-Dec-15 2015_12 FBgn0002388 l(3)93Dd lethal (3) 93Dd http://flybase.net/reports/FBgn0002388.html gene "l(3)er9, er9" 16-Dec-15 2015_12 "visible,recessive,lethal" eye FBgn0002429 l(3)F55 lethal (3) F55 http://flybase.net/reports/FBgn0002429.html gene l(3)55 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0263382 CR43434 http://flybase.net/reports/FBgn0263382.html non_protein_coding_gene CR43434 16-Dec-15 2015_12 FBgn0261523 CG42658 http://flybase.net/reports/FBgn0261523.html protein_coding_gene 0005789=endoplasmic reticulum membrane "IPR008962=PapD-like, IPR016763=Vesicle-associated membrane-protein-associated protein, IPR000535=Major sperm protein (MSP) domain" CG42658 16-Dec-15 2015_12 FBgn0069304 X-86-9 X-86-9 http://flybase.net/reports/FBgn0069304.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect,filzkorper" FBgn0022970 snRNPA snRNPA http://flybase.net/reports/FBgn0022970.html gene "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" A 16-Dec-15 2015_12 FBgn0015488 l(2)46Cl lethal (2) 46Cl http://flybase.net/reports/FBgn0015488.html gene "T, Complementation group T" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0086913 Rab26 Rab26 http://flybase.net/reports/FBgn0086913.html "FBgn0037072, FBgn0052439, FBgn0085439, FBan0032439" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0017157=regulation of exocytosis, 0015031=protein transport, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport" "0031982=vesicle, 0031226=intrinsic component of plasma membrane, 0045202=synapse, 0055037=recycling endosome" "CG7605, CG34410, CG32439, DmRab26, rab26, AAF51708, Q9VP48, Q8IPT6" "IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG34410 16-Dec-15 2015_12 "WBGene00007067(4R79.2),WBGene00016344(tag-312)" "ENSMUSG00000020732(Rab37),ENSMUSG00000079657(Rab26)" "ENSG00000167964(RAB26),ENSG00000172794(RAB37)" viable FBgn0082355 HM298 HM298 http://flybase.net/reports/FBgn0082355.html gene 16-Dec-15 2015_12 FBgn0020881 als alae sublatae http://flybase.net/reports/FBgn0020881.html gene Mps1 16-Dec-15 2015_12 FBgn0016809 l(1)L10 lethal (1) L10 http://flybase.net/reports/FBgn0016809.html gene L10 16-Dec-15 2015_12 "lethal,recessive" FBgn0051238 CG31238 http://flybase.net/reports/FBgn0051238.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000564 Eh Eclosion hormone http://flybase.net/reports/FBgn0000564.html FBgn0026855 protein_coding_gene "0008255=ecdysis-triggering hormone activity, 0005184=neuropeptide hormone activity, 0008031=eclosion hormone activity" "0030534=adult behavior, 0007562=eclosion, 0007563=regulation of eclosion, 0018990=ecdysis, chitin-based cuticle, 0007218=neuropeptide signaling pathway" 0005615=extracellular space "DMEHAB, eh, EH, CG5400, EHAB, Drm-EH, eclosion hormone" IPR006825=Eclosion hormone CG5400 16-Dec-15 2015_12 FBgn0030191 CG15306 http://flybase.net/reports/FBgn0030191.html protein_coding_gene 0008017=microtubule binding 0046427=positive regulation of JAK-STAT cascade "IPR027328=Microtubule-associated protein RP/EB, IPR001715=Calponin homology domain" CG15306 16-Dec-15 2015_12 viable FBgn0035170 dpr20 defective proboscis extension response 20 http://flybase.net/reports/FBgn0035170.html protein_coding_gene 0007606=sensory perception of chemical stimulus "CT9818, Dpr20, CG12191, Dpr-20, defective proboscis extension response 20, dpr20" "IPR013151=Immunoglobulin, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG12191 16-Dec-15 2015_12 viable FBgn0004186 snRNA:U1:95Cb small nuclear RNA U1 at 95Cb http://flybase.net/reports/FBgn0004186.html "FBgn0003915, FBgn0003918" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005685=U1 snRNP "U1snRNA, U1-95.2, snRNA:U1:95CB, U1:95Cb, U1snRNA95Cb, U1, 95C U1, U1a-95Cb, U1-95Cb, small nuclear RNA U1, U1 snRNA, K5, U1:95C, snRNA-U1-95.2, snRNA:U1, CR32866" CR32866 16-Dec-15 2015_12 FBgn0063485 Lasp Lasp http://flybase.net/reports/FBgn0063485.html "FBgn0016776, FBgn0036653" protein_coding_gene "0005515=protein binding, 0003779=actin binding, 0008270=zinc ion binding" "0007279=pole cell formation, 0045214=sarcomere organization, 0007283=spermatogenesis, 0071689=muscle thin filament assembly, 0014881=regulation of myofibril size, 0007291=sperm individualization, 0045856=positive regulation of pole plasm oskar mRNA localization" "0031672=A band, 0005829=cytosol, 0015629=actin cytoskeleton, 0030018=Z disc, 0070864=sperm individualization complex, 0005925=focal adhesion" "lasp, cDNA B, unnamed, anon-73Bd, CG3849" "IPR001781=Zinc finger, LIM-type, IPR001452=SH3 domain, IPR000900=Nebulin repeat" CG3849 16-Dec-15 2015_12 WBGene00018367(F42H10.3) "ENSXETG00000016599(),ENSXETG00000023716(lasp1)" ENSMUSG00000053702(Nebl) "partially lethal - majority die,hatching behavior defective,decreased cell number,grandchildless,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,visible,viable,male sterile,female fertile,reduced" "pole cell,ectopic,hub cell,trichogen cell,mesothoracic tergum,investment cone,individualization stage spermatid" DRSC10379 EK -0.43576585 0.184164187 -0.940571665 1.503371166 2.30026385 0.235878809 FBgn0265010 Ms(3)88C Male sterile (3) 88C http://flybase.net/reports/FBgn0265010.html gene 16-Dec-15 2015_12 FBgn0084325 su(eas)13 su(eas)13 http://flybase.net/reports/FBgn0084325.html gene 16-Dec-15 2015_12 viable FBgn0001529 l(1)11Ee lethal (1) 11Ee http://flybase.net/reports/FBgn0001529.html gene 16-Dec-15 2015_12 lethal FBgn0016669 Hrp75 Hrp75 http://flybase.net/reports/FBgn0016669.html gene 0003697=single-stranded DNA binding hrp75 16-Dec-15 2015_12 FBgn0031968 CG7231 http://flybase.net/reports/FBgn0031968.html protein_coding_gene IPR019356=Protein of unknown function DUF2181 CG7231 16-Dec-15 2015_12 ENSDARG00000020024(zgc:100861) ENSXETG00000018162(FAM151B) ENSMUSG00000034334(Fam151b) ENSG00000152380(FAM151B) "lethal,recessive,viable,fertile" FBgn0039616 CG11828 http://flybase.net/reports/FBgn0039616.html protein_coding_gene "0005506=iron ion binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity" "0055114=oxidation-reduction process, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0032504=multicellular organism reproduction" "0005783=endoplasmic reticulum, 0016222=procollagen-proline 4-dioxygenase complex" "IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG11828 16-Dec-15 2015_12 viable FBgn0041184 Socs36E Suppressor of cytokine signaling at 36E http://flybase.net/reports/FBgn0041184.html "FBgn0025963, FBgn0032667" protein_coding_gene "0046425=regulation of JAK-STAT cascade, 0007259=JAK-STAT cascade, 0045677=negative regulation of R7 cell differentiation, 0030718=germ-line stem cell maintenance, 0043697=cell dedifferentiation, 0048802=notum morphogenesis, 0007298=border follicle cell migration, 0008586=imaginal disc-derived wing vein morphogenesis, 0048072=compound eye pigmentation, 0046426=negative regulation of JAK-STAT cascade, 0045873=negative regulation of sevenless signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0007616=long-term memory, 0007482=haltere development" "clone 2.2, SocS36E, suppressor of cytokine signaling 36E, anon-EST:Liang-2.2, Socs, CG15154, socs36e, Suppressor of cytokine signaling 36E, socs60E1, socs36E, SOCS, SOCS36E, dSOCS, suppressor of cytokine signaling, Suppressor of cytokine signaling, dmSocs36E, Suppressor of Cytokine Signaling 36E" "IPR000980=SH2 domain, IPR028413=Suppressor of cytokine signalling, IPR001496=SOCS box domain" CG15154 16-Dec-15 2015_12 "ENSDARG00000058565(LOC558703),ENSDARG00000015863(socs6b)" "visible,viable,fertile,male semi-sterile,lethal - all die before end of P-stage,partially,some die during pharate adult stage,short lived,memory defective,RU486 conditional" "anterior crossvein,wing vein,ectopic,eye,photoreceptor cell R7,supernumerary,cyst progenitor cell,male,male germline stem cell,somatic clone,border follicle cell,humerus,haltere,pigment cell,wing,germline cell" DRSC02455 IEK 0.507591113 -2.900628656 -1.232231707 2.41611484 -0.768366818 2.089294204 FBgn0034787 CG13535 http://flybase.net/reports/FBgn0034787.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036433 CG9628 http://flybase.net/reports/FBgn0036433.html protein_coding_gene CG9628 16-Dec-15 2015_12 "viable,fertile" FBgn0264656 paltry paltry http://flybase.net/reports/FBgn0264656.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0029715 CG11444 http://flybase.net/reports/FBgn0029715.html protein_coding_gene 0044822=poly(A) RNA binding "IPR019380=Casein kinase substrate, phosphoprotein PP28" CG11444 16-Dec-15 2015_12 "ENSDARG00000002967(pdap1),ENSDARG00000045153(slc16a8)" ENSXETG00000006062(PDAP1) ENSMUSG00000029623(Pdap1) ENSG00000106244(PDAP1) viable FBgn0041707 7B2 7B2 http://flybase.net/reports/FBgn0041707.html FBgn0037318 protein_coding_gene 0016504=peptidase activator activity "0007218=neuropeptide signaling pathway, 0010952=positive regulation of peptidase activity, 0016486=peptide hormone processing, 0045862=positive regulation of proteolysis" 0030141=secretory granule "FBgn0040073, d7B2, CG1168, unnamed" IPR007945=Neuroendocrine 7B2 precursor CG1168 16-Dec-15 2015_12 ENSDARG00000032126(LOC100330746) WBGene00011392(sbt-1) ENSMUSG00000023236(Scg5) ENSG00000166922(SCG5) viable FBgn0044496 DTD45.10 DTD45.10 http://flybase.net/reports/FBgn0044496.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020418 I-element\RTase I element reverse transcriptase http://flybase.net/reports/FBgn0020418.html FBgn0013982 transposable_element_gene "0004523=RNA-DNA hybrid ribonuclease activity, 0003676=nucleic acid binding" "I\T, I-Factor ORF2, ORF2p, I-element transposase, I-element ORF2, ORF2" "IPR012337=Ribonuclease H-like domain, IPR005135=Endonuclease/exonuclease/phosphatase, IPR000477=Reverse transcriptase domain, IPR002156=Ribonuclease H domain" 16-Dec-15 2015_12 FBgn0259110 mmd mind-meld http://flybase.net/reports/FBgn0259110.html "FBgn0030712, FBgn0030713, FBgn0041109, FBgn0030714" protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" 0006509=membrane protein ectodomain proteolysis 0016021=integral component of membrane "Meltrin-like, CT26192, CG42252, CG15603, CG9163, CG15604, Mind meld" "IPR001762=Disintegrin domain, IPR013032=EGF-like, conserved site, IPR013111=EGF-like domain, extracellular, IPR018358=Disintegrin, conserved site, IPR002870=Peptidase M12B, propeptide, IPR006586=ADAM, cysteine-rich, IPR024079=Metallopeptidase, catalytic domain, IPR000742=EGF-like domain, IPR001590=Peptidase M12B, ADAM/reprolysin" CG42252 16-Dec-15 2015_12 WBGene00006804(unc-71) "ENSG00000197140(ADAM32),ENSG00000168619(ADAM18),ENSG00000104755(ADAM2),ENSG00000168615(ADAM9),ENSG00000168594(ADAM29),ENSG00000139985,ENSG00000134007(ADAM20),ENSG00000134249(ADAM30)" DRSC20161 K 0.349532796 0.981301964 0.50742409 0.704442635 -1.675367721 -0.850084718 FBgn0265064 CR44175 http://flybase.net/reports/FBgn0265064.html non_protein_coding_gene lincRNA.812 CR44175 16-Dec-15 2015_12 FBgn0052123 tRNA:CR32123:ë¬ transfer RNA:CR32123:pseudogene http://flybase.net/reports/FBgn0052123.html FBgn0060170 pseudogene_attribute "AE002602.trna21-LeuAAG, CR32123, tRNA:L:AAG:AE002602" CR32123 16-Dec-15 2015_12 FBgn0028635 ifm(2)RU7 indirect flight muscle (2) RU7 http://flybase.net/reports/FBgn0028635.html gene 0007517=muscle organ development 0005703=polytene chromosome puff 16-Dec-15 2015_12 "visible,recessive,flight defective,sterile,viable" "wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0001385 l(1)2Bq lethal (1) 2Bq http://flybase.net/reports/FBgn0001385.html gene 16-Dec-15 2015_12 lethal FBgn0036785 CG13700 http://flybase.net/reports/FBgn0036785.html protein_coding_gene CG13700 16-Dec-15 2015_12 viable FBgn0065134 l(3)SH123 lethal (3) SH123 http://flybase.net/reports/FBgn0065134.html gene l(2)SH3 123 16-Dec-15 2015_12 "lethal,recessive" FBgn0267305 CR45741 http://flybase.net/reports/FBgn0267305.html non_protein_coding_gene CR45741 16-Dec-15 2015_12 FBgn0261001 AGAR-53 Autosomal general anesthetic resistant 53 http://flybase.net/reports/FBgn0261001.html gene autosomal general anesthetic resistant 53 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0038677 CG14284 http://flybase.net/reports/FBgn0038677.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065678 l(2)SH0671 lethal (2) SH0671 http://flybase.net/reports/FBgn0065678.html gene l(2)SH2 0671 16-Dec-15 2015_12 "lethal,recessive" FBgn0028069 l(3)S090314 lethal (3) S090314 http://flybase.net/reports/FBgn0028069.html gene 0903/14 16-Dec-15 2015_12 "viable,lethal,recessive" FBgn0084568 E-2fa Enhancer on chromosome 2-complementation group fa http://flybase.net/reports/FBgn0084568.html gene E-2f 16-Dec-15 2015_12 FBgn0020805 ms(3)1100A male sterile (3) 1100A http://flybase.net/reports/FBgn0020805.html gene 16-Dec-15 2015_12 male sterile FBgn0083283 E(smoDN)2169 Enhancer of smoDN 2169 http://flybase.net/reports/FBgn0083283.html gene 16-Dec-15 2015_12 FBgn0022972 snRNP42K snRNP42K http://flybase.net/reports/FBgn0022972.html gene "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" 42K 16-Dec-15 2015_12 FBgn0027320 l(1)G0062 lethal (1) G0062 http://flybase.net/reports/FBgn0027320.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069165 mcl(3)Z1492 mcl(3)Z1492 http://flybase.net/reports/FBgn0069165.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0011916 tRNA:M2:48Bb transfer RNA:met2:48Bb http://flybase.net/reports/FBgn0011916.html "FBgn0003807, FBgn0052844, FBgn0060139" tRNA_gene "0033436=AUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:M:CAT:AE002787-b, AE002787.trna22-MetCAT, tRNA:met2:48Bb, CR32844, chr2R.trna81-MetCAT" CR32844 16-Dec-15 2015_12 FBgn0065628 l(2)SH0791 lethal (2) SH0791 http://flybase.net/reports/FBgn0065628.html gene l(2)SH2 0791 16-Dec-15 2015_12 "lethal,recessive" FBgn0016834 l(1)MZ21 lethal (1) MZ21 http://flybase.net/reports/FBgn0016834.html gene M21 16-Dec-15 2015_12 "lethal,recessive" FBgn0051876 Cpr30F Cuticular protein 30F http://flybase.net/reports/FBgn0051876.html FBgn0032165 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0008011=structural constituent of pupal chitin-based cuticle, 0005214=structural constituent of chitin-based cuticle" "0040003=chitin-based cuticle development, 0022008=neurogenesis" 0031012=extracellular matrix "DmelCpr30F, CG31876, CG5879" IPR000618=Insect cuticle protein CG31876 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001774 l(1)M52 lethal (1) M52 http://flybase.net/reports/FBgn0001774.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051864 Qtzl Quetzalcoatl http://flybase.net/reports/FBgn0051864.html FBgn0032392 protein_coding_gene 0008152=metabolic process "CG31864-PA, CG31864, CG17749" "IPR000192=Aminotransferase class V domain, IPR015424=Pyridoxal phosphate-dependent transferase" CG31864 16-Dec-15 2015_12 "viable,sterile,recessive" FBgn0034792 CG3499 http://flybase.net/reports/FBgn0034792.html protein_coding_gene "0005524=ATP binding, 0004222=metalloendopeptidase activity, 0004176=ATP-dependent peptidase activity" 0006508=proteolysis 0005743=mitochondrial inner membrane DmCG3499 "IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR005936=Peptidase, FtsH, IPR000642=Peptidase M41, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG3499 16-Dec-15 2015_12 ENSDARG00000063349 YPR024W(YME1) WBGene00010842(ymel-1) ENSXETG00000004558(YME1L1) ENSMUSG00000026775(Yme1l1) ENSG00000136758(YME1L1) "viable,visible" trichogen cell FBgn0033590 CG13217 http://flybase.net/reports/FBgn0033590.html FBgn0063035 protein_coding_gene BcDNA:RE32413 CG13217 16-Dec-15 2015_12 viable FBgn0045858 e(Pi3K92E)alpha e(Pi3K92E)alpha http://flybase.net/reports/FBgn0045858.html gene alpha 16-Dec-15 2015_12 FBgn0041597 l(2)PJ20 lethal (2) PJ20 http://flybase.net/reports/FBgn0041597.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060311 l(3)S147912 lethal (3) S147912 http://flybase.net/reports/FBgn0060311.html gene 1479/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003568 su(lz34) suppressor of lozenge-34 http://flybase.net/reports/FBgn0003568.html gene su(lz[34k]) 16-Dec-15 2015_12 "female fertile,good" "female accessory gland,spermathecum,eye" FBgn0264397 FCP-E http://flybase.net/reports/FBgn0264397.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0052328 tRNA:CR32328 transfer RNA:CR32328 http://flybase.net/reports/FBgn0052328.html FBgn0060252 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:E:CTC:AE002584-b, AE002584.trna4-GluCTC, chr3L.trna4-GluCTC, CR32328" CR32328 16-Dec-15 2015_12 FBgn0030262 Vago Vago http://flybase.net/reports/FBgn0030262.html "FBgn0062908, FBtr0073427, FBpp0073283" protein_coding_gene 0051607=defense response to virus 0005615=extracellular space "BcDNA:RH70969, CG2081, DIGF-2" IPR029277=Single domain Von Willebrand factor type C domain CG2081 16-Dec-15 2015_12 "viable,fertile" FBgn0051432 tRNA:CR31432 transfer RNA:CR31432 http://flybase.net/reports/FBgn0051432.html "FBgn0011989, FBgn0060037" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033439=ACA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR31432, tRNA:T3:87BC, tRNA:thr3:87BC, tRNA:T:TGT:AE002708-b, chr3R.trna61-ThrTGT, transfer RNA:thr3:87BC, AE002708.trna55-ThrTGT, tRNA[Thr][[3]], tRNA[[Thr]]" CR31432 16-Dec-15 2015_12 FBgn0031455 Snapin Snapin ortholog (H. sapiens) http://flybase.net/reports/FBgn0031455.html FBgn0052951 protein_coding_gene 0005515=protein binding "0016082=synaptic vesicle priming, 0006886=intracellular protein transport, 0007269=neurotransmitter secretion, 0016079=synaptic vesicle exocytosis, 0032844=regulation of homeostatic process" "0008021=synaptic vesicle, 0031083=BLOC-1 complex" "CG32951, Snapin, SNAPIN, snapin, Dromel_CG9960_CG9958_FBtr007773_snapin_uORF, NP_722835, CG9958" "IPR028119=Snapin/Pallidin/Snn1, IPR017246=Snapin" CG9958 16-Dec-15 2015_12 ENSDARG00000062382(si:dkey-222b8.2) ENSMUSG00000001018(Snapin) ENSG00000143553(SNAPIN) "lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective,drug conditional,female fertile" DRSC00736 E -0.117033922 0.993273659 1.590928682 0.825585157 0.007598632 -0.001642737 FBgn0052455 CG32455 http://flybase.net/reports/FBgn0052455.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002752 mit(1)2 mitotic 2 http://flybase.net/reports/FBgn0002752.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0083048 snoRNA:ë¬18S-1377d snoRNA:ë¬18S-1377d http://flybase.net/reports/FBgn0083048.html snoRNA_gene "psi18S-1377d, Psi18S-1377d, CR34626, chr3R:26032931..26033021" CR34626 16-Dec-15 2015_12 FBgn0036192 Pallidin Pallidin ortholog (H. sapiens) http://flybase.net/reports/FBgn0036192.html protein_coding_gene 0005515=protein binding 0008057=eye pigment granule organization 0031083=BLOC-1 complex "pallidin, CG14133, Pallidin, NP_648494" "IPR017242=BLOC-1 complex, pallidin subunit, IPR028119=Snapin/Pallidin/Snn1" CG14133 16-Dec-15 2015_12 ENSDARG00000042933(zgc:158718) ENSXETG00000022045(pldn) ENSMUSG00000005804(Pldn) ENSG00000104164(PLDN) "eye color defective,viable" FBgn0067329 3F43 3F43 http://flybase.net/reports/FBgn0067329.html gene 0008587=imaginal disc-derived wing margin morphogenesis 16-Dec-15 2015_12 "visible,somatic clone" "wing sensillum,ectopic,somatic clone" FBgn0085540 CR40947 http://flybase.net/reports/FBgn0085540.html FBan0040947 non_protein_coding_gene CG40947 CR40947 16-Dec-15 2015_12 FBgn0263231 bel belle http://flybase.net/reports/FBgn0263231.html "FBgn0000171, FBgn0002312, FBgn0011214, FBgn0037604, FBgn0041772, FBgn0028143, FBgn0024557" protein_coding_gene "0008026=ATP-dependent helicase activity, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0003676=nucleic acid binding" "0002168=instar larval development, 0007286=spermatid development, 0016246=RNA interference, 0000070=mitotic sister chromatid segregation, 0010468=regulation of gene expression, 0048477=oogenesis, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007283=spermatogenesis" "0005829=cytosol, 0005737=cytoplasm, 0005811=lipid particle, 0005875=microtubule associated complex, 0016442=RISC complex, 0043186=P granule, 0043025=neuronal cell body" "anon-85Ab, cg9748, l(3)85Ac, ms(3)Pneo85A, BEL, l(3)L4740, CG9748, lethal (3) S047110, l(3)S097074, ms(3)neo30, Belle, L3, cap, unnamed, capon, Bel, psg9, DmRH6, l(3)L3, belle, lethal (3) L4740, l(3)S047110" "IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain" CG9748 16-Dec-15 2015_12 "ENSDARG00000020573(ddx3),ENSDARG00000005774(pl10)" "YPL119C(DBP1),YOR204W(DED1)" WBGene00022184 ENSXETG00000015477(ddx3x) "ENSMUSG00000000787(Ddx3x),ENSMUSG00000039224(D1Pas1),ENSMUSG00000069045(Ddx3y)" "ENSG00000215301(DDX3X),ENSG00000067048(DDX3Y)" DRSC25066 IK -2.737597649 -0.844103717 -0.809998272 0.190823138 0.35739607 3.248510243 FBgn0051913 CG31913 http://flybase.net/reports/FBgn0051913.html "FBgn0045092, FBgn0045156, FBgn0045200, FBgn0045297, FBgn0045349" protein_coding_gene "NEST:bs14h07, NEST:bs28e01, NEST:bs35c08, NEST:bs23g06, NEST:bs09g05" IPR014807=Cytochrome oxidase assembly protein 1 CG31913 16-Dec-15 2015_12 ENSG00000106603(C7orf44) viable FBgn0026224 l(1)16Fq lethal (1) 16Fq http://flybase.net/reports/FBgn0026224.html gene ME-V 16-Dec-15 2015_12 lethal FBgn0065653 l(2)SH0728 lethal (2) SH0728 http://flybase.net/reports/FBgn0065653.html gene l(2)SH2 0728 16-Dec-15 2015_12 "lethal,recessive" FBgn0259711 CG42365 http://flybase.net/reports/FBgn0259711.html "FBgn0034648, FBan0015675" protein_coding_gene CG15675 CG42365 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0011060 l(1)Q13 lethal (1) Q13 http://flybase.net/reports/FBgn0011060.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0040553 CG14374 http://flybase.net/reports/FBgn0040553.html protein_coding_gene CG14374 16-Dec-15 2015_12 FBgn0010401 Os-C Os-C http://flybase.net/reports/FBgn0010401.html protein_coding_gene 0005550=pheromone binding "Os-c, CG3250, OS-C" CG3250 16-Dec-15 2015_12 adult stage " sacculus

, antennal segment 3

" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0058040 CG40040 http://flybase.net/reports/FBgn0058040.html FBan0040040 protein_coding_gene 16-Dec-15 2015_12 FBgn0033729 Cpr49Af Cuticular protein 49Af http://flybase.net/reports/FBgn0033729.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG8510, DmelCpr49Af" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8510 16-Dec-15 2015_12 FBgn0037964 CG14731 http://flybase.net/reports/FBgn0037964.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi7299531, gi21483202" "IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG14731 16-Dec-15 2015_12 "viable,fertile" FBgn0002750 misp misstep http://flybase.net/reports/FBgn0002750.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic segment" FBgn0046118 E(To)8 E(To)8 http://flybase.net/reports/FBgn0046118.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028214 l(3)S009720 lethal (3) S009720 http://flybase.net/reports/FBgn0028214.html gene 0097/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0033865 CG6220 http://flybase.net/reports/FBgn0033865.html protein_coding_gene "0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter" 0016593=Cdc73/Paf1 complex "IPR007852=Cdc73/Parafibromin, IPR031336=Cell division control protein 73, C-terminal" CG6220 16-Dec-15 2015_12 viable FBgn0011231 sdl seedless http://flybase.net/reports/FBgn0011231.html gene 0007286=spermatid development 16-Dec-15 2015_12 "male sterile,recessive" FBgn0032925 CG9246 http://flybase.net/reports/FBgn0032925.html protein_coding_gene 0022008=neurogenesis 0005730=nucleolus "IPR005343=Nucleolar complex protein 2, IPR016024=Armadillo-type fold" CG9246 16-Dec-15 2015_12 ENSDARG00000001754(noc2l) YOR206W(NOC2) ENSG00000188976(NOC2L) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0002789 Mp20 Muscle protein 20 http://flybase.net/reports/FBgn0002789.html "FBgn0003740, FBgn0026854" protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding" "0008360=regulation of cell shape, 0007520=myoblast fusion, 1901739=regulation of myoblast fusion, 0007155=cell adhesion" 0043292=contractile fiber "Muscle Protein 20, MP20, mp20, myophilin, Tpn, DMMP20, Dmmp20, muscle protein 20, Muscle protein 20 kd, CG4696" "IPR000557=Calponin repeat, IPR001715=Calponin homology domain, IPR003096=Smooth muscle protein/calponin" CG4696 16-Dec-15 2015_12 "ENSDARG00000033466(tagln2),ENSDARG00000045408(tagln),ENSDARG00000058394(zgc:66052),ENSDARG00000013831(tagln3)" YOR367W(SCP1) " embryonic stage | 12-24 hr , adult stage , prepupal stage , pupal stage | early " adult stage synchronous muscle

"viable,visible" "dorsal acute muscle 1,nucleus | supernumeraryeve.eme,trichogen cell,supernumerary,tormogen cell,embryonic myoblast,dorsal transverse muscle,ventral acute muscle 2,segment border muscle,nucleushow-24B" FBgn0051675 CG31675 http://flybase.net/reports/FBgn0051675.html FBgn0063687 protein_coding_gene BcDNA:RE19849 CG31675 16-Dec-15 2015_12 viable FBgn0026380 Prosë_3 Proteasome ë_3 subunit http://flybase.net/reports/FBgn0026380.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0022008=neurogenesis, 0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005839=proteasome core complex, 0000502=proteasome complex" "beta-3, 20S proteasome, 20s proteasome, Beta-3, Pros beta3, beta3, Prosbeta3, 20S proteasome beta3 subunit, CG11981, 11981" "IPR016050=Proteasome beta-type subunit, conserved site, IPR001353=Proteasome, subunit alpha/beta, IPR023333=Proteasome B-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal" CG11981 16-Dec-15 2015_12 ENSDARG00000013938(psmb3) YER094C(PUP3) WBGene00003949(pbs-3) ENSXETG00000014713(psmb3) "ENSMUSG00000069744(Psmb3),ENSMUSG00000069379,ENSMUSG00000069962" ENSG00000108294(PSMB3) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16801 IE -3.090109855 -5.477058347 -3.845298976 -2.891937368 1.281761475 -0.036620931 FBgn0002206 l(3)67BDd lethal (3) 67BDd http://flybase.net/reports/FBgn0002206.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0014364 myoblast-specific myoblast specific http://flybase.net/reports/FBgn0014364.html gene mas 16-Dec-15 2015_12 FBgn0040487 BobA Brother of Bearded A http://flybase.net/reports/FBgn0040487.html "FBgn0026561, FBgn0040808" protein_coding_gene 0005515=protein binding "0001708=cell fate specification, 0042742=defense response to bacterium, 0016360=sensory organ precursor cell fate determination, 0007219=Notch signaling pathway, 0007423=sensory organ development" "Brother of Bearded, brother of bearded, CG12487, bobA, Bob, Bob-A" CG12487 16-Dec-15 2015_12 "viable,fertile,visible,lethal" "macrochaeta,microchaeta,external sensory organ precursor cell & dorsal mesothoracic disc-537.4,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,tormogen cell,trichogen cell" FBgn0011660 Pms2 Pms2 http://flybase.net/reports/FBgn0011660.html FBgn0024325 protein_coding_gene "0016887=ATPase activity, 0032407=MutSalpha complex binding, 0030983=mismatched DNA binding, 0005524=ATP binding, 0003697=single-stranded DNA binding" "0007131=reciprocal meiotic recombination, 0006298=mismatch repair" "0032300=mismatch repair complex, 0032389=MutLalpha complex, 0005875=microtubule associated complex" "dmlh-2, dpms2, CG8169, pms2, Mlh2, dmlh2" "IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR003594=Histidine kinase-like ATPase, C-terminal domain, IPR002099=DNA mismatch repair protein family, IPR014762=DNA mismatch repair, conserved site, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR028831=DNA mismatch repair protein Pms1/Pms2, IPR013507=DNA mismatch repair protein, C-terminal, IPR014790=MutL, C-terminal, dimerisation" CG8169 16-Dec-15 2015_12 ENSDARG00000000476(pms1) YNL082W(PMS1) WBGene00004064(pms-2) ENSXETG00000024066() ENSMUSG00000079109(Pms2) ENSG00000122512(PMS2) viable FBgn0267044 CG45488 http://flybase.net/reports/FBgn0267044.html protein_coding_gene CG45488 16-Dec-15 2015_12 FBgn0031873 Gas41 Gas41 http://flybase.net/reports/FBgn0031873.html protein_coding_gene "0016573=histone acetylation, 0006355=regulation of transcription, DNA-templated, 0006367=transcription initiation from RNA polymerase II promoter, 0043486=histone exchange" "0035267=NuA4 histone acetyltransferase complex, 0000123=histone acetyltransferase complex, 0005669=transcription factor TFIID complex, 0005634=nucleus" "CG9207, GAS41, dGas41" IPR005033=YEATS CG9207 16-Dec-15 2015_12 ENSDARG00000045874(yeats4) YNL107W(YAF9) WBGene00001585(gfl-1) ENSXETG00000026783(yeats4) ENSMUSG00000020171(Yeats4) ENSG00000127337(YEATS4) viable FBgn0020608 anon-12Db anon-12Db http://flybase.net/reports/FBgn0020608.html gene D1 16-Dec-15 2015_12 FBgn0259332 C434.2 http://flybase.net/reports/FBgn0259332.html gene 16-Dec-15 2015_12 "visible,lethal" "wing vein,wing hair,chaeta" FBgn0032613 CG13283 http://flybase.net/reports/FBgn0032613.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR000718=Peptidase M13, IPR024079=Metallopeptidase, catalytic domain" CG13283 16-Dec-15 2015_12 viable FBgn0060357 l(3)S140713a lethal (3) S140713a http://flybase.net/reports/FBgn0060357.html gene 1407/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0005138 l(2)74i lethal (2) 74i http://flybase.net/reports/FBgn0005138.html gene 16-Dec-15 2015_12 lethal FBgn0037466 CG1965 http://flybase.net/reports/FBgn0037466.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0000398=mRNA splicing, via spliceosome, 0000390=spliceosomal complex disassembly" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0071008=U2-type post-mRNA release spliceosomal complex" "IPR028211=Pre-mRNA-splicing factor Ntr2, IPR022783=GC-rich sequence DNA-binding factor domain, IPR012890=GC-rich sequence DNA-binding factor" CG1965 16-Dec-15 2015_12 ENSDARG00000062361(zgc:158234) WBGene00009672(F43G9.12) ENSXETG00000007803() ENSMUSG00000022974(Gcfc1) ENSG00000159086(GCFC1) lethal FBgn0035718 CG14820 http://flybase.net/reports/FBgn0035718.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0005515=protein binding, 0008270=zinc ion binding" 0006508=proteolysis "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG14820 16-Dec-15 2015_12 "ENSDARG00000021339(cpa5),ENSDARG00000030915(cpa1),ENSDARG00000043722(cpa4),ENSDARG00000010146(cpa2)" "WBGene00020281(T06A4.1),WBGene00021213(Y18H1A.9)" ENSXETG00000008034() "ENSMUSG00000011463(Cpb1),ENSMUSG00000071553(Cpa2),ENSMUSG00000054446(Cpa1),ENSMUSG00000029788(Cpa5),ENSMUSG00000001865(Cpa3),ENSMUSG00000042501(Cpa6),ENSMUSG00000021999(Cpb2)" "ENSG00000158516(CPA2),ENSG00000091704(CPA1),ENSG00000158525(CPA5),ENSG00000153002(CPB1)" "partially lethal - majority die,some die during pupal stage" FBgn0035760 CG8607 http://flybase.net/reports/FBgn0035760.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR005137=Photosystem I BtpA, assembly, IPR013785=Aldolase-type TIM barrel, IPR011060=Ribulose-phosphate binding barrel" CG8607 16-Dec-15 2015_12 ENSDARG00000068410(zgc:162297) WBGene00044797(F13E9.13) ENSXETG00000025560(TEgg005n14.1) viable FBgn0052736 CG32736 http://flybase.net/reports/FBgn0052736.html "FBgn0040920, FBgn0040921, FBgn0062989" protein_coding_gene "CG14429, BcDNA:RE60462" IPR028183=Uncharacterised protein family UPF0640 CG32736 16-Dec-15 2015_12 ENSMUSG00000058351 ENSG00000168273(C3orf78) FBgn0065673 l(2)SH0678 lethal (2) SH0678 http://flybase.net/reports/FBgn0065673.html gene l(2)SH2 0678 16-Dec-15 2015_12 "lethal,recessive" FBgn0263262 spa3 http://flybase.net/reports/FBgn0263262.html gene "0008406=gonad development, 0007502=digestive tract mesoderm development" sparse SGPs 3 16-Dec-15 2015_12 "gonad,gonadal sheath proper primordium,visceral mesoderm" FBgn0070020 BG01020 BG01020 http://flybase.net/reports/FBgn0070020.html gene 16-Dec-15 2015_12 stress response defective FBgn0261581 CG42691 http://flybase.net/reports/FBgn0261581.html protein_coding_gene CG42691 16-Dec-15 2015_12 FBgn0060809 l(3)S054908 lethal (3) S054908 http://flybase.net/reports/FBgn0060809.html gene 0549/08 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0051032 CR31032 http://flybase.net/reports/FBgn0051032.html FBgn0063248 pseudogene_attribute "CG31032, BcDNA:GH15189" CR31032 16-Dec-15 2015_12 FBgn0036614 CG4925 http://flybase.net/reports/FBgn0036614.html protein_coding_gene 0004871=signal transducer activity CG4925 16-Dec-15 2015_12 ENSDARG00000061020(LOC557112) WBGene00013042(Y49E10.23) ENSMUSG00000035173(A630007B06Rik) ENSG00000165813(C10orf118) FBgn0011768 Fdh Formaldehyde dehydrogenase http://flybase.net/reports/FBgn0011768.html FBgn0002986 protein_coding_gene "0008270=zinc ion binding, 0051903=S-(hydroxymethyl)glutathione dehydrogenase activity, 0004022=alcohol dehydrogenase (NAD) activity, 0004552=octanol dehydrogenase activity, 0080007=S-nitrosoglutathione reductase activity" "0006069=ethanol oxidation, 0080164=regulation of nitric oxide metabolic process, 2000169=regulation of peptidyl-cysteine S-nitrosylation, 0006066=alcohol metabolic process, 0008542=visual learning" "formaldehyde dehydrogenase, ODH, Odh, gfd/odh, ADHX, ADHX_DROME, fdh, glutathione-dependent formaldehyde dehydrogenase, gfd, Octanol dehydrogenase, GSNOR, CG6598, octanol dehydrogenase, odh" "IPR002085=Alcohol dehydrogenase superfamily, zinc-type, IPR014183=Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase, IPR016040=NAD(P)-binding domain, IPR002328=Alcohol dehydrogenase, zinc-type, conserved site, IPR013154=Alcohol dehydrogenase, N-terminal, IPR011032=GroES-like, IPR013149=Alcohol dehydrogenase, C-terminal" CG6598 16-Dec-15 2015_12 "ENSDARG00000034618,ENSDARG00000068154" YDL168W(SFA1) "WBGene00019240(H24K24.3),WBGene00021747(Y50D4C.2)" ENSXETG00000009304(adh5) ENSMUSG00000028138(Adh5) ENSG00000197894(ADH5) larval stage--adult stage "memory defective,heat sensitive,electrophoretic variant,viable,fertile" FBgn0019909 afl autosomal female lethal http://flybase.net/reports/FBgn0019909.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0030004 CG10958 http://flybase.net/reports/FBgn0030004.html protein_coding_gene "IPR029440=Dynein regulatory complex protein 1, C-terminal" CG10958 16-Dec-15 2015_12 ENSDARG00000042182(si:dkey-65b13.6) ENSXETG00000003329(C2orf39) ENSMUSG00000073102(Gm1060) ENSG00000157856(CCDC164) viable FBgn0060746 l(3)S065312b lethal (3) S065312b http://flybase.net/reports/FBgn0060746.html gene 0653/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0037831 Cap-H2 Chromosome associated protein H2 http://flybase.net/reports/FBgn0037831.html protein_coding_gene "0003682=chromatin binding, 0005515=protein binding" "0007060=male meiosis chromosome segregation, 0006325=chromatin organization, 0051304=chromosome separation, 0051276=chromosome organization" 0000796=condensin complex "CAP-H2, CapH2, CG14685, dCap-H2, cap-H2" CG14685 16-Dec-15 2015_12 ENSXETG00000023090(TEgg019e13.1) "viable,fertile,meiotic cell cycle defective,male semi-fertile,male sterile" "spermatozoon,polytene chromosome & nurse cell,polytene chromosome & nurse cellExel6159),primary spermatocyte in meiotic prophase I,primary spermatocyte in meiotic anaphase I,polytene chromosome & larval salivary gland43B,polytene chromosome & larval salivary gland | conditional - heat sensitivehs.PB,polytene chromosome & larval salivary glandhs.PB,polytene chromosomehs.PU,embryonic/larval salivary gland | third instar larval stage,nuclear envelopehs.PU" FBgn0260741 CG3281 http://flybase.net/reports/FBgn0260741.html "FBgn0037967, FBgn0044626, FBgn0015343" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0046427=positive regulation of JAK-STAT cascade 0005634=nucleus "87A7-9/1, anon-WO0140519.243, anon-87Aa" "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG3281 16-Dec-15 2015_12 FBgn0030484 GstT4 Glutathione S transferase T4 http://flybase.net/reports/FBgn0030484.html protein_coding_gene 0004364=glutathione transferase activity 0005737=cytoplasm "GSTT4, GST-theta, CG1681, gstt4" "IPR004046=Glutathione S-transferase, C-terminal, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG1681 16-Dec-15 2015_12 "ENSDARG00000042428(gstt1a),ENSDARG00000017388(gstt1b)" "ENSXETG00000024924(BC087825.1),ENSXETG00000022358(TNeu058f17.1)" "ENSMUSG00000001663(Gstt1),ENSMUSG00000001665(Gstt3),ENSMUSG00000009093(Gstt4),ENSMUSG00000033318(Gstt2)" "ENSG00000184674(GSTT1),ENSG00000099984(GSTT2),ENSG00000133433(GSTT2B)" "viable,fertile" FBgn0005130 l(1)X2 lethal (1) X2 http://flybase.net/reports/FBgn0005130.html gene lethal (1) X ray induced 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,embryonic segment,mitotic cell cycle | gastrula stage" FBgn0000293 Cg42DE Collagen-like 42DE http://flybase.net/reports/FBgn0000293.html gene "Cg7, Collagen-like gene, DCg7" 16-Dec-15 2015_12 FBgn0065319 l(2)SH1919 lethal (2) SH1919 http://flybase.net/reports/FBgn0065319.html gene "SH1919, l(2)SH2 1919" 16-Dec-15 2015_12 "lethal,recessive" FBgn0024262 acd(2)5M7 auditory courtship defective 5M7 http://flybase.net/reports/FBgn0024262.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0275434 CR46266 http://flybase.net/reports/FBgn0275434.html non_protein_coding_gene CR46266 16-Dec-15 2015_12 FBgn0032341 Reps http://flybase.net/reports/FBgn0032341.html protein_coding_gene "0005509=calcium ion binding, 0005515=protein binding" "CG6192, REPS" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR000261=EH domain" CG6192 16-Dec-15 2015_12 ENSDARG00000002877(si:dkey-217m5.1) WBGene00012696(reps-1) "ENSXETG00000001110(REPS2),ENSXETG00000005123(reps1)" "ENSMUSG00000040855(Reps2),ENSMUSG00000019854(Reps1)" "ENSG00000135597(REPS1),ENSG00000169891(REPS2)" viable FBgn0051760 CG31760 http://flybase.net/reports/FBgn0051760.html "FBgn0032417, FBgn0032418, FBgn0063000" protein_coding_gene "0004930=G-protein coupled receptor activity, 0008066=glutamate receptor activity" 0007214=gamma-aminobutyric acid signaling pathway 0016021=integral component of membrane "CG17214, CG17215, BcDNA:RE52162" "IPR017978=GPCR, family 3, C-terminal" CG31760 16-Dec-15 2015_12 "viable,fertile" DRSC02590 K 0.711210242 -0.529050037 -1.223619393 -0.093090562 -0.324758179 2.060973629 FBgn0034985 CG3328 http://flybase.net/reports/FBgn0034985.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated" "IPR008967=p53-like transcription factor, DNA-binding, IPR024061=NDT80 DNA-binding domain, IPR030392=Intramolecular chaperone auto-processing domain, IPR026932=Myelin gene regulatory factor C-terminal domain 1" CG3328 16-Dec-15 2015_12 "WBGene00004134(pqn-47),WBGene00008999(F21A10.2)" ENSXETG00000006702(C11orf9) ENSG00000124920(C11orf9) "viable,fertile" FBgn0044401 Scim26 Sensitized chromosome inheritance modifier 26 http://flybase.net/reports/FBgn0044401.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0266200 CR44895 http://flybase.net/reports/FBgn0266200.html non_protein_coding_gene CR44895 16-Dec-15 2015_12 FBgn0000406 Cyt-b5-r Cytochrome b5-related http://flybase.net/reports/FBgn0000406.html protein_coding_gene "0016491=oxidoreductase activity, 0020037=heme binding, 0009055=electron carrier activity" 0006629=lipid metabolic process "0016021=integral component of membrane, 0005739=mitochondrion, 0005811=lipid particle" "Cytb5r, Cyt-b, Cytb, TU-36B, TU36B, Cyt-b5, CG13279, Cytb5" "IPR005804=Fatty acid desaturase domain, IPR001199=Cytochrome b5-like heme/steroid binding domain, IPR018506=Cytochrome b5, heme-binding site, IPR012171=Fatty acid desaturase" CG13279 16-Dec-15 2015_12 "ENSMUSG00000075217(4833423E24Rik),ENSMUSG00000010663(Fads1),ENSMUSG00000024665(Fads2),ENSMUSG00000024664(Fads3)" "ENSG00000149485(FADS1),ENSG00000221968(FADS3),ENSG00000134824(FADS2),ENSG00000214876" " embryonic stage | stage 16 , pupal stage | late , larval stage&&adult stage " " larval visceral muscle

, tergosternal muscle

, skeletal muscle of leg

, embryonic/larval somatic muscle

" viable FBgn0003535 stop stopped http://flybase.net/reports/FBgn0003535.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0034381 List Lithium-inducible SLC6 transporter http://flybase.net/reports/FBgn0034381.html protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005416=cation:amino acid symporter activity, 0017032=potassium:amino acid symporter activity, 0005326=neurotransmitter transporter activity" "0044745=amino acid transmembrane import, 0010226=response to lithium ion, 0006836=neurotransmitter transport" 0016021=integral component of membrane "Lithium-inducible SLC6 transporter, DmNAT2, CG15088" IPR000175=Sodium:neurotransmitter symporter CG15088 16-Dec-15 2015_12 "chemical sensitive,partially lethal - majority die,some die during pupal stage" FBgn0052826 tRNA:CR32826 transfer RNA:CR32826 http://flybase.net/reports/FBgn0052826.html FBgn0060115 tRNA_gene 0033424=CCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR32826, AE002611.trna1-ProCGG, chrX.trna15-ProCGG, tRNA:P:CGG:AE002611" CR32826 16-Dec-15 2015_12 FBgn0030605 ND-B18 NADH dehydrogenase (ubiquinone) B18 subunit http://flybase.net/reports/FBgn0030605.html protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH-ubiquinone oxidoreductase B18 subunit, NADH ubiquinone oxidoreductase B18, NB8M, CG5548, NADH:ubiquinone oxidoreductase B18 subunit" "IPR008698=NADH:ubiquinone oxidoreductase, B18 subunit" CG5548 16-Dec-15 2015_12 ENSDARG00000033789(zgc:77820) WBGene00008414(D2030.4) ENSXETG00000025316(NDUFB7) ENSMUSG00000033938(Ndufb7) ENSG00000099795(NDUFB7) "visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0267899 CR46187 http://flybase.net/reports/FBgn0267899.html pseudogene_attribute CG12717-related CR46187 16-Dec-15 2015_12 FBgn0037255 Fip1 http://flybase.net/reports/FBgn0037255.html "FBan0001078, FBgn0025996" protein_coding_gene 0017022=myosin binding "0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction, 0006398=histone mRNA 3'-end processing" 0005634=nucleus "anon-EST:Liang-1.35, clone 1.35, CG1078, FIP1, dFip1" "IPR007854=Pre-mRNA polyadenylation factor Fip1, IPR002713=FF domain" CG1078 16-Dec-15 2015_12 "ENSDARG00000070431(fip1l1),ENSDARG00000043328(si:dkey-161n17.1)" WBGene00017988(fipp-1) ENSXETG00000011679(fip1l1) ENSMUSG00000029227(Fip1l1) ENSG00000145216(FIP1L1) "lethal,viable" embryonic/larval brain DRSC12147 K 0.024469664 0.893397531 -0.60381522 -0.264861956 -2.183820967 -0.282578402 FBgn0036311 CG17666 http://flybase.net/reports/FBgn0036311.html protein_coding_gene bs31g10.y1 CG17666 16-Dec-15 2015_12 viable FBgn0003078 Ppb Photophobe http://flybase.net/reports/FBgn0003078.html gene Phb 16-Dec-15 2015_12 FBgn0265994 CR44769 http://flybase.net/reports/FBgn0265994.html non_protein_coding_gene lincRNA.187 CR44769 16-Dec-15 2015_12 FBgn0261611 CG42700 http://flybase.net/reports/FBgn0261611.html "FBgn0033707, FBgn0085262" protein_coding_gene "CG13165, CG34233, ORE-16" CG42700 16-Dec-15 2015_12 FBgn0061162 l(1)6C-166 lethal (1) 6C-166 http://flybase.net/reports/FBgn0061162.html gene 6C-166 16-Dec-15 2015_12 "lethal,recessive" FBgn0262811 CG43182 http://flybase.net/reports/FBgn0262811.html protein_coding_gene CG43182 16-Dec-15 2015_12 FBgn0003584 su(t) suppressor of tan http://flybase.net/reports/FBgn0003584.html gene 16-Dec-15 2015_12 FBgn0260274 GSd486 http://flybase.net/reports/FBgn0260274.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038131 CG15888 http://flybase.net/reports/FBgn0038131.html protein_coding_gene CG15888 16-Dec-15 2015_12 lethal FBgn0261723 Dbx Dbx http://flybase.net/reports/FBgn0261723.html "FBgn0062390, FBgn0250756, FBgn0035291, FBgn0035292" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0007411=axon guidance, 0048663=neuron fate commitment" 0005634=nucleus "CG12361, dDbx, CG42234, CG13925, dbx" "IPR000047=Helix-turn-helix motif, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG42234 16-Dec-15 2015_12 DRSC08271 K -0.30386415 0.964323143 -0.33257532 0.319406664 2.870977665 0.982165077 FBgn0262073 JC11 http://flybase.net/reports/FBgn0262073.html gene 0072347=response to anesthetic 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0003289 Rst(3)amd ë± methyl dopa-resistant on 3 http://flybase.net/reports/FBgn0003289.html FBgn0004948 gene "alpha methyl dopa-resistant dominant, Amdr, Resistance (3) alpha methyl dopa" 16-Dec-15 2015_12 "lethal,recessive,chemical resistant,dominant" FBgn0067044 U14 U14 http://flybase.net/reports/FBgn0067044.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal" "chaeta,pigment cell" FBgn0032860 CG15130 http://flybase.net/reports/FBgn0032860.html protein_coding_gene 38C.48 CG15130 16-Dec-15 2015_12 WBGene00012662(Y39A1C.1) viable FBgn0266784 CR45249 http://flybase.net/reports/FBgn0266784.html non_protein_coding_gene CR45249 16-Dec-15 2015_12 FBgn0001420 l(1)6Dd lethal (1) 6Dd http://flybase.net/reports/FBgn0001420.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003074 Pgi Phosphoglucose isomerase http://flybase.net/reports/FBgn0003074.html protein_coding_gene "0004616=phosphogluconate dehydrogenase (decarboxylating) activity, 0004347=glucose-6-phosphate isomerase activity" "0006096=glycolytic process, 0006094=gluconeogenesis" "0005737=cytoplasm, 0005811=lipid particle" "Gpi, phosphoglucoisomerase, phosphoglucose isomerase, pgi, CG8251, glucose phosphate isomerase, GPI, PGI" "IPR023096=Phosphoglucose isomerase, C-terminal, IPR001672=Phosphoglucose isomerase (PGI), IPR018189=Phosphoglucose isomerase, conserved site" CG8251 16-Dec-15 2015_12 "ENSDARG00000012987(gpia),ENSDARG00000005161(gpib)" YBR196C(PGI1) WBGene00013597(gpi-1) ENSXETG00000002361(Q640A7_XENTR) ENSMUSG00000036427(Gpi1) ENSG00000105220(GPI) "electrophoretic variant,slow,viable,fertile,lethal,recessive" FBgn0003482 spn-D spindle D http://flybase.net/reports/FBgn0003482.html "FBgn0047153, FBgn0051069" protein_coding_gene "0005524=ATP binding, 0003677=DNA binding, 0008094=DNA-dependent ATPase activity" "0009994=oocyte differentiation, 0008298=intracellular mRNA localization, 0031023=microtubule organizing center organization, 0009951=polarity specification of dorsal/ventral axis, 0030717=karyosome formation, 0007294=germarium-derived oocyte fate determination, 0006281=DNA repair, 0009949=polarity specification of anterior/posterior axis, 0046843=dorsal appendage formation, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0007131=reciprocal meiotic recombination, 0048477=oogenesis" "spnD, Spindle D, BcDNA:RE19845, spndD, rad51C, CG31069, Spn-D" "IPR020588=DNA recombination and repair protein RecA-like, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013632=DNA recombination and repair protein Rad51, C-terminal" CG31069 16-Dec-15 2015_12 ENSDARG00000068919(rad51c) ENSXETG00000001122(rad51c) ENSMUSG00000007646(Rad51c) ENSG00000108384(RAD51C) adult stage | female ovary

"viable,fertile,lethal" "chorion | maternal effect,karyosome,egg,dorsal,dorsal appendage,oocyte,nurse cell,synaptonemal complex,germline cyst,microtubule organizing center & oocyte,presumptive oocyte" FBgn0025393 CG14795 http://flybase.net/reports/FBgn0025393.html protein_coding_gene EG:196F3.3 CG14795 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005232 l(3)R26 lethal of Roberts 26 http://flybase.net/reports/FBgn0005232.html gene l(3)26 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0037280 CG1126 http://flybase.net/reports/FBgn0037280.html protein_coding_gene 0032266=phosphatidylinositol-3-phosphate binding 0042384=cilium assembly 0034464=BBSome BBS5 "IPR006606=Bardet-Biedl syndrome 5 protein, IPR030804=Bardet-Biedl syndrome 5 protein/sex-determination protein fem-3, IPR014003=DM16 repeat" CG1126 16-Dec-15 2015_12 ENSDARG00000039827(bbs5) WBGene00010974(bbs-5) ENSXETG00000018935() ENSMUSG00000063145(Bbs5) ENSG00000163093(BBS5) viable DRSC12168 E 0.649027914 0.578822865 -1.670328423 0.470314141 0.340752514 0.129257066 FBgn0029184 E(Khc)ek2 E(Khc)ek2 http://flybase.net/reports/FBgn0029184.html gene 16-Dec-15 2015_12 FBgn0030443 CG12715 http://flybase.net/reports/FBgn0030443.html protein_coding_gene IPR008166=Glycosyltransferase family 92 CG12715 16-Dec-15 2015_12 ENSDARG00000053345(LOC100334791) "ENSXETG00000026707(),ENSXETG00000026391()" viable FBgn0032848 nesd nessun dorma http://flybase.net/reports/FBgn0032848.html protein_coding_gene 0030246=carbohydrate binding "0007112=male meiosis cytokinesis, 0008335=female germline ring canal stabilization" "0035323=male germline ring canal, 0035324=female germline ring canal, 0030496=midbody, 0045171=intercellular bridge, 0045169=fusome" "38B.16, CG10722, Nessun Dorma" IPR011050=Pectin lyase fold/virulence factor CG10722 16-Dec-15 2015_12 ENSDARG00000052167(shcbp1) ENSXETG00000017069(TGas091j04.1) "ENSMUSG00000022322(Shcbp1),ENSMUSG00000042708(1700012A16Rik)" "ENSG00000171241(SHCBP1),ENSG00000157060(SHCBP1L)" "viable,fertile,male semi-sterile,meiotic cell cycle defective,partially lethal - majority die" "onion stage spermatid,Nebenkern,contractile ring,cleavage furrow,spermatocyte ring canal,nurse cell ring canal,nurse cell" FBgn0065114 mfs(1)6E male-female-sterile in region 6E http://flybase.net/reports/FBgn0065114.html gene "0046008=regulation of female receptivity, post-mating, 0046693=sperm storage" 16-Dec-15 2015_12 "male sterile,recessive,female sterile" "male accessory gland,male accessory gland main cell" FBgn0035028 Start1 Start1 http://flybase.net/reports/FBgn0035028.html protein_coding_gene "0017127=cholesterol transporter activity, 0015485=cholesterol binding" "StART1, Start, start1, CG3522" "IPR019498=MENTAL domain, IPR002913=START domain, IPR000799=Steroidogenic acute regulatory protein-like, IPR023393=START-like domain" CG3522 16-Dec-15 2015_12 ENSDARG00000017809(stard3) WBGene00017826(tag-340) ENSXETG00000015141(STARD3) ENSMUSG00000018167(Stard3) ENSG00000131748(STARD3) viable FBgn0265918 CR44707 http://flybase.net/reports/FBgn0265918.html non_protein_coding_gene lincRNA.1015 CR44707 16-Dec-15 2015_12 FBgn0046678 anon-38C.15 anon-38C.15 http://flybase.net/reports/FBgn0046678.html gene 38C.15 16-Dec-15 2015_12 FBgn0263656 CG43647 http://flybase.net/reports/FBgn0263656.html protein_coding_gene "lincRNA.258, mlncRNA42E5-1" CG43647 16-Dec-15 2015_12 FBgn0058005 CR40005 http://flybase.net/reports/FBgn0058005.html FBan0040005 pseudogene_attribute "0003924=GTPase activity, 0031683=G-protein beta/gamma-subunit complex binding, 0031752=D5 dopamine receptor binding, 0004871=signal transducer activity, 0005525=GTP binding" "0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway, 0007266=Rho protein signal transduction" "0031234=extrinsic component of cytoplasmic side of plasma membrane, 0005834=heterotrimeric G-protein complex, 0031526=brush border membrane" CG40005 "IPR000469=G-protein alpha subunit, group 12, IPR011025=G protein alpha subunit, helical insertion, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit" CR40005 16-Dec-15 2015_12 "ENSDARG00000037924(gna13b),ENSDARG00000025826(gna12)" WBGene00001674(gpa-12) ENSXETG00000001253(GNA13) "ENSMUSG00000020611(Gna13),ENSMUSG00000000149(Gna12)" "ENSG00000120063(GNA13),ENSG00000146535(GNA12)" FBgn0028856 CG18063 http://flybase.net/reports/FBgn0028856.html FBgn0032579 protein_coding_gene 0032027=myosin light chain binding "BG:DS07486.5, DS07486.5" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000048=IQ motif, EF-hand binding site" CG18063 16-Dec-15 2015_12 viable FBgn0040546 CG14705 http://flybase.net/reports/FBgn0040546.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001415 l(1)3Ee lethal (1) 3Ee http://flybase.net/reports/FBgn0001415.html gene l(1)RC245 16-Dec-15 2015_12 lethal FBgn0067729 l(3)J1 lethal (3) J1 http://flybase.net/reports/FBgn0067729.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083008 snoRNA:ë¬28S-1135e snoRNA:ë¬28S-1135e http://flybase.net/reports/FBgn0083008.html snoRNA_gene "Psi28S-1135e, psi28S-1135e, CR34601, chrX:16979721..16979820" CR34601 16-Dec-15 2015_12 FBgn0050058 CG30058 http://flybase.net/reports/FBgn0050058.html FBan0030058 protein_coding_gene CG30058 16-Dec-15 2015_12 FBgn0051230 CG31230 http://flybase.net/reports/FBgn0051230.html protein_coding_gene CG31230 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0259183 CG42287 http://flybase.net/reports/FBgn0259183.html "FBan0013353, FBgn0033896" protein_coding_gene CG13353 CG42287 16-Dec-15 2015_12 FBgn0036330 CG11263 http://flybase.net/reports/FBgn0036330.html protein_coding_gene 0003676=nucleic acid binding IPR012337=Ribonuclease H-like domain CG11263 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0060534 l(3)S100513 lethal (3) S100513 http://flybase.net/reports/FBgn0060534.html gene 1005/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0017427 anon-68Ea anon-68Ea http://flybase.net/reports/FBgn0017427.html gene T1 16-Dec-15 2015_12 FBgn0025157 ms(2)A10 ms(2)A10 http://flybase.net/reports/FBgn0025157.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0262712 ifm(2)RS5 http://flybase.net/reports/FBgn0262712.html gene "0060361=flight, 0007527=adult somatic muscle development" 16-Dec-15 2015_12 "flightless,recessive" dorsal medial muscle FBgn0050212 tRNA:CR30212 transfer RNA:CR30212 http://flybase.net/reports/FBgn0050212.html "FBgn0050133, FBgn0060086" tRNA_gene 0033448=AGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR30133, AE002787.trna2-ArgCCT, chr2R.trna60-ArgCCT, CR30212, tRNA:R:CCT:AE002787-a" CR30212 16-Dec-15 2015_12 FBgn0005272 l(3)SG92 lethal (3) SG92 http://flybase.net/reports/FBgn0005272.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031126 Cyp6v1 Cyp6v1 http://flybase.net/reports/FBgn0031126.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG1829, 6v1, cytochrome P450" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG1829 16-Dec-15 2015_12 "ENSDARG00000037874(LOC558473),ENSDARG00000037873(cyp3c1l2),ENSDARG00000070021(zgc:153269),ENSDARG00000015575(cyp3c1)" YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "viable,fertile" FBgn0000225 Bsb Blunt short bristle http://flybase.net/reports/FBgn0000225.html gene 0048800=antennal morphogenesis 16-Dec-15 2015_12 "visible,dominant,lethal,recessive,viable,fertile" "macrochaeta,arista,arista lateral,actin filament & arista,microtubule & arista" FBgn0015922 cln clown http://flybase.net/reports/FBgn0015922.html gene "0001745=compound eye morphogenesis, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0042675=compound eye cone cell differentiation" 16-Dec-15 2015_12 "viable,eye color defective,recessive,visible,fertile,female fertile,male fertile" "eye,ommatidium,pigment cell,secondary pigment cell,ectopic,tertiary pigment cell,cone cell,eye disc & photoreceptor cell,photoreceptor cell,lens,dorsal compartment" FBgn0029864 CG15894 http://flybase.net/reports/FBgn0029864.html protein_coding_gene CG15894 16-Dec-15 2015_12 "viable,fertile" FBgn0040705 ND-B8 NADH dehydrogenase (ubiquinone) B8 subunit http://flybase.net/reports/FBgn0040705.html protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "CG15434, NI8M, NADH-ubiquinone oxidoreductase B8 subunit, NADH ubiquinone oxidoreductase B8, NADH:ubiquinone oxidoreductase B8 subunit" "IPR007741=Ribosomal protein/NADH dehydrogenase domain, IPR016464=NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2, IPR012336=Thioredoxin-like fold" CG15434 16-Dec-15 2015_12 ENSDARG00000021984(zgc:112340) WBGene00013406(Y63D3A.7) ENSXETG00000027693(NDUFA2) ENSMUSG00000014294(Ndufa2) ENSG00000131495(NDUFA2) "viable,visible,planar polarity defective" mesothoracic tergum FBgn0264698 CR43967 http://flybase.net/reports/FBgn0264698.html non_protein_coding_gene CR43967 16-Dec-15 2015_12 FBgn0013910 Dtf-1 Dtf-1 http://flybase.net/reports/FBgn0013910.html gene 0005634=nucleus DTF-1 16-Dec-15 2015_12 FBgn0025160 l(2)GA339 lethal (2) GA339 http://flybase.net/reports/FBgn0025160.html gene GA339 16-Dec-15 2015_12 "lethal,recessive" ganglion mother cell GMC4-2a FBgn0262105 CR42858 http://flybase.net/reports/FBgn0262105.html non_protein_coding_gene CR42858 16-Dec-15 2015_12 FBgn0053483 CG33483 http://flybase.net/reports/FBgn0053483.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG33483 16-Dec-15 2015_12 FBgn0260366 GSd234 http://flybase.net/reports/FBgn0260366.html gene 16-Dec-15 2015_12 lethal FBgn0011659 Mlh1 Mlh1 http://flybase.net/reports/FBgn0011659.html protein_coding_gene "0003697=single-stranded DNA binding, 0005524=ATP binding, 0016887=ATPase activity, 0030983=mismatched DNA binding, 0032407=MutSalpha complex binding" "0007131=reciprocal meiotic recombination, 0006298=mismatch repair" "0032390=MutLbeta complex, 0000795=synaptonemal complex, 0032300=mismatch repair complex, 0005712=chiasma, 0032389=MutLalpha complex" "dmlh-1, dmlh1, CG11482" "IPR011186=DNA mismatch repair protein Mlh1/HexB, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR013507=DNA mismatch repair protein, C-terminal, IPR014762=DNA mismatch repair, conserved site, IPR002099=DNA mismatch repair protein family, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR003594=Histidine kinase-like ATPase, C-terminal domain" CG11482 16-Dec-15 2015_12 ENSDARG00000025948(mlh1) YMR167W(MLH1) WBGene00003373(mlh-1) ENSXETG00000004985() ENSMUSG00000032498(Mlh1) ENSG00000076242(MLH1) viable FBgn0052745 CR32745 http://flybase.net/reports/FBgn0052745.html pseudogene_attribute CG32745 CR32745 16-Dec-15 2015_12 FBgn0037513 pyd3 pyd3 http://flybase.net/reports/FBgn0037513.html protein_coding_gene 0003837=beta-ureidopropionase activity "0006207='de novo' pyrimidine nucleobase biosynthetic process, 0006208=pyrimidine nucleobase catabolic process" "beta-Alanine synthase, CG3027, betaASase, betaAS, beta-alanine synthase" IPR003010=Carbon-nitrogen hydrolase CG3027 16-Dec-15 2015_12 ENSDARG00000011521(upb1) WBGene00017440(F13H8.7) ENSXETG00000004225(UPB1) ENSMUSG00000033427(Upb1) ENSG00000100024(UPB1) "viable,fertile" FBgn0263133 ico iconoclast http://flybase.net/reports/FBgn0263133.html "FBgn0243517, FBgn0031898, FBgn0084839, FBgn0001951, FBgn0001947" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003746=translation elongation factor activity" "0070125=mitochondrial translational elongation, 0006414=translational elongation" "0005634=nucleus, 0005739=mitochondrion" "B, lethal (2) 27Cb, GFM1, l(2)27Cb, Complementation group G, CG4567, l(2)27Ea, lethal (2) 27Ea, dEF-G1, Complementation group B, G" "IPR004540=Translation elongation factor EFG/EF2, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR005225=Small GTP-binding protein domain, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR031157=Tr-type G domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000640=Translation elongation factor EFG, V domain, IPR005517=Translation elongation factor EFG/EF2, domain IV, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR009022=Elongation factor G, III-V domain, IPR020568=Ribosomal protein S5 domain 2-type fold" CG4567 16-Dec-15 2015_12 ENSDARG00000063624(zgc:154041) YLR069C(MEF1) WBGene00009246(F29C12.4) ENSMUSG00000027774(Gfm1) ENSG00000168827(GFM1) FBgn0050108 CG30108 http://flybase.net/reports/FBgn0050108.html protein_coding_gene IPR007918=Mitochondrial distribution/morphology family 35/apoptosis CG30108 16-Dec-15 2015_12 ENSDARG00000014963(zgc:112025) YKL053C-A(MDM35) WBGene00011635(T09A5.7) ENSXETG00000012223(TRIAP1) ENSMUSG00000029535(Triap1) ENSG00000170855(TRIAP1) "viable,fertile" FBgn0262114 RanBPM Ran-binding protein M http://flybase.net/reports/FBgn0262114.html "FBgn0033522, FBgn0250861, FBgn0022187" protein_coding_gene 0008536=Ran GTPase binding "0007299=ovarian follicle cell-cell adhesion, 0060250=germ-line stem-cell niche homeostasis, 0030536=larval feeding behavior, 0046843=dorsal appendage formation, 0007259=JAK-STAT cascade, 0007010=cytoskeleton organization" 0005737=cytoplasm "lethal (2) k05201, Ran-Binding Protein in the Microtubule Organizing Center, Ran binding protein M, CG11763, CG42236, l(2)k05201, Ran-binding proteins 9/10 homologue" "IPR024964=CTLH/CRA C-terminal to LisH motif domain, IPR013144=CRA domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR006595=CTLH, C-terminal LisH motif, IPR006594=LIS1 homology motif, IPR001870=B30.2/SPRY domain, IPR003877=SPRY domain" CG42236 16-Dec-15 2015_12 "ENSDARG00000061048(ranbp9),ENSDARG00000062138(ranbp10)" YGL227W(VID30) ENSXETG00000002271(ranbp10) "ENSMUSG00000038546(Ranbp9),ENSMUSG00000037415(Ranbp10)" "ENSG00000010017(RANBP9),ENSG00000141084(RANBP10)" FBgn0026165 schmalspur schmalspur http://flybase.net/reports/FBgn0026165.html gene 0007417=central nervous system development sur 16-Dec-15 2015_12 "commissure,midline glial cell,presumptive embryonic/larval central nervous system,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0266651 CR45158 http://flybase.net/reports/FBgn0266651.html non_protein_coding_gene CR45158 16-Dec-15 2015_12 FBgn0266220 CR44915 http://flybase.net/reports/FBgn0266220.html non_protein_coding_gene CR44915 16-Dec-15 2015_12 FBgn0025107 Brg-P9 Brg-P9 http://flybase.net/reports/FBgn0025107.html gene 16-Dec-15 2015_12 FBgn0069334 UY4766 UY4766 http://flybase.net/reports/FBgn0069334.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body gamma-lobe" FBgn0262372 mir-3 mir-3 stem loop http://flybase.net/reports/FBgn0262372.html "FBgn0046822, FBgn0262183" miRNA_gene "3, CR33037, mir-3, miR-3, CR42890" CR42890 16-Dec-15 2015_12 embryonic stage | 0-12 hr "viable,lethal,lethal - all die before end of pupal stage,some die during pupal stage" wing FBgn0039558 BCAS2 BCAS2 ortholog http://flybase.net/reports/FBgn0039558.html protein_coding_gene 0005515=protein binding "0006397=mRNA processing, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005681=spliceosomal complex, 0000974=Prp19 complex, 0071013=catalytic step 2 spliceosome" "dBCAS2, CG4980" IPR008409=Pre-mRNA-splicing factor SPF27 CG4980 16-Dec-15 2015_12 ENSDARG00000043631(bcas2) WBGene00020441(T12A2.7) ENSXETG00000020352(bcas2) ENSMUSG00000005687(Bcas2) ENSG00000116752(BCAS2) "viable,visible,body color defective,increased cell death,lethal" "trichogen cell,mesothoracic tergum,wing,scutellum,chaeta,wing disc,posterior compartment" FBgn0058165 CG40165 http://flybase.net/reports/FBgn0058165.html protein_coding_gene 16-Dec-15 2015_12 FBgn0259345 EP-990 http://flybase.net/reports/FBgn0259345.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta,ectopic" FBgn0044389 Scim5 Sensitized chromosome inheritance modifier 5 http://flybase.net/reports/FBgn0044389.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0022344 CG10340 http://flybase.net/reports/FBgn0022344.html protein_coding_gene 0006461=protein complex assembly 0005739=mitochondrion "unnamed, anon-fast-evolving-2A5, anon2A5, anon-EST:fe2A5" IPR010591=ATP11 CG10340 16-Dec-15 2015_12 ENSDARG00000042799(si:dkey-171o17.2) YNL315C(ATP11) ENSXETG00000024499(atpaf1) ENSMUSG00000028710(Atpaf1) ENSG00000123472(ATPAF1) "viable,fertile" FBgn0085786 CR41501 http://flybase.net/reports/FBgn0085786.html FBan0041501 pseudogene_attribute CR41501 16-Dec-15 2015_12 FBgn0037879 scpr-C SCP-containing protein C http://flybase.net/reports/FBgn0037879.html FBgn0045838 protein_coding_gene 0005576=extracellular region "Scpr-C, SCP-Related-C, BEST:CK01680, scp-C, CG5106, cg5106, SCPR-C" "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG5106 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0034863 SkpF SKP1-related F http://flybase.net/reports/FBgn0034863.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process "0000152=nuclear ubiquitin ligase complex, 0019005=SCF ubiquitin ligase complex" "Skp, SkpF, CG12227, skpF" "IPR016073=SKP1 component, POZ domain, IPR001232=S-phase kinase-associated protein 1-like, IPR016072=SKP1 component, dimerisation, IPR016897=S-phase kinase-associated protein 1, IPR011333=POZ domain" CG12227 16-Dec-15 2015_12 YDR328C(SKP1) FBgn0063388 snoRNA:U27:54Ea snoRNA:U27:54Ea http://flybase.net/reports/FBgn0063388.html snoRNA_gene "CR32892, U27snoRNA" CR32892 16-Dec-15 2015_12 FBgn0005725 l(1)TK135 lethal (1) TK135 http://flybase.net/reports/FBgn0005725.html gene l135 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259566 GG01373 http://flybase.net/reports/FBgn0259566.html gene 16-Dec-15 2015_12 visible "antennal segment,wing" FBgn0004754 l(3)89Bg lethal (3) 89Bg http://flybase.net/reports/FBgn0004754.html gene 16-Dec-15 2015_12 lethal FBgn0021928 l(2)k11118 lethal (2) k11118 http://flybase.net/reports/FBgn0021928.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265496 CR44365 http://flybase.net/reports/FBgn0265496.html non_protein_coding_gene lincRNA.303 CR44365 16-Dec-15 2015_12 FBgn0065476 l(2)SH1305 lethal (2) SH1305 http://flybase.net/reports/FBgn0065476.html gene l(2)SH2 1305 16-Dec-15 2015_12 "lethal,recessive" FBgn0032361 CG6488 http://flybase.net/reports/FBgn0032361.html protein_coding_gene 0017119=Golgi transport complex "IPR016159=Cullin repeat-like-containing domain, IPR016632=Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae, IPR007255=Conserved oligomeric Golgi complex subunit 8" CG6488 16-Dec-15 2015_12 ENSDARG00000002798(cog8) WBGene00019820(cogc-8) ENSXETG00000017851(COG8) ENSMUSG00000031916(Cog8) ENSG00000213380(COG8) "viable,fertile" FBgn0060673 l(3)S077801 lethal (3) S077801 http://flybase.net/reports/FBgn0060673.html gene 0778/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0061167 l(1)20BC lethal (1) 20BC http://flybase.net/reports/FBgn0061167.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002475 l(3)SG30 lethal (3) SG30 http://flybase.net/reports/FBgn0002475.html gene SG30 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye-antennal disc FBgn0085453 CG34424 http://flybase.net/reports/FBgn0085453.html FBgn0034851 protein_coding_gene 0030272=5-formyltetrahydrofolate cyclo-ligase activity 0005829=cytosol "anon-WO0118547.139, CG11079" "IPR002698=5-formyltetrahydrofolate cyclo-ligase, IPR024185=5-formyltetrahydrofolate cyclo-ligase-like domain" CG34424 16-Dec-15 2015_12 ENSDARG00000042465(LOC100332843) YER183C(FAU1) WBGene00013708(Y106G6E.4) ENSXETG00000024293(MTHFS) "ENSMUSG00000079427(Gm2382),ENSMUSG00000066442(Mthfs)" ENSG00000136371(MTHFS) viable FBgn0065505 l(2)SH1197 lethal (2) SH1197 http://flybase.net/reports/FBgn0065505.html gene l(2)SH2 1197 16-Dec-15 2015_12 "lethal,recessive" FBgn0021901 l(2)k12408 lethal (2) k12408 http://flybase.net/reports/FBgn0021901.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030052 CG12065 http://flybase.net/reports/FBgn0030052.html protein_coding_gene 0003824=catalytic activity "0009116=nucleoside metabolic process, 0046331=lateral inhibition" "IPR018017=Nucleoside phosphorylase, IPR000845=Nucleoside phosphorylase domain" CG12065 16-Dec-15 2015_12 WBGene00019199(H14E04.2) "viable,fertile,visible" "chaeta,supernumerary" FBgn0264282 Su(Mir)3C2-1 http://flybase.net/reports/FBgn0264282.html gene 16-Dec-15 2015_12 lethal FBgn0053100 4EHP eIF4E-Homologous Protein http://flybase.net/reports/FBgn0053100.html FBgn0039148 protein_coding_gene "0005515=protein binding, 0030371=translation repressor activity, 0000340=RNA 7-methylguanosine cap binding, 0031370=eukaryotic initiation factor 4G binding, 0003743=translation initiation factor activity" "0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior, 0006413=translational initiation, 0022008=neurogenesis, 0017148=negative regulation of translation" 0005737=cytoplasm "CT30033, CG10716, eIF4E-8, d4EHP, 4EHP, CG33100, 4E-HP" "IPR001040=Translation Initiation factor eIF- 4e, IPR023398=Translation Initiation factor eIF- 4e-like" CG33100 16-Dec-15 2015_12 WBGene00002062(ife-4) "ENSXETG00000014992(TGas130a10.1),ENSXETG00000027885(EIF4E2)" ENSMUSG00000026254(Eif4e2) ENSG00000135930(EIF4E2) "viable,fertile,behavior defective,recessive,partially lethal - majority die,maternal effect,some die during embryonic stage,lethal,neuroanatomy defective,visible,some die during pupal stage" "embryonic head segment,maternal effect,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0265625 CG44433 http://flybase.net/reports/FBgn0265625.html FBgn0034374 protein_coding_gene CG15086 CG44433 16-Dec-15 2015_12 FBgn0260807 EP3-980 http://flybase.net/reports/FBgn0260807.html gene 16-Dec-15 2015_12 FBgn0004719 ads all discs small http://flybase.net/reports/FBgn0004719.html gene "l(3)ry100, l(3)ds16" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267617 CR45955 http://flybase.net/reports/FBgn0267617.html non_protein_coding_gene CR45955 16-Dec-15 2015_12 FBgn0023213 eIF4G eukaryotic translation initiation factor 4G http://flybase.net/reports/FBgn0023213.html protein_coding_gene "0008190=eukaryotic initiation factor 4E binding, 0003743=translation initiation factor activity, 0000340=RNA 7-methylguanosine cap binding, 0003723=RNA binding" "0007052=mitotic spindle organization, 0048137=spermatocyte division, 0007067=mitotic nuclear division, 0006413=translational initiation, 0048136=male germ-line cyst formation, 0000082=G1/S transition of mitotic cell cycle, 0048515=spermatid differentiation, 0006412=translation, 0007095=mitotic G2 DNA damage checkpoint, 0000022=mitotic spindle elongation" "0005829=cytosol, 0016281=eukaryotic translation initiation factor 4F complex" "translation initiation factor eIF4G, eIF4g, eIF4G, p200, EIF4G, CG10811, Eukaryotic initiation factor 4G, Eukaryotic-initiation-factor-4G, translation initiation factor, eukaryotic initiation factor 4G, deIF4G, eIF-4G, Eif4G" "IPR003890=MIF4G-like, type 3, IPR016024=Armadillo-type fold, IPR003891=Initiation factor eIF-4 gamma, MA3, IPR003307=W2 domain, IPR016021=MIF4G-like domain" CG10811 16-Dec-15 2015_12 ENSDARG00000006200(zgc:158450) "YGL049C(TIF4632),YGR162W(TIF4631)" ENSXETG00000009483(EIF4G3) "ENSMUSG00000045983(Eif4g1),ENSMUSG00000028760(Eif4g3)" "ENSG00000114867(EIF4G1),ENSG00000075151(EIF4G3)" lethal DRSC17218 IE 0.876038645 -2.069641687 -2.405192068 -1.40025058 -1.066382831 -0.527779547 FBgn0022265 l(2)k00611 lethal (2) k00611 http://flybase.net/reports/FBgn0022265.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000025 acj1 abnormal chemosensory jump 1 http://flybase.net/reports/FBgn0000025.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 FBgn0265212 fs(2)Z2-147 http://flybase.net/reports/FBgn0265212.html gene 16-Dec-15 2015_12 female sterile FBgn0010140 l(2)DTS486 lethal (2) DTS486 http://flybase.net/reports/FBgn0010140.html gene DTS486 16-Dec-15 2015_12 "lethal,dominant,partially,heat sensitive,female sterile" FBgn0031183 CG14621 http://flybase.net/reports/FBgn0031183.html protein_coding_gene 0008524=glucose 6-phosphate:phosphate antiporter activity "lincRNA.1043, Slc35e1" IPR004853=Sugar phosphate transporter domain CG14621 16-Dec-15 2015_12 ENSDARG00000011945(slc35e1) "YJL193W(),YOR307C(SLY41)" ENSXETG00000019945(SLC35E4) ENSMUSG00000019731(Slc35e1) ENSG00000127526(SLC35E1) viable FBgn0005025 dumpyoidy dumpyoidy http://flybase.net/reports/FBgn0005025.html gene dpy 16-Dec-15 2015_12 "visible,recessive" wing FBgn0031971 Sirup Starvation-upregulated protein http://flybase.net/reports/FBgn0031971.html "FBgn0027762, FBgn0063239, FBtr0079532, FBpp0079154" protein_coding_gene "starvation-upregulated protein, dSdhaf4, anon-EST:Posey12, BcDNA:GH18422, CG7224" IPR012875=Protein of unknown function DUF1674 CG7224 16-Dec-15 2015_12 ENSDARG00000039390(si:busm1-265n4.4) WBGene00020937(W02D3.12) ENSMUSG00000026154(1110058L19Rik) ENSG00000154079(C6orf57) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0047095 CG33939 putative noncoding RNA 004:X http://flybase.net/reports/FBgn0047095.html FBgn0053939 protein_coding_gene "CR33939, pncr004:X, BcDNA:RE54004" CG33939 16-Dec-15 2015_12 FBgn0015539 scs special chromatin structure http://flybase.net/reports/FBgn0015539.html insulator SCS 16-Dec-15 2015_12 FBgn0028544 CG16884 http://flybase.net/reports/FBgn0028544.html FBgn0027907 protein_coding_gene 0035220=wing disc development "vajk-3, BG:DS00180.3" CG16884 16-Dec-15 2015_12 ENSXETG00000000145() "visible,size defective" "wing vein L3,wing vein L4,anterior crossvein,ectopic,posterior crossvein,wing,posterior,wing cell" FBgn0060837 l(3)S049610 lethal (3) S049610 http://flybase.net/reports/FBgn0060837.html gene 0496/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0032669 CG15155 http://flybase.net/reports/FBgn0032669.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" CT35055 "IPR013653=FR47-like, IPR016181=Acyl-CoA N-acyltransferase" CG15155 16-Dec-15 2015_12 ENSDARG00000051954(LOC799646) viable FBgn0050402 CG30402 http://flybase.net/reports/FBgn0050402.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030310 PGRP-SA Peptidoglycan recognition protein SA http://flybase.net/reports/FBgn0030310.html "FBgn0061434, FBgn0064989" protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0032500=muramyl dipeptide binding, 0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0008329=signaling pattern recognition receptor activity, 0016019=peptidoglycan receptor activity" "0016045=detection of bacterium, 0008063=Toll signaling pathway, 0006965=positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria, 0032494=response to peptidoglycan, 0050830=defense response to Gram-positive bacterium, 0008592=regulation of Toll signaling pathway, 0006952=defense response, 0009253=peptidoglycan catabolic process, 0006955=immune response, 0045087=innate immune response" "0005576=extracellular region, 0005887=integral component of plasma membrane" "SA, BcDNA:AT30827, CG11709, peptidoglycan recognition protein SA, Peptidoglycan-recognition protein-SA precursor, Dm PGRP-SA, seml, semmelweiss, Peptidoglycan recognition protein-SA, Protein semmelweis, SEMMELWEIS, semmelweis, PG Recognition Protein-SA" "IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR017331=Peptidoglycan recognition protein, PGRP-S" CG11709 16-Dec-15 2015_12 "immune response defective,viable" FBgn0040398 CG14629 http://flybase.net/reports/FBgn0040398.html FBgn0029556 protein_coding_gene EG:103E12.2 IPR009832=Protein of unknown function DUF1397 CG14629 16-Dec-15 2015_12 FBgn0033041 Or42a Odorant receptor 42a http://flybase.net/reports/FBgn0033041.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0042048=olfactory behavior, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "41E.2, 42a, OR42a, DOR117, Or42A, CG17250" "IPR004117=Olfactory receptor, Drosophila" CG17250 16-Dec-15 2015_12 "smell perception defective,viable,fertile" adult olfactory receptor neuron Or42a FBgn0000306 che cherub http://flybase.net/reports/FBgn0000306.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,sterile,female sterile" wing FBgn0024631 l(2)k14316 lethal (2) k14316 http://flybase.net/reports/FBgn0024631.html gene 143/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0001278 J Jammed http://flybase.net/reports/FBgn0001278.html gene 16-Dec-15 2015_12 "visible,heat sensitive,viable,lethal,recessive,reduced" "wing,alula" FBgn0015584 Acp53Ea Accessory gland protein 53Ea http://flybase.net/reports/FBgn0015584.html FBgn0063350 protein_coding_gene 0005179=hormone activity "0046692=sperm competition, 0007321=sperm displacement, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "Acp53E, Accessory gland protein 53Ea, BcDNA:AT09943, CG8622, ACP53EA, Accessory gland-specific peptide 53Ea" IPR009392=Drosophila ACP53EA CG8622 16-Dec-15 2015_12 adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0042165 CG18845 http://flybase.net/reports/FBgn0042165.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065461 l(2)SH1372 lethal (2) SH1372 http://flybase.net/reports/FBgn0065461.html gene l(2)SH2 1372 16-Dec-15 2015_12 "lethal,recessive" FBgn0022257 l(2)k01006 lethal (2) k01006 http://flybase.net/reports/FBgn0022257.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039453 CG6403 http://flybase.net/reports/FBgn0039453.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG6403 16-Dec-15 2015_12 viable FBgn0037120 CG11247 http://flybase.net/reports/FBgn0037120.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0051726=regulation of cell cycle "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG11247 16-Dec-15 2015_12 YPR186C(PZF1) WBGene00016154(C27A12.2) "viable,fertile" DRSC26558 K -0.214621344 0.430984818 0.101049218 -0.17493128 0.429641584 -1.529961902 FBgn0039955 CG41099 http://flybase.net/reports/FBgn0039955.html "FBgn0039957, FBgn0042091, FBan0041099" protein_coding_gene 0046872=metal ion binding "0003382=epithelial cell morphogenesis, 0048598=embryonic morphogenesis, 0006897=endocytosis" 0005773=vacuole "GM10035, D-Rabankyrin, CG17419, BEST:GM10035, CG17416, Rabankyrin-5" "IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR000306=FYVE zinc finger, IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG41099 16-Dec-15 2015_12 ENSDARG00000061013(ankfy1) WBGene00009064(F22G12.4) ENSXETG00000025613() ENSMUSG00000020790(Ankfy1) ENSG00000185722(ANKFY1) viable FBgn0266736 CR45209 http://flybase.net/reports/FBgn0266736.html non_protein_coding_gene CR45209 16-Dec-15 2015_12 FBgn0262402 mir-311 mir-311 stem loop http://flybase.net/reports/FBgn0262402.html "FBgn0067693, FBgn0262236" miRNA_gene "0007391=dorsal closure, 0071732=cellular response to nitric oxide, 0008258=head involution" "311, Dme-miR-311, CR42943, mIR-310s, mIR-311, dme-mir-311, miR-311, mir-311, CR33615" CR42943 16-Dec-15 2015_12 "viable,visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,partially lethal - majority die" "wing,wing vein,1st posterior cell" FBgn0030786 mRpL22 mitochondrial ribosomal protein L22 http://flybase.net/reports/FBgn0030786.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005739=mitochondrion" "CG4742, L22, ribosomal protein L22" "IPR001063=Ribosomal protein L22/L17, IPR005727=Ribosomal protein L22, bacterial/chloroplast-type" CG4742 16-Dec-15 2015_12 ENSDARG00000060798(LOC100331430) WBGene00012645(Y39A1A.6) ENSXETG00000019403(MRPL22) ENSMUSG00000020514(Mrpl22) ENSG00000082515(MRPL22) "viable,visible" "trichogen cell,mesothoracic tergum" DRSC19915 K -0.906735727 -0.25072513 -0.178543384 -0.409460697 -1.94043949 -0.252965782 FBgn0069402 KH3 KH3 http://flybase.net/reports/FBgn0069402.html gene 0016063=rhodopsin biosynthetic process 16-Dec-15 2015_12 FBgn0001728 l(1)ESHS49 lethal (1) ESHS49 http://flybase.net/reports/FBgn0001728.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025814 Mgstl Microsomal glutathione S-transferase-like http://flybase.net/reports/FBgn0025814.html "FBgn0031147, FBgn0047002, FBgn0061409" protein_coding_gene 0004364=glutathione transferase activity "0005741=mitochondrial outer membrane, 0005811=lipid particle, 0043231=intracellular membrane-bounded organelle" "Mgst1, CG1742, microsomal glutathione, microsomal glutathione transferase 1, BcDNA:RH59553, BcDNA:RE10696, transferase" "IPR023352=Membrane associated eicosanoid/glutathione metabolism-like domain, IPR001129=Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein" CG1742 16-Dec-15 2015_12 "ENSDARG00000032618(mgst1),ENSDARG00000022165(zgc:92357)" ENSXETG00000014173(PTGES) ENSMUSG00000008540(Mgst1) ENSG00000008394(MGST1) "partially lethal - majority die,visible,viable,fertile,short lived" "eye,arista,tarsal segment,macrochaeta,wing,scutellum" FBgn0023083 fray frayed http://flybase.net/reports/FBgn0023083.html "FBgn0010922, FBgn0026023" protein_coding_gene "0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" "0007413=axonal fasciculation, 0008362=chitin-based embryonic cuticle biosynthetic process, 0072697=protein localization to cell cortex, 0035220=wing disc development, 0008366=axon ensheathment, 0006468=protein phosphorylation, 0046777=protein autophosphorylation, 0008065=establishment of blood-nerve barrier" 0005737=cytoplasm "Ste20-like protein kinase, Ste20-like, l(3)07551, Dosr1, STE20-like/SPAK, CG7693, dSTRAD, laggard, 4624, oxidative-stress-responsive kinase 1, lag, dOSR1, Fray" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR024678=Serine/threonine-protein kinase OSR1/WNK, CCT domain, IPR017441=Protein kinase, ATP binding site" CG7693 16-Dec-15 2015_12 "ENSDARG00000027500(oxsr1b),ENSDARG00000034189(oxsr1a)" WBGene00013355(gck-3) "ENSXETG00000014499(oxsr1),ENSXETG00000016206(STK39)" "ENSMUSG00000036737(Oxsr1),ENSMUSG00000027030(Stk39)" "ENSG00000172939(OXSR1),ENSG00000198648(STK39)" " embryonic stage | stage >=15 , embryonic stage | stage >=12 , embryonic stage | early , embryonic stage | stage 17 " " abdominal ventral oblique muscle 6

, larval hindgut

, exit glial cell

, larval midgut

, larval proventriculus

, dorsal neurohemal organ

" "visible,viable,fertile,lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "wing vein,ectopic,wing vein L4,embryonic/first instar larval cuticle,maternal effect,embryonic/larval peripheral nervous system,trichogen cell,posterior wing margin" DRSC16950 K 0.194590866 0.670186911 1.095502173 0.002877787 1.959282807 0.23182972 FBgn0063356 CR30370 http://flybase.net/reports/FBgn0063356.html FBgn0050370 non_protein_coding_gene BcDNA:AT05157 16-Dec-15 2015_12 FBgn0040692 CG13938 http://flybase.net/reports/FBgn0040692.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039912 CG11260 http://flybase.net/reports/FBgn0039912.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019784 l(1)218 lethal (1) 218 http://flybase.net/reports/FBgn0019784.html gene 16-Dec-15 2015_12 "lethal,partially,recessive" FBgn0038392 CG17631 http://flybase.net/reports/FBgn0038392.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0033899 CG13016 http://flybase.net/reports/FBgn0033899.html protein_coding_gene IPR019397=Uncharacterised protein family TMEM39 CG13016 16-Dec-15 2015_12 "ENSDARG00000018956(tmem39b),ENSDARG00000070643(zgc:65781)" WBGene00017003(D1007.5) "ENSXETG00000023015(Q6GL42_XENTR),ENSXETG00000005243(TMEM39B)" "ENSMUSG00000002845(Tmem39a),ENSMUSG00000053730(Tmem39b)" "ENSG00000176142(TMEM39A),ENSG00000121775(TMEM39B)" viable FBgn0001730 l(1)ESHS51 lethal (1) ESHS51 http://flybase.net/reports/FBgn0001730.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083960 CG34124 http://flybase.net/reports/FBgn0083960.html "FBan0031652, FBgn0051652" protein_coding_gene CG31652 "IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG34124 16-Dec-15 2015_12 ENSMUSG00000071550(Wdr52) "viable,fertile" FBgn0065472 l(2)SH1328 lethal (2) SH1328 http://flybase.net/reports/FBgn0065472.html gene l(2)SH2 1328 16-Dec-15 2015_12 "lethal,recessive" FBgn0031347 CG10869 http://flybase.net/reports/FBgn0031347.html protein_coding_gene CG10869 16-Dec-15 2015_12 viable FBgn0041007 CG17541 http://flybase.net/reports/FBgn0041007.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260350 GSd302 http://flybase.net/reports/FBgn0260350.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038722 Nup58 Nucleoporin 58kD http://flybase.net/reports/FBgn0038722.html protein_coding_gene 0005487=nucleocytoplasmic transporter activity "0006913=nucleocytoplasmic transport, 0048812=neuron projection morphogenesis" 0005643=nuclear pore "CG7360, Dm NUP58, Nucleoporin 58, RE52572p, Nup58" "IPR024945=Spt5 C-terminal domain, IPR024882=Nucleoporin p58/p45" CG7360 16-Dec-15 2015_12 ENSDARG00000033965(nupl1) ENSXETG00000010681(nupl1) ENSMUSG00000063895(Nupl1) ENSG00000139496(NUPL1) "sterile,partially lethal,viable" FBgn0037985 ssp5 short spindle 5 http://flybase.net/reports/FBgn0037985.html FBgn0044755 protein_coding_gene 0000022=mitotic spindle elongation "Tes59, anon-WO0140519.127, CG14735, Ssp5" CG14735 16-Dec-15 2015_12 viable FBgn0036490 CG6888 http://flybase.net/reports/FBgn0036490.html FBgn0065007 protein_coding_gene 0008379=thioredoxin peroxidase activity "0006974=cellular response to DNA damage stimulus, 0042744=hydrogen peroxide catabolic process, 0055114=oxidation-reduction process" "0070062=extracellular exosome, 0005737=cytoplasm" "6888, BcDNA:AT16346" "IPR012336=Thioredoxin-like fold, IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR019479=Peroxiredoxin, C-terminal, IPR024706=Peroxiredoxin, AhpC-type" CG6888 16-Dec-15 2015_12 "YML028W(TSA1),YDR453C(TSA2)" "viable,fertile" FBgn0005601 yemG2.8 yema gene 2.8 http://flybase.net/reports/FBgn0005601.html FBgn0004042 gene "yT2.8, yT2.6, yG2.8, yG2.8/2.6, unnamed, yG2.6" 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage | stage <=8 , embryonic stage | stage <6 , embryonic stage | stage <= 8 " " ovary

, organism

" FBgn0027560 Tps1 Trehalose-6-phosphate synthase 1 http://flybase.net/reports/FBgn0027560.html "FBgn0001908, FBgn0022028" protein_coding_gene "0003825=alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity" 0005992=trehalose biosynthetic process 0005811=lipid particle "lethal(2)24Ea, 19920676, BcDNA:GH08860, Trehalos-6-phosphate synthase, l(2)24Ea, trehalose-6-phosphate synthase, CG4104, CG4104 PA, TPS, l(2)jf5, l(2)jf4, TreS, trehalose-phosphate synthase, jf5, tps1, trehalose-6-phosphate synthase 1, dtps1, trehalose synthase, l(2)k08903" "IPR023214=HAD-like domain, IPR001830=Glycosyl transferase, family 20, IPR006379=HAD-superfamily hydrolase, subfamily IIB, IPR003337=Trehalose-phosphatase" CG4104 16-Dec-15 2015_12 YBR126C(TPS1) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "eye,ommatidium" FBgn0002995 om ommatidia http://flybase.net/reports/FBgn0002995.html gene 16-Dec-15 2015_12 "eye,ommatidium" FBgn0030799 CG4872 http://flybase.net/reports/FBgn0030799.html protein_coding_gene 0003714=transcription corepressor activity 0000122=negative regulation of transcription from RNA polymerase II promoter 0005737=cytoplasm "IPR016040=NAD(P)-binding domain, IPR003462=Ornithine cyclodeaminase/mu-crystallin, IPR023401=Ornithine cyclodeaminase, N-terminal" CG4872 16-Dec-15 2015_12 ENSDARG00000062817(zgc:158843) ENSXETG00000016698(CRYM) ENSMUSG00000030905(Crym) ENSG00000103316(CRYM) FBgn0015857 anon-14Aa anon-14Aa http://flybase.net/reports/FBgn0015857.html gene t6 16-Dec-15 2015_12 FBgn0005704 l(1)TK107 lethal (1) TK107 http://flybase.net/reports/FBgn0005704.html gene l107 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0019701 l(2)42Bb lethal (2) 42Bb http://flybase.net/reports/FBgn0019701.html gene "l(2)6G1, 6G1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0045473 Gr85a Gustatory receptor 85a http://flybase.net/reports/FBgn0045473.html FBgn0051405 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane CG31405 IPR013604=7TM chemoreceptor CG31405 16-Dec-15 2015_12 viable FBgn0267426 CR45779 http://flybase.net/reports/FBgn0267426.html pseudogene_attribute CR45779 16-Dec-15 2015_12 FBgn0010849 l(3)04837 lethal (3) 04837 http://flybase.net/reports/FBgn0010849.html gene 0035282=segmentation 16-Dec-15 2015_12 "lethal,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,maternal effect,segment" FBgn0031020 Nat1 NAT1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0031020.html FBgn0027223 protein_coding_gene 0004596=peptide alpha-N-acetyltransferase activity 0022008=neurogenesis 0072686=mitotic spindle "Nat1, dNat1, CG12202, l(1)G0311" "IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR021183=N-terminal acetyltransferase A, auxiliary subunit, IPR011990=Tetratricopeptide-like helical domain" CG12202 16-Dec-15 2015_12 "ENSDARG00000003213(naa15a),ENSDARG00000030368(naa15b)" YDL040C(NAT1) WBGene00021754(Y50D7A.4) "ENSXETG00000016900(NARG1),ENSXETG00000018897(NARG1L)" "ENSMUSG00000063273(Naa15),ENSMUSG00000022020(Naa16)" "ENSG00000164134(NAA15),ENSG00000172766(NAA16)" "viable,fertile,lethal,recessive,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC19440 IE 1.118109638 2.123228374 1.101715375 1.73970854 0.055528706 -0.511190298 FBgn0034617 CG9754 http://flybase.net/reports/FBgn0034617.html protein_coding_gene 0005634=nucleus CG9754 16-Dec-15 2015_12 "viable,female sterile" FBgn0046839 l(3)A4-4L1 lethal (3) A4-4L1 http://flybase.net/reports/FBgn0046839.html gene 16-Dec-15 2015_12 lethal FBgn0263845 CR43706 http://flybase.net/reports/FBgn0263845.html non_protein_coding_gene CR43706 16-Dec-15 2015_12 FBgn0265921 CR44710 http://flybase.net/reports/FBgn0265921.html non_protein_coding_gene lincRNA.1029 CR44710 16-Dec-15 2015_12 FBgn0262580 CG43120 http://flybase.net/reports/FBgn0262580.html protein_coding_gene "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG43120 16-Dec-15 2015_12 FBgn0000195 blc blocked http://flybase.net/reports/FBgn0000195.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile,male sterile" "germline cell,female" FBgn0000687 flrdJ flight reduced J http://flybase.net/reports/FBgn0000687.html gene 0007629=flight behavior flrdI 16-Dec-15 2015_12 flight defective FBgn0022935 D19A D19A http://flybase.net/reports/FBgn0022935.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "d19a, Zinc finger AT-hook protein, CG10269" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG10269 16-Dec-15 2015_12 YPR186C(PZF1) WBGene00004773(sem-4) viable DRSC11133 IEK -1.89875976 -2.851653906 -2.516288756 -4.184940303 0.494635396 1.650365893 FBgn0001048 fs(3)HO231 female sterile (3) HO231 http://flybase.net/reports/FBgn0001048.html gene fs(3)231A 16-Dec-15 2015_12 FBgn0033221 CG12825 http://flybase.net/reports/FBgn0033221.html protein_coding_gene dmCG12825 CG12825 16-Dec-15 2015_12 viable FBgn0262436 mir-310 mir-310 stem loop http://flybase.net/reports/FBgn0262436.html "FBgn0067694, FBgn0262288" miRNA_gene "0008258=head involution, 0071732=cellular response to nitric oxide, 0035282=segmentation, 0001745=compound eye morphogenesis" "mIR-310, miR310, Dme-miR-310, mir-310, Mir-310, miR-310, mIR-310s, CR42995, dme-mir-310, CR33614" CR42995 16-Dec-15 2015_12 "viable,visible,lethal - all die before end of larval stage,some die during larval stage,lethal,partially lethal - majority die" "wing hair,wing" FBgn0039505 CG5934 http://flybase.net/reports/FBgn0039505.html protein_coding_gene IPR019357=Predicted coiled-coil protein (DUF2205) CG5934 16-Dec-15 2015_12 "ENSDARG00000002217(zgc:101848),ENSDARG00000069712(LOC100329577)" ENSXETG00000016973(SCOC) ENSMUSG00000063253(Scoc) ENSG00000153130(SCOC) viable FBgn0030592 CG9514 http://flybase.net/reports/FBgn0030592.html protein_coding_gene "0008812=choline dehydrogenase activity, 0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity" "0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process" Dm GMCdelta1 "IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG9514 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) viable DRSC30059 K 0.878152916 0.267693627 0.167029725 0.592564886 0.343996625 -1.700268826 FBgn0036640 nxf2 nuclear RNA export factor 2 http://flybase.net/reports/FBgn0036640.html protein_coding_gene "0006406=mRNA export from nucleus, 0051028=mRNA transport" "0005737=cytoplasm, 0005654=nucleoplasm" "NXF2, CG4118" "IPR003603=U2A'/phosphoprotein 32 family A, C-terminal, IPR005637=TAP C-terminal (TAP-C) domain, IPR030217=Nuclear RNA export factor, IPR001611=Leucine-rich repeat, IPR018222=Nuclear transport factor 2, eukaryote, IPR009060=UBA-like" CG4118 16-Dec-15 2015_12 "female sterile,female fertile" DRSC10403 I -1.547157048 0.790849092 -0.046858054 0.276373273 -1.105280854 -0.112959855 FBgn0003479 spn-A spindle A http://flybase.net/reports/FBgn0003479.html FBgn0011700 protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0003697=single-stranded DNA binding, 0000150=recombinase activity, 0008094=DNA-dependent ATPase activity, 0003690=double-stranded DNA binding" "0007294=germarium-derived oocyte fate determination, 0030717=karyosome formation, 0006302=double-strand break repair, 0009951=polarity specification of dorsal/ventral axis, 0008298=intracellular mRNA localization, 0009994=oocyte differentiation, 0031000=response to caffeine, 0009949=polarity specification of anterior/posterior axis, 0006281=DNA repair, 0007143=female meiotic division, 0045003=double-strand break repair via synthesis-dependent strand annealing, 0010569=regulation of double-strand break repair via homologous recombination, 0048477=oogenesis, 0006310=DNA recombination, 1990426=homologous recombination-dependent replication fork processing" 0005634=nucleus "RAD51, DMR1, Dmrad51, rad51, DMR/DroRAD51, DMR, DmRad51, Rad51-like, RA51_DROME, spnA, D37788, Spindle-A, dmRAD51, SpnA, Rad51dm, spindle-A, dmrad51, RA51, Spn-A, CG7948, Rad51, Dm Rad51, DmRAD51" "IPR016467=DNA recombination and repair protein, RecA-like, IPR020587=DNA recombination and repair protein RecA, monomer-monomer interface, IPR011941=DNA recombination/repair protein Rad51, IPR013632=DNA recombination and repair protein Rad51, C-terminal, IPR010995=DNA repair Rad51/transcription factor NusA, alpha-helical, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003583=Helix-hairpin-helix DNA-binding motif, class 1, IPR020588=DNA recombination and repair protein RecA-like, ATP-binding domain, IPR003593=AAA+ ATPase domain" CG7948 16-Dec-15 2015_12 ENSDARG00000041411(rad51) YER095W(RAD51) WBGene00004297(rad-51) ENSXETG00000015951(RAD51) ENSMUSG00000027323(Rad51) ENSG00000051180(RAD51) "viable,lethal,maternal effect,semi-fertile,radiation sensitive,dominant,DNA repair defective,meiotic cell cycle defective,female,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,germline clone,chorion | dorsal | germline clone,egg,presumptive oocyte,karyosome,chorion,maternal effect,synaptonemal complexX3F),chorion | dorsalX3F),dorsal,oocyte,nurse cell,egg chamber,synaptonemal complex,germline cyst" DRSC16812 K -0.18460639 0.050961495 -0.157866144 0.030878465 2.326013271 0.759214734 FBgn0040905 CG15578 http://flybase.net/reports/FBgn0040905.html protein_coding_gene CG15578 16-Dec-15 2015_12 viable FBgn0010343 HIS-C Histone complex http://flybase.net/reports/FBgn0010343.html protein_coding_gene "histone, his, His-C" 16-Dec-15 2015_12 FBgn0024712 anon-57Co anon-57Co http://flybase.net/reports/FBgn0024712.html gene unnamed 16-Dec-15 2015_12 FBgn0060778 l(3)S060711a lethal (3) S060711a http://flybase.net/reports/FBgn0060778.html gene 0607/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0267478 CR45828 http://flybase.net/reports/FBgn0267478.html non_protein_coding_gene CR45828 16-Dec-15 2015_12 FBgn0038750 CG4465 http://flybase.net/reports/FBgn0038750.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG4465 16-Dec-15 2015_12 "viable,fertile" DRSC15584 E -0.01569009 -0.207640764 -1.832399723 -0.003269499 0.456789135 0.528808937 FBgn0046645 anon-38D.21 anon-38D.21 http://flybase.net/reports/FBgn0046645.html gene 38D.21 16-Dec-15 2015_12 FBgn0263898 A44 http://flybase.net/reports/FBgn0263898.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0065775 l(2)SH0454 lethal (2) SH0454 http://flybase.net/reports/FBgn0065775.html gene l(2)SH2 0454 16-Dec-15 2015_12 "lethal,recessive" FBgn0082954 snoRNA:ë¬28S-3571 snoRNA:ë¬28S-3571 http://flybase.net/reports/FBgn0082954.html snoRNA_gene "Psi 28S-3571, CR34611, chr3R:1423362..1423500, psi28s-3571" CR34611 16-Dec-15 2015_12 FBgn0053194 CheA29a Chemosensory protein A 29a http://flybase.net/reports/FBgn0053194.html FBgn0062414 protein_coding_gene "0043695=detection of pheromone, 0007606=sensory perception of chemical stimulus" 0005576=extracellular region "CG33194, CheA29a" CG33194 16-Dec-15 2015_12 adult stage | male " prothoracic tarsal segment

, prothoracic tarsal segment 3

, prothoracic tarsal segment 2

, head

, prothoracic tarsal segment 1

, prothoracic tarsal segment 4

" "viable,fertile" DRSC21486 K -0.328872632 0.196732457 0.688702037 0.631062025 -1.575566016 -1.801877171 FBgn0002308 l(3)84Ff lethal (3) 84Ff http://flybase.net/reports/FBgn0002308.html gene l(3)EfK3 16-Dec-15 2015_12 lethal FBgn0039333 CG11917 http://flybase.net/reports/FBgn0039333.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060604 l(3)S091104 lethal (3) S091104 http://flybase.net/reports/FBgn0060604.html gene 0911/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0065127 l(3)SH138 lethal (3) SH138 http://flybase.net/reports/FBgn0065127.html gene l(2)SH3 138 16-Dec-15 2015_12 "lethal,recessive" FBgn0001024 fs(3)A15 female sterile (3) A15 http://flybase.net/reports/FBgn0001024.html gene 16-Dec-15 2015_12 "female sterile,recessive,mitotic cell cycle defective" "female reproductive system,spindle" FBgn0265646 CR44453 http://flybase.net/reports/FBgn0265646.html non_protein_coding_gene lincRNA.293 CR44453 16-Dec-15 2015_12 FBgn0066084 RpL41 Ribosomal protein L41 http://flybase.net/reports/FBgn0066084.html "FBgn0046237, FBgn0047072, FBgn0050425, FBgn0063106" protein_coding_gene 0003735=structural constituent of ribosome "0002181=cytoplasmic translation, 0006412=translation" "0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus, 0022625=cytosolic large ribosomal subunit, 0005730=nucleolus, 0005654=nucleoplasm, 0000228=nuclear chromosome" "putative noncoding RNA 005:2R, L41, BcDNA:LP07070, CG30425, pncr005:2R, BcDNA:RE63504, BEST:LP07070, CR30425" IPR007836=Ribosomal protein L41 CG30425 16-Dec-15 2015_12 FBgn0040650 CG15456 http://flybase.net/reports/FBgn0040650.html protein_coding_gene 0008430=selenium binding 0045454=cell redox homeostasis "IPR012336=Thioredoxin-like fold, IPR011893=Selenoprotein, Rdx type" CG15456 16-Dec-15 2015_12 "ENSDARG00000038228,ENSDARG00000038227" ENSXETG00000015147(C17orf37) ENSMUSG00000002580(1810046J19Rik) ENSG00000141741(C17orf37) viable FBgn0266274 T:SS-trypsin Signal sequence of trypsin http://flybase.net/reports/FBgn0266274.html engineered_foreign_region 16-Dec-15 2015_12 FBgn0036440 CG17177 http://flybase.net/reports/FBgn0036440.html protein_coding_gene CG17177 16-Dec-15 2015_12 FBgn0060411 l(3)S130204b lethal (3) S130204b http://flybase.net/reports/FBgn0060411.html gene 1302/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003341 scrp scarp http://flybase.net/reports/FBgn0003341.html gene 16-Dec-15 2015_12 "eye,heat sensitive" FBgn0267182 CR45622 http://flybase.net/reports/FBgn0267182.html non_protein_coding_gene CR45622 16-Dec-15 2015_12 FBgn0015449 l(1)9Fi lethal (1) 9Fi http://flybase.net/reports/FBgn0015449.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0034422 CG7137 http://flybase.net/reports/FBgn0034422.html protein_coding_gene "0008168=methyltransferase activity, 0035064=methylated histone binding" 0000183=chromatin silencing at rDNA "0005730=nucleolus, 0005677=chromatin silencing complex, 0033553=rDNA heterochromatin" Gene 3 "IPR007823=Methyltransferase-related, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG7137 16-Dec-15 2015_12 ENSDARG00000071652(wu:fk33d07) YDR083W(RRP8) WBGene00020296(T07A9.8) ENSXETG00000021400(RRP8) ENSG00000132275(RRP8) "viable,visible" trichogen cell FBgn0037356 CG12170 http://flybase.net/reports/FBgn0037356.html FBgn0062064 protein_coding_gene 0004315=3-oxoacyl-[acyl-carrier-protein] synthase activity 0006633=fatty acid biosynthetic process anon-WO0118547.367 "IPR014031=Beta-ketoacyl synthase, C-terminal, IPR014030=Beta-ketoacyl synthase, N-terminal, IPR016039=Thiolase-like, IPR018201=Beta-ketoacyl synthase, active site, IPR017568=3-oxoacyl-[acyl-carrier-protein] synthase 2" CG12170 16-Dec-15 2015_12 ENSDARG00000063668 YER061C(CEM1) WBGene00008667(F10G8.9) ENSXETG00000019896(OXSM) ENSMUSG00000021786(Oxsm) ENSG00000151093(OXSM) viable FBgn0264898 CR44089 http://flybase.net/reports/FBgn0264898.html non_protein_coding_gene CR44089 16-Dec-15 2015_12 FBgn0033734 CG8520 http://flybase.net/reports/FBgn0033734.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" FBgn 33734 "IPR005654=ATPase, AFG1-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8520 16-Dec-15 2015_12 "ENSDARG00000011466,ENSDARG00000042902(lace1b)" YEL052W(AFG1) WBGene00016261(C30F12.2) ENSMUSG00000038302(Lace1) ENSG00000135537(LACE1) "viable,fertile" FBgn0053470 CG33470 http://flybase.net/reports/FBgn0053470.html protein_coding_gene unnamed CG33470 16-Dec-15 2015_12 FBgn0033861 CG12464 http://flybase.net/reports/FBgn0033861.html protein_coding_gene CG12464 16-Dec-15 2015_12 viable FBgn0025576 M285 M285 http://flybase.net/reports/FBgn0025576.html gene "0007423=sensory organ development, 0008587=imaginal disc-derived wing margin morphogenesis, 0007219=Notch signaling pathway, 0007399=nervous system development" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0084025 CG41464 http://flybase.net/reports/FBgn0084025.html FBan0041464 protein_coding_gene 16-Dec-15 2015_12 FBgn0044506 BS\RTase RTase http://flybase.net/reports/FBgn0044506.html transposable_element_gene "RT, Bs ORF2, RTase" 16-Dec-15 2015_12 FBgn0036838 CG3808 http://flybase.net/reports/FBgn0036838.html protein_coding_gene "0008173=RNA methyltransferase activity, 0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" 0006396=RNA processing cg3808 "IPR030391=RNA methyltransferase TrmA, conserved site, IPR030390=RNA methyltransferase TrmA, active site, IPR000504=RNA recognition motif domain, IPR010280=(Uracil-5)-methyltransferase family, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR012677=Nucleotide-binding alpha-beta plait domain" CG3808 16-Dec-15 2015_12 ENSDARG00000002830(trmt2a) YKR056W(TRM2) WBGene00019241(H24K24.4) ENSXETG00000006323(TRMT2A) ENSMUSG00000022721(Trmt2a) ENSG00000099899(TRMT2A) "viable,fertile" FBgn0058257 CR40257 http://flybase.net/reports/FBgn0058257.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0065817 l(2)SH0377 lethal (2) SH0377 http://flybase.net/reports/FBgn0065817.html gene l(2)SH2 0377 16-Dec-15 2015_12 "lethal,recessive" FBgn0052791 DIP-ë± Dpr-interacting protein ë± http://flybase.net/reports/FBgn0052791.html "FBgn0029668, FBgn0029670" protein_coding_gene "CG13019, 32791, CG32791, CG13020, DIP-alpha" "IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG32791 16-Dec-15 2015_12 WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" "visible,partially lethal - majority die,some die during pupal stage,lethal" "chaeta,supernumerary,trichogen cell" FBgn0060840 l(3)S049508b lethal (3) S049508b http://flybase.net/reports/FBgn0060840.html gene 0495/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0050371 CG30371 http://flybase.net/reports/FBgn0050371.html FBgn0033281 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG2280, SP80" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR000859=CUB domain" CG30371 16-Dec-15 2015_12 "ENSDARG00000060754(LOC557248),ENSDARG00000061173(st14a),ENSDARG00000062758" ENSXETG00000017920(BC076994.1) "ENSMUSG00000031995(St14),ENSMUSG00000016942(Tmprss6),ENSMUSG00000033177(Tmprss7)" "ENSG00000149418(ST14),ENSG00000187045(TMPRSS6),ENSG00000176040(TMPRSS7)" "viable,visible" "antenna,leg,ectopic" FBgn0025472 qkr58E-5 quaking related 58E-5 http://flybase.net/reports/FBgn0025472.html gene qrk58E-5 16-Dec-15 2015_12 FBgn0267739 CR46070 http://flybase.net/reports/FBgn0267739.html non_protein_coding_gene Mgn3671 CR46070 16-Dec-15 2015_12 FBgn0051754 His-ë¬:CR31754 His-ë¬:CR31754 http://flybase.net/reports/FBgn0051754.html pseudogene_attribute "His-Psi:CR31754, CR31754" CR31754 16-Dec-15 2015_12 DRSC22051 IE 1.765175641 -3.517577589 -1.389565049 -5.118172072 0.626504918 0.964516608 FBgn0263841 CG43702 http://flybase.net/reports/FBgn0263841.html protein_coding_gene CG43702 16-Dec-15 2015_12 FBgn0029895 CG14441 http://flybase.net/reports/FBgn0029895.html protein_coding_gene 0008270=zinc ion binding 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG14441 16-Dec-15 2015_12 "viable,fertile" FBgn0037005 CG5078 http://flybase.net/reports/FBgn0037005.html protein_coding_gene 0015144=carbohydrate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR001958=Tetracycline resistance protein, TetA/multidrug resistance protein MdtG, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG5078 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0000683 flrdF flight reduced F http://flybase.net/reports/FBgn0000683.html gene 0007629=flight behavior 16-Dec-15 2015_12 "jumping defective,flightless" FBgn0065115 l(3)SH160 lethal (3) SH160 http://flybase.net/reports/FBgn0065115.html gene l(2)SH3 160 16-Dec-15 2015_12 "lethal,recessive" FBgn0065493 l(2)SH1228 lethal (2) SH1228 http://flybase.net/reports/FBgn0065493.html gene l(2)SH2 1228 16-Dec-15 2015_12 "lethal,recessive" FBgn0267802 CR46127 http://flybase.net/reports/FBgn0267802.html non_protein_coding_gene CR46127 16-Dec-15 2015_12 FBgn0029789 CG3160 http://flybase.net/reports/FBgn0029789.html protein_coding_gene "0004518=nuclease activity, 0042578=phosphoric ester hydrolase activity" "0006886=intracellular protein transport, 0015798=myo-inositol transport, 0006505=GPI anchor metabolic process" 0005783=endoplasmic reticulum "IPR029058=Alpha/Beta hydrolase fold, IPR012908=GPI inositol-deacylase PGAP1-like" CG3160 16-Dec-15 2015_12 ENSDARG00000062465(pgap1) YFL025C(BST1) ENSMUSG00000070889(Pgap1) ENSG00000197121(PGAP1) "viable,body color defective" mesothoracic tergum FBgn0031187 Usp2 Ubiquitin specific protease 2 http://flybase.net/reports/FBgn0031187.html protein_coding_gene "0005515=protein binding, 0070628=proteasome binding, 0004843=ubiquitin-specific protease activity, 1990380=Lys48-specific deubiquitinase activity" "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0071108=protein K48-linked deubiquitination, 0045824=negative regulation of innate immune response, 1900425=negative regulation of defense response to bacterium, 1901800=positive regulation of proteasomal protein catabolic process, 0002785=negative regulation of antimicrobial peptide production" "Q9VR54, CG14619" "IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain" CG14619 16-Dec-15 2015_12 "YDR069C(DOA4),YER144C(UBP5)" ENSXETG00000017669(USP21) "lethal,recessive,body color defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable,locomotor behavior defective,short lived" "mesothoracic tergum,prepupa" FBgn0000365 cpw canopy wing http://flybase.net/reports/FBgn0000365.html gene 16-Dec-15 2015_12 "male sterile,partially lethal - majority die,visible,recessive,viable,male,reduced" "wing,wing vein,eye,ocellar bristle,thorax,adult thorax,macrochaeta,microchaeta,head bristle" FBgn0031268 cold coiled http://flybase.net/reports/FBgn0031268.html protein_coding_gene "0060856=establishment of blood-brain barrier, 0035151=regulation of tube size, open tracheal system, 0019991=septate junction assembly, 0042060=wound healing, 0035633=maintenance of blood-brain barrier" 0005737=cytoplasm "coiled, CG2813, cg2813, leaky4, cold" CG2813 16-Dec-15 2015_12 "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval dorsal trunk,presumptive embryonic/larval tracheal system,subperineurial glial cell,trichogen cell" FBgn0000333 cmd carminoid http://flybase.net/reports/FBgn0000333.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0025870 C141 C141 http://flybase.net/reports/FBgn0025870.html gene 0007628=adult walking behavior 16-Dec-15 2015_12 FBgn0069929 CG41122 http://flybase.net/reports/FBgn0069929.html FBan0041122 protein_coding_gene 16-Dec-15 2015_12 FBgn0014932 anon-87Ea anon-87Ea http://flybase.net/reports/FBgn0014932.html gene "A transcript, A, Transcription unit A" 16-Dec-15 2015_12 FBgn0003139 PpV Protein phosphatase V http://flybase.net/reports/FBgn0003139.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0016787=hydrolase activity" "0000278=mitotic cell cycle, 0000082=G1/S transition of mitotic cell cycle, 0006470=protein dephosphorylation" 0005737=cytoplasm "DmPpV-6A, PPV 6A, protein phosphatase V, PP6, dPP6, PpV[[C]], Ppv, PPV, CG12217, PPPV6A" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase" CG12217 16-Dec-15 2015_12 ENSDARG00000002949(ppp6c) ENSXETG00000016831(PPP6C) ENSMUSG00000026753(Ppp6c) ENSG00000119414(PPP6C) " embryonic stage | stage 5 , embryonic stage -- adult stage , embryonic stage | stage 4 " organism

" embryonic stage | stage 4 , embryonic stage | stage 5 " organism

"visible,viable" "wing,trichogen cell" FBgn0267727 Pen Pendulin http://flybase.net/reports/FBgn0267727.html "FBgn0011823, FBgn0014274, FBgn0026803, FBgn0044610, FBgn0022138" protein_coding_gene "0008320=protein transmembrane transporter activity, 0008565=protein transporter activity" "0048542=lymph gland development, 0016482=cytoplasmic transport, 0008283=cell proliferation, 0007303=cytoplasmic transport, nurse cell to oocyte, 0006607=NLS-bearing protein import into nucleus, 0000059=protein import into nucleus, docking, 0051298=centrosome duplication, 0042332=gravitaxis, 0007291=sperm individualization, 0007301=female germline ring canal formation, 0006606=protein import into nucleus" "0005643=nuclear pore, 0005875=microtubule associated complex, 0005811=lipid particle, 0005634=nucleus, 0005737=cytoplasm, 0015629=actin cytoskeleton" "Dalpha2, importin-alpha2, Importin-alpha, pendulin, Imp-alpha2, Importin alpha2, Rch1, pen-2, importin alpha2/pendulin, impalpha2, importin alpha2, Kap-alpha2, CG4799, oho-31, anon-WO0140519.258, 2.1, Kpna2, Importin-alpha2, alpha-importin, alpha2, alpha2A-Kap, l(2)k14401, lethal (2) k06324, oho31, IMPalpha2, Importin alpha, Importin-a2, imp alpha2, OHO31, l(2)k06324, bs29g06.y1, Kap alpha2, alphaKap2, PENdulin, pen, i, l(2)144/1, DPend, imp-alpha2, Dimp-alpha2, Oho31" "IPR011989=Armadillo-like helical, IPR002652=Importin-alpha, importin-beta-binding domain, IPR016024=Armadillo-type fold, IPR000225=Armadillo, IPR024931=Importin subunit alpha" CG4799 16-Dec-15 2015_12 "ENSDARG00000038066(kpna2),ENSDARG00000027169(zgc:55877)" "ENSXETG00000001594(kpna2),ENSXETG00000007497(KPNA7)" ENSMUSG00000018362(Kpna2) "ENSG00000215769,ENSG00000182481(KPNA2),ENSG00000185467(KPNA7)" " embryonic stage | early , adult stage , embryonic stage | stage >12 , larval stage | third instar , embryonic stage | gastrula , embryonic stage | embryonic cycle 10-13 , embryonic stage | extended germ band , embryonic stage | 0-2 hr , embryonic stage -- adult stage " " ventral nerve cord

, lymph gland

,organism | segmentally repeated , larval brain | restricted

, embryonic brain | restricted

, pole cell

, ventral nerve cord primordium

, imaginal disc

,

ubiquitous , neuroblast

, ring gland

" " embryonic stage -- adult stage , embryonic stage && larval stage && adult stage " FBgn0044102 E(rst)C463 E(rst)C463 http://flybase.net/reports/FBgn0044102.html gene 0001745=compound eye morphogenesis C463 16-Dec-15 2015_12 viable FBgn0044500 DTD44.3 DTD44.3 http://flybase.net/reports/FBgn0044500.html gene 16-Dec-15 2015_12 viable FBgn0265078 CR44189 http://flybase.net/reports/FBgn0265078.html non_protein_coding_gene lincRNA.197 CR44189 16-Dec-15 2015_12 FBgn0264523 ff14 http://flybase.net/reports/FBgn0264523.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" spermatid FBgn0061507 l(2)24Ac lethal (2) 24Ac http://flybase.net/reports/FBgn0061507.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060348 l(3)S142814b lethal (3) S142814b http://flybase.net/reports/FBgn0060348.html gene 1428/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0262549 Mod(GMroX1)B http://flybase.net/reports/FBgn0262549.html gene Complementation group B 16-Dec-15 2015_12 "lethal,female,recessive,male" FBgn0027196 l(2)32e lethal (2) 32e http://flybase.net/reports/FBgn0027196.html gene l[32e] 16-Dec-15 2015_12 "lethal,recessive" FBgn0032216 Usp14 Ubiquitin specific protease 14 http://flybase.net/reports/FBgn0032216.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0016567=protein ubiquitination, 0016579=protein deubiquitination, 0006511=ubiquitin-dependent protein catabolic process" 0005875=microtubule associated complex "Ubp6p, DmUsp14, Q9VKZ8, CG5384" "IPR029071=Ubiquitin-related domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR000626=Ubiquitin domain, IPR018200=Ubiquitin specific protease, conserved site, IPR028889=Ubiquitin specific protease domain" CG5384 16-Dec-15 2015_12 ENSDARG00000025889(usp14) YFR010W(UBP6) WBGene00006856(usp-14) ENSXETG00000003152(usp14) ENSMUSG00000047879(Usp14) ENSG00000101557(USP14) "viable,fertile,locomotor behavior defective,short lived" FBgn0051228 tRNA:CR31228 transfer RNA:CR31228 http://flybase.net/reports/FBgn0051228.html FBgn0060111 tRNA_gene 0033423=CCA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3R.trna48-ProTGG, AE002708.trna42-ProTGG, tRNA:P:TGG:AE002708-d, CR31228" CR31228 16-Dec-15 2015_12 FBgn0022096 l(2)k07215 lethal (2) k07215 http://flybase.net/reports/FBgn0022096.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260253 GSd334 http://flybase.net/reports/FBgn0260253.html gene 16-Dec-15 2015_12 lethal FBgn0037039 CG10587 http://flybase.net/reports/FBgn0037039.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space SP167 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG10587 16-Dec-15 2015_12 "viable,fertile" FBgn0040671 CG12569 http://flybase.net/reports/FBgn0040671.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038565 CG7794 http://flybase.net/reports/FBgn0038565.html FBgn0044684 protein_coding_gene "0003924=GTPase activity, 0005200=structural constituent of cytoskeleton, 0005525=GTP binding" "0007017=microtubule-based process, 0051258=protein polymerization" 0005874=microtubule "anon-WO0140519.191, unnamed" "IPR002452=Alpha tubulin, IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR000217=Tubulin, IPR008280=Tubulin/FtsZ, C-terminal" CG7794 16-Dec-15 2015_12 viable FBgn0065602 l(2)SH0865 lethal (2) SH0865 http://flybase.net/reports/FBgn0065602.html gene l(2)SH2 0865 16-Dec-15 2015_12 "lethal,recessive" FBgn0000959 fs(2)E6 female sterile (2) E6 http://flybase.net/reports/FBgn0000959.html gene fs2.6 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0262464 mir-6-1 mir-6-1 stem loop http://flybase.net/reports/FBgn0262464.html "FBgn0046819, FBgn0262340" miRNA_gene 0060548=negative regulation of cell death "dme-mir-6-1, miR-6, mir-6, Dme-miR-6, 6-1, CR33004, miR6-1, CR43047, mir-6-1, miR-6-1" CR43047 16-Dec-15 2015_12 " embryonic stage , larval stage | first instar " visible chaeta FBgn0267250 l(3)j13C8 http://flybase.net/reports/FBgn0267250.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086448 Gpi1 Gpi1 http://flybase.net/reports/FBgn0086448.html "FBgn0042713, FBgn0001537, FBgn0052578, FBgn0063603" protein_coding_gene 0017176=phosphatidylinositol N-acetylglucosaminyltransferase activity 0006506=GPI anchor biosynthetic process "0005789=endoplasmic reticulum membrane, 0016021=integral component of membrane" "CG32578, l(1)i19e, l(1)i19, dGpi1, lethal (1) 14Ca, l(1)14Cd, l(1)19-134, Dm_CAC10056/216-441, i19e, l(1)14Ca" IPR007720=N-acetylglucosaminyl transferase component CG32578 16-Dec-15 2015_12 WBGene00008504(F01G4.5) FBgn0008639 66Dem 66Dem http://flybase.net/reports/FBgn0008639.html gene 16-Dec-15 2015_12 FBgn0266466 cashew http://flybase.net/reports/FBgn0266466.html gene 16-Dec-15 2015_12 "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0046846 dec-1::Dvir\dec-1 1-Dec http://flybase.net/reports/FBgn0046846.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0004794 war warbler http://flybase.net/reports/FBgn0004794.html gene 0007300=ovarian nurse cell to oocyte transport 16-Dec-15 2015_12 female sterile FBgn0030137 CG15317 http://flybase.net/reports/FBgn0030137.html protein_coding_gene CG15317 16-Dec-15 2015_12 FBgn0000280 Cec-ë¬1 Cecropin pseudogene 1 http://flybase.net/reports/FBgn0000280.html pseudogene_attribute "unnamed, CecPsi1, CR32926, Crecopin A2 Psi, cec-Psi1, cecropin Psi-1, pseudo-1" CR32926 16-Dec-15 2015_12 FBgn0015985 l(2)PC4-N lethal (2) PC4-N http://flybase.net/reports/FBgn0015985.html gene fs(2)PC4-N 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0085318 CG34289 http://flybase.net/reports/FBgn0085318.html protein_coding_gene 0008270=zinc ion binding "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG34289 16-Dec-15 2015_12 FBgn0000749 fs(1)A336 female sterile (1) A336 http://flybase.net/reports/FBgn0000749.html gene fs(1)336 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0051956 pgant4 polypeptide GalNAc transferase 4 http://flybase.net/reports/FBgn0051956.html "FBgn0031541, FBgn0063613" protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity "0051047=positive regulation of secretion, 0006493=protein O-linked glycosylation, 0033363=secretory granule organization" "CG8845b, CG8845, CG31956" "IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain, IPR029044=Nucleotide-diphospho-sugar transferases" CG31956 16-Dec-15 2015_12 ENSDARG00000042778(galnt10) WBGene00001635(gly-10) "ENSXETG00000008481(GALNT10),ENSXETG00000016922(GALNTL6)" ENSMUSG00000020520(Galnt10) "ENSG00000164574(GALNT10),ENSG00000174473(GALNTL6)" "lethal,viable" "embryonic/larval proventriculus outer layer,secretory granuleunspecified,secretory granuletim-02)" FBgn0030905 CG15059 http://flybase.net/reports/FBgn0030905.html protein_coding_gene CG15059 16-Dec-15 2015_12 viable FBgn0262410 mir-6-2 mir-6-2 stem loop http://flybase.net/reports/FBgn0262410.html "FBgn0046818, FBgn0262247" miRNA_gene 0060548=negative regulation of cell death "mir-6-2, Dme-miR-6, 6-2, miR6-2, mir-6, miR-6, CR33040, dme-mir-6-2, CR42954, miR-6-2" CR42954 16-Dec-15 2015_12 " embryonic stage , larval stage | first instar " "visible,lethal" wing FBgn0011632 l(2)T57h10 lethal (2) T57h10 http://flybase.net/reports/FBgn0011632.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0000309 chl chaetelle http://flybase.net/reports/FBgn0000309.html gene 16-Dec-15 2015_12 "visible,recessive,female sterile" "macrochaeta,wing vein,genitalia,adult abdomen" FBgn0039459 IntS12 Integrator 12 http://flybase.net/reports/FBgn0039459.html protein_coding_gene 0008270=zinc ion binding "0034472=snRNA 3'-end processing, 0016180=snRNA processing, 0022008=neurogenesis" 0032039=integrator complex "CG5491, Int12, Integrator 12" "IPR001965=Zinc finger, PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR019787=Zinc finger, PHD-finger" CG5491 16-Dec-15 2015_12 ENSDARG00000009380(LOC100334713) ENSXETG00000014107(INTS12) ENSMUSG00000028016(Ints12) ENSG00000138785(INTS12) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000062 alb alberich http://flybase.net/reports/FBgn0000062.html gene 0007350=blastoderm segmentation 16-Dec-15 2015_12 "lethal,maternal effect" "embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11" FBgn0266502 s-256 http://flybase.net/reports/FBgn0266502.html gene 16-Dec-15 2015_12 FBgn0259544 B2009 http://flybase.net/reports/FBgn0259544.html gene 16-Dec-15 2015_12 FBgn0266906 CR45366 http://flybase.net/reports/FBgn0266906.html non_protein_coding_gene CR45366 16-Dec-15 2015_12 FBgn0038384 CG5470 http://flybase.net/reports/FBgn0038384.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267973 Ncoa6::sd http://flybase.net/reports/FBgn0267973.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0084094 E-3c1 Enhancer on chromosome 3-complementation group c1 http://flybase.net/reports/FBgn0084094.html gene E-3c 16-Dec-15 2015_12 "lethal,recessive" FBgn0082581 twiggy twiggy http://flybase.net/reports/FBgn0082581.html gene 0006909=phagocytosis 16-Dec-15 2015_12 FBgn0065161 l(3)SH043 lethal (3) SH043 http://flybase.net/reports/FBgn0065161.html gene l(2)SH3 043 16-Dec-15 2015_12 "lethal,recessive" FBgn0060661 l(3)S082414a lethal (3) S082414a http://flybase.net/reports/FBgn0060661.html gene 0824/14 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0016810 l(1)L11 lethal (1) L11 http://flybase.net/reports/FBgn0016810.html gene L11 16-Dec-15 2015_12 "lethal,recessive" FBgn0001339 l(1)1Bg lethal (1) 1Bg http://flybase.net/reports/FBgn0001339.html gene l(1)Bg 16-Dec-15 2015_12 lethal FBgn0051065 ppk31 pickpocket 31 http://flybase.net/reports/FBgn0051065.html protein_coding_gene "0005272=sodium channel activity, 0051536=iron-sulfur cluster binding" 0006814=sodium ion transport 0016021=integral component of membrane "pickpocket 31, CG31065, ppk31" "IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR001873=Na+ channel, amiloride-sensitive" CG31065 16-Dec-15 2015_12 "viable,lethal" DRSC13811 I 1.689848384 0.073480041 1.317502813 0.452099998 -0.243868111 0.013649685 FBgn0039799 CG15543 http://flybase.net/reports/FBgn0039799.html protein_coding_gene "0019205=nucleobase-containing compound kinase activity, 0005524=ATP binding" 0006139=nucleobase-containing compound metabolic process "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000850=Adenylate kinase/UMP-CMP kinase" CG15543 16-Dec-15 2015_12 viable FBgn0069446 E(br)420 E(br)420 http://flybase.net/reports/FBgn0069446.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029139 P(3)98DF P(3)98DF http://flybase.net/reports/FBgn0029139.html gene 16-Dec-15 2015_12 FBgn0267137 CR45577 http://flybase.net/reports/FBgn0267137.html non_protein_coding_gene CR45577 16-Dec-15 2015_12 FBgn0060984 l(3)S028218b lethal (3) S028218b http://flybase.net/reports/FBgn0060984.html gene 0282/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0040246 anon-57Bb anon-57Bb http://flybase.net/reports/FBgn0040246.html gene 16-Dec-15 2015_12 FBgn0030307 CG33235 http://flybase.net/reports/FBgn0030307.html FBgn0053235 protein_coding_gene CG15192 CG33235 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" FBgn0015425 l(1)1CDb lethal (1) 1CDb http://flybase.net/reports/FBgn0015425.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001879 l(1)YD23b lethal (1) YD23b http://flybase.net/reports/FBgn0001879.html gene l(1)YD23 16-Dec-15 2015_12 lethal FBgn0016053 pgc polar granule component http://flybase.net/reports/FBgn0016053.html FBgn0034719 protein_coding_gene "0007280=pole cell migration, 0007277=pole cell development, 0007281=germ cell development, 0045892=negative regulation of transcription, DNA-templated, 0008354=germ cell migration" "0045495=pole plasm, 0043186=P granule" "CR32885, pgc-1, unnamed, Polar granule component, Pgc, CG32885, 58D gene, Pgc1, pgr, CG11296" CG32885 16-Dec-15 2015_12 "viable,body color defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "mesothoracic tergum,pole cell,gonad" DRSC04099 E -1.48869092 0.286435893 3.129323254 0.228627332 0.121689279 -0.579230664 FBgn0265001 ppk18 pickpocket 18 http://flybase.net/reports/FBgn0265001.html "FBgn0032145, FBgn0032142" protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "pickpocket 18, CG13120, CG13121, CG44152, ppk18" "IPR001873=Na+ channel, amiloride-sensitive" CG44152 16-Dec-15 2015_12 FBgn0058445 CG40445 http://flybase.net/reports/FBgn0058445.html FBan0040445 protein_coding_gene 16-Dec-15 2015_12 FBgn0031125 CG11692 http://flybase.net/reports/FBgn0031125.html protein_coding_gene 16-Dec-15 2015_12 DRSC20484 K 0.849424643 -0.142604461 0.044316624 0.13591258 -0.469378822 -1.725126463 FBgn0267499 5.8SrRNA:CR45839 5.8S ribosomal RNA:CR45839 http://flybase.net/reports/FBgn0267499.html rRNA_gene CR45839 CR45839 16-Dec-15 2015_12 FBgn0052576 CG32576 http://flybase.net/reports/FBgn0052576.html "FBgn0043544, FBgn0045434, FBgn0047127" protein_coding_gene 0016192=vesicle-mediated transport "unnamed, anon-AE003501.1, NEST:bs01h05, BcDNA:RE29988" "IPR007305=Vesicle transport protein, Got1/SFT2-like" CG32576 16-Dec-15 2015_12 "ENSDARG00000071081,ENSDARG00000059308(golt1b),ENSDARG00000071077,ENSDARG00000022795(LOC567778)" YMR292W(GOT1) WBGene00018270(F41C3.4) ENSXETG00000008383(Q5RJU5_XENTR) ENSMUSG00000030245(Golt1b) ENSG00000111711(GOLT1B) DRSC19136 K 0.084884855 0.342205001 0.130742592 -0.608990982 0.120520048 1.589680424 FBgn0033104 CG15237 http://flybase.net/reports/FBgn0033104.html protein_coding_gene 0090266=regulation of mitotic cell cycle spindle assembly checkpoint 0005680=anaphase-promoting complex IPR026182=Anaphase-promoting complex subunit 15 CG15237 16-Dec-15 2015_12 viable FBgn0040630 CG12710 http://flybase.net/reports/FBgn0040630.html protein_coding_gene 16-Dec-15 2015_12 FBgn0021790 l(2)rAO135 lethal (2) rAO135 http://flybase.net/reports/FBgn0021790.html gene l(2)rA135 16-Dec-15 2015_12 "lethal,recessive" FBgn0052029 Cpr66D Cuticular protein 66D http://flybase.net/reports/FBgn0052029.html "FBgn0035919, FBgn0035920" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG6458, CG6469, DmelCpr66D, CG32029" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG32029 16-Dec-15 2015_12 "viable,fertile" FBgn0040336 Seipin Seipin http://flybase.net/reports/FBgn0040336.html FBgn0029631 protein_coding_gene "0032469=endoplasmic reticulum calcium ion homeostasis, 0046473=phosphatidic acid metabolic process, 0042594=response to starvation, 0010883=regulation of lipid storage, 0010884=positive regulation of lipid storage, 0006635=fatty acid beta-oxidation, 0090207=regulation of triglyceride metabolic process, 0046890=regulation of lipid biosynthetic process, 0008610=lipid biosynthetic process, 0046339=diacylglycerol metabolic process" 0005783=endoplasmic reticulum "CG9904, EG:BACR7C10.1, dSeipin" "IPR009617=Adipose-regulatory protein, Seipin" CG9904 16-Dec-15 2015_12 "ENSDARG00000037008(bscl2),ENSDARG00000025912(zgc:110829)" ENSXETG00000006021(BSCL2) ENSMUSG00000071657(Bscl2) ENSG00000168000(BSCL2) "decreased cell size,somatic clone,viable,fertile,lethal,nutrition conditional" "adult fat body,somatic clone,lipid particle | somatic clone,embryonic/larval fat body,nutrition conditional,fat body,salivary gland,lipid particle | ectopic,lipid particle,lipid particle | ectopicppl.PP,lipid particleppl.PP,lipid particle | ectopicelav.PU,lipid particle | ectopic48Y" FBgn0019731 l(1)A17 lethal (1) A17 http://flybase.net/reports/FBgn0019731.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028086 l(3)S084805 lethal (3) S084805 http://flybase.net/reports/FBgn0028086.html gene 0848/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0004031 wy wavy http://flybase.net/reports/FBgn0004031.html gene 16-Dec-15 2015_12 "visible,viable,fertile,lethal,male" "wing,abdomen,wing vein L1" FBgn0066330 rafl rafael http://flybase.net/reports/FBgn0066330.html gene "0048149=behavioral response to ethanol, 0007632=visual behavior, 0008542=visual learning, 0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 "memory defective,visual behavior defective,recessive,learning defective,neurophysiology defective,chemical sensitive" FBgn0050042 Cpr49Ab Cuticular protein 49Ab http://flybase.net/reports/FBgn0050042.html FBgn0033722 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG8496, DmelCpr49Ab, CG30042" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG30042 16-Dec-15 2015_12 viable FBgn0040132 l(2)22Ag lethal (2) 22Ag http://flybase.net/reports/FBgn0040132.html gene A 16-Dec-15 2015_12 "lethal,recessive" FBgn0038535 alt aluminum tubes http://flybase.net/reports/FBgn0038535.html protein_coding_gene "0012505=endomembrane system, 0005811=lipid particle" "Q9VEH0_DROME, CG18212" CG18212 16-Dec-15 2015_12 "ENSMUSG00000027422(Rrbp1),ENSMUSG00000021843(Ktn1)" "viable,fertile" FBgn0261850 Xpd Xeroderma pigmentosum D ortholog (H. sapiens) http://flybase.net/reports/FBgn0261850.html "FBgn0015844, FBgn0065247" protein_coding_gene "0005524=ATP binding, 0043141=ATP-dependent 5'-3' DNA helicase activity, 0000990=core RNA polymerase binding transcription factor activity, 0004386=helicase activity, 0003677=DNA binding" "0010972=negative regulation of G2/M transition of mitotic cell cycle, 0006367=transcription initiation from RNA polymerase II promoter, 0007088=regulation of mitotic nuclear division, 0006366=transcription from RNA polymerase II promoter, 0006974=cellular response to DNA damage stimulus, 0009411=response to UV, 0001113=transcriptional open complex formation at RNA polymerase II promoter, 0006289=nucleotide-excision repair, 0051983=regulation of chromosome segregation, 0007348=regulation of syncytial blastoderm mitotic cell cycle, 0001111=promoter clearance from RNA polymerase II promoter" "0005675=holo TFIIH complex, 0005705=polytene chromosome interband, 0005703=polytene chromosome puff, 0000439=core TFIIH complex, 0005700=polytene chromosome, 0005737=cytoplasm, 0005634=nucleus" "CG9433, XPD/ERCC2, xpd, lethal (2) SH2137, DhXPD, DmXPD, ERCC2, XPD, Xeroderma pigmentosum D, l(2)SH2 2137, l(2)SH2137, DhR3" "IPR014013=Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006555=ATP-dependent helicase, C-terminal, IPR006554=Helicase-like, DEXD box c2 type, IPR010643=Helical and beta-bridge domain, IPR001945=Xeroderma pigmentosum group D protein, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR013020=DNA helicase (DNA repair), Rad3 type, IPR010614=DEAD2" CG9433 16-Dec-15 2015_12 ENSDARG00000021985(ercc2) YER171W(RAD3) WBGene00021752(Y50D7A.2) ENSXETG00000018229(ERCC2) ENSMUSG00000030400(Ercc2) ENSG00000104884(ERCC2) " embryonic stage | syncytial blastoderm , larval stage | third instar , embryonic stage | stage 5 , embryonic stage | stage >5 " "

ubiquitous , larval salivary gland

,

, embryonic/larval fat body

" FBgn0003188 qui quit http://flybase.net/reports/FBgn0003188.html gene "0007297=ovarian follicle cell migration, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile "nurse follicle cell,ovary" FBgn0017420 su(RpII215)S3 su(RpII215)S3 http://flybase.net/reports/FBgn0017420.html gene "S3, anon-S3/S13, unnamed" 16-Dec-15 2015_12 FBgn0038248 CG7886 http://flybase.net/reports/FBgn0038248.html FBgn0044673 protein_coding_gene 0005813=centrosome anon-WO0140519.200 IPR026212=Centrosomal protein of 78kDa CG7886 16-Dec-15 2015_12 "ENSXETG00000014820(LRRC16A),ENSXETG00000022577(LRRC16B)" viable FBgn0013570 l(3)78Da lethal (3) 78Da http://flybase.net/reports/FBgn0013570.html gene 16-Dec-15 2015_12 lethal FBgn0084254 E-3c4 Enhancer on chromosome 3-complementation group c4 http://flybase.net/reports/FBgn0084254.html gene E-3c 16-Dec-15 2015_12 "lethal,recessive" FBgn0065259 l(2)SH2089 lethal (2) SH2089 http://flybase.net/reports/FBgn0065259.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262107 CR42860 http://flybase.net/reports/FBgn0262107.html non_protein_coding_gene CR42860 16-Dec-15 2015_12 FBgn0001598 l(1)CP8 lethal (1) CP8 http://flybase.net/reports/FBgn0001598.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021843 l(2)k14816 lethal (2) k14816 http://flybase.net/reports/FBgn0021843.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035799 CG14838 http://flybase.net/reports/FBgn0035799.html protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG14838 16-Dec-15 2015_12 ENSDARG00000009365 ENSXETG00000008630(WDR63) ENSMUSG00000043020(Wdr63) ENSG00000162643(WDR63) "viable,fertile" FBgn0085398 ppk9 pickpocket 9 http://flybase.net/reports/FBgn0085398.html "FBgn0034672, FBgn0034673" protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "ppk9, CG34369, CG13489, pickpocket 9, CG13490" "IPR001873=Na+ channel, amiloride-sensitive" CG34369 16-Dec-15 2015_12 DRSC04135 I 1.539440532 -1.736385215 -0.663016632 -1.327574442 -0.028808552 -0.56408249 FBgn0085252 CG34223 http://flybase.net/reports/FBgn0085252.html protein_coding_gene CG34223 16-Dec-15 2015_12 FBgn0034514 CG13427 http://flybase.net/reports/FBgn0034514.html protein_coding_gene 0007369=gastrulation 0031982=vesicle CG13427 16-Dec-15 2015_12 FBgn0070024 BG00488 BG00488 http://flybase.net/reports/FBgn0070024.html gene 16-Dec-15 2015_12 stress response defective FBgn0050201 tRNA:CR30201 transfer RNA:CR30201 http://flybase.net/reports/FBgn0050201.html FBgn0060052 tRNA_gene 0033407=UCA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:S:TGA:AE002575-b, CR30201, AE002575.trna9-SerTGA, chr2R.trna53-SerTGA, chr2R:18579596..18579746, tRNA[[Ser]]" CR30201 16-Dec-15 2015_12 FBgn0023110 anon-10Ax anon-10Ax http://flybase.net/reports/FBgn0023110.html gene 17 16-Dec-15 2015_12 FBgn0043849 412\ORF1 ORF1 http://flybase.net/reports/FBgn0043849.html transposable_element_gene ORF1 16-Dec-15 2015_12 FBgn0031048 CG12237 http://flybase.net/reports/FBgn0031048.html protein_coding_gene "0016462=pyrophosphatase activity, 0016791=phosphatase activity" 0008152=metabolic process 16769716 "IPR006383=HAD-superfamily hydrolase, subfamily IB, PSPase-like, IPR023214=HAD-like domain, IPR016965=Phosphatase PHOSPHO-type, IPR006384=Pyridoxal phosphate phosphatase-related" CG12237 16-Dec-15 2015_12 ENSDARG00000008403(phospho1) "ENSXETG00000018895(phospho2),ENSXETG00000018643(PHOSPHO1)" "ENSMUSG00000027088(Phospho2),ENSMUSG00000050860(Phospho1)" "ENSG00000144362(PHOSPHO2),ENSG00000173868(PHOSPHO1)" FBgn0029730 CG12681 http://flybase.net/reports/FBgn0029730.html protein_coding_gene CG12681 16-Dec-15 2015_12 viable FBgn0028945 CG7631 http://flybase.net/reports/FBgn0028945.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0006508=proteolysis, 0046331=lateral inhibition" BG:BACR44L22.6 "IPR024079=Metallopeptidase, catalytic domain, IPR006026=Peptidase, metallopeptidase, IPR001506=Peptidase M12A, astacin" CG7631 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0261566 CG42680 http://flybase.net/reports/FBgn0261566.html protein_coding_gene CG42680 16-Dec-15 2015_12 FBgn0265723 CR44530 http://flybase.net/reports/FBgn0265723.html non_protein_coding_gene "lincRNA.420, incRNA.420" CR44530 16-Dec-15 2015_12 FBgn0019878 anon-69Ae anon-69Ae http://flybase.net/reports/FBgn0019878.html gene 16-Dec-15 2015_12 larval stage FBgn0062258 SF-1 SF1 boundary element http://flybase.net/reports/FBgn0062258.html insulator "SF-1, SF1" 16-Dec-15 2015_12 FBgn0004793 crpe crepe http://flybase.net/reports/FBgn0004793.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0033498 CG12209 http://flybase.net/reports/FBgn0033498.html FBgn0063735 protein_coding_gene BcDNA:AT13439 CG12209 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0084000 CG41433 http://flybase.net/reports/FBgn0084000.html FBan0041433 protein_coding_gene 16-Dec-15 2015_12 FBgn0014311 l(3)ry105 lethal (3) ry105 http://flybase.net/reports/FBgn0014311.html FBgn0015507 gene P622 16-Dec-15 2015_12 "lethal,recessive" FBgn0266749 CR45222 http://flybase.net/reports/FBgn0266749.html non_protein_coding_gene CR45222 16-Dec-15 2015_12 FBgn0013500 l(1)MA lethal (1) MA http://flybase.net/reports/FBgn0013500.html gene 16-Dec-15 2015_12 FBgn0265962 CR44749 http://flybase.net/reports/FBgn0265962.html non_protein_coding_gene CR44749 16-Dec-15 2015_12 FBgn0067786 anon-i176 anon-i176 http://flybase.net/reports/FBgn0067786.html gene i176 16-Dec-15 2015_12 FBgn0039339 CG5116 http://flybase.net/reports/FBgn0039339.html protein_coding_gene 0005525=GTP binding Dromel_CG5116_FBtr0084877_mORF "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR030394=HflX-type guanine nucleotide-binding (G) domain, IPR025121=GTPase HflX, N-terminal, IPR006073=GTP binding domain, IPR016496=GTPase HflX" CG5116 16-Dec-15 2015_12 ENSDARG00000061091(wu:fc56b07) WBGene00009769(F46B6.4) ENSXETG00000004125(GTPBP6) ENSMUSG00000033434(Gtpbp6) ENSG00000215634 viable FBgn0052850 CG32850 http://flybase.net/reports/FBgn0052850.html "FBgn0046280, FBgn0062444" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0051865=protein autoubiquitination, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process" 0000151=ubiquitin ligase complex "BEST:GH26713, BcDNA:RE41137, RNF-11" "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG32850 16-Dec-15 2015_12 "ENSDARG00000053742,ENSDARG00000040635(zgc:114095),ENSDARG00000010442(rnf11)" WBGene00007226(C01G6.4) "ENSXETG00000002837(rnf11),ENSXETG00000004769(BC076905.1)" ENSMUSG00000028557(Rnf11) ENSG00000123091(RNF11) "viable,fertile" FBgn0053758 CG33758 http://flybase.net/reports/FBgn0053758.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33758 16-Dec-15 2015_12 FBgn0259654 B0960 http://flybase.net/reports/FBgn0259654.html gene 16-Dec-15 2015_12 visible "wing vein,wing,tarsal segment,unguis" FBgn0028879 CG15270 http://flybase.net/reports/FBgn0028879.html protein_coding_gene 0005227=calcium activated cation channel activity 0006812=cation transport 0005886=plasma membrane "Axs-like, BG:DS04929.1" "IPR031289=Anoctamin-8, IPR007632=Anoctamin" CG15270 16-Dec-15 2015_12 WBGene00013326(Y57G11C.37) ENSXETG00000013077(ANO8) ENSMUSG00000034863(Ano8) ENSG00000074855(ANO8) viable FBgn0026669 l(1)G0129 lethal (1) G0129 http://flybase.net/reports/FBgn0026669.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0031936 CG13794 http://flybase.net/reports/FBgn0031936.html protein_coding_gene "0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity" 0006836=neurotransmitter transport 0016021=integral component of membrane IPR000175=Sodium:neurotransmitter symporter CG13794 16-Dec-15 2015_12 viable FBgn0047330 CG32235 http://flybase.net/reports/FBgn0047330.html FBgn0052235 protein_coding_gene BcDNA:AT25643 CG32235 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0011083 l(1)Q41 lethal (1) Q41 http://flybase.net/reports/FBgn0011083.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0039025 Usp12-46 Ubiquitin-specific protease 12/46 ortholog http://flybase.net/reports/FBgn0039025.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0006511=ubiquitin-dependent protein catabolic process, 0045746=negative regulation of Notch signaling pathway, 0016579=protein deubiquitination" "Q9VCT9, CG7023" "IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG7023 16-Dec-15 2015_12 ENSDARG00000045343(usp46) "YER098W(UBP9),YBL067C(UBP13)" WBGene00011216(usp-46) ENSXETG00000009799(USP12) "ENSMUSG00000029640(Usp12),ENSMUSG00000054814(Usp46)" "ENSG00000152484(USP12),ENSG00000109189(USP46)" viable "mesothoracic tergum,socket,eo sensory structure" FBgn0001629 l(1)dn6 lethal (1) discs normal 6 http://flybase.net/reports/FBgn0001629.html gene l(1)d.norm.-6 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033871 CG13339 http://flybase.net/reports/FBgn0033871.html FBgn0047063 protein_coding_gene BcDNA:RE69336 CG13339 16-Dec-15 2015_12 viable FBgn0046886 Gr98c Gustatory receptor 98c http://flybase.net/reports/FBgn0046886.html "FBgn0039524, FBgn0041221, FBgn0045466, FBgn0045467, FBgn0051060" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG12884, GR98B.3, Gr98A1, GR98c, 98B.3, Gustatory receptor 98B.3, Gustatory receptor 98A2, Gr98B3, Gr98A2, CG31060" IPR013604=7TM chemoreceptor CG31060 16-Dec-15 2015_12 viable FBgn0029720 CG3009 http://flybase.net/reports/FBgn0029720.html protein_coding_gene "0005509=calcium ion binding, 0004623=phospholipase A2 activity" "0016042=lipid catabolic process, 0006644=phospholipid metabolic process" "IPR013090=Phospholipase A2, active site, IPR016090=Phospholipase A2 domain, IPR001211=Phospholipase A2" CG3009 16-Dec-15 2015_12 "viable,fertile" FBgn0267346 T:FK506-bp2 http://flybase.net/reports/FBgn0267346.html engineered_tag 16-Dec-15 2015_12 FBgn0261812 CG42754 http://flybase.net/reports/FBgn0261812.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001120 gnu giant nuclei http://flybase.net/reports/FBgn0001120.html FBgn0036453 protein_coding_gene "0008156=negative regulation of DNA replication, 0007346=regulation of mitotic cell cycle, 0051726=regulation of cell cycle, 0007343=egg activation, 0007067=mitotic nuclear division" "0005634=nucleus, 0005737=cytoplasm" "Gnu, CG5272, Giant nuclei" "IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain" CG5272 16-Dec-15 2015_12 " adult stage && O | stage S>=11 , embryonic stage | 0-1 hr " " oocyte

, organism

" "lethal,maternal effect,recessive,mitotic cell cycle defective,meiotic cell cycle defective,viable" "cleavage nucleus,maternal effect,female pronucleus | maternal effect,polar body nucleus,female,mitotic cell cycle | cleavage stage | maternal effect,cleavage stage embryo,nurse cell & nucleusmat.ë±Tub67C.THsimVP16,ovary,actin filament & nurse cellmat.ë±Tub67C.THsimVP16" FBgn0011671 musculin musculin http://flybase.net/reports/FBgn0011671.html gene 16-Dec-15 2015_12 FBgn0259475 C464 http://flybase.net/reports/FBgn0259475.html gene 16-Dec-15 2015_12 visible wing hair FBgn0022974 snRNP120K snRNP120K http://flybase.net/reports/FBgn0022974.html gene "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" 120K 16-Dec-15 2015_12 FBgn0050115 GEFmeso Guanine nucleotide exchange factor in mesoderm http://flybase.net/reports/FBgn0050115.html "FBgn0034358, FBgn0034359" protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0017160=Ral GTPase binding, 0005089=Rho guanyl-nucleotide exchange factor activity" "0032489=regulation of Cdc42 protein signal transduction, 0007480=imaginal disc-derived leg morphogenesis, 0007474=imaginal disc-derived wing vein specification" "CG30115, GEFmeso, CG5503, CG18430" "IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG30115 16-Dec-15 2015_12 "ENSMUSG00000037552(Plekhg2),ENSMUSG00000052609(Plekhg3)" "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "crossvein,mesoderm,supernumerary" FBgn0264460 CR43868 http://flybase.net/reports/FBgn0264460.html non_protein_coding_gene CR43868 16-Dec-15 2015_12 FBgn0265544 CR44394 http://flybase.net/reports/FBgn0265544.html pseudogene_attribute CR44394 16-Dec-15 2015_12 FBgn0051215 tRNA:CR31215 transfer RNA:CR31215 http://flybase.net/reports/FBgn0051215.html FBgn0060283 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31215, tRNA[[Ala]], chr3R.trna27-AlaAGC, AE002708.trna21-AlaAGC, tRNA:A:AGC:AE002708-f" CR31215 16-Dec-15 2015_12 FBgn0026194 pana pollyanna http://flybase.net/reports/FBgn0026194.html gene 0007067=mitotic nuclear division "fret, free thinker" 16-Dec-15 2015_12 FBgn0260091 2L2676 http://flybase.net/reports/FBgn0260091.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0051148 CG31148 http://flybase.net/reports/FBgn0051148.html "FBgn0039105, FBgn0044636" protein_coding_gene 0004348=glucosylceramidase activity "0006665=sphingolipid metabolic process, 0034620=cellular response to unfolded protein, 0005975=carbohydrate metabolic process" "Glucosylceramidase, anon-WO0140519.234, CG10299, CT28913" "IPR001139=Glycoside hydrolase, family 30, IPR013781=Glycoside hydrolase, catalytic domain, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR017853=Glycoside hydrolase superfamily" CG31148 16-Dec-15 2015_12 "WBGene00021160(Y4C6B.6),WBGene00008706(F11E6.1),WBGene00016335(C33C12.3),WBGene00016340(C33C12.8)" ENSMUSG00000028048(Gba) "ENSG00000177628(GBA),ENSG00000160766" "viable,visible" mesothoracic tergum FBgn0002116 l(2)cg lethal (2) with comb gap http://flybase.net/reports/FBgn0002116.html gene 16-Dec-15 2015_12 lethal FBgn0031607 CG15440 http://flybase.net/reports/FBgn0031607.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" "0000398=mRNA splicing, via spliceosome" "Secp43, cg15440" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG15440 16-Dec-15 2015_12 "ENSDARG00000056475(trnau1apl),ENSDARG00000036015(trnau1ap)" ENSXETG00000014263(TRNAU1AP) ENSMUSG00000028898(Trnau1ap) ENSG00000180098(TRNAU1AP) "partially lethal - majority die,body color defective" mesothoracic tergum FBgn0001084 fy fuzzy http://flybase.net/reports/FBgn0001084.html protein_coding_gene "0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity, 0007163=establishment or maintenance of cell polarity" "CG13396, Fuzzy" IPR026069=Fuzzy protein CG13396 16-Dec-15 2015_12 ENSXETG00000002889(FUZ) ENSMUSG00000011658(Fuz) ENSG00000010361(FUZ) embryonic stage -- adult stage organism

"wild-type,planar polarity defective,viable,visible,recessive" "wing hair,wing hair & 1st posterior cell,wing hair & 3rd posterior cell,wing & trichome,wing cell,macrochaeta,microchaeta & adult thorax,wing margin bristle,microchaeta & leg,bract,trichome,trichogen cell" DRSC03533 K -0.677267405 -0.128713273 -0.429033216 0.283398489 1.524777308 -0.528743578 FBgn0030228 BTBD9 BTB (POZ) domain containing 9 ortholog http://flybase.net/reports/FBgn0030228.html protein_coding_gene "0030674=protein binding, bridging" "0045938=positive regulation of circadian sleep/wake cycle, sleep, 0008344=adult locomotory behavior, 0032225=regulation of synaptic transmission, dopaminergic" "0005737=cytoplasm, 0031463=Cul3-RING ubiquitin ligase complex" "CG1826, dBTBD9" "IPR000210=BTB/POZ domain, IPR000421=Coagulation factor 5/8 C-terminal domain, IPR011333=POZ domain, IPR011705=BTB/Kelch-associated, IPR008979=Galactose-binding domain-like" CG1826 16-Dec-15 2015_12 "ENSDARG00000052839,ENSDARG00000068983(LOC100002616)" WBGene00015463(C05C8.6) ENSXETG00000010760(BTBD9) ENSMUSG00000062202(Btbd9) ENSG00000183826(BTBD9) "viable,short lived,sleep defective,recessive,locomotor behavior defective" DRSC22371 K -0.44672001 0.1189548 -0.571569764 -0.267415836 -1.553329981 -0.269928017 FBgn0038057 CG12267 http://flybase.net/reports/FBgn0038057.html protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" 0006383=transcription from RNA polymerase III promoter 0005666=DNA-directed RNA polymerase III complex "IPR008806=RNA polymerase III Rpc82, C -terminal, IPR013197=RNA polymerase III subunit RPC82-related, helix-turn-helix" CG12267 16-Dec-15 2015_12 ENSDARG00000057562(polr3c) WBGene00016750(C48E7.2) ENSXETG00000018686(POLR3C) ENSMUSG00000028099(Polr3c) ENSG00000186141(POLR3C) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264629 asthmatic asthmatic http://flybase.net/reports/FBgn0264629.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "eye,somatic clone,terminal tracheal cell,embryonic/larval tracheal system" FBgn0000276 CecA1 Cecropin A1 http://flybase.net/reports/FBgn0000276.html protein_coding_gene "0042742=defense response to bacterium, 0050832=defense response to fungus, 0019731=antibacterial humoral response, 0050830=defense response to Gram-positive bacterium, 0048102=autophagic cell death, 0006959=humoral immune response, 0009617=response to bacterium, 0035071=salivary gland cell autophagic cell death, 0050829=defense response to Gram-negative bacterium" "0005576=extracellular region, 0005615=extracellular space" "cecA, crpA1, cecropin, CecropinA1, cecropin A1, Cecropin-A1, cecropin A, cecropinA, cecropinA1, cec, Cecropin, unnamed, CG1365, Cec-A1, Cecropin-A1/A2 precursor, cecA1, CecropinA, Cecropin-A, cecropin-A1, CEC, Cec, Cec A1, CecA, Cecropin A, cecropin-A, DIM 25" "IPR020400=Cecropin, diptera, IPR000875=Cecropin" CG1365 16-Dec-15 2015_12 " pupal stage , larval stage , adult stage " " embryonic/larval hemocyte

, adult fat body

" "viable,body color defective" "adult posterior midgut epithelium,mesothoracic tergum" FBgn0011105 l(1)Q66 lethal (1) Q66 http://flybase.net/reports/FBgn0011105.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0060548 l(3)S098516a lethal (3) S098516a http://flybase.net/reports/FBgn0060548.html gene 0985/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0086449 Cog8 http://flybase.net/reports/FBgn0086449.html gene 16-Dec-15 2015_12 FBgn0263555 mir-4943 mir-4943 stem loop http://flybase.net/reports/FBgn0263555.html miRNA_gene "CR43540, dme-mir-4943" CR43540 16-Dec-15 2015_12 FBgn0015370 charon charon http://flybase.net/reports/FBgn0015370.html gene chn 16-Dec-15 2015_12 FBgn0040605 CG14236 http://flybase.net/reports/FBgn0040605.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000758 fs(1)A462 female sterile (1) A462 http://flybase.net/reports/FBgn0000758.html gene fs(1)462 16-Dec-15 2015_12 "female sterile soma-dependent,recessive" FBgn0011855 tRNA:E4:62Ae transfer RNA:glu4:62Ae http://flybase.net/reports/FBgn0011855.html "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052322, FBgn0060245" tRNA_gene "0033460=GAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002584.trna11-GluCTC, CR32322, glu-trna, tRNA:glu4:62Ae, tRNA:E:CTC:AE002584-i, tRNA:E4, tRNA:Glu, chr3L.trna11-GluCTC" CR32322 16-Dec-15 2015_12 FBgn0028138 l(3)S048318 lethal (3) S048318 http://flybase.net/reports/FBgn0028138.html gene 0483/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0264467 CR43875 http://flybase.net/reports/FBgn0264467.html non_protein_coding_gene CR43875 16-Dec-15 2015_12 FBgn0069249 attP:Dps2 pseudo attP recognition site Dps2 http://flybase.net/reports/FBgn0069249.html region 16-Dec-15 2015_12 FBgn0267249 CR45689 http://flybase.net/reports/FBgn0267249.html non_protein_coding_gene CR45689 16-Dec-15 2015_12 FBgn0010651 MFS14 Major Facilitator Superfamily Transporter 14 http://flybase.net/reports/FBgn0010651.html FBgn0034393 protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity "0048190=wing disc dorsal/ventral pattern formation, 0001666=response to hypoxia, 0055085=transmembrane transport" "0005886=plasma membrane, 0016021=integral component of membrane" "CG15095, l208717, l(2)08717, 8717, lethal(2)08717, MFS14, lethal (2) 08717" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG15095 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,lethal,recessive" FBgn0036188 CG7339 http://flybase.net/reports/FBgn0036188.html protein_coding_gene 0003899=DNA-directed RNA polymerase activity "0006383=transcription from RNA polymerase III promoter, 0022008=neurogenesis" 0005666=DNA-directed RNA polymerase III complex lincRNA.S4825 "IPR012340=Nucleic acid-binding, OB-fold, IPR005576=RNA polymerase Rpb7, N-terminal, IPR013238=RNA polymerase III, subunit Rpc25" CG7339 16-Dec-15 2015_12 ENSDARG00000038399 YKL144C(RPC25) WBGene00014111(ZK856.10) ENSMUSG00000022476(Polr3h) ENSG00000100413(POLR3H) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0035407 Asciz ASCIZ homolog http://flybase.net/reports/FBgn0035407.html protein_coding_gene 0046872=metal ion binding "0007088=regulation of mitotic nuclear division, 0045944=positive regulation of transcription from RNA polymerase II promoter" "CG14962, dASCIZ" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG14962 16-Dec-15 2015_12 ENSXETG00000000183(ATMIN) ENSMUSG00000047388(Atmin) ENSG00000166454(ATMIN) "visible,mitotic cell cycle defective,increased cell death,lethal - all die during first instar larval stage,viable" "wing,posterior compartment,wing disc,somatic clone" FBgn0005118 l(1)FMb lethal (1) FMb http://flybase.net/reports/FBgn0005118.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065938 l(2)SH0120 lethal (2) SH0120 http://flybase.net/reports/FBgn0065938.html gene l(2)SH2 0120 16-Dec-15 2015_12 "lethal,recessive" FBgn0036778 Cyp312a1 Cyp312a1 http://flybase.net/reports/FBgn0036778.html protein_coding_gene "0004497=monooxygenase activity, 0005506=iron ion binding, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "cytochrome P450, CG5137, P450 IV, 312a1" "IPR001128=Cytochrome P450, IPR002403=Cytochrome P450, E-class, group IV" CG5137 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0005293 mei-2245 meiotic 2245 http://flybase.net/reports/FBgn0005293.html gene 2245 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0040909 CG12686 http://flybase.net/reports/FBgn0040909.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039500 CG5984 http://flybase.net/reports/FBgn0039500.html protein_coding_gene 0003779=actin binding "0030154=cell differentiation, 0030036=actin cytoskeleton organization" Filamin-like "IPR013783=Immunoglobulin-like fold, IPR029874=Filamin-B, IPR001298=Filamin/ABP280 repeat, IPR014756=Immunoglobulin E-set, IPR017868=Filamin/ABP280 repeat-like" CG5984 16-Dec-15 2015_12 FBgn0053234 CG33234 http://flybase.net/reports/FBgn0053234.html FBgn0035365 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane CG12036 "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG33234 16-Dec-15 2015_12 FBgn0085271 CG34242 http://flybase.net/reports/FBgn0085271.html protein_coding_gene IPR027917=Protein of unknown function DUF4538 CG34242 16-Dec-15 2015_12 FBgn0000846 fs(1)M33 female sterile (1) M33 http://flybase.net/reports/FBgn0000846.html gene 16-Dec-15 2015_12 female sterile chorion FBgn0061027 l(3)S024706b lethal (3) S024706b http://flybase.net/reports/FBgn0061027.html gene 0247/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0266175 pre-mod(mdg4)-P http://flybase.net/reports/FBgn0266175.html protein_coding_gene CG44881 "IPR007588=Zinc finger, FLYWCH-type" CG44881 16-Dec-15 2015_12 FBgn0014903 CG14630 http://flybase.net/reports/FBgn0014903.html FBgn0029555 protein_coding_gene 0008336=gamma-butyrobetaine dioxygenase activity 0055114=oxidation-reduction process "Transcription unit B, anon-1Eb, B, EG:BACR7A4.9" "IPR007175=RNAse P, Rpr2/Rpp21 subunit, IPR003819=TauD/TfdA-like domain, IPR010376=Domain of unknown function DUF971" CG14630 16-Dec-15 2015_12 ENSDARG00000036135(bbox1) YHL021C(AIM17) WBGene00001522(gbh-1) ENSXETG00000004606(BBOX1) ENSMUSG00000041660(Bbox1) ENSG00000129151(BBOX1) DRSC18166 I 2.419458636 0.134205101 0.826608037 0.346478239 -0.77077799 0.093511441 FBgn0010213 Sod2 Superoxide dismutase 2 (Mn) http://flybase.net/reports/FBgn0010213.html protein_coding_gene "0016209=antioxidant activity, 0004784=superoxide dismutase activity, 0046872=metal ion binding" "0055114=oxidation-reduction process, 0072593=reactive oxygen species metabolic process, 0019430=removal of superoxide radicals, 0038001=paracrine signaling, 0035206=regulation of hemocyte proliferation, 0006801=superoxide metabolic process, 1903146=regulation of mitochondrion degradation, 0008340=determination of adult lifespan, 0019222=regulation of metabolic process, 0003007=heart morphogenesis" 0005759=mitochondrial matrix "mitochodnrial SOD, Mn SOD, manganese superoxide dismutase, SOD, SOD-2, Mn-superoxide dismutase, MnSODII, Mito SOD, Manganese Superoxide Dismutase, SOD2, superoxide dismutase-2, mnSOD, Superoxide dismutase, Mn-SOD, sod2, dSOD2, mitSOD2, superoxide dismutase, Sod-2, manganese-SOD, Mn-SOD2, mitochondrial superoxide dismutase 2, MnSOD, mitochondrial Mn-superoxide dismutase 2, CG8905, mitochondrial MnSOD, Superoxide dismutatase 2, Superoxide Dismutase 2, dSod2, Mn[2+]SOD, Superoxide dismutase 2, superoxide dismutase 2, Mn superoxide dismutase" "IPR019833=Manganese/iron superoxide dismutase, binding site, IPR019832=Manganese/iron superoxide dismutase, C-terminal, IPR001189=Manganese/iron superoxide dismutase, IPR019831=Manganese/iron superoxide dismutase, N-terminal" CG8905 16-Dec-15 2015_12 ENSDARG00000042644(sod2) YHR008C(SOD2) "WBGene00004931(sod-2),WBGene00004932(sod-3)" ENSXETG00000021180(sod2) ENSMUSG00000006818(Sod2) ENSG00000112096(SOD2) "short lived,tetracycline conditional,long lived,heat sensitive,viable,fertile,dominant,chemical sensitive,recessive,stress response defective,locomotor behavior defective,behavior defective,smell perception defective,gravitaxis defective,increased cell death,lethal,some die during immature adult stage,decreased cell number,conditional,oxidative stress response defective,bang sensitive,progressive,neuroanatomy defective" "adult heart,adult brain,lamellocyte,conditional,embryonic/larval motor neuron" DRSC07554 E -0.018967043 0.145473639 -1.958978767 0.477877685 0.162888548 0.129518469 FBgn0265914 CR44703 http://flybase.net/reports/FBgn0265914.html non_protein_coding_gene CR44703 16-Dec-15 2015_12 FBgn0028995 ponderosa ponderosa http://flybase.net/reports/FBgn0028995.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 dendrite | dorsal | embryonic stage FBgn0001692 l(1)ESHS13 lethal (1) ESHS13 http://flybase.net/reports/FBgn0001692.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004085 Ec3 Ecysone-induced RNA 3 http://flybase.net/reports/FBgn0004085.html gene 16-Dec-15 2015_12 FBgn0043480 l(3)66EFf lethal (3) 66EFf http://flybase.net/reports/FBgn0043480.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034183 CG9642 http://flybase.net/reports/FBgn0034183.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression IPR001214=SET domain CG9642 16-Dec-15 2015_12 viable FBgn0043035 l(2)42Bi lethal (2) 42Bi http://flybase.net/reports/FBgn0043035.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052512 CG32512 http://flybase.net/reports/FBgn0052512.html "FBgn0031151, FBgn0031152" protein_coding_gene "CG1739, CG15447" IPR025423=Domain of unknown function DUF4149 CG32512 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0264857 iab-8 iab-8 non-coding RNA http://flybase.net/reports/FBgn0264857.html "FBgn0027340, FBgn0263610, FBgn0051270, FBgn0262906" non_protein_coding_gene "iab-8, CR43261, male specific abdominal, infraabdominal-8, mpa, miR-iab-8, msa, CG31270, iab-8 ncRNA, iab" CR43261 16-Dec-15 2015_12 "male sterile,female sterile" FBgn0034136 DAT Dopamine transporter http://flybase.net/reports/FBgn0034136.html protein_coding_gene "0005330=dopamine:sodium symporter activity, 0019811=cocaine binding, 0005329=dopamine transmembrane transporter activity" "0015872=dopamine transport, 0006836=neurotransmitter transport, 0042745=circadian sleep/wake cycle, 0030431=sleep" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "fumin, dDAT, DmDAT, CG8380, dopamine transporter, fmn" IPR000175=Sodium:neurotransmitter symporter CG8380 16-Dec-15 2015_12 ENSDARG00000016141(LOC565776) WBGene00000934(dat-1) "ENSXETG00000001728(SLC6A3),ENSXETG00000002785(SLC6A2)" "ENSMUSG00000055368(Slc6a2),ENSMUSG00000021609(Slc6a3)" "ENSG00000103546(SLC6A2),ENSG00000142319(SLC6A3)" "behavior defective,hyperactive,chemical conditional,locomotor behavior defective,circadian rhythm defective,viable,fertile,sleep defective,visible" mesothoracic tergum FBgn0016072 su(wa)::tra su(wa)::tra http://flybase.net/reports/FBgn0016072.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0046776 CR14033 http://flybase.net/reports/FBgn0046776.html "FBgn0040946, FBgn0046777" pseudogene_attribute "CG14033, BcDNA:LD26231, BcDNA:LD26673" CR14033 16-Dec-15 2015_12 viable DRSC02358 E 1.184358107 0.841403925 1.551278363 3.273890028 0.536744075 0.112569003 FBgn0259657 B2037 http://flybase.net/reports/FBgn0259657.html gene 16-Dec-15 2015_12 visible "leg,proximal,scutellum" FBgn0036164 CG7543 http://flybase.net/reports/FBgn0036164.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0065285 l(2)SH2022 lethal (2) SH2022 http://flybase.net/reports/FBgn0065285.html gene l(2)SH2 2022 16-Dec-15 2015_12 "lethal,recessive" FBgn0029074 l(1)G0145 lethal (1) G0145 http://flybase.net/reports/FBgn0029074.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0022893 Df31 Decondensation factor 31 http://flybase.net/reports/FBgn0022893.html "FBgn0015041, FBgn0022155, FBgn0022348, FBgn0025987, FBgn0026586, FBgn0027759, FBgn0045899, FBtr0085919, FBtr0085920, FBpp0085274" protein_coding_gene 0042393=histone binding "0006334=nucleosome assembly, 0006325=chromatin organization" "0005737=cytoplasm, 0005634=nucleus, 0000785=chromatin, 0005886=plasma membrane" "DF31, anon1A4, anon-EST:Liang-1.46, clone 1.46, l(2)k05815, Chromatin decondensation factor 31, anon-EST:fe1A4, LD04967, anon-WO0153538.53, anon-fast-evolving-1A4, DF 31, CG2207, anon-EST:Posey126, BEST:LD04967" CG2207 16-Dec-15 2015_12 "viable,lethal,recessive,long lived,wild-type,partially lethal - majority die" chromatin FBgn0260599 2L2718 http://flybase.net/reports/FBgn0260599.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0267961 CR46241 http://flybase.net/reports/FBgn0267961.html non_protein_coding_gene lincRNA.522 CR46241 16-Dec-15 2015_12 FBgn0027615 CG6404 http://flybase.net/reports/FBgn0027615.html protein_coding_gene 0008565=protein transporter activity "0051205=protein insertion into membrane, 0008535=respiratory chain complex IV assembly" "0005740=mitochondrial envelope, 0005743=mitochondrial inner membrane, 0016021=integral component of membrane" "BcDNA:GH02220, Biogenesis protein OXA1, Inner membrane protein OXA1L, OXA1" "IPR001708=Membrane insertase OXA1/ALB3/YidC, IPR028055=Membrane insertase YidC/Oxa1, C-terminal" CG6404 16-Dec-15 2015_12 ENSDARG00000069313(oxa1l) YER154W(OXA1) WBGene00007215(C01A2.3) ENSXETG00000022127(OXA1L) ENSMUSG00000000959(Oxa1l) ENSG00000155463(OXA1L) DRSC09672 K 0.320060997 -0.359578719 -0.163800958 0.243142942 0.603791233 1.713725377 FBgn0011748 anon-M-SAR anonymous M/SAR sequence http://flybase.net/reports/FBgn0011748.html repeat_region "anon-M/SAR, centromere; lamin. centromeric beta-heterochromatin sequence" 16-Dec-15 2015_12 FBgn0266990 CR45441 http://flybase.net/reports/FBgn0266990.html non_protein_coding_gene CR45441 16-Dec-15 2015_12 FBgn0050073 Obp50b Odorant-binding protein 50b http://flybase.net/reports/FBgn0050073.html FBgn0033930 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG30073, CG13940, DmelObp50b" CG30073 16-Dec-15 2015_12 viable FBgn0065477 l(2)SH1297 lethal (2) SH1297 http://flybase.net/reports/FBgn0065477.html gene l(2)SH2 1297 16-Dec-15 2015_12 "lethal,recessive" FBgn0034417 CG15117 http://flybase.net/reports/FBgn0034417.html protein_coding_gene 0004566=beta-glucuronidase activity "0005975=carbohydrate metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "IPR006101=Glycoside hydrolase, family 2, IPR008979=Galactose-binding domain-like, IPR006102=Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR023232=Glycoside hydrolase, family 2, active site, IPR013781=Glycoside hydrolase, catalytic domain, IPR006104=Glycosyl hydrolases family 2, sugar binding domain, IPR013812=Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain, IPR023230=Glycoside hydrolase, family 2, conserved site, IPR017853=Glycoside hydrolase superfamily, IPR006103=Glycoside hydrolase family 2, catalytic domain" CG15117 16-Dec-15 2015_12 ENSDARG00000063126(gusb) WBGene00013693(Y105E8B.9) ENSXETG00000010042() ENSMUSG00000025534(Gusb) ENSG00000169919(GUSB) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC06539 I -1.963157371 -1.045937417 -0.339340485 0.770838827 -0.984755744 -1.248662544 FBgn0033788 CG13323 http://flybase.net/reports/FBgn0033788.html protein_coding_gene FBgn0033788 CG13323 16-Dec-15 2015_12 viable FBgn0264368 CR43820 http://flybase.net/reports/FBgn0264368.html non_protein_coding_gene CR43820 16-Dec-15 2015_12 FBgn0067328 3N5 3N5 http://flybase.net/reports/FBgn0067328.html gene 0035220=wing disc development 16-Dec-15 2015_12 "visible,somatic clone" "wing,posterior compartment,somatic clone" FBgn0030629 CG9123 http://flybase.net/reports/FBgn0030629.html protein_coding_gene 0005515=protein binding 0008283=cell proliferation 0005730=nucleolus "IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG9123 16-Dec-15 2015_12 ENSDARG00000044488(zgc:56683) YKL021C(MAK11) ENSXETG00000001072(PAK1IP1) ENSMUSG00000038683(Pak1ip1) ENSG00000111845(PAK1IP1) viable FBgn0086058 snoRNA:Me18S-G1189 http://flybase.net/reports/FBgn0086058.html snoRNA_gene "CR34687, Me18S-Gm1189" CR34687 16-Dec-15 2015_12 FBgn0027584 CG4757 http://flybase.net/reports/FBgn0027584.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "BcDNA:GH05741, GH05741, GH05702" "IPR019826=Carboxylesterase type B, active site, IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG4757 16-Dec-15 2015_12 "ENSDARG00000041595(ces3),ENSDARG00000041569(ces2),ENSDARG00000070915" "ENSMUSG00000031877(2210023G05Rik),ENSMUSG00000061825(Ces2),ENSMUSG00000050097(BC015286),ENSMUSG00000031884(Gm9756),ENSMUSG00000031886(Ces5),ENSMUSG00000055730(Ces6),ENSMUSG00000062826(2310038E17Rik),ENSMUSG00000056973(Ces3),ENSMUSG00000061959(Es22),ENSMUSG00000057074(Ces1),ENSMUSG00000057400(Es1),ENSMUSG00000078964(Gm5158),ENSMUSG00000031725(AU018778),ENSMUSG00000071047(Gm4976),ENSMUSG00000074156(2310039D24Rik),ENSMUSG00000069922(Es31),ENSMUSG00000062181(Gm4738),ENSMUSG00000060560(Ces8),ENSMUSG00000058019(Ces7)" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0063389 snoRNA:Me18S-G1620 http://flybase.net/reports/FBgn0063389.html snoRNA_gene "snoRNA:U25:30E, Me18S-G1620(U25), Dm_18S.007, snoRNA:U25, DmSnR56, U25snoRNA, CR32874" CR32874 16-Dec-15 2015_12 FBgn0267024 CR45468 http://flybase.net/reports/FBgn0267024.html non_protein_coding_gene CR45468 16-Dec-15 2015_12 FBgn0060404 l(3)S131010 lethal (3) S131010 http://flybase.net/reports/FBgn0060404.html gene 1310/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0013457 fs(2)neo5 fs(2)neo5 http://flybase.net/reports/FBgn0013457.html gene unnamed 16-Dec-15 2015_12 "female sterile,lethal,maternal effect" FBgn0259973 Sfp79B Seminal fluid protein 79 http://flybase.net/reports/FBgn0259973.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG42483, Seminal fluid protein 79B" CG42483 16-Dec-15 2015_12 FBgn0267763 CR46094 http://flybase.net/reports/FBgn0267763.html non_protein_coding_gene CR46094 16-Dec-15 2015_12 FBgn0033799 GLaz Glial Lazarillo http://flybase.net/reports/FBgn0033799.html protein_coding_gene "0009267=cellular response to starvation, 0008340=determination of adult lifespan, 0034599=cellular response to oxidative stress" 0005615=extracellular space "CG4604, glial Lazarillo, DGLaz, glial lazarillo" "IPR012674=Calycin, IPR000566=Lipocalin/cytosolic fatty-acid binding domain, IPR022271=Lipocalin, ApoD type, IPR011038=Calycin-like" CG4604 16-Dec-15 2015_12 "viable,fertile,stress response defective,short lived,locomotor behavior defective,increased cell death,chemical sensitive,long lived,heat sensitive,hyperactive" "adult brain,adult nervous system,adult fat body" FBgn0040388 boi brother of ihog http://flybase.net/reports/FBgn0040388.html "FBgn0029618, FBgn0029619, FBgn0052796" protein_coding_gene "0007224=smoothened signaling pathway, 0008589=regulation of smoothened signaling pathway, 0035017=cuticle pattern formation, 0008284=positive regulation of cell proliferation, 0048749=compound eye development, 0001751=compound eye photoreceptor cell differentiation, 0007219=Notch signaling pathway, 0035222=wing disc pattern formation, 0007155=cell adhesion, 0007476=imaginal disc-derived wing morphogenesis" 0009986=cell surface "CG7894, Brother of ihog, brother of iHog, CG32796, CG13756, Brother of Ihog, Boi, brother of ihog, CT23737, EG:BACH59J11.2, CT33235" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013151=Immunoglobulin" CG32796 16-Dec-15 2015_12 ENSDARG00000061328(cdon) ENSXETG00000000029(CDON) "ENSMUSG00000038119(Cdon),ENSMUSG00000022687(Boc)" "ENSG00000064309(CDON),ENSG00000144857(BOC)" "viable,fertile,hyperplasia,visible" "follicle stem cell,wing vein,ectopic,wing blade,interfollicle cell,follicle cell" FBgn0053632 CG33632 http://flybase.net/reports/FBgn0053632.html protein_coding_gene CR33632 IPR010512=Protein of unknown function DUF1091 CG33632 16-Dec-15 2015_12 FBgn0039240 CG3744 http://flybase.net/reports/FBgn0039240.html protein_coding_gene "0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0016020=membrane "IPR029058=Alpha/Beta hydrolase fold, IPR002469=Dipeptidylpeptidase IV, N-terminal domain, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain" CG3744 16-Dec-15 2015_12 ENSDARG00000052606(zgc:152900) WBGene00001056(dpf-3) "ENSXETG00000022083(DPP9),ENSXETG00000006646(DPP8)" "ENSMUSG00000032393(Dpp8),ENSMUSG00000001229(Dpp9)" "ENSG00000142002(DPP9),ENSG00000074603(DPP8)" "viable,fertile" FBgn0083970 CG34134 http://flybase.net/reports/FBgn0083970.html protein_coding_gene CG8475 CG34134 16-Dec-15 2015_12 FBgn0263442 CR43465 http://flybase.net/reports/FBgn0263442.html non_protein_coding_gene CR43465 16-Dec-15 2015_12 FBgn0259635 B0426 http://flybase.net/reports/FBgn0259635.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" proboscis FBgn0031263 Tspo Translocator protein http://flybase.net/reports/FBgn0031263.html FBgn0025550 protein_coding_gene 0008503=benzodiazepine receptor activity "0008340=determination of adult lifespan, 0002082=regulation of oxidative phosphorylation, 0043065=positive regulation of apoptotic process" "0005740=mitochondrial envelope, 0016021=integral component of membrane, 0005741=mitochondrial outer membrane" "dTSPO, tspo, CG2789, anon-EST:Posey116" IPR004307=TspO/MBR-related protein CG2789 16-Dec-15 2015_12 ENSDARG00000026655(tspo) WBGene00077771(C41G7.9) ENSXETG00000012276(TSPO) ENSMUSG00000041736(Tspo) ENSG00000100300(TSPO) viable FBgn0025476 pogo\T pogo transposase http://flybase.net/reports/FBgn0025476.html transposable_element_gene PogoR11 16-Dec-15 2015_12 FBgn0043581 MESK1 Misexpression Suppressor of KDN 1 http://flybase.net/reports/FBgn0043581.html gene 0046579=positive regulation of Ras protein signal transduction 16-Dec-15 2015_12 viable FBgn0003359 sesA stress-sensitive A http://flybase.net/reports/FBgn0003359.html gene "0007629=flight behavior, 0009612=response to mechanical stimulus" 16-Dec-15 2015_12 "lethal,heat sensitive,bang sensitive,flight defective,behavior defective" FBgn0036117 CG6321 http://flybase.net/reports/FBgn0036117.html protein_coding_gene "0003824=catalytic activity, 0030170=pyridoxal phosphate binding" 0009058=biosynthetic process "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015424=Pyridoxal phosphate-dependent transferase, IPR004839=Aminotransferase, class I/classII" CG6321 16-Dec-15 2015_12 ENSDARG00000011410 YER152C() ENSXETG00000023143(Aadat) ENSMUSG00000057228(Aadat) ENSG00000109576(AADAT) "viable,fertile" FBgn0262961 CG43272 http://flybase.net/reports/FBgn0262961.html protein_coding_gene lincRNA.337 CG43272 16-Dec-15 2015_12 FBgn0051824 CR31824 http://flybase.net/reports/FBgn0051824.html FBgn0032574 pseudogene_attribute "CG18629, CG31824" CR31824 16-Dec-15 2015_12 FBgn0034943 Fmo-1 Flavin-containing monooxygenase 1 http://flybase.net/reports/FBgn0034943.html protein_coding_gene "0004497=monooxygenase activity, 0050661=NADP binding, 0050660=flavin adenine dinucleotide binding, 0004499=N,N-dimethylaniline monooxygenase activity" 0055114=oxidation-reduction process "0005739=mitochondrion, 0005829=cytosol, 0043231=intracellular membrane-bounded organelle" "DmFMO-1, CG3006, FMO-1" "IPR020946=Flavin monooxygenase-like, IPR000960=Flavin monooxygenase FMO" CG3006 16-Dec-15 2015_12 "ENSDARG00000039211(zgc:77439),ENSDARG00000069158,ENSDARG00000069333(LOC793236)" YHR176W(FMO1) "WBGene00007254(C01H6.4),WBGene00016728(C46H11.2)" ENSXETG00000009098() "ENSMUSG00000051081(Gm4847),ENSMUSG00000026691(Fmo3),ENSMUSG00000026560(Fmo9),ENSMUSG00000040170(Fmo2),ENSMUSG00000040181(Fmo1),ENSMUSG00000028088(Fmo5),ENSMUSG00000026692(Fmo4)" "ENSG00000117507,ENSG00000007933(FMO3),ENSG00000010932(FMO1),ENSG00000094963(FMO2),ENSG00000076258(FMO4),ENSG00000131781(FMO5)" "partially lethal - majority die,some die during pupal stage" FBgn0051773 CG31773 http://flybase.net/reports/FBgn0051773.html FBgn0031577 protein_coding_gene "0004326=tetrahydrofolylpolyglutamate synthase activity, 0005524=ATP binding" 0009396=folic acid-containing compound biosynthetic process CG3390 "IPR001645=Folylpolyglutamate synthetase, IPR023600=Folylpolyglutamate synthase, eukaryota, IPR013221=Mur ligase, central" CG31773 16-Dec-15 2015_12 DRSC00600 IK 1.751746241 0.045667974 0.791412586 0.738587127 0.297718222 1.563776233 FBgn0083093 curta curta http://flybase.net/reports/FBgn0083093.html gene 16-Dec-15 2015_12 FBgn0050268 CG30268 http://flybase.net/reports/FBgn0050268.html FBgn0034771 protein_coding_gene CG13520 CG30268 16-Dec-15 2015_12 ENSG00000089101(C20orf26) viable FBgn0020585 anon-57Cl anon-57Cl http://flybase.net/reports/FBgn0020585.html gene unnamed 16-Dec-15 2015_12 FBgn0037215 ë_-Man ë_-Mannosidase http://flybase.net/reports/FBgn0037215.html "FBan0012582, FBgn0037216" protein_coding_gene 0004567=beta-mannosidase activity 0046355=mannan catabolic process "CG12583, beta-Man, beta-Mannosidase, CG12582" "IPR008979=Galactose-binding domain-like, IPR006102=Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR013781=Glycoside hydrolase, catalytic domain, IPR013812=Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain, IPR017853=Glycoside hydrolase superfamily, IPR028369=Beta mannosidase" CG12582 16-Dec-15 2015_12 ENSDARG00000008238(manba) WBGene00007904(C33G3.4) ENSXETG00000002247(MANBA) ENSMUSG00000028164(Manba) ENSG00000109323(MANBA) viable FBgn0053368 5SrRNA:CR33368 5SrRNA:CR33368 http://flybase.net/reports/FBgn0053368.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33368 CR33368 16-Dec-15 2015_12 FBgn0020426 HLH44A HLH44A http://flybase.net/reports/FBgn0020426.html gene 0003700=sequence-specific DNA binding transcription factor activity 0005634=nucleus 44A 16-Dec-15 2015_12 FBgn0000403 Cy Curly http://flybase.net/reports/FBgn0000403.html gene 0007476=imaginal disc-derived wing morphogenesis l(2)23Bb 16-Dec-15 2015_12 "lethal,wild-type" wing FBgn0266170 pre-mod(mdg4)-C http://flybase.net/reports/FBgn0266170.html protein_coding_gene CG44876 IPR018379=BEN domain CG44876 16-Dec-15 2015_12 FBgn0026577 CG8677 http://flybase.net/reports/FBgn0026577.html "FBgn0032936, FBgn0046270" protein_coding_gene 0008270=zinc ion binding "0045892=negative regulation of transcription, DNA-templated, 0070868=heterochromatin organization involved in chromatin silencing" "0005705=polytene chromosome interband, 0005700=polytene chromosome, 0031213=RSF complex, 0005634=nucleus" "BEST:LD19244, dRsf-1, Remodeling and spacing factor, BEST:LD14959, LD14959, HBXAP ortholog" "IPR018501=DDT domain superfamily, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR019787=Zinc finger, PHD-finger, IPR001965=Zinc finger, PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG8677 16-Dec-15 2015_12 ENSG00000099954(CECR2) "long lived,partially lethal - majority die,lethal,viable,fertile,suppressor of variegation,dominant" DRSC21844 IE -0.269192362 2.43078016 1.203768388 1.516851112 -0.347434054 -0.989099814 FBgn0044451 EP682 EP682 http://flybase.net/reports/FBgn0044451.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0040076 primo-2 primo-2 http://flybase.net/reports/FBgn0040076.html "FBgn0038174, FBgn0051311, FBgn0053747, FBtr0082839, FBpp0082304, FBtr0082840, FBpp0082305, FBtr0082841, FBpp0082306, FBtr0082842, FBpp0082307, FBtr0082843, FBpp0082308" protein_coding_gene "0004726=non-membrane spanning protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0003993=acid phosphatase activity" 0006470=protein dephosphorylation 0005737=cytoplasm "Primo-2, LMW-PTP, primo, CG31311, CG9599, CG33747, BEO2" "IPR023485=Phosphotyrosine protein phosphatase I superfamily, IPR017867=Protein-tyrosine phosphatase, low molecular weight, IPR002115=Protein-tyrosine phosphatase, low molecular weight, mammalian" CG33747 16-Dec-15 2015_12 "ENSDARG00000070328(acp1),ENSDARG00000003891(LOC100330515)" YPR073C(LTP1) WBGene00022379(Y94H6A.7) ENSXETG00000027987(Q6DEU0_XENTR) ENSMUSG00000044573(Acp1) ENSG00000143727(ACP1) " embryonic stage , adult stage " " neuron &&of ventral nerve cord

, neuron &&of ventral nerve cord

, embryonic head

, embryonic epidermis | vicinity of

, embryonic/larval digestive system | restricted

" "viable,fertile" FBgn0060479 l(3)S111105 lethal (3) S111105 http://flybase.net/reports/FBgn0060479.html gene 1111/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0047199 CG31517 http://flybase.net/reports/FBgn0047199.html FBgn0051517 protein_coding_gene BcDNA:LD34214 CG31517 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0031901 CG13785 http://flybase.net/reports/FBgn0031901.html protein_coding_gene 16-Dec-15 2015_12 DRSC02288 K -0.180250639 -0.230306034 -0.41107337 0.3600402 -1.696993814 -0.554800955 FBgn0026174 SkpD SKP1-related D http://flybase.net/reports/FBgn0026174.html "FBgn0031072, FBgn0047345" protein_coding_gene 0004842=ubiquitin-protein transferase activity 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "BcDNA:AT18217, dskpD, skpD, SkpD, Skp, CG12700" "IPR001232=S-phase kinase-associated protein 1-like, IPR016073=SKP1 component, POZ domain, IPR016897=S-phase kinase-associated protein 1, IPR011333=POZ domain, IPR016072=SKP1 component, dimerisation" CG12700 16-Dec-15 2015_12 YDR328C(SKP1) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0023135 WppH White prepupal locus H http://flybase.net/reports/FBgn0023135.html gene "9, 22B, 36" 16-Dec-15 2015_12 FBgn0050251 tRNA:CR30251 transfer RNA:CR30251 http://flybase.net/reports/FBgn0050251.html FBgn0060207 tRNA_gene 0033426=CAC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR30251, chr2R.trna78-HisGTG, tRNA:H:GTG:AE002787-b, AE002787.trna19-HisGTG, tRNA[His]" CR30251 16-Dec-15 2015_12 FBgn0028644 beat-Ic beaten path Ic http://flybase.net/reports/FBgn0028644.html FBgn0032580 protein_coding_gene "0016198=axon choice point recognition, 0007415=defasciculation of motor neuron axon, 0007155=cell adhesion, 0007411=axon guidance, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules" "0005576=extracellular region, 0005887=integral component of plasma membrane" "beat-C, BG:DS00913.1, CG4838, Beat-Ic, CT15531, beat Ic" "IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain" CG4838 16-Dec-15 2015_12 "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "intersegmental nerve,transverse nerve,RP3 motor neuron,RP1 motor neuron" DRSC03491 I -0.689103294 -1.766771426 -1.232159393 -0.915894067 0.44087451 -0.574603779 FBgn0264829 CG44037 http://flybase.net/reports/FBgn0264829.html protein_coding_gene CG44037 16-Dec-15 2015_12 FBgn0067096 H84 H84 http://flybase.net/reports/FBgn0067096.html gene 16-Dec-15 2015_12 "lethal,viable" FBgn0260436 CG42531 http://flybase.net/reports/FBgn0260436.html protein_coding_gene CG42531 16-Dec-15 2015_12 FBgn0067810 anon-N1 anon-N1 http://flybase.net/reports/FBgn0067810.html gene N1 16-Dec-15 2015_12 FBgn0062978 CG31808 http://flybase.net/reports/FBgn0062978.html FBgn0051808 protein_coding_gene "CR31808, mRNA-like ncRNA in embryogenesis 33, MRE33, RE70695, BcDNA:RE70695" CG31808 16-Dec-15 2015_12 FBgn0000915 fs(1)ne1 female sterile (1) no eggs 1 http://flybase.net/reports/FBgn0000915.html gene "ne1, fs(1)ne[1]" 16-Dec-15 2015_12 "female sterile,recessive,female sterile soma-dependent" "oocyte,endochorion,stage S10A oocyte,stage S10B oocyte,dorsal appendage,chorion" FBgn0036768 CG7402 http://flybase.net/reports/FBgn0036768.html protein_coding_gene 0003943=N-acetylgalactosamine-4-sulfatase activity 0008152=metabolic process "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR024607=Sulfatase, conserved site, IPR017850=Alkaline-phosphatase-like, core domain, IPR000917=Sulfatase" CG7402 16-Dec-15 2015_12 ENSDARG00000063359(LOC563783) WBGene00006310(sul-3) "ENSXETG00000015525(ARSJ),ENSXETG00000000542(ARSB),ENSXETG00000011881(ARSI)" "ENSMUSG00000042082(Arsb),ENSMUSG00000036412(Arsi),ENSMUSG00000046561(Arsj)" "ENSG00000183876(ARSI),ENSG00000113273(ARSB),ENSG00000180801(ARSJ)" "viable,fertile" FBgn0259255 EP-469.2 http://flybase.net/reports/FBgn0259255.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta,ectopic" FBgn0051602 tRNA:CR31602 transfer RNA:CR31602 http://flybase.net/reports/FBgn0051602.html "FBgn0011843, FBgn0060263" tRNA_gene "0033458=GAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2L.trna15-AspGTC, tRNA:D:GTC:AE002690-b, Asp-tRNA, CR31602, tRNA:D2:29E, tRNA:asp2:29E, tRNA[[Asp]], transfer RNA:asp2:29E, tRNA[Asp-GTC], AE002690.trna6-AspGTC" CR31602 16-Dec-15 2015_12 FBgn0005217 l(3)ET8 lethal Elaine Tasaka 8 http://flybase.net/reports/FBgn0005217.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0083017 snoRNA:ë¬18S-841c snoRNA:ë¬18S-841c http://flybase.net/reports/FBgn0083017.html snoRNA_gene "chr2R:16838224..16838314, psi18S-841c, Psi18S-841c, CR34553" CR34553 16-Dec-15 2015_12 FBgn0037382 Hpr1 Hpr1 http://flybase.net/reports/FBgn0037382.html protein_coding_gene "0007165=signal transduction, 0031990=mRNA export from nucleus in response to heat stress, 0006406=mRNA export from nucleus" "0000347=THO complex, 0005654=nucleoplasm, 0005634=nucleus, 0043234=protein complex" "HPR1, CG2031" "IPR021861=THO complex, subunit THOC1, IPR000488=Death domain, IPR011029=Death-like domain" CG2031 16-Dec-15 2015_12 ENSDARG00000011938 WBGene00020172(thoc-1) ENSXETG00000003155(thoc1) ENSMUSG00000024287(Thoc1) ENSG00000079134(THOC1) viable DRSC12296 I 1.628419054 0.724526984 -0.937161093 -0.094311899 0.863421026 0.11575848 FBgn0267291 CR45727 http://flybase.net/reports/FBgn0267291.html non_protein_coding_gene CR45727 16-Dec-15 2015_12 FBgn0015727 Est-F Est-F http://flybase.net/reports/FBgn0015727.html gene 0052689=carboxylic ester hydrolase activity Est-Fs 16-Dec-15 2015_12 FBgn0046668 anon-38C.29 anon-38C.29 http://flybase.net/reports/FBgn0046668.html gene 38C.29 16-Dec-15 2015_12 FBgn0014314 l(3)ry114 lethal (3) ry114 http://flybase.net/reports/FBgn0014314.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065325 l(2)SH1898 lethal (2) SH1898 http://flybase.net/reports/FBgn0065325.html gene l(2)SH2 1898 16-Dec-15 2015_12 "lethal,recessive" FBgn0031626 CG15631 http://flybase.net/reports/FBgn0031626.html protein_coding_gene CG15631 16-Dec-15 2015_12 viable FBgn0261553 CG42671 http://flybase.net/reports/FBgn0261553.html "FBgn0036149, FBgn0085269" protein_coding_gene "CG18490, CG34240" CG42671 16-Dec-15 2015_12 FBgn0065507 l(2)SH1185 lethal (2) SH1185 http://flybase.net/reports/FBgn0065507.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040993 CG17325 http://flybase.net/reports/FBgn0040993.html FBgn0061387 protein_coding_gene "BcDNA:RH02271, Dromel_CG17325_FBtr0081102_mORF" CG17325 16-Dec-15 2015_12 FBgn0263314 CG43400 http://flybase.net/reports/FBgn0263314.html protein_coding_gene lincRNA.75 CG43400 16-Dec-15 2015_12 FBgn0030395 Mks1 "Meckel syndrome, type 1 homologue" http://flybase.net/reports/FBgn0030395.html protein_coding_gene 0090175=regulation of establishment of planar polarity 0035869=ciliary transition zone "dMks1, CG15730" IPR010796=B9 domain CG15730 16-Dec-15 2015_12 ENSDARG00000059657(mks1) ENSXETG00000010339(TGas092g16.1) ENSMUSG00000034121(Mks1) ENSG00000011143(MKS1) "viable,planar polarity defective,visible" "ommatidium,wing hair,supernumerary,wing blade" FBgn0053094 Synd Syndapin http://flybase.net/reports/FBgn0053094.html FBgn0038831 protein_coding_gene "0005515=protein binding, 0008289=lipid binding, 0005543=phospholipid binding" "0007053=spindle assembly involved in male meiosis, 0007269=neurotransmitter secretion, 0048488=synaptic vesicle endocytosis, 0061024=membrane organization, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0007112=male meiosis cytokinesis, 0036090=cleavage furrow ingression, 0000281=mitotic cytokinesis" "0045211=postsynaptic membrane, 0030496=midbody, 0071212=subsynaptic reticulum, 0005886=plasma membrane, 0032154=cleavage furrow" "syndapin, synd, CG33094, CG15694, D-Synd" "IPR001060=FCH domain, IPR031160=F-BAR domain, IPR001452=SH3 domain" CG33094 16-Dec-15 2015_12 "ENSDARG00000042128(pacsin1b),ENSDARG00000032865(pacsin1a),ENSDARG00000039300(pacsin2)" WBGene00018467(sdpn-1) "ENSXETG00000003264(pacsin2),ENSXETG00000012375(PACSIN1)" "ENSMUSG00000016664(Pacsin2),ENSMUSG00000040276(Pacsin1),ENSMUSG00000027257(Pacsin3)" "ENSG00000100266(PACSIN2),ENSG00000124507(PACSIN1),ENSG00000165912(PACSIN3)" "lethal - all die before end of pupal stage,some die during pupal stage,viable,majority die during third instar larval stage,cytokinesis defective,meiotic cell cycle defective,body color defective" "subsynaptic reticulum | third instar larval stageMef2.PR,postsynaptic membrane | third instar larval stageMef2.PR,subsynaptic reticulum | third instar larval stagetub.PU,onion stage spermatid,spermatocyte,spindle midzoneBSC43),contractile ringBSC43),cleavage furrowBSC43),meiotic spindleBSC43),mesothoracic tergum" FBgn0259403 C747 http://flybase.net/reports/FBgn0259403.html gene 16-Dec-15 2015_12 visible wing vein FBgn0060582 l(3)S094615b lethal (3) S094615b http://flybase.net/reports/FBgn0060582.html gene 0946/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0083236 EP364 EP364 http://flybase.net/reports/FBgn0083236.html gene 16-Dec-15 2015_12 FBgn0259998 CG17571 http://flybase.net/reports/FBgn0259998.html "FBgn0032947, FBgn0046673" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "38C.22, SP83, anon-38C.22" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG17571 16-Dec-15 2015_12 "ENSDARG00000039728(ctrb1),ENSDARG00000018367(zgc:136461),ENSDARG00000039730(zgc:112160),ENSDARG00000068680(ctrl),ENSDARG00000010378(zgc:171592)" DRSC01768 K 0.016076789 -0.063012137 -0.420297006 -0.048181006 -0.242862419 1.550058018 FBgn0033000 CG14464 http://flybase.net/reports/FBgn0033000.html "FBan0014464, FBgn0058285, FBgn0063147" protein_coding_gene "BcDNA:LD29015, CG40285" "IPR029264=ARF7 effector protein, C-terminal" CG14464 16-Dec-15 2015_12 ENSMUSG00000073568(Gm949) FBgn0022365 Pt-7A Adult protein-7A http://flybase.net/reports/FBgn0022365.html gene 16-Dec-15 2015_12 FBgn0039284 CG13652 http://flybase.net/reports/FBgn0039284.html protein_coding_gene 16-Dec-15 2015_12 "viable,visible" "tormogen cell,mesothoracic tergum" FBgn0060654 l(3)S083005b lethal (3) S083005b http://flybase.net/reports/FBgn0060654.html gene 0830/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0260059 2L1749 http://flybase.net/reports/FBgn0260059.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0043573 S(faf)244 S(faf)244 http://flybase.net/reports/FBgn0043573.html gene 16-Dec-15 2015_12 FBgn0033283 CG11635 http://flybase.net/reports/FBgn0033283.html protein_coding_gene "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG11635 16-Dec-15 2015_12 FBgn0266048 CR44813 http://flybase.net/reports/FBgn0266048.html non_protein_coding_gene lincRNA.390 CR44813 16-Dec-15 2015_12 FBgn0030976 CG7378 http://flybase.net/reports/FBgn0030976.html FBgn0063661 protein_coding_gene "0008138=protein tyrosine/serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" 0006470=protein dephosphorylation "MKP-like, BcDNA:RH25447" "IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR020405=Atypical dual specificity phosphatase, subfamily A, IPR000387=Tyrosine specific protein phosphatases domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR024950=Dual specificity phosphatase, IPR020422=Dual specificity protein phosphatase domain, IPR020417=Atypical dual specificity phosphatase" CG7378 16-Dec-15 2015_12 ENSDARG00000061498(zgc:172281) "ENSXETG00000026435(DUSP13),ENSXETG00000020598(DUPD1),ENSXETG00000025288(DUSP26)" "ENSMUSG00000063821(Dupd1),ENSMUSG00000021768(Dusp13),ENSMUSG00000039661(Dusp26),ENSMUSG00000079337" "ENSG00000079393(DUSP13),ENSG00000188716(DUPD1),ENSG00000133878(DUSP26)" viable FBgn0002050 l(2)37Fc lethal (2) 37Fc http://flybase.net/reports/FBgn0002050.html gene l(2)E42 16-Dec-15 2015_12 lethal FBgn0021834 l(2)k15817 lethal (2) k15817 http://flybase.net/reports/FBgn0021834.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065526 l(2)SH1118 lethal (2) SH1118 http://flybase.net/reports/FBgn0065526.html gene l(2)SH2 1118 16-Dec-15 2015_12 "lethal,recessive" FBgn0259585 B2030 http://flybase.net/reports/FBgn0259585.html gene 16-Dec-15 2015_12 visible metathoracic leg FBgn0034139 CG4927 http://flybase.net/reports/FBgn0034139.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP42 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG4927 16-Dec-15 2015_12 "ENSXETG00000016792(plat),ENSXETG00000007245(F12),ENSXETG00000005495(HGFAC),ENSXETG00000018616(HABP2),ENSXETG00000010002(),ENSXETG00000004035(PRSS12)" "ENSMUSG00000025075(Habp2),ENSMUSG00000029102(Hgfac),ENSMUSG00000031538(Plat),ENSMUSG00000021822(Plau),ENSMUSG00000021492(F12),ENSMUSG00000027978(Prss12)" "viable,fertile" DRSC06903 I 1.700280649 -0.04912185 -1.071771863 -0.039939986 0.846974055 -0.144782249 FBgn0038943 CG5391 http://flybase.net/reports/FBgn0038943.html protein_coding_gene CG5391 16-Dec-15 2015_12 viable FBgn0000002 5SrRNA 5S ribosomal RNA http://flybase.net/reports/FBgn0000002.html FBgn0010528 rRNA_gene 0022625=cytosolic large ribosomal subunit "rRNA, 5S RNA, 2S rRNA, 5S, 5SRNA, 5SrDNA, 5S-rDNA, 5S rDNA, l(2)03068, RNA X, PZ03068, Dm5S, 5S_DM, 5S rRNA" 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0261458 capt capulet http://flybase.net/reports/FBgn0261458.html "FBgn0028388, FBgn0010632, FBgn0022262, FBgn0027062, FBgn0031311, FBgn0053979, FBtr0077983, FBpp0077648, FBtr0077984, FBpp0077649, FBgn0086304" protein_coding_gene "0008179=adenylate cyclase binding, 0003779=actin binding" "0008407=chaeta morphogenesis, 0008360=regulation of cell shape, 0048749=compound eye development, 0042052=rhabdomere development, 0008103=oocyte microtubule cytoskeleton polarization, 0000902=cell morphogenesis, 0046716=muscle cell cellular homeostasis, 0048477=oogenesis, 0048190=wing disc dorsal/ventral pattern formation, 0008154=actin polymerization or depolymerization, 0072499=photoreceptor cell axon guidance, 0007015=actin filament organization" 0005737=cytoplasm "CG5074, Cyclase Associated Protein Capulet, cap, BcDNA:LD24380, acu, punctate, Cyclase-associated protein, capping protein, punc, CG5061, cyclase-associated protein, Capulet, Capt, CG33979, CAP, Dcap, Adenylyl cyclase-associated protein, act up, Cap, l(2)06955, Act up, Acap" "IPR028417=CAP, conserved site, C-terminal, IPR016098=Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal, IPR013912=Adenylate cyclase-associated CAP, C-terminal, IPR003124=WH2 domain, IPR017901=C-CAP/cofactor C-like domain, IPR028419=Adenylyl cyclase-associated protein CAP, fungal type, IPR001837=Adenylate cyclase-associated CAP, IPR006599=CARP motif, IPR013992=Adenylate cyclase-associated CAP, N-terminal" CG33979 16-Dec-15 2015_12 ENSDARG00000016350(cap1) YNL138W(SRV2) WBGene00000294(cas-1) "ENSXETG00000001184(cap1),ENSXETG00000014191(CAP2)" "ENSMUSG00000028656(Cap1),ENSMUSG00000021373(Cap2)" "ENSG00000131236(CAP1),ENSG00000112186(CAP2)" FBgn0050439 CG30439 http://flybase.net/reports/FBgn0050439.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053504 snRNA:U7 small nuclear RNA U7 http://flybase.net/reports/FBgn0053504.html FBgn0067333 snRNA_gene "0003729=mRNA binding, 0003730=mRNA 3'-UTR binding" "0006398=histone mRNA 3'-end processing, 0008334=histone mRNA metabolic process, 0048599=oocyte development" "0005683=U7 snRNP, 0071254=cytoplasmic U snRNP body, 0016604=nuclear body, 0035363=histone locus body" "63E-F U7, U7 snRNA, U7snRNA, CR33504, U7" CR33504 16-Dec-15 2015_12 "male sterile,recessive,female sterile,viable" FBgn0065252 l(2)SH2114 lethal (2) SH2114 http://flybase.net/reports/FBgn0065252.html gene l(2)SH2 2114 16-Dec-15 2015_12 "lethal,recessive" FBgn0063915 McClintock\pol pol http://flybase.net/reports/FBgn0063915.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0004111 opa-e opa repeat http://flybase.net/reports/FBgn0004111.html repeat_region "M, strep repetitive sequence, opa, CAX repeat, M-repeat, opa repeat, strep, CAX, M repeat" 16-Dec-15 2015_12 FBgn0016678 Mab13G5 Monoclonal antibody 13G5 http://flybase.net/reports/FBgn0016678.html gene 16-Dec-15 2015_12 FBgn0046121 E(To)4 E(To)4 http://flybase.net/reports/FBgn0046121.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036958 CG17233 http://flybase.net/reports/FBgn0036958.html FBgn0036957 protein_coding_gene CG6918 IPR025451=Domain of unknown function DUF4211 CG17233 16-Dec-15 2015_12 WBGene00001325(eor-2) ENSXETG00000026639(QSER1) ENSMUSG00000074994(Qser1) "ENSG00000060749(QSER1),ENSG00000126464(PRR12)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266308 CR44973 http://flybase.net/reports/FBgn0266308.html non_protein_coding_gene CR44973 16-Dec-15 2015_12 FBgn0085319 CG34290 http://flybase.net/reports/FBgn0085319.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG34290 16-Dec-15 2015_12 FBgn0038603 PKD Protein Kinase D http://flybase.net/reports/FBgn0038603.html protein_coding_gene "0019992=diacylglycerol binding, 0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004697=protein kinase C activity" "0035556=intracellular signal transduction, 0006468=protein phosphorylation" 0005737=cytoplasm "150131_at, dPKD, PKCm, CG7125, protein kinase D" "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR011009=Protein kinase-like domain, IPR001849=Pleckstrin homology domain, IPR015727=Protein kinase C mu-related, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR020454=Diacylglycerol/phorbol-ester binding, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG7125 16-Dec-15 2015_12 WBGene00012019(dkf-2) ENSXETG00000011427() "ENSMUSG00000024070(Prkd3),ENSMUSG00000002688(Prkd1),ENSMUSG00000041187(Prkd2)" "ENSG00000184304(PRKD1),ENSG00000115825(PRKD3),ENSG00000105287(PRKD2)" viable FBgn0005512 l(2)25Bg lethal (2) 25Bg http://flybase.net/reports/FBgn0005512.html gene "l(2)jf16, jf16" 16-Dec-15 2015_12 lethal FBgn0024884 l(2)03055 lethal (2) 03055 http://flybase.net/reports/FBgn0024884.html gene 3055 16-Dec-15 2015_12 "lethal,recessive" FBgn0015485 l(2)46Ci lethal (2) 46Ci http://flybase.net/reports/FBgn0015485.html FBgn0019715 gene "M, l(2)46CFm, 17.5, Complementation group M, unnamed" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033815 CG4676 http://flybase.net/reports/FBgn0033815.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG4676 16-Dec-15 2015_12 ENSDARG00000036364(zdhhc24) YOL003C(PFA4) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) viable FBgn0027546 CG4766 http://flybase.net/reports/FBgn0027546.html protein_coding_gene "gh11415, BcDNA:GH11415" "IPR024810=Mab-21 domain, IPR020950=Protein male abnormal 21-related" CG4766 16-Dec-15 2015_12 "ENSDARG00000055089(mab21l1),ENSDARG00000015266(mab21l2)" WBGene00003112(mab-21) ENSXETG00000017124(MAB21L1) "ENSMUSG00000056947(Mab21l1),ENSMUSG00000057777(Mab21l2)" "ENSG00000181541(MAB21L2),ENSG00000180660(MAB21L1)" viable FBgn0014271 l(2)k09619 lethal (2) k09619 http://flybase.net/reports/FBgn0014271.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0260057 2L3937 http://flybase.net/reports/FBgn0260057.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0045486 Gr36b Gustatory receptor 36b http://flybase.net/reports/FBgn0045486.html "FBgn0032628, FBgn0045489, FBgn0051744" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "gustatory receptor 36b, Gr36B2, CG15137, Gustatory receptor 36B2, CG31744, Gr36B.2, GR36b" IPR013604=7TM chemoreceptor CG31744 16-Dec-15 2015_12 viable FBgn0001187 Hex-C Hexokinase C http://flybase.net/reports/FBgn0001187.html FBgn0034003 protein_coding_gene "0004340=glucokinase activity, 0005536=glucose binding, 0019158=mannokinase activity, 0004396=hexokinase activity, 0008865=fructokinase activity, 0005524=ATP binding" "0006096=glycolytic process, 0001678=cellular glucose homeostasis, 0046835=carbohydrate phosphorylation, 0046331=lateral inhibition" 0005829=cytosol "HexokinaseC, Hex-c, Fructokinase, CT22069, hexokinase-C, hexokinase, HEX, HK, HexC, HEX-C, Hex-3, hexokinase C, HK-C, Hex, Hexokinase, HEX-3, CG8094, Hexokinase-3, Hk, hexose kinase, Fk, DM2" "IPR022672=Hexokinase, N-terminal, IPR022673=Hexokinase, C-terminal, IPR001312=Hexokinase" CG8094 16-Dec-15 2015_12 "ENSDARG00000026964(hk2),ENSDARG00000039452(hk1),ENSDARG00000038703(hkdc1),ENSDARG00000068006(gck)" "YFR053C(HXK1),YGL253W(HXK2)" WBGene00008780(F14B4.2) "ENSXETG00000019003(GCK),ENSXETG00000019639()" ENSMUSG00000041798(Gck) "ENSG00000106633(GCK),ENSG00000159399(HK2),ENSG00000156515(HK1),ENSG00000156510(HKDC1)" "electrophoretic variant,viable,visible" "chaeta,trichogen cell,supernumerary,tormogen cell" FBgn0039625 ë_4GalNAcTB ë_4GalNAcTB http://flybase.net/reports/FBgn0039625.html protein_coding_gene "0033207=beta-1,4-N-acetylgalactosaminyltransferase activity, 0033842=N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity, 0008376=acetylgalactosaminyltransferase activity" "0005975=carbohydrate metabolic process, 0006044=N-acetylglucosamine metabolic process, 0006688=glycosphingolipid biosynthetic process, 0009247=glycolipid biosynthetic process" 0005794=Golgi apparatus "CG14517, beta4GalTB, dbeta4GalTB, beta4GalNAcTB" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR027995=Galactosyltransferase, N-terminal, IPR003859=Beta-1,4-galactosyltransferase, IPR027791=Galactosyltransferase, C-terminal" CG14517 16-Dec-15 2015_12 "viable,fertile" FBgn0070011 BG01296 BG01296 http://flybase.net/reports/FBgn0070011.html gene 16-Dec-15 2015_12 stress response defective FBgn0037688 CG9356 http://flybase.net/reports/FBgn0037688.html protein_coding_gene "0043001=Golgi to plasma membrane protein transport, 0007030=Golgi organization" IPR027095=Golgin-45 CG9356 16-Dec-15 2015_12 ENSXETG00000002419(blzf1) FBgn0029167 Hml Hemolectin http://flybase.net/reports/FBgn0029167.html protein_coding_gene "0008061=chitin binding, 0030246=carbohydrate binding, 0042803=protein homodimerization activity" "0007599=hemostasis, 0035006=melanization defense response, 0042060=wound healing, 0042381=hemolymph coagulation, 0006030=chitin metabolic process" 0005576=extracellular region "hml, hemolectin, d-hml, CT21553, CG7002" "IPR000742=EGF-like domain, IPR000421=Coagulation factor 5/8 C-terminal domain, IPR001007=VWFC domain, IPR012111=Hemolectin/hemocytin, IPR013032=EGF-like, conserved site, IPR000436=Sushi/SCR/CCP domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR002557=Chitin binding domain, IPR008979=Galactose-binding domain-like, IPR002919=Trypsin Inhibitor-like, cysteine rich domain, IPR006207=Cystine knot, C-terminal, IPR001846=von Willebrand factor, type D domain, IPR014853=Uncharacterised domain, cysteine-rich" CG7002 16-Dec-15 2015_12 "ENSDARG00000058556,ENSDARG00000060911,ENSDARG00000070331,ENSDARG00000060302" ENSXETG00000023591(VWF) ENSMUSG00000001930(Vwf) "ENSG00000117983(MUC5B),ENSG00000198788(MUC2)" " embryonic stage | stage 17 , larval stage | first instar , larval stage " " embryonic hemocyte

, larval hemocyte

, organism

, crystal cell | subset

, plasmatocyte | subset

" "viable,fertile,immune response defective" FBgn0028385 cod capodimonte http://flybase.net/reports/FBgn0028385.html gene 16-Dec-15 2015_12 FBgn0004068 fs(2)mel2 female sterile (2) maternal effect lethal 2 http://flybase.net/reports/FBgn0004068.html gene mel 2 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,embryo,maternal effect" FBgn0267132 CR45572 http://flybase.net/reports/FBgn0267132.html non_protein_coding_gene CR45572 16-Dec-15 2015_12 FBgn0040050 CG17403 http://flybase.net/reports/FBgn0040050.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065757 l(2)SH0486 lethal (2) SH0486 http://flybase.net/reports/FBgn0065757.html gene l(2)SH2 0486 16-Dec-15 2015_12 "lethal,recessive" FBgn0275436 Aats-phe-m mitochondrial phenylalanyl-tRNA synthetase http://flybase.net/reports/FBgn0275436.html "FBgn0027628, FBgn0028548, FBgn0020766" protein_coding_gene "0000287=magnesium ion binding, 0000049=tRNA binding, 0004826=phenylalanine-tRNA ligase activity, 0005524=ATP binding" "0006432=phenylalanyl-tRNA aminoacylation, 0008033=tRNA processing" 0005739=mitochondrion "mtPheRS, Aats-phe, unnamed, Phenylalanyl-tRNA synthetase, Pts, CG13348, PheRS, FRS" "IPR006195=Aminoacyl-tRNA synthetase, class II, IPR005121=Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding, IPR002319=Phenylalanyl-tRNA synthetase, IPR004530=Phenylalanyl-tRNA synthetase, class IIc, mitochondrial" CG13348 16-Dec-15 2015_12 ENSDARG00000045455 YPR047W(MSF1) WBGene00013361(fars-2) ENSMUSG00000021420(Fars2) ENSG00000145982(FARS2) "viable,visible,decreased cell size,cell autonomous,somatic clone" "trichogen cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0032285 CG17108 http://flybase.net/reports/FBgn0032285.html FBgn0043811 protein_coding_gene "CT33647, gh23489, BEST:GH23489" CG17108 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0029769 frma fra mauro http://flybase.net/reports/FBgn0029769.html FBgn0043827 protein_coding_gene 0004222=metalloendopeptidase activity "0045434=negative regulation of female receptivity, post-mating, 0006508=proteolysis" "BEST:GH09377, Dmel_CG3239, CG3239" "IPR008753=Peptidase M13, N-terminal domain, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13" CG3239 16-Dec-15 2015_12 "mating behavior defective,female limited,female semi-fertile" FBgn0039726 eIF2B-ë± eIF2B-ë± http://flybase.net/reports/FBgn0039726.html protein_coding_gene "0046523=S-methyl-5-thioribose-1-phosphate isomerase activity, 0005085=guanyl-nucleotide exchange factor activity, 0003743=translation initiation factor activity, 0030234=enzyme regulator activity" "0006446=regulation of translational initiation, 0019509=L-methionine biosynthetic process from methylthioadenosine, 0006413=translational initiation, 0046331=lateral inhibition" "0005851=eukaryotic translation initiation factor 2B complex, 0005737=cytoplasm, 0005829=cytosol" "CG7883, DeIF2Balpha, eIF2B-alpha" IPR000649=Initiation factor 2B-related CG7883 16-Dec-15 2015_12 "ENSDARG00000067561,ENSDARG00000009913(LOC100151592)" YKR026C(GCN3) WBGene00014221(ZK1098.4) ENSXETG00000005830(eif2b1) ENSMUSG00000029388(Eif2b1) ENSG00000111361(EIF2B1) "viable,visible" "chaeta,trichogen cell" FBgn0050287 CG30287 http://flybase.net/reports/FBgn0050287.html FBgn0034635 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH37, Dmel_CG30287, CG10450, SP37" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG30287 16-Dec-15 2015_12 FBgn0029863 CG3823 http://flybase.net/reports/FBgn0029863.html protein_coding_gene "0008431=vitamin E binding, 0005215=transporter activity" 0006810=transport 0005622=intracellular "IPR011074=CRAL/TRIO, N-terminal domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251=CRAL-TRIO lipid binding domain" CG3823 16-Dec-15 2015_12 "viable,fertile" FBgn0022745 anon-J1b anon-J1b http://flybase.net/reports/FBgn0022745.html gene J1 16-Dec-15 2015_12 FBgn0040004 CG12552 http://flybase.net/reports/FBgn0040004.html FBan0012552 protein_coding_gene 16-Dec-15 2015_12 FBgn0263995 cpo couch potato http://flybase.net/reports/FBgn0263995.html "FBgn0000363, FBgn0011025, FBgn0011358, FBgn0011368, FBgn0011405, FBgn0011416, FBgn0011503, FBgn0038560, FBgn0038561, FBgn0038562, FBgn0051243, FBgn0063288, FBgn0066121, FBgn0259934" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "0022611=dormancy process, 0007422=peripheral nervous system development, 0007268=synaptic transmission, 0042048=olfactory behavior, 0035206=regulation of hemocyte proliferation" 0005634=nucleus "l(3)01432, Cpo, CG31243, CG18435, Couch potato, CG42457, 5339, l(3)j4A1, 3603, cg18435, l(3)j9B3, 1824, unnamed, 6015, E(sda)N, Line N, CPO, BcDNA:AT31405, ORE-17, l(3)j4D4, l(3)s2336, CG43738, l(3)6015, CG18434, l(3)rJ553, CG12349, l(3)j7E2" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG43738 16-Dec-15 2015_12 "YNL197C(WHI3),YDL224C(WHI4)" embryonic stage " neuron &&of chordotonal organ

, embryonic peripheral nervous system

" embryonic stage " central nervous system

{ 0 AS-C- } , peripheral nervous system

, glial cell

, neuron chordotonal organ

{ 0 AS-C- } , sensory organ mother cell

{ - da* } , posterior spiracle

{ - AS-C- } , central nervous system

{ $ da* } , peripheral nervous system

{ 0 AS-C- } , peripheral nervous system

{ 0 da* } , embryonic central nervous system

, neuron

, embryonic/larval midgut

, midgut

{ 0 da* } , glial cell

{ 0 AS-C- } , midgut

" DRSC13265 I 1.374389261 1.553335766 -0.049318037 -0.250038696 -0.012647936 -0.182963195 FBgn0041236 Gr59d Gustatory receptor 59d http://flybase.net/reports/FBgn0041236.html "FBgn0034823, FBgn0050330" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "59D.1, 59D1, GR59D.1, Gustatory receptor 59D.1, CG30330, CG13543, GR59d, Gr59D1" IPR013604=7TM chemoreceptor CG30330 16-Dec-15 2015_12 viable FBgn0032800 CG10137 http://flybase.net/reports/FBgn0032800.html protein_coding_gene "0016596=thienylcyclohexylpiperidine binding, 0016594=glycine binding, 0016595=glutamate binding" IPR008979=Galactose-binding domain-like CG10137 16-Dec-15 2015_12 ENSDARG00000060361(LOC795993) ENSMUSG00000039523(BC046331) ENSG00000116198(CEP104) viable FBgn0051866 Ada1-2 transcriptional Adaptor 1-2 http://flybase.net/reports/FBgn0051866.html protein_coding_gene "0004402=histone acetyltransferase activity, 0003713=transcription coactivator activity" "0006366=transcription from RNA polymerase II promoter, 0016573=histone acetylation, 0043966=histone H3 acetylation" "0000124=SAGA complex, 0005634=nucleus" "Ada1, Ada1-2, ada1-2, CG31866" IPR024738=Transcriptional coactivator Hfi1/Transcriptional adapter 1 CG31866 16-Dec-15 2015_12 ENSXETG00000000526(tada1l) ENSMUSG00000026563(Tada1) ENSG00000152382(TADA1) FBgn0013696 mt:tRNA:I mitochondrial isoleucine tRNA http://flybase.net/reports/FBgn0013696.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "CR34060, tRNA[Ile], mtdbD00006292" CR34060 16-Dec-15 2015_12 FBgn0039893 CG13301 http://flybase.net/reports/FBgn0039893.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262882 CG43237 http://flybase.net/reports/FBgn0262882.html protein_coding_gene lincRNA.333 CG43237 16-Dec-15 2015_12 FBgn0020806 ms(2)C32 ms(2)C32 http://flybase.net/reports/FBgn0020806.html gene 2-C32 16-Dec-15 2015_12 "male sterile,recessive,chemical sensitive" FBgn0266637 CR45144 http://flybase.net/reports/FBgn0266637.html non_protein_coding_gene CR45144 16-Dec-15 2015_12 FBgn0010948 l(3)10621 lethal (3) 10621 http://flybase.net/reports/FBgn0010948.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0005502 slf schlaff http://flybase.net/reports/FBgn0005502.html "FBgn0001912, FBgn0003422" gene 0001700=embryonic development via the syncytial blastoderm l(2)25Aa 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,cephalopharyngeal skeleton,embryo,posterior,anterior" FBgn0043899 gsb::Mmus\Pax3 Pax3 http://flybase.net/reports/FBgn0043899.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0067072 Mns Microtubule nucleation suppressor http://flybase.net/reports/FBgn0067072.html gene "Minus, MINUS" 16-Dec-15 2015_12 FBgn0028693 Rpn12 Regulatory particle non-ATPase 12 http://flybase.net/reports/FBgn0028693.html protein_coding_gene "0006511=ubiquitin-dependent protein catabolic process, 0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0022008=neurogenesis, 0008283=cell proliferation, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0000502=proteasome complex, 0008541=proteasome regulatory particle, lid subcomplex, 0005838=proteasome regulatory particle" "dRpn12, p30, Rpn12, CG4157, S14" IPR006746=26S proteasome non-ATPase regulatory subunit Rpn12 CG4157 16-Dec-15 2015_12 ENSDARG00000020454(zgc:86762) YFR052W(RPN12) WBGene00004468(rpn-12) ENSXETG00000002818(Q6DEV4_XENTR) ENSMUSG00000030591(Psmd8) ENSG00000099341(PSMD8) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC11275 IEK -2.898831702 -3.190066818 -2.817372184 -1.933076306 1.385172297 -2.642958187 FBgn0011045 l(1)Stark-d lethal (1) of Stark d http://flybase.net/reports/FBgn0011045.html FBgn0010212 gene "lethal (1) Sd, l(1)Sd" 16-Dec-15 2015_12 lethal FBgn0029955 CG15478 http://flybase.net/reports/FBgn0029955.html protein_coding_gene CG15478 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "heart primordium,chaeta,supernumerary" FBgn0051648 CG31648 http://flybase.net/reports/FBgn0051648.html FBgn0031712 protein_coding_gene 0005507=copper ion binding 0008535=respiratory chain complex IV assembly 0005743=mitochondrial inner membrane "CG6922, Complex IV assembly protein COX11, COXZ, Cytochrome c oxidase assembly protein COX11" "IPR007533=Cytochrome c oxidase assembly protein CtaG/Cox11, IPR023471=Cytochrome c oxidase assembly protein CtaG/Cox11, domain" CG31648 16-Dec-15 2015_12 ENSDARG00000061004(zgc:162286) YPL132W(COX11) WBGene00010437(JC8.5) ENSXETG00000023638(COX11) ENSMUSG00000020544(Cox11) ENSG00000166260(COX11) "viable,visible" trichogen cell FBgn0067040 W10 W10 http://flybase.net/reports/FBgn0067040.html gene 16-Dec-15 2015_12 "lethal,viable" FBgn0023096 btv beethoven http://flybase.net/reports/FBgn0023096.html FBgn0032657 protein_coding_gene "0005524=ATP binding, 0003774=motor activity, 0016887=ATPase activity, 0003777=microtubule motor activity, 0042623=ATPase activity, coupled" "0007628=adult walking behavior, 0008049=male courtship behavior, 0035721=intraciliary retrograde transport, 0007018=microtubule-based movement, 0007605=sensory perception of sound, 0045433=male courtship behavior, veined wing generated song production, 0031223=auditory behavior" "0005930=axoneme, 0005868=cytoplasmic dynein complex, 0005875=microtubule associated complex" "Dynein heavy chain 36D, DHC, CG15148, DHC36D, Dhc36D, DyneinHC" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013594=Dynein heavy chain, domain-1, IPR004273=Dynein heavy chain domain, IPR026815=Cytoplasmic dynein 2 heavy chain 1, IPR011704=ATPase, dynein-related, AAA domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR003593=AAA+ ATPase domain, IPR026983=Dynein heavy chain, IPR013602=Dynein heavy chain, domain-2" CG15148 16-Dec-15 2015_12 WBGene00000485(che-3) ENSMUSG00000047193(Dync2h1) "thermotaxis behavior defective,touch sensitivity defective,locomotor behavior defective,auditory perception defective,neuroanatomy defective,viable,smell perception defective,courtship behavior defective,male,male fertile,song defective,recessive,behavior defective" "abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidium,arista,mechanosensory sensory organ,wing,adult antennal nerve" FBgn0265860 CR44649 http://flybase.net/reports/FBgn0265860.html non_protein_coding_gene CR44649 16-Dec-15 2015_12 FBgn0031184 CG14615 http://flybase.net/reports/FBgn0031184.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR016181=Acyl-CoA N-acyltransferase, IPR013653=FR47-like" CG14615 16-Dec-15 2015_12 viable FBgn0001018 fs(3)A9 female sterile (3) A9 http://flybase.net/reports/FBgn0001018.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0016981 snRNA:K2b small nuclear RNA K2b http://flybase.net/reports/FBgn0016981.html snRNA_gene K2b 16-Dec-15 2015_12 FBgn0005093 fs(2)OWc5 female sterile (2) OWc5 http://flybase.net/reports/FBgn0005093.html gene 16-Dec-15 2015_12 FBgn0032233 dpr19 defective proboscis extension response 19 http://flybase.net/reports/FBgn0032233.html FBgn0063091 protein_coding_gene 0007606=sensory perception of chemical stimulus "CG13140, Dpr19, BcDNA:LP09705, Dpr-19, dpr19" "IPR007110=Immunoglobulin-like domain, IPR013106=Immunoglobulin V-set domain, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG13140 16-Dec-15 2015_12 WBGene00006985(zig-8) ENSMUSG00000048534(Amica1) "ENSG00000105767(CADM4),ENSG00000182985(CADM1),ENSG00000175161(CADM2),ENSG00000162706(CADM3)" viable FBgn0050154 CG30154 http://flybase.net/reports/FBgn0050154.html protein_coding_gene CG30154 16-Dec-15 2015_12 viable FBgn0039405 CG14550 http://flybase.net/reports/FBgn0039405.html FBgn0063183 protein_coding_gene "BcDNA:GM30016, Dromel_CG14550_FBtr0084974_mORF" IPR013717=PIG-P CG14550 16-Dec-15 2015_12 ENSDARG00000038805(pigp) ENSXETG00000018803(PIGP) ENSG00000185808(PIGP) viable FBgn0085697 CG41568 http://flybase.net/reports/FBgn0085697.html FBan0041568 protein_coding_gene 16-Dec-15 2015_12 FBgn0262331 mir-999 mir-999 stem loop http://flybase.net/reports/FBgn0262331.html miRNA_gene "miR999, dme-mir-999, miR-999, CR43038, dme-miR-999" CR43038 16-Dec-15 2015_12 "lethal,visible,lethal - all die before end of P-stage,some die during pharate adult stage" wing FBgn0004040 yea6 yeast 6 http://flybase.net/reports/FBgn0004040.html gene 16-Dec-15 2015_12 FBgn0065420 l(2)SH1525 lethal (2) SH1525 http://flybase.net/reports/FBgn0065420.html gene l(2)SH2 1525 16-Dec-15 2015_12 "lethal,recessive" FBgn0051343 CG31343 http://flybase.net/reports/FBgn0051343.html "FBgn0038898, FBgn0043816, FBgn0044540" protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "anon-WO0140519.86, CG5839, BEST:GH20248" "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain" CG31343 16-Dec-15 2015_12 viable FBgn0032732 CG15168 http://flybase.net/reports/FBgn0032732.html FBgn0047175 protein_coding_gene BcDNA:RE09053 IPR018937=Magnesium transporter CG15168 16-Dec-15 2015_12 ENSDARG00000010553(mmgt1) ENSXETG00000024459(tmem32) "ENSMUSG00000061273(Mmgt1),ENSMUSG00000048497(Mmgt2)" ENSG00000169446(MMGT1) "partially lethal - majority die,some die during pupal stage" FBgn0050043 CG30043 http://flybase.net/reports/FBgn0050043.html FBgn0033719 protein_coding_gene CG13161 IPR007484=Peptidase M28 CG30043 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0260313 GSd445 http://flybase.net/reports/FBgn0260313.html gene 16-Dec-15 2015_12 lethal FBgn0031204 CG9562 http://flybase.net/reports/FBgn0031204.html protein_coding_gene "tartan/capricious-like, CT16794" 16-Dec-15 2015_12 FBgn0053727 snmRNA:430:CR33727 snmRNA:430:CR33727 http://flybase.net/reports/FBgn0053727.html non_protein_coding_gene CR33727 CR33727 16-Dec-15 2015_12 FBgn0039299 CG11854 http://flybase.net/reports/FBgn0039299.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG11854 16-Dec-15 2015_12 viable FBgn0065736 l(2)SH0541 lethal (2) SH0541 http://flybase.net/reports/FBgn0065736.html gene l(2)SH2 0541 16-Dec-15 2015_12 "lethal,recessive" FBgn0004994 Cor Corroded eye http://flybase.net/reports/FBgn0004994.html gene 16-Dec-15 2015_12 "visible,dominant" eye FBgn0053669 CG33669 http://flybase.net/reports/FBgn0053669.html FBgn0045422 protein_coding_gene "NEST:bs03a05, bs03a05.y1" CG33669 16-Dec-15 2015_12 FBgn0029115 TO42 TO42 http://flybase.net/reports/FBgn0029115.html gene "0005506=iron ion binding, 0051536=iron-sulfur cluster binding" 0016226=iron-sulfur cluster assembly "unnamed, clot#9754" "IPR014824=Scaffold protein Nfu/NifU, N-terminal, IPR017065=NFU1 iron-sulfur cluster scaffold homologue, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001075=NIF system FeS cluster assembly, NifU, C-terminal" 16-Dec-15 2015_12 FBgn0037402 Vha14-2 Vacuolar H+ ATPase 14kD subunit 2 http://flybase.net/reports/FBgn0037402.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033176=proton-transporting V-type ATPase complex, 0000221=vacuolar proton-transporting V-type ATPase, V1 domain" "CG1076, vha14-2, Vacuolar H[+] ATPase subunit 14-2" "IPR008218=ATPase, V1 complex, subunit F, IPR005772=ATPase, V1 complex, subunit F, eukaryotic" CG1076 16-Dec-15 2015_12 viable FBgn0011215 cash cashews http://flybase.net/reports/FBgn0011215.html gene 0007286=spermatid development cas 16-Dec-15 2015_12 "male sterile,recessive" FBgn0044083 E(rst)H186 E(rst)H186 http://flybase.net/reports/FBgn0044083.html gene 0001745=compound eye morphogenesis H186 16-Dec-15 2015_12 viable eye FBgn0040737 Tango8 Transport and Golgi organization 8 http://flybase.net/reports/FBgn0040737.html protein_coding_gene "0007030=Golgi organization, 0009306=protein secretion" 0005783=endoplasmic reticulum "TANGO8, CG14503" CG14503 16-Dec-15 2015_12 FBgn0267612 CR45950 http://flybase.net/reports/FBgn0267612.html non_protein_coding_gene CR45950 16-Dec-15 2015_12 FBgn0039031 CG17244 http://flybase.net/reports/FBgn0039031.html FBgn0062956 protein_coding_gene 0005125=cytokine activity 0007165=signal transduction BcDNA:RH17470 CG17244 16-Dec-15 2015_12 viable DRSC15206 K 0.463009169 -0.325969033 1.052178418 -0.225560437 -1.608280657 -0.859813274 FBgn0263476 snoRNA:CG32479-b http://flybase.net/reports/FBgn0263476.html snoRNA_gene CR43591 16-Dec-15 2015_12 FBgn0033461 CG12923 http://flybase.net/reports/FBgn0033461.html protein_coding_gene CG12923 16-Dec-15 2015_12 viable FBgn0016842 l(1)N15 lethal (1) N15 http://flybase.net/reports/FBgn0016842.html gene N15 16-Dec-15 2015_12 "lethal,recessive" FBgn0038879 CG17298 http://flybase.net/reports/FBgn0038879.html FBgn0047019 protein_coding_gene "CT35916, BcDNA:RH37844" CG17298 16-Dec-15 2015_12 viable FBgn0038816 Lrrk Leucine-rich repeat kinase http://flybase.net/reports/FBgn0038816.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005525=GTP binding, 0017137=Rab GTPase binding" "0050808=synapse organization, 1900242=regulation of synaptic vesicle endocytosis, 0032418=lysosome localization, 0040011=locomotion, 1901215=negative regulation of neuron death, 0008088=axon cargo transport, 0007264=small GTPase mediated signal transduction, 0018105=peptidyl-serine phosphorylation" "0005765=lysosomal membrane, 0031902=late endosome membrane" "lrrk, CT17358, LRRK2, dLRRK, CG5483, LRRK" "IPR013684=Mitochondrial Rho-like, IPR002110=Ankyrin repeat, IPR020859=Roc domain, IPR020683=Ankyrin repeat-containing domain, IPR017441=Protein kinase, ATP binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR003591=Leucine-rich repeat, typical subtype, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR001611=Leucine-rich repeat" CG5483 16-Dec-15 2015_12 ENSDARG00000007398 WBGene00003068(lrk-1) ENSXETG00000015924() ENSMUSG00000015133(Lrrk1) ENSG00000154237(LRRK1) "viable,neuroanatomy defective,chemical sensitive,locomotor behavior defective,female fertile,reduced,chemical resistant,female sterile,neurophysiology defective,female semi-sterile" "lysosomeCY2,type I bouton,neuromuscular junction,neuromuscular junctionMhc.PW,dopaminergic neuron,adult abdomen,female,dendritic arborizing neuron | third instar larval stage,NMJ bouton,mitochondrion" FBgn0262774 Su(E1)-H http://flybase.net/reports/FBgn0262774.html gene 16-Dec-15 2015_12 FBgn0002900 mus302 mutagen-sensitive 302 http://flybase.net/reports/FBgn0002900.html gene mus(3)302 16-Dec-15 2015_12 "viable,chemical sensitive,recessive,semidominant,radiation sensitive,female fertile,poor,DNA repair defective" FBgn0011047 l(3)AFA17 lethal (3) AFA17 http://flybase.net/reports/FBgn0011047.html FBgn0005200 gene 16-Dec-15 2015_12 lethal FBgn0024492 BITP-15 BITP-15 http://flybase.net/reports/FBgn0024492.html gene 16-Dec-15 2015_12 FBgn0036333 MICAL-like MICAL-like http://flybase.net/reports/FBgn0036333.html protein_coding_gene "0003779=actin binding, 0008270=zinc ion binding, 0017137=Rab GTPase binding" 0032456=endocytic recycling "AAK93415, CG11259" "IPR001715=Calponin homology domain, IPR028563=MICAL-like protein 1, IPR022735=Domain of unknown function DUF3585, IPR001781=Zinc finger, LIM-type" CG11259 16-Dec-15 2015_12 "ENSDARG00000052694(LOC100330729),ENSDARG00000017834(zgc:55983)" ENSXETG00000018105(TGas014p14.1) ENSMUSG00000033039 "ENSG00000164877(MICALL2),ENSG00000100139(MICALL1)" "viable,fertile" FBgn0003663 ta tapered http://flybase.net/reports/FBgn0003663.html gene 0007619=courtship behavior 16-Dec-15 2015_12 "viable,reduced,visible,female fertile,male sterile,dominant,behavior defective,poor,lethal,recessive" "wing,wing vein" FBgn0035022 CG11413 http://flybase.net/reports/FBgn0035022.html FBgn0061382 protein_coding_gene "CT31865, BcDNA:RH33060" CG11413 16-Dec-15 2015_12 "viable,fertile" FBgn0069185 mcl(2)Z0193 mcl(2)Z0193 http://flybase.net/reports/FBgn0069185.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0264297 CG43775 http://flybase.net/reports/FBgn0264297.html FBgn0034979 protein_coding_gene 0005576=extracellular region "CG13569, CG13569-1" "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG43775 16-Dec-15 2015_12 viable FBgn0065802 l(2)SH0404 lethal (2) SH0404 http://flybase.net/reports/FBgn0065802.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003934 snRNA:U5:23D small nuclear RNA U5 at 23DE http://flybase.net/reports/FBgn0003934.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "U5 small nuclear RNA, snRNA[[3]], dU5, CR32999, snRNA4, snRNA:U5, small nuclear RNA U5, U5 snRNA, U5, snRNA:U5:23DE, U5:23D, snRNA3, U5-23D, U5snRNA23DE, U5snRNA, U5 snRNA 23D, K2" CR32999 16-Dec-15 2015_12 FBgn0266072 CR44825 http://flybase.net/reports/FBgn0266072.html non_protein_coding_gene CR44825 16-Dec-15 2015_12 FBgn0065912 l(2)SH0177 lethal (2) SH0177 http://flybase.net/reports/FBgn0065912.html gene l(2)SH2 0177 16-Dec-15 2015_12 "lethal,recessive" FBgn0035715 CG10103 http://flybase.net/reports/FBgn0035715.html protein_coding_gene 0032509=endosome transport via multivesicular body sorting pathway 0005768=endosome "IPR005061=Domain of unknown function DUF292, eukaryotic" CG10103 16-Dec-15 2015_12 ENSDARG00000051888(zgc:55671) YNL265C(IST1) WBGene00010736(K10C8.3) ENSXETG00000023423(KIAA0174) ENSMUSG00000031729(2400003C14Rik) ENSG00000182149(KIAA0174) viable FBgn0265487 mbl http://flybase.net/reports/FBgn0265487.html "FBgn0053197, FBgn0261642, FBgn0010471, FBgn0015514, FBgn0020274, FBgn0022250, FBgn0034208, FBgn0020555, FBgn0070016" protein_coding_gene "0046872=metal ion binding, 0003677=DNA binding, 0003676=nucleic acid binding" "0007476=imaginal disc-derived wing morphogenesis, 0007525=somatic muscle development, 0046716=muscle cell cellular homeostasis, 0007422=peripheral nervous system development, 0001654=eye development, 0001751=compound eye photoreceptor cell differentiation, 0010468=regulation of gene expression, 0007517=muscle organ development, 0045924=regulation of female receptivity, 0006915=apoptotic process, 0042052=rhabdomere development, 0000381=regulation of alternative mRNA splicing, via spliceosome" "0030018=Z disc, 0005634=nucleus, 0031673=H zone, 0005737=cytoplasm, 0048471=perinuclear region of cytoplasm" "mb1, muscleblind, l(2)01038, l(2)k05507, BG01127, Mbl, mm, mbn, chst, unnamed, MUSCLEBLIND, Muscleblind, l(2)k01212, CG14477, n(2)k07110, CG10941, mindmelt, cht, chaste, CG33197" "IPR000571=Zinc finger, CCCH-type" CG33197 16-Dec-15 2015_12 "ENSDARG00000016085(mbnl3),ENSDARG00000018460(mbnl2),ENSDARG00000052978(mbnl1)" WBGene00019347(mbl-1) "ENSXETG00000021655(MBNL1),ENSXETG00000005409(MBNL3)" "ENSMUSG00000027763(Mbnl1),ENSMUSG00000022139(Mbnl2),ENSMUSG00000036109(Mbnl3)" "ENSG00000152601(MBNL1),ENSG00000139793(MBNL2),ENSG00000076770(MBNL3)" larval stage eye disc

larval stage " early ommatidial precursor cluster

, imaginal disc

" FBgn0060740 l(3)S066619b lethal (3) S066619b http://flybase.net/reports/FBgn0060740.html gene 0666/19 16-Dec-15 2015_12 "lethal,recessive" FBgn0034099 CG15708 http://flybase.net/reports/FBgn0034099.html protein_coding_gene 0003677=DNA binding "IPR003656=Zinc finger, BED-type, IPR006629=LPS-induced tumour necrosis factor alpha factor" CG15708 16-Dec-15 2015_12 viable FBgn0262751 Mst77Y-2 Male-specific transcript 77Y 2 http://flybase.net/reports/FBgn0262751.html nuclear_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin 16-Dec-15 2015_12 FBgn0030280 CG11106 http://flybase.net/reports/FBgn0030280.html FBgn0047335 protein_coding_gene BcDNA:AT24116 CG11106 16-Dec-15 2015_12 viable DRSC19381 K 0.412976335 -0.065854499 0.080563275 -0.196760164 1.690240472 0.224836486 FBgn0001725 l(1)ESHS46 lethal (1) ESHS46 http://flybase.net/reports/FBgn0001725.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034939 thoc5 thoc5 http://flybase.net/reports/FBgn0034939.html protein_coding_gene "0007140=male meiosis, 0006406=mRNA export from nucleus" "0005730=nucleolus, 0043234=protein complex, 0000347=THO complex, 0000228=nuclear chromosome" "garm, THOC5, garmcho, CG2980" "IPR019163=THO complex, subunit 5" CG2980 16-Dec-15 2015_12 "ENSDARG00000038290(thoc5),ENSDARG00000069670" WBGene00021311(Y32H12A.2) ENSXETG00000016419(TEgg015p03.1) ENSMUSG00000034274(Thoc5) ENSG00000100296(THOC5) "male sterile,recessive,female fertile,viable" "nucleolus,condensed nuclear chromosome,spermatid" FBgn0034478 CG10822 http://flybase.net/reports/FBgn0034478.html protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex IPR004942=Roadblock/LAMTOR2 domain CG10822 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0086284 GS8172 http://flybase.net/reports/FBgn0086284.html gene 8172 16-Dec-15 2015_12 FBgn0023216 Parg Poly(ADP-ribose) glycohydrolase http://flybase.net/reports/FBgn0023216.html protein_coding_gene 0004649=poly(ADP-ribose) glycohydrolase activity "0009408=response to heat, 0006909=phagocytosis, 0006342=chromatin silencing, 0030576=Cajal body organization, 0036099=female germ-line stem cell maintenance, 0051457=maintenance of protein location in nucleus, 0035065=regulation of histone acetylation, 0043484=regulation of RNA splicing, 0005975=carbohydrate metabolic process" "0005634=nucleus, 0005654=nucleoplasm" "HD10914, Poly(ADPribose) glyco-hydrolase, CG2864, parg, Poly(ADP-ribose) Glycohydrolase, EG:114E2.1, PARG, poly(ADP-ribose) glycohydrolase, Poly(ADP-ribose)glycohydrolase" IPR007724=Poly(ADP-ribose) glycohydrolase CG2864 16-Dec-15 2015_12 ENSDARG00000068420 "WBGene00004052(pme-4),WBGene00004051(pme-3)" ENSMUSG00000021911(Parg) ENSG00000214982 "visible,partially lethal - majority die,cold sensitive,short lived,sterile,neuroanatomy defective,melanotic mass phenotype,lethal,partially,heat stress response defective,viable" "dorsocentral bristle,scutellar bristle,ectopic,microchaeta,wing,mesothoracic leg,neuron & nucleus & adult,oocyte,cell non-autonomous,germline clone,somatic clone,female germline stem cell,Cajal body,histone locus body,nucleolusda.G32" FBgn0266310 CR44975 http://flybase.net/reports/FBgn0266310.html non_protein_coding_gene CR44975 16-Dec-15 2015_12 FBgn0031088 CG15322 http://flybase.net/reports/FBgn0031088.html protein_coding_gene CG15322 16-Dec-15 2015_12 lethal FBgn0032122 CG31883 http://flybase.net/reports/FBgn0032122.html "FBgn0044654, FBgn0051883" protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG17022, anon-WO0140519.218" CG31883 16-Dec-15 2015_12 viable FBgn0005092 fs(2)OWc4 female sterile (2) OWc4 http://flybase.net/reports/FBgn0005092.html gene 16-Dec-15 2015_12 FBgn0058343 CG40343 http://flybase.net/reports/FBgn0058343.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267693 CR46029 http://flybase.net/reports/FBgn0267693.html non_protein_coding_gene CR46029 16-Dec-15 2015_12 FBgn0000651 febB feeding behavior B http://flybase.net/reports/FBgn0000651.html gene 16-Dec-15 2015_12 "visible,behavior defective,recessive,feeding behavior defective,somatic clone" FBgn0031826 CG9550 http://flybase.net/reports/FBgn0031826.html protein_coding_gene 0008459=chondroitin 6-sulfotransferase activity d6ST2 "IPR000863=Sulfotransferase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9550 16-Dec-15 2015_12 "ENSDARG00000058071(LOC100002270),ENSDARG00000070640,ENSDARG00000061070(LOC559721),ENSDARG00000061357(zgc:194879),ENSDARG00000044341(LOC563748)" "ENSXETG00000019025(TNeu013b01.1),ENSXETG00000001015(CHST1),ENSXETG00000014798(),ENSXETG00000003576(),ENSXETG00000022131(chst2),ENSXETG00000004136(CHST7)" "ENSMUSG00000035930(Chst4),ENSMUSG00000031952(Chst5),ENSMUSG00000037347(Chst7),ENSMUSG00000033350(Chst2),ENSMUSG00000057337(Chst3),ENSMUSG00000027221(Chst1)" "ENSG00000140835(CHST4),ENSG00000183196(CHST6),ENSG00000135702(CHST5),ENSG00000147119(CHST7),ENSG00000175040(CHST2),ENSG00000175264(CHST1),ENSG00000122863(CHST3)" viable FBgn0030777 CG9672 http://flybase.net/reports/FBgn0030777.html FBgn0047310 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BcDNA:GH16384, SPH161" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG9672 16-Dec-15 2015_12 viable FBgn0011167 l(1)DM-4 lethal (1) DM-4 http://flybase.net/reports/FBgn0011167.html FBgn0010204 gene 16-Dec-15 2015_12 lethal FBgn0003243 rfr refringent http://flybase.net/reports/FBgn0003243.html gene 0048477=oogenesis ref 16-Dec-15 2015_12 "female sterile,recessive,visible,viable,male,male fertile,female,reduced" wing FBgn0034942 CG13566 http://flybase.net/reports/FBgn0034942.html protein_coding_gene CG13566 16-Dec-15 2015_12 viable DRSC04203 I -1.617712005 -1.058909333 -0.100310023 0.839259811 0.769476694 0.777256016 FBgn0026873 MED18 Mediator complex subunit 18 http://flybase.net/reports/FBgn0026873.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0006357=regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter" "0016592=mediator complex, 0005634=nucleus" "dp28b, p28, Med18, p28/CG14802, EG:63B12.13, CG14802, Srb5/Med28b" "IPR019095=Mediator complex, subunit Med18, metazoa/fungi" CG14802 16-Dec-15 2015_12 ENSDARG00000041237(med18) WBGene00007018(mdt-18) ENSXETG00000020654(med18) ENSMUSG00000066042(Med18) ENSG00000130772(MED18) "cell growth defective,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,chaeta,supernumerary" FBgn0025356 Src64B::tub Src64B::tub http://flybase.net/reports/FBgn0025356.html engineered_fusion_gene src-tube 16-Dec-15 2015_12 FBgn0020566 anon-88Ad anon-88Ad http://flybase.net/reports/FBgn0020566.html gene unnamed 16-Dec-15 2015_12 FBgn0001521 l(1)11Ae lethal (1) 11Ae http://flybase.net/reports/FBgn0001521.html gene "l(1)L2, 2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0259990 CG42487 http://flybase.net/reports/FBgn0259990.html protein_coding_gene CG42487 16-Dec-15 2015_12 FBgn0030871 CG8142 http://flybase.net/reports/FBgn0030871.html protein_coding_gene "0003677=DNA binding, 0005524=ATP binding" "0031122=cytoplasmic microtubule organization, 0006260=DNA replication, 0046331=lateral inhibition" "0005663=DNA replication factor C complex, 0005875=microtubule associated complex" "DmRFC2, RfC, RFC2" "IPR003593=AAA+ ATPase domain, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008921=DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748=Replication factor C, C-terminal" CG8142 16-Dec-15 2015_12 ENSDARG00000042458(rfc4) YJR068W(RFC2) WBGene00004340(rfc-4) ENSXETG00000019391(rfc4) ENSMUSG00000022881(Rfc4) ENSG00000163918(RFC4) "viable,fertile,visible" "chaeta,trichogen cell" FBgn0039387 MCO3 multicopper oxidase 3 http://flybase.net/reports/FBgn0039387.html protein_coding_gene "0005381=iron ion transmembrane transporter activity, 0004322=ferroxidase activity, 0008447=L-ascorbate oxidase activity, 0005507=copper ion binding" "0055114=oxidation-reduction process, 0055070=copper ion homeostasis" "Multicopper oxidase, CG5959" "IPR008972=Cupredoxin, IPR011707=Multicopper oxidase, type 3, IPR011706=Multicopper oxidase, type 2, IPR001117=Multicopper oxidase, type 1, IPR002355=Multicopper oxidase, copper-binding site" CG5959 16-Dec-15 2015_12 "YMR058W(FET3),YFL041W(FET5)" WBGene00009008(F21D5.3) "viable,fertile" FBgn0262103 Sik3 Salt-inducible kinase 3 http://flybase.net/reports/FBgn0262103.html "FBgn0034376, FBgn0034378" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0042594=response to starvation, 0055088=lipid homeostasis, 0006468=protein phosphorylation" "EMK/KIAA0999, CG18604, SIK, SIK3, CG42856, CG15072" "IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR001772=Kinase associated domain 1 (KA1), IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR028375=KA1 domain/Ssp2 C-terminal domain, IPR011009=Protein kinase-like domain" CG42856 16-Dec-15 2015_12 YER129W(SAK1) FBgn0021774 ms(2)985 ms(2)985 http://flybase.net/reports/FBgn0021774.html gene ms-985 16-Dec-15 2015_12 "male sterile,recessive,viable" FBgn0083285 E(smoDN)2135 Enhancer of smoDN 2135 http://flybase.net/reports/FBgn0083285.html gene 16-Dec-15 2015_12 FBgn0250897 zaa43d06 http://flybase.net/reports/FBgn0250897.html gene zaa43d06x1 16-Dec-15 2015_12 FBgn0015563 vivi-repeat vivi-repeat http://flybase.net/reports/FBgn0015563.html FBgn0025236 repeat_region "vivi-sequence, Vivi, HP1-VS, VS, anon-EST:fe2A2, anon-fast-evolving-2A2" 16-Dec-15 2015_12 FBgn0034210 CG6568 http://flybase.net/reports/FBgn0034210.html protein_coding_gene CG6568 16-Dec-15 2015_12 viable FBgn0020255 Ran Ran http://flybase.net/reports/FBgn0020255.html "FBgn0026685, FBgn0030273" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity, 0005515=protein binding" "0007264=small GTPase mediated signal transduction, 0009267=cellular response to starvation, 0007346=regulation of mitotic cell cycle, 0048812=neuron projection morphogenesis, 0000212=meiotic spindle organization, 0006913=nucleocytoplasmic transport, 0006886=intracellular protein transport, 0008360=regulation of cell shape, 0007155=cell adhesion, 0007015=actin filament organization, 0032880=regulation of protein localization, 0000132=establishment of mitotic spindle orientation" "0005880=nuclear microtubule, 0005875=microtubule associated complex, 0005938=cell cortex, 0072686=mitotic spindle, 0005811=lipid particle, 0005634=nucleus, 0005737=cytoplasm" "CG1404, ran, l(1)G0075, Q9VZ23, ran10A, Ran, Ran GTPase, RanGTP, AAF30287, dran, ran GTPase" "IPR002041=Ran GTPase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG1404 16-Dec-15 2015_12 ENSDARG00000057026(ran) "YOR185C(GSP2),YLR293C(GSP1)" WBGene00004302(ran-1) ENSXETG00000027832(ran) "ENSMUSG00000029430(Ran),ENSMUSG00000083649(Rasl2-9-ps),ENSMUSG00000028287(1700009N14Rik)" ENSG00000132341(RAN) embryonic stage organism

"viable,wild-type,female sterile,male sterile,lethal,fertile,partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage" "karyosome,meiotic spindlenos.UTR.THsimVP16,ommatidium,photoreceptor cell,photoreceptor cell R7,cone cell,pigment cell" DRSC20364 I -1.583757533 0.054210938 -1.360761974 -0.590233519 0.303333163 0.629600729 FBgn0050021 metro menage a trois http://flybase.net/reports/FBgn0050021.html "FBgn0033585, FBgn0033586" protein_coding_gene 0004385=guanylate kinase activity "0048812=neuron projection morphogenesis, 0008582=regulation of synaptic growth at neuromuscular junction" "0071212=subsynaptic reticulum, 0005886=plasma membrane" "CG18338, CG13219, CG30021, FBgn0050021, skf, Metro, skiff" "IPR001452=SH3 domain, IPR020590=Guanylate kinase, conserved site, IPR001478=PDZ domain, IPR011511=Variant SH3 domain, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008144=Guanylate kinase-like domain, IPR004172=L27 domain" CG30021 16-Dec-15 2015_12 "ENSDARG00000008366(mpp7),ENSDARG00000015184(LOC572079),ENSDARG00000062667(LOC799884)" WBGene00021914(Y55B1BR.4) ENSXETG00000004546(MPP7) "ENSMUSG00000057440(Mpp7),ENSMUSG00000052373(Mpp3)" "ENSG00000150054(MPP7),ENSG00000161647(MPP3)" "viable,fertile,neuroanatomy defective" neuromuscular junction FBgn0086666 snoRNA:ë¬28S-2179 snoRNA:ë¬28S-2179 http://flybase.net/reports/FBgn0086666.html "FBgn0065054, FBgn0082991, FBgn0053918" snoRNA_gene 0005730=nucleolus "snoRNA:734, CR33918, Psi28S-2719(SnoR734), snoR734, psi28S-2179, SnoR734, Psi28S-2719, Dm-734" CR33918 16-Dec-15 2015_12 FBgn0015918 cant cat of nine tails http://flybase.net/reports/FBgn0015918.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086392 BG02053 http://flybase.net/reports/FBgn0086392.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0000386 ctt contorted http://flybase.net/reports/FBgn0000386.html gene 16-Dec-15 2015_12 "visible,recessive,female sterile,male fertile" "wing,eye,macrochaeta,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,genitalia,male,orbital bristle,male genitalia" FBgn0014378 raz razorback http://flybase.net/reports/FBgn0014378.html gene 16-Dec-15 2015_12 FBgn0015554 ttp tip-tap http://flybase.net/reports/FBgn0015554.html gene 16-Dec-15 2015_12 FBgn0001350 l(1)1Ee lethal (1) 1Ee http://flybase.net/reports/FBgn0001350.html gene 16-Dec-15 2015_12 lethal FBgn0265946 CR44733 http://flybase.net/reports/FBgn0265946.html non_protein_coding_gene CR44733 16-Dec-15 2015_12 FBgn0069224 gl(2R)18-14 gl(2R)18-14 http://flybase.net/reports/FBgn0069224.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal,germline clone,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,embryonic head,denticle belt" FBgn0001323 knrl knirps-like http://flybase.net/reports/FBgn0001323.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity" "0007424=open tracheal system development, 0007088=regulation of mitotic nuclear division, 0035151=regulation of tube size, open tracheal system, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0007427=epithelial cell migration, open tracheal system, 0043401=steroid hormone mediated signaling pathway, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "knirps-related, knl, Knrl, NR0A2, knirps related, Knirps-related, CG4761" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR013088=Zinc finger, NHR/GATA-type, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG4761 16-Dec-15 2015_12 " embryonic stage | cellular blastoderm , embryonic stage , larval stage , embryonic stage | embryonic cycle 12 , larval stage | third instar , embryonic stage | 70% egg length , organism | 80-100% egg length & ventral

, wing vein L2 | precursor

,

ubiquitous , organism | 20-30% egg length

" "mitotic cell cycle defective,visible,viable" "dorsal closure embryo,embryonic dorsal epidermis,metathoracic femur,adult thorax & macrochaetaBx-MS1096" FBgn0263909 l(3)B57 http://flybase.net/reports/FBgn0263909.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0045968 Tabor\pol pol http://flybase.net/reports/FBgn0045968.html transposable_element_gene "ORF2, Pilgrim\pol" 16-Dec-15 2015_12 FBgn0003309 sable sable http://flybase.net/reports/FBgn0003309.html gene 0048066=developmental pigmentation "ebonized, eb, s, ebonised" 16-Dec-15 2015_12 "visible,recessive,body color defective,female sterile,viable,male,male fertile" "wing,scutellum,trident" FBgn0267928 CR46209 http://flybase.net/reports/FBgn0267928.html non_protein_coding_gene lincRNA.196 CR46209 16-Dec-15 2015_12 FBgn0067882 Mod(Prat:bw)1-5 Mod(Prat:bw)1-5 http://flybase.net/reports/FBgn0067882.html gene Mod-1-5 16-Dec-15 2015_12 enhancer of variegation FBgn0038965 mats mob as tumor suppressor http://flybase.net/reports/FBgn0038965.html FBgn0062109 protein_coding_gene "0019901=protein kinase binding, 0005515=protein binding" "0007059=chromosome segregation, 0008283=cell proliferation, 0006915=apoptotic process, 0071174=mitotic spindle checkpoint, 0007165=signal transduction, 0007275=multicellular organismal development" "0005829=cytosol, 0005813=centrosome, 0005634=nucleus, 0005886=plasma membrane" "CG13852, Mats, Mob as tumor suppresso, mats, anon-WO0118547.303, DMob1, Mob1, Mob as tumor suppressor, Dmob1, dmob1" IPR005301=MOB kinase activator family CG13852 16-Dec-15 2015_12 "ENSDARG00000009169(mobkl1aa),ENSDARG00000012953(mobkl1ab),ENSDARG00000051980" YIL106W(MOB1) "ENSXETG00000023648(MOBKL1A),ENSXETG00000012095(mobk1b)" "ENSMUSG00000043131(Mobkl1b),ENSMUSG00000006262(Mobkl1a)" "ENSG00000173542(MOBKL1A),ENSG00000114978(MOBKL1B)" "neuroanatomy defective,somatic clone,tumorigenic,dominant,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,visible,body color defective,viable,wild-type,mitotic cell cycle defective" "imaginal disc,adult mushroom body,somatic clone,humerus,anepisternum,denticle,wing,wing hair,supernumerary,trichogen cell,mesothoracic tergum" DRSC14702 K 0.085228639 0.658521368 0.285839586 0.376705118 -0.522239165 3.279516468 FBgn0266777 CR45242 http://flybase.net/reports/FBgn0266777.html non_protein_coding_gene CR45242 16-Dec-15 2015_12 FBgn0013932 E(DTW) E(DTW) http://flybase.net/reports/FBgn0013932.html gene 16-Dec-15 2015_12 FBgn0085662 CG41517 http://flybase.net/reports/FBgn0085662.html FBan0041517 protein_coding_gene 16-Dec-15 2015_12 FBgn0031108 CG15459 http://flybase.net/reports/FBgn0031108.html protein_coding_gene CG15459 16-Dec-15 2015_12 FBgn0262683 CG43153 http://flybase.net/reports/FBgn0262683.html protein_coding_gene lincRNA.110 CG43153 16-Dec-15 2015_12 FBgn0004852 Ac76E Adenylyl cyclase 76E http://flybase.net/reports/FBgn0004852.html protein_coding_gene 0004016=adenylate cyclase activity "0002165=instar larval or pupal development, 0035556=intracellular signal transduction, 0006171=cAMP biosynthetic process, 0042594=response to starvation, 0040015=negative regulation of multicellular organism growth" "adenylyl cyclase, AdenylateCyclase E, AC 76E, DAC76E, ac76e, CG7978, DAC2, AC76E" "IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase" CG7978 16-Dec-15 2015_12 "ENSDARG00000058392(adcy2a),ENSDARG00000014588(adcy2b)" WBGene00000069(acy-2) ENSXETG00000016889(ADCY4) "ENSMUSG00000021536(Adcy2),ENSMUSG00000022220(Adcy4),ENSMUSG00000031659(Adcy7)" "ENSG00000078295(ADCY2),ENSG00000129467(ADCY4),ENSG00000121281(ADCY7)" "developmental rate defective,body size defective,starvation stress response defective,female limited" FBgn0010072 Mab66B2 Monoclonal antibody 66B2 http://flybase.net/reports/FBgn0010072.html gene 66B2 antigen 16-Dec-15 2015_12 " larval stage , embryonic stage | 12-15 hr , pupal stage , embryonic stage " " imaginal disc

, embryonic/larval hindgut

, optic lobe

, epidermis

, neuropil

, central nervous system

, embryonic/larval foregut

, embryonic/larval trachea

, Keilin's organ

" FBgn0039876 CG2126 http://flybase.net/reports/FBgn0039876.html FBgn0062028 protein_coding_gene anon-WO0118547.412 IPR008485=Protein of unknown function DUF766 CG2126 16-Dec-15 2015_12 ENSDARG00000028581(jkamp) WBGene00019807(jamp-1) ENSXETG00000017024(JKAMP) "ENSMUSG00000005078(Jkamp),ENSMUSG00000056197(4931417E11Rik)" ENSG00000050130(JKAMP) viable DRSC15418 E 0.863364304 0.056081719 -0.335910605 -2.634622219 1.088719498 -1.103259431 FBgn0022089 l(2)k07315 lethal (2) k07315 http://flybase.net/reports/FBgn0022089.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005087 fs(2)OW811 female sterile (2) OW811 http://flybase.net/reports/FBgn0005087.html gene 16-Dec-15 2015_12 FBgn0061483 rover\gag gag http://flybase.net/reports/FBgn0061483.html transposable_element_gene 16-Dec-15 2015_12 FBgn0000933 fs(2)A3 female sterile (2) A3 http://flybase.net/reports/FBgn0000933.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0032562 CG18483 http://flybase.net/reports/FBgn0032562.html protein_coding_gene "BG:DS07851.10, Ms(2)35Ci" 16-Dec-15 2015_12 FBgn0013484 l(1)4Fb lethal (1) 4Fb http://flybase.net/reports/FBgn0013484.html gene 16-Dec-15 2015_12 lethal FBgn0065372 l(2)SH1694 lethal (2) SH1694 http://flybase.net/reports/FBgn0065372.html gene l(2)SH2 1694 16-Dec-15 2015_12 "lethal,recessive" FBgn0004758 l(3)89Bk lethal (3) 89Bk http://flybase.net/reports/FBgn0004758.html gene 16-Dec-15 2015_12 lethal FBgn0014148 dkn deathknell http://flybase.net/reports/FBgn0014148.html gene 16-Dec-15 2015_12 FBgn0041091 ubi-d4 ubi-d4 http://flybase.net/reports/FBgn0041091.html gene unnamed 16-Dec-15 2015_12 FBgn0001508 l(1)10Fb lethal (1) 10Fb http://flybase.net/reports/FBgn0001508.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone,egg" FBgn0013516 l(1)XWJ lethal (1) XWJ http://flybase.net/reports/FBgn0013516.html gene XWJ 16-Dec-15 2015_12 FBgn0001916 l(2)25Bc lethal (2) 25Bc http://flybase.net/reports/FBgn0001916.html gene "l(2)jf12, jf12" 16-Dec-15 2015_12 lethal FBgn0000753 fs(1)A426 female sterile (1) A426 http://flybase.net/reports/FBgn0000753.html gene 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" embryo FBgn0036937 Ir76b Ionotropic receptor 76b http://flybase.net/reports/FBgn0036937.html protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0004984=olfactory receptor activity, 0015276=ligand-gated ion channel activity, 0033039=salty taste receptor activity, 0005272=sodium channel activity" "0035199=salt aversion, 1902075=cellular response to salt, 0019226=transmission of nerve impulse, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0009593=detection of chemical stimulus" "0043235=receptor complex, 0016020=membrane, 0071683=sensory dendrite, 0016021=integral component of membrane" "DmelIR76b, ir76b, IR76b, CT22733, ionotropic receptor 76b, CG7385" IPR001320=Ionotropic glutamate receptor CG7385 16-Dec-15 2015_12 "ENSXETG00000023280(GRID2),ENSXETG00000011804(GRIK1),ENSXETG00000021375()" "neurophysiology defective,chemosensitive behavior defective,viable" "L-type sensilla L6,L-type sensilla L4,L-type sensilla L2" FBgn0265422 CR44334 http://flybase.net/reports/FBgn0265422.html non_protein_coding_gene CR44334 16-Dec-15 2015_12 FBgn0046117 E(To)9 E(To)9 http://flybase.net/reports/FBgn0046117.html gene 16-Dec-15 2015_12 "sterile,recessive,viable,visible" "dorsal appendage,eye,wing margin" FBgn0265640 CR44447 http://flybase.net/reports/FBgn0265640.html non_protein_coding_gene CR44447 16-Dec-15 2015_12 FBgn0263031 CG43326 http://flybase.net/reports/FBgn0263031.html "FBgn0034757, FBan0030217, FBgn0050217" protein_coding_gene "CG30217, CG13514" IPR006629=LPS-induced tumour necrosis factor alpha factor CG43326 16-Dec-15 2015_12 FBgn0040787 CG12518 http://flybase.net/reports/FBgn0040787.html protein_coding_gene 16-Dec-15 2015_12 FBgn0022088 l(2)k07332 lethal (2) k07332 http://flybase.net/reports/FBgn0022088.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0002911 mwg micro-wing http://flybase.net/reports/FBgn0002911.html gene microwing 16-Dec-15 2015_12 "visible,fertile,viable" "wing,haltere" FBgn0084004 CG41437 http://flybase.net/reports/FBgn0084004.html FBan0041437 protein_coding_gene 16-Dec-15 2015_12 FBgn0062564 P10 P10 http://flybase.net/reports/FBgn0062564.html gene 16-Dec-15 2015_12 FBgn0022110 l(2)k06918 lethal (2) k06918 http://flybase.net/reports/FBgn0022110.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039779 PH4ë±SG2 prolyl-4-hydroxylase-alpha SG2 http://flybase.net/reports/FBgn0039779.html protein_coding_gene "0005506=iron ion binding, 0004656=procollagen-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" "0007435=salivary gland morphogenesis, 0055114=oxidation-reduction process" "0005783=endoplasmic reticulum, 0016222=procollagen-proline 4-dioxygenase complex" "PH4alphaSG2, CG1546, SG2" "IPR011990=Tetratricopeptide-like helical domain, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG1546 16-Dec-15 2015_12 viable FBgn0036489 CG7011 http://flybase.net/reports/FBgn0036489.html protein_coding_gene 0006888=ER to Golgi vesicle-mediated transport 0030134=ER to Golgi transport vesicle "IPR012936=Endoplasmic reticulum vesicle transporter, C-terminal" CG7011 16-Dec-15 2015_12 ENSDARG00000038074(ergic3) YAL042W(ERV46) WBGene00010725(erv-46) ENSXETG00000007419(SDBCAG84) ENSMUSG00000005881(Ergic3) ENSG00000125991(ERGIC3) viable FBgn0260630 f06222 http://flybase.net/reports/FBgn0260630.html gene 16-Dec-15 2015_12 FBgn0045860 crle crippled leg http://flybase.net/reports/FBgn0045860.html gene 16-Dec-15 2015_12 FBgn0004078 Ars-region13 Autonomous replicating sequence region 13 http://flybase.net/reports/FBgn0004078.html region "Ars13, Ars sequence 13" 16-Dec-15 2015_12 FBgn0025687 LKRSDH Lysine ketoglutarate reductase/saccharopine dehydrogenase http://flybase.net/reports/FBgn0025687.html "FBgn0031949, FBgn0045950" protein_coding_gene "0004754=saccharopine dehydrogenase (NAD+, L-lysine-forming) activity" "0031060=regulation of histone methylation, 0034969=histone arginine methylation, 0055114=oxidation-reduction process" "lysine ketoglutarate reductase, saccharopine dehydogenase, CK02318, Drosophila lysine ketoglutarate reductase (dLKR)/saccharopine dehydrogenase (SDH), dLKR, SDH, Drosophila lysine ketoglutarate reductase, CG7144, LKR, anon-WO0149856.1, BEST:CK02318" "IPR016040=NAD(P)-binding domain, IPR005097=Saccharopine dehydrogenase, NADP binding domain, IPR007698=Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain, IPR007886=Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal" CG7144 16-Dec-15 2015_12 ENSDARG00000051816(aass) WBGene00019819(R02D3.1) ENSXETG00000022747(Q5I0C2_XENTR) ENSMUSG00000029695(Aass) ENSG00000008311(AASS) pupal stage salivary gland

"viable,fertile" wing FBgn0038201 PK1-R Pyrokinin 1 receptor http://flybase.net/reports/FBgn0038201.html "FBgn0046613, FBgn0046614" protein_coding_gene "0008188=neuropeptide receptor activity, 0036401=pyrokinin receptor activity, 0004930=G-protein coupled receptor activity" "0007218=neuropeptide signaling pathway, 0090278=negative regulation of peptide hormone secretion, 0070328=triglyceride homeostasis, 0007186=G-protein coupled receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "Pk1R, Pk1r, CG9918, Drm-PK-1 receptor, pyrokinin-1 receptor, Lst receptor, anon-WO0170980.112, anon-WO0170980.113, Pyrokinin 1 receptor" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG9918 16-Dec-15 2015_12 ENSDARG00000060884(LOC557276) WBGene00016265(nmur-4) "viable,fertile" FBgn0086417 l(3)CHa lethal (3) CHa http://flybase.net/reports/FBgn0086417.html gene complementation group 1 16-Dec-15 2015_12 "lethal,recessive" FBgn0004067 fs(2)mel1 female sterile (2) maternal effect lethal 1 http://flybase.net/reports/FBgn0004067.html gene mel 1 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "egg,maternal effect,embryo" FBgn0259713 CG42367 http://flybase.net/reports/FBgn0259713.html "FBan0031711, FBan0031878, FBgn0051711, FBgn0051878" protein_coding_gene 0042302=structural constituent of cuticle "CG31878, CG4588" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG42367 16-Dec-15 2015_12 "viable,fertile" FBgn0050020 CG30020 http://flybase.net/reports/FBgn0050020.html "FBgn0033567, FBgn0033568, FBgn0065031" protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding, 0003676=nucleic acid binding" 0005634=nucleus "CG18353, BEST:LD40262, CG12941, p190" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG30020 16-Dec-15 2015_12 "viable,fertile" DRSC06730 K 1.032061316 0.017303785 0.417735398 -0.024358721 -1.79978409 -0.412861659 FBgn0085591 CG41274 http://flybase.net/reports/FBgn0085591.html FBan0041274 protein_coding_gene 16-Dec-15 2015_12 FBgn0031452 Cwc25 Cwc25 http://flybase.net/reports/FBgn0031452.html protein_coding_gene 0007052=mitotic spindle organization "CG2843, CWC25" "IPR019339=CBF1-interacting co-repressor CIR, N-terminal domain, IPR022209=Pre-mRNA splicing factor" CG2843 16-Dec-15 2015_12 ENSDARG00000003382(cwc25) WBGene00018677(F52C9.7) ENSXETG00000023722(CWC25) ENSMUSG00000018541(Cwc25) ENSG00000108296(CWC25) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266005 CR44779 http://flybase.net/reports/FBgn0266005.html non_protein_coding_gene CR44779 16-Dec-15 2015_12 FBgn0083240 EP2204 EP2204 http://flybase.net/reports/FBgn0083240.html gene 16-Dec-15 2015_12 FBgn0021986 l(2)k09801 lethal (2) k09801 http://flybase.net/reports/FBgn0021986.html gene P918 16-Dec-15 2015_12 "lethal,recessive" FBgn0041234 Gr59f Gustatory receptor 59f http://flybase.net/reports/FBgn0041234.html "FBgn0034875, FBgn0053150" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 59E.1, GR59E.1, 59E.1, CG33150, CG5365, Gr59E1" IPR013604=7TM chemoreceptor CG33150 16-Dec-15 2015_12 partially lethal - majority die FBgn0020581 anon-59Cd anon-59Cd http://flybase.net/reports/FBgn0020581.html gene 16-Dec-15 2015_12 FBgn0043026 l(2)42Fa lethal (2) 42Fa http://flybase.net/reports/FBgn0043026.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266921 ft::Hsap\FAT4 http://flybase.net/reports/FBgn0266921.html engineered_fusion_gene Fat:Fat4 16-Dec-15 2015_12 FBgn0031513 CG3347 http://flybase.net/reports/FBgn0031513.html protein_coding_gene 0008270=zinc ion binding "IPR001965=Zinc finger, PHD-type, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG3347 16-Dec-15 2015_12 viable DRSC00597 K 0.007647223 -0.538442014 -0.702709217 0.05744939 -0.050026463 1.621872587 FBgn0263960 BG01677 http://flybase.net/reports/FBgn0263960.html gene 16-Dec-15 2015_12 "long lived,starvation stress response defective,male limited" FBgn0036812 Nufip Nufip http://flybase.net/reports/FBgn0036812.html protein_coding_gene 0003729=mRNA binding 0005634=nucleus "NUFIP, CG4076" "IPR019496=Nuclear fragile X mental retardation-interacting protein 1, conserved domain, IPR015880=Zinc finger, C2H2-like" CG4076 16-Dec-15 2015_12 ENSXETG00000014778(nufip1) ENSG00000083635(NUFIP1) "viable,visible,lethal - all die before end of pupal stage" trichogen cell FBgn0052431 CG32431 http://flybase.net/reports/FBgn0052431.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000796 fs(1)de7 female sterile (1) defective eggs 7 http://flybase.net/reports/FBgn0000796.html gene de7 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion" FBgn0004505 fs(1)A5 female sterile (1) A5 http://flybase.net/reports/FBgn0004505.html gene 16-Dec-15 2015_12 FBgn0015454 l(2)24CDa lethal (2) 24CDa http://flybase.net/reports/FBgn0015454.html gene l(2)d 16-Dec-15 2015_12 lethal FBgn0039169 Spps Sp1-like factor for pairing sensitive-silencing http://flybase.net/reports/FBgn0039169.html protein_coding_gene "0046872=metal ion binding, 0043565=sequence-specific DNA binding" 0060968=regulation of gene silencing "0005634=nucleus, 0005704=polytene chromosome band" "Spps, Sp1-like factor for Pairing Sensitive-silencing, CG5669" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR030450=Transcription factor Sp1 family, IPR007087=Zinc finger, C2H2" CG5669 16-Dec-15 2015_12 "ENSXETG00000012660(Q6P817_XENTR),ENSXETG00000007429(SP4),ENSXETG00000008503(sp3)" "ENSMUSG00000025323(Sp4),ENSMUSG00000001280(Sp1),ENSMUSG00000027109(Sp3),ENSMUSG00000018678(Sp2)" "ENSG00000185591(SP1),ENSG00000105866(SP4),ENSG00000172845(SP3)" "lethal,recessive,germline clone,penetrance incomplete (obsolete FBcv0000019),partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,viable,visible" "wing,mesothoracic tergum" FBgn0003108 pallid pallid http://flybase.net/reports/FBgn0003108.html gene "pl, pld" 16-Dec-15 2015_12 "partially lethal - majority live,body color defective" wing FBgn0036814 CG14073 http://flybase.net/reports/FBgn0036814.html protein_coding_gene 0048190=wing disc dorsal/ventral pattern formation 0005876=spindle microtubule Nirvana "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG14073 16-Dec-15 2015_12 ENSDARG00000017798(bcor) "ENSMUSG00000036959(Bcorl1),ENSMUSG00000040363(Bcor)" ENSG00000183337(BCOR) viable FBgn0002463 l(3)SG16 lethal (3) SG16 http://flybase.net/reports/FBgn0002463.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032817 CG10631 http://flybase.net/reports/FBgn0032817.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR006612=Zinc finger, C2CH-type" CG10631 16-Dec-15 2015_12 viable FBgn0019740 l(1)91-1 lethal (1) 91-1 http://flybase.net/reports/FBgn0019740.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259302 EP-108 http://flybase.net/reports/FBgn0259302.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta" FBgn0044079 E(rst)H65 E(rst)H65 http://flybase.net/reports/FBgn0044079.html gene 0001745=compound eye morphogenesis H65 16-Dec-15 2015_12 viable eye FBgn0267030 CR45474 http://flybase.net/reports/FBgn0267030.html non_protein_coding_gene CR45474 16-Dec-15 2015_12 FBgn0010243 Mst77F-ë¬Y1 Mst77F pseudogene on Y 1 http://flybase.net/reports/FBgn0010243.html pseudogene_attribute "18c, Mst77-Psi1" 16-Dec-15 2015_12 FBgn0030190 CG2908 http://flybase.net/reports/FBgn0030190.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263851 snoRNA:CD-24 http://flybase.net/reports/FBgn0263851.html snoRNA_gene "CR43712, snoCD_24" CR43712 16-Dec-15 2015_12 FBgn0042697 N-fa-swb-INS Notch facet strawberry insulator element http://flybase.net/reports/FBgn0042697.html insulator "Fa[swb], fa[swb]" 16-Dec-15 2015_12 FBgn0005465 l(1)ts88 lethal (1) ts88 http://flybase.net/reports/FBgn0005465.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0031145 Ntf-2 Nuclear transport factor-2 http://flybase.net/reports/FBgn0031145.html "FBgn0027201, FBgn0027301, FBgn0027316, FBgn0040175, FBgn0062480" protein_coding_gene 0008320=protein transmembrane transporter activity "0006606=protein import into nucleus, 0002807=positive regulation of antimicrobial peptide biosynthetic process" 0005622=intracellular "NTF-2, Ntf2, dmNTF2, CG1740, ntf2, l(1)G0428, Dntf-2, Dntf2, DNTF-2, l(1)G0337, l(1)G0125, nuclear transport factor-2, ntf-2, BcDNA:GM08921, l(1)G0086" "IPR018222=Nuclear transport factor 2, eukaryote, IPR002075=Nuclear transport factor 2" CG1740 16-Dec-15 2015_12 "ENSDARG00000056531(zgc:101555),ENSDARG00000014499(nutf2)" YER009W(NTF2) WBGene00004305(ran-4) ENSXETG00000026897(nutf2) ENSMUSG00000008450(Nutf2) ENSG00000102898(NUTF2) " adult stage | male , adult stage | female " testis

"lethal,female,lethal - all die before end of larval stage,some die during larval stage,female fertile,viable,male,male fertile,visible,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during third instar larval stage,partially lethal - majority die,some die during pupal stage,female sterile" "eye,mesothoracic tergum" FBgn0014966 gypsy\pol gypsy\polymerase http://flybase.net/reports/FBgn0014966.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "RT, ORF2, DmeGypV int, pol, int, gypsy RTase, RTase" "IPR001584=Integrase, catalytic core, IPR000477=Reverse transcriptase domain, IPR021109=Aspartic peptidase domain, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0032723 ssp3 short spindle 3 http://flybase.net/reports/FBgn0032723.html FBgn0032722 protein_coding_gene 0000022=mitotic spindle elongation 0005819=spindle "CG18397, Ssp3, CG10666" CG18397 16-Dec-15 2015_12 ENSDARG00000023104(LOC100331891) ENSMUSG00000034007(Scaper) ENSG00000140386(SCAPER) "viable,fertile" FBgn0067055 Q9 Q9 http://flybase.net/reports/FBgn0067055.html gene 16-Dec-15 2015_12 "visible,lethal,viable" chaeta FBgn0036987 CG5274 http://flybase.net/reports/FBgn0036987.html protein_coding_gene IPR027844=Protein of unknown function DUF4507 CG5274 16-Dec-15 2015_12 ENSDARG00000037652(zgc:56409) ENSXETG00000017304(C7orf26) ENSMUSG00000039244(E130309D02Rik) ENSG00000146576(C7orf26) "viable,fertile" DRSC11774 I 1.6241633 -0.55302344 0.020185487 0.360656914 0.208308987 0.300474956 FBgn0044123 E(rst)B50 E(rst)B50 http://flybase.net/reports/FBgn0044123.html gene 0001745=compound eye morphogenesis B50 16-Dec-15 2015_12 viable "eye,cone cell,primary pigment cell,secondary pigment cell,ectopic,tertiary pigment cell,interommatidial bristle" FBgn0028025 l(3)S103603 lethal (3) S103603 http://flybase.net/reports/FBgn0028025.html gene 1036/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0041839 E(Sev-CycE)G66 E(Sev-CycE)G66 http://flybase.net/reports/FBgn0041839.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267091 CR45535 http://flybase.net/reports/FBgn0267091.html non_protein_coding_gene CR45535 16-Dec-15 2015_12 FBgn0014376 ptz pitzi http://flybase.net/reports/FBgn0014376.html gene 16-Dec-15 2015_12 FBgn0260032 siren2 siren 2 http://flybase.net/reports/FBgn0260032.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0024666 l(2)k05510 lethal (2) k05510 http://flybase.net/reports/FBgn0024666.html gene 55/10 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0003497 Sq Squat http://flybase.net/reports/FBgn0003497.html gene 16-Dec-15 2015_12 "lethal,recessive" "leg,head,adult thorax" FBgn0031092 CG9577 http://flybase.net/reports/FBgn0031092.html protein_coding_gene "0008416=delta5-delta2,4-dienoyl-CoA isomerase activity" "0006635=fatty acid beta-oxidation, 0008152=metabolic process" "0005811=lipid particle, 0005777=peroxisome" "IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily, IPR014748=Crontonase, C-terminal" CG9577 16-Dec-15 2015_12 ENSDARG00000012915(zgc:101710) "WBGene00021296(Y25C1A.13),WBGene00019022(F58A6.1)" ENSXETG00000000036(ech1) ENSMUSG00000053898(Ech1) ENSG00000104823(ECH1) viable FBgn0037726 CG9492 http://flybase.net/reports/FBgn0037726.html protein_coding_gene "0003774=motor activity, 0016887=ATPase activity, 0003777=microtubule motor activity, 0042623=ATPase activity, coupled, 0005524=ATP binding" "0007605=sensory perception of sound, 0007018=microtubule-based movement" "0030286=dynein complex, 0005875=microtubule associated complex, 0005858=axonemal dynein complex" "IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013594=Dynein heavy chain, domain-1, IPR004273=Dynein heavy chain domain, IPR011704=ATPase, dynein-related, AAA domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR024743=Dynein heavy chain, coiled coil stalk" CG9492 16-Dec-15 2015_12 ENSDARG00000056888 ENSXETG00000021408() "ENSMUSG00000022262(Dnahc5),ENSMUSG00000033826(Dnahc8)" "ENSG00000039139(DNAH5),ENSG00000124721(DNAH8)" "auditory perception defective,neurophysiology defective" FBgn0262563 CG43103 http://flybase.net/reports/FBgn0262563.html protein_coding_gene Dm_2R:55417 CG43103 16-Dec-15 2015_12 FBgn0044101 E(rst)C532 E(rst)C532 http://flybase.net/reports/FBgn0044101.html gene 0001745=compound eye morphogenesis C532 16-Dec-15 2015_12 viable FBgn0069427 JJF014 JJF014 http://flybase.net/reports/FBgn0069427.html gene 16-Dec-15 2015_12 stress response defective FBgn0029539 CG11663 http://flybase.net/reports/FBgn0029539.html FBgn0061466 protein_coding_gene BcDNA:AT05678 CG11663 16-Dec-15 2015_12 FBgn0010179 tu(2)49k tu(2)49k http://flybase.net/reports/FBgn0010179.html gene 16-Dec-15 2015_12 "visible,melanotic mass phenotype" melanotic mass FBgn0039675 ppk21 pickpocket 21 http://flybase.net/reports/FBgn0039675.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "PPK21, CG12048" "IPR001873=Na+ channel, amiloride-sensitive" CG12048 16-Dec-15 2015_12 viable FBgn0037935 CG6834 http://flybase.net/reports/FBgn0037935.html protein_coding_gene 0017022=myosin binding "IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227" CG6834 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0002234 l(3)68Ba lethal (3) 68Ba http://flybase.net/reports/FBgn0002234.html FBgn0002230 gene "l(3)C141, A, Complementation group A, l(3)A" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266493 s-108 http://flybase.net/reports/FBgn0266493.html gene 16-Dec-15 2015_12 FBgn0037044 CG10585 http://flybase.net/reports/FBgn0037044.html protein_coding_gene 0000010=trans-hexaprenyltranstransferase activity 0008299=isoprenoid biosynthetic process "IPR008949=Isoprenoid synthase domain, IPR000092=Polyprenyl synthetase, IPR017446=Polyprenyl synthetase-related" CG10585 16-Dec-15 2015_12 ENSDARG00000012563(pdss2) ENSXETG00000019263(Q640V1_XENTR) ENSMUSG00000038240(Pdss2) ENSG00000164494(PDSS2) "viable,fertile,lethal,partially lethal - majority die,visible" "embryonic/larval hemocyte | third instar larval stage,mesothoracic tergum" FBgn0267173 CR45613 http://flybase.net/reports/FBgn0267173.html non_protein_coding_gene CR45613 16-Dec-15 2015_12 FBgn0020594 anon-57Cc anon-57Cc http://flybase.net/reports/FBgn0020594.html gene unnamed 16-Dec-15 2015_12 FBgn0058402 CG40402 http://flybase.net/reports/FBgn0058402.html FBan0040402 protein_coding_gene 16-Dec-15 2015_12 FBgn0010319 Cdi11 Cyclin-dependent kinase interactor 11 http://flybase.net/reports/FBgn0010319.html gene "CDI11, cdi11" 16-Dec-15 2015_12 FBgn0044002 Su(rst)C352 Su(rst)C352 http://flybase.net/reports/FBgn0044002.html gene 0001745=compound eye morphogenesis C352 16-Dec-15 2015_12 FBgn0264407 FCG-J http://flybase.net/reports/FBgn0264407.html gene FC G-J 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0015851 anon-10Cd anon-10Cd http://flybase.net/reports/FBgn0015851.html gene 16-Dec-15 2015_12 FBgn0065367 l(2)SH1715 lethal (2) SH1715 http://flybase.net/reports/FBgn0065367.html gene l(2)SH2 1715 16-Dec-15 2015_12 "lethal,recessive" FBgn0026353 Su(SuRaf1)2 Su(SuRaf1)2 http://flybase.net/reports/FBgn0026353.html gene Su[Su(Raf)1]2 16-Dec-15 2015_12 "lethal,recessive" FBgn0029522 CG13373 http://flybase.net/reports/FBgn0029522.html protein_coding_gene IPR022773=Siva CG13373 16-Dec-15 2015_12 ENSXETG00000024697(TEgg104k06.1) ENSMUSG00000064326(Siva1) "viable,fertile" FBgn0001007 fs(3)6m45 female sterile (3) 6m45 http://flybase.net/reports/FBgn0001007.html gene 16-Dec-15 2015_12 female sterile "oocyte,ovary" FBgn0033753 Cyp301a1 Cyp301a1 http://flybase.net/reports/FBgn0033753.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0007490=tergite morphogenesis" 0005739=mitochondrion "cytochrome P450, CG8587, 301a1, Cyp301A1" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG8587 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" "viable,fertile,visible,recessive,partially lethal - majority live,body color defective" "tergite,adult cuticle,mesothoracic tergum" FBgn0005687 pom pomegranate http://flybase.net/reports/FBgn0005687.html gene 0048749=compound eye development 16-Dec-15 2015_12 "visible,recessive" "eye,ommatidium" FBgn0043571 SK2-3 SK2-3 http://flybase.net/reports/FBgn0043571.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267074 CR45518 http://flybase.net/reports/FBgn0267074.html non_protein_coding_gene CR45518 16-Dec-15 2015_12 FBgn0038373 CG4546 http://flybase.net/reports/FBgn0038373.html protein_coding_gene 0004054=arginine kinase activity 0032504=multicellular organism reproduction 0005615=extracellular space "IPR022413=ATP:guanido phosphotransferase, N-terminal, IPR022415=ATP:guanido phosphotransferase active site, IPR022414=ATP:guanido phosphotransferase, catalytic domain, IPR000749=ATP:guanido phosphotransferase, IPR014746=Glutamine synthetase/guanido kinase, catalytic domain" CG4546 16-Dec-15 2015_12 viable FBgn0013454 fs(2)neo11 fs(2)neo11 http://flybase.net/reports/FBgn0013454.html gene unnamed 16-Dec-15 2015_12 "female sterile,fertile" FBgn0082189 l(3)S012606 lethal (3) S012606 http://flybase.net/reports/FBgn0082189.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264881 CG44072 http://flybase.net/reports/FBgn0264881.html protein_coding_gene CG44072 16-Dec-15 2015_12 FBgn0266850 CR45311 http://flybase.net/reports/FBgn0266850.html non_protein_coding_gene CR45311 16-Dec-15 2015_12 FBgn0031646 CG2837 http://flybase.net/reports/FBgn0031646.html protein_coding_gene CG2837 16-Dec-15 2015_12 lethal FBgn0063408 l(3)3450-O lethal (3) 3450-O http://flybase.net/reports/FBgn0063408.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0028468 rtet tetracycline resistance http://flybase.net/reports/FBgn0028468.html "FBgn0010915, FBgn0063806" protein_coding_gene 0051119=sugar transmembrane transporter activity "0055085=transmembrane transport, 0048477=oogenesis" 0016021=integral component of membrane "l(3)07086, anon-WO0119857.1, CG5760, BcDNA:LD28419, Drtet" "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG5760 16-Dec-15 2015_12 ENSDARG00000018641 "YMR088C(VBA1),YBR293W(VBA2)" WBGene00017339(F10D7.2) ENSXETG00000008016(TETRAN) ENSMUSG00000001082(Mfsd10) ENSG00000109736(MFSD10) "viable,fertile,lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,egg" FBgn0267037 CR45481 http://flybase.net/reports/FBgn0267037.html non_protein_coding_gene CR45481 16-Dec-15 2015_12 FBgn0260330 GSd482 http://flybase.net/reports/FBgn0260330.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0037175 CG14455 http://flybase.net/reports/FBgn0037175.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG14455 16-Dec-15 2015_12 viable FBgn0053127 CG33127 http://flybase.net/reports/FBgn0053127.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG33127 16-Dec-15 2015_12 FBgn0265597 rad radish http://flybase.net/reports/FBgn0265597.html "FBgn0030442, FBgn0030444, FBan0018646, FBgn0030450, FBgn0003193, FBgn0261379, FBgn0250864, FBgn0259161, FBgn0261351, FBgn0261388, FBgn0261352, FBgn0030445" protein_coding_gene "0008270=zinc ion binding, 0005096=GTPase activator activity" "0008355=olfactory learning, 0090630=activation of GTPase activity, 0007615=anesthesia-resistant memory, 0008016=regulation of heart contraction" "0005634=nucleus, 0005737=cytoplasm, 0030424=axon, 0043025=neuronal cell body" "CG44424, rsh, CG42629, Rad, radish, CG4346, CG42628, CG4368, CG18646, CG15720" "IPR000210=BTB/POZ domain, IPR001781=Zinc finger, LIM-type, IPR011333=POZ domain, IPR000331=Rap GTPase activating protein domain" CG44424 16-Dec-15 2015_12 DRSC22865 IE -1.527563262 -0.024275387 -0.767896929 -1.776137846 -0.466784737 -0.017405572 FBgn0061166 l(1)3Ar lethal (1) 3Ar http://flybase.net/reports/FBgn0061166.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035878 CG7182 http://flybase.net/reports/FBgn0035878.html protein_coding_gene 0009408=response to heat IPR013126=Heat shock protein 70 family CG7182 16-Dec-15 2015_12 viable embryonic/larval hemocyte | third instar larval stage FBgn0019885 anon-63BC-T2 anon-63BC-T2 http://flybase.net/reports/FBgn0019885.html gene "63B-T2, T2" 16-Dec-15 2015_12 FBgn0038653 CG18208 http://flybase.net/reports/FBgn0038653.html protein_coding_gene "0032795=heterotrimeric G-protein binding, 0008227=G-protein coupled amine receptor activity" 0007186=G-protein coupled receptor signaling pathway 0005887=integral component of plasma membrane "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG18208 16-Dec-15 2015_12 "ENSDARG00000054667(adra2db),ENSDARG00000042315(adra2da),ENSDARG00000040841(adra2a),ENSDARG00000019819,ENSDARG00000041008" WBGene00006411(octr-1) "ENSXETG00000015427(ADRA2C),ENSXETG00000007246()" "ENSMUSG00000045318(Adra2c),ENSMUSG00000033717(Adra2a),ENSMUSG00000058620(Adra2b)" "ENSG00000184160(ADRA2C),ENSG00000150594(ADRA2A),ENSG00000222040(ADRA2B)" "viable,fertile,visible" mesothoracic tergum FBgn0035648 CG13288 http://flybase.net/reports/FBgn0035648.html protein_coding_gene dmCG13288 CG13288 16-Dec-15 2015_12 viable FBgn0266107 mei-175 meiotic 175 http://flybase.net/reports/FBgn0266107.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female" FBgn0083999 CG41432 http://flybase.net/reports/FBgn0083999.html FBan0041432 protein_coding_gene 16-Dec-15 2015_12 FBgn0267245 CR45685 http://flybase.net/reports/FBgn0267245.html non_protein_coding_gene CR45685 16-Dec-15 2015_12 FBgn0052068 Adi1 Acireductone dioxygenase 1 http://flybase.net/reports/FBgn0052068.html FBgn0036097 protein_coding_gene "0016491=oxidoreductase activity, 0010309=acireductone dioxygenase [iron(II)-requiring] activity" "0006555=methionine metabolic process, 0055114=oxidation-reduction process, 0019509=L-methionine biosynthetic process from methylthioadenosine" "0005737=cytoplasm, 0005634=nucleus, 0005886=plasma membrane" "CG32068, CG8000, aci-reductone dioxygenase 1, Dadi1, adi1" "IPR014710=RmlC-like jelly roll fold, IPR004313=Acireductone dioxygenase ARD family, IPR027496=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes, IPR011051=RmlC-like cupin domain" CG32068 16-Dec-15 2015_12 ENSDARG00000020448(adi1) YMR009W(ADI1) WBGene00009636(F42F12.4) "ENSXETG00000000320(Q6DIY2_XENTR),ENSXETG00000001215()" ENSMUSG00000020629(Adi1) ENSG00000182551(ADI1) FBgn0031103 CG12679 http://flybase.net/reports/FBgn0031103.html protein_coding_gene CG12679 16-Dec-15 2015_12 FBgn0263464 snoRNA:hts-a http://flybase.net/reports/FBgn0263464.html snoRNA_gene snoHACA_05 CR43579 16-Dec-15 2015_12 FBgn0020757 Cyp6a9-rAF4-2 Cytochrome P450-6a9 related AF4-2 http://flybase.net/reports/FBgn0020757.html gene "AF4-2, Cyp6a9-related, P-450, P450" 16-Dec-15 2015_12 FBgn0267448 CR45798 http://flybase.net/reports/FBgn0267448.html non_protein_coding_gene noncoding_18124 CR45798 16-Dec-15 2015_12 FBgn0083950 CG34114 http://flybase.net/reports/FBgn0083950.html "FBan0004695, FBgn0037858, FBgn0037859" protein_coding_gene "CG14698, CG4695, 34114" "IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set" CG34114 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" viable FBgn0027129 l(3)E3 lethal (3) E3 http://flybase.net/reports/FBgn0027129.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0019912 Ypf1a Yolk protein factor 1a http://flybase.net/reports/FBgn0019912.html gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0043564=Ku70:Ku80 complex "YPF1, p86, YPF1alpha" 16-Dec-15 2015_12 FBgn0043054 Ivk\gag gag http://flybase.net/reports/FBgn0043054.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" You\gag "IPR001878=Zinc finger, CCHC-type" 16-Dec-15 2015_12 FBgn0014955 ealk easterlike http://flybase.net/reports/FBgn0014955.html gene elk 16-Dec-15 2015_12 FBgn0065588 l(2)SH0908 lethal (2) SH0908 http://flybase.net/reports/FBgn0065588.html gene l(2)SH2 0908 16-Dec-15 2015_12 "lethal,recessive" FBgn0052303 tRNA:CR32303 transfer RNA:CR32303 http://flybase.net/reports/FBgn0052303.html FBgn0060271 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002584.trna13-CysGCA, CR32303, chr3L.trna13-CysGCA, tRNA:C:GCA:AE002584-b" CR32303 16-Dec-15 2015_12 FBgn0070006 BG01515 BG01515 http://flybase.net/reports/FBgn0070006.html gene 16-Dec-15 2015_12 stress response defective FBgn0085199 CG34170 http://flybase.net/reports/FBgn0085199.html protein_coding_gene CG34170 16-Dec-15 2015_12 FBgn0004962 l(1)17Ca lethal (1) 17Ca http://flybase.net/reports/FBgn0004962.html gene T13 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" FBgn0035569 CG15876 http://flybase.net/reports/FBgn0035569.html protein_coding_gene 0032879=regulation of localization HL3 IPR007970=Protein of unknown function DUF733 CG15876 16-Dec-15 2015_12 viable FBgn0005748 l(1)TK243 lethal (1) TK243 http://flybase.net/reports/FBgn0005748.html gene l243 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "lamina,eye" FBgn0010024 E(Dl)D72 Enhancer of Delta D72 http://flybase.net/reports/FBgn0010024.html gene 16-Dec-15 2015_12 FBgn0003176 Plexate Plexate http://flybase.net/reports/FBgn0003176.html gene Px 16-Dec-15 2015_12 "lethal,recessive" FBgn0026533 Dek Dek http://flybase.net/reports/FBgn0026533.html "FBgn0010567, FBgn0021980, FBgn0025829, FBgn0046410, FBgn0046411, FBgn0046412" protein_coding_gene 0003677=DNA binding 0006397=mRNA processing "0005654=nucleoplasm, 0005634=nucleus" "anon-WO0172774.191, l(2)04154, lincRNA.S2954, dDEK, dek, anon-WO0172774.194, CG593, DEK, anon-WO0172774.192, l(2)k09907, CG5935, EG:EG0003.6" "IPR014876=DEK, C-terminal, IPR003034=SAP domain, IPR009057=Homeodomain-like" CG5935 16-Dec-15 2015_12 ENSDARG00000070108(zgc:136346)

"viable,lethal,recessive,fertile,male limited,long lived,temperature response defective,female limited,gravitaxis defective" DRSC07418 IE -1.933559469 -1.068475533 -3.017916871 -4.1066307 1.11703303 0.118157197 FBgn0039478 Nep5 Neprilysin 5 http://flybase.net/reports/FBgn0039478.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis 0016021=integral component of membrane "DmeNEP5, nep5, CG6265, NEP5" "IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain" CG6265 16-Dec-15 2015_12 viable FBgn0028626 l(2)01034 lethal (2) 01034 http://flybase.net/reports/FBgn0028626.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028283 l(1)G0414 lethal (1) G0414 http://flybase.net/reports/FBgn0028283.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262698 Su(VGlut)B51 http://flybase.net/reports/FBgn0262698.html gene B51 16-Dec-15 2015_12 FBgn0031606 CG15439 http://flybase.net/reports/FBgn0031606.html protein_coding_gene 0008270=zinc ion binding 0046331=lateral inhibition "IPR001965=Zinc finger, PHD-type, IPR001841=Zinc finger, RING-type, IPR019787=Zinc finger, PHD-finger, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG15439 16-Dec-15 2015_12 ENSDARG00000061458(si:dkeyp-89d7.1) WBGene00013339(Y59A8A.2) ENSXETG00000022249(PHF14) ENSMUSG00000029629(Phf14) ENSG00000106443(PHF14) "viable,fertile,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" DRSC00453 K 0.131049222 -0.288534242 0.246335475 -0.938027636 -0.246309738 1.757252071 FBgn0016967 w::Dmau\w w http://flybase.net/reports/FBgn0016967.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 "eye color defective,visible" pigment cell FBgn0032416 Gr33a Gustatory receptor 33a http://flybase.net/reports/FBgn0032416.html protein_coding_gene 0008527=taste receptor activity "0050909=sensory perception of taste, 0008049=male courtship behavior" "0030424=axon, 0030425=dendrite, 0016021=integral component of membrane, 0044297=cell body" "Gustatory receptor 33C1, GR33a, Gr33C1, CG17213" IPR013604=7TM chemoreceptor CG17213 16-Dec-15 2015_12 "courtship behavior defective,male,neurophysiology defective,taste perception defective,chemosensitive behavior defective,viable" labellar taste bristle FBgn0263337 CR43418 http://flybase.net/reports/FBgn0263337.html non_protein_coding_gene CR43418 16-Dec-15 2015_12 FBgn0013251 E(var)3-5 E(var)3-5 http://flybase.net/reports/FBgn0013251.html gene E-var(3)5 16-Dec-15 2015_12 "suppressor of variegation,dominant,enhancer of variegation" FBgn0030624 CG9106 http://flybase.net/reports/FBgn0030624.html protein_coding_gene CG9106 16-Dec-15 2015_12 FBgn0060545 l(3)S098911b lethal (3) S098911b http://flybase.net/reports/FBgn0060545.html gene 0989/11 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0036807 CG6893 http://flybase.net/reports/FBgn0036807.html protein_coding_gene 0005310=dicarboxylic acid transmembrane transporter activity 0005739=mitochondrion "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG6893 16-Dec-15 2015_12 viable FBgn0036784 CG5103 http://flybase.net/reports/FBgn0036784.html protein_coding_gene 0004802=transketolase activity 0008152=metabolic process "IPR020826=Transketolase binding site, IPR029061=Thiamin diphosphate-binding fold, IPR005474=Transketolase, N-terminal, IPR009014=Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II, IPR005475=Transketolase-like, pyrimidine-binding domain" CG5103 16-Dec-15 2015_12 "ENSDARG00000006019(tkt),ENSDARG00000029689(LOC557518)" "YPR074C(TKL1),YBR117C(TKL2)" WBGene00008506(tkt-1) "ENSXETG00000026656(TTpA007c10.1),ENSXETG00000015654(tkt)" "ENSMUSG00000025519(Tktl2),ENSMUSG00000021957(Tkt),ENSMUSG00000031397(Tktl1)" "ENSG00000163931(TKT),ENSG00000151005(TKTL2)" viable FBgn0052284 CG32284 http://flybase.net/reports/FBgn0052284.html FBgn0063124 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region BcDNA:LP03531 IPR002557=Chitin binding domain CG32284 16-Dec-15 2015_12 viable FBgn0029716 CG3546 http://flybase.net/reports/FBgn0029716.html protein_coding_gene CG3546 16-Dec-15 2015_12 viable FBgn0264604 CR43953 http://flybase.net/reports/FBgn0264604.html non_protein_coding_gene lincRNA.471 CR43953 16-Dec-15 2015_12 FBgn0022760 Wmc2 Wee-Mik-Complementing 2 http://flybase.net/reports/FBgn0022760.html gene WMC2 16-Dec-15 2015_12 FBgn0032994 CG17482 http://flybase.net/reports/FBgn0032994.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001905 l(2)24Dc lethal (2) 24Dc http://flybase.net/reports/FBgn0001905.html gene "l(2)jf1, jf1" 16-Dec-15 2015_12 lethal FBgn0264359 CR43811 http://flybase.net/reports/FBgn0264359.html non_protein_coding_gene "lincRNA.S2724, lincRNA.305" CR43811 16-Dec-15 2015_12 FBgn0050489 Cyp12d1-p Cyp12d1-p http://flybase.net/reports/FBgn0050489.html "FBgn0033576, FBgn0041339" protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0005506=iron ion binding" "0046680=response to DDT, 0055114=oxidation-reduction process, 0017085=response to insecticide" 0005739=mitochondrion "CG18240, cytochrome P450, CYP12D1, Cyp 12d1, 12d1, Cytochrome P450-12d1, CG30489, 12D1, Cyp12d1" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG30489 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" chemical resistant FBgn0260245 GSd453 http://flybase.net/reports/FBgn0260245.html gene 16-Dec-15 2015_12 lethal FBgn0067780 bsl boussole http://flybase.net/reports/FBgn0067780.html gene "0045450=bicoid mRNA localization, 0045451=pole plasm oskar mRNA localization" 16-Dec-15 2015_12 lethal FBgn0036350 CG14111 http://flybase.net/reports/FBgn0036350.html protein_coding_gene CG14111 16-Dec-15 2015_12 viable FBgn0060753 l(3)S064318 lethal (3) S064318 http://flybase.net/reports/FBgn0060753.html gene 0643/18 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001596 l(1)carot14 lethal (1) carot14 http://flybase.net/reports/FBgn0001596.html gene l(1)TW5 16-Dec-15 2015_12 "lethal,recessive,visible,female sterile" "wing,adult abdomen" FBgn0030613 Rab3-GEF Rab3 GDP-GTP exchange factor http://flybase.net/reports/FBgn0030613.html "FBgn0027715, FBgn0043815" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "1902041=regulation of extrinsic apoptotic signaling pathway via death domain receptors, 0051726=regulation of cell cycle, 0016192=vesicle-mediated transport, 0032483=regulation of Rab protein signal transduction, 0007269=neurotransmitter secretion, 0000187=activation of MAPK activity" "0016021=integral component of membrane, 0008021=synaptic vesicle" "rab3-GEF, BEST:GH21304, anon-EST:Posey246, Rab3-GEF, CG5627" "IPR001194=DENN domain, IPR005112=dDENN domain, IPR005113=uDENN domain" CG5627 16-Dec-15 2015_12 ENSDARG00000003495(LOC100150917) WBGene00000086(aex-3) ENSMUSG00000040687(Madd) ENSG00000110514(MADD) "viable,fertile" FBgn0034010 CG8157 http://flybase.net/reports/FBgn0034010.html FBgn0047179 protein_coding_gene BcDNA:RE07473 CG8157 16-Dec-15 2015_12 viable FBgn0264909 CR44100 http://flybase.net/reports/FBgn0264909.html non_protein_coding_gene CR44100 16-Dec-15 2015_12 FBgn0004359 T48 Transcript 48 http://flybase.net/reports/FBgn0004359.html protein_coding_gene 0007370=ventral furrow formation 0016324=apical plasma membrane "transcript-48, t48, Ubx-t48, anon-97D, CG5507, '48' transcript, 48" "IPR009030=Insulin-like growth factor binding protein, N-terminal" CG5507 16-Dec-15 2015_12 "viable,fertile" ventral furrow FBgn0031695 Cyp4ac3 Cyp4ac3 http://flybase.net/reports/FBgn0031695.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG14031, 4ac3, cytochrome P450" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG14031 16-Dec-15 2015_12 YDR402C(DIT2) "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0025158 ms(2)A1 ms(2)A1 http://flybase.net/reports/FBgn0025158.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0003977 vir virilizer http://flybase.net/reports/FBgn0003977.html FBgn0034852 protein_coding_gene 0003676=nucleic acid binding "0007549=dosage compensation, 0007298=border follicle cell migration, 0048024=regulation of mRNA splicing, via spliceosome, 0007539=primary sex determination, soma, 0000375=RNA splicing, via transesterification reactions, 0007530=sex determination" "0005634=nucleus, 0016021=integral component of membrane" "Vir, CG3496" IPR026736=Protein virilizer CG3496 16-Dec-15 2015_12 ENSMUSG00000040720(1110037F02Rik) ENSG00000164944(KIAA1429) "lethal,recessive,wild-type,sex-determination defective,female,heat sensitive,viable,lethal - all die before end of larval stage,some die during larval stage,female sterile,maternal effect,male,male fertile,partially lethal - majority die,visible" "border follicle cell,somatic clone,adult abdomen,heat sensitive,abdominal tergite 6,abdominal tergite 7,oviprotector,female gonopod,anal plate,hypoproct,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0262636 dati datilografo http://flybase.net/reports/FBgn0262636.html "FBgn0083092, FBgn0039905, FBgn0039906" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0031175=neuron projection development, 0016319=mushroom body development, 0045925=positive regulation of female receptivity, 0008344=adult locomotory behavior, 0048699=generation of neurons" "CG2052, dati, DmLin29, Lin29, CG10204, datilografo" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG2052 16-Dec-15 2015_12 WBGene00019751(M03D4.4) FBgn0000290 Cg10AB Collagen-like 10AB http://flybase.net/reports/FBgn0000290.html gene "Cg3, DCg3" 16-Dec-15 2015_12 FBgn0264489 CG43897 http://flybase.net/reports/FBgn0264489.html "FBgn0052050, FBgn0036050, FBgn0053205, FBgn0036049, FBgn0036051, FBgn0052049, FBgn0052051, FBgn0064835, FBgn0064876" protein_coding_gene "0007498=mesoderm development, 0046331=lateral inhibition" "CG32049, CG32050, BcDNA:RE55923, CG14172, CG33205, BcDNA:RH19933, CG32051, CG8154, CG8163" IPR006643=ZASP CG43897 16-Dec-15 2015_12 FBgn0265778 PDZ-GEF PDZ domain-containing guanine nucleotide exchange factor http://flybase.net/reports/FBgn0265778.html "FBgn0069356, FBgn0031798, FBgn0021873, FBgn0265624, FBgn0082671" protein_coding_gene "0017016=Ras GTPase binding, 0005085=guanyl-nucleotide exchange factor activity, 0017034=Rap guanyl-nucleotide exchange factor activity, 0017132=cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity" "0016476=regulation of embryonic cell shape, 0035099=hemocyte migration, 0034333=adherens junction assembly, 0030155=regulation of cell adhesion, 0048477=oogenesis, 0007412=axon target recognition, 0000165=MAPK cascade, 0048749=compound eye development, 0006930=substrate-dependent cell migration, cell extension, 0007391=dorsal closure, 0045314=regulation of compound eye photoreceptor development, 0030718=germ-line stem cell maintenance, 0035211=spermathecum morphogenesis, 0043547=positive regulation of GTPase activity, 0007476=imaginal disc-derived wing morphogenesis, 0016477=cell migration, 0007485=imaginal disc-derived male genitalia development" "0005912=adherens junction, 0016327=apicolateral plasma membrane" "GEF, Dzy, Dizzy, EC2-8, CG9491, D-PDZGEF, PDZ-GEF/Dizzy, Gef26, dizzy, PDF-GEF Dizzy, dzy, l(2)k13720, PDZ-GEF, DGEF, dPDZ-GEF" "IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain, IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR000159=Ras-associating (RA) domain, IPR023578=Ras guanine nucleotide exchange factor domain, IPR014710=RmlC-like jelly roll fold, IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR029071=Ubiquitin-related domain, IPR001478=PDZ domain, IPR019804=Ras guanine-nucleotide exchange factor, conserved site" CG9491 16-Dec-15 2015_12 "ENSDARG00000061459(si:dkey-253i9.4),ENSDARG00000005482(LOC100329945)" WBGene00004254(pxf-1) ENSXETG00000012010() "ENSMUSG00000062232(Rapgef2),ENSMUSG00000037533(Rapgef6)" "ENSG00000109756(RAPGEF2),ENSG00000158987(RAPGEF6)" DRSC03231 E -1.115914075 -0.531928597 -1.770098189 -0.470963788 1.111480823 -0.889726447 FBgn0267180 CR45620 http://flybase.net/reports/FBgn0267180.html non_protein_coding_gene CR45620 16-Dec-15 2015_12 FBgn0020829 l(2)SA "South Amherst, Mass" http://flybase.net/reports/FBgn0020829.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065596 l(2)SH0889 lethal (2) SH0889 http://flybase.net/reports/FBgn0065596.html gene l(2)SH2 0889 16-Dec-15 2015_12 "lethal,recessive" FBgn0004763 l(3)89Cd lethal (3) 89Cd http://flybase.net/reports/FBgn0004763.html gene 16-Dec-15 2015_12 lethal FBgn0043491 flea\polyprotein polyprotein http://flybase.net/reports/FBgn0043491.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0004190=aspartic-type endopeptidase activity" "0015074=DNA integration, 0006508=proteolysis" blastopia\polyprotein "IPR001878=Zinc finger, CCHC-type, IPR021109=Aspartic peptidase domain, IPR001969=Aspartic peptidase, active site, IPR000477=Reverse transcriptase domain, IPR018061=Peptidase A2A, retrovirus RVP subgroup, IPR001584=Integrase, catalytic core, IPR001995=Peptidase A2A, retrovirus, catalytic, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0031678 CG31918 http://flybase.net/reports/FBgn0031678.html "FBgn0051918, FBgn0061966" protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "CG18592, anon-WO0118547.477" "IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR024079=Metallopeptidase, catalytic domain" CG31918 16-Dec-15 2015_12 viable dorsal appendage FBgn0045800 Uhg1 U snoRNA host gene 1 http://flybase.net/reports/FBgn0045800.html "FBgn0040741, FBgn0052886" non_protein_coding_gene "BEST:GM03135, Dros-UHG1, CR32886, CG14486, dUHG1, dUhg1, FBgn0040741" CR32886 16-Dec-15 2015_12 FBgn0264723 CR43991 http://flybase.net/reports/FBgn0264723.html non_protein_coding_gene CG43991 CR43991 16-Dec-15 2015_12 FBgn0005071 fs(2)OW212 female sterile (2) OW212 http://flybase.net/reports/FBgn0005071.html gene 16-Dec-15 2015_12 FBgn0013259 E(var)45 E(var)45 http://flybase.net/reports/FBgn0013259.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0036325 CG10752 http://flybase.net/reports/FBgn0036325.html FBgn0044634 protein_coding_gene anon-WO0140519.236 "IPR011705=BTB/Kelch-associated, IPR011333=POZ domain" CG10752 16-Dec-15 2015_12 viable FBgn0013550 l(3)100Ab lethal (3) 100Ab http://flybase.net/reports/FBgn0013550.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034458 Ir56d Ionotropic receptor 56d http://flybase.net/reports/FBgn0034458.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "IR56d, ionotropic receptor 56d, DmelIR56d, CG15904" CG15904 16-Dec-15 2015_12 viable FBgn0261630 CG42713 http://flybase.net/reports/FBgn0261630.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity DMG4-MB6.chr2L.16.012 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42713 16-Dec-15 2015_12 FBgn0003119 po pale ocelli http://flybase.net/reports/FBgn0003119.html gene 0006727=ommochrome biosynthetic process "do, dilute ocelli" 16-Dec-15 2015_12 ocellus pigment granule FBgn0033782 sug sugarbabe http://flybase.net/reports/FBgn0033782.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "0048009=insulin-like growth factor receptor signaling pathway, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated, 0045893=positive regulation of transcription, DNA-templated, 0042594=response to starvation, 0031670=cellular response to nutrient" 0016607=nuclear speck CG3850 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG3850 16-Dec-15 2015_12 "YPR015C(),YPR013C()" "developmental rate defective,heat sensitive,lethal,male,starvation stress response defective,viable" FBgn0265718 CR44525 http://flybase.net/reports/FBgn0265718.html non_protein_coding_gene "incRNA.462, lincRNA.462" CR44525 16-Dec-15 2015_12 FBgn0039647 CG14509 http://flybase.net/reports/FBgn0039647.html FBgn0039646 protein_coding_gene 0042048=olfactory behavior CG14510 CG14509 16-Dec-15 2015_12 "viable,smell perception defective,fertile" FBgn0259467 C166 http://flybase.net/reports/FBgn0259467.html gene 16-Dec-15 2015_12 visible "wing hair,wing vein" FBgn0002494 l(3)SG54 lethal (3) SG54 http://flybase.net/reports/FBgn0002494.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,heat sensitive,some die during embryonic stage" FBgn0002823 ms(2)38C male sterile (2) 38C http://flybase.net/reports/FBgn0002823.html gene ms 16-Dec-15 2015_12 "male sterile,recessive" FBgn0065637 l(2)SH0765 lethal (2) SH0765 http://flybase.net/reports/FBgn0065637.html gene l(2)SH2 0765 16-Dec-15 2015_12 "lethal,recessive" FBgn0014340 mof males absent on the first http://flybase.net/reports/FBgn0014340.html protein_coding_gene "0046972=histone acetyltransferase activity (H4-K16 specific), 0005515=protein binding, 0003729=mRNA binding, 0003682=chromatin binding, 0004468=lysine N-acetyltransferase activity, acting on acetyl phosphate as donor, 0004402=histone acetyltransferase activity" "0051091=positive regulation of sequence-specific DNA binding transcription factor activity, 0010212=response to ionizing radiation, 0043984=histone H4-K16 acetylation, 0016573=histone acetylation, 0006281=DNA repair, 0018394=peptidyl-lysine acetylation, 0030330=DNA damage response, signal transduction by p53 class mediator, 0007549=dosage compensation, 0071479=cellular response to ionizing radiation, 2000873=regulation of histone H4 acetylation involved in response to DNA damage stimulus, 0009047=dosage compensation by hyperactivation of X chromosome, 0043066=negative regulation of apoptotic process, 0000077=DNA damage checkpoint" "0005667=transcription factor complex, 0005705=polytene chromosome interband, 0000228=nuclear chromosome, 0000805=X chromosome, 0016456=X chromosome located dosage compensation complex, transcription activating, 0005634=nucleus, 0044545=NSL complex, 0072487=MSL complex" "MOF, males absent on first, CG3025, males-absent-on-the-first, Mof, MOF histone acetylase, Males absent on first, dmMOF, Males absent on the first, unnamed, males-absent on the X, dMOF, max" "IPR002717=Histone acetyltransferase domain, MYST-type, IPR025995=RNA binding activity-knot of a chromodomain, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR016181=Acyl-CoA N-acyltransferase" CG3025 16-Dec-15 2015_12 ENSDARG00000027187(myst1) WBGene00010537(mys-2) ENSXETG00000001943(myst1) ENSMUSG00000030801(Myst1) ENSG00000103510(KAT8) larval stage--adult stage "female fertile,non-suppressor of variegation,wild-type,lethal,male,recessive,viable,female,increased cell death,radiation sensitive,partially lethal - majority die,female sterile,short lived,male limited,large body,female limited,decreased cell growth,lethal - all die during larval stage" "heart primordium,eye disc,wing disc,embryonic/larval fat body" FBgn0259171 Pde9 Phosphodiesterase 9 http://flybase.net/reports/FBgn0259171.html "FBgn0052648, FBgn0030424, FBgn0030426, FBgn0030427, FBgn0030428" protein_coding_gene "0004114=3',5'-cyclic-nucleotide phosphodiesterase activity, 0047555=3',5'-cyclic-GMP phosphodiesterase activity" "0009187=cyclic nucleotide metabolic process, 0022008=neurogenesis, 0007165=signal transduction" "CG3765, CG3754, CG32648, CG42276, CG1627, PDE9, CG3761" "IPR003607=HD/PDEase domain, IPR023174=3'5'-cyclic nucleotide phosphodiesterase, conserved site, IPR002073=3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR023088=3'5'-cyclic nucleotide phosphodiesterase" CG42276 16-Dec-15 2015_12 FBgn0038529 CG14323 http://flybase.net/reports/FBgn0038529.html protein_coding_gene CG14323 16-Dec-15 2015_12 viable DRSC14802 E -0.68520201 -0.081526843 1.966632417 0.21844102 -0.279816649 0.157506215 FBgn0050443 Opbp Optix-binding protein http://flybase.net/reports/FBgn0050443.html "FBgn0033080, FBgn0064885" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "Optix binding protein, Obp, OBP, CG30443, BcDNA:RE37461, CG12397" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG30443 16-Dec-15 2015_12 "viable,fertile" FBgn0260375 GSd446 http://flybase.net/reports/FBgn0260375.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0039255 CG13646 http://flybase.net/reports/FBgn0039255.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport "IPR013057=Amino acid transporter, transmembrane domain" CG13646 16-Dec-15 2015_12 "WBGene00012529(Y32F6A.4),WBGene00021156(Y4C6B.2),WBGene00012487(Y18D10A.23),WBGene00019837(R02F2.8),WBGene00017663(F21D12.3),WBGene00022012(Y59H11AR.4)" viable FBgn0025135 su(RpII140Z36)S12 su(RpII140Z36)S12 http://flybase.net/reports/FBgn0025135.html gene Z36[S12] 16-Dec-15 2015_12 FBgn0082999 snoRNA:ë¬28S-1192c snoRNA:ë¬28S-1192c http://flybase.net/reports/FBgn0082999.html snoRNA_gene "psi28S-1192c, CR34595, Psi28S-1192c" CR34595 16-Dec-15 2015_12 FBgn0065639 l(2)SH0762 lethal (2) SH0762 http://flybase.net/reports/FBgn0065639.html gene l(2)SH2 0762 16-Dec-15 2015_12 "lethal,recessive" FBgn0017482 T3dh Type III alcohol dehydrogenase http://flybase.net/reports/FBgn0017482.html protein_coding_gene "0046872=metal ion binding, 0047988=hydroxyacid-oxoacid transhydrogenase activity" "0015993=molecular hydrogen transport, 0055114=oxidation-reduction process" 0005739=mitochondrion CG3425 "IPR001670=Alcohol dehydrogenase, iron-type" CG3425 16-Dec-15 2015_12 ENSDARG00000053518(adhfe1) YGL256W(ADH4) WBGene00012608(Y38F1A.6) ENSXETG00000023251(Q6P371_XENTR) ENSMUSG00000025911(Adhfe1) ENSG00000147576(ADHFE1) "viable,fertile,visible" trichogen cell FBgn0001416 l(1)5CDa lethal (1) 5CDa http://flybase.net/reports/FBgn0001416.html gene "l(1)E12, ts155, l(1)ts155" 16-Dec-15 2015_12 "sterile,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,chemical sensitive" FBgn0085240 CG34211 http://flybase.net/reports/FBgn0085240.html protein_coding_gene CG34211 16-Dec-15 2015_12 FBgn0070030 BG00080 BG00080 http://flybase.net/reports/FBgn0070030.html gene 16-Dec-15 2015_12 "stress response defective,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,sleep defective" FBgn0085292 CG34263 http://flybase.net/reports/FBgn0085292.html protein_coding_gene CG34263 16-Dec-15 2015_12 FBgn0261739 EC4330 http://flybase.net/reports/FBgn0261739.html gene 16-Dec-15 2015_12 female sterile FBgn0083965 CG34129 http://flybase.net/reports/FBgn0083965.html "FBan0006069, FBgn0039418" protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space "SPH192, CG6069" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG34129 16-Dec-15 2015_12 viable FBgn0035933 CG13309 http://flybase.net/reports/FBgn0035933.html protein_coding_gene 0008061=chitin binding "0032504=multicellular organism reproduction, 0006030=chitin metabolic process" "0005576=extracellular region, 0005615=extracellular space" CT32604 IPR002557=Chitin binding domain CG13309 16-Dec-15 2015_12 viable FBgn0020301 fs(3)100C fs(3)100C http://flybase.net/reports/FBgn0020301.html gene fs(100C) 16-Dec-15 2015_12 FBgn0030277 CG1394 http://flybase.net/reports/FBgn0030277.html "FBgn0044700, FBgn0046282" protein_coding_gene "BEST:GH24085, bs30g07.y1, anon-WO0140519.177" CG1394 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004825 fs(2)ltoQE45 female sterile (2) ltoQE45 http://flybase.net/reports/FBgn0004825.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0003710 tipE temperature-induced paralytic E http://flybase.net/reports/FBgn0003710.html protein_coding_gene "0017080=sodium channel regulator activity, 0005248=voltage-gated sodium channel activity" "0002028=regulation of sodium ion transport, 0034605=cellular response to heat, 0045433=male courtship behavior, veined wing generated song production, 0006814=sodium ion transport" "0005887=integral component of plasma membrane, 0005886=plasma membrane" "temperature-induced-paralytic-E, temperature-induced paralysis locus E, tip-E, CG1232, TipE" CG1232 16-Dec-15 2015_12 " embryonic stage , adult stage " " embryonic peripheral nervous system

, leg

, antenna

, antenno-maxillary complex

, adult head

, central nervous system

" "wild-type,paralytic,heat sensitive,chemical resistant,courtship behavior defective,male,recessive,neuroanatomy defective,viable,visible,lethal" "neuromuscular junction & synapse,synapse | ectopic | heat sensitive,trichogen cell" FBgn0001516 l(1)10Fj lethal (1) 10Fj http://flybase.net/reports/FBgn0001516.html gene 16-Dec-15 2015_12 "lethal,polyphasic,recessive,cell lethal,germline clone" FBgn0040334 Tsp3A Tetraspanin 3A http://flybase.net/reports/FBgn0040334.html FBgn0029630 protein_coding_gene "0006909=phagocytosis, 0045747=positive regulation of Notch signaling pathway, 0007298=border follicle cell migration" 0016021=integral component of membrane "Dm.Tsp3A, CG10742, EG:BACR7C10.6, BACR7C10.6, tsp3A" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin" CG10742 16-Dec-15 2015_12 "ENSDARG00000004497(tspan33),ENSDARG00000042189(LOC567512),ENSDARG00000042967(zgc:113223)" ENSMUSG00000001763(Tspan33) ENSG00000158457(TSPAN33) "viable,fertile" "sensory mother cell,somatic clone,supernumerary" FBgn0030415 CG15726 http://flybase.net/reports/FBgn0030415.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263329 CR43410 http://flybase.net/reports/FBgn0263329.html non_protein_coding_gene CR43410 16-Dec-15 2015_12 FBgn0260590 2L3081 http://flybase.net/reports/FBgn0260590.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0035388 CG2162 http://flybase.net/reports/FBgn0035388.html FBgn0027742 protein_coding_gene "0000166=nucleotide binding, 0003676=nucleic acid binding" anon-EST:Posey170 "IPR001374=R3H domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG2162 16-Dec-15 2015_12 WBGene00008622(F09C8.2) ENSMUSG00000025184(D19Ertd386e) ENSG00000104679(R3HCC1) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC08557 I -0.995653385 -1.829900572 -0.127522695 -0.161080206 0.227530834 0.257245196 FBgn0003384 shakA shaking A http://flybase.net/reports/FBgn0003384.html gene 16-Dec-15 2015_12 "hyperactive,courtship behavior defective,heat sensitive,jumping defective,flight defective,uncoordinated,hypoactive" FBgn0053339 CG33339 http://flybase.net/reports/FBgn0053339.html "FBgn0046281, FBgn0039191" protein_coding_gene CG13612 IPR006631=Protein of unknown function DM4/12 CG33339 16-Dec-15 2015_12 FBgn0086883 Pab Pale body http://flybase.net/reports/FBgn0086883.html gene 16-Dec-15 2015_12 "body color defective,dominant,lethal,recessive" "adult cuticle,antenna,tergite" FBgn0036747 CG6052 http://flybase.net/reports/FBgn0036747.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR026082=ABC transporter A, ABCA, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain" CG6052 16-Dec-15 2015_12 ENSDARG00000013500(abca2) "YIL013C(PDR11),YOR011W(AUS1),YNR070W(PDR18),YDR011W(SNQ2),YPL058C(PDR12),YOR328W(PDR10),YOR153W(PDR5),YDR406W(PDR15),YOL075C()" WBGene00000022(abt-4) ENSXETG00000020232(ABCA3) "ENSMUSG00000024130(Abca3),ENSMUSG00000035435(Abca17),ENSMUSG00000054746(Abca15),ENSMUSG00000062017(Abca14),ENSMUSG00000051900(Abca16)" ENSG00000167972(ABCA3) viable FBgn0013322 Pcp82 Pupal-cuticle-protein-82kD http://flybase.net/reports/FBgn0013322.html gene 16-Dec-15 2015_12 FBgn0037976 Tk Tachykinin http://flybase.net/reports/FBgn0037976.html protein_coding_gene "0005184=neuropeptide hormone activity, 0005102=receptor binding, 0071861=tachykinin receptor binding" "0007217=tachykinin receptor signaling pathway, 0007608=sensory perception of smell, 0006629=lipid metabolic process, 0007218=neuropeptide signaling pathway, 0007628=adult walking behavior, 0019236=response to pheromone, 0002121=inter-male aggressive behavior" 0005615=extracellular space "tachykinin-3, TAP-5, Drm-TK-1, TK-1, DTK-1, Drm-TK-3, tachykinin, tachykinin-6, DTK1, DTK, DmTK6, Tyk, Drm-TK-4, tachykinin-like peptide, DTK-2, DTK-5, Dtk, DTK-3, DTK-6, tachykinin-1, preprotachykinin, Drm-TK, CG14734, TK, Drm-TK-6, Tachykinin-related, dtk, Drm-TK-2, DTK-4, Drm-TK-5, neurokinin" CG14734 16-Dec-15 2015_12 "viable,fertile,behavior defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,locomotor behavior defective,female" FBgn0000421 displaced displaced http://flybase.net/reports/FBgn0000421.html gene dd 16-Dec-15 2015_12 "visible,female sterile" "antenna,adult head,eye" FBgn0267710 CR46043 http://flybase.net/reports/FBgn0267710.html non_protein_coding_gene CR46043 16-Dec-15 2015_12 FBgn0031058 CG14227 http://flybase.net/reports/FBgn0031058.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH158 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG14227 16-Dec-15 2015_12 FBgn0039806 CG15545 http://flybase.net/reports/FBgn0039806.html protein_coding_gene CG15545 16-Dec-15 2015_12 FBgn0051488 CG31488 http://flybase.net/reports/FBgn0051488.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040806 CG13456 http://flybase.net/reports/FBgn0040806.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265077 CR44188 http://flybase.net/reports/FBgn0265077.html non_protein_coding_gene CR44188 16-Dec-15 2015_12 FBgn0262653 l(3)ED220-1 http://flybase.net/reports/FBgn0262653.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during P-stage,lethal" FBgn0031985 mon2 http://flybase.net/reports/FBgn0031985.html "FBgn0040956, FBgn0051756" protein_coding_gene "0005519=cytoskeletal regulatory protein binding, 0005086=ARF guanyl-nucleotide exchange factor activity" "0031532=actin cytoskeleton reorganization, 0007318=pole plasm protein localization, 0016192=vesicle-mediated transport, 0015031=protein transport" "0005768=endosome, 0005802=trans-Golgi network, 0005794=Golgi apparatus" "CG31756, CG14276, CG8683, noan, no anchor, Mon2" "IPR026829=Monensin-resistant homologue 2, IPR015403=Domain of unknown function DUF1981, Sec7 associated, IPR016024=Armadillo-type fold" CG8683 16-Dec-15 2015_12 ENSDARG00000063694(LOC100334806) YNL297C(MON2) WBGene00008685(mon-2) ENSXETG00000018796(MON2) ENSMUSG00000034602(Mon2) ENSG00000061987(MON2) "viable,body color defective" mesothoracic tergum FBgn0016887 l(2)39DEl lethal (2) 39DEl http://flybase.net/reports/FBgn0016887.html gene K234 16-Dec-15 2015_12 lethal FBgn0061516 cri criss-cross http://flybase.net/reports/FBgn0061516.html gene 0001700=embryonic development via the syncytial blastoderm cri 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic epidermis,denticle belt" FBgn0032077 CG9515 http://flybase.net/reports/FBgn0032077.html "FBgn0043835, FBgn0053085" protein_coding_gene 0005737=cytoplasm "CG33085, gh06087, BEST:GH06087" "IPR029001=Inosine triphosphate pyrophosphatase-like, IPR003697=Maf-like protein" CG9515 16-Dec-15 2015_12 YOR111W() WBGene00008316(dod-18) "viable,fertile" FBgn0004963 abg ambiguous http://flybase.net/reports/FBgn0004963.html gene "0048477=oogenesis, 0035017=cuticle pattern formation" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,lethal,rescuable maternal effect" "embryonic epidermis,germline clone,embryonic/first instar larval cuticle,ovary" FBgn0262024 CG42835 http://flybase.net/reports/FBgn0262024.html protein_coding_gene CG42835 16-Dec-15 2015_12 FBgn0020226 Calp14B Calpain 14B http://flybase.net/reports/FBgn0020226.html gene 0004198=calcium-dependent cysteine-type endopeptidase activity calpain 16-Dec-15 2015_12 FBgn0031055 et eye transformer http://flybase.net/reports/FBgn0031055.html protein_coding_gene "0004872=receptor activity, 0046982=protein heterodimerization activity, 0004896=cytokine receptor activity" "0042532=negative regulation of tyrosine phosphorylation of STAT protein, 0046426=negative regulation of JAK-STAT cascade, 0042742=defense response to bacterium" 0016020=membrane "Latran, CG14225, lat, ET" "IPR003529=Long hematopoietin receptor, Gp130 family 2, conserved site" CG14225 16-Dec-15 2015_12 "viable,fertile,stress response defective,RU486 conditional" "lamellocyte,wing,eye" FBgn0003679 te tenerchaetae http://flybase.net/reports/FBgn0003679.html gene 16-Dec-15 2015_12 "visible,recessive,viable,good,male,male sterile,female sterile,eye color defective" "macrochaeta,wing,wing vein,pigment cell,eye" FBgn0086061 snoRNA:Or-CD8 http://flybase.net/reports/FBgn0086061.html snoRNA_gene "CR34690, orphan CD8, DmOr_cd8" CR34690 16-Dec-15 2015_12 FBgn0250830 CG12547 http://flybase.net/reports/FBgn0250830.html "FBgn0040521, FBan0012547, FBgn0058277, FBgn0027702" protein_coding_gene "anon-EST:Posey268, CG40277" "IPR012336=Thioredoxin-like fold, IPR013017=NHL repeat, subgroup, IPR011042=Six-bladed beta-propeller, TolB-like, IPR001258=NHL repeat" CG12547 16-Dec-15 2015_12 ENSMUSG00000025078(Nhlrc2) ENSG00000196865(NHLRC2) FBgn0019921 T:nls-Sry-ë« nuclear localisation signal of Sry-ë« http://flybase.net/reports/FBgn0019921.html engineered_tag "T:nls3, nuclear localisation signal 3" 16-Dec-15 2015_12 FBgn0005315 mu-F mutator from Florida http://flybase.net/reports/FBgn0005315.html gene mutability factor from Florida 16-Dec-15 2015_12 FBgn0266916 Cenp-C Centromeric protein-C http://flybase.net/reports/FBgn0266916.html "FBgn0086697, FBgn0051258, FBgn0037598, FBgn0037597, FBgn0002310, FBgn0065118" protein_coding_gene 0003677=DNA binding "0016321=female meiosis chromosome segregation, 0007052=mitotic spindle organization, 0022008=neurogenesis, 0007080=mitotic metaphase plate congression, 0071459=protein localization to chromosome, centromeric region, 0051382=kinetochore assembly, 0090230=regulation of centromere complex assembly, 0034501=protein localization to kinetochore, 0007059=chromosome segregation, 0000022=mitotic spindle elongation" "0000776=kinetochore, 0000775=chromosome, centromeric region, 0000780=condensed nuclear chromosome, centromeric region" "l(3)85Aa, Cenp-C, lethal (3) 85Aa, l(2)SH3 157, centromeric protein C, CENP-C, l(3)SH157, lethal (3) SH157, CG31258, CG11745, CLD1, CG11746, L1, cenp-C, CenpC" "IPR017956=AT hook, DNA-binding motif" CG31258 16-Dec-15 2015_12 DRSC14371 E -1.229021924 -0.012567605 -0.04471976 -1.960457999 -1.057280315 1.08633189 FBgn0037874 Tctp Translationally controlled tumor protein ortholog (H. sapiens) http://flybase.net/reports/FBgn0037874.html protein_coding_gene "0005088=Ras guanyl-nucleotide exchange factor activity, 0005509=calcium ion binding, 0005085=guanyl-nucleotide exchange factor activity" "0045793=positive regulation of cell size, 0006302=double-strand break repair, 0040018=positive regulation of multicellular organism growth, 0031573=intra-S DNA damage checkpoint, 0071480=cellular response to gamma radiation, 0033129=positive regulation of histone phosphorylation, 0007095=mitotic G2 DNA damage checkpoint" "0005886=plasma membrane, 0045298=tubulin complex, 0005700=polytene chromosome, 0005737=cytoplasm, 0005634=nucleus" "dTCTP, TCTP, Translationally Controlled Tumor Protein, Translationally controlled tumor protein, CG4800" "IPR011323=Mss4/translationally controlled tumour-associated TCTP, IPR018103=Translationally controlled tumour protein, conserved site, IPR018105=Translationally controlled tumour protein, IPR011057=Mss4-like" CG4800 16-Dec-15 2015_12 "ENSDARG00000069902(tpt1),ENSDARG00000069891" YKL056C(TMA19) WBGene00009122(tct-1) ENSXETG00000014661(tpt1) "ENSMUSG00000060126(Tpt1),ENSMUSG00000059252(Gm6790)" ENSG00000133112(TPT1) "viable,mitotic cell cycle defective,maternal effect,lethal,recessive,small body,radiation sensitive,DNA repair defective,visible,decreased cell size,decreased cell number,lethal - all die before end of larval stage,some die during third instar larval stage,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,some die during pupal stage" "eye,wing,1st posterior cell,imaginal disc,somatic clone,trichogen cell,mesothoracic tergum" FBgn0267585 CR45923 http://flybase.net/reports/FBgn0267585.html "FBgn0264910, FBgn0032998, FBan0017478, FBgn0058280" non_protein_coding_gene "CR44101, CG40280, CG17478" CR45923 16-Dec-15 2015_12 FBgn0026250 eIF-1A Eukaryotic initiation factor 1A http://flybase.net/reports/FBgn0026250.html "FBgn0025531, FBgn0025959, FBgn0038594, FBgn0062638" protein_coding_gene 0003743=translation initiation factor activity "0006413=translational initiation, 0007052=mitotic spindle organization, 0006909=phagocytosis, 0006412=translation, 0007224=smoothened signaling pathway, 0000022=mitotic spindle elongation" "0005654=nucleoplasm, 0016282=eukaryotic 43S preinitiation complex, 0005829=cytosol" "anon-EST:Liang-2.3, D-eIF4c, group I, CG8053, eIF-4c, clone 2.3, eIF1A, EP935, Eukaryotic initiation factor 4c, D-eIF1A, EP(3)0935, anon-EST:Posey4, lincRNA.S7087, Group I" "IPR012340=Nucleic acid-binding, OB-fold, IPR018104=Translation initiation factor 1A (eIF-1A), conserved site, IPR006196=RNA-binding domain, S1, IF1 type, IPR001253=Translation initiation factor 1A (eIF-1A)" CG8053 16-Dec-15 2015_12 "ENSDARG00000029003(eif1axa),ENSDARG00000057912(eif1axb)" YMR260C(TIF11) WBGene00019162(eif-1.A) ENSXETG00000025347(eif1a) "ENSMUSG00000067194(Eif1ax),ENSMUSG00000057561(Eif1a),ENSMUSG00000079028(Gm2056),ENSMUSG00000079034(Gm8300),ENSMUSG00000072905(Gm5662),ENSMUSG00000072909(Gm16368),ENSMUSG00000079029(Gm2016),ENSMUSG00000079030,ENSMUSG00000071217(Gm4027),ENSMUSG00000079031" "ENSG00000173674(EIF1AX),ENSG00000198692(EIF1AY)" "viable,fertile,lethal,recessive,cell lethalcell lethal,somatic clone" DRSC16937 I -3.735674488 -1.796659258 -0.15675353 -1.300122881 0.70594744 1.456308064 FBgn0058142 CG40142 http://flybase.net/reports/FBgn0058142.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014277 l(2)k16904 lethal (2) k16904 http://flybase.net/reports/FBgn0014277.html gene l(2)169/4 16-Dec-15 2015_12 "lethal,recessive" FBgn0003622 Su(var)2-147 Suppressor of variegation 2-147 http://flybase.net/reports/FBgn0003622.html gene 16-Dec-15 2015_12 FBgn0262385 mir-307a mir-307a stem loop http://flybase.net/reports/FBgn0262385.html "FBgn0067697, FBgn0262206" miRNA_gene "CR42913, mir-307 stem loop, CR33611, miR-307, mir-307, miR-307a, dme-mir-307a" CR42913 16-Dec-15 2015_12 "visible,lethal" wing FBgn0003247 rh roughish http://flybase.net/reports/FBgn0003247.html gene 0048749=compound eye development 16-Dec-15 2015_12 "visible,recessive" "eye disc,ommatidium,eye photoreceptor cell,eye" FBgn0267385 PyK Pyruvate kinase http://flybase.net/reports/FBgn0267385.html "FBgn0003178, FBgn0024583" protein_coding_gene "0004743=pyruvate kinase activity, 0030955=potassium ion binding, 0000287=magnesium ion binding" "0006096=glycolytic process, 0007525=somatic muscle development, 0016310=phosphorylation, 0007520=myoblast fusion, 0009744=response to sucrose, 0006090=pyruvate metabolic process" "0043186=P granule, 0005811=lipid particle, 0005829=cytosol" "Pyk, CG7070, PK, lethal (3) rQ178, PYK, l(3)rQ178, l(3)r[Q178], pyruvate kinase, Pyruvate Kinase" "IPR001697=Pyruvate kinase, IPR011037=Pyruvate kinase-like, insert domain, IPR015793=Pyruvate kinase, barrel, IPR018209=Pyruvate kinase, active site, IPR015795=Pyruvate kinase, C-terminal, IPR015806=Pyruvate kinase, beta-barrel insert domain, IPR015813=Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR015794=Pyruvate kinase, alpha/beta" CG7070 16-Dec-15 2015_12 "ENSDARG00000003933(pkm2a),ENSDARG00000003191(pkm2b)" "YAL038W(CDC19),YOR347C(PYK2)" WBGene00009126(pyk-1) "ENSXETG00000005206(pkm2),ENSXETG00000013164(PKLR)" "ENSMUSG00000032294(Pkm2),ENSMUSG00000041237(Pklr)" "ENSG00000067225(PKM2),ENSG00000143627(PKLR)" FBgn0000241 bw brown http://flybase.net/reports/FBgn0000241.html protein_coding_gene "0005524=ATP binding, 0005395=eye pigment precursor transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0006726=eye pigment biosynthetic process, 0006810=transport, 0006856=eye pigment precursor transport, 0006727=ommochrome biosynthetic process, 0006728=pteridine biosynthetic process, 0007605=sensory perception of sound" "0043190=ATP-binding cassette (ABC) transporter complex, 0005887=integral component of plasma membrane" "Suppressor of white-coral J, Su(w[coJ]), Plum, CG17632, Pm, unnamed, pteridine-modifier, Suppressor of white-coral-2, brow, Su(w[co2]), ptm" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR005284=Pigment precursor permease, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR013525=ABC-2 type transporter" CG17632 16-Dec-15 2015_12 "eye color defective,dominant,chemical resistant,male,auditory perception defective,visible,viable,recessive,wild-type,lethal,fertile,enhancer of variegation" "pigment cell,pigment granule,hemolymph,ocellus,wing,eye" FBgn0267244 CR45684 http://flybase.net/reports/FBgn0267244.html non_protein_coding_gene CR45684 16-Dec-15 2015_12 FBgn0052102 CG32102 http://flybase.net/reports/FBgn0052102.html FBgn0063020 protein_coding_gene BcDNA:RE42781 CG32102 16-Dec-15 2015_12 viable FBgn0003236 reti reticent http://flybase.net/reports/FBgn0003236.html gene ret 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0001876 l(1)XN82b lethal (1) XN82b http://flybase.net/reports/FBgn0001876.html gene 16-Dec-15 2015_12 FBgn0045850 l(4)102Fc lethal (4) 102Fc http://flybase.net/reports/FBgn0045850.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031959 spz3 spatzle 3 http://flybase.net/reports/FBgn0031959.html FBgn0031960 protein_coding_gene 0005121=Toll binding 0008063=Toll signaling pathway 0005576=extracellular region "CG7104, Spz3, CT34263, CG14533, CT21967" IPR029034=Cystine-knot cytokine CG7104 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011446 l(3)neo2 lethal (3) neo2 http://flybase.net/reports/FBgn0011446.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062701 EP1095 EP1095 http://flybase.net/reports/FBgn0062701.html gene EP(2)1095 16-Dec-15 2015_12 FBgn0262997 CR43305 http://flybase.net/reports/FBgn0262997.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0011610 l(1)I33e14 lethal (1) I33e14 http://flybase.net/reports/FBgn0011610.html FBgn0010206 gene l(1)33e14 16-Dec-15 2015_12 lethal FBgn0259597 B0633 http://flybase.net/reports/FBgn0259597.html gene 16-Dec-15 2015_12 visible wing FBgn0262883 CR43238 http://flybase.net/reports/FBgn0262883.html non_protein_coding_gene "chr3R:26,572,448-26,572,516" CR43238 16-Dec-15 2015_12 FBgn0263094 CG43362 http://flybase.net/reports/FBgn0263094.html protein_coding_gene CG43362 16-Dec-15 2015_12 FBgn0066357 l(2)23CDg lethal (2) 23CDg http://flybase.net/reports/FBgn0066357.html gene 16-Dec-15 2015_12 FBgn0035073 CG16896 http://flybase.net/reports/FBgn0035073.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity "IPR000195=Rab-GTPase-TBC domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG16896 16-Dec-15 2015_12 ENSXETG00000023189(wrd67) ENSMUSG00000022364(Wdr67) ENSG00000156787(WDR67) viable FBgn0013657 ms(2)neo2 ms(2)neo2 http://flybase.net/reports/FBgn0013657.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0260740 Grip98 http://flybase.net/reports/FBgn0260740.html protein_coding_gene "Dgrip98, GCP3" 16-Dec-15 2015_12 FBgn0086904 Nacë± Nascent polypeptide associated complex protein alpha subunit http://flybase.net/reports/FBgn0086904.html "FBgn0017565, FBgn0010571" protein_coding_gene 0005515=protein binding "0048477=oogenesis, 0022008=neurogenesis, 0007317=regulation of pole plasm oskar mRNA localization" 0005854=nascent polypeptide-associated complex "alpha-NAC, Alpha NAC, unnamed, NAC, CG8759, NACalpha, l(2)04329, alphaNAC, NAC protein alpha subunit, aic, Nacalpha, lethal (2) 04329" "IPR002715=Nascent polypeptide-associated complex NAC domain, IPR016641=Nascent polypeptide-associated complex subunit alpha" CG8759 16-Dec-15 2015_12 "ENSDARG00000070976,ENSDARG00000005513(naca),ENSDARG00000012347" YHR193C(EGD2) WBGene00022042(Y65B4BR.5) "ENSXETG00000004407(naca),ENSXETG00000023867(NACAD)" "ENSG00000196531(NACA),ENSG00000196861,ENSG00000121089" FBgn0034204 CG10953 http://flybase.net/reports/FBgn0034204.html protein_coding_gene CG10953-PA IPR004011=GYR motif CG10953 16-Dec-15 2015_12 "ENSXETG00000015080(),ENSXETG00000015480(),ENSXETG00000001378(),ENSXETG00000003613(),ENSXETG00000013355(),ENSXETG00000006375(),ENSXETG00000013595(),ENSXETG00000021278(),ENSXETG00000014082(),ENSXETG00000025634(),ENSXETG00000012800(),ENSXETG00000014412(),ENSXETG00000022340(),ENSXETG00000013141()" "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0259238 CG42336 http://flybase.net/reports/FBgn0259238.html "FBgn0033612, FBgn0033613, FBgn0063338" protein_coding_gene "CG13211, CG13210, BcDNA:AT13707" CG42336 16-Dec-15 2015_12 FBgn0030327 FucT6 "ë±1,6-fucosyltransferase" http://flybase.net/reports/FBgn0030327.html FBgn0025708 protein_coding_gene "0008424=glycoprotein 6-alpha-L-fucosyltransferase activity, 0008417=fucosyltransferase activity, 0046921=alpha-(1->6)-fucosyltransferase activity, 0046702=galactoside 6-L-fucosyltransferase activity" "0018279=protein N-linked glycosylation via asparagine, 0046368=GDP-L-fucose metabolic process, 0033578=protein glycosylation in Golgi, 0006486=protein glycosylation" "0030173=integral component of Golgi membrane, 0032580=Golgi cisterna membrane, 0016021=integral component of membrane" "FucT6, CK00490, Dm alpha1,6-FucT, Fuc-TVIII, dalpha6Fut, CG2448, core alpha1,6-fucosyltransferase, BEST:CK00490" "IPR015827=Alpha-(1,6)-fucosyltransferase, eukaryotic type, IPR001452=SH3 domain, IPR027350=Glycosyltransferase family 23 (GT23) domain" CG2448 16-Dec-15 2015_12 ENSDARG00000015449(fut8) WBGene00001508(fut-8) ENSXETG00000007644(Q6NVP8_XENTR) ENSMUSG00000021065(Fut8) ENSG00000033170(FUT8) "viable,fertile,immune response defective" FBgn0265694 CR44501 http://flybase.net/reports/FBgn0265694.html non_protein_coding_gene lincRNA.962 CR44501 16-Dec-15 2015_12 FBgn0281841 T:cic cic fragment http://flybase.net/reports/FBgn0281841.html engineered_tag short motif of Cic 16-Dec-15 2015_12 FBgn0004850 Su(var)204 Suppressor of variegation 204 http://flybase.net/reports/FBgn0004850.html gene 204 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0011849 tRNA:E4:56Fb transfer RNA:glu4:56Fb http://flybase.net/reports/FBgn0011849.html "FBgn0003771, FBgn0011846, FBgn0050455, FBgn0060240" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033459=GAA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:E:TTC:AE002787-b, tRNA:glu4:56Fb, AE002787.trna5-GluTTC, tRNA:E4, CR30455, tRNA:Glu, glu-tRNA-4, chr2R.trna63-GluTTC" CR30455 16-Dec-15 2015_12 FBgn0033540 Elp2 Elongator complex protein 2 http://flybase.net/reports/FBgn0033540.html protein_coding_gene 0061133=endopeptidase activator activity "0043248=proteasome assembly, 0006368=transcription elongation from RNA polymerase II promoter" 0000502=proteasome complex "StIP, elp-2, Stip, D-elp2, CG1187, CG11887" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site" CG11887 16-Dec-15 2015_12 ENSDARG00000017199(si:dkey-190l1.1) YGR200C(ELP2) WBGene00013738(elpc-2) ENSXETG00000018920(statip1) ENSMUSG00000024271(Elp2) ENSG00000134759(ELP2) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0029039 l(2)G56 lethal (2) G56 http://flybase.net/reports/FBgn0029039.html gene G56 16-Dec-15 2015_12 "lethal,recessive" FBgn0266745 CG45218 http://flybase.net/reports/FBgn0266745.html protein_coding_gene CG45218 16-Dec-15 2015_12 FBgn0261926 CG42793 http://flybase.net/reports/FBgn0261926.html protein_coding_gene CG43203 16-Dec-15 2015_12 FBgn0033043 Or42b Odorant receptor 42b http://flybase.net/reports/FBgn0033043.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "41E.1, CG12754, 42b, DOR118, OR42b" "IPR004117=Olfactory receptor, Drosophila" CG12754 16-Dec-15 2015_12 "viable,fertile,smell perception defective" FBgn0030091 CG7065 http://flybase.net/reports/FBgn0030091.html protein_coding_gene CG7065 16-Dec-15 2015_12 "lethal,some die during pupal stage,viable" DRSC25280 K 0.304504596 1.188708194 1.426216408 1.069094513 1.723976147 0.825441875 FBgn0265015 S042938 http://flybase.net/reports/FBgn0265015.html gene 16-Dec-15 2015_12 FBgn0084606 1038 1038 http://flybase.net/reports/FBgn0084606.html gene 16-Dec-15 2015_12 FBgn0026636 l(2)k15801 lethal (2) k15801 http://flybase.net/reports/FBgn0026636.html gene 16-Dec-15 2015_12 lethal FBgn0015217 E(var)53E Enhancer of variegation 53E http://flybase.net/reports/FBgn0015217.html gene E(var)2-53E 16-Dec-15 2015_12 "female sterile,recessive,enhancer of variegation,dominant" FBgn0267531 CR45871 http://flybase.net/reports/FBgn0267531.html non_protein_coding_gene CR45871 16-Dec-15 2015_12 FBgn0002731 mfs(3)G male female sterile G http://flybase.net/reports/FBgn0002731.html gene fs(3)4 16-Dec-15 2015_12 "female sterile,male sterile,viable,poor,visible" "egg chamber,adult fat body,metathoracic tibia,metathoracic tarsal segment" FBgn0036157 CG7560 http://flybase.net/reports/FBgn0036157.html FBgn0043820 protein_coding_gene 0004489=methylenetetrahydrofolate reductase (NAD(P)H) activity "0006555=methionine metabolic process, 0055114=oxidation-reduction process" "gh18008, BEST:GH18008" "IPR003171=Methylenetetrahydrofolate reductase, IPR029041=FAD-linked oxidoreductase-like" CG7560 16-Dec-15 2015_12 viable FBgn0033481 CG12920 http://flybase.net/reports/FBgn0033481.html protein_coding_gene CG12920 16-Dec-15 2015_12 viable FBgn0264517 CR43916 http://flybase.net/reports/FBgn0264517.html non_protein_coding_gene CR43916 16-Dec-15 2015_12 FBgn0000803 fs(1)de14 female sterile (1) defective eggs 14 http://flybase.net/reports/FBgn0000803.html gene de14 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion,endochorion" FBgn0264702 CR43971 http://flybase.net/reports/FBgn0264702.html non_protein_coding_gene CR43971 16-Dec-15 2015_12 FBgn0083997 CG41355 http://flybase.net/reports/FBgn0083997.html FBan0041355 protein_coding_gene 16-Dec-15 2015_12 FBgn0004073 fs(2)mel7 female sterile (2) maternal effect lethal 7 http://flybase.net/reports/FBgn0004073.html gene Mel 7 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,semidominant,some die during embryonic stage" "embryonic/larval posterior spiracle,maternal effect" FBgn0016043 lup-1 loop unfolding protein-1 http://flybase.net/reports/FBgn0016043.html gene 0007288=sperm axoneme assembly "ms(3)HB223, 155-34" 16-Dec-15 2015_12 "male sterile,recessive,female semi-sterile,female sterile" "Y chromosome loop,spermatid axoneme,axonemal dynein complex,axonemal microtubule | ectopic,axonemal microtubule | supernumerary" FBgn0052946 CG32946 http://flybase.net/reports/FBgn0052946.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085812 CR41601 http://flybase.net/reports/FBgn0085812.html FBan0041601 non_protein_coding_gene CR41601 16-Dec-15 2015_12 FBgn0010832 l(3)04069b lethal (3) 04069b http://flybase.net/reports/FBgn0010832.html gene l(3)04069 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" "crystal cell,plasmatocyte" FBgn0051014 PH4ë±SG1 prolyl-4-hydroxylase-alpha SG1 http://flybase.net/reports/FBgn0051014.html FBgn0039781 protein_coding_gene "0005506=iron ion binding, 0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity" "0007435=salivary gland morphogenesis, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" "PHalphaSG1, CG15542, PH4alphaSG1, SG1, Prolyl 4-hydroxylase alpha salivary gland 1, SG specific ER protein prolyl-4-hydroxylase, alphaSG1, CG31014, Ph4alphaSG1" "IPR011990=Tetratricopeptide-like helical domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123=Oxoglutarate/iron-dependent dioxygenase" CG31014 16-Dec-15 2015_12 viable FBgn0010563 l(2)04008 lethal (2) 04008 http://flybase.net/reports/FBgn0010563.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267204 CR45644 http://flybase.net/reports/FBgn0267204.html non_protein_coding_gene CR45644 16-Dec-15 2015_12 FBgn0085479 CG34450 http://flybase.net/reports/FBgn0085479.html "FBan0032705, FBgn0030129, FBgn0003058, FBgn0030128, FBgn0030127, FBgn0052705" protein_coding_gene "CG12136, CG32705" CG34450 16-Dec-15 2015_12 FBgn0005107 gustF gustatory-defective F http://flybase.net/reports/FBgn0005107.html gene 16-Dec-15 2015_12 taste perception defective taste bristle FBgn0265300 CR44273 http://flybase.net/reports/FBgn0265300.html non_protein_coding_gene CR44273 16-Dec-15 2015_12 FBgn0000013 abd abdominal http://flybase.net/reports/FBgn0000013.html gene 0007423=sensory organ development "a(3)26, a-3" 16-Dec-15 2015_12 "visible,semidominant" "tergite,sternite" FBgn0036427 CG4613 http://flybase.net/reports/FBgn0036427.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP40 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG4613 16-Dec-15 2015_12 WBGene00006619(try-1) "ENSXETG00000017962(),ENSXETG00000016040(TMPRSS6),ENSXETG00000027846(),ENSXETG00000015131(),ENSXETG00000016870(HPN),ENSXETG00000027104(),ENSXETG00000010125(TMPRSS13),ENSXETG00000007294(TMPRSS12)" "ENSMUSG00000024034(Tmprss3),ENSMUSG00000000385(Tmprss2),ENSMUSG00000032268(Tmprss5),ENSMUSG00000001249(Hpn)" viable FBgn0051213 CG31213 http://flybase.net/reports/FBgn0051213.html "FBgn0038757, FBgn0038758" protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances" 0006810=transport "0016020=membrane, 0016021=integral component of membrane" "CG11460, CG4794" "IPR026082=ABC transporter A, ABCA, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG31213 16-Dec-15 2015_12 viable FBgn0265526 CR44376 http://flybase.net/reports/FBgn0265526.html non_protein_coding_gene CR44376 16-Dec-15 2015_12 FBgn0265533 CR44383 http://flybase.net/reports/FBgn0265533.html pseudogene_attribute CR44383 16-Dec-15 2015_12 FBgn0064169 l(3)64.63 lethal (3) 64.63 http://flybase.net/reports/FBgn0064169.html gene 0007300=ovarian nurse cell to oocyte transport 16-Dec-15 2015_12 lethal FBgn0259943 Ttd8 TRPL translocation defect 8 http://flybase.net/reports/FBgn0259943.html protein_coding_gene TRPL translocation defect 8 16-Dec-15 2015_12 FBgn0060695 l(3)S073006 lethal (3) S073006 http://flybase.net/reports/FBgn0060695.html gene 0730/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0005207 l(3)e lethal on ebony http://flybase.net/reports/FBgn0005207.html gene lethal (3) with ebony 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0034687 CG11475 http://flybase.net/reports/FBgn0034687.html protein_coding_gene IPR002791=Domain of unknown function DUF89 CG11475 16-Dec-15 2015_12 ENSDARG00000055676(zgc:110816) YMR027W() WBGene00009290(F31D4.2) ENSXETG00000008483(BC075279.1) ENSMUSG00000061759(1700052N19Rik) ENSG00000146476(C6orf211) viable FBgn0038484 CG5246 http://flybase.net/reports/FBgn0038484.html FBgn0063109 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BcDNA:LP06628, SP96" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG5246 16-Dec-15 2015_12 viable FBgn0024294 Spn43Aa Serpin 43Aa http://flybase.net/reports/FBgn0024294.html "FBgn0033144, FBgn0063809" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis, 0010951=negative regulation of endopeptidase activity" 0005615=extracellular space "Spn43 Aa, Ser1, Serine protease inhibitor 43Aa, SER1, anon-WO0118057.1, Spn43A, CG12172, Serine protease inhibitor 1" "IPR000215=Serpin family, IPR023796=Serpin domain" CG12172 16-Dec-15 2015_12 viable FBgn0001166 gy gouty legs http://flybase.net/reports/FBgn0001166.html gene gouty 16-Dec-15 2015_12 "viable,fertile,visible" "leg,metatarsus & metathoracic leg" FBgn0024863 l(3)05471 lethal (3) 05471 http://flybase.net/reports/FBgn0024863.html gene 5471 16-Dec-15 2015_12 "lethal,recessive" FBgn0035063 CG3594 http://flybase.net/reports/FBgn0035063.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" "Exu-associated protein, cg3594, Eap, CG3594" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG3594 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0024637 l(2)k13531 lethal (2) k13531 http://flybase.net/reports/FBgn0024637.html gene 135/31 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0014310 l(3)ry102 lethal (3) ry102 http://flybase.net/reports/FBgn0014310.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011254 ms(3)98B male sterile (3) 98B http://flybase.net/reports/FBgn0011254.html gene 0007286=spermatid development ms(3)06302 16-Dec-15 2015_12 "male sterile,recessive,male semi-sterile" FBgn0016796 exl exu-like http://flybase.net/reports/FBgn0016796.html gene Exl 16-Dec-15 2015_12 FBgn0263854 l(3)YD1073 http://flybase.net/reports/FBgn0263854.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261840 pre-mod(mdg4)-X http://flybase.net/reports/FBgn0261840.html protein_coding_gene CG42772 "IPR007588=Zinc finger, FLYWCH-type" CG42772 16-Dec-15 2015_12 FBgn0033921 tej tejas http://flybase.net/reports/FBgn0033921.html FBgn0025259 protein_coding_gene "0030717=karyosome formation, 0010529=negative regulation of transposition" 0043186=P granule "unnamed, anon-fast-evolving-1D11, anon-EST:fe1D11, CG8589, Tej, Tejas" "IPR002999=Tudor domain, IPR025605=OST-HTH/LOTUS domain" CG8589 16-Dec-15 2015_12 ENSDARG00000071450(tdrd5) ENSMUSG00000060985(Tdrd5) ENSG00000162782(TDRD5) "female sterile,recessive,viable,female sterile germline-dependent,female semi-sterile" FBgn0262057 Spn77Ba Serpin 77Ba http://flybase.net/reports/FBgn0262057.html "FBgn0036968, FBgn0029023" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0035009=negative regulation of melanization defense response, 0045861=negative regulation of proteolysis" 0005615=extracellular space "unnamed, spn77Ba, l(3)77ABi, Q0E8C8_DROME, CG6680, lethal (3) 77ABi" "IPR023796=Serpin domain, IPR000215=Serpin family" CG6680 16-Dec-15 2015_12 FBgn0003062 Fib Fibrillarin http://flybase.net/reports/FBgn0003062.html protein_coding_gene "0008168=methyltransferase activity, 0003723=RNA binding" "0008033=tRNA processing, 0006364=rRNA processing, 0051297=centrosome organization, 0009267=cellular response to starvation, 0006396=RNA processing" "0005730=nucleolus, 0015030=Cajal body, 0030532=small nuclear ribonucleoprotein complex, 0001651=dense fibrillar component, 0005732=small nucleolar ribonucleoprotein complex" "GCR-6, GCR6, Pen59C5, Fibri, fib, fibrillarin, pen59C5, CG9888" "IPR020813=Fibrillarin, conserved site, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR000692=Fibrillarin" CG9888 16-Dec-15 2015_12 ENSDARG00000053912(fbl) YDL014W(NOP1) WBGene00001423(fib-1) ENSXETG00000017830(fbl) ENSMUSG00000046865(Fbl) ENSG00000105202(FBL) female sterile FBgn0054047 CR34047 http://flybase.net/reports/FBgn0054047.html FBgn0082657 non_protein_coding_gene "CG34047, unnamed, HDC08545, BP1083" CR34047 16-Dec-15 2015_12 FBgn0263315 Ubi::Ecol\birA http://flybase.net/reports/FBgn0263315.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0022113 l(2)k06904 lethal (2) k06904 http://flybase.net/reports/FBgn0022113.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001685 l(1)ESHS6 lethal (1) ESHS6 http://flybase.net/reports/FBgn0001685.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264997 CR44148 http://flybase.net/reports/FBgn0264997.html non_protein_coding_gene CR44148 16-Dec-15 2015_12 FBgn0008641 94Che 94Che http://flybase.net/reports/FBgn0008641.html gene 16-Dec-15 2015_12 FBgn0005069 fs(2)OW210 female sterile (2) OW210 http://flybase.net/reports/FBgn0005069.html gene 16-Dec-15 2015_12 FBgn0045823 vsg visgun http://flybase.net/reports/FBgn0045823.html "FBgn0036034, FBgn0062200" protein_coding_gene "0008355=olfactory learning, 0007611=learning or memory, 0007476=imaginal disc-derived wing morphogenesis, 0007616=long-term memory, 0048149=behavioral response to ethanol, 0042127=regulation of cell proliferation, 0032504=multicellular organism reproduction" "0098549=somatic ring canal, 0035324=female germline ring canal, 0031410=cytoplasmic vesicle" "BEST:GH15083, Visgun, Vsg, GH15083, anon-WO0118547.164, FBgn0045823, endolyn, CG16707" IPR007947=CD164-related protein CG16707 16-Dec-15 2015_12 ENSDARG00000013628(cd164) ENSMUSG00000019818(Cd164) ENSG00000135535(CD164) "viable,memory defective,chemical sensitive,fertile,melanotic mass phenotype" melanotic mass FBgn0044108 E(rst)C384 E(rst)C384 http://flybase.net/reports/FBgn0044108.html gene 0001745=compound eye morphogenesis C384 16-Dec-15 2015_12 viable eye FBgn0002747 min mini http://flybase.net/reports/FBgn0002747.html gene mi 16-Dec-15 2015_12 FBgn0263114 CG43371 http://flybase.net/reports/FBgn0263114.html protein_coding_gene CG43371 16-Dec-15 2015_12 FBgn0053421 5SrRNA:CR33421 5SrRNA:CR33421 http://flybase.net/reports/FBgn0053421.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33421 CR33421 16-Dec-15 2015_12 FBgn0085620 CG41332 http://flybase.net/reports/FBgn0085620.html FBan0041332 protein_coding_gene 16-Dec-15 2015_12 FBgn0034861 CG9815 http://flybase.net/reports/FBgn0034861.html protein_coding_gene CG9815 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0017390 l(1)15Da lethal (1) 15Da http://flybase.net/reports/FBgn0017390.html gene 16-Dec-15 2015_12 lethal FBgn0026337 Su(tor)2-341-39 Su(tor)2-341-39 http://flybase.net/reports/FBgn0026337.html gene 16-Dec-15 2015_12 FBgn0020324 anon-7H1 anon-7H1 http://flybase.net/reports/FBgn0020324.html gene "7H1, unnamed" 16-Dec-15 2015_12 FBgn0038266 CG3610 http://flybase.net/reports/FBgn0038266.html protein_coding_gene CG3610 16-Dec-15 2015_12 viable FBgn0031778 CR9162 http://flybase.net/reports/FBgn0031778.html non_protein_coding_gene CG9162 CR9162 16-Dec-15 2015_12 "viable,fertile" FBgn0064177 l(1)CB-6411-3 lethal (1) CB-6411-3 http://flybase.net/reports/FBgn0064177.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036713 Mip Myoinhibiting peptide precursor http://flybase.net/reports/FBgn0036713.html protein_coding_gene "0001664=G-protein coupled receptor binding, 0016085=myoinhibitory hormone activity, 0005179=hormone activity, 0005184=neuropeptide hormone activity, 0016087=ecdysiostatic hormone activity" "0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway" 0005615=extracellular space "DmMIP3, AST-B, Drm-MIP-2, Drm-MIP-3, DmMIP1, Drostatin-B5, mip, MIP-4, Drostatin-B3, CG6456, allatostatin-B, Allatostatin cricket-type, Mip-like peptide, Drostatin-B1, Drm-MIP, MIP-1, allatostatin (B-type), Allostatin B, myoinhibitory peptide, MIP-3, DmMIP4, DAP-B, drostatin-B2, AstB-1, Myoinhibiting peptide, AstB, myoinhibiting peptide, ASB, allatostatin B-1, myoinhibiting peptide precursor, MIP-5, Drm-MIP-4, MIP-2, DmMIP5, MIP, Mioinhibiting Peptide Precursor, Allatostatin B, allatostatin B, Drostatin-B2, Drm-MIP-1, Ast-B, DmMIP2, allatostatin-B1, Drostatin-B4, Drm-MIP-5" CG6456 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0259614 B2032 http://flybase.net/reports/FBgn0259614.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin bristle,tarsal segment" FBgn0035000 CG13578 http://flybase.net/reports/FBgn0035000.html protein_coding_gene CG13578 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0020550 fs(2)35Ed fs(2)35Ed http://flybase.net/reports/FBgn0020550.html gene 16-Dec-15 2015_12 FBgn0020495 D2 D2 http://flybase.net/reports/FBgn0020495.html gene 16-Dec-15 2015_12 FBgn0029703 CG12692 http://flybase.net/reports/FBgn0029703.html protein_coding_gene IPR011705=BTB/Kelch-associated CG12692 16-Dec-15 2015_12 viable FBgn0014145 deg degarni http://flybase.net/reports/FBgn0014145.html gene 16-Dec-15 2015_12 "viable,visible" "macrochaeta,microchaeta,sensillum campaniformium & wing,macrochaeta & leg,chemosensory sensory organ & proboscis" FBgn0051023 tRNA:CR31023 transfer RNA:CR31023 http://flybase.net/reports/FBgn0051023.html FBgn0060149 tRNA_gene 0033419=CUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:L:TAG:AE002708-a, chr3R.trna38-LeuTAG, AE002708.trna32-LeuTAG, CR31023" CR31023 16-Dec-15 2015_12 FBgn0016760 Ybb Y-bobbed http://flybase.net/reports/FBgn0016760.html rRNA_gene "0022627=cytosolic small ribosomal subunit, 0022625=cytosolic large ribosomal subunit" "rRNA, Y,rDNA, bobbed, NO, Y rDNA, bb, bb[Y], rDNA, nucleolus organizer" 16-Dec-15 2015_12 male fertile FBgn0051076 CG31076 http://flybase.net/reports/FBgn0051076.html FBgn0039468 protein_coding_gene "CG6309, CT19744" IPR001611=Leucine-rich repeat CG31076 16-Dec-15 2015_12 ENSDARG00000057166(c10orf11) ENSXETG00000009871(C10orf11) ENSMUSG00000063458(1700112E06Rik) ENSG00000148655(C10orf11) "viable,body color defective" mesothoracic tergum FBgn0263884 l(3)A42 http://flybase.net/reports/FBgn0263884.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0036486 Msh6 Msh6 http://flybase.net/reports/FBgn0036486.html protein_coding_gene "0032138=single base insertion or deletion binding, 0008094=DNA-dependent ATPase activity, 0003684=damaged DNA binding, 0000400=four-way junction DNA binding, 0005524=ATP binding, 0032137=guanine/thymine mispair binding" "0009411=response to UV, 0007131=reciprocal meiotic recombination, 0006301=postreplication repair, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0006281=DNA repair, 0000710=meiotic mismatch repair, 0045910=negative regulation of DNA recombination, 0043570=maintenance of DNA repeat elements" "0000228=nuclear chromosome, 0032301=MutSalpha complex" "CG7003, Msh6" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007696=DNA mismatch repair protein MutS, core, IPR007695=DNA mismatch repair protein MutS-like, N-terminal, IPR000432=DNA mismatch repair protein MutS, C-terminal, IPR007860=DNA mismatch repair protein MutS, connector domain, IPR015536=DNA mismatch repair protein MutS-homologue MSH6, IPR007861=DNA mismatch repair protein MutS, clamp, IPR016151=DNA mismatch repair protein MutS, N-terminal" CG7003 16-Dec-15 2015_12 ENSDARG00000011666(msh6) YDR097C(MSH6) WBGene00003422(msh-6) ENSXETG00000022635(MSH6) ENSMUSG00000005370(Msh6) ENSG00000116062(MSH6) "viable,fertile" FBgn0262391 mir-184 mir-184 stem loop http://flybase.net/reports/FBgn0262391.html "FBgn0067726, FBgn0067725, FBgn0262218" miRNA_gene "0007310=oocyte dorsal/ventral axis specification, 0008595=anterior/posterior axis specification, embryo" "mir-184*, 184, dme-mir-184, mir-184, miR-184, CR33576, CR42925, CR33577, dme-miR-184-3p, miR-184S, dme-miR-184, miR-184*, mir-184S" CR42925 16-Dec-15 2015_12 FBgn0261733 EC4056 http://flybase.net/reports/FBgn0261733.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0067753 l(1)G0135 lethal (1) G0135 http://flybase.net/reports/FBgn0067753.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265582 CR44409 http://flybase.net/reports/FBgn0265582.html non_protein_coding_gene CR44409 16-Dec-15 2015_12 FBgn0000526 dusky-body dusky body http://flybase.net/reports/FBgn0000526.html gene dyb 16-Dec-15 2015_12 "viable,male fertile,female sterile,eye color defective,body color defective" "adult thorax,pigment cell,eye,wing" FBgn0065240 l(2)SH2156 lethal (2) SH2156 http://flybase.net/reports/FBgn0065240.html gene l(2)SH2 2156 16-Dec-15 2015_12 "lethal,recessive" FBgn0013524 l(2)23AB2 lethal (2) 23AB2 http://flybase.net/reports/FBgn0013524.html gene l(2)23Ae 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,lethal" FBgn0038203 Or88a Odorant receptor 88a http://flybase.net/reports/FBgn0038203.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DmOr88a, or88a, DOR99, 88A.1, CG14360, 88a" "IPR004117=Olfactory receptor, Drosophila" CG14360 16-Dec-15 2015_12 viable FBgn0069342 TAHRE\gag gag http://flybase.net/reports/FBgn0069342.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "GAG, TAHRE gag" "IPR001878=Zinc finger, CCHC-type, IPR006579=Pre-C2HC domain" 16-Dec-15 2015_12 FBgn0003933 snRNA:U5:14B small nuclear RNA U5 at 14B http://flybase.net/reports/FBgn0003933.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "K2, snRNA[[3]], dU5, snRNA:U5, snRNA4, U5 snRNA 14B, U5 snRNA, U5, small nuclear RNA U5, 14B U5, U5 small nuclear RNA, U5snRNA14B, U5-14B, CR32914, U5var:14B, U5snRNA, snRNA3, U5:14B" CR32914 16-Dec-15 2015_12 FBgn0262006 CG42824 http://flybase.net/reports/FBgn0262006.html FBgn0054053 protein_coding_gene "CG34053, HDC14119" CG42824 16-Dec-15 2015_12 FBgn0263970 CR43724 http://flybase.net/reports/FBgn0263970.html non_protein_coding_gene lincRNA.263 CR43724 16-Dec-15 2015_12 FBgn0250738 l(3)S026909 lethal (3) S026909 http://flybase.net/reports/FBgn0250738.html gene l(3)s026909 16-Dec-15 2015_12 lethal FBgn0262561 Xanthias\polyprotein http://flybase.net/reports/FBgn0262561.html transposable_element_gene polyprotein 16-Dec-15 2015_12 FBgn0020849 if::mew if::mew http://flybase.net/reports/FBgn0020849.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0041237 Gr58c Gustatory receptor 58c http://flybase.net/reports/FBgn0041237.html FBgn0034675 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 58A.3, GR58A.3, 58A.3, GR58c, 58A3, CG13491, Gr58A3" IPR013604=7TM chemoreceptor CG13491 16-Dec-15 2015_12 viable DRSC04136 I 1.637733002 0.410606826 0.530800863 0.5626311 -0.488423637 -0.91337785 FBgn0263384 CR43436 http://flybase.net/reports/FBgn0263384.html non_protein_coding_gene CR43436 16-Dec-15 2015_12 FBgn0086712 Egm Enigma http://flybase.net/reports/FBgn0086712.html "FBgn0033637, FBgn0021848, FBgn0019818" protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0004466=long-chain-acyl-CoA dehydrogenase activity" "1900408=negative regulation of cellular response to oxidative stress, 0032504=multicellular organism reproduction, 0034976=response to endoplasmic reticulum stress, 0001745=compound eye morphogenesis, 0006635=fatty acid beta-oxidation, 0055088=lipid homeostasis" "0005615=extracellular space, 0005739=mitochondrion" "egm, l(2)k14708, enigma, CG9006, Enigma, lethal (2) k14708, Acyl CoA DH" "IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal" CG9006 16-Dec-15 2015_12 DRSC22860 E -0.262340114 1.107950714 2.136550482 1.636922164 0.718444034 0.707057362 FBgn0020931 Est-E Est-E http://flybase.net/reports/FBgn0020931.html gene 0052689=carboxylic ester hydrolase activity 16-Dec-15 2015_12 FBgn0030017 CG2278 http://flybase.net/reports/FBgn0030017.html protein_coding_gene CG2278 16-Dec-15 2015_12 viable FBgn0036714 CG7692 http://flybase.net/reports/FBgn0036714.html protein_coding_gene CG7692 16-Dec-15 2015_12 "viable,fertile" FBgn0069130 mei(2)yh217 mei(2)yh217 http://flybase.net/reports/FBgn0069130.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "female sterile,meiotic cell cycle defective,male,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0267705 CR46038 http://flybase.net/reports/FBgn0267705.html non_protein_coding_gene CR46038 16-Dec-15 2015_12 FBgn0259269 EP-493 http://flybase.net/reports/FBgn0259269.html gene 16-Dec-15 2015_12 visible wing FBgn0051473 CG31473 http://flybase.net/reports/FBgn0051473.html FBgn0037522 protein_coding_gene "0004733=pyridoxamine-phosphate oxidase activity, 0010181=FMN binding" "0008615=pyridoxine biosynthetic process, 0055114=oxidation-reduction process" CG2649 "IPR012349=FMN-binding split barrel, IPR000659=Pyridoxamine 5'-phosphate oxidase, IPR011576=Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain" CG31473 16-Dec-15 2015_12 viable FBgn0051269 CG31269 http://flybase.net/reports/FBgn0051269.html FBgn0038480 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG5233, SP126" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG31269 16-Dec-15 2015_12 viable FBgn0060596 l(3)S092012b lethal (3) S092012b http://flybase.net/reports/FBgn0060596.html gene 0920/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0000209 Bpt Blackpatch http://flybase.net/reports/FBgn0000209.html gene 16-Dec-15 2015_12 "male sterile,recessive,female sterile,partially lethal - majority die,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" eye FBgn0051161 CG31161 http://flybase.net/reports/FBgn0051161.html FBgn0038995 protein_coding_gene CG6943 CG31161 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC25099 K -0.408154239 -0.501008354 0.604084125 -0.375322223 -1.508690417 -0.082845739 FBgn0027180 l(2)60A-N lethal (2) 60A-N http://flybase.net/reports/FBgn0027180.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0065117 l(3)SH158 lethal (3) SH158 http://flybase.net/reports/FBgn0065117.html gene l(2)SH3 158 16-Dec-15 2015_12 "lethal,recessive" FBgn0003226 re-b reduced eyes b http://flybase.net/reports/FBgn0003226.html gene reduced eyes-b 16-Dec-15 2015_12 "ommatidium,eye" FBgn0060535 l(3)S100502b lethal (3) S100502b http://flybase.net/reports/FBgn0060535.html gene 1005/02 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0013681 mt:ND3 mitochondrial NADH-ubiquinone oxidoreductase chain 3 http://flybase.net/reports/FBgn0013681.html FBgn0002867 protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0055114=oxidation-reduction process "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "ND3, nad3, NADH3, CG34076, URF3" "IPR000440=NADH:ubiquinone/plastoquinone oxidoreductase, chain 3" CG34076 16-Dec-15 2015_12 ENSDARG00000063914 WBGene00010966(MTCE.34) ENSMUSG00000064360 ENSG00000198840 FBgn0041092 tai taiman http://flybase.net/reports/FBgn0041092.html "FBgn0010485, FBgn0022157, FBgn0024593, FBgn0032102, FBgn0032103, FBgn0045313" protein_coding_gene "0003713=transcription coactivator activity, 0030374=ligand-dependent nuclear receptor transcription coactivator activity, 0046983=protein dimerization activity, 0035258=steroid hormone receptor binding" "0048675=axon extension, 0060250=germ-line stem-cell niche homeostasis, 0006355=regulation of transcription, DNA-templated, 0007298=border follicle cell migration" "0005634=nucleus, 0008230=ecdysone receptor holocomplex" "Taiman, Drosophila Amplified in breast cancer-1, CG13109, l(2)k05802, DmTaiman, l(2)k05809, 58/2, CG18494, Tai, DAIB1, NEST:bs13g05, EP(2)2630, l(2)01351, TAI, bs13g05.y1" "IPR017426=Nuclear receptor coactivator, IPR000014=PAS domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG13109 16-Dec-15 2015_12 "ENSXETG00000003480(ncoa3),ENSXETG00000015926(NCOA2),ENSXETG00000021173(NCOA1)" adult stage follicle cell

"neuroanatomy defective,somatic clone,lethal,recessive,maternal effect,sleep defective,lethal - all die before end of pupal stage,some die during pupal stage,smell perception defective,female limited,gravitaxis defective" "axon | somatic clone | third instar larval stage,border follicle cell,female germline stem cell,supernumerary,somatic clone,imaginal disc,germarium cap cell,embryonic/first instar larval cuticle,maternal effect,escort stem cell,germline cell,heat sensitive" FBgn0034707 MED16 Mediator complex subunit 16 http://flybase.net/reports/FBgn0034707.html protein_coding_gene "0003712=transcription cofactor activity, 0001104=RNA polymerase II transcription cofactor activity" "0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex" "CG5465, Trap95, Sin4/TRAP95, Med16, med16, dTRAP95" "IPR021665=Mediator complex, subunit Med16, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG5465 16-Dec-15 2015_12 ENSDARG00000040779 ENSXETG00000021641(MED16) ENSMUSG00000013833(Med16) ENSG00000175221(MED16) viable DRSC26633 EK -0.216323112 -0.212411918 -1.604794216 0.820954838 1.223349538 3.473917134 FBgn0038219 CG14839 http://flybase.net/reports/FBgn0038219.html protein_coding_gene IPR007999=Protein of unknown function DUF745 CG14839 16-Dec-15 2015_12 FBgn0002391 l(3)93Dh lethal (3) 93Dh http://flybase.net/reports/FBgn0002391.html gene "l(3)er16, er16" 16-Dec-15 2015_12 "lethal,recessive" FBgn0038972 CG7054 http://flybase.net/reports/FBgn0038972.html protein_coding_gene 0008429=phosphatidylethanolamine binding IPR008914=Phosphatidylethanolamine-binding protein PEBP CG7054 16-Dec-15 2015_12 "YLR179C(),YLR178C(TFS1)" "viable,visible" trichogen cell DRSC16185 K 0.026247332 0.174391091 0.392094207 0.43711184 0.421263102 1.78836673 FBgn0004450 stripes stripes http://flybase.net/reports/FBgn0004450.html gene str 16-Dec-15 2015_12 FBgn0260298 GSd416 http://flybase.net/reports/FBgn0260298.html gene 16-Dec-15 2015_12 lethal FBgn0039088 CG10164 http://flybase.net/reports/FBgn0039088.html FBgn0045427 protein_coding_gene NEST:bs02f09 CG10164 16-Dec-15 2015_12 "neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell" FBgn0010071 Ma-dominigene Ma dominigene http://flybase.net/reports/FBgn0010071.html gene Ma 16-Dec-15 2015_12 FBgn0030581 CG14408 http://flybase.net/reports/FBgn0030581.html protein_coding_gene 0017124=SH3 domain binding IPR007940=SH3-binding 5 CG14408 16-Dec-15 2015_12 WBGene00019365(K03E6.7) ENSXETG00000020349(SH3BP5L) FBgn0000937 fs(2)A7 female sterile (2) A7 http://flybase.net/reports/FBgn0000937.html gene 16-Dec-15 2015_12 "female sterile,recessive,mitotic cell cycle defective" female reproductive system FBgn0060432 l(3)S125815 lethal (3) S125815 http://flybase.net/reports/FBgn0060432.html gene 1258/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0016848 l(1)N29 lethal (1) N29 http://flybase.net/reports/FBgn0016848.html gene N29 16-Dec-15 2015_12 "lethal,recessive" FBgn0262620 CR43144 http://flybase.net/reports/FBgn0262620.html non_protein_coding_gene "CG43144, lincRNA.217" CR43144 16-Dec-15 2015_12 FBgn0051627 CG31627 http://flybase.net/reports/FBgn0051627.html FBgn0045399 protein_coding_gene NEST:bs05g10 IPR006578=MADF domain CG31627 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0030653 CG7860 http://flybase.net/reports/FBgn0030653.html protein_coding_gene "0004067=asparaginase activity, 0003948=N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity" "0033345=asparagine catabolic process via L-aspartate, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" 0005737=cytoplasm "IPR000246=Peptidase T2, asparaginase 2, IPR029055=Nucleophile aminohydrolases, N-terminal" CG7860 16-Dec-15 2015_12 "ENSDARG00000021681(zgc:103568),ENSDARG00000002219" "ENSXETG00000004452(),ENSXETG00000002310(ASRGL1)" ENSMUSG00000024654(Asrgl1) ENSG00000162174(ASRGL1) "viable,lethal" FBgn0265516 Atal Atal http://flybase.net/reports/FBgn0265516.html gene 16-Dec-15 2015_12 "female semi-sterile,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0015941 fs(3)820 fs(3)820 http://flybase.net/reports/FBgn0015941.html gene 16-Dec-15 2015_12 "female sterile,mitotic cell cycle defective" FBgn0036831 CG6839 http://flybase.net/reports/FBgn0036831.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0016787=hydrolase activity" "IPR020821=Extracellular Endonuclease, subunit A, IPR001604=DNA/RNA non-specific endonuclease" CG6839 16-Dec-15 2015_12 "ENSDARG00000063613,ENSDARG00000071216,ENSDARG00000071224(si:ch211-133n4.4),ENSDARG00000071223(zgc:158445),ENSDARG00000063044,ENSDARG00000068523,ENSDARG00000069190(zgc:172339),ENSDARG00000068065,ENSDARG00000061611(LOC556323),ENSDARG00000060913,ENSDARG00000061822,ENSDARG00000070242(zgc:171534)" viable FBgn0016033 lnp larval nonphototactic http://flybase.net/reports/FBgn0016033.html gene 16-Dec-15 2015_12 FBgn0065449 l(2)SH1404 lethal (2) SH1404 http://flybase.net/reports/FBgn0065449.html gene l(2)SH2 1404 16-Dec-15 2015_12 "lethal,recessive" FBgn0265924 CR44713 http://flybase.net/reports/FBgn0265924.html non_protein_coding_gene CR44713 16-Dec-15 2015_12 FBgn0263986 cd cardinal http://flybase.net/reports/FBgn0263986.html "FBgn0000272, FBgn0039005" protein_coding_gene "0004601=peroxidase activity, 0020037=heme binding" "1901216=positive regulation of neuron death, 0070189=kynurenine metabolic process, 0006979=response to oxidative stress, 0055114=oxidation-reduction process, 0006727=ommochrome biosynthetic process, 0060967=negative regulation of gene silencing by RNA" 0005764=lysosome CG6969 "IPR010255=Haem peroxidase, IPR019791=Haem peroxidase, animal" CG6969 16-Dec-15 2015_12 "ENSDARG00000033280(LOC569363),ENSDARG00000019521(mpx),ENSDARG00000012535" "WBGene00015841(C16C8.2),WBGene00009897(F49E12.1)" ENSXETG00000006966(TPO) "ENSMUSG00000009350(Mpo),ENSMUSG00000052234(Epx),ENSMUSG00000009356(Lpo),ENSMUSG00000020673(Tpo)" ENSG00000115705(TPO) FBgn0000259 CkIIë_ Casein kinase II ë_ subunit http://flybase.net/reports/FBgn0000259.html FBgn0027953 protein_coding_gene "0019887=protein kinase regulator activity, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0007310=oocyte dorsal/ventral axis specification, 0045475=locomotor rhythm, 0008062=eclosion rhythm, 0007623=circadian rhythm, 0060810=intracellular mRNA localization involved in pattern specification process, 0006468=protein phosphorylation, 0007622=rhythmic behavior, 0009267=cellular response to starvation, 0016319=mushroom body development, 0022008=neurogenesis" "0005829=cytosol, 0005737=cytoplasm, 0005634=nucleus, 0005956=protein kinase CK2 complex" "dCK2beta, Ck2beta, Andante, CCK2, CKIIb, DmCK2beta, dCKII beta, casein kinase 2, CK II, Ckiibeta, CkII-beta, casein kinase 2 regulatory subunit, CK-II beta, CK-2, CKII-beta1, KC2B_DROME, CK-IIbeta, ck2beta, DmCKIIbeta, casein kinase II beta, CKII, CKIIbeta, dCKII, CK2beta, Casein kinase II beta subunit, mbu, CK2 (beta subunit), CkIIbeta, DmCkIIbeta, CK2, Casein kinase II, mushroom bodies undersized, betaCK2, Ds cas kin, Cask-II-b, CKII beta, Ck-IIbeta, CkIIbeta1, CK2-beta, casein kinase II, And, CG15224, CkII" "IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR000704=Casein kinase II, regulatory subunit" CG15224 16-Dec-15 2015_12 ENSDARG00000046112 YOR039W(CKB2) WBGene00002196(kin-10) ENSXETG00000027935(csnk2b) ENSMUSG00000024387(Csnk2b) "ENSG00000206406,ENSG00000204435(CSNK2B),ENSG00000206300" "circadian rhythm defective,viable,female sterile,partially,male sterile,neuroanatomy defective,visible,lethal,recessive,behavior defective,semidominant,eclosion rhythm defective,locomotor rhythm defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during pupal stage,circadian behavior defective" "Kenyon cell,calyx of adult mushroom body,adult mushroom body,synapse,neuromuscular junction,wing vein,peripheral nervous system,longitudinal connective,ventral nerve cord commissure,synapse | somatic clone,neuromuscular junction | somatic clone,chorion | maternal effect,embryonic/larval neuroblast,ganglion mother cell" FBgn0033074 tomboy40 tomboy40 http://flybase.net/reports/FBgn0033074.html protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0055085=transmembrane transport, 0006626=protein targeting to mitochondrion" "0005742=mitochondrial outer membrane translocase complex, 0005739=mitochondrion" "CG8330, Tomboy40, dtomboy40" "IPR027246=Eukaryotic porin/Tom40, IPR023614=Porin domain" CG8330 16-Dec-15 2015_12 "ENSDARG00000018425(tomm40),ENSDARG00000036721(tomm40l)" YMR203W(TOM40) WBGene00007686(tomm-40) ENSXETG00000019319(tomm40) "ENSMUSG00000002984(Tomm40),ENSMUSG00000005674(Tomm40l)" "ENSG00000130204(TOMM40),ENSG00000158882(TOMM40L)" "viable,visible,lethal" trichogen cell FBgn0020313 anon-9C1 anon-9C1 http://flybase.net/reports/FBgn0020313.html gene 9C1 16-Dec-15 2015_12 FBgn0044394 Scim34 Sensitized chromosome inheritance modifier 34 http://flybase.net/reports/FBgn0044394.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0044093 E(rst)D187 E(rst)D187 http://flybase.net/reports/FBgn0044093.html gene 0001745=compound eye morphogenesis D187 16-Dec-15 2015_12 viable FBgn0250871 pot papillote http://flybase.net/reports/FBgn0250871.html "FBgn0025738, FBgn0030355" protein_coding_gene "0008362=chitin-based embryonic cuticle biosynthetic process, 0008039=synaptic target recognition, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0040005=chitin-based cuticle attachment to epithelium" 0045177=apical part of cell CG2467 IPR001507=Zona pellucida domain CG2467 16-Dec-15 2015_12 FBgn0267891 CR46179 http://flybase.net/reports/FBgn0267891.html pseudogene_attribute CG12717-related CR46179 16-Dec-15 2015_12 FBgn0046642 anon-38D.3 anon-38D.3 http://flybase.net/reports/FBgn0046642.html gene 38D.3 16-Dec-15 2015_12 FBgn0030590 CG9518 http://flybase.net/reports/FBgn0030590.html protein_coding_gene "0008812=choline dehydrogenase activity, 0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity" "0046331=lateral inhibition, 0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process, 0034976=response to endoplasmic reticulum stress" Dm GMCzeta1 "IPR012132=Glucose-methanol-choline oxidoreductase, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal" CG9518 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0039859 CG11539 http://flybase.net/reports/FBgn0039859.html protein_coding_gene 0008080=N-acetyltransferase activity 0016573=histone acetylation NAT9 "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG11539 16-Dec-15 2015_12 "ENSDARG00000071425(LOC100004826),ENSDARG00000067631" WBGene00022055(Y67D2.5) ENSMUSG00000015542(Nat9) ENSG00000109065(NAT9) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0058176 CG40176 http://flybase.net/reports/FBgn0058176.html protein_coding_gene 16-Dec-15 2015_12 FBgn0050029 CR30029 http://flybase.net/reports/FBgn0050029.html "FBgn0085255, FBgn0033595, FBgn0063116" pseudogene_attribute "BcDNA:LP05669, CG30029, CG34226, CG18337" CR30029 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" DRSC06724 I 1.870999871 -0.459854274 0.238191942 0.616532021 -1.102323571 -0.936770881 FBgn0004050 z zeste http://flybase.net/reports/FBgn0004050.html "FBtr0070435, FBpp0070419" protein_coding_gene "0005515=protein binding, 0043565=sequence-specific DNA binding, 0003677=DNA binding" "0031937=positive regulation of chromatin silencing, 0010628=positive regulation of gene expression, 0006355=regulation of transcription, DNA-templated, 0045893=positive regulation of transcription, DNA-templated, 0006727=ommochrome biosynthetic process" "0005705=polytene chromosome interband, 0005725=intercalary heterochromatin, 0035102=PRC1 complex, 0005634=nucleus" "CG7803, en-bx, Z, EG:BACH59J11.3, enhancer-of-bithorax, Zeste, ZESTE, e(bx)" IPR028002=Myb/SANT-like DNA-binding domain CG7803 16-Dec-15 2015_12 " larval stage | late third instar larval stage--prepupal stage , embryonic stage | stage >=9 , larval stage | early third instar larval stage , adult stage , pharate adult stage , embryonic stage -- adult stage , pupal stage , larval stage | third instar stage 2--P " " ring gland

, organism

, embryonic/larval digestive system | restricted

, gonad

, adult muscle system | restricted

, larval central nervous system

, embryonic/larval salivary gland

, antenna

, adult abdomen

, imaginal disc

, Malpighian tubule

, adult brain

" "viable,visible,dominant,wild-type,eye color defective,recessive,lethal" "eye,pigment cell" FBgn0000605 E(var)c101 Enhancer of variegation c101 http://flybase.net/reports/FBgn0000605.html gene "E-var(3)1, E(var)c[101]" 16-Dec-15 2015_12 "enhancer of variegation,dominant,viable,female fertile,male fertile" FBgn0069158 mcl(3)Z2138 mcl(3)Z2138 http://flybase.net/reports/FBgn0069158.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0085468 ND-MWFE NADH dehydrogenase (ubiquinone) MWFE subunit http://flybase.net/reports/FBgn0085468.html "FBgn0061377, FBgn0033795, FBgn0050057, FBgn0033797" protein_coding_gene 0005747=mitochondrial respiratory chain complex I "CG30057, NADH ubiquinone oxidoreductase MWFE, lethal (2) c00093, CG13328, l(2)c00093, CG34439, BcDNA:RH49308, CG17054" "IPR017384=NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1" CG34439 16-Dec-15 2015_12 WBGene00009294(F31D4.9) "lethal,recessive" FBgn0261439 SdhA "Succinate dehydrogenase, subunit A (flavoprotein)" http://flybase.net/reports/FBgn0261439.html "FBgn0003347, FBgn0017539" protein_coding_gene "0008177=succinate dehydrogenase (ubiquinone) activity, 0050660=flavin adenine dinucleotide binding, 0004776=succinate-CoA ligase (GDP-forming) activity" "0022900=electron transport chain, 0006099=tricarboxylic acid cycle" "0005739=mitochondrion, 0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)" "SDH, Sdh A, Succinate dehydrogenase [ubiquinone] flavoprotein subunit, Succinate dehydrogenase A, Succinate dehydrogenase, CG17246, Scs-fp, succinate dehydrogenase, Succinate dehydrogenase Flavoprotein subunit, scs-fp, Succinate dehydrogenase Flavoprotein, succinate dehydrogenase flavoprotein subunit, Sdha, succinyl CoA synthetase flavoprotein subunit of complex II, COMPLEX II: flavoprotein subunit, sdh, Sdh, DHSA, Succinyl coenzyme A synthetase flavoprotein subunit, SUCCINYL COENZIME A SYNTHETASE FLAVOPROTEIN SUBUNIT" "IPR015939=Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal, IPR011281=Succinate dehydrogenase, flavoprotein subunit, IPR003953=FAD-dependent oxidoreductase 2, FAD binding domain, IPR027477=Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain, IPR014006=Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, IPR003952=Fumarate reductase/succinate dehydrogenase, FAD-binding site" CG17246 16-Dec-15 2015_12 ENSDARG00000016721(sdha) "YKL148C(SDH1),YJL045W()" "WBGene00015391(sdha-1),WBGene00016392(sdha-2)" ENSXETG00000023408(SDHA) ENSMUSG00000021577(Sdha) "ENSG00000073578(SDHA),ENSG00000214135" DRSC07547 K 0.481089811 0.281303705 0.38404312 0.469883919 0.229441572 1.642228504 FBgn0001737 l(1)HM7 lethal (1) HM7 http://flybase.net/reports/FBgn0001737.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0044349 ftz-f1::Hsap\NR5A1 NR5A1 http://flybase.net/reports/FBgn0044349.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0004952 1688-10Eb 1.688 satellite-related 10Eb http://flybase.net/reports/FBgn0004952.html repeat_region "1.688, 1688-10E[p]" 16-Dec-15 2015_12 FBgn0037326 CG14669 http://flybase.net/reports/FBgn0037326.html protein_coding_gene 0005525=GTP binding 0007264=small GTPase mediated signal transduction 0016020=membrane Q9VNB7 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020849=Small GTPase superfamily, Ras type, IPR001806=Small GTPase superfamily" CG14669 16-Dec-15 2015_12 "viable,fertile" DRSC12255 I -0.034507484 1.706376879 1.404762645 -0.663469201 0.344725916 0.685751255 FBgn0065557 l(2)SH1000 lethal (2) SH1000 http://flybase.net/reports/FBgn0065557.html gene l(2)SH2 1000 16-Dec-15 2015_12 "lethal,recessive" FBgn0085572 CG41246 http://flybase.net/reports/FBgn0085572.html FBan0041246 protein_coding_gene 16-Dec-15 2015_12 FBgn0013234 E(var)188 E(var)188 http://flybase.net/reports/FBgn0013234.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0026349 Su(dalyh)22C6 Su(dalyh)22C6 http://flybase.net/reports/FBgn0026349.html gene Su(da[lyh]) 16-Dec-15 2015_12 FBgn0060794 l(3)S058412 lethal (3) S058412 http://flybase.net/reports/FBgn0060794.html gene 0584/12 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027155 l(3)31-1 lethal (3) 31-1 http://flybase.net/reports/FBgn0027155.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0022707 Agi Aryl glucosidase incognita http://flybase.net/reports/FBgn0022707.html gene "0004558=alpha-1,4-glucosidase activity" AGI 16-Dec-15 2015_12 "electrophoretic variant,fast,slow" FBgn0030271 CG15202 http://flybase.net/reports/FBgn0030271.html FBgn0063250 protein_coding_gene 0005615=extracellular space "BcDNA:GH13342, DIGF-4" IPR029277=Single domain Von Willebrand factor type C domain CG15202 16-Dec-15 2015_12 viable FBgn0043353 EP3104 EP3104 http://flybase.net/reports/FBgn0043353.html gene 16-Dec-15 2015_12 visible "eye,dorsocentral bristle,scutellar bristle,trichogen cell,ectopic,tormogen cell" FBgn0263755 Su(var)3-9 Suppressor of variegation 3-9 http://flybase.net/reports/FBgn0263755.html "FBgn0003600, FBgn0003624, FBgn0004560, FBgn0014846, FBgn0263739" protein_coding_gene "0003682=chromatin binding, 0046974=histone methyltransferase activity (H3-K9 specific), 0042054=histone methyltransferase activity, 0008270=zinc ion binding" "0048477=oogenesis, 0006325=chromatin organization, 0006306=DNA methylation, 2001229=negative regulation of response to gamma radiation, 0031507=heterochromatin assembly, 0030702=chromatin silencing at centromere, 0016570=histone modification, 0051567=histone H3-K9 methylation, 0048132=female germ-line stem cell asymmetric division, 0016571=histone methylation, 0006342=chromatin silencing, 0070868=heterochromatin organization involved in chromatin silencing, 0016458=gene silencing, 0006348=chromatin silencing at telomere, 0051276=chromosome organization" "0000792=heterochromatin, 0000775=chromosome, centromeric region, 0005701=polytene chromosome chromocenter, 0005634=nucleus" "Su(var), Su(var)328, Suppressor of variegation 306, Su(var)3-9, Suvar39, Su(var) 3-9, Suv 3-9, pitkin, Suppressor of variegation 328, CG43664, Suvar(3)9, Su(Var)3-9, SUV39, caa56376 Suvar39 Dm, ptn, Su(var)3-902, Su(var)306, Su-var(3)902, Su-var(3)9, E(var)3-2, su(var)3-9, dSu(var)3-9, Suvar3-9, CG6476, Su(VAR)3-9, Enhancer of variegation 3-2, dSU(VAR)3-9, histone methyltransferase, Su(var)310, SUV39H1, SU(VAR)3-9, Suppressor of variegation 310, SuVar3-9" "IPR023780=Chromo domain, IPR003606=Pre-SET zinc-binding sub-group, IPR007728=Pre-SET domain, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like, IPR001214=SET domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003616=Post-SET domain, IPR011381=Histone H3-K9 methyltransferase, IPR023779=Chromo domain, conserved site" CG43664 16-Dec-15 2015_12 "suppressor of variegation,dominant,non-suppressor of variegation,viable,enhancer of variegation,recessive,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,syncytial blastoderm embryo,chromatin | maternal effect,dorsal bridge,oocyte nucleus,nurse cell & nucleus,follicle cell,ventral arm of pharyngeal sclerite,dorsal arm of pharyngeal sclerite,polytene chromosome chromocenter,polytene chromosome" FBgn0267765 CR46096 http://flybase.net/reports/FBgn0267765.html non_protein_coding_gene CR46096 16-Dec-15 2015_12 FBgn0085573 CG41247 http://flybase.net/reports/FBgn0085573.html FBan0041247 protein_coding_gene 16-Dec-15 2015_12 FBgn0025702 Srpk79D Serine-arginine protein kinase at 79D http://flybase.net/reports/FBgn0025702.html "FBgn0037157, FBgn0037158" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0048789=cytoskeletal matrix organization at active zone, 0007268=synaptic transmission, 0042742=defense response to bacterium, 0006468=protein phosphorylation" 0048786=presynaptic active zone "SRPK, Srpk79D, CK01209, SRPK1, CG9085, atc, air traffic controller, srpk79D, serine-arginine protein kinase at 79D, CG11489, BEST:CK01209" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG11489 16-Dec-15 2015_12 YMR216C(SKY1) WBGene00004980(spk-1) "flight defective,recessive,locomotor behavior defective,short lived,neuroanatomy defective,viable,neurophysiology defective,fertile" "axon,neuron" FBgn0052580 Muc14A Mucin 14A http://flybase.net/reports/FBgn0052580.html protein_coding_gene 0005201=extracellular matrix structural constituent 0031012=extracellular matrix "CG32580, Muc14A" CG32580 16-Dec-15 2015_12 "viable,fertile" FBgn0000812 fs(1)K93 female sterile (1) K93 http://flybase.net/reports/FBgn0000812.html gene 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0263492 CR43481 http://flybase.net/reports/FBgn0263492.html non_protein_coding_gene CR43481 16-Dec-15 2015_12 FBgn0025751 l(3)93Dl lethal (3) 93Dl http://flybase.net/reports/FBgn0025751.html gene "unnamed, E23" 16-Dec-15 2015_12 "lethal,recessive" FBgn0035711 CG8519 http://flybase.net/reports/FBgn0035711.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" 0007264=small GTPase mediated signal transduction 0016020=membrane "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020849=Small GTPase superfamily, Ras type" CG8519 16-Dec-15 2015_12 "ENSDARG00000015611(rasl11b),ENSDARG00000046013(zgc:110179)" viable FBgn0005738 l(1)TK228 lethal (1) TK228 http://flybase.net/reports/FBgn0005738.html gene l228 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0003992 vst vestar http://flybase.net/reports/FBgn0003992.html gene 16-Dec-15 2015_12 "viable,poor,female sterile" "wing,eye" FBgn0260329 GSd220 http://flybase.net/reports/FBgn0260329.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0003711 tipF temperature-induced paralytic F http://flybase.net/reports/FBgn0003711.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0259562 B2015 http://flybase.net/reports/FBgn0259562.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment" FBgn0000862 fs(1)M56 female sterile (1) M56 http://flybase.net/reports/FBgn0000862.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" egg FBgn0016721 Reg-7 Rhythmically expressed gene 7 http://flybase.net/reports/FBgn0016721.html gene "Dreg-7, Drosophila Rhythmically expressed gene 7" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " adult head

FBgn0038806 CG5412 http://flybase.net/reports/FBgn0038806.html protein_coding_gene "IPR005645=Serine hydrolase FSH, IPR029058=Alpha/Beta hydrolase fold" CG5412 16-Dec-15 2015_12 ENSDARG00000035277(zgc:110011) "YOR280C(FSH3),YMR222C(FSH2),YHR049W(FSH1)" WBGene00007730(C25G4.2) ENSXETG00000023819(OVCA2) ENSMUSG00000038268(Ovca2) ENSG00000214014(OVCA2) "visible,partially lethal - majority die,some die during pharate adult stage,lethal" "mesothoracic tergum,embryonic/larval brain" FBgn0024857 l(3)96Be lethal (3) 96Be http://flybase.net/reports/FBgn0024857.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267647 CR45985 http://flybase.net/reports/FBgn0267647.html non_protein_coding_gene CR45985 16-Dec-15 2015_12 FBgn0005255 l(3)SG74 lethal (3) SG74 http://flybase.net/reports/FBgn0005255.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030824 CG5070 http://flybase.net/reports/FBgn0030824.html protein_coding_gene CG5070 16-Dec-15 2015_12 "viable,visible" "trichogen cell,supernumerary" FBgn0266787 CR45252 http://flybase.net/reports/FBgn0266787.html non_protein_coding_gene CR45252 16-Dec-15 2015_12 FBgn0083018 snoRNA:ë¬18S-841b snoRNA:ë¬18S-841b http://flybase.net/reports/FBgn0083018.html snoRNA_gene "chr2R:16837876..16838002, psi18S-841b, CR34551, Psi18S-841b" CR34551 16-Dec-15 2015_12 FBgn0014985 l(2)46Da lethal (2) 46Da http://flybase.net/reports/FBgn0014985.html gene "Group VII, VII" 16-Dec-15 2015_12 lethal FBgn0060815 l(3)S052904 lethal (3) S052904 http://flybase.net/reports/FBgn0060815.html gene 0529/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0038014 CG10041 http://flybase.net/reports/FBgn0038014.html protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space SP178 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG10041 16-Dec-15 2015_12 viable FBgn0019777 l(1)318 lethal (1) 318 http://flybase.net/reports/FBgn0019777.html gene 16-Dec-15 2015_12 "lethal,partially,recessive" FBgn0036545 GXIVsPLA2 GXIVsPLA2 http://flybase.net/reports/FBgn0036545.html protein_coding_gene "0004623=phospholipase A2 activity, 0005509=calcium ion binding" "0006644=phospholipid metabolic process, 0016042=lipid catabolic process" 0005576=extracellular region "CG17035, GXIVsPLA" "IPR010711=Phospholipase A2, group XII secretory, IPR013090=Phospholipase A2, active site, IPR016090=Phospholipase A2 domain" CG17035 16-Dec-15 2015_12 ENSDARG00000070454(zgc:162119) "ENSXETG00000006155(pla2g12b),ENSXETG00000024112(pla2g12a)" "ENSMUSG00000027999(Pla2g12a),ENSMUSG00000009646(Pla2g12b)" "ENSG00000123739(PLA2G12A),ENSG00000138308(PLA2G12B)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033369 CG8197 http://flybase.net/reports/FBgn0033369.html protein_coding_gene 0022008=neurogenesis CG8197 16-Dec-15 2015_12 ENSDARG00000062235(LOC556175) "ENSXETG00000009217(LRRC34),ENSXETG00000011065(C14orf166B)" ENSMUSG00000027702(Lrrc34) "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0051431 CG31431 http://flybase.net/reports/FBgn0051431.html FBgn0038911 protein_coding_gene 0005007=fibroblast growth factor-activated receptor activity 0008543=fibroblast growth factor receptor signaling pathway 0016021=integral component of membrane "CG13414, CT32770" "IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set" CG31431 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" FBgn0262764 Mst77Y-15ë¬ Male-specific pseudogene 77Y 15 http://flybase.net/reports/FBgn0262764.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0025395 CG18838 http://flybase.net/reports/FBgn0025395.html FBgn0042161 protein_coding_gene EG:196F3.1 16-Dec-15 2015_12 FBgn0032167 CG5853 http://flybase.net/reports/FBgn0032167.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0006909=phagocytosis 0043190=ATP-binding cassette (ABC) transporter complex "IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site" CG5853 16-Dec-15 2015_12 ENSXETG00000021581(ABCG4) "viable,lethal" FBgn0035601 Uev1A Ubiquitin-conjugating enzyme variant 1A http://flybase.net/reports/FBgn0035601.html protein_coding_gene "0061630=ubiquitin protein ligase activity, 0031624=ubiquitin conjugating enzyme binding" 0000209=protein polyubiquitination 0035370=UBC13-UEV1A complex "uev1a, DmUEV, UEV, dUev1A, UEV1a, Uev1A, dUEV1a, Uev1a, UEV1A, dUEV1A, CG10640" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG10640 16-Dec-15 2015_12 "ENSDARG00000041875,ENSDARG00000028198(ube2v2)" YGL087C(MMS2) WBGene00006730(uev-1) "ENSXETG00000027365(),ENSXETG00000004856(ube2v1)" "ENSMUSG00000078923(Ube2v1),ENSMUSG00000022674(Ube2v2),ENSMUSG00000027694,ENSMUSG00000060811" ENSG00000169139(UBE2V2) "lethal,lethal - all die before end of pupal stage,viable" FBgn0000698 fltD flight defective D http://flybase.net/reports/FBgn0000698.html gene 16-Dec-15 2015_12 "flightless,jumping defective,partially" FBgn0040967 CG18666 http://flybase.net/reports/FBgn0040967.html protein_coding_gene 0004864=protein phosphatase inhibitor activity "0043666=regulation of phosphoprotein phosphatase activity, 0009966=regulation of signal transduction" IPR007062=Protein phosphatase inhibitor 2 (IPP-2) CG18666 16-Dec-15 2015_12 viable FBgn0016822 l(1)MZ1 lethal (1) MZ1 http://flybase.net/reports/FBgn0016822.html gene M1 16-Dec-15 2015_12 "lethal,recessive" FBgn0038674 CG14285 http://flybase.net/reports/FBgn0038674.html protein_coding_gene "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG14285 16-Dec-15 2015_12 viable FBgn0001613 l(1)dd9 lethal (1) discs degenerate 9 http://flybase.net/reports/FBgn0001613.html gene "d.deg.-9, l(1)d deg-9, l(1)d.deg.-9, l(1)d.deg.9" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0003630 Su(var)323 Suppressor of variegation 323 http://flybase.net/reports/FBgn0003630.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable,non-suppressor of variegation" FBgn0022397 HelI Helicase I http://flybase.net/reports/FBgn0022397.html gene 0004003=ATP-dependent DNA helicase activity dhel I 16-Dec-15 2015_12 FBgn0030620 CG5662 http://flybase.net/reports/FBgn0030620.html protein_coding_gene 0006626=protein targeting to mitochondrion 0005741=mitochondrial outer membrane CG5662 16-Dec-15 2015_12 ENSDARG00000029415(mtx2) WBGene00022516(mtx-2) ENSXETG00000001802(mtx2) ENSMUSG00000027099(Mtx2) ENSG00000128654(MTX2) viable DRSC19957 K 0.21012613 0.021352914 0.798962988 0.345411497 1.443347485 2.077063662 FBgn0000227 Bsg25A Blastoderm-specific gene 25A http://flybase.net/reports/FBgn0000227.html protein_coding_gene "0043035=chromatin insulator sequence binding, 0043565=sequence-specific DNA binding" "0031937=positive regulation of chromatin silencing, 0001700=embryonic development via the syncytial blastoderm" "0005677=chromatin silencing complex, 0005634=nucleus" "clone 1.70, CG12205, early boundary factor, Elba, bsg25A, anon-EST:Liang-1.70, blastoderm-specific gene 25A, Elba1" IPR018379=BEN domain CG12205 16-Dec-15 2015_12 " embryonic stage | syncytial blastoderm , embryonic stage | stage 4 " organism

viable FBgn0053431 5SrRNA:CR33431 5SrRNA:CR33431 http://flybase.net/reports/FBgn0053431.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33431 CR33431 16-Dec-15 2015_12 FBgn0065035 AlkB AlkB http://flybase.net/reports/FBgn0065035.html "FBgn0043008, FBgn0053250" protein_coding_gene "0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 0055114=oxidation-reduction process "unnamed, BEST:LD02396, alkB, CG33250" "IPR027450=Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR005123=Oxoglutarate/iron-dependent dioxygenase" CG33250 16-Dec-15 2015_12 WBGene00021783(Y51H7C.5) ENSXETG00000011086(ALKBH1) ENSMUSG00000079036 ENSG00000100601(ALKBH1) viable FBgn0061164 l(1)3At lethal (1) 3At http://flybase.net/reports/FBgn0061164.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022299 l(1)M120.1 lethal (1) M120.1 http://flybase.net/reports/FBgn0022299.html gene M120.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0067354 l(3)95EFb lethal (3) 95EFb http://flybase.net/reports/FBgn0067354.html gene 16-Dec-15 2015_12 "lethal,recessive" embryo FBgn0267960 CR46240 http://flybase.net/reports/FBgn0267960.html non_protein_coding_gene lincRNA.507 CR46240 16-Dec-15 2015_12 FBgn0260115 2L4515 http://flybase.net/reports/FBgn0260115.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0016633 E(gl)3A Enhancer of glass 3A http://flybase.net/reports/FBgn0016633.html gene 16-Dec-15 2015_12 FBgn0065833 l(2)SH0343 lethal (2) SH0343 http://flybase.net/reports/FBgn0065833.html gene l(2)SH2 0343 16-Dec-15 2015_12 "lethal,recessive" FBgn0069100 mus325 mutagen-sensitive 325 http://flybase.net/reports/FBgn0069100.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0035382 Or63a Odorant receptor 63a http://flybase.net/reports/FBgn0035382.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell 0032590=dendrite membrane "CG9969, 63a, DOR28, 63B.1" "IPR004117=Olfactory receptor, Drosophila" CG9969 16-Dec-15 2015_12 viable FBgn0002609 E(spl)m3-HLH "Enhancer of split m3, helix-loop-helix" http://flybase.net/reports/FBgn0002609.html FBgn0010046 protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0048749=compound eye development, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007219=Notch signaling pathway" 0005634=nucleus "CG8346, m3, E(spl)C, E(spl)C m3, E(spl)-m3, split locus enhancer protein m3, E(spl)m3, HLHM3, HLHm3, E(spl)M3, HLH-m3, E(spl) region transcript m3, bHLHc14, E(Spl)-HLH-m3, Enhancer of split m3" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG8346 16-Dec-15 2015_12 ENSDARG00000014722(her1) " embryonic stage | stage 13 , embryonic stage | 6-14 hr , adult stage | female " " embryonic/larval midgut | restricted

, Malpighian tubule

" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutellar bristle,scutum & macrochaetah-1J3" FBgn0069964 CG41048 http://flybase.net/reports/FBgn0069964.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038179 CG9312 http://flybase.net/reports/FBgn0038179.html protein_coding_gene 0051726=regulation of cell cycle CT26517 CG9312 16-Dec-15 2015_12 "viable,fertile" FBgn0023522 CG11596 http://flybase.net/reports/FBgn0023522.html protein_coding_gene EG:39E1.1 "IPR012901=N2227-like, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG11596 16-Dec-15 2015_12 ENSDARG00000031102(zgc:112985) YNL092W() WBGene00013015(Y48E1C.2) ENSXETG00000001046(C9orf41) ENSMUSG00000024726(2410127L17Rik) ENSG00000156017(C9orf41) "partially lethal - majority die,some die during pupal stage" FBgn0053136 CG33136 http://flybase.net/reports/FBgn0053136.html FBgn0045410 protein_coding_gene NEST:bs04e10 CG33136 16-Dec-15 2015_12 DRSC05744 K 0.282007055 0.333004056 0.274885732 -0.077189528 -0.580113665 2.276284776 FBgn0027175 l(2)60Ai lethal (2) 60Ai http://flybase.net/reports/FBgn0027175.html FBgn0027174 gene "l(2)60i, Unassigned in Interval 2" 16-Dec-15 2015_12 lethal FBgn0065564 l(2)SH0981 lethal (2) SH0981 http://flybase.net/reports/FBgn0065564.html gene l(2)SH2 0981 16-Dec-15 2015_12 "lethal,recessive" FBgn0050158 CG30158 http://flybase.net/reports/FBgn0050158.html "FBgn0033116, FBgn0040675, FBgn0040676, FBgn0063683" protein_coding_gene 0005525=GTP binding 0007264=small GTPase mediated signal transduction 0016020=membrane "BcDNA:RE28276, CG15243, CG15244, CG9464" "IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020849=Small GTPase superfamily, Ras type" CG30158 16-Dec-15 2015_12 WBGene00006055(ssr-2) viable FBgn0030616 RpL37a Ribosomal protein L37a http://flybase.net/reports/FBgn0030616.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "RpL37A, RpL37, CG9091" "IPR011332=Zinc-binding ribosomal protein, IPR011331=Ribosomal protein L37ae/L37e, IPR018267=Ribosomal protein L37e, conserved site, IPR001569=Ribosomal protein L37e" CG9091 16-Dec-15 2015_12 ENSDARG00000034291(LOC100000999) "YLR185W(RPL37A),YDR500C(RPL37B)" "WBGene00012179(W01D2.1),WBGene00004451(rpl-37)" ENSXETG00000027024(RPL37) "ENSMUSG00000041841(Rpl37),ENSMUSG00000049247(Rpl37-ps1)" ENSG00000145592(RPL37) DRSC21646 IEK 2.623496224 -1.228223652 1.381275095 -3.479774948 1.152827343 3.696013203 FBgn0040079 pkaap pkaap http://flybase.net/reports/FBgn0040079.html FBgn0028524 protein_coding_gene 0051018=protein kinase A binding "0038032=termination of G-protein coupled receptor signaling pathway, 0008104=protein localization" "BG:DS02740.4, CG4132, DS02740.4" IPR016137=RGS domain CG4132 16-Dec-15 2015_12 ENSDARG00000059549(si:dkey-197m14.4) WBGene00004348(rgs-5) ENSXETG00000005787(AKAP10) ENSMUSG00000047804(Akap10) ENSG00000108599(AKAP10) "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040131 l(2)22Ah lethal (2) 22Ah http://flybase.net/reports/FBgn0040131.html gene B 16-Dec-15 2015_12 "lethal,recessive" FBgn0011554 ëáTry ëáTrypsin http://flybase.net/reports/FBgn0011554.html FBgn0014415 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "CG12386, ESTS:169C4S, DmEtaTry, anon-sts17, SP57, 169C4S, etaTry, etaTrypsin" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG12386 16-Dec-15 2015_12 viable FBgn0041161 blue bluestreak http://flybase.net/reports/FBgn0041161.html FBgn0036404 protein_coding_gene "0007317=regulation of pole plasm oskar mRNA localization, 0045451=pole plasm oskar mRNA localization, 0008104=protein localization, 0008103=oocyte microtubule cytoskeleton polarization" "CG6451, bls" "IPR006573=NEUZ domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG6451 16-Dec-15 2015_12 ENSXETG00000017842(NEURL4) ENSMUSG00000047284(Neurl4) ENSG00000215041(NEURL4) viable FBgn0004752 l(3)89Be lethal (3) 89Be http://flybase.net/reports/FBgn0004752.html gene 16-Dec-15 2015_12 lethal FBgn0265846 CR44635 http://flybase.net/reports/FBgn0265846.html non_protein_coding_gene CR44635 16-Dec-15 2015_12 FBgn0015759 MHC95F-associated-protein MHC95F-associated protein http://flybase.net/reports/FBgn0015759.html gene 16-Dec-15 2015_12 FBgn0016856 l(1)N37 lethal (1) N37 http://flybase.net/reports/FBgn0016856.html gene N37 16-Dec-15 2015_12 "lethal,recessive" FBgn0027191 l(2)60A-A lethal (2) 60A-A http://flybase.net/reports/FBgn0027191.html gene 16-Dec-15 2015_12 lethal FBgn0052551 CG32551 http://flybase.net/reports/FBgn0052551.html protein_coding_gene CG32551 16-Dec-15 2015_12 DRSC19260 E 0.371493573 0.316207893 -1.728945125 0.398283993 0.069789337 0.27659687 FBgn0004967 plph polyphase http://flybase.net/reports/FBgn0004967.html gene plp 16-Dec-15 2015_12 "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0082575 CycA::tor CycA::tor http://flybase.net/reports/FBgn0082575.html engineered_fusion_gene 16-Dec-15 2015_12 mitotic cell cycle defective S phase | ectopichs.2sev FBgn0032968 CG11634 http://flybase.net/reports/FBgn0032968.html FBgn0047350 protein_coding_gene BcDNA:AT09142 IPR009961=Protein of unknown function DUF1487 CG11634 16-Dec-15 2015_12 viable FBgn0039769 CG15534 http://flybase.net/reports/FBgn0039769.html protein_coding_gene 0004767=sphingomyelin phosphodiesterase activity "0006684=sphingomyelin metabolic process, 0006685=sphingomyelin catabolic process" aSMase "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR011160=Sphingomyelin phosphodiesterase, IPR029052=Metallo-dependent phosphatase-like, IPR008139=Saposin B type domain" CG15534 16-Dec-15 2015_12 viable FBgn0037485 CG14606 http://flybase.net/reports/FBgn0037485.html protein_coding_gene 0015149=hexose transmembrane transporter activity "0055085=transmembrane transport, 0006909=phagocytosis" 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like" CG14606 16-Dec-15 2015_12 viable FBgn0037447 Neurochondrin Neurochondrin http://flybase.net/reports/FBgn0037447.html protein_coding_gene 0003012=muscle system process "0030425=dendrite, 0043025=neuronal cell body" "dNeurochondrin, CG2330" "IPR016024=Armadillo-type fold, IPR008709=Neurochondrin, IPR011989=Armadillo-like helical" CG2330 16-Dec-15 2015_12 ENSXETG00000009669(NCDN) ENSMUSG00000028833(Ncdn) ENSG00000020129(NCDN) FBgn0027120 l(3)rI327 lethal (3) rI327 http://flybase.net/reports/FBgn0027120.html gene "unnamed, l(?)rI327, lethal (?) rI327" 16-Dec-15 2015_12 "lethal,recessive" FBgn0013253 E(var)3-7 E(var)3-7 http://flybase.net/reports/FBgn0013253.html gene E-var(3)7 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0014104 anon-4Cc anon-4Cc http://flybase.net/reports/FBgn0014104.html gene "Transcript 7, T7" 16-Dec-15 2015_12 embryonic stage | 0-3 hr FBgn0060446 l(3)S122407b lethal (3) S122407b http://flybase.net/reports/FBgn0060446.html gene 1224/07 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0266498 s-167 http://flybase.net/reports/FBgn0266498.html gene 16-Dec-15 2015_12 FBgn0267600 CR45938 http://flybase.net/reports/FBgn0267600.html non_protein_coding_gene CR45938 16-Dec-15 2015_12 FBgn0053806 His3:CG33806 His3:CG33806 http://flybase.net/reports/FBgn0053806.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33806 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33806 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0265910 CR44699 http://flybase.net/reports/FBgn0265910.html non_protein_coding_gene lincRNA.39 CR44699 16-Dec-15 2015_12 FBgn0039055 Rassf Ras association family member http://flybase.net/reports/FBgn0039055.html protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding" "0009968=negative regulation of signal transduction, 0040014=regulation of multicellular organism growth, 0010332=response to gamma radiation" "RASSF, dRASSF, dmRASSF, dRassf, Ras-associated domain family protein, Drosophila Ras association family, CG4656" "IPR029071=Ubiquitin-related domain, IPR001781=Zinc finger, LIM-type, IPR000159=Ras-associating (RA) domain, IPR011524=SARAH domain" CG4656 16-Dec-15 2015_12 "ENSDARG00000044044(rassf2l),ENSDARG00000029865(rassf2),ENSDARG00000012460(zgc:92261)" "ENSXETG00000023554(RASSF4),ENSXETG00000016851(rassf2),ENSXETG00000023392(rassf6)" "ENSMUSG00000029370(Rassf6),ENSMUSG00000027339(Rassf2),ENSMUSG00000042129(Rassf4)" "ENSG00000101265(RASSF2),ENSG00000107551(RASSF4),ENSG00000169435(RASSF6)" "viable,radiation sensitive,fertile,small body" wing FBgn0013266 E(var)A1 E(var)A1 http://flybase.net/reports/FBgn0013266.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0266511 s-477 http://flybase.net/reports/FBgn0266511.html gene 16-Dec-15 2015_12 FBgn0033816 CG4679 http://flybase.net/reports/FBgn0033816.html protein_coding_gene "0043024=ribosomal small subunit binding, 0019843=rRNA binding" 0032543=mitochondrial translation 0005739=mitochondrion RE17985p IPR002885=Pentatricopeptide repeat CG4679 16-Dec-15 2015_12 ENSDARG00000057494(ptcd3) WBGene00022464(Y110A7A.19) ENSXETG00000017970(BC090356.1) ENSMUSG00000063884(Ptcd3) ENSG00000132300(PTCD3) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0043556 Su(roDOM)3023 Su(roDOM)3023 http://flybase.net/reports/FBgn0043556.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0051658 Nnf1b Nnf1b http://flybase.net/reports/FBgn0051658.html protein_coding_gene "0007080=mitotic metaphase plate congression, 0007059=chromosome segregation" "0031617=NMS complex, 0000776=kinetochore, 0031262=Ndc80 complex" "dmNnf1R-1, Nnf1-related protein 1, CG31658" CG31658 16-Dec-15 2015_12 "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "metaphase,mesothoracic tergum" FBgn0020502 CU31.4 Cible d'Ubx 31.4 http://flybase.net/reports/FBgn0020502.html gene 31.4 16-Dec-15 2015_12 FBgn0011629 l(2)T57b4 lethal (2) T57b4 http://flybase.net/reports/FBgn0011629.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0069205 l(2)46Di lethal (2) 46Di http://flybase.net/reports/FBgn0069205.html gene Complementation group BB 16-Dec-15 2015_12 "lethal,visible,dominant" wing FBgn0261521 stich1 sticky ch1 http://flybase.net/reports/FBgn0261521.html "FBgn0016941, FBgn0011718" gene "0046983=protein dimerization activity, 0003677=DNA binding" "0007422=peripheral nervous system development, 0006355=regulation of transcription, DNA-templated" "sticky ch1-1, sticky ch, sticky ch-1, sticky-chordotonals, 1437/02" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" 16-Dec-15 2015_12 "lethal,recessive" "neuron,chordotonal organ" FBgn0033564 Pex6 Peroxin 6 http://flybase.net/reports/FBgn0033564.html "FBgn0050019, FBtr0088229, FBpp0087324, FBtr0088230, FBpp0087325, FBtr0088231, FBpp0087326" protein_coding_gene 0005524=ATP binding 0007031=peroxisome organization 0005777=peroxisome "PEX6, DmelPex6, DmCG11919, CG30019, CG11919" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG11919 16-Dec-15 2015_12 ENSDARG00000070958 YNL329C(PEX6) WBGene00004195(prx-6) ENSMUSG00000002763(Pex6) ENSG00000124587(PEX6) "viable,fertile" FBgn0037972 CG10005 http://flybase.net/reports/FBgn0037972.html FBgn0062992 protein_coding_gene BcDNA:RE59626 IPR001507=Zona pellucida domain CG10005 16-Dec-15 2015_12 viable FBgn0036886 CG9300 http://flybase.net/reports/FBgn0036886.html protein_coding_gene 0005634=nucleus IPR012584=NUC205 CG9300 16-Dec-15 2015_12 ENSDARG00000026767(zgc:109901) ENSMUSG00000018433(Nol11) ENSG00000130935(NOL11) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027864 Ogg1 8-oxoguanine DNA glycosylase http://flybase.net/reports/FBgn0027864.html protein_coding_gene "0003684=damaged DNA binding, 0003906=DNA-(apurinic or apyrimidinic site) lyase activity, 0008534=oxidized purine nucleobase lesion DNA N-glycosylase activity" "0006281=DNA repair, 0006974=cellular response to DNA damage stimulus, 0006284=base-excision repair, 0006289=nucleotide-excision repair, 0034599=cellular response to oxidative stress" 0005634=nucleus "Ogg1, BcDNA:LD19945, CG1795, dOGG1, 1795" "IPR012904=8-oxoguanine DNA glycosylase, N-terminal, IPR003265=HhH-GPD domain, IPR023170=Helix-turn-helix, base-excision DNA repair, C-terminal, IPR011257=DNA glycosylase" CG1795 16-Dec-15 2015_12 ENSDARG00000060002(ogg1) YML060W(OGG1) ENSXETG00000023668(OGG1) ENSMUSG00000030271(Ogg1) ENSG00000114026(OGG1) "viable,fertile" FBgn0031851 Aatf apoptosis antagonizing transcription factor ortholog http://flybase.net/reports/FBgn0031851.html FBgn0062181 protein_coding_gene "0043069=negative regulation of programmed cell death, 0048477=oogenesis, 0022008=neurogenesis" "0005634=nucleus, 0005730=nucleolus" "Che-1, anon-WO0118547.190, nutmeg, AATF, CG11188" "IPR012617=Apoptosis-antagonizing transcription factor, C-terminal, IPR025160=AATF leucine zipper-containing domain" CG11188 16-Dec-15 2015_12 ENSDARG00000025467(aatf) YDR299W(BFR2) WBGene00022269(Y73E7A.2) ENSXETG00000008959(AATF) ENSMUSG00000018697(Aatf) ENSG00000108270(AATF) "lethal,cell polarity defective,germline clone,viable,female sterile,partially lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,germline clone,oocyte,centrosome | germline clone,polar follicle cell,supernumerary,embryonic/larval neuroblast,ganglion mother cell" FBgn0025010 E(dpp)66C E(dpp)66C http://flybase.net/reports/FBgn0025010.html gene 16-Dec-15 2015_12 FBgn0011064 l(1)Q17 lethal (1) Q17 http://flybase.net/reports/FBgn0011064.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0065181 l(3)SH002 lethal (3) SH002 http://flybase.net/reports/FBgn0065181.html gene l(2)SH3 002 16-Dec-15 2015_12 "lethal,recessive" FBgn0019756 l(1)75B4 lethal (1) 75B4 http://flybase.net/reports/FBgn0019756.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000098 aor abdominal one reduced http://flybase.net/reports/FBgn0000098.html gene 16-Dec-15 2015_12 "visible,recessive" abdominal segment 1 FBgn0041720 snRNA:U2:34ABc small nuclear RNA U2 at 34ABc http://flybase.net/reports/FBgn0041720.html "FBgn0003919, FBgn0053788" snRNA_gene "0000398=mRNA splicing, via spliceosome" "0015030=Cajal body, 0005686=U2 snRNP" "K6, U2 snRNA, dU2, U2-34ABc, CR33788, 34B U2, small nuclear RNA U2, snRNA:U2:34ABc, snRNA:U2, U2, U2snRNA, U2:34ABc" CR33788 16-Dec-15 2015_12 FBgn0065411 l(2)SH1567 lethal (2) SH1567 http://flybase.net/reports/FBgn0065411.html gene l(2)SH2 1567 16-Dec-15 2015_12 "lethal,recessive" FBgn0015891 anon-77Fa anon-77Fa http://flybase.net/reports/FBgn0015891.html gene 13a 16-Dec-15 2015_12 FBgn0010641 l(2)07806 lethal (2) 07806 http://flybase.net/reports/FBgn0010641.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038170 CG14367 http://flybase.net/reports/FBgn0038170.html protein_coding_gene 0042384=cilium assembly "IPR023379=ADP-ribosylation factor-like 2-binding protein, domain" CG14367 16-Dec-15 2015_12 ENSDARG00000037079(ccdc104) ENSXETG00000006071(TNeu040m17.1) ENSMUSG00000020462(Ccdc104) ENSG00000163001(CCDC104) FBgn0054039 CG34039 http://flybase.net/reports/FBgn0054039.html FBgn0082901 protein_coding_gene "BP1005, unnamed" "IPR009886=HCaRG, IPR017920=COMM domain" CG34039 16-Dec-15 2015_12 ENSDARG00000061946(zgc:153556) WBGene00020901(T28F2.2) ENSXETG00000023885(BC084516.1) ENSMUSG00000032299(Commd4) "ENSG00000140365(COMMD4),ENSG00000214702(LOC732265)" FBgn0038107 CG17327 http://flybase.net/reports/FBgn0038107.html protein_coding_gene 0004045=aminoacyl-tRNA hydrolase activity "IPR002833=Peptidyl-tRNA hydrolase, PTH2, IPR023476=Peptidyl-tRNA hydrolase II domain" CG17327 16-Dec-15 2015_12 FBgn0267563 CR45903 http://flybase.net/reports/FBgn0267563.html non_protein_coding_gene CR45903 16-Dec-15 2015_12 FBgn0259481 Mob2 Mob2 http://flybase.net/reports/FBgn0259481.html "FBgn0083174, FBgn0036172, FBgn0036171, FBgn0043834, FBgn0046795" protein_coding_gene "0005515=protein binding, 0019901=protein kinase binding" "0000902=cell morphogenesis, 0007611=learning or memory, 0007616=long-term memory, 0008355=olfactory learning, 0042052=rhabdomere development, 0045886=negative regulation of synaptic growth at neuromuscular junction" "0005886=plasma membrane, 0070451=cell hair, 0016028=rhabdomere, 0071944=cell periphery, 0005737=cytoplasm" "DMob2, Dmob1, dmob2, BEST:GH06341, trezor, Dmob2, MobI, Mob1, CG11711, CG11712, BcDNA:GH13236, gh06341" IPR005301=MOB kinase activator family CG11711 16-Dec-15 2015_12 FBgn0002112 l(2)ax lethal (2) ax http://flybase.net/reports/FBgn0002112.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0002780 mod modulo http://flybase.net/reports/FBgn0002780.html FBgn0011255 protein_coding_gene "0003677=DNA binding, 0043565=sequence-specific DNA binding, 0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0008283=cell proliferation, 0007286=spermatid development" "0005634=nucleus, 0043234=protein complex, 0005737=cytoplasm, 0005730=nucleolus" "0952/14, Modulo, male sterile(3)100EF, Mod, CG2050, ms(3)100EF" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG2050 16-Dec-15 2015_12 " embryonic stage | stage 9 , embryonic stage | cellular blastoderm , embryonic stage | stage 10-12 , embryonic stage | stage 15 , embryonic stage | stage 8-10 , embryonic stage " " procephalic segment

, posterior embryonic/larval midgut

, visceral mesoderm

, mitotic domain 1,2,4,5,6,10,13,22,23

, cephalopharyngeal skeleton

, anterior embryonic/larval midgut

, head

, anal pad

, somatic mesoderm

, head mesoderm

, larval muscle system

, mesoderm

" "developmental rate defective,decreased cell size,viable,male sterile,Minute,male semi-sterile,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,polyphasic,suppressor of variegation,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,cell autonomous,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell death,increased cell size,mitotic cell cycle defective" "embryonic maxillary segment,embryonic mandibular segment,adult head,somatic clone,macrochaeta,somatic muscle,embryonic/larval posterior spiracle,embryonic labial segment,adult thorax,leg,adult abdomen,adult thorax & macrochaeta | somatic clone | cell autonomous,cell autonomous,embryonic/larval midgut" FBgn0011069 l(1)Q22 lethal (1) Q22 http://flybase.net/reports/FBgn0011069.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0039469 TwdlC TweedleC http://flybase.net/reports/FBgn0039469.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle 0040003=chitin-based cuticle development 0005578=proteinaceous extracellular matrix "TwdlB, CG14254" IPR004145=Domain of unknown function DUF243 CG14254 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0022976 shoc short circuit http://flybase.net/reports/FBgn0022976.html gene 16-Dec-15 2015_12 FBgn0040213 fs(?)BP73 fs(?)BP73 http://flybase.net/reports/FBgn0040213.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0033659 Damm Death associated molecule related to Mch2 caspase http://flybase.net/reports/FBgn0033659.html protein_coding_gene 0004197=cysteine-type endopeptidase activity "0012501=programmed cell death, 0006915=apoptotic process, 0006508=proteolysis" 0005737=cytoplasm "Daydream, damm, daydream, Death associated molecule related to Mch2, Damm/Daydream, Death Associated Molecule related to Mch2, CG18188, DAMM" "IPR011600=Peptidase C14, caspase domain, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR015917=Peptidase C14A, caspase precursor p45, core, IPR029030=Caspase-like domain, IPR002138=Peptidase C14, caspase non-catalytic subunit p10" CG18188 16-Dec-15 2015_12 "viable,fertile,visible,increased cell death" "eye,ommatidium" FBgn0259472 EP-140 http://flybase.net/reports/FBgn0259472.html gene 16-Dec-15 2015_12 visible "wing hair,wing,wing vein" FBgn0061142 l(3)S000616c lethal (3) S000616c http://flybase.net/reports/FBgn0061142.html gene 16-Jun 16-Dec-15 2015_12 lethal FBgn0260497 l(3)12563 http://flybase.net/reports/FBgn0260497.html gene 16-Dec-15 2015_12 neuroanatomy defective dendritic arborizing neuron FBgn0265158 CG44227 http://flybase.net/reports/FBgn0265158.html protein_coding_gene CG44227 16-Dec-15 2015_12 FBgn0022971 snRNP54K snRNP54K http://flybase.net/reports/FBgn0022971.html gene "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" 54K 16-Dec-15 2015_12 FBgn0024572 l(3)L7321 lethal (3) L7321 http://flybase.net/reports/FBgn0024572.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003027 ovl ovaless http://flybase.net/reports/FBgn0003027.html gene 16-Dec-15 2015_12 "male fertile,female sterile" "eye,abdomen,female,ovary" FBgn0267883 CR46171 http://flybase.net/reports/FBgn0267883.html pseudogene_attribute CG12717-related CR46171 16-Dec-15 2015_12 FBgn0262527 nsl1 non-specific lethal 1 http://flybase.net/reports/FBgn0262527.html "FBgn0038364, FBgn0085126, FBgn0262474, FBgn0010895" protein_coding_gene "0001047=core promoter binding, 0005515=protein binding, 0035035=histone acetyltransferase binding" "0007526=larval somatic muscle development, 0045893=positive regulation of transcription, DNA-templated, 0048477=oogenesis, 0007095=mitotic G2 DNA damage checkpoint, 0030718=germ-line stem cell maintenance, 0030100=regulation of endocytosis, 0030727=germarium-derived female germ-line cyst formation, 0007528=neuromuscular junction development" "0044545=NSL complex, 0005634=nucleus, 0005705=polytene chromosome interband, 0005737=cytoplasm" "waharan, NSL1, Nsl1, nonspecific lethal 1, l(3)06536, CG4699, lethal (3) 06536, l(3)S009413, E(nos), non-specific lethal 1, wah" "IPR026180=KAT8 regulatory NSL complex subunit 1, IPR029332=PEHE domain" CG4699 16-Dec-15 2015_12 ENSMUSG00000018412(1700081L11Rik) ENSG00000120071(KIAA1267) DRSC15625 EK -0.878285485 1.420826987 -0.614001692 -7.10763892 -1.862795053 -0.120618708 FBgn0023537 CG17896 http://flybase.net/reports/FBgn0023537.html protein_coding_gene "0004491=methylmalonate-semialdehyde dehydrogenase (acylating) activity, 0000062=fatty-acyl-CoA binding, 0018478=malonate-semialdehyde dehydrogenase (acetylating) activity" "0006206=pyrimidine nucleobase metabolic process, 0055114=oxidation-reduction process, 0006573=valine metabolic process, 0019859=thymine metabolic process" 0005739=mitochondrion "EG:171D11.1, 153323_at" "IPR016163=Aldehyde dehydrogenase, C-terminal, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR016161=Aldehyde/histidinol dehydrogenase, IPR015590=Aldehyde dehydrogenase domain, IPR016160=Aldehyde dehydrogenase, cysteine active site, IPR010061=Methylmalonate-semialdehyde dehydrogenase" CG17896 16-Dec-15 2015_12 ENSDARG00000053485(zgc:92082) WBGene00000114(alh-8) ENSXETG00000013304(ALDH6A1) ENSMUSG00000021238(Aldh6a1) ENSG00000119711(ALDH6A1) viable DRSC18502 E 1.240730039 0.352853847 1.96410679 0.21719568 0.643696859 0.498358802 FBgn0267289 CR45725 http://flybase.net/reports/FBgn0267289.html non_protein_coding_gene CR45725 16-Dec-15 2015_12 FBgn0264787 CR44017 http://flybase.net/reports/FBgn0264787.html non_protein_coding_gene CR44017 16-Dec-15 2015_12 FBgn0062578 Mod(var)E1047 Mod(var)E1047 http://flybase.net/reports/FBgn0062578.html gene 0006342=chromatin silencing E1047 16-Dec-15 2015_12 "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0266452 CTPsyn CTP synthase http://flybase.net/reports/FBgn0266452.html "FBgn0266440, FBgn0046344, FBgn0262707, FBgn0262154, FBgn0036478, FBgn0046343" protein_coding_gene 0003883=CTP synthase activity "0006241=CTP biosynthetic process, 0035167=larval lymph gland hemopoiesis, 0022008=neurogenesis" "0097268=cytoophidium, 0005737=cytoplasm, 0005829=cytosol" "ctp Synthase, CTP Synthase, CG6854, CTP-synthase, Cytidine synthase, CTPS, CG45070, CTP synthetase" "IPR017926=Glutamine amidotransferase, IPR004468=CTP synthase, IPR029062=Class I glutamine amidotransferase-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017456=CTP synthase, N-terminal" CG45070 16-Dec-15 2015_12 "lethal,recessive,small body,developmental rate defective,majority die during larval stage,neuroanatomy defective,viable" "cytoophidiumnos.UTR.THsimVP16,egg chamber,cytoophidiumAct.PU,follicle cell,cytoophidium | cell autonomous | somatic clonetub.PU,cell autonomous,somatic clone,cytoophidium | somatic clonetub.PU,cytoophidium | germline clone,germline clone,ganglion mother cell,embryonic/larval neuroblast" FBgn0010079 Rst(2)mth Resistance to malathion on chromosome 2 http://flybase.net/reports/FBgn0010079.html gene 16-Dec-15 2015_12 FBgn0260608 2L2938 http://flybase.net/reports/FBgn0260608.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0266814 CR45276 http://flybase.net/reports/FBgn0266814.html non_protein_coding_gene CR45276 16-Dec-15 2015_12 FBgn0261269 conv convoluted http://flybase.net/reports/FBgn0261269.html "FBgn0042652, FBgn0033920" protein_coding_gene "0008045=motor neuron axon guidance, 0007424=open tracheal system development, 0035151=regulation of tube size, open tracheal system, 0035159=regulation of tube length, open tracheal system" "ALS, CT24963, Acid labile subunit, CG8561, tartan/capricious-like, dALS, acid labile substrate, l(2)k06507b, Als, Acid Labile Subunit" "IPR001611=Leucine-rich repeat, IPR026906=Leucine rich repeat 5, IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal" CG8561 16-Dec-15 2015_12 ENSMUSG00000031639(Tlr3) FBgn0014147 dh double halteres http://flybase.net/reports/FBgn0014147.html gene 16-Dec-15 2015_12 FBgn0027146 l(3)71DEa lethal (3) 71DEa http://flybase.net/reports/FBgn0027146.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053653 Cadps Calcium-dependent secretion activator http://flybase.net/reports/FBgn0053653.html "FBgn0027577, FBgn0040042, FBgn0040483, FBtr0089272, FBtr0089273" protein_coding_gene 0005509=calcium ion binding "0045956=positive regulation of calcium ion-dependent exocytosis, 0035249=synaptic transmission, glutamatergic, 0016192=vesicle-mediated transport, 0007269=neurotransmitter secretion, 0016079=synaptic vesicle exocytosis" "0045202=synapse, 0008021=synaptic vesicle" "calcium-activated protein for secretion, CAPS, CG33653, SDCAP, dCAPS, Caps, dcaps, Calcium-activated protein for secretion, BcDNA:GH07283, Calcium activated protein for secretion, CG40477, cap, CG18026, l(4)102Fb, CG17881" "IPR014770=Munc13 homology 1, IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR010439=Calcium-dependent secretion activator" CG33653 16-Dec-15 2015_12 WBGene00006767(unc-31) "ENSMUSG00000017978(Cadps2),ENSMUSG00000054423(Cadps)" "ENSG00000081803(CADPS2),ENSG00000163618(CADPS)" "viable,touch sensitivity defective,recessive,lethal,hypoactive,neurophysiology defective,locomotor behavior defective" "neuromuscular junction,synaptic vesicle" FBgn0003591 Su(var)2-9 Suppressor of variegation 2-9 http://flybase.net/reports/FBgn0003591.html gene Su-var(2)9 16-Dec-15 2015_12 "female sterile,recessive,suppressor of variegation,dominant" FBgn0283467 Pol32 http://flybase.net/reports/FBgn0283467.html "FBgn0027559, FBgn0027887, FBgn0003213" protein_coding_gene 0070182=DNA polymerase binding "0043150=DNA synthesis involved in double-strand break repair via homologous recombination, 0006281=DNA repair" "reduced, rd, pol32, CG3975, BG:DS07295.3, BcDNA:GH08865" CG3975 16-Dec-15 2015_12 FBgn0023053 l(1)3Aj lethal (1) 3Aj http://flybase.net/reports/FBgn0023053.html gene 14-Nov 16-Dec-15 2015_12 "lethal,recessive" FBgn0051245 CG31245 http://flybase.net/reports/FBgn0051245.html "FBgn0038698, FBgn0061450" protein_coding_gene "BcDNA:AT17586, CG3575" IPR006623=Testicular haploid expressed repeat CG31245 16-Dec-15 2015_12 viable FBgn0019781 l(1)27 lethal (1) 27 http://flybase.net/reports/FBgn0019781.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033844 bbc bb in a boxcar http://flybase.net/reports/FBgn0033844.html protein_coding_gene 0004307=ethanolaminephosphotransferase activity 0008654=phospholipid biosynthetic process 0016020=membrane "dCCS2, CDP-ethanolamine Phosphotransferase, CG6016, Bbc, cept" "IPR000462=CDP-alcohol phosphatidyltransferase, IPR014472=Choline/ethanolamine phosphotransferase" CG6016 16-Dec-15 2015_12 "ENSDARG00000058716(si:dkey-208b23.1),ENSDARG00000021177(cept1),ENSDARG00000014572(chpt1)" "YNL130C(CPT1),YHR123W(EPT1)" "WBGene00009057(F22E10.5),WBGene00013024(Y49A3A.1)" "ENSXETG00000004387(cept1),ENSXETG00000002538(CHPT1)" "ENSMUSG00000040774(Cept1),ENSMUSG00000060002(Chpt1)" "ENSG00000134255(CEPT1),ENSG00000111666(CHPT1)" viable adult heart FBgn0028287 l(1)G0406 lethal (1) G0406 http://flybase.net/reports/FBgn0028287.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025339 anon-58Fd anon-58Fd http://flybase.net/reports/FBgn0025339.html gene B2.1 16-Dec-15 2015_12 FBgn0037648 CG11975 http://flybase.net/reports/FBgn0037648.html protein_coding_gene "0080025=phosphatidylinositol-3,5-bisphosphate binding, 0032266=phosphatidylinositol-3-phosphate binding" 0000045=autophagic vacuole assembly 0005737=cytoplasm PROPPIN-3 "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG11975 16-Dec-15 2015_12 ENSDARG00000021557(wdr45l) YGR223C(HSV2) WBGene00012641(Y39A1A.1) ENSXETG00000022804(wdr45l) ENSMUSG00000025173(Wdr45l) ENSG00000141580(WDR45L) "viable,fertile" FBgn0044034 Mod(rst)E188 Mod(rst)E188 http://flybase.net/reports/FBgn0044034.html gene 0001745=compound eye morphogenesis E188 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0013278 Hsp70Bb Heat-shock-protein-70Bb http://flybase.net/reports/FBgn0013278.html "FBgn0001232, FBgn0051359" protein_coding_gene "0009408=response to heat, 0001666=response to hypoxia, 0035080=heat shock-mediated polytene chromosome puffing" 0005875=microtubule associated complex "heat shock protein 70, Hsp70(87C), unnamed, Hsp70Bbc, Bb, 87C locus, Hsp 70, Dm-hsp70, hsp70Bb, Hsp70A7d, Hsp70, Protein 70, hsp70, Hsp-70, Hsp70B, dhsp70, Hsp70Bc, hsp70B, heat-shock protein 70, HSP70, hsp70 87C, DMHSP7D1, Heat shock protein 70, CG31359, hsp-70, dHsp70" "IPR013126=Heat shock protein 70 family, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR018181=Heat shock protein 70, conserved site, IPR029048=Heat shock protein 70kD, C-terminal domain" CG31359 16-Dec-15 2015_12 "aging defective,male limited,heat sensitive" FBgn0034288 CG5084 http://flybase.net/reports/FBgn0034288.html protein_coding_gene IPR007931=Protein of unknown function DUF725 CG5084 16-Dec-15 2015_12 viable FBgn0016935 smi65A smell impaired 65A http://flybase.net/reports/FBgn0016935.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0015495 l(3)65ACe lethal (3) 65ACe http://flybase.net/reports/FBgn0015495.html gene "V, Distal W5.4 Group V" 16-Dec-15 2015_12 "lethal,recessive" FBgn0020768 1731\gag 1731 element gag http://flybase.net/reports/FBgn0020768.html transposable_element_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" ORF1 "IPR025314=Domain of unknown function DUF4219, IPR001878=Zinc finger, CCHC-type" 16-Dec-15 2015_12 FBgn0041763 btd::Hsap\SP1 SP1 http://flybase.net/reports/FBgn0041763.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0015494 l(3)65ACd lethal (3) 65ACd http://flybase.net/reports/FBgn0015494.html gene "Distal W5.4 Group IV, IV" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267571 CR45911 http://flybase.net/reports/FBgn0267571.html non_protein_coding_gene pri-mir-13b-1_mir-13a_mir-2c CR45911 16-Dec-15 2015_12 FBgn0052650 CG32650 http://flybase.net/reports/FBgn0052650.html FBgn0030430 protein_coding_gene CG4410 CG32650 16-Dec-15 2015_12 viable FBgn0266216 CR44911 http://flybase.net/reports/FBgn0266216.html non_protein_coding_gene CR44911 16-Dec-15 2015_12 FBgn0016046 noah noah http://flybase.net/reports/FBgn0016046.html gene "0007417=central nervous system development, 0001708=cell fate specification" 16-Dec-15 2015_12 FBgn0028305 l(1)G0377 lethal (1) G0377 http://flybase.net/reports/FBgn0028305.html gene 16-Dec-15 2015_12 "lethal,recessive" brain FBgn0067754 l(1)G0096 lethal (1) G0096 http://flybase.net/reports/FBgn0067754.html gene 16-Dec-15 2015_12 lethal FBgn0259404 C427 http://flybase.net/reports/FBgn0259404.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing,chaeta" FBgn0069246 bum boojum http://flybase.net/reports/FBgn0069246.html gene "0048813=dendrite morphogenesis, 0007409=axonogenesis" 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,axon,dendrite,commissure" FBgn0035253 CG7971 http://flybase.net/reports/FBgn0035253.html "FBgn0025275, FBgn0064978" protein_coding_gene "0000398=mRNA splicing, via spliceosome, 0008380=RNA splicing" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "BcDNA:GH04236, anon-fast-evolving-1A7, unnamed, anon-EST:fe1A7" "IPR029360=Serine/arginine repetitive matrix protein, C-terminal" CG7971 16-Dec-15 2015_12 ENSXETG00000011374(SRRM2) ENSMUSG00000039218(Srrm2) ENSG00000167978(SRRM2) FBgn0051759 CG31759 http://flybase.net/reports/FBgn0051759.html "FBgn0047228, FBgn0063734" protein_coding_gene "ms(2)01284, 3635, BcDNA:AT13596, BcDNA:LD05405, d3635" IPR005135=Endonuclease/exonuclease/phosphatase CG31759 16-Dec-15 2015_12 ENSDARG00000030964(zgc:136374) "YMR285C(NGL2),YML118W(NGL3)" WBGene00011268(R17.2) ENSXETG00000008653(Q3ZCM2_XENTR) ENSMUSG00000043702(Pde12) ENSG00000174840(PDE12) "male sterile,recessive,partially lethal - majority die,viable" FBgn0267926 CR46207 http://flybase.net/reports/FBgn0267926.html non_protein_coding_gene lincRNA.912 CR46207 16-Dec-15 2015_12 FBgn0024668 l(2)k04207 lethal (2) k04207 http://flybase.net/reports/FBgn0024668.html gene 42/7 16-Dec-15 2015_12 "lethal,recessive" FBgn0053664 CG33664 http://flybase.net/reports/FBgn0053664.html protein_coding_gene CG33664 16-Dec-15 2015_12 FBgn0265485 BG00357 http://flybase.net/reports/FBgn0265485.html gene 16-Dec-15 2015_12 FBgn0040885 CG14189 http://flybase.net/reports/FBgn0040885.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027335 Rip11 Rab11 interacting protein http://flybase.net/reports/FBgn0027335.html "FBgn0027272, FBgn0027314, FBgn0027318, FBgn0028271, FBgn0030942, FBgn0040180" protein_coding_gene 0017137=Rab GTPase binding 0042052=rhabdomere development "l(1)G0070, dRip11, lethal (1) G0003, l(1)G0092, l(1)G0205, CG6606, l(1)G0434, l(1)G0297, l(1)G0003" "IPR000008=C2 domain, IPR019018=Rab-binding domain FIP-RBD" CG6606 16-Dec-15 2015_12 WBGene00021456(Y39F10B.1) "ENSXETG00000009541(RAB11FIP2),ENSXETG00000011781(RAB11FIP5)" "ENSMUSG00000031488(Rab11fip1),ENSMUSG00000040022(Rab11fip2)" "ENSG00000156675(RAB11FIP1),ENSG00000107560(RAB11FIP2)" "partially lethal - majority die,recessive,lethal,male,female,lethal - all die before end of P-stage,some die during pharate adult stage" "pupa,rhabdomere,somatic clone,actin cytoskeleton & eye photoreceptor cell | somatic clone,eye photoreceptor cell,rhabdomere | ectopic | somatic clone" FBgn0039529 CG5612 http://flybase.net/reports/FBgn0039529.html protein_coding_gene CG5612 16-Dec-15 2015_12 viable FBgn0021839 l(2)k15206 lethal (2) k15206 http://flybase.net/reports/FBgn0021839.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036022 CG8329 http://flybase.net/reports/FBgn0036022.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP170 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG8329 16-Dec-15 2015_12 FBgn0041838 Eth-AR205 Eth-AR205 http://flybase.net/reports/FBgn0041838.html gene Eth[AR]205 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0000061 al aristaless http://flybase.net/reports/FBgn0000061.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0048800=antennal morphogenesis, 0035015=elongation of arista core, 0022416=chaeta development, 0007449=proximal/distal pattern formation, imaginal disc, 0006355=regulation of transcription, DNA-templated, 0035218=leg disc development, 0045892=negative regulation of transcription, DNA-templated, 0007480=imaginal disc-derived leg morphogenesis, 0045747=positive regulation of Notch signaling pathway" "0005634=nucleus, 0043234=protein complex" "L13-4, CG3935, lambda13-4, AL, Aristaless, A1" "IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif, IPR009057=Homeodomain-like, IPR003654=OAR domain, IPR017970=Homeobox, conserved site" CG3935 16-Dec-15 2015_12 WBGene00044330(alr-1) ENSXETG00000021154(RAX) ENSMUSG00000024518(Rax) "ENSG00000052850(ALX4),ENSG00000180318(ALX1),ENSG00000156150(ALX3)" " larval stage | third instar , embryonic stage | stage >=10 , embryonic stage | stage >=11 , embryonic stage | stage 13 " " ventral thoracic disc | restricted

, embryonic maxillary segment | restricted

, embryonic antennal segment | restricted

, embryonic mandibular segment | restricted

, embryonic labial segment | restricted

, embryonic prothoracic segment | restricted

, embryonic metathoracic segment | restricted

, mesothoracic segment | restricted

, embryonic abdominal segment 1--8

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

" "viable,fertile,wild-type,lethal,recessive,visible,poor,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,mating defective,female,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,partially lethal - majority die" "wing,ectopic,arista,posterior scutellar bristle,scutellum,sternopleural bristle,unguis,leg,distal,mesothoracic bristle,wing vein L2,somatic clone,pleurum,tarsal segment 4,pretarsus,wing vein L1,thorax,wing vein,eye,adult thorax,macrochaeta & thorax,microchaeta & thorax,wing vein L3,tarsal segment" FBgn0263709 CR43661 http://flybase.net/reports/FBgn0263709.html non_protein_coding_gene CR43661 16-Dec-15 2015_12 FBgn0003657 swy swarthy http://flybase.net/reports/FBgn0003657.html gene 16-Dec-15 2015_12 "visible,recessive,male fertile,female fertile,fertile,viable,reduced,eye color defective,body color defective" "eye,scutellum,pigment cell" FBgn0001366 l(1)1Fe lethal (1) 1Fe http://flybase.net/reports/FBgn0001366.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027346 fs(2)58g fs(2)58g http://flybase.net/reports/FBgn0027346.html FBgn0000962 gene fs(2)[58g] 16-Dec-15 2015_12 "viable,female sterile,recessive,male fertile" egg FBgn0003688 tft tufts http://flybase.net/reports/FBgn0003688.html gene 16-Dec-15 2015_12 "viable,fertile,visible,cold sensitive" FBgn0002373 l(3)91Fe lethal (3) 91Fe http://flybase.net/reports/FBgn0002373.html FBgn0002377 gene "l(3)C4-18, l(3)92Ac, l(3)C4-9, Complementation group 5, l(3)C4-7, l(DIX43)c, C5, l(3)C4-4, l(3)BE80, l(3)BE81" 16-Dec-15 2015_12 "lethal,recessive" FBgn0061058 l(3)S022527 lethal (3) S022527 http://flybase.net/reports/FBgn0061058.html gene 0225/27 16-Dec-15 2015_12 "lethal,recessive" FBgn0086022 snoRNA:Me28S-U1130 http://flybase.net/reports/FBgn0086022.html snoRNA_gene "Me28S-Um1130, CR34651" CR34651 16-Dec-15 2015_12 FBgn0260289 GSd017 http://flybase.net/reports/FBgn0260289.html gene 16-Dec-15 2015_12 lethal FBgn0020361 anon-1D2 anon-1D2 http://flybase.net/reports/FBgn0020361.html gene 1D2 16-Dec-15 2015_12 FBgn0052354 CG32354 http://flybase.net/reports/FBgn0052354.html "FBgn0025695, FBgn0035893, FBgn0040829, FBgn0040830" protein_coding_gene 0004866=endopeptidase inhibitor activity 0005576=extracellular region "CG7027, BEST:CK01670, CG7159, CK01670, CG17355" IPR002350=Kazal domain CG32354 16-Dec-15 2015_12 ENSMUSG00000055561(Spink5) viable FBgn0002216 l(3)67BDn lethal (3) 67BDn http://flybase.net/reports/FBgn0002216.html gene 16-Dec-15 2015_12 lethal FBgn0262423 mir-281-2 mir-281-2 stem loop http://flybase.net/reports/FBgn0262423.html "FBgn0082175, FBgn0082176, FBgn0086607, FBgn0067712, FBgn0067710, FBgn0262268" miRNA_gene "CR33596, mir-281, miR-281, miR-281b, miR-281-2-star, mir-281-2, CR42975, dme-miR-281, mir-281bS, 281-2, CR33597, mir-281-2*, mir-281b, dme-mir-281-2, CR33593, miR-281-2, dme-miR-281-2-5p, miR-281bS" CR42975 16-Dec-15 2015_12 "viable,visible" wing margin FBgn0044417 Scim10 Sensitized chromosome inheritance modifier 10 http://flybase.net/reports/FBgn0044417.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0040755 CG17580 http://flybase.net/reports/FBgn0040755.html FBgn0063319 protein_coding_gene BcDNA:AT18054 CG17580 16-Dec-15 2015_12 viable FBgn0069984 BG02257 BG02257 http://flybase.net/reports/FBgn0069984.html gene 16-Dec-15 2015_12 "stress response defective,long lived,female,male,heat stress response defective,starvation stress response defective" FBgn0265842 CR44631 http://flybase.net/reports/FBgn0265842.html non_protein_coding_gene CR44631 16-Dec-15 2015_12 FBgn0063404 l(3)CG3 lethal (3) CG3 http://flybase.net/reports/FBgn0063404.html gene Complementation Group 3 16-Dec-15 2015_12 "lethal,recessive" FBgn0053179 beat-IIIb beat-IIIb http://flybase.net/reports/FBgn0053179.html "FBgn0032623, FBgn0040986" protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "beat IIIb, Beat-IIIb, CG15135, CG4855, CG33179" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR007110=Immunoglobulin-like domain" CG33179 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038536 CG7655 http://flybase.net/reports/FBgn0038536.html protein_coding_gene 0046331=lateral inhibition 0005635=nuclear envelope CG7655 16-Dec-15 2015_12 ENSDARG00000063690(si:dkey-263h23.2) ENSXETG00000024090(NRM) ENSMUSG00000059791(Nrm) "ENSG00000206484,ENSG00000206391,ENSG00000137404(NRM)" "viable,visible" chaeta FBgn0027280 l(1)G0193 lethal (1) G0193 http://flybase.net/reports/FBgn0027280.html "FBgn0029064, FBgn0029984" protein_coding_gene "CG2206, l(1)G0327" CG2206 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" FBgn0266130 144Y http://flybase.net/reports/FBgn0266130.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0067374 l(2)NC133 lethal (2) NC133 http://flybase.net/reports/FBgn0067374.html gene NC133 16-Dec-15 2015_12 "lethal,recessive" FBgn0259646 B1520 http://flybase.net/reports/FBgn0259646.html gene 16-Dec-15 2015_12 visible wing FBgn0030085 CG6999 http://flybase.net/reports/FBgn0030085.html protein_coding_gene "0000166=nucleotide binding, 0003676=nucleic acid binding" "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG6999 16-Dec-15 2015_12 ENSDARG00000043666(zgc:109995) YNR054C(ESF2) WBGene00019005(F57B10.8) ENSXETG00000005684(ABT1) ENSMUSG00000036376(Abt1) ENSG00000146109(ABT1) FBgn0003496 square square http://flybase.net/reports/FBgn0003496.html gene sq 16-Dec-15 2015_12 wing FBgn0003392 shi shibire http://flybase.net/reports/FBgn0003392.html "FBgn0030705, FBgn0045942, FBgn0045943, FBgn0045944" protein_coding_gene "0005525=GTP binding, 0003777=microtubule motor activity, 0008017=microtubule binding, 0003779=actin binding, 0003924=GTPase activity" "0046667=compound eye retinal cell programmed cell death, 0035152=regulation of tube architecture, open tracheal system, 0034334=adherens junction maintenance, 0007017=microtubule-based process, 0007435=salivary gland morphogenesis, 0030866=cortical actin cytoskeleton organization, 0001661=conditioned taste aversion, 0050803=regulation of synapse structure or activity, 0009408=response to heat, 0032956=regulation of actin cytoskeleton organization, 0007637=proboscis extension reflex, 0030536=larval feeding behavior, 0007612=learning, 0007613=memory, 0007424=open tracheal system development, 0006898=receptor-mediated endocytosis, 0048499=synaptic vesicle membrane organization, 0007349=cellularization, 0007298=border follicle cell migration, 0000281=mitotic cytokinesis, 0036465=synaptic vesicle recycling, 0035186=syncytial blastoderm mitotic cell cycle, 0048488=synaptic vesicle endocytosis, 0045747=positive regulation of Notch signaling pathway, 0032970=regulation of actin filament-based process, 0090148=membrane fission, 0007291=sperm individualization, 0072583=clathrin-mediated endocytosis, 0072659=protein localization to plasma membrane, 0016192=vesicle-mediated transport, 0040008=regulation of growth, 0046843=dorsal appendage formation, 0030198=extracellular matrix organization, 0048489=synaptic vesicle transport, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0006897=endocytosis, 0008355=olfactory learning, 0007614=short-term memory, 0016185=synaptic vesicle budding from presynaptic membrane, 0048172=regulation of short-term neuronal synaptic plasticity, 0007427=epithelial cell migration, open tracheal system, 0001738=morphogenesis of a polarized epithelium, 1903475=mitotic actomyosin contractile ring assembly" "0005737=cytoplasm, 0072686=mitotic spindle, 0045202=synapse, 0005875=microtubule associated complex, 0070864=sperm individualization complex, 0005886=plasma membrane" "dynamin, CG18102, anon-WO0153538.12, Shi, DYN, Ddyn4, Dynamin, DNM3, Dyn, l(1)VII, Ddyn3, dyn, Shibire, dDyn, l(1)shi, shibiri, shibire, shibere, anon-WO0153538.14, Ddyn, anon-WO0153538.13" "IPR022812=Dynamin superfamily, IPR020850=GTPase effector domain, GED, IPR000375=Dynamin central domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027744=Dynamin, IPR001401=Dynamin, GTPase domain, IPR001849=Pleckstrin homology domain, IPR030381=Dynamin-type guanine nucleotide-binding (G) domain, IPR003130=Dynamin GTPase effector, IPR019762=Dynamin, GTPase region, conserved site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG18102 16-Dec-15 2015_12 "ENSDARG00000069937(dnm2),ENSDARG00000009281,ENSDARG00000032238(LOC100330088)" WBGene00001130(dyn-1) ENSXETG00000009360(dnm2) "ENSMUSG00000026825(Dnm1),ENSMUSG00000033335(Dnm2),ENSMUSG00000040265(Dnm3)" "ENSG00000106976(DNM1),ENSG00000079805(DNM2),ENSG00000197959(DNM3)" " larval stage , embryonic stage | late , adult stage && oogenesis stage , adult stage , spermatogenesis && adult stage , adult stage | male , embryonic stage | early , embryonic stage " " central nervous system

, ovary

, peripheral nervous system

, sense organ

, supraesophageal ganglion

, thoracico-abdominal ganglion

, subesophageal ganglion

, spermatogonium

, ventral nerve cord

, optic lobe

, adult head

, imaginal disc

, testis

, oocyte

, nurse cell

, antenno-maxillary complex

, spermatocyte

, male accessory gland

, retina

, adult brain

" "paralytic,heat sensitive,developmental rate defective,visible,somatic clone,phototaxis defective,locomotor behavior defective,smell perception defective,neuroanatomy defective,lethal,some die during immature adult stage,recessive,locomotor rhythm defective,neoplasia,neurophysiology defective,heat stress response defective,visual behavior defective,temperature conditional,endocytosis defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,uncoordinated,dominant,chemical resistant,feeding behavior defective,courtship behavior defective,song defective,mating defective,hypoactive,learning defective,memory defective,behavior defective,taste perception defective,male,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,gravitaxis defective,optomotor response defective,circadian behavior defective,increased cell death,mating behavior defective,flight defective,chemical sensitive,touch sensitivity defective,touch perception defective,proboscis extension reflex defective,thermotaxis behavior defective,cell growth defective,increased cell size" "eye,somatic clone,eye disc,wing hair,supernumerary,heat sensitive,ensheathing neuropil associated glial cell,glial cell,synapse,embryonic ventral epidermis,embryonic epidermis,photoreceptor cell & synaptic vesicle,embryo,apical plasma membrane | heat sensitive,coated pit,synaptic vesicle | heat sensitive,synapse | heat sensitive,oocyte,endosome,retina,garland cell & endosome,mesothoracic tarsal bristle,presumptive embryonic/larval tracheal system,synaptic vesicle,somatic muscle,epidermis,microchaeta,syncytial blastoderm embryo,endosome | heat sensitive,mesothoracic metatarsus,primary pigment cell,secondary pigment cell,ectopic,wing vein L3,wing vein L4,wing vein L5,NMJ bouton,actin filament & spermatid | conditional ts,wing cell,adherens junction & wing cell | pupal stage | conditional - heat sensitive,mouthpart,rhabdomere,eye photoreceptor cell,dorsal trunk primordium,neuromuscular junction | heat sensitive,metatarsus,embryonic/larval neuromuscular junction,rhabdomere | heat sensitive,bouton,synapse | temperature conditional,embryonic/larval tracheal system,temperature conditional,embryonic/larval dorsal trunk,ommatidium,eye photoreceptor cell & ommatidium | ectopic,sensory mother cell,neuron,mesothoracic tergum & macrochaeta,wing & macrochaeta,macrochaeta,sensillum trichodeum of antennal segment 3,sensillum basiconicum of antennal segment 3,sensillum coeloconicum of antennal segment 3,trichogen cell,tormogen cell,macrochaeta & thorax | conditional ts,microchaeta & thorax | conditional ts,dorsal row,ventral row,abdominal 2 ventral longitudinal muscle & larval somatic muscle | conditional ts,larval somatic muscle & presynaptic membrane | conditional ts,larval somatic muscle & synaptic vesicle | conditional ts,presumptive embryonic salivary gland,photoreceptor cell,optic cartridge,wing,adult mushroom body,adult brain,neuromuscular junction | heat sensitiveMhc.PW,brain,glial cell & brain & pupa | conditional tsrepo,mushroom body,mushroom body vertical lobe,dorsal multidendritic neuron ddaC,adult fat body,giant fiber neuron,mushroom body dorsal paired medial cell,mesothoracic extracoxal depressor muscle 66,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,medulla,lamina,axon & eye photoreceptor cell | conditional - heat sensitiveGMR.PF,dendrite | third instar larval stageGMR.PF,LNv neuron | third instar larval stage,dorsal appendage,dendritic arborizing neuron,dendrite | larval stage | heat sensitive109(2)80,class IV dendritic arborizing neuron,tertiary pigment cell,embryonic/larval glial cell,CSD interneuron,reticular neuropil associated glial cell,gamma Kenyon cell,synapsealrm.PD,multidendritic neuron,type II bouton,proboscis,air sac primordium,dorsal multidendritic neuron ddaC | pupal stage,border follicle cell,polar follicle cell,denticle belt,embryonic/first instar larval cuticle,denticle row 1,denticle row 2,denticle row 3,cuticle,ventral nerve cord commissure,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,wing disc,wing margin,wing margin bristle,fat body,imaginal disc,embryonic/larval neuroblast,embryonic myoblast,macrophage,embryonic/larval midgut | third instar larval stage,epithelium,female germline cyst" DRSC20373 EK 0.2744575 -1.427375881 1.648111937 -0.951967983 -1.245049712 -1.576499953 FBgn0085523 Su(Ste):CR40820 http://flybase.net/reports/FBgn0085523.html FBan0040820 non_protein_coding_gene "CG40820, CR40820" CR40820 16-Dec-15 2015_12 FBgn0034834 LS2 Large Subunit 2 http://flybase.net/reports/FBgn0034834.html protein_coding_gene "0003723=RNA binding, 0005515=protein binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0000398=mRNA splicing, via spliceosome, 0060968=regulation of gene silencing, 0033119=negative regulation of RNA splicing" 0005686=U2 snRNP "cg3162, CG3162" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006529=U2 snRNP auxilliary factor, large subunit, splicing factor, IPR000504=RNA recognition motif domain" CG3162 16-Dec-15 2015_12 "viable,lethal" DRSC04340 I -0.900722331 -1.838062114 -0.713948267 -0.004026071 0.348151905 -0.58474161 FBgn0030015 CG10761 http://flybase.net/reports/FBgn0030015.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination "0005741=mitochondrial outer membrane, 0005789=endoplasmic reticulum membrane" "IPR011016=Zinc finger, RING-CH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG10761 16-Dec-15 2015_12 viable DRSC27665 K 0.045501567 0.431620401 0.162969916 0.612334621 0.171803971 1.882791523 FBgn0065162 l(3)SH040 lethal (3) SH040 http://flybase.net/reports/FBgn0065162.html gene l(2)SH3 040 16-Dec-15 2015_12 "lethal,recessive" FBgn0264877 CR44068 http://flybase.net/reports/FBgn0264877.html non_protein_coding_gene CR44068 16-Dec-15 2015_12 FBgn0041729 p400 p400 http://flybase.net/reports/FBgn0041729.html gene 0005515=protein binding 0035060=brahma complex 16-Dec-15 2015_12 FBgn0069216 gl(3R)70-22 gl(3R)70-22 http://flybase.net/reports/FBgn0069216.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect,cephalopharyngeal skeleton" FBgn0005205 l(3)DTS9 lethal (3) DTS9 http://flybase.net/reports/FBgn0005205.html gene DTS-9 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,female sterile" FBgn0040344 CG3711 http://flybase.net/reports/FBgn0040344.html FBgn0029540 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity 0005634=nucleus EG:BACR7A4.19 "IPR015915=Kelch-type beta propeller, IPR006652=Kelch repeat type 1, IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR015916=Galactose oxidase, beta-propeller" CG3711 16-Dec-15 2015_12 ENSDARG00000015905(si:dkey-98f17.2) ENSXETG00000008276(LZTR1) ENSMUSG00000022761(Lztr1) ENSG00000099949(LZTR1) viable DRSC26706 EK 0.897802722 0.651957744 1.770357193 0.076673707 0.492580824 1.514460153 FBgn0005105 gusD gustatory D http://flybase.net/reports/FBgn0005105.html gene 0030536=larval feeding behavior 16-Dec-15 2015_12 taste perception defective FBgn0060951 l(3)S036909 lethal (3) S036909 http://flybase.net/reports/FBgn0060951.html gene "369/9, 0369/09" 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0263936 BG00004 http://flybase.net/reports/FBgn0263936.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,female limited,temperature response defective,gravitaxis defective" FBgn0037203 slif slimfast http://flybase.net/reports/FBgn0037203.html protein_coding_gene 0015174=basic amino acid transmembrane transporter activity "0003333=amino acid transmembrane transport, 0050829=defense response to Gram-negative bacterium, 0040007=growth, 0006865=amino acid transport, 0045824=negative regulation of innate immune response, 0006629=lipid metabolic process" 0016020=membrane "slifA, CG11128, Slif, Slimfast" "IPR002293=Amino acid/polyamine transporter I, IPR029485=Cationic amino acid transporter, C-terminal" CG11128 16-Dec-15 2015_12 "ENSDARG00000016439(LOC559627),ENSDARG00000037097(slc7a2),ENSDARG00000071661,ENSDARG00000020645(slc7a3),ENSDARG00000061566(LOC100003376)" "YEL063C(CAN1),YFL055W(AGP3),YBR069C(TAT1),YNL270C(ALP1),YNL268W(LYP1),YDR508C(GNP1),YCL025C(AGP1),YDR046C(BAP3),YBR068C(BAP2),YKR039W(GAP1),YOL020W(TAT2),YGR191W(HIP1),YPL274W(SAM3),YPL265W(DIP5),YLL061W(MMP1),YOR348C(PUT4),YBR132C(AGP2),YDR160W(SSY1)" "ENSXETG00000005526(SLC7A3),ENSXETG00000000683(SLC7A2),ENSXETG00000015899(),ENSXETG00000005504(SLC7A1)" "ENSMUSG00000031297(Slc7a3),ENSMUSG00000031596(Slc7a2),ENSMUSG00000054753(AU018091),ENSMUSG00000041313(Slc7a1)" "ENSG00000165349(SLC7A3),ENSG00000003989(SLC7A2),ENSG00000139514(SLC7A1)" larval stage organism | ubiquitous "viable,fertile,decreased cell number,decreased cell size,lethal - all die before end of larval stage,partially,some die during larval stage,developmental rate defective,lethal,visible,increased cell number" "wing,posterior compartment,embryonic/larval fat body,larva,lipid droplet & larval oenocyteppl.PP,lipid droplet & larval fat bodyppl.PP,lipid droplet & larval oenocyteLsp2.PH,embryonic/larval neuroblast" FBgn0031580 CG15423 http://flybase.net/reports/FBgn0031580.html protein_coding_gene CG15423 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0083253 E(smoDN)E Enhancer of smoDN group E http://flybase.net/reports/FBgn0083253.html gene 0007224=smoothened signaling pathway Group E 16-Dec-15 2015_12 "lethal,recessive" FBgn0024930 Su(var)2-b204 Su(var)2-b204 http://flybase.net/reports/FBgn0024930.html gene Su-var(2)b204 16-Dec-15 2015_12 FBgn0041738 l(2)k17019a lethal (2) k17019a http://flybase.net/reports/FBgn0041738.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031239 CG17075 http://flybase.net/reports/FBgn0031239.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17075 16-Dec-15 2015_12 "ENSMUSG00000039199(Zdhhc1),ENSMUSG00000069189(Zdhhc11)" "ENSG00000159714(ZDHHC1),ENSG00000188818(ZDHHC11)" viable DRSC00483 K -0.385386609 0.561626818 -0.131428872 -0.028656741 1.940463566 2.198337619 FBgn0263875 PL26 http://flybase.net/reports/FBgn0263875.html gene 16-Dec-15 2015_12 "embryonic/larval neuroblast,embryonic/larval brain" FBgn0015424 l(1)1CDa lethal (1) 1CDa http://flybase.net/reports/FBgn0015424.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083034 snoRNA:ë¬18S-525e snoRNA:ë¬18S-525e http://flybase.net/reports/FBgn0083034.html snoRNA_gene "psi18S-525e, CR34577" CR34577 16-Dec-15 2015_12 FBgn0050495 CG30495 http://flybase.net/reports/FBgn0050495.html FBgn0033201 protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process CG17986 "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG30495 16-Dec-15 2015_12 "ENSDARG00000045277(rdh12l),ENSDARG00000018069(rdh12),ENSDARG00000068474(si:dkey-94e7.2),ENSDARG00000058966(zgc:112332),ENSDARG00000071660,ENSDARG00000008491(LOC407663),ENSDARG00000054797(zgc:153441)" YOR246C() WBGene00000985(dhs-22) ENSXETG00000008385(rdh13) ENSMUSG00000008435(Rdh13) ENSG00000160439(RDH13) viable FBgn0037098 Wnk Wnk kinase http://flybase.net/reports/FBgn0037098.html protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0030177=positive regulation of Wnt signaling pathway, 0035220=wing disc development, 0007411=axon guidance, 0006468=protein phosphorylation, 1903288=positive regulation of potassium ion import, 0090263=positive regulation of canonical Wnt signaling pathway, 0046777=protein autophosphorylation" 0005737=cytoplasm "cg7177, DWNK, dWNK, wnk, WNK kinase, with-no-lysine kinase, CG7177, WNK homolog, WNK" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR024678=Serine/threonine-protein kinase OSR1/WNK, CCT domain" CG7177 16-Dec-15 2015_12 ENSDARG00000021611 "ENSMUSG00000045962(Wnk1),ENSMUSG00000037989(Wnk2),ENSMUSG00000041245(Wnk3-ps)" "ENSG00000060237(WNK1),ENSG00000165238(WNK2),ENSG00000196632(WNK3)" "lethal,recessive,visible,somatic clone,neuroanatomy defective,viable,size defective" "wing vein,ectopic,somatic clone,microchaeta,macrochaeta,abdominal segment,wing margin,abdominal segment | pharate adult stage,embryonic/larval peripheral nervous system,trichogen cell,posterior wing margin,wing margin bristle,wing,posterior,wing vein L4" DRSC23372 IK -1.564982365 -1.893217094 -0.761355005 -0.650185289 -1.69331069 -0.940173761 FBgn0050502 fa2h fatty acid 2-hydroylase http://flybase.net/reports/FBgn0050502.html "FBgn0033173, FBgn0033175" protein_coding_gene "0005506=iron ion binding, 0052722=fatty acid in-chain hydroxylase activity, 0020037=heme binding, 0080132=fatty acid alpha-hydroxylase activity" "0055114=oxidation-reduction process, 0006633=fatty acid biosynthetic process" 0016021=integral component of membrane "FA2H, fatty acid hydroxlase, sphingolipid-specific fatty acid hydroxylase, CG1642, CG30502, CG1645" "IPR014430=Sterol desaturase Scs7, IPR006694=Fatty acid hydroxylase, IPR001199=Cytochrome b5-like heme/steroid binding domain, IPR018506=Cytochrome b5, heme-binding site" CG30502 16-Dec-15 2015_12 YMR272C(SCS7) WBGene00007707(C25A1.5) "short lived,viable,fertile" FBgn0058347 CG40347 http://flybase.net/reports/FBgn0058347.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027298 l(1)G0137 lethal (1) G0137 http://flybase.net/reports/FBgn0027298.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0042207 CG18530 http://flybase.net/reports/FBgn0042207.html FBgn0038066 protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process CG12294 "IPR006693=Partial AB-hydrolase lipase domain, IPR029058=Alpha/Beta hydrolase fold, IPR025483=Lipase, eukaryotic" CG18530 16-Dec-15 2015_12 YKL140W(TGL1) viable DRSC15341 E 0.126313809 -0.815548406 3.197282764 -0.008054922 0.060502707 -0.525900322 FBgn0267649 pre-mod(mdg4)-H http://flybase.net/reports/FBgn0267649.html protein_coding_gene CG45987 CG45987 16-Dec-15 2015_12 FBgn0266762 CR45227 http://flybase.net/reports/FBgn0266762.html pseudogene_attribute CR45227 16-Dec-15 2015_12 FBgn0050412 CG30412 http://flybase.net/reports/FBgn0050412.html "FBgn0034843, FBgn0044680" protein_coding_gene "CG9803, anon-WO0140519.195" CG30412 16-Dec-15 2015_12 viable FBgn0030898 Andorra Andorra http://flybase.net/reports/FBgn0030898.html protein_coding_gene "CG12611, andorra, and" CG12611 16-Dec-15 2015_12 FBgn0025709 CG8083 http://flybase.net/reports/FBgn0025709.html FBgn0033370 protein_coding_gene "0001882=nucleoside binding, 0005415=nucleoside:sodium symporter activity" 0006810=transport 0016020=membrane "BEST:CK00459, CK00459, DmCnt2" "IPR011657=Concentrative nucleoside transporter C-terminal domain, IPR002668=Concentrative nucleoside transporter N-terminal domain, IPR011642=Nucleoside transporter/FeoB GTPase, Gate domain, IPR018270=Concentrative nucleoside transporter, metazoan/bacterial, IPR008276=Concentrative nucleoside transporter" CG8083 16-Dec-15 2015_12 ENSDARG00000060879(si:dkey-24l11.1) "WBGene00017868(F27E11.2),WBGene00017867(F27E11.1)" "ENSXETG00000011724(SLC28A3),ENSXETG00000009806()" "ENSMUSG00000027219(Slc28a2),ENSMUSG00000079071(Gm14085),ENSMUSG00000025726(Slc28a1),ENSMUSG00000021553(Slc28a3)" "ENSG00000137860(SLC28A2),ENSG00000156222(SLC28A1),ENSG00000197506(SLC28A3)" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC07073 I 1.553097522 0.944152137 1.099184242 0.507491467 -0.255345893 -0.239562501 FBgn0065485 l(2)SH1263 lethal (2) SH1263 http://flybase.net/reports/FBgn0065485.html gene l(2)SH2 1263 16-Dec-15 2015_12 "lethal,recessive" FBgn0034312 CG10916 http://flybase.net/reports/FBgn0034312.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0008340=determination of adult lifespan, 0035556=intracellular signal transduction" "IPR001841=Zinc finger, RING-type, IPR024518=Domain of unknown function DUF3421, IPR006616=DM9 repeat, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG10916 16-Dec-15 2015_12 "viable,fertile,long lived" FBgn0083289 E(smoDN)2047 Enhancer of smoDN 2047 http://flybase.net/reports/FBgn0083289.html gene 16-Dec-15 2015_12 FBgn0017385 l(1)15Eb lethal (1) 15Eb http://flybase.net/reports/FBgn0017385.html gene 16-Dec-15 2015_12 lethal FBgn0259730 tal-1A http://flybase.net/reports/FBgn0259730.html protein_coding_gene "0002009=morphogenesis of an epithelium, 0007015=actin filament organization, 0007476=imaginal disc-derived wing morphogenesis" "Dm1, Tal1A, ORF 1A, tal, pri, CG42384, Pep1, ORF1" CG42384 16-Dec-15 2015_12 FBgn0031663 CG8891 http://flybase.net/reports/FBgn0031663.html protein_coding_gene 0047429=nucleoside-triphosphate diphosphatase activity "0009143=nucleoside triphosphate catabolic process, 0048812=neuron projection morphogenesis" "IPR029001=Inosine triphosphate pyrophosphatase-like, IPR027502=Inosine triphosphate pyrophosphatase, IPR002637=Ham1-like protein" CG8891 16-Dec-15 2015_12 ENSDARG00000057529(si:ch73-18j6.1) YJR069C(HAM1) WBGene00001823(hap-1) ENSMUSG00000074797(Itpa) ENSG00000125877(ITPA) "viable,fertile" FBgn0005412 dsl diskless http://flybase.net/reports/FBgn0005412.html "FBgn0000498, FBgn0001583, FBgn0001622, FBgn0004658" gene "l(1)dl-1, l(1)discless-1, l(1)10Cf, l(1)DF396, l(1)dsl, l(1)C154, l(1)discless" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,cell lethal,germline clone,lethal,mitotic cell cycle defective,some die during larval stage" "imaginal disc,cell cycle" FBgn0267744 CR46075 http://flybase.net/reports/FBgn0267744.html non_protein_coding_gene lincRNA.255 CR46075 16-Dec-15 2015_12 FBgn0262036 CG42847 http://flybase.net/reports/FBgn0262036.html protein_coding_gene CG42847 16-Dec-15 2015_12 FBgn0264288 Su(Mir)3-1A2-2 http://flybase.net/reports/FBgn0264288.html gene 16-Dec-15 2015_12 FBgn0044005 Su(rst)C134 Su(rst)C134 http://flybase.net/reports/FBgn0044005.html gene 0001745=compound eye morphogenesis C134 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0037860 CG6629 http://flybase.net/reports/FBgn0037860.html protein_coding_gene 0000104=succinate dehydrogenase activity "0006099=tricarboxylic acid cycle, 0006121=mitochondrial electron transport, succinate to ubiquinone, 0006105=succinate metabolic process" "0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)" "IPR014314=Succinate dehydrogenase, cytochrome b556 subunit, IPR000701=Succinate dehydrogenase/Fumarate reductase, transmembrane subunit" CG6629 16-Dec-15 2015_12 "YKL141W(SDH3),YMR118C()" WBGene00003225(mev-1) FBgn0067098 H70 H70 http://flybase.net/reports/FBgn0067098.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal,partially lethal - majority die" "chaeta,eye,pigment cell" FBgn0063375 snoRNA:Me28S-G3277a http://flybase.net/reports/FBgn0063375.html snoRNA_gene "SnR38, Me28S-G3277a, CR32893, snoRNA:MeS28-G3277a, Snr38snoRNA, snoRNA:snR38:54Ea" CR32893 16-Dec-15 2015_12 FBgn0032455 Pih1D1 Pih1D1 http://flybase.net/reports/FBgn0032455.html protein_coding_gene 0005875=microtubule associated complex CG5792 IPR012981=PIH1 family CG5792 16-Dec-15 2015_12 viable FBgn0264914 CR44105 http://flybase.net/reports/FBgn0264914.html non_protein_coding_gene CR44105 16-Dec-15 2015_12 FBgn0036638 CG13033 http://flybase.net/reports/FBgn0036638.html FBgn0063673 protein_coding_gene BcDNA:RE50345 IPR004019=YLP motif CG13033 16-Dec-15 2015_12 viable FBgn0066372 barb barbos http://flybase.net/reports/FBgn0066372.html gene "0007611=learning or memory, 0048149=behavioral response to ethanol, 0008355=olfactory learning" barbos-1 16-Dec-15 2015_12 "memory defective,chemical sensitive" FBgn0067417 His-ë¬ Histone pseudogene http://flybase.net/reports/FBgn0067417.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0045502 Gr10a Gustatory receptor 10a http://flybase.net/reports/FBgn0045502.html "FBgn0045503, FBgn0052664" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 10B1, CG32664, Gr10B1, gr10a, GR10a" IPR013604=7TM chemoreceptor CG32664 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC18897 I -1.328997445 1.766443769 1.148231666 0.717794138 -0.523279283 -0.500800606 FBgn0262681 CR43151 http://flybase.net/reports/FBgn0262681.html non_protein_coding_gene CG43151 CR43151 16-Dec-15 2015_12 FBgn0036868 ms(3)76Ba male sterile (3) 76Ba http://flybase.net/reports/FBgn0036868.html protein_coding_gene 0007283=spermatogenesis CG14087 CG14087 16-Dec-15 2015_12 "male sterile,viable" FBgn0266067 CR44820 http://flybase.net/reports/FBgn0266067.html non_protein_coding_gene CR44820 16-Dec-15 2015_12 FBgn0083124 Uhg4 Uhg4 http://flybase.net/reports/FBgn0083124.html FBgn0259928 non_protein_coding_gene "Uhg-like 4, CR42451, dUhg4" CR42451 16-Dec-15 2015_12 FBgn0027294 l(1)G0150 lethal (1) G0150 http://flybase.net/reports/FBgn0027294.html gene 16-Dec-15 2015_12 "lethal,recessive" "wing,eye" FBgn0026323 Tak1 TGF-ë_ activated kinase 1 http://flybase.net/reports/FBgn0026323.html "FBgn0031120, FBgn0042230" protein_coding_gene "0005515=protein binding, 0031625=ubiquitin protein ligase binding, 0005524=ATP binding, 0004706=JUN kinase kinase kinase activity, 0004709=MAP kinase kinase kinase activity, 0004672=protein kinase activity" "0007256=activation of JNKK activity, 0007165=signal transduction, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0016318=ommatidial rotation, 0010506=regulation of autophagy, 0071222=cellular response to lipopolysaccharide, 0007391=dorsal closure, 0048749=compound eye development, 0006915=apoptotic process, 0046330=positive regulation of JNK cascade, 0006955=immune response, 0045087=innate immune response, 0051607=defense response to virus, 0006952=defense response, 0007249=I-kappaB kinase/NF-kappaB signaling, 0006468=protein phosphorylation, 0007254=JNK cascade, 0050829=defense response to Gram-negative bacterium, 0048802=notum morphogenesis, 0006963=positive regulation of antibacterial peptide biosynthetic process" 0005737=cytoplasm "dTak1, TGFbeta-activated kinase 1, TGF-beta activated kinase 1, TAK, tak, CG18492, dTAK1, dtak1, D-TAK, TAK1, D-tak, dTak, DTak, DmTak1, transforming growth factor-beta activated kinase 1, Transforming growth factor beta-activated kinase, Tak, TGF beta-activated kinase 1, Tak 1, CG1388, TGF-beta activated-kinase 1, TAK-1, D10, tak1, DTAK1, dTAK, transforming growth factor-beta-activated kinase 1, dTAK-1, DTak1" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR017441=Protein kinase, ATP binding site" CG18492 16-Dec-15 2015_12 ENSDARG00000020469(map3k7) ENSXETG00000018737(MAP3K7) ENSMUSG00000028284(Map3k7) ENSG00000135341(MAP3K7) "visible,size defective,immune response defective,wild-type,viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,planar polarity defective,lethal" "eye,embryonic/first instar larval cuticle,anterior,pupa,eye disc,photoreceptor cell,denticle belt,denticle row 1,neuroblast | larval stage,mesothoracic tergum,microchaeta,embryonic head,mouth hooks,embryo,dorsal,interommatidial bristle,secondary pigment cell,tertiary pigment cell,eye photoreceptor cell,ommatidium,basement membraneptc-559.1" DRSC20390 I 0.406784594 -2.323382771 -0.285452844 0.024562052 0.02045284 -0.562214973 FBgn0082329 HM840 HM840 http://flybase.net/reports/FBgn0082329.html gene 16-Dec-15 2015_12 FBgn0083032 snoRNA:ë¬18S-525g snoRNA:ë¬18S-525g http://flybase.net/reports/FBgn0083032.html snoRNA_gene "CR34580, psi18S-525g" CR34580 16-Dec-15 2015_12 FBgn0030895 CG7135 http://flybase.net/reports/FBgn0030895.html protein_coding_gene "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG7135 16-Dec-15 2015_12 "WBGene00007810(C29F7.1),WBGene00007811(C29F7.2),WBGene00014192(nhr-246)" viable FBgn0043529 anon-AE003814.1 anon-AE003814.1 http://flybase.net/reports/FBgn0043529.html gene unnamed 16-Dec-15 2015_12 FBgn0022007 l(2)k09217 lethal (2) k09217 http://flybase.net/reports/FBgn0022007.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0263379 CR43431 http://flybase.net/reports/FBgn0263379.html non_protein_coding_gene CR43431 16-Dec-15 2015_12 FBgn0024538 l(3)L1820 lethal (3) L1820 http://flybase.net/reports/FBgn0024538.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085295 CG34266 http://flybase.net/reports/FBgn0085295.html protein_coding_gene IPR007970=Protein of unknown function DUF733 CG34266 16-Dec-15 2015_12 FBgn0001696 l(1)ESHS17 lethal (1) ESHS17 http://flybase.net/reports/FBgn0001696.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086899 Tlk Tousled-like kinase http://flybase.net/reports/FBgn0086899.html "FBgn0052781, FBan0032782, FBgn0085441, FBgn0053219, FBgn0052782, FBgn0066856, FBgn0066855, FBgn0028489, FBgn0026698, FBgn0086709, FBgn0062688, FBgn0029675" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0019730=antimicrobial humoral response, 0007155=cell adhesion, 0045448=mitotic cell cycle, embryonic, 0040018=positive regulation of multicellular organism growth, 0016572=histone phosphorylation, 0051726=regulation of cell cycle, 0046777=protein autophosphorylation, 0006468=protein phosphorylation, 0006325=chromatin organization, 0008360=regulation of cell shape, 0007059=chromosome segregation" "0005654=nucleoplasm, 0005634=nucleus" "tousled-like kinase, tlk, CG32782, CG32781, anon-WO03040301.114, anon-WO03040301.116, CG12462, BcDNA:GH07910, dtlk, CG2829, TLK, EP1413, Tousled like kinase, CG34412, Tlk, CG33219, EP(X)1413, l(1)G0054" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG34412 16-Dec-15 2015_12 WBGene00006579(tlk-1) "ENSMUSG00000020694(Tlk2),ENSMUSG00000041997(Tlk1)" DRSC22926 IEK 1.810233974 0.126963814 2.051290113 -3.806916791 -2.466977625 0.333336039 FBgn0085621 CG41335 http://flybase.net/reports/FBgn0085621.html FBan0041335 protein_coding_gene 16-Dec-15 2015_12 FBgn0040723 CG5011 http://flybase.net/reports/FBgn0040723.html protein_coding_gene CG5011 16-Dec-15 2015_12 viable FBgn0026088 CG14818 http://flybase.net/reports/FBgn0026088.html "FBgn0047006, FBgn0047172" protein_coding_gene "BcDNA:RE09176, EG:63B12.12, CT34631, BcDNA:RH52516" "IPR005374=Uncharacterised protein family UPF0184, eukaryota, IPR022788=Uncharacterised protein family UPF0184" CG14818 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030640 CG6294 http://flybase.net/reports/FBgn0030640.html protein_coding_gene "IPR021917=Uncharacterised protein family, zinc metallopeptidase-like" CG6294 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "mesothoracic tergum,trichogen cell" FBgn0065780 l(2)SH0444 lethal (2) SH0444 http://flybase.net/reports/FBgn0065780.html gene l(2)SH2 0444 16-Dec-15 2015_12 "lethal,recessive" FBgn0001812 l(1)nc1 lethal (1) nc1 http://flybase.net/reports/FBgn0001812.html gene l(1)1308 16-Dec-15 2015_12 lethal FBgn0032348 CG4751 http://flybase.net/reports/FBgn0032348.html protein_coding_gene Q9VKJ1 IPR000555=JAB1/MPN/MOV34 metalloenzyme domain CG4751 16-Dec-15 2015_12 viable FBgn0263328 CR43409 http://flybase.net/reports/FBgn0263328.html non_protein_coding_gene CR43409 16-Dec-15 2015_12 FBgn0015901 anon-P1609-III anon-P1609-III http://flybase.net/reports/FBgn0015901.html gene 16-Dec-15 2015_12 FBgn0082626 S(CycEJP)3.2 S(CycEJP)3.2 http://flybase.net/reports/FBgn0082626.html gene Complementation group 3.2 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020534 l(2)k09201 lethal (2) k09201 http://flybase.net/reports/FBgn0020534.html gene l(2)09201 16-Dec-15 2015_12 "lethal,recessive" FBgn0052815 CG32815 http://flybase.net/reports/FBgn0052815.html "FBgn0029544, FBgn0042153" protein_coding_gene "CG16994, CG18830" CG32815 16-Dec-15 2015_12 "viable,fertile" FBgn0031814 retm real-time http://flybase.net/reports/FBgn0031814.html protein_coding_gene 0008526=phosphatidylinositol transporter activity 0006810=transport "0016021=integral component of membrane, 0005739=mitochondrion" CG9528 "IPR011074=CRAL/TRIO, N-terminal domain, IPR009038=GOLD domain, IPR006797=PRELI/MSF1 domain, IPR001251=CRAL-TRIO lipid binding domain" CG9528 16-Dec-15 2015_12 "ENSDARG00000068293,ENSDARG00000071257" YLR380W(CSR1) WBGene00011962(T23G5.2) "ENSXETG00000009129(SEC14L5),ENSXETG00000019485(sec14l1)" ENSMUSG00000020823(Sec14l1) "ENSG00000129657(SEC14L1),ENSG00000103184(SEC14L5)" viable FBgn0062690 EP1371 EP1371 http://flybase.net/reports/FBgn0062690.html gene EP(X)1371 16-Dec-15 2015_12 FBgn0000836 fs(1)M20 female sterile (1) M20 http://flybase.net/reports/FBgn0000836.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0266230 CR44925 http://flybase.net/reports/FBgn0266230.html non_protein_coding_gene lincRNA.684 CR44925 16-Dec-15 2015_12 FBgn0065784 l(2)SH0438 lethal (2) SH0438 http://flybase.net/reports/FBgn0065784.html gene l(2)SH2 0438 16-Dec-15 2015_12 "lethal,recessive" FBgn0022706 Ca-1 Carbonic anhydrase-1 http://flybase.net/reports/FBgn0022706.html gene CA-1 16-Dec-15 2015_12 FBgn0266572 ebo ellipsoid body open http://flybase.net/reports/FBgn0266572.html "FBgn0001337, FBgn0023538, FBgn0067912, FBgn0000540" protein_coding_gene 0008536=Ran GTPase binding "0006886=intracellular protein transport, 0007614=short-term memory, 0007628=adult walking behavior, 0007629=flight behavior, 0016319=mushroom body development, 0048036=central complex development" "Exportin 6, CG3923, EBO, Exportin-6, ellipsoid body open, EG:165H7.3, Exp1, Exp6, ebo" "IPR013598=Exportin-1/Importin-beta-like, IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain" CG3923 16-Dec-15 2015_12 FBgn0034317 CG14499 http://flybase.net/reports/FBgn0034317.html protein_coding_gene 0030246=carbohydrate binding "CR14499, CG14499" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG14499 16-Dec-15 2015_12 FBgn0083315 E(smoDN)1171 Enhancer of smoDN 1171 http://flybase.net/reports/FBgn0083315.html gene 16-Dec-15 2015_12 FBgn0267783 CR46114 http://flybase.net/reports/FBgn0267783.html non_protein_coding_gene CR46114 16-Dec-15 2015_12 FBgn0027964 l(3)S145511 lethal (3) S145511 http://flybase.net/reports/FBgn0027964.html gene 1455/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0086661 snoRNA:ë¬28S-2566 snoRNA:ë¬28S-2566 http://flybase.net/reports/FBgn0086661.html "FBgn0082985, FBgn0065072, FBgn0053686" snoRNA_gene 0005730=nucleolus "Psi28S-2566(SnoR269), snoRNA:269, chr3L:18861298..18861726, psi28s-2566, CR33686, snoR269, Dm-269" CR33686 16-Dec-15 2015_12 FBgn0266974 CR45425 http://flybase.net/reports/FBgn0266974.html non_protein_coding_gene CR45425 16-Dec-15 2015_12 FBgn0036953 CG17145 http://flybase.net/reports/FBgn0036953.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG17145 16-Dec-15 2015_12 FBgn0011058 l(1)Q11 lethal (1) Q11 http://flybase.net/reports/FBgn0011058.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0066370 btx bellatrix http://flybase.net/reports/FBgn0066370.html gene 16-Dec-15 2015_12 FBgn0031446 CG15398 http://flybase.net/reports/FBgn0031446.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006352=DNA-templated transcription, initiation" "IPR000814=TATA-box binding protein, IPR012295=Beta2-adaptin/TBP, C-terminal domain" CG15398 16-Dec-15 2015_12 viable FBgn0000057 adp adipose http://flybase.net/reports/FBgn0000057.html "FBgn0034305, FBgn0061182" protein_coding_gene "0010883=regulation of lipid storage, 0005975=carbohydrate metabolic process, 0006629=lipid metabolic process, 0010891=negative regulation of sequestering of triglyceride, 0009269=response to desiccation" "anon-WO0196371.1, anon-WO0196371.3, CG5124, anon-WO0196371.27" "IPR019775=WD40 repeat, conserved site, IPR011990=Tetratricopeptide-like helical domain, IPR001680=WD40 repeat, IPR013105=Tetratricopeptide repeat 2, IPR017986=WD40-repeat-containing domain, IPR019734=Tetratricopeptide repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR013026=Tetratricopeptide repeat-containing domain" CG5124 16-Dec-15 2015_12 ENSDARG00000059760(zgc:194983) WBGene00044440(adpr-1) ENSXETG00000020662(WDTC1) ENSMUSG00000037622(Wdtc1) ENSG00000142784(WDTC1) "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,male fertile,female fertile,stress response defective,locomotor behavior defective,recessive,starvation stress response defective,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/larval fat body,fat body,adult fat body,yolk,adult corpus allatum,dorsal appendage,oocyte,female,lipid particle" FBgn0037623 CG9801 http://flybase.net/reports/FBgn0037623.html protein_coding_gene 0003824=catalytic activity IPR001932=PPM-type phosphatase domain CG9801 16-Dec-15 2015_12 WBGene00018018(F33G12.6) FBgn0261928 CG42795 http://flybase.net/reports/FBgn0261928.html "FBgn0037800, FBgn0083944, FBan0012816, FBgn0037799" protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity "CG12816, CG3996, CG34108" IPR000195=Rab-GTPase-TBC domain CG42795 16-Dec-15 2015_12 FBgn0053476 CG33476 http://flybase.net/reports/FBgn0053476.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33476 16-Dec-15 2015_12 FBgn0065822 l(2)SH0366 lethal (2) SH0366 http://flybase.net/reports/FBgn0065822.html gene l(2)SH2 0366 16-Dec-15 2015_12 "lethal,recessive" FBgn0003072 pg prong http://flybase.net/reports/FBgn0003072.html gene 16-Dec-15 2015_12 crossvein FBgn0264959 Src42A Src oncogene at 42A http://flybase.net/reports/FBgn0264959.html "FBgn0004603, FBgn0010284, FBgn0014884, FBgn0021964, FBgn0022795, FBgn0024932, FBgn0033049" protein_coding_gene "0005524=ATP binding, 0004715=non-membrane spanning protein tyrosine kinase activity, 0004713=protein tyrosine kinase activity" "0006099=tricarboxylic acid cycle, 0016477=cell migration, 0046529=imaginal disc fusion, thorax closure, 0018108=peptidyl-tyrosine phosphorylation, 0007476=imaginal disc-derived wing morphogenesis, 0042742=defense response to bacterium, 0007411=axon guidance, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0090136=epithelial cell-cell adhesion, 0007154=cell communication, 0034332=adherens junction organization, 0007391=dorsal closure, 0048749=compound eye development, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0007435=salivary gland morphogenesis, 0051017=actin filament bundle assembly, 0043277=apoptotic cell clearance, 0036335=intestinal stem cell homeostasis, 0006468=protein phosphorylation, 0007424=open tracheal system development, 0007254=JNK cascade, 0007395=dorsal closure, spreading of leading edge cells" "0005912=adherens junction, 0005886=plasma membrane, 0005737=cytoplasm" "HD-29, Su(phl)1, src42a, Src, CG14471, Dm SRC41, CG7873, Tyrosine kinase 5, Suppressor of pole hole, Dtk5, src oncogene at 42A, Suppressor of raf-like-oncogene, Dsrc41, src42A, l(2)k10108, DSrc42A, SK2-4, DmHD-29, SRC42A, Src41, src, Src42, CG44128, Dsrc42A, dSrc, Su(Raf)1, Src42a, dtk-5, SRC 42A, dtk5, Tk5, Su(D-raf)1, Su1, src42" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR001452=SH3 domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR017441=Protein kinase, ATP binding site, IPR000980=SH2 domain" CG44128 16-Dec-15 2015_12 ENSDARG00000027807(LOC567549) WBGene00005078(src-2) ENSXETG00000006166(FRK) ENSMUSG00000019779(Frk) ENSG00000111816(FRK) " embryonic stage | stage 13-16 , larval stage | third instar , embryonic stage&&pupal stage , embryonic stage | early " " visceral mesoderm

, ventral thoracic disc

, supraesophageal ganglion

, anal pad

, embryonic/larval hindgut

, eye-antennal disc

, dorsal mesothoracic disc

, ventral nerve cord

, central nervous system

,

ubiquitous " DRSC04915 IEK -0.580107243 -3.939586829 -0.874133636 -6.546117287 -3.99074456 -2.832864398 FBgn0004688 pby pebbly http://flybase.net/reports/FBgn0004688.html gene 16-Dec-15 2015_12 visible "eye,ommatidium" FBgn0034475 Obp56h Odorant-binding protein 56h http://flybase.net/reports/FBgn0034475.html protein_coding_gene 0005549=odorant binding "0042048=olfactory behavior, 0019236=response to pheromone, 0007608=sensory perception of smell, 0007606=sensory perception of chemical stimulus" 0005576=extracellular region "OBP56h, DmelObp56h, CG13874, 56h" IPR006170=Pheromone/general odorant binding protein CG13874 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0017629 Eig34C Eig34C http://flybase.net/reports/FBgn0017629.html gene "Eig34, Ecdysone-induced gene 34C" 16-Dec-15 2015_12 FBgn0032804 CG13081 http://flybase.net/reports/FBgn0032804.html protein_coding_gene CG13081 16-Dec-15 2015_12 viable FBgn0037916 CG5342 http://flybase.net/reports/FBgn0037916.html protein_coding_gene 0016740=transferase activity 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane "IPR017852=GPI ethanolamine phosphate transferase 1, C-terminal, IPR007070=GPI ethanolamine phosphate transferase 1" CG5342 16-Dec-15 2015_12 "viable,fertile" FBgn0010131 l(1)tsW2 lethal (1) tsW2 http://flybase.net/reports/FBgn0010131.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0022260 l(2)k00803 lethal (2) k00803 http://flybase.net/reports/FBgn0022260.html gene l(2)k00803 16-Dec-15 2015_12 "lethal,recessive" FBgn0033653 CG13192 http://flybase.net/reports/FBgn0033653.html protein_coding_gene "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site" CG13192 16-Dec-15 2015_12 ENSDARG00000036293(zgc:110763) ENSXETG00000006305(GNB1L) ENSMUSG00000000884(Gnb1l) ENSG00000185838(GNB1L) viable FBgn0035353 CG18334 http://flybase.net/reports/FBgn0035353.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031887 CG11289 http://flybase.net/reports/FBgn0031887.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG11289 16-Dec-15 2015_12 "WBGene00018931(ugt-52),WBGene00015369(ugt-51),WBGene00012013(ugt-54),WBGene00020182(ugt-53),WBGene00015371(C03A7.13)" "viable,visible" mesothoracic tergum FBgn0022014 l(2)k09035 lethal (2) k09035 http://flybase.net/reports/FBgn0022014.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021766 s3754 s3754 http://flybase.net/reports/FBgn0021766.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0265351 nac neuronally altered carbohydrate http://flybase.net/reports/FBgn0265351.html "FBgn0002918, FBgn0037567" protein_coding_gene "0005462=UDP-N-acetylglucosamine transmembrane transporter activity, 0005459=UDP-galactose transmembrane transporter activity, 0005456=CMP-N-acetylneuraminate transmembrane transporter activity, 0005458=GDP-mannose transmembrane transporter activity, 0005457=GDP-fucose transmembrane transporter activity, 0005460=UDP-glucose transmembrane transporter activity, 0005461=UDP-glucuronic acid transmembrane transporter activity, 0005463=UDP-N-acetylgalactosamine transmembrane transporter activity" "0036085=GDP-fucose import into Golgi lumen, 0015786=UDP-glucose transport, 0007625=grooming behavior, 0015787=UDP-glucuronic acid transport, 0015783=GDP-fucose transport, 0015789=UDP-N-acetylgalactosamine transport, 0015782=CMP-N-acetylneuraminate transport, 0015788=UDP-N-acetylglucosamine transport, 0015785=UDP-galactose transport, 0036071=N-glycan fucosylation, 0015784=GDP-mannose transport, 0036066=protein O-linked fucosylation, 0048193=Golgi vesicle transport" "0005798=Golgi-associated vesicle, 0005794=Golgi apparatus" "Golgi GDP-fucose transporter, CG9620, neuronally-altered-carbohydrate, unnamed, gfr, Nac, Gfr" IPR004853=Sugar phosphate transporter domain CG9620 16-Dec-15 2015_12 ENSDARG00000028270 WBGene00008237(C50F4.14) ENSXETG00000001017(SLC35C1) ENSMUSG00000049922(Slc35c1) ENSG00000181830(SLC35C1) FBgn0000361 Cp70 Chorion protein 70 http://flybase.net/reports/FBgn0000361.html gene 0005213=structural constituent of chorion 0007306=eggshell chorion assembly s70 16-Dec-15 2015_12 electrophoretic variant FBgn0028541 TM9SF4 Transmembrane 9 superfamily protein member 4 http://flybase.net/reports/FBgn0028541.html "FBgn0027852, FBgn0040975" protein_coding_gene 0005215=transporter activity "0061060=negative regulation of peptidoglycan recognition protein signaling pathway, 0072659=protein localization to plasma membrane, 0035010=encapsulation of foreign target, 0006909=phagocytosis, 0050829=defense response to Gram-negative bacterium" "0005886=plasma membrane, 0016021=integral component of membrane, 0005737=cytoplasm, 0005768=endosome, 0012505=endomembrane system" "CG7364, n(2)k07245, BG:DS00797.1, CG16861" IPR004240=Nonaspanin (TM9SF) CG7364 16-Dec-15 2015_12 ENSDARG00000002536(tm9sf4) "YLR083C(EMP70),YDR107C(TMN2)" WBGene00014119(ZK858.6) ENSMUSG00000068040(Tm9sf4) ENSG00000101337(TM9SF4) "viable,fertile,immune response defective,partially lethal - majority live,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "plasmatocyte,sessile hemocyte,actin cytoskeleton & plasmatocyte" FBgn0050172 CG30172 http://flybase.net/reports/FBgn0050172.html "FBgn0043545, FBgn0064786" protein_coding_gene 0005576=extracellular region "DmelCSP1, unnamed, BcDNA:RH70879, anon-AE003462.1" IPR005055=Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG30172 16-Dec-15 2015_12 viable DRSC30069 K 0.112266434 0.467004458 0.457108159 -0.03190613 0.571615307 1.678506683 FBgn0011277 HLH4C Helix loop helix protein 4C http://flybase.net/reports/FBgn0011277.html protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0051726=regulation of cell cycle" 0005634=nucleus "EG:84H4.2, DroNHLH, bHLH36, CG3052" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG3052 16-Dec-15 2015_12 "ENSXETG00000010663(),ENSXETG00000025630(twist1)" "ENSMUSG00000051251(Nhlh1),ENSMUSG00000048540(Nhlh2)" "ENSG00000104903(LYL1),ENSG00000162367(TAL1)" " embryonic stage | stage >=12 , embryonic stage " " embryonic central nervous system | restricted

, neuron

" viable DRSC18670 I -1.56652381 0.309846124 0.08543051 0.579377511 0.262325871 0.52791879 FBgn0038132 CG15887 http://flybase.net/reports/FBgn0038132.html FBgn0061394 protein_coding_gene BcDNA:RE53127 CG15887 16-Dec-15 2015_12 viable FBgn0001807 l(1)Mc52 lethal (1) Mc52 http://flybase.net/reports/FBgn0001807.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041122 l(2)45Be lethal (2) 45Be http://flybase.net/reports/FBgn0041122.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0265929 CR44718 http://flybase.net/reports/FBgn0265929.html non_protein_coding_gene CR44718 16-Dec-15 2015_12 FBgn0041157 en::ovo en::ovo http://flybase.net/reports/FBgn0041157.html engineered_fusion_gene 16-Dec-15 2015_12 "egg chamber,embryonic/first instar larval cuticle,denticle belt" FBgn0005100 fs(3)350-7 female sterile (3) 350-7 http://flybase.net/reports/FBgn0005100.html gene 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,endochorion" FBgn0266893 CR45353 http://flybase.net/reports/FBgn0266893.html non_protein_coding_gene CR45353 16-Dec-15 2015_12 FBgn0259667 B0748 http://flybase.net/reports/FBgn0259667.html gene 16-Dec-15 2015_12 visible wing vein L3 FBgn0265963 CR44750 http://flybase.net/reports/FBgn0265963.html non_protein_coding_gene CR44750 16-Dec-15 2015_12 FBgn0035138 CG13884 http://flybase.net/reports/FBgn0035138.html FBgn0047342 protein_coding_gene BcDNA:AT18596 CG13884 16-Dec-15 2015_12 "viable,fertile" FBgn0267198 CR45638 http://flybase.net/reports/FBgn0267198.html non_protein_coding_gene CR45638 16-Dec-15 2015_12 FBgn0001870 l(1)XD03 lethal (1) XD03 http://flybase.net/reports/FBgn0001870.html gene 16-Dec-15 2015_12 FBgn0005336 podM podoptera in M(3)w 124 http://flybase.net/reports/FBgn0005336.html gene "pod-M, podoptera in M(3)w-12" 16-Dec-15 2015_12 visible wing FBgn0014978 l(2)23Ab lethal (2) 23Ab http://flybase.net/reports/FBgn0014978.html gene 0007399=nervous system development 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,some die during larval stage" "peripheral nervous system,central nervous system,peripheral nervous system precursor cluster" FBgn0032266 CG18302 http://flybase.net/reports/FBgn0032266.html protein_coding_gene "0016788=hydrolase activity, acting on ester bonds" 0006629=lipid metabolic process "IPR006693=Partial AB-hydrolase lipase domain, IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold" CG18302 16-Dec-15 2015_12 ENSDARG00000018529(lipf) "YLR020C(YEH2),YLL012W(YEH1)" "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" viable FBgn0028250 l(3)91Ce lethal (3) 91Ce http://flybase.net/reports/FBgn0028250.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0065370 l(2)SH1702 lethal (2) SH1702 http://flybase.net/reports/FBgn0065370.html gene l(2)SH2 1702 16-Dec-15 2015_12 "lethal,recessive" FBgn0264361 CG43813 http://flybase.net/reports/FBgn0264361.html protein_coding_gene CG43813 16-Dec-15 2015_12 FBgn0045864 blood\ORF2 ORF2 http://flybase.net/reports/FBgn0045864.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "IPR015416=Zinc finger, H2C2-type, histone UAS binding, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0062639 EP924 EP924 http://flybase.net/reports/FBgn0062639.html gene EP(3)0924 16-Dec-15 2015_12 FBgn0263780 CG17684 http://flybase.net/reports/FBgn0263780.html "FBgn0058072, FBan0017684, FBgn0040017, FBgn0058260" protein_coding_gene "0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0016020=membrane "CG40072, CG40260" "IPR029058=Alpha/Beta hydrolase fold, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469=Dipeptidylpeptidase IV, N-terminal domain" CG17684 16-Dec-15 2015_12 WBGene00001054(dpf-1) "ENSXETG00000006574(DPP6),ENSXETG00000009512(),ENSXETG00000000625(DPP10)" FBgn0030611 CG15027 http://flybase.net/reports/FBgn0030611.html FBgn0062855 protein_coding_gene BcDNA:SD22530 IPR021346=Translation machinery-associated protein 16 CG15027 16-Dec-15 2015_12 "ENSDARG00000056053,ENSDARG00000008068(zgc:110664)" ENSXETG00000004891(C4orf43) ENSMUSG00000025591(1810029B16Rik) ENSG00000198498(C4orf43) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0047217 CR31456 http://flybase.net/reports/FBgn0047217.html FBgn0051456 non_protein_coding_gene BcDNA:LD10401 16-Dec-15 2015_12 FBgn0000395 cv-2 crossveinless 2 http://flybase.net/reports/FBgn0000395.html FBgn0034625 protein_coding_gene "0043395=heparan sulfate proteoglycan binding, 0070700=BMP receptor binding, 0036122=BMP binding" "0030510=regulation of BMP signaling pathway, 0007474=imaginal disc-derived wing vein specification, 0007476=imaginal disc-derived wing morphogenesis" 0009986=cell surface "Cv2, CT35855, Cv 2, Crossveinless 2, cv 2, CG15671, BMPER, crossveinless-2, Cv-2" "IPR001846=von Willebrand factor, type D domain, IPR001007=VWFC domain, IPR014853=Uncharacterised domain, cysteine-rich" CG15671 16-Dec-15 2015_12 ENSDARG00000040893 ENSXETG00000021129(Q3L0X3_XENTR) ENSMUSG00000031963(Bmper) ENSG00000164619(BMPER) "viable,partially lethal - majority die,cold sensitive,visible,dominant,recessive,lethal" "wing,wing vein,posterior crossvein,anterior crossvein,ectopic,posterior,crossvein" FBgn0083996 CG41354 http://flybase.net/reports/FBgn0083996.html FBan0041354 protein_coding_gene 16-Dec-15 2015_12 FBgn0014304 l(3)neo14 lethal (3) neo14 http://flybase.net/reports/FBgn0014304.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038422 CG14880 http://flybase.net/reports/FBgn0038422.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14880 16-Dec-15 2015_12 FBgn0262454 mir-1007 mir-1007 stem loop http://flybase.net/reports/FBgn0262454.html "FBgn0250803, FBgn0262318" miRNA_gene "dme-mir-1007, CR43025, miR-1007" CR43025 16-Dec-15 2015_12 viable FBgn0084002 CG41435 http://flybase.net/reports/FBgn0084002.html FBan0041435 protein_coding_gene 16-Dec-15 2015_12 FBgn0010100 Acon Aconitase http://flybase.net/reports/FBgn0010100.html "FBgn0010634, FBgn0032927, FBgn0043824" protein_coding_gene "0003994=aconitate hydratase activity, 0051539=4 iron, 4 sulfur cluster binding" 0006099=tricarboxylic acid cycle "0005739=mitochondrion, 0005811=lipid particle" "BEST:GH10550, mitochondrial aconitase, CG9244, mAc, AconM, mAcon, M-Acon, m-Aconitase, m-aconitase, mACON, hsp60, FBgn0010100, i59, aconitase, m-Acon, m-acon, acon, i204, ACONITASE, l(2)07054, ACON-1" "IPR015932=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR018136=Aconitase family, 4Fe-4S cluster binding site, IPR015931=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR000573=Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR006248=Aconitase, mitochondrial-like, IPR001030=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR015928=Aconitase/3-isopropylmalate dehydratase, swivel, IPR015937=Aconitase/isopropylmalate dehydratase" CG9244 16-Dec-15 2015_12 ENSDARG00000007294(aco2) YLR304C(ACO1) WBGene00000041(aco-2) ENSXETG00000006892(ACO2) ENSMUSG00000022477(Aco2) ENSG00000100412(ACO2) "lethal - all die during embryonic stage,recessive,lethal,viable,partially lethal,short lived,locomotor behavior defective,increased cell death" "mitochondrionple.PF,embryonic/larval brain | larval stage" FBgn0001755 l(1)M3 lethal (1) M3 http://flybase.net/reports/FBgn0001755.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0044089 E(rst)D70 E(rst)D70 http://flybase.net/reports/FBgn0044089.html gene 0001745=compound eye morphogenesis D70 16-Dec-15 2015_12 viable eye FBgn0051933 CG31933 http://flybase.net/reports/FBgn0051933.html FBgn0031366 protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "CG15622, gi22945479, gi21064045" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG31933 16-Dec-15 2015_12 viable FBgn0024705 anon-84Ac anon-84Ac http://flybase.net/reports/FBgn0024705.html gene unnamed 16-Dec-15 2015_12 FBgn0035750 CG14826 http://flybase.net/reports/FBgn0035750.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG14826 16-Dec-15 2015_12 DRSC10197 E 0.468503888 0.018254562 1.552314443 0.424096142 0.637877435 0.918861889 FBgn0015731 Fip2 Ftz-interacting protein 2 http://flybase.net/reports/FBgn0015731.html gene 0006357=regulation of transcription from RNA polymerase II promoter FIP2 16-Dec-15 2015_12 FBgn0040023 CG12575 http://flybase.net/reports/FBgn0040023.html protein_coding_gene 16-Dec-15 2015_12 FBgn0058120 CG40120 http://flybase.net/reports/FBgn0058120.html FBan0040120 protein_coding_gene 16-Dec-15 2015_12 DRSC21163 K 0.548618458 -0.037047855 -0.388348983 0.633041696 1.068674376 1.528002912 FBgn0038547 CG17803 http://flybase.net/reports/FBgn0038547.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG17803 16-Dec-15 2015_12 WBGene00004335(ref-2) viable DRSC22811 E 0.062826746 0.126168717 -0.893777183 -2.651257869 0.626585416 0.745671747 FBgn0263091 CR43359 http://flybase.net/reports/FBgn0263091.html pseudogene_attribute CR43359 16-Dec-15 2015_12 FBgn0000374 cripC crippled C http://flybase.net/reports/FBgn0000374.html gene 16-Dec-15 2015_12 "behavior defective,uncoordinated" leg FBgn0035160 hng3 hinge3 http://flybase.net/reports/FBgn0035160.html FBgn0061885 protein_coding_gene 0003677=DNA binding "CG13897, Hinge3, anon-WO0118547.557" "IPR004210=BESS motif, IPR006578=MADF domain" CG13897 16-Dec-15 2015_12 "flightless,viable" wing hinge FBgn0014102 anon-4Ca anon-4Ca http://flybase.net/reports/FBgn0014102.html gene "Transcript 3, T3" 16-Dec-15 2015_12 adult stage adult head

FBgn0265975 hbs::sns http://flybase.net/reports/FBgn0265975.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0041586 mei-217::mei-218 mei-217::mei-218 http://flybase.net/reports/FBgn0041586.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0267656 CR45994 http://flybase.net/reports/FBgn0267656.html non_protein_coding_gene CR45994 16-Dec-15 2015_12 FBgn0035529 Fdx2 Ferredoxin 2 http://flybase.net/reports/FBgn0035529.html "FBgn0047176, FBgn0062960" protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding, 0009055=electron carrier activity" "0035073=pupariation, 0045998=positive regulation of ecdysteroid biosynthetic process" 0005759=mitochondrial matrix "ferredoxin, BcDNA:RH09920, CG1319, Fdxh2, BcDNA:RE08888" "IPR001055=Adrenodoxin, IPR018298=Adrenodoxin, iron-sulphur binding site, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR012675=Beta-grasp domain" CG1319 16-Dec-15 2015_12 "ENSDARG00000056410,ENSDARG00000038956(fdx1b)" ENSXETG00000013930(FDX1) ENSMUSG00000032051(Fdx1) ENSG00000137714(FDX1) "viable,visible" trichogen cell FBgn0037552 CG7800 http://flybase.net/reports/FBgn0037552.html protein_coding_gene CT23295 "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG7800 16-Dec-15 2015_12 viable FBgn0029830 Grip Glutamate receptor binding protein http://flybase.net/reports/FBgn0029830.html FBgn0040917 protein_coding_gene "0005102=receptor binding, 0005515=protein binding" "0048644=muscle organ morphogenesis, 0000060=protein import into nucleus, translocation, 0016203=muscle attachment, 0016204=determination of muscle attachment site, 0050808=synapse organization" "0031594=neuromuscular junction, 0005798=Golgi-associated vesicle, 0043195=terminal bouton" "Glutamate receptor interacting protein, CG14447, Dgrip, GRIP, DGrip, Glutamate-receptor-interacting-protein, grip, dGRIP, dgrip, CG5980" "IPR001478=PDZ domain, IPR016313=Disks large 1" CG14447 16-Dec-15 2015_12 "ENSDARG00000027618,ENSDARG00000015053(grip1),ENSDARG00000063337(si:ch73-250d21.1)" "ENSXETG00000007324(GRIP1),ENSXETG00000011516()" "ENSMUSG00000034813(Grip1),ENSMUSG00000030098" "ENSG00000144596,ENSG00000155974(GRIP1)" "wild-type,neuroanatomy defective,viable,lethal" "ventral longitudinal muscle,adult abdomen,adult head,A1-7 ventral longitudinal muscle 1,precursor,muscle system,embryonic/larval somatic muscle,embryonic somatic muscle,lateral transverse muscle,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,bouton,presynaptic active zoneC164" FBgn0053061 CG33061 http://flybase.net/reports/FBgn0053061.html FBgn0036611 protein_coding_gene 0005261=cation channel activity 0015672=monovalent inorganic cation transport 0016020=membrane CG13057 IPR007866=TRIC channel CG33061 16-Dec-15 2015_12 FBgn0083258 E(smoDN)918 Enhancer of smoDN 918 http://flybase.net/reports/FBgn0083258.html gene 16-Dec-15 2015_12 FBgn0085558 CG41027 http://flybase.net/reports/FBgn0085558.html FBan0041027 protein_coding_gene 16-Dec-15 2015_12 FBgn0058295 CG40295 http://flybase.net/reports/FBgn0058295.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053445 5SrRNA:CR33445 5SrRNA:CR33445 http://flybase.net/reports/FBgn0053445.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33445 CR33445 16-Dec-15 2015_12 FBgn0013813 Dhc98D Dynein heavy chain at 89D http://flybase.net/reports/FBgn0013813.html protein_coding_gene "0003777=microtubule motor activity, 0042623=ATPase activity, coupled, 0003774=motor activity" 0007018=microtubule-based movement "0005858=axonemal dynein complex, 0005875=microtubule associated complex" "DHC, unnamed, CG1842, dhc, Dhc, dynein-related heavy chain polypeptide" "IPR024743=Dynein heavy chain, coiled coil stalk, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR003593=AAA+ ATPase domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013594=Dynein heavy chain, domain-1, IPR004273=Dynein heavy chain domain, IPR026983=Dynein heavy chain" CG1842 16-Dec-15 2015_12 ENSDARG00000061486(LOC569992) ENSG00000197653(DNAH10) " adult stage | female , embryonic stage , adult stage | male " testis

FBgn0019736 l(1)98B lethal (1) 98B http://flybase.net/reports/FBgn0019736.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058413 CG40413 http://flybase.net/reports/FBgn0058413.html FBan0040413 protein_coding_gene 16-Dec-15 2015_12 FBgn0031528 CG15412 http://flybase.net/reports/FBgn0031528.html protein_coding_gene CG15412 16-Dec-15 2015_12 viable FBgn0004421 gustA gustatory-defective A http://flybase.net/reports/FBgn0004421.html "FBgn0001154, FBgn0001158" gene "gust[x1], gust-A, gust[x2]" 16-Dec-15 2015_12 taste perception defective labellar taste bristle FBgn0083988 snoRNA:Me28S-C3420a snoRNA:Me28S-C3420a http://flybase.net/reports/FBgn0083988.html snoRNA_gene "Me28S-C3420a, CR34152" CR34152 16-Dec-15 2015_12 FBgn0267157 CR45597 http://flybase.net/reports/FBgn0267157.html non_protein_coding_gene CR45597 16-Dec-15 2015_12 FBgn0266766 CR45231 http://flybase.net/reports/FBgn0266766.html non_protein_coding_gene CR45231 16-Dec-15 2015_12 FBgn0263578 mir-4916 mir-4916 stem loop http://flybase.net/reports/FBgn0263578.html miRNA_gene "CR43563, dme-mir-4916" CR43563 16-Dec-15 2015_12 FBgn0036656 CG13026 http://flybase.net/reports/FBgn0036656.html protein_coding_gene CG13026 16-Dec-15 2015_12 viable FBgn0039306 RIOK2 RIO kinase 2 http://flybase.net/reports/FBgn0039306.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0009267=cellular response to starvation, 0060252=positive regulation of glial cell proliferation, 0090277=positive regulation of peptide hormone secretion, 0040018=positive regulation of multicellular organism growth, 0022008=neurogenesis" "0005737=cytoplasm, 0005634=nucleus" "CG11859, dRIOK2, Rio2" "IPR030484=Serine/threonine-protein kinase Rio2, IPR011009=Protein kinase-like domain, IPR018935=RIO kinase, conserved site, IPR015285=RIO2 kinase winged helix domain, N-terminal, IPR011991=Winged helix-turn-helix DNA-binding domain" CG11859 16-Dec-15 2015_12 ENSDARG00000035264(riok2) YNL207W(RIO2) WBGene00013688(riok-2) ENSXETG00000013194(riok2) ENSMUSG00000023846(Riok2) ENSG00000058729(RIOK2) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0028687 Rpt1 Regulatory particle triple-A ATPase 1 http://flybase.net/reports/FBgn0028687.html "FBgn0004135, FBgn0010606, FBgn0061531" protein_coding_gene "0016787=hydrolase activity, 0016887=ATPase activity, 0005524=ATP binding" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006974=cellular response to DNA damage stimulus" "0005700=polytene chromosome, 0005737=cytoplasm, 0005838=proteasome regulatory particle, 0008540=proteasome regulatory particle, base subcomplex" "l(2)43Ed, CG1341, Q7KMQ0_DROME, S7, Rpt1, AAA ATPase, 1341, p48B, l(2)05643, dRpt1, anon-WO0118547.90, Dmp48B, 19S complex subunit Rpt1, Dm_Rpt1, lethal(2)43Ed" "IPR005937=26S proteasome subunit P45, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG1341 16-Dec-15 2015_12 ENSDARG00000020101(psmc2) YKL145W(RPT1) WBGene00004501(rpt-1) ENSXETG00000023127(Psmc2) ENSMUSG00000028932(Psmc2) ENSG00000161057(PSMC2) "lethal,recessive,neuroanatomy defective,lethal - all die during pupal stage" "intersegmental nerve,anterior fascicle & synapse" DRSC07542 IEK -3.340207102 -4.040886236 -2.245228358 -1.656881804 7.184191381 -1.702103651 FBgn0001704 l(1)ESHS25 lethal (1) ESHS25 http://flybase.net/reports/FBgn0001704.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0046696 RNaseP:RNA Ribonuclease P RNA http://flybase.net/reports/FBgn0046696.html non_protein_coding_gene 0004526=ribonuclease P activity 0030677=ribonuclease P complex "chr3R:27043287..27043402, RNase P RNA, P RNA, CR32868" CR32868 16-Dec-15 2015_12 FBgn0003599 Su(var)3-8 Suppressor of variegation 3-8 http://flybase.net/reports/FBgn0003599.html gene Su-var(3)8 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant,heat sensitive,female sterile" FBgn0000795 fs(1)de6 female sterile (1) defective eggs 6 http://flybase.net/reports/FBgn0000795.html gene de6 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion,endochorion" FBgn0050374 CR30374 http://flybase.net/reports/FBgn0050374.html pseudogene_attribute CG30374 CR30374 16-Dec-15 2015_12 FBgn0036796 CG18231 http://flybase.net/reports/FBgn0036796.html protein_coding_gene "0005506=iron ion binding, 0004656=procollagen-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum "IPR011990=Tetratricopeptide-like helical domain, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG18231 16-Dec-15 2015_12 "viable,fertile" FBgn0260225 CR42499 http://flybase.net/reports/FBgn0260225.html pseudogene_attribute CG42499 CR42499 16-Dec-15 2015_12 FBgn0038007 Cyp313a3 Cyp313a3 http://flybase.net/reports/FBgn0038007.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "313a3, CG10093" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG10093 16-Dec-15 2015_12 YDR402C(DIT2) viable FBgn0043546 anon-AE002656.1 anon-AE002656.1 http://flybase.net/reports/FBgn0043546.html gene Extra1 16-Dec-15 2015_12 FBgn0013596 l(3)B12-3-31 lethal (3) B12-3-31 http://flybase.net/reports/FBgn0013596.html gene 16-Dec-15 2015_12 lethal FBgn0266021 CR44786 http://flybase.net/reports/FBgn0266021.html non_protein_coding_gene lincRNA.219 CR44786 16-Dec-15 2015_12 FBgn0067053 R19 R19 http://flybase.net/reports/FBgn0067053.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die" FBgn0060678 l(3)S077009b lethal (3) S077009b http://flybase.net/reports/FBgn0060678.html gene 0770/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0045485 Gr36c Gustatory receptor 36c http://flybase.net/reports/FBgn0045485.html "FBgn0032628, FBgn0045488, FBgn0051748" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG15137, Gr36B.3, Gr36B3, Gustatory receptor 36B3, CG31748, GR36c" IPR013604=7TM chemoreceptor CG31748 16-Dec-15 2015_12 viable FBgn0264084 CR43753 http://flybase.net/reports/FBgn0264084.html non_protein_coding_gene lincRNA.13 CR43753 16-Dec-15 2015_12 FBgn0266597 ewg::Dvir\ewg http://flybase.net/reports/FBgn0266597.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0265312 CR44285 http://flybase.net/reports/FBgn0265312.html non_protein_coding_gene CR44285 16-Dec-15 2015_12 FBgn0002389 l(3)93Df lethal (3) 93Df http://flybase.net/reports/FBgn0002389.html gene "l(3)er19, er19" 16-Dec-15 2015_12 "lethal,recessive,locomotor behavior defective" wing FBgn0037819 CG14688 http://flybase.net/reports/FBgn0037819.html protein_coding_gene 0048244=phytanoyl-CoA dioxygenase activity 0001561=fatty acid alpha-oxidation 0005777=peroxisome IPR008775=Phytanoyl-CoA dioxygenase CG14688 16-Dec-15 2015_12 ENSDARG00000029905(phyhd1) WBGene00013650(Y105C5B.9) ENSXETG00000012919(PHYHD1) ENSMUSG00000079484(Phyhd1) viable DRSC14911 I 1.715365879 1.487000648 0.35860784 0.592337658 -0.91082243 -0.422674427 FBgn0264493 rdx roadkill http://flybase.net/reports/FBgn0264493.html "FBgn0011366, FBgn0011314, FBgn0010801, FBgn0004722, FBgn0002364, FBpp0082336, FBtr0082873, FBgn0061865, FBgn0044329, FBgn0038193, FBgn0038192, FBgn0026625, FBgn0086364, FBgn0262907, FBgn0028076" protein_coding_gene "0005515=protein binding, 0042803=protein homodimerization activity" "0046330=positive regulation of JNK cascade, 0016567=protein ubiquitination, 0042067=establishment of ommatidial planar polarity, 0007349=cellularization, 0048592=eye morphogenesis, 0043065=positive regulation of apoptotic process, 0045879=negative regulation of smoothened signaling pathway, 0031648=protein destabilization, 0046331=lateral inhibition, 0042308=negative regulation of protein import into nucleus, 0030162=regulation of proteolysis" 0005634=nucleus "D-SPOP, hedgehog- induced BTB protein, Dromel_CG9924_FBtr0082871_rdx_mORF, Rdx, l(3)S086909, l(3)SG40, mei-P19, meiotic P19, Spop, lethal (3) S086909, l(3)2004, l(3)j1D1, Cul3-Hedghog-induced MATH and BTB domain-containing protein, CG9924, hedegehog-induced BTB protein, BEST:GM07940, l(3)dsl6, l(3)A6, Roadkill, SPOP, HIB, hib, l(3)dsl-6, CG10235, 0869/09, l(3)03477, CG12537, l(3)j4C7, l(3)88Aa, anon-WO0118547.577, Hh-induced MATH and BTB domain containing protein" "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR002083=MATH/TRAF domain, IPR008974=TRAF-like" CG12537 16-Dec-15 2015_12 DRSC16580 I 1.855874998 -0.122935647 0.146086333 0.250765959 -0.58438681 -0.203533946 FBgn0039988 CG12555 http://flybase.net/reports/FBgn0039988.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039896 yellow-h yellow-h http://flybase.net/reports/FBgn0039896.html protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "yell-h, h, CG1629" "IPR017996=Major royal jelly protein/Protein yellow, IPR011042=Six-bladed beta-propeller, TolB-like" CG1629 16-Dec-15 2015_12 viable FBgn0029713 CG11436 http://flybase.net/reports/FBgn0029713.html protein_coding_gene "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG11436 16-Dec-15 2015_12 FBgn0051690 CG31690 http://flybase.net/reports/FBgn0051690.html "FBgn0031447, FBgn0031448" protein_coding_gene 0016262=protein N-acetylglucosaminyltransferase activity "CG11542, CG15397" "IPR011990=Tetratricopeptide-like helical domain, IPR013618=Domain of unknown function DUF1736, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain" CG31690 16-Dec-15 2015_12 "ENSDARG00000045753(tmtc2),ENSDARG00000068527,ENSDARG00000035273(LOC555381)" WBGene00017983(F32D1.3) ENSMUSG00000036019(Tmtc2) ENSG00000179104(TMTC2) "viable,fertile" FBgn0259565 B2019 http://flybase.net/reports/FBgn0259565.html gene 16-Dec-15 2015_12 visible wing FBgn0030695 PGRP-LE Peptidoglycan recognition protein LE http://flybase.net/reports/FBgn0030695.html FBgn0045885 protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0016019=peptidoglycan receptor activity, 0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity" "0042742=defense response to bacterium, 0007165=signal transduction, 0045089=positive regulation of innate immune response, 0006952=defense response, 0009253=peptidoglycan catabolic process, 0009617=response to bacterium, 0008340=determination of adult lifespan, 0006955=immune response, 0050830=defense response to Gram-positive bacterium, 0061057=peptidoglycan recognition protein signaling pathway, 0050829=defense response to Gram-negative bacterium" "0005576=extracellular region, 0005887=integral component of plasma membrane" "anon-WO0153538.66, peptidoglycan recognition protein-LE, PGRP, pgrp-le, peptidoglycan recognition protein, CG8995" "IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria" CG8995 16-Dec-15 2015_12 "melanotic mass phenotype,heat sensitive,lethal,fertile,viable,immune response defective,short lived" "melanotic mass,heat sensitive,adult cuticle" FBgn0031107 HERC2 HECT and RLD domain containing protein 2 http://flybase.net/reports/FBgn0031107.html protein_coding_gene "0046872=metal ion binding, 0004842=ubiquitin-protein transferase activity, 0005085=guanyl-nucleotide exchange factor activity" "0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination" "0005737=cytoplasm, 0005634=nucleus" "CG11734, AF189221.1, HECT and RLD domain containing protein 2 ortholog (H. sapiens), HERC2" "IPR001199=Cytochrome b5-like heme/steroid binding domain, IPR010606=Mib-herc2, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR008979=Galactose-binding domain-like, IPR015940=Ubiquitin-associated domain, IPR004939=Anaphase-promoting complex, subunit 10/DOC domain, IPR009060=UBA-like, IPR000569=HECT domain, IPR021097=CPH domain, IPR014722=Ribosomal protein L2 domain 2, IPR000408=Regulator of chromosome condensation, RCC1" CG11734 16-Dec-15 2015_12 ENSXETG00000004148() ENSMUSG00000030451(Herc2) ENSG00000128731(HERC2) viable FBgn0010265 RpS13 Ribosomal protein S13 http://flybase.net/reports/FBgn0010265.html FBgn0021990 protein_coding_gene 0003735=structural constituent of ribosome "0000022=mitotic spindle elongation, 0006412=translation, 0007052=mitotic spindle organization" "0005737=cytoplasm, 0005840=ribosome, 0005730=nucleolus, 0000228=nuclear chromosome, 0022627=cytosolic small ribosomal subunit" "Rp17, CG13389, M(2)32, Rp S13, RPS13, M(2)29B, l(2)k09614, S13, M(2)32A, ribosomal protein S17, Minute(2)32A" "IPR009068=S15/NS1, RNA-binding, IPR023029=Ribosomal protein S15P, IPR012606=Ribosomal protein S13/S15, N-terminal, IPR000589=Ribosomal protein S15" CG13389 16-Dec-15 2015_12 ENSDARG00000036298(rps13) YDR064W(RPS13) WBGene00004482(rps-13) ENSXETG00000026454(rps13) "ENSMUSG00000069972(Rps13-ps1),ENSMUSG00000066362(Gm10159)" ENSG00000110700(RPS13) embryonic stage -- adult stage "developmental rate defective,lethal,recessive,visible,Minute,dominant,size defective,lethal - all die before end of pupal stage,some die during pupal stage" "prothoracic gland,macrochaeta,scutellar bristle,adult heart" DRSC03419 IEK 0.127403158 -1.80179533 -6.300514182 -5.071674796 3.76989015 2.252644918 FBgn0267932 CR46212 http://flybase.net/reports/FBgn0267932.html non_protein_coding_gene lincRNA.491 CR46212 16-Dec-15 2015_12 FBgn0014874 Pt5 Protein 5 http://flybase.net/reports/FBgn0014874.html gene 16-Dec-15 2015_12 FBgn0085395 Shawl Shaw-like http://flybase.net/reports/FBgn0085395.html "FBgn0032112, FBgn0032113" protein_coding_gene "0005251=delayed rectifier potassium channel activity, 0022843=voltage-gated cation channel activity, 0005249=voltage-gated potassium channel activity" "0006813=potassium ion transport, 0055085=transmembrane transport, 0051260=protein homooligomerization" 0008076=voltage-gated potassium channel complex "CG34366, CG13111, Kv3.2, CG4450, Kv3, shawl" "IPR003968=Potassium channel, voltage dependent, Kv, IPR003091=Potassium channel, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR005821=Ion transport domain, IPR003974=Potassium channel, voltage dependent, Kv3, IPR000210=BTB/POZ domain, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR028325=Voltage-gated potassium channel, IPR011333=POZ domain" CG34366 16-Dec-15 2015_12 "ENSDARG00000051852(LOC565419),ENSDARG00000032959,ENSDARG00000037933,ENSDARG00000061288(LOC799410),ENSDARG00000071134,ENSDARG00000055855" WBGene00008819(F14F11.1) "ENSXETG00000002027(),ENSXETG00000014391(KCNC1),ENSXETG00000023514()" "ENSMUSG00000058975(Kcnc1),ENSMUSG00000027895(Kcnc4),ENSMUSG00000062785(Kcnc3),ENSMUSG00000035681(Kcnc2)" "ENSG00000129159(KCNC1),ENSG00000131398(KCNC3),ENSG00000116396(KCNC4),ENSG00000166006(KCNC2)" FBgn0033429 CG12929 http://flybase.net/reports/FBgn0033429.html protein_coding_gene IPR018908=Putative transmembrane family 234 CG12929 16-Dec-15 2015_12 WBGene00044423(F53F10.8) ENSMUSG00000028797(2510006D16Rik) ENSG00000160055(TMEM234) viable FBgn0001804 l(1)Mc32 lethal (1) Mc32 http://flybase.net/reports/FBgn0001804.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267611 CR45949 http://flybase.net/reports/FBgn0267611.html non_protein_coding_gene CR45949 16-Dec-15 2015_12 FBgn0033131 CR12842 http://flybase.net/reports/FBgn0033131.html pseudogene_attribute CG12842 CR12842 16-Dec-15 2015_12 "viable,fertile" FBgn0031756 CG13992 http://flybase.net/reports/FBgn0031756.html protein_coding_gene CG13992 16-Dec-15 2015_12 viable FBgn0085196 CG34167 http://flybase.net/reports/FBgn0085196.html protein_coding_gene CG34167 16-Dec-15 2015_12 FBgn0267166 CR45606 http://flybase.net/reports/FBgn0267166.html non_protein_coding_gene CR45606 16-Dec-15 2015_12 FBgn0261984 Ire1 Inositol-requiring enzyme-1 http://flybase.net/reports/FBgn0261984.html "FBgn0038736, FBgn0041204" protein_coding_gene "0005524=ATP binding, 0004521=endoribonuclease activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0006986=response to unfolded protein, 0061541=rhabdomere morphogenesis, 0043484=regulation of RNA splicing, 0007030=Golgi organization, 0001751=compound eye photoreceptor cell differentiation, 0034976=response to endoplasmic reticulum stress, 0001752=compound eye photoreceptor fate commitment, 0006468=protein phosphorylation, 0070055=HAC1-type intron splice site recognition and cleavage, 0030968=endoplasmic reticulum unfolded protein response, 0006402=mRNA catabolic process" "0005783=endoplasmic reticulum, 0016020=membrane" "dire-1, IRE-like, ire1, Ire1, Ire-1, Inositol required 1, inositol-requiring enzyme-1, Ire, dIRE1, ire-1, CG4583, IRE1" "IPR027295=Quinonprotein alcohol dehydrogenase-like domain, IPR000719=Protein kinase domain, IPR018391=Pyrrolo-quinoline quinone beta-propeller repeat, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR010513=KEN domain, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR006567=PUG domain" CG4583 16-Dec-15 2015_12 YHR079C(IRE1) WBGene00002147(ire-1) ENSXETG00000010337(ERN2) "ENSMUSG00000020715(Ern1),ENSMUSG00000030866(Ern2)" "ENSG00000178607(ERN1),ENSG00000134398(ERN2)" FBgn0034242 CG14480 http://flybase.net/reports/FBgn0034242.html protein_coding_gene "IPR019331=FAM192A/Fyv6, N-terminal" CG14480 16-Dec-15 2015_12 ENSDARG00000041631(zgc:65774) WBGene00007705(C25A1.1) ENSMUSG00000031774(Fam192a) ENSG00000172775(FAM192A) viable FBgn0024221 ird6 immune response deficient 6 http://flybase.net/reports/FBgn0024221.html gene 0006963=positive regulation of antibacterial peptide biosynthetic process 16-Dec-15 2015_12 "lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0264704 CR43973 http://flybase.net/reports/FBgn0264704.html non_protein_coding_gene CR43973 16-Dec-15 2015_12 FBgn0003567 su(Hw) suppressor of Hairy wing http://flybase.net/reports/FBgn0003567.html FBgn0015225 protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0043035=chromatin insulator sequence binding, 0005515=protein binding, 0046872=metal ion binding" "0031936=negative regulation of chromatin silencing, 0045892=negative regulation of transcription, DNA-templated" "0005700=polytene chromosome, 0000785=chromatin, 0005634=nucleus" "SU(HW), suppressor of Hairy-wing, CG8573, Su(hw), Su(Hw), Su(HW), Su[Hw], SUHW, suppressor of hairy wing, suHw, Suppressor of Hair-Wing, su(HW), su(hw), Suppressor of Hairy-wing, suppressor of hairy-wing, Suppressor of Hairy wing" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG8573 16-Dec-15 2015_12 WBGene00012385(Y5F2A.4) " embryonic stage -- adult stage , oogenesis stage && adult stage | female " ovary

" embryonic stage -- adult stage , adult stage | female , adult stage | male " "female sterile,wild-type,male sterile,recessive,viable,lethal,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "cuticle,egg chamber,trichogen cell" FBgn0010119 l(1)2Db lethal (1) 2Db http://flybase.net/reports/FBgn0010119.html gene l(1)107 16-Dec-15 2015_12 lethal FBgn0032191 CG5734 http://flybase.net/reports/FBgn0032191.html protein_coding_gene 0035091=phosphatidylinositol binding 0043231=intracellular membrane-bounded organelle DmSNX17 IPR001683=Phox homologous domain CG5734 16-Dec-15 2015_12 ENSDARG00000021267 WBGene00008927(F17H10.3) ENSXETG00000017864(TEgg014m07.1) ENSMUSG00000029146(Snx17) ENSG00000115234(SNX17) viable FBgn0085826 CR41620 http://flybase.net/reports/FBgn0085826.html FBan0041620 rRNA_gene CR41620 16-Dec-15 2015_12 FBgn0027312 l(1)G0097 lethal (1) G0097 http://flybase.net/reports/FBgn0027312.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0045969 Tabor\gag gag http://flybase.net/reports/FBgn0045969.html transposable_element_gene "Pilgrim\gag, ORF1" 16-Dec-15 2015_12 FBgn0033160 Dhx15 DHX15 ortholog http://flybase.net/reports/FBgn0033160.html FBgn0026004 protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0008026=ATP-dependent helicase activity, 0005524=ATP binding, 0003724=RNA helicase activity, 0003676=nucleic acid binding" "0022008=neurogenesis, 1900745=positive regulation of p38MAPK cascade, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0005681=spliceosomal complex" "cg11107, clone 1.18, CG11107, anon-EST:Liang-1.18, DHX15" "IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR011709=Domain of unknown function DUF1605, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR007502=Helicase-associated domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG11107 16-Dec-15 2015_12 YGL120C(PRP43) WBGene00018967(F56D2.6) ENSXETG00000002123(DHX15) ENSMUSG00000029169(Dhx15) ENSG00000109606(DHX15) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0024710 anon-63Eb anon-63Eb http://flybase.net/reports/FBgn0024710.html gene Gene 21 16-Dec-15 2015_12 FBgn0062628 Mod(var)1038 Mod(var)1038 http://flybase.net/reports/FBgn0062628.html gene 0006342=chromatin silencing 1038 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0005746 l(1)TK238 lethal (1) TK238 http://flybase.net/reports/FBgn0005746.html gene l238 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0061175 btl::htl btl::htl http://flybase.net/reports/FBgn0061175.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0265700 CR44507 http://flybase.net/reports/FBgn0265700.html non_protein_coding_gene lincRNA.966 CR44507 16-Dec-15 2015_12 FBgn0065984 iab-4-6.s iab-4-6.s http://flybase.net/reports/FBgn0065984.html gene 4-6 s 16-Dec-15 2015_12 FBgn0259545 GG01156 http://flybase.net/reports/FBgn0259545.html gene 16-Dec-15 2015_12 visible mediproboscis FBgn0053920 CG33920 http://flybase.net/reports/FBgn0053920.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33920 16-Dec-15 2015_12 FBgn0265500 CR44369 http://flybase.net/reports/FBgn0265500.html non_protein_coding_gene CR44369 16-Dec-15 2015_12 FBgn0015353 anon-99Cb anon-99Cb http://flybase.net/reports/FBgn0015353.html gene 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0038578 MED17 Mediator complex subunit 17 http://flybase.net/reports/FBgn0038578.html FBgn0011035 protein_coding_gene "0003713=transcription coactivator activity, 0001104=RNA polymerase II transcription cofactor activity, 0033613=activating transcription factor binding" "0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint, 0009987=cellular process, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0045498=sex comb development" "0005634=nucleus, 0016592=mediator complex, 0031618=nuclear pericentric heterochromatin" "dTRAP80, Med17, dTRAP80/SRB4, p70, Trap80, dTrap80, l(3)s2956, TRAP80, CG7957, Mediator" "IPR019313=Mediator complex, subunit Med17" CG7957 16-Dec-15 2015_12 ENSDARG00000006345 WBGene00007017(mdt-17) ENSXETG00000017118(MED17) ENSMUSG00000031935(Med17) ENSG00000042429(MED17) "lethal,recessive,cell lethalcell lethal,somatic clone" embryonic/larval brain DRSC16889 IEK 0.763828301 2.94083354 -3.380947175 -0.475176501 3.150046955 2.289141517 FBgn0067641 trou trou http://flybase.net/reports/FBgn0067641.html gene "0045450=bicoid mRNA localization, 0045451=pole plasm oskar mRNA localization" 16-Dec-15 2015_12 "partially lethal - majority die,female sterile" "egg chamber,germline clone,egg" FBgn0023421 tRNA-guanylyltransferase tRNA guanylyltransferase http://flybase.net/reports/FBgn0023421.html gene 0008193=tRNA guanylyltransferase activity 16-Dec-15 2015_12 FBgn0027554 CG8042 http://flybase.net/reports/FBgn0027554.html "FBgn0044624, FBgn0046406" protein_coding_gene 0012505=endomembrane system "anon-WO0172774.24, BcDNA:GH10229, UBX domain 2 like, anon-WO0140519.245" "IPR029071=Ubiquitin-related domain, IPR001012=UBX domain, IPR012336=Thioredoxin-like fold" CG8042 16-Dec-15 2015_12 WBGene00022703(ubxn-4) ENSXETG00000024994(UBXN4) ENSMUSG00000026353(Ubxn4) ENSG00000144224(UBXN4) viable FBgn0026185 rdgG retinal degeneration G http://flybase.net/reports/FBgn0026185.html gene 16-Dec-15 2015_12 visual behavior defective "photoreceptor cell,retina" FBgn0028927 CG31834 http://flybase.net/reports/FBgn0028927.html protein_coding_gene "BG:DS00929.16, DS00929.16" 16-Dec-15 2015_12 FBgn0058181 CG40181 http://flybase.net/reports/FBgn0058181.html FBan0040181 protein_coding_gene 16-Dec-15 2015_12 FBgn0015261 Moorea Moorea http://flybase.net/reports/FBgn0015261.html region 16-Dec-15 2015_12 FBgn0011436 l(3)j12B4 lethal (3) j12B4 http://flybase.net/reports/FBgn0011436.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044519 fs(1)124 female sterile (1) 124 http://flybase.net/reports/FBgn0044519.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "germarium,egg chamber" FBgn0005556 l(3)89Ee lethal (3) 89Ee http://flybase.net/reports/FBgn0005556.html "FBgn0002368, FBgn0002439" gene "lrB, lrb, lbr, lethal-right-of-Bithorax, unnamed, l(3)rB, lethal bithorax right" 16-Dec-15 2015_12 lethal FBgn0015582 dare defective in the avoidance of repellents http://flybase.net/reports/FBgn0015582.html protein_coding_gene "0004324=ferredoxin-NADP+ reductase activity, 0015039=NADPH-adrenodoxin reductase activity, 0009055=electron carrier activity" "0042810=pheromone metabolic process, 0042331=phototaxis, 0006707=cholesterol catabolic process, 0035073=pupariation, 0055114=oxidation-reduction process, 0007591=molting cycle, chitin-based cuticle, 0042048=olfactory behavior, 0007619=courtship behavior, 0006694=steroid biosynthetic process, 0007552=metamorphosis" "0005759=mitochondrial matrix, 0005739=mitochondrion" "CG12390, W8, Dare, Adrenodoxin reductase, ADXRDTASE, AR" "IPR016040=NAD(P)-binding domain, IPR021163=Ferredoxin-NADP+ reductase, adrenodoxin-type, IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain" CG12390 16-Dec-15 2015_12 ENSDARG00000068411 YDR376W(ARH1) WBGene00013376(Y62E10A.6) ENSXETG00000027429(FDXR) ENSMUSG00000018861(Fdxr) ENSG00000161513(FDXR) " adult stage , larval stage | third instar , adult stage && oogenesis stage | stage >=S6 " " ring gland

, nurse cell

, ovary

, prothoracic gland

" "viable,smell perception defective,recessive,courtship behavior defective,male,behavior defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,dominant,maternal effect" "antennal lobe,optic lobe,ellipsoid body,fan-shaped body,thoracico-abdominal ganglion,egg,germline clone,egg chamber,mouth hooks,embryonic/larval anterior spiracle" FBgn0038721 subdued subdued http://flybase.net/reports/FBgn0038721.html protein_coding_gene "0097603=temperature-gated ion channel activity, 0005229=intracellular calcium activated chloride channel activity, 0005247=voltage-gated chloride channel activity" "0050965=detection of temperature stimulus involved in sensory perception of pain, 0050829=defense response to Gram-negative bacterium" CG16718 IPR007632=Anoctamin CG16718 16-Dec-15 2015_12 YBR086C(IST2) WBGene00010138(F56A8.1) ENSXETG00000008496(ANO2) "ENSMUSG00000031075(Ano1),ENSMUSG00000038115(Ano2)" "ENSG00000131620(ANO1),ENSG00000047617(ANO2)" "immune response defective,viable,fertile" FBgn0051143 tRNA:CR31143 transfer RNA:CR31143 http://flybase.net/reports/FBgn0051143.html FBgn0060164 tRNA_gene 0033404=UUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:L:CAA:AE002708, chr3R.trna43-LeuCAA, CR31143, AE002708.trna37-LeuCAA" CR31143 16-Dec-15 2015_12 FBgn0030178 CG2974 http://flybase.net/reports/FBgn0030178.html protein_coding_gene IPR004443=YjeF N-terminal domain CG2974 16-Dec-15 2015_12 ENSDARG00000058806(apoa1bp) YNL200C() WBGene00012476(Y18D10A.3) ENSXETG00000020391(APOA1BP) ENSMUSG00000028070(Apoa1bp) ENSG00000163382(APOA1BP) "viable,fertile,visible" trichogen cell FBgn0040962 CG15868 http://flybase.net/reports/FBgn0040962.html protein_coding_gene 16-Dec-15 2015_12 FBgn0058239 CG40239 http://flybase.net/reports/FBgn0058239.html FBan0040239 protein_coding_gene 16-Dec-15 2015_12 FBgn0266224 CR44919 http://flybase.net/reports/FBgn0266224.html non_protein_coding_gene CR44919 16-Dec-15 2015_12 FBgn0263704 T:SS-hh Signal sequence of hh http://flybase.net/reports/FBgn0263704.html engineered_tag T:hh 16-Dec-15 2015_12 FBgn0086358 Tab2 TAK1-associated binding protein 2 http://flybase.net/reports/FBgn0086358.html "FBgn0034431, FBgn0043901" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" "0009617=response to bacterium, 0045433=male courtship behavior, veined wing generated song production, 0002230=positive regulation of defense response to virus by host, 0006355=regulation of transcription, DNA-templated, 0061057=peptidoglycan recognition protein signaling pathway, 0046331=lateral inhibition, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0033160=positive regulation of protein import into nucleus, translocation, 0048813=dendrite morphogenesis" 0005634=nucleus "CG7417, dTab2, Tab2, ORF1, dTAB2, TAK1-associated Binding Protein2, cg7417, galere, TGF-beta-activated kinase 1/MAP3K7 binding protein 2, tab2, TAB2, tab-2, TAB, 7417" "IPR003892=Ubiquitin system component Cue, IPR001876=Zinc finger, RanBP2-type" CG7417 16-Dec-15 2015_12 "ENSDARG00000021509(tab2),ENSDARG00000062063(tab3)" "ENSXETG00000010567(MAP3K7IP3),ENSXETG00000021389(MAP3K7IP2)" "ENSMUSG00000015755(Tab2),ENSMUSG00000035476(Tab3)" "ENSG00000055208(TAB2),ENSG00000157625(TAB3)" FBgn0017417 axe axed http://flybase.net/reports/FBgn0017417.html gene 0007409=axonogenesis 16-Dec-15 2015_12 chordotonal organ & axon | lateral FBgn0069160 mcl(3)Z2086 mcl(3)Z2086 http://flybase.net/reports/FBgn0069160.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0002465 l(3)SG19 lethal (3) SG19 http://flybase.net/reports/FBgn0002465.html gene 16-Dec-15 2015_12 "lethal,recessive" eye-antennal disc FBgn0032908 CG9270 http://flybase.net/reports/FBgn0032908.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding, 0008559=xenobiotic-transporting ATPase activity" "0055085=transmembrane transport, 0046331=lateral inhibition" 0043190=ATP-binding cassette (ABC) transporter complex Dme_CG9270 "IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9270 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) "viable,visible" chaeta FBgn0065670 l(2)SH0686 lethal (2) SH0686 http://flybase.net/reports/FBgn0065670.html gene l(2)SH2 0686 16-Dec-15 2015_12 "lethal,recessive" FBgn0011868 tRNA:G3:55E transfer RNA:gly3:55E http://flybase.net/reports/FBgn0011868.html "FBgn0050228, FBgn0060218" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna68-GlyGCC, tRNA[Gly-GCC], tRNA:G:GCC:AE002787-a, tRNA:gly3:55E, CR30228, AE002787.trna10-GlyGCC" CR30228 16-Dec-15 2015_12 FBgn0035197 CG9130 http://flybase.net/reports/FBgn0035197.html "FBgn0044576, FBgn0044735, FBgn0046290, FBgn0046291, FBgn0052332, FBtr0072654, FBpp0072548, FBpp0072549, FBtr0072656, FBpp0072550, FBpp0072551, FBtr0072658, FBpp0072552" protein_coding_gene "CG32332, BEST:GH19464, anon-WO0140519.53, anon-WO0140519.145, BEST:GH19274" CG9130 16-Dec-15 2015_12 FBgn0051340 CG31340 http://flybase.net/reports/FBgn0051340.html protein_coding_gene 16-Dec-15 2015_12 FBgn0069128 mei(3)M19 mei(3)M19 http://flybase.net/reports/FBgn0069128.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive" FBgn0003890 ë_Tub97EF ë_-Tubulin at 97EF http://flybase.net/reports/FBgn0003890.html FBgn0039567 protein_coding_gene "0005525=GTP binding, 0005200=structural constituent of cytoskeleton, 0003924=GTPase activity" "0051298=centrosome duplication, 0051258=protein polymerization" 0005874=microtubule "beta-Tub97EF, beta97F, beta-tub, B4t, tubulin, betaTub4, betaTub98C, beta4 tubulin, Dmbeta4, beta tubulin, beta4t, beta-tubulin, Beta4-tubulin, betaTub98BC, beta-Tubulin at 97EF, betaTub97EF, beta-Tub, Beta tubulin, beta-Tubulin, betatubulin, beta4, 4t, BETA 98B, CG4869, DTB1, Tub, beta-Tubulin 97EF, T" "IPR013838=Beta tubulin, autoregulation binding site, IPR003008=Tubulin/FtsZ, GTPase domain, IPR023123=Tubulin, C-terminal, IPR002453=Beta tubulin, IPR000217=Tubulin, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR008280=Tubulin/FtsZ, C-terminal, IPR017975=Tubulin, conserved site" CG4869 16-Dec-15 2015_12 " larval stage | second instar , embryonic stage | 0-21 hr , larval stage | third instar , pupal stage , prepupal stage , larval stage | first instar " "viable,fertile" DRSC15666 E 0.995962574 -0.674885018 3.76162945 -0.319934608 0.311230994 -0.491730244 FBgn0052758 CG32758 http://flybase.net/reports/FBgn0052758.html "FBgn0029794, FBgn0029796, FBgn0040916" protein_coding_gene 0032266=phosphatidylinositol-3-phosphate binding "0006886=intracellular protein transport, 0016197=endosomal transport, 0007165=signal transduction" 0005769=early endosome "DmSNX27, CG11465, CG3130, CG3138" "IPR000159=Ras-associating (RA) domain, IPR001683=Phox homologous domain, IPR001478=PDZ domain, IPR028667=Sorting nexin-27, IPR029071=Ubiquitin-related domain" CG32758 16-Dec-15 2015_12 "ENSDARG00000016977(snx27),ENSDARG00000033804(si:dkeyp-39e9.2)" WBGene00009116(F25H2.2) ENSMUSG00000028136(Snx27) ENSG00000143376(SNX27) "viable,visible" trichogen cell FBgn0003907 tyl tinylike http://flybase.net/reports/FBgn0003907.html gene "ty-l, l(1)10Cb" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,visible,viable,poor,lethal" macrochaeta FBgn0067351 l(3)95Ea lethal (3) 95Ea http://flybase.net/reports/FBgn0067351.html gene 16-Dec-15 2015_12 "lethal,recessive" "eye,somatic clone,mesothoracic tergum & macrochaeta | somatic clone,wing vein,wing margin" FBgn0028886 CG15279 http://flybase.net/reports/FBgn0028886.html FBgn0045951 protein_coding_gene "0005416=cation:amino acid symporter activity, 0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity" "0044745=amino acid transmembrane import, 0006836=neurotransmitter transport" 0016021=integral component of membrane "anon-WO0149848.9, DmNAT6, DS03431.1, BG:DS03431.1" IPR000175=Sodium:neurotransmitter symporter CG15279 16-Dec-15 2015_12 viable FBgn0003705 ti tarsi irregular http://flybase.net/reports/FBgn0003705.html gene 16-Dec-15 2015_12 partially lethal - majority live "eye,tarsal segment 3,tarsal segment 4" FBgn0035152 CG3386 http://flybase.net/reports/FBgn0035152.html protein_coding_gene IPR006578=MADF domain CG3386 16-Dec-15 2015_12 "viable,fertile" FBgn0267031 CR45475 http://flybase.net/reports/FBgn0267031.html non_protein_coding_gene CR45475 16-Dec-15 2015_12 FBgn0060356 l(3)S140901 lethal (3) S140901 http://flybase.net/reports/FBgn0060356.html gene 1409/01 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0035852 CG7387 http://flybase.net/reports/FBgn0035852.html FBgn0044555 protein_coding_gene "0051082=unfolded protein binding, 0031072=heat shock protein binding" 0006457=protein folding anon-WO0140519.72 "IPR001305=Heat shock protein DnaJ, cysteine-rich domain, IPR008971=HSP40/DnaJ peptide-binding, IPR002939=Chaperone DnaJ, C-terminal, IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site" CG7387 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0035541 CG15019 http://flybase.net/reports/FBgn0035541.html protein_coding_gene IPR018784=Learning associated protein 18-like CG15019 16-Dec-15 2015_12 ENSDARG00000055360(zgc:123180) ENSMUSG00000020224(Llph) viable FBgn0030008 CG2129 http://flybase.net/reports/FBgn0030008.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG2129 16-Dec-15 2015_12 FBgn0058092 CG40092 http://flybase.net/reports/FBgn0058092.html FBan0040092 protein_coding_gene 16-Dec-15 2015_12 FBgn0015876 anon-48Ae anon-48Ae http://flybase.net/reports/FBgn0015876.html gene "VII, transcript group VII" 16-Dec-15 2015_12 FBgn0262435 mir-1009 mir-1009 stem loop http://flybase.net/reports/FBgn0262435.html "FBgn0250805, FBgn0262287" miRNA_gene "CR42994, dme-mir-1009, miR-1009" CR42994 16-Dec-15 2015_12 viable FBgn0083269 E(smoDN)390 Enhancer of smoDN 390 http://flybase.net/reports/FBgn0083269.html gene 16-Dec-15 2015_12 FBgn0016041 Tom40 Translocase of outer membrane 40 http://flybase.net/reports/FBgn0016041.html "FBgn0027267, FBgn0029960" protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0071456=cellular response to hypoxia, 0006626=protein targeting to mitochondrion, 0055085=transmembrane transport" "0005742=mitochondrial outer membrane translocase complex, 0005739=mitochondrion" "tom40, membrane import protein, CG12157, l(1)G0216, ms15, dtom40, ms(1)15, mit" "IPR023614=Porin domain, IPR027246=Eukaryotic porin/Tom40" CG12157 16-Dec-15 2015_12 "ENSDARG00000018425(tomm40),ENSDARG00000036721(tomm40l)" YMR203W(TOM40) WBGene00007686(tomm-40) ENSXETG00000019319(tomm40) "ENSMUSG00000002984(Tomm40),ENSMUSG00000005674(Tomm40l)" "ENSG00000130204(TOMM40),ENSG00000158882(TOMM40L)" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263334 CR43415 http://flybase.net/reports/FBgn0263334.html non_protein_coding_gene lincRNA.319 CR43415 16-Dec-15 2015_12 FBgn0027304 l(1)G0121 lethal (1) G0121 http://flybase.net/reports/FBgn0027304.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0041211 H23-14 H23-14 http://flybase.net/reports/FBgn0041211.html gene 16-Dec-15 2015_12 auxotroph FBgn0033591 CG13216 http://flybase.net/reports/FBgn0033591.html protein_coding_gene CG13216 16-Dec-15 2015_12 viable FBgn0000830 fs(1)M11 female sterile (1) M11 http://flybase.net/reports/FBgn0000830.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0040127 l(2)23CDa lethal (2) 23CDa http://flybase.net/reports/FBgn0040127.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010934 l(3)09291 lethal (3) 09291 http://flybase.net/reports/FBgn0010934.html gene P1736 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0038640 CG7706 http://flybase.net/reports/FBgn0038640.html protein_coding_gene 0017107=anion exchanger adaptor activity "IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG7706 16-Dec-15 2015_12 ENSDARG00000034160(slc4a1ap) ENSXETG00000022503(SLC4A1AP) ENSMUSG00000029141(Slc4a1ap) ENSG00000163798(SLC4A1AP) viable FBgn0053818 His3:CG33818 His3:CG33818 http://flybase.net/reports/FBgn0053818.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33818 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33818 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0002523 lacquered lacquered http://flybase.net/reports/FBgn0002523.html gene lac 16-Dec-15 2015_12 "fertile,reduced,viable,eye color defective,body color defective,visible,recessive" "macrochaeta,eye,wing" FBgn0264724 CR43992 http://flybase.net/reports/FBgn0264724.html non_protein_coding_gene lincRNA.567 CR43992 16-Dec-15 2015_12 FBgn0060303 l(3)SzB87Da lethal (3) SzB87Da http://flybase.net/reports/FBgn0060303.html gene "0074/03, 0098/05, 1132/08" 16-Dec-15 2015_12 "lethal,recessive" FBgn0011921 tRNA:M3:46A transfer RNA:met3:46A http://flybase.net/reports/FBgn0011921.html "FBgn0050003, FBgn0050262, FBgn0060138" tRNA_gene "0033436=AUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:met3:46A, CR30003, CR30262, tRNA[Met-ATG], tRNA:M:CAT:AE002787-c, chr2R.trna13-MetCAT, AE002787.trna31-MetCAT, tRNA:met:46A" CR30003 16-Dec-15 2015_12 FBgn0020633 Mcm7 Minichromosome maintenance 7 http://flybase.net/reports/FBgn0020633.html FBgn0025980 protein_coding_gene "0005524=ATP binding, 0003682=chromatin binding, 0003677=DNA binding, 0043138=3'-5' DNA helicase activity" "0006270=DNA replication initiation, 0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0007095=mitotic G2 DNA damage checkpoint" "0005656=nuclear pre-replicative complex, 0005875=microtubule associated complex, 0042555=MCM complex, 0005634=nucleus" "DmeMCM7, anon-EST:Liang-1.66, minichromosome maintenance 7, dMcm7, PCR1, McM7, CG4978, mcm7, MCM7, DmMCM7, Mcp-PCR1, clone 1.66, Minichromosome maintenance-PCR1" "IPR027925=MCM N-terminal domain, IPR031327=Mini-chromosome maintenance protein, IPR003593=AAA+ ATPase domain, IPR001208=MCM domain, IPR008050=DNA replication licensing factor Mcm7, IPR012340=Nucleic acid-binding, OB-fold, IPR018525=Mini-chromosome maintenance, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG4978 16-Dec-15 2015_12 ENSDARG00000035761(mcm7) YBR202W(MCM7) WBGene00003159(mcm-7) ENSXETG00000009104(mcm7) ENSMUSG00000029730(Mcm7) ENSG00000166508(MCM7) " embryonic stage | 0-4 hr , embryonic stage | stage 11-12 , egg stage | unfertilized egg , adult stage | female " " embryonic central nervous system

, unfertilized egg

" "viable,fertile,radiation sensitive" FBgn0028266 l(1)G0444 lethal (1) G0444 http://flybase.net/reports/FBgn0028266.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060668 l(3)S080301 lethal (3) S080301 http://flybase.net/reports/FBgn0060668.html gene 0803/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031739 CG14005 http://flybase.net/reports/FBgn0031739.html protein_coding_gene CG14005 16-Dec-15 2015_12 "viable,fertile" embryonic/larval salivary gland FBgn0058275 CG40275 http://flybase.net/reports/FBgn0058275.html FBan0040275 protein_coding_gene 16-Dec-15 2015_12 FBgn0002072 l(2)49Fa lethal (2) 49Fa http://flybase.net/reports/FBgn0002072.html gene "l(2)6, vr3, vr-3, l(2)vr3" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die,heat sensitive,non-suppressor of variegation,dominant" FBgn0085336 CG34307 http://flybase.net/reports/FBgn0085336.html protein_coding_gene CG34307 16-Dec-15 2015_12 FBgn0015937 emu emu http://flybase.net/reports/FBgn0015937.html gene 0003677=DNA binding bk36 16-Dec-15 2015_12 FBgn0267511 28SrRNA-ë¬:CR45851 28S ribosomal RNA pseudogene:CR45851 http://flybase.net/reports/FBgn0267511.html pseudogene_attribute CR45851 CR45851 16-Dec-15 2015_12 FBgn0003070 Pfd Pufdi http://flybase.net/reports/FBgn0003070.html gene 16-Dec-15 2015_12 "lethal,recessive" "wing,cold sensitive" FBgn0267603 CR45941 http://flybase.net/reports/FBgn0267603.html non_protein_coding_gene CR45941 16-Dec-15 2015_12 FBgn0037856 Leash Leash http://flybase.net/reports/FBgn0037856.html FBgn0052471 protein_coding_gene 0035330=regulation of hippo signaling 0031410=cytoplasmic vesicle "CG32471, CG4674, leash" "IPR014756=Immunoglobulin E-set, IPR011022=Arrestin C-terminal-like domain, IPR011021=Arrestin-like, N-terminal" CG4674 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,size defective" "neurite | pharate adult stage,wing" FBgn0027274 l(1)G0202 lethal (1) G0202 http://flybase.net/reports/FBgn0027274.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,female sterile" egg FBgn0038162 CG14368 http://flybase.net/reports/FBgn0038162.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC14830 K -0.838792933 1.29471163 0.301042628 0.123035314 1.724436304 0.751494515 FBgn0030782 CG18358 http://flybase.net/reports/FBgn0030782.html "FBgn0030781, FBgn0061408" protein_coding_gene "BcDNA:RE13557, CG9644" 16-Dec-15 2015_12 FBgn0031150 bves bves http://flybase.net/reports/FBgn0031150.html "FBgn0031153, FBgn0052513, FBgn0062860" protein_coding_gene 0016020=membrane "CG15448, CG1754, CG32513, BcDNA:SD21670" "IPR014710=RmlC-like jelly roll fold, IPR006916=Popeye protein, IPR018490=Cyclic nucleotide-binding-like" CG32513 16-Dec-15 2015_12 ENSDARG00000058548(popdc1) "ENSXETG00000018064(POPDC2),ENSXETG00000024466(POPDC3)" ENSMUSG00000071317(Bves) ENSG00000112276(BVES) "lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage,hyperactive,conditional,chemical resistant,viable,fertile" FBgn0086081 snoRNA:Me28S-A30 http://flybase.net/reports/FBgn0086081.html snoRNA_gene "Me28S-Am30, CR34710" CR34710 16-Dec-15 2015_12 FBgn0038827 Fancd2 Fancd2 http://flybase.net/reports/FBgn0038827.html "FBgn0051192, FBgn0051194" protein_coding_gene "0036297=interstrand cross-link repair, 0006281=DNA repair, 0031573=intra-S DNA damage checkpoint" 0005634=nucleus "dmFANCD2, CG17269, FAD, CG31194, CG31192, FANCD2" "IPR016024=Armadillo-type fold, IPR029448=Fanconi anaemia protein FANCD2" CG17269 16-Dec-15 2015_12 ENSDARG00000053574(fancd2) WBGene00012767(fcd-2) ENSXETG00000003617(FANCD2) ENSMUSG00000034023(Fancd2) ENSG00000144554(FANCD2) "visible,chemical conditional,tumorigenic,chemical sensitive,viable,mitotic cell cycle defective,conditional,lethal - all die before end of pupal stage,some die during pupal stage" "eye,chemical conditional,trichogen cell,mesothoracic tergum" FBgn0020868 anon-R258 anon-R258 http://flybase.net/reports/FBgn0020868.html gene 2-R258 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0000896 fs(1)M103 female sterile (1) M103 http://flybase.net/reports/FBgn0000896.html gene 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0083088 hella hella http://flybase.net/reports/FBgn0083088.html gene 16-Dec-15 2015_12 FBgn0001802 l(1)Mc24 lethal (1) Mc24 http://flybase.net/reports/FBgn0001802.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065407 l(2)SH1579 lethal (2) SH1579 http://flybase.net/reports/FBgn0065407.html gene l(2)SH2 1579 16-Dec-15 2015_12 "lethal,recessive" FBgn0034282 Mapmodulin Mapmodulin http://flybase.net/reports/FBgn0034282.html FBgn0025202 protein_coding_gene "0019212=phosphatase inhibitor activity, 0008017=microtubule binding" "0007017=microtubule-based process, 0006913=nucleocytoplasmic transport" "0005634=nucleus, 0048471=perinuclear region of cytoplasm, 0005737=cytoplasm, 0005875=microtubule associated complex, 0005654=nucleoplasm, 0005783=endoplasmic reticulum" "CG5784, anon-fast-evolving-3A2, CT18148, anon-EST:fe3A2, CT42180" "IPR001611=Leucine-rich repeat, IPR003603=U2A'/phosphoprotein 32 family A, C-terminal" CG5784 16-Dec-15 2015_12 "ENSDARG00000023330(anp32b),ENSDARG00000006487(anp32a)" "WBGene00009367(F33H2.3),WBGene00020588(T19H12.2)" "ENSXETG00000009516(BC064864.1),ENSXETG00000010183(anp32b),ENSXETG00000007821(anp32a),ENSXETG00000015745(anp32e)" "ENSMUSG00000028333(Anp32b),ENSMUSG00000015749(Anp32e)" "ENSG00000136938(ANP32B),ENSG00000140350(ANP32A),ENSG00000143401(ANP32E),ENSG00000184701,ENSG00000139223(ANP32D)" viable embryonic/larval hemocyte | third instar larval stage FBgn0034201 CG17290 http://flybase.net/reports/FBgn0034201.html FBgn0047163 protein_coding_gene BcDNA:RE15976 IPR004011=GYR motif CG17290 16-Dec-15 2015_12 "viable,planar polarity defective,partially lethal - majority die,some die during pupal stage" FBgn0014156 e(y)7 enhancer of yellow 7 http://flybase.net/reports/FBgn0014156.html gene 16-Dec-15 2015_12 FBgn0050406 tRNA:CR30406 transfer RNA:CR30406 http://flybase.net/reports/FBgn0050406.html "FBgn0011873, FBgn0050204, FBgn0060214" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033463=GGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:gly:58AB, tRNA:G:58AB, tRNA[Gly][[GGA]], CR30406, tRNA:G:TCC:AE002575-a, tRNA:gly:58AB, chr2R.trna54-GlyTCC, CR30204, AE002575.trna10-GlyTCC" CR30406 16-Dec-15 2015_12 FBgn0038834 RpS30 Ribosomal protein S30 http://flybase.net/reports/FBgn0038834.html FBgn0025548 protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" 0022627=cytosolic small ribosomal subunit "anon-EST:Posey127, S30, Q9VDH8_DROME, CG15697" "IPR006846=Ribosomal protein S30, IPR029071=Ubiquitin-related domain" CG15697 16-Dec-15 2015_12 "ENSDARG00000043663(zgc:110695),ENSDARG00000014830(fau)" WBGene00004499(rps-30) ENSXETG00000026219(fau) ENSMUSG00000038274(Fau) ENSG00000149806(FAU) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC26355 EK -0.6136451 -0.848712464 0.400387375 -3.487692823 2.538829726 4.223686726 FBgn0038978 tHMG1 testis-enriched HMG-box-containing protein 1 http://flybase.net/reports/FBgn0038978.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity, 0042803=protein homodimerization activity" "0005737=cytoplasm, 0005634=nucleus, 0005705=polytene chromosome interband, 0000785=chromatin" "testis-enriched HMG-box-containing protein-1, thmg-1, CG7045, tHMG-1" IPR009071=High mobility group box domain CG7045 16-Dec-15 2015_12 "YMR072W(ABF2),YPR052C(NHP6A),YBR089C-A(NHP6B)" "ENSXETG00000007910(SOX30),ENSXETG00000023439()" viable FBgn0266047 CG44812 http://flybase.net/reports/FBgn0266047.html protein_coding_gene CG44812 16-Dec-15 2015_12 FBgn0011223 hall halley http://flybase.net/reports/FBgn0011223.html gene 0007286=spermatid development hal 16-Dec-15 2015_12 male sterile spermatid FBgn0031526 CG8838 http://flybase.net/reports/FBgn0031526.html FBgn0044746 protein_coding_gene anon-WO0140519.135 CG8838 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030733 UQCR-14 Ubiquinol-cytochrome c reductase 14 kDa subunit http://flybase.net/reports/FBgn0030733.html "FBgn0025544, FBgn0062937" protein_coding_gene 0008121=ubiquinol-cytochrome-c reductase activity "0045333=cellular respiration, 0006122=mitochondrial electron transport, ubiquinol to cytochrome c, 0007406=negative regulation of neuroblast proliferation" 0005750=mitochondrial respiratory chain complex III "Ucrh, anon-EST:Posey167, CG3560, UCR6, Ubiquinol-cytochrome c reductase 14 kDa protein, Ubiquinol-cytochrome c oxidoreductase 14 kDa, Ucrh 14KDa, Ubiquinol-cytochrome C reductase complex 14 kDa protein, BcDNA:RH44664" IPR003197=Cytochrome b-c1 complex subunit 7 CG3560 16-Dec-15 2015_12 ENSDARG00000011146(uqcrb) YDR529C(QCR7) WBGene00020181(T02H6.11) "ENSMUSG00000021520(Uqcrb),ENSMUSG00000021741(Gm5457)" ENSG00000156467(UQCRB) FBgn0001384 l(1)2Bp lethal (1) 2Bp http://flybase.net/reports/FBgn0001384.html gene 16-Dec-15 2015_12 lethal FBgn0044354 Quasimodo\env env http://flybase.net/reports/FBgn0044354.html transposable_element_gene cruiser\env "IPR012014=Retroelement-encoded protein, env-related" 16-Dec-15 2015_12 FBgn0002517 l(3)Sp17 lethal (3) Sp17 http://flybase.net/reports/FBgn0002517.html gene 16-Dec-15 2015_12 lethal FBgn0041845 E(Sev-CycE)A14 E(Sev-CycE)A14 http://flybase.net/reports/FBgn0041845.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052565 CR32565 http://flybase.net/reports/FBgn0052565.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0022977 rrpD reduced receptor potential D http://flybase.net/reports/FBgn0022977.html gene 16-Dec-15 2015_12 FBgn0060414 l(3)S129717 lethal (3) S129717 http://flybase.net/reports/FBgn0060414.html gene 1297/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0039843 CG15567 http://flybase.net/reports/FBgn0039843.html protein_coding_gene 16-Dec-15 2015_12 FBgn0013465 grdf grooming defective http://flybase.net/reports/FBgn0013465.html gene 0007625=grooming behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0011891 tRNA:K2:42Ae transfer RNA:lys2:42Ae http://flybase.net/reports/FBgn0011891.html "FBgn0003795, FBgn0011886, FBgn0052837, FBgn0060185" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna100-LysCTT, tRNA[Lys][[2]], AE002769.trna9-LysCTT, tRNA:K2, tRNA:lys2:42Ae, tRNAlys, CR32837, 35SLys, tRNA:K:CTT:AE002769-d" CR32837 16-Dec-15 2015_12 FBgn0266822 CR45284 http://flybase.net/reports/FBgn0266822.html non_protein_coding_gene CR45284 16-Dec-15 2015_12 FBgn0016819 l(1)L6 lethal (1) L6 http://flybase.net/reports/FBgn0016819.html gene L6 16-Dec-15 2015_12 "lethal,recessive" FBgn0029817 CG15764 http://flybase.net/reports/FBgn0029817.html FBgn0063727 protein_coding_gene BcDNA:AT16792 CG15764 16-Dec-15 2015_12 viable FBgn0010796 l(3)03346 lethal (3) 03346 http://flybase.net/reports/FBgn0010796.html gene l(3)03347 16-Dec-15 2015_12 "lethal,recessive" FBgn0267419 CR45772 http://flybase.net/reports/FBgn0267419.html pseudogene_attribute CR45772 16-Dec-15 2015_12 FBgn0001753 l(1)jl lethal (1) jawless http://flybase.net/reports/FBgn0001753.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" cephalopharyngeal skeleton FBgn0001114 Glt Glutactin http://flybase.net/reports/FBgn0001114.html protein_coding_gene "0005509=calcium ion binding, 0052689=carboxylic ester hydrolase activity" "0016201=synaptic target inhibition, 0098542=defense response to other organism, 0008045=motor neuron axon guidance" 0005604=basement membrane "CG9280, CT26441, glutactin" "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site" CG9280 16-Dec-15 2015_12 embryonic stage " dorsal neurohemal organ

, embryonic central nervous system

, apodeme

" "immune response defective,viable,short lived,conditional" FBgn0266438 CG45068 http://flybase.net/reports/FBgn0266438.html protein_coding_gene "0000030=mannosyltransferase activity, 0000026=alpha-1,2-mannosyltransferase activity" 0006506=GPI anchor biosynthetic process 0005783=endoplasmic reticulum CG3419 IPR005599=GPI mannosyltransferase CG45068 16-Dec-15 2015_12 FBgn0040923 CG11368 http://flybase.net/reports/FBgn0040923.html FBgn0062915 protein_coding_gene BcDNA:RH67809 CG11368 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0051793 CG31793 http://flybase.net/reports/FBgn0051793.html "FBgn0032736, FBgn0032737" protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0006810=transport, 0055085=transmembrane transport" 0043190=ATP-binding cassette (ABC) transporter complex "CG17338, CG10441" "IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR003439=ABC transporter-like" CG31793 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) "viable,visible" trichogen cell FBgn0086359 Invadolysin Invadolysin http://flybase.net/reports/FBgn0086359.html "FBgn0082644, FBgn0002478, FBgn0037793" protein_coding_gene "0008233=peptidase activity, 0004222=metalloendopeptidase activity" "1902769=regulation of choline O-acetyltransferase activity, 0019915=lipid storage, 0022900=electron transport chain, 0006338=chromatin remodeling, 0008406=gonad development, 0051225=spindle assembly, 0051298=centrosome duplication, 0007052=mitotic spindle organization, 0007076=mitotic chromosome condensation, 0008354=germ cell migration, 0007420=brain development, 0007100=mitotic centrosome separation, 0007444=imaginal disc development, 0007155=cell adhesion, 0045842=positive regulation of mitotic metaphase/anaphase transition" "0016020=membrane, 0031252=cell leading edge, 0005737=cytoplasm" "DmIX-14, invadolysin, inv, l(3)SG34, CG3953, lethal (3) IX-14, IX-14, l(3)IX-14" "IPR001577=Peptidase M8, leishmanolysin" CG3953 16-Dec-15 2015_12 ENSDARG00000061265(LOC560606) WBGene00012796(Y43F4A.1) ENSMUSG00000022802(Lmln) ENSG00000185621(LMLN) FBgn0085464 CG34435 http://flybase.net/reports/FBgn0085464.html "FBan0015780, FBgn0029776" protein_coding_gene "0042623=ATPase activity, coupled" 0032504=multicellular organism reproduction "0005615=extracellular space, 0016459=myosin complex" CG15780 IPR011992=EF-hand domain pair CG34435 16-Dec-15 2015_12 FBgn0053986 CG33986 http://flybase.net/reports/FBgn0053986.html "FBgn0036506, FBgn0036507" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "FBgn0036507, CG7973, CG17014" IPR002557=Chitin binding domain CG33986 16-Dec-15 2015_12 FBgn0260106 2L1668 http://flybase.net/reports/FBgn0260106.html gene 16-Dec-15 2015_12 "nucleus & terminal tracheal cell | somatic clone,embryonic/larval tracheal system,somatic clone" FBgn0004845 l(3)88Bc lethal (3) 88Bc http://flybase.net/reports/FBgn0004845.html gene l(3)M41 16-Dec-15 2015_12 "lethal,recessive" FBgn0266361 CR45009 http://flybase.net/reports/FBgn0266361.html non_protein_coding_gene CR45009 16-Dec-15 2015_12 FBgn0052676 CG32676 http://flybase.net/reports/FBgn0052676.html "FBgn0030227, FBgn0030233" protein_coding_gene 0046331=lateral inhibition 0005654=nucleoplasm "CG9725, CG9732" "IPR000626=Ubiquitin domain, IPR029071=Ubiquitin-related domain" CG32676 16-Dec-15 2015_12 "ENSDARG00000018524(midn),ENSDARG00000067816" ENSMUSG00000035621(Midn) ENSG00000167470(MIDN) "viable,fertile,lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0001593 l(1)carot10 lethal (1) carot10 http://flybase.net/reports/FBgn0001593.html gene 16-Dec-15 2015_12 lethal FBgn0267519 28SrRNA-ë¬:CR45859 28S ribosomal RNA pseudogene:CR45859 http://flybase.net/reports/FBgn0267519.html pseudogene_attribute CR45859 CR45859 16-Dec-15 2015_12 FBgn0052058 Ir67c Ionotropic receptor 67c http://flybase.net/reports/FBgn0052058.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG32058, DmelIR67c, ionotropic receptor 67c, IR67c" CG32058 16-Dec-15 2015_12 "viable,visible,fertile" "chaeta,supernumerary,mesothoracic tergum" FBgn0004990 chr chrome http://flybase.net/reports/FBgn0004990.html gene 16-Dec-15 2015_12 "body color defective,recessive" FBgn0030014 CG15337 http://flybase.net/reports/FBgn0030014.html protein_coding_gene CG15337 16-Dec-15 2015_12 viable FBgn0030433 mRpL49 mitochondrial ribosomal protein L49 http://flybase.net/reports/FBgn0030433.html FBgn0061404 protein_coding_gene "0003743=translation initiation factor activity, 0003735=structural constituent of ribosome" "0006413=translational initiation, 0032543=mitochondrial translation" 0005762=mitochondrial large ribosomal subunit "MRP-L49, BcDNA:RE35556, mRpl49, CG4647" "IPR007740=Ribosomal protein L49/IMG2, IPR001950=Translation initiation factor SUI1" CG4647 16-Dec-15 2015_12 WBGene00011247(R11D1.9) ENSMUSG00000007338(Mrpl49) ENSG00000149792(MRPL49) FBgn0085519 CG40798 http://flybase.net/reports/FBgn0085519.html FBan0040798 protein_coding_gene 16-Dec-15 2015_12 FBgn0065586 l(2)SH0911 lethal (2) SH0911 http://flybase.net/reports/FBgn0065586.html gene l(2)SH2 0911 16-Dec-15 2015_12 "lethal,recessive" FBgn0262618 Dif::Rel Dif::Rel http://flybase.net/reports/FBgn0262618.html engineered_fusion_gene Dif^Rel 16-Dec-15 2015_12 FBgn0030593 CG9512 http://flybase.net/reports/FBgn0030593.html protein_coding_gene "0008812=choline dehydrogenase activity, 0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity" "0055114=oxidation-reduction process, 0045455=ecdysteroid metabolic process" "CT26924, Dmel_CG9512" "IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG9512 16-Dec-15 2015_12 viable FBgn0065141 l(3)SH105 lethal (3) SH105 http://flybase.net/reports/FBgn0065141.html gene l(2)SH3 105 16-Dec-15 2015_12 "lethal,recessive" FBgn0265875 CR44664 http://flybase.net/reports/FBgn0265875.html non_protein_coding_gene lincRNA.1000 CR44664 16-Dec-15 2015_12 FBgn0065627 l(2)SH0793 lethal (2) SH0793 http://flybase.net/reports/FBgn0065627.html gene l(2)SH2 0793 16-Dec-15 2015_12 "lethal,recessive" FBgn0000113 arch arch http://flybase.net/reports/FBgn0000113.html gene 16-Dec-15 2015_12 "visible,recessive" wing FBgn0016039 mpl-1 male prothoracic leg 1 http://flybase.net/reports/FBgn0016039.html gene MPL-1 16-Dec-15 2015_12 FBgn0062449 CG13197 http://flybase.net/reports/FBgn0062449.html FBgn0033647 protein_coding_gene "0008138=protein tyrosine/serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" 0006470=protein dephosphorylation BcDNA:RE27552 "IPR000387=Tyrosine specific protein phosphatases domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site" CG13197 16-Dec-15 2015_12 ENSDARG00000038156(dusp11) WBGene00010037(F54C8.4) ENSMUSG00000030002(Dusp11) ENSG00000144048(DUSP11) viable FBgn0025788 anon-17Ae anon-17Ae http://flybase.net/reports/FBgn0025788.html gene 16-Dec-15 2015_12 FBgn0016813 l(1)L15 lethal (1) L15 http://flybase.net/reports/FBgn0016813.html gene L15 16-Dec-15 2015_12 "lethal,recessive" FBgn0067389 c601 c601 http://flybase.net/reports/FBgn0067389.html gene 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0051181 CG31181 http://flybase.net/reports/FBgn0051181.html FBgn0046804 protein_coding_gene BcDNA:GH06646 16-Dec-15 2015_12 FBgn0013664 ms(3)303 ms(3)303 http://flybase.net/reports/FBgn0013664.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive,male sterile" FBgn0035943 CG5653 http://flybase.net/reports/FBgn0035943.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR002937=Amine oxidase CG5653 16-Dec-15 2015_12 viable FBgn0032100 CG13108 http://flybase.net/reports/FBgn0032100.html protein_coding_gene CG13108 16-Dec-15 2015_12 viable FBgn0021849 l(2)k14614 lethal (2) k14614 http://flybase.net/reports/FBgn0021849.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030704 CG15916 http://flybase.net/reports/FBgn0030704.html FBgn0061384 protein_coding_gene 0006364=rRNA processing BcDNA:RH08992 "IPR000238=Ribosome-binding factor A, IPR023799=Ribosome-binding factor A domain, IPR015946=K homology domain-like, alpha/beta" CG15916 16-Dec-15 2015_12 ENSMUSG00000024570(1110032A13Rik) ENSG00000101546(RBFA) viable FBgn0001789 l(1)Mb8 lethal (1) Mb8 http://flybase.net/reports/FBgn0001789.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035571 CG12493 http://flybase.net/reports/FBgn0035571.html protein_coding_gene "0035197=siRNA binding, 0003725=double-stranded RNA binding" 0005634=nucleus cg12493 IPR014720=Double-stranded RNA-binding domain CG12493 16-Dec-15 2015_12 "viable,male fertile" FBgn0020365 anon-15ABa anon-15ABa http://flybase.net/reports/FBgn0020365.html gene 548 16-Dec-15 2015_12 FBgn0267128 CR45568 http://flybase.net/reports/FBgn0267128.html non_protein_coding_gene CR45568 16-Dec-15 2015_12 FBgn0033206 DCTN4-p62 "Dynactin 4, p62 subunit" http://flybase.net/reports/FBgn0033206.html protein_coding_gene "0007018=microtubule-based movement, 0022008=neurogenesis" 0005869=dynactin complex "P62 DYNACTIN, p62, CG12042, p62 subunit of dynactin" IPR008603=Dynactin subunit 4 CG12042 16-Dec-15 2015_12 ENSDARG00000023988(dctn4) WBGene00016124(dnc-4) ENSMUSG00000024603(Dctn4) ENSG00000132912(DCTN4) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" FBgn0034094 Tsf3 Transferrin 3 http://flybase.net/reports/FBgn0034094.html protein_coding_gene 0005381=iron ion transmembrane transporter activity 0009617=response to bacterium 0005615=extracellular space "CG3666, Transferrin, tsf3" "IPR016357=Transferrin, IPR001156=Transferrin-like domain" CG3666 16-Dec-15 2015_12 "viable,locomotor rhythm defective" FBgn0032603 CG17928 http://flybase.net/reports/FBgn0032603.html FBgn0062205 protein_coding_gene 0016491=oxidoreductase activity "0046331=lateral inhibition, 0006629=lipid metabolic process" 0016021=integral component of membrane anon-WO0118547.16 "IPR012171=Fatty acid desaturase, IPR001199=Cytochrome b5-like heme/steroid binding domain, IPR005804=Fatty acid desaturase domain" CG17928 16-Dec-15 2015_12 "ENSMUSG00000075217(4833423E24Rik),ENSMUSG00000010663(Fads1),ENSMUSG00000024665(Fads2),ENSMUSG00000024664(Fads3)" "ENSG00000149485(FADS1),ENSG00000221968(FADS3),ENSG00000134824(FADS2),ENSG00000214876" "viable,visible" "chaeta,supernumerary" FBgn0060518 l(3)S103414 lethal (3) S103414 http://flybase.net/reports/FBgn0060518.html gene 1034/14 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0262887 CR43242 http://flybase.net/reports/FBgn0262887.html non_protein_coding_gene CR43242 16-Dec-15 2015_12 FBgn0032124 CG17855 http://flybase.net/reports/FBgn0032124.html protein_coding_gene CG17855 16-Dec-15 2015_12 viable FBgn0017545 RpS3A Ribosomal protein S3A http://flybase.net/reports/FBgn0017545.html "FBgn0002630, FBgn0013757" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0048477=oogenesis, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0022626=cytosolic ribosome, 0022627=cytosolic small ribosomal subunit" "RpS3a, RPS3a, l(4)102ABa, ribosomal protein S3alpha, ribosomal protein S3a, C3, Clone 3, Minute(4)101, Rsp3A, M(4)[57g], chr4:86830..87021, chr4:87101..87234, CG2168, M(4)101, chr4:87503..87595, anon-EST:Liang-2.29, M57g, RPS3A, Rps3A, clone 2.29, M(4)57g, M[57g]" "IPR001593=Ribosomal protein S3Ae, IPR018281=Ribosomal protein S3Ae, conserved site, IPR027500=40S ribosomal protein S1/3, eukaryotes" CG2168 16-Dec-15 2015_12 ENSDARG00000035692(rps3a) "YLR441C(RPS1A),YML063W(RPS1B)" WBGene00004470(rps-1) ENSXETG00000009396(rps3a) "ENSMUSG00000028081(Rps3a),ENSMUSG00000062611(Gm10119),ENSMUSG00000059751(Gm9000)" ENSG00000145425(RPS3A) " embryonic stage | stage 1-11 , adult stage | male , embryonic stage&&larval stage , adult stage | female "

ubiquitous "developmental rate defective,dominant,visible,Minute,size defective,lethal - all die before end of larval stage,recessive,some die during larval stage,female sterile,heat sensitive,lethal" "macrochaeta,adult heart,adult,egg chamber,heat sensitive,nurse cell,follicle cell" DRSC17168 EK -1.086216543 -0.589509061 1.878426332 -2.574878617 0.835754937 3.25600388 FBgn0264427 CR43845 http://flybase.net/reports/FBgn0264427.html non_protein_coding_gene CR43845 16-Dec-15 2015_12 FBgn0038727 CG7432 http://flybase.net/reports/FBgn0038727.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "c-SP19, SP19" "IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG7432 16-Dec-15 2015_12 "ENSXETG00000006287(),ENSXETG00000006296(BC087611.1),ENSXETG00000006281(),ENSXETG00000006294(TGas071o04.1),ENSXETG00000025971(),ENSXETG00000006282(),ENSXETG00000006285(),ENSXETG00000020742(tpsg1),ENSXETG00000020735(BC088892.1)" "ENSMUSG00000061259(Tmprss11d),ENSMUSG00000061184(Tmprss11c),ENSMUSG00000079451(9930032O22Rik),ENSMUSG00000035861(Tmprss11bnl),ENSMUSG00000072845(Tmprss11a)" "ENSG00000153802(TMPRSS11D),ENSG00000187054(TMPRSS11A),ENSG00000198092(TMPRSS11F),ENSG00000173487,ENSG00000087128(TMPRSS11E),ENSG00000185873(TMPRSS11B)" viable FBgn0085596 CG41280 http://flybase.net/reports/FBgn0085596.html FBan0041280 protein_coding_gene 16-Dec-15 2015_12 FBgn0014080 anon-15Aa anon-15Aa http://flybase.net/reports/FBgn0014080.html gene gene x 16-Dec-15 2015_12 FBgn0065229 l(2)SH2184 lethal (2) SH2184 http://flybase.net/reports/FBgn0065229.html gene l(2)SH2 2184 16-Dec-15 2015_12 "lethal,recessive" FBgn0014223 l(2)31Eb lethal (2) 31Eb http://flybase.net/reports/FBgn0014223.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001241 hy humpy http://flybase.net/reports/FBgn0001241.html gene 16-Dec-15 2015_12 "viable,reduced,female sterile,male sterile" adult thorax FBgn0038166 CG9588 http://flybase.net/reports/FBgn0038166.html protein_coding_gene "0006974=cellular response to DNA damage stimulus, 0006508=proteolysis" 0005838=proteasome regulatory particle "dp27, 9588, p27" IPR001478=PDZ domain CG9588 16-Dec-15 2015_12 ENSDARG00000006300(zgc:92643) YIL007C(NAS2) WBGene00016623(C44B7.1) ENSXETG00000003768(psmd9) ENSMUSG00000029440(Psmd9) ENSG00000110801(PSMD9) viable FBgn0267470 CR45820 http://flybase.net/reports/FBgn0267470.html non_protein_coding_gene CR45820 16-Dec-15 2015_12 FBgn0060415 l(3)S129615 lethal (3) S129615 http://flybase.net/reports/FBgn0060415.html gene 1296/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040734 CG15065 http://flybase.net/reports/FBgn0040734.html protein_coding_gene 0006952=defense response 0005615=extracellular space "IM2-like, CT34936" IPR013172=Immune-induced protein Dim CG15065 16-Dec-15 2015_12 viable FBgn0265527 CR44377 http://flybase.net/reports/FBgn0265527.html non_protein_coding_gene lincRNA.329 CR44377 16-Dec-15 2015_12 FBgn0037057 CG10512 http://flybase.net/reports/FBgn0037057.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR003767=Malate/L-lactate dehydrogenase CG10512 16-Dec-15 2015_12 "WBGene00012149(VF13D12L.3),WBGene00009453(F36A2.3)" ENSXETG00000012341() "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0051706 CG31706 http://flybase.net/reports/FBgn0051706.html FBgn0063625 protein_coding_gene CG6528 CG31706 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0028400 Syt4 Synaptotagmin 4 http://flybase.net/reports/FBgn0028400.html protein_coding_gene "0005544=calcium-dependent phospholipid binding, 0001786=phosphatidylserine binding, 0000149=SNARE binding" "0046928=regulation of neurotransmitter secretion, 0048167=regulation of synaptic plasticity, 0016192=vesicle-mediated transport, 0007269=neurotransmitter secretion, 0031340=positive regulation of vesicle fusion, 0016079=synaptic vesicle exocytosis" "0016021=integral component of membrane, 0016324=apical plasma membrane, 0008021=synaptic vesicle, 0031594=neuromuscular junction, 0005886=plasma membrane, 0045211=postsynaptic membrane, 0031982=vesicle" "synaptotagmin 4, dsyt4, sytIV, CG10047, synaptotagmin IV, SYT4, D.Syt IV, Synaptotagmin IV, Syt IV, Syt4, syt 4, SytIV, syt4" "IPR000008=C2 domain, IPR001565=Synaptotagmin" CG10047 16-Dec-15 2015_12 "ENSDARG00000057913(syt11a),ENSDARG00000056105(syt11b),ENSDARG00000036505(syt4)" WBGene00004924(snt-4) ENSXETG00000015442(Q6DET6_XENTR) "ENSMUSG00000024261(Syt4),ENSMUSG00000068923(Syt11)" "ENSG00000132872(SYT4),ENSG00000132718(SYT11)" embryonic stage " neuron

, embryonic central nervous system

" adult stage neuron

"visible,neurophysiology defective,neuroanatomy defective,viable,fertile" "wing vein,neuromuscular junctionMhc.PW,NMJ bouton,neuromuscular junction,motor neuron,neuromuscular junctionrn16),neuromuscular junctionelav.PLu" FBgn0011609 l(1)I33d25 lethal (1) I33d25 http://flybase.net/reports/FBgn0011609.html FBgn0010206 gene l(1)33d25 16-Dec-15 2015_12 lethal FBgn0069300 agho aghino http://flybase.net/reports/FBgn0069300.html gene 16-Dec-15 2015_12 FBgn0038269 Rrp6 Rrp6 http://flybase.net/reports/FBgn0038269.html protein_coding_gene "0000166=nucleotide binding, 0008408=3'-5' exonuclease activity, 0003676=nucleic acid binding" "0010468=regulation of gene expression, 0006378=mRNA polyadenylation, 0071027=nuclear RNA surveillance" "0000176=nuclear exosome (RNase complex), 0005634=nucleus, 0005652=nuclear lamina, 0005730=nucleolus" "DmRrp6, rrp6, dRrp6, CG7292" "IPR012588=Exosome-associated factor Rrp6, N-terminal, IPR012337=Ribonuclease H-like domain, IPR002121=HRDC domain, IPR010997=HRDC-like, IPR002562=3'-5' exonuclease domain" CG7292 16-Dec-15 2015_12 ENSDARG00000037708(zgc:55695) YOR001W(RRP6) WBGene00000796(crn-3) ENSXETG00000006318(EXOSC10) ENSMUSG00000017264(Exosc10) ENSG00000171824(EXOSC10) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC16223 IE 3.429577469 0.542280039 2.092372413 -3.305690023 -1.276981611 0.64242152 FBgn0013472 l(1)11P11 lethal (1) 11P11 http://flybase.net/reports/FBgn0013472.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg" FBgn0036934 sNPF-R short neuropeptide F receptor http://flybase.net/reports/FBgn0036934.html FBgn0044367 protein_coding_gene "0036400=short neuropeptide F receptor activity, 0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity, 0004983=neuropeptide Y receptor activity" "0070374=positive regulation of ERK1 and ERK2 cascade, 0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway, 2000253=positive regulation of feeding behavior, 0040018=positive regulation of multicellular organism growth" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "CG18639, GPCR60, neuropeptide-Y-receptor, sNPFR1, sNPFR, CG7395/CG18639, snpfr, CG7395, Drm-NPFR76F, CT22771, Neuropeptide F-like Receptor 76F, sNPF receptor, anon-WO0131005.1, NPFR76F, Short neuropeptide F receptor, Drm-sNPF-R" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000611=Neuropeptide Y receptor family" CG7395 16-Dec-15 2015_12 ENSDARG00000058120(LOC100002786) "WBGene00021983(Y58G8A.4),WBGene00013883(npr-13)" "ENSXETG00000024316(PRLHR),ENSXETG00000016004()" ENSMUSG00000045052(Prlhr) ENSG00000119973(PRLHR) "large body,feeding behavior defective,small body,viable" FBgn0039329 CG10669 http://flybase.net/reports/FBgn0039329.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG10669 16-Dec-15 2015_12 "viable,fertile" FBgn0261998 CG42816 http://flybase.net/reports/FBgn0261998.html "FBan0032186, FBgn0052186, FBgn0036753" protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0016887=ATPase activity" 0006810=transport 0016021=integral component of membrane "CG5944, CG32186, CG5587" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR026082=ABC transporter A, ABCA, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG42816 16-Dec-15 2015_12 FBgn0035815 Snmp2 Sensory neuron membrane protein 2 http://flybase.net/reports/FBgn0035815.html FBgn0035814 protein_coding_gene 0004888=transmembrane signaling receptor activity 0007155=cell adhesion "0016021=integral component of membrane, 0005886=plasma membrane" "148358_at, CG7422, SNMP2, CG16832" IPR002159=CD36 antigen CG7422 16-Dec-15 2015_12 viable FBgn0046633 anon-38E.24 anon-38E.24 http://flybase.net/reports/FBgn0046633.html gene 38E.24 16-Dec-15 2015_12 FBgn0005470 l(1)ts455b lethal (1) ts455b http://flybase.net/reports/FBgn0005470.html gene 16-Dec-15 2015_12 FBgn0030202 CG12640 http://flybase.net/reports/FBgn0030202.html protein_coding_gene CG12640 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0004487 l(1)air14 lethal aberrant immune response 14 http://flybase.net/reports/FBgn0004487.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0260033 siren7 siren 7 http://flybase.net/reports/FBgn0260033.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0032863 Cdc23 Cell division cycle 23 ortholog http://flybase.net/reports/FBgn0032863.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0090302=APC-Cdc20 complex activity" "0006909=phagocytosis, 0007113=endomitotic cell cycle, 0022008=neurogenesis, 0045842=positive regulation of mitotic metaphase/anaphase transition" 0005680=anaphase-promoting complex "Apc8, CG2508, Cdc23, 38C.54, CDC23, APC8, cdc23, CG2508-PA" "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR007192=Cdc23" CG2508 16-Dec-15 2015_12 ENSDARG00000044484(cdc23) YHR166C(CDC23) WBGene00003134(mat-3) ENSXETG00000006716(cdc23) ENSMUSG00000024370(Cdc23) ENSG00000094880(CDC23) "lethal,mitotic cell cycle defective,increased cell death,endomitotic cell cycle defective,somatic clone,neuroanatomy defective,viable,fertile" "melanotic mass | third instar larval stage,nucleus | somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC02708 I 2.692322675 1.116932439 0.602494993 -0.636278521 0.082502712 -0.581288585 FBgn0037101 CG7634 http://flybase.net/reports/FBgn0037101.html protein_coding_gene IPR011990=Tetratricopeptide-like helical domain CG7634 16-Dec-15 2015_12 viable FBgn0014292 l(3)64Bc lethal (3) 64Bc http://flybase.net/reports/FBgn0014292.html gene 16-Dec-15 2015_12 FBgn0259916 CG42445 http://flybase.net/reports/FBgn0259916.html protein_coding_gene CG7498 CG42445 16-Dec-15 2015_12 FBgn0262334 mir-992 mir-992 stem loop http://flybase.net/reports/FBgn0262334.html miRNA_gene "CR43041, miR-992, dme-mir-992" CR43041 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,wing" FBgn0015406 l(1)12Ba lethal (1) 12Ba http://flybase.net/reports/FBgn0015406.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037150 CG7133 http://flybase.net/reports/FBgn0037150.html protein_coding_gene IPR001623=DnaJ domain CG7133 16-Dec-15 2015_12 WBGene00001042(dnj-24) viable FBgn0265216 fs(2)Z2-2984 http://flybase.net/reports/FBgn0265216.html gene 16-Dec-15 2015_12 female sterile FBgn0030797 CG13004 http://flybase.net/reports/FBgn0030797.html protein_coding_gene CG13004 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0005523 l(2)52Dc lethal (2) 52Dc http://flybase.net/reports/FBgn0005523.html gene unnamed 16-Dec-15 2015_12 FBgn0267662 CR46000 http://flybase.net/reports/FBgn0267662.html non_protein_coding_gene CR46000 16-Dec-15 2015_12 FBgn0086669 snoRNA:ë¬18S-841a snoRNA:ë¬18S-841a http://flybase.net/reports/FBgn0086669.html "FBgn0065060, FBgn0083019, FBgn0053765" snoRNA_gene 0005730=nucleolus "CR33765, Psi18S-841a, Dm-66, snoRNA:66, snoR66, Psi 18S-841a(SnoR66), psi18S-841a, psi-18S-841a" CR33765 16-Dec-15 2015_12 FBgn0036235 CG6938 http://flybase.net/reports/FBgn0036235.html protein_coding_gene IPR007632=Anoctamin CG6938 16-Dec-15 2015_12 "ENSDARG00000036147(ano5b),ENSDARG00000015731,ENSDARG00000061544" YBR086C(IST2) WBGene00010138(F56A8.1) ENSXETG00000008392(ANO5) "ENSMUSG00000035189(Ano4),ENSMUSG00000074968" "ENSG00000151572(ANO4),ENSG00000134343(ANO3)" viable FBgn0263595 CR43617 http://flybase.net/reports/FBgn0263595.html non_protein_coding_gene Dm_3R:69251 CR43617 16-Dec-15 2015_12 FBgn0030222 CG9806 http://flybase.net/reports/FBgn0030222.html protein_coding_gene "0008237=metallopeptidase activity, 0004177=aminopeptidase activity, 0008270=zinc ion binding" "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005576=extracellular region "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain" CG9806 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0028628 ksh-19 ksh-19 http://flybase.net/reports/FBgn0028628.html gene 16-Dec-15 2015_12 FBgn0034329 IM1 Immune induced molecule 1 http://flybase.net/reports/FBgn0034329.html FBgn0062964 protein_coding_gene "0009617=response to bacterium, 0006952=defense response" 0005576=extracellular region "IM2-like, immune induced molecule 1, immune-induced molecule 1, BcDNA:RH08745, CG18108, DIM 1, DIM-1, Immune-induced peptide 1 precursor" IPR013172=Immune-induced protein Dim CG18108 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0040157 l(1)G0459 lethal (1) G0459 http://flybase.net/reports/FBgn0040157.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,female sterile" FBgn0019903 anon-14Bg anon-14Bg http://flybase.net/reports/FBgn0019903.html gene ORF 16-Dec-15 2015_12 FBgn0259528 B0097 http://flybase.net/reports/FBgn0259528.html gene 16-Dec-15 2015_12 visible wing FBgn0045032 usp::Cten\Usp-1 Usp-1 http://flybase.net/reports/FBgn0045032.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0001066 Fs(3)Tev Female sterile (3) Tevel http://flybase.net/reports/FBgn0001066.html gene "Fs(3)Tevel, Fs(3)Sz21" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0002937 ninaB neither inactivation nor afterpotential B http://flybase.net/reports/FBgn0002937.html FBgn0038171 protein_coding_gene "0003834=beta-carotene 15,15'-monooxygenase activity, 0004744=retinal isomerase activity, 0010436=carotenoid dioxygenase activity" "0016119=carotene metabolic process, 0007604=phototransduction, UV, 0009110=vitamin biosynthetic process, 0016063=rhodopsin biosynthetic process, 0042574=retinal metabolic process, 0007602=phototransduction, 0035238=vitamin A biosynthetic process, 0007603=phototransduction, visible light" "beta-diox, CG9347, anon-WO0148162.1, anon-WO0148163.1, beta-carotene dioxygenase, RPE65, DRPE65" IPR004294=Carotenoid oxygenase CG9347 16-Dec-15 2015_12 "ENSDARG00000009695,ENSDARG00000054420(LOC100004076),ENSDARG00000007480(rpe65a),ENSDARG00000055722(LOC100330576),ENSDARG00000027620(bcdo2l),ENSDARG00000041715(bco2a),ENSDARG00000029446" "WBGene00018755(bcmo-2),WBGene00012914(bcmo-1)" "ENSXETG00000012377(RPE65),ENSXETG00000026012(),ENSXETG00000002709(bcdo2)" "ENSMUSG00000028174(Rpe65),ENSMUSG00000032066(Bco2),ENSMUSG00000031845(Bcmo1)" "ENSG00000116745(RPE65),ENSG00000197580(BCO2),ENSG00000135697(BCMO1)" "neurophysiology defective,courtship behavior defective,male,phototaxis defective,viable" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,eye,rhabdomere" FBgn0028163 l(3)S034305 lethal (3) S034305 http://flybase.net/reports/FBgn0028163.html gene 0343/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262711 ifm(2)RS4 http://flybase.net/reports/FBgn0262711.html gene "0007527=adult somatic muscle development, 0060361=flight" 16-Dec-15 2015_12 "flightless,recessive" dorsal medial muscle FBgn0038285 CG6974 http://flybase.net/reports/FBgn0038285.html protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis 0017090=meprin A complex "IPR024079=Metallopeptidase, catalytic domain, IPR006026=Peptidase, metallopeptidase, IPR001506=Peptidase M12A, astacin" CG6974 16-Dec-15 2015_12 viable FBgn0082687 E(ftz)1819 E(ftz)1819 http://flybase.net/reports/FBgn0082687.html gene 1819 16-Dec-15 2015_12 FBgn0040173 l(1)G0344 lethal (1) G0344 http://flybase.net/reports/FBgn0040173.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0062676 EP2419 EP2419 http://flybase.net/reports/FBgn0062676.html gene EP(2)2419 16-Dec-15 2015_12 visible "eye,ommatidium" FBgn0060519 l(3)S102908 lethal (3) S102908 http://flybase.net/reports/FBgn0060519.html gene 1029/08 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041631 HSE Heat shock element http://flybase.net/reports/FBgn0041631.html regulatory_region 16-Dec-15 2015_12 FBgn0035103 Vdup1 Vitamin D3 up-regulated protein 1 http://flybase.net/reports/FBgn0035103.html protein_coding_gene "0007165=signal transduction, 0010629=negative regulation of gene expression" "0005634=nucleus, 0005737=cytoplasm" "vitamin D3 up-regulated protein 1, vitamin-D[[3]] upregulated protein 1, CG7047, vdup1, VDUP1, dvdup1, vitamin D[[3]] up-regulated protein 1" "IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain, IPR014756=Immunoglobulin E-set, IPR014752=Arrestin, C-terminal" CG7047 16-Dec-15 2015_12 viable FBgn0014070 Su(tor)3-91 Su(tor)3-91 http://flybase.net/reports/FBgn0014070.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036005 pall pallbearer http://flybase.net/reports/FBgn0036005.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0043652=engulfment of apoptotic cell, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "CG3428, Pallbearer, Pall, FBXO1" IPR001810=F-box domain CG3428 16-Dec-15 2015_12 ENSDARG00000027159(wu:fd49h06) ENSXETG00000018589(FBXO28) ENSMUSG00000047539(Fbxo28) ENSG00000143756(FBXO28) viable FBgn0015853 anon-10Cf anon-10Cf http://flybase.net/reports/FBgn0015853.html gene 16-Dec-15 2015_12 FBgn0039666 Diedel Diedel http://flybase.net/reports/FBgn0039666.html FBgn0047017 protein_coding_gene "0009617=response to bacterium, 0046426=negative regulation of JAK-STAT cascade" 0005615=extracellular space "CG11501, BcDNA:RH38110" IPR025061=Protein of unknown function DUF4002 CG11501 16-Dec-15 2015_12 viable DRSC14317 K 0.325148812 -0.317737346 0.171962994 0.517218706 -1.5835033 -1.148860884 FBgn0023430 l(3)69ABa lethal (3) 69ABa http://flybase.net/reports/FBgn0023430.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265951 CR44738 http://flybase.net/reports/FBgn0265951.html non_protein_coding_gene lincRNA.191 CR44738 16-Dec-15 2015_12 FBgn0036990 mRpL15 mitochondrial ribosomal protein L15 http://flybase.net/reports/FBgn0036990.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "l(3)77CDc, L15, 50S ribosomal protein L15, CG5219" "IPR005749=Ribosomal protein L15, bacterial-type, IPR021131=Ribosomal protein L18e/L15P, IPR030878=Ribosomal protein L15" CG5219 16-Dec-15 2015_12 ENSDARG00000041338(mrpl15) YNL284C(MRPL10) WBGene00022373(Y92H12BR.8) ENSXETG00000008103(MRPL15) ENSMUSG00000033845(Mrpl15) ENSG00000137547(MRPL15) "wild-type,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" trichogen cell FBgn0039609 CG14529 http://flybase.net/reports/FBgn0039609.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain" CG14529 16-Dec-15 2015_12 viable FBgn0024910 anon-16Fb anon-16Fb http://flybase.net/reports/FBgn0024910.html gene F-d 16-Dec-15 2015_12 FBgn0028225 l(3)S005343 lethal (3) S005343 http://flybase.net/reports/FBgn0028225.html gene 0053/43 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015415 l(1)15DFa lethal (1) 15DFa http://flybase.net/reports/FBgn0015415.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005253 l(3)SG72 lethal (3) SG72 http://flybase.net/reports/FBgn0005253.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005080 fs(2)OW804 female sterile (2) OW804 http://flybase.net/reports/FBgn0005080.html gene 16-Dec-15 2015_12 FBgn0038527 CG14324 http://flybase.net/reports/FBgn0038527.html FBgn0063033 protein_coding_gene BcDNA:RE34075 CG14324 16-Dec-15 2015_12 viable FBgn0065964 l(2)SH0023 lethal (2) SH0023 http://flybase.net/reports/FBgn0065964.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013505 l(1)R lethal (1) R http://flybase.net/reports/FBgn0013505.html gene 16-Dec-15 2015_12 lethal FBgn0013659 ms(2)neo4 ms(2)neo4 http://flybase.net/reports/FBgn0013659.html gene unnamed 16-Dec-15 2015_12 "male sterile,male semi-sterile,recessive" FBgn0001032 Fs(3)Bot Female sterile (3) Botond http://flybase.net/reports/FBgn0001032.html gene 0009792=embryo development ending in birth or egg hatching "Bot, Fs(3)Botond, Fs(3)Sz6" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0265459 Pten::Hsap\PTEN http://flybase.net/reports/FBgn0265459.html engineered_fusion_gene 16-Dec-15 2015_12 visible "eye,ommatidium" FBgn0082600 barfly barfly http://flybase.net/reports/FBgn0082600.html gene 0048149=behavioral response to ethanol "brf, F48" 16-Dec-15 2015_12 chemical resistant FBgn0060946 l(3)S037913 lethal (3) S037913 http://flybase.net/reports/FBgn0060946.html gene 0379/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0065268 l(2)SH2065 lethal (2) SH2065 http://flybase.net/reports/FBgn0065268.html gene l(2)SH2 2065 16-Dec-15 2015_12 "lethal,recessive" FBgn0000639 Fbp1 Fat body protein 1 http://flybase.net/reports/FBgn0000639.html protein_coding_gene 0008565=protein transporter activity 0015032=storage protein import into fat body 0005811=lipid particle "FBP-1, CG17285, P1, DmeFBP1, fbp-1, fat body protein-1, Fbp-1, fat body protein 1, LP07910p, FBP1, Protein-1, FbP1, fat body protein1, fbp1" "IPR014756=Immunoglobulin E-set, IPR013788=Hemocyanin/hexamerin, IPR005204=Hemocyanin, N-terminal, IPR005203=Hemocyanin, C-terminal" CG17285 16-Dec-15 2015_12 " prepupal stage , larval stage | third instar " "viable,visible" "chaeta,supernumerary" DRSC11166 IE -0.107803186 -2.742804636 -1.812833562 -0.040404357 -0.056758943 0.510452512 FBgn0019757 l(1)75B3 lethal (1) 75B3 http://flybase.net/reports/FBgn0019757.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040793 CG7630 http://flybase.net/reports/FBgn0040793.html "FBgn0027722, FBgn0027748, FBgn0062954" protein_coding_gene 0005811=lipid particle "anon-EST:Posey228, anon-EST:Posey153, BcDNA:RH19679" CG7630 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC10895 I -1.446533134 -1.849959914 -1.306958193 -0.683119007 -0.341451225 1.495704406 FBgn0001389 l(1)2Bu lethal (1) 2Bu http://flybase.net/reports/FBgn0001389.html gene "l(1)10-153-2, 10-153-2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0052151 CG32151 http://flybase.net/reports/FBgn0052151.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011135 l(1)Q210 lethal (1) Q210 http://flybase.net/reports/FBgn0011135.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0265106 CR44208 http://flybase.net/reports/FBgn0265106.html non_protein_coding_gene CR44208 16-Dec-15 2015_12 FBgn0053153 CG33153 http://flybase.net/reports/FBgn0053153.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003676 T-cp1 Tcp1-like http://flybase.net/reports/FBgn0003676.html FBgn0043836 protein_coding_gene "0005524=ATP binding, 0051082=unfolded protein binding, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0007052=mitotic spindle organization, 0006909=phagocytosis, 0006457=protein folding, 0090307=mitotic spindle assembly" "0005875=microtubule associated complex, 0005753=mitochondrial proton-transporting ATP synthase complex, 0005832=chaperonin-containing T-complex, 0005829=cytosol" "CG5374, gh05123, T-cpl, Tcp1-alpha, TCP1alpha, TCP-1alpha, T-complex 1, Tcp1, TCPA_DROME, T-CP1, Tcp1-like, BEST:GH05123, tcp1, Tcp-1, CCT1" "IPR012715=T-complex protein 1, alpha subunit, IPR002194=Chaperonin TCP-1, conserved site, IPR027413=GroEL-like equatorial domain, IPR027409=GroEL-like apical domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR027410=TCP-1-like chaperonin intermediate domain, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1)" CG5374 16-Dec-15 2015_12 ENSDARG00000017891(tcp1) YDR212W(TCP1) WBGene00000377(cct-1) ENSXETG00000021165(TCP1) ENSMUSG00000068039(Tcp1) ENSG00000120438(TCP1) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16877 E 1.426228757 -0.613398535 3.027004188 -0.751635585 -0.135714501 -0.566715079 FBgn0037464 CG1988 http://flybase.net/reports/FBgn0037464.html protein_coding_gene CG1988 16-Dec-15 2015_12 "viable,fertile" FBgn0265727 CR44534 http://flybase.net/reports/FBgn0265727.html non_protein_coding_gene lincRNA.972 CR44534 16-Dec-15 2015_12 FBgn0263887 l(3)D7 http://flybase.net/reports/FBgn0263887.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0011095 l(1)Q55 lethal (1) Q55 http://flybase.net/reports/FBgn0011095.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0001654 l(1)ds8 lethal (1) discs small 8 http://flybase.net/reports/FBgn0001654.html gene "l(1)d sml-8, l(1)d.sml.-8" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0002249 l(3)68Dc lethal (3) 68Dc http://flybase.net/reports/FBgn0002249.html gene "rose-gespleten region interval 10, l(3)rsg10, rsg10" 16-Dec-15 2015_12 lethal FBgn0053468 CG33468 http://flybase.net/reports/FBgn0053468.html protein_coding_gene CG33468 16-Dec-15 2015_12 viable FBgn0267865 CR46153 http://flybase.net/reports/FBgn0267865.html non_protein_coding_gene CR46153 16-Dec-15 2015_12 FBgn0014845 E(var)2-88 Enhancer of variegation 2-88 http://flybase.net/reports/FBgn0014845.html gene 16-Dec-15 2015_12 enhancer of variegation FBgn0250826 CG34160 http://flybase.net/reports/FBgn0250826.html "FBgn0085189, FBgn0045102" protein_coding_gene NEST:bs34b09 CG34160 16-Dec-15 2015_12 FBgn0267494 Mst77Y-8ë¬ Male-specific pseudogene 77Y 8 http://flybase.net/reports/FBgn0267494.html "FBgn0262757, FBgn0267421" pseudogene_attribute "Male-specific transcript 77Y 8, Mst77Y-8, CR45774" CR45774 16-Dec-15 2015_12 FBgn0065967 l(2)SH0008 lethal (2) SH0008 http://flybase.net/reports/FBgn0065967.html gene l(2)SH2 0008 16-Dec-15 2015_12 "lethal,recessive" FBgn0050106 CCHa1-R CCHamide-1 receptor http://flybase.net/reports/FBgn0050106.html "FBgn0034256, FBgn0034257" protein_coding_gene "0004946=bombesin receptor activity, 0008188=neuropeptide receptor activity, 0008261=allatostatin receptor activity" "0007218=neuropeptide signaling pathway, 0031989=bombesin receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "CG30106, ASB-receptor, CG18192, CCHamide1r, CCHa1r, CG14484" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR001556=Bombesin receptor, IPR017452=GPCR, rhodopsin-like, 7TM" CG30106 16-Dec-15 2015_12 "ENSDARG00000054152,ENSDARG00000056620(grpr)" "ENSXETG00000016350(NMBR),ENSXETG00000019750(BRS3)" "ENSMUSG00000031364(Grpr),ENSMUSG00000019865(Nmbr),ENSMUSG00000031130(Brs3)" "ENSG00000126010(GRPR),ENSG00000135577(NMBR),ENSG00000102239(BRS3)" "viable,fertile" FBgn0046302 CG10650 http://flybase.net/reports/FBgn0046302.html FBgn0032735 protein_coding_gene BEST:GH09876 IPR008472=Domain of unknown function DUF753 CG10650 16-Dec-15 2015_12 "viable,fertile" FBgn0051295 CG31295 http://flybase.net/reports/FBgn0051295.html FBgn0062868 protein_coding_gene BcDNA:SD17750 16-Dec-15 2015_12 FBgn0065787 l(2)SH0433 lethal (2) SH0433 http://flybase.net/reports/FBgn0065787.html gene l(2)SH2 0433 16-Dec-15 2015_12 "lethal,recessive" FBgn0042111 CG18766 http://flybase.net/reports/FBgn0042111.html FBgn0039499 protein_coding_gene CG5995 IPR026095=Myb/SANT-like DNA-binding domain-containing protein CG18766 16-Dec-15 2015_12 viable FBgn0034142 CG8306 http://flybase.net/reports/FBgn0034142.html protein_coding_gene "0050062=long-chain-fatty-acyl-CoA reductase activity, 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity" 0010025=wax biosynthetic process "0005777=peroxisome, 0012505=endomembrane system" "IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase, IPR016040=NAD(P)-binding domain" CG8306 16-Dec-15 2015_12 lethal FBgn0013474 l(1)12P3 lethal (1) 12P3 http://flybase.net/reports/FBgn0013474.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0265342 CG44296 http://flybase.net/reports/FBgn0265342.html protein_coding_gene 0004129=cytochrome-c oxidase activity IPR004202=Cytochrome c oxidase subunit VIIc CG44296 16-Dec-15 2015_12 FBgn0020263 oro oroshigane http://flybase.net/reports/FBgn0020263.html FBgn0015693 gene 0005886=plasma membrane "E(B)2A, Enhancer of Bar 2A" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/first instar larval cuticle,egg" FBgn0002574 lys lysine http://flybase.net/reports/FBgn0002574.html gene 16-Dec-15 2015_12 fat body FBgn0014455 Ahcy13 Adenosylhomocysteinase at 13 http://flybase.net/reports/FBgn0014455.html protein_coding_gene 0004013=adenosylhomocysteinase activity 0006730=one-carbon metabolic process "SAHH, CG11654, AdoHcyase, ahcY, S-Adenosyl-L-homocysteine hydrolase" "IPR000043=Adenosylhomocysteinase, IPR016040=NAD(P)-binding domain, IPR015878=S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR020082=S-adenosyl-L-homocysteine hydrolase, conserved site" CG11654 16-Dec-15 2015_12 ENSDARG00000005191(ahcy) YER043C(SAH1) WBGene00019322(ahcy-1) ENSXETG00000019486(ahcy) ENSMUSG00000027597(Ahcy) ENSG00000101444(AHCY) embryonic stage -- adult stage viable FBgn0035008 CG3494 http://flybase.net/reports/FBgn0035008.html protein_coding_gene 0006909=phagocytosis CT11751 IPR001611=Leucine-rich repeat CG3494 16-Dec-15 2015_12 ENSXETG00000012852() viable FBgn0264441 CR43859 http://flybase.net/reports/FBgn0264441.html non_protein_coding_gene CR43859 16-Dec-15 2015_12 FBgn0034674 CG9304 http://flybase.net/reports/FBgn0034674.html protein_coding_gene "0019236=response to pheromone, 0007186=G-protein coupled receptor signaling pathway" "IPR019336=Intimal thickness related receptor, IRP" CG9304 16-Dec-15 2015_12 WBGene00011441(T04F8.2) viable FBgn0011905 tRNA:K5:87BC transfer RNA:lys5:87BC http://flybase.net/reports/FBgn0011905.html "FBgn0003793, FBgn0011901, FBgn0051197, FBgn0060171" tRNA_gene "0033443=AAA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:lys5:87BC, tRNA:K5, tRNA:K:TTT:AE002708, CR31197, AE002708.trna3-LysTTT, chr3R.trna9-LysTTT" CR31197 16-Dec-15 2015_12 FBgn0016849 l(1)N30 lethal (1) N30 http://flybase.net/reports/FBgn0016849.html gene N30 16-Dec-15 2015_12 "lethal,recessive" FBgn0002607 RpL19 Ribosomal protein L19 http://flybase.net/reports/FBgn0002607.html "FBgn0010030, FBgn0022215, FBgn0025292" protein_coding_gene 0003735=structural constituent of ribosome "0000022=mitotic spindle elongation, 0006412=translation, 0051298=centrosome duplication" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "E(Dl)KP135, Rp L19, rpL19, M(2)60E, l(2)k03704, CG2746, ribosomal protein L19, M(2)a, anon-EST:Posey33, lethal (2) k03704, rpl19, M(2)c, L19, Enhancer of Delta KP135, M60E, Minute(2)60E, Rpl19" "IPR023638=Ribosomal protein L19/L19e conserved site, IPR015974=Ribosomal protein L19/L19e, domain 3, IPR000196=Ribosomal protein L19/L19e domain, IPR015972=Ribosomal protein L19/L19e, domain 1, IPR027547=Ribosomal protein L19/L19e" CG2746 16-Dec-15 2015_12 ENSDARG00000013307(rpl19) "YBL027W(RPL19B),YBR084C-A(RPL19A)" WBGene00004431(rpl-19) ENSXETG00000023711(Q6AZL5_XENTR) ENSMUSG00000017404(Rpl19) "ENSG00000108298(RPL19),ENSG00000218227" "lethal,recessive,visible,dominant,developmental rate defective,viable" macrochaeta DRSC04649 IEK -2.445740034 -1.638076225 0.659973874 -2.036295371 2.776347035 3.735108756 FBgn0001630 l(1)dn7 lethal (1) discs normal 7 http://flybase.net/reports/FBgn0001630.html gene l(1)d.norm.-7 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030207 CG2887 http://flybase.net/reports/FBgn0030207.html protein_coding_gene 0051082=unfolded protein binding "0006457=protein folding, 0009408=response to heat" "IPR001623=DnaJ domain, IPR002939=Chaperone DnaJ, C-terminal, IPR008971=HSP40/DnaJ peptide-binding, IPR018253=DnaJ domain, conserved site" CG2887 16-Dec-15 2015_12 YNL007C(SIS1) viable FBgn0014981 l(2)46Cb lethal (2) 46Cb http://flybase.net/reports/FBgn0014981.html gene "II, Group II" 16-Dec-15 2015_12 "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001220 Hsc70-5 Heat shock protein cognate 5 http://flybase.net/reports/FBgn0001220.html FBgn0022196 protein_coding_gene "0016887=ATPase activity, 0051082=unfolded protein binding, 0005524=ATP binding" "0070584=mitochondrion morphogenesis, 0009408=response to heat, 0010918=positive regulation of mitochondrial membrane potential, 0006457=protein folding, 0000422=mitochondrion degradation" "0005739=mitochondrion, 0005811=lipid particle, 0005875=microtubule associated complex" "l(2)k04907, hsc5, CG8542, Hsc5, Hsc70, HSC70-5, Hsp-c5, dhsc70, hsc-70-5, Heat shock 70 kDa protein cognate 5, HSC5, mortalin, Hsc-5, Mortalin, Heat Shock 70 kDa Protein Cognate 5, Hsp cognate 5, HSC-70, hsc70, hsc70-5, HSC70" "IPR013126=Heat shock protein 70 family, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR012725=Chaperone DnaK, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site" CG8542 16-Dec-15 2015_12 ENSDARG00000003035(hspa9) "YJR045C(SSC1),YEL030W(ECM10)" WBGene00002010(hsp-6) ENSXETG00000008404(HSPA9) ENSMUSG00000024359(Hspa9) ENSG00000113013(HSPA9) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,majority die during pupal stage,short lived,temperature conditional,locomotor rhythm defective,progressive,majority die during second instar larval stage,viable,majority die during third instar larval stage" mitochondrion DRSC07442 I -2.417277797 0.141278778 -0.61489733 -0.064526791 0.290182729 -0.38384767 FBgn0037301 Mms19 Mms19 http://flybase.net/reports/FBgn0037301.html FBgn0045375 protein_coding_gene 0006281=DNA repair "CG12005, mms19, dMMS19, NEST:bs07f08, MMS19" "IPR016024=Armadillo-type fold, IPR024687=MMS19, C-terminal" CG12005 16-Dec-15 2015_12 YIL128W(MET18) WBGene00016060(mms-19) ENSXETG00000003439(MMS19) ENSMUSG00000025159(Mms19) ENSG00000155229(MMS19) "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038598 CG7131 http://flybase.net/reports/FBgn0038598.html FBgn0044660 protein_coding_gene anon-WO0140519.212 CG7131 16-Dec-15 2015_12 ENSXETG00000025129(BC068219.1) "ENSMUSG00000038570(Fam154b),ENSMUSG00000028492(Fam154a)" "ENSG00000155875(FAM154A),ENSG00000188659(FAM154B)" FBgn0001221 Hsc70-6 Heat shock protein cognate 6 http://flybase.net/reports/FBgn0001221.html gene 0006457=protein folding "Hsc6, HSC70, HSC-70, hsc70, dhsc70, Hsc70, hsc6" 16-Dec-15 2015_12 FBgn0067872 Mod(Prat:bw)3-3 Mod(Prat:bw)3-3 http://flybase.net/reports/FBgn0067872.html gene Mod-3-3 16-Dec-15 2015_12 "lethal,recessive" FBgn0001701 l(1)ESHS22 lethal (1) ESHS22 http://flybase.net/reports/FBgn0001701.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266211 CR44906 http://flybase.net/reports/FBgn0266211.html pseudogene_attribute CR44906 16-Dec-15 2015_12 FBgn0051778 CG31778 http://flybase.net/reports/FBgn0051778.html "FBgn0031565, FBgn0047241, FBgn0063619" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity BcDNA:HL03084 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG31778 16-Dec-15 2015_12 viable FBgn0260324 GSd327 http://flybase.net/reports/FBgn0260324.html gene 16-Dec-15 2015_12 lethal FBgn0263512 Vsx2 Visual system homeobox 2 ortholog http://flybase.net/reports/FBgn0263512.html "FBgn0053980, FBgn0029772, FBgn0029773, FBgn0029774, FBtr0070788, FBpp0070754, FBtr0070789, FBpp0070755, FBgn0026558" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0001748=optic lobe placode development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "dChx2, Chx2, CG15781, CG33980, DChx2, CG15782, CG15783, dVsx2" "IPR003654=OAR domain, IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR023339=CVC domain" CG33980 16-Dec-15 2015_12 ENSXETG00000013302() ENSMUSG00000033080(Vsx1) ENSG00000004848(ARX) FBgn0010120 l(1)2Dc lethal (1) 2Dc http://flybase.net/reports/FBgn0010120.html gene l(1)405 16-Dec-15 2015_12 lethal FBgn0033573 Obp47a Odorant-binding protein 47a http://flybase.net/reports/FBgn0033573.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp47a, CG12944, 47a" IPR006170=Pheromone/general odorant binding protein CG12944 16-Dec-15 2015_12 viable FBgn0000067 ale almond eye http://flybase.net/reports/FBgn0000067.html gene 16-Dec-15 2015_12 "visible,recessive" eye FBgn0030958 CR6900 http://flybase.net/reports/FBgn0030958.html pseudogene_attribute CG6900 CR6900 16-Dec-15 2015_12 viable FBgn0033052 SCAP SREBP cleavage activating protein http://flybase.net/reports/FBgn0033052.html FBgn0033053 protein_coding_gene 0015485=cholesterol binding "0035103=sterol regulatory element binding protein cleavage, 0000042=protein targeting to Golgi, 0008203=cholesterol metabolic process, 0032933=SREBP signaling pathway, 0016485=protein processing" "0000139=Golgi membrane, 0016021=integral component of membrane, 0005789=endoplasmic reticulum membrane" "dscap, dScap, CG14592, dSCAP, Scap_Dm, CG8356, SCAP, Scap, CG33131" "IPR000731=Sterol-sensing domain, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR030225=Sterol regulatory element-binding protein cleavage-activating protein, IPR001680=WD40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG33131 16-Dec-15 2015_12 ENSDARG00000018096(LOC558292) WBGene00004744(scp-1) ENSXETG00000020354(SCAP) ENSMUSG00000032485(Scap) ENSG00000114650(SCAP) "viable,reduced,developmental rate defective" FBgn0046253 CG3502 http://flybase.net/reports/FBgn0046253.html FBgn0034847 protein_coding_gene "0008270=zinc ion binding, 0008237=metallopeptidase activity, 0004177=aminopeptidase activity" 0006508=proteolysis BEST:LD34564 "IPR024571=ERAP1-like C-terminal domain, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase" CG3502 16-Dec-15 2015_12 viable FBgn0266365 CR45013 http://flybase.net/reports/FBgn0266365.html non_protein_coding_gene CR45013 16-Dec-15 2015_12 FBgn0266364 CG45012 http://flybase.net/reports/FBgn0266364.html protein_coding_gene IPR002350=Kazal domain CG45012 16-Dec-15 2015_12 FBgn0031786 CG13989 http://flybase.net/reports/FBgn0031786.html FBgn0047349 protein_coding_gene BcDNA:AT09383 CG13989 16-Dec-15 2015_12 viable FBgn0052118 CG32118 http://flybase.net/reports/FBgn0052118.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0005034 er erupt http://flybase.net/reports/FBgn0005034.html gene 16-Dec-15 2015_12 visible "eye-antennal disc,eye,ommatidium" FBgn0020355 anon-2G10 anon-2G10 http://flybase.net/reports/FBgn0020355.html gene 2G10 16-Dec-15 2015_12 FBgn0261608 RpL37A Ribosomal protein L37A http://flybase.net/reports/FBgn0261608.html "FBgn0028696, FBgn0031680, FBgn0047015, FBgn0047145, FBgn0005510, FBgn0001921, FBgn0002596" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" 0022625=cytosolic large ribosomal subunit "DmL37a, M(2)S1, BcDNA:RH41593, CG5827, Ribosomal protein L37a, l(2)25Cb, chr2L:5071724..5071820, Minute (2) 25C, L37A, BcDNA:RE23595, RpL37a, M(2)25C" "IPR002674=Ribosomal protein L37ae, IPR011332=Zinc-binding ribosomal protein, IPR011331=Ribosomal protein L37ae/L37e" CG5827 16-Dec-15 2015_12 ENSDARG00000042389(LOC100330127) "YPR043W(RPL43A),YJR094W-A(RPL43B)" WBGene00004456(rpl-43) ENSXETG00000015468(Q6AZL0_XENTR) ENSMUSG00000046330(Rpl37a) ENSG00000197756(RPL37A) adult stage DRSC02899 IEK -2.225551478 -1.85433955 -1.508742041 -2.806904876 -0.293015328 2.057932251 FBgn0038474 mRpS11 mitochondrial ribosomal protein S11 http://flybase.net/reports/FBgn0038474.html FBgn0063651 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "BcDNA:RH70248, GH1, MRP-S11, CG5184" IPR001971=Ribosomal protein S11 CG5184 16-Dec-15 2015_12 ENSDARG00000036782 WBGene00012244(W04D2.5) ENSXETG00000007593(MRPS11) ENSMUSG00000030611(Mrps11) ENSG00000181991(MRPS11) FBgn0264575 Egfr::Hsap\EGFR http://flybase.net/reports/FBgn0264575.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0051321 CG31321 http://flybase.net/reports/FBgn0051321.html FBgn0062435 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane BcDNA:RH31685 "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG31321 16-Dec-15 2015_12 YJL163C() "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0039838 CG3669 http://flybase.net/reports/FBgn0039838.html protein_coding_gene "0004089=carbonate dehydratase activity, 0008270=zinc ion binding" 0006730=one-carbon metabolic process "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class, IPR018338=Carbonic anhydrase, alpha-class, conserved site" CG3669 16-Dec-15 2015_12 "ENSDARG00000043589(LOC100330944),ENSDARG00000044512(LOC100333339)" WBGene00000283(cah-5) "ENSXETG00000022384(),ENSXETG00000016426(CA14)" "ENSMUSG00000079715,ENSMUSG00000028463(Car9)" FBgn0267459 CR45809 http://flybase.net/reports/FBgn0267459.html non_protein_coding_gene CR45809 16-Dec-15 2015_12 FBgn0260012 pds5 http://flybase.net/reports/FBgn0260012.html "FBgn0033676, FBgn0062185, FBgn0086756, FBgn0021887" protein_coding_gene "0007062=sister chromatid cohesion, 0007059=chromosome segregation, 0030717=karyosome formation" "0005700=polytene chromosome, 0008278=cohesin complex, 0005634=nucleus" "pds5, lethal (2) k13312, CG17509, PDS5, Pds5, dPds5, cohiba, anon-WO0118547.183, l(2)k13312" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG17509 16-Dec-15 2015_12 "ENSDARG00000061312(pds5b),ENSDARG00000055022(pds5a)" WBGene00001352(evl-14) "ENSXETG00000017000(PDS5B),ENSXETG00000012823(PDS5A)" "ENSMUSG00000034021(Pds5b),ENSMUSG00000029202(Pds5a)" "ENSG00000083642(PDS5B),ENSG00000121892(PDS5A)" FBgn0065418 l(2)SH1531 lethal (2) SH1531 http://flybase.net/reports/FBgn0065418.html gene l(2)SH2 1531 16-Dec-15 2015_12 "lethal,recessive" FBgn0261885 osa osa http://flybase.net/reports/FBgn0261885.html "FBgn0003013, FBgn0010708, FBgn0011421, FBgn0015384, FBgn0046467, FBgn0062101, FBgn0259443" protein_coding_gene "0003713=transcription coactivator activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0046530=photoreceptor cell differentiation, 0016055=Wnt signaling pathway, 0007379=segment specification, 0014017=neuroblast fate commitment, 0008586=imaginal disc-derived wing vein morphogenesis, 0048190=wing disc dorsal/ventral pattern formation, 0042058=regulation of epidermal growth factor receptor signaling pathway, 0045893=positive regulation of transcription, DNA-templated, 0007476=imaginal disc-derived wing morphogenesis, 0007406=negative regulation of neuroblast proliferation, 0006357=regulation of transcription from RNA polymerase II promoter, 0008587=imaginal disc-derived wing margin morphogenesis, 0006338=chromatin remodeling" "0005634=nucleus, 0035060=brahma complex, 0005654=nucleoplasm" "eye lid, eyelid, Osa, E(E2F)3C, en(lz)4F/4H, anon-WO0172774.126, eld, anon-WO0118547.314, l(3)04539, l(3)00090, CG7467, l(3)j9C3, OSA, p300, C819" "IPR001606=ARID DNA-binding domain, IPR016024=Armadillo-type fold, IPR021906=SWI/SNF-like complex subunit BAF250/Osa" CG7467 16-Dec-15 2015_12 "ENSDARG00000003673(si:dkey-60a16.3),ENSDARG00000060073(LOC568161)" WBGene00002717(let-526) "ENSXETG00000020695(ARID1A),ENSXETG00000011226(ARID1B)" "ENSMUSG00000069729(Arid1b),ENSMUSG00000007880(Arid1a)" "ENSG00000117713(ARID1A),ENSG00000049618(ARID1B)" " larval stage , embryonic stage | early " " larval salivary gland

,

ubiquitous , morphogenetic furrow | anterior to

, eye disc

, dorsal mesothoracic disc

" DRSC03744 IE -0.083839134 -3.507738129 -0.47039841 1.688272232 FBgn0029809 CG15767 http://flybase.net/reports/FBgn0029809.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0006457=protein folding, 0000413=protein peptidyl-prolyl isomerization" "IPR029000=Cyclophilin-like domain, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain" CG15767 16-Dec-15 2015_12 viable DRSC29131 K 0.028478082 0.478489976 0.458077061 0.504459433 -1.94110309 0.176577654 FBgn0005022 dkl darker legs http://flybase.net/reports/FBgn0005022.html gene "thick legs darker, thl-d, thl[d], thick legs-darker" 16-Dec-15 2015_12 "viable,female fertile,poor,visible,reduced,body color defective" "eye,wing,leg,adult thorax,adult abdomen" FBgn0069219 gl(3R)53-6 gl(3R)53-6 http://flybase.net/reports/FBgn0069219.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal,germline clone,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment,embryonic abdominal segment" FBgn0032150 CG13123 http://flybase.net/reports/FBgn0032150.html protein_coding_gene 0008270=zinc ion binding 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG13123 16-Dec-15 2015_12 viable DRSC02219 IE 0.321201511 -1.692175389 -1.716207126 -0.003728123 -0.982427981 0.131021487 FBgn0021808 l(2)k16703 lethal (2) k16703 http://flybase.net/reports/FBgn0021808.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065462 l(2)SH1362 lethal (2) SH1362 http://flybase.net/reports/FBgn0065462.html gene l(2)SH2 1362 16-Dec-15 2015_12 "lethal,recessive" FBgn0266123 T:PACT-Plp PACT domain of Plp http://flybase.net/reports/FBgn0266123.html engineered_tag "T:PACT-cp309, PACT domain of cp309" 16-Dec-15 2015_12 FBgn0060541 l(3)S099908 lethal (3) S099908 http://flybase.net/reports/FBgn0060541.html gene 0999/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0265469 CG44362 http://flybase.net/reports/FBgn0265469.html protein_coding_gene CG44362 16-Dec-15 2015_12 FBgn0260468 CG7950 http://flybase.net/reports/FBgn0260468.html "FBgn0039745, FBan0007950" protein_coding_gene "Dromel_CG7950_FBtr0085563_CHCHD4inmorf_mORF, CG7950" IPR010625=CHCH CG7950 16-Dec-15 2015_12 DRSC28664 IK 2.175635786 0.510433806 0.616536938 -0.532649585 2.144138521 0.143507261 FBgn0010854 l(3)05057 lethal (3) 05057 http://flybase.net/reports/FBgn0010854.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0065494 l(2)SH1225 lethal (2) SH1225 http://flybase.net/reports/FBgn0065494.html gene l(2)SH2 1225 16-Dec-15 2015_12 "lethal,recessive" FBgn0069117 mus213 mutagen-sensitive 213 http://flybase.net/reports/FBgn0069117.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0066073 Su(var)2-13 Su(var)2-13 http://flybase.net/reports/FBgn0066073.html gene 16-Dec-15 2015_12 FBgn0264355 4A1 http://flybase.net/reports/FBgn0264355.html gene 16-Dec-15 2015_12 "visible,somatic clone" "eye,somatic clone" FBgn0002530 Lap-D Leucine aminopeptidase D http://flybase.net/reports/FBgn0002530.html "FBgn0013289, FBgn0013290" gene 0004177=aminopeptidase activity 0005829=cytosol "LapD, LAP-D, leucine aminopeptidase, Lap, LAP, leucyl aminopeptidase, Leucine aminopeptidase P" 16-Dec-15 2015_12 electrophoretic variant FBgn0036771 CG14353 http://flybase.net/reports/FBgn0036771.html protein_coding_gene "IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG14353 16-Dec-15 2015_12 ENSDARG00000037334(wdr92) ENSXETG00000017344(WDR92) ENSMUSG00000078970(Wdr92) ENSG00000221823(PPP3R1) viable FBgn0026787 Nhe1 Na+/H+ hydrogen exchanger 1 http://flybase.net/reports/FBgn0026787.html protein_coding_gene 0015385=sodium:proton antiporter activity "0006885=regulation of pH, 0055085=transmembrane transport, 0006814=sodium ion transport" 0016021=integral component of membrane "DmNHE1, CG12178, NHE1, nhe1, Nhe1" "IPR004709=Na+/H+ exchanger, IPR018409=Na+/H+ exchanger, isoform 8, IPR006153=Cation/H+ exchanger, IPR018422=Cation/H+ exchanger, CPA1 family" CG12178 16-Dec-15 2015_12 ENSDARG00000020699(slc9a8) YDR456W(NHX1) WBGene00003735(nhx-8) ENSXETG00000024003(SLC9A8) ENSMUSG00000039463(Slc9a8) ENSG00000197818(SLC9A8) viable FBgn0010373 sib sibless http://flybase.net/reports/FBgn0010373.html gene 16-Dec-15 2015_12 FBgn0259718 CG42372 http://flybase.net/reports/FBgn0259718.html protein_coding_gene Dromel_CG30100_FBtr0087140_uORF IPR008011=Complex 1 LYR protein CG42372 16-Dec-15 2015_12 FBgn0010936 l(3)09656 lethal (3) 09656 http://flybase.net/reports/FBgn0010936.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0061135 l(3)S001620b lethal (3) S001620b http://flybase.net/reports/FBgn0061135.html gene 0016/20 16-Dec-15 2015_12 lethal FBgn0065460 l(2)SH1380 lethal (2) SH1380 http://flybase.net/reports/FBgn0065460.html gene l(2)SH2 1380 16-Dec-15 2015_12 "lethal,recessive" FBgn0267381 T:CycB.1-266 CycB degron sequence http://flybase.net/reports/FBgn0267381.html engineered_tag 16-Dec-15 2015_12 FBgn0060909 l(3)S043005a lethal (3) S043005a http://flybase.net/reports/FBgn0060909.html gene 0430/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0243486 rdo reduced ocelli http://flybase.net/reports/FBgn0243486.html "FBgn0003220, FBgn0032661" protein_coding_gene 0008056=ocellus development "Reduced ocelli, CG15151, PFE, CT35050, Pray For Elves, Rdo" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG15151 16-Dec-15 2015_12 WBGene00011345(T01G9.3) ENSXETG00000015538(IGFALS) FBgn0060403 l(3)S131103 lethal (3) S131103 http://flybase.net/reports/FBgn0060403.html gene 1311/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031824 CG9547 http://flybase.net/reports/FBgn0031824.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0004361=glutaryl-CoA dehydrogenase activity" "0055114=oxidation-reduction process, 0006568=tryptophan metabolic process, 0046948=hydroxylysine catabolic process, 0006554=lysine catabolic process" "0005759=mitochondrial matrix, 0005875=microtubule associated complex" 152078_at "IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal" CG9547 16-Dec-15 2015_12 "ENSDARG00000037057(gcdh),ENSDARG00000038361" WBGene00010052(F54D5.7) ENSXETG00000007932(gcdh) ENSMUSG00000003809(Gcdh) ENSG00000105607(GCDH) DRSC03260 K -0.49002739 -0.396702213 0.227175872 0.211034442 2.069404073 0.002644414 FBgn0014068 Su(tor)3-344 Su(tor)3-344 http://flybase.net/reports/FBgn0014068.html gene 16-Dec-15 2015_12 FBgn0014885 Su(phl)4 Suppressor of pole hole 4 http://flybase.net/reports/FBgn0014885.html gene "Su(D-raf)4, Suppressor of raf-like-oncogene" 16-Dec-15 2015_12 FBgn0026218 l(3)06265 lethal (3) 06265 http://flybase.net/reports/FBgn0026218.html gene 16-Dec-15 2015_12 lethal FBgn0029801 CG15771 http://flybase.net/reports/FBgn0029801.html FBgn0053074 protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process "28571108, CR33074" "IPR023214=HAD-like domain, IPR011950=HAD-superfamily hydrolase, subfamily IA, CTE7, IPR006439=HAD hydrolase, subfamily IA" CG15771 16-Dec-15 2015_12 "ENSDARG00000068619,ENSDARG00000068935" "WBGene00008610(F09C3.2),WBGene00018464" ENSXETG00000024902(hdhd4) "ENSMUSG00000043346,ENSMUSG00000053916(Nanp)" ENSG00000170191(NANP) viable embryonic/larval hemocyte | third instar larval stage FBgn0041153 freshair freshair http://flybase.net/reports/FBgn0041153.html gene 16-Dec-15 2015_12 FBgn0082922 snoRNA:Or-aca4 snoRNA:Or-aca4 http://flybase.net/reports/FBgn0082922.html snoRNA_gene "Or-aca4, CR34543, DmOr_aca4, DmOr_aca4 snoRNA, Oaca-4, chr2R:13131609..13131698" CR34543 16-Dec-15 2015_12 FBgn0030048 CG12112 http://flybase.net/reports/FBgn0030048.html protein_coding_gene CG12112 16-Dec-15 2015_12 "viable,fertile" FBgn0014213 l(2)31Ba lethal (2) 31Ba http://flybase.net/reports/FBgn0014213.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085192 CG34163 http://flybase.net/reports/FBgn0085192.html protein_coding_gene CG34163 16-Dec-15 2015_12 FBgn0002282 l(3)73Ag lethal (3) 73Ag http://flybase.net/reports/FBgn0002282.html gene l(3)133.59 16-Dec-15 2015_12 lethal "adult abdomen,tergite" FBgn0002288 l(3)73Ca lethal (3) 73Ca http://flybase.net/reports/FBgn0002288.html gene 16-Dec-15 2015_12 lethal FBgn0031596 CG15429 http://flybase.net/reports/FBgn0031596.html FBgn0063308 protein_coding_gene 0046331=lateral inhibition BcDNA:AT23465 IPR001199=Cytochrome b5-like heme/steroid binding domain CG15429 16-Dec-15 2015_12 ENSDARG00000056007(cyb5d1) "ENSMUSG00000032889(Gm6685),ENSMUSG00000044795(Cyb5d1)" ENSG00000182224(CYB5D1) "viable,visible" chaeta FBgn0028564 slug slug http://flybase.net/reports/FBgn0028564.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" larva FBgn0019749 l(1)815-5 lethal (1) 815-5 http://flybase.net/reports/FBgn0019749.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015356 anon-99Ce anon-99Ce http://flybase.net/reports/FBgn0015356.html gene 16-Dec-15 2015_12 FBgn0019908 air aircraft http://flybase.net/reports/FBgn0019908.html gene 16-Dec-15 2015_12 "viable,fertile,flightless" wing FBgn0069956 CG41063 http://flybase.net/reports/FBgn0069956.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032299 CG17127 http://flybase.net/reports/FBgn0032299.html protein_coding_gene CG17127 16-Dec-15 2015_12 FBgn0034301 CG5756 http://flybase.net/reports/FBgn0034301.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG5756 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0266914 CR45374 http://flybase.net/reports/FBgn0266914.html non_protein_coding_gene CR45374 16-Dec-15 2015_12 FBgn0014331 l(3)ry87 lethal (3) ry87 http://flybase.net/reports/FBgn0014331.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034272 Ir54a Ionotropic receptor 54a http://flybase.net/reports/FBgn0034272.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 54a, DmelIR54a, CG14487, IR54a" CG14487 16-Dec-15 2015_12 viable DRSC06459 K 0.152835364 -0.162004685 0.301238081 0.461127447 1.500600904 0.769335715 FBgn0010636 l(2)07129 lethal (2) 07129 http://flybase.net/reports/FBgn0010636.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0037454 CG1137 http://flybase.net/reports/FBgn0037454.html FBgn0061571 protein_coding_gene 0008233=peptidase activity anon-WO0118547.86 "IPR000048=IQ motif, EF-hand binding site" CG1137 16-Dec-15 2015_12 ENSDARG00000035551(si:dkey-125i10.6) viable FBgn0260617 2L1748 http://flybase.net/reports/FBgn0260617.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0000971 Fs(2)Him Female sterile (2) Himca http://flybase.net/reports/FBgn0000971.html gene "Fs(2)Sz5, Himca" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant" egg FBgn0044056 Gpal Gpal http://flybase.net/reports/FBgn0044056.html gene 0003677=DNA binding 0005634=nucleus GPAL 16-Dec-15 2015_12 FBgn0015034 Cyp4e1 Cytochrome P450-4e1 http://flybase.net/reports/FBgn0015034.html FBgn0033293 protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "P450, CG2062, 4e1, CYP4E1, P-450" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG2062 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0004590 Eig71Ec Ecdysone-induced gene 71Ec http://flybase.net/reports/FBgn0004590.html protein_coding_gene "0007552=metamorphosis, 0042742=defense response to bacterium" 0005576=extracellular region "gene-III, L71, L71-3, CG7608, LP11175p, 71E-Gene-III, Gene III, gene III, Eig 71Ec, III" IPR003475=Insect protein of unknown function CG7608 16-Dec-15 2015_12 viable FBgn0065796 l(2)SH0416 lethal (2) SH0416 http://flybase.net/reports/FBgn0065796.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029690 CG6414 http://flybase.net/reports/FBgn0029690.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR019826=Carboxylesterase type B, active site, IPR002018=Carboxylesterase, type B" CG6414 16-Dec-15 2015_12 WBGene00019652(K11G9.1) viable FBgn0065696 l(2)SH0636 lethal (2) SH0636 http://flybase.net/reports/FBgn0065696.html gene l(2)SH2 0636 16-Dec-15 2015_12 "lethal,recessive" FBgn0001401 l(1)2Fd lethal (1) 2Fd http://flybase.net/reports/FBgn0001401.html gene "l(1)EC226, l(1)N11, N11, N6, l26, D82, l(1)N8, EC226" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0265797 CR44586 http://flybase.net/reports/FBgn0265797.html non_protein_coding_gene CR44586 16-Dec-15 2015_12 FBgn0260086 2L3910 http://flybase.net/reports/FBgn0260086.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0261004 asl asterless http://flybase.net/reports/FBgn0261004.html "FBgn0259895, FBgn0004916, FBgn0004830, FBgn0037348, FBgn0043878" protein_coding_gene "0050954=sensory perception of mechanical stimulus, 0007099=centriole replication, 0051297=centrosome organization, 0007098=centrosome cycle, 0035058=nonmotile primary cilium assembly, 0007288=sperm axoneme assembly, 0008356=asymmetric cell division, 0007338=single fertilization" "0005813=centrosome, 0000242=pericentriolar material, 0036064=ciliary basal body, 0005814=centriole" "CG2919, sdu, ASL, mecD, mechanosensory mutant D, star dust, mechanosensory D, Asterless, Asl" CG2919 16-Dec-15 2015_12 FBgn0026156 wlf wolf http://flybase.net/reports/FBgn0026156.html gene 0045792=negative regulation of cell size 16-Dec-15 2015_12 FBgn0022399 Gase3 Gastric serine protease 3 http://flybase.net/reports/FBgn0022399.html gene 0008236=serine-type peptidase activity 16-Dec-15 2015_12 FBgn0067634 233y-a 233y-a http://flybase.net/reports/FBgn0067634.html gene 233y 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0264261 CR43761 http://flybase.net/reports/FBgn0264261.html non_protein_coding_gene lincRNA.155 CR43761 16-Dec-15 2015_12 FBgn0263892 l(3)GL45 http://flybase.net/reports/FBgn0263892.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0061140 l(3)S000625b lethal (3) S000625b http://flybase.net/reports/FBgn0061140.html gene 25-Jun 16-Dec-15 2015_12 lethal FBgn0262376 mir-219 mir-219 stem loop http://flybase.net/reports/FBgn0262376.html "FBgn0067723, FBgn0262190" miRNA_gene "miR-219, mir-219, CR33579, CR42897, dme-mir-219" CR42897 16-Dec-15 2015_12 "lethal,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "eye,wing,1st posterior cell" FBgn0034563 CG15649 http://flybase.net/reports/FBgn0034563.html FBgn0047316 protein_coding_gene BcDNA:GH08880 CG15649 16-Dec-15 2015_12 "viable,visible,body color defective,planar polarity defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0036134 FoxK Forkhead box K http://flybase.net/reports/FBgn0036134.html protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003690=double-stranded DNA binding, 0008134=transcription factor binding, 0000287=magnesium ion binding, 0043565=sequence-specific DNA binding, 0008301=DNA binding, bending, 0003700=sequence-specific DNA binding transcription factor activity" "0007389=pattern specification process, 0010628=positive regulation of gene expression, 0009888=tissue development, 0007494=midgut development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0051607=defense response to virus, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0007495=visceral mesoderm-endoderm interaction involved in midgut development, 0098586=cellular response to virus" "0005667=transcription factor complex, 0005634=nucleus" "fork head transcription factor short isoform, FoxK, Mnf, MNF, DmMNF, dFoxK, fd68A, DmLD16137, forkhead domain 68A, CG11799, fork head transcription factor long isoform, fork head box K, myocyte nuclear factor" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000253=Forkhead-associated (FHA) domain, IPR001766=Fork head domain, IPR018122=Fork head domain conserved site1, IPR008984=SMAD/FHA domain" CG11799 16-Dec-15 2015_12 "ENSDARG00000037872(foxk1),ENSDARG00000011609(si:ch211-262e15.1),ENSDARG00000030583" "YNL068C(FKH2),YIL131C(FKH1)" WBGene00004013(pha-4) ENSXETG00000022803(FOXK2) "ENSMUSG00000056493,ENSMUSG00000039275(Foxk2)" "ENSG00000164916(FOXK1),ENSG00000141568(FOXK2)" viable FBgn0033683 CG18343 http://flybase.net/reports/FBgn0033683.html protein_coding_gene CG18343 16-Dec-15 2015_12 viable FBgn0051619 nolo no long nerve cord http://flybase.net/reports/FBgn0051619.html "FBgn0032958, FBgn0032959, FBgn0040517" protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" 0006508=proteolysis 0005578=proteinaceous extracellular matrix "CG13236, CG31619, CT6940, CG2122, CG2131" "IPR013783=Immunoglobulin-like fold, IPR013273=Peptidase M12B, ADAM-TS, IPR003598=Immunoglobulin subtype 2, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR010909=PLAC, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain" CG31619 16-Dec-15 2015_12 WBGene00009958(F53B6.2) "ENSG00000178031(ADAMTSL1),ENSG00000156218(ADAMTSL3)" "visible,partially lethal - majority die,some die during pupal stage,lethal" mesothoracic tergum FBgn0267309 CR45745 http://flybase.net/reports/FBgn0267309.html non_protein_coding_gene CR45745 16-Dec-15 2015_12 FBgn0033997 Ir51a Ionotropic receptor 51a http://flybase.net/reports/FBgn0033997.html pseudogene_attribute "IR51a, CG12953, CR12953, ionotropic receptor 51a, DmelIR51a" CR12953 16-Dec-15 2015_12 FBgn0035318 CG9018 http://flybase.net/reports/FBgn0035318.html protein_coding_gene FBgn0035318 "IPR008942=ENTH/VHS, IPR006903=RNA polymerase II-binding domain, IPR006569=CID domain" CG9018 16-Dec-15 2015_12 "ENSDARG00000038113(rprd1b),ENSDARG00000060755(LOC560565)" WBGene00015347(cids-1) "ENSXETG00000017322(BC074536.1),ENSXETG00000021931(RPRD1A)" "ENSMUSG00000027651(Rprd1b),ENSMUSG00000040446(Rprd1a)" "ENSG00000101413(RPRD1B),ENSG00000141425(RPRD1A)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0039015 Takl2 Tak1-like 2 http://flybase.net/reports/FBgn0039015.html protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation 0005737=cytoplasm "CG4803, TAK" "IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG4803 16-Dec-15 2015_12 "viable,fertile" DRSC15650 K -0.317109345 0.089296187 -0.159757247 -0.068964564 0.459173196 -1.558132663 FBgn0027985 l(3)S132703 lethal (3) S132703 http://flybase.net/reports/FBgn0027985.html gene 1327/03 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0004778 Ccp84Af Ccp84Af http://flybase.net/reports/FBgn0004778.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" "0022008=neurogenesis, 0040003=chitin-based cuticle development" 0031012=extracellular matrix "cuticle cluster 3, CG1331, unnamed, DmelCcp84Af, BG:DS00004.6, Ccp, cc3" IPR000618=Insect cuticle protein CG1331 16-Dec-15 2015_12 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC12591 I -0.79306758 -1.600176981 -1.23938521 0.336325075 0.1576713 0.231526345 FBgn0044125 E(rst)B37 E(rst)B37 http://flybase.net/reports/FBgn0044125.html gene 0001745=compound eye morphogenesis B37 16-Dec-15 2015_12 viable FBgn0014988 l(2)46Dd lethal (2) 46Dd http://flybase.net/reports/FBgn0014988.html gene "X, Group X" 16-Dec-15 2015_12 lethal FBgn0260243 E(var)3-9 Enhancer of variegation 3-9 http://flybase.net/reports/FBgn0260243.html "FBgn0013255, FBgn0022347" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0070827=chromatin maintenance 0005634=nucleus "anon-fast-evolving-1E9, 1E9, anon-EST:fe1E9, E(var)3-9, Anon1E9, unnamed, anon1E9, CG11971, E-var(3)9" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG11971 16-Dec-15 2015_12 FBgn0267011 CR45455 http://flybase.net/reports/FBgn0267011.html non_protein_coding_gene CR45455 16-Dec-15 2015_12 FBgn0265658 CR44465 http://flybase.net/reports/FBgn0265658.html non_protein_coding_gene CR44465 16-Dec-15 2015_12 FBgn0030745 CG4239 http://flybase.net/reports/FBgn0030745.html protein_coding_gene 0005261=cation channel activity 0015672=monovalent inorganic cation transport 0016020=membrane IPR007866=TRIC channel CG4239 16-Dec-15 2015_12 ENSDARG00000024047(tmem38a) "WBGene00013268(Y57A10A.28),WBGene00013255(Y57A10A.10)" "ENSXETG00000000907(tmem38b),ENSXETG00000021455(tmem38a)" "ENSMUSG00000031791(Tmem38a),ENSMUSG00000028420(Tmem38b)" "ENSG00000072954(TMEM38A),ENSG00000095209(TMEM38B)" "lethal,partially lethal - majority die" FBgn0024723 Su(var)47E48A Su(var)47E48A http://flybase.net/reports/FBgn0024723.html gene unnamed 16-Dec-15 2015_12 FBgn0250911 CG42245 http://flybase.net/reports/FBgn0250911.html protein_coding_gene IPR027911=Domain of unknown function DUF4604 CG42245 16-Dec-15 2015_12 ENSDARG00000029615(zgc:77056) WBGene00012029(T25G3.1) ENSXETG00000008498(KIAA1143) ENSMUSG00000032551(1110059G10Rik) ENSG00000163807(KIAA1143) FBgn0005242 l(3)R102 lethal of Roberts 102 http://flybase.net/reports/FBgn0005242.html gene l(3)102 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0083040 snoRNA:ë¬18S-1854c snoRNA:ë¬18S-1854c http://flybase.net/reports/FBgn0083040.html snoRNA_gene "Psi18S-1854c, psi18S-1854c, chrX:16979184..16979324, CR34598" CR34598 16-Dec-15 2015_12 FBgn0259326 EP-319 http://flybase.net/reports/FBgn0259326.html gene 16-Dec-15 2015_12 visible "wing hair,wing margin,chaeta" FBgn0260806 EP3-934 http://flybase.net/reports/FBgn0260806.html gene 16-Dec-15 2015_12 FBgn0010094 Su(wa4) Suppressor of white-apricot 4 http://flybase.net/reports/FBgn0010094.html gene 16-Dec-15 2015_12 FBgn0262838 CG43202 http://flybase.net/reports/FBgn0262838.html protein_coding_gene "CG42737, DMG8-chr2R.26.014, chr2R.1731" CG43202 16-Dec-15 2015_12 FBgn0011183 l(1)294-22 lethal (1) 294-22 http://flybase.net/reports/FBgn0011183.html FBgn0010200 gene 294-22 16-Dec-15 2015_12 "lethal,recessive" FBgn0032090 CG9582 http://flybase.net/reports/FBgn0032090.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG9582 16-Dec-15 2015_12 "YOR222W(ODC2),YPL134C(ODC1)" "viable,fertile" FBgn0051699 CG31699 http://flybase.net/reports/FBgn0051699.html protein_coding_gene 16-Dec-15 2015_12 DRSC22062 E -0.490699578 0.050299163 -1.833773621 -0.143108806 0.696804445 -0.211590067 FBgn0017627 Eig45Aa Eig45Aa http://flybase.net/reports/FBgn0017627.html gene "Ecdysone-induced gene 45A, Eig45-1" 16-Dec-15 2015_12 FBgn0021768 nudC nudC http://flybase.net/reports/FBgn0021768.html FBgn0036664 protein_coding_gene "0048477=oogenesis, 0007097=nuclear migration" "0005737=cytoplasm, 0005829=cytosol, 0005875=microtubule associated complex" "NUDC, CG9710, Q9VVA6, DnudC, NudC" "IPR007052=CS domain, IPR025934=NudC N-terminal domain, IPR008978=HSP20-like chaperone" CG9710 16-Dec-15 2015_12 ENSDARG00000008052(nudc) WBGene00003829(nud-1) ENSXETG00000020686(NUDC) ENSMUSG00000028851(Nudc) ENSG00000090273(NUDC) "viable,fertile" FBgn0002448 l(3)SG1 lethal (3) SG1 http://flybase.net/reports/FBgn0002448.html FBgn0004706 gene "l(3)A4, l(3)dsl4, l(3)dsl-4, l(3)g60L" 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0035526 CG1316 http://flybase.net/reports/FBgn0035526.html protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" cg1316 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG1316 16-Dec-15 2015_12 ENSDARG00000063731(rbm45) ENSXETG00000015007(RBM45) ENSMUSG00000042369(Rbm45) ENSG00000155636(RBM45) "partially lethal - majority die,some die during pupal stage" FBgn0015569 ë±-Est10 ë±-Esterase-10 http://flybase.net/reports/FBgn0015569.html FBgn0046454 protein_coding_gene 0052689=carboxylic ester hydrolase activity 0007476=imaginal disc-derived wing morphogenesis "CG1131, aE10, Esterase-10, fragment K, alphaE10, K, unnamed, alpha-Ests, DmalphaE10, alpha-Est10, anon-WO0172774.144" "IPR019826=Carboxylesterase type B, active site, IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG1131 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" viable FBgn0004435 Gë±q G protein ë± q subunit http://flybase.net/reports/FBgn0004435.html FBgn0004178 protein_coding_gene "0005525=GTP binding, 0004871=signal transducer activity, 0003924=GTPase activity, 0001664=G-protein coupled receptor binding, 0031683=G-protein beta/gamma-subunit complex binding" "0007202=activation of phospholipase C activity, 0016199=axon midline choice point recognition, 0016060=metarhodopsin inactivation, 0043052=thermotaxis, 0007186=G-protein coupled receptor signaling pathway, 0007608=sensory perception of smell, 0007602=phototransduction, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0002385=mucosal immune response, 0030322=stabilization of membrane potential, 0007629=flight behavior, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway, 0016056=rhodopsin mediated signaling pathway, 0060158=phospholipase C-activating dopamine receptor signaling pathway, 0006897=endocytosis, 0071244=cellular response to carbon dioxide" "0016027=inaD signaling complex, 0005834=heterotrimeric G-protein complex, 0016028=rhabdomere, 0005886=plasma membrane, 0031234=extrinsic component of cytoplasmic side of plasma membrane" "Gq/11, Galpha49B, Dgq, G[q], dGqalpha-3, DGalphaq, DGqalpha, dgq, G?q, Galphaq, Galpha[[q]], Gqalpha[[e]], dGq, G[[alphaq]], CG17759, dGaalpha, dG[[q]]alpha, Gqa-3, G[[q]]alpha, G-protein alpha49B, G[[qalpha]], dGqalpha-49b, Gq, Gqalpha, sast, DmGalpha[[q]], DGalpha[[q]], DGq, small amplify and slow termination, G protein 49B, galpha49B, G protein alpha49B, G alpha 49B, dG[[alphaq]], Galpha49b, dGqalpha, Gaq, G[[a]]q, dGqa-49b, Dromel_CG17759_galpha49b_mORF, Galpha, Gqalpha{e}, G-protein-alpha[[q]], G-protein alpha subunit, Gqalphae, G[[q]], dgqalpha" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000654=G-protein alpha subunit, group Q, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025=G protein alpha subunit, helical insertion" CG17759 16-Dec-15 2015_12 ENSDARG00000011487(gnaq) WBGene00001196(egl-30) "ENSXETG00000014367(gna11),ENSXETG00000003621(gnaq)" "ENSMUSG00000024639(Gnaq),ENSMUSG00000034781(Gna11)" "ENSG00000156052(GNAQ),ENSG00000088256(GNA11)" " adult stage , spermatogenesis && adult stage " " ocellus

, retina

, testis

, adult brain

, eye

, adult head

" adult stage " proboscis | restricted

, eye

, ocellus

, medulla

, rhabdomere

, lamina

, maxillary palpus

, antennal segment 3

, photoreceptor cell

" "lethal - all die before end of first instar larval stage,some die during first instar larval stage,neurophysiology defective,visual behavior defective,recessive,behavior defective,immune response defective,thermotaxis behavior defective,viable,chemosensitive behavior defective,flightless,partially,smell perception defective,heat sensitive,sensory perception defective,somatic clone,dominant,lethal - all die before end of larval stage,some die during larval stage,lethal,wild-type,neuroanatomy defective" "photoreceptor cell,rhabdomere,photoreceptor,eye photoreceptor cell,retina,conditional,adult olfactory receptor neuron ab11a,wing,adult olfactory receptor neuron Or59b,adult olfactory receptor neuron Gr21a/63a,somatic clone,fascicle | embryonic stage,pCC neuron,commissure | embryonic stage,neuropil | embryonic stage,adult olfactory receptor neuron Or42b,adult olfactory receptor neuron Or22,heat sensitive,dMP2 neuron" DRSC07432 E 0.661768117 0.294638196 1.880932623 0.870461472 0.450598843 0.343098473 FBgn0264569 CR43941 http://flybase.net/reports/FBgn0264569.html non_protein_coding_gene CR43941 16-Dec-15 2015_12 FBgn0034819 CG9877 http://flybase.net/reports/FBgn0034819.html FBgn0047141 protein_coding_gene BcDNA:RE26296 CG9877 16-Dec-15 2015_12 DRSC04587 I 1.537782134 -0.365227241 0.224643899 1.419732769 -0.51172772 -0.238694484 FBgn0022010 l(2)k09202 lethal (2) k09202 http://flybase.net/reports/FBgn0022010.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266886 CR45347 http://flybase.net/reports/FBgn0266886.html non_protein_coding_gene CR45347 16-Dec-15 2015_12 FBgn0086556 MRE25 mRNA-like ncRNA in embryogenesis 25 http://flybase.net/reports/FBgn0086556.html non_protein_coding_gene RH66770 16-Dec-15 2015_12 FBgn0040389 mRpL14 mitochondrial ribosomal protein L14 http://flybase.net/reports/FBgn0040389.html "FBgn0029613, FBgn0061383" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "L14, EG:BACH48C10.6, mRPL14, BcDNA:RH18819, CG14048" "IPR000218=Ribosomal protein L14b/L23e, IPR023571=Ribosomal protein L14 domain" CG14048 16-Dec-15 2015_12 "ENSDARG00000068886(mrpl14),ENSDARG00000068867" ENSMUSG00000023939(Mrpl14) ENSG00000180992(MRPL14) "viable,visible" trichogen cell FBgn0261505 CR42653 http://flybase.net/reports/FBgn0261505.html pseudogene_attribute noncoding_9454 CR42653 16-Dec-15 2015_12 FBgn0051798 CG31798 http://flybase.net/reports/FBgn0051798.html FBgn0044689 protein_coding_gene anon-WO0140519.187 IPR011990=Tetratricopeptide-like helical domain CG31798 16-Dec-15 2015_12 viable FBgn0267574 CR45914 http://flybase.net/reports/FBgn0267574.html non_protein_coding_gene CR45914 16-Dec-15 2015_12 FBgn0052399 CG32399 http://flybase.net/reports/FBgn0052399.html FBgn0064820 protein_coding_gene BcDNA:RH33996 16-Dec-15 2015_12 FBgn0001655 l(1)ds9 lethal (1) discs small 9 http://flybase.net/reports/FBgn0001655.html gene "l(1)d.sml.-9, l(1)d sml-9" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0029144 P(3)79D P(3)79D http://flybase.net/reports/FBgn0029144.html gene 16-Dec-15 2015_12 FBgn0261993 CG42811 http://flybase.net/reports/FBgn0261993.html "FBan0018669, FBgn0040599" protein_coding_gene CG18669 IPR006631=Protein of unknown function DM4/12 CG42811 16-Dec-15 2015_12 FBgn0015486 l(2)46Cj lethal (2) 46Cj http://flybase.net/reports/FBgn0015486.html FBgn0019713 gene "20.10, l(2)46CFo, Complementation group O, unnamed, O" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval digestive system,presumptive embryonic/larval tracheal system" FBgn0053737 snmRNA:430:CR33737 snmRNA:430:CR33737 http://flybase.net/reports/FBgn0053737.html non_protein_coding_gene CR33737 CR33737 16-Dec-15 2015_12 FBgn0030292 CG11752 http://flybase.net/reports/FBgn0030292.html "FBgn0027728, FBgn0047013" protein_coding_gene 0005747=mitochondrial respiratory chain complex I "anon-EST:Posey214, BcDNA:RH44935" IPR026193=NADH-ubiquinone oxidoreductase flavoprotein 3 CG11752 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0019702 l(2)42Bc lethal (2) 42Bc http://flybase.net/reports/FBgn0019702.html gene "l(2)5CC1, 5CC1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0005403 l(1)10Bo lethal (1) 10Bo http://flybase.net/reports/FBgn0005403.html gene l(1)VE328 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone" FBgn0265600 kay::Dpse\kay http://flybase.net/reports/FBgn0265600.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0041603 fsco four score http://flybase.net/reports/FBgn0041603.html gene "0007110=meiosis I cytokinesis, 0000916=actomyosin contractile ring contraction, 0043147=meiotic spindle stabilization, 0007111=meiosis II cytokinesis" 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male,spermatid & nucleus | supernumeraryp25),spindle & meiotic telophase I | malep25),contractile ring & meiotic telophase I | malep25),spindle & meiotic telophase II | malep25),contractile ring & meiotic telophase II | malep25)" FBgn0011454 l(3)neo10 lethal (3) neo10 http://flybase.net/reports/FBgn0011454.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060870 l(3)S047117 lethal (3) S047117 http://flybase.net/reports/FBgn0060870.html gene 0471/17 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0015546 spel1 spellchecker1 http://flybase.net/reports/FBgn0015546.html protein_coding_gene "0000404=heteroduplex DNA loop binding, 0003684=damaged DNA binding, 0008094=DNA-dependent ATPase activity, 0000406=double-strand/single-strand DNA junction binding, 0032138=single base insertion or deletion binding, 0032137=guanine/thymine mispair binding, 0000403=Y-form DNA binding, 0005524=ATP binding, 0000400=four-way junction DNA binding" "0006298=mismatch repair, 0006311=meiotic gene conversion, 0036297=interstrand cross-link repair, 0045128=negative regulation of reciprocal meiotic recombination, 0042771=intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, 0031573=intra-S DNA damage checkpoint, 0010224=response to UV-B, 0000710=meiotic mismatch repair, 0006301=postreplication repair, 0010165=response to X-ray, 0043570=maintenance of DNA repeat elements, 0006302=double-strand break repair" "0032301=MutSalpha complex, 0032302=MutSbeta complex, 0000228=nuclear chromosome" "spellchecker, Msh2, spel-1, BG:DS01068.9, SPEL1, spel, CG4215, spellchecker 1" "IPR007861=DNA mismatch repair protein MutS, clamp, IPR007696=DNA mismatch repair protein MutS, core, IPR007695=DNA mismatch repair protein MutS-like, N-terminal, IPR007860=DNA mismatch repair protein MutS, connector domain, IPR000432=DNA mismatch repair protein MutS, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011184=DNA mismatch repair MutS" CG4215 16-Dec-15 2015_12 ENSDARG00000018022(msh2) YOL090W(MSH2) WBGene00003418(msh-2) ENSXETG00000022615(MSH2) ENSMUSG00000024151(Msh2) ENSG00000095002(MSH2) viable DRSC03617 E 1.183911735 -0.362520525 -1.831481868 0.367864972 -0.135616213 -0.117266577 FBgn0013258 E(var)35 E(var)35 http://flybase.net/reports/FBgn0013258.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0020877 anon-A8 anon-A8 http://flybase.net/reports/FBgn0020877.html gene 2-A8 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0020832 l(2)PW "Pullman, Washington" http://flybase.net/reports/FBgn0020832.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014329 l(3)ry74 lethal (3) ry74 http://flybase.net/reports/FBgn0014329.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015024 CkIë± Casein kinase Ië± http://flybase.net/reports/FBgn0015024.html "FBgn0029043, FBgn0066807, FBgn0066808" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005515=protein binding, 0005524=ATP binding" "0006909=phagocytosis, 0045732=positive regulation of protein catabolic process, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0030111=regulation of Wnt signaling pathway, 0006468=protein phosphorylation, 0007224=smoothened signaling pathway, 0016055=Wnt signaling pathway, 0030162=regulation of proteolysis, 0030163=protein catabolic process, 0006281=DNA repair, 0022008=neurogenesis, 0002121=inter-male aggressive behavior, 0045879=negative regulation of smoothened signaling pathway, 0000902=cell morphogenesis" "0005737=cytoplasm, 0005634=nucleus" "CkI alpha, dmckI, CKI alpha, casein kinase I, Casein kinase I, PKA-C, CK1, CkIa, Casein Kinase 1alpha, ck1alpha, ck1a, CK I, CK1a, Casein kinase Ialpha, CkIalpha, CK1alpha, anon-WO03040301.93, casein kinase Ialpha, CKIalpha, CG2028, l(1)G0492, Ck1alpha, Casein Kinase 1, CKIa, dmCK1, casein kinase-1, Casein kinase 1, CKI, casein kinase 1, anon-WO03040301.95, casein kinase 1a, caesin kinase I alpha" "IPR017441=Protein kinase, ATP binding site, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG2028 16-Dec-15 2015_12 "ENSDARG00000052674(csnk1a1),ENSDARG00000007993(LOC567617)" WBGene00002202(kin-19) ENSXETG00000020861(csnk1a1) ENSMUSG00000024576(Csnk1a1) "ENSG00000113712(CSNK1A1),ENSG00000180138(CSNK1A1L)" "visible,somatic clone,lethal,behavior defective,recessive,female sterile,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,eye disc,wing,embryonic/first instar larval cuticle,ventral nerve cord commissure,longitudinal connective,embryonic epidermis,wing margin bristle,ectopic,embryonic/larval neuroblast,ganglion mother cell,synapse,neuromuscular junction" DRSC22609 K 0.226418346 0.061498999 -0.219256744 1.367663992 1.505405909 1.157408614 FBgn0005717 l(1)TK123 lethal (1) TK123 http://flybase.net/reports/FBgn0005717.html gene l123 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004577 Pxd Peroxidase http://flybase.net/reports/FBgn0004577.html protein_coding_gene "0005506=iron ion binding, 0004601=peroxidase activity, 0020037=heme binding" "0022008=neurogenesis, 0045471=response to ethanol, 0006979=response to oxidative stress, 0006909=phagocytosis, 0055114=oxidation-reduction process, 0007306=eggshell chorion assembly" "0005576=extracellular region, 0042600=chorion" "PO, DmPO, peroxidase, unnamed, CG3477, Dpxd" "IPR019791=Haem peroxidase, animal, IPR010255=Haem peroxidase, IPR029585=Peroxidase, insect" CG3477 16-Dec-15 2015_12 "WBGene00022743(mlt-7),WBGene00017968(F32A5.2)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0002313 l(3)85Ad lethal (3) 85Ad http://flybase.net/reports/FBgn0002313.html gene L4 16-Dec-15 2015_12 lethal FBgn0037182 ArfGAP3 ADP-ribosylation factor GTPase activating protein 3 http://flybase.net/reports/FBgn0037182.html protein_coding_gene 0005096=GTPase activator activity "0001745=compound eye morphogenesis, 0043087=regulation of GTPase activity, 0046331=lateral inhibition" "0005737=cytoplasm, 0005912=adherens junction" "dArfGAP3, arfgap1, CG6838" IPR001164=Arf GTPase activating protein CG6838 16-Dec-15 2015_12 ENSDARG00000067601(arfgap2) YER122C(GLO3) WBGene00017217(F07F6.4) ENSXETG00000005097(znf289) "ENSMUSG00000027255(Arfgap2),ENSMUSG00000054277(Arfgap3)" "ENSG00000100262,ENSG00000149182(ARFGAP2)" "viable,visible" "chaeta,ommatidium,retina" FBgn0250754 CG42232 http://flybase.net/reports/FBgn0250754.html "FBan0014896, FBgn0026006, FBgn0038433, FBgn0038434" protein_coding_gene "CG14897, CG14896, clone 1.14, anon-EST:Liang-1.14" "IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG42232 16-Dec-15 2015_12 FBgn0046654 anon-38D.10 anon-38D.10 http://flybase.net/reports/FBgn0046654.html gene 38D.10 16-Dec-15 2015_12 FBgn0000031 AcpGI Accessory gland protein G-I http://flybase.net/reports/FBgn0000031.html gene "grey-1, AcpG, Acp-g1" 16-Dec-15 2015_12 electrophoretic variant FBgn0005675 Dia2 Diaphorase 2 http://flybase.net/reports/FBgn0005675.html gene 0004148=dihydrolipoyl dehydrogenase activity DIA-2 16-Dec-15 2015_12 FBgn0058409 CG40409 http://flybase.net/reports/FBgn0058409.html FBan0040409 protein_coding_gene 16-Dec-15 2015_12 FBgn0038654 CG14298 http://flybase.net/reports/FBgn0038654.html protein_coding_gene "0004867=serine-type endopeptidase inhibitor activity, 0030414=peptidase inhibitor activity" "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG14298 16-Dec-15 2015_12 viable FBgn0066071 Su(var)2-15 Su(var)2-15 http://flybase.net/reports/FBgn0066071.html gene 16-Dec-15 2015_12 FBgn0001479 l(1)9Fg lethal (1) 9Fg http://flybase.net/reports/FBgn0001479.html gene "l(1)v207, l(1)BP3, l(1)v40, l(1)v363, l(1)v103, l(1)v172, l(1)v205, l(1)v5" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" FBgn0011811 l(3)s3246 lethal (3) s3246 http://flybase.net/reports/FBgn0011811.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065045 spd slow-phase-defective http://flybase.net/reports/FBgn0065045.html gene 16-Dec-15 2015_12 FBgn0004995 crisp crisp http://flybase.net/reports/FBgn0004995.html gene cr 16-Dec-15 2015_12 "visible,recessive,viable" macrochaeta FBgn0022979 rrpB reduced receptor potential B http://flybase.net/reports/FBgn0022979.html gene 16-Dec-15 2015_12 FBgn0031773 Fbw5 F-box and WD repeat domain containing 5 http://flybase.net/reports/FBgn0031773.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0005515=protein binding" "0045732=positive regulation of protein catabolic process, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process" "0019005=SCF ubiquitin ligase complex, 0080008=Cul4-RING E3 ubiquitin ligase complex" "dFbw5, CG9144, FBgn 31773, FBXW2" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001810=F-box domain, IPR001680=WD40 repeat" CG9144 16-Dec-15 2015_12 ENSDARG00000005642(fbxw5) ENSXETG00000003951(FBXW5) ENSMUSG00000015095(Fbxw5) ENSG00000159069(FBXW5) "viable,visible" "chaeta,supernumerary" DRSC29431 K 0.708787475 0.142056538 0.929483605 -0.69605949 1.52389324 -0.083941674 FBgn0029860 CG15891 http://flybase.net/reports/FBgn0029860.html "FBgn0052918, FBtr0070926, FBpp0070887, FBtr0070927, FBpp0070888, FBtr0070928, FBpp0070889" protein_coding_gene "CG32918, CG15892" IPR023340=UMA domain CG15891 16-Dec-15 2015_12 "viable,fertile" FBgn0259329 C573 http://flybase.net/reports/FBgn0259329.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta" FBgn0040687 CG14645 http://flybase.net/reports/FBgn0040687.html FBan0014645 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14645 16-Dec-15 2015_12 viable FBgn0038292 CG3987 http://flybase.net/reports/FBgn0038292.html FBgn0044657 protein_coding_gene 0007498=mesoderm development anon-WO0140519.215 CG3987 16-Dec-15 2015_12 "viable,fertile" FBgn0266802 CR45264 http://flybase.net/reports/FBgn0266802.html non_protein_coding_gene CR45264 16-Dec-15 2015_12 FBgn0013612 l(3)L0021 lethal (3) L0021 http://flybase.net/reports/FBgn0013612.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0045770 S-Lap3 Sperm-Leucylaminopeptidase 3 http://flybase.net/reports/FBgn0045770.html "FBgn0036084, FBgn0044543, FBgn0052063" protein_coding_gene "0004177=aminopeptidase activity, 0030145=manganese ion binding, 0008235=metalloexopeptidase activity" 0006508=proteolysis 0005737=cytoplasm "anon-WO0140519.83, CG8040, S-LAP 3, BEST:LP10167, Sperm-LeucylAminoPeptidase 3, lincRNA.S4635, CG32063" "IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal, IPR011356=Leucine aminopeptidase/peptidase B" CG32063 16-Dec-15 2015_12 viable FBgn0027507 CG1344 http://flybase.net/reports/FBgn0027507.html protein_coding_gene "0004672=protein kinase activity, 0016301=kinase activity" 0005737=cytoplasm BcDNA:LD22679 "IPR021133=HEAT, type 2, IPR011989=Armadillo-like helical, IPR011009=Protein kinase-like domain, IPR016024=Armadillo-type fold" CG1344 16-Dec-15 2015_12 ENSDARG00000027046(scyl3) ENSXETG00000004735(SCYL3) ENSMUSG00000026584(Scyl3) ENSG00000000457(SCYL3) FBgn0000873 fs(1)M70 female sterile (1) M70 http://flybase.net/reports/FBgn0000873.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0051830 CG31830 http://flybase.net/reports/FBgn0051830.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011721 TB9-3 TB9-3 http://flybase.net/reports/FBgn0011721.html gene 16-Dec-15 2015_12 FBgn0266875 CR45336 http://flybase.net/reports/FBgn0266875.html non_protein_coding_gene CR45336 16-Dec-15 2015_12 FBgn0051810 CG31810 http://flybase.net/reports/FBgn0051810.html FBgn0062454 protein_coding_gene 0016229=steroid dehydrogenase activity 0008202=steroid metabolic process BcDNA:RE06583 "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG31810 16-Dec-15 2015_12 YBR159W(IFA38) ENSMUSG00000034189(Hsdl1) ENSG00000103160(HSDL1) FBgn0035164 CG13901 http://flybase.net/reports/FBgn0035164.html protein_coding_gene IPR026224=Protein DPCD CG13901 16-Dec-15 2015_12 ENSDARG00000060501(dpcd) ENSMUSG00000041035(Dpcd) ENSG00000166171(DPCD) viable FBgn0062570 Mod(var)E1451 Mod(var)E1451 http://flybase.net/reports/FBgn0062570.html gene 0006342=chromatin silencing E1451 16-Dec-15 2015_12 "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0259379 C767 http://flybase.net/reports/FBgn0259379.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0035295 Cnb Centrobin http://flybase.net/reports/FBgn0035295.html FBgn0027777 protein_coding_gene "0007099=centriole replication, 0031024=interphase microtubule organizing center assembly, 0071539=protein localization to centrosome" 0005814=centriole "anon-62BCa, cDNA C, CG5690, centrobin, cnb" CG5690 16-Dec-15 2015_12 ENSMUSG00000032782(Cntrob) "mitotic cell cycle defective,viable" "centrioleED4284),embryonic/larval neuroblast,embryonic/larval neuroblast | larval stage,centrosomeunspecified,centriole" FBgn0265461 jurka http://flybase.net/reports/FBgn0265461.html gene 16-Dec-15 2015_12 memory defective FBgn0265843 CR44632 http://flybase.net/reports/FBgn0265843.html non_protein_coding_gene lincRNA.355 CR44632 16-Dec-15 2015_12 FBgn0085376 CG34347 http://flybase.net/reports/FBgn0085376.html "FBgn0039841, FBgn0039842" protein_coding_gene "0008092=cytoskeletal protein binding, 0003779=actin binding" 0005856=cytoskeleton "CG11339, EST:LP08211, CG15566, LP8211" "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR018980=FERM, C-terminal PH-like domain, IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR029071=Ubiquitin-related domain, IPR018979=FERM, N-terminal, IPR000299=FERM domain, IPR014847=FERM adjacent (FA), IPR019749=Band 4.1 domain" CG34347 16-Dec-15 2015_12 ENSDARG00000044419 WBGene00001490(frm-3) ENSXETG00000016772(FRMD3) viable FBgn0265438 orb::orb2 http://flybase.net/reports/FBgn0265438.html engineered_fusion_gene 16-Dec-15 2015_12 lethal FBgn0010128 l(1)ts445b lethal (1) ts445b http://flybase.net/reports/FBgn0010128.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0052312 tRNA:CR32312 transfer RNA:CR32312 http://flybase.net/reports/FBgn0052312.html FBgn0060272 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna12-CysGCA, tRNA:C:GCA:AE002584-a, AE002584.trna12-CysGCA, CR32312" CR32312 16-Dec-15 2015_12 FBgn0250742 l(3)S051513 lethal (3) S051513 http://flybase.net/reports/FBgn0250742.html gene l(3)s051513 16-Dec-15 2015_12 lethal FBgn0262115 CG17683 http://flybase.net/reports/FBgn0262115.html "FBgn0040002, FBan0017683, FBgn0067364, FBgn0067361, FBgn0067365" protein_coding_gene "0016226=iron-sulfur cluster assembly, 0022008=neurogenesis" "l(2)NC37, l(2)NC38, lethal (2) NC37, NAR1p, l(2)NC70, lethal (2) NC38, NC38, NC37, NC70, lethal (2) NC70" "IPR004108=Iron hydrogenase, large subunit, C-terminal, IPR009016=Iron hydrogenase, IPR003149=Iron hydrogenase, small subunit" CG17683 16-Dec-15 2015_12 "ENSDARG00000062216(narfl),ENSDARG00000071319(LOC100151337),ENSDARG00000024184(narf)" YNL240C(NAR1) WBGene00021902(oxy-4) ENSXETG00000007191(NARFL) ENSMUSG00000002280(Narfl) ENSG00000103245(NARFL) FBgn0005370 wh whiskers http://flybase.net/reports/FBgn0005370.html gene 16-Dec-15 2015_12 visible vibrissae FBgn0023467 anon-56Ca anon-56Ca http://flybase.net/reports/FBgn0023467.html gene 16-Dec-15 2015_12 adult stage | male FBgn0051875 CG31875 http://flybase.net/reports/FBgn0051875.html "FBgn0032173, FBgn0061444" protein_coding_gene "Desr, CG5831, BcDNA:AT29184, Drosophila Elm2-Sant retrogene" "IPR000949=ELM2 domain, IPR001005=SANT/Myb domain" CG31875 16-Dec-15 2015_12 viable FBgn0265483 BG02419 http://flybase.net/reports/FBgn0265483.html gene 16-Dec-15 2015_12 sleep defective FBgn0001555 l(1)19Ba lethal (1) 19Ba http://flybase.net/reports/FBgn0001555.html gene 16-Dec-15 2015_12 lethal FBgn0022098 l(2)k07204 lethal (2) k07204 http://flybase.net/reports/FBgn0022098.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028833 Dak1 Dak1 http://flybase.net/reports/FBgn0028833.html FBgn0062096 protein_coding_gene "0004127=cytidylate kinase activity, 0009041=uridylate kinase activity, 0005524=ATP binding" "0006139=nucleobase-containing compound metabolic process, 0006221=pyrimidine nucleotide biosynthetic process, 0006207='de novo' pyrimidine nucleobase biosynthetic process" "0005737=cytoplasm, 0005634=nucleus" "Dm.UMP-CMP kinase, anon-WO0118547.320, Dak1L, CG6092, dak1" "IPR000850=Adenylate kinase/UMP-CMP kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006266=UMP-CMP kinase" CG6092 16-Dec-15 2015_12 ENSDARG00000019924(cmpk) YKL024C(URA6) "WBGene00009575(F40F8.1),WBGene00007812(C29F7.3)" ENSXETG00000016340(cmpk) ENSMUSG00000028719(Cmpk1) ENSG00000162368(CMPK1) "viable,fertile" FBgn0024352 Hop Hsp70/Hsp90 organizing protein homolog http://flybase.net/reports/FBgn0024352.html FBgn0022263 protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding "HOP, Sti1, Hsp70(Hsp90) organizing protein, hop, dhop, dmSTI1, Hsp70/Hsp90 organizing protein homolog, EP(2)0418, dSTI1, CG2720, dHop, stress inducible protein 1, l(2)k00616, Hsp70/Hsp90 organizing protein, Hsp70-Hsp90 organizing protein" "IPR001440=Tetratricopeptide repeat 1, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR006636=Heat shock chaperonin-binding, IPR011990=Tetratricopeptide-like helical domain" CG2720 16-Dec-15 2015_12 ENSDARG00000004906(stip1) YOR027W(STI1) WBGene00019983(sti-1) ENSXETG00000007189(stip1) ENSMUSG00000024966(Stip1) ENSG00000168439(STIP1) "lethal,recessive,wild-type,viable" FBgn0032350 CG6287 http://flybase.net/reports/FBgn0032350.html protein_coding_gene "0051287=NAD binding, 0004617=phosphoglycerate dehydrogenase activity" 0055114=oxidation-reduction process GH26 "IPR006140=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040=NAD(P)-binding domain, IPR029752=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1, IPR006139=D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain" CG6287 16-Dec-15 2015_12 ENSDARG00000001873(phgdh) "YER081W(SER3),YIL074C(SER33)" WBGene00007836(C31C9.2) ENSXETG00000008530(phgdh) ENSMUSG00000053398(Phgdh) ENSG00000092621(PHGDH) viable FBgn0015904 ara araucan http://flybase.net/reports/FBgn0015904.html FBgn0014195 protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0042693=muscle cell fate commitment, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0006352=DNA-templated transcription, initiation, 0007474=imaginal disc-derived wing vein specification, 0007476=imaginal disc-derived wing morphogenesis, 0035310=notum cell fate specification, 0045317=equator specification, 0045893=positive regulation of transcription, DNA-templated, 0001745=compound eye morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "Ara, IRO-C, iro, iroquois-complex, Iro-C, Iro, Iroquois, iro-C, iroquois, Araucan, Iroquis complex, iroquois gene complex, IroC, CG10571, Aracucan" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR008422=Homeobox KN domain" CG10571 16-Dec-15 2015_12 ENSDARG00000034420(irx6a) "ENSXETG00000002816(Q4LDQ3_XENTR),ENSXETG00000012653(irx2)" "ENSMUSG00000031737(Irx5),ENSMUSG00000031734(Irx3),ENSMUSG00000060969(Irx1),ENSMUSG00000001504(Irx2)" "ENSG00000177508(IRX3),ENSG00000170549(IRX1),ENSG00000176842(IRX5)" " larval stage | third instar , larval stage , embryonic stage -- adult stage , embryonic stage | late , larval stage | second instar , embryonic stage | stage >=11 " " wing vein L5

, dorsal metathoracic disc

, imaginal disc

, embryonic/larval proventriculus

, wing vein L1

, procephalic segment

, mesothoracic pleurum

, tegula

, epidermis | lateral

, alula

, ventral nerve cord

, wing vein L3

" "lethal,recessive,neuroanatomy defective,viable,visible,partially lethal - majority die,female sterile,male sterile,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,some die during pupal stage" "wing vein L5,alula,dorsal multidendritic neuron ddaD,abdominal anterior ventral multidendritic neuron vdaa,wing,macrochaeta,macrochaeta & adult thorax,eye,macrochaeta & scutum,microchaeta,mesothoracic segment,notopleural suture,scutellum,wing vein L1,wing vein L3,sensillum campaniformium of dorsal radius,campaniform sensillum of anterior crossvein,twin sensillum of margin 1,twin sensillum of margin 2,wing hinge,axillary sclerite,dorsal margin photoreceptor,ectopic,ommatidium,maxillary palpus,rostral membrane,adult cuticle,eye disc,somatic clone,photoreceptor cell,antenna,arista,vibrissae,scutum & microchaeta | medial-537.4,wing vein L2,posterior supraalar bristle,anterior supraalar bristle,posterior scutellar bristle,wing vein,sense organ & wing | anteriorC-765,anterior postalar bristle,mesothoracic tergum,dorsal,ventral,embryonic/larval brain" FBgn0063903 Neurodegeneration-9 Neurodegeneration 9 http://flybase.net/reports/FBgn0063903.html gene "ND9, ND10" 16-Dec-15 2015_12 central nervous system FBgn0026244 fret free thinker http://flybase.net/reports/FBgn0026244.html gene 0007067=mitotic nuclear division "thag, think again" 16-Dec-15 2015_12 FBgn0028629 ksh-18 ksh-18 http://flybase.net/reports/FBgn0028629.html gene 16-Dec-15 2015_12 FBgn0261692 T:CBD-WASp Cdc42-binding domain of WASp http://flybase.net/reports/FBgn0261692.html engineered_tag T:CBD 16-Dec-15 2015_12 FBgn0030952 CG12609 http://flybase.net/reports/FBgn0030952.html protein_coding_gene IPR006578=MADF domain CG12609 16-Dec-15 2015_12 viable FBgn0035508 CG15005 http://flybase.net/reports/FBgn0035508.html protein_coding_gene CG15005 16-Dec-15 2015_12 viable FBgn0086129 snama something that sticks like glue http://flybase.net/reports/FBgn0086129.html "FBgn0027522, FBgn0028594" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0004842=ubiquitin-protein transferase activity" "0006915=apoptotic process, 0022008=neurogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0035736=cell proliferation involved in compound eye morphogenesis" 0005634=nucleus "Snama, l(2)rQ313, BCDNA:LD21643, retinoblastoma binding protein 6 family, BcDNA:LD21643, FBgn0086129, mini-me, mnm, CG3231, SNAMA, lethal (2) rQ313" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001878=Zinc finger, CCHC-type, IPR025829=Zinc knuckle CX2CX3GHX4C, IPR001841=Zinc finger, RING-type, IPR014891=DWNN domain" CG3231 16-Dec-15 2015_12 ENSMUSG00000030779(Rbbp6) ENSG00000122257(RBBP6) FBgn0267667 CR46005 http://flybase.net/reports/FBgn0267667.html non_protein_coding_gene CR46005 16-Dec-15 2015_12 FBgn0016720 Reg-6 Rhythmically expressed gene 6 http://flybase.net/reports/FBgn0016720.html gene "Dreg-6, Drosophila Rhythmically expressed gene 6" 16-Dec-15 2015_12 adult stage FBgn0022225 l(2)k03201 lethal (2) k03201 http://flybase.net/reports/FBgn0022225.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0031469 CG18558 http://flybase.net/reports/FBgn0031469.html protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" 0016020=membrane dC1GalT3 IPR003378=Fringe-like CG18558 16-Dec-15 2015_12 viable FBgn0040694 CG14974 http://flybase.net/reports/FBgn0040694.html protein_coding_gene CG14974 16-Dec-15 2015_12 FBgn0264893 CR44084 http://flybase.net/reports/FBgn0264893.html non_protein_coding_gene CR44084 16-Dec-15 2015_12 FBgn0000080 an ancon http://flybase.net/reports/FBgn0000080.html gene 16-Dec-15 2015_12 "visible,recessive" "leg,wing,macrochaeta & abdomen,eye,tergite" FBgn0028599 l(2)W9 lethal (2) W9 http://flybase.net/reports/FBgn0028599.html gene l(2R)W9 16-Dec-15 2015_12 "lethal,recessive" FBgn0005432 fliK flightless K http://flybase.net/reports/FBgn0005432.html "FBgn0000673, FBgn0001865" gene "l(1)9Fc, EM15" 16-Dec-15 2015_12 "lethal,heat sensitive,cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,flightless" FBgn0052027 CR32027 http://flybase.net/reports/FBgn0052027.html FBgn0063078 non_protein_coding_gene "BcDNA:RE02231, CG32027" CR32027 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050382 CG30382 http://flybase.net/reports/FBgn0050382.html protein_coding_gene 0004298=threonine-type endopeptidase activity "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0019773=proteasome core complex, alpha-subunit complex" "Prosalpha1R, Prosalpha6, 30382, Proteasome alpha1 subunit-related, alpha-subunit of 20S proteasome" "IPR001353=Proteasome, subunit alpha/beta, IPR023332=Proteasome A-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000426=Proteasome alpha-subunit, N-terminal domain" CG30382 16-Dec-15 2015_12 "ENSDARG00000013966(zgc:92716),ENSDARG00000019398(psma6a)" YGL011C(SCL1) WBGene00003922(pas-1) ENSXETG00000025884(psma6) ENSMUSG00000021024(Psma6) ENSG00000100902(PSMA6) DRSC29087 IEK -2.335959773 -2.87074977 -1.812772388 -1.150262632 2.154068764 1.458062574 FBgn0002434 l(3)KX209 lethal (3) KX209 http://flybase.net/reports/FBgn0002434.html gene 16-Dec-15 2015_12 lethal peripheral nervous system FBgn0016801 l(1)K3 lethal (1) K3 http://flybase.net/reports/FBgn0016801.html gene K3 16-Dec-15 2015_12 "lethal,recessive" FBgn0259952 Sfp24Bb Seminal fluid protein 24Bb http://flybase.net/reports/FBgn0259952.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "SFP24BB, CG42462, Seminal fluid protein 24Bb" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42462 16-Dec-15 2015_12 FBgn0061508 l(2)24Ab lethal (2) 24Ab http://flybase.net/reports/FBgn0061508.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004158 l(2)51Ea lethal (2) 51Ea http://flybase.net/reports/FBgn0004158.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,lethal,polyphasic,heat sensitive,lethal - all die before end of larval stage,some die during larval stage" FBgn0011224 heph hephaestus http://flybase.net/reports/FBgn0011224.html "FBgn0010798, FBgn0011433, FBgn0029138, FBgn0039884, FBgn0039885, FBgn0051000" protein_coding_gene "0000900=translation repressor activity, nucleic acid binding, 0003730=mRNA 3'-UTR binding, 0008187=poly-pyrimidine tract binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0008587=imaginal disc-derived wing margin morphogenesis, 0000398=mRNA splicing, via spliceosome, 0008103=oocyte microtubule cytoskeleton polarization, 0006974=cellular response to DNA damage stimulus, 0008586=imaginal disc-derived wing vein morphogenesis, 0007291=sperm individualization, 0007319=negative regulation of oskar mRNA translation, 2001020=regulation of response to DNA damage stimulus, 0007286=spermatid development, 0007219=Notch signaling pathway" "0005829=cytosol, 0005737=cytoplasm, 0030529=ribonucleoprotein complex, 0005634=nucleus" "ectopic margin, HEPH, Polypyrimidine Tract Binding protein, CG2094, dmPTB, ptb, ema, Ptb, CG31000, Hephaestus, polypyrimidine tract-binding protein, hnRNP I, l(3)03429, polypyrimidine tract binding protein, Heterogeneous Nuclear RibonucleoProtein I, PTB, dPTB, DmPTB, l(3)j11B9, Heph, CG2290" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006536=HnRNP-L/PTB/hephaestus splicing factor, IPR000504=RNA recognition motif domain" CG31000 16-Dec-15 2015_12 "ENSDARG00000043757(si:dkey-27p1.2),ENSDARG00000019362(ptbp1a),ENSDARG00000031907(ptbp1b),ENSDARG00000015901(ptbp2),ENSDARG00000015230(zgc:113074)" WBGene00004207(ptb-1) "ENSXETG00000002225(ROD1),ENSXETG00000021661(ptbp1),ENSXETG00000018926(PTBP2)" "ENSMUSG00000006498(Ptbp1),ENSMUSG00000028382(Rod1),ENSMUSG00000028134(Ptbp2)" "ENSG00000011304(PTBP1),ENSG00000117569(PTBP2),ENSG00000119314(ROD1)" "viable,fertile,learning defective,lethal,male sterile,recessive,heat sensitive,visible,somatic clone,mitotic cell cycle defective,female fertile" "wing,testis,spermatozoon,individualization stage spermatid,spermatid cyst,elongation stage spermatid,germline cell,male,macrochaeta,wing vein,cell autonomous,somatic clone,wing margin,ectopic,embryonic head,germline clone,trichogen cell,mesothoracic tergum" DRSC14085 IE -0.910237949 -1.539103529 -0.008490841 -1.831969216 -0.369370127 0.374456334 FBgn0263333 CR43414 http://flybase.net/reports/FBgn0263333.html non_protein_coding_gene lincRNA.205 CR43414 16-Dec-15 2015_12 FBgn0051352 Unc-115a http://flybase.net/reports/FBgn0051352.html "FBgn0037733, FBgn0044663, FBgn0063633" protein_coding_gene "0003779=actin binding, 0008270=zinc ion binding" "0007411=axon guidance, 0007010=cytoskeleton organization, 0072499=photoreceptor cell axon guidance" "Dunc-115, anon-WO0140519.21, unc-115, CG9489, CG31352, dunc-115" "IPR003128=Villin headpiece, IPR001781=Zinc finger, LIM-type" CG31352 16-Dec-15 2015_12 ENSDARG00000029772(zgc:158673) WBGene00006839(unc-115) ENSXETG00000011610(ABLIM2) "ENSMUSG00000025085(Ablim1),ENSMUSG00000032735(Ablim3),ENSMUSG00000029095(Ablim2)" "ENSG00000173210(ABLIM3),ENSG00000099204(ABLIM1),ENSG00000163995(ABLIM2)" "viable,visible,fertile,neuroanatomy defective" "mesothoracic tergum,lamina plexus,eye photoreceptor cell,segmental nerve,embryonic ventral neuromere,longitudinal connective" FBgn0040609 CG3348 http://flybase.net/reports/FBgn0040609.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG3348 16-Dec-15 2015_12 viable DRSC15480 I 1.570023063 -0.125233726 -1.274720235 0.185065206 0.245618456 -0.329843495 FBgn0267476 CR45826 http://flybase.net/reports/FBgn0267476.html non_protein_coding_gene CR45826 16-Dec-15 2015_12 FBgn0053158 CG33158 http://flybase.net/reports/FBgn0053158.html "FBgn0036631, FBgn0036634" protein_coding_gene "0005525=GTP binding, 0003746=translation elongation factor activity, 0003924=GTPase activity" 0006414=translational elongation "0005850=eukaryotic translation initiation factor 2 complex, 0005829=cytosol" "CG4638, CG10162" "IPR000640=Translation elongation factor EFG, V domain, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR005225=Small GTP-binding protein domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR009022=Elongation factor G, III-V domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG33158 16-Dec-15 2015_12 WBGene00010732(K10C3.5) ENSXETG00000015701() ENSMUSG00000038563(Eftud1) ENSG00000140598(EFTUD1) "viable,fertile,song defective" FBgn0053367 5SrRNA:CR33367 5SrRNA:CR33367 http://flybase.net/reports/FBgn0053367.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33367 CR33367 16-Dec-15 2015_12 FBgn0060754 l(3)S064316a lethal (3) S064316a http://flybase.net/reports/FBgn0060754.html gene 0643/16 16-Dec-15 2015_12 lethal FBgn0031279 CG3544 http://flybase.net/reports/FBgn0031279.html protein_coding_gene 0004856=xylulokinase activity "0046835=carbohydrate phosphorylation, 0005997=xylulose metabolic process" 0070062=extracellular exosome "IPR018485=Carbohydrate kinase, FGGY, C-terminal, IPR018484=Carbohydrate kinase, FGGY, N-terminal" CG3544 16-Dec-15 2015_12 ENSDARG00000043260(zgc:64119) YGR194C(XKS1) WBGene00011147(R08D7.7) ENSXETG00000012361() ENSMUSG00000035769(Xylb) ENSG00000093217(XYLB) viable FBgn0028030 l(3)S102702a lethal (3) S102702a http://flybase.net/reports/FBgn0028030.html gene "1027/02, l(3)S102702" 16-Dec-15 2015_12 "lethal,recessive" FBgn0086472 RpS25 Ribosomal protein S25 http://flybase.net/reports/FBgn0086472.html "FBgn0010413, FBgn0005282, FBgn0002621, FBgn0025297" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "Minute (3) 86D, M(3)s[32], anon-EST:Posey260, S25, M(3)S32, M(3)S31, RpS31, CG6684, M(3)86D, RpS25, D25, Minute (3) S32, Rp S25" IPR004977=Ribosomal protein S25 CG6684 16-Dec-15 2015_12 ENSDARG00000041811(rps25) "YGR027C(RPS25A),YLR333C(RPS25B)" WBGene00004494(rps-25) "ENSXETG00000026415(Q6DET7_XENTR),ENSXETG00000022685()" "ENSMUSG00000009927(Rps25),ENSMUSG00000063739(Gm4963)" "ENSG00000185641,ENSG00000118181(RPS25)" DRSC16837 I 1.760477892 0.057942348 0.169615307 -0.055630064 -0.185561351 0.767995142 FBgn0028105 l(3)S071501 lethal (3) S071501 http://flybase.net/reports/FBgn0028105.html gene 0715/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0036936 CG14185 http://flybase.net/reports/FBgn0036936.html protein_coding_gene CT33794 IPR001611=Leucine-rich repeat CG14185 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0014262 l(2)X lethal (2) X http://flybase.net/reports/FBgn0014262.html gene 16-Dec-15 2015_12 FBgn0001252 im interrupted margin http://flybase.net/reports/FBgn0001252.html gene 16-Dec-15 2015_12 "visible,female sterile,viable,male,reduced" "wing vein,costal vein,eye,macrochaeta,wing" FBgn0024229 hnc13 hnc13 http://flybase.net/reports/FBgn0024229.html FBgn0026237 gene 0000122=negative regulation of transcription from RNA polymerase II promoter h-NC13 16-Dec-15 2015_12 FBgn0027171 l(2)B2 lethal (2) B2 http://flybase.net/reports/FBgn0027171.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0027185 l(2)60A-H lethal (2) 60A-H http://flybase.net/reports/FBgn0027185.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0086659 snoRNA:ë¬18S-176 snoRNA:ë¬18S-176 http://flybase.net/reports/FBgn0086659.html "FBgn0065068, FBgn0083043, FBgn0053913" snoRNA_gene 0005730=nucleolus "CR33913, Dm-314, Psi 18S-176(SnoR314), snoRNA:314, psi18s-176" CR33913 16-Dec-15 2015_12 FBgn0060741 l(3)S066610b lethal (3) S066610b http://flybase.net/reports/FBgn0060741.html gene 0666/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0017430 Nelf-E Negative elongation factor E http://flybase.net/reports/FBgn0017430.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0034244=negative regulation of transcription elongation from RNA polymerase II promoter, 0022008=neurogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007070=negative regulation of transcription from RNA polymerase II promoter during mitosis" "0005634=nucleus, 0017053=transcriptional repressor complex, 0032021=NELF complex" "cg5994, NELF, anonymous-66Da, CG5994, NELF-E, unnamed, anon-66Da, NelfE, Nelf-e, negative elongation factor, dNelf-E" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG5994 16-Dec-15 2015_12 ENSXETG00000010931(RDBP) pupal stage&&adult stage "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,germline clone,maternal effect" "wing,adult thorax,adult head,ommatidium,second segment of antenna,third segment of antenna,arista,tarsal segment,embryonic/larval hemocyte | third instar larval stage,ganglion mother cell,trichogen cell" FBgn0036828 CG6841 http://flybase.net/reports/FBgn0036828.html protein_coding_gene 0003723=RNA binding "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus" "BcDNA:LD43276, Prp6" "IPR003107=HAT (Half-A-TPR) repeat, IPR010491=PRP1 splicing factor, N-terminal, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG6841 16-Dec-15 2015_12 ENSDARG00000014500(c20orf14) YBR055C(PRP6) WBGene00013343(Y59A8B.6) ENSXETG00000012054(BC091611.1) ENSMUSG00000002455(Prpf6) ENSG00000101161(PRPF6) "lethal,neuroanatomy defective,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,antenna,tarsal segment,unguis,pulvillus" DRSC21773 IE 0.391715312 2.018223583 1.4341235 2.519244203 -0.377498115 -1.230411843 FBgn0051288 CG31288 http://flybase.net/reports/FBgn0051288.html FBgn0039318 protein_coding_gene CG13665 "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG31288 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0283432 CG46275 http://flybase.net/reports/FBgn0283432.html protein_coding_gene CG46275 16-Dec-15 2015_12 FBgn0267740 CR46071 http://flybase.net/reports/FBgn0267740.html non_protein_coding_gene Mgn635 CR46071 16-Dec-15 2015_12 FBgn0040392 CG14050 http://flybase.net/reports/FBgn0040392.html FBgn0029610 protein_coding_gene 0003677=DNA binding "EG:BACH48C10.1, H48C10.1" "IPR003656=Zinc finger, BED-type" CG14050 16-Dec-15 2015_12 viable FBgn0043074 HF-BXC Homing Fragment http://flybase.net/reports/FBgn0043074.html region 16-Dec-15 2015_12 FBgn0030259 CG1545 http://flybase.net/reports/FBgn0030259.html "FBgn0027708, FBgn0063285" protein_coding_gene "BcDNA:GH01560, anon-EST:Posey256" CG1545 16-Dec-15 2015_12 viable FBgn0260967 CG42590 http://flybase.net/reports/FBgn0260967.html protein_coding_gene CG42590 16-Dec-15 2015_12 FBgn0043365 EP2146a EP2146a http://flybase.net/reports/FBgn0043365.html gene EP(2)2146 16-Dec-15 2015_12 visible "scutellar bristle,tormogen cell,trichogen cell,ectopic,embryonic/larval salivary gland" FBgn0005376 x6 x6 http://flybase.net/reports/FBgn0005376.html gene 16-Dec-15 2015_12 FBgn0260101 2L0128 http://flybase.net/reports/FBgn0260101.html gene 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,somatic clone" FBgn0051963 tRNA:CR31963 transfer RNA:CR31963 http://flybase.net/reports/FBgn0051963.html FBgn0060013 tRNA_gene "0033416=UGG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:W:CCA:AE002638, AE002638.trna1-TrpCCA, chr2L.trna34-TrpCCA, CR31963" CR31963 16-Dec-15 2015_12 FBgn0035412 CG14957 http://flybase.net/reports/FBgn0035412.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14957 16-Dec-15 2015_12 viable FBgn0023126 anon-10Acc anon-10Acc http://flybase.net/reports/FBgn0023126.html gene 22 16-Dec-15 2015_12 FBgn0003376 Sgs6 Salivary gland secretion 6 http://flybase.net/reports/FBgn0003376.html gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "sgs6, SGS-6, Sgs-6, Sgs" 16-Dec-15 2015_12 larval stage | late third instar larval stage embryonic/larval salivary gland

FBgn0016778 anon-77Bb anon-77Bb http://flybase.net/reports/FBgn0016778.html gene "C, transcript C" 16-Dec-15 2015_12 FBgn0040815 CG14114 http://flybase.net/reports/FBgn0040815.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085222 CG34193 http://flybase.net/reports/FBgn0085222.html protein_coding_gene CG34193 16-Dec-15 2015_12 FBgn0037911 CG10898 http://flybase.net/reports/FBgn0037911.html FBgn0062122 protein_coding_gene 0016787=hydrolase activity 0006281=DNA repair anon-WO0118547.280 "IPR015797=NUDIX hydrolase domain-like, IPR020084=NUDIX hydrolase, conserved site, IPR020476=NUDIX hydrolase, IPR000086=NUDIX hydrolase domain" CG10898 16-Dec-15 2015_12 ENSDARG00000041576(nudt18) WBGene00003578(ndx-1) ENSXETG00000010538(NUDT18) ENSMUSG00000045211(Nudt18) "viable,fertile" FBgn0065448 l(2)SH1405 lethal (2) SH1405 http://flybase.net/reports/FBgn0065448.html gene l(2)SH2 1405 16-Dec-15 2015_12 "lethal,recessive" FBgn0065391 l(2)SH1627 lethal (2) SH1627 http://flybase.net/reports/FBgn0065391.html gene l(2)SH2 1627 16-Dec-15 2015_12 "lethal,recessive" FBgn0026211 l(4)102CDh lethal (4) 102CDh http://flybase.net/reports/FBgn0026211.html gene "102CDh, l(4)10, 10" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005682 rdgD retinal degeneration D http://flybase.net/reports/FBgn0005682.html gene 16-Dec-15 2015_12 "eye,ommatidium,eye photoreceptor cell,retina" FBgn0267650 pre-mod(mdg4)-AA http://flybase.net/reports/FBgn0267650.html protein_coding_gene CG45988 CG45988 16-Dec-15 2015_12 FBgn0053405 5SrRNA:CR33405 5SrRNA:CR33405 http://flybase.net/reports/FBgn0053405.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33405 CR33405 16-Dec-15 2015_12 FBgn0277424 l(3)psg21 http://flybase.net/reports/FBgn0277424.html gene psg21 16-Dec-15 2015_12 FBgn0005382 ggy groggy http://flybase.net/reports/FBgn0005382.html gene 16-Dec-15 2015_12 "paralytic,temperature conditional,neurophysiology defective" FBgn0014120 anon-96Fe anon-96Fe http://flybase.net/reports/FBgn0014120.html gene A transcript 16-Dec-15 2015_12 larval stage eye-antennal disc

FBgn0031037 CG14207 http://flybase.net/reports/FBgn0031037.html protein_coding_gene "0010506=regulation of autophagy, 0010998=regulation of translational initiation by eIF2 alpha phosphorylation, 0006497=protein lipidation" "0030018=Z disc, 0005829=cytosol, 0005654=nucleoplasm" "HspB8, CG14207, Hsp20-like protein, small heat shock protein hsp20 family, dHspB8" "IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain, IPR031107=Small heat shock protein HSP20, IPR008978=HSP20-like chaperone" CG14207 16-Dec-15 2015_12 WBGene00002023(hsp-25) "viable,lethal" FBgn0042201 Nplp3 Neuropeptide-like precursor 3 http://flybase.net/reports/FBgn0042201.html "FBgn0036604, FBgn0062957" protein_coding_gene 0005184=neuropeptide hormone activity 0007218=neuropeptide signaling pathway 0005576=extracellular region "neuropeptide-like precursor 3, VVIamide, NPLP3, SHA peptide, SHA, CG13061, nplp3, VVIamide peptide, BcDNA:RH16169, CG18502" CG13061 16-Dec-15 2015_12 "viable,fertile" DRSC09944 I -0.938751205 1.582575417 0.183768495 0.563328418 -0.031505594 -0.422396686 FBgn0010093 Su(vg)E6 Suppressor of vestigial E6 http://flybase.net/reports/FBgn0010093.html gene vg[[EMS6]] 16-Dec-15 2015_12 FBgn0052582 CR32582 http://flybase.net/reports/FBgn0052582.html FBgn0062842 non_protein_coding_gene "CG32582, mdcds_55373, BcDNA:SD27303" CR32582 16-Dec-15 2015_12 "viable,fertile" FBgn0037680 CG8121 http://flybase.net/reports/FBgn0037680.html protein_coding_gene dmCG8121 CG8121 16-Dec-15 2015_12 lethal FBgn0052100 CG32100 http://flybase.net/reports/FBgn0052100.html "FBgn0036269, FBgn0036270" protein_coding_gene 0042332=gravitaxis "CG10429, CG18638" CG32100 16-Dec-15 2015_12 "gravitaxis defective,viable" FBgn0265841 CR44630 http://flybase.net/reports/FBgn0265841.html non_protein_coding_gene CR44630 16-Dec-15 2015_12 FBgn0085822 CR41613 http://flybase.net/reports/FBgn0085822.html FBan0041613 rRNA_gene CR41613 16-Dec-15 2015_12 FBgn0029133 REG REG http://flybase.net/reports/FBgn0029133.html FBgn0030461 protein_coding_gene "0061133=endopeptidase activator activity, 0004866=endopeptidase inhibitor activity" "0000398=mRNA splicing, via spliceosome, 2000045=regulation of G1/S transition of mitotic cell cycle, 0061136=regulation of proteasomal protein catabolic process" "0005730=nucleolus, 0008537=proteasome activator complex, 0071013=catalytic step 2 spliceosome, 0005703=polytene chromosome puff, 0005634=nucleus, 0005705=polytene chromosome interband, 0005737=cytoplasm, 0071011=precatalytic spliceosome" "REGgamma, DmREGgamma, dREGgamma, dReggamma, CG1591, dREG" "IPR003186=Proteasome activator pa28, C-terminal domain, IPR003185=Proteasome activator pa28, N-terminal domain, IPR009077=Proteasome activator pa28" CG1591 16-Dec-15 2015_12 ENSDARG00000012234(psme3) WBGene00013435(Y66D12A.9) ENSXETG00000012591(PSME3) ENSMUSG00000078652(Psme3) ENSG00000131467(PSME3) "viable,fertile" FBgn0020265 oap ombre-a-paupieres http://flybase.net/reports/FBgn0020265.html gene 16-Dec-15 2015_12 FBgn0065338 l(2)SH1844 lethal (2) SH1844 http://flybase.net/reports/FBgn0065338.html gene l(2)SH2 1844 16-Dec-15 2015_12 "lethal,recessive" FBgn0003363 sesF stress-sensitive F http://flybase.net/reports/FBgn0003363.html gene 16-Dec-15 2015_12 uncoordinated FBgn0061473 34-20 34-20 http://flybase.net/reports/FBgn0061473.html gene 16-Dec-15 2015_12 FBgn0022381 Pt-10 Larval protein-10 http://flybase.net/reports/FBgn0022381.html gene 16-Dec-15 2015_12 FBgn0265814 CR44603 http://flybase.net/reports/FBgn0265814.html non_protein_coding_gene lincRNA.10 CR44603 16-Dec-15 2015_12 FBgn0067359 l(2)NC85 lethal (2) NC85 http://flybase.net/reports/FBgn0067359.html gene NC85 16-Dec-15 2015_12 "lethal,recessive" FBgn0267287 CR45723 http://flybase.net/reports/FBgn0267287.html non_protein_coding_gene CR45723 16-Dec-15 2015_12 FBgn0002787 Rpn8 Regulatory particle non-ATPase 8 http://flybase.net/reports/FBgn0002787.html FBgn0022065 protein_coding_gene "0000022=mitotic spindle elongation, 0008283=cell proliferation, 0006511=ubiquitin-dependent protein catabolic process, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0022008=neurogenesis, 0007052=mitotic spindle organization" "0005838=proteasome regulatory particle, 0008541=proteasome regulatory particle, lid subcomplex, 0030425=dendrite, 0000502=proteasome complex" "S12, unnamed, l(2)k08003, P26270, RPN8, CG3416, p39B, PRSC_DROME, Rpn8, Mov34" "IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR024969=Rpn11/EIF3F, C-terminal" CG3416 16-Dec-15 2015_12 ENSDARG00000068076 YOR261C(RPN8) WBGene00004464(rpn-8) ENSXETG00000017884(psmd7) ENSMUSG00000039067(Psmd7) ENSG00000103035(PSMD7) adult stage "lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,somatic clone,decreased cell number" "embryonic/larval hemocyte | third instar larval stage,wing,embryonic/larval neuroblast,ganglion mother cell,dendritic arborizing neuron,mushroom body gamma-lobe,somatic clone,neuroblast,adult mushroom body" DRSC04624 IEK -4.600104022 -3.331259077 -6.09037063 -2.616607701 1.433271406 -1.774792707 FBgn0030394 Cpr11A Cuticular protein 11A http://flybase.net/reports/FBgn0030394.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "L12, CG2560" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG2560 16-Dec-15 2015_12 viable FBgn0263413 CR43459 http://flybase.net/reports/FBgn0263413.html non_protein_coding_gene pri-mir-277_mir-34 CR43459 16-Dec-15 2015_12 FBgn0085437 CG34408 http://flybase.net/reports/FBgn0085437.html "FBgn0028486, FBgn0052689" protein_coding_gene 0005096=GTPase activator activity 0051056=regulation of small GTPase mediated signal transduction "BcDNA:GH09358, CG2967, CG32689" IPR000331=Rap GTPase activating protein domain CG34408 16-Dec-15 2015_12 ENSDARG00000016751 WBGene00008430(D2085.5) ENSXETG00000021438(RALGAPB) ENSMUSG00000027652(Ralgapb) ENSG00000170471(RALGAPB) FBgn0033401 CG1968 http://flybase.net/reports/FBgn0033401.html protein_coding_gene 0006891=intra-Golgi vesicle-mediated transport 0017119=Golgi transport complex IPR010490=Conserved oligomeric Golgi complex subunit 6 CG1968 16-Dec-15 2015_12 ENSDARG00000012336(cog6) YNL041C(COG6) WBGene00019481(cogc-6) ENSXETG00000016035(Q6DJ24_XENTR) ENSMUSG00000027742(Cog6) ENSG00000133103(COG6) viable FBgn0045041 l(1)G0302 lethal (1) G0302 http://flybase.net/reports/FBgn0045041.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0010809 l(3)03675 lethal (3) 03675 http://flybase.net/reports/FBgn0010809.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0250828 CR41437 http://flybase.net/reports/FBgn0250828.html "FBan0041437, FBgn0085785, FBgn0027753" non_protein_coding_gene anon-EST:Posey146 16-Dec-15 2015_12 FBgn0266827 CR45289 http://flybase.net/reports/FBgn0266827.html non_protein_coding_gene CR45289 16-Dec-15 2015_12 FBgn0005236 l(3)R45 lethal of Roberts 45 http://flybase.net/reports/FBgn0005236.html gene l(3)B45 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0034663 CG4363 http://flybase.net/reports/FBgn0034663.html FBgn0063113 protein_coding_gene "BcDNA:LP06375, CT14230" IPR008472=Domain of unknown function DUF753 CG4363 16-Dec-15 2015_12 viable FBgn0061052 l(3)S023204a lethal (3) S023204a http://flybase.net/reports/FBgn0061052.html gene 0232/04 16-Dec-15 2015_12 lethal FBgn0250903 lmgA lemming A http://flybase.net/reports/FBgn0250903.html "FBgn0029004, FBgn0010539, FBgn0032056, FBgn0085469, FBan0018042" protein_coding_gene "0008270=zinc ion binding, 0090302=APC-Cdc20 complex activity" "0016567=protein ubiquitination, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0045842=positive regulation of mitotic metaphase/anaphase transition" "0005680=anaphase-promoting complex, 0000151=ubiquitin ligase complex" "LMG, l(2)03424, Apc11, Lemming, CG34440, ORF1, Dromel_CG18042_FBtr0079695_lmg_uORF, Img, lmg, CG18042, APC11, lemming" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR024991=Anaphase-promoting complex subunit 11" CG34440 16-Dec-15 2015_12 ENSDARG00000070333(anapc11) YDL008W(APC11) WBGene00000145(apc-11) ENSMUSG00000025135(Anapc11) ENSG00000215639 "lethal,recessive,neuroanatomy defective,somatic clone,increased cell death,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of prepupal stage,some die during prepupal stage,viable,fertile" "eye,histoblast,neuroblast,somatic clone,embryonic/larval brain,wing disc,intersegmental nerve,anterior fascicle & synapse" FBgn0260495 l(3)2727 http://flybase.net/reports/FBgn0260495.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,dendrite" FBgn0002259 l(3)68Fd lethal (3) 68Fd http://flybase.net/reports/FBgn0002259.html gene "l(3)rsg21, rsg21, rose-gespleten region interval 21" 16-Dec-15 2015_12 lethal FBgn0027778 anon-1Ab anon-1Ab http://flybase.net/reports/FBgn0027778.html gene 1A 16-Dec-15 2015_12 FBgn0027795 CG14785 http://flybase.net/reports/FBgn0027795.html protein_coding_gene EG:BACN32G11.2 IPR011705=BTB/Kelch-associated CG14785 16-Dec-15 2015_12 viable FBgn0011951 tRNA:R:12Ed transfer RNA:arg:12Ed http://flybase.net/reports/FBgn0011951.html "FBgn0011947, FBgn0052617, FBgn0060079" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033431=CGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chrX.trna11-ArgTCG, tRNA:arg12Ed, tRNA[arg], tRNA:arg1, CR32617, tRNA:R1, transfer RNA:arg1, AE002593.trna7-ArgTCG, tRNA-Arg, tRNA:R:TCG:AE002593-e" CR32617 16-Dec-15 2015_12 FBgn0060343 l(3)S143814 lethal (3) S143814 http://flybase.net/reports/FBgn0060343.html gene 1438/14 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0060527 l(3)S101715b lethal (3) S101715b http://flybase.net/reports/FBgn0060527.html gene 1017/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0005035 e(S)r "enhancer of Star, recessive" http://flybase.net/reports/FBgn0005035.html gene "enhancer of Star, S-i, intensifier of Star, e(S)" 16-Dec-15 2015_12 wild-type FBgn0005157 l(2)G129 lethal (2) G129 http://flybase.net/reports/FBgn0005157.html gene 16-Dec-15 2015_12 lethal FBgn0022726 milo milo http://flybase.net/reports/FBgn0022726.html gene 0040007=growth 16-Dec-15 2015_12 FBgn0035423 CG17737 http://flybase.net/reports/FBgn0035423.html "FBgn0025534, FBgn0062453" protein_coding_gene 0003743=translation initiation factor activity "0071456=cellular response to hypoxia, 0006412=translation, 0006413=translational initiation" "anon-EST:Posey272, BcDNA:RE14985" "IPR001950=Translation initiation factor SUI1, IPR005874=Eukaryotic translation initiation factor SUI1" CG17737 16-Dec-15 2015_12 "ENSDARG00000012688(eif1b),ENSDARG00000029445(zgc:56676)" YNL244C(SUI1) "ENSXETG00000000359(sui1),ENSXETG00000025051(TEgg121i05.1)" "ENSMUSG00000035530(Eif1),ENSMUSG00000006941(Eif1b),ENSMUSG00000074046(Gm16378)" "ENSG00000173812(EIF1),ENSG00000114784(EIF1B)" viable FBgn0026204 milou milou http://flybase.net/reports/FBgn0026204.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing disc,wing" FBgn0036597 CG4962 http://flybase.net/reports/FBgn0036597.html protein_coding_gene CT15908 CG4962 16-Dec-15 2015_12 viable FBgn0266776 CR45241 http://flybase.net/reports/FBgn0266776.html non_protein_coding_gene CR45241 16-Dec-15 2015_12 FBgn0266471 gevuinanut http://flybase.net/reports/FBgn0266471.html gene 16-Dec-15 2015_12 lethal "egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell" FBgn0267163 CG45603 http://flybase.net/reports/FBgn0267163.html protein_coding_gene CG45603 16-Dec-15 2015_12 FBgn0083302 E(smoDN)1700 Enhancer of smoDN 1700 http://flybase.net/reports/FBgn0083302.html gene 16-Dec-15 2015_12 FBgn0035643 CG13287 http://flybase.net/reports/FBgn0035643.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG13287 16-Dec-15 2015_12 lethal DRSC09961 I 0.826555674 -1.604250697 -0.786428164 0.639982357 -0.773440048 -0.076948619 FBgn0085700 CG41573 http://flybase.net/reports/FBgn0085700.html FBan0041573 protein_coding_gene 16-Dec-15 2015_12 FBgn0000512 dv divergent http://flybase.net/reports/FBgn0000512.html gene aea 16-Dec-15 2015_12 "visible,semi-sterile" "wing,wing vein" FBgn0065437 l(2)SH1469 lethal (2) SH1469 http://flybase.net/reports/FBgn0065437.html gene l(2)SH2 1469 16-Dec-15 2015_12 "lethal,recessive" FBgn0003398 shp shrimp http://flybase.net/reports/FBgn0003398.html gene 16-Dec-15 2015_12 "viable,male,reduced,male fertile,female fertile,visible,recessive" FBgn0266566 CG45105 http://flybase.net/reports/FBgn0266566.html "FBgn0051291, FBgn0038382, FBgn0038383, FBgn0085304" protein_coding_gene "CG14878, CG34275, CG5552, CG31291" CG45105 16-Dec-15 2015_12 FBgn0060669 l(3)S079304b lethal (3) S079304b http://flybase.net/reports/FBgn0060669.html gene 0793/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0082333 HM801 HM801 http://flybase.net/reports/FBgn0082333.html gene 16-Dec-15 2015_12 FBgn0032707 CG10348 http://flybase.net/reports/FBgn0032707.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0006355=regulation of transcription, DNA-templated" lincRNA.186 "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR030413=Evi1/Prdm16" CG10348 16-Dec-15 2015_12 "ENSG00000136826(KLF4),ENSG00000127528(KLF2)" viable FBgn0261966 huc2L-12 hydroxyurea- and (or) caffeine-sensitive 2L-12 http://flybase.net/reports/FBgn0261966.html gene huc[2L-12] 16-Dec-15 2015_12 "chemical sensitive,somatic clone,lethal" "eye,somatic clone,drug conditional" FBgn0051174 CG31174 http://flybase.net/reports/FBgn0051174.html FBgn0062887 protein_coding_gene BcDNA:SD11171 IPR009991=Dynactin subunit p22 CG31174 16-Dec-15 2015_12 FBgn0031457 CG3077 http://flybase.net/reports/FBgn0031457.html protein_coding_gene 0035091=phosphatidylinositol binding DmSNX21 IPR001683=Phox homologous domain CG3077 16-Dec-15 2015_12 "ENSDARG00000062770(zgc:153354),ENSDARG00000051755(LOC794759)" ENSXETG00000024567(TEgg006g23.1) "ENSMUSG00000050373(Snx21),ENSMUSG00000031662(Snx20)" "ENSG00000124104(SNX21),ENSG00000167208(SNX20)" viable FBgn0041169 anon-82Aa anon-82Aa http://flybase.net/reports/FBgn0041169.html gene cB151 16-Dec-15 2015_12 " embryonic stage | early , embryonic stage | stage 8-15 " "

ubiquitous , mesoderm

" FBgn0086171 nkd::Mmus\Nkd1 http://flybase.net/reports/FBgn0086171.html engineered_fusion_gene 16-Dec-15 2015_12 visible sternite FBgn0058098 CG40098 http://flybase.net/reports/FBgn0058098.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260019 sancho-panza sancho panza http://flybase.net/reports/FBgn0260019.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0259321 EP-323 http://flybase.net/reports/FBgn0259321.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0264979 CG4267 http://flybase.net/reports/FBgn0264979.html "FBgn0031405, FBgn0051686" protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "Dmel_CG4267, CG31686" "IPR000734=Triacylglycerol lipase family, IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold" CG4267 16-Dec-15 2015_12 DRSC00102 IE -0.497545512 -2.894494065 -0.610660615 -4.632974162 -1.167931397 -0.067808142 FBgn0032726 CG10621 http://flybase.net/reports/FBgn0032726.html "FBgn0043797, FBgn0044752" protein_coding_gene "0016205=selenocysteine methyltransferase activity, 0008898=S-adenosylmethionine-homocysteine S-methyltransferase activity" "selenocysteine methyltransferase, BEST:LD26123, anon-WO0140519.13" IPR003726=Homocysteine-binding domain CG10621 16-Dec-15 2015_12 ENSDARG00000034430(zgc:172121) "YPL273W(SAM4),YLL062C(MHT1)" WBGene00020491(T13G4.4) ENSXETG00000025468(BC059753.1) "ENSMUSG00000069324,ENSMUSG00000082293,ENSMUSG00000066252,ENSMUSG00000042118(Bhmt2)" "ENSG00000145692(BHMT),ENSG00000132840(BHMT2)" viable FBgn0030431 CG4407 http://flybase.net/reports/FBgn0030431.html protein_coding_gene 0003919=FMN adenylyltransferase activity 0008152=metabolic process Fad1 "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR002500=Phosphoadenosine phosphosulphate reductase" CG4407 16-Dec-15 2015_12 YDL045C(FAD1) WBGene00011271(R53.1) viable FBgn0040928 CR15345 http://flybase.net/reports/FBgn0040928.html FBgn0064877 pseudogene_attribute "BcDNA:RE52922, CG15345" CR15345 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0259410 EP-P http://flybase.net/reports/FBgn0259410.html gene 16-Dec-15 2015_12 visible wing FBgn0001548 l(1)16Fb lethal (1) 16Fb http://flybase.net/reports/FBgn0001548.html gene "F-a transcription unit, F-a, I[[2]], MEII, ME-II" 16-Dec-15 2015_12 "wild-type,lethal,non-rescuable maternal effect,visible,recessive,body color defective,dominant,polyphasic" "gastrula embryo,wing vein,adult cuticle,macrochaeta" FBgn0027184 l(2)60A-I lethal (2) 60A-I http://flybase.net/reports/FBgn0027184.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0086393 BG02169 http://flybase.net/reports/FBgn0086393.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0004762 l(3)89Cc lethal (3) 89Cc http://flybase.net/reports/FBgn0004762.html gene 16-Dec-15 2015_12 lethal FBgn0022376 Pt-15 Larval protein-15 http://flybase.net/reports/FBgn0022376.html gene PT-15 16-Dec-15 2015_12 FBgn0040345 CG3708 http://flybase.net/reports/FBgn0040345.html FBgn0029542 protein_coding_gene 0042393=histone binding 0006334=nucleosome assembly 0005634=nucleus "152685_at, EG:BACR7A4.18" IPR002164=Nucleosome assembly protein (NAP) CG3708 16-Dec-15 2015_12 YKR048C(NAP1) WBGene00017075(D2096.8) viable FBgn0001431 l(1)7Aa lethal (1) 7Aa http://flybase.net/reports/FBgn0001431.html gene "RA62, jnR1, l(1)inR1, l(1)jnR1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038676 CG6026 http://flybase.net/reports/FBgn0038676.html protein_coding_gene CG6026 16-Dec-15 2015_12 "lethal,viable" FBgn0002270 l(3)69Bb lethal (3) 69Bb http://flybase.net/reports/FBgn0002270.html gene "rose-gespleten region interval 32, l(3)rsg32, rsg32" 16-Dec-15 2015_12 lethal FBgn0262986 CG43294 http://flybase.net/reports/FBgn0262986.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG43294 16-Dec-15 2015_12 FBgn0019933 S(rux)2C S(rux)2C http://flybase.net/reports/FBgn0019933.html gene 16-Dec-15 2015_12 "lethal,recessive,mitotic cell cycle defective" FBgn0065434 l(2)SH1478 lethal (2) SH1478 http://flybase.net/reports/FBgn0065434.html gene l(2)SH2 1478 16-Dec-15 2015_12 "lethal,recessive" FBgn0039246 CG10845 http://flybase.net/reports/FBgn0039246.html protein_coding_gene "0008017=microtubule binding, 0003777=microtubule motor activity, 0016887=ATPase activity, 0005524=ATP binding" 0007018=microtubule-based movement 0005871=kinesin complex "Klp96B, KIF26A/B" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001752=Kinesin motor domain" CG10845 16-Dec-15 2015_12 viable FBgn0035762 Rint1 RINT1 ortholog http://flybase.net/reports/FBgn0035762.html protein_coding_gene "0022008=neurogenesis, 0007112=male meiosis cytokinesis, 0036090=cleavage furrow ingression, 0048193=Golgi vesicle transport, 0007030=Golgi organization" "0070939=Dsl1p complex, 0005783=endoplasmic reticulum" "CG8605, rint1, Rint-1, Tip20" IPR007528=RINT-1/TIP-20 CG8605 16-Dec-15 2015_12 ENSDARG00000005547(si:dkey-202b22.4) ENSXETG00000023226(RINT1) ENSMUSG00000028999(Rint1) ENSG00000135249(RINT1) "cytokinesis defective,lethal,neuroanatomy defective,body color defective" "Golgi stackbam.THsimVP16,spermatid | third instar larval stage,Nebenkern,contractile ringbam.THsimVP16,spindlebam.THsimVP16,cleavage furrowbam.THsimVP16,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0264504 CR43903 http://flybase.net/reports/FBgn0264504.html non_protein_coding_gene CR43903 16-Dec-15 2015_12 FBgn0000763 fs(1)A543 female sterile (1) A543 http://flybase.net/reports/FBgn0000763.html gene 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive" "wing,female reproductive system" FBgn0085360 CG34331 http://flybase.net/reports/FBgn0085360.html protein_coding_gene CG34331 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0060987 l(3)S028102b lethal (3) S028102b http://flybase.net/reports/FBgn0060987.html gene 0281/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0262534 CG43088 http://flybase.net/reports/FBgn0262534.html protein_coding_gene "MB8.chrX.pasa.104-MIP02663, MB8.chrX.pasa.104" IPR027806=Harbinger transposase-derived nuclease domain CG43088 16-Dec-15 2015_12 FBgn0051545 CG31545 http://flybase.net/reports/FBgn0051545.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085714 CG41592 http://flybase.net/reports/FBgn0085714.html FBan0041592 protein_coding_gene 16-Dec-15 2015_12 FBgn0001130 Gpt Glutamate pyruvate transaminase http://flybase.net/reports/FBgn0001130.html gene GPT 16-Dec-15 2015_12 electrophoretic variant FBgn0034480 CG16898 http://flybase.net/reports/FBgn0034480.html protein_coding_gene "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG16898 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0019683 mng mango http://flybase.net/reports/FBgn0019683.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0023154 Su(mg)2-5 Suppressor of modifier of gypsy 2-5 http://flybase.net/reports/FBgn0023154.html gene 16-Dec-15 2015_12 FBgn0010557 l(2)03832a lethal (2) 03832a http://flybase.net/reports/FBgn0010557.html gene l(2)03832 16-Dec-15 2015_12 "lethal,recessive" FBgn0021988 l(2)k09624 lethal (2) k09624 http://flybase.net/reports/FBgn0021988.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0259330 C371 http://flybase.net/reports/FBgn0259330.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0260381 GSd439 http://flybase.net/reports/FBgn0260381.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0034547 CG12485 http://flybase.net/reports/FBgn0034547.html protein_coding_gene 16-Dec-15 2015_12 FBgn0044491 DTD46.6 DTD46.6 http://flybase.net/reports/FBgn0044491.html gene 16-Dec-15 2015_12 FBgn0265855 CR44644 http://flybase.net/reports/FBgn0265855.html non_protein_coding_gene CR44644 16-Dec-15 2015_12 FBgn0024305 SS3-6 Suppressor of GMR-sina 3-6 http://flybase.net/reports/FBgn0024305.html gene 0042052=rhabdomere development 16-Dec-15 2015_12 "rhabdomere,somatic clone" FBgn0265638 CR44445 http://flybase.net/reports/FBgn0265638.html non_protein_coding_gene lincRNA.264 CR44445 16-Dec-15 2015_12 FBgn0029907 Atx-1 Ataxin 1 http://flybase.net/reports/FBgn0029907.html protein_coding_gene 0003723=RNA binding "0007474=imaginal disc-derived wing vein specification, 0045494=photoreceptor cell maintenance" "CG4547, dAtx-1, ataxin-1, Atx-1, Ataxin-1, dAtx1, Ataxin1" "IPR013723=Ataxin-1/HBP1 module (AXH), IPR003652=Ataxin, AXH domain" CG4547 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective" "eye,eye photoreceptor cell,wing vein,ectopic,interommatidial bristle,ommatidium,rhabdomere of eye photoreceptor cell,heat sensitive,wing,wing margin bristle,metathoracic bristle,mesothoracic bristle" FBgn0267179 CR45619 http://flybase.net/reports/FBgn0267179.html non_protein_coding_gene CR45619 16-Dec-15 2015_12 FBgn0021949 l(2)k10411 lethal (2) k10411 http://flybase.net/reports/FBgn0021949.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001367 l(1)1Ff lethal (1) 1Ff http://flybase.net/reports/FBgn0001367.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,rescuable maternal effect" FBgn0033934 CG17385 http://flybase.net/reports/FBgn0033934.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG17385 16-Dec-15 2015_12 WBGene00012639(Y38H8A.5) "viable,visible" trichogen cell DRSC06664 EK 1.278973039 0.940801573 3.593102745 0.056067651 -0.369641076 1.562939491 FBgn0036121 CG6310 http://flybase.net/reports/FBgn0036121.html FBgn0063764 protein_coding_gene BcDNA:AT03632 CG6310 16-Dec-15 2015_12 viable FBgn0028588 l(?)AP17 lethal (?) AP17 http://flybase.net/reports/FBgn0028588.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0069936 CG41113 http://flybase.net/reports/FBgn0069936.html FBan0041113 protein_coding_gene 16-Dec-15 2015_12 FBgn0011613 l(1)I33e30 lethal (1) I33e30 http://flybase.net/reports/FBgn0011613.html FBgn0010206 gene l(1)33e30 16-Dec-15 2015_12 lethal FBgn0262567 CG43107 http://flybase.net/reports/FBgn0262567.html protein_coding_gene "lincRNA.331, MIP12466" CG43107 16-Dec-15 2015_12 FBgn0033134 Tsp42El Tetraspanin 42El http://flybase.net/reports/FBgn0033134.html FBgn0027716 protein_coding_gene 0016021=integral component of membrane "CG12840, anon-EST:Posey244, Tetraspanin at 42El, Tsp42E1, Dm.Tsp42El, tetraspanin 42E" "IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin, IPR008952=Tetraspanin, EC2 domain" CG12840 16-Dec-15 2015_12 viable FBgn0002309 l(3)84Fg lethal (3) 84Fg http://flybase.net/reports/FBgn0002309.html gene l(3)EfH2 16-Dec-15 2015_12 lethal FBgn0034361 mRpS28 mitochondrial ribosomal protein S28 http://flybase.net/reports/FBgn0034361.html FBgn0062438 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "BcDNA:RH13070, mrpS28, MRP-S35, CG5497" "IPR019375=Ribosomal protein S28, mitochondrial" CG5497 16-Dec-15 2015_12 ENSDARG00000041538(zgc:152965) WBGene00012830(Y43F8C.8) ENSMUSG00000040269(Mrps28) ENSG00000147586(MRPS28) "viable,visible" trichogen cell FBgn0261865 lgr lounger http://flybase.net/reports/FBgn0261865.html gene 0035177=larval foraging behavior 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002084 l(2)49Fm lethal (2) 49Fm http://flybase.net/reports/FBgn0002084.html gene "vr-18, l(2)vr18" 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation,dominant" FBgn0002432 l(3)KE90 lethal (3) KE90 http://flybase.net/reports/FBgn0002432.html gene 16-Dec-15 2015_12 lethal FBgn0034703 CG3045 http://flybase.net/reports/FBgn0034703.html protein_coding_gene "0009982=pseudouridine synthase activity, 0004730=pseudouridylate synthase activity, 0003723=RNA binding" 0001522=pseudouridine synthesis "IPR001406=Pseudouridine synthase I, TruA, IPR020094=Pseudouridine synthase I, TruA, N-terminal, IPR020095=Pseudouridine synthase I, TruA, C-terminal, IPR020103=Pseudouridine synthase, catalytic domain, IPR020097=Pseudouridine synthase I, TruA, alpha/beta domain" CG3045 16-Dec-15 2015_12 ENSDARG00000028976(zgc:56653) YFL001W(DEG1) WBGene00006473(tag-124) ENSXETG00000024532(pus3) ENSMUSG00000032103(Pus3) ENSG00000110060(PUS3) viable FBgn0052436 CG32436 http://flybase.net/reports/FBgn0052436.html "FBgn0037075, FBgn0037077" protein_coding_gene "HD35012, CG12973, CG6968" CG32436 16-Dec-15 2015_12 "viable,fertile,visible" "trichogen cell,supernumerary" FBgn0027164 l(2)KC-B l(2)Karp and Cherbas B http://flybase.net/reports/FBgn0027164.html gene B 16-Dec-15 2015_12 "lethal,recessive" FBgn0085778 CR40962 http://flybase.net/reports/FBgn0085778.html FBan0040962 rRNA_gene 16-Dec-15 2015_12 FBgn0003239 Rex Ribosomal exchange http://flybase.net/reports/FBgn0003239.html gene Su(Rex) 16-Dec-15 2015_12 "mitotic cell cycle defective,maternal effect,semidominant" FBgn0262067 EG7 http://flybase.net/reports/FBgn0262067.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023040 l(2)46Ec lethal (2) 46Ec http://flybase.net/reports/FBgn0023040.html FBgn0019725 gene "Complementation group G, unnamed, 5.2, l(2)46CFc, G" 16-Dec-15 2015_12 lethal FBgn0021991 l(2)k09613 lethal (2) k09613 http://flybase.net/reports/FBgn0021991.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026348 Su(dalyh)26E2 Su(dalyh)26E2 http://flybase.net/reports/FBgn0026348.html gene Su(da[lyh]) 16-Dec-15 2015_12 FBgn0267418 CR45771 http://flybase.net/reports/FBgn0267418.html pseudogene_attribute CR45771 16-Dec-15 2015_12 FBgn0262476 CG43066 http://flybase.net/reports/FBgn0262476.html "FBgn0034355, FBgn0045956, FBgn0260236" protein_coding_gene "0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity, 0005215=transporter activity" 0006836=neurotransmitter transport "0005886=plasma membrane, 0016021=integral component of membrane" "CG42510, anon-WO0149848.1, CG5226" IPR000175=Sodium:neurotransmitter symporter CG43066 16-Dec-15 2015_12 "ENSDARG00000062821(si:ch211-154h20.4),ENSDARG00000068787(si:dkey-71l10.2),ENSDARG00000007129" "ENSXETG00000002025(SLC6A17),ENSXETG00000021372(SLC6A15),ENSXETG00000023526()" "ENSMUSG00000027894(Slc6a17),ENSMUSG00000019894(Slc6a15)" "ENSG00000197106(SLC6A17),ENSG00000072041(SLC6A15)" FBgn0037535 CG14463 http://flybase.net/reports/FBgn0037535.html protein_coding_gene CG14463 16-Dec-15 2015_12 "viable,fertile" FBgn0053417 5SrRNA:CR33417 5SrRNA:CR33417 http://flybase.net/reports/FBgn0053417.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33417 CR33417 16-Dec-15 2015_12 FBgn0013667 ms(3)neo117 ms(3)neo117 http://flybase.net/reports/FBgn0013667.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0025153 ms(2)A3 ms(2)A3 http://flybase.net/reports/FBgn0025153.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0016879 l(2)39DEd lethal (2) 39DEd http://flybase.net/reports/FBgn0016879.html gene H173 16-Dec-15 2015_12 lethal FBgn0083303 E(smoDN)1644 Enhancer of smoDN 1644 http://flybase.net/reports/FBgn0083303.html gene 16-Dec-15 2015_12 FBgn0002709 mei-218 meiotic 218 http://flybase.net/reports/FBgn0002709.html "FBgn0053067, FBtr0089819, FBpp0088760, FBtr0089820, FBpp0088761, FBtr0089821, FBpp0088762" protein_coding_gene "0016321=female meiosis chromosome segregation, 0007143=female meiotic division, 0007131=reciprocal meiotic recombination" 0005737=cytoplasm "CG8923, CG33067, transcript c" CG8923 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female,fertile,female fertile,male fertile,wild-type,female semi-sterile,DNA repair defective" "cell cycle,oocyte,meiosis & nuclear chromosome | female" FBgn0036512 CG16979 http://flybase.net/reports/FBgn0036512.html protein_coding_gene "0019783=ubiquitin-like protein-specific protease activity, 0016790=thiolester hydrolase activity" 0012505=endomembrane system "IPR012462=Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2" CG16979 16-Dec-15 2015_12 ENSDARG00000056369(ufsp2) ENSMUSG00000031634(Ufsp2) ENSG00000109775(UFSP2) FBgn0002246 l(3)68Ch lethal (3) 68Ch http://flybase.net/reports/FBgn0002246.html gene "rose-gespleten region interval 7, l(3)rsg7, rsg7" 16-Dec-15 2015_12 lethal FBgn0011192 l(1)296-22 lethal (1) 296-22 http://flybase.net/reports/FBgn0011192.html FBgn0010201 gene 296-22 16-Dec-15 2015_12 "lethal,recessive" FBgn0034463 CG15125 http://flybase.net/reports/FBgn0034463.html protein_coding_gene CG15125 16-Dec-15 2015_12 viable FBgn0034566 CG9313 http://flybase.net/reports/FBgn0034566.html "FBtr0071521, FBpp0071450" protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled" "0007605=sensory perception of sound, 0007018=microtubule-based movement" "0005875=microtubule associated complex, 0005868=cytoplasmic dynein complex, 0030286=dynein complex" unnamed "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG9313 16-Dec-15 2015_12 ENSDARG00000038788(zgc:158666) ENSXETG00000020368(WDR78) ENSMUSG00000061322(Dnaic1) ENSG00000122735(DNAI1) "auditory perception defective,neurophysiology defective,viable" FBgn0011410 l(3)j8B9 lethal (3) j8B9 http://flybase.net/reports/FBgn0011410.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025723 A122 A122 http://flybase.net/reports/FBgn0025723.html gene "0007423=sensory organ development, 0007219=Notch signaling pathway" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005437 l(1)v59 lethal (1) v59 http://flybase.net/reports/FBgn0005437.html gene l(1)59 16-Dec-15 2015_12 FBgn0266684 CR45174 http://flybase.net/reports/FBgn0266684.html non_protein_coding_gene CR45174 16-Dec-15 2015_12 FBgn0038397 CG10185 http://flybase.net/reports/FBgn0038397.html protein_coding_gene "IPR019775=WD40 repeat, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR025139=Domain of unknown function DUF4062, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG10185 16-Dec-15 2015_12 WBGene00020254(T05C3.2) ENSXETG00000013507(NWD1) ENSMUSG00000048148(Nwd1) ENSG00000188039(NWD1) viable FBgn0023090 dtr defective transmitter release http://flybase.net/reports/FBgn0023090.html FBgn0051623 protein_coding_gene 0045502=dynein binding "0007268=synaptic transmission, 0044458=motile cilium assembly, 0060271=cilium morphogenesis" 0005930=axoneme "Dtr, CG31623, unnamed" "IPR001611=Leucine-rich repeat, IPR027734=Dynein assembly factor 1, axonemal" CG31623 16-Dec-15 2015_12 ENSXETG00000013785(LRRCC1) ENSG00000154099(DNAAF1) "visual behavior defective,neurophysiology defective,viable" FBgn0004782 Ccp84Ab Ccp84Ab http://flybase.net/reports/FBgn0004782.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "BG:DS00004.2, Ccp, CG1252, unnamed, cc7, cuticle cluster 7, DmelCcp84Ab" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG1252 16-Dec-15 2015_12 DRSC25096 K -0.100466093 -0.552837273 0.440149193 0.290791865 -1.529617353 -0.238832858 FBgn0261830 CG42762 http://flybase.net/reports/FBgn0261830.html protein_coding_gene CG42762 16-Dec-15 2015_12 FBgn0031969 pes peste http://flybase.net/reports/FBgn0031969.html protein_coding_gene 0005044=scavenger receptor activity "0007155=cell adhesion, 0006952=defense response" "0005887=integral component of plasma membrane, 0016020=membrane" "Peste, Pes, CG7228" IPR002159=CD36 antigen CG7228 16-Dec-15 2015_12 viable FBgn0043593 E(roDOM)2409 E(roDOM)2409 http://flybase.net/reports/FBgn0043593.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0062650 EP393 EP393 http://flybase.net/reports/FBgn0062650.html gene EP(2)0393 16-Dec-15 2015_12 FBgn0069124 mir-P323-2 mir-P323-2 http://flybase.net/reports/FBgn0069124.html miRNA_gene 16-Dec-15 2015_12 FBgn0017359 l(3)F51 lethal (3) F51 http://flybase.net/reports/FBgn0017359.html gene l(3)51 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038198 Npc2b Niemann-Pick type C-2b http://flybase.net/reports/FBgn0038198.html protein_coding_gene 0032934=sterol binding "0015918=sterol transport, 0032504=multicellular organism reproduction, 0045456=ecdysteroid biosynthetic process" 0005615=extracellular space "CT10556, NPC2, CG3153, npc2b, DmML2" "IPR014756=Immunoglobulin E-set, IPR003172=MD-2-related lipid-recognition domain" CG3153 16-Dec-15 2015_12 "viable,fertile,visible,body color defective" mesothoracic tergum FBgn0065771 l(2)SH0462 lethal (2) SH0462 http://flybase.net/reports/FBgn0065771.html gene l(2)SH2 0462 16-Dec-15 2015_12 "lethal,recessive" FBgn0004490 don-giovanni don giovanni http://flybase.net/reports/FBgn0004490.html gene "0008050=female courtship behavior, 0007621=negative regulation of female receptivity" "Don Giovanni, don Giovanni, dg" 16-Dec-15 2015_12 "courtship behavior defective,male" FBgn0024607 olfJ147 olfactory J147 http://flybase.net/reports/FBgn0024607.html gene 16-Dec-15 2015_12 smell perception defective FBgn0086384 Mer Merlin http://flybase.net/reports/FBgn0086384.html "FBgn0013951, FBgn0070004, FBgn0014341" protein_coding_gene "0005515=protein binding, 0003779=actin binding, 0008092=cytoskeletal protein binding" "0008285=negative regulation of cell proliferation, 0007291=sperm individualization, 0042981=regulation of apoptotic process, 0007476=imaginal disc-derived wing morphogenesis, 0009966=regulation of signal transduction, 0019094=pole plasm mRNA localization, 0051307=meiotic chromosome separation, 0046621=negative regulation of organ growth, 0007050=cell cycle arrest, 0042127=regulation of cell proliferation, 0007267=cell-cell signaling, 0060253=negative regulation of glial cell proliferation, 0042327=positive regulation of phosphorylation, 0072659=protein localization to plasma membrane, 0006897=endocytosis, 0009798=axis specification, 0032456=endocytic recycling, 0001751=compound eye photoreceptor cell differentiation, 0001558=regulation of cell growth, 0042048=olfactory behavior, 0008101=decapentaplegic signaling pathway, 0001934=positive regulation of protein phosphorylation, 0035329=hippo signaling, 0046669=regulation of compound eye retinal cell programmed cell death, 0007283=spermatogenesis, 0045595=regulation of cell differentiation, 0007112=male meiosis cytokinesis, 0001745=compound eye morphogenesis" "0045169=fusome, 0016324=apical plasma membrane, 0005912=adherens junction, 0016020=membrane, 0005886=plasma membrane, 0005938=cell cortex, 0016006=Nebenkern, 0005856=cytoskeleton, 0005737=cytoplasm, 0019898=extrinsic component of membrane" "CG14228, BG01543, Ezrin-moesin-radixin-2, D Merlin, Dmerlin, EMR2, merlin, Merlin, NF2, mer, D-Mer, Emr2, Merlin/Neurofibromin 2" "IPR000299=FERM domain, IPR011259=Ezrin/radixin/moesin, C-terminal, IPR029071=Ubiquitin-related domain, IPR018979=FERM, N-terminal, IPR018980=FERM, C-terminal PH-like domain, IPR008954=Moesin tail domain, IPR000798=Ezrin/radixin/moesin-like, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR011174=Ezrin/radixin/moesin, IPR019748=FERM central domain, IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR015788=Moesin/ezrin/radixin homologue 2" CG14228 16-Dec-15 2015_12 "ENSDARG00000025567(nf2b),ENSDARG00000020204(nf2a)" "ENSXETG00000016421(NF2),ENSXETG00000010090()" ENSMUSG00000009073(Nf2) ENSG00000186575(NF2) FBgn0005335 podK podoptera of Kellen Piternick http://flybase.net/reports/FBgn0005335.html gene "pod-K, podoptera of Kellen-Piternick" 16-Dec-15 2015_12 visible "wing,eye,postvertical bristle" FBgn0050342 Prp38 pre-mRNA processing factor 38 http://flybase.net/reports/FBgn0050342.html FBgn0033386 protein_coding_gene 0005515=protein binding "0000398=mRNA splicing, via spliceosome, 0010389=regulation of G2/M transition of mitotic cell cycle" "0043234=protein complex, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "CG30342, dprp38, CG8054" "IPR005037=Pre-mRNA-splicing factor 38, IPR024767=Pre-mRNA-splicing factor 38, C-terminal" CG30342 16-Dec-15 2015_12 ENSDARG00000039213(prpf38a) WBGene00008380(D1054.14) ENSXETG00000008060(prpf38a) ENSMUSG00000063800(Prpf38a) ENSG00000134748(PRPF38A) "increased cell death,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,viable,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" "wing disc,somatic clone,wing pouch" FBgn0002499 l(3)SG60 lethal (3) SG60 http://flybase.net/reports/FBgn0002499.html FBgn0004729 gene "l(3)2306, l(3)B13, l(3)ds13" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0052847 CG32847 http://flybase.net/reports/FBgn0052847.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG32847 16-Dec-15 2015_12 YER116C(SLX8) viable DRSC22901 K 0.516893721 -1.482651924 0.562264829 -0.377019019 1.572156915 0.717834331 FBgn0069145 mcl(3)Z4085 mcl(3)Z4085 http://flybase.net/reports/FBgn0069145.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0024869 l(2)k14209 lethal (2) k14209 http://flybase.net/reports/FBgn0024869.html gene 16-Dec-15 2015_12 FBgn0266197 CR44892 http://flybase.net/reports/FBgn0266197.html non_protein_coding_gene CR44892 16-Dec-15 2015_12 FBgn0033891 CG8067 http://flybase.net/reports/FBgn0033891.html protein_coding_gene 0008168=methyltransferase activity 0008152=metabolic process "IPR013216=Methyltransferase type 11, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG8067 16-Dec-15 2015_12 ENSDARG00000061629(zgc:162919) WBGene00010721(K09E4.3) ENSXETG00000008078(C20orf7) ENSMUSG00000027384(2310003L22Rik) ENSG00000101247(C20orf7) viable FBgn0263126 Ubx::Zzzz\Cs-abd-A http://flybase.net/reports/FBgn0263126.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0050284 CG30284 http://flybase.net/reports/FBgn0050284.html "FBgn0045281, FBgn0063340, FBgn0065000" protein_coding_gene "BcDNA:AT12437, NEST:bs16b04, BcDNA:AT22714" CG30284 16-Dec-15 2015_12 viable FBgn0267290 CR45726 http://flybase.net/reports/FBgn0267290.html non_protein_coding_gene CR45726 16-Dec-15 2015_12 FBgn0053322 CG33322 http://flybase.net/reports/FBgn0053322.html "FBgn0032887, FBgn0067631" protein_coding_gene "38E.23, BcDNA:AT04844, CG9329" CG33322 16-Dec-15 2015_12 "viable,fertile" FBgn0001740 l(1)HM10 lethal (1) HM10 http://flybase.net/reports/FBgn0001740.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female semi-sterile,visible,tumorigenic" "wing,adult abdomen" FBgn0037672 sage salivary gland-expressed bHLH http://flybase.net/reports/FBgn0037672.html protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007431=salivary gland development, 0006355=regulation of transcription, DNA-templated" "0005700=polytene chromosome, 0005634=nucleus" "Sage, bHLHc7, CG12952" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG12952 16-Dec-15 2015_12 "ENSXETG00000016346(TAL1),ENSXETG00000016721()" ENSG00000168874(ATOH8) embryonic stage | stage >=10 adult salivary gland primordium

increased cell death embryonic/larval salivary gland FBgn0069335 UY3164 UY3164 http://flybase.net/reports/FBgn0069335.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body & axoney-OK107" FBgn0051424 Ir94b Ionotropic receptor 94b http://flybase.net/reports/FBgn0051424.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "DmelIR94b, CG31424, IR94b, ionotropic receptor 94b" CG31424 16-Dec-15 2015_12 "body color defective,partially lethal - majority die,some die during pupal stage,auditory perception defective" mesothoracic tergum FBgn0002690 miniature-blistered miniature blistered http://flybase.net/reports/FBgn0002690.html gene mbs 16-Dec-15 2015_12 "visible,viable,poor,fertile" "wing,macrochaeta" FBgn0260860 Bet5 BET5 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0260860.html "FBgn0045026, FBgn0039753" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0016192=vesicle-mediated transport, 0006888=ER to Golgi vesicle-mediated transport" "0030008=TRAPP complex, 0005801=cis-Golgi network" "Bet5, Bet5p, CG1359, BET5" "IPR007233=Sybindin-like protein, IPR011012=Longin-like domain" CG1359 16-Dec-15 2015_12 ENSDARG00000039005(trappc1) YML077W(BET5) ENSXETG00000009070(trappc1) ENSMUSG00000049299(Trappc1) ENSG00000170043(TRAPPC1) DRSC14600 IK 1.571367212 0.524431408 1.288070269 0.323657125 0.518423784 2.670901421 FBgn0066070 Su(var)2-6 Su(var)2-6 http://flybase.net/reports/FBgn0066070.html gene 16-Dec-15 2015_12 FBgn0045960 Stalker\sORF sORF http://flybase.net/reports/FBgn0045960.html transposable_element_gene 16-Dec-15 2015_12 FBgn0265176 CR44241 http://flybase.net/reports/FBgn0265176.html FBgn0085216 non_protein_coding_gene CG34187 CR44241 16-Dec-15 2015_12 FBgn0041174 Vhl von Hippel-Lindau http://flybase.net/reports/FBgn0041174.html "FBgn0033606, FBgn0040067, FBgn0061373" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0005515=protein binding" "0006611=protein export from nucleus, 0007424=open tracheal system development, 1900037=regulation of cellular response to hypoxia, 0016567=protein ubiquitination, 0016334=establishment or maintenance of polarity of follicular epithelium, 0060438=trachea development, 0051297=centrosome organization, 0035149=lumen formation, open tracheal system, 0007026=negative regulation of microtubule depolymerization, 0090307=mitotic spindle assembly, 0007010=cytoskeleton organization, 0007427=epithelial cell migration, open tracheal system" 0030891=VCB complex "Dvhl, Von Hippel Lindau, dmVHL, vhl, von Hippel Lindau, von Hippel Lindau protein, d-vhl, BcDNA:RH61560, dVHL, DVhl, d-VHL, CG13221, VHL" "IPR022772=von Hippel-Lindau disease tumour suppressor, beta/alpha domain, IPR002714=Von Hippel-Lindau tumour suppressor protein, IPR024053=von Hippel-Lindau disease tumour suppressor, beta domain" CG13221 16-Dec-15 2015_12 ENSDARG00000070617(vhl) WBGene00006922(vhl-1) ENSXETG00000001448(VHL) "cell migration defective,lethal,viable,stress response defective,partially lethal - majority die,visible,planar polarity defective,cell polarity defective,somatic clone,recessive,non-rescuable maternal effect,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female sterile" "border follicle cell | oogenesis stage S10,border follicle cell | oogenesis stage S9,embryonic/larval trachea,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval lateral trunk,tracheal primordium,ectopic,tracheole,cell non-autonomous,presumptive embryonic/larval tracheal system,transverse connective primordium,visceral branch primordium,lateral trunk primordium,dorsal trunk primordium,trichogen cell,follicle cell,somatic clone,microtubule | somatic clone,embryonic/larval tracheal system,maternal effect,egg chamber,nurse cell,microtubulebtl.PS,heat sensitive" FBgn0265898 CR44687 http://flybase.net/reports/FBgn0265898.html non_protein_coding_gene "lincRNA.640, lincRNA.651" CR44687 16-Dec-15 2015_12 FBgn0025612 CG3062 http://flybase.net/reports/FBgn0025612.html protein_coding_gene EG:84H4.5 CG3062 16-Dec-15 2015_12 viable FBgn0028491 CG2930 http://flybase.net/reports/FBgn0028491.html "FBgn0052780, FBgn0052787" protein_coding_gene 0005427=proton-dependent oligopeptide secondary active transmembrane transporter activity 0006857=oligopeptide transport 0016020=membrane "CG32787, BcDNA:GH06717, CG32780" "IPR018456=PTR2 family proton/oligopeptide symporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR000109=Proton-dependent oligopeptide transporter family" CG2930 16-Dec-15 2015_12 "ENSDARG00000044528(slc15a1b),ENSDARG00000032010(slc15a2)" YKR093W(PTR2) "WBGene00003876(pept-2),WBGene00003877(pept-1)" ENSXETG00000012024(SLC15A2) "ENSMUSG00000022899(Slc15a2),ENSMUSG00000025557(Slc15a1)" "ENSG00000163406(SLC15A2),ENSG00000088386(SLC15A1)" viable FBgn0005635 belt belt http://flybase.net/reports/FBgn0005635.html gene 16-Dec-15 2015_12 FBgn0005356 su(msm1) suppressor of msm1 http://flybase.net/reports/FBgn0005356.html gene su(m1[5A]) 16-Dec-15 2015_12 FBgn0267666 CR46004 http://flybase.net/reports/FBgn0267666.html non_protein_coding_gene CR46004 16-Dec-15 2015_12 FBgn0060586 l(3)S093902 lethal (3) S093902 http://flybase.net/reports/FBgn0060586.html gene 0939/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0069918 CG41134 http://flybase.net/reports/FBgn0069918.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065949 l(2)SH0086 lethal (2) SH0086 http://flybase.net/reports/FBgn0065949.html gene l(2)SH2 0086 16-Dec-15 2015_12 "lethal,recessive" FBgn0016962 umpA uncoordinated with mechanoreceptor potential A http://flybase.net/reports/FBgn0016962.html gene 16-Dec-15 2015_12 FBgn0053369 5SrRNA:CR33369 5SrRNA:CR33369 http://flybase.net/reports/FBgn0053369.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33369 CR33369 16-Dec-15 2015_12 FBgn0026336 Su(tor)2-68-20 Su(tor)2-68-20 http://flybase.net/reports/FBgn0026336.html gene 16-Dec-15 2015_12 FBgn0064181 hh-CMM hh-CMM http://flybase.net/reports/FBgn0064181.html regulatory_region hh CMM 16-Dec-15 2015_12 FBgn0262759 Mst77Y-10ë¬ Male-specific pseudogene 77Y 10 http://flybase.net/reports/FBgn0262759.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0016057 prd6 prd6 http://flybase.net/reports/FBgn0016057.html gene PRD gene 6 16-Dec-15 2015_12 " oogenesis stage , embryonic stage | <8-12 hr " FBgn0026149 BCL7-like BCL7-like http://flybase.net/reports/FBgn0026149.html protein_coding_gene "CG17252, Bcl7-like" IPR006804=BCL7 CG17252 16-Dec-15 2015_12 "ENSDARG00000052907(bcl7a),ENSDARG00000026709(zgc:85678),ENSDARG00000040396(bcl7b)" WBGene00016192(C28H8.1) "ENSXETG00000003772(bcl7b),ENSXETG00000005802(BCL7B)" "ENSMUSG00000029438(Bcl7a),ENSMUSG00000029681(Bcl7b),ENSMUSG00000030814(Bcl7c)" "ENSG00000106635(BCL7B),ENSG00000099385(BCL7C),ENSG00000110987(BCL7A)" "viable,fertile,visible" mesothoracic tergum FBgn0266968 CR45419 http://flybase.net/reports/FBgn0266968.html non_protein_coding_gene CR45419 16-Dec-15 2015_12 FBgn0264373 CR43825 http://flybase.net/reports/FBgn0264373.html non_protein_coding_gene CR43825 16-Dec-15 2015_12 FBgn0060634 l(3)S085005b lethal (3) S085005b http://flybase.net/reports/FBgn0060634.html gene 0850/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0001900 l(2)22Aa lethal (2) 22Aa http://flybase.net/reports/FBgn0001900.html gene "l(2)neh-14, l(2)neh14" 16-Dec-15 2015_12 lethal FBgn0024433 Dl-l Delta-like http://flybase.net/reports/FBgn0024433.html gene "0007506=gonadal mesoderm development, 0008354=germ cell migration" Deltalike1 16-Dec-15 2015_12 embryo FBgn0053489 CG33489 http://flybase.net/reports/FBgn0053489.html FBgn0036174 protein_coding_gene CG6110 CG33489 16-Dec-15 2015_12 ENSMUSG00000023931(Efhb) ENSG00000163576(EFHB) "viable,fertile" FBgn0030025 CG2147 http://flybase.net/reports/FBgn0030025.html FBgn0064918 protein_coding_gene BcDNA:LP02728 CG2147 16-Dec-15 2015_12 FBgn0030836 CG8664 http://flybase.net/reports/FBgn0030836.html protein_coding_gene CG8664 16-Dec-15 2015_12 viable FBgn0014910 anon-4Fd anon-4Fd http://flybase.net/reports/FBgn0014910.html gene 16-Dec-15 2015_12 FBgn0027885 Aac11 Aac11 http://flybase.net/reports/FBgn0027885.html FBgn0022116 protein_coding_gene 0005515=protein binding "0022008=neurogenesis, 0043066=negative regulation of apoptotic process" 0005634=nucleus "antiapoptosis clone-11, BcDNA:LD09852, Api5, l(2)k06710, apoptosis inhibitor-5, BcDNA.LD09852, antiapoptosis clone 11, CG6582, AAC-11" "IPR008383=Apoptosis inhibitory 5, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG6582 16-Dec-15 2015_12 ENSDARG00000033597(api5) ENSXETG00000022227(API5) ENSMUSG00000027193(Api5) ENSG00000166181(API5) "lethal,recessive,visible,neuroanatomy defective" "wing blade,embryonic/larval neuroblast,ganglion mother cell" FBgn0265219 shf::Hsap\WIF1 http://flybase.net/reports/FBgn0265219.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0034046 tun tungus http://flybase.net/reports/FBgn0034046.html FBgn0046770 protein_coding_gene "0016811=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" "0007611=learning or memory, 0008355=olfactory learning" "CG8253, BcDNA:LD38553, Ntaq1" "IPR023128=Protein N-terminal glutamine amidohydrolase, alpha beta roll" CG8253 16-Dec-15 2015_12 ENSDARG00000070403(si:rp71-45k5.3) WBGene00011065(R06C7.6) ENSMUSG00000022359(Wdyhv1) ENSG00000156795(WDYHV1) "viable,memory defective" FBgn0036273 CG10426 http://flybase.net/reports/FBgn0036273.html protein_coding_gene "0046030=inositol trisphosphate phosphatase activity, 0004439=phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity" "0046856=phosphatidylinositol dephosphorylation, 0016311=dephosphorylation" "0005737=cytoplasm, 0016020=membrane" "pharbin-like, INPPE5, IPP" "IPR005135=Endonuclease/exonuclease/phosphatase, IPR000300=Inositol polyphosphate-related phosphatase" CG10426 16-Dec-15 2015_12 "ENSXETG00000000753(INPP5E),ENSXETG00000027618(),ENSXETG00000025944(),ENSXETG00000025495(),ENSXETG00000010591(),ENSXETG00000024530(),ENSXETG00000009758(),ENSXETG00000011525(),ENSXETG00000025406()" ENSMUSG00000026925(Inpp5e) ENSG00000148384(INPP5E) "neuroanatomy defective,viable" "anterior fascicle & synapse,synapse,intersegmental nerve" FBgn0025002 E(var)70-2 E(var)70-2 http://flybase.net/reports/FBgn0025002.html gene 16-Dec-15 2015_12 FBgn0065230 l(2)SH2183 lethal (2) SH2183 http://flybase.net/reports/FBgn0065230.html gene l(2)SH2 2183 16-Dec-15 2015_12 "lethal,recessive" FBgn0002795 ms(1)3 male sterile (1) 3 http://flybase.net/reports/FBgn0002795.html gene 16-Dec-15 2015_12 "male sterile,female fertile" FBgn0085683 CG41552 http://flybase.net/reports/FBgn0085683.html FBan0041552 protein_coding_gene 16-Dec-15 2015_12 FBgn0031770 CG13995 http://flybase.net/reports/FBgn0031770.html "FBgn0046571, FBgn0046573" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.170, anon-WO0170980.169" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG13995 16-Dec-15 2015_12 viable FBgn0038515 CG5823 http://flybase.net/reports/FBgn0038515.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0030433=ER-associated ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination" 0005789=endoplasmic reticulum membrane "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG5823 16-Dec-15 2015_12 ENSDARG00000061161(zgc:162164) YER100W(UBC6) WBGene00022450(ubc-26) ENSXETG00000001033(ube2j2) "ENSMUSG00000023286(Ube2j2),ENSMUSG00000058581" ENSG00000160087(UBE2J2) "viable,fertile" FBgn0001663 l(1)E34 lethal (1) E34 http://flybase.net/reports/FBgn0001663.html gene l(1)E34[ts] 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" FBgn0051664 CG31664 http://flybase.net/reports/FBgn0051664.html FBgn0031366 protein_coding_gene CG15622 CG31664 16-Dec-15 2015_12 viable FBgn0069161 mcl(3)Z1956 mcl(3)Z1956 http://flybase.net/reports/FBgn0069161.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0085223 CG34194 http://flybase.net/reports/FBgn0085223.html protein_coding_gene IPR024512=Small subunit of serine palmitoyltransferase-like CG34194 16-Dec-15 2015_12 "ENSDARG00000041778(zgc:136867),ENSDARG00000071203(zgc:112487)" "ENSMUSG00000043461(1110032A04Rik),ENSMUSG00000044408(1110002B05Rik)" FBgn0267326 Ntl Neurotransmitter transporter-like http://flybase.net/reports/FBgn0267326.html "FBgn0031934, FBgn0004582" protein_coding_gene "0015193=L-proline transmembrane transporter activity, 0015187=glycine transmembrane transporter activity, 0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity" "0007287=Nebenkern assembly, 1903346=positive regulation of protein polyglycylation, 0015824=proline transport, 0006836=neurotransmitter transport, 0030317=sperm motility, 0036233=glycine import, 0007291=sperm individualization" "0016020=membrane, 0016021=integral component of membrane, 0005634=nucleus, 0016007=mitochondrial derivative, 0005739=mitochondrion, 0016006=Nebenkern" "ntl, Mp, CG7075, Membrane protein" IPR000175=Sodium:neurotransmitter symporter CG7075 16-Dec-15 2015_12 FBgn0060664 l(3)S080906 lethal (3) S080906 http://flybase.net/reports/FBgn0060664.html gene 0809/06 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260659 CG42542 http://flybase.net/reports/FBgn0260659.html "FBgn0051303, FBgn0038297" protein_coding_gene 0016020=membrane "CG31303, CG4196" IPR001727=Uncharacterised protein family UPF0016 CG42542 16-Dec-15 2015_12 ENSDARG00000034600(tmem165) YBR187W(GDT1) WBGene00021847(Y54F10AL.1) ENSMUSG00000029234(Tmem165) ENSG00000134851(TMEM165) DRSC22264 I 1.116935161 2.92967633 0.981846972 1.068903056 0.844129052 -0.365539976 FBgn0265890 CR44679 http://flybase.net/reports/FBgn0265890.html non_protein_coding_gene lincRNA.630 CR44679 16-Dec-15 2015_12 FBgn0029061 l(1)G0372 lethal (1) G0372 http://flybase.net/reports/FBgn0029061.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025732 sca::Hsap\FGG sca::Hsap\FGG http://flybase.net/reports/FBgn0025732.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0025563 anon-23Cc anon-23Cc http://flybase.net/reports/FBgn0025563.html gene c2.5 16-Dec-15 2015_12 FBgn0025764 l(3)89Df lethal (3) 89Df http://flybase.net/reports/FBgn0025764.html gene l(3)M2922 16-Dec-15 2015_12 "lethal,recessive" FBgn0022261 l(2)k00705 lethal (2) k00705 http://flybase.net/reports/FBgn0022261.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069312 X-206-23 X-206-23 http://flybase.net/reports/FBgn0069312.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0036689 CG7730 http://flybase.net/reports/FBgn0036689.html protein_coding_gene CG7730 16-Dec-15 2015_12 viable FBgn0025634 CG13367 http://flybase.net/reports/FBgn0025634.html FBgn0013389 protein_coding_gene "anon-1BCb, EG:115C2.8" CG13367 16-Dec-15 2015_12 ENSXETG00000018528(GATAD1) ENSMUSG00000007415 ENSG00000157259(GATAD1) " adult stage , embryonic stage " viable FBgn0263874 CR43721 http://flybase.net/reports/FBgn0263874.html non_protein_coding_gene CG43268 CR43721 16-Dec-15 2015_12 FBgn0053349 ppk25 pickpocket 25 http://flybase.net/reports/FBgn0053349.html FBgn0033120 protein_coding_gene "0005515=protein binding, 0005272=sodium channel activity" "0019236=response to pheromone, 0008049=male courtship behavior, 0006814=sodium ion transport" "0043234=protein complex, 0016021=integral component of membrane" "llz, CG15242, lounge lizard, CG33349" "IPR001873=Na+ channel, amiloride-sensitive" CG33349 16-Dec-15 2015_12 "courtship behavior defective,male,heat sensitive,viable,lethal" FBgn0002437 l(3)L6B lethal (3) L6B http://flybase.net/reports/FBgn0002437.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069983 BG02330 BG02330 http://flybase.net/reports/FBgn0069983.html gene 16-Dec-15 2015_12 stress response defective FBgn0044809 TotZ Turandot Z http://flybase.net/reports/FBgn0044809.html FBgn0051507 protein_coding_gene "0034599=cellular response to oxidative stress, 0009617=response to bacterium, 0034605=cellular response to heat, 0034644=cellular response to UV" "0005615=extracellular space, 0005576=extracellular region" "tot, CG31507, Totz" IPR010825=Stress-inducible humoral factor Turandot CG31507 16-Dec-15 2015_12 FBgn0028974 xmas-2 xmas-2 http://flybase.net/reports/FBgn0028974.html "FBgn0030822, FBgn0052562" protein_coding_gene "0003676=nucleic acid binding, 0005515=protein binding, 0000166=nucleotide binding" "0016973=poly(A)+ mRNA export from nucleus, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005643=nuclear pore "CG32562, Xmas-2, CG8919, X-linked male sterile 2" "IPR005062=SAC3/GANP/THP3, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG32562 16-Dec-15 2015_12 ENSDARG00000021402(mcm3ap) WBGene00017642(F20D12.2) ENSG00000160294(MCM3AP) "viable,visible" trichogen cell FBgn0000931 fs(2)A1 female sterile (2) A1 http://flybase.net/reports/FBgn0000931.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0042174 CR18854 http://flybase.net/reports/FBgn0042174.html FBgn0032148 pseudogene_attribute "0003727=single-stranded RNA binding, 0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" "0006417=regulation of translation, 0055114=oxidation-reduction process" "CG13122, CG18854, 1D-myo-Inositol-trisphosphate-3-kinase" "IPR004088=K Homology domain, type 1, IPR031119=STAR-domain RNA-binding protein GLD-1/HOW, IPR005123=Oxoglutarate/iron-dependent dioxygenase" CR18854 16-Dec-15 2015_12 embryonic/larval hemocyte | third instar larval stage DRSC02702 IE 1.646486754 1.234347995 -1.518121469 -0.008514232 1.11953391 -1.131198916 FBgn0030435 CG4645 http://flybase.net/reports/FBgn0030435.html protein_coding_gene 0016020=membrane IPR006977=Yip1 domain CG4645 16-Dec-15 2015_12 "ENSDARG00000021399(yipf2),ENSDARG00000014474(yipf1)" YGL161C(YIP5) WBGene00021294(Y25C1A.7) "ENSXETG00000019983(YIPF1),ENSXETG00000009356(TGas103f06.1)" "ENSMUSG00000057375(Yipf1),ENSMUSG00000032182(Yipf2)" "ENSG00000058799(YIPF1),ENSG00000130733(YIPF2)" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0052829 CG32829 http://flybase.net/reports/FBgn0052829.html protein_coding_gene CG32829 16-Dec-15 2015_12 viable DRSC22805 IE 3.24409376 1.07349094 5.831226194 1.028555556 -0.334364748 1.193639713 FBgn0011858 tRNA:F2:89BC transfer RNA:phe2:89BC http://flybase.net/reports/FBgn0011858.html "FBgn0011856, FBgn0051586, FBgn0060232" tRNA_gene "0033402=UUC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:phe2:89BC, tRNA:F:GAA:AE002708-b, CR31586, chr3R.trna12-PheGAA, phe-tRNA-2, tRNA-Phe-2, AE002708.trna6-PheGAA" CR31586 16-Dec-15 2015_12 FBgn0041584 whsc1 whsc1 http://flybase.net/reports/FBgn0041584.html gene Dm_whsc1 16-Dec-15 2015_12 FBgn0260017 troya troya http://flybase.net/reports/FBgn0260017.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0267059 CR45503 http://flybase.net/reports/FBgn0267059.html non_protein_coding_gene Dm_X:95517 CR45503 16-Dec-15 2015_12 FBgn0027969 l(3)S144405 lethal (3) S144405 http://flybase.net/reports/FBgn0027969.html gene 1444/05 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0010492 l(2)01482 lethal (2) 01482 http://flybase.net/reports/FBgn0010492.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal,recessive,partially,rescuable maternal effect,partially lethal - majority die" "embryonic/first instar larval cuticle,head,abdomen,posterior" FBgn0011380 l(3)j5B6 lethal (3) j5B6 http://flybase.net/reports/FBgn0011380.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053140 CG33140 http://flybase.net/reports/FBgn0053140.html "FBgn0033150, FBgn0065001" protein_coding_gene "CG11074, BcDNA:AT21895" CG33140 16-Dec-15 2015_12 ENSMUSG00000039110(Mycbpap) viable FBgn0014465 Cp7Fb Chorion protein b at 7F http://flybase.net/reports/FBgn0014465.html FBgn0030044 protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion "B, C, CG15350, cp7Fb" CG15350 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage S10B-13 , oogenesis stage | stage S10-12 " follicle cell

FBgn0014094 anon-3Aa anon-3Aa http://flybase.net/reports/FBgn0014094.html gene 16-Dec-15 2015_12 " embryonic stage , adult stage " FBgn0264700 CR43969 http://flybase.net/reports/FBgn0264700.html non_protein_coding_gene CR43969 16-Dec-15 2015_12 FBgn0052643 CG32643 http://flybase.net/reports/FBgn0052643.html FBgn0045364 protein_coding_gene NEST:bs08h10 CG32643 16-Dec-15 2015_12 viable FBgn0060335 l(3)S144608 lethal (3) S144608 http://flybase.net/reports/FBgn0060335.html gene 1446/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0023473 anon-30Fa anon-30Fa http://flybase.net/reports/FBgn0023473.html gene 16-Dec-15 2015_12 FBgn0061073 l(3)S016704b lethal (3) S016704b http://flybase.net/reports/FBgn0061073.html gene 0167/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0022725 p22 p22 http://flybase.net/reports/FBgn0022725.html gene 16-Dec-15 2015_12 FBgn0000708 fltN flight defective N http://flybase.net/reports/FBgn0000708.html gene 16-Dec-15 2015_12 flight defective FBgn0004801 fs(2)ltoRG3 female sterile (2) ltoRG3 http://flybase.net/reports/FBgn0004801.html gene "0048477=oogenesis, 0007297=ovarian follicle cell migration" 16-Dec-15 2015_12 female sterile FBgn0266671 Sec6 Sec6 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266671.html "FBgn0266611, FBgn0034367" protein_coding_gene 0000149=SNARE binding "0072659=protein localization to plasma membrane, 0016192=vesicle-mediated transport, 0045313=rhabdomere membrane biogenesis, 0043001=Golgi to plasma membrane protein transport, 0007009=plasma membrane organization, 0016080=synaptic vesicle targeting, 0007298=border follicle cell migration, 0006887=exocytosis, 0016081=synaptic vesicle docking, 0032456=endocytic recycling, 0072697=protein localization to cell cortex, 0007269=neurotransmitter secretion" "0005915=zonula adherens, 0005737=cytoplasm, 0000145=exocyst, 0016028=rhabdomere, 0016020=membrane" "Sec6p, dsec6, sec 6, sec6, CG5341, Dsec6" IPR010326=Exocyst complex component Sec6 CG5341 16-Dec-15 2015_12 ENSDARG00000014582(sec6l1) YIL068C(SEC6) WBGene00017284(sec-6) ENSXETG00000006195(Q6DJR6_XENTR) ENSMUSG00000034152(Exoc3) ENSG00000180104(EXOC3) DRSC06932 EK -0.322984004 -0.482431596 -2.177827747 1.107653421 -0.082435357 2.222515112 FBgn0002123 l(2)hst lethal (2) histolytic http://flybase.net/reports/FBgn0002123.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0265471 CR44364 http://flybase.net/reports/FBgn0265471.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0264828 CR44036 http://flybase.net/reports/FBgn0264828.html non_protein_coding_gene CR44036 16-Dec-15 2015_12 FBgn0262462 mir-iab-4 mir-iab-4 stem loop http://flybase.net/reports/FBgn0262462.html "FBgn0082170, FBgn0067677, FBgn0082171, FBgn0262336" miRNA_gene "miR-iab4, miR-iab-4-5p, iab-4 microRNA, iab-4-5p, iab-4-3p, mir-iab4, mir-iab-4-5p, CR33624, miR-iab-4, mir-iab-4-3p, miR-iab-4-3p, MIR-iab-4, iab-4, dme-iab-4, CR33623, CR43043" CR43043 16-Dec-15 2015_12 "visible,lethal,homeotic" "haltere,wing,wing margin" FBgn0013508 l(1)U3 lethal (1) U3 http://flybase.net/reports/FBgn0013508.html gene U-3 16-Dec-15 2015_12 "lethal,recessive" FBgn0264440 CR43858 http://flybase.net/reports/FBgn0264440.html non_protein_coding_gene CR43858 16-Dec-15 2015_12 FBgn0027194 l(2)51Fb lethal (2) 51Fb http://flybase.net/reports/FBgn0027194.html gene unnamed 16-Dec-15 2015_12 "male sterile,recessive,lethal" FBgn0013702 mt:tRNA:P mitochondrial proline tRNA http://flybase.net/reports/FBgn0013702.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "CR34088, mtdbD00006310" CR34088 16-Dec-15 2015_12 FBgn0086400 BG02439 http://flybase.net/reports/FBgn0086400.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective,sleep defective" FBgn0033475 CG12129 http://flybase.net/reports/FBgn0033475.html protein_coding_gene 0003723=RNA binding cg12129 "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1, IPR009097=RNA ligase/cyclic nucleotide phosphodiesterase, IPR019510=Protein kinase A anchor protein, nuclear localisation signal domain" CG12129 16-Dec-15 2015_12 WBGene00016019(C23H3.3) ENSXETG00000006149(ASCC1) ENSMUSG00000044475(Ascc1) ENSG00000138303(ASCC1) viable FBgn0082346 HM431 HM431 http://flybase.net/reports/FBgn0082346.html gene 16-Dec-15 2015_12 FBgn0036236 CG6931 http://flybase.net/reports/FBgn0036236.html protein_coding_gene IPR018958=SMI1/KNR4-like domain CG6931 16-Dec-15 2015_12 ENSDARG00000011926(zgc:91821) ENSXETG00000002149(C18orf10) ENSMUSG00000024269(5730494M16Rik) ENSG00000134779(C18orf10) viable FBgn0050285 CG30285 http://flybase.net/reports/FBgn0050285.html protein_coding_gene CG30285 16-Dec-15 2015_12 viable FBgn0065567 l(2)SH0977 lethal (2) SH0977 http://flybase.net/reports/FBgn0065567.html gene l(2)SH2 0977 16-Dec-15 2015_12 "lethal,recessive" FBgn0065291 l(2)SH2011 lethal (2) SH2011 http://flybase.net/reports/FBgn0065291.html gene l(2)SH2 2011 16-Dec-15 2015_12 "lethal,recessive" FBgn0267446 Su(Ste):CR45796 Supressor of Stellate:CR45796 http://flybase.net/reports/FBgn0267446.html non_protein_coding_gene CR45796 CR45796 16-Dec-15 2015_12 FBgn0267001 Ten-a Tenascin accessory http://flybase.net/reports/FBgn0267001.html "FBgn0000266, FBgn0259240, FBgn0004446, FBgn0026800, FBgn0026801, FBgn0030381, FBgn0030382, FBgn0030383, FBgn0030379, FBgn0030378" protein_coding_gene 0003824=catalytic activity "0008039=synaptic target recognition, 0097264=self proteolysis, 0051124=synaptic growth at neuromuscular junction, 0016200=synaptic target attraction, 0007155=cell adhesion, 0007160=cell-matrix adhesion, 0048036=central complex development" "0005576=extracellular region, 0042734=presynaptic membrane, 0031594=neuromuscular junction, 0005578=proteinaceous extracellular matrix, 0005886=plasma membrane" "Ten[a], CG15733, tenA, ten[a], central body defect, Ten11A, ten-a, CG2578, CG42338, DmtenA, cbd, CG2590, CG12720, CG18182, 1.2, Dmtena, CG11270, CG32659, unnamed, tenA(AT)[[14]], Teneurin, tenascin-like molecule accessory" "IPR006530=YD repeat, IPR013111=EGF-like domain, extracellular, IPR013032=EGF-like, conserved site, IPR011042=Six-bladed beta-propeller, TolB-like, IPR028916=Tox-GHH domain, IPR000742=EGF-like domain, IPR011041=Soluble quinoprotein glucose/sorbosone dehydrogenase, IPR022385=Rhs repeat-associated core" CG42338 16-Dec-15 2015_12 "ENSDARG00000005479(odz3),ENSDARG00000034264(odz4),ENSDARG00000007627,ENSDARG00000037122(LOC563197),ENSDARG00000011171,ENSDARG00000003403(LOC563094)" WBGene00006498(ten-1) "ENSXETG00000016434(ODZ2),ENSXETG00000015288(ODZ4)" "ENSMUSG00000049336(Odz2),ENSMUSG00000031561(Odz3),ENSMUSG00000048078(Odz4),ENSMUSG00000016150(Odz1)" "ENSG00000145934(ODZ2),ENSG00000218336(ODZ3),ENSG00000149256(ODZ4),ENSG00000009694(ODZ1)" FBgn0051609 CG31609 http://flybase.net/reports/FBgn0051609.html FBgn0043538 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005576=extracellular region "unnamed, anon-AE003623.1" "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG31609 16-Dec-15 2015_12 ENSDARG00000069736 viable FBgn0265048 cv-d crossveinless d http://flybase.net/reports/FBgn0265048.html "FBgn0000398, FBgn0051150, FBgn0038372, FBgn0038374, FBgn0038375" protein_coding_gene "0043395=heparan sulfate proteoglycan binding, 0036122=BMP binding, 0015026=coreceptor activity, 0005319=lipid transporter activity" "0007474=imaginal disc-derived wing vein specification, 0006869=lipid transport, 0030513=positive regulation of BMP signaling pathway" 0005615=extracellular space "CG9625, CG9627, CG9622, Cv-d, CG31150" "IPR015819=Lipid transport protein, beta-sheet shell, IPR001747=Lipid transport protein, N-terminal, IPR015255=Vitellinogen, open beta-sheet, IPR001846=von Willebrand factor, type D domain, IPR015816=Vitellinogen, beta-sheet N-terminal, IPR011030=Vitellinogen, superhelical" CG31150 16-Dec-15 2015_12 "ENSDARG00000016825(vtg6),ENSDARG00000055842(zgc:136383),ENSDARG00000041774,ENSDARG00000033770(vtg1),ENSDARG00000055818,ENSDARG00000055809(vtg2),ENSDARG00000055910(LOC560066),ENSDARG00000016448(vtg3)" "WBGene00006925(vit-1),WBGene00006929(vit-5),WBGene00006928(vit-4),WBGene00006927(vit-3),WBGene00006926(vit-2),WBGene00006930(vit-6)" "viable,fertile,visible,recessive" "posterior crossvein,wing margin,anterior crossvein" FBgn0013590 l(3)97Df lethal (3) 97Df http://flybase.net/reports/FBgn0013590.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0067869 Mod(Prat:bw)3-6 Mod(Prat:bw)3-6 http://flybase.net/reports/FBgn0067869.html gene Mod-3-6 16-Dec-15 2015_12 viable FBgn0061109 l(3)S007359 lethal (3) S007359 http://flybase.net/reports/FBgn0061109.html gene 0073/59 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033351 CG8235 http://flybase.net/reports/FBgn0033351.html protein_coding_gene 0000049=tRNA binding 0017101=aminoacyl-tRNA synthetase multienzyme complex "IPR012340=Nucleic acid-binding, OB-fold, IPR002547=tRNA-binding domain" CG8235 16-Dec-15 2015_12 ENSDARG00000060036(aimp1) YGL105W(ARC1) ENSXETG00000019862(scye1) ENSMUSG00000028029(Aimp1) ENSG00000164022(AIMP1) FBgn0000818 fs(1)K811 female sterile (1) K811 http://flybase.net/reports/FBgn0000818.html gene 16-Dec-15 2015_12 "female sterile,recessive" dorsal appendage FBgn0010306 mod(r)1 modulator of rudimentary 1 http://flybase.net/reports/FBgn0010306.html gene 16-Dec-15 2015_12 FBgn0037836 CG14692 http://flybase.net/reports/FBgn0037836.html protein_coding_gene 0032027=myosin light chain binding "IPR003117=cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, IPR000048=IQ motif, EF-hand binding site" CG14692 16-Dec-15 2015_12 viable FBgn0085601 CG41287 http://flybase.net/reports/FBgn0085601.html FBan0041287 protein_coding_gene 16-Dec-15 2015_12 FBgn0052855 CG32855 http://flybase.net/reports/FBgn0052855.html protein_coding_gene unnamed CG32855 16-Dec-15 2015_12 viable FBgn0259643 B0915 http://flybase.net/reports/FBgn0259643.html gene 16-Dec-15 2015_12 visible "wing vein L3,wing" FBgn0069434 Egfr::Tl Egfr::Tl http://flybase.net/reports/FBgn0069434.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0266692 CR45182 http://flybase.net/reports/FBgn0266692.html non_protein_coding_gene CR45182 16-Dec-15 2015_12 FBgn0036258 CG5642 http://flybase.net/reports/FBgn0036258.html protein_coding_gene 0003743=translation initiation factor activity "0006413=translational initiation, 0048812=neuron projection morphogenesis" "0005852=eukaryotic translation initiation factor 3 complex, 0005829=cytosol" eIF3l IPR019382=Translation initiation factor 3 complex subunit L CG5642 16-Dec-15 2015_12 ENSDARG00000006729(eif3s6ip) WBGene00015920(C17G10.9) ENSXETG00000027274(eif3s6ip) ENSMUSG00000033047(Eif3l) ENSG00000100129(EIF3L) viable DRSC10530 E -1.060752081 1.141647826 -1.868770931 0.12586034 0.128721837 0.798260958 FBgn0000162 baton baton http://flybase.net/reports/FBgn0000162.html gene 16-Dec-15 2015_12 "partially lethal - majority die,visible,semidominant" "eye,tergite" FBgn0053247 Ste:CG33247 Ste:CG33247 http://flybase.net/reports/FBgn0053247.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33247" "IPR000704=Casein kinase II, regulatory subunit, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG33247 16-Dec-15 2015_12 FBgn0038568 CG14315 http://flybase.net/reports/FBgn0038568.html protein_coding_gene CG14315 16-Dec-15 2015_12 viable FBgn0085771 28SrRNA-ë¬:CR40741 28S ribosomal RNA pseudogene:CR40741 http://flybase.net/reports/FBgn0085771.html FBan0040741 pseudogene_attribute CR40741 CR40741 16-Dec-15 2015_12 FBgn0002351 l(3)87Dc lethal (3) 87Dc http://flybase.net/reports/FBgn0002351.html gene "C1, l(3)B-103, l(3)B103, B-103, B103" 16-Dec-15 2015_12 lethal FBgn0030569 CG9411 http://flybase.net/reports/FBgn0030569.html protein_coding_gene CG9411 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265820 CR44609 http://flybase.net/reports/FBgn0265820.html non_protein_coding_gene lincRNA.41 CR44609 16-Dec-15 2015_12 FBgn0061510 fsl fusolo http://flybase.net/reports/FBgn0061510.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "viable,sterile" "meiosis & nuclear chromosome,anaphase & condensed nuclear chromosomeBK10),telophase & nuclear chromosomeBK10),nuclear chromosomeBK10),nuclear chromosome,kinetochore,microtubule" FBgn0085529 CG40867 http://flybase.net/reports/FBgn0085529.html FBan0040867 protein_coding_gene 16-Dec-15 2015_12 FBgn0034879 Rrp4 Rrp4 http://flybase.net/reports/FBgn0034879.html protein_coding_gene "0000175=3'-5'-exoribonuclease activity, 0003723=RNA binding" "0010468=regulation of gene expression, 0006397=mRNA processing" "0000176=nuclear exosome (RNase complex), 0000177=cytoplasmic exosome (RNase complex), 0005737=cytoplasm, 0005652=nuclear lamina" "rrp4, CG3931, dRrp4, RRP4" "IPR026699=Exosome complex RNA-binding protein 1/RRP40/RRP4, IPR022967=RNA-binding domain, S1, IPR012340=Nucleic acid-binding, OB-fold, IPR004088=K Homology domain, type 1, IPR025721=Exosome complex component, N-terminal domain" CG3931 16-Dec-15 2015_12 ENSDARG00000028688(exosc2) YHR069C(RRP4) WBGene00022232(exos-2) ENSXETG00000001340(Q5BJ85_XENTR) ENSMUSG00000039356(Exosc2) ENSG00000130713(EXOSC2) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266245 CR44940 http://flybase.net/reports/FBgn0266245.html non_protein_coding_gene lincRNA.747 CR44940 16-Dec-15 2015_12 FBgn0062569 Mod(var)E1672 Mod(var)E1672 http://flybase.net/reports/FBgn0062569.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" E1672 16-Dec-15 2015_12 "partially lethal - majority die,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002907 mus310 mutagen-sensitive 310 http://flybase.net/reports/FBgn0002907.html gene mus(3)310 16-Dec-15 2015_12 "DNA repair defective,radiation sensitive,chemical sensitive,recessive" FBgn0026417 Hus1-like Hus1-like http://flybase.net/reports/FBgn0026417.html protein_coding_gene "0006281=DNA repair, 0044773=mitotic DNA damage checkpoint, 0044778=meiotic DNA integrity checkpoint, 0035038=female pronucleus assembly" "0030896=checkpoint clamp complex, 0005737=cytoplasm, 0005730=nucleolus" "CG2525, hus1, Hus-1, DmHus1, Hus1" "IPR007150=Checkpoint protein Hus1/Mec3, IPR016580=Cell cycle checkpoint, Hus1" CG2525 16-Dec-15 2015_12 ENSDARG00000061380(zgc:162895) WBGene00002042(hus-1) ENSXETG00000015679(Q6DF51_XENTR) "ENSMUSG00000020413(Hus1),ENSMUSG00000076430(Hus1b)" "ENSG00000136273(HUS1),ENSG00000188996(HUS1B)" "viable,fertile,female sterile,radiation resistant,chemical sensitive,planar polarity defective" "wing,posterior compartment,nucleus110),egg,nucleus,oocyte" FBgn0040797 CG13066 http://flybase.net/reports/FBgn0040797.html protein_coding_gene CG13066 16-Dec-15 2015_12 viable FBgn0260781 10-Feb http://flybase.net/reports/FBgn0260781.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0001224 Hsp23 Heat shock protein 23 http://flybase.net/reports/FBgn0001224.html protein_coding_gene "0005515=protein binding, 0003779=actin binding" "0009631=cold acclimation, 0009408=response to heat, 0001666=response to hypoxia" 0005875=microtubule associated complex "DmHsp23, 23, HSP23/IAP, small hsp locus 67B, Hsp-23, hsp 23, hsp 23K, hsp23/22, hsp23, heat-shock protein 23, CG4463, hsp 22K, Protein 23, DmHSP23, Hsp 23, HSP23" "IPR002068=Alpha crystallin/Hsp20 domain, IPR031107=Small heat shock protein HSP20, IPR008978=HSP20-like chaperone, IPR001436=Alpha crystallin/Heat shock protein" CG4463 16-Dec-15 2015_12 "ENSDARG00000041065(hspb1),ENSDARG00000058362(LOC100331249),ENSDARG00000052447(cryabb),ENSDARG00000058365(hspb8)" "WBGene00004798(sip-1),WBGene00002020(hsp-16.49),WBGene00002015(hsp-16.1),WBGene00002018(hsp-16.41),WBGene00002016(hsp-16.2),WBGene00008592(F08H9.4)" " larval stage | first instar , larval stage , pupal stage | early , prepupal stage , embryonic stage | early " organism

" larval stage | third instar , pupal stage , embryonic stage " "viable,cold stress response defective" "embryonic/larval heart | P-stage,mitochondrion | P-stage,sarcomere | P-stage" FBgn0043476 l(3)66EFj lethal (3) 66EFj http://flybase.net/reports/FBgn0043476.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014469 Cyp4e2 Cytochrome P450-4e2 http://flybase.net/reports/FBgn0014469.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle, 0012505=endomembrane system" "P450, CyP4e2, Cyp4E2, 4e2, cytochrome P450, CG2060, P-450, Cyt-P450-4E2, CYP4E2" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG2060 16-Dec-15 2015_12 YMR015C(ERG5) "viable,fertile,partially lethal - majority die,some die during pupal stage,lethal" FBgn0069211 hyp-Xh hyp-Xh http://flybase.net/reports/FBgn0069211.html gene hyp[Xh] 16-Dec-15 2015_12 FBgn0039849 CG11334 http://flybase.net/reports/FBgn0039849.html protein_coding_gene "0045182=translation regulator activity, 0046523=S-methyl-5-thioribose-1-phosphate isomerase activity" "0035220=wing disc development, 0019509=L-methionine biosynthetic process from methylthioadenosine, 0006412=translation" "0005851=eukaryotic translation initiation factor 2B complex, 0005737=cytoplasm" "IPR000649=Initiation factor 2B-related, IPR005251=Methylthioribose-1-phosphate isomerase, IPR027363=Methylthioribose-1-phosphate isomerase-like, N-terminal domain, IPR011559=Initiation factor 2B alpha/beta/delta" CG11334 16-Dec-15 2015_12 YPR118W(MRI1) WBGene00007236(C01G10.9) ENSXETG00000021867(TGas129a07.1) ENSMUSG00000004996(Mri1) ENSG00000037757(MRI1) viable FBgn0266879 CR45340 http://flybase.net/reports/FBgn0266879.html non_protein_coding_gene CR45340 16-Dec-15 2015_12 FBgn0039266 CG11791 http://flybase.net/reports/FBgn0039266.html protein_coding_gene CG11791 16-Dec-15 2015_12 viable FBgn0032034 Rcd4 Reduction in Cnn dots 4 http://flybase.net/reports/FBgn0032034.html FBgn0062872 protein_coding_gene 0007099=centriole replication 0005814=centriole "BcDNA:SD16838, Rcd4, CG17295, Reduction in Cnn Dots 4" "IPR029135=Protein phosphatase 1 regulatory subunit 35, C-terminal" CG17295 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0065869 l(2)SH0260 lethal (2) SH0260 http://flybase.net/reports/FBgn0065869.html gene l(2)SH2 0260 16-Dec-15 2015_12 "lethal,recessive" FBgn0267327 Acp33A Accessory gland-specific peptide 33A http://flybase.net/reports/FBgn0267327.html "FBgn0023414, FBgn0032367, FBgn0052952" protein_coding_gene 0005179=hormone activity "0045434=negative regulation of female receptivity, post-mating, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0005576=extracellular region" "Accessory gland protein 33A, CG32952, CG32952-A, unnamed, CG6555, Acp33a, CG15841" CG6555 16-Dec-15 2015_12 adult stage | male " male accessory gland main cell

, male accessory gland

" FBgn0259285 EP-800 http://flybase.net/reports/FBgn0259285.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta" FBgn0050428 CG30428 http://flybase.net/reports/FBgn0050428.html FBgn0064772 protein_coding_gene BcDNA:SD21514 IPR028002=Myb/SANT-like DNA-binding domain CG30428 16-Dec-15 2015_12 viable FBgn0266474 pistachio http://flybase.net/reports/FBgn0266474.html gene 16-Dec-15 2015_12 lethal "egg chamber,cell non-autonomous,somatic clone,oocyte,germline clone" FBgn0044074 E(rst)I2 E(rst)I2 http://flybase.net/reports/FBgn0044074.html gene 0001745=compound eye morphogenesis I2 16-Dec-15 2015_12 viable eye FBgn0044092 E(rst)D19 E(rst)D19 http://flybase.net/reports/FBgn0044092.html gene 0001745=compound eye morphogenesis D19 16-Dec-15 2015_12 viable "eye,cone cell,primary pigment cell,ectopic" FBgn0045064 bwa brain washing http://flybase.net/reports/FBgn0045064.html FBgn0032842 protein_coding_gene 0017040=ceramidase activity "0019216=regulation of lipid metabolic process, 0046514=ceramide catabolic process, 0006665=sphingolipid metabolic process, 0007420=brain development" "0005783=endoplasmic reticulum, 0016021=integral component of membrane" "CG13969, Brain washing, 38B.6, Brainwashing, dacer, brainwashing" IPR008901=Ceramidase CG13969 16-Dec-15 2015_12 ENSDARG00000010347(acer1) "YPL087W(YDC1),YBR183W(YPC1)" WBGene00020947(W02F12.2) ENSXETG00000024487(ACER2) ENSMUSG00000038007(Acer2) ENSG00000177076(ACER2) "viable,fertile,developmental rate defective,long lived,oxidative stress response defective" "mushroom body beta-lobe,adult mushroom body beta'-lobe,ellipsoid body" FBgn0037028 CG3618 http://flybase.net/reports/FBgn0037028.html protein_coding_gene 0004383=guanylate cyclase activity "0008360=regulation of cell shape, 0007015=actin filament organization, 0007155=cell adhesion" GYCb100B CG3618 16-Dec-15 2015_12 "viable,fertile" FBgn0062594 Mod(var)1540 Mod(var)1540 http://flybase.net/reports/FBgn0062594.html gene 0006342=chromatin silencing 1540 16-Dec-15 2015_12 suppressor of variegation FBgn0022754 amputee amputee http://flybase.net/reports/FBgn0022754.html gene 16-Dec-15 2015_12 visible "leg,femur" FBgn0032072 CG9483 http://flybase.net/reports/FBgn0032072.html FBgn0044717 protein_coding_gene anon-WO0140519.161 CG9483 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0040281 Aplip1 APP-like protein interacting protein 1 http://flybase.net/reports/FBgn0040281.html "FBgn0020447, FBgn0026251, FBgn0035188" protein_coding_gene "0019901=protein kinase binding, 0008432=JUN kinase binding, 0019894=kinesin binding, 0005515=protein binding" "0048491=retrograde synaptic vesicle transport, 0048812=neuron projection morphogenesis, 0007254=JNK cascade, 0046328=regulation of JNK cascade, 0019896=axon transport of mitochondrion, 2000331=regulation of terminal button organization, 0048490=anterograde synaptic vesicle transport" 0030424=axon "ek4, CG1200, c-Jun N-terminal kinase (JNK)-interacting protein, Ek4, dp1, JIP1, jip1, EK4, JNK interacting protein-1, aplip1, Jip1/2, E(Khc)ek4, SP512, APLIP1" "IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001452=SH3 domain" CG1200 16-Dec-15 2015_12 WBGene00002176(jip-1) "ENSXETG00000001025(MAPK8IP1),ENSXETG00000015685(MAPK8IP2)" "ENSMUSG00000022619(Mapk8ip2),ENSMUSG00000027223(Mapk8ip1)" " larval stage--adult stage , adult stage , embryonic stage | mid-late , embryonic stage | late " " head

, embryonic central nervous system

, embryonic brain

" "viable,neuroanatomy defective,paralytic,fertile,posterior,lethal" "NMJ bouton,NMJ bouton | larval stage,axon,mitochondrion,axonFpa2),axonD42" FBgn0000954 fs(2)E1 female sterile (2) E1 http://flybase.net/reports/FBgn0000954.html gene fs2.1 16-Dec-15 2015_12 female sterile "egg,gonad,dorsal appendage" FBgn0011208 bob bobble http://flybase.net/reports/FBgn0011208.html gene "0007140=male meiosis, 0048477=oogenesis, 0030717=karyosome formation, 0007283=spermatogenesis" ms(3)06208 16-Dec-15 2015_12 "viable,female fertile,male fertile,male sterile,recessive,partially lethal - majority die,meiotic cell cycle defective,lethal,female sterile,germline clone" "Nebenkern,karyosome,germline clone,egg chamber" FBgn0003926 snRNA:U3:22A small nuclear RNA U3 at 22A http://flybase.net/reports/FBgn0003926.html "FBgn0003925, FBgn0051927" snRNA_gene "0000398=mRNA splicing, via spliceosome" "K7, snRNA:U3, snRNA2, small nuclear RNA U3, CR31927, snRNA3, U3snRNA22A, snRNA[[2]], U3snRNA" CR31927 16-Dec-15 2015_12 FBgn0263024 CG43319 http://flybase.net/reports/FBgn0263024.html FBgn0039540 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG12879 CG43319 16-Dec-15 2015_12 FBgn0034957 CG3121 http://flybase.net/reports/FBgn0034957.html FBgn0044775 protein_coding_gene 0008017=microtubule binding 0007017=microtubule-based process 0005875=microtubule associated complex anon-WO0140519.109 IPR006802=Radial spokehead-like protein CG3121 16-Dec-15 2015_12 "ENSDARG00000067606(LOC100148286),ENSDARG00000008597" ENSXETG00000019096(rshl1) "ENSMUSG00000039552(Rsph4a),ENSMUSG00000040866(Rsph6a)" "ENSG00000111834(RSPH4A),ENSG00000104941(RSPH6A)" viable FBgn0034976 CG4049 http://flybase.net/reports/FBgn0034976.html FBgn0041704 protein_coding_gene 0005524=ATP binding 0006281=DNA repair "BEST:LD04705, Arip4, R-gene" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain" CG4049 16-Dec-15 2015_12 WBGene00007761(rad-26) ENSMUSG00000040661(Rad54l2) ENSG00000164080(RAD54L2) viable FBgn0050200 tRNA:CR30200 transfer RNA:CR30200 http://flybase.net/reports/FBgn0050200.html FBgn0060275 tRNA_gene 0033456=GCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR30200, tRNA[[Ala]], chr2R.trna52-AlaCGC, tRNA:A:CGC:AE002575-c, AE002575.trna8-AlaCGC" CR30200 16-Dec-15 2015_12 FBgn0039471 CG6295 http://flybase.net/reports/FBgn0039471.html protein_coding_gene "0008970=phosphatidylcholine 1-acylhydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "DmelL6, Triglyceride lipase" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family, IPR002334=Vespid venom allergen phospholipase A1" CG6295 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) viable DRSC16012 K -0.112804712 0.279279894 -0.369200931 0.283664843 1.236918231 2.104315067 FBgn0085544 CG40955 http://flybase.net/reports/FBgn0085544.html FBan0040955 protein_coding_gene 16-Dec-15 2015_12 FBgn0029712 CG15912 http://flybase.net/reports/FBgn0029712.html protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process 24639695 "IPR006439=HAD hydrolase, subfamily IA, IPR011949=HAD-superfamily hydrolase, subfamily IA, REG-2-like, IPR023214=HAD-like domain" CG15912 16-Dec-15 2015_12 ENSDARG00000053934(si:ch211-10e8.6) YMR130W() WBGene00010481(K01G5.10) ENSXETG00000023477(HDHD3) ENSMUSG00000038422(Hdhd3) ENSG00000119431(HDHD3) viable FBgn0038873 CG5892 http://flybase.net/reports/FBgn0038873.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG5892 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" "viable,fertile" FBgn0015849 anon-10Cb anon-10Cb http://flybase.net/reports/FBgn0015849.html gene unnamed 16-Dec-15 2015_12 FBgn0261389 p1130 http://flybase.net/reports/FBgn0261389.html gene 16-Dec-15 2015_12 "stress response defective,long lived,dominant" FBgn0033875 CG6357 http://flybase.net/reports/FBgn0033875.html protein_coding_gene 0004197=cysteine-type endopeptidase activity "IPR013128=Peptidase C1A, IPR013201=Cathepsin propeptide inhibitor domain (I29)" CG6357 16-Dec-15 2015_12 viable FBgn0022318 l(1)B8.5 lethal (1) B8.5 http://flybase.net/reports/FBgn0022318.html gene B8.5 16-Dec-15 2015_12 "lethal,recessive" FBgn0040291 Roc1b Regulator of cullins 1b http://flybase.net/reports/FBgn0040291.html "FBgn0035135, FBgn0047337" protein_coding_gene "0008270=zinc ion binding, 0097602=cullin family protein binding, 0061630=ubiquitin protein ligase activity" "0030317=sperm motility, 0016567=protein ubiquitination, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0019915=lipid storage" 0031463=Cul3-RING ubiquitin ligase complex "BcDNA:AT21612, Roc, dRoc1b, ROC1B, ROC2, CG16988, roc1b, Roc1b, ROC1b" "IPR001841=Zinc finger, RING-type, IPR024766=Zinc finger, RING-H2-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG16988 16-Dec-15 2015_12 YOL133W(HRT1) " embryonic stage -- adult stage , larval stage " " organism

, dorsal mesothoracic disc

ubiquitous " "viable,male sterile,male semi-sterile,increased cell death,somatic clone" "spermatozoon,spermatid" FBgn0010806 l(3)03644 lethal (3) 03644 http://flybase.net/reports/FBgn0010806.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0060564 l(3)S096516b lethal (3) S096516b http://flybase.net/reports/FBgn0060564.html gene 0965/16 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039980 CG18160 http://flybase.net/reports/FBgn0039980.html FBan0018160 protein_coding_gene 16-Dec-15 2015_12 FBgn0024608 olfJ11 olfactory J11 http://flybase.net/reports/FBgn0024608.html gene 16-Dec-15 2015_12 smell perception defective FBgn0038600 CG12364 http://flybase.net/reports/FBgn0038600.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040018 CG12631 http://flybase.net/reports/FBgn0040018.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031479 Prx6005 Peroxiredoxin 6005 http://flybase.net/reports/FBgn0031479.html protein_coding_gene "0004602=glutathione peroxidase activity, 0008379=thioredoxin peroxidase activity, 0016209=antioxidant activity, 0004601=peroxidase activity" "0055114=oxidation-reduction process, 0042744=hydrogen peroxide catabolic process, 0045454=cell redox homeostasis" 0005829=cytosol "DPx-6005, 153181_at, CG3083, GM04269p, DPx6005" "IPR012336=Thioredoxin-like fold, IPR024706=Peroxiredoxin, AhpC-type, IPR019479=Peroxiredoxin, C-terminal, IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant" CG3083 16-Dec-15 2015_12 "ENSDARG00000043511(prdx6),ENSDARG00000043530" YBL064C(PRX1) WBGene00021401(prdx-6) ENSXETG00000000525(prdx6-2) "ENSMUSG00000026701(Prdx6),ENSMUSG00000050114(Prdx6-rs1-ps)" ENSG00000117592(PRDX6) "viable,body color defective" mesothoracic tergum FBgn0040236 c11.1 c11.1 http://flybase.net/reports/FBgn0040236.html FBgn0030123 protein_coding_gene "C11.1, CG12132" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG12132 16-Dec-15 2015_12 ENSDARG00000016573(heatr7a) WBGene00016418(C34G6.1) ENSXETG00000005685() "ENSMUSG00000022558,ENSMUSG00000079429,ENSMUSG00000022155(Heatr7b2)" "ENSG00000179832(HEATR7A),ENSG00000185038(HEATR7B1),ENSG00000171495(HEATR7B2)" "viable,fertile" FBgn0028213 l(3)S010102a lethal (3) S010102a http://flybase.net/reports/FBgn0028213.html gene "0101/02, l(3)S010102" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0029995 CG2256 http://flybase.net/reports/FBgn0029995.html protein_coding_gene 0005509=calcium ion binding "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR028846=Recoverin family" CG2256 16-Dec-15 2015_12 ENSDARG00000061377(si:ch211-173p18.9) ENSXETG00000022013(TGas107m05.1) "ENSMUSG00000068617(Efcab1),ENSMUSG00000008307(1700109H08Rik)" ENSG00000034239(EFCAB1) viable FBgn0267733 CR46064 http://flybase.net/reports/FBgn0267733.html non_protein_coding_gene CR46064 16-Dec-15 2015_12 FBgn0069098 mus327 mutagen-sensitive 327 http://flybase.net/reports/FBgn0069098.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0004204 l(3)84Eb lethal (3) 84Eb http://flybase.net/reports/FBgn0004204.html gene 16-Dec-15 2015_12 lethal FBgn0015966 l(2)46DEd lethal (2) 46DEd http://flybase.net/reports/FBgn0015966.html gene group 8 16-Dec-15 2015_12 "lethal,recessive" FBgn0020563 anon-VI-C4 anon-VI-C4 http://flybase.net/reports/FBgn0020563.html gene 16-Dec-15 2015_12 "Bolwig organ,Bolwig nerve" FBgn0259836 Su(Ste):CR42405 Su(Ste):CR42405 http://flybase.net/reports/FBgn0259836.html non_protein_coding_gene CR42405 CR42405 16-Dec-15 2015_12 FBgn0012043 Bom Bombyxin http://flybase.net/reports/FBgn0012043.html gene 16-Dec-15 2015_12 FBgn0022165 l(2)k05614 lethal (2) k05614 http://flybase.net/reports/FBgn0022165.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053380 5SrRNA:CR33380 5SrRNA:CR33380 http://flybase.net/reports/FBgn0053380.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33380 CR33380 16-Dec-15 2015_12 FBgn0061070 l(3)S018611b lethal (3) S018611b http://flybase.net/reports/FBgn0061070.html gene 0186/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0262989 CR43297 http://flybase.net/reports/FBgn0262989.html non_protein_coding_gene lincRNA.967 CR43297 16-Dec-15 2015_12 FBgn0000246 c(3)G crossover suppressor on 3 of Gowen http://flybase.net/reports/FBgn0000246.html "FBgn0038362, FBgn0063641" protein_coding_gene 0007131=reciprocal meiotic recombination 0000795=synaptonemal complex "c(3)g, CG17604, Crossover suppressor on 3 of Gowen, crossover suppressor on 3 of Gowan, crossover suppressor in chromosome 3 of Gowen, cx, c3G, C(3)G, C3G" CG17604 16-Dec-15 2015_12 adult stage && O | stage S1-7 presumptive oocyte && oocyte

"meiotic cell cycle defective,female,wild-type,recessive,viable" "synaptonemal complex,synaptonemal complexnos.UTR.THsimVP16, c(3)G68,synaptonemal complexG68)nos.UTR.THsimVP16,oocyte & meiosis & nuclear chromosome,nurse cell & nuclear chromosome,germarium & nuclear chromosome,synaptonemal complexnos.UTR.THsimVP16, c(3)GCdel.UAS.PT.TZzzzFLAG,synaptonemal complexGCdel.UAS.PT.TZzzzFLAG)nos.UTR.THsimVP16,polytene chromosome chromocenter,meiotic cell cycle,meiotic metaphase I,meiotic anaphase I" FBgn0058064 ARY Aldehyde reductase Y http://flybase.net/reports/FBgn0058064.html FBan0040064 protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process "ARY, aldehyde reductase Y, CG40064" "IPR023210=NADP-dependent oxidoreductase domain, IPR020471=Aldo/keto reductase subgroup, IPR018170=Aldo/keto reductase, conserved site, IPR001395=Aldo/keto reductase" CG40064 16-Dec-15 2015_12 FBgn0005351 stx streakex http://flybase.net/reports/FBgn0005351.html gene 16-Dec-15 2015_12 "partially lethal - majority die,body color defective" thorax FBgn0263542 mir-4954 mir-4954 stem loop http://flybase.net/reports/FBgn0263542.html miRNA_gene "dme-mir-4954, CR43527" CR43527 16-Dec-15 2015_12 FBgn0262647 Nup160 Nucleoporin 160kD http://flybase.net/reports/FBgn0262647.html "FBgn0065273, FBgn0260937, FBgn0250730, FBgn0032347" protein_coding_gene "0005487=nucleocytoplasmic transporter activity, 0005515=protein binding" "0006406=mRNA export from nucleus, 0007184=SMAD protein import into nucleus" 0031080=nuclear pore outer ring "nuclear pore protein 160, Nucleoporin 160, CG4738, l(2)SH2 2055, Nup, Nup160[mel], nup160, l(2)SH2055, lethal (2) SH2055" CG4738 16-Dec-15 2015_12 ENSXETG00000007917() ENSMUSG00000051329(Nup160) ENSG00000030066(NUP160) DRSC02774 E -1.482368884 -0.124106381 -3.120267687 -1.625863346 -0.336750099 -0.341110484 FBgn0036730 qjt quijote http://flybase.net/reports/FBgn0036730.html protein_coding_gene 0019789=SUMO transferase activity "0006281=DNA repair, 0000724=double-strand break repair via homologous recombination" "0030915=Smc5-Smc6 complex, 0005634=nucleus" "Quijote, CG13732" IPR026846=E3 SUMO-protein ligase Nse2 (Mms21) CG13732 16-Dec-15 2015_12 WBGene00022881(ZK1248.11) ENSMUSG00000059586(Nsmce2) ENSG00000156831(NSMCE2) FBgn0259259 C719.2 http://flybase.net/reports/FBgn0259259.html gene 16-Dec-15 2015_12 visible "wing hair,wing,wing vein" FBgn0261813 CR42755 http://flybase.net/reports/FBgn0261813.html non_protein_coding_gene CG42755 CR42755 16-Dec-15 2015_12 FBgn0033440 CG10459 http://flybase.net/reports/FBgn0033440.html protein_coding_gene 0005102=receptor binding 0030512=negative regulation of transforming growth factor beta receptor signaling pathway "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site" CG10459 16-Dec-15 2015_12 viable DRSC05991 K -0.746006084 0.843134801 -0.254654608 0.096453341 -1.534710026 0.721058438 FBgn0011177 l(1)291-68 lethal (1) 291-68 http://flybase.net/reports/FBgn0011177.html FBgn0010199 gene 291-68 16-Dec-15 2015_12 "lethal,recessive" FBgn0259397 EP-297.2 http://flybase.net/reports/FBgn0259397.html gene 16-Dec-15 2015_12 visible wing vein FBgn0013284 Jhbp-80 Juvenile hormone binding protein - 80kD http://flybase.net/reports/FBgn0013284.html gene 16-Dec-15 2015_12 FBgn0000746 fs(1)A321 female sterile (1) A321 http://flybase.net/reports/FBgn0000746.html gene 16-Dec-15 2015_12 "female sterile,recessive,visible" "egg,macrochaeta" FBgn0020821 l(3)98Di lethal (3) 98Di http://flybase.net/reports/FBgn0020821.html gene M311 16-Dec-15 2015_12 "lethal,recessive" FBgn0020345 Clch Chloride channel http://flybase.net/reports/FBgn0020345.html gene "unnamed, anon-49ABa" 16-Dec-15 2015_12 FBgn0001612 Grip91 Gamma-tubulin ring protein 91 http://flybase.net/reports/FBgn0001612.html "FBgn0026429, FBgn0040196, FBgn0066830" protein_coding_gene "0008017=microtubule binding, 0051011=microtubule minus-end binding, 0043015=gamma-tubulin binding" "0051297=centrosome organization, 0043147=meiotic spindle stabilization, 0007017=microtubule-based process, 0007052=mitotic spindle organization, 0022008=neurogenesis, 0007020=microtubule nucleation, 0007140=male meiosis" "0008275=gamma-tubulin small complex, 0005875=microtubule associated complex, 0000922=spindle pole, 0072686=mitotic spindle, 0005813=centrosome" "DGrip91, lethal (1) discs degenerate 4, anon-WO03040301.197, Dgrip91, Dgrips91, GRIP91, dGRIP91, l(1)d.deg.-4, l(1)d deg-4, GCP3, l(1)d.deg.4, l(1)G0122, dd4, l(1)dd4, Grip91, Dgrip9, CG10988, gamma-tubulin ring protein 91, Dd4" "IPR007259=Gamma-tubulin complex component protein, IPR015697=Gamma-tubulin complex component/Spindle pole body component" CG10988 16-Dec-15 2015_12 ENSDARG00000029133(tubgcp3) YNL126W(SPC98) ENSXETG00000001903(TUBGCP3) ENSMUSG00000000759(Tubgcp3) ENSG00000126216(TUBGCP3) embryonic stage "wild-type,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,meiotic cell cycle defective,male limited,male sterile,cytokinesis defective,female sterile,visible,partially lethal - majority live,sterile,partially,neuroanatomy defective" "imaginal disc,cell cycle,embryonic/larval brain,mitotic cell cycle,centriole,pericentriolar material,centrosome,spermatocyte & spindle,wing,head bristle,adult thorax & macrochaeta,scutellar bristle,adult abdomen,macrochaeta,abdominal segment,ganglion mother cell,chaeta,supernumerary" DRSC20249 IE 2.294466383 0.74518313 1.954009186 0.180643229 -0.063889585 1.153351715 FBgn0261596 RpS24 Ribosomal protein S24 http://flybase.net/reports/FBgn0261596.html "FBgn0034751, FBgn0062995, FBgn0065274" protein_coding_gene "0003735=structural constituent of ribosome, 0000166=nucleotide binding" 0006412=translation "0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "CG3751, 40S ribosomal protein S24, l(2)SH2053, Rp S24, lethal (2) SH2053, BcDNA:RE59324, S24, l(2)SH2 2053" "IPR001976=Ribosomal protein S24e, IPR018098=Ribosomal S24e conserved site, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR012678=Ribosomal protein L23/L15e core domain" CG3751 16-Dec-15 2015_12 ENSDARG00000039347(rps24) "YER074W(RPS24A),YIL069C(RPS24B)" WBGene00004493(rps-24) ENSXETG00000018137(RPS24) "ENSMUSG00000025290(Rps24),ENSMUSG00000062284,ENSMUSG00000069125(Rps24-ps2)" ENSG00000138326(RPS24) DRSC28412 IEK -1.681035961 -2.296661036 1.00233819 -4.236716912 4.265953391 3.233140018 FBgn0029056 l(1)G0449 lethal (1) G0449 http://flybase.net/reports/FBgn0029056.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" third instar larva FBgn0011853 tRNA:E4:62Ac transfer RNA:glu4:62Ac http://flybase.net/reports/FBgn0011853.html "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052325, FBgn0060248" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033460=GAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:E:CTC:AE002584-f, tRNA:E4, tRNA:Glu, CR32325, chr3L.trna8-GluCTC, tRNA:glu4:62Ac, AE002584.trna8-GluCTC" CR32325 16-Dec-15 2015_12 FBgn0058086 CG40086 http://flybase.net/reports/FBgn0058086.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060688 l(3)S074510b lethal (3) S074510b http://flybase.net/reports/FBgn0060688.html gene 0745/10 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041175 Ubx::Hrob\Lox2 Lox2 http://flybase.net/reports/FBgn0041175.html engineered_fusion_gene 16-Dec-15 2015_12 "leg,ectopic,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0014043 Su(tor)2-15 Su(tor)2-15 http://flybase.net/reports/FBgn0014043.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031443 Prosë_4R2 Proteasome ë_4 subunit-related 2 http://flybase.net/reports/FBgn0031443.html FBgn0044760 protein_coding_gene 0004298=threonine-type endopeptidase activity 0006511=ubiquitin-dependent protein catabolic process 0005839=proteasome core complex "Proteasome beta4R2 subunit, CG17302, anon-WO0140519.122, beta4R2" "IPR016050=Proteasome beta-type subunit, conserved site, IPR001353=Proteasome, subunit alpha/beta, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR023333=Proteasome B-type subunit" CG17302 16-Dec-15 2015_12 YER012W(PRE1) WBGene00003950(pbs-4) ENSXETG00000009668(PSMB2) ENSMUSG00000028837(Psmb2) ENSG00000126067(PSMB2) viable FBgn0260574 MENE-GG12 http://flybase.net/reports/FBgn0260574.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0265199 CG44259 http://flybase.net/reports/FBgn0265199.html protein_coding_gene CG44259 16-Dec-15 2015_12 FBgn0259641 B0432 http://flybase.net/reports/FBgn0259641.html gene 16-Dec-15 2015_12 visible wing FBgn0038741 CG17186 http://flybase.net/reports/FBgn0038741.html protein_coding_gene "IPR015880=Zinc finger, C2H2-like" CG17186 16-Dec-15 2015_12 viable FBgn0035462 IntS10 Integrator 10 http://flybase.net/reports/FBgn0035462.html protein_coding_gene 0016180=snRNA processing 0032039=integrator complex "Int10, CG1120" "IPR026164=Integrator complex subunit 10, IPR016024=Armadillo-type fold" CG1120 16-Dec-15 2015_12 ENSDARG00000043031(ints10) ENSXETG00000004462(INTS10) ENSMUSG00000031864(Ints10) ENSG00000104613(INTS10) "viable,visible" trichogen cell FBgn0085157 l(3)S000718 l(3)S000718 http://flybase.net/reports/FBgn0085157.html gene 16-Dec-15 2015_12 FBgn0034127 CG7848 http://flybase.net/reports/FBgn0034127.html protein_coding_gene "0051287=NAD binding, 0004473=malate dehydrogenase (decarboxylating) (NADP+) activity, 0004471=malate dehydrogenase (decarboxylating) (NAD+) activity" "0055114=oxidation-reduction process, 0006108=malate metabolic process" "IPR012301=Malic enzyme, N-terminal domain, IPR016040=NAD(P)-binding domain, IPR001891=Malic oxidoreductase, IPR012302=Malic enzyme, NAD-binding" CG7848 16-Dec-15 2015_12 YKL029C(MAE1) FBgn0267983 CR46250 http://flybase.net/reports/FBgn0267983.html non_protein_coding_gene CR46250 16-Dec-15 2015_12 FBgn0262200 mir-962 mir-962 stem loop http://flybase.net/reports/FBgn0262200.html miRNA_gene "0006955=immune response, 0060259=regulation of feeding behavior" "dme-mir-962, 962, miR-962, CR42907" CR42907 16-Dec-15 2015_12 viable FBgn0266853 CR45314 http://flybase.net/reports/FBgn0266853.html non_protein_coding_gene CR45314 16-Dec-15 2015_12 FBgn0262735 Imp IGF-II mRNA-binding protein http://flybase.net/reports/FBgn0262735.html "FBgn0030235, FBgn0025229, FBgn0026687, FBgn0044592, FBgn0086543" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003730=mRNA 3'-UTR binding" "0005975=carbohydrate metabolic process, 0007399=nervous system development, 0007283=spermatogenesis, 0051124=synaptic growth at neuromuscular junction, 0048680=positive regulation of axon regeneration, 0016322=neuron remodeling, 0000398=mRNA splicing, via spliceosome, 0042594=response to starvation" "0005737=cytoplasm, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0030424=axon, 0043025=neuronal cell body" "IGF2BP1, CG1691, imp, MRE11, KH-domain protein, ORE-9, insulin-like growth factor II, IMP-1, anon-fast-evolving-2B3, cg1691, Insulin-like Growth Factor 2 mRNA Binding Protein 1, IGF-II, mRNA-like ncRNA in embryogenesis 11, IGF-II messenger RNA binding protein, IMP, anon-WO0140519.39, l(1)G0072, anon-EST:fe2B3, dIMP, mre11" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR004088=K Homology domain, type 1, IPR004087=K Homology domain, IPR000504=RNA recognition motif domain" CG1691 16-Dec-15 2015_12 "ENSDARG00000061478(igf2bp1),ENSDARG00000010266(igf2bp3),ENSDARG00000003421(igf2bp2a),ENSDARG00000061661(LOC557028)" WBGene00010908(M88.5) ENSXETG00000007396(TEgg011n04.1) "ENSMUSG00000013415(Igf2bp1),ENSMUSG00000029814(Igf2bp3),ENSMUSG00000033581(Igf2bp2)" "ENSG00000159217(IGF2BP1),ENSG00000136231(IGF2BP3),ENSG00000073792(IGF2BP2)" FBgn0087015 l(3)61Dc lethal (3) 61Dc http://flybase.net/reports/FBgn0087015.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal" FBgn0065097 snmRNA:357 small non-messenger RNA 357 http://flybase.net/reports/FBgn0065097.html FBgn0053659 non_protein_coding_gene "Dm-357, CR33659" CR33659 16-Dec-15 2015_12 FBgn0264992 CR44143 http://flybase.net/reports/FBgn0264992.html non_protein_coding_gene CR44143 16-Dec-15 2015_12 FBgn0061361 CG33786 http://flybase.net/reports/FBgn0061361.html "FBgn0034536, FBgn0050144, FBgn0053005, FBgn0053786, FBtr0086250, FBtr0086251, FBpp0085563" protein_coding_gene "0045182=translation regulator activity, 0003725=double-stranded RNA binding" 0006412=translation "CG33005, CG33005-ORFB, CG33005ORFB, CG10438, CG10438b, Dromel_CG33786_FBtr0091786_mORF" "IPR017945=DHBP synthase RibB-like alpha/beta domain, IPR006070=YrdC-like domain" CG33786 16-Dec-15 2015_12 ENSDARG00000041428(zgc:162301) YGL169W(SUA5) WBGene00012997(Y48C3A.18) ENSXETG00000014420(Q5FVA3_XENTR) ENSMUSG00000028889(Yrdc) ENSG00000196449(YRDC) FBgn0034304 CG5742 http://flybase.net/reports/FBgn0034304.html protein_coding_gene 0022008=neurogenesis "IPR020683=Ankyrin repeat-containing domain, IPR021832=Ankyrin repeat domain-containing protein 13, IPR002110=Ankyrin repeat" CG5742 16-Dec-15 2015_12 ENSDARG00000042444(ankrd13c) WBGene00015301(C01F1.6) ENSXETG00000009602(ankrd12c) ENSMUSG00000039988(Ankrd13c) ENSG00000118454(ANKRD13C) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0011222 gru gruyere http://flybase.net/reports/FBgn0011222.html gene 0007286=spermatid development 16-Dec-15 2015_12 "female sterile,male sterile,partially lethal - majority die" Nebenkern FBgn0064187 ctu count-up http://flybase.net/reports/FBgn0064187.html gene 0007284=spermatogonial cell division 16-Dec-15 2015_12 FBgn0019651 su(mbm) suppressor of mushroom body miniature http://flybase.net/reports/FBgn0019651.html gene 16-Dec-15 2015_12 FBgn0025620 CG13360 http://flybase.net/reports/FBgn0025620.html protein_coding_gene EG:34F3.5 "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG13360 16-Dec-15 2015_12 "WBGene00007810(C29F7.1),WBGene00007811(C29F7.2),WBGene00014192(nhr-246)" viable FBgn0267053 CR45497 http://flybase.net/reports/FBgn0267053.html pseudogene_attribute CR45497 16-Dec-15 2015_12 FBgn0034552 CG17999 http://flybase.net/reports/FBgn0034552.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG17999 16-Dec-15 2015_12 viable FBgn0267688 CR46024 http://flybase.net/reports/FBgn0267688.html non_protein_coding_gene CR46024 16-Dec-15 2015_12 FBgn0086704 stops slow termination of phototransduction http://flybase.net/reports/FBgn0086704.html "FBgn0051006, FBgn0039824, FBgn0039823, FBgn0039822, FBgn0026167" protein_coding_gene "0016059=deactivation of rhodopsin mediated signaling, 0035556=intracellular signal transduction, 0007605=sensory perception of sound" "CG15558, suppressor (rdgB) 69, CG15559, su(rdgB)69, CG15557, CG31006" IPR001496=SOCS box domain CG31006 16-Dec-15 2015_12 FBgn0046640 anon-38D.4 anon-38D.4 http://flybase.net/reports/FBgn0046640.html gene 38D.4 16-Dec-15 2015_12 FBgn0002541 ld loboid http://flybase.net/reports/FBgn0002541.html gene 16-Dec-15 2015_12 "visible,viable,reduced,dominant,partially" "eye,ommatidium" FBgn0263494 CR43483 http://flybase.net/reports/FBgn0263494.html pseudogene_attribute CR43483 16-Dec-15 2015_12 FBgn0032519 CG16957 http://flybase.net/reports/FBgn0032519.html protein_coding_gene IPR001199=Cytochrome b5-like heme/steroid binding domain CG16957 16-Dec-15 2015_12 YPL170W(DAP1) "viable,fertile" FBgn0029924 CG4586 http://flybase.net/reports/FBgn0029924.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0003997=acyl-CoA oxidase activity, 0003995=acyl-CoA dehydrogenase activity" 0006635=fatty acid beta-oxidation 0005777=peroxisome acyl-coenzyme A oxidase "IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320=Acyl-coenzyme A oxidase, N-terminal, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR002655=Acyl-CoA oxidase, C-terminal, IPR012258=Acyl-CoA oxidase, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal" CG4586 16-Dec-15 2015_12 ENSDARG00000014727(acox1) "WBGene00010336(F59F4.1),WBGene00009104(F25C8.1),WBGene00008564(F08A8.1),WBGene00008567(F08A8.4),WBGene00008566(F08A8.3),WBGene00008565(F08A8.2),WBGene00008167(C48B4.1)" "ENSXETG00000012601(acox1),ENSXETG00000023676(acox2)" ENSMUSG00000020777(Acox1) ENSG00000161533(ACOX1) "viable,fertile" FBgn0086068 snoRNA:Or-CD12 http://flybase.net/reports/FBgn0086068.html snoRNA_gene "DmOr_cd12(DmU24), CR34697, dM_28s.017, orphan CD12, DmU24" CR34697 16-Dec-15 2015_12 FBgn0063413 l(3)3450-J lethal (3) 3450-J http://flybase.net/reports/FBgn0063413.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015738 I-55 screen I - clone 55 http://flybase.net/reports/FBgn0015738.html gene 16-Dec-15 2015_12 FBgn0065317 l(2)SH1924 lethal (2) SH1924 http://flybase.net/reports/FBgn0065317.html gene l(2)SH2 1924 16-Dec-15 2015_12 "lethal,recessive" FBgn0065641 l(2)SH0759 lethal (2) SH0759 http://flybase.net/reports/FBgn0065641.html gene l(2)SH2 0759 16-Dec-15 2015_12 "lethal,recessive" FBgn0014922 anon-72ABf anon-72ABf http://flybase.net/reports/FBgn0014922.html gene 16-Dec-15 2015_12 FBgn0032001 CG8360 http://flybase.net/reports/FBgn0032001.html FBgn0063128 protein_coding_gene "0004126=cytidine deaminase activity, 0008270=zinc ion binding" 0009972=cytidine deamination BcDNA:LP03131 "IPR006262=Cytidine deaminase, homotetrameric, IPR002125=Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016193=Cytidine deaminase-like" CG8360 16-Dec-15 2015_12 "ENSDARG00000038199(cda),ENSDARG00000036426(zgc:103586)" YLR245C(CDD1) "WBGene00000392(cdd-2),WBGene00000391(cdd-1)" ENSMUSG00000028755(Cda) ENSG00000158825(CDA) viable DRSC03085 K -0.227651764 -0.449098085 1.438443853 0.174876159 0.90255534 1.700501246 FBgn0028202 l(3)S018405 lethal (3) S018405 http://flybase.net/reports/FBgn0028202.html gene 0184/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage" FBgn0000380 cs creased http://flybase.net/reports/FBgn0000380.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" "wing,1st posterior cell" FBgn0037656 CG11986 http://flybase.net/reports/FBgn0037656.html protein_coding_gene IPR003738=SOS response associated peptidase (SRAP) CG11986 16-Dec-15 2015_12 YMR114C() ENSXETG00000024746(dc12) ENSMUSG00000030060(8430410A17Rik) ENSG00000183624(C3orf37) "viable,fertile" FBgn0022787 Hel89B Helicase 89B http://flybase.net/reports/FBgn0022787.html protein_coding_gene "0005524=ATP binding, 0004003=ATP-dependent DNA helicase activity, 0004386=helicase activity" "0019730=antimicrobial humoral response, 0042742=defense response to bacterium, 0008063=Toll signaling pathway, 0045087=innate immune response, 0006963=positive regulation of antibacterial peptide biosynthetic process" "BTAF1, CG4261, Mot1, Helicase89B, 89B, 89B Helicase, 89B helicase" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain, IPR022707=Domain of unknown function DUF3535" CG4261 16-Dec-15 2015_12 ENSDARG00000060089(btaf1) YPL082C(MOT1) WBGene00000274(btf-1) ENSMUSG00000040565(Btaf1) ENSG00000095564(BTAF1) embryonic stage -- adult stage ", embryonic stage | stage >=12 , embryonic stage | early " " unfertilized egg

, longitudinal connective

,

ubiquitous , embryonic brain

, ventral nerve cord

" "visible,recessive,male sterile,partially lethal - majority die,viable" "abdominal sternite 6,male" FBgn0266441 CG45071 http://flybase.net/reports/FBgn0266441.html "FBgn0262707, FBgn0036478, FBgn0046343, FBgn0046344, FBgn0262154" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "CG6854, Polypeptide A" "IPR006578=MADF domain, IPR004210=BESS motif" CG45071 16-Dec-15 2015_12 FBgn0043806 CG32032 http://flybase.net/reports/FBgn0043806.html "FBgn0052032, FBgn0064812" protein_coding_gene "BEST:GH25183, BcDNA:RH42907" IPR011038=Calycin-like CG32032 16-Dec-15 2015_12 viable FBgn0023078 h::sna h::sna http://flybase.net/reports/FBgn0023078.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,female" FBgn0065563 l(2)SH0983 lethal (2) SH0983 http://flybase.net/reports/FBgn0065563.html gene "SH0983, l(2)SH2 0983" 16-Dec-15 2015_12 "lethal,recessive" FBgn0005697 l(3)88Ac lethal (3) 88Ac http://flybase.net/reports/FBgn0005697.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,cold sensitive" FBgn0028306 l(1)G0375 lethal (1) G0375 http://flybase.net/reports/FBgn0028306.html gene 16-Dec-15 2015_12 "partially lethal - majority die,male,female,recessive" FBgn0027133 l(3)99Ba lethal (3) 99Ba http://flybase.net/reports/FBgn0027133.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0020810 mei-1725 mei-1725 http://flybase.net/reports/FBgn0020810.html gene 16-Dec-15 2015_12 FBgn0030261 CG15203 http://flybase.net/reports/FBgn0030261.html protein_coding_gene 0005615=extracellular space "DIGF-1, 144845_at" IPR029277=Single domain Von Willebrand factor type C domain CG15203 16-Dec-15 2015_12 FBgn0029104 anon-21Ab anon-21Ab http://flybase.net/reports/FBgn0029104.html gene X 16-Dec-15 2015_12 FBgn0042221 CG12435 http://flybase.net/reports/FBgn0042221.html FBgn0029671 protein_coding_gene CG18588 16-Dec-15 2015_12 FBgn0051145 CG31145 http://flybase.net/reports/FBgn0051145.html "FBgn0039095, FBgn0039096, FBgn0039097" protein_coding_gene 0004672=protein kinase activity "0006468=protein phosphorylation, 0007476=imaginal disc-derived wing morphogenesis" "0005576=extracellular region, 0005794=Golgi apparatus" "CG13821, CG13820, CG10187" "IPR009581=FAM20, C-terminal, IPR024869=FAM20" CG31145 16-Dec-15 2015_12 ENSDARG00000008573(fam20b) WBGene00010356(H03A11.1) ENSMUSG00000033557(Fam20b) ENSG00000116199(FAM20B) viable FBgn0265882 CR44671 http://flybase.net/reports/FBgn0265882.html non_protein_coding_gene lincRNA.607 CR44671 16-Dec-15 2015_12 FBgn0040475 SH3PX1 SH3PX1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0040475.html FBgn0036033 protein_coding_gene "0005547=phosphatidylinositol-3,4,5-trisphosphate binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding" "0007067=mitotic nuclear division, 0000045=autophagic vacuole assembly, 0006886=intracellular protein transport, 0090389=phagosome-lysosome fusion involved in apoptotic cell clearance, 0071456=cellular response to hypoxia" "0045335=phagocytic vesicle, 0005886=plasma membrane" "CG6757, SH3PX1, p63, dSH3PX1, DSH3PX, DSH3PX1, DmSNX18" "IPR028650=Sorting nexin Lst-4, IPR001452=SH3 domain, IPR019497=Sorting nexin protein, WASP-binding domain, IPR001683=Phox homologous domain, IPR014536=Sorting nexin 9 subfamily" CG6757 16-Dec-15 2015_12 "ENSDARG00000014954(snx33),ENSDARG00000067713(snx18a),ENSDARG00000044246(snx18b)" WBGene00003086(lst-4) "ENSXETG00000015279(TEgg059f08.1),ENSXETG00000023376(snag1)" "ENSMUSG00000032733(Snx33),ENSMUSG00000042364(Snx18)" ENSG00000130340(SNX9) "viable,fertile" FBgn0062664 EP3140 EP3140 http://flybase.net/reports/FBgn0062664.html gene EP(3)3140 16-Dec-15 2015_12 neuroanatomy defective "embryonic/larval central nervous system,neurite | pharate adult stage" FBgn0046681 anon-38B.23 anon-38B.23 http://flybase.net/reports/FBgn0046681.html gene 38B.23 16-Dec-15 2015_12 FBgn0016918 ninaE::Rh2 ninaE::Rh2 http://flybase.net/reports/FBgn0016918.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0030623 PPYR1 Protein phosphatase Y regulator 1 http://flybase.net/reports/FBgn0030623.html FBgn0063314 protein_coding_gene 0032504=multicellular organism reproduction "0005737=cytoplasm, 0005615=extracellular space" "BcDNA:AT19571, CG15031, protein phosphatase Y regulator 1" IPR006861=Hyaluronan/mRNA-binding protein CG15031 16-Dec-15 2015_12 viable FBgn0013494 l(1)9PP12 lethal (1) 9PP12 http://flybase.net/reports/FBgn0013494.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" "embryo,germline clone,embryonic head" FBgn0038950 CG5382 http://flybase.net/reports/FBgn0038950.html protein_coding_gene 0008270=zinc ion binding 0033227=dsRNA transport 0012505=endomembrane system "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG5382 16-Dec-15 2015_12 ENSDARG00000011186(zfpl1) WBGene00021563(Y45G12B.2) ENSXETG00000023095(ZFPL1) ENSMUSG00000024792(Zfpl1) ENSG00000162300(ZFPL1) FBgn0017391 l(1)15Bc lethal (1) 15Bc http://flybase.net/reports/FBgn0017391.html gene 16-Dec-15 2015_12 lethal FBgn0052232 CG32232 http://flybase.net/reports/FBgn0052232.html protein_coding_gene 0000226=microtubule cytoskeleton organization "0000922=spindle pole, 0005815=microtubule organizing center" IPR007259=Gamma-tubulin complex component protein CG32232 16-Dec-15 2015_12 viable FBgn0036782 CG7320 http://flybase.net/reports/FBgn0036782.html protein_coding_gene "IPR008922=Uncharacterised domain, di-copper centre, IPR013788=Hemocyanin/hexamerin, IPR005203=Hemocyanin, C-terminal, IPR005204=Hemocyanin, N-terminal, IPR000896=Hemocyanin/hexamerin middle domain, IPR014756=Immunoglobulin E-set" CG7320 16-Dec-15 2015_12 FBgn0001885 l(2)21Bb lethal (2) 21Bb http://flybase.net/reports/FBgn0001885.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036593 CG13048 http://flybase.net/reports/FBgn0036593.html protein_coding_gene CG13048 16-Dec-15 2015_12 viable FBgn0034294 Muc55B Mucin 55B http://flybase.net/reports/FBgn0034294.html protein_coding_gene 0005201=extracellular matrix structural constituent 0031012=extracellular matrix "CG5765, Muc55B" IPR007931=Protein of unknown function DUF725 CG5765 16-Dec-15 2015_12 "viable,fertile" DRSC21440 K -0.158658669 0.25873674 -0.629524309 -0.243706762 -1.566627092 -0.560463786 FBgn0037000 ZnT77C Zinc transporter 77C http://flybase.net/reports/FBgn0037000.html FBgn0062008 protein_coding_gene "0005385=zinc ion transmembrane transporter activity, 0022883=zinc efflux transmembrane transporter activity" 0071577=zinc II ion transmembrane transport "0005886=plasma membrane, 0016323=basolateral plasma membrane, 0016021=integral component of membrane, 0005622=intracellular" "CG5130, anon-WO0118547.435, cg5130, dZnT77C" "IPR027469=Cation efflux protein transmembrane domain, IPR002524=Cation efflux protein" CG5130 16-Dec-15 2015_12 "viable,fertile" FBgn0044331 936 936 http://flybase.net/reports/FBgn0044331.html gene 0007268=synaptic transmission 16-Dec-15 2015_12 FBgn0046212 CG15841 http://flybase.net/reports/FBgn0046212.html "FBgn0052952, FBtr0080269, FBpp0079853, FBtr0080270, FBpp0079854" protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "unnamed, cg15841, CG32952, CG32952-B" 16-Dec-15 2015_12 FBgn0042635 l(3)S024314b lethal (3) S024314b http://flybase.net/reports/FBgn0042635.html gene "l(3)024314, l(3)S024314, 0243/14" 16-Dec-15 2015_12 "lethal,recessive" FBgn0053430 5SrRNA:CR33430 5SrRNA:CR33430 http://flybase.net/reports/FBgn0053430.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33430 CR33430 16-Dec-15 2015_12 FBgn0267664 CR46002 http://flybase.net/reports/FBgn0267664.html non_protein_coding_gene CR46002 16-Dec-15 2015_12 FBgn0001268 intro introverted http://flybase.net/reports/FBgn0001268.html gene "l(1)Q56, introvert, unnamed, l(1)20Ac, section 23, Q56, l(1)19-88, 23, YT1, R9-13" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" head FBgn0041843 E(Sev-CycE)D50 E(Sev-CycE)D50 http://flybase.net/reports/FBgn0041843.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035620 CG5150 http://flybase.net/reports/FBgn0035620.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR001952=Alkaline phosphatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain" CG5150 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSMUSG00000028766(Alpl),ENSMUSG00000026246(Alppl2),ENSMUSG00000079440(Alpi),ENSMUSG00000036500(Akp3)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0065519 l(2)SH1139 lethal (2) SH1139 http://flybase.net/reports/FBgn0065519.html gene l(2)SH2 1139 16-Dec-15 2015_12 "lethal,recessive" FBgn0005053 fs(1)ne6 female sterile (1) no eggs 6 http://flybase.net/reports/FBgn0005053.html gene "fs(1)ne[6], ne6" 16-Dec-15 2015_12 "female sterile,recessive" "oocyte,dorsal appendage,chorion" FBgn0060388 l(3)S134012a lethal (3) S134012a http://flybase.net/reports/FBgn0060388.html gene 1340/12 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039073 CG4408 http://flybase.net/reports/FBgn0039073.html FBgn0043828 protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "Dmel_CG4408, BEST:GH09055" "IPR009020=Proteinase inhibitor, propeptide, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG4408 16-Dec-15 2015_12 YHR132C(ECM14) "WBGene00020283(T06A4.3),WBGene00011235(R11A5.7),WBGene00021645(Y47G6A.19)" viable FBgn0000317 ck crinkled http://flybase.net/reports/FBgn0000317.html "FBgn0015260, FBgn0015868, FBgn0020027, FBgn0044341" protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled, 0030898=actin-dependent ATPase activity, 0005524=ATP binding, 0032027=myosin light chain binding, 0045296=cadherin binding, 0003779=actin binding" "0007423=sensory organ development, 0035317=imaginal disc-derived wing hair organization, 0030048=actin filament-based movement, 0007605=sensory perception of sound, 0048800=antennal morphogenesis, 0032529=follicle cell microvillus organization, 0035293=chitin-based larval cuticle pattern formation, 0008407=chaeta morphogenesis, 0008586=imaginal disc-derived wing vein morphogenesis, 0007015=actin filament organization, 0007469=antennal development" "0031477=myosin VII complex, 0035182=female germline ring canal outer rim, 0031941=filamentous actin, 0070825=micropyle, 0005902=microvillus, 0045179=apical cortex, 0005938=cell cortex, 0016459=myosin complex, 0045180=basal cortex, 0016461=unconventional myosin complex, 0005737=cytoplasm" "l(2)br27, l(1)35Ca, l(2)07130, Myo7A, Crinkled, myoVIIA, transcription unit D, myosin 7a, 53D10S, D2, br27, myosin 7a heavy chain, CG7595, Dro35B, l(2)35Ca, Mhc35BC, lethal group D2, Myosin heavy chain at 35BC, Dm 35B, ESTS:53D10S, stch, BG:DS00929.11, myosin VIIA, myosin-VII, DmVIIA, MyoVIIA, DMyoVIIa, stubby chaetae, lethal 27 in the black-reduced region, ck/MyoVIIA, D, mysoin VIIa, l35Ca, DmVIIa, myosin VIIa, stc, anon-35Bb, myosin VII, DM7a" "IPR000299=FERM domain, IPR029071=Ubiquitin-related domain, IPR001452=SH3 domain, IPR001609=Myosin head, motor domain, IPR000857=MyTH4 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000048=IQ motif, EF-hand binding site, IPR019748=FERM central domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle" CG7595 16-Dec-15 2015_12 ENSDARG00000044632(LOC556141) WBGene00002039(hum-6) ENSXETG00000007165() ENSMUSG00000030761(Myo7a) ENSG00000137474(MYO7A) "viable,fertile,auditory perception defective,visible,recessive,partially lethal - majority die,lethal,lethal - all die before end of larval stage,some die during larval stage,sterile,lethal - all die before end of embryonic stage,some die during embryonic stage" "Johnston's organ & scolopidium,Johnston's organ & dendritic cap cell,wing hair,supernumerary,dorsal fine hair,ocellar bristle,arista,ectopic,macrochaeta,microchaeta,trichogen cell,wing,male genitalia" FBgn0051644 CG31644 http://flybase.net/reports/FBgn0051644.html FBgn0047339 protein_coding_gene 0004129=cytochrome-c oxidase activity BcDNA:AT20031 IPR004204=Cytochrome c oxidase subunit 6C CG31644 16-Dec-15 2015_12 viable FBgn0003182 Q Queer wing http://flybase.net/reports/FBgn0003182.html gene 16-Dec-15 2015_12 "wing,abdominal tergite marginal bristle" FBgn0283434 CG46277 http://flybase.net/reports/FBgn0283434.html protein_coding_gene CG46277 16-Dec-15 2015_12 FBgn0264374 CR43826 http://flybase.net/reports/FBgn0264374.html non_protein_coding_gene CR43826 16-Dec-15 2015_12 FBgn0259749 mmy mummy http://flybase.net/reports/FBgn0259749.html "FBgn0026258, FBgn0086705, FBgn0027501, FBgn0002776, FBgn0044627, FBgn0042651" protein_coding_gene 0003977=UDP-N-acetylglucosamine diphosphorylase activity "0040003=chitin-based cuticle development, 0007424=open tracheal system development, 0007413=axonal fasciculation, 0030198=extracellular matrix organization, 0007417=central nervous system development, 0006035=cuticle chitin biosynthetic process, 0007391=dorsal closure, 0001838=embryonic epithelial tube formation, 0035151=regulation of tube size, open tracheal system, 0008362=chitin-based embryonic cuticle biosynthetic process" "Mummy, cabrio, cystic, UDP-GlcNAc pyrophosphorylase, LD44264, cyst, BcDNA:LD24639, mummy, anon-WO0140519.242, CG9535, cys, cao, l(2)k13717b, mum, Cystic" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR002618=UTP--glucose-1-phosphate uridylyltransferase family" CG9535 16-Dec-15 2015_12 "ENSDARG00000052170(uap1),ENSDARG00000013082(uap1l1)" YDL103C(QRI1) "WBGene00007965(C36A4.4),WBGene00019439(K06B9.2)" ENSXETG00000010459(Uap1) "ENSMUSG00000026670(Uap1),ENSMUSG00000026956(Uap1l1)" "ENSG00000117143(UAP1),ENSG00000197355(UAP1L1)" FBgn0063380 snoRNA:U31:54Eb snoRNA:U31:54Eb http://flybase.net/reports/FBgn0063380.html snoRNA_gene "U31snoRNA, CR32897" CR32897 16-Dec-15 2015_12 FBgn0067327 A23 A23 http://flybase.net/reports/FBgn0067327.html gene 16-Dec-15 2015_12 "eye color defective,lethal" pigment cell FBgn0015522 olf186-M olf186-M http://flybase.net/reports/FBgn0015522.html protein_coding_gene 0005102=receptor binding CG14489 IPR029325=IP3R-interacting domain CG14489 16-Dec-15 2015_12 viable FBgn0002814 ms(1)V73 male sterile (1) V73 http://flybase.net/reports/FBgn0002814.html gene 16-Dec-15 2015_12 male sterile FBgn0017464 TfIIH-45 Transcription factor IIH-45kD http://flybase.net/reports/FBgn0017464.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TFIIH, TfIIH" 16-Dec-15 2015_12 FBgn0035926 CG5804 http://flybase.net/reports/FBgn0035926.html FBgn0047183 protein_coding_gene "0000062=fatty-acyl-CoA binding, 0050809=diazepam binding, 0004857=enzyme inhibitor activity" 0042049=cellular acyl-CoA homeostasis BcDNA:RE05521 "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000582=Acyl-CoA-binding protein, ACBP" CG5804 16-Dec-15 2015_12 viable FBgn0031550 Che-13 Che-13 ortholog (C. elegans) http://flybase.net/reports/FBgn0031550.html protein_coding_gene "0042384=cilium assembly, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0042981=regulation of apoptotic process, 0060271=cilium morphogenesis, 0006915=apoptotic process" "0005929=cilium, 0036064=ciliary basal body, 0030992=intraciliary transport particle B" "che-13, IFT55, CG8853, Hippi, IFT57, CHE-13" IPR019530=Intra-flagellar transport protein 57 CG8853 16-Dec-15 2015_12 ENSDARG00000021022(ift57) WBGene00000492(che-13) ENSXETG00000026185(esrrbl1) ENSMUSG00000032965(Ift57) ENSG00000114446(IFT57) FBgn0024861 l(3)96Ba lethal (3) 96Ba http://flybase.net/reports/FBgn0024861.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267009 CR45453 http://flybase.net/reports/FBgn0267009.html non_protein_coding_gene CR45453 16-Dec-15 2015_12 FBgn0065397 l(2)SH1612 lethal (2) SH1612 http://flybase.net/reports/FBgn0065397.html gene l(2)SH2 1612 16-Dec-15 2015_12 "lethal,recessive" FBgn0086603 snoRNA:Or-CD2 http://flybase.net/reports/FBgn0086603.html "FBgn0053636, FBgn0065065, FBgn0082920" snoRNA_gene 0005730=nucleolus "Dm-461, snoR461, DmOr_cd2 snoRNA, chr2R:4608869..4608988, snoRNA:Or-cd2, CR33636, DmOr_cd2(SnoR461), Or-CD2, snoRNA:461, orphan-CD2" CR33636 16-Dec-15 2015_12 FBgn0014313 l(3)ry111 lethal (3) ry111 http://flybase.net/reports/FBgn0014313.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051389 CG31389 http://flybase.net/reports/FBgn0051389.html protein_coding_gene 0046331=lateral inhibition 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible,body color defective" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC12860 E -0.078660134 0.317929658 1.667566496 -0.839669311 -0.417453656 0.525698745 FBgn0065389 l(2)SH1631 lethal (2) SH1631 http://flybase.net/reports/FBgn0065389.html gene l(2)SH2 1631 16-Dec-15 2015_12 "lethal,recessive" FBgn0000193 Bl Bristle http://flybase.net/reports/FBgn0000193.html gene "Sy, Stubby-31l, bl, Sy[31l]" 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" "macrochaeta,eye" FBgn0086212 flt-2 http://flybase.net/reports/FBgn0086212.html gene 16-Dec-15 2015_12 FBgn0084023 CG41462 http://flybase.net/reports/FBgn0084023.html FBan0041462 protein_coding_gene 16-Dec-15 2015_12 FBgn0265902 CR44691 http://flybase.net/reports/FBgn0265902.html non_protein_coding_gene lincRNA.1010 CR44691 16-Dec-15 2015_12 FBgn0266061 Su(var)301 http://flybase.net/reports/FBgn0266061.html gene 301 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0005270 l(3)SG90 lethal (3) SG90 http://flybase.net/reports/FBgn0005270.html gene l(3)K60 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0004649 yl yolkless http://flybase.net/reports/FBgn0004649.html "FBgn0000732, FBgn0004043" protein_coding_gene "0008196=vitellogenin receptor activity, 0005509=calcium ion binding" "0048477=oogenesis, 0007296=vitellogenesis" "0030135=coated vesicle, 0031410=cytoplasmic vesicle" "fs(1)A148, CT3114, fs(1)L193, Yl, fs(1)L186, fs(1)L196, fs(1)148, YL, fs(1)M25, Dm Yolkless, LR13, fs(1)M205, fs(1)L211, fs(1)5, DmYPR, CG1372, fs(1)K184, fs(1)yolkless, Yolkless, YP receptor, fs(1)yl" "IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR011042=Six-bladed beta-propeller, TolB-like, IPR001881=EGF-like calcium-binding domain, IPR000033=LDLR class B repeat, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site" CG1372 16-Dec-15 2015_12 WBGene00008779(F14B4.1) oogenesis stage && adult stage | female ovary

"female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile soma-dependent,viable" "chorion,yolk granule,adult hemolymph,female,egg,maternal effect,stage S10 oocyte,stage S13 oocyte,stage S14 oocyte,coated pit,coated vesicle,stage S10 oocyte & clathrin-coated vesicle" FBgn0004608 fur fused rhabdomeres http://flybase.net/reports/FBgn0004608.html gene 16-Dec-15 2015_12 "neurophysiology defective,wild-type" "rhabdomere,optic lobe,retina,lamina,medulla" FBgn0065929 l(2)SH0139 lethal (2) SH0139 http://flybase.net/reports/FBgn0065929.html gene l(2)SH2 0139 16-Dec-15 2015_12 "lethal,recessive" FBgn0039805 Cpr100A Cuticular protein 100A http://flybase.net/reports/FBgn0039805.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr100A, CG12045" IPR000618=Insect cuticle protein CG12045 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0004913 Gnf1 Germ line transcription factor 1 http://flybase.net/reports/FBgn0004913.html "FBgn0010351, FBgn0020380, FBgn0025510" protein_coding_gene "0005524=ATP binding, 0003689=DNA clamp loader activity, 0003677=DNA binding" "0046331=lateral inhibition, 0006260=DNA replication, 0048813=dendrite morphogenesis, 0006281=DNA repair, 0022008=neurogenesis" "0005875=microtubule associated complex, 0005663=DNA replication factor C complex, 0005634=nucleus" "ONF-CAACAA, DmRFC1, gnf1, RFC1, Gtf1, rfc1, GTF-1, CG1119, Replication factor C 140kD subunit, Replication-factor-C 140kD subunit, dRF-Cp140, RfC140, RF-C 140, RfC, Gnf-1, dRFC140, gtf1, germline transcription factor, RFC" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR012178=Replication factor C subunit 1, IPR001357=BRCT domain, IPR013725=DNA replication factor RFC1, C-terminal, IPR003593=AAA+ ATPase domain, IPR008921=DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal" CG1119 16-Dec-15 2015_12 ENSDARG00000005974(zgc:66453) YOR217W(RFC1) WBGene00004337(rfc-1) ENSMUSG00000029191(Rfc1) ENSG00000035928(RFC1) "lethal,recessive,neuroanatomy defective,viable,visible" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum" DRSC12351 IE -0.717906792 -1.755126068 -1.760259825 -1.436493771 0.746828196 0.275440347 FBgn0085561 CG41229 http://flybase.net/reports/FBgn0085561.html FBan0041229 protein_coding_gene 16-Dec-15 2015_12 FBgn0003052 pe petit http://flybase.net/reports/FBgn0003052.html gene 16-Dec-15 2015_12 "female fertile,reduced,visible,viable" eye FBgn0262622 CR43146 http://flybase.net/reports/FBgn0262622.html non_protein_coding_gene "lincRNA.537, CG43146" CR43146 16-Dec-15 2015_12 FBgn0065481 l(2)SH1281 lethal (2) SH1281 http://flybase.net/reports/FBgn0065481.html gene l(2)SH2 1281 16-Dec-15 2015_12 "lethal,recessive" FBgn0050135 CG30135 http://flybase.net/reports/FBgn0050135.html protein_coding_gene 16-Dec-15 2015_12 FBgn0259527 B0010 http://flybase.net/reports/FBgn0259527.html gene 16-Dec-15 2015_12 visible wing FBgn0001932 l(2)25Ee lethal (2) 25Ee http://flybase.net/reports/FBgn0001932.html gene "l(2)gdh9, jf29, l(2)jf29, l(2)gdh-9" 16-Dec-15 2015_12 "lethal,recessive" FBgn0011864 tRNA:G3:35Bc transfer RNA:gly3:35Bc http://flybase.net/reports/FBgn0011864.html "FBgn0003779, FBgn0051982, FBgn0060220" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033462=GGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:G:GCC:AE002690-e, tRNA:gly3:35Bc, CR31982, BG:DS04641.5, tRNA[Gly-GCC], AE002690.trna17-GlyGCC, chr2L.trna26-GlyGCC" CR31982 16-Dec-15 2015_12 FBgn0036627 Gagr Gag-related http://flybase.net/reports/FBgn0036627.html protein_coding_gene "CG4680, Gag related protein, Grp" CG4680 16-Dec-15 2015_12 FBgn0023059 l(1)2Ec lethal (1) 2Ec http://flybase.net/reports/FBgn0023059.html gene D3/36.6 16-Dec-15 2015_12 "lethal,recessive" FBgn0086884 Wed http://flybase.net/reports/FBgn0086884.html gene 16-Dec-15 2015_12 "female sterile,recessive,male fertile,viable,female,poor,male,visible,dominant" "eye,ommatidium" FBgn0052673 Rab9E Rab at 9E http://flybase.net/reports/FBgn0052673.html FBgn0046863 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction, 0015031=protein transport" 0031982=vesicle "Rab GTPase 9E, CG32673, unnamed, anon-AE003451.2" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG32673 16-Dec-15 2015_12 FBgn0033724 CG8501 http://flybase.net/reports/FBgn0033724.html protein_coding_gene CG8501 16-Dec-15 2015_12 FBgn0038832 CG15695 http://flybase.net/reports/FBgn0038832.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi7300665, gi21356013" "IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR004245=Protein of unknown function DUF229" CG15695 16-Dec-15 2015_12 viable FBgn0062663 EP3186 EP3186 http://flybase.net/reports/FBgn0062663.html gene EP(3)3186 16-Dec-15 2015_12 FBgn0265425 CR44337 http://flybase.net/reports/FBgn0265425.html non_protein_coding_gene CR44337 16-Dec-15 2015_12 FBgn0036019 Or67b Odorant receptor 67b http://flybase.net/reports/FBgn0036019.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "CG14176, 67B.2, 67b" "IPR004117=Olfactory receptor, Drosophila" CG14176 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0020764 Alas Aminolevulinate synthase http://flybase.net/reports/FBgn0020764.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0003870=5-aminolevulinate synthase activity" "0040003=chitin-based cuticle development, 0006783=heme biosynthetic process" "0005759=mitochondrial matrix, 0005739=mitochondrion" "ALAS, alas, delta-Aminolevulinate synthase, CG3017, delta-aminolevulinate synthase, Alas/50-Aminolevulinate synthase" "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR004839=Aminotransferase, class I/classII, IPR015424=Pyridoxal phosphate-dependent transferase, IPR010961=Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase" CG3017 16-Dec-15 2015_12 ENSDARG00000038643(alas2) YDR232W(HEM1) "ENSXETG00000010814(alas1),ENSXETG00000022017(alas2)" "ENSMUSG00000032786(Alas1),ENSMUSG00000025270(Alas2)" "ENSG00000023330(ALAS1),ENSG00000158578(ALAS2)" "small body,partially lethal - majority die,some die during pupal stage,lethal" "embryonic/first instar larval cuticle,embryonic/larval tracheal system,procuticle" FBgn0035951 CG5068 http://flybase.net/reports/FBgn0035951.html protein_coding_gene 0052689=carboxylic ester hydrolase activity 0006482=protein demethylation "IPR029058=Alpha/Beta hydrolase fold, IPR016812=Protein phosphatase methylesterase, eukaryotic, IPR000073=Alpha/beta hydrolase fold-1, IPR000639=Epoxide hydrolase-like" CG5068 16-Dec-15 2015_12 ENSDARG00000009771(ppme1) YHR075C(PPE1) WBGene00007188(B0464.9) ENSXETG00000012561(PPME1) ENSMUSG00000030718(Ppme1) ENSG00000214517(PPME1) viable FBgn0014974 l(1)13Fd lethal (1) 13Fd http://flybase.net/reports/FBgn0014974.html gene "IX, l(1)IX" 16-Dec-15 2015_12 "wild-type,lethal,recessive" FBgn0060646 l(3)S083902b lethal (3) S083902b http://flybase.net/reports/FBgn0060646.html gene 0839/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0264505 CR43904 http://flybase.net/reports/FBgn0264505.html non_protein_coding_gene CR43904 16-Dec-15 2015_12 FBgn0033952 Adgf-E Adenosine deaminase-related growth factor E http://flybase.net/reports/FBgn0033952.html protein_coding_gene "0004000=adenosine deaminase activity, 0008083=growth factor activity" "0043103=hypoxanthine salvage, 0046103=inosine biosynthetic process, 0008283=cell proliferation, 0006154=adenosine catabolic process" "0005615=extracellular space, 0005829=cytosol, 0005576=extracellular region" "adgfe, ADGF-E, CG10143" "IPR006331=Adenosine deaminase-related growth factor, IPR013659=Adenosine/AMP deaminase N-terminal, IPR001365=Adenosine/AMP deaminase domain" CG10143 16-Dec-15 2015_12 "ENSDARG00000051744,ENSDARG00000051746(cecr1a),ENSDARG00000015623(cecr1b)" ENSXETG00000000874(CECR1) ENSG00000093072(CECR1) FBgn0053651 CG33651 http://flybase.net/reports/FBgn0053651.html FBgn0025999 protein_coding_gene "anon-EST:Liang-1.3, clone 1.3" 16-Dec-15 2015_12 FBgn0264296 CG43774 http://flybase.net/reports/FBgn0264296.html FBgn0031581 protein_coding_gene CG10039 CG43774 16-Dec-15 2015_12 viable FBgn0011904 tRNA:K5:84ABa transfer RNA:lys5:84AB http://flybase.net/reports/FBgn0011904.html "FBgn0003793, FBgn0011901, FBgn0051486, FBgn0060176" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033443=AAA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K:TTT:AE002699-a, Lys-5, lys5:84ABa, AE002699.trna4-LysTTT, CR31486, BG:DS00276.1, tRNA:lys5:84AB, lys-tRNA-5, chr3R.trna77-LysTTT, tRNA:K5" CR31486 16-Dec-15 2015_12 FBgn0024911 anon-16Fa anon-16Fa http://flybase.net/reports/FBgn0024911.html gene F-b 16-Dec-15 2015_12 FBgn0027783 SMC2 Structural maintenance of chromosomes 2 http://flybase.net/reports/FBgn0027783.html protein_coding_gene "0046982=protein heterodimerization activity, 0005524=ATP binding, 0016887=ATPase activity, 0003677=DNA binding, 0003682=chromatin binding" "0022008=neurogenesis, 0007076=mitotic chromosome condensation, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0007062=sister chromatid cohesion" "0008278=cohesin complex, 0005737=cytoplasm, 0000785=chromatin, 0005875=microtubule associated complex, 0000796=condensin complex, 0000793=condensed chromosome" "Smc2, CG10212, DmSMC2, AAF58197, SMC2, dSMC2, smc-2" "IPR003395=RecF/RecN/SMC, N-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027120=Structural maintenance of chromosomes Smc2, IPR024704=Structural maintenance of chromosomes protein, IPR010935=SMCs flexible hinge" CG10212 16-Dec-15 2015_12 ENSDARG00000017744(smc2) YFR031C(SMC2) WBGene00003367(mix-1) ENSXETG00000010209(SMC2) ENSMUSG00000028312(Smc2) ENSG00000136824(SMC2) "viable,fertile,enhancer of variegation,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval brain,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0067336 mir-84 mir-84 http://flybase.net/reports/FBgn0067336.html miRNA_gene miR-84 16-Dec-15 2015_12 FBgn0267795 CG32138 http://flybase.net/reports/FBgn0267795.html "FBgn0052138, FBgn0036407, FBgn0036408, FBgn0046339, FBgn0264718" protein_coding_gene "0003779=actin binding, 0017048=Rho GTPase binding" "0048812=neuron projection morphogenesis, 0030036=actin cytoskeleton organization" "CG43986, Q9VUC5_DROME, CG13485, Q9VUC6_DROME, CG6807, anon-WO0172774.98" "IPR014767=Diaphanous autoregulatory (DAD) domain, IPR010472=Formin, FH3 domain, IPR010473=Formin, GTPase-binding domain, IPR015425=Formin, FH2 domain, IPR014768=Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR016024=Armadillo-type fold" CG32138 16-Dec-15 2015_12 "ENSDARG00000055713(LOC557062),ENSDARG00000012586" YNL271C(BNI1) WBGene00021698(frl-1) "ENSXETG00000021703(FMNL2),ENSXETG00000000581(FMNL3),ENSXETG00000003221(BC082512.1)" "ENSMUSG00000036053(Fmnl2),ENSMUSG00000023008(Fmnl3),ENSMUSG00000055805(Fmnl1)" "ENSG00000157827(FMNL2),ENSG00000161791(FMNL3),ENSG00000184922(FMNL1)" FBgn0038436 Gyc-89Db Guanylyl cyclase at 89Db http://flybase.net/reports/FBgn0038436.html protein_coding_gene "0020037=heme binding, 0046982=protein heterodimerization activity, 0004383=guanylate cyclase activity" "0055093=response to hyperoxia, 0035556=intracellular signal transduction, 0006182=cGMP biosynthetic process, 0001666=response to hypoxia, 0000302=response to reactive oxygen species" "0008074=guanylate cyclase complex, soluble" CG14886 "IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR024096=NO signalling/Golgi transport ligand-binding domain, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR011645=Haem NO binding associated, IPR011644=Heme-NO binding" CG14886 16-Dec-15 2015_12 "stress response defective,taste perception defective,viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053448 5SrRNA:CR33448 5SrRNA:CR33448 http://flybase.net/reports/FBgn0053448.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33448 CR33448 16-Dec-15 2015_12 FBgn0019849 anon-XV anon-XV http://flybase.net/reports/FBgn0019849.html gene XV 16-Dec-15 2015_12 FBgn0262551 Mod(GMroX1)143 http://flybase.net/reports/FBgn0262551.html gene 16-Dec-15 2015_12 FBgn0260658 CG42541 http://flybase.net/reports/FBgn0260658.html "FBgn0029682, FBgn0029683, FBgn0062938, FBgn0029684, FBgn0052776" protein_coding_gene 0005525=GTP binding "0007264=small GTPase mediated signal transduction, 0006909=phagocytosis" 0016020=membrane "BcDNA:RH43809, CG32776, CG16828, CG15240, CG16829" "IPR020849=Small GTPase superfamily, Ras type, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG42541 16-Dec-15 2015_12 WBGene00013124(Y52B11A.4) FBgn0004970 l(1)4Ea lethal (1) 4Ea http://flybase.net/reports/FBgn0004970.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267635 CR45973 http://flybase.net/reports/FBgn0267635.html non_protein_coding_gene CR45973 16-Dec-15 2015_12 FBgn0010385 Def Defensin http://flybase.net/reports/FBgn0010385.html protein_coding_gene "0006959=humoral immune response, 0009617=response to bacterium, 0019731=antibacterial humoral response, 0050830=defense response to Gram-positive bacterium, 0042742=defense response to bacterium, 0006965=positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" 0005615=extracellular space "143607_at, def, defensin, CG1385, DIM 26, Defensin precursor, DEF" "IPR003614=Knottin, scorpion toxin-like, IPR001542=Defensin, invertebrate/fungal" CG1385 16-Dec-15 2015_12 " larval stage , adult stage " " embryonic/larval fat body

, adult fat body

" viable FBgn0267108 CR45548 http://flybase.net/reports/FBgn0267108.html pseudogene_attribute CR45548 16-Dec-15 2015_12 FBgn0010118 l(1)16Fe lethal (1) 16Fe http://flybase.net/reports/FBgn0010118.html gene HL-VI 16-Dec-15 2015_12 "lethal,polyphasic,recessive,neurophysiology defective" "wing,leg,adult somatic muscle" FBgn0053556 form3 formin 3 http://flybase.net/reports/FBgn0053556.html "FBpp0076619, FBtr0076911, FBpp0076620, FBan0032384, FBan0014824, FBgn0035738, FBgn0035739, FBgn0035740, FBgn0052384" protein_coding_gene 0003779=actin binding "0035147=branch fusion, open tracheal system, 0016043=cellular component organization, 0007424=open tracheal system development" "formin 3, CG32384, CG14824, Form3, CG18138, CG8633, formin3, CG33556, ah1644, INF2, formin/DIA-like" "IPR010472=Formin, FH3 domain, IPR014768=Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425=Formin, FH2 domain, IPR016024=Armadillo-type fold" CG33556 16-Dec-15 2015_12 WBGene00019030(inft-1) ENSMUSG00000041842(Fhdc1) ENSG00000203485(INF2) "lethal,viable,recessive,neuroanatomy defective,oxidative stress response defective,fertile" "presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,dorsal trunk primordium,ventral nerve cord commissure,longitudinal connective,ventral nerve cord" FBgn0022315 l(1)D39.5 lethal (1) D39.5 http://flybase.net/reports/FBgn0022315.html gene D39.5 16-Dec-15 2015_12 "lethal,recessive" FBgn0069138 mcl(3)Z5839 mcl(3)Z5839 http://flybase.net/reports/FBgn0069138.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0264741 CG43999 http://flybase.net/reports/FBgn0264741.html "FBgn0039127, FBgn0063768" protein_coding_gene "CR43999, CG13602, BcDNA:AT03227" IPR010754=Optic atrophy 3-like CG43999 16-Dec-15 2015_12 FBgn0036777 CG7341 http://flybase.net/reports/FBgn0036777.html protein_coding_gene CG7341 16-Dec-15 2015_12 FBgn0003368 sfc stiff chaetae http://flybase.net/reports/FBgn0003368.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile" macrochaeta FBgn0032452 CG15484 http://flybase.net/reports/FBgn0032452.html protein_coding_gene CG15484 16-Dec-15 2015_12 viable FBgn0052203 Spn75F Serpin 75F http://flybase.net/reports/FBgn0052203.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0046331=lateral inhibition, 0032504=multicellular organism reproduction" 0005615=extracellular space "6h1, BG642378(6h1), BG642378, CG32203" "IPR023796=Serpin domain, IPR000215=Serpin family" CG32203 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0019685 mbr mushroom bodies reduced http://flybase.net/reports/FBgn0019685.html gene 0016319=mushroom body development 16-Dec-15 2015_12 "partially lethal - majority die,male sterile,locomotor behavior defective,female limited" "adult brain,lobula,ellipsoid body,nodulus,calyx of larval mushroom body,calyx of adult mushroom body,lobe system of adult mushroom body" FBgn0002689 mbmC mushroom body miniature C http://flybase.net/reports/FBgn0002689.html gene 0016319=mushroom body development "olfactory pathway, mbmC[N28], mushroom-body-miniature-C, opa" 16-Dec-15 2015_12 "behavior defective,locomotor behavior defective,partially lethal - majority die,female limited" "ellipsoid body,nodulus,antennal lobe,calyx of larval mushroom body,lobe system of adult mushroom body,calyx of adult mushroom body" FBgn0043025 Adgf-A2 Adenosine deaminase-related growth factor A2 http://flybase.net/reports/FBgn0043025.html "FBgn0052178, FBgn0065024" protein_coding_gene "0004000=adenosine deaminase activity, 0008083=growth factor activity" "0043103=hypoxanthine salvage, 0046103=inosine biosynthetic process, 0008283=cell proliferation, 0006154=adenosine catabolic process, 0007286=spermatid development" "0005615=extracellular space, 0005829=cytosol, 0016021=integral component of membrane, 0016020=membrane" "Male-specific insect derived growth factor, ADGF-A2, Msi, BcDNA:AT05468, male-specific-imaginal-disc-growth-factor, male-specific IDGF, CG32178, MSI" "IPR006331=Adenosine deaminase-related growth factor, IPR001365=Adenosine/AMP deaminase domain, IPR013659=Adenosine/AMP deaminase N-terminal" CG32178 16-Dec-15 2015_12 ENSXETG00000000874(CECR1) " pupal stage , adult stage | male , spermatogenesis && adult stage " " testis

, spermatocyte

" spermatogenesis && adult stage " spermatid

, spermatozoon

, spermatocyte

" viable FBgn0259563 B2016 http://flybase.net/reports/FBgn0259563.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0029000 ms(3)mntr male sterile minotaurus http://flybase.net/reports/FBgn0029000.html gene 16-Dec-15 2015_12 FBgn0069167 mcl(3)Z1345 mcl(3)Z1345 http://flybase.net/reports/FBgn0069167.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0035083 Tina-1 Troponin C-akin-1 http://flybase.net/reports/FBgn0035083.html "FBgn0040500, FBtr0072411, FBpp0072317" protein_coding_gene 0008307=structural constituent of muscle 0007507=heart development "CG2803, BEST:GM14784" "IPR013024=Butirosin biosynthesis, BtrG-like, IPR009288=Gamma-glutamylcyclotransferase, AIG2-like" CG2803 16-Dec-15 2015_12 "ENSDARG00000070579(zgc:162208),ENSDARG00000038248(zgc:92115),ENSDARG00000070581(zgc:154024)" WBGene00023489(F42A10.9) ENSXETG00000024582(A2LD1) ENSMUSG00000041625(A2ld1) ENSG00000134864(A2LD1) viable FBgn0013649 ms(2)ry5 ms(2)ry5 http://flybase.net/reports/FBgn0013649.html gene "ms(2)5, unnamed" 16-Dec-15 2015_12 male sterile FBgn0038601 CG18600 http://flybase.net/reports/FBgn0038601.html FBgn0027075 protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0006351=transcription, DNA-templated" 0005634=nucleus "BEST:CK01205, CK01205" "IPR009668=RNA polymerase I associated factor, A49-like" CG18600 16-Dec-15 2015_12 viable embryonic/larval hemocyte | third instar larval stage FBgn0001081 fmb fused mushroom bodies http://flybase.net/reports/FBgn0001081.html gene 0016319=mushroom body development fum 16-Dec-15 2015_12 "mushroom body beta-lobe,mushroom body gamma-lobe,ellipsoid body" FBgn0051338 CR31338 http://flybase.net/reports/FBgn0051338.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0086445 l(2)37Cd lethal (2) 37Cd http://flybase.net/reports/FBgn0086445.html "FBgn0002032, FBgn0032760" protein_coding_gene 0006909=phagocytosis "Cd, CG10563" "IPR019136=Transcription factor IIIC, subunit 5" CG10563 16-Dec-15 2015_12 WBGene00011368(T02C12.3) ENSXETG00000006264(GTF3C5) ENSMUSG00000026816(Gtf3c5) ENSG00000148308(GTF3C5) FBgn0010737 l(3)01107 lethal (3) 01107 http://flybase.net/reports/FBgn0010737.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015300 Ssl Suppressor of Stellate-like http://flybase.net/reports/FBgn0015300.html "FBgn0014036, FBgn0045134" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0019887=protein kinase regulator activity" 0006468=protein phosphorylation 0005956=protein kinase CK2 complex "CKIIb1, regulatory subunit of protein kinase CK2, DmCK2betates, Su(Ste)-like, betaCK2tes, CG13591, SSL, CK2betates, NEST:bs30a09, Su(Ste)l" "IPR000704=Casein kinase II, regulatory subunit, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG13591 16-Dec-15 2015_12 "lethal,viable" DRSC04657 K -0.09231576 0.412297162 -1.28937673 -0.339171567 2.5572306 2.199465422 FBgn0067749 l(1)G0206 lethal (1) G0206 http://flybase.net/reports/FBgn0067749.html gene 16-Dec-15 2015_12 FBgn0085773 CR40766 http://flybase.net/reports/FBgn0085773.html FBan0040766 rRNA_gene CR40766 16-Dec-15 2015_12 FBgn0266942 CR45393 http://flybase.net/reports/FBgn0266942.html non_protein_coding_gene CR45393 16-Dec-15 2015_12 FBgn0027610 Dic1 Dicarboxylate carrier 1 http://flybase.net/reports/FBgn0027610.html protein_coding_gene "0015117=thiosulfate transmembrane transporter activity, 0015131=oxaloacetate transmembrane transporter activity, 0015141=succinate transmembrane transporter activity, 0005315=inorganic phosphate transmembrane transporter activity, 0022857=transmembrane transporter activity, 0015140=malate transmembrane transporter activity, 0005310=dicarboxylic acid transmembrane transporter activity, 0015116=sulfate transmembrane transporter activity" "0008272=sulfate transport, 0071423=malate transmembrane transport, 0015709=thiosulfate transport, 0015729=oxaloacetate transport, 0035435=phosphate ion transmembrane transport, 0071422=succinate transmembrane transport, 0006839=mitochondrial transport" "0031966=mitochondrial membrane, 0005739=mitochondrion" "DmDic1p, BcDNA:GH02431, CG8790" "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG8790 16-Dec-15 2015_12 ENSDARG00000025074(slc25a10) YLR348C(DIC1) WBGene00019656(K11G12.5) ENSXETG00000019705(slc25a10) ENSMUSG00000025792(Slc25a10) ENSG00000183048(MRPL12) viable FBgn0264663 sprout sprout http://flybase.net/reports/FBgn0264663.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "decreased cell growth,somatic clone" "terminal tracheal cell,eye,somatic clone" FBgn0045469 Gr93c Gustatory receptor 93c http://flybase.net/reports/FBgn0045469.html "FBgn0038907, FBgn0041227, FBgn0051173" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 93F.3, CG31173, Gr93F3, CG13411, GR93c, GR93F.3, 93F.3" IPR013604=7TM chemoreceptor CG31173 16-Dec-15 2015_12 viable FBgn0260122 2L0445 http://flybase.net/reports/FBgn0260122.html gene 16-Dec-15 2015_12 viable "embryonic/larval dorsal trunk,somatic clone,embryonic/larval transverse connective,embryonic/larval tracheal system" FBgn0029837 Tsp5D Tetraspanin 5D http://flybase.net/reports/FBgn0029837.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp5D, CG4690, tsp5D" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG4690 16-Dec-15 2015_12 "ENSDARG00000025299(tspan9),ENSDARG00000045706(zgc:91880),ENSDARG00000070200(LOC100149209),ENSDARG00000031991,ENSDARG00000070391(zgc:163023)" "ENSXETG00000002879(),ENSXETG00000019055(TSPAN4),ENSXETG00000016985(TSPAN9),ENSXETG00000015353(CD53)" "ENSMUSG00000030352(Tspan9),ENSMUSG00000025511(Tspan4),ENSMUSG00000040747(Cd53)" "ENSG00000011105(TSPAN9),ENSG00000214063(TSPAN4),ENSG00000143119(CD53)" viable FBgn0264511 CR43910 http://flybase.net/reports/FBgn0264511.html non_protein_coding_gene CR43910 16-Dec-15 2015_12 FBgn0030906 CG15063 http://flybase.net/reports/FBgn0030906.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266995 CR45446 http://flybase.net/reports/FBgn0266995.html non_protein_coding_gene CR45446 16-Dec-15 2015_12 FBgn0037962 CG6971 http://flybase.net/reports/FBgn0037962.html FBgn0044561 protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex "anon-WO0140519.67, DNALI1" IPR019347=Axonemal dynein light chain CG6971 16-Dec-15 2015_12 ENSDARG00000069815(zgc:171595) WBGene00018307(F41G4.1) ENSXETG00000002166(dnali1) ENSMUSG00000042707(Dnali1) ENSG00000163879(DNALI1) viable FBgn0005186 l(2)S32 lethal of Seto 32 http://flybase.net/reports/FBgn0005186.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg,pupa" FBgn0039356 CG5039 http://flybase.net/reports/FBgn0039356.html FBgn0063145 protein_coding_gene BcDNA:LD35121 CG5039 16-Dec-15 2015_12 "viable,fertile" FBgn0052382 sphinx2 sphinx2 http://flybase.net/reports/FBgn0052382.html FBgn0035783 protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0050829=defense response to Gram-negative bacterium, 0050830=defense response to Gram-positive bacterium, 0045087=innate immune response, 0045752=positive regulation of Toll signaling pathway, 0006508=proteolysis, 0050832=defense response to fungus" 0005576=extracellular region "SPH194, CG8555, Sphinx2, CG32382" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG32382 16-Dec-15 2015_12 "immune response defective,viable" FBgn0065848 l(2)SH0310 lethal (2) SH0310 http://flybase.net/reports/FBgn0065848.html gene l(2)SH2 0310 16-Dec-15 2015_12 "lethal,recessive" FBgn0031979 CCDC53 http://flybase.net/reports/FBgn0031979.html protein_coding_gene 0071203=WASH complex CG7429 "IPR019309=WASH complex, subunit CCDC53" CG7429 16-Dec-15 2015_12 ENSDARG00000045563(ccdc53) WBGene00019125(ddl-1) ENSXETG00000002536(CCDC53) ENSMUSG00000020056(Ccdc53) ENSG00000120860(CCDC53) "female fertile,viable" FBgn0015382 dust double stalk http://flybase.net/reports/FBgn0015382.html gene "0008283=cell proliferation, 0001709=cell fate determination, 0007443=Malpighian tubule morphogenesis" 16-Dec-15 2015_12 FBgn0267109 CR45549 http://flybase.net/reports/FBgn0267109.html non_protein_coding_gene CR45549 16-Dec-15 2015_12 FBgn0266927 CR45378 http://flybase.net/reports/FBgn0266927.html non_protein_coding_gene CR45378 16-Dec-15 2015_12 FBgn0053353 5SrRNA:CR33353 5SrRNA:CR33353 http://flybase.net/reports/FBgn0053353.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33353 CR33353 16-Dec-15 2015_12 FBgn0264886 CR44077 http://flybase.net/reports/FBgn0264886.html non_protein_coding_gene CR44077 16-Dec-15 2015_12 FBgn0260333 GSd423 http://flybase.net/reports/FBgn0260333.html gene 16-Dec-15 2015_12 lethal FBgn0013511 l(1)14Ah lethal (1) 14Ah http://flybase.net/reports/FBgn0013511.html gene "l(1)13Fk, l(1)X, X" 16-Dec-15 2015_12 "lethal,recessive" FBgn0031256 CG4164 http://flybase.net/reports/FBgn0031256.html protein_coding_gene 0051082=unfolded protein binding "0006457=protein folding, 0009408=response to heat" "IPR008971=HSP40/DnaJ peptide-binding, IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site, IPR002939=Chaperone DnaJ, C-terminal" CG4164 16-Dec-15 2015_12 ENSDARG00000015088(dnajb11) WBGene00001038(dnj-20) ENSXETG00000004660(dnajb11) ENSMUSG00000004460(Dnajb11) ENSG00000090520(DNAJB11) "viable,partially lethal - majority die,recessive" FBgn0029800 lin-52 lin-52 http://flybase.net/reports/FBgn0029800.html protein_coding_gene "0007049=cell cycle, 0000122=negative regulation of transcription from RNA polymerase II promoter, 1900118=negative regulation of execution phase of apoptosis, 0048749=compound eye development" "0000791=euchromatin, 0005700=polytene chromosome, 0070176=DRM complex, 0005634=nucleus, 0031523=Myb complex" "dLIN-52, dLin-52, Lin-52, Lin52, dLin52, dlin-52, dlin52, CG15929" IPR018737=Protein LIN52 CG15929 16-Dec-15 2015_12 ENSDARG00000070833(lin52) ENSMUSG00000079991(Gm7020) ENSG00000205659(LIN52) "lethal,visible,somatic clone,germline clone,maternal effect,mitotic cell cycle defective,viable" "eye,somatic clone,rhabdomere | adult stage | somatic clone,ommatidium,embryo,germline clone,maternal effect,mitotic spindle | germline clone | maternal effect,metaphase plate | germline clone | maternal effect" DRSC18106 IE 1.579871404 0.184454313 3.440157772 -0.5260314 -0.496899688 -0.965500096 FBgn0043454 EP639 BEST:SD02913 http://flybase.net/reports/FBgn0043454.html gene "SD02913, BEST:SD02913" 16-Dec-15 2015_12 visible "trichogen cell,ectopic,tormogen cell,macrochaeta,adult thorax,chaeta,wing,germline cell,male,eye,scutellar bristle" FBgn0033297 Mal-A8 Maltase A8 http://flybase.net/reports/FBgn0033297.html protein_coding_gene "0043169=cation binding, 0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process "CT6532, Drome_A8, mal_A8, CG8690" "IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR022567=Glycosyl hydrolase, C-terminal (DUF3459), IPR015902=Glycoside hydrolase, family 13, IPR013781=Glycoside hydrolase, catalytic domain, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily" CG8690 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable FBgn0034476 Toll-7 Toll-7 http://flybase.net/reports/FBgn0034476.html protein_coding_gene "0004888=transmembrane signaling receptor activity, 0046790=virion binding, 0008329=signaling pattern recognition receptor activity, 0005030=neurotrophin receptor activity" "0010508=positive regulation of autophagy, 0007165=signal transduction, 0002752=cell surface pattern recognition receptor signaling pathway, 0006952=defense response, 0050688=regulation of defense response to virus, 0051607=defense response to virus" "0005886=plasma membrane, 0009897=external side of plasma membrane, 0016021=integral component of membrane" "dToll7, TOLL 7, toll, dTLR7, Tl-7, Toll-like, CT24947, toll receptor, CG8595" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR003591=Leucine-rich repeat, typical subtype, IPR000372=Leucine-rich repeat N-terminal domain, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR001611=Leucine-rich repeat" CG8595 16-Dec-15 2015_12 WBGene00006593(tol-1) "ENSXETG00000004577(),ENSXETG00000018306()" ENSMUSG00000033777(Tlr13) "ENSG00000165300(SLITRK5),ENSG00000185985(SLITRK2),ENSG00000121871(SLITRK3),ENSG00000179542(SLITRK4),ENSG00000184564(SLITRK6),ENSG00000178235(SLITRK1)" " embryonic stage -- adult stage , adult stage | male " "immune response defective,lethal,partially lethal - majority die,viable,neuroanatomy defective,decreased cell death" "adult abdomen,macrochaeta,ectopic,eye,wing vein,wing,leg,ventral thoracic disc,wing disc,embryonic/larval central nervous system" FBgn0021804 l(2)k16805 lethal (2) k16805 http://flybase.net/reports/FBgn0021804.html gene l(2)k16805 16-Dec-15 2015_12 "lethal,recessive" FBgn0030676 CG12379 http://flybase.net/reports/FBgn0030676.html protein_coding_gene 0008270=zinc ion binding "IPR007853=Zinc finger, DNL-type, IPR024158=Mitochondrial import protein TIM15" CG12379 16-Dec-15 2015_12 FBgn0026169 snoRNA:ë¬18S-1820 http://flybase.net/reports/FBgn0026169.html snoRNA_gene 0005730=nucleolus "snoR639, snoH1, H1, Sno H1, chr2R:19683803..19683909, snoRNA:H1, snoRNA H1, CR32884, psi18s-1820 snoRNA, Psi 18S-1820(SnoR639), unnamed, Dm-639" CR32884 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0000854 fs(1)M46 female sterile (1) M46 http://flybase.net/reports/FBgn0000854.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0259991 CG42488 http://flybase.net/reports/FBgn0259991.html protein_coding_gene Dromel_CG5116_FBtr0084877_uORF CG42488 16-Dec-15 2015_12 ENSDARG00000067681(zgc:153677) ENSXETG00000003949(TMEM141) ENSMUSG00000026939(Tmem141) FBgn0052379 CG32379 http://flybase.net/reports/FBgn0052379.html FBgn0035778 protein_coding_gene "0004180=carboxypeptidase activity, 0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis CG18415 "IPR000834=Peptidase M14, carboxypeptidase A" CG32379 16-Dec-15 2015_12 FBgn0016939 smiUNK smell impaired unknown http://flybase.net/reports/FBgn0016939.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0002871 mu1 mutator 1 http://flybase.net/reports/FBgn0002871.html gene "mt, mu, mutator" 16-Dec-15 2015_12 FBgn0031981 CG7466 http://flybase.net/reports/FBgn0031981.html protein_coding_gene 0005509=calcium ion binding 0016020=membrane "IPR002165=Plexin repeat, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site, IPR016201=Plexin-like fold, IPR015915=Kelch-type beta propeller, IPR002049=Laminin EGF domain, IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR001881=EGF-like calcium-binding domain, IPR000859=CUB domain" CG7466 16-Dec-15 2015_12 ENSMUSG00000045039(Megf8) ENSG00000105429(MEGF8) viable FBgn0043551 Tsp40A Tetraspanin 40A http://flybase.net/reports/FBgn0043551.html gene 0016021=integral component of membrane "Dm.Tsp40A, unnamed" 16-Dec-15 2015_12 FBgn0034689 CG2921 http://flybase.net/reports/FBgn0034689.html protein_coding_gene IPR002791=Domain of unknown function DUF89 CG2921 16-Dec-15 2015_12 ENSDARG00000055676(zgc:110816) YMR027W() WBGene00009290(F31D4.2) ENSXETG00000008483(BC075279.1) ENSMUSG00000061759(1700052N19Rik) ENSG00000146476(C6orf211) "viable,fertile" FBgn0263853 GS9605 http://flybase.net/reports/FBgn0263853.html gene 16-Dec-15 2015_12 FBgn0060475 l(3)S111703 lethal (3) S111703 http://flybase.net/reports/FBgn0060475.html gene 1117/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052060 CG32060 http://flybase.net/reports/FBgn0052060.html protein_coding_gene 0046331=lateral inhibition 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0000851 fs(1)M40 female sterile (1) M40 http://flybase.net/reports/FBgn0000851.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0259756 ms(2)Fra-1 http://flybase.net/reports/FBgn0259756.html gene "0051276=chromosome organization, 0007283=spermatogenesis" 16-Dec-15 2015_12 male sterile "Y chromosome loop,spermatozoon" FBgn0027094 Aats-ala Alanyl-tRNA synthetase http://flybase.net/reports/FBgn0027094.html protein_coding_gene "0003676=nucleic acid binding, 0004813=alanine-tRNA ligase activity, 0005524=ATP binding" 0006419=alanyl-tRNA aminoacylation 0005737=cytoplasm "AlaRS, CG13391, alaS, ARS" "IPR018162=Alanine-tRNA ligase, class IIc, anti-codon-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR002318=Alanine-tRNA ligase, class IIc, IPR018163=Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR003156=DHHA1 domain, IPR012947=Threonyl/alanyl tRNA synthetase, SAD, IPR018164=Alanyl-tRNA synthetase, class IIc, N-terminal, IPR018165=Alanyl-tRNA synthetase, class IIc, core domain, IPR023033=Alanine-tRNA ligase, eukaryota/bacteria" CG13391 16-Dec-15 2015_12 ENSDARG00000069142(zgc:113920) YOR335C(ALA1) WBGene00000197(aars-2) ENSXETG00000000001(AARS2) ENSMUSG00000031960(Aars) ENSG00000090861(AARS) embryonic stage embryonic/larval salivary gland

lethal FBgn0002467 l(3)SG22 lethal (3) SG22 http://flybase.net/reports/FBgn0002467.html gene l(3)15m-15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0035328 yellow-g2 yellow-g2 http://flybase.net/reports/FBgn0035328.html protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "CG13804, yg2, yel-g2, g2" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG13804 16-Dec-15 2015_12 viable FBgn0032029 CG17292 http://flybase.net/reports/FBgn0032029.html protein_coding_gene 0004806=triglyceride lipase activity 0005829=cytosol "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG17292 16-Dec-15 2015_12 viable FBgn0033756 CG17760 http://flybase.net/reports/FBgn0033756.html FBgn0062862 protein_coding_gene "0001664=G-protein coupled receptor binding, 0031683=G-protein beta/gamma-subunit complex binding, 0003924=GTPase activity, 0005525=GTP binding, 0004871=signal transducer activity" "0060158=phospholipase C-activating dopamine receptor signaling pathway, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway" "0005834=heterotrimeric G-protein complex, 0031234=extrinsic component of cytoplasmic side of plasma membrane" BcDNA:SD21019 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR000654=G-protein alpha subunit, group Q, IPR011025=G protein alpha subunit, helical insertion" CG17760 16-Dec-15 2015_12 viable DRSC06694 E -0.065895759 0.423783124 1.563835556 0.936346256 -0.037558357 0.284170681 FBgn0266470 pinenut http://flybase.net/reports/FBgn0266470.html gene pine nut 16-Dec-15 2015_12 lethal "egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell" FBgn0000146 aub aubergine http://flybase.net/reports/FBgn0000146.html "FBgn0010310, FBgn0024835" protein_coding_gene "0034584=piRNA binding, 0003723=RNA binding" "0046011=regulation of oskar mRNA translation, 0007076=mitotic chromosome condensation, 0006446=regulation of translational initiation, 0046012=positive regulation of oskar mRNA translation, 0007317=regulation of pole plasm oskar mRNA localization, 0046594=maintenance of pole plasm mRNA location, 0046843=dorsal appendage formation, 0017145=stem cell division, 0016246=RNA interference, 0007318=pole plasm protein localization, 0048477=oogenesis, 0035282=segmentation, 0030717=karyosome formation, 0045089=positive regulation of innate immune response, 0010529=negative regulation of transposition, 0000398=mRNA splicing, via spliceosome, 0006342=chromatin silencing, 0050829=defense response to Gram-negative bacterium, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0007282=cystoblast division, 0001556=oocyte maturation, 0007279=pole cell formation, 0030423=targeting of mRNA for destruction involved in RNA interference" "0071011=precatalytic spliceosome, 0005737=cytoplasm, 0005875=microtubule associated complex, 0071013=catalytic step 2 spliceosome, 0043186=P granule" "ms(2)32D, AUBERGINE, sti, sting, Aub, CG6137, Aubergine, AUB, stellate-interacting gene" "IPR012337=Ribonuclease H-like domain, IPR003100=PAZ domain, IPR003165=Piwi domain" CG6137 16-Dec-15 2015_12 "WBGene00004178(prg-1),WBGene00004179(prg-2)" " adult stage | female , adult stage | male " " ovary

, testis

" "lethal,maternal effect,recessive,female sterile,mitotic cell cycle defective,female,lethal - all die before end of embryonic stage,male sterile,wild-type,non-rescuable maternal effect,some die during embryonic stage,suppressor of variegation,non-suppressor of variegation,dominant,viable" "embryo,maternal effect,posterior,dorsal appendage,chorion,female germline stem cell,cystoblast,embryonic/larval cuticle,spermatocyte,spermatid,karyosome" FBgn0262213 mir-2495 mir-2495 stem loop http://flybase.net/reports/FBgn0262213.html miRNA_gene "dme-mir-2495, CR42920" CR42920 16-Dec-15 2015_12 viable FBgn0032597 CG17904 http://flybase.net/reports/FBgn0032597.html protein_coding_gene "0051539=4 iron, 4 sulfur cluster binding, 0051536=iron-sulfur cluster binding" 0016226=iron-sulfur cluster assembly 0005829=cytosol Nubp1 "IPR019591=Mrp/NBP35 ATP-binding protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR028601=Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35" CG17904 16-Dec-15 2015_12 ENSDARG00000055472(nubp1) YGL091C(NBP35) WBGene00008664(F10G8.6) ENSXETG00000007991(NUBP1) ENSMUSG00000022503(Nubp1) ENSG00000103274(NUBP1) viable FBgn0044824 R1A1-element\ORF2 ORF2 http://flybase.net/reports/FBgn0044824.html FBgn0044022 transposable_element_gene "R1-element\ORF2, R1" "IPR005135=Endonuclease/exonuclease/phosphatase, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0012038 Antp::Scr Antp::Scr http://flybase.net/reports/FBgn0012038.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 "lethal,heat sensitive" "head,T1 beard,ectopic,mesothoracic segment,metathoracic segment,arista,tarsal segment,eye,occiput,prothoracic segment,metatarsus,third segment of antenna,heat sensitive,femur,embryonic head,adult head,antenna,embryonic/larval salivary gland,thoracic segment,denticle,mesothoracic leg" FBgn0031972 Wwox WW domain containing oxidoreductase http://flybase.net/reports/FBgn0031972.html FBgn0025543 protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" "0050829=defense response to Gram-negative bacterium, 2000377=regulation of reactive oxygen species metabolic process, 0010165=response to X-ray" 0005737=cytoplasm "DmWWOX, Wwox, anon-EST:Posey177, CG7221" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase, IPR001202=WW domain" CG7221 16-Dec-15 2015_12 ENSDARG00000007614 YOR246C() "WBGene00017082(DC2.5),WBGene00017131(E04F6.15),WBGene00000971(dhs-7),WBGene00000972(dhs-8),WBGene00010762(K10H10.6),WBGene00017971(F32A5.8)" ENSMUSG00000004637(Wwox) ENSG00000186153(WWOX) "viable,fertile" DRSC22872 K 0.442505481 1.199127844 -0.486242807 1.059459968 -0.380161871 -1.583997227 FBgn0037668 CG16736 http://flybase.net/reports/FBgn0037668.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG16736 16-Dec-15 2015_12 FBgn0031792 CG13983 http://flybase.net/reports/FBgn0031792.html protein_coding_gene 0046331=lateral inhibition CG13983 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary,trichogen cell" DRSC02315 K 0.003721968 -0.20044766 0.287670762 0.489890641 1.53554137 0.335697266 FBgn0084286 Rst(1b)Cyr Resistance 1b Cyromazine http://flybase.net/reports/FBgn0084286.html gene 16-Dec-15 2015_12 "chemical resistant,dominant,partially" FBgn0060670 l(3)S079101 lethal (3) S079101 http://flybase.net/reports/FBgn0060670.html gene 0791/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262401 mir-285 mir-285 stem loop http://flybase.net/reports/FBgn0262401.html "FBgn0082174, FBgn0262234" miRNA_gene "dme-mir-285, CR42941, mir-285, miR-285, CR33601" CR42941 16-Dec-15 2015_12 "viable,visible,lethal" wing FBgn0266694 CR45184 http://flybase.net/reports/FBgn0266694.html non_protein_coding_gene CR45184 16-Dec-15 2015_12 FBgn0034898 CG18128 http://flybase.net/reports/FBgn0034898.html protein_coding_gene 0004731=purine-nucleoside phosphorylase activity 0009116=nucleoside metabolic process "IPR000845=Nucleoside phosphorylase domain, IPR001369=PNP/MTAP phosphorylase, IPR011268=Purine nucleoside phosphorylase" CG18128 16-Dec-15 2015_12 YLR209C(PNP1) "partially lethal - majority die,visible" mesothoracic tergum FBgn0085564 CG41234 http://flybase.net/reports/FBgn0085564.html FBan0041234 protein_coding_gene 16-Dec-15 2015_12 FBgn0039677 ppk30 pickpocket 30 http://flybase.net/reports/FBgn0039677.html protein_coding_gene 0005272=sodium channel activity "0006814=sodium ion transport, 2000331=regulation of terminal button organization" 0016021=integral component of membrane "pickpocket 30, ppk30, CG18110" "IPR001873=Na+ channel, amiloride-sensitive" CG18110 16-Dec-15 2015_12 "viable,lethal" FBgn0003547 su(Bar) suppressor of Bar http://flybase.net/reports/FBgn0003547.html gene "M(B), m(B), Modifier-of-Bar, modifier of Bar, su(B)" 16-Dec-15 2015_12 ommatidium FBgn0058307 CG40307 http://flybase.net/reports/FBgn0058307.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028199 l(3)S020114 lethal (3) S020114 http://flybase.net/reports/FBgn0028199.html gene 0201/14 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0034918 Pym Partner of Y14 and Mago http://flybase.net/reports/FBgn0034918.html "FBgn0027071, FBgn0050176" protein_coding_gene "0003723=RNA binding, 1990448=exon-exon junction complex binding, 0043024=ribosomal small subunit binding, 0008190=eukaryotic initiation factor 4E binding, 0031370=eukaryotic initiation factor 4G binding, 0005515=protein binding" "1903259=exon-exon junction complex disassembly, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0002191=cap-dependent translational initiation" 0005737=cytoplasm "pym, Pym, CG30176, Wibg, undefined 3, within bgcn, BEST:HL05757, UD3, PYM, CG10330, wibg" IPR015362=WIBG family CG30176 16-Dec-15 2015_12 ENSDARG00000046024(zgc:65891) WBGene00011871(T20G5.9) ENSXETG00000021850(WIBG) ENSMUSG00000064030 ENSG00000170473(WIBG) "female fertile,female semi-sterile,grandchildless,viable,lethal,recessive" ovary FBgn0000409 Cyt-c-p Cytochrome c proximal http://flybase.net/reports/FBgn0000409.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0045155=electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity" 0006119=oxidative phosphorylation "0005759=mitochondrial matrix, 0005739=mitochondrion, 0005743=mitochondrial inner membrane, 0005829=cytosol" "cytochrome c DC4, Cytc, pDMc01, dc4, CG17903, Cytochrome-c-proximal, DMc01, cyt-c-p, cytochrome-c-p, cyt c-p, Cyct-c-p, CytC, Cytochrome c, Cyt-c2, CYC, cytochrome c, DC4, Cytc-p, dCyt.C-p, cyt.c, Cyt c, CytC-2, cyt c, cyt-c2, Cyt C, Cytochrome C, cytochrome C" "IPR002327=Cytochrome c, class IA/ IB, IPR009056=Cytochrome c-like domain" CG17903 16-Dec-15 2015_12 ENSDARG00000044562(zgc:86706) "YJR048W(CYC1),YEL039C(CYC7)" "WBGene00017121(cyc-2.1),WBGene00013854(cyc-2.2)" "ENSXETG00000008472(cycs),ENSXETG00000027531(BC059740.1)" "ENSMUSG00000058927(Gm10053),ENSMUSG00000063694(Cycs),ENSMUSG00000062813(Gm10121),ENSMUSG00000056436(Cyct)" "ENSG00000172115(CYCS),ENSG00000184844" " adult stage , larval stage--adult stage " " adult thorax

, adult head

, adult abdomen

" "lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible" "trichogen cell,mesothoracic tergum" FBgn0086662 snoRNA:ë¬28S-3186 snoRNA:ë¬28S-3186 http://flybase.net/reports/FBgn0086662.html "FBgn0065077, FBgn0082977, FBgn0053709" snoRNA_gene 0005730=nucleolus "snoR165, CR33709, pug28S-3186, psi-28S-3168, Dm-165, snoRNA:165, Psi 28S-3186(SnoR165), psi28s-3186" CR33709 16-Dec-15 2015_12 FBgn0087012 5-HT2A 5-hydroxytryptamine (serotonin) receptor 2A http://flybase.net/reports/FBgn0087012.html "FBgn0013743, FBgn0025495" protein_coding_gene "0001587=Gq/11-coupled serotonin receptor activity, 0008227=G-protein coupled amine receptor activity, 0004993=serotonin receptor activity" "0007377=germ-band extension, 2000253=positive regulation of feeding behavior, 0007210=serotonin receptor signaling pathway" "0016021=integral component of membrane, 0005886=plasma membrane" "l(3)82CDb, 5-HT[[2]]Dro receptor, 5HT-dro[[1]], 5HT-R82A, 5HT2Dro, 5-HT[[2]], lethal (3) 82CDb, 5-HT2, d5-HT2, 5-HT2Dro, 5-HT[[2]]Dro, 5-ht2Dro, 5-HT[[2Dro]], CG1056, 5HT2, 5HT2-Dro, Serotonin receptor 2, Dm5HT2, 5-HT[2]Dro, 5HT[[2Dro]]" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG1056 16-Dec-15 2015_12 "ENSDARG00000058165(LOC559806),ENSDARG00000057029(LOC560808),ENSDARG00000018228(si:dkey-24g18.2),ENSDARG00000013210(LOC798599),ENSDARG00000070940(zgc:194119)" ENSXETG00000009523(HTR2B) "ENSMUSG00000041380(Htr2c),ENSMUSG00000034997(Htr2a),ENSMUSG00000026228(Htr2b)" "ENSG00000147246(HTR2C),ENSG00000102468(HTR2A),ENSG00000135914(HTR2B)" " embryonic stage | stage 5 , embryonic stage | stage >=13 " " organism | even pair rule

, central nervous system | restricted

" FBgn0004903 Rb97D Ribonuclear protein at 97D http://flybase.net/reports/FBgn0004903.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0007283=spermatogenesis, 0007286=spermatid development" "RBP97D, Hrb97D, rb97d, CG6354, ms(3)03445, rbf, R16, Rb97D1" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG6354 16-Dec-15 2015_12 embryonic stage -- adult stage "male sterile,recessive" "nucleus & spermatid,axoneme" FBgn0000148 aw awry http://flybase.net/reports/FBgn0000148.html gene 16-Dec-15 2015_12 "visible,recessive,fertile" wing FBgn0065590 l(2)SH0905 lethal (2) SH0905 http://flybase.net/reports/FBgn0065590.html gene l(2)SH2 0905 16-Dec-15 2015_12 "lethal,recessive" FBgn0005402 l(1)10Bn lethal (1) 10Bn http://flybase.net/reports/FBgn0005402.html gene "l(1)C248, l(1)L19" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0016800 l(1)K1 lethal (1) K1 http://flybase.net/reports/FBgn0016800.html gene K1 16-Dec-15 2015_12 "lethal,recessive" FBgn0262962 CG43273 http://flybase.net/reports/FBgn0262962.html protein_coding_gene CG43273 16-Dec-15 2015_12 FBgn0031255 BBS8 Bardet-Biedl syndrome 8 ortholog (H. sapiens) http://flybase.net/reports/FBgn0031255.html protein_coding_gene "0035058=nonmotile primary cilium assembly, 0042384=cilium assembly" "0005929=cilium, 0034464=BBSome" "BBS8, BBS2, CG13691" "IPR028796=Tetratricopeptide repeat protein 8, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1" CG13691 16-Dec-15 2015_12 WBGene00000244(bbs-8) ENSXETG00000016635(ttc8) ENSMUSG00000021013(Ttc8) ENSG00000165533(TTC8) viable FBgn0020879 anon-43Ba anon-43Ba http://flybase.net/reports/FBgn0020879.html gene tuII 16-Dec-15 2015_12 FBgn0013536 l(2)ry36 lethal (2) ry36 http://flybase.net/reports/FBgn0013536.html gene "l(2)36, unnamed" 16-Dec-15 2015_12 lethal FBgn0283484 CLIP-190::Rnor\Clip1 http://flybase.net/reports/FBgn0283484.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0260340 GSd424 http://flybase.net/reports/FBgn0260340.html gene 16-Dec-15 2015_12 lethal FBgn0046707 GIIIE GIIIE http://flybase.net/reports/FBgn0046707.html gene 0004623=phospholipase A2 activity 0005576=extracellular region dGIIIE 16-Dec-15 2015_12 FBgn0042135 CG18812 http://flybase.net/reports/FBgn0042135.html "FBgn0033217, FBgn0042136" protein_coding_gene "CG18813, CG12040" "IPR002589=Macro domain, IPR001251=CRAL-TRIO lipid binding domain" CG18812 16-Dec-15 2015_12 ENSDARG00000021569(gdap2) ENSXETG00000009921(GDAP2) ENSMUSG00000027865(Gdap2) ENSG00000196505(GDAP2) viable FBgn0038887 CG7907 http://flybase.net/reports/FBgn0038887.html protein_coding_gene 0000339=RNA cap binding "0045292=mRNA cis splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0051028=mRNA transport" "0005845=mRNA cap binding complex, 0005634=nucleus, 0005846=nuclear cap binding complex" "IPR015174=MIF4G-like, type 2, IPR003890=MIF4G-like, type 3, IPR016024=Armadillo-type fold, IPR015172=MIF4G-like, type 1, IPR027159=Nuclear cap-binding protein subunit 1, IPR016021=MIF4G-like domain" CG7907 16-Dec-15 2015_12 YMR125W(STO1) FBgn0032381 Mal-B1 Maltase B1 http://flybase.net/reports/FBgn0032381.html protein_coding_gene "0004558=alpha-1,4-glucosidase activity, 0043169=cation binding" 0005975=carbohydrate metabolic process "mal_B1, Drome_B1, CG14934" "IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR015902=Glycoside hydrolase, family 13, IPR013781=Glycoside hydrolase, catalytic domain, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain" CG14934 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable DRSC02416 EK -0.704395479 0.714998552 3.899972179 0.729753206 -2.763082872 0.436859503 FBgn0003681 ten tenuis chaetae http://flybase.net/reports/FBgn0003681.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile" macrochaeta FBgn0028226 l(3)S005302a lethal (3) S005302a http://flybase.net/reports/FBgn0028226.html gene "0053/02, l(3)S005302" 16-Dec-15 2015_12 "lethal,recessive" FBgn0030385 Ir11a Ionotropic receptor 11a http://flybase.net/reports/FBgn0030385.html protein_coding_gene 0015276=ligand-gated ion channel activity "0050909=sensory perception of taste, 0009593=detection of chemical stimulus" 0016021=integral component of membrane "CG15732, Q9VYN4_DROME, CT35969, IR11a, DmelIR11a, ionotropic receptor 11a" CG15732 16-Dec-15 2015_12 "viable,lethal" FBgn0044000 Su(rst)C40 Su(rst)C40 http://flybase.net/reports/FBgn0044000.html gene 0001745=compound eye morphogenesis C40 16-Dec-15 2015_12 viable FBgn0060658 l(3)S082807 lethal (3) S082807 http://flybase.net/reports/FBgn0060658.html gene 0828/07 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0029036 l(2)N36 lethal (2) N36 http://flybase.net/reports/FBgn0029036.html gene N36 16-Dec-15 2015_12 "lethal,recessive" FBgn0259194 Ir94e Ionotropic receptor 94e http://flybase.net/reports/FBgn0259194.html "FBgn0039076, FBan0017379" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG17379, CG42298, DmelIR94e, ionotropic receptor 94e, IR94e" CG42298 16-Dec-15 2015_12 viable FBgn0000833 fs(1)M15 female sterile (1) M15 http://flybase.net/reports/FBgn0000833.html gene 16-Dec-15 2015_12 "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0015921 cleo cleopatra http://flybase.net/reports/FBgn0015921.html gene 16-Dec-15 2015_12 "viable,female fertile" embryonic/larval brain FBgn0058211 CG40211 http://flybase.net/reports/FBgn0058211.html FBan0040211 protein_coding_gene 16-Dec-15 2015_12 FBgn0014401 tru troupa http://flybase.net/reports/FBgn0014401.html gene 16-Dec-15 2015_12 FBgn0261019 moi modigliani http://flybase.net/reports/FBgn0261019.html "FBgn0026200, FBgn0259681, FBgn0060562" protein_coding_gene "0016233=telomere capping, 0007067=mitotic nuclear division, 0031848=protection from non-homologous end joining at telomere" "0000781=chromosome, telomeric region, 0005705=polytene chromosome interband" "lethal (3) S096713, uORF, upstream ORF of tat-like, tlu, Dtl uORF, 0967/13, DTLu, l(3)S096713, CG42350, Dromel_CG31241_FBtr0083570_dtl_uORF, CG31241, DTL, l(3)CB02140" CG42350 16-Dec-15 2015_12 FBgn0045487 Gr36a Gustatory receptor 36a http://flybase.net/reports/FBgn0045487.html "FBgn0041219, FBgn0051747" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG31747, GR36a, GRLU.1, LU.1, GrLU1, Gustatory receptor LU.1, Gr36B1" IPR013604=7TM chemoreceptor CG31747 16-Dec-15 2015_12 viable FBgn0015369 bushy bushy http://flybase.net/reports/FBgn0015369.html gene bsh 16-Dec-15 2015_12 FBgn0032105 borr borealin-related http://flybase.net/reports/FBgn0032105.html protein_coding_gene "0005515=protein binding, 0003677=DNA binding" "0007052=mitotic spindle organization, 0045448=mitotic cell cycle, embryonic, 0007067=mitotic nuclear division, 0090307=mitotic spindle assembly, 0000281=mitotic cytokinesis, 0016572=histone phosphorylation, 0008104=protein localization" "0032133=chromosome passenger complex, 0000776=kinetochore, 0000785=chromatin, 1990385=meiotic spindle midzone, 0005938=cell cortex, 0051233=spindle midzone" "BORR, Bor, borealin, Borr, CG4454, Borealin-related, Borealin, dBor, borr" IPR018867=Cell division protein borealin CG4454 16-Dec-15 2015_12 "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage,increased cell death,somatic clone,cell size defective,Minute,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "chromatin,trichogen cell,mesothoracic tergum,ventral nerve cord & nucleus,brain & nucleus,nucleus | somatic clone,spindle | somatic clone,leg,somatic clone,eye,wing,wing hair,ectopic,wing margin bristle" FBgn0060671 l(3)S078709 lethal (3) S078709 http://flybase.net/reports/FBgn0060671.html gene 0787/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0265904 CR44693 http://flybase.net/reports/FBgn0265904.html non_protein_coding_gene CR44693 16-Dec-15 2015_12 FBgn0037376 CG2051 http://flybase.net/reports/FBgn0037376.html protein_coding_gene 0004402=histone acetyltransferase activity "0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0016573=histone acetylation, 0006348=chromatin silencing at telomere" 0005634=nucleus dmHAG409 "IPR016181=Acyl-CoA N-acyltransferase, IPR017380=Histone acetyltransferase type B, catalytic subunit, IPR019467=Histone acetyl transferase HAT1 N-terminal" CG2051 16-Dec-15 2015_12 ENSDARG00000034916(hat1) YPL001W(HAT1) WBGene00044069(tag-235) ENSXETG00000007535(HAT1) ENSMUSG00000027018(Hat1) ENSG00000128708(HAT1) viable FBgn0044477 EP1016 EP1016 http://flybase.net/reports/FBgn0044477.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0069917 CG41135 http://flybase.net/reports/FBgn0069917.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031946 CG7164 http://flybase.net/reports/FBgn0031946.html protein_coding_gene CG7164 16-Dec-15 2015_12 FBgn0263131 CG43373 http://flybase.net/reports/FBgn0263131.html "FBgn0036637, FBgn0260387, FBan0032158, FBgn0052158, FBgn0036636" protein_coding_gene 0004016=adenylate cyclase activity "0006171=cAMP biosynthetic process, 0035556=intracellular signal transduction" 0005886=plasma membrane "CG42513, CG32158, AC, Ago2, CG12436" "IPR009398=Adenylate cyclase, conserved domain, IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG43373 16-Dec-15 2015_12 FBgn0036246 CG17154 http://flybase.net/reports/FBgn0036246.html protein_coding_gene CG17154 16-Dec-15 2015_12 viable FBgn0014891 Wedge Wedge http://flybase.net/reports/FBgn0014891.html gene 16-Dec-15 2015_12 "visible,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0029121 Sras severas http://flybase.net/reports/FBgn0029121.html FBgn0035615 protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "0016020=membrane, 0030176=integral component of endoplasmic reticulum membrane" "FAC2_DROME, CG4852, prenyl protease type II" IPR003675=CAAX amino terminal protease CG4852 16-Dec-15 2015_12 YMR274C(RCE1) WBGene00001406(fce-2) ENSXETG00000026642(RCE1) ENSMUSG00000024889(Rce1) ENSG00000173653(RCE1) viable FBgn0028412 Mst33A Mst33A http://flybase.net/reports/FBgn0028412.html protein_coding_gene CG6541 CG6541 16-Dec-15 2015_12 viable FBgn0267985 CR46252 http://flybase.net/reports/FBgn0267985.html non_protein_coding_gene CR46252 16-Dec-15 2015_12 FBgn0017546 Rp34 Ribosomal protein 34 http://flybase.net/reports/FBgn0017546.html gene 0003735=structural constituent of ribosome 0006412=translation 0005840=ribosome rp34 16-Dec-15 2015_12 FBgn0259623 B0531 http://flybase.net/reports/FBgn0259623.html gene 16-Dec-15 2015_12 visible wing FBgn0004826 fs(2)ltoHC44 female sterile (2) ltoHC44 http://flybase.net/reports/FBgn0004826.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0031757 Ucp4C Ucp4C http://flybase.net/reports/FBgn0031757.html "FBgn0063444, FBgn0063445, FBgn0064194, FBgn0064195, FBgn0066863, FBgn0067797, FBgn0067798" protein_coding_gene "0017077=oxidative phosphorylation uncoupler activity, 0022857=transmembrane transporter activity" "0006839=mitochondrial transport, 0055085=transmembrane transport, 0015992=proton transport" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane" "anon-WO03061681.2, dmUCP4c, anon-WO0242455.4, anon-WO03037362.7, Ucp4c, CG9064, UCP4c, anon-WO03061681.1, DmUCP4C, UCP4C, anon-WO02079478.2, anon-WO0242455.3, anon-WO02079478.1" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein" CG9064 16-Dec-15 2015_12 "viable,fertile" FBgn0065922 l(2)SH0153 lethal (2) SH0153 http://flybase.net/reports/FBgn0065922.html gene l(2)SH2 0153 16-Dec-15 2015_12 "lethal,recessive" FBgn0260612 2L2468 http://flybase.net/reports/FBgn0260612.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 viable "dorsal air sac primordium,somatic clone" FBgn0024920 Ts Thymidylate synthase http://flybase.net/reports/FBgn0024920.html protein_coding_gene 0004799=thymidylate synthase activity "0006231=dTMP biosynthetic process, 0022008=neurogenesis, 0009263=deoxyribonucleotide biosynthetic process" "FBgn0024920, TS, c1.5, CG3181, anon-23Ca, thymidilate synthetase, Thymidylate synthase, Ts" "IPR020940=Thymidylate synthase, active site, IPR000398=Thymidylate synthase, IPR023451=Thymidylate synthase/dCMP hydroxymethylase domain" CG3181 16-Dec-15 2015_12 ENSDARG00000042894(tyms) YOR074C(CDC21) WBGene00022455(Y110A7A.4) ENSXETG00000003156(tyms) ENSMUSG00000025747(Tyms) ENSG00000176890(TYMS) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,trichogen cell" FBgn0005153 l(2)G94 lethal (2) G94 http://flybase.net/reports/FBgn0005153.html gene 16-Dec-15 2015_12 lethal FBgn0032208 CG5604 http://flybase.net/reports/FBgn0032208.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0046872=metal ion binding" 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process "0005634=nucleus, 0005737=cytoplasm" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR008979=Galactose-binding domain-like, IPR010606=Mib-herc2, IPR011989=Armadillo-like helical, IPR000569=HECT domain, IPR016024=Armadillo-type fold, IPR012919=SUN domain" CG5604 16-Dec-15 2015_12 ENSDARG00000054213(hectd1) WBGene00016405(hecd-1) ENSXETG00000014149(HECTD1) ENSMUSG00000035247(Hectd1) ENSG00000092148(HECTD1) "viable,visible" mesothoracic tergum FBgn0086690 Plp Pericentrin-like protein http://flybase.net/reports/FBgn0086690.html "FBgn0011807, FBgn0053957, FBgn0036475, FBgn0036473, FBgn0036472" protein_coding_gene "0051297=centrosome organization, 0048598=embryonic morphogenesis, 0007605=sensory perception of sound, 0007020=microtubule nucleation, 0060285=cilium-dependent cell motility" "0005814=centriole, 0005813=centrosome" "pericentrin/AKAP450 centrosomal targeting, d-plp, Cp309, CG33957, CG13459, pPlp, Dplp, DPLP, dplp, Pericentrin, pericentrin-like protein, lethal (3) s2172, Drosophila Pericentrin Like Protein, CP309, pericentrin-like, Plp, D-PLP, pericentrin-like-protein, PLP, l(3)s2172, Pericentrin-like protein, CG6735, AKAP450, plp, CG18648, PACT, cp309, dPLP, pericentrin" IPR019528=Pericentrin/AKAP-450 centrosomal targeting domain CG33957 16-Dec-15 2015_12 ENSDARG00000033012 ENSMUSG00000040407(Akap9) "ENSG00000160299(PCNT),ENSG00000127914(AKAP9)" FBgn0262486 CG43076 http://flybase.net/reports/FBgn0262486.html protein_coding_gene lincRNA.997 CG43076 16-Dec-15 2015_12 FBgn0011129 l(1)Q203 lethal (1) Q203 http://flybase.net/reports/FBgn0011129.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0011954 tRNA:R:19F transfer RNA:arg:19F http://flybase.net/reports/FBgn0011954.html "FBgn0011947, FBgn0052526, FBgn0060078" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033431=CGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002620.trna3-ArgTCG, CR32526, tRNA:R:TCG:AE002620, tRNA:R1, transfer RNA:arg1, tRNA:arg1, tRNA[arg], tRNA-Arg, chrX.trna16-ArgTCG, tRNA:arg19F" CR32526 16-Dec-15 2015_12 FBgn0052282 Drsl4 Drosomycin-like 4 http://flybase.net/reports/FBgn0052282.html protein_coding_gene "0006952=defense response, 0050832=defense response to fungus" 0005576=extracellular region "Dro4, Drs-lF, dros4, CG32282, dro-4, Dro-4, Drosomycin 4, Drosomycin-like F, drosmycin-4, drosomycin-4, Drosomycin-4, dro4, drosomycin, drosomycin-F" "IPR003614=Knottin, scorpion toxin-like" CG32282 16-Dec-15 2015_12 viable FBgn0026573 ADD1 ADD domain-containing protein 1 http://flybase.net/reports/FBgn0026573.html FBgn0033670 protein_coding_gene "0031490=chromatin DNA binding, 0035064=methylated histone binding, 0005515=protein binding" 0070868=heterochromatin organization involved in chromatin silencing "0005634=nucleus, 0005700=polytene chromosome, 0005721=pericentric heterochromatin" "BEST:LD29214, CG8290, dADD1, LD29214" "IPR025766=ADD domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR006578=MADF domain, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG8290 16-Dec-15 2015_12 "ENSDARG00000042236,ENSDARG00000057892" "viable,suppressor of variegation,dominant,lethal" FBgn0065732 l(2)SH0551 lethal (2) SH0551 http://flybase.net/reports/FBgn0065732.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0063648 CE2-1 "Calcineurin enhancer, chromosome 2, group 1" http://flybase.net/reports/FBgn0063648.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001538 l(1)14Cb lethal (1) 14Cb http://flybase.net/reports/FBgn0001538.html gene "l(1)k17a, k17a" 16-Dec-15 2015_12 lethal FBgn0016945 tilA touch insensitive larva A http://flybase.net/reports/FBgn0016945.html gene 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0060561 l(3)S096805a lethal (3) S096805a http://flybase.net/reports/FBgn0060561.html gene 0968/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0019763 l(1)6c-21 lethal (1) 6c-21 http://flybase.net/reports/FBgn0019763.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067622 LSm-4 Like Sm protein 4 http://flybase.net/reports/FBgn0067622.html "FBgn0051990, FBgn0053677, FBgn0062864, FBtr0080048, FBpp0079638, FBtr0080049, FBpp0079639" protein_coding_gene "0000381=regulation of alternative mRNA splicing, via spliceosome" "CG31990, CG33677, LSM4, BcDNA:SD20015, CG31990-ORFA, LSm4" "IPR017920=COMM domain, IPR009886=HCaRG" CG33677 16-Dec-15 2015_12 ENSDARG00000029660(zgc:101132) ENSXETG00000004328(COMMD5) ENSMUSG00000055041(Commd5) "ENSG00000170619(COMMD5),ENSG00000173966" FBgn0030098 CG12057 http://flybase.net/reports/FBgn0030098.html FBgn0063115 protein_coding_gene BcDNA:LP05863 IPR007931=Protein of unknown function DUF725 CG12057 16-Dec-15 2015_12 viable FBgn0033229 CG12822 http://flybase.net/reports/FBgn0033229.html protein_coding_gene CG12822-PA "IPR023370=TsaA-like domain, IPR001378=Uncharacterised domain UPF0066" CG12822 16-Dec-15 2015_12 ENSDARG00000037245(zgc:123172) ENSXETG00000010182(C9orf156) ENSMUSG00000028331(5830415F09Rik) ENSG00000136932(C9orf156) viable FBgn0084555 bda belinda http://flybase.net/reports/FBgn0084555.html gene 16-Dec-15 2015_12 FBgn0261822 Bsg Basigin http://flybase.net/reports/FBgn0261822.html "FBgn0011219, FBgn0010613, FBgn0021878, FBgn0022015, FBgn0022136, FBgn0046227, FBgn0051605, FBgn0065497" protein_coding_gene "0051646=mitochondrion localization, 0002121=inter-male aggressive behavior, 0007286=spermatid development, 0008594=photoreceptor cell morphogenesis, 0016337=single organismal cell-cell adhesion, 0051647=nucleus localization, 0051643=endoplasmic reticulum localization, 0045214=sarcomere organization" "0048786=presynaptic active zone, 0048788=presynaptic cytoskeletal matrix assembled at active zones, 0005886=plasma membrane" "l(2)k06338, gelded, l(2)SH2 1217, gel, l(2)k09030, NP6293, bsg, l(2)k14308, D-basigin, l(2)k13638, lethal (2) SH1217, CG31605, basigin, 135/10, l(2)SH1217, l(2)06243, BcDNA:GH21853, ms(2)08318" "IPR013783=Immunoglobulin-like fold, IPR013151=Immunoglobulin, IPR007110=Immunoglobulin-like domain, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG31605 16-Dec-15 2015_12 FBgn0266306 CR44971 http://flybase.net/reports/FBgn0266306.html non_protein_coding_gene CR44971 16-Dec-15 2015_12 FBgn0263762 CG43679 http://flybase.net/reports/FBgn0263762.html protein_coding_gene CG43679 16-Dec-15 2015_12 FBgn0029504 CHES-1-like Checkpoint suppressor homologue http://flybase.net/reports/FBgn0029504.html "FBgn0027673, FBgn0029954" protein_coding_gene "0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000976=transcription regulatory region sequence-specific DNA binding, 0008301=DNA binding, bending" "0051090=regulation of sequence-specific DNA binding transcription factor activity, 0006355=regulation of transcription, DNA-templated, 0009888=tissue development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0031571=mitotic G1 DNA damage checkpoint, 0007389=pattern specification process, 0035050=embryonic heart tube development, 0051302=regulation of cell division, 0006909=phagocytosis, 0071456=cellular response to hypoxia" "0005634=nucleus, 0005667=transcription factor complex" "Ches-1-like, anon-EST:Posey7, Ches1, Dmches-1, FoxN, ches1, CG12690, ches-1-like" "IPR001766=Fork head domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR018122=Fork head domain conserved site1" CG12690 16-Dec-15 2015_12 WBGene00001439(fkh-7) "ENSXETG00000011856(foxp4),ENSXETG00000008510(FOXP1)" "ENSMUSG00000023991(Foxp4),ENSMUSG00000029563(Foxp2),ENSMUSG00000030067(Foxp1)" "ENSG00000137166(FOXP4),ENSG00000128573(FOXP2),ENSG00000114861(FOXP1)" "increased cell death,visible,lethal - all die before end of pupal stage,some die during pupal stage" "heart primordium,eye,embryonic/larval cardial cell,embryonic/larval pericardial cell" DRSC18447 E -0.214597937 -0.6701924 -0.225185765 1.860905836 -0.53349305 -0.051556223 FBgn0052504 CG32504 http://flybase.net/reports/FBgn0052504.html protein_coding_gene 16-Dec-15 2015_12 DRSC22745 K 0.438939617 0.400901782 0.122521301 0.110423734 -1.225817522 -1.712639293 FBgn0060436 l(3)S125012b lethal (3) S125012b http://flybase.net/reports/FBgn0060436.html gene 1250/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0005267 l(3)SG87 lethal (3) SG87 http://flybase.net/reports/FBgn0005267.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026263 bip1 bip1 http://flybase.net/reports/FBgn0026263.html FBgn0062148 protein_coding_gene "0003676=nucleic acid binding, 0031208=POZ domain binding" 0035167=larval lymph gland hemopoiesis "bip-I, Bip1, CG7574, Bab Interating Protein 1, anon-WO0118547.246" "IPR006612=Zinc finger, C2CH-type" CG7574 16-Dec-15 2015_12 "viable,female fertile" FBgn0085356 CG34327 http://flybase.net/reports/FBgn0085356.html protein_coding_gene CG34327 16-Dec-15 2015_12 FBgn0266040 CR44805 http://flybase.net/reports/FBgn0266040.html non_protein_coding_gene lincRNA.S3687 CR44805 16-Dec-15 2015_12 FBgn0001970 Pgant35A Polypeptide N-acetylgalactosaminyltransferase 35A http://flybase.net/reports/FBgn0001970.html "FBgn0027860, FBgn0032545" protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity "0007424=open tracheal system development, 0009312=oligosaccharide biosynthetic process" 0005795=Golgi stack "l35Aa, br12, A3, l(2)br12, pgant35A, CG7480, lethal group A3, dGalNAc-T1, pgant35, GalNAc-T, l(2)35Aa, BG:DS01068.8, lethal 12 in the black-reduced region" "IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain, IPR029044=Nucleotide-diphospho-sugar transferases" CG7480 16-Dec-15 2015_12 ENSDARG00000063636(galnt11) ENSMUSG00000038072(Galnt11) ENSG00000178234(GALNT11) " oogenesis stage , adult stage | female , embryonic stage | early , embryonic stage -- adult stage , embryonic stage&&larval stage&&adult stage , adult stage | male " " follicle cell

, ovary

, testis

, germline cell

" "lethal,partially lethal - majority die,wild-type,recessive,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "embryonic/larval dorsal trunk,embryonic/larval tracheal system" DRSC03557 K 1.199900284 0.133253465 0.213235553 0.229465897 1.648178344 0.595455836 FBgn0001700 l(1)ESHS21 lethal (1) ESHS21 http://flybase.net/reports/FBgn0001700.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262777 Su(E1)-K http://flybase.net/reports/FBgn0262777.html gene 16-Dec-15 2015_12 FBgn0085609 CG41314 http://flybase.net/reports/FBgn0085609.html FBan0041314 protein_coding_gene 16-Dec-15 2015_12 FBgn0038569 CG7218 http://flybase.net/reports/FBgn0038569.html protein_coding_gene "IPR008010=Membrane protein,Tapt1/CMV receptor" CG7218 16-Dec-15 2015_12 ENSDARG00000061143(tapt1) YER140W() WBGene00009172(F26F2.7) ENSXETG00000020338(TAPT1) ENSMUSG00000046985(Tapt1) ENSG00000169762(TAPT1) viable FBgn0034007 ND-51L2 NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 2 http://flybase.net/reports/FBgn0034007.html protein_coding_gene "0003954=NADH dehydrogenase activity, 0051539=4 iron, 4 sulfur cluster binding, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone, 0032504=multicellular organism reproduction" "0005747=mitochondrial respiratory chain complex I, 0005615=extracellular space" "NADH:ubiquinone oxidoreductase 51 kDa subunit, CG8102, NADH-UBIQUINONE OXIDOREDUCTASE 51 KDA SUBUNIT, NUBM" "IPR011538=NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019575=NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain, IPR019554=Soluble ligand binding domain" CG8102 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0037081 barc barricade http://flybase.net/reports/FBgn0037081.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0030182=neuron differentiation, 0022008=neurogenesis" 0005634=nucleus "cg6049, Tat-SF1, CG6049, cus2" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG6049 16-Dec-15 2015_12 ENSDARG00000056649(htatsf1) WBGene00022025(Y65B4A.1) ENSXETG00000019749(htatsf1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0022177 l(2)k05404 lethal (2) k05404 http://flybase.net/reports/FBgn0022177.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004910 Eip63F-1 Ecdysone-induced protein 63F 1 http://flybase.net/reports/FBgn0004910.html FBgn0035474 protein_coding_gene 0005509=calcium ion binding "0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death" "0005886=plasma membrane, 0005737=cytoplasm, 0005634=nucleus" "Eip63Fa, E63F, E63-1, eip63F-1, Eip63-1, Eip63F1, Ca[2+] binding protein, 63F-1, CG15855" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG15855 16-Dec-15 2015_12 " larval stage , pupal stage | 0-8hr , pupal stage | 32-96hr , larval stage | late , embryonic stage && larval stage , embryonic stage | late " " embryonic/larval salivary gland

, embryonic/larval fat body

, ventral nerve cord

, epidermis

, embryonic/larval midgut

, larval brain

, imaginal disc

" "oxidative stress response defective,viable,fertile" FBgn0015233 Gpdh-ë¬ Glycerol 3 phosphate dehydrogenase pseudogene http://flybase.net/reports/FBgn0015233.html pseudogene_attribute "unnamed, 3' gene" 16-Dec-15 2015_12 FBgn0022379 Pt-11 Larval protein-11 http://flybase.net/reports/FBgn0022379.html gene 16-Dec-15 2015_12 FBgn0266846 CR45308 http://flybase.net/reports/FBgn0266846.html non_protein_coding_gene CR45308 16-Dec-15 2015_12 FBgn0266758 Esyt2 Extended synaptotagmin-like protein 2 ortholog (H. sapiens) http://flybase.net/reports/FBgn0266758.html "FBgn0039208, FBgn0044808" protein_coding_gene 0005544=calcium-dependent phospholipid binding "0046907=intracellular transport, 0016079=synaptic vesicle exocytosis" "0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0008021=synaptic vesicle" "CG6643, Tricalbin" IPR000008=C2 domain CG6643 16-Dec-15 2015_12 "ENSDARG00000014239(esyt1b),ENSDARG00000034714(esyt1a)" "YNL087W(TCB2),YOR086C(TCB1),YML072C(TCB3)" WBGene00020443(esyt-2) "ENSXETG00000007167(ESYT2),ENSXETG00000009481(ESYT1)" "ENSMUSG00000021171(Esyt2),ENSMUSG00000037681(Esyt3),ENSMUSG00000025366(Esyt1)" "ENSG00000117868(ESYT2),ENSG00000139641(ESYT1),ENSG00000158220(ESYT3)" FBgn0030344 CG2025 http://flybase.net/reports/FBgn0030344.html protein_coding_gene "0004222=metalloendopeptidase activity, 0046872=metal ion binding" 0006508=proteolysis "IPR011765=Peptidase M16, N-terminal, IPR011237=Peptidase M16 domain, IPR007863=Peptidase M16, C-terminal, IPR001431=Peptidase M16, zinc-binding site, IPR011249=Metalloenzyme, LuxS/M16 peptidase-like" CG2025 16-Dec-15 2015_12 "ENSDARG00000019596(wu:fk24c07),ENSDARG00000062372(nrd1)" ENSXETG00000008054(NRD1) ENSMUSG00000053510(Nrd1) ENSG00000078618(NRD1) "lethal,recessive,viable" FBgn0261502 CG42650 http://flybase.net/reports/FBgn0261502.html protein_coding_gene DMG4-MB6.chr3R.6.014 CG42650 16-Dec-15 2015_12 FBgn0051527 CG31527 http://flybase.net/reports/FBgn0051527.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001852 l(1)tsUC13 lethal (1) tsUC13 http://flybase.net/reports/FBgn0001852.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0031361 CG17652 http://flybase.net/reports/FBgn0031361.html protein_coding_gene 0006909=phagocytosis 0032040=small-subunit processome "IPR029060=PIN domain-like, IPR006984=rRNA-processing protein Fcf1/Utp23" CG17652 16-Dec-15 2015_12 ENSDARG00000028249(zgc:110214) YOR004W(UTP23) WBGene00016411(C34E10.10) ENSXETG00000020781(TEgg016n21.1) ENSMUSG00000022313(Utp23) ENSG00000147679(UTP23) FBgn0011044 l(1)Stark-c lethal (1) of Stark c http://flybase.net/reports/FBgn0011044.html FBgn0010212 gene "lethal (1) Sc, l(1)Sc" 16-Dec-15 2015_12 lethal FBgn0029661 CG16781 http://flybase.net/reports/FBgn0029661.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0000209=protein polyubiquitination "0005789=endoplasmic reticulum membrane, 0005741=mitochondrial outer membrane" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011016=Zinc finger, RING-CH-type" CG16781 16-Dec-15 2015_12 viable FBgn0039992 CG12416 http://flybase.net/reports/FBgn0039992.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004932 a(1)HM27 abnormal abdomen HM27 http://flybase.net/reports/FBgn0004932.html gene l(1)HM27 16-Dec-15 2015_12 "visible,recessive,cold sensitive" "tergite,sternite" FBgn0010615 l(2)06253 lethal (2) 06253 http://flybase.net/reports/FBgn0010615.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0037003 CG18281 http://flybase.net/reports/FBgn0037003.html protein_coding_gene 0005215=transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR001958=Tetracycline resistance protein, TetA/multidrug resistance protein MdtG, IPR020846=Major facilitator superfamily domain" CG18281 16-Dec-15 2015_12 FBgn0050202 tRNA:CR30202 transfer RNA:CR30202 http://flybase.net/reports/FBgn0050202.html FBgn0060053 tRNA_gene 0033407=UCA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA[[Ser]], chr2R.trna48-SerTGA, tRNA:S:TGA:AE002575-a, CR30202, AE002575.trna4-SerTGA" CR30202 16-Dec-15 2015_12 FBgn0041842 E(Sev-CycE)E19 E(Sev-CycE)E19 http://flybase.net/reports/FBgn0041842.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266501 s-251 http://flybase.net/reports/FBgn0266501.html gene 16-Dec-15 2015_12 FBgn0063916 McClintock\gag gag http://flybase.net/reports/FBgn0063916.html transposable_element_gene 16-Dec-15 2015_12 FBgn0058043 CG40043 http://flybase.net/reports/FBgn0058043.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039145 CG6000 http://flybase.net/reports/FBgn0039145.html FBgn0047123 protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding BcDNA:RE30346 IPR001763=Rhodanese-like domain CG6000 16-Dec-15 2015_12 ENSDARG00000071567(LOC563265) "YOR286W(RDL2),YOR285W(RDL1)" ENSMUSG00000028251(2610029I01Rik) ENSG00000215845(TSTD1) viable FBgn0062593 Mod(var)1551 Mod(var)1551 http://flybase.net/reports/FBgn0062593.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1551 16-Dec-15 2015_12 "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,lethal" FBgn0001192 hi high http://flybase.net/reports/FBgn0001192.html gene 16-Dec-15 2015_12 FBgn0001643 l(1)dn23 lethal (1) discs normal 23 http://flybase.net/reports/FBgn0001643.html gene l(1)d.norm.-23 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267102 CR45542 http://flybase.net/reports/FBgn0267102.html non_protein_coding_gene CR45542 16-Dec-15 2015_12 FBgn0263035 CG43330 http://flybase.net/reports/FBgn0263035.html "FBgn0037168, FBan0012377" protein_coding_gene CG12377 CG43330 16-Dec-15 2015_12 FBgn0002369 l(3)91Fa lethal (3) 91Fa http://flybase.net/reports/FBgn0002369.html FBgn0002375 gene "l(3)BE41, l(3)BE44, C2, l(3)BE40, l(3)BE42, Complementation group 2, l(3)C2, l(3)BE43" 16-Dec-15 2015_12 "lethal,recessive" FBgn0022951 36w 36w http://flybase.net/reports/FBgn0022951.html gene 16-Dec-15 2015_12 "female sterile,partially" FBgn0033320 CG8586 http://flybase.net/reports/FBgn0033320.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "c-SPH58, SPH58" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG8586 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" viable FBgn0060988 l(3)S027821b lethal (3) S027821b http://flybase.net/reports/FBgn0060988.html gene 0278/21 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011826 Pp2B-14D Protein phosphatase 2B at 14D http://flybase.net/reports/FBgn0011826.html "FBgn0005782, FBgn0005783, FBgn0015613" protein_coding_gene "0005515=protein binding, 0004723=calcium-dependent protein serine/threonine phosphatase activity, 0005516=calmodulin binding, 0016787=hydrolase activity, 0004722=protein serine/threonine phosphatase activity" "0007143=female meiotic division, 0007126=meiotic nuclear division, 0035220=wing disc development, 0006470=protein dephosphorylation, 0030431=sleep, 0045995=regulation of embryonic development" 0005955=calcineurin complex "canA, CG9842, PP2B, CnA, PpD33, D33, Protein phosphatase D33, Pp2B-14DF, CanA14D, calcineurin, Calcineurin, PP2B 14D, PP2B-14D, protein phosphatase from PCR fragment D33, Pp12-14D, DmPp2B-14D, Pp2B-14D/CaN, CnnA14D" "IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase" CG9842 16-Dec-15 2015_12 "ENSDARG00000004988,ENSDARG00000057456(zgc:158685)" "YML057W(CMP2),YLR433C(CNA1)" WBGene00006527(tax-6) "ENSXETG00000011160(PPP3CA),ENSXETG00000010644(PPP3CB),ENSXETG00000010528(PPP3CC)" "ENSMUSG00000028161(Ppp3ca),ENSMUSG00000021816(Ppp3cb)" "ENSG00000138814(PPP3CA),ENSG00000107758(PPP3CB),ENSG00000120910(PPP3CC)" " embryonic stage , larval stage--adult stage , embryonic stage | stage <6 " " embryonic peripheral nervous system

, central nervous system

, organism

" "partially lethal - majority die,germline clone,visible,size defective,lethal,female sterile,meiotic cell cycle defective,sleep defective,locomotor behavior defective,viable" "eye,ommatidium,wing vein,wing,posterior compartment,wing blade,eye photoreceptor cell,photoreceptor cell R7,photoreceptor cell R3,photoreceptor cell R4,interommatidial bristle,egg & nuclear chromosomenos.UTR.THsimVP16,egg & spindlenos.UTR.THsimVP16,oocyte & nuclear chromatinnos.UTR.THsimVP16,oocyte & nucleusnos.UTR.THsimVP16" DRSC20270 EK -0.657160719 -0.936395856 2.226963277 1.767199934 -1.635530198 0.640051797 FBgn0038180 Cht5 Cht5 http://flybase.net/reports/FBgn0038180.html protein_coding_gene "0004568=chitinase activity, 0008061=chitin binding" "0006032=chitin catabolic process, 0005975=carbohydrate metabolic process" 0005615=extracellular space "chitin-binding peritrophin-A, DmCHT5, CG9307" "IPR001579=Glycoside hydrolase, chitinase active site, IPR002557=Chitin binding domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR011583=Chitinase II, IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain" CG9307 16-Dec-15 2015_12 YDR371W(CTS2) "ENSXETG00000011839(chia),ENSXETG00000011842(Q5CZZ2_XENTR),ENSXETG00000011844(chi)" "viable,fertile" FBgn0043047 anon-60Af anon-60Af http://flybase.net/reports/FBgn0043047.html gene 16-Dec-15 2015_12 FBgn0038845 CG10827 http://flybase.net/reports/FBgn0038845.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR018299=Alkaline phosphatase, active site, IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase" CG10827 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSMUSG00000028766(Alpl),ENSMUSG00000026246(Alppl2),ENSMUSG00000079440(Alpi),ENSMUSG00000036500(Akp3)" viable DRSC14269 K 0.578620853 -0.366896562 0.056720263 -0.118483537 1.949854475 0.036920914 FBgn0015357 anon-9Ba anon-9Ba http://flybase.net/reports/FBgn0015357.html gene 16-Dec-15 2015_12 FBgn0069937 CG41107 http://flybase.net/reports/FBgn0069937.html FBan0041107 protein_coding_gene 16-Dec-15 2015_12 FBgn0035158 CG13895 http://flybase.net/reports/FBgn0035158.html protein_coding_gene 0003677=DNA binding "IPR007889=DNA binding HTH domain, Psq-type, IPR009057=Homeodomain-like, IPR006600=HTH CenpB-type DNA-binding domain" CG13895 16-Dec-15 2015_12 "ENSMUSG00000044390(Tigd3),ENSMUSG00000047819(Tigd4),ENSMUSG00000068267(Cenpb)" "ENSG00000173825(TIGD3),ENSG00000169989(TIGD4)" viable FBgn0052651 CG32651 http://flybase.net/reports/FBgn0052651.html protein_coding_gene CG32651 16-Dec-15 2015_12 FBgn0030183 CG15309 http://flybase.net/reports/FBgn0030183.html FBgn0046798 protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis BcDNA:GH10478 IPR004910=Yippee/Mis18 CG15309 16-Dec-15 2015_12 "ENSDARG00000035630(ypel1),ENSDARG00000055510(ypel3)" YBL049W(MOH1) WBGene00009503(F37A8.5) "ENSXETG00000026188(ypel1),ENSXETG00000024940()" "ENSMUSG00000018427(Ypel2),ENSMUSG00000042675(Ypel3),ENSMUSG00000034059(Ypel4)" "ENSG00000175155(YPEL2),ENSG00000100027(YPEL1),ENSG00000090238(YPEL3),ENSG00000166793(YPEL4)" viable FBgn0069931 CG41120 http://flybase.net/reports/FBgn0069931.html FBan0041120 protein_coding_gene 16-Dec-15 2015_12 FBgn0031996 CG8460 http://flybase.net/reports/FBgn0031996.html protein_coding_gene 0004568=chitinase activity "0006032=chitin catabolic process, 0005975=carbohydrate metabolic process" 0012505=endomembrane system "IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR011583=Chitinase II, IPR017853=Glycoside hydrolase superfamily, IPR013781=Glycoside hydrolase, catalytic domain" CG8460 16-Dec-15 2015_12 "ENSDARG00000038289,ENSDARG00000069673(chid1)" "WBGene00016642(C44C1.2),WBGene00019980(R09B5.12)" ENSXETG00000019071(BC081307.1) ENSMUSG00000025512(Chid1) ENSG00000177830(CHID1) FBgn0016851 l(1)N32 lethal (1) N32 http://flybase.net/reports/FBgn0016851.html gene N32 16-Dec-15 2015_12 "lethal,recessive" FBgn0014267 l(2)k08225 lethal (2) k08225 http://flybase.net/reports/FBgn0014267.html gene 0007446=imaginal disc growth l(2)82/25 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,brain" FBgn0028888 CG4168 http://flybase.net/reports/FBgn0028888.html protein_coding_gene 0004930=G-protein coupled receptor activity "BG:DS03192.2, chaoptic-like" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG4168 16-Dec-15 2015_12 WBGene00016974(C56E6.6) FBgn0067638 wey weyprecht http://flybase.net/reports/FBgn0067638.html gene "0045451=pole plasm oskar mRNA localization, 0045450=bicoid mRNA localization" 16-Dec-15 2015_12 female sterile "follicle cell,germline clone" FBgn0010185 tu(3)1b tu(3)1b http://flybase.net/reports/FBgn0010185.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,partially lethal - majority die,some die during larval stage" FBgn0020267 n-judah n-judah http://flybase.net/reports/FBgn0020267.html gene 16-Dec-15 2015_12 FBgn0002140 l(2)K305 lethal (2) K305 http://flybase.net/reports/FBgn0002140.html gene 16-Dec-15 2015_12 lethal FBgn0263619 CR43628 http://flybase.net/reports/FBgn0263619.html non_protein_coding_gene CR43628 16-Dec-15 2015_12 FBgn0063924 Kaz1-ORFA Kaz1-ORFA http://flybase.net/reports/FBgn0063924.html "FBgn0026414, FBgn0053790, FBtr0072488, FBpp0072390, FBtr0072489, FBpp0072391, FBtr0072490, FBpp0072392, FBtr0072491, FBpp0072393, FBtr0072492, FBpp0072394, FBtr0072493, FBpp0072395, FBtr0072494, FBpp0072396" pseudogene_attribute "CR33790, ORF A, Kaz1, KAZ1 type alpha, CG33790, CG33045, Kaz1-ORF A" CR33790 16-Dec-15 2015_12 DRSC08669 K 0.326169449 0.057840784 0.010269493 0.222864967 -1.951156028 -0.47099077 FBgn0053639 CG33639 http://flybase.net/reports/FBgn0053639.html "FBgn0030901, FBgn0030902, FBgn0046535, FBgn0046536" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "CG5936, anon-WO0170980.40, CG16958, anon-WO0170980.41" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG33639 16-Dec-15 2015_12 WBGene00015263(B0563.6) viable DRSC22820 EK 0.587255647 1.492565 -2.488665965 0.112975947 0.756068648 1.91784939 FBgn0000863 fs(1)M57 female sterile (1) M57 http://flybase.net/reports/FBgn0000863.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,maternal effect,chorion | maternal effect" FBgn0264468 CR43876 http://flybase.net/reports/FBgn0264468.html non_protein_coding_gene CR43876 16-Dec-15 2015_12 FBgn0038889 Fancm Fanconi anemia group M helicase http://flybase.net/reports/FBgn0038889.html protein_coding_gene "0004386=helicase activity, 0043138=3'-5' DNA helicase activity, 0003677=DNA binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0045003=double-strand break repair via synthesis-dependent strand annealing, 0000725=recombinational repair, 0035825=reciprocal DNA recombination, 0006281=DNA repair" 0005634=nucleus "CG7922, cg7922, Fanconi anemia group M (FANCM) helicase" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR006935=Helicase/UvrB, N-terminal, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG7922 16-Dec-15 2015_12 ENSMUSG00000055884(Fancm) ENSG00000187790(FANCM) FBgn0261358 CG42635 http://flybase.net/reports/FBgn0261358.html "FBgn0032659, FBan0015149" protein_coding_gene CG15149 CG42635 16-Dec-15 2015_12 viable FBgn0065816 l(2)SH0378 lethal (2) SH0378 http://flybase.net/reports/FBgn0065816.html gene l(2)SH2 0378 16-Dec-15 2015_12 "lethal,recessive" FBgn0025742 mtm myotubularin http://flybase.net/reports/FBgn0025742.html protein_coding_gene "0005515=protein binding, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0004438=phosphatidylinositol-3-phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0009611=response to wounding, 0030031=cell projection assembly, 0016311=dephosphorylation, 0000278=mitotic cell cycle, 0030866=cortical actin cytoskeleton organization, 0006470=protein dephosphorylation, 0032456=endocytic recycling, 0007059=chromosome segregation" "0016020=membrane, 0005938=cell cortex" "dMTMH1, unnamed, Myotubularin, CG9115, MTM1" "IPR004182=GRAM domain, IPR010569=Myotubularin-like phosphatase domain, IPR030564=Myotubularin family, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site" CG9115 16-Dec-15 2015_12 "ENSDARG00000004616(mtmr2),ENSDARG00000056690(mtmr1a),ENSDARG00000022378(mtmr1b),ENSDARG00000037560(mtm1)" YJR110W(YMR1) WBGene00003475(mtm-1) "ENSXETG00000017786(mtm1),ENSXETG00000007741(mtmr1),ENSXETG00000007082(MTMR2)" "ENSMUSG00000031918(Mtmr2),ENSMUSG00000015214(Mtmr1),ENSMUSG00000031337(Mtm1)" "ENSG00000087053(MTMR2),ENSG00000063601(MTMR1),ENSG00000171100(MTM1)" "lethal - all die before end of larval stage,some die during third instar larval stage,wound healing defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,majority die during pupal stage,developmental rate defective,flightless,viable" "embryonic/larval hemocyte,sessile hemocyte,abdominal temporary eclosion muscle DA,temporary eclosion muscle,testis sheath muscle,T-tubuleMef2.PR,macrophage" FBgn0259703 CG42357 http://flybase.net/reports/FBgn0259703.html "FBan0032308, FBgn0052308" protein_coding_gene CG32308 CG42357 16-Dec-15 2015_12 FBgn0262996 CR43304 http://flybase.net/reports/FBgn0262996.html non_protein_coding_gene CR43304 16-Dec-15 2015_12 FBgn0019773 l(1)38 lethal (1) 38 http://flybase.net/reports/FBgn0019773.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033257 CG8713 http://flybase.net/reports/FBgn0033257.html "FBgn0043918, FBgn0043922, FBgn0043923, FBgn0043924, FBgn0043925, FBgn0043926, FBgn0043927, FBgn0043928, FBgn0043929" protein_coding_gene "0005267=potassium channel activity, 0005250=A-type (transient outward) potassium channel activity" 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "anon-WO0109301.45, anon-WO0109301.5, anon-WO0109301.39, anon-WO0109301.42, anon-WO0109301.43, anon-WO0109301.46, anon-WO0109301.40, anon-WO0109301.41, anon-WO0109301.44" "IPR013099=Potassium channel domain, IPR003280=Two pore domain potassium channel" CG8713 16-Dec-15 2015_12 WBGene00006690(twk-39) ENSXETG00000004192(KCNK18) "viable,fertile" FBgn0083054 snoRNA:ë¬18S-1347a snoRNA:ë¬18S-1347a http://flybase.net/reports/FBgn0083054.html snoRNA_gene "Psi18S-1347a, psi18S-1347a, Psi 18S-1347a(SnoR203), CR34544" CR34544 16-Dec-15 2015_12 FBgn0267098 CR45538 http://flybase.net/reports/FBgn0267098.html non_protein_coding_gene CR45538 16-Dec-15 2015_12 FBgn0032588 CG5968 http://flybase.net/reports/FBgn0032588.html FBgn0063297 protein_coding_gene BcDNA:AT27976 CG5968 16-Dec-15 2015_12 viable FBgn0003491 sps spastic http://flybase.net/reports/FBgn0003491.html gene 16-Dec-15 2015_12 "lethal,sterile,uncoordinated,behavior defective" FBgn0041782 S(Sev-CycE)D30 S(Sev-CycE)D30 http://flybase.net/reports/FBgn0041782.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035679 CG10467 http://flybase.net/reports/FBgn0035679.html protein_coding_gene "0030246=carbohydrate binding, 0004034=aldose 1-epimerase activity" 0019318=hexose metabolic process 0005576=extracellular region "IPR014718=Glycoside hydrolase-type carbohydrate-binding, subgroup, IPR008183=Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR018052=Aldose 1-epimerase, conserved site, IPR015443=Aldose 1-epimerase, IPR011013=Galactose mutarotase-like domain" CG10467 16-Dec-15 2015_12 ENSDARG00000057630(galm) "YHR210C(),YNR071C()" WBGene00015270(C01B4.6) ENSXETG00000009022(GALM) ENSMUSG00000035473(Galm) ENSG00000143891(GALM) viable DRSC09728 K 0.066956422 0.007044745 -0.526193059 0.660274526 -0.613578298 2.165825822 FBgn0001750 l(1)HM22 lethal (1) HM22 http://flybase.net/reports/FBgn0001750.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0001370 l(1)2Ac lethal (1) 2Ac http://flybase.net/reports/FBgn0001370.html FBgn0001368 gene l(1)2Aa 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085661 CG41511 http://flybase.net/reports/FBgn0085661.html FBan0041511 protein_coding_gene 16-Dec-15 2015_12 FBgn0042691 Su(Ste)OR Suppressor of Stellate orphon http://flybase.net/reports/FBgn0042691.html pseudogene_attribute SuSteOR 16-Dec-15 2015_12 FBgn0004107 Cdk2 Cyclin-dependent kinase 2 http://flybase.net/reports/FBgn0004107.html protein_coding_gene "0005524=ATP binding, 0004693=cyclin-dependent protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" "0000082=G1/S transition of mitotic cell cycle, 0000086=G2/M transition of mitotic cell cycle, 0007259=JAK-STAT cascade, 0051726=regulation of cell cycle, 0006468=protein phosphorylation" 0005875=microtubule associated complex "dCdk2, Cyclin E, cyclin E-CDK2, cdk2, Cdc2c, DmCdk2, Cdk2, CDC2C, S(Sev-CycE)3A, Dmcdc2c, cyclin-dependent kinase 2, CG10498, CDK2, CDK2/CDC2c, DmCdc2, Dcdc2c, cdc2c, CDC2c" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG10498 16-Dec-15 2015_12 ENSDARG00000026577(cdk2) ENSXETG00000009444(cdk2) "ENSMUSG00000034288,ENSMUSG00000025358(Cdk2)" "ENSG00000123374(CDK2),ENSG00000108504" " embryonic stage | early , embryonic stage " embryonic central nervous system

"small body,lethal,recessive,wild-type" larval outer optic anlage DRSC16921 IEK -1.417489246 -1.755788586 -2.638859898 -3.688672595 4.262878723 4.709982217 FBgn0035268 CG8001 http://flybase.net/reports/FBgn0035268.html protein_coding_gene "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG8001 16-Dec-15 2015_12 ENSDARG00000000324(LOC100007924) ENSXETG00000008121(wdr42a) "ENSMUSG00000026554(Dcaf8),ENSMUSG00000035395(Pet2)" "ENSG00000132716(DCAF8),ENSG00000189186" viable FBgn0030340 CG15740 http://flybase.net/reports/FBgn0030340.html protein_coding_gene i175 CG15740 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC23079 K 3.84774172 -0.800226233 FBgn0050389 CG30389 http://flybase.net/reports/FBgn0050389.html "FBgn0034596, FBgn0034597, FBgn0065029" protein_coding_gene 0016021=integral component of membrane "CG4126, BcDNA:AT02070, CG10518" IPR019130=Macoilin CG30389 16-Dec-15 2015_12 "ENSDARG00000012741(tmem57b),ENSDARG00000005625(tmem57a),ENSDARG00000056092" WBGene00017066(D2092.5) ENSMUSG00000028826(Tmem57) ENSG00000204178(TMEM57) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0000282 cel celibate http://flybase.net/reports/FBgn0000282.html gene "0008049=male courtship behavior, 0007620=copulation" 16-Dec-15 2015_12 "viable,mating defective,male" FBgn0032717 CG10600 http://flybase.net/reports/FBgn0032717.html protein_coding_gene 0005634=nucleus IPR026306=Round spermatid basic protein 1 CG10600 16-Dec-15 2015_12 "ENSXETG00000013190(RSBN1),ENSXETG00000019725(rsbn1l)" "ENSMUSG00000044098(Rsbn1),ENSMUSG00000039968(Rsbn1l)" "ENSG00000187257(RSBN1L),ENSG00000081019(RSBN1)" "viable,fertile" FBgn0052532 CG32532 http://flybase.net/reports/FBgn0052532.html "FBgn0031027, FBgn0031028, FBgn0031029" protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG14203, CG14201, CG14202" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG32532 16-Dec-15 2015_12 ENSXETG00000021832(ARX) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC19556 K 0.405889417 0.556868105 -0.462647501 0.559554584 -0.317812098 -1.51757777 FBgn0263565 mir-4950 mir-4950 stem loop http://flybase.net/reports/FBgn0263565.html miRNA_gene "CR43550, dme-mir-4950" CR43550 16-Dec-15 2015_12 FBgn0028402 Sin Sex-lethal interactor http://flybase.net/reports/FBgn0028402.html protein_coding_gene "0005515=protein binding, 0003899=DNA-directed RNA polymerase activity" "0006351=transcription, DNA-templated" 0005634=nucleus "sin, CG10582" IPR006886=DNA-directed RNA polymerase III subunit Rpc5 CG10582 16-Dec-15 2015_12 ENSDARG00000037358(polr3e) WBGene00021061(W06E11.1) "ENSXETG00000016663(TEgg080g07.1),ENSXETG00000027586(polr3e)" ENSMUSG00000030880(Polr3e) ENSG00000058600(POLR3E) " embryonic stage , embryonic stage | early "

ubiquitous lethal DRSC11880 E -0.669581338 0.830418859 -2.141370535 -0.50721451 -0.784533209 -0.254867776 FBgn0039196 CG17781 http://flybase.net/reports/FBgn0039196.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG17781 16-Dec-15 2015_12 DRSC15266 K 0.33721108 -0.132658862 -0.140628841 0.289813216 0.079074587 2.121301381 FBgn0036454 CG17839 http://flybase.net/reports/FBgn0036454.html protein_coding_gene 0005634=nucleus "CT39634, 17839" "IPR013783=Immunoglobulin-like fold, IPR002602=Domain of unknown function DB, IPR013151=Immunoglobulin, IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR003599=Immunoglobulin subtype" CG17839 16-Dec-15 2015_12 "WBGene00007736(C25G4.10),WBGene00011418(T04A11.3)" "viable,fertile" FBgn0033807 AQP aquaporin http://flybase.net/reports/FBgn0033807.html protein_coding_gene 0005372=water transmembrane transporter activity 0006833=water transport "CG12251, AQP-dr" "IPR023271=Aquaporin-like, IPR016697=Aquaporin 11/12, IPR031145=Invertebrate aquaporin-10" CG12251 16-Dec-15 2015_12 "ENSDARG00000043279(aqp12),ENSDARG00000042617(aqp11)" WBGene00000177(aqp-9) "ENSMUSG00000045091(Aqp12),ENSMUSG00000042797(Aqp11)" "ENSG00000185176(AQP12B),ENSG00000184945(AQP12A)" FBgn0261729 EC1608 http://flybase.net/reports/FBgn0261729.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030654 CG15643 http://flybase.net/reports/FBgn0030654.html FBgn0052583 protein_coding_gene CG32583 IPR019352=Uncharacterised protein family UPF0454 CG15643 16-Dec-15 2015_12 ENSDARG00000053013(zgc:110063) ENSXETG00000028044(C12orf49) ENSMUSG00000032840(2410131K14Rik) ENSG00000111412(C12orf49) FBgn0038127 CG8476 http://flybase.net/reports/FBgn0038127.html protein_coding_gene IPR001623=DnaJ domain CG8476 16-Dec-15 2015_12 WBGene00001022(dnj-4) "ENSMUSG00000026203(Dnajb2),ENSMUSG00000029131(Dnajb6),ENSMUSG00000048206(Dnajb8),ENSMUSG00000081984(Dnajb3),ENSMUSG00000047108(Dnajb7)" FBgn0014403 vcg ventral central gaps http://flybase.net/reports/FBgn0014403.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "longitudinal connective,commissure,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt" FBgn0051687 CG31687 http://flybase.net/reports/FBgn0051687.html protein_coding_gene "0090175=regulation of establishment of planar polarity, 0030071=regulation of mitotic metaphase/anaphase transition" 0005680=anaphase-promoting complex CG31687-PA "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR007192=Cdc23" CG31687 16-Dec-15 2015_12 ENSDARG00000044484(cdc23) YHR166C(CDC23) WBGene00003134(mat-3) ENSXETG00000006716(cdc23) ENSMUSG00000024370(Cdc23) ENSG00000094880(CDC23) planar polarity defective "ommatidium,wing hair,supernumerary" FBgn0053512 dpr4 defective proboscis extension response 4 http://flybase.net/reports/FBgn0053512.html "FBgn0037909, FBgn0040548, FBtr0082468, FBpp0081944, FBtr0082469, FBpp0081945" protein_coding_gene 0007606=sensory perception of chemical stimulus "Dpr-4, CG12593, dpr4, CT34497, CG33512, Dpr4, CG14707" "IPR013783=Immunoglobulin-like fold, IPR013151=Immunoglobulin, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2" CG33512 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) viable FBgn0001238 hv heavy vein http://flybase.net/reports/FBgn0001238.html gene heavy-vein 16-Dec-15 2015_12 visible "wing vein,crossvein,wing,eye,posterior scutellar bristle" FBgn0065777 l(2)SH0449 lethal (2) SH0449 http://flybase.net/reports/FBgn0065777.html gene l(2)SH2 0449 16-Dec-15 2015_12 "lethal,recessive" FBgn0017558 Pdk Pyruvate dehydrogenase kinase http://flybase.net/reports/FBgn0017558.html FBgn0062465 protein_coding_gene "0004672=protein kinase activity, 0004740=pyruvate dehydrogenase (acetyl-transferring) kinase activity" 0006090=pyruvate metabolic process 0005759=mitochondrial matrix "CG8808, DmPDK, pyruvate dehydrogenase kinase, PDK, DmPdk, BcDNA:LD09837, pdk" "IPR018955=Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal, IPR005467=Histidine kinase domain, IPR003594=Histidine kinase-like ATPase, C-terminal domain" CG8808 16-Dec-15 2015_12 "ENSDARG00000013128(LOC555840),ENSDARG00000054848(si:rp71-57j15.4),ENSDARG00000020876(LOC794083),ENSDARG00000059054(pdk2),ENSDARG00000054489,ENSDARG00000014527(pdk3a)" YIL042C(PKP1) WBGene00022719(pdhk-2) "ENSXETG00000021812(PDK3),ENSXETG00000020289(pdk2),ENSXETG00000007526(PDK1)" "ENSMUSG00000035232(Pdk3),ENSMUSG00000006494(Pdk1),ENSMUSG00000038967(Pdk2),ENSMUSG00000019577(Pdk4)" "ENSG00000067992(PDK3),ENSG00000005882(PDK2),ENSG00000152256(PDK1),ENSG00000004799(PDK4)" " adult stage | female , embryonic stage | 0-20 hr , pupal stage , adult stage | male , larval stage | third instar , embryonic stage "

ubiquitous "viable,fertile" FBgn0065721 l(2)SH0569 lethal (2) SH0569 http://flybase.net/reports/FBgn0065721.html gene l(2)SH2 0569 16-Dec-15 2015_12 "lethal,recessive" FBgn0005448 l(1)v223 lethal (1) v223 http://flybase.net/reports/FBgn0005448.html gene l(1)223 16-Dec-15 2015_12 FBgn0039131 CG12268 http://flybase.net/reports/FBgn0039131.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding, IPR016040=NAD(P)-binding domain" CG12268 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263771 CR43688 http://flybase.net/reports/FBgn0263771.html pseudogene_attribute CR43688 16-Dec-15 2015_12 FBgn0083167 Neb-cGP Neb-cGP http://flybase.net/reports/FBgn0083167.html "FBgn0040943, FBgn0047010, FBgn0047119" protein_coding_gene 0005179=hormone activity 0040008=regulation of growth 0005615=extracellular space "BcDNA:RH45340, putative noncoding RNA 006:X, CG15304, BcDNA:RE31692, pncr006:X" IPR009125=DAPIT CG15304 16-Dec-15 2015_12 ENSMUSG00000071528(Usmg5) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0000056 Adhr Adh-related http://flybase.net/reports/FBgn0000056.html "FBgn0052954, FBtr0080648, FBpp0080216, FBtr0080649, FBpp0080217, FBtr0080650, FBpp0080218, FBtr0080651, FBpp0080219, FBtr0080652, FBpp0080220, FBtr0080653, FBpp0080221, FBtr0080654, FBpp0080222, FBtr0080655, FBpp0080223" protein_coding_gene "0004022=alcohol dehydrogenase (NAD) activity, 0051287=NAD binding" 0055114=oxidation-reduction process "unnamed, CG32954, ADHR, 3'ORF, alcohol dehydrogenase related, BG:DS01486.9, Adh[r], Adh-dup, Adh related, CG3484, ADH[r]" "IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002424=Alcohol dehydrogenase, insect-type, IPR002427=Alcohol dehydrogenase-related, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG3484 16-Dec-15 2015_12 "ENSDARG00000026236(zgc:56585),ENSDARG00000012016(LOC565975)" ENSXETG00000016904(hpgd) FBgn0041180 Tep4 Thioester-containing protein 4 http://flybase.net/reports/FBgn0041180.html FBgn0032806 protein_coding_gene "0030414=peptidase inhibitor activity, 0004866=endopeptidase inhibitor activity" "0009620=response to fungus, 0032504=multicellular organism reproduction, 0019731=antibacterial humoral response" 0005615=extracellular space "CT29102, CG10363, TEP IV, tep4, dTEPIV, Tep IV, tepIV, TEP4, TepIV, Tep4, TEP, TEP4mel, TEPIV, Thioester containing protein IV, Thiolester containing protein IV" "IPR002890=Alpha-2-macroglobulin, N-terminal, IPR001599=Alpha-2-macroglobulin, IPR014756=Immunoglobulin E-set, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR011626=Alpha-macroglobulin complement component, IPR009048=Alpha-macroglobulin, receptor-binding, IPR019565=Alpha-2-macroglobulin, thiol-ester bond-forming, IPR011625=Alpha-2-macroglobulin, N-terminal 2, IPR019742=Alpha-2-macroglobulin, conserved site" CG10363 16-Dec-15 2015_12 "ENSDARG00000056314(a2ml),ENSDARG00000041645(sb:cb37),ENSDARG00000041685(LOC100006782),ENSDARG00000056588,ENSDARG00000024892,ENSDARG00000017289,ENSDARG00000017619,ENSDARG00000041639,ENSDARG00000035291,ENSDARG00000053178,ENSDARG00000027924,ENSDARG00000035292,ENSDARG00000041653,ENSDARG00000058274,ENSDARG00000008835" WBGene00013969(ZK337.1) "ENSXETG00000024219(BC093458.1),ENSXETG00000024227(),ENSXETG00000017070(),ENSXETG00000006980(BC091705.1),ENSXETG00000006979(),ENSXETG00000009402(),ENSXETG00000017401(),ENSXETG00000009400()" ENSMUSG00000046186(Cd109) ENSG00000156535(CD109) viable FBgn0058114 CG40114 http://flybase.net/reports/FBgn0058114.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032620 CG12288 http://flybase.net/reports/FBgn0032620.html protein_coding_gene "0008143=poly(A) binding, 0000166=nucleotide binding, 0003729=mRNA binding" 0005875=microtubule associated complex cg12288 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG12288 16-Dec-15 2015_12 ENSDARG00000022728(rbm34) YOL041C(NOP12) WBGene00008688(F11A10.7) ENSXETG00000023721(BC075294.1) ENSMUSG00000033931(Rbm34) ENSG00000188739(RBM34) FBgn0002831 ms(2)E10 male sterile (2) E10 http://flybase.net/reports/FBgn0002831.html gene "ms2.10, ms(2)2.10" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0051347 CG31347 http://flybase.net/reports/FBgn0051347.html protein_coding_gene CG31347 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0265343 CR44297 http://flybase.net/reports/FBgn0265343.html non_protein_coding_gene CR44297 16-Dec-15 2015_12 FBgn0264789 CR44019 http://flybase.net/reports/FBgn0264789.html non_protein_coding_gene CR44019 16-Dec-15 2015_12 FBgn0263846 CG43707 http://flybase.net/reports/FBgn0263846.html "FBgn0051959, FBgn0031569, FBgn0051772" protein_coding_gene "CG31772, CG10020, CG31959" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001478=PDZ domain" CG43707 16-Dec-15 2015_12 DRSC22912 K 0.241260386 0.144499459 -0.050174664 1.316653047 1.547089255 0.20151277 FBgn0035107 mri mrityu http://flybase.net/reports/FBgn0035107.html protein_coding_gene 0004370=glycerol kinase activity "0046331=lateral inhibition, 0035071=salivary gland cell autophagic cell death, 0050975=sensory perception of touch, 0048102=autophagic cell death" "Mri, Mrityu, CG1216" "IPR000210=BTB/POZ domain, IPR011333=POZ domain" CG1216 16-Dec-15 2015_12 "ENSDARG00000020252,ENSDARG00000062674(btbd10a),ENSDARG00000059381" WBGene00019888(R05F9.1) ENSXETG00000024203(BTBD10) "ENSMUSG00000038187(Btbd10),ENSMUSG00000005936(Kctd20)" "ENSG00000148925(BTBD10),ENSG00000112078(KCTD20)" "viable,visible,neuroanatomy defective,touch sensitivity defective" "chaeta,supernumerary,mesothoracic tergum,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0019743 l(1)8E lethal (1) 8E http://flybase.net/reports/FBgn0019743.html gene l(1)8 16-Dec-15 2015_12 "lethal,recessive" FBgn0265382 CR44323 http://flybase.net/reports/FBgn0265382.html non_protein_coding_gene CR44323 16-Dec-15 2015_12 FBgn0030572 mRpS25 mitochondrial ribosomal protein S25 http://flybase.net/reports/FBgn0030572.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "CG14413, MrpS25, Mitochondrial ribosomal protein S25, 25mRps, MRP-S25" "IPR007741=Ribosomal protein/NADH dehydrogenase domain, IPR012336=Thioredoxin-like fold" CG14413 16-Dec-15 2015_12 ENSDARG00000041306(mrps25) WBGene00021920(Y55F3AM.1) "ENSXETG00000004816(),ENSXETG00000000318()" ENSMUSG00000014551(Mrps25) ENSG00000131368(MRPS25) "viable,visible" trichogen cell FBgn0022006 l(2)k09221 lethal (2) k09221 http://flybase.net/reports/FBgn0022006.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011611 l(1)I33e16 lethal (1) I33e16 http://flybase.net/reports/FBgn0011611.html FBgn0010206 gene l(1)33e16 16-Dec-15 2015_12 lethal FBgn0020359 anon-1H11 anon-1H11 http://flybase.net/reports/FBgn0020359.html gene 1H11 16-Dec-15 2015_12 FBgn0015543 snoRNA:Me28S-A1322 http://flybase.net/reports/FBgn0015543.html snoRNA_gene 0030555=RNA modification guide activity 0005730=nucleolus "Me28S-A1322(Z1), SnR61, CR32905, snoR797, chr2R:7409020..7409115, Z1, snoRNA Z1, snoRNA:Z1, DmSnR61c, Dm-797" CR32905 16-Dec-15 2015_12 FBgn0041159 dos::Hsap\GAB1 GAB1 http://flybase.net/reports/FBgn0041159.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0013447 fs(2)ry11 fs(2)ry11 http://flybase.net/reports/FBgn0013447.html gene "unnamed, fs(2)11" 16-Dec-15 2015_12 "female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0085237 CG34208 http://flybase.net/reports/FBgn0085237.html protein_coding_gene CG34208 16-Dec-15 2015_12 FBgn0002055 l(2)38Aa lethal (2) 38Aa http://flybase.net/reports/FBgn0002055.html gene l(2)E124P 16-Dec-15 2015_12 lethal FBgn0017407 diva divagari http://flybase.net/reports/FBgn0017407.html gene "0007411=axon guidance, 0007420=brain development" 16-Dec-15 2015_12 "viable,male sterile" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor,larval inner optic anlage,larval outer optic anlage" FBgn0051457 CG31457 http://flybase.net/reports/FBgn0051457.html FBgn0039057 protein_coding_gene "0008157=protein phosphatase 1 binding, 0008270=zinc ion binding" 0005634=nucleus CG4639 "IPR012934=Zinc finger, AD-type" CG31457 16-Dec-15 2015_12 viable FBgn0011582 Dop1R1 Dopamine 1-like receptor 1 http://flybase.net/reports/FBgn0011582.html protein_coding_gene "0001588=dopamine neurotransmitter receptor activity, coupled via Gs, 0004930=G-protein coupled receptor activity, 0004952=dopamine neurotransmitter receptor activity" "0008306=associative learning, 0090328=regulation of olfactory learning, 0008355=olfactory learning, 0071329=cellular response to sucrose stimulus, 0007212=dopamine receptor signaling pathway, 0040040=thermosensory behavior, 0009744=response to sucrose, 0007191=adenylate cyclase-activating dopamine receptor signaling pathway, 0007613=memory, 0007612=learning, 0042594=response to starvation, 0043052=thermotaxis" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "D-Dop1, DmDop1, dDA1/DmDOP1, DopR1, D1 dopamine receptor, dopamine D1-like receptor, D[[1]] dopamine receptor, D1-Like Dopamine Receptor, dumb DA receptor, Dmdop1, DA1, dopamine D1 receptor, dopamine 1 receptor, Dopamine receptor, dDA1, dumb, dopamine receptor, DmDOP1, DopR, D1-like DA receptor, CG9652, DR1, DA D[[1]]-like receptor, DopR35F, D1-like receptor" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000929=Dopamine receptor family, IPR000276=G protein-coupled receptor, rhodopsin-like" CG9652 16-Dec-15 2015_12 "ENSDARG00000040765(LOC100001636),ENSDARG00000024873,ENSDARG00000038918(drd1),ENSDARG00000056284(LOC100002285),ENSDARG00000071640(LOC792634),ENSDARG00000054469,ENSDARG00000037576" WBGene00001052(dop-1) "ENSXETG00000020979(),ENSXETG00000026496(DRD5),ENSXETG00000013921(DRD1)" "ENSMUSG00000039358(Drd5),ENSMUSG00000021478(Drd1a)" "ENSG00000184845(DRD1),ENSG00000169676(DRD5)" "learning defective,flight defective,lethal,some die during immature adult stage,recessive,partially lethal - majority die,male,courtship behavior defective,memory defective,viable,fertile,hyperactive,chemical conditional,hypoactive,thermotaxis behavior defective" DRSC16652 IE -0.728094939 -2.102660702 -0.146151673 -2.955447966 0.544773039 0.55029531 FBgn0086678 fs(3)H813 http://flybase.net/reports/FBgn0086678.html gene H813 16-Dec-15 2015_12 "female sterile,recessive" FBgn0039860 CG1792 http://flybase.net/reports/FBgn0039860.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG1792 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "viable,fertile" FBgn0061474 28SrRNA 28SrRNA http://flybase.net/reports/FBgn0061474.html "FBgn0045782, FBgn0045792, FBgn0045793, FBgn0045794, FBgn0045992, FBgn0046040, FBgn0046048, FBgn0046072" rRNA_gene 0022625=cytosolic large ribosomal subunit "28s rRNA, NEST:bs10c09, 28S, 28S rRNA, 28S RNA, BEST:HL02977, NEST:bs17g11, NEST:bs15g08, 28SRNA, BEST:LD41653, 28S rDNA, BEST:HL03427, 28S ribosomal RNA, Mgn570, unnamed, NEST:bs30g02, BEST:HL02093, 28S DNA" 16-Dec-15 2015_12 FBgn0016068 slbo::Rat\C-EBP-ë« C-EBP-ë« http://flybase.net/reports/FBgn0016068.html engineered_fusion_gene slbo::Rat\C/EBP-delta 16-Dec-15 2015_12 FBgn0020796 oculi-rugosissimi oculi rugosissimi http://flybase.net/reports/FBgn0020796.html gene "occhi rugosissimi, or, oculi-rufosissimi" 16-Dec-15 2015_12 "visible,viable" ommatidium FBgn0039130 CG5854 http://flybase.net/reports/FBgn0039130.html FBgn0062107 protein_coding_gene "0003824=catalytic activity, 0050662=coenzyme binding" anon-WO0118547.306 "IPR001509=NAD-dependent epimerase/dehydratase, N-terminal domain, IPR016040=NAD(P)-binding domain" CG5854 16-Dec-15 2015_12 viable FBgn0036526 CG13450 http://flybase.net/reports/FBgn0036526.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035890 CG13667 http://flybase.net/reports/FBgn0035890.html protein_coding_gene "0005506=iron ion binding, 0003958=NADPH-hemoprotein reductase activity, 0016709=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, 0010181=FMN binding, 0016491=oxidoreductase activity" 0055114=oxidation-reduction process 0005829=cytosol "IPR029039=Flavoprotein-like, IPR023173=NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3, IPR003097=FAD-binding, type 1, IPR028879=NADPH-dependent diflavin oxidoreductase 1, IPR001094=Flavodoxin, IPR001709=Flavoprotein pyridine nucleotide cytochrome reductase, IPR017938=Riboflavin synthase-like beta-barrel, IPR008254=Flavodoxin/nitric oxide synthase, IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR001433=Oxidoreductase FAD/NAD(P)-binding" CG13667 16-Dec-15 2015_12 ENSDARG00000007429 YPR048W(TAH18) WBGene00001485(fre-1) ENSXETG00000022930(NDOR1) ENSMUSG00000006471(Ndor1) ENSG00000188566(NDOR1) viable FBgn0033177 CG11141 http://flybase.net/reports/FBgn0033177.html protein_coding_gene "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG11141 16-Dec-15 2015_12 ENSXETG00000010256(TECPR2) "viable,fertile,visible" trichogen cell FBgn0024259 acd(2)5N17 auditory courtship defective 5N17 http://flybase.net/reports/FBgn0024259.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0013687 mt:ori mitochondrial origin http://flybase.net/reports/FBgn0013687.html FBgn0002867 16-Dec-15 2015_12 FBgn0039796 CG12069 http://flybase.net/reports/FBgn0039796.html protein_coding_gene "0005524=ATP binding, 0004691=cAMP-dependent protein kinase activity, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation 0005952=cAMP-dependent protein kinase complex "PKA-like, Pka-like" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG12069 16-Dec-15 2015_12 "male sterile,viable" FBgn0011669 Mst57Db Male-specific RNA 57Db http://flybase.net/reports/FBgn0011669.html FBgn0002859 protein_coding_gene "0045297=post-mating behavior, 0032504=multicellular organism reproduction, 0018991=oviposition" "0005576=extracellular region, 0005615=extracellular space" "male specific transcript 57D, CG5016, mst(2)ag-1, mst-1" CG5016 16-Dec-15 2015_12 viable FBgn0050067 Obp50a Odorant-binding protein 50a http://flybase.net/reports/FBgn0050067.html FBgn0043528 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp50a, anon-AE003814.2, unnamed, CG30067" CG30067 16-Dec-15 2015_12 DRSC22152 K -0.432014595 0.335792788 -0.190516925 0.04012612 0.565493814 -2.486145714 FBgn0052723 CR32723 http://flybase.net/reports/FBgn0052723.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0260869 CG42579 http://flybase.net/reports/FBgn0260869.html protein_coding_gene HDC19846 CG42579 16-Dec-15 2015_12 FBgn0005160 l(2)G151 lethal (2) G151 http://flybase.net/reports/FBgn0005160.html gene 16-Dec-15 2015_12 lethal FBgn0014369 osho one shot http://flybase.net/reports/FBgn0014369.html gene 16-Dec-15 2015_12 FBgn0035141 Cypl Cyclophilin-like http://flybase.net/reports/FBgn0035141.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0048042=regulation of post-mating oviposition, 0006457=protein folding, 0000398=mRNA splicing, via spliceosome, 0000413=protein peptidyl-prolyl isomerization" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "cypl, CG13892, cycl" "IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain" CG13892 16-Dec-15 2015_12 ENSDARG00000015422(ppil1) WBGene00000888(cyn-12) ENSXETG00000017097(BC076653.1) ENSMUSG00000024007(Ppil1) ENSG00000137168(PPIL1) "viable,lethal" FBgn0061150 l(2)N113 lethal (2) N113 http://flybase.net/reports/FBgn0061150.html gene N113 16-Dec-15 2015_12 "lethal,recessive" FBgn0052694 CG32694 http://flybase.net/reports/FBgn0052694.html "FBgn0030168, FBgn0030169, FBgn0042223, FBgn0063079" protein_coding_gene 0005811=lipid particle "CG12634, BcDNA:RE02049, CG18512, CG12649" CG32694 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0011117 l(1)Q78 lethal (1) Q78 http://flybase.net/reports/FBgn0011117.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0267276 CR45712 http://flybase.net/reports/FBgn0267276.html non_protein_coding_gene CR45712 16-Dec-15 2015_12 FBgn0038385 Fbxl7 F-box and leucine-rich repeat protein 7 http://flybase.net/reports/FBgn0038385.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0007449=proximal/distal pattern formation, imaginal disc, 0045571=negative regulation of imaginal disc growth, 0045926=negative regulation of growth, 0016567=protein ubiquitination, 0044257=cellular protein catabolic process, 0035330=regulation of hippo signaling, 0032880=regulation of protein localization" "0005911=cell-cell junction, 0019005=SCF ubiquitin ligase complex, 0045177=apical part of cell" "FBXL7, FbxL7, CG4221" "IPR001810=F-box domain, IPR006553=Leucine-rich repeat, cysteine-containing subtype" CG4221 16-Dec-15 2015_12 ENSDARG00000062251(zgc:158346) YJR052W(RAD7) ENSXETG00000007541(FBXL7) ENSMUSG00000043556(Fbxl7) ENSG00000183580(FBXL7) "viable,fertile" FBgn0036945 Ssk Snakeskin http://flybase.net/reports/FBgn0036945.html protein_coding_gene "0019991=septate junction assembly, 0061028=establishment of endothelial barrier, 0007496=anterior midgut development, 0060576=intestinal epithelial cell development" "0005920=smooth septate junction, 0005887=integral component of plasma membrane" "CG6981, CT21613, ssk" CG6981 16-Dec-15 2015_12 "viable,partially lethal - majority die,lethal,locomotor behavior defective" "anterior embryonic/larval midgut,smooth septate junctionda.G32" FBgn0035259 CG13932 http://flybase.net/reports/FBgn0035259.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0262356 CG43054 http://flybase.net/reports/FBgn0262356.html protein_coding_gene lincRNA.173 CG43054 16-Dec-15 2015_12 FBgn0019695 l(2)k08601 lethal (2) k08601 http://flybase.net/reports/FBgn0019695.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0025921 l(3)78Ad lethal (3) 78Ad http://flybase.net/reports/FBgn0025921.html gene 16-Dec-15 2015_12 lethal FBgn0065453 l(2)SH1396 lethal (2) SH1396 http://flybase.net/reports/FBgn0065453.html gene l(2)SH2 1396 16-Dec-15 2015_12 "lethal,recessive" FBgn0085750 CR40581 http://flybase.net/reports/FBgn0085750.html FBan0040581 rRNA_gene CR40581 16-Dec-15 2015_12 FBgn0262791 CG43172 http://flybase.net/reports/FBgn0262791.html protein_coding_gene "noncoding_5744, nc_5744.a" CG43172 16-Dec-15 2015_12 FBgn0000204 bord bordered http://flybase.net/reports/FBgn0000204.html gene 16-Dec-15 2015_12 "viable,poor,visible,recessive" "wing,wing vein" FBgn0040688 CG12483 http://flybase.net/reports/FBgn0040688.html FBgn0062944 protein_coding_gene BcDNA:RH38463 CG12483 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0052984 CG32984 http://flybase.net/reports/FBgn0052984.html FBgn0032081 protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi22945998, gi21430910, CG17789" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG32984 16-Dec-15 2015_12 viable FBgn0029946 CG15034 http://flybase.net/reports/FBgn0029946.html protein_coding_gene CG15034 16-Dec-15 2015_12 viable FBgn0001280 janA janus A http://flybase.net/reports/FBgn0001280.html FBgn0063739 protein_coding_gene 0007548=sex differentiation "jan, janus, jan A, CG7933, Jan, Y, BcDNA:AT12574" IPR007702=Janus CG7933 16-Dec-15 2015_12 ENSDARG00000045567(phpt1) WBGene00009455(phip-1) "ENSXETG00000003946(),ENSXETG00000004740()" ENSMUSG00000036504(Phpt1) " adult stage | male , embryonic stage -- adult stage , larval stage--adult stage | male " organism

viable FBgn0039068 CG13827 http://flybase.net/reports/FBgn0039068.html FBgn0063037 protein_coding_gene "0016559=peroxisome fission, 0046331=lateral inhibition" "0005779=integral component of peroxisomal membrane, 0005777=peroxisome" "PEX11C, BcDNA:RE30473" "IPR008733=Peroxisomal biogenesis factor 11, IPR026510=Peroxisomal membrane protein 11C, metazoa" CG13827 16-Dec-15 2015_12 ENSDARG00000025559(zgc:114079) WBGene00004196(prx-11) ENSXETG00000001816(PEX11G) ENSMUSG00000069633(Pex11c) ENSG00000104883(PEX11G) "viable,visible" chaeta FBgn0004240 Dpt Diptericin http://flybase.net/reports/FBgn0004240.html protein_coding_gene "0019731=antibacterial humoral response, 0042742=defense response to bacterium, 0045089=positive regulation of innate immune response, 0009617=response to bacterium, 0045087=innate immune response, 0050829=defense response to Gram-negative bacterium" "diptericin, DPT, 143443_at, DiptericinA, dip, Dip, dipt, DiptA, Dipt, Dep, Diptericin precursor, diptericin A, Diptericin-A, Diptericin A, DptA, dpt, Dit, DIM 27, CG12763, DIPT" CG12763 16-Dec-15 2015_12 "viable,lethal,partially lethal - majority die,visible" "adult posterior midgut epithelium,mesothoracic tergum" FBgn0065468 l(2)SH1337 lethal (2) SH1337 http://flybase.net/reports/FBgn0065468.html gene l(2)SH2 1337 16-Dec-15 2015_12 "lethal,recessive" FBgn0004939 ABO-YS Abnormal Oocyte on YS http://flybase.net/reports/FBgn0004939.html region ABO 16-Dec-15 2015_12 FBgn0266865 CR45326 http://flybase.net/reports/FBgn0266865.html non_protein_coding_gene CR45326 16-Dec-15 2015_12 FBgn0262481 CG43071 http://flybase.net/reports/FBgn0262481.html protein_coding_gene lincRNA.347 CG43071 16-Dec-15 2015_12 FBgn0053236 Ste:CG33236 Ste:CG33236 http://flybase.net/reports/FBgn0053236.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33236" "IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG33236 16-Dec-15 2015_12 FBgn0028604 l(2)W3 lethal (2) W3 http://flybase.net/reports/FBgn0028604.html gene l(2R)W3 16-Dec-15 2015_12 "lethal,recessive" FBgn0008653 mn manikin http://flybase.net/reports/FBgn0008653.html gene 16-Dec-15 2015_12 "visible,male sterile,viable,male,poor" "adult abdomen,adult thorax" FBgn0060976 l(3)S028830 lethal (3) S028830 http://flybase.net/reports/FBgn0060976.html gene 0288/30 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0259392 C708 http://flybase.net/reports/FBgn0259392.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta,ectopic" FBgn0010009 Amr Amanatin resistant http://flybase.net/reports/FBgn0010009.html gene 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0266961 CR45412 http://flybase.net/reports/FBgn0266961.html non_protein_coding_gene CR45412 16-Dec-15 2015_12 FBgn0016667 Hrp62 Hrp62 http://flybase.net/reports/FBgn0016667.html gene 0003697=single-stranded DNA binding hrp62 16-Dec-15 2015_12 FBgn0035443 CG12010 http://flybase.net/reports/FBgn0035443.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" 0005783=endoplasmic reticulum "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG12010 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0027903 CG12018 http://flybase.net/reports/FBgn0027903.html protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0003677=DNA binding" "0006260=DNA replication, 0007052=mitotic spindle organization, 0006974=cellular response to DNA damage stimulus" "0043625=delta DNA polymerase complex, 0005875=microtubule associated complex" "DNApol- delta small subunit, 12018, BcDNA:HL03874, DNA polymerase delta small subunit" "IPR007185=DNA polymerase alpha/epsilon, subunit B, IPR024826=DNA polymerase delta/II small subunit family" CG12018 16-Dec-15 2015_12 ENSDARG00000041881(pold2) YJR006W(POL31) WBGene00008722(F12F6.7) ENSXETG00000019007(pold2) ENSMUSG00000020471(Pold2) ENSG00000106628(POLD2) "viable,visible" mesothoracic tergum FBgn0052220 Csas CMP-sialic acid synthase http://flybase.net/reports/FBgn0052220.html protein_coding_gene 0008781=N-acylneuraminate cytidylyltransferase activity "0007268=synaptic transmission, 0009408=response to heat, 0006055=CMP-N-acetylneuraminate biosynthetic process" 0005802=trans-Golgi network "cytidine monophosphate-sialic acid synthetase, CSAS, CG32220, DmCSAS" "IPR003329=Acylneuraminate cytidylyltransferase, IPR029044=Nucleotide-diphospho-sugar transferases" CG32220 16-Dec-15 2015_12 "viable,paralytic,neurophysiology defective,locomotor behavior defective,recessive" FBgn0265363 CR44304 http://flybase.net/reports/FBgn0265363.html non_protein_coding_gene CR44304 16-Dec-15 2015_12 FBgn0025155 ms(2)A12 ms(2)A12 http://flybase.net/reports/FBgn0025155.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0267041 CR45485 http://flybase.net/reports/FBgn0267041.html non_protein_coding_gene CR45485 16-Dec-15 2015_12 FBgn0058439 CG40439 http://flybase.net/reports/FBgn0058439.html FBan0040439 protein_coding_gene CG40439 16-Dec-15 2015_12 FBgn0261289 CheB98a Chemosensory protein A 98a http://flybase.net/reports/FBgn0261289.html "FBgn0067307, FBgn0040619" protein_coding_gene 0008289=lipid binding "0043695=detection of pheromone, 0007606=sensory perception of chemical stimulus" "0005615=extracellular space, 0005576=extracellular region" "CG14531, CheB98ap" "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG14531 16-Dec-15 2015_12 FBgn0033520 Prx2540-1 Peroxiredoxin 2540-1 http://flybase.net/reports/FBgn0033520.html FBgn0040497 protein_coding_gene "0016209=antioxidant activity, 0008379=thioredoxin peroxidase activity, 0004602=glutathione peroxidase activity, 0004601=peroxidase activity" "0042744=hydrogen peroxide catabolic process, 0055114=oxidation-reduction process" 0005829=cytosol "CG12405, 1-cys peroxiredoxin DPx- 2540-1, peroxiredoxin 2540, AOP2-related, Peroxiredoxin 2540, DPx2540, BEST:LD11278, DPx-2540-1, Prx2540" "IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336=Thioredoxin-like fold, IPR024706=Peroxiredoxin, AhpC-type, IPR019479=Peroxiredoxin, C-terminal" CG12405 16-Dec-15 2015_12 YBL064C(PRX1) WBGene00021401(prdx-6) FBgn0051315 CG31315 http://flybase.net/reports/FBgn0051315.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0027313 l(1)G0094 lethal (1) G0094 http://flybase.net/reports/FBgn0027313.html gene 16-Dec-15 2015_12 "partially lethal - majority live,female sterile,partially lethal - majority die,recessive" chaeta FBgn0043589 EK2-7 EK2-7 http://flybase.net/reports/FBgn0043589.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052811 CG32811 http://flybase.net/reports/FBgn0052811.html protein_coding_gene CG32811 16-Dec-15 2015_12 DRSC22649 K -0.813369712 0.375485171 0.026245544 -0.230067764 -0.501005956 1.50853484 FBgn0015524 otp orthopedia http://flybase.net/reports/FBgn0015524.html "FBgn0034559, FBgn0047081" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007417=central nervous system development, 0007379=segment specification, 0046331=lateral inhibition, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "BcDNA:RE58095, w26, bk24, Otp, W26, CG2965, Orthopedia, CG10036" "IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif, IPR017970=Homeobox, conserved site, IPR003654=OAR domain, IPR009057=Homeodomain-like" CG10036 16-Dec-15 2015_12 "ENSDARG00000058379(otpb),ENSDARG00000014201(otpa)" WBGene00006744(unc-4) "ENSMUSG00000021848(Otx2),ENSMUSG00000041578(Crx)" "ENSG00000165588(OTX2),ENSG00000115507(OTX1),ENSG00000105392(CRX)" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" DRSC04050 IK -0.48409083 -1.871483516 -0.366977855 0.666120827 1.289958843 2.069340552 FBgn0001392 l(1)2Cd lethal (1) 2Cd http://flybase.net/reports/FBgn0001392.html gene 16-Dec-15 2015_12 lethal FBgn0024975 CG2712 http://flybase.net/reports/FBgn0024975.html FBgn0020597 protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "EG:95B7.7, anon-3Be, Coding Region III, III" "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG2712 16-Dec-15 2015_12 "viable,fertile" FBgn0003377 Sgs7 Salivary gland secretion 7 http://flybase.net/reports/FBgn0003377.html FBgn0036166 protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion "0005576=extracellular region, 0005615=extracellular space" "group III, Gene III, sgs-7, Sgs-7, 68C GIII, sgs7, CG18087" CG18087 16-Dec-15 2015_12 larval stage | third instar embryonic/larval salivary gland

viable FBgn0086041 snoRNA:Me18S-A469 http://flybase.net/reports/FBgn0086041.html snoRNA_gene "Me18S-A469, Me18S-Am469, CR34670" CR34670 16-Dec-15 2015_12 FBgn0001411 l(1)3Da lethal (1) 3Da http://flybase.net/reports/FBgn0001411.html gene RA55 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" female reproductive system FBgn0017370 l(2)YOa lethal (2) YOa http://flybase.net/reports/FBgn0017370.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044112 E(rst)C317 E(rst)C317 http://flybase.net/reports/FBgn0044112.html gene 0001745=compound eye morphogenesis C317 16-Dec-15 2015_12 viable eye FBgn0038946 rdhB retinol dehydrogenase B http://flybase.net/reports/FBgn0038946.html protein_coding_gene 0004745=retinol dehydrogenase activity 0016063=rhodopsin biosynthetic process CG7077 "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR" CG7077 16-Dec-15 2015_12 "neurophysiology defective,viable" "rhabdomere,eye" FBgn0033810 CG4646 http://flybase.net/reports/FBgn0033810.html FBgn0062880 protein_coding_gene BcDNA:SD14289 "IPR008584=Protein of unknown function DUF866, eukaryotic" CG4646 16-Dec-15 2015_12 ENSDARG00000063341(si:ch211-284b7.3) YCR090C() WBGene00009776(F46B6.12) ENSXETG00000008071(C1orf123) ENSMUSG00000028608(0610037L13Rik) ENSG00000162384(C1orf123) viable FBgn0033672 rho-7 rhomboid-7 http://flybase.net/reports/FBgn0033672.html FBgn0044791 protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity, 0005515=protein binding" "0008053=mitochondrial fusion, 0016485=protein processing" "0016021=integral component of membrane, 0005739=mitochondrion" "anon-WO0138581.3, Rhomboid-7, PARL, CG8972, R7, Rho-7" "IPR002610=Peptidase S54, rhomboid, IPR022764=Peptidase S54, rhomboid domain" CG8972 16-Dec-15 2015_12 "ENSDARG00000039310(zgc:112986),ENSDARG00000020891(LOC792889)" YGR101W(PCP1) WBGene00004404(rom-5) ENSMUSG00000033918(Parl) ENSG00000175193(PARL) "visible,viable,male sterile,partially lethal - majority die,short lived,uncoordinated,neurophysiology defective" "eye,interommatidial bristle,testis,spermatozoon,mitochondrion,Nebenkern,seminal vesicle,indirect flight muscle,eye photoreceptor cell,rhabdomere" FBgn0003171 pink-wing pink wing http://flybase.net/reports/FBgn0003171.html gene pw 16-Dec-15 2015_12 "eye color defective,recessive,visible,viable,poor" "pigment cell,wing" FBgn0040350 CG3690 http://flybase.net/reports/FBgn0040350.html "FBgn0029550, FBgn0044618" protein_coding_gene "0055085=transmembrane transport, 0046331=lateral inhibition" 0016021=integral component of membrane "anon-WO0140519.250, EG:BACR7A4.13" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG3690 16-Dec-15 2015_12 "viable,visible" "chaeta,mesothoracic tergum" FBgn0037037 CG10588 http://flybase.net/reports/FBgn0037037.html protein_coding_gene "0046872=metal ion binding, 0004222=metalloendopeptidase activity" 0006508=proteolysis "IPR011249=Metalloenzyme, LuxS/M16 peptidase-like, IPR001431=Peptidase M16, zinc-binding site, IPR007863=Peptidase M16, C-terminal, IPR011237=Peptidase M16 domain, IPR011765=Peptidase M16, N-terminal" CG10588 16-Dec-15 2015_12 "ENSDARG00000019596(wu:fk24c07),ENSDARG00000062372(nrd1)" ENSXETG00000008054(NRD1) ENSMUSG00000053510(Nrd1) ENSG00000078618(NRD1) viable external sensory organ FBgn0265371 CR44312 http://flybase.net/reports/FBgn0265371.html non_protein_coding_gene CR44312 16-Dec-15 2015_12 FBgn0026400 Noa36 Noa36 http://flybase.net/reports/FBgn0026400.html protein_coding_gene "0008270=zinc ion binding, 0046872=metal ion binding" 0035167=larval lymph gland hemopoiesis "0005730=nucleolus, 0000775=chromosome, centromeric region, 0030496=midbody" "NOA36, CG10009, NOA 36, noa36" IPR010531=Zinc finger protein NOA36 CG10009 16-Dec-15 2015_12 ENSDARG00000020494(znf330) ENSXETG00000014970(znf330) ENSMUSG00000031711(Zfp330) ENSG00000109445(ZNF330) "viable,fertile,partially lethal - majority die,lethal,visible" mesothoracic tergum FBgn0263860 P171 P171 http://flybase.net/reports/FBgn0263860.html gene "0008306=associative learning, 0007613=memory" 16-Dec-15 2015_12 "learning defective,recessive,memory defective" FBgn0030204 Or9a Odorant receptor 9a http://flybase.net/reports/FBgn0030204.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "9a, 9E.1, CG15302, OR9a, DOR95, DmOr9a, or9a" "IPR004117=Olfactory receptor, Drosophila" CG15302 16-Dec-15 2015_12 viable FBgn0019669 ms(2)50Ca ms(2)50Ca http://flybase.net/reports/FBgn0019669.html gene 16-Dec-15 2015_12 FBgn0266391 CR45031 http://flybase.net/reports/FBgn0266391.html non_protein_coding_gene CR45031 16-Dec-15 2015_12 FBgn0040968 CG14933 http://flybase.net/reports/FBgn0040968.html protein_coding_gene IPR002350=Kazal domain CG14933 16-Dec-15 2015_12 viable FBgn0034717 CG5819 http://flybase.net/reports/FBgn0034717.html protein_coding_gene "CT18212, tartan/capricious-like, 5819" "IPR001611=Leucine-rich repeat, IPR000483=Cysteine-rich flanking region, C-terminal" CG5819 16-Dec-15 2015_12 viable FBgn0035040 CG4741 http://flybase.net/reports/FBgn0035040.html protein_coding_gene CG4741 16-Dec-15 2015_12 DRSC25673 K -0.027019529 -0.015658976 -0.002210613 -0.02466791 -0.047734911 1.596890621 FBgn0264298 CG43776 http://flybase.net/reports/FBgn0264298.html FBgn0034979 protein_coding_gene 0005576=extracellular region "CG13569, CG13569-2" "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG43776 16-Dec-15 2015_12 viable FBgn0259560 GG01554 http://flybase.net/reports/FBgn0259560.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing cell,wing vein,leg,unguis,antennal segment,arista" FBgn0262538 CG43092 http://flybase.net/reports/FBgn0262538.html protein_coding_gene CG43092 16-Dec-15 2015_12 FBgn0001348 l(1)1Ec lethal (1) 1Ec http://flybase.net/reports/FBgn0001348.html gene "EA1, 28/6A" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0084144 l(2)neo1 lethal (2) neo1 http://flybase.net/reports/FBgn0084144.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041625 Or65a Odorant receptor 65a http://flybase.net/reports/FBgn0041625.html FBgn0052401 protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "LU27.2, odorant receptor 65a, DOR66, 65a, CG32401" "IPR004117=Olfactory receptor, Drosophila" CG32401 16-Dec-15 2015_12 viable DRSC08808 K 1.169748629 0.471930075 0.064531934 -0.145232606 0.761275982 -1.715694135 FBgn0266031 CR44796 http://flybase.net/reports/FBgn0266031.html non_protein_coding_gene CR44796 16-Dec-15 2015_12 FBgn0043070 MESK2 Misexpression suppressor of KSR 2 http://flybase.net/reports/FBgn0043070.html "FBgn0010491, FBgn0034632, FBgn0034633, FBgn0046775, FBgn0047042, FBgn0064967" protein_coding_gene 0046579=positive regulation of Ras protein signal transduction "Mesk2, CG15669, l(2)01467, BcDNA:LD27504, BcDNA:RH10174, mesk2, CG15668, BcDNA:GH12032, unnamed" "IPR029058=Alpha/Beta hydrolase fold, IPR004142=NDRG" CG15669 16-Dec-15 2015_12 "ENSDARG00000010420(ndrg1l),ENSDARG00000032849(ndrg1),ENSDARG00000010052(ndrg3b),ENSDARG00000013087(ndrg3a),ENSDARG00000062236(ndrg4),ENSDARG00000011170(zgc:101847)" WBGene00013020(Y48G10A.3) "ENSXETG00000009993(ndrg3),ENSXETG00000010988(ndrg1),ENSXETG00000013742(BC075414.1),ENSXETG00000016160(ndrg2)" "ENSMUSG00000027634(Ndrg3),ENSMUSG00000005125(Ndrg1),ENSMUSG00000036564(Ndrg4),ENSMUSG00000004558(Ndrg2)" "ENSG00000101079(NDRG3),ENSG00000104419(NDRG1),ENSG00000103034(NDRG4),ENSG00000165795(NDRG2)" "viable,fertile,lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing vein" FBgn0043902 fad fat-head http://flybase.net/reports/FBgn0043902.html gene "0009950=dorsal/ventral axis specification, 0009798=axis specification" 16-Dec-15 2015_12 FBgn0262127 kibra kibra ortholog http://flybase.net/reports/FBgn0262127.html "FBgn0053967, FBgn0038254, FBgn0038255, FBtr0082970, FBpp0082429, FBtr0083022, FBpp0082481, FBgn0010779, FBgn0011381, FBgn0011475" protein_coding_gene 0005515=protein binding "0007298=border follicle cell migration, 0035330=regulation of hippo signaling, 0060253=negative regulation of glial cell proliferation, 0001745=compound eye morphogenesis" "0045177=apical part of cell, 0005737=cytoplasm" "kbr, lethal (3) neo42, l(3)j5C3, CG33967, l(3)neo42, Kibra, l(3)02404, CG12600, RE26350, kib, kibra, Kib, CG7552, ORE-2" "IPR000008=C2 domain, IPR001202=WW domain" CG33967 16-Dec-15 2015_12 ENSDARG00000061654(zgc:158241) "ENSXETG00000025753(Q6DJR2_XENTR),ENSXETG00000015746(WWC3)" "ENSMUSG00000018849(Wwc1),ENSMUSG00000031563(Wwc2)" "ENSG00000113645(WWC1),ENSG00000151718(WWC2),ENSG00000047644(WWC3)" FBgn0065957 l(2)SH0053 lethal (2) SH0053 http://flybase.net/reports/FBgn0065957.html gene l(2)SH2 0053 16-Dec-15 2015_12 "lethal,recessive" FBgn0263955 BG01042 http://flybase.net/reports/FBgn0263955.html gene 16-Dec-15 2015_12 "long lived,male limited,short lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0022296 l(1)M52.3 lethal (1) M52.3 http://flybase.net/reports/FBgn0022296.html gene M52.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0024833 AP-1ë_ "Adaptor Protein complex 1, ë_ subunit" http://flybase.net/reports/FBgn0024833.html protein_coding_gene "0008565=protein transporter activity, 0030276=clathrin binding" "2001136=negative regulation of endocytic recycling, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0033363=secretory granule organization, 0045746=negative regulation of Notch signaling pathway, 0007269=neurotransmitter secretion, 0016183=synaptic vesicle coating, 0006901=vesicle coating, 0048749=compound eye development, 0046907=intracellular transport" "0030136=clathrin-coated vesicle, 0035976=AP1 complex, 0030135=coated vesicle, 0008021=synaptic vesicle, 0030121=AP-1 adaptor complex" "APmu1, apm1, mu1, cg9388, AP47, Dmu1, AP-1mu1, AP-47, ap-47, AP1mu1, CG9388" "IPR001392=Clathrin adaptor, mu subunit, IPR011012=Longin-like domain, IPR022775=AP complex, mu/sigma subunit, IPR018240=Clathrin adaptor, mu subunit, conserved site, IPR028565=Mu homology domain" CG9388 16-Dec-15 2015_12 ENSDARG00000039512(LOC570897) YPL259C(APM1) WBGene00006829(unc-101) ENSXETG00000013600(ap1m1) ENSMUSG00000003033(Ap1m1) ENSG00000072958(AP1M1) embryonic stage -- adult stage "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,body color defective" "eye,somatic clone,tormogen cell,supernumerary,embryonic/larval salivary gland,secretory granule,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,ommatidium,mesothoracic tergum" FBgn0031375 erm earmuff http://flybase.net/reports/FBgn0031375.html FBgn0051670 protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0019827=stem cell maintenance, 0007406=negative regulation of neuroblast proliferation, 0050767=regulation of neurogenesis, 0045892=negative regulation of transcription, DNA-templated" "dfezl, dFezf, CG7312, earmuff, CG31670" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG31670 16-Dec-15 2015_12 "ENSDARG00000010270(fezf1),ENSDARG00000070677(fezf2),ENSDARG00000070678" "neuroanatomy defective,somatic clone,lethal,viable,fertile" "type II neuroblast | third instar larval stage,type II neuroblast,somatic clone,supernumerary,supernumerary | third instar larval stage,embryonic/larval neuroblast,ectopic" FBgn0003180 pyp polyphene http://flybase.net/reports/FBgn0003180.html gene 16-Dec-15 2015_12 "female sterile,partially lethal - majority live" "eye,wing,3rd posterior cell,trident,male" FBgn0086290 GS5036 http://flybase.net/reports/FBgn0086290.html gene 5036 16-Dec-15 2015_12 FBgn0060762 l(3)S063218 lethal (3) S063218 http://flybase.net/reports/FBgn0060762.html gene 0632/18 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0259351 C79 http://flybase.net/reports/FBgn0259351.html gene 16-Dec-15 2015_12 "visible,lethal" wing hair FBgn0028098 l(3)S073615 lethal (3) S073615 http://flybase.net/reports/FBgn0028098.html gene 0736/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067062 O4 O4 http://flybase.net/reports/FBgn0067062.html gene 16-Dec-15 2015_12 "lethal,viable" FBgn0044442 HMS-Beagle\gag gag http://flybase.net/reports/FBgn0044442.html transposable_element_gene 16-Dec-15 2015_12 FBgn0051719 RluA-1 RluA-1 http://flybase.net/reports/FBgn0051719.html "FBgn0032254, FBgn0032255" protein_coding_gene "0003723=RNA binding, 0008835=diaminohydroxyphosphoribosylaminopyrimidine deaminase activity, 0009982=pseudouridine synthase activity" "0001522=pseudouridine synthesis, 0009231=riboflavin biosynthetic process" "multiple, CG7475, CG13143, CG31719" "IPR006225=Pseudouridine synthase, RluC/RluD, IPR006224=Pseudouridine synthase, RluC/RluD, conserved site, IPR020103=Pseudouridine synthase, catalytic domain, IPR006145=Pseudouridine synthase, RsuA/RluB/C/D/E/F" CG31719 16-Dec-15 2015_12 ENSDARG00000060992(LOC565088) "YOL066C(RIB2),YDL036C(PUS9)" WBGene00019498(K07E8.7) ENSXETG00000015973(RPUSD2) ENSMUSG00000027324(Rpusd2) ENSG00000166133(RPUSD2) "viable,fertile" FBgn0070029 BG00158 BG00158 http://flybase.net/reports/FBgn0070029.html gene 16-Dec-15 2015_12 stress response defective FBgn0084500 lep leprechaun http://flybase.net/reports/FBgn0084500.html gene E-3c 16-Dec-15 2015_12 "lethal,recessive" FBgn0260656 CG42539 http://flybase.net/reports/FBgn0260656.html protein_coding_gene HCD15482 16-Dec-15 2015_12 FBgn0060894 l(3)S044437 lethal (3) S044437 http://flybase.net/reports/FBgn0060894.html gene 0444/37 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065887 l(2)SH0226 lethal (2) SH0226 http://flybase.net/reports/FBgn0065887.html gene l(2)SH2 0226 16-Dec-15 2015_12 "lethal,recessive" FBgn0010034 E(var)7 Enhancer of variegation http://flybase.net/reports/FBgn0010034.html gene Evar7 16-Dec-15 2015_12 enhancer of variegation FBgn0053746 snmRNA:430:CR33746 snmRNA:430:CR33746 http://flybase.net/reports/FBgn0053746.html non_protein_coding_gene CR33746 CR33746 16-Dec-15 2015_12 FBgn0027176 l(2)60Ah lethal (2) 60Ah http://flybase.net/reports/FBgn0027176.html gene "ET/141, unnamed, Unassigned in interval 5" 16-Dec-15 2015_12 "lethal,recessive" FBgn0065847 l(2)SH0315 lethal (2) SH0315 http://flybase.net/reports/FBgn0065847.html gene l(2)SH2 0315 16-Dec-15 2015_12 "lethal,recessive" FBgn0085455 CG34426 http://flybase.net/reports/FBgn0085455.html "FBan0013307, FBgn0035930" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG13307 IPR002557=Chitin binding domain CG34426 16-Dec-15 2015_12 FBgn0043782 Burdock\gag gag http://flybase.net/reports/FBgn0043782.html transposable_element_gene 16-Dec-15 2015_12 FBgn0085813 18SrRNA-ë¬:CR41602 18S ribosomal RNA pseudogene:CR41602 http://flybase.net/reports/FBgn0085813.html FBan0041602 pseudogene_attribute CR41602 CR41602 16-Dec-15 2015_12 FBgn0065404 l(2)SH1594 lethal (2) SH1594 http://flybase.net/reports/FBgn0065404.html gene l(2)SH2 1594 16-Dec-15 2015_12 "lethal,recessive" FBgn0003380 Sh Shaker http://flybase.net/reports/FBgn0003380.html "FBgn0030885, FBgn0030888, FBgn0064981" protein_coding_gene "0022843=voltage-gated cation channel activity, 0005249=voltage-gated potassium channel activity, 0005251=delayed rectifier potassium channel activity" "0008345=larval locomotory behavior, 0051260=protein homooligomerization, 0048047=mating behavior, sex discrimination, 0007611=learning or memory, 0007637=proboscis extension reflex, 0060025=regulation of synaptic activity, 0006813=potassium ion transport, 0055085=transmembrane transport, 0050909=sensory perception of taste, 0048675=axon extension, 0030431=sleep, 0001508=action potential, 0007619=courtship behavior, 0048150=behavioral response to ether, 0007629=flight behavior, 0045187=regulation of circadian sleep/wake cycle, sleep, 0009584=detection of visible light" "0016021=integral component of membrane, 0008076=voltage-gated potassium channel complex" "Shaker-downheld, CG17860, sh, BcDNA:GH03046, CG12348, Sha, sha, Shaker, F-c transcription unit, F-c, CG7640, Shw, EKO, minisleep, SH, shaker, V-I, Eko, Kv1" "IPR003968=Potassium channel, voltage dependent, Kv, IPR028325=Voltage-gated potassium channel, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR011333=POZ domain, IPR004048=Potassium channel, voltage dependent, Kv1.1, IPR005821=Ion transport domain, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR000210=BTB/POZ domain, IPR003091=Potassium channel, IPR003972=Potassium channel, voltage dependent, Kv1" CG12348 16-Dec-15 2015_12 "ENSDARG00000063282(LOC100330283),ENSDARG00000052944,ENSDARG00000062942(LOC795942),ENSDARG00000002241(zgc:174907),ENSDARG00000017108(LOC571208),ENSDARG00000068669,ENSDARG00000061753(LOC100004160)" WBGene00014261(shk-1) "ENSXETG00000017753(kcna2),ENSXETG00000017758(KCNA2),ENSXETG00000008490(KCNA1),ENSXETG00000008488(KCNA6),ENSXETG00000018247(KCNA4),ENSXETG00000008493(Q5HZU1_XENTR)" "ENSMUSG00000040724(Kcna2),ENSMUSG00000047976(Kcna1),ENSMUSG00000047959(Kcna3),ENSMUSG00000042604(Kcna4)" "ENSG00000177301(KCNA2),ENSG00000111262(KCNA1),ENSG00000177272(KCNA3),ENSG00000182255(KCNA4)" "courtship behavior defective,viable,fertile,behavior defective,dominant,uncoordinated,short lived,neurophysiology defective,locomotor behavior defective,chemical sensitive,hyperactive,lethal,recessive,taste perception defective,smell perception defective,visible,chemical resistant,male,chemosensitive behavior defective,RU486 conditional,visual behavior defective,cold sensitive,body color defective,circadian behavior defective,sleep defective,flight defective,locomotor rhythm defective" "axon & motor neuron | conditional ts,giant fiber neuron,neuromuscular junction,synapse,end plate,photoreceptor cell,muscle fiber,wing,adult thorax,leg,embryonic/larval neuromuscular junction,photoreceptor,presumptive embryonic/larval muscle system,embryonic/larval neuron,motor neuron,eye,adult cuticle,larval head,cold sensitive,abdomen | adult stage A1,RU486 conditional" FBgn0001779 l(1)M64 lethal (1) M64 http://flybase.net/reports/FBgn0001779.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002290 l(3)80Fa lethal (3) 80Fa http://flybase.net/reports/FBgn0002290.html gene "l(3)Lh8, 80Fa, l8, lethal 8" 16-Dec-15 2015_12 lethal FBgn0038105 yellow-f2 yellow-f2 http://flybase.net/reports/FBgn0038105.html protein_coding_gene 0004167=dopachrome isomerase activity "0006583=melanin biosynthetic process from tyrosine, 0042435=indole-containing compound biosynthetic process, 0048067=cuticle pigmentation, 0042438=melanin biosynthetic process, 0048066=developmental pigmentation" 0005576=extracellular region "CG8063, yel-f2" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG8063 16-Dec-15 2015_12 viable FBgn0034628 Acox57D-p acyl-Coenzyme A oxidase at 57D proximal http://flybase.net/reports/FBgn0034628.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016401=palmitoyl-CoA oxidase activity, 0003995=acyl-CoA dehydrogenase activity, 0003997=acyl-CoA oxidase activity" 0006635=fatty acid beta-oxidation 0005777=peroxisome "D-acox, Acox57Dp, acyl co-enzyme A oxidase, CG9707, acox" "IPR012258=Acyl-CoA oxidase, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320=Acyl-coenzyme A oxidase, N-terminal, IPR002655=Acyl-CoA oxidase, C-terminal, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain" CG9707 16-Dec-15 2015_12 ENSDARG00000014727(acox1) "WBGene00010336(F59F4.1),WBGene00009104(F25C8.1),WBGene00008564(F08A8.1),WBGene00008567(F08A8.4),WBGene00008566(F08A8.3),WBGene00008565(F08A8.2),WBGene00008167(C48B4.1)" "ENSXETG00000012601(acox1),ENSXETG00000023676(acox2)" ENSMUSG00000020777(Acox1) ENSG00000161533(ACOX1) FBgn0014868 Ost48 Oligosaccharyltransferase 48kD subunit http://flybase.net/reports/FBgn0014868.html FBgn0026008 protein_coding_gene 0004579=dolichyl-diphosphooligosaccharide-protein glycotransferase activity "0007030=Golgi organization, 0034389=lipid particle organization, 0018279=protein N-linked glycosylation via asparagine, 0022008=neurogenesis, 0006487=protein N-linked glycosylation" "0012505=endomembrane system, 0005811=lipid particle, 0005789=endoplasmic reticulum membrane" "OST, OST48/WBP1, anon-EST:Liang-1.11, OST48, clone 1.11, Ots48, DrOST, DmOST50, CG9022, ost48, oligosaccaryltransferase 48kDa subunit" IPR005013=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit CG9022 16-Dec-15 2015_12 ENSDARG00000037318(ddost) YEL002C(WBP1) WBGene00011638(ostb-1) ENSXETG00000019826(DDOST) ENSMUSG00000028757(Ddost) ENSG00000117242 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001691 l(1)ESHS12 lethal (1) ESHS12 http://flybase.net/reports/FBgn0001691.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022945 CFDD Common regulatory Factor for DNA replication and DREF genes http://flybase.net/reports/FBgn0022945.html gene 0003677=DNA binding 0005634=nucleus 16-Dec-15 2015_12 FBgn0014092 CG4278 http://flybase.net/reports/FBgn0014092.html protein_coding_gene "un5, unnamed, anon-35F/36A, BG:DS02740.16" IPR002678=GTP cyclohydrolase 1 type 2/Nif3 CG4278 16-Dec-15 2015_12 YGL221C(NIF3) ENSXETG00000018172(nif3l1) embryonic stage | early viable FBgn0028496 CG30116 http://flybase.net/reports/FBgn0028496.html "FBgn0034353, FBgn0050116" protein_coding_gene 0016505=peptidase activator activity involved in apoptotic process "CG17671, BcDNA:GH04922, CG5512" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020472=G-protein beta WD-40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG30116 16-Dec-15 2015_12 WBGene00004265(qui-1) "viable,fertile" FBgn0021819 l(2)k16215 lethal (2) k16215 http://flybase.net/reports/FBgn0021819.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0051418 CG31418 http://flybase.net/reports/FBgn0051418.html FBgn0038496 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG5329 CG31418 16-Dec-15 2015_12 viable FBgn0264714 CG43982 http://flybase.net/reports/FBgn0264714.html protein_coding_gene CG43982 16-Dec-15 2015_12 FBgn0015780 Onf-AATAA Ovarian nuclear factor-AATAA http://flybase.net/reports/FBgn0015780.html gene ONF-AATAA 16-Dec-15 2015_12 FBgn0265719 CR44526 http://flybase.net/reports/FBgn0265719.html non_protein_coding_gene "incRNA.476, lincRNA.476" CR44526 16-Dec-15 2015_12 FBgn0050145 Obp57e Odorant-binding protein 57e http://flybase.net/reports/FBgn0050145.html FBgn0034516 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG30145, Obp57d, CG13429, DmelObp57e, Dmel\Obp57e, 57e, OBP57e" IPR006170=Pheromone/general odorant binding protein CG30145 16-Dec-15 2015_12 viable FBgn0040103 lectin-24Da lectin-24Da http://flybase.net/reports/FBgn0040103.html gene 0005534=galactose binding "AC004279a, AC 004279A" 16-Dec-15 2015_12 FBgn0000373 cripB crippled B http://flybase.net/reports/FBgn0000373.html gene 16-Dec-15 2015_12 "hypoactive,visible,uncoordinated" eye FBgn0039850 CG11333 http://flybase.net/reports/FBgn0039850.html FBgn0063361 protein_coding_gene 0003824=catalytic activity 0008152=metabolic process BcDNA:AT02774 IPR000868=Isochorismatase-like CG11333 16-Dec-15 2015_12 "ENSDARG00000060069(isoc1),ENSDARG00000013371(isoc2)" WBGene00009436(F35G2.2) ENSXETG00000008281(ISOC1) ENSMUSG00000024601(Isoc1) ENSG00000066583(ISOC1) viable FBgn0002655 mat(2)cell-D maternal effect cellularisation defect D http://flybase.net/reports/FBgn0002655.html gene 0007349=cellularization mat(2)cellPQ49 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0266399 CR45039 http://flybase.net/reports/FBgn0266399.html non_protein_coding_gene CR45039 16-Dec-15 2015_12 FBgn0034187 CG6967 http://flybase.net/reports/FBgn0034187.html protein_coding_gene "0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" CT21565 IPR027417=P-loop containing nucleoside triphosphate hydrolase CG6967 16-Dec-15 2015_12 YKL017C(HCS1) WBGene00016566(eri-7) "viable,fertile" FBgn0063647 CE2-2 "Calcineurin enhancer, chromosome 2, group 2" http://flybase.net/reports/FBgn0063647.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022366 Pt-7 Larval protein-7 http://flybase.net/reports/FBgn0022366.html gene 16-Dec-15 2015_12 FBgn0265194 Trpm "Transient receptor potential cation channel, subfamily M ortholog" http://flybase.net/reports/FBgn0265194.html "FBgn0083959, FBan0030079, FBgn0034006, FBgn0050078, FBgn0050079, FBgn0064975, FBgn0265175, FBgn0085216" protein_coding_gene "0097682=intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity, 0046873=metal ion transmembrane transporter activity, 0005261=cation channel activity" "0043052=thermotaxis, 0016049=cell growth, 0055069=zinc ion homeostasis, 0070838=divalent metal ion transport, 0010960=magnesium ion homeostasis, 0055085=transmembrane transport, 0007005=mitochondrion organization" 0034703=cation channel complex "CG30079, dTRPM, CG44240, TrpM, DmTRPM, CG16805, BcDNA:GH04950, transient receptor potential channel M, mdcds_11815, TRPM, CG34123, CG30078, CG34187, trpm" IPR005821=Ion transport domain CG44240 16-Dec-15 2015_12 "ENSDARG00000039181(LOC565807),ENSDARG00000011259" WBGene00001651(gon-2) "ENSXETG00000016479(TRPM1),ENSXETG00000001048(TRPM6)" "ENSMUSG00000052387(Trpm3),ENSMUSG00000030523(Trpm1),ENSMUSG00000027365(Trpm7),ENSMUSG00000024727(Trpm6)" "ENSG00000083067(TRPM3),ENSG00000134160(TRPM1),ENSG00000092439(TRPM7),ENSG00000119121(TRPM6)" FBgn0085235 CG34206 http://flybase.net/reports/FBgn0085235.html protein_coding_gene CG34206 16-Dec-15 2015_12 FBgn0028387 chm chameau http://flybase.net/reports/FBgn0028387.html FBgn0031911 protein_coding_gene "0004402=histone acetyltransferase activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003713=transcription coactivator activity, 0008134=transcription factor binding, 0008270=zinc ion binding, 0010485=H4 histone acetyltransferase activity" "0009996=negative regulation of cell fate specification, 0016360=sensory organ precursor cell fate determination, 0048813=dendrite morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048666=neuron development, 0046529=imaginal disc fusion, thorax closure, 0048190=wing disc dorsal/ventral pattern formation, 0022416=chaeta development, 0016458=gene silencing, 0016573=histone acetylation, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "HAT, dmHAG404, CG5229, HBO1, Chm, HAT1" "IPR002717=Histone acetyltransferase domain, MYST-type, IPR016181=Acyl-CoA N-acyltransferase, IPR002515=Zinc finger, C2HC-type" CG5229 16-Dec-15 2015_12 "ENSDARG00000031770(myst2),ENSDARG00000070373,ENSDARG00000070377" ENSXETG00000021908(myst2) ENSMUSG00000038909(Myst2) ENSG00000136504(KAT7) "suppressor of variegation,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wild-type,viable" adult thorax DRSC24941 K -0.371367026 -0.347656926 0.370704248 0.530648663 -1.502221657 0.153279396 FBgn0039840 CG11340 http://flybase.net/reports/FBgn0039840.html protein_coding_gene 0016934=extracellular-glycine-gated chloride channel activity 0006811=ion transport 0016935=glycine-gated chloride channel complex "glycine-gated chloride channel-like, CT5896, lincRNA.914" "IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha" CG11340 16-Dec-15 2015_12 "viable,fertile" DRSC14306 EK 1.016128472 0.681938305 1.863558529 1.254861527 0.556120495 1.730679265 FBgn0036220 CG5897 http://flybase.net/reports/FBgn0036220.html protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG5897 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0051976 CG31976 http://flybase.net/reports/FBgn0051976.html FBgn0031222 protein_coding_gene CG11623 "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG31976 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0005124 l(1)J1743 lethal (1) J1743 http://flybase.net/reports/FBgn0005124.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0069132 mei(2)yh149 mei(2)yh149 http://flybase.net/reports/FBgn0069132.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,female fertile" FBgn0003670 tbl tasteblind http://flybase.net/reports/FBgn0003670.html gene 16-Dec-15 2015_12 chemosensitive behavior defective FBgn0259627 B2033 http://flybase.net/reports/FBgn0259627.html gene 16-Dec-15 2015_12 visible wing FBgn0036196 CG11658 http://flybase.net/reports/FBgn0036196.html FBgn0062027 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "anon-WO0118547.413, FBXO12" IPR001810=F-box domain CG11658 16-Dec-15 2015_12 "ENSDARG00000040277(fbxo32),ENSDARG00000004116(fbxo25)" WBGene00008439(mfb-1) "ENSXETG00000023228(FBXO32),ENSXETG00000016768(Q569D4_XENTR)" "ENSMUSG00000022358(Fbxo32),ENSMUSG00000038365(Fbxo25)" "ENSG00000156804(FBXO32),ENSG00000147364(FBXO25)" "viable,fertile" FBgn0024368 CG18091 http://flybase.net/reports/FBgn0024368.html FBgn0029572 protein_coding_gene EG:190E7.1 16-Dec-15 2015_12 viable FBgn0005213 l(3)ET4 lethal Elaine Tasaka 4 http://flybase.net/reports/FBgn0005213.html gene 16-Dec-15 2015_12 "lethal,cold sensitive,heat sensitive" FBgn0050379 CG30379 http://flybase.net/reports/FBgn0050379.html protein_coding_gene 0004972=N-methyl-D-aspartate selective glutamate receptor activity 0017146=N-methyl-D-aspartate selective glutamate receptor complex IPR006214=Bax inhibitor 1-related CG30379 16-Dec-15 2015_12 YNL305C() viable FBgn0041760 efe efendi http://flybase.net/reports/FBgn0041760.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,recessive,lethal - all die before end of pupal stage,partially,some die during pupal stage,chemical resistant,dominant" "polytene chromosome,melanotic mass,embryonic/larval brain,salivary gland" FBgn0016799 l(1)44 lethal (1) 44 http://flybase.net/reports/FBgn0016799.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0024680 l(1)LefEM26 lethal (1) LefEM26 http://flybase.net/reports/FBgn0024680.html gene EM26 16-Dec-15 2015_12 FBgn0043457 CG5180 http://flybase.net/reports/FBgn0043457.html "FBgn0038802, FBgn0063600" protein_coding_gene "LD05530, BEST:LD05530" IPR006578=MADF domain CG5180 16-Dec-15 2015_12 "visible,viable" "dorsocentral bristle,scutellar bristle,trichogen cell,ectopic,thecogen cell" FBgn0062573 Mod(var)E1275 Mod(var)E1275 http://flybase.net/reports/FBgn0062573.html gene 0006342=chromatin silencing E1275 16-Dec-15 2015_12 "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0032117 FucTB FucTB http://flybase.net/reports/FBgn0032117.html protein_coding_gene "0046920=alpha-(1->3)-fucosyltransferase activity, 0008417=fucosyltransferase activity" 0006486=protein glycosylation "0000139=Golgi membrane, 0005886=plasma membrane" "CT14430, alpha1,3-fucosyltransferase, CG4435" "IPR001503=Glycosyl transferase family 10, IPR017176=Alpha-(1, 3)-fucosyltransferase, metazoan" CG4435 16-Dec-15 2015_12 "ENSDARG00000029601(fut10),ENSDARG00000057727(zgc:153537)" "ENSXETG00000017502(AJ784815.1),ENSXETG00000015541(Q6A1G2_XENTR)" "ENSMUSG00000046152(Fut10),ENSMUSG00000039357(Fut11)" "ENSG00000172728(FUT10),ENSG00000196968(FUT11)" viable FBgn0025150 ms(2)A6 ms(2)A6 http://flybase.net/reports/FBgn0025150.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0264509 CR43908 http://flybase.net/reports/FBgn0264509.html non_protein_coding_gene CR43908 16-Dec-15 2015_12 FBgn0266315 CR44980 http://flybase.net/reports/FBgn0266315.html non_protein_coding_gene CR44980 16-Dec-15 2015_12 FBgn0085607 CG41311 http://flybase.net/reports/FBgn0085607.html FBan0041311 protein_coding_gene 16-Dec-15 2015_12 FBgn0261085 Syt12 Synaptotagmin 12 http://flybase.net/reports/FBgn0261085.html "FBgn0084992, FBgn0030476" protein_coding_gene 0005544=calcium-dependent phospholipid binding "0007269=neurotransmitter secretion, 0060291=long-term synaptic potentiation, 0046928=regulation of neurotransmitter secretion" "0016020=membrane, 0008021=synaptic vesicle, 0016021=integral component of membrane" "syt12, dsyt12, CG10617, Syt 12, unnamed, synaptotagmin 12" "IPR000008=C2 domain, IPR030537=Synaptotagmin-12" CG10617 16-Dec-15 2015_12 "ENSG00000213023(SYT3),ENSG00000170743(SYT9),ENSG00000134207(SYT6),ENSG00000110975(SYT10)" FBgn0044029 NOF\ORF ORF http://flybase.net/reports/FBgn0044029.html transposable_element_gene 16-Dec-15 2015_12 FBgn0051419 CG31419 http://flybase.net/reports/FBgn0051419.html FBgn0038496 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG5329 CG31419 16-Dec-15 2015_12 FBgn0034649 CG9865 http://flybase.net/reports/FBgn0034649.html protein_coding_gene "0016758=transferase activity, transferring hexosyl groups" 0006506=GPI anchor biosynthetic process 0016021=integral component of membrane Dromel_CG9865_FBtr0071680_cx9c_morf "IPR007704=Mannosyltransferase, DXD" CG9865 16-Dec-15 2015_12 ENSDARG00000024277 YJR013W(GPI14) WBGene00007189(B0491.1) ENSXETG00000006188(TGas014d02.1) ENSMUSG00000050229(Pigm) ENSG00000143315(PIGM) FBgn0015725 Eig82F Ecdysone induced gene at 82F http://flybase.net/reports/FBgn0015725.html gene 16-Dec-15 2015_12 FBgn0085499 CG40600 http://flybase.net/reports/FBgn0085499.html FBan0040600 protein_coding_gene 16-Dec-15 2015_12 FBgn0040763 CG18336 http://flybase.net/reports/FBgn0040763.html FBgn0033611 protein_coding_gene CG13212 IPR018902=Uncharacterised protein family UPF0573/UPF0605 CG18336 16-Dec-15 2015_12 viable FBgn0038306 Art3 Arginine methyltransferase 3 http://flybase.net/reports/FBgn0038306.html protein_coding_gene 0016274=protein-arginine N-methyltransferase activity 0018216=peptidyl-arginine methylation "CG6563, DART3" "IPR025799=Protein arginine N-methyltransferase, IPR025714=Methyltransferase domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG6563 16-Dec-15 2015_12 ENSDARG00000019791(prmt3) ENSXETG00000014186(PRMT3) ENSMUSG00000030505(Prmt3) ENSG00000185238(PRMT3) "viable,fertile" FBgn0019852 anon-XII anon-XII http://flybase.net/reports/FBgn0019852.html gene XII 16-Dec-15 2015_12 FBgn0024941 RSG7 Regulator of G-protein signalling 7 http://flybase.net/reports/FBgn0024941.html "FBtr0074350, FBpp0074124" protein_coding_gene "0005096=GTPase activator activity, 0004871=signal transducer activity" "0008277=regulation of G-protein coupled receptor protein signaling pathway, 0038032=termination of G-protein coupled receptor signaling pathway, 0035556=intracellular signal transduction" "0005737=cytoplasm, 0005834=heterotrimeric G-protein complex, 0005886=plasma membrane" "dRGS7, regulator of g protein signaling 7, CG9108, RGS7" "IPR024066=RGS, subdomain 1, IPR000591=DEP domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR015898=G-protein gamma-like domain, IPR016137=RGS domain" CG9108 16-Dec-15 2015_12 "ENSDARG00000016584(rgs7),ENSDARG00000015627(rgs6)" WBGene00001179(egl-10) ENSXETG00000021836(RGS6) "ENSMUSG00000026527(Rgs7),ENSMUSG00000021219(Rgs6)" "ENSG00000182901(RGS7),ENSG00000182732(RGS6)" "partially lethal - majority die,some die during pupal stage" DRSC20274 EK 0.088714279 0.479881958 -0.166699895 1.755589105 -1.513719552 -0.695144892 FBgn0261686 CG42733 http://flybase.net/reports/FBgn0261686.html FBgn0033513 protein_coding_gene "Tes85-2, CG12901" CG42733 16-Dec-15 2015_12 viable FBgn0052529 Hers Histone gene-specific Epigenetic Repressor in late S phase http://flybase.net/reports/FBgn0052529.html "FBgn0031075, FBgn0031076" protein_coding_gene "0000976=transcription regulatory region sequence-specific DNA binding, 0003682=chromatin binding" "0006342=chromatin silencing, 0007476=imaginal disc-derived wing morphogenesis, 0006338=chromatin remodeling" "CG32529, CG11936, HERS, CG15619" IPR001025=Bromo adjacent homology (BAH) domain CG32529 16-Dec-15 2015_12 "suppressor of variegation,viable,fertile" eye DRSC19429 K 1.048545568 1.163515932 -0.436466355 0.4944286 1.852608506 1.954492388 FBgn0032749 Phlpp PH domain leucine-rich repeat protein phosphatase http://flybase.net/reports/FBgn0032749.html protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation "CT29458, dPHLPP, PP2C, CG10493" "IPR001611=Leucine-rich repeat, IPR001932=PPM-type phosphatase domain" CG10493 16-Dec-15 2015_12 viable FBgn0067346 l(3)95Ef lethal (3) 95Ef http://flybase.net/reports/FBgn0067346.html gene 16-Dec-15 2015_12 FBgn0262386 mir-306 mir-306 stem loop http://flybase.net/reports/FBgn0262386.html "FBgn0067699, FBgn0067698, FBgn0262207" miRNA_gene "mir-306*, mir-306, miR-306S, CR42914, CR33609, 306, CR33610, dme-miR-306-5p, miR-306, miR-306-star, MiR-306, dme-mir-306, mir-306S, dme-miR-306" CR42914 16-Dec-15 2015_12 "visible,lethal" "eye,wing,spermatocyte cyst" FBgn0015471 l(2)45ABa lethal (2) 45ABa http://flybase.net/reports/FBgn0015471.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0259256 C684 http://flybase.net/reports/FBgn0259256.html gene 16-Dec-15 2015_12 visible "wing,wing margin" FBgn0050121 CR30121 http://flybase.net/reports/FBgn0050121.html FBgn0046796 non_protein_coding_gene "CG30121, BcDNA:GH12850" CR30121 16-Dec-15 2015_12 viable FBgn0036104 CG6418 http://flybase.net/reports/FBgn0036104.html protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0004386=helicase activity, 0003676=nucleic acid binding" "cg6418, DmRH27" "IPR001650=Helicase, C-terminal, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain" CG6418 16-Dec-15 2015_12 ENSDARG00000037928(ddx42) WBGene00008119(C46F11.4) ENSXETG00000003245(DDX42) ENSMUSG00000020705(Ddx42) ENSG00000198231(DDX42) viable FBgn0005266 l(3)SG86 lethal (3) SG86 http://flybase.net/reports/FBgn0005266.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0040207 kat80 katanin 80 http://flybase.net/reports/FBgn0040207.html "FBgn0030730, FBgn0030732" protein_coding_gene 0008017=microtubule binding "0046843=dorsal appendage formation, 0051013=microtubule severing, 0007017=microtubule-based process" "0005829=cytosol, 0008352=katanin complex" "CG9910, Katanin80, katanin-80, CG13956, Kat80" "IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR026962=Katanin p80 subunit B1, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR028021=Katanin p80 subunit, C-terminal, IPR017986=WD40-repeat-containing domain" CG13956 16-Dec-15 2015_12 "ENSDARG00000068397,ENSDARG00000005456(katnb1)" WBGene00009825(F47G4.4) ENSXETG00000025041(katnb1) ENSMUSG00000031787(Katnb1) ENSG00000140854(KATNB1) "viable,body color defective,planar polarity defective" "mesothoracic tergum,dorsal appendage" FBgn0015336 CG15865 http://flybase.net/reports/FBgn0015336.html protein_coding_gene "anon-15Ab, unnamed" IPR024810=Mab-21 domain CG15865 16-Dec-15 2015_12 viable DRSC19733 K -0.292763599 0.37776838 0.125075029 0.636934779 1.833469416 -0.679733593 FBgn0263039 CR43334 http://flybase.net/reports/FBgn0263039.html FBgn0066118 non_protein_coding_gene pri-bantam CR43334 16-Dec-15 2015_12 visible wing FBgn0065326 l(2)SH1897 lethal (2) SH1897 http://flybase.net/reports/FBgn0065326.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003367 sf safranin http://flybase.net/reports/FBgn0003367.html FBgn0000461 gene dki 16-Dec-15 2015_12 "visible,recessive,eye color defective" "pigment cell,Malpighian tubule" FBgn0259280 C517 http://flybase.net/reports/FBgn0259280.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta,ectopic" FBgn0002004 l(2)36Bc lethal (2) 36Bc http://flybase.net/reports/FBgn0002004.html gene "l(2L)HT-10, l(2)HT-10" 16-Dec-15 2015_12 "lethal,recessive" FBgn0265809 CR44598 http://flybase.net/reports/FBgn0265809.html non_protein_coding_gene lincRNA.119 CR44598 16-Dec-15 2015_12 FBgn0265717 CR44524 http://flybase.net/reports/FBgn0265717.html non_protein_coding_gene lincRNA.976 CR44524 16-Dec-15 2015_12 FBgn0002332 l(3)87Ae lethal (3) 87Ae http://flybase.net/reports/FBgn0002332.html gene "l(3)ck12, ck12" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" Malpighian tubule FBgn0030223 CG2111 http://flybase.net/reports/FBgn0030223.html protein_coding_gene "0016920=pyroglutamyl-peptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" "0006909=phagocytosis, 0006508=proteolysis" pepCG2111 "IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG2111 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,supernumerary" FBgn0038918 CG6690 http://flybase.net/reports/FBgn0038918.html protein_coding_gene "0016971=flavin-linked sulfhydryl oxidase activity, 0016972=thiol oxidase activity" "0032504=multicellular organism reproduction, 0045454=cell redox homeostasis, 0055114=oxidation-reduction process" "0005576=extracellular region, 0005615=extracellular space" "IPR017905=ERV/ALR sulfhydryl oxidase domain, IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG6690 16-Dec-15 2015_12 WBGene00018533(F47B7.2) viable FBgn0040820 CG14146 http://flybase.net/reports/FBgn0040820.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029041 l(2)F2 lethal (2) F2 http://flybase.net/reports/FBgn0029041.html gene F2 16-Dec-15 2015_12 "lethal,recessive" FBgn0000706 fltL flight defective L http://flybase.net/reports/FBgn0000706.html gene 16-Dec-15 2015_12 flightless FBgn0051710 CG31710 http://flybase.net/reports/FBgn0051710.html protein_coding_gene EP2160 CG31710 16-Dec-15 2015_12 viable FBgn0084120 tgl tangled http://flybase.net/reports/FBgn0084120.html gene 0007417=central nervous system development 16-Dec-15 2015_12 FBgn0262398 mir-124 mir-124 stem loop http://flybase.net/reports/FBgn0262398.html "FBgn0067341, FBgn0262230" miRNA_gene "0035195=gene silencing by miRNA, 0050805=negative regulation of synaptic transmission, 0048813=dendrite morphogenesis, 0007405=neuroblast proliferation" "miR-124, miR-124a, mir-124b, mir-124, dme-mir-124, CR42937, Mir-124, dme-miR-124, mir-124a, CR33573" CR42937 16-Dec-15 2015_12 " embryonic stage , larval stage | first instar " FBgn0036835 CG14075 http://flybase.net/reports/FBgn0036835.html protein_coding_gene CG14075 16-Dec-15 2015_12 viable FBgn0004005 wdl wavoid-like http://flybase.net/reports/FBgn0004005.html gene wavoidlike 16-Dec-15 2015_12 "viable,female semi-sterile,lethal,maternal effect" "wing,wing vein L5" FBgn0034822 RpL37b Ribosomal protein L37b http://flybase.net/reports/FBgn0034822.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "CG9873, Rpl37b" "IPR001569=Ribosomal protein L37e, IPR011331=Ribosomal protein L37ae/L37e, IPR018267=Ribosomal protein L37e, conserved site, IPR011332=Zinc-binding ribosomal protein" CG9873 16-Dec-15 2015_12 "YLR185W(RPL37A),YDR500C(RPL37B)" "WBGene00012179(W01D2.1),WBGene00004451(rpl-37)" ENSG00000145592(RPL37) "viable,visible" trichogen cell FBgn0260249 GSd495 http://flybase.net/reports/FBgn0260249.html gene 16-Dec-15 2015_12 lethal FBgn0001528 l(1)11Ed lethal (1) 11Ed http://flybase.net/reports/FBgn0001528.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0082986 snoRNA:ë¬28S-2562 snoRNA:ë¬28S-2562 http://flybase.net/reports/FBgn0082986.html snoRNA_gene "chr3R:16648632..16648732, Psi 28S-2562, psi28s-2562, CR34616" CR34616 16-Dec-15 2015_12 FBgn0034440 CG10073 http://flybase.net/reports/FBgn0034440.html protein_coding_gene IPR007484=Peptidase M28 CG10073 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0051388 CG31388 http://flybase.net/reports/FBgn0051388.html "FBgn0037886, FBgn0037887, FBgn0064969" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "BcDNA:GH10523, CG17722, CG5135" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG31388 16-Dec-15 2015_12 "viable,fertile" FBgn0015955 l(1)5ABa lethal (1) 5ABa http://flybase.net/reports/FBgn0015955.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0044508 snoRNA:M snoRNA:M http://flybase.net/reports/FBgn0044508.html FBgn0052807 snoRNA_gene CR32807 CR32807 16-Dec-15 2015_12 FBgn0051856 CG31856 http://flybase.net/reports/FBgn0051856.html FBgn0062861 protein_coding_gene BcDNA:SD21618 16-Dec-15 2015_12 "viable,visible,lethal" mesothoracic tergum FBgn0000434 der deranged http://flybase.net/reports/FBgn0000434.html gene Der 16-Dec-15 2015_12 "viable,female fertile,reduced,visible,recessive,female semi-sterile" "microchaeta & adult thorax,wing,macrochaeta & adult thorax" FBgn0032889 CG9331 http://flybase.net/reports/FBgn0032889.html protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, 0051287=NAD binding" 0055114=oxidation-reduction process 0005576=extracellular region "IPR006139=D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR029753=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site, IPR016040=NAD(P)-binding domain" CG9331 16-Dec-15 2015_12 YNL274C(GOR1) ENSG00000137106(GRHPR) "viable,fertile" FBgn0023217 E(lz)53 E(lz)53 http://flybase.net/reports/FBgn0023217.html gene 16-Dec-15 2015_12 wild-type FBgn0065256 l(2)SH2109 lethal (2) SH2109 http://flybase.net/reports/FBgn0065256.html gene l(2)SH2 2109 16-Dec-15 2015_12 "lethal,recessive" FBgn0261819 CG42761 http://flybase.net/reports/FBgn0261819.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004966 larv larvaphile http://flybase.net/reports/FBgn0004966.html gene "Lar, lar" 16-Dec-15 2015_12 "lethal,recessive,maternal effect" FBgn0001451 l(1)7De lethal (1) 7De http://flybase.net/reports/FBgn0001451.html gene 16-Dec-15 2015_12 lethal FBgn0036471 CG13460 http://flybase.net/reports/FBgn0036471.html protein_coding_gene CG13460 16-Dec-15 2015_12 viable FBgn0005306 ms(1)244 male sterile (1) 244 http://flybase.net/reports/FBgn0005306.html gene 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective,behavior defective" "meiotic cell cycle | male,meiotic anaphase I & nuclear chromosome,meiotic cell cycle & spindle | male,spermatocyte & nucleus,spermatocyte & centriole,spermatid" FBgn0266987 CR45438 http://flybase.net/reports/FBgn0266987.html non_protein_coding_gene CR45438 16-Dec-15 2015_12 FBgn0262547 CG43101 http://flybase.net/reports/FBgn0262547.html protein_coding_gene CG43101 16-Dec-15 2015_12 FBgn0035187 Trh Tryptophan hydroxylase http://flybase.net/reports/FBgn0035187.html protein_coding_gene "0004510=tryptophan 5-monooxygenase activity, 0016597=amino acid binding, 0005506=iron ion binding, 0004505=phenylalanine 4-monooxygenase activity" "0030431=sleep, 0042427=serotonin biosynthetic process, 0045187=regulation of circadian sleep/wake cycle, sleep, 0006568=tryptophan metabolic process, 0055114=oxidation-reduction process" "CT9937, TRH, dTrh, tryptophan hydroxylase, DTRH, CG9122, TRHn, DTPHu" "IPR018301=Aromatic amino acid hydroxylase, iron/copper binding site, IPR019773=Tyrosine 3-monooxygenase-like, IPR005963=Tryptophan 5-monooxygenase, IPR019774=Aromatic amino acid hydroxylase, C-terminal, IPR002912=ACT domain, IPR001273=Aromatic amino acid hydroxylase" CG9122 16-Dec-15 2015_12 "ENSDARG00000029432(tph1a),ENSDARG00000036082(tph1b),ENSDARG00000057239(tph2)" WBGene00006600(tph-1) ENSXETG00000018984(TPH1) "ENSMUSG00000040046(Tph1),ENSMUSG00000006764(Tph2)" "ENSG00000129167(TPH1),ENSG00000139287(TPH2)" "behavior defective,male,viable,fertile,feeding behavior defective,smell perception defective,neuroanatomy defective,partially lethal - majority die,some die during larval stage" FBgn0065327 l(2)SH1895 lethal (2) SH1895 http://flybase.net/reports/FBgn0065327.html gene l(2)SH2 1895 16-Dec-15 2015_12 "lethal,recessive" FBgn0262151 esi-4 endogenous siRNA 4 http://flybase.net/reports/FBgn0262151.html gene esiRNA-sl-4 16-Dec-15 2015_12 FBgn0065834 l(2)SH0342 lethal (2) SH0342 http://flybase.net/reports/FBgn0065834.html gene l(2)SH2 0342 16-Dec-15 2015_12 "lethal,recessive" FBgn0028850 CG15260 http://flybase.net/reports/FBgn0028850.html protein_coding_gene 0022008=neurogenesis BG:DS07851.8 CG15260 16-Dec-15 2015_12 "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0267711 CR46044 http://flybase.net/reports/FBgn0267711.html non_protein_coding_gene CR46044 16-Dec-15 2015_12 FBgn0267056 CR45500 http://flybase.net/reports/FBgn0267056.html non_protein_coding_gene CR45500 16-Dec-15 2015_12 FBgn0034186 CG8950 http://flybase.net/reports/FBgn0034186.html protein_coding_gene "IPR001440=Tetratricopeptide repeat 1, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG8950 16-Dec-15 2015_12 YGR047C(TFC4) WBGene00014114(tag-315) ENSXETG00000027469(GTF3C3) ENSMUSG00000041303(Gtf3c3) ENSG00000119041(GTF3C3) viable FBgn0022351 anon-25Dc anon-25Dc http://flybase.net/reports/FBgn0022351.html gene e4 16-Dec-15 2015_12 FBgn0003000 On Open http://flybase.net/reports/FBgn0003000.html gene 16-Dec-15 2015_12 viable wing FBgn0267953 CR46233 http://flybase.net/reports/FBgn0267953.html non_protein_coding_gene lincRNA.861 CR46233 16-Dec-15 2015_12 FBgn0024502 Aco Accordion http://flybase.net/reports/FBgn0024502.html gene 0007370=ventral furrow formation 16-Dec-15 2015_12 FBgn0084704 836 836 http://flybase.net/reports/FBgn0084704.html gene 16-Dec-15 2015_12 FBgn0034692 CG13502 http://flybase.net/reports/FBgn0034692.html protein_coding_gene "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG13502 16-Dec-15 2015_12 viable FBgn0000493 drb dark red brown http://flybase.net/reports/FBgn0000493.html gene 16-Dec-15 2015_12 "eye color defective,cold sensitive" "pigment cell,cold sensitive" FBgn0030813 CG4949 http://flybase.net/reports/FBgn0030813.html protein_coding_gene CG4949 16-Dec-15 2015_12 viable FBgn0086205 S(ls)7 http://flybase.net/reports/FBgn0086205.html gene 16-Dec-15 2015_12 FBgn0085245 CG34216 http://flybase.net/reports/FBgn0085245.html protein_coding_gene CG34216 16-Dec-15 2015_12 FBgn0039916 Ekar Eye-enriched kainate receptor http://flybase.net/reports/FBgn0039916.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity" "0071632=optomotor response, 0035249=synaptic transmission, glutamatergic, 0071484=cellular response to light intensity, 0016057=regulation of membrane potential in photoreceptor cell, 0060025=regulation of synaptic activity, 0006811=ion transport" 0005886=plasma membrane "CT36399, CG9935, ekar, DmelCG9935, eye-enriched kainate receptor" "IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region, IPR001508=Ionotropic glutamate receptor, metazoa" CG9935 16-Dec-15 2015_12 WBGene00001616(glr-5) viable DRSC24931 K -0.052055398 -0.620377827 -0.309879735 0.381367144 0.369896691 2.03668539 FBgn0263647 CG43638 http://flybase.net/reports/FBgn0263647.html protein_coding_gene CG43638 16-Dec-15 2015_12 FBgn0026388 Or46a Odorant receptor 46a http://flybase.net/reports/FBgn0026388.html "FBgn0026387, FBgn0053478" protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "Odorant receptor 46b, 46b, Or46F.1, CG33478, Olfactory receptor 46F.1, Or46F.2, AN9, dor19, Or46aA, CG17849, Or46aa, Or46aB, 46F.1, DOR20, Or19, AN8, Or46b, DOR46F.2, DOR19, 46a, CG17848, Olfactory receptor 46F.2, DOR46F.1" "IPR004117=Olfactory receptor, Drosophila" CG33478 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC07490 K 0.423095351 0.1471332 -0.145503299 0.502398527 2.665955511 0.141930693 FBgn0065977 iab-8E.s iab-8E.s http://flybase.net/reports/FBgn0065977.html gene "IAB8, 8E, iab-8E s, IAB-8E s" 16-Dec-15 2015_12 FBgn0031536 Cog3 Cog3 http://flybase.net/reports/FBgn0031536.html protein_coding_gene 0008565=protein transporter activity "0006886=intracellular protein transport, 0006891=intra-Golgi vesicle-mediated transport, 0033227=dsRNA transport, 0022008=neurogenesis, 0006888=ER to Golgi vesicle-mediated transport, 0007112=male meiosis cytokinesis" "0016020=membrane, 0017119=Golgi transport complex, 0005801=cis-Golgi network" "COG3, dCOG3, CG3248, SEC34, CG 3248" "IPR007265=Conserved oligomeric Golgi complex, subunit 3" CG3248 16-Dec-15 2015_12 ENSDARG00000053504(cog3) YER157W(COG3) WBGene00022121(cogc-3) ENSMUSG00000034893(Cog3) ENSG00000136152(COG3) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC00585 E 0.517332493 0.604583619 1.787207642 -1.055849886 0.306363113 0.396189865 FBgn0034264 CG10933 http://flybase.net/reports/FBgn0034264.html protein_coding_gene IPR001452=SH3 domain CG10933 16-Dec-15 2015_12 WBGene00007742(C26C6.8) "lethal,partially lethal - majority die,visible,recessive" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0005040 E(tuh-1) Enhancer of tumorous head 1 http://flybase.net/reports/FBgn0005040.html gene 16-Dec-15 2015_12 FBgn0004129 l(2)43Cc lethal (2) 43Cc http://flybase.net/reports/FBgn0004129.html gene 16-Dec-15 2015_12 lethal FBgn0015318 U2af65 U2 small nuclear riboprotein auxiliary factor 65 http://flybase.net/reports/FBgn0015318.html FBgn0012029 gene 0008187=poly-pyrimidine tract binding "U2AF, U2AF[65]" 16-Dec-15 2015_12 FBgn0046888 CG31750 http://flybase.net/reports/FBgn0046888.html FBgn0051750 protein_coding_gene 0008527=taste receptor activity "Gr36d, CG31750" CG31750 16-Dec-15 2015_12 viable FBgn0033404 Or45a Odorant receptor 45a http://flybase.net/reports/FBgn0033404.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR58, CG1978, 45C.1, 45a" "IPR004117=Olfactory receptor, Drosophila" CG1978 16-Dec-15 2015_12 smell perception defective FBgn0028712 MI02 MI02 http://flybase.net/reports/FBgn0028712.html gene v(3)03847 16-Dec-15 2015_12 "visible,recessive" FBgn0027845 Bro::Hsap\MYH11 Bro::Hsap\MYH11 http://flybase.net/reports/FBgn0027845.html engineered_fusion_gene Bro::SMMHC 16-Dec-15 2015_12 visible "eye,ommatidium" FBgn0035547 CG15022 http://flybase.net/reports/FBgn0035547.html FBgn0062451 protein_coding_gene BcDNA:RE24507 CG15022 16-Dec-15 2015_12 viable DRSC08476 IEK 0.144866205 -2.179511784 0.285832959 -2.084503675 -2.153266597 -0.980194736 FBgn0267892 CR46180 http://flybase.net/reports/FBgn0267892.html pseudogene_attribute CG12717-related CR46180 16-Dec-15 2015_12 FBgn0034501 CG13868 http://flybase.net/reports/FBgn0034501.html FBgn0045891 protein_coding_gene anon-WO0153538.60 CG13868 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0066075 Su(rux)2B Su(rux)2B http://flybase.net/reports/FBgn0066075.html gene 0016330=second mitotic wave involved in compound eye morphogenesis 16-Dec-15 2015_12 FBgn0013756 Mtor Megator http://flybase.net/reports/FBgn0013756.html "FBgn0019919, FBgn0022212" protein_coding_gene "0043021=ribonucleoprotein complex binding, 0031490=chromatin DNA binding" "0000022=mitotic spindle elongation, 0034976=response to endoplasmic reticulum stress, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007094=mitotic spindle assembly checkpoint, 0010965=regulation of mitotic sister chromatid separation, 0007346=regulation of mitotic cell cycle, 0006325=chromatin organization, 0006338=chromatin remodeling, 0051225=spindle assembly, 0006606=protein import into nucleus" "0072686=mitotic spindle, 0034399=nuclear periphery, 0005634=nucleus, 0005819=spindle, 0005643=nuclear pore, 0051233=spindle midzone, 1990047=spindle matrix, 0005635=nuclear envelope, 0005654=nucleoplasm, 0005719=nuclear euchromatin" "MTOR, CG8274, lethal (2) k03905, Tpr, Bx34, l(2)k03905, TPR, Megator" IPR012929=Nucleoprotein TPR/MLP1 CG8274 16-Dec-15 2015_12 "ENSDARG00000016630(tprb),ENSDARG00000052914,ENSDARG00000014538(LOC100005683)" "YIL149C(MLP2),YKR095W(MLP1)" ENSXETG00000017390(TPR) ENSMUSG00000006005(Tpr) ENSG00000047410(TPR) embryonic stage&&larval stage&&adult stage "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "male germline cell,cyst progenitor cell,germline stem cell,trichogen cell,mesothoracic tergum" FBgn0004581 bgcn benign gonial cell neoplasm http://flybase.net/reports/FBgn0004581.html "FBgn0000965, FBgn0001096, FBgn0003066, FBgn0026784, FBgn0034917, FBgn0050170" protein_coding_gene "0004386=helicase activity, 0000900=translation repressor activity, nucleic acid binding" "0048477=oogenesis, 0007281=germ cell development, 0098730=male germline stem cell symmetric division, 0007283=spermatogenesis, 0007284=spermatogonial cell division, 0045478=fusome organization, 0007282=cystoblast division, 0035212=cell competition in a multicellular organism, 0007140=male meiosis, 0017148=negative regulation of translation, 0030718=germ-line stem cell maintenance" "BGCN, b(2)gcn, unnamed, CG10330, benign gonial, fs(2)eo6, gcn, b(2)cgn, PNBP, fs(2)eoQS2, Bgcn, cell neoplasm, benign-(2)-gonial-cell-neoplasm, gonial-cell-neoplasm, CG10331, peppercorn, Putative nuclear binding protein, ben(2)gcn, fs(2)eo-C, CG30170, pep, benign gonial cell neoplasia, bcgn, cg10331" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR011709=Domain of unknown function DUF1605, IPR007502=Helicase-associated domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG30170 16-Dec-15 2015_12 " adult stage | male , adult stage && oogenesis stage " " female germline stem cell

, cystoblast

, cystocyte

, germarium

" "male sterile,recessive,female sterile,tumorigenic,viable,hyperplasia,cytokinesis defective,meiotic cell cycle defective" "gonad,germline stem cell,germline cell,male germline stem cell,female germline stem cell,ovary,stem cell fusome,testis,germarium,cystocyte,fusome" FBgn0031012 CG8051 http://flybase.net/reports/FBgn0031012.html FBgn0065991 protein_coding_gene 0015355=secondary active monocarboxylate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "EP(X)1550, anon-WO03002137.1" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG8051 16-Dec-15 2015_12 viable FBgn0267359 GS16203 http://flybase.net/reports/FBgn0267359.html gene 16-Dec-15 2015_12 FBgn0065830 l(2)SH0353 lethal (2) SH0353 http://flybase.net/reports/FBgn0065830.html gene l(2)SH2 0353 16-Dec-15 2015_12 "lethal,recessive" FBgn0005519 l(2)36Db lethal (2) 36Db http://flybase.net/reports/FBgn0005519.html gene l(2)36D6 16-Dec-15 2015_12 FBgn0036941 CG7335 http://flybase.net/reports/FBgn0036941.html FBgn0062514 protein_coding_gene "0008865=fructokinase activity, 0004454=ketohexokinase activity" 0046835=carbohydrate phosphorylation 0005737=cytoplasm BcDNA:AT09463 "IPR011611=Carbohydrate kinase PfkB, IPR029056=Ribokinase-like, IPR006696=Protein of unknown function DUF423" CG7335 16-Dec-15 2015_12 viable FBgn0265509 CR44371 http://flybase.net/reports/FBgn0265509.html non_protein_coding_gene CR44371 16-Dec-15 2015_12 FBgn0012299 Abd-B::Dfd Abd-B::Dfd http://flybase.net/reports/FBgn0012299.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive" "larval abdominal segment,anterior,filzkorper,ectopic,embryonic abdominal segment,heat sensitive,embryonic mesothoracic segment,embryonic metathoracic segment,T1 beard,spiracular sense organ (obsolete FBbt00000431),embryonic prothoracic segment,abdominal segment,Kolbchen,denticle belt,embryonic head" FBgn0058125 CG40125 http://flybase.net/reports/FBgn0058125.html protein_coding_gene 16-Dec-15 2015_12 DRSC21010 E 0.123257854 0.616020449 1.695077499 -6.089945634 FBgn0027226 l(1)G0307 lethal (1) G0307 http://flybase.net/reports/FBgn0027226.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0250837 dUTPase Deoxyuridine triphosphatase http://flybase.net/reports/FBgn0250837.html "FBgn0013349, FBgn0027890, FBgn0066921" protein_coding_gene 0004170=dUTP diphosphatase activity 0046080=dUTP metabolic process "0005886=plasma membrane, 0005634=nucleus, 0005737=cytoplasm" "CG4584, UTPase, LD08534, BcDNA:LD08534, anon-SAGE:Wang-077" "IPR029054=dUTPase-like, IPR008181=Deoxyuridine triphosphate nucleotidohydrolase, IPR008180=Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase" CG4584 16-Dec-15 2015_12 ENSDARG00000007374 YBR252W(DUT1) ENSXETG00000026521(DUT) ENSMUSG00000027203(Dut) ENSG00000128951(DUT) FBgn0013566 l(3)78Ab lethal (3) 78Ab http://flybase.net/reports/FBgn0013566.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011808 l(3)s2714 lethal (3) s2714 http://flybase.net/reports/FBgn0011808.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005680 disf disordered facets http://flybase.net/reports/FBgn0005680.html gene 0048749=compound eye development dif 16-Dec-15 2015_12 "visible,recessive" "eye,ommatidium,eye photoreceptor cell,supernumerary,retina" FBgn0265043 CR44160 http://flybase.net/reports/FBgn0265043.html non_protein_coding_gene CR44160 16-Dec-15 2015_12 FBgn0011630 l(2)T57d12 lethal (2) T57d12 http://flybase.net/reports/FBgn0011630.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0037944 CG6923 http://flybase.net/reports/FBgn0037944.html protein_coding_gene 0008270=zinc ion binding "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG6923 16-Dec-15 2015_12 ENSXETG00000010842(RNF111) ENSMUSG00000032217(Rnf111) ENSG00000157450(RNF111) viable FBgn0265185 CG44250 http://flybase.net/reports/FBgn0265185.html FBgn0033786 protein_coding_gene CG3884 "IPR006616=DM9 repeat, IPR024518=Domain of unknown function DUF3421" CG44250 16-Dec-15 2015_12 viable FBgn0011965 tRNA:R:83AB transfer RNA:arg:83AB http://flybase.net/reports/FBgn0011965.html "FBgn0011947, FBgn0051593, FBgn0060077" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033431=CGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "unnamed, tRNA:R:TCG:AE002681, CR31593, tRNA:arg83AB, tRNA-Arg, AE002681.trna1-ArgTCG, chr3R.trna1-ArgTCG, tRNA[arg], tRNA:arg1, tRNA:R1, transfer RNA:arg1" CR31593 16-Dec-15 2015_12 FBgn0001787 l(1)M96 lethal (1) M96 http://flybase.net/reports/FBgn0001787.html gene 16-Dec-15 2015_12 lethal FBgn0052522 CG32522 http://flybase.net/reports/FBgn0052522.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032909 CG9266 http://flybase.net/reports/FBgn0032909.html FBgn0047270 protein_coding_gene BcDNA:GM06547 16-Dec-15 2015_12 FBgn0026385 Or47b Odorant receptor 47b http://flybase.net/reports/FBgn0026385.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "OR 47b, 47E.2, DOR47E.2, DOR25, Or47E.2, Olfactory receptor 47E.2, OR47b, or47b, CG13206, 47b" "IPR004117=Olfactory receptor, Drosophila" CG13206 16-Dec-15 2015_12 viable FBgn0000597 E(var)87F Enhancer of variegation 3 http://flybase.net/reports/FBgn0000597.html FBgn0000598 gene "E-var(3)3, E(var)3-3, E(var)8, E(var)3" 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0263481 snoRNA:lola-b http://flybase.net/reports/FBgn0263481.html snoRNA_gene CR43596 16-Dec-15 2015_12 FBgn0028982 Spt6 Spt6 http://flybase.net/reports/FBgn0028982.html "FBgn0026691, FBgn0028682" protein_coding_gene "0003682=chromatin binding, 0003677=DNA binding" "0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0002805=regulation of antimicrobial peptide biosynthetic process" "0005705=polytene chromosome interband, 0005703=polytene chromosome puff, 0005634=nucleus, 0035363=histone locus body, 0000176=nuclear exosome (RNase complex), 0035101=FACT complex, 0008023=transcription elongation factor complex, 0035327=transcriptionally active chromatin" "spt6, l(1)G0063, dSpt6, CG12225, dspt6, SPT6, Dspt6, spt 6" "IPR012337=Ribonuclease H-like domain, IPR022967=RNA-binding domain, S1, IPR023097=Tex RuvX-like domain, IPR017072=Transcription elongation factor Spt6, IPR003029=S1 domain, IPR006641=YqgF/RNase H-like domain, IPR000980=SH2 domain, IPR028083=Spt6 acidic, N-terminal domain, IPR023323=Tex-like domain, IPR028088=Helix-turn-helix DNA-binding domain of Spt6, IPR010994=RuvA domain 2-like, IPR028231=Transcription elongation factor Spt6, YqgF domain, IPR027999=Death-like domain of Spt6, IPR012340=Nucleic acid-binding, OB-fold" CG12225 16-Dec-15 2015_12 ENSDARG00000006524(supt6h) YGR116W(SPT6) WBGene00001259(emb-5) ENSMUSG00000002052(Supt6h) ENSG00000109111(SUPT6H) "viable,lethal - all die before end of embryonic stage,lethal,recessive,some die during embryonic stage,melanotic mass phenotype,visible,lethal - all die before end of larval stage,some die during larval stage" "female germline cell,cuticle | pharate adult stage,abdomen | pharate adult stage,trichome | pharate adult stage,melanotic mass | pharate adult stage" DRSC18836 IEK -1.50883966 3.049083373 -0.259982998 1.840579737 2.792518087 2.602204713 FBgn0031465 CG3123 http://flybase.net/reports/FBgn0031465.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi7295901, gi21064005" "IPR004245=Protein of unknown function DUF229, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain" CG3123 16-Dec-15 2015_12 viable FBgn0262816 CG43187 http://flybase.net/reports/FBgn0262816.html protein_coding_gene "DMG8-chr2R.23.004, lincRNA.322" CG43187 16-Dec-15 2015_12 FBgn0029745 Rpn13R Regulatory particle non-ATPase 13-related http://flybase.net/reports/FBgn0029745.html protein_coding_gene 0043130=ubiquitin binding 0006511=ubiquitin-dependent protein catabolic process "0008541=proteasome regulatory particle, lid subcomplex, 0005634=nucleus, 0005737=cytoplasm" CG6789 "IPR006773=26S proteasome complex ubiquitin receptor, subunit Rpn13" CG6789 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0267748 CR46079 http://flybase.net/reports/FBgn0267748.html non_protein_coding_gene CR46079 16-Dec-15 2015_12 FBgn0002139 l(2)K300 lethal (2) K300 http://flybase.net/reports/FBgn0002139.html gene 16-Dec-15 2015_12 lethal FBgn0033777 CG17574 http://flybase.net/reports/FBgn0033777.html FBgn0047053 protein_coding_gene BcDNA:RH03863 CG17574 16-Dec-15 2015_12 "viable,fertile" FBgn0005339 RD(2) Recovery Disruptor on 2 http://flybase.net/reports/FBgn0005339.html gene 16-Dec-15 2015_12 FBgn0015999 l(3)13m-320 lethal (3) 13m-320 http://flybase.net/reports/FBgn0015999.html gene 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0069068 27-25 27-25 http://flybase.net/reports/FBgn0069068.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" FBgn0037424 Osi15 Osiris 15 http://flybase.net/reports/FBgn0037424.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG1157, osi15" IPR012464=Protein of unknown function DUF1676 CG1157 16-Dec-15 2015_12 FBgn0021984 l(2)k09848 lethal (2) k09848 http://flybase.net/reports/FBgn0021984.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035195 Sac1 Sac1 http://flybase.net/reports/FBgn0035195.html protein_coding_gene "0052866=phosphatidylinositol phosphate phosphatase activity, 0052744=phosphatidylinositol monophosphate phosphatase activity, 0016791=phosphatase activity" "0060074=synapse maturation, 0046488=phosphatidylinositol metabolic process, 0046856=phosphatidylinositol dephosphorylation, 0046664=dorsal closure, amnioserosa morphology change, 0031122=cytoplasmic microtubule organization, 0046329=negative regulation of JNK cascade, 0016199=axon midline choice point recognition, 0008088=axon cargo transport" "0012505=endomembrane system, 0071683=sensory dendrite, 0030424=axon, 0043025=neuronal cell body, 0005789=endoplasmic reticulum membrane" "CG9128, sac1, dsac1, suppressor of actin-1, l(3)2107" IPR002013=SAC domain CG9128 16-Dec-15 2015_12 "ENSDARG00000015290(si:ch211-222e23.8),ENSDARG00000059806(zgc:158642)" YKL212W(SAC1) WBGene00009264(sac-1) ENSXETG00000011975(SACM1L) ENSMUSG00000025240(Sacm1l) ENSG00000211456(SACM1L) "visible,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,partially lethal,increased cell death" "eye,embryonic/first instar larval cuticle,dorsal,dorsal hair,amnioserosa,NMJ bouton,ommatidium,interommatidial bristle,NMJ bouton | larval stage" FBgn0005573 l(3)85Ei lethal (3) 85Ei http://flybase.net/reports/FBgn0005573.html gene 16-Dec-15 2015_12 lethal FBgn0265661 CR44468 http://flybase.net/reports/FBgn0265661.html non_protein_coding_gene lincRNA.345 CR44468 16-Dec-15 2015_12 FBgn0000336 cmt comet http://flybase.net/reports/FBgn0000336.html gene 16-Dec-15 2015_12 "lethal,recessive" "wing & trichome,cuticle" FBgn0010139 l(2)DTS20 lethal (2) DTS20 http://flybase.net/reports/FBgn0010139.html gene DTS-L20 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive" "adult abdomen,dorsal" FBgn0000579 Eno Enolase http://flybase.net/reports/FBgn0000579.html "FBgn0045789, FBgn0045874" protein_coding_gene "0004634=phosphopyruvate hydratase activity, 0000287=magnesium ion binding" 0006096=glycolytic process "0005737=cytoplasm, 0005811=lipid particle, 0000015=phosphopyruvate hydratase complex, 0005886=plasma membrane" "ENOA, phosphopyruvate hydratase, BEST:LD15491, Eno2, CG17654, anon-WO0153538.76, eno, T18, enolase, CT32526" "IPR020811=Enolase, N-terminal, IPR029065=Enolase C-terminal domain-like, IPR020810=Enolase, C-terminal, IPR000941=Enolase, IPR029017=Enolase N-terminal domain-like, IPR020809=Enolase, conserved site" CG17654 16-Dec-15 2015_12 "ENSDARG00000022456(eno1),ENSDARG00000013750(zgc:73056),ENSDARG00000039007(wu:fj24f12),ENSDARG00000014287(eno2)" "YGR254W(ENO1),YHR174W(ENO2),YPL281C(ERR2),YOR393W(ERR1),YMR323W(ERR3)" WBGene00011884(enol-1) ENSXETG00000011897(Q6P8E1_XENTR) "ENSMUSG00000064193,ENSMUSG00000059040(Gm5506),ENSMUSG00000063524(Eno1),ENSMUSG00000060600(Eno3),ENSMUSG00000004267(Eno2)" "ENSG00000074800(ENO1),ENSG00000111674(ENO2),ENSG00000108515(ENO3),ENSG00000215809" larval stage | third instar dorsal mesothoracic disc

"lethal,viable,fertile" FBgn0065961 l(2)SH0032 lethal (2) SH0032 http://flybase.net/reports/FBgn0065961.html gene l(2)SH2 0032 16-Dec-15 2015_12 "lethal,recessive" FBgn0004976 Apart Apart http://flybase.net/reports/FBgn0004976.html gene "apt, Apt" 16-Dec-15 2015_12 "lethal,recessive,visible,dominant,viable,good,fertile" wing FBgn0028237 l(3)S002309 lethal (3) S002309 http://flybase.net/reports/FBgn0028237.html gene 0023/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0041112 l(3)cl-R3 lethal (3) cell lethal R3 http://flybase.net/reports/FBgn0041112.html gene cl3R3 16-Dec-15 2015_12 "lethal,cell lethalcell lethal,somatic clone" FBgn0065873 l(2)SH0251 lethal (2) SH0251 http://flybase.net/reports/FBgn0065873.html gene l(2)SH2 0251 16-Dec-15 2015_12 "lethal,recessive" FBgn0259391 C432 http://flybase.net/reports/FBgn0259391.html gene 16-Dec-15 2015_12 "visible,lethal" wing hair FBgn0262827 CG43198 http://flybase.net/reports/FBgn0262827.html protein_coding_gene DMG6-MB6.chrX.13.005 CG43198 16-Dec-15 2015_12 FBgn0038865 cDIP Common Dpr-interacting protein http://flybase.net/reports/FBgn0038865.html protein_coding_gene "common DIP, DIPc, 10824, CT11359, CG10824" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG10824 16-Dec-15 2015_12 ENSMUSG00000070056(Mfhas1) "partially lethal - majority die,some die during pupal stage" FBgn0002568 luc luckenhaft http://flybase.net/reports/FBgn0002568.html gene 0007349=cellularization 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle,embryonic head,embryonic segment" FBgn0029506 Tsp42Ee Tetraspanin 42Ee http://flybase.net/reports/FBgn0029506.html "FBgn0033126, FBgn0062212" protein_coding_gene "0016021=integral component of membrane, 0045169=fusome" "CG10106, tetraspanin 42E, Dm.Tsp42Ee, Tetraspanin, anon-WO0118547.151, BcDNA:LD16071" "IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin" CG10106 16-Dec-15 2015_12 viable FBgn0000872 fs(1)M68 female sterile (1) M68 http://flybase.net/reports/FBgn0000872.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0035647 CG10486 http://flybase.net/reports/FBgn0035647.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG10486 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "viable,fertile" FBgn0036282 Smyd4 SET and MYND domain protein 4 http://flybase.net/reports/FBgn0036282.html protein_coding_gene "0042826=histone deacetylase binding, 0005515=protein binding" "0007562=eclosion, 0010629=negative regulation of gene expression" "0005737=cytoplasm, 0005634=nucleus" "dSmyd4, CG14122, Smyd4" "IPR001214=SET domain, IPR011990=Tetratricopeptide-like helical domain" CG14122 16-Dec-15 2015_12 ENSXETG00000013541(SMYD4) ENSMUSG00000018809(Smyd4) ENSG00000186532(SMYD4) "viable,fertile,lethal,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0051678 CG31678 http://flybase.net/reports/FBgn0051678.html "FBgn0032874, FBgn0032875" protein_coding_gene 0046331=lateral inhibition "CG17466, 38D.30, CG17465" "IPR012919=SUN domain, IPR008979=Galactose-binding domain-like" CG31678 16-Dec-15 2015_12 ENSDARG00000016532(si:ch211-184m19.1) ENSXETG00000000531(C1orf9) ENSG00000094975(C1orf9) "viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0031146 CG15449 http://flybase.net/reports/FBgn0031146.html protein_coding_gene CG15449 16-Dec-15 2015_12 viable FBgn0040990 CG15156 http://flybase.net/reports/FBgn0040990.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085213 CG34184 http://flybase.net/reports/FBgn0085213.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG34184 16-Dec-15 2015_12 FBgn0262983 CG43291 http://flybase.net/reports/FBgn0262983.html protein_coding_gene CG43291 16-Dec-15 2015_12 FBgn0259609 B1501 http://flybase.net/reports/FBgn0259609.html gene 16-Dec-15 2015_12 visible "tarsal segment,mediproboscis,proboscis" FBgn0263143 vret vreteno http://flybase.net/reports/FBgn0263143.html "FBgn0069073, FBgn0039018" protein_coding_gene 0005515=protein binding "0007293=germarium-derived egg chamber formation, 0048477=oogenesis, 0010526=negative regulation of transposition, RNA-mediated, 0060966=regulation of gene silencing by RNA, 0034587=piRNA metabolic process" "0005737=cytoplasm, 0070725=Yb body" "vretano, CG4771, avocado, Vretano" IPR002999=Tudor domain CG4771 16-Dec-15 2015_12 FBgn0061063 l(3)S022122b lethal (3) S022122b http://flybase.net/reports/FBgn0061063.html gene 0221/22 16-Dec-15 2015_12 lethal FBgn0085236 CG34207 http://flybase.net/reports/FBgn0085236.html protein_coding_gene CG34207 16-Dec-15 2015_12 FBgn0011957 tRNA:R2:42Ac transfer RNA:arg2:42Ac http://flybase.net/reports/FBgn0011957.html "FBgn0003757, FBgn0011947, FBgn0050306, FBgn0050512, FBgn0060090" tRNA_gene "0033429=CGU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "Arg-tRNA, tRNA[arg], tRNA:R1, transfer RNA:arg1, tRNA:arg1, AE002769.trna12-ArgACG, CR30306, chr2R.trna3-ArgACG, tRNA:R:ACG:AE002769-c, CR30512, tRNA[Arg][[2]], tRNA:arg2:42Ac" CR30512 16-Dec-15 2015_12 FBgn0010693 l(2)s4199 lethal (2) s4199 http://flybase.net/reports/FBgn0010693.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259341 C192 http://flybase.net/reports/FBgn0259341.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0261068 LSm7 http://flybase.net/reports/FBgn0261068.html "FBgn0032599, FBgn0062904, FBgn0259793" protein_coding_gene "0003723=RNA binding, 0005515=protein binding" "0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" "0005688=U6 snRNP, 0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0005732=small nucleolar ribonucleoprotein complex" "BcDNA:RH73529, CG13277" "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type, IPR017132=Sm-like protein Lsm7/snRNP-G" CG13277 16-Dec-15 2015_12 ENSDARG00000058328(lsm7) YNL147W(LSM7) WBGene00003081(lsm-7) ENSXETG00000022166(LSM7) "ENSMUSG00000064317(Gm10146),ENSMUSG00000035215(Lsm7)" DRSC02251 K 0.204611123 1.229106634 0.286358835 1.460116065 -1.720146305 0.118562524 FBgn0000943 fs(2)A13 female sterile (2) A13 http://flybase.net/reports/FBgn0000943.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0036044 Zasp67 http://flybase.net/reports/FBgn0036044.html protein_coding_gene 0030239=myofibril assembly CG14168 "IPR017351=LIM and senescent cell antigen-like-containing domain protein 1, IPR001478=PDZ domain" CG14168 16-Dec-15 2015_12 "ENSMUSG00000028273(Pdlim5),ENSMUSG00000021493(Pdlim7),ENSMUSG00000021798(Ldb3)" "viable,flight defective" FBgn0259276 EP-67 http://flybase.net/reports/FBgn0259276.html gene 16-Dec-15 2015_12 "visible,planar polarity defective,lethal" wing FBgn0015426 l(1)1CDc lethal (1) 1CDc http://flybase.net/reports/FBgn0015426.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037994 CG4810 http://flybase.net/reports/FBgn0037994.html protein_coding_gene 0003743=translation initiation factor activity "0006413=translational initiation, 0006446=regulation of translational initiation" 0005852=eukaryotic translation initiation factor 3 complex "eIF3-S7, 149735_at" IPR007783=Eukaryotic translation initiation factor 3 subunit D CG4810 16-Dec-15 2015_12 ENSDARG00000021257(eif3d) WBGene00001227(eif-3.D) ENSXETG00000027259(eif3s7) ENSMUSG00000016554(Eif3d) ENSG00000100353(EIF3D) viable FBgn0004125 l(2)43Bd lethal (2) 43Bd http://flybase.net/reports/FBgn0004125.html gene 43Bd 16-Dec-15 2015_12 "lethal,recessive" FBgn0041713 yellow-c yellow-c http://flybase.net/reports/FBgn0041713.html "FBgn0026296, FBgn0028922, FBgn0032559" protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "CG4182, anon-EST:ParkEST125, yell-c, BG:DS00929.8" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG4182 16-Dec-15 2015_12 FBgn0030819 CG8926 http://flybase.net/reports/FBgn0030819.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040942 CG12643 http://flybase.net/reports/FBgn0040942.html protein_coding_gene CG12643 16-Dec-15 2015_12 viable FBgn0058000 CG40000 http://flybase.net/reports/FBgn0058000.html FBan0040000 protein_coding_gene 16-Dec-15 2015_12 FBgn0037796 CG12814 http://flybase.net/reports/FBgn0037796.html FBgn0040542 protein_coding_gene CG12815 IPR001507=Zona pellucida domain CG12814 16-Dec-15 2015_12 viable FBgn0259658 B1509 http://flybase.net/reports/FBgn0259658.html gene 16-Dec-15 2015_12 visible "tarsal segment,unguis,antennal segment,arista,wing,scutellum" FBgn0060607 l(3)S090605 lethal (3) S090605 http://flybase.net/reports/FBgn0060607.html gene 0906/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262969 CR43280 http://flybase.net/reports/FBgn0262969.html non_protein_coding_gene lincRNA.605 CR43280 16-Dec-15 2015_12 FBgn0014066 Su(tor)3-333 Su(tor)3-333 http://flybase.net/reports/FBgn0014066.html gene 16-Dec-15 2015_12 FBgn0264636 conjoined conjoined http://flybase.net/reports/FBgn0264636.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0267073 CR45517 http://flybase.net/reports/FBgn0267073.html non_protein_coding_gene CR45517 16-Dec-15 2015_12 FBgn0064172 l(2)c855 lethal (2) c855 http://flybase.net/reports/FBgn0064172.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0024609 olfJ106 olfactory J106 http://flybase.net/reports/FBgn0024609.html gene 16-Dec-15 2015_12 smell perception defective FBgn0082614 Su(PDS)P80 Su(PDS)P80 http://flybase.net/reports/FBgn0082614.html gene 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation" FBgn0040330 EY2-8 EY2-8 http://flybase.net/reports/FBgn0040330.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010066 M(3)32l M(3)32l http://flybase.net/reports/FBgn0010066.html gene 16-Dec-15 2015_12 FBgn0036847 CG11577 http://flybase.net/reports/FBgn0036847.html FBgn0062094 protein_coding_gene 0012505=endomembrane system anon-WO0118547.323 IPR021852=Domain of unknown function DUF3456 CG11577 16-Dec-15 2015_12 ENSDARG00000055797(cnpy4) WBGene00007531(C11H1.7) ENSMUSG00000036968(Cnpy4) ENSG00000166997(CNPY4) viable FBgn0016968 wan wanderer http://flybase.net/reports/FBgn0016968.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 "lethal,recessive" peripheral nervous system FBgn0264552 CG43931 http://flybase.net/reports/FBgn0264552.html protein_coding_gene CG43931 16-Dec-15 2015_12 FBgn0016701 Rab4 Rab4 http://flybase.net/reports/FBgn0016701.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032482=Rab protein signal transduction, 0015031=protein transport, 0016192=vesicle-mediated transport, 0006897=endocytosis" "0055037=recycling endosome, 0005886=plasma membrane, 0043025=neuronal cell body, 0031982=vesicle, 0045202=synapse" "RAB4c, CG 4921, DmRab4, rab4, CG4921, Rab-protein 4, Q7KY04, DRAB4" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR003579=Small GTPase superfamily, Rab type" CG4921 16-Dec-15 2015_12 "ENSDARG00000012177(zgc:101015),ENSDARG00000019144(rab4a)" ENSXETG00000002590(rab4b) "ENSMUSG00000019478(Rab4a),ENSMUSG00000053291(Rab4b)" "ENSG00000168118(RAB4A),ENSG00000167578(RAB4B)" "viable,neuroanatomy defective" embryonic/larval glial cell FBgn0037501 Ir84a Ionotropic receptor 84a http://flybase.net/reports/FBgn0037501.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0036082=extracellular phenylacetaldehyde-gated ion channel activity, 0039706=co-receptor binding, 0004984=olfactory receptor activity, 0004970=ionotropic glutamate receptor activity" "0019226=transmission of nerve impulse, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0008049=male courtship behavior" "0043025=neuronal cell body, 0044292=dendrite terminus, 0016021=integral component of membrane, 0071683=sensory dendrite, 0043235=receptor complex, 0005887=integral component of plasma membrane" "DmelIR84a, ionotropic receptor 84a, IR84a, CT28433, CG10101" "IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor" CG10101 16-Dec-15 2015_12 "smell perception defective,recessive,neurophysiology defective,courtship behavior defective,male limited,viable,visible,body color defective" "trichogen cell,mesothoracic tergum,sensillum coeloconicum of antennal segment 3" FBgn0061139 l(3)S000627b lethal (3) S000627b http://flybase.net/reports/FBgn0061139.html gene 27-Jun 16-Dec-15 2015_12 lethal FBgn0005531 l(2)52ACh lethal (2) 52ACh http://flybase.net/reports/FBgn0005531.html gene unnamed 16-Dec-15 2015_12 FBgn0016805 l(1)K7 lethal (1) K7 http://flybase.net/reports/FBgn0016805.html gene K7 16-Dec-15 2015_12 "lethal,recessive" FBgn0065652 l(2)SH0732 lethal (2) SH0732 http://flybase.net/reports/FBgn0065652.html gene l(2)SH2 0732 16-Dec-15 2015_12 "lethal,recessive" FBgn0030800 Nprl2 Nitrogen permease regulator-like 2 http://flybase.net/reports/FBgn0030800.html protein_coding_gene "0005515=protein binding, 0016247=channel regulator activity" "0048813=dendrite morphogenesis, 0007293=germarium-derived egg chamber formation, 0015824=proline transport, 0038202=TORC1 signaling, 0034198=cellular response to amino acid starvation, 0048477=oogenesis, 0045792=negative regulation of cell size, 0015840=urea transport" "0005737=cytoplasm, 0035859=Seh1-associated complex, 0005634=nucleus, 0044754=autolysosome" "nprl2, npr2, CG9104, NPR2" IPR009348=Nitrogen permease regulator 2 CG9104 16-Dec-15 2015_12 ENSDARG00000059613(nprl2) YEL062W(NPR2) WBGene00018635(F49E8.1) ENSXETG00000000083(tusc4) ENSMUSG00000010057(Nprl2) ENSG00000114388(NPRL2) viable FBgn0027654 jdp jdp http://flybase.net/reports/FBgn0027654.html protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding "dJDP, p25a, JDP, CG2239" IPR001623=DnaJ domain CG2239 16-Dec-15 2015_12 ENSDARG00000042674 WBGene00010640(K07F5.16) ENSMUSG00000036764(Dnajc12) ENSG00000108176(DNAJC12) "viable,fertile" FBgn0003331 scg scrambled egg http://flybase.net/reports/FBgn0003331.html gene scrambled-egg 16-Dec-15 2015_12 FBgn0035964 Dhpr Dihydropteridine reductase http://flybase.net/reports/FBgn0035964.html protein_coding_gene "0004155=6,7-dihydropteridine reductase activity" 0008152=metabolic process "CG4665, DHPR" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain" CG4665 16-Dec-15 2015_12 "ENSDARG00000040190(qdpra),ENSDARG00000037378(qdprb1),ENSDARG00000070071(qdprb2)" WBGene00011398(qdpr-1) ENSXETG00000020341(Q5HZU9_XENTR) ENSMUSG00000015806(Qdpr) ENSG00000151552(QDPR) adult stage adult head

FBgn0051969 CR31969 http://flybase.net/reports/FBgn0051969.html FBgn0063125 non_protein_coding_gene BcDNA:LP03459 16-Dec-15 2015_12 FBgn0016857 l(1)N4 lethal (1) N4 http://flybase.net/reports/FBgn0016857.html gene N4 16-Dec-15 2015_12 "lethal,recessive" FBgn0053237 Ste:CG33237 Ste:CG33237 http://flybase.net/reports/FBgn0053237.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG33237, CG32605" "IPR000704=Casein kinase II, regulatory subunit, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG33237 16-Dec-15 2015_12 FBgn0040610 CG14263 http://flybase.net/reports/FBgn0040610.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003743 trb thread bristle http://flybase.net/reports/FBgn0003743.html gene 16-Dec-15 2015_12 "female sterile,male fertile,viable,male,visible,body color defective" "macrochaeta,microchaeta,wing,wing vein,trident" FBgn0015793 Rab19 Rab19 http://flybase.net/reports/FBgn0015793.html protein_coding_gene "0005096=GTPase activator activity, 0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding" "0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction, 0015031=protein transport" "0031982=vesicle, 0043025=neuronal cell body, 0005794=Golgi apparatus, 0055037=recycling endosome, 0045202=synapse" "Rab19, rab-related protein 3, rab19, Rab19s, Rab19/RP3, CG7062, O18339, DmRab19, Rab-related protein 3, Rab-r3, DRabRP3, AAF50452, Rab-RP3, DRABR3" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG7062 16-Dec-15 2015_12 ENSDARG00000059404(zgc:153788) WBGene00004278(rab-19) ENSXETG00000002673(TNeu042f01.1) ENSMUSG00000030055(Rab43) "ENSG00000172780(RAB43),ENSG00000185051" viable FBgn0262535 CG43089 http://flybase.net/reports/FBgn0262535.html protein_coding_gene 0006511=ubiquitin-dependent protein catabolic process lincRNA.427 "IPR011333=POZ domain, IPR016072=SKP1 component, dimerisation, IPR016073=SKP1 component, POZ domain" CG43089 16-Dec-15 2015_12 FBgn0065607 l(2)SH0843 lethal (2) SH0843 http://flybase.net/reports/FBgn0065607.html gene l(2)SH2 0843 16-Dec-15 2015_12 "lethal,recessive" FBgn0038582 CG7988 http://flybase.net/reports/FBgn0038582.html protein_coding_gene 0007623=circadian rhythm "IPR012942=Sensitivity To Red Light Reduced-like, SRR1" CG7988 16-Dec-15 2015_12 ENSDARG00000059028(zgc:153763) ENSMUSG00000029346(Srrd) ENSG00000100104(SRRD) viable FBgn0058315 CG40315 http://flybase.net/reports/FBgn0058315.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028585 l(3)rI165 lethal (3) rI165 http://flybase.net/reports/FBgn0028585.html gene "lethal (?) rI165, unnamed, l(?)rI165" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051451 CR31451 http://flybase.net/reports/FBgn0051451.html "FBgn0027701, FBgn0063242" non_protein_coding_gene "gh16531, CG31451, anon-EST:Posey277, BcDNA:GH16531" CR31451 16-Dec-15 2015_12 FBgn0054012 CG34012 http://flybase.net/reports/FBgn0054012.html FBgn0082892 protein_coding_gene "unnamed, BP1014" CG34012 16-Dec-15 2015_12 FBgn0060363 l(3)S138613a lethal (3) S138613a http://flybase.net/reports/FBgn0060363.html gene 1386/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0022772 Orc1 Origin recognition complex subunit 1 http://flybase.net/reports/FBgn0022772.html protein_coding_gene "0005524=ATP binding, 0003677=DNA binding, 0003682=chromatin binding" "0022008=neurogenesis, 0006277=DNA amplification, 0006342=chromatin silencing, 0006270=DNA replication initiation, 0006261=DNA-dependent DNA replication, 0008283=cell proliferation, 0042023=DNA endoreduplication" "0005664=nuclear origin of replication recognition complex, 0005634=nucleus" "dORC1, DmOrc1p, orc1, DmOrc1, ORC, CG10667, ORC1, origin recognition complex 1, DmORC1, rDmORC" "IPR001025=Bromo adjacent homology (BAH) domain, IPR015163=Cdc6, C-terminal domain, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003593=AAA+ ATPase domain" CG10667 16-Dec-15 2015_12 ENSDARG00000039217(orc1l) "YLR442C(SIR3),YML065W(ORC1)" ENSXETG00000008059(orc1l) ENSMUSG00000028587(Orc1l) ENSG00000085840(ORC1) embryonic stage && larval stage "lethal,polyphasic,female sterile,male sterile,visible,neuroanatomy defective,viable" "eye,ommatidium,interommatidial bristle,eye-antennal disc,posterior,morphogenetic furrow,stage S10B oocyte,follicle cell & nucleus,egg,chorion,dorsal appendage,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC07496 K -1.173812525 -0.393555002 -0.644168193 -1.49636062 0.220241507 1.822720547 FBgn0082339 HM617 HM617 http://flybase.net/reports/FBgn0082339.html gene 16-Dec-15 2015_12 FBgn0082980 snoRNA:ë¬28S-2996 snoRNA:ë¬28S-2996 http://flybase.net/reports/FBgn0082980.html snoRNA_gene "psi28s-2996, snoRNA:Psi28S-2996, snoRNA:RpL5-a, Psi 28S-2996" CR43565 16-Dec-15 2015_12 FBgn0084040 CG41480 http://flybase.net/reports/FBgn0084040.html FBan0041480 protein_coding_gene 16-Dec-15 2015_12 FBgn0014287 l(3)64Af lethal (3) 64Af http://flybase.net/reports/FBgn0014287.html gene 16-Dec-15 2015_12 FBgn0004564 l(3)63Bh lethal (3) 63Bh http://flybase.net/reports/FBgn0004564.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065312 l(2)SH1938 lethal (2) SH1938 http://flybase.net/reports/FBgn0065312.html gene l(2)SH2 1938 16-Dec-15 2015_12 "lethal,recessive" FBgn0035384 CG2113 http://flybase.net/reports/FBgn0035384.html FBgn0063320 protein_coding_gene BcDNA:AT18037 IPR027817=Costars domain CG2113 16-Dec-15 2015_12 FBgn0267660 CR45998 http://flybase.net/reports/FBgn0267660.html non_protein_coding_gene CR45998 16-Dec-15 2015_12 FBgn0265889 CR44678 http://flybase.net/reports/FBgn0265889.html non_protein_coding_gene CR44678 16-Dec-15 2015_12 FBgn0066314 Aexon.s Aexon.s http://flybase.net/reports/FBgn0066314.html gene Aexon s 16-Dec-15 2015_12 FBgn0015372 RabX1 RabX1 http://flybase.net/reports/FBgn0015372.html FBgn0034872 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0016192=vesicle-mediated transport, 0007422=peripheral nervous system development, 0015031=protein transport, 0032482=Rab protein signal transduction" "0045202=synapse, 0005886=plasma membrane, 0055037=recycling endosome, 0031982=vesicle" "chrowded, l(2)k06908, chr, rabX1, CG3870, Chrw, RabX1, AAF47018, RAB5c, chrw, DmRabX1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type" CG3870 16-Dec-15 2015_12 "lethal,recessive" "chordotonal organ,lateral,ventral,external sensory organ,multidendritic neuron" FBgn0060635 l(3)S084512b lethal (3) S084512b http://flybase.net/reports/FBgn0060635.html gene 0845/12 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0036931 CG14183 http://flybase.net/reports/FBgn0036931.html protein_coding_gene 0005524=ATP binding "IPR000048=IQ motif, EF-hand binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG14183 16-Dec-15 2015_12 viable FBgn0011216 disd dispersed http://flybase.net/reports/FBgn0011216.html gene 0007286=spermatid development 16-Dec-15 2015_12 male semi-sterile spermatid & nucleus FBgn0015499 l(3)65CEc lethal (3) 65CEc http://flybase.net/reports/FBgn0015499.html gene "Distal W5.4 Group XII, XII" 16-Dec-15 2015_12 lethal FBgn0065920 l(2)SH0155 lethal (2) SH0155 http://flybase.net/reports/FBgn0065920.html gene l(2)SH2 0155 16-Dec-15 2015_12 "lethal,recessive" FBgn0267576 CR45916 http://flybase.net/reports/FBgn0267576.html non_protein_coding_gene pri-mir-9a CR45916 16-Dec-15 2015_12 FBgn0015894 su(Ubxbx-1) su(Ubxbx-1) http://flybase.net/reports/FBgn0015894.html gene "unnamed, anon-85AB" 16-Dec-15 2015_12 FBgn0051681 CG31681 http://flybase.net/reports/FBgn0051681.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG31681 16-Dec-15 2015_12 viable FBgn0005744 l(1)TK236 lethal (1) TK236 http://flybase.net/reports/FBgn0005744.html gene l236 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0259192 CG42296 http://flybase.net/reports/FBgn0259192.html "FBgn0040105, FBgn0031385" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG15378 IPR002557=Chitin binding domain CG42296 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC00394 E -0.0177916 0.429054985 0.236141796 1.634882326 0.239216821 -0.30082429 FBgn0031463 G6P Glucose-6-Phosphatase http://flybase.net/reports/FBgn0031463.html protein_coding_gene 0004346=glucose-6-phosphatase activity 0016020=membrane "CG15400, G6pase, glucose-6-phosphatase" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG15400 16-Dec-15 2015_12 "ENSDARG00000013721(si:ch211-215l11.5),ENSDARG00000014967(g6pcb),ENSDARG00000031616(g6pca),ENSDARG00000020371(zgc:158425)" "ENSXETG00000024588(g6pc),ENSXETG00000012583(),ENSXETG00000013641()" "ENSMUSG00000078650(G6pc),ENSMUSG00000005232(G6pc2),ENSMUSG00000034793(G6pc3)" "ENSG00000152254(G6PC2),ENSG00000131482(G6PC),ENSG00000141349(G6PC3)" viable FBgn0015997 l(3)100CDa lethal (3) 100CDa http://flybase.net/reports/FBgn0015997.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052247 CG32247 http://flybase.net/reports/FBgn0052247.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038262 CG14857 http://flybase.net/reports/FBgn0038262.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG14857 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" FBgn0267987 CR46254 http://flybase.net/reports/FBgn0267987.html non_protein_coding_gene CR46254 16-Dec-15 2015_12 FBgn0261503 CR42651 http://flybase.net/reports/FBgn0261503.html non_protein_coding_gene "CG42651, pri-mir-10" CR42651 16-Dec-15 2015_12 FBgn0027216 l(1)G0329 lethal (1) G0329 http://flybase.net/reports/FBgn0027216.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001409 l(1)3Bd lethal (1) 3Bd http://flybase.net/reports/FBgn0001409.html gene "ZW-7, zw-7, l(1)zw7, zw7" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,germline clone,cell lethal,lethal - all die before end of P-stage,some die during pharate adult stage" "female reproductive system,egg,germline clone" FBgn0051874 CG31874 http://flybase.net/reports/FBgn0051874.html FBgn0045340 protein_coding_gene 0004333=fumarate hydratase activity "0006106=fumarate metabolic process, 0006099=tricarboxylic acid cycle" "0045239=tricarboxylic acid cycle enzyme complex, 0005739=mitochondrion" NEST:bs10e11 "IPR024083=Fumarase/histidase, N-terminal, IPR000362=Fumarate lyase family, IPR020557=Fumarate lyase, conserved site, IPR022761=Fumarate lyase, N-terminal, IPR005677=Fumarate hydratase, class II, IPR018951=Fumarase C, C-terminal, IPR008948=L-Aspartase-like" CG31874 16-Dec-15 2015_12 ENSDARG00000068620 ENSXETG00000006529(FH) viable FBgn0002250 l(3)68Eb lethal (3) 68Eb http://flybase.net/reports/FBgn0002250.html gene "rose-gespleten region interval 12, rsg12, l(3)rsg12" 16-Dec-15 2015_12 lethal FBgn0000956 fs(2)E3 female sterile (2) E3 http://flybase.net/reports/FBgn0000956.html gene fs2.3 16-Dec-15 2015_12 "female sterile,recessive,visible" "wing,female reproductive system" FBgn0036706 ND-24L NADH dehydrogenase (ubiquinone) 24 kDa subunit-like http://flybase.net/reports/FBgn0036706.html protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH-ubiquinone oxidoreductase 24 kDa subunit, CG6485, NUHM, NADH:ubiquinone oxidoreductase 24 kDa subunit" "IPR002023=NADH-quinone oxidoreductase subunit E-like, IPR012336=Thioredoxin-like fold" CG6485 16-Dec-15 2015_12 viable FBgn0028424 JhI-26 Juvenile hormone-inducible protein 26 http://flybase.net/reports/FBgn0028424.html FBgn0034108 protein_coding_gene 0045924=regulation of female receptivity "CG3767, unnamed" "IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227" CG3767 16-Dec-15 2015_12 viable FBgn0025168 l(2)38EFc lethal (2) 38EFc http://flybase.net/reports/FBgn0025168.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266325 CR44990 http://flybase.net/reports/FBgn0266325.html non_protein_coding_gene CR44990 16-Dec-15 2015_12 FBgn0002355 l(3)87Eb lethal (3) 87Eb http://flybase.net/reports/FBgn0002355.html gene "B16, B16-1, l(3)B16-1, l(3)B16" 16-Dec-15 2015_12 lethal FBgn0041629 Hexo2 Hexosaminidase 2 http://flybase.net/reports/FBgn0041629.html FBgn0030059 protein_coding_gene "0004563=beta-N-acetylhexosaminidase activity, 0016231=beta-N-acetylglucosaminidase activity" "0044130=negative regulation of growth of symbiont in host, 0005975=carbohydrate metabolic process, 0032504=multicellular organism reproduction" "0005886=plasma membrane, 0005615=extracellular space" "CG1787, hexosaminidase 2, DmHex2, HEX2, HEX 2, HEXO2" "IPR015883=Glycoside hydrolase family 20, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR029019=Beta-hexosaminidase, eukaryotic type, N-terminal, IPR025705=Beta-hexosaminidase, IPR029018=Chitobiase/beta-hexosaminidase domain 2-like, IPR013781=Glycoside hydrolase, catalytic domain" CG1787 16-Dec-15 2015_12 "ENSDARG00000034368(hexa),ENSDARG00000052113(zgc:112084)" WBGene00020509(hex-1) ENSXETG00000005075(HEXB) "ENSMUSG00000025232(Hexa),ENSMUSG00000021665(Hexb)" "ENSG00000213614(HEXA),ENSG00000049860(HEXB)" "viable,fertile" FBgn0032261 CG6094 http://flybase.net/reports/FBgn0032261.html protein_coding_gene 0003747=translation release factor activity 0006415=translational termination FBgn 32261 IPR000352=Peptide chain release factor class I/class II CG6094 16-Dec-15 2015_12 YOL114C() WBGene00019838(R02F2.9) ENSXETG00000012505(ICT1) ENSMUSG00000018858(Ict1) ENSG00000167862(ICT1) "viable,visible" trichogen cell FBgn0027153 l(3)61Db lethal (3) 61Db http://flybase.net/reports/FBgn0027153.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0000364 Cpt Clipt http://flybase.net/reports/FBgn0000364.html gene CPTI 16-Dec-15 2015_12 "male sterile,lethal,recessive" macrochaeta FBgn0086350 tef teflon http://flybase.net/reports/FBgn0086350.html "FBgn0043472, FBgn0021831, FBgn0034185" protein_coding_gene 0046872=metal ion binding "0007060=male meiosis chromosome segregation, 0007141=male meiosis I, 0007129=synapsis" "l(2)k15914, CG8961, Teflon, teflon, lethal (2) k15914" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG8961 16-Dec-15 2015_12 FBgn0028285 l(1)G0411 lethal (1) G0411 http://flybase.net/reports/FBgn0028285.html gene 16-Dec-15 2015_12 "partially lethal - majority die,male,female,recessive" FBgn0265559 21.28 http://flybase.net/reports/FBgn0265559.html gene 16-Dec-15 2015_12 learning defective FBgn0011602 IM137 IM137 http://flybase.net/reports/FBgn0011602.html gene 16-Dec-15 2015_12 FBgn0005115 l(1)2269 lethal (1) 2269 http://flybase.net/reports/FBgn0005115.html gene 16-Dec-15 2015_12 "lethal,tumorigenic" imaginal disc FBgn0004651 Fs(2)M Female sterile of Meyer http://flybase.net/reports/FBgn0004651.html "FBgn0000929, FBgn0000995" gene "Fs(2)D-M, Fs" 16-Dec-15 2015_12 "female sterile,dominant,male fertile,visible" FBgn0000657 fin finer http://flybase.net/reports/FBgn0000657.html gene 16-Dec-15 2015_12 "visible,male sterile,viable,male" macrochaeta FBgn0040571 CG17193 http://flybase.net/reports/FBgn0040571.html FBgn0063675 protein_coding_gene BcDNA:RE41733 CG17193 16-Dec-15 2015_12 viable FBgn0033794 CG13326 http://flybase.net/reports/FBgn0033794.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG13326 16-Dec-15 2015_12 ENSMUSG00000037683(Armc3) ENSG00000165309(ARMC3) viable FBgn0043532 Obp56i Odorant-binding protein 56i http://flybase.net/reports/FBgn0043532.html "FBgn0050448, FBgn0063480" protein_coding_gene 0005549=odorant binding "0032504=multicellular organism reproduction, 0007606=sensory perception of chemical stimulus" "0005576=extracellular region, 0005615=extracellular space" "unnamed, CG30448, 56i, DmelObp56i, Obp-a, anon-AE003794.2, 56I" IPR006170=Pheromone/general odorant binding protein CG30448 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0051925 CG31925 http://flybase.net/reports/FBgn0051925.html protein_coding_gene 16-Dec-15 2015_12 FBgn0082924 snoRNA:Or-aca2 snoRNA:Or-aca2 http://flybase.net/reports/FBgn0082924.html snoRNA_gene "Or_aca2 snoRNA, DmOr_aca2 snoRNA, CR34593, Or-aca2, DmOr_aca2" CR34593 16-Dec-15 2015_12 FBgn0032601 yellow-b yellow-b http://flybase.net/reports/FBgn0032601.html protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "CG17914, Yellow-b, yell-b" "IPR017996=Major royal jelly protein/Protein yellow, IPR011042=Six-bladed beta-propeller, TolB-like" CG17914 16-Dec-15 2015_12 " embryonic stage , pupal stage , adult stage , larval stage " adult head

viable FBgn0069088 rpr::hid rpr::W http://flybase.net/reports/FBgn0069088.html engineered_fusion_gene rpr::W 16-Dec-15 2015_12 increased cell death FBgn0267572 CR45912 http://flybase.net/reports/FBgn0267572.html non_protein_coding_gene CR45912 16-Dec-15 2015_12 FBgn0010932 l(3)09070 lethal (3) 09070 http://flybase.net/reports/FBgn0010932.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0030087 CG7766 http://flybase.net/reports/FBgn0030087.html protein_coding_gene "0005516=calmodulin binding, 0003824=catalytic activity, 0008607=phosphorylase kinase regulator activity" 0005977=glycogen metabolic process 0005964=phosphorylase kinase complex "IPR008734=Phosphorylase kinase alpha/beta subunit, IPR012341=Six-hairpin glycosidase, IPR008928=Six-hairpin glycosidase-like, IPR011613=Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family" CG7766 16-Dec-15 2015_12 "ENSDARG00000059681(phka1),ENSDARG00000030749(LOC562402),ENSDARG00000030687(LOC556199)" WBGene00015754(C14B9.8) "ENSXETG00000006756(PHKA2),ENSXETG00000018114()" "ENSMUSG00000034055(Phka1),ENSMUSG00000031295(Phka2)" "ENSG00000044446(PHKA2),ENSG00000067177(PHKA1)" FBgn0032415 rho-6 rhomboid-6 http://flybase.net/reports/FBgn0032415.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0016021=integral component of membrane "Rho-related [33C1], rho6, Rhomboid-6, rho 6, CG17212" "IPR002610=Peptidase S54, rhomboid, IPR017213=Peptidase S54, rhomboid, metazoan, IPR022764=Peptidase S54, rhomboid domain" CG17212 16-Dec-15 2015_12 viable FBgn0043994 Su(rst)D207 Su(rst)D207 http://flybase.net/reports/FBgn0043994.html gene 0001745=compound eye morphogenesis D207 16-Dec-15 2015_12 viable FBgn0266966 CR45417 http://flybase.net/reports/FBgn0266966.html non_protein_coding_gene CR45417 16-Dec-15 2015_12 FBgn0005433 l(1)v3 lethal (1) v3 http://flybase.net/reports/FBgn0005433.html gene l(1)3 16-Dec-15 2015_12 FBgn0016942 stich2 sticky ch2 http://flybase.net/reports/FBgn0016942.html FBgn0011718 gene 0007422=peripheral nervous system development "sticky ch, sticky-chordotonals, sticky ch1-2" 16-Dec-15 2015_12 "lethal,recessive" chordotonal organ FBgn0259869 Su(Ste):CR42438 Su(Ste):CR42438 http://flybase.net/reports/FBgn0259869.html non_protein_coding_gene CR42438 CR42438 16-Dec-15 2015_12 FBgn0002616 M(3)69E Minute (3) 69E http://flybase.net/reports/FBgn0002616.html gene "M(3)y, M(3)33j, M(3)33d, Mh, M(3)6, M[33d30], M(3)h[y], M(3L)h, M(3)h, M(3)v" 16-Dec-15 2015_12 "Minute,dominant,visible,developmental rate defective,eye color defective" "macrochaeta,eye,wing,pigment cell,wing vein L2,posterior crossvein" FBgn0259406 C153 http://flybase.net/reports/FBgn0259406.html gene 16-Dec-15 2015_12 visible "wing,wing margin" FBgn0025747 l(3)95Az lethal (3) 95Az http://flybase.net/reports/FBgn0025747.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000969 fs(2)eo5 female sterile (2) eo5 http://flybase.net/reports/FBgn0000969.html gene 0048477=oogenesis "fs(2)eoWP19, fs(2)eo-G, wp19" 16-Dec-15 2015_12 female sterile FBgn0083311 E(smoDN)1414 Enhancer of smoDN 1414 http://flybase.net/reports/FBgn0083311.html gene 16-Dec-15 2015_12 FBgn0002406 l(3)99Dg lethal (3) 99Dg http://flybase.net/reports/FBgn0002406.html gene 16-Dec-15 2015_12 lethal FBgn0060925 l(3)S042205 lethal (3) S042205 http://flybase.net/reports/FBgn0060925.html gene 0422/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060522 l(3)S102312b lethal (3) S102312b http://flybase.net/reports/FBgn0060522.html gene 1023/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0061497 l(2)45Ap lethal (2) 45Ap http://flybase.net/reports/FBgn0061497.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266171 pre-mod(mdg4)-AB http://flybase.net/reports/FBgn0266171.html protein_coding_gene CG44877 "IPR007588=Zinc finger, FLYWCH-type" CG44877 16-Dec-15 2015_12 FBgn0262765 Mst77Y-17ë¬ Male-specific pseudogene 77Y 17 http://flybase.net/reports/FBgn0262765.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0020811 mei-1223 mei-1223 http://flybase.net/reports/FBgn0020811.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" spermatid FBgn0266693 CR45183 http://flybase.net/reports/FBgn0266693.html non_protein_coding_gene CR45183 16-Dec-15 2015_12 FBgn0001833 l(1)ts504 lethal (1) ts504 http://flybase.net/reports/FBgn0001833.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "adult head,adult thorax" FBgn0040588 CG13841 http://flybase.net/reports/FBgn0040588.html protein_coding_gene CG13841 16-Dec-15 2015_12 DRSC26257 K -0.710219897 -0.906539037 0.246235043 -0.343377375 -0.079942826 1.752175511 FBgn0265699 CR44506 http://flybase.net/reports/FBgn0265699.html non_protein_coding_gene CR44506 16-Dec-15 2015_12 FBgn0053491 CR33491 http://flybase.net/reports/FBgn0053491.html pseudogene_attribute CG33491 CR33491 16-Dec-15 2015_12 "ENSDARG00000053593(LOC100329372),ENSDARG00000013335(LOC100333447)" FBgn0263745 CR43670 http://flybase.net/reports/FBgn0263745.html "FBgn0051782, FBgn0062488" pseudogene_attribute "BcDNA:GM06363, CG31782" CR43670 16-Dec-15 2015_12 viable FBgn0264325 Atg6 Autophagy-related 6 http://flybase.net/reports/FBgn0264325.html "FBgn0010709, FBgn0039144, FBgn0086211" protein_coding_gene "0048102=autophagic cell death, 1902350=cellular response to chloroquine, 0016322=neuron remodeling, 0035096=larval midgut cell programmed cell death, 0050829=defense response to Gram-negative bacterium, 0009306=protein secretion, 0035071=salivary gland cell autophagic cell death, 0006979=response to oxidative stress, 0030097=hemopoiesis, 0045824=negative regulation of innate immune response, 0006914=autophagy, 0006897=endocytosis" "0034271=phosphatidylinositol 3-kinase complex, class III, type I" "Beclin1, ATG6, beclin, Autophagy-specific gene 6, atg6, Beclin-1, beclin 1, CG5429, l(3)00096, DmAtg6" IPR007243=Atg6/Beclin CG5429 16-Dec-15 2015_12 YPL120W(VPS30) WBGene00000247(bec-1) ENSXETG00000012613(Q4A1L3_XENTR) ENSMUSG00000035086(Becn1) ENSG00000126581(BECN1) FBgn0026141 Cdlc2 Cytoplasmic dynein light chain 2 http://flybase.net/reports/FBgn0026141.html FBgn0044766 protein_coding_gene "0042623=ATPase activity, coupled, 0003774=motor activity" "0007017=microtubule-based process, 0007018=microtubule-based movement" "0005737=cytoplasm, 0005856=cytoskeleton, 0030286=dynein complex, 0005868=cytoplasmic dynein complex" "dynein, CG5450, cytoplasmic dynein, Cytoplasmic dynein, Cyto dynein light chain 2, anon-WO0140519.117, 8kd dynein light chain, dlc, Cdcl2" "IPR019763=Dynein light chain, type 1/2, conserved site, IPR001372=Dynein light chain, type 1/2" CG5450 16-Dec-15 2015_12 ENSDARG00000058454(dynll1) YDR424C(DYN2) WBGene00001005(dlc-1) ENSXETG00000007996(dlc2) ENSMUSG00000020483(Dynll2) ENSG00000121083(DYNLL2) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0034128 CG4409 http://flybase.net/reports/FBgn0034128.html protein_coding_gene IPR010629=Insect allergen-related CG4409 16-Dec-15 2015_12 viable FBgn0001766 l(1)M26 lethal (1) M26 http://flybase.net/reports/FBgn0001766.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029724 CG15472 http://flybase.net/reports/FBgn0029724.html protein_coding_gene CG15472 16-Dec-15 2015_12 viable FBgn0030136 RpS28b Ribosomal protein S28b http://flybase.net/reports/FBgn0030136.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0002181=cytoplasmic translation, 0006407=rRNA export from nucleus" 0022627=cytosolic small ribosomal subunit "CG2998, RS28_DROME" "IPR000289=Ribosomal protein S28e, IPR028626=Ribosomal protein S28e conserved site, IPR012340=Nucleic acid-binding, OB-fold" CG2998 16-Dec-15 2015_12 ENSDARG00000035860(rps28) "YLR264W(RPS28B),YOR167C(RPS28A)" WBGene00004497(rps-28) ENSXETG00000021905() "ENSMUSG00000067288(Rps28),ENSMUSG00000069188(Gm13192),ENSMUSG00000069196(Gm10263),ENSMUSG00000072576(Gm16417),ENSMUSG00000066407(Gm10161)" lethal DRSC18258 EK -0.142827143 -1.045384294 0.280846002 -1.758446591 1.554184109 3.1699096 FBgn0267493 Mst77Y-9 Male-specific transcript 77Y 9 http://flybase.net/reports/FBgn0267493.html "FBgn0262758, FBgn0267416" protein_coding_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin CG45769 CG45769 16-Dec-15 2015_12 FBgn0021433 Dl::Ser Dl::Ser http://flybase.net/reports/FBgn0021433.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "macrochaeta & thorax | supernumerary-537.4,ommatidium & eye disch-H10,photoreceptor cell R8 & eye disch-H10,macrochaeta & thorax | supernumerary | somatic clone | cell autonomousUbx.PdC,eye" FBgn0028050 l(3)S096108 lethal (3) S096108 http://flybase.net/reports/FBgn0028050.html gene 0961/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0064171 l(3)201.51 lethal (3) 201.51 http://flybase.net/reports/FBgn0064171.html gene "0007301=female germline ring canal formation, 0007300=ovarian nurse cell to oocyte transport" 16-Dec-15 2015_12 lethal FBgn0003539 Str Stretched wings http://flybase.net/reports/FBgn0003539.html gene 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0016029 l(3)89El lethal (3) 89El http://flybase.net/reports/FBgn0016029.html gene l(3)M171 16-Dec-15 2015_12 "lethal,recessive" FBgn0263536 mir-4974 mir-4974 stem loop http://flybase.net/reports/FBgn0263536.html miRNA_gene "dme-mir-4974, CR43521" CR43521 16-Dec-15 2015_12 FBgn0263964 BG01976 http://flybase.net/reports/FBgn0263964.html gene 16-Dec-15 2015_12 "long lived,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0065752 l(2)SH0496 lethal (2) SH0496 http://flybase.net/reports/FBgn0065752.html gene l(2)SH2 0496 16-Dec-15 2015_12 "lethal,recessive" FBgn0052334 CG32334 http://flybase.net/reports/FBgn0052334.html protein_coding_gene 16-Dec-15 2015_12 lethal FBgn0035254 CG7974 http://flybase.net/reports/FBgn0035254.html protein_coding_gene 0005654=nucleoplasm IPR010756=Hepatocellular carcinoma-associated antigen 59 CG7974 16-Dec-15 2015_12 ENSDARG00000002220(zgc:103692) WBGene00011969(T23G11.4) ENSXETG00000012840(TGas024o14.1) ENSMUSG00000026851(BC005624) ENSG00000136819(C9orf78) viable FBgn0031939 CG13796 http://flybase.net/reports/FBgn0031939.html "FBgn0051904, FBgn0031938" protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity, 0015187=glycine transmembrane transporter activity" 0006836=neurotransmitter transport 0016021=integral component of membrane "CT42497, CG13796-PA, CG18590" IPR000175=Sodium:neurotransmitter symporter CG13796 16-Dec-15 2015_12 "viable,planar polarity defective" FBgn0022327 l(1)A27.2 lethal (1) A27.2 http://flybase.net/reports/FBgn0022327.html gene A27.2 16-Dec-15 2015_12 "lethal,recessive" FBgn0020339 anon-5Cc anon-5Cc http://flybase.net/reports/FBgn0020339.html gene unnamed 16-Dec-15 2015_12 FBgn0264713 CR43981 http://flybase.net/reports/FBgn0264713.html non_protein_coding_gene CR43981 16-Dec-15 2015_12 FBgn0082190 l(3)S006603 lethal (3) S006603 http://flybase.net/reports/FBgn0082190.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037664 CG8420 http://flybase.net/reports/FBgn0037664.html FBgn0044694 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space anon-WO0140519.182 CG8420 16-Dec-15 2015_12 lethal FBgn0035932 CG13308 http://flybase.net/reports/FBgn0035932.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13308 16-Dec-15 2015_12 viable FBgn0052761 tRNA:CR32761:ë¬ transfer RNA:CR32761:pseudogene http://flybase.net/reports/FBgn0052761.html FBgn0060254 pseudogene_attribute "tRNA:EPsi:CTC:AE002566, AE002566.trna3-GluCTC, chrX.trna3-GluCTC, CR32761" CR32761 16-Dec-15 2015_12 FBgn0010764 l(3)01949 lethal (3) 01949 http://flybase.net/reports/FBgn0010764.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0034179 CG6805 http://flybase.net/reports/FBgn0034179.html FBgn0041576 protein_coding_gene 0046030=inositol trisphosphate phosphatase activity "0016311=dephosphorylation, 0046856=phosphatidylinositol dephosphorylation" "CK01299, BEST:CK01299, IPP" "IPR005135=Endonuclease/exonuclease/phosphatase, IPR000300=Inositol polyphosphate-related phosphatase" CG6805 16-Dec-15 2015_12 YOL065C(INP54) WBGene00016802(C50C3.7) "ENSXETG00000022881(INPP5K),ENSXETG00000016154(INPP5J)" ENSMUSG00000006127(Inpp5k) ENSG00000132376(INPP5K) "viable,fertile" FBgn0033135 Tsp42En Tetraspanin 42En http://flybase.net/reports/FBgn0033135.html FBgn0064852 protein_coding_gene 0016021=integral component of membrane "tetraspanin 42E, BcDNA:RH02160, CG12839, Dm.Tsp42En" "IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin" CG12839 16-Dec-15 2015_12 viable FBgn0050022 CG30022 http://flybase.net/reports/FBgn0050022.html "FBgn0033632, FBgn0064874" protein_coding_gene "CG9026, BcDNA:RE56416" IPR001279=Metallo-beta-lactamase CG30022 16-Dec-15 2015_12 ENSDARG00000005713(zgc:85680) WBGene00007886(C33A12.7) ENSXETG00000025507(ethe1) ENSMUSG00000064254(Ethe1) ENSG00000105755(ETHE1) viable FBgn0086673 CG13272 http://flybase.net/reports/FBgn0086673.html "FBgn0032607, FBgn0053312" protein_coding_gene CG33312 CG13272 16-Dec-15 2015_12 FBgn0019778 l(1)31 lethal (1) 31 http://flybase.net/reports/FBgn0019778.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013238 E(var)2 E(var)2 http://flybase.net/reports/FBgn0013238.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0004205 l(3)84Ec lethal (3) 84Ec http://flybase.net/reports/FBgn0004205.html gene 16-Dec-15 2015_12 lethal FBgn0065786 l(2)SH0435 lethal (2) SH0435 http://flybase.net/reports/FBgn0065786.html gene l(2)SH2 0435 16-Dec-15 2015_12 "lethal,recessive" FBgn0051833 CG31833 http://flybase.net/reports/FBgn0051833.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085828 CR42195 http://flybase.net/reports/FBgn0085828.html FBan0042195 rRNA_gene CR42195 16-Dec-15 2015_12 FBgn0011534 l(3)00707 lethal (3) 00707 http://flybase.net/reports/FBgn0011534.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005072 fs(2)OW213 female sterile (2) OW213 http://flybase.net/reports/FBgn0005072.html gene 16-Dec-15 2015_12 FBgn0030215 CG15296 http://flybase.net/reports/FBgn0030215.html FBgn0047327 protein_coding_gene BcDNA:AT26906 CG15296 16-Dec-15 2015_12 "fertile,viable" FBgn0034275 CG5002 http://flybase.net/reports/FBgn0034275.html protein_coding_gene "0015381=high-affinity sulfate transmembrane transporter activity, 0005215=transporter activity" "0055085=transmembrane transport, 0008272=sulfate transport" 0016021=integral component of membrane "IPR011547=SLC26A/SulP transporter domain, IPR002645=STAS domain, IPR001902=SLC26A/SulP transporter" CG5002 16-Dec-15 2015_12 ENSDARG00000043021(slc26a11) "YLR092W(SUL2),YBR294W(SUL1)" ENSMUSG00000039908(Slc26a11) ENSG00000181045(SLC26A11) viable FBgn0016660 H15 H15 http://flybase.net/reports/FBgn0016660.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0035050=embryonic heart tube development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035223=leg disc pattern formation, 0003015=heart process, 0007507=heart development, 0030381=chorion-containing eggshell pattern formation, 0022008=neurogenesis, 0042659=regulation of cell fate specification, 0042684=cardioblast cell fate commitment" 0005634=nucleus "Dm-H15, neuromancer 1, neuromancer-1, Nmr-1, nmr[H15], neuromancer1, dm-H15, Neuromancer, neuromancer, nmr1, neuromancer 2, Tbx20, CG6604, nmr, Nmr" "IPR002070=Transcription factor, Brachyury, IPR008967=p53-like transcription factor, DNA-binding, IPR018186=Transcription factor, T-box, conserved site, IPR001699=Transcription factor, T-box" CG6604 16-Dec-15 2015_12 ENSMUSG00000031965(Tbx20) ENSG00000164532(TBX20) "viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,somatic clone,embryonic/larval neuroblast,ganglion mother cell" FBgn0021944 Coprox Coproporphyrinogen oxidase http://flybase.net/reports/FBgn0021944.html "FBgn0021932, FBgn0027909" protein_coding_gene "0042803=protein homodimerization activity, 0004109=coproporphyrinogen oxidase activity" "0006783=heme biosynthetic process, 0055114=oxidation-reduction process" 0005739=mitochondrion "CG3433, Corpoporphyrinogen III oxidase, l(2)k10617, l(2)k11018, BcDNA:GM14838" "IPR018375=Coproporphyrinogen III oxidase, conserved site, IPR001260=Coproporphyrinogen III oxidase, aerobic" CG3433 16-Dec-15 2015_12 ENSDARG00000062025(cpox) YDR044W(HEM13) ENSXETG00000002047(CPOX) ENSMUSG00000022742(Cpox) ENSG00000080819(CPOX) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective" FBgn0039128 CG13599 http://flybase.net/reports/FBgn0039128.html protein_coding_gene 0007096=regulation of exit from mitosis 0005634=nucleus IPR009511=Mad1/Cdc20-bound-Mad2 binding protein CG13599 16-Dec-15 2015_12 ENSMUSG00000034509(Mad2l1bp) "viable,fertile,visible" trichogen cell FBgn0032221 CG5375 http://flybase.net/reports/FBgn0032221.html protein_coding_gene IPR015649=Schwannomin interacting protein 1 CG5375 16-Dec-15 2015_12 ENSMUSG00000027777(Schip1) ENSG00000151967(SCHIP1) viable FBgn0040589 CG13839 http://flybase.net/reports/FBgn0040589.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029054 l(1)G0453 lethal (1) G0453 http://flybase.net/reports/FBgn0029054.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0012027 tRNA:Y1:85Ad transfer RNA:tyr1:85Ad http://flybase.net/reports/FBgn0012027.html "FBgn0003849, FBgn0012014, FBgn0051552, FBgn0060002" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002708.trna60-TyrGTA, 85Ad, chr3R.trna66-TyrGTA, tRNA-Tyr, tRNA:tyr1:85Ad, tRNA[Tyr], tRNA:Y:GTA:AE002708-d, tRNA:Y, tRNA[Tyr][[1gamma]], Tyr-tRNA, CR31552" CR31552 16-Dec-15 2015_12 FBgn0069299 ali alice http://flybase.net/reports/FBgn0069299.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "filzkorper,ectopic,germline clone,maternal effect" FBgn0043588 EK3-3 EK3-3 http://flybase.net/reports/FBgn0043588.html gene "0007476=imaginal disc-derived wing morphogenesis, 0001745=compound eye morphogenesis" 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "eye,wing vein" FBgn0267593 CR45931 http://flybase.net/reports/FBgn0267593.html pseudogene_attribute CG40245 CR45931 16-Dec-15 2015_12 FBgn0044446 EP851 EP851 http://flybase.net/reports/FBgn0044446.html gene 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0031771 ND-51 NADH dehydrogenase (ubiquinone) 51 kDa subunit http://flybase.net/reports/FBgn0031771.html protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity, 0051539=4 iron, 4 sulfur cluster binding, 0051287=NAD binding, 0010181=FMN binding" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH ubiquinone oxidoreductase 51 kDa, NADH:ubiquinone oxidoreductase 51 kDa subunit, ND51, ubiquinone, NADH-UBIQUINONE OXIDOREDUCTASE 51 KDA SUBUNIT, NADH dehydrogenase, CG9140, NUBM, FBpp0078847, NADH:ubiquinone oxidoreductase, 51kDa subunit" "IPR019554=Soluble ligand binding domain, IPR011537=NADH ubiquinone oxidoreductase, F subunit, IPR019575=NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain, IPR001949=NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site, IPR011538=NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain" CG9140 16-Dec-15 2015_12 ENSDARG00000036438(ndufv1) WBGene00003831(nuo-1) ENSXETG00000003396(ndufv1) ENSMUSG00000037916(Ndufv1) ENSG00000167792(NDUFV1) "lethal,RU486 conditional,developmental rate defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266096 CR44833 http://flybase.net/reports/FBgn0266096.html non_protein_coding_gene Mgn94020 CR44833 16-Dec-15 2015_12 FBgn0086266 Vm26Ac Vitelline membrane 26Aac http://flybase.net/reports/FBgn0086266.html "FBgn0000647, FBgn0031754" protein_coding_gene 0008316=structural constituent of vitelline membrane 0007305=vitelline membrane formation involved in chorion-containing eggshell formation "0042600=chorion, 0035805=egg coat" "CG13997, fc 20, Fcp26Ac, fc20, Follicle cell protein 26Ac, TU-3, VM26Ac" IPR013135=Vitelline membrane cysteine-rich domain CG13997 16-Dec-15 2015_12 oogenesis stage | stage S8-11 FBgn0266795 CR45257 http://flybase.net/reports/FBgn0266795.html non_protein_coding_gene CR45257 16-Dec-15 2015_12 FBgn0259426 EP-1152.1 http://flybase.net/reports/FBgn0259426.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0085739 CR40507 http://flybase.net/reports/FBgn0085739.html FBan0040507 rRNA_gene CR40507 16-Dec-15 2015_12 FBgn0044082 E(rst)H253 E(rst)H253 http://flybase.net/reports/FBgn0044082.html gene 0001745=compound eye morphogenesis H253 16-Dec-15 2015_12 FBgn0039023 CG4723 http://flybase.net/reports/FBgn0039023.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain" CG4723 16-Dec-15 2015_12 viable FBgn0051603 tRNA:CR31603 transfer RNA:CR31603 http://flybase.net/reports/FBgn0051603.html FBgn0011843 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:D2:29E, CR31603, transfer RNA:asp2:29E, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna13-AspGTC, tRNA:asp2:29E" CR31603 16-Dec-15 2015_12 FBgn0052115 CG32115 http://flybase.net/reports/FBgn0052115.html FBgn0064884 protein_coding_gene BcDNA:RE40923 CG32115 16-Dec-15 2015_12 viable FBgn0063644 CE3-2 "Calcineurin enhancer, chromosome 3, group 2" http://flybase.net/reports/FBgn0063644.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002374 l(3)91Ff lethal (3) 91Ff http://flybase.net/reports/FBgn0002374.html gene "l(3)BE90, l(3)BE91" 16-Dec-15 2015_12 lethal FBgn0027085 Aats-leu Leucyl-tRNA synthetase http://flybase.net/reports/FBgn0027085.html FBgn0035576 protein_coding_gene "0004823=leucine-tRNA ligase activity, 0002161=aminoacyl-tRNA editing activity, 0005524=ATP binding" 0006429=leucyl-tRNA aminoacylation "0005739=mitochondrion, 0005759=mitochondrial matrix" "LeuRS, LRS, CG7479" "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR002302=Leucine-tRNA ligase, IPR013155=Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR009008=Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR015413=Methionyl/Leucyl tRNA synthetase, IPR002300=Aminoacyl-tRNA synthetase, class Ia" CG7479 16-Dec-15 2015_12 YLR382C(NAM2) WBGene00003074(lars-2) ENSXETG00000014411(LARS2) ENSMUSG00000035202(Lars2) ENSG00000011376(LARS2) embryonic stage

ubiquitous "viable,visible,decreased cell size,cell autonomous,somatic clone" "trichogen cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0266198 CR44893 http://flybase.net/reports/FBgn0266198.html non_protein_coding_gene lincRNA.1004 CR44893 16-Dec-15 2015_12 FBgn0001327 ks-1 male fertility factor ks1 http://flybase.net/reports/FBgn0001327.html gene Sms1 16-Dec-15 2015_12 male sterile FBgn0023470 anon-30Fd anon-30Fd http://flybase.net/reports/FBgn0023470.html gene 16-Dec-15 2015_12 FBgn0085520 CR40801 http://flybase.net/reports/FBgn0085520.html FBan0040801 pseudogene_attribute 0004639=phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 0006164=purine nucleotide biosynthetic process "CG40801, ade5-related" "IPR018236=SAICAR synthetase, conserved site, IPR028923=SAICAR synthetase/ADE2, N-terminal" CR40801 16-Dec-15 2015_12 FBgn0010926 l(3)07882 lethal (3) 07882 http://flybase.net/reports/FBgn0010926.html FBgn0038517 protein_coding_gene 0030515=snoRNA binding "0006364=rRNA processing, 0042274=ribosomal small subunit biogenesis" "0032040=small-subunit processome, 0005730=nucleolus" CG5824 IPR007276=Nucleolar protein 14 CG5824 16-Dec-15 2015_12 ENSDARG00000033945 YDL148C(NOP14) WBGene00021660(Y48G1A.4) ENSMUSG00000036693(Nop14) ENSG00000087269(NOP14) "partially lethal - majority die,recessive,lethal" FBgn0050291 CG30291 http://flybase.net/reports/FBgn0050291.html FBgn0034571 protein_coding_gene 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity 0012505=endomembrane system CG3282 IPR008491=Protein of unknown function DUF773 CG30291 16-Dec-15 2015_12 ENSDARG00000045092(cdkrap3) WBGene00013765(Y113G7B.16) ENSXETG00000027359(cdk5rap3) ENSMUSG00000018669(Cdk5rap3) ENSG00000108465(CDK5RAP3) viable FBgn0002010 l(2)36Fc lethal (2) 36Fc http://flybase.net/reports/FBgn0002010.html gene "36Fc, Fc, l(2)E53" 16-Dec-15 2015_12 lethal FBgn0041158 dos::tor dos::tor http://flybase.net/reports/FBgn0041158.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0012300 Dfd::Ubx Dfd::Ubx http://flybase.net/reports/FBgn0012300.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" head FBgn0023432 l(2)55Ca lethal (2) 55Ca http://flybase.net/reports/FBgn0023432.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0046689 Takl1 Tak1-like 1 http://flybase.net/reports/FBgn0046689.html "FBgn0043537, FBgn0051421" protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding, 0004709=MAP kinase kinase kinase activity" 0006468=protein phosphorylation 0005737=cytoplasm "anon-AE003732.1, TAKL1, FBgn0046689, extra2, CG31421" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG31421 16-Dec-15 2015_12 ENSDARG00000044615(LOC405768) "WBGene00013643(Y105C5A.24),WBGene00003396(mom-4)" ENSXETG00000025849(RIPK3) viable FBgn0003421 sld slender http://flybase.net/reports/FBgn0003421.html gene 16-Dec-15 2015_12 "viable,female,poor,male,reduced,visible,male fertile,male sterile" "adult abdomen,eye,wing" FBgn0020317 anon-8F6 anon-8F6 http://flybase.net/reports/FBgn0020317.html gene 8F6 16-Dec-15 2015_12 FBgn0041336 Cyp6t2ë¬ Cyp6t2ë¬ http://flybase.net/reports/FBgn0041336.html FBgn0051621 pseudogene_attribute "CR31621, Cyp6t2p, 6t2p" CR31621 16-Dec-15 2015_12 FBgn0065576 l(2)SH0953 lethal (2) SH0953 http://flybase.net/reports/FBgn0065576.html gene l(2)SH2 0953 16-Dec-15 2015_12 "lethal,recessive" FBgn0263496 CR43485 http://flybase.net/reports/FBgn0263496.html non_protein_coding_gene CR43485 16-Dec-15 2015_12 FBgn0036319 Ent3 Equilibrative nucleoside transporter 3 http://flybase.net/reports/FBgn0036319.html protein_coding_gene "0005337=nucleoside transmembrane transporter activity, 0008504=monoamine transmembrane transporter activity, 0015395=nucleoside transmembrane transporter activity, down a concentration gradient" "0055085=transmembrane transport, 0015858=nucleoside transport" 0016021=integral component of membrane "CG11010, DmEnt3, ent3, DmENT3" "IPR020846=Major facilitator superfamily domain, IPR002259=Equilibrative nucleoside transporter, IPR030198=Equilibrative nucleoside transporter 4" CG11010 16-Dec-15 2015_12 ENSDARG00000059690(slc29a4) ENSMUSG00000050822(Slc29a4) "ENSG00000164638(SLC29A4),ENSG00000214668" viable FBgn0263124 Ubx::Zzzz\Ubx2 http://flybase.net/reports/FBgn0263124.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0084045 CG41485 http://flybase.net/reports/FBgn0084045.html FBan0041485 protein_coding_gene 16-Dec-15 2015_12 FBgn0005167 l(2)G562 lethal (2) G562 http://flybase.net/reports/FBgn0005167.html gene 16-Dec-15 2015_12 lethal FBgn0260933 rempA reduced mechanoreceptor potential A http://flybase.net/reports/FBgn0260933.html "FBgn0016923, FBgn0031262" protein_coding_gene "0007605=sensory perception of sound, 0042384=cilium assembly, 0035721=intraciliary retrograde transport, 0035058=nonmotile primary cilium assembly" 0031513=nonmotile primary cilium "reduced mechanoreceptor potentials A, reduced mechanoreceptor potentials, remp, CG11838, RempA, REMPA, Oseg3, OSEG, oseg3, Che-11, IFT140, OSEG3, CHE-11, IFT40" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain" CG11838 16-Dec-15 2015_12 ENSDARG00000031886 WBGene00000490(che-11) ENSMUSG00000024169(Ift140) ENSG00000187535(IFT140) FBgn0003587 Su(var)2-4 Suppressor of variegation 2-4 http://flybase.net/reports/FBgn0003587.html gene "Su(var)b[5401], Su-var(2)4, Su(var)b5401" 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0002667 mat(2)ea-D maternal effect early arrest D http://flybase.net/reports/FBgn0002667.html gene mat(2)earlyQD68 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0022248 l(2)k01302 lethal (2) k01302 http://flybase.net/reports/FBgn0022248.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034397 CG15082 http://flybase.net/reports/FBgn0034397.html protein_coding_gene CG15082 16-Dec-15 2015_12 viable FBgn0038376 Hmt-1 Heavy metal tolerance factor 1 http://flybase.net/reports/FBgn0038376.html protein_coding_gene "0015086=cadmium ion transmembrane transporter activity, 0005524=ATP binding, 0005215=transporter activity, 0015232=heme transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0070574=cadmium ion transmembrane transport, 0046686=response to cadmium ion, 0071585=detoxification of cadmium ion, 0015886=heme transport" "0043190=ATP-binding cassette (ABC) transporter complex, 0005774=vacuolar membrane, 0016021=integral component of membrane, 0005743=mitochondrial inner membrane" "hmt-1, EP(3)3387, heavy metal tolerance factor 1, CG4225" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR030255=ATP-binding cassette subfamily B member 6, IPR017871=ABC transporter, conserved site, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG4225 16-Dec-15 2015_12 ENSDARG00000063297(abcb6) WBGene00001815(hmt-1) ENSXETG00000013892(ABCB6) ENSMUSG00000026198(Abcb6) ENSG00000115657(ABCB6) "viable,fertile" FBgn0016697 Prosë±5 Proteasome ë±5 subunit http://flybase.net/reports/FBgn0016697.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0000502=proteasome complex, 0019773=proteasome core complex, alpha-subunit complex, 0005839=proteasome core complex" "ProsMA5, PSA5_DROME, alpha-subunit of 20S proteasome, Proteasome alpha subunit, CG10938, Prosalpha5, PRCZ, PSMA5, 154644_at, 20s proteasome, alpha5, prosMA5, alpha5_dm, Alpha-5, 20S proteasome, alpha-5" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR023332=Proteasome A-type subunit, IPR001353=Proteasome, subunit alpha/beta" CG10938 16-Dec-15 2015_12 ENSDARG00000003526(psma5) YGR253C(PUP2) WBGene00003926(pas-5) "ENSMUSG00000068749(Psma5),ENSMUSG00000050490(Gm8394)" ENSG00000143106(PSMA5) lethal DRSC07514 IEK -2.13486607 -3.202508628 -0.045359637 -1.782343105 1.965226568 1.665925402 FBgn0010056 JmE Ju myoE http://flybase.net/reports/FBgn0010056.html gene Jm E 16-Dec-15 2015_12 aging defective FBgn0042097 yeti-MBT yeti Malignant Brain Tumor http://flybase.net/reports/FBgn0042097.html gene 0007095=mitotic G2 DNA damage checkpoint "yeti, SWC5" 16-Dec-15 2015_12 polytene chromosome FBgn0004823 fs(2)ltoAPV63 female sterile (2) ltoAPV63 http://flybase.net/reports/FBgn0004823.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0010052 Jhe Juvenile hormone esterase http://flybase.net/reports/FBgn0010052.html FBgn0034077 protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0005515=protein binding, 0004453=juvenile-hormone esterase activity" "0048149=behavioral response to ethanol, 0060179=male mating behavior, 0006719=juvenile hormone catabolic process" 0005739=mitochondrion "jhe, juvenile hormone esterase, JH-esterase, JH esterase, jh esterase, DmJhe, CG8425, JH, JHE" "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR019826=Carboxylesterase type B, active site" CG8425 16-Dec-15 2015_12 "WBGene00015077(B0238.13),WBGene00016863(C52A10.2),WBGene00015067(B0238.1)" "viable,mating defective,male,recessive,hyperactive,conditional,chemical resistant" FBgn0034644 CG10082 http://flybase.net/reports/FBgn0034644.html FBgn0046449 protein_coding_gene "0000828=inositol hexakisphosphate kinase activity, 0008440=inositol-1,4,5-trisphosphate 3-kinase activity" "0046488=phosphatidylinositol metabolic process, 0006468=protein phosphorylation" 0005737=cytoplasm "anon-WO0172774.149, dmIP6K" IPR005522=Inositol polyphosphate kinase CG10082 16-Dec-15 2015_12 "ENSDARG00000008310(ip6k2),ENSDARG00000019613(zgc:92046)" YDR173C(ARG82) WBGene00009262(F30A10.3) "ENSXETG00000005955(IP6K1),ENSXETG00000009324(IP6K2)" "ENSMUSG00000024210(Ip6k3),ENSMUSG00000032594(Ip6k1),ENSMUSG00000032599(Ip6k2)" "ENSG00000161896(IP6K3),ENSG00000176095(IP6K1),ENSG00000068745(IP6K2)" "viable,partially lethal - majority die,recessive" DRSC04054 K 0.560440401 -0.962290212 -0.141540065 0.845679138 0.099701232 1.524920336 FBgn0031134 CG1314 http://flybase.net/reports/FBgn0031134.html FBgn0044617 protein_coding_gene anon-WO0140519.251 CG1314 16-Dec-15 2015_12 viable FBgn0259962 Sfp33A1 Seminal fluid protein 33A1 http://flybase.net/reports/FBgn0259962.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 33A1, CG42472" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42472 16-Dec-15 2015_12 FBgn0025768 l(3)89Ch lethal (3) 89Ch http://flybase.net/reports/FBgn0025768.html gene l(3)M2912 16-Dec-15 2015_12 "lethal,recessive" FBgn0034626 CG10795 http://flybase.net/reports/FBgn0034626.html protein_coding_gene LD27358 IPR007829=TM2 domain CG10795 16-Dec-15 2015_12 ENSDARG00000057042(tm2d1) WBGene00013446(Y66D12A.21) ENSMUSG00000028563(Tm2d1) ENSG00000162604(TM2D1) viable FBgn0262945 CR43264 http://flybase.net/reports/FBgn0262945.html non_protein_coding_gene CR43264 16-Dec-15 2015_12 FBgn0262467 Scox Synthesis of cytochrome c oxidase http://flybase.net/reports/FBgn0262467.html "FBgn0031656, FBgn0065353" protein_coding_gene "0016531=copper chaperone activity, 0004129=cytochrome-c oxidase activity" "0006825=copper ion transport, 0048477=oogenesis, 0007308=oocyte construction, 0008535=respiratory chain complex IV assembly, 0017004=cytochrome complex assembly, 0006878=cellular copper ion homeostasis, 0031987=locomotion involved in locomotory behavior, 0002168=instar larval development, 0060361=flight" "0005739=mitochondrion, 0005743=mitochondrial inner membrane" "Sco1 protein homolog, scox, dSco1, lethal (2) SH1783, SCOX, l(2)SH2 1783, SCO, SCO1, SCO1 protein homolog, CG8885, l(2)SH1783" "IPR003782=Copper chaperone SCO1/SenC, IPR017276=Synthesis of cytochrome c oxidase, Sco1/Sco2, IPR012336=Thioredoxin-like fold" CG8885 16-Dec-15 2015_12 ENSDARG00000067593 "YBR037C(SCO1),YBR024W(SCO2)" WBGene00015297(sco-1) ENSXETG00000025250(SCO1) ENSMUSG00000069844(Sco1) ENSG00000133028(SCO1) DRSC03117 E -0.431363088 -0.263998782 -1.668874892 0.021571532 0.408687422 -0.590105257 FBgn0086446 DCTN6-p27 "Dynactin 6, p27 subunit" http://flybase.net/reports/FBgn0086446.html "FBgn0002033, FBgn0032761" protein_coding_gene 0007018=microtubule-based movement 0005869=dynactin complex "l(2)37Ce)E62, Ce, CG17347, lethal (2) 37Ce, P27 DYNACTIN, dynactin, p27 subunit, l(2)E62, l(2)37Ce" "IPR001451=Hexapeptide repeat, IPR011004=Trimeric LpxA-like, IPR027777=Dynactin subunit 6" CG17347 16-Dec-15 2015_12 WBGene00021827(Y54E10A.5) ENSXETG00000010252(dctn6) ENSMUSG00000031516(Dctn6) ENSG00000104671(DCTN6) FBgn0004559 Su(var)308 Suppressor of variegation 308 http://flybase.net/reports/FBgn0004559.html gene 16-Dec-15 2015_12 FBgn0032730 CG10431 http://flybase.net/reports/FBgn0032730.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0008270=zinc ion binding" "0006351=transcription, DNA-templated, 0048813=dendrite morphogenesis" 0005634=nucleus dmCG10431 "IPR015880=Zinc finger, C2H2-like, IPR006612=Zinc finger, C2CH-type, IPR007087=Zinc finger, C2H2, IPR027775=C2H2- zinc finger protein family, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG10431 16-Dec-15 2015_12 "viable,neuroanatomy defective" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC" FBgn0085501 CG40609 http://flybase.net/reports/FBgn0085501.html FBan0040609 protein_coding_gene 16-Dec-15 2015_12 FBgn0040711 CG15409 http://flybase.net/reports/FBgn0040711.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005180 l(2)S3 lethal of Seto 3 http://flybase.net/reports/FBgn0005180.html gene 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" "puparium,prepupa,pupal tracheal system" FBgn0052421 tRNA:CR32421 transfer RNA:CR32421 http://flybase.net/reports/FBgn0052421.html "FBgn0011995, FBgn0011996, FBgn0060019" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033451=GUA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:V:TAC:AE002602-a, tRNA:val3a:64D, valine tRNA, tRNA[Val][[3a]], chr3L.trna46-ValTAC, CR32421, tRNA:V3a, tRNA:V3a:64D, transfer RNA:val3a:64D, AE002602.trna12-ValTAC" CR32421 16-Dec-15 2015_12 FBgn0061111 l(3)S006615 lethal (3) S006615 http://flybase.net/reports/FBgn0061111.html gene 0066/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052603 CG32603 http://flybase.net/reports/FBgn0052603.html protein_coding_gene IPR022727=Pupal cuticle protein C1 CG32603 16-Dec-15 2015_12 ENSXETG00000021007() DRSC21586 E 0.49237136 0.341005411 0.575960863 1.838739213 1.426685488 -0.521452156 FBgn0021822 l(2)k16207 lethal (2) k16207 http://flybase.net/reports/FBgn0021822.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065767 l(2)SH0471 lethal (2) SH0471 http://flybase.net/reports/FBgn0065767.html gene l(2)SH2 0471 16-Dec-15 2015_12 "lethal,recessive" FBgn0024878 l(2)52Fc lethal (2) 52Fc http://flybase.net/reports/FBgn0024878.html gene D8.13 16-Dec-15 2015_12 lethal FBgn0065232 l(2)SH2169 lethal (2) SH2169 http://flybase.net/reports/FBgn0065232.html gene l(2)SH2 2169 16-Dec-15 2015_12 "lethal,recessive" FBgn0033097 Zip42C.2 Zinc/iron regulated transporter-related protein 42C.2 http://flybase.net/reports/FBgn0033097.html protein_coding_gene 0005385=zinc ion transmembrane transporter activity 0071578=zinc II ion transmembrane import "0016323=basolateral plasma membrane, 0016324=apical plasma membrane, 0005622=intracellular" "cg9430, dZip42C.2, CG9430, dZip2" IPR003689=Zinc/iron permease CG9430 16-Dec-15 2015_12 ENSDARG00000058257(slc39a1) "YLR130C(ZRT2),YGL255W(ZRT1)" "WBGene00018897(F55F8.9),WBGene00017936(F30B5.7),WBGene00014669(C06G8.3),WBGene00013207(Y54G9A.4)" "ENSXETG00000001746(SLC39A2),ENSXETG00000004651(slc39a1),ENSXETG00000019914(TEgg075o04.1),ENSXETG00000003715(SLC39A3)" "ENSMUSG00000052310(Slc39a1),ENSMUSG00000046822(Slc39a3),ENSMUSG00000072572(Slc39a2)" "ENSG00000143570(SLC39A1),ENSG00000141873(SLC39A3)" "partially lethal - majority die,some die during pupal stage,lethal - all die during pupal stage,viable,lethal - all die during larval stage" FBgn0014324 l(3)ry3 lethal (3) ry3 http://flybase.net/reports/FBgn0014324.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015995 l(2)k08807 lethal (2) k08807 http://flybase.net/reports/FBgn0015995.html gene 16-Dec-15 2015_12 "lethal,recessive" presumptive embryonic/larval peripheral nervous system FBgn0038173 Adgf-C Adenosine deaminase-related growth factor C http://flybase.net/reports/FBgn0038173.html protein_coding_gene "0008083=growth factor activity, 0004000=adenosine deaminase activity" "0043103=hypoxanthine salvage, 0046103=inosine biosynthetic process, 0008283=cell proliferation, 0006154=adenosine catabolic process" "0005615=extracellular space, 0005576=extracellular region, 0005829=cytosol" "CG9345, ADGF-C, adgfc, AdgfC" "IPR001365=Adenosine/AMP deaminase domain, IPR013659=Adenosine/AMP deaminase N-terminal, IPR006331=Adenosine deaminase-related growth factor" CG9345 16-Dec-15 2015_12 ENSXETG00000000874(CECR1) viable FBgn0003114 plu plutonium http://flybase.net/reports/FBgn0003114.html FBgn0034492 protein_coding_gene 0003677=DNA binding "0007338=single fertilization, 0007343=egg activation, 0008156=negative regulation of DNA replication, 0007346=regulation of mitotic cell cycle" 1902554=serine/threonine protein kinase complex "CG9183, Plu, PLU" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG9183 16-Dec-15 2015_12 embryonic stage | 0-6 hr "lethal,maternal effect,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,female sterile,meiotic cell cycle defective" "nucleus | embryonic stage,oocyte nucleus,nuclear chromosome,male pronucleus,female pronucleus,polar body nucleus,pronucleus" FBgn0040717 Nplp4 Neuropeptide-like precursor 4 http://flybase.net/reports/FBgn0040717.html protein_coding_gene 0005184=neuropeptide hormone activity 0007218=neuropeptide signaling pathway 0005576=extracellular region "CG15361, NPLP4, YSY, YSY peptide, neuropeptide-like precursor 4" CG15361 16-Dec-15 2015_12 viable DRSC00391 K 0.125492502 0.573520674 0.99485833 0.041946835 0.886170861 1.982170871 FBgn0266443 CG45073 http://flybase.net/reports/FBgn0266443.html protein_coding_gene CG18682 IPR006631=Protein of unknown function DM4/12 CG45073 16-Dec-15 2015_12 FBgn0039108 CG10232 http://flybase.net/reports/FBgn0039108.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP14 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG10232 16-Dec-15 2015_12 WBGene00006621(try-3) viable FBgn0035087 CG2765 http://flybase.net/reports/FBgn0035087.html protein_coding_gene 0017022=myosin binding IPR009786=Spot 14 family CG2765 16-Dec-15 2015_12 "ENSDARG00000018145(mid1ip1),ENSDARG00000019302(mid1ip1b),ENSDARG00000041051(mid1ip1a)" "ENSXETG00000008590(mid1ip1),ENSXETG00000007609()" ENSMUSG00000008035(Mid1ip1) ENSG00000165175(MID1IP1) viable FBgn0053558 mim missing-in-metastasis http://flybase.net/reports/FBgn0053558.html "FBgn0025255, FBgn0033118, FBgn0053352, FBtr0086193, FBpp0085520" protein_coding_gene "0042803=protein homodimerization activity, 0003779=actin binding, 0017124=SH3 domain binding, 0005543=phospholipid binding" "0007298=border follicle cell migration, 0008354=germ cell migration, 0007015=actin filament organization, 0007009=plasma membrane organization, 0046847=filopodium assembly, 0048261=negative regulation of receptor-mediated endocytosis" 0043234=protein complex "dmim, CG33558, MIM, anon-fast-evolving-1E4, Dm_2R:10851, CG33352, CG9469, anon-EST:fe1E4, missing-in-metastasis, Mim" "IPR013606=IMD/I-BAR domain, IPR030127=I-BAR domain containing protein MIM/ABBA" CG33558 16-Dec-15 2015_12 "ENSMUSG00000022353(Mtss1),ENSMUSG00000033763(Mtss1l)" "ENSG00000170873(MTSS1),ENSG00000132613(MTSS1L)" "female sterile,partially,locomotor behavior defective,viable" "border follicle cell,germline cell" FBgn0058263 MFS17 Major Facilitator Superfamily Transporter 17 http://flybase.net/reports/FBgn0058263.html "FBgn0045791, FBan0040263" protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "bs24e02.y1, CG40263, BEST:LD07241" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG40263 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" FBgn0010643 l(2)07837 lethal (2) 07837 http://flybase.net/reports/FBgn0010643.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035047 Pof Painting of fourth http://flybase.net/reports/FBgn0035047.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0005515=protein binding, 0003682=chromatin binding" "0005694=chromosome, 0030849=autosome" "painting of fourth, Painting of Fourth, painting of fourth chromosome, pof, cg3691, painting on the fourth, POF, painting-of-fourth, CG3691" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG3691 16-Dec-15 2015_12 "viable,wild-type" FBgn0065581 l(2)SH0941 lethal (2) SH0941 http://flybase.net/reports/FBgn0065581.html gene l(2)SH2 0941 16-Dec-15 2015_12 "lethal,recessive" FBgn0033721 CG13159 http://flybase.net/reports/FBgn0033721.html FBgn0063047 protein_coding_gene BcDNA:RE25177 CG13159 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum DRSC06283 EK -0.60517028 -0.955956894 1.636995156 0.130856873 2.159841255 0.55996082 FBgn0051131 CG31131 http://flybase.net/reports/FBgn0051131.html protein_coding_gene CG31131 16-Dec-15 2015_12 FBgn0043559 Su(roDOM)1480 Su(roDOM)1480 http://flybase.net/reports/FBgn0043559.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0063598 CS3-1 "Calcineurin suppressor, chromosome 3, group 1" http://flybase.net/reports/FBgn0063598.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050203 CG30203 http://flybase.net/reports/FBgn0050203.html FBgn0033711 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "CG17740, CT39323" "IPR009465=Spondin, N-terminal, IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR002861=Reeler domain, IPR000884=Thrombospondin type-1 (TSP1) repeat" CG30203 16-Dec-15 2015_12 "ENSDARG00000023694(spon1b),ENSDARG00000010029(spon1a)" ENSXETG00000009063(SPON1) ENSMUSG00000038156(Spon1) ENSG00000152268(SPON1) viable DRSC06690 K -0.252730836 -0.12889358 0.101228917 0.287352377 2.769842121 1.284844502 FBgn0260049 flr flare http://flybase.net/reports/FBgn0260049.html "FBgn0000676, FBgn0036357" protein_coding_gene 0003779=actin binding "0045214=sarcomere organization, 0035317=imaginal disc-derived wing hair organization, 0030833=regulation of actin filament polymerization, 0006909=phagocytosis, 0008154=actin polymerization or depolymerization, 0034316=negative regulation of Arp2/3 complex-mediated actin nucleation, 0030042=actin filament depolymerization, 0007298=border follicle cell migration" "aip1, CG10724, actin interacting protein 1, flare hair, actin-interacting protein 1, AIP1, Aip1" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR013979=Translation initiation factor, beta propellor-like domain" CG10724 16-Dec-15 2015_12 YMR092C(AIP1) "WBGene00010685(aipl-1),WBGene00006810(unc-78)" ENSXETG00000000629(WDR1) ENSMUSG00000005103(Wdr1) ENSG00000071127(WDR1) FBgn0035725 Mis12 Mis12 http://flybase.net/reports/FBgn0035725.html FBgn0063053 protein_coding_gene "0007059=chromosome segregation, 0007079=mitotic chromosome movement towards spindle pole, 0007080=mitotic metaphase plate congression, 0022008=neurogenesis, 0007052=mitotic spindle organization" "0031262=Ndc80 complex, 0000776=kinetochore, 0000775=chromosome, centromeric region" "Mis12, BcDNA:RE19545, CG18156, dmMis12, Mis-12" CG18156 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0085799 CR41544 http://flybase.net/reports/FBgn0085799.html FBan0041544 rRNA_gene CR41544 16-Dec-15 2015_12 FBgn0032910 CG9265 http://flybase.net/reports/FBgn0032910.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG9265 16-Dec-15 2015_12 "YDL114W(),YLR426W()" "WBGene00000967(dhs-3),WBGene00000982(dhs-19)" "ENSMUSG00000029311(Hsd17b11),ENSMUSG00000034528(Hsd17b13)" "ENSG00000170786(SDR16C5),ENSG00000121039(RDH10)" "viable,fertile" DRSC03178 E -0.925043617 -0.454212092 -1.792542037 0.463251428 -0.050592619 -0.829007981 FBgn0023056 l(1)2Fg lethal (1) 2Fg http://flybase.net/reports/FBgn0023056.html gene "AS2/11, B2/27.14" 16-Dec-15 2015_12 "lethal,recessive" FBgn0011889 tRNA:K2:42Ac transfer RNA:lys2:42Ac http://flybase.net/reports/FBgn0011889.html "FBgn0003795, FBgn0011886, FBgn0050310, FBgn0050517, FBgn0060186" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033444=AAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30310, tRNA:K:CTT:AE002769-c, 35SLys, CR30517, tRNA:K2, tRNA[Lys][[2]], chr2R.trna96-LysCTT, tRNA:lys2:42Ac, AE002769.trna5-LysCTT, tRNAlys" CR30517 16-Dec-15 2015_12 FBgn0266439 CG45069 http://flybase.net/reports/FBgn0266439.html protein_coding_gene CG3419 CG45069 16-Dec-15 2015_12 viable FBgn0044104 E(rst)C421 E(rst)C421 http://flybase.net/reports/FBgn0044104.html gene 0001745=compound eye morphogenesis C421 16-Dec-15 2015_12 FBgn0015819 Su(KrIf) Suppressor of Kruppel-Irregular facets http://flybase.net/reports/FBgn0015819.html gene 16-Dec-15 2015_12 FBgn0000594 Est-P Esterase P http://flybase.net/reports/FBgn0000594.html FBgn0017620 protein_coding_gene 0052689=carboxylic ester hydrolase activity "Est7, yEst-6, EST-5, PsiEst-6, yEst6, Est-5, est-P, ESTP, psiEst-6, EST7, Est-7, EstP, CG17148" "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site" CG17148 16-Dec-15 2015_12 " larval stage | late , adult stage " "electrophoretic variant,slow,fast,viable,partially lethal - majority die" FBgn0063378 snoRNA:U31:54Ed snoRNA:U31:54Ed http://flybase.net/reports/FBgn0063378.html snoRNA_gene "U31snoRNA, CR32899" CR32899 16-Dec-15 2015_12 FBgn0031897 CG13784 http://flybase.net/reports/FBgn0031897.html FBgn0046986 protein_coding_gene BcDNA:SD10385 IPR006603=PQ-loop repeat CG13784 16-Dec-15 2015_12 ENSDARG00000061997 YMR010W() WBGene00011827(T19A6.1) ENSXETG00000025946(pqlc1) ENSMUSG00000034006(Pqlc1) ENSG00000122490(PQLC1) viable FBgn0086474 l(3)d05983 http://flybase.net/reports/FBgn0086474.html gene 16-Dec-15 2015_12 FBgn0024856 l(3)96Bf lethal (3) 96Bf http://flybase.net/reports/FBgn0024856.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053160 CG33160 http://flybase.net/reports/FBgn0053160.html FBgn0035418 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP183, CG11531" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG33160 16-Dec-15 2015_12 viable FBgn0026189 prominin-like prominin-like http://flybase.net/reports/FBgn0026189.html protein_coding_gene 0048812=neuron projection morphogenesis "0005886=plasma membrane, 0016021=integral component of membrane" "CG7740, Prominin-like, bs29e02.y1, prominin-like protein" IPR008795=Prominin CG7740 16-Dec-15 2015_12 "ENSDARG00000070237,ENSDARG00000039966(prom1a),ENSDARG00000034007(prom1b),ENSDARG00000039406(prom3)" WBGene00008571(F08B12.1) "ENSXETG00000020336(PROM1),ENSXETG00000006272(),ENSXETG00000004342()" "ENSMUSG00000029086(Prom1),ENSMUSG00000027376(Prom2)" ENSG00000007062(PROM1) FBgn0264655 oak-gall oak gall http://flybase.net/reports/FBgn0264655.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0032491 CG16815 http://flybase.net/reports/FBgn0032491.html protein_coding_gene 0046983=protein dimerization activity DM27 CG16815 16-Dec-15 2015_12 viable FBgn0036152 CG6175 http://flybase.net/reports/FBgn0036152.html FBgn0063796 protein_coding_gene "0002121=inter-male aggressive behavior, 0007476=imaginal disc-derived wing morphogenesis, 0051726=regulation of cell cycle" anon-WO0257455.23 IPR006578=MADF domain CG6175 16-Dec-15 2015_12 "behavior defective,recessive,partially lethal - majority die" FBgn0030094 CG11042 http://flybase.net/reports/FBgn0030094.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039749 CG11498 http://flybase.net/reports/FBgn0039749.html protein_coding_gene 0033554=cellular response to stress 0005741=mitochondrial outer membrane IPR026169=Mitochondria-eating protein CG11498 16-Dec-15 2015_12 WBGene00018641(F49E10.4) viable DRSC14315 E -0.48285746 0.163927676 3.171273854 0.461518065 0.81556617 0.224525858 FBgn0067379 l(2)309 lethal (2) 309 http://flybase.net/reports/FBgn0067379.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0042169 CG18849 http://flybase.net/reports/FBgn0042169.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060622 l(3)S088113 lethal (3) S088113 http://flybase.net/reports/FBgn0060622.html gene 0881/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0261915 l(3)16107 http://flybase.net/reports/FBgn0261915.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" FBgn0033316 CG14749 http://flybase.net/reports/FBgn0033316.html protein_coding_gene 0016973=poly(A)+ mRNA export from nucleus "0005643=nuclear pore, 0005739=mitochondrion" "Gle1, GLE1" IPR012476=GLE1-like CG14749 16-Dec-15 2015_12 ENSDARG00000043559(gle1l) YDL207W(GLE1) ENSXETG00000006584(GLE1) ENSMUSG00000019715(Gle1) ENSG00000119392(GLE1) viable FBgn0062675 EP2433 EP2433 http://flybase.net/reports/FBgn0062675.html gene EP(2)2433 16-Dec-15 2015_12 FBgn0004147 l(2)57Aa lethal (2) 57Aa http://flybase.net/reports/FBgn0004147.html gene 16-Dec-15 2015_12 "lethal,visible,recessive" FBgn0043860 pf-6 pairing failure-6 http://flybase.net/reports/FBgn0043860.html gene 0007140=male meiosis "Complementation group 6, CG6" 16-Dec-15 2015_12 FBgn0034759 CG13511 http://flybase.net/reports/FBgn0034759.html protein_coding_gene IPR006629=LPS-induced tumour necrosis factor alpha factor CG13511 16-Dec-15 2015_12 viable FBgn0011664 ms(2)1400 ms(2)1400 http://flybase.net/reports/FBgn0011664.html gene 16-Dec-15 2015_12 FBgn0266515 s-562.2 http://flybase.net/reports/FBgn0266515.html gene 16-Dec-15 2015_12 FBgn0031466 CG3119 http://flybase.net/reports/FBgn0031466.html protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" 0016020=membrane dC1GalT7 IPR003378=Fringe-like CG3119 16-Dec-15 2015_12 viable FBgn0061089 l(3)S011513a lethal (3) S011513a http://flybase.net/reports/FBgn0061089.html gene 0115/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0260600 2L2775 http://flybase.net/reports/FBgn0260600.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0039024 CG4721 http://flybase.net/reports/FBgn0039024.html FBgn0027758 protein_coding_gene 0004222=metalloendopeptidase activity "0006508=proteolysis, 0001745=compound eye morphogenesis" anon-EST:Posey132 "IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain" CG4721 16-Dec-15 2015_12 visible eye FBgn0054030 CG34030 http://flybase.net/reports/FBgn0054030.html FBgn0082656 protein_coding_gene "HDC08855, unnamed, BP1084" CG34030 16-Dec-15 2015_12 FBgn0022730 l(2)PGM-21 lethal (2) PGM-21 http://flybase.net/reports/FBgn0022730.html gene PGM-21 16-Dec-15 2015_12 "lethal,recessive" FBgn0014257 l(2)FE3 lethal (2) FE3 http://flybase.net/reports/FBgn0014257.html gene FE3 16-Dec-15 2015_12 "lethal,recessive" FBgn0002582 M(1)5A Minute (1) 5A http://flybase.net/reports/FBgn0002582.html gene 16-Dec-15 2015_12 FBgn0032940 Mondo Mondo http://flybase.net/reports/FBgn0032940.html FBgn0041170 protein_coding_gene "0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0070328=triglyceride homeostasis, 0006355=regulation of transcription, DNA-templated, 0042593=glucose homeostasis, 0006357=regulation of transcription from RNA polymerase II promoter, 0009744=response to sucrose" "0005829=cytosol, 0005634=nucleus, 0005667=transcription factor complex" "Mondo, Mio, WBSCR14-related, ChREBP, 154826_at, CG18362, mio, dmondo, Mlx interactor, anon-39Da, unnamed, bHLHd12" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG18362 16-Dec-15 2015_12 WBGene00003378(mml-1) "ENSMUSG00000038342(Mlxip),ENSMUSG00000005373(Mlxipl)" "ENSG00000175727(MLXIP),ENSG00000009950(MLXIPL)" "lethal,recessive,feeding behavior defective,viable,fertile,developmental rate defective,conditional,partially lethal,lethal - all die during larval stage,chemical conditional,stress response defective,chemical sensitive,small body" DRSC02668 IEK -1.692120041 -1.219683889 -1.303151459 -1.73792302 -0.136675375 -1.661653564 FBgn0266414 CR45054 http://flybase.net/reports/FBgn0266414.html non_protein_coding_gene CG45054 CR45054 16-Dec-15 2015_12 FBgn0039224 CG13634 http://flybase.net/reports/FBgn0039224.html protein_coding_gene CG13634 16-Dec-15 2015_12 viable FBgn0011593 fs(3)2877 fs(3)2877 http://flybase.net/reports/FBgn0011593.html gene 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0025791 Su(var)b601 Suppressor of variegation b601 http://flybase.net/reports/FBgn0025791.html gene Su-var(2)b601 16-Dec-15 2015_12 FBgn0259166 CG42271 http://flybase.net/reports/FBgn0259166.html "FBgn0053248, FBgn0030553, FBgn0053249" protein_coding_gene "0016316=phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity" 0046856=phosphatidylinositol dephosphorylation "CG33249, INPP4A, CG1846, FBgn0259166, CG33248" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain, IPR000008=C2 domain" CG42271 16-Dec-15 2015_12 WBGene00010975(R01H10.7) "ENSXETG00000019407(INPP4A),ENSXETG00000021313(INPP4B)" "ENSMUSG00000026113(Inpp4a),ENSMUSG00000037940(Inpp4b)" "ENSG00000040933(INPP4A),ENSG00000109452(INPP4B)" FBgn0040185 l(1)G0226 lethal (1) G0226 http://flybase.net/reports/FBgn0040185.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,chaeta" FBgn0033981 Cyp6a21 Cyp6a21 http://flybase.net/reports/FBgn0033981.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "cytochrome P450, 6a21, cyp6a21, Cytochrome P450 6a21, CG10247" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG10247 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0037172 ND-B14.5AL NADH dehydrogenase (ubiquinone) B14.5 A subunit-like http://flybase.net/reports/FBgn0037172.html FBgn0063336 protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0042773=ATP synthesis coupled electron transport 0005747=mitochondrial respiratory chain complex I "N4AM, NADH:ubiquinone oxidoreductase B14.5A subunit, BcDNA:AT13913, CG6914, NADH-ubiquinone oxidoreductase subunit B14.5a" IPR009947=NADH:ubiquinone oxidoreductase subunit B14.5a CG6914 16-Dec-15 2015_12 ENSDARG00000036684(zgc:92850) ENSMUSG00000041881(Ndufa7) ENSG00000167774(NDUFA7) viable FBgn0263505 CR43494 http://flybase.net/reports/FBgn0263505.html non_protein_coding_gene CR43494 16-Dec-15 2015_12 FBgn0034070 SP2353 SP2353 http://flybase.net/reports/FBgn0034070.html FBgn0063254 protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0042052=rhabdomere development, 0046716=muscle cell cellular homeostasis, 0045824=negative regulation of innate immune response" 0005615=extracellular space "CG8403, agrin-like, BcDNA:GH12319, CT18665" "IPR013032=EGF-like, conserved site, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000742=EGF-like domain" CG8403 16-Dec-15 2015_12 WBGene00020581(T19D12.6) ENSXETG00000013228(EGFLAM) viable FBgn0028157 l(3)S041919 lethal (3) S041919 http://flybase.net/reports/FBgn0028157.html gene 0419/19 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0038275 CG3817 http://flybase.net/reports/FBgn0038275.html protein_coding_gene 0022008=neurogenesis IPR012459=Protein of unknown function DUF1665 CG3817 16-Dec-15 2015_12 ENSDARG00000013478(rrp15) ENSMUSG00000001305(Rrp15) ENSG00000067533(RRP15) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC15515 K -0.016082646 0.032359987 0.455390794 -0.105585825 -1.899419552 0.385474073 FBgn0040484 BobD Brother of Brd D http://flybase.net/reports/FBgn0040484.html gene "Bob, Brother of Bearded" 16-Dec-15 2015_12 FBgn0020822 l(3)98Dh lethal (3) 98Dh http://flybase.net/reports/FBgn0020822.html gene M315 16-Dec-15 2015_12 "lethal,recessive" FBgn0020565 anon-EB8 anon-EB8 http://flybase.net/reports/FBgn0020565.html gene 16-Dec-15 2015_12 FBgn0001195 His1 Histone H1 http://flybase.net/reports/FBgn0001195.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0031057=negative regulation of histone modification, 0051276=chromosome organization, 0006334=nucleosome assembly, 0006342=chromatin silencing" "0000786=nucleosome, 0005634=nucleus" "his, histone, H1A, H1, HisC, dH1, DmeH1, Histone, histone H1, hisl" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5" 16-Dec-15 2015_12 lethal "polytene chromosomeda.G32,polytene chromosome chromocenterda.G32" FBgn0013584 l(3)92Ea lethal (3) 92Ea http://flybase.net/reports/FBgn0013584.html gene AS416 16-Dec-15 2015_12 "lethal,recessive" FBgn0040089 meso18E meso18E http://flybase.net/reports/FBgn0040089.html "FBgn0019899, FBgn0031063, FBgn0040223" protein_coding_gene 0007498=mesoderm development "CG14233, anon-18DEd, eso18E, ld26007, Dmeso18E, Meso18E, Mmeso18E" CG14233 16-Dec-15 2015_12 "viable,fertile" FBgn0263738 Ada2a transcriptional Adaptor 2a http://flybase.net/reports/FBgn0263738.html "FBgn0053520, FBgn0038591, FBgn0051318, FBgn0062038" protein_coding_gene "0004402=histone acetyltransferase activity, 0003677=DNA binding, 0008270=zinc ion binding" "0006338=chromatin remodeling, 0006357=regulation of transcription from RNA polymerase II promoter, 0043966=histone H3 acetylation, 0043967=histone H4 acetylation, 0016573=histone acetylation" "0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0035327=transcriptionally active chromatin, 0005634=nucleus" "dADA2a, dAda2A, CG7150, CG33520, CG31318, Ada2A, dAda2a, DmADA2a, ada2a, CG43663, ADA2a, DmAda2a" "IPR000433=Zinc finger, ZZ-type, IPR009057=Homeodomain-like, IPR007526=SWIRM domain, IPR001005=SANT/Myb domain, IPR017877=Myb-like domain, IPR016827=Transcriptional adaptor 2" CG43663 16-Dec-15 2015_12 "lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable,lethal" FBgn0010772 Xe7 Xe7 http://flybase.net/reports/FBgn0010772.html FBgn0037362 protein_coding_gene 0000166=nucleotide binding "0007411=axon guidance, 0046331=lateral inhibition" "CG2179, l(3)02248" IPR012677=Nucleotide-binding alpha-beta plait domain CG2179 16-Dec-15 2015_12 ENSDARG00000003384 WBGene00000854(cux-7) ENSMUSG00000059708(Srsf17b) ENSG00000197976(AKAP17A) "lethal,neuroanatomy defective,somatic clone,recessive,viable,visible" "chaeta,supernumerary" FBgn0029502 COQ7 COQ7 http://flybase.net/reports/FBgn0029502.html FBgn0029900 protein_coding_gene "0006744=ubiquinone biosynthetic process, 0055114=oxidation-reduction process" 0005739=mitochondrion "Dclk1, CG14437" "IPR012347=Ferritin-related, IPR009078=Ferritin-like superfamily, IPR011566=Ubiquinone biosynthesis protein Coq7" CG14437 16-Dec-15 2015_12 ENSDARG00000062594(zgc:158731) YOR125C(CAT5) WBGene00000536(clk-1) ENSXETG00000002946(coq7) ENSG00000167186(COQ7) "developmental rate defective,RU486 conditional,short lived,female,viable" FBgn0011981 tRNA:S774:12Ef transfer RNA:ser774:12Ef http://flybase.net/reports/FBgn0011981.html "FBgn0003830, FBgn0011968, FBgn0052618, FBgn0060070" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033405=UCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:ser, tRNA:ser774:12Ef, 774-2, chrX.trna13-SerAGA, transfer RNA:ser, AE002593.trna9-SerAGA, tRNA[[Ser]], unnamed, tRNA:S:AGA:AE002593-b, tRNA:S, CR32618, Ser-tRNA-4-7" CR32618 16-Dec-15 2015_12 FBgn0014113 anon-84Bb anon-84Bb http://flybase.net/reports/FBgn0014113.html gene Y3 16-Dec-15 2015_12 " embryonic stage&&larval stage&&pupal stage , adult stage && oogenesis stage " unfertilized egg

FBgn0001919 l(2)25Bf lethal (2) 25Bf http://flybase.net/reports/FBgn0001919.html gene "jf15, l(2)jf15" 16-Dec-15 2015_12 lethal FBgn0003916 snRNA:U1:21D small nuclear RNA U1 at 21D http://flybase.net/reports/FBgn0003916.html "FBgn0003915, FBgn0026794, FBgn0051656" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005685=U1 snRNP "U1, dU1, 21E U1, small nuclear RNA U1, U1a-21D, U1a1(AT)[[15]], K5, U1-21D, U1 snRNA, U14, snRNA1, CR31656, U1snRNA21D, U1-1, U1a, U1snRNA, snRNA:U1, U1-21.1, U1 small nuclear RNA, U1:21D, U1 21D, snRNA-U1-21.1" CR31656 16-Dec-15 2015_12 "lethal,recessive" FBgn0052553 CG32553 http://flybase.net/reports/FBgn0052553.html protein_coding_gene CG32553 16-Dec-15 2015_12 FBgn0039688 Kul Kuzbanian-like http://flybase.net/reports/FBgn0039688.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0008593=regulation of Notch signaling pathway, 0006509=membrane protein ectodomain proteolysis" 0016021=integral component of membrane "ADAM10, CT3146, CG1964" "IPR002870=Peptidase M12B, propeptide, IPR024079=Metallopeptidase, catalytic domain, IPR001590=Peptidase M12B, ADAM/reprolysin, IPR001762=Disintegrin domain" CG1964 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "wing,wing margin,wing vein,wing hair,supernumerary,interfollicle cell,trichogen cell,mesothoracic tergum" FBgn0036911 Fibp Fibp http://flybase.net/reports/FBgn0036911.html protein_coding_gene 0017134=fibroblast growth factor binding 0005622=intracellular "DrFIBP, CG8660, F1bp" IPR008614=Acidic fibroblast growth factor intracellular-binding protein CG8660 16-Dec-15 2015_12 "ENSDARG00000025648(fibpl),ENSDARG00000016058(fibp)" ENSXETG00000020596(FIBP) ENSMUSG00000024911(Fibp) ENSG00000172500(FIBP) "viable,fertile" FBgn0061188 Yu Yu http://flybase.net/reports/FBgn0061188.html non_protein_coding_gene "yu, CR42645" CR42645 16-Dec-15 2015_12 FBgn0083952 CG34116 http://flybase.net/reports/FBgn0083952.html protein_coding_gene 0003677=DNA binding CG14103 "IPR003656=Zinc finger, BED-type" CG34116 16-Dec-15 2015_12 FBgn0036563 CG13075 http://flybase.net/reports/FBgn0036563.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13075 16-Dec-15 2015_12 viable FBgn0062577 Mod(var)E1060 Mod(var)E1060 http://flybase.net/reports/FBgn0062577.html gene 0006342=chromatin silencing E1060 16-Dec-15 2015_12 "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0001703 l(1)ESHS24 lethal (1) ESHS24 http://flybase.net/reports/FBgn0001703.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037163 laza lazaro http://flybase.net/reports/FBgn0037163.html protein_coding_gene 0008195=phosphatidate phosphatase activity "0016311=dephosphorylation, 0007602=phototransduction, 0009642=response to light intensity, 0043052=thermotaxis" 0016020=membrane "Laza, Lazaro, LPP-like, CG11440, WUN-like, LPP" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG11440 16-Dec-15 2015_12 "neurophysiology defective,viable,fertile,thermotaxis behavior defective" "eye,rhabdomere" FBgn0052279 Drsl2 Drosomycin-like 2 http://flybase.net/reports/FBgn0052279.html FBgn0035433 protein_coding_gene "0050832=defense response to fungus, 0042832=defense response to protozoan, 0006952=defense response" 0005576=extracellular region "Drosomycin 2, Drosomycin-2, Drosomycin-like D, CT30310, CG32279, dmy2, CG10813, dro2, drosomycin-2, Dro-D, Dro2, drosomycin-D, dro-2, drosomycin, Drs-lD" "IPR003614=Knottin, scorpion toxin-like" CG32279 16-Dec-15 2015_12 viable DRSC08160 K 0.124052137 -0.889620755 0.224185389 -0.515382324 0.292733133 1.710552507 FBgn0015427 l(1)1Fg lethal (1) 1Fg http://flybase.net/reports/FBgn0015427.html gene "4-134, D42" 16-Dec-15 2015_12 "lethal,recessive" FBgn0259193 Ir94d Ionotropic receptor 94d http://flybase.net/reports/FBgn0259193.html "FBgn0039076, FBan0017379" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "IR94d, CG17379, CG42297, ionotropic receptor 94d, DmelIR94d" CG42297 16-Dec-15 2015_12 FBgn0028670 Vha100-2 Vacuolar H+ ATPase 100kD subunit 2 http://flybase.net/reports/FBgn0028670.html "FBgn0027516, FBgn0038615, FBgn0038616, FBgn0062113" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0005886=plasma membrane, 0033181=plasma membrane proton-transporting V-type ATPase complex, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "vha100-2, Vacuolar H + ATPase subunit 100-2, CG18617, Vha100-2, anon-WO0118547.296, BcDNA:LD21735, CG7679, Vacuolar H[+] ATPase subunit 100-2" "IPR026028=ATPase, V0 complex, subunit 116kDa, eukaryotic, IPR002490=V-type ATPase, V0 complex, 116kDa subunit family" CG18617 16-Dec-15 2015_12 "YOR270C(VPH1),YMR054W(STV1)" "viable,lethal,recessive,fertile,visible" "chaeta,supernumerary" FBgn0259387 C255 http://flybase.net/reports/FBgn0259387.html gene 16-Dec-15 2015_12 "visible,lethal" "wing hair,chaeta" FBgn0005303 Mot-K Mottled K http://flybase.net/reports/FBgn0005303.html gene Mo[K] 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" eye FBgn0050050 CG30050 http://flybase.net/reports/FBgn0050050.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG30050 16-Dec-15 2015_12 viable FBgn0262896 CG43251 http://flybase.net/reports/FBgn0262896.html protein_coding_gene lincRNA.639 CG43251 16-Dec-15 2015_12 FBgn0052324 tRNA:CR32324 transfer RNA:CR32324 http://flybase.net/reports/FBgn0052324.html FBgn0060247 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna9-GluCTC, AE002584.trna9-GluCTC, CR32324, tRNA:E:CTC:AE002584-g" CR32324 16-Dec-15 2015_12 FBgn0067088 J18 J18 http://flybase.net/reports/FBgn0067088.html gene 16-Dec-15 2015_12 "visible,partially lethal - majority die,viable" eye FBgn0259435 EP-767.1 http://flybase.net/reports/FBgn0259435.html gene 16-Dec-15 2015_12 visible wing vein FBgn0267541 CR45881 http://flybase.net/reports/FBgn0267541.html non_protein_coding_gene CR45881 16-Dec-15 2015_12 FBgn0264393 CG43841 http://flybase.net/reports/FBgn0264393.html protein_coding_gene CG32551 CG43841 16-Dec-15 2015_12 FBgn0010933 l(3)09143 lethal (3) 09143 http://flybase.net/reports/FBgn0010933.html gene l(3)9143 16-Dec-15 2015_12 "lethal,recessive" FBgn0067905 IM14 Immune induced molecule 14 http://flybase.net/reports/FBgn0067905.html FBgn0053990 protein_coding_gene "0006952=defense response, 0009617=response to bacterium" 0005576=extracellular region "im14, CG33990, DIM 14" CG33990 16-Dec-15 2015_12 FBgn0264539 CR43918 http://flybase.net/reports/FBgn0264539.html non_protein_coding_gene CR43918 16-Dec-15 2015_12 FBgn0005298 mei-G17 meiotic G17 http://flybase.net/reports/FBgn0005298.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive" meiosis I FBgn0035287 CG13937 http://flybase.net/reports/FBgn0035287.html protein_coding_gene 0016232=HNK-1 sulfotransferase activity 0016051=carbohydrate biosynthetic process 0016021=integral component of membrane d4ST2 "IPR005331=Sulfotransferase, IPR018011=Carbohydrate sulfotransferase-related" CG13937 16-Dec-15 2015_12 viable FBgn0260078 2L3651 http://flybase.net/reports/FBgn0260078.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0036183 CG6083 http://flybase.net/reports/FBgn0036183.html protein_coding_gene 0004032=alditol:NADP+ 1-oxidoreductase activity "0055114=oxidation-reduction process, 0016319=mushroom body development" "IPR020471=Aldo/keto reductase subgroup, IPR001395=Aldo/keto reductase, IPR018170=Aldo/keto reductase, conserved site, IPR023210=NADP-dependent oxidoreductase domain" CG6083 16-Dec-15 2015_12 YHR104W(GRE3) "neuroanatomy defective,viable" adult mushroom body DRSC24586 K 0.364844955 -0.05629393 0.593022292 0.681049727 -0.298706111 -1.597114604 FBgn0001808 l(1)Mc56 lethal (1) Mc56 http://flybase.net/reports/FBgn0001808.html gene 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0020788 rABP70 ribosomal 'Alu-repeat' binding protein 70 http://flybase.net/reports/FBgn0020788.html gene 16-Dec-15 2015_12 FBgn0016026 l(3)89Ce lethal (3) 89Ce http://flybase.net/reports/FBgn0016026.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265426 CR44338 http://flybase.net/reports/FBgn0265426.html non_protein_coding_gene CG44338 CR44338 16-Dec-15 2015_12 FBgn0016069 slinky slinky http://flybase.net/reports/FBgn0016069.html gene 0007422=peripheral nervous system development unnamed 16-Dec-15 2015_12 FBgn0050045 Cpr49Aa Cuticular protein 49Aa http://flybase.net/reports/FBgn0050045.html FBgn0033722 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG30045, DmelCpr49Aa, CG8496" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG30045 16-Dec-15 2015_12 FBgn0011151 l(1)Q227 lethal (1) Q227 http://flybase.net/reports/FBgn0011151.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0038880 SIFaR SIFamide receptor http://flybase.net/reports/FBgn0038880.html "FBgn0046533, FBgn0046534" protein_coding_gene "0004930=G-protein coupled receptor activity, 0004983=neuropeptide Y receptor activity, 0008528=G-protein coupled peptide receptor activity, 0008188=neuropeptide receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan, 0007218=neuropeptide signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "DrmSIFR, SIFamide-receptor, SIFa-R, anon-WO0170980.43, SIF-R, anon-WO0170980.44, CG10823, SIFR" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR000611=Neuropeptide Y receptor family, IPR017452=GPCR, rhodopsin-like, 7TM" CG10823 16-Dec-15 2015_12 "ENSDARG00000035236(npffr2.1),ENSDARG00000060702,ENSDARG00000033635(LOC564758)" "ENSG00000056291(NPFFR2),ENSG00000148734(NPFFR1)" "long lived,viable" FBgn0264410 FCE-C http://flybase.net/reports/FBgn0264410.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0031673 CG31650 http://flybase.net/reports/FBgn0031673.html FBgn0051650 protein_coding_gene 0005509=calcium ion binding 0007030=Golgi organization "0005788=endoplasmic reticulum lumen, 0005783=endoplasmic reticulum" "CG9112, RCN2" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG31650 16-Dec-15 2015_12 WBGene00017240(F08B6.3) ENSXETG00000006019(rcn2) ENSMUSG00000032320(Rcn2) ENSG00000117906(RCN2) viable FBgn0050130 CG30130 http://flybase.net/reports/FBgn0050130.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263764 CR43681 http://flybase.net/reports/FBgn0263764.html non_protein_coding_gene "lincRNA.108, Dm_2L:52920, CR43681, CG43681" CR43681 16-Dec-15 2015_12 FBgn0010189 tu-47 tu-47 http://flybase.net/reports/FBgn0010189.html gene 16-Dec-15 2015_12 FBgn0266003 CR44777 http://flybase.net/reports/FBgn0266003.html non_protein_coding_gene CR44777 16-Dec-15 2015_12 FBgn0002323 l(3)86Fb lethal (3) 86Fb http://flybase.net/reports/FBgn0002323.html gene l(3)ck2 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0261671 tweek tweek http://flybase.net/reports/FBgn0261671.html "FBgn0084472, FBgn0260757, FBan0015133, FBgn0032619, FBgn0032621, FBgn0032622, FBan0015134, FBgn0261623" protein_coding_gene 0048488=synaptic vesicle endocytosis "Tweek, CG15133, CG42706, CG4841, CG15134, CG42555" "IPR018863=Fragile site-associated protein, C-terminal" CG42555 16-Dec-15 2015_12 WBGene00003060(lpd-3) ENSXETG00000000994() ENSMUSG00000037270(4932438A13Rik) FBgn0036168 CG7512 http://flybase.net/reports/FBgn0036168.html protein_coding_gene 0046872=metal ion binding "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG7512 16-Dec-15 2015_12 viable FBgn0037992 CG4702 http://flybase.net/reports/FBgn0037992.html protein_coding_gene 4702 IPR006631=Protein of unknown function DM4/12 CG4702 16-Dec-15 2015_12 "viable,fertile" FBgn0039722 Capa Capability http://flybase.net/reports/FBgn0039722.html FBgn0016129 protein_coding_gene "0071855=neuropeptide receptor binding, 0005184=neuropeptide hormone activity, 0008613=diuretic hormone activity, 0016084=myostimulatory hormone activity, 0005102=receptor binding" "0042045=epithelial fluid transport, 0008016=regulation of heart contraction, 0007218=neuropeptide signaling pathway, 0007204=positive regulation of cytosolic calcium ion concentration, 0038060=nitric oxide-cGMP-mediated signaling pathway, 0006812=cation transport" 0005615=extracellular space "cardio acceleratory peptide, Periviscerokinin, CAP2b-3, CAPA-PVK-2, capability, Cap-2b, Drm-PVK-2, CAP2B/pyrokinin, Capa, CAP2b, pyrokinin-like, CAPA-PVK-1, capa-1, CG15520, myotropin-CAP2b-like, Capa-2, Drm-capa-1, Drm-PK-1, cap2b-like, pyrokinin/PBAN-like, Pyrokinin, capa-3, Drm-PVK-1, CAPA-PK, CPPB, Drm-PVK, Cap-3, TGPSASSGLWFGPRLamide, CAP-2b, CAPA, CAP, Drm-MT, capa 2, capa-2, CAP2b-1, Drm-CAP-2, CAP2b-2, capa, Drm-myotropin, Cap-2, Cardioacceleratory peptide-2b, CAP2B-3, CAPA-PVK/PK, Cap-1, pyrokinin-1, CAP2B-2, Drm-PK, CAP2B-1, pyrokinin, Capa-1, CAP2B-like, Drm-CAP2b/MT, Drm-CAP-1, PVK-2, CAP[[2b]], myotropin" CG15520 16-Dec-15 2015_12 viable FBgn0051858 t-cup tetleys-cup http://flybase.net/reports/FBgn0051858.html protein_coding_gene "tetleys-cup, cup, t-cup, CG31858" IPR001199=Cytochrome b5-like heme/steroid binding domain CG31858 16-Dec-15 2015_12 viable DRSC01254 I 1.741319522 1.652263905 0.622614721 1.084253099 -0.24252598 -0.043542791 FBgn0038145 Droj2 DnaJ-like-2 http://flybase.net/reports/FBgn0038145.html FBgn0062036 protein_coding_gene "0051082=unfolded protein binding, 0031072=heat shock protein binding, 0005524=ATP binding" "0009408=response to heat, 0006457=protein folding, 0022008=neurogenesis" "CG8863, DnaJ-like-2, anon-WO0118547.404, DnaJ-like-2 chaperone, DROJ2" "IPR002939=Chaperone DnaJ, C-terminal, IPR001305=Heat shock protein DnaJ, cysteine-rich domain, IPR012724=Chaperone DnaJ, IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site, IPR008971=HSP40/DnaJ peptide-binding" CG8863 16-Dec-15 2015_12 "ENSDARG00000051762,ENSDARG00000030972(dnaja1l)" YNL064C(YDJ1) WBGene00001030(dnj-12) "ENSXETG00000024144(dnaja1),ENSXETG00000016946(DNAJA4)" "ENSMUSG00000032285(Dnaja4),ENSMUSG00000028410(Dnaja1)" "ENSG00000140403(DNAJA4),ENSG00000086061(DNAJA1)" "lethal,neuroanatomy defective" ganglion mother cell DRSC16450 I 1.533035775 2.653205633 -1.252964288 0.49932945 -1.285512664 -0.083718323 FBgn0037417 Osi10 Osiris 10 http://flybase.net/reports/FBgn0037417.html protein_coding_gene 0005887=integral component of plasma membrane "CG15593, Osiris" IPR012464=Protein of unknown function DUF1676 CG15593 16-Dec-15 2015_12 viable DRSC12279 I 1.427297196 1.537261355 0.567794344 0.155738551 0.54609664 -0.093914367 FBgn0003732 Top2 Topoisomerase 2 http://flybase.net/reports/FBgn0003732.html protein_coding_gene "0003682=chromatin binding, 0003677=DNA binding, 0003918=DNA topoisomerase type II (ATP-hydrolyzing) activity, 0005524=ATP binding, 0000400=four-way junction DNA binding, 0005515=protein binding, 0000182=rDNA binding, 0003696=satellite DNA binding, 0003729=mRNA binding" "0051310=metaphase plate congression, 0007095=mitotic G2 DNA damage checkpoint, 0006261=DNA-dependent DNA replication, 0006312=mitotic recombination, 0000712=resolution of meiotic recombination intermediates, 0007126=meiotic nuclear division, 0000819=sister chromatid segregation, 0007076=mitotic chromosome condensation, 0000070=mitotic sister chromatid segregation, 0006342=chromatin silencing, 0007067=mitotic nuclear division, 0006265=DNA topological change, 0007052=mitotic spindle organization" "0000795=synaptonemal complex, 0000793=condensed chromosome, 0016590=ACF complex, 0008623=CHRAC, 0009295=nucleoid, 0005634=nucleus, 0005694=chromosome" "DNA topoisomerase II, dTopoII, topo II, Top 2, type II DNA topoisomerase, DNA Topoisomeriase II, top2, topoII, TOPOII, TOP2, TopII, type II topoisomerase, TopoII, CHRAC, Topoisomerase II, topoisomerase II, TOPO II, CG10223, dCHRAC, Topo II, Topoisomerase2" "IPR006171=Toprim domain, IPR003594=Histidine kinase-like ATPase, C-terminal domain, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR001241=DNA topoisomerase, type IIA, IPR013757=Type IIA DNA topoisomerase subunit A, alpha-helical domain, IPR024946=Arginine repressor C-terminal-like domain, IPR013759=DNA topoisomerase, type IIA, central domain, IPR018522=DNA topoisomerase, type IIA, conserved site, IPR002205=DNA topoisomerase, type IIA, subunit A/C-terminal, IPR013506=DNA topoisomerase, type IIA, subunit B, domain 2, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR001154=DNA topoisomerase II, eukaryotic-type, IPR013758=DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta, IPR013760=DNA topoisomerase, type IIA-like domain" CG10223 16-Dec-15 2015_12 ENSDARG00000034195(top2b) YNL088W(TOP2) WBGene00010785(top-2) "ENSXETG00000021362(TOP2A),ENSXETG00000007282(TOP2B)" "ENSMUSG00000020914(Top2a),ENSMUSG00000017485(Top2b)" "ENSG00000077097(TOP2B),ENSG00000131747(TOP2A)" "neuroanatomy defective,somatic clone,lethal,recessive,partially lethal - majority die,male fertile,female sterile,heat sensitive,male sterile,viable,lethal - all die before end of first instar larval stage,lethal - all die before end of second instar larval stage,small body,developmental rate defective,lethal - all die during first instar larval stage,visible" "adult mushroom body,somatic clone,imaginal disc,heat sensitive,embryonic/larval brain,polytene chromosomeExel9043),ovary,female germline stem cell,embryonic/larval salivary gland,embryonic/larval central nervous system,mesothoracic tergum" DRSC03459 I 0.589767748 1.986121485 -0.956562385 -0.369826165 -1.008581182 -0.061813505 FBgn0039636 Atg14 Autophagy-related 14 http://flybase.net/reports/FBgn0039636.html protein_coding_gene "0010508=positive regulation of autophagy, 0010506=regulation of autophagy, 0006914=autophagy" "0034271=phosphatidylinositol 3-kinase complex, class III, type I" "CG11877, Autophagy-specific gene 14" IPR018791=UV radiation resistance protein/autophagy-related protein 14 CG11877 16-Dec-15 2015_12 ENSXETG00000015718(KIAA0831) ENSMUSG00000037526(Atg14) ENSG00000126775(ATG14) "viable,fertile" "embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0033412 CG13955 http://flybase.net/reports/FBgn0033412.html protein_coding_gene CG13955 16-Dec-15 2015_12 viable FBgn0263018 snRNA:U4atac:82E small nuclear RNA U4atac at 82E http://flybase.net/reports/FBgn0263018.html "FBgn0041718, FBgn0262950" snRNA_gene "0008380=RNA splicing, 0000398=mRNA splicing, via spliceosome" 0005690=U4atac snRNP "CR43269, U4atac, U4atac:cno-a, chr3R:1020715..1020926, CR32860, snRNA:U4atac:82E, U4atac-82E, snRNA_01" CR43269 16-Dec-15 2015_12 FBgn0065379 l(2)SH1671 lethal (2) SH1671 http://flybase.net/reports/FBgn0065379.html gene l(2)SH2 1671 16-Dec-15 2015_12 "lethal,recessive" FBgn0040396 CG3939 http://flybase.net/reports/FBgn0040396.html "FBgn0029650, FBgn0045765" protein_coding_gene "EG:140G11.5, BEST:SD07039" "IPR012336=Thioredoxin-like fold, IPR010357=Protein of unknown function DUF953, thioredoxin-like" CG3939 16-Dec-15 2015_12 WBGene00022188(Y71H2AR.1) viable FBgn0034400 CG15099 http://flybase.net/reports/FBgn0034400.html protein_coding_gene "IPR007249=Dopey, N-terminal" CG15099 16-Dec-15 2015_12 YDR141C(DOP1) WBGene00003905(pad-1) "ENSXETG00000022675(),ENSXETG00000014119(DOPEY2)" "ENSMUSG00000034973,ENSMUSG00000022946(Dopey2)" "ENSG00000142197(DOPEY2),ENSG00000083097(DOPEY1)" viable DRSC06528 K 0.637701493 0.163588789 1.422511617 0.004959979 -2.167634915 -0.421374931 FBgn0265912 CR44701 http://flybase.net/reports/FBgn0265912.html non_protein_coding_gene lincRNA.97 CR44701 16-Dec-15 2015_12 FBgn0065711 l(2)SH0591 lethal (2) SH0591 http://flybase.net/reports/FBgn0065711.html gene l(2)SH2 0591 16-Dec-15 2015_12 "lethal,recessive" FBgn0085751 CR40582 http://flybase.net/reports/FBgn0085751.html FBan0040582 rRNA_gene CR40582 16-Dec-15 2015_12 FBgn0058389 CG40389 http://flybase.net/reports/FBgn0058389.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267921 CR46202 http://flybase.net/reports/FBgn0267921.html non_protein_coding_gene lincRNA.227 CR46202 16-Dec-15 2015_12 FBgn0045759 bin biniou http://flybase.net/reports/FBgn0045759.html "FBgn0015501, FBgn0035728, FBtr0076900, FBpp0076609, FBtr0076901, FBpp0076610" protein_coding_gene "0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000976=transcription regulatory region sequence-specific DNA binding, 0008301=DNA binding, bending" "0051090=regulation of sequence-specific DNA binding transcription factor activity, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007389=pattern specification process, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007435=salivary gland morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0001710=mesodermal cell fate commitment" "0005634=nucleus, 0005667=transcription factor complex" "FoxF, Distal W5.4 Group XIV, FOXF, DmFoxF, binI, XIV, Biniou, BIN, CG18647, Bin, l(3)65CEe, Dmbin" "IPR001766=Fork head domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG18647 16-Dec-15 2015_12 "ENSDARG00000070389,ENSDARG00000017195,ENSDARG00000015399(foxf1)" YCR065W(HCM1) "ENSXETG00000003565(foxf1),ENSXETG00000000589(FOXF2)" "ENSMUSG00000038402(Foxf2),ENSMUSG00000042812(Foxf1a)" "ENSG00000137273(FOXF2),ENSG00000103241(FOXF1)" "lethal,cell migration defective,viable" "anterior embryonic/larval midgut,presumptive embryonic salivary gland,circular visceral muscle primordium,midgut constriction,longitudinal visceral muscle primordium,visceral mesoderm derivative,embryonic somatic muscle,embryonic pericardial cell" FBgn0267925 CR46206 http://flybase.net/reports/FBgn0267925.html non_protein_coding_gene lincRNA.123 CR46206 16-Dec-15 2015_12 FBgn0023112 anon-10Av anon-10Av http://flybase.net/reports/FBgn0023112.html gene 15 16-Dec-15 2015_12 FBgn0034565 CG15650 http://flybase.net/reports/FBgn0034565.html protein_coding_gene CG15650 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0023409 Ars-region46 Autonomous replicating sequence region 46 http://flybase.net/reports/FBgn0023409.html region "dARS46, Ars46" 16-Dec-15 2015_12 FBgn0029942 CG2059 http://flybase.net/reports/FBgn0029942.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG2059 16-Dec-15 2015_12 ENSDARG00000069501(abhd11) YGR031W() "WBGene00011029(R05D7.4),WBGene00009316(F32B4.6)" ENSXETG00000007793() ENSMUSG00000040532(Abhd11) ENSG00000106077(ABHD11) FBgn0000238 buo burnt orange http://flybase.net/reports/FBgn0000238.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0266152 CR44858 http://flybase.net/reports/FBgn0266152.html non_protein_coding_gene CR44858 16-Dec-15 2015_12 FBgn0267088 CR45532 http://flybase.net/reports/FBgn0267088.html non_protein_coding_gene CR45532 16-Dec-15 2015_12 FBgn0003373 Sgs3 Salivary gland secretion 3 http://flybase.net/reports/FBgn0003373.html protein_coding_gene "0005201=extracellular matrix structural constituent, 0005198=structural molecule activity" "0071390=cellular response to ecdysone, 0007594=puparial adhesion" "0031012=extracellular matrix, 0005576=extracellular region" "sgs3, Sgs-3, SGS-3, Muc68Cb, Gene IV, salivary gland glue protein 3, Sgs, CG11720, 68C GII, Glue, SGS378, sgs-3, DMSGS378, Mucin 68Cb, group IV" CG11720 16-Dec-15 2015_12 larval stage | third instar embryonic/larval salivary gland

larval stage | late third instar larval stage embryonic/larval salivary gland

electrophoretic variant FBgn0002661 mat(2)cell-J maternal effect cellularisation defect J http://flybase.net/reports/FBgn0002661.html gene 0007349=cellularization mat(2)cellRE43 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0037625 CG11768 http://flybase.net/reports/FBgn0037625.html protein_coding_gene CG11768 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0035257 CG12011 http://flybase.net/reports/FBgn0035257.html FBgn0025979 protein_coding_gene "clone 1.72, anon-EST:Liang-1.72" CG12011 16-Dec-15 2015_12 viable DRSC08219 K -0.32963451 -0.354516878 -0.780871222 -0.318181204 1.533812185 -0.083838661 FBgn0051859 CG31859 http://flybase.net/reports/FBgn0051859.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028984 Spn88Ea Serpin 88Ea http://flybase.net/reports/FBgn0028984.html FBgn0038298 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0030162=regulation of proteolysis, 0048526=imaginal disc-derived wing expansion, 0045861=negative regulation of proteolysis, 0010951=negative regulation of endopeptidase activity, 0045751=negative regulation of Toll signaling pathway" "0005615=extracellular space, 0005576=extracellular region" "Spn5, Spn88Ea, Sp5, spn5, Serine protease inhibitor 5, Dm-serpin-88Ea, sp5, CG18525, serpin5, serpin 5, serpin" "IPR000215=Serpin family, IPR023796=Serpin domain, IPR023795=Serpin, conserved site" CG18525 16-Dec-15 2015_12 "short lived,viable" wing FBgn0065741 l(2)SH0526 lethal (2) SH0526 http://flybase.net/reports/FBgn0065741.html gene l(2)SH2 0526 16-Dec-15 2015_12 "lethal,recessive" FBgn0040081 p88 p88 http://flybase.net/reports/FBgn0040081.html gene 16-Dec-15 2015_12 FBgn0038051 CG17207 http://flybase.net/reports/FBgn0038051.html FBgn0063740 protein_coding_gene 0016021=integral component of membrane BcDNA:AT11646 IPR002995=Surfeit locus 4 CG17207 16-Dec-15 2015_12 FBgn0035272 mRpL46 mitochondrial ribosomal protein L46 http://flybase.net/reports/FBgn0035272.html protein_coding_gene "0016787=hydrolase activity, 0003735=structural constituent of ribosome" 0032543=mitochondrial translation 0005762=mitochondrial large ribosomal subunit "MRP-L46, MRpL46, CG13922" "IPR015797=NUDIX hydrolase domain-like, IPR021757=Ribosomal protein L46, IPR000086=NUDIX hydrolase domain" CG13922 16-Dec-15 2015_12 ENSDARG00000016307(zgc:92810) YNL252C(MRPL17) ENSXETG00000007594(MRPL46) ENSMUSG00000030612(Mrpl46) ENSG00000173867(MRPL46) "viable,visible" trichogen cell DRSC08391 I -1.674590583 -1.322617881 -0.691824449 -1.236825347 0.810337925 -0.452405536 FBgn0036081 CG6559 http://flybase.net/reports/FBgn0036081.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0085691 CG41560 http://flybase.net/reports/FBgn0085691.html FBan0041560 protein_coding_gene 16-Dec-15 2015_12 FBgn0020818 l(3)98Dl lethal (3) 98Dl http://flybase.net/reports/FBgn0020818.html gene 16-Dec-15 2015_12 FBgn0038365 CG9593 http://flybase.net/reports/FBgn0038365.html protein_coding_gene "AAF55227, Fibrinogen-related protein, FBpp0082632" "IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1" CG9593 16-Dec-15 2015_12 WBGene00020516(T15B7.1) "ENSG00000116194(ANGPTL1),ENSG00000154188(ANGPT1),ENSG00000091879(ANGPT2),ENSG00000101280(ANGPT4),ENSG00000171564(FGB),ENSG00000187151(ANGPTL5)" viable FBgn0000500 Dsk Drosulfakinin http://flybase.net/reports/FBgn0000500.html "FBan0018090, FBgn0037214, FBgn0062936" protein_coding_gene "0005184=neuropeptide hormone activity, 0071855=neuropeptide receptor binding" "0007528=neuromuscular junction development, 0007204=positive regulation of cytosolic calcium ion concentration, 0008345=larval locomotory behavior, 0006940=regulation of smooth muscle contraction, 0033555=multicellular organismal response to stress, 0007218=neuropeptide signaling pathway, 0008344=adult locomotory behavior, 0008343=adult feeding behavior" 0005615=extracellular space "sulfakinin-0, DSK-2, DSK-I, Drosophila sulfakinin, DSK II, sulfakinin, BcDNA:RH46857, DrmSK-I, DrmSK-II, drosulfakinin, CG18090, Drososulfakinin, CCK, DSK I, DSK, Drm-SK-1, cholecystokinin-like, Drm-SK-0, Sulfakinin, DSK-1, SK-0, dsk, Drm-SK, Drm-SK-2, DSK-0" "IPR013152=Gastrin/cholecystokinin, conserved site" CG18090 16-Dec-15 2015_12 adult stage protocerebrum

"neuroanatomy defective,neurophysiology defective,stress response defective,locomotor behavior defective,viable,fertile" "embryonic/larval neuromuscular junction,NMJ bouton,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage" DRSC12347 K 1.205861528 -0.374293819 0.180803248 0.378568853 2.394881714 1.053449708 FBgn0264360 CR43812 http://flybase.net/reports/FBgn0264360.html non_protein_coding_gene CR43812 16-Dec-15 2015_12 FBgn0040055 CG14474 http://flybase.net/reports/FBgn0040055.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029507 Tsp42Ed Tetraspanin 42Ed http://flybase.net/reports/FBgn0029507.html FBgn0033125 protein_coding_gene 0016021=integral component of membrane "GH07074, BcDNA:GH07074, tetraspanin 42E, Dm.Tsp42Ed, CG12846" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin, IPR018503=Tetraspanin, conserved site" CG12846 16-Dec-15 2015_12 FBgn0032110 CG3748 http://flybase.net/reports/FBgn0032110.html "FBgn0044737, FBgn0061437" protein_coding_gene "anon-WO0140519.143, BcDNA:AT30262" IPR003887=LEM domain CG3748 16-Dec-15 2015_12 viable FBgn0038468 CG5225 http://flybase.net/reports/FBgn0038468.html protein_coding_gene IPR008160=Collagen triple helix repeat CG5225 16-Dec-15 2015_12 "viable,fertile" FBgn0085440 Lgr4 Leucine-rich repeat-containing G protein-coupled receptor 4 http://flybase.net/reports/FBgn0085440.html "FBgn0046558, FBgn0046550, FBgn0052637, FBgn0030458" protein_coding_gene "0016500=protein-hormone receptor activity, 0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.19, CG4187, DLGR4, dLGR4, CG32637, anon-WO0170980.20, Lgr4, CG34411" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR017452=GPCR, rhodopsin-like, 7TM, IPR008112=Relaxin receptor, IPR001611=Leucine-rich repeat" CG34411 16-Dec-15 2015_12 FBgn0010191 tu-So tu-So http://flybase.net/reports/FBgn0010191.html gene tu-So[c] 16-Dec-15 2015_12 partially lethal - majority die FBgn0041102 ocn ocnus http://flybase.net/reports/FBgn0041102.html FBgn0027614 protein_coding_gene 0005634=nucleus "Ocnus, CG7929, Ocn, BcDNA:GH02250, bs29e10.y1" IPR007702=Janus CG7929 16-Dec-15 2015_12 viable FBgn0001383 l(1)2Bo lethal (1) 2Bo http://flybase.net/reports/FBgn0001383.html gene 16-Dec-15 2015_12 lethal FBgn0037898 CG18643 http://flybase.net/reports/FBgn0037898.html protein_coding_gene "0016788=hydrolase activity, acting on ester bonds" 0019478=D-amino acid catabolic process 0005737=cytoplasm "IPR003732=D-aminoacyl-tRNA deacylase DTD, IPR023509=D-Tyr tRNAtyr deacylase-like domain" CG18643 16-Dec-15 2015_12 ENSDARG00000044628(hars2) YDL219W(DTD1) WBGene00004151(pqn-68) ENSXETG00000000790(DTD1) ENSMUSG00000027430(Dtd1) ENSG00000125821(DTD1) DRSC15362 K -0.244006956 0.259801922 0.215989131 0.328945131 0.227800281 1.566617609 FBgn0024342 KH2-9 KH domain cDNA KH2-9 http://flybase.net/reports/FBgn0024342.html gene unnamed 16-Dec-15 2015_12 FBgn0035888 CG7120 http://flybase.net/reports/FBgn0035888.html FBgn0063332 protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi7295100, BcDNA:AT15424" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG7120 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024883 l(2)04548 lethal (2) 04548 http://flybase.net/reports/FBgn0024883.html gene 16-Dec-15 2015_12 lethal FBgn0013618 l(3)L5150 lethal (3) L5150 http://flybase.net/reports/FBgn0013618.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037427 Osi17 Osiris 17 http://flybase.net/reports/FBgn0037427.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, mdcds_43703, CG15598" IPR012464=Protein of unknown function DUF1676 CG15598 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0003707 TipB Temperature-induced paralytic B http://flybase.net/reports/FBgn0003707.html gene 16-Dec-15 2015_12 "lethal,recessive,paralytic,heat sensitive" FBgn0020523 nerd nerd http://flybase.net/reports/FBgn0020523.html gene "0007617=mating behavior, 0042811=pheromone biosynthetic process" Nerd 16-Dec-15 2015_12 "mating defective,male,recessive" FBgn0013582 l(3)82Fj lethal (3) 82Fj http://flybase.net/reports/FBgn0013582.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041337 Cyp309a2 Cyp309a2 http://flybase.net/reports/FBgn0041337.html FBgn0031433 protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "Cytochrome P450 309a2, CG18559, 309a2" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG18559 16-Dec-15 2015_12 YHR007C(ERG11) viable FBgn0024643 l(2)k11326 lethal (2) k11326 http://flybase.net/reports/FBgn0024643.html gene 113/26 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0002562 Lsp1ë± Larval serum protein 1 ë± http://flybase.net/reports/FBgn0002562.html protein_coding_gene 0045735=nutrient reservoir activity "0005576=extracellular region, 0005811=lipid particle, 0005616=larval serum protein complex" "LSP-1alpha, LSP-1, LSP1-alpha, LSP 1, Lsp-1alpha, Lsp1, DmeLSP1a, Larval serum protein 1 alpha, Larval serum protein one alpha, Lsp1alpha, LSP1, Lsp1-alpha, LSP1alpha, LSP-1 alpha, CG2559, larval serum protein" "IPR005203=Hemocyanin, C-terminal, IPR005204=Hemocyanin, N-terminal, IPR013788=Hemocyanin/hexamerin, IPR008922=Uncharacterised domain, di-copper centre, IPR014756=Immunoglobulin E-set, IPR000896=Hemocyanin/hexamerin middle domain" CG2559 16-Dec-15 2015_12 " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

"electrophoretic variant,viable,fertile" egg DRSC25329 K 0.252334637 -0.125277535 -0.230797314 0.298288006 0.166907384 -2.559554076 FBgn0039027 CG7031 http://flybase.net/reports/FBgn0039027.html protein_coding_gene CG7031 16-Dec-15 2015_12 viable DRSC23028 K 1.844139299 1.48416253 FBgn0030936 CG6481 http://flybase.net/reports/FBgn0030936.html protein_coding_gene CG6481 16-Dec-15 2015_12 viable FBgn0040368 eIF4E-7 eIF4E-7 http://flybase.net/reports/FBgn0040368.html "FBgn0029559, FBgn0029560, FBgn0052859" protein_coding_gene "0000340=RNA 7-methylguanosine cap binding, 0031370=eukaryotic initiation factor 4G binding, 0003743=translation initiation factor activity, 0000339=RNA cap binding, 0005515=protein binding" 0006413=translational initiation 0016281=eukaryotic translation initiation factor 4F complex "CG32859, EG:BACR42I17.1, CT31794, eIF4E, CG11393, CG11392" "IPR019770=Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, IPR001040=Translation Initiation factor eIF- 4e, IPR023398=Translation Initiation factor eIF- 4e-like" CG32859 16-Dec-15 2015_12 "ENSDARG00000013274(zgc:101581),ENSDARG00000012274(zgc:110154),ENSDARG00000014565(eif4e1b)" YOL139C(CDC33) WBGene00002061(ife-3) "ENSXETG00000009316(eif4e),ENSXETG00000019631(EIF4E1B)" ENSMUSG00000028156(Eif4e) "ENSG00000151247(EIF4E),ENSG00000175766(EIF4E1B)" "viable,partially lethal - majority die,some die during pupal stage" FBgn0263770 CR43687 http://flybase.net/reports/FBgn0263770.html pseudogene_attribute CR43687 16-Dec-15 2015_12 FBgn0065445 l(2)SH1426 lethal (2) SH1426 http://flybase.net/reports/FBgn0065445.html gene l(2)SH2 1426 16-Dec-15 2015_12 "lethal,recessive" FBgn0014927 anon-72ABk anon-72ABk http://flybase.net/reports/FBgn0014927.html gene 16-Dec-15 2015_12 FBgn0266052 CR44817 http://flybase.net/reports/FBgn0266052.html non_protein_coding_gene CR44817 16-Dec-15 2015_12 FBgn0014881 Ssb-c15a Single stranded-binding protein c15a http://flybase.net/reports/FBgn0014881.html gene c15a 16-Dec-15 2015_12 FBgn0265911 CR44700 http://flybase.net/reports/FBgn0265911.html non_protein_coding_gene CR44700 16-Dec-15 2015_12 FBgn0070039 3R-64-22 3R-64-22 http://flybase.net/reports/FBgn0070039.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0265308 CR44281 http://flybase.net/reports/FBgn0265308.html non_protein_coding_gene CR44281 16-Dec-15 2015_12 FBgn0264899 CG44090 http://flybase.net/reports/FBgn0264899.html protein_coding_gene CG44090 16-Dec-15 2015_12 FBgn0037202 Ssl1 Suppressor of Stem-Loop mutation ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0037202.html protein_coding_gene "0008270=zinc ion binding, 0000990=core RNA polymerase binding transcription factor activity" "0001111=promoter clearance from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0001113=transcriptional open complex formation at RNA polymerase II promoter, 0006289=nucleotide-excision repair" "0000439=core TFIIH complex, 0005675=holo TFIIH complex, 0005634=nucleus" "ssl1, CG11115, p44, SSL1, Ssl1" "IPR007198=Ssl1-like, IPR012170=TFIIH subunit Ssl1/p44, IPR002035=von Willebrand factor, type A, IPR007087=Zinc finger, C2H2, IPR004595=TFIIH C1-like domain" CG11115 16-Dec-15 2015_12 ENSDARG00000016514(gtf2h2) YLR005W(SSL1) WBGene00011814(T16H12.4) ENSXETG00000026187() ENSMUSG00000021639(Gtf2h2) "ENSG00000145736(GTF2H2),ENSG00000183474(GTF2H2C)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262290 mir-iab-8 mir-iab-8 stem loop http://flybase.net/reports/FBgn0262290.html miRNA_gene "iab-8, mir-iab8, mir-iab-4as-5p, iab-8 miRNA, CR42997, dme-iab-8, MIR-iab-4as, mir-iab-4as, dme-mir-iab-8, miR-iab-8, miR-iab-4as, miR-iab-8-5p, miR-iab-4AS, iab-8 microRNA" CR42997 16-Dec-15 2015_12 "visible,homeotic,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "wing,ectopic,haltere" FBgn0000814 fs(1)K254 female sterile (1) K254 http://flybase.net/reports/FBgn0000814.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile soma-dependent,female sterile,recessive,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "dorsal appendage,chorion" FBgn0053766 CG33766 http://flybase.net/reports/FBgn0053766.html FBgn0037173 protein_coding_gene CG14458 IPR010512=Protein of unknown function DUF1091 CG33766 16-Dec-15 2015_12 DRSC11717 E 0.911471654 -0.036711042 2.562516219 0.920692551 -0.005139367 0.971594994 FBgn0267641 CR45979 http://flybase.net/reports/FBgn0267641.html non_protein_coding_gene CR45979 16-Dec-15 2015_12 FBgn0260494 boa baobab http://flybase.net/reports/FBgn0260494.html gene 0007409=axonogenesis 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,axon" FBgn0004072 fs(2)mel6 female sterile (2) maternal effect lethal 6 http://flybase.net/reports/FBgn0004072.html gene Mel 6 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,semidominant,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,embryonic head" FBgn0052269 CG32269 http://flybase.net/reports/FBgn0052269.html "FBgn0035419, FBgn0053161, FBtr0073100, FBpp0072962, FBtr0073101, FBpp0072963" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG11530, CG33161, SP124" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG32269 16-Dec-15 2015_12 FBgn0044382 T:SS-ea Signal sequence of ea http://flybase.net/reports/FBgn0044382.html engineered_tag "easter signal sequence, T:ea" 16-Dec-15 2015_12 FBgn0052734 CG32734 http://flybase.net/reports/FBgn0052734.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003863 ë±Try ë±Trypsin http://flybase.net/reports/FBgn0003863.html FBgn0033621 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "SP102, alpha, CG18444, Try, alphaTry, DmAlphaTry" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG18444 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" " larval stage | third instar , adult stage " larval digestive system | restricted

FBgn0036266 CG5626 http://flybase.net/reports/FBgn0036266.html protein_coding_gene 0004017=adenylate kinase activity "IPR024337=tRNA-splicing endonuclease, subunit Sen54, IPR024336=tRNA-splicing endonuclease, subunit Sen54, N-terminal" CG5626 16-Dec-15 2015_12 viable FBgn0037265 spartin spartin http://flybase.net/reports/FBgn0037265.html protein_coding_gene "0030514=negative regulation of BMP signaling pathway, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0007274=neuromuscular synaptic transmission" "0005886=plasma membrane, 0005769=early endosome, 0043195=terminal bouton, 0042734=presynaptic membrane" CG12001 "IPR009686=Senescence/spartin-associated, IPR007330=MIT" CG12001 16-Dec-15 2015_12 WBGene00019006(F57B10.9) ENSMUSG00000036580(Spg20) ENSG00000133104(SPG20) "viable,fertile,neuroanatomy defective,neurophysiology defective,locomotor behavior defective,progressive" "NMJ bouton,supernumerary,adult brain,progressive,supernumerary | third instar larval stage" FBgn0270926 AsnS Asparagine synthetase http://flybase.net/reports/FBgn0270926.html "FBgn0024505, FBgn0053486, FBgn0041607" protein_coding_gene "0004066=asparagine synthase (glutamine-hydrolyzing) activity, 0004071=aspartate-ammonia ligase activity" 0006529=asparagine biosynthetic process "CG33486, AS, asparagine-synthetase, asparagine synthetase" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR017932=Glutamine amidotransferase type 2 domain, IPR006426=Asparagine synthase, glutamine-hydrolyzing, IPR001962=Asparagine synthase" CG33486 16-Dec-15 2015_12 ENSDARG00000016375(asns) "YPR145W(ASN1),YGR124W(ASN2)" WBGene00019730(M02D8.4) ENSXETG00000025707(asns) ENSMUSG00000029752(Asns) ENSG00000070669(ASNS) FBgn0030763 CG9782 http://flybase.net/reports/FBgn0030763.html protein_coding_gene CG9782 16-Dec-15 2015_12 viable FBgn0082952 snoRNA:Me18S-A1061 snoRNA:Me18S-A1061 http://flybase.net/reports/FBgn0082952.html snoRNA_gene "Me18S-A1061 (DmSnR54), CR34537, Me18S-Am1061, Dm_18S.001, DmSnR54" CR34537 16-Dec-15 2015_12 FBgn0035371 CG9977 http://flybase.net/reports/FBgn0035371.html protein_coding_gene 0004013=adenosylhomocysteinase activity 0006730=one-carbon metabolic process "IPR020082=S-adenosyl-L-homocysteine hydrolase, conserved site, IPR000043=Adenosylhomocysteinase, IPR015878=S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR016040=NAD(P)-binding domain" CG9977 16-Dec-15 2015_12 "ENSDARG00000039343(ahcyl2),ENSDARG00000056331(ahcyl1),ENSDARG00000051873(zgc:158222)" "ENSXETG00000002023(AHCYL1),ENSXETG00000014902(BC090609.1)" "ENSMUSG00000029772(Ahcyl2),ENSMUSG00000027893(Ahcyl1)" "ENSG00000158467(AHCYL2),ENSG00000168710(AHCYL1)" viable FBgn0060328 l(3)S146411b lethal (3) S146411b http://flybase.net/reports/FBgn0060328.html gene 1464/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0259309 EP-476 http://flybase.net/reports/FBgn0259309.html gene 16-Dec-15 2015_12 visible "wing,wing margin" FBgn0034182 CG9640 http://flybase.net/reports/FBgn0034182.html protein_coding_gene IPR001214=SET domain CG9640 16-Dec-15 2015_12 viable FBgn0034266 CG4975 http://flybase.net/reports/FBgn0034266.html protein_coding_gene 0005737=cytoplasm "IPR019156=Ataxin-10 domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG4975 16-Dec-15 2015_12 ENSMUSG00000016541(Atxn10) ENSG00000130638(ATXN10) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0260297 GSd232 http://flybase.net/reports/FBgn0260297.html gene 16-Dec-15 2015_12 lethal FBgn0259822 Ca-ë_ Ca2+-channel-protein-ë_-subunit http://flybase.net/reports/FBgn0259822.html "FBgn0015608, FBgn0032353, FBgn0032351, FBgn0032352, FBgn0053305" protein_coding_gene 0005245=voltage-gated calcium channel activity "0006816=calcium ion transport, 0070588=calcium ion transmembrane transport" "0005891=voltage-gated calcium channel complex, 0005886=plasma membrane" "CG14922, Ca-beta, DmCa1beta, CG33305, Ca2+-channel-protein beta subunit, CG6320, CG14923, CG42403, calcium channel beta subunit, ca-beta, Calcium channel beta, CaBeta, Ca[2+]-channel-protein-beta-subunit, Ca2+-channel-protein-beta-subunit, dmcab1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR001452=SH3 domain, IPR000584=Voltage-dependent calcium channel, L-type, beta subunit" CG42403 16-Dec-15 2015_12 "ENSDARG00000009738(cacnb4a),ENSDARG00000062174(cacnb4b),ENSDARG00000034352,ENSDARG00000001881(cacnb3a),ENSDARG00000039135,ENSDARG00000002167(cacnb1)" ENSXETG00000022755(CACNB2) "ENSMUSG00000017412(Cacnb4),ENSMUSG00000057914(Cacnb2),ENSMUSG00000020882(Cacnb1),ENSMUSG00000003352(Cacnb3)" "ENSG00000165995(CACNB2),ENSG00000067191(CACNB1),ENSG00000182389(CACNB4)" DRSC03285 K 0.223235351 0.633243612 0.09161656 0.198400026 -1.625386545 -0.251280382 FBgn0263081 CG43349 http://flybase.net/reports/FBgn0263081.html protein_coding_gene CG43349 16-Dec-15 2015_12 FBgn0040566 CG14328 http://flybase.net/reports/FBgn0040566.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039290 CG13654 http://flybase.net/reports/FBgn0039290.html protein_coding_gene "IPR013032=EGF-like, conserved site, IPR021910=Protein of unknown function DUF3522, IPR000742=EGF-like domain" CG13654 16-Dec-15 2015_12 "ENSXETG00000009858(),ENSXETG00000012131(TMEM8A)" "ENSMUSG00000078716,ENSMUSG00000024180(Tmem8)" "ENSG00000129925(TMEM8A),ENSG00000137103(TMEM8B)" viable FBgn0044046 Ilp7 Insulin-like peptide 7 http://flybase.net/reports/FBgn0044046.html FBgn0029673 protein_coding_gene "0005179=hormone activity, 0005158=insulin receptor binding" 0008286=insulin receptor signaling pathway 0005615=extracellular space "Ilp7, Ilp-7, Dilp7, Ilp, insulin-like peptide 7, dilp7, DILP-7, dilp, dILP8, dilp-7, Dilp, CG13317, dILP7, Drosophila insulin-like peptide 7, Dilp 7, ilp7, DILP, insulin-like peptide, ILP7, DILP7" IPR016179=Insulin-like CG13317 16-Dec-15 2015_12 " embryonic stage , larval stage | third instar " " organism

, ventral nerve cord | restricted & segmentally repeated

" "large body,behavior defective,female,viable" FBgn0040777 CG14767 http://flybase.net/reports/FBgn0040777.html FBgn0033329 protein_coding_gene 0015205=nucleobase transmembrane transporter activity "0005765=lysosomal membrane, 0016021=integral component of membrane" "dmCG14767, CG8575" "IPR004687=Lysosomal-associated transmembrane protein 4/5, IPR018400=Tetraspanning orphan receptor" CG14767 16-Dec-15 2015_12 "ENSDARG00000006397(LOC100332342),ENSDARG00000035870(laptm4b)" ENSXETG00000008012(LAPTM4A) "ENSMUSG00000020585(Laptm4a),ENSMUSG00000022257(Laptm4b)" "ENSG00000068697(LAPTM4A),ENSG00000104341(LAPTM4B)" "viable,fertile" FBgn0264644 etiolated etiolated http://flybase.net/reports/FBgn0264644.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "embryonic/larval tracheal system,eye,somatic clone" FBgn0027844 CAH1 Carbonic anhydrase 1 http://flybase.net/reports/FBgn0027844.html FBgn0027926 protein_coding_gene "0004089=carbonate dehydratase activity, 0008270=zinc ion binding" 0006730=one-carbon metabolic process 0005737=cytoplasm "CAH, CG7820, BG:DS00941.1, Gh7" "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class, IPR018338=Carbonic anhydrase, alpha-class, conserved site" CG7820 16-Dec-15 2015_12 "ENSDARG00000011166(cahz),ENSDARG00000071471,ENSDARG00000014488(ca2),ENSDARG00000067684,ENSDARG00000045139(ca7)" WBGene00000282(cah-4) "ENSXETG00000013740(ca2),ENSXETG00000026010(CA13),ENSXETG00000013747(CA1),ENSXETG00000013774(CA3),ENSXETG00000016594(ca5b),ENSXETG00000017420(ca7)" "ENSMUSG00000027562(Car2),ENSMUSG00000027559(Car3),ENSMUSG00000027556(Car1),ENSMUSG00000027555(Car13),ENSMUSG00000031883(Car7),ENSMUSG00000031373(Car5b),ENSMUSG00000025317(Car5a)" "ENSG00000168748(CA7),ENSG00000104267(CA2),ENSG00000185015(CA13),ENSG00000133742(CA1),ENSG00000164879(CA3),ENSG00000169239(CA5B),ENSG00000174990(CA5A)" FBgn0063083 pncr015:3L putative noncoding RNA 015:3L http://flybase.net/reports/FBgn0063083.html FBgn0053948 non_protein_coding_gene "CR33948, BcDNA:LP12023" CR33948 16-Dec-15 2015_12 FBgn0033884 CG13344 http://flybase.net/reports/FBgn0033884.html FBgn0025332 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination "anon-EST:GreesD1, anon-EST:GressD1" "IPR001841=Zinc finger, RING-type, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR006575=RWD domain" CG13344 16-Dec-15 2015_12 ENSDARG00000027182(zgc:66260) WBGene00021812(Y53G8AR.5) ENSXETG00000018815(rnf25) ENSMUSG00000026171(Rnf25) ENSG00000163481(RNF25) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0001539 l(1)14DEa lethal (1) 14DEa http://flybase.net/reports/FBgn0001539.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020387 Pdz Pdz http://flybase.net/reports/FBgn0020387.html gene "0005912=adherens junction, 0005918=septate junction" 16-Dec-15 2015_12 FBgn0263107 bft bereft http://flybase.net/reports/FBgn0263107.html "FBgn0041606, FBgn0051863, FBgn0262399, FBgn0067722, FBgn0262231" miRNA_gene "0035195=gene silencing by miRNA, 0022416=chaeta development, 0043066=negative regulation of apoptotic process, 0001745=compound eye morphogenesis, 0008407=chaeta morphogenesis" "miR-263a, CR31863, CR42938, 263a, miR-263, mir-263a stem loop, dme-miR-263a, dme-mir-263a, CR33580, mir-263a" CR42938 16-Dec-15 2015_12 "lethal,partially,viable,recessive,visible,lethal - all die before end of P-stage,some die during pharate adult stage,fertile" "interommatidial bristle,orbital bristle,vertical bristle,postvertical bristle,humeral bristle,dorsocentral bristle,postalar bristle,scutellar bristle,eye,wing,wing margin bristle,interommatidial bristle & socket,sensillum trichodeum,sensillum trichodeum & trichogen cell" FBgn0065335 l(2)SH1856 lethal (2) SH1856 http://flybase.net/reports/FBgn0065335.html gene l(2)SH2 1856 16-Dec-15 2015_12 "lethal,recessive" FBgn0084678 vto vertigo http://flybase.net/reports/FBgn0084678.html gene 0008344=adult locomotory behavior O151 16-Dec-15 2015_12 "locomotor behavior defective,recessive" FBgn0035610 Lkr Leucokinin receptor http://flybase.net/reports/FBgn0035610.html "FBgn0044363, FBgn0046609, FBgn0046610" protein_coding_gene "0004983=neuropeptide Y receptor activity, 0008188=neuropeptide receptor activity, 0042071=leucokinin receptor activity" "0007204=positive regulation of cytosolic calcium ion concentration, 2000252=negative regulation of feeding behavior, 0007186=G-protein coupled receptor signaling pathway" "0016323=basolateral plasma membrane, 0016021=integral component of membrane" "LkR, lkr, anon-WO0170980.119, LKR, anon-WO0131005.17, Kinin receptor, leucokinin receptor, DLKR, dLKR, CG10626, anon-WO0170980.118, Drosokinin receptor, LK-R" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR000611=Neuropeptide Y receptor family, IPR017452=GPCR, rhodopsin-like, 7TM" CG10626 16-Dec-15 2015_12 "ENSDARG00000062631(gpr74),ENSDARG00000010712(npffr1l3),ENSDARG00000054203(LOC559950)" WBGene00006428(tag-49) "ENSXETG00000006144(NPFFR1),ENSXETG00000008127(NPFFR2)" viable FBgn0266735 CR45208 http://flybase.net/reports/FBgn0266735.html non_protein_coding_gene CR45208 16-Dec-15 2015_12 FBgn0017483 Sxl::w Sxl::w http://flybase.net/reports/FBgn0017483.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0002927 Ndw Nicked wing http://flybase.net/reports/FBgn0002927.html gene 16-Dec-15 2015_12 "visible,dominant,cold sensitive,lethal,recessive" FBgn0085324 CG34295 http://flybase.net/reports/FBgn0085324.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG34295 16-Dec-15 2015_12 FBgn0267117 CR45557 http://flybase.net/reports/FBgn0267117.html non_protein_coding_gene CR45557 16-Dec-15 2015_12 FBgn0020795 oculus-parvus oculus parvus http://flybase.net/reports/FBgn0020795.html gene opa 16-Dec-15 2015_12 eye FBgn0004965 coq coquilled http://flybase.net/reports/FBgn0004965.html gene 0008587=imaginal disc-derived wing margin morphogenesis 16-Dec-15 2015_12 "lethal,recessive,maternal effect,some die during immature adult stage" "wing,ovary,maternal effect,egg" FBgn0259821 CG42402 http://flybase.net/reports/FBgn0259821.html "FBan0012453, FBgn0039950, FBan0041358, FBgn0085630, CG12453, CG41358" protein_coding_gene 0030246=carbohydrate binding "CG41358, CG12453" IPR000922=D-galactoside/L-rhamnose binding SUEL lectin domain CG42402 16-Dec-15 2015_12 viable FBgn0086303 proj projectile http://flybase.net/reports/FBgn0086303.html gene 0046847=filopodium assembly 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0266101 CG44838 http://flybase.net/reports/FBgn0266101.html "FBgn0052043, FBgn0036001, FBgn0036002, FBgn0062015, FBgn0062063, FBgn0036003" protein_coding_gene "anon-WO0118547.427, anon-WO0118547.368, CG32043, CG18632, rugose, CG14180, CG3628" CG44838 16-Dec-15 2015_12 DRSC10179 EK -0.71726897 -1.492336756 0.314343695 -1.558680022 1.658581272 0.790585339 FBgn0266486 CG45085 http://flybase.net/reports/FBgn0266486.html protein_coding_gene Dromel_CG8026_FBtr0088611_uORF CG45085 16-Dec-15 2015_12 FBgn0034114 CG4282 http://flybase.net/reports/FBgn0034114.html protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR017956=AT hook, DNA-binding motif, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG4282 16-Dec-15 2015_12 viable FBgn0032331 CG14913 http://flybase.net/reports/FBgn0032331.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG14913 16-Dec-15 2015_12 viable FBgn0011865 tRNA:G3:35Bd transfer RNA:gly3:35Bd http://flybase.net/reports/FBgn0011865.html "FBgn0003779, FBgn0051981, FBgn0060221" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033462=GGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002690.trna16-GlyGCC, tRNA:G:GCC:AE002690-d, BG:DS04641.6, CR31981, chr2L.trna25-GlyGCC, tRNA:gly3:35Bd, tRNA[Gly-GCC]" CR31981 16-Dec-15 2015_12 FBgn0001570 l(1)20Cb lethal (1) 20Cb http://flybase.net/reports/FBgn0001570.html gene "l(1)20, lQ463, l(1)Q463, l20, 20, unnamed, Q463" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,polyphasic" FBgn0265741 CR44548 http://flybase.net/reports/FBgn0265741.html non_protein_coding_gene lincRNA.515 CR44548 16-Dec-15 2015_12 FBgn0030480 Tim9a Tim9a http://flybase.net/reports/FBgn0030480.html protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0015031=protein transport, 0006626=protein targeting to mitochondrion" 0005744=mitochondrial inner membrane presequence translocase complex "Tim9, CG1660" IPR004217=Tim10/DDP family zinc finger CG1660 16-Dec-15 2015_12 ENSDARG00000043865(timm9) YEL020W-A(TIM9) WBGene00006572(tin-9.1) ENSXETG00000026270(TIMM9) ENSMUSG00000021079(Timm9) ENSG00000100575(TIMM9) "lethal,recessive,viable" FBgn0001729 l(1)ESHS50 lethal (1) ESHS50 http://flybase.net/reports/FBgn0001729.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065976 iab4-5.as iab4-5.as http://flybase.net/reports/FBgn0065976.html gene 4-5 as 16-Dec-15 2015_12 FBgn0053929 CR33929 http://flybase.net/reports/FBgn0053929.html pseudogene_attribute CG33929 CR33929 16-Dec-15 2015_12 FBgn0065803 l(2)SH0400 lethal (2) SH0400 http://flybase.net/reports/FBgn0065803.html gene l(2)SH2 0400 16-Dec-15 2015_12 "lethal,recessive" FBgn0036950 CG6996 http://flybase.net/reports/FBgn0036950.html protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG6996 16-Dec-15 2015_12 viable FBgn0000584 Erect Erect http://flybase.net/reports/FBgn0000584.html gene Er 16-Dec-15 2015_12 visible "posterior scutellar bristle,wing" FBgn0038857 Bdbt Bride of doubletime http://flybase.net/reports/FBgn0038857.html protein_coding_gene 0005515=protein binding "0042176=regulation of protein catabolic process, 1901873=regulation of post-translational protein modification, 0045475=locomotor rhythm" 0005829=cytosol "bride of dbt, BRIDE OF DOUBLETIME, bdbt, CG17282" "IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR011990=Tetratricopeptide-like helical domain" CG17282 16-Dec-15 2015_12 "viable,visible,locomotor rhythm defective" "trichogen cell,supernumerary,tormogen cell,mesothoracic tergum" DRSC15218 E 0.306965522 -0.261764955 1.643426628 0.387140507 0.427029056 0.388126594 FBgn0069960 CG41053 http://flybase.net/reports/FBgn0069960.html FBan0041053 protein_coding_gene 16-Dec-15 2015_12 FBgn0262720 CG43164 http://flybase.net/reports/FBgn0262720.html "FBgn0061355, FBgn0034227, FBgn0053006, FBtr0086930, FBpp0086086, FBtr0086931, FBpp0086087, FBtr0086932, FBpp0086088, FBgn0061354, FBgn0022342" protein_coding_gene "anon-EST:fe2D7, anon-fast-evolving-2D7, CG33006, unnamed, CG4844b, CG18431, CG4844, CG4844a, anon2D7" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG43164 16-Dec-15 2015_12 DRSC06896 K -0.95973403 -0.697151696 -0.336705308 1.314712154 2.231660242 0.931839492 FBgn0005286 mei-S51 meiotic from via Salaria 51 http://flybase.net/reports/FBgn0005286.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "meiotic cell cycle defective,female" FBgn0082997 snoRNA:ë¬28S-1232 snoRNA:ë¬28S-1232 http://flybase.net/reports/FBgn0082997.html snoRNA_gene "CR34592, Psi 28S-1232, psi-28S-1232, Psi28S-1232, psi28S-1232" CR34592 16-Dec-15 2015_12 FBgn0263863 mRpL45 mitochondrial ribosomal protein L45 http://flybase.net/reports/FBgn0263863.html "FBgn0038996, FBgn0004709, FBgn0002501" protein_coding_gene 0003735=structural constituent of ribosome 0005762=mitochondrial large ribosomal subunit "l(3)A8, l(3)SG61, mitochondrial ribosomal protein large subunit 45, CG6949, l(3)dsl-8, l(3)dsl8, XI-2, lethal (3) SG61, MRP-L45" IPR007379=Tim44-like domain CG6949 16-Dec-15 2015_12 ENSDARG00000044942(mrpl45) WBGene00022493(Y119D3B.16) ENSXETG00000014731() ENSMUSG00000018882(Mrpl45) ENSG00000174100(MRPL45) DRSC16146 E -0.2764334 0.171994131 -1.573378247 -0.246093997 -0.268290492 0.071577735 FBgn0259622 B0066 http://flybase.net/reports/FBgn0259622.html gene 16-Dec-15 2015_12 visible wing vein FBgn0264816 koko kokopelli http://flybase.net/reports/FBgn0264816.html "FBgn0051232, FBgn0038618, FBgn0264752" protein_coding_gene 0019901=protein kinase binding "0006355=regulation of transcription, DNA-templated, 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0007179=transforming growth factor beta receptor signaling pathway, 0048133=male germ-line stem cell asymmetric division" "Kokopelli, CG44010, CG7683, CG31232" "IPR013763=Cyclin-like, IPR015429=Cyclin C/H/T/L, IPR006671=Cyclin, N-terminal, IPR028759=Cyclin-related protein FAM58" CG44010 16-Dec-15 2015_12 "viable,fertile" FBgn0030970 CG7326 http://flybase.net/reports/FBgn0030970.html protein_coding_gene IPR019193=Ubiquitin-conjugating enzyme E2-binding protein CG7326 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0003152 Pigmentless Pigmentless http://flybase.net/reports/FBgn0003152.html gene Ps 16-Dec-15 2015_12 "lethal,recessive,body color defective,dominant,female limited" adult abdomen & cuticle | female FBgn0262780 Su(E1)-N http://flybase.net/reports/FBgn0262780.html gene 16-Dec-15 2015_12 FBgn0013260 E(var)48 E(var)48 http://flybase.net/reports/FBgn0013260.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0039226 Ude Uracil-DNA degrading factor http://flybase.net/reports/FBgn0039226.html protein_coding_gene "0003677=DNA binding, 0032296=double-stranded RNA-specific ribonuclease activity, 0003723=RNA binding, 0004844=uracil DNA N-glycosylase activity" "0035074=pupation, 0006308=DNA catabolic process" "uracil-DNA-degrading factor, uracil-DNA degrading factor, UDE, CG18410" CG18410 16-Dec-15 2015_12 "viable,fertile" FBgn0004007 we wee http://flybase.net/reports/FBgn0004007.html gene 16-Dec-15 2015_12 "fertile,poor,small body" "eye,macrochaeta,wing" FBgn0053458 CG33458 http://flybase.net/reports/FBgn0053458.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG33458 16-Dec-15 2015_12 viable FBgn0014197 l(1)14Cd lethal (1) 14Cd http://flybase.net/reports/FBgn0014197.html gene l(1)14Ce 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone" FBgn0065197 l(2)SH2320 lethal (2) SH2320 http://flybase.net/reports/FBgn0065197.html gene l(2)SH2 2320 16-Dec-15 2015_12 "lethal,recessive" FBgn0266505 s-334 http://flybase.net/reports/FBgn0266505.html gene 16-Dec-15 2015_12 FBgn0082632 S(CycEJP)2.6 S(CycEJP)2.6 http://flybase.net/reports/FBgn0082632.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264821 CR44029 http://flybase.net/reports/FBgn0264821.html non_protein_coding_gene CR44029 16-Dec-15 2015_12 FBgn0082617 S(CycEJP)68S10 S(CycEJP)68S10 http://flybase.net/reports/FBgn0082617.html gene 68S10 16-Dec-15 2015_12 "lethal,recessive" FBgn0083305 E(smoDN)1551 Enhancer of smoDN 1551 http://flybase.net/reports/FBgn0083305.html gene 16-Dec-15 2015_12 FBgn0023134 WppI White prepupal locus I http://flybase.net/reports/FBgn0023134.html gene "37, 10, 22A" 16-Dec-15 2015_12 FBgn0262970 CR43281 http://flybase.net/reports/FBgn0262970.html pseudogene_attribute CR43281 16-Dec-15 2015_12 FBgn0028176 l(3)S026115b lethal (3) S026115b http://flybase.net/reports/FBgn0028176.html gene "0261/15, l(3)S026115" 16-Dec-15 2015_12 "lethal,recessive" FBgn0063398 Stalker2\ORF1 ORF1 http://flybase.net/reports/FBgn0063398.html transposable_element_gene rom\ORF1 16-Dec-15 2015_12 FBgn0040082 p82 p82 http://flybase.net/reports/FBgn0040082.html gene 16-Dec-15 2015_12 FBgn0052666 Drak Death-associated protein kinase related http://flybase.net/reports/FBgn0052666.html "FBgn0030308, FBgn0040853, FBgn0062687" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0007480=imaginal disc-derived leg morphogenesis, 0040018=positive regulation of multicellular organism growth, 0007155=cell adhesion, 0007476=imaginal disc-derived wing morphogenesis, 0008360=regulation of cell shape, 0006468=protein phosphorylation, 0002009=morphogenesis of an epithelium" "EP(X)1452, EP1452, drak, CG32666, CG11713, CG1760" "IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain" CG32666 16-Dec-15 2015_12 "YDR490C(PKH1),YOL100W(PKH2)" WBGene00013869(ZC373.4) "viable,fertile,visible,lethal" "wing,metathoracic leg,chaeta,supernumerary" FBgn0260044 33R6 http://flybase.net/reports/FBgn0260044.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0000707 fltM flight defective M http://flybase.net/reports/FBgn0000707.html gene 16-Dec-15 2015_12 flight defective FBgn0023045 l(1)3Bg lethal (1) 3Bg http://flybase.net/reports/FBgn0023045.html gene B2/50.8 16-Dec-15 2015_12 "lethal,recessive" FBgn0035911 CG6638 http://flybase.net/reports/FBgn0035911.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0008470=isovaleryl-CoA dehydrogenase activity" "0006552=leucine catabolic process, 0055114=oxidation-reduction process" 0005759=mitochondrial matrix "IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR006089=Acyl-CoA dehydrogenase, conserved site, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal" CG6638 16-Dec-15 2015_12 ENSDARG00000042853(ivd) WBGene00015326(ivd-1) ENSXETG00000016078(ivd) ENSMUSG00000027332(Ivd) ENSG00000128928(IVD) FBgn0004679 Esm Enhancer of split mimic http://flybase.net/reports/FBgn0004679.html gene 16-Dec-15 2015_12 FBgn0028839 C5 C5 http://flybase.net/reports/FBgn0028839.html gene 16-Dec-15 2015_12 "locomotor behavior defective,dominant,viable" FBgn0053451 5SrRNA:CR33451 5SrRNA:CR33451 http://flybase.net/reports/FBgn0053451.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33451 CR33451 16-Dec-15 2015_12 FBgn0266580 Gp210 Gp210 ortholog (H. sapiens) http://flybase.net/reports/FBgn0266580.html "FBgn0033039, FBgn0040848, FBgn0019983" protein_coding_gene "0006999=nuclear pore organization, 0008355=olfactory learning, 0006606=protein import into nucleus, 0007611=learning or memory" "0016021=integral component of membrane, 0070762=nuclear pore transmembrane ring, 0005643=nuclear pore, 0044611=nuclear pore inner ring, 0005737=cytoplasm, 0044615=nuclear pore nuclear basket" "gp210, gp188, CG7897, gp210[[D]], CG14467, GP210, Gp188, lyadi, Dm gp210" IPR008964=Invasin/intimin cell-adhesion fragments CG7897 16-Dec-15 2015_12 WBGene00003798(npp-12) "ENSMUSG00000030091(Nup210),ENSMUSG00000027939(Nup210l)" "ENSG00000132182(NUP210),ENSG00000143552(NUP210L)" embryonic stage | early FBgn0265200 CR44260 http://flybase.net/reports/FBgn0265200.html non_protein_coding_gene lincRNA.714 CR44260 16-Dec-15 2015_12 FBgn0000305 ch-b chilblained b http://flybase.net/reports/FBgn0000305.html gene 16-Dec-15 2015_12 "visible,recessive" tarsal segment FBgn0003203 rar3 radiation-resistant on 3 http://flybase.net/reports/FBgn0003203.html gene 16-Dec-15 2015_12 FBgn0021912 l(2)k11502 lethal (2) k11502 http://flybase.net/reports/FBgn0021912.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260094 2L1923 http://flybase.net/reports/FBgn0260094.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0014300 l(3)7-19 lethal (3) 7-19 http://flybase.net/reports/FBgn0014300.html gene 16-Dec-15 2015_12 "lethal,recessive" macrochaeta FBgn0020782 skarped-wing skarped wing http://flybase.net/reports/FBgn0020782.html gene 16-Dec-15 2015_12 "visible,viable,fertile" wing FBgn0260985 RfC4 Replication factor C subunit 4 http://flybase.net/reports/FBgn0260985.html "FBgn0026776, FBgn0002460, FBgn0004708, FBgn0015287, FBgn0043808" protein_coding_gene "0003677=DNA binding, 0004003=ATP-dependent DNA helicase activity, 0005524=ATP binding" "0000076=DNA replication checkpoint, 0000077=DNA damage checkpoint, 0006271=DNA strand elongation involved in DNA replication, 0022008=neurogenesis, 0007076=mitotic chromosome condensation, 0007067=mitotic nuclear division, 0006260=DNA replication, 0016321=female meiosis chromosome segregation, 0046331=lateral inhibition, 0006281=DNA repair, 0000819=sister chromatid segregation" "0005875=microtubule associated complex, 0005663=DNA replication factor C complex, 0005634=nucleus" "l(3)dsl-1, l(3)e20, l(3)A1, l(3)64Ai, 154910_at, lethal (3) SG13, rfc4, l(3)Rfc4, rfc40, rfc[40], Rfc40, Rfc4, Replication-factor-C 40kD subunit, RfC40, CG14999, l(3)dsl1, RFC40, l(3)rfc40, l(3)SG13, DmRFC4, BEST:GH24992, l(3)SH17, rfc" "IPR013748=Replication factor C, C-terminal, IPR003593=AAA+ ATPase domain, IPR008921=DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG14999 16-Dec-15 2015_12 ENSDARG00000014274(rfc2) YOL094C(RFC4) WBGene00004338(rfc-2) ENSXETG00000018234(RFC2) ENSMUSG00000023104(Rfc2) ENSG00000049541(RFC2) embryonic stage FBgn0067319 CG40450 http://flybase.net/reports/FBgn0067319.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005455 l(1)v451 lethal (1) v451 http://flybase.net/reports/FBgn0005455.html gene l(1)451 16-Dec-15 2015_12 "male sterile,lethal,male,lethal - all die before end of larval stage,maternal effect,some die during larval stage" "egg chamber,germline clone,maternal effect" FBgn0261625 GLS Glutaminase http://flybase.net/reports/FBgn0261625.html FBgn0033765 protein_coding_gene 0004359=glutaminase activity "0006541=glutamine metabolic process, 0007476=imaginal disc-derived wing morphogenesis" 0005739=mitochondrion "Glutaminase, CG42708, CG8772, CG8872, GLS" "IPR012338=Beta-lactamase/transpeptidase-like, IPR015868=Glutaminase, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG42708 16-Dec-15 2015_12 viable FBgn0039411 dysf dysfusion http://flybase.net/reports/FBgn0039411.html "FBgn0039409, FBgn0039410, FBgn0039412" protein_coding_gene "0046982=protein heterodimerization activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007427=epithelial cell migration, open tracheal system, 0006355=regulation of transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035147=branch fusion, open tracheal system, 0007219=Notch signaling pathway, 0060571=morphogenesis of an epithelial fold, 0016348=imaginal disc-derived leg joint morphogenesis, 0007424=open tracheal system development, 0006357=regulation of transcription from RNA polymerase II promoter" "0043234=protein complex, 0005634=nucleus" "CG12561, NXF-like-factor, CG14552, Dys, CG32474, dys, Dysfusion, cranky, dNXFL, NXFL, CG14554, CG14553" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR001610=PAC motif, IPR000014=PAS domain" CG32474 16-Dec-15 2015_12 "ENSDARG00000055752(npas4),ENSDARG00000061920(LOC794051)" WBGene00000521(cky-1) ENSG00000174576(NPAS4) "lethal,recessive" "embryonic/larval ganglionic branch,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,ganglionic branch primordium | embryonic stage 16,lateral trunk primordium | embryonic stage 16,dorsal branch primordium | embryonic stage 16,dorsal trunk primordium | embryonic stage 16,visceral branch | embryonic stage 16" DRSC14895 E 0.235356986 -1.396830861 -0.305381765 -2.727490111 -0.17969087 -0.094437653 FBgn0052053 CG32053 http://flybase.net/reports/FBgn0052053.html FBgn0036067 protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CG6645 "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like" CG32053 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0259163 CG42268 http://flybase.net/reports/FBgn0259163.html "FBgn0052046, FBgn0036041, FBgn0052044, FBgn0036042" protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis "CG32046, CG6740, CG14170, CG32044" CG42268 16-Dec-15 2015_12 DRSC10171 IE 2.294236057 1.919991562 2.039172495 -1.637676671 0.864804219 1.482798318 FBgn0243514 eater eater http://flybase.net/reports/FBgn0243514.html "FBgn0082595, FBgn0039484" protein_coding_gene "0005044=scavenger receptor activity, 0042834=peptidoglycan binding" "0050766=positive regulation of phagocytosis, 0046331=lateral inhibition, 0042742=defense response to bacterium, 0006955=immune response, 0006910=phagocytosis, recognition, 0010811=positive regulation of cell-substrate adhesion, 0006909=phagocytosis, 0050830=defense response to Gram-positive bacterium" "0009986=cell surface, 0016021=integral component of membrane" "Dmel_CG6124, CT19227, C901-like, Eater, CG6124" "IPR003341=Cysteine rich repeat, tripleX, IPR000742=EGF-like domain" CG6124 16-Dec-15 2015_12 ENSDARG00000039652(LOC100004638) "WBGene00018026(F35A5.4),WBGene00004104(pqn-13),WBGene00008559(F07H5.8)" FBgn0011620 l(1)K49c28-A3 lethal (1) K49c28-A3 http://flybase.net/reports/FBgn0011620.html gene 16-Dec-15 2015_12 lethal FBgn0259409 EP-160 http://flybase.net/reports/FBgn0259409.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0262373 mir-9a mir-9a stem loop http://flybase.net/reports/FBgn0262373.html "FBgn0067680, FBgn0046813, FBgn0262184" miRNA_gene "0007476=imaginal disc-derived wing morphogenesis, 0035220=wing disc development, 0035195=gene silencing by miRNA, 0008052=sensory organ boundary specification" "miR-9a, dme-mir-9a, transfrag 22, dme-miR-9a, dme-miR-9a-5p, miR9a, mir-9, CR42891, miR-9, CR33063, mir-9a, mir-9A" CR42891 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0000218 brh brown head http://flybase.net/reports/FBgn0000218.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,denticle belt" FBgn0018737 Dns Dense http://flybase.net/reports/FBgn0018737.html gene 16-Dec-15 2015_12 "visible,dominant,viable" macrochaeta FBgn0031296 CG4415 http://flybase.net/reports/FBgn0031296.html protein_coding_gene 0051082=unfolded protein binding 0006605=protein targeting 0005854=nascent polypeptide-associated complex "IPR002715=Nascent polypeptide-associated complex NAC domain, IPR016641=Nascent polypeptide-associated complex subunit alpha" CG4415 16-Dec-15 2015_12 YHR193C(EGD2) "female fertile,viable" FBgn0040025 CG12577 http://flybase.net/reports/FBgn0040025.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031676 CG14040 http://flybase.net/reports/FBgn0031676.html protein_coding_gene "0005459=UDP-galactose transmembrane transporter activity, 0005351=sugar:proton symporter activity" 0008643=carbohydrate transport "0005797=Golgi medial cisterna, 0000139=Golgi membrane, 0016021=integral component of membrane" "IPR021189=UDP/CMP-sugar transporter, IPR007271=Nucleotide-sugar transporter" CG14040 16-Dec-15 2015_12 ENSDARG00000000001(slc35a5) ENSXETG00000002426(SLC35A5) ENSMUSG00000022664(Slc35a5) viable FBgn0264616 CR43956 http://flybase.net/reports/FBgn0264616.html non_protein_coding_gene CR43956 16-Dec-15 2015_12 FBgn0013395 anon-64Bc anon-64Bc http://flybase.net/reports/FBgn0013395.html gene 16-Dec-15 2015_12 FBgn0013520 l(1)rp3 lethal (1) rp3 http://flybase.net/reports/FBgn0013520.html gene 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0082340 HM56 HM56 http://flybase.net/reports/FBgn0082340.html gene 16-Dec-15 2015_12 FBgn0005374 x4 x4 http://flybase.net/reports/FBgn0005374.html gene 16-Dec-15 2015_12 FBgn0065923 l(2)SH0152 lethal (2) SH0152 http://flybase.net/reports/FBgn0065923.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027866 CG9776 http://flybase.net/reports/FBgn0027866.html FBan0009776 protein_coding_gene BcDNA:LD19168 CG9776 16-Dec-15 2015_12 ENSG00000171467(ZNF318) "viable,visible" trichogen cell FBgn0264712 CG1172 http://flybase.net/reports/FBgn0264712.html "FBgn0037321, FBgn0263450" protein_coding_gene "CR43473, CC1172" "IPR029071=Ubiquitin-related domain, IPR000626=Ubiquitin domain" CG1172 16-Dec-15 2015_12 "ENSDARG00000071200,ENSDARG00000069184(ubtd2),ENSDARG00000007382(ubtd1),ENSDARG00000043668" "ENSXETG00000014428(UBTD2),ENSXETG00000027099(BC074677.1)" "ENSMUSG00000044949(Ubtd2),ENSMUSG00000025171(Ubtd1)" "ENSG00000168246(UBTD2),ENSG00000165886(UBTD1)" FBgn0001724 l(1)ESHS45 lethal (1) ESHS45 http://flybase.net/reports/FBgn0001724.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000389 Cu-3 Curled 3 http://flybase.net/reports/FBgn0000389.html gene "Cur, Curl, Curl in chromosome 3" 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" wing FBgn0052066 CG32066 http://flybase.net/reports/FBgn0052066.html "FBgn0036092, FBgn0036095" protein_coding_gene 0098595=perivitelline space "CG6487, CG6491" IPR009828=Protein of unknown function DUF1394 CG32066 16-Dec-15 2015_12 "ENSDARG00000020929(fam49ba),ENSDARG00000045417(fam49bb),ENSDARG00000035907(fam49a),ENSDARG00000006672(znf395),ENSDARG00000068889" WBGene00019944(R07G3.8) "ENSXETG00000015482(fam49a),ENSXETG00000010951(fam49c),ENSXETG00000017755(FAM49B)" "ENSMUSG00000022378(Fam49b),ENSMUSG00000020589(Fam49a)" "ENSG00000153310(FAM49B),ENSG00000197872(FAM49A)" "viable,fertile" FBgn0062604 Mod(var)1429 Mod(var)1429 http://flybase.net/reports/FBgn0062604.html gene 0006342=chromatin silencing 1429 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0013529 l(2)23AB7 lethal (2) 23AB7 http://flybase.net/reports/FBgn0013529.html gene 16-Dec-15 2015_12 lethal FBgn0033943 CG12869 http://flybase.net/reports/FBgn0033943.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR002018=Carboxylesterase, type B" CG12869 16-Dec-15 2015_12 "viable,fertile" FBgn0266800 CR45262 http://flybase.net/reports/FBgn0266800.html non_protein_coding_gene CR45262 16-Dec-15 2015_12 FBgn0033340 CG13751 http://flybase.net/reports/FBgn0033340.html FBgn0047043 protein_coding_gene BcDNA:RH09719 CG13751 16-Dec-15 2015_12 viable FBgn0033149 CG11060 http://flybase.net/reports/FBgn0033149.html protein_coding_gene CG11060 16-Dec-15 2015_12 ENSMUSG00000039110(Mycbpap) viable FBgn0061071 l(3)S018310b lethal (3) S018310b http://flybase.net/reports/FBgn0061071.html gene 0183/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0001336 l(1)1Af lethal (1) 1Af http://flybase.net/reports/FBgn0001336.html gene 16-Dec-15 2015_12 lethal FBgn0019940 Rh6 Rhodopsin 6 http://flybase.net/reports/FBgn0019940.html protein_coding_gene 0008020=G-protein coupled photoreceptor activity "0043153=entrainment of circadian clock by photoperiod, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007601=visual perception, 0007186=G-protein coupled receptor signaling pathway, 0007602=phototransduction, 0007605=sensory perception of sound" "0016028=rhabdomere, 0016021=integral component of membrane" "Dm Rh6, CG5192, RH6, Rh, R8, rhodopsin 6, DMELRH6, rhodopsin, Rhodopsin6, Rhodopsin, rh6, rhodopsin-6, R8 rhodopsin" "IPR001735=Opsin RH1/RH2, IPR001760=Opsin, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR027430=Visual pigments (opsins) retinal binding site, IPR017452=GPCR, rhodopsin-like, 7TM" CG5192 16-Dec-15 2015_12 "ENSDARG00000007553(opn4l),ENSDARG00000053929(LOC566133),ENSDARG00000022098(opn4a),ENSDARG00000051908(si:dkeyp-100d11.3)" ENSXETG00000019216(OPN4) ENSMUSG00000021799(Opn4) ENSG00000122375(OPN4) adult stage " adult head

, photoreceptor cell R8 | subset

" "auditory perception defective,neurophysiology defective,viable" FBgn0053092 P5CDh2 delta-1-Pyrroline-5-carboxylate dehydrogenase 2 http://flybase.net/reports/FBgn0053092.html FBgn0038913 protein_coding_gene "0003842=1-pyrroline-5-carboxylate dehydrogenase activity, 0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" "0055114=oxidation-reduction process, 0006537=glutamate biosynthetic process, 0006562=proline catabolic process" 0005759=mitochondrial matrix "CG6670, DmP5CDh2, CG33092" "IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR015590=Aldehyde dehydrogenase domain, IPR016161=Aldehyde/histidinol dehydrogenase, IPR016163=Aldehyde dehydrogenase, C-terminal" CG33092 16-Dec-15 2015_12 YHR037W(PUT2) ENSXETG00000018531(ALDH4A1) FBgn0265630 sno strawberry notch http://flybase.net/reports/FBgn0265630.html "FBgn0001525, FBgn0003452, FBgn0265628, FBgn0005410" protein_coding_gene "0007219=Notch signaling pathway, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008587=imaginal disc-derived wing margin morphogenesis" 0005634=nucleus "CG44436, Strawberry Notch, CG1903, Sno, g-l, glossy-like, l(1)11Ea, Strawberry notch" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR026741=Protein strawberry notch, IPR026937=Strawberry notch, helicase C domain" CG44436 16-Dec-15 2015_12 ENSDARG00000003882(sbno2a) WBGene00003819 ENSXETG00000021579(SBNO2) ENSMUSG00000038095(Sbno1) ENSG00000139697(SBNO1) " larval stage , embryonic stage , adult stage && oogenesis stage , embryonic stage | stage 8 " " ventral thoracic disc | ubiquitous

, epidermis

, eye disc | ubiquitous

, embryonic central nervous system

, Malpighian tubule

, follicle cell

, dorsal mesothoracic disc | ubiquitous

, mesectoderm

, imaginal disc

" FBgn0084035 CG41475 http://flybase.net/reports/FBgn0084035.html "FBan0041475, FBgn0069940, FBgn0069941" protein_coding_gene "CG41104, CG41103" 16-Dec-15 2015_12 FBgn0266737 CR45210 http://flybase.net/reports/FBgn0266737.html non_protein_coding_gene CR45210 16-Dec-15 2015_12 FBgn0053116 CG33116 http://flybase.net/reports/FBgn0053116.html FBgn0032802 protein_coding_gene "0016780=phosphotransferase activity, for other substituted phosphate groups, 0008414=CDP-alcohol phosphotransferase activity" 0008654=phospholipid biosynthetic process 0016020=membrane "dCCS1, CG10355" "IPR014472=Choline/ethanolamine phosphotransferase, IPR000462=CDP-alcohol phosphatidyltransferase" CG33116 16-Dec-15 2015_12 ENSDARG00000060484(LOC557632) "YNL130C(CPT1),YHR123W(EPT1)" WBGene00018797(F54D7.2) ENSXETG00000003328(seli) ENSMUSG00000075703(Ept1) ENSG00000138018(EPT1) "viable,visible" "chaeta,supernumerary" FBgn0062620 Mod(var)1181 Mod(var)1181 http://flybase.net/reports/FBgn0062620.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1181 16-Dec-15 2015_12 "viable,reduced,suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0035227 Iml1 Increased minichromosome loss 1 http://flybase.net/reports/FBgn0035227.html protein_coding_gene 0005096=GTPase activator activity "1903432=regulation of TORC1 signaling, 0048142=germarium-derived cystoblast division" 0035859=Seh1-associated complex "CG12090, SEA1, iml1" IPR027244=Vacuolar membrane-associated protein Iml1 CG12090 16-Dec-15 2015_12 YJR138W(IML1) WBGene00011604(T08A11.1) ENSXETG00000004204(DEPDC5) ENSMUSG00000037426(Depdc5) ENSG00000100150(DEPDC5) "viable,fertile" FBgn0065535 l(2)SH1089 lethal (2) SH1089 http://flybase.net/reports/FBgn0065535.html gene l(2)SH2 1089 16-Dec-15 2015_12 "lethal,recessive" FBgn0045060 fs(1)137a female sterile (1) 137a http://flybase.net/reports/FBgn0045060.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "germarium,ovary" FBgn0020592 anon-57Ce anon-57Ce http://flybase.net/reports/FBgn0020592.html gene unnamed 16-Dec-15 2015_12 FBgn0001145 Gs2 Glutamine synthetase 2 http://flybase.net/reports/FBgn0001145.html protein_coding_gene 0004356=glutamate-ammonia ligase activity "0006542=glutamine biosynthetic process, 0007416=synapse assembly, 0045213=neurotransmitter receptor metabolic process, 0006538=glutamate catabolic process" 0005737=cytoplasm "Glutamate-ammonia ligase, Glutamine Synthetase 2, glutamine synthase 2, GS2, gs-c, gs2, glutamine synthetase 2, cytoplasmic glutamine synthetase, GsII, CG1743" "IPR008146=Glutamine synthetase, catalytic domain, IPR027302=Glutamine synthetase, N-terminal conserved site, IPR027303=Glutamine synthetase, glycine-rich site, IPR008147=Glutamine synthetase, beta-Grasp domain, IPR014746=Glutamine synthetase/guanido kinase, catalytic domain" CG1743 16-Dec-15 2015_12 "ENSDARG00000017339(glulb),ENSDARG00000069054(glula),ENSDARG00000013227(zgc:152741)" YPR035W(GLN1) WBGene00001604(gln-3) ENSXETG00000000380(Q6P348_XENTR) ENSMUSG00000026473(Glul) ENSG00000135821(GLUL) " adult stage , larval stage | first instar , larval stage | second instar " "neurophysiology defective,viable" FBgn0265297 pAbp http://flybase.net/reports/FBgn0265297.html "FBgn0261619, FBgn0003031, FBgn0021963, FBgn0027713, FBgn0027714, FBgn0063151, FBgn0065324, FBgn0025217, FBgn0040739" protein_coding_gene "0008143=poly(A) binding, 0005515=protein binding, 0000166=nucleotide binding, 0003729=mRNA binding, 0003730=mRNA 3'-UTR binding" "0007289=spermatid nucleus differentiation, 0007140=male meiosis, 0022008=neurogenesis, 0048599=oocyte development, 0045727=positive regulation of translation, 0007112=male meiosis cytokinesis, 0007268=synaptic transmission, 0045314=regulation of compound eye photoreceptor development, 0007283=spermatogenesis, 0000398=mRNA splicing, via spliceosome, 1901215=negative regulation of neuron death, 0009953=dorsal/ventral pattern formation, 0048477=oogenesis" "0005875=microtubule associated complex, 0071013=catalytic step 2 spliceosome, 0005811=lipid particle, 0030529=ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" "BcDNA:LD24412, anon-EST:Posey247, PABP55B, pABP, pAB, lethal (2) SH1908, Pabp, poly(A)-binding protein, anon-fast-evolving-2E5, unnamed, PABP, polyA-binding protein, l(2)k10109, poly-A binding protein, anon-EST:Posey249, Poly(A) Binding Protein, l(2)SH1908, PAbp, Poly(A)binding protein, PolyA-binding protein, anon-EST:fe2E5, poly (A)-binding protein, poly(A) binding protein, doppio fuso, pabp, dPABP, polyadenylate-binding protein, Poly(A)-binding protein, PABPC1, Poly(A) binding protein, l(2)SH2 1908, CG5119, duo, CG16803" "IPR002004=Polyadenylate-binding protein/Hyperplastic disc protein, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006515=Polyadenylate binding protein, human types 1, 2, 3, 4, IPR000504=RNA recognition motif domain" CG5119 16-Dec-15 2015_12 "ENSDARG00000059259(pabpc4),ENSDARG00000021140(pabpc1b),ENSDARG00000017219(pabpc1a),ENSDARG00000002597(pabpc1l)" YER165W(PAB1) "WBGene00003902(pab-1),WBGene00003903(pab-2)" "ENSXETG00000006635(PABPC1),ENSXETG00000010946(PABPC4),ENSXETG00000022831(BC076956.1)" "ENSMUSG00000011257(Pabpc4),ENSMUSG00000062093,ENSMUSG00000050667,ENSMUSG00000022283(Pabpc1),ENSMUSG00000051732(Pabpc2),ENSMUSG00000046173" "ENSG00000090621(PABPC4),ENSG00000070756(PABPC1),ENSG00000151846(PABPC3),ENSG00000101104(PABPC1L)" " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

DRSC07659 IEK 1.096973612 -6.200961709 -2.273655693 -3.389501586 3.14274607 2.47206588 FBgn0030841 CG8568 http://flybase.net/reports/FBgn0030841.html protein_coding_gene CG8568 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0265316 CR44289 http://flybase.net/reports/FBgn0265316.html non_protein_coding_gene lincRNA.872 CR44289 16-Dec-15 2015_12 FBgn0002174 l(2)tid lethal (2) tumorous imaginal discs http://flybase.net/reports/FBgn0002174.html FBgn0034896 protein_coding_gene "0005524=ATP binding, 0005113=patched binding, 0031072=heat shock protein binding, 0051082=unfolded protein binding" "0006457=protein folding, 0009408=response to heat, 0007224=smoothened signaling pathway" "0005739=mitochondrion, 0005829=cytosol" "cDNA 10D, l(2)tumorous disc, lethal (2) tumorous imaginal discs, tid, l(2)td, l(2)tud, l(2)tumorous imaginal discs, CG5504, TID56, DnaJ, l(2)701" "IPR018253=DnaJ domain, conserved site, IPR012724=Chaperone DnaJ, IPR001623=DnaJ domain, IPR008971=HSP40/DnaJ peptide-binding, IPR002939=Chaperone DnaJ, C-terminal, IPR001305=Heat shock protein DnaJ, cysteine-rich domain" CG5504 16-Dec-15 2015_12 "ENSDARG00000058494(dnaja3a),ENSDARG00000055606" YFL016C(MDJ1) WBGene00001028(dnj-10) ENSMUSG00000004069(Dnaja3) ENSG00000103423(DNAJA3) " larval stage , adult stage , embryonic stage -- adult stage " "wild-type,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,tumorigenic" "wing disc,imaginal disc" FBgn0058384 CG40384 http://flybase.net/reports/FBgn0058384.html FBan0040384 protein_coding_gene 16-Dec-15 2015_12 FBgn0264081 CG43750 http://flybase.net/reports/FBgn0264081.html protein_coding_gene CG43750 16-Dec-15 2015_12 FBgn0040547 CG14706 http://flybase.net/reports/FBgn0040547.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060966 l(3)S030901b lethal (3) S030901b http://flybase.net/reports/FBgn0060966.html gene 0309/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0030913 CG6123 http://flybase.net/reports/FBgn0030913.html protein_coding_gene CG6123 16-Dec-15 2015_12 viable DRSC30011 K 0.444283181 0.274089522 -0.061174379 0.575082419 1.316855014 1.906566258 FBgn0267015 CR45459 http://flybase.net/reports/FBgn0267015.html non_protein_coding_gene CR45459 16-Dec-15 2015_12 FBgn0000318 cl clot http://flybase.net/reports/FBgn0000318.html "FBgn0031709, FBgn0063070" protein_coding_gene 0015036=disulfide oxidoreductase activity 0006726=eye pigment biosynthetic process "CG11024, BcDNA:RE06767" "IPR010357=Protein of unknown function DUF953, thioredoxin-like, IPR012336=Thioredoxin-like fold" CG11024 16-Dec-15 2015_12 ENSDARG00000058079(txndc17) WBGene00022188(Y71H2AR.1) ENSMUSG00000020803(Txndc17) ENSG00000129235(TXNDC17) "viable,fertile,eye color defective" "Malpighian tubule,pigment cell" FBgn0267920 CR46201 http://flybase.net/reports/FBgn0267920.html non_protein_coding_gene lincRNA.919 CR46201 16-Dec-15 2015_12 FBgn0262118 l(2)NC173 http://flybase.net/reports/FBgn0262118.html gene 16-Dec-15 2015_12 FBgn0031281 Saf6 SAGA factor-like TAF6 http://flybase.net/reports/FBgn0031281.html protein_coding_gene 0046982=protein heterodimerization activity 0045944=positive regulation of transcription from RNA polymerase II promoter "0000124=SAGA complex, 0005634=nucleus, 0070461=SAGA-type complex" "saf6, CG3883, SAF6" CG3883 16-Dec-15 2015_12 "viable,fertile" DRSC00633 E -0.149480242 0.362396254 -0.241661292 1.692060646 -0.448121921 0.217145176 FBgn0023433 l(2)4-3A lethal (2) 4-3A http://flybase.net/reports/FBgn0023433.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0019845 anon-XXIII anon-XXIII http://flybase.net/reports/FBgn0019845.html gene XXIII 16-Dec-15 2015_12 FBgn0005284 M(3)S36 Minute (3) 36 http://flybase.net/reports/FBgn0005284.html gene M(3)s36 16-Dec-15 2015_12 "Minute,dominant,visible" macrochaeta FBgn0069447 E(br)333 E(br)333 http://flybase.net/reports/FBgn0069447.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,semidominant" leg FBgn0044411 Scim16 Sensitized chromosome inheritance modifier 16 http://flybase.net/reports/FBgn0044411.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0011195 l(1)302-9 lethal (1) 302-9 http://flybase.net/reports/FBgn0011195.html FBgn0010202 gene 302-9 16-Dec-15 2015_12 "lethal,recessive" FBgn0053964 CG33964 http://flybase.net/reports/FBgn0053964.html "FBgn0033694, FBgn0033695, FBgn0053154, FBtr0087990, FBpp0087098, FBtr0087991, FBpp0087099" protein_coding_gene "CG13174, CT32415, CG8447, CG33154" "IPR025714=Methyltransferase domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG33964 16-Dec-15 2015_12 ENSDARG00000045754(zgc:136889) ENSXETG00000014540(C12orf26) FBgn0046123 E(To)12 E(To)12 http://flybase.net/reports/FBgn0046123.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037638 CG8379 http://flybase.net/reports/FBgn0037638.html FBgn0062144 protein_coding_gene anon-WO0118547.250 IPR013636=Domain of unknown function DUF1741 CG8379 16-Dec-15 2015_12 ENSDARG00000030790(zgc:63733) ENSXETG00000006269(C10orf76) ENSMUSG00000039901(9130011E15Rik) ENSG00000120029(C10orf76) "viable,fertile" FBgn0267432 kl-3 male fertility factor kl3 http://flybase.net/reports/FBgn0267432.html "FBgn0085550, FBan0040992, FBgn0085539, FBan0040936, FBgn0016045, FBgn0040039, FBgn0058443, FBan0017629, FBgn0001314" protein_coding_gene "0042623=ATPase activity, coupled, 0003777=microtubule motor activity, 0003774=motor activity, 0008017=microtubule binding, 0005524=ATP binding" 0007018=microtubule-based movement "0005858=axonemal dynein complex, 0005875=microtubule associated complex" "CG40992, Lms3, CG40936, male fertility factor kl-3, Y104b, gamma-dynein heavy chain, CG45785, kl-4, kl3, CG17629, ms(Y)104b, CG40443" "IPR024743=Dynein heavy chain, coiled coil stalk, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR011704=ATPase, dynein-related, AAA domain, IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR013594=Dynein heavy chain, domain-1, IPR004273=Dynein heavy chain domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG45785 16-Dec-15 2015_12 FBgn0264277 Su(Mir)3 http://flybase.net/reports/FBgn0264277.html gene 16-Dec-15 2015_12 lethal FBgn0062572 Mod(var)E1350 Mod(var)E1350 http://flybase.net/reports/FBgn0062572.html gene 0006342=chromatin silencing E1350 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0041827 ISO-Q ISO-Q http://flybase.net/reports/FBgn0041827.html gene 16-Dec-15 2015_12 "flightless,recessive" FBgn0028146 l(3)S045507b lethal (3) S045507b http://flybase.net/reports/FBgn0028146.html gene "l(3)S045507, 0455/07" 16-Dec-15 2015_12 "lethal,recessive" FBgn0053404 5SrRNA:CR33404 5SrRNA:CR33404 http://flybase.net/reports/FBgn0053404.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33404 CR33404 16-Dec-15 2015_12 FBgn0083278 E(smoDN)2515 Enhancer of smoDN 2515 http://flybase.net/reports/FBgn0083278.html gene 16-Dec-15 2015_12 FBgn0267005 CR45449 http://flybase.net/reports/FBgn0267005.html non_protein_coding_gene CR45449 16-Dec-15 2015_12 FBgn0065750 l(2)SH0498 lethal (2) SH0498 http://flybase.net/reports/FBgn0065750.html gene l(2)SH2 0498 16-Dec-15 2015_12 "lethal,recessive" FBgn0027142 l(3)71EFa lethal (3) 71EFa http://flybase.net/reports/FBgn0027142.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0031896 CG4502 http://flybase.net/reports/FBgn0031896.html FBgn0062037 protein_coding_gene anon-WO0118547.403 "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG4502 16-Dec-15 2015_12 ENSMUSG00000052981 "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267956 CR46236 http://flybase.net/reports/FBgn0267956.html non_protein_coding_gene lincRNA.901 CR46236 16-Dec-15 2015_12 FBgn0262395 mir-12 mir-12 stem loop http://flybase.net/reports/FBgn0262395.html "FBgn0046831, FBgn0262225" miRNA_gene "0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0045880=positive regulation of smoothened signaling pathway, 0035195=gene silencing by miRNA" "dme-miR-12, dme-mir-12, CR33076, mir-12, Mir-12, pri-miR-12, dme-miR-12-3p, miR-12, MiR-12, CR42932, miR12" CR42932 16-Dec-15 2015_12 embryonic stage -- adult stage "visible,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein,wing margin" FBgn0069233 gl(2L)179-26 gl(2L)179-26 http://flybase.net/reports/FBgn0069233.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "egg,germline clone,maternal effect,dorsal appendage,cephalopharyngeal skeleton" FBgn0040824 CG14169 http://flybase.net/reports/FBgn0040824.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033566 CG18004 http://flybase.net/reports/FBgn0033566.html protein_coding_gene "0006260=DNA replication, 0006281=DNA repair" 0031011=Ino80 complex IPR026678=INO80 complex subunit E CG18004 16-Dec-15 2015_12 ENSMUSG00000030689(Ino80e) ENSG00000169592(INO80E) FBgn0037655 CG11984 http://flybase.net/reports/FBgn0037655.html protein_coding_gene "0008270=zinc ion binding, 0015459=potassium channel regulator activity" "IPR008598=Drought induced 19 protein type, zinc-binding domain, IPR015880=Zinc finger, C2H2-like, IPR000433=Zinc finger, ZZ-type" CG11984 16-Dec-15 2015_12 ENSDARG00000067656(kcmf1) ENSG00000176407(KCMF1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017461 TfIIIB Transcription factor IIIB http://flybase.net/reports/FBgn0017461.html gene 0006383=transcription from RNA polymerase III promoter "TFIIIB, IIIB" 16-Dec-15 2015_12 FBgn0001642 l(1)dn22 lethal (1) discs normal 22 http://flybase.net/reports/FBgn0001642.html gene l(1)d.norm.-22 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085287 CG34258 http://flybase.net/reports/FBgn0085287.html protein_coding_gene CG34258 16-Dec-15 2015_12 FBgn0015337 anon-23EFa anon-23EFa http://flybase.net/reports/FBgn0015337.html gene 16-Dec-15 2015_12 FBgn0004578 l(3)hem lethal (3) hematopoiesis missing http://flybase.net/reports/FBgn0004578.html gene l-(3)hem 16-Dec-15 2015_12 "cytokinesis defective,recessive,lethal - all die before end of larval stage,some die during larval stage" "prohemocyte,plasmatocyte,crystal cell,embryonic/larval lymph gland,embryonic/larval optic lobe,neuroblast" FBgn0028093 l(3)S078514 lethal (3) S078514 http://flybase.net/reports/FBgn0028093.html gene 0785/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0084050 CR41470 http://flybase.net/reports/FBgn0084050.html FBan0041470 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0017436 anon-28Cc anon-28Cc http://flybase.net/reports/FBgn0017436.html gene unnamed 16-Dec-15 2015_12 FBgn0035550 CG11349 http://flybase.net/reports/FBgn0035550.html protein_coding_gene CG11349 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0004081 XDm XDm element http://flybase.net/reports/FBgn0004081.html repeat_region unnamed 16-Dec-15 2015_12 FBgn0024720 Su(var)99C99E Su(var)99C99E http://flybase.net/reports/FBgn0024720.html gene unnamed 16-Dec-15 2015_12 FBgn0003583 Su(stn) Suppressor of stoned http://flybase.net/reports/FBgn0003583.html gene 16-Dec-15 2015_12 FBgn0020616 SA Stromalin http://flybase.net/reports/FBgn0020616.html FBgn0020933 protein_coding_gene 0003682=chromatin binding "0007064=mitotic sister chromatid cohesion, 0016322=neuron remodeling" "0034990=nuclear mitotic cohesin complex, 0005721=pericentric heterochromatin, 0000922=spindle pole, 0000780=condensed nuclear chromosome, centromeric region, 0035327=transcriptionally active chromatin, 0008278=cohesin complex, 0005634=nucleus" "SCC3, CG3423, DSA1, DSA, cohesin, ESTS:92H2T, stromalin, Scc3, DmSA" "IPR013721=STAG, IPR016024=Armadillo-type fold, IPR020839=Stromalin conservative domain" CG3423 16-Dec-15 2015_12 "ENSDARG00000062137(LOC563669),ENSDARG00000061205(LOC564533),ENSDARG00000011783(si:dkeyp-20g2.6)" YIL026C(IRR1) WBGene00004738(scc-3) ENSXETG00000014393(STAG1) "ENSMUSG00000037286(Stag1),ENSMUSG00000025862(Stag2),ENSMUSG00000036928(Stag3)" "ENSG00000118007(STAG1),ENSG00000101972(STAG2),ENSG00000066923(STAG3)" "lethal - all die before end of pupal stage,partially,some die during pupal stage,planar polarity defective" DRSC03424 K -0.223030754 0.870827593 0.051109107 1.44912264 1.790112427 2.615684226 FBgn0029672 CG2875 http://flybase.net/reports/FBgn0029672.html protein_coding_gene "0042254=ribosome biogenesis, 0022008=neurogenesis" "IPR005612=CCAAT-binding factor, IPR027193=Nucleolar complex protein 4" CG2875 16-Dec-15 2015_12 ENSDARG00000045565(noc4l) YPR144C(NOC4) ENSXETG00000002043(Q68EN9_XENTR) ENSMUSG00000033294(Noc4l) ENSG00000184967(NOC4L) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0053170 CG33170 http://flybase.net/reports/FBgn0053170.html "FBgn0037198, FBgn0064990" protein_coding_gene "CG8244, BcDNA:AT30788" IPR027854=Protein of unknown function DUF4535 CG33170 16-Dec-15 2015_12 viable FBgn0027998 l(3)S122404 lethal (3) S122404 http://flybase.net/reports/FBgn0027998.html gene 1224/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0083990 sphinx sphinx http://flybase.net/reports/FBgn0083990.html FBgn0039931 non_protein_coding_gene 0008049=male courtship behavior "spx, CR34154, Sphinx" CR34154 16-Dec-15 2015_12 "courtship behavior defective,male limited" FBgn0001347 l(1)1Eb lethal (1) 1Eb http://flybase.net/reports/FBgn0001347.html gene HM-14 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,recessive,lethal" FBgn0266156 CR44862 http://flybase.net/reports/FBgn0266156.html non_protein_coding_gene CR44862 16-Dec-15 2015_12 FBgn0034168 CG15614 http://flybase.net/reports/FBgn0034168.html protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG15614 16-Dec-15 2015_12 viable FBgn0032865 CG15477 http://flybase.net/reports/FBgn0032865.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0058271 CG40271 http://flybase.net/reports/FBgn0058271.html FBan0040271 protein_coding_gene 16-Dec-15 2015_12 FBgn0044338 297\gag gag http://flybase.net/reports/FBgn0044338.html transposable_element_gene gag 16-Dec-15 2015_12 FBgn0029697 CG15570 http://flybase.net/reports/FBgn0029697.html protein_coding_gene 0042600=chorion CG15570 16-Dec-15 2015_12 viable FBgn0039999 CG17787 http://flybase.net/reports/FBgn0039999.html FBgn0058398 protein_coding_gene CG40398 16-Dec-15 2015_12 FBgn0050391 CG30391 http://flybase.net/reports/FBgn0050391.html FBgn0034607 protein_coding_gene CG15662 CG30391 16-Dec-15 2015_12 viable FBgn0015434 l(1)4Da lethal (1) 4Da http://flybase.net/reports/FBgn0015434.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0066130 E(sda)C E(sda)C http://flybase.net/reports/FBgn0066130.html gene Line C 16-Dec-15 2015_12 FBgn0039969 Fis1 http://flybase.net/reports/FBgn0039969.html "FBgn0046054, FBgn0047128" protein_coding_gene "0090141=positive regulation of mitochondrial fission, 0007005=mitochondrion organization" 0005778=peroxisomal membrane "dFis1, CG17510, BcDNA:RE29957, NEST:bs15a08, bs15a08.y1" "IPR028058=Fis1, N-terminal tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR016543=Mitochondria fission 1 protein, IPR028061=Fis1, C-terminal tetratricopeptide repeat" CG17510 16-Dec-15 2015_12 YIL065C(FIS1) WBGene00001425(fis-2) ENSMUSG00000019054(Fis1) ENSG00000214253(FIS1) FBgn0010883 l(3)06240 lethal (3) 06240 http://flybase.net/reports/FBgn0010883.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039034 Or94b Odorant receptor 94b http://flybase.net/reports/FBgn0039034.html "FBgn0067028, FBgn0067029" protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "anon-JP2002534971-A.31, CG6679, anon-JP2002534971-A.32, 94b, DOR109, 94D.2" "IPR004117=Olfactory receptor, Drosophila" CG6679 16-Dec-15 2015_12 smell perception defective FBgn0022160 Gpo-1 Glycerophosphate oxidase-1 http://flybase.net/reports/FBgn0022160.html "FBgn0001129, FBgn0034048, FBgn0042124, FBgn0062235" protein_coding_gene "0004368=glycerol-3-phosphate dehydrogenase activity, 0005509=calcium ion binding" "0006071=glycerol metabolic process, 0006072=glycerol-3-phosphate metabolic process, 0007629=flight behavior, 0006127=glycerophosphate shuttle, 0022008=neurogenesis" "0005743=mitochondrial inner membrane, 0005811=lipid particle, 0005739=mitochondrion, 0009331=glycerol-3-phosphate dehydrogenase complex" "anon-WO0118547.114, alpha glycerophosphate oxidase, CG 8256, glycerophosphate oxidase, alpha-GPO, GPO-1, Mitochondrial glycerol-3-phosphate dehydrogenase, CG8256, Gpo, l(2)k05713, lethal (2) k05713, mitochondrial GPD, alpha-glycerophosphate oxidase, Gpo-1, 1(2) K05713, alpha-Glycerophosphate oxidase, GPO, alphaGPO, CG18786" "IPR002048=EF-hand domain, IPR006076=FAD dependent oxidoreductase, IPR000447=FAD-dependent glycerol-3-phosphate dehydrogenase, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG8256 16-Dec-15 2015_12 ENSDARG00000062430(gpd2) YIL155C(GUT2) WBGene00012031(T25G3.4) ENSXETG00000024015(GPD2) ENSMUSG00000026827(Gpd2) ENSG00000115159(GPD2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,recessive,viable,flightless" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0250910 Octë_3R Octopamine ë_3 receptor http://flybase.net/reports/FBgn0250910.html "FBpp0082144, FBtr0082675, FBpp0082143, FBtr0082674, FBtr0082677, FBpp0082146, FBgn0053959, FBgn0038061, FBgn0046559, FBgn0046560, FBgn0051348, FBgn0051350, FBgn0051351, FBgn0038060, FBan0031348, FBan0031351, FBan0031350, FBgn0054055" protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0004989=octopamine receptor activity" "0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "OctBeta3, Octbeta3R, octopamine receptor beta3, CG34055, DmCG7078, CG33959, anon-WO0170980.187, anon-WO0170980.188, Octb3R, CG31348, CG18554, CG7078, CG31350, DmOctbeta3R, octbeta3R, octRbeta3, CG42244, CG31351" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG42244 16-Dec-15 2015_12 """DRSC15351, DRSC24019"" " IEK FBgn0066126 E(sda)H E(sda)H http://flybase.net/reports/FBgn0066126.html gene Line H 16-Dec-15 2015_12 "lethal,recessive" FBgn0036560 CG5895 http://flybase.net/reports/FBgn0036560.html protein_coding_gene 0008081=phosphoric diester hydrolase activity 0006629=lipid metabolic process "IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG5895 16-Dec-15 2015_12 "viable,fertile" FBgn0084022 CG41461 http://flybase.net/reports/FBgn0084022.html FBan0041461 protein_coding_gene 16-Dec-15 2015_12 FBgn0052104 CG32104 http://flybase.net/reports/FBgn0052104.html "FBgn0036280, FBgn0036281, FBgn0040243" protein_coding_gene "CG14124, anon-69Ag, CG14123" "IPR013929=RNA polymerase II-associated protein 1, C-terminal, IPR013930=RNA polymerase II-associated protein 1, N-terminal, IPR016024=Armadillo-type fold" CG32104 16-Dec-15 2015_12 ENSXETG00000000054(RPAP1) ENSMUSG00000034032(Rpap1) ENSG00000103932(RPAP1) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0065963 l(2)SH0026 lethal (2) SH0026 http://flybase.net/reports/FBgn0065963.html gene l(2)SH2 0026 16-Dec-15 2015_12 "lethal,recessive" FBgn0032065 CG12438 http://flybase.net/reports/FBgn0032065.html protein_coding_gene CG12438 16-Dec-15 2015_12 viable FBgn0025115 Acyp Acylphosphatase http://flybase.net/reports/FBgn0025115.html protein_coding_gene 0003998=acylphosphatase activity "CG16870, AcPDro, ACPDro, acylphosphatase, BG:DS00180.1" "IPR001792=Acylphosphatase-like domain, IPR017968=Acylphosphatase, conserved site, IPR020456=Acylphosphatase" CG16870 16-Dec-15 2015_12 FBgn0265397 EP2124 http://flybase.net/reports/FBgn0265397.html gene 16-Dec-15 2015_12 FBgn0005702 l(1)TK105 lethal (1) TK105 http://flybase.net/reports/FBgn0005702.html gene l105 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina,optic lobe" FBgn0065165 l(3)SH034 lethal (3) SH034 http://flybase.net/reports/FBgn0065165.html gene l(2)SH3 034 16-Dec-15 2015_12 "lethal,recessive" FBgn0263517 mir-4976 mir-4976 stem loop http://flybase.net/reports/FBgn0263517.html miRNA_gene "CR43502, dme-mir-4976" CR43502 16-Dec-15 2015_12 viable FBgn0042681 Rt1b\RTase RTase http://flybase.net/reports/FBgn0042681.html transposable_element_gene "Waldo-A\RTase, ORF2" 16-Dec-15 2015_12 FBgn0002175 l(3)5G83 lethal (3) 5G83 http://flybase.net/reports/FBgn0002175.html gene 16-Dec-15 2015_12 lethal dorsal closure embryo FBgn0267003 CR45447 http://flybase.net/reports/FBgn0267003.html non_protein_coding_gene CR45447 16-Dec-15 2015_12 FBgn0000200 bly bellyache http://flybase.net/reports/FBgn0000200.html gene 0007443=Malpighian tubule morphogenesis 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic Malpighian tubule,embryonic/larval midgut" FBgn0262815 CR43186 http://flybase.net/reports/FBgn0262815.html pseudogene_attribute "DMG6-MB6.chr2R.20.008, CG43186" CR43186 16-Dec-15 2015_12 FBgn0005117 l(1)FMa lethal (1) FMa http://flybase.net/reports/FBgn0005117.html gene l(1)69a 16-Dec-15 2015_12 "lethal,recessive" FBgn0086373 EP3916 http://flybase.net/reports/FBgn0086373.html gene 16-Dec-15 2015_12 FBgn0028841 jhamt juvenile hormone acid methyltransferase http://flybase.net/reports/FBgn0028841.html protein_coding_gene "0035049=juvenile hormone acid methyltransferase activity, 0019010=farnesoic acid O-methyltransferase activity" 0006718=juvenile hormone biosynthetic process "DmJHAMT, Juvenile hormone acid O-methyltransferase, Juvenile hormone acid methyl transferase, BG:DS09218.5, Jhamt, CG17330, JHAMT, JAHMT, JHamt" "IPR013217=Methyltransferase type 12, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG17330 16-Dec-15 2015_12 "developmental rate defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,viable" male genitalia FBgn0004209 l(3)84Eg lethal (3) 84Eg http://flybase.net/reports/FBgn0004209.html gene 16-Dec-15 2015_12 lethal FBgn0002801 ms(1)19E male sterile (1) 19E http://flybase.net/reports/FBgn0002801.html gene ms(1)E 16-Dec-15 2015_12 male sterile FBgn0260611 2L1794 http://flybase.net/reports/FBgn0260611.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0041594 l(3)10 lethal (3) 10 http://flybase.net/reports/FBgn0041594.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0062681 EP1595 EP1595 http://flybase.net/reports/FBgn0062681.html gene EP(X)1595 16-Dec-15 2015_12 "visible,lethal" eye FBgn0021846 l(2)k14805 lethal (2) k14805 http://flybase.net/reports/FBgn0021846.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038439 Cad89D Cadherin 89D http://flybase.net/reports/FBgn0038439.html protein_coding_gene 0005509=calcium ion binding "0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0044331=cell-cell adhesion mediated by cadherin, 0007155=cell adhesion, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "DCad89D, CT34724, CG14900, Cad89D" "IPR020894=Cadherin conserved site, IPR002126=Cadherin, IPR015919=Cadherin-like" CG14900 16-Dec-15 2015_12 "viable,fertile,body color defective" mesothoracic tergum FBgn0040036 CG12550 http://flybase.net/reports/FBgn0040036.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014141 cher cheerio http://flybase.net/reports/FBgn0014141.html "FBgn0016063, FBgn0023208" protein_coding_gene "0003779=actin binding, 0051015=actin filament binding" "0008355=olfactory learning, 0030708=germarium-derived female germ-line cyst encapsulation, 0007067=mitotic nuclear division, 0008302=female germline ring canal formation, actin assembly, 0035204=negative regulation of lamellocyte differentiation, 0007301=female germline ring canal formation, 0007611=learning or memory, 0030725=germline ring canal formation, 0008045=motor neuron axon guidance, 0008104=protein localization, 0048149=behavioral response to ethanol, 0008340=determination of adult lifespan" "0048471=perinuclear region of cytoplasm, 0070938=contractile ring, 0005634=nucleus, 0005829=cytosol, 0045179=apical cortex, 0005884=actin filament, 0035182=female germline ring canal outer rim, 0035183=female germline ring canal inner rim" "FLN, filamin, Filamin isoform B, filamin-240, filamin B, CG3937, shi kong, joy, sko, Fil, Filamin-1, Cheerio, Cher, Filamin, Filamin-A" "IPR013783=Immunoglobulin-like fold, IPR001715=Calponin homology domain, IPR017868=Filamin/ABP280 repeat-like, IPR028559=Filamin A/C, IPR014756=Immunoglobulin E-set, IPR001298=Filamin/ABP280 repeat, IPR001589=Actinin-type actin-binding domain, conserved site" CG3937 16-Dec-15 2015_12 "ENSDARG00000018566(flnca),ENSDARG00000060814(flnbl),ENSDARG00000018820(flncb)" "ENSXETG00000008663(FLNB),ENSXETG00000014956(FLNC),ENSXETG00000014268(FLNA)" "ENSMUSG00000031328(Flna),ENSMUSG00000025278(Flnb),ENSMUSG00000068699(Flnc)" "ENSG00000196924(FLNA),ENSG00000136068(FLNB),ENSG00000128591(FLNC)" " adult stage , adult stage && oogenesis stage " " follicle cell

, inner nurse cell ring canal rim

, ring canal

, fusome

, outer nurse cell ring canal rim

, ovariole | surrounding

, ovariole

, nurse cell

, interfollicle cell

" "female sterile,recessive,learning defective,memory defective,neuroanatomy defective,viable,fertile,chemical sensitive,visible,short lived,locomotor behavior defective,uncoordinated,heat sensitive,male fertile,long lived" "nurse cell ring canal,egg chamber,border follicle cell,interfollicle cell,germarium region 2b & interfollicle cell,follicle cell,intersegmental nerve,ommatidium,ovary,ovariole,germarium,nurse cell,plasma membrane & nurse cell,plasma membrane & oocyte,nurse cell & nucleus,centripetally migrating follicle cell,nurse cell & plasma membrane,oocyte,inner nurse cell ring canal rim,lamellocyte,ectopic" FBgn0266109 mei-114 meiotic 114 http://flybase.net/reports/FBgn0266109.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female" FBgn0014353 ms(3)ry5 ms(3)ry5 http://flybase.net/reports/FBgn0014353.html FBgn0013666 gene ms(3)5 16-Dec-15 2015_12 male sterile FBgn0027248 l(1)G0260 lethal (1) G0260 http://flybase.net/reports/FBgn0027248.html gene 16-Dec-15 2015_12 "female sterile,lethal,partially lethal - majority die,recessive" FBgn0013732 sced scrambled http://flybase.net/reports/FBgn0013732.html FBgn0033082 protein_coding_gene "0030037=actin filament reorganization involved in cell cycle, 0030589=pseudocleavage involved in syncytial blastoderm formation" 0005813=centrosome "CT9143, Sced, CG3273" CG3273 16-Dec-15 2015_12 "lethal,maternal effect,recessive,fertile,female sterile,viable" "embryonic/larval hemocyte | third instar larval stage,cycle 9 embryo,maternal effect,cycle 10 embryo,cycle 11 embryo,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo" FBgn0041177 Ubx::Akap\Ubx Ubx http://flybase.net/reports/FBgn0041177.html engineered_fusion_gene 16-Dec-15 2015_12 "embryonic metathoracic segment,embryonic abdominal segment 1,ectopic,leg,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0034194 CG15611 http://flybase.net/reports/FBgn0034194.html protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0035025=positive regulation of Rho protein signal transduction, 0034976=response to endoplasmic reticulum stress" "IPR000219=Dbl homology (DH) domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG15611 16-Dec-15 2015_12 "ENSDARG00000004780,ENSDARG00000063538(zgc:136817),ENSDARG00000030766,ENSDARG00000014465(im:7156160)" "ENSXETG00000013866(),ENSXETG00000009707(SPATA13)" ENSMUSG00000019467(D10Ertd610e) ENSG00000135502(SLC26A10) viable FBgn0267081 CR45525 http://flybase.net/reports/FBgn0267081.html non_protein_coding_gene CR45525 16-Dec-15 2015_12 FBgn0065299 l(2)SH1992 lethal (2) SH1992 http://flybase.net/reports/FBgn0065299.html gene l(2)SH2 1992 16-Dec-15 2015_12 "lethal,recessive" FBgn0265706 CR44513 http://flybase.net/reports/FBgn0265706.html non_protein_coding_gene lincRNA.399 CR44513 16-Dec-15 2015_12 FBgn0069915 CG41138 http://flybase.net/reports/FBgn0069915.html FBan0041138 protein_coding_gene 16-Dec-15 2015_12 FBgn0005572 l(3)85Eh lethal (3) 85Eh http://flybase.net/reports/FBgn0005572.html gene 16-Dec-15 2015_12 lethal FBgn0033924 CG8613 http://flybase.net/reports/FBgn0033924.html protein_coding_gene 0003824=catalytic activity "IPR024705=Spermatogenesis-associated protein 20, IPR012336=Thioredoxin-like fold, IPR004879=Domain of unknown function DUF255, IPR012341=Six-hairpin glycosidase, IPR008928=Six-hairpin glycosidase-like" CG8613 16-Dec-15 2015_12 ENSDARG00000013880(wu:fj02d07) WBGene00015204(B0495.5) ENSXETG00000009999(SPATA20) ENSMUSG00000020867(Spata20) ENSG00000006282(SPATA20) FBgn0000154 B Bar http://flybase.net/reports/FBgn0000154.html gene 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity "0036011=imaginal disc-derived leg segmentation, 0008407=chaeta morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035218=leg disc development" 0005634=nucleus "Ultrabar, Bar, bar, BB, Bar eye, BarH1, InfraBar" 16-Dec-15 2015_12 "wild-type,visible,dominant,recessive,cold sensitive,viable,female fertile,lethal,male fertile,poor,neuroanatomy defective,fertile,male" "eye,wing,cold sensitive,macrochaeta,tarsal segment 4,anterior,tarsal segment 3,pretarsus,ommatidium,morphogenetic furrow,optic lobe,medial ocellus,unguis,femur,tibia,metatarsus" FBgn0024849 nkg nanking http://flybase.net/reports/FBgn0024849.html gene "0007287=Nebenkern assembly, 0007291=sperm individualization" ms(3)3915 16-Dec-15 2015_12 "male sterile,recessive,viable" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus,Nebenkern" FBgn0065764 l(2)SH0475 lethal (2) SH0475 http://flybase.net/reports/FBgn0065764.html gene l(2)SH2 0475 16-Dec-15 2015_12 "lethal,recessive" FBgn0033048 CG7881 http://flybase.net/reports/FBgn0033048.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG7881 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0051171 CG31171 http://flybase.net/reports/FBgn0051171.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033931 Obp50e Odorant-binding protein 50e http://flybase.net/reports/FBgn0033931.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG13939, DmelObp50e" IPR006170=Pheromone/general odorant binding protein CG13939 16-Dec-15 2015_12 DRSC06434 E 0.012252043 0.51141493 0.09562802 1.659874165 -0.917623538 0.457580055 FBgn0267164 CR45604 http://flybase.net/reports/FBgn0267164.html non_protein_coding_gene CR45604 16-Dec-15 2015_12 FBgn0265263 CG42688 http://flybase.net/reports/FBgn0265263.html "FBgn0261578, FBgn0066992" protein_coding_gene "anon-SAGE:Wang-006, DMG8-chr2L.34.001" CG42688 16-Dec-15 2015_12 FBgn0013651 ms(2)ry7 ms(2)ry7 http://flybase.net/reports/FBgn0013651.html gene "unnamed, ms(2)7" 16-Dec-15 2015_12 male sterile FBgn0085346 CG34317 http://flybase.net/reports/FBgn0085346.html "FBan0007950, FBgn0039745" protein_coding_gene 0004540=ribonuclease activity 0008033=tRNA processing Dromel_CG7950_FBtr0085563_CHCHD4inmorf_uORF IPR002759=Ribonuclease P/MRP protein subunit CG34317 16-Dec-15 2015_12 "ENSDARG00000011152(rpp14),ENSDARG00000071574" ENSMUSG00000023156(Rpp14) ENSG00000163684(RPP14) FBgn0035989 CG3967 http://flybase.net/reports/FBgn0035989.html protein_coding_gene 0019799=tubulin N-acetyltransferase activity "0071929=alpha-tubulin acetylation, 0048149=behavioral response to ethanol" 0005874=microtubule IPR007965=Alpha-tubulin N-acetyltransferase CG3967 16-Dec-15 2015_12 ENSDARG00000004472(zgc:65893) WBGene00021059(W06B11.1) ENSMUSG00000024426(2610110G12Rik) "ENSG00000206405,ENSG00000206488,ENSG00000137343(ATAT1)" "learning defective,hyperactive,conditional,chemical resistant,viable" FBgn0082630 S(CycEJP)2.8 S(CycEJP)2.8 http://flybase.net/reports/FBgn0082630.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033680 CG13186 http://flybase.net/reports/FBgn0033680.html FBgn0063341 protein_coding_gene "BcDNA:AT11581, AAF58585" CG13186 16-Dec-15 2015_12 ENSMUSG00000076437(2700094K13Rik) FBgn0011295 CG11297 http://flybase.net/reports/FBgn0011295.html protein_coding_gene "anon2L, anon-21DEa, unnamed, anon-2L, P28" 16-Dec-15 2015_12 FBgn0003869 tta tetanic http://flybase.net/reports/FBgn0003869.html gene 16-Dec-15 2015_12 "visible,heat sensitive,female sterile,behavior defective" "wing,neck,abdomen,proboscis" FBgn0034737 CG11362 http://flybase.net/reports/FBgn0034737.html protein_coding_gene CG11362 16-Dec-15 2015_12 viable FBgn0262822 CR43193 http://flybase.net/reports/FBgn0262822.html non_protein_coding_gene "mdcds_58258, CG43193" CR43193 16-Dec-15 2015_12 FBgn0266314 CR44979 http://flybase.net/reports/FBgn0266314.html non_protein_coding_gene CR44979 16-Dec-15 2015_12 FBgn0065375 l(2)SH1683 lethal (2) SH1683 http://flybase.net/reports/FBgn0065375.html gene l(2)SH2 1683 16-Dec-15 2015_12 "lethal,recessive" FBgn0265609 CR44427 http://flybase.net/reports/FBgn0265609.html non_protein_coding_gene CR44427 16-Dec-15 2015_12 FBgn0039319 CG13659 http://flybase.net/reports/FBgn0039319.html protein_coding_gene "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG13659 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" "viable,fertile" FBgn0021772 ms(3)P122 ms(3)P122 http://flybase.net/reports/FBgn0021772.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0263982 CG43731 http://flybase.net/reports/FBgn0263982.html protein_coding_gene CG43731 16-Dec-15 2015_12 FBgn0011210 shk shank http://flybase.net/reports/FBgn0011210.html gene "0007140=male meiosis, 0007283=spermatogenesis" ms(3)07735 16-Dec-15 2015_12 "meiotic cell cycle defective,male sterile,recessive" "spermatid,Nebenkern" FBgn0014155 e(wa)r "enhancer of white-apricot, recessive" http://flybase.net/reports/FBgn0014155.html gene "enhancer of white-apricot, e(w[a])" 16-Dec-15 2015_12 FBgn0015879 anon-48Ah anon-48Ah http://flybase.net/reports/FBgn0015879.html gene "X, transcript group X" 16-Dec-15 2015_12 FBgn0014204 l(1)16Fk lethal (1) 16Fk http://flybase.net/reports/FBgn0014204.html gene HL-XIII 16-Dec-15 2015_12 lethal FBgn0031414 eys eyes shut http://flybase.net/reports/FBgn0031414.html "FBgn0053955, FBgn0031415, FBgn0031416" protein_coding_gene "0005201=extracellular matrix structural constituent, 0005509=calcium ion binding" "0010378=temperature compensation of the circadian clock, 0042052=rhabdomere development, 0000902=cell morphogenesis" "0005886=plasma membrane, 0009986=cell surface, 0005576=extracellular region, 0005615=extracellular space, 0031513=nonmotile primary cilium" "Spacemaker, Eyes Shut, Spam, MAb21A6, CG33955, 21A6, fibropellin, mAb 21A6, CG15388, CG15389, Eys, spacemaker, agrin-like, EYS, spam, Eyeshut, CT35437, SPAM, mAb21A6, CG7245" "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site, IPR001881=EGF-like calcium-binding domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site" CG33955 16-Dec-15 2015_12 "locomotor rhythm defective,viable,uncoordinated,heat sensitive,locomotor behavior defective,flightless,neurophysiology defective" "photoreceptor cell,eye photoreceptor cell stalk,rhabdomere,ommatidium,rhabdomere of eye photoreceptor cell,conditional,chemical conditional,eye,ocellus retinula cell,ocellus rhabdomere,rhabdomerehs.PB,mechanosensory neuron,heat sensitive,Johnston organ,scolopale" FBgn0053319 CR33319 http://flybase.net/reports/FBgn0053319.html FBgn0032905 pseudogene_attribute CG18078 CR33319 16-Dec-15 2015_12 FBgn0051562 CR31562 http://flybase.net/reports/FBgn0051562.html "FBgn0037407, FBgn0040677" pseudogene_attribute "CG15587, CG31562, CG15588" CR31562 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0065905 l(2)SH0193 lethal (2) SH0193 http://flybase.net/reports/FBgn0065905.html gene l(2)SH2 0193 16-Dec-15 2015_12 "lethal,recessive" FBgn0039350 jigr1 jing interacting gene regulatory 1 http://flybase.net/reports/FBgn0039350.html protein_coding_gene 0044212=transcription regulatory region DNA binding 0010468=regulation of gene expression 0005634=nucleus "JIGR-1, bs29f05.y1, CG17383, JIGR1" IPR006578=MADF domain CG17383 16-Dec-15 2015_12 "neuroanatomy defective,visible,lethal - all die during larval stage,viable,fertile" "embryonic/larval central nervous system,wing,embryonic/larval hemocyte | third instar larval stage" FBgn0005598 yemG3a yema gene 3a http://flybase.net/reports/FBgn0005598.html FBgn0004042 gene "unnamed, yG3a, yT3a" 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage | early , embryonic stage | stage <=8 " " ovary

, organism

" FBgn0016852 l(1)N33 lethal (1) N33 http://flybase.net/reports/FBgn0016852.html gene N33 16-Dec-15 2015_12 "lethal,recessive" FBgn0043062 Tl::Toll-6 Tl::Toll-6 http://flybase.net/reports/FBgn0043062.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0263653 CR43644 http://flybase.net/reports/FBgn0263653.html non_protein_coding_gene CR43644 16-Dec-15 2015_12 FBgn0267435 chp chaoptin http://flybase.net/reports/FBgn0267435.html "FBgn0262131, FBgn0000313" protein_coding_gene "0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0042051=compound eye photoreceptor development, 0042052=rhabdomere development" "0016028=rhabdomere, 0046658=anchored component of plasma membrane, 0035996=rhabdomere microvillus, 0005886=plasma membrane" "mAb24B10, CHP, Chp, Chaoptin, INAD localization-A, chaoptic, MAb24B10, BSH, mAB24B10, MAb 24B10, Chaoptic, 24B10, Mab24B10, Nsp, mAb 24B10, CT5040, Neural-specific-protein, idl-A, CG1744, 516" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype, IPR000225=Armadillo" CG1744 16-Dec-15 2015_12 larval stage && pupal stage " retina

, photoreceptor cell R1--8

, eye-antennal disc

" " larval stage--adult stage , pupal stage&&adult stage , pupal stage , larval stage&&pupal stage , larval stage && pupal stage " " retina

, medulla

, optic lobe

, photoreceptor cell | presumptive

, eye-antennal disc

, lamina

" FBgn0001806 l(1)Mc39 lethal (1) Mc39 http://flybase.net/reports/FBgn0001806.html gene 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,somatic clone" FBgn0011175 l(1)291-53 lethal (1) 291-53 http://flybase.net/reports/FBgn0011175.html FBgn0010199 gene 291-53 16-Dec-15 2015_12 "lethal,recessive,male sterile,visible" wing FBgn0004472 apo altered pattern orientation http://flybase.net/reports/FBgn0004472.html gene apo[S129] 16-Dec-15 2015_12 "visual behavior defective,recessive" FBgn0024565 l(3)L6710 lethal (3) L6710 http://flybase.net/reports/FBgn0024565.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011791 l(3)j4E6 lethal (3) j4E6 http://flybase.net/reports/FBgn0011791.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028942 CG16852 http://flybase.net/reports/FBgn0028942.html "FBgn0032529, FBgn0063294" protein_coding_gene "BcDNA:AT28681, BG:BACR48E02.2" CG16852 16-Dec-15 2015_12 viable FBgn0034251 ND-51L1 NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 1 http://flybase.net/reports/FBgn0034251.html protein_coding_gene "0051287=NAD binding, 0010181=FMN binding, 0008137=NADH dehydrogenase (ubiquinone) activity, 0051539=4 iron, 4 sulfur cluster binding" 0055114=oxidation-reduction process 0005747=mitochondrial respiratory chain complex I "NADH-UBIQUINONE OXIDOREDUCTASE 51 KDA SUBUNIT, NADH:ubiquinone oxidoreductase 51 kDa subunit, NUBM, CG11423" "IPR011537=NADH ubiquinone oxidoreductase, F subunit, IPR001949=NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site, IPR019575=NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain, IPR011538=NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019554=Soluble ligand binding domain" CG11423 16-Dec-15 2015_12 viable FBgn0065599 l(2)SH0875 lethal (2) SH0875 http://flybase.net/reports/FBgn0065599.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052640 CG32640 http://flybase.net/reports/FBgn0052640.html protein_coding_gene 0009408=response to heat "IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site" CG32640 16-Dec-15 2015_12 "viable,fertile" FBgn0004855 RpII15 RNA polymerase II 15kD subunit http://flybase.net/reports/FBgn0004855.html protein_coding_gene "0008270=zinc ion binding, 0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0007067=mitotic nuclear division, 0022008=neurogenesis, 0007095=mitotic G2 DNA damage checkpoint, 0006366=transcription from RNA polymerase II promoter" "0005665=DNA-directed RNA polymerase II, core complex, 0005634=nucleus" "RNAP II, RNA polymerase II 15kd subunit, RNApolII, l(3)88Be, Pol II, RNAP, H5, dRPB9, RNA Pol II, pol II, RpII215, RNA pol II, CG3284, RNA polII, Rpb9, RPII15, polII, PolII, RNA polymerase II, l(3)Z23" "IPR001529=DNA-directed RNA polymerase, M/15kDa subunit, IPR001222=Zinc finger, TFIIS-type, IPR019761=DNA-directed RNA polymerase M, 15kDa subunit, conserved site, IPR012164=DNA-directed RNA polymerase, subunit C11/M/9" CG3284 16-Dec-15 2015_12 "ENSDARG00000040443(polr2i),ENSDARG00000044171" YGL070C(RPB9) WBGene00022400(rpb-9) ENSXETG00000019057(POLR2I) ENSMUSG00000019738(Polr2i) ENSG00000105258(POLR2I) " embryonic stage -- adult stage , adult stage , embryonic stage , larval stage "

ubiquitous "lethal,polyphasic,recessive,wild-type,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "capitellum,ganglion mother cell" DRSC16832 K -1.030864731 1.445908083 -0.478544839 -0.418832344 1.972142923 3.033536975 FBgn0002147 l(2)K513 lethal (2) K513 http://flybase.net/reports/FBgn0002147.html gene 16-Dec-15 2015_12 lethal FBgn0025454 Cyp6g1 Cyp6g1 http://flybase.net/reports/FBgn0025454.html "FBgn0003288, FBgn0067801, FBgn0067802" protein_coding_gene "0020037=heme binding, 0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity" "0017085=response to insecticide, 0046689=response to mercury ion, 0046683=response to organophosphorus, 0046701=insecticide catabolic process, 0046680=response to DDT, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "RI[II], RI[DDT], cyp6g1, Cyp6G1, anon-WO03025223.16, RI, CYP6g1, Resistance to Insecticide on chromosome 2, CYP6-like, Rst(2)DDT, DDT-R, unnamed, cytochrome P450, RDDT, Cyp6gl, Dmel-Cyp6g1, CG8453, CYP6G1, Resistance to Insecticide-DDT, 6g1, anon-WO03025223.17, Cyp6-like, Resistance to DDT" "IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450" CG8453 16-Dec-15 2015_12 "ENSDARG00000037874(LOC558473),ENSDARG00000037873(cyp3c1l2),ENSDARG00000070021(zgc:153269),ENSDARG00000015575(cyp3c1)" YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "viable,fertile,chemical sensitive,chemical resistant,maternal effect" FBgn0043058 Trl::ttk Trl::ttk http://flybase.net/reports/FBgn0043058.html engineered_fusion_gene 16-Dec-15 2015_12 "visible,lethal" eye FBgn0267242 CR45682 http://flybase.net/reports/FBgn0267242.html non_protein_coding_gene CR45682 16-Dec-15 2015_12 FBgn0002864 Mst95EF Male-specific RNA 95EF http://flybase.net/reports/FBgn0002864.html gene mst345 16-Dec-15 2015_12 FBgn0001488 l(1)10Ah lethal (1) 10Ah http://flybase.net/reports/FBgn0001488.html gene l(1)G12 16-Dec-15 2015_12 lethal FBgn0035537 CG11342 http://flybase.net/reports/FBgn0035537.html protein_coding_gene 0008168=methyltransferase activity "IPR024160=Bin3-type S-adenosyl-L-methionine binding domain, IPR025714=Methyltransferase domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR010675=Bicoid-interacting 3" CG11342 16-Dec-15 2015_12 ENSXETG00000020395(BCDIN3D) ENSMUSG00000037525(Bcdin3d) ENSG00000186666(BCDIN3D) viable FBgn0261292 CheB53a Chemosensory protein B 53a http://flybase.net/reports/FBgn0261292.html "FBgn0067310, FBgn0053550, FBgn0034130, FBgn0053457, FBtr0087084, FBpp0086232" protein_coding_gene 0008289=lipid binding "0043695=detection of pheromone, 0007606=sensory perception of chemical stimulus" "0005576=extracellular region, 0005615=extracellular space" "CG16797, unnamed, CG33457, CheB53a, CG33550" CG33550 16-Dec-15 2015_12 FBgn0267002 unc-104 unc-104 ortholog (C. elegans) http://flybase.net/reports/FBgn0267002.html "FBgn0034155, FBgn0086297" protein_coding_gene "0003777=microtubule motor activity, 0008017=microtubule binding, 0005524=ATP binding" "0008089=anterograde axon cargo transport, 0016188=synaptic vesicle maturation, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0032024=positive regulation of insulin secretion, 0051963=regulation of synapse assembly, 0008088=axon cargo transport, 0040012=regulation of locomotion, 0046847=filopodium assembly, 0007411=axon guidance, 0008345=larval locomotory behavior, 0048814=regulation of dendrite morphogenesis, 0048490=anterograde synaptic vesicle transport, 0007528=neuromuscular junction development, 0016192=vesicle-mediated transport, 0048489=synaptic vesicle transport, 0047496=vesicle transport along microtubule" "0030424=axon, 0030425=dendrite, 0005871=kinesin complex, 0005875=microtubule associated complex" "Dunc104, DUNC104, unc-104, immaculate connections, kinesin 3, DmKlp53D, CG8566, Unc-104, KIF1A/1B, unc-104 ortholog, D Uncoordinated Protein 104, DUnc-104, KIF 1B, unc104, bris, bristly, imac, DmDUnc104, KIF1A, Unc104, DmCG8566, Klp53D, Kinesin-3" "IPR022164=Kinesin-like, IPR001849=Pleckstrin homology domain, IPR008984=SMAD/FHA domain, IPR022140=Kinesin-like KIF1-type, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR027640=Kinesin-like protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000253=Forkhead-associated (FHA) domain, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain" CG8566 16-Dec-15 2015_12 "ENSDARG00000037020,ENSDARG00000061817(LOC559468)" WBGene00006831(unc-104) ENSXETG00000012138(KIF1A) "ENSMUSG00000014602(Kif1a),ENSMUSG00000063077(Kif1b)" "ENSG00000130294(KIF1A),ENSG00000054523(KIF1B)" FBgn0040238 Best1 Bestrophin 1 http://flybase.net/reports/FBgn0040238.html "FBgn0037795, FBgn0062053" protein_coding_gene "0072320=volume-sensitive chloride channel activity, 0005254=chloride channel activity, 0005229=intracellular calcium activated chloride channel activity" "0006821=chloride transport, 0006884=cell volume homeostasis, 0009992=cellular water homeostasis" 0005887=integral component of plasma membrane "Dbest, best, anon-WO0118547.380, CG6264, dBest1, dbest1, dmBest1" "IPR000615=Bestrophin, IPR021134=Bestrophin/UPF0187" CG6264 16-Dec-15 2015_12 "WBGene00015286(C01B12.3),WBGene00015288(C01B12.5)" "ENSXETG00000013592(BEST4),ENSXETG00000025368(BC061379.1),ENSXETG00000001407(BEST3),ENSXETG00000006740(BEST1)" "ENSMUSG00000052819(Best2),ENSMUSG00000020169(Best3),ENSMUSG00000037418(Best1)" "ENSG00000039987(BEST2),ENSG00000127325(BEST3),ENSG00000142959(BEST4),ENSG00000167995(BEST1)" "viable,fertile" FBgn0083014 snoRNA:ë¬18S-996 snoRNA:ë¬18S-996 http://flybase.net/reports/FBgn0083014.html snoRNA_gene "Psi 18S-996, psi18s-996, chr3L:245309..245488, CR34630" CR34630 16-Dec-15 2015_12 FBgn0031209 Ir21a Ionotropic receptor 21a http://flybase.net/reports/FBgn0031209.html protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity" 0050907=detection of chemical stimulus involved in sensory perception "0016020=membrane, 0016021=integral component of membrane" "ionotropic receptor 21a, DmelIR21a, CT8983, ir21a, IR21a, CG2657" IPR001320=Ionotropic glutamate receptor CG2657 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable,fertile" FBgn0065804 l(2)SH0398 lethal (2) SH0398 http://flybase.net/reports/FBgn0065804.html gene l(2)SH2 0398 16-Dec-15 2015_12 "lethal,recessive" FBgn0044495 DTD45.11 DTD45.11 http://flybase.net/reports/FBgn0044495.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265960 CR44747 http://flybase.net/reports/FBgn0265960.html non_protein_coding_gene lincRNA.24 CR44747 16-Dec-15 2015_12 FBgn0046711 GIIIA GIIIA http://flybase.net/reports/FBgn0046711.html gene 0004623=phospholipase A2 activity 0005576=extracellular region dGIIIA 16-Dec-15 2015_12 FBgn0004575 Syn Synapsin http://flybase.net/reports/FBgn0004575.html protein_coding_gene "0005524=ATP binding, 0003824=catalytic activity" "0051124=synaptic growth at neuromuscular junction, 0008306=associative learning, 0008049=male courtship behavior, 0071632=optomotor response, 0009408=response to heat, 0008355=olfactory learning, 0048149=behavioral response to ethanol, 0072553=terminal button organization, 0007269=neurotransmitter secretion, 0007613=memory, 0016079=synaptic vesicle exocytosis" "0008021=synaptic vesicle, 0045202=synapse, 0043195=terminal bouton" "syn, SYN1, SYN, CG3985, synapsin, Synapsin1, SYN2, Synapsin I, Dsyn-1" "IPR016185=Pre-ATP-grasp domain, IPR001359=Synapsin, IPR013816=ATP-grasp fold, subdomain 2, IPR020897=Synapsin, pre-ATP-grasp domain, IPR020898=Synapsin, ATP-binding domain, IPR013815=ATP-grasp fold, subdomain 1" CG3985 16-Dec-15 2015_12 "ENSMUSG00000009394(Syn2),ENSMUSG00000059602(Syn3),ENSMUSG00000037217(Syn1)" "ENSG00000008056(SYN1),ENSG00000185666(SYN3),ENSG00000157152(SYN2)" "viable,fertile,learning defective,short lived,locomotor behavior defective,optomotor response defective,jump response defective,chemical resistant,memory defective,courtship behavior defective,male" FBgn0002913 mwi misheld wings http://flybase.net/reports/FBgn0002913.html gene 16-Dec-15 2015_12 "male fertile,viable,good,male,female,reduced,female fertile,visible,recessive" "wing,eye" FBgn0034706 CG11275 http://flybase.net/reports/FBgn0034706.html protein_coding_gene i188 "IPR000210=BTB/POZ domain, IPR011333=POZ domain" CG11275 16-Dec-15 2015_12 DRSC04095 E 0.020832688 0.2044938 -1.748534365 0.048734281 0.331738649 0.094925004 FBgn0029838 CG4666 http://flybase.net/reports/FBgn0029838.html protein_coding_gene IPR029069=HotDog domain CG4666 16-Dec-15 2015_12 "ENSDARG00000059795(si:ch73-52e5.1),ENSDARG00000037345(si:ch73-52e5.2)" ENSMUSG00000056665(4930572J05Rik) ENSG00000130193(C8orf55) viable FBgn0021874 Nle Notchless http://flybase.net/reports/FBgn0021874.html FBgn0042663 protein_coding_gene 0005112=Notch binding 0007219=Notch signaling pathway "l(2)k13714, CG2863, anon-WO0026364, notchless" "IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR012972=NLE, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR001632=G-protein, beta subunit" CG2863 16-Dec-15 2015_12 ENSDARG00000057105(nle1) YCR072C(RSA4) WBGene00021074(W07E6.2) ENSXETG00000013488(NLE1) ENSMUSG00000020692(Nle1) ENSG00000073536(NLE1) "lethal,recessive,viable,male sterile,wild-type,partially lethal - majority die,visible" "microchaeta,trichogen cell,mesothoracic tergum,wing hair,supernumerary" FBgn0024654 l(2)k08139 lethal (2) k08139 http://flybase.net/reports/FBgn0024654.html gene 81/39 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0027617 CG5808 http://flybase.net/reports/FBgn0027617.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003755=peptidyl-prolyl cis-trans isomerase activity, 0003676=nucleic acid binding" "0006457=protein folding, 0022008=neurogenesis, 0000413=protein peptidyl-prolyl isomerization, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "UKL, cg5808, BcDNA:GH01073" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000=Cyclophilin-like domain, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR000504=RNA recognition motif domain" CG5808 16-Dec-15 2015_12 ENSDARG00000043854(ppil4) WBGene00000890(sig-7) ENSXETG00000021385(ppil4) ENSMUSG00000015757(Ppil4) ENSG00000131013(PPIL4) "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "adult thorax,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0015959 l(2)35Fg lethal (2) 35Fg http://flybase.net/reports/FBgn0015959.html gene 0048515=spermatid differentiation 16-Dec-15 2015_12 "lethal,recessive,male sterile" FBgn0029755 Sas10 Something about silencing 10 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0029755.html FBgn0029077 protein_coding_gene 0022008=neurogenesis "Sas10, sas10, CG4202, dSAS10, sas-10, l(1)G0106" "IPR007146=Sas10/Utp3/C1D, IPR018972=Sas10 C-terminal domain" CG4202 16-Dec-15 2015_12 ENSDARG00000056720(zgc:92127) YDL153C(SAS10) WBGene00011311(T01B7.5) ENSXETG00000026859(UTP3) ENSMUSG00000070697(Utp3) ENSG00000132467(UTP3) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,partially lethal - majority die,visible,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,trichogen cell" FBgn0085330 CG34301 http://flybase.net/reports/FBgn0085330.html protein_coding_gene CG34301 16-Dec-15 2015_12 FBgn0061020 l(3)S025266 lethal (3) S025266 http://flybase.net/reports/FBgn0061020.html gene 0252/66 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0034224 insb insensible http://flybase.net/reports/FBgn0034224.html protein_coding_gene 0045746=negative regulation of Notch signaling pathway 0005634=nucleus CG6520 CG6520 16-Dec-15 2015_12 visible "wing,macrochaeta" DRSC24404 K -0.385707856 0.006611337 0.490970354 0.514074723 2.713528397 1.767185721 FBgn0037606 CG8032 http://flybase.net/reports/FBgn0037606.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR002937=Amine oxidase CG8032 16-Dec-15 2015_12 "ENSDARG00000036967,ENSDARG00000003380(si:dkey-275b16.2)" "WBGene00016061(C24G6.6),WBGene00000139(amx-3)" "ENSXETG00000017992(smox),ENSXETG00000022139(paox)" "ENSMUSG00000027333(Smox),ENSMUSG00000025464(Paox)" "ENSG00000088826(SMOX),ENSG00000148832(PAOX)" viable FBgn0051480 tRNA:CR31480 transfer RNA:CR31480 http://flybase.net/reports/FBgn0051480.html "FBgn0011990, FBgn0023420, FBgn0060041" tRNA_gene "0033440=ACG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:thr4:93A, tRNA[[Thr]], tRNA:T3:93AB, CR31480, AE002708.trna23-ThrCGT, tRNA:T4:93A, tRNA:T:CGT:AE002708-a, tRNA:thr4:93A, tRNA[Thr][[3]], tRNA[Thr][[4]], chr3R.trna29-ThrCGT" CR31480 16-Dec-15 2015_12 FBgn0085380 CG34351 http://flybase.net/reports/FBgn0085380.html "FBgn0031625, FBgn0031624" protein_coding_gene "CG11928, CG15633, ORE-3" IPR026512=RGS7BP/RGS9BP family CG34351 16-Dec-15 2015_12 ENSXETG00000000463(RGS7BP) ENSMUSG00000021719(Rgs7bp) viable FBgn0030666 CG12708 http://flybase.net/reports/FBgn0030666.html protein_coding_gene CG12708 16-Dec-15 2015_12 "viable,fertile" FBgn0031302 CG14340 http://flybase.net/reports/FBgn0031302.html protein_coding_gene 0016192=vesicle-mediated transport 0016020=membrane "IPR010989=t-SNARE, IPR026512=RGS7BP/RGS9BP family" CG14340 16-Dec-15 2015_12 ENSXETG00000000463(RGS7BP) ENSMUSG00000021719(Rgs7bp) FBgn0015957 l(1)6Fd lethal (1) 6Fd http://flybase.net/reports/FBgn0015957.html gene l 16-Dec-15 2015_12 FBgn0263236 SP1029 SP1029 http://flybase.net/reports/FBgn0263236.html "FBgn0040282, FBgn0039658, FBgn0014996" protein_coding_gene "0004046=aminoacylase activity, 0008270=zinc ion binding, 0008237=metallopeptidase activity, 0004177=aminopeptidase activity" "0006508=proteolysis, 0046331=lateral inhibition" "pathless, ptl, CG11956, ptls" "IPR024571=ERAP1-like C-terminal domain, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase" CG11956 16-Dec-15 2015_12 FBgn0027172 l(2)B1 lethal (2) B1 http://flybase.net/reports/FBgn0027172.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0002334 l(3)87Bb lethal (3) 87Bb http://flybase.net/reports/FBgn0002334.html gene "ck14, l(3)ck14" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0034936 CG2970 http://flybase.net/reports/FBgn0034936.html protein_coding_gene 0016020=membrane SD03319p "IPR001972=Stomatin family, IPR001107=Band 7 protein" CG2970 16-Dec-15 2015_12 WBGene00006061(stl-1) ENSXETG00000025791(stoml2) ENSMUSG00000028455(Stoml2) ENSG00000165283(STOML2) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0264832 CG44040 http://flybase.net/reports/FBgn0264832.html protein_coding_gene CG44040 16-Dec-15 2015_12 FBgn0065356 l(2)SH1760 lethal (2) SH1760 http://flybase.net/reports/FBgn0065356.html gene l(2)SH2 1760 16-Dec-15 2015_12 "lethal,recessive" FBgn0052446 Atox1 http://flybase.net/reports/FBgn0052446.html FBgn0037112 protein_coding_gene 0046872=metal ion binding "0055070=copper ion homeostasis, 0030001=metal ion transport" "CG32446, DmAtox1, CG12562" "IPR006121=Heavy metal-associated domain, HMA" CG32446 16-Dec-15 2015_12 YNL259C(ATX1) WBGene00000835(cuc-1) ENSXETG00000026565(atox1) ENSMUSG00000018585(Atox1) ENSG00000177556(ATOX1) "wild-type,partially lethal - majority die,fertile,lethal,chemical conditional,viable" FBgn0060633 l(3)S085203 lethal (3) S085203 http://flybase.net/reports/FBgn0060633.html gene 0852/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0016858 l(1)N5 lethal (1) N5 http://flybase.net/reports/FBgn0016858.html gene N5 16-Dec-15 2015_12 "lethal,recessive" FBgn0027211 l(1)G0355 lethal (1) G0355 http://flybase.net/reports/FBgn0027211.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0011535 l(3)00945 lethal (3) 00945 http://flybase.net/reports/FBgn0011535.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028121 l(3)S059706 lethal (3) S059706 http://flybase.net/reports/FBgn0028121.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052359 tRNA:CR32359 transfer RNA:CR32359 http://flybase.net/reports/FBgn0052359.html FBgn0060157 tRNA_gene 0033420=CUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002602.trna9-LeuCAG, CR32359, chr3L.trna43-LeuCAG, tRNA:L:CAG:AE002602-e" CR32359 16-Dec-15 2015_12 FBgn0011212 bet betel http://flybase.net/reports/FBgn0011212.html gene 0007286=spermatid development ms(3)04066 16-Dec-15 2015_12 "male sterile,recessive" FBgn0032746 CG10470 http://flybase.net/reports/FBgn0032746.html FBgn0005568 protein_coding_gene 0016020=membrane "B2, transcription unit 37B2, TuB2, TU37B2, TUB2, anon-37B-2" "IPR002809=Protein of unknown function DUF106, transmembrane, IPR008559=Uncharacterised conserved protein UCP023322, transmembrane eukaryotic" CG10470 16-Dec-15 2015_12 ENSDARG00000069099(tmco1) WBGene00009045(F22B5.10) ENSXETG00000017353(tmcc4) ENSMUSG00000052428(Tmco1) ENSG00000143183(TMCO1) viable FBgn0266568 yar yellow-achaete intergenic RNA http://flybase.net/reports/FBgn0266568.html "FBgn0261559, FBgn0042674" non_protein_coding_gene "0045187=regulation of circadian sleep/wake cycle, sleep" 0005737=cytoplasm "anon-1Be, CR42744, y-ac intergenic RNA" CR42744 16-Dec-15 2015_12 FBgn0029996 UbcE2H Ubiquitin conjugating enzyme E2H http://flybase.net/reports/FBgn0029996.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0046331=lateral inhibition, 0000209=protein polyubiquitination" "Ubc-E2H, ubcE2h, dUbc-E2H, UbcDE2H, CG2257, UbcE2H, Ubc-E2Hs" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2, IPR023313=Ubiquitin-conjugating enzyme, active site" CG2257 16-Dec-15 2015_12 ENSDARG00000000019(ube2h) YEL012W(UBC8) WBGene00006705(ubc-8) ENSXETG00000025415(ube2h) ENSMUSG00000039159(Ube2h) ENSG00000186591(UBE2H) "lethal,recessive,viable,visible,body color defective,stress response defective" "chaeta,supernumerary,mesothoracic tergum" DRSC18221 K 1.108765544 -1.432740002 -0.090545954 0.468259198 1.716623345 0.861211737 FBgn0032154 mtDNA-helicase mitochondrial DNA helicase http://flybase.net/reports/FBgn0032154.html protein_coding_gene "0043139=5'-3' DNA helicase activity, 0003690=double-stranded DNA binding, 0051537=2 iron, 2 sulfur cluster binding, 0005524=ATP binding, 0003697=single-stranded DNA binding" "0000002=mitochondrial genome maintenance, 0006264=mitochondrial DNA replication, 0051260=protein homooligomerization" "0005739=mitochondrion, 0042645=mitochondrial nucleoid" "d-mtDNA helicase, CG5924, Twinkle, mitochondrial DNA helicase, mtDNA helicase" "IPR027032=Twinkle-like protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007694=DNA helicase, DnaB-like, C-terminal" CG5924 16-Dec-15 2015_12 WBGene00018514(F46G11.1) ENSXETG00000015205(C10orf2) ENSMUSG00000025209(Peo1) ENSG00000107815(C10orf2) "cell growth defective,viable,fertile,increased cell death,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing disc | third instar larval stage,wing disc,posterior compartment | third instar larval stage" FBgn0082961 snoRNA:ë¬28S-3385b snoRNA:ë¬28S-3385b http://flybase.net/reports/FBgn0082961.html snoRNA_gene "CR34607, psi28s-3385b" CR34607 16-Dec-15 2015_12 FBgn0266648 CR45155 http://flybase.net/reports/FBgn0266648.html non_protein_coding_gene CR45155 16-Dec-15 2015_12 FBgn0033523 CG12895 http://flybase.net/reports/FBgn0033523.html FBgn0047132 protein_coding_gene "0018293=protein-FAD linkage, 0006121=mitochondrial electron transport, succinate to ubiquinone" 0005739=mitochondrion BcDNA:RE29446 "IPR005631=Flavinator of succinate dehydrogenase, IPR028882=Succinate dehydrogenase assembly factor 2, mitochondrial" CG12895 16-Dec-15 2015_12 ENSDARG00000062971(zgc:163000) YOL071W(EMI5) WBGene00013269(Y57A10A.29) ENSXETG00000006724(SDHAF2) ENSMUSG00000024668(Sdhaf2) ENSG00000167985(SDHAF2) "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0041125 l(2)45Al lethal (2) 45Al http://flybase.net/reports/FBgn0041125.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0027336 l(1)40b lethal (1) 40b http://flybase.net/reports/FBgn0027336.html gene 16-Dec-15 2015_12 lethal FBgn0025681 CG3558 http://flybase.net/reports/FBgn0025681.html FBgn0031487 protein_coding_gene "c4.3, LD23852, BEST:LD23852, FBgn0025681" IPR019384=Retinoic acid induced 16-like protein CG3558 16-Dec-15 2015_12 "ENSDARG00000060029(fam160b2),ENSDARG00000060168(fam160b1),ENSDARG00000015007" WBGene00015485(C05D11.8) "ENSXETG00000009392(FAM160A1),ENSXETG00000010517(FAM160A2)" "ENSMUSG00000051000(Fam160a1),ENSMUSG00000044465(Fam160a2)" ENSG00000051009(FAM160A2) FBgn0259162 RunxB http://flybase.net/reports/FBgn0259162.html "FBgn0031121, FBgn0031122" protein_coding_gene "0005524=ATP binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG15455, CG42267, CG15454" "IPR012346=p53/RUNT-type transcription factor, DNA-binding domain, IPR000040=Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967=p53-like transcription factor, DNA-binding, IPR013524=Runt domain" CG42267 16-Dec-15 2015_12 "ENSDARG00000040261(runx2a),ENSDARG00000059233(runx2b),ENSDARG00000052826(runx3)" WBGene00004393(rnt-1) "ENSXETG00000014140(RUNX1),ENSXETG00000001397()" ENSG00000124813(RUNX2) FBgn0011055 l(1)Q8 lethal (1) Q8 http://flybase.net/reports/FBgn0011055.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0028657 anon-1Ca anon-1Ca http://flybase.net/reports/FBgn0028657.html gene X 16-Dec-15 2015_12 FBgn0082620 S(CycEJP)47S8 S(CycEJP)47S8 http://flybase.net/reports/FBgn0082620.html gene 47S8 16-Dec-15 2015_12 "lethal,recessive" FBgn0037877 CG6689 http://flybase.net/reports/FBgn0037877.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus dmCG6689 "IPR007087=Zinc finger, C2H2, IPR006612=Zinc finger, C2CH-type, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG6689 16-Dec-15 2015_12 WBGene00004335(ref-2) "partially lethal - majority die,some die during pupal stage" FBgn0260467 CG7071 http://flybase.net/reports/FBgn0260467.html "FBgn0038949, FBan0007071, FBgn0063677" protein_coding_gene 0012505=endomembrane system "BcDNA:RE40914, Dromel_CG7071_FBtr0084211_mORF" "IPR021013=ATPase, vacuolar ER assembly factor, Vma12" CG7071 16-Dec-15 2015_12 FBgn0013532 l(2)35Ab lethal (2) 35Ab http://flybase.net/reports/FBgn0013532.html gene 16-Dec-15 2015_12 lethal FBgn0038523 CG7587 http://flybase.net/reports/FBgn0038523.html protein_coding_gene CG7587 16-Dec-15 2015_12 viable FBgn0060939 l(3)S040428b lethal (3) S040428b http://flybase.net/reports/FBgn0060939.html gene 0404/28 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0032360 CG14926 http://flybase.net/reports/FBgn0032360.html protein_coding_gene bs34f02.y1 CG14926 16-Dec-15 2015_12 viable FBgn0001718 l(1)ESHS39 lethal (1) ESHS39 http://flybase.net/reports/FBgn0001718.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038894 CG15497 http://flybase.net/reports/FBgn0038894.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG15497 16-Dec-15 2015_12 viable FBgn0032827 CG10481 http://flybase.net/reports/FBgn0032827.html protein_coding_gene 0016021=integral component of membrane "IPR004342=EXS, C-terminal, IPR004331=SPX domain" CG10481 16-Dec-15 2015_12 YIL047C(SYG1) viable FBgn0037621 M1BP Motif 1 Binding Protein http://flybase.net/reports/FBgn0037621.html protein_coding_gene "0000979=RNA polymerase II core promoter sequence-specific DNA binding, 0008270=zinc ion binding" "0051123=RNA polymerase II transcriptional preinitiation complex assembly, 0046579=positive regulation of Ras protein signal transduction, 0007095=mitotic G2 DNA damage checkpoint, 0070374=positive regulation of ERK1 and ERK2 cascade" 0005634=nucleus CG9797 "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG9797 16-Dec-15 2015_12 "ENSDARG00000071720,ENSDARG00000071723,ENSDARG00000071714(si:dkey-20i20.5),ENSDARG00000071712,ENSDARG00000071713,ENSDARG00000071719(si:dkey-20i20.2),ENSDARG00000071716,ENSDARG00000071846,ENSDARG00000071812,ENSDARG00000071811(si:dkey-4c15.6),ENSDARG00000071829,ENSDARG00000071838,ENSDARG00000071819,ENSDARG00000071791,ENSDARG00000071792,ENSDARG00000052346,ENSDARG00000021484,ENSDARG00000071767(LOC100150655),ENSDARG00000071815(LOC100150260),ENSDARG00000071580,ENSDARG00000040146,ENSDARG00000071833,ENSDARG00000044847(zgc:171599),ENSDARG00000022905,ENSDARG00000071820,ENSDARG00000071858,ENSDARG00000071725(zgc:174919),ENSDARG00000038478(LOC100150696)" WBGene00010770(K11D2.4) FBgn0052383 sphinx1 sphinx1 http://flybase.net/reports/FBgn0052383.html FBgn0035783 protein_coding_gene 0004252=serine-type endopeptidase activity "0045752=positive regulation of Toll signaling pathway, 0006508=proteolysis, 0050832=defense response to fungus, 0050830=defense response to Gram-positive bacterium, 0050829=defense response to Gram-negative bacterium, 0032504=multicellular organism reproduction, 0045087=innate immune response" 0005576=extracellular region "Sphinx-1, CG8555, SPH194, Sphinx1, CG32383" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG32383 16-Dec-15 2015_12 "immune response defective,partially lethal - majority die,some die during pupal stage" FBgn0052413 CG32413 http://flybase.net/reports/FBgn0052413.html FBgn0035646 protein_coding_gene CG10487 IPR007484=Peptidase M28 CG32413 16-Dec-15 2015_12 viable FBgn0022699 D19B D19B http://flybase.net/reports/FBgn0022699.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "d19b, CG10270" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG10270 16-Dec-15 2015_12 WBGene00004773(sem-4) viable FBgn0027553 NELF-B NELF-B http://flybase.net/reports/FBgn0027553.html "FBgn0029956, FBgn0052721" protein_coding_gene 0003723=RNA binding "0045944=positive regulation of transcription from RNA polymerase II promoter, 0034244=negative regulation of transcription elongation from RNA polymerase II promoter, 0007070=negative regulation of transcription from RNA polymerase II promoter during mitosis, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0017053=transcriptional repressor complex, 0032021=NELF complex, 0005634=nucleus" "BcDNA:GH10333, CG12152, CG32721, NELF" IPR010405=Cofactor of BRCA1 CG32721 16-Dec-15 2015_12 ENSDARG00000035505(cobra1) ENSXETG00000000383(Q5I0A8_XENTR) ENSMUSG00000013465(Cobra1) ENSG00000188986(COBRA1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0010614 l(2)06250 lethal (2) 06250 http://flybase.net/reports/FBgn0010614.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0086040 snoRNA:Me28S-A3365 http://flybase.net/reports/FBgn0086040.html snoRNA_gene "Me28S-Am3365, CR34669" CR34669 16-Dec-15 2015_12 FBgn0001574 l(1)63 lethal (1) 63 http://flybase.net/reports/FBgn0001574.html gene tsl(1)63 16-Dec-15 2015_12 "visible,recessive,heat sensitive,male sterile,lethal,male" "mesothoracic tarsal bristle,heat sensitive,mesothoracic tarsal bristle longitudinal row 8,mesothoracic tarsal bristle longitudinal row 1,spermatocyte,metatarsus" FBgn0023136 WppG White prepupal locus G http://flybase.net/reports/FBgn0023136.html gene 35 16-Dec-15 2015_12 FBgn0010767 l(3)02094 lethal (3) 02094 http://flybase.net/reports/FBgn0010767.html gene 0003729=mRNA binding "0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus" L(3)02094 16-Dec-15 2015_12 "lethal,recessive" FBgn0086059 snoRNA:Me18S-C1280 http://flybase.net/reports/FBgn0086059.html snoRNA_gene "CR34688, Me18S-Cm1280" CR34688 16-Dec-15 2015_12 FBgn0036009 Or67a Odorant receptor 67a http://flybase.net/reports/FBgn0036009.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "DOR84, CG12526, odorant receptor 67a, 67a, DmOR67a, 67B.1" "IPR004117=Olfactory receptor, Drosophila" CG12526 16-Dec-15 2015_12 viable FBgn0003397 sho shovel http://flybase.net/reports/FBgn0003397.html gene 16-Dec-15 2015_12 viable wing FBgn0020576 anon-59Ci anon-59Ci http://flybase.net/reports/FBgn0020576.html gene 16-Dec-15 2015_12 FBgn0267315 CR45751 http://flybase.net/reports/FBgn0267315.html non_protein_coding_gene CR45751 16-Dec-15 2015_12 FBgn0002684 mat(3)3 maternal lethal 3 http://flybase.net/reports/FBgn0002684.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,heat sensitive,some die during embryonic stage" "pole cell,heat sensitive,stage 5 embryo,dorsal,posterior,embryonic ventral nervous system" FBgn0038200 CG9920 http://flybase.net/reports/FBgn0038200.html "FBgn0044582, FBgn0045814" protein_coding_gene 0051082=unfolded protein binding "0006457=protein folding, 0006458='de novo' protein folding" 0005759=mitochondrial matrix "BEST:GH20473, anon-WO0140519.48" "IPR011032=GroES-like, IPR020818=Chaperonin Cpn10" CG9920 16-Dec-15 2015_12 ENSDARG00000056167(hspe1) YOR020C(HSP10) WBGene00021248(Y22D7AL.10) ENSXETG00000007510(hspe1) "ENSMUSG00000073676(Hspe1),ENSMUSG00000049246(Hspe1-rs1)" "ENSG00000115541(HSPE1),ENSG00000217897" "viable,visible" trichogen cell FBgn0037014 CG13251 http://flybase.net/reports/FBgn0037014.html protein_coding_gene CG13251 16-Dec-15 2015_12 ENSMUSG00000046753(Ccdc66) viable FBgn0004473 ant antennaless http://flybase.net/reports/FBgn0004473.html gene 16-Dec-15 2015_12 "visible,recessive" antenna FBgn0032446 CG5780 http://flybase.net/reports/FBgn0032446.html protein_coding_gene "0035721=intraciliary retrograde transport, 0060271=cilium morphogenesis" 0030991=intraciliary transport particle A IFT43 IPR029302=Intraflagellar transport protein 43 CG5780 16-Dec-15 2015_12 ENSXETG00000013218(TNeu143e16.1) ENSMUSG00000007867(1700019E19Rik) ENSG00000119650(IFT43) FBgn0001875 l(1)XN82a lethal (1) XN82a http://flybase.net/reports/FBgn0001875.html gene 16-Dec-15 2015_12 FBgn0015314 Tahiti Tahiti http://flybase.net/reports/FBgn0015314.html region 16-Dec-15 2015_12 FBgn0004380 Klp64D Kinesin-like protein at 64D http://flybase.net/reports/FBgn0004380.html protein_coding_gene "0005524=ATP binding, 0003777=microtubule motor activity, 0008017=microtubule binding" "0007018=microtubule-based movement, 0030177=positive regulation of Wnt signaling pathway, 0035058=nonmotile primary cilium assembly, 0030951=establishment or maintenance of microtubule cytoskeleton polarity, 0007411=axon guidance, 0007288=sperm axoneme assembly, 0007608=sensory perception of smell, 0048812=neuron projection morphogenesis, 0007605=sensory perception of sound, 0008089=anterograde axon cargo transport" "0005886=plasma membrane, 0005769=early endosome, 0005871=kinesin complex, 0005912=adherens junction, 0030054=cell junction, 0005929=cilium" "KIF3A, Klp 64D, KIF 3A, KLP4, KLP64D, CG10642, kinesin-2, Kinesin-2, klp64D, Klp4, DmKlp64D, Kif3A, KLP64Ddm" "IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10642 16-Dec-15 2015_12 "ENSDARG00000071646,ENSDARG00000009850" YEL061C(CIN8) WBGene00002230(klp-20) ENSXETG00000004164(KIF3A) ENSMUSG00000018395(Kif3a) ENSG00000131437(KIF3A) " adult stage , adult stage | female " " head

, ovary

" "lethal,recessive,hypoactive,uncoordinated,neuroanatomy defective,neurophysiology defective,auditory perception defective,female,viable" "scolopidial cilium,Johnston's organ & scolopidial cilium,cilium & cell,sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,cilium,Johnston organ,scolopidial cilium & Johnston's organ,axonelav.PLu" FBgn0266864 CR45325 http://flybase.net/reports/FBgn0266864.html non_protein_coding_gene CR45325 16-Dec-15 2015_12 FBgn0039461 CG5500 http://flybase.net/reports/FBgn0039461.html protein_coding_gene "IPR019180=Oxidoreductase-like, N-terminal" CG5500 16-Dec-15 2015_12 YPL107W() ENSG00000204237(C17orf90) "fertile,viable,partially lethal - majority die,some die during pupal stage" FBgn0001834 l(1)ts538 lethal (1) ts538 http://flybase.net/reports/FBgn0001834.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0011950 tRNA:R:12Ec transfer RNA:arg:12Ec http://flybase.net/reports/FBgn0011950.html "FBgn0011947, FBgn0052619, FBgn0060080" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033431=CGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chrX.trna10-ArgTCG, AE002593.trna6-ArgTCG, tRNA:R:TCG:AE002593-d, tRNA:R1, transfer RNA:arg1, tRNA:arg1, tRNA[arg], CR32619, tRNA-Arg, tRNA:arg12Ec" CR32619 16-Dec-15 2015_12 FBgn0267207 CR45647 http://flybase.net/reports/FBgn0267207.html non_protein_coding_gene CR45647 16-Dec-15 2015_12 FBgn0259519 GG01518 http://flybase.net/reports/FBgn0259519.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033234 MFS12 Major Facilitator Superfamily Transporter 12 http://flybase.net/reports/FBgn0033234.html FBgn0044526 protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "anon-WO0140519.99, CG8791" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG8791 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,fertile" FBgn0040919 CG15895 http://flybase.net/reports/FBgn0040919.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036032 CG16711 http://flybase.net/reports/FBgn0036032.html protein_coding_gene CG16711 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0069052 COM centre organisateur de mobilisation http://flybase.net/reports/FBgn0069052.html gene 16-Dec-15 2015_12 FBgn0003168 Pur-r Purine-resistant http://flybase.net/reports/FBgn0003168.html gene PurR 16-Dec-15 2015_12 chemical resistant FBgn0017363 l(3)89Bq lethal (3) 89Bq http://flybase.net/reports/FBgn0017363.html gene l(3)89Bo 16-Dec-15 2015_12 "lethal,recessive" FBgn0005149 l(2)G78 lethal (2) G78 http://flybase.net/reports/FBgn0005149.html gene 16-Dec-15 2015_12 lethal FBgn0034961 CG3163 http://flybase.net/reports/FBgn0034961.html protein_coding_gene IPR006578=MADF domain CG3163 16-Dec-15 2015_12 viable FBgn0033029 Not3 http://flybase.net/reports/FBgn0033029.html protein_coding_gene 0005515=protein binding "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0017148=negative regulation of translation, 0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0006402=mRNA catabolic process, 0006351=transcription, DNA-templated" "0005634=nucleus, 0005737=cytoplasm, 0030014=CCR4-NOT complex" "CG8426, NOT3.5, NOT3, l(2)NC136, lethal (2) NC136, not3/5, lethal(2)NC136, Not3, NOT3/5, CNOT3, not3" "IPR007207=CCR4-Not complex component, Not N-terminal domain, IPR007282=NOT2/NOT3/NOT5, IPR012270=CCR4-NOT complex, subunit 3/ 5" CG8426 16-Dec-15 2015_12 ENSDARG00000007135(cnot3a) YPR072W(NOT5) ENSXETG00000003166(CNOT3) ENSMUSG00000035632(Cnot3) ENSG00000088038(CNOT3) "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC04908 IE -0.439208659 -4.097402297 -2.378796068 -1.774960794 0.082698651 -0.643598999 FBgn0011971 tRNA:S2b:88A transfer RNA:ser2b:88A http://flybase.net/reports/FBgn0011971.html "FBgn0011968, FBgn0011969, FBgn0051476, FBgn0060055" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033446=AGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:ser, tRNA[Ser][[2b]], transfer RNA:ser2b, tRNA:ser2b:88A, tRNA:S:GCT:AE002708-e, tRNA:S, tRNA:ser2b, CR31476, tRNA:ser, tRNA:S2b, chr3R.trna59-SerGCT, AE002708.trna53-SerGCT, tRNA[[Ser]]" CR31476 16-Dec-15 2015_12 FBgn0085829 CR42196 http://flybase.net/reports/FBgn0085829.html FBan0042196 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0001427 l(1)6Ed lethal (1) 6Ed http://flybase.net/reports/FBgn0001427.html gene "jnL2, l(1)jnL2, JNL2" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0014073 Tie Tie-like receptor tyrosine kinase http://flybase.net/reports/FBgn0014073.html protein_coding_gene "0004713=protein tyrosine kinase activity, 0005524=ATP binding" "0060548=negative regulation of cell death, 0006468=protein phosphorylation, 2000683=regulation of cellular response to X-ray, 0007298=border follicle cell migration, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0018108=peptidyl-tyrosine phosphorylation" 0005887=integral component of plasma membrane "CG7525, tyrosine kinase, RTK, tie, DPR1, Tyrosine kinase with Ig and epidermal growth factor homology domain" "IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG7525 16-Dec-15 2015_12 "viable,radiation sensitive,dominant" DRSC08702 I 1.634500123 0.021945634 1.240433087 -0.259324327 -0.153639017 -0.926267686 FBgn0260484 HIP Hsc/Hsp70-interacting protein http://flybase.net/reports/FBgn0260484.html "FBgn0052789, FBgn0025274" protein_coding_gene "0051087=chaperone binding, 0030544=Hsp70 protein binding, 0031072=heat shock protein binding" 0070389=chaperone cofactor-dependent protein refolding "0043234=protein complex, 0005737=cytoplasm, 0005829=cytosol" "HIP, anon-fast-evolving-1A9, CG32789, anon-EST:fe1A9" "IPR019734=Tetratricopeptide repeat, IPR013105=Tetratricopeptide repeat 2, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR006636=Heat shock chaperonin-binding" CG32789 16-Dec-15 2015_12 FBgn0065953 l(2)SH0067 lethal (2) SH0067 http://flybase.net/reports/FBgn0065953.html gene l(2)SH2 0067 16-Dec-15 2015_12 "lethal,recessive" FBgn0004818 fs(2)ltoDC37 female sterile (2) ltoDC37 http://flybase.net/reports/FBgn0004818.html gene 0007300=ovarian nurse cell to oocyte transport 16-Dec-15 2015_12 female sterile FBgn0013769 CypB Cyclophylin B http://flybase.net/reports/FBgn0013769.html gene DCyp-B 16-Dec-15 2015_12 FBgn0040551 CG11686 http://flybase.net/reports/FBgn0040551.html FBgn0047032 protein_coding_gene BcDNA:RH19248 CG11686 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0065170 l(3)SH026 lethal (3) SH026 http://flybase.net/reports/FBgn0065170.html gene l(2)SH3 026 16-Dec-15 2015_12 "lethal,recessive" FBgn0263051 CG43346 http://flybase.net/reports/FBgn0263051.html "FBgn0032926, FBan0009243" protein_coding_gene CG9243 CG43346 16-Dec-15 2015_12 embryonic/larval hemocyte | third instar larval stage FBgn0000771 fs(1)A1140 female sterile (1) A1140 http://flybase.net/reports/FBgn0000771.html gene fs(1)1140 16-Dec-15 2015_12 "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "blastoderm embryo,gastrula embryo" FBgn0265069 CR44180 http://flybase.net/reports/FBgn0265069.html non_protein_coding_gene CR44180 16-Dec-15 2015_12 FBgn0065218 l(2)SH2238 lethal (2) SH2238 http://flybase.net/reports/FBgn0065218.html gene l(2)SH2 2238 16-Dec-15 2015_12 "lethal,recessive" FBgn0052033 CG32033 http://flybase.net/reports/FBgn0052033.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060528 l(3)S101710 lethal (3) S101710 http://flybase.net/reports/FBgn0060528.html gene 1017/10 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0085808 CR41591 http://flybase.net/reports/FBgn0085808.html FBan0041591 rRNA_gene CR41591 16-Dec-15 2015_12 FBgn0014050 Su(tor)2-28 Su(tor)2-28 http://flybase.net/reports/FBgn0014050.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0032464 Vha68-3 Vacuolar H+ ATPase 68kD subunit 3 http://flybase.net/reports/FBgn0032464.html protein_coding_gene "0005524=ATP binding, 0046961=proton-transporting ATPase activity, rotational mechanism" "0015991=ATP hydrolysis coupled proton transport, 0046034=ATP metabolic process" "0033176=proton-transporting V-type ATPase complex, 0000221=vacuolar proton-transporting V-type ATPase, V1 domain" "Vacuolar H[+] ATPase subunit 68-3, CG5075, vha67-3, vha68-3, Vha68" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR024034=ATPase, F1 complex beta subunit/V1 complex, C-terminal, IPR022878=V-type ATP synthase catalytic alpha chain, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain, IPR005725=ATPase, V1 complex, subunit A, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal" CG5075 16-Dec-15 2015_12 viable FBgn0028617 l(2)35Ch lethal (2) 35Ch http://flybase.net/reports/FBgn0028617.html gene 16-Dec-15 2015_12 FBgn0033018 CG10453 http://flybase.net/reports/FBgn0033018.html protein_coding_gene 16-Dec-15 2015_12 FBgn0069298 amfos amigo de fos http://flybase.net/reports/FBgn0069298.html gene 0007391=dorsal closure 16-Dec-15 2015_12 FBgn0020356 anon-2Da anon-2Da http://flybase.net/reports/FBgn0020356.html gene "2D3, unnamed" 16-Dec-15 2015_12 FBgn0053284 CG33284 http://flybase.net/reports/FBgn0053284.html FBgn0045345 protein_coding_gene NEST:bs10b10 CG33284 16-Dec-15 2015_12 FBgn0033484 CG2269 http://flybase.net/reports/FBgn0033484.html FBgn0062218 protein_coding_gene anon-WO0118547.141 CG2269 16-Dec-15 2015_12 FBgn0264633 bulgy bulgy http://flybase.net/reports/FBgn0264633.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040782 CG12827 http://flybase.net/reports/FBgn0040782.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039597 CG9997 http://flybase.net/reports/FBgn0039597.html protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0006508=proteolysis, 0046008=regulation of female receptivity, post-mating, 0046692=sperm competition, 0008104=protein localization" 0005615=extracellular space "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG9997 16-Dec-15 2015_12 "mating rhythm defective,viable" FBgn0265166 CR44235 http://flybase.net/reports/FBgn0265166.html non_protein_coding_gene CR44235 16-Dec-15 2015_12 FBgn0013316 Pcp15 Pupal-cuticle-protein-15kD http://flybase.net/reports/FBgn0013316.html gene 16-Dec-15 2015_12 FBgn0034940 CG16787 http://flybase.net/reports/FBgn0034940.html protein_coding_gene IPR018790=Protein of unknown function DUF2358 CG16787 16-Dec-15 2015_12 WBGene00007760(C27B7.2) ENSXETG00000027932(BC087624.1) "lethal - all die before end of pupal stage,some die during pupal stage,lethal,body color defective" mesothoracic tergum FBgn0060394 l(3)S132802b lethal (3) S132802b http://flybase.net/reports/FBgn0060394.html gene 1328/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0034443 cer crammer http://flybase.net/reports/FBgn0034443.html protein_coding_gene "0008234=cysteine-type peptidase activity, 0004869=cysteine-type endopeptidase inhibitor activity" "0007616=long-term memory, 0097340=inhibition of cysteine-type endopeptidase activity, 0007614=short-term memory" "0012505=endomembrane system, 0005764=lysosome" "D/CTLA-2, CG10460, CER, Drosophila CTLA-2like protein" "IPR013128=Peptidase C1A, IPR013201=Cathepsin propeptide inhibitor domain (I29)" CG10460 16-Dec-15 2015_12 "ENSMUSG00000074874,ENSMUSG00000044258(Ctla2a)" "memory defective,recessive,feeding behavior defective,viable" FBgn0032280 CG17105 http://flybase.net/reports/FBgn0032280.html protein_coding_gene CG17105 16-Dec-15 2015_12 viable FBgn0062654 EP3621 EP3621 http://flybase.net/reports/FBgn0062654.html gene EP(3)3621 16-Dec-15 2015_12 FBgn0040674 CG9445 http://flybase.net/reports/FBgn0040674.html protein_coding_gene 0007498=mesoderm development CG9445 16-Dec-15 2015_12 viable FBgn0065151 l(3)SH066 lethal (3) SH066 http://flybase.net/reports/FBgn0065151.html gene l(2)SH3 066 16-Dec-15 2015_12 "lethal,recessive" FBgn0263129 Cbl::drk Cbl::drk http://flybase.net/reports/FBgn0263129.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0034352 CG17669 http://flybase.net/reports/FBgn0034352.html protein_coding_gene "IPR028235=Dynein assembly factor 3, C-terminal domain, IPR027974=Domain of unknown function DUF4470" CG17669 16-Dec-15 2015_12 "ENSDARG00000071423,ENSDARG00000036304(LOC100148431)" ENSXETG00000024675(C19orf51) ENSMUSG00000055809(6030429G01Rik) ENSG00000167646(C19orf51) viable FBgn0085690 CG41559 http://flybase.net/reports/FBgn0085690.html FBan0041559 protein_coding_gene 16-Dec-15 2015_12 FBgn0067856 Theseus Theseus http://flybase.net/reports/FBgn0067856.html gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0008354=germ cell migration" 0016021=integral component of membrane theseus 16-Dec-15 2015_12 FBgn0259969 Sfp65A Seminal fluid protein 65A http://flybase.net/reports/FBgn0259969.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 65A, CG42479" CG42479 16-Dec-15 2015_12 FBgn0086383 BG01533 http://flybase.net/reports/FBgn0086383.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0053109 CG33109 http://flybase.net/reports/FBgn0053109.html FBgn0038212 protein_coding_gene "cg9645, CG9645" CG33109 16-Dec-15 2015_12 FBgn0022095 l(2)k07219 lethal (2) k07219 http://flybase.net/reports/FBgn0022095.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037330 mRpL44 mitochondrial ribosomal protein L44 http://flybase.net/reports/FBgn0037330.html protein_coding_gene "0004525=ribonuclease III activity, 0003723=RNA binding, 0003735=structural constituent of ribosome" "0022008=neurogenesis, 0006396=RNA processing, 0032543=mitochondrial translation" 0005762=mitochondrial large ribosomal subunit "MRP-L44, CG2109" IPR000999=Ribonuclease III domain CG2109 16-Dec-15 2015_12 ENSDARG00000010094(mrpl44) YMR024W(MRPL3) ENSXETG00000014771(mrpl44) ENSMUSG00000026248(Mrpl44) ENSG00000135900(MRPL44) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0033971 CG10209 http://flybase.net/reports/FBgn0033971.html protein_coding_gene 0003677=DNA binding 0006915=apoptotic process 0005634=nucleus "IPR004210=BESS motif, IPR028002=Myb/SANT-like DNA-binding domain, IPR026753=Nuclear apoptosis-inducing factor 1" CG10209 16-Dec-15 2015_12 lethal FBgn0264265 CR43765 http://flybase.net/reports/FBgn0264265.html non_protein_coding_gene lincRNA.231 CR43765 16-Dec-15 2015_12 FBgn0017577 Mcm5 Minichromosome maintenance 5 http://flybase.net/reports/FBgn0017577.html protein_coding_gene "0005524=ATP binding, 0003682=chromatin binding, 0003688=DNA replication origin binding, 0043138=3'-5' DNA helicase activity" "0006270=DNA replication initiation, 0007126=meiotic nuclear division, 0030261=chromosome condensation, 0000712=resolution of meiotic recombination intermediates, 0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0042023=DNA endoreduplication" "0042555=MCM complex, 0005656=nuclear pre-replicative complex" "mcm5, PCR4, DmCDC465, DmCDC46, DmMCM5, MCM5, CG4082, mini-chromosome maintenance 5, minichromosome maintenance 5, DmeMCM5, DmMcm5, McM5" "IPR008048=DNA replication licensing factor Mcm, IPR003593=AAA+ ATPase domain, IPR001208=MCM domain, IPR012340=Nucleic acid-binding, OB-fold, IPR027925=MCM N-terminal domain, IPR031327=Mini-chromosome maintenance protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR018525=Mini-chromosome maintenance, conserved site" CG4082 16-Dec-15 2015_12 ENSDARG00000019507(mcm5) YLR274W(MCM5) WBGene00003157(mcm-5) ENSXETG00000000253(mcm5) ENSMUSG00000005410(Mcm5) ENSG00000100297(MCM5) "viable,meiotic cell cycle defective,fertile,lethal,recessive,visible" "nuclear chromosome,imaginal disc,trichogen cell" FBgn0267694 CR46030 http://flybase.net/reports/FBgn0267694.html non_protein_coding_gene CR46030 16-Dec-15 2015_12 FBgn0034356 CG10924 http://flybase.net/reports/FBgn0034356.html protein_coding_gene "0004613=phosphoenolpyruvate carboxykinase (GTP) activity, 0005525=GTP binding" 0006094=gluconeogenesis 0005739=mitochondrion "predicted phosphoenolpyruvate carboxykinase, Pepck isogene, PEPCK" "IPR008210=Phosphoenolpyruvate carboxykinase, N-terminal, IPR008209=Phosphoenolpyruvate carboxykinase, GTP-utilising, IPR013035=Phosphoenolpyruvate carboxykinase, C-terminal, IPR018091=Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site" CG10924 16-Dec-15 2015_12 "ENSDARG00000013522(pck1),ENSDARG00000020956(pck2)" "WBGene00011232(R11A5.4),WBGene00021043(W05G11.6)" "ENSXETG00000014608(pck2),ENSXETG00000011266(pck1)" "ENSMUSG00000040618(Pck2),ENSMUSG00000027513(Pck1)" "ENSG00000100889(PCK2),ENSG00000124253(PCK1)" "viable,fertile" FBgn0002176 l(3)7E103 lethal (3) 7E103 http://flybase.net/reports/FBgn0002176.html gene 16-Dec-15 2015_12 lethal FBgn0265401 EP902 http://flybase.net/reports/FBgn0265401.html gene 16-Dec-15 2015_12 FBgn0011622 l(2)10610 lethal (2) 10610 http://flybase.net/reports/FBgn0011622.html gene 16-Dec-15 2015_12 lethal FBgn0053246 Ste:CG33246 Ste:CG33246 http://flybase.net/reports/FBgn0053246.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG33246, CG32605" "IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG33246 16-Dec-15 2015_12 FBgn0014877 Roe1 Roe1 http://flybase.net/reports/FBgn0014877.html FBgn0064950 protein_coding_gene "0000774=adenyl-nucleotide exchange factor activity, 0042803=protein homodimerization activity, 0051087=chaperone binding, 0051082=unfolded protein binding" "0006457=protein folding, 0006626=protein targeting to mitochondrion, 0022008=neurogenesis" "0005739=mitochondrion, 0005759=mitochondrial matrix" "CG6155, droe1, BcDNA:GM03203, cg6155, DROE1, Droe1" "IPR013805=GrpE nucleotide exchange factor, coiled-coil, IPR000740=GrpE nucleotide exchange factor, IPR009012=GrpE nucleotide exchange factor, head" CG6155 16-Dec-15 2015_12 ENSDARG00000010021(grpel1) YOR232W(MGE1) WBGene00007927(C34C12.8) ENSXETG00000022900(grpel1) ENSMUSG00000029198(Grpel1) ENSG00000109519(GRPEL1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0061012 l(3)S026111 lethal (3) S026111 http://flybase.net/reports/FBgn0061012.html gene 0261/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0005176 l(2)Stn lethal of Steinmetz http://flybase.net/reports/FBgn0005176.html gene lethal (2) of Steinmetz 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "eye,cuticle" FBgn0010190 tu-54e tu-54e http://flybase.net/reports/FBgn0010190.html gene 16-Dec-15 2015_12 melanotic mass phenotype FBgn0037646 CAHë_ Carbonic anhydrase ë_ http://flybase.net/reports/FBgn0037646.html protein_coding_gene "0008270=zinc ion binding, 0004089=carbonate dehydratase activity" 0006730=one-carbon metabolic process 0005739=mitochondrion "Dmel_CG11967, CG11967, GH10821P, beta-carbonic anhydrase, DmBCA, beta-CA, CAHbeta" IPR001765=Carbonic anhydrase CG11967 16-Dec-15 2015_12 "WBGene00013805(bca-2),WBGene00000245(bca-1)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051784 CG31784 http://flybase.net/reports/FBgn0051784.html FBgn0045405 protein_coding_gene NEST:bs05c10 "IPR026295=Coiled-coil domain-containing protein 81, IPR025254=Domain of unknown function DUF4201" CG31784 16-Dec-15 2015_12 "viable,fertile,visible" mesothoracic tergum FBgn0069178 mcl(2)Z3384 mcl(2)Z3384 http://flybase.net/reports/FBgn0069178.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0036414 nan nanchung http://flybase.net/reports/FBgn0036414.html protein_coding_gene "0005262=calcium channel activity, 0005261=cation channel activity" "0007605=sensory perception of sound, 0010996=response to auditory stimulus, 0048060=negative gravitaxis, 0006812=cation transport, 0006816=calcium ion transport, 0009270=response to humidity, 0055085=transmembrane transport, 0050974=detection of mechanical stimulus involved in sensory perception, 0001964=startle response" 0034703=cation channel complex "Nan, CG5842, Nanchung, DmNan, NAN, NANCHUNG, TRPV, transient receptor potential vanilloid, CT18317, OCR" "IPR005821=Ion transport domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG5842 16-Dec-15 2015_12 "ENSDARG00000014496(trpv6),ENSDARG00000061941(trpv4)" WBGene00003841(ocr-4) "ENSXETG00000022857(),ENSXETG00000005790(TRPV1),ENSXETG00000005811(TRPV2),ENSXETG00000018609(),ENSXETG00000003136(),ENSXETG00000005788(TRPV3),ENSXETG00000003140(),ENSXETG00000013395(),ENSXETG00000011201()" "ENSMUSG00000036899(Trpv5),ENSMUSG00000029868(Trpv6)" "ENSG00000127412(TRPV5),ENSG00000165125(TRPV6)" "courtship behavior defective,recessive,viable,uncoordinated,auditory perception defective,neurophysiology defective,behavior defective,locomotor behavior defective,gravitaxis defective,lethal" Johnston organ neuron FBgn0029058 l(1)G0435 lethal (1) G0435 http://flybase.net/reports/FBgn0029058.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263467 snoRNA:nop5-x16-a http://flybase.net/reports/FBgn0263467.html snoRNA_gene "snoCD_05, snoRNA:nop_x16-a" CR43582 16-Dec-15 2015_12 FBgn0082926 snoRNA:Me28S-U1848 snoRNA:Me28S-U1848 http://flybase.net/reports/FBgn0082926.html snoRNA_gene "Me28s-U1848, Me28S-Um1848, CR34535" CR34535 16-Dec-15 2015_12 FBgn0001422 l(1)6Df lethal (1) 6Df http://flybase.net/reports/FBgn0001422.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0267557 CR45897 http://flybase.net/reports/FBgn0267557.html non_protein_coding_gene CR45897 16-Dec-15 2015_12 FBgn0025628 CG4199 http://flybase.net/reports/FBgn0025628.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0051537=2 iron, 2 sulfur cluster binding, 0016491=oxidoreductase activity" "0045454=cell redox homeostasis, 0055114=oxidation-reduction process" "143005_at, EG:22E5.5" "IPR017941=Rieske [2Fe-2S] iron-sulphur domain, IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR004099=Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR016156=FAD/NAD-linked reductase, dimerisation domain" CG4199 16-Dec-15 2015_12 ENSDARG00000062780(LOC100150876) WBGene00017640(F20D6.11) ENSXETG00000008277(AIFM3) ENSMUSG00000022763(Aifm3) ENSG00000183773(AIFM3) "viable,fertile" FBgn0003991 vss variable size and shape http://flybase.net/reports/FBgn0003991.html gene 0048477=oogenesis vss-1 16-Dec-15 2015_12 "female sterile,maternal effect" egg FBgn0067734 l(1)G0463 lethal (1) G0463 http://flybase.net/reports/FBgn0067734.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0262068 EG56 http://flybase.net/reports/FBgn0262068.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266829 CR45291 http://flybase.net/reports/FBgn0266829.html non_protein_coding_gene CR45291 16-Dec-15 2015_12 FBgn0082942 snoRNA:Me28S-A982b snoRNA:Me28S-A982b http://flybase.net/reports/FBgn0082942.html snoRNA_gene "Me28S-Am982b, CR34528, DmSnR39/59b" CR34528 16-Dec-15 2015_12 FBgn0030066 CG1885 http://flybase.net/reports/FBgn0030066.html protein_coding_gene 0004852=uroporphyrinogen-III synthase activity 0033014=tetrapyrrole biosynthetic process "IPR003754=Tetrapyrrole biosynthesis, uroporphyrinogen III synthase" CG1885 16-Dec-15 2015_12 ENSDARG00000027491(uros) YOR278W(HEM4) ENSXETG00000025196(UROS) ENSMUSG00000030979(Uros) ENSG00000188690(UROS) FBgn0035829 HP4 Heterochromatin protein 4 http://flybase.net/reports/FBgn0035829.html FBgn0062494 protein_coding_gene 0006325=chromatin organization "0005700=polytene chromosome, 0005704=polytene chromosome band, 0005720=nuclear heterochromatin, 0005701=polytene chromosome chromocenter, 0005730=nucleolus, 0035012=polytene chromosome, telomeric region, 0010369=chromocenter" "hip, BcDNA:GM01628, Heterochromatin Protein 4, CG8044, Hip, HP1-interacting protein" CG8044 16-Dec-15 2015_12 "viable,fertile,suppressor of variegation,dominant" FBgn0051279 CG31279 http://flybase.net/reports/FBgn0051279.html protein_coding_gene CG31279 16-Dec-15 2015_12 FBgn0031053 CG14223 http://flybase.net/reports/FBgn0031053.html protein_coding_gene IPR029201=Jiraiya CG14223 16-Dec-15 2015_12 DRSC24816 K -0.111555407 -0.194712974 0.089880742 -0.097187759 1.630112523 0.81189103 FBgn0283478 und uninitiated http://flybase.net/reports/FBgn0283478.html "FBgn0025117, FBgn0015525" protein_coding_gene "0004177=aminopeptidase activity, 0008235=metalloexopeptidase activity" 0006508=proteolysis "DMAP2, unnamed, p67, MAP2, CG4008" "IPR000994=Peptidase M24, structural domain, IPR002468=Peptidase M24A, methionine aminopeptidase, subfamily 2, IPR001714=Peptidase M24, methionine aminopeptidase, IPR011991=Winged helix-turn-helix DNA-binding domain" CG4008 16-Dec-15 2015_12 "ENSDARG00000028657(metap2),ENSDARG00000069261(metap2l)" YBL091C(MAP2) WBGene00003130(map-2) ENSXETG00000009238(metap2) ENSMUSG00000036112(Metap2) ENSG00000111142(METAP2) "partially lethal - majority die,recessive,visible,planar polarity defective,wild-type,viable" "eye,wing,anterior,ommatidium,eye photoreceptor cell,ventral,wing vein L5,trichogen cell" FBgn0000117 arm armadillo http://flybase.net/reports/FBgn0000117.html "FBgn0029069, FBgn0040191, FBgn0045040" protein_coding_gene "0005515=protein binding, 0019900=kinase binding, 0005198=structural molecule activity, 0045294=alpha-catenin binding, 0008134=transcription factor binding, 0008092=cytoskeletal protein binding, 0045296=cadherin binding, 0019901=protein kinase binding, 0004871=signal transducer activity, 0003713=transcription coactivator activity, 0001105=RNA polymerase II transcription coactivator activity, 0032403=protein complex binding" "0035153=epithelial cell type specification, open tracheal system, 0000902=cell morphogenesis, 0007163=establishment or maintenance of cell polarity, 0014017=neuroblast fate commitment, 0007155=cell adhesion, 0045186=zonula adherens assembly, 0016055=Wnt signaling pathway, 0072659=protein localization to plasma membrane, 0035293=chitin-based larval cuticle pattern formation, 0060914=heart formation, 0035147=branch fusion, open tracheal system, 0007507=heart development, 0046530=photoreceptor cell differentiation, 0014019=neuroblast development, 0007293=germarium-derived egg chamber formation, 0007370=ventral furrow formation, 0060429=epithelium development, 0048526=imaginal disc-derived wing expansion, 0007472=wing disc morphogenesis, 0007016=cytoskeletal anchoring at plasma membrane, 0060232=delamination, 0007616=long-term memory, 0007399=nervous system development, 0071896=protein localization to adherens junction, 0030707=ovarian follicle cell development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0035017=cuticle pattern formation, 0048599=oocyte development, 0001745=compound eye morphogenesis, 0007391=dorsal closure, 0048754=branching morphogenesis of an epithelial tube, 0045893=positive regulation of transcription, DNA-templated, 0007400=neuroblast fate determination, 0048477=oogenesis, 0003136=negative regulation of heart induction by canonical Wnt signaling pathway, 0035019=somatic stem cell maintenance, 0046667=compound eye retinal cell programmed cell death, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0001709=cell fate determination, 0008360=regulation of cell shape, 0016337=single organismal cell-cell adhesion" "0009898=cytoplasmic side of plasma membrane, 0030018=Z disc, 0016020=membrane, 0005886=plasma membrane, 0016342=catenin complex, 0030424=axon, 0016323=basolateral plasma membrane, 0005667=transcription factor complex, 0030139=endocytic vesicle, 0005916=fascia adherens, 0005634=nucleus, 0016324=apical plasma membrane, 0005912=adherens junction, 0005737=cytoplasm, 0005829=cytosol, 0005915=zonula adherens, 0005914=spot adherens junction, 0016327=apicolateral plasma membrane, 0030057=desmosome, 0030877=beta-catenin destruction complex" "catenin, l(1)2Bv, beta-Cat, Dm Arm, CG11579, EG:86E4.6, beta-catenin/Armadillo, beta-cat-arm, t12687 ALR Dm, beta-catenin/Arm, Beta-catenin, bgr;-catenin, Beta-catenin/Arm, l(1)G0192, l(1)G0410, beta-Catenin, bgr;-Cat, Armadillo/bgr;-catenin, betacat, ARM, Arm, beta-cat, Armadillo, l(1)arm, Armadillo(Arm)/beta-catenin, alpha-Catenin, l(1)G0234, Armadillo/beta-catenin, b-catenin, betacatenin, ARMADILLO, beta-catenin" "IPR013284=Beta-catenin, IPR000225=Armadillo, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG11579 16-Dec-15 2015_12 ENSDARG00000014571(ctnnb1) WBGene00001979(hmp-2) ENSXETG00000013848(ctnnb1) ENSMUSG00000006932(Ctnnb1) ENSG00000168036(CTNNB1) " larval stage , embryonic stage , oogenesis stage && adult stage | female , embryonic stage | stage >12 , embryonic stage | stage 13-14 , embryonic stage | stage 9 , embryonic stage | stage 13-16 , embryonic stage | late , embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 17 , embryonic stage | embryonic cycle 14 , embryonic stage | late && larval stage , adult stage " " embryonic/larval salivary gland

, embryonic central nervous system

, follicle cell

, tracheal system

, peripheral nervous system

, gonad | restricted

, eye-antennal disc

, ventral midline

, proctodeum

, sense organ

, midline glial cell

, embryonic/larval foregut

, imaginal disc

, optic lobe

, labral segment

, larval anus

, ventral nerve cord

, gonad | restricted & anterior

, motor neuron &&of intersegmental nerve

, stomodeum

, mesoderm

, embryonic/larval hindgut

, antennal segment

, supraesophageal ganglion

, Malpighian tubule

, tracheal pit

, oocyte

, longitudinal connective

, neuron

, proventriculus

, embryonic/larval digestive system

, ventral nerve cord commissure

, larval brain

, embryonic/larval posterior spiracle

, embryonic peripheral nervous system

, motor neuron &&of segmental nerve

, larval muscle system

, nurse cell

, posterior embryonic/larval midgut

, head

" "viable,fertile,visible,partially lethal - majority die,lethal,lethal - all die before end of embryonic stage,segment polarity phenotype,heat sensitive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,recessive,male,female,germline clone,planar polarity defective,cell non-autonomous,somatic clone,cell autonomous,cell polarity defective,cell migration defective,cell shape defective,wild-type,increased cell death,size defective,mitotic cell cycle defective,neuroanatomy defective,memory defective,RU486 conditional,hyperplasia" "wing margin,wing,alula,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,abdominal sternite 6,dorsal row,ventral row,tarsal segment,interommatidial bristle,ectopic,somatic clone,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,embryonic head,dorsal closure embryo,embryo,segment,tracheal branch primordium,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,RP2 motor neuron,presumptive embryonic/larval central nervous system,longitudinal connective,commissure,embryonic epidermis,embryonic/first instar larval cuticle,follicle stem cell,embryonic/larval tracheal system,abdominal ventral denticle belt,denticle,dorsal,follicle cell,imaginal disc,gonad,oocyte,ovariole,germline clone,egg,nurse cell & nucleus | germ-line clone,egg chamber,nurse cell,nurse cell ring canal,ventral,ovary,embryonic gnathal segment,embryonic segment,cell autonomous,cardial valve,precursor,embryonic dorsal epidermis,embryonic ventral epidermis,embryonic optic lobe primordium,midgut constriction 2,tracheal metamere,embryonic/larval ganglionic branch,embryonic/larval dorsal branch,embryonic/larval dorsal vessel,denticle belt,stomodeal invagination,pleurum,adult cuticle & abdomen | somatic clone,ommatidium,eye,embryonic Malpighian tubule,maternal effect,contractile ring | somatic clone,midbody | somatic clone,female germline stem cell,germline cell,epithelial cell,cytoskeleton | somatic clone,embryonic/larval dorsal branch 10,spiracular branch 10,MP1 neuron,pCC neuron,dMP2 neuron,vMP2 neuron,embryonic ventral nervous system,nurse cell & nucleus,cytoskeleton,actin filament,nurse cell & actin filament,oocyte & actin filament,border follicle cell,dorsal trunk primordium,posterior spiracle primordium,embryonic leading edge cell,syncytial blastoderm embryo,nucleus | embryonic stage 4 | germline clone,spot adherens junction,actin cytoskeleton | embryonic stage | maternal effect,zonula adherens,embryonic/larval cuticle,adherens junction,ventral furrow,embryonic neuroblast,eye photoreceptor cell,spindle | cleavage stage | maternal effect,cell non-autonomous,pigment cell,dorsal margin photoreceptor,retina,heart primordium,adherens junction | germline clone,salivary gland,dorsal mesothoracic disc & peripodial epithelium | somatic clone | cell autonomousë±Tub84B.PL,wing hinge primordium,embryonic/first instar larval cuticle & denticleda.G32,wing margin bristle,wing vein,wing sensillum,crossvein,wing disc,lymph gland derived hemocyte | third instar larval stage,macrochaeta,embryonic/first instar larval cuticle & denticle | ectopicda.G32,morphogenetic furrow,antennal disc,T1 beard,wing hinge,anterior compartment,sensory mother cell & dorsal mesothoracic disc | ectopicsd-SG29.1,embryonic/first instar larval cuticle & denticle beltda.G32,embryonic/larval visceral branch,tracheal fusion cell,supernumerary,terminal tracheal cell,direct flight muscle,denticle row 1,interfollicle cell,heat sensitive,midgut constriction 1,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,dorsal hair,dorsal denticle,dorsal thick hair,dorsal fine hair,pleural membrane,abdominal sternite bristle,sternite,wing hair,testis,dorsal cluster neuron | adult stage,medulla | adult stage,eye disc,posterior,extended germ band embryo,mesothoracic tergum,adult heart,male genitalia,epithelium,female germline cyst,photoreceptor cell,genital disc,nucleus,embryonic/larval salivary gland,wing & macrochaetaC-765,wing & macrochaeta | ectopicC-765" FBgn0015925 csul capsuleen http://flybase.net/reports/FBgn0015925.html FBgn0028723 protein_coding_gene "0016274=protein-arginine N-methyltransferase activity, 0008276=protein methyltransferase activity" "0035246=peptidyl-arginine N-methylation, 0018216=peptidyl-arginine methylation, 0030719=P granule organization, 0007315=pole plasm assembly, 0008298=intracellular mRNA localization, 0007067=mitotic nuclear division, 0007318=pole plasm protein localization" 0005737=cytoplasm "Drosophila arginine methyltransferase 5, PRMT5, Dart5, Capsuleen, dprmt5, Csul, dPRMT5, JBP1, dart5, capsuleenn, DART5, CG3730" "IPR025799=Protein arginine N-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR007857=Protein arginine N-methyltransferase PRMT5" CG3730 16-Dec-15 2015_12 ENSDARG00000054357(LOC100331851) YBR133C(HSL7) WBGene00016408(prmt-5) ENSXETG00000022626(PRMT5) ENSMUSG00000023110(Prmt5) ENSG00000100462(PRMT5) "viable,male sterile,grandchildless,fertile,female sterile,recessive" "pole cell,testis,spermatozoon,spermatid,spermatid cyst,embryonic abdominal segment,maternal effect" FBgn0263766 CR43683 http://flybase.net/reports/FBgn0263766.html non_protein_coding_gene CR43683 16-Dec-15 2015_12 FBgn0040828 CG13306 http://flybase.net/reports/FBgn0040828.html protein_coding_gene CG13306 16-Dec-15 2015_12 viable FBgn0038300 CG4203 http://flybase.net/reports/FBgn0038300.html protein_coding_gene 0005515=protein binding "0007411=axon guidance, 0034088=maintenance of mitotic sister chromatid cohesion" "0005634=nucleus, 0032116=SMC loading complex, 0000785=chromatin, 0005654=nucleoplasm" "FBgn0038300, Mau-2, MAU-2" "IPR011990=Tetratricopeptide-like helical domain, IPR019440=Cohesin loading factor" CG4203 16-Dec-15 2015_12 ENSDARG00000042056 WBGene00003136(mau-2) ENSXETG00000013046(KIAA0892) ENSMUSG00000031858(9130404D08Rik) ENSG00000129933(MAU2) FBgn0069183 mcl(2)Z0218 mcl(2)Z0218 http://flybase.net/reports/FBgn0069183.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0016820 l(1)L7 lethal (1) L7 http://flybase.net/reports/FBgn0016820.html gene L7 16-Dec-15 2015_12 "lethal,recessive" FBgn0266635 CR45142 http://flybase.net/reports/FBgn0266635.html non_protein_coding_gene CR45142 16-Dec-15 2015_12 FBgn0011190 l(1)296-15 lethal (1) 296-15 http://flybase.net/reports/FBgn0011190.html FBgn0010201 gene 296-15 16-Dec-15 2015_12 "lethal,recessive" FBgn0065925 l(2)SH0147 lethal (2) SH0147 http://flybase.net/reports/FBgn0065925.html gene l(2)SH2 0147 16-Dec-15 2015_12 "lethal,recessive" FBgn0036305 CG10984 http://flybase.net/reports/FBgn0036305.html protein_coding_gene 0005654=nucleoplasm CG10984 16-Dec-15 2015_12 "ENSXETG00000011277(),ENSXETG00000004049()" "ENSMUSG00000034647(Ankrd12),ENSMUSG00000035569(Ankrd11)" "ENSG00000101745(ANKRD12),ENSG00000167522(ANKRD11)" "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC09817 I -0.837062389 1.53646434 -0.521230289 0.725690648 0.257855167 0.649275555 FBgn0028579 phtf phtf http://flybase.net/reports/FBgn0028579.html FBgn0028488 protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" 0006357=regulation of transcription from RNA polymerase II promoter 0005634=nucleus "CG3268, BcDNA:GH08636, BcDNA.GH08636, putative homeodomain transcription factor, d-phtf" "IPR021980=Transcription factor homeodomain, male germ-cell" CG3268 16-Dec-15 2015_12 ENSDARG00000057708(zgc:175264) ENSXETG00000019722(PHTF2) "ENSMUSG00000039987(Phtf2),ENSMUSG00000058388(Phtf1)" "ENSG00000006576(PHTF2),ENSG00000116793(PHTF1)" adult stage male germline stem cell

viable FBgn0003950 unc uncoordinated http://flybase.net/reports/FBgn0003950.html FBgn0031160 protein_coding_gene "0007605=sensory perception of sound, 0007626=locomotory behavior, 0007283=spermatogenesis, 0035058=nonmotile primary cilium assembly" "0035869=ciliary transition zone, 0036064=ciliary basal body, 0005814=centriole" "section 3, CG1501, 5, section 5, Uncoordinated, l(1)19Ef, 3, 4, section 4, Unc, UNC, lLV7, W5, l(1)6-3-212" CG1501 16-Dec-15 2015_12 "viable,fertile,touch sensitivity defective,recessive,behavior defective,somatic clone,lethal,auditory perception defective,uncoordinated,neurophysiology defective,locomotor behavior defective,touch perception defective" "elongation stage spermatid,spermatid axoneme,elongation stage spermatid & nucleus,olfactory neuron & cilium,scolopidial cilium,spermatocyte & centriole,wing,leg,macrochaeta,adult antennal nerve" FBgn0058457 5.8SrRNA:CR40457 5.8SrRNA:CR40457 http://flybase.net/reports/FBgn0058457.html rRNA_gene CR40457 16-Dec-15 2015_12 FBgn0265822 CR44611 http://flybase.net/reports/FBgn0265822.html non_protein_coding_gene CR44611 16-Dec-15 2015_12 FBgn0083264 E(smoDN)529 Enhancer of smoDN 529 http://flybase.net/reports/FBgn0083264.html gene 16-Dec-15 2015_12 FBgn0043380 EP787 EP787 http://flybase.net/reports/FBgn0043380.html gene "EP0787, EP(2)0787" 16-Dec-15 2015_12 visible "scutellar bristle,tormogen cell" FBgn0036211 CG5946 http://flybase.net/reports/FBgn0036211.html protein_coding_gene "0004128=cytochrome-b5 reductase activity, acting on NAD(P)H" "0002121=inter-male aggressive behavior, 0055114=oxidation-reduction process" 0012505=endomembrane system "IPR001433=Oxidoreductase FAD/NAD(P)-binding, IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR008333=Oxidoreductase, FAD-binding domain, IPR001834=NADH:cytochrome b5 reductase (CBR), IPR017938=Riboflavin synthase-like beta-barrel, IPR001709=Flavoprotein pyridine nucleotide cytochrome reductase" CG5946 16-Dec-15 2015_12 "ENSDARG00000018966(dia1),ENSDARG00000005891(cyb5r3)" "YIL043C(CBR1),YML125C(PGA3)" "WBGene00020268(T05H4.5),WBGene00020267(T05H4.4)" "ENSXETG00000016513(CYB5R3),ENSXETG00000009054(TNeu132f07.1)" ENSMUSG00000026456(Cyb5r1) "ENSG00000100243(CYB5R3),ENSG00000159348(CYB5R1)" "behavior defective,recessive,viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0032172 CG5850 http://flybase.net/reports/FBgn0032172.html protein_coding_gene IPR005178=Organic solute transporter subunit alpha/Transmembrane protein 184 CG5850 16-Dec-15 2015_12 YKR051W() ENSXETG00000007110(TNeu134j15.1) ENSMUSG00000031617(Tmem184c) ENSG00000164168(TMEM184C) "viable,fertile" FBgn0032729 CG10639 http://flybase.net/reports/FBgn0032729.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process 0005811=lipid particle IPR006076=FAD dependent oxidoreductase CG10639 16-Dec-15 2015_12 ENSDARG00000060500(l2hgdh) WBGene00021564(Y45G12B.3) ENSXETG00000019714(L2HGDH) ENSMUSG00000020988(L2hgdh) ENSG00000087299(L2HGDH) "viable,fertile" FBgn0265443 CR44343 http://flybase.net/reports/FBgn0265443.html non_protein_coding_gene lincRNA.301 CR44343 16-Dec-15 2015_12 FBgn0020794 oo oculus obscurus http://flybase.net/reports/FBgn0020794.html gene 16-Dec-15 2015_12 FBgn0086655 jing jing http://flybase.net/reports/FBgn0086655.html "FBgn0041145, FBan0009403, FBgn0010347, FBgn0010475, FBgn0026656, FBgn0033077" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007417=central nervous system development, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007479=leg disc proximal/distal pattern formation, 0007411=axon guidance, 0007476=imaginal disc-derived wing morphogenesis, 0007298=border follicle cell migration, 0007418=ventral midline development, 0007474=imaginal disc-derived wing vein specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042246=tissue regeneration, 0007382=specification of segmental identity, maxillary segment, 0008347=glial cell migration, 0007424=open tracheal system development" "0005634=nucleus, 0035098=ESC/E(Z) complex" "1.28, l(2)22F3, deformed, rhumba, l(2)01094, CG9397, CG9403, CT9093, Jing, AEBP2" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG9397 16-Dec-15 2015_12 " embryonic stage | stage 10-16 , embryonic stage , embryonic stage | stage 9-15 , embryonic stage | stage 9 " " tracheal primordium

anterior , embryonic abdominal segment 8 | restricted

, proctodeum

, ventral midline

, ventral neurogenic region | segmentally repeated

, epidermis &&of embryonic maxillary segment

, embryonic/larval hindgut

, embryonic prothoracic segment | restricted

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, supraesophageal ganglion

" " embryonic stage | stage 9-14 , embryonic stage | stage 10-16 " " ventral midline

, tracheal primordium

" FBgn0085497 CG40577 http://flybase.net/reports/FBgn0085497.html FBan0040577 protein_coding_gene 16-Dec-15 2015_12 FBgn0260657 CG42540 http://flybase.net/reports/FBgn0260657.html "FBgn0035559, FBgn0035560, FBgn0040700, FBgn0052245" protein_coding_gene 0016020=membrane "CG13719, CG7468, CG32245, CG13718" "IPR018080=Band 7/stomatin-like, conserved site, IPR001107=Band 7 protein, IPR001972=Stomatin family" CG42540 16-Dec-15 2015_12 ENSDARG00000003835(stom) "WBGene00003166(mec-2),WBGene00006066(sto-4)" ENSXETG00000016014(stoml3) ENSMUSG00000026880(Stom) "ENSG00000148175(STOM),ENSG00000133115(STOML3)" DRSC23011 K -0.571316278 2.483099691 FBgn0038584 mTerf5 http://flybase.net/reports/FBgn0038584.html protein_coding_gene 0003690=double-stranded DNA binding "0006355=regulation of transcription, DNA-templated, 0006390=transcription from mitochondrial promoter" 0005739=mitochondrion "CG7175, D-MTERF5" IPR003690=Mitochodrial transcription termination factor CG7175 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0031720 CG14013 http://flybase.net/reports/FBgn0031720.html protein_coding_gene IPR027887=Protein of unknown function DUF4464 CG14013 16-Dec-15 2015_12 ENSXETG00000021537(C4orf22) ENSMUSG00000057816(1700007G11Rik) ENSG00000197826(C4orf22) "viable,body color defective" mesothoracic tergum FBgn0039655 CG14507 http://flybase.net/reports/FBgn0039655.html protein_coding_gene "0004623=phospholipase A2 activity, 0005509=calcium ion binding" "0006644=phospholipid metabolic process, 0016042=lipid catabolic process" "IPR001211=Phospholipase A2, IPR016090=Phospholipase A2 domain, IPR013090=Phospholipase A2, active site" CG14507 16-Dec-15 2015_12 "viable,fertile" FBgn0033917 CG8503 http://flybase.net/reports/FBgn0033917.html protein_coding_gene "0008270=zinc ion binding, 0042826=histone deacetylase binding" 0010629=negative regulation of gene expression 0005737=cytoplasm "IPR002893=Zinc finger, MYND-type, IPR001214=SET domain" CG8503 16-Dec-15 2015_12 viable FBgn0266320 CR44985 http://flybase.net/reports/FBgn0266320.html non_protein_coding_gene CR44985 16-Dec-15 2015_12 FBgn0065216 l(2)SH2245 lethal (2) SH2245 http://flybase.net/reports/FBgn0065216.html gene l(2)SH2 2245 16-Dec-15 2015_12 "lethal,recessive" FBgn0039820 CG15554 http://flybase.net/reports/FBgn0039820.html FBgn0047169 protein_coding_gene BcDNA:RE10288 CG15554 16-Dec-15 2015_12 viable FBgn0067635 188y 188y http://flybase.net/reports/FBgn0067635.html gene 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0031817 CG9531 http://flybase.net/reports/FBgn0031817.html protein_coding_gene "0004729=oxygen-dependent protoporphyrinogen oxidase activity, 0003676=nucleic acid binding, 0008276=protein methyltransferase activity" 0006479=protein methylation "IPR002052=DNA methylase, N-6 adenine-specific, conserved site, IPR004556=Modification methylase HemK, IPR007848=Methyltransferase small domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG9531 16-Dec-15 2015_12 ENSXETG00000000079(HEMK1) ENSMUSG00000032579(Hemk1) ENSG00000114735(HEMK1) DRSC03253 I -0.532977549 -1.501088159 0.798429161 -0.688992968 -0.755058209 -0.305129477 FBgn0027984 l(3)S133501b lethal (3) S133501b http://flybase.net/reports/FBgn0027984.html gene "1335/01, l(3)S133501" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026654 l(2)2D8 lethal (2) 2D8 http://flybase.net/reports/FBgn0026654.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0021970 l(2)k10004 lethal (2) k10004 http://flybase.net/reports/FBgn0021970.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051501 nxf4 nuclear export factor 4 http://flybase.net/reports/FBgn0051501.html "FBgn0037499, FBgn0063751" protein_coding_gene 0006405=RNA export from nucleus "CG14604, BcDNA:AT07692, CG31501" "IPR001611=Leucine-rich repeat, IPR030217=Nuclear RNA export factor" CG31501 16-Dec-15 2015_12 viable DRSC12548 K 1.179127539 -0.356736203 0.547612129 -0.433458046 -1.572906876 -0.452319842 FBgn0053395 5SrRNA:CR33395 5SrRNA:CR33395 http://flybase.net/reports/FBgn0053395.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33395 CR33395 16-Dec-15 2015_12 FBgn0270928 VAChT Vesicular acetylcholine transporter http://flybase.net/reports/FBgn0270928.html "FBgn0015323, FBgn0052848, FBgn0064131, FBgn0015023" protein_coding_gene "0015238=drug transmembrane transporter activity, 0005278=acetylcholine:proton antiporter activity, 0005277=acetylcholine transmembrane transporter activity" "0055085=transmembrane transport, 0006836=neurotransmitter transport, 0015893=drug transport" 0016021=integral component of membrane "vacht, Cha's neighbour, VaChT, chn, CG12345, Chn, vAChT, vesicular acetylcholine transporter, CT41182, VACHT, Vacht, VAChT, CG32848, VACht" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain, IPR004734=Multidrug resistance protein" CG32848 16-Dec-15 2015_12 ENSDARG00000006356(slc18a3a) WBGene00006756(unc-17) ENSG00000187714(SLC18A3) "chemical resistant,lethal,hypoactive,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,flight defective,locomotor behavior defective,viable,visible" "mesothoracic extracoxal depressor muscle 66,tormogen cell" FBgn0003227 rec recombination-defective http://flybase.net/reports/FBgn0003227.html "FBgn0038367, FBgn0040563, FBgn0051293" protein_coding_gene "0003677=DNA binding, 0005524=ATP binding, 0004003=ATP-dependent DNA helicase activity" "0007131=reciprocal meiotic recombination, 0006260=DNA replication" "0005656=nuclear pre-replicative complex, 0005657=replication fork" "CG4828, recombination defective, MCM8, rec1, CG31293, mini-chromosome maintenance 8, CG14875, rec-1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR031327=Mini-chromosome maintenance protein, IPR012340=Nucleic acid-binding, OB-fold, IPR001208=MCM domain" CG31293 16-Dec-15 2015_12 ENSMUSG00000027353(Mcm8) ENSG00000125885(MCM8) "sterile,heat sensitive,viable" FBgn0040869 CG15763 http://flybase.net/reports/FBgn0040869.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035941 CG13313 http://flybase.net/reports/FBgn0035941.html protein_coding_gene IPR000859=CUB domain CG13313 16-Dec-15 2015_12 viable DRSC09984 E 0.901828643 -0.468383896 -1.581960268 -0.10091293 -0.007886799 1.117119912 FBgn0060521 l(3)S102409 lethal (3) S102409 http://flybase.net/reports/FBgn0060521.html gene 1024/09 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263900 l(3)B29 http://flybase.net/reports/FBgn0263900.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0086708 stv starvin http://flybase.net/reports/FBgn0086708.html "FBgn0010720, FBgn0036371, FBgn0036370, FBgn0052130" protein_coding_gene "0004252=serine-type endopeptidase activity, 0051087=chaperone binding" "0006497=protein lipidation, 0006508=proteolysis, 0046331=lateral inhibition" "0030018=Z disc, 0005829=cytosol" "CG14108, GH04349, Stv, Starving, Starvin, lethal (3) 00543, CG32130, cg32130, CG10745, l(3)00543, starvin, Dm-Starvin" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR003103=BAG domain" CG32130 16-Dec-15 2015_12 ENSXETG00000009003(BAG4) ENSMUSG00000030847(Bag3) ENSG00000151929(BAG3) FBgn0037943 CG14722 http://flybase.net/reports/FBgn0037943.html protein_coding_gene 0016505=peptidase activator activity involved in apoptotic process 0050829=defense response to Gram-negative bacterium "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site" CG14722 16-Dec-15 2015_12 ENSDARG00000007217(wdr55) ENSMUSG00000042660(Wdr55) ENSG00000120314(WDR55) viable FBgn0028662 VhaPPA1-1 Vacuolar H+ ATPase PPA1 subunit 1 http://flybase.net/reports/FBgn0028662.html FBgn0038278 protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" "0007052=mitotic spindle organization, 0015991=ATP hydrolysis coupled proton transport" "0033181=plasma membrane proton-transporting V-type ATPase complex, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "V-ATPase proton pump, vhaPPA1-1, Vacuolar H[+] ATPase subunit PPA1-1, VhaPPA1-1, CG7007, VhaPPA1" "IPR000245=V-ATPase proteolipid subunit, IPR002379=V-ATPase proteolipid subunit C-like domain" CG7007 16-Dec-15 2015_12 ENSDARG00000031681(atp6v0b) YHR026W(PPA1) WBGene00006913(vha-4) ENSXETG00000003260(atp6v0b) ENSMUSG00000033379(Atp6v0b) ENSG00000117410(ATP6V0B) "lethal,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0260304 GSd460 http://flybase.net/reports/FBgn0260304.html gene 16-Dec-15 2015_12 lethal FBgn0259567 GG01019 http://flybase.net/reports/FBgn0259567.html gene 16-Dec-15 2015_12 visible wing vein L3 FBgn0262714 Sap130 Sin3A-associated protein 130 http://flybase.net/reports/FBgn0262714.html "FBgn0027534, FBgn0010907" protein_coding_gene 0007052=mitotic spindle organization "0005654=nucleoplasm, 0070822=Sin3-type complex" "lethal (3) 06924, SAP130, CG11006, l(3)06924, Sin3A-Associated Protein, BcDNA:LD21213" IPR024137=Histone deacetylase complex subunit SAP130 CG11006 16-Dec-15 2015_12 ENSDARG00000056924(zgc:162722) ENSXETG00000002957(SAP130) ENSMUSG00000024260(Sap130) ENSG00000136715(SAP130) FBgn0038243 CG8066 http://flybase.net/reports/FBgn0038243.html protein_coding_gene 0004869=cysteine-type endopeptidase inhibitor activity IPR000010=Cystatin domain CG8066 16-Dec-15 2015_12 viable DRSC24633 K 0.657644418 -0.293798388 -0.122258226 -0.046606411 0.444985774 2.018870972 FBgn0011982 tRNA:S7:12Ed transfer RNA:ser7:12Ed http://flybase.net/reports/FBgn0011982.html "FBgn0003830, FBgn0011968, FBgn0011979, FBgn0052607, FBgn0060068" tRNA_gene "0033405=UCU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Ser], 777-1, tRNA[[Ser]], tRNA:S, tRNA:ser7, transfer RNA:ser7, 444-3, chrX.trna23-SerAGA, tRNA:S:AGA:AE002593-d, tRNA[Ser][[7]], tRNA:S7, tRNA ser7, CR32607, tRNA:ser, tRNA[[7]][Ser], AE002593.trna14-SerAGA, Ser-tRNA-7, tRNA:ser7:12Ed, transfer RNA:ser" CR32607 16-Dec-15 2015_12 FBgn0001229 Hsp67Bc Heat shock gene 67Bc http://flybase.net/reports/FBgn0001229.html protein_coding_gene "0010998=regulation of translational initiation by eIF2 alpha phosphorylation, 0009408=response to heat, 0006497=protein lipidation, 0031427=response to methotrexate, 0010506=regulation of autophagy" "HSP67Bc, HSPB8, unnamed, HSP67, Hspg3, Gene 3, gene3, gene-3, gene 3, small hsp locus 67B, gene5, Hsp67BC, CG4190, Hsp-G3, Dm-HSP67Bc, hsp67B" "IPR008978=HSP20-like chaperone, IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain, IPR031107=Small heat shock protein HSP20" CG4190 16-Dec-15 2015_12 "WBGene00004798(sip-1),WBGene00002020(hsp-16.49),WBGene00002015(hsp-16.1),WBGene00002018(hsp-16.41),WBGene00002016(hsp-16.2),WBGene00008592(F08H9.4)" " larval stage--pupal stage , prepupal stage , embryonic stage | >= 7hr " "viable,fertile" FBgn0015818 Spx Spliceosomal protein on the X http://flybase.net/reports/FBgn0015818.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" "0022008=neurogenesis, 0007052=mitotic spindle organization, 0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005686=U2 snRNP" "CG3780, spx, SPX" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG3780 16-Dec-15 2015_12 ENSDARG00000018574(sf3b4) YOR319W(HSH49) WBGene00004723(sap-49) ENSXETG00000011038(sf3b4) ENSMUSG00000068856(Sf3b4) ENSG00000143368(SF3B4) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18720 K -0.67781696 0.175211295 -0.166514163 -0.076534338 -1.865229689 -1.261625145 FBgn0277431 l(3)psg17 http://flybase.net/reports/FBgn0277431.html gene psg17 16-Dec-15 2015_12 FBgn0260104 2L3191 http://flybase.net/reports/FBgn0260104.html gene 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,somatic clone" FBgn0036063 CG6674 http://flybase.net/reports/FBgn0036063.html protein_coding_gene IPR029338=Tumour suppressing sub-chromosomal transferable candidate 4 CG6674 16-Dec-15 2015_12 viable FBgn0051946 tRNA:CR31946 transfer RNA:CR31946 http://flybase.net/reports/FBgn0051946.html FBgn0060073 tRNA_gene 0033447=AGA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31946, chr2L.trna5-ArgTCT, AE002638.trna12-ArgTCT, tRNA:R:TCT:AE002638-b" CR31946 16-Dec-15 2015_12 FBgn0010645 l(2)08014 lethal (2) 08014 http://flybase.net/reports/FBgn0010645.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259728 CG42382 http://flybase.net/reports/FBgn0259728.html FBgn0003194 protein_coding_gene 0046872=metal ion binding 0006281=DNA repair CG8016 "IPR000571=Zinc finger, CCCH-type" CG42382 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0035649 CG10483 http://flybase.net/reports/FBgn0035649.html protein_coding_gene 0016021=integral component of membrane "IPR004331=SPX domain, IPR004342=EXS, C-terminal" CG10483 16-Dec-15 2015_12 "ENSDARG00000029671(si:dkey-60b12.7),ENSDARG00000062449(si:dkey-6n6.7)" YIL047C(SYG1) WBGene00012659(Y39A1A.22) ENSXETG00000023134(xpr1) ENSMUSG00000026469(Xpr1) ENSG00000143324(XPR1) "viable,fertile" FBgn0034054 CG8366 http://flybase.net/reports/FBgn0034054.html protein_coding_gene "0003677=DNA binding, 0004518=nuclease activity" "IPR011335=Restriction endonuclease type II-like, IPR019080=YqaJ viral recombinase, IPR011604=Exonuclease, phage-type/RecB, C-terminal" CG8366 16-Dec-15 2015_12 viable DRSC07153 I 0.538364737 1.529012203 0.973629552 1.034407923 0.326281002 0.314302639 FBgn0031883 Caper Caper http://flybase.net/reports/FBgn0031883.html protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0008380=RNA splicing, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0070374=positive regulation of ERK1 and ERK2 cascade, 0000398=mRNA splicing, via spliceosome, 0046579=positive regulation of Ras protein signal transduction" "0071013=catalytic step 2 spliceosome, 0005654=nucleoplasm, 0005681=spliceosomal complex, 0005634=nucleus, 0071011=precatalytic spliceosome" "CG11266, CC1.3, Caper, HCC1, CAPER, cg11266" "IPR029123=Splicing factor RBM39, linker, IPR000504=RNA recognition motif domain, IPR006509=Splicing factor, RBM39-like, IPR012677=Nucleotide-binding alpha-beta plait domain" CG11266 16-Dec-15 2015_12 "ENSDARG00000011613(rbm39a),ENSDARG00000041853(rbm39b)" WBGene00021921(Y55F3AM.3) ENSXETG00000007434(rnpc2) ENSMUSG00000027620(Rbm39) ENSG00000131051(RBM39) "viable,visible" trichogen cell DRSC02137 EK 0.549039671 0.567433218 -0.139840001 1.841334739 -2.366422357 -1.697928933 FBgn0086071 snoRNA:Or-CD11b http://flybase.net/reports/FBgn0086071.html snoRNA_gene "CR34700, Or-cd11b" CR34700 16-Dec-15 2015_12 FBgn0037448 CG15186 http://flybase.net/reports/FBgn0037448.html protein_coding_gene CG15186 16-Dec-15 2015_12 FBgn0065738 l(2)SH0531 lethal (2) SH0531 http://flybase.net/reports/FBgn0065738.html gene l(2)SH2 0531 16-Dec-15 2015_12 "lethal,recessive" FBgn0014987 l(2)46Dc lethal (2) 46Dc http://flybase.net/reports/FBgn0014987.html gene "IX, Group IX" 16-Dec-15 2015_12 lethal FBgn0051067 CG31067 http://flybase.net/reports/FBgn0051067.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264278 Su(Mir)1E2-4 http://flybase.net/reports/FBgn0264278.html gene 16-Dec-15 2015_12 FBgn0085310 CG34281 http://flybase.net/reports/FBgn0085310.html protein_coding_gene CG14328 CG34281 16-Dec-15 2015_12 viable FBgn0005521 l(2)37Fh lethal (2) 37Fh http://flybase.net/reports/FBgn0005521.html gene l(2)C188 16-Dec-15 2015_12 lethal FBgn0064180 htz hitzschlag http://flybase.net/reports/FBgn0064180.html gene 0008344=adult locomotory behavior 16-Dec-15 2015_12 FBgn0003241 rf roof wings http://flybase.net/reports/FBgn0003241.html gene 16-Dec-15 2015_12 wing FBgn0034490 CG9864 http://flybase.net/reports/FBgn0034490.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane CT27832 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG9864 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" viable FBgn0005199 l(3)ac lethal (3) accessory http://flybase.net/reports/FBgn0005199.html gene 16-Dec-15 2015_12 lethal FBgn0024530 l(3)L0499 lethal (3) L0499 http://flybase.net/reports/FBgn0024530.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260382 GSd462 http://flybase.net/reports/FBgn0260382.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038977 CG5376 http://flybase.net/reports/FBgn0038977.html protein_coding_gene CG5376 16-Dec-15 2015_12 viable "germline cell,male" FBgn0265347 CR44301 http://flybase.net/reports/FBgn0265347.html non_protein_coding_gene CR44301 16-Dec-15 2015_12 FBgn0062685 EP1509 EP1509 http://flybase.net/reports/FBgn0062685.html gene EP(X)1509 16-Dec-15 2015_12 FBgn0082940 snoRNA:Me28S-C3227a snoRNA:Me28S-C3227a http://flybase.net/reports/FBgn0082940.html snoRNA_gene "Me28S-C3227a, Me28S-Cm3227a, CR34533" CR34533 16-Dec-15 2015_12 FBgn0053802 His-ë¬:CR33802 His-ë¬:CR33802 http://flybase.net/reports/FBgn0053802.html pseudogene_attribute CR33802 CR33802 16-Dec-15 2015_12 FBgn0036272 CG4300 http://flybase.net/reports/FBgn0036272.html FBgn0062047 protein_coding_gene "0016768=spermine synthase activity, 0004766=spermidine synthase activity" "0008295=spermidine biosynthetic process, 0006597=spermine biosynthetic process" anon-WO0118547.387 "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR015576=Spermine synthase, animal, IPR001045=Spermidine/spermine synthases, IPR030374=Polyamine biosynthesis domain" CG4300 16-Dec-15 2015_12 ENSDARG00000008155(sms) ENSXETG00000003857(SMS) ENSMUSG00000071708(Sms) ENSG00000102172(SMS) "viable,fertile" FBgn0030938 CG15047 http://flybase.net/reports/FBgn0030938.html protein_coding_gene "IPR009060=UBA-like, IPR015940=Ubiquitin-associated domain" CG15047 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0026659 l(2)17E1 lethal (2) 17E1 http://flybase.net/reports/FBgn0026659.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0259590 B0756 http://flybase.net/reports/FBgn0259590.html gene 16-Dec-15 2015_12 visible "anterior crossvein,submarginal cell,wing vein" FBgn0027186 l(2)60A-F lethal (2) 60A-F http://flybase.net/reports/FBgn0027186.html gene 16-Dec-15 2015_12 "wild-type,lethal,recessive" FBgn0025343 anon-25Dd anon-25Dd http://flybase.net/reports/FBgn0025343.html gene 0003725=double-stranded RNA binding #6 16-Dec-15 2015_12 FBgn0031574 CG3964 http://flybase.net/reports/FBgn0031574.html protein_coding_gene 0004835=tubulin-tyrosine ligase activity "0022008=neurogenesis, 0018095=protein polyglutamylation" "IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027748=Tubulin polyglutamylase TTLL-4" CG3964 16-Dec-15 2015_12 WBGene00014232(ttll-4) ENSXETG00000013887(TTLL4) ENSMUSG00000033257(Ttll4) ENSG00000135912(TTLL4) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0011147 l(1)Q223 lethal (1) Q223 http://flybase.net/reports/FBgn0011147.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0277417 l(3)psg8 http://flybase.net/reports/FBgn0277417.html gene psg8 16-Dec-15 2015_12 FBgn0027348 bgm bubblegum http://flybase.net/reports/FBgn0027348.html "FBgn0027881, FBgn0028908" protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity "0001676=long-chain fatty acid metabolic process, 0034976=response to endoplasmic reticulum stress" "BG:DS01514.2, Bubblegum, Bgm, unnamed, BG:DS0514.2, 2a9hom, CG4501" IPR000873=AMP-dependent synthetase/ligase CG4501 16-Dec-15 2015_12 "ENSDARG00000062077(LOC100006023),ENSDARG00000004094(acsbg2)" "ENSXETG00000009756(ACSBG1),ENSXETG00000021876(ACSBG2)" "ENSMUSG00000032281(Acsbg1),ENSMUSG00000024207(Acsbg2)" "ENSG00000130377(ACSBG2),ENSG00000103740(ACSBG1)" "viable,fertile,aging defective,recessive,visual behavior defective,lethal,partially lethal - majority die,visible" "optic lobe,lamina,retina & cell body,photoreceptor cell & axon,mesothoracic tergum" DRSC03495 IEK -2.103706258 -0.789295605 1.458442373 -3.034931862 1.596038381 1.65697295 FBgn0011586 e(r) enhancer of rudimentary http://flybase.net/reports/FBgn0011586.html FBgn0030068 protein_coding_gene "0006357=regulation of transcription from RNA polymerase II promoter, 0045747=positive regulation of Notch signaling pathway, 0006221=pyrimidine nucleotide biosynthetic process, 0007049=cell cycle" 0005634=nucleus "ER, ER_DROME, CG1871" IPR000781=Enhancer of rudimentary CG1871 16-Dec-15 2015_12 ENSDARG00000032866(erh) WBGene00011892(T21C9.4) ENSXETG00000017914(ERH) ENSMUSG00000021131(Erh) ENSG00000100632(ERH) " adult stage | female , adult stage | male " "viable,fertile,wild-type,partially lethal - majority live,visible" trichogen cell FBgn0020058 E(wa)706 E(wa)706 http://flybase.net/reports/FBgn0020058.html gene E706 16-Dec-15 2015_12 "lethal,recessive,eye color defective" pigment cell FBgn0262437 mir-274 mir-274 stem loop http://flybase.net/reports/FBgn0262437.html "FBgn0067720, FBgn0262289" miRNA_gene "miR-274, mir-274, dme-mir-274, CR33582, CR42996, dme-miR-274" CR42996 16-Dec-15 2015_12 "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "wing,eye" FBgn0016021 l(3)85Ak lethal (3) 85Ak http://flybase.net/reports/FBgn0016021.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043040 l(2)42Ba lethal (2) 42Ba http://flybase.net/reports/FBgn0043040.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0084840 l(3)S023901 l(3)S023901 http://flybase.net/reports/FBgn0084840.html gene 16-Dec-15 2015_12 FBgn0265152 CR44221 http://flybase.net/reports/FBgn0265152.html non_protein_coding_gene CR44221 16-Dec-15 2015_12 FBgn0035210 msd5 mitotic spindle density 5 http://flybase.net/reports/FBgn0035210.html protein_coding_gene "0007052=mitotic spindle organization, 0090307=mitotic spindle assembly" "0005875=microtubule associated complex, 0070652=HAUS complex" "msd5, mitotic spindle density 5, Dgt7, CG2213" CG2213 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0037102 CRIF CR6-interacting factor http://flybase.net/reports/FBgn0037102.html FBgn0062099 protein_coding_gene "0007049=cell cycle, 1900370=positive regulation of RNA interference, 1903705=positive regulation of production of siRNA involved in RNA interference, 0098586=cellular response to virus" "0048471=perinuclear region of cytoplasm, 0005634=nucleus" "anon-WO0118547.316, dCRIF, CG7172" IPR018472=Growth arrest/ DNA-damage-inducible protein-interacting protein 1 CG7172 16-Dec-15 2015_12 ENSDARG00000039338(LOC402803) WBGene00010616(K07A1.10) ENSMUSG00000033751(Gadd45gip1) ENSG00000179271(GADD45GIP1) "viable,visible" trichogen cell FBgn0001933 l(2)25Ef lethal (2) 25Ef http://flybase.net/reports/FBgn0001933.html gene "l(2)gdh10, l(2)jf30, jf30, l(2)gdh-10" 16-Dec-15 2015_12 "lethal,recessive" FBgn0029093 cathD cathD http://flybase.net/reports/FBgn0029093.html FBgn0033227 protein_coding_gene 0004190=aspartic-type endopeptidase activity "0048102=autophagic cell death, 0050829=defense response to Gram-negative bacterium, 0035071=salivary gland cell autophagic cell death, 0006508=proteolysis, 0045476=nurse cell apoptotic process, 0006915=apoptotic process" "0005576=extracellular region, 0005764=lysosome, 0005875=microtubule associated complex" "Cathepsin-D, CATH, CG1548, cathepsin D, CathD, Cathepsin D, CT3996, T17, CTSD" "IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain, IPR001461=Aspartic peptidase, IPR012848=Aspartic peptidase, N-terminal" CG1548 16-Dec-15 2015_12 "ENSDARG00000057698(ctsd),ENSDARG00000009313(zgc:63831)" YPL154C(PEP4) WBGene00000217(asp-4) "ENSXETG00000024956(ctsd),ENSXETG00000024953(BC096630.1),ENSXETG00000024954(),ENSXETG00000004611(),ENSXETG00000002892(ctsd-2)" ENSMUSG00000007891(Ctsd) ENSG00000117984(CTSD) "viable,fertile,increased cell death,conditional,cell death defective,decreased cell death" "adult brain,conditional,egg chamber,nurse cell,eye,spermatogonial cyst,male germline cell" FBgn0027147 l(3)71CDc lethal (3) 71CDc http://flybase.net/reports/FBgn0027147.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060349 l(3)S142215b lethal (3) S142215b http://flybase.net/reports/FBgn0060349.html gene 1422/15 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0038738 CG4572 http://flybase.net/reports/FBgn0038738.html FBgn0066050 protein_coding_gene 0004185=serine-type carboxypeptidase activity "0033227=dsRNA transport, 0006508=proteolysis" "CT14806, anon-WO02059370.13" "IPR018202=Peptidase S10, serine carboxypeptidase, active site, IPR029058=Alpha/Beta hydrolase fold, IPR001563=Peptidase S10, serine carboxypeptidase" CG4572 16-Dec-15 2015_12 ENSDARG00000056480(cpvl) "YBR139W(),YMR297W(PRC1)" "WBGene00017969(F32A5.3),WBGene00007462(C08H9.1),WBGene00018271(F41C3.5),WBGene00008741(F13D12.6),WBGene00019605(K10B2.2),WBGene00021503(Y40D12A.2)" ENSXETG00000012046(cpvl) ENSMUSG00000052955(Cpvl) ENSG00000106066(CPVL) "viable,fertile" FBgn0015826 T-C9.12 T-C9.12 http://flybase.net/reports/FBgn0015826.html gene 16-Dec-15 2015_12 FBgn0259957 CG42467 http://flybase.net/reports/FBgn0259957.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42467 16-Dec-15 2015_12 FBgn0011482 l(3)neo49 lethal (3) neo49 http://flybase.net/reports/FBgn0011482.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082611 aact anti-activin http://flybase.net/reports/FBgn0082611.html gene 0007179=transforming growth factor beta receptor signaling pathway AACT 16-Dec-15 2015_12 FBgn0265556 12.95 http://flybase.net/reports/FBgn0265556.html gene 16-Dec-15 2015_12 learning defective FBgn0004018 wo white ocelli http://flybase.net/reports/FBgn0004018.html gene 16-Dec-15 2015_12 "visible,recessive" ocellus pigment granule FBgn0002327 l(3)86Ff lethal (3) 86Ff http://flybase.net/reports/FBgn0002327.html gene "l(3)ck6, ck6, l(3)S063512" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0259639 B1211 http://flybase.net/reports/FBgn0259639.html gene 16-Dec-15 2015_12 visible "tarsal segment,unguis" FBgn0016732 SR3-2 Suppressor of Ras85D 3-2 http://flybase.net/reports/FBgn0016732.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067745 l(1)G0265 lethal (1) G0265 http://flybase.net/reports/FBgn0067745.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0017628 Eig44C Eig44C http://flybase.net/reports/FBgn0017628.html gene "Eig44, Ecdysone-induced gene 44C" 16-Dec-15 2015_12 FBgn0003302 rux roughex http://flybase.net/reports/FBgn0003302.html protein_coding_gene "0051726=regulation of cell cycle, 0000278=mitotic cell cycle, 0007096=regulation of exit from mitosis, 0040020=regulation of meiotic nuclear division, 0007455=eye-antennal disc morphogenesis, 0007088=regulation of mitotic nuclear division, 0048749=compound eye development" 0005634=nucleus "Rux, Roughex, CG4336, Rough-ex" IPR009259=Drosophila roughex CG4336 16-Dec-15 2015_12 " embryonic stage , larval stage , adult stage , larval stage && adult stage " imaginal disc

"viable,locomotor behavior defective,fertile,visible,recessive,male sterile,cytokinesis defective,wild-type,mitotic cell cycle defective" "eye,cyst cell,Nebenkern,onion stage spermatid,mitotic cell cycle,photoreceptor cell,S phase | ectopic,eye disc,photoreceptor cell R8" FBgn0267902 CR46190 http://flybase.net/reports/FBgn0267902.html pseudogene_attribute CG12717-related CR46190 16-Dec-15 2015_12 FBgn0259311 EP-M32 http://flybase.net/reports/FBgn0259311.html gene 16-Dec-15 2015_12 visible wing vein FBgn0259591 B0771 http://flybase.net/reports/FBgn0259591.html gene 16-Dec-15 2015_12 visible "macrochaeta,supernumerary" FBgn0065380 l(2)SH1667 lethal (2) SH1667 http://flybase.net/reports/FBgn0065380.html gene l(2)SH2 1667 16-Dec-15 2015_12 "lethal,recessive" FBgn0031728 Hsp60C Hsp60C http://flybase.net/reports/FBgn0031728.html protein_coding_gene 0005524=ATP binding "0007301=female germline ring canal formation, 0006457=protein folding, 0006626=protein targeting to mitochondrion, 0030707=ovarian follicle cell development, 0006458='de novo' protein folding, 0048477=oogenesis, 0042026=protein refolding, 0007424=open tracheal system development, 0007283=spermatogenesis" "0005759=mitochondrial matrix, 0005739=mitochondrion" "CG7235, bs36d10.y1, A4V087_DROME" "IPR027413=GroEL-like equatorial domain, IPR001844=Chaperonin Cpn60, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR018370=Chaperonin Cpn60, conserved site, IPR027409=GroEL-like apical domain" CG7235 16-Dec-15 2015_12 ENSDARG00000056160(hspd1) YLR259C(HSP60) WBGene00002025(hsp-60) ENSXETG00000007509(HSPD1) ENSMUSG00000025980(Hspd1) ENSG00000144381(HSPD1) "sterile,flight defective,partially lethal - majority die,some die during first instar larval stage,viable" "embryonic/larval trachea,eye,antenna,macrochaeta,testis,seminal vesicle" DRSC29438 K 0.475078311 -0.175850628 -0.115676115 -0.299778593 0.635373882 -1.624587631 FBgn0259662 B0572 http://flybase.net/reports/FBgn0259662.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0001362 l(1)1Fa lethal (1) 1Fa http://flybase.net/reports/FBgn0001362.html gene 16-Dec-15 2015_12 lethal FBgn0051718 Ir31a Ionotropic receptor 31a http://flybase.net/reports/FBgn0051718.html protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity" 0050907=detection of chemical stimulus involved in sensory perception "0016021=integral component of membrane, 0016020=membrane" "DmelIR31a, ionotropic receptor 31a, CG31718, IR31a" IPR001320=Ionotropic glutamate receptor CG31718 16-Dec-15 2015_12 "viable,fertile" FBgn0262842 CG43206 http://flybase.net/reports/FBgn0262842.html protein_coding_gene "0009055=electron carrier activity, 0008121=ubiquinol-cytochrome-c reductase activity" chr3L_16559870_16560394.0 "IPR015089=Cytochrome b-c1 complex subunit 10, IPR029027=Single alpha-helix domain" CG43206 16-Dec-15 2015_12 FBgn0035150 Rev1 Rev1 http://flybase.net/reports/FBgn0035150.html protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0017125=deoxycytidyl transferase activity, 0003684=damaged DNA binding, 0000287=magnesium ion binding" "0019985=translesion synthesis, 0010569=regulation of double-strand break repair via homologous recombination, 0006281=DNA repair" "DmRev1, UV-revertible gene 1, dREV1, rev1, AAF47401, CG12189, DmREV1, drev1, REV1, dRev1" "IPR001126=UmuC domain, IPR001357=BRCT domain, IPR017961=DNA polymerase, Y-family, little finger domain, IPR012112=DNA repair protein, Rev1" CG12189 16-Dec-15 2015_12 ENSDARG00000018296(si:dkey-57a22.7) YOR346W(REV1) WBGene00014066(rev-1) ENSXETG00000019375(REV1) ENSMUSG00000026082(Rev1) ENSG00000135945(REV1) "radiation sensitive,viable" FBgn0020814 l(3)L3999 lethal (3) L3999 http://flybase.net/reports/FBgn0020814.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027334 l(1)G0004 lethal (1) G0004 http://flybase.net/reports/FBgn0027334.html FBgn0031105 protein_coding_gene "0003729=mRNA binding, 0003723=RNA binding" 0022008=neurogenesis 0005730=nucleolus "CG11738, unnamed, l(G0004)" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG11738 16-Dec-15 2015_12 ENSDARG00000008502(pno1) YOR145C(PNO1) WBGene00013144(Y53C12B.2) ENSXETG00000017349(BC077670.1) ENSMUSG00000020116(Pno1) ENSG00000115946(PNO1) "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0024842 per::Dpse\per per http://flybase.net/reports/FBgn0024842.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0004019 wobA wobbly A http://flybase.net/reports/FBgn0004019.html gene 16-Dec-15 2015_12 uncoordinated FBgn0051471 tRNA:CR31471 transfer RNA:CR31471 http://flybase.net/reports/FBgn0051471.html FBgn0060047 tRNA_gene 0033437=ACU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA[[Thr]], chr3R.trna28-ThrAGT, CR31471, AE002708.trna22-ThrAGT, tRNA:T:AGT:AE002708-b" CR31471 16-Dec-15 2015_12 FBgn0035687 CG13296 http://flybase.net/reports/FBgn0035687.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG13296 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0265017 CR43751 http://flybase.net/reports/FBgn0265017.html "FBgn0264082, FBgn0031394" non_protein_coding_gene "CG15383, CG43751" CR43751 16-Dec-15 2015_12 FBgn0058209 CG40209 http://flybase.net/reports/FBgn0058209.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011431 l(3)j11B2 lethal (3) j11B2 http://flybase.net/reports/FBgn0011431.html FBgn0024524 gene l(3)j3E5 16-Dec-15 2015_12 "lethal,recessive" FBgn0038427 ema endosomal maturation defective http://flybase.net/reports/FBgn0038427.html protein_coding_gene "0016197=endosomal transport, 0008333=endosome to lysosome transport" "0016021=integral component of membrane, 0005770=late endosome" CG12753 IPR019155=Uncharacterised protein family FPL CG12753 16-Dec-15 2015_12 ENSDARG00000038094(zgc:56230) WBGene00001660(gop-1) ENSXETG00000024095(CLEC16A) ENSMUSG00000068663(Clec16a) ENSG00000038532(CLEC16A) "neuroanatomy defective,recessive,lethal - all die before end of P-stage,some die during P-stage,viable" "terminal bouton,endosome,terminal boutonExel7330),neuromuscular junctionExel7330)" FBgn0003716 tkv thickveins http://flybase.net/reports/FBgn0003716.html FBgn0010572 protein_coding_gene "0005025=transforming growth factor beta receptor activity, type I, 0004702=receptor signaling protein serine/threonine kinase activity, 0050431=transforming growth factor beta binding, 0004672=protein kinase activity, 0005524=ATP binding, 0005515=protein binding" "0007424=open tracheal system development, 0006468=protein phosphorylation, 0045705=negative regulation of salivary gland boundary specification, 0008101=decapentaplegic signaling pathway, 0030509=BMP signaling pathway, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0009953=dorsal/ventral pattern formation, 0045570=regulation of imaginal disc growth, 0010629=negative regulation of gene expression, 0007179=transforming growth factor beta receptor signaling pathway, 0030707=ovarian follicle cell development, 0030721=spectrosome organization, 0007391=dorsal closure, 0001745=compound eye morphogenesis, 0007304=chorion-containing eggshell formation, 0030718=germ-line stem cell maintenance, 0006357=regulation of transcription from RNA polymerase II promoter, 0007181=transforming growth factor beta receptor complex assembly, 0001763=morphogenesis of a branching structure, 0007448=anterior/posterior pattern specification, imaginal disc, 0045595=regulation of cell differentiation, 0042078=germ-line stem cell division, 0008582=regulation of synaptic growth at neuromuscular junction, 0008354=germ cell migration, 0060799=transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification, 0007274=neuromuscular synaptic transmission, 0007476=imaginal disc-derived wing morphogenesis, 0061327=anterior Malpighian tubule development, 0048636=positive regulation of muscle organ development, 0022407=regulation of cell-cell adhesion, 0016477=cell migration, 0035215=genital disc development, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0048100=wing disc anterior/posterior pattern formation, 0007507=heart development, 0007488=histoblast morphogenesis, 0090254=cell elongation involved in imaginal disc-derived wing morphogenesis, 0045927=positive regulation of growth" "0005886=plasma membrane, 0005771=multivesicular body, 0005769=early endosome, 0035230=cytoneme, 0005829=cytosol" "l(2)25Da, Thick Veins, thickvein, tkva, Dtfr, Thick-vein, Brk25D, slater, STK-A, Activin-A-receptor-25D, Brk25D1, Atkv, DPP receptor, dtfr, Atr25D, Thick veins, Brk25D2, Thickvein, TKV, TKV1, Thickveins, kv, Thick-veins, Tkv, thick veins, str, l(2)04415, tkv1, CG14026, BMP receptor kinase 25D" "IPR017441=Protein kinase, ATP binding site, IPR003605=GS domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR000472=Activin types I and II receptor domain, IPR000333=Ser/Thr protein kinase, TGFB receptor" CG14026 16-Dec-15 2015_12 "ENSDARG00000045097(bmpr1ab),ENSDARG00000019728(bmpr1aa)" WBGene00004860(sma-6) "ENSXETG00000019220(BMPR1B),ENSXETG00000003655(bmpr1a)" "ENSMUSG00000052430(Bmpr1b),ENSMUSG00000021796(Bmpr1a)" "ENSG00000138696(BMPR1B),ENSG00000107779(BMPR1A)" " embryonic stage | stage 16 , larval stage , embryonic stage , embryonic stage | stage 9 , embryonic stage | stage 1-4 , embryonic stage | syncytial blastoderm , embryonic stage | stage 6 , embryonic stage | stage 6,7 , embryonic stage | stage 13-16 , embryonic stage | early , embryonic stage | stage 7 , embryonic stage | stage 5 , embryonic stage | 0-12hr , embryonic stage | stage 6-9 , embryonic stage | stage 3,4 , embryonic stage | stage >=12 , embryonic stage | stage 11-12 , embryonic stage | stage 11 , embryonic stage | stage 10 , larval stage | third instar , adult stage && oogenesis stage , embryonic stage | stage >12 , embryonic stage | stage 8 , embryonic stage | stage 6-12 , embryonic stage | cellular blastoderm , embryonic stage | stage 12-17 " " gastric caecum

, imaginal disc

, organism

, midgut chamber 4

, morphogenetic furrow

, embryonic/larval proventriculus

, midgut chamber 1

, mesoderm

,

ubiquitous , dorsal mesothoracic disc

, organism | pair rule

, mesoderm | ventral

, posterior embryonic/larval midgut

, eye-antennal disc

, midgut constriction 1

, ectoderm | lateral

, ventral thoracic disc

, ectoderm | dorsal

, embryonic/larval pharynx

,

dorsal ventral gradient , posterior midgut proper primordium

, tracheal pit

, anterior midgut proper primordium

, tracheal primordium

, embryonic/larval hindgut

, dorsal mesothoracic disc | restricted

, nurse cell

, anterior embryonic/larval midgut

, visceral mesoderm

, ventral neurogenic region

, epidermis | dorsal

, centripetally migrating follicle cell

,

pair rule , embryonic/larval midgut

" "visible,dominant,viable,fertile,lethal,recessive,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,wild-type,semidominant,heat sensitive,germline clone,neurophysiology defective,mitotic cell cycle defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,cell lethalcell lethal,partially lethal - majority die,cell autonomous,maternal effect,RU486 conditional,increased cell number,cell non-autonomous,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,female sterile,cell shape defective,hyperplasia,female limited,sterile,male limited,circadian rhythm defective" "submarginal cell,1st posterior cell,,wing,wing vein,embryonic/first instar larval cuticle,sex comb,ventral thoracic disc,leg,bouton,neuromuscular junction,dorsal appendage,egg operculum,filzkorper,embryonic dorsal epidermis,dorsal triple row,medial triple row,ventral triple row,embryo,eye,wing disc,scutum,embryonic head,abdominal segment,eye disc,embryonic epidermis,peripodial epithelium,wing margin,anterior crossvein,posterior crossvein,cephalopharyngeal skeleton,midgut constriction,gastric caecum,trachea,embryonic/larval dorsal branch 1,embryonic/larval dorsal branch 2,embryonic/larval dorsal branch 3,embryonic/larval dorsal branch 4,embryonic/larval dorsal branch 5,embryonic/larval dorsal branch 6,embryonic/larval dorsal branch 7,embryonic/larval dorsal branch 8,embryonic/larval dorsal branch 9,embryonic/larval dorsal branch 10,ganglionic branch 0,ganglionic branch 1,ganglionic branch 2,ganglionic branch 3,ganglionic branch 4,ganglionic branch 5,ganglionic branch 6,ganglionic branch 7,ganglionic branch 8,ganglionic branch 9,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval trachea,ommatidium,female germline stem cell,male germline stem cell,embryonic/larval tracheal system,stage 13 embryo,stage 14 embryo,stage 15 embryo,amnioserosa,filamentous actin,secondary pigment cell,adult midgut precursor cell,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,adult thorax,genital disc primordium,synapse,t-bar,embryonic/larval dorsal vessel,crystal cell,Malpighian tubule,dorsal closure embryo,morphogenetic furrow,testis,abdominal ventral denticle belt,telson,visceral mesoderm,presumptive embryonic salivary gland,histoblast,histoblast nest,crossvein,air sac primordium |,scutellar bristle,wing blade,abdomen,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,NMJ bouton,adult brain,macrochaeta,sensory mother cell,tsh-Gal4-1,hs.PB,wing cell,btl.PS,dorsal trunk primordium,btl.B123,embryonic/larval neuromuscular junction,egg chamber,tracheocyte,embryonic/larval dorsal trunk,dorsal branch primordium,embryonic/larval muscle system,embryonic/larval visceral branch,tracheal pit,wing pouch,genitalia,analia,wing margin bristle,apoptotic amnioserosa,germline cell,hub cell,pericardial cell,mesoderm,epidermal cell,cell cycle,wing disc |,ovary,cystoblast,2nd posterior cell,dil cell,wing sensillum,wing | prepupal stage,haltere,mesothoracic tergum,retina | pupal stage P6,adherens junction,inter-ommatidial precursor cell,germarium,female germline cell" FBgn0267562 CR45902 http://flybase.net/reports/FBgn0267562.html non_protein_coding_gene CR45902 16-Dec-15 2015_12 FBgn0267254 CG45690 http://flybase.net/reports/FBgn0267254.html protein_coding_gene CG45690 16-Dec-15 2015_12 FBgn0050377 CG30377 http://flybase.net/reports/FBgn0050377.html "FBgn0033231, FBgn0040779" protein_coding_gene 0055070=copper ion homeostasis "CG1918, CG14595" CG30377 16-Dec-15 2015_12 "viable,fertile,lethal" FBgn0022128 l(2)k06416 lethal (2) k06416 http://flybase.net/reports/FBgn0022128.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011062 l(1)Q15 lethal (1) Q15 http://flybase.net/reports/FBgn0011062.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0001540 l(1)14DEb lethal (1) 14DEb http://flybase.net/reports/FBgn0001540.html gene l(1)l 16-Dec-15 2015_12 "lethal,recessive" FBgn0062566 Mod(var)E69 Mod(var)E69 http://flybase.net/reports/FBgn0062566.html gene 0006342=chromatin silencing E69 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,suppressor of variegation,viable" FBgn0019806 h::sc h::sc http://flybase.net/reports/FBgn0019806.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0041582 tamo tamo http://flybase.net/reports/FBgn0041582.html FBgn0034980 protein_coding_gene "0005515=protein binding, 0008139=nuclear localization sequence binding, 0008270=zinc ion binding, 0008536=Ran GTPase binding" "0042308=negative regulation of protein import into nucleus, 0007275=multicellular organismal development, 0015031=protein transport" 0005737=cytoplasm "60B, CG4057" "IPR029746=Protein tamozhennic, IPR001876=Zinc finger, RanBP2-type, IPR018997=PUB domain" CG4057 16-Dec-15 2015_12 ENSDARG00000068814(si:dkey-238o13.3) "female sterile,lethal,partially,viable" "embryonic dorsal epidermis,filzkorper,denticle belt,egg chamber" FBgn0010278 Ssrp Structure specific recognition protein http://flybase.net/reports/FBgn0010278.html FBgn0005644 protein_coding_gene "0031491=nucleosome binding, 0003727=single-stranded RNA binding, 0031492=nucleosomal DNA binding, 0000217=DNA secondary structure binding, 0003697=single-stranded DNA binding, 0043621=protein self-association, 0005515=protein binding" "0051101=regulation of DNA binding, 0022008=neurogenesis, 0001672=regulation of chromatin assembly or disassembly" "0035101=FACT complex, 0005634=nucleus, 0005730=nucleolus" "Cf5, Chorion factor, SSRP, dSSRP, ssrp, dSSRP1, DssRP, SSRP1, CG4817, dSsrp, structure-specific recognition protein" "IPR000969=Structure-specific recognition protein, IPR013719=Domain of unknown function DUF1747, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR024954=SSRP1 domain, IPR009071=High mobility group box domain" CG4817 16-Dec-15 2015_12 "ENSDARG00000037397(ssrp1a),ENSDARG00000016994(ssrp1b)" YML069W(POB3) "WBGene00001974(hmg-4),WBGene00001973(hmg-3)" ENSMUSG00000027067(Ssrp1) ENSG00000149136(SSRP1) " oogenesis stage && adult stage | female , adult stage && oogenesis stage " " ovary

, nurse cell

" "lethal - all die during pharate adult stage,lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,antenna,head capsule,eye-antennal disc,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC04658 IE -3.67644009 -3.621707834 -1.920941941 -2.251911414 0.210811842 -0.555188344 FBgn0030945 Ing3 "Inhibitor of growth family, member 3" http://flybase.net/reports/FBgn0030945.html protein_coding_gene 0008270=zinc ion binding "0043486=histone exchange, 0016573=histone acetylation" "0035267=NuA4 histone acetyltransferase complex, 0000123=histone acetyltransferase complex, 0005634=nucleus" "ING3, CG6632, dIng3, dIng3~, Ing3" "IPR001965=Zinc finger, PHD-type, IPR024610=Inhibitor of growth protein, N-terminal histone-binding, IPR028651=ING family, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG6632 16-Dec-15 2015_12 "YHR090C(YNG2),YNL097C(PHO23)" WBGene00013095(ing-3) "viable,fertile" DRSC27959 EK -0.20937189 0.121195181 2.591371594 -0.420961652 -1.723706771 -1.52375965 FBgn0065566 l(2)SH0978 lethal (2) SH0978 http://flybase.net/reports/FBgn0065566.html gene l(2)SH2 0978 16-Dec-15 2015_12 "lethal,recessive" FBgn0041123 l(2)45Bd lethal (2) 45Bd http://flybase.net/reports/FBgn0041123.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000027 acj3 abnormal chemosensory jump 3 http://flybase.net/reports/FBgn0000027.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive" FBgn0004593 Eig71Ef Ecdysone-induced gene 71Ef http://flybase.net/reports/FBgn0004593.html protein_coding_gene "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0042742=defense response to bacterium" 0005576=extracellular region "Gene V, 71E-Gene-V, V, L71, gene V, CG7599, gene-V, L71-5, EIG71-EF" IPR003475=Insect protein of unknown function CG7599 16-Dec-15 2015_12 FBgn0030679 CG8206 http://flybase.net/reports/FBgn0030679.html protein_coding_gene 0008270=zinc ion binding "IPR007853=Zinc finger, DNL-type, IPR024158=Mitochondrial import protein TIM15" CG8206 16-Dec-15 2015_12 ENSMUSG00000075467(Dnlz) viable FBgn0053434 5SrRNA:CR33434 5SrRNA:CR33434 http://flybase.net/reports/FBgn0053434.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33434 CR33434 16-Dec-15 2015_12 FBgn0259624 B0621 http://flybase.net/reports/FBgn0259624.html gene 16-Dec-15 2015_12 visible wing FBgn0083270 E(smoDN)2640 Enhancer of smoDN 2640 http://flybase.net/reports/FBgn0083270.html gene 16-Dec-15 2015_12 FBgn0033935 Sin1 SAPK-interacting protein 1 http://flybase.net/reports/FBgn0033935.html protein_coding_gene "0048813=dendrite morphogenesis, 0001932=regulation of protein phosphorylation, 0051124=synaptic growth at neuromuscular junction" 0031932=TORC2 complex "stress-activated map kinase-interacting protein 1, dSin1, Stress-activated protein kinase [SAPK]-interacting protein, CG10105, sin1" "IPR008828=Stress-activated map kinase interacting 1, IPR031313=SAPK-interacting protein 1, Pleckstrin-homology domain" CG10105 16-Dec-15 2015_12 ENSDARG00000025835 WBGene00013261(sinh-1) ENSXETG00000000505(MAPKAP1) ENSMUSG00000038696(Mapkap1) ENSG00000119487(MAPKAP1) "viable,fertile,neuroanatomy defective,cell autonomous,somatic clone,small body" "class IV dendritic arborizing neuron,cell autonomous,somatic clone,dendrite | cell autonomous | somatic clone,ventral multidendritic neuron vdaB,abdominal anterior ventral multidendritic neuron vdaa,dorsal multidendritic neuron ddaC,embryonic/larval neuromuscular junction,wing" FBgn0051992 gw gawky http://flybase.net/reports/FBgn0051992.html "FBgn0027730, FBgn0039917, FBgn0039918" protein_coding_gene "0000166=nucleotide binding, 0005515=protein binding, 0003676=nucleic acid binding" "0001700=embryonic development via the syncytial blastoderm, 0035195=gene silencing by miRNA, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0032880=regulation of protein localization, 0006402=mRNA catabolic process, 0045475=locomotor rhythm" 0000932=cytoplasmic mRNA processing body "GW, GW182, GQ182, Gw, anon-EST:Posey205, Gawky, dGW182, CG11484, CG31992, CG9905, Gawki, gw182" "IPR000504=RNA recognition motif domain, IPR009060=UBA-like, IPR019486=Argonaute hook domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR026805=GW182 M domain, IPR015940=Ubiquitin-associated domain" CG31992 16-Dec-15 2015_12 "ENSXETG00000019470(),ENSXETG00000006327()" "ENSMUSG00000025571(Tnrc6c),ENSMUSG00000052707(Tnrc6a),ENSMUSG00000047888(Tnrc6b)" "ENSG00000078687(TNRC6C),ENSG00000090905(TNRC6A),ENSG00000100354(TNRC6B)" "viable,locomotor rhythm defective,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17135 IK 0.665496524 2.6419268 0.618447345 -1.189217022 1.748463007 1.393845439 FBgn0260108 2L3047 http://flybase.net/reports/FBgn0260108.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0085302 CG34273 http://flybase.net/reports/FBgn0085302.html protein_coding_gene CG34273 16-Dec-15 2015_12 FBgn0050099 CG30099 http://flybase.net/reports/FBgn0050099.html FBgn0034107 protein_coding_gene CG7750 CG30099 16-Dec-15 2015_12 viable FBgn0032477 CG5287 http://flybase.net/reports/FBgn0032477.html protein_coding_gene "0008963=phospho-N-acetylmuramoyl-pentapeptide-transferase activity, 0003975=UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity" 0016021=integral component of membrane dAlg7 "IPR000715=Glycosyl transferase, family 4" CG5287 16-Dec-15 2015_12 ENSDARG00000061061(dpagt1) YBR243C(ALG7) WBGene00013362(Y60A3A.14) ENSXETG00000021574(DPAGT1) ENSMUSG00000032123(Dpagt1) ENSG00000172269(DPAGT1) FBgn0015405 l(1)11Fc lethal (1) 11Fc http://flybase.net/reports/FBgn0015405.html gene 16-Dec-15 2015_12 "lethal,semidominant,cold sensitive" FBgn0038058 CG5608 http://flybase.net/reports/FBgn0038058.html protein_coding_gene "0043550=regulation of lipid kinase activity, 0046331=lateral inhibition" 0070772=PAS complex "IPR021841=Vacuolar protein 14 C-terminal Fig4-binding domain, IPR011989=Armadillo-like helical, IPR026825=Vacuole morphology and inheritance protein 14, IPR016024=Armadillo-type fold" CG5608 16-Dec-15 2015_12 ENSDARG00000014303(LOC100333014) YLR386W(VAC14) WBGene00010565(K04G2.6) ENSXETG00000015863(VAC14) ENSMUSG00000010936(Vac14) ENSG00000103043(VAC14) "viable,fertile,visible" "chaeta,supernumerary,wing" DRSC15841 K 0.163739503 0.097698181 0.201557391 0.226853992 1.873373894 -0.169285038 FBgn0043069 MESK4 Misexpression suppressor of KSR 4 http://flybase.net/reports/FBgn0043069.html "FBgn0047207, FBgn0051447" protein_coding_gene 0046579=positive regulation of Ras protein signal transduction "CG31447, BcDNA:LD15753" CG31447 16-Dec-15 2015_12 viable FBgn0053283 CR33283 http://flybase.net/reports/FBgn0053283.html pseudogene_attribute CG33283 CR33283 16-Dec-15 2015_12 FBgn0029903 pod1 pod1 http://flybase.net/reports/FBgn0029903.html "FBgn0046251, FBgn0047221" protein_coding_gene "0051015=actin filament binding, 0008017=microtubule binding, 0030674=protein binding, bridging, 0003779=actin binding" "0030036=actin cytoskeleton organization, 0097113=alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering, 0007411=axon guidance, 0031532=actin cytoskeleton reorganization" "0005794=Golgi apparatus, 0005884=actin filament, 0005881=cytoplasmic microtubule, 0031594=neuromuscular junction, 0030426=growth cone, 0015629=actin cytoskeleton" "BcDNA:LD08951, Pod1, dmPod, coronin, BEST:LD37601, POD-1/coronin, Dpod1, POD-1, CG4532, pod-1" "IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat, IPR015048=Domain of unknown function DUF1899, IPR027331=Coronin 7, IPR015505=Coronin, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG4532 16-Dec-15 2015_12 WBGene00004075(pod-1) ENSMUSG00000039637(Coro7) ENSG00000103426(CORO7) "viable,fertile,cell shape defective" "intersegmental nerve,segmental nerve,ventral nerve cord,longitudinal connective,commissure" FBgn0032075 Tsp29Fb Tetraspanin 29Fb http://flybase.net/reports/FBgn0032075.html FBgn0026295 protein_coding_gene 0016021=integral component of membrane "CG9496, Dm.Tsp29Fb, anon-EST:ParkEST130" "IPR000301=Tetraspanin, IPR000048=IQ motif, EF-hand binding site, IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG9496 16-Dec-15 2015_12 "ENSXETG00000008591(tspan7),ENSXETG00000007608(tspan6)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002137 l(2)K234 lethal (2) K234 http://flybase.net/reports/FBgn0002137.html gene 16-Dec-15 2015_12 lethal FBgn0033872 CG6329 http://flybase.net/reports/FBgn0033872.html protein_coding_gene CG6329 16-Dec-15 2015_12 "WBGene00019663(K11H12.7),WBGene00019662(K11H12.6)" viable FBgn0011949 tRNA:R:12Eb transfer RNA:arg:12Eb http://flybase.net/reports/FBgn0011949.html "FBgn0011947, FBgn0052620, FBgn0060081" tRNA_gene 0033431=CGA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:R:TCG:AE002593-c, chrX.trna9-ArgTCG, tRNA:arg12Eb, tRNA-Arg, AE002593.trna5-ArgTCG, tRNA[arg], transfer RNA:arg1, tRNA:R1, tRNA:arg1, CR32620" CR32620 16-Dec-15 2015_12 FBgn0014935 anon-92Ea anon-92Ea http://flybase.net/reports/FBgn0014935.html gene adm124B10 16-Dec-15 2015_12 FBgn0051355 CG31355 http://flybase.net/reports/FBgn0051355.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004425 LysB Lysozyme B http://flybase.net/reports/FBgn0004425.html FBgn0002575 protein_coding_gene 0003796=lysozyme activity 0019730=antimicrobial humoral response "Lyzozyme B, lysB, CG1179, Lys B" "IPR019799=Glycoside hydrolase, family 22, conserved site, IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain" CG1179 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) " adult stage , larval stage && adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0002260 l(3)68Fe lethal (3) 68Fe http://flybase.net/reports/FBgn0002260.html gene "rsg22, l(3)rsg22, rose-gespleten region interval 22" 16-Dec-15 2015_12 lethal FBgn0003648 Su(z)7 Suppressor of zeste 7 http://flybase.net/reports/FBgn0003648.html gene 16-Dec-15 2015_12 "viable,reduced" FBgn0267411 CG45764 http://flybase.net/reports/FBgn0267411.html protein_coding_gene CG45764 16-Dec-15 2015_12 FBgn0032624 CG6304 http://flybase.net/reports/FBgn0032624.html FBgn0044621 protein_coding_gene anon-WO0140519.248 "IPR009818=Ataxin-2, C-terminal" CG6304 16-Dec-15 2015_12 FBgn0085831 CR42201 http://flybase.net/reports/FBgn0085831.html FBan0042201 pseudogene_attribute CR42201 16-Dec-15 2015_12 FBgn0260317 GSd225 http://flybase.net/reports/FBgn0260317.html gene 16-Dec-15 2015_12 lethal FBgn0001626 l(1)dn3 lethal (1) discs normal 3 http://flybase.net/reports/FBgn0001626.html gene l(1)d.norm.-3 16-Dec-15 2015_12 lethal FBgn0054021 CG34021 http://flybase.net/reports/FBgn0054021.html FBgn0082862 protein_coding_gene "BP1044, unnamed" CG34021 16-Dec-15 2015_12 FBgn0002330 l(3)87Ab lethal (3) 87Ab http://flybase.net/reports/FBgn0002330.html gene "ck9, l(3)ck9" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" FBgn0015889 anon-75Ca anon-75Ca http://flybase.net/reports/FBgn0015889.html gene 16-Dec-15 2015_12 FBgn0032086 CG17906 http://flybase.net/reports/FBgn0032086.html protein_coding_gene CG17906 16-Dec-15 2015_12 viable FBgn0265603 AP-2ë_::stnB http://flybase.net/reports/FBgn0265603.html engineered_fusion_gene "STNB-AP50, STNB-mu2" 16-Dec-15 2015_12 FBgn0014351 ms(2)HB54 ms(2)HB54 http://flybase.net/reports/FBgn0014351.html gene 16-Dec-15 2015_12 FBgn0023063 l(1)2Dj lethal (1) 2Dj http://flybase.net/reports/FBgn0023063.html gene "B3/52.19, 800D22, 800F24" 16-Dec-15 2015_12 "lethal,recessive" FBgn0028575 pp20 pp20 http://flybase.net/reports/FBgn0028575.html gene 16-Dec-15 2015_12 FBgn0035768 CG14834 http://flybase.net/reports/FBgn0035768.html protein_coding_gene CT34650 CG14834 16-Dec-15 2015_12 viable FBgn0065441 l(2)SH1458 lethal (2) SH1458 http://flybase.net/reports/FBgn0065441.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011377 l(3)j5B2 lethal (3) j5B2 http://flybase.net/reports/FBgn0011377.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0043991 Su(rst)D63 Su(rst)D63 http://flybase.net/reports/FBgn0043991.html gene 0001745=compound eye morphogenesis D63 16-Dec-15 2015_12 FBgn0022740 HLH54F HLH54F http://flybase.net/reports/FBgn0022740.html FBgn0020923 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0046982=protein heterodimerization activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007522=visceral muscle development" 0005634=nucleus "bHLH54F, bHLHa9, CG5005, HLH102C, HLH54F-Dm" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG5005 16-Dec-15 2015_12 ENSDARG00000055294 embryonic stage " somatic mesoderm | restricted

, visceral mesoderm | precursor

, visceral mesoderm

" "partially lethal - majority die,increased cell death,lethal,viable,visible" "longitudinal muscle,longitudinal visceral muscle primordium,longitudinal visceral muscle fiber,midgut muscle,cardioblast,embryonic somatic muscle,mesothoracic tergum" FBgn0051158 Efa6 Exchange factor for Arf 6 ortholog (H. sapiens) http://flybase.net/reports/FBgn0051158.html "FBgn0038990, FBgn0038991" protein_coding_gene "0005086=ARF guanyl-nucleotide exchange factor activity, 0005543=phospholipid binding" "0016192=vesicle-mediated transport, 0030182=neuron differentiation, 0032012=regulation of ARF protein signal transduction" "0005802=trans-Golgi network, 0005912=adherens junction" "CG18185, dEfa6, CG31158, Efa6 pleckstrin and Sec7 domain containing, dPsd, EFA6, CG6941" "IPR001849=Pleckstrin homology domain, IPR001478=PDZ domain, IPR023394=Sec7 domain, alpha orthogonal bundle, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000904=Sec7 domain, IPR001605=Pleckstrin homology domain, spectrin-type" CG31158 16-Dec-15 2015_12 WBGene00013223(efa-6) "ENSG00000059915(PSD),ENSG00000146005(PSD2),ENSG00000156011(PSD3)" "viable,fertile" FBgn0033592 CG13215 http://flybase.net/reports/FBgn0033592.html protein_coding_gene CG13215 16-Dec-15 2015_12 viable DRSC06337 E -0.22054764 0.872038881 1.702989349 0.66404377 -0.096001721 -0.428687673 FBgn0030805 wus wurst http://flybase.net/reports/FBgn0030805.html protein_coding_gene "0035002=liquid clearance, open tracheal system, 0035159=regulation of tube length, open tracheal system, 0030198=extracellular matrix organization, 0006897=endocytosis, 0007424=open tracheal system development" "0005769=early endosome, 0005886=plasma membrane, 0031410=cytoplasmic vesicle" "CG9089, Wurst, l(1)G0162" "IPR001623=DnaJ domain, IPR007829=TM2 domain" CG9089 16-Dec-15 2015_12 ENSDARG00000037067(si:dkey-166n8.8) ENSXETG00000011192(DNAJC22) ENSMUSG00000038009(Dnajc22) ENSG00000178401(DNAJC22) "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" "embryonic/larval tracheal system,temperature conditional,presumptive embryonic/larval tracheal system,apical plasma membrane & embryonic tracheal system" FBgn0030717 CG8931 http://flybase.net/reports/FBgn0030717.html protein_coding_gene "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG8931 16-Dec-15 2015_12 ENSDARG00000035181(slc25a46) WBGene00012740(Y40B1B.8) ENSXETG00000021256(TEgg014d12.1) ENSMUSG00000024259(Slc25a46) ENSG00000164209(SLC25A46) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0052670 Rab9Fb Rab at 9Fb http://flybase.net/reports/FBgn0052670.html FBgn0030253 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport" 0031982=vesicle "CG2532, CG32670, Rab GTPase 9Fb, DmRabX3, RabX3" "IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG32670 16-Dec-15 2015_12 FBgn0267022 CR45466 http://flybase.net/reports/FBgn0267022.html non_protein_coding_gene CR45466 16-Dec-15 2015_12 FBgn0051477 ATPsynëµL "ATP synthase, ëµ subunit-like" http://flybase.net/reports/FBgn0051477.html FBgn0040541 protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism, 0046961=proton-transporting ATPase activity, rotational mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism" "0015992=proton transport, 0015986=ATP synthesis coupled proton transport" "0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), 0005753=mitochondrial proton-transporting ATP synthase complex" "ATPE, CG31477, ATP synthase epsilon chain, ATP synthase Epsilon chain, CG12810" "IPR006721=ATPase, F1 complex, epsilon subunit, mitochondrial" CG31477 16-Dec-15 2015_12 YPL271W(ATP15) "WBGene00022582(ZC262.5),WBGene00017982(F32D1.2)" ENSMUSG00000016252(Atp5e) "ENSG00000124172(ATP5E),ENSG00000180389" "viable,visible" trichogen cell DRSC14548 I 0.814122734 -2.043220409 -0.492273682 -1.105919192 0.666402913 1.466715498 FBgn0002495 l(3)SG55 lethal (3) SG55 http://flybase.net/reports/FBgn0002495.html gene l(3)L36 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0038775 CG17199 http://flybase.net/reports/FBgn0038775.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR003767=Malate/L-lactate dehydrogenase CG17199 16-Dec-15 2015_12 ENSXETG00000012341() viable FBgn0000923 fs(1)ne10 female sterile (1) no eggs 10 http://flybase.net/reports/FBgn0000923.html gene "fs(1)ne[10], ne10" 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0005724 l(1)TK134 lethal (1) TK134 http://flybase.net/reports/FBgn0005724.html gene l134 16-Dec-15 2015_12 "lethal,recessive" FBgn0260369 GSd205 http://flybase.net/reports/FBgn0260369.html gene 16-Dec-15 2015_12 lethal FBgn0031412 CG16995 http://flybase.net/reports/FBgn0031412.html protein_coding_gene 0032504=multicellular organism reproduction 0005576=extracellular region "IPR018244=Allergen V5/Tpx-1-related, conserved site, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG16995 16-Dec-15 2015_12 ENSDARG00000067652 WBGene00008604(F09B9.5) viable FBgn0266352 CR45001 http://flybase.net/reports/FBgn0266352.html non_protein_coding_gene CR45001 16-Dec-15 2015_12 FBgn0085574 CG41248 http://flybase.net/reports/FBgn0085574.html FBan0041248 protein_coding_gene 16-Dec-15 2015_12 FBgn0060472 l(3)S112014 lethal (3) S112014 http://flybase.net/reports/FBgn0060472.html gene 1120/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0261267 CG42615 http://flybase.net/reports/FBgn0261267.html "FBan0031829, FBgn0051829, FBgn0001980" protein_coding_gene gft CG42615 16-Dec-15 2015_12 FBgn0060869 l(3)S047208 lethal (3) S047208 http://flybase.net/reports/FBgn0060869.html gene 0472/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267546 CR45886 http://flybase.net/reports/FBgn0267546.html non_protein_coding_gene Mgn1717 CR45886 16-Dec-15 2015_12 FBgn0039215 CG6695 http://flybase.net/reports/FBgn0039215.html protein_coding_gene 0003729=mRNA binding IPR019147=Suppressor of white apricot N-terminal domain CG6695 16-Dec-15 2015_12 ENSDARG00000061742(si:dkey-7l12.4) WBGene00009200(F28C1.1) ENSXETG00000019073(SFRS16) ENSMUSG00000061028(Srsf16) ENSG00000104859(CLASRP) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052804 CG32804 http://flybase.net/reports/FBgn0052804.html protein_coding_gene 16-Dec-15 2015_12 DRSC21314 I 0.926660174 -1.842050949 0.210266771 -0.020597241 0.431697099 0.079495767 FBgn0052248 CG32248 http://flybase.net/reports/FBgn0052248.html protein_coding_gene CG32248 16-Dec-15 2015_12 "viable,fertile" FBgn0264944 CR44113 http://flybase.net/reports/FBgn0264944.html non_protein_coding_gene CR44113 16-Dec-15 2015_12 FBgn0065619 l(2)SH0806 lethal (2) SH0806 http://flybase.net/reports/FBgn0065619.html gene l(2)SH2 0806 16-Dec-15 2015_12 "lethal,recessive" FBgn0260230 CG42504 http://flybase.net/reports/FBgn0260230.html protein_coding_gene CG42504 16-Dec-15 2015_12 FBgn0003047 pcv posterior crossvein http://flybase.net/reports/FBgn0003047.html gene 16-Dec-15 2015_12 visible wing FBgn0264414 FCE-G http://flybase.net/reports/FBgn0264414.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0039223 CG5805 http://flybase.net/reports/FBgn0039223.html protein_coding_gene 0022857=transmembrane transporter activity "0006839=mitochondrial transport, 0055085=transmembrane transport" 0031966=mitochondrial membrane "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein" CG5805 16-Dec-15 2015_12 "ENSDARG00000045927(slc25a44a),ENSDARG00000035905(slc25a44b)" "WBGene00008767(F13G3.7),WBGene00012786(Y43C5B.3)" ENSXETG00000002608(BC080980.1) ENSMUSG00000050144(Slc25a44) ENSG00000160785(SLC25A44) viable DRSC15878 E -0.347565075 -0.328281302 -1.978301092 0.295757719 0.179944278 -0.057406919 FBgn0263030 CG43325 http://flybase.net/reports/FBgn0263030.html "FBgn0034757, FBan0030217, FBgn0050217" protein_coding_gene "CG30217, CG13514" CG43325 16-Dec-15 2015_12 FBgn0003096 Pearl Pearl http://flybase.net/reports/FBgn0003096.html gene Pl 16-Dec-15 2015_12 "viable,male fertile,reduced,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heat sensitive,wing vein,eye,wing margin,macrochaeta,imaginal disc" FBgn0032322 CG16743 http://flybase.net/reports/FBgn0032322.html FBgn0062953 protein_coding_gene BcDNA:RH23514 CG16743 16-Dec-15 2015_12 FBgn0029754 CG15930 http://flybase.net/reports/FBgn0029754.html protein_coding_gene IPR002999=Tudor domain CG15930 16-Dec-15 2015_12 viable FBgn0065248 l(2)SH2136 lethal (2) SH2136 http://flybase.net/reports/FBgn0065248.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004039 yea5 yeast 5 http://flybase.net/reports/FBgn0004039.html gene 16-Dec-15 2015_12 FBgn0031836 CG11050 http://flybase.net/reports/FBgn0031836.html FBgn0063152 protein_coding_gene BcDNA:LD22339 "IPR003607=HD/PDEase domain, IPR006674=HD domain" CG11050 16-Dec-15 2015_12 ENSG00000111906(HDDC2) viable FBgn0001713 l(1)ESHS34 lethal (1) ESHS34 http://flybase.net/reports/FBgn0001713.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267708 CR46041 http://flybase.net/reports/FBgn0267708.html non_protein_coding_gene CR46041 16-Dec-15 2015_12 FBgn0036751 Adgf-B Adenosine deaminase-related growth factor B http://flybase.net/reports/FBgn0036751.html protein_coding_gene "0004000=adenosine deaminase activity, 0008083=growth factor activity" "0046103=inosine biosynthetic process, 0043103=hypoxanthine salvage, 0008283=cell proliferation, 0006154=adenosine catabolic process" "0005829=cytosol, 0005615=extracellular space" "CG5998, ADGF-B, adgfb, AdgfB" "IPR001365=Adenosine/AMP deaminase domain, IPR013659=Adenosine/AMP deaminase N-terminal, IPR006331=Adenosine deaminase-related growth factor" CG5998 16-Dec-15 2015_12 "ENSDARG00000051744,ENSDARG00000051746(cecr1a),ENSDARG00000015623(cecr1b)" ENSXETG00000000874(CECR1) ENSG00000093072(CECR1) viable DRSC24118 K -0.369158908 -0.498485012 0.609054545 -0.203045716 1.555637884 0.143069404 FBgn0026266 bae batone http://flybase.net/reports/FBgn0026266.html gene "0060232=delamination, 0001837=epithelial to mesenchymal transition, 0007472=wing disc morphogenesis, 0048526=imaginal disc-derived wing expansion" baetone 16-Dec-15 2015_12 "viable,fertile,visible,semidominant" "wing,cell non-autonomous" FBgn0044066 GT49-2-4 GT49-2-4 http://flybase.net/reports/FBgn0044066.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0041000 CG15476 http://flybase.net/reports/FBgn0041000.html protein_coding_gene 38D.5 16-Dec-15 2015_12 DRSC02487 IEK 1.516561193 0.629525125 2.00835376 -3.06981675 0.42644284 1.605097904 FBgn0043874 nad1 nurse cell apoptosis defective-1 http://flybase.net/reports/FBgn0043874.html gene 0045476=nurse cell apoptotic process nad-1 16-Dec-15 2015_12 FBgn0036671 CG9951 http://flybase.net/reports/FBgn0036671.html protein_coding_gene IPR008530=Protein of unknown function DUF812 CG9951 16-Dec-15 2015_12 ENSDARG00000052379(zgc:114058) WBGene00019959(R08E3.3) ENSMUSG00000031143(Ccdc22) ENSG00000101997(CCDC22) viable FBgn0031842 Tango1 Transport and Golgi organization 1 http://flybase.net/reports/FBgn0031842.html protein_coding_gene "0051047=positive regulation of secretion, 0009306=protein secretion, 0007030=Golgi organization, 0033363=secretory granule organization" "0005794=Golgi apparatus, 0000137=Golgi cis cisterna, 0012505=endomembrane system, 0070971=endoplasmic reticulum exit site" "CG11098, transport and Golgi organisation 1, TANGO1" IPR001452=SH3 domain CG11098 16-Dec-15 2015_12 ENSMUSG00000056050 ENSG00000154305(MIA3) "lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval proventriculus outer layer,secretory granuleunspecified" DRSC27972 K -0.490480529 -0.238042993 -0.191774262 -0.468782202 -0.216851909 2.287234091 FBgn0034030 CG8192 http://flybase.net/reports/FBgn0034030.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG8192 16-Dec-15 2015_12 viable DRSC07101 IE -1.118523549 -2.663406072 -0.335582856 -2.05762204 -0.293378602 -0.556071573 FBgn0031288 CG13949 http://flybase.net/reports/FBgn0031288.html FBgn0063756 protein_coding_gene BcDNA:AT06839 CG13949 16-Dec-15 2015_12 viable DRSC00367 K 0.139036982 -0.592194996 -0.038950647 0.52576729 1.932551119 -0.115599557 FBgn0267461 CR45811 http://flybase.net/reports/FBgn0267461.html non_protein_coding_gene CR45811 16-Dec-15 2015_12 FBgn0020442 Eric Ecdysone receptor interacting co-repressor http://flybase.net/reports/FBgn0020442.html gene 0003714=transcription corepressor activity "0045892=negative regulation of transcription, DNA-templated" 16-Dec-15 2015_12 FBgn0038666 Smu1 SMU1 ortholog http://flybase.net/reports/FBgn0038666.html protein_coding_gene "0072553=terminal button organization, 0000398=mRNA splicing, via spliceosome, 0007274=neuromuscular synaptic transmission, 0007528=neuromuscular junction development" "0005634=nucleus, 0071011=precatalytic spliceosome, 0005737=cytoplasm, 0071013=catalytic step 2 spliceosome" "CG5451, dsmu1" "IPR006595=CTLH, C-terminal LisH motif, IPR001680=WD40 repeat, IPR006594=LIS1 homology motif, IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG5451 16-Dec-15 2015_12 ENSDARG00000002538(smu1) WBGene00004895(smu-1) ENSXETG00000024145(smu1) ENSMUSG00000028409(Smu1) ENSG00000122692(SMU1) "neuroanatomy defective,neurophysiology defective,viable" NMJ bouton FBgn0267471 CR45821 http://flybase.net/reports/FBgn0267471.html non_protein_coding_gene CR45821 16-Dec-15 2015_12 FBgn0001591 l(1)carot8 lethal (1) carot8 http://flybase.net/reports/FBgn0001591.html gene 16-Dec-15 2015_12 lethal FBgn0001726 l(1)ESHS47 lethal (1) ESHS47 http://flybase.net/reports/FBgn0001726.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020595 anon-57Cb anon-57Cb http://flybase.net/reports/FBgn0020595.html gene unnamed 16-Dec-15 2015_12 FBgn0039673 CG7568 http://flybase.net/reports/FBgn0039673.html protein_coding_gene "IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain" CG7568 16-Dec-15 2015_12 ENSDARG00000021462(wdr69) "ENSXETG00000026821(wdr69),ENSXETG00000012678()" ENSMUSG00000053161(Wdr69) ENSG00000123977(WDR69) viable FBgn0040324 Ephrin Ephrin http://flybase.net/reports/FBgn0040324.html FBgn0039910 protein_coding_gene 0046875=ephrin receptor binding "0016319=mushroom body development, 0007422=peripheral nervous system development, 0035011=melanotic encapsulation of foreign target, 0007411=axon guidance" 0005887=integral component of plasma membrane "ephrin, lincRNA.922, Dephrin, CG1862" "IPR031328=Ephrin, IPR001799=Ephrin receptor-binding domain, IPR008972=Cupredoxin" CG1862 16-Dec-15 2015_12 "ENSDARG00000030326(efna1a),ENSDARG00000018787(LOC100333317),ENSDARG00000032485(efna3b),ENSDARG00000014675(efna3a),ENSDARG00000031372(efna2),ENSDARG00000057223(efna5a)" WBGene00001165(efn-4) " embryonic stage | stage 4-5 , embryonic stage | stage 13 , embryonic stage | late , embryonic stage | gastrula , " "

, ventral ectoderm && embryonic somatic muscle | ventral && embryonic central nervous system | restricted

, central nervous system | restricted

, mesoderm | restricted

, cell

" "neuroanatomy defective,somatic clone,viable,recessive,fertile,immune response defective,visible" "adult antennal lobe projection neuron,somatic clone,mushroom body alpha-lobe,presumptive embryonic/larval central nervous system,commissure,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,eye,medulla neuropil,lobula,longitudinal connective,embryonic/larval neuron" FBgn0266215 CR44910 http://flybase.net/reports/FBgn0266215.html non_protein_coding_gene CR44910 16-Dec-15 2015_12 FBgn0020344 anon-51Ba anon-51Ba http://flybase.net/reports/FBgn0020344.html gene 514 16-Dec-15 2015_12 FBgn0021938 l(2)k10816 lethal (2) k10816 http://flybase.net/reports/FBgn0021938.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0031041 CG12788 http://flybase.net/reports/FBgn0031041.html "FBgn0053066, FBtr0074765, FBpp0074534, FBtr0074766, FBpp0074535, FBtr0074767, FBpp0074536" protein_coding_gene "PSTK, CG33066, Dromel_CG12788_CG17767_FBtr0074_tim9b_mORF" "IPR013641=Protein KTI12/L-seryl-tRNA(Sec) kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12788 16-Dec-15 2015_12 WBGene00013041(pstk-1) ENSMUSG00000063179(Pstk) ENSG00000179988(PSTK) FBgn0015320 Ubc2 Ubiquitin conjugating enzyme 2 http://flybase.net/reports/FBgn0015320.html FBgn0021893 protein_coding_gene 0004842=ubiquitin-protein transferase activity "0019915=lipid storage, 0000209=protein polyubiquitination" "UbcD2, ubiquitin conjugating enzyme 2, ubcD2, l(2)k13206, CG6720" "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG6720 16-Dec-15 2015_12 "ENSDARG00000012244(ube2e3),ENSDARG00000009375,ENSDARG00000034670(zgc:92467)" "ENSXETG00000026975(ube2e1),ENSXETG00000025043(ube2e3)" "ENSMUSG00000021774(Ube2e1),ENSMUSG00000058317(Ube2e2),ENSMUSG00000027011(Ube2e3)" "ENSG00000182247(UBE2E2),ENSG00000170142(UBE2E1)" "lethal,recessive,neuroanatomy defective,somatic clone,visible,viable" "neuroblast,somatic clone,macrochaeta,scutellar bristle,tormogen cell,trichogen cell,ectopic,mesothoracic tergum" FBgn0025941 anon-89Bb anon-89Bb http://flybase.net/reports/FBgn0025941.html gene 89B-ov3.5 16-Dec-15 2015_12 adult stage ovary

FBgn0062624 Mod(var)1126 Mod(var)1126 http://flybase.net/reports/FBgn0062624.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1126 16-Dec-15 2015_12 "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0052196 CG32196 http://flybase.net/reports/FBgn0052196.html protein_coding_gene 0003839=gamma-glutamylcyclotransferase activity 0006750=glutathione biosynthetic process "IPR013024=Butirosin biosynthesis, BtrG-like, IPR017939=Gamma-glutamylcyclotransferase" CG32196 16-Dec-15 2015_12 ENSDARG00000005085(ggct) WBGene00016629(C44B7.7) ENSXETG00000022014(TEgg096f01.1) ENSMUSG00000002797(Ggct) ENSG00000006625(GGCT) FBgn0004598 Fur2 Furin 2 http://flybase.net/reports/FBgn0004598.html FBgn0042227 protein_coding_gene 0004252=serine-type endopeptidase activity "0016485=protein processing, 0051048=negative regulation of secretion, 0006508=proteolysis" 0005886=plasma membrane "Dfurin2, furin2, furin 2, Furin-like protease, 154521_at, Dfur2, Furin, fur2, DMH#11, CG18734, furin, CG4235, FUR2" "IPR002884=Proprotein convertase, P, IPR000209=Peptidase S8/S53 domain, IPR009020=Proteinase inhibitor, propeptide, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR006212=Furin-like repeat, IPR022398=Peptidase S8, subtilisin, His-active site, IPR023827=Peptidase S8, subtilisin, Asp-active site, IPR008979=Galactose-binding domain-like, IPR015500=Peptidase S8, subtilisin-related, IPR000742=EGF-like domain, IPR023828=Peptidase S8, subtilisin, Ser-active site" CG18734 16-Dec-15 2015_12 ENSDARG00000067537(pcsk5a) ENSXETG00000006663(PCSK6) ENSMUSG00000024713(Pcsk5) ENSG00000140479(PCSK6) viable FBgn0038210 CG3199 http://flybase.net/reports/FBgn0038210.html protein_coding_gene CG3199 16-Dec-15 2015_12 viable FBgn0265252 CR44266 http://flybase.net/reports/FBgn0265252.html non_protein_coding_gene CR44266 16-Dec-15 2015_12 FBgn0064165 l(3)Eq1 lethal (3) Eq1 http://flybase.net/reports/FBgn0064165.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024887 kin17 kin17 http://flybase.net/reports/FBgn0024887.html FBgn0036976 protein_coding_gene 0003676=nucleic acid binding "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome CG5649 "IPR015880=Zinc finger, C2H2-like, IPR019447=DNA/RNA-binding protein Kin17, conserved domain" CG5649 16-Dec-15 2015_12 ENSDARG00000045515(kin) WBGene00013128(Y52B11A.9) ENSMUSG00000037262(Kin) ENSG00000151657(KIN) viable FBgn0030729 CG12507 http://flybase.net/reports/FBgn0030729.html protein_coding_gene CG12507 16-Dec-15 2015_12 viable FBgn0060540 l(3)S100108a lethal (3) S100108a http://flybase.net/reports/FBgn0060540.html gene 1001/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0051728 CG31728 http://flybase.net/reports/FBgn0051728.html FBgn0032496 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP36, CG16821, c-SP36" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG31728 16-Dec-15 2015_12 FBgn0024858 l(3)96Bd lethal (3) 96Bd http://flybase.net/reports/FBgn0024858.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067100 H47 H47 http://flybase.net/reports/FBgn0067100.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal" "chaeta,ommatidium,pigment cell" FBgn0060795 l(3)S058407 lethal (3) S058407 http://flybase.net/reports/FBgn0060795.html gene 0584/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0267681 CR46017 http://flybase.net/reports/FBgn0267681.html non_protein_coding_gene CR46017 16-Dec-15 2015_12 FBgn0005439 l(1)v129 lethal (1) v129 http://flybase.net/reports/FBgn0005439.html gene l(1)129 16-Dec-15 2015_12 FBgn0263102 psq pipsqueak http://flybase.net/reports/FBgn0263102.html "FBgn0069087, FBgn0004399, FBgn0012047, FBgn0045853" protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0031208=POZ domain binding, 0042803=protein homodimerization activity" "0042048=olfactory behavior, 0007315=pole plasm assembly, 0031935=regulation of chromatin silencing, 0009880=embryonic pattern specification, 0006342=chromatin silencing, 0007476=imaginal disc-derived wing morphogenesis, 0016458=gene silencing, 0008595=anterior/posterior axis specification, embryo" "0031519=PcG protein complex, 0005634=nucleus" "PSQ, zep, Piq, BTB-protein-V, zepplin, zeppelin, BTB-V, eyeful, Pipsqueak, rum, Pipsqeak, rumpf, CG2368, pip, BtbV, Peepsqueak, psk, psq-1, Psq" "IPR009057=Homeodomain-like, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR007889=DNA binding HTH domain, Psq-type" CG2368 16-Dec-15 2015_12 ENSXETG00000017921(ZBTB44) " embryonic stage | 0-2 hr , embryonic stage | stage 5-8 , embryonic stage | late , larval stage | third instar , oogenesis stage , embryonic stage | stage 7-8 , embryonic stage | stage 5 " "

dorsal<&>anterior , maxillary segment

, photoreceptor cell R3 && photoreceptor cell R4

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, amnioserosa

, mandibular segment

, morphogenetic furrow | posterior to

, labial segment

,

20-70% egg length | dorsal " " adult stage && oogenesis stage | early , oogenesis stage | stage S10 && adult stage | female , larval stage " " germarium region 2a

, follicle cell

, eye-antennal disc | restricted

, dorsal mesothoracic disc

" FBgn0262903 CR43258 http://flybase.net/reports/FBgn0262903.html non_protein_coding_gene lincRNA.813 CR43258 16-Dec-15 2015_12 FBgn0250753 kra krasavietz http://flybase.net/reports/FBgn0250753.html "FBgn0061514, FBgn0046382, FBgn0010791, FBgn0037346, FBgn0011418" protein_coding_gene "0031369=translation initiation factor binding, 0005515=protein binding, 0043022=ribosome binding" "0051491=positive regulation of filopodium assembly, 0048477=oogenesis, 0007616=long-term memory, 0016199=axon midline choice point recognition, 0048149=behavioral response to ethanol, 0048663=neuron fate commitment, 0017148=negative regulation of translation" "0030175=filopodium, 0043025=neuronal cell body, 0030424=axon, 0044295=axonal growth cone, 0005737=cytoplasm" "elF5C, l(3)03022, eIF-5C, eIf-5c, l(3)j9B6, krasavietz, extra-bases, eukaryotic initiation factor 5C, exba, elf-5C, Krasavietz, ecp, anon-WO0172774.49, lethal (3) j9B6, eIF5c, elF-5C, CG2922, ECP, eiF-5C, extra bases, eIF, eIF-5c, chr3R:1423015..1423173, Decp, Kra, Drosophila eIF5C-containing protein, CT7240, extra bses, Exba, eIF5, kra" "IPR016024=Armadillo-type fold, IPR016021=MIF4G-like domain, IPR003307=W2 domain" CG2922 16-Dec-15 2015_12 "ENSDARG00000010481(bzw1a),ENSDARG00000034961(bzw1b),ENSDARG00000035918(bzw2)" "ENSMUSG00000051223(Bzw1),ENSMUSG00000020547(Bzw2)" "ENSG00000082153(BZW1),ENSG00000136261(BZW2)" DRSC12320 IEK 0.332813796 -3.202455523 -1.511429492 1.449847694 -1.662290281 0.103800187 FBgn0036581 MED10 Mediator complex subunit 10 http://flybase.net/reports/FBgn0036581.html "FBgn0045445, FBgn0062851" protein_coding_gene "0005515=protein binding, 0001104=RNA polymerase II transcription cofactor activity, 0003713=transcription coactivator activity" "0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0007406=negative regulation of neuroblast proliferation" 0016592=mediator complex "med10, CG5057, Med10, BcDNA:SD24044, Nut2, dTRAP15, Mediator, l(3)72Ds, dMED10" "IPR019145=Mediator complex, subunit Med10" CG5057 16-Dec-15 2015_12 "ENSDARG00000067574,ENSDARG00000070623(med10)" YPR168W(NUT2) WBGene00007014(mdt-10) ENSXETG00000026404(TEgg027l06.1) ENSMUSG00000021598(Med10) ENSG00000133398(MED10) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC10474 EK -1.078593002 1.089935008 -2.440556108 -0.179582626 2.873923399 3.684931128 FBgn0039435 TwdlP TweedleP http://flybase.net/reports/FBgn0039435.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix CG14240 IPR004145=Domain of unknown function DUF243 CG14240 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,viable" DRSC14734 I 1.976514686 0.081340687 0.619697568 -0.452202267 0.144693257 0.745605585 FBgn0036131 CG12522 http://flybase.net/reports/FBgn0036131.html protein_coding_gene CG12522 16-Dec-15 2015_12 viable DRSC09088 I 1.932882938 0.456025944 -1.08514863 0.028996724 0.287038533 0.108066761 FBgn0058337 CG40337 http://flybase.net/reports/FBgn0058337.html FBan0040337 protein_coding_gene 16-Dec-15 2015_12 DRSC20701 IE -1.561639011 -0.99108678 -0.683278749 3.12587321 -0.243989747 -0.154654799 FBgn0014075 Ugt UDP-glucose-glycoprotein glucosyltransferase http://flybase.net/reports/FBgn0014075.html "FBgn0046358, FBgn0046359" protein_coding_gene 0003980=UDP-glucose:glycoprotein glucosyltransferase activity 0006486=protein glycosylation "0005783=endoplasmic reticulum, 0005635=nuclear envelope, 0005791=rough endoplasmic reticulum, 0005737=cytoplasm, 0012505=endomembrane system" "UGGT, UGT, anon-WO0172774.73, anon-WO0172774.75, GT, DUGT, CG6850, ugt, UDP-glucose:glycoprotein glucosyltransferase" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR009448=UDP-glucose:Glycoprotein Glucosyltransferase, IPR002495=Glycosyl transferase, family 8" CG6850 16-Dec-15 2015_12 "ENSDARG00000062089,ENSDARG00000054746(zgc:152896)" YOR336W(KRE5) WBGene00018604(F48E3.3) "ENSMUSG00000037470(Uggt1),ENSMUSG00000042104(Uggt2)" "ENSG00000136731(UGGT1),ENSG00000102595(UGGT2)" " embryonic stage--pupal stage , embryonic stage "

ubiquitous " embryonic stage -- adult stage , adult stage && oogenesis stage " oocyte

viable FBgn0039739 RpS28a Ribosomal protein S28a http://flybase.net/reports/FBgn0039739.html protein_coding_gene 0003735=structural constituent of ribosome "0002181=cytoplasmic translation, 0006407=rRNA export from nucleus, 0006412=translation, 0035220=wing disc development" 0022627=cytosolic small ribosomal subunit CG15527 "IPR000289=Ribosomal protein S28e, IPR012340=Nucleic acid-binding, OB-fold, IPR028626=Ribosomal protein S28e conserved site" CG15527 16-Dec-15 2015_12 "YLR264W(RPS28B),YOR167C(RPS28A)" WBGene00004497(rps-28) "ENSMUSG00000067288(Rps28),ENSMUSG00000069188(Gm13192),ENSMUSG00000069196(Gm10263),ENSMUSG00000072576(Gm16417),ENSMUSG00000066407(Gm10161)" viable "wing,macrochaeta,ectopic" FBgn0085461 CG34432 http://flybase.net/reports/FBgn0085461.html "FBgn0039794, FBan0015541" protein_coding_gene CG15541 CG34432 16-Dec-15 2015_12 FBgn0065598 l(2)SH0880 lethal (2) SH0880 http://flybase.net/reports/FBgn0065598.html gene l(2)SH2 0880 16-Dec-15 2015_12 "lethal,recessive" FBgn0260099 2L3443 http://flybase.net/reports/FBgn0260099.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0010425 ëµTry ëµTrypsin http://flybase.net/reports/FBgn0010425.html FBgn0040762 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "Try, DmEpsilonTry, SP88, epsilon, epsilonTrypsin, CG18681, epsilonTry" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG18681 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" viable FBgn0026575 hang hangover http://flybase.net/reports/FBgn0026575.html "FBgn0030750, FBgn0030751, FBgn0052575, FBgn0062484" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "0006979=response to oxidative stress, 0048149=behavioral response to ethanol, 0009408=response to heat" 0005634=nucleus "BcDNA:LD22118, LD22118, BcDNA:GM07804, CG4411, CG32575, CG4416, HANG" "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2" CG32575 16-Dec-15 2015_12 ENSG00000148143(ZNF462) "viable,chemical sensitive,short lived,partially lethal - majority die,visible,lethal,female sterile,female semi-sterile" "wing,trichogen cell" FBgn0037022 CG11396 http://flybase.net/reports/FBgn0037022.html protein_coding_gene "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG11396 16-Dec-15 2015_12 ENSDARG00000060101(zgc:158466) WBGene00016614(C43H6.1) ENSXETG00000006961(ttc15) ENSG00000171853(TTC15) "viable,fertile,visible" trichogen cell FBgn0069143 mcl(3)Z4617 mcl(3)Z4617 http://flybase.net/reports/FBgn0069143.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0065289 l(2)SH2016 lethal (2) SH2016 http://flybase.net/reports/FBgn0065289.html gene l(2)SH2 2016 16-Dec-15 2015_12 "lethal,recessive" FBgn0011595 FTaseë± Farnesyltransferase ë± subunit http://flybase.net/reports/FBgn0011595.html gene 0004660=protein farnesyltransferase activity 0018343=protein farnesylation 0005965=protein farnesyltransferase complex 16-Dec-15 2015_12 FBgn0036415 CG7768 http://flybase.net/reports/FBgn0036415.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding" "IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase" CG7768 16-Dec-15 2015_12 ENSDARG00000009212(ppia) YDR155C(CPR1) "WBGene00000879(cyn-3),WBGene00000883(cyn-7),WBGene00000878(cyn-2),WBGene00000877(cyn-1)" ENSXETG00000018981(ppia) ENSMUSG00000021868(Ppif) ENSG00000108179(PPIF) viable FBgn0002838 ms(3)K81 male sterile (3) K81 http://flybase.net/reports/FBgn0002838.html FBgn0039460 protein_coding_gene 0016233=telomere capping "0000781=chromosome, telomeric region, 0005634=nucleus, 0000794=condensed nuclear chromosome" "ph, K81, paternal-haploid, CG14251, ms(3)97Dg, ms(3)k81, paternal haploid" CG14251 16-Dec-15 2015_12 "mitotic cell cycle defective,paternal effect,lethal,viable,male sterile" chromosome | paternal effect FBgn0039511 CG3330 http://flybase.net/reports/FBgn0039511.html FBgn0044733 protein_coding_gene anon-WO0140519.147 CG3330 16-Dec-15 2015_12 viable FBgn0033454 CG1671 http://flybase.net/reports/FBgn0033454.html protein_coding_gene "0022008=neurogenesis, 0006364=rRNA processing, 0009267=cellular response to starvation" 0032040=small-subunit processome "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR013934=Small-subunit processome, Utp13, IPR020472=G-protein beta WD-40 repeat" CG1671 16-Dec-15 2015_12 YLR222C(UTP13) WBGene00013143(Y53C12B.1) ENSXETG00000007217(TBL3) ENSMUSG00000040688(Tbl3) ENSG00000183751(TBL3) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0035336 CG9004 http://flybase.net/reports/FBgn0035336.html protein_coding_gene 0003723=RNA binding 0022008=neurogenesis 0005730=nucleolus "IPR016021=MIF4G-like domain, IPR016024=Armadillo-type fold, IPR003890=MIF4G-like, type 3, IPR003891=Initiation factor eIF-4 gamma, MA3" CG9004 16-Dec-15 2015_12 ENSDARG00000060027(nom1) YLR336C(SGD1) WBGene00013129(Y52B11A.10) ENSMUSG00000001569(Nom1) ENSG00000146909(NOM1) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0259960 CG42470 http://flybase.net/reports/FBgn0259960.html protein_coding_gene CG42470 16-Dec-15 2015_12 FBgn0033918 CG8531 http://flybase.net/reports/FBgn0033918.html protein_coding_gene "IPR001623=DnaJ domain, IPR024586=DnaJ-like protein C11, C-terminal" CG8531 16-Dec-15 2015_12 "ENSDARG00000011196(dnajc11),ENSDARG00000036280" WBGene00001027(dnj-9) ENSXETG00000011143(DNAJC11) ENSMUSG00000039768(Dnajc11) ENSG00000007923(DNAJC11) "viable,fertile" "wing,posterior compartment" FBgn0262432 mir-8 mir-8 stem loop http://flybase.net/reports/FBgn0262432.html "FBgn0046815, FBgn0082172, FBgn0262281" miRNA_gene "0045805=positive regulation of eclosion, 0007480=imaginal disc-derived leg morphogenesis, 0048095=female pigmentation, 0007528=neuromuscular junction development, 0035195=gene silencing by miRNA, 0040018=positive regulation of multicellular organism growth, 0016055=Wnt signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0021782=glial cell development, 1990255=subsynaptic reticulum organization, 0014019=neuroblast development, 0050768=negative regulation of neurogenesis, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0042065=glial cell growth" "8 mir, miR-8, CR42988, dme-miR-8-3p, CR33562, CR33018, mir-8, dme-mir-8, mir-8*, 8, mir8S, MiR-8, miR8, mir-8S, dme-miR-8" CR42988 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0060491 l(3)S110006b lethal (3) S110006b http://flybase.net/reports/FBgn0060491.html gene 1100/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0051102 CG31102 http://flybase.net/reports/FBgn0051102.html FBgn0039317 protein_coding_gene CG10634 "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG31102 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable DRSC14260 I -0.657362049 7.161830223 0.170485258 0.442561105 -0.065256733 0.448166557 FBgn0063415 l(3)3450-H lethal (3) 3450-H http://flybase.net/reports/FBgn0063415.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053437 5SrRNA:CR33437 5SrRNA:CR33437 http://flybase.net/reports/FBgn0053437.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33437 CR33437 16-Dec-15 2015_12 FBgn0264888 CR44079 http://flybase.net/reports/FBgn0264888.html pseudogene_attribute CR44079 16-Dec-15 2015_12 FBgn0040321 GNBP3 Gram-negative bacteria binding protein 3 http://flybase.net/reports/FBgn0040321.html FBgn0035939 protein_coding_gene "0001530=lipopolysaccharide binding, 0008329=signaling pattern recognition receptor activity, 0052736=beta-glucanase activity, 0001872=(1->3)-beta-D-glucan binding" "0005975=carbohydrate metabolic process, 0009620=response to fungus, 0002758=innate immune response-activating signal transduction, 0045088=regulation of innate immune response, 0032491=detection of molecule of fungal origin" "0009986=cell surface, 0005576=extracellular region" "Gram-negative binding protein 3, gnbp3, CG5008, GNBP, DGNBP-3, Hades, GNBP-3, Gnbp3" "IPR000757=Glycoside hydrolase, family 16, IPR013320=Concanavalin A-like lectin/glucanase domain" CG5008 16-Dec-15 2015_12 "immune response defective,viable" FBgn0001340 l(1)1Bh lethal (1) 1Bh http://flybase.net/reports/FBgn0001340.html gene l(1)PB 16-Dec-15 2015_12 "lethal,polyphasic,lethal - all die before end of pupal stage,recessive,some die during pupal stage,partially lethal - majority die,visible" wing FBgn0034654 CG10306 http://flybase.net/reports/FBgn0034654.html protein_coding_gene "0003743=translation initiation factor activity, 0043022=ribosome binding" 0006446=regulation of translational initiation 0005852=eukaryotic translation initiation factor 3 complex eIF3k "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR016020=Translation initiation factor 3, subunit 12, N-terminal, eukaryotic, IPR009374=Eukaryotic translation initiation factor 3 subunit K, IPR016024=Armadillo-type fold" CG10306 16-Dec-15 2015_12 ENSDARG00000032311 WBGene00001233(eif-3.K) ENSXETG00000024723(eif3s12) ENSMUSG00000053565(Eif3k) ENSG00000178982(EIF3K) FBgn0037110 ORMDL ORMDL http://flybase.net/reports/FBgn0037110.html protein_coding_gene "0005829=cytosol, 0016021=integral component of membrane, 0005789=endoplasmic reticulum membrane" CG14577 IPR007203=ORMDL family CG14577 16-Dec-15 2015_12 "ENSDARG00000025555(zgc:101654),ENSDARG00000014333(ormdl1),ENSDARG00000058022(zgc:136901)" "YGR038W(ORM1),YLR350W(ORM2)" "ENSXETG00000024658(ORMDL2),ENSXETG00000009884(ORMDL1)" "ENSMUSG00000038150(Ormdl3),ENSMUSG00000026097(Ormdl1),ENSMUSG00000025353(Ormdl2)" "ENSG00000172057(ORMDL3),ENSG00000128699(ORMDL1),ENSG00000123353(ORMDL2)" "viable,fertile" FBgn0001646 l(1)dn26 lethal (1) discs normal 26 http://flybase.net/reports/FBgn0001646.html gene l(1)d.norm.-26 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005299 mei-I3 meiotic I3 http://flybase.net/reports/FBgn0005299.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive" "meiosis I,meiosis II" FBgn0003902 Two-b Two bristles http://flybase.net/reports/FBgn0003902.html FBgn0004615 gene 16-Dec-15 2015_12 "lethal,recessive,viable,good" "postvertical bristle,dorsocentral bristle" FBgn0035542 DOR http://flybase.net/reports/FBgn0035542.html protein_coding_gene "0035258=steroid hormone receptor binding, 0030374=ligand-dependent nuclear receptor transcription coactivator activity" "0010506=regulation of autophagy, 0008285=negative regulation of cell proliferation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035076=ecdysone receptor-mediated signaling pathway" 0005634=nucleus "CG11347, DOR, dDOR" "IPR029556=Tumor protein p53-inducible nuclear protein 1, IPR029431=Tumour protein p53-inducible nuclear protein" CG11347 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" "anterior pupal spiracle,salivary gland,autophagic vacuole" FBgn0016010 l(3)63Fd lethal (3) 63Fd http://flybase.net/reports/FBgn0016010.html gene l(3)SH6 16-Dec-15 2015_12 "lethal,recessive" FBgn0010121 l(1)8Ab lethal (1) 8Ab http://flybase.net/reports/FBgn0010121.html gene HF383 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0051162 tRNA:CR31162 transfer RNA:CR31162 http://flybase.net/reports/FBgn0051162.html "FBgn0011968, FBgn0011969, FBgn0011972, FBgn0060056" tRNA_gene "0033446=AGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:S:GCT:AE002708-d, tRNA:S, transfer RNA:ser, tRNA[Ser][[2b]], tRNA:S2b:94A, transfer RNA:ser2b, CR31162, tRNA[[Ser]], AE002708.trna39-SerGCT, tRNA:S2b, transfer RNA:ser2b:94A, tRNA:ser2b:94A, tRNA:ser, chr3R.trna45-SerGCT, tRNA:ser2b" CR31162 16-Dec-15 2015_12 FBgn0027135 l(3)89ABa lethal (3) 89ABa http://flybase.net/reports/FBgn0027135.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0046326 ms(2)38ABa ms(2)38ABa http://flybase.net/reports/FBgn0046326.html gene ms in 38A/B 16-Dec-15 2015_12 FBgn0031170 CG1718 http://flybase.net/reports/FBgn0031170.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR026082=ABC transporter A, ABCA, IPR003593=AAA+ ATPase domain" CG1718 16-Dec-15 2015_12 ENSDARG00000013500(abca2) "YIL013C(PDR11),YOR011W(AUS1),YNR070W(PDR18),YDR011W(SNQ2),YPL058C(PDR12),YOR328W(PDR10),YOR153W(PDR5),YDR406W(PDR15),YOL075C()" WBGene00000022(abt-4) ENSXETG00000020232(ABCA3) "ENSMUSG00000024130(Abca3),ENSMUSG00000035435(Abca17),ENSMUSG00000054746(Abca15),ENSMUSG00000062017(Abca14),ENSMUSG00000051900(Abca16)" ENSG00000167972(ABCA3) viable DRSC20546 K 0.229437717 0.315420842 0.25940021 0.91173629 -0.208019204 -1.509490163 FBgn0013724 Raf::tor phl::tor http://flybase.net/reports/FBgn0013724.html engineered_fusion_gene "sev-raf, raf, phl::tor, unnamed" 16-Dec-15 2015_12 "visible,dominant" "ommatidium,photoreceptor cell R7,supernumerary,eye,ectopic,cone cell,photoreceptor cell,abdomen,eye disc,somatic clone" FBgn0039489 CG5880 http://flybase.net/reports/FBgn0039489.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005794=Golgi apparatus "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG5880 16-Dec-15 2015_12 ENSDARG00000007808(zdhhc16) WBGene00016620(C43H6.7) ENSXETG00000003436(zdhhc16) ENSMUSG00000025157(Zdhhc16) ENSG00000171307(ZDHHC16) "lethal,partially lethal - majority die,some die during pupal stage" FBgn0266357 CR45005 http://flybase.net/reports/FBgn0266357.html non_protein_coding_gene CR45005 16-Dec-15 2015_12 FBgn0260084 2L3179 http://flybase.net/reports/FBgn0260084.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone,dorsal air sac primordium" FBgn0264987 CR44138 http://flybase.net/reports/FBgn0264987.html non_protein_coding_gene CR44138 16-Dec-15 2015_12 FBgn0024653 l(2)k08307 lethal (2) k08307 http://flybase.net/reports/FBgn0024653.html gene 83/7 16-Dec-15 2015_12 "lethal,recessive" FBgn0032089 Rcd-1r Rcd-1 related http://flybase.net/reports/FBgn0032089.html protein_coding_gene "0007283=spermatogenesis, 0022414=reproductive process" 0005634=nucleus "Zeus, Drcd-1r, Drcd-1 related, CG9573" "IPR007216=Rcd1/Caf40, IPR016024=Armadillo-type fold" CG9573 16-Dec-15 2015_12 YNL288W(CAF40) WBGene00016139(C26E6.3) "male semi-sterile,female fertile,male semi-fertile" testis FBgn0021995 Rs1 Rs1 http://flybase.net/reports/FBgn0021995.html FBgn0028477 protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0003676=nucleic acid binding, 0003724=RNA helicase activity" "0042254=ribosome biogenesis, 0040018=positive regulation of multicellular organism growth" "cg2173, l(2)k09514, BcDNA:GM05306, 153844_at, Drs1, DmRH21, CG2173" "IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650=Helicase, C-terminal" CG2173 16-Dec-15 2015_12 YLL008W(DRS1) WBGene00022148(Y71G12B.8) ENSXETG00000017231(DDX27) ENSMUSG00000017999(Ddx27) ENSG00000124228(DDX27) "lethal,recessive,viable,visible" mesothoracic tergum DRSC05945 E -1.395678537 0.720694061 1.543172694 -0.124592027 -0.063330169 -0.169392667 FBgn0024678 l(1)LefEM3 lethal (1) LefEM3 http://flybase.net/reports/FBgn0024678.html gene EM3 16-Dec-15 2015_12 FBgn0265084 CG44195 http://flybase.net/reports/FBgn0265084.html protein_coding_gene CG44195 16-Dec-15 2015_12 FBgn0267990 CR46257 http://flybase.net/reports/FBgn0267990.html non_protein_coding_gene CR46257 16-Dec-15 2015_12 FBgn0267722 CR46055 http://flybase.net/reports/FBgn0267722.html non_protein_coding_gene CR46055 16-Dec-15 2015_12 FBgn0259919 Csp::nSyb http://flybase.net/reports/FBgn0259919.html engineered_fusion_gene "Csp::n-Syb, Csp::n-syb" 16-Dec-15 2015_12 FBgn0052699 LPCAT Lysophosphatidylcholine acyltransferase http://flybase.net/reports/FBgn0052699.html "FBgn0030138, FBgn0030139, FBgn0040935" protein_coding_gene "0047184=1-acylglycerophosphocholine O-acyltransferase activity, 0005509=calcium ion binding, 0071617=lysophospholipid acyltransferase activity" "0008654=phospholipid biosynthetic process, 0030258=lipid modification" "0005811=lipid particle, 0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "Lyso-PA acyltransferase, CG15318, CG32699, CG18535, LPCAT1/2, tok-like, CG2996, CT7882" "IPR002048=EF-hand domain, IPR002123=Phospholipid/glycerol acyltransferase, IPR011992=EF-hand domain pair" CG32699 16-Dec-15 2015_12 "ENSDARG00000011506(lpcat1),ENSDARG00000053010(zgc:112165)" ENSXETG00000001729(LPCAT1) "ENSMUSG00000021608(Lpcat1),ENSMUSG00000033192(Lpcat2),ENSMUSG00000033794(Lpcat2b)" "ENSG00000153395(LPCAT1),ENSG00000087253(LPCAT2)" "viable,fertile,visible" mesothoracic tergum FBgn0030670 Pis Phosphatidylinositol synthase http://flybase.net/reports/FBgn0030670.html FBgn0066023 protein_coding_gene 0003881=CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity "0008654=phospholipid biosynthetic process, 0007602=phototransduction, 0071711=basement membrane organization" 0016020=membrane "CG9245, anon-WO02059370.38, phosphatidylinositol synthase, Phosphatidyl-inositol synthase, Drosophila phosphatidylinositol synthase, dPIS, PI synthase, dpis" "IPR014387=CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote, IPR000462=CDP-alcohol phosphatidyltransferase" CG9245 16-Dec-15 2015_12 ENSDARG00000070686(cdipt) YPR113W(PIS1) WBGene00012897(pisy-1) ENSXETG00000026763(CDIPT) ENSMUSG00000030682(Cdipt) ENSG00000103502(CDIPT) "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,heat sensitive,neurophysiology defective" "eye,somatic clone,eye photoreceptor cell,rhabdomere,rhabdomere, with Pishs.THsapMYC,rhabdomere, with Pis1" FBgn0002704 Me Moire http://flybase.net/reports/FBgn0002704.html gene Mo 16-Dec-15 2015_12 "visible,dominant,lethal,recessive,eye color defective" "eye,pigment cell,macrochaeta" FBgn0053433 5SrRNA:CR33433 5SrRNA:CR33433 http://flybase.net/reports/FBgn0053433.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33433 CR33433 16-Dec-15 2015_12 FBgn0031430 CG3528 http://flybase.net/reports/FBgn0031430.html protein_coding_gene IPR027887=Protein of unknown function DUF4464 CG3528 16-Dec-15 2015_12 ENSG00000197826(C4orf22) FBgn0263615 CR43624 http://flybase.net/reports/FBgn0263615.html non_protein_coding_gene CR43624 16-Dec-15 2015_12 FBgn0010499 l(2)01855 lethal (2) 01855 http://flybase.net/reports/FBgn0010499.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0051463 CG31463 http://flybase.net/reports/FBgn0051463.html FBgn0037564 protein_coding_gene CG11673 CG31463 16-Dec-15 2015_12 "viable,fertile" FBgn0024625 l(3)63Db lethal (3) 63Db http://flybase.net/reports/FBgn0024625.html gene "c.g.15, complementation group 15" 16-Dec-15 2015_12 "lethal,recessive" FBgn0065820 l(2)SH0369 lethal (2) SH0369 http://flybase.net/reports/FBgn0065820.html gene l(2)SH2 0369 16-Dec-15 2015_12 "lethal,recessive" FBgn0266675 CR45165 http://flybase.net/reports/FBgn0266675.html non_protein_coding_gene CR45165 16-Dec-15 2015_12 FBgn0001407 l(1)3Bb lethal (1) 3Bb http://flybase.net/reports/FBgn0001407.html gene "l(1)zw6, zw6, ZW-6, zw-6" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,rescuable maternal effect,partially lethal - majority die,female sterile" tergite FBgn0005379 fs(2)OW207 female sterile (2) OW207 http://flybase.net/reports/FBgn0005379.html gene 16-Dec-15 2015_12 FBgn0085797 CR41540 http://flybase.net/reports/FBgn0085797.html FBan0041540 rRNA_gene CR41540 16-Dec-15 2015_12 FBgn0267935 CR46215 http://flybase.net/reports/FBgn0267935.html non_protein_coding_gene lincRNA.604 CR46215 16-Dec-15 2015_12 FBgn0003699 thl thick legs http://flybase.net/reports/FBgn0003699.html gene 16-Dec-15 2015_12 "visible,male fertile,viable,male,reduced,recessive,eye color defective,body color defective" "wing,leg,metathoracic leg,tibia,tarsal segment,pigment cell" FBgn0039427 CG5447 http://flybase.net/reports/FBgn0039427.html protein_coding_gene 0043001=Golgi to plasma membrane protein transport 0031228=intrinsic component of Golgi membrane IPR019383=Golgin subfamily A member 7/ERF4 CG5447 16-Dec-15 2015_12 "ENSDARG00000057676(golga7),ENSDARG00000031461(si:ch211-286o21.1),ENSDARG00000036295(golga7b)" WBGene00013323(Y57G11C.33) ENSXETG00000007777(GOLGA7) ENSMUSG00000015341(Golga7) "ENSG00000147533(GOLGA7),ENSG00000155265(GOLGA7B)" "viable,fertile" FBgn0064156 mod(Fmr1) modifier of Fmr1 http://flybase.net/reports/FBgn0064156.html gene Ulysses 16-Dec-15 2015_12 FBgn0011450 l(3)neo6 lethal (3) neo6 http://flybase.net/reports/FBgn0011450.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003541 St-SD Stabilizer of Segregation Distorter http://flybase.net/reports/FBgn0003541.html gene St(SD) 16-Dec-15 2015_12 FBgn0260990 yata yata http://flybase.net/reports/FBgn0260990.html "FBgn0039692, FBgn0086225" protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "CG1973, Yata" "IPR011989=Armadillo-like helical, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR016024=Armadillo-type fold" CG1973 16-Dec-15 2015_12 ENSDARG00000009017(LOC100329924) YOR112W(CEX1) WBGene00012337(W07G4.3) ENSXETG00000023113(scyl1) ENSMUSG00000024941(Scyl1) ENSG00000142186(SCYL1) FBgn0260095 2L3244 http://flybase.net/reports/FBgn0260095.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0001462 l(1)7Ec lethal (1) 7Ec http://flybase.net/reports/FBgn0001462.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038002 CG12256 http://flybase.net/reports/FBgn0038002.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP133 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG12256 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0264372 CR43824 http://flybase.net/reports/FBgn0264372.html non_protein_coding_gene CR43824 16-Dec-15 2015_12 FBgn0086257 caps::trn http://flybase.net/reports/FBgn0086257.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0266027 CR44792 http://flybase.net/reports/FBgn0266027.html non_protein_coding_gene CR44792 16-Dec-15 2015_12 FBgn0264482 CR43890 http://flybase.net/reports/FBgn0264482.html non_protein_coding_gene CG43890 CR43890 16-Dec-15 2015_12 FBgn0016804 l(1)K6 lethal (1) K6 http://flybase.net/reports/FBgn0016804.html gene K6 16-Dec-15 2015_12 "lethal,recessive" FBgn0053978 CG33978 http://flybase.net/reports/FBgn0053978.html protein_coding_gene 0005509=calcium ion binding FBgn0053978 "IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR001881=EGF-like calcium-binding domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site" CG33978 16-Dec-15 2015_12 FBgn0263412 CR43458 http://flybase.net/reports/FBgn0263412.html non_protein_coding_gene lincRNA.913 CR43458 16-Dec-15 2015_12 FBgn0084894 Su(dpp)YE31 Su(dpp)YE31 http://flybase.net/reports/FBgn0084894.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic dorsal epidermis,amnioserosa" FBgn0003187 qua quail http://flybase.net/reports/FBgn0003187.html "FBgn0000942, FBgn0044556" protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding" "0007015=actin filament organization, 0007300=ovarian nurse cell to oocyte transport, 0035317=imaginal disc-derived wing hair organization, 0051017=actin filament bundle assembly, 0007303=cytoplasmic transport, nurse cell to oocyte" "0005884=actin filament, 0005737=cytoplasm" "quail, Qua, Quail, anon-WO0140519.71, female sterile(2)A12, fs(2)A12, villin, Villin, CG6433" "IPR003128=Villin headpiece, IPR029006=ADF-H/Gelsolin-like domain, IPR007122=Villin/Gelsolin, IPR030016=Villin-like protein quail" CG6433 16-Dec-15 2015_12 WBGene00010593(gsnl-1) " adult stage | female , adult stage && oogenesis stage , embryonic stage | 0-4 hr , pupal stage , spermatogenesis && adult stage " " ovary

, nurse cell

, testis

, oocyte

" adult stage && oogenesis stage " nurse cell

, oocyte

, ring canal

" "female sterile,recessive,viable,fertile,mitotic cell cycle defective,wild-type,heat sensitive" "nurse cell,egg,egg chamber,nurse follicle cell,oocyte,nurse cell ring canal,actin filament & egg chamber,dorsal appendage,female reproductive system,spindle,nurse cell & actin filament,ovary,wing hair" FBgn0000170 bef ë_ lobes fused http://flybase.net/reports/FBgn0000170.html gene bef[BG17b] 16-Dec-15 2015_12 mushroom body beta-lobe FBgn0036110 Cpr67Fb Cuticular protein 67Fb http://flybase.net/reports/FBgn0036110.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0040003=chitin-based cuticle development, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0031012=extracellular matrix" "DmelCpr67Fb, CG18348" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG18348 16-Dec-15 2015_12 viable FBgn0001549 l(1)16Fc lethal (1) 16Fc http://flybase.net/reports/FBgn0001549.html gene ME-III 16-Dec-15 2015_12 "lethal,maternal effect,uncoordinated,somatic clone,neurophysiology defective,recessive,behavior defective,lethal - all die before end of larval stage,dominant,non-rescuable maternal effect,some die during larval stage" "wing,leg" FBgn0052568 CG32568 http://flybase.net/reports/FBgn0052568.html FBgn0030785 protein_coding_gene 0008601=protein phosphatase type 2A regulator activity "0007165=signal transduction, 0006470=protein dephosphorylation" 0000159=protein phosphatase type 2A complex CG4724 "IPR002554=Protein phosphatase 2A, regulatory B subunit, B56, IPR016024=Armadillo-type fold" CG32568 16-Dec-15 2015_12 viable FBgn0016120 ATPsynD "ATP synthase, subunit D" http://flybase.net/reports/FBgn0016120.html protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0006979=response to oxidative stress, 0015992=proton transport, 0015986=ATP synthesis coupled proton transport, 0032007=negative regulation of TOR signaling, 0070373=negative regulation of ERK1 and ERK2 cascade, 0008340=determination of adult lifespan, 0046034=ATP metabolic process, 0051881=regulation of mitochondrial membrane potential" "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), 0005875=microtubule associated complex, 0005811=lipid particle, 0005739=mitochondrion" "CG6030, ATPase synthase, subunit d, ATPsyn-delta, ATP syn-d, ATP synthase D chain, F0/F1 ATP synthase D, ATP synthase,d, ATP synthase subunits d, ATP SYNTHASE, Subunit d, ATPQ, ATP synthase, subunit d, ATP synthase chain D, ATPsyn-D, ATPsyn-d" "IPR008689=ATPase, F0 complex, subunit D, mitochondrial" CG6030 16-Dec-15 2015_12 ENSDARG00000025635(atp5h) YKL016C(ATP7) WBGene00007385(atp-5) ENSXETG00000012507(Q63ZZ5_XENTR) "ENSMUSG00000034566(Atp5h),ENSMUSG00000068706(Gm10250),ENSMUSG00000061992(Gm4953),ENSMUSG00000061187(Gm5048)" ENSG00000167863(ATP5H) "lethal,visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0005224 l(3)ET26 lethal Elaine Tasaka 26 http://flybase.net/reports/FBgn0005224.html gene 16-Dec-15 2015_12 "lethal,cold sensitive" FBgn0037583 CG9684 http://flybase.net/reports/FBgn0037583.html protein_coding_gene 0008270=zinc ion binding "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "IPR002893=Zinc finger, MYND-type, IPR002999=Tudor domain" CG9684 16-Dec-15 2015_12 "viable,fertile" FBgn0043061 Tl::Toll-7 Tl::Toll-7 http://flybase.net/reports/FBgn0043061.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0040531 CG11741 http://flybase.net/reports/FBgn0040531.html protein_coding_gene CG11741 16-Dec-15 2015_12 FBgn0001693 l(1)ESHS14 lethal (1) ESHS14 http://flybase.net/reports/FBgn0001693.html gene 2/16B/1 16-Dec-15 2015_12 "lethal,recessive" FBgn0005715 l(1)TK119 lethal (1) TK119 http://flybase.net/reports/FBgn0005715.html gene l119 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0010730 l(3)00836 lethal (3) 00836 http://flybase.net/reports/FBgn0010730.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016755 Toki Toki http://flybase.net/reports/FBgn0016755.html gene 16-Dec-15 2015_12 "behavior defective,semidominant" FBgn0266282 jnj java no jive http://flybase.net/reports/FBgn0266282.html "FBgn0062269, FBgn0039164" protein_coding_gene "0003684=damaged DNA binding, 0019789=SUMO transferase activity" "0000724=double-strand break repair via homologous recombination, 0006974=cellular response to DNA damage stimulus, 0006281=DNA repair, 0031000=response to caffeine" "0005634=nucleus, 0030915=Smc5-Smc6 complex" "huc[95E], HU- or caffeine-sensitive 95E, huc[95DE], HU- and caffeine-dependent 95D-E, SMC6, Smc6, huc95E, hydroxyurea- and (or) caffeine-sensitive 95E, CG5524, huc[95D-E], Huc-95DE, AAF56254" "IPR003395=RecF/RecN/SMC, N-terminal, IPR027132=Structural maintenance of chromosomes protein 6, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG5524 16-Dec-15 2015_12 "ENSDARG00000058807,ENSDARG00000058719(si:dkey-119f1.1)" YLR383W(SMC6) "WBGene00010056(F54D5.14),WBGene00007694(C23H4.6)" ENSXETG00000015569(SMC6) ENSMUSG00000020608(Smc6) ENSG00000163029(SMC6) FBgn0034655 CG10307 http://flybase.net/reports/FBgn0034655.html protein_coding_gene CT28947 IPR001611=Leucine-rich repeat CG10307 16-Dec-15 2015_12 "ENSDARG00000063569(LOC798319),ENSDARG00000045612(lrrc10)" "ENSXETG00000001408(LRRC10),ENSXETG00000008831(LRRC10B)" "ENSMUSG00000032495(Lrrc2),ENSMUSG00000027961(Lrrc39)" "ENSG00000198812(LRRC10),ENSG00000204950(LRRC10B)" viable DRSC04057 I 1.55075864 0.879384006 0.111249523 -0.498188965 0.764813819 -0.414527188 FBgn0267633 CR45971 http://flybase.net/reports/FBgn0267633.html non_protein_coding_gene CR45971 16-Dec-15 2015_12 FBgn0066323 val valiet http://flybase.net/reports/FBgn0066323.html gene "0048149=behavioral response to ethanol, 0007611=learning or memory, 0008355=olfactory learning" valiet-1 16-Dec-15 2015_12 "memory defective,chemical sensitive,neurophysiology defective" FBgn0011054 l(1)Q7 lethal (1) Q7 http://flybase.net/reports/FBgn0011054.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0031803 ppk14 pickpocket 14 http://flybase.net/reports/FBgn0031803.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "CG9501, PPK14" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG9501 16-Dec-15 2015_12 viable FBgn0015342 anon-84Aa anon-84Aa http://flybase.net/reports/FBgn0015342.html gene 16-Dec-15 2015_12 FBgn0259104 dar5 dendritic arbor reduction 5 http://flybase.net/reports/FBgn0259104.html gene 0050775=positive regulation of dendrite morphogenesis 16-Dec-15 2015_12 FBgn0070003 BG01564 BG01564 http://flybase.net/reports/FBgn0070003.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "stress response defective,viable,smell perception defective" FBgn0065661 l(2)SH0713 lethal (2) SH0713 http://flybase.net/reports/FBgn0065661.html gene l(2)SH2 0713 16-Dec-15 2015_12 "lethal,recessive" FBgn0052091 CG32091 http://flybase.net/reports/FBgn0052091.html "FBgn0036185, FBgn0040818" protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "CG14136, CG7346" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR013525=ABC-2 type transporter" CG32091 16-Dec-15 2015_12 "viable,fertile" FBgn0041595 l(2)SK1 lethal (2) SK1 http://flybase.net/reports/FBgn0041595.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000704 fltJ flight defective J http://flybase.net/reports/FBgn0000704.html gene 16-Dec-15 2015_12 flight defective FBgn0038508 CG5866 http://flybase.net/reports/FBgn0038508.html protein_coding_gene CG5866 16-Dec-15 2015_12 viable DRSC15900 K -0.038468962 -0.736576263 -0.392729477 -0.0490764 1.512516356 0.905920438 FBgn0259184 CG42288 http://flybase.net/reports/FBgn0259184.html "FBan0013353, FBgn0033896" protein_coding_gene CG13353 CG42288 16-Dec-15 2015_12 viable FBgn0052351 S-Lap2 Sperm-Leucylaminopeptidase 2 http://flybase.net/reports/FBgn0052351.html "FBgn0044541, FBgn0064133" protein_coding_gene "0008235=metalloexopeptidase activity, 0004177=aminopeptidase activity, 0030145=manganese ion binding" 0006508=proteolysis 0005737=cytoplasm "Sperm-LeucylAminoPeptidase 2, BcDNA:LP03301, anon-WO0140519.85, S-LAP 2, CG32351, Lap CG32351" "IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal" CG32351 16-Dec-15 2015_12 ENSDARG00000061981(lap3) ENSXETG00000020343(lap3) ENSMUSG00000039682(Lap3) ENSG00000002549(LAP3) viable FBgn0263400 CG43446 http://flybase.net/reports/FBgn0263400.html protein_coding_gene "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG43446 16-Dec-15 2015_12 FBgn0266623 CR45130 http://flybase.net/reports/FBgn0266623.html non_protein_coding_gene CR45130 16-Dec-15 2015_12 FBgn0043977 Su(tor)321-16-5 Su(tor)321-16-5 http://flybase.net/reports/FBgn0043977.html gene 321-16-5 16-Dec-15 2015_12 FBgn0051679 Tengl3 Testis EndoG-Like 3 http://flybase.net/reports/FBgn0051679.html FBgn0031404 protein_coding_gene "0003676=nucleic acid binding, 0004520=endodeoxyribonuclease activity, 0046872=metal ion binding" 0005739=mitochondrion "CG31679, CG17006" "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG31679 16-Dec-15 2015_12 "viable,fertile" FBgn0053123 CG33123 http://flybase.net/reports/FBgn0053123.html "FBgn0025535, FBgn0031543" protein_coding_gene "0002161=aminoacyl-tRNA editing activity, 0004823=leucine-tRNA ligase activity, 0005524=ATP binding" "0022008=neurogenesis, 0042060=wound healing, 0006429=leucyl-tRNA aminoacylation" "0017101=aminoacyl-tRNA synthetase multienzyme complex, 0005875=microtubule associated complex, 0005737=cytoplasm" "CG3229, LeuRS, anon-EST:Posey266" "IPR015413=Methionyl/Leucyl tRNA synthetase, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR013155=Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR004493=Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic, IPR002300=Aminoacyl-tRNA synthetase, class Ia, IPR009008=Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain" CG33123 16-Dec-15 2015_12 ENSDARG00000019280(lars) YPL160W(CDC60) WBGene00003073(lars-1) ENSXETG00000002320(lars) ENSMUSG00000024493(Lars) ENSG00000133706(LARS) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000633 fas faint sausage http://flybase.net/reports/FBgn0000633.html FBgn0010603 protein_coding_gene "0007510=cardioblast cell fate determination, 0007443=Malpighian tubule morphogenesis, 0007391=dorsal closure, 0008258=head involution, 0007431=salivary gland development, 0042250=maintenance of polarity of embryonic epithelium, 0002009=morphogenesis of an epithelium, 0007440=foregut morphogenesis, 0007435=salivary gland morphogenesis" "l(2)05488, CG17716, CT39263, l(2)5488" "IPR013098=Immunoglobulin I-set, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR007110=Immunoglobulin-like domain" CG17716 16-Dec-15 2015_12 "ENSDARG00000070367(bcam),ENSDARG00000026531(alcama),ENSDARG00000069491,ENSDARG00000058538(alcamb)" "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "interface glial cell,aCC neuron,pCC neuron,MP1 neuron,dMP2 neuron,vMP2 neuron,Malpighian tubule primordium,Malpighian tubule,presumptive embryonic/larval digestive system,embryonic/larval foregut,embryonic/larval proventriculus,midgut constriction,embryonic head,dorsal closure embryo,embryonic epidermis,embryonic/larval salivary gland,embryonic/larval posterior spiracle,adult salivary gland primordium,cardioblast,embryonic/larval pericardial cell,external sensory organ,trichogen cell,tormogen cell,eo neuron,ventral nerve cord,ventral nerve cord commissure,ventral midline,embryonic/first instar larval cuticle,embryonic/larval esophagus,keyhole structure,embryonic/larval hindgut" FBgn0020391 Nrk Neurospecific receptor kinase http://flybase.net/reports/FBgn0020391.html "FBgn0021861, FBgn0022790, FBgn0082206" protein_coding_gene "0005524=ATP binding, 0004714=transmembrane receptor protein tyrosine kinase activity, 0004713=protein tyrosine kinase activity" "0046716=muscle cell cellular homeostasis, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0007165=signal transduction, 0072499=photoreceptor cell axon guidance, 0006468=protein phosphorylation, 0042052=rhabdomere development" 0005886=plasma membrane "nrk, DmHD-434, neurospecific receptor tyrosine kinase, Neuronal receptor kinase, CG4007, ROR2, DNRK, HD-434, anon-WO2004063362.79, l(2)k14301, nrtk_dros, Drosophila neurospecific receptor kinase, Dnrk" "IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain, IPR000001=Kringle, IPR016247=Tyrosine-protein kinase, receptor ROR, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR018056=Kringle, conserved site, IPR013806=Kringle-like fold, IPR020067=Frizzled domain" CG4007 16-Dec-15 2015_12 ENSDARG00000000102(musk) ENSMUSG00000057280(Musk) ENSG00000030304(MUSK) " embryonic stage -- adult stage , embryonic stage | stage >=10 , embryonic stage | stage 17 " " neurogenic region

, embryonic central nervous system

, peripheral nervous system

" "lethal,recessive,viable" FBgn0033614 Obp47b Odorant-binding protein 47b http://flybase.net/reports/FBgn0033614.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp47b, CG13208" IPR006170=Pheromone/general odorant binding protein CG13208 16-Dec-15 2015_12 DRSC27574 K -0.569382885 0.036594396 -0.141242658 0.545977019 -1.751191302 -1.209422814 FBgn0028416 Met75Ca Met75Ca http://flybase.net/reports/FBgn0028416.html FBgn0052197 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG32197 CG32197 16-Dec-15 2015_12 DRSC09549 IE 1.588241685 1.251812384 1.544626368 -0.566911988 -0.583411236 -1.042212316 FBgn0036462 mRpL39 mitochondrial ribosomal protein L39 http://flybase.net/reports/FBgn0036462.html protein_coding_gene "0000166=nucleotide binding, 0003735=structural constituent of ribosome, 0004829=threonine-tRNA ligase activity" "0006435=threonyl-tRNA aminoacylation, 0006412=translation" 0005762=mitochondrial large ribosomal subunit "mitochondrial ribosomal protein L5, CG17166, MRP-L5, mRpL5" "IPR012675=Beta-grasp domain, IPR018163=Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain" CG17166 16-Dec-15 2015_12 ENSDARG00000041570(mrpl39) WBGene00044344(Y46H3A.7) ENSXETG00000005956(mrpl39) ENSMUSG00000022889(Mrpl39) ENSG00000154719(MRPL39) "viable,visible" trichogen cell FBgn0002319 l(3)85Ec lethal (3) 85Ec http://flybase.net/reports/FBgn0002319.html gene "l(3)SG39, l(3)WG89" 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0086368 tw Protein O-mannosyltransferase 2 http://flybase.net/reports/FBgn0086368.html "FBgn0003898, FBgn0025618" protein_coding_gene 0004169=dolichyl-phosphate-mannose-protein mannosyltransferase activity "0016203=muscle attachment, 0035269=protein O-linked mannosylation, 0045214=sarcomere organization, 0007525=somatic muscle development" "0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0016020=membrane" "dPOMT2, DPOMT2, Protein O-mannosyltransferase 2, dPomt2, Tw, tricky-dickey, Pomt2, CG12311, DmPOMT2, POMT2, EG:34F3.7, twisted, Twisted" "IPR016093=MIR motif, IPR027005=Glycosyltransferase 39-like, IPR003342=Glycosyl transferase family 39/83" CG12311 16-Dec-15 2015_12 ENSDARG00000055027(pomt2) "YAL023C(PMT2),YOR321W(PMT3),YGR199W(PMT6)" ENSMUSG00000034126(Pomt2) ENSG00000009830(POMT2) FBgn0039421 CG6036 http://flybase.net/reports/FBgn0039421.html protein_coding_gene "0030145=manganese ion binding, 0000287=magnesium ion binding, 0004722=protein serine/threonine phosphatase activity" 0006470=protein dephosphorylation "0005634=nucleus, 0005737=cytoplasm" PP2Cb "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C, IPR012911=Protein serine/threonine phosphatase 2C, C-terminal, IPR000222=PPM-type phosphatase, divalent cation binding" CG6036 16-Dec-15 2015_12 WBGene00006460(tag-93) viable DRSC15953 E 1.142935774 0.347711612 0.50088674 1.54585224 -0.059358432 -1.013672335 FBgn0015882 anon-64Bd anon-64Bd http://flybase.net/reports/FBgn0015882.html gene 16-Dec-15 2015_12 adult stage " leg

, adult head

, antenna

" FBgn0265104 CR44206 http://flybase.net/reports/FBgn0265104.html non_protein_coding_gene "CG44206, pri-mir-184" CR44206 16-Dec-15 2015_12 FBgn0033249 CG11191 http://flybase.net/reports/FBgn0033249.html protein_coding_gene CG11191 16-Dec-15 2015_12 viable DRSC28710 K -0.741731338 -0.235065846 0.453517938 -0.425222631 1.759052613 0.816105004 FBgn0017384 l(1)15Fa lethal (1) 15Fa http://flybase.net/reports/FBgn0017384.html gene 16-Dec-15 2015_12 lethal FBgn0058174 CG40174 http://flybase.net/reports/FBgn0058174.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263878 l(3)LVC73 http://flybase.net/reports/FBgn0263878.html gene 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage" "embryonic/larval neuroblast,embryonic/larval brain,embryonic/larval optic lobe" FBgn0058225 CG40225 http://flybase.net/reports/FBgn0058225.html FBan0040225 protein_coding_gene 16-Dec-15 2015_12 FBgn0034144 CG5089 http://flybase.net/reports/FBgn0034144.html FBgn0044707 protein_coding_gene "anon-WO0140519.170, CG5089s" CG5089 16-Dec-15 2015_12 viable FBgn0030543 CG11585 http://flybase.net/reports/FBgn0030543.html protein_coding_gene CG11585 16-Dec-15 2015_12 viable FBgn0260460 mRpS34 mitochondrial ribosomal protein S34 http://flybase.net/reports/FBgn0260460.html FBgn0036613 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "MRP-S34, CG13037" CG42648 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0005705 l(1)TK108 lethal (1) TK108 http://flybase.net/reports/FBgn0005705.html gene l108 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0053054 CG33054 http://flybase.net/reports/FBgn0053054.html "FBgn0037056, FBgn0037058, FBgn0064118" protein_coding_gene "CG10167, CG10517" IPR002589=Macro domain CG33054 16-Dec-15 2015_12 ENSDARG00000057426(zgc:110708) ENSMUSG00000040771(AI314976) ENSG00000124596(C6orf130) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0038499 Brf Brf http://flybase.net/reports/FBgn0038499.html "FBgn0038502, FBgn0051256" protein_coding_gene "0008134=transcription factor binding, 0001046=core promoter sequence-specific DNA binding, 0017025=TBP-class protein binding, 0008270=zinc ion binding" "0006359=regulation of transcription from RNA polymerase III promoter, 0006383=transcription from RNA polymerase III promoter, 0006384=transcription initiation from RNA polymerase III promoter, 0048812=neuron projection morphogenesis" "0005634=nucleus, 0000126=transcription factor TFIIIB complex, 0005667=transcription factor complex" "TFIIIB, CG31256, BRF1, CG4155, Brf1, RNA Pol III transcription factor, CG5419, BRF, brf" "IPR011665=Brf1, TBP-binding domain, IPR013150=Transcription factor TFIIB, cyclin-like domain, IPR000812=Transcription factor TFIIB, IPR013137=Zinc finger, TFIIB-type, IPR029529=Transcription factor IIIB subunit Brf1, IPR013763=Cyclin-like" CG31256 16-Dec-15 2015_12 "ENSDARG00000005002(zgc:63497),ENSDARG00000017835" YGR246C(BRF1) WBGene00000271(brf-1) ENSXETG00000022549(BRF1) ENSMUSG00000011158(Brf1) ENSG00000185024(BRF1) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0004022 Wr Wrinkle http://flybase.net/reports/FBgn0004022.html gene Wrinkled 16-Dec-15 2015_12 "viable,recessive,developmental rate defective" wing FBgn0063925 Jra::kay Jra::kay http://flybase.net/reports/FBgn0063925.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0266252 CR44947 http://flybase.net/reports/FBgn0266252.html non_protein_coding_gene lincRNA.822 CR44947 16-Dec-15 2015_12 FBgn0266577 CR45108 http://flybase.net/reports/FBgn0266577.html non_protein_coding_gene CR45108 16-Dec-15 2015_12 FBgn0036661 CG9705 http://flybase.net/reports/FBgn0036661.html protein_coding_gene 0003677=DNA binding "0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated" "IPR011129=Cold shock protein, IPR002059=Cold-shock protein, DNA-binding, IPR019844=Cold-shock conserved site, IPR012340=Nucleic acid-binding, OB-fold" CG9705 16-Dec-15 2015_12 "ENSDARG00000053129(carhsp1),ENSDARG00000068477,ENSDARG00000041323(csdc2)" ENSXETG00000008696(CARHSP1) "ENSMUSG00000008393(Carhsp1),ENSMUSG00000042109(Csdc2)" "ENSG00000153048(CARHSP1),ENSG00000172346(CSDC2)" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB" FBgn0024904 anon-I7114 anon-I7114 http://flybase.net/reports/FBgn0024904.html gene cDNA I7114 16-Dec-15 2015_12 FBgn0022711 61bis 61bis http://flybase.net/reports/FBgn0022711.html gene 16-Dec-15 2015_12 FBgn0017625 Eig58C Eig58C http://flybase.net/reports/FBgn0017625.html gene "Ecdysone-induced gene 58C, Eig58" 16-Dec-15 2015_12 FBgn0266880 CR45341 http://flybase.net/reports/FBgn0266880.html non_protein_coding_gene CR45341 16-Dec-15 2015_12 FBgn0001535 l(1)14Ba lethal (1) 14Ba http://flybase.net/reports/FBgn0001535.html gene 16-Dec-15 2015_12 lethal FBgn0036875 CG9449 http://flybase.net/reports/FBgn0036875.html protein_coding_gene 0003993=acid phosphatase activity "0006909=phagocytosis, 0016311=dephosphorylation" "0005634=nucleus, 0070062=extracellular exosome" "IPR000560=Histidine phosphatase superfamily, clade-2, IPR029033=Histidine phosphatase superfamily, IPR029630=Venom acid phosphatase Acph-1" CG9449 16-Dec-15 2015_12 WBGene00015161(pho-5) viable FBgn0004422 gustC gustatory-defective C http://flybase.net/reports/FBgn0004422.html "FBgn0001155, FBgn0001160" gene "gust[x2], gusB" 16-Dec-15 2015_12 "taste perception defective,recessive" FBgn0025127 su(RpII140Z36)S2 su(RpII140Z36)S2 http://flybase.net/reports/FBgn0025127.html gene Z36[S2] 16-Dec-15 2015_12 FBgn0040768 CG13234 http://flybase.net/reports/FBgn0040768.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036108 Cpr67Fa1 Cuticular protein 67Fa1 http://flybase.net/reports/FBgn0036108.html FBgn0047085 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr67Fa1, BcDNA:RE57116, CG7941" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG7941 16-Dec-15 2015_12 FBgn0261456 hpo hippo http://flybase.net/reports/FBgn0261456.html "FBgn0034453, FBgn0069363" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0042803=protein homodimerization activity, 0016301=kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" "2001235=positive regulation of apoptotic signaling pathway, 2001233=regulation of apoptotic signaling pathway, 0002011=morphogenesis of an epithelial sheet, 0007298=border follicle cell migration, 0072089=stem cell proliferation, 0045464=R8 cell fate specification, 0042771=intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, 0010212=response to ionizing radiation, 0046666=retinal cell programmed cell death, 0008285=negative regulation of cell proliferation, 0097202=activation of cysteine-type endopeptidase activity, 0001654=eye development, 0042127=regulation of cell proliferation, 0060253=negative regulation of glial cell proliferation, 0035265=organ growth, 0006915=apoptotic process, 0046621=negative regulation of organ growth, 0045892=negative regulation of transcription, DNA-templated, 0018107=peptidyl-threonine phosphorylation, 0070613=regulation of protein processing, 0046777=protein autophosphorylation, 0043524=negative regulation of neuron apoptotic process, 0008283=cell proliferation, 0006468=protein phosphorylation" 0005737=cytoplasm "MST2, Hpo, hipo, Hippo kinase, MST, Hippo, CG11228, dMST" "IPR011524=SARAH domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR024205=Mst1 SARAH domain, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG11228 16-Dec-15 2015_12 ENSDARG00000011312(stk3) "YIL095W(PRK1),YNL020C(ARK1)" "WBGene00017472(cst-1),WBGene00016038(cst-2)" "ENSXETG00000017844(),ENSXETG00000022832(stk4)" "ENSMUSG00000022329(Stk3),ENSMUSG00000018209(Stk4)" "ENSG00000104375(STK3),ENSG00000101109(STK4)" larval stage | third instar imaginal disc

FBgn0002486 l(3)SG46 lethal (3) SG46 http://flybase.net/reports/FBgn0002486.html gene l(3)g21 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "ventral thoracic disc,imaginal disc" FBgn0025871 B52::tra2 B52::tra2 http://flybase.net/reports/FBgn0025871.html engineered_fusion_gene TRA-2/dSRp55 16-Dec-15 2015_12 FBgn0035084 CG15861 http://flybase.net/reports/FBgn0035084.html protein_coding_gene IPR000742=EGF-like domain CG15861 16-Dec-15 2015_12 "viable,fertile" FBgn0014238 l(2)31Eu lethal (2) 31Eu http://flybase.net/reports/FBgn0014238.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034580 Cht8 Cht8 http://flybase.net/reports/FBgn0034580.html protein_coding_gene "0004568=chitinase activity, 0008061=chitin binding" "0006032=chitin catabolic process, 0005975=carbohydrate metabolic process" 0005576=extracellular region CG9357 "IPR017853=Glycoside hydrolase superfamily, IPR001579=Glycoside hydrolase, chitinase active site, IPR029070=Chitinase insertion domain, IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR002557=Chitin binding domain" CG9357 16-Dec-15 2015_12 "ENSDARG00000009612(zgc:55406),ENSDARG00000031586(zgc:55941),ENSDARG00000008541(zgc:65788),ENSDARG00000070962(zgc:173927),ENSDARG00000027768(zgc:63792),ENSDARG00000046129(zgc:56053)" YDR371W(CTS2) "ENSMUSG00000062778(Chia),ENSMUSG00000043873(Bclp2),ENSMUSG00000040809(Chi3l3),ENSMUSG00000063779(Chi3l4),ENSMUSG00000027902(BC051070),ENSMUSG00000026450(Chit1),ENSMUSG00000074340(Ovgp1)" "ENSG00000134216(CHIA),ENSG00000133063(CHIT1),ENSG00000064886(CHI3L2),ENSG00000133048(CHI3L1),ENSG00000085465(OVGP1)" viable FBgn0002167 l(2)Sp9d lethal (2) Sp9d http://flybase.net/reports/FBgn0002167.html gene 16-Dec-15 2015_12 lethal FBgn0264883 CR44074 http://flybase.net/reports/FBgn0264883.html non_protein_coding_gene CR44074 16-Dec-15 2015_12 FBgn0029824 CG3726 http://flybase.net/reports/FBgn0029824.html protein_coding_gene 0003677=DNA binding "IPR017956=AT hook, DNA-binding motif, IPR009057=Homeodomain-like, IPR007889=DNA binding HTH domain, Psq-type, IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG3726 16-Dec-15 2015_12 ENSXETG00000017921(ZBTB44) "viable,fertile,body color defective" mesothoracic tergum FBgn0264481 CR43889 http://flybase.net/reports/FBgn0264481.html non_protein_coding_gene CR43889 16-Dec-15 2015_12 FBgn0085660 CG41500 http://flybase.net/reports/FBgn0085660.html FBan0041500 protein_coding_gene 16-Dec-15 2015_12 FBgn0001437 l(1)7Be lethal (1) 7Be http://flybase.net/reports/FBgn0001437.html gene l(1)DC829 16-Dec-15 2015_12 lethal FBgn0033744 Dh44-R2 Diuretic hormone 44 receptor 2 http://flybase.net/reports/FBgn0033744.html "FBgn0033743, FBgn0046620, FBgn0046621" protein_coding_gene "0005184=neuropeptide hormone activity, 0008036=diuretic hormone receptor activity, 0008188=neuropeptide receptor activity, 0004948=calcitonin receptor activity, 0004930=G-protein coupled receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0009651=response to salt stress, 0009755=hormone-mediated signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "CRF-like diuretic hormonereceptor 2, CG12370, anon-WO0170980.103, anon-WO0170980.104, CG13156, DH44-R2, DH-R, unnamed, CG1315" "IPR017981=GPCR, family 2-like, IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR002001=GPCR, family 2, diuretic hormone receptor, IPR017983=GPCR, family 2, secretin-like, conserved site, IPR000832=GPCR, family 2, secretin-like" CG12370 16-Dec-15 2015_12 "ENSDARG00000062377,ENSDARG00000003989(crhr1)" "ENSXETG00000005305(CRHR1),ENSXETG00000018502(CRHR2)" "ENSMUSG00000003476(Crhr2),ENSMUSG00000018634(Crhr1)" "ENSG00000106113(CRHR2),ENSG00000120088(CRHR1)" "osmotic stress response defective,viable" FBgn0040801 CG13053 http://flybase.net/reports/FBgn0040801.html protein_coding_gene CG13053 16-Dec-15 2015_12 "viable,fertile" FBgn0040809 CG13465 http://flybase.net/reports/FBgn0040809.html protein_coding_gene CG13465 16-Dec-15 2015_12 FBgn0263911 COX8 Cytochrome c oxidase subunit 8 http://flybase.net/reports/FBgn0263911.html "FBgn0037097, FBgn0062088, FBgn0063245, FBgn0060806" protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" 0005751=mitochondrial respiratory chain complex IV "0554/18, l(3)S055418, lethal (3) S055418, CoVIII, VIII, CG7181, CcO VIIc, Cytochrome c oxidase subunit VIII, anon-WO0118547.331, BcDNA:GH15688, Subunit VIII" "IPR016070=Cytochrome c oxidase subunit VIII/photosystem I reaction centre subunit IX, IPR003205=Cytochrome c oxidase, subunit 8" CG7181 16-Dec-15 2015_12 DRSC11814 K -0.960265869 -1.106376939 -0.955817277 0.024078421 2.193120641 1.985592463 FBgn0003703 thv thick vein http://flybase.net/reports/FBgn0003703.html gene 16-Dec-15 2015_12 "viable,male fertile,female fertile,reduced,visible,recessive,eye color defective,poor,male,body color defective" "wing,wing vein,wing vein L1,wing vein L2,eye,wing hair" FBgn0060776 l(3)S060903 lethal (3) S060903 http://flybase.net/reports/FBgn0060776.html gene 0609/03 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259795 loopin-1 loopin-1 http://flybase.net/reports/FBgn0259795.html "FBgn0034134, FBgn0044545, FBgn0015953" protein_coding_gene "0008235=metalloexopeptidase activity, 0004177=aminopeptidase activity, 0030145=manganese ion binding" 0006508=proteolysis 0005737=cytoplasm "CG4750, kl3lp1, kl-3 loop protein-1, kl3 lp-1, loopin, Sperm-LeucylAminoPeptidase 6, S-LAP 6, anon-WO0140519.81" "IPR011356=Leucine aminopeptidase/peptidase B, IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal" CG4750 16-Dec-15 2015_12 FBgn0013396 anon-94DEa anon-94DEa http://flybase.net/reports/FBgn0013396.html gene anon-94DE 16-Dec-15 2015_12 FBgn0037007 CG5059 http://flybase.net/reports/FBgn0037007.html protein_coding_gene 0043065=positive regulation of apoptotic process "0005740=mitochondrial envelope, 0005634=nucleus, 0016021=integral component of membrane" BNIP3 IPR010548=BNIP3 CG5059 16-Dec-15 2015_12 viable FBgn0036786 skl sickle http://flybase.net/reports/FBgn0036786.html FBgn0047166 protein_coding_gene "0010623=developmental programmed cell death, 0071479=cellular response to ionizing radiation, 0006915=apoptotic process, 0008219=cell death" "Sickle, BcDNA:RE14076, Skl, veto, mephisto, meph, CG13701" CG13701 16-Dec-15 2015_12 "cell death defective,viable,fertile,increased cell death" "EW3 neuron | prepupal stage,EW3 neuron,eye" FBgn0035770 pst pastrel http://flybase.net/reports/FBgn0035770.html protein_coding_gene "0007616=long-term memory, 0007611=learning or memory, 0009306=protein secretion, 0008355=olfactory learning" "0005829=cytosol, 0005811=lipid particle" "pastrel, Dm-65, CG8588" CG8588 16-Dec-15 2015_12 "memory defective,stress response defective" FBgn0004961 l(1)17Ae lethal (1) 17Ae http://flybase.net/reports/FBgn0004961.html gene 16-Dec-15 2015_12 lethal FBgn0050231 tRNA:CR30231 transfer RNA:CR30231 http://flybase.net/reports/FBgn0050231.html "FBgn0050107, FBgn0060229" tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:F:GAA:AE002787-b, AE002787.trna47-PheGAA, CR30107, CR30231, chr2R.trna30-PheGAA" CR30231 16-Dec-15 2015_12 FBgn0261605 M(2)34BC Minute (2) 34BC http://flybase.net/reports/FBgn0261605.html gene 16-Dec-15 2015_12 FBgn0013507 l(1)U10 lethal (1) U10 http://flybase.net/reports/FBgn0013507.html gene U-10 16-Dec-15 2015_12 "lethal,recessive" FBgn0011890 tRNA:K2:42Ad transfer RNA:lys2:42Ad http://flybase.net/reports/FBgn0011890.html "FBgn0003795, FBgn0011886, FBgn0050315, FBgn0050515, FBgn0060188" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Lys][[2]], tRNA:K2, tRNA:K:CTT:AE002769-a, tRNAlys, chr2R.trna94-LysCTT, tRNA:lys2:42Ad, CR30315, CR30515, 35SLys, AE002769.trna3-LysCTT" CR30515 16-Dec-15 2015_12 FBgn0014850 Eig71Ej Eig71Ej http://flybase.net/reports/FBgn0014850.html protein_coding_gene "0042742=defense response to bacterium, 0007552=metamorphosis, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" 0005576=extracellular region "L71-10, CG7588, L71" IPR003475=Insect protein of unknown function CG7588 16-Dec-15 2015_12 viable FBgn0267196 CR45636 http://flybase.net/reports/FBgn0267196.html non_protein_coding_gene lincRNA.790 CR45636 16-Dec-15 2015_12 FBgn0014146 dfk distal of forkhead http://flybase.net/reports/FBgn0014146.html gene dfh 16-Dec-15 2015_12 FBgn0013379 aagp armadillo-associated glycoprotein http://flybase.net/reports/FBgn0013379.html gene 16-Dec-15 2015_12 FBgn0052432 CG32432 http://flybase.net/reports/FBgn0052432.html "FBgn0037032, FBgn0037033, FBgn0037034" protein_coding_gene "CG13257, CG13256, FBgn0037032, CG3116" "IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000859=CUB domain" CG32432 16-Dec-15 2015_12 "viable,fertile" FBgn0260027 CG42495 http://flybase.net/reports/FBgn0260027.html protein_coding_gene CG42495 16-Dec-15 2015_12 FBgn0034770 Obp58d Odorant-binding protein 58d http://flybase.net/reports/FBgn0034770.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp58d, CG13519" CG13519 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0083966 CG34130 http://flybase.net/reports/FBgn0083966.html "FBan0006069, FBgn0039418" protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0032504=multicellular organism reproduction" 0005615=extracellular space "SPH192, CG6069" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG34130 16-Dec-15 2015_12 viable FBgn0033689 CG18342 http://flybase.net/reports/FBgn0033689.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002994 olfQ olfactory Q http://flybase.net/reports/FBgn0002994.html gene 16-Dec-15 2015_12 FBgn0015365 biz bizarre http://flybase.net/reports/FBgn0015365.html gene 0040040=thermosensory behavior SB8 16-Dec-15 2015_12 "hypoactive,behavior defective" FBgn0044511 mRpS21 mitochondrial ribosomal protein S21 http://flybase.net/reports/FBgn0044511.html "FBgn0052854, FBgn0064899" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "BcDNA:RE23482, MRP-S21, CG32854, MrpS21" IPR001911=Ribosomal protein S21 CG32854 16-Dec-15 2015_12 ENSDARG00000070985(zgc:163126) WBGene00017924(F29B9.10) ENSXETG00000028038(mrps21) "ENSMUSG00000054312(Mrps21),ENSMUSG00000049249(Gm5316)" "ENSG00000221879,ENSG00000214298" "viable,visible" trichogen cell DRSC21357 E -0.426059269 0.32651795 0.308568485 -1.556125223 -0.104345499 0.23009066 FBgn0035009 CG16837 http://flybase.net/reports/FBgn0035009.html protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement "0005875=microtubule associated complex, 0030286=dynein complex" IPR004942=Roadblock/LAMTOR2 domain CG16837 16-Dec-15 2015_12 viable DRSC04283 E 0.340083742 -0.00982863 0.106799039 -1.588708857 -0.165432031 0.560633672 FBgn0002991 olfB olfactory B http://flybase.net/reports/FBgn0002991.html gene olfactory-B 16-Dec-15 2015_12 "fertile,smell perception defective,recessive,heat sensitive,viable" FBgn0016684 NaPi-T Na+-dependent inorganic phosphate cotransporter http://flybase.net/reports/FBgn0016684.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0035435=phosphate ion transmembrane transport 0016021=integral component of membrane "Na/Pi-cotransporter, CG10207, Dropo, NapiT, MFS2, Na[+]-dependent inorganic phosphate cotransporter" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain, IPR004745=Na-dependent inorganic phosphate cotransporter" CG10207 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,fertile" FBgn0030980 CG7406 http://flybase.net/reports/FBgn0030980.html protein_coding_gene CG7406 16-Dec-15 2015_12 FBgn0264645 flash-flood flash flood http://flybase.net/reports/FBgn0264645.html gene 0060439=trachea morphogenesis flashflood 16-Dec-15 2015_12 "embryonic/larval lateral trunk,eye,somatic clone" FBgn0000073 Ama-2 ë± Amanitin-resistant 2 http://flybase.net/reports/FBgn0000073.html gene 16-Dec-15 2015_12 FBgn0260577 MENE-X46 http://flybase.net/reports/FBgn0260577.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0019745 l(1)83B lethal (1) 83B http://flybase.net/reports/FBgn0019745.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021799 l(2)k16919 lethal (2) k16919 http://flybase.net/reports/FBgn0021799.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021847 l(2)k14710 lethal (2) k14710 http://flybase.net/reports/FBgn0021847.html FBgn0027519 protein_coding_gene 0022008=neurogenesis "CG8325, l(2)k15603, BcDNA:LD21719" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR013105=Tetratricopeptide repeat 2" CG8325 16-Dec-15 2015_12 ENSDARG00000061207(zgc:153460) WBGene00021444(Y39A3CR.3) ENSXETG00000022746(TTC7A) "ENSMUSG00000033530(Ttc7b),ENSMUSG00000036918(Ttc7)" "ENSG00000165914(TTC7B),ENSG00000068724(TTC7A)" "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0058362 CG40362 http://flybase.net/reports/FBgn0058362.html protein_coding_gene 16-Dec-15 2015_12 FBgn0051583 tRNA:N5:84F tRNA:N5:84F http://flybase.net/reports/FBgn0051583.html "FBgn0003762, FBgn0011941, FBgn0011942, FBgn0011943, FBgn0060134" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033442=AAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:N5:84Fb, tRNA:N5:84Fa, tRNA:N5:84Fc, transfer RNA:asn5:84Fb, tRNA:N:GTT:AE002708, AE002708.trna67-AsnGTT, tRNA:asn5:84Fb, CR31583, chr3R.trna73-AsnGTT, tRNA:asn5:84Fc, transfer RNA:asn5:84Fa, tRNA:asn5:84Fa, transfer RNA:asn5:84Fc" CR31583 16-Dec-15 2015_12 FBgn0264942 CR44111 http://flybase.net/reports/FBgn0264942.html non_protein_coding_gene CR44111 16-Dec-15 2015_12 FBgn0263957 BG01121 http://flybase.net/reports/FBgn0263957.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective,female limited" FBgn0039150 CG13605 http://flybase.net/reports/FBgn0039150.html protein_coding_gene 0008270=zinc ion binding "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR001841=Zinc finger, RING-type" CG13605 16-Dec-15 2015_12 "ENSDARG00000053019(zgc:109947),ENSDARG00000015917(zgc:77306)" WBGene00022502(ZC13.1) "ENSXETG00000026210(TEgg046i15.1),ENSXETG00000011475(RNFT2)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260461 Rcd7 Reduction in Cnn dots 7 http://flybase.net/reports/FBgn0260461.html FBgn0036884 protein_coding_gene "0051299=centrosome separation, 0007283=spermatogenesis" "Reduction in Cnn Dots 7, Rcd7, CG14098" CG14098 16-Dec-15 2015_12 "male sterile,viable" FBgn0032057 CG9287 http://flybase.net/reports/FBgn0032057.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold" CG9287 16-Dec-15 2015_12 "viable,fertile" DRSC03186 I 1.589024852 0.594379983 0.476441683 0.342074121 0.391241399 0.64305324 FBgn0001486 l(1)10Af lethal (1) 10Af http://flybase.net/reports/FBgn0001486.html gene "l(1)G11, l(1)EF444, l(1)EM16" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,maternal effect" FBgn0034276 Sardh Sarcosine dehydrogenase http://flybase.net/reports/FBgn0034276.html protein_coding_gene 0008480=sarcosine dehydrogenase activity "1901053=sarcosine catabolic process, 0055114=oxidation-reduction process, 0033353=S-adenosylmethionine cycle" "sardh, CG6385" "IPR013977=Glycine cleavage T-protein, C-terminal barrel domain, IPR027266=GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1, IPR006222=Glycine cleavage T-protein-like, N-terminal, IPR029043=Glycine cleavage T-protein/YgfZ, C-terminal domain, IPR006076=FAD dependent oxidoreductase" CG6385 16-Dec-15 2015_12 ENSDARG00000058102(sardh) ENSXETG00000023098(SARDH) ENSMUSG00000009614(Sardh) ENSG00000123453(SARDH) viable FBgn0060691 l(3)S073414 lethal (3) S073414 http://flybase.net/reports/FBgn0060691.html gene 0734/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0037939 CG14718 http://flybase.net/reports/FBgn0037939.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0008270=zinc ion binding, 0003676=nucleic acid binding" cg14718 "IPR000504=RNA recognition motif domain, IPR001876=Zinc finger, RanBP2-type, IPR012677=Nucleotide-binding alpha-beta plait domain" CG14718 16-Dec-15 2015_12 viable FBgn0266988 CR45439 http://flybase.net/reports/FBgn0266988.html non_protein_coding_gene CR45439 16-Dec-15 2015_12 FBgn0264514 CR43913 http://flybase.net/reports/FBgn0264514.html non_protein_coding_gene lincRNA.537 CR43913 16-Dec-15 2015_12 FBgn0034576 ND-B14.7 NADH dehydrogenase (ubiquinone) B14.7 subunit http://flybase.net/reports/FBgn0034576.html FBgn0061375 protein_coding_gene "NADH ubiquinone oxidoreductase B14.7, BcDNA:RH51452, CG9350" CG9350 16-Dec-15 2015_12 ENSDARG00000042777 ENSXETG00000021885() "ENSMUSG00000002379(Ndufa11),ENSMUSG00000068487(Gm4943)" ENSG00000213496 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC04544 IE -0.396405947 -2.465681724 -2.716906957 0.192276773 1.489031791 0.538901356 FBgn0267884 CR46172 http://flybase.net/reports/FBgn0267884.html pseudogene_attribute CG12717-related CR46172 16-Dec-15 2015_12 FBgn0082371 EP2522 EP2522 http://flybase.net/reports/FBgn0082371.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0058330 CG40330 http://flybase.net/reports/FBgn0058330.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263116 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B http://flybase.net/reports/FBgn0263116.html "FBgn0050126, FBgn0004572" protein_coding_gene "0004993=serotonin receptor activity, 0008227=G-protein coupled amine receptor activity, 0001586=Gi/o-coupled serotonin receptor activity" "0009649=entrainment of circadian clock, 0007210=serotonin receptor signaling pathway, 0007208=phospholipase C-activating serotonin receptor signaling pathway, 0007198=adenylate cyclase-inhibiting serotonin receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "5HT-dro[[2B]], 5HT1B, 5-HT[[1B]]Dro, Serotonin receptor 1B, 5-HT[[1B]]DRO, Dm5HTdro2B, Serotonin receptor 2B, CG15113, 5-HT[[dro2B]], 5-HT1BDro, d5-HT1B, 5-HT[[1BDro]], 5-HT[1B]Dro, 5HT-dro2B, 5-HT-dro2B, 5-HT[[1B]], 5HT-R2B, DRO2B, 5htdro2b, Drosophila serotonin receptor 1B, CG30126" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG15113 16-Dec-15 2015_12 "ENSDARG00000034438(htr1aa),ENSDARG00000057098" WBGene00004779(ser-4) "ENSMUSG00000049511(Htr1b),ENSMUSG00000070687(Htr1d),ENSMUSG00000050783(Htr1f),ENSMUSG00000021721(Htr1a)" ENSG00000178394(HTR1A) " embryonic stage | stage 16,17 " " bipolar dendrite neuron

, ventral midline

" FBgn0063381 snoRNA:Me28S-G3081a http://flybase.net/reports/FBgn0063381.html snoRNA_gene "U31snoRNA, DmSnR67, CR32887, Dm_28S.041, Me28S-G3081a(U31), snoRNA:U31:54Ea" CR32887 16-Dec-15 2015_12 FBgn0259555 GG01052 http://flybase.net/reports/FBgn0259555.html gene 16-Dec-15 2015_12 visible "unguis,leg,mesothoracic tergum,arista,eye,wing margin" FBgn0029936 CG4617 http://flybase.net/reports/FBgn0029936.html protein_coding_gene IPR009071=High mobility group box domain CG4617 16-Dec-15 2015_12 ENSMUSG00000034518(Hmgxb4) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0003336 scp scooped http://flybase.net/reports/FBgn0003336.html gene 16-Dec-15 2015_12 visible wing FBgn0031723 CG7251 http://flybase.net/reports/FBgn0031723.html FBgn0044781 protein_coding_gene "bs11h10.y1, anon-WO0140519.103" CG7251 16-Dec-15 2015_12 viable FBgn0036459 CG3349 http://flybase.net/reports/FBgn0036459.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG3349 16-Dec-15 2015_12 viable FBgn0039714 Zip99C Zinc/iron regulated transporter-related protein 99C http://flybase.net/reports/FBgn0039714.html protein_coding_gene 0005381=iron ion transmembrane transporter activity "0055085=transmembrane transport, 0060586=multicellular organismal iron ion homeostasis, 0006826=iron ion transport" "0005783=endoplasmic reticulum, 0005622=intracellular, 0005794=Golgi apparatus, 0016323=basolateral plasma membrane, 0016021=integral component of membrane" "CG7816, dZIP13, dZip99C, cg7816" IPR003689=Zinc/iron permease CG7816 16-Dec-15 2015_12 ENSDARG00000000442(slc39a13) ENSXETG00000007914(SLC39A13) ENSMUSG00000002105(Slc39a13) ENSG00000165915(SLC39A13) viable FBgn0265961 CR44748 http://flybase.net/reports/FBgn0265961.html non_protein_coding_gene CR44748 16-Dec-15 2015_12 FBgn0065978 iab-7E.s iab-7E.s http://flybase.net/reports/FBgn0065978.html gene 7E-s 16-Dec-15 2015_12 FBgn0265368 CR44309 http://flybase.net/reports/FBgn0265368.html non_protein_coding_gene lincRNA.24 CR44309 16-Dec-15 2015_12 FBgn0002381 l(3)93Ca lethal (3) 93Ca http://flybase.net/reports/FBgn0002381.html gene "er6, l(3)er6" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001139 gro groucho http://flybase.net/reports/FBgn0001139.html "FBgn0019999, FBgn0020008, FBgn0023439, FBgn0043006, FBgn0043009, FBgn0062049" protein_coding_gene "0003714=transcription corepressor activity, 0005515=protein binding, 0071837=HMG box domain binding, 0070491=repressing transcription factor binding, 0001106=RNA polymerase II transcription corepressor activity, 0003677=DNA binding, 0008134=transcription factor binding" "0007015=actin filament organization, 0046331=lateral inhibition, 0045879=negative regulation of smoothened signaling pathway, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated, 0007399=nervous system development, 0048813=dendrite morphogenesis, 0030178=negative regulation of Wnt signaling pathway, 0007541=sex determination, primary response to X:A ratio, 0090090=negative regulation of canonical Wnt signaling pathway" "0005634=nucleus, 0043234=protein complex" "Grg/TLE, BEST:LD15161, dAES2, BcDNA:LD33829, anon-WO0118547.385, BcDNA.LD33829, l(3)gro, E(spl)gro, Gro, E(spl)[2], m9/10, m9-m10, DGro, Groucho, m9/m10, E(spl)m9/m10, dGro, m9,m10, GRO, E(spl)-WD, m10, En-spl, BEST:GM01575, dAES1, Dgroucho, CG8384, m9" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR009146=Groucho/transducin-like enhancer, IPR005617=Groucho/TLE, N-terminal Q-rich domain, IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site" CG8384 16-Dec-15 2015_12 "ENSDARG00000002787(gro2),ENSDARG00000069006(gro1),ENSDARG00000042484(si:ch211-81i17.1),ENSDARG00000008767(LOC564019)" WBGene00006773(unc-37) "ENSXETG00000010266(tle4),ENSXETG00000014353(tle3),ENSXETG00000013999()" "ENSMUSG00000024642(Tle4),ENSMUSG00000008305(Tle1),ENSMUSG00000032280(Tle3),ENSMUSG00000034771(Tle2)" "ENSG00000140332(TLE3),ENSG00000106829(TLE4),ENSG00000196781(TLE1),ENSG00000065717(TLE2)" " embryonic stage | 2-6 hr , adult stage | female , embryonic stage | early , embryonic stage , embryonic stage | stage <=11 " " central nervous system

, embryonic peripheral nervous system

,

ubiquitous " "lethal,recessive,embryonic/larval segmentation phenotype,maternal effect,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal - all die before end of P-stage,some die during pharate adult stage,neurogenic phenotype,viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority live,dominant,female sterile,partially,male sterile,somatic clone,partially lethal - majority die" "filzkorper,maternal effect,larval head,intermediate ventral neurectoderm,eye,eye photoreceptor cell & eye-antennal discey.PH,eye-antennal disc | late third instar larval stage,head capsule,embryonic/first instar larval cuticle,wing,wing vein L4,wing vein L5,wing margin,wing vein,leg,denticle belt,ocellus,adult head & microchaeta,wing vein L1,wing vein L2,wing vein L3,anterior compartment,dorsal/ventral compartment boundary,macrochaeta & head,macrochaeta & thorax,macrochaeta & abdominal tergite,microchaeta & head,microchaeta & thorax,microchaeta & abdominal tergite,frontal bristle,supernumerary,germline clone,photoreceptor cell,somatic clone,dendrite,sense organ & wing,microchaeta & scutum,macrochaeta & scutum,macrochaeta,ventral nerve cord primordium,ommatidium,embryonic gnathal segment,embryonic epidermis,chaeta,ectopic,mesothoracic tergum,microchaeta,scutellum,anterior postalar bristle,mesothoracic tergum & macrochaeta-C253,sensory mother cell" FBgn0036892 Lon Lon protease http://flybase.net/reports/FBgn0036892.html FBgn0062075 protein_coding_gene "0003697=single-stranded DNA binding, 0005524=ATP binding, 0003727=single-stranded RNA binding, 0004176=ATP-dependent peptidase activity, 0070361=mitochondrial light strand promoter anti-sense binding, 0004252=serine-type endopeptidase activity" "0001666=response to hypoxia, 0051260=protein homooligomerization, 0006515=misfolded or incompletely synthesized protein catabolic process, 0007005=mitochondrion organization, 0070407=oxidation-dependent protein catabolic process, 0034599=cellular response to oxidative stress, 0051131=chaperone-mediated protein complex assembly, 0045732=positive regulation of protein catabolic process" "0005759=mitochondrial matrix, 0005777=peroxisome, 0005739=mitochondrion, 0042645=mitochondrial nucleoid" "anon-WO0118547.350, CG8798, Lon" "IPR027503=Lon protease homolog, chloroplastic/mitochondrial, IPR003593=AAA+ ATPase domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR027065=Lon protease, IPR015947=PUA-like domain, IPR003111=ATP-dependent protease La (LON), substrate-binding domain, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR003959=ATPase, AAA-type, core, IPR004815=Lon protease, bacterial/eukaryotic-type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008268=Peptidase S16, active site, IPR008269=Peptidase S16, Lon C-terminal" CG8798 16-Dec-15 2015_12 ENSDARG00000071674(lonp1) YBL022C(PIM1) WBGene00016391(C34B2.6) ENSXETG00000021888(LONP1) ENSMUSG00000041168(Lonp1) ENSG00000196365(LONP1) "developmental rate defective,RU486 conditional,short lived,male,female,viable,visible" trichogen cell DRSC11049 I -2.01838158 -0.017784196 0.305652778 -0.284613394 0.451557122 -0.237235623 FBgn0002928 Ne Nelson's mutant http://flybase.net/reports/FBgn0002928.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,female,maternal effect,recessive,some die during embryonic stage" FBgn0003879 tu(2)W tumor(2)W http://flybase.net/reports/FBgn0003879.html gene tu-W 16-Dec-15 2015_12 melanotic mass phenotype FBgn0002152 l(2)KX152 lethal (2) KX152 http://flybase.net/reports/FBgn0002152.html gene 16-Dec-15 2015_12 lethal FBgn0265339 CR44293 http://flybase.net/reports/FBgn0265339.html non_protein_coding_gene CR44293 16-Dec-15 2015_12 FBgn0267080 CR45524 http://flybase.net/reports/FBgn0267080.html non_protein_coding_gene CR45524 16-Dec-15 2015_12 FBgn0023158 Su(mg)2-1 Suppressor of modifier of gypsy 2-1 http://flybase.net/reports/FBgn0023158.html gene 16-Dec-15 2015_12 FBgn0035248 CG13919 http://flybase.net/reports/FBgn0035248.html protein_coding_gene IPR019396=Transmembrane Fragile-X-F-associated protein CG13919 16-Dec-15 2015_12 ENSXETG00000025693(TMEM60) ENSMUSG00000045435(Tmem60) ENSG00000135211(TMEM60) viable FBgn0030573 nmdyn-D6 nmdyn-D6 http://flybase.net/reports/FBgn0030573.html protein_coding_gene "0004550=nucleoside diphosphate kinase activity, 0005524=ATP binding" "0009142=nucleoside triphosphate biosynthetic process, 0006165=nucleoside diphosphate phosphorylation, 0006241=CTP biosynthetic process, 0006228=UTP biosynthetic process, 0006183=GTP biosynthetic process" 0005739=mitochondrion CG5310 "IPR023005=Nucleoside diphosphate kinase, active site, IPR001564=Nucleoside diphosphate kinase" CG5310 16-Dec-15 2015_12 ENSDARG00000016138(LOC100330863) WBGene00021692(Y48G8AL.15) ENSXETG00000015714(NME6) ENSMUSG00000032478(Nme6) ENSG00000172113(NME6) viable FBgn0259342 C170 http://flybase.net/reports/FBgn0259342.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0260641 Hsf::nkd http://flybase.net/reports/FBgn0260641.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0005372 x1 x1 http://flybase.net/reports/FBgn0005372.html gene 16-Dec-15 2015_12 FBgn0267513 28SrRNA-ë¬:CR45853 28S ribosomal RNA pseudogene:CR45853 http://flybase.net/reports/FBgn0267513.html pseudogene_attribute CR45853 CR45853 16-Dec-15 2015_12 FBgn0037654 CG11983 http://flybase.net/reports/FBgn0037654.html protein_coding_gene CG11983 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC14458 K 0.637871752 -0.263519958 -0.06034821 0.005325517 -1.525328795 0.521638063 FBgn0032913 CG9259 http://flybase.net/reports/FBgn0032913.html protein_coding_gene "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG9259 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" viable FBgn0052358 tRNA:CR32358 transfer RNA:CR32358 http://flybase.net/reports/FBgn0052358.html FBgn0060156 tRNA_gene 0033420=CUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:L:CAG:AE002602-f, CR32358, AE002602.trna10-LeuCAG, chr3L.trna44-LeuCAG" CR32358 16-Dec-15 2015_12 FBgn0266680 CR45170 http://flybase.net/reports/FBgn0266680.html non_protein_coding_gene CR45170 16-Dec-15 2015_12 FBgn0003026 ovi ovioculus http://flybase.net/reports/FBgn0003026.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced" "egg,wing" FBgn0001131 gr gracile http://flybase.net/reports/FBgn0001131.html gene 16-Dec-15 2015_12 "visible,male sterile,viable,poor" "wing,adult abdomen" FBgn0035692 CG13298 http://flybase.net/reports/FBgn0035692.html protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0048812=neuron projection morphogenesis, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis, 0007052=mitotic spindle organization" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005686=U2 snRNP" cg13298 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG13298 16-Dec-15 2015_12 ENSDARG00000009753(sf3b14) WBGene00016808(C50D2.5) ENSXETG00000018204(TNeu130d21.1) ENSMUSG00000037361(0610009D07Rik) ENSG00000115128(SF3B14) "visible,lethal,neuroanatomy defective,partially lethal - majority die" "wing,wing vein,ectopic,ganglion mother cell,mesothoracic tergum" DRSC09972 I 6.73025579 1.418457494 1.060828269 0.377725373 -1.187746024 -0.706984776 FBgn0035050 ST6Gal Sialyltransferase http://flybase.net/reports/FBgn0035050.html protein_coding_gene "0003835=beta-galactoside alpha-2,6-sialyltransferase activity, 0008373=sialyltransferase activity" "0007528=neuromuscular junction development, 0009311=oligosaccharide metabolic process, 0006486=protein glycosylation" "0005794=Golgi apparatus, 0005576=extracellular region" "D.SiaT, alpha-2,6-sialyltransferase, CG4871, alpha2,6-sialyltransferase, dST6Gal I, DmSialT, b-galactoside-a-2,6-sialyltransferase, DSiaT, sialyltransferase, SialT, D.SialT, sialyltransferase-like, DmPST, dSiaT" "IPR001675=Glycosyl transferase, family 29" CG4871 16-Dec-15 2015_12 "ENSDARG00000039335(st6gal2),ENSDARG00000044514(st6gal1)" "ENSXETG00000003032(ST6GAL1),ENSXETG00000010382(st6gal2)" "ENSMUSG00000022885(St6gal1),ENSMUSG00000024172(St6gal2)" "ENSG00000073849(ST6GAL1),ENSG00000144057(ST6GAL2)" "viable,fertile,short lived,locomotor behavior defective,bang sensitive,paralytic,heat sensitive,neuroanatomy defective,neurophysiology defective,chemical resistant,recessive" "embryonic/larval neuromuscular junction,NMJ bouton" FBgn0015016 Bora-Bora Bora-Bora http://flybase.net/reports/FBgn0015016.html region Bora Bora 16-Dec-15 2015_12 FBgn0263616 CR43625 http://flybase.net/reports/FBgn0263616.html non_protein_coding_gene CR43625 16-Dec-15 2015_12 FBgn0002144 l(2)K335 lethal (2) K335 http://flybase.net/reports/FBgn0002144.html gene 16-Dec-15 2015_12 lethal FBgn0052672 Atg8a Autophagy-related 8a http://flybase.net/reports/FBgn0052672.html "FBgn0030229, FBgn0063168" protein_coding_gene "0019901=protein kinase binding, 0031386=protein tag" "0031396=regulation of protein ubiquitination, 0008340=determination of adult lifespan, 0016236=macroautophagy, 0010506=regulation of autophagy, 0035096=larval midgut cell programmed cell death, 0006914=autophagy" "0044754=autolysosome, 0044753=amphisome, 0034423=autophagic vacuole lumen, 0005776=autophagic vacuole" "ATG8, unnamed, DrAtg8a, CG1534, Autophagy-specific gene 8a, atg8a, LC3, ATG8/LC3, Atg8, atg8A, BcDNA:LD05816, Atg8A, atg8, CG32672, ATG8a, autophagy-related 8a, LC3/Atg8, Atg8/LC3" "IPR004241=Autophagy protein Atg8 ubiquitin-like, IPR029071=Ubiquitin-related domain" CG32672 16-Dec-15 2015_12 "ENSDARG00000052082(LOC793200),ENSDARG00000035557(gabarap)" YBL078C(ATG8) WBGene00002980(lgg-1) ENSXETG00000016242(gabarapl1) ENSMUSG00000018567(Gabarap) ENSG00000170296(GABARAP) "long lived,memory defective,recessive,short lived,male,melanotic mass phenotype,decreased cell death,viable" "embryonic/larval fat body,somatic clone | third instar larval stage,fat body,embryonic/larval salivary gland" FBgn0267780 CR46111 http://flybase.net/reports/FBgn0267780.html non_protein_coding_gene CR46111 16-Dec-15 2015_12 FBgn0263949 BG00767 http://flybase.net/reports/FBgn0263949.html gene 16-Dec-15 2015_12 "long lived,starvation stress response defective,temperature response defective,gravitaxis defective,male limited" FBgn0029798 CG4078 http://flybase.net/reports/FBgn0029798.html protein_coding_gene "0005524=ATP binding, 0004003=ATP-dependent DNA helicase activity, 0003677=DNA binding" "0006260=DNA replication, 0000723=telomere maintenance, 0010569=regulation of double-strand break repair via homologous recombination, 0006289=nucleotide-excision repair" 0005634=nucleus "IPR013020=DNA helicase (DNA repair), Rad3 type, IPR010614=DEAD2, IPR014013=Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR030845=Regulator of telomere elongation helicase 1, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006555=ATP-dependent helicase, C-terminal, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG4078 16-Dec-15 2015_12 ENSDARG00000035074(zgc:113114) WBGene00009124(rtel-1) ENSXETG00000010720(BRIP1) ENSMUSG00000038685(Rtel1) ENSG00000026036(RTEL1) "viable,visible" trichogen cell FBgn0259959 Sfp26Ac Seminal fluid protein 26Ac http://flybase.net/reports/FBgn0259959.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG42469, Seminal fluid protein 26Ac" CG42469 16-Dec-15 2015_12 FBgn0043492 bcd::ftz bcd::ftz http://flybase.net/reports/FBgn0043492.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0031722 CG14011 http://flybase.net/reports/FBgn0031722.html protein_coding_gene 0046331=lateral inhibition CG14011 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0005263 l(3)SG83 lethal (3) SG83 http://flybase.net/reports/FBgn0005263.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052971 CG32971 http://flybase.net/reports/FBgn0052971.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity 0006357=regulation of transcription from RNA polymerase II promoter 0016592=mediator complex IPR009332=Mediator of RNA polymerase II transcription subunit 22 CG32971 16-Dec-15 2015_12 WBGene00007022(mdt-22) viable FBgn0037853 CG14696 http://flybase.net/reports/FBgn0037853.html protein_coding_gene "IPR011022=Arrestin C-terminal-like domain, IPR011021=Arrestin-like, N-terminal, IPR014756=Immunoglobulin E-set" CG14696 16-Dec-15 2015_12 ENSG00000197070(ARRDC1) viable FBgn0265039 CR44156 http://flybase.net/reports/FBgn0265039.html non_protein_coding_gene CR44156 16-Dec-15 2015_12 FBgn0261640 CR42723 http://flybase.net/reports/FBgn0261640.html pseudogene_attribute CR42723 16-Dec-15 2015_12 FBgn0001839 l(1)ts1082 lethal (1) ts1082 http://flybase.net/reports/FBgn0001839.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0265986 CR44765 http://flybase.net/reports/FBgn0265986.html non_protein_coding_gene CR44765 16-Dec-15 2015_12 FBgn0044072 E(rst)J76 E(rst)J76 http://flybase.net/reports/FBgn0044072.html gene 0001745=compound eye morphogenesis J76 16-Dec-15 2015_12 FBgn0069988 BG02063 BG02063 http://flybase.net/reports/FBgn0069988.html gene 16-Dec-15 2015_12 stress response defective FBgn0011365 l(3)j4B9 lethal (3) j4B9 http://flybase.net/reports/FBgn0011365.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030844 ppk23 pickpocket 23 http://flybase.net/reports/FBgn0030844.html protein_coding_gene 0005272=sodium channel activity "0019236=response to pheromone, 0006814=sodium ion transport, 0008049=male courtship behavior, 0002121=inter-male aggressive behavior" 0016021=integral component of membrane "Ppk23, PPK23, CG8527" "IPR001873=Na+ channel, amiloride-sensitive" CG8527 16-Dec-15 2015_12 "courtship behavior defective,male,behavior defective,recessive,mating behavior defective,viable,fertile" FBgn0052496 CR32496 http://flybase.net/reports/FBgn0052496.html pseudogene_attribute "FBpp0074273, Fibrinogen-related protein, CG32496" CR32496 16-Dec-15 2015_12 WBGene00017013(D1009.3) "ENSMUSG00000033860(Fgg),ENSMUSG00000031594(Fgl1),ENSMUSG00000033831(Fgb),ENSMUSG00000039899(Fgl2),ENSMUSG00000028989(Angptl7),ENSMUSG00000059807(Fga)" "ENSG00000171557(FGG),ENSG00000104760(FGL1),ENSG00000171819(ANGPTL7),ENSG00000127951(FGL2)" FBgn0036075 CG8065 http://flybase.net/reports/FBgn0036075.html protein_coding_gene CG8065 16-Dec-15 2015_12 viable FBgn0027373 RevIII-7b RevIII-7b http://flybase.net/reports/FBgn0027373.html gene 16-Dec-15 2015_12 FBgn0266227 CR44922 http://flybase.net/reports/FBgn0266227.html non_protein_coding_gene lincRNA.670 CR44922 16-Dec-15 2015_12 FBgn0263239 dar1 dendritic arbor reduction 1 http://flybase.net/reports/FBgn0263239.html "FBgn0035454, FBgn0259102, FBgn0016005" protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0007026=negative regulation of microtubule depolymerization, 0050775=positive regulation of dendrite morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "lethal (3) 63Ed, l(3)SH5, CG12029, l(3)63Ed, Dar1" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG12029 16-Dec-15 2015_12 "ENSDARG00000010124(sp5l),ENSDARG00000022517(LOC100329918),ENSDARG00000005846" "YLR131C(ACE2),YDR146C(SWI5)" "ENSMUSG00000072294(Klf12),ENSMUSG00000041649(Klf8),ENSMUSG00000029178(Klf3)" ENSG00000102554(KLF5) FBgn0039303 CG11857 http://flybase.net/reports/FBgn0039303.html protein_coding_gene 0016192=vesicle-mediated transport 0016021=integral component of membrane "IPR004932=Retrieval of early ER protein Rer1, IPR020846=Major facilitator superfamily domain" CG11857 16-Dec-15 2015_12 ENSDARG00000012747(rer1) YCL001W(RER1) WBGene00009783(rer-1) ENSXETG00000027904(rer1) ENSMUSG00000029048(Rer1) ENSG00000157916(RER1) viable DRSC14411 E 0.044100295 0.33729703 2.119432512 -0.146064842 0.015953727 0.090314885 FBgn0260742 CG12213 http://flybase.net/reports/FBgn0260742.html "FBgn0037968, FBgn0015344" protein_coding_gene 0046427=positive regulation of JAK-STAT cascade "87A7-9/3, anon-87Ab" CG12213 16-Dec-15 2015_12 FBgn0262898 CR43253 http://flybase.net/reports/FBgn0262898.html non_protein_coding_gene "lincRNA.596, CG43253" CR43253 16-Dec-15 2015_12 FBgn0035023 ITP Ion transport peptide http://flybase.net/reports/FBgn0035023.html FBgn0046758 protein_coding_gene "0005184=neuropeptide hormone activity, 0005179=hormone activity" "0007218=neuropeptide signaling pathway, 0007623=circadian rhythm, 0046331=lateral inhibition, 0042745=circadian sleep/wake cycle, 0045475=locomotor rhythm" "0005576=extracellular region, 0005615=extracellular space" "DrmITPL1, ion transport peptide, DrmITP, CHH-like, Itp, BcDNA:SD05282, Drm-ITP, ion transport polypeptide, Ion transport peptide, DrmITPL2, chgh, itp, CG13586, ITP" "IPR031098=Arthropod neurohormone/Alpha-latrotoxin associated low molecular weight protein, IPR001166=Arthropod neurohormone, IPR018251=Crustacean neurohormone, conserved site" CG13586 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0267246 CR45686 http://flybase.net/reports/FBgn0267246.html non_protein_coding_gene CR45686 16-Dec-15 2015_12 FBgn0065435 l(2)SH1473 lethal (2) SH1473 http://flybase.net/reports/FBgn0065435.html gene l(2)SH2 1473 16-Dec-15 2015_12 "lethal,recessive" FBgn0051814 CG31814 http://flybase.net/reports/FBgn0051814.html FBgn0028849 protein_coding_gene "31814, BG:DS08249.1" "IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set" CG31814 16-Dec-15 2015_12 "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000024340(Btnl2),ENSMUSG00000053216(Btn2a2)" DRSC01336 IE -2.922077319 -3.235320525 -2.025887636 1.589330465 -0.457304138 1.153801896 FBgn0038460 CG18622 http://flybase.net/reports/FBgn0038460.html FBgn0062955 protein_coding_gene BcDNA:RH18149 CG18622 16-Dec-15 2015_12 viable FBgn0027791 O-fut2 O-fucosyltransferase 2 http://flybase.net/reports/FBgn0027791.html protein_coding_gene "0046922=peptide-O-fucosyltransferase activity, 0008417=fucosyltransferase activity" 0016266=O-glycan processing 0005783=endoplasmic reticulum "OFut2, EG:BACN32G11.6, CG14789, Ofut2, O-fut, O-FUT2" IPR019378=GDP-fucose protein O-fucosyltransferase CG14789 16-Dec-15 2015_12 ENSDARG00000045175(pofut2) WBGene00010757(pad-2) ENSXETG00000018700(POFUT2) ENSMUSG00000020260(Pofut2) ENSG00000186866(POFUT2) "viable,fertile" FBgn0031068 Alr Augmenter of liver regeneration http://flybase.net/reports/FBgn0031068.html protein_coding_gene 0016971=flavin-linked sulfhydryl oxidase activity "0051726=regulation of cell cycle, 0055114=oxidation-reduction process, 0042246=tissue regeneration" 0005739=mitochondrion "alr, augmenter of liver regeneration, CG12534" IPR017905=ERV/ALR sulfhydryl oxidase domain CG12534 16-Dec-15 2015_12 ENSDARG00000070061(gfer) YGR029W(ERV1) WBGene00018955(F56C11.3) ENSXETG00000005771(GFER) ENSMUSG00000040888(Gfer) ENSG00000127554(GFER) "lethal - all die before end of larval stage,recessive,some die during third instar larval stage" imaginal disc FBgn0266622 CR45129 http://flybase.net/reports/FBgn0266622.html non_protein_coding_gene CR45129 16-Dec-15 2015_12 FBgn0002455 mcd microdiscs http://flybase.net/reports/FBgn0002455.html FBgn0004707 gene "l(3)ds11, l(3)1602, l(3)SG8" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc" FBgn0005367 Vc Vortice http://flybase.net/reports/FBgn0005367.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050421 Usp15-31 Ubiquitin specific protease 15/31 http://flybase.net/reports/FBgn0050421.html "FBgn0035054, FBgn0035055" protein_coding_gene 0004843=ubiquitin-specific protease activity "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" "Usp15, CG9189, USP43, CG30421, CG3872, Q9W117, Usp31" "IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site" CG30421 16-Dec-15 2015_12 ENSDARG00000060632(LOC563983) "ENSXETG00000012419(USP31),ENSXETG00000019543(USP43)" ENSMUSG00000020905(Usp43) "ENSG00000103404(USP31),ENSG00000154914(USP43)" "viable,locomotor behavior defective" FBgn0001196 His2A Histone H2A http://flybase.net/reports/FBgn0001196.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0007526=larval somatic muscle development, 0006333=chromatin assembly or disassembly" "0005704=polytene chromosome band, 0000786=nucleosome, 0005700=polytene chromosome, 0005694=chromosome, 0005634=nucleus" "H2A.1, histone H2a, H2A1, dH2A, dH2a, his, histone, histone H2A, H2a, HisC, DmeH2a, Histone2A, Histone, core histone, hist, H2A, H2[[A]], Histone 2A, His2a" "IPR002119=Histone H2A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" 16-Dec-15 2015_12 " adult stage , egg stage | fertilized egg " " spermatozoon

, spermatid | early

, male pronucleus

, spermatid | late

, female pronucleus

" lethal embryonic/larval somatic muscle FBgn0035795 CG16998 http://flybase.net/reports/FBgn0035795.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP104 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG16998 16-Dec-15 2015_12 "ENSXETG00000022959(BC088038.1),ENSXETG00000021647(prtn3),ENSXETG00000021646(BC064208.1),ENSXETG00000008719(BC088027.1)" viable FBgn0039733 CG11504 http://flybase.net/reports/FBgn0039733.html protein_coding_gene IPR006578=MADF domain CG11504 16-Dec-15 2015_12 viable FBgn0060637 l(3)S084308b lethal (3) S084308b http://flybase.net/reports/FBgn0060637.html gene 0843/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0266043 CR44808 http://flybase.net/reports/FBgn0266043.html non_protein_coding_gene CR44808 16-Dec-15 2015_12 FBgn0262027 CR42838 http://flybase.net/reports/FBgn0262027.html pseudogene_attribute CR42838 16-Dec-15 2015_12 FBgn0002508 l(3)SG69 lethal (3) SG69 http://flybase.net/reports/FBgn0002508.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003393 shl shorter legs http://flybase.net/reports/FBgn0003393.html gene 16-Dec-15 2015_12 "visible,male fertile,reduced,viable,male" leg FBgn0039357 CG4743 http://flybase.net/reports/FBgn0039357.html protein_coding_gene "0022857=transmembrane transporter activity, 0000095=S-adenosyl-L-methionine transmembrane transporter activity" "0055085=transmembrane transport, 0015805=S-adenosyl-L-methionine transport, 0006839=mitochondrial transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG4743 16-Dec-15 2015_12 ENSDARG00000058208(slc25a26) YNL003C(PET8) WBGene00008364(D1046.3) ENSXETG00000026858(Q6GLA2_XENTR) ENSMUSG00000045100(Slc25a26) ENSG00000144741(SLC25A26) "viable,fertile" DRSC15636 K 0.281880371 -0.23979025 -0.289919907 -0.325801128 -1.988401405 -0.81444552 FBgn0002423 l(3)F19 lethal (3) F19 http://flybase.net/reports/FBgn0002423.html gene l(3)19 16-Dec-15 2015_12 "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259725 CG42379 http://flybase.net/reports/FBgn0259725.html protein_coding_gene "Dromel_CG9865_FBtr0071680_uorf2, CG9865(uORF2)" CG42379 16-Dec-15 2015_12 FBgn0039244 CG11069 http://flybase.net/reports/FBgn0039244.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0043190=ATP-binding cassette (ABC) transporter complex "IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003593=AAA+ ATPase domain" CG11069 16-Dec-15 2015_12 WBGene00016973(abch-1) ENSG00000138075(ABCG5) FBgn0267501 18SrRNA:CR45841 18S ribosomal RNA:CR45841 http://flybase.net/reports/FBgn0267501.html rRNA_gene CR45841 CR45841 16-Dec-15 2015_12 FBgn0039270 PQBP1 Poly-glutamine tract binding protein 1 http://flybase.net/reports/FBgn0039270.html protein_coding_gene "0008355=olfactory learning, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "PQBP-1, dPQBP-1, CG11820, dPQBP1" IPR001202=WW domain CG11820 16-Dec-15 2015_12 ENSDARG00000029724(pqbp1l) "WBGene00020647(pqbp-1.1),WBGene00020295(pqbp-1.2)" ENSMUSG00000031157(Pqbp1) ENSG00000102103(PQBP1) "viable,fertile,short lived,semidominant,learning defective" DRSC14393 K -1.180289559 -0.355972979 -0.891118449 0.475330872 3.004068797 0.371146393 FBgn0267561 CR45901 http://flybase.net/reports/FBgn0267561.html non_protein_coding_gene CR45901 16-Dec-15 2015_12 FBgn0053733 snmRNA:430:CR33733 snmRNA:430:CR33733 http://flybase.net/reports/FBgn0053733.html non_protein_coding_gene CR33733 CR33733 16-Dec-15 2015_12 FBgn0060551 l(3)S098202b lethal (3) S098202b http://flybase.net/reports/FBgn0060551.html gene 0982/02 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0085317 CG34288 http://flybase.net/reports/FBgn0085317.html protein_coding_gene CG34288 16-Dec-15 2015_12 FBgn0022305 l(1)L35.1 lethal (1) L35.1 http://flybase.net/reports/FBgn0022305.html gene L35.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0034761 CG4250 http://flybase.net/reports/FBgn0034761.html FBgn0062931 protein_coding_gene "BcDNA:RH52355, CT13934" IPR006629=LPS-induced tumour necrosis factor alpha factor CG4250 16-Dec-15 2015_12 WBGene00013604(Y87G2A.18) viable DRSC04455 K 0.909645007 0.028037528 0.751082044 0.047464076 2.021868905 1.167696855 FBgn0000034 AcpK Accessory gland protein K http://flybase.net/reports/FBgn0000034.html gene 16-Dec-15 2015_12 electrophoretic variant FBgn0259307 EP-179 http://flybase.net/reports/FBgn0259307.html gene 16-Dec-15 2015_12 "visible,lethal" "wing,chaeta" FBgn0052074 CG32074 http://flybase.net/reports/FBgn0052074.html protein_coding_gene CG32074 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" DRSC22246 E 0.166899979 -0.004013923 1.536377871 0.445635472 -0.428984842 -1.022940209 FBgn0063643 CE3-3 CE3-3 http://flybase.net/reports/FBgn0063643.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014977 l(1)BP l(1)Brand and Perrimon http://flybase.net/reports/FBgn0014977.html gene GAL4-lethal 16-Dec-15 2015_12 "lethal,recessive" FBgn0020336 anon-65Bb anon-65Bb http://flybase.net/reports/FBgn0020336.html gene "transcript y, y" 16-Dec-15 2015_12 FBgn0266834 CR45296 http://flybase.net/reports/FBgn0266834.html non_protein_coding_gene CR45296 16-Dec-15 2015_12 FBgn0035593 CG4603 http://flybase.net/reports/FBgn0035593.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0016579=protein deubiquitination, 0006520=cellular amino acid metabolic process" "Q9VRJ9, dYOD1" "IPR029071=Ubiquitin-related domain, IPR003323=OTU domain" CG4603 16-Dec-15 2015_12 ENSDARG00000008542(yod1) YFL044C(OTU1) ENSXETG00000017106(YOD1) ENSMUSG00000046404(Yod1) ENSG00000180667(YOD1) "viable,fertile,locomotor behavior defective" FBgn0036992 CG11796 http://flybase.net/reports/FBgn0036992.html protein_coding_gene 0003868=4-hydroxyphenylpyruvate dioxygenase activity "0009072=aromatic amino acid family metabolic process, 0055114=oxidation-reduction process" "IPR004360=Glyoxalase/fosfomycin resistance/dioxygenase domain, IPR029068=Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase, IPR005956=4-hydroxyphenylpyruvate dioxygenase" CG11796 16-Dec-15 2015_12 "ENSDARG00000044935(hpd),ENSDARG00000018351(zgc:56326)" WBGene00001993(hpd-1) ENSXETG00000003766(HPD) ENSMUSG00000029445(Hpd) ENSG00000158104(HPD) viable FBgn0015602 BEAF-32 Boundary element-associated factor of 32kD http://flybase.net/reports/FBgn0015602.html FBgn0013752 protein_coding_gene "0043035=chromatin insulator sequence binding, 0005515=protein binding, 0003677=DNA binding" "0051567=histone H3-K9 methylation, 0048477=oogenesis, 0006325=chromatin organization, 0006357=regulation of transcription from RNA polymerase II promoter" "0005705=polytene chromosome interband, 0000790=nuclear chromatin, 0005634=nucleus" "boundary element associated factor 32, BEAF, BEAF32b, CG10159, Boundary Element Associated Factor of 32, bs04c01.y1, BEAF32B, boundary element-associated factor, Boundary element-associated factor, boundary element associated factor, BEAF-32A, BEAF32, BEAF-32B, Beaf-32, beaf, BEAF32A" "IPR004210=BESS motif, IPR003656=Zinc finger, BED-type" CG10159 16-Dec-15 2015_12 "visible,increased cell death,viable,fertile,lethal,partially,enhancer of variegation,suppressor of variegation,poor,male fertile,female sterile,recessive,maternal effect,dominant,developmental rate defective,large body,lethal - all die before end of larval stage,some die during third instar larval stage" "ommatidium,interommatidial bristle,rhabdomereGMR.PS,eye disc,eye,polytene chromosome | third instar larval stageAB1,polytene chromosome | third instar larval stage34B,X chromosome | male,egg chamber,nurse cell,supernumerary,embryonic/larval fat body,polytene chromosome,imaginal disc,embryonic/larval central nervous system" FBgn0028211 l(3)S011001c lethal (3) S011001c http://flybase.net/reports/FBgn0028211.html gene "0110/01, l(3)S011001" 16-Dec-15 2015_12 "lethal,recessive" FBgn0039195 CG17782 http://flybase.net/reports/FBgn0039195.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG17782 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0023513 CG14803 http://flybase.net/reports/FBgn0023513.html protein_coding_gene 0005515=protein binding "0000724=double-strand break repair via homologous recombination, 0031297=replication fork processing" 0043596=nuclear replication fork EG:63B12.9 "IPR029424=MMS22-like, C-terminal, IPR016024=Armadillo-type fold, IPR029425=Protein MMS22-like, N-terminal" CG14803 16-Dec-15 2015_12 ENSMUSG00000045751(F730047E07Rik) viable FBgn0267898 CR46186 http://flybase.net/reports/FBgn0267898.html pseudogene_attribute ade5-related CR46186 16-Dec-15 2015_12 FBgn0263233 robls54B roadblock similar 54B http://flybase.net/reports/FBgn0263233.html "FBgn0085221, FBgn0028566" protein_coding_gene "GENE 3, CG34192, gene 3, HDC06929" IPR004942=Roadblock/LAMTOR2 domain CG34192 16-Dec-15 2015_12 FBgn0028147 l(3)S045230 lethal (3) S045230 http://flybase.net/reports/FBgn0028147.html gene 0452/30 16-Dec-15 2015_12 "lethal,recessive" FBgn0011616 l(1)I33f3-2 lethal (1) I33f3-2 http://flybase.net/reports/FBgn0011616.html FBgn0010206 gene l(1)33f3 16-Dec-15 2015_12 lethal FBgn0021867 l(2)k13905 lethal (2) k13905 http://flybase.net/reports/FBgn0021867.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266971 CR45422 http://flybase.net/reports/FBgn0266971.html non_protein_coding_gene CR45422 16-Dec-15 2015_12 FBgn0016992 ms(3)1199A ms(3)1199A http://flybase.net/reports/FBgn0016992.html gene 16-Dec-15 2015_12 FBgn0264006 dysc dyschronic http://flybase.net/reports/FBgn0264006.html "FBgn0052132, FBgn0085429, FBgn0043542, FBgn0036384, FBgn0036383, FBgn0052131" protein_coding_gene "0042052=rhabdomere development, 0032414=positive regulation of ion transmembrane transporter activity, 1900074=negative regulation of neuromuscular synaptic transmission, 0072499=photoreceptor cell axon guidance, 0045475=locomotor rhythm, 0046716=muscle cell cellular homeostasis, 0008582=regulation of synaptic growth at neuromuscular junction" 0045202=synapse "CG8760, unnamed, anon-AE003536.1, CG32131, CG32132, Dm_3L:69335, CG17368, CG43749, CG34400" IPR001478=PDZ domain CG43749 16-Dec-15 2015_12 "ENSDARG00000043323(lnx1),ENSDARG00000029177(lnx2a),ENSDARG00000071478(lnx2b)" ENSXETG00000014264(DFNB31) ENSMUSG00000039137(Whrn) ENSG00000095397(DFNB31) FBgn0003543 stu small tumoroid http://flybase.net/reports/FBgn0003543.html gene small tumeroid 16-Dec-15 2015_12 "viable,male,poor,male fertile,visible,melanotic mass phenotype" melanotic mass FBgn0260760 CG42558 http://flybase.net/reports/FBgn0260760.html "FBgn0039725, FBan0007866" protein_coding_gene CG7866 CG42558 16-Dec-15 2015_12 FBgn0034650 NC2ë± Negative Cofactor 2ë± http://flybase.net/reports/FBgn0034650.html protein_coding_gene "0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0043565=sequence-specific DNA binding, 0008134=transcription factor binding, 0046982=protein heterodimerization activity" "0017055=negative regulation of RNA polymerase II transcriptional preinitiation complex assembly, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0017054=negative cofactor 2 complex, 0005622=intracellular" "Nc2alpha, CG10318, dNC2, Drap1, NC2, NC2alpha, dDrap1/dNC2a, dDrap1, dDrap" "IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072=Histone-fold" CG10318 16-Dec-15 2015_12 ENSMUSG00000024914(Drap1) ENSG00000175550(DRAP1) "viable,visible" mesothoracic tergum FBgn0050471 CG30471 http://flybase.net/reports/FBgn0050471.html FBgn0034026 protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" CG8185 "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG30471 16-Dec-15 2015_12 viable FBgn0260606 2L1540 http://flybase.net/reports/FBgn0260606.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0263022 CG43317 http://flybase.net/reports/FBgn0263022.html "FBan0014876, FBgn0038368" protein_coding_gene CG14876 CG43317 16-Dec-15 2015_12 FBgn0036997 CG5955 http://flybase.net/reports/FBgn0036997.html protein_coding_gene "0050662=coenzyme binding, 0003978=UDP-glucose 4-epimerase activity" "IPR016040=NAD(P)-binding domain, IPR001509=NAD-dependent epimerase/dehydratase, N-terminal domain" CG5955 16-Dec-15 2015_12 "ENSDARG00000002745(tdh),ENSDARG00000001463(zgc:165525)" WBGene00017262(F08F3.4) ENSXETG00000000682(TDH) ENSMUSG00000021953(Tdh) "ENSG00000184860(SDR42E1),ENSG00000183921,ENSG00000147383(NSDHL)" "viable,body color defective" mesothoracic tergum FBgn0019687 l(3)LG12 lethal (3) LG12 http://flybase.net/reports/FBgn0019687.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030749 AnxB11 Annexin B11 http://flybase.net/reports/FBgn0030749.html FBgn0046794 protein_coding_gene "0003779=actin binding, 0005509=calcium ion binding, 0005544=calcium-dependent phospholipid binding" "0008360=regulation of cell shape, 0007155=cell adhesion" "AnxB11, Anxb11, annexin B11, BcDNA:GH16395, CG9968, ANXB11, annexin" "IPR001464=Annexin, IPR018502=Annexin repeat, IPR018252=Annexin repeat, conserved site" CG9968 16-Dec-15 2015_12 "ENSDARG00000039645(anxa11a),ENSDARG00000002632" WBGene00003589(nex-2) "ENSXETG00000010645(anxa7),ENSXETG00000018375(anxa11)" "ENSMUSG00000021814(Anxa7),ENSMUSG00000021866(Anxa11)" "ENSG00000138279(ANXA7),ENSG00000122359(ANXA11)" "lethal,viable" FBgn0001382 l(1)2Bn lethal (1) 2Bn http://flybase.net/reports/FBgn0001382.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0031837 DIP-ë_ Dpr-interacting protein ë_ http://flybase.net/reports/FBgn0031837.html protein_coding_gene 0007155=cell adhesion 0005886=plasma membrane "CT31597, 11320, CG11320, DIP-iota" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG11320 16-Dec-15 2015_12 WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" viable FBgn0027121 l(?)A135 lethal (?) A135 http://flybase.net/reports/FBgn0027121.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0031295 CG4375 http://flybase.net/reports/FBgn0031295.html FBgn0061457 protein_coding_gene BcDNA:AT13819 CG4375 16-Dec-15 2015_12 viable FBgn0267481 CR45831 http://flybase.net/reports/FBgn0267481.html non_protein_coding_gene CR45831 16-Dec-15 2015_12 FBgn0014875 Pt8 Protein 8 http://flybase.net/reports/FBgn0014875.html gene 16-Dec-15 2015_12 FBgn0053418 5SrRNA:CR33418 5SrRNA:CR33418 http://flybase.net/reports/FBgn0053418.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33418 CR33418 16-Dec-15 2015_12 FBgn0011863 tRNA:G3:35Bb transfer RNA:gly3:35Bb http://flybase.net/reports/FBgn0011863.html "FBgn0003778, FBgn0051978, FBgn0060219" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR31978, chr2L.trna27-GlyGCC, AE002690.trna18-GlyGCC, tRNA:G:GCC:AE002690-f, tRNA:gly3:35Bb, BG:DS04641.4, tRNA[Gly-GCC]" CR31978 16-Dec-15 2015_12 FBgn0065939 l(2)SH0117 lethal (2) SH0117 http://flybase.net/reports/FBgn0065939.html gene l(2)SH2 0117 16-Dec-15 2015_12 "lethal,recessive" FBgn0019670 mor(1)9 mortality gene (1)9 http://flybase.net/reports/FBgn0019670.html gene 16-Dec-15 2015_12 short lived FBgn0259287 EP-787 http://flybase.net/reports/FBgn0259287.html gene 16-Dec-15 2015_12 visible wing FBgn0040984 CG4440 http://flybase.net/reports/FBgn0040984.html FBgn0047161 protein_coding_gene BcDNA:RE16123 CG4440 16-Dec-15 2015_12 viable DRSC28042 K -0.218650732 0.803158428 0.08515672 -0.358683665 0.631598165 -2.240635291 FBgn0010042 GstD6 Glutathione S transferase D6 http://flybase.net/reports/FBgn0010042.html FBgn0038025 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GSTD6, Gst, GST, DmGST25, Glutathione S transferase D25, gstd6, CG4423, DmGstd6, DmGSTD6, GstD25, gstD25" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG4423 16-Dec-15 2015_12 YNL229C(URE2) adult stage viable FBgn0262610 CG43136 http://flybase.net/reports/FBgn0262610.html protein_coding_gene chrX_5747778_5748511.0 CG43136 16-Dec-15 2015_12 FBgn0032144 CG17633 http://flybase.net/reports/FBgn0032144.html protein_coding_gene "0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" "0006508=proteolysis, 0022008=neurogenesis" 0005615=extracellular space "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG17633 16-Dec-15 2015_12 "WBGene00020281(T06A4.1),WBGene00021213(Y18H1A.9)" "ENSXETG00000016076(CPA3),ENSXETG00000016077(cbp1)" "ENSMUSG00000011463(Cpb1),ENSMUSG00000071553(Cpa2),ENSMUSG00000054446(Cpa1),ENSMUSG00000029788(Cpa5),ENSMUSG00000001865(Cpa3),ENSMUSG00000042501(Cpa6),ENSMUSG00000021999(Cpb2)" "ENSG00000158516(CPA2),ENSG00000091704(CPA1),ENSG00000158525(CPA5),ENSG00000153002(CPB1)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0029857 wuho wuho http://flybase.net/reports/FBgn0029857.html protein_coding_gene "0007283=spermatogenesis, 0036265=RNA (guanine-N7)-methylation, 0048477=oogenesis" "0001673=male germ cell nucleus, 0001674=female germ cell nucleus" "CG15897, wh" "IPR028884=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit, Trm82, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG15897 16-Dec-15 2015_12 WBGene00022420(Y102E9.2) ENSMUSG00000024037(Wdr4) ENSG00000160193(WDR4) "male sterile,female semi-sterile,viable" "ovariole,egg chamber,spermatozoon,mitochondrion & testis,spermatid cyst" FBgn0261920 EndoA::Hsap\TRIP10 http://flybase.net/reports/FBgn0261920.html engineered_fusion_gene endoA::Hsap\TRIP10 16-Dec-15 2015_12 FBgn0266410 CG45050 http://flybase.net/reports/FBgn0266410.html "FBgn0082608, FBgn0053936, FBgn0263749, FBgn0265275, FBgn0025212, FBgn0064858, FBgn0025272, FBgn0053188, FBgn0040535, FBgn0020321, FBgn0053937, FBgn0037681, FBgn0053187, FBtr0082020, FBpp0081498, FBtr0082021, FBpp0081499, FBtr0089839, FBtr0089840, FBpp0088781, FBtr0089841, FBpp0088782" protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" "drn, CG33187, CG33188, anon-EST:fe2G11, CG16751, CG43674, CG3393, CG33937, BcDNA:RE70963, anon-fast-evolving-2G11, anon-EST:fe1B11, CG33936, anon-fast-evolving-1B11, anon-85Da, CG16750" "IPR002653=Zinc finger, A20-type, IPR000058=Zinc finger, AN1-type" CG45050 16-Dec-15 2015_12 FBgn0050383 CG30383 http://flybase.net/reports/FBgn0050383.html "FBtr0088897, FBpp0087971" protein_coding_gene CG30383 16-Dec-15 2015_12 "viable,fertile" FBgn0265612 CR44430 http://flybase.net/reports/FBgn0265612.html non_protein_coding_gene CR44430 16-Dec-15 2015_12 FBgn0265857 CR44646 http://flybase.net/reports/FBgn0265857.html non_protein_coding_gene CR44646 16-Dec-15 2015_12 FBgn0000599 E(var)26A Enhancer of variegation 26A http://flybase.net/reports/FBgn0000599.html gene "E-var(2)1, unnamed, E(var)162" 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0014218 l(2)31Da lethal (2) 31Da http://flybase.net/reports/FBgn0014218.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036908 CG14103 http://flybase.net/reports/FBgn0036908.html protein_coding_gene CG14103 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260286 GSd066 http://flybase.net/reports/FBgn0260286.html gene 16-Dec-15 2015_12 lethal FBgn0259656 B1523 http://flybase.net/reports/FBgn0259656.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263583 CR43608 http://flybase.net/reports/FBgn0263583.html non_protein_coding_gene CR43608 16-Dec-15 2015_12 FBgn0031205 CG12474 http://flybase.net/reports/FBgn0031205.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019789 l(1)14 lethal (1) 14 http://flybase.net/reports/FBgn0019789.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038753 CG4459 http://flybase.net/reports/FBgn0038753.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG4459 16-Dec-15 2015_12 viable FBgn0054010 CG34010 http://flybase.net/reports/FBgn0054010.html FBgn0082884 protein_coding_gene 0008080=N-acetyltransferase activity "BP1022, unnamed" "IPR013653=FR47-like, IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG34010 16-Dec-15 2015_12 "ENSG00000166840(GLYATL1),ENSG00000203972(GLYATL3),ENSG00000156689(GLYATL2),ENSG00000149124(GLYAT)" FBgn0065322 l(2)SH1914 lethal (2) SH1914 http://flybase.net/reports/FBgn0065322.html gene l(2)SH2 1914 16-Dec-15 2015_12 "lethal,recessive" FBgn0036254 CG5645 http://flybase.net/reports/FBgn0036254.html protein_coding_gene "IPR024626=Kri1-like, C-terminal, IPR018034=KRR1 interacting protein 1" CG5645 16-Dec-15 2015_12 ENSDARG00000040522(kri1l) WBGene00010044(F54C9.9) ENSXETG00000011646(KRI1) ENSMUSG00000035047(Kri1) ENSG00000129347(KRI1) "lethal,partially lethal - majority die,visible" trichogen cell DRSC10532 E -0.411041561 -0.150875183 -1.683113587 -0.077360627 -0.258991891 0.017162955 FBgn0265611 CR44429 http://flybase.net/reports/FBgn0265611.html non_protein_coding_gene CR44429 16-Dec-15 2015_12 FBgn0044085 E(rst)H122 E(rst)H122 http://flybase.net/reports/FBgn0044085.html gene 0001745=compound eye morphogenesis H122 16-Dec-15 2015_12 FBgn0021884 l(2)k13403 lethal (2) k13403 http://flybase.net/reports/FBgn0021884.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023133 WppJ White prepupal locus J http://flybase.net/reports/FBgn0023133.html gene "11, 38, 23" 16-Dec-15 2015_12 FBgn0013938 E(sina)3 Enhancer of seven in absentia 3 http://flybase.net/reports/FBgn0013938.html gene 16-Dec-15 2015_12 "lethal,recessive" photoreceptor cell R7 FBgn0033548 CG7637 http://flybase.net/reports/FBgn0033548.html protein_coding_gene 0030515=snoRNA binding "0009267=cellular response to starvation, 0001522=pseudouridine synthesis, 0042254=ribosome biogenesis" 0072588=box H/ACA RNP complex "IPR007264=H/ACA ribonucleoprotein complex, subunit Nop10" CG7637 16-Dec-15 2015_12 ENSDARG00000038187 YHR072W-A(NOP10) WBGene00007708(C25A1.6) ENSXETG00000024771() ENSMUSG00000027133(Nop10) "ENSG00000182117(NOP10),ENSG00000198923" "viable,visible" "mesothoracic tergum,trichogen cell" FBgn0033158 CG12164 http://flybase.net/reports/FBgn0033158.html protein_coding_gene IPR009078=Ferritin-like superfamily CG12164 16-Dec-15 2015_12 "ENSXETG00000006596(),ENSXETG00000010614(),ENSXETG00000000005()" viable FBgn0015822 T-A7.1 T-A7.1 http://flybase.net/reports/FBgn0015822.html gene 16-Dec-15 2015_12 FBgn0024639 l(2)k13217 lethal (2) k13217 http://flybase.net/reports/FBgn0024639.html gene 132/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0034324 CG18538 http://flybase.net/reports/FBgn0034324.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG18538 16-Dec-15 2015_12 viable FBgn0264874 CR44065 http://flybase.net/reports/FBgn0264874.html non_protein_coding_gene CR44065 16-Dec-15 2015_12 FBgn0016816 l(1)L19 lethal (1) L19 http://flybase.net/reports/FBgn0016816.html gene L19 16-Dec-15 2015_12 "lethal,recessive" FBgn0004149 l(2)57Ac lethal (2) 57Ac http://flybase.net/reports/FBgn0004149.html gene 16-Dec-15 2015_12 lethal FBgn0065891 l(2)SH0218 lethal (2) SH0218 http://flybase.net/reports/FBgn0065891.html gene l(2)SH2 0218 16-Dec-15 2015_12 "lethal,recessive" FBgn0085289 CG34260 http://flybase.net/reports/FBgn0085289.html protein_coding_gene "IPR003172=MD-2-related lipid-recognition domain, IPR010512=Protein of unknown function DUF1091, IPR014756=Immunoglobulin E-set" CG34260 16-Dec-15 2015_12 FBgn0013540 l(2)ry51 lethal (2) ry51 http://flybase.net/reports/FBgn0013540.html gene "l(2)51, unnamed" 16-Dec-15 2015_12 lethal FBgn0029030 l(2)R99 lethal (2) R99 http://flybase.net/reports/FBgn0029030.html gene R99 16-Dec-15 2015_12 "lethal,recessive" FBgn0260747 CG5010 http://flybase.net/reports/FBgn0260747.html "FBgn0030821, FBgn0062977, FBgn0017443" protein_coding_gene "0005829=cytosol, 0005654=nucleoplasm" "BcDNA:RE73921, anon-15Dd, transcript f" CG5010 16-Dec-15 2015_12 "ENSDARG00000059304(chchd2l),ENSDARG00000010717(chchd10)" WBGene00007630(har-1) ENSXETG00000010062(chchd2) "ENSMUSG00000070493(Chchd2),ENSMUSG00000049422(Chchd10)" "ENSG00000106153(CHCHD2),ENSG00000186940,ENSG00000138869" FBgn0264820 CR44028 http://flybase.net/reports/FBgn0264820.html pseudogene_attribute CR44028 16-Dec-15 2015_12 FBgn0019970 Indf Indifferent http://flybase.net/reports/FBgn0019970.html gene 16-Dec-15 2015_12 "smell perception defective,dominant,recessive,viable,semidominant" FBgn0036685 CG6664 http://flybase.net/reports/FBgn0036685.html protein_coding_gene IPR019152=Protein of unknown function DUF2046 CG6664 16-Dec-15 2015_12 "ENSDARG00000043334(ccdc6a),ENSDARG00000017595(ccdc6b)" WBGene00011645(T09B9.4) ENSXETG00000003119(CCDC6) ENSMUSG00000048701(Ccdc6) ENSG00000108091(CCDC6) viable FBgn0263954 BG01004 http://flybase.net/reports/FBgn0263954.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0014045 Su(tor)2-187-1 Su(tor)2-187-1 http://flybase.net/reports/FBgn0014045.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0016644 ER3-2 ER3-2 http://flybase.net/reports/FBgn0016644.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260117 2L1629 http://flybase.net/reports/FBgn0260117.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0265687 CR44494 http://flybase.net/reports/FBgn0265687.html non_protein_coding_gene lincRNA.112 CR44494 16-Dec-15 2015_12 FBgn0067331 2D5 2D5 http://flybase.net/reports/FBgn0067331.html gene 0007474=imaginal disc-derived wing vein specification 16-Dec-15 2015_12 "visible,somatic clone,viable" "wing vein,somatic clone" FBgn0052845 CG32845 http://flybase.net/reports/FBgn0052845.html protein_coding_gene 0016853=isomerase activity "IPR023058=Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site, IPR000297=Peptidyl-prolyl cis-trans isomerase, PpiC-type, IPR001202=WW domain" CG32845 16-Dec-15 2015_12 FBgn0084326 Su(dpp)YE28 Su(dpp)YE28 http://flybase.net/reports/FBgn0084326.html gene 16-Dec-15 2015_12 "viable,female sterile" FBgn0022033 l(2)k08708 lethal (2) k08708 http://flybase.net/reports/FBgn0022033.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267632 CR45970 http://flybase.net/reports/FBgn0267632.html non_protein_coding_gene CR45970 16-Dec-15 2015_12 FBgn0010272 Sry-rDM17 Sry-related DM17 http://flybase.net/reports/FBgn0010272.html gene 0003677=DNA binding 0005634=nucleus DM17 16-Dec-15 2015_12 FBgn0085769 CR40728 http://flybase.net/reports/FBgn0085769.html FBan0040728 rRNA_gene CR40728 16-Dec-15 2015_12 FBgn0259315 C143 http://flybase.net/reports/FBgn0259315.html gene 16-Dec-15 2015_12 visible "wing hair,wing vein,wing,chaeta" FBgn0035471 Sc2 Sc2 http://flybase.net/reports/FBgn0035471.html "FBgn0002196, FBgn0010871" protein_coding_gene "0016627=oxidoreductase activity, acting on the CH-CH group of donors" 0006629=lipid metabolic process "0005737=cytoplasm, 0012505=endomembrane system, 0016021=integral component of membrane" "dSc2, lethal(3)63Eb, Ubiquitin-63E, l(3)63Eb, l(3)05634, CG10849, l(3)SH4" "IPR029071=Ubiquitin-related domain, IPR001104=3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal, IPR000626=Ubiquitin domain" CG10849 16-Dec-15 2015_12 "ENSDARG00000070956(tecra),ENSDARG00000039979(zgc:103479)" YDL015C(TSC13) WBGene00000198(art-1) ENSXETG00000020594(gpsn2) ENSMUSG00000031708(Tecr) "ENSG00000099797(TECR),ENSG00000205678(TECRL)" "viable,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259665 B1350 http://flybase.net/reports/FBgn0259665.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment" FBgn0005586 Rab3 Rab3 http://flybase.net/reports/FBgn0005586.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0007269=neurotransmitter secretion, 0032482=Rab protein signal transduction, 0048789=cytoskeletal matrix organization at active zone, 0048790=maintenance of presynaptic active zone structure, 0016192=vesicle-mediated transport, 0015031=protein transport" "0048786=presynaptic active zone, 0045202=synapse, 0008021=synaptic vesicle, 0031982=vesicle" "drab3, rab3, Rab-protein 3, dm-Rab3, DmRab3, CG7576, DRAB3, DRab3, AAF58762, Rab3A, P25228, Drab3" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG7576 16-Dec-15 2015_12 "ENSDARG00000056347(rab3a),ENSDARG00000043835(si:ch211-255d18.4)" WBGene00004267(rab-3) "ENSXETG00000012930(rab3a),ENSXETG00000008055(RAB3B),ENSXETG00000018853(RAB3C)" "ENSMUSG00000031840(Rab3a),ENSMUSG00000021700(Rab3c)" "ENSG00000105649(RAB3A),ENSG00000152932(RAB3C),ENSG00000169213(RAB3B)" " embryonic stage | stage >=13 , embryonic stage -- adult stage , adult stage " " antenno-maxillary complex

, embryonic central nervous system

, cell body &&of adult brain

" "neuroanatomy defective,neurophysiology defective,viable,fertile" "t-bar,neuromuscular junctionED2076)" FBgn0024560 l(3)L5340 lethal (3) L5340 http://flybase.net/reports/FBgn0024560.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085339 CG34310 http://flybase.net/reports/FBgn0085339.html protein_coding_gene CG34310 16-Dec-15 2015_12 FBgn0067102 GlcT-1 Ceramide glucosyltransferase http://flybase.net/reports/FBgn0067102.html FBgn0034690 protein_coding_gene 0008120=ceramide glucosyltransferase activity 0043066=negative regulation of apoptotic process "0000139=Golgi membrane, 0005789=endoplasmic reticulum membrane" "Glucosylceramide synthase, GlcT, GlcT-1, CG6437, ceramide glucosyltransferase, glucosyltransferase, DGlcT-1, dGlcCerT, GlcT1" "IPR025993=Ceramide glucosyltransferase, IPR029044=Nucleotide-diphospho-sugar transferases" CG6437 16-Dec-15 2015_12 ENSDARG00000058221(ugcg) "WBGene00017625(cgt-2),WBGene00019127(cgt-3),WBGene00011517(cgt-1)" ENSXETG00000010219(ugcg) ENSMUSG00000028381(Ugcg) ENSG00000148154(UGCG) "increased cell death,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0065321 l(2)SH1916 lethal (2) SH1916 http://flybase.net/reports/FBgn0065321.html gene l(2)SH2 1916 16-Dec-15 2015_12 "lethal,recessive" FBgn0263484 snoRNA:Pi4KIIë±-a http://flybase.net/reports/FBgn0263484.html snoRNA_gene "snoRNA:Pl4KIIalpha-a, snoRNA:Pi4KIIalpha-a" CR43599 16-Dec-15 2015_12 FBgn0058044 CG40044 http://flybase.net/reports/FBgn0058044.html FBan0040044 protein_coding_gene 16-Dec-15 2015_12 FBgn0264351 CR43807 http://flybase.net/reports/FBgn0264351.html non_protein_coding_gene CR43807 16-Dec-15 2015_12 FBgn0266759 shg::Rnor\CD2::ë±-Cat http://flybase.net/reports/FBgn0266759.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0039943 CG17168 http://flybase.net/reports/FBgn0039943.html FBan0017168 protein_coding_gene "0004864=protein phosphatase inhibitor activity, 0044822=poly(A) RNA binding" "IPR000253=Forkhead-associated (FHA) domain, IPR008984=SMAD/FHA domain" CG17168 16-Dec-15 2015_12 "ENSDARG00000069822(snip1),ENSDARG00000069811" WBGene00016323(C32E8.5) ENSXETG00000017464(snip1) ENSMUSG00000050213(Snip1) ENSG00000163877(SNIP1) DRSC20904 K -0.571545314 0.498556612 -1.031827048 0.103853398 -2.895701975 -1.729738696 FBgn0026162 tRNA:K5:84ABd tRNA:K5:84ABd http://flybase.net/reports/FBgn0026162.html "FBgn0003793, FBgn0011901, FBgn0051490, FBgn0060174" tRNA_gene 0033443=AAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002699.trna8-LysTTT, CR31490, tRNA:K:TTT:AE002699-c, BG:DS00276.4, chr3R.trna2-LysTTT, lys5:84ABd, tRNA:K5" CR31490 16-Dec-15 2015_12 FBgn0037912 sea scheggia http://flybase.net/reports/FBgn0037912.html "FBgn0044763, FBgn0051305, FBtr0089774, FBpp0088715, FBtr0089775, FBpp0088716, FBtr0089776, FBpp0088717, FBtr0089777, FBpp0088718, FBtr0089778, FBpp0088719, FBtr0089779, FBpp0088720, FBtr0089780, FBpp0088721" protein_coding_gene "0022857=transmembrane transporter activity, 0005371=tricarboxylate secondary active transmembrane transporter activity" "0006839=mitochondrial transport, 0015746=citrate transport, 0006843=mitochondrial citrate transport" "0031966=mitochondrial membrane, 0016006=Nebenkern, 0005739=mitochondrion, 0005811=lipid particle" "CG6782, SLC25A1, scheggia, Sea, anon-WO0140519.12, CG31305, l(3)EP3364, sea, DmCIC" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG6782 16-Dec-15 2015_12 "ENSDARG00000063462,ENSDARG00000057110(slc25a1)" YBR291C(CTP1) WBGene00010780(K11H3.3) ENSXETG00000022389(Q6P1T7_XENTR) ENSMUSG00000003528(Slc25a1) ENSG00000100075(SLC25A1) "mitotic cell cycle defective,lethal,viable" "condensed chromosome,embryonic/larval neuroblast,condensed chromosomeMx-1)" FBgn0004750 l(3)89Bc lethal (3) 89Bc http://flybase.net/reports/FBgn0004750.html gene 16-Dec-15 2015_12 lethal FBgn0033019 CG10395 http://flybase.net/reports/FBgn0033019.html FBan0010395 protein_coding_gene "0006355=regulation of transcription, DNA-templated, 0006338=chromatin remodeling" 0031011=Ino80 complex mdcds_12730 "IPR029523=INO80 complex, subunit Ies2, IPR006880=INO80 complex subunit B-like conserved region, IPR007529=Zinc finger, HIT-type" CG10395 16-Dec-15 2015_12 ENSDARG00000062749(zgc:153347) ENSMUSG00000030034(Ino80b) ENSG00000221956 "viable,body color defective" mesothoracic tergum FBgn0011866 tRNA:G3:35Be transfer RNA:gly3:35Be http://flybase.net/reports/FBgn0011866.html "FBgn0003779, FBgn0051980, FBgn0060222" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002690.trna15-GlyGCC, CR31980, tRNA[Gly-GCC], tRNA:G:GCC:AE002690-c, BG:DS04641.7, chr2L.trna24-GlyGCC, tRNA:gly3:35Be" CR31980 16-Dec-15 2015_12 FBgn0066348 l(3)99DEg lethal (3) 99DEg http://flybase.net/reports/FBgn0066348.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263497 CR43486 http://flybase.net/reports/FBgn0263497.html non_protein_coding_gene lincRNA.695 CR43486 16-Dec-15 2015_12 FBgn0259831 CG34309 http://flybase.net/reports/FBgn0259831.html "FBgn0085338, FBgn0040552" protein_coding_gene "Dm_3R:49681, Dm_3R:49679, CG14378" CG34309 16-Dec-15 2015_12 viable FBgn0010013 Canp Ca2+-activated neutral protease http://flybase.net/reports/FBgn0010013.html gene 0004198=calcium-dependent cysteine-type endopeptidase activity "Ca[2+] activated thioprotease, Ca-TPase, nCAPII, CANP" 16-Dec-15 2015_12 FBgn0051776 CG31776 http://flybase.net/reports/FBgn0051776.html "FBgn0031541, FBgn0063621" protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process 0005795=Golgi stack "CG8845a, dppGalNAcT10, CG8845" "IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain, IPR029044=Nucleotide-diphospho-sugar transferases" CG31776 16-Dec-15 2015_12 viable FBgn0032670 CG5783 http://flybase.net/reports/FBgn0032670.html protein_coding_gene 0008080=N-acetyltransferase activity "IPR016181=Acyl-CoA N-acyltransferase, IPR013653=FR47-like, IPR000182=GNAT domain" CG5783 16-Dec-15 2015_12 ENSDARG00000051954(LOC799646) "ENSG00000166840(GLYATL1),ENSG00000203972(GLYATL3),ENSG00000156689(GLYATL2),ENSG00000149124(GLYAT)" viable FBgn0053911 CG33911 http://flybase.net/reports/FBgn0053911.html FBgn0028861 protein_coding_gene "DS07295.4, BG:DS07295.4" 16-Dec-15 2015_12 FBgn0266277 CR44962 http://flybase.net/reports/FBgn0266277.html non_protein_coding_gene CR44962 16-Dec-15 2015_12 FBgn0039437 TwdlL TweedleL http://flybase.net/reports/FBgn0039437.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix "TwdIL, CG6447" IPR004145=Domain of unknown function DUF243 CG6447 16-Dec-15 2015_12 FBgn0022313 l(1)H22.1 lethal (1) H22.1 http://flybase.net/reports/FBgn0022313.html gene H22.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0040742 CG15606 http://flybase.net/reports/FBgn0040742.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031331 CG5440 http://flybase.net/reports/FBgn0031331.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0000209=protein polyubiquitination "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2, IPR023313=Ubiquitin-conjugating enzyme, active site" CG5440 16-Dec-15 2015_12 FBgn0003277 RpII215 RNA polymerase II 215kD subunit http://flybase.net/reports/FBgn0003277.html "FBgn0001616, FBgn0026704" protein_coding_gene "0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity" "0006366=transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint" "0005634=nucleus, 0005665=DNA-directed RNA polymerase II, core complex, 0005700=polytene chromosome, 0005703=polytene chromosome puff" "Pol II0[ser5], CG1554, RNApolII, l(1)DF912, 5, Pol II Ser5P, dRpb1, PolIIo[ser2], RNAP II, Pol II large subunit, dRPB1, RNAPII0, RPII215, RNAP, l(1)10Ca, H5, 8WG16, RNAP II LS, Pol IIo, Pol IIo[Ser2], RNA PolII, Pol-IIa, RPB1, Pol II large subunit CTD, RNApol, Pol II, IIo, PolIIo, RNA pol II, alphaPol IIo[ser2], II, RNA PolI 215, L5, RNApol2, RNA pol IIo, Ubl, Rpb1, RNA Pol II, Pol II CTD, RNA polymerase II large subunit, Pol II0[ser2], PolIIa, rpII1, Pol IIo[ser2], pol II, Pol IIa, Pol IIo[ser5], polII, Ser5-P Pol II, RNA-PolII, Rpll215, RNA Polymerase II, RNA polymerase IIo, Ultrabithorax-like, RNA Pol II CTD, RpII, RNAPII, RNA polymeraseII-215 kd subunit, RNA polII, CTD, l(1)L5, polymerase II CTD, PolIIo[ser5], RNA-polymerase II, PolII, RNA polymerase II, Pol II[ser2], l(1)DC912, POL, l(1)G0040, Pol II Ser5p" "IPR000722=RNA polymerase, alpha subunit, IPR000684=RNA polymerase II, heptapeptide repeat, eukaryotic, IPR007080=RNA polymerase Rpb1, domain 1, IPR007081=RNA polymerase Rpb1, domain 5, IPR007083=RNA polymerase Rpb1, domain 4, IPR007075=RNA polymerase Rpb1, domain 6, IPR007066=RNA polymerase Rpb1, domain 3, IPR007073=RNA polymerase Rpb1, domain 7, IPR006592=RNA polymerase, N-terminal" CG1554 16-Dec-15 2015_12 ENSDARG00000055174(LOC100334761) YDL140C(RPO21) WBGene00000123(ama-1) ENSMUSG00000005198(Polr2a) ENSG00000181222(SLC35G6) "lethal,recessive,heat sensitive,viable,visible,dominant,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical resistant,female sterile,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,male fertile,partially,cell lethal,germline clone,male sterile,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "capitellum,ovariole,germline clone,oocyte,prothoracic tarsal segment 2,male,haltere" DRSC20280 EK -0.264436424 0.311638996 1.50902253 -2.929978114 1.809341559 5.322892763 FBgn0028243 l(3)S000721 lethal (3) S000721 http://flybase.net/reports/FBgn0028243.html gene 21-Jul 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0000077 amx almondex http://flybase.net/reports/FBgn0000077.html FBgn0028503 protein_coding_gene "0007498=mesoderm development, 0007220=Notch receptor processing, 0001713=ectodermal cell fate determination, 0045747=positive regulation of Notch signaling pathway, 0007398=ectoderm development, 0046331=lateral inhibition" 0044214=spanning component of plasma membrane "fs(1)amx, CG12127, BcDNA:GH02974" IPR007829=TM2 domain CG12127 16-Dec-15 2015_12 WBGene00016567(C41D11.9) ENSXETG00000026576(TM2D3) ENSMUSG00000078681(Tm2d3) ENSG00000184277(TM2D3) "viable,fertile,lethal - all die before end of embryonic stage,neurogenic phenotype,some die during embryonic stage,visible,recessive,lethal,rescuable maternal effect,female sterile,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "eye,epidermis,nervous system,ommatidium,thorax,rescuable maternal effect,ectoderm,embryonic epidermis,sensory mother cell,neuroblast,maternal effect,supernumerary" FBgn0000236 bu bulging http://flybase.net/reports/FBgn0000236.html gene 16-Dec-15 2015_12 "visible,recessive,partially lethal - majority die" eye FBgn0001245 hypoG hypoactive G http://flybase.net/reports/FBgn0001245.html gene 16-Dec-15 2015_12 "hypoactive,optomotor response defective,locomotor behavior defective,flight defective" FBgn0037082 CG5664 http://flybase.net/reports/FBgn0037082.html protein_coding_gene CG5664 16-Dec-15 2015_12 viable FBgn0032020 CG7787 http://flybase.net/reports/FBgn0032020.html FBgn0064882 protein_coding_gene "0008270=zinc ion binding, 0005085=guanyl-nucleotide exchange factor activity" 0007264=small GTPase mediated signal transduction "0005829=cytosol, 0016020=membrane" BcDNA:RE45155 "IPR007515=Mss4, IPR011323=Mss4/translationally controlled tumour-associated TCTP, IPR011057=Mss4-like" CG7787 16-Dec-15 2015_12 "ENSDARG00000002690(rabif),ENSDARG00000070564" WBGene00014938(mdt-9) ENSXETG00000025908(RABIF) ENSMUSG00000042229(Rabif) ENSG00000183155(RABIF) "partially lethal - majority die,some die during pupal stage" FBgn0015950 hsk helter-skelter http://flybase.net/reports/FBgn0015950.html gene 16-Dec-15 2015_12 "viable,female sterile" embryonic/larval brain FBgn0028045 l(3)S097001 lethal (3) S097001 http://flybase.net/reports/FBgn0028045.html FBgn0060492 gene "l(3)S108709, 1450/06, 1087/09, 0970/01" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0069149 mcl(3)Z3426 mcl(3)Z3426 http://flybase.net/reports/FBgn0069149.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0033712 CG13163 http://flybase.net/reports/FBgn0033712.html protein_coding_gene 0003743=translation initiation factor activity 0006413=translational initiation "IPR001288=Translation initiation factor 3, IPR019815=Translation initiation factor 3, C-terminal" CG13163 16-Dec-15 2015_12 viable FBgn0028611 l(2)W14 lethal (2) W14 http://flybase.net/reports/FBgn0028611.html gene l(2R)W14 16-Dec-15 2015_12 "lethal,recessive" FBgn0053736 snmRNA:430:CR33736 snmRNA:430:CR33736 http://flybase.net/reports/FBgn0053736.html non_protein_coding_gene CR33736 CR33736 16-Dec-15 2015_12 FBgn0263240 Coop Corepressor of Pangolin http://flybase.net/reports/FBgn0263240.html "FBgn0259124, FBgn0033182" protein_coding_gene "0008134=transcription factor binding, 0001106=RNA polymerase II transcription corepressor activity, 0003677=DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0030178=negative regulation of Wnt signaling pathway" "0005634=nucleus, 0005667=transcription factor complex" "co-repressor of Pangolin, Co-repressor of Pangolin, coop, corepressor of Pan, CG1621" "IPR004210=BESS motif, IPR006578=MADF domain" CG1621 16-Dec-15 2015_12 FBgn0001255 ImpE3 Ecdysone-inducible gene E3 http://flybase.net/reports/FBgn0001255.html "FBgn0037542, FBgn0040525" protein_coding_gene 0007561=imaginal disc eversion "0019898=extrinsic component of membrane, 0005886=plasma membrane" "IMP-E3, Imp-E3, CG11046, CG2723" CG2723 16-Dec-15 2015_12 "viable,fertile" DRSC16716 IE 1.217114555 2.211865468 -0.711556829 1.843291439 0.066562464 0.954554432 FBgn0069441 E(zip)18-5 E(zip)18-5 http://flybase.net/reports/FBgn0069441.html gene 18-5 16-Dec-15 2015_12 "lethal,recessive" FBgn0260283 GSd322 http://flybase.net/reports/FBgn0260283.html gene 16-Dec-15 2015_12 lethal FBgn0033990 CG10265 http://flybase.net/reports/FBgn0033990.html "FBgn0050475, FBgn0050474" protein_coding_gene CG30474 CG10265 16-Dec-15 2015_12 viable DRSC05986 E -0.442621924 -0.052328941 0.469293004 1.514876172 -0.362199737 -0.51456077 FBgn0034730 ppk12 pickpocket 12 http://flybase.net/reports/FBgn0034730.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "PPK12, CG10972" "IPR001873=Na+ channel, amiloride-sensitive" CG10972 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" WBGene00022815(asic-1) "ENSXETG00000001026(),ENSXETG00000018954(scnn1a)" "ENSMUSG00000020704(Accn1),ENSMUSG00000023017(Accn2),ENSMUSG00000038276(Accn3),ENSMUSG00000033007(Accn4),ENSMUSG00000028008(Accn5)" "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" viable DRSC04086 I -0.497343513 -1.795308451 -0.956148973 0.645294904 0.25377 -0.702192321 FBgn0067751 l(1)G0189 lethal (1) G0189 http://flybase.net/reports/FBgn0067751.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0083009 snoRNA:ë¬28S-1135d snoRNA:ë¬28S-1135d http://flybase.net/reports/FBgn0083009.html snoRNA_gene "Psi28S-1135d, psi28S-1135d, CR34603" CR34603 16-Dec-15 2015_12 FBgn0019798 l(1)07 lethal (1) 07 http://flybase.net/reports/FBgn0019798.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015263 Mst23Ea Male-specific transcript 23Ea http://flybase.net/reports/FBgn0015263.html gene 16-Dec-15 2015_12 FBgn0083085 kur kur http://flybase.net/reports/FBgn0083085.html gene "Kurzkern, kurzkern" 16-Dec-15 2015_12 "nucleus | gastrula stage,nucleus | blastoderm stage" FBgn0267759 CR46090 http://flybase.net/reports/FBgn0267759.html non_protein_coding_gene CR46090 16-Dec-15 2015_12 FBgn0038414 CG6901 http://flybase.net/reports/FBgn0038414.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG6901 16-Dec-15 2015_12 viable FBgn0267642 CR45980 http://flybase.net/reports/FBgn0267642.html non_protein_coding_gene CR45980 16-Dec-15 2015_12 FBgn0043981 Su(rst)G67 Su(rst)G67 http://flybase.net/reports/FBgn0043981.html gene 0001745=compound eye morphogenesis G67 16-Dec-15 2015_12 viable FBgn0039056 CenB1A Centaurin beta 1A http://flybase.net/reports/FBgn0039056.html protein_coding_gene "0005543=phospholipid binding, 0005096=GTPase activator activity" "0006909=phagocytosis, 0043087=regulation of GTPase activity, 0000902=cell morphogenesis" "Cen1ba, CG6742, CenB1A, cenB1A, centaurin beta 1A" "IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR001164=Arf GTPase activating protein" CG6742 16-Dec-15 2015_12 "ENSDARG00000060783,ENSDARG00000056346(zgc:153917),ENSDARG00000056478(LOC564814),ENSDARG00000018234" WBGene00000565(cnt-1) "ENSXETG00000001021(ACAP3),ENSXETG00000003455(ACAP2)" "ENSMUSG00000029033(Acap3),ENSMUSG00000049076(Acap2),ENSMUSG00000001588(Acap1)" "ENSG00000114331(ACAP2),ENSG00000131584(ACAP3),ENSG00000072818(ACAP1)" "viable,visible" trichogen cell FBgn0266596 CR45121 http://flybase.net/reports/FBgn0266596.html non_protein_coding_gene CR45121 16-Dec-15 2015_12 FBgn0060497 l(3)S107705b lethal (3) S107705b http://flybase.net/reports/FBgn0060497.html gene 1077/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0083091 fermata fermata http://flybase.net/reports/FBgn0083091.html gene "0007111=meiosis II cytokinesis, 0007110=meiosis I cytokinesis" fer 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern" FBgn0002405 l(3)99Df lethal (3) 99Df http://flybase.net/reports/FBgn0002405.html gene 16-Dec-15 2015_12 lethal FBgn0037017 CG4074 http://flybase.net/reports/FBgn0037017.html protein_coding_gene 0008565=protein transporter activity "0042147=retrograde transport, endosome to Golgi" "0030906=retromer complex, inner shell, 0005768=endosome" "DmDSCR3, DSCR3" IPR028934=Vacuolar protein sorting protein 26 related CG4074 16-Dec-15 2015_12 ENSXETG00000013035(DSCR3) ENSMUSG00000022898(Dscr3) ENSG00000157538(DSCR3) "viable,fertile" FBgn0032404 RpL7-like Ribosomal protein L7-like http://flybase.net/reports/FBgn0032404.html protein_coding_gene 0003735=structural constituent of ribosome "0022008=neurogenesis, 0006412=translation" 0022625=cytosolic large ribosomal subunit CG5317 "IPR005998=Ribosomal protein L7, eukaryotic, IPR016082=Ribosomal protein L30, ferredoxin-like fold domain" CG5317 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,embryonic/larval salivary gland" FBgn0264311 l(2)k14501 http://flybase.net/reports/FBgn0264311.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005288 mei-1946 meiotic 1946 http://flybase.net/reports/FBgn0005288.html gene 1946 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0005251 l(3)R350 lethal of Roberts 350 http://flybase.net/reports/FBgn0005251.html gene l(3)350 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0037205 BoYb Brother of Yb http://flybase.net/reports/FBgn0037205.html protein_coding_gene "0010526=negative regulation of transposition, RNA-mediated" 0070725=Yb body "brother of Yb, CG11133" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG11133 16-Dec-15 2015_12 "female semi-sterile,female fertile" FBgn0032465 CG12404 http://flybase.net/reports/FBgn0032465.html protein_coding_gene 0007283=spermatogenesis 0000139=Golgi membrane IPR006977=Yip1 domain CG12404 16-Dec-15 2015_12 "ENSDARG00000007279(zgc:56513),ENSDARG00000039726(zgc:123321)" YGR172C(YIP1) WBGene00009336(F32D8.14) ENSXETG00000005469(yipf5) "ENSMUSG00000029158(Yipf7),ENSMUSG00000024487(Yipf5)" ENSG00000145817(YIPF5) lethal FBgn0265763 CR44570 http://flybase.net/reports/FBgn0265763.html non_protein_coding_gene CR44570 16-Dec-15 2015_12 FBgn0260268 GSd450 http://flybase.net/reports/FBgn0260268.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve,segmental nerve" FBgn0044001 Su(rst)C379 Su(rst)C379 http://flybase.net/reports/FBgn0044001.html gene 0001745=compound eye morphogenesis C379 16-Dec-15 2015_12 FBgn0040466 Dlip2 Dorsal interacting protein 2 http://flybase.net/reports/FBgn0040466.html FBgn0037264 protein_coding_gene "0005515=protein binding, 0003676=nucleic acid binding" "CG9771, DIP2, Dip2, dip2, septin interacting protein 4, dmDIP2, sip4, dorsal interacting protein 2" "IPR006612=Zinc finger, C2CH-type" CG9771 16-Dec-15 2015_12 "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0060900 l(3)S044205b lethal (3) S044205b http://flybase.net/reports/FBgn0060900.html gene 0442/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0085291 CR34262 http://flybase.net/reports/FBgn0085291.html pseudogene_attribute CR34262 16-Dec-15 2015_12 FBgn0024268 acd(2)5D10 auditory courtship defective 5D10 http://flybase.net/reports/FBgn0024268.html gene "0008049=male courtship behavior, 0031223=auditory behavior" "5D10, unnamed" 16-Dec-15 2015_12 "viable,auditory perception defective,touch sensitivity defective" FBgn0040100 lectin-24Fb lectin-24Fb http://flybase.net/reports/FBgn0040100.html gene 0005534=galactose binding "AC004373b, unnamed, AC 004373B" 16-Dec-15 2015_12 FBgn0033789 CG13324 http://flybase.net/reports/FBgn0033789.html protein_coding_gene CG13324 16-Dec-15 2015_12 viable FBgn0085748 CR40573 http://flybase.net/reports/FBgn0085748.html FBan0040573 rRNA_gene CR40573 16-Dec-15 2015_12 FBgn0000837 fs(1)M21 female sterile (1) M21 http://flybase.net/reports/FBgn0000837.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0030347 CG15739 http://flybase.net/reports/FBgn0030347.html protein_coding_gene "0016791=phosphatase activity, 0004035=alkaline phosphatase activity, 0004721=phosphoprotein phosphatase activity" 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" "17945012, FPPase, Phos15739" "IPR023215=Nitrophenylphosphatase-like domain, IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR023214=HAD-like domain" CG15739 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039642 CG11882 http://flybase.net/reports/FBgn0039642.html protein_coding_gene IPR028043=Protein of unknown function DUF4506 CG11882 16-Dec-15 2015_12 viable FBgn0259272 C800 http://flybase.net/reports/FBgn0259272.html gene 16-Dec-15 2015_12 "visible,lethal" wing FBgn0278597 CR46267 http://flybase.net/reports/FBgn0278597.html non_protein_coding_gene CR46267 16-Dec-15 2015_12 FBgn0027627 qed qed http://flybase.net/reports/FBgn0027627.html gene 16-Dec-15 2015_12 visible "eye,ventral,maxillary palpus" FBgn0267057 CR45501 http://flybase.net/reports/FBgn0267057.html non_protein_coding_gene CR45501 16-Dec-15 2015_12 FBgn0042695 Nuk Nuk http://flybase.net/reports/FBgn0042695.html gene Dnuk 16-Dec-15 2015_12 FBgn0027203 l(1)G0423 lethal (1) G0423 http://flybase.net/reports/FBgn0027203.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0028912 tRNA:P:35Ba tRNA:P:35Ba http://flybase.net/reports/FBgn0028912.html "FBgn0051983, FBgn0060122" tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:pro, CR31983, BG:DS01486.2, chr2L.trna20-ProAGG, tRNA:P:AGG:AE002690-b, AE002690.trna11-ProAGG" CR31983 16-Dec-15 2015_12 FBgn0058346 CG40346 http://flybase.net/reports/FBgn0058346.html FBan0040346 protein_coding_gene 16-Dec-15 2015_12 FBgn0011233 tho thousand points of light http://flybase.net/reports/FBgn0011233.html gene "0007286=spermatid development, 0007283=spermatogenesis" "ms(3)04112, tho86E" 16-Dec-15 2015_12 "male sterile,recessive,partially lethal - majority die" "spermatozoon,spermatid & nucleus,primary spermatocyte cyst,spermatid" FBgn0264358 CR43810 http://flybase.net/reports/FBgn0264358.html non_protein_coding_gene CR43810 16-Dec-15 2015_12 FBgn0000096 ants antennas http://flybase.net/reports/FBgn0000096.html gene Ants 16-Dec-15 2015_12 "viable,good,visible,recessive" antenna FBgn0013755 Bro Brother http://flybase.net/reports/FBgn0013755.html protein_coding_gene "0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0003713=transcription coactivator activity" "0035206=regulation of hemocyte proliferation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0016513=core-binding factor complex" "Beta for Runt and OTHERs, runt domain partner beta1, bro, CG7960, rpbeta1" "IPR003417=Core binding factor, beta subunit" CG7960 16-Dec-15 2015_12 ENSDARG00000040917(cbfb) ENSXETG00000020027(CBFB) ENSMUSG00000031885(Cbfb) ENSG00000067955(CBFB) embryonic stage

ubiquitous "viable,fertile" embryonic/first instar larval cuticle FBgn0000957 fs(2)E4 female sterile (2) E4 http://flybase.net/reports/FBgn0000957.html gene fs2.4 16-Dec-15 2015_12 "female sterile,recessive" "female reproductive system,egg" FBgn0264518 CR43917 http://flybase.net/reports/FBgn0264518.html non_protein_coding_gene lincRNA.429 CR43917 16-Dec-15 2015_12 FBgn0021777 md1 muscle disorganised 1 http://flybase.net/reports/FBgn0021777.html gene 16-Dec-15 2015_12 FBgn0061435 CG30270 http://flybase.net/reports/FBgn0061435.html FBgn0050270 protein_coding_gene BcDNA:AT30770 CG30270 16-Dec-15 2015_12 DRSC22890 I 1.190272924 -1.629845329 0.23415512 -0.059303735 0.134884508 -0.039804856 FBgn0035427 ckd cracked http://flybase.net/reports/FBgn0035427.html "FBgn0062428, FBgn0062642, FBgn0062665" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "BcDNA:RH52423, cracked, CKD, EP3139, EP714, ckd, EP(3)0714, CG14959, EP(2)3139" IPR002557=Chitin binding domain CG14959 16-Dec-15 2015_12 "viable,fertile,visible" eye FBgn0027976 l(3)S139308b lethal (3) S139308b http://flybase.net/reports/FBgn0027976.html gene "1393/08, l(3)S139308" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0031545 CG3213 http://flybase.net/reports/FBgn0031545.html protein_coding_gene bs30c03.y1 CG3213 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC00576 IEK 1.658188609 0.394044859 1.857874755 1.53639671 2.666516006 3.669221064 FBgn0032051 CG13097 http://flybase.net/reports/FBgn0032051.html protein_coding_gene "0006364=rRNA processing, 0009267=cellular response to starvation" "0005732=small nucleolar ribonucleoprotein complex, 0034457=Mpp10 complex" "IPR012173=U3 small nucleolar ribonucleoprotein complex, subunit Mpp10" CG13097 16-Dec-15 2015_12 ENSDARG00000012495(mphosph10) YJR002W(MPP10) WBGene00013544(Y75B8A.7) ENSXETG00000016497() ENSMUSG00000030521(Mphosph10) ENSG00000124383(MPHOSPH10) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085306 CG34277 http://flybase.net/reports/FBgn0085306.html protein_coding_gene CG34277 16-Dec-15 2015_12 FBgn0058329 CG40329 http://flybase.net/reports/FBgn0058329.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019782 l(1)24 lethal (1) 24 http://flybase.net/reports/FBgn0019782.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021770 nori-1 nori-1 http://flybase.net/reports/FBgn0021770.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0010901 l(3)06743 lethal (3) 06743 http://flybase.net/reports/FBgn0010901.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083314 E(smoDN)1333 Enhancer of smoDN 1333 http://flybase.net/reports/FBgn0083314.html gene 16-Dec-15 2015_12 FBgn0051902 Spn28Da Serpin 28Da http://flybase.net/reports/FBgn0051902.html FBgn0031964 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0032504=multicellular organism reproduction, 0045861=negative regulation of proteolysis" 0005615=extracellular space "CG12318, CG31902" "IPR000215=Serpin family, IPR023795=Serpin, conserved site, IPR023796=Serpin domain" CG31902 16-Dec-15 2015_12 ENSDARG00000034168(serpini1) "ENSXETG00000027588(serpinb6),ENSXETG00000027590(BC087996.1),ENSXETG00000025592()" "ENSG00000206073(SERPINB4),ENSG00000057149(SERPINB3),ENSG00000197641(SERPINB13),ENSG00000166634(SERPINB12),ENSG00000166396(SERPINB7),ENSG00000117601(SERPINC1)" FBgn0264715 CR43983 http://flybase.net/reports/FBgn0264715.html non_protein_coding_gene CR43983 16-Dec-15 2015_12 FBgn0261507 CG42655 http://flybase.net/reports/FBgn0261507.html protein_coding_gene CG42655 16-Dec-15 2015_12 FBgn0050052 Obp49a Odorant-binding protein 49a http://flybase.net/reports/FBgn0050052.html "FBgn0033768, FBgn0063220" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG30052, obp49a, DmelObp49a, CG8769, Obp49A, BcDNA:GH25962" IPR006170=Pheromone/general odorant binding protein CG30052 16-Dec-15 2015_12 "chemosensitive behavior defective,viable,visible" "trichogen cell,mesothoracic tergum" FBgn0262607 CG43133 http://flybase.net/reports/FBgn0262607.html protein_coding_gene CG43133 16-Dec-15 2015_12 FBgn0069992 BG01891 BG01891 http://flybase.net/reports/FBgn0069992.html gene 16-Dec-15 2015_12 stress response defective FBgn0034141 CG8311 http://flybase.net/reports/FBgn0034141.html protein_coding_gene 0004168=dolichol kinase activity 0043048=dolichyl monophosphate biosynthetic process 0030176=integral component of endoplasmic reticulum membrane dolichol kinase IPR026566=Dolichol kinase CG8311 16-Dec-15 2015_12 YMR013C(SEC59) ENSXETG00000024754(DOLK) ENSMUSG00000075419(Dolk) ENSG00000175283(DOLK) viable FBgn0032791 CG18094 http://flybase.net/reports/FBgn0032791.html FBgn0032792 protein_coding_gene 0016787=hydrolase activity CG10048 "IPR000086=NUDIX hydrolase domain, IPR015797=NUDIX hydrolase domain-like" CG18094 16-Dec-15 2015_12 WBGene00003584(ndx-7) FBgn0012018 tRNA:Y1:28C transfer RNA:tyr1:28C http://flybase.net/reports/FBgn0012018.html "FBgn0012014, FBgn0051905" tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:tyr1:28C, tRNA-Tyr, tRNA[Tyr], Tyr-tRNA, tRNA[Tyr][[1gamma]], tRNA:Y, CR31905" CR31905 16-Dec-15 2015_12 FBgn0004764 l(3)89Da lethal (3) 89Da http://flybase.net/reports/FBgn0004764.html gene 16-Dec-15 2015_12 lethal FBgn0266011 CR44784 http://flybase.net/reports/FBgn0266011.html non_protein_coding_gene CR44784 16-Dec-15 2015_12 FBgn0013939 E(sina)4 Enhancer of seven in absentia 4 http://flybase.net/reports/FBgn0013939.html gene 16-Dec-15 2015_12 "lethal,recessive" "photoreceptor cell R7,secondary pigment cell" FBgn0265373 CG44314 http://flybase.net/reports/FBgn0265373.html protein_coding_gene CG44314 16-Dec-15 2015_12 FBgn0264078 Flo2 Flotillin 2 http://flybase.net/reports/FBgn0264078.html "FBgn0024753, FBgn0030585, FBgn0052593, FBgn0027942" protein_coding_gene 0005198=structural molecule activity "0035011=melanotic encapsulation of foreign target, 0007155=cell adhesion" "0005886=plasma membrane, 0016600=flotillin complex, 0005829=cytosol, 0005737=cytoplasm" "flotillin 2, reggie1, Flotillin-2, mdcds_54791, flotillin, Flotillin 2, FLO2, Flo-2, DmFlo2, CG11547, CG14409, flo2, flotillin2, Flotillin2, flottilin 2, CG32593, Flo, reggie-1, Flo2, FLO[Dm]-2, flotillin-2" "IPR027705=Flotillin family, IPR001107=Band 7 protein" CG32593 16-Dec-15 2015_12 "ENSDARG00000004830(flot2a),ENSDARG00000069774(zgc:64103)" "ENSXETG00000014349(flot2),ENSXETG00000022137()" ENSMUSG00000061981(Flot2) ENSG00000132589(FLOT2) FBgn0085782 CR41101 http://flybase.net/reports/FBgn0085782.html FBan0041101 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0013460 fs(3)302 fs(3)302 http://flybase.net/reports/FBgn0013460.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive,female sterile,male sterile" FBgn0020348 anon-46Fa anon-46Fa http://flybase.net/reports/FBgn0020348.html gene "unnamed, 6H8" 16-Dec-15 2015_12 FBgn0069932 CG41119 http://flybase.net/reports/FBgn0069932.html protein_coding_gene 16-Dec-15 2015_12 FBgn0283428 CR46271 http://flybase.net/reports/FBgn0283428.html non_protein_coding_gene CR46271 16-Dec-15 2015_12 FBgn0060913 l(3)S042805b lethal (3) S042805b http://flybase.net/reports/FBgn0060913.html gene 0428/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0058374 CG40374 http://flybase.net/reports/FBgn0058374.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030006 CG17982 http://flybase.net/reports/FBgn0030006.html protein_coding_gene CG17982 16-Dec-15 2015_12 viable FBgn0003156 pt platinum http://flybase.net/reports/FBgn0003156.html gene "fs(1)M47, l(1)VA70, l(1)7Fb, pa" 16-Dec-15 2015_12 "lethal,female sterile,rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,male sterile,male,poor,body color defective" "egg,macrochaeta" FBgn0011573 Cdc37 Cdc37 http://flybase.net/reports/FBgn0011573.html FBgn0004640 protein_coding_gene "0051087=chaperone binding, 0019901=protein kinase binding, 0051082=unfolded protein binding, 0030296=protein tyrosine kinase activator activity" "0022008=neurogenesis, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0035556=intracellular signal transduction, 0046579=positive regulation of Ras protein signal transduction" 0005737=cytoplasm "cdc37 protein, DROCPDR, CPDR-2, CPDR-1, CG12019, E(sev)3B, cdc37" "IPR004918=Cdc37, IPR013855=Cdc37, N-terminal domain, IPR013873=Cdc37, C-terminal, IPR013874=Cdc37, Hsp90 binding" CG12019 16-Dec-15 2015_12 ENSDARG00000040126(cdc37) YDR168W(CDC37) WBGene00021097(cdc-37) ENSXETG00000011625(cdc37) ENSMUSG00000019471(Cdc37) ENSG00000105401(CDC37) " embryonic stage | early , larval stage | third instar , embryonic stage | late " eye-antennal disc

"cell polarity defective,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,lethal,recessive,meiotic cell cycle defective,cytokinesis defective,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,increased cell size,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,somatic clone,eye photoreceptor cell,ommatidium,rhabdomere, with Df(3L)MY10,adult abdomen,spermatid,spindle,anaphase & condensed nuclear chromosome,actomyosin contractile ring,nucleus,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell" DRSC08648 K 1.321519302 -0.414487054 0.296851587 0.138160272 -0.27233522 2.459577781 FBgn0015984 l(2)PC4-M lethal (2) PC4-M http://flybase.net/reports/FBgn0015984.html gene l(2)PC4-E 16-Dec-15 2015_12 "lethal,recessive" FBgn0030260 CG1537 http://flybase.net/reports/FBgn0030260.html FBgn0063282 protein_coding_gene BcDNA:GH02938 CG1537 16-Dec-15 2015_12 viable FBgn0052702 Cubn Cubilin ortholog http://flybase.net/reports/FBgn0052702.html FBgn0030138 protein_coding_gene "0005509=calcium ion binding, 0004872=receptor activity" "0097017=renal protein absorption, 0097206=nephrocyte filtration, 0006898=receptor-mediated endocytosis" 0016020=membrane "TMPRSS6 iron sensing, dCubn, CG32702, tok-like, CT7882, CG2996, Cubilin, dCubilin" "IPR028876=Cubilin, IPR000859=CUB domain, IPR001881=EGF-like calcium-binding domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG32702 16-Dec-15 2015_12 ENSDARG00000071473 WBGene00013855(ZC116.3) ENSXETG00000007453(CUBN) ENSMUSG00000026726(Cubn) ENSG00000107611(CUBN) "viable,chemical sensitive" embryonic/larval pericardial cell FBgn0002238 l(3)68Be lethal (3) 68Be http://flybase.net/reports/FBgn0002238.html FBgn0002232 gene "C, l(3)C28, Complementation group C, l(3)C" 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0030587 CG9522 http://flybase.net/reports/FBgn0030587.html protein_coding_gene "0008812=choline dehydrogenase activity, 0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity" "0055114=oxidation-reduction process, 0045455=ecdysteroid metabolic process" Dm GMCiota1 "IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG9522 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) viable FBgn0034793 asrij asrij http://flybase.net/reports/FBgn0034793.html protein_coding_gene "0035167=larval lymph gland hemopoiesis, 0035162=embryonic hemopoiesis, 0046425=regulation of JAK-STAT cascade, 0048542=lymph gland development" "0016021=integral component of membrane, 0005769=early endosome, 0005794=Golgi apparatus, 0055037=recycling endosome, 0031410=cytoplasmic vesicle, 0005764=lysosome" "Dmasrij, FBgn 34793, Asrij, CG13533, arj" IPR009764=Ovarian carcinoma immunoreactive antigen CG13533 16-Dec-15 2015_12 "ENSDARG00000052334(ociad1),ENSDARG00000056677(LOC553528)" ENSXETG00000011673(TEgg067j10.1) ENSMUSG00000029152(Ociad1) ENSG00000109180(OCIAD1) "developmental rate defective,viable,fertile,mitotic cell cycle defective" "secondary lobe of embryonic/larval lymph gland,ectopic | third instar larval stage,plasmatocyte,ectopic,embryonic/larval hemocyte,medullary zone of lymph gland primary lobe" DRSC04175 E -0.547016561 -0.662511057 -1.547508917 0.615120558 -0.020152039 -0.898850601 FBgn0030975 SdhBL "Succinate dehydrogenase, subunit B (iron-sulfur)-like" http://flybase.net/reports/FBgn0030975.html protein_coding_gene "0000104=succinate dehydrogenase activity, 0051537=2 iron, 2 sulfur cluster binding, 0009055=electron carrier activity" 0006099=tricarboxylic acid cycle "0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)" "Ferredoxin, Succinate dehydrogenase Iron-sulfur protein, CG7349, DHSB, Succinate dehydrogenase [ubiquinone] iron-sulfur protein" "IPR012675=Beta-grasp domain, IPR009051=Alpha-helical ferredoxin, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR025192=Succinate dehydogenase/fumarate reductase N-terminal, IPR017900=4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR004489=Succinate dehydrogenase/fumarate reductase iron-sulphur protein, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain" CG7349 16-Dec-15 2015_12 YLL041C(SDH2) WBGene00006433(sdhb-1) FBgn0066355 l(3)51 lethal (3) 51 http://flybase.net/reports/FBgn0066355.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0267766 CR46097 http://flybase.net/reports/FBgn0267766.html non_protein_coding_gene CR46097 16-Dec-15 2015_12 FBgn0085452 CG34423 http://flybase.net/reports/FBgn0085452.html "FBan0011079, FBgn0034851, FBgn0062220" protein_coding_gene 0004857=enzyme inhibitor activity 0045980=negative regulation of nucleotide metabolic process 0005739=mitochondrion "CG11079, anon-WO0118547.139" "IPR007648=ATPase inhibitor, IATP, mitochondria" CG34423 16-Dec-15 2015_12 FBgn0036584 CG13054 http://flybase.net/reports/FBgn0036584.html protein_coding_gene CG13054 16-Dec-15 2015_12 DRSC29594 K -0.640629146 -0.691996366 0.287765517 -0.32164358 1.72270192 0.714228883 FBgn0030038 CG1440 http://flybase.net/reports/FBgn0030038.html protein_coding_gene 0004197=cysteine-type endopeptidase activity 0006508=proteolysis 0005829=cytosol "IPR000169=Cysteine peptidase, cysteine active site, IPR004134=Peptidase C1B, bleomycin hydrolase" CG1440 16-Dec-15 2015_12 ENSDARG00000025977(blmh) YNL239W(LAP3) ENSXETG00000021342(BLMH) ENSMUSG00000020840(Blmh) ENSG00000108578(BLMH) viable FBgn0051004 mesh mesh http://flybase.net/reports/FBgn0051004.html "FBgn0039825, FBgn0039826, FBgn0044637" protein_coding_gene "0090528=smooth septate junction assembly, 0007160=cell-matrix adhesion" 0005920=smooth septate junction "CG31004, CG15560, anon-WO0140519.233, CT5150, CG12074" "IPR000436=Sushi/SCR/CCP domain, IPR005533=AMOP domain, IPR002909=IPT domain, IPR003886=NIDO domain, IPR013783=Immunoglobulin-like fold, IPR001846=von Willebrand factor, type D domain, IPR014756=Immunoglobulin E-set" CG31004 16-Dec-15 2015_12 WBGene00010540(K03H1.5) ENSXETG00000019936(SUSD2) ENSMUSG00000006342(Susd2) ENSG00000099994(SUSD2) "lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,some die during pupal stage" "smooth septate junction | first instar larval stageExel6218),embryonic/larval midgut" FBgn0030390 CG15731 http://flybase.net/reports/FBgn0030390.html protein_coding_gene CG15731 16-Dec-15 2015_12 "viable,fertile" FBgn0027290 l(1)G0161 lethal (1) G0161 http://flybase.net/reports/FBgn0027290.html gene 16-Dec-15 2015_12 "lethal,female,recessive" FBgn0267065 CR45509 http://flybase.net/reports/FBgn0267065.html non_protein_coding_gene CR45509 16-Dec-15 2015_12 FBgn0043846 412\ORF4 ORF4 http://flybase.net/reports/FBgn0043846.html transposable_element_gene ORF4 16-Dec-15 2015_12 FBgn0085494 Mst77Y-16ë¬ Male-specific pseudogene 77Y 16 http://flybase.net/reports/FBgn0085494.html FBan0040530 pseudogene_attribute CG40530 CR40530 16-Dec-15 2015_12 FBgn0039630 CG11843 http://flybase.net/reports/FBgn0039630.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP43 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG11843 16-Dec-15 2015_12 "ENSXETG00000016792(plat),ENSXETG00000007245(F12),ENSXETG00000005495(HGFAC),ENSXETG00000018616(HABP2),ENSXETG00000010002(),ENSXETG00000004035(PRSS12)" "ENSMUSG00000025075(Habp2),ENSMUSG00000029102(Hgfac),ENSMUSG00000031538(Plat),ENSMUSG00000021822(Plau),ENSMUSG00000021492(F12),ENSMUSG00000027978(Prss12)" "viable,fertile" FBgn0027935 vu vesuvio http://flybase.net/reports/FBgn0027935.html gene 16-Dec-15 2015_12 FBgn0266309 CR44974 http://flybase.net/reports/FBgn0266309.html non_protein_coding_gene CR44974 16-Dec-15 2015_12 FBgn0005514 l(2)25Ea lethal (2) 25Ea http://flybase.net/reports/FBgn0005514.html gene "l(2)gdh11, l(2)jf25, jf25, l(2)gdh-11" 16-Dec-15 2015_12 "lethal,recessive" FBgn0033551 CG7222 http://flybase.net/reports/FBgn0033551.html protein_coding_gene IPR008580=PPPDE putative peptidase domain CG7222 16-Dec-15 2015_12 "ENSDARG00000004460(pppde1),ENSDARG00000053164" ENSXETG00000011391(PPPDE1) ENSMUSG00000026502(Pppde1) ENSG00000121644(PPPDE1) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0015975 l(2)PC4-A lethal (2) PC4-A http://flybase.net/reports/FBgn0015975.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039958 CG12567 http://flybase.net/reports/FBgn0039958.html FBan0012567 protein_coding_gene "0004788=thiamine diphosphokinase activity, 0016787=hydrolase activity" "IPR000086=NUDIX hydrolase domain, IPR015797=NUDIX hydrolase domain-like" CG12567 16-Dec-15 2015_12 ENSDARG00000058032(si:dkey-6n6.2) YJR142W() FBgn0028180 l(3)S024535b lethal (3) S024535b http://flybase.net/reports/FBgn0028180.html gene "88A, l(3)S024535, 0245/35" 16-Dec-15 2015_12 "lethal,recessive" FBgn0030041 CG12116 http://flybase.net/reports/FBgn0030041.html protein_coding_gene 0004757=sepiapterin reductase activity 0008152=metabolic process 144701_at "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG12116 16-Dec-15 2015_12 viable FBgn0051516 CG31516 http://flybase.net/reports/FBgn0051516.html "FBan0031516, FBgn0064861" protein_coding_gene BcDNA:RE68446 CG31516 16-Dec-15 2015_12 viable FBgn0046325 ms(2)38DEa ms(2)38DEa http://flybase.net/reports/FBgn0046325.html gene ms in 38D/E 16-Dec-15 2015_12 FBgn0060871 l(3)S047003 lethal (3) S047003 http://flybase.net/reports/FBgn0060871.html gene 0470/03 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027181 l(2)60A-M lethal (2) 60A-M http://flybase.net/reports/FBgn0027181.html gene 16-Dec-15 2015_12 "wild-type,lethal,recessive" FBgn0005006 dfi deformed eye http://flybase.net/reports/FBgn0005006.html gene rough-III 16-Dec-15 2015_12 "visible,viable,male,poor,female sterile,recessive" eye FBgn0034634 CG10494 http://flybase.net/reports/FBgn0034634.html protein_coding_gene IPR001005=SANT/Myb domain CG10494 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0069127 mei(3)M20 mei(3)M20 http://flybase.net/reports/FBgn0069127.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0265884 CR44673 http://flybase.net/reports/FBgn0265884.html non_protein_coding_gene CR44673 16-Dec-15 2015_12 FBgn0265868 CR44657 http://flybase.net/reports/FBgn0265868.html non_protein_coding_gene "lincRNA.993, l" CR44657 16-Dec-15 2015_12 FBgn0030278 CG15200 http://flybase.net/reports/FBgn0030278.html protein_coding_gene 0046692=sperm competition CG15200 16-Dec-15 2015_12 viable FBgn0039197 CG17780 http://flybase.net/reports/FBgn0039197.html FBgn0063676 protein_coding_gene BcDNA:RE41041 IPR006631=Protein of unknown function DM4/12 CG17780 16-Dec-15 2015_12 FBgn0025123 su(RpII140Z36)S5 su(RpII140Z36)S5 http://flybase.net/reports/FBgn0025123.html gene Z36[S5] 16-Dec-15 2015_12 FBgn0004811 fs(2)ltoPP43 female sterile (2) ltoPP43 http://flybase.net/reports/FBgn0004811.html "FBgn0026579, FBgn0032823" protein_coding_gene 0007304=chorion-containing eggshell formation "BEST:LD12957, CG10528, l(2)38Ac, LD12957" IPR013883=Transcription factor Iwr1 CG10528 16-Dec-15 2015_12 ENSMUSG00000033106(Slc7a6os) "viable,fertile,lethal,recessive,visible,wild-type,long lived,female sterile" "eye,trichogen cell,mesothoracic tergum" FBgn0267469 CR45819 http://flybase.net/reports/FBgn0267469.html non_protein_coding_gene CR45819 16-Dec-15 2015_12 FBgn0259925 p150 http://flybase.net/reports/FBgn0259925.html protein_coding_gene 16-Dec-15 2015_12 FBgn0067659 sbg strindberg http://flybase.net/reports/FBgn0067659.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 female sterile FBgn0267425 CR45778 http://flybase.net/reports/FBgn0267425.html non_protein_coding_gene Mgn99994 CR45778 16-Dec-15 2015_12 FBgn0026384 Or59a Odorant receptor 59a http://flybase.net/reports/FBgn0026384.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "DOR59D.1, Or46, 59D.1, DOR46, CG9820, AN6, Olfactory receptor 59D.1, dor46, 59a, Or59D.1" "IPR004117=Olfactory receptor, Drosophila" CG9820 16-Dec-15 2015_12 adult stage sensory neuron &&of antennal segment 3

smell perception defective FBgn0033942 Cpr51A Cuticular protein 51A http://flybase.net/reports/FBgn0033942.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0040003=chitin-based cuticle development, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0031012=extracellular matrix" CG10112 IPR000618=Insect cuticle protein CG10112 16-Dec-15 2015_12 viable FBgn0003511 Sry-ë_ Serendipity ë_ http://flybase.net/reports/FBgn0003511.html protein_coding_gene "0046872=metal ion binding, 0003677=DNA binding" "0005634=nucleus, 0005705=polytene chromosome interband" "sry-b, serendipity beta, sry, sryb, ser, serendipity, sry beta, CG7938, sry-beta, Sry-beta, srybeta, Srybeta" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG7938 16-Dec-15 2015_12 embryonic stage -- adult stage "partially lethal - majority die,some die during pupal stage" FBgn0264419 FCO-D http://flybase.net/reports/FBgn0264419.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0060347 l(3)S143206 lethal (3) S143206 http://flybase.net/reports/FBgn0060347.html gene 1432/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065635 l(2)SH0770 lethal (2) SH0770 http://flybase.net/reports/FBgn0065635.html gene l(2)SH2 0770 16-Dec-15 2015_12 "lethal,recessive" FBgn0267479 CR45829 http://flybase.net/reports/FBgn0267479.html non_protein_coding_gene CR45829 16-Dec-15 2015_12 FBgn0030801 Rcp Receptor component protein http://flybase.net/reports/FBgn0030801.html protein_coding_gene "0000166=nucleotide binding, 0003899=DNA-directed RNA polymerase activity, 0004930=G-protein coupled receptor activity" "0045745=positive regulation of G-protein coupled receptor protein signaling pathway, 0048812=neuron projection morphogenesis, 0006351=transcription, DNA-templated" "receptor component protein, dRCP, CG4875" "IPR005574=RNA polymerase II, Rpb4, IPR010997=HRDC-like, IPR006590=RNA polymerase II, Rpb4, core" CG4875 16-Dec-15 2015_12 ENSMUSG00000025532(Crcp) "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" mesothoracic tergum FBgn0037842 CG6567 http://flybase.net/reports/FBgn0037842.html protein_coding_gene 0004622=lysophospholipase activity "IPR003140=Phospholipase/carboxylesterase/thioesterase, IPR029058=Alpha/Beta hydrolase fold" CG6567 16-Dec-15 2015_12 ENSDARG00000039076 ENSXETG00000015359(BC086497.1) ENSMUSG00000039246(Lyplal1) ENSG00000143353(LYPLAL1) "viable,fertile" FBgn0060631 l(3)S085505 lethal (3) S085505 http://flybase.net/reports/FBgn0060631.html gene 0855/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0001658 l(1)ds12 lethal (1) discs small 12 http://flybase.net/reports/FBgn0001658.html gene l(1)1-45 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0065707 l(2)SH0610 lethal (2) SH0610 http://flybase.net/reports/FBgn0065707.html gene l(2)SH2 0610 16-Dec-15 2015_12 "lethal,recessive" FBgn0039667 CG2010 http://flybase.net/reports/FBgn0039667.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXL3 IPR001810=F-box domain CG2010 16-Dec-15 2015_12 WBGene00020884(T28B4.1) FBgn0031635 tank tank http://flybase.net/reports/FBgn0031635.html protein_coding_gene 1901418=positive regulation of response to ethanol "CG15626, tank" IPR009890=Etoposide-induced 2.4 CG15626 16-Dec-15 2015_12 WBGene00018150(eip-24) ENSXETG00000017779(EI24) ENSMUSG00000062762(Ei24) ENSG00000149547(EI24) "chemical resistant,partially lethal - majority die,some die during pupal stage,lethal" FBgn0013257 E(var)3118 E(var)3118 http://flybase.net/reports/FBgn0013257.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0024866 l(3)04679 lethal (3) 04679 http://flybase.net/reports/FBgn0024866.html gene 4679 16-Dec-15 2015_12 "lethal,recessive" FBgn0011229 pto pistachio http://flybase.net/reports/FBgn0011229.html gene 0007286=spermatid development 16-Dec-15 2015_12 male semi-sterile FBgn0060336 l(3)S144607a lethal (3) S144607a http://flybase.net/reports/FBgn0060336.html gene 1446/07 16-Dec-15 2015_12 lethal FBgn0040950 Muc26B Mucin 26B http://flybase.net/reports/FBgn0040950.html FBgn0047122 protein_coding_gene "0008061=chitin binding, 0005201=extracellular matrix structural constituent" "0006030=chitin metabolic process, 0048812=neuron projection morphogenesis" "0031012=extracellular matrix, 0005576=extracellular region" "BcDNA:RE30702, Muc26B, CG13990" IPR002557=Chitin binding domain CG13990 16-Dec-15 2015_12 viable DRSC02322 E -0.818958477 0.202858201 1.850548973 0.333261046 0.470494197 -0.84474961 FBgn0005353 su(B)2 suppressor of Bar on 2 http://flybase.net/reports/FBgn0005353.html gene 16-Dec-15 2015_12 FBgn0028358 l(1)G0151 lethal (1) G0151 http://flybase.net/reports/FBgn0028358.html gene 16-Dec-15 2015_12 "lethal,recessive" chaeta FBgn0002889 mus203 mutagen-sensitive 203 http://flybase.net/reports/FBgn0002889.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive,radiation sensitive" FBgn0011160 l(1)Q238 lethal (1) Q238 http://flybase.net/reports/FBgn0011160.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0265659 CR44466 http://flybase.net/reports/FBgn0265659.html non_protein_coding_gene lincRNA.328 CR44466 16-Dec-15 2015_12 FBgn0052785 tRNA:CR32785 transfer RNA:CR32785 http://flybase.net/reports/FBgn0052785.html FBgn0060109 tRNA_gene 0033428=CAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002566.trna1-GlnCTG, CR32785, tRNA:Q:CTG:AE002566, chrX.trna1-GlnCTG" CR32785 16-Dec-15 2015_12 FBgn0039857 RpL6 Ribosomal protein L6 http://flybase.net/reports/FBgn0039857.html protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0051297=centrosome organization, 0051298=centrosome duplication, 0000022=mitotic spindle elongation" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "CG11522, rpl6, Rp L6, RPL6" "IPR008991=Translation protein SH3-like domain, IPR005568=Ribosomal protein L6, N-terminal, IPR014722=Ribosomal protein L2 domain 2, IPR000915=60S ribosomal protein L6E" CG11522 16-Dec-15 2015_12 ENSDARG00000058451(rpl6) "YLR448W(RPL6B),YML073C(RPL6A)" WBGene00004417(rpl-6) ENSXETG00000004304() "ENSMUSG00000029614(Rpl6),ENSMUSG00000057605(Gm6807)" ENSG00000089009(RPL6) DRSC14323 IEK 4.084981903 -1.009584704 2.967252844 -3.457939169 0.733726893 4.0728822 FBgn0005189 l(2)S45 lethal of Seto 45 http://flybase.net/reports/FBgn0005189.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" leg FBgn0062684 EP1555 EP1555 http://flybase.net/reports/FBgn0062684.html gene EP(X)1555 16-Dec-15 2015_12 FBgn0262279 mir-983-2 mir-983-2 stem loop http://flybase.net/reports/FBgn0262279.html miRNA_gene "miR-983, CR42986, 983-2, miR-983-2" CR42986 16-Dec-15 2015_12 "visible,lethal" wing FBgn0032096 Or30a Odorant receptor 30a http://flybase.net/reports/FBgn0032096.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "CG13106, 30a, 30A.1, DOR56" "IPR004117=Olfactory receptor, Drosophila" CG13106 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0033400 CG2063 http://flybase.net/reports/FBgn0033400.html protein_coding_gene "0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" IPR012479=SAP30-binding protein CG2063 16-Dec-15 2015_12 ENSDARG00000031261(sap30bp) WBGene00022057(Y67D2.7) ENSXETG00000012553(SAP30BP) ENSMUSG00000020755(Sap30bp) ENSG00000161526(SAP30BP) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC06811 K 0.074324906 1.070768493 -0.041174307 0.753273232 -1.502907091 -1.19622964 FBgn0263998 Ack-like Activated Cdc42 kinase-like http://flybase.net/reports/FBgn0263998.html "FBgn0013955, FBgn0019939, FBgn0022801, FBgn0053007" protein_coding_gene "0004715=non-membrane spanning protein tyrosine kinase activity, 0005524=ATP binding, 0004713=protein tyrosine kinase activity" "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0006468=protein phosphorylation" "DRODPR2, CG43741, dACK, HD-11, CG33007, tyrosine kinase, Fak-like tyrosine kinase, PR2, DPR2, DmHD-11, CG3969, Rp2, PR2/ACK" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR001452=SH3 domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR000095=CRIB domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR011511=Variant SH3 domain" CG43741 16-Dec-15 2015_12 FBgn0034509 Obp57c Odorant-binding protein 57c http://flybase.net/reports/FBgn0034509.html FBgn0061367 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG13421, BcDNA:RH68952, 57c, obp57c, Obp57a, DmelObp57c" IPR006170=Pheromone/general odorant binding protein CG13421 16-Dec-15 2015_12 viable FBgn0040647 CG10987 http://flybase.net/reports/FBgn0040647.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0262272 mir-1002 mir-1002 stem loop http://flybase.net/reports/FBgn0262272.html miRNA_gene "miR-1002, CR42979, 1002, dme-miR-1002-5p" CR42979 16-Dec-15 2015_12 viable FBgn0263468 snoRNA:SC35-a http://flybase.net/reports/FBgn0263468.html snoRNA_gene snoHACA_01 CR43583 16-Dec-15 2015_12 FBgn0010334 X81 X81 http://flybase.net/reports/FBgn0010334.html gene 16-Dec-15 2015_12 FBgn0264348 CR43804 http://flybase.net/reports/FBgn0264348.html non_protein_coding_gene CR43804 16-Dec-15 2015_12 FBgn0265633 CR44440 http://flybase.net/reports/FBgn0265633.html non_protein_coding_gene lincRNA.918 CR44440 16-Dec-15 2015_12 FBgn0266046 CR44811 http://flybase.net/reports/FBgn0266046.html non_protein_coding_gene CR44811 16-Dec-15 2015_12 FBgn0065746 l(2)SH0516 lethal (2) SH0516 http://flybase.net/reports/FBgn0065746.html gene l(2)SH2 0516 16-Dec-15 2015_12 "lethal,recessive" FBgn0028427 Ilk Integrin linked kinase http://flybase.net/reports/FBgn0028427.html "FBgn0013568, FBgn0037062" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0016203=muscle attachment, 0007155=cell adhesion, 0007229=integrin-mediated signaling pathway, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0007016=cytoskeletal anchoring at plasma membrane, 0007160=cell-matrix adhesion, 0006468=protein phosphorylation" 0005925=focal adhesion "integrin-linked kinase, CT29478, l(3)78Ca, Integrin Linked Kinase, CG10504, Integrin-linked kinase, integrin linked kinase, ILK, DmILK, ilk" "IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR011009=Protein kinase-like domain" CG10504 16-Dec-15 2015_12 ENSDARG00000056964(ilk) WBGene00003931(pat-4) ENSXETG00000021402(ILK) ENSMUSG00000030890(Ilk) ENSG00000166333(ILK) "wild-type,lethal,visible,recessive,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of first instar larval stage,viable" "embryonic/larval somatic muscle,wing,somatic clone,muscle fiber,heat sensitive" FBgn0085732 CR40190 http://flybase.net/reports/FBgn0085732.html FBan0040190 pseudogene_attribute CR40190 16-Dec-15 2015_12 FBgn0026637 l(2)k13910 lethal (2) k13910 http://flybase.net/reports/FBgn0026637.html gene 16-Dec-15 2015_12 FBgn0038678 mRpL55 mitochondrial ribosomal protein L55 http://flybase.net/reports/FBgn0038678.html FBgn0047041 protein_coding_gene "0003735=structural constituent of ribosome, 0003700=sequence-specific DNA binding transcription factor activity, 0003729=mRNA binding" 0006412=translation "0005730=nucleolus, 0005762=mitochondrial large ribosomal subunit, 0005739=mitochondrion, 0005634=nucleus" "CG14283, tmb, BcDNA:RH10246, tom thumb, MRP-L55" "IPR018615=Ribosomal protein L55, mitochondrial" CG14283 16-Dec-15 2015_12 ENSDARG00000043402(zgc:171480) WBGene00022045(tag-313) ENSMUSG00000036860(Mrpl55) ENSG00000162910(MRPL55) "developmental rate defective,female sterile,germline clone,cell lethal,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,viable,fertile,visible" "actin filament | somatic cloneGMR.PU, cdiR47,trichogen cell" FBgn0264434 CR43852 http://flybase.net/reports/FBgn0264434.html non_protein_coding_gene CR43852 16-Dec-15 2015_12 FBgn0036028 CG16717 http://flybase.net/reports/FBgn0036028.html protein_coding_gene 0016787=hydrolase activity "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like, IPR024201=Calcineurin-like phosphoesterase" CG16717 16-Dec-15 2015_12 "ENSDARG00000006889(zgc:112142),ENSDARG00000034443(mpped2),ENSDARG00000069642" WBGene00011579(T07D4.2) "ENSXETG00000021376(TEgg042m08.),ENSXETG00000004861(MPPED1)" "ENSMUSG00000041708(Mpped1),ENSMUSG00000016386" "ENSG00000066382(MPPED2),ENSG00000186732(MPPED1)" viable FBgn0262947 CG43266 http://flybase.net/reports/FBgn0262947.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004641 E(sev)3D Enhancer of sevenless 3D http://flybase.net/reports/FBgn0004641.html gene H214 16-Dec-15 2015_12 "lethal,recessive" FBgn0001359 l(1)1EFh lethal (1) 1EFh http://flybase.net/reports/FBgn0001359.html gene l(1)BA8 16-Dec-15 2015_12 lethal FBgn0266753 CR45226 http://flybase.net/reports/FBgn0266753.html non_protein_coding_gene CR45226 16-Dec-15 2015_12 FBgn0065941 l(2)SH0115 lethal (2) SH0115 http://flybase.net/reports/FBgn0065941.html gene l(2)SH2 0115 16-Dec-15 2015_12 "lethal,recessive" FBgn0019663 ply paisley http://flybase.net/reports/FBgn0019663.html gene 16-Dec-15 2015_12 "visible,recessive,cold sensitive" wing hair FBgn0028623 l(2)05095a lethal (2) 05095a http://flybase.net/reports/FBgn0028623.html gene l(2)05095 16-Dec-15 2015_12 "lethal,recessive" FBgn0014860 Lcch2 Ligand-gated chloride channel homolog 2 http://flybase.net/reports/FBgn0014860.html gene LCCH2 16-Dec-15 2015_12 FBgn0267638 CR45976 http://flybase.net/reports/FBgn0267638.html non_protein_coding_gene CR45976 16-Dec-15 2015_12 FBgn0017429 CG5989 http://flybase.net/reports/FBgn0017429.html protein_coding_gene "anon-66Db, anonymous-66Db, SAM methionine methyltransferase, unnamed" "IPR003100=PAZ domain, IPR011685=LETM1-like" CG5989 16-Dec-15 2015_12 ENSDARG00000030641(zgc:194455) WBGene00009276(F30F8.9) ENSXETG00000009635(letmd1) ENSMUSG00000037353(Letmd1) ENSG00000050426(LETMD1) viable FBgn0065423 l(2)SH1519 lethal (2) SH1519 http://flybase.net/reports/FBgn0065423.html gene l(2)SH2 1519 16-Dec-15 2015_12 "lethal,recessive" FBgn0051665 wry weary http://flybase.net/reports/FBgn0051665.html "FBgn0031368, FBgn0031369" protein_coding_gene "0005112=Notch binding, 0005509=calcium ion binding" "0007219=Notch signaling pathway, 0003015=heart process" 0009986=cell surface "fibropellin, CG12704, CT35769, CG31665, CG15621" "IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR001881=EGF-like calcium-binding domain, IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR009030=Insulin-like growth factor binding protein, N-terminal" CG31665 16-Dec-15 2015_12 ENSG00000169894(MUC3A) viable "adult heart,heat sensitive" DRSC00456 K 0.223670984 0.796397097 0.082206128 0.636242073 -0.640880008 -1.553549396 FBgn0000510 Dt Detached http://flybase.net/reports/FBgn0000510.html gene 16-Dec-15 2015_12 FBgn0036484 Pex3 Peroxin 3 http://flybase.net/reports/FBgn0036484.html protein_coding_gene "0030497=fatty acid elongation, 0007031=peroxisome organization, 2000304=positive regulation of ceramide biosynthetic process" "0005777=peroxisome, 0005779=integral component of peroxisomal membrane" "peroxin 3, pex3, CG6859, PEX3, DmelPex3, peroxisomal multifunctional enzyme type 2" IPR006966=Peroxin-3 CG6859 16-Dec-15 2015_12 ENSDARG00000013973(pex3) ENSXETG00000009788(pex3) ENSMUSG00000019809(Pex3) ENSG00000034693(PEX3) "viable,lethal - all die before end of larval stage,recessive,some die during larval stage" peroxisome DRSC10731 K -0.061623959 -0.277858694 0.260979855 1.005999907 2.022460592 0.286486407 FBgn0084764 EP3123 EP3123 http://flybase.net/reports/FBgn0084764.html gene 16-Dec-15 2015_12 FBgn0036177 CG33268 http://flybase.net/reports/FBgn0036177.html FBgn0053268 protein_coding_gene CG14138 CG33268 16-Dec-15 2015_12 FBgn0265536 CR44386 http://flybase.net/reports/FBgn0265536.html non_protein_coding_gene lincRNA.331 CR44386 16-Dec-15 2015_12 FBgn0036348 CG17687 http://flybase.net/reports/FBgn0036348.html protein_coding_gene "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG17687 16-Dec-15 2015_12 ENSG00000197748(WDR96) FBgn0036872 CG12519 http://flybase.net/reports/FBgn0036872.html FBgn0047100 protein_coding_gene CG12519 16-Dec-15 2015_12 FBgn0029874 CG3342 http://flybase.net/reports/FBgn0029874.html protein_coding_gene CG3342 16-Dec-15 2015_12 "ENSDARG00000059778(si:dkey-90l8.4),ENSDARG00000054947(LOC799923)" ENSXETG00000003941(FKBP15) ENSG00000119321(FKBP15) "viable,fertile" FBgn0005241 l(3)R88 lethal of Roberts 88 http://flybase.net/reports/FBgn0005241.html gene l(3)B88 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0003221 rdp reduplicated http://flybase.net/reports/FBgn0003221.html gene 16-Dec-15 2015_12 "leg,cold sensitive" FBgn0039765 mRpS18C mitochondrial ribosomal protein S18C http://flybase.net/reports/FBgn0039765.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "mRpS18a, MRP-S18-(1), mitochondrial ribosomal protein S18a, CG9688" IPR001648=Ribosomal protein S18 CG9688 16-Dec-15 2015_12 ENSDARG00000069624(LOC100333338) WBGene00020499(T14B4.2) ENSXETG00000027597(TEgg001i12.1) ENSMUSG00000016833(Mrps18c) ENSG00000163319(MRPS18C) "viable,visible" trichogen cell FBgn0264725 CG43993 http://flybase.net/reports/FBgn0264725.html protein_coding_gene CG43993 16-Dec-15 2015_12 FBgn0265424 CR44336 http://flybase.net/reports/FBgn0265424.html non_protein_coding_gene CR44336 16-Dec-15 2015_12 FBgn0001761 l(1)M16 lethal (1) M16 http://flybase.net/reports/FBgn0001761.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259525 GG01477 http://flybase.net/reports/FBgn0259525.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing vein L3,tarsal segment" FBgn0028186 l(3)S023941c lethal (3) S023941c http://flybase.net/reports/FBgn0028186.html gene "l(3)S023941, 0239/41" 16-Dec-15 2015_12 "lethal,recessive" FBgn0011919 tRNA:M2:83F transfer RNA:met2:83F http://flybase.net/reports/FBgn0011919.html "FBgn0051310, FBgn0060141" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033436=AUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002699.trna7-MetCAT, tRNA:M:CAT:AE002699, tRNA:met2:83F, Met-2, CR31310, chr3R.trna80-MetCAT, tRNA[[e]][Met]" CR31310 16-Dec-15 2015_12 FBgn0065261 l(2)SH2086 lethal (2) SH2086 http://flybase.net/reports/FBgn0065261.html gene l(2)SH2 2086 16-Dec-15 2015_12 "lethal,recessive" FBgn0265915 CR44704 http://flybase.net/reports/FBgn0265915.html non_protein_coding_gene CR44704 16-Dec-15 2015_12 FBgn0035611 CG13285 http://flybase.net/reports/FBgn0035611.html protein_coding_gene FBgn0035611 CG13285 16-Dec-15 2015_12 viable FBgn0259417 C926 http://flybase.net/reports/FBgn0259417.html gene 16-Dec-15 2015_12 visible wing vein FBgn0065286 l(2)SH2021 lethal (2) SH2021 http://flybase.net/reports/FBgn0065286.html gene l(2)SH2 2021 16-Dec-15 2015_12 "lethal,recessive" FBgn0045050 fs(1)250 female sterile (1) 250 http://flybase.net/reports/FBgn0045050.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "ovary,egg" FBgn0267676 CR46012 http://flybase.net/reports/FBgn0267676.html non_protein_coding_gene CR46012 16-Dec-15 2015_12 FBgn0260766 CG42564 http://flybase.net/reports/FBgn0260766.html FBgn0037441 protein_coding_gene "0032504=multicellular organism reproduction, 0050829=defense response to Gram-negative bacterium" "0005576=extracellular region, 0005615=extracellular space" CG10284 "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG42564 16-Dec-15 2015_12 viable FBgn0262904 CR43259 http://flybase.net/reports/FBgn0262904.html non_protein_coding_gene CR43259 16-Dec-15 2015_12 FBgn0040679 CG11373 http://flybase.net/reports/FBgn0040679.html protein_coding_gene CG11373 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0020235 ATPsynë_ "ATP synthase, ë_ subunit" http://flybase.net/reports/FBgn0020235.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0006909=phagocytosis, 0015986=ATP synthesis coupled proton transport, 0015992=proton transport" "0005739=mitochondrion, 0005811=lipid particle, 0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)" "CG7610, F0/F1 ATP synthase Gamma, ATPsyn-gamma, ATP synthase subunit gamma, ATPsyn-gam, ATPG_DROME, ATPsyn-gamma chain, ATP synthase-gamma chain, ATP synthase Gamma chain, ATP synthase gamma chain, ATPG, catalytic core of F1 ATP synthase of complex V, F1ATP synthase" "IPR023632=ATPase, F1 complex, gamma subunit conserved site, IPR023633=ATPase, F1 complex, gamma subunit domain, IPR000131=ATPase, F1 complex, gamma subunit" CG7610 16-Dec-15 2015_12 ENSDARG00000045514(atp5c1) YBR039W(ATP3) WBGene00022089(Y69A2AR.18) ENSXETG00000001868(ATP5C1) ENSMUSG00000025781(Atp5c1) ENSG00000165629(ATP5C1) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC14094 K -0.302446263 -0.192940616 -0.880534713 -1.005323255 1.829306441 1.573020866 FBgn0065703 l(2)SH0619 lethal (2) SH0619 http://flybase.net/reports/FBgn0065703.html gene l(2)SH2 0619 16-Dec-15 2015_12 "lethal,recessive" FBgn0029606 CG14052 http://flybase.net/reports/FBgn0029606.html protein_coding_gene CG14052 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC17907 I 2.181155943 -0.960851091 1.260429562 0.326207364 -0.084858147 0.354267025 FBgn0265756 CR44563 http://flybase.net/reports/FBgn0265756.html non_protein_coding_gene lincRNA.588 CR44563 16-Dec-15 2015_12 FBgn0023198 JmY Ju-myoY http://flybase.net/reports/FBgn0023198.html gene "Jm Y, Y" 16-Dec-15 2015_12 aging defective FBgn0085466 CG34437 http://flybase.net/reports/FBgn0085466.html "FBan0016918, FBgn0039574" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG16918, SPH201" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG34437 16-Dec-15 2015_12 FBgn0060455 l(3)S118608 lethal (3) S118608 http://flybase.net/reports/FBgn0060455.html gene 1186/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0040337 CG3021 http://flybase.net/reports/FBgn0040337.html "FBgn0014905, FBgn0029554" protein_coding_gene "0004808=tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity, 0016783=sulfurtransferase activity" 0008033=tRNA processing "E, EG:BACR7A4.8, anon-1Ed, Transcription unit E" "IPR023382=Adenine nucleotide alpha hydrolase-like domains, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR004506=tRNA-specific 2-thiouridylase" CG3021 16-Dec-15 2015_12 ENSDARG00000043734(trmu) YDL033C(SLM3) WBGene00007114(B0035.16) ENSXETG00000023304(TRMU) ENSMUSG00000022386(Trmu) ENSG00000100416(TRMU) viable FBgn0003580 Su(sph) Suppressor of sparse hairs http://flybase.net/reports/FBgn0003580.html gene Su-x4 16-Dec-15 2015_12 FBgn0015978 l(2)PC4-D lethal (2) PC4-D http://flybase.net/reports/FBgn0015978.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026639 l(2)k10613 lethal (2) k10613 http://flybase.net/reports/FBgn0026639.html gene 16-Dec-15 2015_12 FBgn0036652 CG13032 http://flybase.net/reports/FBgn0036652.html protein_coding_gene CG13032 16-Dec-15 2015_12 ENSDARG00000063451(LOC555345) ENSG00000173811 viable FBgn0040648 CG11666 http://flybase.net/reports/FBgn0040648.html protein_coding_gene CG11666 16-Dec-15 2015_12 viable FBgn0067348 l(3)95Ed lethal (3) 95Ed http://flybase.net/reports/FBgn0067348.html gene 16-Dec-15 2015_12 "lethal,recessive" "eye,somatic clone,wing margin,macrochaeta" FBgn0020369 Rpt6 Regulatory particle triple-A ATPase 6 http://flybase.net/reports/FBgn0020369.html FBgn0023422 protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity, 0016787=hydrolase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005838=proteasome regulatory particle, 0005737=cytoplasm, 0005634=nucleus, 0008540=proteasome regulatory particle, base subcomplex, 0005875=microtubule associated complex" "Dm_Rpt6a, sug1, p42C, S8, pros45, sug-1, DUG, 26S proteasome regulatory subunit 8, Dug, CG1489, Ug, 1489, proteasomal subunit 8, Rpt6, PRS8_DROME, Pros45, dRpt6" "IPR005937=26S proteasome subunit P45, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain" CG1489 16-Dec-15 2015_12 ENSDARG00000015315(psmc5) YGL048C(RPT6) "WBGene00004506(rpt-6),WBGene00018991(F56F11.4)" ENSXETG00000014234(psmc5) ENSMUSG00000020708(Psmc5) ENSG00000087191(PSMC5) " embryonic stage | stage 13 , embryonic stage | stage 16 , adult stage | male , embryonic stage--pupal stage , larval stage | first instar , embryonic stage | early , adult stage | female , embryonic stage " " posterior midgut proper primordium

, embryonic central nervous system

, anterior midgut proper primordium

, larval nervous system

,

ubiquitous , pole cell | stage 5-8

" embryonic stage -- adult stage "viable,fertile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069419 JJF106 JJF106 http://flybase.net/reports/FBgn0069419.html gene 16-Dec-15 2015_12 stress response defective FBgn0031333 CG5561 http://flybase.net/reports/FBgn0031333.html protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process "IPR006439=HAD hydrolase, subfamily IA, IPR023214=HAD-like domain" CG5561 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0004528 l(4)102ABe lethal (4) 102ABe http://flybase.net/reports/FBgn0004528.html gene "l(4)35, l(4)18" 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" FBgn0267569 CR45909 http://flybase.net/reports/FBgn0267569.html non_protein_coding_gene CR45909 16-Dec-15 2015_12 FBgn0000519 dwf dwarfoid http://flybase.net/reports/FBgn0000519.html gene 16-Dec-15 2015_12 "visible,viable,reduced,male fertile,female fertile,female sterile,recessive,poor" "adult abdomen,adult thorax" FBgn0029513 Abd-B-PTS Abdominal B promoter targeting sequence http://flybase.net/reports/FBgn0029513.html regulatory_region "PTS, PTS-7" 16-Dec-15 2015_12 FBgn0003259 Rm2 Ring magnifier on 2 http://flybase.net/reports/FBgn0003259.html gene Ring magnifier on chromosome 2 16-Dec-15 2015_12 FBgn0032372 CG4988 http://flybase.net/reports/FBgn0032372.html protein_coding_gene "0030246=carbohydrate binding, 0003978=UDP-glucose 4-epimerase activity" 0019318=hexose metabolic process "IPR015443=Aldose 1-epimerase, IPR011013=Galactose mutarotase-like domain, IPR014718=Glycoside hydrolase-type carbohydrate-binding, subgroup, IPR008183=Aldose 1-/Glucose-6-phosphate 1-epimerase" CG4988 16-Dec-15 2015_12 ENSDARG00000057630(galm) "YHR210C(),YNR071C()" WBGene00015270(C01B4.6) ENSXETG00000009022(GALM) ENSMUSG00000035473(Galm) ENSG00000143891(GALM) FBgn0033880 CG6553 http://flybase.net/reports/FBgn0033880.html protein_coding_gene "IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000436=Sushi/SCR/CCP domain" CG6553 16-Dec-15 2015_12 WBGene00008609(F09B12.5) viable FBgn0028263 l(2)56Da lethal (2) 56Da http://flybase.net/reports/FBgn0028263.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0011445 l(3)neo1 lethal (3) neo1 http://flybase.net/reports/FBgn0011445.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036372 Abp1 Actin binding protein 1 http://flybase.net/reports/FBgn0036372.html protein_coding_gene "0005547=phosphatidylinositol-3,4,5-trisphosphate binding, 0003779=actin binding, 0001786=phosphatidylserine binding, 0051015=actin filament binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding" "0022416=chaeta development, 0016477=cell migration, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0072553=terminal button organization" "0031594=neuromuscular junction, 0030424=axon, 0005884=actin filament, 0005938=cell cortex, 0061177=type Is terminal bouton, 0005856=cytoskeleton, 0061176=type Ib terminal bouton, 0030864=cortical actin cytoskeleton, 0030426=growth cone" "abp1, CG10083, Drebrin-like" "IPR029006=ADF-H/Gelsolin-like domain, IPR002108=Actin-depolymerising factor homology domain, IPR001452=SH3 domain" CG10083 16-Dec-15 2015_12 ENSDARG00000008170(zgc:91835) YCR088W(ABP1) WBGene00010664(K08E3.4) ENSXETG00000019013(DBNL) ENSMUSG00000020476(Dbnl) ENSG00000136279(DBNL) "viable,fertile" "microchaeta,dorsocentral bristle" FBgn0028376 gut-X gut-X http://flybase.net/reports/FBgn0028376.html gene 16-Dec-15 2015_12 FBgn0083918 CTTbp CTT DNA binding protein http://flybase.net/reports/FBgn0083918.html gene 16-Dec-15 2015_12 FBgn0260754 CG42552 http://flybase.net/reports/FBgn0260754.html protein_coding_gene mdcds_30721 16-Dec-15 2015_12 FBgn0085755 CR40611 http://flybase.net/reports/FBgn0085755.html FBan0040611 rRNA_gene CR40611 16-Dec-15 2015_12 FBgn0261532 cdm cadmus http://flybase.net/reports/FBgn0261532.html "FBgn0038574, FBgn0067650" protein_coding_gene 0008536=Ran GTPase binding "0007270=neuron-neuron synaptic transmission, 0050804=regulation of synaptic transmission, 0042331=phototaxis, 0006886=intracellular protein transport" "importin 13, Cadmus, complementation group 5, CG 7212, Importin 13, 3R23, CG7212, Imp13, sd-5, imp13" "IPR013598=Exportin-1/Importin-beta-like, IPR011989=Armadillo-like helical, IPR001494=Importin-beta, N-terminal domain, IPR016024=Armadillo-type fold" CG7212 16-Dec-15 2015_12 WBGene00011807(T16G12.6) ENSXETG00000003491(IPO13) ENSMUSG00000033365(Ipo13) ENSG00000117408(IPO13) FBgn0022809 E(faf)bE184 Enhancer of faf bE184 http://flybase.net/reports/FBgn0022809.html gene 16-Dec-15 2015_12 visible "eye,wing" FBgn0035949 CG13314 http://flybase.net/reports/FBgn0035949.html protein_coding_gene CG13314 16-Dec-15 2015_12 FBgn0041739 l(2)EL3 lethal (2) EL3 http://flybase.net/reports/FBgn0041739.html gene 16-Dec-15 2015_12 lethal FBgn0000496 drw droopy wings http://flybase.net/reports/FBgn0000496.html gene "droopy wing, dr" 16-Dec-15 2015_12 "visible,recessive,viable,male,reduced,male sterile,body color defective" "wing,adult cuticle & abdomen,microchaeta,trichome" FBgn0003930 snRNA:U4:39B small nuclear RNA U4 at 39B http://flybase.net/reports/FBgn0003930.html "FBgn0003929, FBgn0021997, FBgn0051625" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005687=U4 snRNP "small nuclear RNA U4, K3, U4:39B, U4, U4 small nuclear RNA, chr2L:21202607..21202764, snRNA:U4, U4 snRNA gene at 39B, U4:39B snRNA, l(2)k09410, CR31625, U4 snRNA, U4-39B, U4snRNA, U4-2, dU4, U4snRNA39B" CR31625 16-Dec-15 2015_12 "lethal,recessive" FBgn0065844 l(2)SH0320 lethal (2) SH0320 http://flybase.net/reports/FBgn0065844.html gene l(2)SH2 0320 16-Dec-15 2015_12 "lethal,recessive" FBgn0060705 l(3)S070806c lethal (3) S070806c http://flybase.net/reports/FBgn0060705.html gene 0708/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0039474 CG6283 http://flybase.net/reports/FBgn0039474.html protein_coding_gene "0016298=lipase activity, 0008970=phosphatidylcholine 1-acylhydrolase activity" 0016042=lipid catabolic process "Triglyceride lipase, DmelL3" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR002334=Vespid venom allergen phospholipase A1, IPR000734=Triacylglycerol lipase family" CG6283 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0264672 Eogt EGF-domain O-GlcNAc transferase http://flybase.net/reports/FBgn0264672.html "FBgn0031421, FBgn0264615" protein_coding_gene 0097363=protein O-GlcNAc transferase activity "0097370=protein O-GlcNAcylation via threonine, 0006493=protein O-linked glycosylation, 0008363=larval chitin-based cuticle development" 0005788=endoplasmic reticulum lumen "eogt, CG9867" "IPR007657=Glycosyltransferase AER61, uncharacterised" CG9867 16-Dec-15 2015_12 ENSDARG00000022853(LOC798087) WBGene00010386(H12D21.10) ENSXETG00000016165(C3orf64) ENSMUSG00000035245(A130022J15Rik) ENSG00000163378(C3orf64) FBgn0054056 CG34056 http://flybase.net/reports/FBgn0054056.html FBgn0035175 protein_coding_gene "0048531=beta-1,3-galactosyltransferase activity" 0006486=protein glycosylation 0016020=membrane "dC1GalT6, CG13904, CG13904-1" IPR003378=Fringe-like CG34056 16-Dec-15 2015_12 viable DRSC08374 K -1.091978318 -0.12304542 -0.725386361 -0.103073032 1.689179205 -0.025373903 FBgn0010580 l(2)04535b lethal (2) 04535b http://flybase.net/reports/FBgn0010580.html gene l(2)04535 16-Dec-15 2015_12 "lethal,recessive" FBgn0043998 Su(rst)C478 Su(rst)C478 http://flybase.net/reports/FBgn0043998.html gene 0001745=compound eye morphogenesis C478 16-Dec-15 2015_12 viable FBgn0005297 mei-B meiotic B http://flybase.net/reports/FBgn0005297.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,female,recessive,fertile,poor" FBgn0020606 anon-34Da anon-34Da http://flybase.net/reports/FBgn0020606.html gene cDNA 7 16-Dec-15 2015_12 FBgn0259826 ifm(2)RS10 indirect flight muscle (2) RS10 http://flybase.net/reports/FBgn0259826.html gene 0007527=adult somatic muscle development 16-Dec-15 2015_12 viable indirect flight muscle FBgn0002208 l(3)67BDf lethal (3) 67BDf http://flybase.net/reports/FBgn0002208.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0034598 CG4266 http://flybase.net/reports/FBgn0034598.html protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0000398=mRNA splicing, via spliceosome" cg4266 "IPR006903=RNA polymerase II-binding domain, IPR000504=RNA recognition motif domain, IPR008942=ENTH/VHS, IPR006569=CID domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG4266 16-Dec-15 2015_12 WBGene00017004(nrd-1) ENSXETG00000013132(RBM16) "ENSMUSG00000046201(Rbm16),ENSMUSG00000022983(Srsf15)" "ENSG00000213079(SCAF8),ENSG00000156304(SCAF4)" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0260282 GSd478 http://flybase.net/reports/FBgn0260282.html gene 16-Dec-15 2015_12 lethal FBgn0023069 l(1)20Ah lethal (1) 20Ah http://flybase.net/reports/FBgn0023069.html gene 6-Dec 16-Dec-15 2015_12 "lethal,recessive" FBgn0265803 CR44592 http://flybase.net/reports/FBgn0265803.html non_protein_coding_gene Mgn00375 CR44592 16-Dec-15 2015_12 FBgn0044375 anon-AE003825.1 anon-AE003825.1 http://flybase.net/reports/FBgn0044375.html gene 16-Dec-15 2015_12 FBgn0031050 Arp10 Actin-related protein 10 http://flybase.net/reports/FBgn0031050.html protein_coding_gene "0003779=actin binding, 0005200=structural constituent of cytoskeleton" "0007018=microtubule-based movement, 0007010=cytoskeleton organization" "0005869=dynactin complex, 0005884=actin filament" "Arp11, CG12235, ARP11" "IPR027127=Actin-related protein 10, IPR004000=Actin family" CG12235 16-Dec-15 2015_12 ENSDARG00000038432 WBGene00016793(C49H3.8) ENSXETG00000011980(ACTR10) ENSMUSG00000021076(Actr10) ENSG00000131966(ACTR10) "lethal,recessive,partially lethal - majority die,visible" mesothoracic tergum FBgn0042160 CG18837 http://flybase.net/reports/FBgn0042160.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083992 Mkp MAP kinase-specific phosphatase http://flybase.net/reports/FBgn0083992.html "FBgn0015764, FBan0007042, FBgn0035105" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0017017=MAP kinase tyrosine/serine/threonine phosphatase activity" "0006470=protein dephosphorylation, 0000188=inactivation of MAPK activity" "CG7042, MKP, mkp, CG34099, DMKP, MAP kinase phosphatase" "IPR000340=Dual specificity phosphatase, catalytic domain, IPR024950=Dual specificity phosphatase, IPR020422=Dual specificity protein phosphatase domain, IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain" CG34099 16-Dec-15 2015_12 "ENSDARG00000045200(zgc:76883),ENSDARG00000040490(dusp19)" "YIL113W(SDP1),YNL053W(MSG5)" WBGene00021867(Y54F10BM.13) ENSXETG00000001336(dusp19) ENSMUSG00000027001(Dusp19) ENSG00000162999(DUSP19) "viable,fertile" FBgn0037744 CG8417 http://flybase.net/reports/FBgn0037744.html protein_coding_gene "0008270=zinc ion binding, 0004476=mannose-6-phosphate isomerase activity" "0005975=carbohydrate metabolic process, 0009298=GDP-mannose biosynthetic process" "IPR014710=RmlC-like jelly roll fold, IPR016305=Mannose-6-phosphate isomerase, IPR011051=RmlC-like cupin domain, IPR001250=Mannose-6-phosphate isomerase, type I, IPR018050=Phosphomannose isomerase, type I, conserved site" CG8417 16-Dec-15 2015_12 ENSDARG00000030786(zgc:110773) YER003C(PMI40) WBGene00014013(ZK632.4) ENSXETG00000021131(MPI) ENSMUSG00000032306(Mpi) ENSG00000178802(MPI) "viable,fertile" DRSC16417 K 0.032044333 -0.721649006 -0.376776952 0.478878772 0.204585862 -1.539098019 FBgn0085472 CG34443 http://flybase.net/reports/FBgn0085472.html "FBan0030070, FBgn0033930, FBgn0050070" protein_coding_gene CG30070 IPR006631=Protein of unknown function DM4/12 CG34443 16-Dec-15 2015_12 FBgn0041605 cpx complexin http://flybase.net/reports/FBgn0041605.html "FBan0032490, FBgn0052490, FBgn0063217, FBgn0063605, FBgn0064822, FBgn0064830" protein_coding_gene "0005326=neurotransmitter transporter activity, 0019905=syntaxin binding" "0051124=synaptic growth at neuromuscular junction, 0046928=regulation of neurotransmitter secretion, 0007274=neuromuscular synaptic transmission, 0016079=synaptic vesicle exocytosis, 0050804=regulation of synaptic transmission" "0005829=cytosol, 0043195=terminal bouton, 0016020=membrane, 0048786=presynaptic active zone, 0031594=neuromuscular junction" "BcDNA:RH31085, Cpx, BcDNA:GH27718, Complexin, BcDNA:RH26459, dmCplx, CG32490, DmCpx, BcDNA:HL04936" IPR008849=Synaphin CG32490 16-Dec-15 2015_12 "ENSDARG00000018997(cplx2),ENSDARG00000061918" WBGene00022271(cpx-1) "ENSXETG00000022315(Q68FB0_XENTR),ENSXETG00000007163()" "ENSMUSG00000025867(Cplx2),ENSMUSG00000033615(Cplx1)" ENSG00000145920(CPLX2) "partially lethal,uncoordinated,neurophysiology defective,viable,fertile,heat sensitive,visible,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,sterile,wild-type" "embryonic/larval neuromuscular junction | third instar larval stage,adult neuromuscular junction,embryonic/larval neuromuscular junction,mesothoracic tergum" FBgn0266687 CR45177 http://flybase.net/reports/FBgn0266687.html non_protein_coding_gene CR45177 16-Dec-15 2015_12 FBgn0263934 esn espinas http://flybase.net/reports/FBgn0263934.html "FBgn0028642, FBgn0029086, FBgn0033143, FBgn0033142" protein_coding_gene 0008270=zinc ion binding 0070593=dendrite self-avoidance "CG12833, Espinas, Dm_2R:11728, CG12835, CG43722" "IPR010442=PET domain, IPR001781=Zinc finger, LIM-type" CG43722 16-Dec-15 2015_12 "ENSDARG00000037593(prickle2),ENSDARG00000045694(prickle1b),ENSDARG00000040649(prickle1a),ENSDARG00000020982(zgc:152958)" WBGene00022727(prkl-1) "ENSXETG00000006535(PRICKLE2),ENSXETG00000006797(prickle1)" "ENSMUSG00000030020(Prickle2),ENSMUSG00000036158(Prickle1),ENSMUSG00000031145(Prickle3)" "ENSG00000163637(PRICKLE2),ENSG00000139174(PRICKLE1),ENSG00000012211(PRICKLE3)" FBgn0002802 ms(1)19Fa male sterile (1) 19Fa http://flybase.net/reports/FBgn0002802.html gene ms(1)D 16-Dec-15 2015_12 "male sterile,recessive" FBgn0025503 l(3)73Ak lethal (3) 73Ak http://flybase.net/reports/FBgn0025503.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051697 CG31697 http://flybase.net/reports/FBgn0051697.html FBgn0032802 protein_coding_gene CG10355 CG31697 16-Dec-15 2015_12 viable FBgn0060665 l(3)S080707a lethal (3) S080707a http://flybase.net/reports/FBgn0060665.html gene 0807/07 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0024542 Neos Neosin http://flybase.net/reports/FBgn0024542.html FBgn0027902 protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome "l(3)L2249, BcDNA:HL05936, BcDNA.HL05936, CG8614" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain, IPR004154=Anticodon-binding" CG8614 16-Dec-15 2015_12 ENSDARG00000016345 ENSXETG00000019514(RALY) "ENSG00000179172(HNRNPCL1),ENSG00000092199(HNRNPC),ENSG00000184672(RALYL),ENSG00000125970(RALY),ENSG00000204253" "lethal,recessive,viable" DRSC11235 I 2.321832856 1.378441246 0.627364268 0.071544028 -0.693101126 -1.086718639 FBgn0065209 l(2)SH2263 lethal (2) SH2263 http://flybase.net/reports/FBgn0065209.html gene l(2)SH2 2263 16-Dec-15 2015_12 "lethal,recessive" FBgn0016866 l(2)39ADd lethal (2) 39ADd http://flybase.net/reports/FBgn0016866.html gene H221 16-Dec-15 2015_12 lethal FBgn0035057 CG3880 http://flybase.net/reports/FBgn0035057.html protein_coding_gene "IPR026831=Adenomatous polyposis coli domain, IPR026828=Suppressor APC domain-containing protein 1/2" CG3880 16-Dec-15 2015_12 ENSMUSG00000026955(2010317E24Rik) ENSG00000186193(C9orf140) viable FBgn0082994 snoRNA:ë¬28S-1837c snoRNA:ë¬28S-1837c http://flybase.net/reports/FBgn0082994.html snoRNA_gene "Psi28S-1837c, psi28S-1837c, CR34638" CR34638 16-Dec-15 2015_12 FBgn0023545 CG4406 http://flybase.net/reports/FBgn0023545.html protein_coding_gene "0008233=peptidase activity, 0003923=GPI-anchor transamidase activity" "0016255=attachment of GPI anchor to protein, 0006508=proteolysis" 0042765=GPI-anchor transamidase complex "EG:133E12.3, cg4406" "IPR028361=GPI-anchor transamidase, IPR001096=Peptidase C13, legumain" CG4406 16-Dec-15 2015_12 ENSDARG00000024479(pigk) YDR331W(GPI8) WBGene00011482(T05E11.6) ENSXETG00000002970(PIGK) ENSMUSG00000039047(Pigk) ENSG00000142892(PIGK) FBgn0002602 M(2)44C Minute (2) 44C http://flybase.net/reports/FBgn0002602.html gene M(2)38b 16-Dec-15 2015_12 FBgn0011033 l(3)s2681 lethal (3) s2681 http://flybase.net/reports/FBgn0011033.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0051155 Rpb7 Rpb7 http://flybase.net/reports/FBgn0051155.html "FBgn0038305, FBgn0063635" protein_coding_gene "0005515=protein binding, 0003899=DNA-directed RNA polymerase activity, 0003676=nucleic acid binding" 0006366=transcription from RNA polymerase II promoter "0005665=DNA-directed RNA polymerase II, core complex" "CG6572, RPB7, dRpb7, CG31155" "IPR022967=RNA-binding domain, S1, IPR005576=RNA polymerase Rpb7, N-terminal, IPR003029=S1 domain, IPR012340=Nucleic acid-binding, OB-fold" CG31155 16-Dec-15 2015_12 ENSDARG00000056127(polr2gl) YDR404C(RPB7) WBGene00021845(rpb-7) ENSXETG00000006022(polr2g) ENSMUSG00000071662(Polr2g) ENSG00000168002(POLR2G) "viable,fertile,lethal" DRSC16068 IEK 2.650413799 3.198140773 -1.997283187 -2.38056349 2.423196075 1.066874048 FBgn0040365 CG14628 http://flybase.net/reports/FBgn0040365.html FBgn0029558 protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" "cg14628, EG:BACR42I17.12" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG14628 16-Dec-15 2015_12 viable FBgn0267817 CR46142 http://flybase.net/reports/FBgn0267817.html non_protein_coding_gene CR46142 16-Dec-15 2015_12 FBgn0003943 Ubi-p63E Ubiquitin-63E http://flybase.net/reports/FBgn0003943.html protein_coding_gene 0031386=protein tag "0010992=ubiquitin homeostasis, 0007141=male meiosis I, 0006909=phagocytosis, 0035096=larval midgut cell programmed cell death, 0048515=spermatid differentiation, 0016567=protein ubiquitination, 0006914=autophagy" 0005875=microtubule associated complex "Ubiquitin 63E, Ub, ubiquitin, Ubiquitin-polymeric, Ubiquitin-63-E, Ubi63p, polyubiquitin, Ubi-P63e, Ubiquitin, magellan, Ubi-p, UB, Ubiq, DmUb, Ubi63E, magn, ubi, ubi63E, ubi-p63E, DmUbi-p63E, Ubip63E, CG11624, Ubip, Ubp" "IPR019956=Ubiquitin, IPR000626=Ubiquitin domain, IPR019954=Ubiquitin conserved site, IPR029071=Ubiquitin-related domain" CG11624 16-Dec-15 2015_12 ENSDARG00000002369(ubb) YLL039C(UBI4) WBGene00006727(ubq-1) ENSXETG00000017136(TEgg052p01.1) ENSMUSG00000008348(Ubc) ENSG00000150991(UBC) " embryonic stage -- adult stage , embryonic stage && larval stage && pupal stage "

"increased cell death,viable,fertile,male sterile,meiotic cell cycle defective,male limited,female fertile,cell autonomous,somatic clone" "testis,spermatocyte,cell autonomous,somatic clone" DRSC08703 IEK -2.616524024 -5.089831517 -0.197005128 -7.250994117 -7.566134038 -5.573509512 FBgn0036227 CG17826 http://flybase.net/reports/FBgn0036227.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG17826 16-Dec-15 2015_12 WBGene00010351(cbd-1) viable FBgn0243516 Vrp1 Verprolin 1 http://flybase.net/reports/FBgn0243516.html "FBgn0034695, FBgn0086255" protein_coding_gene 0051015=actin filament binding "0007286=spermatid development, 0030838=positive regulation of actin filament polymerization, 0030833=regulation of actin filament polymerization, 0007015=actin filament organization, 0007522=visceral muscle development, 0007520=myoblast fusion, 0008360=regulation of cell shape, 0048149=behavioral response to ethanol" "0005737=cytoplasm, 0032433=filopodium tip" "sltr, Verprolin, dWIP, solas, D-WASp-interacting protein, D-WIP, verprolin, vrp1, WIP, WASP-interacting protein, Verprolin1, solitary, WASp Interacting Protein, verprolin 1, WASp interacting protein, CG13503, veroprolin, Solitary, Drosophila WIP, wip, Dm_Vrp1" "IPR028293=Verprolin, IPR003124=WH2 domain" CG13503 16-Dec-15 2015_12 "ENSXETG00000027599(WIPF2),ENSXETG00000008476(WIPF1),ENSXETG00000012051()" DRSC04148 I 0.547844328 -1.546639217 -1.340155535 -0.557923259 0.103537673 -0.36560665 FBgn0004806 fs(2)ltoRV64 female sterile (2) ltoRV64 http://flybase.net/reports/FBgn0004806.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0016024 l(3)89Bm lethal (3) 89Bm http://flybase.net/reports/FBgn0016024.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261508 CG42656 http://flybase.net/reports/FBgn0261508.html protein_coding_gene DMG8-chr3R.6.013 CG42656 16-Dec-15 2015_12 FBgn0036008 CG3408 http://flybase.net/reports/FBgn0036008.html protein_coding_gene 0046716=muscle cell cellular homeostasis "CT11439, unnamed" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG3408 16-Dec-15 2015_12 "ENSDARG00000071426(zgc:85752),ENSDARG00000067632" ENSMUSG00000020869(Lrrc59) ENSG00000108829(LRRC59) viable FBgn0265811 CR44600 http://flybase.net/reports/FBgn0265811.html non_protein_coding_gene CR44600 16-Dec-15 2015_12 FBgn0019688 l(3)96Aa lethal (3) 96Aa http://flybase.net/reports/FBgn0019688.html gene 291.5 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0028017 l(3)S105307 lethal (3) S105307 http://flybase.net/reports/FBgn0028017.html gene 1053/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0051494 tRNA:CR31494 transfer RNA:CR31494 http://flybase.net/reports/FBgn0051494.html "FBgn0011874, FBgn0060211" tRNA_gene "0033463=GGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:G:84C, tRNA:gly:84C, tRNA:G:TCC:AE002699-b, transfer RNA:gly:84C, tRNA[Gly][[GGA]], CR31494, chr3R.trna4-GlyTCC, AE002699.trna11-GlyTCC" CR31494 16-Dec-15 2015_12 FBgn0039078 CG4374 http://flybase.net/reports/FBgn0039078.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG4374 16-Dec-15 2015_12 YOR113W(AZF1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264750 CG44008 http://flybase.net/reports/FBgn0264750.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0032504=multicellular organism reproduction, 0010466=negative regulation of peptidase activity" 0005615=extracellular space "CG42325, CG31758" IPR002350=Kazal domain CG44008 16-Dec-15 2015_12 FBgn0085532 CG40894 http://flybase.net/reports/FBgn0085532.html FBan0040894 protein_coding_gene 16-Dec-15 2015_12 FBgn0005301 mot-32l mottled 32l http://flybase.net/reports/FBgn0005301.html gene 16-Dec-15 2015_12 "eye color defective,female,temperature conditional" "pigment cell,temperature conditional" FBgn0263289 scrib scribbled http://flybase.net/reports/FBgn0263289.html "FBgn0261263, FBgn0026178, FBgn0011401, FBgn0016016, FBgn0016937, FBgn0026234, FBgn0028155, FBgn0028975, FBgn0039432, FBgn0069188, FBgn0039433, FBgn0051082" protein_coding_gene 0005515=protein binding "0035088=establishment or maintenance of apical/basal cell polarity, 0072089=stem cell proliferation, 0050680=negative regulation of epithelial cell proliferation, 0001738=morphogenesis of a polarized epithelium, 0000902=cell morphogenesis, 0016335=morphogenesis of larval imaginal disc epithelium, 0048863=stem cell differentiation, 0008285=negative regulation of cell proliferation, 0045571=negative regulation of imaginal disc growth, 0045186=zonula adherens assembly, 0045198=establishment of epithelial cell apical/basal polarity, 0072002=Malpighian tubule development, 0016331=morphogenesis of embryonic epithelium, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0016333=morphogenesis of follicular epithelium, 0016336=establishment or maintenance of polarity of larval imaginal disc epithelium, 0007280=pole cell migration, 0008105=asymmetric protein localization, 0007472=wing disc morphogenesis, 0030100=regulation of endocytosis, 0007464=R3/R4 cell fate commitment, 0050803=regulation of synapse structure or activity, 0048749=compound eye development, 0051726=regulation of cell cycle, 0007391=dorsal closure, 0008283=cell proliferation, 0042067=establishment of ommatidial planar polarity, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0001737=establishment of imaginal disc-derived wing hair orientation, 0016334=establishment or maintenance of polarity of follicular epithelium, 0042048=olfactory behavior, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0019991=septate junction assembly, 0008406=gonad development" "0016323=basolateral plasma membrane, 0005918=septate junction, 0045169=fusome, 0031594=neuromuscular junction, 0016328=lateral plasma membrane, 0016327=apicolateral plasma membrane" "lethal (3) c00119, Scribbled, l(3)673, CG31082, Scribbles, ird15, l(3)c00119, CG5467, smell impaired 97B, smi97B, CG5462, l(3)S042405, Scrib, unnamed, Scb, vart, scrb, 0424/05, ird, scribble, Scribble, MENE (3R)-F, CG42614, CG43398, immune response deficient 15, vartul, SCR, Scrb, CT17324, gp150-like, l(3)j7B3" "IPR003591=Leucine-rich repeat, typical subtype, IPR001478=PDZ domain, IPR001611=Leucine-rich repeat, IPR016313=Disks large 1" CG43398 16-Dec-15 2015_12 ENSDARG00000000861(scrib) WBGene00002632(let-413) ENSMUSG00000022568(Scrib) ENSG00000180900(SCRIB) " adult stage | female , adult stage , pupal stage , adult stage | male , larval stage | female , larval stage | male , embryonic stage | 0-24hr , embryonic stage | 0-6hr , larval stage , embryonic stage | 9-22hr , embryonic stage | late " " antennal segment 3

, antennal segment 2

, maxillary palpus

, adult brain | restricted

, organism

, Johnston's organ

" " embryonic stage | stage 16,17 , embryonic stage | stage 15,16 , embryonic stage | late , embryonic stage | 0-12hr , embryonic stage | mid-late , embryonic stage | early , adult stage , embryonic stage | mid , embryonic stage | stage 16-17 , embryonic stage | 12-24hr " " ventral nerve cord commissure

, pole cell

, cell body

, ventral nerve cord

, ventral midline

, embryonic sensory system

, embryonic peripheral nervous system

,

ubiquitous , protocerebrum

, neuroblast

, neuron

, longitudinal connective

, antenna

, embryonic central nervous system

, maxillary palpus

, gonad

, adult brain | restricted

" FBgn0265381 CR44322 http://flybase.net/reports/FBgn0265381.html non_protein_coding_gene CR44322 16-Dec-15 2015_12 FBgn0266769 CR45234 http://flybase.net/reports/FBgn0266769.html non_protein_coding_gene lincRNA.599 CR45234 16-Dec-15 2015_12 FBgn0042164 CG18844 http://flybase.net/reports/FBgn0042164.html protein_coding_gene 16-Dec-15 2015_12 FBgn0261556 CG42674 http://flybase.net/reports/FBgn0261556.html "FBgn0036946, FBgn0052223, FBgn0259679, FBgn0036944, FBgn0036943" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0008360=regulation of cell shape, 0035025=positive regulation of Rho protein signal transduction, 0007155=cell adhesion, 0007480=imaginal disc-derived leg morphogenesis" "CG7323, CG13811, CG13812, CG42348, CG32223" "IPR000219=Dbl homology (DH) domain, IPR001849=Pleckstrin homology domain" CG42674 16-Dec-15 2015_12 "ENSG00000090924(PLEKHG2),ENSG00000120278(PLEKHG1),ENSG00000126822(PLEKHG3)" DRSC29701 K -0.325217914 0.709144588 -0.223212133 0.24194284 1.769260906 0.753322761 FBgn0085599 CG41284 http://flybase.net/reports/FBgn0085599.html FBan0041284 protein_coding_gene 0019028=viral capsid "IPR004302=Chitin-binding, domain 3" CG41284 16-Dec-15 2015_12 FBgn0028279 l(1)G0419 lethal (1) G0419 http://flybase.net/reports/FBgn0028279.html gene 16-Dec-15 2015_12 "lethal,melanotic mass phenotype,recessive" melanotic mass FBgn0065593 l(2)SH0896 lethal (2) SH0896 http://flybase.net/reports/FBgn0065593.html gene l(2)SH2 0896 16-Dec-15 2015_12 "lethal,recessive" FBgn0038153 Ir87a Ionotropic receptor 87a http://flybase.net/reports/FBgn0038153.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG14376, IR87a, DmelIR87a, ionotropic receptor 87a" CG14376 16-Dec-15 2015_12 FBgn0054001 CG34001 http://flybase.net/reports/FBgn0054001.html FBgn0082865 protein_coding_gene 0005875=microtubule associated complex "BP1041, unnamed" IPR018607=Chromosome transmission fidelity protein 8 CG34001 16-Dec-15 2015_12 ENSDARG00000069045(si:ch211-218c6.5) WBGene00011915(T22C1.4) ENSXETG00000021948(TNeu080p20.1) FBgn0270924 zf30C zinc finger protein 30C http://flybase.net/reports/FBgn0270924.html "FBgn0022720, FBgn0019699, FBgn0025984, FBgn0259301" protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" 0048666=neuron development 0005634=nucleus "C282, Zinc finger protein 30C, l(2)k02506, zf30c, CG3998, anon-EST:Liang-1.52, Zn30C, Zf30c, clone 1.52" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG3998 16-Dec-15 2015_12 DRSC03641 I -0.618223147 -1.88228469 -1.255933617 1.201817881 -0.564299946 -0.416789385 FBgn0029681 CG15239 http://flybase.net/reports/FBgn0029681.html protein_coding_gene CG15239 16-Dec-15 2015_12 DRSC17972 IE 1.669979836 3.148961189 2.900650034 0.31237846 -0.541279407 0.611735101 FBgn0053262 CG33262 http://flybase.net/reports/FBgn0053262.html protein_coding_gene unnamed IPR006631=Protein of unknown function DM4/12 CG33262 16-Dec-15 2015_12 viable DRSC22893 E 0.304340266 0.131397568 0.453693319 -1.573998141 -0.393832035 0.219280077 FBgn0035674 CG13295 http://flybase.net/reports/FBgn0035674.html protein_coding_gene "IPR027989=Domain of unknown function DUF4461, IPR027986=T-cell activation inhibitor, mitochondrial, IPR028031=Domain of unknown function DUF4460" CG13295 16-Dec-15 2015_12 WBGene00016438(C35B8.3) ENSXETG00000005361(C3orf23) ENSMUSG00000046603(D9Ertd402e) ENSG00000179152(C3orf23) "viable,fertile" FBgn0016647 ER3-5 ER3-5 http://flybase.net/reports/FBgn0016647.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266194 J29 http://flybase.net/reports/FBgn0266194.html gene 16-Dec-15 2015_12 FBgn0032149 CG4036 http://flybase.net/reports/FBgn0032149.html protein_coding_gene "0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" "0055114=oxidation-reduction process, 0035167=larval lymph gland hemopoiesis" "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR027450=Alpha-ketoglutarate-dependent dioxygenase AlkB-like" CG4036 16-Dec-15 2015_12 ENSDARG00000052247(si:dkey-261j4.10) WBGene00017304(F09F7.7) ENSXETG00000005474(ALKBH4) ENSMUSG00000039754(Alkbh4) ENSG00000160993(ALKBH4) viable FBgn0034295 CG10911 http://flybase.net/reports/FBgn0034295.html FBgn0044661 protein_coding_gene anon-WO0140519.211 IPR007931=Protein of unknown function DUF725 CG10911 16-Dec-15 2015_12 FBgn0013229 E(var)181 E(var)181 http://flybase.net/reports/FBgn0013229.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0010180 tu(2)59h tu(2)59h http://flybase.net/reports/FBgn0010180.html gene 16-Dec-15 2015_12 melanotic mass phenotype FBgn0002356 l(3)87Ec lethal (3) 87Ec http://flybase.net/reports/FBgn0002356.html gene "l(3)c9a, l(3)C9a, c9a, C9a" 16-Dec-15 2015_12 "non-enhancer of variegation,non-suppressor of variegation,lethal,recessive" FBgn0033204 CG2065 http://flybase.net/reports/FBgn0033204.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG2065 16-Dec-15 2015_12 "ENSDARG00000045277(rdh12l),ENSDARG00000018069(rdh12),ENSDARG00000068474(si:dkey-94e7.2),ENSDARG00000058966(zgc:112332),ENSDARG00000071660,ENSDARG00000008491(LOC407663),ENSDARG00000054797(zgc:153441)" YOR246C() WBGene00000985(dhs-22) ENSXETG00000008385(rdh13) ENSMUSG00000008435(Rdh13) ENSG00000160439(RDH13) viable DRSC21328 K 0.274157004 0.931060458 -0.21244034 0.435516919 1.524758674 -1.117257957 FBgn0260107 2L2806 http://flybase.net/reports/FBgn0260107.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0265105 CR44207 http://flybase.net/reports/FBgn0265105.html non_protein_coding_gene CR44207 16-Dec-15 2015_12 FBgn0002187 l(3)62Da lethal (3) 62Da http://flybase.net/reports/FBgn0002187.html gene "dre10, l(3)Da, l(3)dre10" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029172 Fad2 Fad2 http://flybase.net/reports/FBgn0029172.html FBgn0036113 protein_coding_gene 0004768=stearoyl-CoA 9-desaturase activity "0000281=mitotic cytokinesis, 0007619=courtship behavior, 0055114=oxidation-reduction process, 0006629=lipid metabolic process, 0006909=phagocytosis, 0042810=pheromone metabolic process" "desatF-alpha, fad2, desatF, CG7923, fad" "IPR005804=Fatty acid desaturase domain, IPR001522=Fatty acid desaturase, type 1, C-terminal, IPR015876=Fatty acid desaturase, type 1, core" CG7923 16-Dec-15 2015_12 "ENSDARG00000033662(scd),ENSDARG00000030265(scdb)" YGL055W(OLE1) "WBGene00001398(fat-6),WBGene00001399(fat-7),WBGene00001397(fat-5)" ENSXETG00000023757(BC096632.1) "ENSMUSG00000037071(Scd1),ENSMUSG00000025203(Scd2),ENSMUSG00000025202(Scd3),ENSMUSG00000050195(Scd4)" "ENSG00000099194(SCD),ENSG00000145284(SCD5)" "viable,visible,courtship behavior defective,mating defective" "trichogen cell,supernumerary,tormogen cell" DRSC11165 EK -0.152125597 -1.494320768 0.558777411 -2.763099657 -3.609312831 -2.579902426 FBgn0043550 Tsp68C Tetraspanin 68C http://flybase.net/reports/FBgn0043550.html FBgn0052136 protein_coding_gene "0030097=hemopoiesis, 0046331=lateral inhibition" "0048471=perinuclear region of cytoplasm, 0005802=trans-Golgi network, 0016021=integral component of membrane" "Dm.Tsp68C, unnamed, CG32136" "IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG32136 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,supernumerary,trichogen cell,tormogen cell,lamellocyte,embryonic/larval hemocyte" FBgn0031116 CG1695 http://flybase.net/reports/FBgn0031116.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity "IPR004012=RUN domain, IPR000195=Rab-GTPase-TBC domain" CG1695 16-Dec-15 2015_12 "ENSDARG00000028857(LOC794373),ENSDARG00000063307" WBGene00008018(tbc-8) "ENSXETG00000018672(SGSM1),ENSXETG00000019436(SGSM2)" ENSMUSG00000042216(Sgsm1) ENSG00000167037(SGSM1) viable FBgn0023009 l(3)S101804 lethal (3) S101804 http://flybase.net/reports/FBgn0023009.html gene "1018/04, unnamed" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0034841 CG13541 http://flybase.net/reports/FBgn0034841.html protein_coding_gene CG13541 16-Dec-15 2015_12 viable FBgn0036217 CG5906 http://flybase.net/reports/FBgn0036217.html FBgn0063324 protein_coding_gene 0016021=integral component of membrane BcDNA:AT16953 IPR007248=Mpv17/PMP22 CG5906 16-Dec-15 2015_12 ENSDARG00000056367(mpv17l2) YOR292C() ENSXETG00000018317(BC075397.1) viable FBgn0016730 Rst(2)chl Resistant to chlorpyrifos http://flybase.net/reports/FBgn0016730.html gene 16-Dec-15 2015_12 chemical resistant FBgn0045841 ë_Tub56D::ë_Tub85D ë_Tub56D::ë_Tub85D http://flybase.net/reports/FBgn0045841.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0061078 l(3)S014917b lethal (3) S014917b http://flybase.net/reports/FBgn0061078.html gene 0149/17 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0001456 l(1)7Dj lethal (1) 7Dj http://flybase.net/reports/FBgn0001456.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0013689 mt:tRNA:A mitochondrial alanine tRNA http://flybase.net/reports/FBgn0013689.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "alanine tRNA, mtdbD00006302, Dm mt tRNA[Ala], CR34077" CR34077 16-Dec-15 2015_12 FBgn0065099 snRNA:7SK small nuclear RNA 7SK http://flybase.net/reports/FBgn0065099.html FBgn0053925 snRNA_gene "7SK snRNA, chr3R:3300517..3300757, 7SK, snmRNA:331-RA, 7SK RNA, snmRNA:331, small non-messenger RNA 331, Dm-331, d7SK, CR33925" CR33925 16-Dec-15 2015_12 FBgn0037020 Pex14 Peroxin 14 http://flybase.net/reports/FBgn0037020.html protein_coding_gene "0007031=peroxisome organization, 0006625=protein targeting to peroxisome, 0016560=protein import into peroxisome matrix, docking" "0005777=peroxisome, 0005778=peroxisomal membrane" "DmelPex14, PEX14, CG4289" "IPR025655=Peroxisomal membrane protein 14, IPR006785=Peroxisome membrane anchor protein Pex14p, N-terminal" CG4289 16-Dec-15 2015_12 ENSDARG00000028322 YGL153W(PEX14) WBGene00004199(prx-14) ENSXETG00000006309(PEX14) ENSMUSG00000028975(Pex14) ENSG00000142655(PEX14) viable FBgn0036988 CG5262 http://flybase.net/reports/FBgn0036988.html FBgn0062077 protein_coding_gene anon-WO0118547.347 "IPR013057=Amino acid transporter, transmembrane domain" CG5262 16-Dec-15 2015_12 ENSDARG00000070782 WBGene00007267(C03A3.2) ENSXETG00000006842(TMEM104) ENSMUSG00000045980(Tmem104) ENSG00000109066(TMEM104) viable FBgn0037235 CG1103 http://flybase.net/reports/FBgn0037235.html "FBan0001103, FBgn0062211" protein_coding_gene anon-WO0118547.152 IPR026748=Clarin CG1103 16-Dec-15 2015_12 DRSC24616 K -2.193477536 0.118010086 FBgn0044381 anon-5.9 anon-5.9 http://flybase.net/reports/FBgn0044381.html repeat_region 16-Dec-15 2015_12 FBgn0264462 CR43870 http://flybase.net/reports/FBgn0264462.html non_protein_coding_gene CR43870 16-Dec-15 2015_12 FBgn0264256 naz nazgul http://flybase.net/reports/FBgn0264256.html protein_coding_gene 0005737=cytoplasm "Naz, Nazgul" 16-Dec-15 2015_12 FBgn0062661 EP3223 EP3223 http://flybase.net/reports/FBgn0062661.html gene EP(3)3223 16-Dec-15 2015_12 FBgn0083259 E(smoDN)871 Enhancer of smoDN 871 http://flybase.net/reports/FBgn0083259.html gene 16-Dec-15 2015_12 FBgn0053364 5SrRNA:CR33364 5SrRNA:CR33364 http://flybase.net/reports/FBgn0053364.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33364 CR33364 16-Dec-15 2015_12 FBgn0003402 Shudderer Shudderer http://flybase.net/reports/FBgn0003402.html gene Shu 16-Dec-15 2015_12 "uncoordinated,gravitaxis defective" FBgn0259247 laccase2 laccase 2 http://flybase.net/reports/FBgn0259247.html "FBgn0050437, FBgn0033022, FBgn0033023, FBgn0052838" protein_coding_gene "0005507=copper ion binding, 0052716=hydroquinone:oxygen oxidoreductase activity" "0055114=oxidation-reduction process, 0040003=chitin-based cuticle development" "CG10408, CG30437, laccase 2, CG32838, MCO2, CG10398, CG42345" "IPR011707=Multicopper oxidase, type 3, IPR011706=Multicopper oxidase, type 2, IPR001117=Multicopper oxidase, type 1, IPR008972=Cupredoxin, IPR002355=Multicopper oxidase, copper-binding site" CG42345 16-Dec-15 2015_12 "YMR058W(FET3),YFL041W(FET5)" WBGene00009008(F21D5.3) DRSC26018 K -0.480722888 0.331649162 0.434171433 0.428054987 2.307090213 0.508630512 FBgn0266158 CR44864 http://flybase.net/reports/FBgn0266158.html non_protein_coding_gene CR44864 16-Dec-15 2015_12 FBgn0083300 E(smoDN)1823 Enhancer of smoDN 1823 http://flybase.net/reports/FBgn0083300.html gene 16-Dec-15 2015_12 FBgn0061196 CG15468 http://flybase.net/reports/FBgn0061196.html FBgn0029739 protein_coding_gene "Syntaxin Interacting Protein 3, SIP3, CG15468" CG15468 16-Dec-15 2015_12 viable DRSC18051 K -0.296428581 0.483790754 -0.315684127 0.350809764 2.246247079 1.091342566 FBgn0069327 X-146-21 X-146-21 http://flybase.net/reports/FBgn0069327.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0019986 Glt::Nrt Glt::Nrt http://flybase.net/reports/FBgn0019986.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0025836 RhoGAP1A Rho GTPase activating protein at 1A http://flybase.net/reports/FBgn0025836.html FBgn0026442 protein_coding_gene "0005096=GTPase activator activity, 0005089=Rho guanyl-nucleotide exchange factor activity" "0045792=negative regulation of cell size, 0035025=positive regulation of Rho protein signal transduction, 0007030=Golgi organization" "BCR, CG40453, CG40494, CG17960, CG17617, EG:23E12.5, rhoGAP1A, EG:23E12.2, RhoGAP1A, RhoGAP" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR008936=Rho GTPase activation protein, IPR000219=Dbl homology (DH) domain, IPR000198=Rho GTPase-activating protein domain, IPR000008=C2 domain, IPR001849=Pleckstrin homology domain" CG40494 16-Dec-15 2015_12 "ENSDARG00000029096,ENSDARG00000042329(LOC560226)" "ENSMUSG00000009681(Bcr),ENSMUSG00000017631(Abr)" "ENSG00000186716(BCR),ENSG00000159842(ABR)" viable FBgn0005216 l(3)ET7 lethal Elaine Tasaka 7 http://flybase.net/reports/FBgn0005216.html gene 16-Dec-15 2015_12 "lethal,cold sensitive,heat sensitive,male sterile" FBgn0058115 CG40115 http://flybase.net/reports/FBgn0058115.html protein_coding_gene 16-Dec-15 2015_12 FBgn0058241 CG40241 http://flybase.net/reports/FBgn0058241.html protein_coding_gene 16-Dec-15 2015_12 FBgn0045855 e(Pi3K92E)gamma e(Pi3K92E)gamma http://flybase.net/reports/FBgn0045855.html gene gamma 16-Dec-15 2015_12 FBgn0002255 l(3)68Eg lethal (3) 68Eg http://flybase.net/reports/FBgn0002255.html gene "l(3)rsg17, rsg17, rose-gespleten region interval 17" 16-Dec-15 2015_12 lethal FBgn0037482 CG10055 http://flybase.net/reports/FBgn0037482.html protein_coding_gene 0022618=ribonucleoprotein complex assembly RE52393 IPR007009=SHQ1 protein CG10055 16-Dec-15 2015_12 "ENSDARG00000060186,ENSDARG00000058522(LOC100006673)" ENSMUSG00000035378(Shq1) ENSG00000144736(SHQ1) viable FBgn0033374 CG13741 http://flybase.net/reports/FBgn0033374.html FBgn0050346 protein_coding_gene CG30346 CG13741 16-Dec-15 2015_12 "visible,planar polarity defective,partially lethal - majority die,some die during pupal stage,female sterile" trichogen cell DRSC06412 K 0.335951901 0.588919752 0.262231959 0.200083419 3.851150831 1.058683071 FBgn0003272 rp rotated penis http://flybase.net/reports/FBgn0003272.html gene 16-Dec-15 2015_12 "male sterile,small body" "tergite,eye,leg,abdomen,male genitalia" FBgn0004091 l(2)60Cc lethal (2) 60Cc http://flybase.net/reports/FBgn0004091.html gene 16-Dec-15 2015_12 FBgn0005361 sx sexcombless http://flybase.net/reports/FBgn0005361.html gene 16-Dec-15 2015_12 male sterile "genitalia,clasper,penis,sex comb,macrochaeta,vulva,gonopod thorn bristle,anal plate,ovary,testis,metatarsus" FBgn0267768 CR46099 http://flybase.net/reports/FBgn0267768.html non_protein_coding_gene CR46099 16-Dec-15 2015_12 FBgn0005135 l(1)Y107 lethal (1) Y107 http://flybase.net/reports/FBgn0005135.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0001377 l(1)2Bh lethal (1) 2Bh http://flybase.net/reports/FBgn0001377.html gene "l(1)HM40, HM40" 16-Dec-15 2015_12 "lethal,recessive" FBgn0086066 snoRNA:Me5.8S-G74 http://flybase.net/reports/FBgn0086066.html snoRNA_gene "Me5.8S-Gm74, CR34695, Me5.8S-G74" CR34695 16-Dec-15 2015_12 FBgn0033467 CG15863 http://flybase.net/reports/FBgn0033467.html protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding 0016272=prefoldin complex "IPR009053=Prefoldin, IPR002777=Prefoldin beta-like, IPR030482=p53 and DNA damage-regulated protein 1" CG15863 16-Dec-15 2015_12 ENSDARG00000045017(zgc:112519) ENSXETG00000022516(Q5HZC3_XENTR) ENSMUSG00000027472(Pdrg1) ENSG00000088356(PDRG1) FBgn0267778 CR46109 http://flybase.net/reports/FBgn0267778.html non_protein_coding_gene CR46109 16-Dec-15 2015_12 FBgn0040352 CG14416 http://flybase.net/reports/FBgn0040352.html FBgn0029636 protein_coding_gene EG:BACR43E12.7 CG14416 16-Dec-15 2015_12 FBgn0065129 l(3)SH134 lethal (3) SH134 http://flybase.net/reports/FBgn0065129.html gene l(2)SH3 134 16-Dec-15 2015_12 "lethal,recessive" FBgn0267532 CR45872 http://flybase.net/reports/FBgn0267532.html non_protein_coding_gene CR45872 16-Dec-15 2015_12 FBgn0022815 E(faf)E1051 Enhancer of faf E1051 http://flybase.net/reports/FBgn0022815.html gene 16-Dec-15 2015_12 FBgn0022380 Pt-10A Adult protein-10A http://flybase.net/reports/FBgn0022380.html gene 16-Dec-15 2015_12 FBgn0065222 l(2)SH2226 lethal (2) SH2226 http://flybase.net/reports/FBgn0065222.html gene l(2)SH2 2226 16-Dec-15 2015_12 "lethal,recessive" FBgn0016764 anon-17Ca anon-17Ca http://flybase.net/reports/FBgn0016764.html gene "Transcription unit C1, C1" 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0023170 RpL39 Ribosomal protein L39 http://flybase.net/reports/FBgn0023170.html FBgn0047027 protein_coding_gene 0003735=structural constituent of ribosome "0000022=mitotic spindle elongation, 0006412=translation, 0007052=mitotic spindle organization" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "RpL46, BcDNA:RH27094, anon-EST:Posey16, Ribosomal protein L46, L39, CG3997, rp46, Rp46, RPl46" "IPR000077=Ribosomal protein L39e, IPR023626=Ribosomal protein L39e domain, IPR020083=Ribosomal protein L39e, conserved site" CG3997 16-Dec-15 2015_12 ENSDARG00000036316(rpl39) YJL189W(RPL39) WBGene00004453(rpl-39) "ENSMUSG00000079641(Rpl39),ENSMUSG00000036305,ENSMUSG00000039209(Rpl39l)" "ENSG00000214289,ENSG00000198918(RPL39),ENSG00000163923(RPL39L)" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04651 IEK -2.2505861 -2.415181306 3.139503081 -4.523638653 2.810435677 2.640578618 FBgn0010241 Mdr50 Multi drug resistance 50 http://flybase.net/reports/FBgn0010241.html "FBtr0087537, FBpp0086666" protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0042623=ATPase activity, coupled, 0015238=drug transmembrane transporter activity" "0015893=drug transport, 0031427=response to methotrexate, 0055085=transmembrane transport" "0005886=plasma membrane, 0016021=integral component of membrane" "Multi drug resistance 50, CG8523, MDR50, Dm2, Dm3, mdr50, multi-drug resistance 50" "IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG8523 16-Dec-15 2015_12 "ENSDARG00000011573,ENSDARG00000070821,ENSDARG00000070078,ENSDARG00000010936(abcb4)" YKL209C(STE6) "WBGene00004003(pgp-9),WBGene00003995(pgp-1),WBGene00003996(pgp-2)" "ENSXETG00000005990(),ENSXETG00000007433(),ENSXETG00000002493(),ENSXETG00000016210(ABCB11)" "ENSMUSG00000040584(Abcb1a),ENSMUSG00000028970(Abcb1b),ENSMUSG00000042476(Abcb4),ENSMUSG00000027048(Abcb11)" "ENSG00000085563(ABCB1),ENSG00000005471(ABCB4),ENSG00000004846(ABCB5),ENSG00000073734(ABCB11)" adult stage DRSC07467 IE 1.981677106 0.106965008 2.428400612 0.396501141 -0.250017016 0.060573317 FBgn0002908 mus311 mutagen-sensitive 311 http://flybase.net/reports/FBgn0002908.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive,female sterile,DNA repair defective" FBgn0266836 CR45298 http://flybase.net/reports/FBgn0266836.html non_protein_coding_gene CR45298 16-Dec-15 2015_12 FBgn0264430 CR43848 http://flybase.net/reports/FBgn0264430.html non_protein_coding_gene CR43848 16-Dec-15 2015_12 FBgn0060553 l(3)S097613b lethal (3) S097613b http://flybase.net/reports/FBgn0060553.html gene 0976/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0260309 GSd411 http://flybase.net/reports/FBgn0260309.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0000876 fs(1)M74 female sterile (1) M74 http://flybase.net/reports/FBgn0000876.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0261931 CG42797 http://flybase.net/reports/FBgn0261931.html "FBgn0030144, FBgn0030145" protein_coding_gene "0061630=ubiquitin protein ligase activity, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination "BT058014.1, CG3003, CG3099" "IPR001202=WW domain, IPR000569=HECT domain" CG42797 16-Dec-15 2015_12 FBgn0052625 CG32625 http://flybase.net/reports/FBgn0052625.html protein_coding_gene "IPR022776=TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG32625 16-Dec-15 2015_12 ENSDARG00000000887(zgc:56699) WBGene00020286(T06A10.3) "viable,fertile" FBgn0065421 l(2)SH1522 lethal (2) SH1522 http://flybase.net/reports/FBgn0065421.html gene l(2)SH2 1522 16-Dec-15 2015_12 "lethal,recessive" FBgn0082629 S(CycEJP)2.9 S(CycEJP)2.9 http://flybase.net/reports/FBgn0082629.html gene Complementation group 2.9 16-Dec-15 2015_12 "lethal,recessive" FBgn0040136 l(1)G0498 lethal (1) G0498 http://flybase.net/reports/FBgn0040136.html gene 16-Dec-15 2015_12 "partially lethal - majority die,male,female,lethal,recessive" FBgn0037702 CG8176 http://flybase.net/reports/FBgn0037702.html FBgn0067621 protein_coding_gene "0035612=AP-2 adaptor complex binding, 0005543=phospholipid binding" 0072583=clathrin-mediated endocytosis "0005737=cytoplasm, 0005905=coated pit, 0005886=plasma membrane" "FCHo, FCHo2, CG31123" "IPR028565=Mu homology domain, IPR031160=F-BAR domain, IPR018808=Muniscin C-terminal, IPR001060=FCH domain" CG8176 16-Dec-15 2015_12 ENSDARG00000035389(fcho2) ENSXETG00000016431(FCHO1) "ENSMUSG00000041685(Fcho2),ENSMUSG00000070000(Fcho1)" "ENSG00000157107(FCHO2),ENSG00000130475(FCHO1)" "viable,fertile,visible" tormogen cell FBgn0035942 CG5660 http://flybase.net/reports/FBgn0035942.html protein_coding_gene "0005524=ATP binding, 0002161=aminoacyl-tRNA editing activity, 0004832=valine-tRNA ligase activity" 0006438=valyl-tRNA aminoacylation mitochondrial valyl-tRNA synthetase "IPR013155=Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR009008=Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR002303=Valine-tRNA ligase, IPR002300=Aminoacyl-tRNA synthetase, class Ia, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG5660 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0011569 can cannonball http://flybase.net/reports/FBgn0011569.html FBgn0036079 protein_coding_gene 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly "0007286=spermatid development, 0010468=regulation of gene expression, 0006355=regulation of transcription, DNA-templated, 0007126=meiotic nuclear division, 0048515=spermatid differentiation, 0007283=spermatogenesis, 0007141=male meiosis I, 0006367=transcription initiation from RNA polymerase II promoter" "0005669=transcription factor TFIID complex, 0001673=male germ cell nucleus, 0005730=nucleolus" "Can, Taf5L, Cannonball, dTAF[[II]]80, dmTAF5b, TAF5L, dTAF5L, CG6577" "IPR007582=TFIID subunit, WD40-associated region, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site" CG6577 16-Dec-15 2015_12 "male sterile,recessive,meiotic cell cycle defective,viable" "testis,spermatocyte" FBgn0260764 CG42562 http://flybase.net/reports/FBgn0260764.html "FBgn0034260, FBan0014481" protein_coding_gene CG14481 CG42562 16-Dec-15 2015_12 viable FBgn0259531 B2005 http://flybase.net/reports/FBgn0259531.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment,tibia,arista" FBgn0052121 CG32121 http://flybase.net/reports/FBgn0052121.html protein_coding_gene 0046872=metal ion binding "IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR007087=Zinc finger, C2H2" CG32121 16-Dec-15 2015_12 lethal FBgn0028883 CG4959 http://flybase.net/reports/FBgn0028883.html "FBgn0040983, FBgn0063230" protein_coding_gene "BG:DS04095.3, BcDNA:GH21762, bs04e09.y1" 16-Dec-15 2015_12 DRSC01938 K 0.787960895 0.540336643 -0.685209612 0.114267074 1.8736043 0.595796613 FBgn0028578 pjc-16 pjc-16 http://flybase.net/reports/FBgn0028578.html gene 16-Dec-15 2015_12 FBgn0050110 CG30110 http://flybase.net/reports/FBgn0050110.html FBgn0045354 protein_coding_gene NEST:bs09e07 CG30110 16-Dec-15 2015_12 viable DRSC05686 I -1.529531705 -0.53450013 0.009128057 -0.174505015 -0.286136893 -0.310439807 FBgn0065362 l(2)SH1742 lethal (2) SH1742 http://flybase.net/reports/FBgn0065362.html gene l(2)SH2 1742 16-Dec-15 2015_12 "lethal,recessive" FBgn0026679 IntS4 Integrator 4 http://flybase.net/reports/FBgn0026679.html FBgn0030047 protein_coding_gene "0022008=neurogenesis, 0034472=snRNA 3'-end processing, 0016180=snRNA processing" 0032039=integrator complex "CG12113, lethal (1) G0095, l(1)G0095, Int4" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG12113 16-Dec-15 2015_12 ENSDARG00000063610(LOC564681) WBGene00012234(W04A4.5) ENSXETG00000010447(INTS4) ENSMUSG00000025133(Ints4) ENSG00000149262(INTS4) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0267464 CR45814 http://flybase.net/reports/FBgn0267464.html non_protein_coding_gene CR45814 16-Dec-15 2015_12 FBgn0004663 ms(1)10A male sterile (1) 10A http://flybase.net/reports/FBgn0004663.html "FBgn0002798, FBgn0002811" gene "locus 7, ms(1)BP6" 16-Dec-15 2015_12 male sterile axoneme FBgn0003723 tmc tonomacrochaetae http://flybase.net/reports/FBgn0003723.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" "macrochaeta,adult abdomen" FBgn0267622 CR45960 http://flybase.net/reports/FBgn0267622.html non_protein_coding_gene CR45960 16-Dec-15 2015_12 FBgn0264661 small-potatoes small potatoes http://flybase.net/reports/FBgn0264661.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0035996 CG3448 http://flybase.net/reports/FBgn0035996.html protein_coding_gene 0003677=DNA binding "0006302=double-strand break repair, 0006310=DNA recombination" 0005634=nucleus "IPR014751=DNA repair protein XRCC4, C-terminal, IPR010585=DNA repair protein XRCC4" CG3448 16-Dec-15 2015_12 viable FBgn0015547 srg semirough http://flybase.net/reports/FBgn0015547.html gene 16-Dec-15 2015_12 visible eye FBgn0005729 l(1)TK205 lethal (1) TK205 http://flybase.net/reports/FBgn0005729.html gene l205 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0037181 CG11370 http://flybase.net/reports/FBgn0037181.html protein_coding_gene CG11370 16-Dec-15 2015_12 "viable,fertile" FBgn0259841 Su(Ste):CR42410 Su(Ste):CR42410 http://flybase.net/reports/FBgn0259841.html non_protein_coding_gene CR42410 CR42410 16-Dec-15 2015_12 FBgn0001945 l(2)26Cf lethal (2) 26Cf http://flybase.net/reports/FBgn0001945.html gene l(2)gdh-13 16-Dec-15 2015_12 "lethal,recessive" FBgn0003420 slc slim chaetae http://flybase.net/reports/FBgn0003420.html gene l(1)3Ea 16-Dec-15 2015_12 "viable,fertile,visible" "macrochaeta,wing" FBgn0259457 EP-111 http://flybase.net/reports/FBgn0259457.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0264342 CG43798 http://flybase.net/reports/FBgn0264342.html protein_coding_gene lincRNA.43 CG43798 16-Dec-15 2015_12 FBgn0083011 snoRNA:ë¬28S-1135b snoRNA:ë¬28S-1135b http://flybase.net/reports/FBgn0083011.html snoRNA_gene "Psi28S-1135b, psi28S-1135b, CR34605" CR34605 16-Dec-15 2015_12 FBgn0000582 eq equational producer http://flybase.net/reports/FBgn0000582.html gene equational 16-Dec-15 2015_12 "meiotic cell cycle defective,male" FBgn0029980 CG10778 http://flybase.net/reports/FBgn0029980.html protein_coding_gene "0016765=transferase activity, transferring alkyl or aryl (other than methyl) groups" 0006909=phagocytosis "IPR018520=Di-trans-poly-cis-decaprenylcistransferase-like, conserved site, IPR001441=Decaprenyl diphosphate synthase-like" CG10778 16-Dec-15 2015_12 ENSDARG00000039851(dhdds) YBR002C(RER2) WBGene00044025(T01G1.4) ENSXETG00000012322(DHDDS) ENSMUSG00000012117(Dhdds) ENSG00000117682(DHDDS) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0003184 qf quetas finas http://flybase.net/reports/FBgn0003184.html gene quetas-finas 16-Dec-15 2015_12 "semi-sterile,viable" "microchaeta,macrochaeta" FBgn0039158 CG6182 http://flybase.net/reports/FBgn0039158.html FBgn0063155 protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity BcDNA:LD17019 IPR000195=Rab-GTPase-TBC domain CG6182 16-Dec-15 2015_12 ENSDARG00000029581(tbc1d7) ENSXETG00000001070(tbc1d7) ENSMUSG00000021368(Tbc1d7) ENSG00000145979(TBC1D7) "viable,fertile" FBgn0040268 Top3ë± Topoisomerase 3ë± http://flybase.net/reports/FBgn0040268.html FBgn0032795 protein_coding_gene "0003916=DNA topoisomerase activity, 0008270=zinc ion binding, 0003917=DNA topoisomerase type I activity, 0003677=DNA binding" "0048589=developmental growth, 0006265=DNA topological change, 0000002=mitochondrial genome maintenance, 0042246=tissue regeneration, 0000724=double-strand break repair via homologous recombination" "0005739=mitochondrion, 0005634=nucleus, 0005694=chromosome" "Topoisomerase3alpha, CG10123, Topoisomerase IIIa, top3alpha, topoisomerase 3alpha, topoisomerase IIIalpha, Topo IIIalpha, Top 3alpha, DmTop3alpha, topo IIIalpha, Topoisomerase IIIalpha, dTopoIIIa, Top3a, Topoisomerase 3-alpha, Top3alpha" "IPR006171=Toprim domain, IPR023406=DNA topoisomerase, type IA, active site, IPR000380=DNA topoisomerase, type IA, IPR001878=Zinc finger, CCHC-type, IPR003601=DNA topoisomerase, type IA, domain 2, IPR013497=DNA topoisomerase, type IA, central, IPR013826=DNA topoisomerase, type IA, central region, subdomain 3, IPR013824=DNA topoisomerase, type IA, central region, subdomain 1, IPR023405=DNA topoisomerase, type IA, core domain, IPR010666=Zinc finger, GRF-type, IPR003602=DNA topoisomerase, type IA, DNA-binding domain, IPR013498=DNA topoisomerase, type IA, zn finger" CG10123 16-Dec-15 2015_12 ENSDARG00000052827(top3a) YLR234W(TOP3) WBGene00006596(top-3) ENSXETG00000005765(TOP3A) ENSMUSG00000002814(Top3a) ENSG00000177302(TOP3A) "visible,conditional,size defective,female sterile,male sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,developmental rate defective,lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,viable,lethal,melanotic necrosis" "eye,conditional,egg,maternal effect,testis,sperm individualization complex, with Top3ë±54,imaginal disc,sperm individualization complex, with Top3ë±M1L.TAvicGFP-EYFP,melanotic mass" FBgn0032362 spz4 spatzle 4 http://flybase.net/reports/FBgn0032362.html protein_coding_gene 0005121=Toll binding 0008063=Toll signaling pathway 0005576=extracellular region "Spz4, CT34755, CG14928" IPR029034=Cystine-knot cytokine CG14928 16-Dec-15 2015_12 viable DRSC02410 IE 1.088307464 1.509271305 2.088802389 -1.519118626 0.195574073 0.08780924 FBgn0085756 CR40613 http://flybase.net/reports/FBgn0085756.html FBan0040613 rRNA_gene CR40613 16-Dec-15 2015_12 FBgn0267939 CR46219 http://flybase.net/reports/FBgn0267939.html non_protein_coding_gene lincRNA.903 CR46219 16-Dec-15 2015_12 FBgn0259282 C37 http://flybase.net/reports/FBgn0259282.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta" FBgn0063781 accord2\gag gag http://flybase.net/reports/FBgn0063781.html transposable_element_gene qbert\gag 16-Dec-15 2015_12 FBgn0005104 gusC gustatory C http://flybase.net/reports/FBgn0005104.html gene 0030536=larval feeding behavior 16-Dec-15 2015_12 taste perception defective FBgn0266384 CR45026 http://flybase.net/reports/FBgn0266384.html non_protein_coding_gene CR45026 16-Dec-15 2015_12 FBgn0260103 2L0372 http://flybase.net/reports/FBgn0260103.html gene "0035149=lumen formation, open tracheal system" 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,somatic clone" FBgn0051346 CG31346 http://flybase.net/reports/FBgn0051346.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065410 l(2)SH1570 lethal (2) SH1570 http://flybase.net/reports/FBgn0065410.html gene l(2)SH2 1570 16-Dec-15 2015_12 "lethal,recessive" FBgn0086170 nkd::Hsap\NKD2 http://flybase.net/reports/FBgn0086170.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0086210 su(comp)3L-2 http://flybase.net/reports/FBgn0086210.html gene 16-Dec-15 2015_12 FBgn0038541 TyrRII Tyramine receptor II http://flybase.net/reports/FBgn0038541.html "FBgn0046605, FBgn0046606" protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0004989=octopamine receptor activity" "0007193=adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, 0071928=tyramine signaling pathway, 0071418=cellular response to amine stimulus, 0007186=G-protein coupled receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "DmCG16766, anon-WO0170980.125, anon-WO0170980.124, CG16766" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG16766 16-Dec-15 2015_12 ENSMUSG00000027335(Adra1d) FBgn0004481 l(1)air6 lethal aberrant immune response 6 http://flybase.net/reports/FBgn0004481.html gene "l(1)air[6], air6" 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval proventriculus,foregut imaginal ring,embryonic/larval lymph gland" FBgn0034199 Gbp Growth-blocking peptide http://flybase.net/reports/FBgn0034199.html protein_coding_gene 0005125=cytokine activity "0009611=response to wounding, 0034112=positive regulation of homotypic cell-cell adhesion, 0043647=inositol phosphate metabolic process, 0045926=negative regulation of growth, 0061057=peptidoglycan recognition protein signaling pathway, 0002775=antimicrobial peptide production, 0051482=positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway" 0005615=extracellular space "growth-blocking peptide, GBP, growth-blocking peptide-like factor, CG15917" CG15917 16-Dec-15 2015_12 "developmental rate defective,immune response defective,stress response defective,viable" FBgn0267456 CR45806 http://flybase.net/reports/FBgn0267456.html non_protein_coding_gene CR45806 16-Dec-15 2015_12 FBgn0052280 CG32280 http://flybase.net/reports/FBgn0052280.html FBgn0047260 protein_coding_gene BcDNA:GM08588 IPR006629=LPS-induced tumour necrosis factor alpha factor CG32280 16-Dec-15 2015_12 ENSDARG00000052666(litaf) WBGene00009484(F36G3.3) ENSXETG00000024896(litaf) ENSMUSG00000004071(5730403B10Rik) ENSG00000089486(C16orf5) "viable,fertile" FBgn0260023 veguero veguero http://flybase.net/reports/FBgn0260023.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0031377 CG15356 http://flybase.net/reports/FBgn0031377.html protein_coding_gene "0005875=microtubule associated complex, 0070822=Sin3-type complex, 0005634=nucleus" EMSY IPR005491=EMSY N-terminal CG15356 16-Dec-15 2015_12 ENSDARG00000059059(zgc:56039) ENSXETG00000019422(C11orf30) ENSMUSG00000035401(2210018M11Rik) ENSG00000158636(C11orf30) FBgn0000694 flrdR flight reduced R http://flybase.net/reports/FBgn0000694.html gene flrd-R 16-Dec-15 2015_12 "hypoactive,flight defective" FBgn0052252 CR32252 http://flybase.net/reports/FBgn0052252.html FBgn0063309 non_protein_coding_gene "BcDNA:AT23419, CG32252" CR32252 16-Dec-15 2015_12 viable FBgn0259857 Su(Ste):CR42426 Su(Ste):CR42426 http://flybase.net/reports/FBgn0259857.html non_protein_coding_gene CR42426 CR42426 16-Dec-15 2015_12 FBgn0003017 ot outheld http://flybase.net/reports/FBgn0003017.html gene l(1)19Ab 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced,lethal" "wing,ocellar bristle,microchaeta,microchaeta & adult thorax" FBgn0038872 Nelf-A Negative elongation factor A http://flybase.net/reports/FBgn0038872.html FBgn0064781 protein_coding_gene 0003723=RNA binding "0007070=negative regulation of transcription from RNA polymerase II promoter during mitosis, 0034244=negative regulation of transcription elongation from RNA polymerase II promoter" "0005634=nucleus, 0017053=transcriptional repressor complex, 0032021=NELF complex" "NELF, NELF-A, BcDNA:SD07139, CG5874" IPR026305=Negative elongation factor A CG5874 16-Dec-15 2015_12 "small body,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,lethal" FBgn0032082 CG18088 http://flybase.net/reports/FBgn0032082.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi21430616, gi7297472" "IPR004245=Protein of unknown function DUF229, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain" CG18088 16-Dec-15 2015_12 viable FBgn0030868 CG12986 http://flybase.net/reports/FBgn0030868.html protein_coding_gene CG12986 16-Dec-15 2015_12 "viable,visible,planar polarity defective" trichogen cell FBgn0069339 UY1844 UY1844 http://flybase.net/reports/FBgn0069339.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0262991 CR43299 http://flybase.net/reports/FBgn0262991.html non_protein_coding_gene CR43299 16-Dec-15 2015_12 FBgn0021795 Tapë« Translocon-associated protein ë« http://flybase.net/reports/FBgn0021795.html "FBgn0027912, FBgn0064943" protein_coding_gene 0005048=signal sequence binding 0006621=protein retention in ER lumen "0016021=integral component of membrane, 0005784=Sec61 translocon complex, 0012505=endomembrane system, 0005811=lipid particle, 0005786=signal recognition particle, endoplasmic reticulum targeting" "l(2)k17005, CG9035, TRAPdelta, BcDNA:GM12291, Translocon-associated protein delta, Tapdelta" IPR008855=Translocon-associated CG9035 16-Dec-15 2015_12 ENSDARG00000019444(ssr4) WBGene00013238(trap-4) ENSXETG00000000730(SSR4) ENSMUSG00000002014(Ssr4) ENSG00000180879(SSR4) "lethal,recessive,viable" embryonic/larval salivary gland FBgn0264905 CR44096 http://flybase.net/reports/FBgn0264905.html non_protein_coding_gene lincRNA.827 CR44096 16-Dec-15 2015_12 FBgn0070013 BG01228 BG01228 http://flybase.net/reports/FBgn0070013.html gene 16-Dec-15 2015_12 stress response defective FBgn0033820 CG4716 http://flybase.net/reports/FBgn0033820.html FBgn0043820 protein_coding_gene 0004486=methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity "Dmel_CG4716, gh18008, BEST:GH18008, GH16" CG4716 16-Dec-15 2015_12 viable FBgn0028078 l(3)S086405 lethal (3) S086405 http://flybase.net/reports/FBgn0028078.html gene 0864/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0013542 l(2)A1-2-12 lethal (2) A1-2-12 http://flybase.net/reports/FBgn0013542.html gene 16-Dec-15 2015_12 lethal FBgn0053831 His1:CG33831 His1:CG33831 http://flybase.net/reports/FBgn0053831.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33831 "IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15" CG33831 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0060760 l(3)S063319 lethal (3) S063319 http://flybase.net/reports/FBgn0060760.html gene 0633/19 16-Dec-15 2015_12 "lethal,recessive" FBgn0029147 NtR NtR http://flybase.net/reports/FBgn0029147.html "FBgn0034698, FBgn0044797" protein_coding_gene "0005231=excitatory extracellular ligand-gated ion channel activity, 0005230=extracellular ligand-gated ion channel activity" 0006811=ion transport 0016021=integral component of membrane "CG6698, DNtR, anon-WO0138359.3" "IPR022041=Farnesoic acid O-methyl transferase, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain" CG6698 16-Dec-15 2015_12 viable FBgn0265455 CG44355 http://flybase.net/reports/FBgn0265455.html protein_coding_gene CG44355 16-Dec-15 2015_12 FBgn0083268 E(smoDN)391 Enhancer of smoDN 391 http://flybase.net/reports/FBgn0083268.html gene 16-Dec-15 2015_12 FBgn0037845 CG14694 http://flybase.net/reports/FBgn0037845.html protein_coding_gene 0008518=reduced folate carrier activity 0006810=transport 0016020=membrane "IPR020846=Major facilitator superfamily domain, IPR002666=Reduced folate carrier" CG14694 16-Dec-15 2015_12 "ENSDARG00000059712(LOC100329244),ENSDARG00000061103(slc19a3),ENSDARG00000006447(LOC557854)" "WBGene00018138(folt-2),WBGene00044738(folt-3)" "ENSXETG00000002422(SLC19A2),ENSXETG00000008390(TGas049p21.1),ENSXETG00000014773(BC075531.1),ENSXETG00000011482(SLC19A1)" "ENSMUSG00000038496(Slc19a3),ENSMUSG00000040918(Slc19a2)" "ENSG00000117479(SLC19A2),ENSG00000135917(SLC19A3),ENSG00000173638(SLC19A1)" viable FBgn0065308 l(2)SH1963 lethal (2) SH1963 http://flybase.net/reports/FBgn0065308.html gene l(2)SH2 1963 16-Dec-15 2015_12 "lethal,recessive" FBgn0038233 HtrA2 HTRA2-related serine protease http://flybase.net/reports/FBgn0038233.html protein_coding_gene "0008233=peptidase activity, 0005515=protein binding, 0004252=serine-type endopeptidase activity" "0007005=mitochondrion organization, 0043065=positive regulation of apoptotic process, 0007283=spermatogenesis, 2001056=positive regulation of cysteine-type endopeptidase activity, 0035234=ectopic germ cell programmed cell death, 0042981=regulation of apoptotic process" "0005829=cytosol, 0005739=mitochondrion, 0016006=Nebenkern, 0005758=mitochondrial intermembrane space" "dOmi, Serine protease HTRA2, HtrA2/Omi, domi, DmHtrA2, CG8464, omi, htrA2, htrA2/omi, Omi, HtrA2" "IPR001940=Peptidase S1C, IPR001478=PDZ domain, IPR009003=Peptidase S1, PA clan" CG8464 16-Dec-15 2015_12 "ENSDARG00000069877(LOC100149563),ENSDARG00000069921,ENSDARG00000069911,ENSDARG00000069845,ENSDARG00000069854,ENSDARG00000069909(LOC100330375),ENSDARG00000068819(zgc:174193),ENSDARG00000068810,ENSDARG00000068795,ENSDARG00000069903,ENSDARG00000069862,ENSDARG00000014907(htra1b),ENSDARG00000069858,ENSDARG00000032831(htra1a),ENSDARG00000005943(LOC100334257),ENSDARG00000069885,ENSDARG00000069896" "ENSXETG00000015580(HTRA1),ENSXETG00000015154(HTRA4)" "ENSMUSG00000068329(Htra2),ENSMUSG00000029096(Htra3)" "ENSG00000115317(HTRA2),ENSG00000170801(HTRA3),ENSG00000166033(HTRA1)" "viable,fertile,radiation resistant,chemical resistant,visible,heat sensitive,male sterile,partially lethal - majority die,male fertile,decreased cell death,female fertile,dominant,flightless,locomotor behavior defective,short lived,chemical sensitive" "eye | pupal stage,eye,heat sensitive,indirect flight muscle,spermatid cyst,investment coneED5644),male germline cell,spermatogonial cyst,mitochondrion & indirect flight muscle,spermatozoon" FBgn0005116 l(1)ff lethal (1) formalin food http://flybase.net/reports/FBgn0005116.html gene Lff11 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval pharynx,embryonic brain,embryonic segment,embryonic/first instar larval cuticle,dorsal" FBgn0067911 GS(2)A096 GS(2)A096 http://flybase.net/reports/FBgn0067911.html gene 16-Dec-15 2015_12 lethal "ventral nerve cord commissure,longitudinal connective,RP1 motor neuron,lateral longitudinal fascicle" FBgn0036161 CG7551 http://flybase.net/reports/FBgn0036161.html FBgn0063754 protein_coding_gene "0008865=fructokinase activity, 0004454=ketohexokinase activity" 0046835=carbohydrate phosphorylation 0005737=cytoplasm BcDNA:AT07524 "IPR029056=Ribokinase-like, IPR011611=Carbohydrate kinase PfkB" CG7551 16-Dec-15 2015_12 ENSDARG00000029874(khk) ENSXETG00000001220(KHK) ENSMUSG00000029162(Khk) ENSG00000138030(KHK) FBgn0040544 CG14700 http://flybase.net/reports/FBgn0040544.html protein_coding_gene 16-Dec-15 2015_12 FBgn0050223 tRNA:H:56E transfer RNA:his:56E http://flybase.net/reports/FBgn0050223.html FBgn0060208 tRNA_gene 0033426=CAC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA[His], AE002787.trna9-HisGTG, tRNA:CR30223, tRNA:his:56E, CR30223, tRNA:H:GTG:AE002787-a, chr2R.trna67-HisGTG, transfer RNA:CR30223" CR30223 16-Dec-15 2015_12 FBgn0039058 VhaAC39-2 Vacuolar H+ ATPase AC39 subunit 2 http://flybase.net/reports/FBgn0039058.html FBgn0062158 protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0015078=hydrogen ion transmembrane transporter activity" 0015991=ATP hydrolysis coupled proton transport "0000220=vacuolar proton-transporting V-type ATPase, V0 domain, 0033176=proton-transporting V-type ATPase complex, 0033179=proton-transporting V-type ATPase, V0 domain" "Vacuolar H[+] ATPase subunit AC39-2, CG4624, vhaAC39-2, anon-WO0118547.227" "IPR016727=ATPase, V0 complex, subunit d, IPR002843=ATPase, V0 complex, c/d subunit" CG4624 16-Dec-15 2015_12 YLR447C(VMA6) viable FBgn0015789 Rab10 Rab10 http://flybase.net/reports/FBgn0015789.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0007295=growth of a germarium-derived egg chamber, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport, 0045175=basal protein localization, 0046331=lateral inhibition" "0031982=vesicle, 0055037=recycling endosome, 0005737=cytoplasm, 0031254=cell trailing edge, 0045178=basal part of cell, 0045202=synapse, 0043025=neuronal cell body" "Rab-r10, DRAB10, AAF50924, DRab10, CG17060, Rab-protein 10, rab10, DmRab10, O15971" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type" CG17060 16-Dec-15 2015_12 ENSDARG00000046106(zgc:92757) YFL005W(SEC4) WBGene00004273(rab-10) ENSMUSG00000020671(Rab10) ENSG00000084733(RAB10) "visible,body color defective,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,mesothoracic tergum,egg" FBgn0065843 l(2)SH0321 lethal (2) SH0321 http://flybase.net/reports/FBgn0065843.html gene l(2)SH2 0321 16-Dec-15 2015_12 "lethal,recessive" FBgn0040780 Atg10 Autophagy-related 10 http://flybase.net/reports/FBgn0040780.html protein_coding_gene 0019777=Atg12 transferase activity "0016236=macroautophagy, 0006464=cellular protein modification process" "Autophagy-specific gene 10, ATG10, CG12821, Atg10" IPR007135=Autophagy-related protein 3 CG12821 16-Dec-15 2015_12 ENSDARG00000040149(atg10) WBGene00008427(atg-10) ENSMUSG00000021619(Atg10) ENSG00000152348(ATG10) FBgn0027957 l(3)S148011a lethal (3) S148011a http://flybase.net/reports/FBgn0027957.html gene "l(3)S148011, 1480/11" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0265049 CR44164 http://flybase.net/reports/FBgn0265049.html non_protein_coding_gene CR44164 16-Dec-15 2015_12 FBgn0000538 eb extra bristles http://flybase.net/reports/FBgn0000538.html gene 16-Dec-15 2015_12 "visible,recessive" "macrochaeta & scutum,scutellar bristle" FBgn0283460 mir-10404 mir-10404 stem loop http://flybase.net/reports/FBgn0283460.html miRNA_gene 0035195=gene silencing by miRNA mir-10404/mir-ITS1 16-Dec-15 2015_12 FBgn0262623 CG43147 http://flybase.net/reports/FBgn0262623.html protein_coding_gene lincRNA.541 CG43147 16-Dec-15 2015_12 FBgn0050213 CR30213 http://flybase.net/reports/FBgn0050213.html "FBgn0050136, FBgn0050139" non_protein_coding_gene "CR30139, CR30136" 16-Dec-15 2015_12 FBgn0262293 mir-2490 mir-2490 stem loop http://flybase.net/reports/FBgn0262293.html miRNA_gene "dme-mir-2490, CR43000" CR43000 16-Dec-15 2015_12 viable FBgn0040832 CG8012 http://flybase.net/reports/FBgn0040832.html FBgn0063219 protein_coding_gene BcDNA:GH26995 CG8012 16-Dec-15 2015_12 viable FBgn0002304 l(3)84Cb lethal (3) 84Cb http://flybase.net/reports/FBgn0002304.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027962 l(3)S145710a lethal (3) S145710a http://flybase.net/reports/FBgn0027962.html FBgn0060501 gene "0479/06, l(3)S145710, 1067/10, l(3)S106710a" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038641 CG7708 http://flybase.net/reports/FBgn0038641.html protein_coding_gene "0015171=amino acid transmembrane transporter activity, 0015220=choline transmembrane transporter activity, 0005298=proline:sodium symporter activity" "0003333=amino acid transmembrane transport, 0008292=acetylcholine biosynthetic process" 0016021=integral component of membrane dSLC5A15 IPR001734=Sodium/solute symporter CG7708 16-Dec-15 2015_12 ENSDARG00000060912(LOC799259) WBGene00000501(cho-1) ENSXETG00000010384(SLC5A7) ENSMUSG00000023945(Slc5a7) ENSG00000115665(SLC5A7) viable FBgn0030003 CG2116 http://flybase.net/reports/FBgn0030003.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" 0048813=dendrite morphogenesis "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG2116 16-Dec-15 2015_12 "ENSDARG00000042667(klf2a),ENSDARG00000040432(klf2b),ENSDARG00000038792(klf4),ENSDARG00000017400(klfd)" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB,abdominal ventral multidendritic neuron v'dap" FBgn0011284 RpS4 Ribosomal protein S4 http://flybase.net/reports/FBgn0011284.html FBgn0025296 protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" "0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0006412=translation, 0051297=centrosome organization, 0051298=centrosome duplication" "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "Rp S4, CG11276, SX4, RPS4, anon-EST:Posey270, rpS4" "IPR000876=Ribosomal protein S4e, IPR002942=RNA-binding S4 domain, IPR005824=KOW, IPR013843=Ribosomal protein S4e, N-terminal, IPR013845=Ribosomal protein S4e, central region, IPR018199=Ribosomal protein S4e, N-terminal, conserved site" CG11276 16-Dec-15 2015_12 ENSDARG00000014690(rps4x) "YHR203C(RPS4B),YJR145C(RPS4A)" WBGene00004473(rps-4) ENSXETG00000027073(rps4x) "ENSMUSG00000031320(Rps4x),ENSMUSG00000044609(Gm9294),ENSMUSG00000063171,ENSMUSG00000046411(Gm6816)" "ENSG00000198034(RPS4X),ENSG00000129824(RPS4Y1),ENSG00000157828(RPS4Y2)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC11272 EK -0.82511944 -0.274034651 0.15711297 -3.774973909 1.255007503 3.195982836 FBgn0001493 l(1)10Bg lethal (1) 10Bg http://flybase.net/reports/FBgn0001493.html gene "10Bg, l(1)GLM20, l(1)G20" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect,lethal" "ovariole,germline clone,egg,egg chamber,maternal effect,macrochaeta" FBgn0014930 CG2846 http://flybase.net/reports/FBgn0014930.html protein_coding_gene 0008531=riboflavin kinase activity "0009398=FMN biosynthetic process, 0009231=riboflavin biosynthetic process" "transcript C, C, unnamed, anon-84Ea" "IPR023468=Riboflavin kinase, IPR023465=Riboflavin kinase domain, IPR015865=Riboflavin kinase domain, bacterial/eukaryotic" CG2846 16-Dec-15 2015_12 ENSDARG00000060522(si:dkey-162f21.5) YDR236C(FMN1) WBGene00011224(R10H10.6) ENSXETG00000000759(RFK) ENSMUSG00000024712(Rfk) ENSG00000135002(RFK) DRSC15454 I 1.514014056 0.622911737 0.207042151 0.017693266 0.653123358 -0.238126751 FBgn0034071 CG8405 http://flybase.net/reports/FBgn0034071.html protein_coding_gene 0048190=wing disc dorsal/ventral pattern formation membralin IPR019144=Membralin CG8405 16-Dec-15 2015_12 ENSMUSG00000013858(ORF61) ENSG00000182087(C19orf6) viable FBgn0265675 CR44482 http://flybase.net/reports/FBgn0265675.html non_protein_coding_gene CR44482 16-Dec-15 2015_12 FBgn0266830 CR45292 http://flybase.net/reports/FBgn0266830.html non_protein_coding_gene CR45292 16-Dec-15 2015_12 FBgn0002128 l(2)K201 lethal (2) K201 http://flybase.net/reports/FBgn0002128.html gene 16-Dec-15 2015_12 lethal FBgn0060469 l(3)S112803 lethal (3) S112803 http://flybase.net/reports/FBgn0060469.html gene 1128/03 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0261635 CG42718 http://flybase.net/reports/FBgn0261635.html protein_coding_gene CG42718 16-Dec-15 2015_12 FBgn0050332 CG30332 http://flybase.net/reports/FBgn0050332.html FBgn0063321 protein_coding_gene BcDNA:AT17896 16-Dec-15 2015_12 FBgn0016636 E(gl)3D Enhancer of glass 3D http://flybase.net/reports/FBgn0016636.html gene 16-Dec-15 2015_12 "lethal,recessive" presumptive embryonic/larval central nervous system FBgn0264701 CR43970 http://flybase.net/reports/FBgn0264701.html non_protein_coding_gene CR43970 16-Dec-15 2015_12 FBgn0061472 3R-I256 3R-I256 http://flybase.net/reports/FBgn0061472.html gene 16-Dec-15 2015_12 "neuron,somatic clone" FBgn0030109 CG12121 http://flybase.net/reports/FBgn0030109.html protein_coding_gene 0016021=integral component of membrane "IPR009637=Transmembrane receptor, eukaryota" CG12121 16-Dec-15 2015_12 ENSDARG00000069067 WBGene00015801(C15H9.5) ENSXETG00000001356(GPR107) "ENSMUSG00000005823(Gpr108),ENSMUSG00000000194(Gpr107)" "ENSG00000125734(GPR108),ENSG00000148358(GPR107)" FBgn0260576 MENE-WW14 http://flybase.net/reports/FBgn0260576.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0032101 CG9586 http://flybase.net/reports/FBgn0032101.html protein_coding_gene CG9586 16-Dec-15 2015_12 ENSDARG00000054446(ccdc43) ENSXETG00000003386(CCDC43) ENSMUSG00000020925(Ccdc43) ENSG00000180329(CCDC43) viable FBgn0054005 CG34005 http://flybase.net/reports/FBgn0054005.html FBgn0082887 protein_coding_gene "BP1019, unnamed" IPR007931=Protein of unknown function DUF725 CG34005 16-Dec-15 2015_12 FBgn0261846 CG42778 http://flybase.net/reports/FBgn0261846.html protein_coding_gene lincRNA.767 CG42778 16-Dec-15 2015_12 FBgn0040375 CG13760 http://flybase.net/reports/FBgn0040375.html FBgn0029625 protein_coding_gene EG:BACR25B3.6 IPR018616=Guanylyl cyclase CG13760 16-Dec-15 2015_12 ENSDARG00000068438(zgc:152874) ENSXETG00000004230(TEgg075i13.1) ENSMUSG00000033416(1110038D17Rik) ENSG00000138867(C22orf13) "viable,visible" mesothoracic tergum FBgn0010217 ATPsynë_ "ATP synthase, ë_ subunit" http://flybase.net/reports/FBgn0010217.html protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism, 0005524=ATP binding" "0015991=ATP hydrolysis coupled proton transport, 0015992=proton transport, 0015986=ATP synthesis coupled proton transport, 0046331=lateral inhibition" "0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), 0005811=lipid particle, 0005739=mitochondrion" "ATPsyn-&bgr, ATPB, F1ATP synthase, ATP synthase Beta chain, ATPase beta, Comp V beta, beta-ATPase, ATP synthase beta chain, ATP SYNTHASE BETA CHAIN, Complex V beta, ATP synthase, ATPsyn-b, ATPsyn-beta, F0/F1 ATP synthase Beta, ATPsyn b, ATP-syn-B, ATP, CG11154, H+-ATPase beta subunit, ATP synthase subunit beta, mitochondrial, ATP syn-beta, ATP-synbeta, ATP synthase beta, ATP synthase beta subunit, ATP synthase subunit beta, ATPasebeta, ATP synthase subunits beta, beta-F1-ATPase, ATP synthase-beta" "IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR024034=ATPase, F1 complex beta subunit/V1 complex, C-terminal, IPR005722=ATPase, F1 complex, beta subunit, IPR003593=AAA+ ATPase domain, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site" CG11154 16-Dec-15 2015_12 "ENSDARG00000070819(wu:fj55c09),ENSDARG00000070083(zgc:111961)" YJR121W(ATP2) WBGene00000229(atp-2) ENSXETG00000024665(atp5b) ENSMUSG00000025393(Atp5b) ENSG00000110955(ATP5B) "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,female sterile,RU486 conditional,short lived,female,visible,partially lethal - majority die" "wing,adult thorax,chaeta" DRSC17194 K -0.919309664 0.132514835 -0.378673279 -0.049979443 1.08050153 2.743133277 FBgn0014941 anon-98Db anon-98Db http://flybase.net/reports/FBgn0014941.html gene unnamed 16-Dec-15 2015_12 FBgn0069325 X-156-10 X-156-10 http://flybase.net/reports/FBgn0069325.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0032934 CG8679 http://flybase.net/reports/FBgn0032934.html protein_coding_gene dLEM3 "IPR011015=LEM/LEM-like domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR003887=LEM domain" CG8679 16-Dec-15 2015_12 ENSDARG00000069894 WBGene00002276(lem-3) ENSXETG00000006436(ANKLE1) ENSMUSG00000046295(Ankle1) ENSG00000160117(ANKLE1) viable FBgn0085578 CG41252 http://flybase.net/reports/FBgn0085578.html FBan0041252 protein_coding_gene 16-Dec-15 2015_12 FBgn0001848 l(1)ts4975 lethal (1) ts4975 http://flybase.net/reports/FBgn0001848.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0016815 l(1)L18 lethal (1) L18 http://flybase.net/reports/FBgn0016815.html gene L18 16-Dec-15 2015_12 "lethal,recessive" FBgn0033973 HPS1 Hermansky-Pudlak Syndrome 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0033973.html protein_coding_gene "0006909=phagocytosis, 0060967=negative regulation of gene silencing by RNA" 0031085=BLOC-3 complex "NP_610997, dHPS1, HPS, CG12855, Hermansky-Pudlak Syndrome 1 ortholog" IPR026053=Hermansky-Pudlak syndrome 1 protein CG12855 16-Dec-15 2015_12 ENSDARG00000026170(hps1) ENSMUSG00000025188(Hps1) ENSG00000107521(HPS1) viable FBgn0032489 CG15480 http://flybase.net/reports/FBgn0032489.html protein_coding_gene CG15480 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum DRSC02490 K -0.236220433 0.176035602 0.442982596 0.092155641 -0.699332014 -1.574464581 FBgn0025583 IM2 Immune induced molecule 2 http://flybase.net/reports/FBgn0025583.html "FBgn0034332, FBgn0044675, FBgn0047046" protein_coding_gene "0006952=defense response, 0009617=response to bacterium" 0005576=extracellular region "anon-WO0140519.2, Immune-induced molecule 2, immune induced peptide 2, immune induced molecule 2, BcDNA:RH08291, CG18106, DIM-2, Immune-induced peptide 2 precursor, Immune molecule 2, DIM2, DIM 2, Im2" IPR013172=Immune-induced protein Dim CG18106 16-Dec-15 2015_12 adult stage viable FBgn0034473 Or56a Odorant receptor 56a http://flybase.net/reports/FBgn0034473.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" 0007608=sensory perception of smell "0032590=dendrite membrane, 0016021=integral component of membrane" "odorant receptor 56a, 56a, 56E.1, DOR59, CG12501" "IPR004117=Olfactory receptor, Drosophila" CG12501 16-Dec-15 2015_12 viable FBgn0267241 CR45681 http://flybase.net/reports/FBgn0267241.html non_protein_coding_gene CR45681 16-Dec-15 2015_12 FBgn0262430 mir-9c mir-9c stem loop http://flybase.net/reports/FBgn0262430.html "FBgn0067678, FBgn0262278" miRNA_gene 0007281=germ cell development "mir-9c, mir-9, CR42985, CR33564, miR-9c, miR-9, 9c, dme-mir-9c, MiR-9c, mir-9C, dme-miR-9c-5p" CR42985 16-Dec-15 2015_12 embryonic stage -- adult stage "lethal,visible" "eye,wing,wing margin,wing margin bristle,germline cell,maternal effect" FBgn0024499 Acprep1 Accessory gland protein rep1 http://flybase.net/reports/FBgn0024499.html gene Acp rep1 16-Dec-15 2015_12 FBgn0259458 EP-654a http://flybase.net/reports/FBgn0259458.html gene 16-Dec-15 2015_12 visible wing FBgn0030598 CG9503 http://flybase.net/reports/FBgn0030598.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity, 0016614=oxidoreductase activity, acting on CH-OH group of donors" "0055114=oxidation-reduction process, 0045455=ecdysteroid metabolic process" Dm GMCalpha1 "IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR012132=Glucose-methanol-choline oxidoreductase" CG9503 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) FBgn0008647 S63 S63 http://flybase.net/reports/FBgn0008647.html gene S 63 16-Dec-15 2015_12 FBgn0044099 E(rst)C6 E(rst)C6 http://flybase.net/reports/FBgn0044099.html gene 0001745=compound eye morphogenesis C6 16-Dec-15 2015_12 viable eye FBgn0025920 l(3)78Ae lethal (3) 78Ae http://flybase.net/reports/FBgn0025920.html gene 16-Dec-15 2015_12 lethal FBgn0002786 mot-36e mottled 36e http://flybase.net/reports/FBgn0002786.html gene 16-Dec-15 2015_12 "female sterile,visible,eye color defective" "pigment cell,wing,wing vein,posterior crossvein,macrochaeta,microchaeta" FBgn0039735 Nph Nucleophosmin http://flybase.net/reports/FBgn0039735.html protein_coding_gene "0003676=nucleic acid binding, 0042393=histone binding" "0006338=chromatin remodeling, 0035041=sperm chromatin decondensation" "0005634=nucleus, 0005737=cytoplasm" "Nucleoplasmin, nucleophosmin, CG7911" "IPR004301=Nucleoplasmin, IPR024057=Nucleoplasmin core domain" CG7911 16-Dec-15 2015_12 "ENSDARG00000053963(npm2),ENSDARG00000071886,ENSDARG00000056794(npm3)" "ENSXETG00000014472(npm3),ENSXETG00000008403(npm1),ENSXETG00000010542(npm2),ENSXETG00000016499()" "ENSMUSG00000047911(Npm2),ENSMUSG00000057113(Npm1),ENSMUSG00000056209(Npm3)" "ENSG00000107833(NPM3),ENSG00000158806(NPM2)" FBgn0000092 CG2650 http://flybase.net/reports/FBgn0000092.html protein_coding_gene 0007623=circadian rhythm 0005615=extracellular space "0.9 gene, EG:155E2.1, anonymous 0.9 kb RNA, 0.9, 0.9kb transcript, anon-3B1.2, unnamed" IPR010562=Haemolymph juvenile hormone binding CG2650 16-Dec-15 2015_12 " adult stage , pupal stage " " epidermis

, epidermis

{ 0 per* } " viable FBgn0014350 ms(2)HB40 ms(2)HB40 http://flybase.net/reports/FBgn0014350.html gene 16-Dec-15 2015_12 FBgn0041737 l(3)63Ef lethal (3) 63Ef http://flybase.net/reports/FBgn0041737.html gene group I 16-Dec-15 2015_12 lethal FBgn0036819 Dysb Dysbindin ortholog (H. sapiens) http://flybase.net/reports/FBgn0036819.html protein_coding_gene 0005515=protein binding "1900073=regulation of neuromuscular synaptic transmission, 0008057=eye pigment granule organization, 0008344=adult locomotory behavior, 0007616=long-term memory, 0008355=olfactory learning, 0048167=regulation of synaptic plasticity, 0045963=negative regulation of dopamine metabolic process, 0007614=short-term memory, 0050807=regulation of synapse organization, 0051968=positive regulation of synaptic transmission, glutamatergic, 0048047=mating behavior, sex discrimination" "0008021=synaptic vesicle, 0031083=BLOC-1 complex, 0098527=neuromuscular junction of somatic muscle" "CG6856, dysb, dysbindin, NP_649064, Dysbindin, Ddysb" IPR007531=Dysbindin CG6856 16-Dec-15 2015_12 ENSDARG00000055115(dtnbp1a) ENSXETG00000015432(DBNDD2) ENSMUSG00000057531(Dtnbp1) ENSG00000047579(DTNBP1) "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,courtship behavior defective,eye color defective,viable,visible,memory defective,recessive,locomotor behavior defective" "embryonic/larval neuromuscular junction | larval stage,trichogen cell,embryonic/larval neuromuscular junction" FBgn0053543 CG33543 http://flybase.net/reports/FBgn0053543.html "FBgn0031382, FBgn0031383, FBtr0077864, FBpp0077533, FBtr0077865, FBpp0077534" protein_coding_gene 0007155=cell adhesion 0016020=membrane "CT35364, 33543, CG15354, CT35363, CG15355" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013151=Immunoglobulin" CG33543 16-Dec-15 2015_12 viable FBgn0039551 Or98a Odorant receptor 98a http://flybase.net/reports/FBgn0039551.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "98a, DOR110, 98B.1, Or98A, CG5540, DmOr98a" "IPR004117=Olfactory receptor, Drosophila" CG5540 16-Dec-15 2015_12 viable FBgn0038268 CG3631 http://flybase.net/reports/FBgn0038268.html protein_coding_gene 0004672=protein kinase activity 0006468=protein phosphorylation "0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "IPR009581=FAM20, C-terminal, IPR024869=FAM20" CG3631 16-Dec-15 2015_12 ENSXETG00000022814(fam20b) "viable,fertile" FBgn0053017 CG33017 http://flybase.net/reports/FBgn0053017.html "FBgn0034101, FBgn0034102" protein_coding_gene "CG15702, CG15703" IPR006578=MADF domain CG33017 16-Dec-15 2015_12 viable FBgn0003641 su(wh) suppressor of white-honey http://flybase.net/reports/FBgn0003641.html gene suppressor of white honey 16-Dec-15 2015_12 FBgn0028156 l(3)S042228 lethal (3) S042228 http://flybase.net/reports/FBgn0028156.html gene 0422/28 16-Dec-15 2015_12 "lethal,recessive" FBgn0265177 CG44242 http://flybase.net/reports/FBgn0265177.html FBgn0034089 protein_coding_gene CG8446 "IPR020373=Ribosomal protein S36, mitochondrial" CG44242 16-Dec-15 2015_12 "viable,fertile" FBgn0005165 l(2)G559 lethal (2) G559 http://flybase.net/reports/FBgn0005165.html gene 16-Dec-15 2015_12 lethal FBgn0050211 tRNA:CR30211 transfer RNA:CR30211 http://flybase.net/reports/FBgn0050211.html "FBgn0050146, FBgn0060012" tRNA_gene 0033416=UGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna59-TrpCCA, tRNA:W:CCA:AE002787-a, CR30146, AE002787.trna1-TrpCCA, CR30211" CR30211 16-Dec-15 2015_12 FBgn0266142 CR44848 http://flybase.net/reports/FBgn0266142.html non_protein_coding_gene CR44848 16-Dec-15 2015_12 FBgn0025121 su(RpII140Z36)S7 su(RpII140Z36)S7 http://flybase.net/reports/FBgn0025121.html gene Z36[S7] 16-Dec-15 2015_12 FBgn0030904 upd2 unpaired 2 http://flybase.net/reports/FBgn0030904.html protein_coding_gene "0040018=positive regulation of multicellular organism growth, 0007379=segment specification, 0046427=positive regulation of JAK-STAT cascade, 0038001=paracrine signaling, 0060729=intestinal epithelial structure maintenance" "cg5988, Upd2/Leptin, UPD2, upd homolog, Upd-like, Unpaired2, Upd2, CG5988" CG5988 16-Dec-15 2015_12 "viable,fertile,immune response defective,recessive,small body,decreased cell number,decreased cell size" "wing,embryonic/larval oenocyte" FBgn0266118 suffix\ORF http://flybase.net/reports/FBgn0266118.html transposable_element_gene 16-Dec-15 2015_12 FBgn0027084 Aats-lys Lysyl-tRNA synthetase http://flybase.net/reports/FBgn0027084.html FBgn0030143 protein_coding_gene "0004824=lysine-tRNA ligase activity, 0003676=nucleic acid binding, 0005524=ATP binding" 0006430=lysyl-tRNA aminoacylation "0005875=microtubule associated complex, 0005737=cytoplasm, 0017101=aminoacyl-tRNA synthetase multienzyme complex" "KRS, CG12141, LysRS" "IPR002313=Lysine-tRNA ligase, class II, IPR018149=Lysyl-tRNA synthetase, class II, C-terminal, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR004365=OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004364=Aminoacyl-tRNA synthetase, class II (D/K/N), IPR012340=Nucleic acid-binding, OB-fold, IPR018150=Aminoacyl-tRNA synthetase, class II (D/K/N)-like" CG12141 16-Dec-15 2015_12 ENSDARG00000044220(kars) YDR037W(KRS1) WBGene00002238(kars-1) ENSXETG00000003569(kars) ENSMUSG00000031948(Kars) ENSG00000065427(KARS) embryonic stage "

ubiquitous , embryonic/larval salivary gland

" FBgn0266625 CR45132 http://flybase.net/reports/FBgn0266625.html non_protein_coding_gene CR45132 16-Dec-15 2015_12 FBgn0061103 l(3)S008702 lethal (3) S008702 http://flybase.net/reports/FBgn0061103.html "FBgn0060536, FBgn0060581, FBgn0060690, FBgn0060726" gene "l(3)S068002b, l(3)S094713, 0680/02, 1004/09, 0087/02, l(3)S008702b, l(3)S100409b, 0737/04, l(3)S073704b, 0947/13" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0083298 E(smoDN)1835 Enhancer of smoDN 1835 http://flybase.net/reports/FBgn0083298.html gene 16-Dec-15 2015_12 FBgn0001261 inaB inactivation no afterpotential B http://flybase.net/reports/FBgn0001261.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0014194 hyl hyl http://flybase.net/reports/FBgn0014194.html gene 16-Dec-15 2015_12 FBgn0085702 CG41576 http://flybase.net/reports/FBgn0085702.html FBan0041576 protein_coding_gene 16-Dec-15 2015_12 FBgn0050418 nord nord http://flybase.net/reports/FBgn0050418.html "FBgn0034993, FBgn0034995, FBgn0063642" protein_coding_gene "0008355=olfactory learning, 0007611=learning or memory" "E3272, CG13574, CG30418, CG3372" "IPR003961=Fibronectin type III, IPR019326=Protein of unknown function DUF2369" CG30418 16-Dec-15 2015_12 ENSDARG00000062936 WBGene00021893(Y54G2A.29) "ENSXETG00000002103(C4orf31),ENSXETG00000003099(),ENSXETG00000015829()" ENSMUSG00000049001(A930038C07Rik) ENSG00000173376(NDNF) "learning defective,memory defective,viable" FBgn0041130 l(2)45Af lethal (2) 45Af http://flybase.net/reports/FBgn0041130.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0004096 l(2)60Dd lethal (2) 60Dd http://flybase.net/reports/FBgn0004096.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0060462 l(3)S115510a lethal (3) S115510a http://flybase.net/reports/FBgn0060462.html gene 16-Dec-15 2015_12 lethal FBgn0267965 CR46245 http://flybase.net/reports/FBgn0267965.html non_protein_coding_gene Dm_X:36005 CR46245 16-Dec-15 2015_12 FBgn0069445 E(br)444 E(br)444 http://flybase.net/reports/FBgn0069445.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,semidominant" leg FBgn0003191 ra rase http://flybase.net/reports/FBgn0003191.html gene 16-Dec-15 2015_12 viable "head bristle,scutellar bristle,macrochaeta,microchaeta,thorax,head" FBgn0034506 CG13870 http://flybase.net/reports/FBgn0034506.html protein_coding_gene CG13870 16-Dec-15 2015_12 viable FBgn0035761 RhoGEF4 Rho guanine nucleotide exchange factor 4 http://flybase.net/reports/FBgn0035761.html protein_coding_gene "0005089=Rho guanyl-nucleotide exchange factor activity, 0004871=signal transducer activity" "0008360=regulation of cell shape, 0035025=positive regulation of Rho protein signal transduction, 0051496=positive regulation of stress fiber assembly" "0005737=cytoplasm, 0005634=nucleus" "RhoGEF4, DRhoGEF4, RhoGEF, CG8606" "IPR000219=Dbl homology (DH) domain, IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG8606 16-Dec-15 2015_12 ENSDARG00000013476(zgc:103517) WBGene00006476(rhgf-2) "viable,fertile" FBgn0058265 CG40265 http://flybase.net/reports/FBgn0058265.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040795 CG13038 http://flybase.net/reports/FBgn0040795.html protein_coding_gene CG13038 16-Dec-15 2015_12 viable FBgn0024698 Cpsf160 Cleavage and polyadenylation specificity factor 160 http://flybase.net/reports/FBgn0024698.html "FBgn0024812, FBgn0033941, FBgn0062164" protein_coding_gene "0003730=mRNA 3'-UTR binding, 0017022=myosin binding, 0003729=mRNA binding" "0006379=mRNA cleavage, 0022008=neurogenesis, 0006378=mRNA polyadenylation" 0005847=mRNA cleavage and polyadenylation specificity factor complex "Cpsf, CPSF, CG10110, anon-WO0118547.217, cleavage and polyadenylation specificity factor, CPSF-160, cpsf, Drosophila cleavage and polyadenylation stimulation factor-160, dCPSF-160, CPSF160" "IPR004871=Cleavage/polyadenylation specificity factor, A subunit, C-terminal" CG10110 16-Dec-15 2015_12 ENSDARG00000034178(cpsf1) YDR301W(CFT1) WBGene00022301(cpsf-1) ENSMUSG00000034022(Cpsf1) ENSG00000071894(CPSF1) " embryonic stage--pupal stage , adult stage | male , adult stage | female " "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "hypostomal sclerite,embryonic/first instar larval cuticle,embryonic/larval neuroblast,ganglion mother cell" FBgn0024595 ziplock ziplock http://flybase.net/reports/FBgn0024595.html gene 16-Dec-15 2015_12 FBgn0029989 CG15333 http://flybase.net/reports/FBgn0029989.html FBgn0029988 protein_coding_gene CG18293 IPR006610=Domain of unknown function DM7 CG15333 16-Dec-15 2015_12 viable DRSC18153 K 0.743692422 0.563382824 -0.14482529 0.387112552 0.732416646 2.723764001 FBgn0052181 CG32181 http://flybase.net/reports/FBgn0052181.html FBgn0063316 protein_coding_gene BcDNA:AT19257 CG32181 16-Dec-15 2015_12 viable FBgn0040668 CG17409 http://flybase.net/reports/FBgn0040668.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004770 l(3)89Ei lethal (3) 89Ei http://flybase.net/reports/FBgn0004770.html gene 16-Dec-15 2015_12 lethal FBgn0020248 stet stem cell tumor http://flybase.net/reports/FBgn0020248.html "FBgn0035221, FBgn0035223, FBgn0041725, FBgn0053166" protein_coding_gene "0008236=serine-type peptidase activity, 0005509=calcium ion binding, 0004252=serine-type endopeptidase activity" "0006508=proteolysis, 0007173=epidermal growth factor receptor signaling pathway" "0016021=integral component of membrane, 0005886=plasma membrane" "rho2, Brho, CG33166, brho, Rho2, brother of rhomboid, B-Rho, rho-2, CG12504, CG12083, Stem cell tumor, Rho-2, rhomboid-2" "IPR002610=Peptidase S54, rhomboid, IPR017213=Peptidase S54, rhomboid, metazoan, IPR022764=Peptidase S54, rhomboid domain, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG33166 16-Dec-15 2015_12 ENSDARG00000070311(rhbdl3) WBGene00004400(rom-1) ENSXETG00000005270(rhbdl2) "ENSMUSG00000017692(Rhbdl3),ENSMUSG00000025735(Rhbdl1)" "ENSG00000141314(RHBDL3),ENSG00000103269(RHBDL1)" "viable,female sterile,recessive,fertile,male sterile" "testis,germline clone,germarium,spectrosome | supernumerary,spectrosome | germline clone | supernumerary,male germline stem cell,male germline cell,hub cell,cyst cell,female germline stem cell,egg chamber,ovariole,ovarian sheath cell,wing vein,ectopic,chorion,dorsal appendage,wing" DRSC08283 IE -0.839401677 1.538255786 1.685114917 -0.897983874 -0.044453521 -0.212339295 FBgn0085407 Pvf3 PDGF- and VEGF-related factor 3 http://flybase.net/reports/FBgn0085407.html "FBgn0031890, FBgn0031891, FBgn0051629, FBgn0031889, FBan0031629, FBgn0031892" protein_coding_gene "0008083=growth factor activity, 0005172=vascular endothelial growth factor receptor binding" "0008039=synaptic target recognition, 0007435=salivary gland morphogenesis, 0035099=hemocyte migration, 0048010=vascular endothelial growth factor receptor signaling pathway" 0016020=membrane "CG31629, VEGF27Ca, CG13781, PVFs, PVF, PVF3, Vegf27Ca, Pvf, DmVEGF-3, CG34378, pvf3, CG13782, CG4492, CG13783, VEGF" "IPR000072=PDGF/VEGF domain, IPR029034=Cystine-knot cytokine" CG34378 16-Dec-15 2015_12 " embryonic stage | stage 9-11 , embryonic stage | stage 11-13 , embryonic stage | stage 9-15 " " posterior ectoderm

restricted , Malpighian tubule

, embryonic hindgut

, embryonic foregut

, ventral nerve cord

" """DRSC02284, DRSC02286"" " IK FBgn0014911 anon-4Fe anon-4Fe http://flybase.net/reports/FBgn0014911.html gene 16-Dec-15 2015_12 FBgn0267725 CR46058 http://flybase.net/reports/FBgn0267725.html non_protein_coding_gene CR46058 16-Dec-15 2015_12 FBgn0260113 2L3807 http://flybase.net/reports/FBgn0260113.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0053290 CG33290 http://flybase.net/reports/FBgn0053290.html protein_coding_gene CG33290 16-Dec-15 2015_12 viable FBgn0034441 CG10081 http://flybase.net/reports/FBgn0034441.html protein_coding_gene IPR007484=Peptidase M28 CG10081 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0027148 l(3)71CDb lethal (3) 71CDb http://flybase.net/reports/FBgn0027148.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014358 ms(3)HB665 ms(3)HB665 http://flybase.net/reports/FBgn0014358.html gene 16-Dec-15 2015_12 FBgn0005472 l(1)ts875 lethal (1) ts875 http://flybase.net/reports/FBgn0005472.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0011196 l(1)302-11 lethal (1) 302-11 http://flybase.net/reports/FBgn0011196.html FBgn0010202 gene 302-11 16-Dec-15 2015_12 "lethal,recessive" FBgn0260815 EY10546 http://flybase.net/reports/FBgn0260815.html gene 16-Dec-15 2015_12 FBgn0030793 CG9125 http://flybase.net/reports/FBgn0030793.html FBgn0052566 protein_coding_gene 0008409=5'-3' exonuclease activity 0006402=mRNA catabolic process 0005634=nucleus CG32566 IPR013961=RAI1-like CG9125 16-Dec-15 2015_12 ENSDARG00000036852(zgc:92781) YGL246C(RAI1) WBGene00001050(dom-3) ENSXETG00000027585(DOM3Z) ENSMUSG00000040482(Dom3z) "ENSG00000206266,ENSG00000204348(DOM3Z),ENSG00000206346" FBgn0031142 r-cup ryder cup http://flybase.net/reports/FBgn0031142.html protein_coding_gene 0007140=male meiosis "ryder-cup, CG10998" IPR011990=Tetratricopeptide-like helical domain CG10998 16-Dec-15 2015_12 viable FBgn0004426 LysC Lysozyme C http://flybase.net/reports/FBgn0004426.html FBgn0002575 pseudogene_attribute 0003796=lysozyme activity "0032504=multicellular organism reproduction, 0019730=antimicrobial humoral response" 0005615=extracellular space "CR9111, Lys C, CG9111, lysC" "IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR019799=Glycoside hydrolase, family 22, conserved site, IPR023346=Lysozyme-like domain, IPR001916=Glycoside hydrolase, family 22" CR9111 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) " adult stage , larval stage && adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0265576 CG44403 http://flybase.net/reports/FBgn0265576.html protein_coding_gene CG44403 16-Dec-15 2015_12 FBgn0003195 r(ADH) regulator of ADH http://flybase.net/reports/FBgn0003195.html gene r[26-43] 16-Dec-15 2015_12 FBgn0266433 CG45063 http://flybase.net/reports/FBgn0266433.html protein_coding_gene "0046872=metal ion binding, 0000166=nucleotide binding" CG3701 "IPR004014=Cation-transporting P-type ATPase, N-terminal, IPR008250=P-type ATPase, A domain" CG45063 16-Dec-15 2015_12 FBgn0004933 a(2)48 abnormal abdomen (2) 48 http://flybase.net/reports/FBgn0004933.html gene 16-Dec-15 2015_12 "visible,recessive,viable,good,fertile,maternal effect,wild-type" "tergite,sternite,adult abdomen" FBgn0053271 CG33271 http://flybase.net/reports/FBgn0053271.html "FBgn0036175, FBgn0040819, FBgn0052084" protein_coding_gene "CG14139, CG6100, CG32084" CG33271 16-Dec-15 2015_12 FBgn0031034 CG14205 http://flybase.net/reports/FBgn0031034.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG14205 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" viable FBgn0262358 CG43056 http://flybase.net/reports/FBgn0262358.html protein_coding_gene CG43056 16-Dec-15 2015_12 FBgn0032771 CG17349 http://flybase.net/reports/FBgn0032771.html FBgn0044669 protein_coding_gene anon-WO0140519.204 "IPR019399=Parkin co-regulated protein, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG17349 16-Dec-15 2015_12 WBGene00017122(E04F6.2) ENSXETG00000010781(PACRG) viable FBgn0019765 l(1)56 lethal (1) 56 http://flybase.net/reports/FBgn0019765.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002875 Mu(f3N) Mutator of forked-3N http://flybase.net/reports/FBgn0002875.html gene Mutator forked-3N 16-Dec-15 2015_12 FBgn0035110 thoc7 thoc7 http://flybase.net/reports/FBgn0035110.html protein_coding_gene "0006406=mRNA export from nucleus, 0006397=mRNA processing" "0000347=THO complex, 0000445=THO complex part of transcription export complex, 0005634=nucleus, 0043234=protein complex" "THOC7, CG17143" IPR008501=THO complex subunit 7/Mft1 CG17143 16-Dec-15 2015_12 ENSDARG00000015394(thoc7) WBGene00007195(B0513.2) ENSXETG00000006539(BC062491.1) ENSMUSG00000053453(Thoc7) ENSG00000163634(THOC7) "viable,female fertile" FBgn0266155 CR44861 http://flybase.net/reports/FBgn0266155.html non_protein_coding_gene CR44861 16-Dec-15 2015_12 FBgn0027843 CAH2 Carbonic anhydrase 2 http://flybase.net/reports/FBgn0027843.html FBgn0036261 protein_coding_gene 0004089=carbonate dehydratase activity 0006730=one-carbon metabolic process 0031233=intrinsic component of external side of plasma membrane "CT21171, CG6906" "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class" CG6906 16-Dec-15 2015_12 WBGene00000281(cah-3) viable FBgn0001621 l(1)dh1 lethal (1) discs heterogeneous 1 http://flybase.net/reports/FBgn0001621.html gene l(1)d.het.-1 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" ventral thoracic disc FBgn0016070 smg smaug http://flybase.net/reports/FBgn0016070.html FBgn0010432 protein_coding_gene "0003729=mRNA binding, 0030371=translation repressor activity, 0000900=translation repressor activity, nucleic acid binding, 0003730=mRNA 3'-UTR binding, 0017022=myosin binding" "0017148=negative regulation of translation, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0043488=regulation of mRNA stability, 0051236=establishment of RNA localization" "0005737=cytoplasm, 0000932=cytoplasmic mRNA processing body" "anon-D69, D69, dSmaug, CG5263, unnamed, anonD69, SMG, Smaug, Smg, SMAUG, Smau" "IPR015327=Smaug, pseudo-HEAT analogous topology, IPR013761=Sterile alpha motif/pointed domain, IPR016024=Armadillo-type fold, IPR001660=Sterile alpha motif domain" CG5263 16-Dec-15 2015_12 "ENSXETG00000002903(SAMD4B),ENSXETG00000012217(SAMD4A)" "ENSMUSG00000037513(Samd4b),ENSMUSG00000021838(Samd4)" "ENSG00000020577(SAMD4A),ENSG00000179134(SAMD4B)" "viable,fertile,wild-type,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,neuroanatomy defective" "syncytial blastoderm embryo,maternal effect,cycle 11 embryo,class IV dendritic arborizing neuron,ovary,class IV dendritic arborizing neuron | third instar larval stage" DRSC28033 K 0.573015392 0.231406075 0.31387203 -0.17976781 -2.340000303 0.592201943 FBgn0052190 NUCB1 NUCB1 http://flybase.net/reports/FBgn0052190.html FBgn0023185 protein_coding_gene "0003824=catalytic activity, 0005509=calcium ion binding, 0003677=DNA binding" "0005975=carbohydrate metabolic process, 0032504=multicellular organism reproduction, 0050829=defense response to Gram-negative bacterium" "0005794=Golgi apparatus, 0005615=extracellular space, 0012505=endomembrane system" "nucb1, CG5587, NucB1, CG32190" "IPR011992=EF-hand domain pair, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR018247=EF-Hand 1, calcium-binding site" CG32190 16-Dec-15 2015_12 "ENSDARG00000036299(nucb2a),ENSDARG00000036291(nucb2b),ENSDARG00000054833(nucb1)" WBGene00009674(nucb-1) "ENSXETG00000021229(nucb1),ENSXETG00000016026(NUCB2)" "ENSMUSG00000030659(Nucb2),ENSMUSG00000030824(Nucb1)" "ENSG00000104805(NUCB1),ENSG00000070081(NUCB2)" " embryonic stage | stage >=11 , embryonic stage | early " " embryonic/larval salivary gland

,

ubiquitous " embryonic stage embryonic/larval salivary gland

"viable,fertile" FBgn0264956 CR44125 http://flybase.net/reports/FBgn0264956.html non_protein_coding_gene lincRNA.250 CR44125 16-Dec-15 2015_12 FBgn0065981 iab-5PRE iab-5 Polycomb group response element http://flybase.net/reports/FBgn0065981.html regulatory_region 16-Dec-15 2015_12 FBgn0011956 tRNA:R2:42Ab transfer RNA:arg2:42Ab http://flybase.net/reports/FBgn0011956.html "FBgn0003757, FBgn0011947, FBgn0050314, FBgn0060089" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033429=CGU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[arg], CR30314, chr2R.trna8-ArgACG, tRNA:R:ACG:AE002769-d, AE002769.trna16-ArgACG, tRNA[Arg][[2]], tRNA Arg, tRNA:arg2:42Ab, tRNA:R1, transfer RNA:arg1, tRNA[Arg], tRNA:arg1" CR30314 16-Dec-15 2015_12 FBgn0262784 roX1::Dpse\roX1 http://flybase.net/reports/FBgn0262784.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0062615 Mod(var)1259 Mod(var)1259 http://flybase.net/reports/FBgn0062615.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1259 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0069148 mcl(3)Z3808 mcl(3)Z3808 http://flybase.net/reports/FBgn0069148.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0003245 r(ë±GPDH) regulator of ë± GPDH http://flybase.net/reports/FBgn0003245.html gene "m(GPDH), r[3-55.4], m[alpha-GPDH], regulator of alpha glycerol phosphate dehydrogenase" 16-Dec-15 2015_12 FBgn0033702 CG8854 http://flybase.net/reports/FBgn0033702.html protein_coding_gene CG8854 16-Dec-15 2015_12 viable FBgn0029051 l(1)G0458 lethal (1) G0458 http://flybase.net/reports/FBgn0029051.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0005488 l(1)ts1901 lethal (1) ts1901 http://flybase.net/reports/FBgn0005488.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0014264 l(2)k04301a lethal (2) k04301a http://flybase.net/reports/FBgn0014264.html gene 0007446=imaginal disc growth "l(2)43/1, l(2)k04301, l(2)k00202" 16-Dec-15 2015_12 "lethal,recessive,hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval brain,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc" FBgn0261274 Ero1L Endoplasmic reticulum oxidoreductin-1-like http://flybase.net/reports/FBgn0261274.html "FBgn0028736, FBgn0014288" protein_coding_gene "0016671=oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, 0016491=oxidoreductase activity, 0003756=protein disulfide isomerase activity" "0055114=oxidation-reduction process, 0051085=chaperone mediated protein folding requiring cofactor" 0005783=endoplasmic reticulum "l(3)SH22, kiga, l(3)64Ag, CG1333, ERO1-L, lethal (3) 64Ag, Ero1l, Endoplasmic reticulum oxidoreductin-1L, Ero1L" IPR007266=Endoplasmic reticulum oxidoreductin 1 CG1333 16-Dec-15 2015_12 "ENSDARG00000030004,ENSDARG00000015228(ero1l)" YML130C(ERO1) WBGene00001334(ero-1) "ENSXETG00000012205(ERO1L),ENSXETG00000016223(ERO1LB)" "ENSMUSG00000021831(Ero1l),ENSMUSG00000057069(Ero1lb)" "ENSG00000197930(ERO1L),ENSG00000086619(ERO1LB)" FBgn0033894 CG13352 http://flybase.net/reports/FBgn0033894.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035585 ATPsynCF6L "ATP synthase, coupling factor 6-like" http://flybase.net/reports/FBgn0035585.html protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" 0015986=ATP synthesis coupled proton transport "0005753=mitochondrial proton-transporting ATP synthase complex, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATP synthase Coupling factor 6, ATP synthase coupling factor 6, ATPR, CG12027" "IPR008387=ATPase, F0 complex, subunit F6, mitochondrial" CG12027 16-Dec-15 2015_12 DRSC08232 I 1.950521044 0.614457678 0.223087393 0.220130787 0.276438355 -0.33536531 FBgn0051803 CG31803 http://flybase.net/reports/FBgn0051803.html FBgn0063701 protein_coding_gene BcDNA:AT29119 CG31803 16-Dec-15 2015_12 ENSDARG00000017355(rsph9) ENSXETG00000010879(TNeu080g17.1) ENSMUSG00000023966(Rsph9) ENSG00000172426(RSPH9) partially lethal - majority die FBgn0263523 mir-4972 mir-4972 stem loop http://flybase.net/reports/FBgn0263523.html miRNA_gene "CR43508, dme-mir-4972" CR43508 16-Dec-15 2015_12 FBgn0266989 CR45440 http://flybase.net/reports/FBgn0266989.html non_protein_coding_gene CR45440 16-Dec-15 2015_12 FBgn0265076 CR44187 http://flybase.net/reports/FBgn0265076.html non_protein_coding_gene CR44187 16-Dec-15 2015_12 FBgn0052167 CG32167 http://flybase.net/reports/FBgn0052167.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0040133 l(2)22Af lethal (2) 22Af http://flybase.net/reports/FBgn0040133.html gene T 16-Dec-15 2015_12 "lethal,recessive" FBgn0005405 l(1)10Ch lethal (1) 10Ch http://flybase.net/reports/FBgn0005405.html gene l(1)JC35 16-Dec-15 2015_12 lethal FBgn0036498 CG13455 http://flybase.net/reports/FBgn0036498.html protein_coding_gene CG13455 16-Dec-15 2015_12 "viable,fertile" FBgn0026876 CG11403 http://flybase.net/reports/FBgn0026876.html protein_coding_gene "0004386=helicase activity, 0003677=DNA binding, 0005524=ATP binding, 0004003=ATP-dependent DNA helicase activity" 0006289=nucleotide-excision repair "EG:33C11.2, cg11403" "IPR014013=Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR013020=DNA helicase (DNA repair), Rad3 type, IPR010614=DEAD2, IPR006555=ATP-dependent helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG11403 16-Dec-15 2015_12 ENSDARG00000011072(zgc:92172) YPL008W(CHL1) WBGene00010839(M03C11.2) ENSMUSG00000035842(Ddx11) "ENSG00000013573(DDX11),ENSG00000111788,ENSG00000214826" "viable,fertile" FBgn0027183 l(2)60A-K lethal (2) 60A-K http://flybase.net/reports/FBgn0027183.html gene 16-Dec-15 2015_12 lethal FBgn0010014 CanB Calcineurin B http://flybase.net/reports/FBgn0010014.html "FBgn0004466, FBgn0029757, FBgn0047037" protein_coding_gene "0005509=calcium ion binding, 0008597=calcium-dependent protein serine/threonine phosphatase regulator activity, 0005516=calmodulin binding" "0051533=positive regulation of NFAT protein import into nucleus, 0016192=vesicle-mediated transport, 0006470=protein dephosphorylation, 0007269=neurotransmitter secretion, 0030431=sleep" "0008021=synaptic vesicle, 0005955=calcineurin complex" "CG4209, Calcineurin B, Can, CnB, dCnB1, canB-4F, CNB, BcDNA:RH11383" "IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG4209 16-Dec-15 2015_12 "ENSDARG00000069360,ENSDARG00000013013(ppp3r1a)" YKL190W(CNB1) WBGene00000554(cnb-1) ENSXETG00000017355(ppp3r1) ENSMUSG00000033953(Ppp3r1) ENSG00000115953 embryonic stage "viable,fertile,wild-type,sleep defective,locomotor behavior defective" FBgn0267992 CR46259 http://flybase.net/reports/FBgn0267992.html non_protein_coding_gene CR46259 16-Dec-15 2015_12 FBgn0038448 CG12783 http://flybase.net/reports/FBgn0038448.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG12783 16-Dec-15 2015_12 "viable,fertile" FBgn0024871 l(2)k09033 lethal (2) k09033 http://flybase.net/reports/FBgn0024871.html gene unnamed 16-Dec-15 2015_12 lethal FBgn0024722 Su(var)57D58D Su(var)57D58D http://flybase.net/reports/FBgn0024722.html gene unnamed 16-Dec-15 2015_12 FBgn0267971 Ir52e Ionotropic receptor 52e http://flybase.net/reports/FBgn0267971.html protein_coding_gene IR52e 16-Dec-15 2015_12 FBgn0033609 Fbl6 F-box and leucine-rich repeat protein 6 http://flybase.net/reports/FBgn0033609.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0032093=SAM domain binding" "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 2000060=positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0031647=regulation of protein stability" "0005654=nucleoplasm, 0019005=SCF ubiquitin ligase complex" "FBXL6, Fbl6, CG13213, fbl6" "IPR001810=F-box domain, IPR001611=Leucine-rich repeat" CG13213 16-Dec-15 2015_12 ENSMUSG00000022559(Fbxl6) ENSG00000182325(FBXL6) "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "trichogen cell,mesothoracic tergum" DRSC06335 I -1.556861459 0.621255344 0.942042203 0.1390746 -0.582396972 0.65945824 FBgn0061161 l(1)7Bg lethal (1) 7Bg http://flybase.net/reports/FBgn0061161.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020318 anon-86Fa anon-86Fa http://flybase.net/reports/FBgn0020318.html gene "1D10, unnamed" 16-Dec-15 2015_12 FBgn0000029 AcpB Accessory gland protein B http://flybase.net/reports/FBgn0000029.html gene 16-Dec-15 2015_12 FBgn0000945 fs(2)A15 female sterile (2) A15 http://flybase.net/reports/FBgn0000945.html gene 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oocyte" FBgn0040353 CG14417 http://flybase.net/reports/FBgn0040353.html FBgn0029637 protein_coding_gene EG:BACR43E12.6 CG14417 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000767 fs(1)A1024 female sterile (1) A1024 http://flybase.net/reports/FBgn0000767.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of pupal stage,rescuable maternal effect,some die during pupal stage" wing FBgn0039386 CG5948 http://flybase.net/reports/FBgn0039386.html protein_coding_gene "0005507=copper ion binding, 0008270=zinc ion binding, 0004784=superoxide dismutase activity" "0055114=oxidation-reduction process, 0019430=removal of superoxide radicals" "0005739=mitochondrion, 0005829=cytosol, 0005634=nucleus" "IPR001424=Superoxide dismutase, copper/zinc binding domain" CG5948 16-Dec-15 2015_12 FBgn0051955 CG31955 http://flybase.net/reports/FBgn0051955.html FBgn0031565 protein_coding_gene CG31955 16-Dec-15 2015_12 viable FBgn0025931 hip57 hb-interacting protein 57 http://flybase.net/reports/FBgn0025931.html gene 16-Dec-15 2015_12 FBgn0266873 CR45334 http://flybase.net/reports/FBgn0266873.html non_protein_coding_gene CR45334 16-Dec-15 2015_12 FBgn0260808 EP3-1199 http://flybase.net/reports/FBgn0260808.html gene 16-Dec-15 2015_12 FBgn0264375 CR43827 http://flybase.net/reports/FBgn0264375.html non_protein_coding_gene CR43827 16-Dec-15 2015_12 FBgn0037128 CG14572 http://flybase.net/reports/FBgn0037128.html protein_coding_gene CG14572 16-Dec-15 2015_12 viable FBgn0265785 CG44574 http://flybase.net/reports/FBgn0265785.html protein_coding_gene CG44574 16-Dec-15 2015_12 FBgn0035069 CG3611 http://flybase.net/reports/FBgn0035069.html FBgn0063339 protein_coding_gene BcDNA:AT12780 CG3611 16-Dec-15 2015_12 viable FBgn0053181 CG33181 http://flybase.net/reports/FBgn0053181.html "FBgn0030046, FBan0033181, FBgn0047087, FBgn0052714" protein_coding_gene 0008324=cation transmembrane transporter activity 0006812=cation transport "CG32714, CG1521" "IPR006667=SLC41 divalent cation transporters, integral membrane domain" CG33181 16-Dec-15 2015_12 "ENSDARG00000070214(slc41a1),ENSDARG00000061272(LOC564564)" WBGene00019504(K07H8.2) "ENSXETG00000004787(SLC41A3),ENSXETG00000001883(slc41a2)" "ENSMUSG00000034591(Slc41a2),ENSMUSG00000013275(Slc41a1),ENSMUSG00000030089(Slc41a3)" "ENSG00000136052(SLC41A2),ENSG00000133065(SLC41A1)" viable FBgn0266732 CR45205 http://flybase.net/reports/FBgn0266732.html non_protein_coding_gene CR45205 16-Dec-15 2015_12 FBgn0031518 CG3277 http://flybase.net/reports/FBgn0031518.html protein_coding_gene "0005524=ATP binding, 0004713=protein tyrosine kinase activity" 0006468=protein phosphorylation "IPR000719=Protein kinase domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR008266=Tyrosine-protein kinase, active site" CG3277 16-Dec-15 2015_12 viable FBgn0015025 CkIIë±-i1 CKII-ë± subunit interactor-1 http://flybase.net/reports/FBgn0015025.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0019901=protein kinase binding, 0046872=metal ion binding" "0006351=transcription, DNA-templated" 0005634=nucleus "ZFP47, CkIIalpha-i1, CG6215, CKIIalpha-iI, dCKIIalpha-i1, DmA35, CKIIalpha-I1" "IPR007087=Zinc finger, C2H2, IPR027775=C2H2- zinc finger protein family, IPR015880=Zinc finger, C2H2-like" CG6215 16-Dec-15 2015_12 viable FBgn0264474 CR43882 http://flybase.net/reports/FBgn0264474.html non_protein_coding_gene CR43882 16-Dec-15 2015_12 FBgn0259699 CG42353 http://flybase.net/reports/FBgn0259699.html "FBan0009216, FBgn0030726" protein_coding_gene CG9216 CG42353 16-Dec-15 2015_12 "viable,fertile" FBgn0031549 Spindly Spindly http://flybase.net/reports/FBgn0031549.html protein_coding_gene 0008157=protein phosphatase 1 binding 0030071=regulation of mitotic metaphase/anaphase transition "0000776=kinetochore, 0005874=microtubule" CG15415 CG15415 16-Dec-15 2015_12 DRSC00430 IE -0.053291631 -2.131649703 1.474836741 -4.287608382 -0.04942602 -0.959051599 FBgn0015931 dsRNABP5 ds-RNA binding protein 5 http://flybase.net/reports/FBgn0015931.html gene 0003725=double-stranded RNA binding dsRNABP#5 16-Dec-15 2015_12 FBgn0262575 CG43115 http://flybase.net/reports/FBgn0262575.html protein_coding_gene CG43115 16-Dec-15 2015_12 FBgn0022090 l(2)k07312b lethal (2) k07312b http://flybase.net/reports/FBgn0022090.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266435 CG45065 http://flybase.net/reports/FBgn0266435.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors, 0016491=oxidoreductase activity, 0050660=flavin adenine dinucleotide binding" "0055114=oxidation-reduction process, 0045455=ecdysteroid metabolic process" "CG9517, Dm GMCepsilon1" "IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal" CG45065 16-Dec-15 2015_12 viable FBgn0062708 EP1020 EP1020 http://flybase.net/reports/FBgn0062708.html gene EP(2)1020 16-Dec-15 2015_12 FBgn0031564 CG2816 http://flybase.net/reports/FBgn0031564.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG2816 16-Dec-15 2015_12 ENSMUSG00000074593(Gm14316) ENSG00000168630 viable FBgn0069242 eca eclair http://flybase.net/reports/FBgn0069242.html "FBgn0037732, FBgn0053104" protein_coding_gene 0005215=transporter activity "0048042=regulation of post-mating oviposition, 0035220=wing disc development, 0006888=ER to Golgi vesicle-mediated transport, 0002121=inter-male aggressive behavior, 0070863=positive regulation of protein exit from endoplasmic reticulum, 0009953=dorsal/ventral pattern formation, 0007030=Golgi organization, 0090263=positive regulation of canonical Wnt signaling pathway, 0048193=Golgi vesicle transport, 0061357=positive regulation of Wnt protein secretion, 0034389=lipid particle organization, 0000003=reproduction" "0012505=endomembrane system, 0016021=integral component of membrane, 0005794=Golgi apparatus" "CG33104, ECA, p24, Eclair, CG9443" "IPR009038=GOLD domain, IPR015720=TMP21-related" CG33104 16-Dec-15 2015_12 "ENSDARG00000024954(tmed4),ENSDARG00000004261(tmed9)" "YGL002W(ERP6),YAR002C-A(ERP1),YHR110W(ERP5)" WBGene00013360(Y60A3A.9) "ENSXETG00000018999(tmed4),ENSXETG00000006739(tmed9)" ENSMUSG00000004394(Tmed4) "ENSG00000158604(TMED4),ENSG00000184840(TMED9)" "behavior defective,recessive,viable,fertile,lethal,maternal effect,female sterile,male semi-sterile,germline clone,partially lethal - majority die,non-rescuable maternal effect,female semi-sterile" "embryonic/first instar larval cuticle,dorsal,germline clone,wing vein,ectopic,wing margin,somatic clone" FBgn0000501 dsp dispersed http://flybase.net/reports/FBgn0000501.html gene "0007443=Malpighian tubule morphogenesis, 0001700=embryonic development via the syncytial blastoderm" Dsp 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" Malpighian tubule FBgn0259611 B0613 http://flybase.net/reports/FBgn0259611.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing vein L3,wing" FBgn0036599 CG13044 http://flybase.net/reports/FBgn0036599.html protein_coding_gene IPR007614=Retinin-like protein CG13044 16-Dec-15 2015_12 viable FBgn0011235 cuc cuckold http://flybase.net/reports/FBgn0011235.html "FBgn0010534, FBgn0011243" gene "0007618=mating, 0008049=male courtship behavior" "male sterile(2) 27CD, ms(2)27CD, ms(2)05158, l(2)03264, l(2)10607, ms(2)06491" 16-Dec-15 2015_12 "lethal,recessive,male sterile,behavior defective,partially lethal - majority die" FBgn0024191 sip1 septin interacting protein 1 http://flybase.net/reports/FBgn0024191.html FBgn0027543 protein_coding_gene "0005515=protein binding, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0005578=proteinaceous extracellular matrix, 0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "CG7238, GH11690, BcDNA:GH11690" "IPR022783=GC-rich sequence DNA-binding factor domain, IPR024933=Septin and tuftelin interacting protein, IPR000467=G-patch domain, IPR022159=Tuftelin interacting protein, N-terminal domain" CG7238 16-Dec-15 2015_12 "ENSDARG00000070977,ENSDARG00000056932(tfip11)" YLR424W(SPP382) WBGene00007412(stip-1) ENSXETG00000003784(TFIP11) ENSMUSG00000029345(Tfip11) ENSG00000100109(TFIP11) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0085557 CG41026 http://flybase.net/reports/FBgn0085557.html FBan0041026 protein_coding_gene 16-Dec-15 2015_12 FBgn0067654 sd-14 sd-14 http://flybase.net/reports/FBgn0067654.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 14 16-Dec-15 2015_12 "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0025561 anon-36Ab anon-36Ab http://flybase.net/reports/FBgn0025561.html gene cDNA II 16-Dec-15 2015_12 FBgn0260242 ssar single-strand annealing reducer http://flybase.net/reports/FBgn0260242.html gene 0045002=double-strand break repair via single-strand annealing 16-Dec-15 2015_12 FBgn0065346 l(2)SH1816 lethal (2) SH1816 http://flybase.net/reports/FBgn0065346.html gene l(2)SH2 1816 16-Dec-15 2015_12 "lethal,recessive" FBgn0265805 CR44594 http://flybase.net/reports/FBgn0265805.html non_protein_coding_gene CR44594 16-Dec-15 2015_12 FBgn0065455 l(2)SH1391 lethal (2) SH1391 http://flybase.net/reports/FBgn0065455.html gene l(2)SH2 1391 16-Dec-15 2015_12 "lethal,recessive" FBgn0085722 CG41615 http://flybase.net/reports/FBgn0085722.html FBan0041615 protein_coding_gene 16-Dec-15 2015_12 FBgn0017622 Eig83B Eig83B http://flybase.net/reports/FBgn0017622.html gene "Ecdysone-induced gene 83B, Eig83" 16-Dec-15 2015_12 FBgn0060502 l(3)S105611 lethal (3) S105611 http://flybase.net/reports/FBgn0060502.html gene 1056/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0051948 CG31948 http://flybase.net/reports/FBgn0051948.html FBgn0031427 protein_coding_gene CG9966 "IPR000626=Ubiquitin domain, IPR029071=Ubiquitin-related domain" CG31948 16-Dec-15 2015_12 viable FBgn0037184 CG14450 http://flybase.net/reports/FBgn0037184.html protein_coding_gene CG14450 16-Dec-15 2015_12 ENSDARG00000059469(zgc:153083) ENSXETG00000020052(C17orf42) ENSMUSG00000046909(1110002N22Rik) ENSG00000172171(C17orf42) FBgn0069407 JJF230 JJF230 http://flybase.net/reports/FBgn0069407.html gene 16-Dec-15 2015_12 stress response defective FBgn0044474 EP1493 EP1493 http://flybase.net/reports/FBgn0044474.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0261256 wiser wings scalloped-eyes rough http://flybase.net/reports/FBgn0261256.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,short lived,female sterile,locomotor behavior defective,visible" "wing,metathoracic tarsal segment,adult abdomen,metathoracic leg,ovary,eye" FBgn0052709 CG32709 http://flybase.net/reports/FBgn0052709.html FBgn0062472 protein_coding_gene BcDNA:HL05735 16-Dec-15 2015_12 FBgn0039527 CG5639 http://flybase.net/reports/FBgn0039527.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005576=extracellular region "N-like, CT17816" "IPR006150=Cysteine-rich repeat, IPR003645=Follistatin-like, N-terminal, IPR011061=Hirudin/antistatin, IPR028150=Lustrin, cysteine-rich repeated domain, IPR000716=Thyroglobulin type-1, IPR004094=Antistasin-like domain, IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR008197=WAP-type 'four-disulfide core' domain" CG5639 16-Dec-15 2015_12 WBGene00015620(C08G9.2) lethal FBgn0263241 Mocs1 Molybdenum cofactor synthesis 1 ortholog http://flybase.net/reports/FBgn0263241.html "FBgn0063910, FBgn0063911, FBgn0063912, FBgn0036122, FBgn0002572" protein_coding_gene "0003824=catalytic activity, 0046872=metal ion binding, 0051539=4 iron, 4 sulfur cluster binding" 0006777=Mo-molybdopterin cofactor biosynthetic process 0019008=molybdopterin synthase complex "mocsI, MOCSI, lxd, Mocs1A, Mocs1, Mocs1B, Mosc1A+Mosc1B, MOCS1B, CG33048, low xanthine dehydrogenase, MOCS1A, MocsI, Mocs1A-B, CG7858" "IPR010505=Molybdenum cofactor synthesis C-terminal, IPR000385=MoaA/nifB/pqqE, iron-sulphur binding, conserved site, IPR013483=Molybdenum cofactor biosynthesis protein A, IPR023046=Molybdenum cofactor biosynthesis C, bacterial-type, IPR006638=Elongator protein 3/MiaB/NifB, IPR007197=Radical SAM, IPR002820=Molybdopterin cofactor biosynthesis C (MoaC) domain, IPR013785=Aldolase-type TIM barrel, IPR023045=Molybdenum cofactor biosynthesis C" CG33048 16-Dec-15 2015_12 "WBGene00009885(F49E2.1),WBGene00009908(F49H6.5)" ENSXETG00000007824() ENSMUSG00000064120 ENSG00000124615(MOCS1) FBgn0062533 ff3 ff3 http://flybase.net/reports/FBgn0062533.html gene 16-Dec-15 2015_12 "mitotic cell cycle defective,meiotic cell cycle defective,male" "mitotic cell cycle,mitotic anaphase,mitotic telophase,cell cycle,nuclear chromosome" FBgn0000003 7SLRNA:CR32864 Signal recognition particle 7SL RNA CR32864 http://flybase.net/reports/FBgn0000003.html non_protein_coding_gene 0006614=SRP-dependent cotranslational protein targeting to membrane "0005786=signal recognition particle, endoplasmic reticulum targeting" "CR32864, 7SLRNA, RNA 7SL, 7SL RNA" CR32864 16-Dec-15 2015_12 FBgn0045865 blood\ORF1 ORF1 http://flybase.net/reports/FBgn0045865.html transposable_element_gene 16-Dec-15 2015_12 FBgn0013244 E(var)261 E(var)261 http://flybase.net/reports/FBgn0013244.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0010188 tu-36e tu-36e http://flybase.net/reports/FBgn0010188.html gene 16-Dec-15 2015_12 FBgn0030896 CG12612 http://flybase.net/reports/FBgn0030896.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085333 CG34304 http://flybase.net/reports/FBgn0085333.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262611 CG43137 http://flybase.net/reports/FBgn0262611.html protein_coding_gene lincRNA.952 CG43137 16-Dec-15 2015_12 FBgn0069056 CG33226 http://flybase.net/reports/FBgn0069056.html "FBgn0053226, FBgn0050283, FBgn0034635" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH37, CG10450, SP37" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG33226 16-Dec-15 2015_12 FBgn0062691 EP1350 EP1350 http://flybase.net/reports/FBgn0062691.html gene EP(X)1350 16-Dec-15 2015_12 visible eye FBgn0260452 CG13984 http://flybase.net/reports/FBgn0260452.html FBgn0031796 protein_coding_gene CG13984 16-Dec-15 2015_12 viable FBgn0062689 EP1388 EP1388 http://flybase.net/reports/FBgn0062689.html gene EP(X)1388 16-Dec-15 2015_12 spermatogonium FBgn0262543 CR43097 http://flybase.net/reports/FBgn0262543.html non_protein_coding_gene CG43097 CR43097 16-Dec-15 2015_12 FBgn0014865 Mtk Metchnikowin http://flybase.net/reports/FBgn0014865.html FBgn0061385 protein_coding_gene "0019732=antifungal humoral response, 0006952=defense response, 0009617=response to bacterium, 0050829=defense response to Gram-negative bacterium, 0050830=defense response to Gram-positive bacterium, 0050832=defense response to fungus, 0019731=antibacterial humoral response" 0005576=extracellular region "BcDNA:RH07954, metchnikovin, Metc, CG8175, metk, Metch, metch, Metchnikowin B, metchnikowin-2, metchinkowin, metchnikowin, mtk, metchikowin, metchnikowin-1, Metchnikowin A, METCH, Metchnikowin precursor, Drosophila Immune induced molecule 17, Metchnikowine, DIM 17" IPR012513=Metchnikowin CG8175 16-Dec-15 2015_12 embryonic stage | 6-24 hr viable FBgn0038706 CG3517 http://flybase.net/reports/FBgn0038706.html protein_coding_gene CG3517 16-Dec-15 2015_12 "visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005197 l(3)36d24 lethal (3) 36d24 http://flybase.net/reports/FBgn0005197.html gene 16-Dec-15 2015_12 lethal FBgn0261574 kug kugelei http://flybase.net/reports/FBgn0261574.html "FBgn0036930, FBgn0001329" protein_coding_gene "0004872=receptor activity, 0005509=calcium ion binding, 0050839=cell adhesion molecule binding" "0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0044331=cell-cell adhesion mediated by cadherin, 0030950=establishment or maintenance of actin cytoskeleton polarity, 0007431=salivary gland development, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0007442=hindgut morphogenesis, 0050829=defense response to Gram-negative bacterium, 0045571=negative regulation of imaginal disc growth, 0007440=foregut morphogenesis, 0048477=oogenesis, 0042247=establishment of planar polarity of follicular epithelium, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0045089=positive regulation of innate immune response, 0007424=open tracheal system development" "0005887=integral component of plasma membrane, 0009925=basal plasma membrane, 0005925=focal adhesion" "fat-like, Cad76E, kugel, CG7749, CT23445, DCad76E, fat2, Ftl, RE-A, ftl" "IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR001881=EGF-like calcium-binding domain, IPR002126=Cadherin, IPR015919=Cadherin-like, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR020894=Cadherin conserved site" CG7749 16-Dec-15 2015_12 "ENSDARG00000017591(fat1),ENSDARG00000019063(LOC565591),ENSDARG00000033840,ENSDARG00000018923(LOC568468),ENSDARG00000062246" WBGene00000396(cdh-4) "ENSXETG00000017135(FAT1),ENSXETG00000017133(FAT3)" "ENSMUSG00000070047(Fat1),ENSMUSG00000074505(Fat3),ENSMUSG00000055333(Fat2)" "ENSG00000083857(FAT1),ENSG00000165323(FAT3),ENSG00000086570(FAT2)" FBgn0265790 CR44579 http://flybase.net/reports/FBgn0265790.html non_protein_coding_gene CR44579 16-Dec-15 2015_12 FBgn0051513 CG31513 http://flybase.net/reports/FBgn0051513.html protein_coding_gene 16-Dec-15 2015_12 DRSC23522 K -0.00125279 -0.285870801 -0.528721533 0.850536889 1.842946422 -0.650106921 FBgn0060948 l(3)S037901 lethal (3) S037901 http://flybase.net/reports/FBgn0060948.html gene 0379/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0036198 crim crimpled http://flybase.net/reports/FBgn0036198.html protein_coding_gene "0019991=septate junction assembly, 0035151=regulation of tube size, open tracheal system, 0035002=liquid clearance, open tracheal system" 0005918=septate junction "crim, crimpled, CG6038, Crim" CG6038 16-Dec-15 2015_12 "viable,visible" "embryonic/larval dorsal trunk,trichogen cell" FBgn0001770 l(1)M41 lethal (1) M41 http://flybase.net/reports/FBgn0001770.html gene 16-Dec-15 2015_12 lethal FBgn0260605 2L1561 http://flybase.net/reports/FBgn0260605.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0024361 Tsp2A Tetraspanin 2A http://flybase.net/reports/FBgn0024361.html protein_coding_gene 0016021=integral component of membrane "CG11415, EG:8D8.7, Dm.Tsp2A, D8.7" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG11415 16-Dec-15 2015_12 FBgn0263457 CR43480 http://flybase.net/reports/FBgn0263457.html non_protein_coding_gene CR43480 16-Dec-15 2015_12 FBgn0030060 CG2004 http://flybase.net/reports/FBgn0030060.html protein_coding_gene "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG2004 16-Dec-15 2015_12 "WBGene00007810(C29F7.1),WBGene00007811(C29F7.2),WBGene00014192(nhr-246)" viable FBgn0266781 CR45246 http://flybase.net/reports/FBgn0266781.html non_protein_coding_gene CR45246 16-Dec-15 2015_12 FBgn0262017 CG42830 http://flybase.net/reports/FBgn0262017.html "FBgn0032655, FBgn0262012, FBgn0046862" protein_coding_gene "anon-AE003656.1, CG7527" IPR024132=Akirin CG42830 16-Dec-15 2015_12 FBgn0028013 l(3)S108310a lethal (3) S108310a http://flybase.net/reports/FBgn0028013.html gene "1083/10, l(3)S108310" 16-Dec-15 2015_12 "lethal,recessive" FBgn0022216 l(2)k03610 lethal (2) k03610 http://flybase.net/reports/FBgn0022216.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016897 l(3)64Cg lethal (3) 64Cg http://flybase.net/reports/FBgn0016897.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036138 CG14143 http://flybase.net/reports/FBgn0036138.html protein_coding_gene chr3L_11128040_11128584.0 CG14143 16-Dec-15 2015_12 FBgn0065513 l(2)SH1164 lethal (2) SH1164 http://flybase.net/reports/FBgn0065513.html gene l(2)SH2 1164 16-Dec-15 2015_12 "lethal,recessive" FBgn0004133 blow blown fuse http://flybase.net/reports/FBgn0004133.html protein_coding_gene 0005515=protein binding "0007519=skeletal muscle tissue development, 0007520=myoblast fusion, 0030036=actin cytoskeleton organization, 0007498=mesoderm development" "0002102=podosome, 0005737=cytoplasm" "CG1363, l(2)43Eb, blownfuse, blown-fuse, Blow, Blown fuse" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG1363 16-Dec-15 2015_12 " embryonic stage | stage 11-14 , embryonic stage | stage 10 " " embryonic myoblast

, mesoderm | restricted & segmentally repeated

" embryonic stage | stage 11-14 embryonic myoblast

"lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,viable" "embryonic myoblast,A1-7 dorsal acute muscle 1,myoblast,somatic muscle primordium,embryonic/larval somatic muscle,presumptive embryonic/larval muscle system,fusion competent cell" FBgn0001611 l(1)dd3 lethal (1) discs degenerate 3 http://flybase.net/reports/FBgn0001611.html gene "l(1)d deg-3, l(1)d.deg.-3, l(1)d.deg.3, d.deg.-3" 16-Dec-15 2015_12 "mitotic cell cycle defective,cell lethal,germline clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "cell cycle,imaginal disc,cell autonomous,somatic clone,embryonic/larval brain,embryonic/larval optic lobe,foregut imaginal ring,embryonic/larval salivary gland,gonad,male" FBgn0260016 bha bahia http://flybase.net/reports/FBgn0260016.html gene 16-Dec-15 2015_12 viable "chorion,dorsal appendage,chorion | germline clone" FBgn0262888 CR43243 http://flybase.net/reports/FBgn0262888.html non_protein_coding_gene CG43243 CR43243 16-Dec-15 2015_12 FBgn0063382 snoRNA:U29:54Ed snoRNA:U29:54Ed http://flybase.net/reports/FBgn0063382.html snoRNA_gene "U29snoRNA, CR32895, DmSnR71b" CR32895 16-Dec-15 2015_12 FBgn0016784 anon-91Ab anon-91Ab http://flybase.net/reports/FBgn0016784.html gene 16-Dec-15 2015_12 FBgn0031023 CG14200 http://flybase.net/reports/FBgn0031023.html protein_coding_gene "IPR015880=Zinc finger, C2H2-like, IPR000313=PWWP domain" CG14200 16-Dec-15 2015_12 FBgn0262185 mir-995 mir-995 stem loop http://flybase.net/reports/FBgn0262185.html miRNA_gene "miR-995, 995, CR42892, miR-20072" CR42892 16-Dec-15 2015_12 "visible,lethal" "eye,male,wing,wing margin,1st posterior cell" FBgn0002062 l(2)40Fg lethal (2) 40Fg http://flybase.net/reports/FBgn0002062.html gene "GroupVI, l(2L)D', 40Fg, l(2Lh)Fg" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0262363 CG43061 http://flybase.net/reports/FBgn0262363.html protein_coding_gene 0009405=pathogenesis 0005576=extracellular region IPR012624=Conotoxin I-superfamily CG43061 16-Dec-15 2015_12 FBgn0037051 CG10565 http://flybase.net/reports/FBgn0037051.html protein_coding_gene "0051082=unfolded protein binding, 0003677=DNA binding" 0006457=protein folding "IPR001623=DnaJ domain, IPR017877=Myb-like domain, IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like" CG10565 16-Dec-15 2015_12 ENSDARG00000070477(dnajc2) YGR285C(ZUO1) WBGene00001029(dnj-11) ENSXETG00000023108(dnajc2) ENSMUSG00000029014(Dnajc2) ENSG00000105821(DNAJC2) "viable,visible" trichogen cell DRSC11620 I 0.590226745 -2.394098507 0.608748108 0.037200972 -0.255469366 -0.102439536 FBgn0263838 CR43700 http://flybase.net/reports/FBgn0263838.html non_protein_coding_gene CR43700 16-Dec-15 2015_12 FBgn0038315 CG14866 http://flybase.net/reports/FBgn0038315.html protein_coding_gene 0030246=carbohydrate binding "IPR016186=C-type lectin-like, IPR016187=C-type lectin fold, IPR001304=C-type lectin" CG14866 16-Dec-15 2015_12 viable FBgn0030995 CG7914 http://flybase.net/reports/FBgn0030995.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process "IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR008333=Oxidoreductase, FAD-binding domain, IPR001834=NADH:cytochrome b5 reductase (CBR), IPR017938=Riboflavin synthase-like beta-barrel" CG7914 16-Dec-15 2015_12 ENSG00000215883(CYB5RL) viable FBgn0033558 CG12344 http://flybase.net/reports/FBgn0033558.html protein_coding_gene 0016934=extracellular-glycine-gated chloride channel activity 0006811=ion transport 0016935=glycine-gated chloride channel complex "glycine receptor alpha2-like, CT23391" "IPR006201=Neurotransmitter-gated ion-channel, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG12344 16-Dec-15 2015_12 "viable,fertile" FBgn0036410 CG8100 http://flybase.net/reports/FBgn0036410.html protein_coding_gene "0005576=extracellular region, 0005616=larval serum protein complex" lincRNA.S5087 "IPR005203=Hemocyanin, C-terminal, IPR013788=Hemocyanin/hexamerin, IPR008922=Uncharacterised domain, di-copper centre, IPR014756=Immunoglobulin E-set, IPR005204=Hemocyanin, N-terminal" CG8100 16-Dec-15 2015_12 viable FBgn0035641 CG5568 http://flybase.net/reports/FBgn0035641.html protein_coding_gene 0016207=4-coumarate-CoA ligase activity 0008152=metabolic process "IPR000873=AMP-dependent synthetase/ligase, IPR025110=AMP-binding enzyme C-terminal domain" CG5568 16-Dec-15 2015_12 lethal FBgn0260246 GSd210 http://flybase.net/reports/FBgn0260246.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0028132 l(3)S051022a lethal (3) S051022a http://flybase.net/reports/FBgn0028132.html gene "l(3)S051022, 0510/22" 16-Dec-15 2015_12 "lethal,recessive" FBgn0000396 cv-b crossveinless b http://flybase.net/reports/FBgn0000396.html gene 16-Dec-15 2015_12 "visible,recessive" "anterior crossvein,posterior crossvein" FBgn0035558 CG11357 http://flybase.net/reports/FBgn0035558.html FBgn0047279 protein_coding_gene "0016757=transferase activity, transferring glycosyl groups, 0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" 0006486=protein glycosylation 0016020=membrane "BcDNA:GM04393, dbeta3GnT, GalT2" "IPR002659=Glycosyl transferase, family 31" CG11357 16-Dec-15 2015_12 "ENSDARG00000060205(wu:fe18c06),ENSDARG00000061432(LOC798349),ENSDARG00000061496,ENSDARG00000053682" "ENSXETG00000025974(b3gnt5),ENSXETG00000019594(),ENSXETG00000003777(B3GNT4),ENSXETG00000016436(),ENSXETG00000004908()" "learning defective,viable,fertile" FBgn0013673 mt:ATPase8 mitochondrial ATPase subunit 8 http://flybase.net/reports/FBgn0013673.html FBgn0002867 protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" 0015986=ATP synthesis coupled proton transport "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), 0005739=mitochondrion" "atp8, CG34072, ATPase8, ATP8, URF6L, ATPase 8" "IPR001421=ATP synthase protein 8, metazoa" CG34072 16-Dec-15 2015_12 FBgn0013574 l(3)82Fb lethal (3) 82Fb http://flybase.net/reports/FBgn0013574.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" "adult abdomen,adult head" FBgn0002380 l(3)93Bb lethal (3) 93Bb http://flybase.net/reports/FBgn0002380.html gene "l(3)er4, er4" 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0025423 Dl::Nrg Dl::Nrg http://flybase.net/reports/FBgn0025423.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing vein,wing vein L3,wing blade" FBgn0265818 CR44607 http://flybase.net/reports/FBgn0265818.html non_protein_coding_gene lincRNA.15 CR44607 16-Dec-15 2015_12 FBgn0037781 Fancl Fancl http://flybase.net/reports/FBgn0037781.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0006281=DNA repair, 0006513=protein monoubiquitination" 0043240=Fanconi anaemia nuclear complex "CG12812, FANCL, FAL" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019162=Fanconi anemia complex, subunit FancL, WD-repeat containing domain, IPR026850=FANCL C-terminal domain, IPR026848=E3 ubiquitin-protein ligase FANCL" CG12812 16-Dec-15 2015_12 ENSDARG00000007885(fancl) ENSXETG00000020481(FANCL) ENSMUSG00000004018(Fancl) ENSG00000115392(FANCL) "visible,chemical conditional,chemical sensitive,viable" "eye,chemical conditional" DRSC14550 I -1.698582147 0.119800945 0.642479834 0.614919858 -0.255532089 1.083039591 FBgn0002664 mat(2)ea-A maternal effect early arrest A http://flybase.net/reports/FBgn0002664.html gene mat(2)earlyPB28 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0031319 CG4896 http://flybase.net/reports/FBgn0031319.html protein_coding_gene "0008270=zinc ion binding, 0000166=nucleotide binding, 0003729=mRNA binding, 0044822=poly(A) RNA binding" "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005654=nucleoplasm cg4896 "IPR001876=Zinc finger, RanBP2-type, IPR000504=RNA recognition motif domain, IPR015880=Zinc finger, C2H2-like, IPR000467=G-patch domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG4896 16-Dec-15 2015_12 YNL224C(SQS1) WBGene00020346(T08B2.5) ENSXETG00000007303(RBM5) "ENSMUSG00000032580(Rbm5),ENSMUSG00000031060(Rbm10)" "ENSG00000003756(RBM5),ENSG00000182872(RBM10)" "viable,fertile" FBgn0065688 l(2)SH0649 lethal (2) SH0649 http://flybase.net/reports/FBgn0065688.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043853 scaRNA:MeU5-C46 small Cajal body-specific RNA : MeU5-C46 http://flybase.net/reports/FBgn0043853.html FBgn0051504 snoRNA_gene "0005730=nucleolus, 0015030=Cajal body" "MeU5-C46(U85), snoRNA:U85, U85scaRNA, CR32863, snoRNA:MeU5-C46, dU85, chr3R:3298692..3298881, U85 scaRNA, CG31504, small Cajal body-specific RNA U85, U85, U85 small CB-specific RNA, dU85 scaRNA" CR32863 16-Dec-15 2015_12 FBgn0265429 CG44341 http://flybase.net/reports/FBgn0265429.html protein_coding_gene CG44341 16-Dec-15 2015_12 FBgn0263891 l(3)F58 http://flybase.net/reports/FBgn0263891.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0031820 Daxx Daxx-like protein http://flybase.net/reports/FBgn0031820.html protein_coding_gene 0005515=protein binding "0006979=response to oxidative stress, 0042981=regulation of apoptotic process, 0045893=positive regulation of transcription, DNA-templated, 0008340=determination of adult lifespan" "CG9537, Daxx, DLP" IPR005012=Daxx protein CG9537 16-Dec-15 2015_12 ENSMUSG00000002307(Daxx) "viable,short lived,female fertile,reduced,oxidative stress response defective,lethal,visible,increased cell death" "wing,wing disc" FBgn0263389 CG43441 http://flybase.net/reports/FBgn0263389.html protein_coding_gene CG43441 16-Dec-15 2015_12 FBgn0083973 CG34137 http://flybase.net/reports/FBgn0083973.html protein_coding_gene CG34137 16-Dec-15 2015_12 DRSC36514 K 2.001942348 1.745744674 FBgn0260256 GSd316 http://flybase.net/reports/FBgn0260256.html gene 16-Dec-15 2015_12 lethal FBgn0040978 CG7473 http://flybase.net/reports/FBgn0040978.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262782 Mdh1 Malate dehydrogenase 1 http://flybase.net/reports/FBgn0262782.html "FBgn0002699, FBgn0032237" protein_coding_gene 0030060=L-malate dehydrogenase activity "0055114=oxidation-reduction process, 0006108=malate metabolic process, 0046331=lateral inhibition, 0005975=carbohydrate metabolic process" "0005737=cytoplasm, 0005829=cytosol, 0005811=lipid particle, 0005777=peroxisome" "Malic DH, cytoplasmic Mdh, MdhD, Mdh2, sMdh, MDH-1, Mdh-1, CT17038, CG5362, cMdh, Mdh, MDH, Malate dehydrogenase, cytosolic malate dehydrogenase" "IPR022383=Lactate/malate dehydrogenase, C-terminal, IPR001236=Lactate/malate dehydrogenase, N-terminal, IPR015955=Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR001252=Malate dehydrogenase, active site, IPR001557=L-lactate/malate dehydrogenase, IPR016040=NAD(P)-binding domain, IPR010945=Malate dehydrogenase, type 2, IPR011274=Malate dehydrogenase, NAD-dependent, cytosolic" CG5362 16-Dec-15 2015_12 "ENSDARG00000017772(mdh1a),ENSDARG00000044080(mdh1b)" WBGene00018491(F46E10.10) ENSXETG00000013016(MDH1) ENSMUSG00000020321(Mdh1) ENSG00000014641(MDH1) FBgn0039099 GILT2 Gamma-interferon-inducible lysosomal thiol reductase 2 http://flybase.net/reports/FBgn0039099.html FBgn0027761 protein_coding_gene "0015036=disulfide oxidoreductase activity, 0016667=oxidoreductase activity, acting on a sulfur group of donors" "1900426=positive regulation of defense response to bacterium, 0055114=oxidation-reduction process" "Gamma-interferon-inducible lysosomal thiol reductase, anon-EST:Posey120, CG10157, GILT" "IPR012336=Thioredoxin-like fold, IPR004911=Gamma interferon inducible lysosomal thiol reductase GILT" CG10157 16-Dec-15 2015_12 "immune response defective,long lived,viable" FBgn0027054 CSN4 COP9 signalosome subunit 4 http://flybase.net/reports/FBgn0027054.html FBgn0022061 protein_coding_gene "0019784=NEDD8-specific protease activity, 0005515=protein binding, 0044212=transcription regulatory region DNA binding" "0007095=mitotic G2 DNA damage checkpoint, 0048140=male germ-line cyst encapsulation, 0046331=lateral inhibition, 0010388=cullin deneddylation, 0007281=germ cell development, 0032435=negative regulation of proteasomal ubiquitin-dependent protein catabolic process, 0036099=female germ-line stem cell maintenance, 0001751=compound eye photoreceptor cell differentiation, 0050821=protein stabilization, 0000338=protein deneddylation" 0008180=COP9 signalosome "Cops4, Dch4, COP9 signalosome subunit 4, CH4, l(2)k08018, DCH4, csn4, COP9 complex homolog subunit 4, CG8725, Csn4, Drosophila COP9 signalosome homolog 4" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000717=Proteasome component (PCI) domain" CG8725 16-Dec-15 2015_12 ENSDARG00000043732(cops4) WBGene00000816(csn-4) ENSMUSG00000035297(Cops4) ENSG00000138663(COPS4) "lethal,recessive,viable,fertile,female sterile germline-dependent,germline clone,small body,female sterile,chemical sensitive,visible,somatic clone,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage" "ovary,germline clone,female germline stem cell,fusome | germline clone,photoreceptor cell,cephalopharyngeal skeleton,trichogen cell,somatic clone,supernumerary,chaeta,mesothoracic tergum" DRSC07350 K 0.884105131 0.660767784 0.84540905 0.454594417 2.89593059 2.872183253 FBgn0025869 C31 C31 http://flybase.net/reports/FBgn0025869.html gene 0007628=adult walking behavior 16-Dec-15 2015_12 FBgn0035909 ergic53 ergic53 http://flybase.net/reports/FBgn0035909.html "FBgn0020254, FBgn0035910, FBgn0011010" protein_coding_gene 0005537=mannose binding "0016020=membrane, 0012505=endomembrane system" "dergic53, CG6822, l(3)S1760, rhea, dERGIC53, l(3)s1760, ergic-53, ERGIC53" "IPR005052=Legume-like lectin, IPR013320=Concanavalin A-like lectin/glucanase domain" CG6822 16-Dec-15 2015_12 ENSDARG00000069980(lman1) "YLR080W(EMP46),YFL048C(EMP47)" WBGene00002070(ile-1) ENSXETG00000021159(LMAN1) ENSMUSG00000041891(Lman1) ENSG00000074695(LMAN1) "viable,fertile,partially lethal - majority die" FBgn0065132 l(3)SH129 lethal (3) SH129 http://flybase.net/reports/FBgn0065132.html gene l(2)SH3 129 16-Dec-15 2015_12 "lethal,recessive" FBgn0065729 l(2)SH0556 lethal (2) SH0556 http://flybase.net/reports/FBgn0065729.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267904 CG46192 http://flybase.net/reports/FBgn0267904.html protein_coding_gene Mst35Ba-related CG46192 16-Dec-15 2015_12 FBgn0065742 l(2)SH0523 lethal (2) SH0523 http://flybase.net/reports/FBgn0065742.html gene l(2)SH2 0523 16-Dec-15 2015_12 "lethal,recessive" FBgn0060848 l(3)S048619a lethal (3) S048619a http://flybase.net/reports/FBgn0060848.html gene 0486/19 16-Dec-15 2015_12 "lethal,recessive" FBgn0005013 dipp-4 defective in phototaxis plasticity 4 http://flybase.net/reports/FBgn0005013.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0028174 l(3)S026420 lethal (3) S026420 http://flybase.net/reports/FBgn0028174.html gene 0264/20 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0262723 in::mwh http://flybase.net/reports/FBgn0262723.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0020364 anon-17Aa anon-17Aa http://flybase.net/reports/FBgn0020364.html gene "1D10, unnamed" 16-Dec-15 2015_12 FBgn0024141 Bip-p150 Bcd interacting protein p150 http://flybase.net/reports/FBgn0024141.html gene p150 16-Dec-15 2015_12 FBgn0067104 G5.A G5.A http://flybase.net/reports/FBgn0067104.html gene G5 16-Dec-15 2015_12 "visible,lethal" chaeta FBgn0043984 Su(rst)E304 Su(rst)E304 http://flybase.net/reports/FBgn0043984.html gene 0001745=compound eye morphogenesis E304 16-Dec-15 2015_12 viable FBgn0013499 l(1)LB5 lethal (1) LB5 http://flybase.net/reports/FBgn0013499.html gene LB5 16-Dec-15 2015_12 lethal FBgn0265652 CR44459 http://flybase.net/reports/FBgn0265652.html non_protein_coding_gene lincRNA.316 CR44459 16-Dec-15 2015_12 FBgn0041769 anon-d35 anon-d35 http://flybase.net/reports/FBgn0041769.html gene d35 16-Dec-15 2015_12 FBgn0032127 CG13114 http://flybase.net/reports/FBgn0032127.html protein_coding_gene 0042600=chorion CG13114 16-Dec-15 2015_12 viable FBgn0044399 Scim28 Sensitized chromosome inheritance modifier 28 http://flybase.net/reports/FBgn0044399.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0266820 CR45282 http://flybase.net/reports/FBgn0266820.html non_protein_coding_gene CR45282 16-Dec-15 2015_12 FBgn0045497 Gr22e Gustatory receptor 22e http://flybase.net/reports/FBgn0045497.html "FBgn0045494, FBgn0051936" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 2940.1, GR22e, Gr2940.1, CG31936" IPR013604=7TM chemoreceptor CG31936 16-Dec-15 2015_12 viable DRSC20912 IE 1.536077611 0.764820933 -4.568871423 1.353590474 -0.063108385 0.452981509 FBgn0259666 B0729 http://flybase.net/reports/FBgn0259666.html gene 16-Dec-15 2015_12 visible wing FBgn0267489 PRY polycystine-related-Y http://flybase.net/reports/FBgn0267489.html "FBgn0044023, FBan0040930, FBgn0085538, FBgn0261334, FBan0041367, FBgn0085633, FBgn0267434" protein_coding_gene 0016020=membrane "CG42619, CG45787, CG41367, CG40930" "IPR001024=PLAT/LH2 domain, IPR002859=PKD/REJ-like domain, IPR000203=GPS motif" CG45787 16-Dec-15 2015_12 FBgn0031632 CG15628 http://flybase.net/reports/FBgn0031632.html FBgn0066039 protein_coding_gene 0008080=N-acetyltransferase activity anon-WO02059370.23 "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain, IPR013653=FR47-like" CG15628 16-Dec-15 2015_12 "viable,fertile,body color defective" mesothoracic tergum DRSC00256 K 0.266786191 1.84930585 FBgn0026080 Tip60 Tat interactive protein 60kDa http://flybase.net/reports/FBgn0026080.html protein_coding_gene 0004402=histone acetyltransferase activity "0043967=histone H4 acetylation, 0016573=histone acetylation, 2000331=regulation of terminal button organization, 0007399=nervous system development, 0010468=regulation of gene expression, 0048167=regulation of synaptic plasticity, 0006355=regulation of transcription, DNA-templated, 0043524=negative regulation of neuron apoptotic process, 0006974=cellular response to DNA damage stimulus, 0043486=histone exchange" "0035267=NuA4 histone acetyltransferase complex, 0005705=polytene chromosome interband, 0005634=nucleus, 0000123=histone acetyltransferase complex" "DmEG0007.7, EG0007.7, 6121, Dmel/TIP60, dmHAG405, TIP60, Tat-interactive protein-60 KDa, dTIP60, Tat-interactive protein, CG6121, EG:EG0007.7, dTip60, TIP-60, Tip60, Dmel\TIP60" "IPR016181=Acyl-CoA N-acyltransferase, IPR002717=Histone acetyltransferase domain, MYST-type, IPR025995=RNA binding activity-knot of a chromodomain, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain" CG6121 16-Dec-15 2015_12 "ENSDARG00000045951(htatip),ENSDARG00000004587(zgc:92510)" YOR244W(ESA1) WBGene00007029(mys-1) ENSMUSG00000024926(Kat5) ENSG00000172977(KAT5) "locomotor behavior defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,majority die during third instar larval stage,increased mortality during development,partially lethal - majority die,increased cell death,viable,heat sensitive,visible,fertile,partially,cytokinesis defective,cell lethal" "terminal bouton,type I bouton,ectopic,type Ib terminal bouton | ectopic,terminal boutonMef2.247,type Ib terminal bouton | ectopicMef2.247,type Is terminal boutonMef2.247,embryonic/larval brain | third instar larval stage,wing,wing vein,wing disc,trichogen cell" DRSC18661 E -0.55123146 -0.745855978 2.891373343 -2.462615533 0.773167995 -0.238591028 FBgn0083286 E(smoDN)2117 Enhancer of smoDN 2117 http://flybase.net/reports/FBgn0083286.html gene 16-Dec-15 2015_12 FBgn0001794 l(1)Mb26 lethal (1) Mb26 http://flybase.net/reports/FBgn0001794.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0261707 CR42743 http://flybase.net/reports/FBgn0261707.html non_protein_coding_gene CR42743 16-Dec-15 2015_12 FBgn0032595 CG17996 http://flybase.net/reports/FBgn0032595.html FBgn0063192 protein_coding_gene BcDNA:GM20557 IPR013892=Cytochrome c oxidase biogenesis protein Cmc1-like CG17996 16-Dec-15 2015_12 ENSDARG00000042996(zgc:77499) WBGene00017159(F01F1.2) ENSXETG00000026985(CMC1) ENSMUSG00000039163(Cmc1) ENSG00000187118(CMC1) FBgn0052268 Drsl6 Drosomycin-like 6 http://flybase.net/reports/FBgn0052268.html "FBgn0035441, FBgn0035442" protein_coding_gene "0050832=defense response to fungus, 0006952=defense response" 0005576=extracellular region "dro6, drosomycin, Drs-lI, drosomycin-I, Drosomycin-like I, Dro6, Drosomycin-6, Drosomycin 6, Dro-I, CG11520, drosomycin-6, CG10815, CG32268" "IPR003614=Knottin, scorpion toxin-like" CG32268 16-Dec-15 2015_12 viable FBgn0267378 sau sauron http://flybase.net/reports/FBgn0267378.html "FBgn0083064, FBgn0010704, FBgn0031402, FBgn0046260, FBgn0047216" protein_coding_gene "0017137=Rab GTPase binding, 0070300=phosphatidic acid binding, 0070273=phosphatidylinositol-4-phosphate binding, 0010314=phosphatidylinositol-5-phosphate binding, 0032266=phosphatidylinositol-3-phosphate binding" "0007112=male meiosis cytokinesis, 0007030=Golgi organization, 0007224=smoothened signaling pathway, 0007111=meiosis II cytokinesis, 0007053=spindle assembly involved in male meiosis, 0000281=mitotic cytokinesis, 0000915=actomyosin contractile ring assembly, 0000301=retrograde transport, vesicle recycling within Golgi, 0036089=cleavage furrow formation, 0090307=mitotic spindle assembly, 0007110=meiosis I cytokinesis, 0051225=spindle assembly" "0031985=Golgi cisterna, 0032154=cleavage furrow, 0005794=Golgi apparatus" "rti, BEST:LD28579, rotini, BcDNA:LD10657, CG7085, l(2)s5379, GOLPH3, lethal (2) s5379" IPR008628=Golgi phosphoprotein 3 CG7085 16-Dec-15 2015_12 "ENSDARG00000044225(LOC561662),ENSDARG00000052851(golph3)" YDR372C(VPS74) WBGene00021644(Y47G6A.18) ENSXETG00000008912(golph3l) ENSMUSG00000022200(Golph3) ENSG00000113384(GOLPH3) DRSC00694 I 0.424452961 1.969527731 0.931347088 0.324340516 -0.114453286 0.197195454 FBgn0035401 CG1291 http://flybase.net/reports/FBgn0035401.html protein_coding_gene "0033164=glycolipid 6-alpha-mannosyltransferase activity, 0004376=glycolipid mannosyltransferase activity, 0004378=GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity" 0009058=biosynthetic process "0012505=endomembrane system, 0005811=lipid particle" "Alg2, dAlg2" "IPR028098=Glycosyltransferase subfamily 4-like, N-terminal domain, IPR001296=Glycosyl transferase, family 1, IPR027054=Alpha-1,3/1,6-mannosyltransferase ALG2" CG1291 16-Dec-15 2015_12 ENSDARG00000070399(alg2) YGL065C(ALG2) WBGene00017282(F09E5.2) ENSXETG00000011972(alg2) ENSMUSG00000039740(Alg2) ENSG00000119523(ALG2) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0034693 CG11073 http://flybase.net/reports/FBgn0034693.html protein_coding_gene CG11073 16-Dec-15 2015_12 "viable,fertile" DRSC04087 K 0.032397861 0.606218717 0.834528238 0.087522026 0.469254622 1.876953573 FBgn0002242 l(3)68Cd lethal (3) 68Cd http://flybase.net/reports/FBgn0002242.html gene "l(3)rsg3, rsg3, l(3)Bl[D], rose-gespleten region interval 3" 16-Dec-15 2015_12 lethal FBgn0032445 CG6153 http://flybase.net/reports/FBgn0032445.html protein_coding_gene 0006974=cellular response to DNA damage stimulus 6153 "IPR008979=Galactose-binding domain-like, IPR010400=PITH domain" CG6153 16-Dec-15 2015_12 ENSDARG00000032211(zgc:77241) WBGene00022704(ZK353.9) ENSXETG00000025529(C1orf128) ENSMUSG00000028669(1110049F12Rik) ENSG00000057757(PITHD1) viable FBgn0012011 tRNA:V4:89BC transfer RNA:val4:89BC http://flybase.net/reports/FBgn0012011.html "FBgn0012007, FBgn0051587, FBgn0060030" tRNA_gene "0033449=GUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:V4, tRNA[Val][[4]], tRNA-Val-4, tRNA:V:AAC:AE002708-a, val-tRNA-4, chr3R.trna13-ValAAC, tRNA[Val-AAC], tRNA:val4:89BC, CR31587, AE002708.trna7-ValAAC, valine tRNA" CR31587 16-Dec-15 2015_12 FBgn0266650 CR45157 http://flybase.net/reports/FBgn0266650.html non_protein_coding_gene CR45157 16-Dec-15 2015_12 FBgn0086025 snoRNA:Me28S-A2589c http://flybase.net/reports/FBgn0086025.html snoRNA_gene "CR34654, Me28S-Am2589c, chr2R:16839179..16839292" CR34654 16-Dec-15 2015_12 FBgn0003229 ref(1)H refractory to sigma H http://flybase.net/reports/FBgn0003229.html gene Ref(1)H 16-Dec-15 2015_12 FBgn0000951 Fs(2)Bil Female sterile (2) Billa http://flybase.net/reports/FBgn0000951.html gene "Fs(2)Sz2, Billa" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant" "dorsal appendage,egg" FBgn0029759 CG12732 http://flybase.net/reports/FBgn0029759.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267127 CR45567 http://flybase.net/reports/FBgn0267127.html non_protein_coding_gene CR45567 16-Dec-15 2015_12 FBgn0261514 NimA Nimrod A http://flybase.net/reports/FBgn0261514.html "FBgn0259177, FBgn0051765, FBgn0028937, FBgn0051841, FBgn0001277" protein_coding_gene 0006909=phagocytosis 0016021=integral component of membrane "jaunty, CG42282, nimrod A, CG8855, DS00180.5, CG31765, BG:DS00180.5, CT25428, CG31841, j, nimA, NimA" "IPR000742=EGF-like domain, IPR011489=EMI domain, IPR013032=EGF-like, conserved site" CG42282 16-Dec-15 2015_12 FBgn0063499 GstE10 Glutathione S transferase E10 http://flybase.net/reports/FBgn0063499.html FBgn0034334 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "gste10, DmGSTE10, CG17522, GSTE10" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal" CG17522 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0039004 Nup133 Nucleoporin 133kD http://flybase.net/reports/FBgn0039004.html protein_coding_gene 0005487=nucleocytoplasmic transporter activity "0007184=SMAD protein import into nucleus, 0006406=mRNA export from nucleus" 0031080=nuclear pore outer ring "Nup 133, Nucleoporin 133, nup133, CG6958" "IPR007187=Nucleoporin, Nup133/Nup155-like, C-terminal, IPR015943=WD40/YVTN repeat-like-containing domain, IPR014908=Nucleoporin, Nup133/Nup155-like, N-terminal" CG6958 16-Dec-15 2015_12 ENSDARG00000010078(nup133) ENSXETG00000001244(NUP133) ENSMUSG00000039509(Nup133) ENSG00000069248(NUP133) FBgn0082619 S(CycEJP)59S18 S(CycEJP)59S18 http://flybase.net/reports/FBgn0082619.html gene 59S18 16-Dec-15 2015_12 "lethal,recessive" FBgn0263109 CG43366 http://flybase.net/reports/FBgn0263109.html "FBgn0033045, FBgn0033046" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005615=extracellular space "CG14470, CG12551" "IPR000215=Serpin family, IPR023796=Serpin domain, IPR023795=Serpin, conserved site" CG43366 16-Dec-15 2015_12 DRSC25725 K -0.397217175 0.111318732 0.936519971 0.637256728 1.893891475 -0.476813472 FBgn0259360 EP-614 http://flybase.net/reports/FBgn0259360.html gene 16-Dec-15 2015_12 visible wing FBgn0051816 CG31816 http://flybase.net/reports/FBgn0051816.html "FBgn0045096, FBgn0045237, FBgn0045332" protein_coding_gene "NEST:bs19f07, NEST:bs11b11, NEST:bs34h07" CG31816 16-Dec-15 2015_12 viable DRSC01547 I -0.357568355 -1.569204021 -0.36647446 0.419010155 0.299510954 0.072152828 FBgn0016807 l(1)K9 lethal (1) K9 http://flybase.net/reports/FBgn0016807.html gene K9 16-Dec-15 2015_12 "lethal,recessive" FBgn0023140 WppC White prepupal locus C http://flybase.net/reports/FBgn0023140.html gene "3, 12, 6" 16-Dec-15 2015_12 FBgn0263617 CR43626 http://flybase.net/reports/FBgn0263617.html non_protein_coding_gene CR43626 16-Dec-15 2015_12 FBgn0060847 l(3)S048716b lethal (3) S048716b http://flybase.net/reports/FBgn0060847.html gene 0487/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0025746 l(3)99Fa lethal (3) 99Fa http://flybase.net/reports/FBgn0025746.html gene 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" FBgn0026222 l(3)03608 lethal (3) 03608 http://flybase.net/reports/FBgn0026222.html gene 16-Dec-15 2015_12 lethal FBgn0029523 CR18275 http://flybase.net/reports/FBgn0029523.html pseudogene_attribute CG18275 CR18275 16-Dec-15 2015_12 "lethal,partially lethal - majority die" FBgn0043980 Su(rst)J45 Su(rst)J45 http://flybase.net/reports/FBgn0043980.html gene 0001745=compound eye morphogenesis J45 16-Dec-15 2015_12 FBgn0008646 E5 E5 http://flybase.net/reports/FBgn0008646.html FBgn0038187 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus CG9930 "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG9930 16-Dec-15 2015_12 WBGene00000446(ceh-23) ENSXETG00000011780(NOTO) ENSMUSG00000024986(Hhex) "ENSG00000135638(EMX1),ENSG00000170370(EMX2)" viable FBgn0033603 Cpr47Ef Cuticular protein 47Ef http://flybase.net/reports/FBgn0033603.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr47Ef, CG13214" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG13214 16-Dec-15 2015_12 FBgn0032843 CG10730 http://flybase.net/reports/FBgn0032843.html protein_coding_gene 0003824=catalytic activity "0032504=multicellular organism reproduction, 0008152=metabolic process" 0005615=extracellular space "38B.7, gi7298655, gi21430366" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG10730 16-Dec-15 2015_12 viable FBgn0000458 dis distorted eye http://flybase.net/reports/FBgn0000458.html gene 16-Dec-15 2015_12 visible "eye,macrochaeta,wing,wing vein" FBgn0039071 CG4434 http://flybase.net/reports/FBgn0039071.html protein_coding_gene 0004353=glutamate dehydrogenase [NAD(P)+] activity "0055114=oxidation-reduction process, 0019551=glutamate catabolic process to 2-oxoglutarate" 0005759=mitochondrial matrix "IPR006097=Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain, IPR014362=Glutamate dehydrogenase, IPR006096=Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal, IPR006095=Glutamate/phenylalanine/leucine/valine dehydrogenase, IPR016040=NAD(P)-binding domain" CG4434 16-Dec-15 2015_12 "YAL062W(GDH3),YOR375C(GDH1)" viable FBgn0266405 CR45045 http://flybase.net/reports/FBgn0266405.html non_protein_coding_gene CR45045 16-Dec-15 2015_12 FBgn0027646 l(2)k09017a lethal (2) k09017a http://flybase.net/reports/FBgn0027646.html gene 16-Dec-15 2015_12 lethal FBgn0029696 CG15571 http://flybase.net/reports/FBgn0029696.html protein_coding_gene 0007306=eggshell chorion assembly 0042600=chorion CG15571 16-Dec-15 2015_12 viable FBgn0011153 l(1)Q231 lethal (1) Q231 http://flybase.net/reports/FBgn0011153.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0084515 S16.6 S16.6 http://flybase.net/reports/FBgn0084515.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0069202 l(2)46Fb lethal (2) 46Fb http://flybase.net/reports/FBgn0069202.html "FBgn0019716, FBgn0019721" gene "10.5, Complementation group B, 6.6, unnamed, l(2)46CFg, l(2)46CFl, 15.4, B complementation group, B" 16-Dec-15 2015_12 "lethal,recessive,semidominant" FBgn0001878 l(1)YD23a lethal (1) YD23a http://flybase.net/reports/FBgn0001878.html gene l(1)YD23 16-Dec-15 2015_12 lethal FBgn0266514 s-535 http://flybase.net/reports/FBgn0266514.html gene 16-Dec-15 2015_12 FBgn0027651 l(2)44A lethal (2) 44A http://flybase.net/reports/FBgn0027651.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0263316 Mrp4 Multidrug resistance protein 4 ortholog http://flybase.net/reports/FBgn0263316.html "FBgn0025701, FBgn0037914, FBgn0046311, FBgn0044463" protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0008514=organic anion transmembrane transporter activity, 0005524=ATP binding" "0006855=drug transmembrane transport, 0001666=response to hypoxia, 0048190=wing disc dorsal/ventral pattern formation, 0034059=response to anoxia" 0043190=ATP-binding cassette (ABC) transporter complex "unnamed, dMRP4, EP3221, BEST:CK01227, CK01227, BEST:CK02472, CG14709, Dme_CG14709" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain" CG14709 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) FBgn0001162 gustM gustatory-defective M http://flybase.net/reports/FBgn0001162.html gene 16-Dec-15 2015_12 taste perception defective FBgn0067775 fragile-locus-A fragile locus A http://flybase.net/reports/FBgn0067775.html gene 0007343=egg activation 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0002454 mdm many discs missing http://flybase.net/reports/FBgn0002454.html FBgn0011654 gene "l(3)J16, l(3)SG7" 16-Dec-15 2015_12 "some die during larval stage,lethal - all die before end of larval stage,recessive" imaginal disc FBgn0267677 CR46013 http://flybase.net/reports/FBgn0267677.html non_protein_coding_gene CR46013 16-Dec-15 2015_12 FBgn0013690 mt:tRNA:C mitochondrial cysteine tRNA http://flybase.net/reports/FBgn0013690.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "tRNA-Cys, tRNA[Cys], mtdbD00006296, CR34065, tRNAcys" CR34065 16-Dec-15 2015_12 FBgn0058112 CG40112 http://flybase.net/reports/FBgn0058112.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265933 CR44722 http://flybase.net/reports/FBgn0265933.html non_protein_coding_gene lincRNA.508 CR44722 16-Dec-15 2015_12 FBgn0000366 cr-3 cream 3 http://flybase.net/reports/FBgn0000366.html gene cream in chromosome 3 16-Dec-15 2015_12 "eye color defective,recessive" "Malpighian tubule,pigment cell" FBgn0038820 CG4000 http://flybase.net/reports/FBgn0038820.html protein_coding_gene CG4000 16-Dec-15 2015_12 "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0020305 dbe dribble http://flybase.net/reports/FBgn0020305.html "FBgn0022118, FBgn0022171, FBgn0024894" protein_coding_gene 0003723=RNA binding "0006364=rRNA processing, 0040018=positive regulation of multicellular organism growth" "0005654=nucleoplasm, 0005730=nucleolus" "l(2)k06708, dribble, DBE, l(2)k05428, Dribble, CG4258" "IPR004087=K Homology domain, IPR024166=Ribosomal RNA assembly KRR1, IPR004088=K Homology domain, type 1" CG4258 16-Dec-15 2015_12 ENSDARG00000011246(zgc:136398) YCL059C(KRR1) WBGene00015461(C05C8.2) ENSXETG00000013312(TGas090c24.1) ENSMUSG00000063334(Krr1) ENSG00000111615(KRR1) "lethal,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "ovariole,germline clone,mesothoracic tergum" FBgn0087002 Rfabg Retinoid- and fatty acid-binding glycoprotein http://flybase.net/reports/FBgn0087002.html "FBgn0016724, FBgn0021778" protein_coding_gene "0008017=microtubule binding, 0005504=fatty acid binding, 0019841=retinol binding, 0005501=retinoid binding, 0020037=heme binding, 0005102=receptor binding, 0005319=lipid transporter activity, 0005198=structural molecule activity" "0007224=smoothened signaling pathway, 0006869=lipid transport, 0006810=transport, 0016055=Wnt signaling pathway" "0005875=microtubule associated complex, 0005615=extracellular space, 0030139=endocytic vesicle, 0045178=basal part of cell, 0005811=lipid particle, 0005576=extracellular region" "CG11064, ApoLII, Retinoid- and Fatty Acid-binding Glycoprotein, Retinoid- and fatty-acid binding protein, apolipophorin II, ApoL1, retinoid-fatty acid binding protein, Lpp, retinoid- and fatty acid-binding glycoprotein, retinoid- and fatty acid-binding gene, T3, apoLII, RfaBP, apoLpp, chr4:1088013..1088173, RfaBp, Retinoid- and fatty acid-binding protein, Lipophorin, Retinoid and fatty-acid binding protein, Retinoid and Fatty Acid Binding Glycoprotein, apolipophorin, Apolipophorin, apolpp, apoLPP, retinoid and fatty acid binding protein, apoLI, apolipophorin-2, RFABG, ApoLI, ApoL2, RFABP, DRBP, lipophorin, apolipophorin I, rfabg, RFBP" "IPR001846=von Willebrand factor, type D domain, IPR011030=Vitellinogen, superhelical, IPR015816=Vitellinogen, beta-sheet N-terminal, IPR001747=Lipid transport protein, N-terminal, IPR015819=Lipid transport protein, beta-sheet shell, IPR015255=Vitellinogen, open beta-sheet, IPR015817=Vitellinogen, open beta-sheet, subdomain 1, IPR009454=Lipid transport, open beta-sheet, IPR015818=Vitellinogen, open beta-sheet, subdomain 2" CG11064 16-Dec-15 2015_12 "ENSDARG00000022767(apobl),ENSDARG00000042780(apob)" "WBGene00006925(vit-1),WBGene00006929(vit-5),WBGene00006928(vit-4),WBGene00006927(vit-3),WBGene00006926(vit-2),WBGene00006930(vit-6)" FBgn0263234 Phae1 Phaedra 1 http://flybase.net/reports/FBgn0263234.html "FBgn0029136, FBgn0032412" protein_coding_gene "0004222=metalloendopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "SP134, CG16996" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG16996 16-Dec-15 2015_12 FBgn0266634 CR45141 http://flybase.net/reports/FBgn0266634.html non_protein_coding_gene CR45141 16-Dec-15 2015_12 FBgn0067861 Sdic1 Sperm-specific dynein intermediate chain 1 http://flybase.net/reports/FBgn0067861.html "FBgn0025801, FBgn0031095" protein_coding_gene 0003777=microtubule motor activity 0007018=microtubule-based movement "0036126=sperm flagellum, 0005858=axonemal dynein complex" "Sdic:CG9580, CG9580" "IPR025956=Cytoplasmic dynein 1 intermediate chain 1/2, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG9580 16-Dec-15 2015_12 "ENSDARG00000005756(dync1i2a),ENSDARG00000022487,ENSDARG00000060948(zgc:158394),ENSDARG00000063383(dync1i2b)" YDR488C(PAC11) WBGene00015927(dyci-1) "ENSXETG00000020285(dnci2),ENSXETG00000020277(DYNC1I1)" "ENSMUSG00000027012(Dync1i2),ENSMUSG00000029757(Dync1i1)" "ENSG00000077380(DYNC1I2),ENSG00000158560(DYNC1I1)" FBgn0265682 CR44489 http://flybase.net/reports/FBgn0265682.html non_protein_coding_gene lincRNA.183 CR44489 16-Dec-15 2015_12 FBgn0044385 Scim9 Sensitized chromosome inheritance modifier 9 http://flybase.net/reports/FBgn0044385.html gene "0007067=mitotic nuclear division, 0016321=female meiosis chromosome segregation, 0007062=sister chromatid cohesion" 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant,partially lethal - majority die,recessive,mitotic cell cycle defective" "mitosis & nuclear chromosome,nuclear chromosome" FBgn0266911 CR45371 http://flybase.net/reports/FBgn0266911.html non_protein_coding_gene CR45371 16-Dec-15 2015_12 FBgn0001433 l(1)air7 lethal aberrant immune response 7 http://flybase.net/reports/FBgn0001433.html gene "RC61, jnR3, l(1)jnR3, air7, l(1)7Ac, l(1)air[7]" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,cell lethal,germline clone" FBgn0030186 CG2962 http://flybase.net/reports/FBgn0030186.html protein_coding_gene CG2962 16-Dec-15 2015_12 viable FBgn0011199 l(1)304-69 lethal (1) 304-69 http://flybase.net/reports/FBgn0011199.html FBgn0010203 gene 304-69 16-Dec-15 2015_12 "lethal,recessive" FBgn0051721 Trim9 Tripartite motif containing 9 http://flybase.net/reports/FBgn0051721.html "FBgn0032267, FBgn0032270" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0016199=axon midline choice point recognition, 0038007=netrin-activated signaling pathway, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0007411=axon guidance, 0022008=neurogenesis, 0007409=axonogenesis" 0005622=intracellular "Asap, Trim9, Anomalies in sensory axon patterning, CG6256, dTrim9, CG13145, CG31721, asap" "IPR003649=B-box, C-terminal, IPR001870=B30.2/SPRY domain, IPR013783=Immunoglobulin-like fold, IPR001841=Zinc finger, RING-type, IPR003961=Fibronectin type III, IPR017903=COS domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000315=B-box-type zinc finger, IPR003877=SPRY domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG31721 16-Dec-15 2015_12 "ENSDARG00000039123(trim9),ENSDARG00000002226(LOC100332164)" WBGene00016539(madd-2) "ENSXETG00000016487(TRIM9),ENSXETG00000022539(TRIM67)" "ENSMUSG00000036913(Trim67),ENSMUSG00000021071(Trim9)" "ENSG00000119283(TRIM67),ENSG00000100505(TRIM9)" "neuroanatomy defective,viable,fertile,locomotor behavior defective,somatic clone,lethal,visible" "ventral nerve cord commissure,class IV dendritic arborizing neuron,wing,dopaminergic neuron,midline crossing tract,ventral multidendritic neuron vdaB,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,somatic clone | third instar larval stage,ectopic,ganglion mother cell,trichogen cell" DRSC02242 E 0.144096503 -0.063856244 -1.89865789 0.494458012 -0.111217673 -0.770306922 FBgn0083299 E(smoDN)1824 Enhancer of smoDN 1824 http://flybase.net/reports/FBgn0083299.html gene 16-Dec-15 2015_12 FBgn0085307 CG34278 http://flybase.net/reports/FBgn0085307.html protein_coding_gene CG34278 16-Dec-15 2015_12 FBgn0027332 l(1)G0013 lethal (1) G0013 http://flybase.net/reports/FBgn0027332.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060811 l(3)S054515 lethal (3) S054515 http://flybase.net/reports/FBgn0060811.html gene 0545/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0052391 CG32391 http://flybase.net/reports/FBgn0052391.html protein_coding_gene CG32391 16-Dec-15 2015_12 FBgn0003143 pra prawny abdomen http://flybase.net/reports/FBgn0003143.html gene 16-Dec-15 2015_12 "visible,viable,poor" "adult thorax,adult abdomen,wing" FBgn0016925 run::Hsap\CBFA2 CBFA2 http://flybase.net/reports/FBgn0016925.html engineered_fusion_gene run::Hsap\AML1 16-Dec-15 2015_12 FBgn0026377 RalBp-like Retinal-binding protein like http://flybase.net/reports/FBgn0026377.html gene 0005501=retinoid binding 0005737=cytoplasm 16-Dec-15 2015_12 FBgn0063397 Stalker2\ORF2 ORF2 http://flybase.net/reports/FBgn0063397.html transposable_element_gene rom\ORF2 16-Dec-15 2015_12 FBgn0085427 CG34398 http://flybase.net/reports/FBgn0085427.html "FBgn0040961, FBgn0032073" protein_coding_gene "CG9487, CG15867" CG34398 16-Dec-15 2015_12 "viable,visible" "anterior crossvein,wing" FBgn0261995 CG42813 http://flybase.net/reports/FBgn0261995.html "FBgn0051063, FBan0031063, FBgn0039496" protein_coding_gene "0016818=hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, 0046872=metal ion binding" "CG6001, CG31063, Nudix" "IPR004385=Nucleoside diphosphate pyrophosphatase, IPR015797=NUDIX hydrolase domain-like, IPR000086=NUDIX hydrolase domain" CG42813 16-Dec-15 2015_12 FBgn0035734 CG14823 http://flybase.net/reports/FBgn0035734.html protein_coding_gene 0003796=lysozyme activity IPR008597=Destabilase CG14823 16-Dec-15 2015_12 FBgn0040045 CR12460 http://flybase.net/reports/FBgn0040045.html "FBan0012460, FBgn0058051" pseudogene_attribute "CG40051, CG12460" CR12460 16-Dec-15 2015_12 DRSC20970 I 2.040637879 1.564803824 0.689333008 1.191313271 0.460100374 0.36200166 FBgn0265448 CR44348 http://flybase.net/reports/FBgn0265448.html non_protein_coding_gene CR44348 16-Dec-15 2015_12 FBgn0031683 CG4230 http://flybase.net/reports/FBgn0031683.html protein_coding_gene CG4230 16-Dec-15 2015_12 viable FBgn0066328 rijiy rijiy http://flybase.net/reports/FBgn0066328.html gene "0007611=learning or memory, 0008355=olfactory learning" rijiy I 16-Dec-15 2015_12 "learning defective,memory defective" FBgn0060401 l(3)S131404 lethal (3) S131404 http://flybase.net/reports/FBgn0060401.html gene 1314/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031128 hydra hydra http://flybase.net/reports/FBgn0031128.html protein_coding_gene CG1338 IPR022079=Protein of unknown function DUF3629 CG1338 16-Dec-15 2015_12 viable FBgn0033778 CG3790 http://flybase.net/reports/FBgn0033778.html protein_coding_gene 0015226=carnitine transmembrane transporter activity "0045471=response to ethanol, 0055085=transmembrane transport" 0016021=integral component of membrane "carnitine transporter, CT" "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG3790 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" WBGene00003842(oct-1) "viable,fertile" FBgn0036155 CG6163 http://flybase.net/reports/FBgn0036155.html protein_coding_gene IPR006578=MADF domain CG6163 16-Dec-15 2015_12 viable FBgn0060838 l(3)S049604 lethal (3) S049604 http://flybase.net/reports/FBgn0060838.html gene 0496/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0015277 Pi3K59F Phosphotidylinositol 3 kinase 59F http://flybase.net/reports/FBgn0015277.html protein_coding_gene "0016303=1-phosphatidylinositol-3-kinase activity, 0046934=phosphatidylinositol-4,5-bisphosphate 3-kinase activity, 0035005=1-phosphatidylinositol-4-phosphate 3-kinase activity, 0035004=phosphatidylinositol 3-kinase activity" "0006897=endocytosis, 0006914=autophagy, 0033227=dsRNA transport, 0010506=regulation of autophagy, 0045850=positive regulation of nurse cell apoptotic process, 0046854=phosphatidylinositol phosphorylation, 0009267=cellular response to starvation, 0048015=phosphatidylinositol-mediated signaling, 0016322=neuron remodeling, 0035096=larval midgut cell programmed cell death" "0035032=phosphatidylinositol 3-kinase complex, class III, 0000421=autophagic vacuole membrane, 0034271=phosphatidylinositol 3-kinase complex, class III, type I, 0005769=early endosome" "PI3K-59F, dVps34, PI3-kinase, PI[[3]]K, dPI3K, PI3K_59F, CG5373, PI3K, vps34, dPI 3-kinase, PI(3)K, PI 3-kinase, DmVps34, Vps34, dVps34/PI3K59F, VPS34, Pi3K_59F" "IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR011009=Protein kinase-like domain, IPR000008=C2 domain, IPR001263=Phosphoinositide 3-kinase, accessory (PIK) domain, IPR002420=Phosphatidylinositol 3-kinase, C2 domain, IPR016024=Armadillo-type fold, IPR015433=Phosphatidylinositol Kinase, IPR008290=Phosphatidylinositol 3-kinase, Vps34 type" CG5373 16-Dec-15 2015_12 ENSDARG00000054829(pik3c3) YLR240W(VPS34) WBGene00006932(vps-34) ENSXETG00000010280(PIK3C3) ENSMUSG00000033628(Pik3c3) ENSG00000078142(PIK3C3) "viable,fertile,lethal,starvation stress response defective" "autophagic vacuole | conditional | somatic clone,lysosome | conditional | somatic clone,embryonic/larval fat body,conditional,somatic clone,garland cell,eye disc,autophagic vacuole | somatic clone,nurse cell,germline clone,somatic clone | third instar larval stage,pre-autophagosomal structure membrane | conditional | somatic clone,embryonic/larval fat body | late third instar larval stage" DRSC04640 K -0.456494315 -0.055820369 0.033462154 0.123662986 0.505035764 1.581710572 FBgn0004535 l(4)102ABg lethal (4) 102ABg http://flybase.net/reports/FBgn0004535.html gene l(4)24 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0032754 CG10700 http://flybase.net/reports/FBgn0032754.html protein_coding_gene "0008937=ferredoxin-NAD(P) reductase activity, 0051537=2 iron, 2 sulfur cluster binding, 0050660=flavin adenine dinucleotide binding" "0055114=oxidation-reduction process, 0045454=cell redox homeostasis" "IPR004099=Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR016156=FAD/NAD-linked reductase, dimerisation domain, IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR017941=Rieske [2Fe-2S] iron-sulphur domain" CG10700 16-Dec-15 2015_12 ENSDARG00000062780(LOC100150876) WBGene00017640(F20D6.11) ENSXETG00000008277(AIFM3) ENSMUSG00000022763(Aifm3) ENSG00000183773(AIFM3) FBgn0267221 CR45661 http://flybase.net/reports/FBgn0267221.html non_protein_coding_gene CR45661 16-Dec-15 2015_12 FBgn0040269 T:SS-wg Signal sequence of wg http://flybase.net/reports/FBgn0040269.html engineered_tag "T:wg, wingless signal sequence" 16-Dec-15 2015_12 FBgn0036546 elgi early girl http://flybase.net/reports/FBgn0036546.html protein_coding_gene "0016881=acid-amino acid ligase activity, 0008270=zinc ion binding, 0031386=protein tag, 0017022=myosin binding, 0004842=ubiquitin-protein transferase activity" "0000209=protein polyubiquitination, 0051445=regulation of meiotic cell cycle" "early girl, elgi, CG17033" "IPR018957=Zinc finger, C3HC4 RING-type, IPR015036=USP8 interacting, IPR008974=TRAF-like, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013323=SIAH-type domain" CG17033 16-Dec-15 2015_12 ENSDARG00000036831(rnf41) ENSXETG00000009498(RNF41) ENSMUSG00000025373(Rnf41) ENSG00000181852(RNF41) "partially lethal - majority die,visible" "mesothoracic tergum,oocyte" DRSC10242 K -0.14044362 0.160000067 -0.497540236 0.464587119 2.217056269 0.745057763 FBgn0267417 CG45770 http://flybase.net/reports/FBgn0267417.html protein_coding_gene CG45770 16-Dec-15 2015_12 FBgn0267812 CR46137 http://flybase.net/reports/FBgn0267812.html non_protein_coding_gene CR46137 16-Dec-15 2015_12 FBgn0005587 anon-alaA anon-alaA http://flybase.net/reports/FBgn0005587.html FBgn0004553 repeat_region "ala-A, ALA-repeat, ALA-A" 16-Dec-15 2015_12 FBgn0085563 CG41233 http://flybase.net/reports/FBgn0085563.html FBan0041233 protein_coding_gene 16-Dec-15 2015_12 FBgn0264349 CR43805 http://flybase.net/reports/FBgn0264349.html non_protein_coding_gene CR43805 16-Dec-15 2015_12 FBgn0036860 CG14086 http://flybase.net/reports/FBgn0036860.html protein_coding_gene CG14086 16-Dec-15 2015_12 viable FBgn0053388 5SrRNA:CR33388 5SrRNA:CR33388 http://flybase.net/reports/FBgn0053388.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33388 CR33388 16-Dec-15 2015_12 FBgn0038901 Burs Bursicon http://flybase.net/reports/FBgn0038901.html protein_coding_gene "0071855=neuropeptide receptor binding, 0005179=hormone activity, 0005184=neuropeptide hormone activity" "0048082=regulation of adult chitin-containing cuticle pigmentation, 0007593=chitin-based cuticle sclerotization, 0007564=regulation of chitin-based cuticle tanning, 0048067=cuticle pigmentation, 0007476=imaginal disc-derived wing morphogenesis" "0043195=terminal bouton, 0005576=extracellular region, 0031395=bursicon neuropeptide hormone complex" "unnamed, frl, Bursicon alpha subunit, furled wing, burs, BURS, Bur alpha, burs alpha, Bursicon, bursicon, bursalpha, CG13419, bursicon alpha, burs-alpha, bursicon alpha-subunit, Burs alpha, Bursalpha" "IPR004133=DAN, IPR006207=Cystine knot, C-terminal" CG13419 16-Dec-15 2015_12 "viable,visible,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,adult cuticle,adult abdomen,posterior scutellar bristle,adult thorax" FBgn0263086 CG43354 http://flybase.net/reports/FBgn0263086.html protein_coding_gene lincRNA.182 CG43354 16-Dec-15 2015_12 FBgn0003989 vr varnished http://flybase.net/reports/FBgn0003989.html gene 16-Dec-15 2015_12 female sterile "eye,ommatidium" FBgn0267958 CR46238 http://flybase.net/reports/FBgn0267958.html non_protein_coding_gene lincRNA.760 CR46238 16-Dec-15 2015_12 FBgn0011077 l(1)Q31 lethal (1) Q31 http://flybase.net/reports/FBgn0011077.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0028887 CG3491 http://flybase.net/reports/FBgn0028887.html protein_coding_gene 0003677=DNA binding "0006355=regulation of transcription, DNA-templated" BG:DS03323.1 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR026937=Strawberry notch, helicase C domain, IPR026741=Protein strawberry notch, IPR017956=AT hook, DNA-binding motif" CG3491 16-Dec-15 2015_12 ENSDARG00000003882(sbno2a) ENSXETG00000021579(SBNO2) viable FBgn0262000 CG42818 http://flybase.net/reports/FBgn0262000.html "FBgn0028859, FBan0012455, FBgn0032581, FBgn0044794" protein_coding_gene "DS07473.1A, BG:DS07473.1, CG12455" CG42818 16-Dec-15 2015_12 FBgn0263556 mir-4940 mir-4940 stem loop http://flybase.net/reports/FBgn0263556.html miRNA_gene "CR43541, dme-mir-4940" CR43541 16-Dec-15 2015_12 FBgn0028647 CG11902 http://flybase.net/reports/FBgn0028647.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "unnamed, anon-96CDa" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG11902 16-Dec-15 2015_12 viable FBgn0001157 gustE gustatory-defective E http://flybase.net/reports/FBgn0001157.html gene 16-Dec-15 2015_12 "taste perception defective,recessive" taste bristle FBgn0060666 l(3)S080503 lethal (3) S080503 http://flybase.net/reports/FBgn0060666.html gene 0805/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0265365 CR44306 http://flybase.net/reports/FBgn0265365.html non_protein_coding_gene CR44306 16-Dec-15 2015_12 FBgn0065644 l(2)SH0753 lethal (2) SH0753 http://flybase.net/reports/FBgn0065644.html gene l(2)SH2 0753 16-Dec-15 2015_12 "lethal,recessive" FBgn0010112 fs(1)de4 female sterile (1) defective eggs 4 http://flybase.net/reports/FBgn0010112.html gene de4 16-Dec-15 2015_12 female sterile "endochorion,dorsal appendage,chorion" FBgn0035333 CG1317 http://flybase.net/reports/FBgn0035333.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0030176=integral component of endoplasmic reticulum membrane "IPR011016=Zinc finger, RING-CH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG1317 16-Dec-15 2015_12 WBGene00018847(marc-6) ENSXETG00000003553(MARCH6) ENSMUSG00000039100(March6) ENSG00000145495(MARCH6) "viable,fertile" FBgn0265634 CR44441 http://flybase.net/reports/FBgn0265634.html non_protein_coding_gene lincRNA.S8353 CR44441 16-Dec-15 2015_12 FBgn0002415 l(3)DTS2 lethal (3) DTS2 http://flybase.net/reports/FBgn0002415.html gene DTS-2 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039938 Sox102F Sox102F http://flybase.net/reports/FBgn0039938.html FBgn0043567 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0045823=positive regulation of heart contraction, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Sox D, SOX102D, Sox102D, CG11153, SoxD, SOXD" IPR009071=High mobility group box domain CG11153 16-Dec-15 2015_12 "ENSDARG00000011582(sox5),ENSDARG00000015536(sox6),ENSDARG00000030297" "ENSXETG00000016058(SOX6),ENSXETG00000017139(TGas067m20.1)" "ENSMUSG00000051910(Sox6),ENSMUSG00000041540(Sox5),ENSMUSG00000070643(Sox13)" "ENSG00000134532(SOX5),ENSG00000110693(SOX6),ENSG00000143842(SOX13)" "visible,viable" "adult heart,myofibrilhow-24B,wing,wing vein L2,wing vein L3,ectopic,eye" FBgn0013245 E(var)27 E(var)27 http://flybase.net/reports/FBgn0013245.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0000185 bie bientot http://flybase.net/reports/FBgn0000185.html gene beintot 16-Dec-15 2015_12 "female sterile,recessive,visible,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,maternal effect" "stage 5 embryo,embryonic/first instar larval cuticle,tergite" FBgn0032899 CG9338 http://flybase.net/reports/FBgn0032899.html FBgn0063264 protein_coding_gene BcDNA:GH07967 CG9338 16-Dec-15 2015_12 viable DRSC24503 K -0.326292227 0.258428317 -0.185042133 -0.249631514 -0.100595605 -1.67004944 FBgn0263627 CR43636 http://flybase.net/reports/FBgn0263627.html non_protein_coding_gene CR43636 16-Dec-15 2015_12 FBgn0000211 bra breakage during anaphase http://flybase.net/reports/FBgn0000211.html gene 16-Dec-15 2015_12 mitotic cell cycle defective FBgn0002915 mc-44A mc-44A http://flybase.net/reports/FBgn0002915.html gene "Myc oncogene, Dmmyc, Myc, Dmc" 16-Dec-15 2015_12 FBgn0032894 CG14402 http://flybase.net/reports/FBgn0032894.html FBgn0063750 protein_coding_gene BcDNA:AT08210 CG14402 16-Dec-15 2015_12 viable DRSC02386 I 1.739232661 -0.122428543 0.540751925 -0.371056164 0.056215841 0.608063791 FBgn0082968 snoRNA:ë¬28S-3316e snoRNA:ë¬28S-3316e http://flybase.net/reports/FBgn0082968.html snoRNA_gene "CR34554, Psi28S-3316e, psi28S-3316e" CR34554 16-Dec-15 2015_12 FBgn0010793 l(3)03077 lethal (3) 03077 http://flybase.net/reports/FBgn0010793.html gene 16-Dec-15 2015_12 lethal FBgn0011090 l(1)Q50 lethal (1) Q50 http://flybase.net/reports/FBgn0011090.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0267269 CR45705 http://flybase.net/reports/FBgn0267269.html non_protein_coding_gene CR45705 16-Dec-15 2015_12 FBgn0051673 CG31673 http://flybase.net/reports/FBgn0051673.html "FBgn0032890, FBgn0063161" protein_coding_gene "0051287=NAD binding, 0030267=glyoxylate reductase (NADP) activity" 0055114=oxidation-reduction process "BcDNA:LD14730, CCG31673, CG9332" "IPR006140=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040=NAD(P)-binding domain, IPR029753=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site, IPR006139=D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain" CG31673 16-Dec-15 2015_12 YNL274C(GOR1) viable FBgn0001464 l(1)7Ee lethal (1) 7Ee http://flybase.net/reports/FBgn0001464.html gene 16-Dec-15 2015_12 lethal FBgn0260569 MENE-MM15 http://flybase.net/reports/FBgn0260569.html gene 16-Dec-15 2015_12 "hyperplasia,somatic clone" "eye disc,somatic clone" FBgn0005310 ms(1)RD33 male sterile (1) RD33 http://flybase.net/reports/FBgn0005310.html gene 16-Dec-15 2015_12 male sterile "spermatocyte,spermatid" FBgn0083065 rpn rantanplan http://flybase.net/reports/FBgn0083065.html gene 16-Dec-15 2015_12 FBgn0070005 BG01526 BG01526 http://flybase.net/reports/FBgn0070005.html gene 16-Dec-15 2015_12 stress response defective FBgn0260088 2L0028 http://flybase.net/reports/FBgn0260088.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0002545 lf little fly http://flybase.net/reports/FBgn0002545.html gene "9, section 9, 12, l152, lT2-14a, l(1)19Ee, section 12, lN5" 16-Dec-15 2015_12 "viable,reduced,fertile,visible,lethal,recessive" adult abdomen FBgn0046650 anon-38D.15 anon-38D.15 http://flybase.net/reports/FBgn0046650.html gene 38D.15 16-Dec-15 2015_12 FBgn0005031 E(M99E) Enhancer of Minute(3)99E http://flybase.net/reports/FBgn0005031.html gene E(M3g) 16-Dec-15 2015_12 FBgn0259344 C478 http://flybase.net/reports/FBgn0259344.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0051427 CG31427 http://flybase.net/reports/FBgn0051427.html FBgn0039657 protein_coding_gene "0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis CG11955 "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase" CG31427 16-Dec-15 2015_12 DRSC22675 K -0.077291304 0.39392392 -0.016155036 0.298486407 1.87596726 -0.184063301 FBgn0013700 mt:tRNA:M mitochondrial methionine tRNA http://flybase.net/reports/FBgn0013700.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "tRNA-Met, mtdbD00006294, tRNA[f-met], tRNA[Met], CR34062" CR34062 16-Dec-15 2015_12 FBgn0003558 Su(er) Suppressor of erupt http://flybase.net/reports/FBgn0003558.html gene 16-Dec-15 2015_12 FBgn0060550 l(3)S098502 lethal (3) S098502 http://flybase.net/reports/FBgn0060550.html gene 0985/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0266242 CR44937 http://flybase.net/reports/FBgn0266242.html non_protein_coding_gene lincRNA.733 CR44937 16-Dec-15 2015_12 FBgn0031893 CG4495 http://flybase.net/reports/FBgn0031893.html protein_coding_gene 0005509=calcium ion binding 0051561=positive regulation of mitochondrial calcium ion concentration "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG4495 16-Dec-15 2015_12 ENSDARG00000063358(zgc:162148) WBGene00013462(Y67H2A.4) ENSMUSG00000020111(Cbara1) ENSG00000107745(MICU1) "partially lethal - majority die,some die during pupal stage" DRSC02752 K 0.112096133 -0.310052943 -0.312297822 -0.507856105 1.961459342 -1.07381608 FBgn0011111 l(1)Q72 lethal (1) Q72 http://flybase.net/reports/FBgn0011111.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0085241 CG34212 http://flybase.net/reports/FBgn0085241.html protein_coding_gene CG34212 16-Dec-15 2015_12 FBgn0085689 CG41558 http://flybase.net/reports/FBgn0085689.html FBan0041558 protein_coding_gene 16-Dec-15 2015_12 FBgn0086207 E(ls)3 http://flybase.net/reports/FBgn0086207.html gene 16-Dec-15 2015_12 FBgn0010240 Lcch3 Ligand-gated chloride channel homolog 3 http://flybase.net/reports/FBgn0010240.html protein_coding_gene "0004890=GABA-A receptor activity, 0005230=extracellular ligand-gated ion channel activity" 0006811=ion transport "0005886=plasma membrane, 0016021=integral component of membrane" "GABA receptor beta subunit, DmGABAbeta, ligand-gated chloride channel, DmGA_b, CG17336, ligand-gated chloride channel homologue 3, LCCH3, beta subunit, CT38330" "IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR002289=Gamma-aminobutyric-acid A receptor, beta subunit, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006201=Neurotransmitter-gated ion-channel" CG17336 16-Dec-15 2015_12 "ENSDARG00000023771(LOC566922),ENSDARG00000018935" WBGene00001512(gab-1) "ENSXETG00000011917(GABRB2),ENSXETG00000009630(),ENSXETG00000024288(GABRB3)" "ENSMUSG00000033676(Gabrb3),ENSMUSG00000007653(Gabrb2),ENSMUSG00000029212(Gabrb1)" "ENSG00000163288(GABRB1),ENSG00000145864(GABRB2),ENSG00000166206(GABRB3)" viable FBgn0035789 mthl6 methuselah-like 6 http://flybase.net/reports/FBgn0035789.html "FBgn0046603, FBgn0046604" protein_coding_gene 0004930=G-protein coupled receptor activity "0042594=response to starvation, 0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan" 0016021=integral component of membrane "CG16992, anon-WO0170980.128, Mth-like 6, anon-WO0170980.127, mth-like 6" "IPR017981=GPCR, family 2-like, IPR023311=Methuselah ectodomain, domain 2, IPR010596=Methuselah, N-terminal domain, IPR022343=GCR1-cAMP receptor, IPR000832=GPCR, family 2, secretin-like" CG16992 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" viable FBgn0263561 mir-4984 mir-4984 stem loop http://flybase.net/reports/FBgn0263561.html miRNA_gene "CR43546, dme-mir-4984" CR43546 16-Dec-15 2015_12 FBgn0051266 CG31266 http://flybase.net/reports/FBgn0051266.html FBgn0038483 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG5240, SPH146" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan" CG31266 16-Dec-15 2015_12 viable FBgn0028018 l(3)S104913b lethal (3) S104913b http://flybase.net/reports/FBgn0028018.html gene "1049/13, l(3)S104913" 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" FBgn0036848 CG10424 http://flybase.net/reports/FBgn0036848.html protein_coding_gene 0052855=ADP-dependent NAD(P)H-hydrate dehydratase activity "IPR000631=ATP-dependent (S)-NAD(P)H-hydrate dehydratase, IPR017953=Carbohydrate kinase, predicted, conserved site, IPR029056=Ribokinase-like" CG10424 16-Dec-15 2015_12 YKL151C() WBGene00011298(R107.2) ENSXETG00000008207(CARKD) ENSMUSG00000031505(Carkd) ENSG00000213995(CARKD) "viable,fertile" FBgn0259720 CG42374 http://flybase.net/reports/FBgn0259720.html protein_coding_gene Dromel_CG9666_FBtr0074991_uORF CG42374 16-Dec-15 2015_12 ENSDARG00000028523(zgc:56259) ENSG00000148153(C9orf80) FBgn0027500 spd-2 spindle defective 2 http://flybase.net/reports/FBgn0027500.html FBgn0014928 protein_coding_gene "0007052=mitotic spindle organization, 0030953=astral microtubule organization, 0090307=mitotic spindle assembly, 0035044=sperm aster formation, 0051297=centrosome organization" "0005814=centriole, 0000242=pericentriolar material, 0005813=centrosome" "SPD2, Cep192, DSpd2, CG17286-PA, anon-73Ba, unnamed, Spd2, DSpd-2, D-Spd2, D-SPD2, dSpd2, Dspd-2, SPD-2, Dspd2, Spd-2, CG17286, CEP192, spd2, BcDNA:LD24702, DSPD-2" CG17286 16-Dec-15 2015_12 "lethal,maternal effect,male sterile,viable,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage,female sterile,uncoordinated" "centriole | ectopic,spermatocyte,onion stage spermatid,aster,spermatid,spermatozoon,asterst-j7),centrosomest-j7),primary spermatocyte" FBgn0001045 fs(3)HO127 female sterile (3) HO127 http://flybase.net/reports/FBgn0001045.html gene fs(3)127A 16-Dec-15 2015_12 female sterile oocyte FBgn0031130 CG15452 http://flybase.net/reports/FBgn0031130.html protein_coding_gene CG15452 16-Dec-15 2015_12 "viable,fertile" FBgn0065304 l(2)SH1975 lethal (2) SH1975 http://flybase.net/reports/FBgn0065304.html gene l(2)SH2 1975 16-Dec-15 2015_12 "lethal,recessive" FBgn0065094 snmRNA:419 small non-messenger RNA 419 http://flybase.net/reports/FBgn0065094.html FBgn0053917 non_protein_coding_gene "Dm-419, CR33917" CR33917 16-Dec-15 2015_12 FBgn0032450 CG5776 http://flybase.net/reports/FBgn0032450.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" 0005783=endoplasmic reticulum "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain" CG5776 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0042650 disco-r disco-related http://flybase.net/reports/FBgn0042650.html "FBgn0030727, FBgn0030728, FBgn0052577, FBgn0063604" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG32577, CG9223, CG9219, disconnected-related, disco-r" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG32577 16-Dec-15 2015_12 ENSDARG00000069989(bnc2) "viable,visible" "antenna,leg,ectopic" FBgn0035228 CG12091 http://flybase.net/reports/FBgn0035228.html protein_coding_gene "0004721=phosphoprotein phosphatase activity, 0004722=protein serine/threonine phosphatase activity" 0006470=protein dephosphorylation 0005739=mitochondrion IPR001932=PPM-type phosphatase domain CG12091 16-Dec-15 2015_12 "ENSDARG00000052658(si:ch211-193e13.3),ENSDARG00000011122(pptc7)" YHR076W(PTC7) WBGene00012362(W09D10.4) ENSXETG00000020935(PPTC7) ENSMUSG00000038582(Pptc7) ENSG00000196850(PPTC7) viable FBgn0028894 GMF Glia maturation factor http://flybase.net/reports/FBgn0028894.html FBgn0062894 protein_coding_gene "0071933=Arp2/3 complex binding, 0003779=actin binding" "0034316=negative regulation of Arp2/3 complex-mediated actin nucleation, 0007298=border follicle cell migration, 0031344=regulation of cell projection organization, 0071846=actin filament debranching, 0042063=gliogenesis, 0030833=regulation of actin filament polymerization" "0071944=cell periphery, 0030027=lamellipodium, 0048471=perinuclear region of cytoplasm, 0005634=nucleus" "glia-maturation factor, gmf, CG5869, BcDNA:SD03793, BG:DS02740.9, dGMF, DS02740.9" "IPR002108=Actin-depolymerising factor homology domain, IPR029006=ADF-H/Gelsolin-like domain, IPR011171=Glia maturation factor" CG5869 16-Dec-15 2015_12 ENSDARG00000028327(gmfb) WBGene00021758(Y50D7A.10) ENSXETG00000012224(gmfb) "ENSMUSG00000060791(Gmfg),ENSMUSG00000062014(Gmfb)" "ENSG00000197045(GMFB),ENSG00000130755(GMFG)" viable FBgn0005480 l(1)ts1137 lethal (1) ts1137 http://flybase.net/reports/FBgn0005480.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0028663 VhaM9.7-b Vacuolar H+ ATPase M9.7 subunit b http://flybase.net/reports/FBgn0028663.html "FBgn0037096, FBgn0061891" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0015078=hydrogen ion transmembrane transporter activity" 0015991=ATP hydrolysis coupled proton transport "0033181=plasma membrane proton-transporting V-type ATPase complex, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "vhaM9.2-2, Vacuolar H[+] ATPase subunit M9.7-b, VhaM9.7-2, Vha M9.7-2, anon-WO0118547.551, vhaM9.7-b, CG7625, ATP6V0M9.7-2, vhaM9.7-2" "IPR008389=ATPase, V0 complex, subunit e1/e2, IPR017385=ATPase, V0 complex, subunit e1/e2, metazoa" CG7625 16-Dec-15 2015_12 "ENSDARG00000059057(zgc:109987),ENSDARG00000039642(zgc:103433)" WBGene00009882(vha-17) ENSXETG00000024781(ATP6V0E1) "ENSMUSG00000039347(Atp6v0e2),ENSMUSG00000015575(Atp6v0e)" ENSG00000113732(ATP6V0E1) "lethal - all die before end of embryonic stage,some die during embryonic stage,body color defective,partially lethal - majority die,some die during pupal stage" "Malpighian tubule,mesothoracic tergum" FBgn0053120 CG33120 http://flybase.net/reports/FBgn0053120.html FBgn0032718 protein_coding_gene 0004144=diacylglycerol O-acyltransferase activity CG10599 "IPR009721=O-acyltransferase WSD1, C-terminal" CG33120 16-Dec-15 2015_12 viable FBgn0042094 Adk3 Adenylate kinase 3 http://flybase.net/reports/FBgn0042094.html FBgn0037854 protein_coding_gene "0046899=nucleoside triphosphate adenylate kinase activity, 0005524=ATP binding, 0004017=adenylate kinase activity" 0006172=ADP biosynthetic process "0005759=mitochondrial matrix, 0005739=mitochondrion" "Dak3, ADENYLATE KINASE - 3, Adenylate kinase-3, bs12h03.y1, CG6612, AK3, DAK3" "IPR028586=Adenylate kinase 3/4, mitochondrial, IPR007862=Adenylate kinase, active site lid domain, IPR000850=Adenylate kinase/UMP-CMP kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006259=Adenylate kinase subfamily" CG6612 16-Dec-15 2015_12 "ENSDARG00000058226(ak3),ENSDARG00000006546(ak4)" YER170W(ADK2) WBGene00014058(ZK673.2) "ENSXETG00000000588(AK3),ENSXETG00000020392(AK3L1)" "ENSMUSG00000024782(Ak3),ENSMUSG00000028527(Ak4)" "ENSG00000147853(AK3),ENSG00000162433(AK4)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC16075 K -0.061362466 -0.066519469 0.642398619 0.525573035 1.125668306 2.045279065 FBgn0013987 MAPk-Ak2 MAP kinase activated protein-kinase-2 http://flybase.net/reports/FBgn0013987.html FBgn0029802 protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0045793=positive regulation of cell size, 0007155=cell adhesion, 0046328=regulation of JNK cascade, 0008360=regulation of cell shape, 0009651=response to salt stress, 0006468=protein phosphorylation" "0005737=cytoplasm, 0005634=nucleus" "MAPKAP, dMK2, MAP kinase activated protein kinase-2, CG3086, MK2, MAPKAPK-2, DmMAPKAPK-2" "IPR011009=Protein kinase-like domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR027442=MAP kinase activated protein kinase, C-terminal domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG3086 16-Dec-15 2015_12 "ENSDARG00000002552(mapkapk2a),ENSDARG00000055745,ENSDARG00000018530(mapkapk2b)" WBGene00007007(mak-2) "ENSXETG00000023673(mapkapk2),ENSXETG00000000076(MAPKAPK3)" "ENSMUSG00000016528(Mapkapk2),ENSMUSG00000032577(Mapkapk3)" "ENSG00000162889(MAPKAPK2),ENSG00000114738(MAPKAPK3)" " embryonic stage -- adult stage , oogenesis stage && adult stage | female , embryonic stage | early " ovary

"viable,partially lethal - majority live,nutrition conditional,melanotic mass phenotype" "embryonic/larval hindgut,posterior,nutrition conditional" FBgn0019698 l(2)k03111 lethal (2) k03111 http://flybase.net/reports/FBgn0019698.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002045 l(2)37Di lethal (2) 37Di http://flybase.net/reports/FBgn0002045.html gene "E103, l(2)E103" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051021 CG31021 http://flybase.net/reports/FBgn0051021.html FBgn0039791 protein_coding_gene "0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum CG9708 "IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990=Tetratricopeptide-like helical domain" CG31021 16-Dec-15 2015_12 viable FBgn0029154 Menl-1 Malic enzyme like-1 http://flybase.net/reports/FBgn0029154.html "FBgn0034124, FBgn0050097, FBtr0087161, FBpp0086305, FBtr0087162, FBpp0086306, FBtr0087163, FBpp0086307, FBtr0087164, FBpp0086308, FBtr0087165, FBpp0086309, FBtr0087166, FBpp0086310" protein_coding_gene "0004473=malate dehydrogenase (decarboxylating) (NADP+) activity, 0051287=NAD binding, 0004471=malate dehydrogenase (decarboxylating) (NAD+) activity" "0006108=malate metabolic process, 0055114=oxidation-reduction process" 0005739=mitochondrion "CG7964, CG30097, Menl-1" "IPR015884=Malic enzyme, conserved site, IPR016040=NAD(P)-binding domain, IPR001891=Malic oxidoreductase, IPR012302=Malic enzyme, NAD-binding, IPR012301=Malic enzyme, N-terminal domain" CG7964 16-Dec-15 2015_12 YKL029C(MAE1) DRSC07470 I 1.812401681 0.496558877 0.116615905 -0.227669372 0.531992361 -1.302536282 FBgn0010831 l(3)04063 lethal (3) 04063 http://flybase.net/reports/FBgn0010831.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020842 l(2)BV "Blacksburg, VA" http://flybase.net/reports/FBgn0020842.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035666 Jon65Aii Jonah 65Aii http://flybase.net/reports/FBgn0035666.html FBgn0001286 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "Jon65A, CG6580, Jonah 65A, SP153" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG6580 16-Dec-15 2015_12 viable FBgn0028408 Drep2 DNA fragmentation factor-related protein 2 http://flybase.net/reports/FBgn0028408.html "FBgn0062196, FBgn0062202" protein_coding_gene 0004518=nuclease activity "0022008=neurogenesis, 0006915=apoptotic process, 1901215=negative regulation of neuron death" "0097060=synaptic membrane, 0045211=postsynaptic membrane, 0005622=intracellular" "Drep2, rep2, Drep-2, Rep2, CG1975, anon-WO0118547.168, anon-WO0118547.162, drep2, DREP-2" IPR003508=CIDE-N domain CG1975 16-Dec-15 2015_12 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0262417 mir-316 mir-316 stem loop http://flybase.net/reports/FBgn0262417.html "FBgn0067688, FBgn0262258" miRNA_gene "CR33620, dme-mir-316, dme-miR-316, miR-316, mir-316, Mir-316, CR42965" CR42965 16-Dec-15 2015_12 "visible,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin,wing vein" FBgn0001501 l(1)10Cd lethal (1) 10Cd http://flybase.net/reports/FBgn0001501.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033308 CG8736 http://flybase.net/reports/FBgn0033308.html FBgn0062966 protein_coding_gene BcDNA:RH08259 CG8736 16-Dec-15 2015_12 viable FBgn0027338 Kap-ë±3 karyopherin ë±3 http://flybase.net/reports/FBgn0027338.html "FBgn0024888, FBgn0026235, FBgn0028164" protein_coding_gene "0017022=myosin binding, 0008320=protein transmembrane transporter activity, 0008565=protein transporter activity" "0007095=mitotic G2 DNA damage checkpoint, 0051533=positive regulation of NFAT protein import into nucleus, 0009411=response to UV, 0006606=protein import into nucleus" "0005737=cytoplasm, 0005643=nuclear pore" "karyopherin a3, dImportin-alpha3, Imp alpha-3, kpn-alpha3, Importin alpha3, importin a3, Karyopherin alpha3, importin alpha, dimpalpha3, importin alpha3, Kap-?3, Importin alpha-3, Kpna3, imp alpha3, karyopherin-alpha4, KAP-ALPHA3, imp-alpha3, IMPalpha3, importin-alpha3, imp-a3, importin alpha-3, impalpha3, karyopherin alpha3, CG9423, Importin-alpha3, karyopherin alpha4, 0335/13, Kap-alpha3, Kapalpha3, dKap-alpha3, l(3)S033513, Imp-alpha3, Kap alpha3, alphaKap3, Dalpha3, karyopherin-alpha3" "IPR002652=Importin-alpha, importin-beta-binding domain, IPR011989=Armadillo-like helical, IPR024931=Importin subunit alpha, IPR016024=Armadillo-type fold, IPR000225=Armadillo" CG9423 16-Dec-15 2015_12 "ENSDARG00000023190(kpna4),ENSDARG00000052641(kpna3)" WBGene00002074(ima-3) "ENSXETG00000008720(KPNA4),ENSXETG00000015677(KPNA3)" "ENSMUSG00000021929(Kpna3),ENSMUSG00000027782(Kpna4)" "ENSG00000102753(KPNA3),ENSG00000186432(KPNA4)" embryonic stage -- adult stage "viable,fertile,lethal,female,lethal - all die before end of larval stage,some die during larval stage,wild-type,phototaxis defective,somatic clone,visible,heat sensitive,partially lethal - majority die,neuroanatomy defective" "eye,somatic clone,ommatidium,interommatidial bristle,rhabdomere,photoreceptor cell R7,tormogen cell,tergite,mesothoracic tergum" FBgn0085294 CG34265 http://flybase.net/reports/FBgn0085294.html protein_coding_gene CG34265 16-Dec-15 2015_12 FBgn0000070 Alu Alula http://flybase.net/reports/FBgn0000070.html gene 16-Dec-15 2015_12 "visible,dominant,viable" "alula,wing" FBgn0004228 mex1 midgut expression 1 http://flybase.net/reports/FBgn0004228.html protein_coding_gene 0022900=electron transport chain 0016021=integral component of membrane "CG7936, Midgut expression 1" "IPR011759=Cytochrome C oxidase subunit II, transmembrane domain" CG7936 16-Dec-15 2015_12 " embryonic stage | stage 12 , embryonic stage | stage >=12 , embryonic stage | stage >=9 , embryonic stage | stage >=14 , adult stage " " anterior midgut proper primordium

, posterior midgut proper primordium

, embryonic/larval midgut

" "viable,fertile" FBgn0013495 l(1)HA6 lethal (1) HA6 http://flybase.net/reports/FBgn0013495.html gene HA6 16-Dec-15 2015_12 lethal FBgn0010414 SerT Serotonin transporter http://flybase.net/reports/FBgn0010414.html FBgn0011835 protein_coding_gene "0005261=cation channel activity, 0008504=monoamine transmembrane transporter activity, 0015222=serotonin transmembrane transporter activity, 0005328=neurotransmitter:sodium symporter activity" "0006837=serotonin transport, 0006909=phagocytosis, 0051610=serotonin uptake, 0015844=monoamine transport" "0005887=integral component of plasma membrane, 0030424=axon, 0005886=plasma membrane, 0016021=integral component of membrane, 0043679=axon terminus" "dSERT1, dSert, Sert, dSerT, DmSerT, dSERT, CG4545, dsert, serT, SERT, cocaine-sensitive serotonin transporter, Drosophila Serotonin transporter, DmSERT, Drosophila serotonin transporter, serotonin transporter" IPR000175=Sodium:neurotransmitter symporter CG4545 16-Dec-15 2015_12 "ENSDARG00000057017(slc6a4b),ENSDARG00000061165(slc6a4a)" WBGene00003387(mod-5) ENSXETG00000018650() ENSMUSG00000020838(Slc6a4) ENSG00000108576(SLC6A4) " larval stage , adult stage , embryonic stage | stage 15-17 " " larval central nervous system | restricted

, adult head

, embryonic central nervous system | restricted

" viable DRSC04655 I 0.893348037 -2.124372974 0.535584996 0.760108681 0.314793031 0.662334174 FBgn0038690 CG11703 http://flybase.net/reports/FBgn0038690.html FBgn0044581 protein_coding_gene 0005391=sodium:potassium-exchanging ATPase activity "0006814=sodium ion transport, 0006813=potassium ion transport" "0005886=plasma membrane, 0005890=sodium:potassium-exchanging ATPase complex" "JYbeta2, anon-WO0140519.49" IPR000402=Sodium/potassium-transporting ATPase subunit beta CG11703 16-Dec-15 2015_12 viable FBgn0000688 flrdL flight reduced L http://flybase.net/reports/FBgn0000688.html gene 0007629=flight behavior 16-Dec-15 2015_12 "hypoactive,flight defective" FBgn0062694 EP1236 EP1236 http://flybase.net/reports/FBgn0062694.html gene EP(2)1236 16-Dec-15 2015_12 FBgn0262606 CR43132 http://flybase.net/reports/FBgn0262606.html non_protein_coding_gene "mdcds_55191, lincRNA.1005, CG43132" CR43132 16-Dec-15 2015_12 FBgn0065433 l(2)SH1482 lethal (2) SH1482 http://flybase.net/reports/FBgn0065433.html gene l(2)SH2 1482 16-Dec-15 2015_12 "lethal,recessive" FBgn0001438 l(1)7Bf lethal (1) 7Bf http://flybase.net/reports/FBgn0001438.html gene l(1)GF320 16-Dec-15 2015_12 lethal FBgn0004367 mei-41 meiotic 41 http://flybase.net/reports/FBgn0004367.html "FBgn0002708, FBgn0002880" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0016301=kinase activity" "0008360=regulation of cell shape, 0007095=mitotic G2 DNA damage checkpoint, 0016310=phosphorylation, 0007131=reciprocal meiotic recombination, 0018105=peptidyl-serine phosphorylation, 0007088=regulation of mitotic nuclear division, 0045003=double-strand break repair via synthesis-dependent strand annealing, 0006974=cellular response to DNA damage stimulus, 0000077=DNA damage checkpoint, 0007093=mitotic cell cycle checkpoint, 0045002=double-strand break repair via single-strand annealing, 0007015=actin filament organization, 0009314=response to radiation, 0006468=protein phosphorylation, 0000723=telomere maintenance, 0016321=female meiosis chromosome segregation, 0000076=DNA replication checkpoint, 0048477=oogenesis, 0000706=meiotic DNA double-strand break processing, 0007348=regulation of syncytial blastoderm mitotic cell cycle, 0007444=imaginal disc development, 0030261=chromosome condensation, 0031000=response to caffeine, 0001700=embryonic development via the syncytial blastoderm, 0007126=meiotic nuclear division, 0033314=mitotic DNA replication checkpoint, 0007349=cellularization" 0005634=nucleus "mei41, fs(1)M37, 4252, DmATR, mus-103, Meiotic 41, atr, mei-195, Mei-41/DATR, MEI41, meiP41, CG4252, Mei-41, meiotic-41, ATR, mus(1)103, Drosophila ATR, mus(1)104, mus-104, mus103, MEI41/FRP1, Dmmei41, mus104, ATM-RAD3 related" "IPR014009=PIK-related kinase, IPR011990=Tetratricopeptide-like helical domain, IPR003152=FATC domain, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR011009=Protein kinase-like domain, IPR016024=Armadillo-type fold, IPR003151=PIK-related kinase, FAT, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR012993=UME" CG4252 16-Dec-15 2015_12 ENSDARG00000002385 YBR136W(MEC1) ENSXETG00000000617(ATR) ENSMUSG00000032409 ENSG00000175054(ATR) oogenesis stage && adult stage | female ovary

"female sterile,partially,chemical sensitive,viable,semidominant,heat sensitive,recessive,radiation sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,female fertile,wild-type,lethal,rescuable maternal effect,female semi-sterile,maternal effect,DNA repair defective,dominant,mitotic cell cycle defective,radiation resistant,reduced,decreased cell death,increased cell death" "egg,maternal effect,mitotic interphase | embryonic cycle 12 | maternal effect,mitotic interphase | embryonic cycle 13 | maternal effect,blastoderm embryo,cycle 13 embryo,cycle 14 embryo,spindle,neuroblast,presumptive oocyte,mitosis & nuclear chromosome,eye disc,conditional,morphogenetic furrow,metaphase & condensed nuclear chromosome | conditional qualifier,wing disc,SO0000340chromosome | larval stage" FBgn0065102 snmRNA:184 small non-messenger RNA 184 http://flybase.net/reports/FBgn0065102.html FBgn0053916 non_protein_coding_gene "Dm-184, CR33916" CR33916 16-Dec-15 2015_12 FBgn0011007 l(3)s1696 lethal (3) s1696 http://flybase.net/reports/FBgn0011007.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0037723 SpdS Spermidine Synthase http://flybase.net/reports/FBgn0037723.html protein_coding_gene 0004766=spermidine synthase activity 0008295=spermidine biosynthetic process "CG8327, Spds" "IPR030374=Polyamine biosynthesis domain, IPR030373=Polyamine biosynthesis domain, conserved site, IPR001045=Spermidine/spermine synthases, IPR030668=Spermidine/spermine synthase, eukaryotes, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG8327 16-Dec-15 2015_12 ENSDARG00000055760(zgc:63600) "YPR069C(SPE3),YLR146C(SPE4)" WBGene00012909(Y46G5A.19) ENSXETG00000028025(SRM) ENSMUSG00000006442(Srm) ENSG00000116649(SRM) "long lived,viable" FBgn0058412 CG40412 http://flybase.net/reports/FBgn0058412.html protein_coding_gene 16-Dec-15 2015_12 FBgn0082981 snoRNA:ë¬28S-2949 snoRNA:ë¬28S-2949 http://flybase.net/reports/FBgn0082981.html snoRNA_gene "CR34525, Psi28S-2949, Psi 28S-2949, psi28S-2949" CR34525 16-Dec-15 2015_12 FBgn0032648 CG15144 http://flybase.net/reports/FBgn0032648.html protein_coding_gene IPR026720=Protein MAATS1 CG15144 16-Dec-15 2015_12 ENSDARG00000006292(si:dkey-265i7.2) ENSXETG00000018054(C3orf15) ENSMUSG00000022805(4932425I24Rik) ENSG00000183833(C3orf15) viable FBgn0267257 CR45693 http://flybase.net/reports/FBgn0267257.html non_protein_coding_gene CR45693 16-Dec-15 2015_12 FBgn0259388 C545 http://flybase.net/reports/FBgn0259388.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0004507 GlyP Glycogen phosphorylase http://flybase.net/reports/FBgn0004507.html "FBgn0027859, FBgn0063790" protein_coding_gene "0042803=protein homodimerization activity, 0008184=glycogen phosphorylase activity, 0030170=pyridoxal phosphate binding" "0005980=glycogen catabolic process, 0060361=flight, 0045824=negative regulation of innate immune response, 0045819=positive regulation of glycogen catabolic process, 0050829=defense response to Gram-negative bacterium, 0008340=determination of adult lifespan" 0043234=protein complex "Glp1, glycogen phosphorylase b, l(2)k07918, CG7254, BcDNA:LD24485, DGPH, glycogen phosphorylase, Glyp, GP, anon-WO0257455.33" "IPR011833=Glycogen/starch/alpha-glucan phosphorylase, IPR000811=Glycosyl transferase, family 35" CG7254 16-Dec-15 2015_12 "ENSDARG00000055518(pygma),ENSDARG00000013317(pygmb),ENSDARG00000002021(pygb)" YPR160W(GPH1) WBGene00020696(T22F3.3) "ENSXETG00000016477(PYGL),ENSXETG00000012788(pygb)" "ENSMUSG00000032648(Pygm),ENSMUSG00000033059(Pygb),ENSMUSG00000021069(Pygl)" "ENSG00000068976(PYGM),ENSG00000100994(PYGB),ENSG00000100504(PYGL)" " embryonic stage | 0-2hr , embryonic stage -- adult stage " "long lived,RU486 conditional,viable,reduced" FBgn0060824 l(3)S051701b lethal (3) S051701b http://flybase.net/reports/FBgn0060824.html gene 0517/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0004411 het-rep3 heterochromatic repeat 3 http://flybase.net/reports/FBgn0004411.html repeat_region 16-Dec-15 2015_12 FBgn0051296 CG31296 http://flybase.net/reports/FBgn0051296.html FBgn0045440 protein_coding_gene 0005576=extracellular region NEST:bs01d08 "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG31296 16-Dec-15 2015_12 "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" viable FBgn0004061 bip bipolar oocyte http://flybase.net/reports/FBgn0004061.html gene "0048477=oogenesis, 0007314=oocyte anterior/posterior axis specification" BiP 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,egg chamber,nurse cell,stage S14B oocyte,oocyte" FBgn0002555 lm limited http://flybase.net/reports/FBgn0002555.html gene 16-Dec-15 2015_12 "visible,female sterile" "sternite,macrochaeta" FBgn0022963 splinter splinter http://flybase.net/reports/FBgn0022963.html gene 16-Dec-15 2015_12 FBgn0065354 l(2)SH1775 lethal (2) SH1775 http://flybase.net/reports/FBgn0065354.html gene l(2)SH2 1775 16-Dec-15 2015_12 "lethal,recessive" FBgn0033501 CG12911 http://flybase.net/reports/FBgn0033501.html protein_coding_gene CG12911 16-Dec-15 2015_12 "viable,fertile" FBgn0037261 CG9775 http://flybase.net/reports/FBgn0037261.html protein_coding_gene IPR025715=Friend of PRMT1 duplication CG9775 16-Dec-15 2015_12 ENSXETG00000015918(Q5M8K4_XENTR) ENSG00000160679(CHTOP) viable DRSC22667 IE 2.748252541 -0.516737251 3.175856949 2.073436003 0.028200923 -0.726305087 FBgn0052023 CG32023 http://flybase.net/reports/FBgn0052023.html "FBtr0076588, FBpp0076315" protein_coding_gene CG32023 16-Dec-15 2015_12 FBgn0025506 l(3)72Fa lethal (3) 72Fa http://flybase.net/reports/FBgn0025506.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of first instar larval stage,some die during first instar larval stage" FBgn0065716 l(2)SH0578 lethal (2) SH0578 http://flybase.net/reports/FBgn0065716.html gene l(2)SH2 0578 16-Dec-15 2015_12 "lethal,recessive" FBgn0005048 exr extra venation http://flybase.net/reports/FBgn0005048.html gene 16-Dec-15 2015_12 "viable,female sterile,recessive,male fertile,visible" "eye,wing vein,wing" FBgn0024628 l(2)k15306 lethal (2) k15306 http://flybase.net/reports/FBgn0024628.html gene 153/6 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0267801 CR46126 http://flybase.net/reports/FBgn0267801.html non_protein_coding_gene CR46126 16-Dec-15 2015_12 FBgn0013624 l(3)neo15 lethal (3) neo15 http://flybase.net/reports/FBgn0013624.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0034724 babos babos http://flybase.net/reports/FBgn0034724.html protein_coding_gene 0048814=regulation of dendrite morphogenesis 0098595=perivitelline space "CT12183, CG3624, Cell adhesion protein, Babos" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR007110=Immunoglobulin-like domain, IPR013151=Immunoglobulin" CG3624 16-Dec-15 2015_12 "neuroanatomy defective,viable,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,embryonic/larval hemocyte | third instar larval stage,dendrite | third instar larval stage,LNv neuron" FBgn0031952 cdc14 cell division cycle 14 http://flybase.net/reports/FBgn0031952.html protein_coding_gene "0008138=protein tyrosine/serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0004722=protein serine/threonine phosphatase activity" "0007096=regulation of exit from mitosis, 0006470=protein dephosphorylation, 0035335=peptidyl-tyrosine dephosphorylation" 0005634=nucleus "CDC-14, CDC14, CG7134, cdc14, Cdc14, unnamed" "IPR029021=Protein-tyrosine phosphatase-like, IPR029260=Dual specificity/tyrosine protein phosphatase, N-terminal, IPR026070=Tyrosine-protein phosphatase CDC14, IPR016130=Protein-tyrosine phosphatase, active site, IPR000340=Dual specificity phosphatase, catalytic domain, IPR000387=Tyrosine specific protein phosphatases domain" CG7134 16-Dec-15 2015_12 "ENSDARG00000057016(cdc14ab),ENSDARG00000013858(cdc14aa),ENSDARG00000021483(cdc14b)" YFR028C(CDC14) "ENSXETG00000013234(CDC14A),ENSXETG00000014839(CDC14B)" "ENSMUSG00000033502(Cdc14a),ENSMUSG00000033102(Cdc14b)" "ENSG00000079335(CDC14A),ENSG00000081377(CDC14B)" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage FBgn0010902 l(3)06803 lethal (3) 06803 http://flybase.net/reports/FBgn0010902.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0262592 CG43127 http://flybase.net/reports/FBgn0262592.html "FBgn0085266, FBgn0260394, FBgn0260395" protein_coding_gene "CG34237, CG42520, CG42519" CG43127 16-Dec-15 2015_12 FBgn0265866 CR44655 http://flybase.net/reports/FBgn0265866.html non_protein_coding_gene lincRNA.990 CR44655 16-Dec-15 2015_12 FBgn0033324 CG14744 http://flybase.net/reports/FBgn0033324.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane IPR004837=Sodium/calcium exchanger membrane region CG14744 16-Dec-15 2015_12 "WBGene00003574(ncx-9),WBGene00003573(ncx-8),WBGene00003575(ncx-10),WBGene00003571(ncx-6)" ENSMUSG00000032754(Slc24a6) ENSG00000089060(SLC24A6) viable FBgn0000970 Fs(2)Etr Female sterile (2) Etre http://flybase.net/reports/FBgn0000970.html gene "Etre, Fs(2)Sz4" 16-Dec-15 2015_12 "female sterile soma-dependent,dominant" "dorsal appendage,egg,chorion" FBgn0033058 CCHa2-R CCHamide-2 receptor http://flybase.net/reports/FBgn0033058.html "FBgn0033057, FBgn0044360" protein_coding_gene "0004946=bombesin receptor activity, 0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity" "0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0031989=bombesin receptor signaling pathway" 0016021=integral component of membrane "CG14593, anon-WO0131005.23, CG14594, CCHa2r" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR001556=Bombesin receptor" CG14593 16-Dec-15 2015_12 "ENSDARG00000054152,ENSDARG00000056620(grpr)" "ENSXETG00000016350(NMBR),ENSXETG00000019750(BRS3)" "ENSMUSG00000031364(Grpr),ENSMUSG00000019865(Nmbr),ENSMUSG00000031130(Brs3)" "ENSG00000126010(GRPR),ENSG00000135577(NMBR),ENSG00000102239(BRS3)" viable DRSC04870 EK -0.398587106 0.732574989 -0.173721557 2.727721214 2.091305807 0.151875494 FBgn0053453 CG33453 http://flybase.net/reports/FBgn0053453.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG33453 16-Dec-15 2015_12 viable FBgn0003708 tipC temperature-induced paralytic C http://flybase.net/reports/FBgn0003708.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0032378 CycY Cyclin Y http://flybase.net/reports/FBgn0032378.html FBgn0062199 protein_coding_gene 0019901=protein kinase binding "0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0048589=developmental growth" "Dcyclin Y, anon-WO0118547.165, Drosophila cyclin Y, CG14939, i182" "IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal, IPR012399=Cyclin Y" CG14939 16-Dec-15 2015_12 "ENSDARG00000062270(zgc:153047),ENSDARG00000063677(LOC557738)" WBGene00022697(ZK353.1) "ENSXETG00000016385(TGas141j24.1),ENSXETG00000008813(CCNY)" "ENSMUSG00000024286(Ccny),ENSMUSG00000070871(Ccnyl1)" "ENSG00000108100(CCNY),ENSG00000163249(CCNYL1)" viable FBgn0266915 CR45375 http://flybase.net/reports/FBgn0266915.html non_protein_coding_gene CR45375 16-Dec-15 2015_12 FBgn0003051 Pdr Purpleoider http://flybase.net/reports/FBgn0003051.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0267352 BG01272 http://flybase.net/reports/FBgn0267352.html gene 16-Dec-15 2015_12 "short lived,male,heat stress response defective,female,starvation stress response defective" macrochaeta FBgn0038125 CG8141 http://flybase.net/reports/FBgn0038125.html FBgn0062508 protein_coding_gene 0008270=zinc ion binding BcDNA:AT26376 "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG8141 16-Dec-15 2015_12 viable FBgn0001134 Grd Glycine receptor http://flybase.net/reports/FBgn0001134.html protein_coding_gene "0015276=ligand-gated ion channel activity, 0016933=extracellular-glycine-gated ion channel activity, 0004890=GABA-A receptor activity, 0005230=extracellular ligand-gated ion channel activity" 0006811=ion transport "0005886=plasma membrane, 0016021=integral component of membrane" "CT22917, GRD, CG7446, GABA-and-glycine-receptor-like-subunit-of-Drosophila, GABA and glycine-like receptor of Drosophila, DmGABA(GRD), GABA/Glycine-gated chloride channel-like" "IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG7446 16-Dec-15 2015_12 "ENSDARG00000070005(LOC556056),ENSDARG00000037386(LOC100150704),ENSDARG00000070730(si:dkey-93p24.1),ENSDARG00000068989(gabra1),ENSDARG00000058736,ENSDARG00000037740(LOC100331726)" WBGene00013914(lgc-37) "ENSXETG00000026177(GABRA3),ENSXETG00000010239(GABRA6),ENSXETG00000008421(GABRA2),ENSXETG00000027302(GABRA5)" "ENSMUSG00000031343(Gabra3),ENSMUSG00000000560(Gabra2),ENSMUSG00000055078(Gabra5),ENSMUSG00000010803(Gabra1),ENSMUSG00000020428(Gabra6),ENSMUSG00000029211(Gabra4)" "ENSG00000022355(GABRA1),ENSG00000151834(GABRA2),ENSG00000186297(GABRA5),ENSG00000011677(GABRA3),ENSG00000109158(GABRA4),ENSG00000145863(GABRA6)" viable FBgn0044377 anon-AE003538.2 anon-AE003538.2 http://flybase.net/reports/FBgn0044377.html gene unnamed 16-Dec-15 2015_12 FBgn0040804 CG13453 http://flybase.net/reports/FBgn0040804.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260386 mtg mind the gap http://flybase.net/reports/FBgn0260386.html "FBgn0060301, FBgn0028084, FBgn0037559" protein_coding_gene "0008061=chitin binding, 0097367=carbohydrate derivative binding" "0007274=neuromuscular synaptic transmission, 0050807=regulation of synapse organization, 0006030=chitin metabolic process, 0007416=synapse assembly" "0005615=extracellular space, 0005576=extracellular region, 0043195=terminal bouton, 0043083=synaptic cleft" "l(3)S084910, l(3)S084910b, 0849/10, Mtg, Mind-the-Gap, Mind the gap, CG7549, lethal (3) S084910b" IPR002557=Chitin binding domain CG7549 16-Dec-15 2015_12 FBgn0002727 mfd myofibrillar defect http://flybase.net/reports/FBgn0002727.html gene 16-Dec-15 2015_12 FBgn0066317 29B70 29B70 http://flybase.net/reports/FBgn0066317.html gene 0016319=mushroom body development 16-Dec-15 2015_12 "embryonic/larval mushroom body,somatic clone" FBgn0085764 CR40668 http://flybase.net/reports/FBgn0085764.html FBan0040668 rRNA_gene CR40668 16-Dec-15 2015_12 FBgn0005444 l(1)v150 lethal (1) v150 http://flybase.net/reports/FBgn0005444.html gene l(1)150 16-Dec-15 2015_12 FBgn0022302 l(1)L60.6 lethal (1) L60.6 http://flybase.net/reports/FBgn0022302.html gene L60.6 16-Dec-15 2015_12 "lethal,recessive" FBgn0058370 CG40370 http://flybase.net/reports/FBgn0058370.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265690 CR44497 http://flybase.net/reports/FBgn0265690.html non_protein_coding_gene lincRNA.113 CR44497 16-Dec-15 2015_12 FBgn0082592 fiddler-crab fiddler-crab http://flybase.net/reports/FBgn0082592.html gene 0007411=axon guidance fiddler crab 16-Dec-15 2015_12 FBgn0003748 Treh Trehalase http://flybase.net/reports/FBgn0003748.html "FBgn0014436, FBgn0025313, FBgn0034584" protein_coding_gene "0015927=trehalase activity, 0004555=alpha,alpha-trehalase activity" "0097150=neuronal stem cell maintenance, 0005991=trehalose metabolic process" "trehalase, CG9364, 87D3T, TREH, Tre, anon-sts38, anon-EST:Posey159, ESTS:87D3T, TRE" "IPR008928=Six-hairpin glycosidase-like, IPR001661=Glycoside hydrolase, family 37, IPR018232=Glycoside hydrolase, family 37, conserved site" CG9364 16-Dec-15 2015_12 "YDR001C(NTH1),YBR001C(NTH2)" WBGene00006607(tre-1) ENSXETG00000021551(TREH) ENSMUSG00000032098(Treh) ENSG00000118094(TREH) "viable,fertile,visible,planar polarity defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0032523 CG16956 http://flybase.net/reports/FBgn0032523.html protein_coding_gene CG16956 16-Dec-15 2015_12 viable FBgn0082930 snoRNA:Me28S-G2703b snoRNA:Me28S-G2703b http://flybase.net/reports/FBgn0082930.html snoRNA_gene "Me28S-Gm2703b, CR34540" CR34540 16-Dec-15 2015_12 FBgn0026342 Su(tor)2-113-31 Su(tor)2-113-31 http://flybase.net/reports/FBgn0026342.html gene 16-Dec-15 2015_12 FBgn0037504 CG1142 http://flybase.net/reports/FBgn0037504.html protein_coding_gene IPR014810=Fcf2 pre-rRNA processing CG1142 16-Dec-15 2015_12 ENSDARG00000057648(dnttip2) YLR051C(FCF2) WBGene00021715(Y49F6B.2) FBgn0025347 anon-11b anon-11b http://flybase.net/reports/FBgn0025347.html gene 16-Dec-15 2015_12 FBgn0087014 l(3)61Db-S lethal (3) 61Db of Saito http://flybase.net/reports/FBgn0087014.html gene l(3)61Db 16-Dec-15 2015_12 lethal FBgn0004168 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A http://flybase.net/reports/FBgn0004168.html protein_coding_gene "0001586=Gi/o-coupled serotonin receptor activity, 0008227=G-protein coupled amine receptor activity, 0004993=serotonin receptor activity" "0007198=adenylate cyclase-inhibiting serotonin receptor signaling pathway, 0007615=anesthesia-resistant memory, 0045187=regulation of circadian sleep/wake cycle, sleep, 0007210=serotonin receptor signaling pathway, 0007208=phospholipase C-activating serotonin receptor signaling pathway, 0008049=male courtship behavior, 0002121=inter-male aggressive behavior" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "5HT1A, Serotonin receptor 1A, 5-HT1ADro, 5-HT[[1ADro]], CG16720, 5HT-dro2A, 5-HT[1A]Dro, 5-HT-dro2A, 5-HT[[1A]], Dm5HTdro2A, 5HT-drp[[2A]], 5HT-R2A, Serotonin receptor 2A, 5HT[[1ADro]], 5htdro2a, d5-HT1A, serotonin-receptor-2A, 5-HT[[1A]]DRO, DRO2A" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG16720 16-Dec-15 2015_12 "ENSDARG00000034438(htr1aa),ENSDARG00000057098" WBGene00004779(ser-4) "ENSMUSG00000049511(Htr1b),ENSMUSG00000070687(Htr1d),ENSMUSG00000050783(Htr1f),ENSMUSG00000021721(Htr1a)" ENSG00000178394(HTR1A) " embryonic stage | stage 16-17 , embryonic stage | stage 16,17 " " ventral midline

, embryonic central nervous system

, VUM neuron

" "starvation stress response defective,short lived,cold stress response defective,behavior defective,heat stress response defective,memory defective" FBgn0051563 CG31563 http://flybase.net/reports/FBgn0051563.html protein_coding_gene 16-Dec-15 2015_12 "viable,lethal - all die before end of pupal stage,some die during pupal stage" DRSC21338 K -1.382546749 1.27048122 -0.867556727 -0.129577522 -0.757207174 -1.692280197 FBgn0039083 CG10177 http://flybase.net/reports/FBgn0039083.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0006468=protein phosphorylation, 0045792=negative regulation of cell size, 0035556=intracellular signal transduction, 0007030=Golgi organization" MLCK-like "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR003533=Doublecortin domain" CG10177 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0003298 rud ruddle http://flybase.net/reports/FBgn0003298.html gene 16-Dec-15 2015_12 "viable,good,fertile,visible,recessive,eye color defective" pigment cell FBgn0065402 l(2)SH1602 lethal (2) SH1602 http://flybase.net/reports/FBgn0065402.html gene l(2)SH2 1602 16-Dec-15 2015_12 "lethal,recessive" FBgn0082909 60-16 60-16 http://flybase.net/reports/FBgn0082909.html gene 16-Dec-15 2015_12 FBgn0023114 anon-10At anon-10At http://flybase.net/reports/FBgn0023114.html gene 13 16-Dec-15 2015_12 FBgn0028126 l(3)S057809a lethal (3) S057809a http://flybase.net/reports/FBgn0028126.html gene "l(3)S057809, l(3)s057809, 0578/09" 16-Dec-15 2015_12 "lethal,recessive" FBgn0085528 CG40862 http://flybase.net/reports/FBgn0085528.html FBan0040862 protein_coding_gene 16-Dec-15 2015_12 FBgn0259664 B0751 http://flybase.net/reports/FBgn0259664.html gene 16-Dec-15 2015_12 visible "submarginal cell,wing" FBgn0085834 CR42217 http://flybase.net/reports/FBgn0085834.html FBan0042217 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0259320 EP-M http://flybase.net/reports/FBgn0259320.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0016767 anon-17Cd anon-17Cd http://flybase.net/reports/FBgn0016767.html gene "Transcription unit C4, C4" 16-Dec-15 2015_12 " adult stage | female , embryonic stage | early " FBgn0044115 E(rst)C14 E(rst)C14 http://flybase.net/reports/FBgn0044115.html gene 0001745=compound eye morphogenesis C14 16-Dec-15 2015_12 viable FBgn0259366 EP-634.2 http://flybase.net/reports/FBgn0259366.html gene 16-Dec-15 2015_12 visible "wing hair,wing margin,wing vein,chaeta" FBgn0002516 l(3)Sp10 lethal (3) Sp10 http://flybase.net/reports/FBgn0002516.html gene 16-Dec-15 2015_12 lethal FBgn0259373 EP-284 http://flybase.net/reports/FBgn0259373.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0036594 CG13047 http://flybase.net/reports/FBgn0036594.html protein_coding_gene CG13047 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011993 tRNA:T:90Ca transfer RNA:thr:90Ca http://flybase.net/reports/FBgn0011993.html "FBgn0003833, FBgn0051589, FBgn0060045" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033437=ACU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3R.trna55-ThrAGT, CR31589, tRNA:thr:90Ca, AE002708.trna49-ThrAGT, tRNA[[Thr]], tRNA:T:AGT:AE002708-d" CR31589 16-Dec-15 2015_12 FBgn0065489 l(2)SH1238 lethal (2) SH1238 http://flybase.net/reports/FBgn0065489.html gene l(2)SH2 1238 16-Dec-15 2015_12 "lethal,recessive" FBgn0259348 C603 http://flybase.net/reports/FBgn0259348.html gene 16-Dec-15 2015_12 visible "wing hair,wing,wing vein,chaeta" FBgn0030966 CG7280 http://flybase.net/reports/FBgn0030966.html protein_coding_gene "0030151=molybdenum ion binding, 0020037=heme binding, 0008482=sulfite oxidase activity" "0055114=oxidation-reduction process, 0042128=nitrate assimilation, 0030163=protein catabolic process, 0006790=sulfur compound metabolic process" 0005758=mitochondrial intermembrane space "IPR001199=Cytochrome b5-like heme/steroid binding domain, IPR018506=Cytochrome b5, heme-binding site, IPR000572=Oxidoreductase, molybdopterin-binding domain, IPR005066=Moybdenum cofactor oxidoreductase, dimerisation, IPR008335=Eukaryotic molybdopterin oxidoreductase, IPR014756=Immunoglobulin E-set" CG7280 16-Dec-15 2015_12 WBGene00010397(H13N06.4) ENSXETG00000009446(SUOX) ENSMUSG00000049858(Suox) ENSG00000139531(SUOX) viable FBgn0010769 l(3)02104 lethal (3) 02104 http://flybase.net/reports/FBgn0010769.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035639 CG5537 http://flybase.net/reports/FBgn0035639.html FBgn0025533 protein_coding_gene 0004845=uracil phosphoribosyltransferase activity "uprt, anon-EST:Posey275" IPR029057=Phosphoribosyltransferase-like CG5537 16-Dec-15 2015_12 ENSDARG00000035549(zgc:77421) YHR128W(FUR1) WBGene00008131(C47B2.2) ENSXETG00000004579(UPRT) ENSMUSG00000073016(Uprt) ENSG00000094841(UPRT) viable DRSC10515 I 1.571681505 -0.069839514 0.52852737 0.138679518 -0.12533288 0.765727549 FBgn0010811 l(3)03691 lethal (3) 03691 http://flybase.net/reports/FBgn0010811.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061011 l(3)S026203b lethal (3) S026203b http://flybase.net/reports/FBgn0061011.html gene 0262/03 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0060373 l(3)S136708 lethal (3) S136708 http://flybase.net/reports/FBgn0060373.html gene 1367/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038789 Ir92a Ionotropic receptor 92a http://flybase.net/reports/FBgn0038789.html protein_coding_gene "0036081=extracellular ammonia-gated ion channel activity, 0004984=olfactory receptor activity, 0004970=ionotropic glutamate receptor activity" "0050850=positive regulation of calcium-mediated signaling, 0071418=cellular response to amine stimulus, 0050911=detection of chemical stimulus involved in sensory perception of smell, 1903718=cellular response to ammonia" "0016021=integral component of membrane, 0016020=membrane" "CG15685, DmelIR92a, ionotropic receptor 92a, IR92a" IPR001320=Ionotropic glutamate receptor CG15685 16-Dec-15 2015_12 "viable,smell perception defective" sensillum coeloconicum of antennal segment 3 FBgn0033431 CG1827 http://flybase.net/reports/FBgn0033431.html protein_coding_gene 0003948=N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 0006517=protein deglycosylation 0005764=lysosome cg1827 "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000246=Peptidase T2, asparaginase 2" CG1827 16-Dec-15 2015_12 ENSDARG00000004889 WBGene00019867(R04B3.2) ENSXETG00000009427(AGA) ENSMUSG00000031521(Aga) ENSG00000038002(AGA) viable FBgn0065495 l(2)SH1224 lethal (2) SH1224 http://flybase.net/reports/FBgn0065495.html gene l(2)SH2 1224 16-Dec-15 2015_12 "lethal,recessive" FBgn0053642 CG33642 http://flybase.net/reports/FBgn0053642.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33642 16-Dec-15 2015_12 viable FBgn0003357 Jon99Ciii Jonah 99Ciii http://flybase.net/reports/FBgn0003357.html "FBgn0001288, FBgn0011833, FBgn0051362" protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" "0006508=proteolysis, 0007586=digestion" "99Calpha, Jon99C1, Jonah 99C Alpha, Jon99Calpha, JonC, Jon99Calphaii, Ser2, Serine protease 2, Ser99Db, Ser5, Jonah 99C Beta, Jon99C, SER2, Jon99Cbetaiii, Serine protease 5, SP143, Jon99B, Jon99C2, CG15519, CG31362, Jon99Cbeta" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG31362 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" FBgn0013341 Su(var)25F26B Su(var)25F26B http://flybase.net/reports/FBgn0013341.html gene "unnamed, Suppressor in 26B" 16-Dec-15 2015_12 FBgn0002200 l(3)67Ad lethal (3) 67Ad http://flybase.net/reports/FBgn0002200.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0266967 CR45418 http://flybase.net/reports/FBgn0266967.html non_protein_coding_gene CR45418 16-Dec-15 2015_12 FBgn0016821 l(1)L8 lethal (1) L8 http://flybase.net/reports/FBgn0016821.html gene L8 16-Dec-15 2015_12 "lethal,recessive" FBgn0003429 slo slowpoke http://flybase.net/reports/FBgn0003429.html FBgn0046797 protein_coding_gene "0005515=protein binding, 0060072=large conductance calcium-activated potassium channel activity, 0005249=voltage-gated potassium channel activity, 0015269=calcium-activated potassium channel activity" "0008582=regulation of synaptic growth at neuromuscular junction, 1900074=negative regulation of neuromuscular synaptic transmission, 0006813=potassium ion transport, 0071805=potassium ion transmembrane transport, 0042493=response to drug, 0007623=circadian rhythm, 0045433=male courtship behavior, veined wing generated song production, 0048512=circadian behavior" "0005886=plasma membrane, 0016020=membrane, 0043025=neuronal cell body, 0008076=voltage-gated potassium channel complex, 0043005=neuron projection" "Slo, Dslo, BcDNA:GH10751, Slo1, dSlo1, dSlo, Slowpoke, dslo, CG10693, fSlo" "IPR003091=Potassium channel, IPR003929=Potassium channel, calcium-activated, BK, alpha subunit, IPR016040=NAD(P)-binding domain, IPR005821=Ion transport domain, IPR024939=Calcium-activated potassium channel Slo" CG10693 16-Dec-15 2015_12 WBGene00004830(slo-1) ENSXETG00000018041(KCNMA1) ENSMUSG00000063142(Kcnma1) ENSG00000156113(KCNMA1) adult stage adult head

"flight defective,viable,fertile,chemosensitive behavior defective,neurophysiology defective,chemical sensitive,circadian rhythm defective,recessive,behavior defective,chemical resistant,neuroanatomy defective,courtship behavior defective,male,heat sensitive,lethal" "antennal basiconic sensillum ab12,adult olfactory receptor neuron ab11a,indirect flight muscle,neuron,NMJ bouton,supernumerary,neuromuscular junction,muscle fiber,heat sensitive,neuromuscular junction | heat sensitive" FBgn0024688 aos::vn argos::vn http://flybase.net/reports/FBgn0024688.html engineered_fusion_gene "argos::vn, gil::vn" 16-Dec-15 2015_12 visible "wing vein,eye,ommatidium,anterior crossvein,wing,ectopic,posterior" FBgn0022083 l(2)k07509 lethal (2) k07509 http://flybase.net/reports/FBgn0022083.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037410 Osi2 Osiris 2 http://flybase.net/reports/FBgn0037410.html protein_coding_gene 0005887=integral component of plasma membrane "CG1148, Osiris" IPR012464=Protein of unknown function DUF1676 CG1148 16-Dec-15 2015_12 "viable,fertile" FBgn0037186 CG11241 http://flybase.net/reports/FBgn0037186.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0008453=alanine-glyoxylate transaminase activity" "IPR005814=Aminotransferase class-III, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase" CG11241 16-Dec-15 2015_12 ENSDARG00000056812 WBGene00020382(T09B4.8) ENSXETG00000000707(AGXT2) ENSMUSG00000005269 ENSG00000113492(AGXT2) FBgn0036815 HipHop HP1-HOAP-interacting protein http://flybase.net/reports/FBgn0036815.html "FBgn0011460, FBgn0063064" protein_coding_gene "0034080=CENP-A containing nucleosome assembly, 0022008=neurogenesis, 0031848=protection from non-homologous end joining at telomere" "0000781=chromosome, telomeric region" "HP1 and HOAP-interacting protein, l(3)neo26, lethal (3) neo26, hiphop, BcDNA:RE10558, HIPHOP, CG6874" CG6874 16-Dec-15 2015_12 "lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0033280 CG12126 http://flybase.net/reports/FBgn0033280.html FBgn0065006 protein_coding_gene BcDNA:AT16918 CG12126 16-Dec-15 2015_12 viable FBgn0027112 mei-P8 mei-P8 http://flybase.net/reports/FBgn0027112.html gene 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0266147 CR44853 http://flybase.net/reports/FBgn0266147.html non_protein_coding_gene CR44853 16-Dec-15 2015_12 FBgn0002477 l(3)SG32 lethal (3) SG32 http://flybase.net/reports/FBgn0002477.html gene l(3)C21L 16-Dec-15 2015_12 "lethal,recessive" FBgn0002148 l(2)K534 lethal (2) K534 http://flybase.net/reports/FBgn0002148.html gene 16-Dec-15 2015_12 lethal FBgn0025128 su(RpII140Z36)S19 su(RpII140Z36)S19 http://flybase.net/reports/FBgn0025128.html gene Z36[S19] 16-Dec-15 2015_12 FBgn0267174 CR45614 http://flybase.net/reports/FBgn0267174.html non_protein_coding_gene CR45614 16-Dec-15 2015_12 FBgn0024576 l(3)rK344 lethal (3) rK344 http://flybase.net/reports/FBgn0024576.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061049 l(3)S023434b lethal (3) S023434b http://flybase.net/reports/FBgn0061049.html gene 0234/34 16-Dec-15 2015_12 "lethal,recessive" FBgn0022239 l(2)k02505 lethal (2) k02505 http://flybase.net/reports/FBgn0022239.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035830 CG8209 http://flybase.net/reports/FBgn0035830.html FBgn0046458 protein_coding_gene 0046872=metal ion binding "0005737=cytoplasm, 0005634=nucleus" "anon-WO0172774.138, UBA/UBX 33.3 kDa protein like" "IPR015940=Ubiquitin-associated domain, IPR007087=Zinc finger, C2H2, IPR029071=Ubiquitin-related domain, IPR001012=UBX domain, IPR009060=UBA-like, IPR015880=Zinc finger, C2H2-like" CG8209 16-Dec-15 2015_12 ENSDARG00000004659(ubxn1) WBGene00017733(ubxn-1) ENSXETG00000005477(BC074627.1) ENSMUSG00000071655(Ubxn1) ENSG00000162191(UBXN1) "viable,fertile" FBgn0062580 Mod(var)26 Mod(var)26 http://flybase.net/reports/FBgn0062580.html gene 0006342=chromatin silencing 26 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0051342 CG31342 http://flybase.net/reports/FBgn0051342.html "FBgn0038101, FBgn0038103" protein_coding_gene "CG7472, CG18551" CG31342 16-Dec-15 2015_12 FBgn0028185 l(3)S024020a lethal (3) S024020a http://flybase.net/reports/FBgn0028185.html gene "l(3)S024020, 0240/20" 16-Dec-15 2015_12 "viable,lethal,recessive" FBgn0002830 ms(2)E9 male sterile (2) E9 http://flybase.net/reports/FBgn0002830.html gene "ms(2)2.9, ms2.9" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0060478 l(3)S111116b lethal (3) S111116b http://flybase.net/reports/FBgn0060478.html gene 1111/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0038643 CG14300 http://flybase.net/reports/FBgn0038643.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14300 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0036942 CG7328 http://flybase.net/reports/FBgn0036942.html protein_coding_gene "0008865=fructokinase activity, 0004454=ketohexokinase activity" 0046835=carbohydrate phosphorylation 0005737=cytoplasm "IPR002173=Carbohydrate/puine kinase, PfkB, conserved site, IPR011611=Carbohydrate kinase PfkB, IPR029056=Ribokinase-like" CG7328 16-Dec-15 2015_12 ENSDARG00000029874(khk) ENSXETG00000001220(KHK) ENSMUSG00000029162(Khk) ENSG00000138030(KHK) viable DRSC10812 K 0.606226763 0.042808107 -1.140026465 0.332921219 -0.024964772 2.220670415 FBgn0015496 l(3)65ACf lethal (3) 65ACf http://flybase.net/reports/FBgn0015496.html gene "Distal W5.4 Group VI, l(3)k65ACf, VI" 16-Dec-15 2015_12 "lethal,recessive" FBgn0000010 aa anarista http://flybase.net/reports/FBgn0000010.html gene "aristaless-b, al-b" 16-Dec-15 2015_12 "visible,recessive" "arista,wing" FBgn0050413 CG30413 http://flybase.net/reports/FBgn0050413.html protein_coding_gene CG30413 16-Dec-15 2015_12 viable FBgn0033090 CG15909 http://flybase.net/reports/FBgn0033090.html protein_coding_gene CG15909 16-Dec-15 2015_12 viable FBgn0016990 ms(3)1342A ms(3)1342A http://flybase.net/reports/FBgn0016990.html gene 16-Dec-15 2015_12 FBgn0019788 l(1)15 lethal (1) 15 http://flybase.net/reports/FBgn0019788.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033225 CG1550 http://flybase.net/reports/FBgn0033225.html protein_coding_gene 0004835=tubulin-tyrosine ligase activity 0006464=cellular protein modification process "IPR027749=Tubulin--tyrosine ligase-like protein 12, IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase" CG1550 16-Dec-15 2015_12 ENSDARG00000017407 WBGene00008405(ttll-12) ENSXETG00000015604(TTLL12) ENSMUSG00000016757(Ttll12) ENSG00000100304(TTLL12) viable FBgn0004928 l(3)mbn2 lethal (3) malignant blood neoplasm 2 http://flybase.net/reports/FBgn0004928.html gene l(3)mbn-2 16-Dec-15 2015_12 lethal FBgn0020582 anon-59Cc anon-59Cc http://flybase.net/reports/FBgn0020582.html gene 16-Dec-15 2015_12 FBgn0029508 Tsp42Ea Tetraspanin 42Ea http://flybase.net/reports/FBgn0029508.html "FBgn0033123, FBgn0042099, FBgn0042140, FBgn0064940" protein_coding_gene 0016021=integral component of membrane "Q9U3V4, Dm.Tsp42Ea, CG3364, BcDNA:GM15292, BcDNA:GH05668, GH05668, tetraspanin 42E, CG18742, CG18817" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin" CG18817 16-Dec-15 2015_12 FBgn0005037 Est-9 Esterase 9 http://flybase.net/reports/FBgn0005037.html gene "EST-9, Est9, EST9" 16-Dec-15 2015_12 electrophoretic variant FBgn0005018 dk dark http://flybase.net/reports/FBgn0005018.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0263034 CG43329 http://flybase.net/reports/FBgn0263034.html "FBgn0037168, FBan0012377" protein_coding_gene CG12377 CG43329 16-Dec-15 2015_12 FBgn0061035 l(3)S023941a lethal (3) S023941a http://flybase.net/reports/FBgn0061035.html gene 0239/41 16-Dec-15 2015_12 lethal FBgn0003987 vnl venula http://flybase.net/reports/FBgn0003987.html gene 16-Dec-15 2015_12 wing vein FBgn0000607 E(wa) Enhancer of white-apricot http://flybase.net/reports/FBgn0000607.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,female sterile" FBgn0000881 fs(1)M79 female sterile (1) M79 http://flybase.net/reports/FBgn0000881.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0032798 CG10132 http://flybase.net/reports/FBgn0032798.html protein_coding_gene 0005875=microtubule associated complex "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007111=NACHT nucleoside triphosphatase, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site" CG10132 16-Dec-15 2015_12 viable FBgn0259604 B1514 http://flybase.net/reports/FBgn0259604.html gene 16-Dec-15 2015_12 visible wing FBgn0067897 IM7 Immune induced molecule 7 http://flybase.net/reports/FBgn0067897.html gene 0006952=defense response 0005576=extracellular region DIM 7 16-Dec-15 2015_12 FBgn0265707 CR44514 http://flybase.net/reports/FBgn0265707.html non_protein_coding_gene "incRNA.404, lincRNA.404" CR44514 16-Dec-15 2015_12 FBgn0015492 l(3)65ACb lethal (3) 65ACb http://flybase.net/reports/FBgn0015492.html gene "II, Distal W5.4 Group II" 16-Dec-15 2015_12 "lethal,recessive" FBgn0032414 CG17211 http://flybase.net/reports/FBgn0032414.html protein_coding_gene IPR001007=VWFC domain CG17211 16-Dec-15 2015_12 FBgn0002682 mat(2)twg maternal effect twisted gastrulation http://flybase.net/reports/FBgn0002682.html gene 16-Dec-15 2015_12 FBgn0002295 l(3)80Ff lethal (3) 80Ff http://flybase.net/reports/FBgn0002295.html gene "80Ff, l4B, l(3)Lh4B, lethal 4B" 16-Dec-15 2015_12 lethal FBgn0001500 l(1)10Cc lethal (1) 10Cc http://flybase.net/reports/FBgn0001500.html gene "L20, HA10, HA-10, l(1)L20" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0004744 l(3)85Fa lethal (3) 85Fa http://flybase.net/reports/FBgn0004744.html gene 16-Dec-15 2015_12 lethal FBgn0053255 CR33255 http://flybase.net/reports/FBgn0053255.html pseudogene_attribute CG33255 CR33255 16-Dec-15 2015_12 FBgn0265370 CR44311 http://flybase.net/reports/FBgn0265370.html non_protein_coding_gene lincRNA.26 CR44311 16-Dec-15 2015_12 FBgn0065636 l(2)SH0769 lethal (2) SH0769 http://flybase.net/reports/FBgn0065636.html gene l(2)SH2 0769 16-Dec-15 2015_12 "lethal,recessive" FBgn0001937 l(2)25Fc lethal (2) 25Fc http://flybase.net/reports/FBgn0001937.html gene l(2)gdh-15 16-Dec-15 2015_12 "lethal,recessive" FBgn0263469 snoRNA:SC35-b http://flybase.net/reports/FBgn0263469.html snoRNA_gene CR43584 16-Dec-15 2015_12 FBgn0002273 l(3)70Aa lethal (3) 70Aa http://flybase.net/reports/FBgn0002273.html gene l(3)ZF1 16-Dec-15 2015_12 lethal FBgn0038796 eIF3gb eIF3g paralogue b http://flybase.net/reports/FBgn0038796.html protein_coding_gene "0008270=zinc ion binding, 0003729=mRNA binding, 0000166=nucleotide binding, 0003743=translation initiation factor activity" "0006413=translational initiation, 0051726=regulation of cell cycle" 0005852=eukaryotic translation initiation factor 3 complex "CG10881, cg10881, eIF3-S4" "IPR017334=Eukaryotic translation initiation factor 3 subunit G, IPR001878=Zinc finger, CCHC-type, IPR024675=Eukaryotic translation initiation factor 3 subunit G, N-terminal, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG10881 16-Dec-15 2015_12 ENSDARG00000016889(eif3g) YDR429C(TIF35) WBGene00001230(eif-3.G) ENSXETG00000027008(eif3s4) ENSMUSG00000070319(Eif3g) ENSG00000130811(EIF3G) lethal DRSC28960 K -0.231662238 -0.036076986 0.322971999 0.975098108 1.819966063 0.16050251 FBgn0011221 goul goulash http://flybase.net/reports/FBgn0011221.html gene 0007286=spermatid development 16-Dec-15 2015_12 male sterile FBgn0019821 eZ6 eZ6 http://flybase.net/reports/FBgn0019821.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0025382 Rab27 Rab27 http://flybase.net/reports/FBgn0025382.html protein_coding_gene "0003924=GTPase activity, 0005515=protein binding, 0005525=GTP binding" "0015031=protein transport, 0032482=Rab protein signal transduction, 1990182=exosomal secretion, 0016192=vesicle-mediated transport, 0030431=sleep" "0008021=synaptic vesicle, 0045202=synapse, 0031982=vesicle" "O76901, 18543235, dm-Rab27, DmRab27, rab27, EG:80H7.4, AAF45635, AAF45634, CG14791" "IPR003579=Small GTPase superfamily, Rab type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG14791 16-Dec-15 2015_12 "ENSDARG00000040532(zgc:114135),ENSDARG00000010660" WBGene00000089(aex-6) "ENSXETG00000007375(rab27a),ENSXETG00000003366(rab27b)" "ENSMUSG00000032202(Rab27a),ENSMUSG00000024511(Rab27b)" "ENSG00000069974(RAB27A),ENSG00000041353(RAB27B)" "viable,fertile,sleep defective" FBgn0038039 CG5196 http://flybase.net/reports/FBgn0038039.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" "0018345=protein palmitoylation, 0007030=Golgi organization" "0005783=endoplasmic reticulum, 0012505=endomembrane system" "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG5196 16-Dec-15 2015_12 WBGene00010892(M18.8) ENSXETG00000018774(ZDHHC6) ENSMUSG00000024982(Zdhhc6) ENSG00000023041(ZDHHC6) viable FBgn0004936 ABO-2R Abnormal Oocyte on 2R http://flybase.net/reports/FBgn0004936.html region ABO 16-Dec-15 2015_12 FBgn0259963 Sfp33A2 Seminal fluid protein 33A2 http://flybase.net/reports/FBgn0259963.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG42473, Seminal fluid protein 33A2" CG42473 16-Dec-15 2015_12 FBgn0002665 mat(2)ea-B maternal effect early arrest B http://flybase.net/reports/FBgn0002665.html gene "mat(2)earlyPG44, early-PG44" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0029001 ms(3)08724 ms(3)08724 http://flybase.net/reports/FBgn0029001.html gene "unnamed, P1732" 16-Dec-15 2015_12 FBgn0262533 CR43087 http://flybase.net/reports/FBgn0262533.html pseudogene_attribute CR43087 16-Dec-15 2015_12 FBgn0267825 L Lobe http://flybase.net/reports/FBgn0267825.html "FBgn0001332, FBgn0010518, FBgn0033940" protein_coding_gene "0035214=eye-antennal disc development, 0030178=negative regulation of Wnt signaling pathway, 0048749=compound eye development, 0046329=negative regulation of JNK cascade, 0045570=regulation of imaginal disc growth, 0043069=negative regulation of programmed cell death" "0005737=cytoplasm, 0005829=cytosol" "lobe, freaky eye, fee" 16-Dec-15 2015_12 FBgn0000269 ccb central complex broad http://flybase.net/reports/FBgn0000269.html gene "0048149=behavioral response to ethanol, 0048036=central complex development" 16-Dec-15 2015_12 "learning defective,recessive,behavior defective,memory defective" "ellipsoid body,supernumerary,adult central complex,fan-shaped body,protocerebral bridge" FBgn0265472 Apc::Apc2 http://flybase.net/reports/FBgn0265472.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0065428 l(2)SH1504 lethal (2) SH1504 http://flybase.net/reports/FBgn0065428.html gene l(2)SH2 1504 16-Dec-15 2015_12 "lethal,recessive" FBgn0001743 l(1)HM13 lethal (1) HM13 http://flybase.net/reports/FBgn0001743.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female sterile" FBgn0005084 fs(2)OW808 female sterile (2) OW808 http://flybase.net/reports/FBgn0005084.html gene 16-Dec-15 2015_12 FBgn0050071 CG30071 http://flybase.net/reports/FBgn0050071.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC22029 E 0.68798794 0.156759211 1.402462133 1.586225263 0.353631181 0.660610817 FBgn0011169 l(1)291-3 lethal (1) 291-3 http://flybase.net/reports/FBgn0011169.html FBgn0010199 gene 291-3 16-Dec-15 2015_12 "lethal,recessive" FBgn0051546 CG31546 http://flybase.net/reports/FBgn0051546.html "FBgn0037355, FBgn0044687" protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "CG2907, anon-WO0140519.189" "IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG31546 16-Dec-15 2015_12 "YIR035C(),YIR036C(IRC24)" ENSMUSG00000030825(Hsd17b14) ENSG00000087076(HSD17B14) viable FBgn0001639 l(1)dn19 lethal (1) discs normal 19 http://flybase.net/reports/FBgn0001639.html gene l(1)d.norm.-19 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263880 l(3)A38 http://flybase.net/reports/FBgn0263880.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0036191 Sugb Sugar baby http://flybase.net/reports/FBgn0036191.html protein_coding_gene 0008340=determination of adult lifespan "Sugar-baby, CG7334, Sug, sug" "IPR020846=Major facilitator superfamily domain, IPR024989=Major facilitator superfamily associated domain" CG7334 16-Dec-15 2015_12 "viable,fertile,long lived" FBgn0052199 CG32199 http://flybase.net/reports/FBgn0052199.html FBgn0036798 protein_coding_gene "0005506=iron ion binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0031418=L-ascorbic acid binding" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" 0016222=procollagen-proline 4-dioxygenase complex CG13382 "IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG32199 16-Dec-15 2015_12 viable FBgn0265850 CR44639 http://flybase.net/reports/FBgn0265850.html non_protein_coding_gene CR44639 16-Dec-15 2015_12 FBgn0036665 CG13024 http://flybase.net/reports/FBgn0036665.html FBgn0062921 protein_coding_gene BcDNA:RH61817 CG13024 16-Dec-15 2015_12 viable FBgn0032437 CR17024 http://flybase.net/reports/FBgn0032437.html pseudogene_attribute CG17024 CR17024 16-Dec-15 2015_12 YAR015W(ADE1) WBGene00015116(B0286.3) ENSXETG00000005615(PAICS) ENSMUSG00000029247(Paics) ENSG00000128050(PAICS) FBgn0032377 CG14937 http://flybase.net/reports/FBgn0032377.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO17 IPR001810=F-box domain CG14937 16-Dec-15 2015_12 viable FBgn0015767 Mst302 Male-specific transcript 302 http://flybase.net/reports/FBgn0015767.html gene 16-Dec-15 2015_12 FBgn0036552 CG17028 http://flybase.net/reports/FBgn0036552.html protein_coding_gene 0008934=inositol monophosphate 1-phosphatase activity "0016311=dephosphorylation, 0046855=inositol phosphate dephosphorylation, 0046854=phosphatidylinositol phosphorylation" 0005737=cytoplasm IMP "IPR020552=Inositol monophosphatase, Lithium-sensitive, IPR000760=Inositol monophosphatase, IPR020550=Inositol monophosphatase, conserved site, IPR020583=Inositol monophosphatase, metal-binding site" CG17028 16-Dec-15 2015_12 "YDR287W(INM2),YHR046C(INM1)" viable DRSC29850 K 0.345656475 0.83111402 0.29969736 -0.129991268 1.610369987 -0.166102827 FBgn0036224 Rpt4R Regulatory particle triple-A ATPase 4-related http://flybase.net/reports/FBgn0036224.html protein_coding_gene "0005524=ATP binding, 0016787=hydrolase activity, 0016887=ATPase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005737=cytoplasm, 0008540=proteasome regulatory particle, base subcomplex" "7257, DmCG7257, CG7257, Dm_Rpt4c" "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR005937=26S proteasome subunit P45" CG7257 16-Dec-15 2015_12 YOR259C(RPT4) WBGene00004504(rpt-4) "partially lethal - majority die,some die during pupal stage" FBgn0263408 CR43454 http://flybase.net/reports/FBgn0263408.html non_protein_coding_gene CR43454 16-Dec-15 2015_12 FBgn0020293 l(1)EH275a lethal (1) EH275a http://flybase.net/reports/FBgn0020293.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0038974 CG5377 http://flybase.net/reports/FBgn0038974.html protein_coding_gene 0017171=serine hydrolase activity "IPR029059=Alpha/beta hydrolase fold-5, IPR029058=Alpha/Beta hydrolase fold" CG5377 16-Dec-15 2015_12 ENSDARG00000031722 WBGene00019280(K01A2.5) ENSXETG00000018034(BPHL) ENSMUSG00000038286(Bphl) ENSG00000137274(BPHL) viable FBgn0053516 dpr3 defective proboscis extension response 3 http://flybase.net/reports/FBgn0053516.html "FBgn0031386, FBgn0031387, FBgn0040716, FBtr0077856, FBpp0077528, FBtr0077857, FBpp0077529, FBtr0077858, FBpp0077530" protein_coding_gene "0007606=sensory perception of chemical stimulus, 0002115=store-operated calcium entry" "CG33516, CRAC modulator 2, dpr3, CG15381, Dpr-3, CG15380, CG15379, CT35425, CRACM2, Dpr3" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain" CG33516 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" "ENSMUSG00000078780(Gm5150),ENSMUSG00000044138(Sirpb1a),ENSMUSG00000078781(Sirpb1b),ENSMUSG00000074677(LOC100038947),ENSMUSG00000037902(Sirpa),ENSMUSG00000078783(Gm9733)" viable FBgn0032585 CG4580 http://flybase.net/reports/FBgn0032585.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain, IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13" CG4580 16-Dec-15 2015_12 viable FBgn0029649 CG4116 http://flybase.net/reports/FBgn0029649.html protein_coding_gene CG4116 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0025483 l(3)Ax27 lethal (3) Ax27 http://flybase.net/reports/FBgn0025483.html gene Ax27 16-Dec-15 2015_12 "lethal,recessive" FBgn0030684 CG8260 http://flybase.net/reports/FBgn0030684.html protein_coding_gene "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG8260 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0000820 fs(1)K1193 female sterile (1) K1193 http://flybase.net/reports/FBgn0000820.html gene 16-Dec-15 2015_12 female sterile FBgn0023177 Pp4-19C Protein phosphatase 19C http://flybase.net/reports/FBgn0023177.html "FBgn0005784, FBgn0031112, FBgn0031113, FBgn0042229, FBgn0052505" protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0016787=hydrolase activity" "0007017=microtubule-based process, 0006470=protein dephosphorylation, 0007346=regulation of mitotic cell cycle, 0000278=mitotic cell cycle, 0022008=neurogenesis" "0005634=nucleus, 0005813=centrosome, 0005737=cytoplasm, 0000775=chromosome, centromeric region, 0030289=protein phosphatase 4 complex" "CG18339, PP4 19C, protein phosphatase 1, PP4-19c, PpX, PPP4c, PP4, DmPpp4-19C, CG1459, dPP4, CG32505, PP1, Ppp4c, PP4-19C, PPX, Protein phosphatase X, pp4, Protein Phosphatase 4, Phosphoprotein phosphatase 4, PP4c, CG1596, PP4C" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like" CG32505 16-Dec-15 2015_12 "ENSDARG00000009595(ppp4ca),ENSDARG00000070570(LOC100330968)" WBGene00004085(pph-4.1) ENSXETG00000020670(ppp4c) ENSMUSG00000030697(Ppp4c) ENSG00000149923(PPP4C) "partially lethal - majority die,maternal effect,recessive,some die during embryonic stage,lethal,neuroanatomy defective,visible,some die during pupal stage,female semi-sterile,female fertile" "centrosome | embryonic stage | maternal effect,microtubule | embryonic stage | maternal effect,mitotic domain,maternal effect,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,synapse,neuromuscular junction" DRSC21251 I -1.040187241 -3.547631511 -1.103693159 -1.353044199 0.049852253 -0.769667735 FBgn0033128 Tsp42Eg Tetraspanin 42Eg http://flybase.net/reports/FBgn0033128.html FBgn0064948 protein_coding_gene 0016021=integral component of membrane "CG12142, BcDNA:GM06962, Dm.Tsp42Eg, tetraspanin 42E" "IPR000301=Tetraspanin, IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG12142 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0037368 CG1239 http://flybase.net/reports/FBgn0037368.html protein_coding_gene 0008168=methyltransferase activity 0022008=neurogenesis cg1239 "IPR010675=Bicoid-interacting 3, IPR024160=Bin3-type S-adenosyl-L-methionine binding domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG1239 16-Dec-15 2015_12 WBGene00012469(Y17G7B.18) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0065368 l(2)SH1709 lethal (2) SH1709 http://flybase.net/reports/FBgn0065368.html gene l(2)SH2 1709 16-Dec-15 2015_12 "lethal,recessive" FBgn0265315 CR44288 http://flybase.net/reports/FBgn0265315.html non_protein_coding_gene CR44288 16-Dec-15 2015_12 FBgn0050390 Sgf29 SAGA-associated factor 29kDa http://flybase.net/reports/FBgn0050390.html FBgn0034613 protein_coding_gene "0035064=methylated histone binding, 0004402=histone acetyltransferase activity" "0016573=histone acetylation, 0006338=chromatin remodeling, 0043966=histone H3 acetylation" "0005634=nucleus, 0000124=SAGA complex, 0005671=Ada2/Gcn5/Ada3 transcription activator complex" "dSgf29, SAGA-associated factor 29 ortholog, CG30390, CG10509, Sgf29" IPR010750=SGF29 tudor-like domain CG30390 16-Dec-15 2015_12 ENSDARG00000002339(ccdc101) WBGene00021205(Y17G9B.8) ENSMUSG00000030714(Ccdc101) ENSG00000176476(CCDC101) viable FBgn0004054 zen2 zerknullt-related http://flybase.net/reports/FBgn0004054.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0007450=dorsal/ventral pattern formation, imaginal disc" 0005634=nucleus "zpr, z2, BG:DS00276.10, Zerknullt-related, zerknullt 2, zen-pattern-related, CG1048" "IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG1048 16-Dec-15 2015_12 "ENSDARG00000069327(zgc:113257),ENSDARG00000052550(nkx2.2b)" ENSXETG00000023794() " embryonic stage | 3.5 hr , embryonic stage | embryonic cycle 14 , embryonic stage | extended germ band , embryonic stage | gastrula , embryonic stage | early , embryonic stage " " dorsal fold

, organism | dorsal & anterior

, amnioserosa

, organism | dorsal

, dorsal ectoderm | restricted

, embryo | dorsal

" lethal FBgn0265643 CR44450 http://flybase.net/reports/FBgn0265643.html non_protein_coding_gene lincRNA.268 CR44450 16-Dec-15 2015_12 FBgn0026368 Sbp6 Su(H)-binding protein 6 http://flybase.net/reports/FBgn0026368.html gene 0008134=transcription factor binding sbp6 16-Dec-15 2015_12 FBgn0019804 ksr::tor ksr::tor http://flybase.net/reports/FBgn0019804.html engineered_fusion_gene 16-Dec-15 2015_12 "wild-type,visible,dominant" "eye,eye photoreceptor cell,ommatidium,photoreceptor cell R7" FBgn0262472 EP330 http://flybase.net/reports/FBgn0262472.html gene 16-Dec-15 2015_12 FBgn0001346 l(1)1Ea lethal (1) 1Ea http://flybase.net/reports/FBgn0001346.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,cell lethal,germline clone" FBgn0266862 CR45323 http://flybase.net/reports/FBgn0266862.html non_protein_coding_gene CR45323 16-Dec-15 2015_12 FBgn0011204 cue cueball http://flybase.net/reports/FBgn0011204.html FBgn0035225 protein_coding_gene "0042813=Wnt-activated receptor activity, 0005041=low-density lipoprotein receptor activity, 0017147=Wnt-protein binding" "0060070=canonical Wnt signaling pathway, 0007285=primary spermatocyte growth, 0044332=Wnt signaling pathway involved in dorsal/ventral axis specification" "ms(3)02509, CT5570, CG12086" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR013032=EGF-like, conserved site, IPR000742=EGF-like domain, IPR000033=LDLR class B repeat" CG12086 16-Dec-15 2015_12 "male sterile,recessive,female semi-sterile,viable" "spermatocyte,primary spermatocyte cyst,testis,ovary" FBgn0030577 CG5334 http://flybase.net/reports/FBgn0030577.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0000209=protein polyubiquitination "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR000571=Zinc finger, CCCH-type" CG5334 16-Dec-15 2015_12 WBGene00021924(Y55F3AM.6) FBgn0046793 CG32236 http://flybase.net/reports/FBgn0046793.html "FBgn0045162, FBgn0052236" protein_coding_gene "BcDNA:GH16763, NEST:bs27g09" "IPR029000=Cyclophilin-like domain, IPR029488=KIAA1430 homologue" CG32236 16-Dec-15 2015_12 viable DRSC08117 I 1.54780742 0.302279955 0.014388703 0.000905362 0.9071219 -0.000221745 FBgn0267510 2SrRNA-ë¬:CR45850 2S ribosomal RNA pseudogene:CR45850 http://flybase.net/reports/FBgn0267510.html pseudogene_attribute CR45850 CR45850 16-Dec-15 2015_12 FBgn0027214 l(1)G0332 lethal (1) G0332 http://flybase.net/reports/FBgn0027214.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265677 CR44484 http://flybase.net/reports/FBgn0265677.html non_protein_coding_gene lincRNA.20 CR44484 16-Dec-15 2015_12 FBgn0037024 CG4365 http://flybase.net/reports/FBgn0037024.html protein_coding_gene "0008270=zinc ion binding, 0004416=hydroxyacylglutathione hydrolase activity" 0006750=glutathione biosynthetic process 0005875=microtubule associated complex "IPR001279=Metallo-beta-lactamase, IPR017782=Hydroxyacylglutathione hydrolase" CG4365 16-Dec-15 2015_12 ENSDARG00000025338(hagh) "YDR272W(GLO2),YOR040W(GLO4)" WBGene00012459(Y17G7B.3) ENSXETG00000007202(HAGH) ENSMUSG00000024158(Hagh) ENSG00000063854(HAGH) viable DRSC11755 I 2.252649256 0.202467921 0.21434577 -0.178385661 0.23953024 -0.245308299 FBgn0002252 l(3)68Ed lethal (3) 68Ed http://flybase.net/reports/FBgn0002252.html gene "rsg14, l(3)rsg14, rose-gespleten region interval 14" 16-Dec-15 2015_12 lethal FBgn0065693 l(2)SH0641 lethal (2) SH0641 http://flybase.net/reports/FBgn0065693.html gene l(2)SH2 0641 16-Dec-15 2015_12 "lethal,recessive" FBgn0019624 COX5A Cytochrome c oxidase subunit 5A http://flybase.net/reports/FBgn0019624.html FBgn0023019 protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen, 0045787=positive regulation of cell cycle, 0007406=negative regulation of neuroblast proliferation" "0005743=mitochondrial inner membrane, 0005811=lipid particle, 0005739=mitochondrion, 0005751=mitochondrial respiratory chain complex IV" "cytochrome c oxidase subunit Va, CG14724, cytochrome c oxidase Va, Cytochrome c oxidase Polypeptide Va, cova, Cytochrome c oxidase subunit Va, tend, Va, CYTOCHROME C OXIDASE SUBUNIT Va, Subunit Va, cytochrome C oxidase subunit Va, subunit Va of complex IV, Cytochrome c oxidase Va, mt precursor, Cytochrome c oxidase polypeptide Va, cytochrome oxidase subunit Va, COXA, CoVa, cytochrome-c oxidase subunit Va, COXA_DROME, cytochrome c oxidase subunit Va preprotein, COX, tenured, Cytochrome oxidase Va, Cytochrome c oxidase Va" "IPR003204=Cytochrome c oxidase, subunit Va/VI" CG14724 16-Dec-15 2015_12 "ENSDARG00000018119(cox5ab),ENSDARG00000017906(cox5aa)" YHR051W(COX6) WBGene00012553(cco-2) ENSXETG00000021126(COX5A) ENSMUSG00000000088(Cox5a) ENSG00000178741(COX5A) "lethal,recessive,mitotic cell cycle defective,somatic clone,increased cell number,visible,body color defective,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,lens,eye disc posterior to the morphogenetic furrow,cone cell,ommatidial precursor cluster,lamellocyte | third instar larval stage,eye disc,trichogen cell,mesothoracic tergum" DRSC16611 IK -1.158527569 -1.69573182 -1.018231422 -0.830830332 1.678435299 0.731583849 FBgn0019668 mwr more wright http://flybase.net/reports/FBgn0019668.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive,lethal,maternal effect,partially" FBgn0041741 l(2)44Fr lethal (2) 44Fr http://flybase.net/reports/FBgn0041741.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032888 CheB38c Chemosensory protein B 38c http://flybase.net/reports/FBgn0032888.html protein_coding_gene 0008289=lipid binding "0043695=detection of pheromone, 0007606=sensory perception of chemical stimulus" "0005615=extracellular space, 0005576=extracellular region" "CG14405, CheB38c" "IPR010512=Protein of unknown function DUF1091, IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG14405 16-Dec-15 2015_12 FBgn0030812 CG8949 http://flybase.net/reports/FBgn0030812.html "FBgn0054014, FBgn0082874" protein_coding_gene "CG34014, unnamed, BP1032" IPR001202=WW domain CG8949 16-Dec-15 2015_12 "ENSDARG00000012577(waca),ENSDARG00000056403(wacb)" ENSXETG00000004545(wac) ENSMUSG00000024283(Wac) ENSG00000095787(WAC) FBgn0028134 l(3)S050407b lethal (3) S050407b http://flybase.net/reports/FBgn0028134.html gene 0504/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0262004 CG42822 http://flybase.net/reports/FBgn0262004.html "FBgn0054035, FBgn0082895" protein_coding_gene "BP1011, CG34035" CG42822 16-Dec-15 2015_12 FBgn0083951 CG34115 http://flybase.net/reports/FBgn0083951.html protein_coding_gene CG34115 16-Dec-15 2015_12 FBgn0263516 mir-4958 mir-4958 stem loop http://flybase.net/reports/FBgn0263516.html miRNA_gene "CR43501, dme-mir-4958" CR43501 16-Dec-15 2015_12 FBgn0082914 wst wasted http://flybase.net/reports/FBgn0082914.html gene "0035037=sperm entry, 0046693=sperm storage, 0035041=sperm chromatin decondensation" "wst, wasted" 16-Dec-15 2015_12 "viable,female fertile,male sterile,recessive" male pronucleus FBgn0070022 BG00829 BG00829 http://flybase.net/reports/FBgn0070022.html gene 16-Dec-15 2015_12 stress response defective FBgn0037433 CG17919 http://flybase.net/reports/FBgn0037433.html protein_coding_gene 0043168=anion binding "0009617=response to bacterium, 0032504=multicellular organism reproduction" 0005615=extracellular space "IPR008914=Phosphatidylethanolamine-binding protein PEBP, IPR001858=Phosphatidylethanolamine-binding, conserved site" CG17919 16-Dec-15 2015_12 ENSDARG00000042069(pbp) "YLR179C(),YLR178C(TFS1)" ENSXETG00000022375(pebp) "ENSMUSG00000048362(Gm9824),ENSMUSG00000032959(Pebp1),ENSMUSG00000047104(Pbp2)" ENSG00000089220(PEBP1) "viable,fertile" DRSC27860 K 0.52523435 -0.239638519 0.773168894 0.257416664 1.889964946 3.35145055 FBgn0031407 CG4270 http://flybase.net/reports/FBgn0031407.html FBgn0063357 protein_coding_gene 0005576=extracellular region BcDNA:AT04879 "IPR018244=Allergen V5/Tpx-1-related, conserved site, IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR002413=Ves allergen" CG4270 16-Dec-15 2015_12 ENSDARG00000067652 WBGene00008604(F09B9.5) "viable,visible" mesothoracic tergum DRSC00648 K 1.13659701 -0.209719651 0.358052422 -0.053894389 0.467995676 1.568416809 FBgn0020826 l(3)03647 lethal (3) 03647 http://flybase.net/reports/FBgn0020826.html gene 16-Dec-15 2015_12 FBgn0002554 ll lanceolate http://flybase.net/reports/FBgn0002554.html gene lance-b 16-Dec-15 2015_12 visible "wing,eye,adult head" FBgn0051115 CG31115 http://flybase.net/reports/FBgn0051115.html protein_coding_gene "0017061=S-methyl-5-thioadenosine phosphorylase activity, 0004645=phosphorylase activity" 0009116=nucleoside metabolic process "IPR001369=PNP/MTAP phosphorylase, IPR000845=Nucleoside phosphorylase domain, IPR010044=Methylthioadenosine phosphorylase (MTAP)" CG31115 16-Dec-15 2015_12 YLR017W(MEU1) WBGene00015064(B0228.7) viable FBgn0265267 CG18258 http://flybase.net/reports/FBgn0265267.html "FBgn0030827, FBgn0066947" protein_coding_gene 0052689=carboxylic ester hydrolase activity "anon-SAGE:Wang-051, CT41369" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG18258 16-Dec-15 2015_12 FBgn0002069 Aats-asp Aspartyl-tRNA synthetase http://flybase.net/reports/FBgn0002069.html "FBgn0022204, FBgn0025948" protein_coding_gene "0003676=nucleic acid binding, 0004815=aspartate-tRNA ligase activity, 0005524=ATP binding" "0040007=growth, 0006422=aspartyl-tRNA aminoacylation, 0022008=neurogenesis" "0005737=cytoplasm, 0017101=aminoacyl-tRNA synthetase multienzyme complex, 0005875=microtubule associated complex" "lethal(2)49Db, cDNA1, AspRS, vr1, l(2)vr1, aats-asp, clone 2.49, Aats-Asp, poney, CG3821, l(2)v27, l(2)49Db, DRS, l(2)k04508, anon-EST:Liang-2.49" "IPR004523=Aspartyl-tRNA synthetase, archaeal-type, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR002312=Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR004364=Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365=OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR012340=Nucleic acid-binding, OB-fold, IPR018150=Aminoacyl-tRNA synthetase, class II (D/K/N)-like" CG3821 16-Dec-15 2015_12 ENSDARG00000070043 YLL018C(DPS1) WBGene00001094(dars-1) ENSXETG00000025033(dars) ENSMUSG00000026356(Dars) ENSG00000115866(DARS) embryonic stage "

ubiquitous , embryonic/larval salivary gland

" "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cell autonomous,decreased cell size,somatic clone,wild-type,non-suppressor of variegation,dominant,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "wing disc,cell autonomous,somatic clone,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0034824 Klp59C Kinesin-like protein at 59C http://flybase.net/reports/FBgn0034824.html protein_coding_gene "0005524=ATP binding, 0003774=motor activity, 0008017=microtubule binding, 0003777=microtubule motor activity" "0007018=microtubule-based movement, 0000070=mitotic sister chromatid segregation" "0005871=kinesin complex, 0005828=kinetochore microtubule" "Kinesin-like protein at 59C, DmCG3219, DmKLP59C, KLP59C, Klp59C, KIF 2B, KIF2A/B/C, DmKlp59C, CG3219, kinesin-13" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain, IPR027640=Kinesin-like protein" CG3219 16-Dec-15 2015_12 "mitotic cell cycle defective,viable" "mitosis & nuclear chromosome,microtubule" FBgn0032494 CG5945 http://flybase.net/reports/FBgn0032494.html protein_coding_gene 0005615=extracellular space "CT18564, cg5945" IPR010562=Haemolymph juvenile hormone binding CG5945 16-Dec-15 2015_12 viable FBgn0265696 CR44503 http://flybase.net/reports/FBgn0265696.html non_protein_coding_gene CR44503 16-Dec-15 2015_12 FBgn0001943 l(2)26Ad lethal (2) 26Ad http://flybase.net/reports/FBgn0001943.html gene l(2)gdh-5 16-Dec-15 2015_12 "lethal,recessive" FBgn0005747 l(1)TK239 lethal (1) TK239 http://flybase.net/reports/FBgn0005747.html gene l239 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0014253 l(2)DA2 lethal (2) DA2 http://flybase.net/reports/FBgn0014253.html gene DA2 16-Dec-15 2015_12 "lethal,recessive" FBgn0036580 PDCD-5 Programmed Cell Death 5 http://flybase.net/reports/FBgn0036580.html FBgn0047159 protein_coding_gene 0003677=DNA binding "0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0043065=positive regulation of apoptotic process" "CG13072, Programmed Cell Death gene-5, DMPDCD-5, PDCD-5, Programmed cell death 5, PDCD5, BcDNA:RE17056" IPR002836=PDCD5-related protein CG13072 16-Dec-15 2015_12 ENSDARG00000026072(pdcd5) YMR074C() WBGene00008398(D2005.3) ENSXETG00000013573(PDCD5) ENSG00000105185(PDCD5) "viable,fertile" DRSC09955 E -0.030048743 -0.079465965 -1.523417301 1.718770224 -0.915957609 -0.348538684 FBgn0014917 anon-72ABa anon-72ABa http://flybase.net/reports/FBgn0014917.html gene 16-Dec-15 2015_12 FBgn0052110 CG32110 http://flybase.net/reports/FBgn0052110.html FBgn0043541 protein_coding_gene "0008233=peptidase activity, 0016929=SUMO-specific protease activity" "0006508=proteolysis, 0016926=protein desumoylation" "unnamed, anon-AE003540.1" "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG32110 16-Dec-15 2015_12 "ENSDARG00000068450(senp3a),ENSDARG00000056741(senp3b)" YPL020C(ULP1) "ENSMUSG00000067716(Gm5415),ENSMUSG00000049830(Gm9839),ENSMUSG00000058176" "ENSG00000161956(SENP3),ENSG00000079387(SENP1)" viable FBgn0053225 CG33225 http://flybase.net/reports/FBgn0053225.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG33225 16-Dec-15 2015_12 WBGene00006621(try-3) FBgn0030823 CG8918 http://flybase.net/reports/FBgn0030823.html protein_coding_gene 0018095=protein polyglutamylation "IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027750=Tubulin polyglutamylase TTLL1" CG8918 16-Dec-15 2015_12 WBGene00044187(ttll-9) ENSXETG00000027373(TTLL2) viable FBgn0002507 l(3)SG68 lethal (3) SG68 http://flybase.net/reports/FBgn0002507.html FBgn0004733 gene "SG68, l(3)A2, l(3)dsl2, l(3)dsl-2" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0038888 CheB93a Chemosensory protein B 93a http://flybase.net/reports/FBgn0038888.html protein_coding_gene 0008289=lipid binding "0043695=detection of pheromone, 0007606=sensory perception of chemical stimulus" "0005576=extracellular region, 0005615=extracellular space" "CG15503, CheB93a" "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG15503 16-Dec-15 2015_12 viable FBgn0267159 CR45599 http://flybase.net/reports/FBgn0267159.html non_protein_coding_gene CR45599 16-Dec-15 2015_12 FBgn0065831 l(2)SH0349 lethal (2) SH0349 http://flybase.net/reports/FBgn0065831.html gene l(2)SH2 0349 16-Dec-15 2015_12 "lethal,recessive" FBgn0028664 VhaM9.7-c Vacuolar H+ ATPase M9.7 subunit c http://flybase.net/reports/FBgn0028664.html FBgn0035506 protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033179=proton-transporting V-type ATPase, V0 domain, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "Vacuolar H[+] ATPase subunit M9.7-c, VhaM9.7-1, vhaM9.7-1, CG11589, vhaM9.7-3, vhaM9.2-1" "IPR017385=ATPase, V0 complex, subunit e1/e2, metazoa, IPR008389=ATPase, V0 complex, subunit e1/e2" CG11589 16-Dec-15 2015_12 "ENSDARG00000059057(zgc:109987),ENSDARG00000039642(zgc:103433)" WBGene00009882(vha-17) ENSXETG00000024781(ATP6V0E1) "ENSMUSG00000039347(Atp6v0e2),ENSMUSG00000015575(Atp6v0e)" ENSG00000113732(ATP6V0E1) "viable,visible" trichogen cell FBgn0260326 GSd243 http://flybase.net/reports/FBgn0260326.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,segmental nerve" FBgn0005334 podH podoptera of Hannah http://flybase.net/reports/FBgn0005334.html gene pod-H 16-Dec-15 2015_12 visible wing FBgn0260506 Pkc53E::Mmus\Rtkn http://flybase.net/reports/FBgn0260506.html engineered_fusion_gene Rhot-53E 16-Dec-15 2015_12 FBgn0084211 W145 W145 http://flybase.net/reports/FBgn0084211.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0026352 Su(SuRaf1)A2-1 Su(SuRaf1)A2-1 http://flybase.net/reports/FBgn0026352.html gene Su[Su(Raf)1]A2-1 16-Dec-15 2015_12 "lethal,recessive" FBgn0001647 l(1)dn27 lethal (1) discs normal 27 http://flybase.net/reports/FBgn0001647.html gene l(1)d.norm.-27 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032184 CG13135 http://flybase.net/reports/FBgn0032184.html protein_coding_gene CG13135 16-Dec-15 2015_12 viable FBgn0028272 l(1)G0433 lethal (1) G0433 http://flybase.net/reports/FBgn0028272.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266084 Fhos Formin homology 2 domain containing ortholog http://flybase.net/reports/FBgn0266084.html "FBgn0261259, FBgn0052030, FBgn0035925, FBgn0035927, FBgn0040229, FBgn0052025, FBgn0010755" protein_coding_gene 0003779=actin binding "0030335=positive regulation of cell migration, 0010623=developmental programmed cell death, 0051496=positive regulation of stress fiber assembly, 0035070=salivary gland histolysis, 1900026=positive regulation of substrate adhesion-dependent cell spreading, 0046716=muscle cell cellular homeostasis, 0044319=wound healing, spreading of cells, 0060439=trachea morphogenesis, 0003012=muscle system process, 0007476=imaginal disc-derived wing morphogenesis" "0005737=cytoplasm, 0005634=nucleus, 0048471=perinuclear region of cytoplasm" "l(3)01629, CG32030, Fhos, CG5775, CG42610, knittrig, desert, jaz, CG5797, dFHOS, knit, CG32025, lethal (3) 01629, jazigo" "IPR016024=Armadillo-type fold, IPR014768=Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425=Formin, FH2 domain, IPR014767=Diaphanous autoregulatory (DAD) domain" CG42610 16-Dec-15 2015_12 "ENSDARG00000063682,ENSDARG00000051768,ENSDARG00000061904" WBGene00016735(fhod-1) "ENSXETG00000017899(FHOD3),ENSXETG00000007686(FHOD1)" ENSMUSG00000034295(Fhod3) ENSG00000134775(FHOD3) FBgn0036725 CG18265 http://flybase.net/reports/FBgn0036725.html protein_coding_gene 0046872=metal ion binding ORE-10 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG18265 16-Dec-15 2015_12 "viable,fertile" DRSC10310 K -0.541188368 0.480334065 0.344347236 0.138431369 0.807926603 -1.737453188 FBgn0250755 CG42233 http://flybase.net/reports/FBgn0250755.html "FBgn0039878, FBgn0039880" protein_coding_gene "CG11574, CG2112" "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG42233 16-Dec-15 2015_12 ENSDARG00000060320(dcaf5) WBGene00011242(R11D1.1) ENSMUSG00000049106(Dcaf5) ENSG00000139990(DCAF5) FBgn0036365 cmb combover http://flybase.net/reports/FBgn0036365.html FBgn0045155 protein_coding_gene 0005515=protein binding 0035317=imaginal disc-derived wing hair organization "Combover, NEST:bs28e06, CG10732" CG10732 16-Dec-15 2015_12 viable FBgn0030266 CG11122 http://flybase.net/reports/FBgn0030266.html protein_coding_gene 0046872=metal ion binding 0005875=microtubule associated complex "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG11122 16-Dec-15 2015_12 visible "wing vein,eye" FBgn0015517 ms(2)HB223 male sterile (2) HB223 http://flybase.net/reports/FBgn0015517.html gene 16-Dec-15 2015_12 FBgn0032935 Atg18b Autophagy-related 18b http://flybase.net/reports/FBgn0032935.html protein_coding_gene "0080025=phosphatidylinositol-3,5-bisphosphate binding, 0032266=phosphatidylinositol-3-phosphate binding" "0034599=cellular response to oxidative stress, 0000045=autophagic vacuole assembly" "0034045=pre-autophagosomal structure membrane, 0005829=cytosol, 0005737=cytoplasm, 0000421=autophagic vacuole membrane" "Atg18b, Autophagy-specific gene 18b, ATG18.2, Atg18-like, CG8678, l(2)k09410, Atg18" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG8678 16-Dec-15 2015_12 YFR021W(ATG18) WBGene00018294(atg-18) ENSXETG00000003087(BC087784.1) "viable,lethal,recessive" DRSC03108 I 1.70367988 0.85034156 -0.01982464 0.269956615 0.058478325 -0.228434101 FBgn0267606 CR45944 http://flybase.net/reports/FBgn0267606.html non_protein_coding_gene CR45944 16-Dec-15 2015_12 FBgn0004436 Ubc6 Ubiquitin conjugating enzyme 6 http://flybase.net/reports/FBgn0004436.html FBgn0064873 protein_coding_gene "0002039=p53 binding, 0004842=ubiquitin-protein transferase activity" "0051297=centrosome organization, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0043066=negative regulation of apoptotic process, 0032456=endocytic recycling, 0007052=mitotic spindle organization, 0051299=centrosome separation, 0006281=DNA repair, 0000422=mitochondrion degradation" 0005634=nucleus "RAD6, Rad6, dRad6, dRAD6, UbcD6, Ubiquitin Conjugating Enzyme, BcDNA:RE56673, CG2013, Ubiquitin conjugating enzyme, Dhr6, Rad6a" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR023313=Ubiquitin-conjugating enzyme, active site, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG2013 16-Dec-15 2015_12 "ENSDARG00000071484,ENSDARG00000003017(zgc:55512),ENSDARG00000053444(ube2a),ENSDARG00000026035(zgc:100921)" YGL058W(RAD6) WBGene00006701(ubc-1) "ENSXETG00000007437(ube2a),ENSXETG00000026236(ube2b)" "ENSMUSG00000016308(Ube2a),ENSMUSG00000020390(Ube2b)" "ENSG00000077721(UBE2A),ENSG00000119048(UBE2B)" "lethal - all die before end of larval stage,recessive,neurophysiology defective,increased cell death,lethal,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,mitochondrion | third instar larval stage,wing" DRSC12370 IEK -1.746964077 -1.14141391 -1.544899447 -1.01139816 1.898146923 -0.48485935 FBgn0065561 l(2)SH0991 lethal (2) SH0991 http://flybase.net/reports/FBgn0065561.html gene l(2)SH2 0991 16-Dec-15 2015_12 "lethal,recessive" FBgn0029859 CG15892 http://flybase.net/reports/FBgn0029859.html FBgn0052918 protein_coding_gene CG32918 CG15892 16-Dec-15 2015_12 "viable,fertile" FBgn0060332 l(3)S145613 lethal (3) S145613 http://flybase.net/reports/FBgn0060332.html gene 1456/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266327 CR44992 http://flybase.net/reports/FBgn0266327.html non_protein_coding_gene CR44992 16-Dec-15 2015_12 FBgn0046639 anon-38D.6 anon-38D.6 http://flybase.net/reports/FBgn0046639.html gene 38D.6 16-Dec-15 2015_12 FBgn0000437 df defective http://flybase.net/reports/FBgn0000437.html gene 16-Dec-15 2015_12 "visible,partially lethal - majority live" "ocellar bristle,interocellar bristle" FBgn0058045 CG40045 http://flybase.net/reports/FBgn0058045.html "FBan0040045, FBgn0047074" protein_coding_gene 0004842=ubiquitin-protein transferase activity 0000209=protein polyubiquitination BcDNA:RE63412 "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site, IPR000608=Ubiquitin-conjugating enzyme E2" CG40045 16-Dec-15 2015_12 "ENSDARG00000015292(ube2g2),ENSDARG00000069527(ube2g1)" WBGene00006704(ubc-7) ENSXETG00000026172(ube2g1) ENSMUSG00000020794(Ube2g1) ENSG00000132388(UBE2G1) DRSC21232 K -0.034833707 0.168078986 0.215030145 0.277643187 0.371501906 2.233570939 FBgn0261839 pre-mod(mdg4)-Y http://flybase.net/reports/FBgn0261839.html protein_coding_gene CG42771 "IPR007588=Zinc finger, FLYWCH-type" CG42771 16-Dec-15 2015_12 FBgn0050155 tRNA:CR30155 transfer RNA:CR30155 http://flybase.net/reports/FBgn0050155.html FBgn0060010 tRNA_gene 0033416=UGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR30155, tRNA:W:CCA:AE002787-c, AE002787.trna60-TrpCCA, chr2R.trna44-TrpCCA" CR30155 16-Dec-15 2015_12 FBgn0034986 mRpS17 mitochondrial ribosomal protein S17 http://flybase.net/reports/FBgn0034986.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "MRP-S17, CG4326" "IPR000266=Ribosomal protein S17, IPR012340=Nucleic acid-binding, OB-fold" CG4326 16-Dec-15 2015_12 ENSDARG00000054164(zgc:110031) WBGene00015487(C05D11.10) ENSXETG00000010088(mrps17) ENSMUSG00000034211(Mrps17) ENSG00000154999 viable DRSC04463 E -1.234529304 0.007542804 -1.769462037 0.157535672 0.1234868 0.917702378 FBgn0043527 anon-AE003814.3 anon-AE003814.3 http://flybase.net/reports/FBgn0043527.html gene unnamed 16-Dec-15 2015_12 FBgn0015302 Su(SD)3A Suppressor of SD 3A http://flybase.net/reports/FBgn0015302.html gene 16-Dec-15 2015_12 FBgn0261452 scaRNA:MeU2-G25 small Cajal body-specific RNA : MeU2-G25 http://flybase.net/reports/FBgn0261452.html snoRNA_gene 0015030=Cajal body "scaRNA:mgU2-25, scaRNA:mask-a, mgU2-25" CR43569 16-Dec-15 2015_12 FBgn0011642 Zyx Zyxin http://flybase.net/reports/FBgn0011642.html "FBgn0047225, FBgn0052018" protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding" "0035329=hippo signaling, 0007430=terminal branching, open tracheal system, 0007593=chitin-based cuticle sclerotization, 0045572=positive regulation of imaginal disc growth, 0048526=imaginal disc-derived wing expansion, 0007155=cell adhesion, 0035002=liquid clearance, open tracheal system, 0045805=positive regulation of eclosion" "0005925=focal adhesion, 0001725=stress fiber, 0005911=cell-cell junction, 0035003=subapical complex, 0005856=cytoskeleton" "BcDNA:LD06023, ZYX102, Zyx102, lim, zyxin, Lim102EF, zyx102, CG32018, Zyx, Zyx102EF, zyx, DmLIM-1, DLim-1, Zyxin, unnamed" "IPR001781=Zinc finger, LIM-type" CG32018 16-Dec-15 2015_12 WBGene00006999(zyx-1) ENSXETG00000012850(LPP) ENSMUSG00000033306(Lpp) "ENSG00000145012(LPP),ENSG00000087077(TRIP6)" "viable,locomotor behavior defective,eclosion defective,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,size defective" "wing,adult abdomen,adult cuticle,adult trachea,tracheole,crossvein,ectopic" FBgn0033307 CG14752 http://flybase.net/reports/FBgn0033307.html protein_coding_gene CG14752 16-Dec-15 2015_12 viable FBgn0051395 CG31395 http://flybase.net/reports/FBgn0051395.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040690 CG13899 http://flybase.net/reports/FBgn0040690.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039451 CG6420 http://flybase.net/reports/FBgn0039451.html protein_coding_gene "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG6420 16-Dec-15 2015_12 ENSDARG00000006585 WBGene00007428(C08B6.7) ENSXETG00000010253(wdr20) "ENSMUSG00000035560(Wdr20b),ENSMUSG00000037957(Wdr20a),ENSMUSG00000030410(Dmwd)" "ENSG00000185800(DMWD),ENSG00000140153(WDR20)" "viable,fertile" DRSC16035 K -0.39426711 0.241122906 -0.656145642 0.678835876 2.117854079 0.720366585 FBgn0012041 Atn Allatotropin http://flybase.net/reports/FBgn0012041.html gene 0005179=hormone activity 16-Dec-15 2015_12 FBgn0051211 CG31211 http://flybase.net/reports/FBgn0051211.html "FBgn0037965, FBgn0037966, FBgn0067793" protein_coding_gene "CG18546, cDNA, CG14732, anon-WO03070958.3" CG31211 16-Dec-15 2015_12 ENSDARG00000069855(srsf18) WBGene00013177(rsy-1) ENSXETG00000000800(Q6DDD0_XENTR) ENSMUSG00000028248(Srsf18) viable FBgn0030475 CG15748 http://flybase.net/reports/FBgn0030475.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001446 l(1)7Ch lethal (1) 7Ch http://flybase.net/reports/FBgn0001446.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267508 28SrRNA-ë¬:CR45848 28S ribosomal RNA pseudogene:CR45848 http://flybase.net/reports/FBgn0267508.html pseudogene_attribute CR45848 CR45848 16-Dec-15 2015_12 FBgn0082959 snoRNA:ë¬28S-3405b snoRNA:ë¬28S-3405b http://flybase.net/reports/FBgn0082959.html snoRNA_gene "psi28s-3405b, CR34620" CR34620 16-Dec-15 2015_12 FBgn0052250 PMP34 Peroxisomal Membrane Protein 34 http://flybase.net/reports/FBgn0052250.html "FBgn0035531, FBgn0064886" protein_coding_gene "0005215=transporter activity, 0022857=transmembrane transporter activity" "0006839=mitochondrial transport, 0006810=transport" "0005779=integral component of peroxisomal membrane, 0005778=peroxisomal membrane, 0031966=mitochondrial membrane" "BcDNA:RE36975, CG1326, CG32250, dPMP34" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG32250 16-Dec-15 2015_12 ENSDARG00000061684(zgc:162641) ENSXETG00000022968(slc25a17) ENSMUSG00000022404(Slc25a17) ENSG00000100372(SLC25A17) viable FBgn0001189 hfw halfway http://flybase.net/reports/FBgn0001189.html FBgn0023532 protein_coding_gene "0035556=intracellular signal transduction, 0035073=pupariation, 0035075=response to ecdysone" "singed wings, CT10406, CG3095, SWI, singed-wings, swi, l(1)2Bf, l(1)nfw, EG:171E4.2" IPR001611=Leucine-rich repeat CG3095 16-Dec-15 2015_12 "viable,reduced,visible,recessive,lethal,male,lethal - all die before end of pupal stage,some die during pupal stage" "wing,adult abdomen" FBgn0024860 l(3)96Bb lethal (3) 96Bb http://flybase.net/reports/FBgn0024860.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034643 CG10321 http://flybase.net/reports/FBgn0034643.html protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG10321 16-Dec-15 2015_12 WBGene00016713(C46E10.9) viable FBgn0021811 l(2)k16525 lethal (2) k16525 http://flybase.net/reports/FBgn0021811.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039210 CG13625 http://flybase.net/reports/FBgn0039210.html FBgn0062057 protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" 0071013=catalytic step 2 spliceosome anon-WO0118547.376 IPR018609=Bud13 CG13625 16-Dec-15 2015_12 ENSDARG00000006666(si:dkeyp-69c1.6) WBGene00011142(R08D7.1) ENSXETG00000003767(BUD13) ENSMUSG00000032077(Bud13) ENSG00000137656(BUD13) FBgn0005172 l(2)G583 lethal (2) G583 http://flybase.net/reports/FBgn0005172.html gene 16-Dec-15 2015_12 lethal FBgn0037018 CG4042 http://flybase.net/reports/FBgn0037018.html protein_coding_gene IPR026303=ATP synthase subunit s-like protein CG4042 16-Dec-15 2015_12 WBGene00021815(Y53G8AR.8) ENSXETG00000018760(ATP5SL) ENSMUSG00000057229(Atp5sl) ENSG00000105341(ATP5SL) viable FBgn0032312 CG14071 http://flybase.net/reports/FBgn0032312.html protein_coding_gene 0051726=regulation of cell cycle CG14071 16-Dec-15 2015_12 viable FBgn0002848 msg missing http://flybase.net/reports/FBgn0002848.html gene ms 16-Dec-15 2015_12 "visible,female sterile,male fertile,poor" macrochaeta FBgn0000798 fs(1)de9 female sterile (1) defective eggs 9 http://flybase.net/reports/FBgn0000798.html gene de9 16-Dec-15 2015_12 female sterile "endochorion,dorsal appendage,chorion" FBgn0004097 l(2)60De lethal (2) 60De http://flybase.net/reports/FBgn0004097.html gene 16-Dec-15 2015_12 "lethal,recessive,visible" FBgn0026740 anon-64Ca anon-64Ca http://flybase.net/reports/FBgn0026740.html gene gene b 16-Dec-15 2015_12 FBgn0011043 l(1)Stark-b lethal (1) of Stark b http://flybase.net/reports/FBgn0011043.html FBgn0010212 gene "l(1)Sb, lethal (1) Sb" 16-Dec-15 2015_12 lethal FBgn0260047 33AC1 http://flybase.net/reports/FBgn0260047.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0065204 l(2)SH2285 lethal (2) SH2285 http://flybase.net/reports/FBgn0065204.html gene l(2)SH2 2285 16-Dec-15 2015_12 "lethal,recessive" FBgn0034883 CG17664 http://flybase.net/reports/FBgn0034883.html protein_coding_gene "0015267=channel activity, 0015250=water channel activity" "0003014=renal system process, 0055085=transmembrane transport" 0016021=integral component of membrane Aqp17664 "IPR022357=Major intrinsic protein, conserved site, IPR023271=Aquaporin-like, IPR000425=Major intrinsic protein" CG17664 16-Dec-15 2015_12 YPR192W(AQY1) "WBGene00000172(aqp-4),WBGene00000174(aqp-6),WBGene00000173(aqp-5)" "viable,visible,lethal" trichogen cell FBgn0262189 mir-2500 mir-2500 stem loop http://flybase.net/reports/FBgn0262189.html miRNA_gene "CR42896, dme-mir-2500" CR42896 16-Dec-15 2015_12 viable FBgn0014848 Eig71Eh Eig71Eh http://flybase.net/reports/FBgn0014848.html protein_coding_gene "0042742=defense response to bacterium, 0007552=metamorphosis" 0005576=extracellular region "CG7594, L71-8, L71, EIG71-H" IPR003475=Insect protein of unknown function CG7594 16-Dec-15 2015_12 viable FBgn0001294 jyx jaunty-x http://flybase.net/reports/FBgn0001294.html gene jauntex 16-Dec-15 2015_12 "viable,reduced,visible" FBgn0266247 CR44942 http://flybase.net/reports/FBgn0266247.html non_protein_coding_gene lincRNA.759 CR44942 16-Dec-15 2015_12 FBgn0259653 B0538 http://flybase.net/reports/FBgn0259653.html gene 16-Dec-15 2015_12 visible "wing,wing sensillum,ectopic,wing margin bristle,leg,distal" FBgn0025490 l(3)82EFa lethal (3) 82EFa http://flybase.net/reports/FBgn0025490.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035871 BI-1 Bax Inhibitor-1 http://flybase.net/reports/FBgn0035871.html protein_coding_gene "0035071=salivary gland cell autophagic cell death, 0009267=cellular response to starvation, 0060548=negative regulation of cell death, 0043066=negative regulation of apoptotic process, 1900102=negative regulation of endoplasmic reticulum unfolded protein response, 0010507=negative regulation of autophagy, 0060702=negative regulation of endoribonuclease activity" "0016021=integral component of membrane, 0043234=protein complex" "Bax inhibitor-1, CG7188, dTmbim6, dBI-1, d-BI-1" "IPR006213=Bax inhibitor 1, conserved site, IPR006214=Bax inhibitor 1-related" CG7188 16-Dec-15 2015_12 ENSXETG00000009777(tegt) ENSMUSG00000023010(Tmbim6) ENSG00000139644(TMBIM6) "viable,fertile,starvation stress response defective,long lived,nutrition conditional,short lived,chemical conditional" "embryonic/larval salivary gland | pupal stage,lysosome | nutrition conditionalda.G32,fat body,nutrition conditional,autophagic vacuole | nutrition conditionalda.G32" FBgn0053408 5SrRNA:CR33408 5SrRNA:CR33408 http://flybase.net/reports/FBgn0053408.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33408 CR33408 16-Dec-15 2015_12 FBgn0041589 l(3)S136802 lethal (3) S136802 http://flybase.net/reports/FBgn0041589.html gene 1368.02 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" presumptive embryonic/larval nervous system FBgn0028973 yew yew http://flybase.net/reports/FBgn0028973.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 "dendrite | dorsal | embryonic stage,presumptive embryonic/larval peripheral nervous system,dorsal" FBgn0067787 anon-i118 anon-i118 http://flybase.net/reports/FBgn0067787.html gene i118 16-Dec-15 2015_12 FBgn0053767 CG33767 http://flybase.net/reports/FBgn0053767.html FBgn0037173 protein_coding_gene CG14458 "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG33767 16-Dec-15 2015_12 FBgn0024734 PRL-1 PRL-1 phosphatase http://flybase.net/reports/FBgn0024734.html "FBgn0027875, FBgn0062445" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0004727=prenylated protein tyrosine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity" "0035335=peptidyl-tyrosine dephosphorylation, 0006470=protein dephosphorylation" "0005886=plasma membrane, 0005737=cytoplasm" "PRL1, BG:DS07473.3, CG4993, BcDNA:RE40268, PrL-1, dPRL-1, PRL-1, PRL" "IPR000387=Tyrosine specific protein phosphatases domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR029021=Protein-tyrosine phosphatase-like" CG4993 16-Dec-15 2015_12 "ENSDARG00000006242(ptp4a1),ENSDARG00000035676(zgc:101724),ENSDARG00000038087,ENSDARG00000054814(wu:fc14a08),ENSDARG00000039997(ptp4a3)" WBGene00004184(prl-1) "ENSXETG00000004454(ptp4a1),ENSXETG00000005239(ptp4a2),ENSXETG00000023744(PTP4A3)" "ENSMUSG00000026064(Ptp4a1),ENSMUSG00000028788(Ptp4a2),ENSMUSG00000059895(Ptp4a3)" "ENSG00000112245(PTP4A1),ENSG00000184007(PTP4A2),ENSG00000184489(PTP4A3)" "viable,fertile,size defective,somatic clone,hypoplasia,lethal - all die before end of larval stage,majority die during first instar larval stage,wild-type,partially lethal - majority die,recessive" "wing,eye,somatic clone,head capsule,wing disc" DRSC27332 IK 3.596079543 0.235626341 0.769394229 0.342403053 0.316581321 1.766985396 FBgn0067360 l(2)NC83 lethal (2) NC83 http://flybase.net/reports/FBgn0067360.html gene NC83 16-Dec-15 2015_12 "lethal,recessive" FBgn0070036 3R-69-15 3R-69-15 http://flybase.net/reports/FBgn0070036.html gene 0007310=oocyte dorsal/ventral axis specification 16-Dec-15 2015_12 "egg,germline clone,maternal effect,dorsal appendage,non-rescuable maternal effect" FBgn0067060 P307 P307 http://flybase.net/reports/FBgn0067060.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0013636 l(4)ry1 lethal (4) ry1 http://flybase.net/reports/FBgn0013636.html gene "unnamed, l(4)1" 16-Dec-15 2015_12 lethal FBgn0045971 PdL75A3 PdL75A3 http://flybase.net/reports/FBgn0045971.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265178 CG44243 http://flybase.net/reports/FBgn0265178.html FBgn0034089 protein_coding_gene 0017118=lipoyltransferase activity 0009249=protein lipoylation CG8446 "IPR004143=Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain" CG44243 16-Dec-15 2015_12 FBgn0060978 l(3)S028705b lethal (3) S028705b http://flybase.net/reports/FBgn0060978.html gene 0287/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0065281 l(2)SH2031 lethal (2) SH2031 http://flybase.net/reports/FBgn0065281.html gene l(2)SH2 2031 16-Dec-15 2015_12 "lethal,recessive" FBgn0265733 CR44540 http://flybase.net/reports/FBgn0265733.html non_protein_coding_gene CR44540 16-Dec-15 2015_12 FBgn0035470 Ccz1 Ccz1 ortholog http://flybase.net/reports/FBgn0035470.html protein_coding_gene 0005085=guanyl-nucleotide exchange factor activity "0032510=endosome to lysosome transport via multivesicular body sorting pathway, 0006914=autophagy" "0005829=cytosol, 0035658=Mon1-Ccz1 complex" "NP_647835, CG14980, C7orf28B, Dccz1" "IPR013176=Protein of unknown function DUF1712, fungi" CG14980 16-Dec-15 2015_12 ENSDARG00000056559(zgc:55344) WBGene00010283(ccz-1) ENSXETG00000024053(TGas077n04.1) ENSMUSG00000029617(AU022870) "ENSG00000146574(C7orf28B),ENSG00000122674(CCZ1)" "viable,fertile" endosomeptc-559.1 FBgn0029685 CG2938 http://flybase.net/reports/FBgn0029685.html protein_coding_gene 0046331=lateral inhibition "IPR026057=PC-Esterase, IPR012419=Cas1p 10 TM acyl transferase domain" CG2938 16-Dec-15 2015_12 ENSDARG00000023900(casd1) ENSXETG00000020309(CASD1) ENSMUSG00000015189(Casd1) ENSG00000127995(CASD1) "viable,visible,body color defective" "chaeta,mesothoracic tergum" FBgn0023181 Orc4 Origin recognition complex subunit 4 http://flybase.net/reports/FBgn0023181.html protein_coding_gene 0003677=DNA binding 0006270=DNA replication initiation 0005664=nuclear origin of replication recognition complex "orc4, DmORC4, rDmORC, ORC4, ORC, dmOrc4, CG2917" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR016527=Origin recognition complex, subunit 4, IPR003593=AAA+ ATPase domain" CG2917 16-Dec-15 2015_12 YPR162C(ORC4) ENSXETG00000021718(orc4l) ENSMUSG00000026761(Orc4l) ENSG00000115947(ORC4) embryonic stage && larval stage "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0015928 dfc defaced http://flybase.net/reports/FBgn0015928.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" "mouth hooks,lateral process,dorsal bridge" FBgn0267577 CR45917 http://flybase.net/reports/FBgn0267577.html non_protein_coding_gene pri-mir-92b CR45917 16-Dec-15 2015_12 FBgn0032422 atilla atilla http://flybase.net/reports/FBgn0032422.html protein_coding_gene "atilla, CG6579" CG6579 16-Dec-15 2015_12 "viable,fertile" FBgn0000627 Eyl Eyeluf http://flybase.net/reports/FBgn0000627.html gene 16-Dec-15 2015_12 visible "eye,antenna" FBgn0035155 RabX6 RabX6 http://flybase.net/reports/FBgn0035155.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport" "0031982=vesicle, 0043025=neuronal cell body" "CG12015, DmRabX6, rabx6, rabX6" "IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12015 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0030944 CG6617 http://flybase.net/reports/FBgn0030944.html FBgn0027737 protein_coding_gene anon-EST:Posey180 "IPR013144=CRA domain, IPR006595=CTLH, C-terminal LisH motif, IPR024964=CTLH/CRA C-terminal to LisH motif domain, IPR006594=LIS1 homology motif" CG6617 16-Dec-15 2015_12 "ENSDARG00000037589(c20orf11),ENSDARG00000022768(zgc:73100)" ENSXETG00000006105(C20orf11) ENSMUSG00000027573(2310003C23Rik) ENSG00000101193(C20orf11) FBgn0060433 l(3)S125414b lethal (3) S125414b http://flybase.net/reports/FBgn0060433.html gene 1254/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0265993 CR44768 http://flybase.net/reports/FBgn0265993.html non_protein_coding_gene lincRNA.186 CR44768 16-Dec-15 2015_12 FBgn0001747 l(1)HM19 lethal (1) HM19 http://flybase.net/reports/FBgn0001747.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive" FBgn0025809 Paf-AHë± Platelet-activating factor acetylhydrolase alpha http://flybase.net/reports/FBgn0025809.html protein_coding_gene 0003847=1-alkyl-2-acetylglycerophosphocholine esterase activity "PAFAHalpha, platelet-activating factor acetylhydrolase alpha subunit homolog, Paf-AHalpha, CG8962, Dmaalpha[[PAFAH]], AAC83820, platelet-activating factor acetylhydrolase Ib alpha-subunit homolog" IPR013830=SGNH hydrolase-type esterase domain CG8962 16-Dec-15 2015_12 "ENSDARG00000058047(pafah1b3),ENSDARG00000035352(pafah1b2)" "ENSXETG00000003761(PAFAH1B2),ENSXETG00000012063(Q6DIU3_XENTR)" "ENSMUSG00000003131(Pafah1b2),ENSMUSG00000005447(Pafah1b3)" "ENSG00000168092(PAFAH1B2),ENSG00000079462(PAFAH1B3)" viable FBgn0003877 tu(2)48j tumor(2)48j http://flybase.net/reports/FBgn0003877.html gene tu-48j 16-Dec-15 2015_12 melanotic mass phenotype FBgn0028407 Drep3 DNA fragmentation factor-related protein 3 http://flybase.net/reports/FBgn0028407.html "FBgn0033678, FBgn0063749" protein_coding_gene "0006915=apoptotic process, 0022008=neurogenesis" 0005622=intracellular "drep-3, BcDNA:AT08574, drep3, Drep-3, DREP-3, Drep3, Rep3, CG8364, CG13187" IPR003508=CIDE-N domain CG8364 16-Dec-15 2015_12 "ENSMUSG00000030278(Cidec),ENSMUSG00000024526(Cidea),ENSMUSG00000022219(Cideb)" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0261629 CG42712 http://flybase.net/reports/FBgn0261629.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029893 CG14442 http://flybase.net/reports/FBgn0029893.html protein_coding_gene CG14442 16-Dec-15 2015_12 "viable,fertile,visible" mesothoracic tergum FBgn0013434 btd::Mmmm\Sp1 Sp1 http://flybase.net/reports/FBgn0013434.html engineered_fusion_gene btd::mammal\Sp1 16-Dec-15 2015_12 FBgn0265799 CR44588 http://flybase.net/reports/FBgn0265799.html non_protein_coding_gene CR44588 16-Dec-15 2015_12 FBgn0069417 JJF137 JJF137 http://flybase.net/reports/FBgn0069417.html gene 16-Dec-15 2015_12 stress response defective FBgn0264392 CR43840 http://flybase.net/reports/FBgn0264392.html non_protein_coding_gene CR43840 16-Dec-15 2015_12 FBgn0053435 5SrRNA:CR33435 5SrRNA:CR33435 http://flybase.net/reports/FBgn0053435.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33435 CR33435 16-Dec-15 2015_12 FBgn0016058 rtg rotated genitalia http://flybase.net/reports/FBgn0016058.html gene 16-Dec-15 2015_12 visible genitalia FBgn0264605 CG43954 http://flybase.net/reports/FBgn0264605.html protein_coding_gene 0016021=integral component of membrane CG43954 16-Dec-15 2015_12 FBgn0265493 BG01887 http://flybase.net/reports/FBgn0265493.html gene 16-Dec-15 2015_12 FBgn0262227 mir-991 mir-991 stem loop http://flybase.net/reports/FBgn0262227.html miRNA_gene "miR-991, CR42934, dme-mir-991" CR42934 16-Dec-15 2015_12 lethal FBgn0052485 CG32485 http://flybase.net/reports/FBgn0052485.html FBgn0035391 protein_coding_gene CG2159 "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain" CG32485 16-Dec-15 2015_12 "WBGene00011404(T03F7.7),WBGene00007925(C34C12.6)" viable FBgn0259918 inaF-B inaF-B http://flybase.net/reports/FBgn0259918.html FBgn0023077 protein_coding_gene "0005515=protein binding, 0005246=calcium channel regulator activity" "0016057=regulation of membrane potential in photoreceptor cell, 0009416=response to light stimulus" "0033583=rhabdomere membrane, 0016028=rhabdomere, 0016027=inaD signaling complex" "inaF, INAF, INAF-B, CG42447, InaF" "IPR029162=TRP-interacting helix, InaF motif" CG42447 16-Dec-15 2015_12 neurophysiology defective photoreceptor cell FBgn0262908 sax::Agam\sax http://flybase.net/reports/FBgn0262908.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0001434 l(1)7Ad lethal (1) 7Ad http://flybase.net/reports/FBgn0001434.html gene "l(1)jnR4, jnR4" 16-Dec-15 2015_12 "lethal,recessive" "genitalia,male,wing,wing disc,mesothoracic leg disc" FBgn0035247 metl methyltransferase-like http://flybase.net/reports/FBgn0035247.html FBgn0027767 protein_coding_gene 0008757=S-adenosylmethionine-dependent methyltransferase activity "CG13929, anon-EST:Posey109" "IPR026113=Methyltransferase-like, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG13929 16-Dec-15 2015_12 "ENSDARG00000008105(mettl2a),ENSDARG00000070225,ENSDARG00000017359(mettl8)" WBGene00044720(Y53F4B.42) ENSXETG00000007856(Q5M8E6_XENTR) "ENSMUSG00000020691(Mettl2),ENSMUSG00000041975(Mettl8)" "ENSG00000165055(METTL2B),ENSG00000087995(METTL2A),ENSG00000123600(METTL8)" "wild-type,viable" FBgn0051438 CheB93b Chemosensory protein B 93b http://flybase.net/reports/FBgn0051438.html protein_coding_gene 0008289=lipid binding "0007606=sensory perception of chemical stimulus, 0043695=detection of pheromone" "0005615=extracellular space, 0005576=extracellular region" "CG31438, CheB93b" CG31438 16-Dec-15 2015_12 viable FBgn0062442 Cisd2 CDGSH iron sulfur domain 2 http://flybase.net/reports/FBgn0062442.html FBgn0039653 protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding" 0043231=intracellular membrane-bounded organelle "MitoNEET, BcDNA:RE49709, cisd2, dWFS2, CG1458" "IPR018967=Iron sulphur-containing domain, CDGSH-type, IPR006622=Iron sulphur-containing domain, CDGSH-type, subfamily, IPR019610=Iron sulphur domain-containing, mitoNEET, N-terminal" CG1458 16-Dec-15 2015_12 ENSDARG00000052703(cisd2) ENSXETG00000005114(Q6GLC0_XENTR) ENSMUSG00000028165(Cisd2) ENSG00000145354(CISD2) viable FBgn0266210 CR44905 http://flybase.net/reports/FBgn0266210.html non_protein_coding_gene CR44905 16-Dec-15 2015_12 FBgn0041756 eth-as314 eth-as314 http://flybase.net/reports/FBgn0041756.html gene eth[as]314 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0028391 anon-50ABc anon-50ABc http://flybase.net/reports/FBgn0028391.html gene C 16-Dec-15 2015_12 FBgn0027182 l(2)60A-L lethal (2) 60A-L http://flybase.net/reports/FBgn0027182.html gene 16-Dec-15 2015_12 lethal FBgn0053178 CG33178 http://flybase.net/reports/FBgn0053178.html "FBgn0030609, FBgn0047036" protein_coding_gene "BcDNA:RH14671, CG5579" "IPR023352=Membrane associated eicosanoid/glutathione metabolism-like domain, IPR001129=Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein" CG33178 16-Dec-15 2015_12 "ENSDARG00000032618(mgst1),ENSDARG00000022165(zgc:92357)" ENSXETG00000014173(PTGES) ENSMUSG00000008540(Mgst1) ENSG00000008394(MGST1) viable FBgn0013269 FK506-bp1 FK506-binding protein 1 http://flybase.net/reports/FBgn0013269.html protein_coding_gene "0070594=juvenile hormone response element binding, 0003755=peptidyl-prolyl cis-trans isomerase activity, 0005515=protein binding, 0005528=FK506 binding" "0016242=negative regulation of macroautophagy, 0000412=histone peptidyl-prolyl isomerization, 0035626=juvenile hormone mediated signaling pathway, 0010507=negative regulation of autophagy, 0018208=peptidyl-proline modification, 0006457=protein folding" "0005875=microtubule associated complex, 0016020=membrane, 0005730=nucleolus, 0005634=nucleus" "FKBP39, IFK506-bp1, CG6226, FK506-binding protein of 39 kDa, FK506bp1, FKbp39" "IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR026257=FK506-binding protein" CG6226 16-Dec-15 2015_12 "YML074C(FPR3),YLR449W(FPR4)" "WBGene00001428(fkb-3),WBGene00001430(fkb-5),WBGene00001429(fkb-4)" " embryonic stage -- adult stage , adult stage && oogenesis stage , adult stage " " ovary

,

ubiquitous " "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "embryonic/larval fat body,somatic clone,trichogen cell,mesothoracic tergum" DRSC16667 EK 1.201663215 0.791282378 1.69799848 -0.397210135 2.584880987 0.550019966 FBgn0266619 CR45126 http://flybase.net/reports/FBgn0266619.html non_protein_coding_gene CR45126 16-Dec-15 2015_12 FBgn0264678 CR43963 http://flybase.net/reports/FBgn0264678.html non_protein_coding_gene CR43963 16-Dec-15 2015_12 FBgn0065647 l(2)SH0749 lethal (2) SH0749 http://flybase.net/reports/FBgn0065647.html gene l(2)SH2 0749 16-Dec-15 2015_12 "lethal,recessive" FBgn0069912 CR40474 http://flybase.net/reports/FBgn0069912.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0005191 l(2)S51 lethal of Seto 51 http://flybase.net/reports/FBgn0005191.html gene 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0020932 Est-B Est-B http://flybase.net/reports/FBgn0020932.html gene 0052689=carboxylic ester hydrolase activity 16-Dec-15 2015_12 FBgn0000023 acclinal-wing acclinal wing http://flybase.net/reports/FBgn0000023.html gene acc 16-Dec-15 2015_12 "visible,recessive,viable,good,fertile,flightless" wing FBgn0041129 l(2)45Ag lethal (2) 45Ag http://flybase.net/reports/FBgn0041129.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259710 CG42364 http://flybase.net/reports/FBgn0259710.html "FBgn0034648, FBan0015675" protein_coding_gene CG15675 CG42364 16-Dec-15 2015_12 FBgn0052212 CG32212 http://flybase.net/reports/FBgn0052212.html protein_coding_gene CG32212 16-Dec-15 2015_12 FBgn0060980 l(3)S028401 lethal (3) S028401 http://flybase.net/reports/FBgn0060980.html gene 0284/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0001828 l(1)TS56 lethal (1) TS56 http://flybase.net/reports/FBgn0001828.html gene l(1)TS-56 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval tracheal system,embryonic segment" FBgn0025616 CG13359 http://flybase.net/reports/FBgn0025616.html protein_coding_gene EG:34F3.9 CG13359 16-Dec-15 2015_12 viable FBgn0031940 CG7214 http://flybase.net/reports/FBgn0031940.html protein_coding_gene 0051533=positive regulation of NFAT protein import into nucleus CG7214 16-Dec-15 2015_12 "viable,fertile" DRSC03028 IEK 1.479609521 -2.499599158 1.555861842 1.444557231 1.885904257 0.032893018 FBgn0015766 Msr-110 Msr-110 http://flybase.net/reports/FBgn0015766.html protein_coding_gene 0016021=integral component of membrane "Engrailed nuclear homeoprotein-regulated gene, CG10596" IPR022207=Genetic suppressor element-like CG10596 16-Dec-15 2015_12 " embryonic stage | stage 11 , embryonic stage | stage 11 | late , embryonic stage | 12-18 hr , embryonic stage | stage 11 | early , larval stage " " embryonic/larval pharynx

, inclusive hindgut primordium

, median tooth

, posterior spiracle primordium

, anal pad | presumptive

, stomodeum

, antenno-maxillary complex | presumptive

, imaginal disc

, epidermis

" viable FBgn0037412 Osi4 Osiris 4 http://flybase.net/reports/FBgn0037412.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG10303" IPR012464=Protein of unknown function DUF1676 CG10303 16-Dec-15 2015_12 viable FBgn0023530 CG3740 http://flybase.net/reports/FBgn0023530.html protein_coding_gene 0050905=neuromuscular process EG:171E4.4 CG3740 16-Dec-15 2015_12 "ENSDARG00000058857,ENSDARG00000018532(zgc:101715),ENSDARG00000068408" ENSXETG00000010474(Q6DJ35_XENTR) ENSMUSG00000054676(1600014C10Rik) ENSG00000131943(C19orf12) viable FBgn0058317 CG40317 http://flybase.net/reports/FBgn0058317.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263355 CG31688 http://flybase.net/reports/FBgn0263355.html "FBgn0040998, FBgn0051688, FBgn0032861, FBgn0032862, FBgn0040999" protein_coding_gene "CG18597, 38C.49, CG11016, 38C.52, CG11017, CG31688-PA, CG11019" IPR001602=Uncharacterised protein family UPF0047 CG31688 16-Dec-15 2015_12 FBgn0266008 CR44781 http://flybase.net/reports/FBgn0266008.html non_protein_coding_gene CR44781 16-Dec-15 2015_12 FBgn0020858 fj-s four-jointed-similis http://flybase.net/reports/FBgn0020858.html gene 16-Dec-15 2015_12 FBgn0267120 CR45560 http://flybase.net/reports/FBgn0267120.html non_protein_coding_gene CR45560 16-Dec-15 2015_12 FBgn0024509 Sec13 Sec13 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0024509.html "FBgn0025715, FBgn0027897" protein_coding_gene 0005198=structural molecule activity "0007184=SMAD protein import into nucleus, 0006607=NLS-bearing protein import into nucleus, 0006900=membrane budding, 0035293=chitin-based larval cuticle pattern formation, 0010629=negative regulation of gene expression, 0008363=larval chitin-based cuticle development, 0090114=COPII-coated vesicle budding" "0031080=nuclear pore outer ring, 0030127=COPII vesicle coat, 0035859=Seh1-associated complex" "sec13, CG6773, l(3)01031, BEST:CK00043, CK00043, Dsec13, BcDNA:LD03471, SEC13, Sec13" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG6773 16-Dec-15 2015_12 ENSDARG00000054807(sec13) YLR208W(SEC13) WBGene00003806(npp-20) ENSXETG00000001453(sec13l1) ENSMUSG00000030298(Sec13) ENSG00000157020(SEC13) "lethal,recessive" FBgn0024623 l(4)102Ca lethal (4) 102Ca http://flybase.net/reports/FBgn0024623.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060929 l(3)S042016b lethal (3) S042016b http://flybase.net/reports/FBgn0060929.html gene 0420/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0265870 CR44659 http://flybase.net/reports/FBgn0265870.html non_protein_coding_gene CR44659 16-Dec-15 2015_12 FBgn0026727 chs chaos http://flybase.net/reports/FBgn0026727.html gene 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,commissure,longitudinal connective" FBgn0036470 CG13463 http://flybase.net/reports/FBgn0036470.html FBgn0063065 protein_coding_gene BcDNA:RE10167 CG13463 16-Dec-15 2015_12 "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011048 l(1)Q1 lethal (1) Q1 http://flybase.net/reports/FBgn0011048.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0050197 CG30197 http://flybase.net/reports/FBgn0050197.html FBgn0063075 protein_coding_gene 0030414=peptidase inhibitor activity 0005576=extracellular region BcDNA:RE05231 IPR008197=WAP-type 'four-disulfide core' domain CG30197 16-Dec-15 2015_12 viable FBgn0004038 yea4 yeast 4 http://flybase.net/reports/FBgn0004038.html gene 16-Dec-15 2015_12 FBgn0003335 Scn Scutenick http://flybase.net/reports/FBgn0003335.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "scutellar bristle,ocellus,macrochaeta,eye,cold sensitive,scutellum" FBgn0036230 CG11570 http://flybase.net/reports/FBgn0036230.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region mlncRNA68E3 IPR002557=Chitin binding domain CG11570 16-Dec-15 2015_12 "viable,fertile" FBgn0026161 tiz tiziano http://flybase.net/reports/FBgn0026161.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 FBgn0037815 Rrp46 Rrp46 http://flybase.net/reports/FBgn0037815.html protein_coding_gene 0000175=3'-5'-exoribonuclease activity "0010468=regulation of gene expression, 0006397=mRNA processing" "0005737=cytoplasm, 0000177=cytoplasmic exosome (RNase complex), 0000176=nuclear exosome (RNase complex)" "CG4043, dRrp46, rrp46" "IPR020568=Ribosomal protein S5 domain 2-type fold, IPR027408=PNPase/RNase PH domain, IPR001247=Exoribonuclease, phosphorolytic domain 1, IPR015847=Exoribonuclease, phosphorolytic domain 2" CG4043 16-Dec-15 2015_12 ENSDARG00000040557(exosc5) YGR095C(RRP46) WBGene00000798(crn-5) ENSXETG00000018752(EXOSC5) ENSMUSG00000061286(Exosc5) ENSG00000077348(EXOSC5) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0015441 l(1)6DEa lethal (1) 6DEa http://flybase.net/reports/FBgn0015441.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037099 CG7173 http://flybase.net/reports/FBgn0037099.html protein_coding_gene IPR002350=Kazal domain CG7173 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000778 fs(1)A1371 female sterile (1) A1371 http://flybase.net/reports/FBgn0000778.html gene fs(1)1371 16-Dec-15 2015_12 "lethal,maternal effect,female sterile,recessive,heat sensitive,non-rescuable maternal effect" "blastoderm embryo,gastrula embryo" FBgn0015932 dsRNABP6 ds-RNA binding protein 6 http://flybase.net/reports/FBgn0015932.html gene 0003725=double-stranded RNA binding dsRNABP#6 16-Dec-15 2015_12 FBgn0259335 EP-M89 http://flybase.net/reports/FBgn0259335.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,wing,chaeta" FBgn0060338 l(3)S144507a lethal (3) S144507a http://flybase.net/reports/FBgn0060338.html gene 1445/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0262126 Sec24CD Sec24CD ortholog (H. sapiens) http://flybase.net/reports/FBgn0262126.html "FBgn0001106, FBgn0261643, FBgn0086717, FBgn0031408, FBgn0046217" protein_coding_gene "0005215=transporter activity, 0005048=signal sequence binding, 0008270=zinc ion binding" "0008360=regulation of cell shape, 0007030=Golgi organization, 0072661=protein targeting to plasma membrane, 0009306=protein secretion, 0040003=chitin-based cuticle development, 0007029=endoplasmic reticulum organization, 0022409=positive regulation of cell-cell adhesion, 0035149=lumen formation, open tracheal system, 0090110=cargo loading into COPII-coated vesicle, 0071711=basement membrane organization, 0034394=protein localization to cell surface, 0035158=regulation of tube diameter, open tracheal system, 0016203=muscle attachment, 0048081=positive regulation of cuticle pigmentation, 0035151=regulation of tube size, open tracheal system, 0000902=cell morphogenesis, 0030011=maintenance of cell polarity, 0003331=positive regulation of extracellular matrix constituent secretion" "0005811=lipid particle, 0030127=COPII vesicle coat, 0070971=endoplasmic reticulum exit site" "Ghost, CG10882, sten, Sten, Sec24, FBgn0031408, stenosis, BcDNA:LP05220, sec24, ghost, gho, Sec24CD, sfb3" "IPR006896=Sec23/Sec24, trunk domain, IPR006895=Zinc finger, Sec23/Sec24-type, IPR012990=Sec23/Sec24 beta-sandwich, IPR029006=ADF-H/Gelsolin-like domain, IPR007123=Gelsolin-like domain, IPR002035=von Willebrand factor, type A, IPR006900=Sec23/Sec24, helical domain" CG10882 16-Dec-15 2015_12 ENSDARG00000060575 WBGene00004755(sec-24.1) ENSXETG00000010012(TEgg056m20.1) "ENSMUSG00000039367(Sec24c),ENSMUSG00000039234(Sec24d)" "ENSG00000176986(SEC24C),ENSG00000150961(SEC24D)" FBgn0061500 l(2)44Fp lethal (2) 44Fp http://flybase.net/reports/FBgn0061500.html gene l(2)44Fk 16-Dec-15 2015_12 "lethal,recessive" FBgn0267887 CR46175 http://flybase.net/reports/FBgn0267887.html pseudogene_attribute CG12717-related CR46175 16-Dec-15 2015_12 FBgn0262387 mir-190 mir-190 stem loop http://flybase.net/reports/FBgn0262387.html "FBgn0259155, FBgn0262208" miRNA_gene 0046716=muscle cell cellular homeostasis "dme-mir-190, CR42915, miR-190" CR42915 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "eye,wing,wing margin,wing vein,1st posterior cell" FBgn0267760 CR46091 http://flybase.net/reports/FBgn0267760.html non_protein_coding_gene CR46091 16-Dec-15 2015_12 FBgn0031464 Duox Dual oxidase http://flybase.net/reports/FBgn0031464.html protein_coding_gene "0020037=heme binding, 0016175=superoxide-generating NADPH oxidase activity, 0004601=peroxidase activity, 0005509=calcium ion binding" "0048085=adult chitin-containing cuticle pigmentation, 0072593=reactive oxygen species metabolic process, 0043066=negative regulation of apoptotic process, 0019221=cytokine-mediated signaling pathway, 0055114=oxidation-reduction process, 0035220=wing disc development, 0008365=adult chitin-based cuticle development, 0051591=response to cAMP, 0006979=response to oxidative stress, 0002385=mucosal immune response, 0042742=defense response to bacterium, 0042335=cuticle development" 0012505=endomembrane system "dual oxidase, DUOX, duox, NADPH dual oxidase, dduox, CG3131, dDuox" "IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR013121=Ferric reductase, NAD binding domain, IPR010255=Haem peroxidase, IPR002048=EF-hand domain, IPR019791=Haem peroxidase, animal, IPR013130=Ferric reductase transmembrane component-like domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR017938=Riboflavin synthase-like beta-barrel, IPR013112=FAD-binding 8" CG3131 16-Dec-15 2015_12 ENSDARG00000062632(duox1) "WBGene00000253(bli-3),WBGene00018771(duox-2)" "ENSXETG00000007754(),ENSXETG00000023898()" "ENSMUSG00000068452(Duox2),ENSMUSG00000033268(Duox1)" "ENSG00000137857(DUOX1),ENSG00000140279(DUOX2)" "immune response defective,increased cell death,lethal,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "wing,wing vein,ommatidium" FBgn0082622 S(CycEJP)42S33 S(CycEJP)42S33 http://flybase.net/reports/FBgn0082622.html gene 42S33 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001380 l(1)2Bl lethal (1) 2Bl http://flybase.net/reports/FBgn0001380.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040812 CG8750 http://flybase.net/reports/FBgn0040812.html protein_coding_gene CG8750 16-Dec-15 2015_12 viable FBgn0005522 l(2)52Db lethal (2) 52Db http://flybase.net/reports/FBgn0005522.html gene unnamed 16-Dec-15 2015_12 FBgn0031453 Bacc Bacchus http://flybase.net/reports/FBgn0031453.html FBgn0025946 protein_coding_gene "0048149=behavioral response to ethanol, 0002121=inter-male aggressive behavior" "0005634=nucleus, 0005654=nucleoplasm" "anon-EST:Liang-2.54, CG9894, Baccus, clone 2.54" CG9894 16-Dec-15 2015_12 "chemical resistant,dominant,viable,behavior defective,recessive,partially lethal - majority die,fertile" FBgn0001349 l(1)1Ed lethal (1) 1Ed http://flybase.net/reports/FBgn0001349.html gene 16-Dec-15 2015_12 lethal FBgn0042213 CG18731 http://flybase.net/reports/FBgn0042213.html protein_coding_gene IPR028227=Uncharacterised protein family UPF0449 CG18731 16-Dec-15 2015_12 viable DRSC15377 K 0.122779763 1.181857024 -0.310698265 -0.210586874 0.689266881 1.872992678 FBgn0001467 l(1)7Fd lethal (1) 7Fd http://flybase.net/reports/FBgn0001467.html gene l(1)VA67 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0266868 CR45329 http://flybase.net/reports/FBgn0266868.html non_protein_coding_gene CR45329 16-Dec-15 2015_12 FBgn0011976 tRNA:S4:12Eb transfer RNA:ser4:12Eb http://flybase.net/reports/FBgn0011976.html "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052623, FBgn0060062" tRNA_gene "0033408=UCG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:ser4:12Eb, Ser-tRNA-4, transfer RNA:ser, tRNA:S:CGA:AE002593-b, tRNA:S4, Ser tRNA[Ser], unnamed, CR32623, tRNA:S, chrX.trna7-SerCGA, tRNA:ser, transfer RNA:ser4, 444-2, tRNA:ser4, tRNA[[Ser]], AE002593.trna3-SerCGA, tRNA[Ser], tRNA-Ser" CR32623 16-Dec-15 2015_12 FBgn0028540 CG9008 http://flybase.net/reports/FBgn0028540.html "FBgn0027905, FBtr0080576, FBpp0080153, FBtr0080577, FBpp0080154, FBtr0080578, FBpp0080155" protein_coding_gene "0030246=carbohydrate binding, 0016853=isomerase activity" "0005975=carbohydrate metabolic process, 0007030=Golgi organization, 0034389=lipid particle organization" BG:DS00797.2 "IPR014718=Glycoside hydrolase-type carbohydrate-binding, subgroup, IPR011013=Galactose mutarotase-like domain, IPR025532=Glucose-6-phosphate 1-epimerase, IPR008183=Aldose 1-/Glucose-6-phosphate 1-epimerase" CG9008 16-Dec-15 2015_12 YMR099C() "lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "microchaeta & mesothoracic tergumë±Tub84B.PL,trichogen cell,mesothoracic tergum" FBgn0264738 CG43996 http://flybase.net/reports/FBgn0264738.html FBgn0030811 protein_coding_gene CG12433 CG43996 16-Dec-15 2015_12 viable FBgn0036923 CG17732 http://flybase.net/reports/FBgn0036923.html protein_coding_gene CG17732 16-Dec-15 2015_12 viable FBgn0265210 ninaE::Btau\RHO http://flybase.net/reports/FBgn0265210.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0266798 CR45260 http://flybase.net/reports/FBgn0266798.html non_protein_coding_gene CR45260 16-Dec-15 2015_12 FBgn0062611 Mod(var)1310 Mod(var)1310 http://flybase.net/reports/FBgn0062611.html gene 0006342=chromatin silencing 1310 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0016841 l(1)N1 lethal (1) N1 http://flybase.net/reports/FBgn0016841.html gene N1 16-Dec-15 2015_12 "lethal,recessive" FBgn0003512 Sry-ë« Serendipity ë« http://flybase.net/reports/FBgn0003512.html FBgn0014946 protein_coding_gene "0003677=DNA binding, 0046872=metal ion binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0048477=oogenesis, 0032504=multicellular organism reproduction, 0008595=anterior/posterior axis specification, embryo, 0006355=regulation of transcription, DNA-templated" "0005634=nucleus, 0005705=polytene chromosome interband" "anon-EH8, Sry-delta, EH8, CG17958, serendipity-delta, serendipity delta, sry delta, sry-delta, sry, Sry delta, Srydelta, Serendipity delta, srydelta" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG17958 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage >S10B , oogenesis stage | stage , nurse cell

, organism

" " embryonic stage | stage 12-17 , embryonic stage | stage >5 , embryonic stage | stage <5 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S>12 " " embryonic/larval pharynx

,

, nurse cell

, ventral nerve cord

, supraesophageal ganglion

, oocyte , follicle cell

" "wild-type,lethal,recessive,partially" "testis,embryonic/first instar larval cuticle,embryonic/first instar larval cuticle & thoracic segment,telson,posterior,gonad,male,spermatozoon,cephalopharyngeal skeleton" FBgn0038113 CG11668 http://flybase.net/reports/FBgn0038113.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP115 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG11668 16-Dec-15 2015_12 viable FBgn0262734 Rbp2 RNA-binding protein 2 http://flybase.net/reports/FBgn0262734.html "FBgn0010256, FBgn0025264, FBgn0030754, FBgn0086541" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding, 0003743=translation initiation factor activity" 0006413=translational initiation "0005875=microtubule associated complex, 0005829=cytosol" "anon-fast-evolving-1B9, eIF4H, cg4429, RRM2, anon-EST:fe1B9, rrm2, MRE9, CG4429, mRNA-like ncRNA in embryogenesis 9" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG4429 16-Dec-15 2015_12 ENSXETG00000018230(wbscr1) ENSMUSG00000040731(Eif4h) ENSG00000106682(EIF4H) FBgn0259855 Su(Ste):CR42424 Su(Ste):CR42424 http://flybase.net/reports/FBgn0259855.html non_protein_coding_gene CR42424 CR42424 16-Dec-15 2015_12 FBgn0267889 CR46177 http://flybase.net/reports/FBgn0267889.html pseudogene_attribute Mst35Ba-related CR46177 16-Dec-15 2015_12 FBgn0017386 l(1)15De lethal (1) 15De http://flybase.net/reports/FBgn0017386.html gene 16-Dec-15 2015_12 lethal FBgn0003633 Su(var)327 Suppressor of variegation 327 http://flybase.net/reports/FBgn0003633.html gene 327 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0030915 CG6179 http://flybase.net/reports/FBgn0030915.html protein_coding_gene 0044822=poly(A) RNA binding "0051001=negative regulation of nitric-oxide synthase activity, 0000398=mRNA splicing, via spliceosome, 0043086=negative regulation of catalytic activity" "0005634=nucleus, 0005737=cytoplasm, 0071013=catalytic step 2 spliceosome" NOSIPL "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR016818=Nitric oxide synthase-interacting" CG6179 16-Dec-15 2015_12 ENSDARG00000037958(nosip) WBGene00019898(R05G6.4) ENSXETG00000017642(Q6P829_XENTR) ENSMUSG00000003421(Nosip) ENSG00000142546(NOSIP) "viable,fertile" FBgn0002271 l(3)69Bc lethal (3) 69Bc http://flybase.net/reports/FBgn0002271.html gene "l(3)rsg33, rsg33, rose-gespleten region interval 33" 16-Dec-15 2015_12 lethal FBgn0052076 Alg10 Alpha 3 glucosyltransferase http://flybase.net/reports/FBgn0052076.html FBgn0036140 protein_coding_gene "0004583=dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity, 0004576=oligosaccharyl transferase activity, 0046527=glucosyltransferase activity" "0006487=protein N-linked glycosylation, 0006488=dolichol-linked oligosaccharide biosynthetic process" "0005789=endoplasmic reticulum membrane, 0005783=endoplasmic reticulum" "alg10, CG7624, CG32076, dAlg10" IPR016900=Alpha-2-glucosyltransferase Alg10 CG32076 16-Dec-15 2015_12 ENSDARG00000053917 YGR227W(DIE2) WBGene00007043(tag-179) ENSXETG00000025516() ENSMUSG00000075470(Alg10b) "ENSG00000175548(ALG10B),ENSG00000139133(ALG10)" FBgn0039237 CG13640 http://flybase.net/reports/FBgn0039237.html FBgn0062979 protein_coding_gene BcDNA:RE70528 CG13640 16-Dec-15 2015_12 "viable,fertile" FBgn0030673 CG15601 http://flybase.net/reports/FBgn0030673.html protein_coding_gene IPR006578=MADF domain CG15601 16-Dec-15 2015_12 viable DRSC19670 K -0.05866301 0.335403336 -0.049939983 0.56349732 -0.115180018 1.602430298 FBgn0015682 elav::Dvir\elav elav::Dvir\elav http://flybase.net/reports/FBgn0015682.html engineered_fusion_gene "elav, unnamed" 16-Dec-15 2015_12 "lethal,recessive,sterile" FBgn0026666 l(1)G0136 lethal (1) G0136 http://flybase.net/reports/FBgn0026666.html "FBgn0030677, FBgn0063708" protein_coding_gene "0005198=structural molecule activity, 0051536=iron-sulfur cluster binding" 0016226=iron-sulfur cluster assembly "CG8198, IscA1 homologue, BcDNA:AT26381" "IPR016092=FeS cluster insertion protein, IPR000361=FeS cluster biogenesis, IPR017870=FeS cluster insertion, C-terminal, conserved site" CG8198 16-Dec-15 2015_12 ENSDARG00000051956(isca1) WBGene00012666(Y39B6A.3) "ENSMUSG00000044792(Isca1),ENSMUSG00000078139(AK157302)" "ENSG00000135070(ISCA1),ENSG00000217416" "lethal,recessive,locomotor rhythm defective" DRSC20092 IK -0.358861444 -1.540499237 -0.490274825 0.13959556 2.862034549 -0.133821632 FBgn0050440 CG30440 http://flybase.net/reports/FBgn0050440.html "FBgn0033024, FBgn0033025, FBgn0033026" protein_coding_gene "0005089=Rho guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity" 0035025=positive regulation of Rho protein signal transduction "CG10412, CG10416, CG12183" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001331=Guanine-nucleotide dissociation stimulator, CDC24, conserved site, IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain" CG30440 16-Dec-15 2015_12 "ENSXETG00000007761(),ENSXETG00000018712(ARHGEF5)" viable FBgn0024675 l(2)k00313 lethal (2) k00313 http://flybase.net/reports/FBgn0024675.html gene 13-Mar 16-Dec-15 2015_12 "lethal,recessive" FBgn0039448 TwdlQ TweedleQ http://flybase.net/reports/FBgn0039448.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix CG14250 IPR004145=Domain of unknown function DUF243 CG14250 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028046 l(3)S096901b lethal (3) S096901b http://flybase.net/reports/FBgn0028046.html gene "0969/01, l(3)S096901" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051496 CG31496 http://flybase.net/reports/FBgn0051496.html FBgn0037499 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG14604 CG31496 16-Dec-15 2015_12 viable FBgn0051051 CG31051 http://flybase.net/reports/FBgn0051051.html "FBgn0039587, FBgn0063638" protein_coding_gene "CG1540, CT3186" CG31051 16-Dec-15 2015_12 viable DRSC15034 E -0.112870161 0.915641129 0.359011628 1.623710019 0.425581888 0.435726266 FBgn0086057 snoRNA:Me28S-G2017 http://flybase.net/reports/FBgn0086057.html snoRNA_gene "Me28S-C2017, Me28S-Gm2017, CR34686" CR34686 16-Dec-15 2015_12 FBgn0259474 EP-738 http://flybase.net/reports/FBgn0259474.html gene 16-Dec-15 2015_12 visible wing vein L3 FBgn0263950 BG00817 http://flybase.net/reports/FBgn0263950.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0026778 Rad1 Radiation insensitive 1 http://flybase.net/reports/FBgn0026778.html protein_coding_gene "0004527=exonuclease activity, 0003684=damaged DNA binding" "0006281=DNA repair, 0000077=DNA damage checkpoint" 0030896=checkpoint clamp complex "Rad1[Dm], DmRad1, Rad1, CG3240, rad1, Dromel_CG3240_FBtr0077747_rad1_mORF" "IPR003011=Cell cycle checkpoint protein, Rad1, IPR003021=Rad1/Rec1/Rad17" CG3240 16-Dec-15 2015_12 ENSDARG00000040559(rad1) WBGene00003417(mrt-2) ENSXETG00000000705() ENSMUSG00000022248(Rad1) ENSG00000113456(RAD1) "viable,fertile" FBgn0001720 l(1)ESHS41 lethal (1) ESHS41 http://flybase.net/reports/FBgn0001720.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086301 mace mace http://flybase.net/reports/FBgn0086301.html gene 0046847=filopodium assembly 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" "dendrite | larval stage,dorsal multidendritic neuron ddaA & filopodium" FBgn0085195 CG34166 http://flybase.net/reports/FBgn0085195.html protein_coding_gene CG15281 CG34166 16-Dec-15 2015_12 FBgn0028195 l(3)S022348 lethal (3) S022348 http://flybase.net/reports/FBgn0028195.html gene 0223/48 16-Dec-15 2015_12 "lethal,recessive" FBgn0035375 pgant6 polypeptide GalNAc transferase 6 http://flybase.net/reports/FBgn0035375.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process "0005795=Golgi stack, 0005783=endoplasmic reticulum" "Polypeptide GalNAc transferase 6, CG2103, Pgant6" "IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain, IPR029044=Nucleotide-diphospho-sugar transferases" CG2103 16-Dec-15 2015_12 ENSDARG00000042778(galnt10) WBGene00001635(gly-10) "ENSXETG00000008481(GALNT10),ENSXETG00000016922(GALNTL6)" ENSMUSG00000020520(Galnt10) "ENSG00000164574(GALNT10),ENSG00000174473(GALNTL6)" "viable,fertile,partially lethal - majority die" DRSC26927 K -0.127862827 -0.704383345 1.214036843 0.174381164 -0.643245135 1.533963867 FBgn0067758 l(1)G0029 lethal (1) G0029 http://flybase.net/reports/FBgn0067758.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0027655 htt huntingtin http://flybase.net/reports/FBgn0027655.html protein_coding_gene "0008088=axon cargo transport, 0048812=neuron projection morphogenesis, 0048489=synaptic vesicle transport, 0000132=establishment of mitotic spindle orientation" 0005737=cytoplasm "CG9995, HTT, Hsap\HD, HD, Huntingtin, dHtt, DmHtt, dhtt, Htt" "IPR028426=Huntingtin family, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR024613=Huntingtin, middle-repeat" CG9995 16-Dec-15 2015_12 ENSDARG00000052866(htt) ENSMUSG00000029104(Htt) ENSG00000197386(HTT) "viable,fertile,short lived,visible,progressive,neuroanatomy defective,sleep defective" "axon | larval stageAppl.G1a,embryonic/larval brain,eye,ommatidium,progressive" FBgn0019872 l(3)96Ab lethal (3) 96Ab http://flybase.net/reports/FBgn0019872.html gene "anon-96Ab, 299.1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0264268 CR43768 http://flybase.net/reports/FBgn0264268.html non_protein_coding_gene CR43768 16-Dec-15 2015_12 FBgn0265529 CR44379 http://flybase.net/reports/FBgn0265529.html non_protein_coding_gene lincRNA.327 CR44379 16-Dec-15 2015_12 FBgn0037632 Tcp-1ëá Tcp-1ëá http://flybase.net/reports/FBgn0037632.html protein_coding_gene "0051082=unfolded protein binding, 0042623=ATPase activity, coupled, 0005524=ATP binding" "0031122=cytoplasmic microtubule organization, 0022008=neurogenesis, 0006457=protein folding, 0090307=mitotic spindle assembly, 0007052=mitotic spindle organization" "0005875=microtubule associated complex, 0005832=chaperonin-containing T-complex, 0005829=cytosol" "TCP1-zeta homologue, tcp1eta, tcp-1eta, Tcp-1-eta1, Cct7, Q9VHL2_DROME, Tcp-1eta, CG8351" "IPR027413=GroEL-like equatorial domain, IPR027409=GroEL-like apical domain, IPR002194=Chaperonin TCP-1, conserved site, IPR012720=T-complex protein 1, eta subunit, IPR027410=TCP-1-like chaperonin intermediate domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1)" CG8351 16-Dec-15 2015_12 ENSDARG00000007385(cct7) YJL111W(CCT7) WBGene00020391(cct-7) ENSXETG00000011778(cct7) ENSMUSG00000030007(Cct7) ENSG00000135624(CCT7) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0053505 U3-55K U3 small nuclear riboprotein factor 55K http://flybase.net/reports/FBgn0053505.html "FBgn0033974, FBtr0087459, FBpp0086589" protein_coding_gene "0034511=U3 snoRNA binding, 0003729=mRNA binding" "0022008=neurogenesis, 0006364=rRNA processing" 0030532=small nuclear ribonucleoprotein complex "CG33505, CG10220" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG33505 16-Dec-15 2015_12 ENSDARG00000041991(rnu3ip2) YPR137W(RRP9) WBGene00020171(T02H6.1) ENSMUSG00000041506(Rrp9) ENSG00000114767(RRP9) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000838 fs(1)M24 female sterile (1) M24 http://flybase.net/reports/FBgn0000838.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0031434 insv insensitive http://flybase.net/reports/FBgn0031434.html FBgn0047090 protein_coding_gene 0003714=transcription corepressor activity 0045746=negative regulation of Notch signaling pathway 0005634=nucleus "Insv, insensitive, insv, BcDNA:RE55538, Insensitive, CG3227" IPR018379=BEN domain CG3227 16-Dec-15 2015_12 "viable,visible" "microchaeta,adult abdominal sensillum,tormogen cell,ectopic,trichogen cell,macrochaeta,supernumerary,wing margin" FBgn0010846 l(3)04696 lethal (3) 04696 http://flybase.net/reports/FBgn0010846.html gene 4712 16-Dec-15 2015_12 "lethal,recessive" FBgn0000310 cho chocolate http://flybase.net/reports/FBgn0000310.html gene 0048072=compound eye pigmentation 16-Dec-15 2015_12 "eye color defective,viable,fertile" "pigment cell,Malpighian tubule" FBgn0259972 Sfp77F Seminal fluid protein 77F http://flybase.net/reports/FBgn0259972.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 77F, CG42482" CG42482 16-Dec-15 2015_12 FBgn0020520 plt platonic http://flybase.net/reports/FBgn0020520.html gene 0007620=copulation 16-Dec-15 2015_12 FBgn0265535 CG44385 http://flybase.net/reports/FBgn0265535.html protein_coding_gene CG44385 16-Dec-15 2015_12 FBgn0022255 l(2)k01103 lethal (2) k01103 http://flybase.net/reports/FBgn0022255.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051409 CG31409 http://flybase.net/reports/FBgn0051409.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035737 Cpr65Ec Cuticular protein 65Ec http://flybase.net/reports/FBgn0035737.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr65Ec, CG8634" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8634 16-Dec-15 2015_12 FBgn0014119 anon-96Fd anon-96Fd http://flybase.net/reports/FBgn0014119.html gene B transcript 16-Dec-15 2015_12 " larval stage , adult stage " " eye-antennal disc

, adult head

" FBgn0264436 CR43854 http://flybase.net/reports/FBgn0264436.html non_protein_coding_gene CR43854 16-Dec-15 2015_12 FBgn0002160 l(2)Sp1 lethal (2) Sp1 http://flybase.net/reports/FBgn0002160.html gene 16-Dec-15 2015_12 lethal FBgn0265075 CR44186 http://flybase.net/reports/FBgn0265075.html non_protein_coding_gene CR44186 16-Dec-15 2015_12 FBgn0010458 l(2)00231 lethal (2) 00231 http://flybase.net/reports/FBgn0010458.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266408 CR45048 http://flybase.net/reports/FBgn0266408.html non_protein_coding_gene CR45048 16-Dec-15 2015_12 FBgn0058219 CG40219 http://flybase.net/reports/FBgn0058219.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060710 l(3)S070209b lethal (3) S070209b http://flybase.net/reports/FBgn0060710.html gene 0702/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0028101 l(3)S072613a lethal (3) S072613a http://flybase.net/reports/FBgn0028101.html gene "l(3)S072613, 0726/13" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0003330 Sce Sex combs extra http://flybase.net/reports/FBgn0003330.html FBgn0020911 protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0035518=histone H2A monoubiquitination, 0022008=neurogenesis, 0030708=germarium-derived female germ-line cyst encapsulation, 0007275=multicellular organismal development, 0045498=sex comb development, 0006342=chromatin silencing, 0007062=sister chromatid cohesion, 0030713=ovarian follicle cell stalk formation" "0008278=cohesin complex, 0035102=PRC1 complex, 0005634=nucleus, 0031519=PcG protein complex, 0005730=nucleolus" "Ding, dRing, DRING, Sce/dRing, Rnf2, Dring, Sex comb extra, dRING, Ring, CG5595, RING1, SCE, Ring/Sce, RING, dring, sce, dRING1, dRing1" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR018957=Zinc finger, C3HC4 RING-type, IPR001841=Zinc finger, RING-type" CG5595 16-Dec-15 2015_12 ENSDARG00000010381(rnf2) "ENSXETG00000026022(rnf2),ENSXETG00000020370(RING1)" "ENSMUSG00000026484(Rnf2),ENSMUSG00000024325(Ring1)" "ENSG00000206287,ENSG00000206215,ENSG00000204227(RING1),ENSG00000121481(RNF2)" "lethal - all die before end of pupal stage,some die during pupal stage,suppressor of variegation,dominant,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,somatic clone,mitotic cell cycle defective,tumorigenic,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die" "adult thorax,Fell hairs,ectopic,abdominal 4 ventral denticle belt,denticle belt,embryonic abdominal segment,rescuable maternal effect,embryonic abdominal segment 8,embryonic head,stage 14 embryo,embryonic thoracic segment,larval abdominal segment 7,larval abdominal segment 1,germline clone,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,Keilin's organ,Kolbchen,egg chamber,somatic clone,germarium region 3,interfollicle cell,cell non-autonomous,neuroblast,embryonic/larval tracheal system,eye disc,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,wing,mesothoracic tergum" FBgn0024968 FebpN ftz enhancer binding protein N http://flybase.net/reports/FBgn0024968.html gene 0003677=DNA binding 0005634=nucleus protein N 16-Dec-15 2015_12 FBgn0020871 anon-Q177 anon-Q177 http://flybase.net/reports/FBgn0020871.html gene 2-Q177 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0032031 CG13390 http://flybase.net/reports/FBgn0032031.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0000287=magnesium ion binding" "IPR014100=GTP-binding protein Obg/CgtA, IPR005225=Small GTP-binding protein domain, IPR031167=OBG-type guanine nucleotide-binding (G) domain, IPR006169=GTP1/OBG domain, IPR006073=GTP binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG13390 16-Dec-15 2015_12 ENSDARG00000063574(si:dkeyp-44b8.7) YHR168W(MTG2) WBGene00010805(M01E5.2) ENSXETG00000002001(gtpbp5) ENSMUSG00000039069(Gtpbp5) ENSG00000101181(GTPBP5) viable FBgn0086075 snoRNA:Me28S-G3253 http://flybase.net/reports/FBgn0086075.html snoRNA_gene "CR34704, Me28S-G3253, snoRNA:28S-G3253, 28S-Gm3253" CR34704 16-Dec-15 2015_12 FBgn0262396 mir-314 mir-314 stem loop http://flybase.net/reports/FBgn0262396.html "FBgn0067690, FBgn0262226" miRNA_gene "mir-314, miR-314, dme-mir-314, dme-miR-314-5p, CR33618, CR42933" CR42933 16-Dec-15 2015_12 viable FBgn0039003 wfs1 wolfram syndrome 1 http://flybase.net/reports/FBgn0039003.html protein_coding_gene 0004357=glutamate-cysteine ligase activity 0017109=glutamate-cysteine ligase complex CG4917 "IPR011990=Tetratricopeptide-like helical domain, IPR026209=Wolframin family" CG4917 16-Dec-15 2015_12 ENSDARG00000062341(wfs1) ENSXETG00000011603(WFS1) ENSMUSG00000039474(Wfs1) ENSG00000109501(WFS1) "viable,fertile" DRSC15676 K -0.271374309 0.719126685 -0.050197093 0.042517314 2.625593023 0.835816879 FBgn0036608 CG13040 http://flybase.net/reports/FBgn0036608.html protein_coding_gene IPR007614=Retinin-like protein CG13040 16-Dec-15 2015_12 viable FBgn0062528 l(3)88EFd lethal (3) 88EFd http://flybase.net/reports/FBgn0062528.html gene 16-Dec-15 2015_12 lethal FBgn0000587 E(S) Enhancer of Star http://flybase.net/reports/FBgn0000587.html gene 16-Dec-15 2015_12 "visible,recessive" eye FBgn0259286 C575 http://flybase.net/reports/FBgn0259286.html gene 16-Dec-15 2015_12 visible wing FBgn0053222 CR33222 http://flybase.net/reports/FBgn0053222.html FBgn0029973 pseudogene_attribute "CG33222, CR11386" CR33222 16-Dec-15 2015_12 FBgn0039925 Kif3C Kinesin family member 3C ortholog http://flybase.net/reports/FBgn0039925.html FBgn0039926 protein_coding_gene "0003777=microtubule motor activity, 0008017=microtubule binding, 0008569=ATP-dependent microtubule motor activity, minus-end-directed, 0005524=ATP binding" "0048812=neuron projection morphogenesis, 0007018=microtubule-based movement" 0005871=kinesin complex "Kif3c, CG17461, CG17459, KIF3C, DmKif3C, CP38609, Kif3C, KIF17, Kinesin Superfamily Protein 3C, DmKIF3C, KIF 3C, KIF3Cdm, KIF 24" "IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027640=Kinesin-like protein" CG17461 16-Dec-15 2015_12 YEL061C(CIN8) WBGene00003884(osm-3) ENSMUSG00000028758(Kif17) ENSG00000117245(KIF17) viable FBgn0001230 Hsp68 Heat shock protein 68 http://flybase.net/reports/FBgn0001230.html protein_coding_gene 0051082=unfolded protein binding "0042594=response to starvation, 0008340=determination of adult lifespan, 0031427=response to methotrexate, 0006457=protein folding, 0009408=response to heat, 0022008=neurogenesis" "0005875=microtubule associated complex, 0005739=mitochondrion, 0005811=lipid particle" "DmHsp68, CG5436, Hsp 68, heat shock protein 68, hsp68, HSP68, 68, Hsp-68, HSP68_DROME" "IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR018181=Heat shock protein 70, conserved site, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR013126=Heat shock protein 70 family" CG5436 16-Dec-15 2015_12 "chemical resistant,long lived,starvation stress response defective,body color defective,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0067748 l(1)G0210 lethal (1) G0210 http://flybase.net/reports/FBgn0067748.html gene 16-Dec-15 2015_12 male sterile FBgn0002953 nofG no object fixation G http://flybase.net/reports/FBgn0002953.html gene 16-Dec-15 2015_12 behavior defective eye FBgn0038429 CG14882 http://flybase.net/reports/FBgn0038429.html FBgn0046757 protein_coding_gene "0016491=oxidoreductase activity, 0016709=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, 0030586=[methionine synthase] reductase activity, 0003958=NADPH-hemoprotein reductase activity" 0055114=oxidation-reduction process 0005829=cytosol BcDNA:SD10961 "IPR017938=Riboflavin synthase-like beta-barrel, IPR023173=NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3, IPR003097=FAD-binding, type 1, IPR001709=Flavoprotein pyridine nucleotide cytochrome reductase, IPR001433=Oxidoreductase FAD/NAD(P)-binding, IPR017927=Ferredoxin reductase-type FAD-binding domain" CG14882 16-Dec-15 2015_12 ENSXETG00000002236(mtrr) viable FBgn0038029 GstD11 Glutathione S transferase D11 http://flybase.net/reports/FBgn0038029.html FBgn0063668 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "cg17639, DmGSTD11, CG17639, gstd11, GSTD11, BcDNA:RE72392" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like" CG17639 16-Dec-15 2015_12 YNL229C(URE2) "viable,fertile" FBgn0260255 GSd226 http://flybase.net/reports/FBgn0260255.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0039103 CG13819 http://flybase.net/reports/FBgn0039103.html protein_coding_gene 16-Dec-15 2015_12 DRSC14669 I -0.169621679 4.818628291 0.59764478 0.699219966 0.125739588 -0.867770565 FBgn0267351 Topors Topoisomerase I-interacting protein http://flybase.net/reports/FBgn0267351.html "FBgn0034410, FBgn0069095" protein_coding_gene "0061630=ubiquitin protein ligase activity, 0008270=zinc ion binding, 0044547=DNA topoisomerase binding" "0071763=nuclear membrane organization, 0007060=male meiosis chromosome segregation, 0007140=male meiosis, 0007095=mitotic G2 DNA damage checkpoint, 0000209=protein polyubiquitination, 0010032=meiotic chromosome condensation, 0006511=ubiquitin-dependent protein catabolic process, 0051299=centrosome separation" "0005700=polytene chromosome, 0005652=nuclear lamina, 0005634=nucleus" "TOPORS, CG15104, dtopors, nuclear blebber, nbl, dTopors" "IPR018957=Zinc finger, C3HC4 RING-type, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site" CG15104 16-Dec-15 2015_12 ENSDARG00000037260(si:ch211-145b13.4) ENSXETG00000014724(TEgg124o06.1) ENSMUSG00000036822(Topors) ENSG00000197579(TOPORS) DRSC06531 I -0.762372109 1.654920577 0.585662723 -1.185527546 0.456563597 0.994001174 FBgn0015760 Map85 Microtubule-associated protein 85 http://flybase.net/reports/FBgn0015760.html gene 0005875=microtubule associated complex DMAP-85 16-Dec-15 2015_12 embryonic stage&& larval stage&& adult stage " embryonic stage | early , embryonic stage | 10-15hr , larval stage , embryonic stage | late , embryonic stage | 5hr , embryonic stage | mid , embryonic stage | 1-4hr , embryonic stage | 6-9hr " " longitudinal connective

, embryonic central nervous system

, connective

, amnioserosa

" FBgn0005182 l(2)S4 lethal of Seto 4 http://flybase.net/reports/FBgn0005182.html gene 16-Dec-15 2015_12 lethal "puparium,epidermis" FBgn0085825 CR41619 http://flybase.net/reports/FBgn0085825.html FBan0041619 rRNA_gene CR41619 16-Dec-15 2015_12 FBgn0024725 Su(var)28D Su(var)28D http://flybase.net/reports/FBgn0024725.html gene unnamed 16-Dec-15 2015_12 FBgn0005469 l(1)ts340 lethal (1) ts340 http://flybase.net/reports/FBgn0005469.html FBgn0001830 gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0034885 CG4019 http://flybase.net/reports/FBgn0034885.html protein_coding_gene "0015267=channel activity, 0015250=water channel activity" "0003014=renal system process, 0055085=transmembrane transport" 0016021=integral component of membrane Aqp4019 "IPR000425=Major intrinsic protein, IPR022357=Major intrinsic protein, conserved site, IPR023271=Aquaporin-like" CG4019 16-Dec-15 2015_12 YPR192W(AQY1) "viable,lethal" FBgn0051198 CG31198 http://flybase.net/reports/FBgn0051198.html "FBgn0038899, FBgn0044630, FBgn0044763" protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "anon-WO0140519.12, anon-WO0140519.24, CG5845" "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain" CG31198 16-Dec-15 2015_12 viable FBgn0036622 CG4753 http://flybase.net/reports/FBgn0036622.html protein_coding_gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity 0008152=metabolic process AGPAT4 IPR002123=Phospholipid/glycerol acyltransferase CG4753 16-Dec-15 2015_12 "ENSDARG00000069044(agpat4),ENSDARG00000036549(LOC100334774)" "YDR018C(),YBR042C(CST26)" "WBGene00020264(acl-8),WBGene00044631(bus-18),WBGene00022646(acl-9)" "ENSXETG00000017998(agpat3),ENSXETG00000013131(agpat4)" "ENSMUSG00000001211(Agpat3),ENSMUSG00000023827(Agpat4)" "ENSG00000160216(AGPAT3),ENSG00000026652(AGPAT4)" "viable,fertile" FBgn0028981 tRNA:S4:56D transfer RNA:ser4:56D http://flybase.net/reports/FBgn0028981.html "FBgn0011968, FBgn0011973, FBgn0011978, FBgn0050224, FBgn0060060" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033408=UCG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:ser, transfer RNA:ser4, EST E, tRNA(4Ser), AE002787.trna50-SerCGA, tRNA[Ser], tRNA[Ser][[4]], transfer RNA:ser, CR30224, chr2R.trna33-SerCGA, tRNA:ser4, tRNA[[Ser]], Ser tRNA[Ser], tRNA:S, tRNA:ser4:64D, 444-3, tRNA:S4, tRNA:S4:64D, tRNA:S:CGA:AE002787" CR30224 16-Dec-15 2015_12 FBgn0069065 5SrRNA-ë¬ 5S ribosomal RNA pseudogene http://flybase.net/reports/FBgn0069065.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0267280 CR45716 http://flybase.net/reports/FBgn0267280.html pseudogene_attribute CR45716 16-Dec-15 2015_12 FBgn0011769 Fdx1 Ferredoxin 1 http://flybase.net/reports/FBgn0011769.html FBgn0062914 protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding, 0009055=electron carrier activity" "0035073=pupariation, 0045998=positive regulation of ecdysteroid biosynthetic process" 0005739=mitochondrion "BcDNA:RH67819, ferredoxin, Fdxh, Ferredoxin, CG4205" "IPR001055=Adrenodoxin, IPR012675=Beta-grasp domain, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR018298=Adrenodoxin, iron-sulphur binding site" CG4205 16-Dec-15 2015_12 ENSDARG00000052190(zgc:153554) YPL252C(YAH1) WBGene00013532(Y73F8A.27) ENSXETG00000021499(FDX1L) ENSMUSG00000079677(Fdx1l) ENSG00000167807(FDX1L) viable FBgn0052647 CG32647 http://flybase.net/reports/FBgn0052647.html "FBgn0030422, FBgn0030423, FBgn0042226, FBgn0062941" protein_coding_gene "CT35953, CG15723, CG3794, CG18453, BcDNA:RH40632" IPR001007=VWFC domain CG32647 16-Dec-15 2015_12 "viable,fertile" FBgn0060674 l(3)S077515 lethal (3) S077515 http://flybase.net/reports/FBgn0060674.html gene 0775/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0085413 CG34384 http://flybase.net/reports/FBgn0085413.html "FBgn0037524, FBgn0037523, FBgn0040523, FBgn0051187" protein_coding_gene 0004143=diacylglycerol kinase activity "0051259=protein oligomerization, 0035556=intracellular signal transduction, 0016310=phosphorylation, 0007205=protein kinase C-activating G-protein coupled receptor signaling pathway" "0005737=cytoplasm, 0005768=endosome" "CG31187, dgkd, DGKd, CG2667, CG14462, CG9851" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000756=Diacylglycerol kinase, accessory domain, IPR013761=Sterile alpha motif/pointed domain, IPR001206=Diacylglycerol kinase, catalytic domain, IPR001660=Sterile alpha motif domain, IPR001849=Pleckstrin homology domain" CG34384 16-Dec-15 2015_12 ENSDARG00000018716(si:ch211-93a19.1) WBGene00006483(dgk-4) "ENSXETG00000014560(DGKH),ENSXETG00000022599()" ENSMUSG00000034731(Dgkh) "ENSG00000077044(DGKD),ENSG00000102780(DGKH)" FBgn0032442 CG15485 http://flybase.net/reports/FBgn0032442.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain" CG15485 16-Dec-15 2015_12 viable FBgn0037225 TwdlG TweedleG http://flybase.net/reports/FBgn0037225.html FBan0014643 protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix "Tweedle G, CG14643" IPR004145=Domain of unknown function DUF243 CG14643 16-Dec-15 2015_12 viable FBgn0020371 Tim17b2 Translocase inner membrane 17 http://flybase.net/reports/FBgn0020371.html "FBgn0032565, FBgn0065011, FBgn0065023" protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0006626=protein targeting to mitochondrion, 0015031=protein transport" 0005744=mitochondrial inner membrane presequence translocase complex "BcDNA:AT13511, dmTim17, CG15257, BG:DS01845.2, BcDNA:AT05822, Tim17" "IPR005678=Mitochondrial inner membrane translocase complex, subunit Tim17, IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24" CG15257 16-Dec-15 2015_12 viable FBgn0261873 sdt stardust http://flybase.net/reports/FBgn0261873.html "FBgn0243505, FBgn0040927, FBgn0052717, FBgn0030024, FBgn0030023, FBgn0030022, FBgn0030021, FBgn0030020, FBgn0025216, FBgn0001465, FBgn0003349, FBgn0052716, FBgn0030019, FBgn0082843" protein_coding_gene "0005515=protein binding, 0004385=guanylate kinase activity" "0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0002009=morphogenesis of an epithelium, 0045186=zonula adherens assembly, 0046331=lateral inhibition, 0045196=establishment or maintenance of neuroblast polarity, 0040003=chitin-based cuticle development, 0001738=morphogenesis of a polarized epithelium, 0045176=apical protein localization, 0007163=establishment or maintenance of cell polarity, 0007043=cell-cell junction assembly, 0042461=photoreceptor cell development, 0016332=establishment or maintenance of polarity of embryonic epithelium" "0016327=apicolateral plasma membrane, 0035003=subapical complex, 0016020=membrane, 0005886=plasma membrane, 0045179=apical cortex, 0005913=cell-cell adherens junction, 0005918=septate junction, 0016324=apical plasma membrane, 0005912=adherens junction" "cGUK1, l(1)7Ef, CG15341, CG12658, anon-fast-evolving-2E6, CG32717, CG12657, cMAGUK1, CG1617, CG15339, PALS1, std, Pals1, anon-EST:fe2E6, BP1063, Std, CG15340, unnamed, Sdt, CG15342, Stardust, pal1" "IPR001478=PDZ domain, IPR020590=Guanylate kinase, conserved site, IPR001452=SH3 domain, IPR004172=L27 domain, IPR031185=MAGUK p55 subfamily member 5, IPR008144=Guanylate kinase-like domain, IPR014775=L27 domain, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011511=Variant SH3 domain, IPR008145=Guanylate kinase/L-type calcium channel beta subunit" CG32717 16-Dec-15 2015_12 ENSXETG00000011220(MPP5) pupal stage photoreceptor cell stalk | apical

FBgn0000420 dbl dichaete beadex lethal http://flybase.net/reports/FBgn0000420.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,cold sensitive" wing FBgn0051529 CG31529 http://flybase.net/reports/FBgn0051529.html FBgn0047233 protein_coding_gene BcDNA:LD01463 16-Dec-15 2015_12 FBgn0030250 CG15206 http://flybase.net/reports/FBgn0030250.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028519 CG4500 http://flybase.net/reports/FBgn0028519.html FBgn0019862 protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity "0001676=long-chain fatty acid metabolic process, 0007498=mesoderm development" "I, anon-EST:CL2a9, 2a9, BG:DS05899.1" IPR000873=AMP-dependent synthetase/ligase CG4500 16-Dec-15 2015_12 "ENSDARG00000062077(LOC100006023),ENSDARG00000004094(acsbg2)" "ENSXETG00000009756(ACSBG1),ENSXETG00000021876(ACSBG2)" "ENSMUSG00000032281(Acsbg1),ENSMUSG00000024207(Acsbg2)" "ENSG00000130377(ACSBG2),ENSG00000103740(ACSBG1)" " embryonic stage | stage 5 , embryonic stage | stage 17 , embryonic stage , embryonic stage | stage >5 " " mesoderm anlage

, embryonic/larval fat body

, ventral furrow

, yolk

, mesoderm

" viable FBgn0061037 l(3)S023844b lethal (3) S023844b http://flybase.net/reports/FBgn0061037.html gene 0238/44 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040007 RpL38 Ribosomal protein L38 http://flybase.net/reports/FBgn0040007.html "FBan0018001, FBgn0002066, FBgn0002601, FBgn0013538, FBgn0020393, FBgn0058278, FBgn0061397" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "Minute(2)41A, CG18001, M(2)S2, CG40278, GroupIV, 41Ag, M(2)S3, lethal(2)41Af, 41Af, Rp L38, l(2)41Af, l(2)41Ai, l(2R)A', Ribosomal protein 38, Nipped, M(2)41A, BcDNA:RE42506, l(2)41Ag, Enhancer on chromosome 2, complementation group b, l(2)EMS45-72, l(2)EMS4-72, E-2b" IPR002675=Ribosomal protein L38e CG18001 16-Dec-15 2015_12 ENSDARG00000006413(rpl38) YLR325C(RPL38) WBGene00004452(rpl-38) ENSXETG00000025319(rpl38) ENSMUSG00000057322(Rpl38) ENSG00000172809(RPL38) "lethal,developmental rate defective,Minute,dominant,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,increased cell size,decreased cell number,recessive" "prothoracic gland,chaeta,wing vein,ectopic,wing,wing hair,wing margin" DRSC07818 IE -2.199442934 -1.515981937 -0.263835024 -4.066607364 0.843777269 1.449596649 FBgn0053679 CG33679 http://flybase.net/reports/FBgn0053679.html FBgn0082903 protein_coding_gene "BP1003, unnamed" IPR010512=Protein of unknown function DUF1091 CG33679 16-Dec-15 2015_12 FBgn0065894 l(2)SH0213 lethal (2) SH0213 http://flybase.net/reports/FBgn0065894.html gene l(2)SH2 0213 16-Dec-15 2015_12 "lethal,recessive" FBgn0035186 CG13912 http://flybase.net/reports/FBgn0035186.html protein_coding_gene CG13912 16-Dec-15 2015_12 viable FBgn0053480 CG33480 http://flybase.net/reports/FBgn0053480.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033304 Cyp6a13 Cyp6a13 http://flybase.net/reports/FBgn0033304.html protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" "0042742=defense response to bacterium, 0055114=oxidation-reduction process" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG2397, cyp6a13, 6a13, cytochrome P450" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG2397 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "viable,fertile" FBgn0051708 DIP-ë¦ Dpr-interacting protein ë¦ http://flybase.net/reports/FBgn0051708.html "FBgn0032091, FBgn0032092, FBgn0032093" protein_coding_gene "CT32337, CG31708, DIP-zeta, CG13105, 31078, CG13104, CG13103, CT32338, CG31078" "IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set" CG31708 16-Dec-15 2015_12 WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02204 IE 1.129054264 -2.455230506 1.574180181 1.700076426 0.178792256 -0.648791747 FBgn0039311 CG10513 http://flybase.net/reports/FBgn0039311.html protein_coding_gene CT29500 "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG10513 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0003588 Su(var)2-8 Suppressor of variegation 2-8 http://flybase.net/reports/FBgn0003588.html gene "Su-var, Su-var(2)8, Su2" 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0004164 fs(2)sun female sterile (2) supernova http://flybase.net/reports/FBgn0004164.html gene "sun, supernova" 16-Dec-15 2015_12 female sterile FBgn0015036 Cyp4ae1 Cytochrome P450-4ae1 http://flybase.net/reports/FBgn0015036.html FBgn0014088 protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "I, P-450, Cypae1, Cyp4e4, CG10755, TcD20, anon-2Ea, EG:152A3.6, CYP4E4, 4ae1, P450, transcription unit I" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG10755 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0040211 hgo "homogentisate 1,2-dioxygenase" http://flybase.net/reports/FBgn0040211.html FBgn0032349 protein_coding_gene "0004411=homogentisate 1,2-dioxygenase activity" "0006559=L-phenylalanine catabolic process, 0006570=tyrosine metabolic process, 0055114=oxidation-reduction process, 0006572=tyrosine catabolic process" CG4779 "IPR005708=Homogentisate 1,2-dioxygenase, IPR014710=RmlC-like jelly roll fold, IPR011051=RmlC-like cupin domain" CG4779 16-Dec-15 2015_12 ENSDARG00000058005(hgd) WBGene00001843(hgo-1) ENSXETG00000009916(HGD) ENSMUSG00000022821(Hgd) "ENSG00000215729,ENSG00000113924(HGD)" viable FBgn0038157 CG12538 http://flybase.net/reports/FBgn0038157.html protein_coding_gene CG12538 16-Dec-15 2015_12 viable DRSC14527 E 0.046437574 0.110228914 -0.08017396 2.479050407 0.728833408 0.372081463 FBgn0085190 CG34161 http://flybase.net/reports/FBgn0085190.html protein_coding_gene 0003998=acylphosphatase activity "IPR001792=Acylphosphatase-like domain, IPR017968=Acylphosphatase, conserved site, IPR020456=Acylphosphatase" CG34161 16-Dec-15 2015_12 ENSDARG00000060126(acyp1) ENSXETG00000013250(acyp1) ENSMUSG00000008822(Acyp1) ENSG00000119640(ACYP1) FBgn0069111 mus219 mutagen-sensitive 219 http://flybase.net/reports/FBgn0069111.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0085244 CG34215 http://flybase.net/reports/FBgn0085244.html protein_coding_gene IPR029277=Single domain Von Willebrand factor type C domain CG34215 16-Dec-15 2015_12 FBgn0000641 fc faulty chaetae http://flybase.net/reports/FBgn0000641.html gene 16-Dec-15 2015_12 "visible,viable,fertile,recessive" "macrochaeta,scutellar bristle" FBgn0261728 EC666 http://flybase.net/reports/FBgn0261728.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0030132 CG12067 http://flybase.net/reports/FBgn0030132.html protein_coding_gene 16-Dec-15 2015_12 FBgn0023474 alm almond http://flybase.net/reports/FBgn0023474.html gene 16-Dec-15 2015_12 visible pigment cell FBgn0039740 ZIPIC Zinc-finger protein interacting with CP190 http://flybase.net/reports/FBgn0039740.html protein_coding_gene "0043035=chromatin insulator sequence binding, 0005515=protein binding, 0046872=metal ion binding, 0003682=chromatin binding, 0043565=sequence-specific DNA binding, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated" 0005700=polytene chromosome CG7928 "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7928 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0266689 CR45179 http://flybase.net/reports/FBgn0266689.html non_protein_coding_gene CR45179 16-Dec-15 2015_12 FBgn0262149 CR42875 http://flybase.net/reports/FBgn0262149.html non_protein_coding_gene CR42875 16-Dec-15 2015_12 FBgn0060437 l(3)S125011 lethal (3) S125011 http://flybase.net/reports/FBgn0060437.html gene 1250/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0014072 TART-element\pol TART-open reading frame 2 http://flybase.net/reports/FBgn0014072.html transposable_element_gene "RT, TART-RT, TART ORF2, reverse transcriptase, TART-repeat\ORF2, TART-element\ORF2, ORF2" "IPR000477=Reverse transcriptase domain, IPR005135=Endonuclease/exonuclease/phosphatase" 16-Dec-15 2015_12 FBgn0004774 l(3)91Cd lethal (3) 91Cd http://flybase.net/reports/FBgn0004774.html gene l(3)CR3 16-Dec-15 2015_12 lethal FBgn0039039 lmd lame duck http://flybase.net/reports/FBgn0039039.html FBgn0019860 protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007519=skeletal muscle tissue development, 0007517=muscle organ development, 0010817=regulation of hormone levels, 0007520=myoblast fusion, 0006355=regulation of transcription, DNA-templated, 0007525=somatic muscle development" "0005737=cytoplasm, 0005634=nucleus" "CG4677, anon-EST:CL2d4, minc, Myoblasts incompetent, Gleeful, gfl, unnamed, lameduck, Lmd, Lameduck, Lame duck, LMD, myoblasts incompetent, Lame Duck, K, gleeful" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG4677 16-Dec-15 2015_12 embryonic stage | late mesoderm

"lethal,viable,visible" "embryonic somatic muscle,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,embryonic/larval pericardial cell,supernumerary,muscle founder cell,embryonic myoblast,pharyngeal muscle,embryonic visceral muscle,trichogen cell" FBgn0015463 l(2)37Dk lethal (2) 37Dk http://flybase.net/reports/FBgn0015463.html gene "l(2)E144,M" 16-Dec-15 2015_12 "lethal,recessive" FBgn0037737 Pnn Pinin http://flybase.net/reports/FBgn0037737.html protein_coding_gene "0000398=mRNA splicing, via spliceosome, 0006396=RNA processing" "0071011=precatalytic spliceosome, 0030057=desmosome, 0071013=catalytic step 2 spliceosome" "pinin, CG8383, dPnn, FBgn0037737, Pinin" IPR006786=Pinin/SDK/MemA protein CG8383 16-Dec-15 2015_12 WBGene00011308(R186.7) viable FBgn0260316 GSd479 http://flybase.net/reports/FBgn0260316.html gene 16-Dec-15 2015_12 lethal FBgn0053811 His-ë¬:CR33811 His-ë¬:CR33811 http://flybase.net/reports/FBgn0053811.html pseudogene_attribute CR33811 CR33811 16-Dec-15 2015_12 FBgn0028024 l(3)S103616 lethal (3) S103616 http://flybase.net/reports/FBgn0028024.html gene 1036/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0003369 sg shortened wing http://flybase.net/reports/FBgn0003369.html gene 16-Dec-15 2015_12 "wing,wing vein" FBgn0261363 PPO3 Prophenoloxidase 3 http://flybase.net/reports/FBgn0261363.html "FBgn0000487, FBgn0034815" protein_coding_gene "0036264=dopamine monooxygenase activity, 0036263=L-DOPA monooxygenase activity" "0042417=dopamine metabolic process, 0008152=metabolic process" "CG2952, PPO3, Dox-A3, CG42640, ProPO59, prophenoloxidase 59, Diphenol OxidaseA3, proPO59, Pro-PO3, DmePPO3" "IPR002227=Tyrosinase copper-binding domain, IPR005204=Hemocyanin, N-terminal, IPR005203=Hemocyanin, C-terminal, IPR013788=Hemocyanin/hexamerin, IPR008922=Uncharacterised domain, di-copper centre, IPR014756=Immunoglobulin E-set, IPR000896=Hemocyanin/hexamerin middle domain" CG42640 16-Dec-15 2015_12 "melanotic mass phenotype,viable" melanotic mass FBgn0040567 CG12332 http://flybase.net/reports/FBgn0040567.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002641 mal maroon-like http://flybase.net/reports/FBgn0002641.html protein_coding_gene "0008265=Mo-molybdopterin cofactor sulfurase activity, 0030170=pyridoxal phosphate binding, 0030151=molybdenum ion binding" "0006727=ommochrome biosynthetic process, 0006777=Mo-molybdopterin cofactor biosynthetic process, 0043545=molybdopterin cofactor metabolic process" "ma-l, bz, CG1692, section 5, 5, SRF, bronzy, maroonlike" "IPR005302=Molybdenum cofactor sulfurase, C-terminal, IPR005303=MOSC, N-terminal beta barrel, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR028886=Molybdenum cofactor sulfurase, IPR000192=Aminotransferase class V domain, IPR011037=Pyruvate kinase-like, insert domain" CG1692 16-Dec-15 2015_12 ENSDARG00000057148 WBGene00010983(R03A10.3) ENSMUSG00000039616(Mocos) ENSG00000075643(MOCOS) "viable,fertile,eye color defective,male fertile,male,male sterile,chemical sensitive,recessive" "pigment cell,Malpighian tubule" FBgn0037431 CG17917 http://flybase.net/reports/FBgn0037431.html protein_coding_gene "IPR001858=Phosphatidylethanolamine-binding, conserved site, IPR008914=Phosphatidylethanolamine-binding protein PEBP" CG17917 16-Dec-15 2015_12 "YLR179C(),YLR178C(TFS1)" "viable,fertile" FBgn0035434 Drsl5 Drosomycin-like 5 http://flybase.net/reports/FBgn0035434.html FBgn0063260 protein_coding_gene "0006952=defense response, 0050832=defense response to fungus" 0005576=extracellular region "Drosomycin-like G, Drosomycin B, dmy5, Drosomycin 5, Dro-G, BcDNA:GH09576, dro5, Drosomycin-5, drosomycin-5, drosomycin-G, Dro5, drosomycin, Drs-lG, CG10812, drosmycin-5" "IPR003614=Knottin, scorpion toxin-like" CG10812 16-Dec-15 2015_12 viable FBgn0052039 CG32039 http://flybase.net/reports/FBgn0052039.html "FBgn0045835, FBgn0063077" protein_coding_gene "BcDNA:RE03722, BEST:GH02734" CG32039 16-Dec-15 2015_12 ENSG00000198168(SVIP) viable FBgn0022222 l(2)k03205 lethal (2) k03205 http://flybase.net/reports/FBgn0022222.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262552 Mod(GMroX1)149 http://flybase.net/reports/FBgn0262552.html gene 16-Dec-15 2015_12 FBgn0266307 CR44972 http://flybase.net/reports/FBgn0266307.html non_protein_coding_gene CR44972 16-Dec-15 2015_12 FBgn0035806 PGRP-SD PGRP-SD http://flybase.net/reports/FBgn0035806.html protein_coding_gene "0008270=zinc ion binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0042834=peptidoglycan binding" "0006955=immune response, 0050830=defense response to Gram-positive bacterium, 0009253=peptidoglycan catabolic process, 0006952=defense response" "0005887=integral component of plasma membrane, 0005576=extracellular region" "CG7496, Dm PGRP-SD, Peptidoglycan-recognition protein-SD precursor, pgrp-sd" "IPR015510=Peptidoglycan recognition protein, IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR017331=Peptidoglycan recognition protein, PGRP-S, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria" CG7496 16-Dec-15 2015_12 "viable,fertile,immune response defective" FBgn0013492 l(1)90 lethal (1) 90 http://flybase.net/reports/FBgn0013492.html gene l90 16-Dec-15 2015_12 "lethal,recessive" FBgn0267719 CR46052 http://flybase.net/reports/FBgn0267719.html non_protein_coding_gene CR46052 16-Dec-15 2015_12 FBgn0000625 eyg eyegone http://flybase.net/reports/FBgn0000625.html FBgn0011647 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0001654=eye development, 0007477=notum development, 0048749=compound eye development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0001745=compound eye morphogenesis, 0007469=antennal development, 0035214=eye-antennal disc development, 0007435=salivary gland morphogenesis" "0005667=transcription factor complex, 0005634=nucleus" "Eygone, eyeone, lune, CG10488, Eyg, Bk27, Eyegone, BK27, eye gone, EYG, lun, eygone" "IPR001523=Paired domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG10488 16-Dec-15 2015_12 "WBGene00001204(egl-38),WBGene00003938(pax-2)" " embryonic stage , larval stage | third instar , embryonic stage | stage >=11 , larval stage | second instar-- L | third instar " " adult eye primordium

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, salivary gland body primordium

, eye disc

, embryonic head | restricted

, eye disc | dorsal && morphogenetic furrow | anterior to

, eye disc | anterior

, antennal disc | central

, embryonic/larval posterior spiracle | vicinity of

, epidermis | segmentally repeated

" larval stage | third instar dorsal mesothoracic disc | restricted

"lethal,recessive,cell growth defective,somatic clone,lethal - all die before end of pupal stage,visible,some die during pupal stage,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,semidominant,partially lethal - majority die,increased cell death,planar polarity defective,hyperplasia" "thorax,eye disc,eye-antennal disc,head,cell non-autonomous,somatic clone,eye,retina,adult head,adult thorax,dorsocentral bristle,mesothoracic tergum,microchaeta,embryonic/larval salivary gland duct,salivary gland imaginal ring,photoreceptor cell,ectopic,ventral,eye | pharate adult stage,thorax | pharate adult stage,supernumerary,wing disc,head | pharate adult stage,scutum,scutellum,macrochaeta,macrochaeta & scutumMS248,macrochaeta & scutum455.2,macrochaeta & scutumush-MD751,macrochaeta & scutumpnr-MD237,macrochaeta & scutumMD-638,wing,adult cuticle,proximal,heat sensitive,trichogen cell" FBgn0037251 CG9804 http://flybase.net/reports/FBgn0037251.html FBan0009804 protein_coding_gene "0033819=lipoyl(octanoyl) transferase activity, 0016979=lipoate-protein ligase activity, 0016415=octanoyltransferase activity" "0009107=lipoate biosynthetic process, 0009249=protein lipoylation" 0005737=cytoplasm "IPR020605=Octanoyltransferase, conserved site, IPR004143=Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain, IPR000544=Octanoyltransferase" CG9804 16-Dec-15 2015_12 ENSDARG00000069852(zgc:136925) YLR239C(LIP2) ENSXETG00000006379(LIPT2) ENSMUSG00000030725(Lipt2) ENSG00000175536(LIPT2) viable FBgn0066122 E(sda)M E(sda)M http://flybase.net/reports/FBgn0066122.html gene Line M 16-Dec-15 2015_12 FBgn0004193 snRNA:U2:84Ca small nuclear RNA U2 at 84Ca http://flybase.net/reports/FBgn0004193.html "FBgn0003919, FBgn0003924" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0015030=Cajal body "U2 snRNA, dU2, small nuclear RNA U2, snRNA:U2, U2, U2snRNA, U2snRNA84Ca" 16-Dec-15 2015_12 FBgn0065531 l(2)SH1108 lethal (2) SH1108 http://flybase.net/reports/FBgn0065531.html gene l(2)SH2 1108 16-Dec-15 2015_12 "lethal,recessive" FBgn0045054 fs(1)217 female sterile (1) 217 http://flybase.net/reports/FBgn0045054.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "egg chamber,follicle cell" FBgn0037899 RpL24-like Ribosomal protein L24-like http://flybase.net/reports/FBgn0037899.html protein_coding_gene 0003735=structural constituent of ribosome "0040018=positive regulation of multicellular organism growth, 0042254=ribosome biogenesis, 0006412=translation" 0022625=cytosolic large ribosomal subunit CG6764 "IPR024546=Ribosome biogenesis protein RLP24, IPR000988=Ribosomal protein L24e-related, IPR011017=TRASH domain, IPR023442=Ribosomal protein L24e, conserved site, IPR023441=Ribosomal protein L24e domain" CG6764 16-Dec-15 2015_12 ENSDARG00000040439(rsl24d1) YLR009W(RLP24) WBGene00004437(rpl-24.2) ENSXETG00000007376(RSL24D1) "ENSMUSG00000053740(Gm6457),ENSMUSG00000032215(Rsl24d1)" ENSG00000137876(RSL24D1) FBgn0260661 U5-40k http://flybase.net/reports/FBgn0260661.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266844 CR45306 http://flybase.net/reports/FBgn0266844.html non_protein_coding_gene CR45306 16-Dec-15 2015_12 FBgn0065393 l(2)SH1625 lethal (2) SH1625 http://flybase.net/reports/FBgn0065393.html gene l(2)SH2 1625 16-Dec-15 2015_12 "lethal,recessive" FBgn0044472 EP1592 EP1592 http://flybase.net/reports/FBgn0044472.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0013999 Op29 Ovary protein-29kD http://flybase.net/reports/FBgn0013999.html gene 0005921=gap junction Dop29 16-Dec-15 2015_12 oogenesis stage && adult stage | female ovary

FBgn0082375 EP1457 EP1457 http://flybase.net/reports/FBgn0082375.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0264420 FCO-E http://flybase.net/reports/FBgn0264420.html gene 16-Dec-15 2015_12 "increased cell death,somatic clone" "follicle cell,somatic clone" FBgn0044406 Scim21 Sensitized chromosome inheritance modifier 21 http://flybase.net/reports/FBgn0044406.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0032974 CG3651 http://flybase.net/reports/FBgn0032974.html FBan0003651 protein_coding_gene CG3651 16-Dec-15 2015_12 viable FBgn0027775 anon-69Da anon-69Da http://flybase.net/reports/FBgn0027775.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0027207 l(1)G0394 lethal (1) G0394 http://flybase.net/reports/FBgn0027207.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0013567 l(3)78Ac lethal (3) 78Ac http://flybase.net/reports/FBgn0013567.html gene 16-Dec-15 2015_12 lethal FBgn0053548 msta msta http://flybase.net/reports/FBgn0053548.html "FBgn0023547, FBgn0023548, FBgn0052799, FBgn0052800" protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression "EG:103B4.4, EG:103B4.5, Msta, MSTA, CG18033, CG33548, CG32799, CG32800" IPR001214=SET domain CG33548 16-Dec-15 2015_12 viable FBgn0267770 CR46101 http://flybase.net/reports/FBgn0267770.html non_protein_coding_gene CR46101 16-Dec-15 2015_12 FBgn0033708 CG8850 http://flybase.net/reports/FBgn0033708.html protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005416=cation:amino acid symporter activity, 0017032=potassium:amino acid symporter activity, 0005326=neurotransmitter transporter activity" "0006836=neurotransmitter transport, 0044745=amino acid transmembrane import" 0016021=integral component of membrane DmNAT4 IPR000175=Sodium:neurotransmitter symporter CG8850 16-Dec-15 2015_12 FBgn0063780 accord2\pol pol http://flybase.net/reports/FBgn0063780.html transposable_element_gene qbert\pol IPR000477=Reverse transcriptase domain 16-Dec-15 2015_12 FBgn0030107 CG15370 http://flybase.net/reports/FBgn0030107.html protein_coding_gene CG15370 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0005436 l(1)v47 lethal (1) v47 http://flybase.net/reports/FBgn0005436.html gene l(1)47 16-Dec-15 2015_12 FBgn0086718 aga angina http://flybase.net/reports/FBgn0086718.html gene 16-Dec-15 2015_12 FBgn0060417 l(3)S129310b lethal (3) S129310b http://flybase.net/reports/FBgn0060417.html gene 1293/10 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0016947 tilD touch insensitive larva D http://flybase.net/reports/FBgn0016947.html gene 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective,visible,somatic clone,paralytic" "macrochaeta,somatic clone,leg" FBgn0017423 anon-70Ca anon-70Ca http://flybase.net/reports/FBgn0017423.html gene t2 16-Dec-15 2015_12 " embryonic stage&&larval stage && pupal stage , egg stage | unfertilized egg " unfertilized egg

FBgn0038673 CG14286 http://flybase.net/reports/FBgn0038673.html protein_coding_gene 14286 IPR029274=Protein of unknown function DUF4615 CG14286 16-Dec-15 2015_12 ENSDARG00000038556(zgc:112185) ENSXETG00000024441(C8orf33) ENSMUSG00000063236(1110038F14Rik) ENSG00000182307(C8orf33) "viable,fertile" FBgn0060694 l(3)S073015 lethal (3) S073015 http://flybase.net/reports/FBgn0060694.html gene 0730/15 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0067866 Mod(Prat:bw)3-9 Mod(Prat:bw)3-9 http://flybase.net/reports/FBgn0067866.html gene Mod-3-9 16-Dec-15 2015_12 "female sterile,recessive" FBgn0004623 Gë_76C G protein ë_-subunit 76C http://flybase.net/reports/FBgn0004623.html FBgn0016651 protein_coding_gene "0003924=GTPase activity, 0046982=protein heterodimerization activity" "0007202=activation of phospholipase C activity, 0007186=G-protein coupled receptor signaling pathway, 0007602=phototransduction, 0016056=rhodopsin mediated signaling pathway, 0016059=deactivation of rhodopsin mediated signaling" "0005834=heterotrimeric G-protein complex, 0005737=cytoplasm, 0016028=rhabdomere, 0005886=plasma membrane" "Gbeta76C, Gbeta[[e]], Gbetae, G protein beta-subunit 76C, G[q], G[[beta]], gbe, G&bgr76C, Galpha76C, Gqbeta, eye Gbeta, Gbeta{e}, Gbeta76c, CG8770, G[[beta76C]], DGqbeta, G[[beta]] eye, G[[beta]]e, Gbe, eGbeta, Gbeta, guanine nucleotide regulatory protein beta subunit" "IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001632=G-protein, beta subunit, IPR016346=Guanine nucleotide-binding protein, beta subunit, IPR001680=WD40 repeat" CG8770 16-Dec-15 2015_12 YOR212W(STE4) adult stage " adult head

, eye

" adult stage " eye

, photoreceptor cell

, medulla

, lamina

" "wild-type,neurophysiology defective,viable" photoreceptor cell FBgn0051365 CG31365 http://flybase.net/reports/FBgn0051365.html FBgn0039057 protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus CG4639 "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG31365 16-Dec-15 2015_12 "WBGene00003087(lsy-2),WBGene00009937(lsl-1)" viable FBgn0060358 l(3)S140612 lethal (3) S140612 http://flybase.net/reports/FBgn0060358.html gene 1406/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0039681 CG7582 http://flybase.net/reports/FBgn0039681.html protein_coding_gene 0016021=integral component of membrane IPR012506=YhhN-like CG7582 16-Dec-15 2015_12 ENSDARG00000044034(tmem86a) WBGene00010943(M176.4) ENSMUSG00000010307(Tmem86a) ENSG00000151117(TMEM86A) viable FBgn0259196 CG42300 http://flybase.net/reports/FBgn0259196.html "FBan0032584, FBgn0052584" protein_coding_gene 0019789=SUMO transferase activity 0000724=double-strand break repair via homologous recombination 0030915=Smc5-Smc6 complex "CG32584, CG18620" IPR026846=E3 SUMO-protein ligase Nse2 (Mms21) CG42300 16-Dec-15 2015_12 WBGene00022881(ZK1248.11) ENSMUSG00000059586(Nsmce2) ENSG00000156831(NSMCE2) "viable,visible,fertile" tormogen cell FBgn0030932 Ggt-1 ë_-glutamyl transpeptidase http://flybase.net/reports/FBgn0030932.html protein_coding_gene 0003840=gamma-glutamyltransferase activity "0032504=multicellular organism reproduction, 0009416=response to light stimulus, 0006749=glutathione metabolic process" 0005615=extracellular space "CG6461, GGT-1, gamma-glutamyl transpeptidase, gamma-glutamyl transferase, Ggt-1" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000101=Gamma-glutamyltranspeptidase" CG6461 16-Dec-15 2015_12 "ENSDARG00000023526(ggt1),ENSDARG00000018342(LOC569014),ENSDARG00000013504,ENSDARG00000040592" YLR299W(ECM38) "WBGene00011393(T03D8.6),WBGene00019204(H14N18.4),WBGene00012416(Y7A9A.1)" ENSXETG00000004232(BC075461.1) ENSMUSG00000006345(Ggt1) "ENSG00000100031(GGT1),ENSG00000197421,ENSG00000133475(GGT2),ENSG00000216522" partially lethal - majority die FBgn0024638 l(2)k13525 lethal (2) k13525 http://flybase.net/reports/FBgn0024638.html gene 135/25 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0036705 CG13723 http://flybase.net/reports/FBgn0036705.html protein_coding_gene CG13723 16-Dec-15 2015_12 viable FBgn0036317 CG10948 http://flybase.net/reports/FBgn0036317.html protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" "CT30663, cg10948" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG10948 16-Dec-15 2015_12 ENSXETG00000014586(ENOX1) "ENSMUSG00000022012(Enox1),ENSMUSG00000031109(Enox2)" "ENSG00000165675(ENOX2),ENSG00000120658(ENOX1)" "fertile,viable,lethal,partially lethal - majority die" FBgn0005651 Mst59Da Male-specific transcript 59Da http://flybase.net/reports/FBgn0005651.html gene 16-Dec-15 2015_12 FBgn0043996 Su(rst)D121 Su(rst)D121 http://flybase.net/reports/FBgn0043996.html gene 0001745=compound eye morphogenesis D121 16-Dec-15 2015_12 viable eye FBgn0070041 3R-35-29 3R-35-29 http://flybase.net/reports/FBgn0070041.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0000773 fs(1)A1187 female sterile (1) A1187 http://flybase.net/reports/FBgn0000773.html gene fs(1)1187 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,heat sensitive,female sterile,recessive,mitotic cell cycle defective" blastoderm embryo FBgn0005300 mei-O81 meiotic from Ostiense 81 http://flybase.net/reports/FBgn0005300.html gene 0007140=male meiosis 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive" spermatocyte & nuclear chromosome FBgn0043992 Su(rst)D49 Su(rst)D49 http://flybase.net/reports/FBgn0043992.html gene 0001745=compound eye morphogenesis D49 16-Dec-15 2015_12 viable FBgn0028550 Atf3 Activating transcription factor 3 http://flybase.net/reports/FBgn0028550.html FBgn0026877 protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0005515=protein binding" "0006955=immune response, 0006357=regulation of transcription from RNA polymerase II promoter, 0007399=nervous system development, 0055088=lipid homeostasis" 0005634=nucleus "Atf3, EG:33C11.1, DM11, atf3, CG11405, A3-3, ATF3, dATF3, Activating transcription factor 3" "IPR000837=AP-1 transcription factor, IPR004827=Basic-leucine zipper domain" CG11405 16-Dec-15 2015_12 "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,lethal,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,female fertile,reduced,partially,recessive" "eye,adult cuticle,dorsal,adult abdomen,somatic clone,embryonic/larval fat body,lipid particle" FBgn0058464 CR40464 http://flybase.net/reports/FBgn0058464.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0044459 EP3373 EP3373 http://flybase.net/reports/FBgn0044459.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0052546 tRNA:CR32546 transfer RNA:CR32546 http://flybase.net/reports/FBgn0052546.html FBgn0060118 tRNA_gene 0033424=CCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chrX.trna14-ProCGG, CR32546, AE002593.trna10-ProCGG, tRNA:P:CGG:AE002593" CR32546 16-Dec-15 2015_12 FBgn0260125 2L3574 http://flybase.net/reports/FBgn0260125.html gene 16-Dec-15 2015_12 FBgn0030678 CG11679 http://flybase.net/reports/FBgn0030678.html protein_coding_gene IPR003734=Protein of unknown function DUF155 CG11679 16-Dec-15 2015_12 ENSDARG00000027465(rmnd1) "YDL001W(RMD1),YFR048W(RMD8)" WBGene00014176(ZK1010.2) ENSMUSG00000019763(Rmnd1) ENSG00000155906(RMND1) "viable,body color defective" mesothoracic tergum FBgn0052305 CG32305 http://flybase.net/reports/FBgn0052305.html FBgn0035320 protein_coding_gene 0004016=adenylate cyclase activity "0006171=cAMP biosynthetic process, 0035556=intracellular signal transduction" 0016021=integral component of membrane "CG8970, AC" "IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG32305 16-Dec-15 2015_12 viable FBgn0002188 l(3)63Aa lethal (3) 63Aa http://flybase.net/reports/FBgn0002188.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0030035 CG11190 http://flybase.net/reports/FBgn0030035.html protein_coding_gene 0016255=attachment of GPI anchor to protein "0005783=endoplasmic reticulum, 0042765=GPI-anchor transamidase complex" Dm*AAF46367/27-522 IPR007245=GPI transamidase component PIG-T CG11190 16-Dec-15 2015_12 YHR188C(GPI16) WBGene00008918(F17C11.7) ENSXETG00000021432(Q499W8_XENTR) ENSMUSG00000017721(Pigt) ENSG00000124155(PIGT) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015771 N::tor N::tor http://flybase.net/reports/FBgn0015771.html engineered_fusion_gene 16-Dec-15 2015_12 visible "microchaeta,precursor,wing disc" FBgn0030457 CG12096 http://flybase.net/reports/FBgn0030457.html protein_coding_gene "0043248=proteasome assembly, 0006974=cellular response to DNA damage stimulus" "dS5b, S5b/PSMD5, 12096, S5b" "IPR016024=Armadillo-type fold, IPR019538=26S proteasome non-ATPase regulatory subunit 5" CG12096 16-Dec-15 2015_12 ENSDARG00000059046(zgc:110116) ENSXETG00000019595(PSMD5) ENSMUSG00000026869(Psmd5) ENSG00000095261(PSMD5) "viable,fertile" FBgn0262455 mir-1 mir-1 stem loop http://flybase.net/reports/FBgn0262455.html "FBgn0046834, FBgn0262320" miRNA_gene "0035195=gene silencing by miRNA, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0035051=cardiocyte differentiation, 0046716=muscle cell cellular homeostasis, 0008593=regulation of Notch signaling pathway" "dme-mir-1, transfrag 8, dmiR-1, MiR-1, miR-1, CR43027, dme-miR-1-3p, DmiR-1, Mir-1, Mir1, mir-1, miR1, mirR-1, CR32958" CR43027 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0022983 rdgB::Rnor\PITPNA rdgB::Rnor\PITPNA http://flybase.net/reports/FBgn0022983.html engineered_fusion_gene rdgB::Rat\PITPNA 16-Dec-15 2015_12 "rhabdomere R5,rhabdomere R6,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4" FBgn0085616 CG41326 http://flybase.net/reports/FBgn0085616.html FBan0041326 protein_coding_gene 16-Dec-15 2015_12 FBgn0004128 l(2)43Cb lethal (2) 43Cb http://flybase.net/reports/FBgn0004128.html FBgn0014246 gene 43Cb 16-Dec-15 2015_12 lethal FBgn0052163 CG32163 http://flybase.net/reports/FBgn0052163.html protein_coding_gene "IPR031165=Yjdj-type Gcn5-related N-acetyltransferase, IPR016181=Acyl-CoA N-acyltransferase" CG32163 16-Dec-15 2015_12 viable DRSC21888 EK -1.004865896 0.362191192 3.828094224 0.167604634 -0.16325746 -1.502401665 FBgn0042198 CG16741 http://flybase.net/reports/FBgn0042198.html FBgn0040728 protein_coding_gene CG18463 CG16741 16-Dec-15 2015_12 viable FBgn0004512 Mdr49 Multi drug resistance 49 http://flybase.net/reports/FBgn0004512.html protein_coding_gene "0015238=drug transmembrane transporter activity, 0042623=ATPase activity, coupled, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005524=ATP binding" "0006855=drug transmembrane transport, 0008354=germ cell migration, 0015893=drug transport, 0055085=transmembrane transport, 0031427=response to methotrexate, 0001666=response to hypoxia" "0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "Dm5, CG3879, mdr49, Mes5, mrd49, MDR49, MDR5" "IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR011527=ABC transporter type 1, transmembrane domain" CG3879 16-Dec-15 2015_12 YKL209C(STE6) embryonic stage | cellular blastoderm mesoderm anlage

viable "germline cell,pole cell" FBgn0086418 l(3)CHb lethal (3) CHb http://flybase.net/reports/FBgn0086418.html gene complementation group 4 16-Dec-15 2015_12 "lethal,recessive" FBgn0020297 jockey\gag jockey gag http://flybase.net/reports/FBgn0020297.html transposable_element_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" Jockey ORF1 "IPR001878=Zinc finger, CCHC-type, IPR006579=Pre-C2HC domain" 16-Dec-15 2015_12 FBgn0262333 mir-963 mir-963 stem loop http://flybase.net/reports/FBgn0262333.html miRNA_gene "0006955=immune response, 0060259=regulation of feeding behavior" "CR43040, dme-mir-963, miR-963" CR43040 16-Dec-15 2015_12 "visible,lethal" wing FBgn0019929 Ser7 Ser7 http://flybase.net/reports/FBgn0019929.html FBgn0030154 protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis "SP#2, SP3, SP2, c-SP3, Serine Protease 2, CG2045" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG2045 16-Dec-15 2015_12 viable FBgn0085679 CG41542 http://flybase.net/reports/FBgn0085679.html FBan0041542 protein_coding_gene 16-Dec-15 2015_12 FBgn0052506 CG32506 http://flybase.net/reports/FBgn0052506.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity "IPR004012=RUN domain, IPR000195=Rab-GTPase-TBC domain" CG32506 16-Dec-15 2015_12 "ENSDARG00000028857(LOC794373),ENSDARG00000063307" WBGene00008018(tbc-8) "ENSXETG00000018672(SGSM1),ENSXETG00000019436(SGSM2)" ENSMUSG00000042216(Sgsm1) ENSG00000167037(SGSM1) "viable,fertile" FBgn0025627 CG4194 http://flybase.net/reports/FBgn0025627.html protein_coding_gene EG:22E5.6 CG4194 16-Dec-15 2015_12 FBgn0002183 dre4 dre4 http://flybase.net/reports/FBgn0002183.html FBgn0002182 protein_coding_gene "0003682=chromatin binding, 0031491=nucleosome binding, 0003677=DNA binding" "0006268=DNA unwinding involved in DNA replication, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0022008=neurogenesis, 0001672=regulation of chromatin assembly or disassembly" "0005634=nucleus, 0035101=FACT complex" "supressor of Ty element 16, l(3)62Bg, dSpt16, dspt16, DRE4/dSPT16, Dre4, Spt16, lethal(3)62Bg, l(3)dre4, SPT16, dSPT16, spt16, CG1828" "IPR013953=FACT complex subunit Spt16p/Cdc68p, IPR000994=Peptidase M24, structural domain, IPR029149=Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR029148=FACT complex subunit Spt16, N-terminal lobe domain, IPR013719=Domain of unknown function DUF1747" CG1828 16-Dec-15 2015_12 YGL207W(SPT16) WBGene00018849(F55A3.3) ENSXETG00000017204(SUPT16H) ENSMUSG00000035726(Supt16h) ENSG00000092201(SUPT16H) "lethal,heat sensitive,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC08714 I -3.721266813 -1.380521877 -0.547079818 -0.614702853 -1.109159874 0.284282458 FBgn0046665 anon-38C.32 anon-38C.32 http://flybase.net/reports/FBgn0046665.html gene 38C.32 16-Dec-15 2015_12 FBgn0002617 M(3)76A Minute (3) 76A http://flybase.net/reports/FBgn0002617.html gene M(3)S34 16-Dec-15 2015_12 "lethal,recessive" FBgn0022323 l(1)B22.5 lethal (1) B22.5 http://flybase.net/reports/FBgn0022323.html gene B22.5 16-Dec-15 2015_12 "lethal,recessive" FBgn0039703 CG7829 http://flybase.net/reports/FBgn0039703.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP136 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG7829 16-Dec-15 2015_12 viable FBgn0085723 CG41616 http://flybase.net/reports/FBgn0085723.html FBan0041616 protein_coding_gene 16-Dec-15 2015_12 FBgn0264717 CR43985 http://flybase.net/reports/FBgn0264717.html non_protein_coding_gene CR43985 16-Dec-15 2015_12 FBgn0011106 l(1)Q67 lethal (1) Q67 http://flybase.net/reports/FBgn0011106.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0042157 CG18834 http://flybase.net/reports/FBgn0042157.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065233 l(2)SH2168 lethal (2) SH2168 http://flybase.net/reports/FBgn0065233.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261563 wb wing blister http://flybase.net/reports/FBgn0261563.html "FBgn0004002, FBgn0025691, FBgn0032544, FBgn0052970, FBgn0028885" protein_coding_gene "0008406=gonad development, 0007502=digestive tract mesoderm development, 0007476=imaginal disc-derived wing morphogenesis" "0005604=basement membrane, 0005605=basal lamina" "laminin, lethal group A1, SGP cluster fusion defects 5, CK02229, l(2)br1, laminin alpha[[1,2]], fus5, CG42677, A1, BG:DS03792.1, l34Fb, laminin alpha1,2, lethal 1 in the black-reduced region, CG32970, LM-A/alpha2, BG:DS03792.2, alpha laminin, l(2)09437, lamininW, DLAM, Laminin alpha1,2, &agr1,2Lan, Laminin A2, LanA1,2, LamininW, D-laminin alpha2, wing blistered, alpha[[1,2]], l(2)34Fb, CT35236, BEST:CK02229, CG15288" "IPR013032=EGF-like, conserved site, IPR008211=Laminin, N-terminal, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000034=Laminin IV, IPR002049=Laminin EGF domain" CG42677 16-Dec-15 2015_12 WBGene00002248(lam-3) ENSXETG00000004956(LAMA1) "ENSMUSG00000032796(Lama1),ENSMUSG00000019899(Lama2)" "ENSG00000101680(LAMA1),ENSG00000196569(LAMA2)" " embryonic stage | early , embryonic stage | stage >12 , embryonic stage | stage 14 , embryonic stage -- adult stage , embryonic stage | stage 9-11 , adult stage && oogenesis stage " "

ubiquitous , visceral mesoderm

, alary cell

, muscle attachment site | vicinity of

, oocyte

, nurse cell

" " larval stage | third instar , embryonic stage | stage >14 , embryonic stage | stage 14 , embryonic stage | stage 10 , embryonic stage | stage >=12 " " dorsal mesothoracic disc | restricted

, ventral nerve cord | dorsal

, muscle attachment site

, mesectoderm

, visceral mesoderm

" DRSC23003 K 1.318098992 1.740092199 FBgn0265697 CR44504 http://flybase.net/reports/FBgn0265697.html non_protein_coding_gene pri-mir-6-3_mir-6-2_mir-6-1_mir-5_mir-4_mir-286_mir-3_mir-309 CR44504 16-Dec-15 2015_12 FBgn0015828 TfIIEë± Transcription factor IIEë± http://flybase.net/reports/FBgn0015828.html protein_coding_gene 0043565=sequence-specific DNA binding "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0005673=transcription factor TFIIE complex, 0005634=nucleus" "TfIIE, TfIIEalpha, dTFIIE-L, TFIIE-L, TFIIE, TFIIEalpha, CG10415, TfIIEa, dTFIIEL" "IPR024550=TFIIEalpha/SarR/Rpc3 HTH domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017919=Transcription factor TFE/TFIIEalpha HTH domain, IPR021600=Transcription factor TFIIE alpha subunit, C-terminal, IPR002853=Transcription factor TFIIE, alpha subunit" CG10415 16-Dec-15 2015_12 ENSDARG00000000542(LOC100329411) YKL028W(TFA1) WBGene00013998(ZK550.4) "ENSXETG00000012462(),ENSXETG00000009918(GTF2E1)" ENSMUSG00000022828(Gtf2e1) ENSG00000153767(GTF2E1) lethal FBgn0086052 snoRNA:Me18S-G423 http://flybase.net/reports/FBgn0086052.html snoRNA_gene "CR34681, Me18S-Gm423" CR34681 16-Dec-15 2015_12 FBgn0060297 p74S p74S http://flybase.net/reports/FBgn0060297.html gene 0042169=SH2 domain binding p74 16-Dec-15 2015_12 FBgn0025733 sca::Hsap\FGB sca::Hsap\FGB http://flybase.net/reports/FBgn0025733.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0004857 elA elbow A http://flybase.net/reports/FBgn0004857.html FBgn0000569 gene "el, elbow, elb, el[A]" 16-Dec-15 2015_12 "visible,recessive,viable" "wing,posterior,wing vein L5,haltere,wing vein L4,alula,dorsal row,costal cell,wing vein L1" FBgn0260062 2L3547 http://flybase.net/reports/FBgn0260062.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0024752 Fs(2)1 Fs(2)1 http://flybase.net/reports/FBgn0024752.html gene 16-Dec-15 2015_12 "female sterile,female sterile germline-dependent,dominant,viable" "egg,dorsal appendage,nurse cell,chorion" FBgn0042148 CG18825 http://flybase.net/reports/FBgn0042148.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011635 l(2)T57h8 lethal (2) T57h8 http://flybase.net/reports/FBgn0011635.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0033248 Dic3 Dicarboxylate carrier 3 http://flybase.net/reports/FBgn0033248.html protein_coding_gene "0015117=thiosulfate transmembrane transporter activity, 0015140=malate transmembrane transporter activity, 0022857=transmembrane transporter activity, 0005315=inorganic phosphate transmembrane transporter activity, 0015116=sulfate transmembrane transporter activity" "0015709=thiosulfate transport, 0071423=malate transmembrane transport, 0008272=sulfate transport, 0035435=phosphate ion transmembrane transport, 0006839=mitochondrial transport" "0005739=mitochondrion, 0031966=mitochondrial membrane" "CG11196, Dic3p" "IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG11196 16-Dec-15 2015_12 ENSDARG00000025074(slc25a10) YLR348C(DIC1) "viable,body color defective" mesothoracic tergum FBgn0028012 l(3)S110013 lethal (3) S110013 http://flybase.net/reports/FBgn0028012.html gene 1100/13 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0032671 CG7200 http://flybase.net/reports/FBgn0032671.html protein_coding_gene IPR003347=JmjC domain CG7200 16-Dec-15 2015_12 ENSDARG00000058995(zgc:153974) WBGene00011563(T07C4.11) ENSXETG00000003687(JMJD4) ENSMUSG00000036819(Jmjd4) ENSG00000081692(JMJD4) viable FBgn0259371 C125 http://flybase.net/reports/FBgn0259371.html gene 16-Dec-15 2015_12 visible "wing hair,supernumerary,wing" FBgn0011619 l(1)K49c-A7 lethal (1) K49c-A7 http://flybase.net/reports/FBgn0011619.html gene 16-Dec-15 2015_12 lethal FBgn0005479 l(1)ts1107 lethal (1) ts1107 http://flybase.net/reports/FBgn0005479.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0023528 CG2924 http://flybase.net/reports/FBgn0023528.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0070936=protein K48-linked ubiquitination "EG:25E8.2, NICE5" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG2924 16-Dec-15 2015_12 ENSDARG00000013990(ube2q2) WBGene00006720(ubc-25) ENSXETG00000015330(TEgg045a15.1) "ENSMUSG00000032307(Ube2q2),ENSMUSG00000042572(Ube2q1),ENSMUSG00000045291" "ENSG00000140367(UBE2Q2),ENSG00000160714(UBE2Q1)" FBgn0030963 CG7101 http://flybase.net/reports/FBgn0030963.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG7101 16-Dec-15 2015_12 "viable,fertile" FBgn0001632 l(1)dn11 lethal (1) discs normal 11 http://flybase.net/reports/FBgn0001632.html gene l(1)d.norm.-11 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0042143 CG18820 http://flybase.net/reports/FBgn0042143.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035887 Jon66Cii Jonah 66Cii http://flybase.net/reports/FBgn0035887.html FBgn0001287 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP165, CG7170, chymotrypsin-type peptidase, Jon66C, Jonah 66C, 66C, CCG7170" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG7170 16-Dec-15 2015_12 "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0263037 CG43332 http://flybase.net/reports/FBgn0263037.html "FBgn0052972, FBan0032972, FBgn0028905" protein_coding_gene "CG32972, CG15291, BG:DS01523.2" CG43332 16-Dec-15 2015_12 FBgn0037354 CG12171 http://flybase.net/reports/FBgn0037354.html FBgn0061604 protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process anon-WO0118547.83 "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain" CG12171 16-Dec-15 2015_12 ENSDARG00000035129(zgc:101858) "YIR035C(),YIR036C(IRC24)" "WBGene00021647(Y47G6A.22),WBGene00021646(Y47G6A.21)" ENSXETG00000026045(BC076694.1) ENSMUSG00000030825(Hsd17b14) ENSG00000087076(HSD17B14) "viable,fertile" FBgn0085232 CG34203 http://flybase.net/reports/FBgn0085232.html protein_coding_gene CG34203 16-Dec-15 2015_12 FBgn0022150 l(2)k05911 lethal (2) k05911 http://flybase.net/reports/FBgn0022150.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000438 dfa deformed antennae http://flybase.net/reports/FBgn0000438.html gene 16-Dec-15 2015_12 "viable,female sterile,male fertile,visible" "wing,eye,macrochaeta,antenna,arista,trident" FBgn0036623 CG4729 http://flybase.net/reports/FBgn0036623.html protein_coding_gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity 0008152=metabolic process 0012505=endomembrane system AGPAT3 IPR002123=Phospholipid/glycerol acyltransferase CG4729 16-Dec-15 2015_12 "ENSDARG00000069044(agpat4),ENSDARG00000036549(LOC100334774)" "YDR018C(),YBR042C(CST26)" "WBGene00020264(acl-8),WBGene00044631(bus-18),WBGene00022646(acl-9)" "ENSXETG00000017998(agpat3),ENSXETG00000013131(agpat4)" "ENSMUSG00000001211(Agpat3),ENSMUSG00000023827(Agpat4)" "ENSG00000160216(AGPAT3),ENSG00000026652(AGPAT4)" "viable,fertile" FBgn0263479 scaRNA:ë¬U2-35.45 small Cajal body-specific RNA : ë¬U2-35.45 http://flybase.net/reports/FBgn0263479.html snoRNA_gene 0030565=snRNA pseudouridylation guide activity 0015030=Cajal body "pugU2-35/45, snoRNA:gp210-a" CR43594 16-Dec-15 2015_12 FBgn0004783 Ccp84Aa Ccp84Aa http://flybase.net/reports/FBgn0004783.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "unnamed, BG:DS00004.1, cc8, CG2360, Ccp, DmelCcp84Aa, cuticle cluster 8" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG2360 16-Dec-15 2015_12 viable DRSC12586 K 0.13265466 -0.464154429 0.190789573 0.374079829 1.653664281 -0.886318367 FBgn0004230 l(3)93Bd lethal (3) 93Bd http://flybase.net/reports/FBgn0004230.html gene "rlr2, l(3)rlr2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0013491 l(1)8PP9 lethal (1) 8PP9 http://flybase.net/reports/FBgn0013491.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" "embryo,germline clone,embryonic/first instar larval cuticle" FBgn0065947 l(2)SH0100 lethal (2) SH0100 http://flybase.net/reports/FBgn0065947.html gene l(2)SH2 0100 16-Dec-15 2015_12 "lethal,recessive" FBgn0034058 Pex11 Peroxin 11 http://flybase.net/reports/FBgn0034058.html protein_coding_gene "0007031=peroxisome organization, 0016559=peroxisome fission" "0005779=integral component of peroxisomal membrane, 0005777=peroxisome" "CG8315, DmelPex11, PEX11A, PEX11B" IPR008733=Peroxisomal biogenesis factor 11 CG8315 16-Dec-15 2015_12 "ENSDARG00000060707(si:dkeyp-84g1.1),ENSDARG00000069147(zgc:153402)" YOL147C(PEX11) "ENSXETG00000024160(PEX11B),ENSXETG00000017731(Q5BL92_XENTR)" "ENSMUSG00000074396,ENSMUSG00000030545(Pex11a)" "ENSG00000131779(PEX11B),ENSG00000166821(PEX11A)" "viable,fertile" FBgn0034103 CG15704 http://flybase.net/reports/FBgn0034103.html FBgn0062926 protein_coding_gene BcDNA:RH57845 CG15704 16-Dec-15 2015_12 FBgn0038596 CG14312 http://flybase.net/reports/FBgn0038596.html protein_coding_gene CG14312 16-Dec-15 2015_12 viable FBgn0259427 EP-149 http://flybase.net/reports/FBgn0259427.html gene 16-Dec-15 2015_12 visible wing FBgn0065266 l(2)SH2068 lethal (2) SH2068 http://flybase.net/reports/FBgn0065266.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034850 CG9875 http://flybase.net/reports/FBgn0034850.html FBgn0063226 protein_coding_gene 0030272=5-formyltetrahydrofolate cyclo-ligase activity BcDNA:GH23338 CG9875 16-Dec-15 2015_12 viable FBgn0005231 l(3)R18 lethal of Roberts 18 http://flybase.net/reports/FBgn0005231.html gene l(3)B18 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0035543 CG15020 http://flybase.net/reports/FBgn0035543.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle 0000902=cell morphogenesis 0016021=integral component of membrane IPR001507=Zona pellucida domain CG15020 16-Dec-15 2015_12 "WBGene00008978(cutl-3),WBGene00009041(cut-3),WBGene00000851(cut-1),WBGene00008482(cut-4),WBGene00011104(cut-5)" "viable,fertile" FBgn0265695 CR44502 http://flybase.net/reports/FBgn0265695.html non_protein_coding_gene CR44502 16-Dec-15 2015_12 FBgn0260743 GC1 Glutamate Carrier 1 http://flybase.net/reports/FBgn0260743.html "FBgn0037969, FBgn0015345" protein_coding_gene "0022857=transmembrane transporter activity, 0005314=high-affinity glutamate transmembrane transporter activity" "0055085=transmembrane transport, 0015813=L-glutamate transport, 0006839=mitochondrial transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "DmGC1, anon-87Ac, 87A7-9/4, CG18347" "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain, IPR002067=Mitochondrial carrier protein" CG18347 16-Dec-15 2015_12 "ENSDARG00000020718(LOC571044),ENSDARG00000058336,ENSDARG00000013749(zgc:92113),ENSDARG00000020893(slc25a22),ENSDARG00000070717(im:7143718)" WBGene00008979(F20D1.9) "ENSXETG00000000870(SLC25A18),ENSXETG00000023334(SLC25A22),ENSXETG00000015362(slc25a22)" "ENSMUSG00000019082(Slc25a22),ENSMUSG00000004902(Slc25a18)" "ENSG00000177542(SLC25A22),ENSG00000182902(SLC25A18)" FBgn0004944 agq atrophie gonadique http://flybase.net/reports/FBgn0004944.html gene 16-Dec-15 2015_12 "grandchildless,heat sensitive" "pole cell,heat sensitive,gonad" FBgn0062560 P42 P42 http://flybase.net/reports/FBgn0062560.html gene 16-Dec-15 2015_12 FBgn0262362 CG43060 http://flybase.net/reports/FBgn0262362.html protein_coding_gene CG43060 16-Dec-15 2015_12 FBgn0010770 ppan peter pan http://flybase.net/reports/FBgn0010770.html "FBgn0011392, FBgn0026381" protein_coding_gene "0048477=oogenesis, 0022008=neurogenesis, 0002164=larval development, 0007444=imaginal disc development" "peterpan, PPAN, Ppan, l(3)02231, Peter Pan, l(3)j6B6, CG5786" IPR007109=Brix domain CG5786 16-Dec-15 2015_12 ENSDARG00000022232(ppan) "YHR066W(SSF1),YDR312W(SSF2)" WBGene00003062(lpd-6) ENSXETG00000022055(ppan) ENSMUSG00000004100(Ppan) "ENSG00000221848,ENSG00000130810(PPAN)" " embryonic stage , adult stage && oogenesis stage "

ubiquitous "lethal,polyphasic,recessive,wild-type,visible,increased cell death,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,adult cuticle,wing margin bristle,egg,nurse cell,oocyte,wing,wing vein,posterior,wing disc,dorsal,wing hair & wing | dorsalBx-MS1096,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC17030 E 0.012365267 0.429085793 -2.129446907 -0.065422564 -0.421742788 -0.527329521 FBgn0035332 CG13801 http://flybase.net/reports/FBgn0035332.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane IPR004680=Citrate transporter-like domain CG13801 16-Dec-15 2015_12 FBgn0030850 stas Stasimon http://flybase.net/reports/FBgn0030850.html protein_coding_gene "0032224=positive regulation of synaptic transmission, cholinergic" "CG8408, Tmem41b, stymied in smn, stasimon" CG8408 16-Dec-15 2015_12 ENSDARG00000068092(LOC100333078) WBGene00006520(tag-175) ENSXETG00000024814(TMEM41B) ENSMUSG00000047554(Tmem41b) ENSG00000166471(TMEM41B) "viable,neurophysiology defective" "embryonic/larval neuromuscular junction | larval stage,embryonic/larval neuromuscular junction" FBgn0022221 l(2)k03303 lethal (2) k03303 http://flybase.net/reports/FBgn0022221.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260092 2L2769 http://flybase.net/reports/FBgn0260092.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0267582 CR45922 http://flybase.net/reports/FBgn0267582.html non_protein_coding_gene CR45922 16-Dec-15 2015_12 FBgn0037801 CG3999 http://flybase.net/reports/FBgn0037801.html protein_coding_gene 0004375=glycine dehydrogenase (decarboxylating) activity "0055114=oxidation-reduction process, 0006546=glycine catabolic process" 0005960=glycine cleavage complex "IPR020580=Glycine cleavage system P-protein, N-terminal, IPR020581=Glycine cleavage system P protein, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase, IPR003437=Glycine dehydrogenase (decarboxylating)" CG3999 16-Dec-15 2015_12 ENSDARG00000035120(gldc) YMR189W(GCV2) WBGene00020022(R12C12.1) ENSXETG00000000543(GLDC) ENSMUSG00000024827(Gldc) ENSG00000178445(GLDC) partially lethal - majority die FBgn0003439 smaller-eye smaller eye http://flybase.net/reports/FBgn0003439.html gene sme 16-Dec-15 2015_12 "male sterile,viable,male,reduced,visible,eye color defective" "pigment cell,eye,wing" FBgn0037426 CG18394 http://flybase.net/reports/FBgn0037426.html protein_coding_gene 16-Dec-15 2015_12 FBgn0026339 Su(tor)2-28-23 Su(tor)2-28-23 http://flybase.net/reports/FBgn0026339.html gene 16-Dec-15 2015_12 FBgn0020593 anon-57Cd anon-57Cd http://flybase.net/reports/FBgn0020593.html gene unnamed 16-Dec-15 2015_12 FBgn0050339 CG30339 http://flybase.net/reports/FBgn0050339.html FBgn0063671 protein_coding_gene 0005215=transporter activity 0006810=transport 0005622=intracellular BcDNA:RE54230 "IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR011074=CRAL/TRIO, N-terminal domain" CG30339 16-Dec-15 2015_12 FBgn0004747 l(3)85Fd lethal (3) 85Fd http://flybase.net/reports/FBgn0004747.html gene 16-Dec-15 2015_12 lethal FBgn0014105 anon-4Cd anon-4Cd http://flybase.net/reports/FBgn0014105.html gene "T8a,b, Transcript 8a,b" 16-Dec-15 2015_12 FBgn0001668 l(1)EN4 lethal (1) from Eugene Nonautonomous 4 http://flybase.net/reports/FBgn0001668.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0084170 Abd-B-PTS6 Abdominal B promoter targeting sequence 6 http://flybase.net/reports/FBgn0084170.html regulatory_region PTS-6 16-Dec-15 2015_12 FBgn0278603 Scr::Mmus\Hoxa5 http://flybase.net/reports/FBgn0278603.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0003404 Si Ski http://flybase.net/reports/FBgn0003404.html gene 16-Dec-15 2015_12 wild-type FBgn0021914 l(2)k11405 lethal (2) k11405 http://flybase.net/reports/FBgn0021914.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035704 CG10144 http://flybase.net/reports/FBgn0035704.html FBgn0062066 protein_coding_gene "0008270=zinc ion binding, 0051020=GTPase binding" "0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0016197=endosomal transport" 0033263=CORVET complex "Vps8, anon-WO0118547.365" "IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001841=Zinc finger, RING-type, IPR025941=Vacuolar protein sorting-associated protein 8, central domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000547=Clathrin, heavy chain/VPS, 7-fold repeat" CG10144 16-Dec-15 2015_12 ENSDARG00000060477(vps8) YAL002W(VPS8) WBGene00016582(C42C1.4) ENSXETG00000018613(VPS8) ENSMUSG00000033653(Vps8) ENSG00000156931(VPS8) viable FBgn0262018 CadN2 Cadherin-N2 http://flybase.net/reports/FBgn0262018.html "FBgn0262011, FBgn0032655" protein_coding_gene "0005509=calcium ion binding, 0004872=receptor activity, 0050839=cell adhesion molecule binding" "0045463=R8 cell development, 0016318=ommatidial rotation, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0044331=cell-cell adhesion mediated by cadherin, 0045467=R7 cell development, 0048846=axon extension involved in axon guidance" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "DN-cadh-like, cadN2, DmNCad2, CG7527, N-Cad2, Ncad2, CT23007, DN-like, CadN2, DN-Cad2, Cadherin N2r, N-cadherin2, DNcad2, NCad2, DN-cad2, DN-cadherin, CG42829" "IPR020894=Cadherin conserved site, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000233=Cadherin, cytoplasmic domain, IPR015919=Cadherin-like, IPR001881=EGF-like calcium-binding domain, IPR002126=Cadherin, IPR013032=EGF-like, conserved site, IPR027397=Catenin binding domain, IPR000742=EGF-like domain" CG42829 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" FBgn0065135 l(3)SH118 lethal (3) SH118 http://flybase.net/reports/FBgn0065135.html gene l(2)SH3 118 16-Dec-15 2015_12 "lethal,recessive" FBgn0065623 l(2)SH0799 lethal (2) SH0799 http://flybase.net/reports/FBgn0065623.html gene l(2)SH2 0799 16-Dec-15 2015_12 "lethal,recessive" FBgn0038961 CG13850 http://flybase.net/reports/FBgn0038961.html protein_coding_gene 0004672=protein kinase activity 0006468=protein phosphorylation GH07286p "IPR013584=RAP domain, IPR013579=FAST kinase-like protein, subdomain 2, IPR010622=FAST kinase leucine-rich" CG13850 16-Dec-15 2015_12 WBGene00007207(B0564.7) ENSXETG00000023866(BC075328.1) ENSMUSG00000000384(Tbrg4) ENSG00000136270(TBRG4) viable FBgn0022086 l(2)k07408 lethal (2) k07408 http://flybase.net/reports/FBgn0022086.html gene l(2)K07408 16-Dec-15 2015_12 "lethal,recessive" FBgn0265050 CR44165 http://flybase.net/reports/FBgn0265050.html non_protein_coding_gene CR44165 16-Dec-15 2015_12 FBgn0043474 micropia\pol pol http://flybase.net/reports/FBgn0043474.html transposable_element_gene 16-Dec-15 2015_12 FBgn0266959 CR45410 http://flybase.net/reports/FBgn0266959.html non_protein_coding_gene CR45410 16-Dec-15 2015_12 FBgn0033893 CG18371 http://flybase.net/reports/FBgn0033893.html protein_coding_gene 0003998=acylphosphatase activity "IPR017968=Acylphosphatase, conserved site, IPR001792=Acylphosphatase-like domain, IPR020456=Acylphosphatase" CG18371 16-Dec-15 2015_12 ENSXETG00000013250(acyp1) ENSG00000170634(ACYP2) viable FBgn0010025 E(Dl)F10 Enhancer of Delta F10 http://flybase.net/reports/FBgn0010025.html gene 16-Dec-15 2015_12 FBgn0022029 l(2)k01209 lethal (2) k01209 http://flybase.net/reports/FBgn0022029.html "FBgn0022251, FBgn0034213" protein_coding_gene "0004849=uridine kinase activity, 0005524=ATP binding" 0008655=pyrimidine-containing compound salvage "0005737=cytoplasm, 0005634=nucleus" "l(2)k08901, CG4798, l(2)K01209" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR029057=Phosphoribosyltransferase-like, IPR000764=Uridine kinase-like, IPR006083=Phosphoribulokinase/uridine kinase" CG4798 16-Dec-15 2015_12 "ENSDARG00000033916(si:ch211-243j20.2),ENSDARG00000001686(uckl1)" YNR012W(URK1) WBGene00008948(F19B6.1) ENSMUSG00000010492 ENSG00000198276(UCKL1) "lethal,recessive,viable,fertile" FBgn0263883 l(3)G34 http://flybase.net/reports/FBgn0263883.html gene 16-Dec-15 2015_12 "lethal,recessive,mitotic cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0053220 CG33220 http://flybase.net/reports/FBgn0053220.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024582 l(3)rO220 lethal (3) rO220 http://flybase.net/reports/FBgn0024582.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033828 CG17048 http://flybase.net/reports/FBgn0033828.html protein_coding_gene 0008270=zinc ion binding "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site" CG17048 16-Dec-15 2015_12 viable FBgn0262421 mir-13b-2 mir-13b-2 stem loop http://flybase.net/reports/FBgn0262421.html "FBgn0046828, FBgn0262265" miRNA_gene "miR-13b-2, mir-13b-2, CR42972, miR-13, dme-mir-13b, dme-miR-13b, mir-13b, dme-mir-13b-2, CR33079, miR-13B, 13b-1/2, Dme-miR-13b, miR-13b, miR-13-b2" CR42972 16-Dec-15 2015_12 embryonic stage -- adult stage viable FBgn0085337 CG34308 http://flybase.net/reports/FBgn0085337.html protein_coding_gene 0008270=zinc ion binding "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR018957=Zinc finger, C3HC4 RING-type" CG34308 16-Dec-15 2015_12 FBgn0250850 rig rigor mortis http://flybase.net/reports/FBgn0250850.html "FBgn0050149, FBgn0010589, FBgn0034531, FBgn0034533, FBgn0066866" protein_coding_gene "0005515=protein binding, 0030374=ligand-dependent nuclear receptor transcription coactivator activity" "0035075=response to ecdysone, 0008344=adult locomotory behavior, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0007629=flight behavior, 0007591=molting cycle, chitin-based cuticle" "0005634=nucleus, 0071254=cytoplasmic U snRNP body, 0005737=cytoplasm" "Rig, Gemin5, Rigor mortis, CG11171, CG30149, CG13440, l(2)05056, Gem5, anon-SAGE:Wang-132" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site" CG30149 16-Dec-15 2015_12 ENSXETG00000019404(GEMIN5) ENSMUSG00000037275(Gemin5) ENSG00000082516(GEMIN5) FBgn0259402 EP-501 http://flybase.net/reports/FBgn0259402.html gene 16-Dec-15 2015_12 visible wing vein FBgn0066359 l(2)199 lethal (2) 199 http://flybase.net/reports/FBgn0066359.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0047351 CG31468 http://flybase.net/reports/FBgn0047351.html "FBgn0045103, FBgn0045220, FBgn0045253, FBgn0045321, FBgn0051468" protein_coding_gene "NEST:bs18e02, NEST:bs21c04, NEST:bs34b06, NEST:bs12h04, Tes37, BcDNA:AT08725" IPR010736=Sperm-tail PG-rich repeat CG31468 16-Dec-15 2015_12 viable FBgn0041233 Gr59e Gustatory receptor 59e http://flybase.net/reports/FBgn0041233.html "FBgn0034874, FBgn0053151" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "gustatory receptor 59e, Gr59E, 59E.2, GR59E.2, CG15872, GR59e, 59E2, Gustatory receptor 59E.2, Gr59E2, CG33151" IPR013604=7TM chemoreceptor CG33151 16-Dec-15 2015_12 viable FBgn0022109 l(2)k07001 lethal (2) k07001 http://flybase.net/reports/FBgn0022109.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086296 bleb bleb http://flybase.net/reports/FBgn0086296.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0044061 GTD74-198 GTD74-198 http://flybase.net/reports/FBgn0044061.html gene 16-Dec-15 2015_12 viable FBgn0023054 l(1)3ABb lethal (1) 3ABb http://flybase.net/reports/FBgn0023054.html gene 1200C6 16-Dec-15 2015_12 "lethal,recessive" FBgn0266343 so::Optix http://flybase.net/reports/FBgn0266343.html engineered_fusion_gene 16-Dec-15 2015_12 "eye,ectopic" FBgn0267784 CR46115 http://flybase.net/reports/FBgn0267784.html non_protein_coding_gene CR46115 16-Dec-15 2015_12 FBgn0037275 CG14655 http://flybase.net/reports/FBgn0037275.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG14655 16-Dec-15 2015_12 "YPR015C(),YPR013C()" ENSMUSG00000022508(Bcl6) viable FBgn0040091 Ugt58Fa Ugt58Fa http://flybase.net/reports/FBgn0040091.html FBgn0034752 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG4414, AC 004377A, lectin-58Fg" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG4414 16-Dec-15 2015_12 "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" viable DRSC04470 K 0.182574293 0.710379522 0.472020452 0.037192778 0.4394413 -1.689647062 FBgn0025163 l(2)38Eb lethal (2) 38Eb http://flybase.net/reports/FBgn0025163.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031614 CG11934 http://flybase.net/reports/FBgn0031614.html protein_coding_gene 16-Dec-15 2015_12 FBgn0037851 CG4664 http://flybase.net/reports/FBgn0037851.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002003 l(2)36Bb lethal (2) 36Bb http://flybase.net/reports/FBgn0002003.html gene "l(2L)HT-7, l(2)HT-7" 16-Dec-15 2015_12 lethal FBgn0023162 Su(mg)1-6 Suppressor of modifier of gypsy 1-6 http://flybase.net/reports/FBgn0023162.html gene 16-Dec-15 2015_12 FBgn0065532 l(2)SH1106 lethal (2) SH1106 http://flybase.net/reports/FBgn0065532.html gene l(2)SH2 1106 16-Dec-15 2015_12 "lethal,recessive" FBgn0037137 Nopp140 Nopp140 http://flybase.net/reports/FBgn0037137.html "FBtr0089579, FBpp0088542, FBtr0089580, FBpp0089003" protein_coding_gene "0022008=neurogenesis, 0017126=nucleologenesis" 0005730=nucleolus "DmNopp140, CG7421, nopp140, Nopp- 140" "IPR007718=SRP40, C-terminal, IPR017859=Treacle-like, Treacher Collins Syndrome" CG7421 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0265988 mv mauve http://flybase.net/reports/FBgn0265988.html "FBgn0014363, FBgn0262110, FBgn0035296, FBgn0035297" protein_coding_gene "0007041=lysosomal transport, 0045771=negative regulation of autophagic vacuole size, 0007040=lysosome organization, 0006909=phagocytosis" "CG5691, CG42863, CG11814" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR000409=BEACH domain" CG42863 16-Dec-15 2015_12 "ENSDARG00000008575,ENSDARG00000021939" ENSMUSG00000019726(Lyst) ENSG00000143669(LYST) FBgn0250840 CG12907 http://flybase.net/reports/FBgn0250840.html "FBgn0033511, FBgn0044548, FBgn0061426, FBgn0066889" protein_coding_gene "anon-WO0140519.79, BcDNA:AT31822, anon-SAGE:Wang-109" CG12907 16-Dec-15 2015_12 FBgn0034497 CG9090 http://flybase.net/reports/FBgn0034497.html protein_coding_gene "0022857=transmembrane transporter activity, 0015114=phosphate ion transmembrane transporter activity" "0006817=phosphate ion transport, 0006839=mitochondrial transport" "0005740=mitochondrial envelope, 0031966=mitochondrial membrane" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG9090 16-Dec-15 2015_12 "ENSDARG00000025566(slc25a3),ENSDARG00000027424(slc25a3l)" YER053C(PIC2) "WBGene00008505(F01G4.6),WBGene00016358(C33F10.12),WBGene00011493(T05F1.8)" ENSXETG00000018767(SLC25A3) ENSMUSG00000061904(Slc25a3) ENSG00000075415(SLC25A3) viable FBgn0002016 l(2)36Fi lethal (2) 36Fi http://flybase.net/reports/FBgn0002016.html gene l(2)E105 16-Dec-15 2015_12 lethal FBgn0267028 CR45472 http://flybase.net/reports/FBgn0267028.html "FBgn0264331, FBgn0264332" non_protein_coding_gene "CR43790, CR43CR43790786, CR43791" CR45472 16-Dec-15 2015_12 FBgn0029728 CG2861 http://flybase.net/reports/FBgn0029728.html protein_coding_gene CG2861 16-Dec-15 2015_12 viable FBgn0259382 EP-329 http://flybase.net/reports/FBgn0259382.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0083995 CG41353 http://flybase.net/reports/FBgn0083995.html FBan0041353 protein_coding_gene 16-Dec-15 2015_12 FBgn0000109 Aprt Adenine phosphoribosyltransferase http://flybase.net/reports/FBgn0000109.html "FBgn0035288, FBgn0063099" protein_coding_gene 0003999=adenine phosphoribosyltransferase activity "0006168=adenine salvage, 0009116=nucleoside metabolic process, 0006166=purine ribonucleoside salvage" 0005737=cytoplasm "aprt, BcDNA:LP07986, Adenine Phosphoribosyltransferase, CG18315" "IPR029057=Phosphoribosyltransferase-like, IPR000836=Phosphoribosyltransferase domain, IPR005764=Adenine phosphoribosyl transferase" CG18315 16-Dec-15 2015_12 ENSDARG00000003519(aprt) "YML022W(APT1),YDR441C(APT2)" WBGene00020557(T19B4.3) ENSXETG00000027084(aprt) ENSMUSG00000006589(Aprt) ENSG00000198931(APRT) "chemical resistant,long lived,electrophoretic variant,fast,slow,viable" FBgn0032772 CG17350 http://flybase.net/reports/FBgn0032772.html protein_coding_gene CG17350 16-Dec-15 2015_12 "viable,fertile" FBgn0030305 CG1749 http://flybase.net/reports/FBgn0030305.html protein_coding_gene "0008265=Mo-molybdopterin cofactor sulfurase activity, 0071566=UFM1 activating enzyme activity" "0006777=Mo-molybdopterin cofactor biosynthetic process, 0071569=protein ufmylation" "0019008=molybdopterin synthase complex, 0005737=cytoplasm" "Uba5 homologue, dMoaD" "IPR000594=THIF-type NAD/FAD binding fold, IPR029752=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1, IPR016040=NAD(P)-binding domain" CG1749 16-Dec-15 2015_12 ENSDARG00000063588(uba5) WBGene00020184(T03F1.1) ENSXETG00000025266(ube1dc1) ENSMUSG00000032557(Uba5) ENSG00000081307(UBA5) "lethal,some die during pupal stage,viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259317 C17 http://flybase.net/reports/FBgn0259317.html gene 16-Dec-15 2015_12 visible wing vein FBgn0024900 anon-a5 anon-a5 http://flybase.net/reports/FBgn0024900.html repeat_region a5 16-Dec-15 2015_12 FBgn0001715 l(1)ESHS36 lethal (1) ESHS36 http://flybase.net/reports/FBgn0001715.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016126 CaMKI Calcium/calmodulin-dependent protein kinase I http://flybase.net/reports/FBgn0016126.html protein_coding_gene "0005516=calmodulin binding, 0004674=protein serine/threonine kinase activity, 0004683=calmodulin-dependent protein kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation 0005829=cytosol "Calcium/calmodulin-dependent protein kinase, CG1495, caMKI, calmodulin-dependent kinase, camKI, dCKI, CamKI" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR020636=Calcium/calmodulin-dependent/calcium-dependent protein kinase, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG1495 16-Dec-15 2015_12 "ENSDARG00000060116(LOC555945),ENSDARG00000029474(LOC794026),ENSDARG00000017446,ENSDARG00000008788(zgc:73155),ENSDARG00000044526(camk1g)" "YFR014C(CMK1),YOL016C(CMK2)" WBGene00000553(cmk-1) "ENSXETG00000023672(CAMK1),ENSXETG00000009110(CAMK1D),ENSXETG00000007699(PNCK),ENSXETG00000008939(CAMK1G)" "ENSMUSG00000039145(Camk1d),ENSMUSG00000030272(Camk1),ENSMUSG00000016179(Camk1g),ENSMUSG00000002012(Pnck)" "ENSG00000183049(CAMK1D),ENSG00000134072(CAMK1),ENSG00000008118(CAMK1G)" " adult stage , pupal stage&&larval stage&&adult stage " eye

"viable,fertile" FBgn0084036 CG41476 http://flybase.net/reports/FBgn0084036.html FBan0041476 protein_coding_gene 16-Dec-15 2015_12 FBgn0035420 CG14967 http://flybase.net/reports/FBgn0035420.html protein_coding_gene "IPR019441=FMP27, GFWDK domain, IPR019439=FMP27, N-terminal, IPR019409=FMP27, domain of unknown function DUF2405, IPR019443=FMP27, C-terminal" CG14967 16-Dec-15 2015_12 ENSDARG00000030945 "YLR454W(FMP27),YPR117W()" WBGene00009285(F31C3.3) ENSMUSG00000010277(2610507B11Rik) ENSG00000007202(KIAA0100) viable FBgn0053738 snmRNA:430:CR33738 snmRNA:430:CR33738 http://flybase.net/reports/FBgn0053738.html non_protein_coding_gene CR33738 CR33738 16-Dec-15 2015_12 FBgn0052272 tRNA:CR32272 transfer RNA:CR32272 http://flybase.net/reports/FBgn0052272.html "FBgn0011886, FBgn0011899, FBgn0060189" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K2:63B, transfer RNA:lys2:63B, tRNA:K:CTT:AE002584-b, tRNA[Lys][[2]], tRNA:K2, AE002584.trna20-LysCTT, CR32272, tRNA:lys2:63B, chr3L.trna48-LysCTT" CR32272 16-Dec-15 2015_12 FBgn0263834 CR43696 http://flybase.net/reports/FBgn0263834.html pseudogene_attribute CR43696 16-Dec-15 2015_12 FBgn0060841 l(3)S049413b lethal (3) S049413b http://flybase.net/reports/FBgn0060841.html gene 0494/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0036850 Gem2 Gemin2 http://flybase.net/reports/FBgn0036850.html protein_coding_gene "0007629=flight behavior, 0000245=spliceosomal complex assembly, 0008344=adult locomotory behavior, 0000387=spliceosomal snRNP assembly" "0005681=spliceosomal complex, 0071254=cytoplasmic U snRNP body" "CG10419, dGem2, dGemin2" "IPR007022=Gem-associated protein 2, IPR017364=Gem-associated protein 2, metazoa" CG10419 16-Dec-15 2015_12 ENSDARG00000015638(sip1) WBGene00004886(smi-1) ENSXETG00000000298(SIP1) ENSMUSG00000060121(Sip1) ENSG00000092208(GEMIN2) "lethal,heat sensitive,gravitaxis defective,progressive,flight defective,short lived,partially lethal - majority die,some die during pupal stage" FBgn0034638 CG10433 http://flybase.net/reports/FBgn0034638.html protein_coding_gene "0032504=multicellular organism reproduction, 0006952=defense response, 0045924=regulation of female receptivity" 0005615=extracellular space CG10433 16-Dec-15 2015_12 "lethal,viable" FBgn0025131 su(RpII140Z36)S16 su(RpII140Z36)S16 http://flybase.net/reports/FBgn0025131.html gene Z36[S16] 16-Dec-15 2015_12 FBgn0010307 mod(r)2 modulator of rudimentary 2 http://flybase.net/reports/FBgn0010307.html gene 16-Dec-15 2015_12 FBgn0262694 Su(VGlut)B14 http://flybase.net/reports/FBgn0262694.html gene B14 16-Dec-15 2015_12 FBgn0053056 CG33056 http://flybase.net/reports/FBgn0053056.html "FBgn0037058, FBgn0064118" protein_coding_gene CG10517 IPR002589=Macro domain CG33056 16-Dec-15 2015_12 "viable,visible" "trichogen cell,supernumerary" FBgn0044076 E(rst)I12 E(rst)I12 http://flybase.net/reports/FBgn0044076.html gene 0001745=compound eye morphogenesis I12 16-Dec-15 2015_12 viable FBgn0262881 CG43236 http://flybase.net/reports/FBgn0262881.html protein_coding_gene CG43236 16-Dec-15 2015_12 FBgn0060619 l(3)S088712b lethal (3) S088712b http://flybase.net/reports/FBgn0060619.html gene 0887/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0267268 CR45704 http://flybase.net/reports/FBgn0267268.html non_protein_coding_gene CR45704 16-Dec-15 2015_12 FBgn0060910 l(3)S042834a lethal (3) S042834a http://flybase.net/reports/FBgn0060910.html gene 0428/34 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002820 ms(2)10R male sterile (2) 10R http://flybase.net/reports/FBgn0002820.html gene 16-Dec-15 2015_12 "male sterile,recessive,female fertile" "spermatid axoneme,spermatid,spermatid & nucleus,Nebenkern derivative" FBgn0025772 l(3)89Ac lethal (3) 89Ac http://flybase.net/reports/FBgn0025772.html gene 16-Dec-15 2015_12 FBgn0054000 CG34000 http://flybase.net/reports/FBgn0054000.html FBgn0082839 protein_coding_gene "BP1067, unnamed" 16-Dec-15 2015_12 FBgn0033698 CG8858 http://flybase.net/reports/FBgn0033698.html protein_coding_gene "0000502=proteasome complex, 0005634=nucleus, 0005737=cytoplasm" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR024372=Proteasome stabiliser ECM29, IPR026827=Proteasome component ECM29/Translational activator GCN1" CG8858 16-Dec-15 2015_12 ENSDARG00000061952(LOC563777) YHL030W(ECM29) WBGene00008422(D2045.2) ENSMUSG00000050812(AI314180) ENSG00000136813(KIAA0368) viable FBgn0038235 CG8461 http://flybase.net/reports/FBgn0038235.html protein_coding_gene 0022008=neurogenesis IPR009292=Protein of unknown function DUF947 CG8461 16-Dec-15 2015_12 ENSDARG00000032516(si:dkey-236e20.6) WBGene00020705(T22H9.1) ENSMUSG00000023971(BC011248) ENSG00000124541(RRP36) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0003495 spz spatzle http://flybase.net/reports/FBgn0003495.html protein_coding_gene "0016015=morphogen activity, 0005125=cytokine activity, 0005121=Toll binding, 0042803=protein homodimerization activity, 0008083=growth factor activity" "0008592=regulation of Toll signaling pathway, 0009953=dorsal/ventral pattern formation, 0019732=antifungal humoral response, 0006952=defense response, 0008045=motor neuron axon guidance, 0050830=defense response to Gram-positive bacterium, 0000578=embryonic axis specification, 0006955=immune response, 0045087=innate immune response, 0009620=response to fungus, 0007310=oocyte dorsal/ventral axis specification, 0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway, 0006965=positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria, 0031334=positive regulation of protein complex assembly, 0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0006967=positive regulation of antifungal peptide biosynthetic process, 0050832=defense response to fungus" "0005576=extracellular region, 0043234=protein complex" "Spz, Protein spaetzle precursor, Spz1, CT19282, spazle, CG6134, spaztle, spaetzle, mel(3)7, Spaetzle, SPZ, Spatzle" IPR029034=Cystine-knot cytokine CG6134 16-Dec-15 2015_12 " oogenesis stage && adult stage | female , embryonic stage | 0-2 hr " ovary

"wild-type,immune response defective,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,dominant,partially lethal,neuroanatomy defective,locomotor rhythm defective,conditional,viable" "embryo,maternal effect,embryonic/first instar larval cuticle,ventral,dorsal,embryonic/larval somatic muscle,ventral furrow,supernumerary,ectopic,lateral,embryonic/larval fat body,embryonic/larval hemocoel" FBgn0003923 snRNA:U2:38ABb small nuclear RNA U2 at 38ABb http://flybase.net/reports/FBgn0003923.html FBgn0003919 snRNA_gene "0000398=mRNA splicing, via spliceosome" "0015030=Cajal body, 0005686=U2 snRNP" "snRNA-U2-141B, U2:38ABb, chr2L:19808533..19808709, K6, U2 snRNA, U2snRNA40AB, U2-38ABb, dU2, D.U2-4, snRNA[[1]], U2:39AB, CR32878, snRNA:U2:40AB, U2-141B, 38A U2, snRNA1, snRNA:U2, small nuclear RNA U2, U2, 141B, Dm U2-141B, snRNA2, U2 141B, U2snRNA" CR32878 16-Dec-15 2015_12 FBgn0038098 CG7381 http://flybase.net/reports/FBgn0038098.html protein_coding_gene CT22687 "IPR006149=EB domain, IPR000742=EGF-like domain" CG7381 16-Dec-15 2015_12 "WBGene00004114(pqn-25),WBGene00017032(D1044.7)" viable FBgn0038507 CG5863 http://flybase.net/reports/FBgn0038507.html protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis "IPR001969=Aspartic peptidase, active site, IPR001461=Aspartic peptidase, IPR021109=Aspartic peptidase domain" CG5863 16-Dec-15 2015_12 "ENSMUSG00000023987(Pgc),ENSMUSG00000004552(Ctse)" "viable,fertile" FBgn0050237 tRNA:CR30237 transfer RNA:CR30237 http://flybase.net/reports/FBgn0050237.html FBgn0060102 tRNA_gene 0033428=CAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna73-GlnCTG, tRNA:Q:CTG:AE002787, CR30237, AE002787.trna14-GlnCTG" CR30237 16-Dec-15 2015_12 FBgn0261535 l(2)34Fd lethal (2) 34Fd http://flybase.net/reports/FBgn0261535.html "FBgn0001969, FBgn0028529, FBgn0027888" protein_coding_gene 0005634=nucleus "CG7516, l(2)br15, lethal 15 in the black-reduced region, br15, BG:DS01068.6, A4, lethal group A4" "IPR012580=NUC153, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG7516 16-Dec-15 2015_12 ENSDARG00000020077(nol10) YGR145W(ENP2) WBGene00017989(nol-10) ENSXETG00000003518(NOL10) ENSMUSG00000061458(Nol10) ENSG00000115761(NOL10) FBgn0003683 term terminus http://flybase.net/reports/FBgn0003683.html FBgn0036792 protein_coding_gene "0003677=DNA binding, 0046872=metal ion binding" "Terminus, CG4216, Term, Bsg75C, ter" "IPR007087=Zinc finger, C2H2" CG4216 16-Dec-15 2015_12 FBgn0039833 CG15564 http://flybase.net/reports/FBgn0039833.html protein_coding_gene CG15564 16-Dec-15 2015_12 viable FBgn0261678 M(2)59B Minute (2) 59B http://flybase.net/reports/FBgn0261678.html gene RpL23 16-Dec-15 2015_12 FBgn0034132 S-Lap8 Sperm-Leucylaminopeptidase 8 http://flybase.net/reports/FBgn0034132.html FBgn0044589 protein_coding_gene "0030145=manganese ion binding, 0004177=aminopeptidase activity, 0008235=metalloexopeptidase activity" 0006508=proteolysis 0005737=cytoplasm "anon-WO0140519.41, Sperm-LeucylAminoPeptidase 8, S-LAP 8, CG4439" "IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356=Leucine aminopeptidase/peptidase B" CG4439 16-Dec-15 2015_12 viable DRSC21372 K 0.439770231 0.398592919 0.089189963 -0.980274059 0.904633889 1.558873231 FBgn0032120 CG33298 http://flybase.net/reports/FBgn0032120.html "FBgn0032121, FBgn0053298" protein_coding_gene "0000287=magnesium ion binding, 0005524=ATP binding, 0004012=phospholipid-translocating ATPase activity" "0007030=Golgi organization, 0034976=response to endoplasmic reticulum stress, 0045332=phospholipid translocation, 0006886=intracellular protein transport" 0016021=integral component of membrane "unnamed, DmCG33298, CG13112, CG18419" "IPR023299=P-type ATPase, cytoplasmic domain N, IPR006539=P-type ATPase, subfamily IV, IPR023214=HAD-like domain, IPR018303=P-type ATPase, phosphorylation site, IPR008250=P-type ATPase, A domain, IPR001757=P-type ATPase, IPR026871=Phospholipid-transporting P-type ATPase" CG33298 16-Dec-15 2015_12 "YDR093W(DNF2),YER166W(DNF1)" WBGene00012360(tat-3) ENSXETG00000024302(ATP10A) "ENSMUSG00000025324(Atp10a),ENSMUSG00000046808(Atp10d),ENSMUSG00000055415(Atp10b)" "ENSG00000145246(ATP10D),ENSG00000118322(ATP10B),ENSG00000206190(ATP10A)" viable DRSC02672 IK 1.613799992 0.10515359 -0.17819812 0.11138554 1.739709757 0.726226242 FBgn0265958 CR44745 http://flybase.net/reports/FBgn0265958.html non_protein_coding_gene CR44745 16-Dec-15 2015_12 FBgn0065253 l(2)SH2113 lethal (2) SH2113 http://flybase.net/reports/FBgn0065253.html gene l(2)SH2 2113 16-Dec-15 2015_12 "lethal,recessive" FBgn0020556 bxd bithoraxoid http://flybase.net/reports/FBgn0020556.html "FBgn0051273, FBgn0051277" non_protein_coding_gene "0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "CR31277, CR31273, bxd" CR31273 16-Dec-15 2015_12 FBgn0015880 anon-48Ai anon-48Ai http://flybase.net/reports/FBgn0015880.html gene "XI, transcript group XI" 16-Dec-15 2015_12 FBgn0005541 l(3)72Di lethal (3) 72Di http://flybase.net/reports/FBgn0005541.html gene 16-Dec-15 2015_12 lethal organism FBgn0259602 B0911 http://flybase.net/reports/FBgn0259602.html gene 16-Dec-15 2015_12 visible "wing vein L3,anterior crossvein,antennal segment,arista,tarsal segment,unguis" FBgn0023111 anon-10Aw anon-10Aw http://flybase.net/reports/FBgn0023111.html gene 16 16-Dec-15 2015_12 FBgn0267052 CR45496 http://flybase.net/reports/FBgn0267052.html pseudogene_attribute CR45496 16-Dec-15 2015_12 FBgn0053263 CG33263 http://flybase.net/reports/FBgn0053263.html FBgn0036358 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG14106 IPR002557=Chitin binding domain CG33263 16-Dec-15 2015_12 FBgn0262959 T:SS-Lcp2 Signal sequence of Lcp2 http://flybase.net/reports/FBgn0262959.html engineered_tag "T:Lcp2, Lcp2 signal sequence" 16-Dec-15 2015_12 FBgn0035035 CG3570 http://flybase.net/reports/FBgn0035035.html protein_coding_gene 0016433=rRNA (adenine) methyltransferase activity "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR021867=25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2" CG3570 16-Dec-15 2015_12 ENSDARG00000062181(zgc:153606) ENSXETG00000009257(Q5M798_XENTR) ENSMUSG00000042742(B630005N14Rik) ENSG00000164603(C7orf60) viable FBgn0267741 CR46072 http://flybase.net/reports/FBgn0267741.html pseudogene_attribute CR46072 16-Dec-15 2015_12 FBgn0000469 dlmd dorsal longitudinal muscle-defective http://flybase.net/reports/FBgn0000469.html gene 16-Dec-15 2015_12 "flight defective,dominant" FBgn0085737 CR40502 http://flybase.net/reports/FBgn0085737.html FBan0040502 rRNA_gene CR40502 16-Dec-15 2015_12 FBgn0082183 l(4)CB-6471-3 lethal (4) CB-6471-3 http://flybase.net/reports/FBgn0082183.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001413 l(1)3Ec lethal (1) 3Ec http://flybase.net/reports/FBgn0001413.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0039942 CG17163 http://flybase.net/reports/FBgn0039942.html FBan0017163 protein_coding_gene CG17163 16-Dec-15 2015_12 FBgn0011607 l(1)I33h29 lethal (1) I33h29 http://flybase.net/reports/FBgn0011607.html FBgn0010206 gene "l(1)I33b29, l(1)33h29" 16-Dec-15 2015_12 lethal FBgn0069338 UY2129 UY2129 http://flybase.net/reports/FBgn0069338.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0019968 Khc-73 Kinesin heavy chain 73 http://flybase.net/reports/FBgn0019968.html FBgn0025191 protein_coding_gene "0005524=ATP binding, 0042803=protein homodimerization activity, 0003777=microtubule motor activity, 0008017=microtubule binding" "0051294=establishment of spindle orientation, 0007018=microtubule-based movement, 0050803=regulation of synapse structure or activity" "0000235=astral microtubule, 0035371=microtubule plus-end, 0005769=early endosome, 0005871=kinesin complex" "CG8183, Kin73, KHC-73, DmKlp73, Kinesin-73, anon-EST:fe3C9, kinesin-73, Kinesin-3, KIF13A/B, KLP73, DmKIN73, kinesin heavy-chain 73, KIF 13A, DmKin73, unnamed, khc-73, anon-fast-evolving-3C9, Khc73" "IPR022140=Kinesin-like KIF1-type, IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR000253=Forkhead-associated (FHA) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000938=CAP Gly-rich domain, IPR008984=SMAD/FHA domain, IPR022164=Kinesin-like, IPR027640=Kinesin-like protein" CG8183 16-Dec-15 2015_12 ENSDARG00000002871 WBGene00002217(klp-4) ENSXETG00000000121(KIF13B) "ENSMUSG00000021375(Kif13a),ENSMUSG00000060012(Kif13b)" "ENSG00000137177(KIF13A),ENSG00000197892(KIF13B)" neurophysiology defective t-bar FBgn0266087 CR44829 http://flybase.net/reports/FBgn0266087.html non_protein_coding_gene CR44829 16-Dec-15 2015_12 FBgn0263210 CR43380 http://flybase.net/reports/FBgn0263210.html pseudogene_attribute CR43380 16-Dec-15 2015_12 FBgn0041118 l(2)k077 lethal (2) k077 http://flybase.net/reports/FBgn0041118.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0022291 l(2)04518b lethal (2) 04518b http://flybase.net/reports/FBgn0022291.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267428 CG45781 http://flybase.net/reports/FBgn0267428.html "FBgn0261404, FBan0040378, FBgn0058378, FBgn0263759" protein_coding_gene "40378, CG43676, CG42644, CG40378" "IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG45781 16-Dec-15 2015_12 "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" FBgn0011948 tRNA:R:12Ea transfer RNA:arg:12Ea http://flybase.net/reports/FBgn0011948.html "FBgn0011947, FBgn0052622, FBgn0060082" tRNA_gene "0033431=CGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[arg], tRNA:arg1, AE002593.trna4-ArgTCG, transfer RNA:arg1, tRNA:R1, tRNA:R:TCG:AE002593-b, CR32622, tRNA:arg12Ea, chrX.trna8-ArgTCG, tRNA-Arg" CR32622 16-Dec-15 2015_12 FBgn0085516 CG40769 http://flybase.net/reports/FBgn0085516.html FBan0040769 protein_coding_gene 16-Dec-15 2015_12 FBgn0039331 ND-49L NADH dehydrogenase (ubiquinone) 49 kDa subunit-like http://flybase.net/reports/FBgn0039331.html protein_coding_gene "0048038=quinone binding, 0003954=NADH dehydrogenase activity, 0051287=NAD binding, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH:ubiquinone oxidoreductase 49 kDa subunit, CG11913, CG111913, Q9VBR4_DROME, NUCM, NADH-ubiquinone oxidoreductase 49 kDa subunit" "IPR014029=NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site, IPR029014=NiFe hydrogenase-like, IPR022885=NAD(P)H-quinone oxidoreductase subunit D/H, IPR001135=NADH-quinone oxidoreductase, subunit D" CG11913 16-Dec-15 2015_12 viable FBgn0051680 CG31680 http://flybase.net/reports/FBgn0051680.html FBgn0047340 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space BcDNA:AT19802 CG31680 16-Dec-15 2015_12 viable FBgn0050485 CG30485 http://flybase.net/reports/FBgn0050485.html FBgn0033877 protein_coding_gene CG13342 CG30485 16-Dec-15 2015_12 viable FBgn0028645 beat-Ib beaten path Ib http://flybase.net/reports/FBgn0028645.html "FBgn0032576, FBgn0063001" protein_coding_gene "0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0007415=defasciculation of motor neuron axon, 0007155=cell adhesion, 0016198=axon choice point recognition" "0005887=integral component of plasma membrane, 0005576=extracellular region" "BG:DS00365.4, beat-B, BcDNA:RE51929, beat Ib, CG7644, CT23325, Beat-Ib" "IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG7644 16-Dec-15 2015_12 "viable,fertile" FBgn0010295 ng3 new glue 3 http://flybase.net/reports/FBgn0010295.html FBgn0063122 protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "ng, ng-3, EG:96G10.3, CG10788, BcDNA:LP03924" CG10788 16-Dec-15 2015_12 larval stage | third instar embryonic/larval salivary gland

viable FBgn0266136 Gyc76C Guanylyl cyclase at 76C http://flybase.net/reports/FBgn0266136.html "FBgn0261688, FBgn0250792, FBgn0013974, FBgn0052215, FBgn0026214, FBgn0084748, FBgn0260654, FBgn0261384, FBgn0261359, FBgn0084281" protein_coding_gene "0005524=ATP binding, 0004383=guanylate cyclase activity, 0004872=receptor activity, 0004672=protein kinase activity, 0001653=peptide receptor activity" "0007165=signal transduction, 0019934=cGMP-mediated signaling, 0007526=larval somatic muscle development, 0008045=motor neuron axon guidance, 0007428=primary branching, open tracheal system, 0009651=response to salt stress, 0006468=protein phosphorylation, 0007435=salivary gland morphogenesis, 0016199=axon midline choice point recognition, 0009190=cyclic nucleotide biosynthetic process" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "gimli, l(3)76BDl, DrGC-1, l(3)L0090, DGC1, unnamed, receptor-type guanylate cyclase, CG32215, GYC 76C, CG42636, lethal (3) L0090, drgc, gyc76C, CG8742, gim" "IPR001828=Receptor, ligand binding region, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR028082=Periplasmic binding protein-like I, IPR011009=Protein kinase-like domain, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG42636 16-Dec-15 2015_12 WBGene00001538(gcy-12) " embryonic stage -- adult stage , adult stage , embryonic stage | late , adult stage && oogenesis stage , embryonic stage | early " " adult midgut

, adult brain

, adult proventriculus

, embryonic/larval somatic muscle

, retina

, larval visceral muscle

, oocyte

, optic lobe

, pupal/adult digestive system

,

ubiquitous " FBgn0039798 CG11313 http://flybase.net/reports/FBgn0039798.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0042381=hemolymph coagulation" 0005576=extracellular region "c-SP11, SP11" "IPR001254=Serine proteases, trypsin domain, IPR006604=Disulphide knot CLIP, IPR001314=Peptidase S1A, chymotrypsin-type, IPR022700=Proteinase, regulatory CLIP domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG11313 16-Dec-15 2015_12 FBgn0032394 CG6746 http://flybase.net/reports/FBgn0032394.html protein_coding_gene 0019899=enzyme binding 0030497=fatty acid elongation 0005783=endoplasmic reticulum "IPR007482=Protein-tyrosine phosphatase-like, PTPLA" CG6746 16-Dec-15 2015_12 "ENSDARG00000014806(ptplb),ENSDARG00000022633(LOC553326)" YJL097W(PHS1) WBGene00020517(T15B7.2) "ENSXETG00000007988(PTPLB),ENSXETG00000007468(PTPLA)" "ENSMUSG00000035376(Ptplb),ENSMUSG00000063275(Ptpla)" "ENSG00000206527(PTPLB),ENSG00000165996(PTPLA)" lethal FBgn0033631 Sod3 Superoxide dismutase 3 http://flybase.net/reports/FBgn0033631.html "FBan0013200, FBgn0033630, FBtr0089938, FBpp0088877, FBtr0089939, FBpp0088878" protein_coding_gene "0004784=superoxide dismutase activity, 0005507=copper ion binding, 0008270=zinc ion binding" "0055114=oxidation-reduction process, 0009650=UV protection, 0019430=removal of superoxide radicals, 0006979=response to oxidative stress" "0005739=mitochondrion, 0005829=cytosol, 0005634=nucleus, 0005886=plasma membrane, 0005615=extracellular space" "SOD3, CG13200, CG9027, dSod3, CT25938, Dmel/CG9027" "IPR001424=Superoxide dismutase, copper/zinc binding domain, IPR018152=Superoxide dismutase, copper/zinc, binding site" CG9027 16-Dec-15 2015_12 "oxidative stress response defective,short lived,viable,body color defective" mesothoracic tergum FBgn0026678 l(1)G0104 lethal (1) G0104 http://flybase.net/reports/FBgn0026678.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0005420 l(1)adl9 lethal (1) adl9 http://flybase.net/reports/FBgn0005420.html gene l(1)adl-9 16-Dec-15 2015_12 "short lived,heat sensitive,partially lethal - majority die,lethal" FBgn0032061 CG9314 http://flybase.net/reports/FBgn0032061.html FBgn0044620 protein_coding_gene "0020037=heme binding, 0004096=catalase activity" "0055114=oxidation-reduction process, 0006979=response to oxidative stress" "Catalase B, anon-WO0140519.249, CT26521, CatB, kitty" "IPR002226=Catalase haem-binding site, IPR024711=Catalase, mono-functional, haem-containing, clades 1 and 3, IPR010582=Catalase immune-responsive domain, IPR011614=Catalase core domain, IPR018028=Catalase, mono-functional, haem-containing, IPR020835=Catalase-like domain" CG9314 16-Dec-15 2015_12 YDR256C(CTA1) "WBGene00000831(ctl-2),WBGene00000830(ctl-1),WBGene00013220(ctl-3)" "ENSXETG00000003981(BC090377.1),ENSXETG00000007561(TNeu041m16.1)" ENSMUSG00000027187(Cat) ENSG00000121691(CAT) "viable,visible" "adult heart,RU486 conditional,trichogen cell" FBgn0065175 l(3)SH016 lethal (3) SH016 http://flybase.net/reports/FBgn0065175.html gene l(2)SH3 016 16-Dec-15 2015_12 "lethal,recessive" FBgn0037500 CG17944 http://flybase.net/reports/FBgn0037500.html protein_coding_gene CG17944 16-Dec-15 2015_12 viable DRSC12572 I 0.753408372 -1.940362737 -0.196981762 0.253008363 0.212101108 0.234536605 FBgn0040509 ACXB ACXB http://flybase.net/reports/FBgn0040509.html "FBgn0004853, FBgn0032459" protein_coding_gene 0004016=adenylate cyclase activity "0009190=cyclic nucleotide biosynthetic process, 0035556=intracellular signal transduction, 0007283=spermatogenesis" 0016021=integral component of membrane "Ac34A, AC34A, DACXB, adenylyl cyclase, CG17174, AC, Adenylyl cyclase 34A" "IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG17174 16-Dec-15 2015_12 " pupal stage , larval stage | late , adult stage | male && spermatogenesis , adult stage | male " " spermatid | early

, spermatocyte

" viable FBgn0028128 l(3)S056113 lethal (3) S056113 http://flybase.net/reports/FBgn0028128.html gene 0561/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0051036 CG31036 http://flybase.net/reports/FBgn0051036.html "FBgn0039720, FBgn0039721" protein_coding_gene 0005929=cilium "CG15516, CG15518" CG31036 16-Dec-15 2015_12 viable FBgn0028977 v(2)k06408 v(2)k06408 http://flybase.net/reports/FBgn0028977.html gene 16-Dec-15 2015_12 "visible,recessive" FBgn0061066 l(3)S020202 lethal (3) S020202 http://flybase.net/reports/FBgn0061066.html gene 0202/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0035952 CG5280 http://flybase.net/reports/FBgn0035952.html protein_coding_gene IPR007914=Uncharacterised protein family UPF0193 CG5280 16-Dec-15 2015_12 ENSDARG00000052428(LOC795882) ENSXETG00000006345(C22orf23) ENSMUSG00000033029(1700088E04Rik) ENSG00000128346(C22orf23) viable FBgn0040215 fs(3)BQ16 fs(3)BQ16 http://flybase.net/reports/FBgn0040215.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0026562 SPARC "Secreted protein, acidic, cysteine-rich" http://flybase.net/reports/FBgn0026562.html FBgn0027691 protein_coding_gene 0005509=calcium ion binding "0007504=larval fat body development, 0030536=larval feeding behavior, 0007155=cell adhesion, 0070278=extracellular matrix constituent secretion, 0060438=trachea development, 0061327=anterior Malpighian tubule development, 0007498=mesoderm development, 0007165=signal transduction, 0070831=basement membrane assembly, 0007443=Malpighian tubule morphogenesis" "0005604=basement membrane, 0005578=proteinaceous extracellular matrix, 0005615=extracellular space" "dsparc, BM-40 Sparc, anon-EST:Posey291, CG6378, Sparc, Osteonectin, dSPARC, BM40, SPARC, BM-40/SPARC, BM-40-SPARC, sparc, CT19876" "IPR011992=EF-hand domain pair, IPR019577=SPARC/Testican, calcium-binding domain, IPR003645=Follistatin-like, N-terminal, IPR001999=Osteonectin-like, conserved site, IPR018247=EF-Hand 1, calcium-binding site" CG6378 16-Dec-15 2015_12 "ENSDARG00000019353(sparc),ENSDARG00000036591(sparcl1)" WBGene00003893(ost-1) ENSXETG00000010707(sparc) ENSMUSG00000029309(Sparcl1) ENSG00000152583(SPARCL1) "viable,lethal" "embryonic/first instar larval cuticle,presumptive embryonic/larval tracheal system,ventral nerve cord" FBgn0040764 CG13230 http://flybase.net/reports/FBgn0040764.html protein_coding_gene CG13230 16-Dec-15 2015_12 FBgn0034253 CG10936 http://flybase.net/reports/FBgn0034253.html protein_coding_gene IPR000082=SEA domain CG10936 16-Dec-15 2015_12 "viable,fertile" FBgn0011869 tRNA:G3:56EFa transfer RNA:gly3:56EFa http://flybase.net/reports/FBgn0011869.html "FBgn0003782, FBgn0050137, FBgn0050214, FBgn0060216" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30137, tRNA:gly3:56EFa, tRNA:G:GCC:AE002787-c, chr2R.trna42-GlyGCC, AE002787.trna58-GlyGCC, tRNA[Gly-GCC], CR30214" CR30214 16-Dec-15 2015_12 FBgn0262447 mir-14 mir-14 stem loop http://flybase.net/reports/FBgn0262447.html "FBgn0046827, FBgn0021957, FBgn0262306" miRNA_gene "0006402=mRNA catabolic process, 0042594=response to starvation, 0043066=negative regulation of apoptotic process, 0043069=negative regulation of programmed cell death, 0035071=salivary gland cell autophagic cell death, 0048190=wing disc dorsal/ventral pattern formation, 0019216=regulation of lipid metabolic process, 0048009=insulin-like growth factor receptor signaling pathway" "mir-34, mir-14, Mir-14, CR43013, miR14, CR33010, l(2)k10213, dme-miR-14, miR-14, dme-mir-14, mir14, 14" CR43013 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0001829 l(1)ts120 lethal (1) ts120 http://flybase.net/reports/FBgn0001829.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0267301 CR45737 http://flybase.net/reports/FBgn0267301.html non_protein_coding_gene CR45737 16-Dec-15 2015_12 FBgn0002685 mb minus bar http://flybase.net/reports/FBgn0002685.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0011078 l(1)Q33 lethal (1) Q33 http://flybase.net/reports/FBgn0011078.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0063261 CG31275 http://flybase.net/reports/FBgn0063261.html FBgn0051275 protein_coding_gene "0042623=ATPase activity, coupled" "0046331=lateral inhibition, 0007018=microtubule-based movement" "0005856=cytoskeleton, 0030286=dynein complex" "unnamed, CG14908, late transcript, BcDNA:GH08635" IPR016561=Dynein light chain roadblock-type 1/2 CG31275 16-Dec-15 2015_12 "viable,visible" chaeta FBgn0040536 CG12418 http://flybase.net/reports/FBgn0040536.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031568 CG10019 http://flybase.net/reports/FBgn0031568.html FBgn0043805 protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "BEST:GH25970, GH25970" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG10019 16-Dec-15 2015_12 viable FBgn0082631 S(CycEJP)2.7 S(CycEJP)2.7 http://flybase.net/reports/FBgn0082631.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264521 ff19 http://flybase.net/reports/FBgn0264521.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" spermatid FBgn0082975 snoRNA:ë¬28S-3305b snoRNA:ë¬28S-3305b http://flybase.net/reports/FBgn0082975.html snoRNA_gene "psi28s-3305b, CR34622" CR34622 16-Dec-15 2015_12 FBgn0033639 CG9003 http://flybase.net/reports/FBgn0033639.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0034976=response to endoplasmic reticulum stress, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "FBXL2, Fbxl5 iron sensing" "IPR026940=SCF E3 ubiquitin ligase complex F-box protein GrrA/Grr1, IPR006553=Leucine-rich repeat, cysteine-containing subtype, IPR001810=F-box domain" CG9003 16-Dec-15 2015_12 ENSDARG00000012135(fbxl2) YJR052W(RAD7) WBGene00015350(C02F5.7) ENSXETG00000023700(FBXL20) "ENSMUSG00000020883(Fbxl20),ENSMUSG00000032507(Fbxl2)" "ENSG00000108306(FBXL20),ENSG00000153558(FBXL2)" viable FBgn0259550 GG01430 http://flybase.net/reports/FBgn0259550.html gene 16-Dec-15 2015_12 visible "wing,anterior crossvein,tarsal segment,unguis,leg" FBgn0266183 CR44889 http://flybase.net/reports/FBgn0266183.html non_protein_coding_gene CR44889 16-Dec-15 2015_12 FBgn0032244 RfC3 Replication factor C subunit 3 http://flybase.net/reports/FBgn0032244.html protein_coding_gene "0005524=ATP binding, 0003677=DNA binding" "0022008=neurogenesis, 0006260=DNA replication, 0046331=lateral inhibition" "0005875=microtubule associated complex, 0005663=DNA replication factor C complex" "Rfc3, Drosophila replication factor C, RfC3, DRFC, CG5313, DmRFC3" "IPR013748=Replication factor C, C-terminal, IPR003593=AAA+ ATPase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR008921=DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal" CG5313 16-Dec-15 2015_12 ENSDARG00000035634(rfc5) YNL290W(RFC3) WBGene00018409(F44B9.8) ENSXETG00000022365(rfc5) ENSMUSG00000029363(Rfc5) ENSG00000111445(RFC5) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0032708 CG15166 http://flybase.net/reports/FBgn0032708.html protein_coding_gene 16-Dec-15 2015_12 FBgn0052205 CR32205 http://flybase.net/reports/FBgn0052205.html FBgn0064855 pseudogene_attribute "hp-CR32205, BcDNA:RE73739" CR32205 16-Dec-15 2015_12 FBgn0016931 smi45E smell impaired 45E http://flybase.net/reports/FBgn0016931.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0003258 rm rimy http://flybase.net/reports/FBgn0003258.html gene 16-Dec-15 2015_12 "viable,fertile,eye color defective,recessive,visible" "eye,wing" FBgn0022227 l(2)k03110 lethal (2) k03110 http://flybase.net/reports/FBgn0022227.html FBgn0022243 gene l(2)k02203 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0028269 l(1)G0437 lethal (1) G0437 http://flybase.net/reports/FBgn0028269.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0022333 f7 f7 http://flybase.net/reports/FBgn0022333.html gene 0007140=male meiosis 16-Dec-15 2015_12 "meiotic cell cycle defective,cytokinesis defective,male,recessive" "spermatocyte,primary spermatocyte cyst,onion stage spermatid,spermatozoon" FBgn0032115 CG4438 http://flybase.net/reports/FBgn0032115.html protein_coding_gene 0044822=poly(A) RNA binding "IPR019380=Casein kinase substrate, phosphoprotein PP28" CG4438 16-Dec-15 2015_12 "ENSDARG00000002967(pdap1),ENSDARG00000045153(slc16a8)" ENSXETG00000006062(PDAP1) ENSMUSG00000029623(Pdap1) ENSG00000106244(PDAP1) viable FBgn0039789 CG9717 http://flybase.net/reports/FBgn0039789.html protein_coding_gene 0015381=high-affinity sulfate transmembrane transporter activity "0008272=sulfate transport, 0055085=transmembrane transport" 0016021=integral component of membrane "IPR011547=SLC26A/SulP transporter domain, IPR001902=SLC26A/SulP transporter, IPR002645=STAS domain" CG9717 16-Dec-15 2015_12 "YLR092W(SUL2),YBR294W(SUL1)" ENSXETG00000019624(SLC26A11) viable FBgn0004748 l(3)89Ba lethal (3) 89Ba http://flybase.net/reports/FBgn0004748.html gene 16-Dec-15 2015_12 lethal FBgn0051353 CG31353 http://flybase.net/reports/FBgn0051353.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC23083 K 0.109900945 1.529388491 FBgn0051882 CG31882 http://flybase.net/reports/FBgn0051882.html FBgn0045094 protein_coding_gene "NEST:bs35a07, bs35a07.y1" CG31882 16-Dec-15 2015_12 viable FBgn0267537 CR45877 http://flybase.net/reports/FBgn0267537.html non_protein_coding_gene CR45877 16-Dec-15 2015_12 FBgn0051337 CG31337 http://flybase.net/reports/FBgn0051337.html FBgn0063678 protein_coding_gene BcDNA:RE40816 "IPR022700=Proteinase, regulatory CLIP domain" CG31337 16-Dec-15 2015_12 viable FBgn0069226 gl(2L)50-27 gl(2L)50-27 http://flybase.net/reports/FBgn0069226.html gene 0009952=anterior/posterior pattern specification 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0031233 Tbc1d15-17 "TBC1 domain family, member 15/17 ortholog (H. sapiens)" http://flybase.net/reports/FBgn0031233.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity CG11490 IPR000195=Rab-GTPase-TBC domain CG11490 16-Dec-15 2015_12 "ENSDARG00000005927(tbc1d17),ENSDARG00000057218(tbc1d15)" ENSXETG00000022908(TBC1D14) "viable,fertile" FBgn0027603 Ulp1 Ulp1 http://flybase.net/reports/FBgn0027603.html protein_coding_gene "0005515=protein binding, 0016929=SUMO-specific protease activity" "0035204=negative regulation of lamellocyte differentiation, 0016926=protein desumoylation, 0050728=negative regulation of inflammatory response, 0045751=negative regulation of Toll signaling pathway, 0071456=cellular response to hypoxia, 0060997=dendritic spine morphogenesis, 0021952=central nervous system projection neuron axonogenesis" "0005637=nuclear inner membrane, 0005643=nuclear pore, 0005634=nucleus, 0005737=cytoplasm" "ulp1, CG12359, DmUlp1, BcDNA:GH02751, ubiquitin-like protein-specific protease 1" "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG12359 16-Dec-15 2015_12 WBGene00006736(ulp-1) "viable,fertile,male sterile,lethal,recessive,partially lethal - majority die,visible" "denticle belt,mesothoracic tergum" FBgn0003063 anon-Pen68A anon-Pen68A http://flybase.net/reports/FBgn0003063.html gene "Pen68A, GCR16, GCR-16, pen68A" 16-Dec-15 2015_12 FBgn0039157 Myo95E Myosin 95E http://flybase.net/reports/FBgn0039157.html "FBgn0051134, FBgn0051135" protein_coding_gene "0005524=ATP binding, 0003774=motor activity, 0042623=ATPase activity, coupled" 0016459=myosin complex "myo 95E, CG31134, CG31135, 95E, CG5501, DmAE003746, Dm95E" "IPR000048=IQ motif, EF-hand binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001609=Myosin head, motor domain, IPR010926=Unconventional myosin tail, actin- and lipid-binding" CG5501 16-Dec-15 2015_12 viable male genitalia FBgn0033710 CG17739 http://flybase.net/reports/FBgn0033710.html FBgn0045919 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005576=extracellular region "CT39321, Fat-spondin, anon-WO0153538.35" "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR009465=Spondin, N-terminal, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR002861=Reeler domain" CG17739 16-Dec-15 2015_12 "ENSDARG00000023694(spon1b),ENSDARG00000010029(spon1a)" ENSXETG00000009063(SPON1) ENSMUSG00000038156(Spon1) ENSG00000152268(SPON1) viable FBgn0262858 CG43222 http://flybase.net/reports/FBgn0262858.html protein_coding_gene DMG4-MB6.chr3R.35.021 CG43222 16-Dec-15 2015_12 FBgn0064162 lin-10 lin-10 http://flybase.net/reports/FBgn0064162.html gene Flin-10 16-Dec-15 2015_12 FBgn0054034 CG34034 http://flybase.net/reports/FBgn0054034.html FBgn0082652 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "unnamed, BP1088, HDC14863" CG34034 16-Dec-15 2015_12 FBgn0032478 CG5458 http://flybase.net/reports/FBgn0032478.html protein_coding_gene IPR003409=MORN motif CG5458 16-Dec-15 2015_12 ENSDARG00000070446(LOC100334583) ENSMUSG00000024033(Rsph1) ENSG00000160188(RSPH1) viable FBgn0013455 fs(2)neo12 fs(2)neo12 http://flybase.net/reports/FBgn0013455.html gene unnamed 16-Dec-15 2015_12 "female sterile,lethal,maternal effect" FBgn0003560 Su(f)D "Suppressor of forked, Dominant" http://flybase.net/reports/FBgn0003560.html gene "Suppressor of forked of Dobzhansky, Su(f), Suppressor of forked, Su[D]-f" 16-Dec-15 2015_12 "lethal,recessive,female semi-sterile" macrochaeta FBgn0039480 Cpr97Ea Cuticular protein 97Ea http://flybase.net/reports/FBgn0039480.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG6131 IPR000618=Insect cuticle protein CG6131 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262943 CR43262 http://flybase.net/reports/FBgn0262943.html non_protein_coding_gene CR43262 16-Dec-15 2015_12 FBgn0027790 GV1 GV1 http://flybase.net/reports/FBgn0027790.html "FBgn0035278, FBgn0061378" protein_coding_gene 0003677=DNA binding "0005634=nucleus, 0031965=nuclear membrane" "CG12023, BcDNA:RH49123, DIP1" CG12023 16-Dec-15 2015_12 embryonic stage -- adult stage organism

embryonic stage organism

viable FBgn0266149 CR44855 http://flybase.net/reports/FBgn0266149.html non_protein_coding_gene CR44855 16-Dec-15 2015_12 FBgn0060413 l(3)S129803 lethal (3) S129803 http://flybase.net/reports/FBgn0060413.html gene 1298/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0264302 CG43780 http://flybase.net/reports/FBgn0264302.html FBgn0035765 protein_coding_gene CG8600 CG43780 16-Dec-15 2015_12 "viable,fertile" FBgn0036949 CG7290 http://flybase.net/reports/FBgn0036949.html protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG7290 16-Dec-15 2015_12 viable FBgn0013632 l(3)neo51 lethal (3) neo51 http://flybase.net/reports/FBgn0013632.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0031677 CG14036 http://flybase.net/reports/FBgn0031677.html protein_coding_gene 0055070=copper ion homeostasis "IPR022776=TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG14036 16-Dec-15 2015_12 ENSG00000124196(GTSF1L) viable FBgn0065864 l(2)SH0267 lethal (2) SH0267 http://flybase.net/reports/FBgn0065864.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003473 sph sparse hairs http://flybase.net/reports/FBgn0003473.html gene "0008587=imaginal disc-derived wing margin morphogenesis, 0001745=compound eye morphogenesis" "section 26, l(1)x-4, 26, x-4, section 30, 4P1, R-9-5, l(1)R-9-5, l(1)20Ea, l(1)X-4, l4P1, section 27, X-4, l(1)S1, lX4, 27, 30, 18, l(1)sph, l(1)7-96, section 18" 16-Dec-15 2015_12 "visible,recessive,heat sensitive,lethal,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "adult thorax & microchaeta,eye,wing,adult thorax & microchaeta | conditional ts,heat sensitive,ovariole,germline clone,egg" FBgn0002103 l(2)57Dd lethal (2) 57Dd http://flybase.net/reports/FBgn0002103.html gene 16-Dec-15 2015_12 lethal FBgn0032805 CG10337 http://flybase.net/reports/FBgn0032805.html protein_coding_gene 0016021=integral component of membrane "IPR004877=Cytochrome b561 domain, IPR006593=Cytochrome b561/ferric reductase transmembrane" CG10337 16-Dec-15 2015_12 viable FBgn0027930 MP1 Melanization Protease 1 http://flybase.net/reports/FBgn0027930.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" "0006952=defense response, 0009620=response to fungus, 0006508=proteolysis, 0035006=melanization defense response" "SP25, proPO-AE, BEST:GH02921, melanization protease 1, CG1102" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR006604=Disulphide knot CLIP, IPR001314=Peptidase S1A, chymotrypsin-type, IPR022700=Proteinase, regulatory CLIP domain" CG1102 16-Dec-15 2015_12 "developmental rate defective,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal,wound healing defective,viable" "melanotic mass | larval stage,melanotic mass | P-stage,melanotic mass | adult stage" FBgn0083022 snoRNA:ë¬18S-640e snoRNA:ë¬18S-640e http://flybase.net/reports/FBgn0083022.html snoRNA_gene "psi18s-640e, CR34581" CR34581 16-Dec-15 2015_12 FBgn0028952 Kebab Kinetochore and EB1 associated basic protein http://flybase.net/reports/FBgn0028952.html FBgn0051672 protein_coding_gene "0043515=kinetochore binding, 0008017=microtubule binding" "0000777=condensed chromosome kinetochore, 0048471=perinuclear region of cytoplasm, 0005876=spindle microtubule" "n(2)k09932, kebab, kinetochore and EB1 associated basic protein, BEST:LD15963, CG31672, CG4248, keb" CG31672 16-Dec-15 2015_12 "viable,fertile" FBgn0259863 Su(Ste):CR42432 Su(Ste):CR42432 http://flybase.net/reports/FBgn0259863.html non_protein_coding_gene CR42432 CR42432 16-Dec-15 2015_12 FBgn0051659 CG31659 http://flybase.net/reports/FBgn0051659.html FBgn0031336 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG16933 "IPR022271=Lipocalin, ApoD type, IPR012674=Calycin, IPR011038=Calycin-like" CG31659 16-Dec-15 2015_12 viable FBgn0003626 Su(var)314 Suppressor of variegation 314 http://flybase.net/reports/FBgn0003626.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable" FBgn0028637 ifm(2)RU5 indirect flight muscle (2) RU5 http://flybase.net/reports/FBgn0028637.html gene 0007517=muscle organ development 0005703=polytene chromosome puff 16-Dec-15 2015_12 "visible,recessive,flight defective,sterile,viable" "indirect flight muscle,indirect flight muscle & myofibril,wing,dorsal medial muscle" FBgn0011133 l(1)Q208 lethal (1) Q208 http://flybase.net/reports/FBgn0011133.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0265198 CR44258 http://flybase.net/reports/FBgn0265198.html non_protein_coding_gene CR44258 16-Dec-15 2015_12 FBgn0013656 ms(2)neo1 male sterile (2) neo1 http://flybase.net/reports/FBgn0013656.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0264716 CR43984 http://flybase.net/reports/FBgn0264716.html non_protein_coding_gene CR43984 16-Dec-15 2015_12 FBgn0065153 l(3)SH064 lethal (3) SH064 http://flybase.net/reports/FBgn0065153.html gene l(2)SH3 064 16-Dec-15 2015_12 "lethal,recessive" FBgn0000983 fs(2)HO308 female sterile (2) HO308 http://flybase.net/reports/FBgn0000983.html gene fs(2)308A 16-Dec-15 2015_12 FBgn0005416 l(1)adl5 lethal (1) adl5 http://flybase.net/reports/FBgn0005416.html gene l(1)adl-5 16-Dec-15 2015_12 "lethal,heat sensitive,short lived" FBgn0039051 CG17109 http://flybase.net/reports/FBgn0039051.html protein_coding_gene 0004046=aminoacylase activity 0006520=cellular amino acid metabolic process 0005737=cytoplasm "IPR002933=Peptidase M20, IPR011650=Peptidase M20, dimerisation domain, IPR010159=N-acyl-L-amino-acid amidohydrolase" CG17109 16-Dec-15 2015_12 "ENSDARG00000004845(LOC100001620),ENSDARG00000038475(zgc:55605)" "WBGene00007507(C10C5.3),WBGene00007508(C10C5.4),WBGene00007509(C10C5.5),WBGene00015509(C06A6.4)" ENSXETG00000000089(acy1) ENSMUSG00000023262(Acy1) ENSG00000114786(ACY1) "partially lethal - majority die,some die during pupal stage,viable" FBgn0031054 Ssu72 Ssu72 CTD phosphatase http://flybase.net/reports/FBgn0031054.html FBgn0029511 protein_coding_gene "0016791=phosphatase activity, 0008420=CTD phosphatase activity" "0031124=mRNA 3'-end processing, 0070940=dephosphorylation of RNA polymerase II C-terminal domain" 0005634=nucleus "CG14216, Ssu72 ortholog, BEST:CK01830, Ssu72, dSsu72" IPR006811=RNA polymerase II subunit A CG14216 16-Dec-15 2015_12 YNL222W(SSU72) WBGene00020480(ssup-72) ENSXETG00000012963() ENSMUSG00000029038(Ssu72) "ENSG00000160075(SSU72),ENSG00000186232,ENSG00000186223" "viable,visible,lethal,recessive" trichogen cell FBgn0001709 l(1)ESHS30 lethal (1) ESHS30 http://flybase.net/reports/FBgn0001709.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086168 E(var)2-1 Enhancer of variegation 2-1 http://flybase.net/reports/FBgn0086168.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0083036 snoRNA:ë¬18S-525c snoRNA:ë¬18S-525c http://flybase.net/reports/FBgn0083036.html snoRNA_gene "psi18S-525c, CR34573" CR34573 16-Dec-15 2015_12 FBgn0038602 CG7126 http://flybase.net/reports/FBgn0038602.html protein_coding_gene CG7126 16-Dec-15 2015_12 viable FBgn0277428 l(3)psg29 http://flybase.net/reports/FBgn0277428.html gene psg29 16-Dec-15 2015_12 FBgn0030242 sofe sister of feo http://flybase.net/reports/FBgn0030242.html protein_coding_gene "0004871=signal transducer activity, 0008017=microtubule binding" "0007186=G-protein coupled receptor signaling pathway, 0000226=microtubule cytoskeleton organization, 0000910=cytokinesis" 0005834=heterotrimeric G-protein complex CG1655 "IPR015898=G-protein gamma-like domain, IPR007145=Microtubule-associated protein, MAP65/Ase1/PRC1" CG1655 16-Dec-15 2015_12 "ENSDARG00000005993(prc1b),ENSDARG00000010511(prc1a),ENSDARG00000005098(zgc:86764)" YOR058C(ASE1) "ENSXETG00000015449(PRC1),ENSXETG00000018081()" ENSMUSG00000038943(Prc1) ENSG00000198901(PRC1) "viable,fertile" FBgn0262631 CR43148 http://flybase.net/reports/FBgn0262631.html non_protein_coding_gene CR43148 16-Dec-15 2015_12 FBgn0050122 CG30122 http://flybase.net/reports/FBgn0050122.html "FBgn0034369, FBgn0034370" protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome "SAF-A, LD11002, CG5477, CG18610" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003877=SPRY domain, IPR003034=SAP domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001870=B30.2/SPRY domain" CG30122 16-Dec-15 2015_12 "ENSDARG00000040564(hnrnpul1),ENSDARG00000004735(hnrnpu),ENSDARG00000015206(wu:fc51c09)" WBGene00012769(Y41E3.11) "ENSXETG00000018718(HNRNPUL1),ENSXETG00000011386(hnrpu)" "ENSMUSG00000040725(Hnrnpul1),ENSMUSG00000039630(Hnrnpu),ENSMUSG00000071659(Hnrnpul2)" "ENSG00000105323(HNRNPUL1),ENSG00000153187(HNRNPU),ENSG00000214753(HNRNPUL2)" viable FBgn0065908 l(2)SH0185 lethal (2) SH0185 http://flybase.net/reports/FBgn0065908.html gene l(2)SH2 0185 16-Dec-15 2015_12 "lethal,recessive" FBgn0039670 CG7567 http://flybase.net/reports/FBgn0039670.html FBgn0063003 protein_coding_gene BcDNA:RE47447 IPR007931=Protein of unknown function DUF725 CG7567 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0020445 E23 Early gene at 23 http://flybase.net/reports/FBgn0020445.html "FBgn0031524, FBgn0031525" protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0042752=regulation of circadian rhythm "0016020=membrane, 0043190=ATP-binding cassette (ABC) transporter complex" "CG15410, CG3327" "IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3327 16-Dec-15 2015_12 "viable,locomotor rhythm defective,lethal,circadian rhythm defective" FBgn0021974 l(2)k09932 lethal (2) k09932 http://flybase.net/reports/FBgn0021974.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003159 CG2841 http://flybase.net/reports/FBgn0003159.html FBgn0029614 protein_coding_gene "proximal to raf, CG2841, EG:BACH48C10.5, ptr" CG2841 16-Dec-15 2015_12 viable FBgn0259741 CG42395 http://flybase.net/reports/FBgn0259741.html protein_coding_gene IPR006696=Protein of unknown function DUF423 CG42395 16-Dec-15 2015_12 WBGene00013720(Y106G6H.8) ENSMUSG00000070394(1810027O10Rik) ENSG00000205544(C17orf61) FBgn0027315 l(1)G0090 lethal (1) G0090 http://flybase.net/reports/FBgn0027315.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002161 l(2)Sp2b lethal (2) Sp2b http://flybase.net/reports/FBgn0002161.html gene 16-Dec-15 2015_12 lethal FBgn0001991 Ca-ë±1D Ca2+-channel protein ë±1 subunit D http://flybase.net/reports/FBgn0001991.html FBgn0004881 protein_coding_gene 0005245=voltage-gated calcium channel activity "0006936=muscle contraction, 0042045=epithelial fluid transport, 0006816=calcium ion transport, 0070588=calcium ion transmembrane transport" "0005891=voltage-gated calcium channel complex, 0016323=basolateral plasma membrane, 0016324=apical plasma membrane" "Caalpha1D, Ca-_1D, l(2)35Fa, DmCa1D, Drosophila melanogaster calcium channel alpha[[1]] subunit DHP-sensitive, BG:DS02795.1, CG4894, Ca2+-channel protein alpha1 subunit D, Ca[2+]-channel alpha1 subunit, cad, ca-alpha1D, l35Fa, calcium channel alpha-1 subunit, alpha1D, Ca-a1D, DroCa1, alpha1, Ca-alpha[[1]]D, Ca-alpha1D, DmCa1alpha1, Ca-alpha1, Dmca1D, ca-alpha1d, Ca_alpha1D" "IPR005821=Ion transport domain, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR014873=Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, IPR005446=Voltage-dependent calcium channel, L-type, alpha-1 subunit, IPR002077=Voltage-dependent calcium channel, alpha-1 subunit" CG4894 16-Dec-15 2015_12 "ENSDARG00000008398(cacna1c),ENSDARG00000024004(cacna1d),ENSDARG00000023683(cacna1f),ENSDARG00000042552(cacna1sb)" YGR217W(CCH1) WBGene00001187(egl-19) ENSXETG00000007195(CACNA1F) "ENSMUSG00000015968(Cacna1d),ENSMUSG00000051331(Cacna1c),ENSMUSG00000031142(Cacna1f),ENSMUSG00000026407(Cacna1s)" "ENSG00000157388(CACNA1D),ENSG00000151067(CACNA1C),ENSG00000102001(CACNA1F),ENSG00000081248(CACNA1S)" " adult stage , pupal stage | late , embryonic stage | 9-12 hr , embryonic stage " " adult head

, embryonic nervous system

" "lethal,recessive,wild-type,neuroanatomy defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,longitudinal connective,abdominal segmental nerve,NMJ bouton,neuromuscular junction,embryonic/larval tracheal system,embryonic/larval midgut,cephalopharyngeal skeleton,embryonic/larval dorsal vessel" FBgn0265380 CR44321 http://flybase.net/reports/FBgn0265380.html non_protein_coding_gene CR44321 16-Dec-15 2015_12 FBgn0036851 CG14082 http://flybase.net/reports/FBgn0036851.html protein_coding_gene CG14082 16-Dec-15 2015_12 viable FBgn0011320 l(3)j2A2 lethal (3) j2A2 http://flybase.net/reports/FBgn0011320.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260623 2L3328 http://flybase.net/reports/FBgn0260623.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0261526 NT1 Neurotrophin 1 http://flybase.net/reports/FBgn0261526.html "FBgn0084557, FBgn0260984, FBgn0087009, FBgn0260813, FBgn0052242, FBgn0035556, FBgn0052244" protein_coding_gene "0005121=Toll binding, 0008083=growth factor activity" "0008045=motor neuron axon guidance, 0031637=regulation of neuronal synaptic plasticity in response to neurotrophin, 0043523=regulation of neuron apoptotic process, 0008063=Toll signaling pathway, 0007411=axon guidance, 0021556=central nervous system formation, 0007399=nervous system development, 0010941=regulation of cell death" 0005576=extracellular region "Drosophila Neurotrophin1, CT30097, spatzle 2, CG42576, dNT1, DNT1, Spz2, Spatzle 2, CG32242, CG18318, spz2, CG32244" IPR029034=Cystine-knot cytokine CG42576 16-Dec-15 2015_12 FBgn0028620 l(2)10565a lethal (2) 10565a http://flybase.net/reports/FBgn0028620.html gene l(2)10565 16-Dec-15 2015_12 "lethal,recessive" FBgn0262516 Trpml "Transient receptor potential cation channel, mucolipin ortholog" http://flybase.net/reports/FBgn0262516.html "FBgn0036904, FBgn0084940" protein_coding_gene "0005261=cation channel activity, 0005217=intracellular ligand-gated ion channel activity, 0080025=phosphatidylinositol-3,5-bisphosphate binding, 0005262=calcium channel activity" "0006812=cation transport, 0046331=lateral inhibition, 0044130=negative regulation of growth of symbiont in host, 0006816=calcium ion transport, 0006914=autophagy, 0000046=autophagic vacuole fusion, 0032008=positive regulation of TOR signaling, 0006874=cellular calcium ion homeostasis" "0005886=plasma membrane, 0036020=endolysosome membrane, 0034703=cation channel complex, 0005765=lysosomal membrane, 0031902=late endosome membrane, 0005764=lysosome" "Transient Receptor Potential mucolipin, DmTRPML, CT25240, transient receptor potential mucolipin, CG8743, trpml, TRPML, l(3)76BDi, TRP Mucolipin" "IPR013122=Polycystin cation channel, PKD1/PKD2" CG8743 16-Dec-15 2015_12 "ENSDARG00000018722,ENSDARG00000002285" WBGene00000846(cup-5) "ENSXETG00000008633(mcoln3),ENSXETG00000006812(mcoln1)" "ENSMUSG00000036853(Mcoln3),ENSMUSG00000011008(Mcoln2),ENSMUSG00000004567(Mcoln1)" "ENSG00000055732(MCOLN3),ENSG00000153898(MCOLN2),ENSG00000090674(MCOLN1)" DRSC11032 I -1.633237991 -0.323258828 0.189626555 -0.17759202 0.022775855 -0.333471541 FBgn0044345 scratch-like2 scratch-like2 http://flybase.net/reports/FBgn0044345.html gene 16-Dec-15 2015_12 FBgn0051528 CG31528 http://flybase.net/reports/FBgn0051528.html "FBan0031528, FBgn0045807, FBgn0047301" protein_coding_gene "BEST:GH26112, BcDNA:GH26112" "IPR015940=Ubiquitin-associated domain, IPR000626=Ubiquitin domain, IPR009060=UBA-like, IPR015496=Ubiquilin, IPR029071=Ubiquitin-related domain" CG31528 16-Dec-15 2015_12 viable FBgn0267728 otk2 off-track2 http://flybase.net/reports/FBgn0267728.html "FBgn0033674, FBgn0065384" protein_coding_gene "0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0017147=Wnt-protein binding" "0048803=imaginal disc-derived male genitalia morphogenesis, 0035260=internal genitalia morphogenesis, 0048804=imaginal disc-derived female genitalia morphogenesis" 0016021=integral component of membrane "Off-track2, l(2)SH2 1639, l(2)SH1639, lethal (2) SH1639, CT25760, CG8964" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG8964 16-Dec-15 2015_12 ENSDARG00000070384 "ENSXETG00000019135(),ENSXETG00000015506(),ENSXETG00000015524(),ENSXETG00000015508()" FBgn0062646 EP531 EP531 http://flybase.net/reports/FBgn0062646.html gene EP(2)0531 16-Dec-15 2015_12 FBgn0038746 Surf6 Surfeit 6 http://flybase.net/reports/FBgn0038746.html protein_coding_gene 0003676=nucleic acid binding "0022008=neurogenesis, 0042254=ribosome biogenesis" 0005730=nucleolus CG4510 "IPR029190=Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain, IPR007019=Surfeit locus 6" CG4510 16-Dec-15 2015_12 ENSDARG00000035427(surf6l) YKL082C(RRP14) WBGene00022765(ZK546.14) ENSXETG00000005018(surf6) ENSMUSG00000036160(Surf6) ENSG00000148296(SURF6) "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0011140 l(1)Q216 lethal (1) Q216 http://flybase.net/reports/FBgn0011140.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0005669 e(mr) enhancer of morula http://flybase.net/reports/FBgn0005669.html gene 16-Dec-15 2015_12 FBgn0024691 fsf fruitless stimulation factor http://flybase.net/reports/FBgn0024691.html gene 90C factor 16-Dec-15 2015_12 "courtship behavior defective,male" FBgn0261975 CG42806 http://flybase.net/reports/FBgn0261975.html protein_coding_gene CG42806 16-Dec-15 2015_12 FBgn0265341 CR44295 http://flybase.net/reports/FBgn0265341.html non_protein_coding_gene CG44295 CR44295 16-Dec-15 2015_12 FBgn0032205 CG4957 http://flybase.net/reports/FBgn0032205.html protein_coding_gene "IPR029072=YebC-like, IPR017856=Integrase, N-terminal zinc-binding domain-like, IPR002876=Transcriptional regulator TACO1-like, IPR026564=Transcriptional regulator TACO1-like, domain 3" CG4957 16-Dec-15 2015_12 ENSDARG00000062943(zgc:162204) WBGene00021757(Y50D7A.9) ENSXETG00000003249(TACO1) ENSMUSG00000001983(Taco1) ENSG00000136463(TACO1) viable FBgn0025475 prd::Mmus\Pax8 Pax8 http://flybase.net/reports/FBgn0025475.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0264794 CR44024 http://flybase.net/reports/FBgn0264794.html non_protein_coding_gene CR44024 16-Dec-15 2015_12 FBgn0012001 tRNA:V3b:84Dd transfer RNA:val3b:84Dd http://flybase.net/reports/FBgn0012001.html "FBgn0003853, FBgn0011997, FBgn0051502, FBgn0060026" tRNA_gene "0033452=GUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002699.trna1-ValCAC, tRNA:V:CAC:AE002699-a, CR31502, tRNA:V3b, Val-3b, chr3R.trna74-ValCAC, tRNA[Val][[3b]], valine tRNA, tRNA:val3b:84Dd" CR31502 16-Dec-15 2015_12 FBgn0002385 l(3)93Da lethal (3) 93Da http://flybase.net/reports/FBgn0002385.html gene "er1, l(3)er1" 16-Dec-15 2015_12 "lethal,recessive,partially" FBgn0052114 CG32114 http://flybase.net/reports/FBgn0052114.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265644 CR44451 http://flybase.net/reports/FBgn0265644.html non_protein_coding_gene lincRNA.275 CR44451 16-Dec-15 2015_12 FBgn0039402 Vps2 Vacuolar protein sorting 2 http://flybase.net/reports/FBgn0039402.html FBgn0045428 protein_coding_gene "0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0032509=endosome transport via multivesicular body sorting pathway, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0045746=negative regulation of Notch signaling pathway, 0008593=regulation of Notch signaling pathway, 0016197=endosomal transport, 0007034=vacuolar transport" "0000815=ESCRT III complex, 0005769=early endosome, 0005771=multivesicular body" "dvps2, Vps2, vps2, vacuolar protein sorting 2, Did4, CG14542, Dvps2, DmVPS2, NEST:bs02f06" IPR005024=Snf7 family CG14542 16-Dec-15 2015_12 ENSDARG00000053979(bc2) YKL002W(DID4) WBGene00012903(vps-2) ENSXETG00000019244(chmp2a) ENSMUSG00000033916(Chmp2a) ENSG00000130724(CHMP2A) "lethal,lethal - all die before end of embryonic stage,hypoplasia,somatic clone,hyperplasia,somatic clone - Minute background,increased cell death" "embryonic/larval brain,wing disc,somatic clone,somatic clone - Minute background,haltere disc,ventral thoracic disc,epithelium,epithelial cell,actin cytoskeleton | somatic clone - Minute background | third instar larval stage,nucleus | somatic clone - Minute background | third instar larval stage,eye,egg chamber,plasma membrane | somatic clone" DRSC14886 K 0.243924232 -0.808890626 0.86566227 -0.834529864 -2.064803496 -1.4775397 FBgn0266536 CR45097 http://flybase.net/reports/FBgn0266536.html non_protein_coding_gene CR45097 16-Dec-15 2015_12 FBgn0065176 l(3)SH010 lethal (3) SH010 http://flybase.net/reports/FBgn0065176.html gene l(2)SH3 010 16-Dec-15 2015_12 "lethal,recessive" FBgn0005014 dipp-5 defective in phototaxis plasticity 5 http://flybase.net/reports/FBgn0005014.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective,phototaxis defective" FBgn0034901 CG11300 http://flybase.net/reports/FBgn0034901.html FBgn0063096 protein_coding_gene BcDNA:LP08443 CG11300 16-Dec-15 2015_12 FBgn0020647 KrT95D Krueppel target at 95D http://flybase.net/reports/FBgn0020647.html protein_coding_gene 0000042=protein targeting to Golgi CG5405 IPR019381=Phosphofurin acidic cluster sorting protein 1 CG5405 16-Dec-15 2015_12 ENSDARG00000044556(pacs1) WBGene00044077(tag-232) "ENSXETG00000017932(PACS2),ENSXETG00000008416(PACS1)" "ENSMUSG00000021143(Pacs2),ENSMUSG00000024855(Pacs1)" "ENSG00000179364(PACS2),ENSG00000175115(PACS1)" "viable,fertile,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0052710 CG32710 http://flybase.net/reports/FBgn0052710.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053189 CG33189 http://flybase.net/reports/FBgn0053189.html protein_coding_gene CG33189 16-Dec-15 2015_12 viable FBgn0015282 Rpt2 Regulatory particle triple-A ATPase 2 http://flybase.net/reports/FBgn0015282.html protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity, 0016787=hydrolase activity" "0007052=mitotic spindle organization, 0090307=mitotic spindle assembly, 0008283=cell proliferation, 0000022=mitotic spindle elongation, 0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005737=cytoplasm, 0005838=proteasome regulatory particle, 0008540=proteasome regulatory particle, base subcomplex" "PSMC1, Proteasome 26S subunit 4 ATPase, Pros26.4, 5289, p56, CG5289, Dm_Rpt2, DmP26S4, 26S proteasome subunit 4 ATPase, P26s4, S4, unnamed, Proteasome 26S subunit subunit 4 ATPase, Rpt2, pros26.4, dRpt2, Dm-S4-1, proteasome 26S" "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005937=26S proteasome subunit P45, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain" CG5289 16-Dec-15 2015_12 "ENSDARG00000030537(psmc1a),ENSDARG00000070457,ENSDARG00000043561(psmc1b)" YDL007W(RPT2) WBGene00004502(rpt-2) ENSXETG00000015703(psmc1) ENSMUSG00000021178(Psmc1) ENSG00000100764(PSMC1) "meiotic cell cycle defective,male limited,lethal" "testis,spermatocyte" DRSC16799 IEK -2.739142906 -5.993688164 -2.727832802 -4.097045764 4.025543552 3.135853425 FBgn0063414 l(3)3450-I lethal (3) 3450-I http://flybase.net/reports/FBgn0063414.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031454 CG9960 http://flybase.net/reports/FBgn0031454.html "FBgn0052951, FBtr0077737, FBpp0077417, FBtr0077738, FBpp0077418" protein_coding_gene "0008276=protein methyltransferase activity, 0003676=nucleic acid binding" 0032259=methylation "DAMT, CG32951, damt, Dromel_CG9960_CG9958_FBtr007773_snapin_mORF, DNA adenine methyl-transferase, DNA adenine methyltransferase" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR002052=DNA methylase, N-6 adenine-specific, conserved site, IPR004557=Eukaryotic/archaeal PrmC-related" CG9960 16-Dec-15 2015_12 ENSDARG00000035776(zgc:92834) YDR140W(MTQ2) WBGene00016341(C33C12.9) ENSMUSG00000044442(N6amt1) ENSG00000156239(N6AMT1) "lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective" FBgn0011485 l(3)neo55 lethal (3) neo55 http://flybase.net/reports/FBgn0011485.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030506 Lig4 Ligase4 http://flybase.net/reports/FBgn0030506.html protein_coding_gene "0003677=DNA binding, 0005515=protein binding, 0005524=ATP binding, 0003910=DNA ligase (ATP) activity" "0006289=nucleotide-excision repair, 0006273=lagging strand elongation, 0006310=DNA recombination, 0006303=double-strand break repair via nonhomologous end joining, 0051103=DNA ligation involved in DNA repair, 0006266=DNA ligation, 0010212=response to ionizing radiation, 0000723=telomere maintenance, 0071897=DNA biosynthetic process" "0005634=nucleus, 0005694=chromosome, 0032807=DNA ligase IV complex" "Ligase IV, RE37186, ligase4, ligaseIV, lig4, ligIV, ligase IV, CG12176, DNA ligase IV, Ligase 4, DNA ligase 4" "IPR012310=DNA ligase, ATP-dependent, central, IPR012309=DNA ligase, ATP-dependent, C-terminal, IPR012308=DNA ligase, ATP-dependent, N-terminal, IPR001357=BRCT domain, IPR029710=DNA ligase 4, IPR000977=DNA ligase, ATP-dependent, IPR012340=Nucleic acid-binding, OB-fold" CG12176 16-Dec-15 2015_12 ENSDARG00000060620(lig4) YOR005C(DNL4) WBGene00002986(lig-4) ENSXETG00000002654(lig4) ENSMUSG00000049717(Lig4) ENSG00000174405(LIG4) "radiation sensitive,viable,fertile,rescuable maternal effect" FBgn0037177 CG14454 http://flybase.net/reports/FBgn0037177.html FBgn0047187 protein_coding_gene "BcDNA:RE01153, CT34135" CG14454 16-Dec-15 2015_12 FBgn0050096 CG30096 http://flybase.net/reports/FBgn0050096.html protein_coding_gene CG30096 16-Dec-15 2015_12 "viable,fertile" DRSC21744 K 0.241655209 -0.122638804 -0.138504805 -0.712918551 1.889958821 0.966306003 FBgn0001698 l(1)ESHS19 lethal (1) ESHS19 http://flybase.net/reports/FBgn0001698.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267076 CR45520 http://flybase.net/reports/FBgn0267076.html non_protein_coding_gene CR45520 16-Dec-15 2015_12 FBgn0032023 CG14274 http://flybase.net/reports/FBgn0032023.html protein_coding_gene CG14274 16-Dec-15 2015_12 viable FBgn0062574 Mod(var)E1261 Mod(var)E1261 http://flybase.net/reports/FBgn0062574.html gene 0006342=chromatin silencing E1261 16-Dec-15 2015_12 "enhancer of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0053397 5SrRNA:CR33397 5SrRNA:CR33397 http://flybase.net/reports/FBgn0053397.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33397 CR33397 16-Dec-15 2015_12 FBgn0259995 CG40169 http://flybase.net/reports/FBgn0259995.html "FBgn0058169, FBgn0046675" protein_coding_gene "anon-38C.20, 38C.20" 16-Dec-15 2015_12 DRSC01766 I -1.530770784 0.787159639 -0.355660539 0.129055649 -1.191664174 -0.781883301 FBgn0030334 Karl Karl http://flybase.net/reports/FBgn0030334.html protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis "karl, CG4139" "IPR012674=Calycin, IPR011038=Calycin-like" CG4139 16-Dec-15 2015_12 viable FBgn0267756 CR46087 http://flybase.net/reports/FBgn0267756.html non_protein_coding_gene lincRNA.874 CR46087 16-Dec-15 2015_12 FBgn0043460 EP1408 BEST:GH17330 http://flybase.net/reports/FBgn0043460.html gene 0005740=mitochondrial envelope "BEST:GH17330, EP(X)1408, GH17330" 16-Dec-15 2015_12 visible "trichogen cell,ectopic,tormogen cell" FBgn0036423 CG3919 http://flybase.net/reports/FBgn0036423.html protein_coding_gene 0003677=DNA binding "IPR006578=MADF domain, IPR004210=BESS motif" CG3919 16-Dec-15 2015_12 viable FBgn0035707 CG8368 http://flybase.net/reports/FBgn0035707.html protein_coding_gene 0003676=nucleic acid binding RNase H-like "IPR012337=Ribonuclease H-like domain, IPR013520=Exonuclease, RNase T/DNA polymerase III" CG8368 16-Dec-15 2015_12 viable FBgn0039915 Gat GABA transporter http://flybase.net/reports/FBgn0039915.html FBgn0045955 protein_coding_gene "0005332=gamma-aminobutyric acid:sodium symporter activity, 0005328=neurotransmitter:sodium symporter activity" "0071260=cellular response to mechanical stimulus, 0006836=neurotransmitter transport, 0051939=gamma-aminobutyric acid import" "0005886=plasma membrane, 0016021=integral component of membrane, 0097386=glial cell projection" "CG6218, gat, DmGAT, GAT, CG1732, anon-WO0149848.11, dGAT, GABA transporter, CG1732a" IPR000175=Sodium:neurotransmitter symporter CG1732 16-Dec-15 2015_12 "ENSDARG00000039647(zgc:103663),ENSDARG00000045944(zgc:136569),ENSDARG00000041205(si:ch211-280e18.1)" WBGene00004910(snf-11) "ENSXETG00000003633(),ENSXETG00000012105(SLC6A1)" ENSMUSG00000030310(Slc6a1) ENSG00000157103(SLC6A1) viable FBgn0262104 CG42857 http://flybase.net/reports/FBgn0262104.html protein_coding_gene DMG6-MB6.chr3R.10.010 CG42857 16-Dec-15 2015_12 FBgn0053740 snmRNA:430:CR33740 snmRNA:430:CR33740 http://flybase.net/reports/FBgn0053740.html non_protein_coding_gene CR33740 CR33740 16-Dec-15 2015_12 FBgn0053977 CG33977 http://flybase.net/reports/FBgn0053977.html protein_coding_gene IPR013174=Dolichol-phosphate mannosyltransferase subunit 3 CG33977 16-Dec-15 2015_12 ENSDARG00000058650(dpm3) WBGene00009219(dpm-3) ENSXETG00000019426(dpm3) ENSMUSG00000042737(Dpm3) ENSG00000179085(DPM3) FBgn0053777 CG33777 http://flybase.net/reports/FBgn0053777.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33777 16-Dec-15 2015_12 FBgn0085774 CR40779 http://flybase.net/reports/FBgn0085774.html FBan0040779 rRNA_gene CR40779 16-Dec-15 2015_12 FBgn0063508 En(tc) Enhancer of terminal conversion http://flybase.net/reports/FBgn0063508.html gene 16-Dec-15 2015_12 FBgn0034432 CG7461 http://flybase.net/reports/FBgn0034432.html protein_coding_gene "0017099=very-long-chain-acyl-CoA dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" 0055114=oxidation-reduction process "0005811=lipid particle, 0005875=microtubule associated complex" "Drosophila very-long chain ACAD, cg7461" "IPR006089=Acyl-CoA dehydrogenase, conserved site, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain" CG7461 16-Dec-15 2015_12 ENSDARG00000016687(acadvl) WBGene00017125(acdh-12) ENSXETG00000001719(acad9) ENSMUSG00000018574(Acadvl) ENSG00000072778(ACADVL) "viable,fertile" FBgn0267353 BG02514 http://flybase.net/reports/FBgn0267353.html gene 16-Dec-15 2015_12 "short lived,female,male,heat stress response defective,starvation stress response defective,chemosensitive behavior defective" macrochaeta FBgn0264650 littoral littoral http://flybase.net/reports/FBgn0264650.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0052552 CG32552 http://flybase.net/reports/FBgn0052552.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060756 l(3)S063913b lethal (3) S063913b http://flybase.net/reports/FBgn0060756.html gene 0639/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0265725 CG44532 http://flybase.net/reports/FBgn0265725.html protein_coding_gene lincRNA.970 CG44532 16-Dec-15 2015_12 FBgn0025744 maz matzerath http://flybase.net/reports/FBgn0025744.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant,viable" "central nervous system,wing vein,ectopic" FBgn0030804 CG13002 http://flybase.net/reports/FBgn0030804.html protein_coding_gene "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG13002 16-Dec-15 2015_12 viable FBgn0261634 CG42717 http://flybase.net/reports/FBgn0261634.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "DMG4-MB6.chr3L.27.007, DMG4-MB6.chr3L.27.007-MIP19202, HDC10387" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42717 16-Dec-15 2015_12 FBgn0004943 agl angle winglike http://flybase.net/reports/FBgn0004943.html gene angle wing 16-Dec-15 2015_12 "visible,recessive" wing FBgn0030968 CG7322 http://flybase.net/reports/FBgn0030968.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002198=Short-chain dehydrogenase/reductase SDR" CG7322 16-Dec-15 2015_12 "YIR035C(),YIR036C(IRC24)" WBGene00000984(dhs-21) ENSXETG00000004630(dcxr) "ENSMUSG00000039450(Dcxr),ENSMUSG00000025150(Cbr2)" ENSG00000169738(DCXR) viable FBgn0266842 CR45304 http://flybase.net/reports/FBgn0266842.html non_protein_coding_gene CR45304 16-Dec-15 2015_12 FBgn0037489 CG1234 http://flybase.net/reports/FBgn0037489.html protein_coding_gene 0005634=nucleus "IPR005612=CCAAT-binding factor, IPR016024=Armadillo-type fold, IPR016903=Nucleolar complex-associated protein 3, IPR011501=Nucleolar complex-associated" CG1234 16-Dec-15 2015_12 ENSDARG00000002487(noc3l) YLR002C(NOC3) WBGene00016508(C37H5.5) ENSXETG00000020975(NOC3L) ENSMUSG00000024999(Noc3l) ENSG00000173145(NOC3L) "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0259748 CG42397 http://flybase.net/reports/FBgn0259748.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG42397 16-Dec-15 2015_12 FBgn0014870 Psi P-element somatic inhibitor http://flybase.net/reports/FBgn0014870.html protein_coding_gene "0003729=mRNA binding, 0005515=protein binding" "0006397=mRNA processing, 0007283=spermatogenesis, 0048024=regulation of mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0048025=negative regulation of mRNA splicing, via spliceosome" "0005634=nucleus, 0005685=U1 snRNP" "PSI, P-element somatic inhibitor protein, P element Somatic Inhibitor, CG8912, EG:EG0003.2" "IPR015096=Domain of unknown function DUF1897, IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG8912 16-Dec-15 2015_12 "ENSDARG00000029248(fubp1),ENSDARG00000026489(zgc:163038)" "WBGene00007534(C12D8.1),WBGene00022738(ZK418.9),WBGene00016489(C36E6.1),WBGene00019692(M01A10.1)" "ENSXETG00000013137(fubp1),ENSXETG00000021862(KHSRP),ENSXETG00000001344(FUBP3)" "ENSMUSG00000007670(Khsrp),ENSMUSG00000028034(Fubp1),ENSMUSG00000026843(Fubp3)" "ENSG00000088247(KHSRP),ENSG00000162613(FUBP1),ENSG00000107164(FUBP3)" " embryonic stage | early , embryonic stage -- adult stage , oogenesis stage && adult stage | female , embryonic stage | 2-8 hr " ovary

"wild-type,courtship behavior defective,mating defective,sterile,male,meiotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" "spermatid,onion stage spermatid,testis,trichogen cell" DRSC07519 I -1.171608483 1.756830099 0.162208376 0.304035022 -0.703060183 -0.937862654 FBgn0267303 CR45739 http://flybase.net/reports/FBgn0267303.html non_protein_coding_gene CR45739 16-Dec-15 2015_12 FBgn0085515 CG40758 http://flybase.net/reports/FBgn0085515.html FBan0040758 protein_coding_gene 16-Dec-15 2015_12 FBgn0265065 CR44176 http://flybase.net/reports/FBgn0265065.html non_protein_coding_gene CR44176 16-Dec-15 2015_12 FBgn0036337 AdenoK Adenosine Kinase http://flybase.net/reports/FBgn0036337.html protein_coding_gene "0016773=phosphotransferase activity, alcohol group as acceptor, 0004001=adenosine kinase activity" "0006166=purine ribonucleoside salvage, 0006167=AMP biosynthetic process" "0005829=cytosol, 0005654=nucleoplasm" "CG11255, DmAdk2" "IPR011611=Carbohydrate kinase PfkB, IPR029056=Ribokinase-like, IPR002173=Carbohydrate/puine kinase, PfkB, conserved site, IPR001805=Adenosine kinase" CG11255 16-Dec-15 2015_12 "ENSDARG00000039429(adka),ENSDARG00000018258(adkb)" YJR105W(ADO1) WBGene00011128(R07H5.8) ENSXETG00000020595(adk) ENSMUSG00000039197(Adk) ENSG00000156110(ADK) "viable,fertile,long lived" FBgn0060832 l(3)S050115b lethal (3) S050115b http://flybase.net/reports/FBgn0060832.html gene "l(3)s050115, 0501/15" 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0014047 Su(tor)2-191 Su(tor)2-191 http://flybase.net/reports/FBgn0014047.html gene 16-Dec-15 2015_12 FBgn0264520 ff4 http://flybase.net/reports/FBgn0264520.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male,mitotic cell cycle defective" spermatid FBgn0084352 l(3)S012805 l(3)S012805 http://flybase.net/reports/FBgn0084352.html gene 16-Dec-15 2015_12 FBgn0024621 meso2 meso2 http://flybase.net/reports/FBgn0024621.html FBgn0024481 gene Clone2 16-Dec-15 2015_12 FBgn0032434 CG5421 http://flybase.net/reports/FBgn0032434.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033180=proton-transporting V-type ATPase, V1 domain" "IPR008388=ATPase, V1 complex, subunit S1" CG5421 16-Dec-15 2015_12 FBgn0001065 fs(3)T female sterile of Tabriz http://flybase.net/reports/FBgn0001065.html gene 16-Dec-15 2015_12 "female sterile,recessive,eye color defective" "female reproductive system,pigment cell" FBgn0038861 CG7009 http://flybase.net/reports/FBgn0038861.html protein_coding_gene "0008650=rRNA (uridine-2'-O-)-methyltransferase activity, 0008175=tRNA methyltransferase activity" "0008033=tRNA processing, 0001510=RNA methylation, 0000154=rRNA modification" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR028590=tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7, IPR015507=Ribosomal RNA large subunit methyltransferase E, IPR002877=Ribosomal RNA methyltransferase FtsJ domain" CG7009 16-Dec-15 2015_12 YBR061C(TRM7) ENSXETG00000006939(FTSJ3) "viable,fertile" FBgn0083082 l(4)B6-C1 lethal (4) B6-C1 http://flybase.net/reports/FBgn0083082.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005739 l(1)TK229 lethal (1) TK229 http://flybase.net/reports/FBgn0005739.html gene l229 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0020294 ko knockout http://flybase.net/reports/FBgn0020294.html protein_coding_gene 0008045=motor neuron axon guidance CG10573 "IPR019391=Storkhead-box protein, winged-helix domain" CG10573 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective" "RP5 motor neuron,RP3 motor neuron" FBgn0064237 Idgf5 Imaginal disc growth factor 5 http://flybase.net/reports/FBgn0064237.html FBgn0034333 protein_coding_gene "0004568=chitinase activity, 0008084=imaginal disc growth factor receptor binding" "0005975=carbohydrate metabolic process, 0006032=chitin catabolic process, 0007444=imaginal disc development" 0005576=extracellular region "DmIDGF5, IDGF-5, IDGF, Cht14, CG5154, IDGF5, imaginal disc growth factor 5" "IPR015520=Imaginal disc growth factor, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR029070=Chitinase insertion domain, IPR017853=Glycoside hydrolase superfamily, IPR011583=Chitinase II" CG5154 16-Dec-15 2015_12 viable FBgn0030339 Cyp28c1 Cyp28c1 http://flybase.net/reports/FBgn0030339.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "28c1, cytochrome P450, CG1895" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG1895 16-Dec-15 2015_12 YHR007C(ERG11) FBgn0262375 mir-1005 mir-1005 stem loop http://flybase.net/reports/FBgn0262375.html "FBgn0250801, FBgn0262188" miRNA_gene "dme-mir-1005, miR-1005, CR42895" CR42895 16-Dec-15 2015_12 viable FBgn0036617 Cpr72Ea Cuticular protein 72Ea http://flybase.net/reports/FBgn0036617.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG4818 IPR000618=Insect cuticle protein CG4818 16-Dec-15 2015_12 "viable,fertile" FBgn0026083 tyf twenty-four http://flybase.net/reports/FBgn0026083.html FBgn0026082 protein_coding_gene 0005515=protein binding "0045475=locomotor rhythm, 0042742=defense response to bacterium, 0045727=positive regulation of translation" "EG:EG0007.4, CG485, Twenty-four, TWENTY-FOUR, twenty four, TYF, CG4857, EG:EG0007.12" CG4857 16-Dec-15 2015_12 "circadian behavior defective,locomotor rhythm defective,viable,fertile,recessive,circadian rhythm defective" embryonic/larval hemocyte | third instar larval stage FBgn0019772 l(1)47 lethal (1) 47 http://flybase.net/reports/FBgn0019772.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085277 CG34248 http://flybase.net/reports/FBgn0085277.html protein_coding_gene CG34248 16-Dec-15 2015_12 FBgn0020314 anon-95ABa anon-95ABa http://flybase.net/reports/FBgn0020314.html gene "10A2, unnamed" 16-Dec-15 2015_12 FBgn0003102 PL(2)sp-S3 Polygenic locus sternopleural S3 http://flybase.net/reports/FBgn0003102.html gene "PL(2)sp[S3], II" 16-Dec-15 2015_12 FBgn0039324 CG10553 http://flybase.net/reports/FBgn0039324.html protein_coding_gene CT29612 "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG10553 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0022310 l(1)J67.3 lethal (1) J67.3 http://flybase.net/reports/FBgn0022310.html gene J67.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0010461 l(2)00297 lethal (2) 00297 http://flybase.net/reports/FBgn0010461.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011144 l(1)Q220 lethal (1) Q220 http://flybase.net/reports/FBgn0011144.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0264473 CR43881 http://flybase.net/reports/FBgn0264473.html non_protein_coding_gene CR43881 16-Dec-15 2015_12 FBgn0035850 Atg18a Autophagy-related 18a http://flybase.net/reports/FBgn0035850.html protein_coding_gene "0080025=phosphatidylinositol-3,5-bisphosphate binding, 0032266=phosphatidylinositol-3-phosphate binding" "0050688=regulation of defense response to virus, 0051607=defense response to virus, 1902350=cellular response to chloroquine, 0035096=larval midgut cell programmed cell death, 0009267=cellular response to starvation, 0016236=macroautophagy, 0014067=negative regulation of phosphatidylinositol 3-kinase signaling, 0000045=autophagic vacuole assembly, 0006914=autophagy, 0010506=regulation of autophagy, 0035069=larval midgut histolysis" "0005829=cytosol, 0005737=cytoplasm, 0034045=pre-autophagosomal structure membrane, 0000421=autophagic vacuole membrane" "CG7986, Atg18a, Autophagy-specific gene 18, ATG18.1, ATG18, Atg18, atg18, Autophagy-specific gene 18a" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG7986 16-Dec-15 2015_12 "ENSDARG00000037871(wipi2),ENSDARG00000040657(wipi1)" YFR021W(ATG18) WBGene00018294(atg-18) ENSXETG00000003087(BC087784.1) "ENSMUSG00000029578(Wipi2),ENSMUSG00000041895(Wipi1)" "ENSG00000157954(WIPI2),ENSG00000070540(WIPI1)" "lethal - all die before end of larval stage,recessive,stress response defective,neuroanatomy defective,decreased cell growth,some die during larval stage,viable,immune response defective" "embryonic/larval midgut,neuromuscular junction,NMJ bouton,embryonic/larval fat body,embryonic/larval salivary gland,somatic clone | third instar larval stage" FBgn0011915 tRNA:M2:48Ba transfer RNA:met2:48Ba http://flybase.net/reports/FBgn0011915.html "FBgn0003807, FBgn0050255, FBgn0060137" tRNA_gene "0033436=AUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:M:CAT:AE002787-d, chr2R.trna16-MetCAT, AE002787.trna34-MetCAT, CR30255, tRNA:met2:48Ba" CR30255 16-Dec-15 2015_12 FBgn0069109 mus315 mutagen-sensitive 315 http://flybase.net/reports/FBgn0069109.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0260775 DnaJ-60 DnaJ-like-60 http://flybase.net/reports/FBgn0260775.html "FBgn0020129, FBgn0046451, FBgn0260769" protein_coding_gene 0051082=unfolded protein binding "0007283=spermatogenesis, 0006457=protein folding" 0016020=membrane "CG42567, DmJ60, anon-WO0172774.147, DnaJ60, CG12240" IPR001623=DnaJ domain CG42567 16-Dec-15 2015_12 FBgn0053415 5SrRNA:CR33415 5SrRNA:CR33415 http://flybase.net/reports/FBgn0053415.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33415 CR33415 16-Dec-15 2015_12 FBgn0001687 l(1)ESHS8 lethal (1) ESHS8 http://flybase.net/reports/FBgn0001687.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052596 CG32596 http://flybase.net/reports/FBgn0052596.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035986 CG4022 http://flybase.net/reports/FBgn0035986.html protein_coding_gene 0046427=positive regulation of JAK-STAT cascade IPR012981=PIH1 family CG4022 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0064166 l(3)AP1 lethal (3) AP1 http://flybase.net/reports/FBgn0064166.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010331 Sebp344 Secretion enhancer-binding protein 344 http://flybase.net/reports/FBgn0010331.html gene 16-Dec-15 2015_12 FBgn0265932 CR44721 http://flybase.net/reports/FBgn0265932.html non_protein_coding_gene lincRNA.508 CR44721 16-Dec-15 2015_12 FBgn0053251 CG33251 http://flybase.net/reports/FBgn0053251.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000449 dib disembodied http://flybase.net/reports/FBgn0000449.html FBgn0035492 protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding, 0042767=ecdysteroid 22-hydroxylase activity, 0005506=iron ion binding" "0007391=dorsal closure, 0055114=oxidation-reduction process, 0006697=ecdysone biosynthetic process, 0007417=central nervous system development, 0008205=ecdysone metabolic process, 0008362=chitin-based embryonic cuticle biosynthetic process, 0008258=head involution, 0007494=midgut development" "0005739=mitochondrion, 0005743=mitochondrial inner membrane" "Dib, CG12028, l(3)SH14, l(3)dib, l(3)64Ak, 302a1, Cyp302a1, Cyp, Disembodied, cytochrome P450, CYP302A1" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG12028 16-Dec-15 2015_12 " embryonic stage | early , oogenesis stage | stage S8-11 && adult stage | female , embryonic stage | extended germ band , larval stage | third instar , embryonic stage | stage 14-17 " "

anterior , follicle cell

, embryonic epidermis

, ring gland && prothoracic segment

, ring gland && embryonic prothoracic segment

, organism | striped & posterior

" "viable,fertile,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,memory defective,RU486 conditional,large body,developmental rate defective" "presumptive embryonic/larval central nervous system,dorsal closure embryo,stage 14 embryo,midgut primordium,hindgut proper primordium,midgut constriction,yolk granule,embryonic/first instar larval cuticle,denticle belt,dorsal hair,cephalopharyngeal skeleton,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,commissure,longitudinal connective,glial cell,midline glial cell,ectopic,embryonic head,pupa,mouth hooks" FBgn0000844 fs(1)M31 female sterile (1) M31 http://flybase.net/reports/FBgn0000844.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0025720 Ate1 Ate1 http://flybase.net/reports/FBgn0025720.html FBgn0021941 protein_coding_gene 0004057=arginyltransferase activity "0006511=ubiquitin-dependent protein catabolic process, 0016598=protein arginylation" "Dm-Ate1, l(2)k10809, CG9204, ate1, ATE1, Ate" "IPR016181=Acyl-CoA N-acyltransferase, IPR017137=Arginine-tRNA-protein transferase 1, eukaryotic, IPR030700=Arginine-tRNA-protein transferase, IPR007471=Arginine-tRNA-protein transferase, N-terminal, IPR007472=Arginine-tRNA-protein transferase, C-terminal" CG9204 16-Dec-15 2015_12 YGL017W(ATE1) WBGene00010615(K07A1.9) ENSXETG00000015591(ATE1) ENSMUSG00000030850(Ate1) ENSG00000107669(ATE1) "lethal,recessive,viable" FBgn0033544 CG7220 http://flybase.net/reports/FBgn0033544.html "FBgn0045804, FBgn0047296" protein_coding_gene 0004842=ubiquitin-protein transferase activity "0006513=protein monoubiquitination, 0006508=proteolysis" "BEST:GH28095, BcDNA:GH28095" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG7220 16-Dec-15 2015_12 "ENSDARG00000045360(flj11011l),ENSDARG00000044923(ube2w)" WBGene00006711(ubc-16) ENSXETG00000011827(UBE2W) ENSMUSG00000025939(Ube2w) ENSG00000104343(UBE2W) "lethal,viable" FBgn0033972 Ciao1 Ciao1 http://flybase.net/reports/FBgn0033972.html protein_coding_gene "0016226=iron-sulfur cluster assembly, 0022008=neurogenesis" 0097361=CIA complex "CG12797, CiaO1" "IPR028608=Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat" CG12797 16-Dec-15 2015_12 ENSDARG00000059212(ciao1) YDR267C(CIA1) WBGene00012479(Y18D10A.9) ENSXETG00000004336(wdr39) ENSMUSG00000003662(Ciao1) ENSG00000144021(CIAO1) "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0261552 ps pasilla http://flybase.net/reports/FBgn0261552.html "FBgn0026188, FBgn0063674, FBgn0042204, FBgn0037695, FBgn0037693, FBgn0037692, FBgn0024515, FBan0008144, FBgn0037694" protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome" "0005829=cytosol, 0005634=nucleus" "CG8144, CG16765, Pasilla, PS, CG42670, cg8144, CG16777, lethal (3) 10615, l(3)10615, CG18509, BcDNA:RE47781, EP(3)3406, NOVA1, CG16776" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG42670 16-Dec-15 2015_12 "ENSDARG00000020178(nova1),ENSDARG00000017673(nova2)" "ENSXETG00000010244(),ENSXETG00000019101(nova1)" "ENSMUSG00000030411(Nova2),ENSMUSG00000021047(Nova1)" "ENSG00000139910(NOVA1),ENSG00000104967(NOVA2)" """DRSC16388, DRSC22989"" " IEK FBgn0264448 CR43866 http://flybase.net/reports/FBgn0264448.html non_protein_coding_gene CR43866 16-Dec-15 2015_12 FBgn0039336 CG4553 http://flybase.net/reports/FBgn0039336.html protein_coding_gene IPR010487=Neugrin/Rrg9 CG4553 16-Dec-15 2015_12 ENSDARG00000061314(si:ch211-199o1.5) viable FBgn0082358 HM17 HM17 http://flybase.net/reports/FBgn0082358.html gene 16-Dec-15 2015_12 FBgn0267225 CR45665 http://flybase.net/reports/FBgn0267225.html non_protein_coding_gene CR45665 16-Dec-15 2015_12 FBgn0082910 60-15 60-15 http://flybase.net/reports/FBgn0082910.html gene 16-Dec-15 2015_12 FBgn0023128 anon-10Aaa anon-10Aaa http://flybase.net/reports/FBgn0023128.html gene 20 16-Dec-15 2015_12 FBgn0029825 CG12728 http://flybase.net/reports/FBgn0029825.html protein_coding_gene "X-ray repair cross-complementing protein 4, XRCC4" CG12728 16-Dec-15 2015_12 ENSG00000187736(NHEJ1) viable FBgn0027644 l(3)CL-R lethal (3) Cell Lethal Right http://flybase.net/reports/FBgn0027644.html gene CL3R 16-Dec-15 2015_12 lethal FBgn0262836 CG43200 http://flybase.net/reports/FBgn0262836.html protein_coding_gene nc_5744.a CG43200 16-Dec-15 2015_12 FBgn0053358 5SrRNA:CR33358 5SrRNA:CR33358 http://flybase.net/reports/FBgn0053358.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33358 CR33358 16-Dec-15 2015_12 FBgn0000008 a arc http://flybase.net/reports/FBgn0000008.html "FBgn0034701, FBgn0034702" protein_coding_gene 0048749=compound eye development "0016324=apical plasma membrane, 0005912=adherens junction" "bran, Arc, CG6741, CG13505, broad angular" IPR001478=PDZ domain CG6741 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage >=6 , larval stage | third instar , embryonic stage | early , embryonic stage | stage >12 , embryonic stage | stage >=10 " " embryonic/larval salivary gland

, posterior midgut proper primordium

, embryonic/larval foregut

, morphogenetic furrow

,

anterior posterior gradient , embryonic/larval hindgut

, Malpighian tubule

" " embryonic stage , embryonic stage | stage >=6 , embryonic stage | stage >13 , embryonic stage | stage >=10 , larval stage | third instar " " embryonic/larval salivary gland

, posterior midgut proper primordium

, embryonic/larval foregut

, embryonic/larval hindgut

, Malpighian tubule

, morphogenetic furrow

" "lethal,visible,dominant,viable,recessive,wild-type,sterile,lethal - all die before end of pupal stage,some die during pupal stage" "wing,eye,ommatidium,posterior scutellar bristle,macrochaeta,crossvein" FBgn0025498 l(3)73Bf lethal (3) 73Bf http://flybase.net/reports/FBgn0025498.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065665 l(2)SH0701 lethal (2) SH0701 http://flybase.net/reports/FBgn0065665.html gene l(2)SH2 0701 16-Dec-15 2015_12 "lethal,recessive" FBgn0265375 CR44316 http://flybase.net/reports/FBgn0265375.html non_protein_coding_gene lincRNA.291 CR44316 16-Dec-15 2015_12 FBgn0034828 CG13545 http://flybase.net/reports/FBgn0034828.html protein_coding_gene CG13545 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0002096 l(2)57Cb lethal (2) 57Cb http://flybase.net/reports/FBgn0002096.html gene 16-Dec-15 2015_12 lethal FBgn0016885 l(2)39DEj lethal (2) 39DEj http://flybase.net/reports/FBgn0016885.html gene D244 16-Dec-15 2015_12 lethal FBgn0001897 l(2)21Fc lethal (2) 21Fc http://flybase.net/reports/FBgn0001897.html gene "l(2)neh11, l(2)neh-11" 16-Dec-15 2015_12 lethal FBgn0265068 CR44179 http://flybase.net/reports/FBgn0265068.html non_protein_coding_gene CR44179 16-Dec-15 2015_12 FBgn0052075 CG32075 http://flybase.net/reports/FBgn0052075.html FBgn0036119 protein_coding_gene 0022008=neurogenesis CG6316 IPR007174=Las1-like CG32075 16-Dec-15 2015_12 ENSDARG00000062457(LOC561321) WBGene00012393(Y6B3B.9) ENSMUSG00000057421(Las1l) ENSG00000001497(LAS1L) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0041635 EM3-1 EM3-1 http://flybase.net/reports/FBgn0041635.html gene 16-Dec-15 2015_12 FBgn0040031 CG12061 http://flybase.net/reports/FBgn0040031.html "FBgn0058148, FBan0012061" protein_coding_gene "0008273=calcium, potassium:sodium antiporter activity" 0055085=transmembrane transport 0016021=integral component of membrane CG40148 "IPR004837=Sodium/calcium exchanger membrane region, IPR004481=Sodium/potassium/calcium exchanger" CG12061 16-Dec-15 2015_12 YDL206W() viable FBgn0261627 CG42710 http://flybase.net/reports/FBgn0261627.html protein_coding_gene HDC01517 CG42710 16-Dec-15 2015_12 FBgn0060681 l(3)S076304 lethal (3) S076304 http://flybase.net/reports/FBgn0060681.html gene 0763/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0014856 Gyc89A Guanylyl cyclase at 89A http://flybase.net/reports/FBgn0014856.html gene "0004383=guanylate cyclase activity, 0004872=receptor activity" 0007165=signal transduction 0005886=plasma membrane DrGC-2 16-Dec-15 2015_12 FBgn0031951 r2d2 r2d2 http://flybase.net/reports/FBgn0031951.html protein_coding_gene 0003725=double-stranded RNA binding "0035087=siRNA loading onto RISC involved in RNA interference, 0070918=production of small RNA involved in gene silencing by RNA, 0070868=heterochromatin organization involved in chromatin silencing, 0030422=production of siRNA involved in RNA interference, 0070920=regulation of production of small RNA involved in gene silencing by RNA, 0051607=defense response to virus, 0030713=ovarian follicle cell stalk formation" "0005737=cytoplasm, 0005634=nucleus, 0016442=RISC complex" "CG7138, R2d2, R2D2, cg7138" IPR014720=Double-stranded RNA-binding domain CG7138 16-Dec-15 2015_12 "immune response defective,recessive,lethal,maternal effect,suppressor of variegation,dominant,conditional,visible,partially lethal - majority die,some die during pupal stage" "interfollicle cell,follicle cell,egg chamber,somatic clone,trichogen cell" FBgn0045045 fs(1)38 female sterile (1) 38 http://flybase.net/reports/FBgn0045045.html gene "0007306=eggshell chorion assembly, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile "egg,chorion" FBgn0259538 GG01022 http://flybase.net/reports/FBgn0259538.html gene 16-Dec-15 2015_12 visible "leg,unguis,tarsal segment,arista" FBgn0065955 l(2)SH0062 lethal (2) SH0062 http://flybase.net/reports/FBgn0065955.html gene l(2)SH2 0062 16-Dec-15 2015_12 "lethal,recessive" FBgn0037517 CG10086 http://flybase.net/reports/FBgn0037517.html protein_coding_gene "IPR011022=Arrestin C-terminal-like domain, IPR014756=Immunoglobulin E-set, IPR011021=Arrestin-like, N-terminal" CG10086 16-Dec-15 2015_12 ENSG00000197070(ARRDC1) viable FBgn0260077 2L0944 http://flybase.net/reports/FBgn0260077.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0021960 l(2)k10127 lethal (2) k10127 http://flybase.net/reports/FBgn0021960.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058441 CR40441 http://flybase.net/reports/FBgn0058441.html FBan0040441 pseudogene_attribute CG40441 CR40441 16-Dec-15 2015_12 FBgn0261538 CG42662 http://flybase.net/reports/FBgn0261538.html protein_coding_gene CG42662 16-Dec-15 2015_12 FBgn0001260 inaA inactivation no afterpotential A http://flybase.net/reports/FBgn0001260.html gene inactivation-no-afterpotential-A 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0265547 CR44397 http://flybase.net/reports/FBgn0265547.html non_protein_coding_gene lincRNA.176 CR44397 16-Dec-15 2015_12 FBgn0037751 topi matotopetli http://flybase.net/reports/FBgn0037751.html protein_coding_gene "0005515=protein binding, 0046872=metal ion binding, 0003676=nucleic acid binding, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0007140=male meiosis, 0007283=spermatogenesis, 0051039=positive regulation of transcription during meiosis" "0000790=nuclear chromatin, 0005634=nucleus" "CG8484, Topi" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG8484 16-Dec-15 2015_12 "meiotic cell cycle defective,male,male sterile,viable,female fertile" "spermatid,secondary spermatocyte,nuclear chromosome & primary spermatocyte,primary spermatocyte & nuclear chromosome,primary spermatocyte & nuclear chromosomeby10)" FBgn0022312 l(1)H30.1 lethal (1) H30.1 http://flybase.net/reports/FBgn0022312.html gene H30.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0029897 RpL17 Ribosomal protein L17 http://flybase.net/reports/FBgn0029897.html FBgn0026274 protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0000022=mitotic spindle elongation, 0051298=centrosome duplication" 0022625=cytosolic large ribosomal subunit "ribosomal protein L17, Rpl17, anon-EST:Posey276, CG3203" "IPR005721=Ribosomal protein L22/L17, eukaryotic/archaeal, IPR001063=Ribosomal protein L22/L17, IPR018260=Ribosomal protein L22/L17, conserved site" CG3203 16-Dec-15 2015_12 ENSDARG00000057556(zgc:65996) "YKL180W(RPL17A),YJL177W(RPL17B)" WBGene00004429(rpl-17) ENSXETG00000020308(Q6DEU4_XENTR) "ENSMUSG00000062328(Rpl17),ENSMUSG00000066475(Rpl17-ps3),ENSMUSG00000069392(Gm10268),ENSMUSG00000072489(Gm10362),ENSMUSG00000066714,ENSMUSG00000063986" "ENSG00000212664,ENSG00000175333" "viable,fertile,lethal" DRSC18293 IEK -1.788815557 -1.577283294 -0.596978383 -4.520636137 1.872277332 2.38221562 FBgn0028119 l(3)S061207 lethal (3) S061207 http://flybase.net/reports/FBgn0028119.html FBgn0060444 gene "0612/07, l(3)S122612a, 0671/10, 1226/12" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085788 CR41504 http://flybase.net/reports/FBgn0085788.html FBan0041504 pseudogene_attribute CR41504 16-Dec-15 2015_12 FBgn0005390 fs(1)M3 female sterile (1) M3 http://flybase.net/reports/FBgn0005390.html "FBgn0000816, FBgn0004681, FBgn0029829" protein_coding_gene "0007304=chorion-containing eggshell formation, 0007362=terminal region determination, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "0005576=extracellular region, 0009897=external side of plasma membrane" "fs(1)ph, fs(1)K646, Polehole, Fs(1)K646, fs(1)phl, fs(1)pole hole, CG4790, fs(1)polehole" CG4790 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,maternal effect,viable" "vitelline membrane,egg,cephalopharyngeal skeleton,maternal effect,head,anterior,telson,abdominal segment 8,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,labrum,ocular segment,cephalic furrow,terminalia,embryo,posterior,embryonic abdominal segment 8" FBgn0052277 CG32277 http://flybase.net/reports/FBgn0052277.html FBgn0035418 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG11531, SP183" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG32277 16-Dec-15 2015_12 FBgn0085400 CG34371 http://flybase.net/reports/FBgn0085400.html "FBgn0034831, FBgn0034830, FBgn0034832, FBgn0050188" protein_coding_gene "34371, CG13547, CG13548, CT32922, CT32921, CG13546, CG30188" "IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG34371 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" viable FBgn0027132 l(3)B5-1 lethal (3) B5-1 http://flybase.net/reports/FBgn0027132.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265980 CR44759 http://flybase.net/reports/FBgn0265980.html non_protein_coding_gene lincRNA.374 CR44759 16-Dec-15 2015_12 FBgn0060937 l(3)S040708b lethal (3) S040708b http://flybase.net/reports/FBgn0060937.html gene 0407/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0041144 l(1)1Bm lethal (1) 1Bm http://flybase.net/reports/FBgn0041144.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030657 cerv cervantes http://flybase.net/reports/FBgn0030657.html protein_coding_gene 0019789=SUMO transferase activity "0006281=DNA repair, 0000724=double-strand break repair via homologous recombination" "0030915=Smc5-Smc6 complex, 0005634=nucleus" "CG15645, Cervantes" IPR026846=E3 SUMO-protein ligase Nse2 (Mms21) CG15645 16-Dec-15 2015_12 WBGene00022881(ZK1248.11) ENSMUSG00000059586(Nsmce2) ENSG00000156831(NSMCE2) viable FBgn0036576 CG5151 http://flybase.net/reports/FBgn0036576.html protein_coding_gene CG5151 16-Dec-15 2015_12 "viable,fertile" FBgn0016855 l(1)N36 lethal (1) N36 http://flybase.net/reports/FBgn0016855.html gene N36 16-Dec-15 2015_12 "lethal,recessive" FBgn0027505 Rab3-GAP Rab3 GTPase activating protein http://flybase.net/reports/FBgn0027505.html protein_coding_gene "0030234=enzyme regulator activity, 0046982=protein heterodimerization activity, 0005096=GTPase activator activity" "0016192=vesicle-mediated transport, 0007298=border follicle cell migration, 0007269=neurotransmitter secretion, 0060025=regulation of synaptic activity, 0043087=regulation of GTPase activity" 0008021=synaptic vesicle "rab3-GAP, Rab3-GAP, CG7061, BcDNA:LD23336" "IPR029257=Rab3GAP regulatory subunit, C-terminal, IPR026059=Rab3-GAP regulatory subunit" CG7061 16-Dec-15 2015_12 ENSDARG00000044136(rab3gap2) WBGene00004318(rbg-2) ENSXETG00000002728(RAB3GAP2) ENSMUSG00000039318 ENSG00000118873(RAB3GAP2) "neurophysiology defective,chemical sensitive,cell migration defective,viable" border follicle cell FBgn0037981 Spt3 Spt3 http://flybase.net/reports/FBgn0037981.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0004402=histone acetyltransferase activity, 0046982=protein heterodimerization activity" "0006367=transcription initiation from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0043966=histone H3 acetylation" "0005634=nucleus, 0000123=histone acetyltransferase complex, 0005669=transcription factor TFIID complex, 0000124=SAGA complex" "TFIID, CG3169, dSpt3, SPT3" "IPR003195=Transcription initiation factor IID, 18kDa subunit, IPR009072=Histone-fold" CG3169 16-Dec-15 2015_12 ENSDARG00000002776(supt3h) ENSXETG00000001404(supt3h) ENSMUSG00000038954(Supt3h) ENSG00000196284(SUPT3H) viable FBgn0005742 l(1)TK234 lethal (1) TK234 http://flybase.net/reports/FBgn0005742.html gene l234 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0267533 CR45873 http://flybase.net/reports/FBgn0267533.html non_protein_coding_gene CR45873 16-Dec-15 2015_12 FBgn0033069 CG8335 http://flybase.net/reports/FBgn0033069.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 0003743=translation initiation factor activity" "0006413=translational initiation, 0016579=protein deubiquitination" 0005852=eukaryotic translation initiation factor 3 complex "eIF3-S5, eIF3f" "IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR027531=Eukaryotic translation initiation factor 3 subunit F, IPR024969=Rpn11/EIF3F, C-terminal" CG8335 16-Dec-15 2015_12 WBGene00001229(eif-3.F) viable FBgn0040124 l(2)23CDd lethal (2) 23CDd http://flybase.net/reports/FBgn0040124.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000883 fs(1)M81 female sterile (1) M81 http://flybase.net/reports/FBgn0000883.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0264262 CR43762 http://flybase.net/reports/FBgn0264262.html non_protein_coding_gene CR43762 16-Dec-15 2015_12 FBgn0033682 CG18344 http://flybase.net/reports/FBgn0033682.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025631 moody moody http://flybase.net/reports/FBgn0025631.html FBgn0041254 protein_coding_gene "0004930=G-protein coupled receptor activity, 0008502=melatonin receptor activity" "0060857=establishment of glial blood-brain barrier, 0007419=ventral cord development, 0048149=behavioral response to ethanol, 0019991=septate junction assembly, 0048148=behavioral response to cocaine, 0007186=G-protein coupled receptor signaling pathway, 0030866=cortical actin cytoskeleton organization, 0035095=behavioral response to nicotine" "0016021=integral component of membrane, 0005886=plasma membrane, 0005919=pleated septate junction" "EP1631, EG:22E5.11, unnamed, CG4322, Moody receptor, 1631, Moody" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG4322 16-Dec-15 2015_12 "ENSDARG00000069225,ENSDARG00000069221,ENSDARG00000055852(LOC565718),ENSDARG00000037545(mtnr1aa),ENSDARG00000035609(mtnr1c),ENSDARG00000012057" ENSXETG00000021274(GPR84) "ENSMUSG00000056380(Gpr50),ENSMUSG00000050901(Mtnr1b)" "ENSG00000168412(MTNR1A),ENSG00000134640(MTNR1B)" "lethal,neuroanatomy defective,behavior defective,viable,chemosensitive behavior defective,partially lethal - majority die,male,recessive,some die during larval stage" "germline cell,ectopic,maternal effect,germline cell | embryonic stage" FBgn0043534 Obp57b Odorant-binding protein 57b http://flybase.net/reports/FBgn0043534.html "FBgn0050142, FBgn0063476" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG30142, 57b, obp57b, anon-AE003792.2, Obp-e, unnamed, DmelObp57b" IPR006170=Pheromone/general odorant binding protein CG30142 16-Dec-15 2015_12 DRSC21914 E -0.231921409 -0.137454033 1.047696293 1.768157677 -0.578103034 0.684722944 FBgn0039966 Rab21 Rab21 http://flybase.net/reports/FBgn0039966.html "FBan0017515, FBgn0027718, FBgn0058304" protein_coding_gene "0005525=GTP binding, 0005515=protein binding, 0003924=GTPase activity, 0036313=phosphatidylinositol 3-kinase catalytic subunit binding" "0030866=cortical actin cytoskeleton organization, 0032482=Rab protein signal transduction, 0015031=protein transport, 0016192=vesicle-mediated transport" "0055037=recycling endosome, 0005769=early endosome, 0031982=vesicle, 0045202=synapse" "CG17515, Q7PLE8, DmRab21, rab21, anon-EST:Posey237, CG40304, AAF45341" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG17515 16-Dec-15 2015_12 ENSDARG00000061751(zgc:154045) WBGene00004279(rab-21) ENSXETG00000011586(rab21) ENSMUSG00000020132(Rab21) ENSG00000080371(RAB21) macrophage DRSC20968 E 0.320072109 -0.03818283 2.295535153 0.356380935 -0.055804499 0.134998578 FBgn0259571 GG01341 http://flybase.net/reports/FBgn0259571.html gene 16-Dec-15 2015_12 visible "leg,unguis,antennal segment,arista,wing margin,macrochaeta,mesothoracic tergum,scutellum" FBgn0003673 tc tiny chaetae http://flybase.net/reports/FBgn0003673.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile,lethal" macrochaeta FBgn0025629 CG4045 http://flybase.net/reports/FBgn0025629.html protein_coding_gene 0008176=tRNA (guanine-N7-)-methyltransferase activity "0006400=tRNA modification, 0036265=RNA (guanine-N7)-methylation" 0005634=nucleus EG:22E5.4 "IPR003358=tRNA (guanine-N-7) methyltransferase, Trmb type, IPR025763=tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG4045 16-Dec-15 2015_12 YDL201W(TRM8) WBGene00012205(W02B12.10) ENSXETG00000009655(mettl1) ENSMUSG00000006732(Mettl1) ENSG00000037897(METTL1) viable FBgn0050357 CG30357 http://flybase.net/reports/FBgn0050357.html FBgn0064997 protein_coding_gene BcDNA:AT27059 "IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR011705=BTB/Kelch-associated" CG30357 16-Dec-15 2015_12 viable DRSC22472 K 0.291349218 0.429186405 0.804679199 0.544522233 0.918840742 1.545064759 FBgn0028171 l(3)S027344 lethal (3) S027344 http://flybase.net/reports/FBgn0028171.html gene 0273/44 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0261238 Alh Alhambra http://flybase.net/reports/FBgn0261238.html "FBgn0037471, FBgn0011412, FBgn0011439, FBgn0062159, FBgn0003528" protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0002168=instar larval development, 0007526=larval somatic muscle development, 0007482=haltere development, 0007591=molting cycle, chitin-based cuticle, 0045433=male courtship behavior, veined wing generated song production" 0005634=nucleus "anon-WO0118547.226, l(3)g5, l(3j8C8, l(3)j8C8, AF10, Dalf, l(3)g2, l(3)r13, sticking, ALHAMBRA, alhambra, dAF10, l(3)j8c8, stk, CG1070, l(3)84Be, l(3)j13A6" "IPR019787=Zinc finger, PHD-finger, IPR001965=Zinc finger, PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type" CG1070 16-Dec-15 2015_12 "ENSMUSG00000026743(Mllt10),ENSMUSG00000038437(Mllt6)" "ENSG00000078403(MLLT10),ENSG00000108292(MLLT6)" FBgn0045061 fs(1)127 female sterile (1) 127 http://flybase.net/reports/FBgn0045061.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "oocyte,nurse cell & nucleus" FBgn0054015 CG34015 http://flybase.net/reports/FBgn0054015.html FBgn0082900 protein_coding_gene 0003824=catalytic activity "BP1006, unnamed" "IPR001310=Histidine triad (HIT) protein, IPR011146=HIT-like domain" CG34015 16-Dec-15 2015_12 ENSDARG00000055365(si:dkey-25e12.3) WBGene00016150(hint-3) ENSXETG00000027058(hint3) ENSMUSG00000019791(Hint3) ENSG00000111911(HINT3) FBgn0082168 p160S p160S http://flybase.net/reports/FBgn0082168.html gene p160 16-Dec-15 2015_12 FBgn0025146 ms(3)A1 ms(3)A1 http://flybase.net/reports/FBgn0025146.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0031603 CG15432 http://flybase.net/reports/FBgn0031603.html protein_coding_gene 0044822=poly(A) RNA binding "0005654=nucleoplasm, 0005634=nucleus" cg15432 "IPR013865=Protein of unknown function DUF1754, eukaryotic" CG15432 16-Dec-15 2015_12 ENSDARG00000042660(fam32al) WBGene00010479(K01G5.8) ENSG00000105058(FAM32A) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC00447 I -0.716213078 2.065140499 -0.397361645 1.424338214 0.637296688 0.106080053 FBgn0002224 l(3)68Ad lethal (3) 68Ad http://flybase.net/reports/FBgn0002224.html FBgn0004711 gene "l(3)68Ad', l(3)D, Complementation group D, l(3)C117, D" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267457 CR45807 http://flybase.net/reports/FBgn0267457.html non_protein_coding_gene CR45807 16-Dec-15 2015_12 FBgn0085581 CG41255 http://flybase.net/reports/FBgn0085581.html FBan0041255 protein_coding_gene 16-Dec-15 2015_12 FBgn0003250 Rh4 Rhodopsin 4 http://flybase.net/reports/FBgn0003250.html protein_coding_gene "0008020=G-protein coupled photoreceptor activity, 0004930=G-protein coupled receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0009589=detection of UV, 0007604=phototransduction, UV, 0007601=visual perception, 0007602=phototransduction" 0016021=integral component of membrane "unnamed, Rhodopsin4, Rhodopsin, rh4, Dm Rh4, CG9668, RH4, rhodopsin 4, Rh, rhodopsin, DMELRH4, FBgn0003250" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR027430=Visual pigments (opsins) retinal binding site, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000856=Opsin RH3/RH4" CG9668 16-Dec-15 2015_12 "ENSDARG00000007553(opn4l),ENSDARG00000053929(LOC566133),ENSDARG00000022098(opn4a),ENSDARG00000051908(si:dkeyp-100d11.3)" ENSXETG00000019216(OPN4) " adult stage , pupal stage | late , larval stage " " eye

, adult head

, Bolwig's organ

, photoreceptor cell R7

" adult stage " photoreceptor cell R1..6

{ 0 ninaE- } , photoreceptor cell R1--6

, photoreceptor cell R7 | presumptive

" "viable,fertile" FBgn0051200 CG31200 http://flybase.net/reports/FBgn0051200.html FBgn0038823 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH169, CG17837" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG31200 16-Dec-15 2015_12 viable FBgn0261816 CG42758 http://flybase.net/reports/FBgn0261816.html protein_coding_gene CG13479 CG42758 16-Dec-15 2015_12 FBgn0023062 l(1)2Dk lethal (1) 2Dk http://flybase.net/reports/FBgn0023062.html gene 1200B2 16-Dec-15 2015_12 "lethal,recessive" FBgn0002185 l(3)62Bi lethal (3) 62Bi http://flybase.net/reports/FBgn0002185.html gene "l(3)dre6, dre6, rbd" 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,heat sensitive,some die during pharate adult stage" FBgn0261436 DhpD Dihydropterin deaminase http://flybase.net/reports/FBgn0261436.html "FBgn0004491, FBgn0037219, FBan0018143" protein_coding_gene "0008892=guanine deaminase activity, 0004153=dihydropterin deaminase activity, 0008270=zinc ion binding" "0006147=guanine catabolic process, 0046098=guanine metabolic process, 0006726=eye pigment biosynthetic process, 0051067=dihydropteridine metabolic process" "CG18143, unnamed" "IPR011059=Metal-dependent hydrolase, composite domain, IPR014311=Guanine deaminase, IPR006680=Amidohydrolase-related" CG18143 16-Dec-15 2015_12 ENSDARG00000002986(zgc:112282) YDL238C(GUD1) WBGene00000775(cpin-1) ENSXETG00000014370(GDA) ENSMUSG00000058624(Gda) ENSG00000119125(GDA) eye color defective pigment cell FBgn0046648 anon-38D.18 anon-38D.18 http://flybase.net/reports/FBgn0046648.html gene 38D.18 16-Dec-15 2015_12 FBgn0265156 CR44225 http://flybase.net/reports/FBgn0265156.html non_protein_coding_gene CR44225 16-Dec-15 2015_12 FBgn0065374 l(2)SH1685 lethal (2) SH1685 http://flybase.net/reports/FBgn0065374.html gene l(2)SH2 1685 16-Dec-15 2015_12 "lethal,recessive" FBgn0265740 CR44547 http://flybase.net/reports/FBgn0265740.html non_protein_coding_gene lincRNA.502 CR44547 16-Dec-15 2015_12 FBgn0266949 CR45400 http://flybase.net/reports/FBgn0266949.html non_protein_coding_gene CR45400 16-Dec-15 2015_12 FBgn0010896 l(3)06658 lethal (3) 06658 http://flybase.net/reports/FBgn0010896.html gene 16-Dec-15 2015_12 lethal FBgn0030984 tgy twiggy http://flybase.net/reports/FBgn0030984.html "FBtr0074702, FBpp0074471" protein_coding_gene "0016757=transferase activity, transferring glycosyl groups, 0008378=galactosyltransferase activity" "0035220=wing disc development, 0007440=foregut morphogenesis" 0016020=membrane "CG7440, Tgy, dC1GalT5" IPR003378=Fringe-like CG7440 16-Dec-15 2015_12 viable FBgn0053428 5SrRNA:CR33428 5SrRNA:CR33428 http://flybase.net/reports/FBgn0053428.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33428 CR33428 16-Dec-15 2015_12 FBgn0266363 CG45011 http://flybase.net/reports/FBgn0266363.html protein_coding_gene IPR002350=Kazal domain CG45011 16-Dec-15 2015_12 FBgn0052441 CG32441 http://flybase.net/reports/FBgn0052441.html FBgn0037103 protein_coding_gene CG7783 IPR029615=ER membrane protein complex subunit 10 CG32441 16-Dec-15 2015_12 ENSDARG00000054793(zgc:171980) WBGene00012829(Y43F8C.7) ENSXETG00000024985(TNeu053m17.1) ENSMUSG00000008140(2310044H10Rik) ENSG00000161671(C19orf63) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0028191 l(3)S022930 lethal (3) S022930 http://flybase.net/reports/FBgn0028191.html gene 0229/30 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0065617 l(2)SH0817 lethal (2) SH0817 http://flybase.net/reports/FBgn0065617.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043490 en::onecut en::onecut http://flybase.net/reports/FBgn0043490.html engineered_fusion_gene 16-Dec-15 2015_12 "eye,eye photoreceptor cell,retina,optic lobe" FBgn0003698 thiv thickened veins http://flybase.net/reports/FBgn0003698.html gene thi 16-Dec-15 2015_12 "visible,recessive,cold sensitive" FBgn0038735 CG4662 http://flybase.net/reports/FBgn0038735.html protein_coding_gene 0005509=calcium ion binding "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG4662 16-Dec-15 2015_12 ENSDARG00000009939(zgc:113196) WBGene00008345(C56A3.6) ENSXETG00000014500(EFHA2) ENSMUSG00000039478(Efha2) ENSG00000155970(EFHA2) "viable,fertile" FBgn0005352 su(Cy)r "suppressor of Curly, recessive" http://flybase.net/reports/FBgn0005352.html gene "suppressor of Curly, su(Cy)" 16-Dec-15 2015_12 FBgn0016692 Pas Partial sevenless http://flybase.net/reports/FBgn0016692.html gene "0007422=peripheral nervous system development, 0007417=central nervous system development, 0042051=compound eye photoreceptor development" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval central nervous system,rhabdomere" FBgn0045973 PdL72A3 PdL72A3 http://flybase.net/reports/FBgn0045973.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0014090 anon-31Ea anonymous at 31E-a http://flybase.net/reports/FBgn0014090.html gene 16-Dec-15 2015_12 FBgn0267136 CR45576 http://flybase.net/reports/FBgn0267136.html non_protein_coding_gene lincRNA.738 CR45576 16-Dec-15 2015_12 FBgn0261592 RpS6 Ribosomal protein S6 http://flybase.net/reports/FBgn0261592.html "FBgn0004922, FBgn0004371, FBgn0004388, FBgn0065997, FBgn0005276, FBgn0004405, FBgn0002584, FBgn0002585" protein_coding_gene 0003735=structural constituent of ribosome "0042274=ribosomal small subunit biogenesis, 0007052=mitotic spindle organization, 0006364=rRNA processing, 0006412=translation, 0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0006955=immune response" "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "rpS6, hemocytes enlarged, Rp S6, l(1)hen, M(1)7C, S6, (Rp)S6, DS6, S6 ribosomal protein, air8, air[8], Minute, l(1)air8, anon-WO02059370.61, rps6, lethal(1)aberrant immune response[8], Minute (1) 7BC, pp30, ribosomal protein S6, CG10944, RPS6, Rps6, M(1)7BC, lethal-(1)-haemocytes enlarged, hen, l(1)air[8], lethal-aberrant-immune-response-8" "IPR014401=Ribosomal protein S6, eukaryotic, IPR001377=Ribosomal protein S6e, IPR018282=Ribosomal protein S6e, conserved site" CG10944 16-Dec-15 2015_12 ENSDARG00000019778(zgc:92237) "YPL090C(RPS6A),YBR181C(RPS6B)" WBGene00004475(rps-6) ENSXETG00000023100(rps6-2) "ENSMUSG00000028495(Rps6),ENSMUSG00000056772(Gm16409),ENSMUSG00000063875(Rps6-ps1),ENSMUSG00000075581(Rps6-ps2)" ENSG00000137154(RPS6) embryonic stage -- adult stage DRSC18712 EK -1.315846862 -1.054685785 0.72029246 -3.624350145 1.87134093 4.108212097 FBgn0014896 anon-10Ac anon-10Ac http://flybase.net/reports/FBgn0014896.html gene unnamed 16-Dec-15 2015_12 FBgn0260311 GSd477 http://flybase.net/reports/FBgn0260311.html gene 16-Dec-15 2015_12 lethal FBgn0028139 l(3)S048301a lethal (3) S048301a http://flybase.net/reports/FBgn0028139.html gene "0483/01, l(3)S048301" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067372 l(2)NC14 lethal (2) NC14 http://flybase.net/reports/FBgn0067372.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265878 CR44667 http://flybase.net/reports/FBgn0265878.html non_protein_coding_gene lincRNA.367 CR44667 16-Dec-15 2015_12 FBgn0063384 snoRNA:U29:54Eb snoRNA:U29:54Eb http://flybase.net/reports/FBgn0063384.html snoRNA_gene "U29snoRNA, CR32890, DmSnR71a" CR32890 16-Dec-15 2015_12 FBgn0015029 CU61 Cible d'Ubx 61 http://flybase.net/reports/FBgn0015029.html gene "Cu61, 61" 16-Dec-15 2015_12 FBgn0033547 CG12935 http://flybase.net/reports/FBgn0033547.html protein_coding_gene 0007399=nervous system development IPR026100=Transmembrane protein 223 CG12935 16-Dec-15 2015_12 ENSDARG00000069494(zgc:101024) ENSMUSG00000075043(Tmem223) ENSG00000168569(TMEM223) viable DRSC07025 K -0.768590933 0.27342169 0.519999025 -0.233746873 1.771573807 1.230042146 FBgn0066319 24D1 24D1 http://flybase.net/reports/FBgn0066319.html gene 16-Dec-15 2015_12 FBgn0023492 Mst78D Mst78D http://flybase.net/reports/FBgn0023492.html gene 16-Dec-15 2015_12 FBgn0259850 Su(Ste):CR42419 Su(Ste):CR42419 http://flybase.net/reports/FBgn0259850.html non_protein_coding_gene CR42419 CR42419 16-Dec-15 2015_12 FBgn0261974 snoRNA:Or-CD9b http://flybase.net/reports/FBgn0261974.html "FBgn0082917, FBgn0083059" snoRNA_gene 0005654=nucleoplasm "snmRNA:60Cb, CR34567, snm60, Dmsnm60b, CR42805, DmOrC/D_9b, orphan CD9b, DmOr_cd9b snoRNA, CR34101, snoRNA:Or-cd9b, Snm60b, small non-messenger RNA 60Cb" CR42805 16-Dec-15 2015_12 FBgn0034827 Klp59D Kinesin-like protein at 59D http://flybase.net/reports/FBgn0034827.html protein_coding_gene "0003777=microtubule motor activity, 0008017=microtubule binding, 0003774=motor activity, 0005524=ATP binding" 0007018=microtubule-based movement 0005871=kinesin complex "Klp59D, CG12192, KLP59D, Kinesin-like protein at 59D, DmKlp59D, KIF2A/B/C" "IPR001752=Kinesin motor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027640=Kinesin-like protein" CG12192 16-Dec-15 2015_12 WBGene00002219(klp-7) viable FBgn0082372 EP2182 EP2182 http://flybase.net/reports/FBgn0082372.html gene 16-Dec-15 2015_12 "germline cell,male,embryonic/larval salivary gland" FBgn0265983 CR44762 http://flybase.net/reports/FBgn0265983.html non_protein_coding_gene CR44762 16-Dec-15 2015_12 FBgn0028999 nerfin-1 nervous fingers 1 http://flybase.net/reports/FBgn0028999.html FBgn0035177 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "0007411=axon guidance, 0048666=neuron development, 0048813=dendrite morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0048663=neuron fate commitment" 0005634=nucleus "Nerfin, nerfin-1, CG13906, Nervous finger-1, nerfin, Nerfin-1, Nervous fingers 1, nerfin 1" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG13906 16-Dec-15 2015_12 "ENSG00000168348(INSM2),ENSG00000173404(INSM1)" "viable,lethal - all die before end of pupal stage,some die during pupal stage" "longitudinal connective,anterior commissure,posterior commissure,pCC neuron,intermediate longitudinal fascicle,lateral longitudinal fascicle,medial longitudinal fascicle" FBgn0266934 CR45385 http://flybase.net/reports/FBgn0266934.html pseudogene_attribute CR45385 16-Dec-15 2015_12 FBgn0002240 l(3)68Cb lethal (3) 68Cb http://flybase.net/reports/FBgn0002240.html gene l(3)C605 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal" FBgn0262761 Mst77Y-12 Male-specific transcript 77Y 12 http://flybase.net/reports/FBgn0262761.html nuclear_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin 16-Dec-15 2015_12 FBgn0038001 CG17404 http://flybase.net/reports/FBgn0038001.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP149 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG17404 16-Dec-15 2015_12 viable DRSC15234 E 0.076363876 0.484088478 1.428018162 1.882274061 0.161500743 -0.068919954 FBgn0028638 ifm(2)RU4 indirect flight muscle (2) RU4 http://flybase.net/reports/FBgn0028638.html gene 0007517=muscle organ development 0005703=polytene chromosome puff 16-Dec-15 2015_12 "visible,recessive,flight defective,fertile,viable" "wing,dorsal medial muscle,dorsal medial muscle & myofibril" FBgn0261732 EC2374 http://flybase.net/reports/FBgn0261732.html gene 16-Dec-15 2015_12 "some die during embryonic stage,lethal - all die before end of embryonic stage" FBgn0052945 CG32945 http://flybase.net/reports/FBgn0052945.html protein_coding_gene CG32945 16-Dec-15 2015_12 viable FBgn0262064 EG165 http://flybase.net/reports/FBgn0262064.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065813 l(2)SH0382 lethal (2) SH0382 http://flybase.net/reports/FBgn0065813.html gene l(2)SH2 0382 16-Dec-15 2015_12 "lethal,recessive" FBgn0261258 rgn regeneration http://flybase.net/reports/FBgn0261258.html "FBgn0010719, FBgn0027542" protein_coding_gene 0030246=carbohydrate binding 0042246=tissue regeneration "l(3)00534, lethal (3) 00534, CG6014, BcDNA:GH11973" "IPR016186=C-type lectin-like, IPR016187=C-type lectin fold, IPR001304=C-type lectin" CG6014 16-Dec-15 2015_12 FBgn0025383 CG14780 http://flybase.net/reports/FBgn0025383.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP95, EG:80H7.3" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG14780 16-Dec-15 2015_12 viable FBgn0037610 CG8043 http://flybase.net/reports/FBgn0037610.html protein_coding_gene Iba57 "IPR006222=Glycine cleavage T-protein-like, N-terminal, IPR013977=Glycine cleavage T-protein, C-terminal barrel domain, IPR017703=YgfZ/GcvT conserved site" CG8043 16-Dec-15 2015_12 ENSDARG00000063446(LOC100330979) YJR122W(IBA57) WBGene00009563(F39H2.3) ENSXETG00000006176(C1orf69) ENSMUSG00000049287(A230051G13Rik) ENSG00000181873(IBA57) "partially lethal - majority die,some die during pupal stage,locomotor rhythm defective" FBgn0033279 CG2291 http://flybase.net/reports/FBgn0033279.html FBgn0063327 protein_coding_gene BcDNA:AT16234 CG2291 16-Dec-15 2015_12 viable FBgn0015359 CG2034 http://flybase.net/reports/FBgn0015359.html protein_coding_gene anon-i1 CG2034 16-Dec-15 2015_12 viable embryonic/larval hemocyte | third instar larval stage FBgn0034909 CG4797 http://flybase.net/reports/FBgn0034909.html protein_coding_gene 0005355=glucose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane Sugar transporter-like "IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG4797 16-Dec-15 2015_12 YDR387C() "viable,fertile,partially lethal - majority die,visible" mesothoracic tergum FBgn0036474 Or71a Odorant receptor 71a http://flybase.net/reports/FBgn0036474.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0032590=dendrite membrane, 0016021=integral component of membrane" "OR71a, 71a, CG17871, 71B.1, Or71c, or71a, DOR14" "IPR004117=Olfactory receptor, Drosophila" CG17871 16-Dec-15 2015_12 FBgn0019770 l(1)48B lethal (1) 48B http://flybase.net/reports/FBgn0019770.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0019638 ApII Apurinic/apyrimidinic endonuclease II http://flybase.net/reports/FBgn0019638.html gene 0003906=DNA-(apurinic or apyrimidinic site) lyase activity 0006281=DNA repair unnamed 16-Dec-15 2015_12 FBgn0002647 mapP midgut amylase pattern PMG http://flybase.net/reports/FBgn0002647.html gene "map, map-PMG" 16-Dec-15 2015_12 FBgn0034243 Ns2 Nucleostemin ortholog (H. sapiens) 2 http://flybase.net/reports/FBgn0034243.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0042254=ribosome biogenesis, 0001745=compound eye morphogenesis, 0040018=positive regulation of multicellular organism growth, 0006909=phagocytosis" "0005654=nucleoplasm, 0005730=nucleolus, 0005634=nucleus" "nucleostemin 2, ns2, dmNS2, CG6501, Ngp1, NS2, Ngp, Nucleostemin 2" "IPR006073=GTP binding domain, IPR012971=Nucleolar GTP-binding protein 2, N-terminal domain, IPR024929=Nucleolar GTP-binding protein 2, IPR023179=GTP-binding protein, orthogonal bundle domain, IPR030378=Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6501 16-Dec-15 2015_12 "ENSDARG00000053225(gnl2),ENSDARG00000053378" YNR053C(NOG2) WBGene00003596(ngp-1) ENSXETG00000002161(gnl2) ENSMUSG00000028869(Gnl2) ENSG00000134697(GNL2) "cell lethalcell lethal,recessive,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,visible,long lived" "wing disc,somatic clone,eye" DRSC06993 E -1.237858552 0.866919167 2.358023133 -0.671870781 -0.299468794 1.283393864 FBgn0002645 Map205 Microtubule-associated protein 205 http://flybase.net/reports/FBgn0002645.html protein_coding_gene 0008017=microtubule binding "0000278=mitotic cell cycle, 0007017=microtubule-based process, 0051297=centrosome organization" "0005881=cytoplasmic microtubule, 0030496=midbody, 0005875=microtubule associated complex, 0005819=spindle, 0005876=spindle microtubule" "MAP205, 205kDa MAP, 205-kDa MAP, MAP4, 205kD MAP, 205K MAP, CG1483, map205" CG1483 16-Dec-15 2015_12 "viable,fertile" FBgn0002335 l(3)87Bc lethal (3) 87Bc http://flybase.net/reports/FBgn0002335.html gene "l(3)ck15, ck15" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0011892 tRNA:K2:42Ea transfer RNA:lys2:42Ea http://flybase.net/reports/FBgn0011892.html "FBgn0003796, FBgn0011886, FBgn0011900, FBgn0050300, FBgn0060180" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K:CTT:AE002778-d, chr2R.trna91-LysCTT, tRNA:K4, CR30300, AE002778.trna4-LysCTT, tRNAlys, tRNA:lys2:42Ea, tRNA[Lys][[2]], tRNA:K2" CR30300 16-Dec-15 2015_12 FBgn0026395 Or23a Odorant receptor 23a http://flybase.net/reports/FBgn0026395.html protein_coding_gene "0004984=olfactory receptor activity, 0004888=transmembrane signaling receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0030425=dendrite, 0016021=integral component of membrane, 0043025=neuronal cell body, 0032590=dendrite membrane" "dor64, Dor64, CG9880, Odorant receptor 64, AN5, 23a, DOR23A.1, Or64, or23a, 23A.1, DOR64, AN5, Or23A.1, Olfactory receptor 23A.1, DOR64" "IPR004117=Olfactory receptor, Drosophila" CG9880 16-Dec-15 2015_12 adult stage " sensory neuron &&of maxillary palpus

, sensory neuron &&of antennal segment 3

" FBgn0036496 CG7804 http://flybase.net/reports/FBgn0036496.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" cg7804 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG7804 16-Dec-15 2015_12 "ENSDARG00000040031(tardbp),ENSDARG00000004452(tardbpl)" WBGene00006514(tdp-1) ENSXETG00000006317(tardbp) ENSMUSG00000041459(Tardbp) ENSG00000120948(TARDBP) "viable,partially lethal - majority die,some die during pupal stage" FBgn0046636 anon-38D.9 anon-38D.9 http://flybase.net/reports/FBgn0046636.html gene 38D.9 16-Dec-15 2015_12 FBgn0017562 Oef2 oe1 binding factor 2 http://flybase.net/reports/FBgn0017562.html gene 0003677=DNA binding 0005634=nucleus OEF2 16-Dec-15 2015_12 FBgn0010564 l(2)04012a lethal (2) 04012a http://flybase.net/reports/FBgn0010564.html gene "l(2)04012, 4012" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001625 l(1)dn2 lethal (1) discs normal 2 http://flybase.net/reports/FBgn0001625.html gene l(1)d.norm.-2 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0039212 Syx18 Syntaxin 18 http://flybase.net/reports/FBgn0039212.html protein_coding_gene "0005484=SNAP receptor activity, 0000149=SNARE binding" "0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0007528=neuromuscular junction development, 0007274=neuromuscular synaptic transmission" "0031594=neuromuscular junction, 0005886=plasma membrane, 0005938=cell cortex, 0031201=SNARE complex" "syntaxin, Gtaxin, DmSyx18, gtx, CG13626, Syx, Dm Ufe1, Ufe1/Syntaxin 18, Syntaxin" "IPR000727=Target SNARE coiled-coil homology domain, IPR019529=SNARE-complex protein Syntaxin-18, N-terminal" CG13626 16-Dec-15 2015_12 YOR075W(UFE1) WBGene00020425(syx-18) ENSXETG00000016051(STX18) ENSMUSG00000029125(Stx18) ENSG00000168818(STX18) "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,neurophysiology defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,visible,partially lethal - majority die,some die during pupal stage" "NMJ bouton,endomembrane system & embryonic/larval somatic muscle,embryonic/larval somatic muscle,subsynaptic reticulum,neuromuscular junction,embryonic/larval neuromuscular junction,subsynaptic reticulum | ectopicC57,mesothoracic tergum" DRSC14628 I 4.24921079 0.79566397 1.14461768 -0.997504847 -0.23413268 -0.447899628 FBgn0000779 fs(1)A1459 female sterile (1) A1459 http://flybase.net/reports/FBgn0000779.html gene 0048477=oogenesis "fs(1)M23, fs(1)K499, fs(1)1459, fs(1)M2" 16-Dec-15 2015_12 "lethal,maternal effect,female sterile,recessive,heat sensitive,non-rescuable maternal effect" "gastrula embryo,maternal effect,blastoderm embryo" FBgn0028475 Hrd3 http://flybase.net/reports/FBgn0028475.html protein_coding_gene 0005886=plasma membrane "HRD3, BcDNA:LD23587, CG10221, Hrd3" "IPR006597=Sel1-like repeat, IPR011990=Tetratricopeptide-like helical domain" CG10221 16-Dec-15 2015_12 ENSDARG00000004581(si:dkey-177p2.3) YLR207W(HRD3) WBGene00004759(sel-1) ENSXETG00000010038(SEL1L) ENSMUSG00000020964(Sel1l) ENSG00000071537(SEL1L) "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0030099 CG12056 http://flybase.net/reports/FBgn0030099.html protein_coding_gene IPR001199=Cytochrome b5-like heme/steroid binding domain CG12056 16-Dec-15 2015_12 ENSDARG00000061006(si:ch211-117m20.9) WBGene00006478(tag-131) ENSXETG00000018225(TNeu100j22.1) ENSMUSG00000057778(Cyb5d2) ENSG00000167740(CYB5D2) FBgn0000490 dpp decapentaplegic http://flybase.net/reports/FBgn0000490.html FBgn0010065 protein_coding_gene "0008201=heparin binding, 0005518=collagen binding, 0016015=morphogen activity, 0005160=transforming growth factor beta receptor binding, 0005515=protein binding, 0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0008083=growth factor activity" "0030721=spectrosome organization, 0009948=anterior/posterior axis specification, 0001745=compound eye morphogenesis, 0007304=chorion-containing eggshell formation, 0035168=larval lymph gland hemocyte differentiation, 0035309=wing and notum subfield formation, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0060323=head morphogenesis, 0007448=anterior/posterior pattern specification, imaginal disc, 0045595=regulation of cell differentiation, 0001709=cell fate determination, 0045570=regulation of imaginal disc growth, 0007473=wing disc proximal/distal pattern formation, 0042127=regulation of cell proliferation, 0007455=eye-antennal disc morphogenesis, 0007447=imaginal disc pattern formation, 0045476=nurse cell apoptotic process, 0007281=germ cell development, 0035214=eye-antennal disc development, 0061353=BMP signaling pathway involved in Malpighian tubule cell chemotaxis, 0045705=negative regulation of salivary gland boundary specification, 0035217=labial disc development, 0048066=developmental pigmentation, 0035156=fusion cell fate specification, 0007440=foregut morphogenesis, 0030509=BMP signaling pathway, 0007446=imaginal disc growth, 0048477=oogenesis, 0019827=stem cell maintenance, 0048542=lymph gland development, 0008285=negative regulation of cell proliferation, 0007313=maternal specification of dorsal/ventral axis, oocyte, soma encoded, 0007444=imaginal disc development, 0007423=sensory organ development, 0048100=wing disc anterior/posterior pattern formation, 0007352=zygotic specification of dorsal/ventral axis, 0036099=female germ-line stem cell maintenance, 0007443=Malpighian tubule morphogenesis, 0007425=epithelial cell fate determination, open tracheal system, 0001715=ectodermal cell fate specification, 0008354=germ cell migration, 0001708=cell fate specification, 0061320=pericardial nephrocyte differentiation, 0007398=ectoderm development, 0010002=cardioblast differentiation, 0007450=dorsal/ventral pattern formation, imaginal disc, 0007424=open tracheal system development, 0007427=epithelial cell migration, open tracheal system, 0007516=hemocyte development, 0007442=hindgut morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0030707=ovarian follicle cell development, 0007354=zygotic determination of anterior/posterior axis, embryo, 0007391=dorsal closure, 0007479=leg disc proximal/distal pattern formation, 0035263=genital disc sexually dimorphic development, 0007498=mesoderm development, 0030718=germ-line stem cell maintenance, 0046620=regulation of organ growth, 0042078=germ-line stem cell division, 0017145=stem cell division, 0046843=dorsal appendage formation, 0035158=regulation of tube diameter, open tracheal system, 0007507=heart development, 0035222=wing disc pattern formation, 0010629=negative regulation of gene expression, 0035224=genital disc anterior/posterior pattern formation, 0035147=branch fusion, open tracheal system, 0007393=dorsal closure, leading edge cell fate determination, 0007179=transforming growth factor beta receptor signaling pathway, 0007378=amnioserosa formation, 0061327=anterior Malpighian tubule development, 0048636=positive regulation of muscle organ development, 0009950=dorsal/ventral axis specification, 0035215=genital disc development, 0008586=imaginal disc-derived wing vein morphogenesis, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0007474=imaginal disc-derived wing vein specification" "0035230=cytoneme, 0005768=endosome, 0005615=extracellular space, 0005622=intracellular" "DPP-C, l(2)10638, shv, Decapentaplegic, Dm-DPP, DPP, shortvein, blk, TGF-beta, unnamed, BMP, TGFbeta, bone morphogenic protein, Tg, CG9885, bone morphogenetic protein, Tegula, l(2)22Fa, M(2)LS1, M(2)23AB, ho, TGF-b, blink, Hin-d, Dpp, l(2)k17036, Haplo-insufficient, heldout, Decapentaplegic/Bone Morphogenetic Protein" "IPR017948=Transforming growth factor beta, conserved site, IPR001111=Transforming growth factor-beta, N-terminal, IPR002405=Inhibin, alpha subunit, IPR001839=Transforming growth factor-beta, C-terminal, IPR029034=Cystine-knot cytokine, IPR015615=Transforming growth factor-beta-related" CG9885 16-Dec-15 2015_12 "ENSDARG00000041430(bmp2b),ENSDARG00000013409(bmp2a),ENSDARG00000019995(bmp4)" WBGene00006570(tig-2) "ENSXETG00000005519(bmp2),ENSXETG00000008620(bmp4)" "ENSMUSG00000027358(Bmp2),ENSMUSG00000021835(Bmp4)" "ENSG00000125845(BMP2),ENSG00000125378(BMP4)" " larval stage | third instar , embryonic stage | cellular blastoderm , embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage , embryonic stage | mid-late , prepupal stage , embryonic stage | stage 11-17 , larval stage | first instar , pupal stage | >=18-20 hr , embryonic stage | stage 11 , prepupal stage | 6-9 hr , embryonic stage | mid &late , embryonic stage | stage 12 , embryonic stage | stage 13-16 , larval stage " " ventral thoracic disc | restricted

, dorsal ectoderm anlage

, dorsal mesothoracic disc | restricted

, male genital disc | restricted

, embryonic/larval esophagus

, embryonic brain

, visceral mesoderm &&of parasegment 8--12

, ventral mesothoracic disc | resticted

, parasegment 7

{ + abd-AM1 } , midgut constriction 3

, female genital disc | restricted

, midgut constriction 2

, imaginal disc primordium

, wing vein | primordium

, eye-antennal disc | restricted

, midgut

{ v dpps21/dpps4 } , parasegment 7 visceral mesoderm

{ - Ubx1 } , thoracic segment

, dorsal mesothoracic disc | restriced

, procephalic segment

, foregut

{ + abd-AM1 } , larval labral segment sense organ

, visceral mesoderm &&of parasegment 7

, larval brain | restricted

, gastric caecum

, dorsal mesothoracic disc | anterior/posterior compartment boundary

, embryonic/larval hindgut

, embryonic/larval foregut

{ - dpps21/dpps4 } , visceral mesoderm &&of parasegment 7--12

, embryonic/larval pharynx

" " embryonic stage | stage 14-17 , larval stage | third instar , embryonic stage | mid-late , embryonic stage | stage 16-17 , embryonic stage | stage 12 " " midgut constriction 2

, morphogenetic furrow

, parasegment 3,8..12 visceral mesoderm

{ + Ubxhs.PU, Ubx-, abd-A- } , parasegment 7 &&of endoderm

, visceral mesoderm &&of parasegment 2--12

, parasegment 7 &&of visceral mesoderm

, visceral mesoderm &&of parasegment 7

, eye disc | ubiquitous

, parasegment 6..7 visceral mesoderm

{ + Ubxhs.PU } , dorsal mesothoracic disc | ubiquitous

, parasegment 3,6..7 visceral mesoderm

{ - Ubx6.28 } , parasegment 3..7 visceral mesoderm

{ + abd-AMX1 } , parasegment 3,6..12 visceral mesoderm

{ $ Ubx-, abd-A- } , ventral thoracic disc | ubiquitous

, dorsal mesothoracic disc | anterior posterior gradient

" "visible,recessive,lethal,some die during embryonic stage,dominant,short lived,RU486 conditional,circadian rhythm defective,heat sensitive,viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,wild-type,increased cell death,somatic clone,partially lethal - majority die,size defective,reduced,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,female fertile,increased cell number,immune response defective,conditional,homeotic,tumorigenic,female sterile,hyperplasia,decreased cell number" ",embryonic/first instar larval cuticle,wing vein,wing,unguis,leg,eye,antenna,medulla neuropil,ommatidium,embryonic dorsal epidermis,cephalopharyngeal skeleton,filzkorper,embryonic thorax,embryonic head,head,antennal disc,ventral thoracic disc,spermatogonium,ventral nerve cord commissure,longitudinal connective,frons,retina,morphogenetic furrow,eye-antennal disc,male genitalia,penis,gonopod thorn bristle,gonopod long bristle,dorsal appendage,mesothoracic extracoxal depressor muscle 66,submarginal cell,1st posterior cell,cephalic furrow,amnioserosa,vibrissae,maxillary palpus,rostral membrane,gena,adult head,sternite,clasper,female gonopod,follicle cell,tergite,embryonic epidermis,dil cell,crossvein,wing cell,anterior crossvein,dpphr4,germarium,female germline stem cell,embryonic abdomen,abdominal segment,chorion,egg operculum,egg,micropyle,embryonic head epidermis,embryonic optic lobe primordium,wing disc,cardial valve,alula,female analia,male terminalia,capitellum,tibia,femur,sex comb,arista,fourth segment of antenna,fifth segment of antenna,taste bristle,genital disc,imaginal disc,egg chamber,macrochaeta,microchaeta,scutum,anal plate,lateral plate,head capsule,haltere,crystal cell,posterior crossvein,embryonic gnathal segment,cardiogenic mesoderm,embryonic/larval lymph gland,cardioblast,embryonic optic lobe,mitotic domain 1,mitotic domain 3,mitotic domain 5,embryonic hindgut,embryonic large intestine,extended germ band embryo,cuticle,Bolwig organ,corpus cardiacum primordium,embryo,larval head,gastric caecum,embryonic/larval midgut,scutellar bristle,third segment of antenna,dorsal hair,tegula,supraalar bristle,secondary pigment cell,tertiary pigment cell,interommatidial bristle,wing margin bristle,embryonic anal pad,maxillary palp sense organ,antennal sense organ,gastric caecum primordium,midgut constriction,embryonic dorsal pouch primordium,male analia,pseudotrachea,dpphr56,germline cell,hub cell,genital disc primordium,labellum,scutellum,embryonic/larval cuticle,embryonic/larval foregut,embryonic/larval pericardial cell,mesoderm,embryonic/larval heart,hemocyte,plasmatocyte,lamellocyte,A1-7 dorsal oblique muscle 1,haltere disc,sensillum campaniformium of dorsal radius,sensillum campaniformium of proximal ventral radius,prescutum,vulva,dorsal double row,ventral double row,dorsal triple row,medial triple row,ventral triple row,terminalia,tracheocyte,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,eye disc,wing hair,germarium cap cell,stem cell fusome,male germline stem cell,primary spermatocyte,tracheal branch primordium,embryonic/larval tracheal system,germline cyst,oocyte,interfollicle cell,presumptive embryonic/larval tracheal system,embryonic/larval dorsal branch,embryonic anterior Malpighian tubule,zen.Kr.PF,twi.PGa,fat body/gonad primordium,epidermis,spermatocyte,primary gonial cell,spermatid,testis,wing disc |,embryonic/larval visceral branch,tracheal tip cell |,btl.PS,spiracular chamber,midgut,GMR.PF,subretinal glial cell,dorsal mesothoracic disc primordium,prothoracic leg,mesothoracic leg,metathoracic leg,dpp.blk1,visual primordium,labral segment,ovary,female germline cell,adult midgut precursor cell" DRSC00118 I 0.328255955 2.378687749 -0.31386119 0.123479339 -0.259937839 -0.103012015 FBgn0020182 Ddc::ftz Ddc::ftz http://flybase.net/reports/FBgn0020182.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0019639 ApI Apurinic/apyrimidinic endonuclease I http://flybase.net/reports/FBgn0019639.html gene 0003906=DNA-(apurinic or apyrimidinic site) lyase activity 0006281=DNA repair unnamed 16-Dec-15 2015_12 FBgn0069069 20-51 20-51 http://flybase.net/reports/FBgn0069069.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" FBgn0266500 s-200 http://flybase.net/reports/FBgn0266500.html gene 16-Dec-15 2015_12 FBgn0040026 CG17653 http://flybase.net/reports/FBgn0040026.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032104 aust australin http://flybase.net/reports/FBgn0032104.html protein_coding_gene 0003677=DNA binding "0007112=male meiosis cytokinesis, 0007065=male meiosis sister chromatid cohesion, 0007060=male meiosis chromosome segregation" "0032133=chromosome passenger complex, 1990385=meiotic spindle midzone, 0000776=kinetochore" CG17009 IPR018867=Cell division protein borealin CG17009 16-Dec-15 2015_12 "viable,visible,cytokinesis defective,male,meiotic cell cycle defective,male sterile" mesothoracic tergum FBgn0023178 Pdf Pigment-dispersing factor http://flybase.net/reports/FBgn0023178.html "FBgn0044602, FBgn0044606, FBgn0047045" protein_coding_gene "0005179=hormone activity, 0005184=neuropeptide hormone activity, 0005102=receptor binding" "0010841=positive regulation of circadian sleep/wake cycle, wakefulness, 0043153=entrainment of circadian clock by photoperiod, 0007617=mating behavior, 0007218=neuropeptide signaling pathway, 0042332=gravitaxis, 0042749=regulation of circadian sleep/wake cycle, 0042745=circadian sleep/wake cycle, 0007623=circadian rhythm, 0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0008062=eclosion rhythm, 0045475=locomotor rhythm" 0005615=extracellular space "PIGMENT-DISPERSING FACTOR, PDF, Drm-PDH, PAP, CG6496, Drm-PDF, anon-WO0140519.261, pigment dispersing factor, BcDNA:RH08487, pdf, pigment dispersion factor, Pigment-dispersing factor, Drm-pdf, PDH, pigment-dispersing hormone, Pigment dispersing factor, pigment-dispersing factor, anon-WO0140519.3, Pigment Dispersing Factor, cPDH, PIGMENT DISPERSING FACTOR, pigment dispersing hormone, PDF-associated peptide, Pigment-dispersing hormone-like peptide, Pigment-dispersing hormone, Pigment-Dispersing Factor" IPR009396=Pigment-dispersing hormone CG6496 16-Dec-15 2015_12 adult stage adult head

larval stage | third instar " cell body &&of larval lateral neuron

, larval lateral neuron

" "locomotor rhythm defective,mating rhythm defective,mating defective,recessive,circadian rhythm defective,photoperiod response variant,behavior defective,gravitaxis defective,circadian behavior defective,body color defective,partially lethal - majority die,some die during pupal stage" "LNv neuron,LNd neuron,mesothoracic tergum" DRSC16786 K 0.958538982 -0.114084029 -0.66076399 -0.057835684 1.864466002 0.203631205 FBgn0028622 qsm quasimodo http://flybase.net/reports/FBgn0028622.html "FBgn0034522, FBgn0040727, FBgn0043360, FBgn0044465" protein_coding_gene "0045475=locomotor rhythm, 0000902=cell morphogenesis" "unnamed, QUASIMODO, EP2587, CG13433, CG13432, EP2356, l(2)k009920, Quasimodo, QSM, lethal (2) 05510, L(2)05510, l(2)05510" IPR001507=Zona pellucida domain CG13432 16-Dec-15 2015_12 "lethal,recessive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective,neuroanatomy defective" "adult thorax,ommatidium,eye,embryonic/larval salivary gland,dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell,intersegmental nerve,anterior fascicle & synapse | supernumerary,embryonic/larval central nervous system,wing" DRSC06393 I -0.998993484 -1.853041451 -0.784492151 -0.266703295 0.316416831 0.206354582 FBgn0052405 Cpr65Av Cuticular protein 65Av http://flybase.net/reports/FBgn0052405.html "FBgn0035684, FBgn0064890" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr65Av, CG32405, BcDNA:RE31218, CG10461" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG32405 16-Dec-15 2015_12 viable FBgn0010774 Ref1 RNA and export factor binding protein 1 http://flybase.net/reports/FBgn0010774.html FBgn0027857 protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003713=transcription coactivator activity, 0003676=nucleic acid binding" "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005654=nucleoplasm, 0071013=catalytic step 2 spliceosome, 0031965=nuclear membrane" "CG1101, ALY, DmREF1, ref1, cg1101, REF1, l(3)02267, aly, BcDNA:LD24793, Aly, dmREF1" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR025715=Friend of PRMT1 duplication" CG1101 16-Dec-15 2015_12 YDR381W(YRA1) "WBGene00000121(aly-2),WBGene00000122(aly-3),WBGene00000120(aly-1)" ENSXETG00000005391(thoc4) "ENSMUSG00000025134(Thoc4),ENSMUSG00000060244(Refbp2)" "ENSG00000183684(THOC4),ENSG00000219039"

"lethal,recessive,viable,visible,planar polarity defective,female semi-sterile,female fertile" "trichogen cell,supernumerary" DRSC22387 IE 2.800958662 1.499724054 7.369790215 4.863691565 0.035585267 -0.082481817 FBgn0259830 ifm(2)RS14 indirect flight muscle (2) RS14 http://flybase.net/reports/FBgn0259830.html gene 0007527=adult somatic muscle development 16-Dec-15 2015_12 viable indirect flight muscle FBgn0001711 l(1)ESHS32 lethal (1) ESHS32 http://flybase.net/reports/FBgn0001711.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0064193 arbl arborless http://flybase.net/reports/FBgn0064193.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 FBgn0085486 CG34457 http://flybase.net/reports/FBgn0085486.html "FBgn0034147, FBan0005197" protein_coding_gene "SP118, CG5197" CG34457 16-Dec-15 2015_12 ENSDARG00000018281(zgc:110373) ENSXETG00000012978(C15orf26) ENSMUSG00000011154(1700026D08Rik) ENSG00000156206(C15orf26) FBgn0259839 Su(Ste):CR42408 Su(Ste):CR42408 http://flybase.net/reports/FBgn0259839.html non_protein_coding_gene CR42408 CR42408 16-Dec-15 2015_12 FBgn0033354 FANCI Fanconi anemia complementation group I homologue http://flybase.net/reports/FBgn0033354.html protein_coding_gene "0006281=DNA repair, 0007095=mitotic G2 DNA damage checkpoint" "CG13745, fanci" "IPR016024=Armadillo-type fold, IPR029308=FANCI solenoid 1 domain, IPR026171=Fanconi anemia group I protein, IPR029313=FANCI solenoid 3 domain, IPR029315=FANCI solenoid 2 domain, IPR029312=FANCI helical domain 2, IPR029314=FANCI solenoid 4 domain" CG13745 16-Dec-15 2015_12 "ENSDARG00000026224(zgc:152941),ENSDARG00000070354(fanci)" ENSXETG00000017742(FANCI) ENSMUSG00000039187(Fanci) ENSG00000140525(FANCI) viable FBgn0034803 CG9849 http://flybase.net/reports/FBgn0034803.html protein_coding_gene 0007521=muscle cell fate determination 0005576=extracellular region IPR003137=PA domain CG9849 16-Dec-15 2015_12 WBGene00020322(T07F12.2) ENSXETG00000011777(C2orf7) ENSMUSG00000030008(1700040I03Rik) ENSG00000135617(PRADC1) viable embryonic/larval salivary gland FBgn0051752 CG31752 http://flybase.net/reports/FBgn0051752.html FBgn0032718 protein_coding_gene CG10599 CG31752 16-Dec-15 2015_12 viable DRSC22599 K -0.315661475 0.552585453 0.027950964 -0.70852202 2.693544161 -0.079404907 FBgn0023496 Lip1 Lipase 1 http://flybase.net/reports/FBgn0023496.html protein_coding_gene "0004806=triglyceride lipase activity, 0016298=lipase activity" "0006629=lipid metabolic process, 0007586=digestion" "Lip, Lipase1, LIP1Dm, CG7279, dilp1, lipase 1, dLip1, Dmlip1, lip1" "IPR029058=Alpha/Beta hydrolase fold, IPR025483=Lipase, eukaryotic, IPR006693=Partial AB-hydrolase lipase domain" CG7279 16-Dec-15 2015_12 ENSDARG00000018529(lipf) "YLR020C(YEH2),YLL012W(YEH1)" "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" " adult stage | female , larval stage && pupal stage , adult stage | male , embryonic stage | late , embryonic stage | stage >=14 " " embryonic/larval pharynx

, embryonic/larval proventriculus

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0262485 CG43075 http://flybase.net/reports/FBgn0262485.html protein_coding_gene CG43075 16-Dec-15 2015_12 FBgn0043967 U5E3sis U5E3sis http://flybase.net/reports/FBgn0043967.html gene 0009950=dorsal/ventral axis specification 16-Dec-15 2015_12 FBgn0083976 CG34140 http://flybase.net/reports/FBgn0083976.html "FBan0007042, FBgn0035105" protein_coding_gene "0003723=RNA binding, 0009982=pseudouridine synthase activity" 0001522=pseudouridine synthesis CG7042 "IPR020094=Pseudouridine synthase I, TruA, N-terminal, IPR001406=Pseudouridine synthase I, TruA, IPR020103=Pseudouridine synthase, catalytic domain, IPR020097=Pseudouridine synthase I, TruA, alpha/beta domain, IPR020095=Pseudouridine synthase I, TruA, C-terminal" CG34140 16-Dec-15 2015_12 WBGene00022250(Y73B6BL.29) ENSXETG00000011145(PUSL1) ENSMUSG00000051557(Pusl1) ENSG00000169972(PUSL1) "viable,fertile" FBgn0034363 CG5327 http://flybase.net/reports/FBgn0034363.html FBgn0045988 protein_coding_gene NEST:bs33e07 "IPR008560=Protein of unknown function DUF842, eukaryotic" CG5327 16-Dec-15 2015_12 ENSDARG00000040148(fam136a) WBGene00014022(ZK637.2) ENSXETG00000008511(FAM136A) ENSMUSG00000057497(Fam136a) ENSG00000035141(FAM136A) viable DRSC06930 K 0.175423074 0.010592763 0.998783334 0.601073732 3.331109329 0.389815284 FBgn0263588 CR43613 http://flybase.net/reports/FBgn0263588.html non_protein_coding_gene lincRNA.892 CR43613 16-Dec-15 2015_12 FBgn0019812 fs(2)R female sterile (2) Ruplekha http://flybase.net/reports/FBgn0019812.html gene 16-Dec-15 2015_12 "female sterile,viable,female,poor" FBgn0037236 Skp2 http://flybase.net/reports/FBgn0037236.html FBan0009772 protein_coding_gene 0004842=ubiquitin-protein transferase activity "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0007113=endomitotic cell cycle, 0035220=wing disc development, 0048749=compound eye development, 0000278=mitotic cell cycle, 0006511=ubiquitin-dependent protein catabolic process, 0045787=positive regulation of cell cycle, 0031647=regulation of protein stability" 0019005=SCF ubiquitin ligase complex "SKP2, 153298_at, FBXL1, Skp2, CG9772, dSkp2" "IPR006553=Leucine-rich repeat, cysteine-containing subtype, IPR001810=F-box domain" CG9772 16-Dec-15 2015_12 ENSDARG00000004937(skp2) WBGene00018613(skpt-1) ENSXETG00000004797(SKP2) ENSMUSG00000054115(Skp2) "endomitotic cell cycle defective,mitotic cell cycle defective,increased cell death,lethal - all die before end of P-stage,some die during P-stage,viable,visible,decreased cell number,somatic clone" "embryonic/larval salivary gland,embryonic/larval brain,eye disc,wing disc,trichogen cell,wing hair,eye,somatic clone,wing margin,scutellum,mesothoracic tergum,chaeta" FBgn0266788 CR45253 http://flybase.net/reports/FBgn0266788.html non_protein_coding_gene lincRNA.540 CR45253 16-Dec-15 2015_12 FBgn0037183 CG14451 http://flybase.net/reports/FBgn0037183.html protein_coding_gene 0046872=metal ion binding "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG14451 16-Dec-15 2015_12 viable DRSC11708 I 0.507167396 -2.021058542 -0.557611659 0.372803626 -0.23982946 0.415282259 FBgn0266703 CR45193 http://flybase.net/reports/FBgn0266703.html non_protein_coding_gene lincRNA.793 CR45193 16-Dec-15 2015_12 FBgn0264635 cincher cincher http://flybase.net/reports/FBgn0264635.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0040053 CG17674 http://flybase.net/reports/FBgn0040053.html protein_coding_gene 16-Dec-15 2015_12 FBgn0015963 l(2)46DEa lethal (2) 46DEa http://flybase.net/reports/FBgn0015963.html gene group 5 16-Dec-15 2015_12 "lethal,recessive" FBgn0038453 CG10326 http://flybase.net/reports/FBgn0038453.html protein_coding_gene 0005887=integral component of plasma membrane CG10326 16-Dec-15 2015_12 ENSDARG00000054578(arl6ip1) ENSXETG00000002943(ARL6IP1) ENSMUSG00000030654(Arl6ip1) ENSG00000170540(ARL6IP1) "viable,fertile" DRSC14231 K 0.423422477 -1.159857152 0.550802758 0.499688451 2.509930766 0.834729044 FBgn0004738 l(3)85De lethal (3) 85De http://flybase.net/reports/FBgn0004738.html gene 16-Dec-15 2015_12 lethal FBgn0039984 CG17473 http://flybase.net/reports/FBgn0039984.html protein_coding_gene 16-Dec-15 2015_12 FBgn0022994 ophthalmosa ophthalmosa http://flybase.net/reports/FBgn0022994.html gene opt 16-Dec-15 2015_12 FBgn0260615 2L3064 http://flybase.net/reports/FBgn0260615.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 viable "dorsal air sac primordium,somatic clone" FBgn0265967 CR44754 http://flybase.net/reports/FBgn0265967.html non_protein_coding_gene CR44754 16-Dec-15 2015_12 FBgn0250841 CG17242 http://flybase.net/reports/FBgn0250841.html "FBgn0042188, FBgn0066888" protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0032504=multicellular organism reproduction" 0005615=extracellular space "anon-SAGE:Wang-110, SPH187" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG17242 16-Dec-15 2015_12 FBgn0002057 l(2)40Fa lethal (2) 40Fa http://flybase.net/reports/FBgn0002057.html gene "40Fa, l(2)EMS56-8, 40-18, GroupIX, l(2Lh)Fa" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,dominant,lethal" eye FBgn0002233 l(3)68Bf lethal (3) 68Bf http://flybase.net/reports/FBgn0002233.html gene "l(3)B76, l(3)K" 16-Dec-15 2015_12 "visible,recessive,lethal,polyphasic" "leg,wing" FBgn0264294 Cyt-b5 Cytochrome b5 http://flybase.net/reports/FBgn0264294.html "FBgn0033189, FBgn0010500, FBgn0064864, FBgn0064982, FBgn0015930, FBgn0033181, FBgn0022277" protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding" "0035206=regulation of hemocyte proliferation, 0051726=regulation of cell cycle, 0002168=instar larval development, 0045610=regulation of hemocyte differentiation" "0005811=lipid particle, 0016020=membrane, 0043231=intracellular membrane-bounded organelle, 0012505=endomembrane system" "BcDNA:RE66521, l(2)k00107, BcDNA:GH02503, 1857, lethal (2) k00107, CG2140, dpld, CYT-B5, dappled, Cyt-b5, CYTB5, l(2)01857" "IPR018506=Cytochrome b5, heme-binding site, IPR001199=Cytochrome b5-like heme/steroid binding domain" CG2140 16-Dec-15 2015_12 "ENSDARG00000053954(cyb5b),ENSDARG00000055643(cyb5a)" WBGene00007848(C31E10.7) "ENSXETG00000023560(cyb5),ENSXETG00000017858(cyb5-m)" ENSMUSG00000024646(Cyb5) "ENSG00000166347(CYB5A),ENSG00000103018(CYB5B)" FBgn0082998 snoRNA:ë¬28S-1192d snoRNA:ë¬28S-1192d http://flybase.net/reports/FBgn0082998.html snoRNA_gene "CR34594, Psi28S-1192d, chrX:16977850..16978043, psi28S-1192d" CR34594 16-Dec-15 2015_12 FBgn0040477 cid centromere identifier http://flybase.net/reports/FBgn0040477.html "FBgn0033843, FBgn0063052" protein_coding_gene "0046982=protein heterodimerization activity, 0005515=protein binding, 0003677=DNA binding, 0003777=microtubule motor activity" "0007080=mitotic metaphase plate congression, 0022008=neurogenesis, 0051225=spindle assembly, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0051382=kinetochore assembly, 0031937=positive regulation of chromatin silencing, 0006333=chromatin assembly or disassembly, 0051383=kinetochore organization, 0007059=chromosome segregation, 0000022=mitotic spindle elongation" "0000780=condensed nuclear chromosome, centromeric region, 0000788=nuclear nucleosome, 0043505=CENP-A containing nucleosome, 0000941=condensed nuclear chromosome inner kinetochore, 0000776=kinetochore, 0000775=chromosome, centromeric region" "CENP-A/CID, cenpA, CG13329, Centromere identifier, CID/CENP-A, Cenp-A, cenH3, CENPA, CenH3, Centromere Identifier, BcDNA:RE21270, centromere protein A, Cid[Mel], Centromere identifier protein, CENP-A/Cid, Centromeric Histone H3, CID, CenH3[Cid], CenpA, CenH3[CID], CenpA/CID, CENH3, CENP-A, Cid" "IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A, IPR009072=Histone-fold" CG13329 16-Dec-15 2015_12 "WBGene00001831(hcp-3),WBGene00010036(cpar-1)" " egg stage | fertilized egg , adult stage , embryonic stage " " male pronucleus

, spermatid

, female pronucleus

" "mitotic cell cycle defective,visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,cell cycle defective" "condensed nuclear chromosome,metaphase,nucleus,spindle,mitotic cell cycle,mitotic anaphase,anaphase & condensed nuclear chromosome,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,chromosome,anaphase,telophase,metaphase plate" FBgn0060839 l(3)S049514 lethal (3) S049514 http://flybase.net/reports/FBgn0060839.html gene 0495/14 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0015850 anon-10Cc anon-10Cc http://flybase.net/reports/FBgn0015850.html gene unnamed 16-Dec-15 2015_12 FBgn0263943 BG00297 http://flybase.net/reports/FBgn0263943.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0065234 l(2)SH2167 lethal (2) SH2167 http://flybase.net/reports/FBgn0065234.html gene l(2)SH2 2167 16-Dec-15 2015_12 "lethal,recessive" FBgn0041624 Or65b Odorant receptor 65b http://flybase.net/reports/FBgn0041624.html "FBgn0052402, FBtr0077005, FBpp0076713" protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "DOR63, 65b, CG32402, LU27.1" "IPR004117=Olfactory receptor, Drosophila" CG32402 16-Dec-15 2015_12 viable FBgn0040347 mus81 mus81 http://flybase.net/reports/FBgn0040347.html FBgn0029547 protein_coding_gene "0004518=nuclease activity, 0008821=crossover junction endodeoxyribonuclease activity, 0003677=DNA binding" "0006281=DNA repair, 0007095=mitotic G2 DNA damage checkpoint, 0007131=reciprocal meiotic recombination" "EG:BACR7A4.16, Mus81, CG3026" "IPR010996=DNA polymerase beta-like, N-terminal domain, IPR011335=Restriction endonuclease type II-like, IPR027420=DNA polymerase beta, N-terminal domain, IPR020819=DNA repair nuclease, XPF-type/Helicase, IPR006166=ERCC4 domain" CG3026 16-Dec-15 2015_12 WBGene00016602(mus-81) ENSXETG00000020588(Q640B4_XENTR) ENSMUSG00000024906(Mus81) ENSG00000172732(MUS81) "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,chemical sensitive" FBgn0263981 CR43730 http://flybase.net/reports/FBgn0263981.html non_protein_coding_gene CR43730 16-Dec-15 2015_12 FBgn0016927 smi26D smell impaired 26D http://flybase.net/reports/FBgn0016927.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0011667 Mst40 Male-specific RNA 40 http://flybase.net/reports/FBgn0011667.html "FBgn0045090, FBgn0045255" gene "0005737=cytoplasm, 0005634=nucleus" "ORF1, Male-specific transcript 40, bs35e07.y1, NEST:bs35e07, bs18c05.y1, mst40, NEST:bs18c05" 16-Dec-15 2015_12 FBgn0052554 CG32554 http://flybase.net/reports/FBgn0052554.html FBgn0030875 protein_coding_gene CG7871 CG32554 16-Dec-15 2015_12 FBgn0001004 Fs(2)Ugr Female sterile (2) Ugra http://flybase.net/reports/FBgn0001004.html gene "0007306=eggshell chorion assembly, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "Fs(2)Ugra, fs(2)Ugra, Fs(2)Sz12, Ugra" 16-Dec-15 2015_12 "female sterile soma-dependent,dominant,female sterile" "nurse cell,egg,egg chamber,vitelline membrane,inner chorionic layer,endochorion,oocyte & cytoplasm" FBgn0060389 l(3)S133807 lethal (3) S133807 http://flybase.net/reports/FBgn0060389.html gene 1338/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0265897 CR44686 http://flybase.net/reports/FBgn0265897.html non_protein_coding_gene CR44686 16-Dec-15 2015_12 FBgn0052459 CG32459 http://flybase.net/reports/FBgn0052459.html "FBgn0037196, FBgn0044600" protein_coding_gene "CG8220, anon-WO0140519.31" CG32459 16-Dec-15 2015_12 "viable,fertile" FBgn0024709 anon-76Ca anon-76Ca http://flybase.net/reports/FBgn0024709.html gene unnamed 16-Dec-15 2015_12 FBgn0005218 l(3)ET10 lethal Elaine Tasaka 10 http://flybase.net/reports/FBgn0005218.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,visible" tergite FBgn0046646 anon-38D.20 anon-38D.20 http://flybase.net/reports/FBgn0046646.html gene 38D.20 16-Dec-15 2015_12 FBgn0053355 5SrRNA:CR33355 5SrRNA:CR33355 http://flybase.net/reports/FBgn0053355.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33355 CR33355 16-Dec-15 2015_12 FBgn0259678 sqa spaghetti-squash activator http://flybase.net/reports/FBgn0259678.html "FBgn0033441, FBgn0050004" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0004687=myosin light chain kinase activity, 0005524=ATP binding" "0008360=regulation of cell shape, 0046777=protein autophosphorylation, 0032008=positive regulation of TOR signaling, 0007015=actin filament organization, 0006468=protein phosphorylation, 0006914=autophagy" "CG1776, CG42347, CG30004, FBgn0259678, MLCK-like" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR020675=Myosin light chain kinase-related, IPR017441=Protein kinase, ATP binding site" CG42347 16-Dec-15 2015_12 FBgn0019954 Nrt::wg Nrt::wg http://flybase.net/reports/FBgn0019954.html engineered_fusion_gene N-Wg 16-Dec-15 2015_12 "wing & macrochaetaC-765,macrochaeta,ectopic,denticle belt" FBgn0028038 l(3)S100209 lethal (3) S100209 http://flybase.net/reports/FBgn0028038.html gene 1002/09 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0011743 Arp53D Actin-related protein 53D http://flybase.net/reports/FBgn0011743.html protein_coding_gene 0005200=structural constituent of cytoskeleton 0007010=cytoskeleton organization "0015629=actin cytoskeleton, 0005884=actin filament" "CG5409, ARP53D, Actr53D, arp5, arp53D" "IPR004000=Actin family, IPR020902=Actin/actin-like conserved site" CG5409 16-Dec-15 2015_12 " pupal stage , spermatogenesis && adult stage , adult stage | male " testis

viable FBgn0067879 Mod(Prat:bw)2-4 Mod(Prat:bw)2-4 http://flybase.net/reports/FBgn0067879.html gene Mod-2-4 16-Dec-15 2015_12 "male sterile,recessive" FBgn0042199 CG13713 http://flybase.net/reports/FBgn0042199.html FBgn0040702 protein_coding_gene 0032879=regulation of localization "CG18465, HL2" IPR007970=Protein of unknown function DUF733 CG13713 16-Dec-15 2015_12 viable FBgn0038804 CG10877 http://flybase.net/reports/FBgn0038804.html protein_coding_gene 0003824=catalytic activity "IPR003673=CoA-transferase family III, IPR023606=CoA-transferase family III domain" CG10877 16-Dec-15 2015_12 ENSXETG00000015599(C7orf10) ENSMUSG00000055137(5033411D12Rik) ENSG00000175600(C7orf10) viable FBgn0027592 MED15 Mediator complex subunit 15 http://flybase.net/reports/FBgn0027592.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0006357=regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" 0016592=mediator complex "mediator15, CG4184, dARC105, med15, Med9/ARC105, Arc105, Med15, BcDNA:GH03922" "IPR019087=Mediator complex, subunit Med15, IPR003101=Coactivator CBP, KIX domain" CG4184 16-Dec-15 2015_12 ENSDARG00000014292(med15) ENSXETG00000004253(MED15) ENSMUSG00000012114(Med15) ENSG00000099917(MED15) "visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage" "wing margin,wing,wing vein L2,distal,wing sensillum,ectopic,wing disc" DRSC00267 IK 0.93621912 1.842426673 0.26150271 1.259472352 0.93466722 2.099781538 FBgn0031164 CG1724 http://flybase.net/reports/FBgn0031164.html FBgn0061459 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0006626=protein targeting to mitochondrion, 0015031=protein transport" 0005744=mitochondrial inner membrane presequence translocase complex BcDNA:AT13347 "IPR005678=Mitochondrial inner membrane translocase complex, subunit Tim17, IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24" CG1724 16-Dec-15 2015_12 "ENSDARG00000060124(timm17b),ENSDARG00000029510(timm17a)" YJL143W(TIM17) WBGene00017119(E04A4.5) ENSXETG00000007983(timm17a) "ENSMUSG00000062580(Timm17a),ENSMUSG00000031158(Timm17b)" "ENSG00000126768(TIMM17B),ENSG00000134375(TIMM17A)" viable FBgn0002135 l(2)K224 lethal (2) K224 http://flybase.net/reports/FBgn0002135.html gene 16-Dec-15 2015_12 lethal FBgn0032014 CG7840 http://flybase.net/reports/FBgn0032014.html protein_coding_gene 0003865=3-oxo-5-alpha-steroid 4-dehydrogenase activity "0006488=dolichol-linked oligosaccharide biosynthetic process, 0016095=polyprenol catabolic process, 0019348=dolichol metabolic process" "0016021=integral component of membrane, 0005737=cytoplasm" cg7840 "IPR001104=3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal" CG7840 16-Dec-15 2015_12 ENSDARG00000043307(srd5a3) YIL049W(DFG10) WBGene00007102(B0024.13) ENSXETG00000021063() ENSMUSG00000029233(Srd5a3) ENSG00000128039(SRD5A3) viable FBgn0024251 bbx bobby sox http://flybase.net/reports/FBgn0024251.html "FBgn0014083, FBgn0052527, FBtr0077200, FBpp0076899, FBtr0077201, FBpp0076900, FBtr0077202, FBpp0076901" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "tu2, CG32527, CG1414, anon-19Fb" IPR009071=High mobility group box domain CG1414 16-Dec-15 2015_12 ENSDARG00000012699 ENSMUSG00000022641(Bbx) ENSG00000114439(BBX) "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0265165 CR44234 http://flybase.net/reports/FBgn0265165.html non_protein_coding_gene lincRNA.762 CR44234 16-Dec-15 2015_12 FBgn0262412 mir-1008 mir-1008 stem loop http://flybase.net/reports/FBgn0262412.html "FBgn0250804, FBgn0262250" miRNA_gene "miR-1008, CR42957, dme-mir-1008" CR42957 16-Dec-15 2015_12 viable FBgn0000020 abt abnormal tergites http://flybase.net/reports/FBgn0000020.html gene 16-Dec-15 2015_12 "visible,viable,male,male sterile,partially,recessive,male semi-sterile,body color defective" "adult abdomen & microchaeta,eye,ommatidium,wing,wing vein,tergite,adult abdomen" FBgn0043554 Su(roDOM)519 Su(roDOM)519 http://flybase.net/reports/FBgn0043554.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "viable,visible,dominant" eye FBgn0044049 Ilp4 Insulin-like peptide 4 http://flybase.net/reports/FBgn0044049.html "FBgn0019856, FBgn0036048, FBgn0047136" protein_coding_gene "0005158=insulin receptor binding, 0005179=hormone activity" "0030536=larval feeding behavior, 0008286=insulin receptor signaling pathway" 0005615=extracellular space "Drosophila insulin/relaxin-like peptide, Dilp, DILP4, unnamed, insulin-like peptide-4, mes3, Dilp 4, Ilp-4, DILP, Dirlp, insulin-like peptide, A, dILP4, anon-EST:CLB3, BcDNA:RE27042, Dilp4, dilp4, Ilp, CG6736, ilp4, dilp, Mes3, insulin-like peptide 4, dilp-4, DILP-4, Drosophila insulin-like peptide 4" "IPR022353=Insulin, conserved site, IPR016179=Insulin-like, IPR022352=Insulin family" CG6736 16-Dec-15 2015_12 " embryonic stage | stage >5 , larval stage | third instar , embryonic stage | cellular blastoderm , embryonic stage | stage 12-16 , embryonic stage | stage 2-12 , embryonic stage | stage 5 " " mesoderm

, embryonic/larval midgut

, mesoderm anlage

, anterior midgut proper primordium

" "feeding behavior defective,large body,viable" embryonic/larval neuroblast FBgn0035763 CG8602 http://flybase.net/reports/FBgn0035763.html "FBgn0062051, FBgn0062076" protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "anon-WO0118547.382, anon-WO0118547.349" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8602 16-Dec-15 2015_12 ENSXETG00000012456(MFSD1) ENSMUSG00000027775(Mfsd1) ENSG00000118855(MFSD1) FBgn0016953 tilJ touch insensitive larva J http://flybase.net/reports/FBgn0016953.html gene line 366 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective,uncoordinated" FBgn0044455 EP3561 EP3561 http://flybase.net/reports/FBgn0044455.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0037779 CG12811 http://flybase.net/reports/FBgn0037779.html protein_coding_gene CG12811 16-Dec-15 2015_12 FBgn0033190 CG2137 http://flybase.net/reports/FBgn0033190.html FBgn0001129 protein_coding_gene "0005509=calcium ion binding, 0004368=glycerol-3-phosphate dehydrogenase activity" "0006072=glycerol-3-phosphate metabolic process, 0055114=oxidation-reduction process, 0006071=glycerol metabolic process" "0005739=mitochondrion, 0009331=glycerol-3-phosphate dehydrogenase complex" "GPO, gpo-3, 146747_at, GPO-3, alpha-GPO, Gpo" "IPR011992=EF-hand domain pair, IPR006076=FAD dependent oxidoreductase, IPR002048=EF-hand domain, IPR000447=FAD-dependent glycerol-3-phosphate dehydrogenase" CG2137 16-Dec-15 2015_12 YIL155C(GUT2) viable FBgn0002558 lop lobula plateless http://flybase.net/reports/FBgn0002558.html gene N684 16-Dec-15 2015_12 neuroanatomy defective lobula plate FBgn0011634 l(2)T57h7 lethal (2) T57h7 http://flybase.net/reports/FBgn0011634.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0259876 Cap-G Chromosome associated protein G http://flybase.net/reports/FBgn0259876.html "FBgn0250905, FBgn0033795, FBgn0033796, FBgn0033797, FBgn0050057, FBgn0061377, FBgn0069198, FBgn0085467, FBan0017054, FBgn0002077" protein_coding_gene "0070194=synaptonemal complex disassembly, 0000281=mitotic cytokinesis, 0000819=sister chromatid segregation, 0007052=mitotic spindle organization, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0000070=mitotic sister chromatid segregation, 0022008=neurogenesis, 0007076=mitotic chromosome condensation" "0000775=chromosome, centromeric region, 0000785=chromatin, 0000796=condensin complex, 0005720=nuclear heterochromatin, 0005634=nucleus" "CAP-G, l(2)49Ff, cap-G, l(2)vr9, DCAP-G, Cap-G, dCAP-G, cap-g, CG17054, dcap-g, CG34438, CG30057, dCap-G, DmCAP-G, vr-9, CapG, vr9, CG13327, lethal (2) 49Ff" "IPR011989=Armadillo-like helical, IPR025977=Nuclear condensin complex subunit 3, C-terminal domain, IPR016024=Armadillo-type fold, IPR027165=Condensin complex subunit 3" CG34438 16-Dec-15 2015_12 ENSDARG00000070109 ENSXETG00000023826(hcap-g) ENSMUSG00000015880 ENSG00000109805(NCAPG) DRSC06653 IE 3.254948018 0.570605478 1.724249188 0.641673269 -0.18038739 1.071479412 FBgn0266418 wake wide awake http://flybase.net/reports/FBgn0266418.html "FBgn0039000, FBgn0038998, FBgn0038999, FBgn0261572" protein_coding_gene 0050811=GABA receptor binding "0055059=asymmetric neuroblast division, 0061172=regulation of establishment of bipolar cell polarity, 0007165=signal transduction, 0000132=establishment of mitotic spindle orientation, 0045938=positive regulation of circadian sleep/wake cycle, sleep, 0098722=asymmetric stem cell division" "0005813=centrosome, 0005819=spindle" "CG45058, CG17623, CG6954, ban, banderuola, CG17622, CG42686" "IPR000159=Ras-associating (RA) domain, IPR003961=Fibronectin type III, IPR013783=Immunoglobulin-like fold, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG45058 16-Dec-15 2015_12 WBGene00019935(R07E4.1) FBgn0266100 CG44837 http://flybase.net/reports/FBgn0266100.html "FBgn0036223, FBgn0085449, FBgn0036215, FBgn0036216" protein_coding_gene 0016805=dipeptidase activity 0006508=proteolysis "CG34420, rugose, CG14129, CG14126, CG5917" IPR008257=Renal dipeptidase family CG44837 16-Dec-15 2015_12 DRSC10133 I -0.636539603 -1.534662136 0.855732895 -1.464536939 0.727738114 -0.04722746 FBgn0037068 Cpr78Cb Cuticular protein 78Cb http://flybase.net/reports/FBgn0037068.html "FBgn0026288, FBgn0061402" protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG7663, anon-EST:ParkEST240, BcDNA:RE38359, DmelCpr78Cb" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG7663 16-Dec-15 2015_12 viable FBgn0026357 Su(SuRaf1)10 Su(SuRaf1)10 http://flybase.net/reports/FBgn0026357.html gene Su[Su(Raf)1]10 16-Dec-15 2015_12 "lethal,recessive" FBgn0021805 l(2)k16801 lethal (2) k16801 http://flybase.net/reports/FBgn0021805.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0250733 l(3)S006313 lethal (3) S006313 http://flybase.net/reports/FBgn0250733.html gene l(3)s006313 16-Dec-15 2015_12 lethal FBgn0266459 CG45084 http://flybase.net/reports/FBgn0266459.html protein_coding_gene Dromel_CG4824_FBtr0080804_bicc_uORF CG45084 16-Dec-15 2015_12 FBgn0023465 anon-56Cc anon-56Cc http://flybase.net/reports/FBgn0023465.html gene 16-Dec-15 2015_12 adult stage && oogenesis stage " ovary

, nurse cell

" FBgn0051493 CG31493 http://flybase.net/reports/FBgn0051493.html FBgn0037474 protein_coding_gene 0032504=multicellular organism reproduction CG2640 IPR016181=Acyl-CoA N-acyltransferase CG31493 16-Dec-15 2015_12 viable FBgn0085308 CG34279 http://flybase.net/reports/FBgn0085308.html protein_coding_gene IPR002350=Kazal domain CG34279 16-Dec-15 2015_12 FBgn0086909 CG31751 http://flybase.net/reports/FBgn0086909.html "FBgn0051751, FBgn0032696, FBgn0032697, FBgn0023099" protein_coding_gene "CG15164, constitutive transcript, CG15163, anon-ct, ct" "IPR002575=Aminoglycoside phosphotransferase, IPR011009=Protein kinase-like domain" CG31751 16-Dec-15 2015_12 ENSXETG00000023889(AGPHD1) ENSMUSG00000035878(Agphd1) ENSG00000188266(AGPHD1) embryonic stage -- adult stage FBgn0265755 CR44562 http://flybase.net/reports/FBgn0265755.html non_protein_coding_gene CR44562 16-Dec-15 2015_12 FBgn0026438 Eaat2 Excitatory amino acid transporter 2 http://flybase.net/reports/FBgn0026438.html protein_coding_gene "0017153=sodium:dicarboxylate symporter activity, 0015183=L-aspartate transmembrane transporter activity, 0005369=taurine:sodium symporter activity, 0015501=glutamate:sodium symporter activity" "0006835=dicarboxylic acid transport, 0015734=taurine transport" "0016020=membrane, 0005886=plasma membrane" "dEaat2, sodium-dependent excitatory amino acid transporter 2, dEAAT2, excitatory amino acid transporter 2, CG3159, EAAT" "IPR001991=Sodium:dicarboxylate symporter, IPR018107=Sodium:dicarboxylate symporter, conserved site" CG3159 16-Dec-15 2015_12 "ENSDARG00000052138(LOC560802),ENSDARG00000009563(slc1a2b),ENSDARG00000054836" "WBGene00001620(glt-1),WBGene00001624(glt-6),WBGene00001621(glt-3),WBGene00001623(glt-5)" "ENSXETG00000007555(SLC1A2),ENSXETG00000021225()" ENSMUSG00000005089(Slc1a2) ENSG00000110436(SLC1A2) " embryonic stage | stage 15-16 , embryonic stage | stage 17 , adult stage , embryonic stage | stage 16-17 , larval stage | third instar " " Bolwig's organ | presumptive

, interneuron

, midline glial cell

, ocellus

, sense organ & neuron | subset

, larval central nervous system

, adult head

, retina

, ventral nerve cord

,

anterior , glial cell

, CNS glial cell | subset

" "viable,chemosensitive behavior defective" FBgn0259222 CG42322 http://flybase.net/reports/FBgn0259222.html "FBgn0038825, FBgn0051203, FBgn0038822, FBgn0038824" protein_coding_gene "CG15690, CG31203, CG15688, CG15689" IPR026505=Solute carrier family 35 member F3/F4 CG42322 16-Dec-15 2015_12 FBgn0031751 CG9016 http://flybase.net/reports/FBgn0031751.html "FBgn0045080, FBgn0045083, FBgn0045139, FBgn0045142, FBgn0045158, FBgn0045175, FBgn0045187, FBgn0045193, FBgn0045213, FBgn0045226, FBgn0045230, FBgn0045242, FBgn0045258, FBgn0045277, FBgn0045279, FBgn0045306, FBgn0045311, FBgn0045338, FBgn0045342, FBgn0045358, FBgn0045362, FBgn0045376, FBgn0045401, FBgn0045421, FBgn0063317" protein_coding_gene "bs05g03.y1, bs28b03.y1, bs22a02.y1, bs29e04.y1, bs19d06.y1, bs10f09.y1, bs36f07.y1, BcDNA:AT19175, bs03c03.y1, bs10d11.y1, bs07e11.y1, bs20d08.y1, bs27b06.y1, bs13h06.y1, NEST:bs20d08, bs14b11.y1, bs29f11.y1, bs16c10.y1, bs21a02.y1, bs16d01.y1, NEST:bs09a09, bs24f02.y1, NEST:bs36a03, bs09c06.y1, NEST:bs24f02, bs25d03.y1, bs18b05.y1" CG9016 16-Dec-15 2015_12 "viable,fertile" FBgn0003935 snRNA:U5:34A small nuclear RNA U5 at 34AB http://flybase.net/reports/FBgn0003935.html "FBgn0003932, FBgn0051853" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "U5 snRNA, U5, small nuclear RNA U5, snRNA[[3]], CR31853, K2, U5:34A, U5snRNA, snRNA3, U5 snRNA 34A, snRNA:U5:34AB, U5snRNA34AB, U5 small nuclear RNA, 34B U5, U5-34A, snRNA:U5, snRNA4, dU5" CR31853 16-Dec-15 2015_12 lethal FBgn0004686 mei-I1 meiotic I1 http://flybase.net/reports/FBgn0004686.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive" "meiosis I,spermatocyte,spermatid" FBgn0016782 anon-8Db anon-8Db http://flybase.net/reports/FBgn0016782.html gene 16-Dec-15 2015_12 FBgn0010866 l(3)05430 lethal (3) 05430 http://flybase.net/reports/FBgn0010866.html gene 0048598=embryonic morphogenesis 16-Dec-15 2015_12 "lethal,polyphasic,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,maternal effect" FBgn0035816 CG13685 http://flybase.net/reports/FBgn0035816.html protein_coding_gene CG13685 16-Dec-15 2015_12 FBgn0025773 l(3)89Ab lethal (3) 89Ab http://flybase.net/reports/FBgn0025773.html gene 16-Dec-15 2015_12 FBgn0005574 l(3)85Ej lethal (3) 85Ej http://flybase.net/reports/FBgn0005574.html gene 16-Dec-15 2015_12 lethal FBgn0022137 l(2)k06327 lethal (2) k06327 http://flybase.net/reports/FBgn0022137.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005398 pch parched http://flybase.net/reports/FBgn0005398.html "FBgn0000050, FBgn0001333, FBgn0003043, FBgn0004645" gene "EC2, doomed, addB, l(1)1Aa, l(1)d, l(1)7e, dmd, l[EC1], adult-lethal-B, l(1)HF310, EC1, l(1)[d], lEC1" 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" FBgn0001412 l(1)3Eb lethal (1) 3Eb http://flybase.net/reports/FBgn0001412.html gene GF332 16-Dec-15 2015_12 "lethal,recessive" "ovary,germline clone,follicle cell" FBgn0266468 noix http://flybase.net/reports/FBgn0266468.html gene 16-Dec-15 2015_12 "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0025753 l(3)93DFi lethal (3) 93DFi http://flybase.net/reports/FBgn0025753.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0069131 mei(2)yh15 mei(2)yh15 http://flybase.net/reports/FBgn0069131.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,female fertile" FBgn0267782 CR46113 http://flybase.net/reports/FBgn0267782.html non_protein_coding_gene CR46113 16-Dec-15 2015_12 FBgn0030876 CG6762 http://flybase.net/reports/FBgn0030876.html protein_coding_gene 0032542=sulfiredoxin activity 0055114=oxidation-reduction process "IPR016692=Sulfiredoxin, IPR003115=ParB/Sulfiredoxin" CG6762 16-Dec-15 2015_12 YKL086W(SRX1) ENSMUSG00000032802(Srxn1) ENSG00000172070(SRXN1) viable FBgn0036938 CG14187 http://flybase.net/reports/FBgn0036938.html protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion CG14187 16-Dec-15 2015_12 viable FBgn0052418 vito viriato http://flybase.net/reports/FBgn0052418.html FBgn0035634 protein_coding_gene "0007000=nucleolus organization, 0008284=positive regulation of cell proliferation, 0043066=negative regulation of apoptotic process, 0035214=eye-antennal disc development, 0030307=positive regulation of cell growth, 0045572=positive regulation of imaginal disc growth" 0005730=nucleolus "CG32418, CG10569" IPR019186=Nucleolar protein 12 CG32418 16-Dec-15 2015_12 ENSDARG00000038027(LOC100330592) ENSXETG00000015984(NOL12) ENSMUSG00000033099(Nol12) ENSG00000100101 "size defective,recessive,developmental rate defective,increased cell death,decreased cell number,somatic clone,decreased cell size,viable,visible" "eye,eye disc,somatic clone | third instar larval stage,embryonic/larval salivary gland,nucleolus | third instar larval stageptc-559.1,trichogen cell" FBgn0038332 CG6136 http://flybase.net/reports/FBgn0038332.html protein_coding_gene 0005507=copper ion binding 0055070=copper ion homeostasis "IPR005627=Copper homeostasis protein CutC, IPR023648=Copper homeostasis CutC domain" CG6136 16-Dec-15 2015_12 ENSDARG00000039853(LOC569010) WBGene00022702(cutc-1) ENSXETG00000003744(cutc) ENSMUSG00000025193(Cutc) ENSG00000119929(CUTC) viable FBgn0266895 CR45355 http://flybase.net/reports/FBgn0266895.html non_protein_coding_gene CR45355 16-Dec-15 2015_12 FBgn0061003 l(3)S026532 lethal (3) S026532 http://flybase.net/reports/FBgn0061003.html gene 0265/32 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0002087 l(2)52Ea lethal (2) 52Ea http://flybase.net/reports/FBgn0002087.html gene KL-32-1 16-Dec-15 2015_12 lethal FBgn0060997 l(3)S027114 lethal (3) S027114 http://flybase.net/reports/FBgn0060997.html gene 0271/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0032846 CG10721 http://flybase.net/reports/FBgn0032846.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process 38B.14 "IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain" CG10721 16-Dec-15 2015_12 ENSDARG00000033586(zgc:73254) WBGene00007744(C26D10.3) ENSXETG00000013520(PYROXD1) ENSMUSG00000041671(Pyroxd1) ENSG00000121350(PYROXD1) viable FBgn0033587 CG13218 http://flybase.net/reports/FBgn0033587.html protein_coding_gene CG13218 16-Dec-15 2015_12 viable FBgn0264295 CG43773 http://flybase.net/reports/FBgn0264295.html FBgn0031581 protein_coding_gene CG10039 CG43773 16-Dec-15 2015_12 FBgn0043050 anon-50Ea anon-50Ea http://flybase.net/reports/FBgn0043050.html gene "T2, t2" 16-Dec-15 2015_12 FBgn0265964 CR44751 http://flybase.net/reports/FBgn0265964.html non_protein_coding_gene CR44751 16-Dec-15 2015_12 FBgn0260279 GSd496 http://flybase.net/reports/FBgn0260279.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0001171 ha hair bristles http://flybase.net/reports/FBgn0001171.html gene 16-Dec-15 2015_12 "viable,male,female,reduced,male fertile,female sterile,recessive,visible" macrochaeta FBgn0005141 l(2)CA6 lethal (2) CA6 http://flybase.net/reports/FBgn0005141.html gene "l(1)br6, l(2)br6, lethal 6 in the black-reduced region" 16-Dec-15 2015_12 "lethal,recessive" FBgn0259979 CG17337 http://flybase.net/reports/FBgn0259979.html "FBgn0033035, FBgn0014099" protein_coding_gene "0034701=tripeptidase activity, 0008237=metallopeptidase activity, 0016805=dipeptidase activity" 0006508=proteolysis 0005576=extracellular region "anon-41Fb, transcription unit Y, Dm52, Y" "IPR017153=Glutathione degradosome, DUG1, IPR011650=Peptidase M20, dimerisation domain, IPR001261=ArgE/DapE/ACY1/CPG2/YscS, conserved site, IPR002933=Peptidase M20" CG17337 16-Dec-15 2015_12 ENSDARG00000003931(cndp2) YFR044C(DUG1) WBGene00003982(pes-9) ENSXETG00000023561(CNDP2) ENSMUSG00000024644(Cndp2) ENSG00000133313(CNDP2) embryonic stage embryonic/larval digestive system

FBgn0026619 Taz Tafazzin http://flybase.net/reports/FBgn0026619.html protein_coding_gene "0032577=phosphatidylcholine:cardiolipin O-linoleoyltransferase activity, 0016746=transferase activity, transferring acyl groups" "0032048=cardiolipin metabolic process, 0007291=sperm individualization, 0007006=mitochondrial membrane organization, 0032049=cardiolipin biosynthetic process, 0006644=phospholipid metabolic process" 0005739=mitochondrion "TAZ, dTAZ, tafazzin, tafazzins, CG8766" "IPR002123=Phospholipid/glycerol acyltransferase, IPR000872=Tafazzin" CG8766 16-Dec-15 2015_12 ENSDARG00000041421(taz) WBGene00006491(acl-3) ENSXETG00000003378(taz) ENSMUSG00000009995(Taz) ENSG00000102125(TAZ) "locomotor behavior defective,male sterile,recessive,viable,body color defective" "indirect flight muscle & mitochondrion,mitochondrial crista,mitochondrion,individualization stage spermatid,spermatid cyst,mesothoracic tergum" FBgn0030467 CG1764 http://flybase.net/reports/FBgn0030467.html protein_coding_gene 0016403=dimethylargininase activity cg1764 IPR003198=Amidinotransferase CG1764 16-Dec-15 2015_12 ENSDARG00000057841(si:dkey-46a12.1) "ENSXETG00000024074(ddah2),ENSXETG00000003095()" "ENSMUSG00000028194(Ddah1),ENSMUSG00000007039(Ddah2)" "ENSG00000153904(DDAH1),ENSG00000111980,ENSG00000213722(DDAH2),ENSG00000206395" "viable,fertile" FBgn0065350 l(2)SH1806 lethal (2) SH1806 http://flybase.net/reports/FBgn0065350.html gene l(2)SH2 1806 16-Dec-15 2015_12 "lethal,recessive" FBgn0027788 Hey Hairy/E(spl)-related with YRPW motif http://flybase.net/reports/FBgn0027788.html FBgn0027789 protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0048664=neuron fate determination, 0045746=negative regulation of Notch signaling pathway" 0005634=nucleus "Hairy/E(spl), bHLHe44, Hairy/E(spl)-related, hey, CG11194, hesr-1, Hairy/E(spl) related with YRPW motif, Hairy and enhancer of split related protein, d-hey, hairy and enhancer of split related-1, Hesr-1, dHey" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG11194 16-Dec-15 2015_12 "ENSDARG00000013441(hey2),ENSDARG00000070538(hey1),ENSDARG00000055798(heyl)" "ENSXETG00000007864(hey1),ENSXETG00000021844(HEY2)" "ENSMUSG00000040289(Hey1),ENSMUSG00000019789(Hey2)" "ENSG00000164683(HEY1),ENSG00000135547(HEY2),ENSG00000163909(HEYL)" "lethal - all die before end of second instar larval stage,some die during embryonic stage,majority die during first instar larval stage,neuroanatomy defective" "RP2 motor neuron,RP2sib neuron,dMP2 neuron,vMP2 neuron" FBgn0265151 CR44220 http://flybase.net/reports/FBgn0265151.html non_protein_coding_gene CR44220 16-Dec-15 2015_12 FBgn0266322 CR44987 http://flybase.net/reports/FBgn0266322.html non_protein_coding_gene CR44987 16-Dec-15 2015_12 FBgn0011316 l(3)j1D5 lethal (3) j1D5 http://flybase.net/reports/FBgn0011316.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262999 CG43307 http://flybase.net/reports/FBgn0262999.html protein_coding_gene lincRNA.52 IPR002350=Kazal domain CG43307 16-Dec-15 2015_12 FBgn0039151 CG13607 http://flybase.net/reports/FBgn0039151.html protein_coding_gene 150482_at CG13607 16-Dec-15 2015_12 FBgn0060994 l(3)S027318b lethal (3) S027318b http://flybase.net/reports/FBgn0060994.html gene 0273/18 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0043010 Fsn F-box synaptic protein http://flybase.net/reports/FBgn0043010.html FBgn0033811 protein_coding_gene "0005515=protein binding, 0004842=ubiquitin-protein transferase activity" "0007274=neuromuscular synaptic transmission, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0045732=positive regulation of protein catabolic process" "0005938=cell cortex, 0019005=SCF ubiquitin ligase complex, 0005634=nucleus, 0005737=cytoplasm, 0045495=pole plasm" "DFsn, fsn, Wallenstein, BEST:GH20696, dFsn, CG4643, FBXO2, Wals" "IPR003877=SPRY domain, IPR001810=F-box domain, IPR001870=B30.2/SPRY domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG4643 16-Dec-15 2015_12 "ENSDARG00000069060,ENSDARG00000071490,ENSDARG00000071492(fbxo45)" WBGene00001499(fsn-1) ENSXETG00000011811(FBXO45) ENSMUSG00000035764(Fbxo45) ENSG00000174013(FBXO45) "partially lethal - majority live,maternal effect,viable,male sterile,neuroanatomy defective,neurophysiology defective,body color defective" "type I bouton,supernumerary,embryonic/larval neuromuscular junction,pole cell,maternal effect,mesothoracic tergum" FBgn0019674 mor(1)5 mortality gene (1)5 http://flybase.net/reports/FBgn0019674.html gene 16-Dec-15 2015_12 short lived FBgn0023137 WppF White prepupal locus F http://flybase.net/reports/FBgn0023137.html gene "15, 8" 16-Dec-15 2015_12 FBgn0029820 CG16721 http://flybase.net/reports/FBgn0029820.html protein_coding_gene 0019933=cAMP-mediated signaling 0005634=nucleus IPR008862=T-complex 11 CG16721 16-Dec-15 2015_12 "ENSDARG00000027316(zgc:73347),ENSDARG00000031890(tcp11l1)" WBGene00010875(M05D6.2) "ENSXETG00000017957(TCP11L1),ENSXETG00000006691(TCP11L2)" "ENSMUSG00000027175(Tcp11l1),ENSMUSG00000020034(Tcp11l2),ENSMUSG00000062859(Tcp11),ENSMUSG00000058252(1700008I05Rik)" "ENSG00000166046(TCP11L2),ENSG00000176148(TCP11L1),ENSG00000124678(TCP11),ENSG00000215029,ENSG00000215046" viable FBgn0061101 l(3)S008831b lethal (3) S008831b http://flybase.net/reports/FBgn0061101.html gene 0088/31 16-Dec-15 2015_12 "lethal,recessive" FBgn0027263 l(1)G0223 lethal (1) G0223 http://flybase.net/reports/FBgn0027263.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001071 Fs(3)Zer Female sterile (3) Zerind http://flybase.net/reports/FBgn0001071.html gene 0007126=meiotic nuclear division "Fs(3)Sz25, Fs(3)Zerind, Zer" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,meiotic cell cycle defective" "female pronucleus | maternal effect,pronucleus | maternal effect" FBgn0011104 l(1)Q65 lethal (1) Q65 http://flybase.net/reports/FBgn0011104.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0020243 ziti ziti http://flybase.net/reports/FBgn0020243.html gene 0048477=oogenesis 16-Dec-15 2015_12 FBgn0019637 Atu Another transcription unit http://flybase.net/reports/FBgn0019637.html FBgn0011015 protein_coding_gene "0035206=regulation of hemocyte proliferation, 0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter" 0016593=Cdc73/Paf1 complex "CG1433, l(3)s1938" IPR007149=Leo1-like protein CG1433 16-Dec-15 2015_12 ENSDARG00000055357(leo1) YOR123C(LEO1) WBGene00007110(B0035.11) ENSXETG00000020746(LEO1) ENSMUSG00000042487(Leo1) ENSG00000166477(LEO1) "lethal,recessive,viable,body color defective" mesothoracic tergum FBgn0030196 Psf3 Psf3 http://flybase.net/reports/FBgn0030196.html protein_coding_gene 0043138=3'-5' DNA helicase activity "0022008=neurogenesis, 0046331=lateral inhibition" 0000811=GINS complex CG2222 "IPR021151=GINS complex, IPR010492=GINS complex, subunit Psf3" CG2222 16-Dec-15 2015_12 ENSDARG00000038847(gins3) ENSXETG00000013741(GINS3) ENSMUSG00000031669(Gins3) ENSG00000181938(GINS3) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0032194 CG4901 http://flybase.net/reports/FBgn0032194.html protein_coding_gene "0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0003676=nucleic acid binding, 0004386=helicase activity" "0022008=neurogenesis, 0000390=spliceosomal complex disassembly" 0005681=spliceosomal complex cg4901 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007502=Helicase-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011709=Domain of unknown function DUF1605, IPR011545=DEAD/DEAH box helicase domain, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650=Helicase, C-terminal" CG4901 16-Dec-15 2015_12 ENSDARG00000051785(LOC796505) ENSXETG00000009173(dhx33) ENSMUSG00000040620(Dhx33) ENSG00000005100(DHX33) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0040349 CG3699 http://flybase.net/reports/FBgn0040349.html FBgn0029549 protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors, 0008670=2,4-dienoyl-CoA reductase (NADPH) activity" "0008152=metabolic process, 0006635=fatty acid beta-oxidation" "EG:BACR7A4.14, CT12411" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase, IPR020904=Short-chain dehydrogenase/reductase, conserved site" CG3699 16-Dec-15 2015_12 "YIR035C(),YIR036C(IRC24)" ENSMUSG00000030825(Hsd17b14) ENSG00000087076(HSD17B14) viable FBgn0029762 NAAT1 Nutrient Amino Acid Transporter 1 http://flybase.net/reports/FBgn0029762.html FBgn0045954 protein_coding_gene "0042943=D-amino acid transmembrane transporter activity, 0015179=L-amino acid transmembrane transporter activity, 0015175=neutral amino acid transmembrane transporter activity, 0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity, 0017032=potassium:amino acid symporter activity, 0005416=cation:amino acid symporter activity" "0015807=L-amino acid transport, 0006836=neurotransmitter transport, 0042940=D-amino acid transport, 0044745=amino acid transmembrane import, 0006814=sodium ion transport, 0015804=neutral amino acid transport" 0016021=integral component of membrane "anon-WO0149848.3, DmNAT1, dmNAT1, CG3252" IPR000175=Sodium:neurotransmitter symporter CG3252 16-Dec-15 2015_12 viable FBgn0264998 CR44149 http://flybase.net/reports/FBgn0264998.html non_protein_coding_gene lincRNA.91 CR44149 16-Dec-15 2015_12 FBgn0031520 CG8837 http://flybase.net/reports/FBgn0031520.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG8837 16-Dec-15 2015_12 viable FBgn0035645 CG5592 http://flybase.net/reports/FBgn0035645.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like, IPR011701=Major facilitator superfamily" CG5592 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "partially lethal - majority die,some die during pupal stage" FBgn0266523 CG9940::Mmus\Ube4b http://flybase.net/reports/FBgn0266523.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0065459 l(2)SH1382 lethal (2) SH1382 http://flybase.net/reports/FBgn0065459.html gene l(2)SH2 1382 16-Dec-15 2015_12 "lethal,recessive" FBgn0037004 CG17637 http://flybase.net/reports/FBgn0037004.html protein_coding_gene 0015144=carbohydrate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR001958=Tetracycline resistance protein, TetA/multidrug resistance protein MdtG, IPR011701=Major facilitator superfamily" CG17637 16-Dec-15 2015_12 FBgn0034540 Lrt Leucine-rich tendon-specific protein http://flybase.net/reports/FBgn0034540.html protein_coding_gene 0005515=protein binding "2001283=Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell, 2001282=negative regulation of muscle cell chemotaxis toward tendon cell" "0005886=plasma membrane, 0016021=integral component of membrane, 0005927=muscle tendon junction, 0043234=protein complex" "CG11136, CT31131, lrt, tartan/capricious-like, Leucine-rich tendon-specific protein" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG11136 16-Dec-15 2015_12 "ENSXETG00000004288(SLITRK2),ENSXETG00000023987(SLITRK5),ENSXETG00000012352(SLITRK4),ENSXETG00000013354(SLITRK1)" viable "ventral longitudinal muscle,embryonic/larval somatic muscle,A1-7 ventral oblique muscle 4,A1-7 ventral acute muscle 3" DRSC06045 E -0.790561286 0.424615961 -0.107030463 1.665103435 -0.043728304 0.44673536 FBgn0262315 mir-2493 mir-2493 stem loop http://flybase.net/reports/FBgn0262315.html miRNA_gene "CR43022, dme-miR-2493-5p, dme-mir-2493" CR43022 16-Dec-15 2015_12 viable FBgn0036998 CG5969 http://flybase.net/reports/FBgn0036998.html "FBgn0047096, FBgn0052426, FBgn0062477" protein_coding_gene 0070072=vacuolar proton-transporting V-type ATPase complex assembly "CG32426, BcDNA:RE53796, BcDNA:GM09417" IPR019013=Vacuolar ATPase assembly integral membrane protein Vma21 CG5969 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0085202 CG34173 http://flybase.net/reports/FBgn0085202.html protein_coding_gene CG34173 16-Dec-15 2015_12 FBgn0262979 CR43287 http://flybase.net/reports/FBgn0262979.html non_protein_coding_gene CG43287 CR43287 16-Dec-15 2015_12 FBgn0029740 CG12680 http://flybase.net/reports/FBgn0029740.html protein_coding_gene CG12680 16-Dec-15 2015_12 viable FBgn0264395 CG43843 http://flybase.net/reports/FBgn0264395.html FBgn0030923 protein_coding_gene CG15049 CG43843 16-Dec-15 2015_12 FBgn0004524 l(4)102EFa lethal (4) 102EFa http://flybase.net/reports/FBgn0004524.html gene "l(4)9, l(4)1-JFC, l(4)BU-1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002043 l(2)37Dg lethal (2) 37Dg http://flybase.net/reports/FBgn0002043.html gene l(2)OE39 16-Dec-15 2015_12 lethal FBgn0037093 Cdk12 Cyclin-dependent kinase 12 http://flybase.net/reports/FBgn0037093.html "FBgn0043014, FBgn0044713" protein_coding_gene "0008353=RNA polymerase II carboxy-terminal domain kinase activity, 0005524=ATP binding, 0004693=cyclin-dependent protein serine/threonine kinase activity" "0022008=neurogenesis, 0006909=phagocytosis, 0090277=positive regulation of peptide hormone secretion, 0046579=positive regulation of Ras protein signal transduction, 0040018=positive regulation of multicellular organism growth, 0006468=protein phosphorylation, 0070374=positive regulation of ERK1 and ERK2 cascade" "0005703=polytene chromosome puff, 0005700=polytene chromosome" "anon-WO0140519.165, CG7597, cg7597, gi24668141, AC017581, dCDK12" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG7597 16-Dec-15 2015_12 ENSDARG00000063726 YKL139W(CTK1) WBGene00007135(cdtl-7) "ENSXETG00000023695(CRKRS),ENSXETG00000013107(CDC2L5)" "ENSMUSG00000041297(Cdk13),ENSMUSG00000003119(Cdk12)" "ENSG00000065883(CDK13),ENSG00000167258(CDK12)" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC11836 I -2.145831887 3.612852403 1.160552934 -0.263228052 -0.605919049 -0.430251493 FBgn0034198 CG11400 http://flybase.net/reports/FBgn0034198.html protein_coding_gene CG11400 16-Dec-15 2015_12 FBgn0086901 cv-c crossveinless c http://flybase.net/reports/FBgn0086901.html "FBgn0086696, FBgn0010910, FBgn0051319, FBgn0040560, FBgn0038227, FBgn0038228, FBgn0051330, FBgn0000397, FBgn0038231, FBgn0038232, FBgn0085418, FBgn0038226" protein_coding_gene "0005096=GTPase activator activity, 0008289=lipid binding" "0033109=cortical actin cytoskeleton stabilization, 0008586=imaginal disc-derived wing vein morphogenesis, 0007274=neuromuscular synaptic transmission, 0007427=epithelial cell migration, open tracheal system, 0007443=Malpighian tubule morphogenesis, 0007173=epidermal growth factor receptor signaling pathway, 0048814=regulation of dendrite morphogenesis, 0008258=head involution, 0007494=midgut development, 0007391=dorsal closure, 0035277=spiracle morphogenesis, open tracheal system, 0035160=maintenance of epithelial integrity, open tracheal system, 0007424=open tracheal system development, 0007266=Rho protein signal transduction, 0035024=negative regulation of Rho protein signal transduction" "0016323=basolateral plasma membrane, 0005938=cell cortex" "CG14845, CG14849, rhoGAP88C, l(3)06951, lethal (3) 06951, CG31330, Cv-c, CG8480, CG34389, CG31319, CG14848, Crossveinless-c, CG14847, CG14846, RhoGAP88C, crossveinless-c" "IPR000198=Rho GTPase-activating protein domain, IPR013761=Sterile alpha motif/pointed domain, IPR008936=Rho GTPase activation protein, IPR002913=START domain, IPR023393=START-like domain" CG34389 16-Dec-15 2015_12 WBGene00001559(gei-1) FBgn0065794 l(2)SH0419 lethal (2) SH0419 http://flybase.net/reports/FBgn0065794.html gene l(2)SH2 0419 16-Dec-15 2015_12 "lethal,recessive" FBgn0065184 l(3)06142b lethal (3) 06142b http://flybase.net/reports/FBgn0065184.html FBgn0010882 gene l(3)06142 16-Dec-15 2015_12 "lethal,recessive" FBgn0053688 CG33688 http://flybase.net/reports/FBgn0053688.html protein_coding_gene 0046331=lateral inhibition IPR010512=Protein of unknown function DUF1091 CG33688 16-Dec-15 2015_12 "viable,visible" chaeta FBgn0043848 412\ORF2 ORF2 http://flybase.net/reports/FBgn0043848.html transposable_element_gene ORF2 16-Dec-15 2015_12 FBgn0085493 CG40506 http://flybase.net/reports/FBgn0085493.html FBan0040506 protein_coding_gene 16-Dec-15 2015_12 FBgn0082636 S(CycEJP)1S3 S(CycEJP)1S3 http://flybase.net/reports/FBgn0082636.html gene 1S3 16-Dec-15 2015_12 "lethal,recessive" FBgn0043064 Tehao::Tl Tehao::Tl http://flybase.net/reports/FBgn0043064.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0014993 l(3)90DEa lethal (3) 90DEa http://flybase.net/reports/FBgn0014993.html gene l(3)5D4 16-Dec-15 2015_12 "lethal,recessive" FBgn0015969 l(2)55Da lethal (2) 55Da http://flybase.net/reports/FBgn0015969.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025782 anon-MMS91 anon-MMS91 http://flybase.net/reports/FBgn0025782.html gene 16-Dec-15 2015_12 FBgn0265256 CG44270 http://flybase.net/reports/FBgn0265256.html protein_coding_gene lincRNA.207 CG44270 16-Dec-15 2015_12 FBgn0027509 TBCD tubulin folding cofactor D http://flybase.net/reports/FBgn0027509.html protein_coding_gene "0048487=beta-tubulin binding, 0005096=GTPase activator activity" "0048813=dendrite morphogenesis, 0006457=protein folding, 0007409=axonogenesis, 0031115=negative regulation of microtubule polymerization, 0000226=microtubule cytoskeleton organization, 0043547=positive regulation of GTPase activity" "CG7261, BcDNA:LD22320" "IPR022577=Tubulin-specific chaperone D, C-terminal, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG7261 16-Dec-15 2015_12 YOR349W(CIN1) WBGene00008887(F16D3.4) ENSMUSG00000039230(Tbcd) ENSG00000141556(TBCD) "viable,visible" trichogen cell FBgn0035031 CG13587 http://flybase.net/reports/FBgn0035031.html protein_coding_gene "IPR016186=C-type lectin-like, IPR001304=C-type lectin, IPR016187=C-type lectin fold" CG13587 16-Dec-15 2015_12 viable FBgn0267069 CR45513 http://flybase.net/reports/FBgn0267069.html non_protein_coding_gene CR45513 16-Dec-15 2015_12 FBgn0034570 CG10543 http://flybase.net/reports/FBgn0034570.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0042332=gravitaxis "IPR027124=SWR1-complex protein 5/Craniofacial development protein, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG10543 16-Dec-15 2015_12 "gravitaxis defective,viable" FBgn0011172 l(1)291-9 lethal (1) 291-9 http://flybase.net/reports/FBgn0011172.html FBgn0010199 gene 291-9 16-Dec-15 2015_12 "lethal,recessive" FBgn0085622 CG41336 http://flybase.net/reports/FBgn0085622.html FBan0041336 protein_coding_gene 16-Dec-15 2015_12 FBgn0034739 CG3927 http://flybase.net/reports/FBgn0034739.html FBgn0061443 protein_coding_gene 0003723=RNA binding 0046331=lateral inhibition 0016607=nuclear speck "BcDNA:AT29209, cg3927" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG3927 16-Dec-15 2015_12 WBGene00022101(Y69A2AR.32) "male fertile,viable,fertile,visible" "chaeta,trichogen cell,supernumerary,tormogen cell" DRSC04433 K -0.088671866 0.721271406 -0.180078422 -0.129856307 0.808576664 -1.84220885 FBgn0039698 CG7789 http://flybase.net/reports/FBgn0039698.html protein_coding_gene "0008441=3'(2'),5'-bisphosphate nucleotidase activity" 0046854=phosphatidylinositol phosphorylation "IPR020550=Inositol monophosphatase, conserved site, IPR000760=Inositol monophosphatase, IPR020583=Inositol monophosphatase, metal-binding site" CG7789 16-Dec-15 2015_12 ENSDARG00000043684(bpnt1) WBGene00044063(tag-231) ENSXETG00000002725(BPNT1) ENSMUSG00000026617(Bpnt1) ENSG00000162813(BPNT1) FBgn0053270 CG33270 http://flybase.net/reports/FBgn0053270.html "FBgn0036175, FBgn0040819, FBgn0052084" protein_coding_gene 0046331=lateral inhibition "CG14139, CG32084, CG6100" CG33270 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC10584 K 1.879979195 1.062089543 FBgn0058270 CG40270 http://flybase.net/reports/FBgn0058270.html FBan0040270 protein_coding_gene 16-Dec-15 2015_12 FBgn0264676 CR43961 http://flybase.net/reports/FBgn0264676.html non_protein_coding_gene CG43961 CR43961 16-Dec-15 2015_12 FBgn0266772 CR45237 http://flybase.net/reports/FBgn0266772.html non_protein_coding_gene CR45237 16-Dec-15 2015_12 FBgn0028523 CG5888 http://flybase.net/reports/FBgn0028523.html protein_coding_gene 0004888=transmembrane signaling receptor activity "CT18477, BG:DS02780.1" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG5888 16-Dec-15 2015_12 "viable,fertile" FBgn0051262 CG31262 http://flybase.net/reports/FBgn0051262.html protein_coding_gene 0005215=transporter activity "0006810=transport, 0055085=transmembrane transport" 0016020=membrane dSLC5A14 "IPR001734=Sodium/solute symporter, IPR019900=Sodium/solute symporter, subgroup" CG31262 16-Dec-15 2015_12 YHL016C(DUR3) DRSC13216 E -1.231515161 0.755300449 2.343924069 0.917808139 -0.487631205 -0.304477817 FBgn0034735 CG4610 http://flybase.net/reports/FBgn0034735.html protein_coding_gene 0050660=flavin adenine dinucleotide binding 0002098=tRNA wobble uridine modification "IPR026904=GidA associated domain 3, IPR004416=Glucose-inhibited division protein A, IPR002218=Glucose-inhibited division protein A-related, IPR020595=Glucose-inhibited division protein A-related, conserved site" CG4610 16-Dec-15 2015_12 ENSDARG00000055679(zgc:158782) YGL236C(MTO1) WBGene00009944(F52H3.2) ENSMUSG00000032342(Mto1) ENSG00000135297(MTO1) viable DRSC04477 K -0.943990332 0.139024208 -0.083137501 0.79969315 1.618695336 0.119877691 FBgn0010727 l(3)00720 lethal (3) 00720 http://flybase.net/reports/FBgn0010727.html gene "P720, unnamed" 16-Dec-15 2015_12 "lethal,recessive" FBgn0031869 CG18304 http://flybase.net/reports/FBgn0031869.html FBgn0031870 protein_coding_gene 0010506=regulation of autophagy 0005615=extracellular space CG13774 IPR027881=Protein SOGA CG18304 16-Dec-15 2015_12 WBGene00044079(tag-241) "ENSG00000149639(KIAA0889),ENSG00000168502(CCDC165)" viable FBgn0027629 ms(1)RA20 ms(1)RA20 http://flybase.net/reports/FBgn0027629.html gene 16-Dec-15 2015_12 male sterile spermatocyte FBgn0266770 CR45235 http://flybase.net/reports/FBgn0266770.html non_protein_coding_gene CR45235 16-Dec-15 2015_12 FBgn0261987 Pxt Peroxinectin-like http://flybase.net/reports/FBgn0261987.html "FBgn0038538, FBgn0046466, FBgn0026186" protein_coding_gene "0004601=peroxidase activity, 0020037=heme binding, 0004666=prostaglandin-endoperoxide synthase activity" "0001516=prostaglandin biosynthetic process, 0042743=hydrogen peroxide metabolic process, 0006979=response to oxidative stress, 0007306=eggshell chorion assembly, 0030707=ovarian follicle cell development, 0007304=chorion-containing eggshell formation, 0055114=oxidation-reduction process" 0005875=microtubule associated complex "anon-WO0172774.128, pxt, CG7660, unnamed, Dpxt, pxd" "IPR029590=Chorion peroxidase, IPR019791=Haem peroxidase, animal, IPR010255=Haem peroxidase" CG7660 16-Dec-15 2015_12 "WBGene00022743(mlt-7),WBGene00017968(F32A5.2)" FBgn0085489 CG34460 http://flybase.net/reports/FBgn0085489.html "FBan0006301, FBgn0034161" protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis 0005615=extracellular space "bs26g12, CG6301, bs26g12.y1" IPR029277=Single domain Von Willebrand factor type C domain CG34460 16-Dec-15 2015_12 FBgn0051506 tRNA:CR31506 transfer RNA:CR31506 http://flybase.net/reports/FBgn0051506.html FBgn0060150 tRNA_gene 0033403=UUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31506, AE002708.trna40-LeuTAA, chr3R.trna46-LeuTAA, tRNA:L:TAA:AE002708-c" CR31506 16-Dec-15 2015_12 FBgn0263513 mir-4953 mir-4953 stem loop http://flybase.net/reports/FBgn0263513.html miRNA_gene "CR43616, dme-mir-4953" CR43616 16-Dec-15 2015_12 FBgn0265345 CR44299 http://flybase.net/reports/FBgn0265345.html non_protein_coding_gene CG44299 CR44299 16-Dec-15 2015_12 FBgn0265364 CR44305 http://flybase.net/reports/FBgn0265364.html non_protein_coding_gene CR44305 16-Dec-15 2015_12 FBgn0082359 HM165 HM165 http://flybase.net/reports/FBgn0082359.html gene 16-Dec-15 2015_12 FBgn0066114 GlcAT-I GlcAT-I http://flybase.net/reports/FBgn0066114.html "FBgn0026081, FBgn0047321, FBgn0052775" protein_coding_gene "0015018=galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity, 0015020=glucuronosyltransferase activity" "0030166=proteoglycan biosynthetic process, 0015012=heparan sulfate proteoglycan biosynthetic process, 0030206=chondroitin sulfate biosynthetic process" "0016020=membrane, 0005886=plasma membrane" "DmGlcAT-I, dGlcAT-I, CAA21824, CG32775, DGlcAT-I, BcDNA:GH05057, RE38067, GH05057p, GlcAT1, EG:EG0007.5" "IPR005027=Glycosyl transferase, family 43, IPR029044=Nucleotide-diphospho-sugar transferases" CG32775 16-Dec-15 2015_12 "ENSDARG00000001939(b3gat3),ENSDARG00000030733(b3gat3)" WBGene00005026(sqv-8) "ENSXETG00000005581(Q599K4_XENTR),ENSXETG00000008325(B3GAT1)" ENSMUSG00000071649(B3gat3) ENSG00000149541(B3GAT3) embryonic stage -- adult stage "viable,fertile" FBgn0060584 l(3)S094405b lethal (3) S094405b http://flybase.net/reports/FBgn0060584.html gene 0944/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0010821 l(3)03847 lethal (3) 03847 http://flybase.net/reports/FBgn0010821.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011959 tRNA:R2:84Fa transfer RNA:arg2:84Fa http://flybase.net/reports/FBgn0011959.html "FBgn0003758, FBgn0011947, FBgn0051581, FBgn0060097" tRNA_gene "0033429=CGU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:R1, transfer RNA:arg1, tRNA:arg1, AE002708.trna62-ArgACG, tRNA[Arg][[2]], chr3R.trna68-ArgACG, CR31581, tRNA:R:ACG:AE002708-a, tRNA[arg], tRNA:arg2:84Fa" CR31581 16-Dec-15 2015_12 FBgn0002002 l(2)36Ba lethal (2) 36Ba http://flybase.net/reports/FBgn0002002.html FBgn0010489 gene "l(2L)HT-4, l(2)HT-4, l(2)01433" 16-Dec-15 2015_12 "lethal,recessive" FBgn0053370 5SrRNA:CR33370 5SrRNA:CR33370 http://flybase.net/reports/FBgn0053370.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33370 CR33370 16-Dec-15 2015_12 FBgn0053441 5SrRNA:CR33441 5SrRNA:CR33441 http://flybase.net/reports/FBgn0053441.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33441 CR33441 16-Dec-15 2015_12 FBgn0277427 l(3)psg20 http://flybase.net/reports/FBgn0277427.html gene psg20 16-Dec-15 2015_12 FBgn0022266 l(2)k00609 lethal (2) k00609 http://flybase.net/reports/FBgn0022266.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020283 l(3)10532 lethal (3) 10532 http://flybase.net/reports/FBgn0020283.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0004685 l(1)Mc51 lethal (1) Mc51 http://flybase.net/reports/FBgn0004685.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,wing hair" FBgn0024307 SS3-1 Suppressor of GMR-sina 3-1 http://flybase.net/reports/FBgn0024307.html gene 16-Dec-15 2015_12 FBgn0070009 BG01367 BG01367 http://flybase.net/reports/FBgn0070009.html gene 16-Dec-15 2015_12 stress response defective FBgn0016829 l(1)MZ16 lethal (1) MZ16 http://flybase.net/reports/FBgn0016829.html gene M16 16-Dec-15 2015_12 "lethal,recessive" FBgn0030162 CG1986 http://flybase.net/reports/FBgn0030162.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG1986 16-Dec-15 2015_12 FBgn0060850 l(3)S048518 lethal (3) S048518 http://flybase.net/reports/FBgn0060850.html gene 0485/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0040932 CG12650 http://flybase.net/reports/FBgn0040932.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036568 ATPsynë_L "ATP synthase, ë_ subunit-like" http://flybase.net/reports/FBgn0036568.html protein_coding_gene "0005524=ATP binding, 0046933=proton-transporting ATP synthase activity, rotational mechanism, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0010155=regulation of proton transport, 0015986=ATP synthesis coupled proton transport, 0015992=proton transport, 0048515=spermatid differentiation, 0008340=determination of adult lifespan, 0015991=ATP hydrolysis coupled proton transport" "0005811=lipid particle, 0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)" "male sterile (3) 72Dt, CG5389, ATP synthase Beta chain, ATPB, ms(3)72Dt, ATP synthase beta chain" "IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal, IPR005722=ATPase, F1 complex, beta subunit, IPR024034=ATPase, F1 complex beta subunit/V1 complex, C-terminal, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR003593=AAA+ ATPase domain, IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain" CG5389 16-Dec-15 2015_12 "male sterile,long lived,female,RU486 conditional,female semi-fertile,short lived,calorie restriction conditional,viable,fertile" FBgn0020347 anon-47Ea anon-47Ea http://flybase.net/reports/FBgn0020347.html gene 528 16-Dec-15 2015_12 FBgn0034859 CG3520 http://flybase.net/reports/FBgn0034859.html protein_coding_gene "IPR022542=Domain of unknown function DUF3730, IPR016024=Armadillo-type fold, IPR021392=Focadhesin" CG3520 16-Dec-15 2015_12 ENSDARG00000069666 ENSXETG00000015484() ENSMUSG00000038368(BC057079) ENSG00000188352(KIAA1797) "viable,fertile" FBgn0005554 l(3)85Fg lethal (3) 85Fg http://flybase.net/reports/FBgn0005554.html gene 16-Dec-15 2015_12 lethal FBgn0027343 fz3 frizzled 3 http://flybase.net/reports/FBgn0027343.html FBgn0025619 protein_coding_gene "0042813=Wnt-activated receptor activity, 0000166=nucleotide binding, 0004888=transmembrane signaling receptor activity, 0003676=nucleic acid binding, 0017147=Wnt-protein binding" "0016055=Wnt signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0007163=establishment or maintenance of cell polarity, 0007165=signal transduction" "0016021=integral component of membrane, 0016020=membrane" "Fz3, dFz3, CG16785, DFz3, dfz3, EG:34F3.6, dFrizzled3, Dm Fz3, Dfz3, frizzled3, Dfrizzled-3, Frizzled 3" "IPR026554=Frizzled-3, invertebrates, IPR015526=Frizzled/secreted frizzled-related protein, IPR000504=RNA recognition motif domain, IPR000539=Frizzled protein, IPR017981=GPCR, family 2-like, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR020067=Frizzled domain" CG16785 16-Dec-15 2015_12 larval stage | third instar " dorsal mesothoracic disc | restricted

, ventral thoracic disc | resticted

, eye-antennal disc | resticted

" "viable,fertile" FBgn0005525 l(2)52ACb lethal (2) 52ACb http://flybase.net/reports/FBgn0005525.html gene unnamed 16-Dec-15 2015_12 FBgn0036076 CG10427 http://flybase.net/reports/FBgn0036076.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025166 l(2)38EFe lethal (2) 38EFe http://flybase.net/reports/FBgn0025166.html gene 16-Dec-15 2015_12 "viable,fertile,lethal,recessive" FBgn0062575 Mod(var)E1178 Mod(var)E1178 http://flybase.net/reports/FBgn0062575.html gene 0006342=chromatin silencing E1178 16-Dec-15 2015_12 "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0058442 CG40442 http://flybase.net/reports/FBgn0058442.html protein_coding_gene 16-Dec-15 2015_12 FBgn0041167 anon-A6 anon-A6 http://flybase.net/reports/FBgn0041167.html gene A6 16-Dec-15 2015_12 FBgn0051236 CG31236 http://flybase.net/reports/FBgn0051236.html FBgn0047294 protein_coding_gene BcDNA:GM01352 16-Dec-15 2015_12 FBgn0264901 CR44092 http://flybase.net/reports/FBgn0264901.html non_protein_coding_gene CR44092 16-Dec-15 2015_12 FBgn0083097 bi::org-1 bi::org-1 http://flybase.net/reports/FBgn0083097.html engineered_fusion_gene 16-Dec-15 2015_12 "eye,arista,leg,ectopic,ommatidium,microchaeta,interommatidial bristle" FBgn0040102 lectin-24Db lectin-24Db http://flybase.net/reports/FBgn0040102.html FBgn0031588 protein_coding_gene "0005537=mannose binding, 0042806=fucose binding, 0030246=carbohydrate binding, 0005534=galactose binding" "AC 004371A, CG2958, AC004371a, Lectin24DB, Lectin-24Db, lectin, Lectin24Db" "IPR016186=C-type lectin-like, IPR001304=C-type lectin, IPR016187=C-type lectin fold" CG2958 16-Dec-15 2015_12 ENSDARG00000013266(colec11) WBGene00019328(clec-149) "ENSXETG00000012694(CLEC3A),ENSXETG00000020143(BC088053.1)" "ENSMUSG00000040963(Asgr2),ENSMUSG00000020884(Asgr1),ENSMUSG00000000318(Clec10a),ENSMUSG00000040950(Mgl2),ENSMUSG00000036103(Colec12),ENSMUSG00000034783(Cd207)" ENSG00000166509(CLEC3A) viable FBgn0003873 Tu Turned-up wing http://flybase.net/reports/FBgn0003873.html gene 16-Dec-15 2015_12 "visible,viable" wing FBgn0065892 l(2)SH0217 lethal (2) SH0217 http://flybase.net/reports/FBgn0065892.html gene l(2)SH2 0217 16-Dec-15 2015_12 "lethal,recessive" FBgn0061494 l(3)18304 lethal (3) 18304 http://flybase.net/reports/FBgn0061494.html gene "0007319=negative regulation of oskar mRNA translation, 0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal,recessive" "embryonic head,germline clone,maternal effect,embryonic thorax,embryonic abdomen,ectopic" FBgn0034554 CG15227 http://flybase.net/reports/FBgn0034554.html protein_coding_gene 0004089=carbonate dehydratase activity "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class" CG15227 16-Dec-15 2015_12 FBgn0024578 l(3)rL203 lethal (3) rL203 http://flybase.net/reports/FBgn0024578.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065084 snmRNA:763 small non-messenger RNA 763 http://flybase.net/reports/FBgn0065084.html FBgn0053711 non_protein_coding_gene "Dm-763, CR33711" CR33711 16-Dec-15 2015_12 FBgn0035056 spz6 spatzle 6 http://flybase.net/reports/FBgn0035056.html FBgn0063087 protein_coding_gene 0005121=Toll binding 0008063=Toll signaling pathway 0005576=extracellular region "CG9196, CT26280, BcDNA:LP10725, Spz6" IPR029034=Cystine-knot cytokine CG9196 16-Dec-15 2015_12 "viable,fertile" FBgn0040248 anon-49Db anon-49Db http://flybase.net/reports/FBgn0040248.html gene 0005544=calcium-dependent phospholipid binding 11A 16-Dec-15 2015_12 FBgn0085641 CG41395 http://flybase.net/reports/FBgn0085641.html FBan0041395 protein_coding_gene 16-Dec-15 2015_12 FBgn0267049 CG45493 http://flybase.net/reports/FBgn0267049.html protein_coding_gene CG45493 16-Dec-15 2015_12 FBgn0067311 CheB38b Chemosensory protein B 38b http://flybase.net/reports/FBgn0067311.html "FBgn0032887, FBgn0053321" protein_coding_gene 0008289=lipid binding "0007606=sensory perception of chemical stimulus, 0043695=detection of pheromone" "0005615=extracellular space, 0005576=extracellular region" "CheB38b, CG9329, CG33321, 38E.23" "IPR010512=Protein of unknown function DUF1091, IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG33321 16-Dec-15 2015_12 viable FBgn0038054 CG5509 http://flybase.net/reports/FBgn0038054.html protein_coding_gene CG5509 16-Dec-15 2015_12 viable FBgn0267604 CR45942 http://flybase.net/reports/FBgn0267604.html non_protein_coding_gene CR45942 16-Dec-15 2015_12 FBgn0053191 CG33191 http://flybase.net/reports/FBgn0053191.html "FBgn0044568, FBgn0045762, FBgn0045836" protein_coding_gene "BcDNA:GH01761, anon-WO0140519.60, BEST:GH01761" CG33191 16-Dec-15 2015_12 viable FBgn0037227 TwdlV TweedleV http://flybase.net/reports/FBgn0037227.html FBan0014640 protein_coding_gene 0005214=structural constituent of chitin-based cuticle 0040003=chitin-based cuticle development 0005578=proteinaceous extracellular matrix "CG14640, Tweedle V" IPR004145=Domain of unknown function DUF243 CG14640 16-Dec-15 2015_12 FBgn0037185 CG11367 http://flybase.net/reports/FBgn0037185.html FBgn0052454 protein_coding_gene 0016021=integral component of membrane IPR015414=Transmembrane protein Tvp38/TMEM64-like CG11367 16-Dec-15 2015_12 ENSDARG00000061723(si:dkeyp-34f6.5) YKR088C(TVP38) ENSXETG00000014606(TMEM64) ENSMUSG00000043252(Tmem64) ENSG00000180694(TMEM64) "viable,fertile" FBgn0037213 CG12581 http://flybase.net/reports/FBgn0037213.html protein_coding_gene IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) CG12581 16-Dec-15 2015_12 WBGene00020104(R148.5) "visible,partially lethal - majority die,some die during pupal stage,viable,body color defective" "trichogen cell,chaeta,supernumerary,mesothoracic tergum" FBgn0037698 CG16779 http://flybase.net/reports/FBgn0037698.html protein_coding_gene "0046872=metal ion binding, 0003677=DNA binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR000949=ELM2 domain, IPR009057=Homeodomain-like, IPR007087=Zinc finger, C2H2, IPR017884=SANT domain, IPR015880=Zinc finger, C2H2-like, IPR001005=SANT/Myb domain" CG16779 16-Dec-15 2015_12 "ENSMUSG00000064043(Trerf1),ENSMUSG00000042507(C130039O16Rik)" "ENSG00000124496(TRERF1),ENSG00000156030(C14orf43)" viable DRSC15153 K -0.330473416 -1.147200459 0.047791599 -1.104240657 -1.326210351 -3.034568446 FBgn0262708 ifm(2)RS1 http://flybase.net/reports/FBgn0262708.html gene "0060361=flight, 0007527=adult somatic muscle development" 16-Dec-15 2015_12 "flightless,recessive" dorsal medial muscle FBgn0036089 CG14151 http://flybase.net/reports/FBgn0036089.html protein_coding_gene CG14151 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum DRSC10153 E 0.056923002 -1.327908386 2.299723351 -0.242262893 0.933765552 0.178061266 FBgn0031765 CG9109 http://flybase.net/reports/FBgn0031765.html "FBtr0079224, FBpp0078855" protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" 0016020=membrane dC1GalT9 IPR003378=Fringe-like CG9109 16-Dec-15 2015_12 WBGene00022576(ZC250.2) ENSXETG00000019184(B3GALTL) ENSMUSG00000051950(B3galtl) ENSG00000187676(B3GALTL) "lethal,body color defective" mesothoracic tergum FBgn0259465 C495 http://flybase.net/reports/FBgn0259465.html gene 16-Dec-15 2015_12 visible "wing vein,wing vein L4" FBgn0039296 CG10420 http://flybase.net/reports/FBgn0039296.html protein_coding_gene "0006616=SRP-dependent cotranslational protein targeting to membrane, translocation" "0012505=endomembrane system, 0005783=endoplasmic reticulum" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG10420 16-Dec-15 2015_12 ENSXETG00000000959(SIL1) ENSMUSG00000024357(Sil1) ENSG00000120725(SIL1) viable DRSC14242 E 0.528342786 0.257767637 1.952200948 1.30461057 -0.426873822 0.774138065 FBgn0063419 l(3)3450-D lethal (3) 3450-D http://flybase.net/reports/FBgn0063419.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0062652 EP374 EP374 http://flybase.net/reports/FBgn0062652.html gene EP(3)0374 16-Dec-15 2015_12 visible "wing,scutellum,adult thorax,dorsal" FBgn0034583 CG10527 http://flybase.net/reports/FBgn0034583.html protein_coding_gene 0019010=farnesoic acid O-methyltransferase activity 0005737=cytoplasm "FAMeT, Farnesoic acid O-methyltransferase" "IPR024518=Domain of unknown function DUF3421, IPR022041=Farnesoic acid O-methyl transferase, IPR006616=DM9 repeat" CG10527 16-Dec-15 2015_12 "short lived,viable,chemical resistant" FBgn0061080 l(3)S014310b lethal (3) S014310b http://flybase.net/reports/FBgn0061080.html gene 0143/10 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003905 ty tiny http://flybase.net/reports/FBgn0003905.html gene 0048477=oogenesis l(1)4-103 16-Dec-15 2015_12 "lethal,recessive,visible,female sterile" "macrochaeta & thorax,eye" FBgn0259753 ms(2)Fra-4 http://flybase.net/reports/FBgn0259753.html gene "0051276=chromosome organization, 0007283=spermatogenesis" 16-Dec-15 2015_12 male sterile "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,spermatozoon" FBgn0034911 CG5549 http://flybase.net/reports/FBgn0034911.html protein_coding_gene "0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity, 0015375=glycine:sodium symporter activity" "0015816=glycine transport, 0006836=neurotransmitter transport" 0016021=integral component of membrane IPR000175=Sodium:neurotransmitter symporter CG5549 16-Dec-15 2015_12 "ENSDARG00000015880(slc6a5),ENSDARG00000067964,ENSDARG00000018534(slc6a9)" ENSXETG00000003268(SLC6A9) "ENSMUSG00000031089(Slc6a14),ENSMUSG00000039728(Slc6a5)" "ENSG00000087916(SLC6A14),ENSG00000165970(SLC6A5)" "viable,visible" trichogen cell FBgn0027136 l(3)88EFa lethal (3) 88EFa http://flybase.net/reports/FBgn0027136.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0020895 Su(osk)G71 Suppressor of oskar G71 http://flybase.net/reports/FBgn0020895.html gene G71 16-Dec-15 2015_12 FBgn0069423 JJF028 JJF028 http://flybase.net/reports/FBgn0069423.html gene 16-Dec-15 2015_12 stress response defective FBgn0035358 CG14949 http://flybase.net/reports/FBgn0035358.html protein_coding_gene CG14949 16-Dec-15 2015_12 FBgn0262025 CR42836 http://flybase.net/reports/FBgn0262025.html non_protein_coding_gene lincRNA.818 CR42836 16-Dec-15 2015_12 FBgn0024998 CG2685 http://flybase.net/reports/FBgn0024998.html protein_coding_gene 0044822=poly(A) RNA binding "0006396=RNA processing, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" EG:100G10.1 IPR019007=WW domain binding protein 11 CG2685 16-Dec-15 2015_12 ENSDARG00000017046(zgc:77390) WBGene00009364(F33H1.3) ENSXETG00000002770(wbp11) ENSMUSG00000030216(Wbp11) ENSG00000084463(WBP11) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC18463 E -1.496589167 -0.933106189 1.688498094 -1.846632426 0.961629419 1.147872764 FBgn0063391 snoRNA:U14:30Eb snoRNA:U14:30Eb http://flybase.net/reports/FBgn0063391.html snoRNA_gene 0030556=rRNA modification guide activity 0005730=nucleolus "snoRNA:U14:b, U14snoRNA, Dm-396, CR32876" CR32876 16-Dec-15 2015_12 FBgn0001458 l(1)7Dl lethal (1) 7Dl http://flybase.net/reports/FBgn0001458.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,egg,maternal effect" FBgn0082933 snoRNA:Me28S-G1083c snoRNA:Me28S-G1083c http://flybase.net/reports/FBgn0082933.html snoRNA_gene 0030562=rRNA 2'-O-ribose methylation guide activity 0000451=rRNA 2'-O-methylation 0005730=nucleolus "Me28S-Gm1083c, CR34564, DmSnR60c, DmSnR60" CR34564 16-Dec-15 2015_12 FBgn0266699 CR45189 http://flybase.net/reports/FBgn0266699.html non_protein_coding_gene CR45189 16-Dec-15 2015_12 FBgn0029582 CG3729 http://flybase.net/reports/FBgn0029582.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040545 CG14702 http://flybase.net/reports/FBgn0040545.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002640 mah mahogany http://flybase.net/reports/FBgn0002640.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0046667 anon-38C.3 anon-38C.3 http://flybase.net/reports/FBgn0046667.html gene 38C.3 16-Dec-15 2015_12 FBgn0000143 at arctus oculus http://flybase.net/reports/FBgn0000143.html gene "bar eye, arctops, bar-eye" 16-Dec-15 2015_12 "visible,recessive,viable,good,fertile" eye FBgn0051826 CG31826 http://flybase.net/reports/FBgn0051826.html FBgn0028843 protein_coding_gene 0005215=transporter activity 0006810=transport 0005622=intracellular "CG13241, BG:DS09217.6" "IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR011074=CRAL/TRIO, N-terminal domain" CG31826 16-Dec-15 2015_12 viable FBgn0263401 CG43447 http://flybase.net/reports/FBgn0263401.html protein_coding_gene lincRNA.869 CG43447 16-Dec-15 2015_12 FBgn0034838 CG12782 http://flybase.net/reports/FBgn0034838.html protein_coding_gene 0016973=poly(A)+ mRNA export from nucleus 0005634=nucleus "IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG12782 16-Dec-15 2015_12 viable FBgn0022810 E(faf)bE160 Enhancer of faf bE160 http://flybase.net/reports/FBgn0022810.html gene 16-Dec-15 2015_12 viable FBgn0264445 CR43863 http://flybase.net/reports/FBgn0264445.html non_protein_coding_gene CR43863 16-Dec-15 2015_12 FBgn0036993 CG5910 http://flybase.net/reports/FBgn0036993.html protein_coding_gene CK02563 CG5910 16-Dec-15 2015_12 "viable,fertile" FBgn0035121 Tudor-SN Tudor staphylococcal nuclease http://flybase.net/reports/FBgn0035121.html protein_coding_gene "0003713=transcription coactivator activity, 0004518=nuclease activity" 0035194=posttranscriptional gene silencing by RNA "0005829=cytosol, 0016442=RISC complex, 0005875=microtubule associated complex, 0005811=lipid particle" "dP100, TUDOR-SN, p100, tudor staphylococcal nuclease, TSN, SND1, Tudor-SN, CG7008, TSN-1, tudor-SN" "IPR002999=Tudor domain, IPR030481=Staphylococcal nuclease domain-containing protein 1, IPR016071=Staphylococcal nuclease (SNase-like), OB-fold, IPR016685=RNA-induced silencing complex, nuclease component Tudor-SN" CG7008 16-Dec-15 2015_12 ENSDARG00000006766(snd1) WBGene00006626(tsn-1) ENSXETG00000023043(snd1) ENSMUSG00000001424(Snd1) ENSG00000197157(SND1) "viable,fertile" FBgn0037566 mRpL1 mitochondrial ribosomal protein L1 http://flybase.net/reports/FBgn0037566.html protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" 0006412=translation 0005762=mitochondrial large ribosomal subunit "CG7494, L1" "IPR028364=Ribosomal protein L1/ribosomal biogenesis protein, IPR016094=Ribosomal protein L1, 2-layer alpha/beta-sandwich, IPR005879=Ribosomal protein L1, mitochondrial, IPR016095=Ribosomal protein L1, 3-layer alpha/beta-sandwich, IPR023674=Ribosomal protein L1-like" CG7494 16-Dec-15 2015_12 ENSDARG00000054606(si:dkey-58f10.1) WBGene00017997(F33D4.5) ENSXETG00000000373(Q4QQQ8_XENTR) ENSMUSG00000029486(Mrpl1) ENSG00000169288(MRPL1) "viable,fertile,visible" trichogen cell DRSC16251 I -1.85613842 -0.653112708 -0.926021638 -0.212620155 0.304789144 1.146192678 FBgn0069971 CG40496 http://flybase.net/reports/FBgn0069971.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024358 ES2-1 Enhancer of GMR-sina 2-1 http://flybase.net/reports/FBgn0024358.html gene 16-Dec-15 2015_12 FBgn0036732 Oatp74D Organic anion transporting polypeptide 74D http://flybase.net/reports/FBgn0036732.html protein_coding_gene "0008514=organic anion transmembrane transporter activity, 0015347=sodium-independent organic anion transmembrane transporter activity" "0015711=organic anion transport, 0006810=transport" 0016020=membrane "oatp 74D, CG7571" "IPR020846=Major facilitator superfamily domain, IPR002350=Kazal domain, IPR004156=Organic anion transporter polypeptide OATP" CG7571 16-Dec-15 2015_12 "WBGene00018568(F47E1.4),WBGene00018566(F47E1.2),WBGene00012531(Y32F6B.1)" "viable,visible" mesothoracic tergum FBgn0011952 tRNA:R:12Ee transfer RNA:arg:12Ee http://flybase.net/reports/FBgn0011952.html "FBgn0011947, FBgn0052624, FBgn0060083" tRNA_gene "0033431=CGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:R:TCG:AE002593-a, tRNA[arg], transfer RNA:arg1, tRNA:R1, CR32624, tRNA:arg1, chrX.trna5-ArgTCG, AE002593.trna1-ArgTCG, tRNA:arg12Ee, tRNA-Arg" CR32624 16-Dec-15 2015_12 FBgn0030124 CG12667 http://flybase.net/reports/FBgn0030124.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263572 mir-4981 mir-4981 stem loop http://flybase.net/reports/FBgn0263572.html miRNA_gene "dme-mir-4981, CR43557" CR43557 16-Dec-15 2015_12 FBgn0023446 dre dark red http://flybase.net/reports/FBgn0023446.html gene dr 16-Dec-15 2015_12 visible pigment cell FBgn0001676 l(1)EN13 lethal (1) from Eugene Nonautonomous 13 http://flybase.net/reports/FBgn0001676.html gene 16-Dec-15 2015_12 lethal FBgn0030806 CG13001 http://flybase.net/reports/FBgn0030806.html protein_coding_gene 0005515=protein binding 0007399=nervous system development "0005737=cytoplasm, 0005634=nucleus" "IPR018482=Zinc finger, C4H2-type" CG13001 16-Dec-15 2015_12 ENSDARG00000015314(zc4h2) WBGene00014152(ZK930.2) viable FBgn0065595 l(2)SH0892 lethal (2) SH0892 http://flybase.net/reports/FBgn0065595.html gene l(2)SH2 0892 16-Dec-15 2015_12 "lethal,recessive" FBgn0065815 l(2)SH0379 lethal (2) SH0379 http://flybase.net/reports/FBgn0065815.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260777 CG42571 http://flybase.net/reports/FBgn0260777.html protein_coding_gene chr3L.16.093a CG42571 16-Dec-15 2015_12 FBgn0013587 l(3)97Db lethal (3) 97Db http://flybase.net/reports/FBgn0013587.html gene l(3)155 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0045863 blood\sORF sORF http://flybase.net/reports/FBgn0045863.html transposable_element_gene 16-Dec-15 2015_12 FBgn0029118 Sucb Sucb http://flybase.net/reports/FBgn0029118.html FBgn0035614 protein_coding_gene "0005524=ATP binding, 0004776=succinate-CoA ligase (GDP-forming) activity" 0006099=tricarboxylic acid cycle "0005811=lipid particle, 0045244=succinate-CoA ligase complex (GDP-forming)" "sucB, CG10622, 142911_at, sucb" "IPR005809=Succinyl-CoA synthetase, beta subunit, IPR013816=ATP-grasp fold, subdomain 2, IPR013650=ATP-grasp fold, succinyl-CoA synthetase-type, IPR013815=ATP-grasp fold, subdomain 1, IPR016102=Succinyl-CoA synthetase-like, IPR005811=ATP-citrate lyase/succinyl-CoA ligase, IPR017866=Succinyl-CoA synthetase, beta subunit, conserved site" CG10622 16-Dec-15 2015_12 ENSDARG00000044914 WBGene00016844(C50F7.4) ENSXETG00000002522(suclg2) ENSMUSG00000061838(Suclg2) ENSG00000172340(SUCLG2) viable DRSC11294 K 1.405500056 0.080852975 0.703715679 -0.10521442 -0.050090907 1.520624111 FBgn0030930 GalNAc-T2 UDP-N-acetyl-ë±-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 http://flybase.net/reports/FBgn0030930.html FBgn0066048 protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process "0005795=Golgi stack, 0012505=endomembrane system" "polypeptide GalNAc transferase 7, pgant7, dGalNAc-T2, anon-WO02059370.15, CG6394, PGANT7" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain, IPR001173=Glycosyltransferase 2-like" CG6394 16-Dec-15 2015_12 ENSDARG00000057303(galnt7) WBGene00001632(gly-7) ENSXETG00000016917(galnt7) ENSMUSG00000031608(Galnt7) ENSG00000109586(GALNT7) "viable,fertile,lethal,partially lethal - majority die" FBgn0026441 ear ENL/AF9-related http://flybase.net/reports/FBgn0026441.html FBgn0038317 protein_coding_gene "0006367=transcription initiation from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" "0032783=ELL-EAF complex, 0005669=transcription factor TFIID complex, 0005674=transcription factor TFIIF complex" "CG4913, dENL/AF9, ENL/AF-9, Ear, ENL/AF9" IPR005033=YEATS CG4913 16-Dec-15 2015_12 "ENSDARG00000043185(LOC565484),ENSDARG00000031709(zgc:136639),ENSDARG00000006754(mllt3)" "ENSXETG00000021875(MLLT1),ENSXETG00000015500(mllt3)" "ENSMUSG00000028496(Mllt3),ENSMUSG00000024212(Mllt1)" "ENSG00000171843(MLLT3),ENSG00000130382(MLLT1)" viable DRSC15675 E 1.017548008 0.815218848 2.45208999 1.647138559 -1.044325768 -0.264757704 FBgn0065205 l(2)SH2280 lethal (2) SH2280 http://flybase.net/reports/FBgn0065205.html gene l(2)SH2 2280 16-Dec-15 2015_12 "lethal,recessive" FBgn0265821 CR44610 http://flybase.net/reports/FBgn0265821.html non_protein_coding_gene CR44610 16-Dec-15 2015_12 FBgn0015000 ë_ggt-I ë_ subunit of type I geranylgeranyl transferase http://flybase.net/reports/FBgn0015000.html protein_coding_gene "0004662=CAAX-protein geranylgeranyltransferase activity, 0004661=protein geranylgeranyltransferase activity" "0070374=positive regulation of ERK1 and ERK2 cascade, 0007265=Ras protein signal transduction, 0035050=embryonic heart tube development, 0046579=positive regulation of Ras protein signal transduction, 0022008=neurogenesis" "betaGGT-I, ggt-1, Suppressor of Ras1 2-2, beta GGT-I, SR2-2, betaGGTI, GGT1, beta-GGT, betaggt-I, type I Geranylgeranyl Transferase, bro3, CG3469, ggt1" "IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR001330=PFTB repeat" CG3469 16-Dec-15 2015_12 ENSDARG00000058613 WBGene00013002(Y48E1B.3) ENSXETG00000011296(pggt1b) ENSMUSG00000024477(Pggt1b) ENSG00000164219(PGGT1B) "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic pericardial cell,cardioblast,embryonic/larval neuroblast,ganglion mother cell" FBgn0041099 ppo poco pelo http://flybase.net/reports/FBgn0041099.html FBgn0043357 gene EP2478 16-Dec-15 2015_12 "visible,wild-type,recessive,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,microchaeta,thecogen cell,ectopic,tormogen cell,trichogen cell,wing margin,scutellum,wing margin bristle,supernumerary,somatic clone,adult thoracic sensillum" FBgn0001805 l(1)Mc35 lethal (1) Mc35 http://flybase.net/reports/FBgn0001805.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031045 CG14212 http://flybase.net/reports/FBgn0031045.html protein_coding_gene "0016462=pyrophosphatase activity, 0016791=phosphatase activity" 0008152=metabolic process "19527979, CG14122" "IPR016965=Phosphatase PHOSPHO-type, IPR023214=HAD-like domain, IPR006384=Pyridoxal phosphate phosphatase-related, IPR006383=HAD-superfamily hydrolase, subfamily IB, PSPase-like" CG14212 16-Dec-15 2015_12 "viable,fertile" FBgn0264551 CR43930 http://flybase.net/reports/FBgn0264551.html non_protein_coding_gene CR43930 16-Dec-15 2015_12 FBgn0002107 l(2)64 lethal (2) 64 http://flybase.net/reports/FBgn0002107.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082669 GS2143 GS2143 http://flybase.net/reports/FBgn0082669.html gene 16-Dec-15 2015_12 FBgn0027514 CG1024 http://flybase.net/reports/FBgn0027514.html protein_coding_gene 0046872=metal ion binding 0022008=neurogenesis BcDNA:LD21969 "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR022755=Zinc finger, double-stranded RNA binding" CG1024 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC12496 K 1.282010376 -0.715777293 1.405237754 -1.309526606 -2.017089235 -0.674651051 FBgn0035239 CG18170 http://flybase.net/reports/FBgn0035239.html "FBgn0052316, FBtr0072748, FBpp0072631, FBtr0072749, FBpp0072632, FBtr0072750, FBpp0072633, FBtr0072751, FBpp0072634, FBtr0072752, FBpp0072635, FBtr0072753, FBpp0072636" protein_coding_gene CG32316 CG18170 16-Dec-15 2015_12 FBgn0036791 CG7271 http://flybase.net/reports/FBgn0036791.html protein_coding_gene 0046872=metal ion binding "IPR007087=Zinc finger, C2H2" CG7271 16-Dec-15 2015_12 FBgn0250744 l(3)S139908 lethal (3) S139908 http://flybase.net/reports/FBgn0250744.html gene l(3)s139908 16-Dec-15 2015_12 lethal FBgn0067358 l(3)4106 lethal (3) 4106 http://flybase.net/reports/FBgn0067358.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020327 anon-72Da anon-72Da http://flybase.net/reports/FBgn0020327.html gene "unnamed, 5B3" 16-Dec-15 2015_12 FBgn0034712 CG3264 http://flybase.net/reports/FBgn0034712.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR018299=Alkaline phosphatase, active site, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase, IPR017850=Alkaline-phosphatase-like, core domain" CG3264 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" viable FBgn0261864 lzb lazybones http://flybase.net/reports/FBgn0261864.html gene 0035177=larval foraging behavior 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034173 CG9010 http://flybase.net/reports/FBgn0034173.html FBgn0044749 protein_coding_gene "0004365=glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, 0051287=NAD binding, 0050661=NADP binding" "0055114=oxidation-reduction process, 0006006=glucose metabolic process" anon-WO0140519.132 "IPR020828=Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR020831=Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR020829=Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR006424=Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020830=Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR016040=NAD(P)-binding domain" CG9010 16-Dec-15 2015_12 viable FBgn0266402 CR45042 http://flybase.net/reports/FBgn0266402.html non_protein_coding_gene CR45042 16-Dec-15 2015_12 FBgn0259647 B0091 http://flybase.net/reports/FBgn0259647.html gene 16-Dec-15 2015_12 visible wing FBgn0001029 Fs(3)Bak Female sterile (3) Baksa http://flybase.net/reports/FBgn0001029.html gene 0009792=embryo development ending in birth or egg hatching "Bak, Fs(3)Sz3, Fs(3)Baksa" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,dominant,maternal effect,some die during embryonic stage" FBgn0086215 jhu2388 http://flybase.net/reports/FBgn0086215.html gene 16-Dec-15 2015_12 "presumptive embryonic salivary gland,circular visceral muscle primordium" FBgn0050083 CG30083 http://flybase.net/reports/FBgn0050083.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG30083 16-Dec-15 2015_12 WBGene00006621(try-3) viable FBgn0026201 mog mogura http://flybase.net/reports/FBgn0026201.html gene mgr 16-Dec-15 2015_12 "radiation sensitive,visible" eye FBgn0030055 CG12772 http://flybase.net/reports/FBgn0030055.html protein_coding_gene 0005515=protein binding 0010507=negative regulation of autophagy 0005769=early endosome "FBgn 30055, Rubicon" IPR025258=Putative zinc-RING and/or ribbon CG12772 16-Dec-15 2015_12 ENSDARG00000030633(si:dkey-159b16.1) WBGene00013235(Y56A3A.16) ENSMUSG00000035629(1700021K19Rik) ENSG00000145016(KIAA0226) "viable,fertile" FBgn0264002 MsR2 Myosuppressin receptor 2 http://flybase.net/reports/FBgn0264002.html "FBgn0035330, FBgn0035329, FBgn0046578, FBgn0046579" protein_coding_gene "0004930=G-protein coupled receptor activity, 0035013=myosuppressin receptor activity, 0008188=neuropeptide receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0045932=negative regulation of muscle contraction, 0008344=adult locomotory behavior, 0002209=behavioral defense response, 0007193=adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway, 0008345=larval locomotory behavior" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "DmsR, anon-WO0170980.161, DMSR-2, CG13802, anon-WO0170980.160, CG43745, DmsR-2, CG13803, Dm CG13803, Dromyosuppressin receptor 2, DMS-R2, DMS-receptor2" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR019427=7TM GPCR, serpentine receptor class w (Srw), IPR000276=G protein-coupled receptor, rhodopsin-like" CG43745 16-Dec-15 2015_12 "ENSDARG00000063156,ENSDARG00000015601" "WBGene00010191(F57B7.1),WBGene00007951(C35A5.7)" "ENSMUSG00000066197(Gpr139),ENSMUSG00000034677(Gpr142)" "ENSG00000180269(GPR139),ENSG00000221981" DRSC22440 E 0.526483414 0.355720274 1.580070182 0.124020341 0.811318223 -0.171148876 FBgn0024620 meso3 meso3 http://flybase.net/reports/FBgn0024620.html FBgn0024480 gene Clone3 16-Dec-15 2015_12 FBgn0067673 ninja\pol pol http://flybase.net/reports/FBgn0067673.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0015074=DNA integration "IPR001878=Zinc finger, CCHC-type, IPR005312=Protein of unknown function DUF1759, IPR008042=Retrotransposon, Pao, IPR012337=Ribonuclease H-like domain, IPR001584=Integrase, catalytic core" 16-Dec-15 2015_12 FBgn0002481 l(3)SG38 lethal (3) SG38 http://flybase.net/reports/FBgn0002481.html gene l(3)m45 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0003927 snRNA:U3:82E small nuclear RNA U3 at 82E http://flybase.net/reports/FBgn0003927.html FBgn0003925 snRNA_gene "0000398=mRNA splicing, via spliceosome" "U3snRNA, snRNA[[2]], snRNA3, small nuclear RNA U3, snRNA2, U3snRNA82E, K7, snRNA:U3" 16-Dec-15 2015_12 FBgn0051008 CG31008 http://flybase.net/reports/FBgn0051008.html FBgn0045808 protein_coding_gene "BEST:GH26101, bs08f11.y1" IPR010625=CHCH CG31008 16-Dec-15 2015_12 YMR002W(MIC17) viable FBgn0260593 2L2653 http://flybase.net/reports/FBgn0260593.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0052285 tRNA:CR32285 transfer RNA:CR32285 http://flybase.net/reports/FBgn0052285.html "FBgn0011886, FBgn0011899, FBgn0060190" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K:CTT:AE002584-a, transfer RNA:lys2:63B, tRNA:K2:63B, tRNA:lys2:63B, AE002584.trna17-LysCTT, CR32285, chr3L.trna17-LysCTT, tRNA:K2, tRNA[Lys][[2]]" CR32285 16-Dec-15 2015_12 FBgn0260228 CG42502 http://flybase.net/reports/FBgn0260228.html protein_coding_gene Dromel_CG10570_FBtr0081122_uORF CG42502 16-Dec-15 2015_12 FBgn0263952 BG00907 http://flybase.net/reports/FBgn0263952.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0043872 nompE no mechanoreceptor potential E http://flybase.net/reports/FBgn0043872.html gene 0007605=sensory perception of sound 16-Dec-15 2015_12 "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0028404 Sema-3a Sema-3a http://flybase.net/reports/FBgn0028404.html gene 0007411=axon guidance 0005886=plasma membrane "semaphorin, semiphorin, Sema3A, Dsema3a" 16-Dec-15 2015_12 FBgn0042167 CG18847 http://flybase.net/reports/FBgn0042167.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038876 CG5919 http://flybase.net/reports/FBgn0038876.html protein_coding_gene "0004452=isopentenyl-diphosphate delta-isomerase activity, 0016787=hydrolase activity" 0008299=isoprenoid biosynthetic process 0005777=peroxisome IPPI "IPR015797=NUDIX hydrolase domain-like, IPR000086=NUDIX hydrolase domain, IPR011876=Isopentenyl-diphosphate delta-isomerase, type 1" CG5919 16-Dec-15 2015_12 ENSDARG00000019976(idi1) YPL117C(IDI1) WBGene00019460(idi-1) ENSXETG00000018088(idi1) "ENSMUSG00000058258(Idi1),ENSMUSG00000033520(Idi2),ENSMUSG00000021148(Gm9745)" "ENSG00000067064(IDI1),ENSG00000148377(IDI2)" "viable,visible" tormogen cell FBgn0026874 CG13358 http://flybase.net/reports/FBgn0026874.html protein_coding_gene EG:34F3.10 CG13358 16-Dec-15 2015_12 FBgn0052857 CG32857 http://flybase.net/reports/FBgn0052857.html protein_coding_gene "0008026=ATP-dependent helicase activity, 0005524=ATP binding, 0051536=iron-sulfur cluster binding, 0005506=iron ion binding, 0003676=nucleic acid binding" 0016226=iron-sulfur cluster assembly "IPR014824=Scaffold protein Nfu/NifU, N-terminal, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR017065=NFU1 iron-sulfur cluster scaffold homologue, IPR001075=NIF system FeS cluster assembly, NifU, C-terminal" CG32857 16-Dec-15 2015_12 ENSDARG00000068125(hirip5) YKL040C(NFU1) WBGene00003064(lpd-8) ENSXETG00000008202(NFU1) ENSMUSG00000029993(Nfu1) ENSG00000169599(NFU1) FBgn0085512 RYa RYamide http://flybase.net/reports/FBgn0085512.html FBan0040733 protein_coding_gene 0048018=receptor agonist activity "2000252=negative regulation of feeding behavior, 0007166=cell surface receptor signaling pathway" "0005615=extracellular space, 0005576=extracellular region" "CG40733, RYamide, dRYamide" CG40733 16-Dec-15 2015_12 FBgn0025824 HelIII HelIII http://flybase.net/reports/FBgn0025824.html gene 0004386=helicase activity DHEL III 16-Dec-15 2015_12 FBgn0000270 ccd central complex deranged http://flybase.net/reports/FBgn0000270.html gene 16-Dec-15 2015_12 "learning defective,recessive,memory defective,locomotor behavior defective" ellipsoid body FBgn0000939 fs(2)A9 female sterile (2) A9 http://flybase.net/reports/FBgn0000939.html gene 16-Dec-15 2015_12 "female sterile,recessive" "female reproductive system,egg,chorion,nucleus | pre-blastoderm stage" FBgn0005388 fs(1)A457 female sterile (1) A457 http://flybase.net/reports/FBgn0005388.html "FBgn0000757, FBgn0000772" gene "fs(1)M22, fs(1)457" 16-Dec-15 2015_12 "female sterile,recessive,lethal,non-rescuable maternal effect,maternal effect,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,rescuable maternal effect" "gastrula embryo,blastoderm embryo,rescuable maternal effect,egg,maternal effect" FBgn0039124 tbrd-1 testis-specifically expressed bromodomain containing protein-1 http://flybase.net/reports/FBgn0039124.html protein_coding_gene 0003682=chromatin binding "0000398=mRNA splicing, via spliceosome, 0007283=spermatogenesis, 0048515=spermatid differentiation" "0016604=nuclear body, 0005694=chromosome, 0005730=nucleolus, 0071011=precatalytic spliceosome" "tBRD-1, CG13597" "IPR018359=Bromodomain, conserved site, IPR001487=Bromodomain" CG13597 16-Dec-15 2015_12 "male sterile,male fertile,viable" "spermatid,Nebenkern,sperm individualization complex" FBgn0031664 CG8892 http://flybase.net/reports/FBgn0031664.html protein_coding_gene UBX domain 7 like "IPR009060=UBA-like, IPR001012=UBX domain, IPR012336=Thioredoxin-like fold, IPR029071=Ubiquitin-related domain, IPR017346=UBX domain-containing protein 2/7, IPR006577=UAS" CG8892 16-Dec-15 2015_12 ENSDARG00000009436(zgc:92437) ENSXETG00000003125(UBXN7) ENSMUSG00000053774(Ubxn7) ENSG00000163960(UBXN7) viable FBgn0034903 CG9850 http://flybase.net/reports/FBgn0034903.html "FBgn0034905, FBtr0072092, FBpp0072001, FBtr0072244, FBpp0072153" protein_coding_gene 0004222=metalloendopeptidase activity "0008283=cell proliferation, 0006508=proteolysis" "Dlg-interacting metalloprotease, CG11169, dimp, Dimp" "IPR024079=Metallopeptidase, catalytic domain, IPR001590=Peptidase M12B, ADAM/reprolysin" CG9850 16-Dec-15 2015_12 "viable,fertile" DRSC04089 E -0.253965377 0.560930084 1.780878089 0.499976519 -0.495817229 0.746732139 FBgn0050355 CG30355 http://flybase.net/reports/FBgn0050355.html "FBgn0046008, FBgn0046010, FBgn0046073, FBgn0046086, FBgn0046093, FBgn0047333" protein_coding_gene "NEST:bs23e07, NEST:bs06e10, BcDNA:AT24812, NEST:bs23a07, NEST:bs04f07, NEST:bs10b08" CG30355 16-Dec-15 2015_12 viable FBgn0021785 l(3)02670 lethal (3) 02670 http://flybase.net/reports/FBgn0021785.html gene l(2)02670 16-Dec-15 2015_12 lethal FBgn0263599 l(3)72Ab lethal (3) 72Ab http://flybase.net/reports/FBgn0263599.html "FBgn0004713, FBgn0036548, FBgn0026003" protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0003724=RNA helicase activity, 0003676=nucleic acid binding" "0007067=mitotic nuclear division, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0008380=RNA splicing, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005682=U5 snRNP, 0005681=spliceosomal complex, 0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome" "brr2, Brr2, CG5931, anon-EST:Liang-1.21, clone 1.21, cg5931, ASCC3L1" "IPR000008=C2 domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014756=Immunoglobulin E-set, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR004179=Sec63 domain" CG5931 16-Dec-15 2015_12 YER172C(BRR2) WBGene00012896(Y46G5A.4) ENSXETG00000001243(SNRNP200) ENSMUSG00000003660(Snrnp200) ENSG00000144028(SNRNP200) DRSC10559 IE -0.824683325 2.703476299 -2.048692294 -0.893859185 -1.160825837 -0.489464655 FBgn0034345 CG5174 http://flybase.net/reports/FBgn0034345.html "FBgn0064829, FBgn0064902" protein_coding_gene "BcDNA:RE18604, BcDNA:RH27395" IPR007327=Tumour protein D52 CG5174 16-Dec-15 2015_12 "ENSDARG00000013655(tpd52l2b),ENSDARG00000027154(tpd52l2a),ENSDARG00000061713(si:ch211-203l9.2),ENSDARG00000042548(zgc:110003)" "ENSXETG00000010413(TPD52),ENSXETG00000021842(TPD52L1)" "ENSMUSG00000027506(Tpd52),ENSMUSG00000000296(Tpd52l1),ENSMUSG00000000827(Tpd52l2),ENSMUSG00000024815(Trpd52l3)" "ENSG00000101150(TPD52L2),ENSG00000111907(TPD52L1),ENSG00000076554(TPD52),ENSG00000170777(TPD52L3)" "viable,fertile" FBgn0020819 l(3)98Dk lethal (3) 98Dk http://flybase.net/reports/FBgn0020819.html gene M31 16-Dec-15 2015_12 "lethal,recessive" FBgn0069408 JJF178 JJF178 http://flybase.net/reports/FBgn0069408.html gene 16-Dec-15 2015_12 stress response defective FBgn0060687 l(3)S074913 lethal (3) S074913 http://flybase.net/reports/FBgn0060687.html gene 0749/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0013610 l(3)E8-3-54 lethal (3) E8-3-54 http://flybase.net/reports/FBgn0013610.html gene 16-Dec-15 2015_12 lethal FBgn0264549 CR43928 http://flybase.net/reports/FBgn0264549.html non_protein_coding_gene CR43928 16-Dec-15 2015_12 FBgn0060751 l(3)S064912 lethal (3) S064912 http://flybase.net/reports/FBgn0060751.html gene 0649/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0036279 Ncc69 sodium chloride cotransporter 69 http://flybase.net/reports/FBgn0036279.html FBgn0025706 protein_coding_gene "0015378=sodium:chloride symporter activity, 0015171=amino acid transmembrane transporter activity, 0008511=sodium:potassium:chloride symporter activity" "0006821=chloride transport, 0003333=amino acid transmembrane transport, 0006813=potassium ion transport, 0035826=rubidium ion transport" "0016021=integral component of membrane, 0005886=plasma membrane" "CG43567, NKCC, NCC69, CK01027, mdcds_25302, CG4357, BEST:CK01027" "IPR004842=SLC12A transporter family, IPR004841=Amino acid permease/ SLC12A domain, IPR018491=SLC12A transporter, C-terminal, IPR002443=Na/K/Cl co-transporter" CG4357 16-Dec-15 2015_12 "ENSDARG00000013855(slc12a3),ENSDARG00000013743(LOC100003286),ENSDARG00000055313(slc12a10.1),ENSDARG00000055253(slc12a10.3),ENSDARG00000071173(slc12a10.2)" WBGene00012543(nkcc-1) "ENSXETG00000008777(SLC12A1),ENSXETG00000019997(SLC12A3)" "ENSMUSG00000024597(Slc12a2),ENSMUSG00000027202(Slc12a1),ENSMUSG00000031766(Slc12a3)" "ENSG00000064651(SLC12A2),ENSG00000074803(SLC12A1),ENSG00000070915(SLC12A3)" "viable,neuroanatomy defective,fertile,bang sensitive,paralytic" "abdominal nerve,abdominal nerve | third instar larval stage" DRSC10413 I 1.940446653 1.702325733 0.728097408 1.081331537 -0.191863888 -0.223638111 FBgn0051053 CG31053 http://flybase.net/reports/FBgn0051053.html protein_coding_gene 0008270=zinc ion binding "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG31053 16-Dec-15 2015_12 "WBGene00008387(D1081.9),WBGene00018867(F55A12.10)" ENSMUSG00000071425(Gm10332) ENSG00000215277(LOC100507650) viable FBgn0069942 CG41101 http://flybase.net/reports/FBgn0069942.html protein_coding_gene 16-Dec-15 2015_12 FBgn0015782 Pa Puffrmel http://flybase.net/reports/FBgn0015782.html gene 16-Dec-15 2015_12 "visible,dominant" wing FBgn0017444 anon-15Dc anon-15Dc http://flybase.net/reports/FBgn0017444.html gene transcript d 16-Dec-15 2015_12 FBgn0004035 yea1 yeast 1 http://flybase.net/reports/FBgn0004035.html gene 16-Dec-15 2015_12 FBgn0002142 l(2)K327 lethal (2) K327 http://flybase.net/reports/FBgn0002142.html gene 16-Dec-15 2015_12 lethal FBgn0002769 mit(1)21 mitotic 21 http://flybase.net/reports/FBgn0002769.html gene 16-Dec-15 2015_12 FBgn0267322 CR45758 http://flybase.net/reports/FBgn0267322.html non_protein_coding_gene CR45758 16-Dec-15 2015_12 FBgn0265853 CR44642 http://flybase.net/reports/FBgn0265853.html non_protein_coding_gene CR44642 16-Dec-15 2015_12 FBgn0022153 l(2)k05819 lethal (2) k05819 http://flybase.net/reports/FBgn0022153.html FBgn0044723 protein_coding_gene "anon-WO0140519.156, CG3054" "IPR023298=P-type ATPase, transmembrane domain" CG3054 16-Dec-15 2015_12 WBGene00017010(D1007.15) ENSXETG00000012524(KIAA0195) ENSMUSG00000020747(2310067B10Rik) ENSG00000177728(KIAA0195) "lethal,recessive,viable,fertile" FBgn0032373 Vha100-5 Vacuolar H+ ATPase 100kD subunit 5 http://flybase.net/reports/FBgn0032373.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "vha100-5, Vacuolar H[+] ATPase subunit 100-5, CG12602" "IPR026028=ATPase, V0 complex, subunit 116kDa, eukaryotic, IPR002490=V-type ATPase, V0 complex, 116kDa subunit family" CG12602 16-Dec-15 2015_12 "YOR270C(VPH1),YMR054W(STV1)" "visible,viable" wing DRSC02175 IEK 1.635735752 -1.118750573 -1.286887755 -2.065949073 1.529998519 0.080140718 FBgn0082939 snoRNA:Me28S-C3227b snoRNA:Me28S-C3227b http://flybase.net/reports/FBgn0082939.html snoRNA_gene "CR34534, Me28S-Cm3227b" CR34534 16-Dec-15 2015_12 FBgn0010470 Fkbp14 FK506-binding protein 14 ortholog http://flybase.net/reports/FBgn0010470.html "FBgn0027068, FBgn0064945" protein_coding_gene "0005509=calcium ion binding, 0005528=FK506 binding, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0008587=imaginal disc-derived wing margin morphogenesis, 0002121=inter-male aggressive behavior, 0008593=regulation of Notch signaling pathway, 0006457=protein folding, 0007444=imaginal disc development, 0022416=chaeta development, 0046716=muscle cell cellular homeostasis, 0018208=peptidyl-proline modification" "0012505=endomembrane system, 0016020=membrane, 0005783=endoplasmic reticulum, 0005615=extracellular space" "FKBP14, Fkbp13, GM07659, l(2)00734, FKBP13, fkbp13, BcDNA:GM07659, BcDNA.GM07659, CG9847, BcDNA:GH08925, FKB13" "IPR002048=EF-hand domain, IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG9847 16-Dec-15 2015_12 "ENSDARG00000040695(fkbp14),ENSDARG00000010962(fkbp7)" "ENSXETG00000008998(fkbp14),ENSXETG00000015018(fkbp7)" "ENSMUSG00000038074(Fkbp14),ENSMUSG00000002732(Fkbp7)" ENSG00000106080(FKBP14) "lethal - all die before end of P-stage,lethal,female sterile,germline clone,cell lethal,somatic clone,viable,behavior defective,recessive,long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective,fertile,neuroanatomy defective" "mesothoracic bristle,notal microchaeta,wing margin,wing margin bristle,sensory mother cell,wing disc,imaginal disc,synapse" FBgn0263769 CR43686 http://flybase.net/reports/FBgn0263769.html non_protein_coding_gene CR43686 16-Dec-15 2015_12 FBgn0021985 l(2)k09837 lethal (2) k09837 http://flybase.net/reports/FBgn0021985.html gene 16-Dec-15 2015_12 FBgn0025797 Su(var)401 Suppressor of variegation 401 http://flybase.net/reports/FBgn0025797.html gene Su-var(2)401 16-Dec-15 2015_12 FBgn0082945 snoRNA:Me28S-A2634b snoRNA:Me28S-A2634b http://flybase.net/reports/FBgn0082945.html snoRNA_gene "Me28S-A2634b, Me28S-Am2634b, CR34635" CR34635 16-Dec-15 2015_12 FBgn0266114 CR44840 http://flybase.net/reports/FBgn0266114.html non_protein_coding_gene CR44840 16-Dec-15 2015_12 FBgn0033294 Mal-A4 Maltase A4 http://flybase.net/reports/FBgn0033294.html protein_coding_gene "0043169=cation binding, 0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process "Drome_A4, CG8693, mal_A4" "IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR015902=Glycoside hydrolase, family 13, IPR013781=Glycoside hydrolase, catalytic domain" CG8693 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable DRSC07236 K -0.625453206 -0.343737192 0.532224439 -0.705245538 -0.502000565 1.876948051 FBgn0045840 ëÈDsubFC4 ëÈDsubFC4 http://flybase.net/reports/FBgn0045840.html gene 16-Dec-15 2015_12 FBgn0040987 CG15139 http://flybase.net/reports/FBgn0040987.html protein_coding_gene 16-Dec-15 2015_12 FBgn0045465 HP1c::Su(var)205 HP1c::Su(var)205 http://flybase.net/reports/FBgn0045465.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0086077 snoRNA:Me18S-G962 http://flybase.net/reports/FBgn0086077.html snoRNA_gene "CR34706, Me18S-Gm962" CR34706 16-Dec-15 2015_12 FBgn0033402 Myd88 Myd88 http://flybase.net/reports/FBgn0033402.html protein_coding_gene "0005546=phosphatidylinositol-4,5-bisphosphate binding, 0005121=Toll binding, 0005515=protein binding" "0019732=antifungal humoral response, 0009953=dorsal/ventral pattern formation, 0006952=defense response, 0050830=defense response to Gram-positive bacterium, 0002804=positive regulation of antifungal peptide production, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0002781=antifungal peptide production, 0045087=innate immune response, 0006955=immune response, 0009620=response to fungus, 0006965=positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria, 0008063=Toll signaling pathway, 0007165=signal transduction, 0050832=defense response to fungus" 0005886=plasma membrane "dMyD88, krapfen, myd88, dMYd88, EP(2)2535, DmMyd88, DmMyD88, Myd88F, dMyd88, LD20892, Kra, MyD88, CG2078, DMMYD88, MYD88, kra" "IPR011029=Death-like domain, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain" CG2078 16-Dec-15 2015_12 ENSDARG00000010169(myd88) ENSXETG00000018434(myd88) ENSMUSG00000032508(Myd88) ENSG00000172936(MYD88) "immune response defective,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female fertile,viable,lethal,dorsal/ventral axis specification defective,germline clone,non-rescuable maternal effect" "filzkorper,denticle belt,embryonic epidermis,ventral" FBgn0024993 CG2662 http://flybase.net/reports/FBgn0024993.html protein_coding_gene 0008270=zinc ion binding "EG:100G10.6, shrunken nuts, MAD, snuts" "IPR019787=Zinc finger, PHD-finger, IPR013761=Sterile alpha motif/pointed domain, IPR001965=Zinc finger, PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR001660=Sterile alpha motif domain" CG2662 16-Dec-15 2015_12 viable DRSC18468 IK 2.18349238 1.75573769 1.082161342 0.172355973 1.689209517 0.294458768 FBgn0267154 CR45594 http://flybase.net/reports/FBgn0267154.html non_protein_coding_gene CR45594 16-Dec-15 2015_12 FBgn0037429 Osi19 Osiris 19 http://flybase.net/reports/FBgn0037429.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG15189" IPR012464=Protein of unknown function DUF1676 CG15189 16-Dec-15 2015_12 FBgn0029161 slmo slowmo http://flybase.net/reports/FBgn0029161.html FBgn0031767 protein_coding_gene "0007283=spermatogenesis, 0008345=larval locomotory behavior, 0030537=larval behavior, 0030432=peristalsis, 0030706=germarium-derived oocyte differentiation" 0005739=mitochondrion "kisir, Kisir, CT26166, CG9131, slmo" IPR006797=PRELI/MSF1 domain CG9131 16-Dec-15 2015_12 "ENSDARG00000009505(slmo2),ENSDARG00000055288(LOC563270)" "YLR168C(UPS2),YDR185C(UPS3)" WBGene00008856(F15D3.6) ENSXETG00000027289(SLMO1) "ENSMUSG00000016257(Slmo2),ENSMUSG00000024530(Slmo1)" "ENSG00000101166(SLMO2),ENSG00000141391(SLMO1)" "viable,male sterile,recessive,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,lethal,flight defective,visible" "wing,trichogen cell,mesothoracic tergum" DRSC03143 IEK -1.518622585 -1.072497697 -0.957496416 -2.747169355 1.595478521 0.490373303 FBgn0033154 CG1850 http://flybase.net/reports/FBgn0033154.html protein_coding_gene CG1850 16-Dec-15 2015_12 viable FBgn0010062 M(2)34d M(2)34d http://flybase.net/reports/FBgn0010062.html gene 16-Dec-15 2015_12 visible eye FBgn0065512 l(2)SH1166 lethal (2) SH1166 http://flybase.net/reports/FBgn0065512.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005038 Est-A Esterase A http://flybase.net/reports/FBgn0005038.html gene 0052689=carboxylic ester hydrolase activity Est18 16-Dec-15 2015_12 electrophoretic variant FBgn0085762 CG40648 http://flybase.net/reports/FBgn0085762.html FBan0040648 protein_coding_gene CR40648 16-Dec-15 2015_12 FBgn0267875 CR46163 http://flybase.net/reports/FBgn0267875.html pseudogene_attribute ade5-related CR46163 16-Dec-15 2015_12 FBgn0031947 CG7154 http://flybase.net/reports/FBgn0031947.html protein_coding_gene 0003677=DNA binding 0048812=neuron projection morphogenesis 0005634=nucleus "IPR001487=Bromodomain, IPR021900=Protein of unknown function DUF3512" CG7154 16-Dec-15 2015_12 ENSDARG00000008380(brd7) WBGene00007256(tag-298) ENSXETG00000018460(brd7) ENSMUSG00000031660(Brd7) ENSG00000166164(BRD7) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC03017 E -0.697418664 0.719613499 0.226420442 -1.509175214 -0.521056247 1.062154707 FBgn0030718 ND-20 NADH dehydrogenase (ubiquinone) 20 kDa subunit http://flybase.net/reports/FBgn0030718.html protein_coding_gene "0051539=4 iron, 4 sulfur cluster binding, 0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity, 0048038=quinone binding" "0000302=response to reactive oxygen species, 2000331=regulation of terminal button organization, 0008340=determination of adult lifespan, 0032981=mitochondrial respiratory chain complex I assembly, 0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH-UBIQUINONE OXIDOREDUCTASE 20 KDA SUBUNIT, NUKM, FBpp0073949, NADH ubiquinone oxidoreductase 20 kDa, NADH:ubiquinone oxidoreductase 20 kDa subunit, CG9172, 20 kDa" "IPR006137=NADH:ubiquinone oxidoreductase-like, 20kDa subunit, IPR006138=NADH-ubiquinone oxidoreductase, 20 Kd subunit" CG9172 16-Dec-15 2015_12 WBGene00012376(nduf-7) ENSXETG00000003702() ENSMUSG00000020153(Ndufs7) "lethal - all die before end of larval stage,some die during larval stage,long lived,female,RU486 conditional,female semi-fertile,stress response defective,viable,visible" "trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0020280 laf labial associated factor http://flybase.net/reports/FBgn0020280.html "FBgn0015605, FBgn0037285" protein_coding_gene 0001700=embryonic development via the syncytial blastoderm 0005634=nucleus "C6, CG14660, clone C6" CG14660 16-Dec-15 2015_12 viable FBgn0001847 l(1)ts3803 lethal (1) ts3803 http://flybase.net/reports/FBgn0001847.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0045053 fs(1)221a female sterile (1) 221a http://flybase.net/reports/FBgn0045053.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "nurse cell & nucleus,nurse cell,follicle cell,border follicle cell" FBgn0260756 CG42554 http://flybase.net/reports/FBgn0260756.html "FBgn0035163, FBan0013886" protein_coding_gene 0022008=neurogenesis "CG13886, CT33419" CG42554 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,mesothoracic tergum" FBgn0004991 chy chunky http://flybase.net/reports/FBgn0004991.html gene 16-Dec-15 2015_12 "wing,adult abdomen" FBgn0010930 l(3)08724 lethal (3) 08724 http://flybase.net/reports/FBgn0010930.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083080 luke lucky luke http://flybase.net/reports/FBgn0083080.html gene 16-Dec-15 2015_12 FBgn0069958 CG41059 http://flybase.net/reports/FBgn0069958.html FBan0041059 protein_coding_gene 16-Dec-15 2015_12 FBgn0051820 CG31820 http://flybase.net/reports/FBgn0051820.html "FBgn0045078, FBgn0045344" protein_coding_gene "NEST:bs10d03, NEST:bs36g10" CG31820 16-Dec-15 2015_12 viable FBgn0004032 wz wizened http://flybase.net/reports/FBgn0004032.html gene shrunken-3 16-Dec-15 2015_12 "sterile,recessive,visible,body color defective" macrochaeta FBgn0044040 Masc29a Masc29a http://flybase.net/reports/FBgn0044040.html gene 16-Dec-15 2015_12 FBgn0051862 CG31862 http://flybase.net/reports/FBgn0051862.html protein_coding_gene CG31862 16-Dec-15 2015_12 viable FBgn0053648 CG33648 http://flybase.net/reports/FBgn0053648.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33648 16-Dec-15 2015_12 FBgn0263331 CR43412 http://flybase.net/reports/FBgn0263331.html non_protein_coding_gene CR43412 16-Dec-15 2015_12 FBgn0086611 Lcp65Ag3 Larval cuticle protein http://flybase.net/reports/FBgn0086611.html "FBgn0023195, FBgn0042120" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Larval cuticle protein, Lcp-g3, CG18779, g3, DmelLcp65Ag3" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG18779 16-Dec-15 2015_12 " larval stage , embryonic stage , pupal stage | 7-13 hr " FBgn0030815 CG8945 http://flybase.net/reports/FBgn0030815.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis Cg8945 "IPR009020=Proteinase inhibitor, propeptide, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG8945 16-Dec-15 2015_12 "viable,fertile" FBgn0038046 CG5641 http://flybase.net/reports/FBgn0038046.html protein_coding_gene "0005524=ATP binding, 0003725=double-stranded RNA binding, 0003677=DNA binding, 0016740=transferase activity" "0006955=immune response, 0045893=positive regulation of transcription, DNA-templated, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005730=nucleolus, 0005634=nucleus, 0071011=precatalytic spliceosome" Interleukin enhancer binding factor "IPR006116=2-5-oligoadenylate synthetase, N-terminal, IPR006561=DZF domain" CG5641 16-Dec-15 2015_12 ENSDARG00000014591(ilf2) WBGene00011253(R11H6.5) ENSXETG00000014290(ilf2) ENSMUSG00000001016(Ilf2) ENSG00000143621(ILF2) viable DRSC15852 E 0.126167555 -0.339090084 -1.603873037 0.347652821 -0.241072059 -0.20936792 FBgn0032421 crok crooked http://flybase.net/reports/FBgn0032421.html FBgn0047066 protein_coding_gene "0035151=regulation of tube size, open tracheal system, 0019991=septate junction assembly" 0005737=cytoplasm "crok, crooked, BcDNA:RE65321, CG17218" CG17218 16-Dec-15 2015_12 WBGene00015803(C15H9.9) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,presumptive embryonic salivary gland,embryonic/larval tracheal system,septate junction" FBgn0002821 ms(2)11R male sterile (2) 11R http://flybase.net/reports/FBgn0002821.html gene 16-Dec-15 2015_12 male sterile FBgn0034217 Lhr Lethal hybrid rescue http://flybase.net/reports/FBgn0034217.html protein_coding_gene "0005515=protein binding, 0003677=DNA binding" "0000070=mitotic sister chromatid segregation, 0000723=telomere maintenance, 0010528=regulation of transposition, 0010529=negative regulation of transposition" "0035012=polytene chromosome, telomeric region, 0010369=chromocenter, 0000775=chromosome, centromeric region, 0000792=heterochromatin" "LHR[[mel]], mel-Lhr, CG18468, HP3, LHR, lethal hybrid rescue" IPR004210=BESS motif CG18468 16-Dec-15 2015_12 "female semi-sterile,recessive,progressive,viable" FBgn0001784 l(1)M82 lethal (1) M82 http://flybase.net/reports/FBgn0001784.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" macrochaeta FBgn0263869 CR43716 http://flybase.net/reports/FBgn0263869.html non_protein_coding_gene CR43716 16-Dec-15 2015_12 FBgn0030317 CG1561 http://flybase.net/reports/FBgn0030317.html protein_coding_gene e "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG1561 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" partially lethal - majority die FBgn0065373 l(2)SH1692 lethal (2) SH1692 http://flybase.net/reports/FBgn0065373.html gene l(2)SH2 1692 16-Dec-15 2015_12 "lethal,recessive" FBgn0001341 l(1)1Bi lethal (1) 1Bi http://flybase.net/reports/FBgn0001341.html protein_coding_gene "0003677=DNA binding, 0003887=DNA-directed DNA polymerase activity" "0006351=transcription, DNA-templated" 0005730=nucleolus "Lethal (1) 1Bi, l(1)lBi, l(1)Bi, HM-52, HM-419, CG6189, EG:115C2.2" "IPR016024=Armadillo-type fold, IPR007015=DNA polymerase V" CG6189 16-Dec-15 2015_12 ENSDARG00000028323(LOC100329401) ENSMUSG00000040463(Mybbp1a) ENSG00000132382(MYBBP1A) " adult stage , embryonic stage " "wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" macrochaeta FBgn0261679 CG42726 http://flybase.net/reports/FBgn0261679.html "FBgn0051392, FBan0031392, FBgn0038322" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "CG12258, CG31392" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG42726 16-Dec-15 2015_12 viable FBgn0000761 fs(1)A476 female sterile (1) A476 http://flybase.net/reports/FBgn0000761.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0262544 CG43098 http://flybase.net/reports/FBgn0262544.html protein_coding_gene chr3L_3658997_3659727.0 CG43098 16-Dec-15 2015_12 FBgn0014077 anon-10Ba anon-10Ba http://flybase.net/reports/FBgn0014077.html gene anon-10B 16-Dec-15 2015_12 FBgn0060759 l(3)S063602 lethal (3) S063602 http://flybase.net/reports/FBgn0060759.html gene 0636/02 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0260817 gkt glaikit http://flybase.net/reports/FBgn0260817.html "FBgn0031506, FBgn0031507, FBgn0017439" protein_coding_gene 0017005=3'-tyrosyl-DNA phosphodiesterase activity "0007417=central nervous system development, 0006281=DNA repair, 0045197=establishment or maintenance of epithelial cell apical/basal polarity" 0005634=nucleus "CG8825, anon-23Db, Tdp1, Tyrosyl-DNA phosophodiesterase 1, CG8826, Glaikit, c22, Gkt, TDP1" "IPR027415=Tyrosyl-DNA phosphodiesterase C-terminal domain, IPR010347=Tyrosyl-DNA phosphodiesterase I, IPR019406=Zinc finger, C2H2, APLF-like" CG8825 16-Dec-15 2015_12 YBR223C(TDP1) WBGene00018678(F52C12.1) ENSXETG00000015693(tdp1) ENSMUSG00000021177(Tdp1) ENSG00000042088(TDP1) FBgn0017602 Hrb3 Hrb3 http://flybase.net/reports/FBgn0017602.html gene 16-Dec-15 2015_12 FBgn0265678 CR44485 http://flybase.net/reports/FBgn0265678.html non_protein_coding_gene CR44485 16-Dec-15 2015_12 FBgn0051939 tRNA:CR31939 transfer RNA:CR31939 http://flybase.net/reports/FBgn0051939.html FBgn0060106 tRNA_gene "0033428=CAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR31939, AE002638.trna6-GlnCTG, chr2L.trna39-GlnCTG, tRNA:Q:CTG:AE002638-c" CR31939 16-Dec-15 2015_12 FBgn0261877 Z2-2626 http://flybase.net/reports/FBgn0261877.html gene 0030431=sleep 16-Dec-15 2015_12 behavior defective FBgn0021792 l(2)k17031 lethal (2) k17031 http://flybase.net/reports/FBgn0021792.html gene l(2)k17035 16-Dec-15 2015_12 "lethal,recessive" FBgn0014453 17.6\pol 17.6 element transposase http://flybase.net/reports/FBgn0014453.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "pol, 17.6\T" "IPR021109=Aspartic peptidase domain, IPR012337=Ribonuclease H-like domain, IPR001584=Integrase, catalytic core, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0261708 CR42745 http://flybase.net/reports/FBgn0261708.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0037360 CG2182 http://flybase.net/reports/FBgn0037360.html protein_coding_gene IPR026073=Gametogenetin-binding protein 2 CG2182 16-Dec-15 2015_12 ENSDARG00000055086(ggnbp2) ENSXETG00000002038(znf403) ENSMUSG00000020530(Ggnbp2) ENSG00000005955(GGNBP2) viable FBgn0020828 l(2)SA104 lethal (2) SA104 http://flybase.net/reports/FBgn0020828.html gene l(2)SA#104 16-Dec-15 2015_12 FBgn0026227 l(1)16Fn lethal (1) 16Fn http://flybase.net/reports/FBgn0026227.html gene HL-IX 16-Dec-15 2015_12 FBgn0263611 CR43620 http://flybase.net/reports/FBgn0263611.html non_protein_coding_gene CR43620 16-Dec-15 2015_12 FBgn0032981 CG3635 http://flybase.net/reports/FBgn0032981.html FBan0003635 protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process "IPR006693=Partial AB-hydrolase lipase domain, IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold" CG3635 16-Dec-15 2015_12 YKL140W(TGL1) "WBGene00021963(Y57E12B.3),WBGene00010062(F54F3.3),WBGene00020016(R11G11.14),WBGene00022642(ZK6.7),WBGene00009773(F46B6.8)" ENSXETG00000009273(lipA) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0013799 Deaf1 Deformed epidermal autoregulatory factor-1 http://flybase.net/reports/FBgn0013799.html "FBtr0074882, FBpp0074651" protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0009792=embryo development ending in birth or egg hatching, 0045893=positive regulation of transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter, 0050776=regulation of immune response" "0005634=nucleus, 0005700=polytene chromosome" "deformed epidermal autoregulatory factor-1, Deaf-1, DEAF1, l(3)76BDv, CG8567, DEAF-1, deaf-1, deaf1" "IPR002893=Zinc finger, MYND-type, IPR010919=SAND domain-like, IPR024119=Transcription factor DEAF-1, IPR000770=SAND domain" CG8567 16-Dec-15 2015_12 ENSDARG00000063662 ENSMUSG00000058886(Deaf1) ENSG00000177030(DEAF1) embryonic stage | early

ubiquitous " embryonic stage , embryonic stage | stage >15 " "

ubiquitous , embryonic nervous system

" "lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,partially,visible,eye color defective,viable" "embryonic segment,non-rescuable maternal effect,dorsal closure embryo,heat sensitive,extended germ band embryo,wing,wing vein L3,mesothoracic bristle,scutellar bristle,eye,ommatidium,macrochaeta" DRSC22786 E -0.997237593 -0.579331667 -3.031508297 -0.737916073 -0.49978891 0.005221521 FBgn0031266 CG2807 http://flybase.net/reports/FBgn0031266.html FBgn0025944 protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005686=U2 snRNP, 0005681=spliceosomal complex" "SF3B, anon-21Cd, unnamed" "IPR015016=Splicing factor 3B subunit 1, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG2807 16-Dec-15 2015_12 ENSDARG00000056138(sf3b1) YMR288W(HSH155) WBGene00011605(T08A11.2) ENSXETG00000013339(SF3B1) ENSMUSG00000025982(Sf3b1) ENSG00000115524(SF3B1) lethal DRSC00535 IEK -1.485029124 2.2305001 -1.800193323 -4.542704503 -5.848987187 -4.354462971 FBgn0263545 mir-4963 mir-4963 stem loop http://flybase.net/reports/FBgn0263545.html miRNA_gene "dme-mir-4963, CR43530" CR43530 16-Dec-15 2015_12 FBgn0262020 CG42831 http://flybase.net/reports/FBgn0262020.html protein_coding_gene CG42831 16-Dec-15 2015_12 FBgn0262952 mt:ND4 mitochondrial NADH-ubiquinone oxidoreductase chain 4 http://flybase.net/reports/FBgn0262952.html "FBgn0013682, FBgn0002867, FBgn0083932" protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity "0006120=mitochondrial electron transport, NADH to ubiquinone" "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "CG34085, nad4, CK00534, BEST:CK00534, ND4, URF4, nd4" "IPR001750=NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, IPR000260=NADH:ubiquinone oxidoreductase chain 4, N-terminal, IPR003918=NADH:ubiquinone oxidoreductase" CG34085 16-Dec-15 2015_12 ENSDARG00000063917 WBGene00010963(MTCE.25) "ENSMUSG00000065947,ENSMUSG00000064363" "ENSG00000198886,ENSG00000198868" FBgn0016754 sba six-banded http://flybase.net/reports/FBgn0016754.html protein_coding_gene 0003677=DNA binding 0005634=nucleus "TF125 type II, DMTF125, F125, CG13598, TF125, Dm Sba, Tf125, AAF56201" "IPR016177=DNA-binding domain, IPR001739=Methyl-CpG DNA binding, IPR000313=PWWP domain" CG13598 16-Dec-15 2015_12 ENSXETG00000006239(MBD6) ENSMUSG00000036792(Mbd5) "ENSG00000166987(MBD6),ENSG00000204406(MBD5)" viable wing vein DRSC13643 IK -2.070235085 -1.41869342 -1.231892304 -1.499617228 -1.699100309 0.903474607 FBgn0035522 CG1273 http://flybase.net/reports/FBgn0035522.html protein_coding_gene 1273 CG1273 16-Dec-15 2015_12 "viable,fertile" FBgn0263441 CR43464 http://flybase.net/reports/FBgn0263441.html non_protein_coding_gene CR43464 16-Dec-15 2015_12 FBgn0084776 W220 W220 http://flybase.net/reports/FBgn0084776.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0045500 Gr22b Gustatory receptor 22b http://flybase.net/reports/FBgn0045500.html "FBgn0045491, FBgn0051931" protein_coding_gene 0008527=taste receptor activity 0050912=detection of chemical stimulus involved in sensory perception of taste 0016021=integral component of membrane "Gr22bP, CG31931, GR22b, Gustatory receptor 2940.4, CR31931, Gr2940.4" IPR013604=7TM chemoreceptor CG31931 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0267568 CR45908 http://flybase.net/reports/FBgn0267568.html non_protein_coding_gene CR45908 16-Dec-15 2015_12 FBgn0001719 l(1)ESHS40 lethal (1) ESHS40 http://flybase.net/reports/FBgn0001719.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031422 CG9870 http://flybase.net/reports/FBgn0031422.html protein_coding_gene "0016746=transferase activity, transferring acyl groups" 0006506=GPI anchor biosynthetic process "0016021=integral component of membrane, 0005789=endoplasmic reticulum membrane" IPR009447=GWT1 CG9870 16-Dec-15 2015_12 YJL091C(GWT1) WBGene00022447(Y110A2AL.12) ENSXETG00000002039(PIGW) ENSMUSG00000045140(Pigw) ENSG00000184886(PIGW) viable FBgn0264995 CR44146 http://flybase.net/reports/FBgn0264995.html non_protein_coding_gene CR44146 16-Dec-15 2015_12 FBgn0038114 CG11670 http://flybase.net/reports/FBgn0038114.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP27 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG11670 16-Dec-15 2015_12 "viable,fertile" FBgn0261991 CG42809 http://flybase.net/reports/FBgn0261991.html "FBgn0032526, FBan0016849" protein_coding_gene CG16849 CG42809 16-Dec-15 2015_12 FBgn0038251 Hexim HEXIM ortholog http://flybase.net/reports/FBgn0038251.html protein_coding_gene "0004861=cyclin-dependent protein serine/threonine kinase inhibitor activity, 0097322=7SK snRNA binding" 0000122=negative regulation of transcription from RNA polymerase II promoter "0005634=nucleus, 0005737=cytoplasm" "CG3508, dHEXIM" IPR024872=HEXIM CG3508 16-Dec-15 2015_12 "ENSMUSG00000043372(Hexim2),ENSMUSG00000048878(Hexim1)" "ENSG00000168517(HEXIM2),ENSG00000186834(HEXIM1)" "lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile" "leg,wing,eye" FBgn0028870 CG4691 http://flybase.net/reports/FBgn0028870.html FBgn0044583 protein_coding_gene "BG:DS06874.1, anon-WO0140519.47" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG4691 16-Dec-15 2015_12 viable FBgn0266283 ddt double double trouble http://flybase.net/reports/FBgn0266283.html gene 16-Dec-15 2015_12 "chemical sensitive,somatic clone,lethal,conditional" "eye,somatic clone,conditional" FBgn0052010 CR32010 http://flybase.net/reports/FBgn0052010.html pseudogene_attribute CG32010 CR32010 16-Dec-15 2015_12 FBgn0016779 anon-77Bc anon-77Bc http://flybase.net/reports/FBgn0016779.html gene "D, transcript D" 16-Dec-15 2015_12 FBgn0004123 l(2)43Bb lethal (2) 43Bb http://flybase.net/reports/FBgn0004123.html gene "l(2)04614, 43Bb" 16-Dec-15 2015_12 "lethal,recessive" FBgn0020269 mspo M-spondin http://flybase.net/reports/FBgn0020269.html protein_coding_gene 1901739=regulation of myoblast fusion 0005578=proteinaceous extracellular matrix "m-spo, Mspo, m-spondin, CT28539, CG10145" "IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR009465=Spondin, N-terminal" CG10145 16-Dec-15 2015_12 "ENSDARG00000025465(spon2a),ENSDARG00000002732(spon2b)" ENSMUSG00000037379(Spon2) ENSG00000159674(SPON2) "viable,fertile" "dorsal acute muscle 1,nucleus | supernumerary,nucleuseve.eme" FBgn0036827 CG6843 http://flybase.net/reports/FBgn0036827.html protein_coding_gene "IPR019339=CBF1-interacting co-repressor CIR, N-terminal domain" CG6843 16-Dec-15 2015_12 WBGene00018892(cir-1) ENSXETG00000008492(CIR1) ENSMUSG00000041777(Cir1) ENSG00000138433(CIR1) FBgn0264510 CR43909 http://flybase.net/reports/FBgn0264510.html non_protein_coding_gene CR43909 16-Dec-15 2015_12 FBgn0045859 csn casanova http://flybase.net/reports/FBgn0045859.html FBgn0046324 gene 0016231=beta-N-acetylglucosaminidase activity ms(3)HB156 16-Dec-15 2015_12 "male sterile,female fertile,viable,recessive" FBgn0060856 l(3)S048015a lethal (3) S048015a http://flybase.net/reports/FBgn0060856.html gene 0480/15 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259186 Ir60c Ionotropic receptor 60c http://flybase.net/reports/FBgn0259186.html "FBan0013582, FBgn0035015" pseudogene_attribute "DmelIR60c, CG42290, CG13582, ionotropic receptor 60c, IR60c, CR42290" CR42290 16-Dec-15 2015_12 FBgn0015001 ë_Try ë_Trypsin http://flybase.net/reports/FBgn0015001.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "SP129, iotaTry, trypsin iota, 143775_at, CG7754" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG7754 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" viable FBgn0085334 CG34305 http://flybase.net/reports/FBgn0085334.html protein_coding_gene CG34305 16-Dec-15 2015_12 FBgn0261639 CR42722 http://flybase.net/reports/FBgn0261639.html pseudogene_attribute CR42722 16-Dec-15 2015_12 FBgn0051390 MED7 Mediator complex subunit 7 http://flybase.net/reports/FBgn0051390.html FBgn0037830 protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0005515=protein binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex" "dTRAP34, Mediator, Med7, CG31390, CG6529, dMED7" "IPR009244=Mediator complex, subunit Med7" CG31390 16-Dec-15 2015_12 ENSDARG00000016318(med7) YOL135C(MED7) WBGene00002324(let-49) ENSXETG00000001505(crsp1) ENSMUSG00000020397(Med7) ENSG00000155868(MED7) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16059 IEK -2.266768988 1.656760997 -2.911276715 0.498031782 2.355447936 3.348135134 FBgn0037764 CG9459 http://flybase.net/reports/FBgn0037764.html "FBtr0082153, FBpp0081631" protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane CT26804 IPR002076=ELO family CG9459 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0085569 CG41242 http://flybase.net/reports/FBgn0085569.html FBan0041242 protein_coding_gene CG41242 16-Dec-15 2015_12 FBgn0052424 CG32424 http://flybase.net/reports/FBgn0052424.html protein_coding_gene 16-Dec-15 2015_12 FBgn0037313 CG1161 http://flybase.net/reports/FBgn0037313.html protein_coding_gene "0016021=integral component of membrane, 0016020=membrane" IPR008853=TMEM9 CG1161 16-Dec-15 2015_12 "ENSDARG00000025693(tmem9b),ENSDARG00000055757(tmem9)" "ENSMUSG00000031021(Tmem9b),ENSMUSG00000026411(Tmem9)" "ENSG00000116857(TMEM9),ENSG00000175348(TMEM9B)" lethal FBgn0011653 mas masquerade http://flybase.net/reports/FBgn0011653.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008233=peptidase activity" 0006508=proteolysis 0005886=plasma membrane "SPH79, Masquerade, c-SPH79, CG15002" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG15002 16-Dec-15 2015_12 "ENSDARG00000010097(f9),ENSDARG00000029493(zgc:136807),ENSDARG00000011463(LOC100004411),ENSDARG00000034862(f7),ENSDARG00000036041(f2),ENSDARG00000038258(LOC798775)" "ENSMUSG00000031640(Klkb1),ENSMUSG00000031645(F11)" "ENSG00000005001(PRSS22),ENSG00000172382(PRSS27),ENSG00000103355(PRSS33),ENSG00000052344(PRSS8),ENSG00000116176(TPSG1),ENSG00000007038(PRSS21),ENSG00000172236(TPSAB1),ENSG00000197253(TPSB2),ENSG00000189099(PRSS48)" " embryonic stage--pupal stage , embryonic stage | stage 12-17 , embryonic stage | stage 14-17 , embryonic stage | stage 11-13 " " epidermis

, tracheal system

, ventral midline | restricted

" " embryonic stage , embryonic stage | stage 14-17 " " tracheal system

, embryonic/larval tracheal system

, epidermis

" "smell perception defective,taste perception defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "lateral transverse muscle,ventral acute muscle,ventral longitudinal muscle,lateral oblique muscle 1,longitudinal connective,commissure,aCC neuron,pCC neuron,peripheral nervous system" FBgn0039359 RpL27 Ribosomal protein L27 http://flybase.net/reports/FBgn0039359.html protein_coding_gene 0003735=structural constituent of ribosome "0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0051297=centrosome organization, 0006412=translation, 0007052=mitotic spindle organization" 0022625=cytosolic large ribosomal subunit "chr3R:21510055..21510241, RPL27, CG4759, RpL27e" "IPR014722=Ribosomal protein L2 domain 2, IPR018262=Ribosomal protein L27e, conserved site, IPR005824=KOW, IPR008991=Translation protein SH3-like domain, IPR001141=Ribosomal protein L27e" CG4759 16-Dec-15 2015_12 ENSDARG00000015128(rpl27) "YDR471W(RPL27B),YHR010W(RPL27A)" WBGene00004441(rpl-27) ENSXETG00000013647(rpl27) "ENSMUSG00000073640(Rpl27-ps3),ENSMUSG00000063316(Rpl27)" ENSG00000131469(RPL27) lethal DRSC15638 EK -1.495305073 -0.258025489 0.356025419 -4.000192804 1.491885399 4.7943074 FBgn0002779 mo micro-oculus http://flybase.net/reports/FBgn0002779.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" "eye,wing,wing hair" FBgn0003035 par paralog http://flybase.net/reports/FBgn0003035.html gene "0045448=mitotic cell cycle, embryonic, 0007097=nuclear migration, 0048477=oogenesis" "fs(1)A1122[ts], fs(1)A1122" 16-Dec-15 2015_12 "female sterile,maternal effect,recessive,heat sensitive" "ovary,maternal effect,heat sensitive,egg chamber,blastoderm embryo,pole cell,gonad,adult cuticle,wing vein,cleavage nucleus" FBgn0038922 CG6439 http://flybase.net/reports/FBgn0038922.html protein_coding_gene "0004449=isocitrate dehydrogenase (NAD+) activity, 0000287=magnesium ion binding, 0051287=NAD binding" 0006099=tricarboxylic acid cycle "0005875=microtubule associated complex, 0005739=mitochondrion" "FBgn0038922, Idh, isocitrate dehydrogenase, Isocitrate dehydrogenase" "IPR001804=Isocitrate and isopropylmalate dehydrogenases family, IPR004434=Isocitrate dehydrogenase NAD-dependent, IPR024084=Isopropylmalate dehydrogenase-like domain" CG6439 16-Dec-15 2015_12 ENSDARG00000044753(idh3b) WBGene00007993(C37E2.1) ENSXETG00000014969(IDH3B) ENSMUSG00000027406(Idh3b) ENSG00000101365(IDH3B) "lethal,viable,fertile,partially lethal - majority die" FBgn0011166 l(1)DM-3 lethal (1) DM-3 http://flybase.net/reports/FBgn0011166.html FBgn0010204 gene 16-Dec-15 2015_12 lethal FBgn0082688 E(ftz)1815 E(ftz)1815 http://flybase.net/reports/FBgn0082688.html gene 1815 16-Dec-15 2015_12 FBgn0001194 hir heterochromatic recombination inducer http://flybase.net/reports/FBgn0001194.html gene heterochromatic-recombination-inducer 16-Dec-15 2015_12 FBgn0259556 B2011 http://flybase.net/reports/FBgn0259556.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000899 fs(1)M108 female sterile (1) M108 http://flybase.net/reports/FBgn0000899.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0262899 CG43254 http://flybase.net/reports/FBgn0262899.html protein_coding_gene lincRNA.715 CG43254 16-Dec-15 2015_12 FBgn0000026 acj2 abnormal chemosensory jump 2 http://flybase.net/reports/FBgn0000026.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive" FBgn0040513 ë¼B-Ras ë¼B-Ras http://flybase.net/reports/FBgn0040513.html "FBgn0033172, FBgn0064816" protein_coding_gene "0005525=GTP binding, 0005515=protein binding" "0007264=small GTPase mediated signal transduction, 0043124=negative regulation of I-kappaB kinase/NF-kappaB signaling" 0016020=membrane "kappaB-Ras, Q9V4L4-1, B7YZS7, BcDNA:RH38596, CG1669, dkappaB-Ras" "IPR001806=Small GTPase superfamily, IPR020849=Small GTPase superfamily, Ras type, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG1669 16-Dec-15 2015_12 "ENSDARG00000033548(nkiras1),ENSDARG00000052594(nkiras2)" WBGene00009919(F52A8.6) "ENSXETG00000002296(),ENSXETG00000003868(NKIRAS1)" "ENSMUSG00000021772(Nkiras1),ENSMUSG00000017837(Nkiras2)" "ENSG00000197885(NKIRAS1),ENSG00000168256(NKIRAS2)" FBgn0260755 CG42553 http://flybase.net/reports/FBgn0260755.html "FBgn0035163, FBan0013886" protein_coding_gene "CG13886, CT33419" IPR010733=Protein of unknown function DUF1308 CG42553 16-Dec-15 2015_12 FBgn0003590 Su(var)2-3 Suppressor of variegation 2-3 http://flybase.net/reports/FBgn0003590.html gene Su-var(2)3 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0023436 ifa irregular facet http://flybase.net/reports/FBgn0023436.html gene 16-Dec-15 2015_12 visible "pigment cell,ommatidium" FBgn0037636 CG9821 http://flybase.net/reports/FBgn0037636.html "FBgn0051442, FBgn0062018, FBgn0062041" protein_coding_gene "anon-WO0118547.424, Ov29, CG31442, anon-WO0118547.399" IPR026780=Proline-rich nuclear receptor coactivator 1/2 CG9821 16-Dec-15 2015_12 "lethal,viable,fertile,neuroanatomy defective" "presumptive embryonic/larval peripheral nervous system,ventral nerve cord commissure" DRSC16570 EK -0.611206603 0.813672327 -0.525268671 -3.069052823 2.284551098 1.981705373 FBgn0262099 CG42852 http://flybase.net/reports/FBgn0262099.html protein_coding_gene lincRNA.585 CG42852 16-Dec-15 2015_12 FBgn0085256 CG34227 http://flybase.net/reports/FBgn0085256.html protein_coding_gene 0005615=extracellular space CG7738 CG34227 16-Dec-15 2015_12 viable FBgn0266683 CR45173 http://flybase.net/reports/FBgn0266683.html non_protein_coding_gene CR45173 16-Dec-15 2015_12 FBgn0025684 MFS18 Major Facilitator Superfamily Transporter 18 http://flybase.net/reports/FBgn0025684.html FBgn0031605 protein_coding_gene 0015321=sodium-dependent phosphate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "CK02623, BEST:CK02623, CG15438" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG15438 16-Dec-15 2015_12 "ENSDARG00000042954(slc17a9a),ENSDARG00000011049(slc17a9b)" "YGR260W(TNA1),YIL166C()" WBGene00010758(K10H10.1) ENSXETG00000012454(SLC17A9) ENSMUSG00000023393(Slc17a9) ENSG00000101194(SLC17A9) viable FBgn0030314 CG11696 http://flybase.net/reports/FBgn0030314.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus b "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR017956=AT hook, DNA-binding motif, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG11696 16-Dec-15 2015_12 "ENSG00000158805(ZNF276),ENSG00000161914(ZNF653)" FBgn0085276 CG34247 http://flybase.net/reports/FBgn0085276.html protein_coding_gene CG34247 16-Dec-15 2015_12 FBgn0051720 mthl15 methuselah-like 15 http://flybase.net/reports/FBgn0051720.html protein_coding_gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0006950=response to stress" 0005887=integral component of plasma membrane CG31720 "IPR023311=Methuselah ectodomain, domain 2, IPR017981=GPCR, family 2-like, IPR000832=GPCR, family 2, secretin-like, IPR010596=Methuselah, N-terminal domain" CG31720 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" FBgn0265309 CR44282 http://flybase.net/reports/FBgn0265309.html non_protein_coding_gene CR44282 16-Dec-15 2015_12 FBgn0264785 Hph HIF prolyl hydroxylase http://flybase.net/reports/FBgn0264785.html "FBgn0264652, FBgn0086689, FBgn0028167, FBgn0051543, FBgn0037306, FBgn0027674, FBgn0010773, FBgn0037308, FBgn0013577, FBgn0037309" protein_coding_gene "0031543=peptidyl-proline dioxygenase activity, 0031545=peptidyl-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding, 0008270=zinc ion binding, 0005506=iron ion binding" "0007430=terminal branching, open tracheal system, 0006974=cellular response to DNA damage stimulus, 0006611=protein export from nucleus, 0071456=cellular response to hypoxia, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process, 0008104=protein localization, 0030307=positive regulation of cell growth, 0001666=response to hypoxia, 0019511=peptidyl-proline hydroxylation, 0060439=trachea morphogenesis" 0005654=nucleoplasm "l(3)02255, CR31541, HIF-1a prolyl hyroxylase, l(3)S030304, CG31543, hph, anon-EST:Posey69, lethal (3) 82Fe, 0303/04, Dm.egl-9, HIF prolyl 4-hydroxylase, CG2676, Fatiga, l(3)82Fe, lopped, 31543, dPHD2, PHD, dHPH, fatiga, CG1114, CG14665, CG44015, prolyl-4-hydroxylase, fga, dmHPH, dPHD, lethal (3) S030304" "IPR002893=Zinc finger, MYND-type, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR005123=Oxoglutarate/iron-dependent dioxygenase" CG44015 16-Dec-15 2015_12 "ENSDARG00000038996(LOC100329385),ENSDARG00000004632(egln1),ENSDARG00000062562(LOC559569)" WBGene00001178(egl-9) "ENSXETG00000021414(egln1),ENSXETG00000002600(EGLN2)" "ENSMUSG00000031987(Egln1),ENSMUSG00000058709(Egln2),ENSMUSG00000035105(Egln3)" "ENSG00000135766(EGLN1),ENSG00000171570(EGLN2),ENSG00000129521(EGLN3)" FBgn0064155 oosy out of sync http://flybase.net/reports/FBgn0064155.html gene "0035191=nuclear axial expansion, 0007347=regulation of preblastoderm mitotic cell cycle, 0035192=nuclear cortical migration" 16-Dec-15 2015_12 "pole cell,maternal effect,cleavage nucleus,germline clone" FBgn0266535 CR45096 http://flybase.net/reports/FBgn0266535.html non_protein_coding_gene CR45096 16-Dec-15 2015_12 FBgn0053902 His2B:CG33902 His2B:CG33902 http://flybase.net/reports/FBgn0053902.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33902 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000558=Histone H2B" CG33902 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0259111 Ndae1 Na+-driven anion exchanger 1 http://flybase.net/reports/FBgn0259111.html "FBgn0031899, FBgn0021952, FBgn0063801, FBgn0051906" protein_coding_gene "0008510=sodium:bicarbonate symporter activity, 0015106=bicarbonate transmembrane transporter activity, 0015301=anion:anion antiporter activity, 0005452=inorganic anion exchanger activity" "0006814=sodium ion transport, 0006821=chloride transport, 0015992=proton transport, 0015701=bicarbonate transport, 0006820=anion transport" "0016021=integral component of membrane, 0005886=plasma membrane" "Na[+]-driven anion exchanger 1, 153385_at, ndae1, Ndae-1, CG42253, NDAE1, CG4675, CG31906, l(2)k10316, anon-WO0257455.13" "IPR016152=Phosphotransferase/anion transporter, IPR011531=Bicarbonate transporter, C-terminal, IPR003024=Sodium bicarbonate cotransporter, IPR001717=Anion exchange protein, IPR003020=Bicarbonate transporter, eukaryotic, IPR013769=Band 3 cytoplasmic domain" CG42253 16-Dec-15 2015_12 "ENSDARG00000015531(LOC557494),ENSDARG00000063133(LOC798983),ENSDARG00000060303,ENSDARG00000013730(slc4a4a)" WBGene00009920(abts-1) "ENSXETG00000019911(SLC4A7),ENSXETG00000014124(SLC4A8)" "ENSMUSG00000023032(Slc4a8),ENSMUSG00000026904(Slc4a10),ENSMUSG00000021733(Slc4a7)" "ENSG00000033867(SLC4A7),ENSG00000144290(SLC4A10),ENSG00000050438(SLC4A8)" FBgn0053732 snmRNA:430:CR33732 snmRNA:430:CR33732 http://flybase.net/reports/FBgn0053732.html non_protein_coding_gene CR33732 CR33732 16-Dec-15 2015_12 FBgn0000326 clt cricklet http://flybase.net/reports/FBgn0000326.html "FBgn0027353, FBgn0034640" protein_coding_gene 0052689=carboxylic ester hydrolase activity "0060179=male mating behavior, 0007476=imaginal disc-derived wing morphogenesis" "Est-R, anon-57Fb, CG9858, JHE-related, unnamed" "IPR019819=Carboxylesterase type B, conserved site, IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG9858 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" "stress response defective,mating defective,male,recessive" "oocyte,embryonic/larval fat body" FBgn0040486 BobB Brother of Bearded B http://flybase.net/reports/FBgn0040486.html FBgn0026561 gene 0005515=protein binding "Brother of Bearded, Bob-B, Bob" 16-Dec-15 2015_12 FBgn0052233 CG32233 http://flybase.net/reports/FBgn0052233.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0039092 CG16723 http://flybase.net/reports/FBgn0039092.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG16723 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" "partially lethal - majority die,some die during pupal stage" FBgn0260318 GSd317 http://flybase.net/reports/FBgn0260318.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0086302 polk polka dot http://flybase.net/reports/FBgn0086302.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0050372 Asap "ArfGAP with SH3 domain, ankyrin repeat and PH domain" http://flybase.net/reports/FBgn0050372.html "FBgn0033262, FBgn0033263" protein_coding_gene "0005096=GTPase activator activity, 1901981=phosphatidylinositol phosphate binding" "0007264=small GTPase mediated signal transduction, 0043087=regulation of GTPase activity" "0005737=cytoplasm, 0005912=adherens junction" "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1, dAsap, CG2226, Asap1, CG14758, CG30372" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001452=SH3 domain, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR001849=Pleckstrin homology domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR001164=Arf GTPase activating protein" CG30372 16-Dec-15 2015_12 "ENSDARG00000019564(asap2b),ENSDARG00000010181(asap2a),ENSDARG00000029463(si:ch211-160i2.3),ENSDARG00000039729(LOC565859),ENSDARG00000002607(LOC561879),ENSDARG00000021896(asap3)" "ENSXETG00000008265(ASAP2),ENSXETG00000017737(ASAP1)" "ENSMUSG00000052632(Asap2),ENSMUSG00000022377(Asap1)" "ENSG00000153317(ASAP1),ENSG00000151693(ASAP2)" viable FBgn0004429 LysP Lysozyme P http://flybase.net/reports/FBgn0004429.html FBgn0002575 protein_coding_gene 0003796=lysozyme activity 0019730=antimicrobial humoral response "lysozyme, lysP, CG9116" "IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain, IPR019799=Glycoside hydrolase, family 22, conserved site, IPR000974=Glycoside hydrolase, family 22, lysozyme" CG9116 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) adult stage adult salivary gland

viable FBgn0085329 CG34300 http://flybase.net/reports/FBgn0085329.html protein_coding_gene CG34300 16-Dec-15 2015_12 FBgn0065638 l(2)SH0764 lethal (2) SH0764 http://flybase.net/reports/FBgn0065638.html gene l(2)SH2 0764 16-Dec-15 2015_12 "lethal,recessive" FBgn0021998 l(2)k09328 lethal (2) k09328 http://flybase.net/reports/FBgn0021998.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021883 l(2)k13412 lethal (2) k13412 http://flybase.net/reports/FBgn0021883.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038437 Sdhaf3 Succinate dehydrogenase assembly factor 3 http://flybase.net/reports/FBgn0038437.html FBgn0047146 protein_coding_gene "0006979=response to oxidative stress, 0055093=response to hyperoxia, 0050881=musculoskeletal movement, 0006105=succinate metabolic process" 0005739=mitochondrion "CG14898, Sdh7, dSdhaf3, BcDNA:RE23580, sdh7" IPR008381=ACN9 CG14898 16-Dec-15 2015_12 ENSDARG00000036092(zgc:92826) YDR511W(ACN9) WBGene00009139(F25H9.7) ENSMUSG00000042505(Acn9) ENSG00000196636(ACN9) viable DRSC15020 K -0.130708578 0.83602864 0.429028768 0.487062194 0.358231109 4.842556114 FBgn0051887 CG31887 http://flybase.net/reports/FBgn0051887.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024525 l(3)j5E7 lethal (3) j5E7 http://flybase.net/reports/FBgn0024525.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0063909 N::Mmus\Notch1 Notch1 http://flybase.net/reports/FBgn0063909.html engineered_fusion_gene 16-Dec-15 2015_12 neuroanatomy defective "dorsal abdominal cluster,presumptive embryonic/larval peripheral nervous system,S2 cell-line" FBgn0040735 CG16836 http://flybase.net/reports/FBgn0040735.html protein_coding_gene IPR013172=Immune-induced protein Dim CG16836 16-Dec-15 2015_12 viable FBgn0082376 E(GMR-wIR)A28 Enhancer(GMR-wIR)A28 http://flybase.net/reports/FBgn0082376.html gene 16-Dec-15 2015_12 FBgn0004781 Ccp84Ac Ccp84Ac http://flybase.net/reports/FBgn0004781.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCcp84Ac, Ccp, larval cuticle, cuticle cluster 6, cc6, unnamed, CG1327, BG:DS00004.3" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG1327 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12588 K 0.444798667 0.296208733 -0.002042957 0.016943411 1.099519121 -1.759340902 FBgn0036890 CG9368 http://flybase.net/reports/FBgn0036890.html FBgn0062934 protein_coding_gene BcDNA:RH51268 CG9368 16-Dec-15 2015_12 viable DRSC11067 I -0.326665271 1.646061633 -0.168937514 0.147620142 -0.11164128 -0.566697809 FBgn0026168 spnl space-needle http://flybase.net/reports/FBgn0026168.html gene "0007338=single fertilization, 0035041=sperm chromatin decondensation" 16-Dec-15 2015_12 FBgn0028406 Drep4 DNA fragmentation factor-related protein 4 http://flybase.net/reports/FBgn0028406.html protein_coding_gene 0004536=deoxyribonuclease activity 0006309=apoptotic DNA fragmentation "0005634=nucleus, 0005737=cytoplasm" "CG9414, Drep-4, CAD, Drep4, DREP-4, dCAD, Caspase-activated DNase, drep4, Rep4" "IPR003508=CIDE-N domain, IPR015311=Apoptosis, DNA fragmentation factor 40kDa" CG9414 16-Dec-15 2015_12 ENSDARG00000009748(dffb) ENSXETG00000006035(DFFB) ENSMUSG00000029027(Dffb) ENSG00000169598(DFFB) viable FBgn0267888 CR46176 http://flybase.net/reports/FBgn0267888.html pseudogene_attribute CG12717-related CR46176 16-Dec-15 2015_12 FBgn0069998 BG01656 BG01656 http://flybase.net/reports/FBgn0069998.html gene 16-Dec-15 2015_12 stress response defective FBgn0039641 CG14511 http://flybase.net/reports/FBgn0039641.html protein_coding_gene 0005462=UDP-N-acetylglucosamine transmembrane transporter activity 0055085=transmembrane transport 0005797=Golgi medial cisterna IPR013657=UAA transporter CG14511 16-Dec-15 2015_12 YEL004W(YEA4) WBGene00017480(F15B10.1) viable FBgn0259424 EP-650 http://flybase.net/reports/FBgn0259424.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0053377 5SrRNA:CR33377 5SrRNA:CR33377 http://flybase.net/reports/FBgn0053377.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33377 CR33377 16-Dec-15 2015_12 FBgn0004407 DNApol-ë_35 DNA polymerase ë_ 35kD http://flybase.net/reports/FBgn0004407.html "FBgn0000476, FBgn0001962, FBgn0020398, FBgn0053084, FBgn0053650, FBtr0089832, FBpp0088773, FBtr0089833, FBpp0088774" protein_coding_gene 0003887=DNA-directed DNA polymerase activity "0000002=mitochondrial genome maintenance, 0007005=mitochondrion organization, 0006264=mitochondrial DNA replication, 0006261=DNA-dependent DNA replication" "0005739=mitochondrion, 0005760=gamma DNA polymerase complex" "polgamma, PolG, beta subunit, Mitochondrial DNA polymerase accessory subunit, pol gamma35, D-pol gamma-beta, br16, l(2)34De, DNApol-gamma35, lethal(2)34De, accessory subunit of mitochondrial DNA polymerase, mitochondrial gamma polymerase, polgamma-beta, pol gamma-beta, CG33084, MtPolB, DNApol-gamma.35, DNA polymerase -gamma, accessory(beta)subunit, l(2)br16, CG33650, DNApol-gamma, Polgamma, DNA pol-gam.35, DNA polymerase gamma, CG8969, BG:DS00941.9, lethal 16 in the black-reduced region" "IPR004154=Anticodon-binding, IPR027031=Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2" CG33650 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,locomotor behavior defective" "mitochondrion,embryonic/larval central nervous system,mitochondrionb80c1)" FBgn0025007 E(var)102-1 E(var)102-1 http://flybase.net/reports/FBgn0025007.html gene E-102/1 16-Dec-15 2015_12 FBgn0002403 l(3)99Dd lethal (3) 99Dd http://flybase.net/reports/FBgn0002403.html gene 16-Dec-15 2015_12 lethal FBgn0260763 CG42561 http://flybase.net/reports/FBgn0260763.html "FBgn0034260, FBan0014481" protein_coding_gene CG14481 CG42561 16-Dec-15 2015_12 DRSC05676 K 0.01097758 -0.362677984 -0.134144017 0.583906239 1.618992325 -0.442379407 FBgn0265810 CR44599 http://flybase.net/reports/FBgn0265810.html non_protein_coding_gene CR44599 16-Dec-15 2015_12 FBgn0053192 MtnD Metallothionein D http://flybase.net/reports/FBgn0053192.html protein_coding_gene 0046872=metal ion binding "0055065=metal ion homeostasis, 0046688=response to copper ion, 0010038=response to metal ion" "metallothionein, unnamed, CG33192, mtnD" "IPR000966=Metallothionein, family 5, Diptera" CG33192 16-Dec-15 2015_12 DRSC22733 K 0.427786275 0.495561886 1.043114874 -0.407423976 -1.582004459 0.296703443 FBgn0004075 ms(2)35Eb male sterile (2) 35Eb http://flybase.net/reports/FBgn0004075.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 "male sterile,recessive" FBgn0041719 snRNA:U4:25F snRNA:U4:25F http://flybase.net/reports/FBgn0041719.html FBgn0003929 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005687=U4 snRNP "U4-2, U4 snRNA, U4snRNA, CR32998, U4:25F, snRNA:U4, U4-25F, U4, U4 small nuclear RNA, snRNA, U425F, K3, small nuclear RNA U4, dU4" CR32998 16-Dec-15 2015_12 FBgn0022045 l(2)k08306 lethal (2) k08306 http://flybase.net/reports/FBgn0022045.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060655 l(3)S082908a lethal (3) S082908a http://flybase.net/reports/FBgn0060655.html gene 0829/08 16-Dec-15 2015_12 "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0053465 CG33465 http://flybase.net/reports/FBgn0053465.html FBgn0082660 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CR33465, HDC06631, BP1080, unnamed" "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG33465 16-Dec-15 2015_12 "ENSDARG00000004748(zgc:100868),ENSDARG00000052905(zgc:165423)" FBgn0044324 Chro Chromator http://flybase.net/reports/FBgn0044324.html "FBgn0025218, FBgn0037201" protein_coding_gene 0042393=histone binding "0007052=mitotic spindle organization, 0051276=chromosome organization, 0051310=metaphase plate congression, 0006325=chromatin organization, 0007552=metamorphosis, 0007059=chromosome segregation, 0007094=mitotic spindle assembly checkpoint" "0005813=centrosome, 0005705=polytene chromosome interband, 0005634=nucleus, 0005819=spindle, 0005700=polytene chromosome" "Chriz, Chiz, Chr, Chro(Chriz), CHRIZ/CHRO, Chromobox protein interacting with Z4, Chromator, anon-fast-evolving-2E3, CHRO, CHRIZ, Chromo domain protein interacting with Z4, unnamed, anon-EST:fe2E3, CG10712" "IPR023780=Chromo domain, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain" CG10712 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,size defective,lethal - all die before end of larval stage,some die during third instar larval stage" "abdominal temporary eclosion muscle DA,A1-7 dorsal oblique muscle,wing,embryonic/larval neuroblast,imaginal disc,embryonic/larval brain,spindle | third instar larval stage,polytene chromosome" DRSC11630 EK -1.202313509 -1.343129555 -1.505271314 -1.25953784 2.164606305 0.181784419 FBgn0036324 CG12520 http://flybase.net/reports/FBgn0036324.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBgn0036324 IPR001810=F-box domain CG12520 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0265730 CR44537 http://flybase.net/reports/FBgn0265730.html non_protein_coding_gene "incRNA.408, lincRNA.408" CR44537 16-Dec-15 2015_12 FBgn0050027 CG30027 http://flybase.net/reports/FBgn0050027.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264384 CR43836 http://flybase.net/reports/FBgn0264384.html non_protein_coding_gene CR43836 16-Dec-15 2015_12 FBgn0263539 mir-4978 mir-4978 stem loop http://flybase.net/reports/FBgn0263539.html miRNA_gene "CR43524, dme-mir-4978" CR43524 16-Dec-15 2015_12 FBgn0264469 CR43877 http://flybase.net/reports/FBgn0264469.html non_protein_coding_gene CR43877 16-Dec-15 2015_12 FBgn0267524 2SrRNA:CR45864 2S ribosomal RNA:CR45864 http://flybase.net/reports/FBgn0267524.html rRNA_gene CR45864 CR45864 16-Dec-15 2015_12 FBgn0022311 l(1)J30.4 lethal (1) J30.4 http://flybase.net/reports/FBgn0022311.html gene J30.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0060926 l(3)S042203b lethal (3) S042203b http://flybase.net/reports/FBgn0060926.html gene 0422/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0020060 E(spl)m8-HLH::h E(spl)::h http://flybase.net/reports/FBgn0020060.html engineered_fusion_gene E(spl)::h 16-Dec-15 2015_12 "lethal,female" FBgn0061096 l(3)S009911 lethal (3) S009911 http://flybase.net/reports/FBgn0061096.html gene 0099/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262509 nrm neuromusculin http://flybase.net/reports/FBgn0262509.html "FBgn0005629, FBan0008779, FBgn0084015, FBan0041452, FBgn0052458, FBan0032458" protein_coding_gene "0007155=cell adhesion, 0008039=synaptic target recognition" 0005886=plasma membrane "CG8779, CG43079, Neuromusculin, CT16082, neuromusculin, CG32458, CG41452" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR013106=Immunoglobulin V-set domain, IPR013098=Immunoglobulin I-set, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain" CG43079 16-Dec-15 2015_12 "ENSDARG00000045875,ENSDARG00000043426,ENSDARG00000062309,ENSDARG00000034910,ENSDARG00000039096(si:dkey-24p1.1),ENSDARG00000055245" ENSMUSG00000030577(Cd22) " embryonic stage | stage >=15 , embryonic stage | stage 9-12 , embryonic stage | stage 9 " " larval muscle system

, embryonic peripheral nervous system

, sensory mother cell

" FBgn0062526 l(3)88EFf lethal (3) 88EFf http://flybase.net/reports/FBgn0062526.html gene 16-Dec-15 2015_12 lethal FBgn0005056 fs(2)OW102 female sterile (2) OW102 http://flybase.net/reports/FBgn0005056.html gene 16-Dec-15 2015_12 FBgn0266261 CG44956 http://flybase.net/reports/FBgn0266261.html protein_coding_gene CG44956 16-Dec-15 2015_12 FBgn0044073 E(rst)J25 E(rst)J25 http://flybase.net/reports/FBgn0044073.html gene 0001745=compound eye morphogenesis J25 16-Dec-15 2015_12 FBgn0267084 CR45528 http://flybase.net/reports/FBgn0267084.html non_protein_coding_gene CR45528 16-Dec-15 2015_12 FBgn0034425 CG11906 http://flybase.net/reports/FBgn0034425.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" 0006357=regulation of transcription from RNA polymerase II promoter 0005634=nucleus "Gene 6, 11906" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR029795=SNAIL family" CG11906 16-Dec-15 2015_12 "viable,fertile" FBgn0266513 s-523.2 http://flybase.net/reports/FBgn0266513.html gene 16-Dec-15 2015_12 FBgn0034950 Pask PAS kinase http://flybase.net/reports/FBgn0034950.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" 0006468=protein phosphorylation "0005634=nucleus, 0005737=cytoplasm" "CG3105, pask" "IPR000014=PAS domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG3105 16-Dec-15 2015_12 ENSMUSG00000026274(Pask) ENSG00000115687(PASK) viable FBgn0262752 Mst77Y-3ë¬ Male-specific pseudogene 77Y 3 http://flybase.net/reports/FBgn0262752.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0019733 l(1)A13 lethal (1) A13 http://flybase.net/reports/FBgn0019733.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010622 DCTN3-p24 "Dynactin 3, p24 subunit" http://flybase.net/reports/FBgn0010622.html FBgn0034813 protein_coding_gene "0035206=regulation of hemocyte proliferation, 0007018=microtubule-based movement" 0005869=dynactin complex "lethal-(2)06 496, p22/p24, dynactin, p24 subunit, p24, l(2)06 496, CG9893, l(2)06496, lethal (2) 06496" IPR009991=Dynactin subunit p22 CG9893 16-Dec-15 2015_12 "lethal,recessive" FBgn0060461 l(3)S115510b lethal (3) S115510b http://flybase.net/reports/FBgn0060461.html gene 1155/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0052398 CG32398 http://flybase.net/reports/FBgn0052398.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0040329 EY3-2 EY3-2 http://flybase.net/reports/FBgn0040329.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000124 Ars-region2 Autonomous replicating sequence region 2 http://flybase.net/reports/FBgn0000124.html region "DmARS-2, Ars2, Ars sequence 2" 16-Dec-15 2015_12 FBgn0034162 CG6426 http://flybase.net/reports/FBgn0034162.html FBgn0047058 protein_coding_gene 0003796=lysozyme activity 0032504=multicellular organism reproduction 0005615=extracellular space "n(2)k04810, l(2)k04810, BcDNA:RH01665" IPR008597=Destabilase CG6426 16-Dec-15 2015_12 "WBGene00017691(ilys-5),WBGene00016670(ilys-3),WBGene00016669(ilys-2),WBGene00016668(ilys-1),WBGene00016958(ilys-4)" "viable,fertile" FBgn0036469 CG18649 http://flybase.net/reports/FBgn0036469.html FBgn0047060 protein_coding_gene BcDNA:RE73239 CG18649 16-Dec-15 2015_12 viable DRSC10334 IK 1.514783743 1.90338617 0.33761691 -0.227576919 -0.502353603 1.602338918 FBgn0035299 CG11815 http://flybase.net/reports/FBgn0035299.html protein_coding_gene CG11815 16-Dec-15 2015_12 viable FBgn0038608 WRNexo WRN exonuclease http://flybase.net/reports/FBgn0038608.html protein_coding_gene "0008310=single-stranded DNA 3'-5' exodeoxyribonuclease activity, 0003676=nucleic acid binding, 0008408=3'-5' exonuclease activity, 0008311=double-stranded DNA 3'-5' exodeoxyribonuclease activity" "0045950=negative regulation of mitotic recombination, 0000738=DNA catabolic process, exonucleolytic" 0005634=nucleus "CG7670, DmWRNexo" "IPR012337=Ribonuclease H-like domain, IPR002562=3'-5' exonuclease domain" CG7670 16-Dec-15 2015_12 "viable,fertile,female sterile,male fertile,chemical sensitive,partially lethal - majority die,some die during pupal stage" DRSC16278 K 0.267051824 0.122949397 0.463713755 0.412671518 1.965578096 -1.673582142 FBgn0000935 fs(2)A5 female sterile (2) A5 http://flybase.net/reports/FBgn0000935.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0053983 obst-H obstructor-H http://flybase.net/reports/FBgn0053983.html "FBgn0036506, FBgn0036507" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "CG7973(short), CG17014, CG7973, CG33983, FBgn0036507" IPR002557=Chitin binding domain CG33983 16-Dec-15 2015_12 viable FBgn0065182 l(3)SH001 lethal (3) SH001 http://flybase.net/reports/FBgn0065182.html gene l(2)SH3 001 16-Dec-15 2015_12 "lethal,recessive" FBgn0266589 CR45114 http://flybase.net/reports/FBgn0266589.html non_protein_coding_gene lincRNA.452 CR45114 16-Dec-15 2015_12 FBgn0022075 l(2)k07713 lethal (2) k07713 http://flybase.net/reports/FBgn0022075.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021917 l(2)k11325 lethal (2) k11325 http://flybase.net/reports/FBgn0021917.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069171 mcl(3)Z0589 mcl(3)Z0589 http://flybase.net/reports/FBgn0069171.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0016861 l(1)N9 lethal (1) N9 http://flybase.net/reports/FBgn0016861.html gene N9 16-Dec-15 2015_12 "lethal,recessive" FBgn0020774 vi vena interrupta http://flybase.net/reports/FBgn0020774.html gene 16-Dec-15 2015_12 FBgn0265888 CR44677 http://flybase.net/reports/FBgn0265888.html non_protein_coding_gene lincRNA.626 CR44677 16-Dec-15 2015_12 FBgn0067045 U12 U12 http://flybase.net/reports/FBgn0067045.html gene 16-Dec-15 2015_12 "visible,lethal" chaeta FBgn0004550 l(4)102CDv lethal (4) 102CDv http://flybase.net/reports/FBgn0004550.html gene l(4)37 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262709 ifm(2)RS2 http://flybase.net/reports/FBgn0262709.html gene "0060361=flight, 0007527=adult somatic muscle development" 16-Dec-15 2015_12 "flightless,recessive" dorsal medial muscle FBgn0043375 EP1216b EP1216b http://flybase.net/reports/FBgn0043375.html gene 16-Dec-15 2015_12 visible "macrochaeta,ectopic,trichogen cell,tormogen cell" FBgn0067661 pup poulpe http://flybase.net/reports/FBgn0067661.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 "egg chamber,germline clone" FBgn0058244 CG40244 http://flybase.net/reports/FBgn0058244.html FBan0040244 protein_coding_gene 16-Dec-15 2015_12 DRSC21814 IEK 5.560697221 -2.22747849 10.01167853 -0.067034215 -7.683167223 -5.327016062 FBgn0051767 CR31767 http://flybase.net/reports/FBgn0051767.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0060725 l(3)S068016 lethal (3) S068016 http://flybase.net/reports/FBgn0060725.html gene 0680/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040493 grsm granny smith http://flybase.net/reports/FBgn0040493.html "FBgn0038096, FBgn0069190" protein_coding_gene "0030145=manganese ion binding, 0004177=aminopeptidase activity, 0008235=metalloexopeptidase activity" 0006508=proteolysis 0005737=cytoplasm "BcDNA:LD41548, l(3)c00064, granny-smith, granny smith, Leucyl-aminopeptidase, lethal (3) c00064, unnamed, aminopeptidase, CG7340, grsm" "IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal" CG7340 16-Dec-15 2015_12 ENSDARG00000012871(npepl1) WBGene00002249(lap-1) ENSMUSG00000039263(Npepl1) ENSG00000215440(NPEPL1) "lethal,recessive,viable,fertile" FBgn0036159 CG7557 http://flybase.net/reports/FBgn0036159.html FBgn0044586 protein_coding_gene anon-WO0140519.44 IPR027417=P-loop containing nucleoside triphosphate hydrolase CG7557 16-Dec-15 2015_12 ENSMUSG00000059555(A830007P12Rik) viable FBgn0004069 fs(2)mel3 female sterile (2) maternal effect lethal 3 http://flybase.net/reports/FBgn0004069.html gene mel 3 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "chorion | maternal effect,dorsal appendage,maternal effect,egg,pole cell,amnioproctodeal invagination,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,cephalic furrow,abdominal segment 2,abdominal segment 3,abdominal segment 4,embryonic/larval posterior spiracle,filzkorper,embryonic head" FBgn0014924 anon-72ABh anon-72ABh http://flybase.net/reports/FBgn0014924.html gene 16-Dec-15 2015_12 FBgn0004441 prd8 paired-like 8 http://flybase.net/reports/FBgn0004441.html gene PRD gene 8 16-Dec-15 2015_12 " oogenesis stage , embryonic stage | <8-12 hr " FBgn0033677 CG8321 http://flybase.net/reports/FBgn0033677.html protein_coding_gene IPR029383=ADP-ribosylation factor-like protein 6-interacting protein 6 CG8321 16-Dec-15 2015_12 "learning defective,viable" FBgn0039038 CG6688 http://flybase.net/reports/FBgn0039038.html protein_coding_gene 0008270=zinc ion binding "0007275=multicellular organismal development, 0006511=ubiquitin-dependent protein catabolic process" 0005634=nucleus "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR004162=E3 ubiquitin-protein ligase SIN-like, IPR001478=PDZ domain, IPR001841=Zinc finger, RING-type" CG6688 16-Dec-15 2015_12 "viable,fertile" FBgn0065073 snoRNA:229 snoRNA:229 http://flybase.net/reports/FBgn0065073.html FBgn0053684 snoRNA_gene 0030555=RNA modification guide activity 0005730=nucleolus "snoR229, Dm-229, SnoR229, DmOr_cd3, chr2R:18581419..18581570, CR33684" CR33684 16-Dec-15 2015_12 FBgn0029898 CG14439 http://flybase.net/reports/FBgn0029898.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG14439 16-Dec-15 2015_12 "ENSXETG00000020519(),ENSXETG00000020520()" "viable,fertile" FBgn0069416 JJF144 JJF144 http://flybase.net/reports/FBgn0069416.html gene 16-Dec-15 2015_12 stress response defective FBgn0260005 wtrw water witch http://flybase.net/reports/FBgn0260005.html "FBgn0259486, FBgn0051284, FBgn0037527, FBgn0037528" protein_coding_gene "0005261=cation channel activity, 0005262=calcium channel activity" "0034220=ion transmembrane transport, 0006816=calcium ion transport, 0007605=sensory perception of sound, 0009270=response to humidity, 0006812=cation transport" 0034703=cation channel complex "CG31284, CG10409, CG17817, water witch, trpA3, 153412_at, CT29234, dTRPA3, Wtrw, Waterwitch, waterwitch" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR030288=Transient receptor potential ankyrin 1 channel, IPR005821=Ion transport domain" CG31284 16-Dec-15 2015_12 FBgn0051952 CG31952 http://flybase.net/reports/FBgn0051952.html "FBgn0031532, FBgn0061453" protein_coding_gene "CG15413, BcDNA:AT14709" CG31952 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" DRSC21997 IK -1.550360148 0.05717731 -1.285798533 -1.056348261 0.418455833 1.683162186 FBgn0061005 l(3)S026437 lethal (3) S026437 http://flybase.net/reports/FBgn0061005.html gene 0264/37 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266145 CR44851 http://flybase.net/reports/FBgn0266145.html non_protein_coding_gene CR44851 16-Dec-15 2015_12 FBgn0000853 fs(1)M43 female sterile (1) M43 http://flybase.net/reports/FBgn0000853.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage" "egg,maternal effect" FBgn0032303 CG6508 http://flybase.net/reports/FBgn0032303.html protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis "IPR001461=Aspartic peptidase, IPR021109=Aspartic peptidase domain, IPR001969=Aspartic peptidase, active site" CG6508 16-Dec-15 2015_12 "ENSMUSG00000023987(Pgc),ENSMUSG00000004552(Ctse)" "ENSG00000204973,ENSG00000172647,ENSG00000180860,ENSG00000196188(CTSE),ENSG00000096088(PGC)" viable FBgn0030582 CG14411 http://flybase.net/reports/FBgn0030582.html protein_coding_gene "0004438=phosphatidylinositol-3-phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0050829=defense response to Gram-negative bacterium, 0046856=phosphatidylinositol dephosphorylation" 0005737=cytoplasm "IPR010569=Myotubularin-like phosphatase domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR030564=Myotubularin family, IPR022587=Myotubularin-related 12-like C-terminal domain, IPR029021=Protein-tyrosine phosphatase-like" CG14411 16-Dec-15 2015_12 "ENSDARG00000010601(zgc:153233),ENSDARG00000059817(mtmr12)" "ENSXETG00000016494(MTMR10),ENSXETG00000015585(MTMR12),ENSXETG00000011034(MTMR11)" "ENSMUSG00000030522(Mtmr10),ENSMUSG00000039458(Mtmr12)" "ENSG00000166912(MTMR10),ENSG00000150712(MTMR12)" viable FBgn0023202 Hci Hci http://flybase.net/reports/FBgn0023202.html gene DHCI 16-Dec-15 2015_12 FBgn0028229 l(3)S004624 lethal (3) S004624 http://flybase.net/reports/FBgn0028229.html FBgn0061029 gene "0475/22, 0245/33, l(3)S024533a, l(3)S047522" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0264276 Su(Mir)2 http://flybase.net/reports/FBgn0264276.html gene 16-Dec-15 2015_12 "viable,female sterile,lethal" FBgn0267775 CR46106 http://flybase.net/reports/FBgn0267775.html non_protein_coding_gene CR46106 16-Dec-15 2015_12 FBgn0069106 mus318 mutagen-sensitive 318 http://flybase.net/reports/FBgn0069106.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0060570 l(3)S096003b lethal (3) S096003b http://flybase.net/reports/FBgn0060570.html gene 0960/03 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0065352 l(2)SH1797 lethal (2) SH1797 http://flybase.net/reports/FBgn0065352.html gene l(2)SH2 1797 16-Dec-15 2015_12 "lethal,recessive" FBgn0036390 CG13738 http://flybase.net/reports/FBgn0036390.html FBgn0062986 protein_coding_gene BcDNA:RE61257 CG13738 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC10065 IE 0.413682796 -2.651382887 0.34192245 -1.669579992 -0.781042733 0.202180698 FBgn0263968 nonC no-on-and-no-off transient C http://flybase.net/reports/FBgn0263968.html "FBgn0002959, FBgn0052743, FBgn0024193, FBgn0026002, FBgn0029908, FBgn0029910, FBgn0046599" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0016246=RNA interference, 0035195=gene silencing by miRNA, 0048489=synaptic vesicle transport, 0007274=neuromuscular synaptic transmission, 0046777=protein autophosphorylation, 0050808=synapse organization, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0018105=peptidyl-serine phosphorylation, 0016310=phosphorylation" "0005737=cytoplasm, 0005634=nucleus" "anon-WO0170980.133, anon-EST:Liang-1.24, CG4555, CG4549, Smg1, rst(1a)cyr, CG32743, smg1, no on or off transient C, Smg, resistance 1a cyromazine, SMG1, FRAP-related, dSmg1, clone 1.24" "IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR014009=PIK-related kinase, IPR016024=Armadillo-type fold, IPR011009=Protein kinase-like domain, IPR003152=FATC domain" CG32743 16-Dec-15 2015_12 ENSDARG00000054570 WBGene00004879(smg-1) ENSMUSG00000030655(Smg1) ENSG00000157106(SMG1) FBgn0061512 frogger\polyprotein polyprotein http://flybase.net/reports/FBgn0061512.html transposable_element_gene "IPR013103=Reverse transcriptase, RNA-dependent DNA polymerase" 16-Dec-15 2015_12 FBgn0042110 CG18765 http://flybase.net/reports/FBgn0042110.html protein_coding_gene "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG18765 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0086038 snoRNA:Me28S-C1237 http://flybase.net/reports/FBgn0086038.html snoRNA_gene "Me28S-Cm1237, CR34667" CR34667 16-Dec-15 2015_12 FBgn0259848 Su(Ste):CR42417 Su(Ste):CR42417 http://flybase.net/reports/FBgn0259848.html non_protein_coding_gene CR42417 CR42417 16-Dec-15 2015_12 FBgn0029050 l(1)G0462 lethal (1) G0462 http://flybase.net/reports/FBgn0029050.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261565 Lmpt Limpet http://flybase.net/reports/FBgn0261565.html "FBgn0053256, FBgn0036673, FBgn0036672, FBgn0036674, FBgn0036675, FBgn0052171, FBgn0063025" protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity" 0050832=defense response to fungus 0005634=nucleus "CG32171, CG11916, limpet, CG9959, CG33256, CG11915, CG11914, CG42679, BcDNA:RE37250, lmpt" "IPR010442=PET domain, IPR001781=Zinc finger, LIM-type" CG42679 16-Dec-15 2015_12 WBGene00006407(lim-9) DRSC22921 I 1.762778912 -0.415694471 -0.52595675 -0.322251979 0.200986473 -0.647340685 FBgn0014016 Rbp13 RNA-binding protein 13 http://flybase.net/reports/FBgn0014016.html gene 0003729=mRNA binding "RBP, Rbp" 16-Dec-15 2015_12 FBgn0004554 Edg91 Ecdysone-dependent gene 91 http://flybase.net/reports/FBgn0004554.html protein_coding_gene 0008011=structural constituent of pupal chitin-based cuticle "CG7539, EDG91, EDG-91" CG7539 16-Dec-15 2015_12 viable FBgn0013613 l(3)L1042 lethal (3) L1042 http://flybase.net/reports/FBgn0013613.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060781 l(3)S060402 lethal (3) S060402 http://flybase.net/reports/FBgn0060781.html gene 0604/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0069985 BG02201 BG02201 http://flybase.net/reports/FBgn0069985.html gene 16-Dec-15 2015_12 stress response defective FBgn0082576 Curled_like Curled like http://flybase.net/reports/FBgn0082576.html gene Cul 16-Dec-15 2015_12 "visible,dominant" wing FBgn0263465 snoRNA:kis-a http://flybase.net/reports/FBgn0263465.html snoRNA_gene snoCD_02 CR43580 16-Dec-15 2015_12 FBgn0266020 CR44785 http://flybase.net/reports/FBgn0266020.html non_protein_coding_gene lincRNA.210 CR44785 16-Dec-15 2015_12 FBgn0032448 CG5781 http://flybase.net/reports/FBgn0032448.html protein_coding_gene 0007067=mitotic nuclear division "0005819=spindle, 0005874=microtubule" IPR009675=TPX2 CG5781 16-Dec-15 2015_12 viable FBgn0032424 CG17010 http://flybase.net/reports/FBgn0032424.html protein_coding_gene 0004747=ribokinase activity 0006014=D-ribose metabolic process "0005634=nucleus, 0005737=cytoplasm" "IPR029056=Ribokinase-like, IPR002139=Ribokinase, IPR011611=Carbohydrate kinase PfkB" CG17010 16-Dec-15 2015_12 ENSDARG00000019877(rbks) YCR036W(RBK1) WBGene00008548(F07A11.5) ENSXETG00000010187(RBKS) ENSMUSG00000029136(Rbks) ENSG00000171174(RBKS) FBgn0000222 brw broader wing http://flybase.net/reports/FBgn0000222.html gene 16-Dec-15 2015_12 "viable,male,poor,male sterile,visible,recessive" wing FBgn0010890 l(3)06465 lethal (3) 06465 http://flybase.net/reports/FBgn0010890.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003653 svs shortened veins http://flybase.net/reports/FBgn0003653.html gene shv 16-Dec-15 2015_12 "female sterile,male fertile,viable,male,reduced,visible" "wing,wing vein,wing vein L4,eye,posterior crossvein" FBgn0029170 TwdlT TweedleT http://flybase.net/reports/FBgn0029170.html FBgn0039477 protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix "GCR(ich), CG5812" IPR004145=Domain of unknown function DUF243 CG5812 16-Dec-15 2015_12 viable FBgn0014219 l(2)31Db lethal (2) 31Db http://flybase.net/reports/FBgn0014219.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033330 CG8746 http://flybase.net/reports/FBgn0033330.html protein_coding_gene CG8746 16-Dec-15 2015_12 viable FBgn0004049 yrt yurt http://flybase.net/reports/FBgn0004049.html "FBgn0000466, FBgn0002363, FBgn0038155" protein_coding_gene 0008092=cytoskeletal protein binding "0042462=eye photoreceptor cell development, 0007390=germ-band shortening, 0046665=amnioserosa maintenance, 0045198=establishment of epithelial cell apical/basal polarity, 0008258=head involution, 0007391=dorsal closure, 0035088=establishment or maintenance of apical/basal cell polarity" "0019898=extrinsic component of membrane, 0005915=zonula adherens, 0005737=cytoplasm, 0005856=cytoskeleton, 0005918=septate junction, 0016323=basolateral plasma membrane" "dlhB, CG9764, l(3)E19, lethal(3)87Ek, Nbl4, Yrt, Yurt, m112, l(3)m112, dorsal holes B, l(3)87Ek" "IPR000798=Ezrin/radixin/moesin-like, IPR019747=FERM conserved site, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749=Band 4.1 domain, IPR014847=FERM adjacent (FA), IPR000299=FERM domain, IPR018979=FERM, N-terminal, IPR029071=Ubiquitin-related domain, IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR018980=FERM, C-terminal PH-like domain" CG9764 16-Dec-15 2015_12 ENSDARG00000032324(LOC100007299) WBGene00001489(frm-2) "ENSMUSG00000028434(Epb4.1l4b),ENSMUSG00000026383(Epb4.1l5)" "ENSG00000095203(EPB41L4B),ENSG00000115109(EPB41L5)" "lethal,cell polarity defective,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" "macrochaeta,ommatidium,epidermis,germline clone,trachea,embryonic/first instar larval cuticle,eye photoreceptor cell stalk,eye photoreceptor cell,conditional,rhabdomere of eye photoreceptor cell,adherens junction,embryonic head,amnioserosa,embryo,dorsal,posterior,dorsal ridge,embryonic/larval cuticle" FBgn0259369 EP-596 http://flybase.net/reports/FBgn0259369.html gene 16-Dec-15 2015_12 "visible,lethal" "wing,wing margin" FBgn0036852 CG14083 http://flybase.net/reports/FBgn0036852.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260327 GSd031 http://flybase.net/reports/FBgn0260327.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0085606 CG41310 http://flybase.net/reports/FBgn0085606.html FBan0041310 protein_coding_gene 16-Dec-15 2015_12 FBgn0019797 l(1)08 lethal (1) 08 http://flybase.net/reports/FBgn0019797.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0000700 fltF flight defective F http://flybase.net/reports/FBgn0000700.html gene 16-Dec-15 2015_12 "jumping defective,flight defective" FBgn0038858 CG5793 http://flybase.net/reports/FBgn0038858.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process FBgn0038858 "IPR011234=Fumarylacetoacetase, C-terminal-related" CG5793 16-Dec-15 2015_12 ENSDARG00000031657(fahd1) YNL168C(FMP41) WBGene00022798(ZK688.3) ENSMUSG00000045316(Fahd1) ENSG00000180185(FAHD1) viable FBgn0262875 CG43230 http://flybase.net/reports/FBgn0262875.html protein_coding_gene CG43230 16-Dec-15 2015_12 FBgn0028173 l(3)S026430 lethal (3) S026430 http://flybase.net/reports/FBgn0028173.html gene 0264/30 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0265146 CR44215 http://flybase.net/reports/FBgn0265146.html pseudogene_attribute CR44215 16-Dec-15 2015_12 FBgn0014242 l(2)32Ac lethal (2) 32Ac http://flybase.net/reports/FBgn0014242.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002221 l(3)68Aa lethal (3) 68Aa http://flybase.net/reports/FBgn0002221.html gene l(3)C288 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage" macrochaeta FBgn0267193 CR45633 http://flybase.net/reports/FBgn0267193.html non_protein_coding_gene CR45633 16-Dec-15 2015_12 FBgn0037852 Tpc1 Thiamine pyrophosphate carrier protein 1 http://flybase.net/reports/FBgn0037852.html protein_coding_gene "0022857=transmembrane transporter activity, 0015619=thiamine pyrophosphate-transporting ATPase activity" "0055085=transmembrane transport, 0006839=mitochondrial transport, 0030974=thiamine pyrophosphate transport" 0031966=mitochondrial membrane "thiamine pyrophosphate carrier protein, DmTpc1, CG6608" "IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain" CG6608 16-Dec-15 2015_12 ENSDARG00000038942 WBGene00016588(C42C1.10) ENSXETG00000025476(slc25a19) ENSMUSG00000020744(Slc25a19) ENSG00000125454(SLC25A19) "visible,viable" wing DRSC15614 I -0.252611386 -2.59170152 -0.350131061 -1.220479227 0.552369677 0.253307087 FBgn0035179 CG12038 http://flybase.net/reports/FBgn0035179.html protein_coding_gene unnamed "IPR029244=FAM69, N-terminal, IPR022049=FAM69, protein-kinase domain" CG12038 16-Dec-15 2015_12 ENSDARG00000045457(fam69c) WBGene00016902(C53D5.1) ENSXETG00000023563(FAM69C) ENSMUSG00000047992(Fam69c) ENSG00000187773(FAM69C) FBgn0065278 l(2)SH2044 lethal (2) SH2044 http://flybase.net/reports/FBgn0065278.html gene l(2)SH2 2044 16-Dec-15 2015_12 "lethal,recessive" FBgn0020261 pcm pacman http://flybase.net/reports/FBgn0020261.html protein_coding_gene "0004534=5'-3' exoribonuclease activity, 0003676=nucleic acid binding" "0007476=imaginal disc-derived wing morphogenesis, 0046529=imaginal disc fusion, thorax closure, 0042060=wound healing, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0010603=regulation of cytoplasmic mRNA processing body assembly, 0016246=RNA interference, 0007391=dorsal closure, 0034428=nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3', 0007283=spermatogenesis, 0009267=cellular response to starvation, 0006401=RNA catabolic process, 0007369=gastrulation" "0000932=cytoplasmic mRNA processing body, 0005737=cytoplasm" "Xrn1, DmXrn1, XRN1, Xrn1p, XRN1/pcm, CG3291, Pcm, Pacman" "IPR004859=Putative 5-3 exonuclease, IPR027073=5'-3' exoribonuclease, IPR016494=5'-3' exoribonuclease 1" CG3291 16-Dec-15 2015_12 YGL173C(KEM1) WBGene00012730(xrn-1) ENSMUSG00000032410(Xrn1) ENSG00000114127(XRN1) " adult stage && oogenesis stage , adult stage | male , adult stage | female , embryonic stage | 0-8hr , embryonic stage | stage 1-7 " " nurse cell

, oocyte

,

ubiquitous " "visible,partially lethal - majority die,some die during pupal stage,viable,wound healing defective,fertile,reduced,female semi-sterile,recessive,cold sensitive,partially lethal - majority live" "mesothoracic tergum,testis,spermatozoon,egg chamber,wing,cold sensitive,posterior wing margin,metathoracic femur,cytoplasmic mRNA processing body | cold sensitive,pupal thorax,embryonic/first instar larval cuticle,cytoplasmic mRNA processing body | cold sensitiveJA27)" FBgn0028700 RfC38 Replication factor C 38kD subunit http://flybase.net/reports/FBgn0028700.html FBgn0027894 protein_coding_gene "0003689=DNA clamp loader activity, 0016887=ATPase activity" "0022008=neurogenesis, 0006260=DNA replication" "0005663=DNA replication factor C complex, 0005875=microtubule associated complex" "n(2)k13807, DNA replication factor, 38k subunit, BcDNA:LD06837, DmRFC5, Rfc38, l(2)k13807, CG6258, l(2)rfc38" "IPR013748=Replication factor C, C-terminal, IPR003593=AAA+ ATPase domain, IPR008921=DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6258 16-Dec-15 2015_12 ENSDARG00000055969(rfc3) YBR087W(RFC5) WBGene00004339(rfc-3) ENSXETG00000016918(RFC3) ENSMUSG00000033970(Rfc3) ENSG00000133119(RFC3) "lethal,recessive,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0065814 l(2)SH0381 lethal (2) SH0381 http://flybase.net/reports/FBgn0065814.html gene l(2)SH2 0381 16-Dec-15 2015_12 "lethal,recessive" FBgn0259965 Sfp35C Seminal fluid protein 35C http://flybase.net/reports/FBgn0259965.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 35C, CG42475" CG42475 16-Dec-15 2015_12 FBgn0260278 GSd098 http://flybase.net/reports/FBgn0260278.html gene 16-Dec-15 2015_12 lethal FBgn0035027 CG3511 http://flybase.net/reports/FBgn0035027.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding" 0071013=catalytic step 2 spliceosome "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR001680=WD40 repeat, IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase" CG3511 16-Dec-15 2015_12 WBGene00000891(cyn-15) ENSXETG00000000454(PPWD1) ENSMUSG00000021713(Ppwd1) ENSG00000113593(PPWD1) "large body,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" mesothoracic tergum FBgn0030870 CG6398 http://flybase.net/reports/FBgn0030870.html protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 0060857=establishment of glial blood-brain barrier" "0045179=apical cortex, 0016021=integral component of membrane, 0005918=septate junction" IPR004031=PMP-22/EMP/MP20/Claudin superfamily CG6398 16-Dec-15 2015_12 "ENSDARG00000039951,ENSDARG00000027394(LOC559304),ENSDARG00000006747(zgc:92710),ENSDARG00000004577(zgc:194665),ENSDARG00000020758(tmem178)" WBGene00018743(F53B3.5) ENSG00000080822(CLDND1) viable FBgn0259860 Su(Ste):CR42429 Su(Ste):CR42429 http://flybase.net/reports/FBgn0259860.html non_protein_coding_gene "SuSte{}RR42263, CR42429" CR42429 16-Dec-15 2015_12 FBgn0263448 CR43471 http://flybase.net/reports/FBgn0263448.html non_protein_coding_gene CR43471 16-Dec-15 2015_12 FBgn0024629 l(2)k15211 lethal (2) k15211 http://flybase.net/reports/FBgn0024629.html gene 152/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0031601 Dim1 Dim1 http://flybase.net/reports/FBgn0031601.html FBgn0047167 protein_coding_gene 0005515=protein binding "0022008=neurogenesis, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0000398=mRNA splicing, via spliceosome" "0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0005682=U5 snRNP" "U5-15kD, CG3058, BcDNA:RE13747" "IPR004123=Dim1 family, IPR012336=Thioredoxin-like fold" CG3058 16-Dec-15 2015_12 ENSDARG00000036190(txnl4a) YPR082C(DIB1) ENSXETG00000014807(txnl4a) ENSMUSG00000057130 ENSG00000141759(TXNL4A) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell" FBgn0010324 Fs1 Female-specific 1 http://flybase.net/reports/FBgn0010324.html gene 16-Dec-15 2015_12 FBgn0043895 im(1)457 im(1)457 http://flybase.net/reports/FBgn0043895.html gene 0006955=immune response 16-Dec-15 2015_12 FBgn0000277 CecA2 Cecropin A2 http://flybase.net/reports/FBgn0000277.html protein_coding_gene "0042742=defense response to bacterium, 0019731=antibacterial humoral response, 0050832=defense response to fungus, 0006959=humoral immune response, 0050829=defense response to Gram-negative bacterium, 0050830=defense response to Gram-positive bacterium" 0005615=extracellular space "cecropinA2, cecropin A, cecropinA, cec, cecropin A2, Cecropin-A1/A2 precursor, crpA2, unnamed, Cec A2, Cecropin, Cecropin-A2, CG1367, Cecropin-A, cecA2, Cecropin A, CecA, Cec, cecropin, cecA" "IPR020400=Cecropin, diptera, IPR000875=Cecropin" CG1367 16-Dec-15 2015_12 " pupal stage , adult stage , larval stage " " adult fat body

, embryonic/larval hemocyte

" viable FBgn0040234 c12.2 c12.2 http://flybase.net/reports/FBgn0040234.html FBgn0030125 protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity" CG12149 "IPR011704=ATPase, dynein-related, AAA domain, IPR003593=AAA+ ATPase domain, IPR002035=von Willebrand factor, type A, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12149 16-Dec-15 2015_12 WBGene00008694(F11C1.5) ENSXETG00000018910() ENSMUSG00000058997 ENSG00000102763(KIAA0564) viable FBgn0266204 CR44899 http://flybase.net/reports/FBgn0266204.html non_protein_coding_gene CR44899 16-Dec-15 2015_12 FBgn0035883 CG13669 http://flybase.net/reports/FBgn0035883.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001235 hth homothorax http://flybase.net/reports/FBgn0001235.html "FBgn0010875, FBgn0011583, FBgn0015762, FBgn0016022, FBgn0025968" protein_coding_gene "0003677=DNA binding, 0035326=enhancer binding, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0035282=segmentation, 0045664=regulation of neuron differentiation, 0001752=compound eye photoreceptor fate commitment, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0010092=specification of organ identity, 0034504=protein localization to nucleus, 0001654=eye development, 0006357=regulation of transcription from RNA polymerase II promoter, 0060323=head morphogenesis, 0007380=specification of segmental identity, head, 0007480=imaginal disc-derived leg morphogenesis, 0007383=specification of segmental identity, antennal segment, 0048749=compound eye development, 0007479=leg disc proximal/distal pattern formation, 0009954=proximal/distal pattern formation, 0090098=positive regulation of decapentaplegic signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0042659=regulation of cell fate specification, 0007420=brain development, 0007525=somatic muscle development, 0007432=salivary gland boundary specification, 0007422=peripheral nervous system development, 0048735=haltere morphogenesis" "0005667=transcription factor complex, 0005634=nucleus, 0005829=cytosol, 0005737=cytoplasm" "unnamed, CG17117, Dm-HTH, l(3)05745, Hth, l(3)86Ca, 1422/04, P53, hth2, Meis1, dorsotonals, HTH, clone 2.13, Homothorax, dtl, hth1, Gene II, anon-EST:Liang-2.13, 1323/07" "IPR009057=Homeodomain-like, IPR001356=Homeobox domain, IPR008422=Homeobox KN domain" CG17117 16-Dec-15 2015_12 "ENSDARG00000042361(meis2.2),ENSDARG00000012078(meis1),ENSDARG00000002937(meis4.1a),ENSDARG00000002795(meis3)" WBGene00006796(unc-62) "ENSXETG00000012882(MEIS2),ENSXETG00000011473(MEIS1),ENSXETG00000002807(meis3)" "ENSMUSG00000027210(Meis2),ENSMUSG00000020160(Meis1),ENSMUSG00000041420(Meis3)" "ENSG00000134138(MEIS2),ENSG00000143995(MEIS1),ENSG00000105419(MEIS3),ENSG00000188013" " embryonic stage , larval stage | third instar , larval stage , embryonic stage | mid , embryonic stage | stage 7 , embryonic stage | stage >=15 , embryonic stage | stage >=11 , embryonic stage | stage >=6 , embryonic stage | stage >=13 , embryonic stage | cellular blastoderm , embryonic stage -- adult stage " " embryonic thorax

, embryonic nervous system

, antennal disc

, midgut constriction 1 | posterior to

, ventral thoracic disc

, endoderm | mid

, mesothoracic pleurum | presumptive

, Malpighian tubule

, organism | 10-90% egg length

, gastric caecum | primordium

, embryonic nervous system of thorax

, labral segment

, ectoderm

, peripodial epithelium

, embryonic central nervous system

, wing hinge | presumptive

, visceral mesoderm

, midgut constriction 3 | anterior to

, scutum | presumptive

, dorsal mesothoracic disc

, photoreceptor cell

, embryonic maxillary segment

, eye-antennal disc

, eye disc

, embryonic Malpighian tubule

, embryonic mandibular segment

, ptilinum | presumptive

, head capsule | presumptive

, ocellus | presumptive

" " larval stage | third instar , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage >=15 , embryonic stage | stage >=6 , larval stage | second instar , embryonic stage " " ventral thoracic disc

, wing hinge | presumptive

, embryonic central nervous system

, labral segment

, embryonic nervous system of thorax

, dorsal mesothoracic disc

, ectoderm

, embryonic maxillary segment

, ocellus | presumptive

, embryonic Malpighian tubule

, peripodial epithelium

, ptilinum | presumptive

, mesothoracic pleurum | presumptive

, eye disc

, antennal disc

, visceral mesoderm

, embryonic mandibular segment

, head capsule | presumptive

, scutum | presumptive

, photoreceptor cell

, embryonic thorax

" "lethal,recessive,homeotic,partially lethal - majority die,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,viable,visible,somatic clone,cell autonomous,size defective,dominant,male,planar polarity defective,cell non-autonomous,heat sensitive" "lch5 neuron,leg,ectopic,antenna,peripheral nervous system,sense organ & neuron,cephalopharyngeal skeleton,embryonic head,embryonic segment,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,abdominal lateral pentascolopidial chordotonal organ lch5,embryonic epidermis,somatic clone,metatarsus,tarsal segment 2,tarsal segment 3,tarsal segment 4,tarsal segment,pretarsus,mesothoracic tibial spur bristle,mesothoracic tibial apical bristle,prothoracic leg,mesothoracic leg,metathoracic leg,eye disc,embryonic/first instar larval cuticle,denticle belt,female genitalia,clasper,adult head,ventral,eye-antennal disc,antennal segment 2 & leg | somatic clone,antennal segment 3 & leg | somatic clone,eye & adult head | ventral,eye,photoreceptor cell,coxa,femur,tibia,motor neuron,glial cell,longitudinal connective,posterior commissure,embryonic ventral nervous system,cell autonomous,bract,wing margin,posterior,alula,wing sclerite,wing hinge,axillary cord,costal vein,wing vein L3,proximal,wing,double row,sensillum campaniformium of dorsal radius,wing margin bristle,scutellar bristle,wing disc,gena,rostral membrane,maxillary palpus,dorsal,embryonic thorax,abdominal segment 1,trochanter,dch3 neuron,embryonic/larval oenocyte precursor,medulla,transmedullary neuron Tm1,medullary intrinsic neuron Mi1,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,flight muscle,extracoxal depressor muscle,embryonic brain & axon,adult abdominal segment 4,male,adult abdominal segment 5,ommatidium,eye photoreceptor cell,dorsal margin photoreceptor,somatic clone - Minute background,heat sensitive,second segment of antenna,third segment of antenna,presumptive embryonic/larval peripheral nervous system,embryonic/larval lymph gland,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,embryonic thorax & denticle | ectopic,photoreceptor cell & eye-antennal disc | ventral,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,embryonic abdominal segment 1,prothoracic dorsal triscolopidial chordotonal organ dch3 & neuron,mesothoracic dorsal triscolopidial chordotonal organ dch3 & neuron,metathoracic dorsal triscolopidial chordotonal organ dch3 & neuron,distal,abdominal tergite 2,abdominal tergite 3,abdominal tergite & trichome | male | somatic clone,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,pseudotrachea,arista,sex comb,abdominal tergite 5 & trichome | malepnr-MD237,abdominal tergite 6 & trichome | malepnr-MD237,tergite,dorsal margin photoreceptor cell R8,photoreceptor cell R8,dorsal margin photoreceptor cell R7,ventral thoracic disc,morphogenetic furrow,leg sensillum,leg & trichome | somatic clone,unguis,alula & wing sensillumBx-MS1096,scutum,medial,cell non-autonomous,dorsocentral bristle,microchaeta & scutumMS248,antennal disc,head capsule,abdominal tergite 5,abdominal tergite 6,head,wing blade,haltere,retina,photoreceptor cell R7,abdominal segment 2,abdominal segment,Keilin's organ" FBgn0027635 ms(1)266 ms(1)266 http://flybase.net/reports/FBgn0027635.html gene 16-Dec-15 2015_12 male sterile spermatid & nucleus FBgn0030796 CG4829 http://flybase.net/reports/FBgn0030796.html protein_coding_gene "0003810=protein-glutamine gamma-glutamyltransferase activity, 0003840=gamma-glutamyltransferase activity" "0006749=glutathione metabolic process, 0048812=neuron projection morphogenesis" "IPR000101=Gamma-glutamyltranspeptidase, IPR029055=Nucleophile aminohydrolases, N-terminal" CG4829 16-Dec-15 2015_12 YLR299W(ECM38) WBGene00016906(C53D5.5) FBgn0086034 snoRNA:Me28S-G2743 http://flybase.net/reports/FBgn0086034.html snoRNA_gene "CR34663, Me28S-Gm2743" CR34663 16-Dec-15 2015_12 FBgn0028150 l(3)S044601 lethal (3) S044601 http://flybase.net/reports/FBgn0028150.html gene 0446/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0004083 Y-seqs Y-chromosome sequences http://flybase.net/reports/FBgn0004083.html FBgn0013400 repeat_region "anon-Y95-2, Y95-2" 16-Dec-15 2015_12 FBgn0037848 Tsp86D Tetraspanin 86D http://flybase.net/reports/FBgn0037848.html protein_coding_gene "0007399=nervous system development, 0045747=positive regulation of Notch signaling pathway, 0007298=border follicle cell migration" 0016021=integral component of membrane "CG4591, Dm.Tsp86D" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin, IPR018503=Tetraspanin, conserved site" CG4591 16-Dec-15 2015_12 "ENSDARG00000004497(tspan33),ENSDARG00000042189(LOC567512),ENSDARG00000042967(zgc:113223)" ENSMUSG00000001763(Tspan33) ENSG00000158457(TSPAN33) viable "sensory mother cell,somatic clone,supernumerary" FBgn0038838 TotB Turandot B http://flybase.net/reports/FBgn0038838.html FBgn0063107 protein_coding_gene "0009617=response to bacterium, 0034605=cellular response to heat, 0034644=cellular response to UV" "0005576=extracellular region, 0005615=extracellular space" "Tot B, Turandot, CG5609, turandot B, tot, BcDNA:LP06769" IPR010825=Stress-inducible humoral factor Turandot CG5609 16-Dec-15 2015_12 FBgn0264721 CR43989 http://flybase.net/reports/FBgn0264721.html non_protein_coding_gene CR43989 16-Dec-15 2015_12 FBgn0010076 Ni-K Nicked of Klein http://flybase.net/reports/FBgn0010076.html gene "Nicked, Ni" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0084807 1.1.3 1.1.3 http://flybase.net/reports/FBgn0084807.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0003121 pod podgy http://flybase.net/reports/FBgn0003121.html gene 16-Dec-15 2015_12 mitotic cell cycle defective FBgn0062537 anon-3929 anon-3929 http://flybase.net/reports/FBgn0062537.html gene 3929 16-Dec-15 2015_12 FBgn0052986 CG32986 http://flybase.net/reports/FBgn0052986.html FBgn0032071 protein_coding_gene CG15866 CG32986 16-Dec-15 2015_12 viable DRSC02509 K 0.532379035 -0.119388262 -0.003069778 0.695146429 2.088412578 0.367085636 FBgn0069150 mcl(3)Z3401 mcl(3)Z3401 http://flybase.net/reports/FBgn0069150.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0030899 Hesr HES-related http://flybase.net/reports/FBgn0030899.html protein_coding_gene "0046983=protein dimerization activity, 0003677=DNA binding" 0000122=negative regulation of transcription from RNA polymerase II promoter 0005634=nucleus "Her, bHLHc21, CG5927" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG5927 16-Dec-15 2015_12 viable FBgn0033770 wuc Wake-up-call http://flybase.net/reports/FBgn0033770.html FBgn0063299 protein_coding_gene 0005515=protein binding "0007140=male meiosis, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0070176=DRM complex, 0000790=nuclear chromatin" "CG12442, 147114_at, wake-up-call, Wake-up-call, BcDNA:AT27450, wuc" IPR018737=Protein LIN52 CG12442 16-Dec-15 2015_12 viable FBgn0036567 CG13074 http://flybase.net/reports/FBgn0036567.html protein_coding_gene "IPR007110=Immunoglobulin-like domain, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG13074 16-Dec-15 2015_12 viable FBgn0039582 Or98b Odorant receptor 98b http://flybase.net/reports/FBgn0039582.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0032590=dendrite membrane, 0016021=integral component of membrane" "Or98bP, DOR121, 98b, CG1867, 98C.1, or98b" "IPR004117=Olfactory receptor, Drosophila" CG1867 16-Dec-15 2015_12 viable FBgn0033817 GstE14 Glutathione S transferase E14 http://flybase.net/reports/FBgn0033817.html protein_coding_gene 0004364=glutathione transferase activity "0042632=cholesterol homeostasis, 0006749=glutathione metabolic process, 0045456=ecdysteroid biosynthetic process" 0005737=cytoplasm "GSTE14, noppera-bo, CG4688, gste14, nobo" "IPR004046=Glutathione S-transferase, C-terminal, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG4688 16-Dec-15 2015_12 YNL229C(URE2) viable FBgn0065083 snmRNA:765 small non-messenger RNA 765 http://flybase.net/reports/FBgn0065083.html FBgn0053789 non_protein_coding_gene "Dm-765, CR33789" CR33789 16-Dec-15 2015_12 FBgn0004225 l(3)84Fm lethal (3) 84Fm http://flybase.net/reports/FBgn0004225.html gene 16-Dec-15 2015_12 lethal FBgn0035255 RabX5 RabX5 http://flybase.net/reports/FBgn0035255.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction" "0045202=synapse, 0031982=vesicle" "CG7980, Q9W0A7, DmRabX5, rabX5" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG7980 16-Dec-15 2015_12 "ENSDARG00000014058(rab36),ENSDARG00000045628(rab34),ENSDARG00000010977(LOC100007678)" ENSXETG00000019257(rab34) "ENSMUSG00000002059(Rab34),ENSMUSG00000020175(Rab36)" "ENSG00000109113(RAB34),ENSG00000100228(RAB36)" "viable,fertile" FBgn0037705 mura murashka http://flybase.net/reports/FBgn0037705.html FBgn0037706 protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0007611=learning or memory, 2001020=regulation of response to DNA damage stimulus, 0007616=long-term memory, 0008355=olfactory learning, 0016567=protein ubiquitination, 0048149=behavioral response to ethanol" 0005634=nucleus "CG9382, Mura, CG9381, Murashka" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG9381 16-Dec-15 2015_12 "ENSMUSG00000056537(Rlim),ENSMUSG00000029634(Rnf6)" "ENSG00000131263(RLIM),ENSG00000127870(RNF6)" "viable,fertile,learning defective,memory defective,chemical resistant" DRSC23145 K 1.603695716 -0.197794796 FBgn0046880 Obp56b Odorant-binding protein 56b http://flybase.net/reports/FBgn0046880.html "FBgn0034469, FBgn0050129" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG15129, DmelObp56b, OBP56b, CG30129, 56b" IPR006170=Pheromone/general odorant binding protein CG30129 16-Dec-15 2015_12 viable FBgn0029079 icln icln http://flybase.net/reports/FBgn0029079.html FBgn0034250 protein_coding_gene 0005225=volume-sensitive anion channel activity "0006884=cell volume homeostasis, 0006821=chloride transport, 0000387=spliceosomal snRNP assembly" "0005886=plasma membrane, 0005829=cytosol, 0034709=methylosome, 0034715=pICln-Sm protein complex" "pICln, CG4924" IPR003521=ICln CG4924 16-Dec-15 2015_12 ENSDARG00000042615(icln) WBGene00002046(icl-1) ENSXETG00000010442(clns1a) ENSMUSG00000025439(Clns1a) ENSG00000074201(CLNS1A) viable FBgn0040041 CG17506 http://flybase.net/reports/FBgn0040041.html FBgn0058223 protein_coding_gene CG40223 16-Dec-15 2015_12 FBgn0264708 CR43977 http://flybase.net/reports/FBgn0264708.html non_protein_coding_gene CR43977 16-Dec-15 2015_12 FBgn0016900 l(3)72CDb lethal (3) 72CDb http://flybase.net/reports/FBgn0016900.html gene 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0038852 HHEX HHEX ortholog (H. sapiens) http://flybase.net/reports/FBgn0038852.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048813=dendrite morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0022008=neurogenesis, 0009744=response to sucrose, 0006006=glucose metabolic process" 0005634=nucleus "dHHEX, CG7056" "IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG7056 16-Dec-15 2015_12 "ENSDARG00000006982(msxd),ENSDARG00000056697(msxa),ENSDARG00000007641(msxe)" ENSXETG00000004060(NKX3-2) "lethal,chemical conditional,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,chemical sensitive,male limited,small body,female limited,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC16186 E 1.06117676 -0.050501548 3.497706995 -1.716624444 -1.272295111 -0.103251705 FBgn0039470 CG6296 http://flybase.net/reports/FBgn0039470.html protein_coding_gene "0008970=phosphatidylcholine 1-acylhydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process DmelL7 "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family, IPR002334=Vespid venom allergen phospholipase A1" CG6296 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) "viable,fertile" FBgn0054024 CR34024 http://flybase.net/reports/FBgn0054024.html FBgn0082650 non_protein_coding_gene "HDC15672, CG34024, BP1090, unnamed" CR34024 16-Dec-15 2015_12 FBgn0002285 soba suppressor of bulge and argos http://flybase.net/reports/FBgn0002285.html gene "l(3)73Aj, lethal(3)73Aj, l(3)std4" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0044518 ifm(2)RU486 indirect flight muscle (2) RU486 http://flybase.net/reports/FBgn0044518.html gene RU486 16-Dec-15 2015_12 "viable,visible,sterile,recessive,flight defective" "wing,indirect flight muscle" FBgn0267526 CR45866 http://flybase.net/reports/FBgn0267526.html non_protein_coding_gene CR45866 16-Dec-15 2015_12 FBgn0028590 l(3)L4222a lethal (3) L4222a http://flybase.net/reports/FBgn0028590.html gene l(3)L4222 16-Dec-15 2015_12 "lethal,recessive" FBgn0266164 CR44870 http://flybase.net/reports/FBgn0266164.html non_protein_coding_gene CR44870 16-Dec-15 2015_12 FBgn0022103 l(2)k07118b lethal (2) k07118b http://flybase.net/reports/FBgn0022103.html gene "(2)k07118b, l(2)k07118, l(2)k0711b" 16-Dec-15 2015_12 "lethal,recessive" FBgn0038492 Mur89F Mucin related 89F http://flybase.net/reports/FBgn0038492.html protein_coding_gene "0005201=extracellular matrix structural constituent, 0008061=chitin binding" 0006030=chitin metabolic process "0031012=extracellular matrix, 0005576=extracellular region" "CT13556, Mur89F, CG4090" IPR002557=Chitin binding domain CG4090 16-Dec-15 2015_12 viable DRSC15544 I 1.745683474 0.433702246 -0.635136681 -0.055825722 -0.394560534 -0.977250275 FBgn0267579 CR45919 http://flybase.net/reports/FBgn0267579.html non_protein_coding_gene pri-mir-124 CR45919 16-Dec-15 2015_12 FBgn0064153 p124 p124 http://flybase.net/reports/FBgn0064153.html gene P124 16-Dec-15 2015_12 FBgn0261814 CR42756 http://flybase.net/reports/FBgn0261814.html non_protein_coding_gene CR42756 16-Dec-15 2015_12 FBgn0003922 snRNA:U2:38ABa small nuclear RNA U2 at 38ABa http://flybase.net/reports/FBgn0003922.html FBgn0003919 snRNA_gene "0000398=mRNA splicing, via spliceosome" "0005686=U2 snRNP, 0015030=Cajal body" "snRNA-U2-141A, U2-141A, U2, snRNA2, dU2, snRNA:U2:39B, snRNA[[1]], U2:39AB, U2snRNA39B, Dm U2-141A, 38A U2, snRNA1, K6, CR32882, U2-38ABa, 141A, U2 snRNA, D.U2-3, U2:38ABa, U2snRNA, snRNA:U2, small nuclear RNA U2" CR32882 16-Dec-15 2015_12 FBgn0260346 GSd497 http://flybase.net/reports/FBgn0260346.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve" FBgn0040759 CG13177 http://flybase.net/reports/FBgn0040759.html protein_coding_gene CG13177 16-Dec-15 2015_12 FBgn0038359 CG5614 http://flybase.net/reports/FBgn0038359.html protein_coding_gene IPR006594=LIS1 homology motif CG5614 16-Dec-15 2015_12 "viable,fertile" FBgn0069240 fz::smo fz::smo http://flybase.net/reports/FBgn0069240.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing,costal cell,wing vein,ectopic,1st posterior cell" FBgn0014355 lup-2 loop unfolding protein-2 http://flybase.net/reports/FBgn0014355.html gene 0007288=sperm axoneme assembly "ms(3)HB267, male sterile (3) HB267" 16-Dec-15 2015_12 "male sterile,recessive" "Y chromosome loop,spermatid axoneme,axonemal dynein complex,axonemal microtubule | ectopic,axonemal microtubule | supernumerary" FBgn0038662 Mpc1 Mitochondrial pyruvate carrier http://flybase.net/reports/FBgn0038662.html protein_coding_gene 0050833=pyruvate transmembrane transporter activity "0006090=pyruvate metabolic process, 0006850=mitochondrial pyruvate transport" "0031305=integral component of mitochondrial inner membrane, 0005739=mitochondrion" "dMPC1, CG14290" IPR005336=Mitochondrial pyruvate carrier CG14290 16-Dec-15 2015_12 YGL080W(FMP37) WBGene00011119(R07E5.13) ENSXETG00000025990(bp44l) ENSG00000060762(BRP44L) "viable,fertile,neuroanatomy defective,lethal,nutrition conditional" neurite | pharate adult stage FBgn0044071 E(rst)K137 E(rst)K137 http://flybase.net/reports/FBgn0044071.html gene 0001745=compound eye morphogenesis K137 16-Dec-15 2015_12 FBgn0259453 EP-J63.2 http://flybase.net/reports/FBgn0259453.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0265859 CR44648 http://flybase.net/reports/FBgn0265859.html non_protein_coding_gene CR44648 16-Dec-15 2015_12 FBgn0034362 CG5323 http://flybase.net/reports/FBgn0034362.html protein_coding_gene "IPR008560=Protein of unknown function DUF842, eukaryotic" CG5323 16-Dec-15 2015_12 ENSDARG00000040148(fam136a) WBGene00014022(ZK637.2) ENSXETG00000008511(FAM136A) ENSMUSG00000057497(Fam136a) ENSG00000035141(FAM136A) viable FBgn0069426 JJF015 JJF015 http://flybase.net/reports/FBgn0069426.html gene 16-Dec-15 2015_12 stress response defective FBgn0025763 l(3)89Em lethal (3) 89Em http://flybase.net/reports/FBgn0025763.html gene l(3)M96 16-Dec-15 2015_12 "lethal,recessive" FBgn0035797 CG14837 http://flybase.net/reports/FBgn0035797.html protein_coding_gene CG14837 16-Dec-15 2015_12 viable FBgn0016080 xmas-1 xmas-1 http://flybase.net/reports/FBgn0016080.html "FBgn0030822, FBgn0052561" protein_coding_gene "CG32561, CG8919, ms3, transcript g, l(1)15Ea, ms(1)3, m(1)3, xmas" CG32561 16-Dec-15 2015_12 "meiotic cell cycle defective,male sterile,viable" FBgn0082988 snoRNA:ë¬28S-2442b snoRNA:ë¬28S-2442b http://flybase.net/reports/FBgn0082988.html snoRNA_gene "psi28s-2442b, CR34612, chr3R:1424176..1424319" CR34612 16-Dec-15 2015_12 FBgn0003697 thic thickened aristae http://flybase.net/reports/FBgn0003697.html gene 0007629=flight behavior 16-Dec-15 2015_12 "lethal,heat sensitive,eye color defective" "arista,sex comb,eye" FBgn0032636 CG5043 http://flybase.net/reports/FBgn0032636.html protein_coding_gene CG5043 16-Dec-15 2015_12 FBgn0033207 CG12826 http://flybase.net/reports/FBgn0033207.html protein_coding_gene CG12826 16-Dec-15 2015_12 FBgn0069075 ttf tintenfisch http://flybase.net/reports/FBgn0069075.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic thorax,germline clone,maternal effect,embryonic head,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0268063 ltl larval translucida http://flybase.net/reports/FBgn0268063.html "FBgn0052372, FBgn0019866, FBgn0035794, FBgn0040836, FBgn0002519" protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 0007474=imaginal disc-derived wing vein specification" 0005615=extracellular space "CG32372, lethal (3) translucida, lethal translucida, CG14836, lincRNA.S4366, F, CG7545, anon-EST:CL1a11, l(3)tr, CT15760" "IPR001611=Leucine-rich repeat, IPR026906=Leucine rich repeat 5, IPR003591=Leucine-rich repeat, typical subtype" CG32372 16-Dec-15 2015_12 ENSMUSG00000050675(Gp1ba) FBgn0026249 ego early germ cell overproliferation http://flybase.net/reports/FBgn0026249.html gene "0048133=male germ-line stem cell asymmetric division, 0007283=spermatogenesis, 0008356=asymmetric cell division" 16-Dec-15 2015_12 FBgn0035211 CG2211 http://flybase.net/reports/FBgn0035211.html FBgn0062156 protein_coding_gene anon-WO0118547.230 CG2211 16-Dec-15 2015_12 viable FBgn0060369 l(3)S138102 lethal (3) S138102 http://flybase.net/reports/FBgn0060369.html gene 1381/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0083981 RunxA http://flybase.net/reports/FBgn0083981.html "FBan0001379, FBan0015453, FBgn0031123, FBgn0031124" protein_coding_gene "0005524=ATP binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis" 0005634=nucleus "CG15453, CG34145, CG1379" "IPR000040=Acute myeloid leukemia 1 protein (AML1)/Runt, IPR012346=p53/RUNT-type transcription factor, DNA-binding domain, IPR008967=p53-like transcription factor, DNA-binding, IPR013524=Runt domain" CG34145 16-Dec-15 2015_12 "ENSDARG00000040261(runx2a),ENSDARG00000059233(runx2b),ENSDARG00000052826(runx3)" WBGene00004393(rnt-1) "ENSXETG00000014140(RUNX1),ENSXETG00000001397()" "lethal,neuroanatomy defective" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0025141 ms(3)A6 ms(3)A6 http://flybase.net/reports/FBgn0025141.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0267738 CR46069 http://flybase.net/reports/FBgn0267738.html non_protein_coding_gene Mgn94068 CR46069 16-Dec-15 2015_12 FBgn0032175 CG13131 http://flybase.net/reports/FBgn0032175.html protein_coding_gene CG13131 16-Dec-15 2015_12 "viable,fertile" FBgn0259478 EP-336 http://flybase.net/reports/FBgn0259478.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta,ectopic" FBgn0265197 CG44257 http://flybase.net/reports/FBgn0265197.html protein_coding_gene CG44257 16-Dec-15 2015_12 FBgn0023085 fcG fcG http://flybase.net/reports/FBgn0023085.html gene 16-Dec-15 2015_12 FBgn0083000 snoRNA:ë¬28S-1192b snoRNA:ë¬28S-1192b http://flybase.net/reports/FBgn0083000.html snoRNA_gene "Psi28S-1192b, CR34596, psi28S-1192b, chrX:16978184..16978371" CR34596 16-Dec-15 2015_12 FBgn0001589 l(1)carot6 lethal (1) carot6 http://flybase.net/reports/FBgn0001589.html gene 16-Dec-15 2015_12 lethal FBgn0265610 CG44428 http://flybase.net/reports/FBgn0265610.html protein_coding_gene CG44428 16-Dec-15 2015_12 FBgn0032787 CG10195 http://flybase.net/reports/FBgn0032787.html protein_coding_gene 0016787=hydrolase activity "IPR015797=NUDIX hydrolase domain-like, IPR000086=NUDIX hydrolase domain" CG10195 16-Dec-15 2015_12 WBGene00003584(ndx-7) "viable,fertile" DRSC02026 I 0.919479269 2.004256654 -0.465537298 0.716693186 -0.803214372 -0.06901763 FBgn0000377 crn crooked neck http://flybase.net/reports/FBgn0000377.html "FBgn0004044, FBgn0042162" protein_coding_gene 0044822=poly(A) RNA binding "0007422=peripheral nervous system development, 0007417=central nervous system development, 0022008=neurogenesis, 0007443=Malpighian tubule morphogenesis, 0007405=neuroblast proliferation, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0048663=neuron fate commitment, 0051298=centrosome duplication, 0008366=axon ensheathment, 0008347=glial cell migration, 0000398=mRNA splicing, via spliceosome, 0007438=oenocyte development" "0005737=cytoplasm, 0016607=nuclear speck, 0005813=centrosome, 0072686=mitotic spindle, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0005681=spliceosomal complex" "Crn, l(1)CRN, l(1)crn, yok, N10, l(1)2, 62D9.a, N5, RC63, CG3193, EG:30B8.1, l(1)2Fa, l30, CG18842, yolky, l(1)N7" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR003107=HAT (Half-A-TPR) repeat" CG3193 16-Dec-15 2015_12 ENSDARG00000007901 YLR117C(CLF1) WBGene00019762(M03F8.3) ENSXETG00000009698(CRNKL1) ENSMUSG00000001767(Crnkl1) ENSG00000101343(CRNKL1) " embryonic stage , adult stage | female "

ubiquitous "some die during embryonic stage,recessive,lethal - all die before end of embryonic stage,wild-type,lethal,germline clone,dominant,neuroanatomy defective,cell lethal,viable,lethal - all die before end of pupal stage,some die during pupal stage" "glial cell,embryo,Malpighian tubule,embryonic Malpighian tubule,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval glial cell,peripheral glial cell,embryonic/larval oenocyte precursor" DRSC18184 EK -0.735668429 0.757430033 2.329051917 0.656615062 -1.877734444 0.163732937 FBgn0026713 l(1)G0007 lethal (1) G0007 http://flybase.net/reports/FBgn0026713.html "FBgn0026709, FBgn0027309, FBgn0028281, FBgn0029047, FBgn0030546, FBgn0030550, FBgn0040139, FBgn0040178, FBgn0040194, FBgn0044447, FBgn0044450, FBgn0052604" protein_coding_gene "0003676=nucleic acid binding, 0008026=ATP-dependent helicase activity, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior" 0005681=spliceosomal complex "unnamed, CG32604, l(1)G0308, l(1)G0416, Prp16, l(1)G0176, CG1375, prp16, CG1405, l(1)G0103, lethal (1) G0007, l(1)G0028, cg1405, l(1)G0491, EP764, l(1)G0476, EP784" "IPR011709=Domain of unknown function DUF1605, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR007502=Helicase-associated domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR011545=DEAD/DEAH box helicase domain" CG32604 16-Dec-15 2015_12 ENSDARG00000053946(dhx38) YKR086W(PRP16) WBGene00003389(mog-1) ENSMUSG00000037993(Dhx38) ENSG00000140829(DHX38) "behavior defective,recessive,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,male limited,viable,fertile,lethal,neuroanatomy defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,some die during pupal stage" "macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval brain,mesothoracic tergum,trichogen cell" FBgn0005154 l(2)G97 lethal (2) G97 http://flybase.net/reports/FBgn0005154.html gene 16-Dec-15 2015_12 lethal FBgn0084016 CG41453 http://flybase.net/reports/FBgn0084016.html FBan0041453 protein_coding_gene 16-Dec-15 2015_12 FBgn0030946 CG6659 http://flybase.net/reports/FBgn0030946.html protein_coding_gene 0000030=mannosyltransferase activity 0016021=integral component of membrane "IPR030038=C-mannosyltransferase Dpy-19, IPR018732=Dpy-19/Dpy-19-like" CG6659 16-Dec-15 2015_12 ENSDARG00000069995(LOC100331354) WBGene00001078(dpy-19) ENSXETG00000001414() ENSMUSG00000043067(Dpy19l1) "ENSG00000173852(DPY19L1),ENSG00000177990(DPY19L2)" "viable,fertile" FBgn0033132 Tsp42Ej Tetraspanin 42Ej http://flybase.net/reports/FBgn0033132.html protein_coding_gene "0071486=cellular response to high light intensity, 0006897=endocytosis" "0005764=lysosome, 0016021=integral component of membrane" "sun, tetraspanin 42E, sunglass, CG12143, Sun, Dm.Tsp42Ej, Sunglasses, tsp42ej, sunglasses" "IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG12143 16-Dec-15 2015_12 "viable,fertile,visible" "retina,trichogen cell" FBgn0264524 ff18 http://flybase.net/reports/FBgn0264524.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" spermatid FBgn0065655 l(2)SH0723 lethal (2) SH0723 http://flybase.net/reports/FBgn0065655.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016123 Alp4 Alkaline phosphatase 4 http://flybase.net/reports/FBgn0016123.html FBgn0010913 protein_coding_gene 0004035=alkaline phosphatase activity "0007399=nervous system development, 0032504=multicellular organism reproduction, 0016311=dephosphorylation, 0042045=epithelial fluid transport" "0005576=extracellular region, 0009986=cell surface, 0005615=extracellular space" "Alkaline phosphatase-4, Aph-4, CG1462, l(3)07028, Alkaline phosphatase, unnamed, aph-4, pMY51, alkaline phosphatase" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase, IPR018299=Alkaline phosphatase, active site, IPR017850=Alkaline-phosphatase-like, core domain" CG1462 16-Dec-15 2015_12 YDR481C(PHO8) " adult stage , larval stage && adult stage " " Malpighian tubule

, ellipsoid body

" "viable,partially lethal - majority die,recessive,lethal" adult Malpighian tubule FBgn0267017 CR45461 http://flybase.net/reports/FBgn0267017.html non_protein_coding_gene CR45461 16-Dec-15 2015_12 FBgn0040109 l(3)tk21 lethal (3) tk21 http://flybase.net/reports/FBgn0040109.html gene tk21 16-Dec-15 2015_12 "lethal,recessive" FBgn0060897 l(3)S044306 lethal (3) S044306 http://flybase.net/reports/FBgn0060897.html gene 0443/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0261918 EndoA::Hsap\ARFIP2 http://flybase.net/reports/FBgn0261918.html engineered_fusion_gene endoA::Hsap\ARFIP2 16-Dec-15 2015_12 FBgn0004483 l(1)air10 lethal aberrant immune response 10 http://flybase.net/reports/FBgn0004483.html gene air10 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0052856 CG32856 http://flybase.net/reports/FBgn0052856.html FBgn0064930 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006366=transcription from RNA polymerase II promoter, 0006384=transcription initiation from RNA polymerase III promoter" 0005634=nucleus BcDNA:GM32296 IPR029138=snRNA-activating protein complex subunit 5 CG32856 16-Dec-15 2015_12 FBgn0040038 klhl10 http://flybase.net/reports/FBgn0040038.html "FBgn0044727, FBan0012423" protein_coding_gene "0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0016567=protein ubiquitination, 0007291=sperm individualization" 0031463=Cul3-RING ubiquitin ligase complex "CG12423, anon-WO0140519.152, klhl10" "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR015916=Galactose oxidase, beta-propeller, IPR011705=BTB/Kelch-associated, IPR030608=Kelch-like protein 10, IPR006652=Kelch repeat type 1" CG12423 16-Dec-15 2015_12 "ENSDARG00000028548,ENSDARG00000005814(LOC100333629)" "WBGene00002186(kel-10),WBGene00018563(F47D12.7)" ENSXETG00000003818(KLHL10) ENSMUSG00000001558(Klhl10) ENSG00000161594(KLHL10) "viable,visible,male sterile,recessive" "eye,ommatidium,spermatid" DRSC20925 I 1.728214047 0.063898099 -0.681175424 0.391517731 FBgn0011194 l(1)302-3 lethal (1) 302-3 http://flybase.net/reports/FBgn0011194.html FBgn0010202 gene 302-3 16-Dec-15 2015_12 "lethal,recessive" FBgn0263886 l(3)C26 http://flybase.net/reports/FBgn0263886.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0051301 CG31301 http://flybase.net/reports/FBgn0051301.html FBgn0038322 protein_coding_gene 0003676=nucleic acid binding CG12258 "IPR001374=R3H domain, IPR021859=XRN-Two Binding Domain, XTBD, IPR000467=G-patch domain" CG31301 16-Dec-15 2015_12 "viable,fertile" FBgn0067402 Rst(2)DDT-EMS2 Resistant to DDT on II EMS2 http://flybase.net/reports/FBgn0067402.html gene Rst(2)DDT 16-Dec-15 2015_12 chemical resistant FBgn0037894 Ranbp9 Ranbp9 http://flybase.net/reports/FBgn0037894.html protein_coding_gene 0008536=Ran GTPase binding 0006886=intracellular protein transport CG5252 "IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical" CG5252 16-Dec-15 2015_12 ENSDARG00000016753(ipo9) YGL241W(KAP114) ENSXETG00000007974(IPO9) ENSMUSG00000041879(Ipo9) ENSG00000198700(IPO9) viable FBgn0266259 CG44954 http://flybase.net/reports/FBgn0266259.html protein_coding_gene lincRNA.900 CG44954 16-Dec-15 2015_12 FBgn0033806 FLASH FLASH ortholog http://flybase.net/reports/FBgn0033806.html protein_coding_gene 0005515=protein binding 0006398=histone mRNA 3'-end processing "0071204=histone pre-mRNA 3'end processing complex, 0035363=histone locus body" "CG4616, dFLASH" CG4616 16-Dec-15 2015_12 "viable,female sterile,female semi-sterile" FBgn0036109 Cpr67Fa2 Cuticular protein 67Fa2 http://flybase.net/reports/FBgn0036109.html FBgn0063135 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG18349, BcDNA:LP01241, DmelCpr67Fa2" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG18349 16-Dec-15 2015_12 FBgn0040753 CG13341 http://flybase.net/reports/FBgn0040753.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004993 Cli Clipped wings http://flybase.net/reports/FBgn0004993.html gene 16-Dec-15 2015_12 "viable,visible,dominant" wing FBgn0060543 l(3)S099102 lethal (3) S099102 http://flybase.net/reports/FBgn0060543.html gene 0991/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266186 Vamp7 Vesicle-associated membrane protein 7 http://flybase.net/reports/FBgn0266186.html "FBgn0067041, FBgn0033452" protein_coding_gene "0005484=SNAP receptor activity, 0000149=SNARE binding, 0019905=syntaxin binding" "0006906=vesicle fusion, 0006886=intracellular protein transport, 0097352=autophagic vacuole maturation, 0008333=endosome to lysosome transport, 0000046=autophagic vacuole fusion" "0031201=SNARE complex, 0005886=plasma membrane, 0016021=integral component of membrane, 0031902=late endosome membrane" "Vamp7, CG1599, TI-VAMP, VAMP7" "IPR010908=Longin domain, IPR011012=Longin-like domain, IPR001388=Synaptobrevin" CG1599 16-Dec-15 2015_12 ENSDARG00000030775(sybl1) ENSXETG00000018389(VAMP7) ENSMUSG00000051412 ENSG00000124333(VAMP7) FBgn0047114 CG31142 http://flybase.net/reports/FBgn0047114.html FBgn0051142 protein_coding_gene BcDNA:RE39515 "IPR019191=Essential protein Yae1, N-terminal" CG31142 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0023218 E(lz)205 E(lz)205 http://flybase.net/reports/FBgn0023218.html gene 16-Dec-15 2015_12 wild-type FBgn0267152 CR45592 http://flybase.net/reports/FBgn0267152.html non_protein_coding_gene CR45592 16-Dec-15 2015_12 FBgn0011694 EbpII Ejaculatory bulb protein II http://flybase.net/reports/FBgn0011694.html protein_coding_gene "0032504=multicellular organism reproduction, 0045434=negative regulation of female receptivity, post-mating, 0045297=post-mating behavior" 0005615=extracellular space "PEBmeII, CG2665, PEBII, PEB, Protein ejaculatory bulb II, PebII, PEB2" CG2665 16-Dec-15 2015_12 viable FBgn0069070 194-26 194-26 http://flybase.net/reports/FBgn0069070.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" FBgn0266395 CR45035 http://flybase.net/reports/FBgn0266395.html non_protein_coding_gene CR45035 16-Dec-15 2015_12 FBgn0000072 Ama-1 ë± Amanitin-resistant 1 http://flybase.net/reports/FBgn0000072.html gene 16-Dec-15 2015_12 FBgn0022241 l(2)k02206 lethal (2) k02206 http://flybase.net/reports/FBgn0022241.html gene l(2)K02206 16-Dec-15 2015_12 "lethal,recessive" FBgn0266316 CR44981 http://flybase.net/reports/FBgn0266316.html non_protein_coding_gene CR44981 16-Dec-15 2015_12 FBgn0064245 E(tc) Enhancer of terminal gene conversion http://flybase.net/reports/FBgn0064245.html gene 0000723=telomere maintenance 16-Dec-15 2015_12 FBgn0260263 GSd491 http://flybase.net/reports/FBgn0260263.html gene 16-Dec-15 2015_12 lethal FBgn0261290 CheA84a Chemosensory protein A 84a http://flybase.net/reports/FBgn0261290.html "FBgn0067314, FBgn0053779" protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CheA84a, CG33779" IPR010512=Protein of unknown function DUF1091 CG33779 16-Dec-15 2015_12 FBgn0264488 CG43896 http://flybase.net/reports/FBgn0264488.html "FBgn0036234, FBgn0036233" protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region "CG6947, CG17824" IPR002557=Chitin binding domain CG43896 16-Dec-15 2015_12 WBGene00010351(cbd-1) FBgn0052079 CG32079 http://flybase.net/reports/FBgn0052079.html FBgn0036114 protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport CG11806 "IPR013057=Amino acid transporter, transmembrane domain" CG32079 16-Dec-15 2015_12 "YNL101W(AVT4),YKL146W(AVT3)" viable FBgn0065245 l(2)SH2139 lethal (2) SH2139 http://flybase.net/reports/FBgn0065245.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083978 CG17672 http://flybase.net/reports/FBgn0083978.html "FBan0011271, FBgn0011809, FBgn0014027, FBgn0036339, FBgn0064825" protein_coding_gene "BcDNA:RH29995, CG11271" IPR029034=Cystine-knot cytokine CG17672 16-Dec-15 2015_12 DRSC09230 IEK -1.596333134 -4.667639633 -3.107365662 -7.463030115 -2.166717698 -0.27010061 FBgn0261796 Ote::Hsap\EMD http://flybase.net/reports/FBgn0261796.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0039376 CG14354 http://flybase.net/reports/FBgn0039376.html protein_coding_gene IPR007999=Protein of unknown function DUF745 CG14354 16-Dec-15 2015_12 FBgn0265681 CR44488 http://flybase.net/reports/FBgn0265681.html non_protein_coding_gene CR44488 16-Dec-15 2015_12 FBgn0052574 Twdlë± Tweedleë± http://flybase.net/reports/FBgn0052574.html FBgn0030785 protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development, 0022008=neurogenesis" 0005578=proteinaceous extracellular matrix "CG4724, CG32574" IPR004145=Domain of unknown function DUF243 CG32574 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0267122 CR45562 http://flybase.net/reports/FBgn0267122.html non_protein_coding_gene CR45562 16-Dec-15 2015_12 FBgn0086206 E(ls)1 http://flybase.net/reports/FBgn0086206.html gene 16-Dec-15 2015_12 FBgn0033987 ckn caskin http://flybase.net/reports/FBgn0033987.html FBgn0047267 protein_coding_gene "0035591=signaling adaptor activity, 0019903=protein phosphatase binding" "0007185=transmembrane receptor protein tyrosine phosphatase signaling pathway, 0007411=axon guidance, 0007409=axonogenesis" "0005925=focal adhesion, 0030424=axon, 0005737=cytoplasm" "BcDNA:GM06913, CG12424" "IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain" CG12424 16-Dec-15 2015_12 "ENSDARG00000068462(LOC100147893),ENSDARG00000046107(caskin1),ENSDARG00000019669" WBGene00016725(C46H3.2) "ENSG00000177303(CASKIN2),ENSG00000167971(CASKIN1)" "learning defective,lethal,neuroanatomy defective,viable" "axon | embryonic stageelav.PLu,fascicle | embryonic stage,intersegmental nerve branch ISNb of A1-7 | embryonic stage,axon | embryonic stageexex-Gal4,intersegmental nerve,intersegmental nerve branch ISNb of A1-7" FBgn0044811 TotF Turandot F http://flybase.net/reports/FBgn0044811.html "FBgn0032829, FBgn0051691" protein_coding_gene "0034605=cellular response to heat, 0009617=response to bacterium, 0034644=cellular response to UV" "0005615=extracellular space, 0005576=extracellular region" "tot, Tot F, CG13963, CG31691" IPR010825=Stress-inducible humoral factor Turandot CG31691 16-Dec-15 2015_12 viable FBgn0069201 l(2)DJ684 lethal (2) DJ684 http://flybase.net/reports/FBgn0069201.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037249 eIF3-S10 eIF3-S10 http://flybase.net/reports/FBgn0037249.html "FBan0009805, FBgn0062137" protein_coding_gene 0003743=translation initiation factor activity "0006446=regulation of translational initiation, 0007052=mitotic spindle organization, 0006413=translational initiation, 0000022=mitotic spindle elongation" "0005829=cytosol, 0005852=eukaryotic translation initiation factor 3 complex" "anon-WO0118547.261, MMAP140, eIF3-s10, EIF3-S10, CG9805, eIF3a" "IPR000717=Proteasome component (PCI) domain, IPR027512=Eukaryotic translation initiation factor 3 subunit A, IPR011991=Winged helix-turn-helix DNA-binding domain" CG9805 16-Dec-15 2015_12 ENSDARG00000039702(eif3s10) YBR079C(RPG1) WBGene00001209(egl-45) ENSXETG00000010241(EIF3A) ENSMUSG00000024991(Eif3a) ENSG00000107581(EIF3A) "lethal,female fertile,female sterile" DRSC28481 IEK -2.942826222 -1.26835195 -2.418198991 -4.103788702 0.591454306 1.608240127 FBgn0024983 CG4293 http://flybase.net/reports/FBgn0024983.html protein_coding_gene 0006888=ER to Golgi vesicle-mediated transport 0030134=ER to Golgi transport vesicle "154711_at, EG:65F1.1" "IPR012936=Endoplasmic reticulum vesicle transporter, C-terminal" CG4293 16-Dec-15 2015_12 "ENSDARG00000051936(ergic2),ENSDARG00000020224" YML067C(ERV41) ENSXETG00000000324(ptx1) ENSMUSG00000030304(Ergic2) ENSG00000087502(ERGIC2) "viable,fertile" FBgn0063649 CG6006 http://flybase.net/reports/FBgn0063649.html FBgn0038403 protein_coding_gene 0015226=carnitine transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane BcDNA:SD04753 "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG6006 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "viable,fertile" FBgn0061077 l(3)S015012 lethal (3) S015012 http://flybase.net/reports/FBgn0061077.html gene 0150/12 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0023445 dsx-c98D doublesex cognate 98D http://flybase.net/reports/FBgn0023445.html gene dsx-c98 16-Dec-15 2015_12 FBgn0005457 l(1)v454 lethal (1) v454 http://flybase.net/reports/FBgn0005457.html gene l(1)454 16-Dec-15 2015_12 FBgn0262204 mir-2279 mir-2279 stem loop http://flybase.net/reports/FBgn0262204.html miRNA_gene "miR-2279, dme-mir-2279, CR42911" CR42911 16-Dec-15 2015_12 viable FBgn0260252 GSd332 http://flybase.net/reports/FBgn0260252.html gene 16-Dec-15 2015_12 lethal FBgn0069067 30-1 30-1 http://flybase.net/reports/FBgn0069067.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038337 CG6125 http://flybase.net/reports/FBgn0038337.html protein_coding_gene "0015381=high-affinity sulfate transmembrane transporter activity, 0005215=transporter activity" "0055085=transmembrane transport, 0008272=sulfate transport" 0016021=integral component of membrane "IPR011547=SLC26A/SulP transporter domain, IPR002645=STAS domain, IPR001902=SLC26A/SulP transporter" CG6125 16-Dec-15 2015_12 "YLR092W(SUL2),YBR294W(SUL1)" viable FBgn0036106 CG6409 http://flybase.net/reports/FBgn0036106.html protein_coding_gene 0006506=GPI anchor biosynthetic process 0005783=endoplasmic reticulum CG6409 16-Dec-15 2015_12 viable FBgn0002018 l(2)37Ab lethal (2) 37Ab http://flybase.net/reports/FBgn0002018.html gene "Ab, l(2)E129" 16-Dec-15 2015_12 lethal FBgn0065779 l(2)SH0446 lethal (2) SH0446 http://flybase.net/reports/FBgn0065779.html gene l(2)SH2 0446 16-Dec-15 2015_12 "lethal,recessive" FBgn0259289 C174 http://flybase.net/reports/FBgn0259289.html gene 16-Dec-15 2015_12 visible "wing hair,wing vein" FBgn0260753 Pdfr Pigment-dispersing factor receptor http://flybase.net/reports/FBgn0260753.html "FBgn0040378, FBgn0029622, FBgn0046581, FBgn0046582, FBgn0082641" protein_coding_gene "0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity, 0004948=calcitonin receptor activity" "0045475=locomotor rhythm, 0060086=circadian temperature homeostasis, 0048512=circadian behavior, 0007623=circadian rhythm, 0007186=G-protein coupled receptor signaling pathway, 0042745=circadian sleep/wake cycle, 0042749=regulation of circadian sleep/wake cycle, 0042332=gravitaxis, 0007218=neuropeptide signaling pathway, 0055070=copper ion homeostasis, 0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway" "0043005=neuron projection, 0005887=integral component of plasma membrane, 0043025=neuronal cell body, 0016021=integral component of membrane" "Han, Pdf recep- tor, PDFR, groom-of-pdf, unnamed, anon-WO0170980.158, anon-WO0170980.157, PDF Receptor, BACR25B3.3, Pdfr, Pigment dispersing factor receptor, PDF-R1, CG13758, groom-of-PDF, Pdf-R1, DmeCG13758, PdfR, Pigment dispersing factor receptor 1, PDF receptor, PDF-receptor, pigment-dispersing factor receptor, han, gop, pdfr, EG:BACR25B3.3, Pdf receptor, Pigment-Dispersing Factor Receptor" "IPR017981=GPCR, family 2-like, IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR000832=GPCR, family 2, secretin-like, IPR017983=GPCR, family 2, secretin-like, conserved site" CG13758 16-Dec-15 2015_12 WBGene00015735(pdfr-1) FBgn0260401 MED9 Mediator complex subunit 9 http://flybase.net/reports/FBgn0260401.html "FBgn0034311, FBgn0050112, FBgn0050113, FBgn0063166, FBgn0064814, FBan0005134, FBgn0260391" protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0006357=regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0007406=negative regulation of neuroblast proliferation" 0016592=mediator complex "CG30112, BcDNA:RH42446, CG42517, CG5134, med9, BcDNA:LD07740, CG30113" "IPR011425=Mediator complex, subunit Med9" CG42517 16-Dec-15 2015_12 DRSC06917 K -1.291763872 1.456262888 -1.139790733 0.540936479 1.892200088 2.329893108 FBgn0035907 GstO1 Glutathione S transferase O1 http://flybase.net/reports/FBgn0035907.html protein_coding_gene "0004734=pyrimidodiazepine synthase activity, 0016782=transferase activity, transferring sulfur-containing groups, 0045174=glutathione dehydrogenase (ascorbate) activity, 0004364=glutathione transferase activity" 0006749=glutathione metabolic process 0005737=cytoplasm "CG6662, GSTO1" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR005442=Glutathione S-transferase, omega-class, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold" CG6662 16-Dec-15 2015_12 "ENSDARG00000022183(zgc:92254),ENSDARG00000033285(zgc:101897)" "WBGene00019636(gsto-3),WBGene00001792(gst-44),WBGene00016204(gsto-1)" "ENSXETG00000026602(TEgg023j21.1),ENSXETG00000026601(BC087558.1),ENSXETG00000016907()" "ENSMUSG00000025068(Gsto1),ENSMUSG00000025069(Gsto2)" "ENSG00000148834(GSTO1),ENSG00000065621(GSTO2)" viable DRSC10688 I 0.784712297 1.521778987 -0.353827186 0.135821259 0.443717298 0.145578918 FBgn0011679 NssBF Nuclear single stranded DNA-binding factor http://flybase.net/reports/FBgn0011679.html gene 0003697=single-stranded DNA binding 16-Dec-15 2015_12 FBgn0262972 CR43283 http://flybase.net/reports/FBgn0262972.html non_protein_coding_gene "Dm_3R:37919, lincRNA.752" CR43283 16-Dec-15 2015_12 FBgn0030239 CG17333 http://flybase.net/reports/FBgn0030239.html protein_coding_gene 0017057=6-phosphogluconolactonase activity "0006098=pentose-phosphate shunt, 0005975=carbohydrate metabolic process" Pgls "IPR006148=Glucosamine/galactosamine-6-phosphate isomerase, IPR005900=6-phosphogluconolactonase, DevB-type" CG17333 16-Dec-15 2015_12 "ENSDARG00000021233(pgls),ENSDARG00000067615" "YHR163W(SOL3),YGR248W(SOL4)" WBGene00013301(Y57G11C.3) ENSXETG00000020569(Q5HZC7_XENTR) ENSMUSG00000031807(Pgls) ENSG00000130313(PGLS) "viable,fertile" FBgn0051210 CG31210 http://flybase.net/reports/FBgn0051210.html protein_coding_gene CG4836 16-Dec-15 2015_12 FBgn0040740 CG14494 http://flybase.net/reports/FBgn0040740.html protein_coding_gene 16-Dec-15 2015_12 FBgn0069203 l(2)46Fa lethal (2) 46Fa http://flybase.net/reports/FBgn0069203.html gene Complementation group Y 16-Dec-15 2015_12 "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0028392 anon-50ABb anon-50ABb http://flybase.net/reports/FBgn0028392.html gene B 16-Dec-15 2015_12 FBgn0065943 l(2)SH0109 lethal (2) SH0109 http://flybase.net/reports/FBgn0065943.html gene l(2)SH2 0109 16-Dec-15 2015_12 "lethal,recessive" FBgn0035546 CG11345 http://flybase.net/reports/FBgn0035546.html protein_coding_gene CG11345 16-Dec-15 2015_12 FBgn0261841 pre-mod(mdg4)-AD http://flybase.net/reports/FBgn0261841.html protein_coding_gene CG42773 "IPR007588=Zinc finger, FLYWCH-type" CG42773 16-Dec-15 2015_12 FBgn0033497 CG12912 http://flybase.net/reports/FBgn0033497.html protein_coding_gene CG12912 16-Dec-15 2015_12 FBgn0031643 CG3008 http://flybase.net/reports/FBgn0031643.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "0005737=cytoplasm, 0005634=nucleus" "IPR011009=Protein kinase-like domain, IPR017406=Serine/threonine-protein kinase Rio3, IPR000687=RIO kinase" CG3008 16-Dec-15 2015_12 ENSDARG00000042751(riok3) WBGene00014012(riok-3) ENSXETG00000027370(riok3) ENSMUSG00000024404(Riok3) ENSG00000101782(RIOK3) viable DRSC00560 I 1.853955276 0.044058262 0.205067846 0.01739177 0.082206766 0.184365511 FBgn0031613 HP6 Heterochromatin protein 6 http://flybase.net/reports/FBgn0031613.html protein_coding_gene "0003682=chromatin binding, 0003677=DNA binding" "0016233=telomere capping, 0022008=neurogenesis, 0007143=female meiotic division, 0051276=chromosome organization" "0005730=nucleolus, 0000785=chromatin, 0000775=chromosome, centromeric region, 0035012=polytene chromosome, telomeric region, 0005700=polytene chromosome, 0005701=polytene chromosome chromocenter, 0005634=nucleus" "HP6, UMBREA, umbrea, CG15636, UMB, Umbrea" "IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR008251=Chromo shadow domain" CG15636 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,neuroanatomy defective,viable,visible" "eye,polytene chromosome, telomeric regionG61,embryonic/larval salivary gland,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,polar body nucleus" FBgn0034705 CG11170 http://flybase.net/reports/FBgn0034705.html protein_coding_gene CG30279 "IPR022049=FAM69, protein-kinase domain" CG11170 16-Dec-15 2015_12 "ENSDARG00000012816(c3orf58a),ENSDARG00000055629(c3orf58b),ENSDARG00000061747(LOC569232)" ENSXETG00000001626(C3orf58) viable FBgn0084432 Su(dpp)YE12 Su(dpp)YE12 http://flybase.net/reports/FBgn0084432.html gene 16-Dec-15 2015_12 "viable,male sterile" FBgn0053373 5SrRNA:CR33373 5SrRNA:CR33373 http://flybase.net/reports/FBgn0053373.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33373 CR33373 16-Dec-15 2015_12 FBgn0025378 CG3795 http://flybase.net/reports/FBgn0025378.html FBgn0063223 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BcDNA:GH24985, EG:9D2.4, SP160" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG3795 16-Dec-15 2015_12 viable FBgn0026335 Su(tor)278-22 Su(tor)278-22 http://flybase.net/reports/FBgn0026335.html gene 16-Dec-15 2015_12 FBgn0266426 Dfd::Scr Dfd::Scr http://flybase.net/reports/FBgn0266426.html engineered_fusion_gene Dfd[Scr] 16-Dec-15 2015_12 "embryonic mesothoracic segment,embryonic metathoracic segment,denticle,ectopic,cirri" FBgn0083294 E(smoDN)198 Enhancer of smoDN 198 http://flybase.net/reports/FBgn0083294.html gene 16-Dec-15 2015_12 FBgn0259446 C246 http://flybase.net/reports/FBgn0259446.html gene 16-Dec-15 2015_12 "visible,lethal" "wing,chaeta" FBgn0263734 dco::Hsap\CSNK1E http://flybase.net/reports/FBgn0263734.html engineered_fusion_gene ckIepsilon-dbt 16-Dec-15 2015_12 locomotor rhythm defective FBgn0052238 CG32238 http://flybase.net/reports/FBgn0052238.html FBgn0035565 protein_coding_gene 0004835=tubulin-tyrosine ligase activity "0018095=protein polyglutamylation, 0018166=C-terminal protein-tyrosinylation" CG7474 "IPR027750=Tubulin polyglutamylase TTLL1, IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase" CG32238 16-Dec-15 2015_12 ENSDARG00000009029 WBGene00044187(ttll-9) ENSXETG00000027373(TTLL2) ENSMUSG00000022442(Ttll1) ENSG00000100271(TTLL1) viable FBgn0000287 salr spalt-related http://flybase.net/reports/FBgn0000287.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0048098=antennal joint development, 0007605=sensory perception of sound, 0007423=sensory organ development, 0008586=imaginal disc-derived wing vein morphogenesis, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0030539=male genitalia development, 0008584=male gonad development" 0005634=nucleus "salR, spalt related, Spalt, Salr, spalt, Chorion factor 3, 32F, sal-related, Cf3, Spalt-related, sal, CG4881, sal related, sal-r, Sal-r" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4881 16-Dec-15 2015_12 ENSMUSG00000031665(Sall1) " embryonic stage -- adult stage , larval stage | third instar " dorsal mesothoracic disc | restricted

" embryonic stage | stage 16 , embryonic stage | late , larval stage , larval stage | third instar " " embryonic/larval posterior spiracle

, embryonic central nervous system

, larval central nervous system

, dorsal mesothoracic disc | dorsal comparment & medial

, imaginal disc

, dorsal mesothoracic disc | restricted

" "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "macrochaeta,ectopic,anterior dorsocentral bristle,anterior postalar bristle,precursor,posterior postalar bristle,anterior notopleural bristle,posterior notopleural bristle,dorsocentral bristle,notopleural bristle,postalar bristle,wing vein L2,wing vein L5,posterior dorsocentral bristle,posterior scutellar bristle,adult thorax & macrochaetaBx-MS1096,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,wing vein,wing" FBgn0002891 mus205 mutagen-sensitive 205 http://flybase.net/reports/FBgn0002891.html FBgn0033223 protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0008408=3'-5' exonuclease activity, 0003677=DNA binding, 0000166=nucleotide binding" "0019985=translesion synthesis, 0000724=double-strand break repair via homologous recombination, 0006260=DNA replication, 0006297=nucleotide-excision repair, DNA gap filling" "0005634=nucleus, 0005694=chromosome, 0016035=zeta DNA polymerase complex" "CG1925, Dmpolzeta, mus 205, rev3, mus(2)205, AAF59191, DhRev3, 154926_at, Mus205, DmREV3, mus-205" "IPR012337=Ribonuclease H-like domain, IPR006133=DNA-directed DNA polymerase, family B, exonuclease domain, IPR006134=DNA-directed DNA polymerase, family B, multifunctional domain, IPR017964=DNA-directed DNA polymerase, family B, conserved site, IPR025687=C4-type zinc-finger of DNA polymerase delta, IPR023211=DNA polymerase, palm domain, IPR030559=DNA polymerase zeta catalytic subunit, IPR006172=DNA-directed DNA polymerase, family B" CG1925 16-Dec-15 2015_12 YPL167C(REV3) WBGene00021344(Y37B11A.2) ENSMUSG00000019841(Rev3l) ENSG00000009413(REV3L) "chemical sensitive,radiation sensitive,DNA repair defective,recessive,viable,radiation resistant,fertile,maternal effect,female fertile,reduced" FBgn0014202 l(1)16Fi lethal (1) 16Fi http://flybase.net/reports/FBgn0014202.html gene 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0004026 wtl weltlike http://flybase.net/reports/FBgn0004026.html gene 16-Dec-15 2015_12 female sterile "eye,arista,wing" FBgn0082343 HM515 HM515 http://flybase.net/reports/FBgn0082343.html gene 16-Dec-15 2015_12 FBgn0263073 GS5246 http://flybase.net/reports/FBgn0263073.html gene 16-Dec-15 2015_12 FBgn0002878 mus101 mutagen-sensitive 101 http://flybase.net/reports/FBgn0002878.html FBgn0030515 protein_coding_gene "0007067=mitotic nuclear division, 0048477=oogenesis, 0033314=mitotic DNA replication checkpoint, 0007095=mitotic G2 DNA damage checkpoint" "fs(1)K451, Mus101, anon-WO0148202.1, mus(1)101, mus-101, mus 101, CG11156, TOPBP1, DmMus101" IPR001357=BRCT domain CG11156 16-Dec-15 2015_12 ENSDARG00000005606(paxip1) WBGene00009507(mus-101) ENSXETG00000001854(TOPBP1) ENSMUSG00000032555(Topbp1) ENSG00000163781(TOPBP1) embryonic stage | 0-4 hr "chemical sensitive,radiation sensitive,DNA repair defective,wild-type,lethal,recessive,female sterile,partially,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,female sterile germline-dependent,viable" "imaginal disc,mitosis & nuclear chromosome,heterochromatin,chromatin" FBgn0001054 Fs(3)Kar Female sterile (3) Kartal http://flybase.net/reports/FBgn0001054.html gene 0040016=embryonic cleavage "Fs(3)Kartal, Fs(3)Sz27, Kar" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0016737 SR3-7 SR3-7 http://flybase.net/reports/FBgn0016737.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265160 CR44229 http://flybase.net/reports/FBgn0265160.html non_protein_coding_gene CG44229 CR44229 16-Dec-15 2015_12 FBgn0060970 l(3)SzB90Co lethal (3) SzB90Co http://flybase.net/reports/FBgn0060970.html gene "l(3)S029701b, 0297/01" 16-Dec-15 2015_12 lethal FBgn0263829 CG34334 http://flybase.net/reports/FBgn0263829.html "FBgn0085363, FBgn0031203" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "cg9561, CG9561" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG34334 16-Dec-15 2015_12 FBgn0027630 ms(1)66 ms(1)66 http://flybase.net/reports/FBgn0027630.html gene 16-Dec-15 2015_12 male sterile meiosis I FBgn0032803 CG13082 http://flybase.net/reports/FBgn0032803.html protein_coding_gene CG13082 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0065900 l(2)SH0201 lethal (2) SH0201 http://flybase.net/reports/FBgn0065900.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002390 l(3)93Dg lethal (3) 93Dg http://flybase.net/reports/FBgn0002390.html gene "l(3)er13, er13" 16-Dec-15 2015_12 "lethal,recessive" FBgn0067778 els ellsworth http://flybase.net/reports/FBgn0067778.html gene "0045450=bicoid mRNA localization, 0045451=pole plasm oskar mRNA localization" 16-Dec-15 2015_12 female sterile "nurse cell,germline clone,oocyte,egg,embryonic head" FBgn0051017 PH4ë±NE3 prolyl-4-hydroxylase-alpha NE3 http://flybase.net/reports/FBgn0051017.html FBgn0039791 protein_coding_gene "0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0005783=endoplasmic reticulum, 0016222=procollagen-proline 4-dioxygenase complex" "CG9708, CG31017" "IPR011990=Tetratricopeptide-like helical domain, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG31017 16-Dec-15 2015_12 viable FBgn0001542 l(1)14Ea lethal (1) 14Ea http://flybase.net/reports/FBgn0001542.html gene "l(1)k22a, k22a" 16-Dec-15 2015_12 lethal FBgn0004513 Mdr65 Multi drug resistance 65 http://flybase.net/reports/FBgn0004513.html protein_coding_gene "0008559=xenobiotic-transporting ATPase activity, 0005524=ATP binding, 0015238=drug transmembrane transporter activity, 0015562=efflux transmembrane transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0060857=establishment of glial blood-brain barrier, 0055085=transmembrane transport, 0031427=response to methotrexate, 0042908=xenobiotic transport" "0005887=integral component of plasma membrane, 0043190=ATP-binding cassette (ABC) transporter complex, 0005919=pleated septate junction, 0005886=plasma membrane, 0016021=integral component of membrane" "Multiple drug resistance 65, CG10181, mdr65, P-gp, MDR65, P-glycoprotein65-Dm, P-glycoprotein, Mdr65A" "IPR003439=ABC transporter-like, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10181 16-Dec-15 2015_12 YKL209C(STE6) viable FBgn0036531 CG6244 http://flybase.net/reports/FBgn0036531.html protein_coding_gene IPR007808=Transcription elongation factor 1 CG6244 16-Dec-15 2015_12 YKL160W(ELF1) ENSXETG00000016731(TGas034f20.1) FBgn0030907 CG15058 http://flybase.net/reports/FBgn0030907.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029100 anon-89Bc anon-89Bc http://flybase.net/reports/FBgn0029100.html gene 16-Dec-15 2015_12 FBgn0065734 l(2)SH0545 lethal (2) SH0545 http://flybase.net/reports/FBgn0065734.html gene l(2)SH2 0545 16-Dec-15 2015_12 "lethal,recessive" FBgn0014880 Sry-ë_::Sry-ë« Sry-ë_::Sry-ë« http://flybase.net/reports/FBgn0014880.html engineered_fusion_gene 16-Dec-15 2015_12 female sterile FBgn0058139 CG40139 http://flybase.net/reports/FBgn0058139.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032554 CG15278 http://flybase.net/reports/FBgn0032554.html FBgn0045116 protein_coding_gene "NEST:bs32h08, bs32h08.y1" CG15278 16-Dec-15 2015_12 viable FBgn0037252 CG14650 http://flybase.net/reports/FBgn0037252.html FBan0014650 protein_coding_gene 0009408=response to heat IPR001623=DnaJ domain CG14650 16-Dec-15 2015_12 WBGene00001023(dnj-5) viable FBgn0263084 HP1Lcsd Heterochromatin Protein 1L chromoshadow domain http://flybase.net/reports/FBgn0263084.html protein_coding_gene 0003682=chromatin binding 0051276=chromosome organization "0005634=nucleus, 0000785=chromatin" "HP1Lcsd, lincRNA.384, CG43352" "IPR016197=Chromo domain-like, IPR008251=Chromo shadow domain" CG43352 16-Dec-15 2015_12 FBgn0260320 GSd404 http://flybase.net/reports/FBgn0260320.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "intersegmental nerve,segmental nerve" FBgn0031644 CG15625 http://flybase.net/reports/FBgn0031644.html protein_coding_gene "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG15625 16-Dec-15 2015_12 "viable,fertile" FBgn0264912 CR44103 http://flybase.net/reports/FBgn0264912.html non_protein_coding_gene lincRNA.679 CR44103 16-Dec-15 2015_12 FBgn0027262 l(1)G0228 lethal (1) G0228 http://flybase.net/reports/FBgn0027262.html gene 16-Dec-15 2015_12 "lethal,recessive" adult abdomen FBgn0020857 fs(2)261404 female sterile(2)261404 http://flybase.net/reports/FBgn0020857.html gene fs(2)A 16-Dec-15 2015_12 "female sterile,recessive" FBgn0260800 l(2)GSG317 http://flybase.net/reports/FBgn0260800.html gene 16-Dec-15 2015_12 lethal FBgn0034671 CG13494 http://flybase.net/reports/FBgn0034671.html FBgn0063322 protein_coding_gene BcDNA:AT17606 CG13494 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0014869 Pglym78 Phosphoglyceromutase http://flybase.net/reports/FBgn0014869.html protein_coding_gene 0004619=phosphoglycerate mutase activity "0007520=myoblast fusion, 0006096=glycolytic process, 0007525=somatic muscle development" "0031430=M band, 0030018=Z disc" "PGLYM, Pglym, CG1721, pglym78, phosphoglycerol mutase, phosphoglyceromutase, phosphoglycerate mutase, PGAM" "IPR013078=Histidine phosphatase superfamily, clade-1, IPR005952=Phosphoglycerate mutase 1, IPR001345=Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR029033=Histidine phosphatase superfamily" CG1721 16-Dec-15 2015_12 "ENSDARG00000014068(pgam1b),ENSDARG00000005423(pgam1a),ENSDARG00000057571(pgam2)" YKL152C(GPM1) "ENSXETG00000003433(),ENSXETG00000018980(pgam2)" "ENSMUSG00000011752(Pgam1),ENSMUSG00000020475(Pgam2)" "ENSG00000220515,ENSG00000171314(PGAM1),ENSG00000186076,ENSG00000164708(PGAM2)" "embryonic/larval somatic muscle,embryonic myoblast,segment border muscle,A1-7 dorsal acute muscle 1" FBgn0011646 Low Lightener of white http://flybase.net/reports/FBgn0011646.html gene 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" pigment cell FBgn0019810 ftz::RpP1 ftz::RpP1 http://flybase.net/reports/FBgn0019810.html engineered_fusion_gene ftz::RpA-70 16-Dec-15 2015_12 FBgn0013595 l(3)A6-3-56 lethal (3) A6-3-56 http://flybase.net/reports/FBgn0013595.html gene 16-Dec-15 2015_12 lethal FBgn0028411 Nxt1 NTF2-related export protein 1 http://flybase.net/reports/FBgn0028411.html protein_coding_gene "0045824=negative regulation of innate immune response, 0009267=cellular response to starvation, 0006406=mRNA export from nucleus, 0006611=protein export from nucleus, 0006409=tRNA export from nucleus, 0016973=poly(A)+ mRNA export from nucleus, 0050829=defense response to Gram-negative bacterium, 0006408=snRNA export from nucleus" "0005737=cytoplasm, 0005634=nucleus, 0005654=nucleoplasm, 0005635=nuclear envelope" "dmNXT, CG12752, DmNXT1, dmNXT1, nxt1, p15, dmP15, Nxt, dNxt" "IPR018222=Nuclear transport factor 2, eukaryote, IPR002075=Nuclear transport factor 2" CG12752 16-Dec-15 2015_12 ENSDARG00000061527(nxt2) WBGene00003836(nxt-1) "ENSMUSG00000036992(Nxt1),ENSMUSG00000042271(Nxt2)" "ENSG00000101888(NXT2),ENSG00000132661(NXT1)" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" mesothoracic tergum DRSC04630 I 2.127790577 -0.39622592 -0.673188721 1.417723194 0.176290143 0.803750775 FBgn0023034 l(2)46Ei lethal (2) 46Ei http://flybase.net/reports/FBgn0023034.html gene "S, Complementation group S" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,some die during larval stage" FBgn0261111 BHD Birt-Hogg-Dube homolog http://flybase.net/reports/FBgn0261111.html "FBgn0069982, FBgn0035752" protein_coding_gene "1901840=negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding, 0030718=germ-line stem cell maintenance, 1901837=negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" "0005730=nucleolus, 0005737=cytoplasm" "Folliculin homolog, CG8616, CT25610, GABA A receptor beta3-like, Birt-Hogg-Dube, DBHD, dFLCN, Birt-Hogg-Dube syndrome" IPR021713=Folliculin CG8616 16-Dec-15 2015_12 ENSDARG00000062385(flcn) WBGene00017699(F22D3.2) ENSXETG00000005745(flcn) ENSMUSG00000032633(Flcn) ENSG00000154803(FLCN) FBgn0266670 Sec5 Sec5 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266670.html "FBgn0266610, FBgn0031537" protein_coding_gene 0017137=Rab GTPase binding "0043001=Golgi to plasma membrane protein transport, 0071896=protein localization to adherens junction, 0035147=branch fusion, open tracheal system, 0016192=vesicle-mediated transport, 0010629=negative regulation of gene expression, 0072659=protein localization to plasma membrane, 0045056=transcytosis, 0006893=Golgi to plasma membrane transport, 0016081=synaptic vesicle docking, 0007269=neurotransmitter secretion, 0016080=synaptic vesicle targeting, 0007298=border follicle cell migration, 0000281=mitotic cytokinesis, 0007349=cellularization, 0048215=positive regulation of Golgi vesicle fusion to target membrane, 0048599=oocyte development, 0072697=protein localization to cell cortex, 0032456=endocytic recycling, 0045087=innate immune response" "0016028=rhabdomere, 0035003=subapical complex, 0030136=clathrin-coated vesicle, 0005737=cytoplasm, 0005886=plasma membrane, 0000145=exocyst, 0005938=cell cortex, 0005642=annulate lamellae, 0055037=recycling endosome" "SEC5, Sec5p, sec5, CG8843, Sec-5, dsec5" "IPR013783=Immunoglobulin-like fold, IPR029175=Exocyst complex component EXOC2/Sec5, IPR002909=IPT domain, IPR014756=Immunoglobulin E-set" CG8843 16-Dec-15 2015_12 ENSDARG00000055610(exoc2) WBGene00004752(sec-5) ENSXETG00000011411(EXOC2) ENSMUSG00000021357(Exoc2) ENSG00000112685(EXOC2) FBgn0021789 l(2)rH280 lethal (2) rH280 http://flybase.net/reports/FBgn0021789.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069071 zih ziehharmonika http://flybase.net/reports/FBgn0069071.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect,filzkorper,embryonic segment" FBgn0032472 CG9928 http://flybase.net/reports/FBgn0032472.html FBgn0046995 protein_coding_gene "BcDNA:RH70154, CT27834" CG9928 16-Dec-15 2015_12 viable FBgn0067056 Q7 Q7 http://flybase.net/reports/FBgn0067056.html gene 16-Dec-15 2015_12 "visible,lethal,viable" eye FBgn0031410 CG17237 http://flybase.net/reports/FBgn0031410.html FBgn0063331 protein_coding_gene "0042623=ATPase activity, coupled" 0016459=myosin complex "DmAAF51272, BcDNA:AT15471" IPR011992=EF-hand domain pair CG17237 16-Dec-15 2015_12 FBgn0065614 l(2)SH0824 lethal (2) SH0824 http://flybase.net/reports/FBgn0065614.html gene l(2)SH2 0824 16-Dec-15 2015_12 "lethal,recessive" FBgn0264090 CG43759 http://flybase.net/reports/FBgn0264090.html "FBgn0052541, FBgn0030977, FBgn0030978, FBgn0260232" protein_coding_gene 0002121=inter-male aggressive behavior "CG14188, CG12527, LD15404, CG32541, CG42506, EP(X)1644" CG43759 16-Dec-15 2015_12 FBgn0066292 CheB42c Chemosensory protein B 42c http://flybase.net/reports/FBgn0066292.html "FBgn0033119, FBgn0053350" protein_coding_gene 0008289=lipid binding "0007606=sensory perception of chemical stimulus, 0043695=detection of pheromone" "0005576=extracellular region, 0005615=extracellular space" "CheB42c, CG15241, CG33350" "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG33350 16-Dec-15 2015_12 "viable,lethal" FBgn0023058 l(1)2Ed lethal (1) 2Ed http://flybase.net/reports/FBgn0023058.html gene E3/34.12 16-Dec-15 2015_12 "lethal,recessive" FBgn0000656 fil fine lash http://flybase.net/reports/FBgn0000656.html gene 16-Dec-15 2015_12 "viable,fertile,visible" "macrochaeta,eye" FBgn0266861 CR45322 http://flybase.net/reports/FBgn0266861.html non_protein_coding_gene CR45322 16-Dec-15 2015_12 FBgn0032374 CG14931 http://flybase.net/reports/FBgn0032374.html protein_coding_gene CG14931 16-Dec-15 2015_12 viable FBgn0035484 CG11594 http://flybase.net/reports/FBgn0035484.html protein_coding_gene "0016773=phosphotransferase activity, alcohol group as acceptor" "0005975=carbohydrate metabolic process, 0034976=response to endoplasmic reticulum stress" "IPR000577=Carbohydrate kinase, FGGY, IPR018485=Carbohydrate kinase, FGGY, C-terminal, IPR006003=Carbohydrate kinase, FGGY-related, IPR018484=Carbohydrate kinase, FGGY, N-terminal" CG11594 16-Dec-15 2015_12 YDR109C() ENSXETG00000008887(FGGY) ENSMUSG00000028573(Fggy) ENSG00000172456(FGGY) viable FBgn0030519 CG11151 http://flybase.net/reports/FBgn0030519.html protein_coding_gene 0004303=estradiol 17-beta-dehydrogenase activity "0005811=lipid particle, 0005777=peroxisome" "transcript 2, 2" IPR003033=SCP2 sterol-binding domain CG11151 16-Dec-15 2015_12 ENSDARG00000036496(zgc:101621) WBGene00003773(nlt-1) ENSMUSG00000027431(1700010M22Rik) ENSG00000132631(C20orf79) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC19387 I 2.264954329 -0.438673305 -0.114434953 0.435375769 -1.119534833 0.781024737 FBgn0005678 mcd1 muscle cell death 1 http://flybase.net/reports/FBgn0005678.html gene mcd-1 16-Dec-15 2015_12 "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "muscle 18a,maternal effect,muscle 18b" FBgn0013521 l(1)x lethal (1) x http://flybase.net/reports/FBgn0013521.html gene l(x) 16-Dec-15 2015_12 "lethal,recessive" FBgn0065756 l(2)SH0488 lethal (2) SH0488 http://flybase.net/reports/FBgn0065756.html gene l(2)SH2 0488 16-Dec-15 2015_12 "lethal,recessive" FBgn0022367 Pt-6 Larval protein-6 http://flybase.net/reports/FBgn0022367.html gene 16-Dec-15 2015_12 FBgn0260287 GSd451 http://flybase.net/reports/FBgn0260287.html gene 16-Dec-15 2015_12 lethal FBgn0034664 CG4377 http://flybase.net/reports/FBgn0034664.html protein_coding_gene CT14296 IPR008472=Domain of unknown function DUF753 CG4377 16-Dec-15 2015_12 viable FBgn0023066 l(1)20BFa lethal (1) 20BFa http://flybase.net/reports/FBgn0023066.html gene 400C20a 16-Dec-15 2015_12 "lethal,recessive" FBgn0013268 Eip4F Eip4F http://flybase.net/reports/FBgn0013268.html gene 4F 16-Dec-15 2015_12 FBgn0060773 l(3)S061308 lethal (3) S061308 http://flybase.net/reports/FBgn0060773.html gene 0613/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal" FBgn0040707 CG15430 http://flybase.net/reports/FBgn0040707.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034052 CG8299 http://flybase.net/reports/FBgn0034052.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP65 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG8299 16-Dec-15 2015_12 "ENSDARG00000055014(LOC565078),ENSDARG00000038891(LOC560023)" viable FBgn0259297 EP-232 http://flybase.net/reports/FBgn0259297.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0015481 l(2)45Cb lethal (2) 45Cb http://flybase.net/reports/FBgn0015481.html gene 16-Dec-15 2015_12 lethal FBgn0045852 ham hamlet http://flybase.net/reports/FBgn0045852.html "FBgn0032710, FBgn0032711, FBgn0040991, FBgn0051753" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0008285=negative regulation of cell proliferation, 0014017=neuroblast fate commitment, 0048814=regulation of dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated, 0048666=neuron development, 0048813=dendrite morphogenesis, 0007423=sensory organ development" 0005634=nucleus "Hamlet, CG15907, Ham, HAM_DROME, CG10568, CG31753, CG15906" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR030413=Evi1/Prdm16, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG31753 16-Dec-15 2015_12 WBGene00001207(egl-43) ENSXETG00000012050(PRDM16) "ENSMUSG00000039410(Prdm16),ENSMUSG00000027684(Mecom)" "ENSG00000085276(MECOM),ENSG00000142611(PRDM16)" "viable,neuroanatomy defective,visible,decreased cell number,decreased cell size" "multidendritic neuron,supernumerary,dorsal abdominal cluster,eo neuron,trichogen cell,ectopic,tormogen cell,somatic clone,embryonic/larval nervous system,abdominal ventral sensillum campaniformium vc4a,secondary neuroblast,chaeta,type II neuroblast,type I neuroblast,ganglion mother cell" DRSC02070 K 0.544462478 0.908231016 -0.347781259 0.546755864 1.575814222 0.329884486 FBgn0039238 CG7016 http://flybase.net/reports/FBgn0039238.html protein_coding_gene CG7016 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0082351 HM385 HM385 http://flybase.net/reports/FBgn0082351.html gene 16-Dec-15 2015_12 FBgn0262685 CG43155 http://flybase.net/reports/FBgn0262685.html "FBgn0030302, FBgn0030303, FBgn0043906, FBgn0043915, FBgn0043916" protein_coding_gene "0005252=open rectifier potassium channel activity, 0005267=potassium channel activity" 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "anon-WO0109301.52, CG15194, CG1756, anon-WO0109301.9, anon-WO0109301.51" "IPR013099=Potassium channel domain, IPR003280=Two pore domain potassium channel" CG43155 16-Dec-15 2015_12 DRSC19777 K 0.856439848 0.672049348 -0.083395298 0.06439373 0.615555262 -1.797781903 FBgn0084019 CG41457 http://flybase.net/reports/FBgn0084019.html FBan0041457 protein_coding_gene 16-Dec-15 2015_12 FBgn0036602 CG13042 http://flybase.net/reports/FBgn0036602.html protein_coding_gene IPR007614=Retinin-like protein CG13042 16-Dec-15 2015_12 viable FBgn0011815 mei-269 mei-269 http://flybase.net/reports/FBgn0011815.html gene 16-Dec-15 2015_12 FBgn0060386 l(3)S134306a lethal (3) S134306a http://flybase.net/reports/FBgn0060386.html gene 1343/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0027608 CG2082 http://flybase.net/reports/FBgn0027608.html protein_coding_gene BcDNA:GH02439 "IPR029058=Alpha/Beta hydrolase fold, IPR004142=NDRG" CG2082 16-Dec-15 2015_12 WBGene00014213(ZK1073.1) "viable,fertile,partially lethal - majority die" DRSC12125 E 0.014805064 0.822488474 3.187014626 0.687041031 -0.885840314 -0.544545221 FBgn0024224 ird10 immune response deficient 10 http://flybase.net/reports/FBgn0024224.html gene 0006963=positive regulation of antibacterial peptide biosynthetic process ird 16-Dec-15 2015_12 "lethal,recessive" FBgn0033735 CG8525 http://flybase.net/reports/FBgn0033735.html protein_coding_gene 0004139=deoxyribose-phosphate aldolase activity 0009264=deoxyribonucleotide catabolic process 0005737=cytoplasm "IPR002915=DeoC/FbaB/ lacD aldolase, IPR011343=Deoxyribose-phosphate aldolase, IPR013785=Aldolase-type TIM barrel" CG8525 16-Dec-15 2015_12 ENSDARG00000005897(dera) WBGene00017283(F09E5.3) ENSMUSG00000030225(Dera) ENSG00000023697(DERA) "viable,fertile" FBgn0035346 CG1146 http://flybase.net/reports/FBgn0035346.html protein_coding_gene CG1146 16-Dec-15 2015_12 viable DRSC08189 E 0.732530614 0.410930236 -0.056289523 1.517949701 -0.018094121 -0.701037578 FBgn0267941 CR46221 http://flybase.net/reports/FBgn0267941.html non_protein_coding_gene lincRNA.688 CR46221 16-Dec-15 2015_12 FBgn0065684 l(2)SH0660 lethal (2) SH0660 http://flybase.net/reports/FBgn0065684.html gene l(2)SH2 0660 16-Dec-15 2015_12 "lethal,recessive" FBgn0085350 inaF-C inaF-C http://flybase.net/reports/FBgn0085350.html FBgn0023077 protein_coding_gene 0016247=channel regulator activity 0042391=regulation of membrane potential 0016020=membrane "CG34321, InaF, INAF, inaF" "IPR029162=TRP-interacting helix, InaF motif" CG34321 16-Dec-15 2015_12 FBgn0034623 CG9822 http://flybase.net/reports/FBgn0034623.html protein_coding_gene 0005576=extracellular region Agr-like "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG9822 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0001342 l(1)1Bk lethal (1) 1Bk http://flybase.net/reports/FBgn0001342.html gene HM441 16-Dec-15 2015_12 " adult stage , embryonic stage " "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025494 l(3)82CDc lethal (3) 82CDc http://flybase.net/reports/FBgn0025494.html gene 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0083001 snoRNA:ë¬28S-1192a snoRNA:ë¬28S-1192a http://flybase.net/reports/FBgn0083001.html snoRNA_gene "Psi 28S-1192a, Psi28S-1192a, CR34597, psi28S-1192a" CR34597 16-Dec-15 2015_12 FBgn0260002 snoRNA:Me28S-U2134b http://flybase.net/reports/FBgn0260002.html "FBgn0086050, FBgn0082164" snoRNA_gene "Me28S-Um2134b, snoRNA:U34, CR34679" CR34679 16-Dec-15 2015_12 FBgn0037291 CG14662 http://flybase.net/reports/FBgn0037291.html protein_coding_gene CT34440 CG14662 16-Dec-15 2015_12 viable FBgn0266133 c105 http://flybase.net/reports/FBgn0266133.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0023120 anon-10An anon-10An http://flybase.net/reports/FBgn0023120.html gene 6 16-Dec-15 2015_12 FBgn0015935 eg-1 eg-1 http://flybase.net/reports/FBgn0015935.html gene 0003725=double-stranded RNA binding unnamed 16-Dec-15 2015_12 FBgn0052022 CG32022 http://flybase.net/reports/FBgn0052022.html FBgn0063743 protein_coding_gene "0071816=tail-anchored membrane protein insertion into ER membrane, 0048477=oogenesis" "CG5950, BcDNA:AT11343, Wrb, Chd5" IPR028945=WRB/Get1 family CG32022 16-Dec-15 2015_12 ENSDARG00000024641 ENSXETG00000023739(Q6DD99_XENTR) ENSMUSG00000023147(Wrb) ENSG00000182093(WRB) viable "nurse cell,germline clone,ring canal" FBgn0085430 CG34401 http://flybase.net/reports/FBgn0085430.html "FBgn0040884, FBgn0030972, FBgn0030971, FBgn0040883, FBgn0052542" protein_coding_gene 0008270=zinc ion binding "CG17757, CG7307, CG7317, CG32542, CG15037" "IPR007527=Zinc finger, SWIM-type" CG34401 16-Dec-15 2015_12 ENSDARG00000055900(si:ch73-38p6.1) WBGene00004140(pqn-55) ENSXETG00000010000(KIAA0913) ENSMUSG00000021819(2310021P13Rik) ENSG00000214655(KIAA0913) FBgn0051855 CG31855 http://flybase.net/reports/FBgn0051855.html FBgn0032510 protein_coding_gene CG6537 "IPR018276=Ubiquitin ligase, Det1/DDB1-complexing" CG31855 16-Dec-15 2015_12 ENSMUSG00000074247(Dda1) ENSG00000130311(DDA1) viable DRSC02968 IK -1.499167095 -1.52824462 -0.10632783 0.163934937 -0.713775287 -1.672948211 FBgn0044065 GT7-45 GT7-45 http://flybase.net/reports/FBgn0044065.html gene 16-Dec-15 2015_12 viable FBgn0023415 Acp32CD Accessory gland protein 32CD http://flybase.net/reports/FBgn0023415.html protein_coding_gene 0005179=hormone activity "0045434=negative regulation of female receptivity, post-mating, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0005576=extracellular region" "Accessory gland-specific peptide 32CD, Accessory gland protein 32CD, CG4605" CG4605 16-Dec-15 2015_12 viable FBgn0028552 ë_Snap1 ë_ Soluble NSF attachment protein 1 http://flybase.net/reports/FBgn0028552.html protein_coding_gene 0005483=soluble NSF attachment protein activity "0048190=wing disc dorsal/ventral pattern formation, 0016082=synaptic vesicle priming, 0051726=regulation of cell cycle, 0006886=intracellular protein transport, 0007269=neurotransmitter secretion" "0031201=SNARE complex, 0005737=cytoplasm" "gamma-SNAP, gammaSnap, Gamma SNAP, gammaSNAP-2, CG3988, gSnap, gamma-Snap, gamma SNAP, gamma-soluble NSF attachment protein" "IPR000744=NSF attachment protein, IPR011990=Tetratricopeptide-like helical domain" CG3988 16-Dec-15 2015_12 "ENSDARG00000006617(napgl),ENSDARG00000043012" WBGene00013345(Y59A8B.8) ENSXETG00000004052(NAPG) ENSMUSG00000024581(Napg) ENSG00000134265(NAPG) viable DRSC04686 E 0.541054403 0.451811215 1.866366196 0.450903514 -0.302287334 -0.218194556 FBgn0036583 CG13055 http://flybase.net/reports/FBgn0036583.html protein_coding_gene CG13055 16-Dec-15 2015_12 viable FBgn0045460 MCP-PRE MCP Polycomb group response element http://flybase.net/reports/FBgn0045460.html regulatory_region "mcp, Mcp Element, PRE, Mcp, Mcp PRE, MCP, Mcp silencer, Polycomb responsive element (PRE) Mcp, Miscadastral" 16-Dec-15 2015_12 FBgn0002724 mex Malic enzyme modifier http://flybase.net/reports/FBgn0002724.html gene Mex 16-Dec-15 2015_12 FBgn0065177 l(3)SH009 lethal (3) SH009 http://flybase.net/reports/FBgn0065177.html gene l(2)SH3 009 16-Dec-15 2015_12 "lethal,recessive" FBgn0000360 Cp38 Chorion protein 38 http://flybase.net/reports/FBgn0000360.html FBgn0004940 protein_coding_gene 0005213=structural constituent of chorion 0007306=eggshell chorion assembly "CP38, Dms38, s38-1, Shell-38, cp38, s38, ACE1, CG11213, Chorion prot 38, S38, E3" IPR008449=Chorion S36/S38 CG11213 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage >=S10B , oogenesis stage | stage S10-14 " follicle cell

adult stage | female " ovary

{ v fs(1)A1059K1 } , ovary

{ 0 swa6 } , ovary

, ovary

{ v mus101K451 } " "electrophoretic variant,viable" FBgn0001199 His3 Histone H3 http://flybase.net/reports/FBgn0001199.html FBgn0062243 protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0000790=nuclear chromatin, 0035059=RCAF complex, 0000786=nucleosome, 0005700=polytene chromosome" "HisC, phosph-H3, DmeH3, Histone-H3, histone-3, pHistone3, his, Histone3, histone, histone-H3, Histone-3, H[[3]], H3, histone H3, phosphohistone H3, PH3, HH3, phosphorylated histone-H3, DmH3, anon-WO0118547.10, pH3, Ph3, h3, His, His3.2, histoneH3, H3 Histone, P~H3, histone 3, H3.3, H3 histone, his3, Histone 3, dH3, phospho-histone H3, H3.1, phosphorylated histone H3, phospho-Histone H3, replication-dependent histone 3, Phospho histone 3, Histone, core histone" "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" 16-Dec-15 2015_12 spermatogenesis && adult stage " Y chromosome loop

, spermatid

, protein body

, spermatocyte

" "lethal - all die before end of embryonic stage,homeotic,somatic clone" FBgn0262855 CG43219 http://flybase.net/reports/FBgn0262855.html protein_coding_gene DMG4-MB6.chr3L.36.014 CG43219 16-Dec-15 2015_12 FBgn0085743 CR40560 http://flybase.net/reports/FBgn0085743.html FBan0040560 rRNA_gene CR40560 16-Dec-15 2015_12 FBgn0062273 G192 G192 http://flybase.net/reports/FBgn0062273.html gene 0007173=epidermal growth factor receptor signaling pathway 16-Dec-15 2015_12 FBgn0039727 CG15523 http://flybase.net/reports/FBgn0039727.html protein_coding_gene Eif2b "IPR026847=Vacuolar protein sorting-associated protein 13, IPR026854=Vacuolar protein sorting-associated protein 13A, N-terminal domain" CG15523 16-Dec-15 2015_12 ENSXETG00000017855(VPS13B) ENSMUSG00000037646(Vps13b) ENSG00000132549(VPS13B) viable FBgn0085510 CG40715 http://flybase.net/reports/FBgn0085510.html FBan0040715 protein_coding_gene 16-Dec-15 2015_12 FBgn0261587 CG42697 http://flybase.net/reports/FBgn0261587.html protein_coding_gene CG42697 16-Dec-15 2015_12 learning defective FBgn0267345 l(4)7-M1365 lethal (4) 7-M1365 http://flybase.net/reports/FBgn0267345.html gene 16-Dec-15 2015_12 FBgn0267199 CR45639 http://flybase.net/reports/FBgn0267199.html non_protein_coding_gene CR45639 16-Dec-15 2015_12 FBgn0053196 dpy dumpy http://flybase.net/reports/FBgn0053196.html "FBgn0000488, FBgn0029129, FBgn0031612, FBgn0051724, FBgn0051725, FBgn0051726, FBgn0051727, FBgn0051964, FBgn0051965, FBgn0051966, FBgn0051967, FBgn0051968, FBgn0053000, FBgn0053195, FBgn0062896, FBgn0063623" protein_coding_gene "0005201=extracellular matrix structural constituent, 0005509=calcium ion binding, 0051539=4 iron, 4 sulfur cluster binding" "0007424=open tracheal system development, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0040005=chitin-based cuticle attachment to epithelium, 0046331=lateral inhibition, 0008362=chitin-based embryonic cuticle biosynthetic process" "0031012=extracellular matrix, 0005578=proteinaceous extracellular matrix" "BcDNA:SD02173, dp, CR33195, Mur24F, CG31965, CG33086, l(2)24Fd, DP, Mucin related 24F, Dp, CG31727, fibrillin-like, CG15637, DPY, olv[D], CT35799, Q8IQ18_DROME, CG33196, Dumpy, CG31968, CG31967, CG31726, CG31724, CG31725, CG31966, SP460, CG31964, CG33000" "IPR003645=Follistatin-like, N-terminal, IPR000742=EGF-like domain, IPR006150=Cysteine-rich repeat, IPR018097=EGF-like calcium-binding, conserved site, IPR001507=Zona pellucida domain, IPR024731=EGF domain, IPR026823=Complement Clr-like EGF domain, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR003651=Endonuclease III-like, iron-sulphur cluster loop motif, IPR001881=EGF-like calcium-binding domain, IPR023413=Green fluorescent protein-like" CG33196 16-Dec-15 2015_12 "visible,recessive,lethal,enhancer of variegation,dominant,suppressor of variegation,semidominant,immune response defective,somatic clone,cold sensitive,partially lethal - majority die,viable,reduced,wild-type,fertile,planar polarity defective" "adult thorax & adult epidermis,wing,presumptive embryonic/larval tracheal system,adult thorax,thorax,cerebral branch,ventral cephalic branch,pharyngeal branch,dorsal branch,visceral branch,lateral trunk anterior branch,lateral trunk posterior branch,leg,adult abdomen,dorsocentral bristle,mesothoracic tergum,sternopleural bristle,adult,wing blade,somatic clone,endocuticle,thorax & microchaeta,wing vein,macrochaeta,muscle attachment site,chaeta,supernumerary,trichogen cell" FBgn0262448 mir-279 mir-279 stem loop http://flybase.net/reports/FBgn0262448.html "FBgn0260633, FBgn0067714, FBgn0028049, FBgn0262308" miRNA_gene "0031987=locomotion involved in locomotory behavior, 0048190=wing disc dorsal/ventral pattern formation, 0001964=startle response, 0031047=gene silencing by RNA, 0048854=brain morphogenesis, 0045475=locomotor rhythm" "mir-279a, dme-mir-279, Mir-279, l(3)S096207, MiR-279, dme-miR-279-3p, miR, CR43015, 0962/07, CR33590, 279, miR279, miR-279, lethal (3) S096207, mir-279, dme-miR-279" CR43015 16-Dec-15 2015_12 FBgn0261916 Burdock\env http://flybase.net/reports/FBgn0261916.html transposable_element_gene env 16-Dec-15 2015_12 FBgn0039434 TwdlM TweedleM http://flybase.net/reports/FBgn0039434.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix CG5468 IPR004145=Domain of unknown function DUF243 CG5468 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0016662 HeT-A\gag gag http://flybase.net/reports/FBgn0016662.html FBgn0013980 transposable_element_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "0000781=chromosome, telomeric region, 0005634=nucleus, 0000784=nuclear chromosome, telomeric region" "Gag, Orf2, HeT-A Gag, HeT-A gag, GAG-like, HeT-A[mel] Gag, ORF, HeT-A\T, ORF1p, GAG, Orf1" "IPR001878=Zinc finger, CCHC-type, IPR006579=Pre-C2HC domain" 16-Dec-15 2015_12 FBgn0053242 Ste:CG33242 Ste:CG33242 http://flybase.net/reports/FBgn0053242.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG33242, CG32605" "IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR000704=Casein kinase II, regulatory subunit" CG33242 16-Dec-15 2015_12 FBgn0016883 l(2)39DEh lethal (2) 39DEh http://flybase.net/reports/FBgn0016883.html gene D95 16-Dec-15 2015_12 lethal FBgn0061061 l(3)S022242b lethal (3) S022242b http://flybase.net/reports/FBgn0061061.html gene 0222/42 16-Dec-15 2015_12 "lethal,recessive" FBgn0066127 E(sda)G E(sda)G http://flybase.net/reports/FBgn0066127.html gene Line G 16-Dec-15 2015_12 "lethal,recessive" FBgn0015936 elg elongatus http://flybase.net/reports/FBgn0015936.html gene 16-Dec-15 2015_12 FBgn0060390 l(3)S133804 lethal (3) S133804 http://flybase.net/reports/FBgn0060390.html gene 1338/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011063 l(1)Q16 lethal (1) Q16 http://flybase.net/reports/FBgn0011063.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0040629 CG18673 http://flybase.net/reports/FBgn0040629.html protein_coding_gene "0004089=carbonate dehydratase activity, 0008270=zinc ion binding" 0006730=one-carbon metabolic process "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class, IPR018338=Carbonic anhydrase, alpha-class, conserved site" CG18673 16-Dec-15 2015_12 "ENSDARG00000043589(LOC100330944),ENSDARG00000044512(LOC100333339)" WBGene00000283(cah-5) "ENSXETG00000022384(),ENSXETG00000016426(CA14)" "ENSMUSG00000079715,ENSMUSG00000028463(Car9)" viable FBgn0004215 l(3)84Fc lethal (3) 84Fc http://flybase.net/reports/FBgn0004215.html gene 16-Dec-15 2015_12 lethal FBgn0065744 l(2)SH0520 lethal (2) SH0520 http://flybase.net/reports/FBgn0065744.html gene l(2)SH2 0520 16-Dec-15 2015_12 "lethal,recessive" FBgn0067735 l(1)G0460 lethal (1) G0460 http://flybase.net/reports/FBgn0067735.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0260001 TK2 http://flybase.net/reports/FBgn0260001.html protein_coding_gene 0005737=cytoplasm 16-Dec-15 2015_12 FBgn0052537 CG32537 http://flybase.net/reports/FBgn0052537.html FBgn0031009 protein_coding_gene CG8020 CG32537 16-Dec-15 2015_12 viable DRSC20073 K 0.475083853 0.638240862 0.134488535 0.052061886 -0.478559526 -1.679502451 FBgn0085642 CG41418 http://flybase.net/reports/FBgn0085642.html FBan0041418 protein_coding_gene 16-Dec-15 2015_12 FBgn0028953 CG14478 http://flybase.net/reports/FBgn0028953.html FBgn0034222 protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior" "GENE 4, BEST:LD13441, gene 4" CG14478 16-Dec-15 2015_12 "ENSDARG00000045086,ENSDARG00000041671,ENSDARG00000036706,ENSDARG00000031385,ENSDARG00000038880" "behavior defective,recessive,viable" FBgn0260584 2L3267 http://flybase.net/reports/FBgn0260584.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0267107 CR45547 http://flybase.net/reports/FBgn0267107.html non_protein_coding_gene CR45547 16-Dec-15 2015_12 FBgn0005316 Mudd Muddled http://flybase.net/reports/FBgn0005316.html gene 0001654=eye development "Muddy, Mud" 16-Dec-15 2015_12 "male fertile,viable,male,poor,visible,dominant,eye color defective" "pigment cell,eye" FBgn0042152 CG18829 http://flybase.net/reports/FBgn0042152.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053182 Kdm4B Lysine (K)-specific demethylase 4B http://flybase.net/reports/FBgn0053182.html FBgn0033804 protein_coding_gene "0051864=histone demethylase activity (H3-K36 specific), 0032454=histone demethylase activity (H3-K9 specific)" "0016577=histone demethylation, 0033169=histone H3-K9 demethylation, 0045892=negative regulation of transcription, DNA-templated, 0070544=histone H3-K36 demethylation" 0005634=nucleus "Histone demethylase 4B, CG33182, CG4037, dKDM4B, dJMJD2(2), KDM4B, dKdm4B" "IPR003347=JmjC domain, IPR003349=JmjN domain" CG33182 16-Dec-15 2015_12 "ENSDARG00000018782(LOC100003413),ENSDARG00000019103(jmjd2al),ENSDARG00000042729(kdm4b)" ENSMUSG00000053914(Kdm4d) "ENSG00000066135(KDM4A),ENSG00000107077(KDM4C),ENSG00000127663(KDM4B)" "viable,fertile,radiation sensitive,dominant" embryonic/larval hemocyte | third instar larval stage FBgn0039831 CG12054 http://flybase.net/reports/FBgn0039831.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG12054 16-Dec-15 2015_12 WBGene00013465(Y67H2A.10) DRSC23137 IEK -0.238862644 -2.001025039 0.717613883 3.777608237 -1.687718773 1.232026842 FBgn0034503 MED8 Mediator complex subunit 8 http://flybase.net/reports/FBgn0034503.html FBgn0050140 protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0051726=regulation of cell cycle, 0006357=regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" 0016592=mediator complex "Med8/ARC32, dARC32, CG13867, Arc32, ARC32, CG30140" "IPR019364=Mediator complex, subunit Med8, fungi/metazoa" CG13867 16-Dec-15 2015_12 ENSDARG00000008064 WBGene00007013(mdt-8) ENSXETG00000009582(MED8) ENSMUSG00000006392(Med8) ENSG00000159479(MED8) "viable,visible" "chaeta,supernumerary,mesothoracic tergum" DRSC06426 IE -0.290937039 2.253608859 -3.038851375 -0.258714591 0.435619361 0.32275711 FBgn0036380 CG8757 http://flybase.net/reports/FBgn0036380.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process FOHSDR "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site" CG8757 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) viable FBgn0264281 Su(Mir)2A2-1 http://flybase.net/reports/FBgn0264281.html gene 16-Dec-15 2015_12 lethal FBgn0263844 CR43705 http://flybase.net/reports/FBgn0263844.html non_protein_coding_gene CR43705 16-Dec-15 2015_12 FBgn0000780 fs(1)A1509 female sterile (1) A1509 http://flybase.net/reports/FBgn0000780.html gene fs(1)1509 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,recessive,female sterile" gastrula embryo FBgn0265270 CR43239 http://flybase.net/reports/FBgn0265270.html "FBgn0262884, FBgn0066900" non_protein_coding_gene "anon-SAGE:Wang-098, lincRNA.170" CR43239 16-Dec-15 2015_12 FBgn0051320 HEATR2 HEAT repeat containing 2 http://flybase.net/reports/FBgn0051320.html FBgn0045167 protein_coding_gene 0045505=dynein intermediate chain binding "0036158=outer dynein arm assembly, 0030317=sperm motility, 0007605=sensory perception of sound, 0036159=inner dynein arm assembly, 0008344=adult locomotory behavior" 0005737=cytoplasm "NEST:bs27f03, CG31320" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG31320 16-Dec-15 2015_12 ENSMUSG00000025857(Heatr2) ENSG00000164818(HEATR2) "viable,visible" trichogen cell FBgn0032691 Atac2 Ada2a-containing complex component 2 http://flybase.net/reports/FBgn0032691.html protein_coding_gene "0043998=H2A histone acetyltransferase activity, 0008270=zinc ion binding, 0010485=H4 histone acetyltransferase activity" "0006338=chromatin remodeling, 0036335=intestinal stem cell homeostasis, 0043968=histone H2A acetylation, 0016573=histone acetylation, 0043967=histone H4 acetylation, 2000620=positive regulation of histone H4-K16 acetylation" 0005671=Ada2/Gcn5/Ada3 transcription activator complex "ATAC complex component 2, dATAC2, Atac2, KAT14, CG10414, lysine acetyltransferase 14" "IPR001965=Zinc finger, PHD-type, IPR000182=GNAT domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR016181=Acyl-CoA N-acyltransferase, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site" CG10414 16-Dec-15 2015_12 ENSDARG00000041708(csrp2bp) ENSMUSG00000027425(Csrp2bp) ENSG00000149474(CSRP2BP) "viable,fertile,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,somatic clone" "intestinal stem cell,somatic clone,supernumerary" FBgn0052267 CG32267 http://flybase.net/reports/FBgn0052267.html protein_coding_gene CG32267 16-Dec-15 2015_12 "viable,fertile" FBgn0065051 scaRNA:MeU5-U42 small Cajal body-specific RNA : MeU5-U42 http://flybase.net/reports/FBgn0065051.html FBgn0053716 snoRNA_gene 0030555=RNA modification guide activity "0015030=Cajal body, 0005730=nucleolus" "snoR755, snoRNA:755, snoRNA:MeU5-U42, CR33716, MeU5-U42(SnoR755), Dm-755, mgU5-42" CR33716 16-Dec-15 2015_12 FBgn0003957 ups upright scutellars http://flybase.net/reports/FBgn0003957.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,reduced,male sterile" "eye,wing,posterior scutellar bristle" FBgn0037021 CG11399 http://flybase.net/reports/FBgn0037021.html protein_coding_gene 0048190=wing disc dorsal/ventral pattern formation "IPR022035=Phosphorylated CTD interacting factor 1, WW domain, IPR001202=WW domain" CG11399 16-Dec-15 2015_12 ENSDARG00000004917 ENSXETG00000014866(TEgg003n14.1) ENSMUSG00000039849(Pcif1) ENSG00000100982(PCIF1) "viable,fertile,visible" "wing vein,ectopic,embryonic/larval hemocyte | third instar larval stage,macrochaeta" FBgn0266598 Kmn2 kinetochore Mis12-Ndc80 network component 2 http://flybase.net/reports/FBgn0266598.html "FBgn0087022, FBgn0260723" protein_coding_gene "0031262=Ndc80 complex, 0000776=kinetochore" "CG42550, HDC12388" CG42550 16-Dec-15 2015_12 FBgn0250836 CG8628 http://flybase.net/reports/FBgn0250836.html "FBgn0035744, FBgn0066925" protein_coding_gene "0004857=enzyme inhibitor activity, 0000062=fatty-acyl-CoA binding, 0050809=diazepam binding" 0042049=cellular acyl-CoA homeostasis anon-SAGE:Wang-073 "IPR000582=Acyl-CoA-binding protein, ACBP, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR022408=Acyl-CoA-binding protein, ACBP, conserved site" CG8628 16-Dec-15 2015_12 FBgn0266206 CR44901 http://flybase.net/reports/FBgn0266206.html non_protein_coding_gene CR44901 16-Dec-15 2015_12 FBgn0085488 CG34459 http://flybase.net/reports/FBgn0085488.html "FBan0006301, FBgn0034161" protein_coding_gene CG6301 IPR007999=Protein of unknown function DUF745 CG34459 16-Dec-15 2015_12 viable FBgn0037162 CG11449 http://flybase.net/reports/FBgn0037162.html protein_coding_gene CG11449 16-Dec-15 2015_12 "ENSDARG00000068103(zgc:158569),ENSDARG00000055406" ENSXETG00000008111(Q6P2Y6_XENTR) ENSMUSG00000026546(Ccdc19) ENSG00000213085(CCDC19) viable DRSC11662 E 0.317413761 1.135001344 -1.551967676 0.94914908 0.45962852 0.739851471 FBgn0031248 CG11912 http://flybase.net/reports/FBgn0031248.html FBgn0044771 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP140, anon-WO0140519.112" "IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan" CG11912 16-Dec-15 2015_12 viable FBgn0065543 l(2)SH1056 lethal (2) SH1056 http://flybase.net/reports/FBgn0065543.html gene l(2)SH2 1056 16-Dec-15 2015_12 "lethal,recessive" FBgn0054050 CG34050 http://flybase.net/reports/FBgn0054050.html FBgn0082655 protein_coding_gene "BP1085, unnamed, mdcds_24470, HDC09511" 16-Dec-15 2015_12 DRSC09067 IK -0.596218742 -2.4328824 -0.25498206 -1.423359296 0.963259994 2.818725041 FBgn0017389 l(1)15Db lethal (1) 15Db http://flybase.net/reports/FBgn0017389.html gene 16-Dec-15 2015_12 lethal FBgn0024716 anon-26Ab anon-26Ab http://flybase.net/reports/FBgn0024716.html gene 16-Dec-15 2015_12 FBgn0031085 CG9570 http://flybase.net/reports/FBgn0031085.html protein_coding_gene CG9570 16-Dec-15 2015_12 viable FBgn0067779 dbr debra http://flybase.net/reports/FBgn0067779.html "FBgn0028472, FBgn0043386" protein_coding_gene 0008270=zinc ion binding 0007616=long-term memory "0005771=multivesicular body, 0005634=nucleus" "CG11371, EP456, BcDNA:LD26519, Debra, EP0456, Dbr" "IPR012934=Zinc finger, AD-type" CG11371 16-Dec-15 2015_12 "memory defective,RU486 conditional,visible,lethal,viable" "wing vein L3,somatic clone,wing vein L4,ectopic,crossvein,macrochaeta,tormogen cell,trichogen cell,eye,external sensory organ,micropyle,drug conditional,dorsal appendage" FBgn0250819 CG33521 http://flybase.net/reports/FBgn0250819.html "FBgn0053521, FBgn0022341, FBgn0025215, FBgn0025232, FBgn0052015, FBtr0089197, FBpp0088261, FBtr0089198, FBpp0088262, FBtr0089199, FBpp0088263, FBtr0089200, FBpp0088264, FBgn0062975" protein_coding_gene 0008270=zinc ion binding "anon2D9, CG17467, anon-fast-evolving-2A9, unnamed, anon-fast-evolving-2E7, anon-EST:fe2A9, anon-fast-evolving-2D9, anon-EST:fe2E7, CG32015, BcDNA:RE73965, anon-EST:fe2D9, 2D9" "IPR001781=Zinc finger, LIM-type" CG33521 16-Dec-15 2015_12 WBGene00013289(tag-273) ENSG00000050405(LIMA1) FBgn0036939 CG7365 http://flybase.net/reports/FBgn0036939.html protein_coding_gene 0004620=phospholipase activity 0006909=phagocytosis "IPR001087=GDSL lipase/esterase, IPR013830=SGNH hydrolase-type esterase domain" CG7365 16-Dec-15 2015_12 "WBGene00008621(F09C8.1),WBGene00022256(Y73B6BL.37),WBGene00022040(Y65B4BR.1),WBGene00012201(W02B12.1)" ENSXETG00000012248(PLB1) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0267601 CR45939 http://flybase.net/reports/FBgn0267601.html non_protein_coding_gene CR45939 16-Dec-15 2015_12 FBgn0013609 l(3)E7-3-58 lethal (3) E7-3-58 http://flybase.net/reports/FBgn0013609.html gene 16-Dec-15 2015_12 lethal FBgn0041599 l(2)IIa lethal (2) IIa http://flybase.net/reports/FBgn0041599.html gene unnamed 16-Dec-15 2015_12 FBgn0032311 CG12517 http://flybase.net/reports/FBgn0032311.html protein_coding_gene 0005125=cytokine activity "0007165=signal transduction, 0007304=chorion-containing eggshell formation" 0042600=chorion CG12517 16-Dec-15 2015_12 FBgn0032966 CG1421 http://flybase.net/reports/FBgn0032966.html FBgn0063085 protein_coding_gene BcDNA:LP11549 IPR007846=RNA-recognition motif (RRM) Nup35-type domain CG1421 16-Dec-15 2015_12 viable FBgn0029514 312 312 http://flybase.net/reports/FBgn0029514.html "FBgn0035214, FBgn0046312" protein_coding_gene "BEST:CK01660, CG9166" "IPR004394=Protein Iojap/ribosomal silencing factor RsfS, IPR025656=Oligomerisation domain" CG9166 16-Dec-15 2015_12 viable FBgn0058121 CG40121 http://flybase.net/reports/FBgn0058121.html FBan0040121 protein_coding_gene 16-Dec-15 2015_12 FBgn0065427 l(2)SH1513 lethal (2) SH1513 http://flybase.net/reports/FBgn0065427.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034126 CG4398 http://flybase.net/reports/FBgn0034126.html protein_coding_gene IPR010629=Insect allergen-related CG4398 16-Dec-15 2015_12 viable FBgn0041614 TAS Telomeric Associated Sequences http://flybase.net/reports/FBgn0041614.html repeat_region telomere-associated sequence 16-Dec-15 2015_12 FBgn0038564 CG7785 http://flybase.net/reports/FBgn0038564.html protein_coding_gene CLLD6 "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR003877=SPRY domain" CG7785 16-Dec-15 2015_12 "ENSDARG00000012543,ENSDARG00000069485(zgc:66415),ENSDARG00000052624(si:dkey-7a20.6)" WBGene00008939(F18H3.1) ENSXETG00000015683(TEgg078f12.1) ENSMUSG00000021930(6330409N04Rik) ENSG00000123178(SPRYD7) "viable,fertile" FBgn0001716 l(1)ESHS37 lethal (1) ESHS37 http://flybase.net/reports/FBgn0001716.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262144 CG42870 http://flybase.net/reports/FBgn0262144.html protein_coding_gene lincRNA.828 CG42870 16-Dec-15 2015_12 FBgn0263336 CR43417 http://flybase.net/reports/FBgn0263336.html non_protein_coding_gene CR43417 16-Dec-15 2015_12 FBgn0000916 fs(1)ne2 female sterile (1) no eggs 2 http://flybase.net/reports/FBgn0000916.html gene "fs(1)ne[2], ne2" 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0028651 anon-55Ea anon-55Ea http://flybase.net/reports/FBgn0028651.html gene A-2300 16-Dec-15 2015_12 FBgn0017387 l(1)15Dd lethal (1) 15Dd http://flybase.net/reports/FBgn0017387.html gene 16-Dec-15 2015_12 lethal FBgn0000372 cripA crippled A http://flybase.net/reports/FBgn0000372.html gene 0007629=flight behavior crpA 16-Dec-15 2015_12 "hypoactive,uncoordinated" FBgn0035070 CG3650 http://flybase.net/reports/FBgn0035070.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP159 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG3650 16-Dec-15 2015_12 pupal stage salivary gland

viable FBgn0082936 snoRNA:Me28S-C2645c http://flybase.net/reports/FBgn0082936.html snoRNA_gene "CR34589, DmSnR64c, Me28S-Cm2645c, snoRNA:Me28S-Cm2645c" CR34589 16-Dec-15 2015_12 FBgn0052728 CR32728 http://flybase.net/reports/FBgn0052728.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0019847 anon-XVIII anon-XVIII http://flybase.net/reports/FBgn0019847.html gene XVIII 16-Dec-15 2015_12 FBgn0013594 l(3)A519.1F3 lethal (3) A519.1F3 http://flybase.net/reports/FBgn0013594.html gene 16-Dec-15 2015_12 lethal FBgn0069244 daltonian daltonian http://flybase.net/reports/FBgn0069244.html gene 0001754=eye photoreceptor cell differentiation 16-Dec-15 2015_12 FBgn0086021 snoRNA:MeU6-C68 http://flybase.net/reports/FBgn0086021.html snoRNA_gene "MeU6-C68, mgU6-68, MeU6-Cm68, CR34650" CR34650 16-Dec-15 2015_12 FBgn0069079 stoc stocherkahn http://flybase.net/reports/FBgn0069079.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal,germline clone,non-rescuable maternal effect" "dorsal closure embryo,germline clone,non-rescuable maternal effect,maternal effect" FBgn0019985 mGluR metabotropic Glutamate Receptor http://flybase.net/reports/FBgn0019985.html protein_coding_gene "0001641=group II metabotropic glutamate receptor activity, 0015485=cholesterol binding, 0004930=G-protein coupled receptor activity, 0016595=glutamate binding, 0008066=glutamate receptor activity" "0007216=G-protein coupled glutamate receptor signaling pathway, 0051966=regulation of synaptic transmission, glutamatergic, 0072553=terminal button organization, 0007528=neuromuscular junction development" "0038038=G-protein coupled receptor homodimeric complex, 0045121=membrane raft, 0005887=integral component of plasma membrane, 0005886=plasma membrane, 0016021=integral component of membrane" "CG11144, DmGluR[[A]], mGLuR, Metabotropic glutamate receptor, DmGluAR, DmGlu[[A]]R, CAA67993.1_Dr, DmGlu-RA, Metabotropic Glutamate Receptor, Glu-RA, DmGlu-A, mGluR, dmGluRA, metabotropic glutamate receptor, DmGluRA, DmGluR, mGluRA, DmGluA, GluR" "IPR001828=Receptor, ligand binding region, IPR017978=GPCR, family 3, C-terminal, IPR017979=GPCR, family 3, conserved site, IPR011500=GPCR, family 3, nine cysteines domain, IPR028082=Periplasmic binding protein-like I, IPR000162=GPCR, family 3, metabotropic glutamate receptor, IPR000337=GPCR, family 3" CG11144 16-Dec-15 2015_12 "ENSDARG00000031712(LOC565256),ENSDARG00000004150(wu:fj52c07),ENSDARG00000007195" WBGene00003232(mgl-1) ENSXETG00000005426(GRM3) ENSMUSG00000003974(Grm3) "ENSG00000198822(GRM3),ENSG00000164082(GRM2)" "viable,neurophysiology defective,neuroanatomy defective,recessive" "type I bouton,bouton,supernumerary" FBgn0039483 CG14259 http://flybase.net/reports/FBgn0039483.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG14259 16-Dec-15 2015_12 viable FBgn0265704 CR44511 http://flybase.net/reports/FBgn0265704.html non_protein_coding_gene lincRNA.396 CR44511 16-Dec-15 2015_12 FBgn0265102 Oseg1 Outer segment 1 http://flybase.net/reports/FBgn0265102.html "FBgn0043879, FBgn0035891" protein_coding_gene "0050954=sensory perception of mechanical stimulus, 0042384=cilium assembly, 0035058=nonmotile primary cilium assembly, 0035721=intraciliary retrograde transport" "0031513=nonmotile primary cilium, 0030991=intraciliary transport particle A" "OSM-4, DAF-10, mecC, CG7161, OSEG1, Wdr10, oseg1, OSEG, Oseg1, mechanosensory C, IFT122" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG7161 16-Dec-15 2015_12 ENSDARG00000067587 WBGene00000906(daf-10) ENSXETG00000001463() ENSMUSG00000030323(Ift122) ENSG00000163913(IFT122) FBgn0065416 l(2)SH1541 lethal (2) SH1541 http://flybase.net/reports/FBgn0065416.html gene l(2)SH2 1541 16-Dec-15 2015_12 "lethal,recessive" FBgn0266203 CR44898 http://flybase.net/reports/FBgn0266203.html non_protein_coding_gene CR44898 16-Dec-15 2015_12 FBgn0035016 CG4612 http://flybase.net/reports/FBgn0035016.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0008143=poly(A) binding" cg4612 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG4612 16-Dec-15 2015_12 visible wing FBgn0005146 l(2)DTS9 lethal (2) DTS9 http://flybase.net/reports/FBgn0005146.html gene DTS-L9 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive" FBgn0020844 l(2)21Ba1 lethal (2) 21Ba1 http://flybase.net/reports/FBgn0020844.html gene 21Ba1 16-Dec-15 2015_12 FBgn0065940 l(2)SH0116 lethal (2) SH0116 http://flybase.net/reports/FBgn0065940.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083075 ms(3)236 ms(3)236 http://flybase.net/reports/FBgn0083075.html gene 16-Dec-15 2015_12 FBgn0042147 CG18824 http://flybase.net/reports/FBgn0042147.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027609 morgue "modifier of rpr and grim, ubiquitously expressed" http://flybase.net/reports/FBgn0027609.html protein_coding_gene "0036435=K48-linked polyubiquitin binding, 0004842=ubiquitin-protein transferase activity" "0006915=apoptotic process, 1901694=positive regulation of compound eye retinal cell apoptotic process, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0046668=regulation of retinal cell programmed cell death, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "CG15437, Morgue, FBXO18, morgue, BcDNA:GH02435" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR001810=F-box domain" CG15437 16-Dec-15 2015_12 " embryonic stage -- adult stage , pupal stage--adult stage , pupal stage " " organism

, primary pigment cell

, tertiary pigment cell

, secondary pigment cell

" "viable,hypoactive,visible,decreased cell death,recessive,partially lethal - majority die,melanotic mass phenotype,lethal,some die during third instar larval stage,some die during pupal stage,partially lethal" "anterior pupal spiracle,tergite,midline glial cell,supernumerary,pigment cell,chaeta,leg,melanotic mass,embryonic peripheral glial cell 10,support cell of the dorsal bipolar dendritic cell" DRSC00264 I 0.578050001 -1.543783132 0.284723587 0.115384271 -0.532947828 -0.51377844 FBgn0046709 GIIIC GIIIC http://flybase.net/reports/FBgn0046709.html gene 0004623=phospholipase A2 activity 0005576=extracellular region dGIIIC 16-Dec-15 2015_12 FBgn0023507 CG3835 http://flybase.net/reports/FBgn0023507.html protein_coding_gene "0008762=UDP-N-acetylmuramate dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" 0055114=oxidation-reduction process "EG87B1, EG:87B1.3" "IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR004113=FAD-linked oxidase, C-terminal, IPR016167=FAD-binding, type 2, subdomain 1, IPR016171=Vanillyl-alcohol oxidase, C-terminal subdomain 2, IPR016164=FAD-linked oxidase-like, C-terminal, IPR006094=FAD linked oxidase, N-terminal, IPR016166=FAD-binding, type 2" CG3835 16-Dec-15 2015_12 ENSDARG00000060210(d2hgdh) "YDL178W(DLD2),YEL071W(DLD3)" WBGene00010055(F54D5.12) ENSMUSG00000073609(D2hgdh) "ENSG00000215692,ENSG00000180902(D2HGDH)" "partially lethal - majority die,some die during pupal stage" FBgn0065710 l(2)SH0598 lethal (2) SH0598 http://flybase.net/reports/FBgn0065710.html gene l(2)SH2 0598 16-Dec-15 2015_12 "lethal,recessive" FBgn0035791 CG8539 http://flybase.net/reports/FBgn0035791.html protein_coding_gene "0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" 0006508=proteolysis "IPR000834=Peptidase M14, carboxypeptidase A" CG8539 16-Dec-15 2015_12 FBgn0061482 rover\pol pol http://flybase.net/reports/FBgn0061482.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0069086 sah sahnehaeubchen http://flybase.net/reports/FBgn0069086.html gene 0007310=oocyte dorsal/ventral axis specification 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" chorion | germline clone | maternal effect FBgn0001057 Fs(3)Kev Female sterile (3) Keve http://flybase.net/reports/FBgn0001057.html gene "Fs(3)Sz16, Fs(3)Keve" 16-Dec-15 2015_12 "visible,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0266943 CR45394 http://flybase.net/reports/FBgn0266943.html non_protein_coding_gene CR45394 16-Dec-15 2015_12 FBgn0260770 CG42568 http://flybase.net/reports/FBgn0260770.html "FBgn0034983, FBgn0020129" protein_coding_gene "CG12240, CG13571" CG42568 16-Dec-15 2015_12 FBgn0062696 EP1191 EP1191 http://flybase.net/reports/FBgn0062696.html gene EP(3)1191 16-Dec-15 2015_12 FBgn0031857 CG11321 http://flybase.net/reports/FBgn0031857.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination 0071797=LUBAC complex AAF52435.2 "IPR002867=IBR domain, IPR001841=Zinc finger, RING-type, IPR026254=E3 ubiquitin-protein ligase RNF31, IPR001876=Zinc finger, RanBP2-type" CG11321 16-Dec-15 2015_12 ENSG00000092098(RNF31) viable FBgn0266707 CR45197 http://flybase.net/reports/FBgn0266707.html non_protein_coding_gene CR45197 16-Dec-15 2015_12 FBgn0266213 CR44908 http://flybase.net/reports/FBgn0266213.html non_protein_coding_gene CR44908 16-Dec-15 2015_12 FBgn0085495 CG40534 http://flybase.net/reports/FBgn0085495.html FBan0040534 protein_coding_gene 16-Dec-15 2015_12 FBgn0004772 l(3)91Ca lethal (3) 91Ca http://flybase.net/reports/FBgn0004772.html gene l(3)CR1 16-Dec-15 2015_12 lethal FBgn0030088 Arfrp1 ADP-ribosylation factor related protein 1 http://flybase.net/reports/FBgn0030088.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" 0007264=small GTPase mediated signal transduction 0005622=intracellular "ARFRP1, Q9W389, Arp1, CG7039" "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR024156=Small GTPase superfamily, ARF type" CG7039 16-Dec-15 2015_12 ENSDARG00000057857 YPL051W(ARL3) WBGene00021841(Y54E10BR.2) ENSMUSG00000038671(Arfrp1) ENSG00000101246(ARFRP1) "lethal,viable,visible" "embryonic/larval brain,trichogen cell" DRSC18417 K -0.099003464 -0.10536053 -0.472733818 -1.35336419 0.352440365 1.628296447 FBgn0265745 CR44552 http://flybase.net/reports/FBgn0265745.html non_protein_coding_gene CR44552 16-Dec-15 2015_12 FBgn0024862 l(3)09402 lethal (3) 09402 http://flybase.net/reports/FBgn0024862.html gene 9402 16-Dec-15 2015_12 "lethal,recessive" FBgn0051308 CG31308 http://flybase.net/reports/FBgn0051308.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025839 ND-B14.5A NADH dehydrogenase (ubiquinone) B14.5 A subunit http://flybase.net/reports/FBgn0025839.html "FBgn0014087, FBgn0047059" protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "RNAA, N4AM, NADH:ubiquinone oxidoreductase B14.5A subunit, NADH ubiquinone oxidoreductase B14.5A, BcDNA:RE75088, EG:152A3.7, FBpp0070370, 152A3.7, NADH-ubiquinone oxidoreductase subunit B14.5a, CG3621, anon-2Db, anon-2D" IPR009947=NADH:ubiquinone oxidoreductase subunit B14.5a CG3621 16-Dec-15 2015_12 ENSDARG00000036684(zgc:92850) ENSMUSG00000041881(Ndufa7) ENSG00000167774(NDUFA7) FBgn0035077 CG9083 http://flybase.net/reports/FBgn0035077.html protein_coding_gene CG9083 16-Dec-15 2015_12 FBgn0040247 anon-57Ba anon-57Ba http://flybase.net/reports/FBgn0040247.html gene 16-Dec-15 2015_12 FBgn0263443 CR43466 http://flybase.net/reports/FBgn0263443.html non_protein_coding_gene CR43466 16-Dec-15 2015_12 FBgn0267046 CG45490 http://flybase.net/reports/FBgn0267046.html protein_coding_gene CG45490 16-Dec-15 2015_12 FBgn0001527 l(1)11Ec lethal (1) 11Ec http://flybase.net/reports/FBgn0001527.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0050274 CG30274 http://flybase.net/reports/FBgn0050274.html FBgn0034780 protein_coding_gene 0016301=kinase activity CG13529 "IPR022414=ATP:guanido phosphotransferase, catalytic domain, IPR022413=ATP:guanido phosphotransferase, N-terminal, IPR014746=Glutamine synthetase/guanido kinase, catalytic domain, IPR000749=ATP:guanido phosphotransferase" CG30274 16-Dec-15 2015_12 viable FBgn0010123 l(1)EN7 lethal (1) from Eugene Nonautonomous 7 http://flybase.net/reports/FBgn0010123.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" fat body FBgn0015913 big bendless interacting gene product http://flybase.net/reports/FBgn0015913.html gene 16-Dec-15 2015_12 FBgn0028844 CG15283 http://flybase.net/reports/FBgn0028844.html FBgn0040980 protein_coding_gene 0090175=regulation of establishment of planar polarity "BG:DS08340.1, DS08340.1" IPR012875=Protein of unknown function DUF1674 CG15283 16-Dec-15 2015_12 "viable,planar polarity defective" "wing hair,ommatidium" FBgn0039101 CG16710 http://flybase.net/reports/FBgn0039101.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP16 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG16710 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0040322 GNBP2 Gram-negative bacteria binding protein 2 http://flybase.net/reports/FBgn0040322.html FBgn0036802 protein_coding_gene "0052736=beta-glucanase activity, 0001872=(1->3)-beta-D-glucan binding, 0008329=signaling pattern recognition receptor activity, 0001530=lipopolysaccharide binding" "0002758=innate immune response-activating signal transduction, 0005975=carbohydrate metabolic process, 0045088=regulation of innate immune response" "0000502=proteasome complex, 0005576=extracellular region" "gnbp2, CG4144, DGNBP-2, GNBP" "IPR000757=Glycoside hydrolase, family 16, IPR013320=Concanavalin A-like lectin/glucanase domain" CG4144 16-Dec-15 2015_12 viable FBgn0063904 Neurodegeneration-7 Neurodegeneration 7 http://flybase.net/reports/FBgn0063904.html gene "ND7, ND8" 16-Dec-15 2015_12 "paralytic,dominant" "central nervous system,brain" FBgn0053245 Ste:CG33245 Ste:CG33245 http://flybase.net/reports/FBgn0053245.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33245" "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet" CG33245 16-Dec-15 2015_12 FBgn0000840 fs(1)M27 female sterile (1) M27 http://flybase.net/reports/FBgn0000840.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0260025 fonseca fonseca http://flybase.net/reports/FBgn0260025.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0028889 tRNA:L:35C tRNA:L:35C http://flybase.net/reports/FBgn0028889.html "FBgn0051831, FBgn0060153" tRNA_gene 0033403=UUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA[Leu], CR31831, tRNA:L:TAA:AE002690, AE002690.trna13-LeuTAA, tRNA:leu, DtL[b], BG:DS03192.1, tRNA[LEU], chr2L.trna22-LeuTAA" CR31831 16-Dec-15 2015_12 FBgn0000144 Attenuated Attenuated http://flybase.net/reports/FBgn0000144.html gene At 16-Dec-15 2015_12 "viable,male fertile,female fertile,visible,dominant,good,fertile" wing FBgn0040230 dbo diablo http://flybase.net/reports/FBgn0040230.html FBgn0036535 protein_coding_gene 0003779=actin binding "0048812=neuron projection morphogenesis, 0016049=cell growth, 0050807=regulation of synapse organization" "Smac, Dbo, DIABLO, Dm.DBO, CG6224" "IPR011333=POZ domain, IPR011043=Galactose oxidase/kelch, beta-propeller, IPR000210=BTB/POZ domain, IPR015916=Galactose oxidase, beta-propeller, IPR017096=BTB-kelch protein, IPR011705=BTB/Kelch-associated, IPR006652=Kelch repeat type 1" CG6224 16-Dec-15 2015_12 ENSDARG00000038801(klhl20) WBGene00020030(R12E2.1) ENSXETG00000000516(KLHL20) ENSMUSG00000026705(Klhl20) ENSG00000076321(KLHL20) "planar polarity defective,viable,fertile" wing hair FBgn0035976 PGRP-LC Peptidoglycan recognition protein LC http://flybase.net/reports/FBgn0035976.html FBgn0046840 protein_coding_gene "0015640=peptidoglycan peptide transporter activity, 0001875=lipopolysaccharide receptor activity, 0005515=protein binding, 0008270=zinc ion binding, 0046983=protein dimerization activity, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0042834=peptidoglycan binding, 0016019=peptidoglycan receptor activity, 0008329=signaling pattern recognition receptor activity" "0019731=antibacterial humoral response, 0016045=detection of bacterium, 0019730=antimicrobial humoral response, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0009617=response to bacterium, 0009253=peptidoglycan catabolic process, 0006952=defense response, 0051607=defense response to virus, 0045087=innate immune response, 0002920=regulation of humoral immune response, 0006955=immune response, 0061057=peptidoglycan recognition protein signaling pathway, 0035007=regulation of melanization defense response, 0006909=phagocytosis, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0050829=defense response to Gram-negative bacterium" "0044214=spanning component of plasma membrane, 0005737=cytoplasm, 0005887=integral component of plasma membrane, 0016327=apicolateral plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "ird7, (PGRP)-LC, Peptidoglycan-recognition protein-LC, totem, PGRP-LCx, PGRP-LCa, tot, CG4432, PGRP-LC, Dm PGRP-LC, Pgrp-LC, immune response deficient 7, peptidoglycan recognition protein-LC, pgrp-lc, PGRPLC" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR015510=Peptidoglycan recognition protein, IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR019787=Zinc finger, PHD-finger, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR001965=Zinc finger, PHD-type" CG4432 16-Dec-15 2015_12 "immune response defective,visible,short lived,conditional,viable,recessive,fertile,lethal,melanotic mass phenotype" wing FBgn0084374 E-3a Enhancer on chromosome 3-complementation group a http://flybase.net/reports/FBgn0084374.html gene 16-Dec-15 2015_12 visible "wing,haltere" FBgn0039094 CG10184 http://flybase.net/reports/FBgn0039094.html protein_coding_gene 0004793=threonine aldolase activity 0006520=cellular amino acid metabolic process "IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR001597=Aromatic amino acid beta-eliminating lyase/threonine aldolase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR023603=Threonine aldolase, IPR015424=Pyridoxal phosphate-dependent transferase" CG10184 16-Dec-15 2015_12 ENSDARG00000008547 YEL046C(GLY1) WBGene00011291(R102.4) ENSXETG00000009985(Q5BKH8_XENTR) ENSMUSG00000017713(Tha1) viable FBgn0036449 bmm brummer http://flybase.net/reports/FBgn0036449.html protein_coding_gene 0004806=triglyceride lipase activity "0016042=lipid catabolic process, 0006629=lipid metabolic process, 0055088=lipid homeostasis, 0019433=triglyceride catabolic process, 0010884=positive regulation of lipid storage, 0008340=determination of adult lifespan, 0006642=triglyceride mobilization" "0005829=cytosol, 0005811=lipid particle" "Atgl, CG5295, Bmm, adipocyte triglyceride lipase, Brummer, brummer lipase, ATGL" "IPR002641=Patatin/Phospholipase A2-related, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase" CG5295 16-Dec-15 2015_12 WBGene00015484(C05D11.7) "ENSXETG00000004865(Q5FWR9_XENTR),ENSXETG00000019027(PNPLA2)" "ENSMUSG00000025509(Pnpla2),ENSMUSG00000041653(Pnpla3)" "ENSG00000177666(PNPLA2),ENSG00000100344(PNPLA3),ENSG00000100341(PNPLA5)" "viable,short lived,recessive,long lived,stress response defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,visible" "adult fat body,embryonic/larval midgut,lipid droplet & larval oenocyteppl.PP,lipid droplet & larval oenocyteLsp2.PH,chaeta,supernumerary" FBgn0082686 E(ftz)20 E(ftz)20 http://flybase.net/reports/FBgn0082686.html gene 20 16-Dec-15 2015_12 FBgn0005414 l(1)adl3 lethal (1) adl3 http://flybase.net/reports/FBgn0005414.html gene l(1)adl-3 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile,short lived,gravitaxis defective,phototaxis defective,behavior defective" FBgn0039069 CG6763 http://flybase.net/reports/FBgn0039069.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" 0006508=proteolysis 0017090=meprin A complex "IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR001506=Peptidase M12A, astacin" CG6763 16-Dec-15 2015_12 "ENSDARG00000019122(he1b),ENSDARG00000023656(he1a),ENSDARG00000022670(he2),ENSDARG00000058409,ENSDARG00000010423(npsn),ENSDARG00000024503(c6ast3),ENSDARG00000052578(c6ast4),ENSDARG00000070011(LOC100003133),ENSDARG00000069216(c6ast1)" "WBGene00003523(nas-4),WBGene00003532(nas-13)" ENSXETG00000015923() ENSMUSG00000050468(Astl) ENSG00000188886(ASTL) viable FBgn0019726 l(2)46CFb lethal (2) 46CFb http://flybase.net/reports/FBgn0019726.html gene "1.11, unnamed" 16-Dec-15 2015_12 FBgn0029022 l(3)77ABj lethal (3) 77ABj http://flybase.net/reports/FBgn0029022.html gene unnamed 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0062678 EP2087 EP2087 http://flybase.net/reports/FBgn0062678.html gene EP(2)2087 16-Dec-15 2015_12 FBgn0053145 GalT1 "ë_1,3-galactosyltransferase 1" http://flybase.net/reports/FBgn0053145.html FBgn0033671 protein_coding_gene "0048531=beta-1,3-galactosyltransferase activity, 0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" 0006487=protein N-linked glycosylation 0016020=membrane "dbeta3GnT, CG33145, CG8976" "IPR002659=Glycosyl transferase, family 31" CG33145 16-Dec-15 2015_12 "ENSDARG00000018971(b3gnt5),ENSDARG00000004396(zgc:101733)" WBGene00019539 "ENSXETG00000016205(B3GALT1),ENSXETG00000004532(B3GALT2),ENSXETG00000004536(BC075347.1),ENSXETG00000002261(),ENSXETG00000011652(),ENSXETG00000006113(),ENSXETG00000006114(),ENSXETG00000006118(),ENSXETG00000006123(),ENSXETG00000002237(B3GNT1)" "viable,fertile" FBgn0046670 anon-38C.25 anon-38C.25 http://flybase.net/reports/FBgn0046670.html gene 38C.25 16-Dec-15 2015_12 FBgn0004014 wi witty eye http://flybase.net/reports/FBgn0004014.html gene 16-Dec-15 2015_12 "eye,ommatidium,vibrissae" FBgn0083979 Ir10a Ionotropic receptor 10a http://flybase.net/reports/FBgn0083979.html "FBan0012624, FBgn0030284, FBgn0030285" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 10a, CG12623, DmelIR10a, CG12624, IR10a, CG34143" CG34143 16-Dec-15 2015_12 viable FBgn0030486 Set2 SET domain containing 2 http://flybase.net/reports/FBgn0030486.html protein_coding_gene "0008134=transcription factor binding, 0003712=transcription cofactor activity, 0051219=phosphoprotein binding, 0046975=histone methyltransferase activity (H3-K36 specific), 0003677=DNA binding, 0018024=histone-lysine N-methyltransferase activity" "0002168=instar larval development, 0035220=wing disc development, 0006355=regulation of transcription, DNA-templated, 0016571=histone methylation, 0035076=ecdysone receptor-mediated signaling pathway, 0010452=histone H3-K36 methylation" "0005694=chromosome, 0005634=nucleus" "CG1716, Drosophila Hypb, dSet2, dHypb, Set2, Hypb, SET2, set2" "IPR001202=WW domain, IPR001214=SET domain, IPR017956=AT hook, DNA-binding motif, IPR013257=SRI, Set2 Rpb1 interacting, IPR000742=EGF-like domain, IPR003616=Post-SET domain, IPR006560=AWS domain" CG1716 16-Dec-15 2015_12 WBGene00016603(met-1) ENSMUSG00000044791(Setd2) ENSG00000181555(SETD2) "visible,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,viable,recessive,somatic clone" "wing,eye,somatic clone" FBgn0052462 CG32462 http://flybase.net/reports/FBgn0052462.html FBgn0037196 protein_coding_gene CG8220 CG32462 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0036207 CG10907 http://flybase.net/reports/FBgn0036207.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG10907 16-Dec-15 2015_12 ENSDARG00000043727(zgc:56702) WBGene00000892(cyn-16) ENSXETG00000000459(SDCCAG10) ENSMUSG00000021715(Cwc27) ENSG00000153015(CWC27) viable FBgn0054038 CG34038 http://flybase.net/reports/FBgn0054038.html FBgn0082883 protein_coding_gene "BP1023, Dm_2R:93799, Dm_2R:93795, unnamed" CG34038 16-Dec-15 2015_12 FBgn0019984 Gp14B Glycoprotein 14B http://flybase.net/reports/FBgn0019984.html gene gp 16-Dec-15 2015_12 FBgn0262458 mir-305 mir-305 stem loop http://flybase.net/reports/FBgn0262458.html "FBgn0067700, FBgn0262325" miRNA_gene "0036335=intestinal stem cell homeostasis, 0046626=regulation of insulin receptor signaling pathway, 0042594=response to starvation, 0008593=regulation of Notch signaling pathway, 0031670=cellular response to nutrient" "miR305, MiR-305, dme-miR-305, CR43032, miR-305, mir-305, miR 305, CR33608, dme-mir-305, 305, mir305" CR43032 16-Dec-15 2015_12 "visible,lethal" wing FBgn0000423 ddl displaced-like http://flybase.net/reports/FBgn0000423.html gene dd[3] 16-Dec-15 2015_12 "visible,viable,reduced,male sterile,male,poor" "adult head,eye,macrochaeta & adult thorax,wing" FBgn0035157 CG13894 http://flybase.net/reports/FBgn0035157.html protein_coding_gene 0003677=DNA binding dmCG13894 "IPR006612=Zinc finger, C2CH-type, IPR006600=HTH CenpB-type DNA-binding domain, IPR009057=Homeodomain-like" CG13894 16-Dec-15 2015_12 ENSMUSG00000036442(Thap11) viable FBgn0040642 CG12545 http://flybase.net/reports/FBgn0040642.html protein_coding_gene 16-Dec-15 2015_12 FBgn0084765 1577 1577 http://flybase.net/reports/FBgn0084765.html gene 16-Dec-15 2015_12 FBgn0014918 anon-72ABb anon-72ABb http://flybase.net/reports/FBgn0014918.html gene 16-Dec-15 2015_12 FBgn0085267 CG34238 http://flybase.net/reports/FBgn0085267.html protein_coding_gene CG34238 16-Dec-15 2015_12 FBgn0250820 meigo medial glomeruli http://flybase.net/reports/FBgn0250820.html "FBgn0038863, FBgn0025240, FBgn0045415" protein_coding_gene 0005459=UDP-galactose transmembrane transporter activity "0007411=axon guidance, 0006487=protein N-linked glycosylation, 0055085=transmembrane transport, 0070983=dendrite guidance, 0034976=response to endoplasmic reticulum stress" 0005789=endoplasmic reticulum membrane "anon-EST:fe1H6, NEST:bs03h03, unnamed, anon-fast-evolving-1H6, CG5802, Meigo" IPR013657=UAA transporter CG5802 16-Dec-15 2015_12 "ENSDARG00000070689(LOC100330261),ENSDARG00000038213(slc35b1)" YPL244C(HUT1) WBGene00013740(hut-1) ENSXETG00000015126(slc35b1) ENSMUSG00000020873(Slc35b1) ENSG00000121073(SLC35B1) FBgn0037320 CG14668 http://flybase.net/reports/FBgn0037320.html protein_coding_gene CG14668 16-Dec-15 2015_12 viable FBgn0062524 l(3)88EFh lethal (3) 88EFh http://flybase.net/reports/FBgn0062524.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,abdominal 8 ventral denticle belt" FBgn0066366 dru drujok http://flybase.net/reports/FBgn0066366.html gene "0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 memory defective FBgn0065699 l(2)SH0624 lethal (2) SH0624 http://flybase.net/reports/FBgn0065699.html gene l(2)SH2 0624 16-Dec-15 2015_12 "lethal,recessive" FBgn0065649 l(2)SH0735 lethal (2) SH0735 http://flybase.net/reports/FBgn0065649.html gene l(2)SH2 0735 16-Dec-15 2015_12 "lethal,recessive" FBgn0025463 Bap60 Brahma associated protein 60kD http://flybase.net/reports/FBgn0025463.html protein_coding_gene "0008134=transcription factor binding, 0001085=RNA polymerase II transcription factor binding, 0005515=protein binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003713=transcription coactivator activity, 0003677=DNA binding, 0017022=myosin binding" "0048813=dendrite morphogenesis, 0048666=neuron development, 0010628=positive regulation of gene expression, 0031453=positive regulation of heterochromatin assembly, 0006357=regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0045893=positive regulation of transcription, DNA-templated" "0005634=nucleus, 0070604=PBAF complex, 0005719=nuclear euchromatin, 0035060=brahma complex" "BAPp60, BAF60, bap60, Brahma associated protein 60 kD, i133, brahma associated protein 60 kDa, CG4303, i127, BAP60, BRM-associated protein 60" "IPR003121=SWIB/MDM2 domain, IPR019835=SWIB domain" CG4303 16-Dec-15 2015_12 "ENSDARG00000019004(smarcd1),ENSDARG00000038786(smarcd3a),ENSDARG00000019969(smarcd3b)" "YMR233W(TRI1),YOR295W(UAF30)" "WBGene00044072(tag-246),WBGene00015971(C18E3.2)" "ENSXETG00000013357(Smarcd1),ENSXETG00000014415(SMARCD3)" "ENSMUSG00000023018(Smarcd1),ENSMUSG00000028949(Smarcd3)" "ENSG00000066117(SMARCD1),ENSG00000082014(SMARCD3)" "viable,lethal,recessive,germline clone,non-rescuable maternal effect,suppressor of variegation,dominant" embryonic/larval brain FBgn0261262 CG42613 http://flybase.net/reports/FBgn0261262.html "FBgn0051149, FBgn0051222, FBgn0038663, FBgn0038664" protein_coding_gene "CT33918, CG14289, CG31222, CT17110, CG5449, tld-like, CG31149" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000859=CUB domain" CG42613 16-Dec-15 2015_12 WBGene00002977(lev-10) DRSC13332 K -0.608738434 1.4562073 -0.171171736 1.493621161 2.15543771 2.346558651 FBgn0267663 CR46001 http://flybase.net/reports/FBgn0267663.html non_protein_coding_gene CR46001 16-Dec-15 2015_12 FBgn0001957 l(2)28Bc lethal (2) 28Bc http://flybase.net/reports/FBgn0001957.html gene "Complementation group O, O" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001686 l(1)ESHS7 lethal (1) ESHS7 http://flybase.net/reports/FBgn0001686.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0064119 CG33934 http://flybase.net/reports/FBgn0064119.html "FBgn0038770, FBgn0044655, FBgn0052921, FBgn0053934, FBtr0083832, FBtr0083833, FBpp0083242, FBtr0083834" protein_coding_gene 0017153=sodium:dicarboxylate symporter activity "0055085=transmembrane transport, 0006814=sodium ion transport, 0006810=transport" 0016021=integral component of membrane "CG32921-ORFB, CG4961, anon-WO0140519.217, CG32921" IPR001898=Sodium/sulphate symporter CG33934 16-Dec-15 2015_12 "ENSDARG00000039999(LOC100006328),ENSDARG00000053853(slc13a2),ENSDARG00000045638(slc13a1),ENSDARG00000059053(zgc:162495)" "WBGene00003517(nac-1),WBGene00003519(nac-3)" "ENSXETG00000019731(SLC13A5),ENSXETG00000023776(slc13a2),ENSXETG00000008163(slc13a4),ENSXETG00000022751(SLC13A1),ENSXETG00000007850(SLC13A3)" "ENSMUSG00000001095(Slc13a2),ENSMUSG00000020805(Slc13a5),ENSMUSG00000018459(Slc13a3),ENSMUSG00000029700(Slc13a1),ENSMUSG00000029843(Slc13a4)" "ENSG00000007216(SLC13A2),ENSG00000141485(SLC13A5),ENSG00000081800(SLC13A1),ENSG00000158296(SLC13A3),ENSG00000164707(SLC13A4)" FBgn0005712 l(1)TK115 lethal (1) TK115 http://flybase.net/reports/FBgn0005712.html gene l115 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0085710 CG41586 http://flybase.net/reports/FBgn0085710.html FBan0041586 protein_coding_gene 16-Dec-15 2015_12 FBgn0262795 CR43176 http://flybase.net/reports/FBgn0262795.html pseudogene_attribute "CG43176, CG40648" CR43176 16-Dec-15 2015_12 FBgn0000573 elr elliptical rough http://flybase.net/reports/FBgn0000573.html gene 16-Dec-15 2015_12 "visible,viable,fertile" "wing,eye" FBgn0266119 TART-A\RT reverse transcriptase http://flybase.net/reports/FBgn0266119.html transposable_element_gene 16-Dec-15 2015_12 FBgn0086045 snoRNA:Me18S-A627 http://flybase.net/reports/FBgn0086045.html snoRNA_gene "Me18S-Am627, CR34674" CR34674 16-Dec-15 2015_12 FBgn0014284 l(3)64Ac lethal (3) 64Ac http://flybase.net/reports/FBgn0014284.html gene 16-Dec-15 2015_12 FBgn0032538 CG16885 http://flybase.net/reports/FBgn0032538.html FBgn0032537 protein_coding_gene "vajk-2, CG18634" CG16885 16-Dec-15 2015_12 ENSXETG00000000145() DRSC02540 E -0.87157237 0.185291407 1.86025452 -0.635924003 0.454532625 -0.844055447 FBgn0003549 su(B)4 suppressor of Bar on 4 http://flybase.net/reports/FBgn0003549.html gene "m(B)4, modifier of Bar in chromosome 4" 16-Dec-15 2015_12 FBgn0025119 su(RpII140Z36)S9 su(RpII140Z36)S9 http://flybase.net/reports/FBgn0025119.html gene Z36[S9] 16-Dec-15 2015_12 FBgn0260036 33Q1 http://flybase.net/reports/FBgn0260036.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0029970 Nek2 Nek2 http://flybase.net/reports/FBgn0029970.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0005524=ATP binding" "0007088=regulation of mitotic nuclear division, 0006468=protein phosphorylation, 0030177=positive regulation of Wnt signaling pathway, 0007067=mitotic nuclear division, 0031647=regulation of protein stability" "0005813=centrosome, 0030496=midbody" "NEK2, Dm Nek2, CG17256, DmNek2, dNek2" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG17256 16-Dec-15 2015_12 ENSDARG00000005619(nek2) ENSXETG00000025008(NEK2) ENSG00000117650(NEK2) "mitotic cell cycle defective,cytokinesis defective,visible,viable,size defective" "mitotic metaphase & cytoplasm,mitotic anaphase & cytoplasm,mitotic metaphase & spindle,mitotic anaphase & spindle,spindle,centrosome | supernumerary,microtubule,centrosome,mitotic anaphase,mitotic telophase,mitotic telophase & midbody,wing,chaeta,ectopic,centrosomeptc-559.1,wing disc,mesothoracic tergum,scutellum,eye,ommatidium" DRSC18124 K 0.206720188 0.732992709 -0.191069027 0.012796813 1.942243985 -0.117738817 FBgn0052072 Elo68ë± Elongase 68ë± http://flybase.net/reports/FBgn0052072.html "FBgn0036129, FBtr0076232, FBpp0075961" protein_coding_gene 0009922=fatty acid elongase activity "0030497=fatty acid elongation, 0042759=long-chain fatty acid biosynthetic process, 0019368=fatty acid elongation, unsaturated fatty acid, 0042811=pheromone biosynthetic process" 0016021=integral component of membrane "CG32072, elo68alpha, CG6261" IPR002076=ELO family CG32072 16-Dec-15 2015_12 "ENSDARG00000027495(elovl4b),ENSDARG00000006773(elovl4a),ENSDARG00000057365(zgc:112263),ENSDARG00000068551(zgc:153394)" "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" ENSMUSG00000032262(Elovl4) ENSG00000118402(ELOVL4) viable FBgn0002529 Lap-A Leucine aminopeptidase A http://flybase.net/reports/FBgn0002529.html gene "LAP-A, LapA, LAP, leucyl aminopeptidase, Lap, leucine aminopeptidase" 16-Dec-15 2015_12 "electrophoretic variant,slow,fast" FBgn0023139 WppD White prepupal locus D http://flybase.net/reports/FBgn0023139.html gene "13, 4, 20" 16-Dec-15 2015_12 FBgn0060921 l(3)S042412 lethal (3) S042412 http://flybase.net/reports/FBgn0060921.html gene 0424/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0024517 l(3)j1B10 lethal (3) j1B10 http://flybase.net/reports/FBgn0024517.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050484 CG30484 http://flybase.net/reports/FBgn0050484.html FBgn0033877 protein_coding_gene CG13342 CG30484 16-Dec-15 2015_12 viable FBgn0030540 CG11581 http://flybase.net/reports/FBgn0030540.html protein_coding_gene CG11581 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0262452 mir-79 mir-79 stem loop http://flybase.net/reports/FBgn0262452.html "FBgn0067337, FBgn0262312" miRNA_gene "MiR-79, dme-mir-79, miR-79, mir-79, CR33570, 79, CR43019, dme-miR-79-3p" CR43019 16-Dec-15 2015_12 embryonic stage -- adult stage "viable,visible,male,lethal" "wing,male,wing disc" FBgn0260303 GSd483 http://flybase.net/reports/FBgn0260303.html gene 16-Dec-15 2015_12 lethal FBgn0011121 l(1)Q82 lethal (1) Q82 http://flybase.net/reports/FBgn0011121.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0034904 CG15800 http://flybase.net/reports/FBgn0034904.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0006511=ubiquitin-dependent protein catabolic process 0000152=nuclear ubiquitin ligase complex SkpG "IPR011333=POZ domain, IPR016072=SKP1 component, dimerisation, IPR016073=SKP1 component, POZ domain" CG15800 16-Dec-15 2015_12 viable FBgn0035396 CG14953 http://flybase.net/reports/FBgn0035396.html protein_coding_gene 16-Dec-15 2015_12 FBgn0017366 l(3)89Bp lethal (3) 89Bp http://flybase.net/reports/FBgn0017366.html gene l(3)89Bn 16-Dec-15 2015_12 FBgn0026255 clumsy clumsy http://flybase.net/reports/FBgn0026255.html FBgn0032933 protein_coding_gene "0015277=kainate selective glutamate receptor activity, 0005234=extracellular-glutamate-gated ion channel activity" "0006811=ion transport, 0060025=regulation of synaptic activity" 0005886=plasma membrane "GluR39B, Clumsy, CT9037, CG8681, Dmelclumsy" "IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor, IPR001508=Ionotropic glutamate receptor, metazoa" CG8681 16-Dec-15 2015_12 ENSXETG00000017031(GRIK4) "phototaxis defective,viable,lethal" FBgn0053508 ppk13 pickpocket 13 http://flybase.net/reports/FBgn0053508.html "FBgn0032912, FBtr0081506, FBpp0081034" protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "CG33508, PPK13, CG14398" "IPR001873=Na+ channel, amiloride-sensitive" CG33508 16-Dec-15 2015_12 viable FBgn0033379 Mys45A Mystery 45A http://flybase.net/reports/FBgn0033379.html FBgn0062194 protein_coding_gene "0030036=actin cytoskeleton organization, 0022008=neurogenesis, 0042273=ribosomal large subunit biogenesis, 0000055=ribosomal large subunit export from nucleus" 0005730=nucleolus "Mys45a, anon-WO0118547.170, CG8070, Mystery, Mys-45A" "IPR007949=SDA1 domain, IPR016024=Armadillo-type fold, IPR012977=Uncharacterised domain NUC130/133, N-terminal, IPR027312=Sda1" CG8070 16-Dec-15 2015_12 ENSDARG00000068903(sdad1) YGR245C(SDA1) WBGene00012676(pro-3) ENSXETG00000020871(TNeu062m08.1) ENSMUSG00000029415(Sdad1) ENSG00000198301(SDAD1) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC07067 E -0.992750705 -0.336367895 1.712238022 -1.179810931 0.825241156 0.109580337 FBgn0267170 CR45610 http://flybase.net/reports/FBgn0267170.html non_protein_coding_gene CR45610 16-Dec-15 2015_12 FBgn0039444 TwdlD TweedleD http://flybase.net/reports/FBgn0039444.html protein_coding_gene 0008010=structural constituent of chitin-based larval cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix CG14243 IPR004145=Domain of unknown function DUF243 CG14243 16-Dec-15 2015_12 viable FBgn0265899 CR44688 http://flybase.net/reports/FBgn0265899.html non_protein_coding_gene lincRNA.656 CR44688 16-Dec-15 2015_12 FBgn0267972 Der-1 Derlin-1 http://flybase.net/reports/FBgn0267972.html "FBgn0031376, FBgn0065307" protein_coding_gene 0008233=peptidase activity "0034976=response to endoplasmic reticulum stress, 0043065=positive regulation of apoptotic process, 0030433=ER-associated ubiquitin-dependent protein catabolic process, 0006515=misfolded or incompletely synthesized protein catabolic process" 0005789=endoplasmic reticulum membrane "lethal (2) SH1964, l(2)SH2 1964, l(2)SH1964, Derlin-1, derlin-1, CG10908, Dm Derlin-1" IPR007599=Derlin CG10908 16-Dec-15 2015_12 ENSDARG00000021905(derl1) YDR411C(DFM1) WBGene00000843(cup-2) ENSXETG00000023186(derl1) ENSMUSG00000022365(Derl1) ENSG00000136986(DERL1) FBgn0005684 cpy clumpy http://flybase.net/reports/FBgn0005684.html gene 16-Dec-15 2015_12 "visible,recessive" "eye,rhabdomere,photoreceptor cell R2,photoreceptor cell R4" FBgn0001706 l(1)ESHS27 lethal (1) ESHS27 http://flybase.net/reports/FBgn0001706.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041202 Lipocalin Lipocalin http://flybase.net/reports/FBgn0041202.html gene Dmel.Lip 16-Dec-15 2015_12 FBgn0029702 CG15572 http://flybase.net/reports/FBgn0029702.html protein_coding_gene CG15572 16-Dec-15 2015_12 viable FBgn0263265 com2 http://flybase.net/reports/FBgn0263265.html gene 0008406=gonad development compaction defects 2 16-Dec-15 2015_12 gonad FBgn0058386 CG40386 http://flybase.net/reports/FBgn0058386.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000755 fs(1)A436 female sterile (1) A436 http://flybase.net/reports/FBgn0000755.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect" embryo FBgn0267626 CR45964 http://flybase.net/reports/FBgn0267626.html non_protein_coding_gene CR45964 16-Dec-15 2015_12 FBgn0051104 CG31104 http://flybase.net/reports/FBgn0051104.html FBgn0039314 protein_coding_gene CG13657 "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG31104 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" viable FBgn0043962 anon-19Ca anon-19Ca http://flybase.net/reports/FBgn0043962.html gene 16-Dec-15 2015_12 FBgn0035270 CG13933 http://flybase.net/reports/FBgn0035270.html protein_coding_gene 0035556=intracellular signal transduction dmASBa "IPR001496=SOCS box domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG13933 16-Dec-15 2015_12 "ENSDARG00000056468(asb16),ENSDARG00000071419(zgc:153279),ENSDARG00000069021,ENSDARG00000012948,ENSDARG00000034988(asb4)" "ENSXETG00000004879(asb1),ENSXETG00000025611(BC061350.1),ENSXETG00000025610(asb12),ENSXETG00000018158(ASB13)" viable FBgn0024893 dud dud http://flybase.net/reports/FBgn0024893.html gene "0007287=Nebenkern assembly, 0007291=sperm individualization" ms(2)Hb328 16-Dec-15 2015_12 "male sterile,recessive,partially lethal - majority die" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus,Nebenkern" FBgn0037436 Hr83 Hormone receptor 83 http://flybase.net/reports/FBgn0037436.html protein_coding_gene "0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding, 0043565=sequence-specific DNA binding, 0003707=steroid hormone receptor activity" "0006355=regulation of transcription, DNA-templated, 0043401=steroid hormone mediated signaling pathway" 0005634=nucleus "Drosophila hormone receptor 83, DHR83, CG10296, NR2E5" "IPR013088=Zinc finger, NHR/GATA-type, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001628=Zinc finger, nuclear hormone receptor-type" CG10296 16-Dec-15 2015_12 "viable,fertile" DRSC25662 K 0.873255297 0.386978935 -0.107382817 -0.185233339 -0.091751032 -1.634616063 FBgn0020527 mit(3)R2 mitotic R2 http://flybase.net/reports/FBgn0020527.html gene 16-Dec-15 2015_12 FBgn0034248 CG14483 http://flybase.net/reports/FBgn0034248.html protein_coding_gene IPR018625=Protein Pet100 CG14483 16-Dec-15 2015_12 WBGene00013161(Y53F4B.14) viable FBgn0262260 mir-2282 mir-2282 stem loop http://flybase.net/reports/FBgn0262260.html miRNA_gene "dme-mir-2282, miR-2282, CR42967" CR42967 16-Dec-15 2015_12 viable FBgn0039415 CG6142 http://flybase.net/reports/FBgn0039415.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016614=oxidoreductase activity, acting on CH-OH group of donors" 0055114=oxidation-reduction process "IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR012132=Glucose-methanol-choline oxidoreductase" CG6142 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) viable FBgn0024764 EC19 EC19 http://flybase.net/reports/FBgn0024764.html gene 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation" FBgn0040754 CG17059 http://flybase.net/reports/FBgn0040754.html FBgn0063276 protein_coding_gene 0051726=regulation of cell cycle BcDNA:GH04581 IPR029391=Myeloma-overexpressed 2-like CG17059 16-Dec-15 2015_12 ENSXETG00000026806(TGas041d06.1) viable FBgn0052544 CG32544 http://flybase.net/reports/FBgn0052544.html protein_coding_gene CG32544 16-Dec-15 2015_12 FBgn0040228 DCTN5-p25 "Dynactin 5, p25 subunit" http://flybase.net/reports/FBgn0040228.html "FBgn0001976, FBgn0028929" protein_coding_gene "2001019=positive regulation of retrograde axon cargo transport, 0007018=microtubule-based movement, 0007283=spermatogenesis" 0005869=dynactin complex "lethal group C4, DS00929.1, C4, BG:DS00929.1, l(2)35Bf, lethal(2)35Bf, br2, lethal 2 in the black-reduced region, CG10846, p25, dyn-p25, dynactin-subunit-p25, Dynactin subunit p-25, dynactin, p25 subunit, l(2)br2" "IPR001451=Hexapeptide repeat, IPR011004=Trimeric LpxA-like" CG10846 16-Dec-15 2015_12 ENSDARG00000003573(dctn5) WBGene00022118(Y71F9AL.14) ENSXETG00000010348(dctn5) ENSMUSG00000030868(Dctn5) ENSG00000166847(DCTN5) "lethal,recessive,male sterile,female sterile,partially lethal - majority die,visible" "macrochaeta & thoraxA400),macrochaeta & thorax64j),macrochaeta,wing,mesothoracic tergum" FBgn0005517 l(1)2Dh lethal (1) 2Dh http://flybase.net/reports/FBgn0005517.html gene "l(1)N5, N5, N2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051125 CG31125 http://flybase.net/reports/FBgn0051125.html FBgn0062423 protein_coding_gene BcDNA:SD02419 CG31125 16-Dec-15 2015_12 viable DRSC25124 IK 0.497681195 3.064095326 1.299976598 1.355885029 1.82492997 0.318881681 FBgn0036808 Dic4 Dicarboxylate carrier 4 http://flybase.net/reports/FBgn0036808.html protein_coding_gene "0022857=transmembrane transporter activity, 0005310=dicarboxylic acid transmembrane transporter activity" "0006835=dicarboxylic acid transport, 0055085=transmembrane transport, 0006839=mitochondrial transport" "0005739=mitochondrion, 0031966=mitochondrial membrane" "CG18363, DmDic4p" "IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG18363 16-Dec-15 2015_12 YLR348C(DIC1) viable FBgn0005562 M(3)65F Minute (3) 65F http://flybase.net/reports/FBgn0005562.html "FBgn0002613, FBgn0002614" gene "Minute(3)h of Schultz, M(3)h, M(3L)h, M(3)S37, M(3)h[S37], M(3)66A" 16-Dec-15 2015_12 "developmental rate defective,dominant,visible,Minute" macrochaeta FBgn0030761 CG9784 http://flybase.net/reports/FBgn0030761.html protein_coding_gene 0046030=inositol trisphosphate phosphatase activity "0016311=dephosphorylation, 0046856=phosphatidylinositol dephosphorylation" "lincRNA.S9473, IPP" "IPR000300=Inositol polyphosphate-related phosphatase, IPR005135=Endonuclease/exonuclease/phosphatase" CG9784 16-Dec-15 2015_12 YOL065C(INP54) WBGene00016802(C50C3.7) "ENSXETG00000022881(INPP5K),ENSXETG00000016154(INPP5J)" ENSMUSG00000006127(Inpp5k) ENSG00000132376(INPP5K) viable "synapse,neuromuscular junction" FBgn0045058 fs(1)162 female sterile (1) 162 http://flybase.net/reports/FBgn0045058.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "ovary,egg" FBgn0032439 Ref2 RNA and export factor binding protein 2 http://flybase.net/reports/FBgn0032439.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" 0006406=mRNA export from nucleus "CG17031, REF2, ref2, cg17031" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG17031 16-Dec-15 2015_12 YDR381W(YRA1) viable FBgn0085543 CG40950 http://flybase.net/reports/FBgn0085543.html FBan0040950 protein_coding_gene 16-Dec-15 2015_12 FBgn0064214 T:Rep-en Repressor domain of en http://flybase.net/reports/FBgn0064214.html engineered_tag T:en 16-Dec-15 2015_12 FBgn0019753 l(1)815-12 lethal (1) 815-12 http://flybase.net/reports/FBgn0019753.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082953 snoRNA:ë¬28S-612 snoRNA:ë¬28S-612 http://flybase.net/reports/FBgn0082953.html snoRNA_gene "CR34640, psi28s-612" CR34640 16-Dec-15 2015_12 FBgn0026640 l(2)k09315 lethal (2) k09315 http://flybase.net/reports/FBgn0026640.html gene 16-Dec-15 2015_12 FBgn0031460 CG15399 http://flybase.net/reports/FBgn0031460.html protein_coding_gene IPR027417=P-loop containing nucleoside triphosphate hydrolase CG15399 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC00413 E -1.037797951 -0.62101112 1.703992514 -1.937104701 FBgn0086044 snoRNA:Me28S-U1688 http://flybase.net/reports/FBgn0086044.html snoRNA_gene "Me28S-Um1688, CR34673" CR34673 16-Dec-15 2015_12 FBgn0263199 Galk Galactokinase http://flybase.net/reports/FBgn0263199.html "FBgn0262940, FBgn0035950" protein_coding_gene "0004335=galactokinase activity, 0005524=ATP binding" "0006012=galactose metabolic process, 0046835=carbohydrate phosphorylation" "0005737=cytoplasm, 0016020=membrane, 0070062=extracellular exosome" "CG5288, GALK, galactokinase, cg5288, CT16885, dGALK" "IPR019741=Galactokinase, conserved site, IPR006203=GHMP kinase, ATP-binding, conserved site, IPR019539=Galactokinase galactose-binding domain, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR000705=Galactokinase, IPR006204=GHMP kinase N-terminal domain, IPR013750=GHMP kinase, C-terminal domain, IPR006206=Mevalonate/galactokinase, IPR020568=Ribosomal protein S5 domain 2-type fold" CG5288 16-Dec-15 2015_12 ENSDARG00000004059(galk2) "YBR020W(GAL1),YDR009W(GAL3)" WBGene00006461(tag-96) ENSXETG00000008785(galk2) ENSMUSG00000027207(Galk2) ENSG00000156958(GALK2) FBgn0040305 MTF-1 Metal response element-binding Transcription Factor-1 http://flybase.net/reports/FBgn0040305.html "FBgn0035991, FBgn0062029" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000976=transcription regulatory region sequence-specific DNA binding, 0046872=metal ion binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006351=transcription, DNA-templated, 0006875=cellular metal ion homeostasis, 0034599=cellular response to oxidative stress, 0055069=zinc ion homeostasis, 0010038=response to metal ion, 1990170=stress response to cadmium ion, 0046688=response to copper ion" "0005737=cytoplasm, 0005634=nucleus" "metal responsive transcription factor 1, metal response element binding transcription factor, Mtf-1, metal-regulatory transcription factor 1, metal-responsive transcription factor-1, metal response element binding Transcription Factor 1, CG3743, metal response element-binding transcription factor-1, metal responsive transcription factor, Metal-responsive transcription factor 1, anon-WO0118547.411, mtf-1, dMTF-1, MTF-1" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR029796=Metal regulatory transcription factor 1, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG3743 16-Dec-15 2015_12 "chemical sensitive,short lived,chemical conditional,chemical resistant,long lived,oxidative stress response defective,starvation stress response defective,calorie restriction conditional,female sterile,visible,partially lethal - majority die,developmental rate defective,viable,fertile,recessive,lethal - all die before end of larval stage,some die during third instar larval stage,some die during pupal stage" "wing,mesothoracic tergum" DRSC21341 K -0.616102367 1.136536646 -0.471056923 -0.580371751 2.130648884 -0.061581028 FBgn0066344 laska laska http://flybase.net/reports/FBgn0066344.html gene "0008355=olfactory learning, 0007611=learning or memory" 16-Dec-15 2015_12 memory defective FBgn0042084 Bap26 Brahma associated protein 26kD http://flybase.net/reports/FBgn0042084.html gene 0035060=brahma complex BAP26 16-Dec-15 2015_12 FBgn0033913 CG8468 http://flybase.net/reports/FBgn0033913.html protein_coding_gene 0015355=secondary active monocarboxylate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG8468 16-Dec-15 2015_12 ENSDARG00000042807(zgc:158390) "YNL125C(ESBP6),YKL221W(MCH2)" ENSMUSG00000026220(Slc16a14) ENSG00000163053(SLC16A14) viable FBgn0003532 stmC stambha C http://flybase.net/reports/FBgn0003532.html gene stm-C 16-Dec-15 2015_12 "paralytic,recessive,heat sensitive" FBgn0005507 l(2)24EFe lethal (2) 24EFe http://flybase.net/reports/FBgn0005507.html gene l(2)Gr.V 16-Dec-15 2015_12 "lethal,recessive" FBgn0010055 JmX Ju myoX http://flybase.net/reports/FBgn0010055.html gene "Jm X, X" 16-Dec-15 2015_12 long lived FBgn0013933 E(Pc)17B E(Pc)17B http://flybase.net/reports/FBgn0013933.html gene E(Pc)14B 16-Dec-15 2015_12 FBgn0058418 CG40418 http://flybase.net/reports/FBgn0058418.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053452 5SrRNA:CR33452 5SrRNA:CR33452 http://flybase.net/reports/FBgn0053452.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33452 CR33452 16-Dec-15 2015_12 FBgn0035929 CG13311 http://flybase.net/reports/FBgn0035929.html FBgn0047130 protein_coding_gene 0005198=structural molecule activity BcDNA:RE29808 CG13311 16-Dec-15 2015_12 FBgn0267064 CR45508 http://flybase.net/reports/FBgn0267064.html non_protein_coding_gene CR45508 16-Dec-15 2015_12 FBgn0083290 E(smoDN)2042 Enhancer of smoDN 2042 http://flybase.net/reports/FBgn0083290.html gene 16-Dec-15 2015_12 FBgn0038621 CG10864 http://flybase.net/reports/FBgn0038621.html protein_coding_gene "0005267=potassium channel activity, 0015271=outward rectifier potassium channel activity" 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "IPR003280=Two pore domain potassium channel, IPR013099=Potassium channel domain" CG10864 16-Dec-15 2015_12 viable FBgn0264957 CR44126 http://flybase.net/reports/FBgn0264957.html non_protein_coding_gene lincRNA.251 CR44126 16-Dec-15 2015_12 FBgn0265930 CR44719 http://flybase.net/reports/FBgn0265930.html non_protein_coding_gene CR44719 16-Dec-15 2015_12 FBgn0267553 CR45893 http://flybase.net/reports/FBgn0267553.html non_protein_coding_gene CR45893 16-Dec-15 2015_12 FBgn0267522 28SrRNA-ë¬:CR45862 28S ribosomal RNA pseudogene:CR45862 http://flybase.net/reports/FBgn0267522.html pseudogene_attribute CR45862 CR45862 16-Dec-15 2015_12 FBgn0259328 C109 http://flybase.net/reports/FBgn0259328.html gene 16-Dec-15 2015_12 visible wing FBgn0263451 CR43474 http://flybase.net/reports/FBgn0263451.html non_protein_coding_gene CR43474 16-Dec-15 2015_12 FBgn0037753 CG12947 http://flybase.net/reports/FBgn0037753.html protein_coding_gene CG12947 16-Dec-15 2015_12 viable FBgn0267755 CR46086 http://flybase.net/reports/FBgn0267755.html non_protein_coding_gene CR46086 16-Dec-15 2015_12 FBgn0002038 l(2)37Db lethal (2) 37Db http://flybase.net/reports/FBgn0002038.html gene "E19, l(2)E19" 16-Dec-15 2015_12 "lethal,recessive" FBgn0266823 CR45285 http://flybase.net/reports/FBgn0266823.html non_protein_coding_gene CR45285 16-Dec-15 2015_12 FBgn0017373 l(2)C103 lethal (2) C103 http://flybase.net/reports/FBgn0017373.html gene C103 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0010556 l(2)03788 lethal (2) 03788 http://flybase.net/reports/FBgn0010556.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0005311 ms(2)73d male sterile (2) 73d http://flybase.net/reports/FBgn0005311.html gene 16-Dec-15 2015_12 "male sterile,recessive" spermatid FBgn0002019 l(2)37Ac lethal (2) 37Ac http://flybase.net/reports/FBgn0002019.html gene "37Ac, Ac, l(2)E145" 16-Dec-15 2015_12 lethal FBgn0259761 dolly-2 double loops of the Y 2 http://flybase.net/reports/FBgn0259761.html gene "0007283=spermatogenesis, 0051276=chromosome organization" "142-046, double loops of the Y-2, ms(3)142-46" 16-Dec-15 2015_12 "viable,male sterile" "Y chromosome loop,spermatozoon" FBgn0011084 l(1)Q42 lethal (1) Q42 http://flybase.net/reports/FBgn0011084.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0038504 Sur-8 Sur-8 http://flybase.net/reports/FBgn0038504.html protein_coding_gene 0017016=Ras GTPase binding "0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction" 0000164=protein phosphatase type 1 complex "CG5407, CT17146, Sur8, SUR-8" "IPR003591=Leucine-rich repeat, typical subtype, IPR027036=Leucine-rich repeat protein SHOC2, IPR001611=Leucine-rich repeat, IPR026906=Leucine rich repeat 5" CG5407 16-Dec-15 2015_12 ENSDARG00000040853(si:ch211-197i12.3) WBGene00004929(soc-2) ENSXETG00000023718(SHOC2) ENSMUSG00000024976(Shoc2) ENSG00000108061(SHOC2) viable FBgn0085193 CG34164 http://flybase.net/reports/FBgn0085193.html protein_coding_gene CG34164 16-Dec-15 2015_12 FBgn0005751 l(1)TK305 lethal (1) TK305 http://flybase.net/reports/FBgn0005751.html gene l305 16-Dec-15 2015_12 "lethal,recessive" FBgn0086907 Cyt-c-d Cytochrome c distal http://flybase.net/reports/FBgn0086907.html "FBgn0000408, FBgn0011213" protein_coding_gene "0020037=heme binding, 0045155=electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, 0009055=electron carrier activity" "0007291=sperm individualization, 0006119=oxidative phosphorylation, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0046669=regulation of compound eye retinal cell programmed cell death" "0005759=mitochondrial matrix, 0005829=cytosol, 0005743=mitochondrial inner membrane, 0005739=mitochondrion" "Cytc, CG13263, cytochrome c distal, cytochrome C, ms(2)04445, cyt c-d, dc3, cyt.c-d, DC3, Cytochrome c, cytochrome-c-d, cytochrome c-d, CytC, CytC-1, blanks, CYC, cytochrome c, cyt-c-d, bs30f07.y1, cyt.c, Cyt-c1, Cyt c, bln, Cyt C, Cytc-d, cyt c, pDMc02, CytC1, Cytochrome C" "IPR002327=Cytochrome c, class IA/ IB, IPR009056=Cytochrome c-like domain" CG13263 16-Dec-15 2015_12 "YJR048W(CYC1),YEL039C(CYC7)" "WBGene00017121(cyc-2.1),WBGene00013854(cyc-2.2)" " adult stage , larval stage--adult stage " " adult abdomen

, adult thorax

, adult head

" FBgn0002722 m(Est-6) modifier of Esterase 6 http://flybase.net/reports/FBgn0002722.html gene "m(Est6), m-est, M-est" 16-Dec-15 2015_12 FBgn0036534 DCP2 Decapping protein 2 http://flybase.net/reports/FBgn0036534.html FBgn0026583 protein_coding_gene "0050072=m7G(5')pppN diphosphatase activity, 0003723=RNA binding, 0030145=manganese ion binding, 0005515=protein binding" "0000290=deadenylation-dependent decapping of nuclear-transcribed mRNA, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0010603=regulation of cytoplasmic mRNA processing body assembly, 0035195=gene silencing by miRNA, 0000956=nuclear-transcribed mRNA catabolic process" "0005737=cytoplasm, 0000932=cytoplasmic mRNA processing body" "DCp2p, dDCP2, dDcp, dcp2, LD07107, Dcp2, dDcp2, DCP2, CG6169, BEST:LD07107" "IPR020084=NUDIX hydrolase, conserved site, IPR000086=NUDIX hydrolase domain, IPR007722=mRNA decapping protein 2, Box A, IPR015797=NUDIX hydrolase domain-like" CG6169 16-Dec-15 2015_12 "ENSDARG00000039016(dcp2),ENSDARG00000068388" YNL118C(DCP2) WBGene00003582(dcap-2) ENSXETG00000021514(dcp2) "lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,lethal" cytoplasmic mRNA processing body | germline clone DRSC10597 EK -0.508309891 -0.117026778 -2.84195425 -3.90546502 2.911549358 2.172683374 FBgn0032731 Swip-1 Swiprosin-1 http://flybase.net/reports/FBgn0032731.html protein_coding_gene 0005509=calcium ion binding 0007498=mesoderm development "0005886=plasma membrane, 0005927=muscle tendon junction" "efhd, EF-hand domain containing 2, efhd2, EFhd2, CG10641, Swiprosin-1, DSwip-1" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG10641 16-Dec-15 2015_12 "ENSDARG00000055759(si:dkey-72l14.9),ENSDARG00000043446(si:ch211-281l24.1)" ENSXETG00000012127(efhd1) "ENSMUSG00000040659(Efhd2),ENSMUSG00000026255(Efhd1)" "ENSG00000115468(EFHD1),ENSG00000142634(EFHD2)" "visible,partially lethal - majority die,some die during pharate adult stage,viable,fertile" mesothoracic tergum FBgn0011165 l(1)DM-2 lethal (1) DM-2 http://flybase.net/reports/FBgn0011165.html FBgn0010204 gene 16-Dec-15 2015_12 lethal FBgn0024222 IKKë_ I-kappaB kinase ë_ http://flybase.net/reports/FBgn0024222.html "FBgn0028725, FBgn0028726, FBgn0029099, FBgn0029160" protein_coding_gene "0008384=IkappaB kinase activity, 0005524=ATP binding, 0005515=protein binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0030163=protein catabolic process, 0045088=regulation of innate immune response, 0019731=antibacterial humoral response, 0019730=antimicrobial humoral response, 0008063=Toll signaling pathway, 0006468=protein phosphorylation, 0002230=positive regulation of defense response to virus by host, 0009950=dorsal/ventral axis specification, 0051607=defense response to virus, 0018105=peptidyl-serine phosphorylation, 0006963=positive regulation of antibacterial peptide biosynthetic process" "0005737=cytoplasm, 0008385=IkappaB kinase complex" "IRD5, Dmikkbeta, dIKK, DIK, dIKKbeta, IKK-like protein, Ikkbeta, DmIkkbeta, dmIKKbeta, Ird-5, LRK, Lipopolysaccharide activated kinase, Dmikkb, CG4201, immune response-deficient 5, Lak, DmIKKb, IKKbeta, Immune response deficient 5, Ik, anon-89Bd, mmune response deficient 5, ird, IK, dLak, LPS-responsive kinase, DmIKKbeta, IKK-beta, ird5/DmIkk[beta], DmIKK, Ird5, Ikkb, unnamed, ird-5, immune response deficient 5, ikk, ird5, IKK, cactus kinase, IKKB, DmIKKBeta, LPS-responsive-kinase, dIKK-beta, IRD-5, DLAK, IKKb" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG4201 16-Dec-15 2015_12 embryonic stage -- adult stage "immune response defective,viable,fertile,recessive,partially lethal - majority die" FBgn0000981 fs(2)HO294 female sterile (2) HO294 http://flybase.net/reports/FBgn0000981.html gene fs(2)294A 16-Dec-15 2015_12 FBgn0005083 fs(2)OW807 female sterile (2) OW807 http://flybase.net/reports/FBgn0005083.html gene 16-Dec-15 2015_12 FBgn0005057 fs(2)OW103 female sterile (2) OW103 http://flybase.net/reports/FBgn0005057.html gene 16-Dec-15 2015_12 FBgn0086519 Cpr47Eg Cuticular protein 47Eg http://flybase.net/reports/FBgn0086519.html "FBgn0061208, FBgn0033604, FBgn0047171" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "BcDNA:RE09259, Lcp2a, CG9070, Cpr47eg, Larval cuticle protein 2a" "IPR031305=Casein alpha/beta, conserved site, IPR000618=Insect cuticle protein" CG9070 16-Dec-15 2015_12 viable FBgn0033442 CG1690 http://flybase.net/reports/FBgn0033442.html protein_coding_gene CG1690 16-Dec-15 2015_12 viable DRSC06636 I 1.675317898 1.408913124 -0.268452981 1.010431759 0.164064832 0.337068218 FBgn0043852 vizhichai vizhichai http://flybase.net/reports/FBgn0043852.html gene 16-Dec-15 2015_12 FBgn0031115 CG11710 http://flybase.net/reports/FBgn0031115.html protein_coding_gene "0008270=zinc ion binding, 0016922=ligand-dependent nuclear receptor binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "IPR015947=PUA-like domain, IPR007374=ASCH domain, IPR009349=Zinc finger, C2HC5-type" CG11710 16-Dec-15 2015_12 ENSDARG00000005033(trip4) ENSXETG00000010649(TRIP4) ENSMUSG00000032386(Trip4) ENSG00000103671(TRIP4) "viable,fertile" FBgn0066304 Rpp20 Rpp20 http://flybase.net/reports/FBgn0066304.html "FBgn0031067, FBgn0052530, FBgn0053931, FBgn0061390, FBtr0089280, FBpp0088337, FBtr0089281, FBpp0088338" protein_coding_gene "0003676=nucleic acid binding, 0005515=protein binding, 0004526=ribonuclease P activity" 0008033=tRNA processing "0030678=mitochondrial ribonuclease P complex, 0030677=ribonuclease P complex, 0005737=cytoplasm, 0005634=nucleus" "CG32530-ORFA, CG32530, dRpp20, CG12533, CG33931, BcDNA:RE70209" "IPR002775=DNA/RNA-binding protein Alba-like, IPR014612=Ribonuclease P/MRP, subunit p20" CG33931 16-Dec-15 2015_12 ENSDARG00000036394(pop7) WBGene00013373(Y62E10A.2) ENSMUSG00000029715(Pop7) ENSG00000172336(POP7) DRSC19467 I -0.252305484 1.617374953 0.031056917 -0.890437835 -0.378523315 -0.463887417 FBgn0031834 CG13766 http://flybase.net/reports/FBgn0031834.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO16 CG13766 16-Dec-15 2015_12 viable FBgn0265905 CR44694 http://flybase.net/reports/FBgn0265905.html non_protein_coding_gene CR44694 16-Dec-15 2015_12 FBgn0065748 l(2)SH0501 lethal (2) SH0501 http://flybase.net/reports/FBgn0065748.html gene l(2)SH2 0501 16-Dec-15 2015_12 "lethal,recessive" FBgn0264324 spg sponge http://flybase.net/reports/FBgn0264324.html "FBgn0003472, FBgn0051048, FBgn0039605, FBgn0039607" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0090630=activation of GTPase activity, 0045466=R7 cell differentiation, 0007417=central nervous system development" "0005886=plasma membrane, 0005737=cytoplasm" "mat(3)6, mat3(6), Dock4, CG14530, Sponge, CG11754, CG31048, early-D, Dm Dock4" "IPR026791=Dedicator of cytokinesis, IPR001452=SH3 domain, IPR027357=DHR-2 domain, IPR027007=DHR-1 domain, IPR010703=Dedicator of cytokinesis C-terminal" CG31048 16-Dec-15 2015_12 "ENSDARG00000024874(dock4b),ENSDARG00000063180(LOC561387)" WBGene00000419(ced-5) ENSXETG00000009251(DOCK4) "ENSMUSG00000039716(Dock3),ENSMUSG00000035954(Dock4)" "ENSG00000088538(DOCK3),ENSG00000128512(DOCK4)" DRSC14373 K 0.514689583 -0.029580176 -0.674992531 -0.268635216 1.278231026 1.870291905 FBgn0034931 CG2812 http://flybase.net/reports/FBgn0034931.html protein_coding_gene "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG2812 16-Dec-15 2015_12 DRSC04319 E 0.110972793 -0.660044717 1.312456419 -2.172168795 -0.325159383 0.517171597 FBgn0053493 CG33493 http://flybase.net/reports/FBgn0053493.html FBgn0036100 protein_coding_gene CG6463 CG33493 16-Dec-15 2015_12 DRSC10642 K 0.787123651 0.548234082 -0.009949425 0.956559679 0.383486706 1.65407862 FBgn0039067 wda will decrease acetylation http://flybase.net/reports/FBgn0039067.html protein_coding_gene 0004402=histone acetyltransferase activity "0043970=histone H3-K9 acetylation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0043966=histone H3 acetylation" "0000124=SAGA complex, 0005634=nucleus" "CG4448, Wda, WDA, WFA" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR007582=TFIID subunit, WD40-associated region, IPR019775=WD40 repeat, conserved site" CG4448 16-Dec-15 2015_12 "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,visible" trichogen cell DRSC15579 IE 1.694845856 0.932294183 0.097777079 1.661479182 0.21828886 0.372780212 FBgn0050326 tRNA:CR30326 transfer RNA:CR30326 http://flybase.net/reports/FBgn0050326.html "FBgn0012008, FBgn0050226, FBgn0060027" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033449=GUU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:V:AAC:AE002787-b, CR30326, tRNA:val4:56D, tRNA[Val-AAC], tRNA[Val][[4]], chr2R.trna35-ValAAC, CR30226, transfer RNA:val4:56D, tRNA:V4:56D, valine tRNA, AE002787.trna52-ValAAC" CR30326 16-Dec-15 2015_12 FBgn0058096 CG40096 http://flybase.net/reports/FBgn0058096.html FBan0040096 protein_coding_gene 16-Dec-15 2015_12 FBgn0030100 CG12106 http://flybase.net/reports/FBgn0030100.html FBgn0064980 protein_coding_gene BcDNA:GH03263 "IPR017920=COMM domain, IPR009886=HCaRG" CG12106 16-Dec-15 2015_12 ENSMUSG00000051154(Commd3) ENSG00000148444(COMMD3) "viable,planar polarity defective" FBgn0015417 l(1)16ACa lethal (1) 16ACa http://flybase.net/reports/FBgn0015417.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014208 l(1)9-38-1 lethal (1) 9-38-1 http://flybase.net/reports/FBgn0014208.html gene l(1)14Cc 16-Dec-15 2015_12 "lethal,recessive" FBgn0260363 GSd248 http://flybase.net/reports/FBgn0260363.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0020290 l(2)M167 lethal (2) M167 http://flybase.net/reports/FBgn0020290.html gene 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive" FBgn0266808 CR45270 http://flybase.net/reports/FBgn0266808.html non_protein_coding_gene CR45270 16-Dec-15 2015_12 FBgn0051333 tRNA:CR31333 transfer RNA:CR31333 http://flybase.net/reports/FBgn0051333.html "FBgn0011990, FBgn0023420, FBgn0060039" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033440=ACG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Thr][[4]], chr3R.trna31-ThrCGT, tRNA:T:CGT:AE002708-c, CR31333, tRNA:T4:93A, AE002708.trna25-ThrCGT, tRNA[[Thr]], transfer RNA:thr4:93A, tRNA:T3:93AB, tRNA[Thr][[3]], tRNA:thr4:93A" CR31333 16-Dec-15 2015_12 FBgn0017610 Grt Glucose repressible transcripts http://flybase.net/reports/FBgn0017610.html gene 16-Dec-15 2015_12 FBgn0040646 CG14580 http://flybase.net/reports/FBgn0040646.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024237 fl338 fl338 http://flybase.net/reports/FBgn0024237.html gene 0007549=dosage compensation unnamed 16-Dec-15 2015_12 "lethal,female,dosage compensation defective" FBgn0259187 Ir60d Ionotropic receptor 60d http://flybase.net/reports/FBgn0259187.html "FBan0013582, FBgn0035015" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 60d, CG42291, DmelIR60d, IR60d, CG13582" CG42291 16-Dec-15 2015_12 FBgn0005097 Fs(2)Y12 Female sterile (2) Y12 http://flybase.net/reports/FBgn0005097.html gene fs(2)Y12 16-Dec-15 2015_12 "female sterile,semidominant" egg FBgn0261880 Taf Tripped-and-fell http://flybase.net/reports/FBgn0261880.html gene 16-Dec-15 2015_12 "paralytic,dominant,heat sensitive,neurophysiology defective,viable" FBgn0265189 sud1 sudestada1 http://flybase.net/reports/FBgn0265189.html "FBgn0051120, FBgn0042107" protein_coding_gene "0031418=L-ascorbic acid binding, 0031543=peptidyl-proline dioxygenase activity, 0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0006417=regulation of translation, 0019511=peptidyl-proline hydroxylation" "0005737=cytoplasm, 0005634=nucleus" "CG31120, CG44254, CG18761" "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR019601=Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG44254 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065080 snoRNA:Me18S-A1374 http://flybase.net/reports/FBgn0065080.html FBgn0053634 snoRNA_gene 0030555=RNA modification guide activity 0005730=nucleolus "snoRNA:122, Me18S-A1374(snoR122), Dm-122, snoR122, CR33634" CR33634 16-Dec-15 2015_12 FBgn0011074 l(1)Q27 lethal (1) Q27 http://flybase.net/reports/FBgn0011074.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0065371 l(2)SH1701 lethal (2) SH1701 http://flybase.net/reports/FBgn0065371.html gene l(2)SH2 1701 16-Dec-15 2015_12 "lethal,recessive" FBgn0039227 polybromo polybromo http://flybase.net/reports/FBgn0039227.html FBgn0044721 protein_coding_gene 0003682=chromatin binding "0031936=negative regulation of chromatin silencing, 0007480=imaginal disc-derived leg morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007306=eggshell chorion assembly, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "0005700=polytene chromosome, 0035060=brahma complex, 0070604=PBAF complex" "baf180, Bap180, anon-WO0140519.158, Pb, bap180, Polybromo, PB, CG11375, POLYBROMO, BAF180" "IPR015880=Zinc finger, C2H2-like, IPR009071=High mobility group box domain, IPR018359=Bromodomain, conserved site, IPR001487=Bromodomain, IPR001025=Bromo adjacent homology (BAH) domain" CG11375 16-Dec-15 2015_12 ENSDARG00000044186 "YLR357W(RSC2),YGR056W(RSC1)" WBGene00007042(pbrm-1) ENSXETG00000013671(PBRM1) ENSMUSG00000042323(Pbrm1) ENSG00000163939(PBRM1) "viable,fertile,visible,dominant,female sterile,homeotic,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,enhancer of variegation" "wing vein,ectopic,vitelline membrane,chorion,adult abdominal segment 6,adult abdominal segment 5" FBgn0029791 CG4096 http://flybase.net/reports/FBgn0029791.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0006508=proteolysis, 0042059=negative regulation of epidermal growth factor receptor signaling pathway" 0005578=proteinaceous extracellular matrix CT13580 "IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR024079=Metallopeptidase, catalytic domain, IPR010294=ADAM-TS Spacer 1, IPR013273=Peptidase M12B, ADAM-TS, IPR002870=Peptidase M12B, propeptide, IPR001590=Peptidase M12B, ADAM/reprolysin" CG4096 16-Dec-15 2015_12 "ENSDARG00000067549,ENSDARG00000041982(LOC569099)" WBGene00000082(adt-1) "ENSXETG00000007838(ADAMTS7),ENSXETG00000009863(ADAMTS12)" "ENSMUSG00000047497(Adamts12),ENSMUSG00000032363(Adamts7)" "ENSG00000151388(ADAMTS12),ENSG00000136378(ADAMTS7)" "viable,fertile,visible" "wing vein,ectopic,wing" FBgn0039355 CG4730 http://flybase.net/reports/FBgn0039355.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" 0006357=regulation of transcription from RNA polymerase II promoter 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR029795=SNAIL family, IPR007087=Zinc finger, C2H2" CG4730 16-Dec-15 2015_12 "viable,fertile" FBgn0044051 Ilp1 Insulin-like peptide 1 http://flybase.net/reports/FBgn0044051.html FBgn0036045 protein_coding_gene "0005158=insulin receptor binding, 0005179=hormone activity" 0008286=insulin receptor signaling pathway 0005615=extracellular space "Dilp1, DILP, insulin-like peptide, Dilp 1, dilp1, Ilp-1, Dilp, Dilp-1, Ilp, dilp, DILP1, dILP1, Ilp1, ilp1, dilp-1, CG14173, Drosophila insulin-like peptide 1, unnamed, DILP-1" "IPR022352=Insulin family, IPR016179=Insulin-like, IPR022353=Insulin, conserved site" CG14173 16-Dec-15 2015_12 "viable,small body" FBgn0267318 CR45754 http://flybase.net/reports/FBgn0267318.html non_protein_coding_gene CR45754 16-Dec-15 2015_12 FBgn0066132 E(sda)A E(sda)A http://flybase.net/reports/FBgn0066132.html gene "0009612=response to mechanical stimulus, 0007638=mechanosensory behavior" Line A 16-Dec-15 2015_12 bang sensitive FBgn0058116 CG40116 http://flybase.net/reports/FBgn0058116.html FBan0040116 protein_coding_gene 16-Dec-15 2015_12 FBgn0052254 CG32254 http://flybase.net/reports/FBgn0052254.html FBgn0064853 protein_coding_gene BcDNA:RH01388 16-Dec-15 2015_12 DRSC21905 K 0.77029418 -0.079294308 -0.352191149 -0.541997711 1.980851792 0.120688902 FBgn0000433 depl depressed-like http://flybase.net/reports/FBgn0000433.html gene "depressed-roof, dep[r]" 16-Dec-15 2015_12 "visible,partially lethal - majority live,body color defective" "wing,macrochaeta" FBgn0260299 GSd498 http://flybase.net/reports/FBgn0260299.html gene 16-Dec-15 2015_12 lethal FBgn0266023 CR44788 http://flybase.net/reports/FBgn0266023.html non_protein_coding_gene lincRNA.12 CR44788 16-Dec-15 2015_12 FBgn0010865 l(3)05408 lethal (3) 05408 http://flybase.net/reports/FBgn0010865.html FBgn0011308 gene l(3)j1B3 16-Dec-15 2015_12 "lethal,recessive" FBgn0040394 CG16903 http://flybase.net/reports/FBgn0040394.html "FBgn0029597, FBgn0066825" protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0019901=protein kinase binding" "0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "anon-WO03040301.211, EG:67A9.2" "IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal, IPR015429=Cyclin C/H/T/L" CG16903 16-Dec-15 2015_12 "ENSDARG00000055124(si:ch211-203b8.5),ENSDARG00000012140(ccnl1)" WBGene00000876(cyl-1) "ENSXETG00000012250(CCNL1),ENSXETG00000017379(CCNL2_XENTR)" "ENSMUSG00000027829(Ccnl1),ENSMUSG00000029068(Ccnl2)" "ENSG00000163660(CCNL1),ENSG00000221978(CCNL2)" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0065836 l(2)SH0336 lethal (2) SH0336 http://flybase.net/reports/FBgn0065836.html gene l(2)SH2 0336 16-Dec-15 2015_12 "lethal,recessive" FBgn0037232 CG9791 http://flybase.net/reports/FBgn0037232.html FBan0009791 protein_coding_gene "0003678=DNA helicase activity, 0003677=DNA binding, 0004004=ATP-dependent RNA helicase activity" 0032508=DNA duplex unwinding 0005759=mitochondrial matrix "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR022192=Mitochondrial degradasome RNA helicase subunit, C-terminal domain" CG9791 16-Dec-15 2015_12 YPL029W(SUV3) WBGene00007444(C08F8.2) ENSXETG00000008852(SUPV3L1) ENSMUSG00000020079(Supv3l1) ENSG00000156502(SUPV3L1) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12335 K -0.201561247 -0.564395001 -1.280551535 0.37742834 1.946842975 0.058877952 FBgn0041245 Gr39b Gustatory receptor 39b http://flybase.net/reports/FBgn0041245.html FBgn0051620 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG31620, GR39D.1, GR39b, 39D.1, Gr39D1, Gustatory receptor 39D.1, 39D1" IPR013604=7TM chemoreceptor CG31620 16-Dec-15 2015_12 viable DRSC01848 IK -1.956293302 1.418062416 0.49927517 -0.068433708 -1.969369262 -0.498308641 FBgn0028878 CG15269 http://flybase.net/reports/FBgn0028878.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "BG:DS04929.3, DS04929.3" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG15269 16-Dec-15 2015_12 "YPR015C(),YPR013C()" viable FBgn0034009 CG8155 http://flybase.net/reports/FBgn0034009.html "FBtr0087391, FBpp0086523" protein_coding_gene 0005096=GTPase activator activity "0007298=border follicle cell migration, 0008340=determination of adult lifespan, 0043087=regulation of GTPase activity" IPR000195=Rab-GTPase-TBC domain CG8155 16-Dec-15 2015_12 ENSMUSG00000039201(Tbc1d25) ENSG00000068354(TBC1D25) "long lived,visible,partially lethal - majority die,some die during pupal stage,cell migration defective" "trichogen cell,mesothoracic tergum,border follicle cell" FBgn0033635 CG7777 http://flybase.net/reports/FBgn0033635.html protein_coding_gene "0005372=water transmembrane transporter activity, 0015267=channel activity" 0055085=transmembrane transport 0016021=integral component of membrane Aqp7777 "IPR000425=Major intrinsic protein, IPR023271=Aquaporin-like" CG7777 16-Dec-15 2015_12 YPR192W(AQY1) "WBGene00000172(aqp-4),WBGene00000174(aqp-6),WBGene00000173(aqp-5)" viable FBgn0063393 sip sine prole http://flybase.net/reports/FBgn0063393.html gene "0007282=cystoblast division, 0007283=spermatogenesis, 0048477=oogenesis" 16-Dec-15 2015_12 "female sterile,recessive" "spermatozoon,spermatid,egg chamber,nurse cell,ovary,follicle cell" FBgn0265548 CR44398 http://flybase.net/reports/FBgn0265548.html non_protein_coding_gene lincRNA.176 CR44398 16-Dec-15 2015_12 FBgn0267549 CR45889 http://flybase.net/reports/FBgn0267549.html non_protein_coding_gene CR45889 16-Dec-15 2015_12 FBgn0027836 Dgp-1 Dgp-1 http://flybase.net/reports/FBgn0027836.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" CG5729 "IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal" CG5729 16-Dec-15 2015_12 "ENSDARG00000053467(gtpbp1),ENSDARG00000042900(gtpbp1l)" WBGene00000480(cgp-1) ENSXETG00000006894(gtpbp1) ENSMUSG00000042535(Gtpbp1) ENSG00000100226(GTPBP1) "viable,fertile,body color defective" mesothoracic tergum FBgn0033571 Rpb5 Rpb5 http://flybase.net/reports/FBgn0033571.html protein_coding_gene "0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity" "0006366=transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint" "0005665=DNA-directed RNA polymerase II, core complex" "CG11979, DmRPB5, RPB5" "IPR020608=RNA polymerase, subunit H/Rpb5, conserved site, IPR005571=RNA polymerase, Rpb5, N-terminal, IPR014381=DNA-directed RNA polymerase RPB5 subunit, eukaryote/virus, IPR000783=RNA polymerase, subunit H/Rpb5 C-terminal, IPR020609=Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit" CG11979 16-Dec-15 2015_12 YBR154C(RPB5) WBGene00019246(rpb-5) ENSXETG00000003291(polr2e) ENSMUSG00000004667(Polr2e) ENSG00000099817(POLR2E) DRSC06100 IEK -0.798890607 1.895526195 -4.049868687 -0.928224466 1.34282151 4.602999553 FBgn0027324 l(1)G0041 lethal (1) G0041 http://flybase.net/reports/FBgn0027324.html gene 16-Dec-15 2015_12 "lethal,melanotic mass phenotype,recessive" melanotic mass FBgn0030536 CG11068 http://flybase.net/reports/FBgn0030536.html protein_coding_gene CG11068 16-Dec-15 2015_12 viable FBgn0013668 ms(3)neo4 ms(3)neo4 http://flybase.net/reports/FBgn0013668.html gene unnamed 16-Dec-15 2015_12 "semi-sterile,male sterile" FBgn0053099 CG33099 http://flybase.net/reports/FBgn0053099.html FBgn0038982 protein_coding_gene 0045544=gibberellin 20-oxidase activity 0055114=oxidation-reduction process CG5340 "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR026992=Non-haem dioxygenase N-terminal domain, IPR027443=Isopenicillin N synthase-like" CG33099 16-Dec-15 2015_12 viable FBgn0058363 CG40363 http://flybase.net/reports/FBgn0058363.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028980 tan tantalus http://flybase.net/reports/FBgn0028980.html FBgn0035668 protein_coding_gene 0007423=sensory organ development "0005737=cytoplasm, 0005634=nucleus" "Tantalus, CG6586" IPR028149=Tantalus-like CG6586 16-Dec-15 2015_12 "viable,visible,fertile,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "interocellar bristle,eye,ommatidium,interommatidial bristle,supernumerary,macrochaeta,scutellar bristle,abdominal sternite bristle,ectopic,abdominal tergite & macrochaeta,abdominal tergite & macrochaeta | ectopic,wing vein L5,postvertical bristle,wing vein,sex comb,joint,tarsal segment,wing,wing margin,macrochaeta & thorax-537.4,ocellar bristle" FBgn0086397 BG02320 http://flybase.net/reports/FBgn0086397.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0051260 CG31260 http://flybase.net/reports/FBgn0051260.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262459 mir-34 mir-34 stem loop http://flybase.net/reports/FBgn0262459.html "FBgn0064158, FBgn0053326, FBgn0262326" miRNA_gene 0003730=mRNA 3'-UTR binding "1901215=negative regulation of neuron death, 0046716=muscle cell cellular homeostasis, 0035195=gene silencing by miRNA" "miR-34, mir-34, CR33326, Mir-34, dme-mir-34, dme-miR-34-5p, 34, CR43033, dme-miR-34" CR43033 16-Dec-15 2015_12 " larval stage--prepupal stage , adult stage " "viable,lethal,long lived,short lived,gravitaxis defective,conditional,heat stress response defective,neuroanatomy defective" "wing,adult brain,conditional" FBgn0035198 CG9133 http://flybase.net/reports/FBgn0035198.html "FBgn0044576, FBgn0044735, FBgn0046290, FBgn0046291, FBgn0052332, FBtr0072654, FBpp0072548, FBtr0072655, FBpp0072549, FBtr0072656, FBpp0072550, FBtr0072657, FBpp0072551, FBtr0072658, FBpp0072552" protein_coding_gene "anon-WO0140519.53, BEST:GH19464, anon-WO0140519.145, bs29f09.y1, BEST:GH19274, AT07490, CG32332" CG9133 16-Dec-15 2015_12 FBgn0084058 l(3)82CDe lethal (3) 82CDe http://flybase.net/reports/FBgn0084058.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0062567 Mod(var)E646 Mod(var)E646 http://flybase.net/reports/FBgn0062567.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" E646 16-Dec-15 2015_12 "partially lethal - majority die,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002794 ms(1)1 male sterile (1) 1 http://flybase.net/reports/FBgn0002794.html gene 16-Dec-15 2015_12 "male sterile,female fertile,viable" "spermatid axoneme,spermatid" FBgn0028571 ren renegade http://flybase.net/reports/FBgn0028571.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263945 BG00528 http://flybase.net/reports/FBgn0263945.html gene 16-Dec-15 2015_12 "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0025481 ms(3)85E male sterile (3) 85E http://flybase.net/reports/FBgn0025481.html gene ms(3)KM27 16-Dec-15 2015_12 male sterile FBgn0265691 CR44498 http://flybase.net/reports/FBgn0265691.html non_protein_coding_gene CR44498 16-Dec-15 2015_12 FBgn0002531 Lcp1 Larval cuticle protein 1 http://flybase.net/reports/FBgn0002531.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0008363=larval chitin-based cuticle development, 0040003=chitin-based cuticle development" 0031012=extracellular matrix "Gene I, DMLCP1, lcp1, L[[3]]CP1, CG11650, 1, CP1, I, LCP-1, DmelLcp1, cuticle p. I, LCP1" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG11650 16-Dec-15 2015_12 " larval stage | late third instar larval stage , larval stage | third instar stage 2 " " organism

, integumentary system

" "electrophoretic variant,viable" FBgn0267588 CR45926 http://flybase.net/reports/FBgn0267588.html non_protein_coding_gene Mgn3564 CR45926 16-Dec-15 2015_12 FBgn0065444 l(2)SH1445 lethal (2) SH1445 http://flybase.net/reports/FBgn0065444.html gene l(2)SH2 1445 16-Dec-15 2015_12 "lethal,recessive" FBgn0024182 waw waclaw http://flybase.net/reports/FBgn0024182.html "FBgn0014083, FBgn0052527, FBtr0077200, FBpp0076899, FBtr0077201, FBpp0076900, FBtr0077202, FBpp0076901" protein_coding_gene "0003746=translation elongation factor activity, 0005525=GTP binding, 0003924=GTPase activity" 0006412=translation "tu2, CG32527, anon-19Fb, CG1410" "IPR009022=Elongation factor G, III-V domain, IPR006297=Elongation factor 4, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000640=Translation elongation factor EFG, V domain, IPR005225=Small GTP-binding protein domain, IPR031157=Tr-type G domain, conserved site, IPR013842=GTP-binding protein LepA, C-terminal, IPR000795=Transcription factor, GTP-binding domain" CG1410 16-Dec-15 2015_12 ENSDARG00000029088(im:6906935) YLR289W(GUF1) WBGene00022862(ZK1236.1) ENSXETG00000008432(GUF1) ENSMUSG00000029208(Guf1) ENSG00000151806(GUF1) "viable,fertile" FBgn0037986 CG14736 http://flybase.net/reports/FBgn0037986.html protein_coding_gene 0016020=membrane "IPR001107=Band 7 protein, IPR001972=Stomatin family" CG14736 16-Dec-15 2015_12 FBgn0260331 GSd113 http://flybase.net/reports/FBgn0260331.html gene 16-Dec-15 2015_12 lethal FBgn0045974 PdL45C1 PdL45C1 http://flybase.net/reports/FBgn0045974.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0266656 CR45163 http://flybase.net/reports/FBgn0266656.html non_protein_coding_gene CR45163 16-Dec-15 2015_12 FBgn0005016 dipp-7 defective in phototaxis plasticity 7 http://flybase.net/reports/FBgn0005016.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0031436 ND-B17.2 NADH dehydrogenase (ubiquinone) B17.2 subunit http://flybase.net/reports/FBgn0031436.html "FBgn0025287, FBgn0063253" protein_coding_gene "0009055=electron carrier activity, 0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH-ubiquinone oxidoreductase subunit B17.2, B17.2, BcDNA:GH12382, FBpp0077425, NADH ubiquinone oxidoreductase B17.2, N7BM, NADH:ubiquinone oxidoreductase B17.2 subunit, anon-EST:Posey62, CG3214" IPR007763=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 CG3214 16-Dec-15 2015_12 ENSDARG00000042469(ndufa12) WBGene00022380(Y94H6A.8) ENSXETG00000023839(dap13) ENSMUSG00000020022(Ndufa12) ENSG00000184752(NDUFA12) "viable,visible" trichogen cell FBgn0260267 GSd318 http://flybase.net/reports/FBgn0260267.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0005451 l(1)v231 lethal (1) v231 http://flybase.net/reports/FBgn0005451.html gene l(1)231 16-Dec-15 2015_12 FBgn0016882 l(2)39DEg lethal (2) 39DEg http://flybase.net/reports/FBgn0016882.html gene K213 16-Dec-15 2015_12 lethal FBgn0005088 fs(2)OW812 female sterile (2) OW812 http://flybase.net/reports/FBgn0005088.html gene 16-Dec-15 2015_12 FBgn0002300 l(3)81Fa lethal (3) 81Fa http://flybase.net/reports/FBgn0002300.html gene "l(3)Rh1, 81Fa" 16-Dec-15 2015_12 lethal FBgn0001149 GstD1 Glutathione S transferase D1 http://flybase.net/reports/FBgn0001149.html FBgn0010045 protein_coding_gene "0004364=glutathione transferase activity, 0018833=DDT-dehydrochlorinase activity" 0006749=glutathione metabolic process 0005737=cytoplasm "GST-D1, dmGSTD1, DmGST1, gstD, G-S-T, CG10045 Glutathione S-transferase, Glutathione-S-transferase 1, Glutathione S-transferase-D1, CG10045, gstD1, gstd1, GSTase, GST1-1, Glutathione S-transferase D1, DmGSTD1, Gst1-1, glutathione S-transferase D1, Gst1.1, D1, GstD, unnamed, GST-1, Gst, DmGst1, Gst1, GST, Glutathione S-transferase 1, GSt1-1, GSTD1, DmGST-1, GST1, Gst-D1, T5, gst-D, DmGSTD1-1, gst-D1-1" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG10045 16-Dec-15 2015_12 YNL229C(URE2) adult stage viable FBgn0031458 aph-1 anterior pharynx defective 1 http://flybase.net/reports/FBgn0031458.html FBgn0013528 protein_coding_gene 0004175=endopeptidase activity "0007219=Notch signaling pathway, 0016485=protein processing, 0008593=regulation of Notch signaling pathway, 0043085=positive regulation of catalytic activity" "0070765=gamma-secretase complex, 0005887=integral component of plasma membrane, 0005770=late endosome, 0055037=recycling endosome, 0005886=plasma membrane, 0016021=integral component of membrane" "presenilin stabilization factor, Anterior pharynx defective 1, aph1, presenilin enhancer-1, CG2855, l(2)23AB6, l(2)23Ag, dAph-1, Pen-1, Aph1, pen-1, Aph-1, aph, Dm APH-1" IPR009294=Gamma-secretase subunit Aph-1 CG2855 16-Dec-15 2015_12 "ENSDARG00000005612(aph1b),ENSDARG00000052668(zgc:114200)" WBGene00000147(aph-1) ENSXETG00000016439(Q5EB22_XENTR) "ENSMUSG00000053040(Aph1c),ENSMUSG00000032375(Aph1b),ENSMUSG00000040323(Gm15429),ENSMUSG00000015750(Aph1a)" "ENSG00000117362(APH1A),ENSG00000138613(APH1B)" "neuroanatomy defective,lethal,recessive,size defective,dominant,partially lethal,viable,visible" "embryonic/larval optic lobe,presumptive embryonic/larval nervous system,sensory mother cell & dorsal mesothoracic disc,wing,microchaeta,eye,macrochaeta,germline clone,maternal effect,tormogen cell" FBgn0041117 l(2)k09834 lethal (2) k09834 http://flybase.net/reports/FBgn0041117.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030403 CG1824 http://flybase.net/reports/FBgn0030403.html protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" 0055085=transmembrane transport "0005743=mitochondrial inner membrane, 0016021=integral component of membrane" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain" CG1824 16-Dec-15 2015_12 ENSDARG00000056672(abcb8) WBGene00001816(haf-6) ENSXETG00000011958(ABCB8) ENSMUSG00000028973(Abcb8) ENSG00000197150(ABCB8) viable FBgn0086782 amn amnesiac http://flybase.net/reports/FBgn0086782.html "FBgn0000076, FBgn0015274" protein_coding_gene "0001664=G-protein coupled receptor binding, 0005184=neuropeptide hormone activity" "0007612=learning, 0007613=memory, 0019933=cAMP-mediated signaling, 0008016=regulation of heart contraction, 0007619=courtship behavior, 0040040=thermosensory behavior, 0048149=behavioral response to ethanol, 0042066=perineurial glial growth, 0006171=cAMP biosynthetic process, 0072375=medium-term memory, 0007616=long-term memory, 0007615=anesthesia-resistant memory, 0008355=olfactory learning, 0007190=activation of adenylate cyclase activity, 0009408=response to heat, 0008049=male courtship behavior, 0019730=antimicrobial humoral response, 0007476=imaginal disc-derived wing morphogenesis, 0007218=neuropeptide signaling pathway, 0007611=learning or memory, 0048266=behavioral response to pain" 0005615=extracellular space "PACAP38, Pituitary adenylyl cyclase-activating polypeptide-like, Pacap38, PACAP38-like, chpd, PACAP-like, Amnesiac, PACAP, Drm-amn, CG11937, PACAP-38, cheap date, cheapdate, Pituitary adenylyl cyclase-activating polypeptide, EP(X)1442, Amn" CG11937 16-Dec-15 2015_12 FBgn0260070 2L1554 http://flybase.net/reports/FBgn0260070.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive,viable" "embryonic/larval tracheal system,somatic clone" FBgn0039075 CG4393 http://flybase.net/reports/FBgn0039075.html protein_coding_gene "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006020=PTB/PI domain, IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG4393 16-Dec-15 2015_12 WBGene00007520(C11E4.6) ENSXETG00000015109(ANKS1A) ENSMUSG00000024219(Anks1) "ENSG00000185046(ANKS1B),ENSG00000064999(ANKS1A)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266202 CR44897 http://flybase.net/reports/FBgn0266202.html non_protein_coding_gene CR44897 16-Dec-15 2015_12 FBgn0032612 CG13282 http://flybase.net/reports/FBgn0032612.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG13282 16-Dec-15 2015_12 viable FBgn0017410 ci::en ci::en http://flybase.net/reports/FBgn0017410.html engineered_fusion_gene 16-Dec-15 2015_12 "wing vein L3,wing vein L4,gastric caecum primordium" FBgn0023141 WppB White prepupal locus B http://flybase.net/reports/FBgn0023141.html gene "5, 2" 16-Dec-15 2015_12 FBgn0250899 zaa90g02 http://flybase.net/reports/FBgn0250899.html gene zaa90g02y1 16-Dec-15 2015_12 FBgn0083058 snoRNA:ë¬18S-1086 snoRNA:ë¬18S-1086 http://flybase.net/reports/FBgn0083058.html snoRNA_gene "psi18s-1086, CR34633, Psi 18S-1086" CR34633 16-Dec-15 2015_12 FBgn0061113 l(3)S005916b lethal (3) S005916b http://flybase.net/reports/FBgn0061113.html gene 0059/16 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal" FBgn0262820 CG43191 http://flybase.net/reports/FBgn0262820.html protein_coding_gene noncoding_6153 CG43191 16-Dec-15 2015_12 FBgn0016949 tilF touch insensitive larva F http://flybase.net/reports/FBgn0016949.html gene line 70 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" "embryonic/larval central nervous system,embryonic/larval peripheral nervous system" FBgn0010339 128up upstream of RpIII128 http://flybase.net/reports/FBgn0010339.html "FBgn0010196, FBtr0087976, FBpp0087084" protein_coding_gene 0005525=GTP binding "CG8340, Gtp-bp, GTP-bp, X71866" "IPR006073=GTP binding domain, IPR004095=TGS, IPR012676=TGS-like, IPR006074=GTP1/OBG, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR031167=OBG-type guanine nucleotide-binding (G) domain" CG8340 16-Dec-15 2015_12 ENSDARG00000039345(drg1) YAL036C(RBG1) WBGene00012126(T28D6.6) ENSXETG00000004191(drg1) ENSMUSG00000020457(Drg1) ENSG00000185721(DRG1) " adult stage , embryonic stage " viable FBgn0038419 CG14879 http://flybase.net/reports/FBgn0038419.html FBgn0063684 protein_coding_gene 0030246=carbohydrate binding BcDNA:RE20991 "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001079=Galectin, carbohydrate recognition domain" CG14879 16-Dec-15 2015_12 viable FBgn0061193 Src64B::unc-5 Src64B::unc-5 http://flybase.net/reports/FBgn0061193.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0002887 mus201 mutagen-sensitive 201 http://flybase.net/reports/FBgn0002887.html "FBgn0015712, FBgn0052956, FBtr0079668, FBpp0079283, FBtr0079669, FBpp0079284, FBtr0079670, FBpp0079285, FBtr0079671, FBpp0079286, FBtr0079672, FBpp0079287" protein_coding_gene "0003697=single-stranded DNA binding, 0000014=single-stranded DNA endodeoxyribonuclease activity" "0006289=nucleotide-excision repair, 0070914=UV-damage excision repair, 0006284=base-excision repair" 0005634=nucleus "XPG[Dm], CG10890, 55A11T, xpg/mus201, mus-201, ESTS:55A11T, rad202, XPG[DM], DmXPG, CG32956, XPG, mus(2)201" "IPR006084=XPG/Rad2 endonuclease, IPR001044=XPG/Rad2 endonuclease, eukaryotes, IPR008918=Helix-hairpin-helix motif, class 2, IPR019974=XPG conserved site, IPR006086=XPG-I domain, IPR020045=5'-3' exonuclease, C-terminal domain, IPR006085=XPG N-terminal, IPR003903=Ubiquitin interacting motif, IPR029060=PIN domain-like" CG10890 16-Dec-15 2015_12 YGR258C(RAD2) WBGene00019004(xpg-1) ENSXETG00000002745(ERCC5) ENSMUSG00000026048(Ercc5) ENSG00000134899(BIVM-ERCC5) "viable,chemical sensitive,recessive,DNA repair defective,fertile,lethal,partially,radiation sensitive,increased cell death,conditional,female fertile" "eye,conditional" FBgn0031885 Mnn1 Menin 1 http://flybase.net/reports/FBgn0031885.html FBgn0053266 protein_coding_gene "0031571=mitotic G1 DNA damage checkpoint, 0010212=response to ionizing radiation, 0001666=response to hypoxia, 0046529=imaginal disc fusion, thorax closure, 0048728=proboscis development, 0006979=response to oxidative stress, 0051568=histone H3-K4 methylation, 0046330=positive regulation of JNK cascade, 0036297=interstrand cross-link repair, 0009408=response to heat, 0006974=cellular response to DNA damage stimulus, 0006289=nucleotide-excision repair, 0009651=response to salt stress, 0008340=determination of adult lifespan, 0046329=negative regulation of JNK cascade" "0044665=MLL1/2 complex, 0005634=nucleus" "mnn1, menin, CG13778, Menin, CG33266, MEN1, Menin1" IPR007747=Menin CG13778 16-Dec-15 2015_12 ENSDARG00000058021(men1) ENSXETG00000008433(MEN1) ENSMUSG00000024947(Men1) ENSG00000133895(MEN1) "viable,fertile,stress response defective,chemical sensitive,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage,lethal,conditional,radiation sensitive,DNA repair defective,wild-type,short lived,male,melanotic mass phenotype,lethal - all die before end of P-stage,some die during pharate adult stage" "distiproboscis,wing,adult thorax,chaeta" FBgn0000880 fs(1)M78 female sterile (1) M78 http://flybase.net/reports/FBgn0000880.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0263537 mir-4951 mir-4951 stem loop http://flybase.net/reports/FBgn0263537.html miRNA_gene "dme-mir-4951, CR43522" CR43522 16-Dec-15 2015_12 viable FBgn0031307 MFS3 Major Facilitator Superfamily Transporter 3 http://flybase.net/reports/FBgn0031307.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport "0016021=integral component of membrane, 0005886=plasma membrane, 0005829=cytosol" CG4726 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG4726 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" FBgn0050008 CG30008 http://flybase.net/reports/FBgn0050008.html "FBgn0033462, FBgn0044623" protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane "anon-WO0140519.246, CG12138" IPR002076=ELO family CG30008 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0263525 mir-4911 mir-4911 stem loop http://flybase.net/reports/FBgn0263525.html miRNA_gene "CR43510, dme-mir-4911" CR43510 16-Dec-15 2015_12 FBgn0037231 Vps24 Vacuolar protein sorting 24 http://flybase.net/reports/FBgn0037231.html FBan0009779 protein_coding_gene "0006909=phagocytosis, 0007034=vacuolar transport, 0070676=intralumenal vesicle formation" 0000815=ESCRT III complex "ESCRT, Vps24, DmVPS24, CG9779, dvps24, vps24, Charged multivesicular body protein 3" IPR005024=Snf7 family CG9779 16-Dec-15 2015_12 ENSDARG00000038064(vps24) YKL041W(VPS24) WBGene00020866(T27F7.1) ENSXETG00000017980(vps24) ENSMUSG00000053119(Vps24) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC12332 I -0.390687981 1.520651184 0.089116212 0.480321887 0.024683216 -0.458769256 FBgn0060774 l(3)S061301b lethal (3) S061301b http://flybase.net/reports/FBgn0060774.html gene 0613/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0033145 CG12828 http://flybase.net/reports/FBgn0033145.html protein_coding_gene CG12828 16-Dec-15 2015_12 FBgn0065562 l(2)SH0987 lethal (2) SH0987 http://flybase.net/reports/FBgn0065562.html gene l(2)SH2 0987 16-Dec-15 2015_12 "lethal,recessive" FBgn0038914 fit female-specific independent of transformer http://flybase.net/reports/FBgn0038914.html protein_coding_gene "CG17820, independent of transformer, female sterile independent of transformer" CG17820 16-Dec-15 2015_12 viable FBgn0041154 flk flanker http://flybase.net/reports/FBgn0041154.html gene 16-Dec-15 2015_12 FBgn0004076 segB short egg B http://flybase.net/reports/FBgn0004076.html gene 16-Dec-15 2015_12 FBgn0060786 l(3)S059613 lethal (3) S059613 http://flybase.net/reports/FBgn0060786.html gene 0596/13 16-Dec-15 2015_12 FBgn0016042 lup-4 loop unfolding protein 4 http://flybase.net/reports/FBgn0016042.html gene "0007283=spermatogenesis, 0007140=male meiosis, 0051276=chromosome organization" "ms(2)HA30, ms(2)HA10" 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective,male" "Y chromosome loop,spermatocyte,spermatid,spermatozoon" FBgn0264988 CG44139 http://flybase.net/reports/FBgn0264988.html protein_coding_gene CG44139 16-Dec-15 2015_12 FBgn0022126 l(2)k06502 lethal (2) k06502 http://flybase.net/reports/FBgn0022126.html FBgn0022292 gene l(2)02839 16-Dec-15 2015_12 "lethal,recessive" FBgn0044414 Scim13 Sensitized chromosome inheritance modifier 13 http://flybase.net/reports/FBgn0044414.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0032225 CG5022 http://flybase.net/reports/FBgn0032225.html protein_coding_gene 0008092=cytoskeletal protein binding "0005737=cytoplasm, 0019898=extrinsic component of membrane, 0005856=cytoskeleton" "IPR018980=FERM, C-terminal PH-like domain, IPR019748=FERM central domain, IPR000798=Ezrin/radixin/moesin-like, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000299=FERM domain, IPR014847=FERM adjacent (FA), IPR018979=FERM, N-terminal, IPR029071=Ubiquitin-related domain" CG5022 16-Dec-15 2015_12 ENSDARG00000059885(LOC100331256) WBGene00001491(frm-4) ENSXETG00000016772(FRMD3) "ENSMUSG00000049122(Frmd3),ENSMUSG00000027238(Frmd5)" "ENSG00000172159(FRMD3),ENSG00000171877(FRMD5)" viable FBgn0003656 sws swiss cheese http://flybase.net/reports/FBgn0003656.html FBgn0004059 protein_coding_gene "0004622=lysophospholipase activity, 0005515=protein binding" "0006644=phospholipid metabolic process, 0051402=neuron apoptotic process, 0007420=brain development, 0046470=phosphatidylcholine metabolic process, 0007608=sensory perception of smell, 0045494=photoreceptor cell maintenance, 0061024=membrane organization, 0006643=membrane lipid metabolic process" "0005737=cytoplasm, 0005789=endoplasmic reticulum membrane, 0005886=plasma membrane" "PNPLA6, Sws, CG2212, olfE, Swisscheese, olfactory E, Swiss cheese, swisscheese, Swiss Cheese, olfactory-E, swiss-cheese" "IPR001423=Lysophospholipase patatin, conserved site, IPR000595=Cyclic nucleotide-binding domain, IPR002641=Patatin/Phospholipase A2-related, IPR018490=Cyclic nucleotide-binding-like, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase, IPR014710=RmlC-like jelly roll fold" CG2212 16-Dec-15 2015_12 "ENSDARG00000040002(pnpla7),ENSDARG00000010773" YML059C(NTE1) WBGene00022718(ZK370.4) "ENSMUSG00000036833(Pnpla7),ENSMUSG00000004565(Pnpla6)" "ENSG00000130653(PNPLA7),ENSG00000032444(PNPLA6)" " adult stage , embryonic stage -- adult stage " adult head

"viable,smell perception defective,recessive,neuroanatomy defective,short lived" "adult brain,cell body rind of lamina,neuropil,CNS glial cell,epithelial glial cell,eye photoreceptor cell" FBgn0022349 CG1910 http://flybase.net/reports/FBgn0022349.html "FBgn0061695, FBgn0062042" protein_coding_gene 0007616=long-term memory "0005634=nucleus, 0005654=nucleoplasm" "anon-EST:fe1A3, anon-fast-evolving-1A3, anon-WO0118547.398, Anon1A3, anon1A3, unnamed, anon-WO0118547.745, 1A3" CG1910 16-Dec-15 2015_12 "viable,visible" "macrochaeta,trichogen cell" FBgn0061000 l(3)S026905 lethal (3) S026905 http://flybase.net/reports/FBgn0061000.html gene 0269/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0043995 Su(rst)D124 Su(rst)D124 http://flybase.net/reports/FBgn0043995.html gene 0001745=compound eye morphogenesis D124 16-Dec-15 2015_12 viable FBgn0013446 fs(1)ë_a5 fs(1)ë_a5 http://flybase.net/reports/FBgn0013446.html gene 16-Dec-15 2015_12 FBgn0015362 anon-k anon-k http://flybase.net/reports/FBgn0015362.html repeat_region 16-Dec-15 2015_12 FBgn0041732 mini-dumpy mini-dumpy http://flybase.net/reports/FBgn0041732.html gene 16-Dec-15 2015_12 FBgn0040235 c12.1 c12.1 http://flybase.net/reports/FBgn0040235.html FBgn0030126 protein_coding_gene 0003723=RNA binding "0007052=mitotic spindle organization, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005634=nucleus" "C12.1, cwc15, CG12135" IPR006973=Pre-mRNA-splicing factor Cwf15/Cwc15 CG12135 16-Dec-15 2015_12 ENSDARG00000013382(zgc:86607) WBGene00011687(T10C6.5) ENSXETG00000007076(CWC15) ENSMUSG00000004096(Cwc15) ENSG00000150316 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0028512 BG:DS07721.1 BG:DS07721.1 http://flybase.net/reports/FBgn0028512.html gene DS07721.1 16-Dec-15 2015_12 FBgn0001338 l(1)1Bc lethal (1) 1Bc http://flybase.net/reports/FBgn0001338.html gene "EC5, l(1)EC5" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005768 L12 L12 http://flybase.net/reports/FBgn0005768.html gene 16-Dec-15 2015_12 FBgn0038956 CG5379 http://flybase.net/reports/FBgn0038956.html protein_coding_gene "0004089=carbonate dehydratase activity, 0008270=zinc ion binding" 0006730=one-carbon metabolic process "IPR001148=Alpha carbonic anhydrase, IPR018338=Carbonic anhydrase, alpha-class, conserved site, IPR023561=Carbonic anhydrase, alpha-class" CG5379 16-Dec-15 2015_12 "ENSDARG00000043589(LOC100330944),ENSDARG00000044512(LOC100333339)" WBGene00000283(cah-5) "ENSMUSG00000079715,ENSMUSG00000028463(Car9)" viable FBgn0016668 Hrp70 Hrp70 http://flybase.net/reports/FBgn0016668.html gene 0003697=single-stranded DNA binding "0005730=nucleolus, 0005634=nucleus" hrp70 16-Dec-15 2015_12 FBgn0019690 l(3)69Ai lethal (3) 69Ai http://flybase.net/reports/FBgn0019690.html gene l(3)69Ab 16-Dec-15 2015_12 lethal FBgn0265747 CR44554 http://flybase.net/reports/FBgn0265747.html non_protein_coding_gene lincRNA.531 CR44554 16-Dec-15 2015_12 FBgn0022102 l(2)k07126 lethal (2) k07126 http://flybase.net/reports/FBgn0022102.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053401 5SrRNA:CR33401 5SrRNA:CR33401 http://flybase.net/reports/FBgn0053401.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33401 CR33401 16-Dec-15 2015_12 FBgn0065760 l(2)SH0479 lethal (2) SH0479 http://flybase.net/reports/FBgn0065760.html gene l(2)SH2 0479 16-Dec-15 2015_12 "lethal,recessive" FBgn0036150 Ir68a Ionotropic receptor 68a http://flybase.net/reports/FBgn0036150.html protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity" 0009593=detection of chemical stimulus "0016020=membrane, 0016021=integral component of membrane" "CG6185, CT19410, IR68a, DmelIR68a, ionotropic receptor 68a" IPR001320=Ionotropic glutamate receptor CG6185 16-Dec-15 2015_12 "viable,fertile" FBgn0260292 GSd436 http://flybase.net/reports/FBgn0260292.html gene 16-Dec-15 2015_12 lethal FBgn0265206 T:Mito-CG9393 Mitochondrial outer membrane targeting sequence of CG9393 http://flybase.net/reports/FBgn0265206.html engineered_tag 16-Dec-15 2015_12 FBgn0032870 CG2608 http://flybase.net/reports/FBgn0032870.html protein_coding_gene 0003676=nucleic acid binding 38D.26 "IPR017330=Sperm-associated antigen 7, IPR001374=R3H domain" CG2608 16-Dec-15 2015_12 ENSDARG00000011555(spag7) ENSXETG00000017395(SPAG7) ENSMUSG00000018287(Spag7) ENSG00000091640(SPAG7) "viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0260501 Pkn::Mmus\Rtkn http://flybase.net/reports/FBgn0260501.html engineered_fusion_gene Rhot-Pkn 16-Dec-15 2015_12 FBgn0002354 l(3)87Df lethal (3) 87Df http://flybase.net/reports/FBgn0002354.html "FBgn0038112, FBgn0062841" protein_coding_gene "CG7620, l(3)S12, unnamed, l(3)s12, S12, BcDNA:SD27354" "IPR023242=FAM36A, IPR022533=Cox20/FAM36A" CG7620 16-Dec-15 2015_12 ENSDARG00000018800(zgc:92598) ENSXETG00000011390(FAM36A) ENSMUSG00000026500(Fam36a) ENSG00000203667(FAM36A) "viable,fertile,wild-type,lethal,recessive,cold sensitive,female sterile,partially,heat sensitive" macrochaeta FBgn0038438 Der-2 Derlin-2 http://flybase.net/reports/FBgn0038438.html protein_coding_gene "0030968=endoplasmic reticulum unfolded protein response, 0030433=ER-associated ubiquitin-dependent protein catabolic process, 0042742=defense response to bacterium" 0030176=integral component of endoplasmic reticulum membrane "derlin-2, CG14899, Derlin-2, Cg14899, Der-2, DER1" IPR007599=Derlin CG14899 16-Dec-15 2015_12 ENSDARG00000033871(derl3) YDR411C(DFM1) WBGene00020109(R151.6) ENSXETG00000009183(derl3) "ENSMUSG00000018442(Derl2),ENSMUSG00000009092(Derl3)" "ENSG00000072849(DERL2),ENSG00000099958(DERL3)" FBgn0069231 gl(2L)260-24 gl(2L)260-24 http://flybase.net/reports/FBgn0069231.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0003362 sesE stress-sensitive E http://flybase.net/reports/FBgn0003362.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,paralytic,somatic clone,behavior defective" "leg,somatic clone" FBgn0003486 spo spook http://flybase.net/reports/FBgn0003486.html FBgn0035618 protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0016491=oxidoreductase activity, 0005506=iron ion binding" "0006697=ecdysone biosynthetic process, 0048566=embryonic digestive tract development, 0055114=oxidation-reduction process, 0048477=oogenesis, 0007417=central nervous system development, 0001700=embryonic development via the syncytial blastoderm, 0008258=head involution, 0007494=midgut development, 0007391=dorsal closure, 0042335=cuticle development" "0043231=intracellular membrane-bounded organelle, 0016020=membrane, 0005783=endoplasmic reticulum" "CYP307A1, Dmspo, Cyp307a1, Spo, Spook, spook, 307a1, CG10594, CYP307A1-Dm" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG10594 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,fertile,lethal" "embryonic/larval midgut,presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval foregut,embryonic/larval hindgut,longitudinal connective,glial cell,midline glial cell,ectopic,midgut primordium,denticle belt,embryonic hindgut" FBgn0263250 CG43393 http://flybase.net/reports/FBgn0263250.html protein_coding_gene CG43393 16-Dec-15 2015_12 FBgn0038862 Usp8 Ubiquitin specific protease 8 http://flybase.net/reports/FBgn0038862.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0006511=ubiquitin-dependent protein catabolic process, 0045880=positive regulation of smoothened signaling pathway, 0016579=protein deubiquitination, 0090263=positive regulation of canonical Wnt signaling pathway, 0008587=imaginal disc-derived wing margin morphogenesis" 0005737=cytoplasm "Ubpy, Q9VDD8, usp8, CG5798, dUBPY, UBPY/USP8, UBPY ortholog, USP8, Usp8, CT18196, UbpY, UBPY" "IPR018200=Ubiquitin specific protease, conserved site, IPR001763=Rhodanese-like domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR015063=USP8 dimerisation domain, IPR028889=Ubiquitin specific protease domain" CG5798 16-Dec-15 2015_12 WBGene00008441(E01B7.1) ENSXETG00000016117(USP8) ENSMUSG00000027363(Usp8) ENSG00000138592(USP8) "visible,locomotor rhythm defective,lethal,lethal - all die before end of pupal stage,somatic clone,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein L3,wing margin bristle" FBgn0262077 JC09 http://flybase.net/reports/FBgn0262077.html gene 0072347=response to anesthetic 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0000724 fr fringed http://flybase.net/reports/FBgn0000724.html gene 16-Dec-15 2015_12 "visible,heat sensitive,viable,reduced,female semi-sterile,female sterile,poor,male sterile" "wing,dorsal row,ventral row,adult abdomen,eye,macrochaeta" FBgn0028249 l(3)93Bj lethal (3) 93Bj http://flybase.net/reports/FBgn0028249.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0039420 CG6154 http://flybase.net/reports/FBgn0039420.html protein_coding_gene 0016805=dipeptidase activity 0006508=proteolysis IPR008257=Renal dipeptidase family CG6154 16-Dec-15 2015_12 ENSDARG00000068181(zgc:153024) "ENSXETG00000019843(DPEP1),ENSXETG00000005433()" ENSMUSG00000019278(Dpep1) ENSG00000015413(DPEP1) viable FBgn0085552 CG41010 http://flybase.net/reports/FBgn0085552.html FBan0041010 protein_coding_gene 16-Dec-15 2015_12 FBgn0263747 CG43672 http://flybase.net/reports/FBgn0263747.html "FBan0033173, FBgn0053173, FBgn0030689" protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity, 0005215=transporter activity" 0006810=transport 0016021=integral component of membrane "CG8473, CG33173" "IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR026082=ABC transporter A, ABCA" CG43672 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable,visible" "chaeta,supernumerary" FBgn0032748 CG10492 http://flybase.net/reports/FBgn0032748.html FBgn0005567 protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "TuB1, B1, anon-37B-1, TU37B1, transcription unit 37B1" "IPR001878=Zinc finger, CCHC-type" CG10492 16-Dec-15 2015_12 ENSDARG00000067950(si:ch211-273d2.3) ENSMUSG00000038866(Zcchc2) "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0038575 CG7208 http://flybase.net/reports/FBgn0038575.html "FBtr0083617, FBpp0083037, FBtr0083618, FBpp0083038" protein_coding_gene CG 7208 CG7208 16-Dec-15 2015_12 viable FBgn0028916 CG33090 http://flybase.net/reports/FBgn0028916.html "FBgn0051837, FBgn0053090" protein_coding_gene "0004348=glucosylceramidase activity, 0008422=beta-glucosidase activity" "0008206=bile acid metabolic process, 0006665=sphingolipid metabolic process, 0016139=glycoside catabolic process" 0016021=integral component of membrane "CG7469, CG31837, CG15287, Glucosylceramidase, BG:DS01068.2" "IPR008928=Six-hairpin glycosidase-like, IPR024462=Beta-glucosidase, GBA2 type, N-terminal, IPR006775=Glucosylceramidase" CG33090 16-Dec-15 2015_12 ENSDARG00000061472(gba2) WBGene00013670(Y105E8A.10) ENSMUSG00000028467(Gba2) ENSG00000070610(GBA2) "viable,fertile,male" FBgn0041736 l(3)63Eg lethal (3) 63Eg http://flybase.net/reports/FBgn0041736.html gene group III 16-Dec-15 2015_12 lethal FBgn0037703 JHDM2 JmjC domain-containing histone demethylase 2 http://flybase.net/reports/FBgn0037703.html FBgn0067621 protein_coding_gene "0032452=histone demethylase activity, 0032454=histone demethylase activity (H3-K9 specific)" "0033169=histone H3-K9 demethylation, 2001020=regulation of response to DNA damage stimulus, 0016577=histone demethylation, 0031937=positive regulation of chromatin silencing" "0005634=nucleus, 0000785=chromatin" "CG8165, CG31123" IPR003347=JmjC domain CG8165 16-Dec-15 2015_12 ENSDARG00000062267 "ENSXETG00000006700(KDM3B),ENSXETG00000017975(KDM3A),ENSXETG00000007684(JMJD1C)" "ENSMUSG00000053470(Kdm3a),ENSMUSG00000038773(Kdm3b)" "ENSG00000115548(KDM3A),ENSG00000120733(KDM3B),ENSG00000171988(JMJD1C)" "viable,fertile" FBgn0038279 Sdr Secreted decoy of InR http://flybase.net/reports/FBgn0038279.html protein_coding_gene "0005520=insulin-like growth factor binding, 0005524=ATP binding, 0004714=transmembrane receptor protein tyrosine kinase activity" "0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0006468=protein phosphorylation, 0042594=response to starvation, 0040015=negative regulation of multicellular organism growth" "0005615=extracellular space, 0016020=membrane" "secreted decoy of InR, CG3837" "IPR006211=Furin-like cysteine-rich domain, IPR003961=Fibronectin type III, IPR013783=Immunoglobulin-like fold, IPR000494=Receptor L-domain" CG3837 16-Dec-15 2015_12 "large body,size defective,decreased cell size,viable,increased cell size,increased cell number,visible" "trichogen cell,mesothoracic tergum" FBgn0050267 CR30267 http://flybase.net/reports/FBgn0050267.html FBgn0064993 non_protein_coding_gene "CG30267, BcDNA:AT28638" CR30267 16-Dec-15 2015_12 FBgn0033867 Cpr50Ca Cuticular protein 50Ca http://flybase.net/reports/FBgn0033867.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG13338 "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG13338 16-Dec-15 2015_12 viable FBgn0263562 mir-4948 mir-4948 stem loop http://flybase.net/reports/FBgn0263562.html miRNA_gene "CR43547, dme-mir-4948" CR43547 16-Dec-15 2015_12 FBgn0011099 l(1)Q59 lethal (1) Q59 http://flybase.net/reports/FBgn0011099.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0003305 raised-wing raised wing http://flybase.net/reports/FBgn0003305.html gene rw 16-Dec-15 2015_12 "viable,reduced" wing FBgn0022321 l(1)B6.1 lethal (1) B6.1 http://flybase.net/reports/FBgn0022321.html gene B6.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0032793 CG10189 http://flybase.net/reports/FBgn0032793.html protein_coding_gene 0000049=tRNA binding "0034227=tRNA thio-modification, 0002098=tRNA wobble uridine modification" 0005829=cytosol "i180, i199" IPR019407=Cytoplasmic tRNA 2-thiolation protein 2 CG10189 16-Dec-15 2015_12 ENSDARG00000051851(ctu2) YNL119W(NCS2) WBGene00009256(tut-2) ENSXETG00000011252(TGas114e15.1) ENSG00000174177(CTU2) "viable,fertile" FBgn0000001 4.5SRNA 4.5SRNA http://flybase.net/reports/FBgn0000001.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0025683 CG3164 http://flybase.net/reports/FBgn0025683.html FBgn0031221 protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0043190=ATP-binding cassette (ABC) transporter complex "CK02656, BEST:CK02656" "IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG3164 16-Dec-15 2015_12 ENSXETG00000021581(ABCG4) "viable,partially lethal - majority die" FBgn0039199 CG13615 http://flybase.net/reports/FBgn0039199.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG13615 16-Dec-15 2015_12 viable DRSC24018 K -0.438474938 -0.297190115 -0.408138967 -0.275194658 2.451486296 -0.102750772 FBgn0027622 297\pol pol http://flybase.net/reports/FBgn0027622.html transposable_element_gene "0004190=aspartic-type endopeptidase activity, 0003676=nucleic acid binding" "0006508=proteolysis, 0015074=DNA integration" pol "IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain, IPR012337=Ribonuclease H-like domain, IPR001584=Integrase, catalytic core, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0035213 CG2199 http://flybase.net/reports/FBgn0035213.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG2199 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0013526 l(2)23AB4 lethal (2) 23AB4 http://flybase.net/reports/FBgn0013526.html gene l(2)23Af 16-Dec-15 2015_12 "lethal,recessive" FBgn0259463 C442 http://flybase.net/reports/FBgn0259463.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0050049 CG30049 http://flybase.net/reports/FBgn0050049.html protein_coding_gene CG30049-PA IPR007484=Peptidase M28 CG30049 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable DRSC21345 I 0.419832993 -1.923645196 0.164386021 1.429592861 0.038733218 -0.622010035 FBgn0046630 anon-38E.6 anon-38E.6 http://flybase.net/reports/FBgn0046630.html gene 38E.6 16-Dec-15 2015_12 FBgn0066341 mirta mirta http://flybase.net/reports/FBgn0066341.html gene "0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 memory defective FBgn0002648 mar metaphase arrest http://flybase.net/reports/FBgn0002648.html gene 0007067=mitotic nuclear division metaphasic arrest 16-Dec-15 2015_12 "lethal,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028569 robl37BC robl37BC http://flybase.net/reports/FBgn0028569.html FBgn0032739 protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex "CG15171, Robl37BC" IPR004942=Roadblock/LAMTOR2 domain CG15171 16-Dec-15 2015_12 viable FBgn0015350 CG10349 http://flybase.net/reports/FBgn0015350.html protein_coding_gene "anon-89Ea, candidate gene 5, domain II, CT29078, II, CG-CG10349" 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0065594 l(2)SH0895 lethal (2) SH0895 http://flybase.net/reports/FBgn0065594.html gene l(2)SH2 0895 16-Dec-15 2015_12 "lethal,recessive" FBgn0060854 l(3)S048319 lethal (3) S048319 http://flybase.net/reports/FBgn0060854.html gene 0483/19 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0025147 ms(2)A9 ms(2)A9 http://flybase.net/reports/FBgn0025147.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0016698 Ptpa Phosphotyrosyl phosphatase activator http://flybase.net/reports/FBgn0016698.html protein_coding_gene 0008160=protein tyrosine phosphatase activator activity 0050790=regulation of catalytic activity "unnamed, PTPA, CG3289, DPTPA" "IPR004327=Phosphotyrosyl phosphatase activator, PTPA" CG3289 16-Dec-15 2015_12 ENSDARG00000031985 YIL153W(RRD1) WBGene00022185(Y71H2AM.20) ENSXETG00000018970(PPP2R4) ENSMUSG00000039515(Ppp2r4) ENSG00000119383(PPP2R4) "viable,planar polarity defective" FBgn0035638 Tektin-C Tektin C http://flybase.net/reports/FBgn0035638.html protein_coding_gene 0008017=microtubule binding 0007017=microtubule-based process 0005875=microtubule associated complex "CG10541, Tektin-C, TEKTIN C" IPR000435=Tektin CG10541 16-Dec-15 2015_12 ENSDARG00000018605(zgc:101797) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC09741 EK -0.80103823 -0.161306532 1.067311886 -3.731354252 1.74754327 0.915708564 FBgn0262524 ver verrocchio http://flybase.net/reports/FBgn0262524.html "FBgn0027937, FBgn0086699, FBgn0036297, FBgn0046345, FBgn0060312, FBgn0046347, FBgn0046346" protein_coding_gene "0000723=telomere maintenance, 0022008=neurogenesis, 0016233=telomere capping" "0035012=polytene chromosome, telomeric region" "1479/10, CG14121, anon-WO0172774.86, l(3)S147910, anon-WO0172774.89, anon-WO0172774.87, Verrocchio, Ver, lethal (3) S147910" "IPR012340=Nucleic acid-binding, OB-fold" CG14121 16-Dec-15 2015_12 FBgn0086324 JR8 http://flybase.net/reports/FBgn0086324.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0003983 Vm34Ca Vitelline membrane 34Ca http://flybase.net/reports/FBgn0003983.html protein_coding_gene 0008316=structural constituent of vitelline membrane 0007305=vitelline membrane formation involved in chorion-containing eggshell formation "VM26A.1, VM34C.1, Vm34Cc, Vm34C, VM34C, CG9271" IPR013135=Vitelline membrane cysteine-rich domain CG9271 16-Dec-15 2015_12 oogenesis stage | stage S8-10 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0082675 E(fu) Enhancer of fused http://flybase.net/reports/FBgn0082675.html gene "0001736=establishment of planar polarity, 0007224=smoothened signaling pathway" 16-Dec-15 2015_12 FBgn0039622 eIF4E-6 eIF4E-6 http://flybase.net/reports/FBgn0039622.html FBgn0062426 protein_coding_gene "0000339=RNA cap binding, 0030371=translation repressor activity, 0031370=eukaryotic initiation factor 4G binding, 0003743=translation initiation factor activity, 0000340=RNA 7-methylguanosine cap binding" "0006413=translational initiation, 0017148=negative regulation of translation" "0016281=eukaryotic translation initiation factor 4F complex, 0005737=cytoplasm" "BcDNA:RH55324, eIF4E, CG1442" "IPR019770=Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, IPR001040=Translation Initiation factor eIF- 4e, IPR023398=Translation Initiation factor eIF- 4e-like" CG1442 16-Dec-15 2015_12 YOL139C(CDC33) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0051139 CG31139 http://flybase.net/reports/FBgn0051139.html "FBgn0039021, FBgn0065022" protein_coding_gene "partner of rumi, BcDNA:AT07872, CG17138" IPR006598=Lipopolysaccharide-modifying protein CG31139 16-Dec-15 2015_12 ENSDARG00000053463(zgc:123318) ENSXETG00000014465(KDELC2) FBgn0261461 RhoGAP18B Rho GTPase activating protein at 18B http://flybase.net/reports/FBgn0261461.html "FBgn0065041, FBgn0259169, FBgn0030986, FBgn0030988, FBgn0040888, FBgn0030987" protein_coding_gene 0005096=GTPase activator activity "0007015=actin filament organization, 0043547=positive regulation of GTPase activity, 0035095=behavioral response to nicotine, 0048149=behavioral response to ethanol" "whir, RhoGAP18B, white rabbit, 5-131, CG42274, CG7531, CG7502, CG17015, CG7481" "IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG42274 16-Dec-15 2015_12 FBgn0036052 CG10809 http://flybase.net/reports/FBgn0036052.html protein_coding_gene "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG10809 16-Dec-15 2015_12 ENSDARG00000055743(ankrd54) ENSMUSG00000033055(Ankrd54) ENSG00000100124(ANKRD54) "viable,fertile" FBgn0017433 anon-4Ba anon-4Ba http://flybase.net/reports/FBgn0017433.html gene Gene A 16-Dec-15 2015_12 FBgn0069424 JJF025 JJF025 http://flybase.net/reports/FBgn0069424.html gene 16-Dec-15 2015_12 stress response defective FBgn0263708 CR43660 http://flybase.net/reports/FBgn0263708.html non_protein_coding_gene lincRNA.336 CR43660 16-Dec-15 2015_12 FBgn0029819 Usp30 Ubiquitin specific protease 30 http://flybase.net/reports/FBgn0029819.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0016579=protein deubiquitination, 0006511=ubiquitin-dependent protein catabolic process, 1901562=response to paraquat" "Q9W462, Ubiquitin specific peptidase 30, dUSP30, CG3016, USP30, Usp30" "IPR018200=Ubiquitin specific protease, conserved site, IPR028889=Ubiquitin specific protease domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG3016 16-Dec-15 2015_12 ENSDARG00000056842(usp30) WBGene00022052(Y67D2.2) ENSXETG00000022301(usp30) ENSMUSG00000029592(Usp30) ENSG00000135093(USP30) "locomotor behavior defective,short lived,viable" FBgn0005685 cob cobblestone http://flybase.net/reports/FBgn0005685.html gene 0048749=compound eye development 16-Dec-15 2015_12 "visible,recessive" "eye,ommatidium,eye photoreceptor cell" FBgn0031961 CG7102 http://flybase.net/reports/FBgn0031961.html FBgn0031963 protein_coding_gene 0005515=protein binding 0000387=spliceosomal snRNP assembly 0071013=catalytic step 2 spliceosome CG17973 "IPR011705=BTB/Kelch-associated, IPR006571=TLDc domain, IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG7102 16-Dec-15 2015_12 viable DRSC03007 K -0.330952588 -0.370821336 -0.482054164 -0.382802781 -1.888000227 -0.290695145 FBgn0039028 CG13840 http://flybase.net/reports/FBgn0039028.html protein_coding_gene CG13840 16-Dec-15 2015_12 FBgn0028398 Taf10 TBP-associated factor 10 http://flybase.net/reports/FBgn0028398.html FBgn0062976 protein_coding_gene 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly 0006367=transcription initiation from RNA polymerase II promoter "0005669=transcription factor TFIID complex, 0000123=histone acetyltransferase complex, 0005737=cytoplasm, 0005634=nucleus" "TafII24, dmTAF10, TBP-associated factor 24kD, BcDNA:RE73934, TAF[[II]]24, taf24, TFIID, dTAF10, TAF, CG2859, dTAF[[II]]24, dTAFII24, TBP-associated factor, Taf24, dmTaf10, TAF10, TAF[[II]], dtafII24" "IPR003923=Transcription initiation factor TFIID, 23-30kDa subunit" CG2859 16-Dec-15 2015_12 YDR167W(TAF10) WBGene00006392(taf-10) ENSG00000166337(TAF10) "planar polarity defective,partially lethal - majority die,some die during pupal stage" DRSC30091 K 0.664342779 1.806765162 FBgn0014185 gyn-2 gyn-2 http://flybase.net/reports/FBgn0014185.html gene "unnamed, gynogenetic-2" 16-Dec-15 2015_12 FBgn0267555 CR45895 http://flybase.net/reports/FBgn0267555.html non_protein_coding_gene CR45895 16-Dec-15 2015_12 FBgn0267006 CR45450 http://flybase.net/reports/FBgn0267006.html non_protein_coding_gene CR45450 16-Dec-15 2015_12 FBgn0260098 2L2218 http://flybase.net/reports/FBgn0260098.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0005192 l(2)S55 lethal of Seto 55 http://flybase.net/reports/FBgn0005192.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060992 l(3)S027342b lethal (3) S027342b http://flybase.net/reports/FBgn0060992.html gene 0273/42 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0027496 ëµCOP Coat Protein (coatomer) ëµ http://flybase.net/reports/FBgn0027496.html protein_coding_gene 0005198=structural molecule activity "0006890=retrograde vesicle-mediated transport, Golgi to ER" "0005875=microtubule associated complex, 0030126=COPI vesicle coat" "CG9543, epsilon-COP, epsilonCOP, bcDNA:LD29885, epsilon-Cop, COPI epsilon subunit, BcDNA:LD29885" "IPR011990=Tetratricopeptide-like helical domain, IPR006822=Coatomer, epsilon subunit" CG9543 16-Dec-15 2015_12 ENSDARG00000018562(zgc:103652) WBGene00009732(F45G2.4) ENSXETG00000010134(COPE) ENSMUSG00000055681(Cope) ENSG00000105669(COPE) viable FBgn0002858 Mst51F Male-specific RNA 51F http://flybase.net/reports/FBgn0002858.html gene "mst(2)ag-35, mst-35" 16-Dec-15 2015_12 FBgn0025004 E(var)3-101 E(var)3-101 http://flybase.net/reports/FBgn0025004.html gene E-(3)1[01] 16-Dec-15 2015_12 FBgn0031990 PAPLA1 Phosphatidic Acid Phospholipase A1 http://flybase.net/reports/FBgn0031990.html FBgn0031989 protein_coding_gene "0004620=phospholipase activity, 0008970=phosphatidylcholine 1-acylhydrolase activity, 0046872=metal ion binding" "0007283=spermatogenesis, 0016063=rhodopsin biosynthetic process, 0006888=ER to Golgi vesicle-mediated transport" "0005654=nucleoplasm, 0030134=ER to Golgi transport vesicle, 0005737=cytoplasm" "Sec23-IP, phosphatidic acid phospholipase A1, CG14278, Sec23-interacting protein, Phosphatidic acid phospholipase A1, CG8552" "IPR004177=DDHD domain, IPR004170=WWE domain" CG8552 16-Dec-15 2015_12 "ENSXETG00000015184(),ENSXETG00000010238(SEC23IP)" "ENSMUSG00000055319(Sec23ip),ENSMUSG00000061313" "viable,fertile" FBgn0084797 G56 G56 http://flybase.net/reports/FBgn0084797.html gene 16-Dec-15 2015_12 FBgn0062636 EP995 EP995 http://flybase.net/reports/FBgn0062636.html gene EP(3)0995 16-Dec-15 2015_12 FBgn0260431 CG42526 http://flybase.net/reports/FBgn0260431.html protein_coding_gene IPR006578=MADF domain CG42526 16-Dec-15 2015_12 FBgn0032213 CG5390 http://flybase.net/reports/FBgn0032213.html FBgn0043834 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "SPH, BEST:GH06341, SPH35, c-SPH35, gh06341, serine protease homologue protein" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG5390 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" viable FBgn0266157 CR44863 http://flybase.net/reports/FBgn0266157.html non_protein_coding_gene CR44863 16-Dec-15 2015_12 FBgn0023508 Ocrl Oculocerebrorenal syndrome of Lowe http://flybase.net/reports/FBgn0023508.html protein_coding_gene "0004445=inositol-polyphosphate 5-phosphatase activity, 0034593=phosphatidylinositol bisphosphate phosphatase activity, 0005096=GTPase activator activity" "0006897=endocytosis, 0032187=actomyosin contractile ring localization, 2000431=regulation of cytokinesis, actomyosin contractile ring assembly, 0000281=mitotic cytokinesis, 0043087=regulation of GTPase activity, 0046856=phosphatidylinositol dephosphorylation" "0005737=cytoplasm, 0005770=late endosome, 0055037=recycling endosome, 0005769=early endosome" "EG:86E4.5, inositol 5-phosphatase, CG3573, inositol polyphosphate 5-phosphatase, Oculocerebrorenal syndrome of Lowe ortholog (H. sapiens), Oculocerebrorenal syndrome of Lowe 1 ortholog, dOCRL, ocrl" "IPR008936=Rho GTPase activation protein, IPR000300=Inositol polyphosphate-related phosphatase, IPR005135=Endonuclease/exonuclease/phosphatase, IPR000198=Rho GTPase-activating protein domain" CG3573 16-Dec-15 2015_12 "ENSDARG00000060541(ocrl),ENSDARG00000042111(LOC563543)" WBGene00007620(ocrl-1) ENSXETG00000014435(INPP5B) "ENSMUSG00000028894(Inpp5b),ENSMUSG00000001173(Ocrl)" "ENSG00000204084(INPP5B),ENSG00000122126(OCRL)" "viable,fertile,visible" "chaeta,supernumerary" FBgn0026430 Grip84 Gamma-tubulin ring protein 84 http://flybase.net/reports/FBgn0026430.html protein_coding_gene "0043015=gamma-tubulin binding, 0051011=microtubule minus-end binding, 0008017=microtubule binding, 0015631=tubulin binding" "0007020=microtubule nucleation, 0007017=microtubule-based process, 0051297=centrosome organization, 0007283=spermatogenesis, 0007126=meiotic nuclear division, 0051726=regulation of cell cycle, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0030953=astral microtubule organization, 0051225=spindle assembly" "0072686=mitotic spindle, 0005813=centrosome, 0005875=microtubule associated complex, 0008275=gamma-tubulin small complex, 0000922=spindle pole" "Dgrips84, l(1)[[t]]PG36, l(1)[[t]]PG66, CG3917, GCP2, Dgrip84, DGrip84, grip84, gamma-tubulin ring protein 84" IPR007259=Gamma-tubulin complex component protein CG3917 16-Dec-15 2015_12 ENSDARG00000013079(tubgcp2) ENSXETG00000000787(TUBGCP2) ENSMUSG00000025474(Tubgcp2) ENSG00000130640(TUBGCP2) embryonic stage "lethal,recessive,mitotic cell cycle defective,partially lethal - majority die,male sterile,meiotic cell cycle defective,viable,visible" "chromosome & procephalic neuroblast | third instar larval stage,spindle & procephalic neuroblast | third instar larval stage,pericentriolar material & procephalic neuroblast | third instar larval stage,macrochaeta & thorax,cuticle & abdomen,nucleus & onion stage spermatid,Nebenkern & onion stage spermatid,nucleus & onion stage spermatid | supernumerary,Nebenkern & onion stage spermatid | supernumerary,pericentriolar material & primary spermatocyte,spindle & primary spermatocyte,aster & primary spermatocyte,trichogen cell" DRSC20248 I 3.925465832 -0.200243084 0.222298365 -0.035259642 -0.087225277 0.584048881 FBgn0261956 baz::par-6 http://flybase.net/reports/FBgn0261956.html engineered_fusion_gene 16-Dec-15 2015_12 lethal "follicle cell,somatic clone" FBgn0053080 CG33080 http://flybase.net/reports/FBgn0053080.html "FBgn0029792, FBgn0029793, FBgn0040915" protein_coding_gene "0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process 0017177=glucosidase II complex "CG15775, CG3141, CG15774" "IPR000322=Glycoside hydrolase family 31, IPR013785=Aldolase-type TIM barrel, IPR017853=Glycoside hydrolase superfamily" CG33080 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable" DRSC18285 I -1.507725032 0.564026369 -0.384340044 0.090007679 0.24180156 -0.663448441 FBgn0011118 l(1)Q79 lethal (1) Q79 http://flybase.net/reports/FBgn0011118.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0003544 stw straw http://flybase.net/reports/FBgn0003544.html gene "str, Stonewall" 16-Dec-15 2015_12 "visible,recessive,body color defective,viable,poor,semidominant" "wing,macrochaeta,microchaeta" FBgn0005196 l(3)36d10 lethal (3) 36d10 http://flybase.net/reports/FBgn0005196.html gene 16-Dec-15 2015_12 lethal FBgn0265688 CR44495 http://flybase.net/reports/FBgn0265688.html non_protein_coding_gene CR44495 16-Dec-15 2015_12 FBgn0065962 l(2)SH0030 lethal (2) SH0030 http://flybase.net/reports/FBgn0065962.html gene l(2)SH2 0030 16-Dec-15 2015_12 "lethal,recessive" FBgn0028109 l(3)S068911 lethal (3) S068911 http://flybase.net/reports/FBgn0028109.html gene 0689/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0031413 CG9967 http://flybase.net/reports/FBgn0031413.html protein_coding_gene CG9967 16-Dec-15 2015_12 ENSMUSG00000068011(2510049J12Rik) viable FBgn0026880 E(Ubx)3L E(Ubx)3L http://flybase.net/reports/FBgn0026880.html gene 16-Dec-15 2015_12 FBgn0260438 rad201 radiation-resistant 201 http://flybase.net/reports/FBgn0260438.html FBgn0003194 protein_coding_gene "rad(2)201, rad(2)201[G1], radiation-resistant" 16-Dec-15 2015_12 "viable,chemical sensitive,radiation sensitive" "egg chamber,oocyte,egg" FBgn0038892 CG15498 http://flybase.net/reports/FBgn0038892.html protein_coding_gene CG15498 16-Dec-15 2015_12 ENSDARG00000018281(zgc:110373) ENSXETG00000012978(C15orf26) ENSMUSG00000011154(1700026D08Rik) ENSG00000156206(C15orf26) viable FBgn0032533 CG16888 http://flybase.net/reports/FBgn0032533.html protein_coding_gene CG16888 16-Dec-15 2015_12 viable FBgn0264837 CR44045 http://flybase.net/reports/FBgn0264837.html non_protein_coding_gene CR44045 16-Dec-15 2015_12 FBgn0052846 CG32846 http://flybase.net/reports/FBgn0052846.html protein_coding_gene CG32846 16-Dec-15 2015_12 FBgn0029909 CG12796 http://flybase.net/reports/FBgn0029909.html protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0004930=G-protein coupled receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG12796 16-Dec-15 2015_12 viable FBgn0058158 CG40158 http://flybase.net/reports/FBgn0058158.html FBan0040158 protein_coding_gene 16-Dec-15 2015_12 FBgn0266818 CR45280 http://flybase.net/reports/FBgn0266818.html non_protein_coding_gene CR45280 16-Dec-15 2015_12 FBgn0069301 XRCC4 XRCC4 http://flybase.net/reports/FBgn0069301.html gene 0005515=protein binding 16-Dec-15 2015_12 FBgn0085551 CG40995 http://flybase.net/reports/FBgn0085551.html FBan0040995 protein_coding_gene 16-Dec-15 2015_12 FBgn0060547 l(3)S098614 lethal (3) S098614 http://flybase.net/reports/FBgn0060547.html gene 0986/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0266806 CR45268 http://flybase.net/reports/FBgn0266806.html non_protein_coding_gene CR45268 16-Dec-15 2015_12 FBgn0004984 blu blunt http://flybase.net/reports/FBgn0004984.html gene 16-Dec-15 2015_12 "visible,recessive" wing FBgn0038330 CG14868 http://flybase.net/reports/FBgn0038330.html protein_coding_gene IPR019179=Coiled-coil domain-containing protein 149-A CG14868 16-Dec-15 2015_12 ENSDARG00000020857(ccdc149) WBGene00009258(F29G6.2) ENSXETG00000002121() ENSMUSG00000051719 ENSG00000181982(CCDC149) DRSC14991 I 1.010259923 1.533437542 0.94208393 0.962579695 -0.118877228 0.478200638 FBgn0002797 ms(1)7 male sterile (1) 7 http://flybase.net/reports/FBgn0002797.html gene 16-Dec-15 2015_12 "male sterile,female fertile,viable" FBgn0259564 B0578 http://flybase.net/reports/FBgn0259564.html gene 16-Dec-15 2015_12 FBgn0025827 CG6421 http://flybase.net/reports/FBgn0025827.html FBgn0034163 protein_coding_gene 0003796=lysozyme activity EG:EG0003.8 "IPR008597=Destabilase, IPR023346=Lysozyme-like domain" CG6421 16-Dec-15 2015_12 "WBGene00017691(ilys-5),WBGene00016670(ilys-3),WBGene00016669(ilys-2),WBGene00016668(ilys-1),WBGene00016958(ilys-4)" viable FBgn0017376 l(1)HM452 lethal (1) HM452 http://flybase.net/reports/FBgn0017376.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038123 CG8508 http://flybase.net/reports/FBgn0038123.html FBgn0044656 protein_coding_gene anon-WO0140519.216 CG8508 16-Dec-15 2015_12 viable FBgn0004522 l(4)102CDf lethal (4) 102CDf http://flybase.net/reports/FBgn0004522.html gene "l(4)7, l(4)CDf" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0013295 M(2)OE227 M(2)OE227 http://flybase.net/reports/FBgn0013295.html gene 16-Dec-15 2015_12 FBgn0001468 l(1)8 lethal (1) 8 http://flybase.net/reports/FBgn0001468.html gene tsl(1)8 16-Dec-15 2015_12 "male sterile,heat sensitive,lethal,male" "spermatid,primary spermatocyte cyst,spermatocyte" FBgn0264565 CR43937 http://flybase.net/reports/FBgn0264565.html non_protein_coding_gene CR43937 16-Dec-15 2015_12 FBgn0039801 Npc2h Niemann-Pick type C-2h http://flybase.net/reports/FBgn0039801.html "FBgn0047050, FBgn0061369, FBgn0062497" protein_coding_gene "0001530=lipopolysaccharide binding, 0030882=lipid antigen binding, 0042834=peptidoglycan binding, 0070891=lipoteichoic acid binding, 0032934=sterol binding" "0015918=sterol transport, 0042381=hemolymph coagulation" "0005576=extracellular region, 0005615=extracellular space" "npc2h, BcDNA:RH68460, DmML1A, BcDNA:RH04252, BcDNA:GH26608, CG11315" "IPR003172=MD-2-related lipid-recognition domain, IPR014756=Immunoglobulin E-set" CG11315 16-Dec-15 2015_12 viable FBgn0036660 CG13025 http://flybase.net/reports/FBgn0036660.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination 0005634=nucleus "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001841=Zinc finger, RING-type, IPR001680=WD40 repeat" CG13025 16-Dec-15 2015_12 ENSXETG00000007674(RFWD3) ENSMUSG00000033596(Rfwd3) ENSG00000168411(RFWD3) "viable,fertile" FBgn0053728 snmRNA:430:CR33728 snmRNA:430:CR33728 http://flybase.net/reports/FBgn0053728.html non_protein_coding_gene CR33728 CR33728 16-Dec-15 2015_12 FBgn0063374 snoRNA:snR38:54Eb snoRNA:snR38:54Eb http://flybase.net/reports/FBgn0063374.html snoRNA_gene "Snr38snoRNA, CR32896" CR32896 16-Dec-15 2015_12 FBgn0039711 CG7824 http://flybase.net/reports/FBgn0039711.html protein_coding_gene CG7824 16-Dec-15 2015_12 viable FBgn0265452 CR44352 http://flybase.net/reports/FBgn0265452.html non_protein_coding_gene lincRNA.83 CR44352 16-Dec-15 2015_12 FBgn0002420 l(3)DTS8 lethal (3) DTS8 http://flybase.net/reports/FBgn0002420.html gene DTS-8 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,lethal - all die before end of larval stage,some die during larval stage" FBgn0015987 l(2)PC4-Q lethal (2) PC4-Q http://flybase.net/reports/FBgn0015987.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015699 E(var)8 Enhancer of variegation 8 http://flybase.net/reports/FBgn0015699.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0035415 CG14966 http://flybase.net/reports/FBgn0035415.html protein_coding_gene IPR003746=Protein of unknown function DUF167 CG14966 16-Dec-15 2015_12 WBGene00012164(W01A8.2) ENSXETG00000006028(Q6DJ28_XENTR) ENSMUSG00000025102(3110040N11Rik) ENSG00000169609(C15orf40) viable FBgn0031878 sip2 septin interacting protein 2 http://flybase.net/reports/FBgn0031878.html protein_coding_gene 0005515=protein binding CG9188 CG9188 16-Dec-15 2015_12 FBgn0002425 l(3)F24 lethal (3) F24 http://flybase.net/reports/FBgn0002425.html gene l(3)24 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone,wing hair" FBgn0004492 DhpO Dihydropterin oxidase http://flybase.net/reports/FBgn0004492.html gene 0004154=dihydropterin oxidase activity 0051067=dihydropteridine metabolic process 16-Dec-15 2015_12 FBgn0035208 CG9184 http://flybase.net/reports/FBgn0035208.html protein_coding_gene CG9184 16-Dec-15 2015_12 viable DRSC08636 E 0.879868527 1.027657362 1.746869918 1.431078397 0.604011885 -0.022614165 FBgn0267709 CR46042 http://flybase.net/reports/FBgn0267709.html non_protein_coding_gene CR46042 16-Dec-15 2015_12 FBgn0052539 CG32539 http://flybase.net/reports/FBgn0052539.html protein_coding_gene 16-Dec-15 2015_12 FBgn0063645 CE3-1 "Calcineurin enhancer, chromosome 3, group 1" http://flybase.net/reports/FBgn0063645.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013319 Pcp25 Pupal-cuticle-protein-25kD http://flybase.net/reports/FBgn0013319.html gene 16-Dec-15 2015_12 FBgn0005068 fs(2)OW209 female sterile (2) OW209 http://flybase.net/reports/FBgn0005068.html gene 16-Dec-15 2015_12 FBgn0065510 l(2)SH1177 lethal (2) SH1177 http://flybase.net/reports/FBgn0065510.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262383 mir-284 mir-284 stem loop http://flybase.net/reports/FBgn0262383.html "FBgn0067707, FBgn0262199" miRNA_gene "dme-mir-284, mir-284, dme-miR-284, CR33600, MiR-284, CR42906, miR-284" CR42906 16-Dec-15 2015_12 "viable,visible,lethal - all die before end of larval stage,some die during larval stage" wing FBgn0069163 mcl(3)Z1641 mcl(3)Z1641 http://flybase.net/reports/FBgn0069163.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0021894 l(2)k13116 lethal (2) k13116 http://flybase.net/reports/FBgn0021894.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037550 CG9667 http://flybase.net/reports/FBgn0037550.html protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0000974=Prp19 complex, 0071011=precatalytic spliceosome" ISY1 IPR009360=Isy1-like splicing CG9667 16-Dec-15 2015_12 ENSDARG00000063629 YJR050W(ISY1) WBGene00009966(F53B7.3) ENSMUSG00000030056(Isy1) ENSG00000221812 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC16535 I -0.087595313 2.574076219 1.099386934 0.353109175 -0.334236746 0.178483692 FBgn0265101 Sgt1 suppressor-of-G2-allele-of-skp1 http://flybase.net/reports/FBgn0265101.html "FBgn0011026, FBgn0260939, FBgn0086216, FBgn0037568" protein_coding_gene "0030674=protein binding, bridging, 0051087=chaperone binding" "0051297=centrosome organization, 0007405=neuroblast proliferation, 0045201=maintenance of neuroblast polarity, 0050821=protein stabilization" "0005813=centrosome, 0032154=cleavage furrow, 0000776=kinetochore" "CG9617, lethal (3) s2383, l(3)s2383, DmSgt1, sgt1, Q9VHT3" "IPR007699=SGS domain, IPR008978=HSP20-like chaperone, IPR007052=CS domain" CG9617 16-Dec-15 2015_12 ENSDARG00000020608(LOC100333357) YOR057W(SGT1) WBGene00008371(D1054.3) ENSXETG00000018887(sugt1) ENSMUSG00000022024(Sugt1) ENSG00000165416(SUGT1) FBgn0065731 l(2)SH0553 lethal (2) SH0553 http://flybase.net/reports/FBgn0065731.html gene l(2)SH2 0553 16-Dec-15 2015_12 "lethal,recessive" FBgn0002049 l(2)37Fb lethal (2) 37Fb http://flybase.net/reports/FBgn0002049.html gene l(2)E146 16-Dec-15 2015_12 lethal FBgn0261738 EC3322 http://flybase.net/reports/FBgn0261738.html gene 16-Dec-15 2015_12 female sterile FBgn0033945 CG12868 http://flybase.net/reports/FBgn0033945.html protein_coding_gene CT32008 CG12868 16-Dec-15 2015_12 viable FBgn0028665 VhaAC39-1 Vacuolar H+ ATPase AC39 subunit 1 http://flybase.net/reports/FBgn0028665.html "FBgn0025327, FBgn0029680" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" "0015991=ATP hydrolysis coupled proton transport, 0007035=vacuolar acidification, 0008593=regulation of Notch signaling pathway, 0015992=proton transport" "0000220=vacuolar proton-transporting V-type ATPase, V0 domain, 0033181=plasma membrane proton-transporting V-type ATPase complex, 0005886=plasma membrane" "CG2934, vhaAC39-1, Vacuolar H[+] ATPase subunit AC39-1, V-ATPase V0 d subunit, anon-EST:GressD5, VhaAC39, ATP6V0D1, Vhaac39, Vacuolar H[+]-ATPase C39 subunit, vhaAC39, vacuolar ATPsintase subunit 1" "IPR016727=ATPase, V0 complex, subunit d, IPR002843=ATPase, V0 complex, c/d subunit" CG2934 16-Dec-15 2015_12 ENSDARG00000069090(atp6v0d1) YLR447C(VMA6) WBGene00016258(vha-16) ENSXETG00000004705(ATP6V0D1) ENSMUSG00000013160(Atp6v0d1) ENSG00000159720(ATP6V0D1) "viable,fertile,lethal" "follicle cell,somatic clone" FBgn0062517 CG16984 http://flybase.net/reports/FBgn0062517.html FBgn0035354 protein_coding_gene BcDNA:AT01695 "IPR026150=Enkurin, IPR027012=Enkurin domain" CG16984 16-Dec-15 2015_12 ENSDARG00000031248(enkur) ENSXETG00000018842(ENKUR) ENSMUSG00000026679(Enkur) ENSG00000151023(ENKUR) FBgn0260805 EP3-612 http://flybase.net/reports/FBgn0260805.html gene 16-Dec-15 2015_12 FBgn0000515 dvw divergent wings http://flybase.net/reports/FBgn0000515.html gene 16-Dec-15 2015_12 "visible,male,wild-type,female,male limited,recessive" "wing,macrochaeta" FBgn0065225 l(2)SH2211 lethal (2) SH2211 http://flybase.net/reports/FBgn0065225.html gene l(2)SH2 2211 16-Dec-15 2015_12 "lethal,recessive" FBgn0024598 spi::vn spi::vn http://flybase.net/reports/FBgn0024598.html engineered_fusion_gene VN::SPI 16-Dec-15 2015_12 "visible,lethal" "wing vein,ectopic,eye,border follicle cell,somatic clone" FBgn0024677 l(1)LefEM7 lethal (1) LefEM7 http://flybase.net/reports/FBgn0024677.html gene EM7 16-Dec-15 2015_12 FBgn0263232 Nxf3 Nuclear export factor 3 http://flybase.net/reports/FBgn0263232.html "FBgn0052135, FBgn0061490" protein_coding_gene 0006406=mRNA export from nucleus 0005622=intracellular "nuclear export factor 3, NXF3, nxf3, CG32135" "IPR018222=Nuclear transport factor 2, eukaryote, IPR002075=Nuclear transport factor 2, IPR001611=Leucine-rich repeat, IPR030217=Nuclear RNA export factor" CG32135 16-Dec-15 2015_12 FBgn0001635 l(1)dn15 lethal (1) discs normal 15 http://flybase.net/reports/FBgn0001635.html gene "l(1)d norm-15, l(1)d.norm.-15" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0022364 Pt-8 Larval protein-8 http://flybase.net/reports/FBgn0022364.html gene 16-Dec-15 2015_12 FBgn0040370 CG13375 http://flybase.net/reports/FBgn0040370.html FBgn0029519 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0007264=small GTPase mediated signal transduction 0016020=membrane EG:BACR37P7.8 "IPR020849=Small GTPase superfamily, Ras type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain" CG13375 16-Dec-15 2015_12 "ENSDARG00000012772(zgc:153845),ENSDARG00000058464(zgc:152698)" "ENSXETG00000019483(),ENSXETG00000010347(TGas140j17.1)" viable FBgn0004009 wg wingless http://flybase.net/reports/FBgn0004009.html "FBgn0001109, FBgn0003467, FBgn0003469, FBgn0011783" protein_coding_gene "0005112=Notch binding, 0005110=frizzled-2 binding, 0016015=morphogen activity, 0050840=extracellular matrix binding, 0005539=glycosaminoglycan binding, 0005109=frizzled binding, 0005102=receptor binding, 0005515=protein binding, 0043395=heparan sulfate proteoglycan binding" "0061382=Malpighian tubule tip cell differentiation, 0043066=negative regulation of apoptotic process, 0061332=Malpighian tubule bud morphogenesis, 0035288=anterior head segmentation, 0061320=pericardial nephrocyte differentiation, 0007223=Wnt signaling pathway, calcium modulating pathway, 0048754=branching morphogenesis of an epithelial tube, 0007346=regulation of mitotic cell cycle, 0035170=lymph gland crystal cell differentiation, 0030032=lamellipodium assembly, 0003136=negative regulation of heart induction by canonical Wnt signaling pathway, 0007447=imaginal disc pattern formation, 0035019=somatic stem cell maintenance, 0007367=segment polarity determination, 0035217=labial disc development, 0051017=actin filament bundle assembly, 0032876=negative regulation of DNA endoreduplication, 0044719=regulation of imaginal disc-derived wing size, 0048542=lymph gland development, 0007418=ventral midline development, 0007446=imaginal disc growth, 0007423=sensory organ development, 0048332=mesoderm morphogenesis, 0009798=axis specification, 0014019=neuroblast development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035277=spiracle morphogenesis, open tracheal system, 0030917=midbrain-hindbrain boundary development, 0045599=negative regulation of fat cell differentiation, 0042127=regulation of cell proliferation, 0007523=larval visceral muscle development, 0035147=branch fusion, open tracheal system, 0035224=genital disc anterior/posterior pattern formation, 0007394=dorsal closure, elongation of leading edge cells, 2000648=positive regulation of stem cell proliferation, 0060914=heart formation, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0035220=wing disc development, 0046672=positive regulation of compound eye retinal cell programmed cell death, 0030707=ovarian follicle cell development, 0009996=negative regulation of cell fate specification, 0035289=posterior head segmentation, 0007479=leg disc proximal/distal pattern formation, 0010942=positive regulation of cell death, 0035017=cuticle pattern formation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007391=dorsal closure, 0008284=positive regulation of cell proliferation, 0007419=ventral cord development, 0001745=compound eye morphogenesis, 0042326=negative regulation of phosphorylation, 0007498=mesoderm development, 0035263=genital disc sexually dimorphic development, 0045892=negative regulation of transcription, DNA-templated, 0007616=long-term memory, 0060070=canonical Wnt signaling pathway, 0035311=wing cell fate specification, 0008544=epidermis development, 0007448=anterior/posterior pattern specification, imaginal disc, 0035167=larval lymph gland hemopoiesis, 0016318=ommatidial rotation, 0035153=epithelial cell type specification, open tracheal system, 0072091=regulation of stem cell proliferation, 0061328=posterior Malpighian tubule development, 0007476=imaginal disc-derived wing morphogenesis, 0007442=hindgut morphogenesis, 0007398=ectoderm development, 0010002=cardioblast differentiation, 0007450=dorsal/ventral pattern formation, imaginal disc, 0046847=filopodium assembly, 0035290=trunk segmentation, 0048728=proboscis development, 0008595=anterior/posterior axis specification, embryo, 0051124=synaptic growth at neuromuscular junction, 0050808=synapse organization, 0035225=determination of genital disc primordium, 0035215=genital disc development, 0042691=positive regulation of crystal cell differentiation, 0048190=wing disc dorsal/ventral pattern formation, 0007444=imaginal disc development, 0007507=heart development, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0048076=regulation of compound eye pigmentation, 0016055=Wnt signaling pathway, 0045611=negative regulation of hemocyte differentiation, 0002168=instar larval development" "0005886=plasma membrane, 0005771=multivesicular body, 0005615=extracellular space, 0005770=late endosome, 0030139=endocytic vesicle, 0005783=endoplasmic reticulum, 0005769=early endosome, 0045121=membrane raft, 0043195=terminal bouton, 0009986=cell surface, 0005576=extracellular region, 0016023=cytoplasmic membrane-bounded vesicle" "spade, Wnt, l(2)02657, DWnt-1, l(2)rO727, l(2)wg, Glazed, flag, Sp, I, Dint-1, wnt, Dm Wg, Complementation group I, DWint-1, fg, wgl, dWnt, Bristled, WNT, Wingless, Wnt1, Wnt-1, WG, Sternopleural, Wg, wnt1, Wnt/Wg, Gla, Br, Dm-1, spd, CG4889, int-1" "IPR018161=Wnt protein, conserved site, IPR005817=Wnt" CG4889 16-Dec-15 2015_12 ENSDARG00000055554(wnt1) WBGene00000857(cwn-1) ENSXETG00000009817(WNT1) ENSMUSG00000036856(Wnt4) ENSG00000162552(WNT4) " embryonic stage , embryonic stage | stage 5 , embryonic stage | stage 10 , larval stage , embryonic stage | stage 9 , larval stage | third instar stage 2 , embryonic stage -- adult stage , embryonic stage | 5-8 hr , embryonic stage | stage >14 " "

segment polarity , embryonic central nervous system

, organism | 10-20% egg length

,

segmentally repeated ,

terminal , embryonic/larval foregut

, dorsal mesothoracic disc

, parasegment 8 visceral mesoderm

{ - abd-A* } , parasegment | restricted

segmentally repeated , stomodeum

, analia

, head segment

, dorsal mesothoracic disc | restricted

, parasegment 8 visceral mesoderm

{ - Ubx* } , labrum

, procephalic segment

,

80-90% egg length , ventral thoracic disc

, labral segment

, organism | 90-100% egg length

, dorsal metathoracic disc

, embryonic/larval hindgut

, parasegment 8 visceral mesoderm

{ - dpps4 } , Malpighian tubule | posterior

, proctodeum

, parasegment 8 &&of visceral mesoderm

" " embryonic stage | stage 12 , embryonic stage | mid-late , larval stage | third instar , embryonic stage | stage 9-11 , embryonic stage | stage >9 , embryonic stage | stage 10 , embryonic stage , embryonic stage | stage 11 , adult stage , larval stage | third instar stage 2 , embryonic stage | stage 8-11 , embryonic stage | stage 7-11 , adult stage | female " " visceral mesoderm &&of parasegment 8

, parasegment 8 &&of visceral mesoderm

, mesothoracic tergum | restricted & ectoderm | apical

, parasegment 8 visceral mesoderm

{ 0 Ubxhs.PU } , ventral neurogenic region && embryonic labral segment | restricted

, protocerebral neuroblast | subset

, tritocerebral neuroblast | subset

, embryonic central nervous system

, neuroblast NB5-1

, neuroblast NB5-4

, parasegment 8 visceral mesoderm

{ v Df(3R)bxd100 ] } , mesothoracic tergum | restricted & mesoderm

, germarium cap cell

, bouton | subset

, dorsal mesothoracic disc

dorsal/ventral compartment boundary , neuroblast NB5-2

, dorsal mesothoracic disc | dorsal/ventral compartment boundary

, antennal segment

, neuroblast NB5-6

, procephalic neuroblast | subset

, proctodeum | ventral

, neuroblast NB5-3

, parasegment 8 visceral mesoderm

{ 0 Ubx6.28 } , dorsal mesothoracic disc | restricted

, ventral neurogenic region && embryonic intercalary segment | restricted

, embryonic/larval digestive system

, parasegment | segmentally repeated

, head

, epidermis

,

segment polarity{ - arm* } , germline cell

, neuroblast NB5-5

, embryonic/larval foregut

, intercalary segment

, terminal filament

, ventral neurogenic region && embryonic antennal segment | restricted

, Malpighian tubule | posterior

, deuterocerebral neuroblast | subset

, labral segment

" "lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,segment polarity phenotype,size defective,hyperplasia,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,viable,female fertile,reduced,dominant,fertile,eye color defective,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,decreased cell number,increased cell size,increased cell death,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,decreased cell death,heat sensitive,increased cell number,neuroanatomy defective,cell shape defective,germline clone,mitotic cell cycle defective,neurophysiology defective,cold sensitive,endomitotic cell cycle defective,short lived,RU486 conditional" "epidermis,antenna,wing,wing disc,mesothoracic tergum,anterior & posterior dorsocentral bristle,posterior postalar bristle,anterior scutellar bristle,posterior scutellar bristle,dorsal row,ventral row,proctodeum,embryonic anal pad,adult prothoracic segment,distiproboscis,pseudotracheal sensillum,embryo,wing blade,wing margin bristle,sternopleural bristle,embryonic hindgut,genital disc,haltere,leg,female gonopod,abdominal tergite 8,female & male reproductive system,metathoracic leg,metathoracic tibia,metathoracic metatarsus,metathoracic femur,metathoracic leg sensillum,metathoracic coxa,metathoracic trochanter,eye disc,cuticle,abdomen,Malpighian tubule,eye,pigment granule,pigment cell,ommatidium,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,embryonic/first instar larval cuticle,microchaeta,abdominal ventral denticle belt,embryonic/larval dorsal vessel,cuprophilic cell,midgut interstitial cell,germarium region 1,basal stalk,ovariole,RP2 motor,RP2sib,embryonic epidermis,embryonic brain,ventral nerve cord,tergite,sternite,wing hinge,ventral thoracic disc,yellow club,retina, prothoracic leg,sex comb,labellum,lateral ocellus,frons,anal plate,interommatidial bristle,male genitalia,gonopod long bristle,gonopod thorn bristle,wing margin,embryonic head,filzkorper,midgut constriction,segment,neuroblast,stomodeal invagination,dorsal hair,secondary pigment cell,denticle,alula,humeral crossvein,sensillum campaniformium of dorsal radius,wing hinge primordium,antennal disc,head,cone cell,embryonic/larval fat body,mesoderm,embryonic stomatogastric nervous system,presumptive embryonic/larval cns,longitudinal connective,commissure,scutum,mesothoracic pleurum,midline glial cell,embryonic frontal ganglion,embryonic/larval somatic muscle,axillary sclerite,embryonic maxillary segment,inter-ommatidial cell,abdominal ventral bipolar neuron vbp,sensory organ cell,multidendritic neuron,embryonic/larval cuticle,embryonic gnathal segment, somatic muscle,embryonic/larval midgut,genital disc primordium,cardiogenic mesoderm,embryonic/larval lymph gland,cardioblast,embryonic/larval lateral trunk,embryonic/larval tracheal system,embryonic/larval dorsal branch,visceral mesoderm,embryonic leading edge cell primordium,embryonic myoblast,Keilin's organ,sensory mother cell,hindgut visceral muscle primordium,medulla neuropil,antennal sense organ,embryonic leading edge cell,ventral midline,ventral epidermis primordium,corpus cardiacum primordium,dorsal trunk primordium,embryonic/larval posterior spiracle,presumptive embryonic/larval pns,mesothoracic leg disc,visceral branch,eye-antennal disc,ocellus,morphogenetic furrow,embryonic/larval ganglionic branch,dorsal fine hair,embryonic segment,neuromuscular junction,bouton,postsynaptic membrane,tibia,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,embryonic/larval dorsal trunk,abdominal dorsal acute muscle,pericardial cell,embryonic/larval pericardial cell,dorsal neurohemal organ,macrochaeta,motor neuron,nucleus,embryonic/larval salivary gland,indirect flight muscle,proboscis,pleural wing process,mesothoracic tarsal bristle longitudinal row,double row,triple row,prothoracic unguis,maxillary palpus,trichome of posterior wing margin,tarsal segment,mesothoracic leg,sensillum coeloconicum,embryonic large intestine,labial segment,genitalia,embryonic/larval epidermis,scutellum,wing sclerite,anterior adult hindgut,embryonic/larval hindgut,NMJ bouton,embryonic/larval NMJ,lymph gland derived hemocyte,embryonic/larval lymph gland,crystal cell,abdominal segment,abdominal sternite 6-7,histoblast,scutellar bristle,prothoracic leg disc,pleurum, wing hinge sclerite,unguis,posterior lobe,ejaculatory bulb apodeme,terminalia,embryonic/larval visceral branch,visceral branch primordium,presumptive embryonic/larval digestive system,axillary pouch,pleural wing sclerite,stigmatophore,anterior postalar bristle,anterior supraalar bristle,posterior supraalar bristle,cone cell" FBgn0036590 CG13065 http://flybase.net/reports/FBgn0036590.html FBgn0047003 protein_coding_gene BcDNA:RH56745 CG13065 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC09948 E 0.468574293 0.050841571 1.727710267 -0.831450725 -0.065332039 0.04374212 FBgn0036551 CG17029 http://flybase.net/reports/FBgn0036551.html protein_coding_gene 0008934=inositol monophosphate 1-phosphatase activity "0016311=dephosphorylation, 0046854=phosphatidylinositol phosphorylation, 0046855=inositol phosphate dephosphorylation" 0005737=cytoplasm IMP "IPR020552=Inositol monophosphatase, Lithium-sensitive, IPR020583=Inositol monophosphatase, metal-binding site, IPR020550=Inositol monophosphatase, conserved site, IPR000760=Inositol monophosphatase" CG17029 16-Dec-15 2015_12 "YDR287W(INM2),YHR046C(INM1)" viable FBgn0085650 CG41489 http://flybase.net/reports/FBgn0085650.html FBan0041489 protein_coding_gene 16-Dec-15 2015_12 FBgn0034138 RpS15 Ribosomal protein S15 http://flybase.net/reports/FBgn0034138.html "FBgn0025547, FBgn0026277" protein_coding_gene "0003723=RNA binding, 0003735=structural constituent of ribosome" "0000022=mitotic spindle elongation, 0006412=translation, 0007052=mitotic spindle organization" "0005737=cytoplasm, 0000228=nuclear chromosome, 0022627=cytosolic small ribosomal subunit, 0005730=nucleolus" "anon-EST:Posey137, CG8332, s15, anon-EST:Posey185, S15" "IPR002222=Ribosomal protein S19/S15, IPR005713=Ribosomal protein S19A/S15e, IPR020934=Ribosomal protein S19 conserved site, IPR023575=Ribosomal protein S19, superfamily" CG8332 16-Dec-15 2015_12 ENSDARG00000070849(rps15) YOL040C(RPS15) WBGene00004484(rps-15) ENSXETG00000003706(rps15) ENSMUSG00000063457(Rps15) ENSG00000115268(RPS15) lethal DRSC07151 EK -0.624074692 -0.792128335 -2.281032805 -3.803663871 1.896970021 3.03628177 FBgn0033138 Tsp42Eq Tetraspanin 42Eq http://flybase.net/reports/FBgn0033138.html protein_coding_gene 0016021=integral component of membrane "CG12832, Dm.Tsp42Eq, tetraspanin 42E" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG12832 16-Dec-15 2015_12 "viable,fertile" FBgn0260030 22F2 http://flybase.net/reports/FBgn0260030.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0259663 B0969 http://flybase.net/reports/FBgn0259663.html gene 16-Dec-15 2015_12 visible wing FBgn0060961 l(3)S032401b lethal (3) S032401b http://flybase.net/reports/FBgn0060961.html gene 0324/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0001534 l(1)14Ab lethal (1) 14Ab http://flybase.net/reports/FBgn0001534.html gene h5c 16-Dec-15 2015_12 lethal FBgn0015477 Rme-8 Receptor mediated endocytosis 8 http://flybase.net/reports/FBgn0015477.html FBgn0033390 protein_coding_gene "0006897=endocytosis, 0007298=border follicle cell migration, 0006898=receptor-mediated endocytosis" "0005875=microtubule associated complex, 0031201=SNARE complex" "rme-8, E(shi)2-1, l(2)45Ba, CG8014" "IPR016024=Armadillo-type fold, IPR025640=Domain of unknown function DUF4339, IPR001623=DnaJ domain, IPR011989=Armadillo-like helical" CG8014 16-Dec-15 2015_12 WBGene00004378(rme-8) ENSG00000138246(DNAJC13) "lethal - all die before end of larval stage,recessive,some die during larval stage,cell size defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "border follicle cell,somatic clone,garland cell & endosome,eye photoreceptor cell,rhabdomere,ommatidium,endosome & garland cell | somatic clone,trichogen cell" FBgn0030051 spirit Serine Protease Immune Response Integrator http://flybase.net/reports/FBgn0030051.html protein_coding_gene 0004252=serine-type endopeptidase activity "0050832=defense response to fungus, 0045752=positive regulation of Toll signaling pathway, 0006508=proteolysis, 0045087=innate immune response, 0050830=defense response to Gram-positive bacterium, 0050829=defense response to Gram-negative bacterium" 0005576=extracellular region "spirit, Serine protease immune response integrator, SP33, Spirit, c-SP33, CG2056" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR001254=Serine proteases, trypsin domain" CG2056 16-Dec-15 2015_12 "immune response defective,viable" FBgn0040822 CG14150 http://flybase.net/reports/FBgn0040822.html protein_coding_gene 16-Dec-15 2015_12 FBgn0051044 CR31044 http://flybase.net/reports/FBgn0051044.html FBgn0062417 non_protein_coding_gene "pri-mir-279_mir-996, BcDNA:SD09455, CG31044" CR31044 16-Dec-15 2015_12 "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "mushroom body & axon7B,Kenyon cell,adult mushroom body,embryonic/larval hemocyte | third instar larval stage" FBgn0003551 su(Cbx) suppressor of Contrabithorax http://flybase.net/reports/FBgn0003551.html FBgn0003552 gene 16-Dec-15 2015_12 FBgn0019640 Antp::ftz Antp::ftz http://flybase.net/reports/FBgn0019640.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0266783 CR45248 http://flybase.net/reports/FBgn0266783.html non_protein_coding_gene CR45248 16-Dec-15 2015_12 FBgn0026644 l(2)k06131 lethal (2) k06131 http://flybase.net/reports/FBgn0026644.html gene 16-Dec-15 2015_12 FBgn0033741 CG8545 http://flybase.net/reports/FBgn0033741.html protein_coding_gene "0008757=S-adenosylmethionine-dependent methyltransferase activity, 0003723=RNA binding" 0006364=rRNA processing 0005730=nucleolus Nol1Nt "IPR023273=RNA (C5-cytosine) methyltransferase, NOP2, IPR011023=Nop2p, IPR023267=RNA (C5-cytosine) methyltransferase, IPR001678=SAM-dependent methyltransferase RsmB/NOP2-type, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR018314=Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site" CG8545 16-Dec-15 2015_12 ENSDARG00000043304(si:dkey-91i17.1) YNL061W(NOP2) WBGene00021073(nol-1) ENSXETG00000011515(NOP2) ENSMUSG00000038279(Nop2) ENSG00000111641(NOP2) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014212 l(2)31Ab lethal (2) 31Ab http://flybase.net/reports/FBgn0014212.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026136 CkIIë_2 Casein kinase II ë_2 subunit http://flybase.net/reports/FBgn0026136.html protein_coding_gene 0019887=protein kinase regulator activity 0006468=protein phosphorylation 0005956=protein kinase CK2 complex "CKIIb2, CG8914, CKIIbeta', CkIIbeta2, dCK2beta', DmCKIIbeta', CK2beta', DmCK2beta', CKIIbeta2, CK2" "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet" CG8914 16-Dec-15 2015_12 YOR039W(CKB2) "lethal,viable" FBgn0000532 E111 E111 http://flybase.net/reports/FBgn0000532.html gene 0005634=nucleus 16-Dec-15 2015_12 FBgn0040071 tara taranis http://flybase.net/reports/FBgn0040071.html "FBgn0010823, FBgn0011312, FBgn0038408, FBgn0063795" protein_coding_gene "0046331=lateral inhibition, 0048190=wing disc dorsal/ventral pattern formation, 0048096=chromatin-mediated maintenance of transcription, 0030431=sleep, 0045475=locomotor rhythm" "CG6889, l(3)jlC5, 5472, anon-WO0257455.25, l(3)j1C5, Tara, l(3)03881, EP(3)3463" IPR009263=SERTA domain CG6889 16-Dec-15 2015_12 "ENSG00000179833(SERTAD2),ENSG00000170779(CDCA4)" "learning defective,viable,lethal,fertile,partially lethal - majority live,visible,recessive,dominant,wild-type,poor,body color defective" "wing,posterior compartment,macrochaeta,wing vein L5,adult abdominal sensillum,ectopic,scutellar bristle,trichogen cell,tormogen cell,arista,haltere,wing vein,eye,chaeta,supernumerary,mesothoracic tergum" FBgn0065911 l(2)SH0180 lethal (2) SH0180 http://flybase.net/reports/FBgn0065911.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022087 l(2)k07406 lethal (2) k07406 http://flybase.net/reports/FBgn0022087.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal" FBgn0005233 l(3)R33 lethal of Roberts 33 http://flybase.net/reports/FBgn0005233.html gene l(3)B33 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0069400 KH5 KH5 http://flybase.net/reports/FBgn0069400.html gene 0016063=rhodopsin biosynthetic process 16-Dec-15 2015_12 FBgn0012000 tRNA:V3b:84Dc transfer RNA:val3b:84Dc http://flybase.net/reports/FBgn0012000.html "FBgn0003853, FBgn0011997, FBgn0051500, FBgn0060025" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033452=GUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:val3b:84Dc, valine tRNA, tRNA[Val][[3b]], Val-3b, tRNA:V3b, tRNA:V:CAC:AE002699-b, CR31500, chr3R.trna75-ValCAC, AE002699.trna2-ValCAC" CR31500 16-Dec-15 2015_12 FBgn0264751 Vti1b Vesicle transport through interaction with t-SNAREs 1b http://flybase.net/reports/FBgn0264751.html "FBgn0051232, FBgn0038614" protein_coding_gene 0005484=SNAP receptor activity 0016192=vesicle-mediated transport "0031201=SNARE complex, 0005794=Golgi apparatus" "CG44009, CG7682, EP(3)1037, Vti1b, CG31232" CG44009 16-Dec-15 2015_12 "viable,fertile" FBgn0030185 CG15310 http://flybase.net/reports/FBgn0030185.html protein_coding_gene 16-Dec-15 2015_12 FBgn0020799 ni-s nicked-similis http://flybase.net/reports/FBgn0020799.html gene 16-Dec-15 2015_12 FBgn0000592 Est-6 Esterase 6 http://flybase.net/reports/FBgn0000592.html FBgn0017620 protein_coding_gene 0052689=carboxylic ester hydrolase activity "0046693=sperm storage, 0007618=mating, 0030728=ovulation, 0046662=regulation of oviposition, 0042811=pheromone biosynthetic process, 0019953=sexual reproduction, 0046008=regulation of female receptivity, post-mating, 0046692=sperm competition, 0032504=multicellular organism reproduction, 0007619=courtship behavior" 0005615=extracellular space "Est-5B, EST-5, Est-D, esterase-6, Est 6, Est, est6, Est6, CG6917, Stress-inducible humoral factor Turandot A, Est-5, est-6, esterase 6, Carboxyl ester hydrolase, EST-6, Esterase-6, EST6, Esterase6" "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site" CG6917 16-Dec-15 2015_12 "WBGene00015077(B0238.13),WBGene00016863(C52A10.2),WBGene00015067(B0238.1)" " adult stage | male , embryonic stage -- adult stage , pupal stage--adult stage " "electrophoretic variant,fast,slow,partially lethal - majority die,some die during pupal stage" FBgn0000545 Extra-combs Extra combs http://flybase.net/reports/FBgn0000545.html gene Eco 16-Dec-15 2015_12 FBgn0002241 l(3)68Cc lethal (3) 68Cc http://flybase.net/reports/FBgn0002241.html gene l(3)C70 16-Dec-15 2015_12 "visible,recessive,lethal" "wing,macrochaeta" FBgn0042098 CG18735 http://flybase.net/reports/FBgn0042098.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP22 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG18735 16-Dec-15 2015_12 "ENSDARG00000056324(zgc:123295),ENSDARG00000046140(zgc:112038),ENSDARG00000055644(zgc:101788),ENSDARG00000070713(zgc:162180),ENSDARG00000070710(wu:fk80d04),ENSDARG00000061858(zgc:153968),ENSDARG00000056773(zgc:163079),ENSDARG00000052064(LOC571079),ENSDARG00000063444,ENSDARG00000070518,ENSDARG00000019714" WBGene00006619(try-1) "ENSXETG00000006302(BC067937.1),ENSXETG00000006299(),ENSXETG00000025963(prss27),ENSXETG00000008526()" "ENSMUSG00000054537(Tmprss11e),ENSMUSG00000048764(Tmprss11f)" viable FBgn0263381 CR43433 http://flybase.net/reports/FBgn0263381.html non_protein_coding_gene CR43433 16-Dec-15 2015_12 FBgn0030722 CG12395 http://flybase.net/reports/FBgn0030722.html protein_coding_gene IPR010441=CH-like domain in sperm protein CG12395 16-Dec-15 2015_12 ENSDARG00000022007(zgc:66426) "ENSMUSG00000027329(Spef1),ENSMUSG00000073795(6430531B16Rik)" ENSG00000101222(SPEF1) viable FBgn0043856 roo\ORF ORF http://flybase.net/reports/FBgn0043856.html FBgn0043855 transposable_element_gene "0004190=aspartic-type endopeptidase activity, 0003676=nucleic acid binding, 0008270=zinc ion binding" "0006508=proteolysis, 0015074=DNA integration" "gag, roo, env, pol, ORF, roo\env" "IPR022048=Protein of unknown function DUF3609, IPR012337=Ribonuclease H-like domain, IPR001995=Peptidase A2A, retrovirus, catalytic, IPR001584=Integrase, catalytic core, IPR005312=Protein of unknown function DUF1759, IPR001878=Zinc finger, CCHC-type, IPR008042=Retrotransposon, Pao, IPR008737=Peptidase aspartic, putative, IPR022058=Protein of unknown function DUF3610" 16-Dec-15 2015_12 FBgn0030247 CG15208 http://flybase.net/reports/FBgn0030247.html FBgn0044564 protein_coding_gene 0046692=sperm competition "lincRNA.977, anon-WO0140519.64" "IPR001611=Leucine-rich repeat, IPR003603=U2A'/phosphoprotein 32 family A, C-terminal" CG15208 16-Dec-15 2015_12 viable FBgn0039093 CG10183 http://flybase.net/reports/FBgn0039093.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG10183 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" viable DRSC14203 K 0.843733208 0.148688822 -0.24731013 0.352897598 -1.785955169 -1.335952468 FBgn0035243 CG13926 http://flybase.net/reports/FBgn0035243.html protein_coding_gene "IPR008493=Domain of unknown function DUF775, IPR031318=OPI10 family" CG13926 16-Dec-15 2015_12 ENSDARG00000040546(zgc:110091) WBGene00018328(F42A6.6) ENSXETG00000010439(C11orf73) ENSMUSG00000062797(l7Rn6) ENSG00000149196(C11orf73) "viable,fertile" FBgn0041745 l(1)em4 lethal (1) em4 http://flybase.net/reports/FBgn0041745.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086055 snoRNA:Me18S-C1096 http://flybase.net/reports/FBgn0086055.html snoRNA_gene "Me18S-Cm1096, Me18S-C1096, CR34684" CR34684 16-Dec-15 2015_12 FBgn0014160 eve::prd eve::prd http://flybase.net/reports/FBgn0014160.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0028838 CSN1a COP9 signalosome subunit 1a http://flybase.net/reports/FBgn0028838.html FBgn0028869 protein_coding_gene "0051726=regulation of cell cycle, 0010388=cullin deneddylation, 0008277=regulation of G-protein coupled receptor protein signaling pathway" 0008180=COP9 signalosome "CG4697, CSN1, Drosophila COP9 signalosome homolog 1, CH1-1, Dch1, COP9, BG:DS06874.2, csn1, Csn1a, COP9 complex homolog subunit 1 a, Dch1-1, Csn1A" "IPR019585=26S proteasome, regulatory subunit Rpn7" CG4697 16-Dec-15 2015_12 WBGene00000813(csn-1) viable FBgn0033317 CG8635 http://flybase.net/reports/FBgn0033317.html protein_coding_gene 0046872=metal ion binding "IPR000571=Zinc finger, CCCH-type" CG8635 16-Dec-15 2015_12 ENSDARG00000015889(zc3h15) YOR091W(TMA46) WBGene00009189(F27D4.4) ENSXETG00000013336(lerepo4) ENSMUSG00000027091(Zc3h15) ENSG00000065548(ZC3H15) "viable,fertile" FBgn0032376 Tsp33B Tetraspanin 33B http://flybase.net/reports/FBgn0032376.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp33B, CG14936" "IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG14936 16-Dec-15 2015_12 "ENSMUSG00000071648(Rom1),ENSMUSG00000023978(Prph2)" "ENSG00000149489(ROM1),ENSG00000112619(PRPH2)" "viable,fertile" DRSC02418 E -0.324509361 0.080316874 -1.630618941 -0.136923901 0.200748664 0.561493451 FBgn0266797 CR45259 http://flybase.net/reports/FBgn0266797.html non_protein_coding_gene CR45259 16-Dec-15 2015_12 FBgn0020792 palla palla http://flybase.net/reports/FBgn0020792.html gene 0048477=oogenesis pla 16-Dec-15 2015_12 "female sterile,recessive" "follicle cell,egg,dorsal appendage" FBgn0003149 Prm Paramyosin http://flybase.net/reports/FBgn0003149.html "FBgn0010949, FBgn0028212" protein_coding_gene "0003774=motor activity, 0008307=structural constituent of muscle" "0030239=myofibril assembly, 0007498=mesoderm development" "0005863=striated muscle myosin thick filament, 0016459=myosin complex" "unnamed, PM/mPM, l(3)S010605, Paramyosin/Miniparamyosin, pm, l(3)10631, mPM, miniparamyosin, paramyosin/miniparamyosin, paramyosin, CG5939, PM, lethal (3) S010605, FBgn0003149, 0106/05, Para, prm" IPR002928=Myosin tail CG5939 16-Dec-15 2015_12 ENSDARG00000071253 WBGene00006754(unc-15) "ENSXETG00000016283(),ENSXETG00000025242(),ENSXETG00000023939(),ENSXETG00000025247(),ENSXETG00000016314(MYH15)" "partially lethal - majority die,recessive,lethal,neurophysiology defective,flight defective,visible,some die during pupal stage" "myofibril,striated muscle myosin thick filament,sarcomere,somatic muscle,trichogen cell" FBgn0011812 Lcp1ë¬ Larval cuticle protein 1 pseudogene http://flybase.net/reports/FBgn0011812.html FBgn0050367 pseudogene_attribute "CG30367, PsiLcp, CR30367, LcpPsi, PsiI, Lcp1Psi, Psigene I, Psi1" CR30367 16-Dec-15 2015_12 FBgn0083114 W41 W41 http://flybase.net/reports/FBgn0083114.html gene 16-Dec-15 2015_12 viable wing FBgn0266250 CR44945 http://flybase.net/reports/FBgn0266250.html non_protein_coding_gene lincRNA.798 CR44945 16-Dec-15 2015_12 FBgn0266051 CR44816 http://flybase.net/reports/FBgn0266051.html non_protein_coding_gene CR44816 16-Dec-15 2015_12 FBgn0082588 ms(2)n55 male sterile (2) n55 http://flybase.net/reports/FBgn0082588.html gene "0035039=male pronucleus assembly, 0035037=sperm entry" n55 16-Dec-15 2015_12 FBgn0060701 l(3)S071705 lethal (3) S071705 http://flybase.net/reports/FBgn0060701.html gene 0717/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0028643 bls bractless http://flybase.net/reports/FBgn0028643.html gene 16-Dec-15 2015_12 FBgn0259734 Nost Nostrin http://flybase.net/reports/FBgn0259734.html "FBgn0053224, FBgn0030076, FBgn0030075, FBgn0260485, FBgn0260449, FBgn0260448" protein_coding_gene "0008289=lipid binding, 0005543=phospholipid binding" "0030708=germarium-derived female germ-line cyst encapsulation, 1903391=regulation of adherens junction organization, 0097320=membrane tubulation, 0007009=plasma membrane organization, 0035317=imaginal disc-derived wing hair organization" 0005768=endosome "nost, NOSTRIN, CG15364, nostrin, CG33224, CG4040, CG42388" "IPR001452=SH3 domain, IPR001060=FCH domain, IPR031160=F-BAR domain" CG42388 16-Dec-15 2015_12 "ENSDARG00000060860(pstpip1a),ENSDARG00000053568(pstpip1b)" WBGene00007983(C36E8.4) ENSXETG00000016209(NOSTRIN) ENSMUSG00000034738(Nostrin) ENSG00000163072(NOSTRIN) FBgn0083042 snoRNA:ë¬18S-1854a snoRNA:ë¬18S-1854a http://flybase.net/reports/FBgn0083042.html snoRNA_gene "Psi18S-1854a, psi18S-1854a, Psi 18S-1854a, CR34602, chrX:16979867..16979988" CR34602 16-Dec-15 2015_12 FBgn0002600 M(2)40c Minute (2) 40c http://flybase.net/reports/FBgn0002600.html gene 16-Dec-15 2015_12 "Minute,dominant,visible" macrochaeta FBgn0002892 mus206 mutagen-sensitive 206 http://flybase.net/reports/FBgn0002892.html gene 0006302=double-strand break repair 16-Dec-15 2015_12 "chemical sensitive,recessive,radiation sensitive,DNA repair defective,sterile" FBgn0060292 snoRNA:U49:66Da snoRNA:U49:66Da http://flybase.net/reports/FBgn0060292.html snoRNA_gene "Dmel\U49a, CR32911, Me28S-C3341(U49), U49a" CR32911 16-Dec-15 2015_12 FBgn0028704 Nckx30C Nckx30C http://flybase.net/reports/FBgn0028704.html "FBgn0032141, FBgn0042190" protein_coding_gene "0008273=calcium, potassium:sodium antiporter activity" "0048812=neuron projection morphogenesis, 0048749=compound eye development, 0006816=calcium ion transport, 0055085=transmembrane transport, 0006814=sodium ion transport" 0016021=integral component of membrane "CG18660, NcKX30C, potassium-dependent sodium/calcium, CG4106, NckX30C" "IPR004481=Sodium/potassium/calcium exchanger, IPR030243=Sodium/potassium/calcium exchanger NCKX30C-like, IPR004837=Sodium/calcium exchanger membrane region" CG18660 16-Dec-15 2015_12 "ENSDARG00000015425(zgc:112072),ENSDARG00000006760(slc24a3),ENSDARG00000067509,ENSDARG00000041086" YDL206W() "WBGene00003569(ncx-4),WBGene00003570(ncx-5)" ENSXETG00000023099(SLC24A2) ENSMUSG00000037996(Slc24a2) ENSG00000155886(SLC24A2) " embryonic stage | stage 13 , adult stage , larval stage | third instar , embryonic stage | stage 15-16 , embryonic stage | stage 16 , embryonic stage -- adult stage " " embryonic central nervous system

, eye

, dorsal mesothoracic disc | restricted

, ventral thoracic disc | restricted

, ventral nerve cord

, eye-antennal disc | restricted

, brain | restricted

, embryonic brain

, head

, dorsal metathoracic disc | restricted

" "viable,fertile" FBgn0263088 CR43356 http://flybase.net/reports/FBgn0263088.html non_protein_coding_gene CR43356 16-Dec-15 2015_12 FBgn0267143 CR45583 http://flybase.net/reports/FBgn0267143.html non_protein_coding_gene CR45583 16-Dec-15 2015_12 FBgn0011290 Taf12 TBP-associated factor 12 http://flybase.net/reports/FBgn0011290.html "FBgn0011303, FBgn0011304" protein_coding_gene "0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0001129=TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly, 0004402=histone acetyltransferase activity" "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0007221=positive regulation of transcription of Notch receptor target, 0043966=histone H3 acetylation, 0006367=transcription initiation from RNA polymerase II promoter" "0005669=transcription factor TFIID complex, 0005634=nucleus, 0000124=SAGA complex" "dTAFII30, 26kDa polypeptide, dTAF22, dTAF12, TAF[II]30alpha, Taf[[II]]30alpha, dTAFII30 alpha, TAF[[II]]230, TFIID 28, TAF[[II]]30alpha/28 TAF[[II]]22, TAF[[II]]30alpha/28/22, CG17358, dmTAF12, TAF30a, d28/22, TAFII30alpha/22, TAF30alpha/28/22, TFIID, TAF[[II]]30alpha, TAF, dTAF[[II]]30, Taf22, Taf32, Taf28, TAF30alpha, dTAF28, TFIID 22, TAF30alpha/28, TAF12, TBP-associated factor, p22, Taf30alpha, p28, TFIID-p28, dTAF[[II]]30alpha, TBP-associated factor 30kD subunit alpha, dTAF[[II]]30alpha/22, T2DA_DROME, TAF[[II]]" "IPR003228=Transcription initiation factor TFIID, IPR009072=Histone-fold" CG17358 16-Dec-15 2015_12 "ENSDARG00000054085(taf12),ENSDARG00000053969" WBGene00006396(taf-12) ENSXETG00000020616(TAF12) ENSMUSG00000028899(Taf12) ENSG00000120656(TAF12) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC28181 IK 0.158766024 2.314028454 -0.665535627 0.894596532 1.000345435 4.628406568 FBgn0260651 l(3)76BDh lethal (3) 76BDh http://flybase.net/reports/FBgn0260651.html gene 16-Dec-15 2015_12 FBgn0030911 CR15061 http://flybase.net/reports/FBgn0030911.html non_protein_coding_gene CG15061 CR15061 16-Dec-15 2015_12 DRSC28470 K -0.433916443 0.287138948 -0.168484679 0.041678996 -1.674889766 0.002883187 FBgn0037488 CG14607 http://flybase.net/reports/FBgn0037488.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14607 16-Dec-15 2015_12 viable DRSC12551 I 1.584014649 0.861477607 -0.028439761 0.503654287 0.00483301 1.021456109 FBgn0010611 Hmgs HMG Coenzyme A synthase http://flybase.net/reports/FBgn0010611.html "FBgn0034115, FBgn0034116" protein_coding_gene 0004421=hydroxymethylglutaryl-CoA synthase activity "0022008=neurogenesis, 0008299=isoprenoid biosynthetic process, 0001700=embryonic development via the syncytial blastoderm, 0046331=lateral inhibition" "hydroxy-3-methylglutaryl-CoA synthase, HMG-CoA synthase, l(2)06214, Ov25, CG4311, HMGS, CG16796" "IPR013746=Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain, IPR010122=Hydroxymethylglutaryl-CoA synthase, eukaryotic, IPR013528=Hydroxymethylglutaryl-coenzyme A synthase, N-terminal, IPR016039=Thiolase-like, IPR000590=Hydroxymethylglutaryl-coenzyme A synthase, active site" CG4311 16-Dec-15 2015_12 ENSDARG00000052738(LOC100334232) YML126C(ERG13) WBGene00017769(F25B4.6) ENSXETG00000016587(HMGCS1) "ENSMUSG00000079828,ENSMUSG00000079301,ENSMUSG00000027875(Hmgcs2)" "ENSG00000112972(HMGCS1),ENSG00000134240(HMGCS2)" "viable,fertile,lethal,recessive,maternal effect,poor,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/first instar larval cuticle,maternal effect,abdomen,dorsal,posterior,embryonic/larval neuroblast,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0028004 l(3)S119005 lethal (3) S119005 http://flybase.net/reports/FBgn0028004.html gene 1190/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0020812 mei(1)g13 mei(1)g13 http://flybase.net/reports/FBgn0020812.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,female" FBgn0040957 CG14272 http://flybase.net/reports/FBgn0040957.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267564 CR45904 http://flybase.net/reports/FBgn0267564.html non_protein_coding_gene CR45904 16-Dec-15 2015_12 FBgn0053499 Sdic4 Sperm-specific dynein intermediate chain 4 http://flybase.net/reports/FBgn0053499.html protein_coding_gene 0003777=microtubule motor activity 0007018=microtubule-based movement "0005858=axonemal dynein complex, 0036126=sperm flagellum" "Sdic:CG33499, CG33499, unnamed" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR025956=Cytoplasmic dynein 1 intermediate chain 1/2" CG33499 16-Dec-15 2015_12 "ENSDARG00000005756(dync1i2a),ENSDARG00000022487,ENSDARG00000060948(zgc:158394),ENSDARG00000063383(dync1i2b)" YDR488C(PAC11) WBGene00015927(dyci-1) "ENSXETG00000020285(dnci2),ENSXETG00000020277(DYNC1I1)" "ENSMUSG00000027012(Dync1i2),ENSMUSG00000029757(Dync1i1)" "ENSG00000077380(DYNC1I2),ENSG00000158560(DYNC1I1)" FBgn0011862 tRNA:G3:35Ba transfer RNA:gly3:35Ba http://flybase.net/reports/FBgn0011862.html "FBgn0003778, FBgn0051977, FBgn0060223" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033462=GGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2L.trna19-GlyGCC, BG:DS04641.3, tRNA:G:GCC:AE002690-b, tRNA[Gly-GCC], tRNA:gly3:35Ba, CR31977, AE002690.trna10-GlyGCC" CR31977 16-Dec-15 2015_12 FBgn0266825 CR45287 http://flybase.net/reports/FBgn0266825.html non_protein_coding_gene CR45287 16-Dec-15 2015_12 FBgn0038246 CG14853 http://flybase.net/reports/FBgn0038246.html protein_coding_gene "IPR026703=Glutamate-rich protein 2, IPR011990=Tetratricopeptide-like helical domain" CG14853 16-Dec-15 2015_12 viable FBgn0263046 CG43341 http://flybase.net/reports/FBgn0263046.html "FBgn0033197, FBgn0033198, FBgn0040781, FBgn0063175, FBan0030492, FBgn0050492" protein_coding_gene CG30492 CG43341 16-Dec-15 2015_12 FBgn0001785 l(1)M83 lethal (1) M83 http://flybase.net/reports/FBgn0001785.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0016710 Reg-15 Rhythmically expressed gene 15 http://flybase.net/reports/FBgn0016710.html gene "Dreg-15, Drosophila Rhythmically expressed gene 15" 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0265044 CR44161 http://flybase.net/reports/FBgn0265044.html non_protein_coding_gene CR44161 16-Dec-15 2015_12 FBgn0001147 gsb-n gooseberry-neuro http://flybase.net/reports/FBgn0001147.html protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007367=segment polarity determination, 0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis" "0005667=transcription factor complex, 0005634=nucleus" "gooseberry, Gsb-p, BSH4, gooseberry-neuro, gsb proximal, BSH-4, gsbN, gooseberry proximal, gsb-proximal, GsbN, CG2692, gsb-neuro, Gsbn, gsb-p, gsbn, gsbp, gsb, gooseberry neuro" "IPR001356=Homeobox domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001523=Paired domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG2692 16-Dec-15 2015_12 "ENSDARG00000070818,ENSDARG00000020821" "ENSXETG00000018527(PAX7),ENSXETG00000007640(pax3)" " embryonic stage | stage 12 , embryonic stage | stage 13 , embryonic stage | late , embryonic stage | >=stage 9 , embryonic stage | stage 11 , larval stage , embryonic stage | 4-12 hr , embryonic stage | stage 9 , embryonic stage " " embryonic neuroblast

, embryonic neuron | segmentally repeated pattern

, organism | striped

, ventral neurogenic region | segmentally repeated

, epidermis

, neuroblast

, ventral nervous system

" " embryonic stage | stage >13 , embryonic stage | stage >11 , embryonic stage | stage 10 , embryonic stage | stage >10 , larval stage | third instar " " neuron &&of abdominal segment 9

, embryonic neuron | segmentally repeated pattern

, ganglion mother cell

, anal pad

, embryonic/larval pharynx

, embryonic neuron

, ventral oblique muscle

, female genital disc | restricted

, neuron &&of embryonic brain

, male genital disc | restricted

, neuroblast

" "partially lethal - majority live,partially lethal - majority die,recessive,pair rule phenotype,wild-type" "RP2 motor neuron,EL neuron,U neuron,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic epidermis,Keilin's organ,aCC neuron,pCC neuron" FBgn0011101 l(1)Q62 lethal (1) Q62 http://flybase.net/reports/FBgn0011101.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0037878 CG6693 http://flybase.net/reports/FBgn0037878.html protein_coding_gene "IPR018253=DnaJ domain, conserved site, IPR001623=DnaJ domain" CG6693 16-Dec-15 2015_12 "ENSDARG00000071734,ENSDARG00000031293(zgc:92648)" WBGene00001041(dnj-23) ENSXETG00000007481(dnajc9) ENSMUSG00000021811(Dnajc9) ENSG00000213551(DNAJC9) FBgn0025104 CalpII Calpain II http://flybase.net/reports/FBgn0025104.html gene 0004198=calcium-dependent cysteine-type endopeptidase activity 0006508=proteolysis 16-Dec-15 2015_12 FBgn0050334 CG30334 http://flybase.net/reports/FBgn0050334.html FBgn0045361 protein_coding_gene NEST:bs09a11 CG30334 16-Dec-15 2015_12 viable FBgn0010847 l(3)04708 lethal (3) 04708 http://flybase.net/reports/FBgn0010847.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0259580 B2026 http://flybase.net/reports/FBgn0259580.html gene 16-Dec-15 2015_12 visible wing FBgn0267423 CR45776 http://flybase.net/reports/FBgn0267423.html pseudogene_attribute CR45776 16-Dec-15 2015_12 FBgn0036439 CG13474 http://flybase.net/reports/FBgn0036439.html FBgn0063699 protein_coding_gene 0004001=adenosine kinase activity 0006166=purine ribonucleoside salvage BcDNA:AT29351 "IPR011611=Carbohydrate kinase PfkB, IPR029056=Ribokinase-like, IPR001805=Adenosine kinase" CG13474 16-Dec-15 2015_12 viable DRSC10018 IE 0.010564706 -1.832633119 0.054269873 -1.839346939 -0.987484971 0.423756823 FBgn0011191 l(1)296-19 lethal (1) 296-19 http://flybase.net/reports/FBgn0011191.html FBgn0010201 gene 296-19 16-Dec-15 2015_12 "lethal,recessive" FBgn0035478 CG10853 http://flybase.net/reports/FBgn0035478.html FBgn0061412 protein_coding_gene 0003677=DNA binding "0006355=regulation of transcription, DNA-templated" BcDNA:LP09837 "IPR003851=Zinc finger, Dof-type" CG10853 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC23600 IK -0.322274411 1.896518952 0.242037808 0.629290473 -1.511820929 0.244926703 FBgn0024853 moz mozzarella http://flybase.net/reports/FBgn0024853.html gene 0007283=spermatogenesis "moz1, ms(2)5720, ms(2)UK, moz2" 16-Dec-15 2015_12 "male sterile,recessive,viable" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus" FBgn0000548 E(da) Enhancer of daughterless http://flybase.net/reports/FBgn0000548.html gene 16-Dec-15 2015_12 FBgn0031155 CG15446 http://flybase.net/reports/FBgn0031155.html protein_coding_gene 0046872=metal ion binding "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG15446 16-Dec-15 2015_12 viable FBgn0038274 Nup93-2 Nucleoporin 93kD-2 http://flybase.net/reports/FBgn0038274.html protein_coding_gene 0017056=structural constituent of nuclear pore "0006999=nuclear pore organization, 0006810=transport" "0044615=nuclear pore nuclear basket, 0005643=nuclear pore" "nup93, Nucleoporin 93, Nup93, CG7262, Cg7262" IPR007231=Nucleoporin interacting component Nup93/Nic96 CG7262 16-Dec-15 2015_12 ENSDARG00000003487(dye) YFR002W(NIC96) WBGene00003799(npp-13) ENSXETG00000018461(NUP93) ENSMUSG00000032939(Nup93) ENSG00000102900(NUP93) viable FBgn0030617 CG9095 http://flybase.net/reports/FBgn0030617.html protein_coding_gene 0030246=carbohydrate binding CT26106 "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR000436=Sushi/SCR/CCP domain, IPR001304=C-type lectin, IPR018378=C-type lectin, conserved site, IPR008979=Galactose-binding domain-like" CG9095 16-Dec-15 2015_12 WBGene00008314(C54G4.4) "viable,fertile" FBgn0260221 5-SZ-3716 http://flybase.net/reports/FBgn0260221.html gene 16-Dec-15 2015_12 visible "sex comb,sex comb tooth" FBgn0034401 MetRS Methionyl-tRNA synthetase http://flybase.net/reports/FBgn0034401.html FBgn0025966 protein_coding_gene "0005524=ATP binding, 0004825=methionine-tRNA ligase activity" "0022008=neurogenesis, 0006431=methionyl-tRNA aminoacylation" "0005875=microtubule associated complex, 0005737=cytoplasm, 0017101=aminoacyl-tRNA synthetase multienzyme complex" "anon-EST:Liang-2.15, methionyl-tRNA synthetase, dMetRS, clone 2.15, CG15100, p120, MRS, MetRS" "IPR014758=Methionyl-tRNA synthetase, IPR029038=Methionyl-tRNA synthetase, Zn-domain, IPR004046=Glutathione S-transferase, C-terminal, IPR009068=S15/NS1, RNA-binding, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR000738=WHEP-TRS domain, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR023458=Methionine-tRNA ligase, type 1, IPR015413=Methionyl/Leucyl tRNA synthetase" CG15100 16-Dec-15 2015_12 ENSDARG00000034396(mars) YGR264C(MES1) WBGene00003415(mars-1) ENSXETG00000025174(MARS) ENSMUSG00000040354(Mars) ENSG00000166986(MARS) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0034665 CG4372 http://flybase.net/reports/FBgn0034665.html protein_coding_gene 0003948=N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity "IPR000246=Peptidase T2, asparaginase 2, IPR029055=Nucleophile aminohydrolases, N-terminal" CG4372 16-Dec-15 2015_12 viable FBgn0027130 l(3)C109 lethal (3) C109 http://flybase.net/reports/FBgn0027130.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0262879 CR43234 http://flybase.net/reports/FBgn0262879.html non_protein_coding_gene CG43234 CR43234 16-Dec-15 2015_12 FBgn0027158 l(2)PN-6 lethal (2) PN-6 http://flybase.net/reports/FBgn0027158.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265398 EP1618 http://flybase.net/reports/FBgn0265398.html gene 16-Dec-15 2015_12 FBgn0243511 psidin phagocyte signaling impaired http://flybase.net/reports/FBgn0243511.html "FBgn0043894, FBgn0038764" protein_coding_gene "0006911=phagocytosis, engulfment, 0006955=immune response, 0006959=humoral immune response, 0043524=negative regulation of neuron apoptotic process, 0007298=border follicle cell migration, 0002253=activation of immune response, 0010592=positive regulation of lamellipodium assembly, 0097374=sensory neuron axon guidance" "0005764=lysosome, 0005737=cytoplasm, 0031416=NatB complex" "psid, immune response deficient 16, ird16, CG4845, psidin" "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019183=N-acetyltransferase B complex, non-catalytic subunit" CG4845 16-Dec-15 2015_12 YOL076W(MDM20) WBGene00020068(cra-1) ENSXETG00000004301(NAA25) ENSMUSG00000042719(Naa25) ENSG00000111300(NAA25) FBgn0016840 l(1)MZ9 lethal (1) MZ9 http://flybase.net/reports/FBgn0016840.html gene M9 16-Dec-15 2015_12 "lethal,recessive" FBgn0261878 Z2-2729 http://flybase.net/reports/FBgn0261878.html gene 0030431=sleep 16-Dec-15 2015_12 behavior defective FBgn0051025 Ppi1 Protein phosphatase 1c interacting protein 1 http://flybase.net/reports/FBgn0051025.html "FBgn0039746, FBgn0044531" protein_coding_gene 0008157=protein phosphatase 1 binding "anon-WO0140519.94, CG31025, ppi1, CG2164" CG31025 16-Dec-15 2015_12 viable DRSC15421 E -0.336677409 -0.582472439 -1.762603895 -0.686971283 -0.348750529 1.307820621 FBgn0264280 Su(Mir)3D1-1 http://flybase.net/reports/FBgn0264280.html gene 16-Dec-15 2015_12 lethal FBgn0052069 CG32069 http://flybase.net/reports/FBgn0052069.html FBgn0036119 protein_coding_gene 0022008=neurogenesis 0012505=endomembrane system CG6316 IPR013880=Yos1-like CG32069 16-Dec-15 2015_12 ENSDARG00000039601 YER074W-A(YOS1) WBGene00012371(W09G3.8) ENSXETG00000021523(IER3IP1) ENSG00000134049(IER3IP1) "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0052219 CG32219 http://flybase.net/reports/FBgn0052219.html FBgn0063305 protein_coding_gene BcDNA:AT25132 CG32219 16-Dec-15 2015_12 viable FBgn0054006 CR34006 http://flybase.net/reports/FBgn0054006.html FBgn0082896 non_protein_coding_gene "BP1010, unnamed, CG34006" CR34006 16-Dec-15 2015_12 FBgn0005170 l(2)G571 lethal (2) G571 http://flybase.net/reports/FBgn0005170.html gene 16-Dec-15 2015_12 lethal FBgn0060387 l(3)S134304b lethal (3) S134304b http://flybase.net/reports/FBgn0060387.html gene 1343/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0051889 tRNA:CR31889 transfer RNA:CR31889 http://flybase.net/reports/FBgn0051889.html "FBgn0011843, FBgn0060262" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033458=GAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Asp-GTC], CR31889, tRNA:D:GTC:AE002690-c, tRNA:asp2:29E, AE002690.trna7-AspGTC, tRNA:D2:29E, transfer RNA:asp2:29E, tRNA[[Asp]], chr2L.trna16-AspGTC" CR31889 16-Dec-15 2015_12 FBgn0044387 Scim7 Sensitized chromosome inheritance modifier 7 http://flybase.net/reports/FBgn0044387.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0047205 CR32385 http://flybase.net/reports/FBgn0047205.html "FBgn0052385, FBgn0062157" non_protein_coding_gene "BcDNA:LD18889, anon-WO0118547.23, LD18889" CR32385 16-Dec-15 2015_12 FBgn0060739 l(3)S066620b lethal (3) S066620b http://flybase.net/reports/FBgn0060739.html gene 0666/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0003440 smh smaller thinner http://flybase.net/reports/FBgn0003440.html gene 16-Dec-15 2015_12 "viable,fertile,visible" macrochaeta FBgn0267252 Gë_30A http://flybase.net/reports/FBgn0267252.html "FBgn0028433, FBgn0032107, FBgn0032108, FBgn0263984" protein_coding_gene "0046982=protein heterodimerization activity, 0004871=signal transducer activity" "0071244=cellular response to carbon dioxide, 0007602=phototransduction, 0007186=G-protein coupled receptor signaling pathway" "0016028=rhabdomere, 0005834=heterotrimeric G-protein complex, 0005737=cytoplasm, 0005886=plasma membrane" "CG3694, lincRNA.S701, Galpha30A, Ggamma, Ggammae, Ggamma30A, G[[gamma]], Ggamma[[e]], G-gamma30A, CG43733, CG18511, G[[gamma30A]], G protein gamma30A" "IPR015898=G-protein gamma-like domain, IPR001770=G-protein, gamma subunit" CG3694 16-Dec-15 2015_12 "ENSDARG00000037921(gng13b),ENSDARG00000024740(gng13a)" WBGene00001682(gpc-2) ENSXETG00000005775(gng13) ENSMUSG00000025739(Gng13) ENSG00000127588(GNG13) adult stage head

adult stage " medulla

, photoreceptor cell

, lamina

" FBgn0024326 Mkk4 MAP kinase kinase 4 http://flybase.net/reports/FBgn0024326.html "FBgn0024950, FBgn0040310" protein_coding_gene "0004708=MAP kinase kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0008545=JUN kinase kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0007254=JNK cascade, 0048812=neuron projection morphogenesis, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0048666=neuron development, 0007257=activation of JUN kinase activity" 0030424=axon "142758_at, dMkk4, Map kinase kinase 4, JNK kinase 2, CG9738, MAPK kinase 4, CT27508, mkk4, map kinase kinase 4, Mpk4, hep, DMKK4, SEK1/MKK4, D-MKK4, MAPKK4, MAP kinase kinase 4, MKK4, dMKK4, JNKK2, Drosophila MAP kinase kinase 4" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG9738 16-Dec-15 2015_12 ENSDARG00000063583(map2k4) YJL128C(PBS2) "WBGene00003368(mkk-4),WBGene00012162(VZC374L.1)" ENSXETG00000011036(MAP2K4) ENSMUSG00000033352(Map2k4) ENSG00000065559(MAP2K4) embryonic stage "

ubiquitous , ventral nerve cord

" "neuroanatomy defective,somatic clone,viable,visible" "Kenyon cell,somatic clone,axon | somatic clone,trichogen cell" FBgn0267431 Myo81F Myosin 81F http://flybase.net/reports/FBgn0267431.html "FBgn0261336, FBan0015831, FBgn0040034, FBan0040155, FBgn0058155, FBgn0261337, FBan0041518, FBgn0085663, FBgn0261338, FBan0040204, FBgn0058204, FBgn0261339, FBan0041281, FBgn0085597, FBan0041527, FBgn0085670" protein_coding_gene "0005524=ATP binding, 0042623=ATPase activity, coupled, 0003774=motor activity" 0007165=signal transduction 0016459=myosin complex "CG42623, CG42624, CG42622, CG15831, CG40155, CG45784, CG41518, CG40204, CG42621, CG41281, CG41527" "IPR029071=Ubiquitin-related domain, IPR001609=Myosin head, motor domain, IPR000159=Ras-associating (RA) domain, IPR019748=FERM central domain, IPR000857=MyTH4 domain, IPR000048=IQ motif, EF-hand binding site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000299=FERM domain" CG45784 16-Dec-15 2015_12 FBgn0067668 p160M p160M http://flybase.net/reports/FBgn0067668.html gene p160 16-Dec-15 2015_12 FBgn0040550 CG14389 http://flybase.net/reports/FBgn0040550.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000978 fs(2)HO164 female sterile (2) HO164 http://flybase.net/reports/FBgn0000978.html gene fs(2)164A 16-Dec-15 2015_12 FBgn0260503 Pkc53E::Pkn http://flybase.net/reports/FBgn0260503.html engineered_fusion_gene Pkn-PKC53E 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0037040 CG12983 http://flybase.net/reports/FBgn0037040.html FBgn0045150 protein_coding_gene "bs29a07.y1, NEST:bs29a07" IPR022110=Casc1 domain CG12983 16-Dec-15 2015_12 viable FBgn0283471 wupA wings up A http://flybase.net/reports/FBgn0283471.html "FBgn0025518, FBgn0004028, FBgn0026829" protein_coding_gene "0003779=actin binding, 0005523=tropomyosin binding" "0048738=cardiac muscle tissue development, 0046716=muscle cell cellular homeostasis, 0060047=heart contraction, 0007507=heart development, 0007517=muscle organ development, 0007399=nervous system development, 0000280=nuclear division, 0030239=myofibril assembly, 0007629=flight behavior, 0045214=sarcomere organization, 0007519=skeletal muscle tissue development" "0005861=troponin complex, 0005634=nucleus" "Troponin-I, hdp-a, troponin-I, TnI, Troponin I, fliH, HLI, HL-I, troponin, DROTROPONI, held up, heldup-a, TpnI, held-up, DmTpnI, hdp2, Tn I, CG7178, wings-up A, haplo-lethal region I, held-up2, WupA, wup-A, HL08042, chrX:17947374..17947524, flightless-H, HDP, flightless H, heldup, troponin I, hdp, wings up" IPR001978=Troponin CG7178 16-Dec-15 2015_12 "ENSDARG00000029995(tnni2b.2),ENSDARG00000035958(tnni2b.1),ENSDARG00000029069(tnni2a.4),ENSDARG00000045592(tnni2a.1),ENSDARG00000013752(tnni2a.3),ENSDARG00000005841(tnni2a.2),ENSDARG00000052708(tnni1b),ENSDARG00000070827(zgc:112242),ENSDARG00000042559(zgc:153662),ENSDARG00000016728,ENSDARG00000036671(tnni1al),ENSDARG00000000474(LOC558408),ENSDARG00000028343" "WBGene00006586(tni-4),WBGene00006764(unc-27),WBGene00006585(tni-3)" "ENSXETG00000024676(tnni3),ENSXETG00000004621(tnni2),ENSXETG00000023613(tnni1),ENSXETG00000017087(TNNI1)" "ENSMUSG00000035458(Tnni3),ENSMUSG00000026418(Tnni1),ENSMUSG00000031097(Tnni2)" "ENSG00000130598(TNNI2),ENSG00000159173(TNNI1),ENSG00000129991(TNNI3)" FBgn0070051 37 37 http://flybase.net/reports/FBgn0070051.html gene 0001754=eye photoreceptor cell differentiation #37 16-Dec-15 2015_12 FBgn0052392 CG32392 http://flybase.net/reports/FBgn0052392.html "FBgn0035716, FBgn0040839" protein_coding_gene 0008017=microtubule binding 0007017=microtubule-based process 0005875=microtubule associated complex "CG10099, CG14912" IPR009290=Radial spoke 3 CG32392 16-Dec-15 2015_12 ENSDARG00000043470(rsph3) "ENSMUSG00000073471(Rsph3a),ENSMUSG00000023806(Rsph3b)" ENSG00000130363(RSPH3) viable DRSC10211 K 0.749526917 0.218008449 0.249511587 0.641071253 0.5324798 -1.727269421 FBgn0062614 Mod(var)1260 Mod(var)1260 http://flybase.net/reports/FBgn0062614.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1260 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0026684 l(1)G0078 lethal (1) G0078 http://flybase.net/reports/FBgn0026684.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025178 l(1)1070 lethal (1) 1070 http://flybase.net/reports/FBgn0025178.html gene 16-Dec-15 2015_12 "lethal,recessive" "egg chamber,maternal effect,somatic clone,chorion | maternal effect | somatic clone,follicle cell" FBgn0015458 l(2)37CDc lethal (2) 37CDc http://flybase.net/reports/FBgn0015458.html FBgn0013293 gene l(2)E151 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" macrochaeta FBgn0267200 CR45640 http://flybase.net/reports/FBgn0267200.html non_protein_coding_gene CR45640 16-Dec-15 2015_12 FBgn0020833 l(2)NA "North Amherst, Mass" http://flybase.net/reports/FBgn0020833.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051551 CG31551 http://flybase.net/reports/FBgn0051551.html FBgn0037353 protein_coding_gene CG11005 CG31551 16-Dec-15 2015_12 lethal DRSC22403 I 1.234520337 -1.892002965 1.212805483 0.329119309 0.651052808 0.19906572 FBgn0014976 l(1)64 lethal (1) 64 http://flybase.net/reports/FBgn0014976.html gene 16-Dec-15 2015_12 lethal FBgn0032753 CG17572 http://flybase.net/reports/FBgn0032753.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH64, c-SPH64" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG17572 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0052368 CG32368 http://flybase.net/reports/FBgn0052368.html FBgn0064793 protein_coding_gene BcDNA:RH61042 CG32368 16-Dec-15 2015_12 viable FBgn0050465 CG30465 http://flybase.net/reports/FBgn0050465.html FBgn0064790 protein_coding_gene BcDNA:RH63320 16-Dec-15 2015_12 FBgn0067884 Mod(Prat:bw)1-3 Mod(Prat:bw)1-3 http://flybase.net/reports/FBgn0067884.html gene Mod-1-3 16-Dec-15 2015_12 FBgn0067666 p58 p58 http://flybase.net/reports/FBgn0067666.html gene 16-Dec-15 2015_12 FBgn0036670 CG13029 http://flybase.net/reports/FBgn0036670.html "FBgn0061425, FBgn0062054" protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "anon-WO0118547.38, BcDNA:AT31918" "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG13029 16-Dec-15 2015_12 ENSDARG00000036364(zdhhc24) YOL003C(PFA4) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266492 SclB Sarcolamban B http://flybase.net/reports/FBgn0266492.html "FBgn0047133, FBgn0045775, FBgn0051696" protein_coding_gene 0055117=regulation of cardiac muscle contraction "scl, pncr003, CG45091, mel2, BEST:LP06756, pncr:003:2L, BcDNA:RE28911, pncr003:2L ORFB, ORF-B, CR31696, sarcolamban, pncr003:2L" CG45091 16-Dec-15 2015_12 adult heart FBgn0067355 l(3)95EFa lethal (3) 95EFa http://flybase.net/reports/FBgn0067355.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013941 E(sina)6 Enhancer of seven in absentia 6 http://flybase.net/reports/FBgn0013941.html gene 16-Dec-15 2015_12 photoreceptor cell R7 FBgn0265492 BG01602 http://flybase.net/reports/FBgn0265492.html gene 16-Dec-15 2015_12 FBgn0069182 mcl(2)Z0338 mcl(2)Z0338 http://flybase.net/reports/FBgn0069182.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0038585 Non3 Novel nucleolar protein 3 http://flybase.net/reports/FBgn0038585.html protein_coding_gene "0022008=neurogenesis, 0090307=mitotic spindle assembly" 0005730=nucleolus "CG7993, Non3" IPR007109=Brix domain CG7993 16-Dec-15 2015_12 ENSDARG00000043960(rpf2) YKR081C(RPF2) WBGene00021830(Y54E10A.10) ENSXETG00000021335(bxdc1) ENSMUSG00000038510(Rpf2) ENSG00000197498(RPF2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0250731 5.8SrRNA:CR40454 5.8SrRNA:CR40454 http://flybase.net/reports/FBgn0250731.html "FBgn0058454, FBgn0085735, FBan0040454" rRNA_gene CR40454 CR40454 16-Dec-15 2015_12 FBgn0029962 CG1402 http://flybase.net/reports/FBgn0029962.html protein_coding_gene 0004089=carbonate dehydratase activity "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class" CG1402 16-Dec-15 2015_12 "ENSDARG00000009568(LOC568543),ENSDARG00000052644(ca10a)" "WBGene00000280(cah-2),WBGene00000279(cah-1)" "ENSXETG00000001296(CA10),ENSXETG00000014383(CA11)" "ENSMUSG00000056158(Car10),ENSMUSG00000003273(Car11)" "ENSG00000154975(CA10),ENSG00000063180(CA11)" viable DRSC17905 I -0.312340393 1.769573916 -0.106505895 0.307861083 -0.252666746 -0.153191377 FBgn0028430 He Hemese http://flybase.net/reports/FBgn0028430.html "FBgn0044869, FBgn0051770" protein_coding_gene "0045087=innate immune response, 0035204=negative regulation of lamellocyte differentiation, 0035010=encapsulation of foreign target" "hem, Gustav, unnamed, CG31770, Hemes, H2, hemese, hemes, he" CG31770 16-Dec-15 2015_12 "immune response defective,viable" "lamellocyte,ectopic,hemocyte" FBgn0259866 Su(Ste):CR42435 Su(Ste):CR42435 http://flybase.net/reports/FBgn0259866.html non_protein_coding_gene CR42435 CR42435 16-Dec-15 2015_12 FBgn0001844 l(1)ts1891 lethal (1) ts1891 http://flybase.net/reports/FBgn0001844.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0035216 CG9168 http://flybase.net/reports/FBgn0035216.html protein_coding_gene 0003824=catalytic activity "0008152=metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space gi23092768 "IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG9168 16-Dec-15 2015_12 viable FBgn0267171 CR45611 http://flybase.net/reports/FBgn0267171.html non_protein_coding_gene CR45611 16-Dec-15 2015_12 FBgn0019907 anon-14Bc anon-14Bc http://flybase.net/reports/FBgn0019907.html gene unnamed 16-Dec-15 2015_12 FBgn0262852 CR43216 http://flybase.net/reports/FBgn0262852.html pseudogene_attribute "noncoding_23161, noncoding_23159" CR43216 16-Dec-15 2015_12 FBgn0052752 CG32752 http://flybase.net/reports/FBgn0052752.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262203 mir-967 mir-967 stem loop http://flybase.net/reports/FBgn0262203.html miRNA_gene "CR42910, dme-mir-967, miR-967" CR42910 16-Dec-15 2015_12 viable FBgn0002293 l(3)80Fd lethal (3) 80Fd http://flybase.net/reports/FBgn0002293.html gene "l(3)Lh5, l5B, 80Fd" 16-Dec-15 2015_12 lethal FBgn0029032 l(2)R209 lethal (2) R209 http://flybase.net/reports/FBgn0029032.html gene R209 16-Dec-15 2015_12 "lethal,recessive" FBgn0067052 Rab9D Rab at 9D http://flybase.net/reports/FBgn0067052.html "FBgn0046864, FBgn0052678" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport" "0031982=vesicle, 0005886=plasma membrane" "Rab9D, unnamed, CG32678, Rab GTPase 9D, anon-AE003451.1" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG32678 16-Dec-15 2015_12 "viable,fertile" DRSC19853 K -0.173170085 -0.51929645 -0.432503261 0.179406866 -0.093187044 -1.988927987 FBgn0001082 Fum Fumarase http://flybase.net/reports/FBgn0001082.html gene 0004333=fumarate hydratase activity "Fuh, fumarase, FUM, Fumarate hydratase" 16-Dec-15 2015_12 electrophoretic variant FBgn0015572 ë±-Est4 ë±-Esterase-4 http://flybase.net/reports/FBgn0015572.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "DmalphaE4, alpha-Est4, C, fragment C, aE4, CG1082, FBgn0015572, alphaE4" "IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG1082 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" viable FBgn0003389 she sherry http://flybase.net/reports/FBgn0003389.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0264405 FCG-H http://flybase.net/reports/FBgn0264405.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0265651 CR44458 http://flybase.net/reports/FBgn0265651.html non_protein_coding_gene lincRNA.316 CR44458 16-Dec-15 2015_12 FBgn0043475 micropia\gag gag http://flybase.net/reports/FBgn0043475.html transposable_element_gene 16-Dec-15 2015_12 FBgn0036731 CG6333 http://flybase.net/reports/FBgn0036731.html protein_coding_gene CG6333 16-Dec-15 2015_12 viable FBgn0037085 Neu2 Neuroectoderm-expressed 2 http://flybase.net/reports/FBgn0037085.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "CG7204, Neu2" "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7204 16-Dec-15 2015_12 YPR186C(PZF1) WBGene00009448(zfp-2) embryonic stage | stage 5 ventral neurogenic region | restricted

viable FBgn0062629 Mod(var)1025 Mod(var)1025 http://flybase.net/reports/FBgn0062629.html gene 0006342=chromatin silencing 1025 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0082970 snoRNA:ë¬28S-3316c snoRNA:ë¬28S-3316c http://flybase.net/reports/FBgn0082970.html snoRNA_gene "Psi28S-3316c, CR34550, psi28S-3316c" CR34550 16-Dec-15 2015_12 FBgn0030361 CG1492 http://flybase.net/reports/FBgn0030361.html protein_coding_gene 0003840=gamma-glutamyltransferase activity 0006749=glutathione metabolic process "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000101=Gamma-glutamyltranspeptidase" CG1492 16-Dec-15 2015_12 YLR299W(ECM38) viable DRSC19605 E -0.182157153 -0.471713977 0.071032606 -2.206825679 -0.768534303 0.152363915 FBgn0067371 l(2)NC148 lethal (2) NC148 http://flybase.net/reports/FBgn0067371.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052687 CG32687 http://flybase.net/reports/FBgn0052687.html "FBgn0030209, FBgn0030210, FBgn0062948" protein_coding_gene "CG2143, CT7080, Cg32687, BcDNA:RH29237, CG2892, CT6984" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG32687 16-Dec-15 2015_12 ENSDARG00000063509(LOC564300) WBGene00021533(Y42G9A.3) ENSXETG00000018013(LRRC58) ENSMUSG00000034158(Lrrc58) ENSG00000163428(LRRC58) viable FBgn0024640 l(2)k12702 lethal (2) k12702 http://flybase.net/reports/FBgn0024640.html gene 127/2 16-Dec-15 2015_12 "lethal,recessive" FBgn0027119 l(?)rO127 lethal (?) rO127 http://flybase.net/reports/FBgn0027119.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0022024 l(2)k08931 lethal (2) k08931 http://flybase.net/reports/FBgn0022024.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003466 sp speck http://flybase.net/reports/FBgn0003466.html gene 16-Dec-15 2015_12 "visible,recessive,body color defective" FBgn0035583 CG13704 http://flybase.net/reports/FBgn0035583.html FBgn0063680 protein_coding_gene BcDNA:RE40159 CG13704 16-Dec-15 2015_12 viable FBgn0031176 CG1678 http://flybase.net/reports/FBgn0031176.html FBgn0063274 protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis BcDNA:GH04760 CG1678 16-Dec-15 2015_12 viable FBgn0032679 bsf bicoid stability factor http://flybase.net/reports/FBgn0032679.html protein_coding_gene 0003730=mRNA 3'-UTR binding "1903108=regulation of transcription from mitochondrial promoter, 0031426=polycistronic mRNA processing, 0034551=mitochondrial respiratory chain complex III assembly, 0070129=regulation of mitochondrial translation, 0033617=mitochondrial respiratory chain complex IV assembly, 0097222=mitochondrial mRNA polyadenylation, 1903862=positive regulation of oxidative phosphorylation, 0032981=mitochondrial respiratory chain complex I assembly" "0031673=H zone, 0034518=RNA cap binding complex, 0005739=mitochondrion, 0030018=Z disc, 0005737=cytoplasm" "Bicoid stability factor, DmLrpprc1, BSF, Bicoid Stabilization Factor, CG10302" IPR002885=Pentatricopeptide repeat CG10302 16-Dec-15 2015_12 ENSDARG00000043970(lrpprc) WBGene00015425(C04E6.11) ENSXETG00000009296(lrpprc) ENSMUSG00000024120(Lrpprc) ENSG00000138095(LRPPRC) "viable,fertile" FBgn0025508 l(2)59ABb lethal (2) 59ABb http://flybase.net/reports/FBgn0025508.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267162 CR45602 http://flybase.net/reports/FBgn0267162.html non_protein_coding_gene CR45602 16-Dec-15 2015_12 FBgn0259164 CG42269 http://flybase.net/reports/FBgn0259164.html "FBgn0035671, FBgn0035672" protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "CG6600, CG6596" "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG42269 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" FBgn0003125 pop popeye http://flybase.net/reports/FBgn0003125.html gene 16-Dec-15 2015_12 "male sterile,recessive,viable,male,reduced,visible" "eye,ommatidium,wing" FBgn0020898 Su(osk)E2 Suppressor of oskar E2 http://flybase.net/reports/FBgn0020898.html gene E2 16-Dec-15 2015_12 FBgn0000102 aperA abnormal proboscis extension reflex A http://flybase.net/reports/FBgn0000102.html gene 0007637=proboscis extension reflex 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive,behavior defective" FBgn0015416 l(1)15DFb lethal (1) 15DFb http://flybase.net/reports/FBgn0015416.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263004 CG43312 http://flybase.net/reports/FBgn0263004.html protein_coding_gene CG43312 16-Dec-15 2015_12 FBgn0051935 CG31935 http://flybase.net/reports/FBgn0051935.html "FBgn0031348, FBgn0031350" protein_coding_gene 0005096=GTPase activator activity 0043547=positive regulation of GTPase activity "CG7373, CG10870" IPR026147=Rab3 GTPase-activating protein catalytic subunit CG31935 16-Dec-15 2015_12 ENSDARG00000019828 WBGene00004317(rbg-1) ENSXETG00000000480(RAB3GAP1) ENSMUSG00000036104(Rab3gap1) ENSG00000115839(RAB3GAP1) "viable,fertile" DRSC00291 I 1.721827207 0.184901134 0.860447172 -0.404708244 -0.011526002 -0.205525264 FBgn0263096 CR43364 http://flybase.net/reports/FBgn0263096.html pseudogene_attribute CR43364 16-Dec-15 2015_12 FBgn0023091 dimm dimmed http://flybase.net/reports/FBgn0023091.html FBgn0032942 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity" "0061101=neuroendocrine cell differentiation, 0006355=regulation of transcription, DNA-templated, 0046887=positive regulation of hormone secretion, 0002793=positive regulation of peptide secretion, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "c929, Dimm, DIMMED, Mist 1-related, CG8667, DIMM, bHLHa16, dim, Dimmed, Mistr" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG8667 16-Dec-15 2015_12 "viable,fertile,lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye photoreceptor cell,rhabdomereGMR.PU" FBgn0036515 CG12304 http://flybase.net/reports/FBgn0036515.html protein_coding_gene 0017101=aminoacyl-tRNA synthetase multienzyme complex p38 "IPR010987=Glutathione S-transferase, C-terminal-like" CG12304 16-Dec-15 2015_12 ENSDARG00000018903(zgc:63976) ENSXETG00000027596(TNeu091c01.1) ENSMUSG00000029610(Aimp2) ENSG00000106305(AIMP2) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0060642 l(3)S084101b lethal (3) S084101b http://flybase.net/reports/FBgn0060642.html gene 0841/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0028022 l(3)S103909 lethal (3) S103909 http://flybase.net/reports/FBgn0028022.html gene 1039/09 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0039321 CG10550 http://flybase.net/reports/FBgn0039321.html protein_coding_gene "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG10550 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0265171 T:TM-shg Transmembrane domain of shg http://flybase.net/reports/FBgn0265171.html engineered_tag 16-Dec-15 2015_12 FBgn0027139 l(3)87ABa lethal (3) 87ABa http://flybase.net/reports/FBgn0027139.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0031102 CG15462 http://flybase.net/reports/FBgn0031102.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030830 CG5172 http://flybase.net/reports/FBgn0030830.html FBgn0062968 protein_coding_gene "CT16557, BcDNA:RH06401" CG5172 16-Dec-15 2015_12 DRSC19936 I 0.294965684 2.200949359 0.528468348 0.249105804 -1.470969945 -0.774451201 FBgn0002888 mus202 mutagen-sensitive 202 http://flybase.net/reports/FBgn0002888.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive,radiation sensitive" FBgn0038053 CG18549 http://flybase.net/reports/FBgn0038053.html protein_coding_gene "IPR010291=Ion channel regulatory protein, UNC-93, IPR020846=Major facilitator superfamily domain" CG18549 16-Dec-15 2015_12 ENSDARG00000041250(zgc:113380) "WBGene00010925(M153.2),WBGene00009485(F36G9.3),WBGene00017945(F31D5.2)" ENSXETG00000019492(et) ENSMUSG00000020818(Mfsd11) ENSG00000092931(MFSD11) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0001490 l(1)10Ba lethal (1) 10Ba http://flybase.net/reports/FBgn0001490.html gene "10Bc, l(1)GLM16, l(1)G16" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,polyphasic" FBgn0019795 l(1)100 lethal (1) 100 http://flybase.net/reports/FBgn0019795.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000094 Anp Andropin http://flybase.net/reports/FBgn0000094.html protein_coding_gene "0006962=male-specific antibacterial humoral response, 0032504=multicellular organism reproduction, 0006965=positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria, 0009617=response to bacterium, 0050830=defense response to Gram-positive bacterium" "0005576=extracellular region, 0005615=extracellular space" "k-9, Cec, CG1361, And, CEC, andropin" IPR000875=Cecropin CG1361 16-Dec-15 2015_12 adult stage | male ejaculatory duct

viable FBgn0011612 l(1)I33e27 lethal (1) I33e27 http://flybase.net/reports/FBgn0011612.html FBgn0010206 gene l(1)33e27 16-Dec-15 2015_12 lethal FBgn0260118 2L3120 http://flybase.net/reports/FBgn0260118.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0086658 snoRNA:ë¬28S-1180 snoRNA:ë¬28S-1180 http://flybase.net/reports/FBgn0086658.html "FBgn0083002, FBgn0065063, FBgn0053661" snoRNA_gene 0005730=nucleolus "CR33661, snoR535, Psi 28S-1180(SnoR535), chr2R:7107301..7107415, snoRNA:535, psi28s-1180, Dm-535" CR33661 16-Dec-15 2015_12 FBgn0017466 TfIIH-116 Transcription factor IIH-116kD http://flybase.net/reports/FBgn0017466.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TfIIH, TFIIH" 16-Dec-15 2015_12 FBgn0263629 mir-3643 mir-3643 stem loop http://flybase.net/reports/FBgn0263629.html "FBgn0262134, FBgn0263524" miRNA_gene CR43509 CR43509 16-Dec-15 2015_12 viable FBgn0001680 l(1)ESHS1 lethal (1) ESHS1 http://flybase.net/reports/FBgn0001680.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267253 CG32700 http://flybase.net/reports/FBgn0267253.html "FBgn0052700, FBgn0030134, FBgn0030135, FBgn0040934, FBgn0042222, FBgn0046791, FBgn0263508" protein_coding_gene "CG2994, CR43497, Tes89, CG18429, CG12651, BcDNA:GH19985, CG12652" CG32700 16-Dec-15 2015_12 FBgn0262736 Vha16-1 Vacuolar H+ ATPase 16kD subunit 1 http://flybase.net/reports/FBgn0262736.html "FBgn0004145, FBgn0011275, FBgn0015839, FBgn0033078, FBgn0044467, FBgn0046764, FBgn0086547" protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" "0033227=dsRNA transport, 0015992=proton transport, 0015991=ATP hydrolysis coupled proton transport, 0007476=imaginal disc-derived wing morphogenesis" "0000220=vacuolar proton-transporting V-type ATPase, V0 domain, 0045169=fusome, 0033181=plasma membrane proton-transporting V-type ATPase complex" "MRE15, EP2372, Ductin subunit C, c subunit, Vacuolar H[+]-ATPase c subunit, Vhac, ATP6V0C, mRNA-like ncRNA in embryogenesis 15, Ductin, V-ATPase, ductin, ductin, vacuolar H(+)-ATPase subunit C proteolipid, vha16, Vha16, Vha1, DucC, CG3161, BcDNA:SD02875, unnamed, Vacuolar H[+] ATPase subunit 16-1, Vacuolar H[+] ATPase 16kD subunit, vha16-1" "IPR002379=V-ATPase proteolipid subunit C-like domain, IPR000245=V-ATPase proteolipid subunit, IPR011555=V-ATPase proteolipid subunit C, eukaryotic" CG3161 16-Dec-15 2015_12 ENSDARG00000057853(atp6v0c) YEL027W(CUP5) WBGene00006912(vha-3) ENSXETG00000024442(atpv0c) ENSMUSG00000024121(Atp6v0c) ENSG00000185883(ATP6V0C) DRSC05020 E -0.052804946 -0.120237927 0.748986477 -1.836981377 -0.163276801 -0.660154995 FBgn0264646 ichor ichor http://flybase.net/reports/FBgn0264646.html gene 0060439=trachea morphogenesis ichorous 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0038752 CG4462 http://flybase.net/reports/FBgn0038752.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG4462 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0084421 l(3)S090114 l(3)S090114 http://flybase.net/reports/FBgn0084421.html gene 16-Dec-15 2015_12 FBgn0004476 Exh Epoxide hydrolase http://flybase.net/reports/FBgn0004476.html gene 0004301=epoxide hydrolase activity 0043231=intracellular membrane-bounded organelle "Epoxide hydratase, EH" 16-Dec-15 2015_12 FBgn0040559 CG14359 http://flybase.net/reports/FBgn0040559.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC14822 K -0.100329697 -0.158764521 0.777055153 -0.306254371 -1.622359899 -0.618809154 FBgn0085428 Nox NADPH oxidase http://flybase.net/reports/FBgn0085428.html "FBgn0034112, FBgn0034111" protein_coding_gene "0016175=superoxide-generating NADPH oxidase activity, 0005509=calcium ion binding" "0042554=superoxide anion generation, 0055114=oxidation-reduction process" "CG3896, CG15924, NOX-1, dNox, dnox, Nox1, NADPH oxidase, CG34399" "IPR002048=EF-hand domain, IPR013121=Ferric reductase, NAD binding domain, IPR029648=NADPH oxidase 5, IPR018247=EF-Hand 1, calcium-binding site, IPR013130=Ferric reductase transmembrane component-like domain, IPR011992=EF-hand domain pair, IPR017938=Riboflavin synthase-like beta-barrel, IPR013112=FAD-binding 8, IPR017927=Ferredoxin reductase-type FAD-binding domain" CG34399 16-Dec-15 2015_12 ENSXETG00000007819(NOX5) "ENSMUSG00000031257(Nox1),ENSMUSG00000015340(Cybb),ENSMUSG00000023802(Nox3),ENSMUSG00000030562(Nox4)" ENSG00000137808(SPESP1) "viable,visible" trichogen cell DRSC06596 K 0.29095809 0.989383219 0.180497155 0.434073305 1.759216109 1.310402486 FBgn0069911 CR40475 http://flybase.net/reports/FBgn0069911.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0025624 CG4025 http://flybase.net/reports/FBgn0025624.html FBgn0044709 protein_coding_gene 0005515=protein binding 0010506=regulation of autophagy 0005764=lysosome "EG:22E5.9, DRAM, anon-WO0140519.169" IPR019402=Frag1/DRAM/Sfk1 CG4025 16-Dec-15 2015_12 "ENSDARG00000044241(dram2),ENSDARG00000043569,ENSDARG00000045561(dram1)" WBGene00007878(C33A11.2) ENSXETG00000027990(Q5EAK8_XENTR) "ENSMUSG00000020057(Dram1),ENSMUSG00000027900(Dram2)" "ENSG00000156171(DRAM2),ENSG00000136048(DRAM1)" viable FBgn0261528 vainsE vainsE http://flybase.net/reports/FBgn0261528.html protein_coding_gene 16-Dec-15 2015_12 smell perception defective FBgn0261549 rdgA retinal degeneration A http://flybase.net/reports/FBgn0261549.html "FBgn0085373, FBgn0040930, FBgn0030069, FBgn0003217" protein_coding_gene "0019992=diacylglycerol binding, 0004143=diacylglycerol kinase activity" "0007601=visual perception, 0007015=actin filament organization, 0007205=protein kinase C-activating G-protein coupled receptor signaling pathway, 0007602=phototransduction, 0016059=deactivation of rhodopsin mediated signaling, 0006654=phosphatidic acid biosynthetic process, 0006661=phosphatidylinositol biosynthetic process, 0007605=sensory perception of sound, 0046834=lipid phosphorylation, 0043052=thermotaxis, 0045494=photoreceptor cell maintenance, 0007608=sensory perception of smell, 0016056=rhodopsin mediated signaling pathway, 0016310=phosphorylation, 0035556=intracellular signal transduction" "0005875=microtubule associated complex, 0016020=membrane" "CG12660, diacylglycerol kinase, receptor degeneration A, CG42667, DGK2, x35, CG34344, Retinal Degeneration A, DAG kinase, dDGK2, DAG-kinase, DGK, receptor-degeneration-I, CG15352, dgk-5, RDGA, CG10966" "IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000756=Diacylglycerol kinase, accessory domain, IPR001206=Diacylglycerol kinase, catalytic domain" CG42667 16-Dec-15 2015_12 "ENSDARG00000014439,ENSDARG00000063578" WBGene00019428(dgk-5) ENSXETG00000001956(DGKZ) "ENSMUSG00000038665(Dgki),ENSMUSG00000040479" "ENSG00000157680(DGKI),ENSG00000149091(DGKZ)" adult stage " eye

, adult head

" FBgn0085085 C30 C30 http://flybase.net/reports/FBgn0085085.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0061124 l(3)S003831b lethal (3) S003831b http://flybase.net/reports/FBgn0061124.html gene 0038/31 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0003903 twt twirled tips http://flybase.net/reports/FBgn0003903.html gene 16-Dec-15 2015_12 "male sterile,viable,male,poor,visible" wing FBgn0024634 l(2)k13914 lethal (2) k13914 http://flybase.net/reports/FBgn0024634.html gene 139/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0036176 CG7377 http://flybase.net/reports/FBgn0036176.html protein_coding_gene HDC09644 CG7377 16-Dec-15 2015_12 DRSC10830 K -0.451229146 -0.177714508 0.254978093 -0.060171851 1.60108159 0.08202611 FBgn0037677 CG12951 http://flybase.net/reports/FBgn0037677.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP87 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG12951 16-Dec-15 2015_12 "ENSMUSG00000030713(Klk7),ENSMUSG00000064023(Klk8),ENSMUSG00000054046(Klk13),ENSMUSG00000067616(Klk11),ENSMUSG00000074155(Klk5),ENSMUSG00000044737(Klk14),ENSMUSG00000044485(Klk1b11),ENSMUSG00000059042(Klk1b9),ENSMUSG00000044430(Klk12),ENSMUSG00000055193(Klk15),ENSMUSG00000050063(Klk6),ENSMUSG00000066515(Klk1b3),ENSMUSG00000063177(Klk1b27),ENSMUSG00000063133(Klk1b1),ENSMUSG00000063903(Klk1),ENSMUSG00000063713(Klk1b24),ENSMUSG00000066516(Klk1b21),ENSMUSG00000030693(Klk10),ENSMUSG00000053719(Klk1b26),ENSMUSG00000060177(Klk1b22),ENSMUSG00000066513(Klk1b4),ENSMUSG00000066512(Klk1b5),ENSMUSG00000063089(Klk1b8),ENSMUSG00000006948(Klk4),ENSMUSG00000047884(Klk9),ENSMUSG00000038968(Klk1b16)" "ENSG00000167759(KLK13),ENSG00000167757(KLK11),ENSG00000129455(KLK8),ENSG00000167755(KLK6),ENSG00000129437(KLK14),ENSG00000167754(KLK5),ENSG00000167751(KLK2),ENSG00000142515(KLK3),ENSG00000174562(KLK15),ENSG00000213022(KLK9),ENSG00000169035(KLK7),ENSG00000167748(KLK1),ENSG00000186474(KLK12),ENSG00000167749(KLK4),ENSG00000129451(KLK10)" viable FBgn0037844 CG4570 http://flybase.net/reports/FBgn0037844.html protein_coding_gene "0003677=DNA binding, 0004803=transposase activity" "0006313=transposition, DNA-mediated, 0015074=DNA integration" "IPR002492=Transposase, Tc1-like" CG4570 16-Dec-15 2015_12 viable DRSC15602 I 0.575526501 1.997074849 0.827526756 0.383149066 -0.453905845 0.23599162 FBgn0003293 rta reduced tarsi http://flybase.net/reports/FBgn0003293.html gene 16-Dec-15 2015_12 "visible,male sterile,viable,poor" "eye,wing,macrochaeta,tarsal segment" FBgn0267320 CR45756 http://flybase.net/reports/FBgn0267320.html non_protein_coding_gene lincRNA.587 CR45756 16-Dec-15 2015_12 FBgn0051943 tRNA:CR31943 transfer RNA:CR31943 http://flybase.net/reports/FBgn0051943.html FBgn0060105 tRNA_gene 0033428=CAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002638.trna9-GlnCTG, chr2L.trna2-GlnCTG, CR31943, tRNA:Q:CTG:AE002638-d" CR31943 16-Dec-15 2015_12 FBgn0022980 rrpA reduced receptor potential A http://flybase.net/reports/FBgn0022980.html gene 16-Dec-15 2015_12 FBgn0013530 l(2)ry28 lethal (2) ry28 http://flybase.net/reports/FBgn0013530.html gene "l(2)28, unnamed" 16-Dec-15 2015_12 lethal FBgn0085680 CG41545 http://flybase.net/reports/FBgn0085680.html FBan0041545 protein_coding_gene 16-Dec-15 2015_12 FBgn0038079 NijC Ninjurin C http://flybase.net/reports/FBgn0038079.html protein_coding_gene "0007155=cell adhesion, 0042246=tissue regeneration" 0016021=integral component of membrane "CG14394, NijC, Ninjurin C" IPR007007=Ninjurin CG14394 16-Dec-15 2015_12 ENSDARG00000070233 ENSXETG00000015640(ninj1) "ENSMUSG00000037966(Ninj1),ENSMUSG00000041377(Ninj2)" "ENSG00000171840(NINJ2),ENSG00000131669(NINJ1)" viable FBgn0033951 CG10139 http://flybase.net/reports/FBgn0033951.html protein_coding_gene CG10139 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0042205 CG18764 http://flybase.net/reports/FBgn0042205.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like" CG18764 16-Dec-15 2015_12 WBGene00004335(ref-2) viable FBgn0038651 CG14299 http://flybase.net/reports/FBgn0038651.html protein_coding_gene "0046331=lateral inhibition, 0006914=autophagy" IPR029651=Ectopic P granules protein 5 CG14299 16-Dec-15 2015_12 WBGene00016968(C56C10.12) ENSMUSG00000039840(5430411K18Rik) ENSG00000152223(EPG5) "viable,visible" chaeta DRSC14778 I -1.960208172 -0.179971839 -1.031354948 -0.216407363 0.299610992 -0.307584695 FBgn0000869 fs(1)M64 female sterile (1) M64 http://flybase.net/reports/FBgn0000869.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0001112 Gld Glucose dehydrogenase http://flybase.net/reports/FBgn0001112.html protein_coding_gene "0004344=glucose dehydrogenase activity, 0016614=oxidoreductase activity, acting on CH-OH group of donors, 0050660=flavin adenine dinucleotide binding" "0046693=sperm storage, 0042335=cuticle development, 0006006=glucose metabolic process, 0055114=oxidation-reduction process, 0008364=pupal chitin-based cuticle development" 0005576=extracellular region "Go, GDH, gld, GLD, CG1152, l(3)84Cg, glucose oxidase, Glucose oxidase, glucose dehydrogenase" "IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG1152 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) " larval stage--pupal stage , adult stage | male " ejaculatory duct

"viable,fertile,wild-type,lethal,electrophoretic variant,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0267408 AOX1 Aldehyde oxidase 1 http://flybase.net/reports/FBgn0267408.html "FBgn0038347, FBgn0003120" protein_coding_gene "0004732=pyridoxal oxidase activity, 0005506=iron ion binding, 0050660=flavin adenine dinucleotide binding, 0051537=2 iron, 2 sulfur cluster binding, 0009055=electron carrier activity, 0016614=oxidoreductase activity, acting on CH-OH group of donors" "0055114=oxidation-reduction process, 0042817=pyridoxal metabolic process" "LPO, CG18522, DmAO1, lpo, Po, low-pyridoxal-oxidase, PO, CT42272, Pyridoxal oxidase" "IPR008274=Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR016208=Aldehyde oxidase/xanthine dehydrogenase, IPR002346=Molybdopterin dehydrogenase, FAD-binding, IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR002888=[2Fe-2S]-binding, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR016166=FAD-binding, type 2, IPR000674=Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR012675=Beta-grasp domain, IPR005107=CO dehydrogenase flavoprotein, C-terminal" CG18522 16-Dec-15 2015_12 FBgn0263263 fus2 http://flybase.net/reports/FBgn0263263.html gene 0008406=gonad development SGP cluster fusion defects 2 16-Dec-15 2015_12 "gonad,gonadal sheath proper primordium" FBgn0032810 CG13077 http://flybase.net/reports/FBgn0032810.html protein_coding_gene 0016021=integral component of membrane "IPR006593=Cytochrome b561/ferric reductase transmembrane, IPR004877=Cytochrome b561 domain" CG13077 16-Dec-15 2015_12 "ENSDARG00000044114(cyb561d2),ENSDARG00000055295(cyb561d1)" ENSXETG00000025206(Cyb561d2) "ENSG00000174151(CYB561D1),ENSG00000114395(CYB561D2)" DRSC02181 K -1.386450746 0.270070209 0.882256616 -0.032382211 1.65907269 1.404041946 FBgn0040357 CG14624 http://flybase.net/reports/FBgn0040357.html FBgn0029569 protein_coding_gene 0046331=lateral inhibition "BACR42I17.9, EG:BACR42I17.9" CG14624 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" DRSC25253 K 0.110635356 0.769433935 0.456507648 -0.003715191 0.460723883 1.728989613 FBgn0028421 Kap3 Kinesin associated protein 3 http://flybase.net/reports/FBgn0028421.html FBgn0030287 protein_coding_gene "0019894=kinesin binding, 0005515=protein binding, 0003777=microtubule motor activity" "0007018=microtubule-based movement, 0035058=nonmotile primary cilium assembly, 0030951=establishment or maintenance of microtubule cytoskeleton polarity, 0007608=sensory perception of smell, 0007288=sperm axoneme assembly, 0008089=anterograde axon cargo transport, 0007605=sensory perception of sound" "0005871=kinesin complex, 0016939=kinesin II complex" "KAP3, kinesin-2, DmKAP, Kinesin-2, dKAP3, kap3, KAP, CG11759, Kinesin-associated protein 3, kinesin accessory protein, DmKap, Kinesin II accessory protein, Kap" "IPR016024=Armadillo-type fold, IPR008658=Kinesin-associated protein 3, IPR011989=Armadillo-like helical" CG11759 16-Dec-15 2015_12 "ENSDARG00000006862(kifap3),ENSDARG00000008639(zgc:101095)" WBGene00002182(kap-1) ENSXETG00000004733(KIFAP3) ENSMUSG00000026585(Kifap3) ENSG00000075945(KIFAP3) "uncoordinated,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,auditory perception defective,neuroanatomy defective,lethal,female,locomotor behavior defective,viable" "Johnston's organ & scolopidial cilium,sensillum trichodeum of antennal segment 3,sensillum basiconicum of antennal segment 3,labellar taste bristle,cilium" FBgn0003488 sprw spread wings http://flybase.net/reports/FBgn0003488.html gene spr 16-Dec-15 2015_12 "male sterile,female sterile" wing FBgn0013456 fs(2)neo4 fs(2)neo4 http://flybase.net/reports/FBgn0013456.html gene unnamed 16-Dec-15 2015_12 "female sterile,lethal,maternal effect" FBgn0065090 snmRNA:558 small non-messenger RNA 558 http://flybase.net/reports/FBgn0065090.html non_protein_coding_gene Dm-558 16-Dec-15 2015_12 FBgn0033996 CG11807 http://flybase.net/reports/FBgn0033996.html protein_coding_gene 0035091=phosphatidylinositol binding CT14564 "IPR001611=Leucine-rich repeat, IPR001683=Phox homologous domain" CG11807 16-Dec-15 2015_12 ENSDARG00000043077(si:ch211-103f16.1) WBGene00008750(F13E9.1) viable FBgn0029746 CG15465 http://flybase.net/reports/FBgn0029746.html protein_coding_gene CG15465/CG6775 CG15465 16-Dec-15 2015_12 viable FBgn0050411 CG30411 http://flybase.net/reports/FBgn0050411.html FBgn0047180 protein_coding_gene BcDNA:RE06996 CG30411 16-Dec-15 2015_12 viable FBgn0039193 CG13613 http://flybase.net/reports/FBgn0039193.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG13613 16-Dec-15 2015_12 viable FBgn0051702 CG31702 http://flybase.net/reports/FBgn0051702.html FBan0031702 protein_coding_gene 0003677=DNA binding "0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter" 0016593=Cdc73/Paf1 complex "IPR031102=RNA polymerase-associated protein Rtf1, IPR004343=Plus-3 domain" CG31702 16-Dec-15 2015_12 DRSC03687 I 0.090913164 -1.807668958 -0.666848206 -0.453463609 -0.374582422 0.093253773 FBgn0052463 Tengl2 Testis EndoG-Like 2 http://flybase.net/reports/FBgn0052463.html FBgn0031404 protein_coding_gene "0004520=endodeoxyribonuclease activity, 0046872=metal ion binding, 0003676=nucleic acid binding" 0046331=lateral inhibition 0005739=mitochondrion "CG17006, CG32463" "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A, IPR018524=DNA/RNA non-specific endonuclease, active site" CG32463 16-Dec-15 2015_12 YJL208C(NUC1) ENSXETG00000025614(ENDOG) "viable,visible" chaeta FBgn0023214 edl ETS-domain lacking http://flybase.net/reports/FBgn0023214.html "FBgn0019696, FBgn0024241, FBgn0034373, FBgn0064196, FBgn0064197" protein_coding_gene "0005515=protein binding, 0043565=sequence-specific DNA binding, 0001191=RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription" "0051168=nuclear export, 0006355=regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated, 0042325=regulation of phosphorylation, 0009880=embryonic pattern specification, 0007423=sensory organ development, 0042461=photoreceptor cell development, 0042058=regulation of epidermal growth factor receptor signaling pathway, 0046578=regulation of Ras protein signal transduction" 0005634=nucleus "edl/mae, Edl, Mae, mae, EDL, modulator of the activity of Ets, CG15085, Ets-domain lacking, ets domain lacking, Ets domain lacking, ets-domain lacking, MAE, anon-WO02077276.2, l(2)k06602, anon-WO02077276.3" "IPR013761=Sterile alpha motif/pointed domain, IPR003118=Pointed domain" CG15085 16-Dec-15 2015_12 " larval stage | third instar ," " eye disc | restricted

, chordotonal organ precursor cell | subset

" "lethal,recessive,neuroanatomy defective,visible,increased cell death" "denticle belt & embryonic abdominal segment 3,embryonic ventral epidermis & embryonic abdominal segment 1,embryonic ventral epidermis & embryonic abdominal segment 2,embryonic ventral epidermis & embryonic abdominal segment 3,embryonic ventral epidermis & embryonic abdominal segment 4,denticle belt & embryonic abdominal segment 1,denticle belt & embryonic abdominal segment 2,denticle belt & embryonic abdominal segment 4,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,presumptive embryonic/larval central nervous system,ommatidium,eye,eye photoreceptor cell,ommatidial precursor cluster,dorsal appendage,wing,eye disc,mesothoracic tergum,drug conditional" FBgn0039030 CG6660 http://flybase.net/reports/FBgn0039030.html protein_coding_gene 0016021=integral component of membrane IPR002076=ELO family CG6660 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "viable,lethal - all die during larval stage" embryonic/larval spiracle | larval stage FBgn0011509 SrpRë_ Signal recognition particle receptor ë_ http://flybase.net/reports/FBgn0011509.html "FBgn0011516, FBgn0028478, FBgn0053162" protein_coding_gene "0005047=signal recognition particle binding, 0003924=GTPase activity" "0022008=neurogenesis, 0035293=chitin-based larval cuticle pattern formation, 0006614=SRP-dependent cotranslational protein targeting to membrane, 0008363=larval chitin-based cuticle development" "0012505=endomembrane system, 0005785=signal recognition particle receptor complex" "srpRbeta, SRbeta, Signal recognition particle receptor beta, Q9VSN9, Dm SRbeta, l(3)rL537, CG5950, BcDNA:GM04779, l(3)rK561, SrpRbeta, CG33162" "IPR019009=Signal recognition particle receptor, beta subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG33162 16-Dec-15 2015_12 ENSDARG00000030949(zgc:92746) YKL154W(SRP102) WBGene00011306(R186.3) ENSXETG00000011815(srprb) ENSMUSG00000032553(Srprb) ENSG00000144867(SRPRB) "lethal,recessive,neuroanatomy defective" "ventral nerve cord,peripheral nervous system,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,embryonic/larval neuroblast,ganglion mother cell" FBgn0259229 CG42329 http://flybase.net/reports/FBgn0259229.html "FBgn0031325, FBgn0031326" protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "CG14343, CG5156, CT16503" "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG42329 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" FBgn0000052 ade2 adenosine 2 http://flybase.net/reports/FBgn0000052.html protein_coding_gene 0004642=phosphoribosylformylglycinamidine synthase activity 0006189='de novo' IMP biosynthetic process "CG9127, pym, 153122_at, Ade2, Paics, adenosine2" "IPR017926=Glutamine amidotransferase, IPR010073=Phosphoribosylformylglycinamidine synthase, IPR016188=PurM-like, N-terminal domain, IPR010918=AIR synthase-related protein, C-terminal domain, IPR029062=Class I glutamine amidotransferase-like" CG9127 16-Dec-15 2015_12 ENSDARG00000003750(si:dkey-183n20.16) YGR061C(ADE6) WBGene00008654(F10F2.2) ENSMUSG00000020899(Pfas) ENSG00000178921(PFAS) "auxotroph,recessive,male sterile,visible,eye color defective,female sterile,viable,poor,lethal,male fertile,female fertile,melanotic necrosis,partially lethal - majority die,some die during pupal stage,increased cell death,lethal - all die before end of pupal stage" "wing vein,trichome of the posterior wing margin,macrochaeta,pigment cell,wing,posterior crossvein,ocellus pigment granule,dorsal row,ventral row,genitalia,wing disc" FBgn0024686 knax knobby axons http://flybase.net/reports/FBgn0024686.html gene 0001746=Bolwig's organ morphogenesis 16-Dec-15 2015_12 viable Bolwig nerve FBgn0032390 dgt2 dim ë_-tubulin 2 http://flybase.net/reports/FBgn0032390.html protein_coding_gene "0005515=protein binding, 0008017=microtubule binding" "0007052=mitotic spindle organization, 0031122=cytoplasmic microtubule organization" "0043234=protein complex, 0072687=meiotic spindle, 0005819=spindle, 0070652=HAUS complex, 0005875=microtubule associated complex" "Dgt2, dim gamma-tubulin 2, CG16969" CG16969 16-Dec-15 2015_12 DRSC02548 I 4.394329998 0.152605355 1.267882049 0.458646349 -0.520527722 -0.535886001 FBgn0014002 Pdi Protein disulfide isomerase http://flybase.net/reports/FBgn0014002.html protein_coding_gene 0003756=protein disulfide isomerase activity "0045454=cell redox homeostasis, 0006457=protein folding" "0005635=nuclear envelope, 0005791=rough endoplasmic reticulum, 0005788=endoplasmic reticulum lumen, 0005615=extracellular space, 0070732=spindle envelope, 0005783=endoplasmic reticulum, 0045169=fusome, 0048471=perinuclear region of cytoplasm, 0043025=neuronal cell body, 0005811=lipid particle, 0005737=cytoplasm, 0012505=endomembrane system, 0060187=cell pole" "Dpdi, Protein disulphide isomerase, protein disulfide isomerase, EP(3)1022, dpdi, protein-disulfide isomerase, Protein Disulfide Isomerase, CG6988, pdi, proline diisomerease, PDI, disulfide isomerase, protein disulphide isomerase" "IPR013766=Thioredoxin domain, IPR005788=Disulphide isomerase, IPR012336=Thioredoxin-like fold, IPR017937=Thioredoxin, conserved site, IPR005792=Protein disulphide isomerase" CG6988 16-Dec-15 2015_12 ENSDARG00000052589(p4hb) "YCL043C(PDI1),YDR518W(EUG1)" WBGene00003963(pdi-2) ENSXETG00000005405(p4hb) ENSMUSG00000025130(P4hb) ENSG00000185624(P4HB) "lethal,viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0035046 ND-19 NADH dehydrogenase (ubiquinone) 19 kDa subunit http://flybase.net/reports/FBgn0035046.html protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "RH23043p, NDUFA8, NADH-UBIQUINONE OXIDOREDUCTASE 19 KDA SUBUNIT, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, NADH ubiquinone oxidoreductase 19 kDa, NADH:ubiquinone oxidoreductase 19 kDa subunit, NUPM, CG3683, FBpp0072231" "IPR016680=NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8, IPR010625=CHCH" CG3683 16-Dec-15 2015_12 ENSDARG00000058041(ndufa8) WBGene00021849(Y54F10AM.5) ENSXETG00000016324(NDUFA8) ENSMUSG00000026895(Ndufa8) ENSG00000119421(NDUFA8) "viable,visible" "trichogen cell,mitochondrionple.PF" FBgn0023468 anon-52Db anon-52Db http://flybase.net/reports/FBgn0023468.html gene 16-Dec-15 2015_12 FBgn0065909 l(2)SH0184 lethal (2) SH0184 http://flybase.net/reports/FBgn0065909.html gene l(2)SH2 0184 16-Dec-15 2015_12 "lethal,recessive" FBgn0065725 l(2)SH0562 lethal (2) SH0562 http://flybase.net/reports/FBgn0065725.html gene l(2)SH2 0562 16-Dec-15 2015_12 "lethal,recessive" FBgn0038369 Arpc3A "Actin-related protein 2/3 complex, subunit 3A" http://flybase.net/reports/FBgn0038369.html protein_coding_gene "0003779=actin binding, 0005200=structural constituent of cytoskeleton" 0034314=Arp2/3 complex-mediated actin nucleation 0005885=Arp2/3 protein complex "CG4560, ARPC, Arpc3A, ARC-P21, Arpc3a" IPR007204=Actin-related protein 2/3 complex subunit 3 CG4560 16-Dec-15 2015_12 ENSDARG00000057882(arpc3) YLR370C(ARC18) WBGene00000203(arx-5) ENSXETG00000020940(ARPC3) ENSMUSG00000029465(Arpc3) ENSG00000111229(ARPC3) adult stage "viable,visible" "chaeta,supernumerary" FBgn0035630 CG10576 http://flybase.net/reports/FBgn0035630.html FBgn0046317 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0004177=aminopeptidase activity" "0008283=cell proliferation, 0007049=cell cycle, 0006355=regulation of transcription, DNA-templated" "BEST:CK00496, proliferation-associated protein" "IPR000994=Peptidase M24, structural domain, IPR004545=ErbB3-binding protein 1, IPR011991=Winged helix-turn-helix DNA-binding domain" CG10576 16-Dec-15 2015_12 "ENSDARG00000070657(pa2g4b),ENSDARG00000069967,ENSDARG00000039578(pa2g4a)" WBGene00021088(W08E12.7) ENSXETG00000009471(pa2g4) ENSMUSG00000025364(Pa2g4) ENSG00000170515(PA2G4) "viable,fertile" presumptive embryonic/larval muscle system FBgn0051324 CG31324 http://flybase.net/reports/FBgn0051324.html "FBgn0039414, FBgn0040603, FBgn0062912" protein_coding_gene "CG14557, CG14555, BcDNA:RH68619" CG31324 16-Dec-15 2015_12 viable FBgn0001995 mRpL4 mitochondrial ribosomal protein L4 http://flybase.net/reports/FBgn0001995.html FBgn0032584 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "CG5818, BG:DS02740.17, lethal(2)35Fe, L4, l(2)35Fe, l35Fe, Rpl4, mrpL4, l(2)k14608, mitochondrial ribosomal protein large subunit 4" "IPR013005=50S ribosomal protein uL4, IPR023574=Ribosomal protein L4 domain, IPR002136=Ribosomal protein L4/L1e" CG5818 16-Dec-15 2015_12 ENSDARG00000058824(zgc:110034) WBGene00020717(T23B12.2) ENSXETG00000022060(mrpl4) ENSMUSG00000003299(Mrpl4) ENSG00000105364(MRPL4) "lethal,recessive,visible,somatic clone,mitotic cell cycle defective,viable" "eye,somatic clone,eye disc,lens" FBgn0058130 CG40130 http://flybase.net/reports/FBgn0058130.html FBan0040130 protein_coding_gene 16-Dec-15 2015_12 FBgn0260344 GSd441 http://flybase.net/reports/FBgn0260344.html gene 16-Dec-15 2015_12 lethal FBgn0037250 CG1074 http://flybase.net/reports/FBgn0037250.html "FBan0001074, FBgn0062105" protein_coding_gene "0008168=methyltransferase activity, 0003676=nucleic acid binding" 0032259=methylation anon-WO0118547.308 "IPR000241=Putative RNA methylase domain, IPR016691=tRNA guanosine-2'-O-methyltransferase, TRM11, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR002052=DNA methylase, N-6 adenine-specific, conserved site" CG1074 16-Dec-15 2015_12 ENSDARG00000040033(trmt11) YOL124C(TRM11) WBGene00022107(Y71F9AL.1) ENSXETG00000011700(TRMT11) ENSMUSG00000019792(Trmt11) ENSG00000066651(TRMT11) viable FBgn0025138 su(RpII140Z36)S1 su(RpII140Z36)S1 http://flybase.net/reports/FBgn0025138.html gene Z36[S1] 16-Dec-15 2015_12 FBgn0265514 E(comt6)E32 http://flybase.net/reports/FBgn0265514.html gene Enhancer of comatose[6] E32 16-Dec-15 2015_12 FBgn0037385 glob3 globin 3 http://flybase.net/reports/FBgn0037385.html protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0019825=oxygen binding" 0015671=oxygen transport 0005737=cytoplasm "DmeGb3, CG14675" "IPR012292=Globin/Protoglobin, IPR009050=Globin-like, IPR000971=Globin" CG14675 16-Dec-15 2015_12 "viable,fertile" FBgn0001397 l(1)2Dg lethal (1) 2Dg http://flybase.net/reports/FBgn0001397.html gene "N3, l(1)N3, l(1)90" 16-Dec-15 2015_12 "lethal,recessive" FBgn0062536 anon-5187 anon-5187 http://flybase.net/reports/FBgn0062536.html gene 5187 16-Dec-15 2015_12 FBgn0003604 Su(var)3-13 Suppressor of variegation 3-13 http://flybase.net/reports/FBgn0003604.html gene Su-var(3)13 16-Dec-15 2015_12 "suppressor of variegation,dominant,lethal,recessive" FBgn0034869 CG13558 http://flybase.net/reports/FBgn0034869.html protein_coding_gene CG13558 16-Dec-15 2015_12 DRSC04196 K 0.089536904 -0.08729302 0.053414725 0.260902088 0.045184435 1.529522059 FBgn0002571 Mal-A3 Maltase A3 http://flybase.net/reports/FBgn0002571.html protein_coding_gene "0004558=alpha-1,4-glucosidase activity, 0003824=catalytic activity, 0043169=cation binding" "0006006=glucose metabolic process, 0005975=carbohydrate metabolic process" "CG8695, V, maltase, Larval visceral protein L, gene V, hdl cuticle gene cluster, mal_A3, lvpL, L, LvpL, Drome_A3" "IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR015902=Glycoside hydrolase, family 13, IPR013781=Glycoside hydrolase, catalytic domain" CG8695 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) " larval stage | early third instar larval stage , adult stage , larval stage | first instar , larval stage | second instar " organism

viable FBgn0000979 fs(2)HO192 female sterile (2) HO192 http://flybase.net/reports/FBgn0000979.html gene fs(2)192A 16-Dec-15 2015_12 "female sterile,recessive" ovary FBgn0265211 fs(2)Z2-965 http://flybase.net/reports/FBgn0265211.html gene 16-Dec-15 2015_12 female sterile FBgn0011266 srh short rhabdomeres http://flybase.net/reports/FBgn0011266.html gene 16-Dec-15 2015_12 FBgn0050449 tRNA:CR30449 transfer RNA:CR30449 http://flybase.net/reports/FBgn0050449.html FBgn0050221 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR30449, CR30221, chr2R.trna39-GluCTC" CR30449 16-Dec-15 2015_12 FBgn0013485 l(1)5P4 lethal (1) 5P4 http://flybase.net/reports/FBgn0013485.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0259954 CG42464 http://flybase.net/reports/FBgn0259954.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG42464 16-Dec-15 2015_12 ENSDARG00000069736 ENSXETG00000016886(SPINT3) "ENSMUSG00000074595(Wfdc6a),ENSMUSG00000070531(Wfdc6b),ENSMUSG00000017733(Spinlw1)" FBgn0024865 l(3)04836 lethal (3) 04836 http://flybase.net/reports/FBgn0024865.html gene 4836 16-Dec-15 2015_12 "lethal,recessive" FBgn0065877 l(2)SH0240 lethal (2) SH0240 http://flybase.net/reports/FBgn0065877.html gene l(2)SH2 0240 16-Dec-15 2015_12 "lethal,recessive" FBgn0259270 C832 http://flybase.net/reports/FBgn0259270.html gene 16-Dec-15 2015_12 visible wing FBgn0020662 E(spl)m8-HLH::E(spl)m5-HLH http://flybase.net/reports/FBgn0020662.html engineered_fusion_gene "E(spl)::HLHm5, E(spl)::E(spl)m5-HLH" 16-Dec-15 2015_12 FBgn0259437 EP-207 http://flybase.net/reports/FBgn0259437.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing margin,chaeta,ectopic" FBgn0051224 CG31224 http://flybase.net/reports/FBgn0051224.html "FBgn0038634, FBgn0038635, FBgn0069189" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0005634=nucleus "CG17796, CG7696, l(3)c00083, unnamed, lethal (3) c00083" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG31224 16-Dec-15 2015_12 "ENSDARG00000036698(si:dkey-109n11.2),ENSDARG00000014825" WBGene00012385(Y5F2A.4) ENSG00000066422(ZBTB11) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC16290 K -0.531553635 -0.13698214 0.488603924 1.492804615 -1.858871294 -0.89770294 FBgn0046660 anon-38C.45 anon-38C.45 http://flybase.net/reports/FBgn0046660.html gene 38C.45 16-Dec-15 2015_12 FBgn0060789 l(3)S059403 lethal (3) S059403 http://flybase.net/reports/FBgn0060789.html gene 0594/03 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014937 anon-92Ec anon-92Ec http://flybase.net/reports/FBgn0014937.html gene mic 16-Dec-15 2015_12 FBgn0085234 CG34205 http://flybase.net/reports/FBgn0085234.html protein_coding_gene CG13504 CG34205 16-Dec-15 2015_12 FBgn0060317 l(3)S147406a lethal (3) S147406a http://flybase.net/reports/FBgn0060317.html gene "1474/06, l(3)s147406" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0065251 l(2)SH2120 lethal (2) SH2120 http://flybase.net/reports/FBgn0065251.html gene l(2)SH2 2120 16-Dec-15 2015_12 "lethal,recessive" FBgn0026013 WC1 WC1 http://flybase.net/reports/FBgn0026013.html gene 1(1)WC1 16-Dec-15 2015_12 "lethal,recessive" "embryonic epidermis,embryonic head" FBgn0065241 l(2)SH2154 lethal (2) SH2154 http://flybase.net/reports/FBgn0065241.html gene l(2)SH2 2154 16-Dec-15 2015_12 "lethal,recessive" FBgn0260935 Vps15 Vacuolar protein sorting 15 http://flybase.net/reports/FBgn0260935.html "FBgn0024225, FBgn0037663" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0034198=cellular response to amino acid starvation, 0016236=macroautophagy, 0002784=regulation of antimicrobial peptide production, 0006914=autophagy, 0006468=protein phosphorylation, 0016322=neuron remodeling" "0034271=phosphatidylinositol 3-kinase complex, class III, type I" "Vps15, dVps15, vps15, ird1, CG9746, dVps15/p150, immune response deficient 1, ird, Ird1, immune response-deficient 1" "IPR001680=WD40 repeat, IPR011989=Armadillo-like helical, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR016024=Armadillo-type fold, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR000719=Protein kinase domain, IPR019775=WD40 repeat, conserved site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR020472=G-protein beta WD-40 repeat" CG9746 16-Dec-15 2015_12 ENSDARG00000060469(pik3r4) YBR097W(VPS15) WBGene00014151(ZK930.1) ENSXETG00000002330() ENSMUSG00000032571(Pik3r4) ENSG00000196455(PIK3R4) FBgn0266593 CR45118 http://flybase.net/reports/FBgn0266593.html non_protein_coding_gene CR45118 16-Dec-15 2015_12 FBgn0262531 CG43085 http://flybase.net/reports/FBgn0262531.html protein_coding_gene CG43085 16-Dec-15 2015_12 FBgn0024706 anon-84Ab anon-84Ab http://flybase.net/reports/FBgn0024706.html gene unnamed 16-Dec-15 2015_12 FBgn0028074 l(3)S088501a lethal (3) S088501a http://flybase.net/reports/FBgn0028074.html gene "0885/01, l(3)S088501" 16-Dec-15 2015_12 "lethal,recessive" FBgn0032551 CG18636 http://flybase.net/reports/FBgn0032551.html "FBtr0080688, FBpp0080250" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "unnamed, SPH130" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG18636 16-Dec-15 2015_12 WBGene00006621(try-3) FBgn0029881 pigs pickled eggs http://flybase.net/reports/FBgn0029881.html protein_coding_gene 0008093=cytoskeletal adaptor activity "0030713=ovarian follicle cell stalk formation, 0007050=cell cycle arrest, 0045746=negative regulation of Notch signaling pathway, 0030707=ovarian follicle cell development" "0015629=actin cytoskeleton, 0005881=cytoplasmic microtubule" CG3973 "IPR001715=Calponin homology domain, IPR003108=Growth-arrest-specific protein 2 domain, IPR029931=GAS2-like protein 1" CG3973 16-Dec-15 2015_12 "ENSXETG00000016415(GAS2L1),ENSXETG00000013478(GAS2L2)" ENSMUSG00000020686(Gas2l2) "viable,flightless,partially lethal - majority live,female sterile,fertile" "indirect flight muscle,ovary,interfollicle cell,female germline stem cell,supernumerary,nurse cell ring canal,germarium,egg chamber,somatic clone,polar follicle cell,germarium cap cell,follicle cell" FBgn0024619 meso4 meso4 http://flybase.net/reports/FBgn0024619.html FBgn0024479 gene Clone4 16-Dec-15 2015_12 FBgn0037891 CG5214 http://flybase.net/reports/FBgn0037891.html protein_coding_gene 0004149=dihydrolipoyllysine-residue succinyltransferase activity "0007406=negative regulation of neuroblast proliferation, 0045333=cellular respiration, 0006099=tricarboxylic acid cycle" "0005875=microtubule associated complex, 0005811=lipid particle, 0009353=mitochondrial oxoglutarate dehydrogenase complex" alpha-KGDHC "IPR000089=Biotin/lipoyl attachment, IPR006255=Dihydrolipoamide succinyltransferase, IPR001078=2-oxoacid dehydrogenase acyltransferase, catalytic domain, IPR023213=Chloramphenicol acetyltransferase-like domain, IPR011053=Single hybrid motif, IPR003016=2-oxo acid dehydrogenase, lipoyl-binding site" CG5214 16-Dec-15 2015_12 ENSDARG00000014230(dlst) YDR148C(KGD2) WBGene00020950(W02F12.5) ENSXETG00000013264(dlst) ENSMUSG00000004789(Dlst) ENSG00000119689(DLST) "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0028042 l(3)S098916 lethal (3) S098916 http://flybase.net/reports/FBgn0028042.html gene 0989/16 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026409 Mpcp Mitochondrial phosphate carrier protein http://flybase.net/reports/FBgn0026409.html FBgn0010721 protein_coding_gene "0022857=transmembrane transporter activity, 0015114=phosphate ion transmembrane transporter activity" "0006839=mitochondrial transport, 0048190=wing disc dorsal/ventral pattern formation, 0006817=phosphate ion transport" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane, 0005811=lipid particle, 0005739=mitochondrion, 0005740=mitochondrial envelope" "MPCP, Mcpc, Mitochondrial phophate carrier protein, mitochondrial proton/phosphate symporter, CG4994, PpsM, l(3)00564" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG4994 16-Dec-15 2015_12 "ENSDARG00000025566(slc25a3),ENSDARG00000027424(slc25a3l)" YER053C(PIC2) "WBGene00008505(F01G4.6),WBGene00016358(C33F10.12),WBGene00011493(T05F1.8)" ENSXETG00000018767(SLC25A3) ENSMUSG00000061904(Slc25a3) ENSG00000075415(SLC25A3) "lethal,recessive,viable,visible" "mesothoracic leg sensillum,metathoracic leg sensillum,prothoracic leg sensillum,antennal sense organ,trichogen cell" FBgn0037260 Mur82C Mucin related 82C http://flybase.net/reports/FBgn0037260.html FBan0012586 protein_coding_gene 0005201=extracellular matrix structural constituent 0031012=extracellular matrix "CG12586, Mur82C" CG12586 16-Dec-15 2015_12 viable DRSC12011 IE -0.952939843 -2.369737312 -0.526836068 -4.952584323 -0.347196467 -0.336546737 FBgn0000681 flrdD flight reduced D http://flybase.net/reports/FBgn0000681.html gene 0007629=flight behavior 16-Dec-15 2015_12 "flightless,cold sensitive,jumping defective,flight defective" FBgn0065169 l(3)SH029 lethal (3) SH029 http://flybase.net/reports/FBgn0065169.html gene l(2)SH3 029 16-Dec-15 2015_12 "lethal,recessive" FBgn0264719 CR43987 http://flybase.net/reports/FBgn0264719.html non_protein_coding_gene lincRNA.612 CR43987 16-Dec-15 2015_12 FBgn0001871 l(1)Xi08 lethal (1) Xi08 http://flybase.net/reports/FBgn0001871.html gene 16-Dec-15 2015_12 FBgn0250825 CG34241 http://flybase.net/reports/FBgn0250825.html "FBgn0085270, FBgn0045122, FBgn0045138, FBgn0045328" protein_coding_gene "NEST:bs31h06, NEST:bs11f11, NEST:bs29g03" CG34241 16-Dec-15 2015_12 FBgn0262368 mir-282 mir-282 stem loop http://flybase.net/reports/FBgn0262368.html "FBgn0067709, FBgn0262173" miRNA_gene "0048190=wing disc dorsal/ventral pattern formation, 0008340=determination of adult lifespan" "mir-282-RA, 282, mir-282, mir282, dme-mir-282, dme-mir-276a, miR-282, CR42880, CR33598, miR282" CR42880 16-Dec-15 2015_12 "viable,visible,partially lethal - majority die,short lived,female semi-sterile,female fertile,germline clone,lethal - all die during second instar larval stage,lethal" "wing vein,ectopic,germarium" FBgn0010406 RNaseX25 Ribonuclease X25 http://flybase.net/reports/FBgn0010406.html "FBtr0076752, FBpp0076469" protein_coding_gene "0004521=endoribonuclease activity, 0033897=ribonuclease T2 activity, 0004540=ribonuclease activity, 0003723=RNA binding" "0006401=RNA catabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "CG8194, DmRNase-X25, DmRNase-66B, acid RNase" "IPR018188=Ribonuclease T2, active site, IPR001568=Ribonuclease T2-like" CG8194 16-Dec-15 2015_12 ENSDARG00000036282 WBGene00019624(K10C9.3) ENSXETG00000016219() "ENSMUSG00000073469,ENSMUSG00000079724(Rnaset2b)" ENSG00000026297(RNASET2) viable FBgn0065969 l(2)SH0006 lethal (2) SH0006 http://flybase.net/reports/FBgn0065969.html gene l(2)SH2 0006 16-Dec-15 2015_12 "lethal,recessive" FBgn0039010 CG4907 http://flybase.net/reports/FBgn0039010.html protein_coding_gene 0016740=transferase activity 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane "IPR017852=GPI ethanolamine phosphate transferase 1, C-terminal, IPR007070=GPI ethanolamine phosphate transferase 1, IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG4907 16-Dec-15 2015_12 YKL165C(MCD4) WBGene00021840(Y54E10BR.1) viable FBgn0053354 5SrRNA:CR33354 5SrRNA:CR33354 http://flybase.net/reports/FBgn0053354.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33354 CR33354 16-Dec-15 2015_12 FBgn0265141 Ir47b Ionotropic receptor 47b http://flybase.net/reports/FBgn0265141.html pseudogene_attribute "CR44210, DmelIR47b" CR44210 16-Dec-15 2015_12 FBgn0014126 ax axed http://flybase.net/reports/FBgn0014126.html gene 16-Dec-15 2015_12 "visible,recessive" thorax FBgn0005343 Rst(1)mth Resistance to malathion http://flybase.net/reports/FBgn0005343.html gene Resistance (1) malathion 16-Dec-15 2015_12 FBgn0004760 l(3)89Ca lethal (3) 89Ca http://flybase.net/reports/FBgn0004760.html gene 16-Dec-15 2015_12 lethal FBgn0033210 U2A U2A http://flybase.net/reports/FBgn0033210.html "FBgn0004136, FBgn0047086" protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division" "0030532=small nuclear ribonucleoprotein complex, 0005686=U2 snRNP, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "CG1406, l(2)43Ee, dU2A', U2A', lethal(2)43Ee, U2A-prime, u2a, BcDNA:RE56869" "IPR001611=Leucine-rich repeat, IPR003603=U2A'/phosphoprotein 32 family A, C-terminal" CG1406 16-Dec-15 2015_12 ENSDARG00000024651(zgc:101832) YPL213W(LEA1) WBGene00044076(sap-1) ENSXETG00000018743(SNRPA1) ENSMUSG00000030512(Snrpa1) "ENSG00000131876(SNRPA1),ENSG00000144158" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0020831 l(2)PW27 lethal (2) PW27 http://flybase.net/reports/FBgn0020831.html gene l(2)PW#27 16-Dec-15 2015_12 "lethal,recessive" FBgn0060901 l(3)S044006 lethal (3) S044006 http://flybase.net/reports/FBgn0060901.html gene "440/6, 0440/06" 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0002058 l(2)40Fc lethal (2) 40Fc http://flybase.net/reports/FBgn0002058.html gene "GroupVIII, 40Fc, l(2)EMS40-2, l(2Lh)Fc, unnamed, l(2)EMS40-01" 16-Dec-15 2015_12 "lethal,partially,recessive" "eye,wing" FBgn0267986 CR46253 http://flybase.net/reports/FBgn0267986.html non_protein_coding_gene CR46253 16-Dec-15 2015_12 FBgn0265041 CG44158 http://flybase.net/reports/FBgn0265041.html protein_coding_gene CG44158 16-Dec-15 2015_12 FBgn0032153 CG4537 http://flybase.net/reports/FBgn0032153.html protein_coding_gene 0030165=PDZ domain binding 0031122=cytoplasmic microtubule organization 0030425=dendrite "IPR019367=PDZ-binding protein, CRIPT" CG4537 16-Dec-15 2015_12 ENSDARG00000045093(cript) WBGene00044614(C36B1.14) ENSXETG00000022737(CRIPT) ENSMUSG00000024146(Cript) ENSG00000119878(CRIPT) FBgn0029663 CG10804 http://flybase.net/reports/FBgn0029663.html protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity" 0006836=neurotransmitter transport 0016021=integral component of membrane IPR000175=Sodium:neurotransmitter symporter CG10804 16-Dec-15 2015_12 "viable,planar polarity defective" FBgn0015465 l(2)37Dm lethal (2) 37Dm http://flybase.net/reports/FBgn0015465.html gene l(2)E12 16-Dec-15 2015_12 "lethal,recessive" FBgn0005064 fs(2)OW204 female sterile (2) OW204 http://flybase.net/reports/FBgn0005064.html gene 16-Dec-15 2015_12 FBgn0030622 CG9101 http://flybase.net/reports/FBgn0030622.html protein_coding_gene IPR009069=Cysteine alpha-hairpin motif superfamily CG9101 16-Dec-15 2015_12 FBgn0031440 CG15395 http://flybase.net/reports/FBgn0031440.html protein_coding_gene 0007067=mitotic nuclear division "0005874=microtubule, 0005819=spindle" IPR009675=TPX2 CG15395 16-Dec-15 2015_12 viable FBgn0264573 CR43945 http://flybase.net/reports/FBgn0264573.html non_protein_coding_gene lincRNA.637 CR43945 16-Dec-15 2015_12 FBgn0033376 CG8777 http://flybase.net/reports/FBgn0033376.html protein_coding_gene 0000956=nuclear-transcribed mRNA catabolic process "ski3, SKI3" "IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR013105=Tetratricopeptide repeat 2" CG8777 16-Dec-15 2015_12 YPR189W(SKI3) ENSXETG00000013370(TTC37) ENSMUSG00000033991(Ttc37) ENSG00000198677(TTC37) FBgn0001597 l(1)CP7 lethal (1) CP7 http://flybase.net/reports/FBgn0001597.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0017362 l(3)89Bt lethal (3) 89Bt http://flybase.net/reports/FBgn0017362.html gene l(3)89Br 16-Dec-15 2015_12 partially lethal - majority die FBgn0038339 CG6118 http://flybase.net/reports/FBgn0038339.html protein_coding_gene 0007052=mitotic spindle organization "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG6118 16-Dec-15 2015_12 lethal FBgn0260625 d00627 http://flybase.net/reports/FBgn0260625.html gene 16-Dec-15 2015_12 visible wing FBgn0034299 CG5757 http://flybase.net/reports/FBgn0034299.html protein_coding_gene "0009041=uridylate kinase activity, 0005524=ATP binding, 0004798=thymidylate kinase activity" "0006233=dTDP biosynthetic process, 0006235=dTTP biosynthetic process, 0006227=dUDP biosynthetic process" "0005737=cytoplasm, 0005634=nucleus" "IPR018094=Thymidylate kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR018095=Thymidylate kinase, conserved site" CG5757 16-Dec-15 2015_12 ENSDARG00000052103(dtymk) YJR057W(CDC8) WBGene00011272(R53.2) ENSXETG00000002980(dtymk) ENSMUSG00000026281(Dtymk) "ENSG00000215694,ENSG00000168393(DTYMK)" "viable,fertile" FBgn0262411 mir-92a mir-92a stem loop http://flybase.net/reports/FBgn0262411.html "FBgn0067682, FBgn0067335, FBgn0262248" miRNA_gene "0008258=head involution, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0035195=gene silencing by miRNA" "miR-92A, miR-92, CR42955, dme-mir-92a, mIR-92a, miR-92a, mir-92a, mir-92, CR33571" CR42955 16-Dec-15 2015_12 embryonic stage -- adult stage "visible,lethal" "wing,wing hair,wing sensillum,ectopic" FBgn0025122 su(RpII140Z36)S6 su(RpII140Z36)S6 http://flybase.net/reports/FBgn0025122.html gene Z36[S6] 16-Dec-15 2015_12 FBgn0016997 limbo limbo http://flybase.net/reports/FBgn0016997.html gene 0007411=axon guidance lio 16-Dec-15 2015_12 "viable,female fertile,male fertile" "lamina anlage,medulla anlage,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon" FBgn0264890 CR44081 http://flybase.net/reports/FBgn0264890.html non_protein_coding_gene CR44081 16-Dec-15 2015_12 FBgn0065258 l(2)SH2098 lethal (2) SH2098 http://flybase.net/reports/FBgn0065258.html gene l(2)SH2 2098 16-Dec-15 2015_12 "lethal,recessive" FBgn0037624 CG8223 http://flybase.net/reports/FBgn0037624.html FBgn0065014 protein_coding_gene 0005634=nucleus IPR011990=Tetratricopeptide-like helical domain CG8223 16-Dec-15 2015_12 ENSDARG00000039208(nasp) ENSXETG00000003498(nasp) ENSG00000132780(NASP) "viable,visible" trichogen cell FBgn0053198 pen-2 presenilin enhancer http://flybase.net/reports/FBgn0053198.html "FBgn0043531, FBgn0061488" protein_coding_gene "0070765=gamma-secretase complex, 0005770=late endosome, 0055037=recycling endosome, 0005886=plasma membrane" "Presenilin enhancer 2, anon-AE003800.1, dPen-2, unnamed, Pen-2, CG33198" "IPR019379=Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit" CG33198 16-Dec-15 2015_12 "ENSDARG00000068707,ENSDARG00000068698(psenen)" WBGene00003975(pen-2) ENSXETG00000017565(psenen) ENSMUSG00000036835(Psenen) ENSG00000205155(PSENEN) viable FBgn0026374 Rhp Rhophilin http://flybase.net/reports/FBgn0026374.html protein_coding_gene 0017049=GTP-Rho binding 0007165=signal transduction CG8497 "IPR004328=BRO1 domain, IPR001478=PDZ domain, IPR011072=HR1 rho-binding repeat" CG8497 16-Dec-15 2015_12 "ENSDARG00000052454,ENSDARG00000014577(rhpn2)" ENSXETG00000018271() "ENSMUSG00000030494(Rhpn2),ENSMUSG00000022580(Rhpn1)" "ENSG00000131941(RHPN2),ENSG00000158106(RHPN1)" "lethal,recessive,viable" FBgn0011594 fs(3)6284 fs(3)6284 http://flybase.net/reports/FBgn0011594.html gene 16-Dec-15 2015_12 female sterile ovary FBgn0004171 Mst98Cb Male-specific RNA 98Cb http://flybase.net/reports/FBgn0004171.html "FBgn0039575, FBgn0044584" protein_coding_gene 0007286=spermatid development 0036126=sperm flagellum "CG18396, anon-WO0140519.46, Mst98C, MST98Cb, Mst, mst(3)gl-13" CG18396 16-Dec-15 2015_12 DRSC22495 K -0.469181941 -0.297419183 -0.158950211 0.263174333 -1.801402851 -1.037328446 FBgn0034446 Arl6 ADP ribosylation factor-like 6 http://flybase.net/reports/FBgn0034446.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0006886=intracellular protein transport, 0007264=small GTPase mediated signal transduction, 0042384=cilium assembly" "0005929=cilium, 0005622=intracellular" "ARL6, BBS3, CG7735, A1ZBK9, Arl6" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006689=Small GTPase superfamily, ARF/SAR type, IPR006687=Small GTPase superfamily, SAR1-type, IPR024156=Small GTPase superfamily, ARF type, IPR005225=Small GTP-binding protein domain" CG7735 16-Dec-15 2015_12 ENSDARG00000032056(arl6) WBGene00000193(arl-6) ENSXETG00000026476(arl6) ENSMUSG00000022722(Arl6) ENSG00000113966(ARL6) "viable,fertile" FBgn0026402 NiPp1 Nuclear inhibitor of Protein phosphatase 1 http://flybase.net/reports/FBgn0026402.html FBgn0034178 protein_coding_gene "0008157=protein phosphatase 1 binding, 0003729=mRNA binding, 0004865=protein serine/threonine phosphatase inhibitor activity, 0004864=protein phosphatase inhibitor activity" "0035308=negative regulation of protein dephosphorylation, 0007411=axon guidance" "0005634=nucleus, 0016607=nuclear speck" "nipp1, NIPP-1Dm, CG8980, NIPP1, NiPp-1, Nuclear inhibitor of PP1, NIPP1Dm" "IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG8980 16-Dec-15 2015_12 "ENSDARG00000022430(zgc:63827),ENSDARG00000007186(LOC566830)" WBGene00015233(B0511.7) ENSXETG00000011507(ppp1r8) ENSMUSG00000028882(Ppp1r8) ENSG00000117751(PPP1R8) "visible,lethal,mitotic cell cycle defective,locomotor rhythm defective,viable" "wing,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF,embryonic/larval optic neuropil,mitosis & nuclear chromosomearm.PS,indirect flight muscle,trichogen cell" FBgn0085371 CG34342 http://flybase.net/reports/FBgn0085371.html "FBgn0035609, FBgn0052422" protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "CG32422, CG10629" "IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding, IPR016040=NAD(P)-binding domain" CG34342 16-Dec-15 2015_12 FBgn0083956 CG34120 http://flybase.net/reports/FBgn0083956.html "FBan0001819, FBgn0031162, FBgn0052516, FBgn0063358" protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "CG32516, BcDNA:AT04622, CG1819" "IPR026082=ABC transporter A, ABCA, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain" CG34120 16-Dec-15 2015_12 viable FBgn0266128 82Y http://flybase.net/reports/FBgn0266128.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0011821 Pbp135 Phenylalkylamine-binding protein 135kD http://flybase.net/reports/FBgn0011821.html gene 0008145=phenylalkylamine binding 16-Dec-15 2015_12 adult stage adult head

FBgn0050025 CG30025 http://flybase.net/reports/FBgn0050025.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG30025 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" FBgn0267849 Syx7 Syntaxin 7 http://flybase.net/reports/FBgn0267849.html "FBgn0264632, FBgn0086377, FBgn0033583, FBgn0082601" protein_coding_gene "0005484=SNAP receptor activity, 0005515=protein binding, 0000149=SNARE binding" "0016081=synaptic vesicle docking, 0008285=negative regulation of cell proliferation, 0006906=vesicle fusion, 0035088=establishment or maintenance of apical/basal cell polarity, 0045807=positive regulation of endocytosis, 0060439=trachea morphogenesis, 0050678=regulation of epithelial cell proliferation, 0016192=vesicle-mediated transport, 0048227=plasma membrane to endosome transport, 0035073=pupariation, 0035264=multicellular organism growth, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0016334=establishment or maintenance of polarity of follicular epithelium, 0034058=endosomal vesicle fusion, 0007430=terminal branching, open tracheal system, 0007269=neurotransmitter secretion" "0005769=early endosome, 0031201=SNARE complex, 0005886=plasma membrane" "syx7/avl, Syntaxin7, braided, dSyntaxin-7, Syx, Avl, synatxin7/avalanche, Syntaxin, CG5081, Dm Syx7, syntaxin, avalanche, Avalanche, avl, DmSyx7, SYX7, FCP-C, dSyn7, Aval, syx7" "IPR006011=Syntaxin, N-terminal domain, IPR000727=Target SNARE coiled-coil homology domain, IPR010989=t-SNARE" CG5081 16-Dec-15 2015_12 "ENSDARG00000044605(LOC569124),ENSDARG00000010290(stx12),ENSDARG00000069173,ENSDARG00000069208(LOC100330434)" WBGene00009478(syx-7) "ENSXETG00000026515(STX7),ENSXETG00000014421(stx12)" "ENSMUSG00000019998(Stx7),ENSMUSG00000028879(Stx12)" "ENSG00000079950(STX7),ENSG00000117758(STX12)" FBgn0020562 anon-VII-C7 anon-VII-C7 http://flybase.net/reports/FBgn0020562.html gene 16-Dec-15 2015_12 Bolwig nerve FBgn0060515 l(3)S103807b lethal (3) S103807b http://flybase.net/reports/FBgn0060515.html gene 1038/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0085298 CG34269 http://flybase.net/reports/FBgn0085298.html protein_coding_gene CG34269 16-Dec-15 2015_12 FBgn0265863 CR44652 http://flybase.net/reports/FBgn0265863.html non_protein_coding_gene lincRNA.366 CR44652 16-Dec-15 2015_12 FBgn0029966 Ir7c Ionotropic receptor 7c http://flybase.net/reports/FBgn0029966.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity" 0009593=detection of chemical stimulus "0016021=integral component of membrane, 0016020=membrane" "ionotropic receptor 7c, IR7c, DmelIR7c, CG15324, CT35324" "IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG15324 16-Dec-15 2015_12 viable FBgn0082584 spy spermeye http://flybase.net/reports/FBgn0082584.html gene 0035092=sperm chromatin condensation 16-Dec-15 2015_12 FBgn0065851 l(2)SH0306 lethal (2) SH0306 http://flybase.net/reports/FBgn0065851.html gene l(2)SH2 0306 16-Dec-15 2015_12 "lethal,recessive" FBgn0035504 Teh4 tipE homolog 4 http://flybase.net/reports/FBgn0035504.html FBgn0046481 protein_coding_gene 0017080=sodium channel regulator activity 0002028=regulation of sodium ion transport 0016021=integral component of membrane "TEH4, anon-WO0172774.111, CG15003" CG15003 16-Dec-15 2015_12 viable FBgn0038234 mRpL11 mitochondrial ribosomal protein L11 http://flybase.net/reports/FBgn0038234.html FBgn0062439 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "BcDNA:RE67638, CG3351, L11, rpl-11" "IPR000911=Ribosomal protein L11/L12, IPR020783=Ribosomal protein L11, C-terminal, IPR020784=Ribosomal protein L11, N-terminal" CG3351 16-Dec-15 2015_12 ENSDARG00000013075(mrpl11) YNL185C(MRPL19) WBGene00015133(B0303.15) ENSXETG00000020574(mrpl11) ENSMUSG00000024902(Mrpl11) ENSG00000174547(MRPL11) "viable,visible,lethal,recessive" trichogen cell FBgn0031372 CG7295 http://flybase.net/reports/FBgn0031372.html protein_coding_gene IPR001199=Cytochrome b5-like heme/steroid binding domain CG7295 16-Dec-15 2015_12 viable DRSC00699 I -1.302535052 2.02421705 0.305493597 0.451989103 0.314887206 0.913530876 FBgn0017564 Nuc3 Nuclease 3 http://flybase.net/reports/FBgn0017564.html gene 0004518=nuclease activity 0005739=mitochondrion 16-Dec-15 2015_12 FBgn0069410 JJF175 JJF175 http://flybase.net/reports/FBgn0069410.html gene 16-Dec-15 2015_12 stress response defective FBgn0040724 CG16906 http://flybase.net/reports/FBgn0040724.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003734 torp torpid http://flybase.net/reports/FBgn0003734.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive,neurophysiology defective" FBgn0050087 CG30087 http://flybase.net/reports/FBgn0050087.html FBgn0034038 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CR30087, CG8215, SP41" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG30087 16-Dec-15 2015_12 WBGene00006621(try-3) viable FBgn0260466 Indy-2 I'm not dead yet 2 http://flybase.net/reports/FBgn0260466.html "FBgn0038770, FBgn0044655, FBgn0052921, FBgn0053933, FBtr0083832, FBpp0083241, FBtr0083833, FBpp0083242, FBtr0083834, FBpp0083243" protein_coding_gene "0015137=citrate transmembrane transporter activity, 0017153=sodium:dicarboxylate symporter activity, 0015141=succinate transmembrane transporter activity, 0050833=pyruvate transmembrane transporter activity" "0015746=citrate transport, 0008340=determination of adult lifespan, 0055085=transmembrane transport, 0006848=pyruvate transport, 0015744=succinate transport, 0006814=sodium ion transport, 0006810=transport" 0005887=integral component of plasma membrane "anon-WO0140519.217, CG33933, CG4961, CG32921" "IPR001898=Sodium/sulphate symporter, IPR031312=Sodium/sulphate symporter, conserved site" CG33933 16-Dec-15 2015_12 FBgn0069414 JJF164 JJF164 http://flybase.net/reports/FBgn0069414.html gene 16-Dec-15 2015_12 stress response defective FBgn0035786 Tsp66A Tetraspanin 66A http://flybase.net/reports/FBgn0035786.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp66A, CG1699, CG16991" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG16991 16-Dec-15 2015_12 FBgn0035148 CG3402 http://flybase.net/reports/FBgn0035148.html FBgn0047224 protein_coding_gene "0030111=regulation of Wnt signaling pathway, 0007266=Rho protein signal transduction" BcDNA:LD06317 "IPR001478=PDZ domain, IPR017268=Tax1-binding protein 3" CG3402 16-Dec-15 2015_12 ENSDARG00000059177(tax1bp3) WBGene00016678(C45G9.7) ENSXETG00000005800(TAX1BP3) ENSMUSG00000040158(Tax1bp3) ENSG00000213977(TAX1BP3) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0085460 CG34431 http://flybase.net/reports/FBgn0085460.html "FBgn0033237, FBan0014766" protein_coding_gene CG14766 CG34431 16-Dec-15 2015_12 FBgn0263941 BG00121 http://flybase.net/reports/FBgn0263941.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0028380 fal falten http://flybase.net/reports/FBgn0028380.html FBgn0036863 protein_coding_gene 0003924=GTPase activity 0007369=gastrulation "Q9VVY4_DROME, CG9670" "IPR006674=HD domain, IPR003607=HD/PDEase domain" CG9670 16-Dec-15 2015_12 "ENSDARG00000052054,ENSDARG00000052053,ENSDARG00000071288(si:dkeyp-44b8.8)" WBGene00022673(ZK177.8) ENSMUSG00000027639(Samhd1) viable DRSC11087 E -1.003268317 -0.02813143 1.685470732 1.182592967 -1.064316741 -0.319328393 FBgn0267337 rn rotund http://flybase.net/reports/FBgn0267337.html "FBgn0259172, FBgn0003263, FBgn0003269, FBgn0037494, FBgn0037495, FBgn0037496, FBgn0037497, FBgn0052466, FBgn0052467, FBgn0260876, FBgn0260875" protein_coding_gene "0046872=metal ion binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" "0001708=cell fate specification, 0022416=chaeta development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development, 0007480=imaginal disc-derived leg morphogenesis, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "t-one transformed, roe, CG14600, CG10040, roughened eye, Rotund, CG42277, CG32467, Distal-into-proximal, CG32466, P5.3, CG14601, Dipr, 5.3, Rn, tot, CG14603, tod, T-one deficient" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG42277 16-Dec-15 2015_12 YJL056C(ZAP1) "ENSMUSG00000038346(Zfp384),ENSMUSG00000028799(Zfp362)" ENSG00000126746(ZNF384) " spermatogenesis && adult stage , prepupal stage | 0-2 hr , pupal stage | early , pupal stage && spermatogenesis && adult stage , embryonic stage--pupal stage , larval stage && pupal stage " " testis

, dorsal metathoracic disc

, imaginal disc

, adepithelial cell &&of dorsal mesothoracic disc

, ventral thoracic disc

, genital disc

, labial disc

, antennal disc

, spermatocyte

, dorsal mesothoracic disc

" """DRSC12543, DRSC22291"" " EK FBgn0027623 297\env env http://flybase.net/reports/FBgn0027623.html transposable_element_gene env "IPR012014=Retroelement-encoded protein, env-related" 16-Dec-15 2015_12 FBgn0014373 poil-rare poil-rare http://flybase.net/reports/FBgn0014373.html gene 16-Dec-15 2015_12 FBgn0263246 CG43389 http://flybase.net/reports/FBgn0263246.html protein_coding_gene CG43389 16-Dec-15 2015_12 FBgn0005659 Ets98B Ets at 98B http://flybase.net/reports/FBgn0005659.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0008354=germ cell migration" 0005634=nucleus "ets98B, CG5583, Ets4, ETS4, Ets, D-ets4, D-Ets-4, D-ets-4" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain, IPR013761=Sterile alpha motif/pointed domain, IPR003118=Pointed domain" CG5583 16-Dec-15 2015_12 ENSDARG00000029930(LOC100003543) WBGene00017687(ets-4) ENSMUSG00000024215(Spdef) ENSG00000124664(SPDEF) embryonic stage "

ubiquitous , pole cell

" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086602 snoRNA:ë¬28S-3436b snoRNA:ë¬28S-3436b http://flybase.net/reports/FBgn0086602.html "FBgn0053799, FBgn0065052, FBgn0082955" snoRNA_gene 0005730=nucleolus "CR33799, Psi28S-3436b, psi28S-3436b, snoR75, Dm-75, snoRNA:75" CR33799 16-Dec-15 2015_12 FBgn0003951 uncl uncoordinated-like http://flybase.net/reports/FBgn0003951.html gene "0007605=sensory perception of sound, 0008344=adult locomotory behavior, 0048477=oogenesis" "R-10-10, l(1)R10-10, uncoordinatedlike, l(1)Q-456, l(1)20Ae, section 25, section 24, Q456, l(1)R-10-10, 25, 17, 24, section 17" 16-Dec-15 2015_12 "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective,lethal,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,touch sensitivity defective,germline clone,maternal effect,lethal - all die before end of larval stage,some die during larval stage,touch perception defective,somatic clone" "wing,leg,macrochaeta,adult antennal nerve,egg chamber,germline clone,maternal effect" FBgn0003667 tiny-bristle tiny bristle http://flybase.net/reports/FBgn0003667.html gene tb 16-Dec-15 2015_12 female semi-sterile "macrochaeta,wing" FBgn0084775 EP2370 EP2370 http://flybase.net/reports/FBgn0084775.html gene 16-Dec-15 2015_12 FBgn0032079 CG31886 http://flybase.net/reports/FBgn0032079.html "FBgn0046439, FBgn0046441, FBgn0051886" protein_coding_gene "CG9524, anon-WO0172774.161, anon-WO0172774.159" CG31886 16-Dec-15 2015_12 "chemical sensitive,viable" FBgn0005317 N-b Notch b http://flybase.net/reports/FBgn0005317.html gene "N-2, Notch 2" 16-Dec-15 2015_12 "visible,dominant" wing FBgn0037315 Cerk Ceramide kinase http://flybase.net/reports/FBgn0037315.html protein_coding_gene "0001729=ceramide kinase activity, 0017050=D-erythro-sphingosine kinase activity" "0007476=imaginal disc-derived wing morphogenesis, 0007602=phototransduction, 0006672=ceramide metabolic process, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0007280=pole cell migration" 0005886=plasma membrane "Dcerk, CG16708, DCERK, CerK, ceramide kinase, dcerk" "IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR001206=Diacylglycerol kinase, catalytic domain" CG16708 16-Dec-15 2015_12 "ENSDARG00000037267(zgc:158263),ENSDARG00000069169(cerk)" WBGene00020398(T10B11.2) ENSXETG00000023320(CERK) ENSMUSG00000035891(Cerk) ENSG00000100422(CERK) "partially lethal - majority die,neurophysiology defective,viable,visible,some die during pupal stage" "rhabdomere,eye photoreceptor cell,trichogen cell,mesothoracic tergum" FBgn0260721 CR42548 http://flybase.net/reports/FBgn0260721.html pseudogene_attribute CR42548 16-Dec-15 2015_12 FBgn0027123 l(?)13R lethal (?) 13R http://flybase.net/reports/FBgn0027123.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0004428 LysE Lysozyme E http://flybase.net/reports/FBgn0004428.html "FBgn0002575, FBgn0063103" protein_coding_gene 0003796=lysozyme activity "0050829=defense response to Gram-negative bacterium, 0045824=negative regulation of innate immune response, 0019730=antimicrobial humoral response" "CG1180, BcDNA:LP07339, lysE, Lys E" "IPR019799=Glycoside hydrolase, family 22, conserved site, IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain" CG1180 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) " larval stage&&adult stage , adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0039180 CG5715 http://flybase.net/reports/FBgn0039180.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0006508=proteolysis, 0006909=phagocytosis" 0017090=meprin A complex "IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR001506=Peptidase M12A, astacin" CG5715 16-Dec-15 2015_12 "ENSDARG00000019122(he1b),ENSDARG00000023656(he1a),ENSDARG00000022670(he2),ENSDARG00000058409,ENSDARG00000010423(npsn),ENSDARG00000024503(c6ast3),ENSDARG00000052578(c6ast4),ENSDARG00000070011(LOC100003133),ENSDARG00000069216(c6ast1)" "WBGene00003523(nas-4),WBGene00003532(nas-13)" ENSXETG00000015923() ENSMUSG00000050468(Astl) ENSG00000188886(ASTL) viable FBgn0000049 l(1)adl1 lethal (1) adl1 http://flybase.net/reports/FBgn0000049.html FBgn0005127 gene "addA, adult lethal A, adl-1, l(1)J1649, l(1)adl-1, l(1)7Dn" 16-Dec-15 2015_12 "behavior defective,heat sensitive,lethal" FBgn0086380 BG00386 http://flybase.net/reports/FBgn0086380.html gene "0002121=inter-male aggressive behavior, 0042048=olfactory behavior" 16-Dec-15 2015_12 "viable,smell perception defective,behavior defective,recessive" FBgn0010029 E(Dl)F42 Enhancer of Delta F42 http://flybase.net/reports/FBgn0010029.html gene 16-Dec-15 2015_12 FBgn0069108 mus316 mutagen-sensitive 316 http://flybase.net/reports/FBgn0069108.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0262442 mir-2501 mir-2501 stem loop http://flybase.net/reports/FBgn0262442.html "FBgn0262137, FBgn0262298" miRNA_gene CR43005 CR43005 16-Dec-15 2015_12 viable FBgn0010547 l(2)03605 lethal (2) 03605 http://flybase.net/reports/FBgn0010547.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053107 CG33107 http://flybase.net/reports/FBgn0053107.html protein_coding_gene CG5275 CG33107 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC21898 K -0.259922383 0.837030916 -0.238442443 0.456770809 2.008709802 -0.938442979 FBgn0052198 CG32198 http://flybase.net/reports/FBgn0052198.html protein_coding_gene CG32198 16-Dec-15 2015_12 viable FBgn0053310 CG33310 http://flybase.net/reports/FBgn0053310.html "FBgn0028924, FBgn0032558" protein_coding_gene 0005391=sodium:potassium-exchanging ATPase activity "0006813=potassium ion transport, 0006814=sodium ion transport" "0016020=membrane, 0005890=sodium:potassium-exchanging ATPase complex" "BG:DS00929.6, CG15274" IPR000402=Sodium/potassium-transporting ATPase subunit beta CG33310 16-Dec-15 2015_12 viable FBgn0033860 S-Lap5 Sperm-Leucylaminopeptidase 5 http://flybase.net/reports/FBgn0033860.html protein_coding_gene "0008235=metalloexopeptidase activity, 0030145=manganese ion binding, 0004177=aminopeptidase activity" "0006508=proteolysis, 0007498=mesoderm development" 0005737=cytoplasm "CG18369, S-LAP 5, Sperm-LeucylAminoPeptidase 5" "IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal" CG18369 16-Dec-15 2015_12 FBgn0035039 Adck aarF domain containing kinase http://flybase.net/reports/FBgn0035039.html protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding" "0090277=positive regulation of peptide hormone secretion, 0006468=protein phosphorylation, 0040018=positive regulation of multicellular organism growth" "cg3608, CG3608" "IPR000719=Protein kinase domain, IPR004147=UbiB domain, IPR011009=Protein kinase-like domain" CG3608 16-Dec-15 2015_12 ENSDARG00000062561(adck1) YLR253W() WBGene00008410(D2023.6) ENSXETG00000011088(Q5M7P6_XENTR) ENSMUSG00000021044(Adck1) ENSG00000063761(ADCK1) "viable,visible" trichogen cell FBgn0005185 l(2)S13 lethal of Seto 13 http://flybase.net/reports/FBgn0005185.html gene 16-Dec-15 2015_12 lethal FBgn0262283 mir-985 mir-985 stem loop http://flybase.net/reports/FBgn0262283.html miRNA_gene "CR42990, dme-mir-985, lincRNA.1008, miR-985" CR42990 16-Dec-15 2015_12 viable FBgn0010530 l(2)03105 lethal (2) 03105 http://flybase.net/reports/FBgn0010530.html FBgn0021809 gene "l(2)3105, l(2)k16702" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267063 CR45507 http://flybase.net/reports/FBgn0267063.html non_protein_coding_gene CR45507 16-Dec-15 2015_12 FBgn0262578 CG43118 http://flybase.net/reports/FBgn0262578.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267492 Mst77Y-7 Male-specific transcript 77Y 7 http://flybase.net/reports/FBgn0267492.html "FBgn0262756, FBgn0267415" protein_coding_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin CG45768 CG45768 16-Dec-15 2015_12 FBgn0051199 CG31199 http://flybase.net/reports/FBgn0051199.html FBgn0038823 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis CG17837 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG31199 16-Dec-15 2015_12 viable FBgn0000586 es ether-sensitive http://flybase.net/reports/FBgn0000586.html gene 16-Dec-15 2015_12 "viable,reduced,chemical sensitive,recessive" FBgn0005710 l(1)TK113 lethal (1) TK113 http://flybase.net/reports/FBgn0005710.html gene l113 16-Dec-15 2015_12 "lethal,recessive" eye FBgn0016958 tilO touch insensitive larva O http://flybase.net/reports/FBgn0016958.html gene line 317 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective,visible,somatic clone" "macrochaeta,somatic clone,trichome" FBgn0067089 I16 I16 http://flybase.net/reports/FBgn0067089.html gene 16-Dec-15 2015_12 lethal FBgn0027652 l(2)32BCa lethal (2) 32BCa http://flybase.net/reports/FBgn0027652.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0004172 Mst84Da Male-specific RNA 84Da http://flybase.net/reports/FBgn0004172.html protein_coding_gene "0007288=sperm axoneme assembly, 0007283=spermatogenesis" "mst(3)gl-1, Mst ORF, Mstprox, Mst, Mst87D, CG17946, Mst84" IPR005634=Male specific sperm protein CG17946 16-Dec-15 2015_12 FBgn0038953 CG18596 http://flybase.net/reports/FBgn0038953.html protein_coding_gene "0008173=RNA methyltransferase activity, 0003723=RNA binding" 0006396=RNA processing "IPR029026=tRNA (guanine-N1-)-methyltransferase, N-terminal, IPR029028=Alpha/beta knot methyltransferases, IPR001537=tRNA/rRNA methyltransferase, SpoU type" CG18596 16-Dec-15 2015_12 YDL112W(TRM3) ENSXETG00000016224(TARBP1) ENSG00000059588(TARBP1) viable FBgn0011246 ms(2)42D male sterile (2) 42D http://flybase.net/reports/FBgn0011246.html gene "unnamed, ms(2)09967" 16-Dec-15 2015_12 male semi-sterile FBgn0030630 CG12608 http://flybase.net/reports/FBgn0030630.html protein_coding_gene 0005515=protein binding 0008283=cell proliferation 0005730=nucleolus "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG12608 16-Dec-15 2015_12 ENSDARG00000044488(zgc:56683) YKL021C(MAK11) ENSXETG00000001072(PAK1IP1) ENSMUSG00000038683(Pak1ip1) ENSG00000111845(PAK1IP1) FBgn0031800 CG9497 http://flybase.net/reports/FBgn0031800.html protein_coding_gene "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG9497 16-Dec-15 2015_12 "WBGene00007810(C29F7.1),WBGene00007811(C29F7.2),WBGene00014192(nhr-246)" "viable,fertile" FBgn0083961 CG34125 http://flybase.net/reports/FBgn0083961.html "FBan0031652, FBgn0051652" protein_coding_gene CG31652 IPR022730=DAZ associated protein 2 CG34125 16-Dec-15 2015_12 FBgn0023183 Ocu Oculess http://flybase.net/reports/FBgn0023183.html gene 16-Dec-15 2015_12 FBgn0086030 snoRNA:Me18S-G393 http://flybase.net/reports/FBgn0086030.html snoRNA_gene "CR34659, Me18S-Gm393" CR34659 16-Dec-15 2015_12 FBgn0016048 noose noose http://flybase.net/reports/FBgn0016048.html gene 16-Dec-15 2015_12 "lethal,recessive" embryonic/larval brain FBgn0028054 l(3)S095109 lethal (3) S095109 http://flybase.net/reports/FBgn0028054.html gene 0951/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0066371 beluy beluy http://flybase.net/reports/FBgn0066371.html gene "0008355=olfactory learning, 0007611=learning or memory" Beluy 16-Dec-15 2015_12 "learning defective,memory defective" FBgn0015407 l(1)12Bb lethal (1) 12Bb http://flybase.net/reports/FBgn0015407.html gene 16-Dec-15 2015_12 "partially lethal - majority die,visible,male fertile,body color defective" "wing,adult abdomen,female" FBgn0036360 CG10713 http://flybase.net/reports/FBgn0036360.html protein_coding_gene CT28585 CG10713 16-Dec-15 2015_12 viable FBgn0002971 Nuc Nuclease http://flybase.net/reports/FBgn0002971.html gene 0004536=deoxyribonuclease activity 16-Dec-15 2015_12 FBgn0005055 fs(2)OW101 female sterile (2) OW101 http://flybase.net/reports/FBgn0005055.html gene 16-Dec-15 2015_12 FBgn0265893 CR44682 http://flybase.net/reports/FBgn0265893.html non_protein_coding_gene CR44682 16-Dec-15 2015_12 FBgn0051064 CG31064 http://flybase.net/reports/FBgn0051064.html "FBgn0039496, FBgn0039497" protein_coding_gene 0046872=metal ion binding 0006909=phagocytosis "CG6001, CG14261" "IPR000306=FYVE zinc finger, IPR004012=RUN domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG31064 16-Dec-15 2015_12 "ENSDARG00000029692(rufy3),ENSDARG00000062019(rufy2)" ENSXETG00000023647(RUFY3) "ENSG00000018189(RUFY3),ENSG00000204130(RUFY2),ENSG00000176783(RUFY1)" viable FBgn0263974 qin qin http://flybase.net/reports/FBgn0263974.html "FBgn0038633, FBgn0038628" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0035194=posttranscriptional gene silencing by RNA, 0051865=protein autoubiquitination" "0043186=P granule, 0005634=nucleus" "CG43726, kumo, CG14306, CG14303" "IPR002999=Tudor domain, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000315=B-box-type zinc finger, IPR017907=Zinc finger, RING-type, conserved site" CG43726 16-Dec-15 2015_12 FBgn0044068 F72 F72 http://flybase.net/reports/FBgn0044068.html gene 16-Dec-15 2015_12 FBgn0001015 fs(3)A6 female sterile (3) A6 http://flybase.net/reports/FBgn0001015.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0051286 CG31286 http://flybase.net/reports/FBgn0051286.html "FBgn0045981, FBgn0063709" protein_coding_gene 0005576=extracellular region "BcDNA:AT25568, NEST:bs36b12" "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG31286 16-Dec-15 2015_12 FBgn0028342 ATPsynë« "ATP synthase, ë« subunit" http://flybase.net/reports/FBgn0028342.html "FBgn0030184, FBgn0066857, FBgn0066858" protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism, 0046961=proton-transporting ATPase activity, rotational mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism" "0015992=proton transport, 0015986=ATP synthesis coupled proton transport" "0005811=lipid particle, 0005739=mitochondrion, 0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)" "ATP synthase Delta chain, F0/F1 ATP synthase Delta, l(1)G0230, ATP synthase delta chain, CG2968, ATP5D, l (1) G0230, anon-WO03040301.109, anon-WO03040301.110, ATPD, lethal (1) G0230" "IPR020546=ATPase, F1 complex, delta/epsilon subunit, N-terminal, IPR020547=ATP synthase delta/epsilon subunit, C-terminal domain, IPR001469=ATPase, F1 complex, delta/epsilon subunit" CG2968 16-Dec-15 2015_12 ENSDARG00000019404(atp5d) YDL004W(ATP16) WBGene00019061(F58F12.1) ENSXETG00000003283(ATP5D) ENSMUSG00000003072(Atp5d) ENSG00000099624(ATP5D) "viable,fertile,lethal,recessive" FBgn0266962 CG45413 http://flybase.net/reports/FBgn0266962.html protein_coding_gene CG45413 16-Dec-15 2015_12 FBgn0086402 BG02510 http://flybase.net/reports/FBgn0086402.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0011966 tRNA:R:85Ca transfer RNA:arg:85Ca http://flybase.net/reports/FBgn0011966.html "FBgn0003756, FBgn0011947, FBgn0051443, FBgn0060076" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033431=CGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:arg85Ca, AE002708.trna1-ArgTCG, tRNA-Arg, tRNA:R:TCG:AE002708-a, tRNA[arg], transfer RNA:arg1, tRNA:R1, tRNA:arg1, CR31443, chr3R.trna7-ArgTCG" CR31443 16-Dec-15 2015_12 FBgn0001394 l(1)2Da lethal (1) 2Da http://flybase.net/reports/FBgn0001394.html gene l(1)DF967 16-Dec-15 2015_12 "partially lethal - majority die,cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0044478 EP643 EP643 http://flybase.net/reports/FBgn0044478.html gene "EP0643, unnamed" 16-Dec-15 2015_12 intersegmental nerve FBgn0005380 l(3)SG76 lethal (3) SG76 http://flybase.net/reports/FBgn0005380.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0038716 CG7342 http://flybase.net/reports/FBgn0038716.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG7342 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0085724 CG41622 http://flybase.net/reports/FBgn0085724.html FBan0041622 protein_coding_gene 16-Dec-15 2015_12 FBgn0039752 CG15530 http://flybase.net/reports/FBgn0039752.html protein_coding_gene CG15530 16-Dec-15 2015_12 viable FBgn0070052 2L-393-17 2L-393-17 http://flybase.net/reports/FBgn0070052.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "dorsal closure embryo,germline clone,maternal effect" FBgn0082360 HM160 HM160 http://flybase.net/reports/FBgn0082360.html gene 16-Dec-15 2015_12 FBgn0060618 l(3)S089013 lethal (3) S089013 http://flybase.net/reports/FBgn0060618.html gene 0890/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060933 l(3)S041506 lethal (3) S041506 http://flybase.net/reports/FBgn0060933.html gene 0415/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0002570 Mal-A1 Maltase A1 http://flybase.net/reports/FBgn0002570.html protein_coding_gene "0003824=catalytic activity, 0004558=alpha-1,4-glucosidase activity, 0043169=cation binding" "0006006=glucose metabolic process, 0005975=carbohydrate metabolic process" "H, Larval visceral protein H, maltase, V, hdl cuticle gene cluster, gene V, mal_A1, lvpH, CG8696, Drome_A1, maltase H precursor, LvpH" "IPR013781=Glycoside hydrolase, catalytic domain, IPR015902=Glycoside hydrolase, family 13, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain" CG8696 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) " larval stage | early third instar larval stage , larval stage | first instar , adult stage , larval stage | second instar " organism

viable FBgn0014305 l(3)neo53a lethal (3) neo53a http://flybase.net/reports/FBgn0014305.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011788 l(3)j1B8 lethal (3) j1B8 http://flybase.net/reports/FBgn0011788.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062686 EP1501 EP1501 http://flybase.net/reports/FBgn0062686.html gene EP(X)1501 16-Dec-15 2015_12 wild-type FBgn0029750 CG3323 http://flybase.net/reports/FBgn0029750.html protein_coding_gene CG3323 16-Dec-15 2015_12 FBgn0085830 CR42197 http://flybase.net/reports/FBgn0085830.html FBan0042197 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0266926 CR45377 http://flybase.net/reports/FBgn0266926.html non_protein_coding_gene CR45377 16-Dec-15 2015_12 FBgn0002948 nod no distributive disjunction http://flybase.net/reports/FBgn0002948.html protein_coding_gene "0051010=microtubule plus-end binding, 0003677=DNA binding, 0003777=microtubule motor activity, 0005524=ATP binding" "0051296=establishment of meiotic spindle orientation, 0045132=meiotic chromosome segregation, 0006281=DNA repair, 0031116=positive regulation of microtubule polymerization, 0007143=female meiotic division, 0007057=spindle assembly involved in female meiosis I, 0007018=microtubule-based movement, 0032837=distributive segregation, 0007052=mitotic spindle organization" 0005871=kinesin complex "DnMod, DmNod, No distributive disjunction, kinesin-10, kineskin-10, No Distributive Disjunction, Nod, KIF22, NOD, l(1)TW6, KIF 22, CG1763" "IPR003583=Helix-hairpin-helix DNA-binding motif, class 1, IPR027640=Kinesin-like protein, IPR010994=RuvA domain 2-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain" CG1763 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-3 , embryonic stage -- adult stage " " germarium

, ovariole

" "viable,meiotic cell cycle defective,female,fertile,recessive,lethal,male,cold sensitive,mitotic cell cycle defective,dominant" "meiosis & nuclear chromosome | female,meiosis & nuclear chromosome & oocyte,mitosis & nuclear chromosome,polytene chromosome chromocenter" FBgn0265748 CR44555 http://flybase.net/reports/FBgn0265748.html non_protein_coding_gene lincRNA.542 CR44555 16-Dec-15 2015_12 FBgn0019887 anon-50Aa anon-50Aa http://flybase.net/reports/FBgn0019887.html gene unnamed 16-Dec-15 2015_12 visible eye FBgn0265525 CR44375 http://flybase.net/reports/FBgn0265525.html non_protein_coding_gene CR44375 16-Dec-15 2015_12 FBgn0069085 sax::wit sax::wit http://flybase.net/reports/FBgn0069085.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0067770 frk franklin http://flybase.net/reports/FBgn0067770.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 lethal "egg chamber,germline clone" FBgn0014136 cact::N cact::N http://flybase.net/reports/FBgn0014136.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0031138 CG11229 http://flybase.net/reports/FBgn0031138.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0082341 HM54 HM54 http://flybase.net/reports/FBgn0082341.html gene 16-Dec-15 2015_12 FBgn0026063 KP78b KP78b http://flybase.net/reports/FBgn0026063.html FBgn0022392 protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "Kp78b, CG17216, KP78B, Kp78B" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG17216 16-Dec-15 2015_12 "YLR096W(KIN2),YDR122W(KIN1)" embryonic stage | extended germ band mesoderm | segmentally repeated

FBgn0266889 CR45350 http://flybase.net/reports/FBgn0266889.html non_protein_coding_gene CR45350 16-Dec-15 2015_12 FBgn0028187 l(3)S023825 lethal (3) S023825 http://flybase.net/reports/FBgn0028187.html "FBgn0060460, FBgn0060660, FBgn0060663, FBgn0060689, FBgn0060718, FBgn0060722, FBgn0060770, FBgn0060911, FBgn0060969, FBgn0060973, FBgn0061039, FBgn0061040" gene "l(3)S042824, l(3)S068502, 0685/02, 1165/12, l(3)S116512, 0621/12, 0610/02, l(3)S023826, l(3)S069007, l(3)S062112, 0826/09, 0428/24, l(3)S074309a, 0238/16, 0300/04, 0238/25, l(3)S023816, 0816/07, 0291/20, 0238/26, 0690/07, l(3)S030004, l(3)S029120, 0238/20, l(3)S081607, l(3)S082609a, 0743/09" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0031409 CG4271 http://flybase.net/reports/FBgn0031409.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH164 "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG4271 16-Dec-15 2015_12 viable FBgn0020271 moa moa http://flybase.net/reports/FBgn0020271.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces "sac, l(2)59ABd" 16-Dec-15 2015_12 "lethal,recessive,visible,somatic clone,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone,larva" FBgn0019876 e(olfC) e(olfC) http://flybase.net/reports/FBgn0019876.html gene "1a, anon-7Aa" 16-Dec-15 2015_12 FBgn0038225 soti scotti http://flybase.net/reports/FBgn0038225.html protein_coding_gene "0046331=lateral inhibition, 0007291=sperm individualization" "scotti, CG8489, soti" CG8489 16-Dec-15 2015_12 "viable,female fertile,male sterile,recessive,visible,body color defective" "individualization stage spermatid,chaeta,supernumerary,tormogen cell,mesothoracic tergum,waste bag,cystic bulge,nucleus & individualization stage spermatid" FBgn0259310 EP-Ib http://flybase.net/reports/FBgn0259310.html gene 16-Dec-15 2015_12 visible "wing,wing margin" FBgn0264790 CR44020 http://flybase.net/reports/FBgn0264790.html non_protein_coding_gene CR44020 16-Dec-15 2015_12 FBgn0011506 l(3)rK145 lethal (3) rK145 http://flybase.net/reports/FBgn0011506.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0065660 l(2)SH0714 lethal (2) SH0714 http://flybase.net/reports/FBgn0065660.html gene l(2)SH2 0714 16-Dec-15 2015_12 "lethal,recessive" FBgn0267186 CR45626 http://flybase.net/reports/FBgn0267186.html non_protein_coding_gene CR45626 16-Dec-15 2015_12 FBgn0030297 Gr10b Gustatory receptor 10b http://flybase.net/reports/FBgn0030297.html protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG12622, Gustatory receptor 10B2, GR10b, Gr10B2" IPR013604=7TM chemoreceptor CG12622 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0046323 ORY Occludin-Related Y http://flybase.net/reports/FBgn0046323.html "FBgn0058446, FBan0040446" protein_coding_gene "Occludin-related Y, ory, CG40446, ORY, Ory" CG40446 16-Dec-15 2015_12 FBgn0034537 DMAP1 DNA methyltransferase 1 associated protein 1 http://flybase.net/reports/FBgn0034537.html protein_coding_gene "0006909=phagocytosis, 0045089=positive regulation of innate immune response, 0016573=histone acetylation, 0043968=histone H2A acetylation, 0002225=positive regulation of antimicrobial peptide production, 0006338=chromatin remodeling, 0045892=negative regulation of transcription, DNA-templated, 0006281=DNA repair, 0043967=histone H4 acetylation" "0005634=nucleus, 0035267=NuA4 histone acetyltransferase complex" "DMAP1, CG11132, DMA, Q7K3D8_DROME, dDMAP1" "IPR008468=DNA methyltransferase 1-associated 1, IPR001005=SANT/Myb domain, IPR027109=SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1" CG11132 16-Dec-15 2015_12 ENSDARG00000042087(dmap1) YGR002C(SWC4) WBGene00013676(ekl-4) ENSXETG00000001057(dmap1) ENSMUSG00000009640(Dmap1) ENSG00000178028(DMAP1) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" DRSC06044 IEK -0.472910919 -1.852406259 0.852557476 -4.447652564 1.572572328 0.947616583 FBgn0039326 CG10562 http://flybase.net/reports/FBgn0039326.html protein_coding_gene "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG10562 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" "viable,visible" mesothoracic tergum FBgn0001842 l(1)ts1704 lethal (1) ts1704 http://flybase.net/reports/FBgn0001842.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0022105 l(2)k07109a lethal (2) k07109a http://flybase.net/reports/FBgn0022105.html gene l(2)k07109 16-Dec-15 2015_12 "lethal,recessive" FBgn0016715 Reg-2 Rhythmically expressed gene 2 http://flybase.net/reports/FBgn0016715.html protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process "Drosophila Rhythmically expressed gene 2, rhythmically expressed gene 2, Dreg-2, 21483246, CG3200" "IPR023214=HAD-like domain, IPR006439=HAD hydrolase, subfamily IA, IPR011949=HAD-superfamily hydrolase, subfamily IA, REG-2-like" CG3200 16-Dec-15 2015_12 ENSDARG00000053934(si:ch211-10e8.6) YMR130W() WBGene00010481(K01G5.10) ENSMUSG00000038422(Hdhd3) adult stage viable FBgn0036057 CG14164 http://flybase.net/reports/FBgn0036057.html protein_coding_gene IPR019181=Anticodon-binding domain CG14164 16-Dec-15 2015_12 YHR121W(LSM12) ENSXETG00000003371(LSM12) FBgn0267597 CR45935 http://flybase.net/reports/FBgn0267597.html non_protein_coding_gene lincRNA.600 CR45935 16-Dec-15 2015_12 FBgn0266251 CR44946 http://flybase.net/reports/FBgn0266251.html non_protein_coding_gene lincRNA.805 CR44946 16-Dec-15 2015_12 FBgn0000975 fs(2)HO100 female sterile (2) HO100 http://flybase.net/reports/FBgn0000975.html gene fs(2)100A 16-Dec-15 2015_12 "female sterile,recessive" ovary FBgn0038469 CG4009 http://flybase.net/reports/FBgn0038469.html protein_coding_gene "0020037=heme binding, 0004601=peroxidase activity" "0055114=oxidation-reduction process, 0006979=response to oxidative stress" 0042600=chorion "IPR019791=Haem peroxidase, animal, IPR010255=Haem peroxidase, IPR029585=Peroxidase, insect" CG4009 16-Dec-15 2015_12 "WBGene00022743(mlt-7),WBGene00017968(F32A5.2)" viable FBgn0013339 Spf Spadefoot http://flybase.net/reports/FBgn0013339.html gene 16-Dec-15 2015_12 "visible,dominant" FBgn0053511 CG33511 http://flybase.net/reports/FBgn0053511.html FBgn0032912 protein_coding_gene CG14398 "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG33511 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" FBgn0058236 CG40236 http://flybase.net/reports/FBgn0058236.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262065 SG16 http://flybase.net/reports/FBgn0262065.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031659 CG14043 http://flybase.net/reports/FBgn0031659.html protein_coding_gene 0006839=mitochondrial transport 0005739=mitochondrion "IPR022083=KIF-1 binding protein, IPR011990=Tetratricopeptide-like helical domain" CG14043 16-Dec-15 2015_12 ENSDARG00000062053(kbp) ENSXETG00000008834(KIAA1279) ENSMUSG00000036955(2510003E04Rik) ENSG00000198954(KIAA1279) viable FBgn0000517 dw-24E dwarf 24F http://flybase.net/reports/FBgn0000517.html gene dw-24F 16-Dec-15 2015_12 "visible,viable,reduced,fertile" "adult abdomen,adult thorax,eye,wing,macrochaeta" FBgn0267516 pre-rRNA-ë¬:CR45856 ribosomal RNA primary transcript pseudogene:CR45856 http://flybase.net/reports/FBgn0267516.html pseudogene_attribute CR45856 CR45856 16-Dec-15 2015_12 FBgn0051055 CG31055 http://flybase.net/reports/FBgn0051055.html "FBgn0046009, FBgn0046104, FBgn0063715, FBgn0065017" protein_coding_gene "BcDNA:AT11054, NEST:bs01f03, NEST:bs23c05, bs23c05.y1, BcDNA:AT22836" CG31055 16-Dec-15 2015_12 viable FBgn0031219 CG13694 http://flybase.net/reports/FBgn0031219.html protein_coding_gene IPR002350=Kazal domain CG13694 16-Dec-15 2015_12 viable FBgn0053202 dpr11 defective proboscis extension response 11 http://flybase.net/reports/FBgn0053202.html "FBgn0037450, FBgn0037451, FBgn0037452, FBgn0051309, FBgn0063228" protein_coding_gene 0007606=sensory perception of chemical stimulus "BcDNA:GH22307, dpr11, CG33202, CG31309, Dpr-11, CG15181, CT35098, Dpr11, CG15182, CG15183" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR013151=Immunoglobulin" CG33202 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) "viable,fertile" FBgn0046225 CG17230 http://flybase.net/reports/FBgn0046225.html "FBgn0037903, FBgn0037907" protein_coding_gene "CG5286, BcDNA:GH24095" CG17230 16-Dec-15 2015_12 viable FBgn0036830 CG14077 http://flybase.net/reports/FBgn0036830.html protein_coding_gene 0004129=cytochrome-c oxidase activity 0005751=mitochondrial respiratory chain complex IV VIa "IPR001349=Cytochrome c oxidase, subunit VIa" CG14077 16-Dec-15 2015_12 viable DRSC10082 K -0.669673064 0.96390079 -0.368771524 0.802115012 1.724375166 -0.645718191 FBgn0060333 l(3)S145609 lethal (3) S145609 http://flybase.net/reports/FBgn0060333.html gene 1456/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0067097 H71 H71 http://flybase.net/reports/FBgn0067097.html gene 16-Dec-15 2015_12 "lethal,viable" FBgn0065275 l(2)SH2049 lethal (2) SH2049 http://flybase.net/reports/FBgn0065275.html gene l(2)SH2 2049 16-Dec-15 2015_12 "lethal,recessive" FBgn0082947 snoRNA:Me18S-U1356c snoRNA:Me18S-U1356c http://flybase.net/reports/FBgn0082947.html snoRNA_gene "Me18S-Um1356c, CR34646" CR34646 16-Dec-15 2015_12 FBgn0266095 CR44832 http://flybase.net/reports/FBgn0266095.html non_protein_coding_gene CR44832 16-Dec-15 2015_12 FBgn0051109 CG31109 http://flybase.net/reports/FBgn0051109.html "FBgn0039267, FBgn0047157" protein_coding_gene 0008270=zinc ion binding 0005634=nucleus "BcDNA:RE17222, CG13649" "IPR012934=Zinc finger, AD-type" CG31109 16-Dec-15 2015_12 "viable,fertile" FBgn0265103 CR44205 http://flybase.net/reports/FBgn0265103.html non_protein_coding_gene CG44205 CR44205 16-Dec-15 2015_12 FBgn0030925 Hayan Hayan http://flybase.net/reports/FBgn0030925.html protein_coding_gene 0004252=serine-type endopeptidase activity "0035007=regulation of melanization defense response, 0006508=proteolysis" "Hayan, c-SP31, CG6361, SP31" "IPR006604=Disulphide knot CLIP, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG6361 16-Dec-15 2015_12 "short lived,conditional,viable,fertile,wound healing defective,partially lethal - majority die,some die during larval stage" trachea FBgn0027305 l(1)G0120 lethal (1) G0120 http://flybase.net/reports/FBgn0027305.html gene l(1)G01290 16-Dec-15 2015_12 "lethal,recessive" FBgn0065980 iab-6-1.as iab-6-1.as http://flybase.net/reports/FBgn0065980.html gene 6-1 as 16-Dec-15 2015_12 FBgn0034096 CG7786 http://flybase.net/reports/FBgn0034096.html protein_coding_gene "0042803=protein homodimerization activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0006351=transcription, DNA-templated" 0005634=nucleus "DM33, DM7" IPR004827=Basic-leucine zipper domain CG7786 16-Dec-15 2015_12 ENSXETG00000006333(TEF) viable FBgn0032490 CG16813 http://flybase.net/reports/FBgn0032490.html protein_coding_gene 0046983=protein dimerization activity DM26 CG16813 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032733 CG15170 http://flybase.net/reports/FBgn0032733.html protein_coding_gene 0042060=wound healing IPR008472=Domain of unknown function DUF753 CG15170 16-Dec-15 2015_12 viable FBgn0265819 CR44608 http://flybase.net/reports/FBgn0265819.html non_protein_coding_gene lincRNA.31 CR44608 16-Dec-15 2015_12 FBgn0000918 fs(1)ne4 female sterile (1) no eggs 4 http://flybase.net/reports/FBgn0000918.html gene "fs(1)ne[4], ne4" 16-Dec-15 2015_12 "female sterile,recessive,female sterile germline-dependent" "dorsal appendage,chorion,endochorion,oocyte" FBgn0003493 spw spur wing http://flybase.net/reports/FBgn0003493.html gene 16-Dec-15 2015_12 "wing,wing vein" FBgn0038028 CG10035 http://flybase.net/reports/FBgn0038028.html FBgn0025945 protein_coding_gene "anon-EST:Liang-20, clone 20" CG10035 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0017383 l(1)1Ai lethal (1) 1Ai http://flybase.net/reports/FBgn0017383.html gene HM17 16-Dec-15 2015_12 "lethal,recessive" FBgn0025774 l(2)k04206 lethal (2) k04206 http://flybase.net/reports/FBgn0025774.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263566 mir-4909 mir-4909 stem loop http://flybase.net/reports/FBgn0263566.html miRNA_gene "dme-mir-4909, CR43551" CR43551 16-Dec-15 2015_12 FBgn0061042 l(3)S023733 lethal (3) S023733 http://flybase.net/reports/FBgn0061042.html gene 0237/33 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266897 CR45357 http://flybase.net/reports/FBgn0266897.html non_protein_coding_gene CR45357 16-Dec-15 2015_12 FBgn0266372 CR45016 http://flybase.net/reports/FBgn0266372.html non_protein_coding_gene CR45016 16-Dec-15 2015_12 FBgn0266312 CR44977 http://flybase.net/reports/FBgn0266312.html non_protein_coding_gene CR44977 16-Dec-15 2015_12 FBgn0001974 l(2)35Bd lethal (2) 35Bd http://flybase.net/reports/FBgn0001974.html FBgn0027886 protein_coding_gene "0003723=RNA binding, 0004482=mRNA (guanine-N7-)-methyltransferase activity" 0006370=7-methylguanosine mRNA capping 0005634=nucleus "C2, l(2)10408, l(2)br9, br9, CG3688, lethal 9 in the black-reduced region, BG:DS00929.5, lethal group C2" "IPR016899=mRNA (guanine-N(7))-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR004971=mRNA (guanine-N(7))-methyltransferase domain" CG3688 16-Dec-15 2015_12 "ENSDARG00000061926,ENSDARG00000070553(si:ch211-105d11.3)" YBR236C(ABD1) WBGene00006447(tag-72) ENSXETG00000014707(rnmt) ENSMUSG00000009535(Rnmt) ENSG00000101654(RNMT) "lethal,recessive,viable,visible" mesothoracic tergum FBgn0027968 l(3)S144607b lethal (3) S144607b http://flybase.net/reports/FBgn0027968.html gene "1446/07, l(3)S144607" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085231 CG34202 http://flybase.net/reports/FBgn0085231.html protein_coding_gene CG34202 16-Dec-15 2015_12 FBgn0005052 flu fluorouracil response http://flybase.net/reports/FBgn0005052.html gene 16-Dec-15 2015_12 "chemical sensitive,chemical resistant" FBgn0037756 CG8507 http://flybase.net/reports/FBgn0037756.html protein_coding_gene "0008201=heparin binding, 0050750=low-density lipoprotein particle receptor binding" "0005875=microtubule associated complex, 0005783=endoplasmic reticulum, 0012505=endomembrane system" "IPR010483=Alpha-2-macroglobulin RAP, C-terminal, IPR009066=Alpha-2-macroglobulin receptor-associated protein, domain 1" CG8507 16-Dec-15 2015_12 ENSDARG00000033604(lrpap1) WBGene00007606(C15C8.4) ENSXETG00000005500(LRPAP1) ENSMUSG00000029103(Lrpap1) ENSG00000163956(LRPAP1) viable FBgn0038147 CCHa2 CCHamide-2 http://flybase.net/reports/FBgn0038147.html FBgn0063690 protein_coding_gene 0005184=neuropeptide hormone activity 0007218=neuropeptide signaling pathway 0005615=extracellular space "CCM, BcDNA:RE10132, Drm-CCHamide-2, CG14375, CCHamide-2, CCHamide, Dm-CCHa2, CCHamide 2, CCH2" CG14375 16-Dec-15 2015_12 viable FBgn0065626 l(2)SH0794 lethal (2) SH0794 http://flybase.net/reports/FBgn0065626.html gene l(2)SH2 0794 16-Dec-15 2015_12 "lethal,recessive" FBgn0264571 CR43943 http://flybase.net/reports/FBgn0264571.html non_protein_coding_gene CR43943 16-Dec-15 2015_12 FBgn0065983 iab-5-1.s iab-5-1.s http://flybase.net/reports/FBgn0065983.html gene 5-1 s 16-Dec-15 2015_12 FBgn0052591 CG32591 http://flybase.net/reports/FBgn0052591.html "FBgn0045254, FBgn0045347" protein_coding_gene "NEST:bs18d12, NEST:bs09h01" IPR027012=Enkurin domain CG32591 16-Dec-15 2015_12 FBgn0038205 Kif19A Kinesin family member 19A ortholog http://flybase.net/reports/FBgn0038205.html protein_coding_gene "0005524=ATP binding, 0008017=microtubule binding, 0003777=microtubule motor activity" 0007018=microtubule-based movement 0005871=kinesin complex "KIF19A, DmKlp19A, DmKIF19A, Kinesin Superfamily Protein 19A, CG9913, Kif19A, KIF 19A" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001752=Kinesin motor domain, IPR027640=Kinesin-like protein" CG9913 16-Dec-15 2015_12 "ENSDARG00000053026,ENSDARG00000062606(si:dkey-26i13.8)" WBGene00002224(klp-13) "ENSXETG00000012830(),ENSXETG00000020591()" ENSMUSG00000010021(Kif19a) ENSG00000196169(KIF19) viable FBgn0013481 l(1)1PP22 lethal (1) 1PP22 http://flybase.net/reports/FBgn0013481.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" "epidermis,germline clone,ventral" FBgn0065478 l(2)SH1296 lethal (2) SH1296 http://flybase.net/reports/FBgn0065478.html gene l(2)SH2 1296 16-Dec-15 2015_12 "lethal,recessive" FBgn0032897 CG9336 http://flybase.net/reports/FBgn0032897.html FBgn0061388 protein_coding_gene BcDNA:RE71975 CG9336 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0045037 scc split central complex http://flybase.net/reports/FBgn0045037.html gene 0007420=brain development 16-Dec-15 2015_12 viable "ellipsoid body,fan-shaped body" FBgn0027173 l(2)7-1 lethal (2) 7-1 http://flybase.net/reports/FBgn0027173.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0023109 anon-10Ay anon-10Ay http://flybase.net/reports/FBgn0023109.html gene 18 16-Dec-15 2015_12 FBgn0266902 CR45362 http://flybase.net/reports/FBgn0266902.html non_protein_coding_gene CR45362 16-Dec-15 2015_12 FBgn0038076 Cyp313a4 Cyp313a4 http://flybase.net/reports/FBgn0038076.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG6802, Cyp313A4, 313a4" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG6802 16-Dec-15 2015_12 YDR402C(DIT2) FBgn0030643 CG15641 http://flybase.net/reports/FBgn0030643.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG15641 16-Dec-15 2015_12 viable DRSC19677 I 1.834890459 0.154324858 0.305928813 0.456902712 0.383329122 0.182856077 FBgn0032530 CG9263 http://flybase.net/reports/FBgn0032530.html protein_coding_gene CG9263 16-Dec-15 2015_12 viable FBgn0020874 anon-M8 anon-M8 http://flybase.net/reports/FBgn0020874.html gene 2-M8 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0032050 CG13096 http://flybase.net/reports/FBgn0032050.html protein_coding_gene 0003723=RNA binding "IPR028364=Ribosomal protein L1/ribosomal biogenesis protein, IPR023674=Ribosomal protein L1-like, IPR016094=Ribosomal protein L1, 2-layer alpha/beta-sandwich" CG13096 16-Dec-15 2015_12 WBGene00009993(F53F4.11) ENSMUSG00000005846(Rsl1d1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0004621 l(2)hs lethal heat-sensitive http://flybase.net/reports/FBgn0004621.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0020617 Rx Retinal Homeobox http://flybase.net/reports/FBgn0020617.html "FBgn0000530, FBgn0003998, FBgn0005641" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0022008=neurogenesis, 0007420=brain development" 0005634=nucleus "bk50, W60, E97, wom, wombat, CG10052, drx, Drosophila Rx, PPH17, DRx, Drx" "IPR003654=OAR domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG10052 16-Dec-15 2015_12 "ENSMUSG00000079560(Hoxa3),ENSMUSG00000079277(Hoxd3)" " embryonic stage | stage 10-11 , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage >=8 " " eye disc | primordium

, antenno-maxillary complex

, embryonic central nervous system

, embryonic procephalic segment

, labral segment

" " embryonic stage | stage 13 , larval stage | third instar , adult stage " " adult clypeo-labral primordium

, embryonic brain | medial & restricted

, larval brain | medial & restricted

, brain | dorsal & posterior & restricted

, clypeo-labral disc | restricted

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC03837 E -0.315416541 0.333019043 0.959948549 -2.256926715 0.941995902 -0.150906432 FBgn0038790 MtnC Metallothionein C http://flybase.net/reports/FBgn0038790.html protein_coding_gene 0046872=metal ion binding "0010038=response to metal ion, 0055065=metal ion homeostasis" "metallothionein, CG5097" "IPR000966=Metallothionein, family 5, Diptera" CG5097 16-Dec-15 2015_12 viable FBgn0011710 1-Sep Septin 1 http://flybase.net/reports/FBgn0011710.html "FBgn0005665, FBgn0013404, FBgn0014082, FBgn0024226" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity, 0042803=protein homodimerization activity, 0031625=ubiquitin protein ligase binding, 0005515=protein binding" "0000281=mitotic cytokinesis, 0043065=positive regulation of apoptotic process, 0007349=cellularization" "0005940=septin ring, 0031105=septin complex, 0070938=contractile ring, 0045172=germline ring canal, 0005875=microtubule associated complex" "anon-19Fa, septin 1, CG1403, unnamed, tu1, septin1, Septin-1, Diff6, Septin, iby, sep1, 38960, septin, innocent bystander" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR030379=Septin-type guanine nucleotide-binding (G) domain, IPR016491=Septin" CG1403 16-Dec-15 2015_12 "ENSXETG00000012166(SEPT2),ENSXETG00000018605(sept2)" ENSMUSG00000026276(Sept2) ENSG00000168385(SEPT2) embryonic stage -- adult stage viable FBgn0021751 3R-C 3R-C http://flybase.net/reports/FBgn0021751.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,wing vein" FBgn0063422 l(3)3450-A lethal (3) 3450-A http://flybase.net/reports/FBgn0063422.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0261834 CG42766 http://flybase.net/reports/FBgn0261834.html protein_coding_gene FBgn0261834 CG42766 16-Dec-15 2015_12 FBgn0046657 anon-38C.56 anon-38C.56 http://flybase.net/reports/FBgn0046657.html gene 38C.56 16-Dec-15 2015_12 FBgn0263948 BG00761 http://flybase.net/reports/FBgn0263948.html gene 16-Dec-15 2015_12 "long lived,starvation stress response defective,gravitaxis defective" FBgn0030991 CG7453 http://flybase.net/reports/FBgn0030991.html protein_coding_gene CG7453 16-Dec-15 2015_12 viable FBgn0261682 CG42729 http://flybase.net/reports/FBgn0261682.html "FBgn0053984, FBgn0036506, FBgn0036507" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "CG7973, CG17014, CG33984" IPR002557=Chitin binding domain CG42729 16-Dec-15 2015_12 FBgn0264705 CR43974 http://flybase.net/reports/FBgn0264705.html non_protein_coding_gene CR43974 16-Dec-15 2015_12 FBgn0041238 Gr58b Gustatory receptor 58b http://flybase.net/reports/FBgn0041238.html FBgn0034676 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG13495, 58A2, Gustatory receptor 58A.2, 58A.2, Gr58A2, GR58A.2" IPR013604=7TM chemoreceptor CG13495 16-Dec-15 2015_12 viable FBgn0267226 CR45666 http://flybase.net/reports/FBgn0267226.html non_protein_coding_gene CR45666 16-Dec-15 2015_12 FBgn0061056 l(3)S022558 lethal (3) S022558 http://flybase.net/reports/FBgn0061056.html gene 0225/58 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040063 yip3 yippee interacting protein 3 http://flybase.net/reports/FBgn0040063.html "FBgn0034836, FBgn0045256, FBgn0061446" protein_coding_gene 0004298=threonine-type endopeptidase activity 0051603=proteolysis involved in cellular protein catabolic process 0005839=proteasome core complex "CG13549, NEST:bs18b12, BcDNA:AT20887, bs18b12.y1" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR001353=Proteasome, subunit alpha/beta" CG13549 16-Dec-15 2015_12 "viable,fertile" DRSC04724 I 0.401612727 1.536688449 0.18715439 -0.504370684 1.472119323 0.98469622 FBgn0266376 CR45018 http://flybase.net/reports/FBgn0266376.html non_protein_coding_gene CR45018 16-Dec-15 2015_12 FBgn0086298 camo camouflaged http://flybase.net/reports/FBgn0086298.html gene 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0022738 cnr censor http://flybase.net/reports/FBgn0022738.html gene 16-Dec-15 2015_12 FBgn0033275 CG14756 http://flybase.net/reports/FBgn0033275.html protein_coding_gene CG14756 16-Dec-15 2015_12 "viable,fertile" FBgn0038715 CG7333 http://flybase.net/reports/FBgn0038715.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG7333 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "partially lethal - majority die,some die during pupal stage" FBgn0267218 CR45658 http://flybase.net/reports/FBgn0267218.html non_protein_coding_gene CR45658 16-Dec-15 2015_12 FBgn0260794 ctrip circadian trip http://flybase.net/reports/FBgn0260794.html "FBgn0037277, FBgn0037278" protein_coding_gene "0016922=ligand-dependent nuclear receptor binding, 0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0042753=positive regulation of circadian rhythm, 0022008=neurogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0045732=positive regulation of protein catabolic process" 0005634=nucleus "CG14656, CG42574, CG17735" "IPR004170=WWE domain, IPR011989=Armadillo-like helical, IPR000569=HECT domain, IPR016024=Armadillo-type fold, IPR018123=WWE domain, subgroup" CG42574 16-Dec-15 2015_12 ENSDARG00000061397(si:ch211-272f3.4) YKL010C(UFD4) ENSXETG00000014757(TRIP12) ENSMUSG00000026219(Trip12) ENSG00000153827(TRIP12) DRSC12242 E 0.693357252 -0.927077153 0.017965532 -3.364668582 -0.48129339 -0.801808619 FBgn0069173 mcl(3)Z0317 mcl(3)Z0317 http://flybase.net/reports/FBgn0069173.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0264960 CR44129 http://flybase.net/reports/FBgn0264960.html non_protein_coding_gene CR44129 16-Dec-15 2015_12 FBgn0005245 l(3)R142 lethal of Roberts 142 http://flybase.net/reports/FBgn0005245.html gene l(3)B142 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0042646 elav::Sxl elav::Sxl http://flybase.net/reports/FBgn0042646.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0000805 fs(1)de16 female sterile (1) defective eggs 16 http://flybase.net/reports/FBgn0000805.html gene de16 16-Dec-15 2015_12 female sterile "endochorion,dorsal appendage,chorion" FBgn0039839 ppk24 pickpocket 24 http://flybase.net/reports/FBgn0039839.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "pickpocket 24, ppk24, CG15555" "IPR020903=Na+ channel, amiloride-sensitive, conserved site, IPR001873=Na+ channel, amiloride-sensitive" CG15555 16-Dec-15 2015_12 viable DRSC15093 I 1.06605634 4.087822039 1.334483322 0.343195714 0.426111986 -0.118601551 FBgn0052695 CG32695 http://flybase.net/reports/FBgn0052695.html "FBgn0030155, FBgn0046996" protein_coding_gene "BcDNA:RH68724, CG15246" CG32695 16-Dec-15 2015_12 viable FBgn0067652 sd-3 sd-3 http://flybase.net/reports/FBgn0067652.html gene "0007270=neuron-neuron synaptic transmission, 0042331=phototaxis" complementation group 3 16-Dec-15 2015_12 "lethal,neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032964 CG11630 http://flybase.net/reports/FBgn0032964.html protein_coding_gene 0003824=catalytic activity "0008152=metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space gi7302136 "IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG11630 16-Dec-15 2015_12 viable FBgn0063420 l(3)3450-C lethal (3) 3450-C http://flybase.net/reports/FBgn0063420.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0263618 CR43627 http://flybase.net/reports/FBgn0263618.html non_protein_coding_gene lincRNA.437 CR43627 16-Dec-15 2015_12 FBgn0051520 CG31520 http://flybase.net/reports/FBgn0051520.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265684 CR44491 http://flybase.net/reports/FBgn0265684.html non_protein_coding_gene CR44491 16-Dec-15 2015_12 FBgn0263596 CG43618 http://flybase.net/reports/FBgn0263596.html protein_coding_gene CG43618 16-Dec-15 2015_12 FBgn0260455 CG10332 http://flybase.net/reports/FBgn0260455.html "FBgn0034881, FBgn0045894, FBgn0045895, FBgn0045896, FBgn0063722, FBgn0069058" protein_coding_gene "anon-WO0153538.58, anon-WO0153538.57, CG10332-ORFA, BcDNA:AT19986, anon-WO0153538.56" CG10332 16-Dec-15 2015_12 FBgn0065965 l(2)SH0022 lethal (2) SH0022 http://flybase.net/reports/FBgn0065965.html gene l(2)SH2 0022 16-Dec-15 2015_12 "lethal,recessive" FBgn0038052 CG5538 http://flybase.net/reports/FBgn0038052.html FBgn0044542 protein_coding_gene "anon-WO0140519.84, bs11a11.y1" CG5538 16-Dec-15 2015_12 viable FBgn0013812 Dhc93AB Dynein heavy chain at 93AB http://flybase.net/reports/FBgn0013812.html protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity, 0003777=microtubule motor activity, 0003774=motor activity, 0042623=ATPase activity, coupled" "0007018=microtubule-based movement, 0007605=sensory perception of sound" "0005875=microtubule associated complex, 0005858=axonemal dynein complex" "Dhc, CG3723, dhc, DHC, Dhc 93AB, unnamed, dynein-related heavy chain polypeptide, dhc93AB" "IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR011704=ATPase, dynein-related, AAA domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR004273=Dynein heavy chain domain, IPR013594=Dynein heavy chain, domain-1, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013602=Dynein heavy chain, domain-2" CG3723 16-Dec-15 2015_12 ENSDARG00000062630 ENSXETG00000007515(DNAH11) ENSMUSG00000056752(Dnahc9) "ENSG00000187775(DNAH17),ENSG00000007174(DNAH9)" " adult stage | female , embryonic stage , adult stage | male " "auditory perception defective,neurophysiology defective,viable" FBgn0002578 Kaz-m1 Kazal-type protease inhibitor m1 http://flybase.net/reports/FBgn0002578.html FBgn0063010 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0030162=regulation of proteolysis "CG8342, HLHm1, m1, lincRNA.856, E(spl)-m1, E(spl) region transcript m1, BcDNA:RE44854, E(spl)m1" IPR002350=Kazal domain CG8342 16-Dec-15 2015_12 " embryonic stage , embryonic stage | 6-10 hr " " posterior embryonic/larval midgut | anterior

, anterior embryonic/larval midgut | posterior

, embryonic/larval proventriculus

" viable FBgn0004563 l(3)63Bi lethal (3) 63Bi http://flybase.net/reports/FBgn0004563.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035137 CG1233 http://flybase.net/reports/FBgn0035137.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1233 16-Dec-15 2015_12 viable FBgn0038273 CG14860 http://flybase.net/reports/FBgn0038273.html protein_coding_gene 0003676=nucleic acid binding "IPR006612=Zinc finger, C2CH-type" CG14860 16-Dec-15 2015_12 viable FBgn0004184 snRNA:U1:82Ec small nuclear RNA U1 at 82Ec http://flybase.net/reports/FBgn0004184.html FBgn0003917 pseudogene_attribute "snRNA:U1, U1 82E(pDm6Y), U1-82.2, U1, snRNA-U1-82.2, U1a-82Ec, U1snRNA82Ec, 82.2, U1 snRNA" 16-Dec-15 2015_12 FBgn0003665 tar tarry http://flybase.net/reports/FBgn0003665.html gene ta 16-Dec-15 2015_12 "viable,reduced" "femur,tibia,leg,coxa" FBgn0052362 tRNA:CR32362 transfer RNA:CR32362 http://flybase.net/reports/FBgn0052362.html "FBgn0011907, FBgn0060160" tRNA_gene "0033420=CUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Leu][[2]], tRNA:leu2:66B, CR32362, chr3L.trna40-LeuCAG, AE002602.trna6-LeuCAG, tRNA:L2:66B, transfer RNA:leu2:66B, tRNA:L:CAG:AE002602-b" CR32362 16-Dec-15 2015_12 FBgn0014158 eppy epilated periorbitally http://flybase.net/reports/FBgn0014158.html gene 16-Dec-15 2015_12 FBgn0013467 igl igloo http://flybase.net/reports/FBgn0013467.html protein_coding_gene "0032027=myosin light chain binding, 0005516=calmodulin binding" 0005938=cell cortex "Igl, CG18285, invertebrate GAP-43-like" "IPR000048=IQ motif, EF-hand binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG18285 16-Dec-15 2015_12 " embryonic stage--pupal stage , embryonic stage | stage >=15 , embryonic stage -- adult stage " " embryonic peripheral nervous system

, central nervous system

" DRSC28961 K 0.553638708 -0.944848549 0.319138291 0.883986508 -0.378895205 -2.753896913 FBgn0065701 l(2)SH0621 lethal (2) SH0621 http://flybase.net/reports/FBgn0065701.html gene l(2)SH2 0621 16-Dec-15 2015_12 "lethal,recessive" FBgn0265871 CR44660 http://flybase.net/reports/FBgn0265871.html non_protein_coding_gene CR44660 16-Dec-15 2015_12 FBgn0036858 CG14088 http://flybase.net/reports/FBgn0036858.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH199 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG14088 16-Dec-15 2015_12 viable FBgn0044378 anon-AE003538.1 anon-AE003538.1 http://flybase.net/reports/FBgn0044378.html gene unnamed 16-Dec-15 2015_12 FBgn0053627 CG33627 http://flybase.net/reports/FBgn0053627.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33627 16-Dec-15 2015_12 FBgn0038652 CG7720 http://flybase.net/reports/FBgn0038652.html FBgn0064849 protein_coding_gene 0008507=sodium:iodide symporter activity 0055085=transmembrane transport 0016020=membrane "BcDNA:RH05973, dSLC5A1, ORE-8" "IPR001734=Sodium/solute symporter, IPR019900=Sodium/solute symporter, subgroup" CG7720 16-Dec-15 2015_12 YHL016C(DUR3) "viable,fertile" FBgn0032779 CG16771 http://flybase.net/reports/FBgn0032779.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR001952=Alkaline phosphatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain" CG16771 16-Dec-15 2015_12 YDR481C(PHO8) "viable,flightless" FBgn0036222 SdhAL "Succinate dehydrogenase, subunit A (flavoprotein)-like" http://flybase.net/reports/FBgn0036222.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0008177=succinate dehydrogenase (ubiquinone) activity" "0006099=tricarboxylic acid cycle, 0022900=electron transport chain" "0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)" "Succinate dehydrogenase Flavoprotein subunit, CG5718, Succinate dehydrogenase [ubiquinone] flavoprotein subunit, DHSA" "IPR027477=Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain, IPR015939=Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal, IPR003953=FAD-dependent oxidoreductase 2, FAD binding domain, IPR011281=Succinate dehydrogenase, flavoprotein subunit, IPR003952=Fumarate reductase/succinate dehydrogenase, FAD-binding site, IPR014006=Succinate dehydrogenase/fumarate reductase, flavoprotein subunit" CG5718 16-Dec-15 2015_12 viable FBgn0030961 CG7058 http://flybase.net/reports/FBgn0030961.html protein_coding_gene "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG7058 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC20021 K -0.128695932 -0.243223875 0.443894608 0.120395991 1.955790064 0.940835089 FBgn0036442 CG13473 http://flybase.net/reports/FBgn0036442.html protein_coding_gene "0015036=disulfide oxidoreductase activity, 0015035=protein disulfide oxidoreductase activity" "0045454=cell redox homeostasis, 0006662=glycerol ether metabolic process" "IPR017937=Thioredoxin, conserved site, IPR013766=Thioredoxin domain, IPR005746=Thioredoxin, IPR012336=Thioredoxin-like fold" CG13473 16-Dec-15 2015_12 viable FBgn0011280 Obp19d Odorant-binding protein 19d http://flybase.net/reports/FBgn0011280.html "FBgn0062913, FBgn0063177" protein_coding_gene "0008145=phenylalkylamine binding, 0005550=pheromone binding, 0005549=odorant binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "Pbprp2, BcDNA:RH68082, DmelObp19d, PBPRP2, pbprp2, 19d, pbprp-2, PBPRP-2, CG1668, Obp19d, PBP2, PB-PRP2, BcDNA:HL07789, Pheromone-binding protein-related protein 2" IPR006170=Pheromone/general odorant binding protein CG1668 16-Dec-15 2015_12 adult stage " maxillary palpus

, sensillum coeloconica of antennal segment 3

, taste-sensory region glomerulus

, sensillum basiconicum of antennal segment 3

, antennal segment 3

, proboscis

, sensillum trichodeum of antennal segment 3

, ventral cibarial sense organ

" viable DRSC20569 K 0.541956213 -0.080552862 -0.000989213 0.217615473 1.100732064 1.846486009 FBgn0085805 CR41583 http://flybase.net/reports/FBgn0085805.html FBan0041583 rRNA_gene CR41583 16-Dec-15 2015_12 FBgn0003260 Rm4 Ring magnifier on 4 http://flybase.net/reports/FBgn0003260.html gene 16-Dec-15 2015_12 FBgn0020902 Su(osk)3-O26 Suppressor of oskar 3-O26 http://flybase.net/reports/FBgn0020902.html gene O26 16-Dec-15 2015_12 FBgn0000875 fs(1)M73 female sterile (1) M73 http://flybase.net/reports/FBgn0000875.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0065719 l(2)SH0573 lethal (2) SH0573 http://flybase.net/reports/FBgn0065719.html gene l(2)SH2 0573 16-Dec-15 2015_12 "lethal,recessive" FBgn0262477 FoxP Forkhead box P http://flybase.net/reports/FBgn0262477.html "FBgn0037735, FBgn0052937" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0035106=operant conditioning, 0006355=regulation of transcription, DNA-templated, 0040011=locomotion, 0045433=male courtship behavior, veined wing generated song production" 0005634=nucleus "Dmcg16899, DmFoxP, CG43067, forkhead domain 85E, dFoxP, CG32937, CG16899, fd85E, FoxP" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR001766=Fork head domain" CG43067 16-Dec-15 2015_12 ENSMUSG00000039521(Foxp3) ENSG00000049768(FOXP3) DRSC29407 K -0.617406818 -0.26338598 0.731750493 -0.091460133 2.468415972 0.226901796 FBgn0267934 CR46214 http://flybase.net/reports/FBgn0267934.html non_protein_coding_gene lincRNA.586 CR46214 16-Dec-15 2015_12 FBgn0032629 beat-IIIc beat-IIIc http://flybase.net/reports/FBgn0032629.html "FBgn0032630, FBgn0061407" protein_coding_gene "0016201=synaptic target inhibition, 0008045=motor neuron axon guidance, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules" 0005576=extracellular region "beat IIIc, CG15138, CG6365, Beat-IIIC, Beat-IIIc, BcDNA:RE14414" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR007110=Immunoglobulin-like domain" CG15138 16-Dec-15 2015_12 viable FBgn0053306 CG33306 http://flybase.net/reports/FBgn0053306.html "FBgn0028921, FBgn0064942" protein_coding_gene "BcDNA:GM14937, BG:DS00941.11, DS00941.11, CG16887" IPR010562=Haemolymph juvenile hormone binding CG33306 16-Dec-15 2015_12 viable FBgn0001259 in inturned http://flybase.net/reports/FBgn0001259.html protein_coding_gene "0001736=establishment of planar polarity, 0001737=establishment of imaginal disc-derived wing hair orientation, 0035316=non-sensory hair organization, 0007163=establishment or maintenance of cell polarity" 0005886=plasma membrane "transcript B, CG16993, intwined, B" IPR001478=PDZ domain CG16993 16-Dec-15 2015_12 ENSXETG00000022533(INTU) ENSMUSG00000060798(Intu) ENSG00000164066(INTU) "viable,fertile,visible,recessive,cold sensitive,wild-type,planar polarity defective,heat sensitive,lethal,cell autonomous,somatic clone" "macrochaeta,cold sensitive,wing cell,wing hair,microchaeta & wing,wing hair & 1st posterior cell,macrochaeta & adult thorax,microchaeta & adult thorax,microchaeta & leg,bract,wing,heat sensitive,supernumerary,cell autonomous,somatic clone" FBgn0261597 RpS26 Ribosomal protein S26 http://flybase.net/reports/FBgn0261597.html "FBgn0005520, FBgn0002008, FBgn0002598, FBgn0004413, FBgn0003280, FBgn0004088, FBgn0011775, FBgn0025235" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "Rps26, l(2)36Fa, unnamed, M[[s]], anon-EST:fe2A3, M(2)36F, M(2)S13, CG10305, rpS26, rpS31, l(2)04553, M(2)m, Minute (2) 36F, ribosomal protein S31, anon-fast-evolving-2A3" IPR000892=Ribosomal protein S26e CG10305 16-Dec-15 2015_12 "ENSDARG00000037071(rps26),ENSDARG00000030408(rps26l)" "YER131W(RPS26B),YGL189C(RPS26A)" WBGene00004495(rps-26) ENSXETG00000009458(Q6DDC9_XENTR) "ENSMUSG00000025362(Rps26),ENSMUSG00000059775(Rps26-ps1)" "ENSG00000197728(RPS26),ENSG00000196656,ENSG00000212994,ENSG00000204652,ENSG00000196933" DRSC03420 IEK -2.27667225 -1.8482029 0.627828527 -3.618983175 -0.17589863 2.754710464 FBgn0085502 CG40624 http://flybase.net/reports/FBgn0085502.html FBan0040624 protein_coding_gene 16-Dec-15 2015_12 FBgn0028882 tRNA:P:35Bd tRNA:P:35Bd http://flybase.net/reports/FBgn0028882.html "FBgn0051985, FBgn0060123" tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:pro, chr2L.trna18-ProAGG, BG:DS04641.2, tRNA:P:AGG:AE002690-a, CR31985, AE002690.trna9-ProAGG" CR31985 16-Dec-15 2015_12 FBgn0265086 CR44197 http://flybase.net/reports/FBgn0265086.html non_protein_coding_gene CR44197 16-Dec-15 2015_12 FBgn0040772 CG12430 http://flybase.net/reports/FBgn0040772.html protein_coding_gene 16-Dec-15 2015_12 FBgn0069928 CG41123 http://flybase.net/reports/FBgn0069928.html FBan0041123 protein_coding_gene 16-Dec-15 2015_12 FBgn0265711 CR44518 http://flybase.net/reports/FBgn0265711.html non_protein_coding_gene "incRNA.445, lincRNA.445" CR44518 16-Dec-15 2015_12 FBgn0266881 CR45342 http://flybase.net/reports/FBgn0266881.html non_protein_coding_gene CR45342 16-Dec-15 2015_12 FBgn0261832 CG42764 http://flybase.net/reports/FBgn0261832.html protein_coding_gene IPR014044=CAP domain CG42764 16-Dec-15 2015_12 FBgn0061045 l(3)S023637a lethal (3) S023637a http://flybase.net/reports/FBgn0061045.html gene 0236/37 16-Dec-15 2015_12 "lethal,recessive" FBgn0086707 ncm nucampholin http://flybase.net/reports/FBgn0086707.html "FBgn0065582, FBgn0032678" protein_coding_gene "0003723=RNA binding, 0005515=protein binding" 0006909=phagocytosis 0005681=spliceosomal complex "CG12750, l(2)SH0931, lethal (2) SH0931, E-2a, l(2)SH2 0931, nucampholin" "IPR003890=MIF4G-like, type 3, IPR016021=MIF4G-like domain, IPR003891=Initiation factor eIF-4 gamma, MA3, IPR016024=Armadillo-type fold" CG12750 16-Dec-15 2015_12 ENSDARG00000014008(zgc:153452) YGR278W(CWC22) WBGene00002957(let-858) ENSXETG00000014099(CWC22) "ENSMUSG00000027014(Cwc22),ENSMUSG00000075239,ENSMUSG00000079249,ENSMUSG00000075238,ENSMUSG00000079250,ENSMUSG00000079247,ENSMUSG00000075237,ENSMUSG00000079248" ENSG00000163510(CWC22) DRSC02179 I -0.785395089 1.633931138 1.136503344 0.429024101 -0.693422318 -1.155720537 FBgn0065540 l(2)SH1061 lethal (2) SH1061 http://flybase.net/reports/FBgn0065540.html gene l(2)SH2 1061 16-Dec-15 2015_12 "lethal,recessive" FBgn0020772 vta vena transversa interrupta http://flybase.net/reports/FBgn0020772.html gene 16-Dec-15 2015_12 FBgn0005360 sup superwith http://flybase.net/reports/FBgn0005360.html gene 16-Dec-15 2015_12 body color defective trident FBgn0005463 l(1)ts66 lethal (1) ts66 http://flybase.net/reports/FBgn0005463.html gene 16-Dec-15 2015_12 "learning defective,lethal,heat sensitive,chemical sensitive,uncoordinated,gravitaxis defective,phototaxis defective,locomotor behavior defective,flight defective" FBgn0014042 Su(tor)2-113 Su(tor)2-113 http://flybase.net/reports/FBgn0014042.html gene 16-Dec-15 2015_12 FBgn0051556 CG31556 http://flybase.net/reports/FBgn0051556.html protein_coding_gene mdcds_43655 16-Dec-15 2015_12 viable DRSC22177 IEK -1.568126033 2.028385134 2.089500495 1.741794365 2.326056651 0.104316319 FBgn0260968 CG42591 http://flybase.net/reports/FBgn0260968.html protein_coding_gene CG42591 16-Dec-15 2015_12 FBgn0033362 CG8172 http://flybase.net/reports/FBgn0033362.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP32, c-SP32" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG8172 16-Dec-15 2015_12 "ENSXETG00000006297(Q6DJ90_XENTR),ENSXETG00000023578(),ENSXETG00000001793(),ENSXETG00000005963(),ENSXETG00000009052(OVCH2)" FBgn0014228 l(2)31Eg lethal (2) 31Eg http://flybase.net/reports/FBgn0014228.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037669 Ibf2 Insulator binding factor 2 http://flybase.net/reports/FBgn0037669.html protein_coding_gene "0043565=sequence-specific DNA binding, 0005515=protein binding, 0046982=protein heterodimerization activity, 0043035=chromatin insulator sequence binding" "0010468=regulation of gene expression, 0031937=positive regulation of chromatin silencing" 0005634=nucleus CG9740 CG9740 16-Dec-15 2015_12 "homeotic,partially lethal - majority live,male sterile,short lived,dominant,viable" "abdominal sternite 7,female limited" FBgn0266437 CG45067 http://flybase.net/reports/FBgn0266437.html FBgn0035399 protein_coding_gene 0016021=integral component of membrane CG14955 IPR008795=Prominin CG45067 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0036769 Tsp74F Tetraspanin 74F http://flybase.net/reports/FBgn0036769.html protein_coding_gene 0016021=integral component of membrane "CG5492, Dm.Tsp74F" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG5492 16-Dec-15 2015_12 "ENSDARG00000038288(cd151),ENSDARG00000001781(si:dkey-21h14.7),ENSDARG00000068629(cd151l)" "ENSXETG00000019035(CD151),ENSXETG00000016650(TSPAN11)" "ENSMUSG00000025510(Cd151),ENSMUSG00000030351(Tspan11)" "ENSG00000110900(TSPAN11),ENSG00000177697(CD151)" "lethal,maternal effect,some die during embryonic stage,viable" "egg,maternal effect" FBgn0085316 CG34287 http://flybase.net/reports/FBgn0085316.html protein_coding_gene CG34287 16-Dec-15 2015_12 FBgn0000756 fs(1)A456 female sterile (1) A456 http://flybase.net/reports/FBgn0000756.html gene 0048477=oogenesis "fs(1)456v24, fs(1)456, fs(1)M66" 16-Dec-15 2015_12 "female sterile,recessive,female sterile soma-dependent" egg FBgn0036394 CG9040 http://flybase.net/reports/FBgn0036394.html FBgn0063088 protein_coding_gene BcDNA:LP10528 CG9040 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0005762 l(1)TK409 lethal (1) TK409 http://flybase.net/reports/FBgn0005762.html gene l409 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0030495 CG11816 http://flybase.net/reports/FBgn0030495.html protein_coding_gene CG11816 16-Dec-15 2015_12 viable DRSC19428 IE -2.00389823 -0.332720571 -1.79439505 -0.703366178 1.271309279 0.124621133 FBgn0030346 CG11802 http://flybase.net/reports/FBgn0030346.html protein_coding_gene "IPR018780=Tumour suppressor protein, LOH1CR12" CG11802 16-Dec-15 2015_12 WBGene00019126(F59E12.11) ENSMUSG00000042992(Loh12cr1) ENSG00000165714(LOH12CR1) viable FBgn0024541 l(3)L2100 lethal (3) L2100 http://flybase.net/reports/FBgn0024541.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005155 l(2)G99 lethal (2) G99 http://flybase.net/reports/FBgn0005155.html gene 16-Dec-15 2015_12 lethal FBgn0003595 Su(var)3-4 Suppressor of variegation 3-4 http://flybase.net/reports/FBgn0003595.html gene "Su-var(3)4, Su(var)3-401, Suvar(3)4, Su-var(3)401" 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0044475 EP1463 EP1463 http://flybase.net/reports/FBgn0044475.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0031628 CG3294 http://flybase.net/reports/FBgn0031628.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0046872=metal ion binding, 0003723=RNA binding" "0042060=wound healing, 0000398=mRNA splicing, via spliceosome" 0005681=spliceosomal complex cg3294 "IPR009145=U2 auxiliary factor small subunit, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000571=Zinc finger, CCCH-type" CG3294 16-Dec-15 2015_12 ENSDARG00000058448(zrsr2) "ENSMUSG00000031370(Zrsr2),ENSMUSG00000044068(Zrsr1)" "ENSG00000169249(ZRSR2),ENSG00000212643" "viable,fertile" DRSC00590 K -0.116433967 0.155967847 -0.180058277 0.540385362 -3.209488663 0.226632257 FBgn0039288 CG13653 http://flybase.net/reports/FBgn0039288.html protein_coding_gene CG13653 16-Dec-15 2015_12 viable FBgn0265724 CR44531 http://flybase.net/reports/FBgn0265724.html non_protein_coding_gene "incRNA.419, lincRNA.419" CR44531 16-Dec-15 2015_12 FBgn0001005 Fs(2)Vaj Female sterile (2) Vaja http://flybase.net/reports/FBgn0001005.html gene "Fs(2)Sz13, Vaja" 16-Dec-15 2015_12 "female sterile,dominant" FBgn0016007 l(3)63Fa lethal (3) 63Fa http://flybase.net/reports/FBgn0016007.html gene l(3)SH8 16-Dec-15 2015_12 "lethal,recessive" FBgn0020886 Sxl::U2af65 Sxl::U2af65 http://flybase.net/reports/FBgn0020886.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,male,viable,female" FBgn0014942 anon-98Dc anon-98Dc http://flybase.net/reports/FBgn0014942.html gene unnamed 16-Dec-15 2015_12 FBgn0035548 CG15023 http://flybase.net/reports/FBgn0035548.html protein_coding_gene CG15023 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0043021 snRNA:U5:38ABb snRNA:U5:38ABb http://flybase.net/reports/FBgn0043021.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "K2, U5var:38ABb, snRNA:U5, dU5, small nuclear RNA U5, U5, U5 snRNA, CR32880, U5-38ABb, U5 small nuclear RNA, 38A U5, U5 38ABb, U5snRNA, U5:38ABb" CR32880 16-Dec-15 2015_12 FBgn0053095 CG33095 http://flybase.net/reports/FBgn0053095.html "FBgn0039275, FBgn0039276" protein_coding_gene "CG11935, FBgn0039275, CG11938" CG33095 16-Dec-15 2015_12 viable FBgn0262570 CG43110 http://flybase.net/reports/FBgn0262570.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis MB7.chr2R.pasa.4777 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site" CG43110 16-Dec-15 2015_12 FBgn0069973 CG40485 http://flybase.net/reports/FBgn0069973.html FBan0040485 protein_coding_gene 0016491=oxidoreductase activity "0022008=neurogenesis, 0008152=metabolic process" "FOHSDR, unnamed" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG40485 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0087016 l(3)61Dd lethal (3) 61Dd http://flybase.net/reports/FBgn0087016.html gene 16-Dec-15 2015_12 lethal FBgn0037777 CG11722 http://flybase.net/reports/FBgn0037777.html FBgn0063333 protein_coding_gene 0032981=mitochondrial respiratory chain complex I assembly BcDNA:AT14909 IPR009622=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 CG11722 16-Dec-15 2015_12 ENSXETG00000022674(NDUFAF4) ENSMUSG00000028261(Ndufaf4) ENSG00000123545(NDUFAF4) "viable,visible" mesothoracic tergum FBgn0261683 B9d2 B9d2 http://flybase.net/reports/FBgn0261683.html "FBgn0031783, FBan0009227" protein_coding_gene 0035869=ciliary transition zone "CG9227, CG42730" IPR010796=B9 domain CG42730 16-Dec-15 2015_12 FBgn0267746 CR46077 http://flybase.net/reports/FBgn0267746.html non_protein_coding_gene CR46077 16-Dec-15 2015_12 FBgn0036709 Or74a Odorant receptor 74a http://flybase.net/reports/FBgn0036709.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR26, 74a, 74A.1, CG13726" "IPR004117=Olfactory receptor, Drosophila" CG13726 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0034269 CG6406 http://flybase.net/reports/FBgn0034269.html protein_coding_gene IPR018619=Hyccin CG6406 16-Dec-15 2015_12 "ENSDARG00000026762(zgc:77228),ENSDARG00000059324(zgc:158316)" WBGene00017037(D1069.3) ENSXETG00000005936(FAM126A) "ENSMUSG00000028995(Fam126a),ENSMUSG00000038174(Fam126b)" "ENSG00000122591(FAM126A),ENSG00000155744(FAM126B)" FBgn0261374 Phox Phenol oxidase http://flybase.net/reports/FBgn0261374.html "FBgn0000165, FBgn0003081" gene "0004097=catechol oxidase activity, 0004503=monophenol monooxygenase activity" "PHOX, phenol oxidase" 16-Dec-15 2015_12 "electrophoretic variant,fast,slow,intermediate" FBgn0263849 CG43710 http://flybase.net/reports/FBgn0263849.html protein_coding_gene CG43710 16-Dec-15 2015_12 FBgn0266940 CR45391 http://flybase.net/reports/FBgn0266940.html pseudogene_attribute CR45391 16-Dec-15 2015_12 FBgn0267730 CR46061 http://flybase.net/reports/FBgn0267730.html non_protein_coding_gene CR46061 16-Dec-15 2015_12 FBgn0037798 CG12817 http://flybase.net/reports/FBgn0037798.html FBgn0063672 protein_coding_gene 0005509=calcium ion binding BcDNA:RE53107 "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG12817 16-Dec-15 2015_12 ENSDARG00000039757(mcfd2) ENSXETG00000022745(mcfd2) ENSMUSG00000024150(Mcfd2) ENSG00000180398(MCFD2) viable FBgn0011484 l(3)neo54 lethal (3) neo54 http://flybase.net/reports/FBgn0011484.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085757 CR40621 http://flybase.net/reports/FBgn0085757.html FBan0040621 rRNA_gene CR40621 16-Dec-15 2015_12 FBgn0036463 Reck Reversion-inducing-cysteine-rich protein with kazal motifs http://flybase.net/reports/FBgn0036463.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "CG5392, reversion-inducing-cysteine-rich protein with kazal motifs, RECK" "IPR002350=Kazal domain, IPR001007=VWFC domain" CG5392 16-Dec-15 2015_12 ENSMUSG00000028476(Reck) ENSG00000122707(RECK) FBgn0001889 l(2)21Dc lethal (2) 21Dc http://flybase.net/reports/FBgn0001889.html gene "l(2)neh3, l(2)neh-3" 16-Dec-15 2015_12 lethal FBgn0261702 CR42738 http://flybase.net/reports/FBgn0261702.html non_protein_coding_gene CR42738 16-Dec-15 2015_12 FBgn0063416 l(3)3450-G lethal (3) 3450-G http://flybase.net/reports/FBgn0063416.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0263322 CG43403 http://flybase.net/reports/FBgn0263322.html protein_coding_gene CG43403 16-Dec-15 2015_12 FBgn0262891 CG43246 http://flybase.net/reports/FBgn0262891.html protein_coding_gene CG43246 16-Dec-15 2015_12 FBgn0052588 CG32588 http://flybase.net/reports/FBgn0052588.html "FBgn0045380, FBgn0061427" protein_coding_gene "BcDNA:AT31812, bs07c08.y1, NEST:bs07c08" CG32588 16-Dec-15 2015_12 viable FBgn0040522 CG10928 http://flybase.net/reports/FBgn0040522.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260564 MENE(3R)-A http://flybase.net/reports/FBgn0260564.html gene MENE (3R)-A 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0066353 l(3)99DEb lethal (3) 99DEb http://flybase.net/reports/FBgn0066353.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003517 sta stubarista http://flybase.net/reports/FBgn0003517.html "FBgn0010239, FBgn0026668, FBgn0029057" protein_coding_gene "0043022=ribosome binding, 0003735=structural constituent of ribosome" "0007052=mitotic spindle organization, 0000028=ribosomal small subunit assembly, 0000447=endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0000461=endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0006407=rRNA export from nucleus, 0000022=mitotic spindle elongation, 0006412=translation" "0030686=90S preribosome, 0022627=cytosolic small ribosomal subunit, 0005875=microtubule associated complex, 0005840=ribosome" "Sta, Laminin-receptor, anon-EST:Liang-2.56, Lam-r, chrX:1339078..1339216, 37LRP/p40, Ribosomal protein SA, Rp 40, P40, STA, l(1)2Af, Laminin receptor, k14, Stubarista, Sa, RpSA, unnamed, Rp40, CG14792, l(1)G0448, clone 2.56, l(1)G0130, EG:80H7.6" "IPR001865=Ribosomal protein S2, IPR023591=Ribosomal protein S2, flavodoxin-like domain, IPR027498=Ribosomal protein S2, eukaryotic, IPR018130=Ribosomal protein S2, conserved site, IPR005707=Ribosomal protein S2, eukaryotic/archaeal" CG14792 16-Dec-15 2015_12 ENSDARG00000019181(rpsa) "YLR048W(RPS0B),YGR214W(RPS0A)" WBGene00004469(rps-0) ENSXETG00000027344(rpsa) "ENSMUSG00000032518(Rpsa),ENSMUSG00000047676(Rpsa-ps10)" "ENSG00000168028(RPSA),ENSG00000205246,ENSG00000214896,ENSG00000214629" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,visible,viable,female sterile,aging defective,lethal - all die before end of pupal stage,some die during pupal stage" "antenna,macrochaeta,arista,embryonic/larval lymph gland,primary lobe of embryonic/larval lymph gland" DRSC18838 K -1.492578197 -0.9814571 0.763278568 -1.159016268 0.896750291 3.086639783 FBgn0038199 CCHa1 CCHamide-1 http://flybase.net/reports/FBgn0038199.html protein_coding_gene 0005184=neuropeptide hormone activity 0007218=neuropeptide signaling pathway 0005615=extracellular space "CCHamide, CG14358, CCHamide 1, CCH1, Dm-CCHa1, CCHamide-1, CCM, Drm-CCHamide-1, CCHamide1" CG14358 16-Dec-15 2015_12 lethal FBgn0267774 CR46105 http://flybase.net/reports/FBgn0267774.html non_protein_coding_gene CR46105 16-Dec-15 2015_12 FBgn0011621 l(1)K49h10-5 lethal (1) K49h10-5 http://flybase.net/reports/FBgn0011621.html gene 16-Dec-15 2015_12 lethal FBgn0043864 pf-2 pairing failure-2 http://flybase.net/reports/FBgn0043864.html gene 0007141=male meiosis I "CG2, Complementation group 2" 16-Dec-15 2015_12 FBgn0031399 mio missing oocyte http://flybase.net/reports/FBgn0031399.html FBgn0031400 protein_coding_gene 0051082=unfolded protein binding "0006302=double-strand break repair, 0007294=germarium-derived oocyte fate determination, 0030716=oocyte fate determination, 0006457=protein folding, 0040020=regulation of meiotic nuclear division, 1903432=regulation of TORC1 signaling, 0010507=negative regulation of autophagy, 0007293=germarium-derived egg chamber formation" "0044754=autolysosome, 0043234=protein complex, 0005764=lysosome, 0035859=Seh1-associated complex" "SEA4, CG15384, FBtr0077835, CG7074, Mio" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG7074 16-Dec-15 2015_12 ENSDARG00000010995(mios) YBL104C() ENSXETG00000007293() ENSMUSG00000042447(Mios) ENSG00000164654(MIOS) "female sterile,recessive,partially lethal - majority die,some die during pupal stage" "nurse cell,egg chamber,oocyte,centriole,microtubule,oocyte & germarium,synaptonemal complex & presumptive oocyte & germarium region 2a,presumptive oocyte & pachytene,presumptive oocyte & zygotene" FBgn0039619 CG14519 http://flybase.net/reports/FBgn0039619.html protein_coding_gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0022173 l(2)k05421 lethal (2) k05421 http://flybase.net/reports/FBgn0022173.html gene l(2)k05433 16-Dec-15 2015_12 "lethal,recessive" FBgn0032751 CG17343 http://flybase.net/reports/FBgn0032751.html protein_coding_gene CG17343 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0050080 CG30080 http://flybase.net/reports/FBgn0050080.html "FBgn0034039, FBgn0063021, FBgn0064859" protein_coding_gene "BcDNA:RE70859, CG12965, BcDNA:RE42467" CG30080 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC05571 IK 0.734612714 1.501406068 0.168046301 0.117828075 0.703203324 2.191254959 FBgn0060434 l(3)S125310b lethal (3) S125310b http://flybase.net/reports/FBgn0060434.html gene 1253/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0085207 CG34178 http://flybase.net/reports/FBgn0085207.html protein_coding_gene IPR029277=Single domain Von Willebrand factor type C domain CG34178 16-Dec-15 2015_12 FBgn0052363 tRNA:CR32363 transfer RNA:CR32363 http://flybase.net/reports/FBgn0052363.html "FBgn0011907, FBgn0060161" tRNA_gene "0033420=CUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR32363, tRNA[Leu][[2]], tRNA:leu2:66B, chr3L.trna39-LeuCAG, tRNA:L:CAG:AE002602-a, tRNA:L2:66B, transfer RNA:leu2:66B, AE002602.trna5-LeuCAG" CR32363 16-Dec-15 2015_12 FBgn0044107 E(rst)C389 E(rst)C389 http://flybase.net/reports/FBgn0044107.html gene 0001745=compound eye morphogenesis C389 16-Dec-15 2015_12 viable eye FBgn0034512 CG18067 http://flybase.net/reports/FBgn0034512.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CT40493 CG18067 16-Dec-15 2015_12 viable FBgn0086610 CG33342 HDC15381 http://flybase.net/reports/FBgn0086610.html "FBgn0082651, FBgn0053342" protein_coding_gene "CG33342, unnamed, HDC15381, mdcds_42691, BP1089" IPR006631=Protein of unknown function DM4/12 CG33342 16-Dec-15 2015_12 FBgn0263852 l(2)k12914 lethal (2) k12914 http://flybase.net/reports/FBgn0263852.html "FBgn0021896, FBgn0032035, FBgn0063049" protein_coding_gene "0004579=dolichyl-diphosphooligosaccharide-protein glycotransferase activity, 0004576=oligosaccharyl transferase activity" 0043066=negative regulation of apoptotic process "0016021=integral component of membrane, 0005886=plasma membrane, 0008250=oligosaccharyltransferase complex, 0012505=endomembrane system" "CG13393, BcDNA:RE23864, OST" IPR003038=DAD/Ost2 CG13393 16-Dec-15 2015_12 ENSDARG00000059791(dad1) YOR103C(OST2) WBGene00000896(dad-1) ENSXETG00000026483(dad1) ENSMUSG00000022174(Dad1) ENSG00000129562(DAD1) FBgn0261861 CG42790 http://flybase.net/reports/FBgn0261861.html protein_coding_gene lincRNA.863 CG42790 16-Dec-15 2015_12 FBgn0265348 CR44302 http://flybase.net/reports/FBgn0265348.html non_protein_coding_gene CR44302 16-Dec-15 2015_12 FBgn0265592 CR44419 http://flybase.net/reports/FBgn0265592.html non_protein_coding_gene CR44419 16-Dec-15 2015_12 FBgn0266526 CG45093 http://flybase.net/reports/FBgn0266526.html protein_coding_gene CG45093 16-Dec-15 2015_12 FBgn0262449 mir-2b-2 mir-2b-2 stem loop http://flybase.net/reports/FBgn0262449.html "FBgn0046823, FBgn0262309" miRNA_gene "0046716=muscle cell cellular homeostasis, 0060548=negative regulation of cell death, 0045947=negative regulation of translational initiation" "dme-miR-2b, miR-2b, dme-mir-2b-2, mir-2b-2, miR-2, CR43016, 2b-1/2, CR32964, miR-2b-2, miR2, miR2b, 2b-2, mir-2b" CR43016 16-Dec-15 2015_12 embryonic stage -- adult stage "visible,lethal" wing FBgn0267086 CR45530 http://flybase.net/reports/FBgn0267086.html non_protein_coding_gene CR45530 16-Dec-15 2015_12 FBgn0035736 Cpr65Eb Cuticular protein 65Eb http://flybase.net/reports/FBgn0035736.html FBgn0063039 protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "BcDNA:RE28679, CG8638, DmelCpr65Eb" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8638 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0014317 l(3)ry125b lethal (3) ry125b http://flybase.net/reports/FBgn0014317.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003581 Su(ss) Suppressor of spineless http://flybase.net/reports/FBgn0003581.html gene 16-Dec-15 2015_12 "lethal,recessive" "posterior scutellar bristle,macrochaeta" FBgn0011663 mrr myosin rod-related http://flybase.net/reports/FBgn0011663.html gene 16-Dec-15 2015_12 FBgn0031533 CG2772 http://flybase.net/reports/FBgn0031533.html FBgn0063009 protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process BcDNA:RE45077 "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG2772 16-Dec-15 2015_12 YKL140W(TGL1) viable FBgn0039807 CG15546 http://flybase.net/reports/FBgn0039807.html protein_coding_gene CG15546 16-Dec-15 2015_12 FBgn0267282 CR45718 http://flybase.net/reports/FBgn0267282.html non_protein_coding_gene CR45718 16-Dec-15 2015_12 FBgn0052484 Sk2 Sphingosine kinase 2 http://flybase.net/reports/FBgn0052484.html FBgn0035391 protein_coding_gene "0004143=diacylglycerol kinase activity, 0017050=D-erythro-sphingosine kinase activity" "0016310=phosphorylation, 0018991=oviposition, 0006665=sphingolipid metabolic process, 0007629=flight behavior" "0005737=cytoplasm, 0005765=lysosomal membrane" "sphingosine kinase, Sphingosine kinase II, sphingosine kinase 2, sk2, Sphk2, CG2159, SK2, CG32484" "IPR001206=Diacylglycerol kinase, catalytic domain, IPR016064=NAD kinase/diacylglycerol kinase-like domain" CG32484 16-Dec-15 2015_12 ENSDARG00000059987 "YOR171C(LCB4),YLR260W(LCB5)" WBGene00007918(sphk-1) "ENSXETG00000003163(SPHK2),ENSXETG00000019540(sphk1)" ENSMUSG00000057342(Sphk2) ENSG00000063176(SPHK2) "viable,female sterile,recessive,flight defective,fertile" "eye,photoreceptor cell,ommatidium,rhabdomereGMR.PF,heat sensitive,rhabdomere | heat sensitiveGMR.PF, GAL80ts.ë±Tub84B" FBgn0266729 CR45202 http://flybase.net/reports/FBgn0266729.html non_protein_coding_gene CR45202 16-Dec-15 2015_12 FBgn0032847 Taf13 TBP-associated factor 13 http://flybase.net/reports/FBgn0032847.html protein_coding_gene "0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0046982=protein heterodimerization activity" 0006367=transcription initiation from RNA polymerase II promoter 0005669=transcription factor TFIID complex "TAF, TFIID, TAF13, TBP-associated factor 18kD, TBP-associated factor, CG10756, TAF[[II]]18, TAF[[II]], dTAF[[II]]18, TAF18, Taf18, 38B.15" "IPR003195=Transcription initiation factor IID, 18kDa subunit, IPR009072=Histone-fold" CG10756 16-Dec-15 2015_12 ENSDARG00000070834(taf13) YML098W(TAF13) WBGene00006397(taf-13) ENSXETG00000020838(taf13) ENSMUSG00000048100(Taf13) "ENSG00000197780(TAF13),ENSG00000215719" "viable,visible" "chaeta,supernumerary" FBgn0052545 CG32545 http://flybase.net/reports/FBgn0052545.html protein_coding_gene 16-Dec-15 2015_12 FBgn0023221 E(lz)15 E(lz)15 http://flybase.net/reports/FBgn0023221.html gene 16-Dec-15 2015_12 wild-type FBgn0065827 l(2)SH0357 lethal (2) SH0357 http://flybase.net/reports/FBgn0065827.html gene l(2)SH2 0357 16-Dec-15 2015_12 "lethal,recessive" FBgn0084271 l(3)AS69 lethal (3) AS69 http://flybase.net/reports/FBgn0084271.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031277 CG13947 http://flybase.net/reports/FBgn0031277.html protein_coding_gene CG13947 16-Dec-15 2015_12 FBgn0060344 l(3)S143609 lethal (3) S143609 http://flybase.net/reports/FBgn0060344.html gene 1436/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0021992 l(2)k09610 lethal (2) k09610 http://flybase.net/reports/FBgn0021992.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003614 Su(var)2-12 Suppressor of variegation 2-12 http://flybase.net/reports/FBgn0003614.html gene Su-var(2)12 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0039225 Ets96B Ets96B http://flybase.net/reports/FBgn0039225.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "ets96B, Ets, CG6892" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain" CG6892 16-Dec-15 2015_12 "ENSMUSG00000017724(Etv4),ENSMUSG00000004151(Etv1),ENSMUSG00000047643(Gm5454),ENSMUSG00000013089(Etv5),ENSMUSG00000044690" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16127 IK 1.561532078 -0.398148557 -0.083853677 -0.00114459 1.684860398 0.798561845 FBgn0262100 CG42853 http://flybase.net/reports/FBgn0262100.html protein_coding_gene IPR003388=Reticulon CG42853 16-Dec-15 2015_12 FBgn0044004 Su(rst)C195 Su(rst)C195 http://flybase.net/reports/FBgn0044004.html gene 0001745=compound eye morphogenesis C195 16-Dec-15 2015_12 viable eye FBgn0266685 CR45175 http://flybase.net/reports/FBgn0266685.html non_protein_coding_gene CR45175 16-Dec-15 2015_12 FBgn0061403 CG32738 http://flybase.net/reports/FBgn0061403.html FBgn0052738 protein_coding_gene BcDNA:RE36972 16-Dec-15 2015_12 FBgn0004985 bow bow wings http://flybase.net/reports/FBgn0004985.html gene 16-Dec-15 2015_12 "visible,recessive" wing FBgn0045036 stuk stuk http://flybase.net/reports/FBgn0045036.html gene stuck in place 16-Dec-15 2015_12 FBgn0005779 PpD6 Protein phosphatase D6 http://flybase.net/reports/FBgn0005779.html FBgn0031503 protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation "protein phosphatase from PCR fragment D6, PP1, D6, PP1-like, CG8822" "IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like" CG8822 16-Dec-15 2015_12 "viable,fertile,lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0036789 AstC-R2 Allatostatin C receptor 2 http://flybase.net/reports/FBgn0036789.html "FBgn0046583, FBgn0046584" protein_coding_gene "0004994=somatostatin receptor activity, 0004930=G-protein coupled receptor activity, 0008261=allatostatin receptor activity, 0008188=neuropeptide receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "ASTC-R2, anon-WO0170980.154, AlCR-2, anon-WO0170980.155, Allatostatin C receptor 2, CG13702, AlCR2, ASC-receptor, Somatostatin receptor, lincRNA.610, Drosophila allatostatin C receptor 2, Drostar2, allatostatin C receptor 2, allatostatin C receptor2" "IPR000586=Somatostatin receptor family, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG13702 16-Dec-15 2015_12 "ENSDARG00000028785,ENSDARG00000067925(LOC557645),ENSDARG00000003049(sstr1),ENSDARG00000059090(LOC100333578),ENSDARG00000069806(LOC560530)" WBGene00020086(R106.2) "ENSXETG00000005731(SSTR5),ENSXETG00000009978(SSTR2),ENSXETG00000016039(SSTR3)" "ENSMUSG00000047904(Sstr2),ENSMUSG00000050824(Sstr5),ENSMUSG00000035431(Sstr1),ENSMUSG00000044933(Sstr3),ENSMUSG00000037014(Sstr4)" "ENSG00000180616(SSTR2),ENSG00000162009(SSTR5),ENSG00000183473(SSTR3),ENSG00000139874(SSTR1),ENSG00000132671(SSTR4)" " adult stage , larval stage " " lamina & glial cell

, pars intercerebralis | restricted

, larval central nervous system | restricted

, monopolar laminar cell

" "viable,fertile" FBgn0010222 Nmdmc NAD-dependent methylenetetrahydrofolate dehydrogenase http://flybase.net/reports/FBgn0010222.html FBgn0037658 protein_coding_gene "0004329=formate-tetrahydrofolate ligase activity, 0000287=magnesium ion binding, 0004477=methenyltetrahydrofolate cyclohydrolase activity, 0004487=methylenetetrahydrofolate dehydrogenase (NAD+) activity, 0004488=methylenetetrahydrofolate dehydrogenase (NADP+) activity" "0055114=oxidation-reduction process, 0009256=10-formyltetrahydrofolate metabolic process, 0009396=folic acid-containing compound biosynthetic process, 0006730=one-carbon metabolic process, 0005975=carbohydrate metabolic process" "0005739=mitochondrion, 0005829=cytosol" "unnamed, NAD dependent methylenetetrahydrofolate dehydrogenase, DNMDMC, dNMDMC, Dnmdmc, nmdmc, Mthfd2, CG18466, 151767_at" "IPR020867=Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site, IPR000672=Tetrahydrofolate dehydrogenase/cyclohydrolase, IPR016040=NAD(P)-binding domain, IPR020631=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, IPR020630=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain" CG18466 16-Dec-15 2015_12 "ENSDARG00000026666(LOC100331625),ENSDARG00000054199(mthfd2l)" YKR080W(MTD1) WBGene00000929(dao-3) "ENSXETG00000012094(),ENSXETG00000006377(MTHFD2L)" "ENSMUSG00000005667(Mthfd2),ENSMUSG00000029376(Mthfd2l)" "ENSG00000065911(MTHFD2),ENSG00000163738(MTHFD2L)" embryonic stage -- adult stage "viable,fertile" FBgn0263206 CG43376 http://flybase.net/reports/FBgn0263206.html protein_coding_gene CG43376 16-Dec-15 2015_12 FBgn0023105 anon-23Aa anon-23Aa http://flybase.net/reports/FBgn0023105.html gene transcript B 16-Dec-15 2015_12 FBgn0266630 CR45137 http://flybase.net/reports/FBgn0266630.html non_protein_coding_gene CR45137 16-Dec-15 2015_12 FBgn0010166 pseudoscute pseudoscute http://flybase.net/reports/FBgn0010166.html gene psc 16-Dec-15 2015_12 FBgn0022192 l(2)k05104 lethal (2) k05104 http://flybase.net/reports/FBgn0022192.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262616 CR43142 http://flybase.net/reports/FBgn0262616.html pseudogene_attribute CR43142 16-Dec-15 2015_12 FBgn0028110 l(3)S068609 lethal (3) S068609 http://flybase.net/reports/FBgn0028110.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034232 CG4866 http://flybase.net/reports/FBgn0034232.html protein_coding_gene "0003735=structural constituent of ribosome, 0019843=rRNA binding" "0006412=translation, 0009267=cellular response to starvation" 0005761=mitochondrial ribosome mRpS4 "IPR002942=RNA-binding S4 domain, IPR022801=Ribosomal protein S4/S9, IPR001912=Ribosomal protein S4/S9, N-terminal" CG4866 16-Dec-15 2015_12 "ENSDARG00000069287(imp3),ENSDARG00000034233" YHR148W(IMP3) WBGene00016740(C48B6.2) ENSMUSG00000032288(Imp3) ENSG00000177971 "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0028689 Rpn6 Regulatory particle non-ATPase 6 http://flybase.net/reports/FBgn0028689.html "FBgn0022278, FBgn0027867" protein_coding_gene 0005515=protein binding 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0005838=proteasome regulatory particle, 0005875=microtubule associated complex, 0000502=proteasome complex, 0008541=proteasome regulatory particle, lid subcomplex" "Proteasome p44.5 subunit, BcDNA:LD18931, rpn6, CG10149, dPSMD11, S9, CG5289, p42B, l(2)k00103, Pros44.5, BcDNA.LD18931" "IPR013143=PCI/PINT associated module, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR011990=Tetratricopeptide-like helical domain, IPR000717=Proteasome component (PCI) domain" CG10149 16-Dec-15 2015_12 "ENSDARG00000005134(psmd11b),ENSDARG00000060150(im:7148232)" YDL097C(RPN6) WBGene00004462(rpn-6) ENSMUSG00000017428(Psmd11) ENSG00000108671(PSMD11) "lethal,recessive,neuroanatomy defective,somatic clone,decreased cell number,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,cell lethalcell lethal" "mushroom body gamma-lobe,somatic clone,neuroblast,adult mushroom body" DRSC07541 IEK -2.917126882 -2.849851167 -1.833524703 -3.83491377 -1.036150642 -2.002357269 FBgn0005260 l(3)SG80 lethal (3) SG80 http://flybase.net/reports/FBgn0005260.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267500 2SrRNA:CR45840 2S ribosomal RNA:CR45840 http://flybase.net/reports/FBgn0267500.html rRNA_gene CR45840 CR45840 16-Dec-15 2015_12 FBgn0002417 l(3)DTS4 lethal (3) DTS4 http://flybase.net/reports/FBgn0002417.html gene DTS-4 16-Dec-15 2015_12 "lethal,dominant,heat sensitive" FBgn0260224 CG42498 http://flybase.net/reports/FBgn0260224.html protein_coding_gene Dromel_CG14550_FBtr0084974_uORF IPR015419=CTAG/Pcc1 family CG42498 16-Dec-15 2015_12 "ENSG00000196976(LAGE3),ENSG00000184033(CTAG1B),ENSG00000183678(CTAG1A)" FBgn0262772 Su(E1)-F http://flybase.net/reports/FBgn0262772.html gene 16-Dec-15 2015_12 FBgn0004856 Bx42 Bx42 http://flybase.net/reports/FBgn0004856.html protein_coding_gene 0005515=protein binding "0000398=mRNA splicing, via spliceosome, 0035214=eye-antennal disc development, 0001700=embryonic development via the syncytial blastoderm" "0000974=Prp19 complex, 0071013=catalytic step 2 spliceosome, 0000790=nuclear chromatin, 0071011=precatalytic spliceosome, 0005634=nucleus" "bx42, Ski-interacting protein, CG8264, BX42, SKIP, Skip" "IPR017862=SKI-interacting protein, SKIP, IPR004015=SKI-interacting protein SKIP, SNW domain" CG8264 16-Dec-15 2015_12 ENSDARG00000036522(LOC100329938) YAL032C(PRP45) WBGene00004806(skp-1) ENSXETG00000011087(skiip) ENSMUSG00000021039(Snw1) ENSG00000100603(SNW1) embryonic stage

ubiquitous " larval stage | third instar , adult stage && oogenesis stage , embryonic stage | cellular blastoderm , embryonic stage " " larval salivary gland

, follicle cell

, nurse cell

" "viable,fertile,neuroanatomy defective,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,salivary gland,eye,antenna,ectopic,head | P-stage,gnathal segment,mouthpart,anterior scutellar bristle,posterior scutellar bristle,anterior crossvein,wing vein L3,leg,1st posterior cell,wing vein" DRSC17743 EK -1.15987685 -0.345352015 -3.921648019 -4.411487858 -3.03720369 -0.587458187 FBgn0033286 CG2127 http://flybase.net/reports/FBgn0033286.html "FBgn0044619, FBgn0045245" protein_coding_gene "anon-WO0140519.25, bs19a07.y1, NEST:bs19a07" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG2127 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0039424 ppk15 pickpocket 15 http://flybase.net/reports/FBgn0039424.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "CG14239, pickpocket 15, ppk15" "IPR001873=Na+ channel, amiloride-sensitive" CG14239 16-Dec-15 2015_12 viable FBgn0032512 CG9305 http://flybase.net/reports/FBgn0032512.html protein_coding_gene "0001026=TFIIIB-type transcription factor activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006359=regulation of transcription from RNA polymerase III promoter, 0022008=neurogenesis, 0048812=neuron projection morphogenesis" "0000126=transcription factor TFIIIB complex, 0005634=nucleus" Bdp1 "IPR030701=Transcription factor TFIIIB component B'', IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like" CG9305 16-Dec-15 2015_12 ENSDARG00000053091 YNL039W(BDP1) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC03192 K 0.398334979 -0.678673429 0.589984839 -0.972481727 -1.701147062 -0.974367294 FBgn0011738 wwy wrong way http://flybase.net/reports/FBgn0011738.html gene 0007409=axonogenesis 16-Dec-15 2015_12 "chordotonal organ & axon | lateral,commissure,longitudinal connective" FBgn0039702 Vps16B Vacuolar protein sorting 16B http://flybase.net/reports/FBgn0039702.html protein_coding_gene 0005515=protein binding "0016197=endosomal transport, 0090382=phagosome maturation, 0035542=regulation of SNARE complex assembly, 0090385=phagosome-lysosome fusion, 0006955=immune response" "0005737=cytoplasm, 0033263=CORVET complex, 0030897=HOPS complex" "fob, full-of-bacteria, dVps16B, CG18112, Vps16b, Vps16B" IPR019177=Golgin subfamily A member 5 CG18112 16-Dec-15 2015_12 ENSDARG00000030976(vipar) ENSXETG00000011084(VIPAR) ENSMUSG00000021038(Vipar) ENSG00000151445(VIPAR) "visible,partially lethal - majority die,some die during pupal stage,viable,fertile,immune response defective" "trichogen cell,hemocyte" FBgn0000696 fltB flight defective B http://flybase.net/reports/FBgn0000696.html gene 16-Dec-15 2015_12 flight defective FBgn0017484 Su(var)324 Suppressor of variegation 324 http://flybase.net/reports/FBgn0017484.html gene 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant" FBgn0261863 lnr lingerer on 2L http://flybase.net/reports/FBgn0261863.html gene 0035177=larval foraging behavior lingerer 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263567 mir-4915 mir-4915 stem loop http://flybase.net/reports/FBgn0263567.html miRNA_gene "CR43552, dme-mir-4915" CR43552 16-Dec-15 2015_12 FBgn0010282 TfIIFë± Transcription factor IIFë± http://flybase.net/reports/FBgn0010282.html FBgn0010281 protein_coding_gene "0003824=catalytic activity, 0003677=DNA binding, 0001096=TFIIF-class transcription factor binding" "0022008=neurogenesis, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0060261=positive regulation of transcription initiation from RNA polymerase II promoter" "0005634=nucleus, 0005674=transcription factor TFIIF complex" "large subunit of transcription factor 5, 154355_at, factor 5a, TFIIFa, TfIIFalpha, TFIIFalpha, F5a, TFIIF, TfIIF, CG10281, TFIIF large subunit, DmTFIIF, TFIIF-L, factor 5" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR011039=Transcription Factor IIF, Rap30/Rap74, interaction, IPR008851=Transcription initiation factor IIF, alpha subunit" CG10281 16-Dec-15 2015_12 ENSDARG00000032129(gtf2f1) WBGene00015296(C01F1.1) ENSXETG00000005579(GTF2F1) ENSMUSG00000002658(Gtf2f1) ENSG00000125651(GTF2F1) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC12608 IK 0.717110214 3.410797271 -0.905632142 0.80246442 1.579373929 0.604596943 FBgn0259637 B0625 http://flybase.net/reports/FBgn0259637.html gene 16-Dec-15 2015_12 visible wing vein L3 FBgn0265491 BG01478 http://flybase.net/reports/FBgn0265491.html gene 16-Dec-15 2015_12 FBgn0263514 mir-4966-1 mir-4966-1 stem loop http://flybase.net/reports/FBgn0263514.html miRNA_gene "dme-mir-4966-1, mir-4966 stem loop, dme-mir-4966, mir-4966, chou39-1, CR43499" CR43499 16-Dec-15 2015_12 viable FBgn0040183 l(1)G0257 lethal (1) G0257 http://flybase.net/reports/FBgn0040183.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039591 CG9988 http://flybase.net/reports/FBgn0039591.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process gi23172514 "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR004245=Protein of unknown function DUF229, IPR017850=Alkaline-phosphatase-like, core domain" CG9988 16-Dec-15 2015_12 viable FBgn0065213 l(2)SH2258 lethal (2) SH2258 http://flybase.net/reports/FBgn0065213.html gene l(2)SH2 2258 16-Dec-15 2015_12 "lethal,recessive" FBgn0004496 fs(1)201 female sterile (1) 201 http://flybase.net/reports/FBgn0004496.html gene 16-Dec-15 2015_12 FBgn0004432 Cyp1 Cyclophilin 1 http://flybase.net/reports/FBgn0004432.html FBgn0047257 protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding" "0005875=microtubule associated complex, 0008024=positive transcription elongation factor complex b, 0019908=nuclear cyclin-dependent protein kinase holoenzyme complex, 0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" "Cyp-1, CG9916, cyp-1, BcDNA:GM09255, cyclophilin1, cyp1, CyP-1, Peptidylprolyl isomerase F, Peptidyl-prolyl cis-trans isomerase, Cpy1" "IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG9916 16-Dec-15 2015_12 ENSDARG00000009212(ppia) YDR155C(CPR1) "WBGene00000879(cyn-3),WBGene00000883(cyn-7),WBGene00000878(cyn-2),WBGene00000877(cyn-1)" ENSXETG00000018981(ppia) ENSMUSG00000021868(Ppif) ENSG00000108179(PPIF) larval stage | third instar dorsal mesothoracic disc

"lethal,recessive,viable,visible" trichogen cell FBgn0265589 CR44416 http://flybase.net/reports/FBgn0265589.html non_protein_coding_gene CR44416 16-Dec-15 2015_12 FBgn0046330 l(2)38ABb lethal (2) 38ABb http://flybase.net/reports/FBgn0046330.html gene lethal in 38A/B 16-Dec-15 2015_12 FBgn0035953 CG5087 http://flybase.net/reports/FBgn0035953.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination" "0005737=cytoplasm, 0005634=nucleus" NM_140022.1 "IPR000048=IQ motif, EF-hand binding site, IPR000569=HECT domain" CG5087 16-Dec-15 2015_12 ENSDARG00000061960(LOC556864) WBGene00003898(oxi-1) ENSXETG00000018590(UBE3B) ENSMUSG00000029577(Ube3b) ENSG00000151148(UBE3B) viable FBgn0036443 CG13471 http://flybase.net/reports/FBgn0036443.html protein_coding_gene CG13471 16-Dec-15 2015_12 viable FBgn0040821 CG14148 http://flybase.net/reports/FBgn0040821.html protein_coding_gene 16-Dec-15 2015_12 FBgn0259214 PMCA plasma membrane calcium ATPase http://flybase.net/reports/FBgn0259214.html "FBgn0025704, FBgn0025688, FBgn0039903, FBgn0054036, FBgn0082885" protein_coding_gene "0046872=metal ion binding, 0005524=ATP binding, 0005388=calcium-transporting ATPase activity" "0070588=calcium ion transmembrane transport, 0006874=cellular calcium ion homeostasis" "0005886=plasma membrane, 0016021=integral component of membrane" "BEST:CK, CG2165, CK02288, plasma membrane Ca2+ ATPase, plasma membrane Ca[2+] ATPase, BP1021, BEST:CK02288, CG42314, BEST:CK01140, unnamed, CG34036" "IPR023214=HAD-like domain, IPR006068=Cation-transporting P-type ATPase, C-terminal, IPR004014=Cation-transporting P-type ATPase, N-terminal, IPR030319=Plasma membrane calcium-transporting ATPase 4, IPR023298=P-type ATPase, transmembrane domain, IPR001757=P-type ATPase, IPR006408=P-type ATPase, subfamily IIB, IPR023299=P-type ATPase, cytoplasmic domain N, IPR008250=P-type ATPase, A domain, IPR022141=Plasma membrane calcium transporting P-type ATPase, C-terminal, IPR018303=P-type ATPase, phosphorylation site" CG42314 16-Dec-15 2015_12 "ENSDARG00000012684(atp2b1a),ENSDARG00000007788(atp2b1b),ENSDARG00000063433,ENSDARG00000043474(atp2b3a),ENSDARG00000044902,ENSDARG00000023445(atp2b3b)" YGL006W(PMC1) WBGene00003153(mca-3) ENSXETG00000003618(ATP2B2) "ENSMUSG00000019943(Atp2b1),ENSMUSG00000030302(Atp2b2),ENSMUSG00000031376(Atp2b3),ENSMUSG00000026463(Atp2b4)" "ENSG00000067842(ATP2B3),ENSG00000157087(ATP2B2),ENSG00000070961(ATP2B1),ENSG00000058668(ATP2B4)" FBgn0030342 CG10347 http://flybase.net/reports/FBgn0030342.html protein_coding_gene 0005515=protein binding 0005654=nucleoplasm "HSP20, Q9VYT5" "IPR007052=CS domain, IPR008978=HSP20-like chaperone" CG10347 16-Dec-15 2015_12 ENSDARG00000036158(nudcd1) WBGene00016654(C44E4.5) ENSXETG00000010497(nudcd1) ENSMUSG00000038736(Nudcd1) ENSG00000120526(NUDCD1) viable FBgn0000602 E(var)301 Enhancer of variegation 301 http://flybase.net/reports/FBgn0000602.html gene En(var)301 16-Dec-15 2015_12 "viable,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0266509 s-454 http://flybase.net/reports/FBgn0266509.html gene 16-Dec-15 2015_12 FBgn0066072 Su(var)2-14 Su(var)2-14 http://flybase.net/reports/FBgn0066072.html gene 16-Dec-15 2015_12 FBgn0086265 psd palisade http://flybase.net/reports/FBgn0086265.html "FBgn0000646, FBgn0031755, FBgn0064929" protein_coding_gene "0032529=follicle cell microvillus organization, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "0060388=vitelline envelope, 0042600=chorion" "Follicle cell protein 26Aa, Palisade, BcDNA:GM32356, CG9050, Fcp26Aa, TU-1" CG9050 16-Dec-15 2015_12 adult stage && oogenesis stage | stage S8-10B oocyte | posterior

"female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "microvillus & follicle cell,vitelline membrane,microvillus & follicle celldm-PG45,cortical actin cytoskeleton & oocytedm-PG45" FBgn0015541 sda slamdance http://flybase.net/reports/FBgn0015541.html FBgn0027573 protein_coding_gene "0008270=zinc ion binding, 0004177=aminopeptidase activity, 0008237=metallopeptidase activity" "0007638=mechanosensory behavior, 0042391=regulation of membrane potential, 0009612=response to mechanical stimulus, 0006508=proteolysis, 2001020=regulation of response to DNA damage stimulus" "Sda, CG5518, BcDNA:GH07466" "IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571=ERAP1-like C-terminal domain" CG5518 16-Dec-15 2015_12 "viable,fertile,neurophysiology defective,bang sensitive,lethal,recessive,dominant,paralytic,drug conditional,semidominant,body color defective,planar polarity defective,partially lethal - majority die,some die during pupal stage" "aCC neuron,RP2 motor neuron,mesothoracic tergum" FBgn0019704 l(2)42Bd lethal (2) 42Bd http://flybase.net/reports/FBgn0019704.html gene "4LL1, l(2)4LL1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267614 CR45952 http://flybase.net/reports/FBgn0267614.html non_protein_coding_gene CR45952 16-Dec-15 2015_12 FBgn0034788 CG13532 http://flybase.net/reports/FBgn0034788.html protein_coding_gene 0005576=extracellular region CT32907 "IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG13532 16-Dec-15 2015_12 viable FBgn0024907 anon-99Fb anon-99Fb http://flybase.net/reports/FBgn0024907.html gene K8 16-Dec-15 2015_12 FBgn0027972 l(3)S142603b lethal (3) S142603b http://flybase.net/reports/FBgn0027972.html gene "1426/03, l(3)S142603" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0061479 sorc sorciere http://flybase.net/reports/FBgn0061479.html gene "0008359=regulation of bicoid mRNA localization, 0007303=cytoplasmic transport, nurse cell to oocyte, 0045450=bicoid mRNA localization" 16-Dec-15 2015_12 female sterile "egg,egg chamber,germline clone" FBgn0031573 CG3407 http://flybase.net/reports/FBgn0031573.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" cg3407 "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG3407 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0000337 cn cinnabar http://flybase.net/reports/FBgn0000337.html protein_coding_gene 0004502=kynurenine 3-monooxygenase activity "0019674=NAD metabolic process, 0006569=tryptophan catabolic process, 0006727=ommochrome biosynthetic process, 0006726=eye pigment biosynthetic process, 0048072=compound eye pigmentation, 0019805=quinolinate biosynthetic process, 0070189=kynurenine metabolic process, 1901216=positive regulation of neuron death" 0005741=mitochondrial outer membrane "CG1555, Dmel\cn, KMO" "IPR002938=FAD-binding domain, IPR027545=Kynurenine 3-monooxygenase" CG1555 16-Dec-15 2015_12 ENSDARG00000009160(kmo) YBL098W(BNA4) WBGene00011089(R07B7.5) ENSXETG00000016227(Q6DIZ8_XENTR) ENSMUSG00000039783(Kmo) ENSG00000117009(KMO) larval stage--pupal stage "eye color defective,recessive,visible,male sterile,female sterile,viable" "pigment cell,ocellus,ocellus pigment granule,Malpighian tubule" FBgn0030311 CG11699 http://flybase.net/reports/FBgn0030311.html protein_coding_gene IPR009792=Protein of unknown function DUF1358 CG11699 16-Dec-15 2015_12 ENSDARG00000037070(si:dkey-60a16.5) ENSXETG00000025083(C6orf35) ENSMUSG00000004945(5730437N04Rik) "ENSG00000215712(C6orf35),ENSG00000122339" "viable,fertile,chemical sensitive,behavior defective" DRSC19419 K 0.631602312 0.51563869 -0.28271621 0.620936729 -1.95884653 -0.697266057 FBgn0054016 CG34016 http://flybase.net/reports/FBgn0054016.html FBgn0082836 protein_coding_gene "unnamed, BP1070" 16-Dec-15 2015_12 FBgn0051676 CG31676 http://flybase.net/reports/FBgn0051676.html "FBgn0032893, FBgn0041001, FBgn0061379" protein_coding_gene "BcDNA:RH34376, CG14403, CG14404" CG31676 16-Dec-15 2015_12 "WBGene00019663(K11H12.7),WBGene00019662(K11H12.6)" "viable,fertile" FBgn0036519 CG7650 http://flybase.net/reports/FBgn0036519.html FBgn0063705 protein_coding_gene 0007602=phototransduction BcDNA:AT27057 "IPR024253=Phosducin, thioredoxin-like domain, IPR012336=Thioredoxin-like fold, IPR001200=Phosducin, IPR023196=Phosducin N-terminal domain" CG7650 16-Dec-15 2015_12 ENSDARG00000009480(zgc:73264) WBGene00003142(mau-8) ENSXETG00000016335(PDCL) ENSMUSG00000009030(Pdcl) ENSG00000136940(PDCL) "viable,visible" mesothoracic tergum FBgn0032644 CG5131 http://flybase.net/reports/FBgn0032644.html protein_coding_gene 0004222=metalloendopeptidase activity "IPR019165=Peptidase M76, ATP23" CG5131 16-Dec-15 2015_12 ENSDARG00000063686(zgc:162885) YNR020C(ATP23) ENSXETG00000014677(TEgg079g08.1) ENSG00000166896(XRCC6BP1) "viable,fertile" FBgn0013698 mt:tRNA:L:CUN mitochondrial leucine CUN tRNA http://flybase.net/reports/FBgn0013698.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "leucine[CUN] tRNA, mtdbD00006312, CR34093" CR34093 16-Dec-15 2015_12 FBgn0263212 CR43382 http://flybase.net/reports/FBgn0263212.html pseudogene_attribute CR43382 16-Dec-15 2015_12 FBgn0051922 CG31922 http://flybase.net/reports/FBgn0051922.html FBgn0044376 protein_coding_gene 0008270=zinc ion binding "0000398=mRNA splicing, via spliceosome" "0030532=small nuclear ribonucleoprotein complex, 0005689=U12-type spliceosomal complex" "anon-AE003587.1, 20K" "IPR013085=Zinc finger, U1-C type" CG31922 16-Dec-15 2015_12 ENSMUSG00000009076(Zmat5) ENSG00000100319(ZMAT5) viable FBgn0036218 Sprn Spermitin http://flybase.net/reports/FBgn0036218.html protein_coding_gene 0046907=intracellular transport 0016006=Nebenkern "sprn, CG14128" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000156=Ran binding domain" CG14128 16-Dec-15 2015_12 viable FBgn0267266 CR45702 http://flybase.net/reports/FBgn0267266.html non_protein_coding_gene CR45702 16-Dec-15 2015_12 FBgn0017632 Eig12E Eig12E http://flybase.net/reports/FBgn0017632.html gene "Eig12, Ecdysone-induced gene 12E" 16-Dec-15 2015_12 FBgn0060372 l(3)S136808b lethal (3) S136808b http://flybase.net/reports/FBgn0060372.html gene 1368/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0034468 Obp56a Odorant-binding protein 56a http://flybase.net/reports/FBgn0034468.html FBgn0063005 protein_coding_gene 0005549=odorant binding "0007606=sensory perception of chemical stimulus, 0019236=response to pheromone, 0042048=olfactory behavior, 0007608=sensory perception of smell" 0005576=extracellular region "obp56a, BcDNA:RE46170, CG11797, DmelObp56a, 56a" IPR006170=Pheromone/general odorant binding protein CG11797 16-Dec-15 2015_12 viable DRSC06085 E -0.245131351 1.157026317 -0.069054714 1.544745426 -0.91077311 -0.118708152 FBgn0003704 thvd thick vein delta http://flybase.net/reports/FBgn0003704.html gene "delta vein, dtv" 16-Dec-15 2015_12 "male fertile,viable,male,reduced,visible,recessive" "wing,wing vein,wing vein L2,anal plate,genital arch,genitalia" FBgn0002194 l(3)63Be lethal (3) 63Be http://flybase.net/reports/FBgn0002194.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0020837 l(2)F9 Florida 9 http://flybase.net/reports/FBgn0020837.html gene l(2)Fla.'9 16-Dec-15 2015_12 partially lethal - majority die FBgn0003291 Rst(3)ns Resistant to nicotine http://flybase.net/reports/FBgn0003291.html gene Resistance (3) nicotine sulfate 16-Dec-15 2015_12 chemical resistant FBgn0003686 tfd two-faced http://flybase.net/reports/FBgn0003686.html gene 16-Dec-15 2015_12 "eye,head bristle,adult cuticle,ocellus,antenna,labellum,eye-antennal disc" FBgn0024633 l(2)k14039 lethal (2) k14039 http://flybase.net/reports/FBgn0024633.html gene 140/39 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0085343 Sws1 SWIM domain containing Srs2 interacting protein 1 http://flybase.net/reports/FBgn0085343.html protein_coding_gene "Dromel_CG3240_FBtr0077747_rad1_uORF, dmSws1, CG34314" CG34314 16-Dec-15 2015_12 FBgn0030504 CG2691 http://flybase.net/reports/FBgn0030504.html protein_coding_gene 0048812=neuron projection morphogenesis 0005634=nucleus "IPR016024=Armadillo-type fold, IPR012978=Uncharacterised domain NUC173" CG2691 16-Dec-15 2015_12 ENSDARG00000022410(rrp12) YPL012W(RRP12) WBGene00021595(Y46E12BL.2) ENSXETG00000003430(Q6GL70_XENTR) ENSMUSG00000035049(Rrp12) ENSG00000052749(RRP12) "viable,fertile" FBgn0002136 l(2)K225 lethal (2) K225 http://flybase.net/reports/FBgn0002136.html gene 16-Dec-15 2015_12 lethal FBgn0259704 Nsun5 Nop2/Sun-like domain containing protein 5 http://flybase.net/reports/FBgn0259704.html "FBgn0038684, FBan0005558, FBgn0036884" protein_coding_gene 0008168=methyltransferase activity "0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response" "CG5558, dNsun5, CG42358" "IPR001678=SAM-dependent methyltransferase RsmB/NOP2-type, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR023267=RNA (C5-cytosine) methyltransferase" CG42358 16-Dec-15 2015_12 ENSDARG00000043209(zgc:77183) WBGene00013151(Y53F4B.4) ENSXETG00000010332() ENSMUSG00000000916(Nsun5) "ENSG00000130305(NSUN5),ENSG00000106133" viable FBgn0033238 azot ahuizotl http://flybase.net/reports/FBgn0033238.html "FBgn0047348, FBgn0064999" protein_coding_gene 0005509=calcium ion binding 0043065=positive regulation of apoptotic process "CG11165, BcDNA:AT23738, BcDNA:AT10229" "IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG11165 16-Dec-15 2015_12 viable FBgn0033600 Cpr47Ec Cuticular protein 47Ec http://flybase.net/reports/FBgn0033600.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr47Ec, Cpr47eg, CG9077" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG9077 16-Dec-15 2015_12 viable FBgn0265095 CR44200 http://flybase.net/reports/FBgn0265095.html non_protein_coding_gene lincRNA.260 CR44200 16-Dec-15 2015_12 FBgn0001874 l(1)XN75b lethal (1) XN75b http://flybase.net/reports/FBgn0001874.html gene 16-Dec-15 2015_12 FBgn0002763 mit(1)13 mitotic 13 http://flybase.net/reports/FBgn0002763.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0005726 l(1)TK136 lethal (1) TK136 http://flybase.net/reports/FBgn0005726.html gene l136 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina,retina,photoreceptor cell,ectopic" FBgn0067759 l(1)G0021 lethal (1) G0021 http://flybase.net/reports/FBgn0067759.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0052698 CG32698 http://flybase.net/reports/FBgn0052698.html "FBgn0030152, FBgn0030153" protein_coding_gene 0004089=carbonate dehydratase activity "CG9683, CG9678" "IPR023561=Carbonic anhydrase, alpha-class, IPR001148=Alpha carbonic anhydrase" CG32698 16-Dec-15 2015_12 "ENSDARG00000009568(LOC568543),ENSDARG00000052644(ca10a)" "WBGene00000280(cah-2),WBGene00000279(cah-1)" "ENSXETG00000001296(CA10),ENSXETG00000014383(CA11)" "ENSMUSG00000056158(Car10),ENSMUSG00000003273(Car11)" "ENSG00000154975(CA10),ENSG00000063180(CA11)" "viable,fertile,lethal" FBgn0001909 l(2)24Fa lethal (2) 24Fa http://flybase.net/reports/FBgn0001909.html gene "jf6, l(2)jf5, l(2)jf6" 16-Dec-15 2015_12 lethal FBgn0065589 l(2)SH0906 lethal (2) SH0906 http://flybase.net/reports/FBgn0065589.html gene l(2)SH2 0906 16-Dec-15 2015_12 "lethal,recessive" FBgn0069965 CG41042 http://flybase.net/reports/FBgn0069965.html FBan0041042 protein_coding_gene 16-Dec-15 2015_12 FBgn0000036 nAChRë±1 nicotinic Acetylcholine Receptor ë±1 http://flybase.net/reports/FBgn0000036.html protein_coding_gene "0015464=acetylcholine receptor activity, 0004889=acetylcholine-activated cation-selective channel activity" "0006812=cation transport, 0017085=response to insecticide, 0007271=synaptic transmission, cholinergic" "0005892=acetylcholine-gated channel complex, 0045211=postsynaptic membrane, 0005887=integral component of plasma membrane" "nAChRalpha-96Aa, ALs, alpha1, Dalpha1, alpha-like-subunit, alpha-like, dALS, CG5610-PA, nAChR, alpha-Like Subunit, Acr96Aa, nAcRalpha-96Aa, NAcRa96Aa, nAcr96Aa, nAcRs, AcrB, nAChRalpha1, ALS, CG5610, alpha-like subunit, Acr96A, nicotinic acetylcholine receptor alpha-like, nicotinic Acetylcholine Receptor alpha 96Aa, Nicotinic Acetylcholine Receptor alpha-96Aa, als" "IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR002394=Nicotinic acetylcholine receptor, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain" CG5610 16-Dec-15 2015_12 "ENSDARG00000057025(chrna2b),ENSDARG00000006602(chrna2a),ENSDARG00000058393(chrna4),ENSDARG00000070724(LOC563696),ENSDARG00000057848,ENSDARG00000054497(LOC568467),ENSDARG00000055559(chrna6)" WBGene00006774(unc-38) ENSXETG00000017553(CHRNA2) "ENSMUSG00000032303(Chrna3),ENSMUSG00000031491(Chrna6),ENSMUSG00000027577(Chrna4),ENSMUSG00000022041(Chrna2)" "ENSG00000101204(CHRNA4),ENSG00000120903(CHRNA2),ENSG00000080644(CHRNA3),ENSG00000147434(CHRNA6)" larval stage " larval brain | restricted

, fat body

" "viable,chemical resistant,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036754 CG5589 http://flybase.net/reports/FBgn0036754.html protein_coding_gene "0005524=ATP binding, 0003729=mRNA binding, 0004004=ATP-dependent RNA helicase activity" "cg5589, DmRH17" "IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG5589 16-Dec-15 2015_12 YGL171W(ROK1) WBGene00011032(R05D11.4) ENSXETG00000025903(ddx52) ENSG00000141141(DDX52) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0050376 CG30376 http://flybase.net/reports/FBgn0050376.html FBgn0061438 protein_coding_gene BcDNA:AT30260 CG30376 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0065400 l(2)SH1604 lethal (2) SH1604 http://flybase.net/reports/FBgn0065400.html gene l(2)SH2 1604 16-Dec-15 2015_12 "lethal,recessive" FBgn0031563 CG10031 http://flybase.net/reports/FBgn0031563.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG10031 16-Dec-15 2015_12 ENSG00000101446(SPINT3) viable DRSC00286 K 0.083435295 -0.381492381 0.469131226 -0.019625059 -0.673698093 -1.724764975 FBgn0260940 lsn larsen http://flybase.net/reports/FBgn0260940.html "FBgn0067728, FBgn0038908" protein_coding_gene "0032509=endosome transport via multivesicular body sorting pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0008283=cell proliferation, 0008593=regulation of Notch signaling pathway, 0042981=regulation of apoptotic process, 0036258=multivesicular body assembly, 0045450=bicoid mRNA localization" 0000814=ESCRT II complex "vps22, CG6637, Lsn, Vps22" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR007286=EAP30, IPR016689=ESCRT-2 complex, Snf8" CG6637 16-Dec-15 2015_12 "ENSDARG00000052510(snf8),ENSDARG00000058076" YPL002C(SNF8) WBGene00016167(vps-22) ENSXETG00000022819(SNF8_XENTR) ENSMUSG00000006058(Snf8) ENSG00000159210(SNF8) FBgn0069986 BG02131 BG02131 http://flybase.net/reports/FBgn0069986.html gene 16-Dec-15 2015_12 stress response defective FBgn0060559 l(3)S097201b lethal (3) S097201b http://flybase.net/reports/FBgn0060559.html gene 0972/01 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040606 CG6503 http://flybase.net/reports/FBgn0040606.html FBgn0061371 protein_coding_gene "CT20261, BcDNA:RH63361, putative noncoding RNA 007:3R, pncr007:3R" CG6503 16-Dec-15 2015_12 viable FBgn0263554 mir-4952 mir-4952 stem loop http://flybase.net/reports/FBgn0263554.html miRNA_gene "dme-mir-4952, CR43539" CR43539 16-Dec-15 2015_12 FBgn0036891 CG9372 http://flybase.net/reports/FBgn0036891.html protein_coding_gene "0008236=serine-type peptidase activity, 0004252=serine-type endopeptidase activity" "0006508=proteolysis, 0009620=response to fungus, 0048812=neuron projection morphogenesis" "c-SP34, SP34" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP" CG9372 16-Dec-15 2015_12 WBGene00006619(try-1) "ENSXETG00000002964(proc),ENSXETG00000001932(F7),ENSXETG00000025492(f10),ENSXETG00000003472(f9),ENSXETG00000001982(BC089747.1)" viable FBgn0026228 l(1)16Fm lethal (1) 16Fm http://flybase.net/reports/FBgn0026228.html gene HL-XII 16-Dec-15 2015_12 "lethal,recessive" FBgn0039707 CG15510 http://flybase.net/reports/FBgn0039707.html FBgn0063334 protein_coding_gene BcDNA:AT14346 "IPR024460=Protein of unknown function DUF1074, IPR009071=High mobility group box domain" CG15510 16-Dec-15 2015_12 FBgn0034551 CG15225 http://flybase.net/reports/FBgn0034551.html protein_coding_gene 0005615=extracellular space CG15225 16-Dec-15 2015_12 viable FBgn0031224 CG11454 http://flybase.net/reports/FBgn0031224.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" cg11454 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG11454 16-Dec-15 2015_12 ENSDARG00000020841(zgc:77304) ENSMUSG00000042396(Rbm7) ENSG00000076053(RBM7) viable FBgn0066349 l(3)99DEf lethal (3) 99DEf http://flybase.net/reports/FBgn0066349.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003965 v vermilion http://flybase.net/reports/FBgn0003965.html protein_coding_gene "0020037=heme binding, 0004833=tryptophan 2,3-dioxygenase activity" "0006569=tryptophan catabolic process, 0006727=ommochrome biosynthetic process, 0019441=tryptophan catabolic process to kynurenine, 0019442=tryptophan catabolic process to acetyl-CoA, 0048072=compound eye pigmentation, 0070189=kynurenine metabolic process, 1901216=positive regulation of neuron death" "Vermillion, TDO, Ver, Tryptophan 2,3-dioxygenase, DmTDO, Vermilion, NP_511113, vm, ver, CG2155, 152559_at, vermillion" "IPR004981=Tryptophan 2,3-dioxygenase" CG2155 16-Dec-15 2015_12 "ENSDARG00000071429(tdo2a),ENSDARG00000023176(tdo2b)" WBGene00016201(C28H8.11) ENSXETG00000022396(Q5EBG2_XENTR) ENSMUSG00000028011(Tdo2) ENSG00000151790(TDO2) " adult stage , embryonic stage -- adult stage "

{ ^ su(s)35 } "fertile,viable,visible,recessive,eye color defective,male,long lived,male sterile,wild-type,male fertile,lethal,body color defective,female sterile,sterile" "pigment cell,ocellus pigment granule,eye" FBgn0040097 lectin-30A lectin-30A http://flybase.net/reports/FBgn0040097.html FBgn0032106 protein_coding_gene "0030246=carbohydrate binding, 0005534=galactose binding" 0032504=multicellular organism reproduction 0005615=extracellular space "AC005889a, CG17011, AC 005889A, Lectin-30A, Lectin30A" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG17011 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000008874(Clec3a),ENSMUSG00000025784(Clec3b),ENSMUSG00000004473(Clec11a)" ENSG00000163815(CLEC3B) "viable,visible" "trichogen cell,mesothoracic tergum" DRSC02560 K 0.80405199 0.220464309 0.357874715 -0.161842736 1.059307675 1.62267659 FBgn0264476 CR43884 http://flybase.net/reports/FBgn0264476.html non_protein_coding_gene CR43884 16-Dec-15 2015_12 FBgn0053958 CG33958 http://flybase.net/reports/FBgn0053958.html "FBtr0086770, FBtr0086769, FBpp0085949, FBpp0085948, FBgn0034316, FBgn0034319" protein_coding_gene "0004872=receptor activity, 0004383=guanylate cyclase activity" "0006182=cGMP biosynthetic process, 0035556=intracellular signal transduction" "GYC, CG14501, CG5719" "IPR013587=Nitrate/nitrite sensing protein, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR011645=Haem NO binding associated" CG33958 16-Dec-15 2015_12 "viable,fertile" FBgn0277423 l(3)psg27 http://flybase.net/reports/FBgn0277423.html gene psg27 16-Dec-15 2015_12 FBgn0028735 F8 F8 http://flybase.net/reports/FBgn0028735.html gene 16-Dec-15 2015_12 FBgn0020282 l(3)rF149 lethal (3) rF149 http://flybase.net/reports/FBgn0020282.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0062521 lgs::pygo lgs::pygo http://flybase.net/reports/FBgn0062521.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0028533 CG7953 http://flybase.net/reports/FBgn0028533.html FBgn0044554 protein_coding_gene "anon-WO0140519.73, BG:DS00941.14, DS00941.14" IPR010562=Haemolymph juvenile hormone binding CG7953 16-Dec-15 2015_12 viable FBgn0058323 CG40323 http://flybase.net/reports/FBgn0058323.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065431 l(2)SH1495 lethal (2) SH1495 http://flybase.net/reports/FBgn0065431.html gene l(2)SH2 1495 16-Dec-15 2015_12 "lethal,recessive" FBgn0030482 CG1673 http://flybase.net/reports/FBgn0030482.html protein_coding_gene 0004084=branched-chain-amino-acid transaminase activity 0009082=branched-chain amino acid biosynthetic process "0005737=cytoplasm, 0005739=mitochondrion" "IPR005786=Branched-chain amino acid aminotransferase II, IPR001544=Aminotransferase class IV, IPR018300=Aminotransferase, class IV, conserved site" CG1673 16-Dec-15 2015_12 "ENSDARG00000045568(bcat1),ENSDARG00000054849(bcat2)" "YJR148W(BAT2),YHR208W(BAT1)" WBGene00001149(bcat-1) ENSXETG00000025501(Q6DIN6_XENTR) "ENSMUSG00000030268(Bcat1),ENSMUSG00000030826(Bcat2)" "ENSG00000060982(BCAT1),ENSG00000105552(BCAT2)" "viable,body color defective" mesothoracic tergum FBgn0262617 CG43143 http://flybase.net/reports/FBgn0262617.html "FBgn0037804, FBgn0037805, FBgn0037806" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation "0005737=cytoplasm, 0005634=nucleus" "Omphk1, CG11870, CG11871, EMK/KIAA0537, NUAK, CG11872" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG43143 16-Dec-15 2015_12 YKL101W(HSL1) FBgn0064227 Rdh Rdh http://flybase.net/reports/FBgn0064227.html FBgn0035465 protein_coding_gene "CG14975, Red-herring" CG14975 16-Dec-15 2015_12 long lived FBgn0022394 Hex2 Hexokinase 2 http://flybase.net/reports/FBgn0022394.html gene "HEX, hexokinase, HEX-2, HK, Hexokinase" 16-Dec-15 2015_12 FBgn0034093 CG15706 http://flybase.net/reports/FBgn0034093.html protein_coding_gene MFSD6 "IPR020846=Major facilitator superfamily domain, IPR024989=Major facilitator superfamily associated domain" CG15706 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0265808 CR44597 http://flybase.net/reports/FBgn0265808.html non_protein_coding_gene lincRNA.119 CR44597 16-Dec-15 2015_12 FBgn0014268 l(2)k08634 lethal (2) k08634 http://flybase.net/reports/FBgn0014268.html gene 0048542=lymph gland development l(2)86/34 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0267220 CR45660 http://flybase.net/reports/FBgn0267220.html non_protein_coding_gene CR45660 16-Dec-15 2015_12 FBgn0028436 ECSIT ECSIT http://flybase.net/reports/FBgn0028436.html protein_coding_gene "0005515=protein binding, 0016651=oxidoreductase activity, acting on NAD(P)H" "0007165=signal transduction, 0008063=Toll signaling pathway, 0045087=innate immune response, 0051341=regulation of oxidoreductase activity, 0006952=defense response" "0005634=nucleus, 0005737=cytoplasm, 0005739=mitochondrion" "DmECSIT, CG10610, dECSIT" "IPR029342=ECSIT, C-terminal domain, IPR010418=ECSIT" CG10610 16-Dec-15 2015_12 ENSDARG00000062834(ecsit) WBGene00021202(Y17G9B.5) ENSXETG00000016738(ECSIT) ENSMUSG00000066839(Ecsit) ENSG00000130159(ECSIT) "viable,fertile" FBgn0060682 l(3)S076201b lethal (3) S076201b http://flybase.net/reports/FBgn0060682.html gene 0762/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0014217 l(2)31Cb lethal (2) 31Cb http://flybase.net/reports/FBgn0014217.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259263 EP-332 http://flybase.net/reports/FBgn0259263.html gene 16-Dec-15 2015_12 visible wing FBgn0003306 Rw Rough wing http://flybase.net/reports/FBgn0003306.html gene 16-Dec-15 2015_12 "female sterile,dominant" "wing,wing vein,antenna,ectopic" FBgn0259337 EP-23 http://flybase.net/reports/FBgn0259337.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta" FBgn0085315 CG34286 http://flybase.net/reports/FBgn0085315.html protein_coding_gene CG34286 16-Dec-15 2015_12 FBgn0022307 l(1)L19.1 lethal (1) L19.1 http://flybase.net/reports/FBgn0022307.html gene L19.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0043561 Su(hh)VI Su(hh)VI http://flybase.net/reports/FBgn0043561.html gene 16-Dec-15 2015_12 FBgn0263976 CR43728 http://flybase.net/reports/FBgn0263976.html non_protein_coding_gene CR43728 16-Dec-15 2015_12 FBgn0044095 E(rst)D17 E(rst)D17 http://flybase.net/reports/FBgn0044095.html gene 0001745=compound eye morphogenesis D17 16-Dec-15 2015_12 viable FBgn0028653 anon-47Ec anon-47Ec http://flybase.net/reports/FBgn0028653.html gene 3B1 16-Dec-15 2015_12 FBgn0039621 CG14518 http://flybase.net/reports/FBgn0039621.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG14518 16-Dec-15 2015_12 "viable,fertile" FBgn0065154 l(3)SH054 lethal (3) SH054 http://flybase.net/reports/FBgn0065154.html gene l(2)SH3 054 16-Dec-15 2015_12 "lethal,recessive" FBgn0022272 l(2)k00224 lethal (2) k00224 http://flybase.net/reports/FBgn0022272.html gene 16-Dec-15 2015_12 "visible,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,wing vein,wing" FBgn0037892 mRpL40 mitochondrial ribosomal protein L40 http://flybase.net/reports/FBgn0037892.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0022008=neurogenesis" 0005762=mitochondrial large ribosomal subunit "MRPL22(24), CG5242, mRpL22-24, mitochondrial ribosomal protein L22/24" "IPR019192=Ribosomal protein L28/L40, mitochondrial" CG5242 16-Dec-15 2015_12 ENSDARG00000043554(mrpl40) WBGene00018793(F54C4.1) ENSXETG00000018600(MRPL40) ENSMUSG00000022706(Mrpl40) ENSG00000185608(MRPL40) "visible,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "trichogen cell,mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0053169 CG33169 http://flybase.net/reports/FBgn0053169.html "FBgn0037198, FBgn0044457, FBgn0047004" protein_coding_gene "unnamed, EP3524, CG8244, BcDNA:RH56317" IPR027960=Domian of unknown function DUF4519 CG33169 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,female fertile" "intersegmental nerve,trichogen cell,mesothoracic tergum" FBgn0259339 EP-878 http://flybase.net/reports/FBgn0259339.html gene 16-Dec-15 2015_12 visible wing FBgn0260266 GSd212 http://flybase.net/reports/FBgn0260266.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0022743 anon-UJ4c anon-UJ4c http://flybase.net/reports/FBgn0022743.html gene 16-Dec-15 2015_12 FBgn0000667 Actn ë± actinin http://flybase.net/reports/FBgn0000667.html protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding, 0005515=protein binding, 0051015=actin filament binding" "0051764=actin crosslink formation, 0031532=actin cytoskeleton reorganization, 0051017=actin filament bundle assembly, 0007016=cytoskeletal anchoring at plasma membrane, 0045214=sarcomere organization, 0007629=flight behavior" "0005925=focal adhesion, 0030018=Z disc" "ACTN, HM-29, CT14163, l(1)EA82, y, EG:133E12.1, flightless-A, actn, alphaActn, lethal(1)2cb, GA17, Alpha-actinin, CG4376, fliA, CT14232, a-actinin, flightless A, l(1)2Cb, alpha actinin, alpha-actinin, alpha-Actinin" "IPR014837=EF-hand, Ca insensitive, IPR002017=Spectrin repeat, IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR018159=Spectrin/alpha-actinin, IPR001715=Calponin homology domain, IPR011992=EF-hand domain pair, IPR001589=Actinin-type actin-binding domain, conserved site, IPR026921=Alpha-actinin 1" CG4376 16-Dec-15 2015_12 "ENSDARG00000071090(actn2),ENSDARG00000013755(actn3a),ENSDARG00000001431(actn3b),ENSDARG00000007219(actn1)" WBGene00000228(atn-1) "ENSXETG00000011409(),ENSXETG00000025296(Q6DF05_XENTR),ENSXETG00000017933(ACTN1),ENSXETG00000000040(Q6DFP7_XENTR)" "ENSMUSG00000015143(Actn1),ENSMUSG00000054808(Actn4),ENSMUSG00000052374(Actn2),ENSMUSG00000006457(Actn3)" "ENSG00000077522(ACTN2),ENSG00000072110(ACTN1),ENSG00000130402(ACTN4)" " pupal stage | mid-late , embryonic stage -- adult stage , embryonic stage | mid-late " adult stage muscle cell

"viable,fertile,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,flightless,cold sensitive,flight defective,heat sensitive,female fertile,semidominant,hypoactive,small body,polyphasic,lethal - all die before end of embryonic stage,some die during embryonic stage,visible" "third instar larva,somatic muscle,muscle cell,myofibril,indirect flight muscle,sarcomere,actin filament bundle & egg chamber,ovariole,egg,germline clone,actin filament & follicle cell | somatic clone,eye,Z discMef2.PR,trichogen cell" DRSC25653 K -0.29073372 0.237851182 -0.186165933 -0.078904112 -0.639887683 1.942805924 FBgn0066345 l(3)99DEj lethal (3) 99DEj http://flybase.net/reports/FBgn0066345.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267260 CR45696 http://flybase.net/reports/FBgn0267260.html non_protein_coding_gene lincRNA.169 CR45696 16-Dec-15 2015_12 FBgn0086035 snoRNA:Me18S-G642 http://flybase.net/reports/FBgn0086035.html snoRNA_gene "Me18S-Gm642, CR34664" CR34664 16-Dec-15 2015_12 FBgn0061091 l(3)S011302 lethal (3) S011302 http://flybase.net/reports/FBgn0061091.html gene 0113/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0083738 Dje Dje http://flybase.net/reports/FBgn0083738.html gene 16-Dec-15 2015_12 immune response defective FBgn0034097 CG3687 http://flybase.net/reports/FBgn0034097.html FBgn0061445 protein_coding_gene BcDNA:AT22273 CG3687 16-Dec-15 2015_12 viable FBgn0261857 CR42786 http://flybase.net/reports/FBgn0261857.html pseudogene_attribute lincRNA.821 CR42786 16-Dec-15 2015_12 FBgn0034300 CG5098 http://flybase.net/reports/FBgn0034300.html protein_coding_gene CG5098 16-Dec-15 2015_12 "ENSXETG00000012165(RAI1),ENSXETG00000013417(TCF20)" "ENSMUSG00000041852(Tcf20),ENSMUSG00000062115(Rai1)" "ENSG00000100207(TCF20),ENSG00000108557(RAI1)" lethal FBgn0267216 CR45656 http://flybase.net/reports/FBgn0267216.html non_protein_coding_gene CR45656 16-Dec-15 2015_12 FBgn0029521 Or1a Odorant receptor 1a http://flybase.net/reports/FBgn0029521.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0042048=olfactory behavior" "0032590=dendrite membrane, 0016021=integral component of membrane" "1A.1, OR1a, DOR68, CG17885, 1a" "IPR004117=Olfactory receptor, Drosophila" CG17885 16-Dec-15 2015_12 viable DRSC18689 I -2.188090806 0.167983671 -0.505942403 0.418849929 -0.231042621 -0.809183105 FBgn0082338 HM689 HM689 http://flybase.net/reports/FBgn0082338.html gene 16-Dec-15 2015_12 FBgn0053124 CG33124 http://flybase.net/reports/FBgn0053124.html FBgn0031396 protein_coding_gene 0005215=transporter activity "0055085=transmembrane transport, 0006810=transport" 0016020=membrane "CG10879, CG33124-PB, dSLC5A13" "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG33124 16-Dec-15 2015_12 YHL016C(DUR3) viable FBgn0024339 KHD-5 KH domain cDNA KHD-5 http://flybase.net/reports/FBgn0024339.html gene unnamed 16-Dec-15 2015_12 FBgn0085313 CG34284 http://flybase.net/reports/FBgn0085313.html protein_coding_gene CG34284 16-Dec-15 2015_12 FBgn0264492 CkIIë± casein kinase IIë± http://flybase.net/reports/FBgn0264492.html "FBgn0000258, FBgn0062248, FBgn0066006, FBgn0060573" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005515=protein binding, 0005524=ATP binding" "0048749=compound eye development, 0007310=oocyte dorsal/ventral axis specification, 0045475=locomotor rhythm, 0006468=protein phosphorylation, 0009267=cellular response to starvation, 0022416=chaeta development, 0045880=positive regulation of smoothened signaling pathway, 0007228=positive regulation of hh target transcription factor activity, 0060810=intracellular mRNA localization involved in pattern specification process, 0046331=lateral inhibition, 0007411=axon guidance, 0007623=circadian rhythm, 0030177=positive regulation of Wnt signaling pathway, 0007067=mitotic nuclear division, 0016055=Wnt signaling pathway, 0031647=regulation of protein stability, 0031397=negative regulation of protein ubiquitination" "0005634=nucleus, 0005956=protein kinase CK2 complex, 0005829=cytosol, 0005737=cytoplasm" "casein kinase II, CkII, lethal (3) S095808, CKII-alpha, Tik, casein kinase II alpha, CK-II, protein kinase CK2, CJIIalpha, CK-II alpha, CK-2, DmCK2alpha, dCK2alpha, CK II, CK2-alpha, casein kinase 2, CK2 alpha, CKIIalpha, CKII, alphaCK2, Casein kinase II alpha subunit, dCKII, 0958/08, Cask-II-a, anon-WO02059370.53, alpha subunit of Drosophila casein kinase II, NAP1-kinase, Casein kinase II-alpha subunit, CKIIa, Casein kinase II, dCKII alpha, CK2, DmCKIIalpha, CG17520, CK2alpha, CKIIalfa, CKII alpha, Timekeeper, l(3)S095808, ckIIalpha, Ck2alpha, CkIIalpha, CK2a, ck2alpha" "IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain" CG17520 16-Dec-15 2015_12 "ENSDARG00000002082(ck2a1),ENSDARG00000014222(zgc:86598)" YIL035C(CKA1) WBGene00002191(kin-3) ENSXETG00000013728(csnk2a2) ENSMUSG00000074698(Csnk2a1) ENSG00000101266(CSNK2A1) FBgn0052755 CG32755 http://flybase.net/reports/FBgn0052755.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG32755 16-Dec-15 2015_12 viable FBgn0058233 CG40233 http://flybase.net/reports/FBgn0058233.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011608 l(1)I32b6 lethal (1) I32b6 http://flybase.net/reports/FBgn0011608.html FBgn0010206 gene "l(1)I33b6, l(1)32b6" 16-Dec-15 2015_12 lethal FBgn0024991 CG2694 http://flybase.net/reports/FBgn0024991.html FBgn0024979 protein_coding_gene "EG:100G10.8, EG:95B7.10" IPR006640=SprT-like CG2694 16-Dec-15 2015_12 ENSG00000147174(ACRC) viable FBgn0003949 un uneven http://flybase.net/reports/FBgn0003949.html gene ro-63 16-Dec-15 2015_12 "viable,fertile,visible,recessive" "eye,wing,ommatidium,optic lobe,scutellum,scutellum & macrochaeta" FBgn0266331 CR44996 http://flybase.net/reports/FBgn0266331.html non_protein_coding_gene CR44996 16-Dec-15 2015_12 FBgn0037828 tomboy20 tomboy20 http://flybase.net/reports/FBgn0037828.html protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0006626=protein targeting to mitochondrion 0005742=mitochondrial outer membrane translocase complex "dtomboy20, CG14690" "IPR022422=Protein import receptor MAS20, metazoan, IPR023392=Mitochondrial outer membrane translocase complex, subunit Tom20 domain, IPR002056=Protein import receptor MAS20" CG14690 16-Dec-15 2015_12 YGR082W(TOM20) WBGene00009092(tomm-20) viable FBgn0032095 Toll-4 Toll-4 http://flybase.net/reports/FBgn0032095.html protein_coding_gene 0004888=transmembrane signaling receptor activity "0007165=signal transduction, 0006952=defense response, 0000281=mitotic cytokinesis" "0016021=integral component of membrane, 0005886=plasma membrane" "CG18241, CT29238, Tl-4, TL4, toll receptor, dToll4, Toll-like, dTLR4, toll" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR001611=Leucine-rich repeat, IPR000372=Leucine-rich repeat N-terminal domain, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain" CG18241 16-Dec-15 2015_12 "ENSDARG00000019742,ENSDARG00000022048(tlr4bb)" FBgn0060943 l(3)S039206b lethal (3) S039206b http://flybase.net/reports/FBgn0060943.html gene 0392/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0001702 l(1)ESHS23 lethal (1) ESHS23 http://flybase.net/reports/FBgn0001702.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003636 su(ve) suppressor of veinlet http://flybase.net/reports/FBgn0003636.html gene 16-Dec-15 2015_12 FBgn0265856 CR44645 http://flybase.net/reports/FBgn0265856.html non_protein_coding_gene CR44645 16-Dec-15 2015_12 FBgn0264834 CR44042 http://flybase.net/reports/FBgn0264834.html non_protein_coding_gene CR44042 16-Dec-15 2015_12 FBgn0051117 CG31117 http://flybase.net/reports/FBgn0051117.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024611 olf701 olfactory 701 http://flybase.net/reports/FBgn0024611.html gene 16-Dec-15 2015_12 FBgn0005743 l(1)TK235 lethal (1) TK235 http://flybase.net/reports/FBgn0005743.html gene l235 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0065125 l(3)SH141 lethal (3) SH141 http://flybase.net/reports/FBgn0065125.html gene l(2)SH3 141 16-Dec-15 2015_12 "lethal,recessive" FBgn0015943 furrow furrow http://flybase.net/reports/FBgn0015943.html gene 16-Dec-15 2015_12 FBgn0265253 CR44267 http://flybase.net/reports/FBgn0265253.html non_protein_coding_gene CR44267 16-Dec-15 2015_12 FBgn0052558 CR32558 http://flybase.net/reports/FBgn0052558.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0041773 amanda amanda http://flybase.net/reports/FBgn0041773.html gene ada 16-Dec-15 2015_12 "melanotic mass phenotype,recessive,lethal,hyperplasia" "salivary gland,melanotic mass,embryonic/larval brain" FBgn0052817 CG32817 http://flybase.net/reports/FBgn0052817.html protein_coding_gene IPR022773=Siva CG32817 16-Dec-15 2015_12 ENSXETG00000024697(TEgg104k06.1) ENSMUSG00000064326(Siva1) FBgn0001777 l(1)M58 lethal (1) M58 http://flybase.net/reports/FBgn0001777.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,wing" FBgn0085431 CG34402 http://flybase.net/reports/FBgn0085431.html "FBgn0038030, FBgn0051218, FBgn0038036, FBgn0038031" protein_coding_gene "sol-1, CG17756, CG4940, CG31218, CT39356, SOL-1, suppressor of Lurcher movement defect-1, CG17793" IPR000859=CUB domain CG34402 16-Dec-15 2015_12 "ENSDARG00000008450(LOC100002838),ENSDARG00000055575(pcolce2b),ENSDARG00000056913(si:ch211-237l4.5),ENSDARG00000052057(zgc:194993)" WBGene00004944(sol-1) DRSC15681 K 0.472735568 -0.456273087 -0.248648253 -0.096946189 -1.745926199 0.466052849 FBgn0084245 tre-3 tre-3 http://flybase.net/reports/FBgn0084245.html "CG34647, CR34647" 16-Dec-15 2015_12 FBgn0025133 su(RpII140Z36)S14 su(RpII140Z36)S14 http://flybase.net/reports/FBgn0025133.html gene Z36[S14] 16-Dec-15 2015_12 FBgn0064178 l(1)B.8 lethal (1) B.8 http://flybase.net/reports/FBgn0064178.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032111 CG13110 http://flybase.net/reports/FBgn0032111.html FBgn0047341 protein_coding_gene BcDNA:AT19071 CG13110 16-Dec-15 2015_12 viable FBgn0264394 CR43842 http://flybase.net/reports/FBgn0264394.html non_protein_coding_gene CR43842 16-Dec-15 2015_12 FBgn0000503 dss disturbed segmentation http://flybase.net/reports/FBgn0000503.html gene 16-Dec-15 2015_12 "male fertile,visible,viable,male,poor,female sterile,body color defective" "adult abdomen,adult abdomen & microchaeta,macrochaeta,eye" FBgn0030133 CG15316 http://flybase.net/reports/FBgn0030133.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053502 CG33502 http://flybase.net/reports/FBgn0053502.html "FBgn0042218, FBgn0063180" protein_coding_gene "0005506=iron ion binding, 0051536=iron-sulfur cluster binding" 0016226=iron-sulfur cluster assembly "BcDNA:GM32035, CG18856, unnamed" "IPR014824=Scaffold protein Nfu/NifU, N-terminal, IPR017065=NFU1 iron-sulfur cluster scaffold homologue, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001075=NIF system FeS cluster assembly, NifU, C-terminal" CG33502 16-Dec-15 2015_12 ENSDARG00000068125(hirip5) YKL040C(NFU1) WBGene00003064(lpd-8) ENSXETG00000008202(NFU1) ENSMUSG00000029993(Nfu1) ENSG00000169599(NFU1) FBgn0004529 l(4)102CDk lethal (4) 102CDk http://flybase.net/reports/FBgn0004529.html gene "l(4)21, l(4)ST-1, lethal(4) Solway, Tennessee-1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033377 Pmm45A Phosphomannomutase 45A http://flybase.net/reports/FBgn0033377.html protein_coding_gene "0004614=phosphoglucomutase activity, 0004615=phosphomannomutase activity, 0000287=magnesium ion binding" 0016052=carbohydrate catabolic process 0005829=cytosol CG8073 "IPR016055=Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR005841=Alpha-D-phosphohexomutase superfamily, IPR005846=Alpha-D-phosphohexomutase, alpha/beta/alpha domain III, IPR005845=Alpha-D-phosphohexomutase, alpha/beta/alpha domain II, IPR005843=Alpha-D-phosphohexomutase, C-terminal, IPR005844=Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR016066=Alpha-D-phosphohexomutase, conserved site" CG8073 16-Dec-15 2015_12 "ENSDARG00000018178(pgm2),ENSDARG00000014704(pgm2l1)" YMR278W(PGM3) WBGene00012803(Y43F4B.5) ENSXETG00000022805(PGM2L1) "ENSMUSG00000030729(Pgm2l1),ENSMUSG00000029171(Pgm1)" "ENSG00000165434(PGM2L1),ENSG00000169299(PGM2)" viable FBgn0016639 ER2-3 ER2-3 http://flybase.net/reports/FBgn0016639.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036232 CG14125 http://flybase.net/reports/FBgn0036232.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "IPR002557=Chitin binding domain, IPR006970=PT repeat" CG14125 16-Dec-15 2015_12 "ENSDARG00000054895,ENSDARG00000053408,ENSDARG00000055574" viable FBgn0030927 CG15046 http://flybase.net/reports/FBgn0030927.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR006604=Disulphide knot CLIP, IPR009003=Peptidase S1, PA clan" CG15046 16-Dec-15 2015_12 viable FBgn0039552 CG12426 http://flybase.net/reports/FBgn0039552.html protein_coding_gene CG12426 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001752 l(1)J1024 lethal (1) J1024 http://flybase.net/reports/FBgn0001752.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" "spermatid,testis" FBgn0010175 RpA-8 Replication Protein A 8 http://flybase.net/reports/FBgn0010175.html gene 0003697=single-stranded DNA binding 0006261=DNA-dependent DNA replication "0005634=nucleus, 0005662=DNA replication factor A complex" "DRP-A, DmRPA, D-SSB, Drosophila Replication Protein A, Single stranded-binding protein 8, Ssb-8, RP-A, RPA, dRP-A" 16-Dec-15 2015_12 embryonic stage FBgn0029948 CheA7a Chemosensory protein A 7a http://flybase.net/reports/FBgn0029948.html protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG15033, CheA7a" "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG15033 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0265583 CR44410 http://flybase.net/reports/FBgn0265583.html non_protein_coding_gene CR44410 16-Dec-15 2015_12 FBgn0000110 apx apexless http://flybase.net/reports/FBgn0000110.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,male fertile,female fertile,reduced,female sterile,partially" "eye,ommatidium,wing,wing vein L1,wing vein L4,wing vein L5,costal vein,wing vein L3" FBgn0020222 Chr2 Chloroform resistant 2 http://flybase.net/reports/FBgn0020222.html gene unnamed 16-Dec-15 2015_12 "chemical resistant,maternal effect,semidominant" FBgn0034731 CG10384 http://flybase.net/reports/FBgn0034731.html protein_coding_gene 0003723=RNA binding cg10384 "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG10384 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033366 Ance-4 Ance-4 http://flybase.net/reports/FBgn0033366.html protein_coding_gene "0008241=peptidyl-dipeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis 0016020=membrane "ance-4, CG8196" "IPR001548=Peptidase M2, peptidyl-dipeptidase A" CG8196 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0065502 l(2)SH1205 lethal (2) SH1205 http://flybase.net/reports/FBgn0065502.html gene l(2)SH2 1205 16-Dec-15 2015_12 "lethal,recessive" FBgn0036158 CG6149 http://flybase.net/reports/FBgn0036158.html protein_coding_gene 0016021=integral component of membrane IPR006838=FAR-17a/AIG1-like protein CG6149 16-Dec-15 2015_12 "ENSDARG00000007171(aig1),ENSDARG00000037810(zgc:112175)" "WBGene00007995(C37E2.3),WBGene00007994(C37E2.2)" "ENSXETG00000009792(AIG1),ENSXETG00000019224(C6orf105)" ENSMUSG00000019806(Aig1) ENSG00000146416(AIG1) viable FBgn0067377 l(2)NC114 lethal (2) NC114 http://flybase.net/reports/FBgn0067377.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0054052 CR34052 http://flybase.net/reports/FBgn0054052.html FBgn0082837 non_protein_coding_gene "BP1069, unnamed, CG34052" CR34052 16-Dec-15 2015_12 FBgn0003443 small-narrow small narrow http://flybase.net/reports/FBgn0003443.html gene smn 16-Dec-15 2015_12 "viable,poor,male sterile,visible" "adult abdomen,wing" FBgn0265804 CR44593 http://flybase.net/reports/FBgn0265804.html non_protein_coding_gene "Mgn00376, Mgn00375" CR44593 16-Dec-15 2015_12 FBgn0038016 MBD-R2 MBD-R2 http://flybase.net/reports/FBgn0038016.html FBgn0038015 protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" "0022008=neurogenesis, 0007095=mitotic G2 DNA damage checkpoint, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0044545=NSL complex, 0035327=transcriptionally active chromatin, 0005705=polytene chromosome interband" "mbd-R2, CG10042, Mbdr2, dMBD-R2, Mbrd2, Dm Tam3, CG17393, MBD, TAM3, MBDR2" "IPR007087=Zinc finger, C2H2, IPR001739=Methyl-CpG DNA binding, IPR001965=Zinc finger, PHD-type, IPR015880=Zinc finger, C2H2-like, IPR016177=DNA-binding domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR006612=Zinc finger, C2CH-type" CG10042 16-Dec-15 2015_12 "ENSDARG00000038737(phf20b),ENSDARG00000002750(phf20a)" "ENSMUSG00000038116(Phf20),ENSMUSG00000072501(Phf20l1)" "ENSG00000025293(PHF20),ENSG00000129292(PHF20L1)" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC14180 E -1.185644906 -1.363071689 0.127676691 -4.337460815 -0.266085184 -0.813038192 FBgn0060801 l(3)S057115b lethal (3) S057115b http://flybase.net/reports/FBgn0060801.html gene 0571/15 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0060626 l(3)S087217b lethal (3) S087217b http://flybase.net/reports/FBgn0060626.html gene 0872/17 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020358 anon-28Aa anon-28Aa http://flybase.net/reports/FBgn0020358.html gene 551 16-Dec-15 2015_12 FBgn0262143 CG42869 http://flybase.net/reports/FBgn0262143.html protein_coding_gene CG42869 16-Dec-15 2015_12 FBgn0259300 C388 http://flybase.net/reports/FBgn0259300.html gene 16-Dec-15 2015_12 visible "wing hair,wing,chaeta" FBgn0050199 tRNA:CR30199 transfer RNA:CR30199 http://flybase.net/reports/FBgn0050199.html FBgn0060276 tRNA_gene 0033456=GCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:A:CGC:AE002575-b, AE002575.trna7-AlaCGC, chr2R.trna51-AlaCGC, CR30199, tRNA[[Ala]]" CR30199 16-Dec-15 2015_12 FBgn0060606 l(3)S090613b lethal (3) S090613b http://flybase.net/reports/FBgn0060606.html gene 0906/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0033067 CG11211 http://flybase.net/reports/FBgn0033067.html FBgn0062950 protein_coding_gene "0030246=carbohydrate binding, 0005537=mannose binding" BcDNA:RH26557 "IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin, IPR016187=C-type lectin fold, IPR016186=C-type lectin-like" CG11211 16-Dec-15 2015_12 "ENSDARG00000055833,ENSDARG00000069381(LOC100002476),ENSDARG00000051993(si:dkey-9i23.4),ENSDARG00000051992(si:dkey-9i23.5)" "viable,fertile" FBgn0015401 kni::knrl kni::knrl http://flybase.net/reports/FBgn0015401.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0264839 CR44047 http://flybase.net/reports/FBgn0264839.html non_protein_coding_gene CR44047 16-Dec-15 2015_12 FBgn0053554 Nipped-A Nipped-A http://flybase.net/reports/FBgn0053554.html "FBan0002905, FBtr0086095, FBan0033554, FBgn0002067, FBgn0002172, FBgn0004661, FBgn0020393, FBgn0033013, FBgn0039989" protein_coding_gene "0004402=histone acetyltransferase activity, 0004672=protein kinase activity, 0016773=phosphotransferase activity, alcohol group as acceptor" "0006355=regulation of transcription, DNA-templated, 0035222=wing disc pattern formation, 0045747=positive regulation of Notch signaling pathway, 0043966=histone H3 acetylation, 0000281=mitotic cytokinesis, 0016573=histone acetylation, 0006909=phagocytosis, 0043486=histone exchange" "0005634=nucleus, 0000123=histone acetyltransferase complex, 0005737=cytoplasm, 0005875=microtubule associated complex, 0005703=polytene chromosome puff, 0000124=SAGA complex, 0035267=NuA4 histone acetyltransferase complex, 0005700=polytene chromosome" "41Ah, lethal(2)41Ah, CG33554, TRA1, NipA, NippedA, dTra1, CG2905, Tra1, GroupV, l(2)41Ah, l(2)C123, CG10549, dTRRAP, l(2)EMS34-12, Tra-1, dmTRRAP, Nipped[A], Nip-A, Nipped A, Nipped, tra1, TRRAP" "IPR011009=Protein kinase-like domain, IPR003151=PIK-related kinase, FAT, IPR011989=Armadillo-like helical, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR014009=PIK-related kinase, IPR003152=FATC domain, IPR016024=Armadillo-type fold" CG33554 16-Dec-15 2015_12 YHR099W(TRA1) WBGene00007028(trr-1) ENSXETG00000020075() ENSMUSG00000045482(Trrap) ENSG00000196367(TRRAP) "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,lethal,partially,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell death" "wing,ocellus,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval brain,trichogen cell,mesothoracic tergum,imaginal disc" DRSC22386 IEK -2.471628354 -2.510615658 -3.383750856 -5.756960909 2.561044333 1.76685858 FBgn0037282 CG14657 http://flybase.net/reports/FBgn0037282.html protein_coding_gene CG14657 16-Dec-15 2015_12 viable FBgn0036826 arx asterix http://flybase.net/reports/FBgn0036826.html FBgn0062461 protein_coding_gene "0048477=oogenesis, 0045892=negative regulation of transcription, DNA-templated, 0031047=gene silencing by RNA" 0005634=nucleus "gametocyte-specific factor 1, Gtsf1, CG3893, DmGTSF1, BcDNA:LD18018" "IPR022776=TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG3893 16-Dec-15 2015_12 ENSDARG00000000887(zgc:56699) WBGene00020286(T06A10.3) ENSMUSG00000022487(Gtsf1) ENSG00000170627(GTSF1) "viable,female sterile,male fertile,female fertile" "ovary,polar follicle cell,oocyte" FBgn0026172 slow-phase slow phase http://flybase.net/reports/FBgn0026172.html gene sph 16-Dec-15 2015_12 FBgn0265793 CR44582 http://flybase.net/reports/FBgn0265793.html non_protein_coding_gene CR44582 16-Dec-15 2015_12 FBgn0030157 CG1468 http://flybase.net/reports/FBgn0030157.html FBgn0064963 protein_coding_gene BcDNA:GH18955 CG1468 16-Dec-15 2015_12 FBgn0266567 E(spl)më_-HLH::E(spl)më«-HLH http://flybase.net/reports/FBgn0266567.html engineered_fusion_gene 16-Dec-15 2015_12 visible "chaeta,mesothoracic tergum" FBgn0033888 CG18568 http://flybase.net/reports/FBgn0033888.html FBgn0044770 protein_coding_gene anon-WO0140519.113 CG18568 16-Dec-15 2015_12 viable FBgn0005445 l(1)v163 lethal (1) v163 http://flybase.net/reports/FBgn0005445.html gene l(1)163 16-Dec-15 2015_12 FBgn0016020 l(3)843 lethal (3) 843 http://flybase.net/reports/FBgn0016020.html gene 16-Dec-15 2015_12 FBgn0062600 Mod(var)1457 Mod(var)1457 http://flybase.net/reports/FBgn0062600.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1457 16-Dec-15 2015_12 "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0011932 tRNA:N5:42Ab transfer RNA:asn5:42Ab http://flybase.net/reports/FBgn0011932.html "FBgn0003759, FBgn0050308, FBgn0050511" tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:asn5:42Ab, asn-tRNA, CR30511, CR30308, chr2R.trna4-AsnGTT" CR30511 16-Dec-15 2015_12 FBgn0037676 CG8861 http://flybase.net/reports/FBgn0037676.html protein_coding_gene CG8861 16-Dec-15 2015_12 viable FBgn0030263 CG2076 http://flybase.net/reports/FBgn0030263.html protein_coding_gene IPR006214=Bax inhibitor 1-related CG2076 16-Dec-15 2015_12 ENSDARG00000014573(ghitm) WBGene00019664(K11H12.8) ENSMUSG00000041028(Ghitm) ENSG00000165678(GHITM) "viable,fertile" FBgn0002580 M(1)3E Minute (1) 3E http://flybase.net/reports/FBgn0002580.html gene 16-Dec-15 2015_12 FBgn0034438 CG9416 http://flybase.net/reports/FBgn0034438.html protein_coding_gene CG9416-PA IPR007484=Peptidase M28 CG9416 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0267773 CR46104 http://flybase.net/reports/FBgn0267773.html non_protein_coding_gene CR46104 16-Dec-15 2015_12 FBgn0034894 sigmar salivary glands marred http://flybase.net/reports/FBgn0034894.html protein_coding_gene 0043027=cysteine-type endopeptidase inhibitor activity involved in apoptotic process "0046330=positive regulation of JNK cascade, 0010506=regulation of autophagy, 0035071=salivary gland cell autophagic cell death, 0070507=regulation of microtubule cytoskeleton organization, 0048102=autophagic cell death, 0007435=salivary gland morphogenesis" "0042995=cell projection, 0005737=cytoplasm" CG4091 IPR008477=Protein of unknown function DUF758 CG4091 16-Dec-15 2015_12 "ENSDARG00000046148(tnfaip8l2b),ENSDARG00000043265(tnfaip8),ENSDARG00000010691,ENSDARG00000068318" "ENSXETG00000017562(tnfaip8),ENSXETG00000020757(TNFAIP8L3),ENSXETG00000008142(Q5BKH4_XENTR)" "ENSMUSG00000062210,ENSMUSG00000074345(Tnfaip8l3),ENSMUSG00000044469(Tnfaip8l1),ENSMUSG00000013707(Tnfaip8l2)" "ENSG00000145779(TNFAIP8),ENSG00000183578(TNFAIP8L3),ENSG00000185361(TNFAIP8L1),ENSG00000163154(TNFAIP8L2)" "lethal,viable,fertile,visible" trichogen cell FBgn0065382 l(2)SH1663 lethal (2) SH1663 http://flybase.net/reports/FBgn0065382.html gene l(2)SH2 1663 16-Dec-15 2015_12 "lethal,recessive" FBgn0084333 LA00007 LA00007 http://flybase.net/reports/FBgn0084333.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050479 CG30479 http://flybase.net/reports/FBgn0050479.html FBgn0033956 protein_coding_gene CG18373 CG30479 16-Dec-15 2015_12 viable FBgn0028137 l(3)S049217d lethal (3) S049217d http://flybase.net/reports/FBgn0028137.html gene "0492/17, l(3)S049217" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0051769 CG31769 http://flybase.net/reports/FBgn0051769.html FBgn0047028 protein_coding_gene BcDNA:RH26533 CG31769 16-Dec-15 2015_12 FBgn0259861 Su(Ste):CR42430 Su(Ste):CR42430 http://flybase.net/reports/FBgn0259861.html non_protein_coding_gene "CR42430, SuSte{}RR42320" CR42430 16-Dec-15 2015_12 FBgn0067771 fried fried http://flybase.net/reports/FBgn0067771.html gene "0048477=oogenesis, 0030717=karyosome formation" 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone,karyosome,nurse cell & nucleus | germ-line clone" FBgn0060438 l(3)S125006b lethal (3) S125006b http://flybase.net/reports/FBgn0060438.html gene 1250/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060454 l(3)S119016b lethal (3) S119016b http://flybase.net/reports/FBgn0060454.html gene 1190/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0029143 P(3)91A P(3)91A http://flybase.net/reports/FBgn0029143.html gene 16-Dec-15 2015_12 FBgn0267894 CR46182 http://flybase.net/reports/FBgn0267894.html pseudogene_attribute CG12717-related CR46182 16-Dec-15 2015_12 FBgn0067746 l(1)G0256 lethal (1) G0256 http://flybase.net/reports/FBgn0067746.html gene 16-Dec-15 2015_12 lethal FBgn0012036 Aldh Aldehyde dehydrogenase http://flybase.net/reports/FBgn0012036.html FBgn0032114 protein_coding_gene "0004029=aldehyde dehydrogenase (NAD) activity, 0008774=acetaldehyde dehydrogenase (acetylating) activity" "1901215=negative regulation of neuron death, 0045471=response to ethanol, 0006090=pyruvate metabolic process, 0055114=oxidation-reduction process, 0006117=acetaldehyde metabolic process" "0005759=mitochondrial matrix, 0005811=lipid particle, 0005739=mitochondrion, 0005737=cytoplasm" "146084_at, CG 3752, acetaldehyde dehydrogenase, ALDHA1, CG3752, Acetaldehyde dehydrogenase, aldehyde dehydrogenase, ALDH, ACDH" "IPR016160=Aldehyde dehydrogenase, cysteine active site, IPR015590=Aldehyde dehydrogenase domain, IPR016161=Aldehyde/histidinol dehydrogenase, IPR029510=Aldehyde dehydrogenase, glutamic acid active site, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR016163=Aldehyde dehydrogenase, C-terminal" CG3752 16-Dec-15 2015_12 "ENSDARG00000037094(LOC100332355),ENSDARG00000028087(aldh2a)" "YER073W(ALD5),YOR374W(ALD4),YPL061W(ALD6)" "WBGene00000107(alh-1),WBGene00000108(alh-2)" "ENSXETG00000020930(aldh2),ENSXETG00000014720(ALDH1B1)" "ENSMUSG00000029455(Aldh2),ENSMUSG00000035561(Aldh1b1)" "ENSG00000111275(ALDH2),ENSG00000137124(ALDH1B1)" "viable,chemical sensitive,starvation stress response defective,oxidative stress response defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0010148 l(3)96Ff lethal (3) 96Ff http://flybase.net/reports/FBgn0010148.html gene 16-Dec-15 2015_12 lethal FBgn0014225 l(2)31Ed lethal (2) 31Ed http://flybase.net/reports/FBgn0014225.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037193 CG17812 http://flybase.net/reports/FBgn0037193.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263528 mir-4970 mir-4970 stem loop http://flybase.net/reports/FBgn0263528.html miRNA_gene "dme-mir-4970, CR43513" CR43513 16-Dec-15 2015_12 FBgn0037709 CG8199 http://flybase.net/reports/FBgn0037709.html protein_coding_gene 0003863=3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 0046949=fatty-acyl-CoA biosynthetic process 0017086=3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex "IPR001017=Dehydrogenase, E1 component, IPR029061=Thiamin diphosphate-binding fold" CG8199 16-Dec-15 2015_12 ENSDARG00000040555(bckdha) WBGene00012713(Y39E4A.3) ENSXETG00000018753(BCKDHA) ENSMUSG00000060376(Bckdha) ENSG00000142046(TMEM91) viable FBgn0020287 l(3)02693 lethal (3) 02693 http://flybase.net/reports/FBgn0020287.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0266475 cacahuete http://flybase.net/reports/FBgn0266475.html gene 16-Dec-15 2015_12 lethal "egg chamber,germline clone,oocyte,ring canal" FBgn0266774 CR45239 http://flybase.net/reports/FBgn0266774.html non_protein_coding_gene CR45239 16-Dec-15 2015_12 FBgn0067039 XG47 XG47 http://flybase.net/reports/FBgn0067039.html gene 0035220=wing disc development 16-Dec-15 2015_12 "visible,viable" wing FBgn0004520 l(4)102CDd lethal (4) 102CDd http://flybase.net/reports/FBgn0004520.html gene l(4)5 16-Dec-15 2015_12 "lethal,recessive" FBgn0032907 CG9272 http://flybase.net/reports/FBgn0032907.html protein_coding_gene "0000703=oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity, 0051539=4 iron, 4 sulfur cluster binding, 0003677=DNA binding" "0006281=DNA repair, 0006285=base-excision repair, AP site formation, 0006974=cellular response to DNA damage stimulus" 0005634=nucleus 9272 "IPR011257=DNA glycosylase, IPR030841=Endonuclease III-like protein 1, IPR000445=Helix-hairpin-helix motif, IPR003651=Endonuclease III-like, iron-sulphur cluster loop motif, IPR003265=HhH-GPD domain, IPR023170=Helix-turn-helix, base-excision DNA repair, C-terminal, IPR004036=Endonuclease III-like, conserved site-2" CG9272 16-Dec-15 2015_12 ENSDARG00000042881(LOC100008368) "YOL043C(NTG2),YAL015C(NTG1)" WBGene00011201(nth-1) ENSXETG00000015934(nthl1) ENSMUSG00000041429(Nthl1) ENSG00000065057(NTHL1) viable FBgn0001924 l(2)25Ce lethal (2) 25Ce http://flybase.net/reports/FBgn0001924.html gene "jf19, l(2)jf19" 16-Dec-15 2015_12 lethal FBgn0010788 l(3)02733 lethal (3) 02733 http://flybase.net/reports/FBgn0010788.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267072 CR45516 http://flybase.net/reports/FBgn0267072.html non_protein_coding_gene CR45516 16-Dec-15 2015_12 FBgn0085593 CG41277 http://flybase.net/reports/FBgn0085593.html FBan0041277 protein_coding_gene 16-Dec-15 2015_12 FBgn0259535 B2007 http://flybase.net/reports/FBgn0259535.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,leg,wing,arista,third segment of antenna" FBgn0003069 pers persimmon http://flybase.net/reports/FBgn0003069.html gene 16-Dec-15 2015_12 "viable,fertile,eye color defective" "pigment cell,Malpighian tubule" FBgn0069187 l(3)c00213 lethal (3) c00213 http://flybase.net/reports/FBgn0069187.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0267900 CR46188 http://flybase.net/reports/FBgn0267900.html pseudogene_attribute CG12717-related CR46188 16-Dec-15 2015_12 FBgn0016845 l(1)N23 lethal (1) N23 http://flybase.net/reports/FBgn0016845.html gene N23 16-Dec-15 2015_12 "lethal,recessive" FBgn0053335 CG33335 http://flybase.net/reports/FBgn0053335.html protein_coding_gene 16-Dec-15 2015_12 FBgn0043982 Su(rst)E392 Su(rst)E392 http://flybase.net/reports/FBgn0043982.html gene 0001745=compound eye morphogenesis E392 16-Dec-15 2015_12 FBgn0037809 CG12818 http://flybase.net/reports/FBgn0037809.html protein_coding_gene 0005515=protein binding 0046331=lateral inhibition "IPR019339=CBF1-interacting co-repressor CIR, N-terminal domain" CG12818 16-Dec-15 2015_12 ENSDARG00000037633(leng1) WBGene00021208(Y18H1A.2) ENSXETG00000003171(LENG1) ENSMUSG00000078813(Leng1) ENSG00000105617(LENG1) "viable,visible" "chaeta,supernumerary" FBgn0065363 l(2)SH1725 lethal (2) SH1725 http://flybase.net/reports/FBgn0065363.html gene l(2)SH2 1725 16-Dec-15 2015_12 "lethal,recessive" FBgn0266867 CR45328 http://flybase.net/reports/FBgn0266867.html non_protein_coding_gene CR45328 16-Dec-15 2015_12 FBgn0260986 mei-38 meiotic 38 http://flybase.net/reports/FBgn0260986.html "FBgn0016035, FBgn0026871" protein_coding_gene 0008017=microtubule binding "0001578=microtubule bundle formation, 0000022=mitotic spindle elongation, 0007131=reciprocal meiotic recombination, 0000212=meiotic spindle organization, 0045143=homologous chromosome segregation, 0016321=female meiosis chromosome segregation, 0007052=mitotic spindle organization, 0032837=distributive segregation, 0007143=female meiotic division" "0072686=mitotic spindle, 0005819=spindle, 0005828=kinetochore microtubule, 0051233=spindle midzone, 0005827=polar microtubule" "Ssp1, EG:80H7.11, short spindle 1, Mei-38, mei-38, D-TPX2, ssp1, CG14781" CG14781 16-Dec-15 2015_12 "spindle microtubule & oocyte,spindle pole & oocyte,karyosome & oocyte,spindle microtubule & larval brain,spindle pole & larval brain" FBgn0083053 snoRNA:ë¬18S-1347b snoRNA:ë¬18S-1347b http://flybase.net/reports/FBgn0083053.html snoRNA_gene "chr2R:13657839..13657931, CR34545, psi18S-1347b, Psi18S-1347b" CR34545 16-Dec-15 2015_12 FBgn0031039 Shawn Shawn http://flybase.net/reports/FBgn0031039.html FBgn0053075 protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "CG33075, CG14209" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG14209 16-Dec-15 2015_12 "ENSDARG00000015856(slc25a40),ENSDARG00000007449(slc25a39)" YGR257C(MTM1) WBGene00007622(C16C10.1) "ENSXETG00000027655(BC075453.1),ENSXETG00000011613(BC088076.1)" "ENSMUSG00000054099(Slc25a40),ENSMUSG00000018677(Slc25a39)" "ENSG00000075303(SLC25A40),ENSG00000013306(SLC25A39)" FBgn0265272 CG30060 http://flybase.net/reports/FBgn0265272.html "FBgn0050060, FBgn0066869" protein_coding_gene anon-SAGE:Wang-129 IPR008914=Phosphatidylethanolamine-binding protein PEBP CG30060 16-Dec-15 2015_12 "YLR179C(),YLR178C(TFS1)" FBgn0058396 CG40396 http://flybase.net/reports/FBgn0058396.html FBgn0061436 protein_coding_gene BcDNA:AT30578 16-Dec-15 2015_12 DRSC21812 IE 0.549685848 -1.945275937 0.04330481 2.288341993 0.540464787 -0.091829053 FBgn0027493 AdSS Adenylosuccinate Synthetase http://flybase.net/reports/FBgn0027493.html protein_coding_gene "0005525=GTP binding, 0004019=adenylosuccinate synthase activity" "0022008=neurogenesis, 0006164=purine nucleotide biosynthetic process" "CG17273, BcDNA:LD32788, PURA_DROME" "IPR001114=Adenylosuccinate synthetase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR018220=Adenylosuccinate synthase, active site" CG17273 16-Dec-15 2015_12 "ENSDARG00000002071(adss),ENSDARG00000009867(adssl1),ENSDARG00000012399(adssl)" YNL220W(ADE12) WBGene00016509(C37H5.6) "ENSXETG00000024695(BC075419.1),ENSXETG00000014538(BC061354.1)" "ENSMUSG00000015961(Adss),ENSMUSG00000011148(Adssl1)" "ENSG00000035687(ADSS),ENSG00000185100(ADSSL1)" "lethal - all die during larval stage,recessive,long lived,lethal,neuroanatomy defective,viable" ganglion mother cell DRSC14162 K -1.165420469 0.037736422 -0.57451367 0.156889503 2.061754958 0.047266587 FBgn0067406 Pcp-1 Pcp-1 cuticular protein http://flybase.net/reports/FBgn0067406.html gene 16-Dec-15 2015_12 FBgn0026334 Svop SVtwo-related protein http://flybase.net/reports/FBgn0026334.html gene SVOP 16-Dec-15 2015_12 FBgn0083033 snoRNA:ë¬18S-525f snoRNA:ë¬18S-525f http://flybase.net/reports/FBgn0083033.html snoRNA_gene "CR34579, psi18S-525f" CR34579 16-Dec-15 2015_12 FBgn0261000 AGAR-52 Autosomal general anesthetic resistant 52 http://flybase.net/reports/FBgn0261000.html gene autosomal general anesthetic resistant 52 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0023116 anon-10Ar anon-10Ar http://flybase.net/reports/FBgn0023116.html gene 11 16-Dec-15 2015_12 FBgn0037707 RnpS1 RNA-binding protein S1 http://flybase.net/reports/FBgn0037707.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0000335=negative regulation of transposition, DNA-mediated, 0008380=RNA splicing" 0005654=nucleoplasm "CG16788, RNPS1, RRM-domain protein, cg16788, rnps1, DEK" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG16788 16-Dec-15 2015_12 ENSDARG00000015853 WBGene00004388(rnp-5) ENSXETG00000024439(rnps1) ENSMUSG00000034681(Rnps1) ENSG00000205937(RNPS1)

"neuroanatomy defective,female semi-sterile,female sterile" "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" DRSC15154 E 1.227943017 1.301145037 1.50919055 0.868104742 -0.394009413 0.135163129 FBgn0262794 CG43175 http://flybase.net/reports/FBgn0262794.html protein_coding_gene CG43175 16-Dec-15 2015_12 FBgn0022337 da::Drer\E12 E12 http://flybase.net/reports/FBgn0022337.html engineered_fusion_gene da::Brer\E12 16-Dec-15 2015_12 FBgn0028738 ETH Ecdysis triggering hormone http://flybase.net/reports/FBgn0028738.html FBgn0035067 protein_coding_gene "0001664=G-protein coupled receptor binding, 0005184=neuropeptide hormone activity, 0008255=ecdysis-triggering hormone activity, 0005102=receptor binding" "0018990=ecdysis, chitin-based cuticle, 0007218=neuropeptide signaling pathway" 0005615=extracellular space "CG18105, Ecdysis Triggering Hormone 1, Ecdysis-triggering hormone, DmETH, ecdysis triggering hormone-2, ETH2, ETH1, ecdysis-triggering-hormone-1, ETH-1, Drm-ETH-2, ecdysis-triggering hormone-1, ecdysis triggering hormone-1, eth, ETH-2, Drm-ETH-1, ecdysis triggering hormone, ecdysis-triggering hormone-2" CG18105 16-Dec-15 2015_12 "wild-type,behavior defective,lethal - all die before end of larval stage,some die during larval stage,recessive,viable" "tracheal system,trachea,embryonic/larval cuticle" FBgn0010187 tu(3)pb tu(3)pb http://flybase.net/reports/FBgn0010187.html gene "Tu-pb, tu-pb" 16-Dec-15 2015_12 melanotic mass phenotype proboscis FBgn0034935 Orcokinin Orcokinin http://flybase.net/reports/FBgn0034935.html FBgn0062962 protein_coding_gene "CG13565, BcDNA:RH09340" CG13565 16-Dec-15 2015_12 viable FBgn0000294 Cg63-64 Collagen-like 63-64 http://flybase.net/reports/FBgn0000294.html gene "DCg8, Cg8" 16-Dec-15 2015_12 FBgn0035551 CG7465 http://flybase.net/reports/FBgn0035551.html protein_coding_gene "IPR004019=YLP motif, IPR004011=GYR motif" CG7465 16-Dec-15 2015_12 "viable,visible" "trichogen cell,supernumerary,mesothoracic tergum" FBgn0037498 CG10029 http://flybase.net/reports/FBgn0037498.html protein_coding_gene "0015037=peptide disulfide oxidoreductase activity, 0003756=protein disulfide isomerase activity" "0006457=protein folding, 0045454=cell redox homeostasis" 0005783=endoplasmic reticulum "IPR012336=Thioredoxin-like fold, IPR013766=Thioredoxin domain" CG10029 16-Dec-15 2015_12 WBGene00016278(C30H7.2) ENSXETG00000013069(txndc4) viable FBgn0031240 CG3345 http://flybase.net/reports/FBgn0031240.html FBgn0044666 protein_coding_gene anon-WO0140519.207 CG3345 16-Dec-15 2015_12 ENSMUSG00000079606(Gm595) viable FBgn0011065 l(1)Q18 lethal (1) Q18 http://flybase.net/reports/FBgn0011065.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0031148 Cbs Cystathionine ë_-synthase http://flybase.net/reports/FBgn0031148.html protein_coding_gene 0004122=cystathionine beta-synthase activity "0006535=cysteine biosynthetic process from serine, 0019343=cysteine biosynthetic process via cystathionine, 0034976=response to endoplasmic reticulum stress, 0008340=determination of adult lifespan" 0005737=cytoplasm "Cystathionine &bgr-synthase, CG1753, dCBS, cystathionine &grb;-synthase, CBS, cystathionine beta-synthase, DmCBS" "IPR001926=Tryptophan synthase beta subunit-like PLP-dependent enzyme, IPR000644=CBS domain, IPR001216=Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site, IPR005857=Cystathionine beta-synthase" CG1753 16-Dec-15 2015_12 "ENSDARG00000010946(cbsb),ENSDARG00000053500(cbsa)" YGR155W(CYS4) "WBGene00007653(C17G1.7),WBGene00010759(K10H10.2),WBGene00019962(R08E5.2),WBGene00019096(F59A7.9)" ENSMUSG00000024039(Cbs) ENSG00000160200(CBS) "short lived,long lived,RU486 conditional,viable,fertile" FBgn0262967 CR43278 http://flybase.net/reports/FBgn0262967.html non_protein_coding_gene 0016021=integral component of membrane "CG43278, mdcds_60948" CR43278 16-Dec-15 2015_12 FBgn0046644 anon-38D.22 anon-38D.22 http://flybase.net/reports/FBgn0046644.html gene 38D.22 16-Dec-15 2015_12 FBgn0033483 egr eiger http://flybase.net/reports/FBgn0033483.html "FBgn0062838, FBgn0064801" protein_coding_gene "0005515=protein binding, 0032813=tumor necrosis factor receptor superfamily binding, 0005164=tumor necrosis factor receptor binding" "0045176=apical protein localization, 0070050=neuron cellular homeostasis, 0097191=extrinsic apoptotic signaling pathway, 0035006=melanization defense response, 0045167=asymmetric protein localization involved in cell fate determination, 0006915=apoptotic process, 1900074=negative regulation of neuromuscular synaptic transmission, 0043652=engulfment of apoptotic cell, 0007254=JNK cascade, 0050829=defense response to Gram-negative bacterium, 0045087=innate immune response, 0006955=immune response" "0005886=plasma membrane, 0044214=spanning component of plasma membrane" "dt1, Eiger, TNF-alpha, CG12919, BcDNA:RH51659, Ect1, Drosophila aspartate rich TNF homolog, Wengen, TNF, Egr, tumor necrosis factor family member DT1, regg1, darth, eiger, Regg1" "IPR021184=Tumour necrosis factor, conserved site, IPR008983=Tumour necrosis factor-like domain, IPR006052=Tumour necrosis factor domain" CG12919 16-Dec-15 2015_12 ENSMUSG00000018752(Tnfsf12-Tnfsf13) embryonic stage | cellular blastoderm dorsal ectoderm anlage

"immune response defective,viable,fertile,visible,size defective,increased cell death,cell death defective,nutrition conditional,feeding behavior defective,somatic clone,partially lethal - majority die,heat sensitive,partially lethal - majority live,temperature conditional,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage" "eye,plasmatocyte,wing disc | third instar larval stage,wing,macrochaeta & scutellum-537.4,macrochaeta & mesothoracic tergum-537.4,adult abdomen,embryonic/larval hemolymph,egg chamber,nutrition conditional,follicle cell,somatic clone,eye photoreceptor cell | third instar larval stage,embryonic/larval optic stalk,embryonic/larval hemolymph | third instar larval stage,eye-antennal disc,scutellum,wing margin,wing disc,ventral furrow" FBgn0021810 l(2)k16529 lethal (2) k16529 http://flybase.net/reports/FBgn0021810.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027117 mei-P15 mei-P15 http://flybase.net/reports/FBgn0027117.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0013515 l(1)14Ad lethal (1) 14Ad http://flybase.net/reports/FBgn0013515.html gene "XIV, l(1)XIV, l(1)13Fg" 16-Dec-15 2015_12 "lethal,recessive" FBgn0040817 CG14132 http://flybase.net/reports/FBgn0040817.html protein_coding_gene 0005615=extracellular space DIGF-7 IPR029277=Single domain Von Willebrand factor type C domain CG14132 16-Dec-15 2015_12 viable FBgn0032715 CG17597 http://flybase.net/reports/FBgn0032715.html protein_coding_gene 0003988=acetyl-CoA C-acyltransferase activity 0008152=metabolic process 0005777=peroxisome "IPR020617=Thiolase, C-terminal, IPR020613=Thiolase, conserved site, IPR020615=Thiolase, acyl-enzyme intermediate active site, IPR002155=Thiolase, IPR016039=Thiolase-like, IPR020616=Thiolase, N-terminal" CG17597 16-Dec-15 2015_12 ENSDARG00000012194(scp2) WBGene00013284(daf-22) ENSXETG00000024490(Q5EBE0_XENTR) ENSMUSG00000028603(Scp2) ENSG00000116171(SCP2) viable FBgn0013627 l(3)neo23 lethal (3) neo23 http://flybase.net/reports/FBgn0013627.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085228 CG34199 http://flybase.net/reports/FBgn0085228.html protein_coding_gene CG34199 16-Dec-15 2015_12 FBgn0011589 Elk Eag-like K+ channel http://flybase.net/reports/FBgn0011589.html protein_coding_gene "0005267=potassium channel activity, 0005249=voltage-gated potassium channel activity, 0000155=phosphorelay sensor kinase activity, 0022843=voltage-gated cation channel activity" "0006813=potassium ion transport, 0055085=transmembrane transport, 0000160=phosphorelay signal transduction system" 0008076=voltage-gated potassium channel complex "eag-like K[+] channel, elk, eag-like K+ channel, CG5076, dmELK" "IPR005821=Ion transport domain, IPR000014=PAS domain, IPR014710=RmlC-like jelly roll fold, IPR003938=Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR001610=PAC motif, IPR003950=Potassium channel, voltage-dependent, ELK, IPR000700=PAS-associated, C-terminal, IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain" CG5076 16-Dec-15 2015_12 "ENSDARG00000062640(kcnh8),ENSDARG00000062565(LOC100148126),ENSDARG00000061990,ENSDARG00000069560(LOC100006614)" "ENSXETG00000014005(KCNH8),ENSXETG00000001079(KCNH3)" "ENSMUSG00000035580,ENSMUSG00000035355(Kcnh4),ENSMUSG00000037579(Kcnh3)" "ENSG00000183960(KCNH8),ENSG00000089558(KCNH4),ENSG00000135519(KCNH3)" "partially lethal - majority die,some die during pupal stage,viable" FBgn0028023 l(3)S103710 lethal (3) S103710 http://flybase.net/reports/FBgn0028023.html gene 1037/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0051542 CG31542 http://flybase.net/reports/FBgn0051542.html "FBgn0045137, FBgn0045367, FBgn0045439, FBgn0063330" protein_coding_gene "NEST:bs29h01, NEST:bs01d10, NEST:bs08f12, BcDNA:AT15479" CG31542 16-Dec-15 2015_12 "viable,fertile" DRSC21544 E -1.496970381 -1.136386051 -1.161421121 -2.274157499 0.336180417 0.607748264 FBgn0025739 pon partner of numb http://flybase.net/reports/FBgn0025739.html protein_coding_gene "0055059=asymmetric neuroblast division, 0035050=embryonic heart tube development, 0008105=asymmetric protein localization" "0045180=basal cortex, 0005737=cytoplasm, 0005938=cell cortex, 0045178=basal part of cell" "Partner Of Numb, PON, CG3346, Partner of Numb, Partner of numb, Pon" CG3346 16-Dec-15 2015_12 embryonic stage " neuroblast

, myoblast

, sensory mother cell

" " prepupal stage , embryonic stage , embryonic stage | stage 13-14 , embryonic stage | stage 10-11 " " external sensory organ precursor cell && imaginal disc

, neuroblast

, sensory mother cell

, myoblast

" "viable,fertile,hyperplasia,somatic clone,neuroanatomy defective" "neuroblast,somatic clone,embryonic/larval pericardial cell,abdominal 2 lateral transverse muscle 3,abdominal 3 lateral transverse muscle 3,abdominal 4 lateral transverse muscle 3,abdominal 5 lateral transverse muscle 3,abdominal 6 lateral transverse muscle 3,abdominal 7 lateral transverse muscle 3,embryonic/larval somatic muscle" FBgn0037483 CG14609 http://flybase.net/reports/FBgn0037483.html protein_coding_gene CG14609 16-Dec-15 2015_12 FBgn0016712 Reg-17 Rhythmically expressed gene 17 http://flybase.net/reports/FBgn0016712.html gene "Drosophila Rhythmically expressed gene 17, Dreg-17" 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0265606 Prosë±4T1 "Proteasome ë±4 subunit, Testis-specific 1" http://flybase.net/reports/FBgn0265606.html "FBgn0017555, FBgn0017557, FBgn0011827" protein_coding_gene 0004298=threonine-type endopeptidase activity 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0019773=proteasome core complex, alpha-subunit complex" "pros28.1A, Prosalpha4T1, unnamed, Pros28.1A, Pros28.2, alpha4t1, dalpha7, Proteasome 28kD subunit 1A, CG17268, 20S proteasome, alpha4T1, testes-specific proteasome subunit, 20s proteasome, Proteasome 28kD subunit 2, alpha4t1_dm, a4-t1" "IPR023332=Proteasome A-type subunit, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR001353=Proteasome, subunit alpha/beta" CG17268 16-Dec-15 2015_12 ENSDARG00000010965(psma8) YOL038W(PRE6) WBGene00003925(pas-4) ENSXETG00000001998(psma7) "ENSMUSG00000036743(Psma8),ENSMUSG00000027566(Psma7)" "ENSG00000154611(PSMA8),ENSG00000101182(PSMA7)" DRSC28895 K -0.105060456 -0.465304183 -0.295765505 0.516458549 2.62304026 1.352178717 FBgn0005516 l(1)DC1112 lethal (1) DC1112 http://flybase.net/reports/FBgn0005516.html gene 16-Dec-15 2015_12 "short lived,recessive,lethal" FBgn0021841 l(2)k14902 lethal (2) k14902 http://flybase.net/reports/FBgn0021841.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032080 CG9525 http://flybase.net/reports/FBgn0032080.html protein_coding_gene 0003824=catalytic activity "0032504=multicellular organism reproduction, 0008152=metabolic process" 0005615=extracellular space gi7297470 "IPR004245=Protein of unknown function DUF229, IPR017850=Alkaline-phosphatase-like, core domain" CG9525 16-Dec-15 2015_12 DRSC03249 I 2.085457933 0.516635877 1.249179374 0.904306587 -1.178757528 -0.044796488 FBgn0023427 olfactory-defective-A odA http://flybase.net/reports/FBgn0023427.html gene odA 16-Dec-15 2015_12 "smell perception defective,recessive" FBgn0066361 john john http://flybase.net/reports/FBgn0066361.html gene "0007611=learning or memory, 0008355=olfactory learning, 0048149=behavioral response to ethanol" 16-Dec-15 2015_12 "learning defective,memory defective,chemical sensitive" FBgn0261992 CG42810 http://flybase.net/reports/FBgn0261992.html "FBgn0032526, FBan0016849" protein_coding_gene CG16849 CG42810 16-Dec-15 2015_12 viable FBgn0061143 l(3)S000616b lethal (3) S000616b http://flybase.net/reports/FBgn0061143.html gene 16-Jun 16-Dec-15 2015_12 lethal FBgn0015288 RpL22 Ribosomal protein L22 http://flybase.net/reports/FBgn0015288.html FBgn0025289 protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0040018=positive regulation of multicellular organism growth, 0007052=mitotic spindle organization" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "rpl22, L22, Rpl22, RL22_DROME, anon-EST:Posey53, RL22, PBP-12, RPL22, PARP-binding protein-12, ribosomal protein L22, Rp L22, EG:BACR19J1.4, CG7434, rpL22" IPR002671=Ribosomal protein L22e CG7434 16-Dec-15 2015_12 "lethal,recessive" DRSC22819 IEK -1.501733944 0.101010891 5.430292018 -3.853988658 0.132640886 3.696400528 FBgn0014897 anon-10Ad anon-10Ad http://flybase.net/reports/FBgn0014897.html gene unnamed 16-Dec-15 2015_12 FBgn0035104 CG13875 http://flybase.net/reports/FBgn0035104.html protein_coding_gene RE30146P IPR029071=Ubiquitin-related domain CG13875 16-Dec-15 2015_12 "ENSXETG00000019780(RASSF10),ENSXETG00000011745(RASSF9)" ENSMUSG00000044921(Rassf9) "viable,fertile" FBgn0041757 eth-as313 eth-as313 http://flybase.net/reports/FBgn0041757.html gene eth[as]313 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0040575 CG15922 http://flybase.net/reports/FBgn0040575.html FBgn0047024 protein_coding_gene BcDNA:RH34302 CG15922 16-Dec-15 2015_12 FBgn0041137 l(2)44Ea lethal (2) 44Ea http://flybase.net/reports/FBgn0041137.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0033688 Prp8 pre-mRNA processing factor 8 http://flybase.net/reports/FBgn0033688.html protein_coding_gene "0017070=U6 snRNA binding, 0030623=U5 snRNA binding, 0017069=snRNA binding" "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0005737=cytoplasm, 0005682=U5 snRNP, 0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex" "E-2e, CG8877, A1Z8U0, U5 small nuclear ribonucleoprotein-specific factor, prp8, Prp8" "IPR019580=Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding, IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR012592=PROCN domain, IPR019581=Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding, IPR027652=Pre-mRNA-processing-splicing factor 8, IPR012984=PROCT domain, IPR019582=RNA recognition motif, spliceosomal PrP8, IPR012591=PRO8NT domain, IPR021983=PRP8 domain IV core, IPR012337=Ribonuclease H-like domain" CG8877 16-Dec-15 2015_12 ENSDARG00000026180(prpf8) YHR165C(PRP8) WBGene00004187(prp-8) ENSXETG00000022259(PRPF8) ENSMUSG00000020850(Prpf8) ENSG00000174231(PRPF8) "increased cell death,small body,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,partially lethal - majority die,visible,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,wing disc,anterior crossvein,1st posterior cell,prothoracic gland | larval stage,scutellar bristle,wing" DRSC07293 I -0.734796401 2.267346494 -0.281473739 -1.026809643 -1.188915651 -0.818240457 FBgn0053386 5SrRNA:CR33386 5SrRNA:CR33386 http://flybase.net/reports/FBgn0053386.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33386 CR33386 16-Dec-15 2015_12 FBgn0060731 l(3)S067304 lethal (3) S067304 http://flybase.net/reports/FBgn0060731.html gene 0673/04 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0264879 CR44070 http://flybase.net/reports/FBgn0264879.html non_protein_coding_gene CR44070 16-Dec-15 2015_12 FBgn0032923 CG9248 http://flybase.net/reports/FBgn0032923.html protein_coding_gene 0003824=catalytic activity IPR001736=Phospholipase D/Transphosphatidylase CG9248 16-Dec-15 2015_12 ENSDARG00000061845(si:dkeyp-110e4.6) WBGene00017316(F09G2.8) ENSXETG00000016961(pld3) "ENSMUSG00000003363(Pld3),ENSMUSG00000052160(Pld4)" ENSG00000105223(PLD3) viable FBgn0003395 shm short macros http://flybase.net/reports/FBgn0003395.html gene 16-Dec-15 2015_12 "male sterile,visible,viable,male,reduced" macrochaeta FBgn0033886 Rpn13 Regulatory particle non-ATPase 13 http://flybase.net/reports/FBgn0033886.html protein_coding_gene "0043130=ubiquitin binding, 0061133=endopeptidase activator activity" "0046331=lateral inhibition, 0006511=ubiquitin-dependent protein catabolic process, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0043248=proteasome assembly" "0008541=proteasome regulatory particle, lid subcomplex, 0005838=proteasome regulatory particle, 0000502=proteasome complex, 0005737=cytoplasm, 0005634=nucleus" "GC13349, CG13349, p42E" "IPR006773=26S proteasome complex ubiquitin receptor, subunit Rpn13" CG13349 16-Dec-15 2015_12 ENSDARG00000058560(adrm1b) WBGene00016981(C56G2.7) ENSXETG00000002007(ADRM1) "ENSMUSG00000039041(Adrm1),ENSMUSG00000042165(Gm9774)" ENSG00000130706(ADRM1) "viable,visible,neuroanatomy defective" "chaeta,supernumerary,intersegmental nerve,anterior fascicle & synapse" FBgn0265537 CR44387 http://flybase.net/reports/FBgn0265537.html non_protein_coding_gene lincRNA.332 CR44387 16-Dec-15 2015_12 FBgn0262228 mir-975 mir-975 stem loop http://flybase.net/reports/FBgn0262228.html miRNA_gene "CR42935, miR-975" CR42935 16-Dec-15 2015_12 viable FBgn0016055 pir pirouette http://flybase.net/reports/FBgn0016055.html gene 16-Dec-15 2015_12 "viable,reduced,auditory perception defective,behavior defective" "optic lobe,photoreceptor cell,axon,ommatidium" FBgn0069081 sna::wor sna::wor http://flybase.net/reports/FBgn0069081.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0032335 CG14915 http://flybase.net/reports/FBgn0032335.html protein_coding_gene CG14915 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0261997 CG42815 http://flybase.net/reports/FBgn0261997.html "FBan0032186, FBgn0052186, FBgn0036753" protein_coding_gene "CG5944, CG32186, CG5587" CG42815 16-Dec-15 2015_12 "viable,fertile" FBgn0002219 l(3)67BDq lethal (3) 67BDq http://flybase.net/reports/FBgn0002219.html gene 16-Dec-15 2015_12 lethal FBgn0045861 cact::Hsap\NFKBIA NFKBIA http://flybase.net/reports/FBgn0045861.html engineered_fusion_gene 16-Dec-15 2015_12 wild-type FBgn0065715 l(2)SH0579 lethal (2) SH0579 http://flybase.net/reports/FBgn0065715.html gene l(2)SH2 0579 16-Dec-15 2015_12 "lethal,recessive" FBgn0263219 Dscam4 Down syndrome cell adhesion molecule 4 http://flybase.net/reports/FBgn0263219.html "FBgn0250795, FBgn0259232, FBgn0035862, FBgn0040831, FBgn0035864, FBgn0035863, FBgn0053274" protein_coding_gene 0042802=identical protein binding 0007155=cell adhesion 0005887=integral component of plasma membrane "CG33274, CG13672, CT21829, CG42330, CG18630, CG7060" "IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG42330 16-Dec-15 2015_12 "ENSDARG00000024865(dscam),ENSDARG00000028118(LOC565371),ENSDARG00000057052(LOC100002762)" ENSXETG00000003741(DSCAML1) "ENSMUSG00000050272(Dscam),ENSMUSG00000032087(Dscaml1)" "ENSG00000171587(DSCAM),ENSG00000177103(DSCAML1)" FBgn0267586 CR45924 http://flybase.net/reports/FBgn0267586.html non_protein_coding_gene CR45924 16-Dec-15 2015_12 FBgn0085321 CG34292 http://flybase.net/reports/FBgn0085321.html protein_coding_gene CG34292 16-Dec-15 2015_12 FBgn0002827 ms(2)E6 male sterile (2) E6 http://flybase.net/reports/FBgn0002827.html gene "ms2.6, ms(2)2.6" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0260858 Ykt6 YKT6 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0260858.html "FBgn0044802, FBgn0026664, FBgn0029978" protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0005484=SNAP receptor activity" "0016192=vesicle-mediated transport, 0006888=ER to Golgi vesicle-mediated transport, 0006890=retrograde vesicle-mediated transport, Golgi to ER" "0030133=transport vesicle, 0005768=endosome, 0016021=integral component of membrane, 0005794=Golgi apparatus, 0031201=SNARE complex" "Ykt6, Ykt6p, CG1515, l(1)G0155, YKT6, lethal (1) G0155, cg1515" "IPR010908=Longin domain, IPR011012=Longin-like domain, IPR001388=Synaptobrevin" CG1515 16-Dec-15 2015_12 ENSDARG00000038308(zgc:55536) YKL196C(YKT6) WBGene00015164(ykt-6) ENSXETG00000019002(ykt6) ENSMUSG00000002741(Ykt6) ENSG00000106636(YKT6) FBgn0026166 su(rdgB)82 su(rdgB)82 http://flybase.net/reports/FBgn0026166.html gene 16-Dec-15 2015_12 FBgn0033344 CG8252 http://flybase.net/reports/FBgn0033344.html protein_coding_gene IPR025663=A-kinase anchor protein 28kDa CG8252 16-Dec-15 2015_12 FBgn0002318 l(3)85Eb lethal (3) 85Eb http://flybase.net/reports/FBgn0002318.html gene "l(3)SG35, l(3)J5" 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0002263 l(3)69Ab lethal (3) 69Ab http://flybase.net/reports/FBgn0002263.html gene "rsg25, l(3)rsg25, rose-gespleten region interval 25" 16-Dec-15 2015_12 lethal FBgn0259343 C7 http://flybase.net/reports/FBgn0259343.html gene 16-Dec-15 2015_12 "visible,lethal" "wing vein,wing hair" FBgn0014876 Pt9 Protein 9 http://flybase.net/reports/FBgn0014876.html gene 16-Dec-15 2015_12 FBgn0004183 snRNA:U1:82Eb small nuclear RNA U1 at 82Eb http://flybase.net/reports/FBgn0004183.html "FBgn0003915, FBgn0003917" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005685=U1 snRNP "U1a-82Eb, U1-82Eb, U1snRNA82Eb, CR32862, U1snRNA, snRNA:U1, snRNA-U1-82.3, U1 snRNA, K5, chr3R:773643..773870, U1:82Eb, U1, snRNA:U1:82 Eb, small nuclear RNA U1, U1-82.3" CR32862 16-Dec-15 2015_12 FBgn0266146 CR44852 http://flybase.net/reports/FBgn0266146.html non_protein_coding_gene CR44852 16-Dec-15 2015_12 FBgn0035204 CG2277 http://flybase.net/reports/FBgn0035204.html protein_coding_gene 28575006 "IPR023214=HAD-like domain, IPR008380=HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase" CG2277 16-Dec-15 2015_12 ENSDARG00000006797(si:dkey-121j17.1) ENSXETG00000006163(NT5DC1) ENSMUSG00000039480(Nt5dc1) ENSG00000178425(NT5DC1) viable FBgn0042186 CG17239 http://flybase.net/reports/FBgn0042186.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP138 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG17239 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" FBgn0034195 Spn53F Serpin 53F http://flybase.net/reports/FBgn0034195.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space CG10956 "IPR023796=Serpin domain, IPR000215=Serpin family" CG10956 16-Dec-15 2015_12 viable FBgn0069103 mus321 mutagen-sensitive 321 http://flybase.net/reports/FBgn0069103.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0265913 CR44702 http://flybase.net/reports/FBgn0265913.html non_protein_coding_gene lincRNA.554 CR44702 16-Dec-15 2015_12 FBgn0000203 bod bowed http://flybase.net/reports/FBgn0000203.html gene 16-Dec-15 2015_12 "visible,recessive" "wing,eye" FBgn0261879 Z2-3941 http://flybase.net/reports/FBgn0261879.html gene 0030431=sleep 16-Dec-15 2015_12 behavior defective FBgn0065076 snoRNA:185 snoRNA:185 http://flybase.net/reports/FBgn0065076.html FBgn0053930 snoRNA_gene 0005730=nucleolus "snoR185, Dm-185, CR33930, DmOr_cd5(SnoR185)" CR33930 16-Dec-15 2015_12 FBgn0013509 l(1)Uc-1 lethal (1) Uc-1 http://flybase.net/reports/FBgn0013509.html gene 16-Dec-15 2015_12 lethal FBgn0002484 l(3)SG43 lethal (3) SG43 http://flybase.net/reports/FBgn0002484.html FBgn0005204 gene "7m63, l(3)A10, l(3)dsl10, l(3)dsl-10" 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0023070 l(1)20Ag lethal (1) 20Ag http://flybase.net/reports/FBgn0023070.html gene B2/45.8 16-Dec-15 2015_12 "lethal,recessive" FBgn0002289 l(3)73Cd lethal (3) 73Cd http://flybase.net/reports/FBgn0002289.html gene l(3)73CD 16-Dec-15 2015_12 lethal tergite FBgn0038928 Fadd Fas-associated death domain ortholog http://flybase.net/reports/FBgn0038928.html protein_coding_gene "0050700=CARD domain binding, 0005515=protein binding, 0005123=death receptor binding" "0007291=sperm individualization, 0007165=signal transduction, 0006915=apoptotic process, 0006955=immune response, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0002230=positive regulation of defense response to virus by host, 0006952=defense response, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0061057=peptidoglycan recognition protein signaling pathway" 0005737=cytoplasm "dFADD, CG12297, BG4_DROME, BG4, Fadd, Fas-associated death domain, dfadd, FADD, dFadd, fadd" "IPR011029=Death-like domain, IPR000488=Death domain" CG12297 16-Dec-15 2015_12 "viable,fertile,immune response defective,recessive,wild-type" spermatid FBgn0263249 CG43392 http://flybase.net/reports/FBgn0263249.html protein_coding_gene CG43392 16-Dec-15 2015_12 FBgn0034599 hng1 hinge1 http://flybase.net/reports/FBgn0034599.html protein_coding_gene 0003677=DNA binding "Hinge1, CG9437" "IPR004210=BESS motif, IPR006578=MADF domain" CG9437 16-Dec-15 2015_12 ENSDARG00000071733 "visible,size defective,flightless" "wing hinge,wing blade,distal" FBgn0263087 CG43355 http://flybase.net/reports/FBgn0263087.html protein_coding_gene chr2L:11486634..11486740 CG43355 16-Dec-15 2015_12 FBgn0263399 CG43445 http://flybase.net/reports/FBgn0263399.html protein_coding_gene CG43445 16-Dec-15 2015_12 FBgn0022207 l(2)k04222b lethal (2) k04222b http://flybase.net/reports/FBgn0022207.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052521 CG32521 http://flybase.net/reports/FBgn0052521.html "FBgn0031165, FBgn0031166" protein_coding_gene "CG1726, CG1735" CG32521 16-Dec-15 2015_12 "viable,fertile,visible,lethal - all die before end of pupal stage,some die during pupal stage" eye DRSC20550 I 0.021676317 -2.297563827 0.534901343 -0.400981107 -0.189883549 0.16270183 FBgn0029753 CG4198 http://flybase.net/reports/FBgn0029753.html protein_coding_gene CG4198 16-Dec-15 2015_12 lethal FBgn0027994 l(3)S126014 lethal (3) S126014 http://flybase.net/reports/FBgn0027994.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037477 CG14610 http://flybase.net/reports/FBgn0037477.html protein_coding_gene CG14610 16-Dec-15 2015_12 viable FBgn0283442 vas vasa http://flybase.net/reports/FBgn0283442.html "FBgn0262526, FBgn0003970, FBgn0004805, FBgn0283441" protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0005515=protein binding, 0008026=ATP-dependent helicase activity, 0003724=RNA helicase activity, 0003723=RNA binding, 0003730=mRNA 3'-UTR binding" "0008298=intracellular mRNA localization, 0006417=regulation of translation, 0030717=karyosome formation, 0007294=germarium-derived oocyte fate determination, 0007316=pole plasm RNA localization, 0048134=germ-line cyst formation, 0046011=regulation of oskar mRNA translation, 0007076=mitotic chromosome condensation, 0045727=positive regulation of translation, 0046012=positive regulation of oskar mRNA translation, 0007293=germarium-derived egg chamber formation, 0046843=dorsal appendage formation, 0007314=oocyte anterior/posterior axis specification, 0006378=mRNA polyadenylation, 0007315=pole plasm assembly, 0048477=oogenesis, 0008104=protein localization, 0007278=pole cell fate determination" "0043186=P granule, 0045170=spectrosome, 0045495=pole plasm, 0005737=cytoplasm, 0036464=cytoplasmic ribonucleoprotein granule, 0048471=perinuclear region of cytoplasm" "no-relish, BG:DS00929.14, VASA, fs(2)ltoRJ36, vasa, DmRH25, EP(2)0812, courgette, cgt, CG3506, female sterile(2)ltoRJ36, Vas, vas, VAS, unnamed, CG43081, CG46283, Vasa" "IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG46283 16-Dec-15 2015_12 "lethal,maternal effect,grandchildless,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,female semi-sterile,male sterile,heat sensitive,non-enhancer of variegation,non-suppressor of variegation,sterile,partially,mitotic cell cycle defective,female,wild-type" "dorsal appendage,karyosome,pole granule,maternal effect,pole cell,embryonic abdominal segment,pole plasm,egg,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,embryonic/larval salivary gland,micropyle,egg chamber,oocyte,ovary,follicle cell,P granule,spermatocyte,abdominal segment,ectopic,chorion | maternal effect,germline cyst,female germline stem cell,cystocyte,germarium region 1,nurse cell,oocyte nucleus,stage S6 oocyte,stage S9 oocyte,stage S10 oocyte,synaptonemal complex,cystoblast" FBgn0040372 G9a G9a http://flybase.net/reports/FBgn0040372.html FBgn0029516 protein_coding_gene "0018024=histone-lysine N-methyltransferase activity, 0008270=zinc ion binding" "1900111=positive regulation of histone H3-K9 dimethylation, 0002165=instar larval or pupal development, 0007616=long-term memory, 0010468=regulation of gene expression, 0050688=regulation of defense response to virus, 0051567=histone H3-K9 methylation, 0035076=ecdysone receptor-mediated signaling pathway, 0046959=habituation, 0050775=positive regulation of dendrite morphogenesis, 0008345=larval locomotory behavior, 0035220=wing disc development, 0007614=short-term memory" "0000791=euchromatin, 0005705=polytene chromosome interband, 0005634=nucleus" "dG9a, euchromatin histone methyltransferase, G9a, EG:BACR37P7.2, CG2995, EHMT, cab65850 G9a Dm, histone methyltransferase" "IPR003606=Pre-SET zinc-binding sub-group, IPR001214=SET domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR007728=Pre-SET domain" CG2995 16-Dec-15 2015_12 ENSDARG00000068157(ehmt1a) ENSXETG00000016933(EHMT1) "ENSMUSG00000036893(Ehmt1),ENSMUSG00000013787(Ehmt2)" "ENSG00000137324,ENSG00000204371(EHMT2),ENSG00000206376,ENSG00000181090(EHMT1)" "memory defective,viable,neuroanatomy defective,locomotor behavior defective,learning defective,fertile,non-suppressor of variegation,developmental rate defective,lethal - all die before end of P-stage,some die during pharate adult stage,visible,melanotic mass phenotype,lethal - all die before end of larval stage,some die during third instar larval stage" "ventral multidendritic neuron,multidendritic dendrite,wing vein,puparial operculum,wing" FBgn0065480 l(2)SH1284 lethal (2) SH1284 http://flybase.net/reports/FBgn0065480.html gene l(2)SH2 1284 16-Dec-15 2015_12 "lethal,recessive" FBgn0267723 CR46056 http://flybase.net/reports/FBgn0267723.html non_protein_coding_gene CR46056 16-Dec-15 2015_12 FBgn0038967 CG13847 http://flybase.net/reports/FBgn0038967.html protein_coding_gene CG13847 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" DRSC23172 K -1.104585369 -0.724132648 -0.7416529 -0.459395922 -0.734676971 2.531774788 FBgn0267550 CR45890 http://flybase.net/reports/FBgn0267550.html non_protein_coding_gene CR45890 16-Dec-15 2015_12 FBgn0039985 CG17474 http://flybase.net/reports/FBgn0039985.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035802 CG33275 http://flybase.net/reports/FBgn0035802.html "FBgn0035801, FBgn0035803, FBgn0035804, FBgn0053167, FBgn0053275" protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0005089=Rho guanyl-nucleotide exchange factor activity" "0035025=positive regulation of Rho protein signal transduction, 0007480=imaginal disc-derived leg morphogenesis" "CG7513, CG33167, CG7515, CG7520, CG7511" "IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG33275 16-Dec-15 2015_12 WBGene00009337(uig-1) ENSXETG00000008088() "ENSG00000153404(PLEKHG4B),ENSG00000196155(PLEKHG4)" "viable,fertile" FBgn0037936 CG6908 http://flybase.net/reports/FBgn0037936.html protein_coding_gene 0055070=copper ion homeostasis "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG6908 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0011403 l(3)j7C3 lethal (3) j7C3 http://flybase.net/reports/FBgn0011403.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001175 hap hapless http://flybase.net/reports/FBgn0001175.html gene "0007443=Malpighian tubule morphogenesis, 0001700=embryonic development via the syncytial blastoderm" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0066116 Fol2 Follistatin-related 2 http://flybase.net/reports/FBgn0066116.html gene "Follistatin 2, dFol2" 16-Dec-15 2015_12 FBgn0051151 wge winged eye http://flybase.net/reports/FBgn0051151.html "FBgn0039011, FBgn0039012" protein_coding_gene 0003682=chromatin binding "0030154=cell differentiation, 0007560=imaginal disc morphogenesis" 0000785=chromatin "CG4902, CG17621, CG31151" "IPR001025=Bromo adjacent homology (BAH) domain, IPR029616=Protein winged eye" CG31151 16-Dec-15 2015_12 ENSXETG00000015028(BAHCC1) ENSMUSG00000039741 ENSG00000182095(TNRC18) FBgn0001454 l(1)7Dh lethal (1) 7Dh http://flybase.net/reports/FBgn0001454.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065859 l(2)SH0285 lethal (2) SH0285 http://flybase.net/reports/FBgn0065859.html gene l(2)SH2 0285 16-Dec-15 2015_12 "lethal,recessive" FBgn0004153 l(2)57Ag lethal (2) 57Ag http://flybase.net/reports/FBgn0004153.html gene 16-Dec-15 2015_12 lethal FBgn0002533 Lcp2 Larval cuticle protein 2 http://flybase.net/reports/FBgn0002533.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0008363=larval chitin-based cuticle development, 0040003=chitin-based cuticle development" 0031012=extracellular matrix "CP2, DmelLcp2, LCP2, Gene II, L[[3]]CP2, lcp2, CG8697, 2, cuticle p. II, LCP-2, II" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG8697 16-Dec-15 2015_12 " larval stage | late third instar larval stage , larval stage | third instar stage 2 " " organism

, integumentary system

" "electrophoretic variant,viable" FBgn0060719 l(3)S068802 lethal (3) S068802 http://flybase.net/reports/FBgn0060719.html gene 0688/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0030834 CG8675 http://flybase.net/reports/FBgn0030834.html protein_coding_gene IPR019351=Protein of unknown function DUF2039 CG8675 16-Dec-15 2015_12 ENSDARG00000035570(zgc:101016) ENSXETG00000014376(C9orf85) ENSMUSG00000035171(1110059E24Rik) viable FBgn0003399 shr shrunken http://flybase.net/reports/FBgn0003399.html gene 16-Dec-15 2015_12 "viable,fertile,small body,body color defective" FBgn0069946 CG41089 http://flybase.net/reports/FBgn0069946.html FBan0041089 protein_coding_gene 16-Dec-15 2015_12 FBgn0015998 l(3)12E7 lethal (3) 12E7 http://flybase.net/reports/FBgn0015998.html gene 16-Dec-15 2015_12 lethal FBgn0037675 HP1e Heterochromatin Protein 1e http://flybase.net/reports/FBgn0037675.html protein_coding_gene 0003682=chromatin binding "0031940=positive regulation of chromatin silencing at telomere, 0051276=chromosome organization" "0005634=nucleus, 0000785=chromatin" "HP1e, HP1E, CG8120" "IPR008251=Chromo shadow domain, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR023779=Chromo domain, conserved site, IPR023780=Chromo domain" CG8120 16-Dec-15 2015_12 viable FBgn0010031 E(Dl)KP254 Enhancer of Delta KP254 http://flybase.net/reports/FBgn0010031.html gene 16-Dec-15 2015_12 FBgn0035782 CG14835 http://flybase.net/reports/FBgn0035782.html protein_coding_gene CG14835 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0061356 CG18003 http://flybase.net/reports/FBgn0061356.html "FBgn0033565, FBgn0050019, FBtr0088229, FBpp0087324, FBtr0088230, FBpp0087325, FBtr0088231, FBpp0087326" protein_coding_gene "0010181=FMN binding, 0008891=glycolate oxidase activity" 0055114=oxidation-reduction process 0005777=peroxisome CG30019 "IPR008259=FMN-dependent alpha-hydroxy acid dehydrogenase, active site, IPR013785=Aldolase-type TIM barrel, IPR000262=FMN-dependent dehydrogenase, IPR012133=Alpha-hydroxy acid dehydrogenase, FMN-dependent" CG18003 16-Dec-15 2015_12 "ENSDARG00000027992(hao2),ENSDARG00000067753" YML054C(CYB2) WBGene00018286(F41E6.5) "ENSXETG00000018082(Q5BKF6_XENTR),ENSXETG00000005520(HAO1)" ENSMUSG00000027261(Hao1) ENSG00000101323(HAO1) "viable,fertile" FBgn0013704 mt:tRNA:R mitochondrial arginine tRNA http://flybase.net/reports/FBgn0013704.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006303, tRNA[Arg], Arg-maxi, CR34078" CR34078 16-Dec-15 2015_12 FBgn0011580 Dlw Dorsal wing http://flybase.net/reports/FBgn0011580.html gene 0048190=wing disc dorsal/ventral pattern formation 16-Dec-15 2015_12 "lethal,recessive,visible,somatic clone,dominant,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone,mesothoracic tergum & macrochaeta | somatic clone,macrochaeta,dorsal,ventral compartment" FBgn0051112 CG31112 http://flybase.net/reports/FBgn0051112.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025344 anon-17Ac anon-17Ac http://flybase.net/reports/FBgn0025344.html gene unnamed 16-Dec-15 2015_12 FBgn0061152 l(2)J73 lethal (2) J73 http://flybase.net/reports/FBgn0061152.html gene J73 16-Dec-15 2015_12 "lethal,recessive" FBgn0262205 mir-932 mir-932 stem loop http://flybase.net/reports/FBgn0262205.html miRNA_gene 0008589=regulation of smoothened signaling pathway "dme-miR-932, dme-mir-932, CR42912, miR-932" CR42912 16-Dec-15 2015_12 "lethal,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "eye,wing,wing blade" FBgn0065386 l(2)SH1636 lethal (2) SH1636 http://flybase.net/reports/FBgn0065386.html gene l(2)SH2 1636 16-Dec-15 2015_12 "lethal,recessive" FBgn0261921 CG8176::EndoA http://flybase.net/reports/FBgn0261921.html engineered_fusion_gene CG8176::endoA 16-Dec-15 2015_12 FBgn0030170 CG2990 http://flybase.net/reports/FBgn0030170.html protein_coding_gene "0004003=ATP-dependent DNA helicase activity, 0000014=single-stranded DNA endodeoxyribonuclease activity, 0043142=single-stranded DNA-dependent ATPase activity, 0017108=5'-flap endonuclease activity" "0033567=DNA replication, Okazaki fragment processing" "IPR026851=Dna2, IPR014808=DNA replication factor Dna2, N-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG2990 16-Dec-15 2015_12 YHR164C(DNA2) WBGene00001016(dna-2) ENSXETG00000007483(DNA2) ENSMUSG00000036875(Dna2) ENSG00000138346(DNA2) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0063417 l(3)3450-F lethal (3) 3450-F http://flybase.net/reports/FBgn0063417.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267138 CR45578 http://flybase.net/reports/FBgn0267138.html non_protein_coding_gene CR45578 16-Dec-15 2015_12 FBgn0066111 su(f)::Hsap\CSTF3 CSTF3 http://flybase.net/reports/FBgn0066111.html engineered_fusion_gene Hsap\CSTF3::su(f) 16-Dec-15 2015_12 FBgn0260119 2L4117 http://flybase.net/reports/FBgn0260119.html gene "0035149=lumen formation, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0026638 l(2)k11006 lethal (2) k11006 http://flybase.net/reports/FBgn0026638.html gene 16-Dec-15 2015_12 FBgn0266863 CR45324 http://flybase.net/reports/FBgn0266863.html non_protein_coding_gene CR45324 16-Dec-15 2015_12 FBgn0085791 CR41508 http://flybase.net/reports/FBgn0085791.html FBan0041508 pseudogene_attribute CR41508 16-Dec-15 2015_12 FBgn0042118 Cpr65Ax2 Cuticular protein 65Ax2 http://flybase.net/reports/FBgn0042118.html FBgn0047080 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG18777, BcDNA:RE62456, DmelCpr65Ax2" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG18777 16-Dec-15 2015_12 FBgn0039743 CG7946 http://flybase.net/reports/FBgn0039743.html protein_coding_gene "IPR000313=PWWP domain, IPR021567=Lens epithelium-derived growth factor (LEDGF)" CG7946 16-Dec-15 2015_12 "ENSXETG00000018516(TGas123j17.1-001),ENSXETG00000016086()" "ENSMUSG00000002833(Hdgfrp2),ENSMUSG00000028484(Psip1)" "ENSG00000164985(PSIP1),ENSG00000167674(HDGFRP2)" "viable,female fertile" FBgn0038353 CG5399 http://flybase.net/reports/FBgn0038353.html protein_coding_gene IPR011038=Calycin-like CG5399 16-Dec-15 2015_12 DRSC15791 I 2.077510487 -1.682918453 0.784730096 -0.45022926 -0.423011268 -0.362055339 FBgn0037338 Snm1 Snm1 http://flybase.net/reports/FBgn0037338.html protein_coding_gene 0006281=DNA repair "SNM1, mutagen-sensitive 322, CG10018, mus322" "IPR001279=Metallo-beta-lactamase, IPR011084=DNA repair metallo-beta-lactamase" CG10018 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0050160 CG30160 http://flybase.net/reports/FBgn0050160.html protein_coding_gene 0016021=integral component of membrane "IPR000301=Tetraspanin, IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG30160 16-Dec-15 2015_12 DRSC04961 I 1.646148338 0.310735068 1.031219393 -0.517580823 0.2887113 -1.347242236 FBgn0266167 CR44873 http://flybase.net/reports/FBgn0266167.html non_protein_coding_gene CR44873 16-Dec-15 2015_12 FBgn0065621 l(2)SH0804 lethal (2) SH0804 http://flybase.net/reports/FBgn0065621.html gene l(2)SH2 0804 16-Dec-15 2015_12 "lethal,recessive" FBgn0005496 l(1)tsSD19 lethal (1) tsSD19 http://flybase.net/reports/FBgn0005496.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0085436 Not1 Not1 http://flybase.net/reports/FBgn0085436.html "FBgn0033424, FBgn0033425, FBgn0026000, FBgn0062162" protein_coding_gene 0005515=protein binding "0007095=mitotic G2 DNA damage checkpoint, 0007517=muscle organ development, 0006402=mRNA catabolic process, 0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0048813=dendrite morphogenesis, 0017148=negative regulation of translation, 0022008=neurogenesis" "0030014=CCR4-NOT complex, 0005737=cytoplasm" "not1, anon-WO0118547.221, unnamed, CG1874, NOT, CG34407, NOT1, anon-EST:Liang-1.29, CG1884, clone 1.29" "IPR007196=CCR4-Not complex component, Not1, C-terminal, IPR024557=CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819" CG34407 16-Dec-15 2015_12 ENSDARG00000004174(cnot1) YCR093W(CDC39) WBGene00002845(let-711) ENSXETG00000015900(CNOT1) ENSMUSG00000036550(Cnot1) ENSG00000125107(CNOT1) "visible,lethal,neuroanatomy defective" "wing vein,ectopic,wing,eye,embryonic/larval neuroblast,ganglion mother cell" DRSC06787 IEK 1.611823337 -1.971264058 -3.275680596 -4.408509334 2.656337605 2.313634322 FBgn0039697 CG7834 http://flybase.net/reports/FBgn0039697.html protein_coding_gene 0009055=electron carrier activity "0006119=oxidative phosphorylation, 0007406=negative regulation of neuroblast proliferation" "0017133=mitochondrial electron transfer flavoprotein complex, 0005875=microtubule associated complex, 0005811=lipid particle, 0005739=mitochondrion" "ETFB, Electron transfer flavoprotein beta subunit, Electron transfer flavoprotein beta-subunit, electron transfer flavoprotein beta subunit, CG 7834" "IPR014730=Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, IPR000049=Electron transfer flavoprotein, beta-subunit, conserved site, IPR012255=Electron transfer flavoprotein, beta subunit, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG7834 16-Dec-15 2015_12 ENSDARG00000009250(etfb) YGR207C() WBGene00017734(F23C8.5) ENSXETG00000022222(etfb) ENSMUSG00000004610(Etfb) ENSG00000105379(ETFB) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0043993 Su(rst)D231 Su(rst)D231 http://flybase.net/reports/FBgn0043993.html gene 0001745=compound eye morphogenesis D231 16-Dec-15 2015_12 viable FBgn0051716 Cnot4 Cnot 4 homologue http://flybase.net/reports/FBgn0051716.html "FBgn0032238, FBgn0032239" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0008270=zinc ion binding, 0003676=nucleic acid binding, 0004842=ubiquitin-protein transferase activity" "0046425=regulation of JAK-STAT cascade, 0045892=negative regulation of transcription, DNA-templated, 0051297=centrosome organization, 0016567=protein ubiquitination" 0005737=cytoplasm "CG31716, CG5244, CG5251, NOT4, not4, cg5251, Not4, Q8IPB9_DROME, Cont4" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000571=Zinc finger, CCCH-type, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain, IPR001841=Zinc finger, RING-type" CG31716 16-Dec-15 2015_12 "ENSDARG00000007639(zgc:63566),ENSDARG00000007045(LOC569055)" YER068W(MOT2) WBGene00003827(ntl-4) ENSXETG00000010594(cnot4) ENSMUSG00000038784(Cnot4) ENSG00000080802(CNOT4) "viable,fertile" DRSC02831 K 0.508440888 -0.254914402 0.258938133 0.152073587 2.710025203 1.194609827 FBgn0051892 tRNA:CR31892 transfer RNA:CR31892 http://flybase.net/reports/FBgn0051892.html "FBgn0011842, FBgn0060259" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033458=GAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:asp2:29D, tRNA:D:GTC:AE002690-f, AE002690.trna22-AspGTC, tRNA:D2:29D, tRNA:asp2:29D, chr2L.trna32-AspGTC, tRNA[Asp-GTC], CR31892, tRNA[[Asp]]" CR31892 16-Dec-15 2015_12 FBgn0001505 l(1)10Dc lethal (1) 10Dc http://flybase.net/reports/FBgn0001505.html gene 16-Dec-15 2015_12 lethal FBgn0011672 Mvl Malvolio http://flybase.net/reports/FBgn0011672.html protein_coding_gene "0015293=symporter activity, 0005381=iron ion transmembrane transporter activity, 0005375=copper ion transmembrane transporter activity, 0005384=manganese ion transmembrane transporter activity" "0015677=copper ion import, 0046718=viral entry into host cell, 0070838=divalent metal ion transport, 0033212=iron assimilation, 0055076=transition metal ion homeostasis, 0050916=sensory perception of sweet taste, 0034761=positive regulation of iron ion transmembrane transport, 0060586=multicellular organismal iron ion homeostasis, 0000041=transition metal ion transport, 0055070=copper ion homeostasis" "0016020=membrane, 0005886=plasma membrane, 0005768=endosome, 0005887=integral component of plasma membrane" "DMT1, CG3671, /Divalent metal transporter, dNRAMP, malvolio, mvl, NRM2" IPR001046=NRAMP family CG3671 16-Dec-15 2015_12 "YOL122C(SMF1),YHR050W(SMF2),YLR034C(SMF3)" "WBGene00004876(smf-1),WBGene00004877(smf-2),WBGene00004878(smf-3)" "ENSXETG00000009636(SLC11A2),ENSXETG00000014937(SLC11A1)" "ENSMUSG00000023030(Slc11a2),ENSMUSG00000026177(Slc11a1)" "ENSG00000110911(SLC11A2),ENSG00000018280(SLC11A1)" " embryonic stage | stage 16 , embryonic stage -- adult stage , embryonic stage | stage 10 " " antenno-maxillary complex

, procephalic segment

, tracheal pit | vicinity

, amnioserosa

" "lethal,recessive,behavior defective,semidominant,taste perception defective,conditional,partially lethal - majority die,female limited,chemical sensitive,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0264696 CG43965 http://flybase.net/reports/FBgn0264696.html protein_coding_gene CG43965 16-Dec-15 2015_12 FBgn0032018 CG7806 http://flybase.net/reports/FBgn0032018.html protein_coding_gene "0008559=xenobiotic-transporting ATPase activity, 0005524=ATP binding" 0055085=transmembrane transport 0016021=integral component of membrane Dme_CG7806 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG7806 16-Dec-15 2015_12 ENSXETG00000010586(ABCC10) ENSMUSG00000032842(Abcc10) ENSG00000124574(ABCC10) "viable,fertile" FBgn0003034 SP Sex Peptide http://flybase.net/reports/FBgn0003034.html FBgn0010084 protein_coding_gene "0005179=hormone activity, 0001664=G-protein coupled receptor binding, 0005515=protein binding" "0045297=post-mating behavior, 0046662=regulation of oviposition, 0048042=regulation of post-mating oviposition, 0045434=negative regulation of female receptivity, post-mating, 0006718=juvenile hormone biosynthetic process, 0007186=G-protein coupled receptor signaling pathway, 0032504=multicellular organism reproduction, 0048477=oogenesis, 0007621=negative regulation of female receptivity, 0046008=regulation of female receptivity, post-mating, 0018991=oviposition, 0008343=adult feeding behavior, 0007557=regulation of juvenile hormone biosynthetic process" "0005576=extracellular region, 0005615=extracellular space" "Acp70, SP, Paragonial-peptide-B, DrmSP, Sex-Peptide, Sex peptide, Acp70a, ACP, Acp70A, sex-peptide, Accessory gland peptide 70A, Spg70, Accessory gland protein 70A, CG17673, Acp-70A, sex peptide, accessory protein 70A, sexpeptide, sex peptide gene in 70, Sex-peptide, ACP70A, Sex Peptide, Apc70A, PapB" IPR012608=Sex peptide CG17673 16-Dec-15 2015_12 "mating behavior defective,virgin female limited,lethal,female,courtship behavior defective,feeding behavior defective,female limited,behavior defective,mated female limited" spermatozoon FBgn0063409 l(3)3450-N lethal (3) 3450-N http://flybase.net/reports/FBgn0063409.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040748 CG13943 http://flybase.net/reports/FBgn0040748.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014171 fs(3)83Ba fs(3)83Ba http://flybase.net/reports/FBgn0014171.html gene unnamed 16-Dec-15 2015_12 female sterile "dorsal appendage,nurse cell,egg" FBgn0004199 l(3)84Da lethal (3) 84Da http://flybase.net/reports/FBgn0004199.html gene 16-Dec-15 2015_12 lethal FBgn0039280 Mocs2 Molybdenum cofactor synthesis 2 http://flybase.net/reports/FBgn0039280.html protein_coding_gene "0004402=histone acetyltransferase activity, 0030366=molybdopterin synthase activity" "0016573=histone acetylation, 0006338=chromatin remodeling, 0006777=Mo-molybdopterin cofactor biosynthetic process" "0005829=cytosol, 0019008=molybdopterin synthase complex, 0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0005700=polytene chromosome" "MBIP/dMoaE, MOCS2, CG10238, Molybdopterin synthase 2, dMoaE, molybdopterin synthase 2, Dromel_CG10238_FBtr0084782_mocs_mORF, Mbip, MAPK upstream kinase-binding inhibitory protein, MUK-binding inhibitory protein" "IPR016155=Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp, IPR012675=Beta-grasp domain, IPR010034=Molybdopterin converting factor, subunit 1, IPR003749=ThiamineS/Molybdopterin converting factor subunit 1, IPR028887=Molybdopterin synthase sulfur carrier subunit" CG10238 16-Dec-15 2015_12 ENSDARG00000019364(mbip) ENSXETG00000002911(MBIP) ENSMUSG00000021028(Mbip) ENSG00000151332(MBIP) viable FBgn0038236 Cyp313a1 Cyp313a1 http://flybase.net/reports/FBgn0038236.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0005506=iron ion binding" "0017143=insecticide metabolic process, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG3360, 313a1, 313a1p, Cyp313a, Cyp313A1, Cyp313a1p" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG3360 16-Dec-15 2015_12 YDR402C(DIT2) viable DRSC16624 K 0.185306243 0.776872943 0.332012511 0.214795089 -0.08819302 -1.625350741 FBgn0064164 l(3)S007631 lethal (3) S007631 http://flybase.net/reports/FBgn0064164.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0003576 Su(S) Suppressor of Star http://flybase.net/reports/FBgn0003576.html gene 16-Dec-15 2015_12 FBgn0066346 l(3)99DEi lethal (3) 99DEi http://flybase.net/reports/FBgn0066346.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004614 Adv Additional veins http://flybase.net/reports/FBgn0004614.html gene 0008586=imaginal disc-derived wing vein morphogenesis Additional vein 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "wing vein,wing vein L1,wing vein L3,wing vein L2,ectopic" FBgn0035237 CG13917 http://flybase.net/reports/FBgn0035237.html protein_coding_gene "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG13917 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0061146 l(3)S000122b lethal (3) S000122b http://flybase.net/reports/FBgn0061146.html gene 22-Jan 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031314 IntS14 Integrator 14 http://flybase.net/reports/FBgn0031314.html protein_coding_gene 0034472=snRNA 3'-end processing "0005634=nucleus, 0032039=integrator complex" "IntS14, Q9VPY0, CG4785" "IPR002035=von Willebrand factor, type A" CG4785 16-Dec-15 2015_12 ENSDARG00000041429(zgc:55794) ENSXETG00000006644(C15orf44) ENSMUSG00000034263(2010321M09Rik) ENSG00000138614(C15orf44) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035424 CG11505 http://flybase.net/reports/FBgn0035424.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006630=RNA-binding protein Lupus La, IPR000504=RNA recognition motif domain" CG11505 16-Dec-15 2015_12 ENSDARG00000062146(zgc:153918) WBGene00004147(larp-5) "ENSXETG00000007283(LARP4),ENSXETG00000016882(LARP4B)" "viable,fertile,lethal" FBgn0005419 l(1)adl8 lethal (1) adl8 http://flybase.net/reports/FBgn0005419.html gene l(1)adl-8 16-Dec-15 2015_12 "short lived,heat sensitive,partially lethal - majority die,lethal" FBgn0265613 CR44431 http://flybase.net/reports/FBgn0265613.html non_protein_coding_gene CR44431 16-Dec-15 2015_12 FBgn0086345 FGC026A04 http://flybase.net/reports/FBgn0086345.html nuclear_gene 16-Dec-15 2015_12 FBgn0032797 CG10186 http://flybase.net/reports/FBgn0032797.html FBgn0027734 protein_coding_gene 0030414=peptidase inhibitor activity "0005576=extracellular region, 0016020=membrane" "anon-EST:Posey189, CT28647" "IPR007110=Immunoglobulin-like domain, IPR000436=Sushi/SCR/CCP domain, IPR008197=WAP-type 'four-disulfide core' domain, IPR013783=Immunoglobulin-like fold" CG10186 16-Dec-15 2015_12 WBGene00009500(F36H2.3) ENSMUSG00000026616(Cr2) ENSG00000000971(CFH) viable FBgn0060572 l(3)S095812b lethal (3) S095812b http://flybase.net/reports/FBgn0060572.html gene 0958/12 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0031860 CG11236 http://flybase.net/reports/FBgn0031860.html protein_coding_gene "0008445=D-aspartate oxidase activity, 0071949=FAD binding" "0046416=D-amino acid metabolic process, 0055114=oxidation-reduction process" 0005777=peroxisome "IPR006181=D-amino acid oxidase, conserved site, IPR016040=NAD(P)-binding domain, IPR006076=FAD dependent oxidoreductase, IPR023209=D-amino-acid oxidase" CG11236 16-Dec-15 2015_12 "ENSDARG00000035603(dao.2),ENSDARG00000035602(dao.1),ENSDARG00000035601(dao.3)" WBGene00022076(daao-1) viable FBgn0020609 alf aloof http://flybase.net/reports/FBgn0020609.html gene "0007411=axon guidance, 0007413=axonal fasciculation, 0007399=nervous system development" 16-Dec-15 2015_12 "Bolwig organ,Bolwig nerve" FBgn0067782 att-ORFB alternative testis transcripts open reading frame B http://flybase.net/reports/FBgn0067782.html FBgn0019839 protein_coding_gene "att, alternative testis transcripts, unnamed, CG33488" CG33488 16-Dec-15 2015_12 FBgn0033950 CG12862 http://flybase.net/reports/FBgn0033950.html protein_coding_gene CG12862 16-Dec-15 2015_12 FBgn0266284 Ns3 Nucleostemin ortholog (H. sapiens) 3 http://flybase.net/reports/FBgn0266284.html "FBgn0028274, FBgn0027792, FBgn0001371" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0000054=ribosomal subunit export from nucleus, 0009267=cellular response to starvation, 0042254=ribosome biogenesis, 0040018=positive regulation of multicellular organism growth, 0051168=nuclear export" "0005829=cytosol, 0005737=cytoplasm, 0015030=Cajal body, 0005783=endoplasmic reticulum" "lethal (1) 2Ad, lethal (1) G0431, nucleostemin 3, A60, dNS3, CG14788, EG:BACN32G11.5, l(1)G0431, l(1)2Ad, ns3, dmNuc3, BACN32G11.5, l(1)BA11" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR023179=GTP-binding protein, orthogonal bundle domain, IPR030378=Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR006073=GTP binding domain" CG14788 16-Dec-15 2015_12 ENSDARG00000015352(zgc:76988) YGL099W(LSG1) WBGene00016907(C53H9.2) ENSXETG00000003451(TGas105m04.1) ENSMUSG00000022538(Lsg1) ENSG00000041802(LSG1) FBgn0019742 l(1)8e3-43 lethal (1) 8e3-43 http://flybase.net/reports/FBgn0019742.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010873 l(3)05697 lethal (3) 05697 http://flybase.net/reports/FBgn0010873.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025798 Su(var)1301 Suppressor of variegation 1301 http://flybase.net/reports/FBgn0025798.html gene Su-var(2) 16-Dec-15 2015_12 FBgn0015278 Pi3K68D Phosphotidylinositol 3 kinase 68D http://flybase.net/reports/FBgn0015278.html FBgn0047208 protein_coding_gene "0035005=1-phosphatidylinositol-4-phosphate 3-kinase activity, 0017137=Rab GTPase binding, 0035004=phosphatidylinositol 3-kinase activity, 0035091=phosphatidylinositol binding, 0046934=phosphatidylinositol-4,5-bisphosphate 3-kinase activity, 0005543=phospholipid binding, 0016303=1-phosphatidylinositol-3-kinase activity, 0005515=protein binding" "0048015=phosphatidylinositol-mediated signaling, 0006909=phagocytosis, 0030866=cortical actin cytoskeleton organization, 0006974=cellular response to DNA damage stimulus, 0046854=phosphatidylinositol phosphorylation" 0010008=endosome membrane "PI3K_68D, dPI3K, pi3k68d, dPIK, PI 3-kinase, dPI 3-kinase, PI(3)K, Cpk, PI3K-68D/E, PI3K 68_D, PI3K-68D, PI3K 68D, Pi3K, CG11621, PI3-kinase, BcDNA:LD15217, 11621, PI[[3]]K, PI3K68D, cpk, PI3K" "IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR016024=Armadillo-type fold, IPR000341=Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain, IPR015433=Phosphatidylinositol Kinase, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR011009=Protein kinase-like domain, IPR001263=Phosphoinositide 3-kinase, accessory (PIK) domain, IPR000008=C2 domain, IPR029071=Ubiquitin-related domain, IPR002420=Phosphatidylinositol 3-kinase, C2 domain, IPR001683=Phox homologous domain" CG11621 16-Dec-15 2015_12 "ENSDARG00000060841(si:dkey-24l11.7),ENSDARG00000070062(nox1)" WBGene00009552(piki-1) ENSXETG00000016008(PIK3C2A) "ENSMUSG00000026447(Pik3c2b),ENSMUSG00000030660(Pik3c2a)" "ENSG00000133056(PIK3C2B),ENSG00000011405(PIK3C2A)" larval stage--adult stage "visible,partially lethal - majority die,some die during pupal stage" "wing,scutellum,scutellar bristle,wing basal cell 1,proximal,haltere,wing vein,ectopic,wing margin,chaeta,supernumerary,sensillum campaniformium,embryonic/larval hemocyte,macrophage" FBgn0051087 CG31087 http://flybase.net/reports/FBgn0051087.html FBgn0039322 protein_coding_gene 0022008=neurogenesis CG10551 "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG31087 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell" DRSC14253 I 1.726659438 -0.110506557 0.093540046 0.225407553 -0.119012126 -0.005958847 FBgn0005475 l(1)ts1006 lethal (1) ts1006 http://flybase.net/reports/FBgn0005475.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0065085 snmRNA:705 small non-messenger RNA 705 http://flybase.net/reports/FBgn0065085.html non_protein_coding_gene Dm-705 16-Dec-15 2015_12 FBgn0086538 MRE6 mRNA-like ncRNA in embryogenesis 6 http://flybase.net/reports/FBgn0086538.html non_protein_coding_gene GM04458 16-Dec-15 2015_12 FBgn0266347 nAChRë±4 nicotinic Acetylcholine Receptor ë±4 http://flybase.net/reports/FBgn0266347.html "FBgn0041731, FBgn0037212, FBan0012414, FBgn0037211, FBgn0044798" protein_coding_gene "0015464=acetylcholine receptor activity, 0004889=acetylcholine-activated cation-selective channel activity" "0030431=sleep, 0006811=ion transport" "0005892=acetylcholine-gated channel complex, 0045211=postsynaptic membrane" "nAcRalpha-80, nAcRalpha-4, nAChR, nAcRalpha-80B, nicotinic Acetylcholine Receptor alpha 4, nicotinic Acetylcholine Receptor alpha 80B, redeye, CG17552, CG12414, nAChRalpha4, anon-WO0138359.1, rye, Dalpha4, nAcRaplha-80B" "IPR002394=Nicotinic acetylcholine receptor, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006201=Neurotransmitter-gated ion-channel, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain" CG12414 16-Dec-15 2015_12 "ENSDARG00000057025(chrna2b),ENSDARG00000006602(chrna2a),ENSDARG00000058393(chrna4),ENSDARG00000070724(LOC563696),ENSDARG00000057848,ENSDARG00000054497(LOC568467),ENSDARG00000055559(chrna6)" WBGene00006797(unc-63) ENSXETG00000017553(CHRNA2) "ENSMUSG00000032303(Chrna3),ENSMUSG00000031491(Chrna6),ENSMUSG00000027577(Chrna4),ENSMUSG00000022041(Chrna2)" "ENSG00000101204(CHRNA4),ENSG00000120903(CHRNA2),ENSG00000080644(CHRNA3),ENSG00000147434(CHRNA6)" FBgn0065737 l(2)SH0540 lethal (2) SH0540 http://flybase.net/reports/FBgn0065737.html gene l(2)SH2 0540 16-Dec-15 2015_12 "lethal,recessive" FBgn0052111 CR32111 http://flybase.net/reports/FBgn0052111.html non_protein_coding_gene CG32111 CR32111 16-Dec-15 2015_12 viable FBgn0002583 Rp7-8 Ribosomal protein 7/8 http://flybase.net/reports/FBgn0002583.html gene 0003735=structural constituent of ribosome 0006412=translation 0005840=ribosome "Minute(1)5D6A, M(1)5D6A, Rp7/8" 16-Dec-15 2015_12 FBgn0052851 CG32851 http://flybase.net/reports/FBgn0052851.html protein_coding_gene 0005615=extracellular space 16-Dec-15 2015_12 FBgn0266852 CR45313 http://flybase.net/reports/FBgn0266852.html non_protein_coding_gene CR45313 16-Dec-15 2015_12 FBgn0001683 l(1)ESHS4 lethal (1) ESHS4 http://flybase.net/reports/FBgn0001683.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030326 CG2444 http://flybase.net/reports/FBgn0030326.html FBgn0063134 protein_coding_gene 0005615=extracellular space "DIGF-6, BcDNA:LP01642" IPR029277=Single domain Von Willebrand factor type C domain CG2444 16-Dec-15 2015_12 FBgn0004477 l(1)air1 lethal aberrant immune response 1 http://flybase.net/reports/FBgn0004477.html gene "l(1)air[1], air1" 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,embryonic/larval lymph gland,melanotic mass" FBgn0267704 flam flamenco http://flybase.net/reports/FBgn0267704.html FBgn0005628 non_protein_coding_gene "0048477=oogenesis, 0008049=male courtship behavior, 0030707=ovarian follicle cell development" "flamenco cluster, lincRNA.1041, Flamingo, flamenco, piRNA cluster, CR46037" CR46037 16-Dec-15 2015_12 FBgn0266799 CR45261 http://flybase.net/reports/FBgn0266799.html non_protein_coding_gene CR45261 16-Dec-15 2015_12 FBgn0024210 miscue miscue http://flybase.net/reports/FBgn0024210.html gene 0007411=axon guidance 16-Dec-15 2015_12 FBgn0085285 CG34256 http://flybase.net/reports/FBgn0085285.html protein_coding_gene "IPR012674=Calycin, IPR011038=Calycin-like" CG34256 16-Dec-15 2015_12 FBgn0041616 SM3-6 SM3-6 http://flybase.net/reports/FBgn0041616.html gene 16-Dec-15 2015_12 FBgn0069235 gl(2L)137-8 gl(2L)137-8 http://flybase.net/reports/FBgn0069235.html gene 0009952=anterior/posterior pattern specification 16-Dec-15 2015_12 "lethal,recessive,germline clone,non-rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0039986 CG18257 http://flybase.net/reports/FBgn0039986.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264301 CG43779 http://flybase.net/reports/FBgn0264301.html FBgn0032502 protein_coding_gene CG15639 CG43779 16-Dec-15 2015_12 viable FBgn0263352 Unr Upstream of N-ras http://flybase.net/reports/FBgn0263352.html "FBgn0062463, FBgn0052028, FBgn0035895" protein_coding_gene "0003730=mRNA 3'-UTR binding, 0003677=DNA binding, 0003676=nucleic acid binding, 0005515=protein binding" "0009047=dosage compensation by hyperactivation of X chromosome, 0042714=dosage compensation complex assembly, 0046331=lateral inhibition, 0017148=negative regulation of translation, 0006355=regulation of transcription, DNA-templated, 0007549=dosage compensation" 0005737=cytoplasm "upstream of N-ras, MRE30, CR32028, UNR, Upstream of N-Ras, unr, CG7015, dUNR, BcDNA:LD13080" "IPR012340=Nucleic acid-binding, OB-fold, IPR019844=Cold-shock conserved site, IPR011129=Cold shock protein, IPR002059=Cold-shock protein, DNA-binding, IPR011989=Armadillo-like helical" CG7015 16-Dec-15 2015_12 ENSDARG00000062157(wu:fa92c07) ENSMUSG00000068823(Csde1) ENSG00000009307(CSDE1) FBgn0037584 CG7963 http://flybase.net/reports/FBgn0037584.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG7963 16-Dec-15 2015_12 viable FBgn0263478 snoRNA:Edc3-a http://flybase.net/reports/FBgn0263478.html snoRNA_gene CR43593 16-Dec-15 2015_12 FBgn0085417 natalisin natalisin http://flybase.net/reports/FBgn0085417.html "FBgn0038229, FBgn0038230" protein_coding_gene 0060179=male mating behavior "NTL, CG14843, CG34388, ntl, CG14842" CG34388 16-Dec-15 2015_12 "lethal,courtship behavior defective,male,grooming behavior defective,female,mating behavior defective" FBgn0262361 CG43059 http://flybase.net/reports/FBgn0262361.html protein_coding_gene CG43059 16-Dec-15 2015_12 FBgn0082938 snoRNA:Me28S-C2645a http://flybase.net/reports/FBgn0082938.html snoRNA_gene "Me28S-Cm2645a, Me28S-C2645a, snoRNA:Me28S-Cm2645a, DmSnR64, DmSnR64a, Me28S-C2645a(DmSnR64), CR34587, SnR64" CR34587 16-Dec-15 2015_12 FBgn0001053 fs(3)K1 female sterile (3) K1 http://flybase.net/reports/FBgn0001053.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "dorsal appendage,maternal effect" FBgn0260087 2L4333 http://flybase.net/reports/FBgn0260087.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0069961 CG41051 http://flybase.net/reports/FBgn0069961.html FBan0041051 protein_coding_gene 16-Dec-15 2015_12 FBgn0013650 ms(2)ry6 ms(2)ry6 http://flybase.net/reports/FBgn0013650.html gene "unnamed, ms(2)6" 16-Dec-15 2015_12 male sterile FBgn0011086 l(1)Q44 lethal (1) Q44 http://flybase.net/reports/FBgn0011086.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0030108 Gr8a Gustatory receptor 8a http://flybase.net/reports/FBgn0030108.html protein_coding_gene 0008527=taste receptor activity "0017085=response to insecticide, 0007635=chemosensory behavior, 0050909=sensory perception of taste" 0016021=integral component of membrane "GR8a, Gr8D1, Gustatory receptor 8D1, CG15371" IPR013604=7TM chemoreceptor CG15371 16-Dec-15 2015_12 "viable,fertile,chemosensitive behavior defective,neurophysiology defective" "S-type sensilla S3,S-type sensilla S5,S-type sensilla S10" FBgn0262944 CR43263 http://flybase.net/reports/FBgn0262944.html non_protein_coding_gene CR43263 16-Dec-15 2015_12 FBgn0026677 l(1)G0105 lethal (1) G0105 http://flybase.net/reports/FBgn0026677.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033222 CG12824 http://flybase.net/reports/FBgn0033222.html protein_coding_gene CG12824 16-Dec-15 2015_12 FBgn0266869 CR45330 http://flybase.net/reports/FBgn0266869.html non_protein_coding_gene CR45330 16-Dec-15 2015_12 FBgn0263092 CR43360 http://flybase.net/reports/FBgn0263092.html pseudogene_attribute CR43360 16-Dec-15 2015_12 FBgn0027955 l(3)j6E3 lethal (3) j6E3 http://flybase.net/reports/FBgn0027955.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036139 CG6216 http://flybase.net/reports/FBgn0036139.html protein_coding_gene CG6216 16-Dec-15 2015_12 viable FBgn0011617 l(1)I33g20 lethal (1) I33g20 http://flybase.net/reports/FBgn0011617.html FBgn0010206 gene l(1)33g20 16-Dec-15 2015_12 lethal FBgn0086062 snoRNA:Me28S-C788b http://flybase.net/reports/FBgn0086062.html snoRNA_gene "CR34691, DmSnR58b, Me28S-Cm788b" CR34691 16-Dec-15 2015_12 FBgn0005240 l(3)R78 lethal of Roberts 78 http://flybase.net/reports/FBgn0005240.html gene l(3)B78 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0045047 fs(1)261EL female sterile (1) 261EL http://flybase.net/reports/FBgn0045047.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile ovary FBgn0028104 l(3)S071710 lethal (3) S071710 http://flybase.net/reports/FBgn0028104.html gene 0717/10 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0032017 CG7810 http://flybase.net/reports/FBgn0032017.html protein_coding_gene 0005686=U2 snRNP "IPR018613=Protein of unknown function DUF2052, coiled-coil" CG7810 16-Dec-15 2015_12 WBGene00011194(R10D12.13) ENSXETG00000018736(CCDC97) ENSMUSG00000002608(Ccdc97) ENSG00000142039(CCDC97) viable FBgn0037760 FBXO11 F-box protein 11 http://flybase.net/reports/FBgn0037760.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination, 0070923=siRNA loading onto RISC involved in chromatin silencing by small RNA, 0060966=regulation of gene silencing by RNA" "0005737=cytoplasm, 0019005=SCF ubiquitin ligase complex, 0048471=perinuclear region of cytoplasm, 0000151=ubiquitin ligase complex" "FBX011, FBX011 ortholog, dFBX011, CG9461" "IPR011050=Pectin lyase fold/virulence factor, IPR001810=F-box domain, IPR006626=Parallel beta-helix repeat, IPR029799=F-box only protein 11, IPR006633=Carbohydrate-binding/sugar hydrolysis domain, IPR007742=Periplasmic copper-binding protein NosD, beta helix domain, IPR003126=Zinc finger, UBR-type, IPR022441=Parallel beta-helix repeat-2, IPR012334=Pectin lyase fold" CG9461 16-Dec-15 2015_12 "ENSDARG00000059973(fbxo11),ENSDARG00000061631" WBGene00001089(dre-1) ENSXETG00000022644() ENSMUSG00000005371(Fbxo11) ENSG00000138081(FBXO11) "viable,fertile" FBgn0011262 EnNuc-m Endonuclease mitochondrial http://flybase.net/reports/FBgn0011262.html gene 0004520=endodeoxyribonuclease activity "0000737=DNA catabolic process, endonucleolytic" 0005739=mitochondrion mitochondrial endonuclease 16-Dec-15 2015_12 FBgn0031317 CG5118 http://flybase.net/reports/FBgn0031317.html FBgn0044774 protein_coding_gene anon-WO0140519.11 "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG5118 16-Dec-15 2015_12 viable FBgn0044409 Scim18 Sensitized chromosome inheritance modifier 18 http://flybase.net/reports/FBgn0044409.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0022749 anon-E1 anon-E1 http://flybase.net/reports/FBgn0022749.html gene E1 16-Dec-15 2015_12 FBgn0040299 Myo28B1 Myosin 28B1 http://flybase.net/reports/FBgn0040299.html FBgn0031928 protein_coding_gene "0005524=ATP binding, 0000146=microfilament motor activity, 0003779=actin binding, 0003774=motor activity, 0030898=actin-dependent ATPase activity, 0042623=ATPase activity, coupled" 0030048=actin filament-based movement 0016459=myosin complex "CG6976, myosin VII 28B1-B4, VIIb 28B, myo 28B1, Myo28B, Myosin VII, Myosin VIIB, myo28B, DmVIIB, myosin VII (28B), Myo28B1, 28B" "IPR019749=Band 4.1 domain, IPR019748=FERM central domain, IPR000857=MyTH4 domain, IPR000048=IQ motif, EF-hand binding site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001609=Myosin head, motor domain, IPR029071=Ubiquitin-related domain, IPR018979=FERM, N-terminal, IPR000299=FERM domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6976 16-Dec-15 2015_12 ENSXETG00000007165() "viable,visible" "trichogen cell,male genitalia" FBgn0004542 l(4)102CDm lethal (4) 102CDm http://flybase.net/reports/FBgn0004542.html gene "l(4)CDm, l(4)27" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037519 CG3014 http://flybase.net/reports/FBgn0037519.html protein_coding_gene "IPR014756=Immunoglobulin E-set, IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain" CG3014 16-Dec-15 2015_12 ENSG00000197070(ARRDC1) FBgn0060651 l(3)S083407b lethal (3) S083407b http://flybase.net/reports/FBgn0060651.html gene "l(3)S083407, 0834/07" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053394 5SrRNA:CR33394 5SrRNA:CR33394 http://flybase.net/reports/FBgn0053394.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33394 CR33394 16-Dec-15 2015_12 FBgn0002853 Msp Muscle-specific protein http://flybase.net/reports/FBgn0002853.html gene 16-Dec-15 2015_12 ventral oblique muscle FBgn0041241 Gr47b Gustatory receptor 47b http://flybase.net/reports/FBgn0041241.html FBgn0050030 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "GR47F.1, 47F.1, Gr47F1, GR47b, CG30030, Gustatory receptor 47F.1" CG30030 16-Dec-15 2015_12 viable FBgn0069422 JJF064 JJF064 http://flybase.net/reports/FBgn0069422.html gene 16-Dec-15 2015_12 stress response defective FBgn0266803 CR45265 http://flybase.net/reports/FBgn0266803.html non_protein_coding_gene CR45265 16-Dec-15 2015_12 FBgn0259944 Ttd9 TRPL translocation defect 9 http://flybase.net/reports/FBgn0259944.html protein_coding_gene TRPL translocation defect 9 16-Dec-15 2015_12 FBgn0051717 CG31717 http://flybase.net/reports/FBgn0051717.html FBgn0061440 protein_coding_gene 0003824=catalytic activity 0016020=membrane "BcDNA:AT30094, Css2" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG31717 16-Dec-15 2015_12 "ENSDARG00000043513,ENSDARG00000043527(si:ch211-246k22.2),ENSDARG00000052033(LOC568758)" WBGene00020486(T13C5.6) "ENSXETG00000017360(PPAPDC2),ENSXETG00000001479(PPAPDC3)" "ENSMUSG00000040105(Ppapdc2),ENSMUSG00000051373(Ppapdc3)" "ENSG00000205808(PPAPDC2),ENSG00000160539(PPAPDC3)" "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0260295 GSd417 http://flybase.net/reports/FBgn0260295.html gene 16-Dec-15 2015_12 lethal FBgn0004998 cr-c cream c http://flybase.net/reports/FBgn0004998.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0025488 l(3)82EFc lethal (3) 82EFc http://flybase.net/reports/FBgn0025488.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0001266 Indented Indented http://flybase.net/reports/FBgn0001266.html gene Ind 16-Dec-15 2015_12 "visible,heat sensitive" "eye,heat sensitive" FBgn0036862 Gbs-76A Glycogen binding subunit 76A http://flybase.net/reports/FBgn0036862.html protein_coding_gene "0008599=protein phosphatase type 1 regulator activity, 0008157=protein phosphatase 1 binding" "GBS-76A, 149039_at, CG9619" IPR005036=CBM21 (carbohydrate binding type-21) domain CG9619 16-Dec-15 2015_12 "viable,fertile" FBgn0034529 FAM21 http://flybase.net/reports/FBgn0034529.html protein_coding_gene CG16742 CG16742 16-Dec-15 2015_12 ENSXETG00000007484() ENSMUSG00000024104(D6Wsu116e) "ENSG00000172661(FAM21C),ENSG00000099290(FAM21A),ENSG00000152726(FAM21B)" viable FBgn0001939 l(2)25Fe lethal (2) 25Fe http://flybase.net/reports/FBgn0001939.html gene l(2)gdh-3 16-Dec-15 2015_12 "lethal,recessive" FBgn0030955 CG6891 http://flybase.net/reports/FBgn0030955.html protein_coding_gene 0003779=actin binding 0019370=leukotriene biosynthetic process 0005622=intracellular "IPR030502=Coactosin-like protein, IPR002108=Actin-depolymerising factor homology domain, IPR029006=ADF-H/Gelsolin-like domain" CG6891 16-Dec-15 2015_12 ENSDARG00000026829 ENSXETG00000013325(cotl1) ENSMUSG00000031827(Cotl1) ENSG00000103187(COTL1) viable FBgn0003868 tt tilt http://flybase.net/reports/FBgn0003868.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective" "wing,wing vein L3,pigment cell" FBgn0013227 E(var)125 E(var)125 http://flybase.net/reports/FBgn0013227.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0031111 Obp19c Odorant-binding protein 19c http://flybase.net/reports/FBgn0031111.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "19c, Odorant binding protein 19c, DmelObp19c, CG15457" IPR006170=Pheromone/general odorant binding protein CG15457 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0058288 CG40288 http://flybase.net/reports/FBgn0058288.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083029 snoRNA:ë¬18S-525j snoRNA:ë¬18S-525j http://flybase.net/reports/FBgn0083029.html snoRNA_gene "psi18S-525j, CR34586" CR34586 16-Dec-15 2015_12 FBgn0005201 l(3)AM1 lethal (3) AM1 http://flybase.net/reports/FBgn0005201.html gene 16-Dec-15 2015_12 "lethal,dominant,partially" FBgn0082628 S(CycEJP)20S1 S(CycEJP)20S1 http://flybase.net/reports/FBgn0082628.html gene 20S1 16-Dec-15 2015_12 "lethal,recessive" FBgn0026566 CG1307 http://flybase.net/reports/FBgn0026566.html protein_coding_gene 0004045=aminoacyl-tRNA hydrolase activity 0005739=mitochondrion "hypothetical 23.1kd-like protein, BG:DS00004.12" "IPR023476=Peptidyl-tRNA hydrolase II domain, IPR002833=Peptidyl-tRNA hydrolase, PTH2" CG1307 16-Dec-15 2015_12 ENSDARG00000043487(ptrh2) YBL057C(PTH2) ENSXETG00000010737(PTRH2) ENSMUSG00000072582(Ptrh2) ENSG00000141378(PTRH2) FBgn0026570 CG5704 http://flybase.net/reports/FBgn0026570.html FBgn0035310 protein_coding_gene "BEST:LD30049, LD30049" "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG5704 16-Dec-15 2015_12 "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" "ENSG00000183569(SERHL2),ENSG00000172250" viable FBgn0051515 CG31515 http://flybase.net/reports/FBgn0051515.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG31515 16-Dec-15 2015_12 ENSDARG00000069736 DRSC13610 IE 3.641029502 3.459508277 4.668911547 4.633936408 -0.668408913 1.097790976 FBgn0060844 l(3)S049205 lethal (3) S049205 http://flybase.net/reports/FBgn0060844.html gene 0492/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0024547 l(3)L3659 lethal (3) L3659 http://flybase.net/reports/FBgn0024547.html gene 1(3)L3659 16-Dec-15 2015_12 "lethal,recessive" FBgn0004151 l(2)57Ae lethal (2) 57Ae http://flybase.net/reports/FBgn0004151.html gene 16-Dec-15 2015_12 lethal FBgn0052510 CG32510 http://flybase.net/reports/FBgn0052510.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262070 EG149 http://flybase.net/reports/FBgn0262070.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000631 fai faint http://flybase.net/reports/FBgn0000631.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval cuticle,cephalopharyngeal skeleton" FBgn0034782 CG12490 http://flybase.net/reports/FBgn0034782.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG12490 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "partially lethal - majority die,some die during pupal stage" FBgn0283455 EC2-12 Enhancer of CCT 2-12 http://flybase.net/reports/FBgn0283455.html gene 16-Dec-15 2015_12 FBgn0039443 TwdlS TweedleS http://flybase.net/reports/FBgn0039443.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix CG14242 IPR004145=Domain of unknown function DUF243 CG14242 16-Dec-15 2015_12 viable FBgn0267235 CR45675 http://flybase.net/reports/FBgn0267235.html non_protein_coding_gene lincRNA.426 CR45675 16-Dec-15 2015_12 FBgn0265344 CR44298 http://flybase.net/reports/FBgn0265344.html non_protein_coding_gene CR44298 16-Dec-15 2015_12 FBgn0060942 l(3)S039605c lethal (3) S039605c http://flybase.net/reports/FBgn0060942.html gene 0396/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0065795 l(2)SH0417 lethal (2) SH0417 http://flybase.net/reports/FBgn0065795.html gene l(2)SH2 0417 16-Dec-15 2015_12 "lethal,recessive" FBgn0022728 l(3)GPMG-30 lethal (3) GPMG-30 http://flybase.net/reports/FBgn0022728.html gene GPMG-30 16-Dec-15 2015_12 "lethal,recessive" FBgn0259250 EP-489 http://flybase.net/reports/FBgn0259250.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0028891 CG18482 http://flybase.net/reports/FBgn0028891.html FBgn0032564 protein_coding_gene "BG:DS03023.4, DS03023.4" 16-Dec-15 2015_12 viable DRSC01931 IK 0.054826439 -2.234369904 0.732995415 -0.420752721 -0.366047108 2.132660175 FBgn0044512 l(3)S007708 lethal (3) S007708 http://flybase.net/reports/FBgn0044512.html gene 0077/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0001651 l(1)ds3 lethal (1) discs small 3 http://flybase.net/reports/FBgn0001651.html gene l(1)d.sml.-3 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0261616 CG42705 http://flybase.net/reports/FBgn0261616.html protein_coding_gene CG47205 CG42705 16-Dec-15 2015_12 FBgn0036018 CG3335 http://flybase.net/reports/FBgn0036018.html protein_coding_gene "0003729=mRNA binding, 0003676=nucleic acid binding, 0000166=nucleotide binding, 0004386=helicase activity" "Q9VT19, Dm-RBD-1, cg3335" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG3335 16-Dec-15 2015_12 ENSDARG00000042590(rbm19) YPR112C(MRD1) WBGene00004315(rbd-1) ENSXETG00000017668(rbm19) ENSMUSG00000029594(Rbm19) ENSG00000122965(RBM19) FBgn0263777 CG43694 http://flybase.net/reports/FBgn0263777.html protein_coding_gene CG43694 16-Dec-15 2015_12 FBgn0067886 Mod(Prat:bw)1-1 Mod(Prat:bw)1-1 http://flybase.net/reports/FBgn0067886.html gene Mod-1-1 16-Dec-15 2015_12 FBgn0052289 tRNA:CR32289 transfer RNA:CR32289 http://flybase.net/reports/FBgn0052289.html FBgn0060269 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:C:GCA:AE002584-d, AE002584.trna15-CysGCA, CR32289, chr3L.trna15-CysGCA" CR32289 16-Dec-15 2015_12 FBgn0003570 Su(par) Suppressor of paralog http://flybase.net/reports/FBgn0003570.html gene 16-Dec-15 2015_12 FBgn0034050 CG8297 http://flybase.net/reports/FBgn0034050.html protein_coding_gene IPR012336=Thioredoxin-like fold CG8297 16-Dec-15 2015_12 ENSXETG00000010403(TXNDC15) ENSMUSG00000021497(Txndc15) viable FBgn0028130 l(3)S051311 lethal (3) S051311 http://flybase.net/reports/FBgn0028130.html gene 0513/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0050192 CG30192 http://flybase.net/reports/FBgn0050192.html FBgn0061432 protein_coding_gene BcDNA:AT30929 CG30192 16-Dec-15 2015_12 viable FBgn0267124 CR45564 http://flybase.net/reports/FBgn0267124.html non_protein_coding_gene lincRNA.916 CR45564 16-Dec-15 2015_12 FBgn0022273 l(2)k00213 lethal (2) k00213 http://flybase.net/reports/FBgn0022273.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039373 CG5024 http://flybase.net/reports/FBgn0039373.html "FBgn0061451, FBgn0065008" protein_coding_gene 0005509=calcium ion binding "gene1, BcDNA:AT16150" "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG5024 16-Dec-15 2015_12 viable FBgn0085230 CG34201 http://flybase.net/reports/FBgn0085230.html protein_coding_gene CG34201 16-Dec-15 2015_12 FBgn0038957 CG7059 http://flybase.net/reports/FBgn0038957.html protein_coding_gene 0004619=phosphoglycerate mutase activity 0006096=glycolytic process "IPR001345=Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR029033=Histidine phosphatase superfamily, IPR005952=Phosphoglycerate mutase 1, IPR013078=Histidine phosphatase superfamily, clade-1" CG7059 16-Dec-15 2015_12 "viable,fertile" DRSC16187 E -0.335509939 0.096334528 -1.626037336 -0.695894881 1.072807439 -0.133014348 FBgn0052468 CG32468 http://flybase.net/reports/FBgn0052468.html protein_coding_gene 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0029866 CG3842 http://flybase.net/reports/FBgn0029866.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process lincRNA.959 "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG3842 16-Dec-15 2015_12 YOR246C() WBGene00000985(dhs-22) "viable,fertile" FBgn0040634 CG4186 http://flybase.net/reports/FBgn0040634.html protein_coding_gene IPR009069=Cysteine alpha-hairpin motif superfamily CG4186 16-Dec-15 2015_12 ENSDARG00000068156(chchd7) ENSXETG00000026434(chchd7) ENSMUSG00000042198(Chchd7) ENSG00000170791(CHCHD7) viable FBgn0259460 C919 http://flybase.net/reports/FBgn0259460.html gene 16-Dec-15 2015_12 visible wing FBgn0002149 l(2)KE33 lethal (2) KE33 http://flybase.net/reports/FBgn0002149.html gene 16-Dec-15 2015_12 lethal FBgn0260450 CalpC Calpain C http://flybase.net/reports/FBgn0260450.html FBgn0030741 protein_coding_gene "0005509=calcium ion binding, 0004198=calcium-dependent cysteine-type endopeptidase activity" 0006508=proteolysis "0005737=cytoplasm, 0005622=intracellular" CG3692 "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR022683=Peptidase C2, calpain, domain III, IPR022684=Peptidase C2, calpain family, IPR022682=Peptidase C2, calpain, large subunit, domain III, IPR001300=Peptidase C2, calpain, catalytic domain" CG3692 16-Dec-15 2015_12 " larval stage , oogenesis stage && embryonic stage--adult stage " " larval salivary gland

, organism

" viable FBgn0051560 CG31560 http://flybase.net/reports/FBgn0051560.html FBgn0037425 protein_coding_gene CG10314 CG31560 16-Dec-15 2015_12 viable FBgn0031064 CG12531 http://flybase.net/reports/FBgn0031064.html protein_coding_gene "0015174=basic amino acid transmembrane transporter activity, 0015171=amino acid transmembrane transporter activity" 0003333=amino acid transmembrane transport 0016020=membrane "IPR002293=Amino acid/polyamine transporter I, IPR029485=Cationic amino acid transporter, C-terminal" CG12531 16-Dec-15 2015_12 ENSDARG00000010816(LOC100332474) "YEL063C(CAN1),YFL055W(AGP3),YBR069C(TAT1),YNL270C(ALP1),YNL268W(LYP1),YDR508C(GNP1),YCL025C(AGP1),YDR046C(BAP3),YBR068C(BAP2),YKR039W(GAP1),YOL020W(TAT2),YGR191W(HIP1),YPL274W(SAM3),YPL265W(DIP5),YLL061W(MMP1),YOR348C(PUT4),YBR132C(AGP2),YDR160W(SSY1)" ENSXETG00000009157(SLC7A14) ENSMUSG00000069072(Slc7a14) ENSG00000013293(SLC7A14) viable FBgn0003540 sts streaked sterni http://flybase.net/reports/FBgn0003540.html gene 16-Dec-15 2015_12 "visible,recessive,viable,poor,fertile,reduced,body color defective" sternite FBgn0034539 CG11159 http://flybase.net/reports/FBgn0034539.html protein_coding_gene 0003796=lysozyme activity "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0019730=antimicrobial humoral response" "IPR023346=Lysozyme-like domain, IPR019799=Glycoside hydrolase, family 22, conserved site, IPR001916=Glycoside hydrolase, family 22" CG11159 16-Dec-15 2015_12 ENSDARG00000057789(lyz) "ENSG00000151033(LYZL2),ENSG00000120563(LYZL1),ENSG00000141316(SPACA3),ENSG00000171478(SPACA5B),ENSG00000171489(SPACA5),ENSG00000161572(LYZL6),ENSG00000157093(LYZL4)" FBgn0067669 p105 p105 http://flybase.net/reports/FBgn0067669.html gene 16-Dec-15 2015_12 FBgn0051907 CG31907 http://flybase.net/reports/FBgn0051907.html "FBgn0045995, FBgn0046003, FBgn0046085" protein_coding_gene 0008017=microtubule binding 0015630=microtubule cytoskeleton "NEST:bs29b10, NEST:bs06f02, NEST:bs25f07" "IPR027328=Microtubule-associated protein RP/EB, IPR001715=Calponin homology domain" CG31907 16-Dec-15 2015_12 viable DRSC00967 IE 1.503585057 0.354032456 1.613227878 0.611293931 0.228689891 -0.44140417 FBgn0023132 Z66 Z66 http://flybase.net/reports/FBgn0023132.html gene 16-Dec-15 2015_12 FBgn0052230 ND-MLRQ NADH dehydrogenase (ubiquinone) MLRQ subunit http://flybase.net/reports/FBgn0052230.html "FBan0032230, FBgn0043838, FBgn0047088" protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH-ubiquinone oxidoreductase MLRQ subunit, NADH ubiquinone oxidoreductase MLRQ, NADH:ubiquinone oxidoreductase MLRQ subunit, BcDNA:RE56733, CG32230, BEST:GH04411, NUML" IPR010530=NADH-ubiquinone reductase complex 1 MLRQ subunit CG32230 16-Dec-15 2015_12 "ENSDARG00000038212(ndufa4l),ENSDARG00000070690(LOC100330344),ENSDARG00000056108(ndufa4)" "ENSXETG00000008232(),ENSXETG00000017833()" "ENSMUSG00000029632(Ndufa4),ENSMUSG00000040280(Ndufa4l2)" "ENSG00000189043(NDUFA4),ENSG00000185633(NDUFA4L2)" "viable,fertile" DRSC11913 E -1.014917992 -0.660773253 -2.029159282 -0.854329629 1.364449046 0.13089929 FBgn0083267 E(smoDN)418 Enhancer of smoDN 418 http://flybase.net/reports/FBgn0083267.html gene 16-Dec-15 2015_12 FBgn0023003 l(4)K-2 lethal (4) K-2 http://flybase.net/reports/FBgn0023003.html gene 16-Dec-15 2015_12 lethal FBgn0025482 l(3)Ax7 lethal (3) Ax7 http://flybase.net/reports/FBgn0025482.html gene Ax7 16-Dec-15 2015_12 "lethal,recessive" FBgn0004155 l(2)51Db lethal (2) 51Db http://flybase.net/reports/FBgn0004155.html gene 16-Dec-15 2015_12 "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005098 fs(3)108-17 female sterile (3) 108-17 http://flybase.net/reports/FBgn0005098.html gene 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,endochorion" FBgn0085159 l(3)S009515 l(3)S009515 http://flybase.net/reports/FBgn0085159.html gene 16-Dec-15 2015_12 FBgn0083971 CG34135 http://flybase.net/reports/FBgn0083971.html protein_coding_gene CG34135 16-Dec-15 2015_12 FBgn0005243 l(3)R112 lethal of Roberts 112 http://flybase.net/reports/FBgn0005243.html gene l(3)112 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0024672 l(2)k02113 lethal (2) k02113 http://flybase.net/reports/FBgn0024672.html gene 21/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0083094 cia ciambella http://flybase.net/reports/FBgn0083094.html gene "0007110=meiosis I cytokinesis, 0007111=meiosis II cytokinesis, 0000916=actomyosin contractile ring contraction, 0043147=meiotic spindle stabilization" 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male" FBgn0270925 CG4836 http://flybase.net/reports/FBgn0270925.html "FBgn0038762, FBgn0044598, FBgn0044779, FBgn0003504" protein_coding_gene "0003939=L-iditol 2-dehydrogenase activity, 0008270=zinc ion binding" 0055114=oxidation-reduction process "SODH-1, bs15h04.y1, anon-WO0140519.33, Srd, L-iditol 2-dehydrogenase, bs36e10.y1, anon-WO0140519.105, Sorbitol dehydrogenase, DM_7300579" "IPR013154=Alcohol dehydrogenase, N-terminal, IPR011032=GroES-like, IPR002085=Alcohol dehydrogenase superfamily, zinc-type" CG4836 16-Dec-15 2015_12 "partially lethal - majority die,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0004501 fs(1)ë_a6 female sterile (1) ë_a6 http://flybase.net/reports/FBgn0004501.html gene 16-Dec-15 2015_12 FBgn0028365 l(1)G0011 lethal (1) G0011 http://flybase.net/reports/FBgn0028365.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0053144 CG33144 http://flybase.net/reports/FBgn0053144.html "FBgn0033545, FBgn0033546" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process "lincRNA.281, CG7621, AAF58756.2, CG12339" "IPR001841=Zinc finger, RING-type, IPR002867=IBR domain, IPR031127=E3 ubiquitin ligase RBR family, IPR017907=Zinc finger, RING-type, conserved site" CG33144 16-Dec-15 2015_12 "ENSDARG00000020284(si:ch211-278j3.3),ENSDARG00000012040(LOC557995)" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC07024 E 0.007413568 -0.576921436 3.38040597 0.770979179 -0.008975287 -0.21984095 FBgn0033574 Spn47C Serpin 47C http://flybase.net/reports/FBgn0033574.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "spn47C, CG7722" "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG7722 16-Dec-15 2015_12 "ENSMUSG00000045827(Serpinb9),ENSMUSG00000021403(Serpinb9b),ENSMUSG00000062342(Serpinb9e),ENSMUSG00000038327(Serpinb9f),ENSMUSG00000054266(Serpinb9d),ENSMUSG00000071452(Gm11397),ENSMUSG00000057726(Serpinb9g),ENSMUSG00000021404(Serpinb9c),ENSMUSG00000060147(Serpinb6a),ENSMUSG00000026315(Serpinb8),ENSMUSG00000042842(Serpinb6b),ENSMUSG00000052180(Serpinb6c),ENSMUSG00000047889(Serpinb6d),ENSMUSG00000069248(Serpinb6e)" viable FBgn0040933 CG15315 http://flybase.net/reports/FBgn0040933.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036421 CG13481 http://flybase.net/reports/FBgn0036421.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination 0005634=nucleus "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG13481 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0267498 18SrRNA:CR45838 18S ribosomal RNA:CR45838 http://flybase.net/reports/FBgn0267498.html rRNA_gene CR45838 CR45838 16-Dec-15 2015_12 FBgn0031730 CG7236 http://flybase.net/reports/FBgn0031730.html FBgn0043013 protein_coding_gene "0005524=ATP binding, 0004693=cyclin-dependent protein serine/threonine kinase activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0000281=mitotic cytokinesis, 0006468=protein phosphorylation" "0005634=nucleus, 0005737=cytoplasm" "KKIALRE, AC018104, CG7236/Cdk1l" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG7236 16-Dec-15 2015_12 ENSDARG00000017329(cdkl1) WBGene00012779(Y42A5A.4) ENSXETG00000019709(CDKL1) "ENSMUSG00000020990(Cdkl1),ENSMUSG00000033966(Cdkl4)" ENSG00000205111(CDKL4) FBgn0027113 mei-P44 mei-P44 http://flybase.net/reports/FBgn0027113.html gene 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0053440 5SrRNA:CR33440 5SrRNA:CR33440 http://flybase.net/reports/FBgn0053440.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33440 CR33440 16-Dec-15 2015_12 FBgn0000376 crm cramped http://flybase.net/reports/FBgn0000376.html protein_coding_gene 0003682=chromatin binding "0007379=segment specification, 0006355=regulation of transcription, DNA-templated, 0006260=DNA replication" 0005634=nucleus "l(1)zw9, EG:95B7.2, zw9, l(1)3C1, swa, sta[P], stubarista from P32, ZW-9, zw-9, CG2714, swollen-antenna, sparse-arista, sa, l(1)3Ca" IPR001005=SANT/Myb domain CG2714 16-Dec-15 2015_12 ENSXETG00000020224(CRAMP1L) ENSMUSG00000038002(Cramp1l) ENSG00000007545(CRAMP1L) " embryonic stage , larval stage | third instar , embryonic stage | early " " pole cell

, embryonic nervous system

, embryonic/larval salivary gland

, gonad

" "viable,fertile,wild-type,lethal,recessive,male sterile,visible,female sterile,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,male,reduced,male fertile,female,poor,female fertile,partially,maternal effect,polyphasic,eye color defective,body color defective,sterile,suppressor of variegation,dominant,temperature conditional,size defective" "sex comb & prothoracic tarsal segment 2,sex comb & mesothoracic tarsal segment 2,postvertical bristle,wing,arista,antenna,third segment of antenna,sex comb,ectopic,ovary,prothoracic leg,mesothoracic leg,metathoracic leg,eye,tarsal segment 2,ovariole,germline clone,leg,prothoracic tarsal segment 2,pigment cell,supernumerary,temperature conditional,adult abdomen,wing margin,wing disc,adult thorax" FBgn0264286 Su(Mir)1F2-3 http://flybase.net/reports/FBgn0264286.html gene 16-Dec-15 2015_12 FBgn0028694 Rpn11 Regulatory particle non-ATPase 11 http://flybase.net/reports/FBgn0028694.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" "0005838=proteasome regulatory particle, 0005875=microtubule associated complex, 0000502=proteasome complex, 0008541=proteasome regulatory particle, lid subcomplex" "Q9V3H2, rpn11, yippee interacting protein 5, Rpn11, DmS13, RPN11, 37B, yip5, CG18174, S13, p37B, RPn11" "IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR024969=Rpn11/EIF3F, C-terminal" CG18174 16-Dec-15 2015_12 ENSDARG00000063100(psmd14) YFR004W(RPN11) WBGene00004467(rpn-11) ENSXETG00000016202(psmd14) ENSMUSG00000026914(Psmd14) ENSG00000115233(PSMD14) "lethal - all die before end of larval stage,some die during larval stage,lethal,short lived,visible,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,progressive,eye,wing,wing margin bristle" DRSC03422 IEK -3.097075604 -2.940798446 -4.987137804 -3.422478875 -0.45211326 -1.711354921 FBgn0013242 E(var)231 E(var)231 http://flybase.net/reports/FBgn0013242.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0061064 l(3)S021204b lethal (3) S021204b http://flybase.net/reports/FBgn0061064.html gene 0212/04 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0021925 l(2)k11206 lethal (2) k11206 http://flybase.net/reports/FBgn0021925.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0054031 CG34031 http://flybase.net/reports/FBgn0054031.html "FBan0034031, FBgn0082838" protein_coding_gene 0043565=sequence-specific DNA binding "0006355=regulation of transcription, DNA-templated" "BP1068, unnamed, CR34031, CG34031" "IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG34031 16-Dec-15 2015_12 "ENSDARG00000070954(hmx2),ENSDARG00000007941(hmx4)" "ENSMUSG00000055942(Gm4745),ENSMUSG00000074366(Obox5),ENSMUSG00000074369(Gm5889),ENSMUSG00000066772(Obox3),ENSMUSG00000054310(Obox1),ENSMUSG00000074372,ENSMUSG00000074368,ENSMUSG00000044538,ENSMUSG00000041583(Obox6),ENSMUSG00000040953,ENSMUSG00000079206,ENSMUSG00000079203,ENSMUSG00000079205,ENSMUSG00000074370(Gm10678),ENSMUSG00000074371(Gm10679),ENSMUSG00000079204" FBgn0085687 CG41556 http://flybase.net/reports/FBgn0085687.html FBan0041556 protein_coding_gene 16-Dec-15 2015_12 FBgn0027607 CG8230 http://flybase.net/reports/FBgn0027607.html protein_coding_gene BcDNA:GH02536 IPR019142=Dymeclin CG8230 16-Dec-15 2015_12 ENSDARG00000042555(LOC572325) WBGene00008136(C47D12.2) ENSXETG00000020310(dym) ENSMUSG00000035765(Dym) ENSG00000141627(DYM) viable FBgn0036290 CG10638 http://flybase.net/reports/FBgn0036290.html "FBgn0046345, FBgn0052101" protein_coding_gene 0004032=alditol:NADP+ 1-oxidoreductase activity "0055114=oxidation-reduction process, 0006081=cellular aldehyde metabolic process" "CG32101, anon-WO0172774.89, aldo-keto reductase, AKR" "IPR001395=Aldo/keto reductase, IPR018170=Aldo/keto reductase, conserved site, IPR023210=NADP-dependent oxidoreductase domain, IPR020471=Aldo/keto reductase subgroup" CG10638 16-Dec-15 2015_12 "YOR120W(GCY1),YDR368W(YPR1)" "viable,fertile" DRSC09762 E 1.455188505 0.610534036 3.778715186 0.730468809 0.005748208 0.969895056 FBgn0051526 CG31526 http://flybase.net/reports/FBgn0051526.html FBan0031526 protein_coding_gene CG31526 16-Dec-15 2015_12 viable FBgn0263260 sel seele http://flybase.net/reports/FBgn0263260.html "FBgn0069083, FBgn0033477" protein_coding_gene "0009951=polarity specification of dorsal/ventral axis, 0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0050708=regulation of protein secretion, 0070613=regulation of protein processing" "0005783=endoplasmic reticulum, 0012505=endomembrane system" "Sle, CG12918, Seele" IPR021852=Domain of unknown function DUF3456 CG12918 16-Dec-15 2015_12 "ENSDARG00000007207(cnpy2),ENSDARG00000003757(cnpy1)" WBGene00017169(F01F1.15) "ENSXETG00000013497(CNPY1),ENSXETG00000009510(tmem4)" ENSMUSG00000025381(Cnpy2) ENSG00000144785 FBgn0037151 CG7130 http://flybase.net/reports/FBgn0037151.html protein_coding_gene 0009408=response to heat "IPR018253=DnaJ domain, conserved site, IPR001623=DnaJ domain" CG7130 16-Dec-15 2015_12 viable FBgn0015379 dod dodo http://flybase.net/reports/FBgn0015379.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity 0007173=epidermal growth factor receptor signaling pathway 0005634=nucleus "CG17051, Pin1" "IPR023058=Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site, IPR001202=WW domain, IPR000297=Peptidyl-prolyl cis-trans isomerase, PpiC-type" CG17051 16-Dec-15 2015_12 YJR017C(ESS1) WBGene00022448(Y110A2AL.13) ENSXETG00000005855(Q642N3_XENTR) ENSMUSG00000032171(Pin1) ENSG00000127445(PIN1) viable FBgn0020771 wv wv http://flybase.net/reports/FBgn0020771.html gene 16-Dec-15 2015_12 visible wing FBgn0002089 l(2)55i lethal (2) 55i http://flybase.net/reports/FBgn0002089.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0267495 CR45185 http://flybase.net/reports/FBgn0267495.html "FBgn0266695, FBgn0266746" non_protein_coding_gene CR45219 CR45185 16-Dec-15 2015_12 FBgn0005247 l(3)R200 lethal of Roberts 200 http://flybase.net/reports/FBgn0005247.html gene l(3)200 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0086706 pix pixie http://flybase.net/reports/FBgn0086706.html "FBgn0035946, FBgn0045819, FBgn0064145" protein_coding_gene "0016887=ATPase activity, 0008428=ribonuclease inhibitor activity, 0043024=ribosomal small subunit binding, 0051536=iron-sulfur cluster binding, 0005524=ATP binding" "0016049=cell growth, 0043524=negative regulation of neuron apoptotic process, 0006412=translation, 0040007=growth, 0006413=translational initiation, 0070481=nuclear-transcribed mRNA catabolic process, non-stop decay, 0016071=mRNA metabolic process" "0005737=cytoplasm, 0005739=mitochondrion, 0005852=eukaryotic translation initiation factor 3 complex" "BEST:GH18088, CG5651, E3-c, ABCE1, Pixie, pixie" "IPR017871=ABC transporter, conserved site, IPR013283=ABC transporter ABCE, IPR007209=RNase L inhibitor RLI, possible metal-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR003439=ABC transporter-like, IPR017900=4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR003593=AAA+ ATPase domain" CG5651 16-Dec-15 2015_12 ENSDARG00000007216(abce1) YDR091C(RLI1) WBGene00012714(abce-1) ENSXETG00000025168(abce1) ENSMUSG00000058355(Abce1) ENSG00000164163(ABCE1) DRSC10533 EK -0.717102901 0.220478252 1.733002634 -1.354949744 -0.31188342 2.370738049 FBgn0002974 nw narrow http://flybase.net/reports/FBgn0002974.html gene "Blade, Bla, lance" 16-Dec-15 2015_12 "visible,dominant,lethal,recessive,female fertile,reduced,female sterile,male sterile,viable,poor,fertile" "wing,wing margin bristle,ovary,oogonial cell,egg chamber" FBgn0260482 CG32599 http://flybase.net/reports/FBgn0260482.html "FBgn0052599, FBgn0030557" protein_coding_gene "CG12047, GM07807" CG32599 16-Dec-15 2015_12 viable FBgn0031782 WDR79 WD repeat domain 79 homolog http://flybase.net/reports/FBgn0031782.html protein_coding_gene "0019001=guanyl nucleotide binding, 0034512=box C/D snoRNA binding" 0030576=Cajal body organization 0015030=Cajal body "p70, CG9226, dWDR79" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG9226 16-Dec-15 2015_12 ENSXETG00000014943(WRAP53) ENSMUSG00000041346(Wrap53) ENSG00000141499(WRAP53) "viable,fertile" "Cajal body,Cajal bodyda.PU" FBgn0060555 l(3)S097408 lethal (3) S097408 http://flybase.net/reports/FBgn0060555.html gene 0974/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002966 nr nesher http://flybase.net/reports/FBgn0002966.html gene 16-Dec-15 2015_12 FBgn0033773 Mos Mos oncogene http://flybase.net/reports/FBgn0033773.html protein_coding_gene "0005524=ATP binding, 0016301=kinase activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0048599=oocyte development, 0007050=cell cycle arrest, 0032008=positive regulation of TOR signaling, 0006468=protein phosphorylation, 0043410=positive regulation of MAPK cascade" 0005737=cytoplasm "D-mos, mos, MOS, dmos, CG8767, DMOS" "IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG8767 16-Dec-15 2015_12 ENSDARG00000069744(mos) ENSXETG00000005653(MOS) ENSMUSG00000078365(Mos) ENSG00000172680(MOS) "viable,male fertile,female semi-sterile,increased cell death" ovary DRSC07258 E -1.015046391 0.321482375 -1.737465678 0.759144058 -0.176972329 0.108918286 FBgn0266355 CR45003 http://flybase.net/reports/FBgn0266355.html non_protein_coding_gene CR45003 16-Dec-15 2015_12 FBgn0014140 chec che caos http://flybase.net/reports/FBgn0014140.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male,male sterile,female sterile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" spindle FBgn0036734 CG7564 http://flybase.net/reports/FBgn0036734.html protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome, 0006376=mRNA splice site selection" "0071011=precatalytic spliceosome, 0005685=U1 snRNP" Alsin2 IPR004882=Luc7-related CG7564 16-Dec-15 2015_12 "ENSDARG00000055903(luc7l),ENSDARG00000019765(zgc:158803)" YDL087C(LUC7) WBGene00015207(B0495.8) "ENSXETG00000000229(luc7l2),ENSXETG00000011562(luc7l)" "ENSMUSG00000024188(Luc7l),ENSMUSG00000029823(Luc7l2)" "ENSG00000007392(LUC7L),ENSG00000146963(LUC7L2)" "viable,visible" mesothoracic tergum DRSC10880 IK 2.576048087 -0.637347914 0.285858667 -0.447730023 1.560449189 1.597239532 FBgn0069412 JJF171 JJF171 http://flybase.net/reports/FBgn0069412.html gene 16-Dec-15 2015_12 stress response defective FBgn0262766 Mst77Y-18ë¬ Male-specific pseudogene 77Y 18 http://flybase.net/reports/FBgn0262766.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0027350 anon-93Bc anon-93Bc http://flybase.net/reports/FBgn0027350.html gene 16-Dec-15 2015_12 FBgn0005244 l(3)R138 lethal of Roberts 138 http://flybase.net/reports/FBgn0005244.html gene l(3)138 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0082907 Alh::Hsap\KMT2A MLL http://flybase.net/reports/FBgn0082907.html engineered_fusion_gene Alh::Hsap\MLL 16-Dec-15 2015_12 FBgn0259537 GG01510 http://flybase.net/reports/FBgn0259537.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,leg,arista,wing,third segment of antenna" FBgn0266654 CR45161 http://flybase.net/reports/FBgn0266654.html non_protein_coding_gene CR45161 16-Dec-15 2015_12 FBgn0005716 l(1)TK121 lethal (1) TK121 http://flybase.net/reports/FBgn0005716.html gene l121 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0267749 CR46080 http://flybase.net/reports/FBgn0267749.html non_protein_coding_gene CR46080 16-Dec-15 2015_12 FBgn0263343 CR43424 http://flybase.net/reports/FBgn0263343.html non_protein_coding_gene CR43424 16-Dec-15 2015_12 FBgn0082934 snoRNA:Me28S-G1083b snoRNA:Me28S-G1083b http://flybase.net/reports/FBgn0082934.html snoRNA_gene 0030562=rRNA 2'-O-ribose methylation guide activity 0000451=rRNA 2'-O-methylation 0005730=nucleolus "Me28S-Gm1083b, DmSnR60, CR34563, DmSnR60b" CR34563 16-Dec-15 2015_12 FBgn0266383 CR45025 http://flybase.net/reports/FBgn0266383.html non_protein_coding_gene CR45025 16-Dec-15 2015_12 FBgn0030354 Upf1 Upf1 http://flybase.net/reports/FBgn0030354.html protein_coding_gene "0004386=helicase activity, 0003677=DNA binding, 0005524=ATP binding, 0008270=zinc ion binding" "0071456=cellular response to hypoxia, 2000624=positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0035195=gene silencing by miRNA, 0016246=RNA interference" "0035145=exon-exon junction complex, 0005737=cytoplasm" "DmUpf1, CG1559, Upf1p, UPF1, upf1, smg-2, Dm-Upf1, up-frameshift suppressor 1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR018999=RNA helicase UPF1, UPF2-interacting domain" CG1559 16-Dec-15 2015_12 ENSDARG00000016302(upf1) YMR080C(NAM7) WBGene00004880(smg-2) ENSXETG00000013602(UPF1) ENSMUSG00000058301(Upf1) ENSG00000005007(UPF1) "lethal - all die before end of larval stage,lethal,mitotic cell cycle defective,germline clone,lethal - all die before end of second instar larval stage,male limited,some die during second instar larval stage,some die during third instar larval stage" "adult tracheal system,somatic clone,eye,dorsal appendage,germline clone,follicle cell" DRSC19667 I -0.535036313 -2.556182212 -0.817297391 -1.353204726 0.717216744 0.213075128 FBgn0032553 CG4480 http://flybase.net/reports/FBgn0032553.html protein_coding_gene CG4480 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0002396 l(3)93Fc lethal (3) 93Fc http://flybase.net/reports/FBgn0002396.html gene "er18, l(3)er18" 16-Dec-15 2015_12 "visible,recessive,female sterile,lethal,partially" wing FBgn0037383 CG2023 http://flybase.net/reports/FBgn0037383.html protein_coding_gene 0005484=SNAP receptor activity 0016320=endoplasmic reticulum membrane fusion "0005783=endoplasmic reticulum, 0031201=SNARE complex" "Sec20, Cg2023, lincRNA.683" IPR005606=Sec20 CG2023 16-Dec-15 2015_12 ENSXETG00000012728(BNIP1) ENSMUSG00000024191(Bnip1) ENSG00000113734(BNIP1) FBgn0036214 CG7264 http://flybase.net/reports/FBgn0036214.html protein_coding_gene IPR008805=RIB43A CG7264 16-Dec-15 2015_12 ENSDARG00000055739(ribc1) "ENSXETG00000022016(RIBC1),ENSXETG00000003068(RIBC2)" ENSMUSG00000022431(Ribc2) ENSG00000128408(RIBC2) viable FBgn0266706 CR45196 http://flybase.net/reports/FBgn0266706.html non_protein_coding_gene CR45196 16-Dec-15 2015_12 FBgn0250749 ë±-Spec::ë_-Spec http://flybase.net/reports/FBgn0250749.html engineered_fusion_gene 16-Dec-15 2015_12 lethal FBgn0001414 l(1)3Ed lethal (1) 3Ed http://flybase.net/reports/FBgn0001414.html gene "l(1)GA2, l(1)GA58, JC43" 16-Dec-15 2015_12 "lethal,recessive" FBgn0260351 GSd489 http://flybase.net/reports/FBgn0260351.html gene 16-Dec-15 2015_12 lethal FBgn0010588 l(2)05006 lethal (2) 05006 http://flybase.net/reports/FBgn0010588.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260056 2L3918 http://flybase.net/reports/FBgn0260056.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0002047 l(2)37Ea lethal (2) 37Ea http://flybase.net/reports/FBgn0002047.html gene l(2)E124 16-Dec-15 2015_12 "lethal,heat sensitive,recessive" FBgn0011740 ë±-Man-IIa ë±-Mannosidase class II a http://flybase.net/reports/FBgn0011740.html "FBgn0037691, FBgn0042203" protein_coding_gene "0008270=zinc ion binding, 0030246=carbohydrate binding, 0015923=mannosidase activity, 0004572=mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity" "0006013=mannose metabolic process, 0006491=N-glycan processing, 0035010=encapsulation of foreign target, 0006517=protein deglycosylation, 0006487=protein N-linked glycosylation, 0016063=rhodopsin biosynthetic process, 0006486=protein glycosylation" "0005783=endoplasmic reticulum, 0005795=Golgi stack, 0000139=Golgi membrane" "Golgi mannosidase II, alpha-Man-II, mannosidase II, Golgi alpha-mannosidase, MAN-2, Chain A, Golgi Alpha-Mannosidase Ii, dGMIIb, Golgi Man II, GMII, alpha-Mannosidase class II a, alpha Mannosidase II, alpha-mannosidase II, alpha-Man-IIa, DM-GII.1, alpha-mannosidase 2, dGMII, Man, Golgi alpha-mannosidase II, CG8139, alpha-mannosidase-II, Man-II, alpha mannosidase II, CG18474, CG18802, GmII" "IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR000602=Glycoside hydrolase family 38, N-terminal domain, IPR011013=Galactose mutarotase-like domain, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR015341=Glycoside hydrolase, family 38, central domain, IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel" CG18802 16-Dec-15 2015_12 "ENSDARG00000063101,ENSDARG00000059669" WBGene00010284(aman-2) ENSXETG00000015458(MAN2A2) "ENSMUSG00000024085(Man2a1),ENSMUSG00000038886(Man2a2)" "ENSG00000112893(MAN2A1),ENSG00000196547(MAN2A2)" "visible,long lived,viable,immune response defective" eye FBgn0005015 dipp-6 defective in phototaxis plasticity 6 http://flybase.net/reports/FBgn0005015.html gene 16-Dec-15 2015_12 "neurophysiology defective,mating defective,female,visual behavior defective,phototaxis defective" photoreceptor FBgn0065985 iab-4-2.s iab-4-2.s http://flybase.net/reports/FBgn0065985.html gene 4-2 s 16-Dec-15 2015_12 FBgn0061502 l(2)44Fn lethal (2) 44Fn http://flybase.net/reports/FBgn0061502.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005409 l(1)11Ai lethal (1) 11Ai http://flybase.net/reports/FBgn0005409.html gene 16-Dec-15 2015_12 lethal FBgn0065611 l(2)SH0837 lethal (2) SH0837 http://flybase.net/reports/FBgn0065611.html gene l(2)SH2 0837 16-Dec-15 2015_12 "lethal,recessive" FBgn0060672 l(3)S078708 lethal (3) S078708 http://flybase.net/reports/FBgn0060672.html gene 0787/08 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0083046 snoRNA:ë¬18S-1389a snoRNA:ë¬18S-1389a http://flybase.net/reports/FBgn0083046.html snoRNA_gene "chr2R:16841577..16841810, CR34556, Psi 18S-1389a, psi18s-1389a" CR34556 16-Dec-15 2015_12 FBgn0266892 CR45352 http://flybase.net/reports/FBgn0266892.html non_protein_coding_gene CR45352 16-Dec-15 2015_12 FBgn0002546 lfb little faint ball http://flybase.net/reports/FBgn0002546.html gene 0007391=dorsal closure 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" dorsal closure embryo FBgn0044100 E(rst)C544 E(rst)C544 http://flybase.net/reports/FBgn0044100.html gene 0001745=compound eye morphogenesis C544 16-Dec-15 2015_12 FBgn0050277 Oatp58Da Organic anion transporting polypeptide 58Da http://flybase.net/reports/FBgn0050277.html FBgn0034714 protein_coding_gene "0008514=organic anion transmembrane transporter activity, 0005215=transporter activity" "0015711=organic anion transport, 0006810=transport" 0016020=membrane "CG3387, CG30277, oatp 58Da" "IPR002350=Kazal domain, IPR004156=Organic anion transporter polypeptide OATP, IPR020846=Major facilitator superfamily domain" CG30277 16-Dec-15 2015_12 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040977 CG15292 http://flybase.net/reports/FBgn0040977.html protein_coding_gene 16-Dec-15 2015_12 FBgn0058230 CG40230 http://flybase.net/reports/FBgn0058230.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083012 snoRNA:ë¬28S-1135a snoRNA:ë¬28S-1135a http://flybase.net/reports/FBgn0083012.html snoRNA_gene "Psi 28S-1135a, Psi28S-1135a, psi28S-1135a, chrX:16980527..16980719, CR34606, Psi28S-1135" CR34606 16-Dec-15 2015_12 FBgn0063497 GstE3 Glutathione S transferase E3 http://flybase.net/reports/FBgn0063497.html "FBgn0034337, FBgn0043828" protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GSTE3, E3, BEST:GH09055, GST-E3, gste3, CG17524, DmGSTE3" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal" CG17524 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0038129 CG8449 http://flybase.net/reports/FBgn0038129.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity IPR000195=Rab-GTPase-TBC domain CG8449 16-Dec-15 2015_12 WBGene00007167(rbg-3) viable FBgn0032524 CG9267 http://flybase.net/reports/FBgn0032524.html protein_coding_gene Q9VJX8 "IPR007482=Protein-tyrosine phosphatase-like, PTPLA, IPR008978=HSP20-like chaperone, IPR007052=CS domain" CG9267 16-Dec-15 2015_12 ENSDARG00000016038(ptplad1) ENSMUSG00000033629(Ptplad1) ENSG00000074696(PTPLAD1) "viable,fertile" FBgn0013298 MT:DNA Mitochondrial DNA http://flybase.net/reports/FBgn0013298.html FBgn0003457 mitochondrial_sequence "mtDNA, MtDNA" 16-Dec-15 2015_12 FBgn0261919 Amph::EndoA http://flybase.net/reports/FBgn0261919.html engineered_fusion_gene Amph::endoA 16-Dec-15 2015_12 FBgn0013466 grunt grunt http://flybase.net/reports/FBgn0013466.html gene 0007625=grooming behavior 16-Dec-15 2015_12 "flightless,recessive,behavior defective" FBgn0029178 E(Khc)ek9 E(Khc)ek9 http://flybase.net/reports/FBgn0029178.html gene 16-Dec-15 2015_12 FBgn0002490 l(3)SG50 lethal (3) SG50 http://flybase.net/reports/FBgn0002490.html gene l(3)7m-75 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0033460 Sec24AB Sec24AB ortholog (H. sapiens) http://flybase.net/reports/FBgn0033460.html protein_coding_gene "0005048=signal sequence binding, 0008270=zinc ion binding, 0005215=transporter activity" "0006886=intracellular protein transport, 0006888=ER to Golgi vesicle-mediated transport, 0090110=cargo loading into COPII-coated vesicle" "0030134=ER to Golgi transport vesicle, 0030127=COPII vesicle coat" "Hau, Sec24AB, sec24, SEC24, CG1472, Sec24" "IPR002035=von Willebrand factor, type A, IPR006900=Sec23/Sec24, helical domain, IPR006895=Zinc finger, Sec23/Sec24-type, IPR006896=Sec23/Sec24, trunk domain, IPR012990=Sec23/Sec24 beta-sandwich, IPR007123=Gelsolin-like domain, IPR029006=ADF-H/Gelsolin-like domain" CG1472 16-Dec-15 2015_12 "ENSDARG00000071906,ENSDARG00000068597" "YIL109C(SEC24),YNL049C(SFB2)" WBGene00004756(sec-24.2) "ENSXETG00000021091(SEC24B),ENSXETG00000010407(SEC24A)" "ENSMUSG00000001052(Sec24b),ENSMUSG00000036391(Sec24a)" "ENSG00000138802(SEC24B),ENSG00000113615(SEC24A)" viable FBgn0025006 E(var)129-1 E(var)129-1 http://flybase.net/reports/FBgn0025006.html gene E-129/1 16-Dec-15 2015_12 FBgn0004157 l(2)Ta lethal (2) with Thickened arista http://flybase.net/reports/FBgn0004157.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" FBgn0003353 sei seizure http://flybase.net/reports/FBgn0003353.html protein_coding_gene "0022843=voltage-gated cation channel activity, 0005249=voltage-gated potassium channel activity" "0007605=sensory perception of sound, 0006813=potassium ion transport, 0055085=transmembrane transport" 0008076=voltage-gated potassium channel complex "eag related gene, erg, CG3182, Seizure/HERG, sei, seizure potassium channel, Ether-a-go-go-related, Derg" "IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain, IPR005821=Ion transport domain, IPR014710=RmlC-like jelly roll fold, IPR003938=Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR003967=Potassium channel, voltage-dependent, ERG" CG3182 16-Dec-15 2015_12 "ENSDARG00000062687,ENSDARG00000010296,ENSDARG00000060053" WBGene00006830(unc-103) "ENSXETG00000006509(KCNH2),ENSXETG00000005312(KCNH6),ENSXETG00000013171(KCNH7)" "ENSMUSG00000001901(Kcnh6),ENSMUSG00000038319(Kcnh2),ENSMUSG00000059742(Kcnh7)" " adult stage , embryonic stage " embryonic central nervous system

"neuroanatomy defective,heat sensitive,visible,wild-type,paralytic,behavior defective,temperature conditional,neurophysiology defective,codominant,viable,locomotor behavior defective,auditory perception defective,lethal" "neuromuscular junction,NMJ bouton,supernumerary,heat sensitive,neuromuscular junction | heat sensitive,ectopic,eye,neuromuscular junction & synapse,synapse | ectopic | heat sensitive,adult central nervous system,neuromuscular junction | temperature conditional,temperature conditional,dorsal medial muscle,adult brain,motor neuron" FBgn0002279 l(3)73Ad lethal (3) 73Ad http://flybase.net/reports/FBgn0002279.html gene l(3)std8 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0036503 CG13454 http://flybase.net/reports/FBgn0036503.html protein_coding_gene CG13454 16-Dec-15 2015_12 viable FBgn0046320 roX2-CES roX2 chromatin entry site http://flybase.net/reports/FBgn0046320.html region CES 16-Dec-15 2015_12 FBgn0052011 CR32011 http://flybase.net/reports/FBgn0052011.html pseudogene_attribute CG32011 CR32011 16-Dec-15 2015_12 FBgn0036112 CG14147 http://flybase.net/reports/FBgn0036112.html FBgn0047162 protein_coding_gene BcDNA:RE16005 CG14147 16-Dec-15 2015_12 viable FBgn0023042 l(2)46Ea lethal (2) 46Ea http://flybase.net/reports/FBgn0023042.html FBgn0019708 gene "unnamed, 24.15, P, Complementation group P, l(2)46CFt" 16-Dec-15 2015_12 "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037116 Als2 Amyotrophic lateral sclerosis 2 ortholog http://flybase.net/reports/FBgn0037116.html protein_coding_gene "0017112=Rab guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity" "0043087=regulation of GTPase activity, 0035011=melanotic encapsulation of foreign target, 0032483=regulation of Rab protein signal transduction" 0031982=vesicle "CG7158, dALS2" "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR003123=VPS9 domain, IPR003409=MORN motif" CG7158 16-Dec-15 2015_12 "ENSXETG00000012406(ALS2),ENSXETG00000003686(ALS2CL)" "ENSMUSG00000026024(Als2),ENSMUSG00000044037(Als2cl)" "ENSG00000003393(ALS2),ENSG00000178038(ALS2CL)" "viable,fertile,locomotor behavior defective,progressive,gravitaxis defective,visible,immune response defective" "NMJ bouton,mesothoracic tergum" FBgn0001504 l(1)10Db lethal (1) 10Db http://flybase.net/reports/FBgn0001504.html gene 16-Dec-15 2015_12 lethal FBgn0264432 CG43850 http://flybase.net/reports/FBgn0264432.html protein_coding_gene CG43850 16-Dec-15 2015_12 FBgn0051749 CG31749 http://flybase.net/reports/FBgn0051749.html protein_coding_gene 16-Dec-15 2015_12 DRSC22776 K -0.106948989 -0.13256047 -0.20011671 -0.142590586 -0.545266494 -2.382984487 FBgn0011455 ND-SGDH NADH dehydrogenase (ubiquinone) SGDH subunit http://flybase.net/reports/FBgn0011455.html FBgn0036256 protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0000302=response to reactive oxygen species, 0006120=mitochondrial electron transport, NADH to ubiquinone, 0008340=determination of adult lifespan" "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "NADH:ubiquinone oxidoreductase SGDH subunit, lethal (3) neo18, NISM, NADH-ubiquinone oxidoreductase SGDH subunit, NADH ubiquinone oxidoreductase SGDH, l(3)neo18, CG9762" "IPR019173=NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit" CG9762 16-Dec-15 2015_12 ENSDARG00000070824(LOC100332773) WBGene00016118(C25H3.9) ENSXETG00000007264(NDUFB5) ENSMUSG00000027673(Ndufb5) ENSG00000136521(NDUFB5) "lethal,recessive,stress response defective,aging defective,long lived,female,RU486 conditional,female semi-fertile,viable" FBgn0065835 l(2)SH0338 lethal (2) SH0338 http://flybase.net/reports/FBgn0065835.html gene l(2)SH2 0338 16-Dec-15 2015_12 "lethal,recessive" FBgn0083274 E(smoDN)2578 Enhancer of smoDN 2578 http://flybase.net/reports/FBgn0083274.html gene 16-Dec-15 2015_12 FBgn0003024 ov oval http://flybase.net/reports/FBgn0003024.html gene 16-Dec-15 2015_12 eye FBgn0267772 CR46103 http://flybase.net/reports/FBgn0267772.html non_protein_coding_gene CR46103 16-Dec-15 2015_12 FBgn0065937 l(2)SH0123 lethal (2) SH0123 http://flybase.net/reports/FBgn0065937.html gene l(2)SH2 0123 16-Dec-15 2015_12 "lethal,recessive" FBgn0259421 EP-686 http://flybase.net/reports/FBgn0259421.html gene 16-Dec-15 2015_12 visible wing FBgn0266161 CR44867 http://flybase.net/reports/FBgn0266161.html non_protein_coding_gene CR44867 16-Dec-15 2015_12 FBgn0016638 ER2-1 ER2-1 http://flybase.net/reports/FBgn0016638.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022308 l(1)K87.2 lethal (1) K87.2 http://flybase.net/reports/FBgn0022308.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051257 CG31257 http://flybase.net/reports/FBgn0051257.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025354 Tdc Tyrosine decarboxylase http://flybase.net/reports/FBgn0025354.html gene 0004837=tyrosine decarboxylase activity 0048148=behavioral response to cocaine "tyrosine decarboxylase, TDC" 16-Dec-15 2015_12 FBgn0266969 CR45420 http://flybase.net/reports/FBgn0266969.html non_protein_coding_gene lincRNA.452 CR45420 16-Dec-15 2015_12 FBgn0261641 CG42724 http://flybase.net/reports/FBgn0261641.html "FBgn0053097, FBgn0037438, FBgn0051367" protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006355=regulation of transcription, DNA-templated, 0006354=DNA-templated transcription, elongation, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0071011=precatalytic spliceosome" "CG33097, CG31367, CG15187" "IPR002713=FF domain, IPR001202=WW domain" CG42724 16-Dec-15 2015_12 "ENSDARG00000025314(tcerg1),ENSDARG00000030665" ENSXETG00000002324(TCERG1) ENSMUSG00000024498(Tcerg1) ENSG00000113649(TCERG1) """DRSC22275, DRSC12567"" " IE FBgn0262692 Su(VGlut)B8 http://flybase.net/reports/FBgn0262692.html gene B8 16-Dec-15 2015_12 FBgn0030040 CG15347 http://flybase.net/reports/FBgn0030040.html protein_coding_gene IPR008472=Domain of unknown function DUF753 CG15347 16-Dec-15 2015_12 viable FBgn0051895 tRNA:CR31895 transfer RNA:CR31895 http://flybase.net/reports/FBgn0051895.html FBgn0060234 tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31895, tRNA:F:GAA:AE002690, AE002690.trna5-PheGAA, Phe-tRNA, chr2L.trna14-PheGAA" CR31895 16-Dec-15 2015_12 FBgn0030160 CG9691 http://flybase.net/reports/FBgn0030160.html FBgn0062958 protein_coding_gene "BcDNA:RH12290, CT27394" CG9691 16-Dec-15 2015_12 viable FBgn0052251 Claspin Claspin http://flybase.net/reports/FBgn0052251.html FBgn0035531 protein_coding_gene 0033314=mitotic DNA replication checkpoint 0005634=nucleus "Claspin, CG1326, CG32251" IPR024146=Claspin CG32251 16-Dec-15 2015_12 ENSXETG00000009662(CLSPN) ENSMUSG00000042489(Clspn) ENSG00000092853(CLSPN) "chemical sensitive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially lethal - majority die,viable,fertile" FBgn0060560 l(3)S096901a lethal (3) S096901a http://flybase.net/reports/FBgn0060560.html gene 0969/01 16-Dec-15 2015_12 lethal FBgn0061021 l(3)S025255 lethal (3) S025255 http://flybase.net/reports/FBgn0061021.html gene 0252/55 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0263074 BG01354 http://flybase.net/reports/FBgn0263074.html gene 0002121=inter-male aggressive behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0005349 stuck stuck http://flybase.net/reports/FBgn0005349.html gene 0007620=copulation sk 16-Dec-15 2015_12 FBgn0011474 Set8 SET domain containing 8 http://flybase.net/reports/FBgn0011474.html FBgn0038222 protein_coding_gene 0042799=histone methyltransferase activity (H4-K20 specific) "0030261=chromosome condensation, 0016571=histone methylation, 0000077=DNA damage checkpoint, 0035067=negative regulation of histone acetylation, 0034771=histone H4-K20 monomethylation" 0005700=polytene chromosome "dSet8, Pr-set-7, dPR-Set7, PR-Set7, PRSET7, pr-set7, CG3307, PR/SET07, l(3)neo41, pr-Set7, PR-SET7, Set7, Set8, SET8, dSET8" "IPR001214=SET domain, IPR016858=Histone H4-K20 methyltransferase" CG3307 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,suppressor of variegation,dominant,non-suppressor of variegation,non-enhancer of variegation,mitotic cell cycle defective,viable,visible" "eye,wing margin,macrochaeta,melanotic mass,embryonic/larval cuticle,embryonic/larval digestive system,embryonic/larval brain,ventral thoracic disc,wing disc,neuroblast,chromosome,condensed chromosome,embryonic/larval tracheal system,mesothoracic tergum" FBgn0265499 CR44368 http://flybase.net/reports/FBgn0265499.html non_protein_coding_gene CR44368 16-Dec-15 2015_12 FBgn0044866 MMS-1 MMS-1 http://flybase.net/reports/FBgn0044866.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0034532 CG13436 http://flybase.net/reports/FBgn0034532.html protein_coding_gene IPR021897=Protein of unknown function DUF3508 CG13436 16-Dec-15 2015_12 ENSDARG00000021997(zgc:109719) ENSXETG00000006172(C6orf165) ENSMUSG00000028294(1700003M02Rik) ENSG00000213204(C6orf165) FBgn0267813 CR46138 http://flybase.net/reports/FBgn0267813.html non_protein_coding_gene CR46138 16-Dec-15 2015_12 FBgn0044078 E(rst)H74 E(rst)H74 http://flybase.net/reports/FBgn0044078.html gene 0001745=compound eye morphogenesis H74 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0053378 5SrRNA:CR33378 5SrRNA:CR33378 http://flybase.net/reports/FBgn0053378.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33378 CR33378 16-Dec-15 2015_12 FBgn0051559 CG31559 http://flybase.net/reports/FBgn0051559.html "FBgn0037403, FBgn0037404" protein_coding_gene "0009055=electron carrier activity, 0015035=protein disulfide oxidoreductase activity" 0045454=cell redox homeostasis "CG11461, CG15584, 31559" "IPR012336=Thioredoxin-like fold, IPR002109=Glutaredoxin" CG31559 16-Dec-15 2015_12 ENSDARG00000053692 ENSMUSG00000068082(Grxcr1) "ENSG00000204928(GRXCR2),ENSG00000215203(GRXCR1)" viable FBgn0267769 CR46100 http://flybase.net/reports/FBgn0267769.html non_protein_coding_gene CR46100 16-Dec-15 2015_12 FBgn0053199 CG33199 http://flybase.net/reports/FBgn0053199.html FBgn0064765 protein_coding_gene CG33199 16-Dec-15 2015_12 "viable,fertile" FBgn0035512 Cpr64Ac Cuticular protein 64Ac http://flybase.net/reports/FBgn0035512.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr64Ac, CG15008" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG15008 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000120 Arr1 Arrestin 1 http://flybase.net/reports/FBgn0000120.html protein_coding_gene 0002046=opsin binding "0016060=metarhodopsin inactivation, 0045494=photoreceptor cell maintenance, 0007602=phototransduction, 0016059=deactivation of rhodopsin mediated signaling, 0006897=endocytosis" "0005737=cytoplasm, 0016028=rhabdomere" "arr1, Dro.-Arr.I, ArrA, unnamed, DS-Ag, arrestin1, Dmarrestin, Drosophila Arrestin, DA, arrestin, arrestin 1, CG5711, Arrestin, Arrestin1, FBgn0000120, Arr, PRII, Arrestin A, ARR1, Phosrestin-II, DAI, DmArr1, 3H10" "IPR014756=Immunoglobulin E-set, IPR000698=Arrestin, IPR014753=Arrestin, N-terminal, IPR014752=Arrestin, C-terminal, IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain, IPR017864=Arrestin, conserved site" CG5711 16-Dec-15 2015_12 " adult stage , spermatogenesis && adult stage , adult stage | early , pupal stage | late " " photoreceptor cell &&of ocellus

, testis

, photoreceptor cell &&of retina

" adult stage rhabdomere

"smell perception defective,dominant,increased cell death,viable" "ommatidial cluster & endocytic vesicle,rhabdomere,eye photoreceptor cell" FBgn0005237 l(3)R52 lethal of Roberts 52 http://flybase.net/reports/FBgn0005237.html gene l(3)B52 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0005406 l(1)10Dd lethal (1) 10Dd http://flybase.net/reports/FBgn0005406.html gene 16-Dec-15 2015_12 lethal FBgn0031753 CG13999 http://flybase.net/reports/FBgn0031753.html protein_coding_gene 0042384=cilium assembly 0005929=cilium IPR024133=Transmembrane protein 138 CG13999 16-Dec-15 2015_12 WBGene00008643(F10B5.9) ENSXETG00000008824(TGas052n20.1) ENSMUSG00000024666(Tmem138) ENSG00000149483(TMEM138) viable FBgn0002011 l(2)36Fd lethal (2) 36Fd http://flybase.net/reports/FBgn0002011.html gene "36Fd, l(2)E51, Fd" 16-Dec-15 2015_12 lethal FBgn0011075 l(1)Q28 lethal (1) Q28 http://flybase.net/reports/FBgn0011075.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0025770 l(3)89Bu lethal (3) 89Bu http://flybase.net/reports/FBgn0025770.html gene l(3)M1511 16-Dec-15 2015_12 "lethal,recessive" FBgn0265978 CR44757 http://flybase.net/reports/FBgn0265978.html non_protein_coding_gene CR44757 16-Dec-15 2015_12 FBgn0031392 AIF Apoptosis inducing factor http://flybase.net/reports/FBgn0031392.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity, 0003677=DNA binding, 0046983=protein dimerization activity" "0045454=cell redox homeostasis, 0050832=defense response to fungus, 0010623=developmental programmed cell death, 0042775=mitochondrial ATP synthesis coupled electron transport" 0005739=mitochondrion "CG7263, SD03428p, aif, AIF, DmAIF, Apoptosis Inducing Factor" "IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR029324=Mitochondrial apoptosis-inducing factor, C-terminal domain, IPR004099=Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR016156=FAD/NAD-linked reductase, dimerisation domain" CG7263 16-Dec-15 2015_12 ENSDARG00000058088(pdcd8) WBGene00006937(wah-1) ENSXETG00000018186(pdcd8) ENSMUSG00000036932(Aifm1) ENSG00000156709(AIFM1) "immune response defective,dominant,small body,decreased cell death,lethal - all die before end of larval stage,some die during larval stage,lethal,partially,visible,increased cell death,viable" "hemocyte,plasmatocyte,ventral nerve cord,Bolwig organ,eye,ommatidium,eye disc,mesothoracic bristle,trichogen cell" FBgn0036203 Muc68D Mucin 68D http://flybase.net/reports/FBgn0036203.html "FBgn0045905, FBgn0045906" protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane, 0005201=extracellular matrix structural constituent" 0006030=chitin metabolic process "0005576=extracellular region, 0031012=extracellular matrix" "anon-WO0153538.48, CG6004, Muc68D, anon-WO0153538.47" IPR002557=Chitin binding domain CG6004 16-Dec-15 2015_12 viable FBgn0067656 sd-11 sd-11 http://flybase.net/reports/FBgn0067656.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 11 16-Dec-15 2015_12 "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0011006 l(3)s1629b lethal (3) s1629b http://flybase.net/reports/FBgn0011006.html gene l(3)s1629 16-Dec-15 2015_12 "lethal,recessive" FBgn0030675 CG8191 http://flybase.net/reports/FBgn0030675.html protein_coding_gene CG8191 16-Dec-15 2015_12 FBgn0266516 s-563.1 http://flybase.net/reports/FBgn0266516.html gene 16-Dec-15 2015_12 FBgn0001816 l(1)P1 lethal (1) P1 http://flybase.net/reports/FBgn0001816.html gene 16-Dec-15 2015_12 "lethal,male,recessive,cold sensitive,viable,female" FBgn0065720 l(2)SH0570 lethal (2) SH0570 http://flybase.net/reports/FBgn0065720.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035102 CG7049 http://flybase.net/reports/FBgn0035102.html protein_coding_gene "IPR016187=C-type lectin fold, IPR005532=Sulfatase-modifying factor enzyme" CG7049 16-Dec-15 2015_12 ENSDARG00000044203(zgc:136465) ENSXETG00000005149(sumf1) ENSMUSG00000030101(Sumf1) ENSG00000144455(SUMF1) viable FBgn0033112 Spn42Db Serpin 42Db http://flybase.net/reports/FBgn0033112.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0010951=negative regulation of endopeptidase activity, 0045861=negative regulation of proteolysis, 0030162=regulation of proteolysis" 0005615=extracellular space CG9454 "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG9454 16-Dec-15 2015_12 ENSXETG00000022866(SERPINI1) "ENSMUSG00000027834(Serpini1),ENSMUSG00000034139(Serpini2)" "ENSG00000163536(SERPINI1),ENSG00000114204(SERPINI2)" viable FBgn0267702 CR46035 http://flybase.net/reports/FBgn0267702.html non_protein_coding_gene CR46035 16-Dec-15 2015_12 FBgn0267453 CR45803 http://flybase.net/reports/FBgn0267453.html non_protein_coding_gene CR45803 16-Dec-15 2015_12 FBgn0085733 CR40375 http://flybase.net/reports/FBgn0085733.html "FBan0040375, FBgn0062448, FBgn0058375" non_protein_coding_gene BcDNA:RE28552 16-Dec-15 2015_12 FBgn0027996 l(3)S125015b lethal (3) S125015b http://flybase.net/reports/FBgn0027996.html gene "l(3)S125015, 1250/15" 16-Dec-15 2015_12 "some die during larval stage,lethal,recessive,lethal - all die before end of larval stage" FBgn0031769 CG9135 http://flybase.net/reports/FBgn0031769.html protein_coding_gene 0005085=guanyl-nucleotide exchange factor activity "0000278=mitotic cell cycle, 0034260=negative regulation of GTPase activity, 0051301=cell division, 0007032=endosome organization" 0005875=microtubule associated complex "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR028641=Protein RCC2" CG9135 16-Dec-15 2015_12 ENSDARG00000011510(rcc2) ENSXETG00000014793(RCC2) ENSMUSG00000040945(Rcc2) ENSG00000179051(RCC2) "viable,fertile,body color defective" mesothoracic tergum FBgn0051075 CG31075 http://flybase.net/reports/FBgn0051075.html FBgn0039468 protein_coding_gene 0004029=aldehyde dehydrogenase (NAD) activity "0055114=oxidation-reduction process, 0006090=pyruvate metabolic process" "0005739=mitochondrion, 0005759=mitochondrial matrix" "CG6309, 150697_at, CT19744" "IPR016160=Aldehyde dehydrogenase, cysteine active site, IPR016161=Aldehyde/histidinol dehydrogenase, IPR015590=Aldehyde dehydrogenase domain, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR029510=Aldehyde dehydrogenase, glutamic acid active site, IPR016163=Aldehyde dehydrogenase, C-terminal" CG31075 16-Dec-15 2015_12 "YER073W(ALD5),YOR374W(ALD4),YPL061W(ALD6)" "viable,fertile" FBgn0010649 l(2)08492 lethal (2) 08492 http://flybase.net/reports/FBgn0010649.html FBgn0033213 gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263341 CR43422 http://flybase.net/reports/FBgn0263341.html non_protein_coding_gene CR43422 16-Dec-15 2015_12 FBgn0265080 CR44191 http://flybase.net/reports/FBgn0265080.html non_protein_coding_gene CR44191 16-Dec-15 2015_12 FBgn0069438 EP2190 EP2190 http://flybase.net/reports/FBgn0069438.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0264561 Glg1 Golgi complex-localized glycoprotein 1 http://flybase.net/reports/FBgn0264561.html "FBgn0053214, FBgn0037088, FBgn0037089, FBgn0037091, FBgn0043024" protein_coding_gene "0016021=integral component of membrane, 0000138=Golgi trans cisterna, 0000137=Golgi cis cisterna, 0000139=Golgi membrane, 0005797=Golgi medial cisterna, 0012505=endomembrane system" "gp120, CG33214, p120kD, GLG1, CG7195, 120-kDa, dGLG1, d120kd, 120 kDa, DG13, unnamed, CG7193, d120, p120-Golgi, CG7190, d120kD, p120, 120KD, Golgi 120-kDa protein, 120kDa, Golgi complex-localized glycoprotein-1" "IPR001893=Cysteine-rich Golgi apparatus protein 1 repeat, IPR017873=Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote" CG33214 16-Dec-15 2015_12 WBGene00008800(F14E5.2) ENSMUSG00000003316(Glg1) ENSG00000090863(GLG1) FBgn0267285 CR45721 http://flybase.net/reports/FBgn0267285.html non_protein_coding_gene CR45721 16-Dec-15 2015_12 FBgn0003237 Rev Revolute http://flybase.net/reports/FBgn0003237.html gene "Curved of Krivshenko, C-K" 16-Dec-15 2015_12 FBgn0035445 CG12014 http://flybase.net/reports/FBgn0035445.html FBgn0027697 protein_coding_gene 0004423=iduronate-2-sulfatase activity 0008152=metabolic process anon-EST:Posey282 "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR024607=Sulfatase, conserved site, IPR000917=Sulfatase, IPR017850=Alkaline-phosphatase-like, core domain" CG12014 16-Dec-15 2015_12 ENSDARG00000071699(ids) ENSMUSG00000035847(Ids) ENSG00000010404(IDS) viable DRSC08222 K 0.844550724 0.405215387 0.116084204 -0.014748685 0.405921189 1.876709539 FBgn0265184 CG44249 http://flybase.net/reports/FBgn0265184.html "FBgn0259142, FBgn0034686, FBgn0050327" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" "0000398=mRNA splicing, via spliceosome" "0005689=U12-type spliceosomal complex, 0034693=U11/U12 snRNP, 0005693=U12 snRNP" "CG42257, cg11478, 65K, CG30327, CG11478" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG44249 16-Dec-15 2015_12 FBgn0034726 Mes4 Mesoderm-expressed 4 http://flybase.net/reports/FBgn0034726.html FBgn0063190 protein_coding_gene "0043565=sequence-specific DNA binding, 0003887=DNA-directed DNA polymerase activity, 0046982=protein heterodimerization activity" "0006974=cellular response to DNA damage stimulus, 0006260=DNA replication" "0008622=epsilon DNA polymerase complex, 0005622=intracellular" "BcDNA:GM21739, 11301, NF-YC-like, CG11301, NF-Yc, Mes4, MES4" "IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072=Histone-fold" CG11301 16-Dec-15 2015_12 ENSDARG00000013016(zgc:110337) ENSXETG00000014422(pole4) ENSMUSG00000030042(Pole4) ENSG00000115350(POLE4) " embryonic stage | gastrula , embryonic stage | syncytial blastoderm , embryonic stage | stage 5 " " mesoderm anlage | pair rule

, mesoderm anlage

" "viable,visible,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing disc" FBgn0060812 l(3)S054507b lethal (3) S054507b http://flybase.net/reports/FBgn0060812.html gene 0545/07 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0022373 Pt-2 Larval protein-2 http://flybase.net/reports/FBgn0022373.html gene 16-Dec-15 2015_12 FBgn0014186 gyn-3 gyn-3 http://flybase.net/reports/FBgn0014186.html gene "unnamed, gynogenetic-3" 16-Dec-15 2015_12 FBgn0000152 Axs Abnormal X segregation http://flybase.net/reports/FBgn0000152.html "FBtr0074372, FBpp0074146" protein_coding_gene "0032837=distributive segregation, 0016321=female meiosis chromosome segregation, 0000212=meiotic spindle organization" "0005819=spindle, 0005640=nuclear outer membrane, 0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005938=cell cortex" "axs, abnormal X segregation, Aberrant X segregation, CG9703" IPR007632=Anoctamin CG9703 16-Dec-15 2015_12 "ENSDARG00000057736(zgc:114140),ENSDARG00000018159(zgc:153923)" YBR086C(IST2) ENSXETG00000022024(ANO10) ENSMUSG00000037949(Ano10) ENSG00000160746(ANO10) "meiotic cell cycle defective,female,dominant,semidominant,recessive,viable,visible" "meiosis & nuclear chromosome | female,meiosis & nuclear chromosomenos.UTR.THsimVP16,meiosis & nuclear chromosome & spindlenos.UTR.THsimVP16,trichogen cell,mesothoracic tergum" FBgn0002737 M(G6PD) Modifier of Gpdh http://flybase.net/reports/FBgn0002737.html gene "L-a[Zw], Modifier-of-Zwischenferment, Low activity-auxocompensation for G-6-PD, M[Zw], Modified glucose-6-phosphate dehydrogenase" 16-Dec-15 2015_12 FBgn0051604 tRNA:CR31604 transfer RNA:CR31604 http://flybase.net/reports/FBgn0051604.html FBgn0011843 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31604, tRNA:asp2:29E, tRNA:D2:29E, transfer RNA:asp2:29E, tRNA[[Asp]], chr2L.trna31-AspGTC, tRNA[Asp-GTC]" CR31604 16-Dec-15 2015_12 FBgn0067330 2F26 2F26 http://flybase.net/reports/FBgn0067330.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing vein,ectopic,somatic clone,wing,wing vein L3" FBgn0004502 fs(1)ë_a7 female sterile (1) ë_a7 http://flybase.net/reports/FBgn0004502.html gene 16-Dec-15 2015_12 FBgn0038017 CG4115 http://flybase.net/reports/FBgn0038017.html protein_coding_gene 0030246=carbohydrate binding "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin" CG4115 16-Dec-15 2015_12 "viable,fertile" FBgn0014024 Rnp4F RNA-binding protein 4F http://flybase.net/reports/FBgn0014024.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" "0007417=central nervous system development, 0006396=RNA processing" 0005622=intracellular "rnp-4f, Rnp-4F, 4F-rnp, splicing assembly factor rnp-4f, 4f-rnp, CG3312, RNP-4F" "IPR003107=HAT (Half-A-TPR) repeat, IPR000504=RNA recognition motif domain, IPR008669=LSM-interacting domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG3312 16-Dec-15 2015_12 ENSDARG00000008032(sart3) ENSMUSG00000018974(Sart3) ENSG00000075856(SART3) " embryonic stage | stage 4 , embryonic stage | stage 4-16 , embryonic stage | stage 14-16 , embryonic stage , embryonic stage | stage 14 , adult stage , embryonic stage&&larval stage&&adult stage , oogenesis stage | stage >=S10A , oogenesis stage | stage >=S6 , embryonic stage | stage 13 , embryonic stage | stage 10 , pupal stage " " pole cell

, ventral nerve cord commissure

, epidermis

, muscle system | restricted

, ventral nerve cord | dorsal

segmentally repeated , adult head

, embryonic/larval foregut

, oocyte

, embryonic central nervous system

, proctodeum

, nurse cell

, stomodeum

, longitudinal connective

, embryonic/larval hindgut

" "wild-type,lethal,recessive,viable" FBgn0051013 CG31013 http://flybase.net/reports/FBgn0051013.html FBgn0039793 protein_coding_gene "0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum CG9713 "IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain" CG31013 16-Dec-15 2015_12 viable FBgn0003172 Pw Pointed wing http://flybase.net/reports/FBgn0003172.html gene "Pt, Pointed" 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0032727 CG10623 http://flybase.net/reports/FBgn0032727.html protein_coding_gene "0016205=selenocysteine methyltransferase activity, 0008898=S-adenosylmethionine-homocysteine S-methyltransferase activity" selenocysteine methyltransferase IPR003726=Homocysteine-binding domain CG10623 16-Dec-15 2015_12 ENSDARG00000034430(zgc:172121) "YPL273W(SAM4),YLL062C(MHT1)" WBGene00020491(T13G4.4) ENSXETG00000025468(BC059753.1) "ENSMUSG00000069324,ENSMUSG00000082293,ENSMUSG00000066252,ENSMUSG00000042118(Bhmt2)" "ENSG00000145692(BHMT),ENSG00000132840(BHMT2)" viable FBgn0011860 tRNA:G3:22BCb transfer RNA:gly3:22BCb http://flybase.net/reports/FBgn0011860.html "FBgn0003776, FBgn0051945, FBgn0060225" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Gly-GCC], chr2L.trna4-GlyGCC, tRNA:G:GCC:AE002638-b, CR31945, tRNA:gly3:22BCb, AE002638.trna11-GlyGCC" CR31945 16-Dec-15 2015_12 FBgn0036587 CG4950 http://flybase.net/reports/FBgn0036587.html protein_coding_gene CT15890 "IPR026906=Leucine rich repeat 5, IPR001611=Leucine-rich repeat" CG4950 16-Dec-15 2015_12 viable FBgn0035876 Pex2 Peroxin 2 http://flybase.net/reports/FBgn0035876.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0007112=male meiosis cytokinesis, 0007286=spermatid development, 0048137=spermatocyte division, 0000209=protein polyubiquitination, 0007285=primary spermatocyte growth, 0007031=peroxisome organization, 0016558=protein import into peroxisome matrix" "0005778=peroxisomal membrane, 0005777=peroxisome" "pex2, peroxin 2, PEX2, CG7081, DmelPex2" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR006845=Pex, N-terminal, IPR001841=Zinc finger, RING-type" CG7081 16-Dec-15 2015_12 ENSDARG00000062421 WBGene00004192(prx-2) ENSXETG00000017165(pxmp3) ENSMUSG00000040374(Pxmp3) ENSG00000164751(PEX2) "lethal,viable,male sterile,female semi-sterile,developmental rate defective,cytokinesis defective,meiotic cell cycle defective" "spermatid,testis" FBgn0038082 CG5724 http://flybase.net/reports/FBgn0038082.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG5724 16-Dec-15 2015_12 "WBGene00007073(ugt-2),WBGene00007072(ugt-1),WBGene00013903(ugt-3),WBGene00020592(ugt-12),WBGene00020594(ugt-10),WBGene00020593(ugt-11),WBGene00020587(ugt-9),WBGene00019234(ugt-8),WBGene00019232(ugt-13),WBGene00019235(H23N18.4),WBGene00019233(ugt-14)" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell FBgn0001017 fs(3)A8 female sterile (3) A8 http://flybase.net/reports/FBgn0001017.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0259652 B0462 http://flybase.net/reports/FBgn0259652.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,antennal segment,arista,proboscis" FBgn0082971 snoRNA:ë¬28S-3316b snoRNA:ë¬28S-3316b http://flybase.net/reports/FBgn0082971.html snoRNA_gene "CR34548, psi28S-3316b, Psi28S-3316b" CR34548 16-Dec-15 2015_12 FBgn0262845 CG43209 http://flybase.net/reports/FBgn0262845.html protein_coding_gene DMG4-MB6.chr2R.33.028 CG43209 16-Dec-15 2015_12 FBgn0250906 Pgk Phosphoglycerate kinase http://flybase.net/reports/FBgn0250906.html "FBgn0003075, FBgn0014416, FBgn0013525" protein_coding_gene "0004618=phosphoglycerate kinase activity, 0005524=ATP binding" "0007520=myoblast fusion, 0007268=synaptic transmission, 0016310=phosphorylation, 0006096=glycolytic process, 0046716=muscle cell cellular homeostasis, 0007525=somatic muscle development" "0031430=M band, 0005737=cytoplasm, 0030018=Z disc" "l(2)23AB3, ESTS:169C9S, CG3127, phosphoglycerokinase, anon-sts18, 169C9S, pgk, lethal (2) 23AB3, phosphoglycerate kinase, l(2)23Ac, PGK" "IPR001576=Phosphoglycerate kinase, IPR015824=Phosphoglycerate kinase, N-terminal, IPR015901=Phosphoglycerate kinase, C-terminal, IPR015911=Phosphoglycerate kinase, conserved site" CG3127 16-Dec-15 2015_12 ENSDARG00000054191(pgk1) YCR012W(PGK1) WBGene00020185(pgk-1) ENSXETG00000007447() "ENSMUSG00000062070(Pgk1),ENSMUSG00000031233(Pgk2)" "ENSG00000102144(PGK1),ENSG00000170950(PGK2)" FBgn0041242 Gr47a Gustatory receptor 47a http://flybase.net/reports/FBgn0041242.html FBgn0033514 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "unnamed, 47A1, Gr47A, Gustatory receptor 47A.1, GR47A.1, Gr47A1, CG12906, 47A.1" IPR013604=7TM chemoreceptor CG12906 16-Dec-15 2015_12 viable FBgn0260505 Pkc53E::Rok http://flybase.net/reports/FBgn0260505.html engineered_fusion_gene "Rok-53E, Pkc53E::rok" 16-Dec-15 2015_12 FBgn0020803 ms(3)C131 ms(3)C131 http://flybase.net/reports/FBgn0020803.html gene 3-C131 16-Dec-15 2015_12 "chemical sensitive,recessive,male sterile" FBgn0030105 CG15369 http://flybase.net/reports/FBgn0030105.html protein_coding_gene 0004869=cysteine-type endopeptidase inhibitor activity IPR000010=Cystatin domain CG15369 16-Dec-15 2015_12 "viable,fertile" FBgn0016013 Faa Fumarylacetoacetase http://flybase.net/reports/FBgn0016013.html FBgn0035494 protein_coding_gene 0004334=fumarylacetoacetase activity 0009072=aromatic amino acid family metabolic process "dfaa, l(3)64Al, CG14993, l(3)SH11" "IPR005959=Fumarylacetoacetase, IPR015377=Fumarylacetoacetase, N-terminal, IPR011234=Fumarylacetoacetase, C-terminal-related" CG14993 16-Dec-15 2015_12 ENSDARG00000039743(fah) WBGene00019620(fah-1) ENSXETG00000024287(FAH) ENSMUSG00000030630(Fah) ENSG00000103876(FAH) "wild-type,lethal,recessive,viable" FBgn0051334 tRNA:CR31334 transfer RNA:CR31334 http://flybase.net/reports/FBgn0051334.html "FBgn0011990, FBgn0023420, FBgn0060040" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033440=ACG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Thr][[4]], tRNA[Thr][[3]], tRNA:thr4:93A, tRNA:T3:93AB, tRNA[[Thr]], transfer RNA:thr4:93A, chr3R.trna30-ThrCGT, CR31334, AE002708.trna24-ThrCGT, tRNA:T:CGT:AE002708-b, tRNA:T4:93A" CR31334 16-Dec-15 2015_12 FBgn0039576 UQCR-14L Ubiquinol-cytochrome c reductase 14 kDa subunit-like http://flybase.net/reports/FBgn0039576.html protein_coding_gene 0008121=ubiquinol-cytochrome-c reductase activity "0006122=mitochondrial electron transport, ubiquinol to cytochrome c, 0034551=mitochondrial respiratory chain complex III assembly, 0000302=response to reactive oxygen species, 0008340=determination of adult lifespan" 0005750=mitochondrial respiratory chain complex III "Ubiquinol-cytochrome C reductase complex 14 kDa protein, Complex III, Ubiquinol-cytochrome c reductase 14 kDa protein, CG17856, UCR6" IPR003197=Cytochrome b-c1 complex subunit 7 CG17856 16-Dec-15 2015_12 ENSDARG00000011146(uqcrb) YDR529C(QCR7) WBGene00020181(T02H6.11) "ENSMUSG00000021520(Uqcrb),ENSMUSG00000021741(Gm5457)" ENSG00000156467(UQCRB) "lethal - all die before end of larval stage,some die during larval stage,long lived,female,RU486 conditional,female semi-fertile,stress response defective,lethal,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval brain,trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0004200 l(3)84Db lethal (3) 84Db http://flybase.net/reports/FBgn0004200.html gene 16-Dec-15 2015_12 "lethal,recessive,visible" male genitalia FBgn0020649 Hsp64 Heat shock protein 64 http://flybase.net/reports/FBgn0020649.html gene 0009408=response to heat HSP64 16-Dec-15 2015_12 FBgn0265369 CR44310 http://flybase.net/reports/FBgn0265369.html non_protein_coding_gene CR44310 16-Dec-15 2015_12 FBgn0010457 l(2)00064 lethal (2) 00064 http://flybase.net/reports/FBgn0010457.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0265208 T:SS-Lsp1ë_ Signal sequence of Lsp1ë_ http://flybase.net/reports/FBgn0265208.html engineered_tag 16-Dec-15 2015_12 FBgn0035596 CG10677 http://flybase.net/reports/FBgn0035596.html FBgn0046390 protein_coding_gene anon-WO0172774.40 16-Dec-15 2015_12 FBgn0038078 CG14391 http://flybase.net/reports/FBgn0038078.html FBgn0063311 protein_coding_gene BcDNA:AT22529 CG14391 16-Dec-15 2015_12 viable FBgn0263768 CR43685 http://flybase.net/reports/FBgn0263768.html non_protein_coding_gene lincRNA.703 CR43685 16-Dec-15 2015_12 FBgn0262307 mir-990 mir-990 stem loop http://flybase.net/reports/FBgn0262307.html miRNA_gene "miR-990, dme-mir-990, CR43014" CR43014 16-Dec-15 2015_12 viable FBgn0040813 Nplp2 Neuropeptide-like precursor 2 http://flybase.net/reports/FBgn0040813.html FBgn0062965 protein_coding_gene 0005184=neuropeptide hormone activity "0006959=humoral immune response, 0007218=neuropeptide signaling pathway" "0005615=extracellular space, 0005576=extracellular region" "NPLP 2, NPLP2, neuropeptide-like precursor 2, NEF, CG11051, BcDNA:RH08410, nplp2, NEF peptide" CG11051 16-Dec-15 2015_12 viable FBgn0069152 mcl(3)Z3320 mcl(3)Z3320 http://flybase.net/reports/FBgn0069152.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0015403 l(1)10Bp lethal (1) 10Bp http://flybase.net/reports/FBgn0015403.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262825 CR43196 http://flybase.net/reports/FBgn0262825.html non_protein_coding_gene CG43196 CR43196 16-Dec-15 2015_12 FBgn0085675 CG41536 http://flybase.net/reports/FBgn0085675.html FBan0041536 protein_coding_gene 16-Dec-15 2015_12 FBgn0011805 l(3)rQ303 lethal (3) rQ303 http://flybase.net/reports/FBgn0011805.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal,recessive,rescuable maternal effect" "embryonic/first instar larval cuticle,amnioserosa" FBgn0065088 snmRNA:641 small non-messenger RNA 641 http://flybase.net/reports/FBgn0065088.html FBgn0053683 non_protein_coding_gene "CR33683, Dm-641" CR33683 16-Dec-15 2015_12 FBgn0044864 MMS-3 MMS-3 http://flybase.net/reports/FBgn0044864.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0084043 CG41483 http://flybase.net/reports/FBgn0084043.html FBan0041483 protein_coding_gene 16-Dec-15 2015_12 FBgn0262876 CG43231 http://flybase.net/reports/FBgn0262876.html protein_coding_gene CG43231 16-Dec-15 2015_12 FBgn0015433 l(1)4Ca lethal (1) 4Ca http://flybase.net/reports/FBgn0015433.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267806 CR46131 http://flybase.net/reports/FBgn0267806.html non_protein_coding_gene CR46131 16-Dec-15 2015_12 FBgn0027872 rdgBë_ rdgBë_ http://flybase.net/reports/FBgn0027872.html protein_coding_gene 0008526=phosphatidylinositol transporter activity "0006810=transport, 0007165=signal transduction" 0005737=cytoplasm "RdgB-beta, CG17818, RdgBbeta, BcDNA:LD14189, BcDNA.LD14189, DrdgBbeta" "IPR001666=Phosphatidylinositol transfer protein, IPR023393=START-like domain" CG17818 16-Dec-15 2015_12 ENSDARG00000022807(zgc:101640) "ENSXETG00000009163(),ENSXETG00000001586(PITPNC1)" ENSMUSG00000040430(Pitpnc1) ENSG00000154217(PITPNC1) viable FBgn0035713 velo veloren http://flybase.net/reports/FBgn0035713.html protein_coding_gene "0016929=SUMO-specific protease activity, 0008234=cysteine-type peptidase activity" "0021952=central nervous system projection neuron axonogenesis, 0060997=dendritic spine morphogenesis, 0060548=negative regulation of cell death, 0007411=axon guidance, 0016926=protein desumoylation, 0006508=proteolysis" 0005634=nucleus "verloren, CG10107" "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG10107 16-Dec-15 2015_12 ENSXETG00000003609(senp6) ENSMUSG00000052917(Senp7) ENSG00000112701(SENP6) "lethal,neuroanatomy defective,somatic clone,partially lethal - majority die,visible" "adult antennal lobe projection neuron DL1 adPN,somatic clone,antennal lobe glomerulus DL1,dendrite | somatic clone,mesothoracic tergum" DRSC08841 IK -0.236035971 2.018281599 0.418522679 0.756669789 -2.311660769 1.007875968 FBgn0083263 E(smoDN)548 Enhancer of smoDN 548 http://flybase.net/reports/FBgn0083263.html gene 16-Dec-15 2015_12 FBgn0035203 CG9149 http://flybase.net/reports/FBgn0035203.html protein_coding_gene 0003988=acetyl-CoA C-acyltransferase activity 0006635=fatty acid beta-oxidation 0005777=peroxisome ACAT "IPR020617=Thiolase, C-terminal, IPR020616=Thiolase, N-terminal, IPR020615=Thiolase, acyl-enzyme intermediate active site, IPR020610=Thiolase, active site, IPR016039=Thiolase-like, IPR002155=Thiolase, IPR020613=Thiolase, conserved site" CG9149 16-Dec-15 2015_12 ENSDARG00000007127(acat2) ENSXETG00000021174(acat2) "ENSMUSG00000023832(Acat2),ENSMUSG00000062480(Acat3)" ENSG00000120437(ACAT2) "viable,fertile" DRSC08630 I -0.054740627 1.629565541 -0.063521707 0.303186237 0.075826385 -0.202413332 FBgn0029031 l(2)R89 lethal (2) R89 http://flybase.net/reports/FBgn0029031.html gene R89 16-Dec-15 2015_12 "lethal,recessive" FBgn0035397 CG11486 http://flybase.net/reports/FBgn0035397.html protein_coding_gene "0044822=poly(A) RNA binding, 0004672=protein kinase activity, 0005515=protein binding" "0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0006468=protein phosphorylation, 0006397=mRNA processing" "0031251=PAN complex, 0005737=cytoplasm" "PAN3, polyA-nuclease related" "IPR030844=PAB-dependent poly(A)-specific ribonuclease subunit PAN3, IPR011009=Protein kinase-like domain" CG11486 16-Dec-15 2015_12 ENSDARG00000031637(zgc:171628) YKL025C(PAN3) WBGene00014015(ZK632.7) ENSXETG00000011794(PAN3) ENSMUSG00000029647(Pan3) ENSG00000152520(PAN3) "viable,fertile,neuroanatomy defective" "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0265574 Cdc5 Cell division cycle 5 ortholog http://flybase.net/reports/FBgn0265574.html "FBgn0035136, FBgn0025183" protein_coding_gene "0003677=DNA binding, 0044822=poly(A) RNA binding" "0000398=mRNA splicing, via spliceosome, 0051298=centrosome duplication" "0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex, 0000974=Prp19 complex, 0005634=nucleus, 0071011=precatalytic spliceosome" "cdc5, cef1, cdc5-like, Cdc5Dm, CG6905" "IPR021786=Pre-mRNA splicing factor component Cdc5p/Cef1, IPR017930=Myb domain, IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like" CG6905 16-Dec-15 2015_12 ENSDARG00000043797(cdc5l) WBGene00008386(D1081.8) ENSXETG00000007885(CDC5L) ENSMUSG00000023932(Cdc5l) ENSG00000096401(CDC5L) DRSC26879 K -0.429861821 0.152921757 -0.934409282 0.526976763 0.258285986 2.205826794 FBgn0266977 CG45428 http://flybase.net/reports/FBgn0266977.html protein_coding_gene CG45428 16-Dec-15 2015_12 FBgn0052204 CG32204 http://flybase.net/reports/FBgn0052204.html protein_coding_gene CG32204 16-Dec-15 2015_12 DRSC09574 IE 2.613808098 4.792811906 2.330333898 1.473867504 -0.526476424 1.029875889 FBgn0263937 BG00008 http://flybase.net/reports/FBgn0263937.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0261579 CG42689 http://flybase.net/reports/FBgn0261579.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039638 dgt6 dim ë_-tubulin 6 http://flybase.net/reports/FBgn0039638.html protein_coding_gene "0007088=regulation of mitotic nuclear division, 0051297=centrosome organization, 0051225=spindle assembly, 0007052=mitotic spindle organization" "0005819=spindle, 0070652=HAUS complex, 0005875=microtubule associated complex" "mitotic spindle density 4, msd4, Dgt6, CG11881" "IPR028163=HAUS augmin-like complex subunit 6, N-terminal, IPR026797=HAUS augmin-like complex subunit 6" CG11881 16-Dec-15 2015_12 ENSMUSG00000038047(Haus6) viable FBgn0003958 upt upturned bristles http://flybase.net/reports/FBgn0003958.html gene 16-Dec-15 2015_12 "visible,recessive" "dorsocentral bristle,anterior scutellar bristle" FBgn0259785 pzg putzig http://flybase.net/reports/FBgn0259785.html "FBgn0083067, FBgn0037066" protein_coding_gene "0046872=metal ion binding, 0003682=chromatin binding, 0003677=DNA binding" "0045747=positive regulation of Notch signaling pathway, 0045931=positive regulation of mitotic cell cycle, 0051276=chromosome organization, 0022008=neurogenesis, 0006325=chromatin organization, 0046426=negative regulation of JAK-STAT cascade, 0035076=ecdysone receptor-mediated signaling pathway" "0005634=nucleus, 0005705=polytene chromosome interband, 0016589=NURF complex" "Pzg, p160, Pzg/Z4, Putzig, CG7752, Q9VP57_DROME, z4, Z4" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG7752 16-Dec-15 2015_12 ENSMUSG00000048410(Zfp407) DRSC11848 I -1.050601956 -2.025602304 -1.251805105 -1.494414055 0.619320857 0.60379245 FBgn0028172 l(3)S027302b lethal (3) S027302b http://flybase.net/reports/FBgn0028172.html gene "0273/02, l(3)S027302" 16-Dec-15 2015_12 "lethal,recessive" FBgn0261399 Pp1-Y1 "Protein phosphatase 1, Y-linked 1" http://flybase.net/reports/FBgn0261399.html "FBgn0046699, FBan0041534, FBgn0085674" protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation 0000164=protein phosphatase type 1 complex "Pp1Y1, CG41534, DmPp1-Y1, Pp1-Y1" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase" CG41534 16-Dec-15 2015_12 FBgn0261059 Sfp78E Seminal fluid protein 78E http://flybase.net/reports/FBgn0261059.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG42607 16-Dec-15 2015_12 FBgn0035751 CG14829 http://flybase.net/reports/FBgn0035751.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG14829 16-Dec-15 2015_12 FBgn0082350 HM388 HM388 http://flybase.net/reports/FBgn0082350.html gene 16-Dec-15 2015_12 FBgn0266214 CR44909 http://flybase.net/reports/FBgn0266214.html non_protein_coding_gene CR44909 16-Dec-15 2015_12 FBgn0267267 CR45703 http://flybase.net/reports/FBgn0267267.html non_protein_coding_gene CR45703 16-Dec-15 2015_12 FBgn0022082 l(2)k07525 lethal (2) k07525 http://flybase.net/reports/FBgn0022082.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0012051 CalpA Calpain-A http://flybase.net/reports/FBgn0012051.html FBgn0034444 protein_coding_gene "0005509=calcium ion binding, 0004198=calcium-dependent cysteine-type endopeptidase activity" "0021919=BMP signaling pathway involved in spinal cord dorsal/ventral patterning, 0050832=defense response to fungus, 0042335=cuticle development, 0030036=actin cytoskeleton organization, 0006508=proteolysis, 0009953=dorsal/ventral pattern formation, 0008340=determination of adult lifespan, 0016540=protein autoprocessing, 0006909=phagocytosis" "0015629=actin cytoskeleton, 0005737=cytoplasm, 0005622=intracellular, 0043025=neuronal cell body" "calpA, Calpain A, EST C, CG18152, Calpain lacking calmodulin-like domain, Calpain, calpain, CG7563, calpainA" "IPR011992=EF-hand domain pair, IPR022682=Peptidase C2, calpain, large subunit, domain III, IPR001300=Peptidase C2, calpain, catalytic domain, IPR022683=Peptidase C2, calpain, domain III, IPR002048=EF-hand domain, IPR000169=Cysteine peptidase, cysteine active site, IPR022684=Peptidase C2, calpain family, IPR018247=EF-Hand 1, calcium-binding site" CG7563 16-Dec-15 2015_12 "ENSDARG00000012341(capn9),ENSDARG00000045199(zgc:55262),ENSDARG00000055338(LOC565825),ENSDARG00000041864(capn3),ENSDARG00000052748(LOC565106),ENSDARG00000055592(capn2b),ENSDARG00000034211(capn2l),ENSDARG00000052702(capn1a),ENSDARG00000052720,ENSDARG00000004030,ENSDARG00000055715(LOC100332861),ENSDARG00000043035" "WBGene00000542(clp-1),WBGene00000547(clp-7)" "ENSXETG00000023310(CAPN9),ENSXETG00000023299(capn1),ENSXETG00000018607(capn8),ENSXETG00000018599(capn2)" "ENSMUSG00000031981(Capn9),ENSMUSG00000079110(Capn3),ENSMUSG00000024942(Capn1),ENSMUSG00000026509(Capn2),ENSMUSG00000038599(Capn8)" "ENSG00000135773(CAPN9),ENSG00000092529(CAPN3),ENSG00000014216(CAPN1),ENSG00000162909(CAPN2)" " adult stage , embryonic stage -- adult stage , oogenesis stage && larval stage , larval stage " " adult proventriculus

, ovary

, adult midgut | restricted

, adult central nervous system

, embryonic/larval hemocoel

" " embryonic stage | cycle 8-13 , adult stage , embryonic stage | early , larval stage " "

, adult midgut | restricted

, tritocerebrum | restricted

, protocerebrum | restricted

,

anterior , pole bud

, adult central nervous system | restricted

, embryonic/larval fat body

,

posterior " "viable,long lived,immune response defective" FBgn0016642 ER2-7A ER2-7A http://flybase.net/reports/FBgn0016642.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067317 Cby Chibby http://flybase.net/reports/FBgn0067317.html FBgn0038910 protein_coding_gene "0007367=segment polarity determination, 0030178=negative regulation of Wnt signaling pathway, 0007286=spermatid development, 0035082=axoneme assembly" "0030425=dendrite, 0005814=centriole, 0035869=ciliary transition zone, 0005739=mitochondrion" "cby, chibby, CG13415" IPR028118=Chibby family CG13415 16-Dec-15 2015_12 ENSDARG00000055918(cby1) ENSXETG00000006897() "viable,male semi-fertile,gravitaxis defective,auditory perception defective,small body" "denticle,ectopic,embryonic head,Johnston organ,chordotonal organ,scolopidial cilium,microtubule,cilium axoneme,ciliary basal body,ciliary transition zone,ciliary membrane,spermatid,Nebenkern derivative,embryonic/first instar larval cuticle,midgut constriction 1" FBgn0065520 l(2)SH1134 lethal (2) SH1134 http://flybase.net/reports/FBgn0065520.html gene l(2)SH2 1134 16-Dec-15 2015_12 "lethal,recessive" FBgn0264703 CR43972 http://flybase.net/reports/FBgn0264703.html pseudogene_attribute CR43972 16-Dec-15 2015_12 FBgn0039881 CG1971 http://flybase.net/reports/FBgn0039881.html protein_coding_gene CG1971 16-Dec-15 2015_12 viable DRSC28390 K 0.481974853 0.562227074 0.391371725 -0.034819512 1.989987787 -0.66991197 FBgn0033715 CG8490 http://flybase.net/reports/FBgn0033715.html protein_coding_gene CG8490 16-Dec-15 2015_12 viable FBgn0025333 anon-85Aa anon-85Aa http://flybase.net/reports/FBgn0025333.html gene 16-Dec-15 2015_12 FBgn0013141 sev::Dvir\sev sev::Dvir\sev http://flybase.net/reports/FBgn0013141.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0022712 406 406 http://flybase.net/reports/FBgn0022712.html gene 16-Dec-15 2015_12 FBgn0002714 mei-S282 meiotic from via Salaria 282 http://flybase.net/reports/FBgn0002714.html gene "0007143=female meiotic division, 0007067=mitotic nuclear division" mei-282 16-Dec-15 2015_12 "meiotic cell cycle defective,female,recessive,mitotic cell cycle defective" FBgn0038149 GILT1 Gamma-interferon-inducible lysosomal thiol reductase 1 http://flybase.net/reports/FBgn0038149.html protein_coding_gene 0015036=disulfide oxidoreductase activity "1900426=positive regulation of defense response to bacterium, 0055114=oxidation-reduction process" 0005886=plasma membrane "Gamma-interferon-inducible lysosomal thiol reductase, CG9796, GILT" IPR004911=Gamma interferon inducible lysosomal thiol reductase GILT CG9796 16-Dec-15 2015_12 ENSDARG00000056378(ifi30) "WBGene00015336(C02D5.2),WBGene00014052(ZK669.2)" ENSXETG00000025512(IFI30) ENSMUSG00000031838(Ifi30) ENSG00000216490(IFI30) "immune response defective,viable,fertile,body color defective" mesothoracic tergum DRSC16565 K -0.549458203 0.456991065 0.055643934 0.389739385 0.080759842 1.747843653 FBgn0082927 snoRNA:Me28S-G3255b snoRNA:Me28S-G3255b http://flybase.net/reports/FBgn0082927.html snoRNA_gene "DmSnR48b, CR34529, Me28S-Gm3255b" CR34529 16-Dec-15 2015_12 FBgn0260055 2L3301 http://flybase.net/reports/FBgn0260055.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0263325 CR43406 http://flybase.net/reports/FBgn0263325.html non_protein_coding_gene "mdcds_4123, mdcds_4120, CG43406" CR43406 16-Dec-15 2015_12 FBgn0028037 l(3)S100604 lethal (3) S100604 http://flybase.net/reports/FBgn0028037.html gene 1006/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0264989 CG44140 http://flybase.net/reports/FBgn0264989.html protein_coding_gene CG44140 16-Dec-15 2015_12 FBgn0000335 cmp crumpled http://flybase.net/reports/FBgn0000335.html gene cm 16-Dec-15 2015_12 "wing,dorsal row,ventral row,medial triple row,leg,macrochaeta,scutellar bristle,arista" FBgn0050085 Rif1 Rap1 interacting factor 1 http://flybase.net/reports/FBgn0050085.html FBgn0027510 protein_coding_gene "0006974=cellular response to DNA damage stimulus, 0035392=maintenance of chromatin silencing at telomere, 0030174=regulation of DNA-dependent DNA replication initiation" "0005634=nucleus, 0005694=chromosome, 0035012=polytene chromosome, telomeric region, 0005701=polytene chromosome chromocenter, 0005704=polytene chromosome band, 0005720=nuclear heterochromatin" "Rap1 interacting factor 1 homolog, CG30085, dRif1, BcDNA:LD22218" "IPR016024=Armadillo-type fold, IPR022031=Telomere-associated protein Rif1, N-terminal, IPR028566=Rif1" CG30085 16-Dec-15 2015_12 ENSDARG00000062650(rif1) viable FBgn0043366 EP2002b EP2002b http://flybase.net/reports/FBgn0043366.html gene 16-Dec-15 2015_12 visible tormogen cell FBgn0011200 l(1)304-71 lethal (1) 304-71 http://flybase.net/reports/FBgn0011200.html FBgn0010203 gene 304-71 16-Dec-15 2015_12 "lethal,recessive" FBgn0065845 l(2)SH0319 lethal (2) SH0319 http://flybase.net/reports/FBgn0065845.html gene l(2)SH2 0319 16-Dec-15 2015_12 "lethal,recessive" FBgn0003391 shg shotgun http://flybase.net/reports/FBgn0003391.html "FBgn0010661, FBgn0012050" protein_coding_gene "0005509=calcium ion binding, 0004872=receptor activity, 0042803=protein homodimerization activity, 0005515=protein binding, 0008013=beta-catenin binding, 0050839=cell adhesion molecule binding, 0017022=myosin binding" "0007399=nervous system development, 0030708=germarium-derived female germ-line cyst encapsulation, 0042078=germ-line stem cell division, 0007409=axonogenesis, 0008258=head involution, 0008356=asymmetric cell division, 0050832=defense response to fungus, 0007379=segment specification, 0007506=gonadal mesoderm development, 0035147=branch fusion, open tracheal system, 0007507=heart development, 0035262=gonad morphogenesis, 0044331=cell-cell adhesion mediated by cadherin, 0010004=gastrulation involving germ band extension, 0007155=cell adhesion, 0036099=female germ-line stem cell maintenance, 0042060=wound healing, 0030031=cell projection assembly, 0035019=somatic stem cell maintenance, 0035160=maintenance of epithelial integrity, open tracheal system, 0045186=zonula adherens assembly, 0002009=morphogenesis of an epithelium, 0007281=germ cell development, 0001748=optic lobe placode development, 0007411=axon guidance, 0035099=hemocyte migration, 0007424=open tracheal system development, 0001738=morphogenesis of a polarized epithelium, 0045176=apical protein localization, 0000902=cell morphogenesis, 0007420=brain development, 0007298=border follicle cell migration, 0048103=somatic stem cell division, 0007163=establishment or maintenance of cell polarity, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0008354=germ cell migration, 0016318=ommatidial rotation, 0007297=ovarian follicle cell migration, 0003151=outflow tract morphogenesis, 0035212=cell competition in a multicellular organism, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0001745=compound eye morphogenesis, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0008406=gonad development, 0071907=determination of digestive tract left/right asymmetry, 0007314=oocyte anterior/posterior axis specification, 0016337=single organismal cell-cell adhesion, 0007435=salivary gland morphogenesis, 0007280=pole cell migration, 0007370=ventral furrow formation, 0008105=asymmetric protein localization, 0048477=oogenesis, 0098730=male germline stem cell symmetric division" "0005887=integral component of plasma membrane, 0043296=apical junction complex, 0005915=zonula adherens, 0005886=plasma membrane, 0005938=cell cortex, 0016342=catenin complex, 0005914=spot adherens junction, 0005913=cell-cell adherens junction, 0016021=integral component of membrane, 0030175=filopodium, 0005912=adherens junction, 0055037=recycling endosome" "de-cad, com5, DE cadherin, cad, Shotgun/E-cadherin, D E-cad, Shg, DE Cadh, DE-CAD2, DE-Cad, E-Cadherin, E-cadherin, compaction defects 5, Cadherin-E, Drosophila epithelial cadherin, dE-Cadherin, DE-cadherin/Shotgun, E-Cad, Cadherin, l(2)10469, Drosophila E-cadherin, (DE)-cadherin, ECadh, de-cadherin, dEcad, ECad, DEcad, DCAD, Cad, DE Cadherin, DE[cyto], E-CAD, DE-cadh, ECadherin, DE-CADHERIN, DE-Cadherin, ECAD, D-cadherin, DE-CAD, l(2)k03401, DECadh, E-Ca, CT12481, DE-cadherin, De-cadherin, DE Cad, CADH, l(2)k10220, Drosophila melanogaster epithelial (DE)-cadherin, dE-cadherin, ECad2, cadh, De-Cad, DCad2, N-cad, cadherin, shg/DE-Cad, DEC, gp150, CadE, D-cad, D-Ecadherin, Ecadherin, eta-catenin, Cadh, DE, Shotgun, Ecad, DCad, DE-Cadh, CG3722, DCAD2, DECad, e-cad, DE-cad, DEcadherin, Drosophila E-Cadherin, epithelial cadherin, D-CAD2, DE-Cad2, DECAD, E-cad, e-cadherin" "IPR000742=EGF-like domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000233=Cadherin, cytoplasmic domain, IPR015919=Cadherin-like, IPR002126=Cadherin, IPR013032=EGF-like, conserved site, IPR027397=Catenin binding domain, IPR020894=Cadherin conserved site" CG3722 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage >=12 , embryonic stage | stage 17 , embryonic stage | stage 8 , egg stage | unfertilized egg " " amnioserosa

, midgut primordium

, gonadal sheath

, embryonic/larval tracheal system

, embryonic/larval dorsal vessel

, dorsal ectoderm

, epithelial cell

, embryonic/larval hindgut

, embryonic/larval salivary gland

, embryonic epidermis

, ventral neurogenic region

, unfertilized egg

, embryonic/larval foregut

, Malpighian tubule

, subperineurial glial cell

" " embryonic stage , embryonic stage | cellular blastoderm , embryonic stage | stage 17 , embryonic stage | stage 13-14 " " Malpighian tubule

, epidermis

, embryonic/larval hindgut

, gonad | restricted & anterior

, embryonic/larval salivary gland

, ectoderm

, embryonic/larval tracheal system

, gonad | restricted

" "cell polarity defective,immune response defective,dominant,lethal,viable,recessive,cell migration defective,cell non-autonomous,somatic clone,wound healing defective,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective,germline clone,cell adhesion defective,cell shape defective,increased cell death,visible,mitotic cell cycle defective,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "hemocyte,embryonic head,embryonic ventral epidermis,cell-cell adherens junction | embryonic stage, with shgR69,ventral furrow,border follicle cell,somatic clone,embryonic/first instar larval cuticle,oocyte,embryonic head & embryonic/first instar larval cuticle,ventral,egg chamber,epithelial cell,cardioblast,cardioblast & adherens junction,sensory mother cell,ommatidial precursor cluster,cell non-autonomous,organism | embryonic stage,ommatidium,wing,Malpighian tubule,tracheal branch primordium,embryonic/larval dorsal trunk,follicle stem cell,gonad,embryonic/larval hindgut,female germline stem cell,germline clone,cone cell,primary pigment cell,centripetally migrating follicle cell,male germline stem cell,embryonic/larval trachea,imaginal disc,cell-cell adherens junction | embryonic stage, with shgDEëÓ734-1316.Ubi.TAvicGFP-EGFP,germinal proliferation center hub,germline cell,maternal effect,embryonic epidermis,ovary,egg,embryonic/larval dorsal vessel,follicle cell,embryonic head epidermis,embryonic/first instar larval cuticle & embryonic head,presumptive embryonic/larval tracheal system,endoderm,neurogenic region,presumptive embryonic/larval peripheral nervous system,stomatogastric nervous system,visual primordium,gonadal sheath proper primordium,fat body/gonad primordium,male,cell | cell autonomous | somatic clone,embryonic/larval tracheal system,embryonic epidermis & embryonic head,head,lateral,tracheal system,embryonic optic lobe primordium,embryonic optic lobe,tracheolar cell,embryonic trachea & cortical actin cytoskeleton,Bolwig organ,posterior spiracle primordium,presumptive embryonic/larval nervous system,adherens junction | embryonic stage,embryonic/larval dorsal branch,border follicle cell & filopodium | somatic clone | cell non-autonomous,border follicle cell & filopodium | somatic clone,cell | apical | cell autonomous | somatic clone,nurse cell,nurse cell ring canal,wing disc,apical plasma membrane & cell & dorsal mesothoracic disc & third instar larva | somatic clone,cyst progenitor cell,microtubule & adherens junctionbtl.PS,morphogenetic furrow,nucleus | blastoderm stagemat.ë±Tub67C.THsimVP16,plasma membrane | blastoderm stagemat.ë±Tub67C.THsimVP16,spindlemat.ë±Tub67C.THsimVP16,neuroblast,gastrula embryo,zonula adherens | embryonic stagemat.ë±Tub67C.THsimVP16,embryonic/larval brain,anterior protocerebral neuromere,neuropil associated CNS glial cell,cortex associated CNS glial cell,neuropil,ectopic,fascicle,lamina cortex & satellite glial cellnrv2.PS,embryonic/larval cell body glial cell,wing margin,denticle & embryonic epidermis | somatic cloneë±Tub84B.PP,denticle,posterior compartment,embryonic/larval salivary gland,histoblast,histoblast nest,male genitalia,heat sensitive,wing hair,wing blade,flight muscle" DRSC27751 K 0.330875855 0.250418305 0.002929325 0.044303028 1.557147448 -0.831267202 FBgn0003060 CG9757 http://flybase.net/reports/FBgn0003060.html protein_coding_gene "anon-Pen50DE, GCR 20, GCR-20, pen50DE, GCR20, Pen50DE" CG9757 16-Dec-15 2015_12 FBgn0250741 l(3)S044324 lethal (3) S044324 http://flybase.net/reports/FBgn0250741.html gene l(3)s044324 16-Dec-15 2015_12 lethal FBgn0052313 CG32313 http://flybase.net/reports/FBgn0052313.html protein_coding_gene 0005576=extracellular region "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG32313 16-Dec-15 2015_12 viable FBgn0001201 Hiv Haploinviable http://flybase.net/reports/FBgn0001201.html gene "Dominant Lethal in 7C, unnamed, L(1)7C" 16-Dec-15 2015_12 FBgn0031610 CG15436 http://flybase.net/reports/FBgn0031610.html protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG15436 16-Dec-15 2015_12 WBGene00009448(zfp-2) "viable,fertile" DRSC29550 K 0.87064539 0.118036584 0.37362367 -0.15678215 -0.508593914 -3.87609668 FBgn0028919 CG16865 http://flybase.net/reports/FBgn0028919.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" 0071013=catalytic step 2 spliceosome BG:DS00941.3 IPR029704=UPF0428 family CG16865 16-Dec-15 2015_12 ENSDARG00000067981(zgc:103697) WBGene00013434(Y66D12A.8) ENSXETG00000020806(TNeu084h20.1) ENSMUSG00000006423(C330007P06Rik) ENSG00000018610(CXorf56) "viable,fertile" FBgn0045038 Proc Proctolin http://flybase.net/reports/FBgn0045038.html FBgn0031958 protein_coding_gene "0005184=neuropeptide hormone activity, 0071860=proctolin receptor binding" "0010460=positive regulation of heart rate, 0007218=neuropeptide signaling pathway" 0005615=extracellular space "proct, CG7105, PROCT, Prct, Proct, proctolin, Proc, PROC" CG7105 16-Dec-15 2015_12 "viable,fertile" embryonic/larval heart FBgn0032492 Prosë±6T "Proteasome ë±6 subunit, Testis-specific" http://flybase.net/reports/FBgn0032492.html protein_coding_gene 0004298=threonine-type endopeptidase activity "0006511=ubiquitin-dependent protein catabolic process, 0007291=sperm individualization, 0045824=negative regulation of innate immune response, 0006974=cellular response to DNA damage stimulus, 0050829=defense response to Gram-negative bacterium, 0007290=spermatid nucleus elongation" "0019773=proteasome core complex, alpha-subunit complex, 0001673=male germ cell nucleus, 0005829=cytosol, 0005737=cytoplasm, 0005634=nucleus" "Proteasome alpha6T subunit, Alpha6T, alpha6T, Prosalpha6T, prosalpha6T, 5648, CG5648" "IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR023332=Proteasome A-type subunit, IPR001353=Proteasome, subunit alpha/beta" CG5648 16-Dec-15 2015_12 ENSDARG00000026900 YMR314W(PRE5) WBGene00003927(pas-6) ENSXETG00000019680(PSMA1) ENSMUSG00000030751(Psma1) ENSG00000129084(PSMA1) "viable,male sterile,recessive" "cystic bulge,spermatozoon,nucleus & elongation stage spermatid" FBgn0264085 CR43754 http://flybase.net/reports/FBgn0264085.html non_protein_coding_gene lincRNA.14 CR43754 16-Dec-15 2015_12 FBgn0039163 CG5515 http://flybase.net/reports/FBgn0039163.html protein_coding_gene "IPR006575=RWD domain, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG5515 16-Dec-15 2015_12 ENSDARG00000015930(rwdd1) YDR152W(GIR2) WBGene00012037(T26E3.4) ENSXETG00000014077(rwdd1) ENSMUSG00000019782(Rwdd1) ENSG00000111832(RWDD1) viable FBgn0265307 CR44280 http://flybase.net/reports/FBgn0265307.html non_protein_coding_gene lincRNA.266 CR44280 16-Dec-15 2015_12 FBgn0005415 l(1)adl4 lethal (1) adl4 http://flybase.net/reports/FBgn0005415.html gene l(1)adl-4 16-Dec-15 2015_12 "lethal,heat sensitive,short lived,partially lethal - majority die" FBgn0003889 ë_Tub85D ë_-Tubulin at 85D http://flybase.net/reports/FBgn0003889.html protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005525=GTP binding, 0003924=GTPase activity" "0007435=salivary gland morphogenesis, 0007017=microtubule-based process, 0051258=protein polymerization" "0005874=microtubule, 0045298=tubulin complex" "beta2 tubulin, beta2-tubulin, Tub, beta-tub85D, beta-tubulin85D, DTB4, beta2tubulin, beta-tubulin, beta2-Tubulin, ms(3)KK[D], beta tubulin, b2 tubulin, betaTub85D, beta-Tubulin 85D, beta2t, betatub85D, tubulin, 2t, beta[[2]]-tubulin, Beta tubulin, beta2, beta-Tub85D, beta(2)Tubulin, BETA2, beta2-tub, D.m.BETA-85D, testis-specific beta-tubulin, Dmbeta2, betaTub2, beta 2 tubulin, BETA 85D, beta;Tub85D, beta(2)Tu, beta85D, CG9359, beta(2)Tub, beta-Tubulin, beta-Tubulin at 85D, beta2tub, beta-tub, B2t, betaTubulin85D" "IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR000217=Tubulin, IPR002453=Beta tubulin, IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR013838=Beta tubulin, autoregulation binding site" CG9359 16-Dec-15 2015_12 "ENSDARG00000041723(zgc:55461),ENSDARG00000002344(tubb2c),ENSDARG00000035423(zgc:123194),ENSDARG00000038198(zgc:153426),ENSDARG00000037997(tubb5),ENSDARG00000016301(zgc:65894)" YFL037W(TUB2) WBGene00006538(tbb-4) "ENSXETG00000023473(tubb3),ENSXETG00000018032(BC064166.1),ENSXETG00000021860(tubb2),ENSXETG00000024084(tubb5)" "ENSMUSG00000045136(Tubb2b),ENSMUSG00000036752(Tubb2c),ENSMUSG00000058672(Tubb2a),ENSMUSG00000062591(Tubb4),ENSMUSG00000001525(Tubb5)" "ENSG00000137285(TUBB2B),ENSG00000188229(TUBB2C),ENSG00000137267(TUBB2A),ENSG00000104833(TUBB4),ENSG00000183311,ENSG00000137379,ENSG00000196230(TUBB)" " spermatogenesis && adult stage , embryonic stage , pupal stage , embryonic stage | 0-3 hr , prepupal stage , larval stage | third instar " " testis

, somatic mesoderm

{ e neur* } , somatic mesoderm

{ e E(spl)* } , somatic mesoderm

{ e amx* } , larval muscle system

{ e Dl* } , somatic mesoderm

{ e mam* } , somatic mesoderm

, somatic mesoderm

{ e Nj* } , somatic mesoderm

{ e bib* } " larval stage | third instar dorsal mesothoracic disc

"male sterile,recessive,cytokinesis defective,male fertile,meiotic cell cycle defective,wild-type,male,semidominant,electrophoretic variant,dominant,female fertile,viable" "spermatid,primary spermatocyte cyst,axoneme,spermatozoon,spermatid axoneme,microtubule,testis,microtubule & testis,spermatid & nucleus,presumptive embryonic salivary gland,meiotic cell cycle & spindle | male,meiotic cell cycle | male,spermatocyte,fusion competent cell,muscle founder cell,Nebenkern derivative,meiosis II,meiosis I,spindle & meiotic cell cycle | male,spindle,astral microtubule | male,spindle microtubule | male,spermatozoon & axoneme,seminal vesicle" DRSC16910 IE 3.47296445 -0.301228752 2.577472917 -0.737393981 -0.540914464 -0.050679354 FBgn0085369 CG34340 http://flybase.net/reports/FBgn0085369.html "FBgn0031557, FBgn0031556" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated, 0007517=muscle organ development" 0005634=nucleus "CG2808, CG10017" "IPR017970=Homeobox, conserved site, IPR003654=OAR domain, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG34340 16-Dec-15 2015_12 ENSDARG00000069329(drgx) ENSXETG00000021154(RAX) ENSMUSG00000021685(Otp) viable FBgn0069151 mcl(3)Z3370 mcl(3)Z3370 http://flybase.net/reports/FBgn0069151.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0052081 CG32081 http://flybase.net/reports/FBgn0052081.html "FBgn0036114, FBgn0064996" protein_coding_gene 0015171=amino acid transmembrane transporter activity 0006810=transport "FBgn 52081, CG11806, BcDNA:AT27573" "IPR013057=Amino acid transporter, transmembrane domain" CG32081 16-Dec-15 2015_12 "YNL101W(AVT4),YKL146W(AVT3)" "viable,fertile" DRSC09861 K 0.191345641 0.484433443 -0.163845201 0.553202622 1.785168679 0.603234702 FBgn0267192 CR45632 http://flybase.net/reports/FBgn0267192.html non_protein_coding_gene lincRNA.829 CR45632 16-Dec-15 2015_12 FBgn0036259 CG9760 http://flybase.net/reports/FBgn0036259.html protein_coding_gene CG9760 16-Dec-15 2015_12 "viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0041730 ovr overheated http://flybase.net/reports/FBgn0041730.html gene 0008344=adult locomotory behavior 16-Dec-15 2015_12 "locomotor behavior defective,heat sensitive" FBgn0267729 CR46060 http://flybase.net/reports/FBgn0267729.html non_protein_coding_gene CR46060 16-Dec-15 2015_12 FBgn0085698 CG41569 http://flybase.net/reports/FBgn0085698.html FBan0041569 protein_coding_gene 16-Dec-15 2015_12 FBgn0262302 mir-954 mir-954 stem loop http://flybase.net/reports/FBgn0262302.html miRNA_gene "miR-954, CR43009, dme-mir-954, dme-miR-954-5p" CR43009 16-Dec-15 2015_12 viable FBgn0000441 dfw deflected wing http://flybase.net/reports/FBgn0000441.html gene 16-Dec-15 2015_12 "visible,female sterile,viable,male,female,poor,male fertile,sterile,partially lethal - majority live" "wing,eye" FBgn0260507 Pak::Pkc53E http://flybase.net/reports/FBgn0260507.html engineered_fusion_gene Pak-53E 16-Dec-15 2015_12 FBgn0053269 CG33269 http://flybase.net/reports/FBgn0053269.html "FBgn0036175, FBgn0040819, FBgn0052084" protein_coding_gene "CG32084, CG14139, CG6100" CG33269 16-Dec-15 2015_12 FBgn0004829 fir fireworks http://flybase.net/reports/FBgn0004829.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,mitotic cell cycle defective" "neuroblast,mitotic metaphase,meiosis II,spermatid,Nebenkern derivative" FBgn0058335 CG40335 http://flybase.net/reports/FBgn0058335.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005256 l(3)SG75 lethal (3) SG75 http://flybase.net/reports/FBgn0005256.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061079 l(3)S014708 lethal (3) S014708 http://flybase.net/reports/FBgn0061079.html gene 0147/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0061093 l(3)S011001a lethal (3) S011001a http://flybase.net/reports/FBgn0061093.html gene 16-Dec-15 2015_12 lethal FBgn0031389 CG4259 http://flybase.net/reports/FBgn0031389.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH173 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG4259 16-Dec-15 2015_12 viable FBgn0034191 CG6984 http://flybase.net/reports/FBgn0034191.html protein_coding_gene 0004300=enoyl-CoA hydratase activity 0008152=metabolic process "IPR018376=Enoyl-CoA hydratase/isomerase, conserved site, IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily" CG6984 16-Dec-15 2015_12 ENSDARG00000063692(zgc:158321) WBGene00001151(ech-2) ENSMUSG00000039063(Echdc3) ENSG00000134463(ECHDC3) viable DRSC07013 I 6.422902345 -0.830144718 -0.335946628 0.692738551 -0.271182461 -0.297267751 FBgn0265413 CG44325 http://flybase.net/reports/FBgn0265413.html "FBgn0030080, FBgn0030079" protein_coding_gene "CG15366, CG7267" CG44325 16-Dec-15 2015_12 FBgn0041786 S(Sev-CycE)D16 S(Sev-CycE)D16 http://flybase.net/reports/FBgn0041786.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011880 tRNA:I:42A transfer RNA:ile:42A http://flybase.net/reports/FBgn0011880.html "FBgn0050313, FBgn0060202" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033433=AUU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna7-IleAAT, AE002769.trna15-IleAAT, tRNA[Ile], CR30313, tRNA:ile:42A, tRNA:I:AAT:AE002769, tRNA Ile" CR30313 16-Dec-15 2015_12 FBgn0020813 l(4)Fox lethal (4) Fox http://flybase.net/reports/FBgn0020813.html gene 16-Dec-15 2015_12 FBgn0264947 CR44116 http://flybase.net/reports/FBgn0264947.html non_protein_coding_gene CR44116 16-Dec-15 2015_12 FBgn0266570 CG2982 http://flybase.net/reports/FBgn0266570.html "FBgn0029704, FBgn0022753" protein_coding_gene "0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, 0005506=iron ion binding, 0032453=histone demethylase activity (H3-K4 specific), 0051864=histone demethylase activity (H3-K36 specific)" "0070544=histone H3-K36 demethylation, 0045892=negative regulation of transcription, DNA-templated, 0034720=histone H3-K4 demethylation" 0005634=nucleus "unnamed, anon-4Bd" "IPR013109=Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, IPR003347=JmjC domain" CG2982 16-Dec-15 2015_12 ENSDARG00000067838(zgc:162967) WBGene00020902(jmjc-1) ENSXETG00000002045(MINA) ENSMUSG00000046791(2410016O06Rik) FBgn0030270 CG15199 http://flybase.net/reports/FBgn0030270.html protein_coding_gene 0005615=extracellular space DIGF-3 IPR029277=Single domain Von Willebrand factor type C domain CG15199 16-Dec-15 2015_12 viable FBgn0002768 mit(1)20 mitotic 20 http://flybase.net/reports/FBgn0002768.html gene 16-Dec-15 2015_12 FBgn0069955 CG41065 http://flybase.net/reports/FBgn0069955.html protein_coding_gene 16-Dec-15 2015_12 FBgn0015986 l(2)PC4-P lethal (2) PC4-P http://flybase.net/reports/FBgn0015986.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267026 CR45470 http://flybase.net/reports/FBgn0267026.html pseudogene_attribute CR45470 16-Dec-15 2015_12 FBgn0005151 l(2)G84 lethal (2) G84 http://flybase.net/reports/FBgn0005151.html gene 16-Dec-15 2015_12 lethal FBgn0023400 C55 C55 http://flybase.net/reports/FBgn0023400.html gene 16-Dec-15 2015_12 FBgn0004041 yea7 yeast 7 http://flybase.net/reports/FBgn0004041.html gene 16-Dec-15 2015_12 FBgn0045474 Gr77a Gustatory receptor 77a http://flybase.net/reports/FBgn0045474.html "FBgn0041230, FBgn0052433" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "GR77E.1, 77E.1, CG32433, Gr77E1, Gustatory receptor 77E.1, GR77a" IPR013604=7TM chemoreceptor CG32433 16-Dec-15 2015_12 FBgn0264844 CR44052 http://flybase.net/reports/FBgn0264844.html non_protein_coding_gene CR44052 16-Dec-15 2015_12 FBgn0004544 l(4)102CDo lethal (4) 102CDo http://flybase.net/reports/FBgn0004544.html gene "l(4)CDo, l(4)30" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0001551 l(1)18Fa lethal (1) 18Fa http://flybase.net/reports/FBgn0001551.html gene l(1)HC233 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031514 CG3332 http://flybase.net/reports/FBgn0031514.html protein_coding_gene IPR004878=Otopetrin CG3332 16-Dec-15 2015_12 ENSDARG00000021566 "WBGene00018478(otpl-5),WBGene00017034(otpl-2),WBGene00018479(otpl-6),WBGene00018480(otpl-7),WBGene00010403(otpl-8)" "ENSXETG00000006849(),ENSXETG00000016028(OTOP1),ENSXETG00000027433(),ENSXETG00000012496(),ENSXETG00000006252(),ENSXETG00000027068()" "ENSMUSG00000050201(Otop2),ENSMUSG00000018862(Otop3),ENSMUSG00000051596(Otop1)" "ENSG00000183034(OTOP2),ENSG00000182938(OTOP3)" "visible,viable" "wing,mesothoracic tergum" DRSC00594 I -0.016380007 -2.205016852 -0.532506015 -0.016646432 1.086811359 0.775698678 FBgn0037739 CG12948 http://flybase.net/reports/FBgn0037739.html protein_coding_gene IPR028019=Protein of unknown function DUF4508 CG12948 16-Dec-15 2015_12 viable FBgn0016014 l(3)64Am lethal (3) 64Am http://flybase.net/reports/FBgn0016014.html gene l(3)SH13 16-Dec-15 2015_12 "lethal,recessive" FBgn0066332 prem premjera http://flybase.net/reports/FBgn0066332.html gene "0007611=learning or memory, 0008355=olfactory learning, 0048149=behavioral response to ethanol" 16-Dec-15 2015_12 "memory defective,chemical sensitive" FBgn0003911 Tyr2 Tyrosine 2 http://flybase.net/reports/FBgn0003911.html gene "Tyrosinase, tyrosinase, Tyr-2, Tyrosinase-2" 16-Dec-15 2015_12 FBgn0265920 CR44709 http://flybase.net/reports/FBgn0265920.html non_protein_coding_gene "lincRNA.433, lincRNA.434" CR44709 16-Dec-15 2015_12 FBgn0000867 fs(1)M62 female sterile (1) M62 http://flybase.net/reports/FBgn0000867.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0267422 CR45775 http://flybase.net/reports/FBgn0267422.html pseudogene_attribute CR45775 16-Dec-15 2015_12 FBgn0011871 tRNA:G3:57BCa transfer RNA:gly3:57BCa http://flybase.net/reports/FBgn0011871.html "FBgn0003783, FBgn0050207, FBgn0060227" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033462=GGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna57-GlyGCC, tRNA[Gly-GCC], tRNA:gly3:57BCa, AE002575.trna13-GlyGCC, tRNA:G:GCC:AE002575-b, CR30207" CR30207 16-Dec-15 2015_12 FBgn0004999 crip cripple http://flybase.net/reports/FBgn0004999.html gene 16-Dec-15 2015_12 visible leg FBgn0020906 Jon25Bi Jonah 25Bi http://flybase.net/reports/FBgn0020906.html "FBgn0001284, FBtr0079054, FBpp0078690" protein_coding_gene "0004175=endopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "Jon25B, CG8867, Serine protease 4, Jon25, 25B, SP137, Jonah 25B, Ser4" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG8867 16-Dec-15 2015_12 "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" larval stage | third instar embryonic/larval digestive system | restricted

"viable,visible" trichogen cell FBgn0085638 CG41378 http://flybase.net/reports/FBgn0085638.html FBan0041378 protein_coding_gene IPR004911=Gamma interferon inducible lysosomal thiol reductase GILT CG41378 16-Dec-15 2015_12 FBgn0020570 anon-85Cb anon-85Cb http://flybase.net/reports/FBgn0020570.html gene unnamed 16-Dec-15 2015_12 FBgn0011126 l(1)Q89 lethal (1) Q89 http://flybase.net/reports/FBgn0011126.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0037138 P5CDh1 delta-1-Pyrroline-5-carboxylate dehydrogenase 1 http://flybase.net/reports/FBgn0037138.html protein_coding_gene "0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, 0003842=1-pyrroline-5-carboxylate dehydrogenase activity" "0006537=glutamate biosynthetic process, 0007005=mitochondrion organization, 0006560=proline metabolic process, 0055114=oxidation-reduction process, 0006561=proline biosynthetic process" "0005759=mitochondrial matrix, 0005739=mitochondrion" "delta-1-pyrroline-5-carboxylate dehydrogenase, P5CDh, CG7145, DmP5CDh1" "IPR016163=Aldehyde dehydrogenase, C-terminal, IPR029510=Aldehyde dehydrogenase, glutamic acid active site, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR015590=Aldehyde dehydrogenase domain, IPR005931=Delta-1-pyrroline-5-carboxylate dehydrogenase, IPR016161=Aldehyde/histidinol dehydrogenase, IPR016160=Aldehyde dehydrogenase, cysteine active site" CG7145 16-Dec-15 2015_12 ENSDARG00000038207(aldh4a1) YHR037W(PUT2) WBGene00000112(alh-6) ENSXETG00000018531(ALDH4A1) ENSMUSG00000028737(Aldh4a1) ENSG00000159423(ALDH4A1) "lethal,recessive,developmental rate defective,body size defective,viable" mitochondrion FBgn0041240 Gr57a Gustatory receptor 57a http://flybase.net/reports/FBgn0041240.html FBgn0034544 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 57B.1, GR57a, Gr57B1, 57B.1, GR57B.1, CG13441" IPR013604=7TM chemoreceptor CG13441 16-Dec-15 2015_12 viable FBgn0262394 mir-281-1 mir-281-1 stem loop http://flybase.net/reports/FBgn0262394.html "FBgn0069126, FBgn0082177, FBgn0086606, FBgn0067712, FBgn0067711, FBgn0262224" miRNA_gene "mir-281-1, miR-281a, dme-miR-281, CR33592, CR33595, CR42931, mir-281-1*, CR33594, miR-281-1, dme-mir-281-1, mir-281aS, mir-281, dme-miR-281-1, miR-281aS, mir-281a, miR-281" CR42931 16-Dec-15 2015_12 viable FBgn0019703 l(2)50CDa lethal (2) 50CDa http://flybase.net/reports/FBgn0019703.html gene 16-Dec-15 2015_12 FBgn0023061 l(1)2Dl lethal (1) 2Dl http://flybase.net/reports/FBgn0023061.html gene "C2/5.11, B2/34.27, E3/36.11" 16-Dec-15 2015_12 "lethal,recessive" FBgn0050227 tRNA:CR30227 transfer RNA:CR30227 http://flybase.net/reports/FBgn0050227.html FBgn0060011 tRNA_gene 0033416=UGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002787.trna48-TrpCCA, chr2R.trna31-TrpCCA, CR30227, tRNA:W:CCA:AE002787-b" CR30227 16-Dec-15 2015_12 FBgn0024270 ZAM\pol pol http://flybase.net/reports/FBgn0024270.html transposable_element_gene "0003676=nucleic acid binding, 0008907=integrase activity" 0015074=DNA integration "ZAM integrase, ZAM-IN, pol, ORF2, ZAM RTase" "IPR021109=Aspartic peptidase domain, IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0266618 CR45125 http://flybase.net/reports/FBgn0266618.html non_protein_coding_gene CR45125 16-Dec-15 2015_12 FBgn0069125 mir-P323-1 mir-P323-1 http://flybase.net/reports/FBgn0069125.html miRNA_gene 16-Dec-15 2015_12 FBgn0040729 CG15126 http://flybase.net/reports/FBgn0040729.html protein_coding_gene CG15126 16-Dec-15 2015_12 viable FBgn0003741 tra transformer http://flybase.net/reports/FBgn0003741.html protein_coding_gene "0005515=protein binding, 0036002=pre-mRNA binding" "0046660=female sex differentiation, 0019101=female somatic sex determination, 0017148=negative regulation of translation, 0018993=somatic sex determination, 0007530=sex determination, 0007548=sex differentiation, 0030237=female sex determination, 0008380=RNA splicing, 0000245=spliceosomal complex assembly, 0045433=male courtship behavior, veined wing generated song production, 0007541=sex determination, primary response to X:A ratio, 0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0005634=nucleus" "Dmtra, CG16724, Transformer, TRA, Tra" IPR010519=Fruit fly transformer CG16724 16-Dec-15 2015_12 " embryonic stage -- adult stage , larval stage--adult stage | female , pupal stage--adult stage " organism

"female sterile,male fertile,viable,fertile,visible,male limited,wild-type,sex-determination defective,dominant,neuroanatomy defective,male,courtship behavior defective,sterile,recessive,female,locomotor behavior defective,mating defective,behavior defective,reduced,male sterile,partially,song defective,mating behavior defective" "germline cell,adult external abdomen,male reproductive system,spermatocyte fusome,spermatocyte ring canal,ovary,male genitalia,sex comb,gonad,adult brain & neuron | medial | female,gonadal sheath proper primordium,female,spectrosome,fusome,nurse cell ring canal,serotonergic neuron,adult fruitless pMP-e (female) neuron,ectopic,hub cell,adult brain,female genitalia,male,prothoracic leg taste bristle,adult nervous system,male genital disc,female genital disc,female repressed primordium,antennal lobe glomerulus DA1,abdomen,seminal receptacle,spermathecum,testis,spermatozoon,germline cell | embryonic stage,flight muscle,male limited" FBgn0052985 CG32985 http://flybase.net/reports/FBgn0052985.html FBgn0032081 protein_coding_gene 0003824=catalytic activity "0032504=multicellular organism reproduction, 0008152=metabolic process" "gi22945998, CG17789, gi21430910" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG32985 16-Dec-15 2015_12 viable FBgn0010091 Su(vg)B27 Suppressor of vestigial B27 http://flybase.net/reports/FBgn0010091.html gene "vg[BUR27], vg[[BUR27]]" 16-Dec-15 2015_12 FBgn0083044 snoRNA:ë¬18S-1397 snoRNA:ë¬18S-1397 http://flybase.net/reports/FBgn0083044.html snoRNA_gene "chr3L:5736789..5736893, CR34637, psi18S-1397, Psi 18S-1397, Psi18S-1397" CR34637 16-Dec-15 2015_12 FBgn0266761 shg::Mmus\cdh1 http://flybase.net/reports/FBgn0266761.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0000783 fs(1)A1559 female sterile (1) A1559 http://flybase.net/reports/FBgn0000783.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0000653 ff fluff http://flybase.net/reports/FBgn0000653.html gene 16-Dec-15 2015_12 "visible,viable,fertile" "macrochaeta,wing" FBgn0031829 Osm6 Osm-6 ortholog (C. elegans) http://flybase.net/reports/FBgn0031829.html protein_coding_gene "0042384=cilium assembly, 0007018=microtubule-based movement, 0060271=cilium morphogenesis" "0030990=intraciliary transport particle, 0005871=kinesin complex, 0030992=intraciliary transport particle B, 0005929=cilium" "CG9595, NGD5, Osm-6, osm-6, IFT52, OSM-6" CG9595 16-Dec-15 2015_12 ENSDARG00000045025(ift52) WBGene00003886(osm-6) ENSXETG00000012124(TEgg016a04.1) ENSMUSG00000017858(Ift52) ENSG00000101052(IFT52) viable FBgn0266936 CR45387 http://flybase.net/reports/FBgn0266936.html non_protein_coding_gene CR45387 16-Dec-15 2015_12 FBgn0267284 CR45720 http://flybase.net/reports/FBgn0267284.html non_protein_coding_gene lincRNA.32 CR45720 16-Dec-15 2015_12 FBgn0003954 unexpanded-irregular unexpanded irregular http://flybase.net/reports/FBgn0003954.html gene unr 16-Dec-15 2015_12 "visible,fertile,reduced" wing FBgn0261110 G38 http://flybase.net/reports/FBgn0261110.html gene 16-Dec-15 2015_12 male fertile FBgn0261109 mrn marionette http://flybase.net/reports/FBgn0261109.html "FBgn0036513, FBgn0061793, FBgn0002840" protein_coding_gene "0004003=ATP-dependent DNA helicase activity, 0000990=core RNA polymerase binding transcription factor activity, 0001671=ATPase activator activity" "0001111=promoter clearance from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0010224=response to UV-B, 0006366=transcription from RNA polymerase II promoter, 0001113=transcriptional open complex formation at RNA polymerase II promoter, 0006289=nucleotide-excision repair" "0000439=core TFIIH complex, 0005675=holo TFIIH complex, 0005634=nucleus" "ms(3)nc16, CG7764, Tfb2, 154538_at, TFB2, Dmp52, p52, l(3)E35, marionnette, anon-WO0118547.648, nc16" IPR004598=Transcription factor TFIIH subunit p52/Tfb2 CG7764 16-Dec-15 2015_12 ENSDARG00000036071(gtf2h4) YPL122C(TFB2) WBGene00013529(Y73F8A.24) "ENSXETG00000007263(Tfb2),ENSXETG00000010654()" ENSMUSG00000001524(Gtf2h4) "ENSG00000215476,ENSG00000213780(GTF2H4),ENSG00000221974" FBgn0034031 CG12963 http://flybase.net/reports/FBgn0034031.html FBgn0063704 protein_coding_gene BcDNA:AT28470 CG12963 16-Dec-15 2015_12 viable FBgn0036818 CG14074 http://flybase.net/reports/FBgn0036818.html protein_coding_gene CG14074 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263585 CR43610 http://flybase.net/reports/FBgn0263585.html non_protein_coding_gene lincRNA.59 CR43610 16-Dec-15 2015_12 FBgn0259216 RhoGAP102A Rho GTPase activating protein at 102A http://flybase.net/reports/FBgn0259216.html "FBgn0039898, FBgn0054013, FBgn0082856" protein_coding_gene 0005096=GTPase activator activity 0043547=positive regulation of GTPase activity "BP1050, CG34013, CG42316, CG1748, mlncRNA102B1, Dm_4:1183, RhoGAP102A, unnamed, rhoGAP102A" "IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG42316 16-Dec-15 2015_12 YPL115C(BEM3) "ENSMUSG00000039831(Arhgap29),ENSMUSG00000035697(Hmha1),ENSMUSG00000036246(Gmip)" FBgn0052481 tRNA:CR32481 transfer RNA:CR32481 http://flybase.net/reports/FBgn0052481.html FBgn0060192 tRNA_gene 0033435=AUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:I:TAT:AE002584-b, AE002584.trna2-IleTAT, chr3L.trna2-IleTAT, CR32481" CR32481 16-Dec-15 2015_12 FBgn0038821 CG17267 http://flybase.net/reports/FBgn0038821.html protein_coding_gene CG17267 16-Dec-15 2015_12 FBgn0065145 l(3)SH091 lethal (3) SH091 http://flybase.net/reports/FBgn0065145.html gene l(2)SH3 091 16-Dec-15 2015_12 "lethal,recessive" FBgn0051086 CG31086 http://flybase.net/reports/FBgn0051086.html FBgn0039416 protein_coding_gene CG14558 "IPR024518=Domain of unknown function DUF3421, IPR006616=DM9 repeat" CG31086 16-Dec-15 2015_12 viable FBgn0028567 robl62A robl62A http://flybase.net/reports/FBgn0028567.html FBgn0035222 protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex "CG1014, rob162A" "IPR004942=Roadblock/LAMTOR2 domain, IPR016561=Dynein light chain roadblock-type 1/2" CG1014 16-Dec-15 2015_12 FBgn0060730 l(3)S067309 lethal (3) S067309 http://flybase.net/reports/FBgn0060730.html gene 0673/09 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0052343 Atac3 Ada2a-containing complex component 3 http://flybase.net/reports/FBgn0052343.html FBgn0035130 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0004402=histone acetyltransferase activity" "0006355=regulation of transcription, DNA-templated, 0016573=histone acetylation, 0006338=chromatin remodeling" "0005634=nucleus, 0005671=Ada2/Gcn5/Ada3 transcription activator complex" "ATAC complex component 3, CG6994, cg6994, dATAC3, CG32343" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG32343 16-Dec-15 2015_12 "ENSDARG00000054344(gabpb2b),ENSDARG00000007943(gabpb2a),ENSDARG00000023659(zgc:154083)" ENSG00000167612(ANKRD33) "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0030330 Tango10 Transport and Golgi organization 10 http://flybase.net/reports/FBgn0030330.html protein_coding_gene "0048813=dendrite morphogenesis, 0009306=protein secretion, 0007517=muscle organ development" 0005829=cytosol "TANGO10, Transport and Golgi organization, CG1841, tango10" "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR011705=BTB/Kelch-associated" CG1841 16-Dec-15 2015_12 ENSMUSG00000000202(Btbd17) ENSG00000204347(BTBD17) DRSC19807 IE -0.172547307 3.120933771 -1.077524622 -1.735624488 -0.033408575 -0.265975694 FBgn0040054 CG12475 http://flybase.net/reports/FBgn0040054.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265513 E(comt6)21E http://flybase.net/reports/FBgn0265513.html gene Enhancer of comatose[6] 21E 16-Dec-15 2015_12 FBgn0010662 l(2)10481 lethal (2) 10481 http://flybase.net/reports/FBgn0010662.html FBgn0010533 gene l(2)03263 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0004427 LysD Lysozyme D http://flybase.net/reports/FBgn0004427.html FBgn0002575 protein_coding_gene "0003796=lysozyme activity, 0004568=chitinase activity" 0019730=antimicrobial humoral response "lysozyme, CG9118, lysD" "IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR023346=Lysozyme-like domain, IPR001916=Glycoside hydrolase, family 22, IPR019799=Glycoside hydrolase, family 22, conserved site" CG9118 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) " larval stage , adult stage , larval stage && pupal stage && adult stage , larval stage && adult stage " " gastric caecum

, adult midgut | anterior

, embryonic/larval midgut

, adult midgut

, anterior embryonic/larval midgut

" FBgn0266626 CR45133 http://flybase.net/reports/FBgn0266626.html non_protein_coding_gene CR45133 16-Dec-15 2015_12 FBgn0259278 EP-720 http://flybase.net/reports/FBgn0259278.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0020885 Tbf1 TE1 binding factor 1 http://flybase.net/reports/FBgn0020885.html gene 0003677=DNA binding TBF1 16-Dec-15 2015_12 FBgn0264986 CR44137 http://flybase.net/reports/FBgn0264986.html non_protein_coding_gene CR44137 16-Dec-15 2015_12 FBgn0027126 l(3)IH4 lethal (3) IH4 http://flybase.net/reports/FBgn0027126.html gene unnamed 16-Dec-15 2015_12 lethal FBgn0044017 Scad67 Suppressor of constitutively activated Dpp signaling 67 http://flybase.net/reports/FBgn0044017.html gene 0005634=nucleus 16-Dec-15 2015_12 FBgn0039970 CG17508 http://flybase.net/reports/FBgn0039970.html protein_coding_gene IPR009688=Domain of unknown function DUF1279 CG17508 16-Dec-15 2015_12 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0067752 l(1)G0187 lethal (1) G0187 http://flybase.net/reports/FBgn0067752.html gene 16-Dec-15 2015_12 lethal "wing,chaeta" FBgn0001634 l(1)dn14 lethal (1) discs normal 14 http://flybase.net/reports/FBgn0001634.html gene l(1)d.norm.-14 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039342 CG5107 http://flybase.net/reports/FBgn0039342.html FBgn0044572 protein_coding_gene anon-WO0140519.57 CG5107 16-Dec-15 2015_12 viable FBgn0021921 l(2)k11301 lethal (2) k11301 http://flybase.net/reports/FBgn0021921.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085815 CR41605 http://flybase.net/reports/FBgn0085815.html FBan0041605 rRNA_gene CR41605 16-Dec-15 2015_12 FBgn0050384 CG30384 http://flybase.net/reports/FBgn0050384.html FBgn0033150 protein_coding_gene CG11074 CG30384 16-Dec-15 2015_12 ENSMUSG00000039110(Mycbpap) viable FBgn0053062 CG33062 http://flybase.net/reports/FBgn0053062.html FBgn0062897 protein_coding_gene BcDNA:SD02058 CG33062 16-Dec-15 2015_12 FBgn0050105 CG30105 http://flybase.net/reports/FBgn0050105.html FBgn0064905 protein_coding_gene BcDNA:RE11282 "IPR013924=Ribonuclease H2, subunit C" CG30105 16-Dec-15 2015_12 ENSMUSG00000024925(Rnaseh2c) ENSG00000172922(RNASEH2C) viable DRSC05668 K 0.054141047 0.019714824 0.192379554 0.265321676 -0.273559115 1.528921631 FBgn0019661 roX1 RNA on the X 1 http://flybase.net/reports/FBgn0019661.html "FBgn0015564, FBgn0052777, FBgn0063259" non_protein_coding_gene "0009047=dosage compensation by hyperactivation of X chromosome, 0031936=negative regulation of chromatin silencing, 0007549=dosage compensation, 0016457=dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome" "0016456=X chromosome located dosage compensation complex, transcription activating, 0000805=X chromosome, 0072487=MSL complex" "BcDNA:GH10432, rox1, RNA on the X chromosome 1, chrX:3706836..3706970, yang, EG:EG0002.2, RNA on the X1, RNAonX, RoX1, roX, CR32777" CR32777 16-Dec-15 2015_12 " adult stage | male , embryonic stage | stage >=5 , larval stage | third instar , spermatogenesis && adult stage , embryonic stage | stage 5-13 " " adult fat body

, embryonic brain

, interneuron &&of antennal lobe

, neuron &&of antennal segment 3

, embryonic/larval garland cell

, ejaculatory bulb

, ring gland

, cell body &&of adult brain

, ventral nerve cord

, thoracico-abdominal ganglion

, optic lobe neuron

, pupal/adult digestive system

, photoreceptor cell

, male reproductive system

, adult brain

, embryonic/larval salivary gland

, cell body &&of mushroom body

, gastric caecum

" "viable,fertile,lethal" FBgn0000577 en engrailed http://flybase.net/reports/FBgn0000577.html "FBgn0003492, FBgn0014157, FBgn0016969" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0001158=enhancer sequence-specific DNA binding" "0007386=compartment pattern specification, 0008406=gonad development, 0035277=spiracle morphogenesis, open tracheal system, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035289=posterior head segmentation, 0007448=anterior/posterior pattern specification, imaginal disc, 0007487=analia development, 0048099=anterior/posterior lineage restriction, imaginal disc, 0007400=neuroblast fate determination, 0035288=anterior head segmentation, 0007411=axon guidance, 0007367=segment polarity determination, 0007388=posterior compartment specification, 0035290=trunk segmentation, 0007447=imaginal disc pattern formation, 0048100=wing disc anterior/posterior pattern formation, 0007485=imaginal disc-derived male genitalia development, 0007474=imaginal disc-derived wing vein specification, 0007418=ventral midline development, 0035215=genital disc development, 0021960=anterior commissure morphogenesis, 0007417=central nervous system development, 0007486=imaginal disc-derived female genitalia development, 0035224=genital disc anterior/posterior pattern formation, 0010629=negative regulation of gene expression, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated, 0010468=regulation of gene expression" 0005634=nucleus "Eng, EN, spermatheca, V, Apigmented abdomen, Invected, spt, spa2, CG9015, Engrailed/Invected, EnR, Engrailed, Engr, Erased, sparse SGPs 2, ENGRAILED, Apa, en1, En, Es, transcript group V, 153867_at" "IPR020479=Homeodomain, metazoa, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR000747=Homeodomain engrailed, IPR019737=Homeobox engrailed-type, conserved site, IPR019549=Homeobox engrailed, C-terminal, IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif" CG9015 16-Dec-15 2015_12 "ENSDARG00000015073(eng1b),ENSDARG00000014321(eng1a),ENSDARG00000026599(eng2a),ENSDARG00000068560,ENSDARG00000038868(eng2b)" "ENSG00000163064(EN1),ENSG00000164778(EN2)" " larval stage , embryonic stage--pupal stage , larval stage | third instar , embryonic stage | stage >= 6 , embryonic stage | stage 5 , embryonic stage | 3-12 hr " " ventral thoracic disc

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, dorsal metathoracic disc

,

segment polarity , dorsal mesothoracic disc

,

60% egg length " " embryonic stage | stage 11 , embryonic stage | stage 7-11 , embryonic stage , larval stage | third instar , embryonic stage | stage 8-11 , embryonic stage | stage 7 , embryonic stage | stage 8 , embryonic stage | stage >=8 , embryonic stage | stage 12-15 , embryonic stage | stage 9-11 , embryonic stage | stage 6 , embryonic stage | stage 10,11 " " ventral nervous system | posterior & segmentally repeated

, parasegment | restricted

segmentally repeated , ectoderm

, female genital disc | restricted

, neuroblast NB7-1

, parasegment 2--15

, embryonic gnathal segment | posterior <

, male genital disc | restricted

, labral segment

, intercalary segment

,

posterior | segmentally repeated , antennal segment

, epidermis | segmentally repeated

, embryonic thoracic segment | posterior <

, ectoderm

{ v arm* } , head

, neuroblast NB7-2

, embryonic abdominal segment 1--9 | posterior

, neuroblast NB7-4

, embryonic maxillary segment | posterior

, central nervous system | segmentally repeated

, embryonic maxillary segment | posterior && embryonic labial segment | posterior && embryonic thoracic segment | posterior && embryonic abdominal segment 1--7 | posterior

, neuroblast NB6-2

,

segmentally repeated , neuroblast NB6-1

, neuroblast NB1-1

" "visible,lethal,recessive,viable,sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,dominant,neuroanatomy defective,pair rule phenotype,fertile,female,reduced,lethal - all die during embryonic stage,embryonic/larval segmentation phenotype,planar polarity defective,segment polarity phenotype,some die during third instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage,partially lethal - majority die" "wing vein,anterior crossvein,posterior crossvein,wing,wing vein L5,gonad,gonadal sheath proper primordium,second segment of antenna,posterior compartment,prothoracic tibial transverse row bristle,posterior,wing vein L3,campaniform sensillum of anterior crossvein,sensillum campaniformium,scutellum,prothoracic leg,wing disc,somatic clone,anterior/posterior compartment boundary,wing vein L4,sex comb,ectopic,metathoracic tibial transverse bristle row,antenna,third segment of antenna,wing & macrochaeta,hypandrium,penis,genital arch,clasper,female gonopod,prothoracic tarsal segment,mesothoracic tarsal bristle longitudinal row 2,mesothoracic tarsal bristle longitudinal row 2.5,trichome of the posterior wing margin,alula,tergite,neuroblast NB7-3,presumptive embryonic/larval central nervous system,EL neuron,embryonic epidermis,heat sensitive,denticle belt,embryonic head,cephalopharyngeal skeleton,abdominal tergite & trichome,abdominal tergite & macrochaeta,adult abdomen,haltere,anterior compartment,male genitalia,male terminalia sensillum,hypandrial process,basal apodeme of penis,hypandrial bristle,gonopod thorn bristle,gonopod long bristle,abdominal tergite | anterior & trichome,anterior,embryonic/first instar larval cuticle,proboscis,leg,lateral plate,anal plate,central nervous system,epidermis,Keilin's organ,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,longitudinal connective,commissure,presumptive embryonic/larval muscle system,embryonic/larval central nervous system,embryonic/larval peripheral nervous system,serotonergic neuron,segment,cuticle,apodeme,embryonic/larval somatic muscle,embryonic abdomen,ventral nerve cord,posterior commissure,anterior commissure,lateral tract,metathoracic ventral denticle belt,embryonic gnathal segment,embryonic/larval fat body,stigmatophore,genital disc primordium,terminal filament,embryonic metathoracic segment,embryonic abdominal segment 2,embryonic prothoracic segment,embryonic abdominal segment 4,abdominal segment 6,abdominal segment 8,embryonic segment,cell non-autonomous,embryonic/larval cuticle,imaginal disc,embryo,spermathecum,spermathecal duct,tarsal segment,antennal sense organ,fat body/gonad primordium & parasegment 4twi.PGa,fat body/gonad primordium & parasegment 5twi.PGa,fat body/gonad primordium & parasegment 6twi.PGa,fat body/gonad primordium & parasegment 7twi.PGa,fat body/gonad primordium & parasegment 8twi.PGa,fat body/gonad primordium & parasegment 9twi.PGa,visceral mesoderm,precursor,embryonic/larval heart,fat body/gonad primordium & parasegment 6zen.Kr.PF,fat body/gonad primordium & parasegment 7zen.Kr.PF,fat body/gonad primordium & parasegment 8zen.Kr.PF,dorsal,costal cell,embryonic myoblast,embryonic/larval pericardial cell & embryonic myoblasthow-24B, twi.PG,midline glial cell,proximal,embryonic hindgut,dorsal triple row,medial triple row,ventral triple row,eye,adult head,commissure | embryonic stage,intersegmental nerve,segmental nerve,connective,RP neuron,MP1 neuron,fascicle,motor neuron & growth cone & embryo,presumptive embryonic/larval peripheral nervous system,neuromuscular junction | embryonic stage,midline neuronal primordium,UMI interneuron & axonsim.PS,VUM neuron & axonsim.PS,embryonic leading edge cell,mesothoracic tergum" FBgn0005062 fs(2)OW202 female sterile (2) OW202 http://flybase.net/reports/FBgn0005062.html gene 16-Dec-15 2015_12 FBgn0039756 CG9743 http://flybase.net/reports/FBgn0039756.html FBgn0062135 protein_coding_gene "0016717=oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water, 0004768=stearoyl-CoA 9-desaturase activity" "0006629=lipid metabolic process, 0055114=oxidation-reduction process" anon-WO0118547.264 "IPR005804=Fatty acid desaturase domain, IPR015876=Fatty acid desaturase, type 1, core" CG9743 16-Dec-15 2015_12 YGL055W(OLE1) FBgn0001986 l(2)35Df lethal (2) 35Df http://flybase.net/reports/FBgn0001986.html "FBgn0027576, FBgn0027880, FBgn0032570, FBgn0041116" protein_coding_gene "0003723=RNA binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0000398=mRNA splicing, via spliceosome, 0006401=RNA catabolic process, 0022008=neurogenesis" 0071013=catalytic step 2 spliceosome "BG:DS09217.2, cg4152, lethal(2)35Df, l.2.35Df, l(2)br44, CG4152, Mtr4, l(2)k14422, l(2)k14423, br44, BcDNA:GH07290" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR025696=rRNA-processing arch domain, IPR012961=ATP-dependent RNA helicase Ski2, C-terminal, IPR016438=ATP-dependent RNA helicase Ski2, IPR001650=Helicase, C-terminal" CG4152 16-Dec-15 2015_12 ENSDARG00000013457(skiv2l2) YJL050W(MTR4) WBGene00012342(mtr-4) ENSMUSG00000016018(Skiv2l2) ENSG00000039123(SKIV2L2) "lethal,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" "egg,macrochaeta,embryonic/larval neuroblast,ganglion mother cell" DRSC03560 E -0.699592539 0.797843571 0.337412133 -1.811410611 -0.062741721 0.669681342 FBgn0267105 CG45545 http://flybase.net/reports/FBgn0267105.html protein_coding_gene CG45545 16-Dec-15 2015_12 FBgn0016908 l(3)X27 lethal (3) X27 http://flybase.net/reports/FBgn0016908.html gene X27 16-Dec-15 2015_12 FBgn0030078 CG10970 http://flybase.net/reports/FBgn0030078.html FBgn0062471 protein_coding_gene BcDNA:HL08157 IPR001792=Acylphosphatase-like domain CG10970 16-Dec-15 2015_12 viable FBgn0029103 anon-47Ba anon-47Ba http://flybase.net/reports/FBgn0029103.html gene Fw RE 16-Dec-15 2015_12 FBgn0266894 CR45354 http://flybase.net/reports/FBgn0266894.html non_protein_coding_gene CR45354 16-Dec-15 2015_12 FBgn0083273 E(smoDN)2583 Enhancer of smoDN 2583 http://flybase.net/reports/FBgn0083273.html gene 16-Dec-15 2015_12 FBgn0263584 CR43609 http://flybase.net/reports/FBgn0263584.html non_protein_coding_gene CR43609 16-Dec-15 2015_12 FBgn0015331 abs abstrakt http://flybase.net/reports/FBgn0015331.html "FBgn0010723, FBgn0011549, FBgn0062100" protein_coding_gene "0004386=helicase activity, 0003676=nucleic acid binding, 0005524=ATP binding, 0008026=ATP-dependent helicase activity, 0008270=zinc ion binding, 0004004=ATP-dependent RNA helicase activity" "0000398=mRNA splicing, via spliceosome, 0009653=anatomical structure morphogenesis, 0006915=apoptotic process, 0007399=nervous system development, 0030010=establishment of cell polarity" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0005634=nucleus" "l(3)00620, l(3)04505, abstract, ABS, l(3)06862, l(3)06863, DmRH23, anon-WO0118547.315, Abstrakt, CG14637" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR001878=Zinc finger, CCHC-type, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG14637 16-Dec-15 2015_12 WBGene00019245(H27M09.1) ENSMUSG00000021494(Ddx41) ENSG00000183258(DDX41) embryonic stage

"lethal,recessive,heat sensitive,lethal - all die before end of larval stage,some die during third instar larval stage,wild-type,cell death defective" "retina,retina & axon,longitudinal connective,central nervous system,ommatidium,photoreceptor cell,ectopic,melanotic mass,Bolwig nerve,embryonic head,heat sensitive,nurse cell,follicle cell,pole cell,stage 5 embryo,ventral,embryonic neuroblast,neurite,spindle | heat sensitive,mitotic cell cycle | heat sensitive,egg chamber,oocyte nucleus,mesoderm,neuroblast,RP2 motor neuron,RP2sib neuron,A1-7 dorsal acute muscle 1" FBgn0015413 l(1)14Db lethal (1) 14Db http://flybase.net/reports/FBgn0015413.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266733 CR45206 http://flybase.net/reports/FBgn0266733.html non_protein_coding_gene CR45206 16-Dec-15 2015_12 FBgn0003906 tyb2 tiny bristle 2 http://flybase.net/reports/FBgn0003906.html gene tyb-2 16-Dec-15 2015_12 "visible,viable,fertile" macrochaeta FBgn0013589 l(3)97De lethal (3) 97De http://flybase.net/reports/FBgn0013589.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0085632 CG41363 http://flybase.net/reports/FBgn0085632.html FBan0041363 protein_coding_gene 16-Dec-15 2015_12 FBgn0019805 ifx iron felix http://flybase.net/reports/FBgn0019805.html gene "0008586=imaginal disc-derived wing vein morphogenesis, 0008587=imaginal disc-derived wing margin morphogenesis, 0001745=compound eye morphogenesis" 16-Dec-15 2015_12 "lethal,recessive" "wing vein,macrochaeta & wing,eye,ommatidium,wing" FBgn0067356 l(3)9358 lethal (3) 9358 http://flybase.net/reports/FBgn0067356.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043355 EP3015a EP3015a http://flybase.net/reports/FBgn0043355.html gene 16-Dec-15 2015_12 visible "scutellar bristle,ectopic,tormogen cell,trichogen cell" FBgn0045827 CG13245 http://flybase.net/reports/FBgn0045827.html "FBgn0040982, FBgn0045812, FBgn0045830" protein_coding_gene "BEST:GH21951, bs34a02.y1, BEST:GH09435, BEST:GH06096" CG13245 16-Dec-15 2015_12 viable FBgn0043471 ë¼Try ë¼Try http://flybase.net/reports/FBgn0043471.html FBgn0033620 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG12388, SPH109, kappaTry" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG12388 16-Dec-15 2015_12 FBgn0083276 E(smoDN)2576 Enhancer of smoDN 2576 http://flybase.net/reports/FBgn0083276.html gene 16-Dec-15 2015_12 FBgn0043039 l(2)42Be lethal (2) 42Be http://flybase.net/reports/FBgn0043039.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061491 lsr loser http://flybase.net/reports/FBgn0061491.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0024931 Su(var)2-1001 Su(var)2-1001 http://flybase.net/reports/FBgn0024931.html gene Su-var(2)1001 16-Dec-15 2015_12 FBgn0082356 HM274 HM274 http://flybase.net/reports/FBgn0082356.html gene 16-Dec-15 2015_12 FBgn0036702 CG6512 http://flybase.net/reports/FBgn0036702.html protein_coding_gene "0016887=ATPase activity, 0008270=zinc ion binding, 0005524=ATP binding, 0004222=metalloendopeptidase activity" "0006508=proteolysis, 0046331=lateral inhibition" "0016021=integral component of membrane, 0005783=endoplasmic reticulum, 0005739=mitochondrion" "AFG3L2, DmCG6512" "IPR011546=Peptidase M41, FtsH extracellular, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR000642=Peptidase M41, IPR005936=Peptidase, FtsH, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6512 16-Dec-15 2015_12 ENSDARG00000062272(si:ch211-12e1.4) "YMR089C(YTA12),YER017C(AFG3)" WBGene00004978(spg-7) ENSXETG00000019846(Afg3l2) "ENSMUSG00000024527(Afg3l2),ENSMUSG00000031967(Afg3l1)" ENSG00000141385(AFG3L2) "viable,visible" "chaeta,trichogen cell" FBgn0050482 CG30482 http://flybase.net/reports/FBgn0050482.html protein_coding_gene 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0051404 CG31404 http://flybase.net/reports/FBgn0051404.html FBgn0038698 protein_coding_gene CG3575 IPR006623=Testicular haploid expressed repeat CG31404 16-Dec-15 2015_12 viable FBgn0020346 anon-48Fa anon-48Fa http://flybase.net/reports/FBgn0020346.html gene 543 16-Dec-15 2015_12 FBgn0264341 CG43797 http://flybase.net/reports/FBgn0264341.html protein_coding_gene "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG43797 16-Dec-15 2015_12 FBgn0030030 CG1636 http://flybase.net/reports/FBgn0030030.html protein_coding_gene CG1636 16-Dec-15 2015_12 viable DRSC18111 IK -0.275580997 1.856855587 0.230439509 0.322116667 2.007826609 0.859828206 FBgn0001334 l(1)1Ac lethal (1) 1Ac http://flybase.net/reports/FBgn0001334.html FBgn0005413 gene "l(1)L61, l(1)J1, l(1)G11, l(1)G1, l(1)Jl, lJ1, J1, l(1)A33, l(1)Ac, l(1)RF17" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0010130 l(1)tsW1 lethal (1) tsW1 http://flybase.net/reports/FBgn0010130.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0000281 Cec2 Cecropin 2 http://flybase.net/reports/FBgn0000281.html pseudogene_attribute "CR32924, cecropin, CecPsi2, Cec, cec-Psi2, CG32934, CR32934, CG32924, Cecropin, unnamed, cecropin Psi-2, pseudo-2" CR32934 16-Dec-15 2015_12 FBgn0035260 CG7991 http://flybase.net/reports/FBgn0035260.html protein_coding_gene IPR001452=SH3 domain CG7991 16-Dec-15 2015_12 viable FBgn0030499 CG11178 http://flybase.net/reports/FBgn0030499.html protein_coding_gene 0016477=cell migration 0055037=recycling endosome IPR018307=AVL9/DENND6 domain CG11178 16-Dec-15 2015_12 ENSDARG00000055538(zgc:153609) YLR114C(AVL9) WBGene00020822(T26A5.6) ENSXETG00000021115(AVL9) ENSMUSG00000029787(Avl9) ENSG00000105778(AVL9) viable FBgn0037463 djl don juan like http://flybase.net/reports/FBgn0037463.html protein_coding_gene "0005634=nucleus, 0016007=mitochondrial derivative, 0036126=sperm flagellum" "dj like, dj-like, Don Juan-like, CG1984" CG1984 16-Dec-15 2015_12 "male fertile,viable" FBgn0267126 CR45566 http://flybase.net/reports/FBgn0267126.html non_protein_coding_gene CR45566 16-Dec-15 2015_12 FBgn0069248 attP:Dps3 pseudo attP recognition site Dps3 http://flybase.net/reports/FBgn0069248.html region 16-Dec-15 2015_12 FBgn0053340 CG33340 http://flybase.net/reports/FBgn0053340.html "FBgn0039191, FBgn0046281, FBgn0061428" protein_coding_gene "BcDNA:AT31672, CG13612, BEST:GH24664" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG33340 16-Dec-15 2015_12 viable FBgn0083308 E(smoDN)1438 Enhancer of smoDN 1438 http://flybase.net/reports/FBgn0083308.html gene 16-Dec-15 2015_12 FBgn0264409 FCE-B http://flybase.net/reports/FBgn0264409.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0260042 circe circe http://flybase.net/reports/FBgn0260042.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0003881 tu(3)C4 tumor(3)C4 http://flybase.net/reports/FBgn0003881.html gene tu-C4 16-Dec-15 2015_12 FBgn0029643 CG14420 http://flybase.net/reports/FBgn0029643.html protein_coding_gene CG14420 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" DRSC25167 IEK 0.848598515 2.454644649 2.30721626 -0.767427185 2.414727452 -0.263012826 FBgn0000045 Act79B Actin 79B http://flybase.net/reports/FBgn0000045.html protein_coding_gene 0005200=structural constituent of cytoskeleton 0007010=cytoskeleton organization 0005884=actin filament "actin-79B, D, mus79B, act 79B, Actin, F-actin, CG7478, 143060_f_at, 79B Actin, actin, act79B" "IPR020902=Actin/actin-like conserved site, IPR004000=Actin family, IPR004001=Actin, conserved site" CG7478 16-Dec-15 2015_12 YFL039C(ACT1) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC11604 IEK -0.483749854 -2.954443186 0.425419399 -1.522535291 1.731784002 0.937078932 FBgn0263005 CG43313 http://flybase.net/reports/FBgn0263005.html "FBgn0030448, FBgn0040862" protein_coding_gene 0008376=acetylgalactosaminyltransferase activity 0032580=Golgi cisterna membrane "CG12714, dCHPF, CG4351" IPR008428=Chondroitin N-acetylgalactosaminyltransferase CG43313 16-Dec-15 2015_12 ENSDARG00000059961(wu:fj34h01) WBGene00003253(mig-22) ENSXETG00000014413() "ENSMUSG00000038181,ENSMUSG00000032997(Chpf)" "ENSG00000123989(CHPF),ENSG00000033100(CHPF2)" FBgn0001866 l(1)X10 lethal (1) X10 http://flybase.net/reports/FBgn0001866.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0016713 Reg-18 Rhythmically expressed gene 18 http://flybase.net/reports/FBgn0016713.html gene "Drosophila Rhythmically expressed gene 18, Dreg-18" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " adult head

FBgn0267648 pre-mod(mdg4)-G http://flybase.net/reports/FBgn0267648.html protein_coding_gene CG45986 CG45986 16-Dec-15 2015_12 FBgn0067762 l(1)E-81 lethal (1) E-81 http://flybase.net/reports/FBgn0067762.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002468 l(3)SG23 lethal (3) SG23 http://flybase.net/reports/FBgn0002468.html gene l(3)g49 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0034521 Mgat1 "Mannosyl (ë±-1,3-)-glycoprotein ë_-1,2-N-acetylglucosaminyltransferase 1" http://flybase.net/reports/FBgn0034521.html protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0003827=alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity" "0008344=adult locomotory behavior, 0018279=protein N-linked glycosylation via asparagine, 0008340=determination of adult lifespan, 0016319=mushroom body development, 0006487=protein N-linked glycosylation, 0035010=encapsulation of foreign target" 0005797=Golgi medial cisterna "N-acetylglucosaminyltransferase I, dMGAT1, GlcNAc-TI, GlcNAcT1, CG13431, UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1, MGAT1" "IPR004139=Glycosyl transferase, family 13, IPR029044=Nucleotide-diphospho-sugar transferases" CG13431 16-Dec-15 2015_12 "ENSDARG00000012407(zgc:66030),ENSDARG00000036065(zgc:153912)" "WBGene00001638(gly-13),WBGene00001639(gly-14)" ENSXETG00000019026(Q5M7Q5_XENTR) ENSMUSG00000020346(Mgat1) ENSG00000131446(MGAT1) "immune response defective,long lived,RU486 conditional,oxidative stress response defective,short lived,locomotor behavior defective,viable,conditional,hypoactive,recessive,male sterile,female fertile,female,male,neuroanatomy defective,dominant" mushroom body beta-lobe FBgn0017447 anon-14Ca anon-14Ca http://flybase.net/reports/FBgn0017447.html gene unnamed 16-Dec-15 2015_12 FBgn0050240 tRNA:CR30240 transfer RNA:CR30240 http://flybase.net/reports/FBgn0050240.html "FBgn0011847, FBgn0060237" tRNA_gene "0033459=GAA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:E4:53A, tRNA:Glu, tRNA:E:TTC:AE002787-e, tRNA:glu4:53A, transfer RNA:glu4:53A, CR30240, chr2R.trna26-GluTTC, AE002787.trna43-GluTTC" CR30240 16-Dec-15 2015_12 FBgn0003671 tbr tracheae broken http://flybase.net/reports/FBgn0003671.html gene tb 16-Dec-15 2015_12 viable embryonic/larval tracheal system FBgn0015877 anon-48Af anon-48Af http://flybase.net/reports/FBgn0015877.html gene "VIII, transcript group VIII" 16-Dec-15 2015_12 FBgn0267300 CR45736 http://flybase.net/reports/FBgn0267300.html non_protein_coding_gene CR45736 16-Dec-15 2015_12 FBgn0265744 CR44551 http://flybase.net/reports/FBgn0265744.html non_protein_coding_gene CR44551 16-Dec-15 2015_12 FBgn0062627 Mod(var)1044 Mod(var)1044 http://flybase.net/reports/FBgn0062627.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1044 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0039577 CG12516 http://flybase.net/reports/FBgn0039577.html protein_coding_gene IPR009961=Protein of unknown function DUF1487 CG12516 16-Dec-15 2015_12 FBgn0266778 CR45243 http://flybase.net/reports/FBgn0266778.html non_protein_coding_gene CR45243 16-Dec-15 2015_12 FBgn0267933 CR46213 http://flybase.net/reports/FBgn0267933.html non_protein_coding_gene lincRNA.565 CR46213 16-Dec-15 2015_12 FBgn0015007 Abl::Mmus\Abl Abl http://flybase.net/reports/FBgn0015007.html engineered_fusion_gene Abl::Mus\Abl 16-Dec-15 2015_12 FBgn0266212 CR44907 http://flybase.net/reports/FBgn0266212.html non_protein_coding_gene CR44907 16-Dec-15 2015_12 FBgn0035385 FMRFaR FMRFamide Receptor http://flybase.net/reports/FBgn0035385.html protein_coding_gene "0004985=opioid receptor activity, 0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity, 0001653=peptide receptor activity" "0008345=larval locomotory behavior, 0007218=neuropeptide signaling pathway, 0002209=behavioral defense response, 0007186=G-protein coupled receptor signaling pathway, 0008344=adult locomotory behavior" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "FR, FMRFaR, Fmrf Receptor, CG2114, larval-opioid-receptor, Fmrf receptor, FMRFamide receptor, FMRFa-R, Dm FMRFa-R, DrmFMRFa-R, dFMRFa receptor, FMRFa-receptor" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG2114 16-Dec-15 2015_12 "WBGene00020586(T19F4.1),WBGene00016909(C54A12.2),WBGene00017661(F21C10.12),WBGene00020023(R12C12.3)" "viable,fertile" FBgn0086049 snoRNA:Me28S-U3344a http://flybase.net/reports/FBgn0086049.html snoRNA_gene "mg28S-3344, MeS8SU3344a, Me28S-Um3344a, CR34678" CR34678 16-Dec-15 2015_12 FBgn0259227 CG42327 http://flybase.net/reports/FBgn0259227.html "FBgn0037928, FBgn0037929, FBgn0037927, FBgn0061730" protein_coding_gene 0004725=protein tyrosine phosphatase activity 0006470=protein dephosphorylation "anon-WO0118547.710, CG14713, CG18479, CG14714" "IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site, IPR000242=PTP type protein phosphatase, IPR000387=Tyrosine specific protein phosphatases domain" CG42327 16-Dec-15 2015_12 DRSC14937 E -0.701053665 0.902262282 4.131896222 0.299274902 0.971734764 -0.102033293 FBgn0267140 CR45580 http://flybase.net/reports/FBgn0267140.html non_protein_coding_gene CR45580 16-Dec-15 2015_12 FBgn0050093 COX6AL Cytochrome c oxidase subunit 6A-like http://flybase.net/reports/FBgn0050093.html FBgn0045432 protein_coding_gene 0004129=cytochrome-c oxidase activity 0005751=mitochondrial respiratory chain complex IV "Cytochrome c oxidase polypeptide VIa, Cytochrome c oxidase Polypeptide VIA, COXD, NEST:bs02a12, COXE, CG30093" "IPR001349=Cytochrome c oxidase, subunit VIa" CG30093 16-Dec-15 2015_12 YGL191W(COX13) WBGene00006519(tag-174) viable FBgn0067342 l(3)L3F lethal (3) L3F http://flybase.net/reports/FBgn0067342.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027281 l(1)G0191 lethal (1) G0191 http://flybase.net/reports/FBgn0027281.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0259414 EP-17 http://flybase.net/reports/FBgn0259414.html gene 16-Dec-15 2015_12 visible wing vein FBgn0038271 UQCR-C1 Ubiquinol-cytochrome c reductase core protein 1 http://flybase.net/reports/FBgn0038271.html protein_coding_gene "0008121=ubiquinol-cytochrome-c reductase activity, 0004222=metalloendopeptidase activity, 0046872=metal ion binding" "0006122=mitochondrial electron transport, ubiquinol to cytochrome c, 0031122=cytoplasmic microtubule organization, 0016485=protein processing" "0005750=mitochondrial respiratory chain complex III, 0005759=mitochondrial matrix, 0005875=microtubule associated complex, 0005739=mitochondrion, 0005811=lipid particle, 0017087=mitochondrial processing peptidase complex" "CG3731, CG 3731, MPPB, Ubiquinol-cytochrome c reductase Core protein 1, Ubiquinol-cytochrome c oxidoreductase Core protein 1, UCR1, Mitochondrial processing peptidase beta subunit, Ubiquinol-cytochrome C reductase complex core protein I" "IPR011765=Peptidase M16, N-terminal, IPR011237=Peptidase M16 domain, IPR007863=Peptidase M16, C-terminal, IPR011249=Metalloenzyme, LuxS/M16 peptidase-like, IPR001431=Peptidase M16, zinc-binding site" CG3731 16-Dec-15 2015_12 ENSDARG00000016979(pmpcb) YLR163C(MAS1) WBGene00013880(mppb-1) ENSXETG00000023106(pmpcb) ENSMUSG00000029017(Pmpcb) ENSG00000105819(PMPCB) "viable,fertile,visible,lethal" mesothoracic tergum DRSC15508 K -0.645110582 -0.598806369 -1.21188733 -1.255991359 1.78948517 -0.095624857 FBgn0024664 l(2)k06020 lethal (2) k06020 http://flybase.net/reports/FBgn0024664.html gene 60/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0024986 CG3719 http://flybase.net/reports/FBgn0024986.html "FBgn0029575, FBgn0063169" protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" "0006662=glycerol ether metabolic process, 0045454=cell redox homeostasis" 0005739=mitochondrion "EG:132E8.3, thioredoxin, BcDNA:LD03613" "IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold, IPR005746=Thioredoxin" CG3719 16-Dec-15 2015_12 "viable,fertile,lethal,recessive" FBgn0086070 snoRNA:Or-CD11c http://flybase.net/reports/FBgn0086070.html snoRNA_gene "CR34699, orphan CD11c" CR34699 16-Dec-15 2015_12 FBgn0060917 l(3)S042610 lethal (3) S042610 http://flybase.net/reports/FBgn0060917.html gene 0426/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0021955 l(2)k10237 lethal (2) k10237 http://flybase.net/reports/FBgn0021955.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015011 Ahcy89E Adenosylhomocysteinase 89E http://flybase.net/reports/FBgn0015011.html protein_coding_gene 0004013=adenosylhomocysteinase activity 0006730=one-carbon metabolic process "S-AHCY, AdoHcyase-like, AHCY, CG8956, pH200, S-adenosyl homocysteine hydrolase-like" "IPR000043=Adenosylhomocysteinase, IPR020082=S-adenosyl-L-homocysteine hydrolase, conserved site, IPR016040=NAD(P)-binding domain, IPR015878=S-adenosyl-L-homocysteine hydrolase, NAD binding domain" CG8956 16-Dec-15 2015_12 "ENSXETG00000002023(AHCYL1),ENSXETG00000014902(BC090609.1)" embryonic stage " embryonic/larval midgut

, somatic mesoderm

" viable FBgn0014193 hty hypersprouty http://flybase.net/reports/FBgn0014193.html gene 16-Dec-15 2015_12 FBgn0263490 mld molting defective http://flybase.net/reports/FBgn0263490.html "FBan0013620, FBgn0083077, FBgn0033118, FBgn0039211, FBgn0051312, FBgn0053343, FBgn0002416" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "0006697=ecdysone biosynthetic process, 0008340=determination of adult lifespan, 0045938=positive regulation of circadian sleep/wake cycle, sleep, 0007616=long-term memory" 0005634=nucleus "CG33343, CG13620, Dominant temperature-sensitive 3, l(3)3[DTS], l(3)DTS3, CG9469, L(3)3[DTS], defective, lethal (3) DTS3, molting, Mld, CG31312, Molting defective, DTS-3, CG34100" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG34100 16-Dec-15 2015_12 FBgn0044045 J3220 J3220 http://flybase.net/reports/FBgn0044045.html gene 0007389=pattern specification process 16-Dec-15 2015_12 FBgn0266768 CR45233 http://flybase.net/reports/FBgn0266768.html non_protein_coding_gene CR45233 16-Dec-15 2015_12 FBgn0262269 mir-955 mir-955 stem loop http://flybase.net/reports/FBgn0262269.html miRNA_gene "miR-955, CR42976" CR42976 16-Dec-15 2015_12 viable FBgn0064243 EP3617 EP3617 http://flybase.net/reports/FBgn0064243.html gene 16-Dec-15 2015_12 visible eye FBgn0266667 Exo70 Exo70 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266667.html "FBgn0266607, FBgn0035892" protein_coding_gene "0008013=beta-catenin binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding" "0006887=exocytosis, 0016081=synaptic vesicle docking, 0016192=vesicle-mediated transport, 0007269=neurotransmitter secretion, 0016080=synaptic vesicle targeting" 0000145=exocyst "Exo70p, CG7127, exo70" "IPR004140=Exocyst complex protein Exo70, IPR016159=Cullin repeat-like-containing domain" CG7127 16-Dec-15 2015_12 ENSDARG00000055932 WBGene00016606(exoc-7) ENSXETG00000019551(EXOC7) ENSMUSG00000020792(Exoc7) ENSG00000182473(EXOC7) FBgn0010033 E(var)21 E(var)21 http://flybase.net/reports/FBgn0010033.html gene 16-Dec-15 2015_12 FBgn0003669 tbd tiny bristloid http://flybase.net/reports/FBgn0003669.html gene tiny bristleoid 16-Dec-15 2015_12 "small body,viable,fertile" macrochaeta FBgn0060568 l(3)S096507b lethal (3) S096507b http://flybase.net/reports/FBgn0060568.html gene 0965/07 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037609 CG9773 http://flybase.net/reports/FBgn0037609.html protein_coding_gene IPR007881=UNC-50 CG9773 16-Dec-15 2015_12 ENSDARG00000040455(unc50) YKR030W(GMH1) WBGene00006785(unc-50) ENSXETG00000026564(UNC50) ENSMUSG00000026111(Unc50) ENSG00000115446(UNC50) FBgn0005320 ney narrow eye http://flybase.net/reports/FBgn0005320.html gene unnamed 16-Dec-15 2015_12 "visible,recessive,viable,fertile" eye FBgn0034153 Acp53C14b Accessory gland protein 53C14b http://flybase.net/reports/FBgn0034153.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG15616, Acp53Cb, Acp53, Acp53C14b" IPR009392=Drosophila ACP53EA CG15616 16-Dec-15 2015_12 "viable,fertile" FBgn0034833 CG13539 http://flybase.net/reports/FBgn0034833.html protein_coding_gene IPR009961=Protein of unknown function DUF1487 CG13539 16-Dec-15 2015_12 viable FBgn0065329 l(2)SH1890 lethal (2) SH1890 http://flybase.net/reports/FBgn0065329.html gene l(2)SH2 1890 16-Dec-15 2015_12 "lethal,recessive" FBgn0001450 l(1)7Dd lethal (1) 7Dd http://flybase.net/reports/FBgn0001450.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0265195 veg vegetable http://flybase.net/reports/FBgn0265195.html FBgn0015562 gene 0007422=peripheral nervous system development "CG6657, lethal (2) k01206, l(2)k01206" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" "presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,fascicle,presumptive embryonic/larval central nervous system" FBgn0004114 Su(var)303 Suppressor of variegation 303 http://flybase.net/reports/FBgn0004114.html gene 16-Dec-15 2015_12 FBgn0004211 l(3)84Ei lethal (3) 84Ei http://flybase.net/reports/FBgn0004211.html gene 16-Dec-15 2015_12 lethal FBgn0002642 Malf Malformed http://flybase.net/reports/FBgn0002642.html gene Mal 16-Dec-15 2015_12 "visible,viable,dominant" "eye,ommatidium" FBgn0262542 CR43096 http://flybase.net/reports/FBgn0262542.html pseudogene_attribute CR43096 16-Dec-15 2015_12 FBgn0028320 l(1)G0343 lethal (1) G0343 http://flybase.net/reports/FBgn0028320.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002199 l(3)67Ac lethal (3) 67Ac http://flybase.net/reports/FBgn0002199.html gene 16-Dec-15 2015_12 "visible,lethal,recessive,some die during immature adult stage" "eye,wing" FBgn0031741 CG11034 http://flybase.net/reports/FBgn0031741.html protein_coding_gene "0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0016020=membrane "IPR029058=Alpha/Beta hydrolase fold, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469=Dipeptidylpeptidase IV, N-terminal domain" CG11034 16-Dec-15 2015_12 "YHR028C(DAP2),YOR219C(STE13)" WBGene00001054(dpf-1) "ENSG00000197635(DPP4),ENSG00000078098(FAP)" viable DRSC02122 K -0.071220947 0.43645371 -0.297776783 0.530207358 1.630051079 0.054299364 FBgn0000886 fs(1)M84 female sterile (1) M84 http://flybase.net/reports/FBgn0000886.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0022040 l(2)k08320 lethal (2) k08320 http://flybase.net/reports/FBgn0022040.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036715 Cad74A Cadherin 74A http://flybase.net/reports/FBgn0036715.html protein_coding_gene "0042803=protein homodimerization activity, 0005509=calcium ion binding" "0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0046843=dorsal appendage formation, 0044331=cell-cell adhesion mediated by cadherin, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" "0016324=apical plasma membrane, 0005887=integral component of plasma membrane, 0005902=microvillus" "CT20086, cad74A, DCad74B, CG6445, Cad74B, Cad74A" "IPR020894=Cadherin conserved site, IPR002126=Cadherin, IPR015919=Cadherin-like" CG6445 16-Dec-15 2015_12 WBGene00017576(cdh-8) ENSMUSG00000034918(Cdhr2) "viable,fertile,body color defective" "dorsal appendage,follicle cell,egg chamber,mesothoracic tergum" FBgn0002073 l(2)49Fb lethal (2) 49Fb http://flybase.net/reports/FBgn0002073.html FBgn0002076 gene "l(2)vr8, l(2)vr4, vr-4, vr-8, vr8, vr4, l(2)49Fe" 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation,dominant,viable" FBgn0020855 fs(2)C10 fs(2)C10 http://flybase.net/reports/FBgn0020855.html gene 2-C10 16-Dec-15 2015_12 "chemical sensitive,recessive,female sterile" FBgn0066331 prx Pavlov's Rex http://flybase.net/reports/FBgn0066331.html gene "0008355=olfactory learning, 0007611=learning or memory" "rex, Rex" 16-Dec-15 2015_12 memory defective FBgn0086423 l(3)CHg lethal (3) CHg http://flybase.net/reports/FBgn0086423.html gene complementation group 9 16-Dec-15 2015_12 "lethal,recessive" FBgn0261296 GJ20676 http://flybase.net/reports/FBgn0261296.html protein_coding_gene "heat-shock factor, HSF" 16-Dec-15 2015_12 FBgn0267793 CR45232 http://flybase.net/reports/FBgn0267793.html "FBgn0262946, FBgn0266767" non_protein_coding_gene "CG43265, mdcds_12606" CR45232 16-Dec-15 2015_12 FBgn0262392 mir-1004 mir-1004 stem loop http://flybase.net/reports/FBgn0262392.html "FBgn0250800, FBgn0262219" miRNA_gene "miR-1004, CR42926, dme-mir-1004" CR42926 16-Dec-15 2015_12 viable FBgn0037298 CG2604 http://flybase.net/reports/FBgn0037298.html protein_coding_gene 0016491=oxidoreductase activity "0035220=wing disc development, 0022416=chaeta development, 0055114=oxidation-reduction process" 0005811=lipid particle "Saccheropin dehydrogenase, CT40966" "IPR016040=NAD(P)-binding domain, IPR005097=Saccharopine dehydrogenase, NADP binding domain" CG2604 16-Dec-15 2015_12 "ENSDARG00000024564(sccpdhb),ENSDARG00000033665,ENSDARG00000014512" "WBGene00017719(F22F7.1),WBGene00017720(F22F7.2)" ENSXETG00000007895(SCCPDH) ENSMUSG00000038936(Sccpdh) ENSG00000143653(SCCPDH) viable "wing vein,ectopic" DRSC29919 K -0.200320031 -0.703547224 -0.168330664 0.069099755 -1.234252589 2.70731242 FBgn0266244 CR44939 http://flybase.net/reports/FBgn0266244.html non_protein_coding_gene CR44939 16-Dec-15 2015_12 FBgn0052626 AMPdeam AMP deaminase http://flybase.net/reports/FBgn0052626.html "FBgn0030531, FBgn0040867, FBgn0040868" protein_coding_gene "0005515=protein binding, 0003876=AMP deaminase activity" 0032264=IMP salvage 0005829=cytosol "CG32626, unnamed, CG11058, AMP deam, CG15762, CG11065" "IPR001365=Adenosine/AMP deaminase domain, IPR006650=Adenosine/AMP deaminase active site, IPR006329=AMP deaminase" CG32626 16-Dec-15 2015_12 ENSDARG00000029952(ampd2) YML035C(AMD1) WBGene00016415(C34F11.3) ENSXETG00000002009(AMPD2) ENSMUSG00000027889(Ampd2) ENSG00000116337(AMPD2) "partially lethal - majority die,some die during pupal stage,viable" DRSC19368 I 0.596557059 3.058047761 1.002544423 -0.715926298 -1.109213934 -0.085549501 FBgn0023065 l(1)20Bd lethal (1) 20Bd http://flybase.net/reports/FBgn0023065.html gene C2/5.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0053446 5SrRNA:CR33446 5SrRNA:CR33446 http://flybase.net/reports/FBgn0053446.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33446 CR33446 16-Dec-15 2015_12 FBgn0052176 CG32176 http://flybase.net/reports/FBgn0052176.html "FBgn0036722, FBgn0036724, FBtr0075218, FBpp0074980" protein_coding_gene "CG13730, CG13729" CG32176 16-Dec-15 2015_12 "viable,fertile,planar polarity defective" FBgn0062255 Su(Sd)2a-1 Suppressor of SD 2a-1 http://flybase.net/reports/FBgn0062255.html gene Su(SD)[2a-1] 16-Dec-15 2015_12 "lethal,recessive" FBgn0259589 B0193 http://flybase.net/reports/FBgn0259589.html gene 16-Dec-15 2015_12 visible "anterior crossvein,antennal segment,arista,tarsal segment" FBgn0084970 gloin gloin http://flybase.net/reports/FBgn0084970.html gene "0007428=primary branching, open tracheal system" glo 16-Dec-15 2015_12 "presumptive embryonic/larval tracheal system,visceral branch primordium,dorsal trunk primordium,tracheal system" FBgn0262539 CG43093 http://flybase.net/reports/FBgn0262539.html protein_coding_gene CG43093 16-Dec-15 2015_12 FBgn0037369 CG2100 http://flybase.net/reports/FBgn0037369.html protein_coding_gene "0003723=RNA binding, 0004652=polynucleotide adenylyltransferase activity" "0022008=neurogenesis, 0006396=RNA processing" "IPR002646=Poly A polymerase, head domain" CG2100 16-Dec-15 2015_12 ENSDARG00000019577(LOC100329605) YER168C(CCA1) WBGene00010089(F55B12.4) ENSXETG00000025091(Q6P873_XENTR) ENSMUSG00000013736(Trnt1) ENSG00000072756(TRNT1) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0259615 B1515 http://flybase.net/reports/FBgn0259615.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030459 CG12723 http://flybase.net/reports/FBgn0030459.html protein_coding_gene CG12723 16-Dec-15 2015_12 viable FBgn0259236 comm3 comm3 http://flybase.net/reports/FBgn0259236.html "FBgn0053209, FBgn0036521, FBgn0036523, FBgn0036524" protein_coding_gene "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" "CG13446, CG13447, CG42334, CG13448, CG33209" CG42334 16-Dec-15 2015_12 FBgn0031693 Cyp4ac1 Cyp4ac1 http://flybase.net/reports/FBgn0031693.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" "0042445=hormone metabolic process, 0046701=insecticide catabolic process, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "cyp4ac1, 4ac1, CG14032" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG14032 16-Dec-15 2015_12 YDR402C(DIT2) FBgn0001127 gp gap http://flybase.net/reports/FBgn0001127.html gene 16-Dec-15 2015_12 visible wing vein L4 FBgn0034435 CG9975 http://flybase.net/reports/FBgn0034435.html protein_coding_gene "0032504=multicellular organism reproduction, 0022008=neurogenesis" 0005615=extracellular space CG9975 16-Dec-15 2015_12 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval neuroblast FBgn0034975 enok enoki mushroom http://flybase.net/reports/FBgn0034975.html "FBgn0023464, FBgn0061181" protein_coding_gene "0004402=histone acetyltransferase activity, 0003677=DNA binding, 0008270=zinc ion binding" "0016319=mushroom body development, 0007405=neuroblast proliferation, 0006355=regulation of transcription, DNA-templated, 2000737=negative regulation of stem cell differentiation, 0006334=nucleosome assembly, 0016573=histone acetylation, 0033563=dorsal/ventral axon guidance, 0036099=female germ-line stem cell maintenance, 0046425=regulation of JAK-STAT cascade" "0000786=nucleosome, 0000123=histone acetyltransferase complex" "anon-WO0200864.1, Enoki mushroom, Enok, Cg11290, S1, CG11290, KAT6, anon-WO0200864.2, rotkehlchen, anon-60Ba, dmHAG406, unnamed, rot" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR005818=Linker histone H1/H5, domain H15, IPR001965=Zinc finger, PHD-type, IPR002717=Histone acetyltransferase domain, MYST-type, IPR016181=Acyl-CoA N-acyltransferase, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG11290 16-Dec-15 2015_12 "ENSDARG00000055429,ENSDARG00000018907(myst3)" ENSXETG00000016797(MYST3) "ENSMUSG00000021767(Myst4),ENSMUSG00000031540(Myst3)" "ENSG00000083168(KAT6A),ENSG00000156650(KAT6B)" "neuroanatomy defective,somatic clone,size defective,female semi-sterile,germline clone,lethal,recessive,viable,visible" "female germline stem cell,progressive,heat sensitive,germarium cap cell,germline clone,axon | somatic clone | third instar larval stage,somatic clone,adult mushroom body,mesothoracic tergum" FBgn0029018 l(3)77CDg lethal (3) 77CDg http://flybase.net/reports/FBgn0029018.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015021 Chap50 Chromosome-associated protein 50kD http://flybase.net/reports/FBgn0015021.html gene 0003682=chromatin binding unnamed 16-Dec-15 2015_12 FBgn0037766 Teh1 tipE homolog 1 http://flybase.net/reports/FBgn0037766.html protein_coding_gene 0017080=sodium channel regulator activity 0002028=regulation of sodium ion transport 0016021=integral component of membrane "CG12806, TEH1" CG12806 16-Dec-15 2015_12 viable FBgn0005664 Crys Crystallin http://flybase.net/reports/FBgn0005664.html protein_coding_gene "0005212=structural constituent of eye lens, 0005214=structural constituent of chitin-based cuticle, 0005509=calcium ion binding" "0007601=visual perception, 0048058=compound eye corneal lens development" "0005576=extracellular region, 0031012=extracellular matrix" "CG16963, crystallin, dcy, Cyrstallin, droscrystallin, drosocrystallin, DmelCry, Cry, Ddosocrystallin, c, Drosocrystallin" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG16963 16-Dec-15 2015_12 " pupal stage , pharate adult stage | stage P10-15 " " cone cell

, organism

, ocellus retinula cell

, primary pigment cell

, ocellus corneagenous cell

, ocellus

" " adult stage , pupal stage | mid-late " " cornea

, lens

, primary pigment cell

" viable FBgn0036994 CG5199 http://flybase.net/reports/FBgn0036994.html protein_coding_gene "0071630=nucleus-associated proteasomal ubiquitin-dependent protein catabolic process, 0031144=proteasome localization" 0031965=nuclear membrane CUT8 IPR013868=Tethering factor for nuclear proteasome Cut8/Sts1 CG5199 16-Dec-15 2015_12 viable FBgn0037875 ZnT86D Zinc transporter 86D http://flybase.net/reports/FBgn0037875.html protein_coding_gene 0005385=zinc ion transmembrane transporter activity "0006812=cation transport, 0055085=transmembrane transport" "0005622=intracellular, 0016021=integral component of membrane, 0016323=basolateral plasma membrane, 0005794=Golgi apparatus" "cg6672, dZnT7, CG6672, dZnT86D" "IPR027469=Cation efflux protein transmembrane domain, IPR002524=Cation efflux protein" CG6672 16-Dec-15 2015_12 ENSDARG00000019998(slc30a7) ENSXETG00000025164(slc30a7) ENSMUSG00000054414(Slc30a7) ENSG00000162695(SLC30A7) "viable,visible,developmental rate defective,lethal - all die before end of larval stage,body color defective,lethal - all die during larval stage" eye FBgn0044422 M82-19 M82-19 http://flybase.net/reports/FBgn0044422.html gene 0001754=eye photoreceptor cell differentiation 16-Dec-15 2015_12 viable FBgn0002006 l(2)36Ca lethal (2) 36Ca http://flybase.net/reports/FBgn0002006.html gene "l(2)HT-1, l(2L)HT-1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0039325 CG10560 http://flybase.net/reports/FBgn0039325.html protein_coding_gene "IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain" CG10560 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" "viable,fertile,lethal" FBgn0260014 nds indios http://flybase.net/reports/FBgn0260014.html gene 16-Dec-15 2015_12 "chorion,dorsal appendage,chorion | germline clone" FBgn0022012 l(2)k09107 lethal (2) k09107 http://flybase.net/reports/FBgn0022012.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032069 LManVI Lysosomal ë±-mannosidase VI http://flybase.net/reports/FBgn0032069.html protein_coding_gene "0030246=carbohydrate binding, 0008270=zinc ion binding, 0004559=alpha-mannosidase activity" 0006013=mannose metabolic process 0005764=lysosome "CG9468, LManVI" "IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR015341=Glycoside hydrolase, family 38, central domain, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR011013=Galactose mutarotase-like domain, IPR000602=Glycoside hydrolase family 38, N-terminal domain, IPR027291=Glycoside hydrolase 38/57, N-terminal domain" CG9468 16-Dec-15 2015_12 WBGene00018877(aman-1) ENSXETG00000011609(MAN2B2) viable DRSC03224 I 1.522227275 1.555148586 1.411921477 -0.442056916 -0.4299295 0.315761799 FBgn0035710 SP1173 SP1173 http://flybase.net/reports/FBgn0035710.html protein_coding_gene CG10121 IPR020846=Major facilitator superfamily domain CG10121 16-Dec-15 2015_12 "viable,fertile" FBgn0060458 l(3)S117902 lethal (3) S117902 http://flybase.net/reports/FBgn0060458.html gene 1179/02 16-Dec-15 2015_12 lethal FBgn0032818 CG10628 http://flybase.net/reports/FBgn0032818.html protein_coding_gene "0003924=GTPase activity, 0000287=magnesium ion binding, 0005525=GTP binding" "IPR031167=OBG-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014100=GTP-binding protein Obg/CgtA, IPR006073=GTP binding domain, IPR006169=GTP1/OBG domain" CG10628 16-Dec-15 2015_12 ENSDARG00000040300(gtpbp10) WBGene00016145(C26E6.12) ENSXETG00000007436(BC087811.1) ENSMUSG00000040464(Gtpbp10) ENSG00000105793(GTPBP10) "viable,visible" trichogen cell DRSC02080 IE 2.75036691 -0.201003573 4.769571053 -0.300649533 0.770052649 -0.581744254 FBgn0023418 8H11 8H11 http://flybase.net/reports/FBgn0023418.html gene 0007411=axon guidance 16-Dec-15 2015_12 FBgn0266199 CR44894 http://flybase.net/reports/FBgn0266199.html non_protein_coding_gene CR44894 16-Dec-15 2015_12 FBgn0028474 CG4119 http://flybase.net/reports/FBgn0028474.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005634=nucleus" "BcDNA:LD23634, cg4119" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain, IPR002483=PWI domain" CG4119 16-Dec-15 2015_12 "ENSDARG00000006395(rbm25),ENSDARG00000039266" ENSXETG00000021857(rbm25) ENSMUSG00000010608(Rbm25) ENSG00000119707(RBM25) viable FBgn0036187 RIOK1 RIO kinase 1 http://flybase.net/reports/FBgn0036187.html protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0022008=neurogenesis, 0040018=positive regulation of multicellular organism growth, 0060252=positive regulation of glial cell proliferation, 0090277=positive regulation of peptide hormone secretion, 0009267=cellular response to starvation, 0006468=protein phosphorylation" "0005634=nucleus, 0005737=cytoplasm" "dRIOK1, Rio1, CG11660" "IPR011009=Protein kinase-like domain, IPR018935=RIO kinase, conserved site, IPR017407=Serine/threonine-protein kinase Rio1, IPR000687=RIO kinase" CG11660 16-Dec-15 2015_12 ENSDARG00000016399(riok1) YOR119C(RIO1) WBGene00019698(riok-1) ENSXETG00000020436(RIOK1) ENSMUSG00000021428(Riok1) ENSG00000124784(RIOK1) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001543 l(1)14Fa lethal (1) 14Fa http://flybase.net/reports/FBgn0001543.html gene "16f, l(1)16f" 16-Dec-15 2015_12 lethal FBgn0002755 mit(1)5 mitotic 5 http://flybase.net/reports/FBgn0002755.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0261294 CheB74a Chemosensory protein B 74a http://flybase.net/reports/FBgn0261294.html "FBgn0067308, FBgn0053924" protein_coding_gene 0008289=lipid binding "0007606=sensory perception of chemical stimulus, 0043695=detection of pheromone" "0005576=extracellular region, 0005615=extracellular space" "CheB74a, CG33924" CG33924 16-Dec-15 2015_12 FBgn0025130 su(RpII140Z36)S17 su(RpII140Z36)S17 http://flybase.net/reports/FBgn0025130.html gene Z36[S17] 16-Dec-15 2015_12 FBgn0024328 Methyl-transferase-like Methyl transferase like http://flybase.net/reports/FBgn0024328.html gene 0008168=methyltransferase activity 16-Dec-15 2015_12 FBgn0005295 mei-2593 meiotic 2593 http://flybase.net/reports/FBgn0005295.html gene 2593 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0020515 A3 A3 http://flybase.net/reports/FBgn0020515.html gene 0008105=asymmetric protein localization 0005886=plasma membrane 16-Dec-15 2015_12 FBgn0020790 pyg pygoscelis http://flybase.net/reports/FBgn0020790.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces "pomp, pen, penguin, pompholyx" 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0029804 CG3097 http://flybase.net/reports/FBgn0029804.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR009020=Proteinase inhibitor, propeptide, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG3097 16-Dec-15 2015_12 "ENSDARG00000012013,ENSDARG00000045442(cpb1),ENSDARG00000037144(zgc:112493)" YHR132C(ECM14) WBGene00013895(ZC434.9) ENSXETG00000026124(cpb2) ENSMUSG00000039070(Cpa4) "ENSG00000128510(CPA4),ENSG00000165078(CPA6),ENSG00000163751(CPA3)" "viable,fertile" FBgn0014982 l(2)46Cc lethal (2) 46Cc http://flybase.net/reports/FBgn0014982.html gene "Group III, III" 16-Dec-15 2015_12 "lethal,male sterile,lethal - all die before end of larval stage,some die during larval stage" FBgn0002302 l(3)84Bb lethal (3) 84Bb http://flybase.net/reports/FBgn0002302.html gene l(3)84Ba 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,visible" FBgn0086672 snoRNA:Or-aca5 snoRNA:Or-aca5 http://flybase.net/reports/FBgn0086672.html "FBgn0065074, FBgn0082921, FBgn0053637" snoRNA_gene 0005730=nucleolus "chr2R:4607488..4607590, DmOr_aca5(SnoR227), CR33637, Or-aca5, Dm-227, DmOr_aca5, snoRNA:227, snoR227, DmOr_aca5 snoRNA" CR33637 16-Dec-15 2015_12 FBgn0020011 Fab-7 Fab-7 http://flybase.net/reports/FBgn0020011.html insulator "FAB-7, Fab7 PRE, Frontabdominal-7, Fab-7 PRE, Fab7" 16-Dec-15 2015_12 FBgn0063423 l(2)45Ar lethal (2) 45Ar http://flybase.net/reports/FBgn0063423.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002904 mus307 mutagen-sensitive 307 http://flybase.net/reports/FBgn0002904.html gene 16-Dec-15 2015_12 "radiation sensitive,chemical sensitive,recessive" FBgn0050007 CG30007 http://flybase.net/reports/FBgn0050007.html FBgn0033462 protein_coding_gene 0022008=neurogenesis CG12138 CG30007 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0025109 Bem46 Bem46 http://flybase.net/reports/FBgn0025109.html FBgn0031486 protein_coding_gene "unnamed, CG18642, c1.6" "IPR029058=Alpha/Beta hydrolase fold, IPR029059=Alpha/beta hydrolase fold-5" CG18642 16-Dec-15 2015_12 ENSDARG00000059209(abhd13) YNL320W() ENSXETG00000002652(ABHD13) ENSMUSG00000040396(Abhd13) ENSG00000139826(ABHD13) viable FBgn0266032 CR44797 http://flybase.net/reports/FBgn0266032.html non_protein_coding_gene CR44797 16-Dec-15 2015_12 FBgn0021993 l(2)k09601 lethal (2) k09601 http://flybase.net/reports/FBgn0021993.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086665 snoRNA:ë¬18S-1377a snoRNA:ë¬18S-1377a http://flybase.net/reports/FBgn0086665.html "FBgn0083051, FBgn0065067, FBgn0053750" snoRNA_gene 0005730=nucleolus "Psi 18S-1377a(SnoR328), chr3R:26033540..26033785, psi18S-1377a, snoR328, Psi18S-1377a, snoRNA:328, CR33750, Dm-328" CR33750 16-Dec-15 2015_12 FBgn0265302 CR44275 http://flybase.net/reports/FBgn0265302.html non_protein_coding_gene CR44275 16-Dec-15 2015_12 FBgn0035777 CG8563 http://flybase.net/reports/FBgn0035777.html protein_coding_gene "0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" 0006508=proteolysis "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG8563 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0022094 l(2)k07237 lethal (2) k07237 http://flybase.net/reports/FBgn0022094.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0037384 dgrn degringolade http://flybase.net/reports/FBgn0037384.html protein_coding_gene "0008270=zinc ion binding, 0001103=RNA polymerase II repressing transcription factor binding, 0061630=ubiquitin protein ligase activity, 0032183=SUMO binding" "0022008=neurogenesis, 0043393=regulation of protein binding, 0070201=regulation of establishment of protein localization, 0045893=positive regulation of transcription, DNA-templated, 0007530=sex determination, 0016567=protein ubiquitination, 0045995=regulation of embryonic development" "0005634=nucleus, 0005737=cytoplasm, 0033768=SUMO-targeted ubiquitin ligase complex" "CG10981, Degringolade" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR001841=Zinc finger, RING-type" CG10981 16-Dec-15 2015_12 ENSG00000063978(RNF4) "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,male,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" FBgn0031496 CG17258 http://flybase.net/reports/FBgn0031496.html protein_coding_gene CG17258 16-Dec-15 2015_12 ENSG00000163617(KIAA1407) "viable,visible" "chaeta,supernumerary" DRSC00495 E 0.346568903 1.389608345 2.617268929 1.009217771 0.240223121 -0.238024844 FBgn0069120 ms(3)Z2995 ms(3)Z2995 http://flybase.net/reports/FBgn0069120.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile testis FBgn0038401 CG5916 http://flybase.net/reports/FBgn0038401.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity IPR000195=Rab-GTPase-TBC domain CG5916 16-Dec-15 2015_12 "ENSDARG00000030269(grtp1b),ENSDARG00000029936(grtp1a)" "YOL112W(MSB4),YNL293W(MSB3)" WBGene00015410(tbc-6) ENSXETG00000001972(grtp1) ENSMUSG00000038515(Grtp1) ENSG00000139835(GRTP1) FBgn0001949 l(2)27Db lethal (2) 27Db http://flybase.net/reports/FBgn0001949.html gene "E, Complementation group E" 16-Dec-15 2015_12 lethal FBgn0032773 fon fondue http://flybase.net/reports/FBgn0032773.html protein_coding_gene "0007552=metamorphosis, 0042381=hemolymph coagulation" "0005576=extracellular region, 0005811=lipid particle" "Gpdhdue, CG15825, Fon, Fondue" CG15825 16-Dec-15 2015_12 "viable,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wound healing defective,immune response defective,partially lethal - majority die" "larva,pupa,pupal spiracle,hemolymph,pupal cuticle" FBgn0061097 l(3)S009826b lethal (3) S009826b http://flybase.net/reports/FBgn0061097.html gene 0098/26 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003979 Vm26Aa Vitelline membrane 26Aa http://flybase.net/reports/FBgn0003979.html protein_coding_gene 0008316=structural constituent of vitelline membrane "0048477=oogenesis, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" 0060388=vitelline envelope "Vm26A1, TU-2, VM26Aa, Vm26A.1, CG9048, sV17, VM26A.1, Vm26A" IPR013135=Vitelline membrane cysteine-rich domain CG9048 16-Dec-15 2015_12 " oogenesis stage | stage S8-10 , adult stage && oogenesis stage | stage S8-10 , oogenesis stage | stage S8-11 , adult stage && oogenesis stage " " oocyte

, follicle cell

" " oogenesis stage | stage S10-14 && adult stage | female , embryonic stage " " organism

, vitelline membrane

" viable FBgn0034307 CG10914 http://flybase.net/reports/FBgn0034307.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0042254=ribosome biogenesis 0005739=mitochondrion "IPR006073=GTP binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10914 16-Dec-15 2015_12 WBGene00013001(Y48E1B.2) ENSXETG00000005348(C4orf14) ENSMUSG00000036285(2610024G14Rik) ENSG00000084092(C4orf14) "partially lethal - majority die,some die during pupal stage" FBgn0010143 l(2)Sp18 lethal (2) Sp18 http://flybase.net/reports/FBgn0010143.html gene 16-Dec-15 2015_12 lethal FBgn0015612 Calpastatin Calpastatin http://flybase.net/reports/FBgn0015612.html gene 0004869=cysteine-type endopeptidase inhibitor activity 16-Dec-15 2015_12 FBgn0028329 l(1)G0299 lethal (1) G0299 http://flybase.net/reports/FBgn0028329.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,male,female" FBgn0023142 WppA White prepupal locus A http://flybase.net/reports/FBgn0023142.html gene 1 16-Dec-15 2015_12 FBgn0031992 CG8498 http://flybase.net/reports/FBgn0031992.html protein_coding_gene 0000062=fatty-acyl-CoA binding 0042049=cellular acyl-CoA homeostasis "IPR000582=Acyl-CoA-binding protein, ACBP, IPR022408=Acyl-CoA-binding protein, ACBP, conserved site, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle" CG8498 16-Dec-15 2015_12 "ENSDARG00000014856(acbd7),ENSDARG00000026369(zgc:77734)" ENSXETG00000027648(ACBD7) "ENSMUSG00000026644(Acbd7),ENSMUSG00000026385(Dbi)" "ENSG00000176244(ACBD7),ENSG00000155368(DBI)" viable FBgn0037503 CG14598 http://flybase.net/reports/FBgn0037503.html protein_coding_gene CG14598 16-Dec-15 2015_12 viable DRSC12541 I 1.535334074 1.534834829 0.679083342 0.097024236 -0.17339263 1.122427761 FBgn0065179 l(3)SH004 lethal (3) SH004 http://flybase.net/reports/FBgn0065179.html gene l(2)SH3 004 16-Dec-15 2015_12 "lethal,recessive" FBgn0028521 BG:DS03192.4 BG:DS03192.4 http://flybase.net/reports/FBgn0028521.html gene "DS03192.4, DS003192.4" 16-Dec-15 2015_12 FBgn0015536 ros rosario http://flybase.net/reports/FBgn0015536.html gene 0051299=centrosome separation fs(3)ros 16-Dec-15 2015_12 FBgn0259873 Su(Ste):CR42442 Su(Ste):CR42442 http://flybase.net/reports/FBgn0259873.html non_protein_coding_gene "RR41471, CR42442" CR42442 16-Dec-15 2015_12 FBgn0005616 msl-2 male-specific lethal 2 http://flybase.net/reports/FBgn0005616.html "FBgn0001317, FBgn0002852" protein_coding_gene "0003677=DNA binding, 0061630=ubiquitin protein ligase activity, 0003682=chromatin binding, 0008134=transcription factor binding, 0008270=zinc ion binding" "0009047=dosage compensation by hyperactivation of X chromosome, 0051865=protein autoubiquitination, 0016567=protein ubiquitination, 0007549=dosage compensation, 0016457=dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome" "0072487=MSL complex, 0005634=nucleus, 0005694=chromosome, 0046536=dosage compensation complex, 0016456=X chromosome located dosage compensation complex, transcription activating, 0000805=X chromosome, 0000228=nuclear chromosome" "male specific lethal 2, kmA, killer of males, male specific-lethal 2, MSL, male-specific-lethal-2, CG3241, km(2)A, male specifc lethal, MSL-2, MSL2, msl2, Msl-2, killer-of-males-A, Msl2, male-specific-lethal 2, msl, Msl 1-3" "IPR017907=Zinc finger, RING-type, conserved site, IPR001841=Zinc finger, RING-type" CG3241 16-Dec-15 2015_12 ENSMUSG00000066415 ENSG00000174579(MSL2) " larval stage | male , adult stage | female , adult stage | male , larval stage | female " " adult stage | male , larval stage | male " "lethal,male,female sterile,partially,developmental rate defective,female,viable,poor,heat sensitive,wild-type,visible,female limited,recessive,lethal - all die before end of larval stage,some die during larval stage" "eye,female" DRSC00829 I -0.194014437 1.848854694 -0.242461389 0.822805245 1.182746631 -0.325735184 FBgn0043594 E(roDOM)2051 E(roDOM)2051 http://flybase.net/reports/FBgn0043594.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0065889 l(2)SH0222 lethal (2) SH0222 http://flybase.net/reports/FBgn0065889.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267034 CR45478 http://flybase.net/reports/FBgn0267034.html non_protein_coding_gene CR45478 16-Dec-15 2015_12 FBgn0035604 Ir64a Ionotropic receptor 64a http://flybase.net/reports/FBgn0035604.html protein_coding_gene "0005230=extracellular ligand-gated ion channel activity, 0004984=olfactory receptor activity, 0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" "0050850=positive regulation of calcium-mediated signaling, 0042048=olfactory behavior, 0071311=cellular response to acetate, 0071468=cellular response to acidic pH, 0010157=response to chlorate, 0010034=response to acetate, 0050907=detection of chemical stimulus involved in sensory perception" "0071683=sensory dendrite, 0016021=integral component of membrane, 0032590=dendrite membrane" "ir64a, Ir64, ionotropic receptor 64a, CG10633, DmelIR64a, CT29782, IR64a" IPR001320=Ionotropic glutamate receptor CG10633 16-Dec-15 2015_12 "viable,smell perception defective,neurophysiology defective,recessive,auditory perception defective" "adult lateral horn type II neuron,antennal lobe glomerulus DP1m" FBgn0028175 l(3)S026409a lethal (3) S026409a http://flybase.net/reports/FBgn0028175.html gene "l(3)S026409, 0264/09" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0016059 Sema-1b Sema-1b http://flybase.net/reports/FBgn0016059.html "FBgn0023424, FBgn0028501" protein_coding_gene "0001700=embryonic development via the syncytial blastoderm, 0007411=axon guidance" "0005886=plasma membrane, 0005829=cytosol" "semaphorin, sema1b, D-semaIII, Sema 1b, semaphorin-I, Sema III, semiphorin, BcDNA:GH03186, semaphorin-like, Sema1b, CG6446, sema-III, semaphorin-III" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR001627=Sema domain, IPR016201=Plexin-like fold, IPR027231=Semaphorin" CG6446 16-Dec-15 2015_12 "ENSDARG00000011533(zgc:112012),ENSDARG00000002748(sema6d),ENSDARG00000018879,ENSDARG00000061976(LOC100148883)" ENSXETG00000022081(SEMA6B) "ENSMUSG00000038777(Sema6c),ENSMUSG00000001227(Sema6b),ENSMUSG00000019647(Sema6a),ENSMUSG00000027200(Sema6d)" "ENSG00000167680(SEMA6B),ENSG00000092421(SEMA6A),ENSG00000137872(SEMA6D),ENSG00000143434(SEMA6C)" " embryonic stage | stage 5-10 , embryonic stage && pupal stage , adult stage && oogenesis stage | stage S10 , embryonic stage | stage 2 , embryonic stage | stage 12-15 , adult stage && oogenesis stage | stage S2-8 " " mesectoderm

, nurse cell

,

ubiquitous , ectoderm

, ovariole

" neuroanatomy defective "filamentous actin,intersegmental nerve" FBgn0040514 CG17169 http://flybase.net/reports/FBgn0040514.html FBan0017169 protein_coding_gene CG17169 16-Dec-15 2015_12 FBgn0000533 ea easter http://flybase.net/reports/FBgn0000533.html protein_coding_gene "0008233=peptidase activity, 0008236=serine-type peptidase activity, 0004252=serine-type endopeptidase activity" "0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0008063=Toll signaling pathway, 0009950=dorsal/ventral axis specification, 0006508=proteolysis, 0006952=defense response, 0031638=zymogen activation" 0005576=extracellular region "CG4920, EA, SP24, Easter, c-SP24" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR006604=Disulphide knot CLIP, IPR001314=Peptidase S1A, chymotrypsin-type, IPR022700=Proteinase, regulatory CLIP domain, IPR001254=Serine proteases, trypsin domain" CG4920 16-Dec-15 2015_12 " oogenesis stage && adult stage | female , embryonic stage | early " ovary

"female fertile,wild-type,female sterile,dominant,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,viable,germline clone,non-rescuable maternal effect,heat sensitive" "embryonic/first instar larval cuticle,maternal effect,embryo,ventral,embryonic epidermis,head,extended germ band embryo,dorsal closure embryo,ventral furrow,denticle belt,cephalic furrow,dorsal fold,filzkorper,dorsal hair,embryonic head,heat sensitive,cephalopharyngeal skeleton" FBgn0067662 prage prage http://flybase.net/reports/FBgn0067662.html gene 0007343=egg activation prg 16-Dec-15 2015_12 FBgn0038525 CG14329 http://flybase.net/reports/FBgn0038525.html protein_coding_gene CG14329 16-Dec-15 2015_12 viable DRSC14808 I 0.098117955 1.8109032 -0.422408207 -1.219247385 -0.485741985 0.713217373 FBgn0261699 CR42735 http://flybase.net/reports/FBgn0261699.html non_protein_coding_gene "HDC01070, CG42735" CR42735 16-Dec-15 2015_12 FBgn0040649 CG15461 http://flybase.net/reports/FBgn0040649.html protein_coding_gene CG15461 16-Dec-15 2015_12 FBgn0069141 mcl(3)Z5468 mcl(3)Z5468 http://flybase.net/reports/FBgn0069141.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0002796 ms(1)4 male sterile (1) 4 http://flybase.net/reports/FBgn0002796.html gene 16-Dec-15 2015_12 "male sterile,female fertile,viable" "major mitochondrial derivative,spermatozoon" FBgn0041110 medo medo http://flybase.net/reports/FBgn0041110.html gene "0007254=JNK cascade, 0007391=dorsal closure" 16-Dec-15 2015_12 FBgn0027140 l(3)77Ea lethal (3) 77Ea http://flybase.net/reports/FBgn0027140.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0267631 CR45969 http://flybase.net/reports/FBgn0267631.html non_protein_coding_gene CR45969 16-Dec-15 2015_12 FBgn0259231 CCKLR-17D1 Cholecystokinin-like receptor at 17D1 http://flybase.net/reports/FBgn0259231.html "FBgn0030950, FBgn0046520, FBgn0046521, FBan0006857, FBgn0259197" protein_coding_gene "0004930=G-protein coupled receptor activity, 0015054=gastrin receptor activity, 0008188=neuropeptide receptor activity, 0004951=cholecystokinin receptor activity" "0033555=multicellular organismal response to stress, 0007186=G-protein coupled receptor signaling pathway, 0007204=positive regulation of cytosolic calcium ion concentration, 0007528=neuromuscular junction development, 0008344=adult locomotory behavior, 0007218=neuropeptide signaling pathway, 0008345=larval locomotory behavior" "0043025=neuronal cell body, 0016021=integral component of membrane, 0043195=terminal bouton, 0005887=integral component of plasma membrane" "anon-WO0170980.61, CG42301, unnamed, DSK-R2, cholecystokinin-like receptor, CCKLR-D1, anon-WO0170980.62, CCK-like receptor at 17D1, DskR-2, Dm CG6857, Cholecystokinin-like receptor, CCKLR, CG6857" "IPR009126=Cholecystokinin receptor, IPR000314=Gastrin receptor, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG42301 16-Dec-15 2015_12 ENSDARG00000052089(LOC569038) "WBGene00021439(ckr-2),WBGene00020712(ckr-1)" ENSXETG00000000911(CCKAR) "ENSMUSG00000030898(Cckbr),ENSMUSG00000029193(Cckar)" "ENSG00000163394(CCKAR),ENSG00000110148(CCKBR)" "neuroanatomy defective,viable,lethal" "embryonic/larval neuromuscular junction,NMJ bouton,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage" FBgn0036014 CG3222 http://flybase.net/reports/FBgn0036014.html FBgn0045268 protein_coding_gene "bs17c12.y1, NEST:bs17c12" IPR003409=MORN motif CG3222 16-Dec-15 2015_12 ENSDARG00000033610(morn5) ENSXETG00000016326(TEgg084k12.1) ENSMUSG00000026894(Morn5) ENSG00000185681(MORN5) viable FBgn0046637 anon-38D.8 anon-38D.8 http://flybase.net/reports/FBgn0046637.html gene 38D.8 16-Dec-15 2015_12 FBgn0260265 GSd440 http://flybase.net/reports/FBgn0260265.html gene 16-Dec-15 2015_12 lethal FBgn0084001 CG41434 http://flybase.net/reports/FBgn0084001.html FBan0041434 protein_coding_gene lincRNA.226 CG41434 16-Dec-15 2015_12 FBgn0005732 l(1)TK214 lethal (1) TK214 http://flybase.net/reports/FBgn0005732.html gene l214 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0267444 Su(Ste):CR45794 Supressor of Stellate:CR45794 http://flybase.net/reports/FBgn0267444.html non_protein_coding_gene CR45794 CR45794 16-Dec-15 2015_12 FBgn0065768 l(2)SH0470 lethal (2) SH0470 http://flybase.net/reports/FBgn0065768.html gene l(2)SH2 0470 16-Dec-15 2015_12 "lethal,recessive" FBgn0031957 TwdlE TweedleE http://flybase.net/reports/FBgn0031957.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle 0040003=chitin-based cuticle development 0005578=proteinaceous extracellular matrix CG14534 IPR004145=Domain of unknown function DUF243 CG14534 16-Dec-15 2015_12 "visible,partially lethal - majority die" pupa FBgn0265907 CR44696 http://flybase.net/reports/FBgn0265907.html non_protein_coding_gene CR44696 16-Dec-15 2015_12 FBgn0259450 EP-572 http://flybase.net/reports/FBgn0259450.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0000484 double double http://flybase.net/reports/FBgn0000484.html gene 16-Dec-15 2015_12 "visible,viable,reduced" "postvertical bristle,wing" FBgn0002564 Lsp1ë_ Larval serum protein 1 ë_ http://flybase.net/reports/FBgn0002564.html protein_coding_gene 0045735=nutrient reservoir activity "0005576=extracellular region, 0005811=lipid particle, 0005616=larval serum protein complex" "LSP-1 gamma, Lsp1, Lsp1gamma, LSP 1, Larval serum protein 1 gamma, DmeLSP1g, Lsp1gama, Lsp1[gamma], Lsp-1gamma, LSP1, Larval serum protein 1[gamma], Lsp1-gamma, Larval serum protein 1gamma, LSP-1gamma, CG6821" "IPR008922=Uncharacterised domain, di-copper centre, IPR013788=Hemocyanin/hexamerin, IPR005203=Hemocyanin, C-terminal, IPR005204=Hemocyanin, N-terminal, IPR000896=Hemocyanin/hexamerin middle domain, IPR014756=Immunoglobulin E-set" CG6821 16-Dec-15 2015_12 " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

larval stage | second instar -- larval stage | third instar embryonic/larval fat body

"viable,fertile" egg FBgn0001279 Jag Jagged http://flybase.net/reports/FBgn0001279.html gene 16-Dec-15 2015_12 "visible,dominant,recessive" "wing,eye" FBgn0264345 CR43801 http://flybase.net/reports/FBgn0264345.html non_protein_coding_gene lincRNA.56 CR43801 16-Dec-15 2015_12 FBgn0259561 B2014 http://flybase.net/reports/FBgn0259561.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment" FBgn0034629 Acox57D-d acyl-Coenzyme A oxidase at 57D distal http://flybase.net/reports/FBgn0034629.html "FBgn0024255, FBgn0026310" protein_coding_gene "0003995=acyl-CoA dehydrogenase activity, 0003997=acyl-CoA oxidase activity, 0016401=palmitoyl-CoA oxidase activity, 0050660=flavin adenine dinucleotide binding" 0006635=fatty acid beta-oxidation 0005777=peroxisome "acox, Acyl-coenzyme A oxidase, CG9709, D-acox, Acox57Dd, acyl co-enzyme A oxidase" "IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR012258=Acyl-CoA oxidase, IPR002655=Acyl-CoA oxidase, C-terminal, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR029320=Acyl-coenzyme A oxidase, N-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal" CG9709 16-Dec-15 2015_12 ENSDARG00000014727(acox1) "WBGene00010336(F59F4.1),WBGene00009104(F25C8.1),WBGene00008564(F08A8.1),WBGene00008567(F08A8.4),WBGene00008566(F08A8.3),WBGene00008565(F08A8.2),WBGene00008167(C48B4.1)" "ENSXETG00000012601(acox1),ENSXETG00000023676(acox2)" ENSMUSG00000020777(Acox1) ENSG00000161533(ACOX1) viable FBgn0000813 fs(1)K163 female sterile (1) K163 http://flybase.net/reports/FBgn0000813.html gene 16-Dec-15 2015_12 "partially lethal - majority live,female sterile,recessive,lethal,rescuable maternal effect" egg FBgn0069308 X-40-2 X-40-2 http://flybase.net/reports/FBgn0069308.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0039973 CG12563 http://flybase.net/reports/FBgn0039973.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262656 Myc Myc http://flybase.net/reports/FBgn0262656.html "FBgn0000472, FBgn0028362, FBgn0066838, FBgn0028316, FBgn0040170" protein_coding_gene "0005515=protein binding, 0046983=protein dimerization activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0055088=lipid homeostasis, 0090062=regulation of trehalose metabolic process, 0050769=positive regulation of neurogenesis, 0045793=positive regulation of cell size, 0042981=regulation of apoptotic process, 0040018=positive regulation of multicellular organism growth, 0045927=positive regulation of growth, 0046620=regulation of organ growth, 0009880=embryonic pattern specification, 0035212=cell competition in a multicellular organism, 0006355=regulation of transcription, DNA-templated, 0051726=regulation of cell cycle, 0022008=neurogenesis, 0010506=regulation of autophagy, 0008283=cell proliferation, 0042594=response to starvation, 0045746=negative regulation of Notch signaling pathway, 0008361=regulation of cell size, 0042023=DNA endoreduplication, 0045893=positive regulation of transcription, DNA-templated, 0048477=oogenesis, 0048639=positive regulation of developmental growth, 0009792=embryo development ending in birth or egg hatching, 0044719=regulation of imaginal disc-derived wing size, 0045572=positive regulation of imaginal disc growth, 0030307=positive regulation of cell growth, 0090277=positive regulation of peptide hormone secretion, 0001558=regulation of cell growth" "0005634=nucleus, 0035363=histone locus body, 0043234=protein complex" "diminuitive, myc, dMyc, dmyc, l(1)G0139, dMYC, c-myc, DM, dMyc1, anon-WO03040301.171, dm/myc, DMYc, D-Myc, dm/dMyc, bHLHe57, Dmyc, c-Myc, c-MYC, CG10798, Dm, l(1)G0359, diminutive, l(1)G0354, Myc, MYC, lethal (1) G0359, dm, dmyc1, EG:BACN5I9.1, lethal (1) G0354, d-myc" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG10798 16-Dec-15 2015_12 "ENSDARG00000006837(mycn),ENSDARG00000045695(myca),ENSDARG00000007241(mycb),ENSDARG00000034956(mycl1b),ENSDARG00000006003(mycl1a)" "ENSMUSG00000022346(Myc),ENSMUSG00000037169(Mycn),ENSMUSG00000044597(Mycs),ENSMUSG00000028654(Mycl1)" "ENSG00000136997(MYC),ENSG00000134323(MYCN),ENSG00000116990(MYCL1)" " oogenesis stage , embryonic stage | early , embryonic stage | extended germ band , embryonic stage -- adult stage , embryonic stage | stage >8 " " organism | anterior & posterior

, anterior midgut proper primordium

, posterior midgut proper primordium

, mesoderm | presumptive

" FBgn0014017 Re Rough eye http://flybase.net/reports/FBgn0014017.html gene 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" eye FBgn0266584 Gli::spi http://flybase.net/reports/FBgn0266584.html engineered_fusion_gene 16-Dec-15 2015_12 "photoreceptor,ectopic,somatic clone,eye disc,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7" FBgn0065330 l(2)SH1889 lethal (2) SH1889 http://flybase.net/reports/FBgn0065330.html gene l(2)SH2 1889 16-Dec-15 2015_12 "lethal,recessive" FBgn0022205 l(2)k04308 lethal (2) k04308 http://flybase.net/reports/FBgn0022205.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0051282 tRNA:CR31282 transfer RNA:CR31282 http://flybase.net/reports/FBgn0051282.html FBgn0060048 tRNA_gene 0033437=ACU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31282, tRNA[[Thr]], AE002708.trna8-ThrAGT, chr3R.trna14-ThrAGT, tRNA:T:AGT:AE002708-a" CR31282 16-Dec-15 2015_12 FBgn0024943 PIP82 PIP82 http://flybase.net/reports/FBgn0024943.html protein_coding_gene 0071482=cellular response to light stimulus CG11219 CG11219 16-Dec-15 2015_12 photoreceptor cell

viable FBgn0045961 Stalker\ORF2 ORF2 http://flybase.net/reports/FBgn0045961.html transposable_element_gene 16-Dec-15 2015_12 FBgn0060922 l(3)S042239 lethal (3) S042239 http://flybase.net/reports/FBgn0060922.html gene 0422/39 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031571 bark bark beetle http://flybase.net/reports/FBgn0031571.html protein_coding_gene "0005044=scavenger receptor activity, 0030246=carbohydrate binding" "0045217=cell-cell junction maintenance, 0034976=response to endoplasmic reticulum stress, 0090557=establishment of endothelial intestinal barrier, 0035002=liquid clearance, open tracheal system, 0035159=regulation of tube length, open tracheal system" "0016020=membrane, 0005918=septate junction, 0061689=tricellular tight junction, 0005912=adherens junction" "CG3921, anakonda, aka" "IPR001304=C-type lectin, IPR000859=CUB domain, IPR001190=SRCR domain, IPR012334=Pectin lyase fold, IPR011050=Pectin lyase fold/virulence factor, IPR016187=C-type lectin fold, IPR017448=SRCR-like domain, IPR016186=C-type lectin-like, IPR006626=Parallel beta-helix repeat" CG3921 16-Dec-15 2015_12 WBGene00007372(C06B8.7) "lethal,recessive" FBgn0267366 mil milkah http://flybase.net/reports/FBgn0267366.html "FBgn0066342, FBgn0039553" protein_coding_gene 0042393=histone binding "0008355=olfactory learning, 0006334=nucleosome assembly, 0007611=learning or memory, 0007613=memory, 0008049=male courtship behavior, 0007283=spermatogenesis" "0016006=Nebenkern, 0005634=nucleus, 0005829=cytosol" "hanabi, milkah-1, CG5017, milkah, Milkah" IPR002164=Nucleosome assembly protein (NAP) CG5017 16-Dec-15 2015_12 FBgn0029799 CG15772 http://flybase.net/reports/FBgn0029799.html protein_coding_gene 0005198=structural molecule activity 0019028=viral capsid "IPR001337=Tobacco mosaic virus-like, coat protein" CG15772 16-Dec-15 2015_12 "viable,fertile,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000037 mAChR-A "muscarinic Acetylcholine Receptor, A-type" http://flybase.net/reports/FBgn0000037.html protein_coding_gene "0016907=G-protein coupled acetylcholine receptor activity, 0008227=G-protein coupled amine receptor activity" "0007200=phospholipase C-activating G-protein coupled receptor signaling pathway, 0007213=G-protein coupled acetylcholine receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "muscarinic receptor, CG4356, mAChR, mAChR-1, mAChR A, Dm1, mAcR, muscarinic Acetylcholine Receptor, mAcR-60C, muscarinic Acetylcholine Receptor 60C, DM1, A-type mAChR, AcrC, Dm-mAChR-A, Acr60C, mAcR60C, Muscarinic acetylcholine Receptor 60C" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR000995=Muscarinic acetylcholine receptor family, IPR017452=GPCR, rhodopsin-like, 7TM" CG4356 16-Dec-15 2015_12 "ENSDARG00000004026(chrm5a),ENSDARG00000069598(chrm5b),ENSDARG00000037292(LOC792708)" WBGene00001519(gar-3) "ENSXETG00000017868(CHRM5),ENSXETG00000016229(CHRM3)" "ENSMUSG00000074939(Chrm5),ENSMUSG00000046159(Chrm3),ENSMUSG00000032773(Chrm1)" "ENSG00000133019(CHRM3),ENSG00000184984(CHRM5),ENSG00000168539(CHRM1)" "viable,visible" mesothoracic tergum DRSC04702 IEK -1.892221833 -3.827775328 -3.300800693 -1.655518805 1.501080088 0.579795602 FBgn0005225 l(3)PL lethal Payne Left http://flybase.net/reports/FBgn0005225.html gene l (3) Payne Left 16-Dec-15 2015_12 lethal FBgn0060378 l(3)S135305 lethal (3) S135305 http://flybase.net/reports/FBgn0060378.html gene 1353/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0039149 CG18428 http://flybase.net/reports/FBgn0039149.html protein_coding_gene "IPR019532=Nuclear RNA-splicing-associated protein, SR-25" CG18428 16-Dec-15 2015_12 ENSDARG00000051971(LOC100331837) ENSMUSG00000029404(Arl6ip4) viable FBgn0011588 eightless eightless http://flybase.net/reports/FBgn0011588.html gene 0048477=oogenesis 16-Dec-15 2015_12 FBgn0039188 Golgin84 Golgin-84 ortholog (H. sapiens) http://flybase.net/reports/FBgn0039188.html protein_coding_gene "0042803=protein homodimerization activity, 0017137=Rab GTPase binding" "0048193=Golgi vesicle transport, 0007030=Golgi organization" "0005794=Golgi apparatus, 0031985=Golgi cisterna" "Golgin84, CG17785" IPR019177=Golgin subfamily A member 5 CG17785 16-Dec-15 2015_12 ENSDARG00000039279(golga5) ENSXETG00000010301(GOLGA5) ENSMUSG00000021192(Golga5) ENSG00000066455(GOLGA5) viable FBgn0266070 CR44823 http://flybase.net/reports/FBgn0266070.html non_protein_coding_gene CR44823 16-Dec-15 2015_12 FBgn0001324 kto kohtalo http://flybase.net/reports/FBgn0001324.html FBgn0036912 protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0005515=protein binding" "0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007406=negative regulation of neuroblast proliferation, 0006357=regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development, 0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0030177=positive regulation of Wnt signaling pathway, 0036011=imaginal disc-derived leg segmentation, 0022416=chaeta development, 0045498=sex comb development" "0005700=polytene chromosome, 0070847=core mediator complex, 0016592=mediator complex, 0005634=nucleus" "dTRAP230, CG8491, siren1, Trap230, med12, Mediator complex subunit 12, Kto/Med12, Srb8/KTO/TRAP230, med12/kto, psg14, Brm @ Kto, Kto, Med12, khotalo, dTrap230, MED12, SRB8, l(3)76BDc" "IPR019035=Mediator complex, subunit Med12, IPR021990=Mediator complex, subunit Med12, LCEWAV-domain" CG8491 16-Dec-15 2015_12 ENSDARG00000056800(med12) WBGene00001081(dpy-22) "ENSMUSG00000056476,ENSMUSG00000079487(Med12)" "ENSG00000144893(MED12L),ENSG00000184634(MED12)" larval stage organism | ubiquitous

"lethal,recessive,visible,partially,somatic clone,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,leg,eye disc,photoreceptor cell,antennal disc,heart primordium,wing disc,somatic clone,somatic clone - Minute background,sex comb tooth,prothoracic tarsal segment,eye,mesothoracic bristle,wing margin,wing,trichogen cell,mesothoracic tergum" DRSC10983 IEK 0.766543982 1.513557464 0.593589389 1.933794038 1.632139166 1.232516512 FBgn0029920 CR4575 http://flybase.net/reports/FBgn0029920.html pseudogene_attribute "DM21, CG4575" CR4575 16-Dec-15 2015_12 FBgn0262569 CG43109 http://flybase.net/reports/FBgn0262569.html protein_coding_gene CG43109 16-Dec-15 2015_12 FBgn0053238 Ste:CG33238 Ste:CG33238 http://flybase.net/reports/FBgn0053238.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33238" "IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR000704=Casein kinase II, regulatory subunit" CG33238 16-Dec-15 2015_12 FBgn0261057 Sfp36F Seminal fluid protein 36F http://flybase.net/reports/FBgn0261057.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG42605 16-Dec-15 2015_12 FBgn0003569 supact suppressor activated http://flybase.net/reports/FBgn0003569.html gene 16-Dec-15 2015_12 "eye,female,macrochaeta" FBgn0000217 bre bright eye http://flybase.net/reports/FBgn0000217.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,male fertile,fertile,female,poor,eye color defective,female fertile,reduced" "wing,abdomen,pigment cell,adult abdomen" FBgn0083025 snoRNA:ë¬18S-640b snoRNA:ë¬18S-640b http://flybase.net/reports/FBgn0083025.html snoRNA_gene "CR34574, psi18s-640b" CR34574 16-Dec-15 2015_12 FBgn0065882 l(2)SH0232 lethal (2) SH0232 http://flybase.net/reports/FBgn0065882.html gene l(2)SH2 0232 16-Dec-15 2015_12 "lethal,recessive" FBgn0264880 CR44071 http://flybase.net/reports/FBgn0264880.html non_protein_coding_gene CR44071 16-Dec-15 2015_12 FBgn0067665 p70 p70 http://flybase.net/reports/FBgn0067665.html gene 16-Dec-15 2015_12 FBgn0051614 His-ë¬:CR31614 His-ë¬:CR31614 http://flybase.net/reports/FBgn0051614.html pseudogene_attribute CR31614 CR31614 16-Dec-15 2015_12 FBgn0065138 l(3)SH114 lethal (3) SH114 http://flybase.net/reports/FBgn0065138.html gene l(2)SH3 114 16-Dec-15 2015_12 "lethal,recessive" FBgn0052764 CR32764 http://flybase.net/reports/FBgn0052764.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0011281 Obp83a Odorant-binding protein 83a http://flybase.net/reports/FBgn0011281.html FBgn0010404 protein_coding_gene "0005549=odorant binding, 0005550=pheromone binding, 0008145=phenylalkylamine binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "pbprp-3, PBPRP3, CG11421, PB-PRP3, obp83a, Obp83a, Obp33a, Pheromone-binding protein Homolog 2, Pbprp3, DmelObp83a, pbprp3(OS-F), pbprp3, OS-F/PBP3, OS-F, PBPRP-3, 83a, Pheromone-binding protein-related protein 3, Os-F, PBP-H2, Olfactory-specific-F" IPR006170=Pheromone/general odorant binding protein CG11421 16-Dec-15 2015_12 adult stage " antennal segment 3

, sensillum trichodeum of antennal segment 3

, antennal segment 3 | anterior

" viable FBgn0030016 Or7a Odorant receptor 7a http://flybase.net/reports/FBgn0030016.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "CG10759, DOR30, DmOR7a, 7a, 7D.1" "IPR004117=Olfactory receptor, Drosophila" CG10759 16-Dec-15 2015_12 smell perception defective FBgn0032294 Vha16-5 Vacuolar H+ ATPase 16kD subunit 5 http://flybase.net/reports/FBgn0032294.html protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "vha16-5, Vacuolar H[+] ATPase subunit 16-5, CG6737" "IPR000245=V-ATPase proteolipid subunit, IPR002379=V-ATPase proteolipid subunit C-like domain, IPR011555=V-ATPase proteolipid subunit C, eukaryotic" CG6737 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum DRSC02986 E 0.074986612 0.70753882 1.839979567 -0.014668084 -0.143423252 -0.02190931 FBgn0259374 EP-644 http://flybase.net/reports/FBgn0259374.html gene 16-Dec-15 2015_12 visible wing vein FBgn0020775 vd vena decussata http://flybase.net/reports/FBgn0020775.html gene 16-Dec-15 2015_12 FBgn0044328 CG32052 http://flybase.net/reports/FBgn0044328.html "FBgn0036049, FBgn0052052" protein_coding_gene 0004767=sphingomyelin phosphodiesterase activity "aSMase, BEST:HL01355, Smase, CG8163" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like" CG32052 16-Dec-15 2015_12 "ENSDARG00000010130(LOC564392),ENSDARG00000053119(zgc:113352)" WBGene00014106(ZK856.5) "ENSXETG00000012883(SMPDL3B),ENSXETG00000023296(smpdl3a)" "ENSMUSG00000028885(Smpdl3b),ENSMUSG00000019872(Smpdl3a)" "ENSG00000130768(SMPDL3B),ENSG00000172594(SMPDL3A)" viable FBgn0000668 fliB flightless B http://flybase.net/reports/FBgn0000668.html gene 0007629=flight behavior 16-Dec-15 2015_12 "flightless,heat sensitive,jumping defective,flight defective" FBgn0024867 l(3)01619 lethal (3) 01619 http://flybase.net/reports/FBgn0024867.html gene 1619 16-Dec-15 2015_12 "lethal,recessive" FBgn0040000 CG15215 http://flybase.net/reports/FBgn0040000.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266174 pre-mod(mdg4)-L http://flybase.net/reports/FBgn0266174.html protein_coding_gene CG44880 CG44880 16-Dec-15 2015_12 FBgn0261726 EC497 http://flybase.net/reports/FBgn0261726.html gene 16-Dec-15 2015_12 "lethal - all die before end of first instar larval stage,some die during first instar larval stage" FBgn0011142 l(1)Q218 lethal (1) Q218 http://flybase.net/reports/FBgn0011142.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0259758 ms(3)Z1190 http://flybase.net/reports/FBgn0259758.html gene "0051276=chromosome organization, 0007283=spermatogenesis" "ms(3)150-16, 150-016" 16-Dec-15 2015_12 "male sterile,viable" Y chromosome loop FBgn0025771 l(3)89Ad lethal (3) 89Ad http://flybase.net/reports/FBgn0025771.html gene 16-Dec-15 2015_12 FBgn0005322 nmd no mitochondrial derivative http://flybase.net/reports/FBgn0005322.html "FBgn0010653, FBgn0013648, FBgn0025974, FBgn0032212" protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity" "0007286=spermatid development, 0048190=wing disc dorsal/ventral pattern formation" "0005783=endoplasmic reticulum, 0005741=mitochondrial outer membrane" "ms(2)4, CG5395, Msp1, ms(2)ry4, Msp, Nmd, clone 1.79, unnamed, l(2)08774, anon-EST:Liang-1.79, Mitochondrial sorting protein 1, DmCG5395" "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain" CG5395 16-Dec-15 2015_12 ENSDARG00000056609(atad1b) YGR028W(MSP1) WBGene00010557(mspn-1) ENSXETG00000009266(ATAD1) ENSMUSG00000013662(Atad1) ENSG00000138138(ATAD1) "male sterile,recessive,female fertile,lethal,visible,partially lethal - majority die,some die during pupal stage" "onion stage spermatid,Nebenkern derivative,spermatid axoneme,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,mesothoracic tergum" FBgn0037242 CG9855 http://flybase.net/reports/FBgn0037242.html FBan0009855 protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination "0005741=mitochondrial outer membrane, 0005789=endoplasmic reticulum membrane" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011016=Zinc finger, RING-CH-type" CG9855 16-Dec-15 2015_12 "ENSDARG00000032552(march5),ENSDARG00000028559(march5l)" ENSXETG00000012197(MARCH5) ENSMUSG00000023307(March5) ENSG00000198060(MARCH5) viable FBgn0260123 2L1281 http://flybase.net/reports/FBgn0260123.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval epidermis,somatic clone" FBgn0266719 Unc-13-4B Unc-13 ortholog 4B (C. elegans) http://flybase.net/reports/FBgn0266719.html "FBgn0085378, FBgn0082893, FBgn0039268, FBgn0054037, FBgn0042629" protein_coding_gene "0016082=synaptic vesicle priming, 0007269=neurotransmitter secretion" 0008021=synaptic vesicle "unc-13-4B, CG34349, dunc-13-4B, CG11819, unnamed, BP1013, CG34037" "IPR014770=Munc13 homology 1, IPR014772=Mammalian uncoordinated homology 13, domain 2, IPR000008=C2 domain" CG34349 16-Dec-15 2015_12 "ENSDARG00000061829(si:dkey-110c1.7),ENSDARG00000017391" FBgn0030847 CG12991 http://flybase.net/reports/FBgn0030847.html protein_coding_gene CG12991 16-Dec-15 2015_12 viable FBgn0086473 l(3)EY09182 http://flybase.net/reports/FBgn0086473.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069976 CG40473 http://flybase.net/reports/FBgn0069976.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019673 mor(1)6 mortality gene (1)6 http://flybase.net/reports/FBgn0019673.html gene 16-Dec-15 2015_12 short lived FBgn0030518 CG11134 http://flybase.net/reports/FBgn0030518.html protein_coding_gene 0046872=metal ion binding 0019509=L-methionine biosynthetic process from methylthioadenosine 0005737=cytoplasm "1, transcript 1" "IPR001303=Class II aldolase/adducin N-terminal, IPR027514=Methylthioribulose-1-phosphate dehydratase, eukaryotes, IPR017714=Methylthioribulose-1-phosphate dehydratase" CG11134 16-Dec-15 2015_12 ENSDARG00000003132(apip) YJR024C(MDE1) WBGene00013870(ZC373.5) ENSXETG00000007558(BC089643.1) ENSMUSG00000010911(Apip) ENSG00000149089(APIP) embryonic/larval hemocyte | third instar larval stage DRSC19384 E 0.859439463 1.2964004 1.86941592 -0.223484528 0.07425959 1.147245039 FBgn0044117 E(rst)C109 E(rst)C109 http://flybase.net/reports/FBgn0044117.html gene 0001745=compound eye morphogenesis C109 16-Dec-15 2015_12 viable FBgn0036550 CG17026 http://flybase.net/reports/FBgn0036550.html protein_coding_gene 0008934=inositol monophosphate 1-phosphatase activity "0046854=phosphatidylinositol phosphorylation, 0016311=dephosphorylation, 0046855=inositol phosphate dephosphorylation" 0005737=cytoplasm cg17026 "IPR020550=Inositol monophosphatase, conserved site, IPR020583=Inositol monophosphatase, metal-binding site, IPR020552=Inositol monophosphatase, Lithium-sensitive, IPR000760=Inositol monophosphatase" CG17026 16-Dec-15 2015_12 viable FBgn0029963 CG10920 http://flybase.net/reports/FBgn0029963.html protein_coding_gene 0022857=transmembrane transporter activity 0005739=mitochondrion "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG10920 16-Dec-15 2015_12 WBGene00018395(F43E2.7) viable DRSC17765 K 0.589942067 -0.00125173 0.81691895 0.224616099 1.469723823 2.111677332 FBgn0039428 CG14237 http://flybase.net/reports/FBgn0039428.html protein_coding_gene CG14237 16-Dec-15 2015_12 FBgn0266366 CR45014 http://flybase.net/reports/FBgn0266366.html non_protein_coding_gene CR45014 16-Dec-15 2015_12 FBgn0026239 gukh GUK-holder http://flybase.net/reports/FBgn0026239.html "FBgn0038668, FBgn0038669, FBgn0038670, FBgn0038671, FBgn0051043, FBgn0062172" protein_coding_gene 0005515=protein binding "0008104=protein localization, 0030036=actin cytoskeleton organization, 0007411=axon guidance" "0042734=presynaptic membrane, 0005856=cytoskeleton, 0043195=terminal bouton" "CG14287, CG5456, CG6003, GUKh, gukholder, GUKH, GukH, anon-WO0118547.205, GUKholder, GUK holder, GukHolder, CG14288, Gukh, CG31043" IPR028288=SCAR/WAVE family CG31043 16-Dec-15 2015_12 "ENSXETG00000001112(NHS),ENSXETG00000006237(NHSL1)" ENSMUSG00000059493(Nhs) "ENSG00000188158(NHS),ENSG00000135540(NHSL1)" "viable,neuroanatomy defective,somatic clone,lethal,recessive" FBgn0262095 CR42848 http://flybase.net/reports/FBgn0262095.html non_protein_coding_gene CG42848 CR42848 16-Dec-15 2015_12 FBgn0039077 CG17380 http://flybase.net/reports/FBgn0039077.html FBgn0047344 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity BcDNA:AT18288 "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG17380 16-Dec-15 2015_12 ENSDARG00000069736 viable FBgn0039473 CG17191 http://flybase.net/reports/FBgn0039473.html protein_coding_gene "0016298=lipase activity, 0008970=phosphatidylcholine 1-acylhydrolase activity" 0016042=lipid catabolic process "DmelL4, Triglyceride lipase" "IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family, IPR002334=Vespid venom allergen phospholipase A1, IPR029058=Alpha/Beta hydrolase fold" CG17191 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) FBgn0052229 CR32229 http://flybase.net/reports/FBgn0052229.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0039089 beat-IV beat-IV http://flybase.net/reports/FBgn0039089.html FBgn0039090 protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "beat IV, CG10152, CG13823, Beat-IV, beatIV" "IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG10152 16-Dec-15 2015_12 "oxidative stress response defective,partially lethal - majority die,some die during pupal stage" FBgn0061136 l(3)S001012 lethal (3) S001012 http://flybase.net/reports/FBgn0061136.html gene 12-Oct 16-Dec-15 2015_12 "lethal,recessive" FBgn0260969 CG42592 http://flybase.net/reports/FBgn0260969.html protein_coding_gene CG42592 16-Dec-15 2015_12 FBgn0001617 l(1)10Eb lethal (1) 10Eb http://flybase.net/reports/FBgn0001617.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065055 snoRNA:ë¬28S-2648 http://flybase.net/reports/FBgn0065055.html FBgn0053693 snoRNA_gene 0005730=nucleolus "CR33693, Dm-72, psi28s-2648, snoRNA:72, snoR72, psi28s-2648 snoRNA, Psi 28S-2648(SnoR72)" CR33693 16-Dec-15 2015_12 FBgn0032506 CG9395 http://flybase.net/reports/FBgn0032506.html protein_coding_gene IPR008166=Glycosyltransferase family 92 CG9395 16-Dec-15 2015_12 viable DRSC03218 I 1.388632043 1.592936079 1.415024982 0.43074705 -0.848257943 -0.210018955 FBgn0010192 tu-mwh tu-mwh http://flybase.net/reports/FBgn0010192.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval lymph gland FBgn0052206 CG32206 http://flybase.net/reports/FBgn0052206.html "FBgn0036864, FBgn0036865, FBgn0036866, FBgn0036867" protein_coding_gene "0017147=Wnt-protein binding, 0042813=Wnt-activated receptor activity" "0060070=canonical Wnt signaling pathway, 0044332=Wnt signaling pathway involved in dorsal/ventral axis specification, 0046331=lateral inhibition" "CG14091, CG9600, CG14092, CG14090" "IPR000859=CUB domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG32206 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0005737 l(1)TK226 lethal (1) TK226 http://flybase.net/reports/FBgn0005737.html gene l226 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0266033 CR44798 http://flybase.net/reports/FBgn0266033.html non_protein_coding_gene CR44798 16-Dec-15 2015_12 FBgn0000053 ade3 adenosine 3 http://flybase.net/reports/FBgn0000053.html "FBgn0051628, FBgn0063628" protein_coding_gene "0004641=phosphoribosylformylglycinamidine cyclo-ligase activity, 0005524=ATP binding, 0004644=phosphoribosylglycinamide formyltransferase activity, 0046872=metal ion binding, 0008168=methyltransferase activity, 0004637=phosphoribosylamine-glycine ligase activity" "0006189='de novo' IMP biosynthetic process, 0009113=purine nucleobase biosynthetic process" 0005829=cytosol "GART, Gart, Complementation group D, CG31628, 143062_at, l(2)27Da, D, Gart/ade3, ADE8, CG8761, gart, Ade3" "IPR010918=AIR synthase-related protein, C-terminal domain, IPR016188=PurM-like, N-terminal domain, IPR011761=ATP-grasp fold, IPR013816=ATP-grasp fold, subdomain 2, IPR016185=Pre-ATP-grasp domain, IPR004607=Phosphoribosylglycinamide formyltransferase, IPR020560=Phosphoribosylglycinamide synthetase, C-domain, IPR020562=Phosphoribosylglycinamide synthetase, N-terminal, IPR013815=ATP-grasp fold, subdomain 1, IPR020561=Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain, IPR001555=Phosphoribosylglycinamide formyltransferase, active site, IPR011054=Rudiment single hybrid motif, IPR002376=Formyl transferase, N-terminal, IPR000115=Phosphoribosylglycinamide synthetase, IPR020559=Phosphoribosylglycinamide synthetase, conserved site, IPR004733=Phosphoribosylformylglycinamidine cyclo-ligase" CG31628 16-Dec-15 2015_12 ENSDARG00000051855 "YGL234W(ADE5,7)" WBGene00018174(F38B6.4) ENSXETG00000000041() ENSMUSG00000022962(Gart) ENSG00000159131(GART) "auxotroph,recessive,lethal,visible,eye color defective,viable" "wing,wing vein,dorsal row,ventral row,trichome of the posterior wing margin,macrochaeta,tarsal segment,pigment cell" FBgn0017611 Gelatinase Gelatinase http://flybase.net/reports/FBgn0017611.html gene 0004222=metalloendopeptidase activity 0006508=proteolysis unnamed 16-Dec-15 2015_12 FBgn0027161 l(2)KC-E l(2)Karp and Cherbas E http://flybase.net/reports/FBgn0027161.html gene E 16-Dec-15 2015_12 "lethal,recessive" FBgn0267172 CR45612 http://flybase.net/reports/FBgn0267172.html non_protein_coding_gene CR45612 16-Dec-15 2015_12 FBgn0001080 Fuc ë± Fucosidase http://flybase.net/reports/FBgn0001080.html gene 0004560=alpha-L-fucosidase activity "fuc, alpha-FUC, CG6128, alpha-fucosidase, a-FUC" 16-Dec-15 2015_12 "electrophoretic variant,fertile,viable" FBgn0065646 l(2)SH0750 lethal (2) SH0750 http://flybase.net/reports/FBgn0065646.html gene l(2)SH2 0750 16-Dec-15 2015_12 "lethal,recessive" FBgn0038859 Obp93a Odorant-binding protein 93a http://flybase.net/reports/FBgn0038859.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG17284, DmelObp93a" CG17284 16-Dec-15 2015_12 viable FBgn0026633 mys::tor mys::tor http://flybase.net/reports/FBgn0026633.html engineered_fusion_gene Tor[D]-myospheroid 16-Dec-15 2015_12 visible "amnioserosa,dorsal ectoderm,wing" FBgn0067064 Nrt::wntD Nrt::wntD http://flybase.net/reports/FBgn0067064.html engineered_fusion_gene Nrt::Wnt8 16-Dec-15 2015_12 FBgn0044404 Scim23 Sensitized chromosome inheritance modifier 23 http://flybase.net/reports/FBgn0044404.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0025795 Su(var)502 Suppressor of variegation 502 http://flybase.net/reports/FBgn0025795.html gene Su-var(2)502 16-Dec-15 2015_12 FBgn0063779 s(3)4B s(3)4B http://flybase.net/reports/FBgn0063779.html gene unnamed 16-Dec-15 2015_12 "sterile,recessive" FBgn0065676 l(2)SH0675 lethal (2) SH0675 http://flybase.net/reports/FBgn0065676.html gene l(2)SH2 0675 16-Dec-15 2015_12 "lethal,recessive" FBgn0264641 dark-matter dark matter http://flybase.net/reports/FBgn0264641.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0039518 CG13978 http://flybase.net/reports/FBgn0039518.html protein_coding_gene 0016740=transferase activity 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane "IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR002591=Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase, IPR017852=GPI ethanolamine phosphate transferase 1, C-terminal, IPR007070=GPI ethanolamine phosphate transferase 1" CG13978 16-Dec-15 2015_12 viable FBgn0026739 anon-64Cb anon-64Cb http://flybase.net/reports/FBgn0026739.html gene gene c 16-Dec-15 2015_12 FBgn0036461 Zip71B Zinc/iron regulated transporter-related protein 71B http://flybase.net/reports/FBgn0036461.html protein_coding_gene 0046873=metal ion transmembrane transporter activity "0055085=transmembrane transport, 0030001=metal ion transport" 0016020=membrane "cg10006, CG10006, dZip71B" IPR003689=Zinc/iron permease CG10006 16-Dec-15 2015_12 YIL023C(YKE4) WBGene00021936(Y55F3BL.2) viable FBgn0004768 l(3)89Eg lethal (3) 89Eg http://flybase.net/reports/FBgn0004768.html gene 16-Dec-15 2015_12 lethal FBgn0264340 CG43796 http://flybase.net/reports/FBgn0264340.html protein_coding_gene CG43796 16-Dec-15 2015_12 FBgn0047299 CG31535 http://flybase.net/reports/FBgn0047299.html FBgn0051535 protein_coding_gene BcDNA:GH26355 16-Dec-15 2015_12 FBgn0034351 CG5190 http://flybase.net/reports/FBgn0034351.html protein_coding_gene 0005739=mitochondrion "IPR025812=Mitochondrial ribonuclease P, tRNA methyltransferase protein 1, IPR016009=tRNA methyltransferase TRMD/TRM10-type domain, IPR007356=tRNA (guanine-N1-)-methyltransferase, eukaryotic, IPR028564=tRNA methyltransferase TRM10-type domain" CG5190 16-Dec-15 2015_12 ENSDARG00000060176 WBGene00018513(F46F11.10) ENSMUSG00000044763(Rg9mtd1) ENSG00000174173(RG9MTD1) "viable,visible" trichogen cell FBgn0060361 l(3)S139213 lethal (3) S139213 http://flybase.net/reports/FBgn0060361.html gene 1392/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003025 ove over-etherised http://flybase.net/reports/FBgn0003025.html gene overetherized 16-Dec-15 2015_12 uncoordinated FBgn0004908 Arl2 ADP ribosylation factor-like 2 http://flybase.net/reports/FBgn0004908.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0022008=neurogenesis, 0016197=endosomal transport, 0048488=synaptic vesicle endocytosis, 0007264=small GTPase mediated signal transduction, 0006471=protein ADP-ribosylation, 0007269=neurotransmitter secretion" 0005622=intracellular "Arf84F, Q06849, CG7435, Arf84D, Arf, unnamed, ADP ribosylation factor 84F, arl2, Dm Arf84F, Arl2, arflike-2, ARL2, Arl84F, CG 7435" "IPR024156=Small GTPase superfamily, ARF type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR006689=Small GTPase superfamily, ARF/SAR type" CG7435 16-Dec-15 2015_12 "ENSDARG00000069490,ENSDARG00000069496(zgc:103658)" WBGene00001358(evl-20) ENSXETG00000001661(arl2) ENSMUSG00000024944(Arl2) ENSG00000213465(ARL2) embryonic stage -- adult stage "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0026592 Fie Fire exit http://flybase.net/reports/FBgn0026592.html FBgn0035467 protein_coding_gene 0016021=integral component of membrane "HL04053, CG1079, BEST:HL04053" CG1079 16-Dec-15 2015_12 "viable,partially lethal - majority die,visible,wild-type,fertile" "tarsal segment,trichome,eye" FBgn0266042 CR44807 http://flybase.net/reports/FBgn0266042.html non_protein_coding_gene CR44807 16-Dec-15 2015_12 FBgn0028252 l(3)87Ce lethal (3) 87Ce http://flybase.net/reports/FBgn0028252.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032198 eEF1ë« eEF1ë« http://flybase.net/reports/FBgn0032198.html protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0003746=translation elongation factor activity" 0006414=translational elongation "0005875=microtubule associated complex, 0005853=eukaryotic translation elongation factor 1 complex" "eukaryotic translation elongation factor 1delta, eEf1delta, eEF1delta, CG4912, eEF1d" "IPR001326=Translation elongation factor EF1B, beta/delta chains, conserved site, IPR018940=Elongation factor 1 beta central acidic region, eukaryote, IPR014038=Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange, IPR014717=Translation elongation factor EF1B/ribosomal protein S6" CG4912 16-Dec-15 2015_12 ENSDARG00000008109(LOC100331034) ENSXETG00000004674(eef1d) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016034 mael maelstrom http://flybase.net/reports/FBgn0016034.html protein_coding_gene 0043565=sequence-specific DNA binding "0008104=protein localization, 0007314=oocyte anterior/posterior axis specification, 0048477=oogenesis, 0009950=dorsal/ventral axis specification, 0016325=oocyte microtubule cytoskeleton organization, 0010529=negative regulation of transposition, 0007283=spermatogenesis, 0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 0048600=oocyte fate commitment, 0045892=negative regulation of transcription, DNA-templated, 0019094=pole plasm mRNA localization, 0007010=cytoskeleton organization, 0007317=regulation of pole plasm oskar mRNA localization, 0046843=dorsal appendage formation, 0008298=intracellular mRNA localization, 0031023=microtubule organizing center organization" "0005634=nucleus, 0005737=cytoplasm, 0043186=P granule" "MAEL, Maelstrom, Mael, CG11254, mae1" "IPR024970=Maelstrom domain, IPR009071=High mobility group box domain" CG11254 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage S1-8 , adult stage | female && oogenesis stage " " nurse cell

, germarium && germline cell

" "female sterile,male sterile,sterile,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,female semi-sterile" "dorsal appendage,germline clone,maternal effect,male germline cell,male germline cyst,spermatocyte ring canal,male germline stem cell,ectopic,female germline stem cell,supernumerary,cystoblast,germarium region 3,germline cell,egg chamber,ovary,karyosome,oocyte & microtubule,oocyte & centriole79E-F),oocyte & microtubule organizing center79E-F),chorion | germline clone,oocyte,follicle cell,microtubule & oocyte" FBgn0004092 l(2)60Cd lethal (2) 60Cd http://flybase.net/reports/FBgn0004092.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0032088 CG13102 http://flybase.net/reports/FBgn0032088.html FBgn0062998 protein_coding_gene BcDNA:RE57454 CG13102 16-Dec-15 2015_12 viable FBgn0016889 l(2)39DEn lethal (2) 39DEn http://flybase.net/reports/FBgn0016889.html gene L110 16-Dec-15 2015_12 lethal FBgn0002603 M(2)53 Minute (2) 53 http://flybase.net/reports/FBgn0002603.html gene "M(2)S-7, M(2)S7, M(2)53-1, M(2R)S7, M(2)53C" 16-Dec-15 2015_12 "developmental rate defective,dominant,visible,Minute,small body" macrochaeta FBgn0033428 Updo Updo http://flybase.net/reports/FBgn0033428.html protein_coding_gene 0004853=uroporphyrinogen decarboxylase activity "0006779=porphyrin-containing compound biosynthetic process, 0006783=heme biosynthetic process" 0005737=cytoplasm CG1818 "IPR006361=Uroporphyrinogen decarboxylase HemE, IPR000257=Uroporphyrinogen decarboxylase (URO-D)" CG1818 16-Dec-15 2015_12 ENSDARG00000006818(urod) YDR047W(HEM12) ENSXETG00000003506(urod) ENSMUSG00000028684(Urod) ENSG00000126088(UROD) DRSC30007 K -0.858619708 -0.28628326 -0.014652526 -0.062674511 1.553191606 2.34894202 FBgn0033808 CG4627 http://flybase.net/reports/FBgn0033808.html protein_coding_gene IPR026571=Transmembrane protein 186 CG4627 16-Dec-15 2015_12 ENSMUSG00000043140(Tmem186) ENSG00000184857(TMEM186) "partially lethal - majority die,some die during pupal stage" FBgn0063392 snoRNA:U14:30Ea snoRNA:U14:30Ea http://flybase.net/reports/FBgn0063392.html snoRNA_gene 0030556=rRNA modification guide activity 0005730=nucleolus "CR32875, U14:30Ea, chr2L:9894175..9894283, U14snoRNA, snoRNA:U14:a, DmU14a(U14), Dm-396" CR32875 16-Dec-15 2015_12 FBgn0053384 5SrRNA:CR33384 5SrRNA:CR33384 http://flybase.net/reports/FBgn0053384.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33384 CR33384 16-Dec-15 2015_12 FBgn0020825 l(3)98Da lethal (3) 98Da http://flybase.net/reports/FBgn0020825.html gene "M313, l(3)M3-13, l(3)98D-Ea" 16-Dec-15 2015_12 "lethal,recessive" FBgn0065163 l(3)SH039 lethal (3) SH039 http://flybase.net/reports/FBgn0065163.html gene l(2)SH3 039 16-Dec-15 2015_12 "lethal,recessive" FBgn0004025 wt welt http://flybase.net/reports/FBgn0004025.html gene 16-Dec-15 2015_12 visible "eye,macrochaeta,postvertical bristle,abdomen,wing,eye disc,wing disc" FBgn0052762 CG32762 http://flybase.net/reports/FBgn0052762.html protein_coding_gene CG32762 16-Dec-15 2015_12 DRSC18298 I 1.782959867 -0.168214914 0.760168683 0.330907505 -0.188345434 -0.276319349 FBgn0025513 fs(3)82EFc fs(3)82EFc http://flybase.net/reports/FBgn0025513.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0061114 l(3)S005912 lethal (3) S005912 http://flybase.net/reports/FBgn0061114.html gene 0059/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0067058 P61 P61 http://flybase.net/reports/FBgn0067058.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0024756 EC91 EC91 http://flybase.net/reports/FBgn0024756.html gene 16-Dec-15 2015_12 "enhancer of variegation,female,non-enhancer of variegation,male" FBgn0266750 CR45223 http://flybase.net/reports/FBgn0266750.html non_protein_coding_gene CR45223 16-Dec-15 2015_12 FBgn0052073 CG32073 http://flybase.net/reports/FBgn0052073.html protein_coding_gene CG32073 16-Dec-15 2015_12 FBgn0011211 blw bellwether http://flybase.net/reports/FBgn0011211.html "FBgn0010487, FBgn0010561, FBgn0011298, FBgn0022274" protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism, 0046961=proton-transporting ATPase activity, rotational mechanism, 0005524=ATP binding" "0006909=phagocytosis, 1902769=regulation of choline O-acetyltransferase activity, 0019915=lipid storage, 0022900=electron transport chain, 0015991=ATP hydrolysis coupled proton transport, 0040007=growth, 0015992=proton transport, 0015986=ATP synthesis coupled proton transport, 0007286=spermatid development" "0005811=lipid particle, 0005739=mitochondrion, 0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), 0005875=microtubule associated complex" "ATP synthase, mitochondrial ATPase complex V-subunit alpha, l(2)03972, mitochondrial ATP synthase alpha subunit, Blw, alpha subunit of the mitochondrial F[[1]]F[[0]] ATPase, Complex Valpha, l(2)k00212, colibri, ATPsynalpha, alpha-subunit of ATP synthase, ATP synthase Alpha chain, ATP synthase, alpha subunit, Bellwether, ATP synthase alpha chain, Complex V alpha, ATPA, CG3612, l(2)59ABa, Mitochondrial ATP synthase subunit B, ms(2)01504, ATP synthetase alpha chain, alpha subunit of ATP synthase, Bellweather, ATP SYNTHASE ALPHA, F0/F1 ATP synthase Alpha, CValpha, ATP synthase subunits alpha, BELLWETHER, mitochondrial ATP synthase subunit alpha of complex V, l(2)01410, ATP synthase subunit alpha, ms(2)Pry58F, ATP synthase alpha subunit of complex V, ATP syn-alpha, alpha-ATP synthase, COMPLEX V: alpha chain, ATPA_DROME, ATP synthase alpha, CxV, ATP5a, A2(2nd)27, ATP synthase, subunit alpha, ATPsyn-alpha, complex Valpha subunit, C-V-alpha" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR023366=ATP synthase subunit alpha-like domain, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain, IPR005294=ATPase, F1 complex, alpha subunit, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal" CG3612 16-Dec-15 2015_12 ENSDARG00000010149(atp5a1) YBL099W(ATP1) WBGene00010419(H28O16.1) ENSXETG00000002315() ENSMUSG00000025428(Atp5a1) ENSG00000152234(ATP5A1) larval stage | third instar dorsal mesothoracic disc

"male sterile,recessive,viable,fertile,lethal,mitotic cell cycle defective,cell autonomous,decreased cell size,somatic clone,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,visible" "wing disc,cell autonomous,somatic clone,mesothoracic tergum" DRSC04675 K -0.410897119 0.230155598 -1.369506692 -0.017553756 1.761256119 2.056332329 FBgn0011028 l(3)s2500 lethal (3) s2500 http://flybase.net/reports/FBgn0011028.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031099 CG17065 http://flybase.net/reports/FBgn0031099.html protein_coding_gene 0008448=N-acetylglucosamine-6-phosphate deacetylase activity 0006044=N-acetylglucosamine metabolic process "IPR006680=Amidohydrolase-related, IPR011059=Metal-dependent hydrolase, composite domain, IPR003764=N-acetylglucosamine-6-phosphate deacetylase" CG17065 16-Dec-15 2015_12 ENSDARG00000021293 WBGene00010308(F59B2.3) ENSXETG00000020279(AMDHD2) ENSMUSG00000036820(Amdhd2) ENSG00000162066(AMDHD2) "viable,fertile,partially lethal - majority die" FBgn0024258 acd(2)5N18 auditory courtship defective 5N18 http://flybase.net/reports/FBgn0024258.html gene "0031223=auditory behavior, 0008049=male courtship behavior, 0007628=adult walking behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective,smell perception defective" adult brain FBgn0266143 CR44849 http://flybase.net/reports/FBgn0266143.html non_protein_coding_gene CR44849 16-Dec-15 2015_12 FBgn0036065 CG14161 http://flybase.net/reports/FBgn0036065.html protein_coding_gene 16-Dec-15 2015_12 FBgn0051072 Lerp lysosomal enzyme receptor protein http://flybase.net/reports/FBgn0051072.html "FBgn0039455, FBgn0039456, FBgn0039457, FBgn0039458, FBgn0062050" protein_coding_gene "0005515=protein binding, 0004872=receptor activity, 0005215=transporter activity" "0007041=lysosomal transport, 0006892=post-Golgi vesicle-mediated transport" "0016021=integral component of membrane, 0005802=trans-Golgi network, 0005737=cytoplasm, 0030136=clathrin-coated vesicle, 0048471=perinuclear region of cytoplasm" "CG14256, CG6390, CG14255, anon-WO0118547.383, Lysosomal enzyme receptor protein, LERP, CG31072, CG6396" "IPR009011=Mannose-6-phosphate receptor binding domain, IPR000479=Cation-independent mannose-6-phosphate receptor" CG31072 16-Dec-15 2015_12 "viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0001845 l(1)ts2864 lethal (1) ts2864 http://flybase.net/reports/FBgn0001845.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0063403 l(3)CG4 lethal (3) CG4 http://flybase.net/reports/FBgn0063403.html gene Complementation Group 4 16-Dec-15 2015_12 "lethal,recessive" FBgn0011049 l(1)Q2 lethal (1) Q2 http://flybase.net/reports/FBgn0011049.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0033856 CG13334 http://flybase.net/reports/FBgn0033856.html FBgn0045170 protein_coding_gene 0004459=L-lactate dehydrogenase activity "0005975=carbohydrate metabolic process, 0055114=oxidation-reduction process, 0019752=carboxylic acid metabolic process" NEST:bs27e02 "IPR015955=Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR001236=Lactate/malate dehydrogenase, N-terminal, IPR022383=Lactate/malate dehydrogenase, C-terminal, IPR016040=NAD(P)-binding domain, IPR001557=L-lactate/malate dehydrogenase" CG13334 16-Dec-15 2015_12 viable FBgn0037456 CG1138 http://flybase.net/reports/FBgn0037456.html protein_coding_gene CG1138 16-Dec-15 2015_12 viable FBgn0267219 CR45659 http://flybase.net/reports/FBgn0267219.html non_protein_coding_gene lincRNA.655 CR45659 16-Dec-15 2015_12 FBgn0031813 CG9527 http://flybase.net/reports/FBgn0031813.html protein_coding_gene "0003997=acyl-CoA oxidase activity, 0003995=acyl-CoA dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" "0006909=phagocytosis, 0006635=fatty acid beta-oxidation" 0005777=peroxisome "long chain acyl-CoA-dehydrogenase, LCAD" "IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR012258=Acyl-CoA oxidase, IPR002655=Acyl-CoA oxidase, C-terminal, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain" CG9527 16-Dec-15 2015_12 ENSDARG00000038865(acox3) YGL205W(POX1) WBGene00019060(F58F9.7) ENSMUSG00000029098(Acox3) ENSG00000087008(ACOX3) viable FBgn0035409 CG14963 http://flybase.net/reports/FBgn0035409.html protein_coding_gene IPR010629=Insect allergen-related CG14963 16-Dec-15 2015_12 viable FBgn0032656 CG5674 http://flybase.net/reports/FBgn0032656.html protein_coding_gene 0046331=lateral inhibition CG5674 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0060376 l(3)SzB90Cn lethal (3) SzB90Cn http://flybase.net/reports/FBgn0060376.html gene "1357/07, l(3)S135707b" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069362 MTIP motif 2 interacting protein http://flybase.net/reports/FBgn0069362.html gene 16-Dec-15 2015_12 FBgn0036601 CG13063 http://flybase.net/reports/FBgn0036601.html protein_coding_gene IPR007614=Retinin-like protein CG13063 16-Dec-15 2015_12 viable FBgn0266140 CR44846 http://flybase.net/reports/FBgn0266140.html non_protein_coding_gene CR44846 16-Dec-15 2015_12 FBgn0066119 EP3219 EP3219 http://flybase.net/reports/FBgn0066119.html gene 16-Dec-15 2015_12 "viable,small body,female sterile,decreased cell size" FBgn0014053 Su(tor)2-321 Su(tor)2-321 http://flybase.net/reports/FBgn0014053.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0032370 CG12307 http://flybase.net/reports/FBgn0032370.html protein_coding_gene CG12307 16-Dec-15 2015_12 viable FBgn0028656 anon-35F-36Aa anon-35F-36Aa http://flybase.net/reports/FBgn0028656.html gene "unnamed, anon-35F/36Aa" 16-Dec-15 2015_12 FBgn0052482 tRNA:M-i:61D tRNA:M-i:61D http://flybase.net/reports/FBgn0052482.html "FBgn0003813, FBgn0004314, FBgn0011911, FBgn0011913, FBgn0011914, FBgn0011923, FBgn0011924, FBgn0011925, FBgn0011926, FBgn0060146" tRNA_gene "0033436=AUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3L.trna49-MetCAT, AE002584.trna21-MetCAT, tRNA:M3:61Dd, tRNA:M3:61Dg, tRNA:M:CAT:AE002584-b, tRNA:met-i:61Da, CR32482, tRNA:met3:61Dg, tRNA:M-i:61Db, tRNA:M-i:61Da, tRNA:met-i:61Db, tRNA[[i]][Met], tRNA:met3:61Df, tRNA:met-i, tRNA:M-i, transfer RNA:met3:61De, tRNA[Met-ATG], transfer RNA:met-i:61Db, tRNA:M3:61Df, tRNA:met3:61Dd, transfer RNA:met-i:61Da, initiator methionine tRNA, transfer RNA:met3:61Dd, transfer RNA:met3:61Df, tRNA:M3:61De, transfer RNA:met3:61Dg, tRNA:met3:61De" CR32482 16-Dec-15 2015_12 "developmental rate defective,large body" FBgn0264378 CR43830 http://flybase.net/reports/FBgn0264378.html non_protein_coding_gene lincRNA.311 CR43830 16-Dec-15 2015_12 FBgn0035987 CG3689 http://flybase.net/reports/FBgn0035987.html protein_coding_gene "0003729=mRNA binding, 0016787=hydrolase activity" "0006378=mRNA polyadenylation, 0006379=mRNA cleavage" 0005849=mRNA cleavage factor complex CF I[[m]]25 "IPR000086=NUDIX hydrolase domain, IPR016706=Cleavage/polyadenylation specificity factor subunit 5, IPR015797=NUDIX hydrolase domain-like" CG3689 16-Dec-15 2015_12 "ENSDARG00000003153(cpsf5),ENSDARG00000069394" WBGene00009668(cfim-1) ENSXETG00000020017(cpsf5) ENSMUSG00000031754(Nudt21) ENSG00000167005(NUDT21) "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,tormogen cell,mesothoracic tergum" FBgn0003354 sens(3)str sensitive to streptomycin http://flybase.net/reports/FBgn0003354.html gene "str[s], sensitivity (3) streptomycin" 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0060758 l(3)S063811 lethal (3) S063811 http://flybase.net/reports/FBgn0060758.html gene 0638/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0265839 CR44628 http://flybase.net/reports/FBgn0265839.html non_protein_coding_gene CR44628 16-Dec-15 2015_12 FBgn0033588 CG13228 http://flybase.net/reports/FBgn0033588.html protein_coding_gene CG13228 16-Dec-15 2015_12 viable FBgn0001946 l(2)27Ca lethal (2) 27Ca http://flybase.net/reports/FBgn0001946.html gene "A, Complementation group A" 16-Dec-15 2015_12 lethal FBgn0028903 CG13243 http://flybase.net/reports/FBgn0028903.html protein_coding_gene BG:DS02252.1 "IPR003117=cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG13243 16-Dec-15 2015_12 ENSG00000158428(C2orf62) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016864 l(2)39ADb lethal (2) 39ADb http://flybase.net/reports/FBgn0016864.html gene J50 16-Dec-15 2015_12 lethal FBgn0030483 CG12725 http://flybase.net/reports/FBgn0030483.html protein_coding_gene "IPR029071=Ubiquitin-related domain, IPR000626=Ubiquitin domain" CG12725 16-Dec-15 2015_12 viable FBgn0262327 mir-2281 mir-2281 stem loop http://flybase.net/reports/FBgn0262327.html miRNA_gene "miR-2281, CR43034, dme-mir-2281" CR43034 16-Dec-15 2015_12 viable FBgn0028251 l(3)90Ea lethal (3) 90Ea http://flybase.net/reports/FBgn0028251.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0003128 port-b port b http://flybase.net/reports/FBgn0003128.html gene 16-Dec-15 2015_12 "visible,eye color defective" pigment cell FBgn0038425 CG14881 http://flybase.net/reports/FBgn0038425.html protein_coding_gene "IPR002539=MaoC-like domain, IPR011989=Armadillo-like helical, IPR029069=HotDog domain, IPR016024=Armadillo-type fold" CG14881 16-Dec-15 2015_12 viable FBgn0260970 Ubr3 Ubr3 ubiquitin ligase http://flybase.net/reports/FBgn0260970.html "FBgn0029985, FBgn0029983" protein_coding_gene 0008270=zinc ion binding "0016567=protein ubiquitination, 0043066=negative regulation of apoptotic process" "ubr3, CG1531, CG1530, CG42593" "IPR001841=Zinc finger, RING-type, IPR003126=Zinc finger, UBR-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG42593 16-Dec-15 2015_12 WBGene00017373(F10G7.10) ENSXETG00000018856(UBR3) ENSMUSG00000044308(Ubr3) ENSG00000144357(UBR3) FBgn0031822 CG9548 http://flybase.net/reports/FBgn0031822.html FBgn0062970 protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" BcDNA:RH02789 IPR005345=PHF5-like CG9548 16-Dec-15 2015_12 ENSDARG00000045155(phf5a) YPR094W(RDS3) WBGene00004016(phf-5) ENSXETG00000006893(PHF5A) ENSMUSG00000061360(Phf5a) ENSG00000100410(PHF5A) "lethal - all die before end of pupal stage,some die during pupal stage,female fertile" DRSC03261 I -0.257919123 1.945898208 0.022653043 0.447401283 0.499423496 -0.531294774 FBgn0037746 CG8478 http://flybase.net/reports/FBgn0037746.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG8478 16-Dec-15 2015_12 viable FBgn0044103 E(rst)C45 E(rst)C45 http://flybase.net/reports/FBgn0044103.html gene 0001745=compound eye morphogenesis C45 16-Dec-15 2015_12 viable eye FBgn0069443 E(br)72 E(br)72 http://flybase.net/reports/FBgn0069443.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267490 Mst77Y-4 Male-specific transcript 77Y 4 http://flybase.net/reports/FBgn0267490.html "FBgn0262753, FBgn0267410" protein_coding_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin CG45763 CG45763 16-Dec-15 2015_12 FBgn0035811 CG12262 http://flybase.net/reports/FBgn0035811.html protein_coding_gene "0003995=acyl-CoA dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" 0006635=fatty acid beta-oxidation "0005739=mitochondrion, 0005811=lipid particle, 0005875=microtubule associated complex" "CG 12262, ACAD, MCAD, acyl-CoA dehdrogenase, medium chain acyl-CoA dehydrogenase" "IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR006089=Acyl-CoA dehydrogenase, conserved site, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain" CG12262 16-Dec-15 2015_12 ENSDARG00000038900(acadm) "WBGene00020366(acdh-10),WBGene00019406(acdh-8),WBGene00020812(acdh-7)" ENSXETG00000002983(ACADM) ENSMUSG00000062908(Acadm) ENSG00000117054(ACADM) viable FBgn0022807 E(faf)bE365 Enhancer of faf bE365 http://flybase.net/reports/FBgn0022807.html gene 16-Dec-15 2015_12 viable FBgn0038694 CG5217 http://flybase.net/reports/FBgn0038694.html FBgn0044688 protein_coding_gene anon-WO0140519.188 CG5217 16-Dec-15 2015_12 viable FBgn0067744 l(1)G0275 lethal (1) G0275 http://flybase.net/reports/FBgn0067744.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085709 CG41584 http://flybase.net/reports/FBgn0085709.html FBan0041584 protein_coding_gene 16-Dec-15 2015_12 FBgn0011232 scat scattered http://flybase.net/reports/FBgn0011232.html FBgn0032118 protein_coding_gene "0042147=retrograde transport, endosome to Golgi, 0007286=spermatid development, 0007291=sperm individualization, 0006896=Golgi to vacuole transport" "0005739=mitochondrion, 0005794=Golgi apparatus" "ms(2)30B, ms(2)05289, Scat, CG3766, Vps54, Scattered" "IPR015880=Zinc finger, C2H2-like, IPR012501=Vps54-like, IPR019515=Vacuolar protein sorting-associated protein 54" CG3766 16-Dec-15 2015_12 ENSDARG00000002980(zgc:195037) WBGene00006934(vps-54) ENSXETG00000013000(VPS54) ENSMUSG00000020128(Vps54) ENSG00000143952(VPS54) "male sterile,recessive,partially lethal - majority die,viable,fertile" "spermatozoon,primary spermatocyte cyst,spermatid" FBgn0010815 l(3)03719 lethal (3) 03719 http://flybase.net/reports/FBgn0010815.html FBgn0011345 gene 0007365=periodic partitioning "l(3)j3B3, unnamed" 16-Dec-15 2015_12 "lethal,recessive,maternal effect" "embryonic/first instar larval cuticle,maternal effect,segment" FBgn0060351 l(3)S142206 lethal (3) S142206 http://flybase.net/reports/FBgn0060351.html gene 1422/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267240 CR45680 http://flybase.net/reports/FBgn0267240.html non_protein_coding_gene CR45680 16-Dec-15 2015_12 FBgn0033194 Vps13 Vacuolar protein sorting 13 http://flybase.net/reports/FBgn0033194.html FBgn0046277 protein_coding_gene 0006623=protein targeting to vacuole "BEST:LD02743, CG2093, Vps13" "IPR026847=Vacuolar protein sorting-associated protein 13, IPR009543=Vacuolar protein sorting-associated protein 13, SHR-binding domain, IPR026854=Vacuolar protein sorting-associated protein 13A, N-terminal domain" CG2093 16-Dec-15 2015_12 YLL040C(VPS13) WBGene00011629(T08G11.1) "ENSXETG00000005221(),ENSXETG00000003616()" ENSMUSG00000046230(Vps13a) ENSG00000197969(VPS13A) viable FBgn0035969 CG4476 http://flybase.net/reports/FBgn0035969.html FBgn0045952 protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005416=cation:amino acid symporter activity, 0017032=potassium:amino acid symporter activity, 0005326=neurotransmitter transporter activity" "0006836=neurotransmitter transport, 0007632=visual behavior, 0044745=amino acid transmembrane import" "0016021=integral component of membrane, 0005886=plasma membrane" "DmNAT3, anon-WO0149848.7" IPR000175=Sodium:neurotransmitter symporter CG4476 16-Dec-15 2015_12 "viable,fertile,visual behavior defective" DRSC10424 E -0.215300238 -0.442615215 2.628437419 0.661281863 -0.245176889 -1.087931906 FBgn0027330 l(1)G0020 lethal (1) G0020 http://flybase.net/reports/FBgn0027330.html FBgn0030062 protein_coding_gene "0004402=histone acetyltransferase activity, 0008080=N-acetyltransferase activity" "0009267=cellular response to starvation, 0022008=neurogenesis" 0005634=nucleus "NAT10, CG1994, p110" "IPR000182=GNAT domain, IPR027992=Possible tRNA binding domain, IPR013562=Domain of unknown function DUF1726, IPR007807=Helicase domain, IPR016181=Acyl-CoA N-acyltransferase" CG1994 16-Dec-15 2015_12 ENSDARG00000054259(nat10) YNL132W(KRE33) WBGene00018866(F55A12.8) ENSXETG00000003782(NAT10) ENSMUSG00000027185(Nat10) ENSG00000135372(NAT10) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0031292 CG15824 http://flybase.net/reports/FBgn0031292.html protein_coding_gene CG15824 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0004065 Gsg71A Gastrula-specific transcript 71A http://flybase.net/reports/FBgn0004065.html gene gsg71A 16-Dec-15 2015_12 FBgn0036972 CR6434 http://flybase.net/reports/FBgn0036972.html pseudogene_attribute 0046427=positive regulation of JAK-STAT cascade "CG6434, mdcds_29715" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain" CR6434 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0263547 mir-4944 mir-4944 stem loop http://flybase.net/reports/FBgn0263547.html miRNA_gene "dme-mir-4944, CR43532" CR43532 16-Dec-15 2015_12 FBgn0262604 CR43130 http://flybase.net/reports/FBgn0262604.html non_protein_coding_gene CG43130 CR43130 16-Dec-15 2015_12 FBgn0038748 CG12378 http://flybase.net/reports/FBgn0038748.html protein_coding_gene 16-Dec-15 2015_12 FBgn0013482 l(1)3P5 lethal (1) 3P5 http://flybase.net/reports/FBgn0013482.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,rescuable maternal effect" FBgn0004047 Yp3 Yolk protein 3 http://flybase.net/reports/FBgn0004047.html FBgn0000781 protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0005198=structural molecule activity" "0007548=sex differentiation, 0007296=vitellogenesis, 0045995=regulation of embryonic development, 0009617=response to bacterium, 0022008=neurogenesis" "0005576=extracellular region, 0005811=lipid particle, 0005875=microtubule associated complex, 0043186=P granule" "YP[[3]], unnamed, yolk protein, yolk protein 3, VG3, fs(1)1526, YP-3, YP, YP3, yp, vitellogenin, yp3, fs(1)A1526, CG11129, VIT3Dm, DIM 30" "IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold" CG11129 16-Dec-15 2015_12 "electrophoretic variant,lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0032851 CG13970 http://flybase.net/reports/FBgn0032851.html protein_coding_gene 38B.19 CG13970 16-Dec-15 2015_12 viable FBgn0038983 CG5326 http://flybase.net/reports/FBgn0038983.html protein_coding_gene 0009922=fatty acid elongase activity "0022008=neurogenesis, 0030497=fatty acid elongation" 0016021=integral component of membrane IPR002076=ELO family CG5326 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001883 l(1)YQ09 lethal (1) YQ09 http://flybase.net/reports/FBgn0001883.html gene 16-Dec-15 2015_12 lethal FBgn0051639 CG31639 http://flybase.net/reports/FBgn0051639.html "FBgn0045143, FBgn0045219" protein_coding_gene "0008242=omega peptidase activity, 0004843=ubiquitin-specific protease activity" 0006511=ubiquitin-dependent protein catabolic process 0005622=intracellular "NEST:bs21c05, NEST:bs29d12" "IPR017390=Ubiquitinyl hydrolase, UCH37 type, IPR001578=Peptidase C12, ubiquitin carboxyl-terminal hydrolase" CG31639 16-Dec-15 2015_12 viable FBgn0053771 CG33771 http://flybase.net/reports/FBgn0053771.html FBgn0037173 protein_coding_gene CG14458 "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG33771 16-Dec-15 2015_12 viable FBgn0005524 l(2)52ACa lethal (2) 52ACa http://flybase.net/reports/FBgn0005524.html gene unnamed 16-Dec-15 2015_12 FBgn0050349 CG30349 http://flybase.net/reports/FBgn0050349.html "FBgn0033343, FBgn0033345, FBgn0063640" protein_coding_gene 0009267=cellular response to starvation "CG2396, CG13750" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR007148=Small-subunit processome, Utp12" CG30349 16-Dec-15 2015_12 ENSDARG00000059129 ENSMUSG00000041057(Wdr43) ENSG00000163811(WDR43) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039406 RpL34a Ribosomal protein L34a http://flybase.net/reports/FBgn0039406.html protein_coding_gene "0017022=myosin binding, 0003735=structural constituent of ribosome" 0006412=translation 0022625=cytosolic large ribosomal subunit "L34, CG6090, RpL34" "IPR008195=Ribosomal protein L34Ae, IPR018065=Ribosomal protein L34e, conserved site" CG6090 16-Dec-15 2015_12 ENSDARG00000029500(rpl34) "YIL052C(RPL34B),YER056C-A(RPL34A)" WBGene00004448(rpl-34) "ENSXETG00000021095(rpl34a),ENSXETG00000020482()" "ENSMUSG00000062006(Rpl34),ENSMUSG00000066116(Gm10154),ENSMUSG00000060730(Gm10086),ENSMUSG00000061669(Gm6404),ENSMUSG00000078128(Gm2178)" ENSG00000109475(RPL34) lethal FBgn0036479 CG13458 http://flybase.net/reports/FBgn0036479.html protein_coding_gene "IPR002893=Zinc finger, MYND-type" CG13458 16-Dec-15 2015_12 ENSXETG00000009165(ZMYND17) ENSMUSG00000021815(Zmynd17) ENSG00000166343(ZMYND17) "viable,fertile" FBgn0046629 anon-38E.8 anon-38E.8 http://flybase.net/reports/FBgn0046629.html gene 38E.8 16-Dec-15 2015_12 FBgn0020052 E(wa)829 E(wa)829 http://flybase.net/reports/FBgn0020052.html gene E829 16-Dec-15 2015_12 "lethal,recessive,eye color defective" pigment cell FBgn0267123 CR45563 http://flybase.net/reports/FBgn0267123.html non_protein_coding_gene CR45563 16-Dec-15 2015_12 FBgn0001595 l(1)carot12 lethal (1) carot12 http://flybase.net/reports/FBgn0001595.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032260 CG13144 http://flybase.net/reports/FBgn0032260.html protein_coding_gene CG13144 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02241 K -0.811305917 -0.288616302 0.764629073 0.605461656 0.514386673 -2.522339945 FBgn0259788 anon-A24 http://flybase.net/reports/FBgn0259788.html gene DmA24 16-Dec-15 2015_12 FBgn0065474 l(2)SH1314 lethal (2) SH1314 http://flybase.net/reports/FBgn0065474.html gene l(2)SH2 1314 16-Dec-15 2015_12 "lethal,recessive" FBgn0053372 5SrRNA:CR33372 5SrRNA:CR33372 http://flybase.net/reports/FBgn0053372.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33372 CR33372 16-Dec-15 2015_12 FBgn0022936 CycH Cyclin H http://flybase.net/reports/FBgn0022936.html protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0004693=cyclin-dependent protein serine/threonine kinase activity, 0019901=protein kinase binding, 0000990=core RNA polymerase binding transcription factor activity, 0008353=RNA polymerase II carboxy-terminal domain kinase activity" "0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" "0032806=carboxy-terminal domain protein kinase complex, 0005675=holo TFIIH complex, 0070985=TFIIK complex" "CG7405, CyclinH, CCNH, cyclin-H, cyclin H, 142767_at" "IPR027081=CyclinH/Ccl1, IPR006671=Cyclin, N-terminal, IPR015429=Cyclin C/H/T/L, IPR013763=Cyclin-like" CG7405 16-Dec-15 2015_12 ENSDARG00000007657(ccnh) YPR025C(CCL1) WBGene00021714(cyh-1) ENSXETG00000011718(ccnh) ENSMUSG00000021548(Ccnh) ENSG00000134480(CCNH) "increased cell death,viable" spermatogonium FBgn0030778 CG4678 http://flybase.net/reports/FBgn0030778.html protein_coding_gene "0004185=serine-type carboxypeptidase activity, 0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR000834=Peptidase M14, carboxypeptidase A, IPR014766=Carboxypeptidase, regulatory domain, IPR027062=Carboxypeptidase M, IPR008969=Carboxypeptidase-like, regulatory domain" CG4678 16-Dec-15 2015_12 ENSDARG00000011769(zgc:110307) WBGene00012073(T27A8.1) ENSXETG00000001438(cpm) ENSMUSG00000020183(Cpm) ENSG00000135678(CPM) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" DRSC19911 K -0.151640671 0.10520871 0.551603192 0.155784418 1.55142103 0.568742998 FBgn0001955 l(2)28Ba lethal (2) 28Ba http://flybase.net/reports/FBgn0001955.html gene "Complementation group M, M" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051745 CG31745 http://flybase.net/reports/FBgn0051745.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265728 CR44535 http://flybase.net/reports/FBgn0265728.html non_protein_coding_gene "lincRNA.418, incRNA.418" CR44535 16-Dec-15 2015_12 FBgn0261272 esi-2 endogenous siRNA 2 http://flybase.net/reports/FBgn0261272.html gene "CG4068 'B' endo-siRNA, hp-CG4068G, hp-CG4068B, hp-CG4068, esi CG4068-B, esl-2, hpCG4068B, esiRNA-sl-1, esi-2.1, esi-sl-1, CG4068B, esiRNA-sl, esi-sl-4, esi-sl-4as" 16-Dec-15 2015_12 FBgn0033855 link link http://flybase.net/reports/FBgn0033855.html protein_coding_gene 0022008=neurogenesis 0031982=vesicle CG13333 CG13333 16-Dec-15 2015_12 "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC06368 IE 3.559409506 2.719408951 2.505935109 -1.426940535 -0.40172273 0.9166344 FBgn0028570 robl22E robl22E http://flybase.net/reports/FBgn0028570.html FBgn0031411 protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex "CG10838, Robl22E" "IPR016561=Dynein light chain roadblock-type 1/2, IPR004942=Roadblock/LAMTOR2 domain" CG10838 16-Dec-15 2015_12 WBGene00012004(dyrb-1) viable FBgn0259714 DIP-ëµ Dpr-interacting protein ëµ http://flybase.net/reports/FBgn0259714.html "FBgn0031810, FBgn0031809, FBan0009511, FBgn0031807, FBgn0053295" protein_coding_gene "42368, CG13981, CG42368, CG33295, CG9508, DIP-epsilon, CG9511" "IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set" CG42368 16-Dec-15 2015_12 WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" "viable,visible" mesothoracic tergum """DRSC02313, DRSC00932, DRSC29110"" " IEK FBgn0036679 CG13022 http://flybase.net/reports/FBgn0036679.html protein_coding_gene CG13022 16-Dec-15 2015_12 viable FBgn0069449 E(br)187 E(br)187 http://flybase.net/reports/FBgn0069449.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262810 CG43181 http://flybase.net/reports/FBgn0262810.html protein_coding_gene chrX_244575_245164.0 CG43181 16-Dec-15 2015_12 FBgn0032633 Lrch Leucine-rich-repeats and calponin homology domain protein http://flybase.net/reports/FBgn0032633.html protein_coding_gene 0007265=Ras protein signal transduction "0032154=cleavage furrow, 0005938=cell cortex" "CT21229, CG6860, dLRCH" "IPR001611=Leucine-rich repeat, IPR001715=Calponin homology domain, IPR003591=Leucine-rich repeat, typical subtype, IPR000595=Cyclic nucleotide-binding domain" CG6860 16-Dec-15 2015_12 "ENSDARG00000068389,ENSDARG00000068258(si:dkeyp-73c8.2)" WBGene00015779(C14F11.2) "ENSXETG00000011477(LRCH1),ENSXETG00000010141(lrch1)" "ENSMUSG00000022801(Lrch3),ENSMUSG00000031290(Lrch2),ENSMUSG00000029720(Lrch4)" "ENSG00000136141(LRCH1),ENSG00000130224(LRCH2)" viable FBgn0037222 CG14642 http://flybase.net/reports/FBgn0037222.html FBan0014642 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP29 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG14642 16-Dec-15 2015_12 viable FBgn0053414 5SrRNA:CR33414 5SrRNA:CR33414 http://flybase.net/reports/FBgn0053414.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33414 CR33414 16-Dec-15 2015_12 FBgn0004534 l(4)102ABf lethal (4) 102ABf http://flybase.net/reports/FBgn0004534.html gene l(4)20 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004687 Mlc-c Myosin light chain cytoplasmic http://flybase.net/reports/FBgn0004687.html protein_coding_gene "0005515=protein binding, 0017022=myosin binding, 0032036=myosin heavy chain binding, 0005509=calcium ion binding" 0030048=actin filament-based movement "0016459=myosin complex, 0016461=unconventional myosin complex, 0031475=myosin V complex, 0031476=myosin VI complex, 0031477=myosin VII complex, 0016460=myosin II complex" "MyoII, myosin II, non-muscle Myosin II, alkali light chain of non-muscle myosin-II, Myosin, Myosin light chain-cytoplasmic, mlc-c, CG3201, DmMLC_C, essential light chain-cytoplasmic, Myosin II, nmELC, essential myosin light chain-cytoplasmic, Myosin-II" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG3201 16-Dec-15 2015_12 "ENSDARG00000033738(zgc:153867),ENSDARG00000008494(zgc:103624),ENSDARG00000032976(cmlc1),ENSDARG00000070679(LOC100148520),ENSDARG00000011519(zgc:114164),ENSDARG00000042245,ENSDARG00000014196(zgc:77231),ENSDARG00000029321(zgc:163073),ENSDARG00000017441(mylz3)" WBGene00011734(T12D8.6) "ENSXETG00000024654(BC061440.1),ENSXETG00000003242(MYL4),ENSXETG00000006917(myl1),ENSXETG00000003682(BC061446.1)" "ENSMUSG00000039824(Myl6b),ENSMUSG00000059741(Myl3),ENSMUSG00000061816(Myl1),ENSMUSG00000061086(Myl4),ENSMUSG00000060680" "ENSG00000092841(MYL6),ENSG00000196465(MYL6B),ENSG00000198336(MYL4),ENSG00000168530(MYL1),ENSG00000160808(MYL3)" viable FBgn0001117 gn glisten http://flybase.net/reports/FBgn0001117.html gene 16-Dec-15 2015_12 visible "eye,ommatidium,interommatidial bristle" FBgn0265067 CR44178 http://flybase.net/reports/FBgn0265067.html non_protein_coding_gene CG44178 CR44178 16-Dec-15 2015_12 FBgn0031623 Taf12L TBP-associated factor 30kD subunit ë±-2 http://flybase.net/reports/FBgn0031623.html protein_coding_gene 0046982=protein heterodimerization activity "0007283=spermatogenesis, 0006367=transcription initiation from RNA polymerase II promoter, 0007140=male meiosis" "0001673=male germ cell nucleus, 0005669=transcription factor TFIID complex" "TBP-associated factor 30kD subunit alpha-2, TBP-associated factor subunit alpha-2, TFIID, dmTAF12L, TAF, Rye, TAF30alpha-2, dTAF12, TAF12L, dTAF12L, dTAF[[II]]30a, TAF[[II]], rye, dTAF[[II]]30alpha-2, ryan express, Taf30alpha-2, TBP-associated factor, dmTAF12b, CG15632" "IPR003228=Transcription initiation factor TFIID, IPR009072=Histone-fold" CG15632 16-Dec-15 2015_12 FBgn0032276 CG17098 http://flybase.net/reports/FBgn0032276.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "IPR015880=Zinc finger, C2H2-like, IPR003604=Zinc finger, U1-type, IPR007087=Zinc finger, C2H2" CG17098 16-Dec-15 2015_12 DRSC02570 K -0.776278929 0.104380633 0.143300691 0.649355764 1.628176788 0.590614665 FBgn0264386 Ca-ë±1T Ca2+-channel protein ë±1 subunit T http://flybase.net/reports/FBgn0264386.html "FBgn0029846, FBgn0029844, FBgn0029845, FBgn0041343" protein_coding_gene "0008332=low voltage-gated calcium channel activity, 0005262=calcium channel activity" "0070588=calcium ion transmembrane transport, 0070509=calcium ion import" 0005891=voltage-gated calcium channel complex "CG12544, cat, Dmca1G, alpha1T, CG4222, Ca-alphaT-RC, DmalphaG, Ca1G, CG15899, Caalpha1T, Ca-alpha1T" "IPR005445=Voltage-dependent calcium channel, T-type, alpha-1 subunit, IPR005821=Ion transport domain, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR030154=Voltage-dependent calcium channel,T-type, alpha-1G subunit" CG15899 16-Dec-15 2015_12 ENSDARG00000071469 YGR217W(CCH1) WBGene00000367(cca-1) "ENSXETG00000006824(CACNA1G),ENSXETG00000022646(CACNA1H),ENSXETG00000016133(CACNA1I)" "ENSMUSG00000020866(Cacna1g),ENSMUSG00000024112(Cacna1h),ENSMUSG00000022416(Cacna1i)" "ENSG00000006283(CACNA1G),ENSG00000196557(CACNA1H),ENSG00000100346(CACNA1I)" DRSC17842 K 0.080944759 -0.370035843 -0.064673309 -0.315747088 -1.76304499 -0.56085166 FBgn0039712 CG15514 http://flybase.net/reports/FBgn0039712.html protein_coding_gene 0003677=DNA binding "IPR015880=Zinc finger, C2H2-like, IPR003656=Zinc finger, BED-type" CG15514 16-Dec-15 2015_12 viable FBgn0264669 wavy-lumens wavy lumens http://flybase.net/reports/FBgn0264669.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040699 CG15024 http://flybase.net/reports/FBgn0040699.html protein_coding_gene CG15024 16-Dec-15 2015_12 viable FBgn0085405 CG34376 http://flybase.net/reports/FBgn0085405.html "FBgn0038969, FBgn0038970, FBgn0038971, FBgn0051160" protein_coding_gene "CG13845, CG13851, CG31160, CG13846" "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR007588=Zinc finger, FLYWCH-type" CG34376 16-Dec-15 2015_12 ENSXETG00000000723(NACC2) ENSG00000160877(NACC1) FBgn0267963 CR46243 http://flybase.net/reports/FBgn0267963.html non_protein_coding_gene lincRNA.940 CR46243 16-Dec-15 2015_12 FBgn0038195 CG3061 http://flybase.net/reports/FBgn0038195.html protein_coding_gene 0012505=endomembrane system dnaJ like2 "IPR015399=Domain of unknown function DUF1977, DnaJ-like, IPR001623=DnaJ domain" CG3061 16-Dec-15 2015_12 "ENSDARG00000039363(dnajb12),ENSDARG00000008312(zgc:163044),ENSDARG00000069996(zgc:153638),ENSDARG00000056005(dnajc18)" YMR161W(HLJ1) WBGene00001019(dnj-1) "ENSXETG00000006151(dnajb12),ENSXETG00000009306(TEgg043m09.1)" "ENSMUSG00000020109(Dnajb12),ENSMUSG00000074212(Dnajb14)" "ENSG00000148719(DNAJB12),ENSG00000164031(DNAJB14)" viable FBgn0085367 CG34338 http://flybase.net/reports/FBgn0085367.html protein_coding_gene CG34338 16-Dec-15 2015_12 FBgn0045033 ultB ultrahair B http://flybase.net/reports/FBgn0045033.html FBgn0016074 gene "uhr, ultrahair" 16-Dec-15 2015_12 FBgn0051974 CG31974 http://flybase.net/reports/FBgn0051974.html FBgn0031223 protein_coding_gene CG18501 "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG31974 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0082944 snoRNA:Me28S-A2634c snoRNA:Me28S-A2634c http://flybase.net/reports/FBgn0082944.html snoRNA_gene "Me28S-A2634c, CR34634, Me28S-Am2634c" CR34634 16-Dec-15 2015_12 FBgn0011561 adm all discs missing http://flybase.net/reports/FBgn0011561.html gene 0007446=imaginal disc growth 16-Dec-15 2015_12 FBgn0036334 CG11267 http://flybase.net/reports/FBgn0036334.html FBgn0062191 protein_coding_gene 0051082=unfolded protein binding 0006458='de novo' protein folding "0005811=lipid particle, 0005739=mitochondrion, 0005759=mitochondrial matrix" "anon-WO0118547.175, Hsp10" "IPR011032=GroES-like, IPR020818=Chaperonin Cpn10" CG11267 16-Dec-15 2015_12 ENSDARG00000056167(hspe1) YOR020C(HSP10) WBGene00021248(Y22D7AL.10) ENSXETG00000007510(hspe1) "ENSMUSG00000073676(Hspe1),ENSMUSG00000049246(Hspe1-rs1)" "ENSG00000115541(HSPE1),ENSG00000217897" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0035581 CG17150 http://flybase.net/reports/FBgn0035581.html protein_coding_gene "0042623=ATPase activity, coupled, 0003777=microtubule motor activity, 0003774=motor activity" 0007018=microtubule-based movement "0030286=dynein complex, 0005875=microtubule associated complex" "IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR004273=Dynein heavy chain domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG17150 16-Dec-15 2015_12 ENSG00000158486(DNAH3) "viable,fertile" FBgn0014908 anon-4Fb anon-4Fb http://flybase.net/reports/FBgn0014908.html gene 16-Dec-15 2015_12 FBgn0041098 quiescin quiescin http://flybase.net/reports/FBgn0041098.html gene 0003756=protein disulfide isomerase activity PDI(II) 16-Dec-15 2015_12 FBgn0020546 iab-4 iab-4 http://flybase.net/reports/FBgn0020546.html "FBan0031271, FBgn0051271" non_protein_coding_gene "pri-mir-iab-4_mir-iab-4as, iab, domain I, I, CR31271" CR31271 16-Dec-15 2015_12 " embryonic stage | stage 1-17 , embryonic stage | stage stage 8 , embryonic stage | stage 4 , embryonic stage | stage 8 " " parasegment 8-14 &&of embryonic ventral nervous system

,

posterior , parasegment 8--14

,

10-60% egg length " "viable,visible,homeotic,male sterile,female sterile,recessive" "adult abdominal segment 2,adult abdominal segment 5,adult abdominal segment 4,gonad,precursor,pole cell,adult abdominal segment 1,ovary,oviduct,testis" FBgn0039532 Mtl Mig-2-like http://flybase.net/reports/FBgn0039532.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0007391=dorsal closure, 0090303=positive regulation of wound healing, 0008258=head involution, 0007394=dorsal closure, elongation of leading edge cells, 0031532=actin cytoskeleton reorganization, 0007435=salivary gland morphogenesis, 0001737=establishment of imaginal disc-derived wing hair orientation, 0007390=germ-band shortening, 0002009=morphogenesis of an epithelium, 0051017=actin filament bundle assembly, 0030032=lamellipodium assembly, 0007264=small GTPase mediated signal transduction, 0007254=JNK cascade, 0035099=hemocyte migration, 0006974=cellular response to DNA damage stimulus, 0042067=establishment of ommatidial planar polarity" 0005622=intracellular "Mtl(Rac-like), mig-2-like, Rac, dMig-2, Mig-2-like, MTL, CG5588, 5588, mtl, Mt1/Mig2-like, Rac-like, Rac GTPase" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain" CG5588 16-Dec-15 2015_12 WBGene00003239(mig-2) "viable,fertile,planar polarity defective,wild-type,cell shape defective" "eye,ommatidium,wing hair,supernumerary,longitudinal connective,adult mushroom body,presumptive embryonic salivary gland" FBgn0267661 CR45999 http://flybase.net/reports/FBgn0267661.html non_protein_coding_gene CR45999 16-Dec-15 2015_12 FBgn0051130 tRNA:CR31130 transfer RNA:CR31130 http://flybase.net/reports/FBgn0051130.html FBgn0060151 tRNA_gene 0033403=UUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3R.trna35-LeuTAA, tRNA:L:TAA:AE002708-b, AE002708.trna29-LeuTAA, CR31130" CR31130 16-Dec-15 2015_12 FBgn0038257 smp-30 Senescence marker protein-30 http://flybase.net/reports/FBgn0038257.html protein_coding_gene 0005509=calcium ion binding "0044720=negative regulation of imaginal disc-derived wing size, 0090256=regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis, 0009631=cold acclimation" 0005829=cytosol "Dca, senescence marker protein-30, CT22723, CG7390, Smp-30, Drosophila cold acclimation gene, cold acclimation" "IPR013658=SMP-30/Gluconolactonase/LRE-like region, IPR005511=Senescence marker protein-30 (SMP-30), IPR018391=Pyrrolo-quinoline quinone beta-propeller repeat, IPR011042=Six-bladed beta-propeller, TolB-like" CG7390 16-Dec-15 2015_12 "ENSDARG00000071154,ENSDARG00000071147,ENSDARG00000071137,ENSDARG00000032200(rgn)" ENSXETG00000004127(Q6DF62_XENTR) ENSMUSG00000023070(Rgn) ENSG00000130988(RGN) "size defective,viable" wing FBgn0062618 Mod(var)1205 Mod(var)1205 http://flybase.net/reports/FBgn0062618.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1205 16-Dec-15 2015_12 "viable,reduced,suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0069453 E(br)121 E(br)121 http://flybase.net/reports/FBgn0069453.html gene 16-Dec-15 2015_12 "visible,semidominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" leg FBgn0058195 CG40195 http://flybase.net/reports/FBgn0058195.html FBan0040195 protein_coding_gene 16-Dec-15 2015_12 FBgn0259219 CG42319 http://flybase.net/reports/FBgn0259219.html "FBgn0033822, FBgn0033823" protein_coding_gene "CG17041, CG17042" IPR001478=PDZ domain CG42319 16-Dec-15 2015_12 "ENSG00000196923(PDLIM7),ENSG00000163110(PDLIM5),ENSG00000122367(LDB3),ENSG00000154553(PDLIM3)" FBgn0263608 l(3)72Dr lethal (3) 72Dr http://flybase.net/reports/FBgn0263608.html "FBgn0260650, FBgn0052154, FBgn0036582" protein_coding_gene 0008242=omega peptidase activity 0006541=glutamine metabolic process "CG5082, CG32154" "IPR011697=Peptidase C26, IPR029062=Class I glutamine amidotransferase-like, IPR015527=Peptidase C26, gamma-glutamyl hydrolase" CG32154 16-Dec-15 2015_12 FBgn0011185 l(1)294-31 lethal (1) 294-31 http://flybase.net/reports/FBgn0011185.html FBgn0010200 gene 294-31 16-Dec-15 2015_12 "lethal,recessive" FBgn0025514 fs(3)82EFb fs(3)82EFb http://flybase.net/reports/FBgn0025514.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0030026 sni sniffer http://flybase.net/reports/FBgn0030026.html FBgn0066834 protein_coding_gene 0004090=carbonyl reductase (NADPH) activity 0008152=metabolic process "SNI, anon-WO03040301.183, Sniffer, CG10964, Sni" "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG10964 16-Dec-15 2015_12 "ENSDARG00000046030(zgc:110339),ENSDARG00000041073(si:dkey-12e7.4)" YKL071W() "WBGene00008986(F20G2.2),WBGene00008985(F20G2.1),WBGene00022809(ZK697.14),WBGene00016274(C30G12.2),WBGene00008334(sdz-8),WBGene00008335(C55A6.6),WBGene00008332(C55A6.3),WBGene00008333(C55A6.4),WBGene00008336(C55A6.7),WBGene00000975(dhs-12)" ENSXETG00000025643() "viable,short lived,neuroanatomy defective,increased cell death,chemical sensitive,gravitaxis defective,locomotor behavior defective,long lived,conditional,chemical resistant" "lamina monopolar neuron,lamina & glial cell" FBgn0051461 CG31461 http://flybase.net/reports/FBgn0051461.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0032214 CG4968 http://flybase.net/reports/FBgn0032214.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0006520=cellular amino acid metabolic process, 0071108=protein K48-linked deubiquitination" Q9VL00 "IPR003323=OTU domain, IPR016615=Ubiquitin thioesterase Otubain, IPR019400=Peptidase C65, otubain" CG4968 16-Dec-15 2015_12 "ENSDARG00000055536(otub1l),ENSDARG00000011462(otub1)" WBGene00007718(otub-1) ENSXETG00000008283(OTUB1) ENSMUSG00000024767(Otub1) ENSG00000167770(OTUB1) viable FBgn0037918 CG6791 http://flybase.net/reports/FBgn0037918.html protein_coding_gene 0046872=metal ion binding "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG6791 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0061107 l(3)S007915 lethal (3) S007915 http://flybase.net/reports/FBgn0061107.html gene 0079/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0262572 CG43112 http://flybase.net/reports/FBgn0262572.html protein_coding_gene MIP12787 CG43112 16-Dec-15 2015_12 FBgn0025176 l(1)TW24 lethal (1) TW24 http://flybase.net/reports/FBgn0025176.html gene 16-Dec-15 2015_12 lethal FBgn0262951 CR43270 http://flybase.net/reports/FBgn0262951.html non_protein_coding_gene pri-mir-958 CR43270 16-Dec-15 2015_12 FBgn0034084 CG8435 http://flybase.net/reports/FBgn0034084.html protein_coding_gene 0022008=neurogenesis IPR007590=CWC16 protein CG8435 16-Dec-15 2015_12 ENSDARG00000026185(ccdc94) YKL095W(YJU2) WBGene00018149(F37C12.1) ENSXETG00000011235(CCDC94) ENSMUSG00000003208(Ccdc94) ENSG00000105248(CCDC94) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC07179 E 0.985389042 1.381681456 0.232652494 1.652620704 0.17262788 -0.091062901 FBgn0264365 CR43817 http://flybase.net/reports/FBgn0264365.html non_protein_coding_gene CR43817 16-Dec-15 2015_12 FBgn0005193 l(2)S59 lethal of Seto 59 http://flybase.net/reports/FBgn0005193.html gene 16-Dec-15 2015_12 lethal "wing,leg" FBgn0001423 l(1)6Dg lethal (1) 6Dg http://flybase.net/reports/FBgn0001423.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,maternal effect" "egg,germline clone,maternal effect,female reproductive system,ovariole" FBgn0001514 l(1)10Fh lethal (1) 10Fh http://flybase.net/reports/FBgn0001514.html gene 16-Dec-15 2015_12 lethal FBgn0040508 ACXC ACXC http://flybase.net/reports/FBgn0040508.html FBgn0032458 protein_coding_gene 0004016=adenylate cyclase activity "0035556=intracellular signal transduction, 0007283=spermatogenesis, 0009190=cyclic nucleotide biosynthetic process" 0016021=integral component of membrane "Acxc, CG5983, AC, DACXC" "IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG5983 16-Dec-15 2015_12 " adult stage | male && spermatogenesis , larval stage | late , pupal stage , adult stage | male " " spermatocyte

, spermatid

" viable FBgn0262408 mir-5 mir-5 stem loop http://flybase.net/reports/FBgn0262408.html "FBgn0046820, FBgn0262245" miRNA_gene "CR33036, CR42952, 5, dme-mir-5, dme-miR-5, mir-5, miR-5" CR42952 16-Dec-15 2015_12 " embryonic stage , larval stage | first instar " "viable,visible" 1st posterior cell FBgn0262856 CG43220 http://flybase.net/reports/FBgn0262856.html protein_coding_gene DMG8-chr2L.31.003 CG43220 16-Dec-15 2015_12 FBgn0263321 CG43402 http://flybase.net/reports/FBgn0263321.html protein_coding_gene CG43402 16-Dec-15 2015_12 FBgn0013559 l(3)ry59 lethal (3) ry59 http://flybase.net/reports/FBgn0013559.html gene l(3)59 16-Dec-15 2015_12 "lethal,recessive" FBgn0005139 l(2)1542 lethal (2) 1542 http://flybase.net/reports/FBgn0005139.html gene 16-Dec-15 2015_12 "lethal,tumorigenic" "ganglion mother cell,imaginal disc,neuroblast" FBgn0065618 l(2)SH0810 lethal (2) SH0810 http://flybase.net/reports/FBgn0065618.html gene l(2)SH2 0810 16-Dec-15 2015_12 "lethal,recessive" FBgn0038214 CG9616 http://flybase.net/reports/FBgn0038214.html protein_coding_gene CG9616 16-Dec-15 2015_12 viable FBgn0037290 CG1124 http://flybase.net/reports/FBgn0037290.html protein_coding_gene 0005615=extracellular space CT1789 IPR010562=Haemolymph juvenile hormone binding CG1124 16-Dec-15 2015_12 viable FBgn0037855 CG6621 http://flybase.net/reports/FBgn0037855.html protein_coding_gene "IPR013026=Tetratricopeptide repeat-containing domain, IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain" CG6621 16-Dec-15 2015_12 ENSDARG00000013845(ttc14) ENSMUSG00000027677(Ttc14) ENSG00000163728(TTC14) viable FBgn0003417 Splotched Splotched http://flybase.net/reports/FBgn0003417.html gene Sl 16-Dec-15 2015_12 "male sterile,viable,good,male" wing hair FBgn0082194 aos::spi::vn argos::spi::vn http://flybase.net/reports/FBgn0082194.html engineered_fusion_gene argos::spi::vn 16-Dec-15 2015_12 visible anterior crossvein FBgn0039167 CG17786 http://flybase.net/reports/FBgn0039167.html protein_coding_gene CG17786 16-Dec-15 2015_12 "viable,visible" tormogen cell DRSC15270 E -0.042932761 -0.05074378 -1.618146893 -0.534345131 0.084292027 0.02986792 FBgn0019787 l(1)16 lethal (1) 16 http://flybase.net/reports/FBgn0019787.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003864 telescope telescope http://flybase.net/reports/FBgn0003864.html gene ts 16-Dec-15 2015_12 "wing,adult abdominal segment" FBgn0034549 CG18413 http://flybase.net/reports/FBgn0034549.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005257 l(3)SG77 lethal (3) SG77 http://flybase.net/reports/FBgn0005257.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0011804 l(3)rQ197 lethal (3) rQ197 http://flybase.net/reports/FBgn0011804.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003678 tdd tiddler http://flybase.net/reports/FBgn0003678.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile" FBgn0259621 B0995 http://flybase.net/reports/FBgn0259621.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing,antennal segment,leg,arista" FBgn0044064 GTD1-1.1 GTD1-1.1 http://flybase.net/reports/FBgn0044064.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000187 bis bistre http://flybase.net/reports/FBgn0000187.html gene 16-Dec-15 2015_12 FBgn0041768 anon-d36 anon-d36 http://flybase.net/reports/FBgn0041768.html gene d36 16-Dec-15 2015_12 FBgn0011822 pcl pepsinogen-like http://flybase.net/reports/FBgn0011822.html "FBgn0013391, FBgn0025377" protein_coding_gene 0004190=aspartic-type endopeptidase activity "0001737=establishment of imaginal disc-derived wing hair orientation, 0006508=proteolysis, 0016055=Wnt signaling pathway" "PCL, T2, scbeta, EG:EG0001.1, CG13374, scute beta" "IPR021109=Aspartic peptidase domain, IPR001461=Aspartic peptidase, IPR001969=Aspartic peptidase, active site" CG13374 16-Dec-15 2015_12 "ENSMUSG00000023987(Pgc),ENSMUSG00000004552(Ctse)" "ENSG00000204973,ENSG00000172647,ENSG00000180860,ENSG00000196188(CTSE),ENSG00000096088(PGC)" "lethal - all die during larval stage,recessive,planar polarity defective,somatic clone" "wing margin,somatic clone,wing hair" FBgn0035755 CG14830 http://flybase.net/reports/FBgn0035755.html protein_coding_gene CG14830 16-Dec-15 2015_12 viable DRSC08876 K 0.222560701 0.270460876 -1.482717183 0.017707489 -0.457998003 -1.550117265 FBgn0034510 CG13426 http://flybase.net/reports/FBgn0034510.html protein_coding_gene "0008565=protein transporter activity, 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity" "0006616=SRP-dependent cotranslational protein targeting to membrane, translocation" 0005784=Sec61 translocon complex "IPR001901=Protein translocase complex, SecE/Sec61-gamma subunit, IPR023391=Protein translocase SecE domain, IPR008158=Protein translocase SEC61 complex, gamma subunit, IPR022943=Preprotein translocase subunit SecE" CG13426 16-Dec-15 2015_12 YDR086C(SSS1) "viable,body color defective" mesothoracic tergum FBgn0267866 CR46154 http://flybase.net/reports/FBgn0267866.html pseudogene_attribute CR46154 16-Dec-15 2015_12 FBgn0001721 l(1)ESHS42 lethal (1) ESHS42 http://flybase.net/reports/FBgn0001721.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060890 l(3)S044626 lethal (3) S044626 http://flybase.net/reports/FBgn0060890.html FBgn0060889 gene "0446/26, l(3)S044628b, 0446/28" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038348 AOX2 Aldehyde oxidase 2 http://flybase.net/reports/FBgn0038348.html protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding, 0050660=flavin adenine dinucleotide binding, 0004031=aldehyde oxidase activity, 0016614=oxidoreductase activity, acting on CH-OH group of donors, 0009055=electron carrier activity, 0005506=iron ion binding" "0006081=cellular aldehyde metabolic process, 0055114=oxidation-reduction process" "CG18519, DmAO2" "IPR012675=Beta-grasp domain, IPR000674=Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR016166=FAD-binding, type 2, IPR002888=[2Fe-2S]-binding, IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016208=Aldehyde oxidase/xanthine dehydrogenase, IPR002346=Molybdopterin dehydrogenase, FAD-binding, IPR005107=CO dehydrogenase flavoprotein, C-terminal, IPR008274=Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding" CG18519 16-Dec-15 2015_12 FBgn0262262 mir-997-1 mir-997-1 stem loop http://flybase.net/reports/FBgn0262262.html miRNA_gene "miR-997-1, mir-997, mir-997 stem loop, miR997, miR-997, CR42969, hp-mir-997-1, dme-mir-997-1" CR42969 16-Dec-15 2015_12 viable FBgn0263522 mir-4982 mir-4982 stem loop http://flybase.net/reports/FBgn0263522.html miRNA_gene "dme-mir-4982, CR43507" CR43507 16-Dec-15 2015_12 FBgn0002719 Men Malic enzyme http://flybase.net/reports/FBgn0002719.html "FBgn0038081, FBgn0062124" protein_coding_gene "0051287=NAD binding, 0004473=malate dehydrogenase (decarboxylating) (NADP+) activity, 0004471=malate dehydrogenase (decarboxylating) (NAD+) activity" "0010941=regulation of cell death, 0008340=determination of adult lifespan, 0006108=malate metabolic process, 0030431=sleep, 0055114=oxidation-reduction process" 0005829=cytosol "malic enzyme, NADP-malic enzyme, ME, CG10120, Me, NADP-dependent malate dehydrogenase, Mdh-NADP, men, mem, anon-WO0118547.278, MDH, MEN" "IPR012301=Malic enzyme, N-terminal domain, IPR016040=NAD(P)-binding domain, IPR015884=Malic enzyme, conserved site, IPR012302=Malic enzyme, NAD-binding, IPR001891=Malic oxidoreductase" CG10120 16-Dec-15 2015_12 YKL029C(MAE1) WBGene00012983(men-1) "ENSXETG00000022647(ME1),ENSXETG00000010436(ME3),ENSXETG00000022388(Q5EC53_XENTR)" ENSMUSG00000032418(Me1) ENSG00000065833(ME1) "viable,visible,long lived,sleep defective,poor,fertile,electrophoretic variant,fast,intermediate,slow" "germline cell,male,eye" DRSC22694 I -2.491778434 -0.78040352 -0.604042791 -0.665376059 0.461028839 0.110123436 FBgn0005578 Ae Aechna http://flybase.net/reports/FBgn0005578.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" wing FBgn0017463 TfIIH-66 Transcription factor IIH-66kD http://flybase.net/reports/FBgn0017463.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TfIIH, TFIIH" 16-Dec-15 2015_12 FBgn0065855 l(2)SH0298 lethal (2) SH0298 http://flybase.net/reports/FBgn0065855.html gene l(2)SH2 0298 16-Dec-15 2015_12 "lethal,recessive" FBgn0005285 M(3)x Minute (3) x http://flybase.net/reports/FBgn0005285.html gene 16-Dec-15 2015_12 "Minute,dominant,visible" macrochaeta FBgn0002360 l(3)87Eh lethal (3) 87Eh http://flybase.net/reports/FBgn0002360.html gene "l(3)m116, m116" 16-Dec-15 2015_12 lethal FBgn0034568 CG3216 http://flybase.net/reports/FBgn0034568.html protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding, 0004383=guanylate cyclase activity, 0004872=receptor activity" "0006468=protein phosphorylation, 0006182=cGMP biosynthetic process, 0019934=cGMP-mediated signaling" 0005887=integral component of plasma membrane GYC "IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001170=Natriuretic peptide receptor, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR011645=Haem NO binding associated" CG3216 16-Dec-15 2015_12 "ENSXETG00000014291(NPR1),ENSXETG00000009854(NPR2)" viable FBgn0060861 l(3)S047716 lethal (3) S047716 http://flybase.net/reports/FBgn0060861.html gene 0477/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0011928 tRNA:M3:70Fb transfer RNA:met3:70Fb http://flybase.net/reports/FBgn0011928.html "FBgn0003814, FBgn0052144, FBgn0060144" tRNA_gene "0033436=AUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:M:CAT:AE002602-b, tRNA:met3:70Fb, tRNA[Met-ATG], CR32144, AE002602.trna23-MetCAT, chr3L.trna28-MetCAT" CR32144 16-Dec-15 2015_12 FBgn0040526 CG11602 http://flybase.net/reports/FBgn0040526.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030954 CCKLR-17D3 Cholecystokinin-like receptor at 17D3 http://flybase.net/reports/FBgn0030954.html "FBgn0030953, FBgn0044361, FBgn0046518, FBgn0046519, FBgn0052540" protein_coding_gene "0004951=cholecystokinin receptor activity, 0008188=neuropeptide receptor activity, 0015054=gastrin receptor activity, 0004930=G-protein coupled receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0008344=adult locomotory behavior" 0016021=integral component of membrane "CG6861, anon-WO0131005.21, CG32540, CG6894, DskR-1, anon-WO0170980.64, Sulfakinin receptor, CCKLR-D3, anon-WO0170980.65, DSK-receptor2, CCK-like receptor at 17D3, unnamed, DSK-R1, CG6881" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000314=Gastrin receptor, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR009126=Cholecystokinin receptor" CG32540 16-Dec-15 2015_12 ENSDARG00000052089(LOC569038) "WBGene00021439(ckr-2),WBGene00020712(ckr-1)" ENSXETG00000000911(CCKAR) "ENSMUSG00000030898(Cckbr),ENSMUSG00000029193(Cckar)" "ENSG00000163394(CCKAR),ENSG00000110148(CCKBR)" viable DRSC20015 IK 0.414043394 1.562345011 0.187170275 0.628441402 1.579028434 2.087046909 FBgn0069181 mcl(2)Z0756 mcl(2)Z0756 http://flybase.net/reports/FBgn0069181.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0043781 Burdock\pol pol http://flybase.net/reports/FBgn0043781.html transposable_element_gene "0003676=nucleic acid binding, 0004190=aspartic-type endopeptidase activity" "0015074=DNA integration, 0006508=proteolysis" "IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR021109=Aspartic peptidase domain, IPR001969=Aspartic peptidase, active site" 16-Dec-15 2015_12 FBgn0086681 Mst36Fa Male-specific transcript 36Fa http://flybase.net/reports/FBgn0086681.html "FBgn0051801, FBgn0015264, FBgn0032695" protein_coding_gene 0007283=spermatogenesis "Male-specific transcript 36Fa, CG15165, mst36Fa, CG31801" CG31801 16-Dec-15 2015_12 male semi-fertile FBgn0259553 B2012 http://flybase.net/reports/FBgn0259553.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" antennal segment FBgn0031078 Nup205 Nucleoporin 205kD http://flybase.net/reports/FBgn0031078.html FBgn0027698 protein_coding_gene 0017056=structural constituent of nuclear pore "0042332=gravitaxis, 0022008=neurogenesis, 0006999=nuclear pore organization, 0007184=SMAD protein import into nucleus, 0051297=centrosome organization" "0005737=cytoplasm, 0044611=nuclear pore inner ring" "anon-EST:Posey281, Nucleoporin 205, nup205, CG11943, Ov4" IPR021827=Nucleoporin Nup186/Nup192/Nup205 CG11943 16-Dec-15 2015_12 ENSDARG00000042530(nup205) WBGene00003789(npp-3) ENSXETG00000010597(NUP205) ENSMUSG00000038759(Nup205) ENSG00000155561(NUP205) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,gravitaxis defective" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC19432 E 0.558450567 -0.888722566 0.161035721 1.579147723 0.297141831 -0.173698284 FBgn0000788 fs(1)C4 female sterile (1) C4 http://flybase.net/reports/FBgn0000788.html gene 16-Dec-15 2015_12 female sterile "chorion,ovary" FBgn0086027 snoRNA:Or-CD1 http://flybase.net/reports/FBgn0086027.html snoRNA_gene "orphan CD1, snoRNA:OR-CD1, CR34656, DmOr_cd1" CR34656 16-Dec-15 2015_12 FBgn0030524 CG10993 http://flybase.net/reports/FBgn0030524.html FBgn0063227 protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" BcDNA:GH23064 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10993 16-Dec-15 2015_12 ENSDARG00000043666(zgc:109995) YNR054C(ESF2) WBGene00019005(F57B10.8) ENSXETG00000005684(ABT1) ENSMUSG00000036376(Abt1) ENSG00000146109(ABT1) viable FBgn0069440 E(zip)31-6 E(zip)31-6 http://flybase.net/reports/FBgn0069440.html gene 31-6 16-Dec-15 2015_12 "partially lethal - majority die,recessive,visible" leg FBgn0005750 l(1)TK303 lethal (1) TK303 http://flybase.net/reports/FBgn0005750.html gene l303 16-Dec-15 2015_12 "lethal,recessive" eye FBgn0002673 twe twine http://flybase.net/reports/FBgn0002673.html FBgn0016862 protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity" "0007348=regulation of syncytial blastoderm mitotic cell cycle, 0008315=meiotic G2/MI transition, 0006470=protein dephosphorylation, 0007283=spermatogenesis, 0000087=mitotic M phase, 0009880=embryonic pattern specification, 0051445=regulation of meiotic cell cycle, 0007140=male meiosis, 0007056=spindle assembly involved in female meiosis, 0007053=spindle assembly involved in male meiosis, 0051078=meiotic nuclear envelope disassembly" "0005634=nucleus, 0005819=spindle" "l(2)35Fh, Twine, BG:DS02740.1, cdc25, mat(2)synHB5, twn, twine, Cdc25, mat(2)syn[HB5], TWINE, Twe, mat(2)syn-A, CG4965" "IPR001763=Rhodanese-like domain, IPR000751=M-phase inducer phosphatase" CG4965 16-Dec-15 2015_12 ENSDARG00000010792(cdc25) WBGene00000386(cdc-25.1) "ENSXETG00000006710(CDC25C),ENSXETG00000012740(CDC25B),ENSXETG00000021310(cdc25a)" "ENSMUSG00000027330(Cdc25b),ENSMUSG00000044201(Cdc25c),ENSMUSG00000032477(Cdc25a)" "ENSG00000101224(CDC25B),ENSG00000158402(CDC25C),ENSG00000164045(CDC25A)" " adult stage | male , adult stage && oogenesis stage , spermatogenesis && adult stage , adult stage && oogenesis stage | stage >S6 , embryonic stage | early " " testis

, nurse cell

, oocyte

, spermatocyte

, primary spermatocyte cyst

" "meiotic cell cycle defective,viable,male sterile,recessive,visible,female fertile,mitotic cell cycle defective,wild-type,male,female,female sterile,cytokinesis defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "spermatocyte,scutellar bristle,ectopic,dorsocentral bristle,trichogen cell,tormogen cell,spindle,pole cell,maternal effect,oocyte,spindle & oocyte,spindle | embryonic stage,yolk,oocyte nucleus,spermatocyte & meiotic cell cycle" FBgn0033661 CG13185 http://flybase.net/reports/FBgn0033661.html FBgn0033660 protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" "0009267=cellular response to starvation, 0022618=ribonucleoprotein complex assembly" 0005634=nucleus CG18329 "IPR012099=Midasin, IPR011704=ATPase, dynein-related, AAA domain, IPR002035=von Willebrand factor, type A, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003593=AAA+ ATPase domain" CG13185 16-Dec-15 2015_12 YLR106C(MDN1) WBGene00018898(F55F10.1) ENSMUSG00000058006(Mdn1) ENSG00000112159(MDN1) "viable,visible" trichogen cell FBgn0029501 Crtp Caldesmon-related protein http://flybase.net/reports/FBgn0029501.html FBgn0035013 protein_coding_gene "CG13580, caldesmon-related testes protein" CG13580 16-Dec-15 2015_12 viable FBgn0051220 CG31220 http://flybase.net/reports/FBgn0051220.html FBgn0038724 protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis "c-SP6, CG16731, SP6" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG31220 16-Dec-15 2015_12 viable FBgn0001664 l(1)EA61 lethal (1) EA61 http://flybase.net/reports/FBgn0001664.html gene 16-Dec-15 2015_12 "lethal,recessive,polyphasic" FBgn0050468 Ir52c Ionotropic receptor 52c http://flybase.net/reports/FBgn0050468.html FBgn0034024 protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "IR52c, CG30468, ionotropic receptor 52c, CG12961, DmelIR52c" CG30468 16-Dec-15 2015_12 FBgn0020797 ochre ochre http://flybase.net/reports/FBgn0020797.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0267321 CR45757 http://flybase.net/reports/FBgn0267321.html non_protein_coding_gene CR45757 16-Dec-15 2015_12 FBgn0085374 CG34345 http://flybase.net/reports/FBgn0085374.html "FBgn0031838, FBgn0054009, FBgn0082894" protein_coding_gene "0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0005506=iron ion binding" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process, 0046331=lateral inhibition" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" "unnamed, CG34009, CG11053, BP1012" "IPR011990=Tetratricopeptide-like helical domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123=Oxoglutarate/iron-dependent dioxygenase" CG34345 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,wing" FBgn0004409 het-rep1 heterochromatic repeat 1 http://flybase.net/reports/FBgn0004409.html repeat_region 16-Dec-15 2015_12 FBgn0085320 CG34291 http://flybase.net/reports/FBgn0085320.html protein_coding_gene CG34291 16-Dec-15 2015_12 FBgn0014074 Tsc Triple sex combs http://flybase.net/reports/FBgn0014074.html gene 16-Dec-15 2015_12 FBgn0031764 CG9107 http://flybase.net/reports/FBgn0031764.html protein_coding_gene 0000166=nucleotide binding 0009267=cellular response to starvation Rrp7 "IPR024326=Ribosomal RNA-processing protein 7, IPR012677=Nucleotide-binding alpha-beta plait domain" CG9107 16-Dec-15 2015_12 ENSDARG00000044853(zgc:110084) WBGene00013892(ZC434.4) ENSXETG00000013414(RRP7A) "ENSMUSG00000018040(Rrp7a),ENSMUSG00000078305(Gm3436)" ENSG00000189306(RRP7A) FBgn0031515 CG9664 http://flybase.net/reports/FBgn0031515.html "FBtr0077605, FBpp0077292, FBtr0077606, FBpp0077293, FBtr0077607, FBpp0077294" protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" "0006810=transport, 0042048=olfactory behavior" 0043190=ATP-binding cassette (ABC) transporter complex "IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9664 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0050461 CG30461 http://flybase.net/reports/FBgn0050461.html "FBgn0053142, FBgn0063335, FBtr0087061, FBpp0086209, FBtr0087062, FBpp0086210, FBtr0087063, FBpp0086211, FBtr0087064, FBpp0086212, FBtr0087065, FBpp0086213, FBtr0087066, FBpp0086214" protein_coding_gene "BcDNA:AT13932, CG30461, CG33142, CR30461" CG30461 16-Dec-15 2015_12 "viable,fertile" FBgn0014214 l(2)31Bb lethal (2) 31Bb http://flybase.net/reports/FBgn0014214.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031006 rictor rapamycin-insensitive companion of Tor http://flybase.net/reports/FBgn0031006.html protein_coding_gene "0050773=regulation of dendrite development, 0051124=synaptic growth at neuromuscular junction, 0048813=dendrite morphogenesis, 0006974=cellular response to DNA damage stimulus, 0008361=regulation of cell size, 0031929=TOR signaling, 0009267=cellular response to starvation" 0031932=TORC2 complex "dRic, Rictor, CG8002, 8002, rictor, dRictor" "IPR029452=Rapamycin-insensitive companion of mTOR, domain 5, IPR029453=Rapamycin-insensitive companion of mTOR, domain 4, IPR028267=Rapamycin-insensitive companion of mTOR, N-terminal domain, IPR029451=Rapamycin-insensitive companion of mTOR, middle domain, IPR016024=Armadillo-type fold, IPR028268=Pianissimo family" CG8002 16-Dec-15 2015_12 "ENSDARG00000002020(LOC561835),ENSDARG00000059414(rictora)" YER093C(TSC11) WBGene00009245(rict-1) ENSXETG00000013215(RICTOR) ENSMUSG00000050310(Rictor) ENSG00000164327(RICTOR) "small body,viable,fertile,neuroanatomy defective,cell autonomous,somatic clone,developmental rate defective,partially lethal - majority die" "wing,class IV dendritic arborizing neuron,dendrite,cell autonomous,somatic clone,dendrite | cell autonomous | somatic clone,ventral multidendritic neuron vdaB,abdominal anterior ventral multidendritic neuron vdaa,dorsal multidendritic neuron ddaC,embryonic/larval neuromuscular junction" FBgn0086378 Alg-2 Apoptosis-linked gene-2 http://flybase.net/reports/FBgn0086378.html "FBgn0039995, FBgn0065036, FBgn0058410" protein_coding_gene 0005509=calcium ion binding "0046330=positive regulation of JNK cascade, 0006915=apoptotic process" "CG17661, ALG-2, Apoptosis-linked gene-2, apoptosis-linked gene-2, DALG-2, CG40410" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG40410 16-Dec-15 2015_12 ENSDARG00000005220(pdcd6) WBGene00019770(M04F3.4) ENSXETG00000027021(pdcd6) ENSMUSG00000021576(Pdcd6) FBgn0012025 tRNA:Y1:85Ab transfer RNA:tyr1:85Ab http://flybase.net/reports/FBgn0012025.html "FBgn0003849, FBgn0012014, FBgn0051433, FBgn0060004" tRNA_gene "0033410=UAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3R.trna64-TyrGTA, tRNA[Tyr], tRNA:Y, tRNA:Y:GTA:AE002708-b, tRNA[Tyr][[1gamma]], CR31433, Tyr-tRNA T85b, AE002708.trna58-TyrGTA, tRNA-Tyr, tRNA:tyr1:85Ab, 85Ab" CR31433 16-Dec-15 2015_12 FBgn0038486 CG5265 http://flybase.net/reports/FBgn0038486.html protein_coding_gene 0004092=carnitine O-acetyltransferase activity "0006631=fatty acid metabolic process, 0009437=carnitine metabolic process" "0005743=mitochondrial inner membrane, 0005783=endoplasmic reticulum, 0005777=peroxisome" IPR000542=Acyltransferase ChoActase/COT/CPT CG5265 16-Dec-15 2015_12 "ENSDARG00000040248(crata),ENSDARG00000016545(zgc:154046),ENSDARG00000010382(LOC100334862)" YML042W(CAT2) WBGene00007175(B0395.3) "ENSXETG00000018965(crat),ENSXETG00000005161()" ENSMUSG00000026853(Crat) ENSG00000095321(CRAT) "viable,visible" mesothoracic tergum FBgn0043562 Su(hh)V Su(hh)V http://flybase.net/reports/FBgn0043562.html gene 16-Dec-15 2015_12 FBgn0050098 CG30098 http://flybase.net/reports/FBgn0050098.html "FBtr0087168, FBpp0086312" protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0050830=defense response to Gram-positive bacterium" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG30098 16-Dec-15 2015_12 FBgn0027378 MRG15 MORF-related gene 15 http://flybase.net/reports/FBgn0027378.html FBgn0024526 protein_coding_gene "0035064=methylated histone binding, 0005515=protein binding" "0051276=chromosome organization, 0006342=chromatin silencing, 0051304=chromosome separation, 0016573=histone acetylation, 0043486=histone exchange" "0005634=nucleus, 0000123=histone acetyltransferase complex, 0035267=NuA4 histone acetyltransferase complex" "MRG15, dMRG15, Dmrg15, Mrg15, l(3)j6A3, dMrg15, CG6363, DmMRG15" "IPR025995=RNA binding activity-knot of a chromodomain, IPR008676=MRG, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like, IPR026541=MRG domain" CG6363 16-Dec-15 2015_12 ENSDARG00000041155(morf4l1) YPR023C(EAF3) WBGene00003406(mrg-1) ENSXETG00000007837(morf4l1) "ENSMUSG00000043223(Gm4835),ENSMUSG00000062270(Morf4l1),ENSMUSG00000031422(Morf4l2)" "ENSG00000185787(MORF4L1),ENSG00000123562(MORF4L2)" "female semi-sterile,short lived,lethal,recessive,suppressor of variegation,dominant,viable,non-suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,male limited" FBgn0050094 CG30094 http://flybase.net/reports/FBgn0050094.html "FBgn0034080, FBgn0064778" protein_coding_gene 0008270=zinc ion binding "CG15700, BcDNA:SD13256" "IPR000058=Zinc finger, AN1-type" CG30094 16-Dec-15 2015_12 "viable,fertile" FBgn0262023 CG42834 http://flybase.net/reports/FBgn0262023.html protein_coding_gene CG42834 16-Dec-15 2015_12 FBgn0041598 l(2)Ia lethal (2) Ia http://flybase.net/reports/FBgn0041598.html gene unnamed 16-Dec-15 2015_12 FBgn0022284 l(2)IR12 lethal (2) IR12 http://flybase.net/reports/FBgn0022284.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039109 CG10365 http://flybase.net/reports/FBgn0039109.html FBgn0062048 protein_coding_gene anon-WO0118547.386 "IPR006840=ChaC-like protein, IPR013024=Butirosin biosynthesis, BtrG-like" CG10365 16-Dec-15 2015_12 ENSDARG00000070426(chac1) WBGene00017724(F22F7.7) ENSXETG00000021601(CHAC1) ENSMUSG00000027313(Chac1) ENSG00000128965(CHAC1) viable FBgn0037630 Ir85a Ionotropic receptor 85a http://flybase.net/reports/FBgn0037630.html protein_coding_gene "0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" 0009593=detection of chemical stimulus "0016021=integral component of membrane, 0016020=membrane" "ionotropic receptor 85a, CT32618, CG11775, IR85a, DmelIR85a" IPR001320=Ionotropic glutamate receptor CG11775 16-Dec-15 2015_12 viable FBgn0005074 fs(2)OW215 female sterile (2) OW215 http://flybase.net/reports/FBgn0005074.html gene 16-Dec-15 2015_12 FBgn0030507 CG11164 http://flybase.net/reports/FBgn0030507.html protein_coding_gene 0005634=nucleus "IPR019024=Ribonuclease H2, subunit B" CG11164 16-Dec-15 2015_12 "ENSDARG00000067526,ENSDARG00000005128(rnaseh2b)" WBGene00009011(F21D5.6) ENSXETG00000020720(TEgg013b21.1) ENSMUSG00000021932(Rnaseh2b) ENSG00000136104(RNASEH2B) "viable,fertile" DRSC19392 K 0.008772921 0.034548103 -0.264672176 0.299891017 -0.509876431 1.507405748 FBgn0264978 Slh SLY-1 homologous http://flybase.net/reports/FBgn0264978.html "FBgn0015816, FBgn0031429" protein_coding_gene 0000149=SNARE binding "0006904=vesicle docking involved in exocytosis, 0006909=phagocytosis, 0006605=protein targeting, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0048190=wing disc dorsal/ventral pattern formation, 0000902=cell morphogenesis, 0022008=neurogenesis" 0031201=SNARE complex "SLY1, CG15393, slh, d-sly, Sly, CG3539, Sly1p, Sly1, SLY1 homologous" "IPR001619=Sec1-like protein, IPR027482=Sec1-like, domain 2" CG3539 16-Dec-15 2015_12 ENSDARG00000000779(sly1) YDR189W(SLY1) WBGene00009654(F43D9.3) ENSXETG00000014165() ENSMUSG00000020952(Scfd1) ENSG00000092108(SCFD1) embryonic stage | stage >=14 " embryonic/larval salivary gland

, embryonic/larval esophagus

, embryonic/larval midgut | posterior

" DRSC00789 IE 0.172701001 2.255084099 2.910395869 -1.364833688 -0.391035765 0.648986177 FBgn0041832 Eth-AR315 Eth-AR315 http://flybase.net/reports/FBgn0041832.html gene Eth[AR]315 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0053530 Acp53C14c Accessory gland protein 53C14c http://flybase.net/reports/FBgn0053530.html FBgn0070033 protein_coding_gene 0032504=multicellular organism reproduction "0005615=extracellular space, 0005576=extracellular region" "CG33530, HDC06801, Acp53C14c" IPR009392=Drosophila ACP53EA CG33530 16-Dec-15 2015_12 FBgn0029723 Proc-R Proctolin receptor http://flybase.net/reports/FBgn0029723.html "FBgn0046511, FBgn0046512" protein_coding_gene "0035236=proctolin receptor activity, 0004930=G-protein coupled receptor activity, 0008528=G-protein coupled peptide receptor activity, 0008188=neuropeptide receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "anon-WO0170980.73, anon-WO0170980.74, ProcR, proctolin receptor, CG6986, Proc R, Proc-R" "IPR019427=7TM GPCR, serpentine receptor class w (Srw), IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG6986 16-Dec-15 2015_12 adult stage head

viable FBgn0266144 CR44850 http://flybase.net/reports/FBgn0266144.html non_protein_coding_gene CR44850 16-Dec-15 2015_12 FBgn0267587 CR45925 http://flybase.net/reports/FBgn0267587.html non_protein_coding_gene CR45925 16-Dec-15 2015_12 FBgn0065808 l(2)SH0389 lethal (2) SH0389 http://flybase.net/reports/FBgn0065808.html gene l(2)SH2 0389 16-Dec-15 2015_12 "lethal,recessive" FBgn0003030 patulous patulous http://flybase.net/reports/FBgn0003030.html gene pa 16-Dec-15 2015_12 "visible,viable,fertile,partially" wing FBgn0037296 Prosë_2R2 Proteasome ë_2 subunit-related 2 http://flybase.net/reports/FBgn0037296.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0019774=proteasome core complex, beta-subunit complex, 0005839=proteasome core complex" "beta2R2, Proteasome beta2R2 subunit, CG12161" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR023333=Proteasome B-type subunit, IPR000243=Peptidase T1A, proteasome beta-subunit, IPR001353=Proteasome, subunit alpha/beta" CG12161 16-Dec-15 2015_12 viable FBgn0014395 tilB touch insensitive larva B http://flybase.net/reports/FBgn0014395.html FBgn0031185 protein_coding_gene "0045433=male courtship behavior, veined wing generated song production, 0010378=temperature compensation of the circadian clock, 0035082=axoneme assembly, 0007605=sensory perception of sound" 0005737=cytoplasm "CG14620, TilB, touch-insensitive-larva-B, touch insensitive larvaeB" "IPR001611=Leucine-rich repeat, IPR003603=U2A'/phosphoprotein 32 family A, C-terminal" CG14620 16-Dec-15 2015_12 ENSDARG00000053318(lrrc6) ENSXETG00000023039(lrrc6) ENSMUSG00000022375(Lrrc6) ENSG00000129295(LRRC6) "locomotor behavior defective,locomotor rhythm defective,touch sensitivity defective,recessive,behavior defective,courtship behavior defective,auditory perception defective,male sterile,song defective,neuroanatomy defective,viable" "adult antennal nerve,spermatid axoneme,arista,cilium,scolopidial cilium,Johnston organ" FBgn0025186 ari-2 ariadne 2 http://flybase.net/reports/FBgn0025186.html FBgn0010640 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0003676=nucleic acid binding, 0008270=zinc ion binding" 0000209=protein polyubiquitination 0005737=cytoplasm "ari2, CG5709, ariadne-2, l(2)07768, AAF46823.1" "IPR001878=Zinc finger, CCHC-type, IPR031127=E3 ubiquitin ligase RBR family, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR031126=E3 ubiquitin-protein ligase ARIH2, IPR002867=IBR domain" CG5709 16-Dec-15 2015_12 ENSDARG00000012848(arih2) YKR017C() WBGene00020462(T12E12.1) ENSXETG00000024753(Arih2) ENSMUSG00000064145(Arih2) ENSG00000177479(ARIH2) "viable,fertile,lethal,recessive,neuroanatomy defective,somatic clone,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "neuroblast,somatic clone" DRSC04672 IEK -0.236320795 1.881179688 2.457436611 0.652991621 2.463064756 -0.143321998 FBgn0000868 fs(1)M63 female sterile (1) M63 http://flybase.net/reports/FBgn0000868.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0011442 l(3)j13E7 lethal (3) j13E7 http://flybase.net/reports/FBgn0011442.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037411 Osi3 Osiris 3 http://flybase.net/reports/FBgn0037411.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG1150, osi3" IPR012464=Protein of unknown function DUF1676 CG1150 16-Dec-15 2015_12 viable FBgn0267742 CR46073 http://flybase.net/reports/FBgn0267742.html non_protein_coding_gene CR46073 16-Dec-15 2015_12 FBgn0259617 B1510 http://flybase.net/reports/FBgn0259617.html gene 16-Dec-15 2015_12 visible tarsal segment FBgn0026347 Su(dalyh)26H6 Su(dalyh)26H6 http://flybase.net/reports/FBgn0026347.html gene "Su(lyh), Su(da[lyh])" 16-Dec-15 2015_12 wild-type FBgn0025346 anon-11c anon-11c http://flybase.net/reports/FBgn0025346.html gene 16-Dec-15 2015_12 FBgn0022143 l(2)k06113 lethal (2) k06113 http://flybase.net/reports/FBgn0022143.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051901 Mur29B Mucin related 29B http://flybase.net/reports/FBgn0051901.html FBgn0063097 protein_coding_gene 0005201=extracellular matrix structural constituent 0031012=extracellular matrix "CG31901, Mur29B, BcDNA:LP08232" CG31901 16-Dec-15 2015_12 "viable,fertile" FBgn0011832 Ser12 Serine protease 12 http://flybase.net/reports/FBgn0011832.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0004185=serine-type carboxypeptidase activity" "0006508=proteolysis, 0042060=wound healing" "CG17240, SP92" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG17240 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" viable DRSC00786 K 0.372886302 0.164008239 -0.227467698 0.426881724 -0.846291776 -2.227627711 FBgn0039080 Ir94h Ionotropic receptor 94h http://flybase.net/reports/FBgn0039080.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG17382, DmelIR94h, ionotropic receptor 94h, IR94h" CG17382 16-Dec-15 2015_12 viable FBgn0030298 Or10a Odorant receptor 10a http://flybase.net/reports/FBgn0030298.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "DOR92, CG17867, 10B.1, odorant receptor 10a, 10a" "IPR004117=Olfactory receptor, Drosophila" CG17867 16-Dec-15 2015_12 "viable,fertile,taste perception defective" FBgn0260446 GABA-B-R1 metabotropic GABA-B receptor subtype 1 http://flybase.net/reports/FBgn0260446.html "FBgn0028924, FBgn0032558, FBgn0046567, FBgn0046568" protein_coding_gene "0046982=protein heterodimerization activity, 0004965=G-protein coupled GABA receptor activity" "0007194=negative regulation of adenylate cyclase activity, 0007214=gamma-aminobutyric acid signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0038039=G-protein coupled receptor heterodimeric complex, 0016021=integral component of membrane" "GABA[[B]]R, D-GABA[[B]]R1, GABA[[B]], GABA(B)R1, anon-WO0170980.176, CG15274, D-Gaba1, GB1, GABA[[B]]R1, BG:DS00929.6, anon-WO0170980.175" "IPR017978=GPCR, family 3, C-terminal, IPR002455=GPCR, family 3, gamma-aminobutyric acid receptor, type B, IPR002456=GPCR, family 3, gamma-aminobutyric acid receptor, type B1, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I" CG15274 16-Dec-15 2015_12 FBgn0263658 CR43649 http://flybase.net/reports/FBgn0263658.html non_protein_coding_gene CR43649 16-Dec-15 2015_12 FBgn0026358 Su(SuRaf1)1 Su(SuRaf1)1 http://flybase.net/reports/FBgn0026358.html gene Su[Su(Raf)1]1 16-Dec-15 2015_12 "lethal,recessive" FBgn0004816 fs(2)ltoRU26 female sterile (2) ltoRU26 http://flybase.net/reports/FBgn0004816.html gene 0007304=chorion-containing eggshell formation Ru26 16-Dec-15 2015_12 female sterile FBgn0260861 Trs23 TRAPP subunit 23 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0260861.html "FBgn0044806, FBgn0032060" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0006888=ER to Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport" "0005801=cis-Golgi network, 0030008=TRAPP complex" "Trs23, CG9298, TRS23, Trs23p" "IPR011012=Longin-like domain, IPR007233=Sybindin-like protein" CG9298 16-Dec-15 2015_12 ENSDARG00000027418(trappc4) YDR246W(TRS23) WBGene00018088(F36D4.2) ENSXETG00000010072(TRAPPC4) ENSMUSG00000032112(Trappc4) ENSG00000196655(TRAPPC4) DRSC03190 I 0.38319755 1.59979925 1.234167473 0.470031792 -0.230695005 0.632184629 FBgn0053390 5SrRNA:CR33390 5SrRNA:CR33390 http://flybase.net/reports/FBgn0053390.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33390 CR33390 16-Dec-15 2015_12 FBgn0086385 BG01563 http://flybase.net/reports/FBgn0086385.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0016922 put::tor put::tor http://flybase.net/reports/FBgn0016922.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0016770 anon-47Aa anon-47Aa http://flybase.net/reports/FBgn0016770.html gene 16-Dec-15 2015_12 FBgn0025480 ms(3)nc14 male sterile (3) noncomplementer 14 http://flybase.net/reports/FBgn0025480.html gene 16-Dec-15 2015_12 male sterile FBgn0024658 l(2)k07620 lethal (2) k07620 http://flybase.net/reports/FBgn0024658.html gene 76/20 16-Dec-15 2015_12 "visible,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,wing,trichome" FBgn0035429 CG12017 http://flybase.net/reports/FBgn0035429.html protein_coding_gene CG12017 16-Dec-15 2015_12 viable FBgn0004206 l(3)84Ed lethal (3) 84Ed http://flybase.net/reports/FBgn0004206.html gene 16-Dec-15 2015_12 lethal FBgn0053834 His1:CG33834 His1:CG33834 http://flybase.net/reports/FBgn0053834.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33834 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5" CG33834 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0030941 wgn wengen http://flybase.net/reports/FBgn0030941.html FBgn0062834 protein_coding_gene "0005515=protein binding, 0005031=tumor necrosis factor-activated receptor activity" "0070050=neuron cellular homeostasis, 0006915=apoptotic process, 1900074=negative regulation of neuromuscular synaptic transmission, 0072499=photoreceptor cell axon guidance, 0007166=cell surface receptor signaling pathway" 0005887=integral component of plasma membrane "TNFR, TNF-alpha receptor, vader, Wengen, CG6531, Wgn" IPR001368=TNFR/NGFR cysteine-rich region CG6531 16-Dec-15 2015_12 "neuroanatomy defective,somatic clone,viable,fertile" "lamina,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,somatic clone,lamina plexus | third instar larval stage,medulla | third instar larval stage,lamina plexus,cell non-autonomous | third instar larval stage,cell autonomous | third instar larval stage" FBgn0022317 l(1)D10.2 lethal (1) D10.2 http://flybase.net/reports/FBgn0022317.html gene D10.2 16-Dec-15 2015_12 "lethal,recessive" FBgn0037546 mAChR-B "muscarinic Acetylcholine Receptor, B-type" http://flybase.net/reports/FBgn0037546.html "FBgn0046498, FBgn0046499" protein_coding_gene "0016907=G-protein coupled acetylcholine receptor activity, 0008227=G-protein coupled amine receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.92, mAChR B, mAcR-CG7918, anon-WO0170980.91, B-type mAChR, Dm-mAChR-B, CG7918" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG7918 16-Dec-15 2015_12 WBGene00001518(gar-2) DRSC16345 IE 0.384868772 -2.627452625 -0.649298535 -4.683847635 1.055493342 1.212806216 FBgn0029088 disp dispatched http://flybase.net/reports/FBgn0029088.html FBgn0037390 protein_coding_gene 0008158=hedgehog receptor activity "0007224=smoothened signaling pathway, 0007280=pole cell migration, 0006887=exocytosis" "0016020=membrane, 0016021=integral component of membrane" "Dispatched, CG2019, anon-WO0146227.1, Disp" "IPR030223=Protein dispatched, IPR000731=Sterol-sensing domain, IPR003392=Patched" CG2019 16-Dec-15 2015_12 "ENSDARG00000044417(disp1),ENSDARG00000042846(disp2)" WBGene00004211(ptd-2) "ENSXETG00000015029(DISP1),ENSXETG00000013393(DISP2)" "ENSMUSG00000030768,ENSMUSG00000040035(Disp2)" "ENSG00000154309(DISP1),ENSG00000140323(DISP2)" " larval stage , embryonic stage " " dorsal mesothoracic disc | ubiquitous

, embryo | ubiquitous

" "lethal,recessive,rescuable maternal effect,segment polarity phenotype,wild-type,visible,somatic clone,viable" "denticle,germline clone,maternal effect,embryonic/first instar larval cuticle,denticle belt,ventral,wing,somatic clone,1st posterior cell,eye" FBgn0020571 anon-85Ca anon-85Ca http://flybase.net/reports/FBgn0020571.html gene "2.2kb, unnamed" 16-Dec-15 2015_12 FBgn0030269 CDK2AP1 CDK2-associated protein 1 http://flybase.net/reports/FBgn0030269.html FBgn0066847 protein_coding_gene "anon-WO03040301.144, CDK2AP1, DOC1, CDK2-associated protein 1, CG18292, Deleted in oral cancer 1" IPR019187=Cyclin-dependent kinase 2-associated protein CG18292 16-Dec-15 2015_12 "ENSG00000111328(CDK2AP1),ENSG00000167797(CDK2AP2)" FBgn0002843 msc melanoscutellum http://flybase.net/reports/FBgn0002843.html gene ms 16-Dec-15 2015_12 "viable,fertile,visible,recessive,body color defective" "scutellum,macrochaeta & adult thorax,scutellar bristle,eye,wing" FBgn0060334 l(3)S144812 lethal (3) S144812 http://flybase.net/reports/FBgn0060334.html gene 1448/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0035495 CG14989 http://flybase.net/reports/FBgn0035495.html FBgn0064973 protein_coding_gene BcDNA:GH06302 CG14989 16-Dec-15 2015_12 viable DRSC25585 K 0.225219301 0.252159666 -0.326452191 0.849593942 2.296285827 0.197026145 FBgn0035513 Cpr64Ad Cuticular protein 64Ad http://flybase.net/reports/FBgn0035513.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development "0031012=extracellular matrix, 0005811=lipid particle" "CG1259, DmelCpr64Ad" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG1259 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0067676 nain nain http://flybase.net/reports/FBgn0067676.html gene 0001555=oocyte growth 16-Dec-15 2015_12 lethal "oocyte,germline clone" FBgn0021902 l(2)k12402 lethal (2) k12402 http://flybase.net/reports/FBgn0021902.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027205 l(1)G0398 lethal (1) G0398 http://flybase.net/reports/FBgn0027205.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033961 ND-B15 NADH dehydrogenase (ubiquinone) B15 subunit http://flybase.net/reports/FBgn0033961.html FBgn0025196 protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "anon-fast-evolving-3B12, CG 12859, NADH-ubiquinone oxidoreductase B15 subunit, NADH:ubiquinone oxidoreductase B15 subunit, NB5M, anon-EST:fe3B12, unnamed, NADH ubiquinone oxidoreductase B15, CG12859" "IPR009866=NADH:ubiquinone oxidoreductase, subunit NDUFB4" CG12859 16-Dec-15 2015_12 ENSDARG00000019332(ndufb4) "ENSG00000124399,ENSG00000065518(NDUFB4),ENSG00000215727" "lethal,visible" trichogen cell FBgn0046837 l(3)A4-4L7 lethal (3) A4-4L7 http://flybase.net/reports/FBgn0046837.html gene 16-Dec-15 2015_12 lethal FBgn0037191 CG14448 http://flybase.net/reports/FBgn0037191.html protein_coding_gene CG14448 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0024253 ami anosmic http://flybase.net/reports/FBgn0024253.html gene 0007635=chemosensory behavior 16-Dec-15 2015_12 smell perception defective FBgn0037069 Cpr78Cc Cuticular protein 78Cc http://flybase.net/reports/FBgn0037069.html "FBgn0026291, FBgn0063036" protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr78Cc, BcDNA:RE32113, CG7658, anon-EST:ParkEST167" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG7658 16-Dec-15 2015_12 viable FBgn0022026 l(2)k08914 lethal (2) k08914 http://flybase.net/reports/FBgn0022026.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266636 CR45143 http://flybase.net/reports/FBgn0266636.html non_protein_coding_gene CR45143 16-Dec-15 2015_12 FBgn0032955 CG2201 http://flybase.net/reports/FBgn0032955.html "FBtr0085921, FBpp0085275, FBtr0085922, FBpp0085276, FBtr0085923, FBpp0085277" protein_coding_gene "0004103=choline kinase activity, 0004305=ethanolamine kinase activity" "0016310=phosphorylation, 0006656=phosphatidylcholine biosynthetic process, 0006646=phosphatidylethanolamine biosynthetic process" 0005737=cytoplasm "IPR011009=Protein kinase-like domain, IPR026712=Choline/Ethanolamine kinase" CG2201 16-Dec-15 2015_12 "ENSDARG00000041078(chka),ENSDARG00000063167(chkb)" "YLR133W(CKI1),YDR147W(EKI1)" "WBGene00000509(cka-1),WBGene00000510(cka-2)" ENSXETG00000010020(chka) "ENSMUSG00000024843(Chka),ENSMUSG00000022617(Chkb)" "ENSG00000100288(CHKB),ENSG00000110721(CHKA)" viable FBgn0060365 l(3)S138307 lethal (3) S138307 http://flybase.net/reports/FBgn0060365.html gene 1383/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266910 CR45370 http://flybase.net/reports/FBgn0266910.html non_protein_coding_gene CR45370 16-Dec-15 2015_12 FBgn0266255 CR44950 http://flybase.net/reports/FBgn0266255.html non_protein_coding_gene lincRNA.857 CR44950 16-Dec-15 2015_12 FBgn0020589 anon-57Ch anon-57Ch http://flybase.net/reports/FBgn0020589.html gene unnamed 16-Dec-15 2015_12 FBgn0005009 dil(wa) dilutor of white-apricot http://flybase.net/reports/FBgn0005009.html gene dil-w[a] 16-Dec-15 2015_12 eye color defective pigment cell FBgn0036154 CG6168 http://flybase.net/reports/FBgn0036154.html protein_coding_gene 0004222=metalloendopeptidase activity "0050829=defense response to Gram-negative bacterium, 0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space IPR007484=Peptidase M28 CG6168 16-Dec-15 2015_12 "ENSDARG00000060776,ENSDARG00000061691(si:dkey-149j18.2),ENSDARG00000062293(LOC564655)" YFR018C() viable FBgn0005425 l(1)adl14 lethal (1) adl14 http://flybase.net/reports/FBgn0005425.html gene l(1)adl-14 16-Dec-15 2015_12 "lethal,heat sensitive,short lived" FBgn0264513 CR43912 http://flybase.net/reports/FBgn0264513.html non_protein_coding_gene "lincRNA.539, lincRNA.538" CR43912 16-Dec-15 2015_12 FBgn0039600 CG1646 http://flybase.net/reports/FBgn0039600.html protein_coding_gene "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0005685=U1 snRNP" Prp39 "IPR001623=DnaJ domain, IPR003107=HAT (Half-A-TPR) repeat, IPR011990=Tetratricopeptide-like helical domain" CG1646 16-Dec-15 2015_12 ENSDARG00000042080(prpf39) WBGene00017768(F25B4.5) ENSXETG00000003066(PRPF39) ENSMUSG00000035597(Prpf39) ENSG00000185246(PRPF39) viable FBgn0013621 l(3)neo11 lethal (3) neo11 http://flybase.net/reports/FBgn0013621.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016694 Pdp1 PAR-domain protein 1 http://flybase.net/reports/FBgn0016694.html "FBgn0035820, FBgn0044667" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0042803=protein homodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0019216=regulation of lipid metabolic process, 0040007=growth, 0042023=DNA endoreduplication, 0045893=positive regulation of transcription, DNA-templated, 0007584=response to nutrient, 0007623=circadian rhythm, 0007067=mitotic nuclear division" 0005634=nucleus "PDP1, Pdp1e, PDP1epsilon, DM1, pdp1epsilon, PAR domain protein 1, pdp1, PAR-protein domain1, anon-WO0140519.206, PAR-DOMAIN-PROTEIN 1, PAR-domain protein 1, Pdp1 epsilon, PAR DOMAIN PROTEIN 1, PAR-Domain Protein 1, CG17888, Par domain protein 1epsilon, Pdp-1, PAR domain protein 1epsilon, DM32, PDP, Par domain protein 1, PAR Domain Protein 1, Pdp1epsilon, par domain protein 1, pdp, mel_pdp1" IPR004827=Basic-leucine zipper domain CG17888 16-Dec-15 2015_12 "ENSXETG00000003160(DBP),ENSXETG00000004316(HLF)" "ENSMUSG00000022389(Tef),ENSMUSG00000003949(Hlf),ENSMUSG00000059824(Dbp)" "ENSG00000167074(TEF),ENSG00000108924(HLF),ENSG00000105516(DBP)" "viable,fertile,circadian behavior defective,recessive,developmental rate defective,lethal,small body,mitotic cell cycle defective,cell non-autonomous,lethal - all die before end of larval stage,some die during larval stage" DRSC08897 K -1.676708196 -0.556742061 FBgn0022309 l(1)K84.3 lethal (1) K84.3 http://flybase.net/reports/FBgn0022309.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030177 CG2972 http://flybase.net/reports/FBgn0030177.html protein_coding_gene 0004521=endoribonuclease activity "0042274=ribosomal small subunit biogenesis, 0022008=neurogenesis, 0000469=cleavage involved in rRNA processing, 0009267=cellular response to starvation" "IPR014881=Nin one binding (NOB1) Zn-ribbon-like, IPR017117=D-site 20S pre-rRNA nuclease Nob1" CG2972 16-Dec-15 2015_12 ENSDARG00000016080(wu:fc27e05) YOR056C(NOB1) WBGene00021843(Y54E10BR.4) ENSXETG00000017874(TEgg058p21.1) ENSMUSG00000003848(Nob1) ENSG00000141101(NOB1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0039042 CG13837 http://flybase.net/reports/FBgn0039042.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13837 16-Dec-15 2015_12 viable FBgn0083041 snoRNA:ë¬18S-1854b snoRNA:ë¬18S-1854b http://flybase.net/reports/FBgn0083041.html snoRNA_gene "Psi18S-1854b, chrX:16979518..16979650, CR34600, psi18S-1854b" CR34600 16-Dec-15 2015_12 FBgn0000701 fltG flight defective G http://flybase.net/reports/FBgn0000701.html gene 16-Dec-15 2015_12 flight defective FBgn0031194 CG17598 http://flybase.net/reports/FBgn0031194.html protein_coding_gene "0043169=cation binding, 0004721=phosphoprotein phosphatase activity, 0004722=protein serine/threonine phosphatase activity" "0016311=dephosphorylation, 0006470=protein dephosphorylation" "0005634=nucleus, 0005737=cytoplasm" PP2C "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C, IPR000222=PPM-type phosphatase, divalent cation binding" CG17598 16-Dec-15 2015_12 ENSDARG00000063684(zgc:153678) WBGene00016580(C42C1.2) ENSXETG00000017214(BC075345.1) "ENSMUSG00000034613(Ppm1h),ENSMUSG00000002228(Ppm1j)" "ENSG00000111110(PPM1H),ENSG00000155367(PPM1J)" viable DRSC20636 K -0.11600613 -0.720911304 -0.241919384 -0.403741787 1.70573182 -0.339971052 FBgn0038708 CG6255 http://flybase.net/reports/FBgn0038708.html FBgn0044678 protein_coding_gene "0004776=succinate-CoA ligase (GDP-forming) activity, 0048037=cofactor binding" "0046331=lateral inhibition, 0008152=metabolic process" 0045244=succinate-CoA ligase complex (GDP-forming) "anon-WO0140519.197, AAF55672" "IPR017440=ATP-citrate lyase/succinyl-CoA ligase, active site, IPR016102=Succinyl-CoA synthetase-like, IPR005810=Succinyl-CoA ligase, alpha subunit, IPR005811=ATP-citrate lyase/succinyl-CoA ligase, IPR016040=NAD(P)-binding domain, IPR003781=CoA-binding" CG6255 16-Dec-15 2015_12 YOR142W(LSC1) "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0266599 Hsc70-4 Heat shock protein cognate 4 http://flybase.net/reports/FBgn0266599.html "FBgn0001219, FBgn0010802, FBgn0011400, FBgn0024549, FBgn0062154, FBgn0066308" protein_coding_gene "0016887=ATPase activity, 0051082=unfolded protein binding, 0051087=chaperone binding" "0007269=neurotransmitter secretion, 0000398=mRNA splicing, via spliceosome, 0001700=embryonic development via the syncytial blastoderm, 0016246=RNA interference, 0016192=vesicle-mediated transport, 0007413=axonal fasciculation, 0007399=nervous system development, 0006457=protein folding, 0035967=cellular response to topologically incorrect protein, 0007411=axon guidance" "0030018=Z disc, 0005875=microtubule associated complex, 0071013=catalytic step 2 spliceosome, 0005743=mitochondrial inner membrane, 0005811=lipid particle, 0005726=perichromatin fibrils, 0071011=precatalytic spliceosome, 0005739=mitochondrion, 0005737=cytoplasm, 0005634=nucleus" "Hsc70, hsc4, scattered, BAP74, hsp cognate 4, E(nd)195, l(3)L3929, Bap74, HSC70, heat shock cognate 70, hsc70-4, chr3R:11070155..11070315, mtHsp 70, Hsp cognate 4, bs17d06.y1, CG4264, hsc70, HSC-70, heat shock cognate 4, Heat shock 70-kDa protein cognate 4, Heat shock protein 70, hsp70, dhsc70, scd, l(3)j7A4, Hsp-c4, Heat shock cognate 4, Q3KN45_DROME, HSC4, Hsc-70-4, Hsc4p, HSC70-4, anon-WO0118547.237, Hsc4, heat-shock protein 70, l(3)03550, i190, Hsc-4, heat shock cognate protein 4, Hsp70, heat shock cognate protein 70-4, E(csp)1545" "IPR013126=Heat shock protein 70 family, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site, IPR029047=Heat shock protein 70kD, peptide-binding domain" CG4264 16-Dec-15 2015_12 "ENSDARG00000068992(hspa8),ENSDARG00000037403,ENSDARG00000012381(zgc:63663)" "YBL075C(SSA3),YAL005C(SSA1),YLL024C(SSA2),YER103W(SSA4)" WBGene00002005(hsp-1) "ENSXETG00000013038(HSPA8),ENSXETG00000004097()" "ENSMUSG00000015656(Hspa8),ENSMUSG00000059814" ENSG00000109971(HSPA8) DRSC16711 E 0.296934844 -0.719750652 -4.781154456 -1.760949267 1.133715354 0.518721172 FBgn0004918 spk spike http://flybase.net/reports/FBgn0004918.html gene 0003729=mRNA binding 0007602=phototransduction 16-Dec-15 2015_12 FBgn0261631 CG42714 http://flybase.net/reports/FBgn0261631.html protein_coding_gene DMG8-chr3L.11.020 CG42714 16-Dec-15 2015_12 FBgn0002597 M(2)31A Minute (2) 31A http://flybase.net/reports/FBgn0002597.html gene "M(2)S11, M(2)t, M(2)LS3, M(2)fs, M[[e]], M(2)e, M(2)30A" 16-Dec-15 2015_12 "Minute,dominant,visible,developmental rate defective,female sterile" "macrochaeta,ovary,adult abdomen" FBgn0034255 Oxp Oxpecker http://flybase.net/reports/FBgn0034255.html protein_coding_gene 0003682=chromatin binding 0051276=chromosome organization 0000785=chromatin "CG18186, OXP, Oxpecker" "IPR023780=Chromo domain, IPR017984=Chromo domain subgroup, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like" CG18186 16-Dec-15 2015_12 viable FBgn0002594 M(2)24D Minute (2) 24D http://flybase.net/reports/FBgn0002594.html gene "l(2)24Db, M(2)LS2" 16-Dec-15 2015_12 FBgn0065946 l(2)SH0105 lethal (2) SH0105 http://flybase.net/reports/FBgn0065946.html gene l(2)SH2 0105 16-Dec-15 2015_12 "lethal,recessive" FBgn0062697 EP1154 EP1154 http://flybase.net/reports/FBgn0062697.html gene EP(3)1154 16-Dec-15 2015_12 FBgn0005143 l(2)DTS1 lethal (2) DTS1 http://flybase.net/reports/FBgn0005143.html gene 16-Dec-15 2015_12 "lethal,dominant,heat sensitive" FBgn0016924 rope rope http://flybase.net/reports/FBgn0016924.html gene 16-Dec-15 2015_12 FBgn0052112 CG32112 http://flybase.net/reports/FBgn0052112.html FBgn0036304 protein_coding_gene CG10982 "IPR029058=Alpha/Beta hydrolase fold, IPR019149=Protein of unknown function DUF2048" CG32112 16-Dec-15 2015_12 ENSDARG00000029975(zgc:110741) WBGene00008317(C54G4.7) ENSXETG00000022528(C4orf29) ENSMUSG00000037818(3110057O12Rik) ENSG00000164074(C4orf29) "viable,fertile" FBgn0036586 CG13070 http://flybase.net/reports/FBgn0036586.html protein_coding_gene CG13070 16-Dec-15 2015_12 viable FBgn0010595 l(2)05327b lethal (2) 05327b http://flybase.net/reports/FBgn0010595.html gene l(2)05327 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0040052 CG17398 http://flybase.net/reports/FBgn0040052.html protein_coding_gene 16-Dec-15 2015_12 FBgn0037849 CG4596 http://flybase.net/reports/FBgn0037849.html protein_coding_gene IPR029386=TMEM169 protein CG4596 16-Dec-15 2015_12 viable FBgn0030309 CG1572 http://flybase.net/reports/FBgn0030309.html protein_coding_gene 0035208=positive regulation of hemocyte proliferation 0016020=membrane IPR008253=Marvel domain CG1572 16-Dec-15 2015_12 viable FBgn0000765 fs(1)A1001 female sterile (1) A1001 http://flybase.net/reports/FBgn0000765.html gene fs(1)1001 16-Dec-15 2015_12 "female sterile soma-dependent,recessive" FBgn0067658 sd-1 sd-1 http://flybase.net/reports/FBgn0067658.html gene "0007270=neuron-neuron synaptic transmission, 0042331=phototaxis" complementation group 1 16-Dec-15 2015_12 "viable,neurophysiology defective,somatic clone,phototaxis defective,lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0035192 CG9194 http://flybase.net/reports/FBgn0035192.html "FBgn0043930, FBgn0043931, FBgn0043932, FBgn0043934, FBgn0043935, FBgn0043936, FBgn0043937, FBgn0043938, FBgn0043939, FBgn0043940, FBgn0043941, FBgn0043942, FBgn0043943, FBgn0043944, FBgn0043945, FBgn0043946, FBgn0043947, FBgn0043948, FBgn0043949" protein_coding_gene "0005252=open rectifier potassium channel activity, 0005267=potassium channel activity" "0071805=potassium ion transmembrane transport, 0046331=lateral inhibition" 0016021=integral component of membrane "anon-WO0109301.23, anon-WO0109301.27, anon-WO0109301.20, anon-WO0109301.26, anon-WO0109301.38, anon-WO0109301.22, anon-WO0109301.19, anon-WO0109301.21, anon-WO0109301.36, anon-WO0109301.33, anon-WO0109301.28, anon-WO0109301.37, anon-WO0109301.24, anon-WO0109301.32, C9194, anon-WO0109301.29, anon-WO0109301.34, anon-WO0109301.31, anon-WO0109301.25, anon-WO0109301.3" "IPR013099=Potassium channel domain, IPR003280=Two pore domain potassium channel" CG9194 16-Dec-15 2015_12 WBGene00010784(K11H3.7) ENSXETG00000004192(KCNK18) "ENSMUSG00000046410(Kcnk6),ENSMUSG00000033998(Kcnk1),ENSMUSG00000023387,ENSMUSG00000024957(Kcnk4)" "ENSG00000099337(KCNK6),ENSG00000135750(KCNK1),ENSG00000095981(KCNK16),ENSG00000173338(KCNK7)" "visible,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0051934 CG31934 http://flybase.net/reports/FBgn0051934.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031021 ND-18 NADH dehydrogenase (ubiquinone) 18 kDa subunit http://flybase.net/reports/FBgn0031021.html protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0022900=electron transport chain 0005747=mitochondrial respiratory chain complex I "CG12203, NADH:ubiquinone oxidoreductase 18 kDa subunit, NADH ubiquinone oxidoreductase 18 kDa, FBpp0074481, NADH-ubiquinone oxidoreductase 18 kDa subunit, IP11020p, NUYM" "IPR006885=NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial" CG12203 16-Dec-15 2015_12 ENSDARG00000052840(ndufs4) WBGene00003061(lpd-5) ENSXETG00000023384(NDUFS4) ENSMUSG00000021764(Ndufs4) ENSG00000164258(NDUFS4) "viable,visible" trichogen cell FBgn0033651 Ir48c Ionotropic receptor 48c http://flybase.net/reports/FBgn0033651.html protein_coding_gene 0015276=ligand-gated ion channel activity "0009306=protein secretion, 0009593=detection of chemical stimulus, 0007030=Golgi organization" "0005783=endoplasmic reticulum, 0016021=integral component of membrane" "Transport and Golgi organization 3, CG12444, IR48c, ionotropic receptor 48c, DmelIR48c, TANGO3, Tango3" CG12444 16-Dec-15 2015_12 viable DRSC06154 IE 0.159248029 1.596882124 2.137769543 -1.341743998 -0.095900073 0.971379028 FBgn0262818 CG43189 http://flybase.net/reports/FBgn0262818.html protein_coding_gene CG43189 16-Dec-15 2015_12 FBgn0259393 EP-730 http://flybase.net/reports/FBgn0259393.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0264845 Tep5 Thioester-containing protein 5 http://flybase.net/reports/FBgn0264845.html "FBgn0032808, FBgn0032807, FBgn0041179" protein_coding_gene 0004866=endopeptidase inhibitor activity 0005615=extracellular space "TepV, TEP, CG13079, CG13080, dTEPV, Thiolester containing protein V, TEP5mel" "IPR011626=Alpha-macroglobulin complement component, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048=Alpha-macroglobulin, receptor-binding, IPR001599=Alpha-2-macroglobulin" CG13079 16-Dec-15 2015_12 FBgn0035587 Gdap1 GDAP1 ortholog http://flybase.net/reports/FBgn0035587.html protein_coding_gene "0007005=mitochondrion organization, 0000266=mitochondrial fission" 0005739=mitochondrion "GDAP1, CG4623" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold" CG4623 16-Dec-15 2015_12 "ENSDARG00000058601(gdap1),ENSDARG00000028628(gdap1l1)" ENSXETG00000001772(GDAP1L1) "ENSMUSG00000025777(Gdap1),ENSMUSG00000017943(Gdap1l1)" "ENSG00000104381(GDAP1),ENSG00000124194(GDAP1L1)" viable FBgn0060842 l(3)S049405b lethal (3) S049405b http://flybase.net/reports/FBgn0060842.html gene 0494/05 16-Dec-15 2015_12 lethal FBgn0028248 l(3)94Ba lethal (3) 94Ba http://flybase.net/reports/FBgn0028248.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0086545 MRE13 mRNA-like ncRNA in embryogenesis 13 http://flybase.net/reports/FBgn0086545.html non_protein_coding_gene GM09828 16-Dec-15 2015_12 FBgn0011120 l(1)Q81 lethal (1) Q81 http://flybase.net/reports/FBgn0011120.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0267798 CR46123 http://flybase.net/reports/FBgn0267798.html non_protein_coding_gene CR46123 16-Dec-15 2015_12 FBgn0265148 CR44217 http://flybase.net/reports/FBgn0265148.html non_protein_coding_gene lincRNA.223 CR44217 16-Dec-15 2015_12 FBgn0267449 WDY WD40 Y http://flybase.net/reports/FBgn0267449.html "FBgn0058449, FBan0041020, FBgn0085556, FBan0040551, FBgn0085496, FBan0040245, FBgn0058245, FBgn0085498, FBan0040583" protein_coding_gene "CG40551, CG40245, CG40583, CG45799, CG40449, CG41020, WDY" "IPR019775=WD40 repeat, conserved site, IPR011992=EF-hand domain pair, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG45799 16-Dec-15 2015_12 FBgn0262266 mir-980 mir-980 stem loop http://flybase.net/reports/FBgn0262266.html miRNA_gene 0009408=response to heat "miR-980, 980, CR42973" CR42973 16-Dec-15 2015_12 "visible,lethal" "wing,wing vein,ectopic,wing vein L4,wing margin,wing blade,2nd posterior cell" FBgn0031615 CG11933 http://flybase.net/reports/FBgn0031615.html protein_coding_gene 0032504=multicellular organism reproduction CT35796 16-Dec-15 2015_12 FBgn0065587 l(2)SH0909 lethal (2) SH0909 http://flybase.net/reports/FBgn0065587.html gene l(2)SH2 0909 16-Dec-15 2015_12 "lethal,recessive" FBgn0266980 CR45431 http://flybase.net/reports/FBgn0266980.html non_protein_coding_gene CR45431 16-Dec-15 2015_12 FBgn0267047 CG45491 http://flybase.net/reports/FBgn0267047.html protein_coding_gene CG45491 16-Dec-15 2015_12 FBgn0040873 CG12696 http://flybase.net/reports/FBgn0040873.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011382 l(3)j5C7 lethal (3) j5C7 http://flybase.net/reports/FBgn0011382.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005458 l(1)v455 lethal (1) v455 http://flybase.net/reports/FBgn0005458.html gene l(1)455 16-Dec-15 2015_12 FBgn0041128 l(2)45Ah lethal (2) 45Ah http://flybase.net/reports/FBgn0041128.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0260480 CG32295 http://flybase.net/reports/FBgn0260480.html "FBgn0052295, FBgn0045360, FBgn0045813" protein_coding_gene "BEST:GH20547, NEST:bs09a12, CG16757" IPR027831=Domain of unknown function DUF4485 CG32295 16-Dec-15 2015_12 FBgn0036091 CG18628 http://flybase.net/reports/FBgn0036091.html FBgn0063262 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space BcDNA:GH08251 CG18628 16-Dec-15 2015_12 viable FBgn0060588 l(3)S093705b lethal (3) S093705b http://flybase.net/reports/FBgn0060588.html gene 0937/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0262117 IntS3 Integrator 3 http://flybase.net/reports/FBgn0262117.html "FBgn0039997, FBan0017665, FBgn0067370, FBgn0067367, FBgn0022283" protein_coding_gene 0016180=snRNA processing "0005794=Golgi apparatus, 0032039=integrator complex" "Int3, l(2Rh)IR23, l(2)NC28, lethal (2) IR23, l(2)IR23, NC28, IR23, lethal (2) NC28, lethal (2) NC19, l(2)NC19, NC19, CG17665" IPR019333=Integrator complex subunit 3 CG17665 16-Dec-15 2015_12 ENSDARG00000016811(ints3) WBGene00022360(Y92H12A.4) ENSXETG00000002594() ENSMUSG00000027933(Ints3) ENSG00000143624(INTS3) DRSC21215 I 1.991568184 0.648212648 0.772768913 -0.565764732 0.779632106 1.004574303 FBgn0053541 CG33541 http://flybase.net/reports/FBgn0053541.html FBgn0069432 protein_coding_gene HDC14318 16-Dec-15 2015_12 FBgn0045476 Gr64e Gustatory receptor 64e http://flybase.net/reports/FBgn0045476.html "FBgn0035487, FBgn0045481, FBgn0052258, FBgn0053157" protein_coding_gene "0033041=sweet taste receptor activity, 0008527=taste receptor activity" "0050912=detection of chemical stimulus involved in sensory perception of taste, 0050909=sensory perception of taste, 0050916=sensory perception of sweet taste" 0016021=integral component of membrane "gr64e, Dmel64e, Gr64, CG14988, DmGr64e, CG33157, GR64e, Gustatory receptor 64A2, CG32258, Gr64A2" IPR009318=Gustatory receptor CG32258 16-Dec-15 2015_12 WBGene00001804(gur-3) "feeding behavior defective,taste perception defective" FBgn0044060 GTD74-236 GTD74-236 http://flybase.net/reports/FBgn0044060.html gene 16-Dec-15 2015_12 viable FBgn0032602 ppk17 pickpocket 17 http://flybase.net/reports/FBgn0032602.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "ppk17, CG13278, pickpocket 17" "IPR001873=Na+ channel, amiloride-sensitive" CG13278 16-Dec-15 2015_12 viable FBgn0028572 qtc quick-to-court http://flybase.net/reports/FBgn0028572.html FBgn0031679 protein_coding_gene "0000042=protein targeting to Golgi, 0046331=lateral inhibition, 0008049=male courtship behavior, 0048047=mating behavior, sex discrimination, 0007619=courtship behavior" CG14039 IPR000237=GRIP CG14039 16-Dec-15 2015_12 " adult stage | male , adult stage , adult stage | female " " adult head

, antennal segment 3

, testis

, retina

, optic lobe

, antennal segment 2

, central nervous system &&of adult head

, subesophageal ganglion

, adult brain cortex

, antenna

, ejaculatory bulb

, maxillary palpus

, olfactory sensory organ

, female reproductive system | restricted

" "viable,fertile,courtship behavior defective,male,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0067349 l(3)95Ec lethal (3) 95Ec http://flybase.net/reports/FBgn0067349.html gene 16-Dec-15 2015_12 "lethal,recessive" "wing margin,somatic clone,macrochaeta,eye,wing vein,embryo" FBgn0266057 Su(var)212 http://flybase.net/reports/FBgn0266057.html gene 212 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0065157 l(3)SH048 lethal (3) SH048 http://flybase.net/reports/FBgn0065157.html gene l(2)SH3 048 16-Dec-15 2015_12 "lethal,recessive" FBgn0053230 CG33230 http://flybase.net/reports/FBgn0053230.html FBgn0069053 protein_coding_gene CG33230 16-Dec-15 2015_12 ENSDARG00000036592(setd4) "YHL039W(EFM1),YPL208W(RKM1)" WBGene00022371(set-29) ENSXETG00000014132(TEgg124l22.1) ENSMUSG00000022948(Setd4) ENSG00000185917(SETD4) "viable,visible" trichogen cell FBgn0029937 CG8300 http://flybase.net/reports/FBgn0029937.html protein_coding_gene IPR028260=FAM177 family CG8300 16-Dec-15 2015_12 "ENSG00000197520(FAM177B),ENSG00000151327(FAM177A1)" viable FBgn0024889 Kap-ë±1 karyopherin ë±1 http://flybase.net/reports/FBgn0024889.html FBgn0062126 protein_coding_gene 0008320=protein transmembrane transporter activity "0007283=spermatogenesis, 0006606=protein import into nucleus" "0005737=cytoplasm, 0005643=nuclear pore" "Kap alpha1, karyopherin-alpha1, Kap-alpha1, imp-alpha1, Imp-alpha1, karyopherin alpha1, Dalpha1, Importin alpha1, importin-alpha1, importin alpha1, anon-WO0118547.276, Karyopherin-alpha1, Kapalpha1S1, IMPalpha1, CG8548, Importin-alpha1, Dmalpha1, karyopherin alpha 1, impalpha1, alphaKap1, Kpna1, imp alpha1" "IPR011989=Armadillo-like helical, IPR024931=Importin subunit alpha, IPR002652=Importin-alpha, importin-beta-binding domain, IPR016024=Armadillo-type fold, IPR000225=Armadillo" CG8548 16-Dec-15 2015_12 "ENSDARG00000044980(LOC100149852),ENSDARG00000042030(kpna5),ENSDARG00000016360(LOC572542)" YNL189W(SRP1) "ENSXETG00000005242(kpna6),ENSXETG00000020837(kpna1)" "ENSMUSG00000003731(Kpna6),ENSMUSG00000022905(Kpna1)" "ENSG00000025800(KPNA6),ENSG00000196911(KPNA5),ENSG00000114030(KPNA1)" "male sterile,lethal,heat sensitive,viable" tergite FBgn0060790 l(3)SzB90Cm lethal (3) SzB90Cm http://flybase.net/reports/FBgn0060790.html gene "0592/13, l(3)S059213b" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0069341 TAHRE\pol pol http://flybase.net/reports/FBgn0069341.html transposable_element_gene ORF2 "IPR005135=Endonuclease/exonuclease/phosphatase, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0028231 l(3)S004021 lethal (3) S004021 http://flybase.net/reports/FBgn0028231.html gene 0040/21 16-Dec-15 2015_12 "lethal,recessive" FBgn0044075 E(rst)I19 E(rst)I19 http://flybase.net/reports/FBgn0044075.html gene 0001745=compound eye morphogenesis I19 16-Dec-15 2015_12 viable FBgn0027526 Ublcp1 Ubiquitin-like domain-containing C-terminal domain phosphatase 1 http://flybase.net/reports/FBgn0027526.html protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation 0005634=nucleus "CG6697, UBLCP1, DmUBLCP1, BcDNA:LD21504, 4972728" "IPR029071=Ubiquitin-related domain, IPR004274=FCP1 homology domain, IPR000626=Ubiquitin domain, IPR023214=HAD-like domain, IPR011943=HAD-superfamily hydrolase, subfamily IIID" CG6697 16-Dec-15 2015_12 "ENSDARG00000044492(wu:fb33g09),ENSDARG00000054520" ENSXETG00000016360(TGas135j05.1) ENSMUSG00000041231(Ublcp1) ENSG00000164332(UBLCP1) viable FBgn0037435 CG18048 http://flybase.net/reports/FBgn0037435.html protein_coding_gene 0008168=methyltransferase activity 0008033=tRNA processing "IPR022776=TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain, IPR007871=Methyltransferase TRM13, IPR021721=Zinc finger, CCCH-type, TRM13" CG18048 16-Dec-15 2015_12 ENSDARG00000042701(ccdc76) YOL125W(TRM13) WBGene00013026(Y49A3A.3) ENSXETG00000013204(CCDC76) ENSMUSG00000033439(Ccdc76) ENSG00000122435(CCDC76) viable FBgn0027265 l(1)G0220 lethal (1) G0220 http://flybase.net/reports/FBgn0027265.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,male,female" FBgn0265096 CR44201 http://flybase.net/reports/FBgn0265096.html non_protein_coding_gene CR44201 16-Dec-15 2015_12 FBgn0267544 CR45884 http://flybase.net/reports/FBgn0267544.html non_protein_coding_gene CR45884 16-Dec-15 2015_12 FBgn0260370 GSd309 http://flybase.net/reports/FBgn0260370.html gene 16-Dec-15 2015_12 lethal FBgn0065702 l(2)SH0620 lethal (2) SH0620 http://flybase.net/reports/FBgn0065702.html gene l(2)SH2 0620 16-Dec-15 2015_12 "lethal,recessive" FBgn0011409 l(3)j8B6 lethal (3) j8B6 http://flybase.net/reports/FBgn0011409.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044441 HMS-Beagle\pol pol http://flybase.net/reports/FBgn0044441.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "midline-jumper\pol, midline-element\pol" "IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR021109=Aspartic peptidase domain" 16-Dec-15 2015_12 FBgn0011029 l(3)s2521 lethal (3) s2521 http://flybase.net/reports/FBgn0011029.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0084047 CG41516 http://flybase.net/reports/FBgn0084047.html FBan0000000 protein_coding_gene 16-Dec-15 2015_12 FBgn0052311 zormin zormin http://flybase.net/reports/FBgn0052311.html "FBan0032310, FBan0032307, FBgn0035303, FBgn0035304, FBgn0035305, FBgn0035306, FBgn0035307, FBgn0052307, FBgn0052309, FBgn0052310, FBgn0053484, FBgn0062502" protein_coding_gene "0003779=actin binding, 0005515=protein binding" "0031430=M band, 0030018=Z disc" "CT36990, BcDNA:GH09541, CG33484, CG32311, CG11953, D-Titin, CG32309, CG5699, D-titin, CG11850, Zormin, CG1282, CG32307, CG11952, CG32310, titin" "IPR002017=Spectrin repeat, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR018159=Spectrin/alpha-actinin" CG33484 16-Dec-15 2015_12 "ENSDARG00000003684(LOC796577),ENSDARG00000069235" WBGene00004130(ketn-1) ENSXETG00000015049() "viable,visible,planar polarity defective" "trichogen cell,mesothoracic tergum,chaeta,supernumerary" FBgn0051787 CG31787 http://flybase.net/reports/FBgn0051787.html protein_coding_gene "0005102=receptor binding, 0005215=transporter activity" "0006810=transport, 0048193=Golgi vesicle transport" 0016021=integral component of membrane p24 "IPR009038=GOLD domain, IPR015720=TMP21-related" CG31787 16-Dec-15 2015_12 "YAL007C(ERP2),YOR016C(ERP4)" WBGene00010670(K08E4.6) viable DRSC01632 E -0.22589936 0.024686309 -1.510855192 -1.054397393 -0.307105363 0.295794255 FBgn0005505 l(2)24EFc lethal (2) 24EFc http://flybase.net/reports/FBgn0005505.html gene l(2)Gr.III 16-Dec-15 2015_12 "lethal,recessive" FBgn0029814 CG15765 http://flybase.net/reports/FBgn0029814.html protein_coding_gene 0030246=carbohydrate binding 0007399=nervous system development "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG15765 16-Dec-15 2015_12 "viable,fertile" FBgn0031497 CG17259 http://flybase.net/reports/FBgn0031497.html protein_coding_gene "0005524=ATP binding, 0004828=serine-tRNA ligase activity" 0006434=seryl-tRNA aminoacylation 0005737=cytoplasm "SerRS, seryl-tRNA synthetase, DmSRS1" "IPR006195=Aminoacyl-tRNA synthetase, class II, IPR015866=Serine-tRNA synthetase, type1, N-terminal, IPR002317=Serine-tRNA ligase, type1, IPR010978=tRNA-binding arm, IPR002314=Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)" CG17259 16-Dec-15 2015_12 ENSDARG00000008237(sars) YDR023W(SES1) WBGene00005663(sars-1) ENSXETG00000008009(sars) ENSMUSG00000068739(Sars) ENSG00000031698(SARS) lysosome & larval fat body | somatic clone | cell autonomous FBgn0002404 l(3)99De lethal (3) 99De http://flybase.net/reports/FBgn0002404.html gene 16-Dec-15 2015_12 lethal FBgn0011778 l(2)DTS91 lethal (2) DTS91 http://flybase.net/reports/FBgn0011778.html gene "DTS-91, DTS91, unnamed" 16-Dec-15 2015_12 "lethal,dominant,heat sensitive" FBgn0020551 fs(2)35Ec fs(2)35Ec http://flybase.net/reports/FBgn0020551.html gene 16-Dec-15 2015_12 FBgn0050378 CG30378 http://flybase.net/reports/FBgn0050378.html FBgn0045369 protein_coding_gene 0005509=calcium ion binding NEST:bs08d04 "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG30378 16-Dec-15 2015_12 viable FBgn0266036 CR44801 http://flybase.net/reports/FBgn0266036.html non_protein_coding_gene lincRNA.6 CR44801 16-Dec-15 2015_12 FBgn0034805 CG13534 http://flybase.net/reports/FBgn0034805.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260354 GSd201 http://flybase.net/reports/FBgn0260354.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0001674 l(1)EN11 lethal (1) from Eugene Nonautonomous 11 http://flybase.net/reports/FBgn0001674.html gene 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" melanotic mass FBgn0000976 fs(2)HO103 female sterile (2) HO103 http://flybase.net/reports/FBgn0000976.html gene fs(2)103B 16-Dec-15 2015_12 FBgn0083241 EP2 EP2 http://flybase.net/reports/FBgn0083241.html gene 16-Dec-15 2015_12 FBgn0264572 CR43944 http://flybase.net/reports/FBgn0264572.html non_protein_coding_gene CR43944 16-Dec-15 2015_12 FBgn0002275 l(3)70Ac lethal (3) 70Ac http://flybase.net/reports/FBgn0002275.html gene l(3)ZF3 16-Dec-15 2015_12 lethal FBgn0033713 CG8841 http://flybase.net/reports/FBgn0033713.html protein_coding_gene Dmc1 IPR026705=Hid-1 CG8841 16-Dec-15 2015_12 ENSDARG00000015091(zgc:100980) WBGene00001844(hid-1) ENSXETG00000027066(BC064723.1) ENSMUSG00000034586(C630004H02Rik) ENSG00000167861(C17orf28) viable FBgn0037544 CG11035 http://flybase.net/reports/FBgn0037544.html FBgn0062016 protein_coding_gene 0051087=chaperone binding 0009408=response to heat anon-WO0118547.426 "IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site" CG11035 16-Dec-15 2015_12 WBGene00001036(dnj-18) ENSMUSG00000061118(Dnajc30) ENSG00000176410(DNAJC30) viable FBgn0060708 l(3)S070316 lethal (3) S070316 http://flybase.net/reports/FBgn0060708.html gene 0703/16 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065528 l(2)SH1114 lethal (2) SH1114 http://flybase.net/reports/FBgn0065528.html gene l(2)SH2 1114 16-Dec-15 2015_12 "lethal,recessive" FBgn0029020 l(3)77CDd lethal (3) 77CDd http://flybase.net/reports/FBgn0029020.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0085613 CG41322 http://flybase.net/reports/FBgn0085613.html FBan0041322 protein_coding_gene 16-Dec-15 2015_12 FBgn0051821 CG31821 http://flybase.net/reports/FBgn0051821.html FBgn0028933 protein_coding_gene 0004185=serine-type carboxypeptidase activity 0006508=proteolysis "CG7647, BG:DS00365.3" "IPR001563=Peptidase S10, serine carboxypeptidase, IPR018202=Peptidase S10, serine carboxypeptidase, active site, IPR029058=Alpha/Beta hydrolase fold" CG31821 16-Dec-15 2015_12 ENSDARG00000040072(scpep1) YGL203C(KEX1) WBGene00012530(Y32F6A.5) ENSXETG00000020061(SCPEP1) ENSMUSG00000000278(Scpep1) ENSG00000121064(SCPEP1) "viable,visible" trichogen cell FBgn0262470 EP1318 http://flybase.net/reports/FBgn0262470.html gene 16-Dec-15 2015_12 FBgn0014049 Su(tor)2-278 Su(tor)2-278 http://flybase.net/reports/FBgn0014049.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0065201 l(2)SH2293 lethal (2) SH2293 http://flybase.net/reports/FBgn0065201.html gene l(2)SH2 2293 16-Dec-15 2015_12 "lethal,recessive" FBgn0013684 mt:ND5 mitochondrial NADH-ubiquinone oxidoreductase chain 5 http://flybase.net/reports/FBgn0013684.html FBgn0002867 protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0042773=ATP synthesis coupled electron transport "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "URF5, NADH-ubiquinone oxidoreductase subunit 5, NADH-ubiquinone oxidoreductase chain subunit 5, nad5, ND5, nd5, ND5 subunit of mitochondrial complex I, NADH5, CG34083" "IPR010934=NADH dehydrogenase subunit 5, C-terminal, IPR018393=NADH-plastoquinone oxidoreductase, chain 5 subgroup, IPR001516=NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal, IPR001750=NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit" CG34083 16-Dec-15 2015_12 ENSDARG00000063921 WBGene00010967(MTCE.35) ENSMUSG00000064367 ENSG00000198786 FBgn0052831 CG33695 http://flybase.net/reports/FBgn0052831.html "FBgn0022074, FBgn0032356, FBgn0032357, FBgn0052955, FBgn0053695, FBtr0080206, FBpp0079795, FBtr0080207, FBtr0080208, FBtr0080209, FBtr0080210, FBtr0080211" protein_coding_gene 0003677=DNA binding "CG32831, CG4831, CG32955, CG32955-ORFB, CG16917, l(2)k07716" "IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like" CG33695 16-Dec-15 2015_12 DRSC01163 IE -1.874611492 -1.177843601 2.49473981 0.328624915 0.114850001 -0.329066544 FBgn0050462 ste24c ste24c prenyl protease type I http://flybase.net/reports/FBgn0050462.html "FBgn0063335, FBgn0034174, FBgn0053142, FBtr0087061, FBpp0086209, FBtr0087062, FBpp0086210, FBtr0087063, FBpp0086211, FBtr0087064, FBpp0086212, FBtr0087065, FBpp0086213, FBtr0087066, FBpp0086214" protein_coding_gene 0004222=metalloendopeptidase activity "0071586=CAAX-box protein processing, 0007283=spermatogenesis" 0016020=membrane "CG9002, Dmel\Ste24, prenyl protease type I, ste24c, Dmel\Ste24c, CG33142, CG30462" "IPR027057=CAAX prenyl protease 1, IPR001915=Peptidase M48" CG9002 16-Dec-15 2015_12 "viable,fertile" FBgn0030478 CG1640 http://flybase.net/reports/FBgn0030478.html protein_coding_gene "0004021=L-alanine:2-oxoglutarate aminotransferase activity, 0030170=pyridoxal phosphate binding" 0009058=biosynthetic process "0005829=cytosol, 0005739=mitochondrion" "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015424=Pyridoxal phosphate-dependent transferase, IPR004839=Aminotransferase, class I/classII" CG1640 16-Dec-15 2015_12 "ENSDARG00000012199(gpt2),ENSDARG00000019541(gpt2l),ENSDARG00000055642(LOC100148522)" "YLR089C(ALT1),YDR111C(ALT2)" WBGene00016333(C32F10.8) "ENSXETG00000003895(GPT2),ENSXETG00000007140(gpt2)" "ENSMUSG00000031700(Gpt2),ENSMUSG00000022546(Gpt)" "ENSG00000166123(GPT2),ENSG00000167701(GPT)" "viable,fertile,visible" trichogen cell FBgn0083288 E(smoDN)2070 Enhancer of smoDN 2070 http://flybase.net/reports/FBgn0083288.html gene 16-Dec-15 2015_12 FBgn0026646 l(2)k02405 lethal (2) k02405 http://flybase.net/reports/FBgn0026646.html gene 16-Dec-15 2015_12 FBgn0010881 l(3)05967 lethal (3) 05967 http://flybase.net/reports/FBgn0010881.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002212 l(3)67BDj lethal (3) 67BDj http://flybase.net/reports/FBgn0002212.html gene l(3)e80A6-2 16-Dec-15 2015_12 lethal FBgn0044416 Scim11 Sensitized chromosome inheritance modifier 11 http://flybase.net/reports/FBgn0044416.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0265757 CR44564 http://flybase.net/reports/FBgn0265757.html non_protein_coding_gene lincRNA.589 CR44564 16-Dec-15 2015_12 FBgn0069218 gl(3R)60-38 gl(3R)60-38 http://flybase.net/reports/FBgn0069218.html gene 0009952=anterior/posterior pattern specification 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryo,germline clone,maternal effect,posterior" FBgn0033081 geminin geminin http://flybase.net/reports/FBgn0033081.html "FBgn0021864, FBgn0028557, FBgn0063803" protein_coding_gene 0003677=DNA binding "0007113=endomitotic cell cycle, 0008156=negative regulation of DNA replication, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0007348=regulation of syncytial blastoderm mitotic cell cycle, 0051726=regulation of cell cycle, 0007307=eggshell chorion gene amplification" 0005634=nucleus "Geminin, Gem, v(2)k09107, gem, anon-WO0257455.1, CG3183, Dm Geminin, Dm geminin, l(2)k14019" IPR022786=Geminin/Multicilin CG3183 16-Dec-15 2015_12 ENSDARG00000035957(gmnn) "ENSMUSG00000006715(Gmnn),ENSMUSG00000074651(Gm6320)" ENSG00000112312(GMNN) "lethal - all die before end of P-stage,some die during P-stage,lethal,recessive,visible,female sterile,partially,increased cell death,endomitotic cell cycle defective,mitotic cell cycle defective" "imaginal disc,follicle cell,cycle 16 embryo,mitotic cell cycleST1),mitotic anaphaseST1),anaphase & condensed nuclear chromosomeST1),embryonic/larval midgut primordium,embryonic hindgut,embryonic Malpighian tubule,presumptive embryonic/larval central nervous system,eye disc,eye,S phaseGMR.PF,ommatidium,S phaseen-e16E,mitotic M phaseen-e16E,embryonic/larval neuron,ectopic,presumptive embryonic/larval peripheral nervous system,peripheral nervous system,S phaseey.PH,lch5 neuron,wing disc | third instar larval stage" DRSC04984 K -0.284681822 -0.79704177 -0.04788526 -0.75284165 2.502252921 3.215856551 FBgn0041751 hocher hocher http://flybase.net/reports/FBgn0041751.html gene 16-Dec-15 2015_12 visible adult thorax FBgn0060750 l(3)S065104b lethal (3) S065104b http://flybase.net/reports/FBgn0060750.html gene 0651/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266952 CR45403 http://flybase.net/reports/FBgn0266952.html non_protein_coding_gene CR45403 16-Dec-15 2015_12 FBgn0010840 l(3)04449 lethal (3) 04449 http://flybase.net/reports/FBgn0010840.html gene "1295/10, 0708/15, 86/14, 0086/14" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025868 C8-3-37 C8-3-37 http://flybase.net/reports/FBgn0025868.html gene 16-Dec-15 2015_12 "viable,fertile" FBgn0262608 CG43134 http://flybase.net/reports/FBgn0262608.html protein_coding_gene CG43134 16-Dec-15 2015_12 FBgn0267916 CR46197 http://flybase.net/reports/FBgn0267916.html non_protein_coding_gene lincRNA.579 CR46197 16-Dec-15 2015_12 FBgn0035539 slow slowdown http://flybase.net/reports/FBgn0035539.html protein_coding_gene 0005509=calcium ion binding "0044719=regulation of imaginal disc-derived wing size, 0016203=muscle attachment, 0008039=synaptic target recognition" 0005927=muscle tendon junction "blade runner, N-like, Slow, Slowdowm, slomo, CT22877, CG7447, blr, slowmotion" "IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR011489=EMI domain, IPR001881=EGF-like calcium-binding domain, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG7447 16-Dec-15 2015_12 "ENSDARG00000069265(matn3b),ENSDARG00000069245(matn3a)" "partially lethal - majority live,locomotor rhythm defective,flight defective,size defective,viable" "embryonic/larval somatic muscle,muscle attachment site,wing,posterior" FBgn0035004 Pgam5-2 Phosphoglycerate mutase 5-2 http://flybase.net/reports/FBgn0035004.html protein_coding_gene 0004721=phosphoprotein phosphatase activity "0090141=positive regulation of mitochondrial fission, 0006470=protein dephosphorylation" "CG15874, dPGAM5-2" "IPR029033=Histidine phosphatase superfamily, IPR013078=Histidine phosphatase superfamily, clade-1" CG15874 16-Dec-15 2015_12 ENSG00000176894(PXMP2) "short lived,viable,fertile" mitochondrionda.G32 FBgn0034662 CG13492 http://flybase.net/reports/FBgn0034662.html protein_coding_gene IPR008472=Domain of unknown function DUF753 CG13492 16-Dec-15 2015_12 viable FBgn0000168 bd balding http://flybase.net/reports/FBgn0000168.html gene bald 16-Dec-15 2015_12 "visible,recessive" acrostichal bristle FBgn0085707 CG41581 http://flybase.net/reports/FBgn0085707.html FBan0041581 protein_coding_gene 16-Dec-15 2015_12 FBgn0035590 Prpk p53-related protein kinase ortholog http://flybase.net/reports/FBgn0035590.html protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0030307=positive regulation of cell growth, 0040018=positive regulation of multicellular organism growth, 0006468=protein phosphorylation, 0032008=positive regulation of TOR signaling" "0016020=membrane, 0005737=cytoplasm" CG10673 "IPR011009=Protein kinase-like domain, IPR010440=Lipopolysaccharide kinase, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain, IPR022495=Serine/threonine-protein kinase Bud32" CG10673 16-Dec-15 2015_12 ENSDARG00000059375 YGR262C(BUD32) WBGene00138717(F52C12.6) ENSXETG00000003469(TP53RK) "ENSMUSG00000042854(Trp53rk),ENSMUSG00000039725(2810408M09Rik)" ENSG00000172315(TP53RK) "visible,decreased cell size,small body,lethal,viable" "1st posterior cell,wing disc,somatic clone | third instar larval stage,embryonic/larval fat body" FBgn0069139 mcl(3)Z5578 mcl(3)Z5578 http://flybase.net/reports/FBgn0069139.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0024630 l(2)k14403 lethal (2) k14403 http://flybase.net/reports/FBgn0024630.html gene 144/3 16-Dec-15 2015_12 "lethal,recessive" FBgn0262180 mir-2283 mir-2283 stem loop http://flybase.net/reports/FBgn0262180.html miRNA_gene "miR-2283, dme-mir-2283, CR42887" CR42887 16-Dec-15 2015_12 viable FBgn0013734 spb split brain http://flybase.net/reports/FBgn0013734.html gene 0007420=brain development 16-Dec-15 2015_12 FBgn0065408 l(2)SH1576 lethal (2) SH1576 http://flybase.net/reports/FBgn0065408.html gene l(2)SH2 1576 16-Dec-15 2015_12 "lethal,recessive" FBgn0019890 Smg5 Smg5 http://flybase.net/reports/FBgn0019890.html FBgn0027901 protein_coding_gene "0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0035195=gene silencing by miRNA, 0016246=RNA interference" "SMG5, unnamed, anon-34Ea, CG8954, smg5, BG:DS08220.2, dSMG5" "IPR018834=DNA/RNA-binding domain, Est1-type, IPR002716=PIN domain, IPR019458=Telomerase activating protein Est1" CG8954 16-Dec-15 2015_12 ENSDARG00000041481(smg5) ENSMUSG00000001415(Smg5) ENSG00000198952(SMG5) "viable,neuroanatomy defective" "intersegmental nerve,anterior fascicle & synapse" DRSC03124 IE -0.924971499 -4.650349812 -1.236786519 -2.743007985 0.111009153 -0.350325352 FBgn0011157 l(1)Q235 lethal (1) Q235 http://flybase.net/reports/FBgn0011157.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0004773 l(3)91Cb lethal (3) 91Cb http://flybase.net/reports/FBgn0004773.html gene l(3)CR2 16-Dec-15 2015_12 lethal FBgn0084237 2335 2335 http://flybase.net/reports/FBgn0084237.html gene 16-Dec-15 2015_12 FBgn0026219 l(3)05143 lethal (3) 05143 http://flybase.net/reports/FBgn0026219.html gene 16-Dec-15 2015_12 lethal FBgn0024624 l(3)63Dc lethal (3) 63Dc http://flybase.net/reports/FBgn0024624.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0037846 CG6574 http://flybase.net/reports/FBgn0037846.html protein_coding_gene 0008518=reduced folate carrier activity 0006810=transport 0016020=membrane "IPR002666=Reduced folate carrier, IPR020846=Major facilitator superfamily domain" CG6574 16-Dec-15 2015_12 "ENSDARG00000059712(LOC100329244),ENSDARG00000061103(slc19a3),ENSDARG00000006447(LOC557854)" "WBGene00018138(folt-2),WBGene00044738(folt-3)" "ENSXETG00000002422(SLC19A2),ENSXETG00000008390(TGas049p21.1),ENSXETG00000014773(BC075531.1),ENSXETG00000011482(SLC19A1)" "ENSMUSG00000038496(Slc19a3),ENSMUSG00000040918(Slc19a2)" "ENSG00000117479(SLC19A2),ENSG00000135917(SLC19A3),ENSG00000173638(SLC19A1)" "viable,fertile" DRSC16070 K -0.791634782 0.145794394 -0.082180911 0.179523725 -0.366187422 1.596677914 FBgn0267442 CR45792 http://flybase.net/reports/FBgn0267442.html non_protein_coding_gene Mgn94021 CR45792 16-Dec-15 2015_12 FBgn0005375 x5 x5 http://flybase.net/reports/FBgn0005375.html gene 16-Dec-15 2015_12 FBgn0005319 neu neuter http://flybase.net/reports/FBgn0005319.html gene "neuralized, Neu" 16-Dec-15 2015_12 "sex-determination defective,female,recessive,male fertile" FBgn0065664 l(2)SH0702 lethal (2) SH0702 http://flybase.net/reports/FBgn0065664.html gene l(2)SH2 0702 16-Dec-15 2015_12 "lethal,recessive" FBgn0024249 cato cousin of atonal http://flybase.net/reports/FBgn0024249.html protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0007423=sensory organ development" 0005634=nucleus "bHLHa12, CG7760, Cato, DATH-B, Drosophila atonal homologue" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG7760 16-Dec-15 2015_12 WBGene00001959(hlh-15) ENSMUSG00000052271(Bhlha15) " larval stage , embryonic stage | stage 11-13 , embryonic stage | stage 10-13 , embryonic stage | stage 10,11 , embryonic stage | stage 10 " " peripheral nervous system

, sensory mother cell

, embryonic peripheral nervous system

, chordotonal organ precursor cell

, external sensory organ precursor cell

, imaginal disc

, C1 chordotonal organ precursor cell

" "viable,neuroanatomy defective" "chordotonal organ,ectopic,macrochaeta,scolopidium,scolopidial neuron,supernumerary,abdominal lch1 neuron" FBgn0266727 CR45200 http://flybase.net/reports/FBgn0266727.html non_protein_coding_gene CR45200 16-Dec-15 2015_12 FBgn0062700 EP1113 EP1113 http://flybase.net/reports/FBgn0062700.html gene EP(3)1113 16-Dec-15 2015_12 FBgn0031805 CG9505 http://flybase.net/reports/FBgn0031805.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain, IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13" CG9505 16-Dec-15 2015_12 viable FBgn0001086 fzy fizzy http://flybase.net/reports/FBgn0001086.html protein_coding_gene 0090302=APC-Cdc20 complex activity "0006909=phagocytosis, 0097150=neuronal stem cell maintenance, 0051488=activation of anaphase-promoting complex activity, 0007144=female meiosis I, 0007147=female meiosis II, 0000278=mitotic cell cycle, 0060547=negative regulation of necrotic cell death, 0022008=neurogenesis, 0007096=regulation of exit from mitosis, 0030718=germ-line stem cell maintenance, 0030163=protein catabolic process, 0007067=mitotic nuclear division, 0030162=regulation of proteolysis, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation" "0005819=spindle, 0005680=anaphase-promoting complex, 0005813=centrosome, 0000776=kinetochore, 0005737=cytoplasm" "CG4274, FZY, cdc20, CDC20, cdc20/fizzy, dCDC20, Cdc20[Fzy], Cdc20, Cdc20/Fizzy, BG:DS02740.14, Cdc20/Fzy, Fzy, Cdc20[fizzy], Fizzy, dFZY, Fzy/Cdc20" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site" CG4274 16-Dec-15 2015_12 ENSDARG00000020192(cdc20) ENSXETG00000025623(cdc20) ENSMUSG00000006398(Cdc20) ENSG00000117399(CDC20) " embryonic stage | stage 14 , embryonic stage | stage 11 , embryonic stage | stage 5-10 " " neuroblast | restricted

, embryonic central nervous system | presumptive

,

ubiquitous , ganglion mother cell | restricted

" "neuroanatomy defective,locomotor behavior defective,somatic clone,progressive,visible,wild-type,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive,meiotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" "neuroblast,neuropil,somatic clone,wing,mitotic cell cycle & epidermis & embryo | ventral,mitotic cell cycle & spindle & epidermis & embryo | ventral,female germline stem cell,germline clone,embryonic ventral nervous system,embryonic ventral epidermis,spindle | embryonic stage,mitotic cell cycle,mitosis & nuclear chromosome,embryonic/larval optic lobe,posterior compartment,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" DRSC03534 IE -0.762369643 -3.972417903 -1.465568427 -4.982800005 -0.506211735 1.238405932 FBgn0058175 CG40175 http://flybase.net/reports/FBgn0058175.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262894 CG43249 http://flybase.net/reports/FBgn0262894.html protein_coding_gene lincRNA.583 CG43249 16-Dec-15 2015_12 FBgn0019754 l(1)7B lethal (1) 7B http://flybase.net/reports/FBgn0019754.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002156 l(2)MV lethal (2) MV http://flybase.net/reports/FBgn0002156.html gene lethal (2) of Mglinetz and Vikulova 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,fertile" FBgn0025918 mei-99 mei-99 http://flybase.net/reports/FBgn0025918.html gene "0007131=reciprocal meiotic recombination, 0016321=female meiosis chromosome segregation" 16-Dec-15 2015_12 FBgn0004395 unk unkempt http://flybase.net/reports/FBgn0004395.html protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" "0008407=chaeta morphogenesis, 0048749=compound eye development, 0030182=neuron differentiation, 0050767=regulation of neurogenesis, 0002164=larval development, 0007476=imaginal disc-derived wing morphogenesis" 0005737=cytoplasm "CG4620, Unkempt" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000571=Zinc finger, CCCH-type, IPR001841=Zinc finger, RING-type" CG4620 16-Dec-15 2015_12 "ENSDARG00000000935(unk),ENSDARG00000037838(LOC565405)" WBGene00016407(C34D10.2) "ENSMUSG00000015127(Unkl),ENSMUSG00000020770(Unk)" ENSG00000132478(UNK) " embryonic stage | stage 1-15 , embryonic stage , embryonic stage | stage 13-17 " "

ubiquitous , embryonic central nervous system

" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,visible,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,ommatidium,wing,scutellar bristle,trichogen cell" DRSC17093 E -0.489287832 -0.188488417 0.269309836 -1.519441135 -0.0451476 0.17268388 FBgn0014417 CG13397 http://flybase.net/reports/FBgn0014417.html FBgn0032041 protein_coding_gene 0004561=alpha-N-acetylglucosaminidase activity "anon-sts19, 172F5T, ESTS:172F5T" "IPR024732=Alpha-N-acetylglucosaminidase, C-terminal, IPR024240=Alpha-N-acetylglucosaminidase, N-terminal, IPR017853=Glycoside hydrolase superfamily, IPR024733=Alpha-N-acetylglucosaminidase, tim-barrel domain, IPR007781=Alpha-N-acetylglucosaminidase" CG13397 16-Dec-15 2015_12 ENSDARG00000030156(LOC560126) WBGene00010722(K09E4.4) ENSMUSG00000001751(Naglu) ENSG00000108784(NAGLU) "viable,fertile" FBgn0014889 Su(phl)9 Suppressor of pole hole 9 http://flybase.net/reports/FBgn0014889.html gene "Su(D-raf)9, Suppressor of raf-like-oncogene" 16-Dec-15 2015_12 FBgn0260487 CG42534 http://flybase.net/reports/FBgn0260487.html "FBgn0039514, FBgn0039512, FBgn0039513" protein_coding_gene "CG6599, CG14264, CG13980" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG42534 16-Dec-15 2015_12 ENSXETG00000023058(INVS) FBgn0265928 CR44717 http://flybase.net/reports/FBgn0265928.html non_protein_coding_gene lincRNA.504 CR44717 16-Dec-15 2015_12 FBgn0000292 Cg16-17 Collagen-like 16-17 http://flybase.net/reports/FBgn0000292.html gene "DCg6, Cg6" 16-Dec-15 2015_12 FBgn0001868 l(1)XC46 lethal (1) XC46 http://flybase.net/reports/FBgn0001868.html gene 16-Dec-15 2015_12 FBgn0037603 CG11753 http://flybase.net/reports/FBgn0037603.html protein_coding_gene 0000139=Golgi membrane "IPR016973=Integral membrane protein SYS1, IPR019185=Integral membrane protein SYS1-related" CG11753 16-Dec-15 2015_12 ENSDARG00000017606(zgc:56445) YJL004C(SYS1) WBGene00020193(T03F1.12) ENSXETG00000025807(TGas033k17.1) ENSMUSG00000045503(Sys1) ENSG00000198641 "body color defective,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0264985 CR44136 http://flybase.net/reports/FBgn0264985.html non_protein_coding_gene CR44136 16-Dec-15 2015_12 FBgn0065945 l(2)SH0107 lethal (2) SH0107 http://flybase.net/reports/FBgn0065945.html gene l(2)SH2 0107 16-Dec-15 2015_12 "lethal,recessive" FBgn0065839 l(2)SH0328 lethal (2) SH0328 http://flybase.net/reports/FBgn0065839.html gene l(2)SH2 0328 16-Dec-15 2015_12 "lethal,recessive" FBgn0039249 CG11168 http://flybase.net/reports/FBgn0039249.html protein_coding_gene "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG11168 16-Dec-15 2015_12 WBGene00007520(C11E4.6) ENSXETG00000015109(ANKS1A) ENSMUSG00000024219(Anks1) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0034658 Grx-1 Grx-1 http://flybase.net/reports/FBgn0034658.html protein_coding_gene "0015036=disulfide oxidoreductase activity, 0015035=protein disulfide oxidoreductase activity, 0009055=electron carrier activity" 0045454=cell redox homeostasis CG7975 "IPR011899=Glutaredoxin, eukaryotic/virial, IPR002109=Glutaredoxin, IPR012336=Thioredoxin-like fold, IPR014025=Glutaredoxin subgroup" CG7975 16-Dec-15 2015_12 ENSDARG00000042631(glrx2) "YDR513W(GRX2),YCL035C(GRX1)" WBGene00021331(glrx-10) ENSXETG00000004534(glrx2) ENSMUSG00000018196(Glrx2) ENSG00000023572(GLRX2) viable FBgn0000015 Abd-B Abdominal B http://flybase.net/reports/FBgn0000015.html "FBgn0002692, FBgn0010098, FBgn0026843, FBgn0026859, FBgn0038456, FBgn0038457" protein_coding_gene "0000976=transcription regulatory region sequence-specific DNA binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007621=negative regulation of female receptivity, 0045705=negative regulation of salivary gland boundary specification, 0048066=developmental pigmentation, 0035261=external genitalia morphogenesis, 0048087=positive regulation of developmental pigmentation, 0007424=open tracheal system development, 1902339=positive regulation of apoptotic process involved in morphogenesis, 0007385=specification of segmental identity, abdomen, 0007507=heart development, 0045843=negative regulation of striated muscle tissue development, 0048094=male pigmentation, 0007280=pole cell migration, 0009997=negative regulation of cardioblast cell fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007548=sex differentiation, 0035277=spiracle morphogenesis, open tracheal system, 0007506=gonadal mesoderm development, 0007379=segment specification, 0035224=genital disc anterior/posterior pattern formation, 0007486=imaginal disc-derived female genitalia development, 0008406=gonad development, 0048071=sex-specific pigmentation, 0008595=anterior/posterior axis specification, embryo, 0030539=male genitalia development, 0035215=genital disc development, 0061101=neuroendocrine cell differentiation, 0035225=determination of genital disc primordium, 0008584=male gonad development, 0008354=germ cell migration, 0060439=trachea morphogenesis, 0030540=female genitalia development, 0007431=salivary gland development, 0007494=midgut development, 0007484=imaginal disc-derived genitalia development, 0035263=genital disc sexually dimorphic development, 0046693=sperm storage" 0005634=nucleus "abd-B, AbdominalB, AbdB, Abdominal-B, Abd-b, AbdB-I, Sab, Tab, IAB8, AbdB-II, iab5, abdominal-B, ABDB, ABD-B, DROABDB, iab, infra-abdominal 7, Miscadastral pigmentation, CG10291, Abd0B, iab-7, infra-abdominal 6, infra-abdominal 9, Superabdominal, Mc, iab7, infra-abdominal 8, BX-C, pH189, Droabdb, abdominal-b, iab9, MCP, bex, iab-8,9, Fab-7, IAB7, iab8.9, Abdb, Transabdominal, l(3)89Ed, AdbB, Fab-6, Abd B, FAB, Uab-5[Sab], IAB 5, abdB, AbdB(CA)[[26]], iab6, Mcp, iab8, infra-abdominal 5, IAB5, abdominal-A, tuh-3, Iab-7, iab-5, iab-6, infraabdominal-8.9, Fab7, Microcephalus, twig, DmAbdB, iab-8, AbdBm, CG11648, Male chauvinist pigmentation, Fab-8, infraabdominal, corset, unnamed" "IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG11648 16-Dec-15 2015_12 "ENSDARG00000042291(dlx6a),ENSDARG00000013125(dlx1a),ENSDARG00000042296(dlx5a),ENSDARG00000017174(dlx2b),ENSDARG00000014626(dlx3b),ENSDARG00000014446(dlx2a)" WBGene00000447(ceh-24) "ENSXETG00000023472(HOXC10),ENSXETG00000007580(HOXD10),ENSXETG00000000728(HOXA9)" "ENSG00000078399(HOXA9),ENSG00000180806(HOXC9),ENSG00000170689(HOXB9),ENSG00000128709(HOXD9)" " embryonic stage | late , larval stage , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , adult stage , embryonic stage | 4-10 hr , embryonic stage | 4-7 hr , embryonic stage | 10-13 hr , embryonic stage , pupal stage " " parasegment 13

, parasegment 14

, parasegment 14 &&of embryonic central nervous system

, epidermis &&of abdominal segment 9

, parasegment 10--14

, parasegment 11--13 &&of embryonic central nervous system

, parasegment 14 &&of epidermis

" " embryonic stage | mid-late , embryonic stage | mid & late , embryonic stage | stage 13 , embryonic stage | stage 12 , embryonic stage , larval stage | third instar , embryonic stage | stage 13-14 , embryonic stage | stage 11-13 , embryonic stage | stage 11 , embryonic stage | late , embryonic stage | stage >=12 , embryonic stage | stage 10 , larval stage , embryonic stage | stage >12 " " proctodeum

{ + Pc- } , ectoderm &&of parasegment 13--15

, ectoderm &&of parasegment 10--13

, visceral mesoderm

, parasegment 11--14

, ectoderm

, mesoderm &&of parasegment 11--15

, parasegment 10--14

, Malpighian tubule

, male genital disc | restricted

, female genital disc | restricted

, parasegment 13

, parasegment 12--14 &&of embryonic central nervous system

, visceral mesoderm &&of embryonic/larval hindgut &&of parasegment 13--15

, parasegment 11--15

, visceral mesoderm &&of parasegment 11--14

, embryonic dorsal vessel |posterior

, parasegment 14

, parasegment 13--15

, larval fat body | posterior

, visceral mesoderm &&of parasegment 11--13 &&of embryonic/larval midgut

, spiracle

, parasegment 11--13

, central nervous system

{ + Pc- } " "visible,homeotic,lethal,partially,recessive,female sterile,fertile,lethal - all die before end of larval stage,some die during larval stage,dominant,male sterile,male limited,mating defective,viable,female,male,somatic clone,body color defective,sterile,semi-sterile,good,cell autonomous,neuroanatomy defective,decreased cell death" "gonad,precursor,genitalia,female,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,parasegment 10,parasegment 11,parasegment 12,parasegment 13,abdominal tergite 5,male,abdominal tergite 7,abdominal sternite 6,ectopic,tergite,sternite,abdominal sternite 7,trichome,abdominal tergite 8,adult abdominal segment 6,adult abdominal segment 7,female genitalia,embryonic abdominal segment 8,abdominal 8 ventral denticle belt,posterior spiracle primordium,testis,male genitalia,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 8,embryonic/larval posterior spiracle,abdominal tergite 6,anal plate,abdominal tergite 5 & trichomeAbd-BS10),male limited,adult abdominal sensillum,abdominal sternite 5,male accessory gland secondary cell,head,adult head,terminalia,female terminalia,male terminalia,female analia,male analia,parasegment 14,embryonic abdominal segment 9,gonopod thorn bristle,mesothoracic segment,abdominal 9 ventral denticle belt,filzkorper,somatic clone,sclerite & abdominal segment 8 & embryo | somatic clone,sclerite,denticle & embryonic abdominal segment 9 | somatic clone,denticle,parasegment 9,abdominal segment 4,adult abdomen,eye,ommatidium,ocellus,occiput,head bristle,antenna,occipital bristle,frons,eye-antennal disc,scutum,adult cuticle & abdominal segment 3 | male,adult cuticle & abdominal segment 4 | male,leg,adult abdominal segment 1,genital disc primordium,adult antennal segment,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,female accessory gland,spermathecum,denticle belt,sensillum basiconicum,embryonic segment,sense organ,larval abdominal segment,anterior,adult abdominal segment 3,adult abdominal segment 2,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,spiracular sense organ (obsolete FBbt00000431),larval head,abdominal segment,prothoracic segment,metathoracic segment,tracheal system,procephalic segment,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,T1 beard,distal,arista,third segment of antenna,heart primordium,larval abdominal segment 5,larval abdominal segment 4,embryonic/larval spiracle,epiproct,abdominal segment 9,dMP2 neuron,MP1 neuron,embryonic/first instar larval cuticle,scutellar bristle,gonadal sheath proper primordium,dMP2 neuron | embryonic stage 17,MP1 neuron | embryonic stage 17,dorsal,ventral,adult mesothoracic segment,adult metathoracic segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,embryonic peripheral nervous system & embryonic abdominal segment 8,stigmatophore,cell autonomous,unguis,tibia,tarsal segment,mesothoracic tibial apical bristle,vulva,female gonopod,hypandrium,penis,clasper,second segment of antenna,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,cardioblast,embryonic/larval heart,embryonic somatic muscle,embryonic dorsal vessel,fat body/gonad primordium,wing vein,wing margin,embryonic tritocerebrum,scutellum,scutum & macrochaetaC-765,wing,gonad | embryonic stage,pretarsus,parasegment 8,trichogen cell,embryonic/larval dorsal trunk,embryonic/larval tracheal system" FBgn0033542 CG12309 http://flybase.net/reports/FBgn0033542.html protein_coding_gene 0004089=carbonate dehydratase activity "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class" CG12309 16-Dec-15 2015_12 ENSXETG00000010291(PTPRG) "viable,body color defective" mesothoracic tergum DRSC24093 IK 1.527097691 0.829892684 0.24072524 0.111083419 1.848060994 1.599467847 FBgn0032293 Dpy-30L1 Dpy-30-like 1 http://flybase.net/reports/FBgn0032293.html protein_coding_gene "0046331=lateral inhibition, 0051568=histone H3-K4 methylation" "0048188=Set1C/COMPASS complex, 0044665=MLL1/2 complex, 0044666=MLL3/4 complex" "Dpy-30L1, DPY30, Dpy30, Dpy-30-like 1, dpy30, CG6444, dDPY30-L1, dpy-30L1" IPR007858=Dpy-30 motif CG6444 16-Dec-15 2015_12 ENSDARG00000004427(dpy30) YDR469W(SDC1) WBGene00001088(dpy-30) "chemical sensitive,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0030437 hec hector http://flybase.net/reports/FBgn0030437.html "FBgn0046551, FBgn0046625" protein_coding_gene "0004948=calcitonin receptor activity, 0008188=neuropeptide receptor activity" "0008049=male courtship behavior, 0007186=G-protein coupled receptor signaling pathway" 0016021=integral component of membrane "CG4395, Hector, anon-WO0170980.2, anon-WO0170980.1" "IPR017981=GPCR, family 2-like, IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR003287=GPCR, family 2, calcitonin receptor family, IPR017983=GPCR, family 2, secretin-like, conserved site, IPR000832=GPCR, family 2, secretin-like" CG4395 16-Dec-15 2015_12 "mating behavior defective,male limited,viable" FBgn0261564 Reep1 REEP1 homolog http://flybase.net/reports/FBgn0261564.html "FBgn0050193, FBgn0062236, FBgn0062456, FBgn0064893, FBgn0050190, FBgn0034799" protein_coding_gene 0034976=response to endoplasmic reticulum stress 0005783=endoplasmic reticulum "reep1, BcDNA:RE29641, CG30193, CG30190, BcDNA:LD42159, CG9848, CG42678, D-reep1, anon-WO0118547.113" IPR004345=TB2/DP1/HVA22-related protein CG42678 16-Dec-15 2015_12 "ENSDARG00000031382(zgc:110128),ENSDARG00000014854(LOC799901),ENSDARG00000017569(reep3l),ENSDARG00000004160(reep3)" WBGene00020562(T19C3.4) "ENSMUSG00000038555(Reep2),ENSMUSG00000052852(Reep1),ENSMUSG00000033589(Reep4),ENSMUSG00000019873(Reep3)" "ENSG00000068615(REEP1),ENSG00000132563(REEP2),ENSG00000168476(REEP4),ENSG00000165476(REEP3)" FBgn0267236 CG45676 http://flybase.net/reports/FBgn0267236.html protein_coding_gene CG45676 16-Dec-15 2015_12 FBgn0267807 CR46132 http://flybase.net/reports/FBgn0267807.html non_protein_coding_gene CR46132 16-Dec-15 2015_12 FBgn0038478 cal1 chromosome alignment defect 1 http://flybase.net/reports/FBgn0038478.html protein_coding_gene "0005515=protein binding, 0030674=protein binding, bridging, 0042393=histone binding" "0016321=female meiosis chromosome segregation, 0007052=mitotic spindle organization, 0000278=mitotic cell cycle, 0090234=regulation of kinetochore assembly, 1903099=positive regulation of CENP-A containing nucleosome assembly, 0071459=protein localization to chromosome, centromeric region, 0034501=protein localization to kinetochore" "0000776=kinetochore, 0000775=chromosome, centromeric region, 0005730=nucleolus" "CAL1, Cal1, CG5148, CLD2, Chromosome alignment defect 1" "IPR003903=Ubiquitin interacting motif, IPR018465=Centromere protein Scm3/HJURP" CG5148 16-Dec-15 2015_12 "neuroanatomy defective,recessive,meiotic cell cycle defective,semidominant,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,lethal,mitotic cell cycle defective" "nucleus,embryonic/larval central nervous system,presumptive embryonic/larval central nervous system,trichogen cell,mesothoracic tergum" FBgn0024142 Bip-p15 Bcd interacting protein p15 http://flybase.net/reports/FBgn0024142.html gene p15 16-Dec-15 2015_12 FBgn0037512 CG2616 http://flybase.net/reports/FBgn0037512.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG2616 16-Dec-15 2015_12 "ENSDARG00000015856(slc25a40),ENSDARG00000007449(slc25a39)" YGR257C(MTM1) WBGene00007622(C16C10.1) "ENSXETG00000027655(BC075453.1),ENSXETG00000011613(BC088076.1)" "ENSMUSG00000054099(Slc25a40),ENSMUSG00000018677(Slc25a39)" "ENSG00000075303(SLC25A40),ENSG00000013306(SLC25A39)" viable FBgn0259642 B2036 http://flybase.net/reports/FBgn0259642.html gene 16-Dec-15 2015_12 visible "submarginal cell,anterior crossvein,wing vein L3,wing vein" FBgn0000226 bsc bent scutellars http://flybase.net/reports/FBgn0000226.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,poor,fertile,reduced,male fertile" "scutellar bristle,eye,wing,macrochaeta" FBgn0046769 CG32331 http://flybase.net/reports/FBgn0046769.html FBgn0052331 protein_coding_gene BcDNA:LD40851 16-Dec-15 2015_12 DRSC21332 I -0.404863425 -1.878941061 0.031248613 0.512350503 -1.200168432 0.586933741 FBgn0265214 fs(2)Z2-3774 http://flybase.net/reports/FBgn0265214.html gene 16-Dec-15 2015_12 female sterile FBgn0005250 l(3)R340 lethal of Roberts 340 http://flybase.net/reports/FBgn0005250.html gene l(3)340 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003199 rai raisin http://flybase.net/reports/FBgn0003199.html gene 16-Dec-15 2015_12 "eye color defective,recessive,visible" pigment cell FBgn0005683 pie pineapple eye http://flybase.net/reports/FBgn0005683.html "FBgn0002088, FBgn0002668, FBgn0032245" protein_coding_gene 0008270=zinc ion binding "0022008=neurogenesis, 0042078=germ-line stem cell division, 0035019=somatic stem cell maintenance, 0036335=intestinal stem cell homeostasis, 0048749=compound eye development" "mat(2)QM47, l(2)54, lethal(2)54, mat(2)earlyQM47, rumpled, maternal effect early arrest E, Pineapple eye, mat(2)ea-E, CG5354, l(2)31Ek" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR001965=Zinc finger, PHD-type" CG5354 16-Dec-15 2015_12 ENSDARG00000001313(g2e3) "lethal,sterile,recessive,developmental rate defective,partially lethal - majority die,female sterile,male semi-sterile,viable,increased cell death,somatic clone,partially lethal - majority live,visible,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,neuroanatomy defective,female fertile" "eye,ommatidium,somatic clone,photoreceptor cell,cone cell,pigment cell,eye photoreceptor cell,ventral thoracic disc,wing disc,eye disc,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0029840 raptor raptor http://flybase.net/reports/FBgn0029840.html protein_coding_gene "0007411=axon guidance, 0007517=muscle organ development, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0040018=positive regulation of multicellular organism growth, 0007562=eclosion, 0001934=positive regulation of protein phosphorylation, 0008340=determination of adult lifespan, 0031929=TOR signaling, 0048477=oogenesis, 0006974=cellular response to DNA damage stimulus" 0031931=TORC1 complex "CG4320, dRaptor, raptor/CG4320, dRap, 4320, target of rapamycin (TOR)-associated protein, RAPTOR, Raptor" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR016024=Armadillo-type fold, IPR017986=WD40-repeat-containing domain, IPR004083=Regulatory associated protein of TOR, IPR001680=WD40 repeat, IPR029347=Raptor N-terminal CASPase-like domain, IPR011989=Armadillo-like helical" CG4320 16-Dec-15 2015_12 YHR186C(KOG1) WBGene00000911(daf-15) ENSXETG00000013410(RPTOR) ENSMUSG00000025583(Rptor) ENSG00000141564(RPTOR) "neuroanatomy defective,size defective,decreased cell size,decreased cell number,visible,lethal" "NMJ bouton | third instar larval stage,wing" DRSC18359 I -1.306402847 3.25450797 -0.59535879 -0.035422718 -0.131587717 0.80808625 FBgn0065359 l(2)SH1750 lethal (2) SH1750 http://flybase.net/reports/FBgn0065359.html gene l(2)SH2 1750 16-Dec-15 2015_12 "lethal,recessive" FBgn0010366 anon-32D anon-32D http://flybase.net/reports/FBgn0010366.html gene Ubx-t9 16-Dec-15 2015_12 FBgn0085744 CR40561 http://flybase.net/reports/FBgn0085744.html FBan0040561 rRNA_gene CR40561 16-Dec-15 2015_12 FBgn0263742 CG43667 http://flybase.net/reports/FBgn0263742.html FBgn0034550 protein_coding_gene CG15226 CG43667 16-Dec-15 2015_12 FBgn0013305 Nmda1 N-methyl-D-aspartate receptor-associated protein http://flybase.net/reports/FBgn0013305.html protein_coding_gene 0004972=N-methyl-D-aspartate selective glutamate receptor activity 0017146=N-methyl-D-aspartate selective glutamate receptor complex "DRONMDA, dNMDARA1, NMDARA1, CG3798, cDNA2, dTmbim3, NMDARA1-like" IPR006214=Bax inhibitor 1-related CG3798 16-Dec-15 2015_12 ENSDARG00000055138(zgc:110410) YNL305C() "WBGene00009580(xbx-6),WBGene00006470(tag-120)" "ENSXETG00000014916(TMBIM1),ENSXETG00000020393(FAIM2)" ENSMUSG00000022564(Grina) ENSG00000178719(GRINA) viable heart primordium FBgn0001863 l(1)VE807 lethal (1) VE807 http://flybase.net/reports/FBgn0001863.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005404 l(1)10Cg lethal (1) 10Cg http://flybase.net/reports/FBgn0005404.html gene 16-Dec-15 2015_12 lethal FBgn0065778 l(2)SH0447 lethal (2) SH0447 http://flybase.net/reports/FBgn0065778.html gene l(2)SH2 0447 16-Dec-15 2015_12 "lethal,recessive" FBgn0036836 CG11619 http://flybase.net/reports/FBgn0036836.html protein_coding_gene "2001070=starch binding, 0008081=phosphoric diester hydrolase activity" 0006629=lipid metabolic process "IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR013784=Carbohydrate-binding-like fold, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR002044=Carbohydrate binding module family 20, IPR013783=Immunoglobulin-like fold, IPR030395=Glycerophosphodiester phosphodiesterase domain" CG11619 16-Dec-15 2015_12 viable DRSC09849 K 1.015241888 0.700768109 -0.061673317 -0.199184474 0.017372658 1.674695605 FBgn0032298 CG6724 http://flybase.net/reports/FBgn0032298.html protein_coding_gene "0022008=neurogenesis, 0000463=maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" "0070545=PeBoW complex, 0005829=cytosol, 0005886=plasma membrane" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR012972=NLE, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR028599=WD repeat WDR12/Ytm1, IPR019775=WD40 repeat, conserved site" CG6724 16-Dec-15 2015_12 ENSDARG00000003287(wdr12) YOR272W(YTM1) WBGene00018893(tag-345) ENSXETG00000022077(wdr12) ENSMUSG00000026019(Wdr12) ENSG00000138442(WDR12) "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0033701 CG13171 http://flybase.net/reports/FBgn0033701.html protein_coding_gene CG13171 16-Dec-15 2015_12 viable FBgn0002108 l(2)85 lethal (2) 85 http://flybase.net/reports/FBgn0002108.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036975 CG5618 http://flybase.net/reports/FBgn0036975.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0004782=sulfinoalanine decarboxylase activity" 0019752=carboxylic acid metabolic process "IPR015424=Pyridoxal phosphate-dependent transferase, IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2" CG5618 16-Dec-15 2015_12 "viable,fertile" FBgn0031552 CG15416 http://flybase.net/reports/FBgn0031552.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262680 CR43150 http://flybase.net/reports/FBgn0262680.html non_protein_coding_gene "CG43150, mdcds_33995" CR43150 16-Dec-15 2015_12 FBgn0069444 E(br)65 E(br)65 http://flybase.net/reports/FBgn0069444.html gene "0007391=dorsal closure, 0008258=head involution" 16-Dec-15 2015_12 "lethal,recessive" "embryonic/first instar larval cuticle,anterior" FBgn0002739 mgt midget http://flybase.net/reports/FBgn0002739.html gene 16-Dec-15 2015_12 "viable,male,reduced,female,male fertile,visible,recessive" FBgn0045048 fs(1)260 female sterile (1) 260 http://flybase.net/reports/FBgn0045048.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "ovary,border follicle cell,nurse cell,supernumerary" FBgn0082319 LpR2::Mmus\Egf Egf http://flybase.net/reports/FBgn0082319.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0005168 l(2)G563 lethal (2) G563 http://flybase.net/reports/FBgn0005168.html gene 16-Dec-15 2015_12 lethal FBgn0035033 CG3548 http://flybase.net/reports/FBgn0035033.html protein_coding_gene IPR028002=Myb/SANT-like DNA-binding domain CG3548 16-Dec-15 2015_12 "viable,fertile" DRSC04387 E 0.949498679 0.40933099 1.91603909 -1.686024417 -0.649097544 -0.461686586 FBgn0065347 l(2)SH1811 lethal (2) SH1811 http://flybase.net/reports/FBgn0065347.html gene l(2)SH2 1811 16-Dec-15 2015_12 "lethal,recessive" FBgn0041721 snRNA:U12:73B snRNA:U12:73B http://flybase.net/reports/FBgn0041721.html "FBgn0046354, FBgn0052162" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005693=U12 snRNP "73B U12, U12, anon-WO0172774.79, CR32162, U12:73B, dU12" CR32162 16-Dec-15 2015_12 "lethal,recessive" FBgn0028884 CG4892 http://flybase.net/reports/FBgn0028884.html FBgn0063712 protein_coding_gene "BG:DS04095.2, DS04095.2, BcDNA:AT24169" IPR026806=Protein CDV3 CG4892 16-Dec-15 2015_12 "viable,fertile" DRSC01937 I 1.723887641 -0.431798428 -1.093632781 0.258722026 0.270787918 0.086115712 FBgn0043869 nompJ no mechanoreceptor potential J http://flybase.net/reports/FBgn0043869.html gene 0007605=sensory perception of sound 16-Dec-15 2015_12 "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0060952 l(3)S036901b lethal (3) S036901b http://flybase.net/reports/FBgn0060952.html gene 0369/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0260273 GSd213 http://flybase.net/reports/FBgn0260273.html gene 16-Dec-15 2015_12 lethal FBgn0014315 l(3)ry116 lethal (3) ry116 http://flybase.net/reports/FBgn0014315.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083039 snoRNA:ë¬18S-301 snoRNA:ë¬18S-301 http://flybase.net/reports/FBgn0083039.html snoRNA_gene "Psi 18S-301, chr3R:16400618..16400867, CR34614, psi18s-301" CR34614 16-Dec-15 2015_12 FBgn0065570 l(2)SH0970 lethal (2) SH0970 http://flybase.net/reports/FBgn0065570.html gene l(2)SH2 0970 16-Dec-15 2015_12 "lethal,recessive" FBgn0014372 pll::tor pll::tor http://flybase.net/reports/FBgn0014372.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0283464 mir-4966-2 mir-4966-2 stem loop http://flybase.net/reports/FBgn0283464.html miRNA_gene dme-mir-4966-2 16-Dec-15 2015_12 FBgn0087018 l(3)61Df lethal (3) 61Df http://flybase.net/reports/FBgn0087018.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die" FBgn0035262 CG18171 http://flybase.net/reports/FBgn0035262.html protein_coding_gene CG18171 16-Dec-15 2015_12 viable FBgn0036205 CG14131 http://flybase.net/reports/FBgn0036205.html protein_coding_gene Pi3K68D CG14131 16-Dec-15 2015_12 viable FBgn0050208 tRNA:CR30208 transfer RNA:CR30208 http://flybase.net/reports/FBgn0050208.html FBgn0060017 tRNA_gene 0033416=UGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna45-TrpCCA, CR30208, AE002575.trna1-TrpCCA, tRNA:W:CCA:AE002575-a" CR30208 16-Dec-15 2015_12 FBgn0004037 yea3 yeast 3 http://flybase.net/reports/FBgn0004037.html gene 16-Dec-15 2015_12 FBgn0267560 CR45900 http://flybase.net/reports/FBgn0267560.html non_protein_coding_gene CR45900 16-Dec-15 2015_12 FBgn0259650 B1521 http://flybase.net/reports/FBgn0259650.html gene 16-Dec-15 2015_12 visible "chaeta,ectopic,wing,distal" FBgn0058274 CG40274 http://flybase.net/reports/FBgn0058274.html protein_coding_gene 16-Dec-15 2015_12 DRSC21725 K -0.45427785 0.510755802 -0.24317685 0.259994663 1.652206491 0.687832454 FBgn0085341 CG34312 http://flybase.net/reports/FBgn0085341.html protein_coding_gene CG34312 16-Dec-15 2015_12 FBgn0028035 l(3)S101310 lethal (3) S101310 http://flybase.net/reports/FBgn0028035.html gene 1013/10 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0036678 CG11905 http://flybase.net/reports/FBgn0036678.html protein_coding_gene 0005875=microtubule associated complex CG11905 16-Dec-15 2015_12 viable FBgn0002105 l(2)57Eb lethal (2) 57Eb http://flybase.net/reports/FBgn0002105.html gene l(2)57DEFb 16-Dec-15 2015_12 "lethal,recessive" FBgn0010903 l(3)06811 lethal (3) 06811 http://flybase.net/reports/FBgn0010903.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015623 Cpr Cytochrome P450 reductase http://flybase.net/reports/FBgn0015623.html protein_coding_gene "0016709=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, 0010181=FMN binding, 0003958=NADPH-hemoprotein reductase activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0005783=endoplasmic reticulum, 0005811=lipid particle, 0012505=endomembrane system, 0005829=cytosol" "cpr, Cytochrome c reductase (NADPH), CG11567, NADPH-cytochrome P450 oxidoreductase, P450, cytochrome P450 reductase, P450 reductase, NCPR, CCR, NADPH-cytochrome P450 reductase, DMR, CPR, NADPH--ferrihemoprotein reductase; NADPH-cytochrome P450 reductase, DmCPR" "IPR008254=Flavodoxin/nitric oxide synthase, IPR001433=Oxidoreductase FAD/NAD(P)-binding, IPR001709=Flavoprotein pyridine nucleotide cytochrome reductase, IPR001094=Flavodoxin, IPR023208=NADPH-cytochrome P450 reductase, IPR003097=FAD-binding, type 1, IPR023173=NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3, IPR029039=Flavoprotein-like, IPR017938=Riboflavin synthase-like beta-barrel, IPR017927=Ferredoxin reductase-type FAD-binding domain" CG11567 16-Dec-15 2015_12 "ENSDARG00000059035(zgc:63480),ENSDARG00000055092(por)" YHR042W(NCP1) WBGene00001262(emb-8) ENSXETG00000008983(POR) ENSMUSG00000005514(Por) ENSG00000127948(POR) " embryonic stage , adult stage " antenna

"lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0082336 HM745 HM745 http://flybase.net/reports/FBgn0082336.html gene 16-Dec-15 2015_12 FBgn0024641 l(2)k12602 lethal (2) k12602 http://flybase.net/reports/FBgn0024641.html gene 126/2 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0013502 l(1)PB2 lethal (1) PB2 http://flybase.net/reports/FBgn0013502.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg" FBgn0024309 SM-20d Similar to rat Smooth Muscle-20 http://flybase.net/reports/FBgn0024309.html gene SM-20 16-Dec-15 2015_12 FBgn0028950 CG15255 http://flybase.net/reports/FBgn0028950.html protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" "0022008=neurogenesis, 0006508=proteolysis" BG:BACR44L22.1 "IPR001506=Peptidase M12A, astacin, IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain" CG15255 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0000834 fs(1)M17 female sterile (1) M17 http://flybase.net/reports/FBgn0000834.html gene 16-Dec-15 2015_12 "lethal,maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,maternal effect" FBgn0013602 l(3)B9-3-53 lethal (3) B9-3-53 http://flybase.net/reports/FBgn0013602.html gene 16-Dec-15 2015_12 lethal FBgn0260636 l(3)72-73a http://flybase.net/reports/FBgn0260636.html FBgn0016902 gene "72CDd, l(3)72CDd" 16-Dec-15 2015_12 lethal FBgn0060505 l(3)S104913a lethal (3) S104913a http://flybase.net/reports/FBgn0060505.html gene 1049/13 16-Dec-15 2015_12 lethal FBgn0264720 CR43988 http://flybase.net/reports/FBgn0264720.html non_protein_coding_gene lincRNA.397 CR43988 16-Dec-15 2015_12 FBgn0264878 CR44069 http://flybase.net/reports/FBgn0264878.html non_protein_coding_gene CR44069 16-Dec-15 2015_12 FBgn0261632 CR42715 http://flybase.net/reports/FBgn0261632.html non_protein_coding_gene "mdcds_11421, mdcds_11422, CG42715" CR42715 16-Dec-15 2015_12 FBgn0259877 cid::His3 http://flybase.net/reports/FBgn0259877.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0051267 CG31267 http://flybase.net/reports/FBgn0051267.html FBgn0038483 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH146, CG5240" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG31267 16-Dec-15 2015_12 viable FBgn0039592 CG14062 http://flybase.net/reports/FBgn0039592.html protein_coding_gene "0046872=metal ion binding, 0016787=hydrolase activity, 0003676=nucleic acid binding" LP23408p "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG14062 16-Dec-15 2015_12 "ENSDARG00000063613,ENSDARG00000071216,ENSDARG00000071224(si:ch211-133n4.4),ENSDARG00000071223(zgc:158445),ENSDARG00000063044,ENSDARG00000068523,ENSDARG00000069190(zgc:172339),ENSDARG00000068065,ENSDARG00000061611(LOC556323),ENSDARG00000060913,ENSDARG00000061822,ENSDARG00000070242(zgc:171534)" viable FBgn0002882 mus106 mutagen-sensitive 106 http://flybase.net/reports/FBgn0002882.html gene "mus-106, mus(1)106" 16-Dec-15 2015_12 "chemical sensitive,DNA repair defective,recessive,radiation sensitive,female sterile" FBgn0001461 l(1)7Eb lethal (1) 7Eb http://flybase.net/reports/FBgn0001461.html gene JA4 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0267657 CR45995 http://flybase.net/reports/FBgn0267657.html non_protein_coding_gene CR45995 16-Dec-15 2015_12 FBgn0262565 CR43105 http://flybase.net/reports/FBgn0262565.html pseudogene_attribute CG43105 CR43105 16-Dec-15 2015_12 FBgn0013763 CG5210 http://flybase.net/reports/FBgn0013763.html protein_coding_gene "0004568=chitinase activity, 0008061=chitin binding" "0006032=chitin catabolic process, 0006036=cuticle chitin catabolic process, 0005975=carbohydrate metabolic process" "0005576=extracellular region, 0005615=extracellular space" "chit, ds47, Chit, Chitinase-like, chitinase-like, DS47, Cht13, DmDS47, CG5210, Chit13" "IPR011583=Chitinase II, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR029070=Chitinase insertion domain, IPR017853=Glycoside hydrolase superfamily, IPR015520=Imaginal disc growth factor" CG5210 16-Dec-15 2015_12 YDR371W(CTS2) " larval stage , embryonic stage&&larval stage , adult stage | male , adult stage | female " " embryonic/larval fat body

, hemolymph

" " larval stage , embryonic stage -- adult stage " " embryonic/larval fat body

, hemolymph

" viable DRSC07360 K -0.016641266 0.56892805 -0.172799061 0.032153275 -1.558531472 0.189659516 FBgn0086389 BG01803 http://flybase.net/reports/FBgn0086389.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0032486 CG5705 http://flybase.net/reports/FBgn0032486.html protein_coding_gene "0016149=translation release factor activity, codon specific" 0006415=translational termination 0005739=mitochondrion "IPR005139=Peptide chain release factor, IPR014720=Double-stranded RNA-binding domain, IPR000352=Peptide chain release factor class I/class II" CG5705 16-Dec-15 2015_12 ENSDARG00000060005(mtrf1l) YGL143C(MRF1) WBGene00020993(W03F8.3) "ENSXETG00000018541(MTRF1L),ENSXETG00000018904(MTRF1)" "ENSMUSG00000019774(Mtrf1l),ENSMUSG00000022022(Mtrf1)" "ENSG00000112031(MTRF1L),ENSG00000180015,ENSG00000120662(MTRF1)" viable FBgn0025342 anon-58Fa anon-58Fa http://flybase.net/reports/FBgn0025342.html gene K3 16-Dec-15 2015_12 FBgn0044118 E(rst)B94 E(rst)B94 http://flybase.net/reports/FBgn0044118.html gene 0001745=compound eye morphogenesis B94 16-Dec-15 2015_12 "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0267183 CR45623 http://flybase.net/reports/FBgn0267183.html non_protein_coding_gene CR45623 16-Dec-15 2015_12 FBgn0016714 Reg-19 Rhythmically expressed gene 19 http://flybase.net/reports/FBgn0016714.html gene "Dreg-19, Drosophila Rhythmically expressed gene 19" 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0004927 l(3)dco2 lethal (3) discs overgrown 2 http://flybase.net/reports/FBgn0004927.html gene l(3)dco-2 16-Dec-15 2015_12 lethal FBgn0013736 stld stalled http://flybase.net/reports/FBgn0013736.html gene 0007625=grooming behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0065801 l(2)SH0408 lethal (2) SH0408 http://flybase.net/reports/FBgn0065801.html gene l(2)SH2 0408 16-Dec-15 2015_12 "lethal,recessive" FBgn0046634 anon-38E.18 anon-38E.18 http://flybase.net/reports/FBgn0046634.html gene 38E.18 16-Dec-15 2015_12 FBgn0262451 ban bantam http://flybase.net/reports/FBgn0262451.html "FBgn0064191, FBgn0043352, FBgn0262311" miRNA_gene 0003730=mRNA 3'-UTR binding "0030718=germ-line stem cell maintenance, 0017148=negative regulation of translation, 0040018=positive regulation of multicellular organism growth, 0035195=gene silencing by miRNA, 2000648=positive regulation of stem cell proliferation, 0045927=positive regulation of growth, 0001654=eye development, 0035278=negative regulation of translation involved in gene silencing by miRNA, 0071481=cellular response to X-ray, 0031104=dendrite regeneration, 0046716=muscle cell cellular homeostasis, 0050773=regulation of dendrite development, 0042981=regulation of apoptotic process, 0040014=regulation of multicellular organism growth, 0008283=cell proliferation, 0043066=negative regulation of apoptotic process, 2001233=regulation of apoptotic signaling pathway, 0060288=formation of a compartment boundary, 0008284=positive regulation of cell proliferation, 0060968=regulation of gene silencing, 0042127=regulation of cell proliferation, 0016049=cell growth, 0008101=decapentaplegic signaling pathway, 0035329=hippo signaling" "cot, pri-bantam, CR43018, mIR-bantam, Bantam, CR33559, miR-ban, clochette, miR-bantam, dme-bantam, EP3208, unnamed, bantam" CR43018 16-Dec-15 2015_12 " embryonic stage -- adult stage , larval stage " " organism

, brain

restricted , dorsal mesothoracic disc

" FBgn0025120 su(RpII140Z36)S8 su(RpII140Z36)S8 http://flybase.net/reports/FBgn0025120.html gene Z36[S8] 16-Dec-15 2015_12 FBgn0041140 l(2)44Da lethal (2) 44Da http://flybase.net/reports/FBgn0041140.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001115 gm gleam http://flybase.net/reports/FBgn0001115.html gene 16-Dec-15 2015_12 "visible,viable,reduced" "eye,ommatidium,interommatidial bristle" FBgn0014201 l(1)16Fh lethal (1) 16Fh http://flybase.net/reports/FBgn0014201.html gene HL-XI 16-Dec-15 2015_12 FBgn0038325 Atg4b Autophagy-related 4b http://flybase.net/reports/FBgn0038325.html protein_coding_gene 0004197=cysteine-type endopeptidase activity "0006508=proteolysis, 0006914=autophagy, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" 0005829=cytosol "Autophagy-specific gene 4b, Atg4b, CG6194, DmAtg4-like, AUT2, APG4, Atg4" IPR005078=Peptidase C54 CG6194 16-Dec-15 2015_12 "ENSDARG00000043548(LOC795933),ENSDARG00000044373(atg4c)" YNL223W(ATG4) WBGene00014080(atg-4.2) "ENSXETG00000011644(apg4d),ENSXETG00000010838(apg4c)" "ENSMUSG00000002820(Atg4d),ENSMUSG00000028550(Atg4c)" "ENSG00000130734(ATG4D),ENSG00000125703(ATG4C)" pupal stage salivary gland

"viable,visible,fertile" "chaeta,supernumerary,trichogen cell" FBgn0039710 dgt1 dim ë_-tubulin 1 http://flybase.net/reports/FBgn0039710.html protein_coding_gene "0022008=neurogenesis, 0007095=mitotic G2 DNA damage checkpoint" "0005634=nucleus, 0044545=NSL complex" "CG18041, non-specific lethal 2, Dgt1, NSL2, dim gamma-tubulin 1" "IPR026316=KAT8 regulatory NSL complex subunit 2, IPR025927=Potential DNA-binding domain" CG18041 16-Dec-15 2015_12 ENSDARG00000056318(zgc:103534) ENSXETG00000009782(C12orf41) "ENSMUSG00000070035,ENSMUSG00000022992(2310037I24Rik)" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC15301 E -0.546845495 -0.339042802 -0.497507385 -3.34504605 -0.951560735 -1.015911756 FBgn0035149 MED30 Mediator complex subunit 30 http://flybase.net/reports/FBgn0035149.html FBgn0063484 protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity 0006357=regulation of transcription from RNA polymerase II promoter "0005634=nucleus, 0016592=mediator complex" "CG17183, Med30, dMED20, med30, Med11/TRAP25, Trap25, Med20, dTRAP25" "IPR021019=Mediator complex, subunit Med30, metazoa" CG17183 16-Dec-15 2015_12 "ENSDARG00000035725,ENSDARG00000029459(thrap6)" ENSXETG00000020788(MED30) ENSG00000164758(MED30) "viable,visible" "trichogen cell,tormogen cell" DRSC30026 K 1.396496184 1.619990061 FBgn0039780 PH4ë±NE1 prolyl-4-hydroxylase-alpha NE1 http://flybase.net/reports/FBgn0039780.html protein_coding_gene "0005506=iron ion binding, 0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" CG9728 "IPR011990=Tetratricopeptide-like helical domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123=Oxoglutarate/iron-dependent dioxygenase" CG9728 16-Dec-15 2015_12 viable FBgn0036467 CG12310 http://flybase.net/reports/FBgn0036467.html FBgn0047184 protein_coding_gene "chr3L:15015907..15016009, BcDNA:RE02926" CG12310 16-Dec-15 2015_12 viable FBgn0001568 soz sozzled http://flybase.net/reports/FBgn0001568.html gene "A72, EA41, l(1)HM41, l(1)20Bb" 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,viable" FBgn0005001 cu-X curled on X http://flybase.net/reports/FBgn0005001.html gene curled-X 16-Dec-15 2015_12 "visible,male" "wing,male" FBgn0283473 S6KL S6 Kinase Like http://flybase.net/reports/FBgn0283473.html "FBgn0004462, FBgn0024489, FBgn0024143" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation 0005737=cytoplasm "Pk?4, CG7001, Bcd interacting protein K, 3-10, pk17e, Bicoid interacting protein 4, Protein kinase-like 17E, Bin4, Pk17E, bin4, BcdK, BIN4" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG7001 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective" anterior fascicle & synapse DRSC23147 K -0.728183635 -0.183412265 -0.101875161 0.511737199 -2.874983619 0.361835384 FBgn0051244 CG31244 http://flybase.net/reports/FBgn0051244.html FBgn0038703 protein_coding_gene 0008157=protein phosphatase 1 binding CG18491 "IPR029072=YebC-like, IPR002876=Transcriptional regulator TACO1-like" CG31244 16-Dec-15 2015_12 FBgn0263215 CR43385 http://flybase.net/reports/FBgn0263215.html pseudogene_attribute CR43385 16-Dec-15 2015_12 FBgn0024879 l(2)52Fb lethal (2) 52Fb http://flybase.net/reports/FBgn0024879.html gene D2.33 16-Dec-15 2015_12 lethal FBgn0259318 EP-64 http://flybase.net/reports/FBgn0259318.html gene 16-Dec-15 2015_12 visible "wing,chaeta,ectopic" FBgn0262771 Su(E1)-E http://flybase.net/reports/FBgn0262771.html gene 16-Dec-15 2015_12 FBgn0261983 l(2)gd1 lethal (2) giant discs 1 http://flybase.net/reports/FBgn0261983.html "FBgn0250747, FBgn0002119, FBgn0032342, FBgn0065753" protein_coding_gene 0005543=phospholipid binding "0048132=female germ-line stem cell asymmetric division, 0008586=imaginal disc-derived wing vein morphogenesis, 0006886=intracellular protein transport, 0048749=compound eye development, 0045732=positive regulation of protein catabolic process, 0016197=endosomal transport, 0030100=regulation of endocytosis, 0007472=wing disc morphogenesis, 0000281=mitotic cytokinesis, 0008593=regulation of Notch signaling pathway, 0045746=negative regulation of Notch signaling pathway, 0007423=sensory organ development, 0036257=multivesicular body organization, 0045035=sensory organ precursor cell division" "0016324=apical plasma membrane, 0005737=cytoplasm" "l(2)gd, Leathal giant disc, lethal (2) SH0495, l(2)SH2 0495, lgd, lethal (2) giant discs, gd, lethal giant discs, l(2)SH0495, CG4713, SH495, l[[2]]gd, l(2)giant disc" "IPR006608=Domain of unknown function DM14, IPR000008=C2 domain" CG4713 16-Dec-15 2015_12 WBGene00012578(Y37H9A.3) "ENSXETG00000008058(CC2D1B),ENSXETG00000005556(CC2D1A)" "ENSMUSG00000028582(Cc2d1b),ENSMUSG00000036686(Cc2d1a)" "ENSG00000154222(CC2D1B),ENSG00000132024(CC2D1A)" FBgn0263529 mir-4977 mir-4977 stem loop http://flybase.net/reports/FBgn0263529.html miRNA_gene "CR43514, dme-mir-4977" CR43514 16-Dec-15 2015_12 FBgn0016910 l(3)X4 lethal (3) X4 http://flybase.net/reports/FBgn0016910.html gene X4 16-Dec-15 2015_12 FBgn0020366 anon-10Ea anon-10Ea http://flybase.net/reports/FBgn0020366.html gene "9H9, unnamed" 16-Dec-15 2015_12 FBgn0265997 CR44772 http://flybase.net/reports/FBgn0265997.html non_protein_coding_gene lincRNA.19 CR44772 16-Dec-15 2015_12 FBgn0266901 CR45361 http://flybase.net/reports/FBgn0266901.html non_protein_coding_gene pri-mir-1 CR45361 16-Dec-15 2015_12 FBgn0027574 CG5815 http://flybase.net/reports/FBgn0027574.html protein_coding_gene "0035091=phosphatidylinositol binding, 0004630=phospholipase D activity" "0030334=regulation of cell migration, 0006654=phosphatidic acid biosynthetic process, 0050764=regulation of phagocytosis, 0048017=inositol lipid-mediated signaling" "BcDNA:GH07089, BcDNA:GH07346, Spt2" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR013256=Chromatin SPT2, IPR001683=Phox homologous domain, IPR016555=Phospholipase D1/D2, IPR015679=Phospholipase D family, IPR001736=Phospholipase D/Transphosphatidylase, IPR025202=Phospholipase D-like domain" CG5815 16-Dec-15 2015_12 ENSDARG00000033889(spty2d1) ENSMUSG00000049516(Spty2d1) ENSG00000179119(SPTY2D1) viable FBgn0283440 solo sisters on the loose http://flybase.net/reports/FBgn0283440.html "FBgn0262526, FBgn0004805, FBgn0028928, FBgn0053678" protein_coding_gene 0043221=SMC family protein binding "0071921=cohesin localization to chromatin, 0070193=synaptonemal complex organization, 0051754=meiotic sister chromatid cohesion, centromeric, 0007143=female meiotic division" "0000795=synaptonemal complex, 0000775=chromosome, centromeric region" "BG:DS00929.15, CG43081, CG33678, no-relish, pf7, fs(2)ltoRJ36, courgette, cgt, CG46282, female sterile(2)ltoRJ36" CG46282 16-Dec-15 2015_12 "viable,female sterile" FBgn0046651 anon-38D.13 anon-38D.13 http://flybase.net/reports/FBgn0046651.html gene 38D.13 16-Dec-15 2015_12 FBgn0045845 mdg1\sORF2 sORF2 http://flybase.net/reports/FBgn0045845.html transposable_element_gene sORF 16-Dec-15 2015_12 FBgn0002833 ms(2)E12 male sterile (2) E12 http://flybase.net/reports/FBgn0002833.html gene "ms(2)2.12, ms2.12" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0037377 CG1218 http://flybase.net/reports/FBgn0037377.html protein_coding_gene "0008270=zinc ion binding, 0072572=poly-ADP-D-ribose binding" "IPR019406=Zinc finger, C2H2, APLF-like, IPR019361=Protein of unknown function DUF2228, C2H2, APLF-like" CG1218 16-Dec-15 2015_12 ENSDARG00000057114(zgc:101819) WBGene00010439(JC8.7) ENSXETG00000023145(C4orf27) ENSMUSG00000038005(2700029M09Rik) ENSG00000056050(C4orf27) viable FBgn0022314 l(1)D47.6 lethal (1) D47.6 http://flybase.net/reports/FBgn0022314.html gene D47.6 16-Dec-15 2015_12 "lethal,recessive" FBgn0053426 5SrRNA:CR33426 5SrRNA:CR33426 http://flybase.net/reports/FBgn0053426.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33426 CR33426 16-Dec-15 2015_12 FBgn0050134 CR30134 http://flybase.net/reports/FBgn0050134.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0046873 Pif2 PFTAIRE-interacting factor 2 http://flybase.net/reports/FBgn0046873.html "FBgn0045982, FBgn0046005, FBgn0046023, FBgn0046028, FBgn0046039, FBgn0051483, FBgn0063706" protein_coding_gene 0005515=protein binding "NEST:bs19e11, NEST:bs25a03, NEST:bs18a02, CG31483, bs20e01.y1, BcDNA:AT26658, PIF-2, NEST:bs20e01, NEST:bs35g11" CG31483 16-Dec-15 2015_12 FBgn0265306 CR44279 http://flybase.net/reports/FBgn0265306.html non_protein_coding_gene CR44279 16-Dec-15 2015_12 FBgn0027868 Nup107 Nucleoporin 107kD http://flybase.net/reports/FBgn0027868.html protein_coding_gene 0005487=nucleocytoplasmic transporter activity "0006406=mRNA export from nucleus, 0007184=SMAD protein import into nucleus" "0005635=nuclear envelope, 0000776=kinetochore, 0031080=nuclear pore outer ring, 0005643=nuclear pore" "Nup107, Nucleoporin 107, dmNup107, CG6743, Nup170, nup107, Nup 107, BcDNA:LD18761" IPR007252=Nuclear pore protein 84/107 CG6743 16-Dec-15 2015_12 ENSDARG00000016010(nup107) YDL116W(NUP84) ENSXETG00000001443(NUP107) ENSMUSG00000052798(Nup107) ENSG00000111581(NUP107) "lethal,recessive" DRSC01999 I -1.773437527 -0.484563148 1.461795437 -0.705786728 -0.771244062 -0.04787634 FBgn0000296 Cg67C Collagen-like 67C http://flybase.net/reports/FBgn0000296.html gene "DCg20, DCg16, Cg11, DCg22, DCg17, DCg11" 16-Dec-15 2015_12 FBgn0028858 CG10839 http://flybase.net/reports/FBgn0028858.html protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement "0030286=dynein complex, 0005875=microtubule associated complex" BG:DS07486.2 "IPR025875=Leucine rich repeat 4, IPR001611=Leucine-rich repeat" CG10839 16-Dec-15 2015_12 ENSXETG00000000061(TGas099a14.1) viable FBgn0065219 l(2)SH2234 lethal (2) SH2234 http://flybase.net/reports/FBgn0065219.html gene l(2)SH2 2234 16-Dec-15 2015_12 "lethal,recessive" FBgn0015521 RpS21 Ribosomal protein S21 http://flybase.net/reports/FBgn0015521.html "FBgn0010545, FBgn0014276" protein_coding_gene "0043022=ribosome binding, 0003735=structural constituent of ribosome" "0000447=endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0042274=ribosomal small subunit biogenesis, 0006412=translation, 0048542=lymph gland development, 0006414=translational elongation, 0000461=endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0042127=regulation of cell proliferation" "0005737=cytoplasm, 0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "oho23B, Rp S21, M(2)23B, rpS21, CG2986, oho23, overgrown hematopoietic organs-23, RpS21, l(2)168/14, overgrown hematopoietic organs at 23B, Ribosomal protein S21, l(2)03575, l(2)k16814, overgrown hematopoietic organs 23B" "IPR001931=Ribosomal protein S21e, IPR018279=Ribosomal protein S21e, conserved site" CG2986 16-Dec-15 2015_12 ENSDARG00000025850(rps21) "YJL136C(RPS21B),YKR057W(RPS21A)" WBGene00004490(rps-21) ENSXETG00000002012(rps21) "ENSMUSG00000039001(Rps21),ENSMUSG00000052192(Gm5963)" embryonic stage -- adult stage embryonic stage -- adult stage "lethal,recessive,wild-type,developmental rate defective,dominant,hyperplasia,visible,short lived,lethal - all die before end of larval stage,some die during larval stage,Minute" "embryonic/larval lymph gland,imaginal disc,ventral thoracic disc,wing disc,adult head,primary lobe of embryonic/larval lymph gland,embryonic/larval hemocyte,macrochaeta,scutum,embryonic/larval brain" DRSC00833 IEK -0.351015164 -1.704300758 -0.942362025 -3.302513483 -0.003517076 2.205533813 FBgn0032740 CG15172 http://flybase.net/reports/FBgn0032740.html protein_coding_gene CG15172 16-Dec-15 2015_12 FBgn0015615 SMC3 Structural maintenance of chromosomes 3 http://flybase.net/reports/FBgn0015615.html protein_coding_gene "0005524=ATP binding, 0046982=protein heterodimerization activity, 0003682=chromatin binding" "0007476=imaginal disc-derived wing morphogenesis, 0046331=lateral inhibition, 0006281=DNA repair, 0022008=neurogenesis, 0007064=mitotic sister chromatid cohesion, 0001737=establishment of imaginal disc-derived wing hair orientation, 0007062=sister chromatid cohesion" "0008280=cohesin core heterodimer, 0008278=cohesin complex" "DmSMC3/Cap, Cap, cohesin subunit SMC3, CG9802, cap, Chromosome-associated protein, DmSMC3, dCAP, CAP, dSMC3, Smc3, SMC3" "IPR010935=SMCs flexible hinge, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR024704=Structural maintenance of chromosomes protein, IPR029685=Structural maintenance of chromosomes protein 3, IPR003395=RecF/RecN/SMC, N-terminal" CG9802 16-Dec-15 2015_12 ENSDARG00000019000(smc3) YJL074C(SMC3) WBGene00004873(smc-3) ENSXETG00000018689(cspg6) ENSMUSG00000024974(Smc3) ENSG00000108055(SMC3) larval stage&&adult stage "planar polarity defective,somatic clone,visible,cell size defective,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,partially lethal - majority die" "wing hair,wing margin,somatic clone,wing vein,ectopic,wing,ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum" DRSC20227 K 0.863071539 0.302431162 -0.508684499 0.874764233 1.843428084 1.709508332 FBgn0259522 GG01017 http://flybase.net/reports/FBgn0259522.html gene 16-Dec-15 2015_12 visible "tarsal segment,antennal segment,arista" FBgn0243513 cnir cornichon related http://flybase.net/reports/FBgn0243513.html "FBgn0064188, FBgn0031499" protein_coding_gene "0035556=intracellular signal transduction, 0016192=vesicle-mediated transport" 0016020=membrane "Cnir, CG17262, Cni-related" IPR003377=Cornichon CG17262 16-Dec-15 2015_12 ENSDARG00000070789 ENSXETG00000018568(BC063923.1) ENSMUSG00000062169(Cnih4) ENSG00000143771(CNIH4) FBgn0003205 Ras85D Ras oncogene at 85D http://flybase.net/reports/FBgn0003205.html "FBgn0011008, FBgn0011548" protein_coding_gene "0005525=GTP binding, 0019003=GDP binding, 0005515=protein binding, 0003924=GTPase activity" "0008283=cell proliferation, 0035099=hemocyte migration, 0048865=stem cell fate commitment, 0046664=dorsal closure, amnioserosa morphology change, 0008361=regulation of cell size, 0043066=negative regulation of apoptotic process, 0036335=intestinal stem cell homeostasis, 0009267=cellular response to starvation, 0008293=torso signaling pathway, 0007428=primary branching, open tracheal system, 0007264=small GTPase mediated signal transduction, 0060438=trachea development, 0007455=eye-antennal disc morphogenesis, 0007552=metamorphosis, 0007309=oocyte axis specification, 0001709=cell fate determination, 0016049=cell growth, 0042066=perineurial glial growth, 0045500=sevenless signaling pathway, 0007369=gastrulation, 0001558=regulation of cell growth, 0043410=positive regulation of MAPK cascade, 0007507=heart development, 0030307=positive regulation of cell growth, 0010507=negative regulation of autophagy, 0008594=photoreceptor cell morphogenesis, 0040008=regulation of growth, 0007472=wing disc morphogenesis, 0046534=positive regulation of photoreceptor cell differentiation, 0030381=chorion-containing eggshell pattern formation, 0038202=TORC1 signaling, 0045610=regulation of hemocyte differentiation, 0008284=positive regulation of cell proliferation, 0007391=dorsal closure, 0048749=compound eye development, 0030707=ovarian follicle cell development, 0007476=imaginal disc-derived wing morphogenesis, 0000082=G1/S transition of mitotic cell cycle, 0006606=protein import into nucleus, 0072089=stem cell proliferation, 0035088=establishment or maintenance of apical/basal cell polarity, 0001708=cell fate specification, 0007298=border follicle cell migration, 0048863=stem cell differentiation, 2001234=negative regulation of apoptotic signaling pathway, 0008586=imaginal disc-derived wing vein morphogenesis, 0007426=tracheal outgrowth, open tracheal system, 0008595=anterior/posterior axis specification, embryo, 0040014=regulation of multicellular organism growth, 0042981=regulation of apoptotic process, 0045793=positive regulation of cell size, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0016242=negative regulation of macroautophagy, 0007422=peripheral nervous system development, 0072002=Malpighian tubule development, 0002168=instar larval development" "0016020=membrane, 0005886=plasma membrane" "CG9375, ras, Ras-1, Ras 85D, DRas85D/Ras, D-Ras, Dm Ras1, DRas, E(faf), RTK, p21[Ras1], Ras GTPase, Ras oncogene at 85B, Ras85DNt, EC3-3, Dras85D, Enhancer of faf, ras85B, DRAS1, l(3)s1747, RAS85D, C-ras1, Dras, Ras85, D-ras1, ras 1, ras85D, fs(3)05703, dras1, dRas, RasI, ras1, Dmras85D, RAS1, dRas85D, P08646, Ras185D, Dras1, dRas1, EK3-4, dRAS1, S35097, Ras1/RAs85D, E(sev)3C, Ras1, Ras, D-ras-1, Ras[V12], Su(tor)3-2, RAS, RasV12, l(3)06677, D-Ras1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR020849=Small GTPase superfamily, Ras type" CG9375 16-Dec-15 2015_12 "ENSDARG00000010844(kras),ENSDARG00000070524(LOC100329754),ENSDARG00000070530(LOC100151000),ENSDARG00000013161(zgc:55558),ENSDARG00000005651(hrasb)" "YOR101W(RAS1),YNL098C(RAS2)" WBGene00002335(let-60) "ENSXETG00000003398(kras),ENSXETG00000014935(nras),ENSXETG00000006040(hras)" "ENSMUSG00000027852(Nras),ENSMUSG00000030265(Kras)" "ENSG00000174775(HRAS),ENSG00000133703(KRAS),ENSG00000213281(NRAS)" " embryonic stage , egg stage | unfertilized egg , embryonic stage | early , adult stage , adult stage && oogenesis stage , larval stage | third instar " " unfertilized egg

, thoracico-abdominal ganglion

, oocyte

, dorsal mesothoracic disc

, eye-antennal disc

, larval brain | restricted

, adult brain | resticted

, genital disc

" "increased cell size,partially lethal - majority die,recessive,female sterile,visible,neuroanatomy defective,viable,partially,lethal,dominant,decreased cell death,wild-type,cell polarity defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,increased cell death,hyperplasia,lethal - all die before end of P-stage,heat sensitive,some die during pharate adult stage,somatic clone,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,cell autonomous,cell non-autonomous,decreased cell size,decreased cell number,germline clone,terminal phenotype,small body,lethal - all die before end of pupal stage,some die during pupal stage,large body,developmental rate defective,temperature conditional,increased cell number,tumorigenic,conditional,cell size defective,learning defective,increased cell growth,short lived,RU486 conditional,cell death defective,some die during P-stage,majority die during P-stage,neoplasia,size defective,female semi-sterile" "eye disc,adult heart,adult heart muscle,myofilament,cardial cell,dorsal appendage,ommatidium,egg chamber,nurse cell,oocyte,ovary,chorion,head,female terminalia,male terminalia,abdominal segment,embryonic/first instar larval cuticle,type I bouton,germarium,spectrosome,egg,tergite,midgut,wing,photoreceptor cell,,eye,midline glial cell,posterior crossvein,wing vein,cone cell,pigment cell,filzkorper,embryonic head,border follicle cell,embryo,eye-antennal disc,secondary pigment cell,tertiary pigment cell,mesothoracic tibial bract,bract,macrochaeta,abdominal ventral monoscolopidial chordotonal organ,abdominal lateral pentascolopidial chordotonal organ,pericardial cell primordium,A1-7 ventral acute muscle 2,imaginal disc,pole cell,salivary gland common duct primordium,gastrula embryo,follicle cell,oocyte associated follicle cell,ommatidial precursor cluster,cyst progenitor cell,adult midgut precursor cell,adult Malpighian tubule,enterocyte,intestinal stem cell,adult head,wing disc,dorsal air sac primordium,ganglionic branch 1 |,germline stem cell,embryonic/larval somatic muscle,dorsal oblique muscle,pericardial cell,dorsal acute muscle,muscle founder cell,mesoderm,mitotic cell cycle,bi-omb-Gal4,hs.PB,interface glial cell,pCC neuron,dMP2 neuron,vMP2 neuron,morphogenetic furrow,anterior crossvein,embryonic/larval ganglionic branch,ë±Tub84B.PP,mesothoracic tergum,repo,peripheral glial cell |,motor neuron |,presumptive embryonic/larval peripheral nervous system,fascicle |,bouton,embryonic segment,tracheal branch primordium,fusion competent cell,embryonic hemocyte,adult gut,enteroblast of posterior adult midgut epithelium,embryonic/larval hemocyte,wing disc posterior compartment,adult midgut precursor cell |,embryonic/larval neuromuscular junction | larval stage,gastric caecum,embryonic/larval oenocyte,wing disc |,embryonic epidermis,GMR.PF,optic cartridge |,lamina,sensory mother cell,-C253,ë±Tub84B.PL,chaeta,coxa,sensillum trichodeum,arista,third segment of antenna,capitellum,haltere pedicel,gonopod thorn bristle,embryonic/larval tracheal system,embryonic/larval trachea,midgut constriction,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,prothoracic gland,denticle,twi.2PE,melanotic mass,hemocyte,interommatidial bristle,rhabdomere,embryonic/larval salivary gland,wing margin,ventral nerve cord,embryonic cardioblast,wing hair,amnioserosa,embryo | dorsal closure stage,embryonic leading edge cell,embryonic/larval brain |,embryonic/larval brain,glial cell,adult brain,optic lobe,embryonic/larval peripheral nervous system |,embryonic/larval midgut,adult midgut precursor cell | prepupal stage P1" DRSC16814 IEK -2.053766822 -5.933335433 -2.961312249 -5.70836373 -3.474241308 -4.513458333 FBgn0263386 CG43438 http://flybase.net/reports/FBgn0263386.html protein_coding_gene lincRNA.111 CG43438 16-Dec-15 2015_12 FBgn0015896 anon-95EFb anon-95EFb http://flybase.net/reports/FBgn0015896.html gene unnamed 16-Dec-15 2015_12 FBgn0084005 CG41439 http://flybase.net/reports/FBgn0084005.html FBan0041439 protein_coding_gene 16-Dec-15 2015_12 FBgn0261285 Ppcs Phosphopantothenoylcysteine synthetase http://flybase.net/reports/FBgn0261285.html "FBgn0086753, FBgn0027595, FBgn0062039" protein_coding_gene 0004632=phosphopantothenate--cysteine ligase activity "0055091=phospholipid homeostasis, 0030708=germarium-derived female germ-line cyst encapsulation, 0046843=dorsal appendage formation, 0070328=triglyceride homeostasis, 0022416=chaeta development, 0030036=actin cytoskeleton organization, 0015937=coenzyme A biosynthetic process, 0007476=imaginal disc-derived wing morphogenesis, 0007297=ovarian follicle cell migration, 0030713=ovarian follicle cell stalk formation, 0007303=cytoplasmic transport, nurse cell to oocyte" "phosphopantothenoylcysteine synthetase, 4'-phosphopantothenoylcysteine synthetase, GH03502, CG5629, dPPCS, anon-WO0118547.401, BcDNA:GH03502, PPCS" "IPR007085=DNA/pantothenate metabolism flavoprotein, C-terminal" CG5629 16-Dec-15 2015_12 ENSDARG00000061889(zgc:136566) YIL083C(CAB2) WBGene00022171(Y71H2AM.6) ENSXETG00000013461(PPCS) ENSMUSG00000028636(Ppcs) ENSG00000127125(PPCS) FBgn0082923 snoRNA:Or-aca3 snoRNA:Or-aca3 http://flybase.net/reports/FBgn0082923.html snoRNA_gene "chr3R:23749517..23749792, Or-aca3, DmOr_aca3 snoRNA, Or_aca3 snoRNA, DmOr_aca3, CR34617" CR34617 16-Dec-15 2015_12 FBgn0012058 Cdc27 Cell division cycle 27 ortholog http://flybase.net/reports/FBgn0012058.html FBgn0024570 protein_coding_gene 0090302=APC-Cdc20 complex activity "0007067=mitotic nuclear division, 0000278=mitotic cell cycle, 0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation" "0071011=precatalytic spliceosome, 0005634=nucleus, 0005680=anaphase-promoting complex, 0000793=condensed chromosome" "Dmcdc27, makos, l(3)L7123, Makos, mks, CG8610, Cdc27, CDC27, Apc3, cdc27, CDC27Dm, APC3" "IPR013026=Tetratricopeptide repeat-containing domain, IPR013105=Tetratricopeptide repeat 2, IPR001440=Tetratricopeptide repeat 1, IPR019734=Tetratricopeptide repeat" CG8610 16-Dec-15 2015_12 ENSDARG00000056258(cdc27) YBL084C(CDC27) WBGene00003132(mat-1) ENSXETG00000003238(CDC27) ENSMUSG00000020687(Cdc27) ENSG00000004897(CDC27) "visible,lethal,recessive,partially lethal - majority die,female limited,female sterile,partially,sterile,short lived,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,decreased cell number,somatic clone,increased cell death,neuroanatomy defective,some die during pupal stage" "wing,spindle & neuroblast,aster & neuroblast,chromosome & neuroblast,chromatin & neuroblast,mitotic metaphase & neuroblast,chromosome | supernumerary,eye,chaeta,mitotic cell cycle,mitosis & nuclear chromosome,spindle & neuroblast & larva,chromosome,chromatin,mitotic metaphase,condensed chromosome & neuroblast & larva,embryonic/larval brain,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC11112 IEK 3.114990628 -4.071975121 6.123000568 -6.573465093 -1.602426924 -2.155705423 FBgn0041229 Gr93a Gustatory receptor 93a http://flybase.net/reports/FBgn0041229.html FBgn0038905 protein_coding_gene 0008527=taste receptor activity "0050909=sensory perception of taste, 0031000=response to caffeine" 0016021=integral component of membrane "GR93, Gustatory receptor 93F.1, 93F.1, CG13417, Gr93F1, GR93F.1, GR93a" IPR013604=7TM chemoreceptor CG13417 16-Dec-15 2015_12 "chemosensitive behavior defective,viable,fertile" FBgn0038084 beat-Vc beat-Vc http://flybase.net/reports/FBgn0038084.html protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "beat Vc, CG14390, Beat-Vc" "IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG14390 16-Dec-15 2015_12 viable FBgn0034366 Atg7 Autophagy-related 7 http://flybase.net/reports/FBgn0034366.html protein_coding_gene "0019778=Atg12 activating enzyme activity, 0019779=Atg8 activating enzyme activity, 0004839=ubiquitin activating enzyme activity" "0016239=positive regulation of macroautophagy, 0032446=protein modification by small protein conjugation, 0010506=regulation of autophagy, 0006914=autophagy, 0050688=regulation of defense response to virus, 0016236=macroautophagy, 0009267=cellular response to starvation, 0008340=determination of adult lifespan, 0006497=protein lipidation, 0048477=oogenesis, 0006501=C-terminal protein lipidation, 0035096=larval midgut cell programmed cell death" 0000407=pre-autophagosomal structure "Autophagy-specific gene 7, autophagy-related protein 7, CG5489, atg-7, autophagy-related gene 7, atg7, ATG7" "IPR000594=THIF-type NAD/FAD binding fold, IPR006285=Ubiquitin-like modifier-activating enzyme Atg7, IPR016040=NAD(P)-binding domain" CG5489 16-Dec-15 2015_12 YHR171W(ATG7) WBGene00010882(atg-7) "ENSMUSG00000030314(Atg7),ENSMUSG00000079831" ENSG00000197548(ATG7) pupal stage salivary gland

"viable,immune response defective,RU486 conditional,memory defective,progressive,decreased cell death,short lived,chemical sensitive,stress response defective,nutrition conditional,somatic clone" "major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16,intestinal stem cell,chemical conditional,autophagic vacuole & larval midgut,embryonic/larval midgut,adult brain,major mitochondrial derivative,embryonic/larval fat body,germarium region 2,nutrition conditional,female germline cyst,egg chamber,egg,somatic clone,germarium,rhabdomere" DRSC05741 IE -1.93654014 -1.692957226 -1.787479904 -0.913538235 -0.494455303 0.165497783 FBgn0003104 PL(3)sp-T2 Polygenic locus sternopleural T2 http://flybase.net/reports/FBgn0003104.html gene "PL(3)sp[T2], 3b" 16-Dec-15 2015_12 FBgn0032857 CG10947 http://flybase.net/reports/FBgn0032857.html protein_coding_gene 38C.42 "IPR019410=Lysine methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG10947 16-Dec-15 2015_12 ENSMUSG00000071037(1700106N22Rik) ENSG00000143919(CAMKMT) viable FBgn0266569 CG42259 http://flybase.net/reports/FBgn0266569.html "FBgn0259144, FBgn0014902" protein_coding_gene "C, anon-1Ea, Transcription unit C" "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG42259 16-Dec-15 2015_12 "WBGene00016097(C25E10.8),WBGene00023417(swm-1),WBGene00016096(C25E10.7),WBGene00015076(B0238.12)" FBgn0032993 CG18117 http://flybase.net/reports/FBgn0032993.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262574 CG43114 http://flybase.net/reports/FBgn0262574.html protein_coding_gene 0006952=defense response MIP09856 "IPR003614=Knottin, scorpion toxin-like" CG43114 16-Dec-15 2015_12 FBgn0266117 CR44843 http://flybase.net/reports/FBgn0266117.html non_protein_coding_gene CR44843 16-Dec-15 2015_12 FBgn0065714 l(2)SH0580 lethal (2) SH0580 http://flybase.net/reports/FBgn0065714.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067305 D11 D11 http://flybase.net/reports/FBgn0067305.html gene 16-Dec-15 2015_12 "lethal,viable" FBgn0051316 CG31316 http://flybase.net/reports/FBgn0051316.html FBgn0064824 protein_coding_gene BcDNA:RH30043 16-Dec-15 2015_12 FBgn0051397 CG31397 http://flybase.net/reports/FBgn0051397.html protein_coding_gene 16-Dec-15 2015_12 DRSC12794 E 0.595782569 0.7106473 1.646060369 -0.994312779 -0.403439417 -0.497844953 FBgn0002155 l(2)mr lethal (2) with morula http://flybase.net/reports/FBgn0002155.html gene l(2)mr[2] 16-Dec-15 2015_12 lethal FBgn0265679 CR44486 http://flybase.net/reports/FBgn0265679.html non_protein_coding_gene lincRNA.184 CR44486 16-Dec-15 2015_12 FBgn0060364 l(3)S138415a lethal (3) S138415a http://flybase.net/reports/FBgn0060364.html gene 1384/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0004767 l(3)89Ef lethal (3) 89Ef http://flybase.net/reports/FBgn0004767.html gene 16-Dec-15 2015_12 lethal FBgn0003578 Su(sc) Suppressor of scute http://flybase.net/reports/FBgn0003578.html gene "sc-Inh-3, scute Inhibitor on chromosome 3, Ext-sct-3" 16-Dec-15 2015_12 macrochaeta FBgn0051408 CG31408 http://flybase.net/reports/FBgn0051408.html protein_coding_gene 16-Dec-15 2015_12 FBgn0023412 Ars-region21 Autonomous replicating sequence region 21 http://flybase.net/reports/FBgn0023412.html region "Ars21, dARS21" 16-Dec-15 2015_12 FBgn0033250 CG14762 http://flybase.net/reports/FBgn0033250.html protein_coding_gene 0048812=neuron projection morphogenesis "CT34565, gp150-like" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG14762 16-Dec-15 2015_12 "WBGene00006370(sym-5),WBGene00006366(sym-1),WBGene00010621(K07A12.2)" viable FBgn0265301 CR44274 http://flybase.net/reports/FBgn0265301.html non_protein_coding_gene CR44274 16-Dec-15 2015_12 FBgn0267914 CR46195 http://flybase.net/reports/FBgn0267914.html non_protein_coding_gene CR46195 16-Dec-15 2015_12 FBgn0030912 CG6023 http://flybase.net/reports/FBgn0030912.html protein_coding_gene CG6023 16-Dec-15 2015_12 "viable,fertile" FBgn0011986 tRNA:S7:64D transfer RNA:ser7:64D http://flybase.net/reports/FBgn0011986.html "FBgn0011968, FBgn0011979, FBgn0052419, FBgn0060066" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033405=UCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[[7]][Ser], tRNA:S7, tRNA[Ser][[7]], chr3L.trna19-SerAGA, AE002602.trna13-SerAGA, 777-5, tRNA:S:AGA:AE002602, tRNA[[Ser]], tRNA:S7:56D, transfer RNA:ser, tRNA[Ser], tRNA:ser7, transfer RNA:ser7, tRNA:ser7:56D, tRNA:S, CR32419, tRNA:ser" CR32419 16-Dec-15 2015_12 FBgn0030031 CG2156 http://flybase.net/reports/FBgn0030031.html protein_coding_gene 0004889=acetylcholine-activated cation-selective channel activity 0005892=acetylcholine-gated channel complex 16-Dec-15 2015_12 FBgn0060648 l(3)S083606b lethal (3) S083606b http://flybase.net/reports/FBgn0060648.html gene 0836/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0025640 CG13369 http://flybase.net/reports/FBgn0025640.html protein_coding_gene 0004747=ribokinase activity 0006014=D-ribose metabolic process "0005634=nucleus, 0005737=cytoplasm" EG:115C2.1 "IPR002173=Carbohydrate/puine kinase, PfkB, conserved site, IPR029056=Ribokinase-like, IPR011611=Carbohydrate kinase PfkB, IPR002139=Ribokinase" CG13369 16-Dec-15 2015_12 ENSDARG00000019877(rbks) YCR036W(RBK1) WBGene00008548(F07A11.5) ENSXETG00000010187(RBKS) ENSMUSG00000029136(Rbks) ENSG00000171174(RBKS) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,supernumerary" FBgn0011745 Arp1 Actin-related protein 1 http://flybase.net/reports/FBgn0011745.html FBgn0026240 protein_coding_gene "0003779=actin binding, 0005200=structural constituent of cytoskeleton" "0007018=microtubule-based movement, 0007010=cytoskeleton organization, 0008090=retrograde axon cargo transport, 0007067=mitotic nuclear division, 0019896=axon transport of mitochondrion, 0008089=anterograde axon cargo transport" "0015629=actin cytoskeleton, 0005869=dynactin complex, 0005875=microtubule associated complex, 0005884=actin filament" "actin-related protein 1, Arp, Arp1, Arp87C, Actr87C, Arp-1, grid, Arp87c, gridlock, ARP87C, gdl, arp1, ARP1, Actin-related protein 87C, CG6174" "IPR004001=Actin, conserved site, IPR020902=Actin/actin-like conserved site, IPR004000=Actin family, IPR029909=Actin-related protein 1 family" CG6174 16-Dec-15 2015_12 ENSDARG00000011611(actr1) WBGene00013168(arp-1) ENSXETG00000015217(ACTR1A) "ENSMUSG00000025228(Actr1a),ENSMUSG00000037351(Actr1b)" "ENSG00000138107(ACTR1A),ENSG00000115073(ACTR1B)" "increased cell death,mitotic cell cycle defective,locomotor behavior defective,cell lethalcell lethal,somatic clone" "synapse,embryonic/larval neuroblast,embryonic/larval brain,oocyte,germline clone" FBgn0031270 CG13689 http://flybase.net/reports/FBgn0031270.html protein_coding_gene CG13689 16-Dec-15 2015_12 "viable,fertile" FBgn0250822 CG34222 http://flybase.net/reports/FBgn0250822.html "FBgn0085251, FBgn0046076, FBgn0045330, FBgn0046065" protein_coding_gene "NEST:bs12c06, NEST:bs11e07, NEST:bs08e11" CG34222 16-Dec-15 2015_12 FBgn0063495 GstE5 Glutathione S transferase E5 http://flybase.net/reports/FBgn0063495.html FBgn0034339 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GSTE5, gstE5, DmGSTE5, gste5, CG17527" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG17527 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0052509 CG32509 http://flybase.net/reports/FBgn0052509.html FBgn0046786 protein_coding_gene BcDNA:GH23462 16-Dec-15 2015_12 FBgn0082165 pkdt polka dots http://flybase.net/reports/FBgn0082165.html gene 16-Dec-15 2015_12 "hemocyte,lamellocyte,supernumerary" FBgn0061158 l(1)7Fi lethal (1) 7Fi http://flybase.net/reports/FBgn0061158.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041165 anon-F1 anon-F1 http://flybase.net/reports/FBgn0041165.html gene F1 16-Dec-15 2015_12 FBgn0001300 ke kidney eye http://flybase.net/reports/FBgn0001300.html gene 16-Dec-15 2015_12 "visible,sterile" "eye,wing,antenna,macrochaeta,wing vein" FBgn0002111 l(2)a lethal (2) a http://flybase.net/reports/FBgn0002111.html gene 16-Dec-15 2015_12 "lethal,recessive,body color defective" FBgn0263504 CR43493 http://flybase.net/reports/FBgn0263504.html non_protein_coding_gene CR43493 16-Dec-15 2015_12 FBgn0262594 CheA46a Chemosensory protein A 46a http://flybase.net/reports/FBgn0262594.html "FBgn0067316, FBgn0053800" protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CheA46a, CG33800" CG33800 16-Dec-15 2015_12 FBgn0037125 CG14573 http://flybase.net/reports/FBgn0037125.html protein_coding_gene CG14573 16-Dec-15 2015_12 FBgn0002618 M(3)80 Minute (3) 80 http://flybase.net/reports/FBgn0002618.html gene "Q-III, QIII, M(3)LS4[Q-III], M(3)Q-III, M(3)LS4" 16-Dec-15 2015_12 "Minute,semidominant,heat sensitive,lethal,developmental rate defective,female sterile,recessive,male sterile,maternal effect,dominant" "eye,heat sensitive,macrochaeta,ocellus,antenna,arista,adult head,adult thorax,scutellum,adult mesothoracic segment,wing vein L2,wing vein L4,leg,prothoracic leg,tarsal segment,femur,sex comb,male genitalia,adult abdomen" FBgn0014368 nol no optic lobe http://flybase.net/reports/FBgn0014368.html FBgn0052077 protein_coding_gene 0007405=neuroblast proliferation 0005576=extracellular region CG32077 CG32077 16-Dec-15 2015_12 viable FBgn0263655 CG43646 http://flybase.net/reports/FBgn0263655.html protein_coding_gene "mlncRNA42E5-2, lincRNA.258" CG43646 16-Dec-15 2015_12 FBgn0063646 CE2-3 "Calcineurin enhancer, chromosome 2, group 3" http://flybase.net/reports/FBgn0063646.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265445 CR44345 http://flybase.net/reports/FBgn0265445.html non_protein_coding_gene CR44345 16-Dec-15 2015_12 FBgn0004552 Akh Adipokinetic hormone http://flybase.net/reports/FBgn0004552.html "FBgn0004086, FBgn0004508" protein_coding_gene "0005184=neuropeptide hormone activity, 0097005=adipokinetic hormone receptor binding" 0007218=neuropeptide signaling pathway 0005615=extracellular space "Drm-AKH, Adipokinetic hormone-like, adipo- kinetic hormone, Hypertrehaloseaemic-hormone, akh, Hrth, adipokinetic hormone, AKH1, AKH, dAkh, CG1171, Adipokinetic Hormone" "IPR010475=Adipokinetic hormone/red pigment-concentrating hormone, IPR002047=Adipokinetic hormone, conserved site" CG1171 16-Dec-15 2015_12 adult stage adult thorax

viable lipid particlefat FBgn0264679 CR43964 http://flybase.net/reports/FBgn0264679.html non_protein_coding_gene CR43964 16-Dec-15 2015_12 FBgn0020503 CLIP-190 Cytoplasmic linker protein 190 http://flybase.net/reports/FBgn0020503.html protein_coding_gene "0008017=microtubule binding, 0070854=myosin VI heavy chain binding, 0003779=actin binding, 0051010=microtubule plus-end binding, 0005515=protein binding" "0007017=microtubule-based process, 0007349=cellularization" "0045169=fusome, 0030424=axon, 0005794=Golgi apparatus, 0005938=cell cortex, 0005876=spindle microtubule, 0000776=kinetochore, 0044295=axonal growth cone, 0005875=microtubule associated complex, 0035371=microtubule plus-end" "cytoplasmic linker protein 190, D-CLIP-190, CLIP-190, Clip-190, Clip- 190, Clip190, CG5020, D-CLIP-90, CLIP190, D-CLIP-195, D-Clip-190, cytoplasmic linker protein-190, D-CLIP-19" IPR000938=CAP Gly-rich domain CG5020 16-Dec-15 2015_12 ENSDARG00000059596(LOC556406) ENSXETG00000003780(CLIP1) "ENSMUSG00000049550(Clip1),ENSMUSG00000063146(Clip2)" "ENSG00000130779(CLIP1),ENSG00000106665(CLIP2)" viable FBgn0036062 CG6685 http://flybase.net/reports/FBgn0036062.html protein_coding_gene CG6685 16-Dec-15 2015_12 FBgn0019700 l(2)94 lethal (2) 94 http://flybase.net/reports/FBgn0019700.html gene 16-Dec-15 2015_12 lethal FBgn0000741 fs(1)A125 female sterile (1) A125 http://flybase.net/reports/FBgn0000741.html gene 0048477=oogenesis fs(1)125 16-Dec-15 2015_12 "female semi-sterile,recessive,heat sensitive" dorsal appendage FBgn0036225 CG5883 http://flybase.net/reports/FBgn0036225.html protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG5883 16-Dec-15 2015_12 viable FBgn0040846 CG17496 http://flybase.net/reports/FBgn0040846.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266882 CR45343 http://flybase.net/reports/FBgn0266882.html non_protein_coding_gene CR45343 16-Dec-15 2015_12 FBgn0262545 CG43099 http://flybase.net/reports/FBgn0262545.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030316 CG11695 http://flybase.net/reports/FBgn0030316.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus c "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG11695 16-Dec-15 2015_12 "viable,fertile" FBgn0262955 RpII140 RNA polymerase II 140kD subunit http://flybase.net/reports/FBgn0262955.html "FBgn0003276, FBgn0083157" protein_coding_gene "0032549=ribonucleoside binding, 0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity" 0006366=transcription from RNA polymerase II promoter "0005665=DNA-directed RNA polymerase II, core complex" "RNA polymerase II 140 kD subunit, CG3180, RNA polymeraseII-140 kd subunit, l(3)RplII140, RNApolII, 150kDa polypeptide, PolII, RP140, RNAP II, RNA Pol IIc, RNA polymerase IIc, RNA pol II second largest subunit, subunit IIc of RNA Pol II, RPII140, rpII140/wimp, polII, RpII140[wimp], unnamed, RNA polII, RNA polymerase II second largest subunit, PolIIc, DmRP140, II, RNA pol II, RNA Pol II 140, wimp, pol II, Pol IIc, RNA Pol II, Rpll140, RPB2_DROME, H5, RNAP, Rpb2, RNA polymerase subunit IIc, Pol II, RNA Pol II second largest subunit, RNA polymerase II" "IPR007646=RNA polymerase Rpb2, domain 4, IPR007647=RNA polymerase Rpb2, domain 5, IPR007645=RNA polymerase Rpb2, domain 3, IPR007644=RNA polymerase, beta subunit, protrusion, IPR015712=DNA-directed RNA polymerase, subunit 2, IPR007121=RNA polymerase, beta subunit, conserved site, IPR007642=RNA polymerase Rpb2, domain 2, IPR014724=RNA polymerase Rpb2, OB-fold, IPR007641=RNA polymerase Rpb2, domain 7, IPR007120=DNA-directed RNA polymerase, subunit 2, domain 6" CG3180 16-Dec-15 2015_12 YOR151C(RPB2) WBGene00016140(rpb-2) ENSXETG00000005329(POLR2B) ENSMUSG00000029250(Polr2b) ENSG00000047315(POLR2B) DRSC16831 IEK 0.285200585 3.984708868 -0.012586792 -2.186545947 2.058492903 1.987690337 FBgn0264856 AP-2ë±::numb http://flybase.net/reports/FBgn0264856.html engineered_fusion_gene alpha-Adaptin::numb 16-Dec-15 2015_12 neuroanatomy defective secondary neuroblast FBgn0264429 CR43847 http://flybase.net/reports/FBgn0264429.html non_protein_coding_gene lincRNA.851 CR43847 16-Dec-15 2015_12 FBgn0024635 l(2)k13825 lethal (2) k13825 http://flybase.net/reports/FBgn0024635.html gene 138/25 16-Dec-15 2015_12 "lethal,recessive" FBgn0036395 CG17361 http://flybase.net/reports/FBgn0036395.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG17361 16-Dec-15 2015_12 "viable,fertile" FBgn0035584 CG17030 http://flybase.net/reports/FBgn0035584.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0000209=protein polyubiquitination "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG17030 16-Dec-15 2015_12 viable FBgn0027287 Gmap Golgi microtubule-associated protein http://flybase.net/reports/FBgn0027287.html "FBgn0030649, FBgn0030650, FBgn0052587" protein_coding_gene 0017137=Rab GTPase binding "0000042=protein targeting to Golgi, 0016192=vesicle-mediated transport, 0007030=Golgi organization" "0000137=Golgi cis cisterna, 0005795=Golgi stack, 0000139=Golgi membrane" "l(1)G0168, GMAP210, lethal (1) G0168, CG6350, CG32587, dGMAP, GMAP-210, CG7821, GMAP, CG33206" IPR000237=GRIP CG33206 16-Dec-15 2015_12 ENSXETG00000015833() ENSMUSG00000021188(Trip11) ENSG00000100815(TRIP11) "visible,viable,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "wing,costal cell,Golgi stackunspecified" FBgn0036592 CG13049 http://flybase.net/reports/FBgn0036592.html FBgn0062450 protein_coding_gene 0007030=Golgi organization 0005794=Golgi apparatus BcDNA:RE26528 CG13049 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0039228 CG6980 http://flybase.net/reports/FBgn0039228.html FBgn0044706 protein_coding_gene anon-WO0140519.171 "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR023114=Elongated TPR repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG6980 16-Dec-15 2015_12 WBGene00016375(C33H5.8) viable FBgn0034245 UQCR-6.4 Ubiquinol-cytochrome c reductase 6.4 kDa subunit http://flybase.net/reports/FBgn0034245.html protein_coding_gene "0009055=electron carrier activity, 0008121=ubiquinol-cytochrome-c reductase activity" "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" 0005750=mitochondrial respiratory chain complex III "CG14482, UCRY, Ubiquinol-cytochrome c reductase 6.4 kDa protein, Ubiquinol-cytochrome c oxidoreductase 6.4 kDa, Ubiquinol-cytochrome C reductase complex 6.4 kDa protein" "IPR015089=Cytochrome b-c1 complex subunit 10, IPR029027=Single alpha-helix domain" CG14482 16-Dec-15 2015_12 viable FBgn0035622 TM9SF3 Transmembrane 9 superfamily protein member 3 http://flybase.net/reports/FBgn0035622.html protein_coding_gene "0016021=integral component of membrane, 0005768=endosome" "TM9SF3, CG10590" IPR004240=Nonaspanin (TM9SF) CG10590 16-Dec-15 2015_12 ENSDARG00000028748(tm9sf3) WBGene00021506(Y41D4A.4) ENSXETG00000010642(TM9SF3) ENSMUSG00000025016(Tm9sf3) ENSG00000077147(TM9SF3) viable FBgn0001936 l(2)25Fb lethal (2) 25Fb http://flybase.net/reports/FBgn0001936.html gene l(2)gdh-17 16-Dec-15 2015_12 "lethal,recessive" FBgn0035154 CG3344 http://flybase.net/reports/FBgn0035154.html protein_coding_gene 0004185=serine-type carboxypeptidase activity 0006508=proteolysis "IPR029058=Alpha/Beta hydrolase fold, IPR001563=Peptidase S10, serine carboxypeptidase" CG3344 16-Dec-15 2015_12 ENSDARG00000040072(scpep1) YGL203C(KEX1) WBGene00012530(Y32F6A.5) ENSXETG00000020061(SCPEP1) ENSMUSG00000000278(Scpep1) ENSG00000121064(SCPEP1) viable DRSC08564 K 0.961224219 0.281742135 0.7139568 0.730464274 -1.600264103 -0.530084701 FBgn0283429 CR46272 http://flybase.net/reports/FBgn0283429.html pseudogene_attribute CR46272 16-Dec-15 2015_12 FBgn0005136 l(1)Y110 lethal (1) Y110 http://flybase.net/reports/FBgn0005136.html gene 16-Dec-15 2015_12 lethal ommatidium FBgn0036242 CG6793 http://flybase.net/reports/FBgn0036242.html protein_coding_gene 0005875=microtubule associated complex CG6793 16-Dec-15 2015_12 FBgn0039766 CG15536 http://flybase.net/reports/FBgn0039766.html protein_coding_gene CG15536 16-Dec-15 2015_12 FBgn0263449 CR43472 http://flybase.net/reports/FBgn0263449.html non_protein_coding_gene CR43472 16-Dec-15 2015_12 FBgn0035981 CG4452 http://flybase.net/reports/FBgn0035981.html FBgn0046475 protein_coding_gene "cg4452, anon-WO0172774.118" CG4452 16-Dec-15 2015_12 ENSDARG00000012432(fam76b) WBGene00019399(K04F10.7) ENSXETG00000007080(TGas096i10.1) "ENSMUSG00000028878(Fam76a),ENSMUSG00000037808(Fam76b)" "ENSG00000077458(FAM76B),ENSG00000009780(FAM76A)" "viable,fertile" DRSC10422 E 0.675023533 0.296345421 1.988799592 0.791214071 0.298275154 0.058985484 FBgn0002883 mus108 mutagen-sensitive 108 http://flybase.net/reports/FBgn0002883.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive,radiation sensitive" FBgn0051183 CG31183 http://flybase.net/reports/FBgn0051183.html "FBgn0038378, FBgn0038379" protein_coding_gene "0004672=protein kinase activity, 0016941=natriuretic peptide receptor activity, 0004872=receptor activity, 0005524=ATP binding, 0004383=guanylate cyclase activity" "0009190=cyclic nucleotide biosynthetic process, 0006468=protein phosphorylation, 0019934=cGMP-mediated signaling" 0005887=integral component of plasma membrane "CG4224, CG11846, FBgn0038379, GYC" "IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001170=Natriuretic peptide receptor, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site" CG31183 16-Dec-15 2015_12 "ENSDARG00000031751(si:dkey-27c15.1),ENSDARG00000018750,ENSDARG00000011390" WBGene00020131(gcy-28) "ENSXETG00000014291(NPR1),ENSXETG00000009854(NPR2)" "ENSMUSG00000027931(Npr1),ENSMUSG00000028469(Npr2)" "ENSG00000169418(NPR1),ENSG00000159899(NPR2)" viable DRSC15554 K 0.80358871 0.401442482 0.142888164 0.679235797 0.915804915 4.396174871 FBgn0085795 CR41535 http://flybase.net/reports/FBgn0085795.html FBan0041535 rRNA_gene CR41535 16-Dec-15 2015_12 FBgn0016853 l(1)N34 lethal (1) N34 http://flybase.net/reports/FBgn0016853.html gene N34 16-Dec-15 2015_12 "lethal,recessive" FBgn0037974 CG12224 http://flybase.net/reports/FBgn0037974.html protein_coding_gene 0016491=oxidoreductase activity "IPR023210=NADP-dependent oxidoreductase domain, IPR001395=Aldo/keto reductase" CG12224 16-Dec-15 2015_12 YMR041C(ARA2) WBGene00003176(mec-14) ENSXETG00000016911() viable DRSC14480 K 0.289866199 0.397684889 0.680578299 0.387322333 1.860860217 0.235889008 FBgn0015965 l(2)46DEc lethal (2) 46DEc http://flybase.net/reports/FBgn0015965.html gene group 7 16-Dec-15 2015_12 "lethal,recessive" FBgn0027101 Dyrk3 Dual-specificity tyrosine phosphorylation-regulated kinase 3 http://flybase.net/reports/FBgn0027101.html "FBgn0062988, FBgn0069975" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation "DDYRK3, DYRK3, FBtr0100406, CG40478, Dm3, BcDNA:RE60792, Dyrk3, DmDyrk3, unknown-telomeric-protein-gene" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG40478 16-Dec-15 2015_12 YJL141C(YAK1) WBGene00016464(C36B7.1) viable FBgn0031895 CG4497 http://flybase.net/reports/FBgn0031895.html protein_coding_gene IPR026716=FAM122 CG4497 16-Dec-15 2015_12 "ENSG00000156504(FAM122B),ENSG00000187866(FAM122A)" "viable,fertile" FBgn0062635 ER2-8A ER2-8A http://flybase.net/reports/FBgn0062635.html gene 16-Dec-15 2015_12 FBgn0032900 CG14401 http://flybase.net/reports/FBgn0032900.html protein_coding_gene CG14401 16-Dec-15 2015_12 viable DRSC21710 I 3.551163599 1.243030575 -0.319566656 0.272119786 0.996092046 -0.172098153 FBgn0063368 Gpb5 Glycoprotein hormone beta 5 ortholog (H. sapiens) http://flybase.net/reports/FBgn0063368.html "FBgn0058041, FBan0040041" protein_coding_gene "0001664=G-protein coupled receptor binding, 0046982=protein heterodimerization activity, 0005179=hormone activity" 0009755=hormone-mediated signaling pathway "0005615=extracellular space, 0005576=extracellular region" "Dmbeta, Glycoprotein hormone beta 5, GPB5, beta-glycoprotein-hormone-related, CG40041, beta-glycoprotein-hormone-related-polypeptide, gpb5" "IPR006208=Glycoprotein hormone subunit beta, cystine knot, IPR029034=Cystine-knot cytokine, IPR001545=Gonadotropin, beta subunit" CG40041 16-Dec-15 2015_12 "ENSDARG00000027472,ENSDARG00000035709(lhb),ENSDARG00000033726(tshb)" ENSMUSG00000048982(Gphb5) ENSG00000179600 partially lethal - majority die FBgn0263344 CR43425 http://flybase.net/reports/FBgn0263344.html non_protein_coding_gene CR43425 16-Dec-15 2015_12 FBgn0032235 CG5096 http://flybase.net/reports/FBgn0032235.html protein_coding_gene CT16355 "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype, IPR026906=Leucine rich repeat 5" CG5096 16-Dec-15 2015_12 viable DRSC02813 K 0.274781647 0.455684965 0.197854546 -0.212803788 2.158008308 -0.485972745 FBgn0052748 tRNA:CR32748 transfer RNA:CR32748 http://flybase.net/reports/FBgn0052748.html FBgn0060236 tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR32748, tRNA:F:GAA:AE002566-a, AE002566.trna4-PheGAA, chrX.trna4-PheGAA" CR32748 16-Dec-15 2015_12 FBgn0014122 anon-96Ca anon-96Ca http://flybase.net/reports/FBgn0014122.html gene 16-Dec-15 2015_12 FBgn0033127 Tsp42Ef Tetraspanin 42Ef http://flybase.net/reports/FBgn0033127.html protein_coding_gene 0008340=determination of adult lifespan 0016021=integral component of membrane "tetraspanin 42E, CG12845, Dm.Tsp42Ef, Tetraspanin 42eF, tetraspanin42Ef" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG12845 16-Dec-15 2015_12 "viable,long lived,RU486 conditional,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0002544 lem lemon http://flybase.net/reports/FBgn0002544.html gene 16-Dec-15 2015_12 "visible,recessive,semi-sterile,body color defective" FBgn0010877 l(3)05822 lethal (3) 05822 http://flybase.net/reports/FBgn0010877.html FBgn0038599 protein_coding_gene "5822, l(3)5822, L(3)05822, CG7129, clot 3142, LD12970" IPR001452=SH3 domain CG7129 16-Dec-15 2015_12 WBGene00015128(B0303.7) ENSXETG00000009395() "lethal,recessive" FBgn0034856 yellow-d2 yellow-d2 http://flybase.net/reports/FBgn0034856.html protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "yel-d2, CG9891, d2, CT27880" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG9891 16-Dec-15 2015_12 viable DRSC04591 IK 2.785719553 -0.005359327 0.412312804 -0.004518426 1.121096033 1.553029613 FBgn0028006 l(3)S115909 lethal (3) S115909 http://flybase.net/reports/FBgn0028006.html gene 1159/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0003010 orn ornamented http://flybase.net/reports/FBgn0003010.html gene 16-Dec-15 2015_12 FBgn0019676 mor(1)3 mortality gene (1)3 http://flybase.net/reports/FBgn0019676.html gene 16-Dec-15 2015_12 short lived FBgn0065990 doc docked http://flybase.net/reports/FBgn0065990.html gene 0007476=imaginal disc-derived wing morphogenesis 16-Dec-15 2015_12 "viable,lethal,recessive,visible" wing FBgn0265486 BG00737 http://flybase.net/reports/FBgn0265486.html gene 16-Dec-15 2015_12 FBgn0085284 Blos3 "Biogenesis of lysosome-related organelles complex 1, subunit 3" http://flybase.net/reports/FBgn0085284.html protein_coding_gene 0031083=BLOC-1 complex "BLOS3, BLOC-1 subunit 3, CG34255, blos3, NP_001097640, Dm Blos3" "IPR017245=BLOC-1 complex, subunit 3" CG34255 16-Dec-15 2015_12 FBgn0262286 mir-1001 mir-1001 stem loop http://flybase.net/reports/FBgn0262286.html miRNA_gene 0046716=muscle cell cellular homeostasis "CR42993, dme-mir-1001, miR-1001" CR42993 16-Dec-15 2015_12 "lethal,male limited" FBgn0038533 CG7523 http://flybase.net/reports/FBgn0038533.html protein_coding_gene IPR029399=TMEM192 family CG7523 16-Dec-15 2015_12 ENSDARG00000037484(LOC100329257) ENSXETG00000017061(BC090374.1) ENSMUSG00000025521(Tmem192) ENSG00000170088(TMEM192) FBgn0036328 CG10749 http://flybase.net/reports/FBgn0036328.html protein_coding_gene 0030060=L-malate dehydrogenase activity "0005975=carbohydrate metabolic process, 0006099=tricarboxylic acid cycle, 0006108=malate metabolic process" "0005739=mitochondrion, 0005759=mitochondrial matrix" "IPR010097=Malate dehydrogenase, type 1, IPR016040=NAD(P)-binding domain, IPR001252=Malate dehydrogenase, active site, IPR001557=L-lactate/malate dehydrogenase, IPR022383=Lactate/malate dehydrogenase, C-terminal, IPR001236=Lactate/malate dehydrogenase, N-terminal, IPR015955=Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal" CG10749 16-Dec-15 2015_12 ENSDARG00000043371 YKL085W(MDH1) viable FBgn0037811 CG12592 http://flybase.net/reports/FBgn0037811.html protein_coding_gene CG12592-PA CG12592 16-Dec-15 2015_12 FBgn0038938 CG7084 http://flybase.net/reports/FBgn0038938.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity "0055085=transmembrane transport, 0022008=neurogenesis" 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG7084 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" FBgn0262249 mir-958 mir-958 stem loop http://flybase.net/reports/FBgn0262249.html miRNA_gene "dme-miR-958, miR-958, CR42956" CR42956 16-Dec-15 2015_12 "visible,viable,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during P-stage" "wing,wing vein,ectopic" FBgn0042131 CG18808 http://flybase.net/reports/FBgn0042131.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR003767=Malate/L-lactate dehydrogenase CG18808 16-Dec-15 2015_12 ENSXETG00000012341() viable FBgn0034228 CG14479 http://flybase.net/reports/FBgn0034228.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0032945 CG8665 http://flybase.net/reports/FBgn0032945.html protein_coding_gene "0008168=methyltransferase activity, 0016155=formyltetrahydrofolate dehydrogenase activity, 0016742=hydroxymethyl-, formyl- and related transferase activity, 0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" "0006730=one-carbon metabolic process, 0055114=oxidation-reduction process, 0009058=biosynthetic process, 0009258=10-formyltetrahydrofolate catabolic process" 0005737=cytoplasm "IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR016163=Aldehyde dehydrogenase, C-terminal, IPR001555=Phosphoribosylglycinamide formyltransferase, active site, IPR015590=Aldehyde dehydrogenase domain, IPR016161=Aldehyde/histidinol dehydrogenase, IPR002376=Formyl transferase, N-terminal, IPR011407=10-formyltetrahydrofolate dehydrogenase, IPR016160=Aldehyde dehydrogenase, cysteine active site, IPR009081=Acyl carrier protein-like, IPR011034=Formyl transferase, C-terminal-like, IPR029510=Aldehyde dehydrogenase, glutamic acid active site, IPR005793=Formyl transferase, C-terminal" CG8665 16-Dec-15 2015_12 ENSDARG00000070230(LOC100333269) WBGene00000109(alh-3) "ENSXETG00000001886(ALDH1L2),ENSXETG00000011551(Q63ZT8_XENTR)" "ENSMUSG00000020256(Aldh1l2),ENSMUSG00000030088(Aldh1l1)" "ENSG00000144908(ALDH1L1),ENSG00000136010(ALDH1L2)" viable FBgn0038172 Adgf-D Adenosine deaminase-related growth factor D http://flybase.net/reports/FBgn0038172.html protein_coding_gene "0008083=growth factor activity, 0004000=adenosine deaminase activity" "0043103=hypoxanthine salvage, 0046103=inosine biosynthetic process, 0006154=adenosine catabolic process, 0008283=cell proliferation" "0005615=extracellular space, 0005829=cytosol" "adgfd, CG9621, ADGF-D, ADGFD, AdgfD" "IPR013659=Adenosine/AMP deaminase N-terminal, IPR001365=Adenosine/AMP deaminase domain, IPR006331=Adenosine deaminase-related growth factor" CG9621 16-Dec-15 2015_12 ENSXETG00000000874(CECR1) viable FBgn0266428 CR43463 http://flybase.net/reports/FBgn0266428.html "FBgn0263440, FBgn0066056" non_protein_coding_gene anon-35Aa CR43463 16-Dec-15 2015_12 FBgn0015506 l(3)EGX4 lethal (3) EGX4 http://flybase.net/reports/FBgn0015506.html gene "PGX4, EGX4" 16-Dec-15 2015_12 "lethal,recessive" FBgn0023044 l(1)5-39-1 lethal (1) 5-39-1 http://flybase.net/reports/FBgn0023044.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050279 CG30279 http://flybase.net/reports/FBgn0050279.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0265944 CR44731 http://flybase.net/reports/FBgn0265944.html non_protein_coding_gene CR44731 16-Dec-15 2015_12 FBgn0005076 fs(2)OW217 female sterile (2) OW217 http://flybase.net/reports/FBgn0005076.html gene 16-Dec-15 2015_12 FBgn0028632 ksh-15 ksh-15 http://flybase.net/reports/FBgn0028632.html gene 16-Dec-15 2015_12 FBgn0000960 fs(2)E7 female sterile (2) E7 http://flybase.net/reports/FBgn0000960.html gene fs2.7 16-Dec-15 2015_12 "female sterile,recessive" "vitelline membrane,egg" FBgn0243515 nrv2::nrv3 http://flybase.net/reports/FBgn0243515.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0260393 CG17147 http://flybase.net/reports/FBgn0260393.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG17147 16-Dec-15 2015_12 viable FBgn0264479 CR43887 http://flybase.net/reports/FBgn0264479.html non_protein_coding_gene CR43887 16-Dec-15 2015_12 FBgn0263201 scaRNA:MeU1b-A234 small Cajal body-specific RNA : MeU1b-A234 http://flybase.net/reports/FBgn0263201.html "FBgn0261007, FBgn0086721" snoRNA_gene 0015030=Cajal body "scaRNA:46E3, scaDm46E3, snoRNA:46E1, Dm46E3, Dm46E1" CR43567 16-Dec-15 2015_12 FBgn0033584 CG7737 http://flybase.net/reports/FBgn0033584.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process "IPR002937=Amine oxidase, IPR016040=NAD(P)-binding domain" CG7737 16-Dec-15 2015_12 viable FBgn0264999 CR44150 http://flybase.net/reports/FBgn0264999.html non_protein_coding_gene lincRNA.94 CR44150 16-Dec-15 2015_12 FBgn0260481 CG32454 http://flybase.net/reports/FBgn0260481.html FBgn0052454 protein_coding_gene "0004177=aminopeptidase activity, 0030145=manganese ion binding, 0008235=metalloexopeptidase activity" 0006508=proteolysis CG11367 "IPR029149=Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980=Creatinase/Aminopeptidase P, N-terminal, IPR000994=Peptidase M24, structural domain, IPR007865=Aminopeptidase P, N-terminal" CG32454 16-Dec-15 2015_12 viable FBgn0040874 CG15600 http://flybase.net/reports/FBgn0040874.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000205 bos bordosteril http://flybase.net/reports/FBgn0000205.html gene 16-Dec-15 2015_12 "visible,recessive,fertile,male,female sterile,eye color defective" "eye,Malpighian tubule,pigment cell" FBgn0000064 Ald Aldolase http://flybase.net/reports/FBgn0000064.html FBgn0064914 protein_coding_gene 0004332=fructose-bisphosphate aldolase activity "0007498=mesoderm development, 0006096=glycolytic process, 0007095=mitotic G2 DNA damage checkpoint" "0005829=cytosol, 0031430=M band, 0030018=Z disc" "T6, T4, FBA, fructose 1,6 biphosphate-aldolase A, ALD, ald, Aldolase, aldolase, T12, T7, CG6058, BcDNA:LP07735" "IPR029768=Fructose-bisphosphate aldolase class-I active site, IPR029769=Fructose-bisphosphate aldolase class-I, eukaryotic-type, IPR013785=Aldolase-type TIM barrel, IPR000741=Fructose-bisphosphate aldolase, class-I" CG6058 16-Dec-15 2015_12 "ENSDARG00000011665(aldoaa),ENSDARG00000034470(aldoab),ENSDARG00000019702(aldocb),ENSDARG00000053684(aldob),ENSDARG00000057661(aldoca)" "WBGene00011474(aldo-1),WBGene00017166(aldo-2)" "ENSXETG00000027677(aldoc),ENSXETG00000020674(aldoa),ENSXETG00000024058(aldob)" "ENSMUSG00000030695(Aldoa),ENSMUSG00000059343,ENSMUSG00000063129,ENSMUSG00000017390(Aldoc),ENSMUSG00000028307(Aldob)" "ENSG00000149925(ALDOA),ENSG00000109107(ALDOC),ENSG00000136872(ALDOB)" "paralytic,recessive,heat sensitive,short lived,neuroanatomy defective,progressive,viable,fertile,electrophoretic variant,fast,slow,visible,lethal" "adult brain,progressive,optic lobe,trichogen cell" FBgn0261293 CheB53b Chemosensory protein B 53b http://flybase.net/reports/FBgn0261293.html "FBgn0067309, FBgn0053524, FBgn0053457" protein_coding_gene 0008289=lipid binding "0043695=detection of pheromone, 0007606=sensory perception of chemical stimulus" "0005576=extracellular region, 0005615=extracellular space" "CheB53b, CG33524, CG33457" CG33524 16-Dec-15 2015_12 FBgn0033482 CG1371 http://flybase.net/reports/FBgn0033482.html protein_coding_gene 0030246=carbohydrate binding 0012505=endomembrane system "IPR013783=Immunoglobulin-like fold, IPR014766=Carboxypeptidase, regulatory domain, IPR013784=Carbohydrate-binding-like fold" CG1371 16-Dec-15 2015_12 WBGene00015344(nra-4) ENSXETG00000019683() ENSMUSG00000030835(Nomo1) "ENSG00000185164(NOMO2),ENSG00000103226(NOMO3),ENSG00000103512(NOMO1)" "partially lethal - majority die,some die during pupal stage" FBgn0011071 l(1)Q24 lethal (1) Q24 http://flybase.net/reports/FBgn0011071.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0028224 l(3)S005818 lethal (3) S005818 http://flybase.net/reports/FBgn0028224.html gene "58/18, 0058/18" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267016 CR45460 http://flybase.net/reports/FBgn0267016.html non_protein_coding_gene CR45460 16-Dec-15 2015_12 FBgn0030668 CG8128 http://flybase.net/reports/FBgn0030668.html protein_coding_gene 0016787=hydrolase activity 0051726=regulation of cell cycle "IPR003293=Nudix hydrolase 6-like, IPR000086=NUDIX hydrolase domain, IPR015797=NUDIX hydrolase domain-like, IPR020084=NUDIX hydrolase, conserved site, IPR020476=NUDIX hydrolase" CG8128 16-Dec-15 2015_12 ENSDARG00000019653 ENSXETG00000001585(NUDT6) ENSMUSG00000050174(Nudt6) ENSG00000170917(NUDT6) viable FBgn0003003 opb opaque broad http://flybase.net/reports/FBgn0003003.html gene 16-Dec-15 2015_12 "visible,recessive,female sterile,male fertile,viable,male,poor,eye color defective" "wing,abdomen,genitalia,leg,adult abdomen,pigment cell" FBgn0033629 Tsp47F Tetraspanin 47F http://flybase.net/reports/FBgn0033629.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp47F, CG9033" "IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG9033 16-Dec-15 2015_12 "ENSDARG00000038288(cd151),ENSDARG00000001781(si:dkey-21h14.7),ENSDARG00000068629(cd151l)" ENSMUSG00000025351(Cd63) ENSG00000135404(CD63) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC07325 E -1.304622244 -1.174516611 -0.013770338 -1.697743159 0.01999032 -0.228397189 FBgn0034535 CG11110 http://flybase.net/reports/FBgn0034535.html protein_coding_gene 0008236=serine-type peptidase activity 0006627=protein processing involved in protein targeting to mitochondrion 0005743=mitochondrial inner membrane serine-type peptidase "IPR028360=Peptidase S24/S26, beta-ribbon domain, IPR019759=Peptidase S24/S26A/S26B, IPR000223=Peptidase S26A, signal peptidase I, IPR015927=Peptidase S24/S26A/S26B/S26C" CG11110 16-Dec-15 2015_12 ENSDARG00000004925(immp2l) YMR035W(IMP2) WBGene00021925(immp-2) ENSMUSG00000056899(Immp2l) ENSG00000184903(IMMP2L) viable DRSC27355 EK 1.479846205 1.458789777 2.145063884 0.668947345 1.737248778 0.539701275 FBgn0250851 CG33981 http://flybase.net/reports/FBgn0250851.html "FBgn0053981, FBgn0083929" protein_coding_gene "unnamed, BEST:GH01256, APC13" IPR008401=Apc13p CG33981 16-Dec-15 2015_12 ENSXETG00000025461(anapc13) ENSMUSG00000035048(Anapc13) ENSG00000129055(ANAPC13) FBgn0031381 Npc2a Niemann-Pick type C-2a http://flybase.net/reports/FBgn0031381.html "FBgn0043830, FBgn0063229, FBgn0064798" protein_coding_gene "0042834=peptidoglycan binding, 0070891=lipoteichoic acid binding, 0032934=sterol binding, 0030882=lipid antigen binding, 0001530=lipopolysaccharide binding" "0045456=ecdysteroid biosynthetic process, 0061057=peptidoglycan recognition protein signaling pathway, 0055092=sterol homeostasis, 0008039=synaptic target recognition, 0015918=sterol transport" "0005576=extracellular region, 0005615=extracellular space" "DmML3, npc2a, BcDNA:RH53228, Epididymal secretory protein, dnpc2a, Niemann-Pick Type C-2, BcDNA:GH22047, BEST:GH08376, CG7291, CT22505, NPC2" "IPR003172=MD-2-related lipid-recognition domain, IPR014756=Immunoglobulin E-set" CG7291 16-Dec-15 2015_12 "ENSDARG00000033412(npc2),ENSDARG00000004421(zgc:193725)" WBGene00006452(heh-1) ENSXETG00000013295(npc2) ENSMUSG00000021242(Npc2) ENSG00000119655(NPC2) "viable,fertile,short lived" Malpighian tubule DRSC00698 K 0.270171765 0.323355966 -0.381211452 0.264135258 2.008471713 1.145146139 FBgn0014178 ftz::Dr ftz::Dr http://flybase.net/reports/FBgn0014178.html engineered_fusion_gene ftz::msh 16-Dec-15 2015_12 FBgn0266900 CR45360 http://flybase.net/reports/FBgn0266900.html non_protein_coding_gene CR45360 16-Dec-15 2015_12 FBgn0022332 fs(3)160 fs(3)160 http://flybase.net/reports/FBgn0022332.html gene fs160 16-Dec-15 2015_12 FBgn0030369 Cyp318a1 Cyp318a1 http://flybase.net/reports/FBgn0030369.html FBgn0030368 protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0004497=monooxygenase activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "cytochrome P450, 318a1, CG11364, Cyp318A1, CG1786" "IPR017972=Cytochrome P450, conserved site, IPR002403=Cytochrome P450, E-class, group IV, IPR001128=Cytochrome P450" CG1786 16-Dec-15 2015_12 YDR402C(DIT2) "viable,fertile" FBgn0021763 sim::trh sim::trh http://flybase.net/reports/FBgn0021763.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0036016 CG3306 http://flybase.net/reports/FBgn0036016.html protein_coding_gene IPR003409=MORN motif CG3306 16-Dec-15 2015_12 ENSDARG00000033610(morn5) ENSXETG00000016326(TEgg084k12.1) ENSMUSG00000026894(Morn5) ENSG00000185681(MORN5) viable FBgn0035667 Jon65Ai Jonah 65Ai http://flybase.net/reports/FBgn0035667.html FBgn0001286 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG10475, SP145, Jon65A, CT29408, Jon65, Jonah 65A" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG10475 16-Dec-15 2015_12 "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable DRSC24837 K -0.684455362 0.449427691 -0.174294669 0.176657859 -0.836945439 1.540782932 FBgn0060450 l(3)S120307 lethal (3) S120307 http://flybase.net/reports/FBgn0060450.html gene 1203/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060807 l(3)S055009a lethal (3) S055009a http://flybase.net/reports/FBgn0060807.html gene 0550/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0001381 l(1)2Bm lethal (1) 2Bm http://flybase.net/reports/FBgn0001381.html gene l(1)HC255 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0050446 Tdc2 Tyrosine decarboxylase 2 http://flybase.net/reports/FBgn0050446.html FBgn0033091 protein_coding_gene "0004837=tyrosine decarboxylase activity, 0030170=pyridoxal phosphate binding, 0004058=aromatic-L-amino-acid decarboxylase activity" "0018991=oviposition, 0045475=locomotor rhythm, 0007626=locomotory behavior, 0048148=behavioral response to cocaine, 0006520=cellular amino acid metabolic process" "dTdc2, TDC2, tyrosine decarboxylase, CG3686, CG30446, tyrosine decarboxylase 2, tdc, tdc2" "IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR021115=Pyridoxal-phosphate binding site, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR010977=Aromatic-L-amino-acid decarboxylase" CG30446 16-Dec-15 2015_12 WBGene00006562(tdc-1) "locomotor rhythm defective,female sterile,recessive,locomotor behavior defective,semidominant,chemosensitive behavior defective,mating behavior defective,female limited,courtship behavior defective,starvation stress response defective" "adult brain,multidendritic neuron,type II bouton,embryonic/larval neuromuscular junction" FBgn0046162 Doe Downstream of Eyeless http://flybase.net/reports/FBgn0046162.html gene 16-Dec-15 2015_12 FBgn0016957 tilN touch insensitive larva N http://flybase.net/reports/FBgn0016957.html gene line 301 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0027131 l(3)B6 lethal (3) B6 http://flybase.net/reports/FBgn0027131.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0051701 CG31701 http://flybase.net/reports/FBgn0051701.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035199 CG9134 http://flybase.net/reports/FBgn0035199.html protein_coding_gene 0030246=carbohydrate binding "IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG9134 16-Dec-15 2015_12 "ENSDARG00000008075(illr4),ENSDARG00000056379(si:ch211-154o6.6),ENSDARG00000046142(si:ch211-170d8.5),ENSDARG00000059049(zgc:174904)" ENSMUSG00000005540(Fcer2a) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032224 Sps2 Selenophosphate synthetase 2 http://flybase.net/reports/FBgn0032224.html protein_coding_gene "0004756=selenide, water dikinase activity, 0017076=purine nucleotide binding, 0005524=ATP binding" 0016260=selenocysteine biosynthetic process "sps2, dsps2, Dsps2, dSPS2, selenophosphate synthetase 2, CG5025, SPS2" "IPR004536=Selenophosphate synthetase, IPR010918=AIR synthase-related protein, C-terminal domain, IPR016188=PurM-like, N-terminal domain" CG5025 16-Dec-15 2015_12 " embryonic stage | stage 13 , adult stage && oogenesis stage , larval stage , embryonic stage | gastrula , embryonic stage | stage <= 5 , adult stage , embryonic stage " " embryonic nervous system

, nurse cell

, oocyte

, midgut primordium

, organism

, embryonic digestive system

" viable FBgn0020872 anon-P97 anon-P97 http://flybase.net/reports/FBgn0020872.html gene 2-P97 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0036377 CG10710 http://flybase.net/reports/FBgn0036377.html protein_coding_gene CG10710 16-Dec-15 2015_12 FBgn0045501 Gr22a Gustatory receptor 22a http://flybase.net/reports/FBgn0045501.html "FBgn0045490, FBgn0051662" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG31662, GR22a, Gustatory receptor 2940.5, Gr2940.5" IPR013604=7TM chemoreceptor CG31662 16-Dec-15 2015_12 DRSC22283 K -0.068837186 0.191432576 -0.327301367 0.007651483 0.154130124 1.602965159 FBgn0031231 mRpL10 mitochondrial ribosomal protein L10 http://flybase.net/reports/FBgn0031231.html protein_coding_gene 0003735=structural constituent of ribosome "0042254=ribosome biogenesis, 0006412=translation" "0005762=mitochondrial large ribosomal subunit, 0030529=ribonucleoprotein complex" "L10, CG11488" IPR001790=Ribosomal protein L10P CG11488 16-Dec-15 2015_12 ENSDARG00000045091(mrpl10) WBGene00010458(K01C8.6) ENSXETG00000014749(MRPL10) ENSMUSG00000001445(Mrpl10) ENSG00000159111(MRPL10) "viable,visible" trichogen cell FBgn0052451 SPoCk Secretory Pathway Calcium atpase http://flybase.net/reports/FBgn0052451.html "FBgn0037189, FBgn0037190, FBgn0062145" protein_coding_gene "0005388=calcium-transporting ATPase activity, 0046872=metal ion binding, 0000166=nucleotide binding, 0015410=manganese-transporting ATPase activity" "0051208=sequestering of calcium ion, 0042044=fluid transport, 0019722=calcium-mediated signaling, 0006816=calcium ion transport" "0012505=endomembrane system, 0005794=Golgi apparatus, 0016021=integral component of membrane, 0005783=endoplasmic reticulum, 0005777=peroxisome" "CG32451, anon-WO0118547.249, SPoCK, CG7651, CG14449" "IPR023299=P-type ATPase, cytoplasmic domain N, IPR023214=HAD-like domain, IPR006413=P-type ATPase, subfamily IIA, PMR1-type, IPR006068=Cation-transporting P-type ATPase, C-terminal, IPR004014=Cation-transporting P-type ATPase, N-terminal, IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR023298=P-type ATPase, transmembrane domain, IPR001757=P-type ATPase" CG32451 16-Dec-15 2015_12 ENSDARG00000060197 YGL167C(PMR1) WBGene00004063(pmr-1) ENSXETG00000002329(ATP2C1) ENSMUSG00000032570(Atp2c1) "ENSG00000017260(ATP2C1),ENSG00000064270(ATP2C2)" viable Malpighian tubule DRSC11706 E 0.263156096 -1.397511711 3.436917197 -1.088587593 0.541954827 0.046866632 FBgn0037761 CG8534 http://flybase.net/reports/FBgn0037761.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane IPR002076=ELO family CG8534 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0001408 l(1)3Bc lethal (1) 3Bc http://flybase.net/reports/FBgn0001408.html gene "l(1)zw12, zw12, zw-12, ZW-12" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone" "egg,germline clone,female reproductive system" FBgn0053881 His4:CG33881 His4:CG33881 http://flybase.net/reports/FBgn0053881.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33881 "IPR009072=Histone-fold, IPR001951=Histone H4, IPR019809=Histone H4, conserved site" CG33881 16-Dec-15 2015_12 "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) FBgn0028291 l(1)G0400 lethal (1) G0400 http://flybase.net/reports/FBgn0028291.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039864 CG11550 http://flybase.net/reports/FBgn0039864.html protein_coding_gene "IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG11550 16-Dec-15 2015_12 FBgn0004665 ms(3)HO5B male sterile (3) HO5B http://flybase.net/reports/FBgn0004665.html "FBgn0002835, FBgn0002837, FBgn0005314" gene "ms(3)m2, male sterile(3)m2, ms(3)ms2, ms(3)ms2[5A]" 16-Dec-15 2015_12 "male sterile,recessive" "testis,spermatozoon" FBgn0263831 Gen XPG-like endonuclease http://flybase.net/reports/FBgn0263831.html "FBgn0027914, FBgn0069101" protein_coding_gene "0008310=single-stranded DNA 3'-5' exodeoxyribonuclease activity, 0048256=flap endonuclease activity, 0003684=damaged DNA binding, 0004519=endonuclease activity, 0004520=endodeoxyribonuclease activity, 0000014=single-stranded DNA endodeoxyribonuclease activity, 0035312=5'-3' exodeoxyribonuclease activity, 0008311=double-stranded DNA 3'-5' exodeoxyribonuclease activity" "0006281=DNA repair, 0000737=DNA catabolic process, endonucleolytic, 0000738=DNA catabolic process, exonucleolytic, 0006302=double-strand break repair, 0006284=base-excision repair" 0005634=nucleus "mus324, BcDNA:GM10765, mutagen-sensitive 324, CG10670, DmGEN" "IPR020045=5'-3' exonuclease, C-terminal domain, IPR006085=XPG N-terminal, IPR029060=PIN domain-like, IPR006086=XPG-I domain, IPR008918=Helix-hairpin-helix motif, class 2, IPR006084=XPG/Rad2 endonuclease" CG10670 16-Dec-15 2015_12 YER041W(YEN1) WBGene00019004(xpg-1) ENSXETG00000015570(GEN1) ENSMUSG00000051235(Gen1) ENSG00000178295(GEN1) FBgn0083975 Nlg4 Neuroligin 4 http://flybase.net/reports/FBgn0083975.html "FBan0031499, FBgn0038776, FBgn0038777, FBgn0038778, FBgn0038779, FBgn0051209, FBgn0051499, FBgn0063732" protein_coding_gene "0004872=receptor activity, 0042043=neurexin family protein binding, 0052689=carboxylic ester hydrolase activity" "0030431=sleep, 0007416=synapse assembly, 0051932=synaptic transmission, GABAergic" "0045202=synapse, 0009986=cell surface, 0005887=integral component of plasma membrane" "CG5035, BcDNA:AT13703, dnlg4, CG5030, CG15683, CG31499, CG34139, CG15682, CG31209" "IPR002018=Carboxylesterase, type B, IPR019819=Carboxylesterase type B, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG34139 16-Dec-15 2015_12 "ENSDARG00000062376(nlgn3b),ENSDARG00000062581(nlgn3a)" WBGene00013540(Y75B8A.3) "ENSXETG00000020891(NLGN3),ENSXETG00000021425(),ENSXETG00000001525(NLGN1),ENSXETG00000023971(NLGN2)" "ENSMUSG00000063887(Nlgn1),ENSMUSG00000031302(Nlgn3),ENSMUSG00000051790(Nlgn2)" "ENSG00000146938(NLGN4X),ENSG00000196338(NLGN3),ENSG00000165246(NLGN4Y),ENSG00000169760(NLGN1),ENSG00000169992(NLGN2)" "lethal,sleep defective,heat sensitive,neuroanatomy defective,neurophysiology defective,viable,visible" "l-LNv neuron,trichogen cell" DRSC22243 IE 1.558935339 -2.039759475 1.667793225 -1.05426555 0.126635893 0.599242554 FBgn0026737 CG6171 http://flybase.net/reports/FBgn0026737.html protein_coding_gene "0008408=3'-5' exonuclease activity, 0003906=DNA-(apurinic or apyrimidinic site) lyase activity, 0004520=endodeoxyribonuclease activity" "0090305=nucleic acid phosphodiester bond hydrolysis, 0000737=DNA catabolic process, endonucleolytic, 0000012=single strand break repair, 0006302=double-strand break repair" 0005634=nucleus "anon-Becker2, Anon-becker2, unnamed" "IPR019406=Zinc finger, C2H2, APLF-like" CG6171 16-Dec-15 2015_12 viable FBgn0085542 CG40949 http://flybase.net/reports/FBgn0085542.html FBan0040949 protein_coding_gene 16-Dec-15 2015_12 FBgn0001673 l(1)EN10a lethal (1) from Eugene Nonautonomous 10a http://flybase.net/reports/FBgn0001673.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0264381 CR43833 http://flybase.net/reports/FBgn0264381.html non_protein_coding_gene CR43833 16-Dec-15 2015_12 FBgn0005215 l(3)ET6 lethal Elaine Tasaka 6 http://flybase.net/reports/FBgn0005215.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0033110 CG9447 http://flybase.net/reports/FBgn0033110.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" IPR002656=Acyltransferase 3 CG9447 16-Dec-15 2015_12 viable FBgn0066343 lis lis http://flybase.net/reports/FBgn0066343.html gene "0008355=olfactory learning, 0007611=learning or memory" 16-Dec-15 2015_12 memory defective FBgn0015888 anon-6Eb anon-6Eb http://flybase.net/reports/FBgn0015888.html gene 16-Dec-15 2015_12 FBgn0022176 l(2)k05416 lethal (2) k05416 http://flybase.net/reports/FBgn0022176.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003157 pte pterygion http://flybase.net/reports/FBgn0003157.html gene 16-Dec-15 2015_12 "viable,reduced,visible,recessive" "wing,eye,adult abdomen" FBgn0012024 tRNA:Y1:85Aa transfer RNA:tyr1:85Aa http://flybase.net/reports/FBgn0012024.html "FBgn0003849, FBgn0012014, FBgn0051435, FBgn0060005" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA-Tyr, Tyr-tRNA T85a, 85Aa, CR31435, tRNA[Tyr][[1gamma]], tRNA:Y, AE002708.trna57-TyrGTA, tRNA:Y:GTA:AE002708-a, chr3R.trna63-TyrGTA, tRNA[Tyr], tRNA:tyr1:85Aa" CR31435 16-Dec-15 2015_12 FBgn0084972 l(3)S016805 l(3)S016805 http://flybase.net/reports/FBgn0084972.html gene 16-Dec-15 2015_12 FBgn0036527 CG7304 http://flybase.net/reports/FBgn0036527.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity "0009312=oligosaccharide biosynthetic process, 0032504=multicellular organism reproduction" dppGalNAcT11 "IPR001173=Glycosyltransferase 2-like, IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain" CG7304 16-Dec-15 2015_12 "viable,fertile" FBgn0029657 CG12535 http://flybase.net/reports/FBgn0029657.html protein_coding_gene CG12535 16-Dec-15 2015_12 FBgn0035249 CG17249 http://flybase.net/reports/FBgn0035249.html protein_coding_gene IPR018800=Proline-rich protein PRCC CG17249 16-Dec-15 2015_12 ENSDARG00000063252(prcc) WBGene00008034(C39E9.11) ENSXETG00000018517(PRCC) ENSMUSG00000004895(Prcc) ENSG00000143294(PRCC) viable FBgn0011218 emm emmenthal http://flybase.net/reports/FBgn0011218.html gene 0007286=spermatid development ms(2)06268 16-Dec-15 2015_12 "male sterile,recessive" Nebenkern FBgn0024984 CG3457 http://flybase.net/reports/FBgn0024984.html protein_coding_gene EG:17E2.1 CG3457 16-Dec-15 2015_12 "viable,fertile" FBgn0020525 mit(3)r135 mitotic r135 http://flybase.net/reports/FBgn0020525.html gene 16-Dec-15 2015_12 FBgn0014180 grb gorbun http://flybase.net/reports/FBgn0014180.html gene gor 16-Dec-15 2015_12 FBgn0267275 CR45711 http://flybase.net/reports/FBgn0267275.html non_protein_coding_gene lincRNA.1017 CR45711 16-Dec-15 2015_12 FBgn0035089 Phk-3 Pherokine 3 http://flybase.net/reports/FBgn0035089.html FBgn0047170 protein_coding_gene "0009617=response to bacterium, 0007552=metamorphosis" "0005576=extracellular region, 0005615=extracellular space" "CG9358, BcDNA:RE09339, PHK-3, DmelCSP3" IPR005055=Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG9358 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0027958 l(3)S147913 lethal (3) S147913 http://flybase.net/reports/FBgn0027958.html gene 1479/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0051406 CG31406 http://flybase.net/reports/FBgn0051406.html FBgn0065012 protein_coding_gene 0048802=notum morphogenesis BcDNA:AT13367 CG31406 16-Dec-15 2015_12 "viable,visible,lethal - all die before end of P-stage,some die during pharate adult stage" "trichogen cell,scutellum" FBgn0021881 l(2)k13506 lethal (2) k13506 http://flybase.net/reports/FBgn0021881.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002430 l(3)F60 lethal (3) F60 http://flybase.net/reports/FBgn0002430.html gene l(3)60 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,scutum" FBgn0011473 l(3)neo40 lethal (3) neo40 http://flybase.net/reports/FBgn0011473.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067672 omelet omelet http://flybase.net/reports/FBgn0067672.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0070047 3L-215-13 3L-215-13 http://flybase.net/reports/FBgn0070047.html gene 0030703=eggshell formation 16-Dec-15 2015_12 "egg,germline clone,non-rescuable maternal effect,dorsal appendage,maternal effect" FBgn0031645 CG3036 http://flybase.net/reports/FBgn0031645.html protein_coding_gene 0005436=sodium:phosphate symporter activity "0006817=phosphate ion transport, 0055085=transmembrane transport" "0016021=integral component of membrane, 0005886=plasma membrane" "CT10168, 151989_at" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG3036 16-Dec-15 2015_12 "YOR378W(),YML116W(ATR1),YMR279C()" viable rhabdomere R7 FBgn0036262 CG6910 http://flybase.net/reports/FBgn0036262.html protein_coding_gene "0005506=iron ion binding, 0050113=inositol oxygenase activity" "0055114=oxidation-reduction process, 0019310=inositol catabolic process" 0005737=cytoplasm IPR007828=Inositol oxygenase CG6910 16-Dec-15 2015_12 ENSDARG00000002764(miox) WBGene00016920(C54E4.5) ENSXETG00000023087(Q5M8X0_XENTR) ENSMUSG00000022613(Miox) ENSG00000100253(MIOX) "viable,fertile" FBgn0027115 mei-P37 mei-P37 http://flybase.net/reports/FBgn0027115.html gene 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0010301 fs(2)lto3 female sterile (2) lto3 http://flybase.net/reports/FBgn0010301.html "FBgn0000990, FBgn0000991, FBgn0004802" gene "0046843=dorsal appendage formation, 0048477=oogenesis" "fs(2)ltoRE57, fs(2)lo-C" 16-Dec-15 2015_12 female sterile FBgn0040751 CG13018 http://flybase.net/reports/FBgn0040751.html protein_coding_gene IPR018793=Cytochrome c oxidase assembly protein PET191 CG13018 16-Dec-15 2015_12 ENSDARG00000070125(zgc:153408) WBGene00012483(Y18D10A.16) ENSXETG00000026562(TGas128e22.1) ENSMUSG00000026112(6330578E17Rik) ENSG00000183513(COA5) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0070021 BG00977 BG00977 http://flybase.net/reports/FBgn0070021.html gene 16-Dec-15 2015_12 stress response defective FBgn0031856 CG11322 http://flybase.net/reports/FBgn0031856.html protein_coding_gene IPR006640=SprT-like CG11322 16-Dec-15 2015_12 ENSG00000147174(ACRC) viable FBgn0017485 Su(var)315 Suppressor of variegation 315 http://flybase.net/reports/FBgn0017485.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable" FBgn0033608 CG13220 http://flybase.net/reports/FBgn0033608.html protein_coding_gene CG13220 16-Dec-15 2015_12 FBgn0053498 CR33498 http://flybase.net/reports/FBgn0053498.html pseudogene_attribute CG33498 CR33498 16-Dec-15 2015_12 "ENSDARG00000053593(LOC100329372),ENSDARG00000013335(LOC100333447)" FBgn0082596 drmo-o57 drymouth o57 http://flybase.net/reports/FBgn0082596.html gene 0046903=secretion 16-Dec-15 2015_12 FBgn0024855 l(3)96Bg lethal (3) 96Bg http://flybase.net/reports/FBgn0024855.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028216 l(3)S008418 lethal (3) S008418 http://flybase.net/reports/FBgn0028216.html gene "1398/10, 0092/23, 0084/18, 1193/13, 0256/37, 1483/18" 16-Dec-15 2015_12 "lethal,recessive" FBgn0043871 nompF no mechanoreceptor potential F http://flybase.net/reports/FBgn0043871.html gene 0007605=sensory perception of sound 16-Dec-15 2015_12 "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0034206 CG18469 http://flybase.net/reports/FBgn0034206.html FBgn0061439 protein_coding_gene BcDNA:AT30190 CG18469 16-Dec-15 2015_12 viable FBgn0015958 l(1)m-C lethal (1) m-Caggese http://flybase.net/reports/FBgn0015958.html gene 16-Dec-15 2015_12 lethal FBgn0051015 PH4ë±PV prolyl-4-hydroxylase-alpha PV http://flybase.net/reports/FBgn0051015.html FBgn0039793 protein_coding_gene "0005506=iron ion binding, 0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" "0055114=oxidation-reduction process, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" "CG31015, PH4alphaPV, CG9713" "IPR011990=Tetratricopeptide-like helical domain, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG31015 16-Dec-15 2015_12 viable FBgn0054026 CG34026 http://flybase.net/reports/FBgn0054026.html FBgn0082842 protein_coding_gene "BP1064, unnamed" CG34026 16-Dec-15 2015_12 FBgn0265593 CR44420 http://flybase.net/reports/FBgn0265593.html non_protein_coding_gene CR44420 16-Dec-15 2015_12 FBgn0263089 CR43357 http://flybase.net/reports/FBgn0263089.html non_protein_coding_gene CR43357 16-Dec-15 2015_12 FBgn0267082 CR45526 http://flybase.net/reports/FBgn0267082.html non_protein_coding_gene CR45526 16-Dec-15 2015_12 FBgn0067084 M8 M8 http://flybase.net/reports/FBgn0067084.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0037453 CG10690 http://flybase.net/reports/FBgn0037453.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033241 CG2915 http://flybase.net/reports/FBgn0033241.html protein_coding_gene "0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" 0006508=proteolysis "0012505=endomembrane system, 0005576=extracellular region, 0031982=vesicle" "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG2915 16-Dec-15 2015_12 YHR132C(ECM14) "WBGene00020283(T06A4.3),WBGene00011235(R11A5.7),WBGene00021645(Y47G6A.19)" ENSXETG00000016293() viable FBgn0065606 l(2)SH0848 lethal (2) SH0848 http://flybase.net/reports/FBgn0065606.html gene l(2)SH2 0848 16-Dec-15 2015_12 "lethal,recessive" FBgn0261740 b6-22 http://flybase.net/reports/FBgn0261740.html gene "0040034=regulation of development, heterochronic" 16-Dec-15 2015_12 developmental rate defective FBgn0082960 snoRNA:ë¬28S-3405a snoRNA:ë¬28S-3405a http://flybase.net/reports/FBgn0082960.html snoRNA_gene "Psi 28S-3405a, CR34618, psi28s-3405a" CR34618 16-Dec-15 2015_12 FBgn0060419 l(3)S129114 lethal (3) S129114 http://flybase.net/reports/FBgn0060419.html gene 1291/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266813 CR45275 http://flybase.net/reports/FBgn0266813.html non_protein_coding_gene CR45275 16-Dec-15 2015_12 FBgn0038579 CG14313 http://flybase.net/reports/FBgn0038579.html protein_coding_gene CG14313 16-Dec-15 2015_12 viable FBgn0264077 Cnx14D Calnexin 14D http://flybase.net/reports/FBgn0264077.html "FBgn0028466, FBgn0030755" protein_coding_gene "0051082=unfolded protein binding, 0005509=calcium ion binding" 0006457=protein folding "0005789=endoplasmic reticulum membrane, 0005783=endoplasmic reticulum" "Cnx, CG9906, Calnexin, Xcbp1" "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR009033=Calreticulin/calnexin, P domain, IPR018124=Calreticulin/calnexin, conserved site, IPR001580=Calreticulin/calnexin" CG9906 16-Dec-15 2015_12 "ENSDARG00000037488(canx),ENSDARG00000009315(clgn)" YAL058W(CNE1) WBGene00000567(cnx-1) ENSXETG00000008408(canx) "ENSMUSG00000020368(Canx),ENSMUSG00000002190(Clgn)" "ENSG00000127022(CANX),ENSG00000153132(CLGN)" FBgn0065529 l(2)SH1112 lethal (2) SH1112 http://flybase.net/reports/FBgn0065529.html gene l(2)SH2 1112 16-Dec-15 2015_12 "lethal,recessive" FBgn0037950 HisCl1 Histamine-gated chloride channel subunit 1 http://flybase.net/reports/FBgn0037950.html protein_coding_gene "0019182=histamine-gated chloride channel activity, 0016933=extracellular-glycine-gated ion channel activity" "0043052=thermotaxis, 0006821=chloride transport" "0019183=histamine-gated chloride channel complex, 0016021=integral component of membrane" "DMHisClalpha2, HA-CI II, CG14723, hisCl1, histamine-gated chloride channel subunit 1, CT34515, glycine receptor alpha3 subunit-like, hclB, HisCl-alpha2, DmHisCl1, Dm-HCLB" "IPR006201=Neurotransmitter-gated ion-channel, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha" CG14723 16-Dec-15 2015_12 "chemical resistant,neurophysiology defective,paralytic,heat sensitive,chemical sensitive,partially lethal - majority die,some die during pupal stage,viable,thermotaxis behavior defective,recessive,lethal" FBgn0264711 CG43980 http://flybase.net/reports/FBgn0264711.html "FBgn0053291, FBgn0037113, FBgn0053292" protein_coding_gene 0046982=protein heterodimerization activity "CG33292, CG11250, CG33291" "IPR002110=Ankyrin repeat, IPR009072=Histone-fold, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR020683=Ankyrin repeat-containing domain" CG43980 16-Dec-15 2015_12 "ENSDARG00000063255(btbd11a),ENSDARG00000063040(LOC559730),ENSDARG00000059751(LOC559451),ENSDARG00000062000" "ENSXETG00000003783(Q640A3_XENTR),ENSXETG00000016964()" "ENSMUSG00000032724(Abtb2),ENSMUSG00000020042(Btbd11)" "ENSG00000151136(BTBD11),ENSG00000166016(ABTB2)" DRSC11500 E 0.174452997 0.294712213 2.434766404 0.083883545 0.39343533 -0.528620544 FBgn0265154 Ir60f Ionotropic receptor 60f http://flybase.net/reports/FBgn0265154.html pseudogene_attribute "CR44223, DmelIR60f" CR44223 16-Dec-15 2015_12 FBgn0265686 CR44493 http://flybase.net/reports/FBgn0265686.html non_protein_coding_gene CR44493 16-Dec-15 2015_12 FBgn0027782 Su(y)P22 Su(y)P22 http://flybase.net/reports/FBgn0027782.html gene Su(y)[P22] 16-Dec-15 2015_12 FBgn0037126 CG14567 http://flybase.net/reports/FBgn0037126.html protein_coding_gene CG14567 16-Dec-15 2015_12 viable FBgn0243498 l(2)CA07436 http://flybase.net/reports/FBgn0243498.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0266771 CR45236 http://flybase.net/reports/FBgn0266771.html non_protein_coding_gene CR45236 16-Dec-15 2015_12 FBgn0031299 CG4629 http://flybase.net/reports/FBgn0031299.html FBgn0063800 protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0007155=cell adhesion, 0006468=protein phosphorylation, 0008360=regulation of cell shape" anon-WO0257455.15 "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG4629 16-Dec-15 2015_12 WBGene00009867(F49C5.4) "ENSMUSG00000079302,ENSMUSG00000079833" ENSG00000177453(NIM1) viable FBgn0034360 CG10927 http://flybase.net/reports/FBgn0034360.html protein_coding_gene "0008270=zinc ion binding, 0016787=hydrolase activity" "IPR016193=Cytidine deaminase-like, IPR002125=Cytidine and deoxycytidylate deaminases, zinc-binding" CG10927 16-Dec-15 2015_12 ENSDARG00000005640(si:dkey-204g5.2) WBGene00012927(Y47D3A.14) ENSXETG00000006617(ADAT3) ENSMUSG00000035370(Scamp4) ENSG00000213638(ADAT3) viable FBgn0028096 l(3)S074606b lethal (3) S074606b http://flybase.net/reports/FBgn0028096.html gene "0746/06, l(3)S074606" 16-Dec-15 2015_12 "lethal,recessive" FBgn0030163 CG1791 http://flybase.net/reports/FBgn0030163.html protein_coding_gene "Fibrinogen-related protein, AAF46535, FBpp0071364, AAM52597" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG1791 16-Dec-15 2015_12 "ENSDARG00000068369(angptl2),ENSDARG00000024030(zgc:194138),ENSDARG00000020265(angptl6),ENSDARG00000027582(angptl7)" "WBGene00016769(C49C8.5),WBGene00012782(Y43C5A.2)" "ENSMUSG00000004105(Angptl2),ENSMUSG00000033544(Angptl1),ENSMUSG00000038742(Angptl6)" "ENSG00000136859(ANGPTL2),ENSG00000130812(ANGPTL6)" viable DRSC29301 K -0.094167122 -0.129779061 0.387101592 -0.108230934 -0.523416556 3.118458144 FBgn0034467 CG15128 http://flybase.net/reports/FBgn0034467.html protein_coding_gene "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG15128 16-Dec-15 2015_12 viable FBgn0027190 l(2)60A-B lethal (2) 60A-B http://flybase.net/reports/FBgn0027190.html gene 16-Dec-15 2015_12 lethal FBgn0002276 l(3)73Aa lethal (3) 73Aa http://flybase.net/reports/FBgn0002276.html gene l(3)std6 16-Dec-15 2015_12 "lethal,recessive" FBgn0261287 ymp yellow-emperor http://flybase.net/reports/FBgn0261287.html "FBgn0028553, FBgn0039345, FBgn0063360" protein_coding_gene "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "BcDNA:AT03213, CG12250" CG12250 16-Dec-15 2015_12 FBgn0026326 Mad1 http://flybase.net/reports/FBgn0026326.html protein_coding_gene "0007094=mitotic spindle assembly checkpoint, 0051315=attachment of mitotic spindle microtubules to kinetochore" "0072686=mitotic spindle, 0005635=nuclear envelope, 0000776=kinetochore, 0005654=nucleoplasm" "Mad1, TXBP181-like, CG2072, mad1" IPR008672=Spindle assembly checkpoint component Mad1 CG2072 16-Dec-15 2015_12 ENSDARG00000033852(mad1l1) ENSXETG00000022997(mad1l1) ENSMUSG00000029554(Mad1l1) ENSG00000002822(MAD1L1) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0033751 CG8818 http://flybase.net/reports/FBgn0033751.html protein_coding_gene CG8818 16-Dec-15 2015_12 viable FBgn0086386 BG01672 http://flybase.net/reports/FBgn0086386.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0001590 l(1)carot7 lethal (1) carot7 http://flybase.net/reports/FBgn0001590.html gene 16-Dec-15 2015_12 lethal FBgn0035632 Ppat-Dpck Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase http://flybase.net/reports/FBgn0035632.html protein_coding_gene "0004595=pantetheine-phosphate adenylyltransferase activity, 0005524=ATP binding, 0004140=dephospho-CoA kinase activity" "0007303=cytoplasmic transport, nurse cell to oocyte, 0007297=ovarian follicle cell migration, 0007476=imaginal disc-derived wing morphogenesis, 0015937=coenzyme A biosynthetic process, 0070328=triglyceride homeostasis" "CG10575, dPPAT-DPCK, 4'-phosphopantetheine adenylyltransferase - dephospho-CoA kinase, PPAT-DPCK, DPCK/PPAT" "IPR004821=Cytidyltransferase-like domain, IPR001977=Dephospho-CoA kinase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10575 16-Dec-15 2015_12 ENSDARG00000042747(zgc:92337) WBGene00022031(Y65B4A.8) ENSXETG00000012037(COASY) ENSMUSG00000001755(Coasy) ENSG00000068120(COASY) "locomotor behavior defective,paralytic,heat sensitive,female sterile,partially,recessive,flightless,flight defective,short lived,visible,chemical sensitive,radiation sensitive,increased cell death,sterile,viable" "wing,embryonic/larval brain,wing vein,ectopic,egg,maternal effect,egg chamber,follicle cell,lipid droplet & egg chamber" FBgn0070014 BG01130 BG01130 http://flybase.net/reports/FBgn0070014.html gene 0002121=inter-male aggressive behavior 16-Dec-15 2015_12 "stress response defective,behavior defective,recessive" FBgn0034700 CG11269 http://flybase.net/reports/FBgn0034700.html protein_coding_gene 0004521=endoribonuclease activity 0009303=rRNA transcription IPR026770=Ribonuclease kappa CG11269 16-Dec-15 2015_12 viable FBgn0015968 l(2)55BCa lethal (2) 55BCa http://flybase.net/reports/FBgn0015968.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266909 CR45369 http://flybase.net/reports/FBgn0266909.html non_protein_coding_gene CR45369 16-Dec-15 2015_12 FBgn0030658 CG7872 http://flybase.net/reports/FBgn0030658.html protein_coding_gene 0012505=endomembrane system "IPR018253=DnaJ domain, conserved site, IPR001623=DnaJ domain" CG7872 16-Dec-15 2015_12 ENSDARG00000067613(si:ch211-154e10.2) "WBGene00001020(dnj-2),WBGene00008122(C47A4.1)" ENSMUSG00000070972(Dnajc25) ENSG00000059769(DNAJC25) "viable,fertile" FBgn0046842 ird26 immune response deficient 26 http://flybase.net/reports/FBgn0046842.html gene 0006959=humoral immune response 16-Dec-15 2015_12 "lethal,recessive,immune response defective" FBgn0261986 RASSF8 http://flybase.net/reports/FBgn0261986.html "FBgn0039352, FBgn0086725" protein_coding_gene "0048749=compound eye development, 0040015=negative regulation of multicellular organism growth, 0007165=signal transduction, 0033227=dsRNA transport" 0005912=adherens junction "dmRASSF7/8, dRASSF8, Boa, CG5053" "IPR029071=Ubiquitin-related domain, IPR000159=Ras-associating (RA) domain" CG5053 16-Dec-15 2015_12 "ENSDARG00000045485(rassf8b),ENSDARG00000045596(LOC100003291)" WBGene00019403(K05B2.2) "ENSXETG00000023490(RASSF8),ENSXETG00000006038(RASSF7)" ENSMUSG00000030259(Rassf8) ENSG00000123094(RASSF8) FBgn0022231 l(2)k03003 lethal (2) k03003 http://flybase.net/reports/FBgn0022231.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261536 CG42660 http://flybase.net/reports/FBgn0261536.html protein_coding_gene CG42660 16-Dec-15 2015_12 FBgn0016895 l(3)64Ce lethal (3) 64Ce http://flybase.net/reports/FBgn0016895.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263402 CG43448 http://flybase.net/reports/FBgn0263402.html protein_coding_gene lincRNA.898 CG43448 16-Dec-15 2015_12 FBgn0027249 l(1)G0259 lethal (1) G0259 http://flybase.net/reports/FBgn0027249.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028534 CG7916 http://flybase.net/reports/FBgn0028534.html protein_coding_gene "LP05416, CT23894, BG:DS00941.13" IPR010562=Haemolymph juvenile hormone binding CG7916 16-Dec-15 2015_12 viable FBgn0051851 CG31851 http://flybase.net/reports/FBgn0051851.html FBgn0032496 protein_coding_gene 0008080=N-acetyltransferase activity CG16821 "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG31851 16-Dec-15 2015_12 "viable,fertile" FBgn0062440 CG17680 http://flybase.net/reports/FBgn0062440.html FBgn0034303 protein_coding_gene "0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium" BcDNA:RE55001 IPR018782=Uncharacterised protein family UPF0466 CG17680 16-Dec-15 2015_12 ENSXETG00000027338(TNeu133h13.1) ENSMUSG00000022452(1500032L24Rik) ENSG00000183172(C22orf32) "lethal,body color defective" mesothoracic tergum FBgn0001439 l(1)7Ca lethal (1) 7Ca http://flybase.net/reports/FBgn0001439.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001587 l(1)carot4 lethal (1) carot4 http://flybase.net/reports/FBgn0001587.html gene 16-Dec-15 2015_12 lethal FBgn0034865 Or59b Odorant receptor 59b http://flybase.net/reports/FBgn0034865.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR119, 59E.1, DmOR59B, CG3569, 59b" "IPR004117=Olfactory receptor, Drosophila" CG3569 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0039584 beat-VI beat-VI http://flybase.net/reports/FBgn0039584.html FBgn0039583 protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules "0031225=anchored component of membrane, 0005576=extracellular region" "Beat-VI, CG12089, CG14064, beat VI" "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain, IPR013106=Immunoglobulin V-set domain" CG14064 16-Dec-15 2015_12 "ENSDARG00000068114(si:ch211-89p1.1),ENSDARG00000017320(f11r),ENSDARG00000058996,ENSDARG00000061794(jam3),ENSDARG00000063421" viable FBgn0026612 A69 A69 http://flybase.net/reports/FBgn0026612.html gene 16-Dec-15 2015_12 FBgn0032287 CG6415 http://flybase.net/reports/FBgn0032287.html FBgn0024715 protein_coding_gene 0004047=aminomethyltransferase activity 0006546=glycine catabolic process "0005960=glycine cleavage complex, 0005811=lipid particle" "unnamed, 151967_at, anon-32Aa" "IPR028896=Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA, IPR029043=Glycine cleavage T-protein/YgfZ, C-terminal domain, IPR006222=Glycine cleavage T-protein-like, N-terminal, IPR006223=Glycine cleavage system T protein, IPR027266=GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1, IPR013977=Glycine cleavage T-protein, C-terminal barrel domain" CG6415 16-Dec-15 2015_12 ENSDARG00000010862(amt) YDR019C(GCV1) WBGene00017765(F25B4.1) ENSXETG00000005937(AMT) ENSMUSG00000032607(Amt) ENSG00000145020(AMT) FBgn0019803 l(1)01 lethal (1) 01 http://flybase.net/reports/FBgn0019803.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0043368 EP1523 EP1523 http://flybase.net/reports/FBgn0043368.html gene 16-Dec-15 2015_12 visible "scutellar bristle,ectopic" FBgn0004832 Xpac Xeroderma pigmentosum group A-like http://flybase.net/reports/FBgn0004832.html protein_coding_gene 0003684=damaged DNA binding 0006289=nucleotide-excision repair 0005634=nucleus "DhR14, XPAC, Xpa, EG:EG0007.8, dmXPA, dxpa, DhXPA, DmXPA, CG6358, Dxpa, XPA_DROME" "IPR022656=XPA C- terminal, IPR000465=XPA, IPR022652=Zinc finger, XPA-type, conserved site, IPR022658=XPA, conserved site, IPR009061=Putative DNA-binding domain" CG6358 16-Dec-15 2015_12 YMR201C(RAD14) WBGene00006963(xpa-1) ENSXETG00000010181(XPA) ENSMUSG00000028329(Xpa) ENSG00000136936(XPA) " embryonic stage , adult stage , pupal stage | mid , larval stage | third instar , pupal stage | early " " adult stage , embryonic stage " " muscle cell

, lamina

, retina

, adult central nervous system

, ventral nerve cord

" viable FBgn0003962 us undersized http://flybase.net/reports/FBgn0003962.html gene 16-Dec-15 2015_12 "visible,viable,fertile" FBgn0035847 mthl7 methuselah-like 7 http://flybase.net/reports/FBgn0035847.html "FBgn0046502, FBgn0046503" protein_coding_gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0042594=response to starvation, 0008340=determination of adult lifespan" 0016021=integral component of membrane "mth-like 7, Mth-like 7, anon-WO0170980.85, anon-WO0170980.86, CG7476" "IPR023311=Methuselah ectodomain, domain 2, IPR017981=GPCR, family 2-like, IPR010596=Methuselah, N-terminal domain" CG7476 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" viable FBgn0036219 CCDC151 Coiled-coil domain containing protein 151 http://flybase.net/reports/FBgn0036219.html protein_coding_gene "0070286=axonemal dynein complex assembly, 0003341=cilium movement, 0048060=negative gravitaxis" "0031514=motile cilium, 0097542=ciliary tip, 0035253=ciliary rootlet, 0044297=cell body" "CG14127, Ccdc151" CG14127 16-Dec-15 2015_12 ENSDARG00000062978(zgc:152917) ENSXETG00000016745(CCDC151) ENSMUSG00000039632(Ccdc151) ENSG00000198003(CCDC151) "bang sensitive,gravitaxis defective,viable" FBgn0053392 5SrRNA:CR33392 5SrRNA:CR33392 http://flybase.net/reports/FBgn0053392.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33392 CR33392 16-Dec-15 2015_12 FBgn0053257 CG33257 http://flybase.net/reports/FBgn0053257.html FBgn0036613 protein_coding_gene CG13037 IPR007999=Protein of unknown function DUF745 CG33257 16-Dec-15 2015_12 FBgn0065687 l(2)SH0650 lethal (2) SH0650 http://flybase.net/reports/FBgn0065687.html gene l(2)SH2 0650 16-Dec-15 2015_12 "lethal,recessive" FBgn0265759 CR44566 http://flybase.net/reports/FBgn0265759.html non_protein_coding_gene lincRNA.591 CR44566 16-Dec-15 2015_12 FBgn0033596 CG7738 http://flybase.net/reports/FBgn0033596.html "FBgn0062932, FBtr0088110, FBpp0087211" protein_coding_gene 0006959=humoral immune response 0005615=extracellular space BcDNA:RH51528 16-Dec-15 2015_12 FBgn0002663 mat(2)cell-L maternal effect cellularisation defect L http://flybase.net/reports/FBgn0002663.html gene 0007349=cellularization mat(2)cellRQ41 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" "stage 5 embryo,embryonic/first instar larval cuticle" FBgn0085340 CR34311 http://flybase.net/reports/FBgn0085340.html pseudogene_attribute CR34311 16-Dec-15 2015_12 FBgn0019679 mor(1)12 mortality gene (1)12 http://flybase.net/reports/FBgn0019679.html gene 16-Dec-15 2015_12 short lived FBgn0262730 CG14446 http://flybase.net/reports/FBgn0262730.html "FBgn0029850, FBgn0086535" protein_coding_gene "lincRNA.S8753, mRNA-like ncRNA in embryogenesis 2, MRE2" IPR026307=Transmembrane protein 132 CG14446 16-Dec-15 2015_12 ENSDARG00000038671 WBGene00022175(Y71H2AM.10) "ENSXETG00000017649(TMEM132E),ENSXETG00000023736(TMEM132D),ENSXETG00000022175(TMEM132C)" "ENSMUSG00000020701(Tmem132e),ENSMUSG00000034324(Tmem132c),ENSMUSG00000034310(Tmem132d),ENSMUSG00000024736(Tmem132a)" "ENSG00000139364(TMEM132B),ENSG00000151952(TMEM132D),ENSG00000181234(TMEM132C),ENSG00000181291(TMEM132E),ENSG00000006118(TMEM132A)" FBgn0010220 Dbp45A DEAD box protein 45A http://flybase.net/reports/FBgn0010220.html protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "dbp45A, CG12759, DBP45A, ATP-dependent RNA helicase, Dbp45, DmRH18" "IPR014014=RNA helicase, DEAD-box type, Q motif, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG12759 16-Dec-15 2015_12 ENSDARG00000012899(ddx49) YHR169W(DBP8) ENSXETG00000010135(ddx49) ENSMUSG00000057788(Ddx49) ENSG00000105671(DDX49) embryonic stage -- adult stage "viable,visible" "trichogen cell,mesothoracic tergum" DRSC07395 I -1.509884774 0.827415492 -0.432689055 -0.380810194 0.449817345 0.564759769 FBgn0003874 tu(1)53 tumor(1)53 http://flybase.net/reports/FBgn0003874.html gene tu-53l 16-Dec-15 2015_12 "melanotic mass phenotype,partially lethal - majority die,developmental rate defective" wing FBgn0041256 E(csw)3B E(csw)3B http://flybase.net/reports/FBgn0041256.html gene 0002168=instar larval development 16-Dec-15 2015_12 FBgn0031351 CG14352 http://flybase.net/reports/FBgn0031351.html protein_coding_gene "IPR001005=SANT/Myb domain, IPR028002=Myb/SANT-like DNA-binding domain" CG14352 16-Dec-15 2015_12 viable FBgn0031182 Cyp6t1 Cyp6t1 http://flybase.net/reports/FBgn0031182.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "6t1, cytochrome P450, CG1644" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG1644 16-Dec-15 2015_12 YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "viable,fertile" FBgn0028686 Rpt3 Regulatory particle triple-A ATPase 3 http://flybase.net/reports/FBgn0028686.html FBgn0026699 protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity, 0016787=hydrolase activity" "0030163=protein catabolic process, 0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0001673=male germ cell nucleus, 0008540=proteasome regulatory particle, base subcomplex, 0005838=proteasome regulatory particle, 0005737=cytoplasm" "Dm_Rpt3a, TBP7, l(1)G0052, S6, p48A, Rpt3, Dmp48A, 16916, CG16916, S6B" "IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR005937=26S proteasome subunit P45, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001270=ClpA/B family" CG16916 16-Dec-15 2015_12 ENSDARG00000027099(psmc4) YDR394W(RPT3) WBGene00004503(rpt-3) ENSXETG00000014266(Psmc4) ENSMUSG00000030603(Psmc4) ENSG00000013275(PSMC4) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" DRSC20283 IEK -3.267273407 -3.960803336 -3.571212589 -3.382874364 0.764042517 -1.693399715 FBgn0042173 CG18853 http://flybase.net/reports/FBgn0042173.html protein_coding_gene 0003904=deoxyribodipyrimidine photo-lyase activity 0006281=DNA repair "CG18853-PA, 143303_at" "IPR001378=Uncharacterised domain UPF0066, IPR023370=TsaA-like domain, IPR008148=DNA photolyase, class 2, IPR005101=Cryptochrome/photolyase FAD-binding domain" CG18853 16-Dec-15 2015_12 "viable,fertile" DRSC20757 K -0.87766115 0.463158151 0.492163446 -0.752932001 -1.920071978 -1.708189136 FBgn0027978 l(3)S138815 lethal (3) S138815 http://flybase.net/reports/FBgn0027978.html gene 1388/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037910 CG14708 http://flybase.net/reports/FBgn0037910.html protein_coding_gene CG14708 16-Dec-15 2015_12 viable FBgn0266629 CR45136 http://flybase.net/reports/FBgn0266629.html non_protein_coding_gene CR45136 16-Dec-15 2015_12 FBgn0265318 CR44291 http://flybase.net/reports/FBgn0265318.html non_protein_coding_gene CR44291 16-Dec-15 2015_12 FBgn0033243 CG14763 http://flybase.net/reports/FBgn0033243.html protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement "0005875=microtubule associated complex, 0030286=dynein complex" IPR005334=Tctex-1 CG14763 16-Dec-15 2015_12 viable FBgn0035780 CG18417 http://flybase.net/reports/FBgn0035780.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis carboxypeptidase b1 "IPR000834=Peptidase M14, carboxypeptidase A, IPR009020=Proteinase inhibitor, propeptide, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide" CG18417 16-Dec-15 2015_12 "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0044862 MMS-6 MMS-6 http://flybase.net/reports/FBgn0044862.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0024235 fs(1)513 fs(1)513 http://flybase.net/reports/FBgn0024235.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "egg chamber,stage S7 oocyte,nurse cell" FBgn0053461 CG33461 http://flybase.net/reports/FBgn0053461.html "FBgn0034038, FBgn0050086" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP41, CG30086, CG8215" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG33461 16-Dec-15 2015_12 WBGene00006621(try-3) DRSC22892 K -0.963308304 0.695166571 0.025626953 -0.551202839 0.922651279 1.784772587 FBgn0022746 anon-H2 anon-H2 http://flybase.net/reports/FBgn0022746.html gene H2 16-Dec-15 2015_12 FBgn0002130 l(2)K203 lethal (2) K203 http://flybase.net/reports/FBgn0002130.html gene 16-Dec-15 2015_12 lethal FBgn0052693 Gr9a Gustatory receptor 9a http://flybase.net/reports/FBgn0052693.html protein_coding_gene 0008527=taste receptor activity 0050912=detection of chemical stimulus involved in sensory perception of taste 0016021=integral component of membrane "CG32693, GR9a, Gr9a" IPR013604=7TM chemoreceptor CG32693 16-Dec-15 2015_12 viable FBgn0053280 CG33280 http://flybase.net/reports/FBgn0053280.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040703 CG12494 http://flybase.net/reports/FBgn0040703.html protein_coding_gene 16-Dec-15 2015_12 FBgn0015540 scs' special chromatin structure' http://flybase.net/reports/FBgn0015540.html insulator SCS' 16-Dec-15 2015_12 FBgn0052944 CG32944 http://flybase.net/reports/FBgn0052944.html "FBgn0037246, FBgn0037247" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0008360=regulation of cell shape, 0007015=actin filament organization" "CG9818, CG10532" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG32944 16-Dec-15 2015_12 WBGene00010838(M03C11.1) ENSXETG00000012715(STK32A) "ENSMUSG00000029123(Stk32b),ENSMUSG00000015981(Stk32c),ENSMUSG00000039954(Stk32a)" "ENSG00000152953(STK32B),ENSG00000165752(STK32C),ENSG00000169302(STK32A)" "viable,fertile" DRSC12341 E -0.275653851 -0.608386977 -1.804873754 0.080624562 -0.012839207 0.003319323 FBgn0011203 boc bocce http://flybase.net/reports/FBgn0011203.html gene 0007285=primary spermatocyte growth "ms(2)boc, ms(2)02530" 16-Dec-15 2015_12 "male sterile,recessive,female semi-sterile" "testis,primary spermatocyte cyst" FBgn0032483 CG15482 http://flybase.net/reports/FBgn0032483.html protein_coding_gene CG15482 16-Dec-15 2015_12 viable FBgn0043060 Tl::Tollo Tl::Tollo http://flybase.net/reports/FBgn0043060.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0033337 CG8272 http://flybase.net/reports/FBgn0033337.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "FBXL9, CT8327" "IPR001810=F-box domain, IPR026940=SCF E3 ubiquitin ligase complex F-box protein GrrA/Grr1, IPR006553=Leucine-rich repeat, cysteine-containing subtype" CG8272 16-Dec-15 2015_12 ENSMUSG00000041679(Lrrc29) ENSG00000118564(FBXL5) viable FBgn0042642 fof failure to fuse http://flybase.net/reports/FBgn0042642.html gene 16-Dec-15 2015_12 FBgn0028429 I-2 Inhibitor-2 http://flybase.net/reports/FBgn0028429.html protein_coding_gene "0008157=protein phosphatase 1 binding, 0004864=protein phosphatase inhibitor activity" "0043666=regulation of phosphoprotein phosphatase activity, 0035308=negative regulation of protein dephosphorylation, 0009966=regulation of signal transduction" 0000164=protein phosphatase type 1 complex "phosphatase inhibitor-2, I-2PP1, Dm I-2, I-2Dm, SET, inhibitor-2, DI-2, CG10574" IPR007062=Protein phosphatase inhibitor 2 (IPP-2) CG10574 16-Dec-15 2015_12 WBGene00021312(Y32H12A.4) "ENSMUSG00000047714(Ppp1r2),ENSMUSG00000052025(1700023I07Rik),ENSMUSG00000045217(4930403L05Rik)" "ENSG00000184203(PPP1R2),ENSG00000215471" " embryonic stage | 0-24 hr , adult stage , pupal stage , adult stage | male , larval stage , embryonic stage | early , spermatogenesis && adult stage , embryonic stage , adult stage | female " " adult head

, larval brain

, imaginal disc

, spermatocyte

" viable DRSC11194 IE -0.805357948 -2.044235907 -4.00460864 -2.869504569 1.178547913 -0.286681012 FBgn0025441 Dhc1 Dynein heavy chain 1 http://flybase.net/reports/FBgn0025441.html gene 0003774=motor activity "0007018=microtubule-based movement, 0016482=cytoplasmic transport" 0005875=microtubule associated complex "Dhc, dhc, DHC, dynein, DmDhc1, Dynein heavy chain" 16-Dec-15 2015_12 FBgn0066076 Stalker4\ORF2 ORF2 http://flybase.net/reports/FBgn0066076.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration ORF2 "IPR015416=Zinc finger, H2C2-type, histone UAS binding, IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0014999 tmo tammo http://flybase.net/reports/FBgn0014999.html gene 16-Dec-15 2015_12 macrochaeta FBgn0003342 sct scooped thickvein http://flybase.net/reports/FBgn0003342.html gene 16-Dec-15 2015_12 "partially lethal - majority live,male sterile,eye color defective" "wing,wing vein,eye,tergite" FBgn0261598 M(2)31E Minute (2) 31E http://flybase.net/reports/FBgn0261598.html gene 16-Dec-15 2015_12 FBgn0028028 l(3)S103114 lethal (3) S103114 http://flybase.net/reports/FBgn0028028.html gene 1031/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0266359 CR45007 http://flybase.net/reports/FBgn0266359.html non_protein_coding_gene CR45007 16-Dec-15 2015_12 FBgn0267809 CR46134 http://flybase.net/reports/FBgn0267809.html non_protein_coding_gene CR46134 16-Dec-15 2015_12 FBgn0266412 CR45052 http://flybase.net/reports/FBgn0266412.html non_protein_coding_gene CR45052 16-Dec-15 2015_12 FBgn0001877 l(1)YA13 lethal (1) YA13 http://flybase.net/reports/FBgn0001877.html gene 16-Dec-15 2015_12 lethal FBgn0267160 CR45600 http://flybase.net/reports/FBgn0267160.html non_protein_coding_gene CR45600 16-Dec-15 2015_12 FBgn0015453 l(1)HM32 lethal (1) HM32 http://flybase.net/reports/FBgn0015453.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0021968 l(2)k10012 lethal (2) k10012 http://flybase.net/reports/FBgn0021968.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0046878 Obp83cd Odorant-binding protein 83cd http://flybase.net/reports/FBgn0046878.html "FBgn0037400, FBgn0046877" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "83c, Odorant-binding protein 83d, 83d, CG15582, 83c-1, 83c-2, Obp83c, DmelObp83cd, Obp83d, odorant receptor 83cd, Odorant-binding protein 83c" IPR006170=Pheromone/general odorant binding protein CG15582 16-Dec-15 2015_12 viable FBgn0259215 Ir93a Ionotropic receptor 93a http://flybase.net/reports/FBgn0259215.html "FBgn0038835, FBgn0038836" protein_coding_gene "0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" 0050907=detection of chemical stimulus involved in sensory perception "0016021=integral component of membrane, 0016020=membrane" "CT35907, CG17275, ionotropic receptor 93a, ir93a, CG42315, CG17274, DmelIR93a, IR93a" IPR001320=Ionotropic glutamate receptor CG42315 16-Dec-15 2015_12 viable FBgn0083153 S(smoDN)189 Suppressor of smoDN 189 http://flybase.net/reports/FBgn0083153.html gene 16-Dec-15 2015_12 FBgn0034075 Asph Aspartyl ë_-hydroxylase http://flybase.net/reports/FBgn0034075.html FBgn0034074 protein_coding_gene 0004597=peptide-aspartate beta-dioxygenase activity 0018193=peptidyl-amino acid modification 0012505=endomembrane system "BAH/humbug, CG18658, CG8421, Aspartyl beta-hydroxylase" "IPR011990=Tetratricopeptide-like helical domain, IPR007803=Aspartyl/asparaginy/proline hydroxylase, IPR027443=Isopenicillin N synthase-like, IPR013026=Tetratricopeptide repeat-containing domain" CG8421 16-Dec-15 2015_12 WBGene00010703(K09A9.6) ENSMUSG00000028207(Asph) ENSG00000198363(ASPH) "viable,fertile" FBgn0085637 CG41374 http://flybase.net/reports/FBgn0085637.html FBan0041374 protein_coding_gene 16-Dec-15 2015_12 FBgn0053629 CR33629 http://flybase.net/reports/FBgn0053629.html FBpp0090978 pseudogene_attribute CG33629 CR33629 16-Dec-15 2015_12 FBgn0004660 l(2)41Ae lethal (2) 41Ae http://flybase.net/reports/FBgn0004660.html "FBgn0002065, FBgn0002166, FBgn0002169, FBgn0020393" gene "l(2)C147, l(2R)A', 41Ae, Nipped, l(2R)34-2, l(2)EMS34-14, l(2)C124, GroupIV, l(2)Sp9b" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267256 CR45692 http://flybase.net/reports/FBgn0267256.html non_protein_coding_gene CR45692 16-Dec-15 2015_12 FBgn0031163 CG14579 http://flybase.net/reports/FBgn0031163.html protein_coding_gene CG14579 16-Dec-15 2015_12 FBgn0035788 CG8541 http://flybase.net/reports/FBgn0035788.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle IPR022727=Pupal cuticle protein C1 CG8541 16-Dec-15 2015_12 viable FBgn0069305 X-75-9 X-75-9 http://flybase.net/reports/FBgn0069305.html gene 0007399=nervous system development 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,neurogenic phenotype,recessive,some die during embryonic stage" FBgn0259870 Su(Ste):CR42439 Su(Ste):CR42439 http://flybase.net/reports/FBgn0259870.html non_protein_coding_gene CR42439 CR42439 16-Dec-15 2015_12 FBgn0261674 CG42709 http://flybase.net/reports/FBgn0261674.html "FBgn0036312, FBgn0043348, FBgn0261626" protein_coding_gene "CG17667, EP(3)3622, EP3622" "IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat, IPR026906=Leucine rich repeat 5" CG42709 16-Dec-15 2015_12 ENSXETG00000014980() ENSMUSG00000049612(Omg) FBgn0001142 Gs1 Glutamine synthetase 1 http://flybase.net/reports/FBgn0001142.html FBgn0003695 protein_coding_gene "0015930=glutamate synthase activity, 0004356=glutamate-ammonia ligase activity" "0006909=phagocytosis, 0006542=glutamine biosynthetic process, 0006541=glutamine metabolic process, 0007005=mitochondrion organization" "0005811=lipid particle, 0005739=mitochondrion" "l(2)21Bc, Glutamate-ammonia ligase, glutamine synthetase-1, Glutamine synthetase, GLUTAMINE SYNTHETASE 1, fs(2)throng, gsI, glutamine synthetase 1, CG2718, mt-gs, throng, fs(2)P52, GSI, GsI, thg, gs-m, GS1, glutamine synthase 1, glutamine synthetase I, mitochondrial glutamine synthetase" "IPR027302=Glutamine synthetase, N-terminal conserved site, IPR008146=Glutamine synthetase, catalytic domain, IPR008147=Glutamine synthetase, beta-Grasp domain, IPR027303=Glutamine synthetase, glycine-rich site, IPR014746=Glutamine synthetase/guanido kinase, catalytic domain" CG2718 16-Dec-15 2015_12 YPR035W(GLN1) " pupal stage | late , larval stage | second instar , embryonic stage , larval stage | first instar " "chemical sensitive,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,female sterile,non-rescuable maternal effect,lethal,wild-type,electrophoretic variant,slow,fast,immune response defective,viable" "A1-7 dorsal oblique muscle 2,embryonic somatic muscle,muscle attachment site" FBgn0004374 neb nebbish http://flybase.net/reports/FBgn0004374.html "FBgn0010543, FBgn0015262, FBgn0019965, FBgn0022079" protein_coding_gene "0008574=ATP-dependent microtubule motor activity, plus-end-directed, 0005524=ATP binding, 0003682=chromatin binding, 0008017=microtubule binding, 0008157=protein phosphatase 1 binding, 0003777=microtubule motor activity" "0007076=mitotic chromosome condensation, 0007018=microtubule-based movement, 0030707=ovarian follicle cell development, 0007126=meiotic nuclear division, 0051726=regulation of cell cycle, 0000070=mitotic sister chromatid segregation, 0045448=mitotic cell cycle, embryonic, 0007059=chromosome segregation, 0048477=oogenesis" "0000792=heterochromatin, 0005871=kinesin complex" "l(2)k00802, l(2)k07614, klp38B, sl(2)ry3, DmKlp38B, Mot, KIF 14, CG10718, Dm0332, Klp38, Neb, KLP38B, KLP 38B, 38B.12, nebb, l(2)03552, tio, Klp38B, Nebbish, Kinesin-like protein at 38B, DmNeb, Mothra, KLP-38B, tiovivo, KIF14, sl(2)ry, 38B.10" "IPR008984=SMAD/FHA domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR000253=Forkhead-associated (FHA) domain, IPR001752=Kinesin motor domain, IPR027640=Kinesin-like protein" CG10718 16-Dec-15 2015_12 ENSXETG00000011461() ENSMUSG00000041498(Kif14) ENSG00000118193(KIF14) " adult stage && oogenesis stage , embryonic stage | mid , spermatogenesis && adult stage , embryonic stage && adult stage , adult stage , larval stage | third instar , larval stage , embryonic stage , embryonic stage | early " " ovary

, procephalic neuroblast

, testis

, spermatocyte

, primary gonial cell

, imaginal disc

, larval brain | restricted

, imaginal disc | restricted

, nurse cell

, ventral nerve cord

, follicle cell

" "mitotic cell cycle defective,lethal,recessive,female sterile,male sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during immature adult stage,behavior defective,partially lethal - majority die,some die during larval stage,viable,maternal effect,partially,rescuable maternal effect,wild-type,germline clone" "nuclear chromosome,centrosome,eye,macrochaeta,external sensory organ,multidendritic neuron,chordotonal organ,lateral,neuron,interommatidial bristle,wing,egg,maternal effect,embryo,syncytial blastoderm embryo,pole cell,nucleus | blastoderm stage | maternal effect,spindle | embryonic stage | maternal effect,chromatin | embryonic stage | maternal effect,ommatidium,adult abdominal sensillum,spermatozoon,egg chamber,ovary,follicle cell,adult neuroblast & mitosis & nuclear chromosome,adult neuroblast & spindle,humeral bristle,adult abdomen,embryonic/larval brain,embryonic epidermis,germline clone,embryonic/first instar larval cuticle,embryonic abdominal segment,embryonic head,embryonic abdomen" FBgn0259630 B2034 http://flybase.net/reports/FBgn0259630.html gene 16-Dec-15 2015_12 visible "tarsal segment,unguis,wing,eye" FBgn0066096 MSu1 MSu1 http://flybase.net/reports/FBgn0066096.html gene 16-Dec-15 2015_12 FBgn0005617 msl-1 male-specific lethal 1 http://flybase.net/reports/FBgn0005617.html "FBgn0001318, FBgn0002851" protein_coding_gene "0046983=protein dimerization activity, 0003677=DNA binding, 0003682=chromatin binding, 0005515=protein binding, 0044212=transcription regulatory region DNA binding, 0031625=ubiquitin protein ligase binding" "0009047=dosage compensation by hyperactivation of X chromosome, 0043984=histone H4-K16 acetylation, 0031936=negative regulation of chromatin silencing, 0016457=dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome, 0007549=dosage compensation" "0005694=chromosome, 0005634=nucleus, 0016456=X chromosome located dosage compensation complex, transcription activating, 0000805=X chromosome, 0046536=dosage compensation complex, 0072487=MSL complex, 0000228=nuclear chromosome" "Msl 1-3, km(2)B, CG10385, male specifc lethal, MSL, Msl-1, male specific lethal 1, i94, Msl1, MSL1, killer-of-males-B, msl, msl1, MSL-1, kmB, mls-1, MSL3" "IPR026711=Protein male-specific lethal-1, IPR029332=PEHE domain" CG10385 16-Dec-15 2015_12 ENSMUSG00000052915(Msl1) " embryonic stage -- adult stage , adult stage | female , adult stage | male " " adult stage | male , larval stage | male , larval stage | female , embryonic stage " "viable,fertile,lethal,male limited,heat sensitive,male,female,recessive,wild-type,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,partially,short lived,visible" "trichogen cell,mesothoracic tergum" FBgn0261866 ltr loiterer http://flybase.net/reports/FBgn0261866.html gene 0035177=larval foraging behavior 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065341 l(2)SH1834 lethal (2) SH1834 http://flybase.net/reports/FBgn0065341.html gene l(2)SH2 1834 16-Dec-15 2015_12 "lethal,recessive" FBgn0014990 l(2)46Df lethal (2) 46Df http://flybase.net/reports/FBgn0014990.html gene "XII, Group XII" 16-Dec-15 2015_12 lethal FBgn0265416 Neto Neuropilin and tolloid-like http://flybase.net/reports/FBgn0265416.html "FBgn0052635, FBgn0030488, FBgn0030489, FBgn0030490, FBgn0030491" protein_coding_gene "0043113=receptor clustering, 0035187=hatching behavior, 0097106=postsynaptic density organization, 0030510=regulation of BMP signaling pathway, 0046331=lateral inhibition, 0050808=synapse organization, 0060361=flight, 0007528=neuromuscular junction development, 0097688=glutamate receptor clustering, 0051726=regulation of cell cycle, 0040011=locomotion, 0007274=neuromuscular synaptic transmission, 0001941=postsynaptic membrane organization" "0008328=ionotropic glutamate receptor complex, 0097482=muscle cell postsynaptic density, 0031594=neuromuscular junction" "CG15753, CG32635, net, CG15752, CG15751, CG44328, neuropilin and tolloid-like, neto, CG12727, CT36003, tld-like" "IPR000859=CUB domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat" CG44328 16-Dec-15 2015_12 DRSC19503 K 0.150061825 0.125724018 0.910320035 0.018075519 -1.657726525 -0.803162426 FBgn0029906 xit xiantuan http://flybase.net/reports/FBgn0029906.html protein_coding_gene "0042283=dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity" "0006486=protein glycosylation, 0003384=apical constriction involved in gastrulation, 0007377=germ-band extension, 0006490=oligosaccharide-lipid intermediate biosynthetic process, 0006487=protein N-linked glycosylation" "0005783=endoplasmic reticulum, 0005789=endoplasmic reticulum membrane" "CG4542, Dalg8, dAlg8" "IPR004856=Glycosyl transferase, ALG6/ALG8" CG4542 16-Dec-15 2015_12 ENSDARG00000044627(alg8) YOR067C(ALG8) WBGene00007464(C08H9.3) ENSXETG00000010450(ALG8) ENSMUSG00000035704(Alg8) ENSG00000159063(ALG8) viable "cephalic furrow,germline clone,ventral furrow" FBgn0052113 CG32113 http://flybase.net/reports/FBgn0052113.html "FBgn0036307, FBgn0036308" protein_coding_gene 0016192=vesicle-mediated transport 0005875=microtubule associated complex "CG11003, CG11002" "IPR000772=Ricin B, lectin domain, IPR026847=Vacuolar protein sorting-associated protein 13, IPR026854=Vacuolar protein sorting-associated protein 13A, N-terminal domain, IPR009543=Vacuolar protein sorting-associated protein 13, SHR-binding domain" CG32113 16-Dec-15 2015_12 ENSDARG00000017986(vps13d) WBGene00016117(C25H3.8) ENSXETG00000001391(VPS13D) ENSMUSG00000020220(Vps13d) ENSG00000048707(VPS13D) "viable,visible" trichogen cell FBgn0267075 CR45519 http://flybase.net/reports/FBgn0267075.html non_protein_coding_gene CR45519 16-Dec-15 2015_12 FBgn0043043 Desat2 Desaturase 2 http://flybase.net/reports/FBgn0043043.html "FBgn0017619, FBgn0026613, FBgn0038050" protein_coding_gene "0004768=stearoyl-CoA 9-desaturase activity, 0016717=oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water" "0006633=fatty acid biosynthetic process, 0055114=oxidation-reduction process, 0006723=cuticle hydrocarbon biosynthetic process, 0006629=lipid metabolic process" "desat, desaturase-2, Desat2, ds2, Desaturase2, desaturase2, desat2/Fad, desaturase, Fatty acid desaturase, 7-11HD, desat-2, desat2, Fad, 7,11-heptacosadiene modifier, CG5925" "IPR015876=Fatty acid desaturase, type 1, core, IPR005804=Fatty acid desaturase domain" CG5925 16-Dec-15 2015_12 "ENSDARG00000033662(scd),ENSDARG00000030265(scdb)" YGL055W(OLE1) "WBGene00001398(fat-6),WBGene00001399(fat-7),WBGene00001397(fat-5)" ENSXETG00000023757(BC096632.1) "ENSMUSG00000037071(Scd1),ENSMUSG00000025203(Scd2),ENSMUSG00000025202(Scd3),ENSMUSG00000050195(Scd4)" "ENSG00000099194(SCD),ENSG00000145284(SCD5)" FBgn0034390 CG15093 http://flybase.net/reports/FBgn0034390.html protein_coding_gene "0008442=3-hydroxyisobutyrate dehydrogenase activity, 0004616=phosphogluconate dehydrogenase (decarboxylating) activity, 0051287=NAD binding" "0006520=cellular amino acid metabolic process, 0055114=oxidation-reduction process" "0005739=mitochondrion, 0005811=lipid particle" "CG 15093, 3-hydroxyisobutyrate dehydrogenase, CT34968" "IPR029154=3-hydroxyisobutyrate dehydrogenase, NAD-binding domain, IPR002204=3-hydroxyisobutyrate dehydrogenase-related, conserved site, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011548=3-hydroxyisobutyrate dehydrogenase, IPR006115=6-phosphogluconate dehydrogenase, NADP-binding, IPR015815=3-hydroxyisobutyrate dehydrogenase-related, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR016040=NAD(P)-binding domain" CG15093 16-Dec-15 2015_12 "ENSDARG00000007959(hibadhb),ENSDARG00000036236(hibadha)" WBGene00007122(B0250.5) ENSXETG00000000750(Q5BKJ0_XENTR) ENSMUSG00000029776(Hibadh) ENSG00000106049(HIBADH) "viable,fertile" FBgn0053673 CG33673 http://flybase.net/reports/FBgn0053673.html protein_coding_gene IPR006214=Bax inhibitor 1-related CG33673 16-Dec-15 2015_12 YNL305C() FBgn0263472 snoRNA:2R:9445205 http://flybase.net/reports/FBgn0263472.html snoRNA_gene "snoRNA:2R_9445205, chr2R:9073472..9073780" CR43587 16-Dec-15 2015_12 FBgn0002965 npr3 non-pupariating 3 http://flybase.net/reports/FBgn0002965.html FBgn0001608 gene "l(1)npr-3, discs degenerate 12, l(1)dd12, l(1)d.deg.-12, l(1)d.deg.12, l(1)d deg-12" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0259440 EP-435 http://flybase.net/reports/FBgn0259440.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0010040 GstD4 Glutathione S transferase D4 http://flybase.net/reports/FBgn0010040.html FBgn0038023 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "DmGstd4, GstD23, gstD23, DmGSTD4, gstd4, DmGST23, GSTD4, GST, Gst, Glutathione-S-transferase, Glutathione S transferase D23, CG11512" "IPR004046=Glutathione S-transferase, C-terminal, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG11512 16-Dec-15 2015_12 YNL229C(URE2) adult stage viable FBgn0259370 EP-1152.2 http://flybase.net/reports/FBgn0259370.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0013348 TpnC41C Troponin C at 41C http://flybase.net/reports/FBgn0013348.html "FBan0041446, FBgn0084010" protein_coding_gene 0005509=calcium ion binding "TPNC, unnamed, TpnCIIIa, DmTpnCIIIa, TnC, troponin-C, TpnC41, DmTnC1, TroponinC at 41C, TpnC IIIa, TnC41C, DmTpnC41C, TNC41C, CG2981, troponin C, TnC1" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG2981 16-Dec-15 2015_12 WBGene00006583(tnc-2) " pupal stage | mid , adult stage , pupal stage--adult stage , pupal stage | late " organism

adult stage " leg

, indirect flight muscle

" FBgn0264528 ff25 http://flybase.net/reports/FBgn0264528.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" FBgn0065975 iab4-5.s iab4-5.s http://flybase.net/reports/FBgn0065975.html gene 4-5 s 16-Dec-15 2015_12 FBgn0034496 CG9143 http://flybase.net/reports/FBgn0034496.html protein_coding_gene "0003729=mRNA binding, 0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding" cg9143 "IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif" CG9143 16-Dec-15 2015_12 YBR142W(MAK5) WBGene00018890(F55F8.2) ENSXETG00000010314(DDX24) ENSMUSG00000041645(Ddx24) ENSG00000089737(DDX24) "viable,fertile" FBgn0065168 l(3)SH031 lethal (3) SH031 http://flybase.net/reports/FBgn0065168.html gene l(2)SH3 031 16-Dec-15 2015_12 "lethal,recessive" FBgn0016003 l(3)61Da lethal (3) 61Da http://flybase.net/reports/FBgn0016003.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031493 CG3605 http://flybase.net/reports/FBgn0031493.html protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0005686=U2 snRNP, 0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "IPR006568=PSP, proline-rich, IPR007180=Domain of unknown function DUF382" CG3605 16-Dec-15 2015_12 ENSDARG00000018049(zgc:136773) YMR240C(CUS1) WBGene00021004(W03F9.10) ENSXETG00000008422(SF3B2) ENSMUSG00000024853(Sf3b2) ENSG00000087365(SF3B2) lethal DRSC00619 EK -0.44974458 1.428024303 -2.493881031 -1.830599245 -1.666780762 -1.307860185 FBgn0034821 CG9876 http://flybase.net/reports/FBgn0034821.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG9876 16-Dec-15 2015_12 "viable,fertile" DRSC04586 I 1.769620343 0.214193936 1.027371655 -0.075117282 -0.30382595 -1.063932979 FBgn0265543 CR44393 http://flybase.net/reports/FBgn0265543.html non_protein_coding_gene lincRNA.164 CR44393 16-Dec-15 2015_12 FBgn0013537 l(2)ry41 lethal (2) ry41 http://flybase.net/reports/FBgn0013537.html gene "unnamed, l(2)41" 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0030700 CG15914 http://flybase.net/reports/FBgn0030700.html protein_coding_gene 0009058=biosynthetic process PIG "IPR022701=Glycosyltransferase family 1, N-terminal, IPR001296=Glycosyl transferase, family 1" CG15914 16-Dec-15 2015_12 ENSDARG00000020642(gtdc1) ENSXETG00000000254(gtdc1) ENSMUSG00000036890(Gtdc1) ENSG00000121964(GTDC1) viable FBgn0259552 GG01228 http://flybase.net/reports/FBgn0259552.html gene 16-Dec-15 2015_12 visible wing FBgn0040011 Slmap Sarcolemma associated protein http://flybase.net/reports/FBgn0040011.html FBan0017494 protein_coding_gene "0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction" "sarcolemma associated protein, Sarcolemma associated protein ortholog, CG17494" "IPR000253=Forkhead-associated (FHA) domain, IPR008984=SMAD/FHA domain" CG17494 16-Dec-15 2015_12 ENSDARG00000054458(zgc:153887) "YDR200C(VPS64),YLR238W(FAR10)" WBGene00007227(C01G6.5) ENSXETG00000008658(SLMAP) ENSMUSG00000021870(Slmap) ENSG00000163681(SLMAP) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0066088 RH13 RNA Helicase 13 http://flybase.net/reports/FBgn0066088.html gene DmRH13 16-Dec-15 2015_12 FBgn0085555 CG41018 http://flybase.net/reports/FBgn0085555.html FBan0041018 protein_coding_gene 16-Dec-15 2015_12 FBgn0259471 EP-241 http://flybase.net/reports/FBgn0259471.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0263850 CG43711 http://flybase.net/reports/FBgn0263850.html protein_coding_gene CG43711 16-Dec-15 2015_12 FBgn0039867 CstF-50 CstF-50 http://flybase.net/reports/FBgn0039867.html protein_coding_gene 0006379=mRNA cleavage "0005654=nucleoplasm, 0005848=mRNA cleavage stimulating factor complex" "CstF50, CG2261" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG2261 16-Dec-15 2015_12 ENSDARG00000044820(zgc:77560) WBGene00000773(cpf-1) ENSXETG00000012030(cstf1) ENSMUSG00000027498(Cstf1) ENSG00000101138(CSTF1) viable DRSC15434 I 2.516826499 2.220094545 0.882436123 0.258475278 -0.027015959 -0.090801024 FBgn0004115 Su(var)311 Suppressor of variegation 311 http://flybase.net/reports/FBgn0004115.html gene 16-Dec-15 2015_12 FBgn0265950 CR44737 http://flybase.net/reports/FBgn0265950.html non_protein_coding_gene "lincRNA.189, lincRNA.188" CR44737 16-Dec-15 2015_12 FBgn0267488 Mcr Macroglobulin complement-related http://flybase.net/reports/FBgn0267488.html "FBgn0087010, FBgn0041178, FBgn0031984, FBgn0014086, FBgn0020240, FBgn0264800, FBgn0069452" protein_coding_gene "0005515=protein binding, 0004866=endopeptidase inhibitor activity, 0005198=structural molecule activity" "0019991=septate junction assembly, 0006910=phagocytosis, recognition, 0035159=regulation of tube length, open tracheal system, 0008258=head involution, 0050832=defense response to fungus, 0007391=dorsal closure, 0019731=antibacterial humoral response, 0046331=lateral inhibition" "0005886=plasma membrane, 0005615=extracellular space, 0016324=apical plasma membrane, 0016327=apicolateral plasma membrane, 0016323=basolateral plasma membrane, 0005918=septate junction, 0016021=integral component of membrane, 0016328=lateral plasma membrane" "TepVI, Enhancer of broad, CG7586, Thiolester containing protein VI, luftschlange, DmTEP6, Enhancer of broad 155, mcr, Tep6, alpha-2-Mrp, TEP6, anon-28DE, alpha-2-macroglobulin related, dTEPVI, E(br)155, TEP, Macroglobulin complement related, luf, TEP6mel" "IPR001599=Alpha-2-macroglobulin, IPR011625=Alpha-2-macroglobulin, N-terminal 2, IPR002890=Alpha-2-macroglobulin, N-terminal, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR009048=Alpha-macroglobulin, receptor-binding, IPR011626=Alpha-macroglobulin complement component, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG7586 16-Dec-15 2015_12 " spermatogenesis && adult stage , embryonic stage " " spermatocyte

, testis

, embryonic peripheral nervous system

" FBgn0259938 cwo clockwork orange http://flybase.net/reports/FBgn0259938.html "FBgn0259894, FBgn0016941, FBgn0011718, FBgn0037813" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity, 0003677=DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0042752=regulation of circadian rhythm, 0032922=circadian regulation of gene expression" 0005634=nucleus "mel_cwo, CLOCKWORK ORANGE, GM05287, Stich, AAF24476.1, bHLHe49, CG17100, Cwo, clockworkorange, unnamed, CWO" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG17100 16-Dec-15 2015_12 "ENSMUSG00000030256(Bhlhe41),ENSMUSG00000030103(Bhlhe40)" "ENSG00000123095(BHLHE41),ENSG00000134107(BHLHE40)" DRSC17072 E 1.004402566 -0.720398823 0.656748718 -2.280856114 0.498138928 -0.226399457 FBgn0011894 tRNA:K2:42Ec transfer RNA:lys2:42Ec http://flybase.net/reports/FBgn0011894.html "FBgn0003796, FBgn0011886, FBgn0050302, FBgn0060182" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033444=AAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30302, tRNAlys, AE002778.trna2-LysCTT, tRNA:K:CTT:AE002778-b, tRNA:K2, tRNA[Lys][[2]], tRNA:lys2:42Ec, chr2R.trna89-LysCTT" CR30302 16-Dec-15 2015_12 FBgn0037888 scpr-B SCP-containing protein B http://flybase.net/reports/FBgn0037888.html FBgn0044768 protein_coding_gene 0005576=extracellular region "cg17210, SCP-Related-B, SCPR-B, anon-WO0140519.115, scp-B, CG17210" "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG17210 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" "viable,fertile" FBgn0014241 l(2)32Ab lethal (2) 32Ab http://flybase.net/reports/FBgn0014241.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034612 CG10505 http://flybase.net/reports/FBgn0034612.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" "0010043=response to zinc ion, 0055085=transmembrane transport, 0046688=response to copper ion" 0043190=ATP-binding cassette (ABC) transporter complex "ABC transporter, Dme_CG10505" "IPR011527=ABC transporter type 1, transmembrane domain, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain" CG10505 16-Dec-15 2015_12 viable FBgn0052704 Ir8a Ionotropic receptor 8a http://flybase.net/reports/FBgn0052704.html "FBgn0030110, FBgn0030111" protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0005230=extracellular ligand-gated ion channel activity, 0015026=coreceptor activity, 0015276=ligand-gated ion channel activity, 0005102=receptor binding, 0004984=olfactory receptor activity, 0005234=extracellular-glutamate-gated ion channel activity, 0036082=extracellular phenylacetaldehyde-gated ion channel activity" "0010157=response to chlorate, 0050907=detection of chemical stimulus involved in sensory perception, 0019226=transmission of nerve impulse, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0010034=response to acetate, 0006811=ion transport, 0042048=olfactory behavior, 0050850=positive regulation of calcium-mediated signaling, 0071311=cellular response to acetate" "0043235=receptor complex, 0005887=integral component of plasma membrane, 0005886=plasma membrane, 0071683=sensory dendrite, 0016021=integral component of membrane, 0032590=dendrite membrane" "CG32704, DmelIR8a, IR8a, CG12666, CT7438, CG12122, ionotropic receptor 8a" "IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor, IPR001508=Ionotropic glutamate receptor, metazoa, IPR030407=Ionotropic receptor 8a-related" CG32704 16-Dec-15 2015_12 "smell perception defective,viable,fertile,neurophysiology defective" sensillum coeloconicum of antennal segment 3 FBgn0065442 l(2)SH1454 lethal (2) SH1454 http://flybase.net/reports/FBgn0065442.html gene l(2)SH2 1454 16-Dec-15 2015_12 "lethal,recessive" FBgn0033507 CG12909 http://flybase.net/reports/FBgn0033507.html protein_coding_gene 0005730=nucleolus "IPR014898=Zinc finger, C2H2, LYAR-type" CG12909 16-Dec-15 2015_12 ENSDARG00000032505(zgc:65749) WBGene00007628(C16C10.8) ENSXETG00000016038(LYAR) ENSMUSG00000067367(Lyar) ENSG00000145220(LYAR) viable FBgn0043988 Su(rst)E156 Su(rst)E156 http://flybase.net/reports/FBgn0043988.html gene 0001745=compound eye morphogenesis E156 16-Dec-15 2015_12 viable FBgn0052483 CG32483 http://flybase.net/reports/FBgn0052483.html protein_coding_gene 0004185=serine-type carboxypeptidase activity 0006508=proteolysis "IPR001563=Peptidase S10, serine carboxypeptidase, IPR029058=Alpha/Beta hydrolase fold" CG32483 16-Dec-15 2015_12 ENSDARG00000040072(scpep1) YGL203C(KEX1) WBGene00012530(Y32F6A.5) ENSXETG00000020061(SCPEP1) ENSMUSG00000000278(Scpep1) ENSG00000121064(SCPEP1) viable FBgn0002099 l(2)57Ce lethal (2) 57Ce http://flybase.net/reports/FBgn0002099.html gene l(2)57CDa 16-Dec-15 2015_12 lethal FBgn0030410 Aven Aven ortholog http://flybase.net/reports/FBgn0030410.html protein_coding_gene 0010972=negative regulation of G2/M transition of mitotic cell cycle "0005829=cytosol, 0005634=nucleus" "CG15727, dAven" CG15727 16-Dec-15 2015_12 "decreased cell size,mitotic cell cycle defective,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,lethal,temperature conditional,viable" "ovary,adult fat body" FBgn0045849 l(4)102Fd lethal (4) 102Fd http://flybase.net/reports/FBgn0045849.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032886 CG9328 http://flybase.net/reports/FBgn0032886.html "FBgn0026591, FBgn0046994" protein_coding_gene "BEST:LD01639, BcDNA:SD01241, LD01639, 38E.22" IPR009533=Protein of unknown function DUF1151 CG9328 16-Dec-15 2015_12 "ENSDARG00000023782,ENSDARG00000026865(fam107b),ENSDARG00000059399" "ENSXETG00000009120(BC080351.1),ENSXETG00000008652(FAM107A)" "ENSMUSG00000026655(Fam107b),ENSMUSG00000021750(Fam107a)" viable FBgn0062253 Su(dpp)YE10 Su(dpp)YE10 http://flybase.net/reports/FBgn0062253.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,amnioserosa,abdominal 4 ventral denticle belt" FBgn0029766 CG15784 http://flybase.net/reports/FBgn0029766.html protein_coding_gene CG15784 16-Dec-15 2015_12 "viable,fertile,lethal,recessive,partially lethal - majority die,visible" mesothoracic tergum FBgn0032048 Dh31 Diuretic hormone 31 http://flybase.net/reports/FBgn0032048.html "FBgn0027765, FBgn0066015" protein_coding_gene "0008613=diuretic hormone activity, 0001664=G-protein coupled receptor binding, 0005184=neuropeptide hormone activity" "0007186=G-protein coupled receptor signaling pathway, 0007589=body fluid secretion, 0007218=neuropeptide signaling pathway, 0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0010841=positive regulation of circadian sleep/wake cycle, wakefulness" 0005615=extracellular space "DH[[31]], diuretic Hormone 31, DH 31, Calcitonin, anon-EST:Posey114, Calcitonin-like diuretic hormone (31 residues), CG13094, Diuretic Hormone 31, Dh[[31]], DH-II, diuretic hormone 31, dh31, Drm-DH[[31]], DH[[31], diuretic hormone, anon-WO02059370.45, DH31, Drome-DH[[31]], drome-DH31" CG13094 16-Dec-15 2015_12 "viable,fertile" FBgn0016768 l(1)1Bl lethal (1) 1Bl http://flybase.net/reports/FBgn0016768.html gene "unnamed, anon-1Bd" 16-Dec-15 2015_12 "lethal,recessive" FBgn0065395 l(2)SH1616 lethal (2) SH1616 http://flybase.net/reports/FBgn0065395.html gene l(2)SH2 1616 16-Dec-15 2015_12 "lethal,recessive" FBgn0035120 wac wee Augmin http://flybase.net/reports/FBgn0035120.html protein_coding_gene "0005515=protein binding, 0008017=microtubule binding" "0007052=mitotic spindle organization, 0051225=spindle assembly, 0007143=female meiotic division, 0007056=spindle assembly involved in female meiosis, 0031122=cytoplasmic microtubule organization, 0051301=cell division" "0043234=protein complex, 0072687=meiotic spindle, 0070652=HAUS complex, 0005819=spindle, 0005875=microtubule associated complex" "CG13879, Augmin, Wac, was" CG13879 16-Dec-15 2015_12 "viable,mitotic cell cycle defective,female sterile" "oocyte,meiotic spindle,spindle pole,eye,macrochaeta,adult cuticle,chromosome,spindle" FBgn0085749 CR40574 http://flybase.net/reports/FBgn0085749.html FBan0040574 rRNA_gene CR40574 16-Dec-15 2015_12 FBgn0027080 Aats-tyr Tyrosyl-tRNA synthetase http://flybase.net/reports/FBgn0027080.html "FBgn0025537, FBgn0036630" protein_coding_gene "0004831=tyrosine-tRNA ligase activity, 0000049=tRNA binding, 0005524=ATP binding" 0006437=tyrosyl-tRNA aminoacylation 0005737=cytoplasm "dYARS, anon-EST:Posey261, YARS, CG4561, TyrRS, YRS, dTyrRS, tyrosyl-tRNA synthetase" "IPR002547=tRNA-binding domain, IPR002307=Tyrosine-tRNA ligase, IPR002305=Aminoacyl-tRNA synthetase, class Ic, IPR012340=Nucleic acid-binding, OB-fold, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG4561 16-Dec-15 2015_12 ENSDARG00000035913(yars) YGR185C(TYS1) ENSXETG00000027865(yars) ENSMUSG00000028811(Yars) ENSG00000134684(YARS) embryonic stage "

ubiquitous , embryonic/larval salivary gland

" "locomotor behavior defective,lethal,partially lethal - majority die,viable,decreased cell size,cell autonomous,somatic clone" "lysosome & larval fat body | somatic clone | cell autonomous,scutellar bristle" DRSC10430 I -1.817513107 0.79666709 0.800816708 0.562389039 0.025846277 -0.196815075 FBgn0069442 E(zip)12-5 E(zip)12-5 http://flybase.net/reports/FBgn0069442.html gene 5-Dec 16-Dec-15 2015_12 "lethal,recessive" FBgn0259955 CG42465 http://flybase.net/reports/FBgn0259955.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42465 16-Dec-15 2015_12 FBgn0259606 B0216 http://flybase.net/reports/FBgn0259606.html gene 16-Dec-15 2015_12 visible "antennal segment,leg,arista" FBgn0266681 CR45171 http://flybase.net/reports/FBgn0266681.html non_protein_coding_gene CR45171 16-Dec-15 2015_12 FBgn0013676 mt:CoIII mitochondrial Cytochrome c oxidase subunit III http://flybase.net/reports/FBgn0013676.html FBgn0002867 protein_coding_gene 0004129=cytochrome-c oxidase activity 0019646=aerobic electron transport chain "0005739=mitochondrion, 0016020=membrane, 0005751=mitochondrial respiratory chain complex IV" "cox3, Co III, III, COIII, mt-CO3, COX III, CG34074, cytochrome c oxidase subunit III, CO, CcO III, CO3, coxIII, cytochrome c, Cytochrome c oxidase subunit III, cytochrome c oxidase, CO III, COX, COXIII, CcO subunit III" "IPR024791=Cytochrome c oxidase subunit III, IPR013833=Cytochrome c oxidase, subunit III, 4-helical bundle, IPR000298=Cytochrome c oxidase subunit III domain" CG34074 16-Dec-15 2015_12 ENSDARG00000063912 Q0275(COX3) WBGene00010962(MTCE.23) "ENSMUSG00000064356,ENSMUSG00000064358" "ENSG00000198744,ENSG00000198938" FBgn0023472 anon-30Fb anon-30Fb http://flybase.net/reports/FBgn0023472.html gene 16-Dec-15 2015_12 FBgn0005446 l(1)v216 lethal (1) v216 http://flybase.net/reports/FBgn0005446.html gene l(1)216 16-Dec-15 2015_12 FBgn0051497 tRNA:CR31497 transfer RNA:CR31497 http://flybase.net/reports/FBgn0051497.html FBgn0060044 tRNA_gene 0033437=ACU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA[[Thr]], CR31497, tRNA:T:AGT:AE002708-e, chr3R.trna58-ThrAGT, AE002708.trna52-ThrAGT" CR31497 16-Dec-15 2015_12 FBgn0027242 l(1)G0270 lethal (1) G0270 http://flybase.net/reports/FBgn0027242.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053557 CG33557 http://flybase.net/reports/FBgn0053557.html FBgn0040938 protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus CG12648 "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG33557 16-Dec-15 2015_12 "ENSDARG00000067544,ENSDARG00000035695(scxa),ENSDARG00000011635(LOC567817),ENSDARG00000042857" "WBGene00001960(hlh-16),WBGene00001961(hlh-17),WBGene00009540(hlh-31),WBGene00013665(hlh-32)" "ENSXETG00000013826(),ENSXETG00000002557(tcf15),ENSXETG00000005692()" ENSMUSG00000028717(Tal1) "ENSG00000125878(TCF15),ENSG00000187786(SCXB),ENSG00000188686(SCXA)" viable FBgn0082335 HM781 HM781 http://flybase.net/reports/FBgn0082335.html gene 16-Dec-15 2015_12 FBgn0040218 fs(2)BP76 fs(2)BP76 http://flybase.net/reports/FBgn0040218.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0003690 telegraph telegraph http://flybase.net/reports/FBgn0003690.html gene tg 16-Dec-15 2015_12 "wing vein L2,posterior scutellar bristle" FBgn0000201 bn band http://flybase.net/reports/FBgn0000201.html gene 16-Dec-15 2015_12 "visible,recessive" "trident,adult thorax,microchaeta & thorax" FBgn0034595 CG15657 http://flybase.net/reports/FBgn0034595.html FBgn0063307 protein_coding_gene BcDNA:AT24036 CG15657 16-Dec-15 2015_12 FBgn0263204 HipHop::ms(3)K81 http://flybase.net/reports/FBgn0263204.html engineered_fusion_gene hiphop-k81 16-Dec-15 2015_12 FBgn0036570 IntS9 Integrator 9 http://flybase.net/reports/FBgn0036570.html protein_coding_gene "0034472=snRNA 3'-end processing, 0016180=snRNA processing, 0006378=mRNA polyadenylation, 0006379=mRNA cleavage" "0005847=mRNA cleavage and polyadenylation specificity factor complex, 0032039=integrator complex" "Ints9, CG5222, Int9" "IPR027074=Integrator complex subunit 9, IPR022712=Beta-Casp domain" CG5222 16-Dec-15 2015_12 ENSDARG00000067913 WBGene00017608(F19F10.12) ENSMUSG00000021975(Ints9) ENSG00000104299(INTS9) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0000621 e(y)5 enhancer of yellow 5 http://flybase.net/reports/FBgn0000621.html gene 16-Dec-15 2015_12 "female sterile,recessive,visible" "head bristle,macrochaeta,microchaeta" FBgn0010280 Taf4 TBP-associated factor 4 http://flybase.net/reports/FBgn0010280.html "FBgn0005542, FBgn0010419, FBgn0013958" protein_coding_gene "0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0003677=DNA binding, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0001092=TFIIA-class transcription factor binding" "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0007517=muscle organ development, 0006367=transcription initiation from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005669=transcription factor TFIID complex" "CG5444, TAF[[II]]110, dTAFII110, TAFII110, l(3)72Dj, dmTAF4, Taf110, TAF, TAF[II]110, TATA-associated factor 110, dTAF4, TFIID, d110, TBP associated factor 110, TBP-associated factor 110, TBP-associated factor 110kD, SY3-2 TAF110, lethal(3)72Dj, taf110, TBP-associated factor, Taf[[II]]110, TFIID 110, TAF110, TAF4, TAF[[II]], SR3-3, dTAF[[II]]110, p110" "IPR007900=Transcription initiation factor TFIID component TAF4, IPR003894=TAFH/NHR1, IPR009072=Histone-fold" CG5444 16-Dec-15 2015_12 ENSDARG00000070652 WBGene00006385(taf-4) ENSXETG00000001996(TAF4) ENSMUSG00000039117(Taf4a) ENSG00000130699(TAF4) "lethal,recessive,cell cycle defective,somatic clone,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of P-stage,some die during pharate adult stage" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC11297 IEK -2.292296628 0.766085108 -2.123428118 -0.381937944 1.830149585 0.906543716 FBgn0051768 CG31768 http://flybase.net/reports/FBgn0051768.html FBgn0064811 protein_coding_gene BcDNA:RH43029 16-Dec-15 2015_12 FBgn0028649 anon-55Ec anon-55Ec http://flybase.net/reports/FBgn0028649.html gene "D-1700, E-2000" 16-Dec-15 2015_12 FBgn0010482 l(2)01289 lethal (2) 01289 http://flybase.net/reports/FBgn0010482.html "FBgn0013956, FBgn0033098, FBgn0033099, FBgn0050444" protein_coding_gene 0003756=protein disulfide isomerase activity 0045454=cell redox homeostasis 0005886=plasma membrane "CG9435, CG30444, CG9432, Lethal (2) 01289, Fusion2, Fusion-2" "IPR012336=Thioredoxin-like fold, IPR013766=Thioredoxin domain" CG9432 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0033819 CG4714 http://flybase.net/reports/FBgn0033819.html FBgn0044720 protein_coding_gene anon-WO0140519.159 IPR025254=Domain of unknown function DUF4201 CG4714 16-Dec-15 2015_12 ENSMUSG00000050677(Ccdc96) viable FBgn0060345 l(3)S143517 lethal (3) S143517 http://flybase.net/reports/FBgn0060345.html gene 1435/17 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001101 ge genitalless http://flybase.net/reports/FBgn0001101.html gene gen 16-Dec-15 2015_12 "male sterile,recessive,viable,visible,melanotic mass phenotype,male" "male genitalia,macrochaeta,wing,melanotic mass,tergite" FBgn0082976 snoRNA:ë¬28S-3305a snoRNA:ë¬28S-3305a http://flybase.net/reports/FBgn0082976.html snoRNA_gene "Psi 28S-3305a, CR34619, psi28s-3305a" CR34619 16-Dec-15 2015_12 FBgn0028943 CG15638 http://flybase.net/reports/FBgn0028943.html protein_coding_gene BG:BACR48E02.1 CG15638 16-Dec-15 2015_12 viable FBgn0004036 yea2 yeast 2 http://flybase.net/reports/FBgn0004036.html gene 16-Dec-15 2015_12 FBgn0000714 fmf factor for male fertility http://flybase.net/reports/FBgn0000714.html gene factor of male fertility 16-Dec-15 2015_12 FBgn0000491 droopy droopy http://flybase.net/reports/FBgn0000491.html gene dr 16-Dec-15 2015_12 "visible,viable,fertile" "wing,alula" FBgn0069409 JJF177 JJF177 http://flybase.net/reports/FBgn0069409.html gene 16-Dec-15 2015_12 stress response defective FBgn0265957 CR44744 http://flybase.net/reports/FBgn0265957.html non_protein_coding_gene CR44744 16-Dec-15 2015_12 FBgn0085734 CR40450 http://flybase.net/reports/FBgn0085734.html FBan0040450 pseudogene_attribute CR40450 16-Dec-15 2015_12 FBgn0265887 CR44676 http://flybase.net/reports/FBgn0265887.html non_protein_coding_gene CR44676 16-Dec-15 2015_12 FBgn0033537 CG11834 http://flybase.net/reports/FBgn0033537.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265070 CR44181 http://flybase.net/reports/FBgn0265070.html non_protein_coding_gene CR44181 16-Dec-15 2015_12 FBgn0037076 ebd2 earthbound 2 http://flybase.net/reports/FBgn0037076.html protein_coding_gene 0003677=DNA binding 0007527=adult somatic muscle development CG12972 "IPR006600=HTH CenpB-type DNA-binding domain, IPR009057=Homeodomain-like, IPR007889=DNA binding HTH domain, Psq-type" CG12972 16-Dec-15 2015_12 "ENSG00000125817(CENPB),ENSG00000164296(TIGD6),ENSG00000180346(TIGD2)" "viable,fertile" dorsal medial muscle FBgn0065203 l(2)SH2288 lethal (2) SH2288 http://flybase.net/reports/FBgn0065203.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034249 RhoGAP54D Rho GTPase activating protein at 54D http://flybase.net/reports/FBgn0034249.html protein_coding_gene 0005096=GTPase activator activity "0007264=small GTPase mediated signal transduction, 0007480=imaginal disc-derived leg morphogenesis" "RhoGAP54D, CG6477" "IPR008936=Rho GTPase activation protein, IPR000198=Rho GTPase-activating protein domain" CG6477 16-Dec-15 2015_12 viable FBgn0031719 CG18269 http://flybase.net/reports/FBgn0031719.html protein_coding_gene IPR007970=Protein of unknown function DUF733 CG18269 16-Dec-15 2015_12 viable FBgn0265264 CG17097 http://flybase.net/reports/FBgn0265264.html "FBgn0032275, FBgn0066980" protein_coding_gene "0004806=triglyceride lipase activity, 0016298=lipase activity" "0006629=lipid metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space anon-SAGE:Wang-018 "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG17097 16-Dec-15 2015_12 ENSDARG00000018529(lipf) "YLR020C(YEH2),YLL012W(YEH1)" "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" FBgn0065806 l(2)SH0394 lethal (2) SH0394 http://flybase.net/reports/FBgn0065806.html gene l(2)SH2 0394 16-Dec-15 2015_12 "lethal,recessive" FBgn0036428 Gbs-70E Glycogen binding subunit 70E http://flybase.net/reports/FBgn0036428.html FBgn0062040 protein_coding_gene "0008599=protein phosphatase type 1 regulator activity, 0008157=protein phosphatase 1 binding, 2001069=glycogen binding" "0048149=behavioral response to ethanol, 0070873=regulation of glycogen metabolic process" "anon-WO0118547.400, CG9238" "IPR005036=CBM21 (carbohydrate binding type-21) domain, IPR017434=Protein phosphatase 1 regulatory subunit 3B/C/D, metazoa" CG9238 16-Dec-15 2015_12 "ENSDARG00000014554(ppp1r3cb),ENSDARG00000071005(ppp1r3ca),ENSDARG00000044691(ppp1r3b)" "YER054C(GIP2),YIL045W(PIG2)" WBGene00019211(H18N23.2) "ENSXETG00000020984(PPP1R3C),ENSXETG00000008154(ppp1r3b)" "ENSMUSG00000067279(Ppp1r3c),ENSMUSG00000046794(Ppp1r3b)" "ENSG00000119938(PPP1R3C),ENSG00000173281(PPP1R3B)" "hyperactive,conditional,chemical resistant,short lived,female semi-sterile,viable" FBgn0037491 CG1227 http://flybase.net/reports/FBgn0037491.html protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding" "0045793=positive regulation of cell size, 0006468=protein phosphorylation" "MPSK/PSK, Psk" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG1227 16-Dec-15 2015_12 ENSDARG00000037777(zgc:112393) YPL236C() WBGene00008424(D2045.7) ENSXETG00000019290(stk16) ENSMUSG00000026201(Stk16) ENSG00000115661(STK16) viable FBgn0028537 CG31775 http://flybase.net/reports/FBgn0028537.html "FBgn0047030, FBgn0047116, FBgn0051775, FBgn0063098" protein_coding_gene "BcDNA:LP08165, BcDNA:RH25462, BcDNA:RE38252, BG:DS00810.2" CG31775 16-Dec-15 2015_12 DRSC01413 IK -1.519455633 -1.062312123 -1.334795566 -0.953429441 -0.813126301 1.522373458 FBgn0033285 CG18449 http://flybase.net/reports/FBgn0033285.html protein_coding_gene "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG18449 16-Dec-15 2015_12 viable FBgn0264895 RapGAP1 Rap GTPase activating protein 1 http://flybase.net/reports/FBgn0264895.html "FBgn0085403, FBgn0031922, FBgn0014015, FBgn0053529, FBgn0040955, FBtr0079452, FBpp0079080, FBtr0079453, FBpp0079081, FBtr0079454, FBpp0079082, FBgn0031923" protein_coding_gene 0005096=GTPase activator activity "0002121=inter-male aggressive behavior, 0090630=activation of GTPase activity, 0007265=Ras protein signal transduction" 0060293=germ plasm "CG34374, Rapgap1, CG44086, Q9VM02_DROME, CG13790, RapGap1, CG13791, CG13789, CG33529, rapgap1, CG6682" "IPR000331=Rap GTPase activating protein domain, IPR003109=GoLoco motif" CG44086 16-Dec-15 2015_12 "ENSDARG00000056554(zgc:175180),ENSDARG00000053272,ENSDARG00000061551(zgc:153898)" WBGene00018734(F53A10.2) ENSXETG00000012970(RAP1GAP2) "ENSMUSG00000041351(Rap1gap),ENSMUSG00000038807(Rap1gap2)" "ENSG00000076864(RAP1GAP),ENSG00000132359(RAP1GAP2)" " larval stage , embryonic stage | stage >12 , embryonic stage | early , embryonic stage | stage 8-11 " " ommatidial precursor cluster

, garland cell

, embryonic peripheral nervous system

, pole cell

, embryonic/larval midgut

, larval optic lobe

, morphogenetic furrow

, ventral neurogenic region

, optic nerve

, morphogenetic furrow | posterior to

, eye disc

" DRSC02293 K -0.569615305 -0.295575372 -0.327940078 0.394825394 -1.559783334 -0.69270326 FBgn0043479 l(3)66EFg lethal (3) 66EFg http://flybase.net/reports/FBgn0043479.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067765 l(1)16-1-27 lethal (1) 16-1-27 http://flybase.net/reports/FBgn0067765.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065959 l(2)SH0042 lethal (2) SH0042 http://flybase.net/reports/FBgn0065959.html gene l(2)SH2 0042 16-Dec-15 2015_12 "lethal,recessive" FBgn0033117 CG3358 http://flybase.net/reports/FBgn0033117.html protein_coding_gene "0016888=endodeoxyribonuclease activity, producing 5'-phosphomonoesters" "IPR018228=Deoxyribonuclease, TatD-related, conserved site, IPR001130=TatD family" CG3358 16-Dec-15 2015_12 ENSDARG00000036924(zgc:92362) YBL055C() ENSXETG00000017477(TATDN1) ENSMUSG00000050891(Tatdn1) ENSG00000147687(TATDN1) "partially lethal - majority die,some die during pupal stage" FBgn0035184 CG9094 http://flybase.net/reports/FBgn0035184.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083295 E(smoDN)1889 Enhancer of smoDN 1889 http://flybase.net/reports/FBgn0083295.html gene 16-Dec-15 2015_12 FBgn0265987 CR44766 http://flybase.net/reports/FBgn0265987.html non_protein_coding_gene CR44766 16-Dec-15 2015_12 FBgn0259936 Uhg3 Uhg3 http://flybase.net/reports/FBgn0259936.html "FBgn0083125, FBgn0047311" non_protein_coding_gene "BcDNA:GH14469, dUhg-like 3, putative noncoding RNA 012:2L, CR32957, GH14469, dUhg3, putative RNA non-coding gene, pncr012:2L" CR32957 16-Dec-15 2015_12 FBgn0027212 l(1)G0346 lethal (1) G0346 http://flybase.net/reports/FBgn0027212.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0264747 CG44005 http://flybase.net/reports/FBgn0264747.html FBgn0085281 protein_coding_gene CG34252 CG44005 16-Dec-15 2015_12 FBgn0000720 fol folded wings http://flybase.net/reports/FBgn0000720.html gene 16-Dec-15 2015_12 visible wing FBgn0030738 CG9915 http://flybase.net/reports/FBgn0030738.html protein_coding_gene 0003677=DNA binding "0006351=transcription, DNA-templated" 0005634=nucleus "IPR017923=Transcription factor IIS, N-terminal" CG9915 16-Dec-15 2015_12 WBGene00008729(F13B12.1) ENSXETG00000002963(Q505H7_XENTR) ENSMUSG00000024384(Iws1) ENSG00000163166(IWS1) DRSC21565 K 0.455239793 0.24318825 0.689885855 1.032420403 -0.274329083 2.035005342 FBgn0023428 lad ladybird http://flybase.net/reports/FBgn0023428.html gene 16-Dec-15 2015_12 visible "pigment cell,eye" FBgn0086023 snoRNA:Me28S-A2589a http://flybase.net/reports/FBgn0086023.html snoRNA_gene "Me28S-Am2589a, Me28S-A2589a, CR34652" CR34652 16-Dec-15 2015_12 FBgn0086344 FGM222E05 http://flybase.net/reports/FBgn0086344.html nuclear_gene 16-Dec-15 2015_12 FBgn0036609 CG13039 http://flybase.net/reports/FBgn0036609.html FBgn0063300 protein_coding_gene BcDNA:AT27312 CG13039 16-Dec-15 2015_12 "viable,fertile" DRSC09920 I 1.819788267 -0.326099151 0.685699411 0.938916328 -0.169303213 -0.551693835 FBgn0085559 CG41038 http://flybase.net/reports/FBgn0085559.html FBan0041038 protein_coding_gene 16-Dec-15 2015_12 FBgn0031559 CG3513 http://flybase.net/reports/FBgn0031559.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG3513 16-Dec-15 2015_12 ENSDARG00000069736 ENSXETG00000016886(SPINT3) "ENSMUSG00000074595(Wfdc6a),ENSMUSG00000070531(Wfdc6b),ENSMUSG00000017733(Spinlw1)" "partially lethal - majority die,some die during pupal stage" FBgn0029714 CG3527 http://flybase.net/reports/FBgn0029714.html protein_coding_gene 0070037=rRNA (pseudouridine) methyltransferase activity "0009267=cellular response to starvation, 0022008=neurogenesis, 0031167=rRNA methylation, 0042742=defense response to bacterium, 0040018=positive regulation of multicellular organism growth" dNEP1 "IPR029028=Alpha/beta knot methyltransferases, IPR005304=Ribosomal biogenesis, methyltransferase, EMG1/NEP1" CG3527 16-Dec-15 2015_12 ENSDARG00000056914(zgc:136360) YLR186W(EMG1) WBGene00012652(Y39A1A.14) ENSXETG00000023917(EMG1) ENSMUSG00000004268(Emg1) ENSG00000126749 "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0262519 Mi-2 Mi-2 http://flybase.net/reports/FBgn0262519.html "FBgn0013591, FBgn0010735, FBgn0011790, FBgn0028080, FBgn0028245, FBgn0024536" protein_coding_gene "0003677=DNA binding, 0016887=ATPase activity, 0070615=nucleosome-dependent ATPase activity, 0003678=DNA helicase activity, 0003682=chromatin binding, 0031491=nucleosome binding, 0004386=helicase activity, 0005524=ATP binding, 0008270=zinc ion binding, 0005515=protein binding, 0004003=ATP-dependent DNA helicase activity, 0008026=ATP-dependent helicase activity" "0007517=muscle organ development, 0006357=regulation of transcription from RNA polymerase II promoter, 0071923=negative regulation of cohesin localization to chromatin, 0007283=spermatogenesis, 0045892=negative regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis, 0042766=nucleosome mobilization" "0005634=nucleus, 0005829=cytosol, 0035327=transcriptionally active chromatin, 0005700=polytene chromosome, 0016581=NuRD complex" "Mi 2, pha, M-i2, Mi-2 ortholog, PHD-containing ATPase, hip76, Chd4, 0854/01, Pha, dMI-2, MI2, dMi-2, CG8103, hb-interacting protein 76, l(3)S085401, dMi, l(3)j3D4, Mi2, l(3)01058, lethal (3) L1243, l(3)S000606, l(3)A154.3M3, l(3)76BDe, Dm-Mi-2, 0006/06, dMi2, l(3)L1243, MI-2" "IPR012958=CHD, N-terminal, IPR000330=SNF2-related, N-terminal domain, IPR001650=Helicase, C-terminal, IPR001841=Zinc finger, RING-type, IPR019787=Zinc finger, PHD-finger, IPR016197=Chromo domain-like, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR000953=Chromo/chromo shadow domain, IPR012957=CHD, C-terminal 2, IPR019786=Zinc finger, PHD-type, conserved site, IPR009463=Domain of unknown function DUF1087, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR009462=Domain of unknown function DUF1086, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR023780=Chromo domain" CG8103 16-Dec-15 2015_12 "ENSDARG00000063535(si:ch211-51m24.3),ENSDARG00000025789,ENSDARG00000044932" "WBGene00000482(chd-3),WBGene00002637(let-418)" ENSXETG00000012991(CHD3) "ENSMUSG00000063870(Chd4),ENSMUSG00000005045(Chd5),ENSMUSG00000018474(Chd3)" "ENSG00000111642(CHD4),ENSG00000116254(CHD5),ENSG00000170004(CHD3)" embryonic stage DRSC11222 IEK -1.958727306 -0.520254985 -1.855189637 -0.125224747 2.174374019 4.602912116 FBgn0015334 anon-100Aa anon-100Aa http://flybase.net/reports/FBgn0015334.html gene T1 16-Dec-15 2015_12 FBgn0011159 l(1)Q237 lethal (1) Q237 http://flybase.net/reports/FBgn0011159.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0261291 CheA86a Chemosensory protein A 86a http://flybase.net/reports/FBgn0261291.html "FBgn0067313, FBgn0053698" protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG33698, CheA86a" IPR010512=Protein of unknown function DUF1091 CG33698 16-Dec-15 2015_12 FBgn0062522 l(3)ff29 lethal (3) ff29 http://flybase.net/reports/FBgn0062522.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0002537 Lcp6 Larval cuticle protein 6 http://flybase.net/reports/FBgn0002537.html gene "0008010=structural constituent of chitin-based larval cuticle, 0042302=structural constituent of cuticle" "L[[3]]CP6, LCP6" IPR000618=Insect cuticle protein 16-Dec-15 2015_12 electrophoretic variant FBgn0022041 l(2)k08317 lethal (2) k08317 http://flybase.net/reports/FBgn0022041.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267112 CR45552 http://flybase.net/reports/FBgn0267112.html non_protein_coding_gene CR45552 16-Dec-15 2015_12 FBgn0032943 Tsp39D Tetraspanin 39D http://flybase.net/reports/FBgn0032943.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp39D, CG8666" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG8666 16-Dec-15 2015_12 WBGene00006633(tsp-7) ENSXETG00000017488(cd63) viable FBgn0050275 CG30275 http://flybase.net/reports/FBgn0050275.html FBgn0034771 protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process CG13520 "IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain" CG30275 16-Dec-15 2015_12 ENSG00000089101(C20orf26) "partially lethal - majority die,some die during pupal stage" FBgn0038398 sxe2 sex-specific enzyme 2 http://flybase.net/reports/FBgn0038398.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0004620=phospholipase activity" 0016042=lipid catabolic process "male sex-specific enzyme 2, CG4979" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG4979 16-Dec-15 2015_12 viable FBgn0025842 E(var)104 E(var)104 http://flybase.net/reports/FBgn0025842.html gene E-104 16-Dec-15 2015_12 FBgn0042142 CG18819 http://flybase.net/reports/FBgn0042142.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032409 Ced-12 Ced-12 http://flybase.net/reports/FBgn0032409.html protein_coding_gene 0005515=protein binding "0007520=myoblast fusion, 0016203=muscle attachment, 0007417=central nervous system development, 0090630=activation of GTPase activity, 0007015=actin filament organization, 0007298=border follicle cell migration, 0016477=cell migration" "0005875=microtubule associated complex, 0005634=nucleus, 0005737=cytoplasm" "ced-12, Ced12, elmo, ELMO, CG5336, Elmo, dCed-12, engulfment and cell motility, Dced-12, dced-12" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006816=ELMO domain, IPR024574=Domain of unknown function DUF3361, IPR016024=Armadillo-type fold" CG5336 16-Dec-15 2015_12 "ENSDARG00000042126,ENSDARG00000019258(elmo1)" WBGene00000426(ced-12) "ENSXETG00000007361(BC081328.1),ENSXETG00000013823(ELMO3)" "ENSMUSG00000041112(Elmo1),ENSMUSG00000017670(Elmo2),ENSMUSG00000014791(Elmo3)" "ENSG00000155849(ELMO1),ENSG00000062598(ELMO2),ENSG00000102890(ELMO3)" "lethal,neuroanatomy defective,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "muscle fiber,germline clone,embryonic myoblast,presumptive embryonic/larval muscle system,lateral longitudinal fascicle,border follicle cell,somatic clone,thorax,embryonic myoblast | embryonic stage 16,presumptive embryonic/larval muscle system | embryonic stage 16,reticular neuropil associated glial cell,gamma Kenyon cell,muscle attachment site,tendon cell,muscle fiber | third instar larval stage" FBgn0038916 dnd dead end http://flybase.net/reports/FBgn0038916.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0035147=branch fusion, open tracheal system, 0007264=small GTPase mediated signal transduction, 0042384=cilium assembly" "0015630=microtubule cytoskeleton, 0005737=cytoplasm" "Dnd, Arf-like 3, CG6560, ADP-ribosylation factor-like 3, Q9VD64, ARL3, Arf-like3, Arf-like-3, Arl3" "IPR024156=Small GTPase superfamily, ARF type, IPR006689=Small GTPase superfamily, ARF/SAR type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain" CG6560 16-Dec-15 2015_12 "ENSDARG00000071409(arl3),ENSDARG00000060743,ENSDARG00000015122(zgc:110197),ENSDARG00000015404(arl3l2),ENSDARG00000028846(arl3l1)" WBGene00000188(arl-3) ENSXETG00000015225(ARL3) ENSMUSG00000025035(Arl3) ENSG00000138175(ARL3) "visible,dominant,wild-type,recessive" "dorsal branch primordium,dorsal trunk primordium" FBgn0028591 l(3)05218 lethal (3) 05218 http://flybase.net/reports/FBgn0028591.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259202 CG42306 http://flybase.net/reports/FBgn0259202.html protein_coding_gene Dromel_CG5469_FBtr0086654_gint3_uORF CG42306 16-Dec-15 2015_12 FBgn0002535 Lcp4 Larval cuticle protein 4 http://flybase.net/reports/FBgn0002535.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "IV, Gene IV, L[[3]]CP4, 4, DmelLcp4, LCP4, CG2044, LCP-4, cuticle p. IV, lcp4" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG2044 16-Dec-15 2015_12 " embryonic stage , pupal stage | 7-13 hr , larval stage , larval stage | third instar stage 2 , larval stage | late third instar larval stage " " integumentary system

, organism

" viable FBgn0013971 Gpr5B G protein-coupled receptor 5B http://flybase.net/reports/FBgn0013971.html gene 16-Dec-15 2015_12 FBgn0028201 l(3)S018801 lethal (3) S018801 http://flybase.net/reports/FBgn0028201.html gene 0188/01 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0040769 CG12431 http://flybase.net/reports/FBgn0040769.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265257 CG44271 http://flybase.net/reports/FBgn0265257.html protein_coding_gene 0008270=zinc ion binding "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site" CG44271 16-Dec-15 2015_12 FBgn0039863 CG1815 http://flybase.net/reports/FBgn0039863.html protein_coding_gene "0008270=zinc ion binding, 0005080=protein kinase C binding" "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR001841=Zinc finger, RING-type, IPR019787=Zinc finger, PHD-finger, IPR002893=Zinc finger, MYND-type, IPR000313=PWWP domain, IPR001487=Bromodomain, IPR019786=Zinc finger, PHD-type, conserved site" CG1815 16-Dec-15 2015_12 "ENSDARG00000007601(zmynd8),ENSDARG00000011932(prkcbp1l)" ENSMUSG00000039671(Zmynd8) ENSG00000101040(ZMYND8) viable FBgn0020350 anon-44Aa anon-44Aa http://flybase.net/reports/FBgn0020350.html gene transcription unit B 16-Dec-15 2015_12 FBgn0266632 CR45139 http://flybase.net/reports/FBgn0266632.html non_protein_coding_gene CR45139 16-Dec-15 2015_12 FBgn0260258 GSd321 http://flybase.net/reports/FBgn0260258.html gene 16-Dec-15 2015_12 lethal FBgn0040904 CG15577 http://flybase.net/reports/FBgn0040904.html protein_coding_gene CG15577 16-Dec-15 2015_12 viable FBgn0001881 l(1)Yi29 lethal (1) Yi29 http://flybase.net/reports/FBgn0001881.html gene 16-Dec-15 2015_12 lethal FBgn0002012 l(2)36Fe lethal (2) 36Fe http://flybase.net/reports/FBgn0002012.html gene "l(2)E134, 36Fe, Fe" 16-Dec-15 2015_12 lethal FBgn0025345 anon-17Ab anon-17Ab http://flybase.net/reports/FBgn0025345.html gene unnamed 16-Dec-15 2015_12 FBgn0044497 DTD45.1 DTD45.1 http://flybase.net/reports/FBgn0044497.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034907 CG5539 http://flybase.net/reports/FBgn0034907.html protein_coding_gene IPR004345=TB2/DP1/HVA22-related protein CG5539 16-Dec-15 2015_12 viable FBgn0266328 CR44993 http://flybase.net/reports/FBgn0266328.html non_protein_coding_gene CR44993 16-Dec-15 2015_12 FBgn0051272 CG31272 http://flybase.net/reports/FBgn0051272.html FBgn0037830 protein_coding_gene "0005215=transporter activity, 0016298=lipase activity" "0006810=transport, 0055085=transmembrane transport, 0006629=lipid metabolic process" "0016021=integral component of membrane, 0030672=synaptic vesicle membrane" CG6529 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG31272 16-Dec-15 2015_12 FBgn0024306 SS3-5 Suppressor of GMR-sina 3-5 http://flybase.net/reports/FBgn0024306.html gene 16-Dec-15 2015_12 FBgn0053422 5SrRNA:CR33422 5SrRNA:CR33422 http://flybase.net/reports/FBgn0053422.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33422 CR33422 16-Dec-15 2015_12 FBgn0010158 lzl lozengelike http://flybase.net/reports/FBgn0010158.html gene 16-Dec-15 2015_12 "visible,male fertile,female fertile" eye FBgn0267942 CR46222 http://flybase.net/reports/FBgn0267942.html non_protein_coding_gene lincRNA.705 CR46222 16-Dec-15 2015_12 FBgn0085728 CG42226 http://flybase.net/reports/FBgn0085728.html FBan0041431 protein_coding_gene 16-Dec-15 2015_12 FBgn0265798 CR44587 http://flybase.net/reports/FBgn0265798.html non_protein_coding_gene lincRNA.118 CR44587 16-Dec-15 2015_12 FBgn0004190 snRNA:U6:96Ac small nuclear RNA U6 at 96Ac http://flybase.net/reports/FBgn0004190.html "FBgn0003455, FBgn0003939, FBgn0003940, FBgn0051539" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005688=U6 snRNP "U6snRNA, U6, snRNA-b, U6 RNA, snRNA[[4]], small nuclear RNA U6, K1, U6snRNA96Ac, snRNA4, snRNA:U6, U6-96Ac, dU6, U6:96Ac, U6-3, U6 snRNA, U6-3 small nuclear RNA, DU6-3, CR31539, snRNA6, small nuclear RNA b" CR31539 16-Dec-15 2015_12 FBgn0086727 Dje5 http://flybase.net/reports/FBgn0086727.html gene Dje 5 16-Dec-15 2015_12 FBgn0031801 CG9498 http://flybase.net/reports/FBgn0031801.html protein_coding_gene "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG9498 16-Dec-15 2015_12 "WBGene00007810(C29F7.1),WBGene00007811(C29F7.2),WBGene00014192(nhr-246)" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC03235 I -0.595652173 1.514980297 0.590529056 0.341236634 -0.312163311 -0.464585315 FBgn0259428 C840 http://flybase.net/reports/FBgn0259428.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0035286 CG13924 http://flybase.net/reports/FBgn0035286.html protein_coding_gene CG13924 16-Dec-15 2015_12 "viable,female fertile" FBgn0035865 CG7201 http://flybase.net/reports/FBgn0035865.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG7201 16-Dec-15 2015_12 viable FBgn0060768 l(3)S062310 lethal (3) S062310 http://flybase.net/reports/FBgn0060768.html gene 0623/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031566 CG2818 http://flybase.net/reports/FBgn0031566.html protein_coding_gene "0008081=phosphoric diester hydrolase activity, 2001070=starch binding" 0006629=lipid metabolic process "IPR030395=Glycerophosphodiester phosphodiesterase domain, IPR013783=Immunoglobulin-like fold, IPR002044=Carbohydrate binding module family 20, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR013784=Carbohydrate-binding-like fold, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG2818 16-Dec-15 2015_12 ENSDARG00000016011(gpcpd1) "WBGene00011511(T05H10.7),WBGene00019612(K10B3.6)" ENSMUSG00000027346(Gpcpd1) ENSG00000125772(GPCPD1) viable FBgn0025125 su(RpII140Z36)S3 su(RpII140Z36)S3 http://flybase.net/reports/FBgn0025125.html gene Z36[S3] 16-Dec-15 2015_12 FBgn0022259 l(2)k00808 lethal (2) k00808 http://flybase.net/reports/FBgn0022259.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033725 Cpr49Ac Cuticular protein 49Ac http://flybase.net/reports/FBgn0033725.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0040003=chitin-based cuticle development, 0042381=hemolymph coagulation" "0031012=extracellular matrix, 0005576=extracellular region" CG8502 IPR000618=Insect cuticle protein CG8502 16-Dec-15 2015_12 viable FBgn0259733 tal-AA http://flybase.net/reports/FBgn0259733.html protein_coding_gene "0007015=actin filament organization, 0002009=morphogenesis of an epithelium" "Pep4, pri, tal, CG42387, ORF AA, Dm_3R:52381, Dm4, ORF4" CG42387 16-Dec-15 2015_12 FBgn0024659 l(2)k07403 lethal (2) k07403 http://flybase.net/reports/FBgn0024659.html gene 74/3 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,anterior compartment" FBgn0037923 CG6813 http://flybase.net/reports/FBgn0037923.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus CG31372 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG6813 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "viable,fertile" FBgn0053533 lectin-37Db lectin-37Db http://flybase.net/reports/FBgn0053533.html "FBgn0032778, FBgn0040094" protein_coding_gene 0005534=galactose binding 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "Drosophila lectin 3, AC007082c, CG9978, DL3, CG33533, AC 007082C, unnamed, lectin" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG33533 16-Dec-15 2015_12 "ENSDARG00000046092(LOC799269),ENSDARG00000069025,ENSDARG00000035891" "WBGene00020585(clec-178),WBGene00018692(F52E1.2)" "ENSMUSG00000059639(Clec4a4),ENSMUSG00000031495(Cd209d),ENSMUSG00000030148(Clec4a2),ENSMUSG00000043832(Clec4a3),ENSMUSG00000067767(Clec4b2),ENSMUSG00000049037(Clec4a1),ENSMUSG00000030147(Clec4b1),ENSMUSG00000023349(Clec4n),ENSMUSG00000030144(Clec4d)" "ENSG00000111729(CLEC4A),ENSG00000198178(CLEC4C)" FBgn0261734 EC2388 http://flybase.net/reports/FBgn0261734.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0260776 CG42570 http://flybase.net/reports/FBgn0260776.html protein_coding_gene new ORF CG42570 16-Dec-15 2015_12 FBgn0010664 l(2)10505 lethal (2) 10505 http://flybase.net/reports/FBgn0010664.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005674 Aats-glupro Glutamyl-prolyl-tRNA synthetase http://flybase.net/reports/FBgn0005674.html FBgn0027089 protein_coding_gene "0004827=proline-tRNA ligase activity, 0004818=glutamate-tRNA ligase activity, 0005524=ATP binding" "0006433=prolyl-tRNA aminoacylation, 0006424=glutamyl-tRNA aminoacylation" "0017101=aminoacyl-tRNA synthetase multienzyme complex, 0005737=cytoplasm" "p200, GluProRS, GluRS, EPRS, Aats-glu, Glutamyl-tRNA synthetase, aminoacyl-tRNA synthetase, Glu-ProRS, AATS, FBpp0083898, AATs-GluPro, glutamyl-prolyl-tRNA synthetase, Bifunctional aminoacyl-tRNA synthetase, transfer RNA-Glu-Pro aminoacyl synthetase, GluPro-RS, CG5394, glutamyl-prolyl-tRA synthetase, Aa-tRNA-syn-glupro, ERS" "IPR002314=Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR000738=WHEP-TRS domain, IPR010987=Glutathione S-transferase, C-terminal-like, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR000924=Glutamyl/glutaminyl-tRNA synthetase, IPR020059=Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain, IPR020061=Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR017449=Prolyl-tRNA synthetase, class II, IPR004499=Proline-tRNA ligase, class IIa, archaeal-type, IPR009068=S15/NS1, RNA-binding, IPR020058=Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain, IPR011035=Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain, IPR004154=Anticodon-binding, IPR004526=Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic, IPR016061=Proline-tRNA ligase, class II, C-terminal, IPR020056=Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site" CG5394 16-Dec-15 2015_12 ENSDARG00000060494 YHR020W() WBGene00001337(ears-1) ENSXETG00000002724(EPRS) ENSMUSG00000026615(Eprs) ENSG00000136628(EPRS) embryonic stage

ubiquitous "female fertile,reduced,lethal" DRSC14095 K -0.578235006 0.346191897 -0.186586759 0.265234653 -1.179654268 1.530766105 FBgn0031042 CG14221 http://flybase.net/reports/FBgn0031042.html protein_coding_gene 0015035=protein disulfide oxidoreductase activity "0006662=glycerol ether metabolic process, 0045454=cell redox homeostasis" "IPR012336=Thioredoxin-like fold, IPR017937=Thioredoxin, conserved site, IPR013766=Thioredoxin domain, IPR005746=Thioredoxin" CG14221 16-Dec-15 2015_12 ENSXETG00000001083(TXNDC6) viable FBgn0024689 fws four way stop http://flybase.net/reports/FBgn0024689.html "FBgn0027736, FBgn0027744, FBgn0032641" protein_coding_gene "0007112=male meiosis cytokinesis, 0006891=intra-Golgi vesicle-mediated transport, 0007290=spermatid nucleus elongation, 0061024=membrane organization, 0043147=meiotic spindle stabilization, 0000916=actomyosin contractile ring contraction, 0007111=meiosis II cytokinesis, 0007110=meiosis I cytokinesis" "0005794=Golgi apparatus, 0017119=Golgi transport complex" "dCOG5, Fws, Four-way stop, Drosophila Cog5, Cog5, FWS, anon-EST:Posey186, anon-EST:Posey162, CG6549, COG5, Four Way Stop" IPR019465=Conserved oligomeric Golgi complex subunit 5 CG6549 16-Dec-15 2015_12 ENSDARG00000008235(si:dkey-217k21.3) WBGene00016608(cogc-5) ENSMUSG00000035933 ENSG00000164597(COG5) "meiotic cell cycle defective,male,cytokinesis defective,mitotic cell cycle defective,recessive,viable" "spermatid & nucleus | supernumeraryqua1374),Nebenkern,spindle & meiotic telophase I | malequa1374),contractile ring & meiotic telophase I | malequa1374),spindle & meiotic telophase II | malequa1374),contractile ring & meiotic telophase II | malequa1374),spermatid & nucleus | supernumerary,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male" DRSC29678 IK 1.507880744 -0.176093941 0.248858866 0.204749529 1.235833111 1.890138981 FBgn0031321 Tgt tRNA-guanine transglycosylase http://flybase.net/reports/FBgn0031321.html protein_coding_gene 0008479=queuine tRNA-ribosyltransferase activity 0008616=queuosine biosynthetic process "tgt, TGT, CG4947" "IPR004803=Queuine tRNA-ribosyltransferase, IPR002616=tRNA-guanine(15) transglycosylase-like" CG4947 16-Dec-15 2015_12 ENSDARG00000043105(qtrt1) WBGene00006566(tgt-1) ENSMUSG00000002825(Qtrt1) ENSG00000213339(QTRT1) viable FBgn0038388 CG4287 http://flybase.net/reports/FBgn0038388.html protein_coding_gene CG4287 16-Dec-15 2015_12 "viable,fertile,wild-type,lethal - all die before end of larval stage,some die during larval stage" larva FBgn0013614 l(3)L1159 lethal (3) L1159 http://flybase.net/reports/FBgn0013614.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029968 Ir7g Ionotropic receptor 7g http://flybase.net/reports/FBgn0029968.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "IR7g, DmelIR7g, ionotropic receptor 7g, CG15325" CG15325 16-Dec-15 2015_12 viable FBgn0033140 CG12836 http://flybase.net/reports/FBgn0033140.html protein_coding_gene mdcds_19139 IPR005334=Tctex-1 CG12836 16-Dec-15 2015_12 "ENSDARG00000054882(LOC793976),ENSDARG00000039344(tctex1d1)" "ENSMUSG00000047671(Tctex1d4),ENSMUSG00000028523(Tctex1d1)" viable FBgn0265636 CR44443 http://flybase.net/reports/FBgn0265636.html non_protein_coding_gene lincRNA.259 CR44443 16-Dec-15 2015_12 FBgn0053411 5SrRNA:CR33411 5SrRNA:CR33411 http://flybase.net/reports/FBgn0053411.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33411 CR33411 16-Dec-15 2015_12 FBgn0033005 CG3107 http://flybase.net/reports/FBgn0033005.html FBan0003107 protein_coding_gene "0004222=metalloendopeptidase activity, 0046872=metal ion binding" 0006508=proteolysis 0005759=mitochondrial matrix "IPR011765=Peptidase M16, N-terminal, IPR011237=Peptidase M16 domain, IPR007863=Peptidase M16, C-terminal, IPR013578=Peptidase M16C associated, IPR011249=Metalloenzyme, LuxS/M16 peptidase-like" CG3107 16-Dec-15 2015_12 ENSDARG00000038563(pitrm1) YDR430C(CYM1) ENSXETG00000009818(PITRM1) ENSMUSG00000021193(Pitrm1) ENSG00000107959(PITRM1) viable FBgn0011339 l(3)j2E11 lethal (3) j2E11 http://flybase.net/reports/FBgn0011339.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022539 Gld::Dpse\Gld Gld http://flybase.net/reports/FBgn0022539.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0011489 l(3)neo59 lethal (3) neo59 http://flybase.net/reports/FBgn0011489.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0250867 CG42238 http://flybase.net/reports/FBgn0250867.html protein_coding_gene CG9266 CG42238 16-Dec-15 2015_12 FBgn0259362 C389 http://flybase.net/reports/FBgn0259362.html gene 16-Dec-15 2015_12 visible "wing hair,chaeta" FBgn0000692 flrdP flight reduced P http://flybase.net/reports/FBgn0000692.html gene 16-Dec-15 2015_12 "jumping defective,bang sensitive,uncoordinated,conditional,flight defective" FBgn0016067 slbo::Rat\C-EBP-ë± C-EBP-ë± http://flybase.net/reports/FBgn0016067.html engineered_fusion_gene slbo::Rat\C/EBP-alpha 16-Dec-15 2015_12 FBgn0023541 Cyp4d14 Cyp4d14 http://flybase.net/reports/FBgn0023541.html FBgn0029602 protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG3540, EG:152A3.2, CYP4D14, cytochrome P450, 4d14" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG3540 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0024533 l(3)L1022 lethal (3) L1022 http://flybase.net/reports/FBgn0024533.html gene "EP(3)3334, LD11808" 16-Dec-15 2015_12 "lethal,recessive" FBgn0083284 E(smoDN)2162 Enhancer of smoDN 2162 http://flybase.net/reports/FBgn0083284.html gene 16-Dec-15 2015_12 FBgn0051926 CG31926 http://flybase.net/reports/FBgn0051926.html FBgn0031342 protein_coding_gene 0004190=aspartic-type endopeptidase activity "0007306=eggshell chorion assembly, 0006508=proteolysis" 0042600=chorion "CG10872, aspartic-type endopeptidase" "IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain, IPR001461=Aspartic peptidase" CG31926 16-Dec-15 2015_12 FBgn0065547 l(2)SH1046 lethal (2) SH1046 http://flybase.net/reports/FBgn0065547.html gene l(2)SH2 1046 16-Dec-15 2015_12 "lethal,recessive" FBgn0033761 CG8778 http://flybase.net/reports/FBgn0033761.html protein_coding_gene "0017091=AU-rich element binding, 0004300=enoyl-CoA hydratase activity" "0009631=cold acclimation, 0008152=metabolic process" 0005875=microtubule associated complex Enoyl-CoA hydratase "IPR018376=Enoyl-CoA hydratase/isomerase, conserved site, IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily, IPR014748=Crontonase, C-terminal" CG8778 16-Dec-15 2015_12 ENSDARG00000042975(auh) WBGene00001154(ech-5) ENSXETG00000000805(auh) ENSMUSG00000021460(Auh) ENSG00000148090(AUH) "viable,fertile" FBgn0001028 Fs(3)Ava Female sterile (3) Avar http://flybase.net/reports/FBgn0001028.html gene 0018991=oviposition "Fs(3)Sz2, Fs(3)Avar" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,dominant,maternal effect,some die during embryonic stage" "ovary,maternal effect" FBgn0261375 Dox-3 Dopa oxidase-3 http://flybase.net/reports/FBgn0261375.html FBgn0000487 gene "Dox3, Dox, Dopa oxidase, Diphenol oxidase-3" 16-Dec-15 2015_12 "electrophoretic variant,fast,slow,viable" FBgn0024921 Trn Transportin http://flybase.net/reports/FBgn0024921.html protein_coding_gene "0008536=Ran GTPase binding, 0008320=protein transmembrane transporter activity" "0006909=phagocytosis, 0035167=larval lymph gland hemopoiesis, 0042306=regulation of protein import into nucleus, 0022008=neurogenesis, 0006606=protein import into nucleus" 0005643=nuclear pore "IMPbeta2, transportin, CG7398, Transportin, dTRN, Tm, Trn1, TRN" "IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG7398 16-Dec-15 2015_12 "ENSDARG00000035390(tnpo1),ENSDARG00000038239(tnpo2)" YBR017C(KAP104) WBGene00002076(imb-2) "ENSXETG00000016812(TNPO1),ENSXETG00000004771(TNPO2)" "ENSMUSG00000009470(Tnpo1),ENSMUSG00000031691(Tnpo2)" "ENSG00000083312(TNPO1),ENSG00000105576(TNPO2)" "lethal,neuroanatomy defective,partially lethal - majority die,visible,female sterile,viable" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,embryonic/larval brain" DRSC11309 EK -0.891989817 -0.119561299 -0.96755615 -2.849460769 1.294085931 1.766691323 FBgn0027650 l(2)50B lethal (2) 50B http://flybase.net/reports/FBgn0027650.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0037626 CG8236 http://flybase.net/reports/FBgn0037626.html protein_coding_gene CG8236 16-Dec-15 2015_12 "viable,fertile" FBgn0261477 slim scruin like at the midline http://flybase.net/reports/FBgn0261477.html "FBgn0026173, FBgn0034349, FBgn0021787" protein_coding_gene 0032874=positive regulation of stress-activated MAPK cascade 0031462=Cul2-RING ubiquitin ligase complex "lethal (2) s1866, CG5186, l(2)s1866" "IPR006652=Kelch repeat type 1, IPR015915=Kelch-type beta propeller" CG5186 16-Dec-15 2015_12 ENSDARG00000007764(klhdc10) WBGene00013461(Y67H2A.2) ENSXETG00000016301(TEgg142i20.1) ENSMUSG00000029775(Klhdc10) ENSG00000128607(KLHDC10) FBgn0266134 c189 http://flybase.net/reports/FBgn0266134.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0032126 CG13113 http://flybase.net/reports/FBgn0032126.html protein_coding_gene 0007306=eggshell chorion assembly 0042600=chorion CG13113 16-Dec-15 2015_12 viable FBgn0003646 Su(z)4 Suppressor of zeste 4 http://flybase.net/reports/FBgn0003646.html gene 16-Dec-15 2015_12 "lethal,recessive" pigment cell FBgn0033748 vis vismay http://flybase.net/reports/FBgn0033748.html FBgn0026155 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005515=protein binding, 0042826=histone deacetylase binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003714=transcription corepressor activity" "0045893=positive regulation of transcription, DNA-templated, 0007283=spermatogenesis" 0005634=nucleus "zuker-aly-like a, TGIFa, dTGIFa, CG8821, zaa, achi/vis, Vismay" "IPR001356=Homeobox domain, IPR008422=Homeobox KN domain, IPR009057=Homeodomain-like" CG8821 16-Dec-15 2015_12 "ENSDARG00000002601(irx7),ENSDARG00000009510(irx1a),ENSDARG00000031138(irx3b),ENSDARG00000056594(irx1b),ENSDARG00000067576,ENSDARG00000034043(irx5a)" " adult stage , embryonic stage -- adult stage " " organism

, testis | restricted

, testis

" " embryonic stage , adult stage , adult stage | male , larval stage " " organism

, egg chamber

, spermatid

, spermatocyte

, testis

, dorsal mesothoracic disc

, ovary

" "viable,visible" "trichogen cell,supernumerary" FBgn0038903 RpI12 RpI12 http://flybase.net/reports/FBgn0038903.html protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003676=nucleic acid binding, 0008270=zinc ion binding" "0006351=transcription, DNA-templated, 0006360=transcription from RNA polymerase I promoter" 0005736=DNA-directed RNA polymerase I complex CG13418 "IPR001222=Zinc finger, TFIIS-type, IPR019761=DNA-directed RNA polymerase M, 15kDa subunit, conserved site, IPR012164=DNA-directed RNA polymerase, subunit C11/M/9" CG13418 16-Dec-15 2015_12 ENSDARG00000036070(znrd1) YJR063W(RPA12) WBGene00007616(C15H11.8) ENSMUSG00000036315(Znrd1) "ENSG00000066379(ZNRD1),ENSG00000206502,ENSG00000206429" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065260 l(2)SH2088 lethal (2) SH2088 http://flybase.net/reports/FBgn0065260.html gene l(2)SH2 2088 16-Dec-15 2015_12 "lethal,recessive" FBgn0262982 CG43290 http://flybase.net/reports/FBgn0262982.html protein_coding_gene CG43290 16-Dec-15 2015_12 FBgn0262990 CR43298 http://flybase.net/reports/FBgn0262990.html non_protein_coding_gene lincRNA.943 CR43298 16-Dec-15 2015_12 FBgn0029894 CG14440 http://flybase.net/reports/FBgn0029894.html protein_coding_gene CG14440 16-Dec-15 2015_12 viable FBgn0265639 CR44446 http://flybase.net/reports/FBgn0265639.html non_protein_coding_gene lincRNA.264 CR44446 16-Dec-15 2015_12 FBgn0004589 Eig71Eb Ecdysone-induced gene 71Eb http://flybase.net/reports/FBgn0004589.html protein_coding_gene 0042742=defense response to bacterium 0005576=extracellular region "71E-Gene-II, gene-II, Gene II, L71-2, L71, II, gene II, CG7355" IPR003475=Insect protein of unknown function CG7355 16-Dec-15 2015_12 DRSC11149 K 0.654948817 0.327867619 -0.038734697 0.218238894 -0.323373148 -1.567154995 FBgn0065553 l(2)SH1024 lethal (2) SH1024 http://flybase.net/reports/FBgn0065553.html gene l(2)SH2 1024 16-Dec-15 2015_12 "lethal,recessive" FBgn0040366 CG11398 http://flybase.net/reports/FBgn0040366.html FBgn0029571 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0048813=dendrite morphogenesis EG:BACR42I17.11 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG11398 16-Dec-15 2015_12 "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC" FBgn0035159 CG13896 http://flybase.net/reports/FBgn0035159.html protein_coding_gene CG13896 16-Dec-15 2015_12 viable FBgn0267785 CR46116 http://flybase.net/reports/FBgn0267785.html non_protein_coding_gene CR46116 16-Dec-15 2015_12 FBgn0002370 l(3)91Fb lethal (3) 91Fb http://flybase.net/reports/FBgn0002370.html FBgn0002376 gene "l(3)92Ab, l(3)BE50, l(3)BE51, l(3)BE52, l(3)C3, l(DIX43)c3, C3, Complementation group 3" 16-Dec-15 2015_12 "lethal,recessive" FBgn0015412 l(1)14BCa lethal (1) 14BCa http://flybase.net/reports/FBgn0015412.html gene "l(1)14Ce, l(1)14-12" 16-Dec-15 2015_12 "lethal,recessive" FBgn0031802 ppk7 pickpocket 7 http://flybase.net/reports/FBgn0031802.html protein_coding_gene "0015280=ligand-gated sodium channel activity, 0005272=sodium channel activity" 0006814=sodium ion transport 0016021=integral component of membrane "CG9499, PPK7" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG9499 16-Dec-15 2015_12 "viable,lethal" FBgn0025504 l(3)72Fc lethal (3) 72Fc http://flybase.net/reports/FBgn0025504.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013323 Ptth Prothoracicotropic hormone http://flybase.net/reports/FBgn0013323.html FBgn0031269 protein_coding_gene "0005184=neuropeptide hormone activity, 0005125=cytokine activity, 0018445=prothoracicotrophic hormone activity" "0044060=regulation of endocrine process, 0006954=inflammatory response, 0045998=positive regulation of ecdysteroid biosynthetic process, 0008293=torso signaling pathway, 0007552=metamorphosis, 0046957=negative phototaxis" "0005576=extracellular region, 0043196=varicosity" "PTTH, ptth, prothoracicotropic hormone, CG13687, phm, prothoracicotopic hormone, Prothoracicotropic hormone" "IPR029034=Cystine-knot cytokine, IPR010345=Interleukin-17 family" CG13687 16-Dec-15 2015_12 "small body,developmental rate defective,size defective,viable,phototaxis defective" "wing,embryo" FBgn0264630 balloon balloon http://flybase.net/reports/FBgn0264630.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0024762 EC66 EC66 http://flybase.net/reports/FBgn0024762.html gene 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation" FBgn0051823 CG31823 http://flybase.net/reports/FBgn0051823.html FBgn0028933 protein_coding_gene 0004185=serine-type carboxypeptidase activity 0006508=proteolysis "BG:DS00365.3, CG7647" "IPR029058=Alpha/Beta hydrolase fold, IPR018202=Peptidase S10, serine carboxypeptidase, active site, IPR001563=Peptidase S10, serine carboxypeptidase" CG31823 16-Dec-15 2015_12 ENSDARG00000040072(scpep1) YGL203C(KEX1) WBGene00012530(Y32F6A.5) ENSXETG00000020061(SCPEP1) ENSMUSG00000000278(Scpep1) ENSG00000121064(SCPEP1) viable FBgn0002080 l(2)49Fi lethal (2) 49Fi http://flybase.net/reports/FBgn0002080.html gene "l(2)vr20, l(2)vr29" 16-Dec-15 2015_12 lethal FBgn0040085 p74 p74 http://flybase.net/reports/FBgn0040085.html gene 16-Dec-15 2015_12 FBgn0065413 l(2)SH1560 lethal (2) SH1560 http://flybase.net/reports/FBgn0065413.html gene l(2)SH2 1560 16-Dec-15 2015_12 "lethal,recessive" FBgn0030638 CG11655 http://flybase.net/reports/FBgn0030638.html protein_coding_gene 0008508=bile acid:sodium symporter activity 0016020=membrane IPR002657=Bile acid:sodium symporter/arsenical resistance protein Acr3 CG11655 16-Dec-15 2015_12 ENSDARG00000030090(zgc:85947) WBGene00044650(Y71G10AR.4) "ENSXETG00000012551(SLC10A6),ENSXETG00000009830(SLC10A4)" "ENSMUSG00000032806(Slc10a3),ENSMUSG00000058921(Slc10a5)" "ENSG00000126903(SLC10A3),ENSG00000205184" "viable,fertile" FBgn0260080 2L0439 http://flybase.net/reports/FBgn0260080.html gene "0035001=dorsal trunk growth, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone,dorsal trunk primordium" FBgn0030037 CG12125 http://flybase.net/reports/FBgn0030037.html protein_coding_gene IPR019392=Protein of unknown function DUF2217 CG12125 16-Dec-15 2015_12 "ENSDARG00000020596(fam73a),ENSDARG00000013626" WBGene00010465(K01D12.6) "ENSXETG00000018962(FAM73B),ENSXETG00000013134(FAM73A)" "ENSMUSG00000026858(Fam73b),ENSMUSG00000054942(Fam73a)" "ENSG00000148343(FAM73B),ENSG00000180488(FAM73A)" viable FBgn0051050 CG31050 http://flybase.net/reports/FBgn0051050.html FBgn0045120 protein_coding_gene "NEST:bs32b08, bs32b08.y1" CG31050 16-Dec-15 2015_12 viable FBgn0261990 CG42808 http://flybase.net/reports/FBgn0261990.html "FBgn0033857, FBan0013335, FBgn0033858, FBgn0064931" protein_coding_gene "CG13335, CG6183" CG42808 16-Dec-15 2015_12 FBgn0004741 l(3)85Dh lethal (3) 85Dh http://flybase.net/reports/FBgn0004741.html gene 16-Dec-15 2015_12 lethal FBgn0065518 l(2)SH1140 lethal (2) SH1140 http://flybase.net/reports/FBgn0065518.html gene l(2)SH2 1140 16-Dec-15 2015_12 "lethal,recessive" FBgn0001911 l(2)24Fc lethal (2) 24Fc http://flybase.net/reports/FBgn0001911.html gene "jf7, l(2)jf7" 16-Dec-15 2015_12 lethal FBgn0003201 rar1 radiation-resistant on 1 http://flybase.net/reports/FBgn0003201.html gene radioresistant 16-Dec-15 2015_12 "radiation resistant,chemical resistant" FBgn0020532 l(3)1A1 lethal (3) 1A1 http://flybase.net/reports/FBgn0020532.html gene 1A1 16-Dec-15 2015_12 FBgn0263100 pyr::ths http://flybase.net/reports/FBgn0263100.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0267151 CR45591 http://flybase.net/reports/FBgn0267151.html non_protein_coding_gene CR45591 16-Dec-15 2015_12 FBgn0004915 TfIIB Transcription factor IIB http://flybase.net/reports/FBgn0004915.html FBgn0023206 protein_coding_gene "0008134=transcription factor binding, 0008270=zinc ion binding, 0017025=TBP-class protein binding" "0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0001174=transcriptional start site selection at RNA polymerase II promoter, 0051101=regulation of DNA binding" "0005634=nucleus, 0005667=transcription factor complex" "TfllB, dmTFIIB, dTFIIB, CG5193, dTfIIB, TFIIB, Tfiib" "IPR013137=Zinc finger, TFIIB-type, IPR013763=Cyclin-like, IPR013150=Transcription factor TFIIB, cyclin-like domain, IPR023486=Transcription factor TFIIB, conserved site, IPR000812=Transcription factor TFIIB" CG5193 16-Dec-15 2015_12 ENSDARG00000019489(gtf2b) YPR086W(SUA7) WBGene00006648(ttb-1) ENSXETG00000006091(gtf2b) ENSMUSG00000028271(Gtf2b) ENSG00000137947(GTF2B) embryonic stage DRSC03454 IEK -0.017377511 2.684900986 -1.726682066 -0.415752645 1.198984549 2.086247614 FBgn0019808 aos::shg argos::shg http://flybase.net/reports/FBgn0019808.html engineered_fusion_gene "gil::shg, argos::shg" 16-Dec-15 2015_12 "visible,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing margin,posterior,wing margin bristle,posterior crossvein,posterior compartment,eye,ommatidium,interommatidial bristle,ectopic,microchaeta & mesothoracic tergumpnr-MD237,microchaeta | supernumerary & mesothoracic tergumpnr-MD237,embryonic/first instar larval cuticle,dorsal,scutum,head,wing blade" FBgn0058068 CR40068 http://flybase.net/reports/FBgn0058068.html FBan0040068 pseudogene_attribute CG40068 CR40068 16-Dec-15 2015_12 FBgn0266002 CR44776 http://flybase.net/reports/FBgn0266002.html non_protein_coding_gene CR44776 16-Dec-15 2015_12 FBgn0033911 VGAT Vesicular GABA Transporter http://flybase.net/reports/FBgn0033911.html protein_coding_gene "0015171=amino acid transmembrane transporter activity, 0015495=gamma-aminobutyric acid:proton symporter activity" "0030431=sleep, 0003333=amino acid transmembrane transport, 0007632=visual behavior" "CG8394, vGAT, CG8394.2, vesicular GABA transporter, VIAAT" "IPR013057=Amino acid transporter, transmembrane domain" CG8394 16-Dec-15 2015_12 ENSDARG00000059775 YJR001W(AVT1) WBGene00006783(unc-47) ENSXETG00000025497(slc38a1) ENSMUSG00000037771(Slc32a1) ENSG00000101438(SLC32A1) "optomotor response defective,behavior defective,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0043590 EK2-5 EK2-5 http://flybase.net/reports/FBgn0043590.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264329 CG43788 http://flybase.net/reports/FBgn0264329.html protein_coding_gene CG43788 16-Dec-15 2015_12 FBgn0037973 CG18547 http://flybase.net/reports/FBgn0037973.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process "IPR020471=Aldo/keto reductase subgroup, IPR023210=NADP-dependent oxidoreductase domain, IPR001395=Aldo/keto reductase" CG18547 16-Dec-15 2015_12 YMR041C(ARA2) WBGene00003176(mec-14) ENSXETG00000016911() "viable,fertile" FBgn0083272 E(smoDN)2590 Enhancer of smoDN 2590 http://flybase.net/reports/FBgn0083272.html gene 16-Dec-15 2015_12 FBgn0004682 grg giant ring gland http://flybase.net/reports/FBgn0004682.html gene "l(1)grg, l(1)giant ring gland" 16-Dec-15 2015_12 "lethal,recessive" "ring gland,neurosecretory neuron" FBgn0261531 CG42659 http://flybase.net/reports/FBgn0261531.html protein_coding_gene noncoding_3557 CG42659 16-Dec-15 2015_12 FBgn0035733 CG8641 http://flybase.net/reports/FBgn0035733.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" 0007264=small GTPase mediated signal transduction 0016020=membrane Q9VS10 "IPR020849=Small GTPase superfamily, Ras type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG8641 16-Dec-15 2015_12 ENSDARG00000019274 "ENSXETG00000005738(RASD1),ENSXETG00000013420(rasd2)" "ENSMUSG00000049892(Rasd1),ENSMUSG00000034472(Rasd2)" "ENSG00000108551(RASD1),ENSG00000100302(RASD2)" viable FBgn0265269 CG15425 http://flybase.net/reports/FBgn0265269.html "FBgn0031591, FBgn0066942" protein_coding_gene anon-SAGE:Wang-056 CG15425 16-Dec-15 2015_12 FBgn0028630 ksh-17 ksh-17 http://flybase.net/reports/FBgn0028630.html gene 16-Dec-15 2015_12 FBgn0267675 CR46011 http://flybase.net/reports/FBgn0267675.html non_protein_coding_gene CR46011 16-Dec-15 2015_12 FBgn0003620 Su(var)2-142 Suppressor of variegation 2-142 http://flybase.net/reports/FBgn0003620.html gene 16-Dec-15 2015_12 FBgn0040613 CG12509 http://flybase.net/reports/FBgn0040613.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267713 CR46046 http://flybase.net/reports/FBgn0267713.html non_protein_coding_gene CR46046 16-Dec-15 2015_12 FBgn0037388 CG14676 http://flybase.net/reports/FBgn0037388.html protein_coding_gene CG14676 16-Dec-15 2015_12 viable FBgn0065915 l(2)SH0169 lethal (2) SH0169 http://flybase.net/reports/FBgn0065915.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000912 fs(1)M122 female sterile (1) M122 http://flybase.net/reports/FBgn0000912.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0017375 l(1)lpr-1 lethal (1) lpr-1 http://flybase.net/reports/FBgn0017375.html gene 16-Dec-15 2015_12 lethal "puparium,prepupal cuticle" FBgn0028230 l(3)S004209b lethal (3) S004209b http://flybase.net/reports/FBgn0028230.html gene "l(3)S004209, 0042/09" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037718 P58IPK P58IPK http://flybase.net/reports/FBgn0037718.html FBgn0046231 protein_coding_gene 0004860=protein kinase inhibitor activity 0012505=endomembrane system "dIPK, inhibitor of protein kinases, SD05682.5prime, CG8286, BEST:SD05682" "IPR001440=Tetratricopeptide repeat 1, IPR001623=DnaJ domain, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG8286 16-Dec-15 2015_12 "ENSDARG00000041110(dnajc3),ENSDARG00000017874(prkri)" "WBGene00001025(dnj-7),WBGene00001046(dnj-28)" ENSXETG00000006458(DNAJC3) ENSMUSG00000022136(Dnajc3) ENSG00000102580(DNAJC3) viable FBgn0026163 tRNA:K5:84ABc tRNA:K5:84ABc http://flybase.net/reports/FBgn0026163.html "FBgn0003793, FBgn0011901, FBgn0051487, FBgn0060175" tRNA_gene 0033443=AAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "lys5:84ABc, CR31487, tRNA:K:TTT:AE002699-b, BG:DS00276.3, AE002699.trna5-LysTTT, chr3R.trna78-LysTTT, tRNA:K5" CR31487 16-Dec-15 2015_12 FBgn0083967 Muted Muted ortholog (H. sapiens) http://flybase.net/reports/FBgn0083967.html "FBgn0063677, FBan0007071, FBgn0038949" protein_coding_gene "0030133=transport vesicle, 0031083=BLOC-1 complex" "Dromel_CG7071_FBtr0084211_uORF, muted, Muted, NP_001036744, CG34131" IPR017243=Biogenesis of lysosome-related organelles complex 1 subunit 5 CG34131 16-Dec-15 2015_12 FBgn0032391 escl escl http://flybase.net/reports/FBgn0032391.html protein_coding_gene 0042054=histone methyltransferase activity 0070734=histone H3-K27 methylation 0035098=ESC/E(Z) complex "ESC, ESC1, ESC-LIKE, CG5202-PA, ESCL, esc-like, CG5202" "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG5202 16-Dec-15 2015_12 ENSDARG00000040548(eed) WBGene00003224(mes-6) ENSXETG00000010440(eed) ENSMUSG00000030619 ENSG00000074266(EED) "viable,fertile" FBgn0085678 CG41541 http://flybase.net/reports/FBgn0085678.html FBan0041541 protein_coding_gene 16-Dec-15 2015_12 FBgn0023029 l(2)CA2 lethal (2) CA2 http://flybase.net/reports/FBgn0023029.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011207 pelo pelota http://flybase.net/reports/FBgn0011207.html protein_coding_gene "0071025=RNA surveillance, 0007141=male meiosis I, 0007054=spindle assembly involved in male meiosis I, 0001745=compound eye morphogenesis, 0000212=meiotic spindle organization, 0048749=compound eye development, 0070966=nuclear-transcribed mRNA catabolic process, no-go decay, 0007283=spermatogenesis, 0006412=translation, 0048132=female germ-line stem cell asymmetric division, 0008315=meiotic G2/MI transition, 0007067=mitotic nuclear division, 0007140=male meiosis, 0048137=spermatocyte division, 0051078=meiotic nuclear envelope disassembly, 0007126=meiotic nuclear division, 0070481=nuclear-transcribed mRNA catabolic process, non-stop decay, 0030718=germ-line stem cell maintenance" "0005737=cytoplasm, 0005634=nucleus" "CG3959, Pelota, ms(2)01559" "IPR004405=Translation release factor pelota, IPR005140=eRF1 domain 1/Pelota-like, IPR005141=eRF1 domain 2, IPR005142=eRF1 domain 3, IPR029064=50S ribosomal protein L30e-like" CG3959 16-Dec-15 2015_12 ENSDARG00000055477(pelo) YNL001W(DOM34) WBGene00011280(R74.6) ENSXETG00000018368(pelo) ENSMUSG00000042275(Pelo) ENSG00000152684(PELO) embryonic stage -- adult stage "viable,fertile,male sterile,partially lethal - majority die,increased cell death,female sterile,partially,meiotic cell cycle defective,recessive,cold sensitive,wild-type" "female germline stem cell,germline cyst,follicle cell,somatic clone,egg chamber,spermatocyte,spermatid,eye,ommatidium,interommatidial bristle,ovary,germarium,Nebenkern" FBgn0014232 l(2)31Eo lethal (2) 31Eo http://flybase.net/reports/FBgn0014232.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028062 l(3)S092708 lethal (3) S092708 http://flybase.net/reports/FBgn0028062.html gene 0927/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0031036 CG14220 http://flybase.net/reports/FBgn0031036.html protein_coding_gene 0070822=Sin3-type complex "cg14220, Sds3, SDS3" IPR013907=Sds3-like CG14220 16-Dec-15 2015_12 ENSDARG00000041406 ENSXETG00000022377(SUDS3) ENSMUSG00000066900(Suds3) ENSG00000111707(SUDS3) FBgn0044431 LYT106 LYT106 http://flybase.net/reports/FBgn0044431.html gene 16-Dec-15 2015_12 FBgn0264602 CR43951 http://flybase.net/reports/FBgn0264602.html non_protein_coding_gene CR43951 16-Dec-15 2015_12 FBgn0027270 l(1)G0209 lethal (1) G0209 http://flybase.net/reports/FBgn0027270.html gene 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" melanotic mass FBgn0033174 CG11125 http://flybase.net/reports/FBgn0033174.html protein_coding_gene IPR027012=Enkurin domain CG11125 16-Dec-15 2015_12 ENSDARG00000043550(si:ch211-220d9.3) ENSXETG00000015620(BC088484.1) ENSMUSG00000013155(E130303B06Rik) ENSG00000124074(C16orf48) viable FBgn0067070 Mpp10 Mpp10 http://flybase.net/reports/FBgn0067070.html gene dMpp10 16-Dec-15 2015_12 FBgn0001894 l(2)21Ea lethal (2) 21Ea http://flybase.net/reports/FBgn0001894.html gene "l(2)neh8, l(2)neh-8" 16-Dec-15 2015_12 lethal FBgn0016790 bose bose http://flybase.net/reports/FBgn0016790.html gene 16-Dec-15 2015_12 macrochaeta FBgn0015939 fs(2)PC4-U fs(2)PC4-U http://flybase.net/reports/FBgn0015939.html gene "l(2)PC4-T, fs(2)PC4-T" 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0002037 l(2)37Da lethal (2) 37Da http://flybase.net/reports/FBgn0002037.html gene l(2)OE23 16-Dec-15 2015_12 "partially lethal - majority die,heat sensitive,visible" genitalia FBgn0013477 l(1)1Ab lethal (1) 1Ab http://flybase.net/reports/FBgn0013477.html gene 16-Dec-15 2015_12 FBgn0040338 TfIIA-S-2 TfIIA-S-2 http://flybase.net/reports/FBgn0040338.html FBgn0029551 protein_coding_gene "0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005672=transcription factor TFIIA complex" "CG11639, tfiia-s-2, EG:BACR7A4.7, TFIIA" "IPR015871=Transcription initiation factor IIA, gamma subunit, C-terminal, IPR015872=Transcription initiation factor IIA, gamma subunit, N-terminal, IPR003194=Transcription initiation factor IIA, gamma subunit, IPR009083=Transcription factor IIA, helical, IPR009088=Transcription factor IIA, beta-barrel" CG11639 16-Dec-15 2015_12 YKL058W(TOA2) WBGene00013736(Y111B2A.13) viable FBgn0003564 Su(Gl)57 Suppressor of Glued 57 http://flybase.net/reports/FBgn0003564.html gene 16-Dec-15 2015_12 FBgn0015438 l(1)5Aa lethal (1) 5Aa http://flybase.net/reports/FBgn0015438.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259405 EP-666 http://flybase.net/reports/FBgn0259405.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0260385 GSd481 http://flybase.net/reports/FBgn0260385.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0015418 l(1)16ACb lethal (1) 16ACb http://flybase.net/reports/FBgn0015418.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065196 l(2)SH2323 lethal (2) SH2323 http://flybase.net/reports/FBgn0065196.html gene l(2)SH2 2323 16-Dec-15 2015_12 "lethal,recessive" FBgn0021756 blis blisterwing http://flybase.net/reports/FBgn0021756.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 2L-F 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,distal" FBgn0051789 CG31789 http://flybase.net/reports/FBgn0051789.html protein_coding_gene CG31789 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0011237 ptl pointless http://flybase.net/reports/FBgn0011237.html gene 0007320=insemination 16-Dec-15 2015_12 male semi-sterile FBgn0267701 CR46034 http://flybase.net/reports/FBgn0267701.html non_protein_coding_gene CR46034 16-Dec-15 2015_12 FBgn0065300 l(2)SH1989 lethal (2) SH1989 http://flybase.net/reports/FBgn0065300.html gene l(2)SH2 1989 16-Dec-15 2015_12 "lethal,recessive" FBgn0011154 l(1)Q232 lethal (1) Q232 http://flybase.net/reports/FBgn0011154.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0013679 mt:ND1 mitochondrial NADH-ubiquinone oxidoreductase chain 1 http://flybase.net/reports/FBgn0013679.html FBgn0002867 protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0055114=oxidation-reduction process "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I, 0016020=membrane" "URF1, mt ND1, ND-1, nitrogen dehydrogenase 1, nd1, ND1, CG34092, mt-ND1, nad1, MT-ND1, NADH dehydrogenase 1" "IPR018086=NADH:ubiquinone oxidoreductase, subunit 1, conserved site, IPR001694=NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H" CG34092 16-Dec-15 2015_12 ENSDARG00000063895 WBGene00010959(MTCE.11) ENSMUSG00000064341 ENSG00000198888 FBgn0032429 CG5446 http://flybase.net/reports/FBgn0032429.html FBgn0063026 protein_coding_gene 0035220=wing disc development BcDNA:RE36920 IPR009643=Heat shock factor binding 1 CG5446 16-Dec-15 2015_12 "ENSDARG00000041921(hsbp1),ENSDARG00000069425" WBGene00002002(hsb-1) ENSXETG00000025864(hsbp1) ENSMUSG00000031839(Hsbp1) ENSG00000166530 viable FBgn0050076 CG30076 http://flybase.net/reports/FBgn0050076.html protein_coding_gene CG30076 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0021855 l(2)k14517 lethal (2) k14517 http://flybase.net/reports/FBgn0021855.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029587 CG14797 http://flybase.net/reports/FBgn0029587.html protein_coding_gene CG14797 16-Dec-15 2015_12 FBgn0267311 CR45747 http://flybase.net/reports/FBgn0267311.html non_protein_coding_gene CR45747 16-Dec-15 2015_12 FBgn0085056 tre-1 tre-1 http://flybase.net/reports/FBgn0085056.html "CR34649, CG34649" 16-Dec-15 2015_12 FBgn0259253 EP-B5 http://flybase.net/reports/FBgn0259253.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0266698 CR45188 http://flybase.net/reports/FBgn0266698.html non_protein_coding_gene CR45188 16-Dec-15 2015_12 FBgn0053654 CG33654 http://flybase.net/reports/FBgn0053654.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33654 16-Dec-15 2015_12 FBgn0266499 s-171.2 http://flybase.net/reports/FBgn0266499.html gene 16-Dec-15 2015_12 FBgn0032321 YL-1 YL-1 http://flybase.net/reports/FBgn0032321.html protein_coding_gene 0004402=histone acetyltransferase activity "0043486=histone exchange, 0006355=regulation of transcription, DNA-templated, 0016573=histone acetylation, 0010629=negative regulation of gene expression" "0035267=NuA4 histone acetyltransferase complex, 0005634=nucleus" "dYL-1, CG4621" "IPR008895=Vps72/YL1 family, IPR013272=Vps72/YL1, C-terminal" CG4621 16-Dec-15 2015_12 "ENSDARG00000063718(vps72),ENSDARG00000060629" YDR485C(VPS72) WBGene00007645(C17E4.6) ENSMUSG00000008958(Vps72) ENSG00000163159(VPS72) "viable,visible,female semi-sterile,female fertile" trichogen cell DRSC23798 K -0.454799507 1.24803293 0.810624856 0.609134302 1.887901613 1.007531081 FBgn0067766 kol koldewey http://flybase.net/reports/FBgn0067766.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 lethal "nurse cell,germline clone,egg" FBgn0001240 Hx Hexaptera http://flybase.net/reports/FBgn0001240.html gene 16-Dec-15 2015_12 "visible,dominant" "adult prothoracic segment,adult epidermis" FBgn0011423 l(3)j9E7 lethal (3) j9E7 http://flybase.net/reports/FBgn0011423.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039049 CG6726 http://flybase.net/reports/FBgn0039049.html protein_coding_gene 0004046=aminoacylase activity 0006520=cellular amino acid metabolic process 0005737=cytoplasm "IPR010159=N-acyl-L-amino-acid amidohydrolase, IPR011650=Peptidase M20, dimerisation domain, IPR002933=Peptidase M20" CG6726 16-Dec-15 2015_12 "ENSDARG00000004845(LOC100001620),ENSDARG00000038475(zgc:55605)" "WBGene00007507(C10C5.3),WBGene00007508(C10C5.4),WBGene00007509(C10C5.5),WBGene00015509(C06A6.4)" ENSXETG00000000089(acy1) ENSMUSG00000023262(Acy1) ENSG00000114786(ACY1) viable FBgn0267824 PRAS40 PRAS40 ortholog http://flybase.net/reports/FBgn0267824.html "FBgn0001332, FBgn0010518, FBgn0033940" protein_coding_gene "0032007=negative regulation of TOR signaling, 0048011=neurotrophin TRK receptor signaling pathway, 0038202=TORC1 signaling" 0005829=cytosol "dPRAS40, PRAS40, CG46146, CG10109" IPR026682=AKT1 substrate 1 protein CG46146 16-Dec-15 2015_12 FBgn0034849 CG3500 http://flybase.net/reports/FBgn0034849.html FBgn0061468 protein_coding_gene BcDNA:AT03803 IPR007277=Transmembrane adaptor Erv26 CG3500 16-Dec-15 2015_12 ENSDARG00000044584(zgc:110022) YHR181W(SVP26) ENSXETG00000021530(TEX261) ENSMUSG00000014748(Tex261) ENSG00000144043(TEX261) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035020 CG13585 http://flybase.net/reports/FBgn0035020.html FBgn0063295 protein_coding_gene BcDNA:AT28250 "IPR020309=Uncharacterised protein family, CD034/YQF4" CG13585 16-Dec-15 2015_12 ENSDARG00000005799(zgc:77713) WBGene00007923(C34C12.4) ENSXETG00000012838(C4orf34) ENSMUSG00000037822(1110003E01Rik) ENSG00000163683(C4orf34) "viable,fertile" FBgn0016798 l(1)18 lethal (1) 18 http://flybase.net/reports/FBgn0016798.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0001344 l(1)1Da lethal (1) 1Da http://flybase.net/reports/FBgn0001344.html gene "HM454, HM-454" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266518 Dpit47 DNA polymerase interacting tpr containing protein of 47kD http://flybase.net/reports/FBgn0266518.html "FBgn0033083, FBgn0043045" protein_coding_gene 0005634=nucleus "cn20, CG3189" "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG3189 16-Dec-15 2015_12 ENSDARG00000044405(ttc4) YBR155W(CNS1) WBGene00015916(C17G10.2) ENSXETG00000020003(TTC4) ENSMUSG00000025413(Ttc4) ENSG00000221971 DRSC04985 E -0.379222834 -1.4049634 -2.957148118 -0.346833677 0.743502592 0.192099193 FBgn0265836 CG44625 http://flybase.net/reports/FBgn0265836.html protein_coding_gene CG44625 16-Dec-15 2015_12 FBgn0011665 Mse9.4 Modifier of split & Enhancer of split 9.4 http://flybase.net/reports/FBgn0011665.html gene MSE9.4 16-Dec-15 2015_12 FBgn0259702 CG42356 http://flybase.net/reports/FBgn0259702.html FBgn0052308 protein_coding_gene CG32308 CG42356 16-Dec-15 2015_12 FBgn0265753 CR44560 http://flybase.net/reports/FBgn0265753.html non_protein_coding_gene lincRNA.551 CR44560 16-Dec-15 2015_12 FBgn0083250 E(smoDN)N Enhancer of smoDN group N http://flybase.net/reports/FBgn0083250.html gene 0007224=smoothened signaling pathway Group N 16-Dec-15 2015_12 "lethal,recessive" FBgn0259139 glo glorund http://flybase.net/reports/FBgn0259139.html "FBgn0037954, FBgn0062090, FBgn0069092" protein_coding_gene "0005515=protein binding, 0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "0006417=regulation of translation, 0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0060810=intracellular mRNA localization involved in pattern specification process, 0042060=wound healing, 0046427=positive regulation of JAK-STAT cascade, 0051276=chromosome organization, 0045451=pole plasm oskar mRNA localization, 0048477=oogenesis" 0043234=protein complex "l(3)S11046, 110/46, p67-K, l(3)S011046, Glorund, cg6946, p67, anon-WO0118547.328, Glo, CG6946" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG6946 16-Dec-15 2015_12 "ENSDARG00000053021(grsf1),ENSDARG00000005551(hnrnph1l)" WBGene00020936(hrpf-1) "ENSXETG00000013850(GRSF1),ENSXETG00000018321(hnrph1)" "ENSMUSG00000042079(Hnrnpf),ENSMUSG00000007850(Hnrnph1),ENSMUSG00000045427(Hnrnph2),ENSMUSG00000020069(Hnrnph3)" "ENSG00000169813(HNRNPF),ENSG00000169045(HNRNPH1),ENSG00000126945(HNRNPH2),ENSG00000096746(HNRNPH3)" DRSC16145 IK -0.654184709 -1.553854985 -0.614357653 -0.232783258 -1.987972557 -1.658163712 FBgn0030566 ë_NACtes4 http://flybase.net/reports/FBgn0030566.html protein_coding_gene CG18313 IPR002715=Nascent polypeptide-associated complex NAC domain CG18313 16-Dec-15 2015_12 viable FBgn0262809 CG43180 http://flybase.net/reports/FBgn0262809.html protein_coding_gene chr2L_1199311_1199719.0 16-Dec-15 2015_12 FBgn0005391 Yp2 Yolk protein 2 http://flybase.net/reports/FBgn0005391.html "FBgn0000847, FBgn0004046" protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0005198=structural molecule activity" "0007548=sex differentiation, 0048477=oogenesis, 0022008=neurogenesis, 0007296=vitellogenesis" "0016590=ACF complex, 0005811=lipid particle, 0005875=microtubule associated complex" "fs(1)M35, VG2, fs(1)m35, YP[[2]], fs(1)A59, VIT2Dm, fs(1)K313, yolk protein, CG2979, YP, yp2, YPII, YP2, vitellogenin, yp, YP-2, yolk protein 2" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG2979 16-Dec-15 2015_12 "viable,fertile,electrophoretic variant,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0000141 ascutex ascutex http://flybase.net/reports/FBgn0000141.html gene 0005725=intercalary heterochromatin "ASX, asx" 16-Dec-15 2015_12 "visible,recessive,body color defective" "leg,mesothoracic suture,scutellum" FBgn0044062 GTD74-135-2 GTD74-135-2 http://flybase.net/reports/FBgn0044062.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031306 CG4577 http://flybase.net/reports/FBgn0031306.html protein_coding_gene CG4577 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0283465 mir-312-as mir-312-as stem loop http://flybase.net/reports/FBgn0283465.html miRNA_gene dme-mir-312-as 16-Dec-15 2015_12 FBgn0015862 anon-2216 anon-2216 http://flybase.net/reports/FBgn0015862.html gene 16-Dec-15 2015_12 FBgn0069303 X-87-21 X-87-21 http://flybase.net/reports/FBgn0069303.html gene 0007399=nervous system development 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,neurogenic phenotype,recessive,some die during embryonic stage" FBgn0036970 Spn77Bc Serpin 77Bc http://flybase.net/reports/FBgn0036970.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction "0005615=extracellular space, 0005576=extracellular region" "Spn77, CG6289" "IPR000215=Serpin family, IPR023796=Serpin domain" CG6289 16-Dec-15 2015_12 "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile" DRSC10689 K -0.776142602 0.296785787 -0.246607215 -0.081125441 -0.897519964 -1.618398823 FBgn0039800 Npc2g Niemann-Pick type C-2g http://flybase.net/reports/FBgn0039800.html FBgn0064875 protein_coding_gene 0032934=sterol binding "0015918=sterol transport, 0007498=mesoderm development, 0042381=hemolymph coagulation" 0005576=extracellular region "npc2g, CG11314, BcDNA:RE56164" "IPR014756=Immunoglobulin E-set, IPR003172=MD-2-related lipid-recognition domain" CG11314 16-Dec-15 2015_12 viable FBgn0030417 CG15725 http://flybase.net/reports/FBgn0030417.html protein_coding_gene 0046872=metal ion binding "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG15725 16-Dec-15 2015_12 viable FBgn0039830 ATPsynC "ATP synthase, subunit C" http://flybase.net/reports/FBgn0039830.html FBgn0027724 protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0015992=proton transport, 0015986=ATP synthesis coupled proton transport, 0015991=ATP hydrolysis coupled proton transport" "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "F0/F1 ATP synthase Lipid-binding protein, CG1746, AT91, ATP synthase lipid-binding protein, anon-EST:Posey224, ATP synthase Lipid-binding protein P1" "IPR002379=V-ATPase proteolipid subunit C-like domain, IPR020537=ATPase, F0 complex, subunit C, DCCD-binding site, IPR000454=ATPase, F0 complex, subunit C" CG1746 16-Dec-15 2015_12 "ENSDARG00000017775(zgc:55970),ENSDARG00000009447(atp5g),ENSDARG00000056008(zgc:73293),ENSDARG00000055846" Q0130(OLI1) WBGene00022336(Y82E9BR.3) "ENSXETG00000024423(atp5g3),ENSXETG00000016655(atp5g1)" "ENSMUSG00000062683(Atp5g2),ENSMUSG00000018770(Atp5g3),ENSMUSG00000006057(Atp5g1)" "ENSG00000135390(ATP5G2),ENSG00000154518(ATP5G3)" FBgn0011056 l(1)Q9 lethal (1) Q9 http://flybase.net/reports/FBgn0011056.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0034098 krimp krimper http://flybase.net/reports/FBgn0034098.html protein_coding_gene 0046872=metal ion binding "0007310=oocyte dorsal/ventral axis specification, 0007319=negative regulation of oskar mRNA translation, 0030717=karyosome formation" "0048471=perinuclear region of cytoplasm, 0043186=P granule" "Montecristo, KRIMP, Krimp, mtc, CG15707, Krimper, montecristo" "IPR000571=Zinc finger, CCCH-type, IPR002999=Tudor domain" CG15707 16-Dec-15 2015_12 "female semi-sterile,female sterile,recessive" "karyosome,chorion,chorion | germline clone" FBgn0032915 CG12050 http://flybase.net/reports/FBgn0032915.html protein_coding_gene 0009267=cellular response to starvation "IPR001680=WD40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR011044=Quinoprotein amine dehydrogenase, beta chain-like, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG12050 16-Dec-15 2015_12 ENSDARG00000040730(wdr75) ENSXETG00000009873(WDR75) ENSMUSG00000025995(Wdr75) ENSG00000115368(WDR75) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02151 I -1.897178203 -0.786246653 0.017748284 0.037476666 0.862965381 -0.38943408 FBgn0038642 Muc91C Mucin 91C http://flybase.net/reports/FBgn0038642.html protein_coding_gene 0005201=extracellular matrix structural constituent 0022008=neurogenesis 0031012=extracellular matrix "mucin 91C, Muc91C, Mucin 91C, CG7709" CG7709 16-Dec-15 2015_12 YJL041W(NSP1) ENSMUSG00000025272(Tro) "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC21696 I -0.525797613 2.030186698 -1.282301825 0.757747248 -0.242011862 -0.788227803 FBgn0034405 Jheh2 Juvenile hormone epoxide hydrolase 2 http://flybase.net/reports/FBgn0034405.html protein_coding_gene "0033961=cis-stilbene-oxide hydrolase activity, 0008096=juvenile hormone epoxide hydrolase activity, 0004301=epoxide hydrolase activity" 0006719=juvenile hormone catabolic process 0043231=intracellular membrane-bounded organelle "Juvenile Hormone esterase, DmEH, juvenile hormone epoxide hydrolase 2, CT34977, jheh2, CG15102" "IPR029058=Alpha/Beta hydrolase fold, IPR016292=Epoxide hydrolase, IPR010497=Epoxide hydrolase, N-terminal, IPR000639=Epoxide hydrolase-like" CG15102 16-Dec-15 2015_12 ENSDARG00000042854(ephx1) WBGene00020909(W01A11.1) ENSXETG00000022654(EPHX1) ENSMUSG00000038776(Ephx1) ENSG00000143819(EPHX1) viable FBgn0065622 l(2)SH0802 lethal (2) SH0802 http://flybase.net/reports/FBgn0065622.html gene l(2)SH2 0802 16-Dec-15 2015_12 "lethal,recessive" FBgn0038897 CG5849 http://flybase.net/reports/FBgn0038897.html protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR024571=ERAP1-like C-terminal domain, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase" CG5849 16-Dec-15 2015_12 viable FBgn0058253 CR40253 http://flybase.net/reports/FBgn0058253.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0026059 Mhcl Myosin heavy chain-like http://flybase.net/reports/FBgn0026059.html "FBgn0038399, FBgn0051045" protein_coding_gene "0000146=microfilament motor activity, 0005524=ATP binding, 0042623=ATPase activity, coupled, 0030898=actin-dependent ATPase activity, 0051015=actin filament binding" "0016459=myosin complex, 0030017=sarcomere" "myosin heavy chain, CG10224, myosin XVIII (PDZ), Myosin XVIII, MHCL(PDZ), myosin 18, PDZ-myosin, DmPDZ, Myosin-heavy-chain-like, CG31045, CG10218" "IPR001478=PDZ domain, IPR000048=IQ motif, EF-hand binding site, IPR001609=Myosin head, motor domain, IPR002928=Myosin tail, IPR031244=Unconventional myosin-XVIIIa, IPR027401=Myosin-like IQ motif-containing domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG31045 16-Dec-15 2015_12 ENSDARG00000061862(myo18l1) ENSXETG00000009454() ENSMUSG00000000631(Myo18a) ENSG00000196535(MYO18A) neuroanatomy defective "ventral nerve cord,peripheral nervous system" FBgn0053003 CG33003 http://flybase.net/reports/FBgn0053003.html protein_coding_gene CG33003 16-Dec-15 2015_12 FBgn0037284 CG14659 http://flybase.net/reports/FBgn0037284.html protein_coding_gene CG14659 16-Dec-15 2015_12 viable DRSC12245 I 1.507633067 0.412635702 1.013589177 1.30208749 -1.362482308 -0.878120672 FBgn0001281 janB janus B http://flybase.net/reports/FBgn0001281.html FBgn0051024 protein_coding_gene 0007548=sex differentiation "jan B, bs30f02.y1, CG31024, jan, janus, CG7931, Jan-B, Jan, janusB" IPR007702=Janus CG7931 16-Dec-15 2015_12 " spermatogenesis && adult stage , larval stage | third instar--adult stage | male " " spermatocyte

, organism

, testis | restricted

" pupal stage | late testis | restricted

viable FBgn0014298 l(3)64Bi lethal (3) 64Bi http://flybase.net/reports/FBgn0014298.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002311 l(3)85Ab lethal (3) 85Ab http://flybase.net/reports/FBgn0002311.html gene L2 16-Dec-15 2015_12 lethal FBgn0264541 CG43920 http://flybase.net/reports/FBgn0264541.html protein_coding_gene CR43920 CG43920 16-Dec-15 2015_12 FBgn0259433 C278 http://flybase.net/reports/FBgn0259433.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta,ectopic" FBgn0065705 l(2)SH0613 lethal (2) SH0613 http://flybase.net/reports/FBgn0065705.html gene l(2)SH2 0613 16-Dec-15 2015_12 "lethal,recessive" FBgn0001498 l(1)10Bl lethal (1) 10Bl http://flybase.net/reports/FBgn0001498.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022035 l(2)k08612 lethal (2) k08612 http://flybase.net/reports/FBgn0022035.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001265 inb incised balloon http://flybase.net/reports/FBgn0001265.html gene 16-Dec-15 2015_12 visible wing FBgn0026213 l(3)S027714 lethal (3) S027714 http://flybase.net/reports/FBgn0026213.html gene "l(3)027714, 0041/08, 0277/14" 16-Dec-15 2015_12 larval stage | third instar embryonic/larval proventriculus

"lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0039902 Zip102B Zinc/iron regulated transporter-related protein 102B http://flybase.net/reports/FBgn0039902.html protein_coding_gene 0046873=metal ion transmembrane transporter activity "0055085=transmembrane transport, 0030001=metal ion transport" 0016020=membrane "dZip102B, cg2177, CG2177" IPR003689=Zinc/iron permease CG2177 16-Dec-15 2015_12 ENSDARG00000070447(slc39a9) YOR079C(ATX2) WBGene00011329(T01D3.5) "ENSXETG00000017909(slc39a9),ENSXETG00000018648(BC096499.1)" ENSMUSG00000048833(Slc39a9) ENSG00000029364(SLC39A9) FBgn0000516 dw dwarf http://flybase.net/reports/FBgn0000516.html gene 16-Dec-15 2015_12 "visible,female sterile" FBgn0267750 CR46081 http://flybase.net/reports/FBgn0267750.html non_protein_coding_gene Mgn959 CR46081 16-Dec-15 2015_12 FBgn0005755 l(1)TK310 lethal (1) TK310 http://flybase.net/reports/FBgn0005755.html gene l310 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0266148 CR44854 http://flybase.net/reports/FBgn0266148.html non_protein_coding_gene lincRNA.136 CR44854 16-Dec-15 2015_12 FBgn0034413 CG15115 http://flybase.net/reports/FBgn0034413.html protein_coding_gene CG15115 16-Dec-15 2015_12 viable FBgn0038589 CG18598 http://flybase.net/reports/FBgn0038589.html protein_coding_gene CT42539 IPR025314=Domain of unknown function DUF4219 CG18598 16-Dec-15 2015_12 FBgn0032824 CG13962 http://flybase.net/reports/FBgn0032824.html protein_coding_gene CG13962 16-Dec-15 2015_12 viable FBgn0062649 EP417 EP417 http://flybase.net/reports/FBgn0062649.html gene EP(3)0417 16-Dec-15 2015_12 FBgn0262201 mir-973 mir-973 stem loop http://flybase.net/reports/FBgn0262201.html miRNA_gene "miR-973, dme-mir-973, 973, CR42908" CR42908 16-Dec-15 2015_12 viable FBgn0014983 l(2)46Cd lethal (2) 46Cd http://flybase.net/reports/FBgn0014983.html gene "433, IV, Group IV" 16-Dec-15 2015_12 lethal FBgn0005122 l(1)nd lethal no differentiation http://flybase.net/reports/FBgn0005122.html gene 16-Dec-15 2015_12 lethal imaginal disc primordium FBgn0259298 C503 http://flybase.net/reports/FBgn0259298.html gene 16-Dec-15 2015_12 visible "wing,wing margin" FBgn0005128 l(1)J1660 lethal (1) J1660 http://flybase.net/reports/FBgn0005128.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0013970 Gebf-I glue enhancer binding factor-I http://flybase.net/reports/FBgn0013970.html gene 0043565=sequence-specific DNA binding 0005634=nucleus GEBF-I 16-Dec-15 2015_12 FBgn0262721 CG43165 http://flybase.net/reports/FBgn0262721.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG43165 16-Dec-15 2015_12 FBgn0023086 eve::h eve::h http://flybase.net/reports/FBgn0023086.html engineered_fusion_gene 16-Dec-15 2015_12 "viable,partially,lethal,female limited" FBgn0036353 CG10171 http://flybase.net/reports/FBgn0036353.html protein_coding_gene 0016021=integral component of membrane "IPR002794=Protein of unknown function DUF92, TMEM19" CG10171 16-Dec-15 2015_12 ENSDARG00000035225(tmem19) ENSXETG00000011587(TMEM19) ENSMUSG00000069520(Tmem19) ENSG00000139291(TMEM19) viable FBgn0035735 Cpr65Ea Cuticular protein 65Ea http://flybase.net/reports/FBgn0035735.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr65Ea, CG8640" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8640 16-Dec-15 2015_12 viable FBgn0039528 dsd distracted http://flybase.net/reports/FBgn0039528.html protein_coding_gene 0008039=synaptic target recognition "Attractin, CT17798, CG5634" "IPR002049=Laminin EGF domain, IPR013032=EGF-like, conserved site, IPR000859=CUB domain, IPR016201=Plexin-like fold, IPR000742=EGF-like domain, IPR015915=Kelch-type beta propeller" CG5634 16-Dec-15 2015_12 ENSDARG00000006420(atrnl1) WBGene00006432(tag-53) "ENSXETG00000004357(ATRN),ENSXETG00000023806(ATRNL1)" "ENSMUSG00000027312(Atrn),ENSMUSG00000054843(Atrnl1)" "ENSG00000107518(ATRNL1),ENSG00000088812(ATRN)" viable FBgn0042180 CG18870 http://flybase.net/reports/FBgn0042180.html FBgn0027354 protein_coding_gene "anon-57Fa, unnamed" IPR002172=Low-density lipoprotein (LDL) receptor class A repeat CG18870 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0050051 CG30051 http://flybase.net/reports/FBgn0050051.html FBgn0043526 protein_coding_gene "anon-AE003822.1, unnamed" IPR026721=Transmembrane protein 18 CG30051 16-Dec-15 2015_12 ENSDARG00000036704(zgc:101011) ENSXETG00000027985(tmem18) ENSMUSG00000043061(Tmem18) ENSG00000151353(TMEM18) viable FBgn0003415 skd skuld http://flybase.net/reports/FBgn0003415.html "FBgn0024200, FBgn0024569, FBgn0024577, FBgn0037043, FBgn0041162" protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0004252=serine-type endopeptidase activity, 0005515=protein binding" "0007526=larval somatic muscle development, 0006357=regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0048749=compound eye development, 0030177=positive regulation of Wnt signaling pathway, 0006366=transcription from RNA polymerase II promoter, 0036011=imaginal disc-derived leg segmentation, 0006508=proteolysis, 0048190=wing disc dorsal/ventral pattern formation, 0022416=chaeta development, 0045498=sex comb development, 0045165=cell fate commitment" "0005654=nucleoplasm, 0070847=core mediator complex, 0016592=mediator complex, 0005634=nucleus" "TRAP240, dTRAP240, Skd, Skuld, dTrap240, dmMED13, pap, Suppressor of constitutively activated Dpp signaling 78, l(3)rK760, Med13, blind spot, Poils aux pattes, Skd/Pap/Bli, Pap/Trap, Trap240, dMED13, l(3)L7062, Mediator complex subunit 13, Srb9/AMIB/PAP/TRAP240, Skd/Med13, bli, bls, Scad78, CG9936, pap/dTRAP240, flytrap, LD28662, Pap, poils aux pattes, siren9, SPH203, MED13" "IPR009401=Mediator complex, subunit Med13, IPR021643=Mediator complex, subunit Med13, N-terminal, metazoa/fungi" CG9936 16-Dec-15 2015_12 "ENSDARG00000003910(LOC100149462),ENSDARG00000053884" WBGene00002295(let-19) "ENSXETG00000006581(MED13L),ENSXETG00000010728(MED13)" "ENSMUSG00000034297(Med13),ENSMUSG00000018076(Med13l)" "ENSG00000123066(MED13L),ENSG00000108510(MED13)" larval stage organism | ubiquitous

"lethal,viable,fertile,recessive,visible,dominant,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,somatic clone,partially lethal - majority die,some die during pupal stage" "crystal cell,mitotic cell cycle,adult abdomen,maternal effect,embryonic/larval mouth,sex comb,cell autonomous,ectopic,somatic clone,prothoracic leg,distal,maxillary palpus,eye disc,photoreceptor cell,antennal disc,wing disc,leg,somatic clone - Minute background,sex comb tooth,prothoracic tarsal segment,eye,mesothoracic bristle,wing margin,wing,mesothoracic tergum" DRSC11898 IEK -0.135743256 1.897175355 -2.380304117 1.886270415 2.746434393 3.319092141 FBgn0022965 snRNPF snRNPF http://flybase.net/reports/FBgn0022965.html gene "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" F 16-Dec-15 2015_12 FBgn0259274 EP-234 http://flybase.net/reports/FBgn0259274.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta" FBgn0060991 l(3)S027418 lethal (3) S027418 http://flybase.net/reports/FBgn0060991.html gene 0274/18 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0010700 l(2)s4831 lethal (2) s4831 http://flybase.net/reports/FBgn0010700.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" crystal cell FBgn0084688 tre-2 tre-2 http://flybase.net/reports/FBgn0084688.html "CR34648, CG34648" 16-Dec-15 2015_12 FBgn0035993 Nf-YA Nuclear factor Y-box A http://flybase.net/reports/FBgn0035993.html protein_coding_gene "0000976=transcription regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0051726=regulation of cell cycle, 0046331=lateral inhibition, 0045466=R7 cell differentiation, 0006909=phagocytosis, 0045893=positive regulation of transcription, DNA-templated" "0016602=CCAAT-binding factor complex, 0005634=nucleus" "NF-YA, CG3891, nuclear factor Y-box A, dNF-YA" "IPR001289=CCAAT-binding transcription factor, subunit B" CG3891 16-Dec-15 2015_12 "ENSDARG00000042004(nfya),ENSDARG00000001621(zgc:92567)" YGL237C(HAP2) WBGene00043056(nfya-2) ENSXETG00000011865(cbfb) ENSMUSG00000023994(Nfya) ENSG00000001167(NFYA) "lethal,partially lethal - majority die,visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during third instar larval stage,some die during larval stage" "chaeta,supernumerary,mesothoracic tergum,head | pharate adult stage,eye,ommatidium,antenna,ectopic,adult thorax" FBgn0046653 anon-38D.11 anon-38D.11 http://flybase.net/reports/FBgn0046653.html gene 38D.11 16-Dec-15 2015_12 FBgn0265420 CR44332 http://flybase.net/reports/FBgn0265420.html non_protein_coding_gene CR44332 16-Dec-15 2015_12 FBgn0060341 l(3)S144002 lethal (3) S144002 http://flybase.net/reports/FBgn0060341.html gene 1440/02 16-Dec-15 2015_12 FBgn0265414 CR44326 http://flybase.net/reports/FBgn0265414.html non_protein_coding_gene CR44326 16-Dec-15 2015_12 FBgn0046682 anon-38B.1 anon-38B.1 http://flybase.net/reports/FBgn0046682.html gene 38B.1 16-Dec-15 2015_12 FBgn0014233 l(2)31Ep lethal (2) 31Ep http://flybase.net/reports/FBgn0014233.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041094 scyl scylla http://flybase.net/reports/FBgn0041094.html "FBgn0036151, FBgn0062166" protein_coding_gene "0032504=multicellular organism reproduction, 0006974=cellular response to DNA damage stimulus, 0009968=negative regulation of signal transduction, 0008219=cell death, 0045926=negative regulation of growth, 0008258=head involution" 0005737=cytoplasm "scy, CG7590, scylla, Scylla, anon-WO0118547.215, 7590" IPR012918=RTP801-like CG7590 16-Dec-15 2015_12 ENSDARG00000037618(zgc:64114) "ENSMUSG00000046818(Ddit4l),ENSMUSG00000020108(Ddit4)" "ENSG00000168209(DDIT4),ENSG00000145358(DDIT4L)" "decreased cell size,somatic clone,small body,long lived,viable,fertile" FBgn0005091 fs(2)OWc3 female sterile (2) OWc3 http://flybase.net/reports/FBgn0005091.html gene 16-Dec-15 2015_12 FBgn0053299 CG33299 http://flybase.net/reports/FBgn0053299.html protein_coding_gene CG33299 16-Dec-15 2015_12 viable FBgn0037933 Ho Heme oxygenase http://flybase.net/reports/FBgn0037933.html protein_coding_gene 0004392=heme oxygenase (decyclizing) activity "0006788=heme oxidation, 0042168=heme metabolic process" 0012505=endomembrane system "CT34507, Haem oxygenase, DmHO, dHO, HO, heme oxygenase, CG14716" "IPR002051=Haem oxygenase, IPR016053=Haem oxygenase-like, IPR016084=Haem oxygenase-like, multi-helical" CG14716 16-Dec-15 2015_12 YLR205C(HMX1) "ENSMUSG00000004070(Hmox2),ENSMUSG00000005413(Hmox1)" "ENSG00000103415(HMOX2),ENSG00000100292(HMOX1)" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "eye,eye disc,temperature conditional" FBgn0043543 anon-AE003534.1 anon-AE003534.1 http://flybase.net/reports/FBgn0043543.html gene unnamed 16-Dec-15 2015_12 FBgn0016803 l(1)K5 lethal (1) K5 http://flybase.net/reports/FBgn0016803.html gene K5 16-Dec-15 2015_12 "lethal,recessive" FBgn0086663 snoRNA:ë¬18S-1275 snoRNA:ë¬18S-1275 http://flybase.net/reports/FBgn0086663.html "FBgn0065050, FBgn0083056, FBgn0053625" snoRNA_gene 0005730=nucleolus "Dm-783, snoRNA:783, CR33625, Psi 18S-1275(SnoR783), psi18s-1275, snoR783" CR33625 16-Dec-15 2015_12 FBgn0029639 CG14419 http://flybase.net/reports/FBgn0029639.html protein_coding_gene CG14419 16-Dec-15 2015_12 FBgn0067350 l(3)95Eb lethal (3) 95Eb http://flybase.net/reports/FBgn0067350.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034394 CG15096 http://flybase.net/reports/FBgn0034394.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane CT42567 "IPR011701=Major facilitator superfamily, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG15096 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,fertile" FBgn0264413 FCE-F http://flybase.net/reports/FBgn0264413.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0069154 mcl(3)Z2761 mcl(3)Z2761 http://flybase.net/reports/FBgn0069154.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0035724 CG10064 http://flybase.net/reports/FBgn0035724.html protein_coding_gene "IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site" CG10064 16-Dec-15 2015_12 ENSDARG00000041321(wdr16) ENSXETG00000019539(WDR16) ENSMUSG00000020904(Wdr16) ENSG00000166596(WDR16) viable FBgn0065473 l(2)SH1315 lethal (2) SH1315 http://flybase.net/reports/FBgn0065473.html gene l(2)SH2 1315 16-Dec-15 2015_12 "lethal,recessive" FBgn0086242 Pla2 Phospholipase A2 http://flybase.net/reports/FBgn0086242.html gene "pla2, phospholipase A[[2]], phospholipase A2, PLA[[2]]" 16-Dec-15 2015_12 FBgn0034683 CG13500 http://flybase.net/reports/FBgn0034683.html protein_coding_gene CG13500 16-Dec-15 2015_12 viable FBgn0266993 CR45444 http://flybase.net/reports/FBgn0266993.html non_protein_coding_gene CR45444 16-Dec-15 2015_12 FBgn0085628 CG41347 http://flybase.net/reports/FBgn0085628.html FBan0041347 protein_coding_gene 16-Dec-15 2015_12 FBgn0040878 CG15911 http://flybase.net/reports/FBgn0040878.html protein_coding_gene 16-Dec-15 2015_12 FBgn0041702 CG15107 http://flybase.net/reports/FBgn0041702.html protein_coding_gene IPR028002=Myb/SANT-like DNA-binding domain CG15107 16-Dec-15 2015_12 "viable,fertile" FBgn0265191 Glycogenin Glycogenin http://flybase.net/reports/FBgn0265191.html "FBgn0034603, FBgn0045283, FBgn0265179" protein_coding_gene 0008466=glycogenin glucosyltransferase activity 0005978=glycogen biosynthetic process 0005829=cytosol "CG9480, CG44244, NEST:bs16a02" "IPR002495=Glycosyl transferase, family 8, IPR029044=Nucleotide-diphospho-sugar transferases" CG44244 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0011650 Mads-2 Mads-2 http://flybase.net/reports/FBgn0011650.html gene 16-Dec-15 2015_12 FBgn0001049 Fs(3)Hod Female sterile (3) Hodos http://flybase.net/reports/FBgn0001049.html gene 0007344=pronuclear fusion "Hod, Fs(3)Sz10, Fs(3)Hodos" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus | maternal effect,female pronucleus | maternal effect" FBgn0010223 Gë±f G protein ë± f subunit http://flybase.net/reports/FBgn0010223.html protein_coding_gene "0004871=signal transducer activity, 0031683=G-protein beta/gamma-subunit complex binding, 0001664=G-protein coupled receptor binding, 0019001=guanyl nucleotide binding, 0003924=GTPase activity" "0051489=regulation of filopodium assembly, 0007186=G-protein coupled receptor signaling pathway, 0007191=adenylate cyclase-activating dopamine receptor signaling pathway, 0035208=positive regulation of hemocyte proliferation, 0007606=sensory perception of chemical stimulus, 0007498=mesoderm development" "0005834=heterotrimeric G-protein complex, 0031234=extrinsic component of cytoplasmic side of plasma membrane" "Gf, G[[f]], Galpha[[f]]73B, Gf alpha, GTP-binding protein alpha-subunit, CG12232, Galpha73B, G protein alpha 73B, Gfalpha" "IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011025=G protein alpha subunit, helical insertion" CG12232 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage " " nurse cell

, oocyte

, amnioserosa

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, gastric caecum

" "partially lethal,viable,fertile" "embryonic/larval hemocyte,filopodium" FBgn0031026 CG12231 http://flybase.net/reports/FBgn0031026.html protein_coding_gene IPR008580=PPPDE putative peptidase domain CG12231 16-Dec-15 2015_12 viable FBgn0011107 l(1)Q68 lethal (1) Q68 http://flybase.net/reports/FBgn0011107.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0033085 CG15908 http://flybase.net/reports/FBgn0033085.html protein_coding_gene IPR021475=Protein of unknown function DUF3128 CG15908 16-Dec-15 2015_12 ENSDARG00000069468(si:ch211-51h9.6) ENSMUSG00000071632(2510002D24Rik) ENSG00000185065 viable FBgn0260376 GSd468 http://flybase.net/reports/FBgn0260376.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0011127 l(1)Q201 lethal (1) Q201 http://flybase.net/reports/FBgn0011127.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0060340 l(3)S144201b lethal (3) S144201b http://flybase.net/reports/FBgn0060340.html gene 1442/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0052720 CG32720 http://flybase.net/reports/FBgn0052720.html FBgn0045438 protein_coding_gene NEST:bs01f06 CG32720 16-Dec-15 2015_12 FBgn0036595 CG13046 http://flybase.net/reports/FBgn0036595.html protein_coding_gene CG13046 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0016886 l(2)39DEk lethal (2) 39DEk http://flybase.net/reports/FBgn0016886.html gene D282 16-Dec-15 2015_12 lethal FBgn0278598 CR46268 http://flybase.net/reports/FBgn0278598.html non_protein_coding_gene CR46268 16-Dec-15 2015_12 FBgn0001524 l(1)11Dc lethal (1) 11Dc http://flybase.net/reports/FBgn0001524.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0083121 Uhg7 Uhg7 http://flybase.net/reports/FBgn0083121.html FBgn0259930 non_protein_coding_gene "CR42453, dUHG7, dUhg7, dUhg-like 7" CR42453 16-Dec-15 2015_12 FBgn0051973 Cda5 Chitin deacetylase-like 5 http://flybase.net/reports/FBgn0051973.html "FBgn0031210, FBgn0031211, FBgn0063656" protein_coding_gene "0008061=chitin binding, 0016810=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds" "0005975=carbohydrate metabolic process, 0006030=chitin metabolic process" 0005576=extracellular region "DmCDA5, BcDNA:RH43162, CG31973, CG2761, CG2776" "IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002509=NodB homology domain, IPR002557=Chitin binding domain" CG31973 16-Dec-15 2015_12 WBGene00002983(lgx-1) "viable,fertile" DRSC21330 IEK 1.719152867 -1.655016048 0.938005562 1.794342424 1.899090472 0.201780002 FBgn0013705 mt:tRNA:S:AGY mitochondrial serine AGY tRNA http://flybase.net/reports/FBgn0013705.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "tRNA[Ser], tRNA[Ser]AGY, mtdbD00006305, CR34080, mt-tRNA[Ser] (GCU), tRNA[Ser]GCU" CR34080 16-Dec-15 2015_12 FBgn0085344 CG34315 http://flybase.net/reports/FBgn0085344.html protein_coding_gene CG34315 16-Dec-15 2015_12 FBgn0043034 l(2)42Ca lethal (2) 42Ca http://flybase.net/reports/FBgn0043034.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029867 CG3847 http://flybase.net/reports/FBgn0029867.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG3847 16-Dec-15 2015_12 DRSC18327 I -1.692950441 0.173307437 -0.377675886 1.000185728 0.168212147 1.178618953 FBgn0014375 popeye popeye http://flybase.net/reports/FBgn0014375.html gene 16-Dec-15 2015_12 FBgn0035685 CG13297 http://flybase.net/reports/FBgn0035685.html FBgn0062982 protein_coding_gene BcDNA:RE64858 CG13297 16-Dec-15 2015_12 viable FBgn0031208 CG11023 http://flybase.net/reports/FBgn0031208.html protein_coding_gene 0016929=SUMO-specific protease activity 0016926=protein desumoylation "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG11023 16-Dec-15 2015_12 "ENSDARG00000068450(senp3a),ENSDARG00000056741(senp3b)" YPL020C(ULP1) "ENSMUSG00000067716(Gm5415),ENSMUSG00000049830(Gm9839),ENSMUSG00000058176" "ENSG00000161956(SENP3),ENSG00000079387(SENP1)" FBgn0051804 CG31804 http://flybase.net/reports/FBgn0051804.html "FBgn0045098, FBgn0045160, FBgn0045312, FBgn0045324" protein_coding_gene "NEST:bs13h04, NEST:bs34f07, NEST:bs12c10, NEST:bs27h11" CG31804 16-Dec-15 2015_12 FBgn0264574 Glut1 Glucose transporter 1 http://flybase.net/reports/FBgn0264574.html "FBgn0261914, FBgn0025593, FBgn0028221, FBgn0035178" protein_coding_gene 0005355=glucose transmembrane transporter activity "0055085=transmembrane transport, 0090277=positive regulation of peptide hormone secretion" 0016021=integral component of membrane "Dmglut1, CG13908, l(3)61Ea, GLU, CG43946, lethal (3) S007412, Glu T1, l(3)S007412, CG1086, glucose transporter, DmGLUT1, Glt1, glut1, Glut-1, 0074/12, glucose transporter 1, l(3)L1H, DmGluT1" "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR003663=Sugar/inositol transporter" CG43946 16-Dec-15 2015_12 "ENSDARG00000013295(slc2a3),ENSDARG00000037861,ENSDARG00000001437(slc2a1a),ENSDARG00000007412(slc2a1b),ENSDARG00000056196(slc2a2),ENSDARG00000001937(LOC100334818)" YNL318C(HXT14) "WBGene00019207(H17B01.1),WBGene00019979(R09B5.11)" "ENSXETG00000023902(),ENSXETG00000017639(SLC2A1),ENSXETG00000009145(slc2a2)" "ENSMUSG00000028645(Slc2a1),ENSMUSG00000018566(Slc2a4),ENSMUSG00000003153(Slc2a3),ENSMUSG00000027690(Slc2a2),ENSMUSG00000028976(Slc2a5)" "ENSG00000117394(SLC2A1),ENSG00000181856(SLC2A4),ENSG00000059804(SLC2A3),ENSG00000173262(SLC2A14),ENSG00000163581(SLC2A2),ENSG00000142583(SLC2A5)" FBgn0261065 Cpsf73 Cleavage and polyadenylation specificity factor 73 http://flybase.net/reports/FBgn0261065.html "FBgn0066368, FBgn0038636" protein_coding_gene 0003677=DNA binding "0006398=histone mRNA 3'-end processing, 0006379=mRNA cleavage, 0022008=neurogenesis, 0006378=mRNA polyadenylation" 0005847=mRNA cleavage and polyadenylation specificity factor complex "cleavage and polyadenylation specificity factor, 73kD-subunit, CG7698, CPSF-73, CPSF73, dCPSF-73, cpsf-73" "IPR001279=Metallo-beta-lactamase, IPR011108=RNA-metabolising metallo-beta-lactamase, IPR021718=Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term, IPR022712=Beta-Casp domain" CG7698 16-Dec-15 2015_12 ENSDARG00000027649(cpsf3) YLR277C(YSH1) WBGene00013460(cpsf-3) ENSXETG00000008263(cpsf3) ENSMUSG00000054309(Cpsf3) ENSG00000119203(CPSF3) DRSC16291 E 0.471566024 -0.003234465 1.518107582 -0.405623021 -0.418749736 -0.676282221 FBgn0025595 AkhR Adipokinetic hormone receptor http://flybase.net/reports/FBgn0025595.html FBgn0043817 protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity, 0097003=adipokinetic hormone receptor activity, 0097004=adipokinetic hormone binding" "0070328=triglyceride homeostasis, 0016042=lipid catabolic process, 0055088=lipid homeostasis, 0033500=carbohydrate homeostasis, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "Gonadotropin-releasing hormone receptor, GRHR, AKHR, akhr, gonadotropin-releasing hormone receptor, Akhr, GRHR/CG11325, Drm-AKH receptor-1, DAKHR-1, BEST:GH19447, unnamed, DGRHR, Adipokinetic Hormone Receptor, GnRHR, adipokinetic hormone receptor, gonadotrophin-releasing hormone receptor, DAKHR, hormone receptor, AKH receptor, CG11325" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG11325 16-Dec-15 2015_12 "ENSDARG00000041866,ENSDARG00000038116(gnrhr4)" WBGene00018798(gnrr-1) "ENSXETG00000016612(GNRHR2),ENSXETG00000017726()" ENSMUSG00000029255(Gnrhr) "ENSG00000109163(GNRHR),ENSG00000211451" "viable,fertile,stress response defective" "lipid particle,adult fat body,embryonic/larval midgut" FBgn0023494 Maupiti Maupiti http://flybase.net/reports/FBgn0023494.html region 16-Dec-15 2015_12 FBgn0053393 5SrRNA:CR33393 5SrRNA:CR33393 http://flybase.net/reports/FBgn0053393.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33393 CR33393 16-Dec-15 2015_12 FBgn0065303 l(2)SH1977 lethal (2) SH1977 http://flybase.net/reports/FBgn0065303.html gene l(2)SH2 1977 16-Dec-15 2015_12 "lethal,recessive" FBgn0021907 l(2)k11702 lethal (2) k11702 http://flybase.net/reports/FBgn0021907.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0264389 opm opossum http://flybase.net/reports/FBgn0264389.html "FBgn0259125, FBgn0030606" protein_coding_gene 0005215=transporter activity "0048042=regulation of post-mating oviposition, 0022008=neurogenesis, 0000003=reproduction, 0061357=positive regulation of Wnt protein secretion, 0048193=Golgi vesicle transport, 0090263=positive regulation of canonical Wnt signaling pathway" "0016021=integral component of membrane, 0005783=endoplasmic reticulum" "opo, Opossum, p24, CG9053" "IPR009038=GOLD domain, IPR015720=TMP21-related" CG9053 16-Dec-15 2015_12 "ENSDARG00000008765(tmed5),ENSDARG00000031325(tmed1a),ENSDARG00000017255(tmed1b)" "YAL007C(ERP2),YOR016C(ERP4)" WBGene00010670(K08E4.6) "ENSXETG00000023000(tmed5),ENSXETG00000001321(),ENSXETG00000002260(tmed1)" "ENSMUSG00000063406(Tmed5),ENSMUSG00000032180(Tmed1)" "ENSG00000117500(TMED5),ENSG00000099203(TMED1)" DRSC22135 IEK 1.187507653 1.776691718 1.981034054 0.690165731 0.832875937 1.967223728 FBgn0058298 CG40298 http://flybase.net/reports/FBgn0058298.html FBan0040298 protein_coding_gene CG40298 16-Dec-15 2015_12 DRSC22274 IE 0.301637306 1.772498418 0.201109496 1.593466778 1.164481439 0.195856927 FBgn0053658 CG33658 http://flybase.net/reports/FBgn0053658.html FBgn0082850 protein_coding_gene "unnamed, BP1056" IPR010512=Protein of unknown function DUF1091 CG33658 16-Dec-15 2015_12 FBgn0001677 l(1)EN15 lethal (1) from Eugene Nonautonomous 15 http://flybase.net/reports/FBgn0001677.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264376 CR43828 http://flybase.net/reports/FBgn0264376.html non_protein_coding_gene CR43828 16-Dec-15 2015_12 FBgn0024219 ird9 immune response deficient 9 http://flybase.net/reports/FBgn0024219.html gene 0006963=positive regulation of antibacterial peptide biosynthetic process ird 16-Dec-15 2015_12 "viable,immune response defective,recessive,melanotic mass phenotype" melanotic mass FBgn0024183 vig vasa intronic gene http://flybase.net/reports/FBgn0024183.html protein_coding_gene 0003729=mRNA binding "0070828=heterochromatin organization, 0016246=RNA interference" "0016442=RISC complex, 0005703=polytene chromosome puff, 0005700=polytene chromosome, 0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" "BG:DS00929.13, VIG, EP(2)0812, Vasa intronic gene, unnamed, CG4170, Vig" IPR006861=Hyaluronan/mRNA-binding protein CG4170 16-Dec-15 2015_12 "ENSDARG00000003474,ENSDARG00000069400,ENSDARG00000025174(zgc:103482)" WBGene00006924(vig-1) "ENSXETG00000012394(pairbp1),ENSXETG00000014841(habp4)" "ENSMUSG00000036371(Serbp1),ENSMUSG00000021476(Habp4)" "ENSG00000142864(SERBP1),ENSG00000130956(HABP4)" "viable,fertile,female sterile,suppressor of variegation,dominant" embryonic/larval salivary gland FBgn0035370 Non2 Novel nucleolar protein 2 http://flybase.net/reports/FBgn0035370.html protein_coding_gene 0003677=DNA binding 0090307=mitotic spindle assembly 0005730=nucleolus "CG1240, Non2" "IPR014876=DEK, C-terminal, IPR003121=SWIB/MDM2 domain, IPR009057=Homeodomain-like" CG1240 16-Dec-15 2015_12 WBGene00020779(T24G10.2) "viable,visible,lethal" trichogen cell FBgn0000452 dil dilute http://flybase.net/reports/FBgn0000452.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0265182 CG44247 http://flybase.net/reports/FBgn0265182.html "FBgn0050420, FBgn0035074, FBgn0015562" protein_coding_gene 0016021=integral component of membrane "CG3749, CG30420" IPR009635=Neural proliferation differentiation control-1 CG44247 16-Dec-15 2015_12 viable FBgn0264726 CR43994 http://flybase.net/reports/FBgn0264726.html non_protein_coding_gene CR43994 16-Dec-15 2015_12 FBgn0260614 2L883 http://flybase.net/reports/FBgn0260614.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 viable "dorsal air sac primordium,somatic clone" FBgn0265985 CR44764 http://flybase.net/reports/FBgn0265985.html non_protein_coding_gene lincRNA.377 CR44764 16-Dec-15 2015_12 FBgn0034651 CG15676 http://flybase.net/reports/FBgn0034651.html protein_coding_gene 0051087=chaperone binding 0006457=protein folding 0016272=prefoldin complex "IPR009053=Prefoldin, IPR004127=Prefoldin alpha-like, IPR016655=Prefoldin subunit 3" CG15676 16-Dec-15 2015_12 viable DRSC27015 K 0.313234376 -0.247144738 -0.25080294 -0.185405363 1.969298654 1.080663229 FBgn0061041 l(3)S023809 lethal (3) S023809 http://flybase.net/reports/FBgn0061041.html gene 0238/09 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" FBgn0039430 CG5455 http://flybase.net/reports/FBgn0039430.html protein_coding_gene CT17296 IPR029058=Alpha/Beta hydrolase fold CG5455 16-Dec-15 2015_12 "viable,fertile" FBgn0052479 Usp10 Ubiquitin specific protease 10 http://flybase.net/reports/FBgn0052479.html "FBgn0035172, FBgn0035174" protein_coding_gene 0004843=ubiquitin-specific protease activity "0045747=positive regulation of Notch signaling pathway, 0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" 0005829=cytosol "CG13903, CG12503, CG32479, Q9W0L7" "IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG32479 16-Dec-15 2015_12 YER151C(UBP3) "visible,lethal,viable,fertile" "scutellar bristle,wing,supernumerary" FBgn0262371 mir-263b mir-263b stem loop http://flybase.net/reports/FBgn0262371.html "FBgn0067721, FBgn0262179" miRNA_gene "0022416=chaeta development, 0035195=gene silencing by miRNA, 0001745=compound eye morphogenesis, 0043066=negative regulation of apoptotic process" "CR42886, miR-263, CR33581, dme-miR-263b, mir-263b, miR-263b, dme-mir-263b" CR42886 16-Dec-15 2015_12 "visible,lethal" "eye,wing,wing vein,wing margin,interommatidial bristle" FBgn0051815 CG31815 http://flybase.net/reports/FBgn0051815.html protein_coding_gene CG31815 16-Dec-15 2015_12 "viable,fertile" FBgn0002098 l(2)57Cd lethal (2) 57Cd http://flybase.net/reports/FBgn0002098.html gene 16-Dec-15 2015_12 lethal FBgn0085583 CG41258 http://flybase.net/reports/FBgn0085583.html FBan0041258 protein_coding_gene 16-Dec-15 2015_12 FBgn0004742 l(3)85Di lethal (3) 85Di http://flybase.net/reports/FBgn0004742.html gene 16-Dec-15 2015_12 lethal FBgn0028609 l(2)W16 lethal (2) W16 http://flybase.net/reports/FBgn0028609.html gene l(2R)W16 16-Dec-15 2015_12 "lethal,recessive" FBgn0015981 l(2)PC4-G lethal (2) PC4-G http://flybase.net/reports/FBgn0015981.html gene l(2)PC4-J 16-Dec-15 2015_12 "lethal,recessive" FBgn0033754 Ak6 Adenylate kinase 6 http://flybase.net/reports/FBgn0033754.html protein_coding_gene "0005524=ATP binding, 0004017=adenylate kinase activity" 0009267=cellular response to starvation 0005634=nucleus "CG8816, DAK6" "IPR020618=Adenylate kinase isoenzyme 6, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8816 16-Dec-15 2015_12 ENSDARG00000035573(zgc:86811) YDL166C(FAP7) WBGene00008458(E02H1.6) ENSXETG00000018174(TTpA012f06.1) ENSMUSG00000078941 ENSG00000185057 viable FBgn0061207 MS101a MS101a http://flybase.net/reports/FBgn0061207.html gene 0004364=glutathione transferase activity "gst-3,2" 16-Dec-15 2015_12 chemical sensitive FBgn0026751 XRCC1 XRCC1 http://flybase.net/reports/FBgn0026751.html protein_coding_gene 0003684=damaged DNA binding "0006289=nucleotide-excision repair, 0006974=cellular response to DNA damage stimulus, 0046331=lateral inhibition, 0006285=base-excision repair, AP site formation, 0000012=single strand break repair" 0005634=nucleus "4208, Xrcc1, CG4208" "IPR002706=DNA-repair protein Xrcc1, N-terminal, IPR001357=BRCT domain, IPR008979=Galactose-binding domain-like" CG4208 16-Dec-15 2015_12 ENSDARG00000009494 ENSXETG00000015128(XRCC1) ENSMUSG00000051768(Xrcc1) ENSG00000073050(XRCC1) "viable,fertile,visible" "chaeta,trichogen cell" FBgn0261845 pre-mod(mdg4)-U http://flybase.net/reports/FBgn0261845.html protein_coding_gene CG42777 "IPR007588=Zinc finger, FLYWCH-type" CG42777 16-Dec-15 2015_12 FBgn0010741 l(3)01239 lethal (3) 01239 http://flybase.net/reports/FBgn0010741.html "FBgn0011417, FBgn0036123" protein_coding_gene "0051087=chaperone binding, 0051082=unfolded protein binding" "0006458='de novo' protein folding, 0006457=protein folding, 0048477=oogenesis, 0006909=phagocytosis" 0016272=prefoldin complex "CG6302, l(3)j9B4, P01239" "IPR009053=Prefoldin, IPR002777=Prefoldin beta-like, IPR027235=Prefoldin subunit 2" CG6302 16-Dec-15 2015_12 ENSDARG00000025391(pfdn2) YEL003W(GIM4) WBGene00019220(pfd-2) ENSXETG00000012702(PFDN2) ENSMUSG00000006412(Pfdn2) ENSG00000143256(PFDN2) "lethal,recessive,female sterile,visible,partially lethal - majority die,some die during pupal stage" "ovariole,germline clone,oocyte,embryonic/larval brain,trichogen cell" FBgn0083262 E(smoDN)786 Enhancer of smoDN 786 http://flybase.net/reports/FBgn0083262.html gene 16-Dec-15 2015_12 FBgn0035490 CG1136 http://flybase.net/reports/FBgn0035490.html protein_coding_gene 0042302=structural constituent of cuticle novel IPR000618=Insect cuticle protein CG1136 16-Dec-15 2015_12 viable FBgn0038416 CG17930 http://flybase.net/reports/FBgn0038416.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG17930 16-Dec-15 2015_12 viable FBgn0039064 CG4467 http://flybase.net/reports/FBgn0039064.html "FBan0004467, FBan0013825, FBgn0040592" protein_coding_gene "0008270=zinc ion binding, 0008237=metallopeptidase activity, 0004177=aminopeptidase activity" 0006508=proteolysis CG13825 "IPR024571=ERAP1-like C-terminal domain, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG4467 16-Dec-15 2015_12 viable DRSC14675 E 0.228041432 0.275159701 1.591409726 0.111235047 0.29627186 -0.43312686 FBgn0053877 His4:CG33877 His4:CG33877 http://flybase.net/reports/FBgn0053877.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33877 "IPR001951=Histone H4, IPR019809=Histone H4, conserved site, IPR009072=Histone-fold" CG33877 16-Dec-15 2015_12 "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) FBgn0010939 l(3)10112 lethal (3) 10112 http://flybase.net/reports/FBgn0010939.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262819 CG43190 http://flybase.net/reports/FBgn0262819.html protein_coding_gene DMG8-chr2R.14.008 CG43190 16-Dec-15 2015_12 FBgn0038142 CheA87a Chemosensory protein A 87a http://flybase.net/reports/FBgn0038142.html protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG14379, CheA87a" "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG14379 16-Dec-15 2015_12 viable FBgn0264379 CR43831 http://flybase.net/reports/FBgn0264379.html non_protein_coding_gene CR43831 16-Dec-15 2015_12 FBgn0014427 CG11899 http://flybase.net/reports/FBgn0014427.html FBgn0039649 protein_coding_gene 0004648=O-phospho-L-serine:2-oxoglutarate aminotransferase activity "0006564=L-serine biosynthetic process, 0008615=pyridoxine biosynthetic process" "anon-sts29, 39C10S, Ov8, ESTS:39C10S" "IPR020578=Aminotransferase class-V, pyridoxal-phosphate binding site, IPR000192=Aminotransferase class V domain, IPR022278=Phosphoserine aminotransferase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase" CG11899 16-Dec-15 2015_12 ENSDARG00000016733(psat1) YOR184W(SER1) WBGene00009177(F26H9.5) ENSXETG00000003623(psat) ENSMUSG00000024640(Psat1) ENSG00000135069(PSAT1) viable FBgn0027109 NPF neuropeptide F http://flybase.net/reports/FBgn0027109.html protein_coding_gene "0071859=neuropeptide F receptor binding, 0005184=neuropeptide hormone activity" "0035176=social behavior, 0007623=circadian rhythm, 0007186=G-protein coupled receptor signaling pathway, 0032095=regulation of response to food, 0045475=locomotor rhythm, 0048512=circadian behavior, 0035177=larval foraging behavior, 0030536=larval feeding behavior, 0008049=male courtship behavior, 0008345=larval locomotory behavior, 0007218=neuropeptide signaling pathway" 0005576=extracellular region "npf, DmNPF, Neuropeptide F, Neuropeptide F 1, dNPF, NPF89D3, NP-PP, Dm-NPF, NPF, neuropeptide-F, long neuropeptide F, Npf, Drm-NPF, NPY-like neuropeptide F, NPF-A2, CG10342, NPF-A1, neuropeptide F, dnpf" CG10342 16-Dec-15 2015_12 "behavior defective,developmental rate defective,conditional,chemical sensitive,feeding behavior defective,viable" FBgn0027599 CG2790 http://flybase.net/reports/FBgn0027599.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" BcDNA:GH03108 "IPR022755=Zinc finger, double-stranded RNA binding, IPR018253=DnaJ domain, conserved site, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR001623=DnaJ domain, IPR003604=Zinc finger, U1-type" CG2790 16-Dec-15 2015_12 ENSDARG00000057080 YNL227C(JJJ1) WBGene00001035(dnj-17) "ENSXETG00000000706(),ENSXETG00000003007()" ENSG00000168724(DNAJC21) "viable,visible" trichogen cell FBgn0020414 Idgf3 Imaginal disc growth factor 3 http://flybase.net/reports/FBgn0020414.html protein_coding_gene "0004568=chitinase activity, 0008084=imaginal disc growth factor receptor binding" "0005975=carbohydrate metabolic process, 0007444=imaginal disc development, 0006032=chitin catabolic process" 0005576=extracellular region "lincRNA.163, IDGF3, DmIDGF3, IDGF-3, idgf3, BG:DS02780.2, CG4559, imaginal disc growth factor 3, IDGF" "IPR029070=Chitinase insertion domain, IPR017853=Glycoside hydrolase superfamily, IPR015520=Imaginal disc growth factor, IPR011583=Chitinase II, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain" CG4559 16-Dec-15 2015_12 " larval stage | third instar , adult stage && oogenesis stage , embryonic stage , embryonic stage && larval stage " " ring gland

, oocyte

, amnioproctodeal invagination | vicinity of

, embryonic/larval tracheal system

, ventral furrow | vicinity of

, embryonic/larval fat body

, nurse cell

, imaginal disc

, larval optic lobe

, yolk

, embryonic/larval salivary gland

, larval brain

, cephalic furrow | vicinity of

, lymph gland

" viable FBgn0064766 CG7600 http://flybase.net/reports/FBgn0064766.html FBgn0027531 protein_coding_gene "IPR028091=FAM91, N-terminal domain, IPR028097=FAM91, C-terminal domain" CG7600 16-Dec-15 2015_12 ENSDARG00000003320(fam91a1) WBGene00009366(F33H2.2) ENSXETG00000023243(FAM91A1) ENSMUSG00000037119(D15Ertd621e) ENSG00000176853(FAM91A1) viable FBgn0259547 GG01546 http://flybase.net/reports/FBgn0259547.html gene 16-Dec-15 2015_12 visible wing FBgn0021977 l(2)k09923 lethal (2) k09923 http://flybase.net/reports/FBgn0021977.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0000922 fs(1)ne9 female sterile (1) no eggs 9 http://flybase.net/reports/FBgn0000922.html gene "ne9, fs(1)ne[9]" 16-Dec-15 2015_12 "female sterile germline-dependent,recessive,female sterile" "dorsal appendage,chorion,endochorion,oocyte" FBgn0040926 CG15334 http://flybase.net/reports/FBgn0040926.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019875 anon-92Da anon-92Da http://flybase.net/reports/FBgn0019875.html gene unnamed 16-Dec-15 2015_12 "visible,lethal,partially lethal - majority die" eye FBgn0010353 Nc94B Neural conserved at 94B http://flybase.net/reports/FBgn0010353.html gene nPKC 16-Dec-15 2015_12 FBgn0051741 CG31741 http://flybase.net/reports/FBgn0051741.html FBgn0032662 protein_coding_gene 0005044=scavenger receptor activity "0007155=cell adhesion, 0006952=defense response" "0005887=integral component of plasma membrane, 0016020=membrane" CG5750 IPR002159=CD36 antigen CG31741 16-Dec-15 2015_12 ENSXETG00000001195(SCARB1) viable FBgn0025558 CG4101 http://flybase.net/reports/FBgn0025558.html protein_coding_gene 0016021=integral component of membrane "unnamed, anon73B1, anon-73B1" IPR009621=Uncharacterised protein family UPF0239 CG4101 16-Dec-15 2015_12 viable FBgn0030808 RhoGAP15B Rho GTPase activating protein at 15B http://flybase.net/reports/FBgn0030808.html protein_coding_gene 0005096=GTPase activator activity "0043087=regulation of GTPase activity, 0043547=positive regulation of GTPase activity, 0007480=imaginal disc-derived leg morphogenesis" 0005794=Golgi apparatus "CG4937, gap20, RhoGAP15B" "IPR008936=Rho GTPase activation protein, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain, IPR029071=Ubiquitin-related domain, IPR000198=Rho GTPase-activating protein domain" CG4937 16-Dec-15 2015_12 WBGene00017760(F23H11.4) ENSXETG00000008629(SYDE2) "ENSMUSG00000032812(Arap1),ENSMUSG00000037999(Arap2),ENSMUSG00000024451(Arap3)" "ENSG00000047365(ARAP2),ENSG00000186635(ARAP1),ENSG00000120318(ARAP3)" partially lethal - majority die FBgn0005532 l(2)57Df lethal (2) 57Df http://flybase.net/reports/FBgn0005532.html gene 16-Dec-15 2015_12 lethal FBgn0262872 milt milton http://flybase.net/reports/FBgn0262872.html "FBgn0022201, FBgn0031884, FBgn0045937, FBgn0051630" protein_coding_gene "0019895=kinesin-associated mitochondrial adaptor activity, 0017022=myosin binding" "0048311=mitochondrion distribution, 0030382=sperm mitochondrion organization, 0019896=axon transport of mitochondrion, 0007287=Nebenkern assembly" 0005739=mitochondrion "anon-WO0153538.19, CG13777, CG43227, CG31630, Milton, l(2)k04704" "IPR022154=Trafficking kinesin-binding protein domain, IPR006933=HAP1, N-terminal" CG43227 16-Dec-15 2015_12 ENSDARG00000041304 "ENSXETG00000013857(TRAK1),ENSXETG00000012489()" "ENSMUSG00000032536(Trak1),ENSMUSG00000026028(Trak2)" "ENSG00000182606(TRAK1),ENSG00000115993(TRAK2)" FBgn0063437 ferm ferm http://flybase.net/reports/FBgn0063437.html gene 16-Dec-15 2015_12 FBgn0066101 LpR1 Lipophorin receptor 1 http://flybase.net/reports/FBgn0066101.html "FBgn0039363, FBgn0039364, FBgn0039365, FBgn0051095" protein_coding_gene "0004872=receptor activity, 0005509=calcium ion binding, 0005041=low-density lipoprotein receptor activity" "0042953=lipoprotein transport, 0006898=receptor-mediated endocytosis, 0008203=cholesterol metabolic process" 0016020=membrane "CG31095, LDL-receptor-related protein, lipophorin receptor 1, CG4874, CG4870, CT15569, lpr1, yolkless-like, CG4861, LpR1, CG31094" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR001881=EGF-like calcium-binding domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR000033=LDLR class B repeat, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site" CG31094 16-Dec-15 2015_12 ENSDARG00000006257(vldlr) WBGene00020481(T13C2.6) "ENSXETG00000011709(VLDLR),ENSXETG00000008073(LRP8),ENSXETG00000009352(LDLR)" "ENSMUSG00000024924(Vldlr),ENSMUSG00000028613,ENSMUSG00000032193(Ldlr)" "ENSG00000147852(VLDLR),ENSG00000130164(LDLR),ENSG00000157193(LRP8)" "viable,female fertile,fertile" FBgn0003038 pat patchytergum http://flybase.net/reports/FBgn0003038.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced,body color defective" "wing,ocellus,abdominal tergite 5,anterior" FBgn0038361 CG9589 http://flybase.net/reports/FBgn0038361.html FBgn0063343 protein_coding_gene 0004852=uroporphyrinogen-III synthase activity 0033014=tetrapyrrole biosynthetic process BcDNA:AT11468 "IPR003754=Tetrapyrrole biosynthesis, uroporphyrinogen III synthase" CG9589 16-Dec-15 2015_12 ENSDARG00000027491(uros) YOR278W(HEM4) ENSXETG00000025196(UROS) ENSMUSG00000030979(Uros) ENSG00000188690(UROS) FBgn0017563 Oef1 oe1 binding factor 1 http://flybase.net/reports/FBgn0017563.html gene 0003677=DNA binding 0005634=nucleus OEF1 16-Dec-15 2015_12 FBgn0032780 CG13085 http://flybase.net/reports/FBgn0032780.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO3 CG13085 16-Dec-15 2015_12 FBgn0263198 Acn Acinus http://flybase.net/reports/FBgn0263198.html "FBgn0086441, FBgn0002020, FBgn0032745, FBgn0262596" protein_coding_gene "0005515=protein binding, 0000166=nucleotide binding" "0008380=RNA splicing, 0000398=mRNA splicing, via spliceosome, 0000335=negative regulation of transposition, DNA-mediated, 0006622=protein targeting to lysosome, 0010506=regulation of autophagy, 0006915=apoptotic process" "0071013=catalytic step 2 spliceosome, 0005737=cytoplasm, 0005634=nucleus, 0071011=precatalytic spliceosome" "Ba, CG10473, acinus, dacn, Hook-like, CG10437, Drosophlia homolog of acinus, hook-like, lethal (2) 37Ba, dAcn, hkl, Acinus, l(2)37Ba" IPR012677=Nucleotide-binding alpha-beta plait domain CG10473 16-Dec-15 2015_12 "ENSDARG00000054290(acin1a),ENSDARG00000026842" ENSXETG00000025376(Q6NVM1_XENTR) ENSMUSG00000022185(Acin1) ENSG00000100813(ACIN1) DRSC02062 I 1.507061166 1.586493224 0.645977127 0.811754394 -0.649156411 0.121123388 FBgn0002141 l(2)K326 lethal (2) K326 http://flybase.net/reports/FBgn0002141.html gene 16-Dec-15 2015_12 lethal FBgn0013760 Cbp46A Calmodulin-binding protein 46A http://flybase.net/reports/FBgn0013760.html gene 0005516=calmodulin binding 16-Dec-15 2015_12 adult stage head

FBgn0044342 springer\pol pol http://flybase.net/reports/FBgn0044342.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration ORF2 "IPR001584=Integrase, catalytic core, IPR000477=Reverse transcriptase domain, IPR021109=Aspartic peptidase domain, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0028997 nmdyn-D7 nmdyn-D7 http://flybase.net/reports/FBgn0028997.html FBgn0037729 protein_coding_gene "0005524=ATP binding, 0004550=nucleoside diphosphate kinase activity" "0006241=CTP biosynthetic process, 0006228=UTP biosynthetic process, 0006183=GTP biosynthetic process, 0006165=nucleoside diphosphate phosphorylation, 0009142=nucleoside triphosphate biosynthetic process" 0005739=mitochondrion CG8362 "IPR001564=Nucleoside diphosphate kinase, IPR006602=Uncharacterised domain DM10, IPR011410=Nucleoside diphosphate kinase, NDK7" CG8362 16-Dec-15 2015_12 ENSDARG00000056193(nme7) ENSXETG00000002417(nme7) ENSMUSG00000026575(Nme7) ENSG00000143156(NME7) viable FBgn0263491 ScrPRE Sex-combs-reduced Polycomb group response element http://flybase.net/reports/FBgn0263491.html regulatory_region "Scr Polycomb Response Element, scrPRE, Scr PRE" 16-Dec-15 2015_12 FBgn0017446 anon-15Da anon-15Da http://flybase.net/reports/FBgn0017446.html gene transcript a 16-Dec-15 2015_12 FBgn0040245 anon-57Bc anon-57Bc http://flybase.net/reports/FBgn0040245.html gene 16-Dec-15 2015_12 FBgn0019879 anon-69Ad anon-69Ad http://flybase.net/reports/FBgn0019879.html gene 16-Dec-15 2015_12 " embryonic stage -- adult stage , embryonic stage&&pupal stage " FBgn0264907 CG44098 http://flybase.net/reports/FBgn0264907.html "FBgn0051530, FBgn0037271, FBgn0037272, FBgn0037273" protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity "0055085=transmembrane transport, 0015695=organic cation transport" 0016021=integral component of membrane "CG14654, CG9767, CG31530, CG12588" "IPR011701=Major facilitator superfamily, IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG44098 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" FBgn0038221 CG3259 http://flybase.net/reports/FBgn0038221.html protein_coding_gene 0008017=microtubule binding 0042384=cilium assembly "0005929=cilium, 0030990=intraciliary transport particle" "IFT54, MIP-T3" IPR018799=TRAF3-interacting protein 1 CG3259 16-Dec-15 2015_12 ENSDARG00000010300(traf3ip1) WBGene00001127(dyf-11) ENSXETG00000004877(TRAF3IP1) ENSMUSG00000034292(Traf3ip1) ENSG00000204104(TRAF3IP1) viable FBgn0004959 phm phantom http://flybase.net/reports/FBgn0004959.html "FBgn0000613, FBgn0003080, FBgn0030948" protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0005506=iron ion binding, 0020037=heme binding, 0035302=ecdysteroid 25-hydroxylase activity" "0048477=oogenesis, 0017143=insecticide metabolic process, 0055114=oxidation-reduction process, 0001700=embryonic development via the syncytial blastoderm, 0006697=ecdysone biosynthetic process, 0007298=border follicle cell migration" "0005783=endoplasmic reticulum, 0016020=membrane, 0043231=intracellular membrane-bounded organelle" "Cyp306a1, Cyp306a1-Dm, cytochrome P450, CYP306A1, PHM, exocephalon, ptm, CG6578, exo, 306a1" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG6578 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,maternal effect,circadian rhythm defective,viable,visible,body color defective" "ovary,embryonic/first instar larval cuticle,embryonic head,embryonic/larval hindgut,presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,stage 14 embryo,dorsal closure embryo,presumptive embryonic/larval digestive system,midgut primordium,embryo,border follicle cell,somatic clone,embryonic/larval cuticle,chaeta,supernumerary,mesothoracic tergum" DRSC20237 IE 0.445341058 2.506769234 1.613821022 -0.659958986 -1.36520105 0.655688151 FBgn0029605 CG18082 http://flybase.net/reports/FBgn0029605.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266891 CR45351 http://flybase.net/reports/FBgn0266891.html non_protein_coding_gene CR45351 16-Dec-15 2015_12 FBgn0038366 CG4576 http://flybase.net/reports/FBgn0038366.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" IPR002656=Acyltransferase 3 CG4576 16-Dec-15 2015_12 viable FBgn0065501 l(2)SH1207 lethal (2) SH1207 http://flybase.net/reports/FBgn0065501.html gene l(2)SH2 1207 16-Dec-15 2015_12 "lethal,recessive" FBgn0020809 mei-1916 mei-1916 http://flybase.net/reports/FBgn0020809.html gene 16-Dec-15 2015_12 FBgn0086387 BG01686 http://flybase.net/reports/FBgn0086387.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0082928 snoRNA:Me28S-G3255a snoRNA:Me28S-G3255a http://flybase.net/reports/FBgn0082928.html snoRNA_gene "DmSnR48a, CR34526, Me28S-G3255a(DmSnR48), Me28S-Gm3255a" CR34526 16-Dec-15 2015_12 FBgn0015533 rack on-the-rack http://flybase.net/reports/FBgn0015533.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" "presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral" FBgn0263473 snoRNA:abba-a http://flybase.net/reports/FBgn0263473.html snoRNA_gene CR43588 16-Dec-15 2015_12 FBgn0004668 Bsg99D Blastoderm-specific transcript 99D http://flybase.net/reports/FBgn0004668.html gene 16-Dec-15 2015_12 FBgn0266691 CR45181 http://flybase.net/reports/FBgn0266691.html non_protein_coding_gene CR45181 16-Dec-15 2015_12 FBgn0267792 rgr regular http://flybase.net/reports/FBgn0267792.html "FBgn0022235, FBgn0033310, FBgn0033311" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "lethal (2) k02605, CG14751, CG8643, l(2)k02605" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR029795=SNAIL family, IPR007087=Zinc finger, C2H2, IPR006578=MADF domain" CG8643 16-Dec-15 2015_12 "YLR375W(STP3),YDL048C(STP4)" WBGene00003380(mnm-2) FBgn0029097 anon-89Ec anon-89Ec http://flybase.net/reports/FBgn0029097.html gene "III, domain III" 16-Dec-15 2015_12 FBgn0030320 CG2247 http://flybase.net/reports/FBgn0030320.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0042742=defense response to bacterium" "0005634=nucleus, 0019005=SCF ubiquitin ligase complex" FBXL5 IPR001810=F-box domain CG2247 16-Dec-15 2015_12 "viable,fertile" FBgn0065708 l(2)SH0609 lethal (2) SH0609 http://flybase.net/reports/FBgn0065708.html gene l(2)SH2 0609 16-Dec-15 2015_12 "lethal,recessive" FBgn0267306 CR45742 http://flybase.net/reports/FBgn0267306.html non_protein_coding_gene CR45742 16-Dec-15 2015_12 FBgn0267951 CR46231 http://flybase.net/reports/FBgn0267951.html non_protein_coding_gene lincRNA.497 CR46231 16-Dec-15 2015_12 FBgn0052085 CG32085 http://flybase.net/reports/FBgn0052085.html "FBgn0036189, FBgn0036190, FBgn0063665" protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "BcDNA:RH06780, CG14134, FBXL16, CG6060, CT33735" CG32085 16-Dec-15 2015_12 ENSDARG00000060915 YJR052W(RAD7) ENSXETG00000015532(FBXL16) ENSMUSG00000025738(Fbxl16) ENSG00000127585(FBXL16) viable FBgn0028377 gdl-ORF39 gdl-ORF39 http://flybase.net/reports/FBgn0028377.html "FBgn0053088, FBgn0053755" protein_coding_gene 0007283=spermatogenesis "CG7268, CG33088, CG33755, ORF39" CG33755 16-Dec-15 2015_12 FBgn0267707 CR46040 http://flybase.net/reports/FBgn0267707.html non_protein_coding_gene CR46040 16-Dec-15 2015_12 FBgn0001767 l(1)M36 lethal (1) M36 http://flybase.net/reports/FBgn0001767.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0031343 CG18131 http://flybase.net/reports/FBgn0031343.html FBgn0061462 protein_coding_gene BcDNA:AT12853 CG18131 16-Dec-15 2015_12 "viable,fertile" FBgn0002756 mit(1)6 mitotic 6 http://flybase.net/reports/FBgn0002756.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0039690 CG1969 http://flybase.net/reports/FBgn0039690.html protein_coding_gene "0008080=N-acetyltransferase activity, 0004343=glucosamine 6-phosphate N-acetyltransferase activity" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG1969 16-Dec-15 2015_12 ENSDARG00000039892(gnpnat1) YFL017C(GNA1) WBGene00001646(gna-1) ENSXETG00000025513(gnpnat1) ENSMUSG00000037722(Gnpnat1) ENSG00000100522(GNPNAT1) viable FBgn0053469 CG33469 http://flybase.net/reports/FBgn0053469.html protein_coding_gene CG33469 16-Dec-15 2015_12 FBgn0067772 fragile-locus-D fragile locus D http://flybase.net/reports/FBgn0067772.html gene 0007343=egg activation 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0053544 Vkor Vitamin-K epoxide reductase http://flybase.net/reports/FBgn0053544.html "FBgn0069332, FBgn0082835" protein_coding_gene 0047057=vitamin-K-epoxide reductase (warfarin-sensitive) activity 0006766=vitamin metabolic process "unnamed, CG33544, BP1071, VKORC1, HDC06808" IPR012932=Vitamin K epoxide reductase CG33544 16-Dec-15 2015_12 ENSDARG00000043644(vkorc1l1) "ENSXETG00000010059(vkorc1l1),ENSXETG00000007049(vkorc1)" "ENSMUSG00000030804(Prss53),ENSMUSG00000066735(Vkorc1l1)" "ENSG00000167397(VKORC1),ENSG00000196715(VKORC1L1)" viable FBgn0262170 CG42878 http://flybase.net/reports/FBgn0262170.html protein_coding_gene chr2R_15474834_15475129.0 "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG42878 16-Dec-15 2015_12 FBgn0039110 RanBP3 Ran binding protein 3 http://flybase.net/reports/FBgn0039110.html protein_coding_gene "0051168=nuclear export, 0006611=protein export from nucleus, 0030178=negative regulation of Wnt signaling pathway" "RanBP3, GC10225, CG10225" "IPR000156=Ran binding domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG10225 16-Dec-15 2015_12 "ENSDARG00000069056(zgc:66385),ENSDARG00000008727(ranbp3)" YIL063C(YRB2) WBGene00004306(ran-5) ENSXETG00000025475(ranbp3) "ENSMUSG00000002372(Ranbp3),ENSMUSG00000048424" "ENSG00000031823(RANBP3),ENSG00000164188(RANBP3L)" "viable,fertile" FBgn0067903 IM18 Immune induced molecule 18 http://flybase.net/reports/FBgn0067903.html "FBgn0034881, FBgn0045894, FBgn0045895, FBgn0045896, FBgn0053706, FBgn0063722, FBpp0072018" protein_coding_gene "0009617=response to bacterium, 0098542=defense response to other organism, 0006952=defense response" 0005576=extracellular region "CG33706, DIM 18, anon-WO0153538.58, anon-WO0153538.57, BcDNA:AT19986, anon-WO0153538.56" CG33706 16-Dec-15 2015_12 "immune response defective,short lived,conditional" FBgn0036405 CG6833 http://flybase.net/reports/FBgn0036405.html protein_coding_gene 0003676=nucleic acid binding "IPR013520=Exonuclease, RNase T/DNA polymerase III, IPR012337=Ribonuclease H-like domain" CG6833 16-Dec-15 2015_12 ENSDARG00000021179(LOC100332469) YOL080C(REX4) WBGene00012465(Y17G7B.12) ENSXETG00000007588(AEN) "ENSMUSG00000030609(Aen),ENSMUSG00000048039(Isg20l2)" ENSG00000148300(REXO4) "viable,fertile" FBgn0062927 CR32735 http://flybase.net/reports/FBgn0062927.html FBgn0052735 non_protein_coding_gene BcDNA:RH57246 16-Dec-15 2015_12 FBgn0037710 CG9393 http://flybase.net/reports/FBgn0037710.html protein_coding_gene "0015031=protein transport, 0006839=mitochondrial transport, 0006626=protein targeting to mitochondrion" 0005741=mitochondrial outer membrane "IPR004046=Glutathione S-transferase, C-terminal, IPR031317=Tom37, C-terminal domain, IPR010987=Glutathione S-transferase, C-terminal-like, IPR017410=Mitochondrial outer membrane transport complex protein, metaxin, IPR019564=Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain" CG9393 16-Dec-15 2015_12 "ENSDARG00000036109(mtx1b),ENSDARG00000004605(mtx1a),ENSDARG00000030390(mtx3)" WBGene00009559(mtx-1) ENSXETG00000000510(MTX3) "ENSMUSG00000064068(Mtx1),ENSMUSG00000021704" ENSG00000173171(MTX1) "viable,fertile" FBgn0266840 CR45302 http://flybase.net/reports/FBgn0266840.html non_protein_coding_gene CR45302 16-Dec-15 2015_12 FBgn0065475 l(2)SH1311 lethal (2) SH1311 http://flybase.net/reports/FBgn0065475.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005707 l(1)TK110 lethal (1) TK110 http://flybase.net/reports/FBgn0005707.html gene l110 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0264527 ff20 http://flybase.net/reports/FBgn0264527.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" FBgn0039385 CG5913 http://flybase.net/reports/FBgn0039385.html protein_coding_gene IPR018797=Uncharacterised protein family FAM98 CG5913 16-Dec-15 2015_12 "ENSDARG00000060068(fam98b),ENSDARG00000070464" WBGene00044326(tag-322) "ENSXETG00000019357(FAM98A),ENSXETG00000018061()" "ENSMUSG00000002017(Fam98a),ENSMUSG00000027349(Fam98b)" "ENSG00000171262(FAM98B),ENSG00000119812(FAM98A)" "lethal,partially lethal - majority die,visible" trichogen cell FBgn0265752 CR44559 http://flybase.net/reports/FBgn0265752.html non_protein_coding_gene lincRNA.545 CR44559 16-Dec-15 2015_12 FBgn0262028 CR42839 http://flybase.net/reports/FBgn0262028.html non_protein_coding_gene CR42839 16-Dec-15 2015_12 FBgn0085779 CR40963 http://flybase.net/reports/FBgn0085779.html FBan0040963 rRNA_gene 16-Dec-15 2015_12 FBgn0029851 CG14445 http://flybase.net/reports/FBgn0029851.html protein_coding_gene CG14445 16-Dec-15 2015_12 viable FBgn0032176 CG13127 http://flybase.net/reports/FBgn0032176.html protein_coding_gene CG13127 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0029977 hdm hold'em http://flybase.net/reports/FBgn0029977.html protein_coding_gene "0003697=single-stranded DNA binding, 0005515=protein binding" 0000712=resolution of meiotic recombination intermediates 0043234=protein complex CG15329 "IPR012340=Nucleic acid-binding, OB-fold" CG15329 16-Dec-15 2015_12 ENSG00000162039(C16orf73) "meiotic cell cycle defective,viable" presumptive oocyte FBgn0052726 CG32726 http://flybase.net/reports/FBgn0052726.html FBgn0062923 protein_coding_gene BcDNA:RH59280 CG32726 16-Dec-15 2015_12 viable FBgn0040864 CG15755 http://flybase.net/reports/FBgn0040864.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265989 trp::trpl http://flybase.net/reports/FBgn0265989.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0065484 l(2)SH1269 lethal (2) SH1269 http://flybase.net/reports/FBgn0065484.html gene l(2)SH2 1269 16-Dec-15 2015_12 "lethal,recessive" FBgn0264694 mgr merry-go-round http://flybase.net/reports/FBgn0264694.html "FBgn0002738, FBgn0037893, FBgn0064920" protein_coding_gene 0048487=beta-tubulin binding "0007017=microtubule-based process, 0051297=centrosome organization, 0006457=protein folding, 0090307=mitotic spindle assembly, 0090306=spindle assembly involved in meiosis" "0005737=cytoplasm, 0016272=prefoldin complex" "CG6719, PAC10, BcDNA:LD34406" "IPR009053=Prefoldin, IPR004127=Prefoldin alpha-like, IPR016655=Prefoldin subunit 3" CG6719 16-Dec-15 2015_12 ENSDARG00000030241(vbp1) YGR078C(PAC10) WBGene00006889(pfd-3) ENSXETG00000001529(vbp1) ENSMUSG00000031197(Vbp1) ENSG00000155959(VBP1) FBgn0069430 JJF004 JJF004 http://flybase.net/reports/FBgn0069430.html gene 16-Dec-15 2015_12 stress response defective FBgn0259827 ifm(2)RS11 indirect flight muscle (2) RS11 http://flybase.net/reports/FBgn0259827.html gene 0007527=adult somatic muscle development 16-Dec-15 2015_12 viable indirect flight muscle FBgn0038106 CG7488 http://flybase.net/reports/FBgn0038106.html protein_coding_gene 0005525=GTP binding 0005875=microtubule associated complex "IPR030388=Era-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR015946=K homology domain-like, alpha/beta, IPR005225=Small GTP-binding protein domain, IPR006073=GTP binding domain" CG7488 16-Dec-15 2015_12 ENSDARG00000059887(eral1) WBGene00008456(E02H1.2) ENSXETG00000019633(ERAL1) ENSMUSG00000020832(Eral1) ENSG00000132591(ERAL1) "lethal,recessive" DRSC16250 K 0.537515372 0.938453102 0.166807554 0.104460585 -1.600181908 -0.813039694 FBgn0031451 CG9961 http://flybase.net/reports/FBgn0031451.html protein_coding_gene 0004618=phosphoglycerate kinase activity 0006096=glycolytic process 0005737=cytoplasm "IPR015911=Phosphoglycerate kinase, conserved site, IPR001576=Phosphoglycerate kinase, IPR015901=Phosphoglycerate kinase, C-terminal, IPR015824=Phosphoglycerate kinase, N-terminal" CG9961 16-Dec-15 2015_12 viable FBgn0038377 CG9632 http://flybase.net/reports/FBgn0038377.html "FBgn0045236, FBgn0061463" protein_coding_gene "BcDNA:AT06908, bs19g07.y1, NEST:bs19g07" CG9632 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050215 tRNA:CR30215 transfer RNA:CR30215 http://flybase.net/reports/FBgn0050215.html FBgn0060194 tRNA_gene 0033433=AUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR30215, AE002787.trna53-IleAAT, chr2R.trna36-IleAAT, tRNA:I:AAT:AE002787-h" CR30215 16-Dec-15 2015_12 FBgn0020509 Acp62F Accessory gland protein 62F http://flybase.net/reports/FBgn0020509.html protein_coding_gene "0030414=peptidase inhibitor activity, 0004867=serine-type endopeptidase inhibitor activity" "0045861=negative regulation of proteolysis, 0030162=regulation of proteolysis, 0008340=determination of adult lifespan, 0046692=sperm competition, 0032504=multicellular organism reproduction" 0005615=extracellular space "Accessory gland protein 62F, Accessory gland peptide 62F, CT2528, Acp62, Acp62f, CG1262" "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG1262 16-Dec-15 2015_12 "WBGene00044921(F53C11.9),WBGene00015683(C10G8.4)" "lethal,heat sensitive,viable" FBgn0082946 snoRNA:Me28S-A2634a snoRNA:Me28S-A2634a http://flybase.net/reports/FBgn0082946.html snoRNA_gene "Me28S-Am2634a, Me28S-A2634a, CR34636" CR34636 16-Dec-15 2015_12 FBgn0051591 tRNA:V4:90C tRNA:V4:90C http://flybase.net/reports/FBgn0051591.html "FBgn0003860, FBgn0004264, FBgn0012007, FBgn0012012, FBgn0012013, FBgn0060029" tRNA_gene "0033449=GUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Val-AAC], tRNA:val4:90Cb, transfer RNA:?:90Cc, transfer RNA:val4:90Cb, val-tRNA-4, valine tRNA, transfer RNA:val4:90Ca, tRNA:-?:90Cc, CR31591, chr3R.trna53-ValAAC, tRNA:val4:90Ca, tRNA:V4:90Cb, tRNA:V:AAC:AE002708-b, tRNA:V4, tRNA[Val][[4]], tRNA:V4:90Ca, tRNA-Val-4, Val-tRNA-4, AE002708.trna47-ValAAC" CR31591 16-Dec-15 2015_12 FBgn0040339 MED22 Mediator complex subunit 22 http://flybase.net/reports/FBgn0040339.html "FBgn0025972, FBgn0029541, FBgn0042153" protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0007067=mitotic nuclear division, 0007406=negative regulation of neuroblast proliferation, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex" "med22, Med22, CG3034, clone 1.82, Med24, EG:BACR7A4.6, 144358_at, dMED24, anon-EST:Liang-1.82, Srb6/Surf5, CG18830" IPR009332=Mediator of RNA polymerase II transcription subunit 22 CG3034 16-Dec-15 2015_12 ENSDARG00000014148(med22) WBGene00007022(mdt-22) ENSXETG00000005010(MED22) ENSMUSG00000015776(Med22) ENSG00000148297(MED22) DRSC18175 K -1.092840123 0.592541785 -0.52931813 1.149291411 0.615923301 2.25475101 FBgn0037073 Tsr1 Tsr1 ribosome assembly factor http://flybase.net/reports/FBgn0037073.html protein_coding_gene "0090277=positive regulation of peptide hormone secretion, 0022008=neurogenesis, 0042255=ribosome assembly, 0040018=positive regulation of multicellular organism growth" 0005730=nucleolus "CG7338, ribosome assembly factor Tsr1" "IPR012948=AARP2CN, IPR007034=Ribosome biogenesis protein BMS1/TSR1, C-terminal, IPR030387=Bms1/Tsr1-type G domain" CG7338 16-Dec-15 2015_12 ENSDARG00000007744(tsr1) YDL060W(TSR1) WBGene00006497(tag-151) ENSXETG00000023797(TSR1) ENSMUSG00000038335(Tsr1) ENSG00000167721(TSR1) "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0016906 l(3)X12 lethal (3) X12 http://flybase.net/reports/FBgn0016906.html gene X12 16-Dec-15 2015_12 FBgn0012037 Ance Angiotensin converting enzyme http://flybase.net/reports/FBgn0012037.html "FBgn0014013, FBgn0025190" protein_coding_gene "0008237=metallopeptidase activity, 0008241=peptidyl-dipeptidase activity, 0008270=zinc ion binding" "0007552=metamorphosis, 0009609=response to symbiotic bacterium, 0007289=spermatid nucleus differentiation, 0006508=proteolysis, 0007291=sperm individualization" "0005615=extracellular space, 0016020=membrane, 0005576=extracellular region" "race, unnamed, BG:DS08220.3, ANCE, anon-fast-evolving-3D10, anon-EST:fe3D10, angiotensin-converting enzyme, AnCE, CG8827, Angiotensin Converting Enzyme, Race, br31, Angiotensin I-converting enzyme, l(2)34Eb, ance, ACE, l(2)br31, Related to angiotensin converting enzyme, RACE, l34Eb" "IPR001548=Peptidase M2, peptidyl-dipeptidase A" CG8827 16-Dec-15 2015_12 ENSDARG00000016918(ace2) WBGene00000039(acn-1) ENSMUSG00000015405(Ace2) ENSG00000130234(ACE2) " embryonic stage | stage >9 , embryonic stage | late , embryonic stage | 4-12 hr , embryonic stage | stage 5-13 , embryonic stage -- adult stage " " posterior embryonic/larval midgut

, anterior embryonic/larval midgut

, pericardial cell

, amnioserosa

, embryonic/larval dorsal vessel

" "wild-type,lethal,recessive,partially lethal - majority live,male sterile,viable" "testis,spermatid,spermatid & nucleusAdh-nBR55),primary spermatocyte cyst,major mitochondrial derivativeAdh-nBR55),minor mitochondrial derivativeAdh-nBR55)" FBgn0003148 pre presto http://flybase.net/reports/FBgn0003148.html gene "0007349=cellularization, 0007279=pole cell formation" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0015770 MstProx MstProx http://flybase.net/reports/FBgn0015770.html protein_coding_gene 0004888=transmembrane signaling receptor activity "0006952=defense response, 0007165=signal transduction" "0016021=integral component of membrane, 0005886=plasma membrane" "DmMstProx, Toll-3, Tl-3, dToll3, toll, mstprox, CG1149, dTLR3" "IPR000372=Leucine-rich repeat N-terminal domain, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain" CG1149 16-Dec-15 2015_12 "viable,lethal" FBgn0085806 CR41585 http://flybase.net/reports/FBgn0085806.html FBan0041585 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0030949 Cyp308a1 Cyp308a1 http://flybase.net/reports/FBgn0030949.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding, 0005506=iron ion binding" "0017143=insecticide metabolic process, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG6585, 308a1" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG6585 16-Dec-15 2015_12 YHR007C(ERG11) viable FBgn0260308 GSd233 http://flybase.net/reports/FBgn0260308.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0001997 l(2)36Aa lethal (2) 36Aa http://flybase.net/reports/FBgn0001997.html gene "l(2)HT-5, l(2L)HT-5" 16-Dec-15 2015_12 "lethal,recessive" FBgn0065064 snoRNA:ë¬28S-291 http://flybase.net/reports/FBgn0065064.html FBgn0053754 snoRNA_gene 0005730=nucleolus "Dm-50, snoRNA:50, Psi28S-291, Psi 28S-291(SnoR50), CR33754, snoR50, Psi28s-291 snoRNA, chr3R:7049275..7049407, psi28s-291" CR33754 16-Dec-15 2015_12 FBgn0030918 CG15056 http://flybase.net/reports/FBgn0030918.html protein_coding_gene CG15056 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0259420 C436 http://flybase.net/reports/FBgn0259420.html gene 16-Dec-15 2015_12 visible "wing hair,wing" FBgn0005292 mei-2220 meiotic 2220 http://flybase.net/reports/FBgn0005292.html gene 2220 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0083936 Acp54A1 Accessory gland protein 54A1 http://flybase.net/reports/FBgn0083936.html protein_coding_gene 0032504=multicellular organism reproduction "Acp54A1, CG34098" CG34098 16-Dec-15 2015_12 FBgn0028246 l(3)S000107 lethal (3) S000107 http://flybase.net/reports/FBgn0028246.html "FBgn0060473, FBgn0060474, FBgn0061007, FBgn0061024, FBgn0061085, FBgn0061104" gene "0001/07, 1118/02, 0082/23, l(3)S111802, 0263/09, l(3)S025132, l(3)S026309, 1118/16, 0661/21, l(3)S012224, 0122/24, l(3)S111816, 0143/27, 0232/04, 0251/32, l(3)S008223, 0194/18" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0040515 CG17445 http://flybase.net/reports/FBgn0040515.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004817 fs(2)ltoAHK35 female sterile (2) ltoAHK35 http://flybase.net/reports/FBgn0004817.html gene 0007300=ovarian nurse cell to oocyte transport 16-Dec-15 2015_12 female sterile FBgn0259923 4-Sep Septin 4 http://flybase.net/reports/FBgn0259923.html "FBgn0026362, FBgn0030772" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0000281=mitotic cytokinesis 0005940=septin ring "sep4, Sep4, septin 4, CG9699, septin" "IPR030379=Septin-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR016491=Septin" CG9699 16-Dec-15 2015_12 "ENSDARG00000010385(sept4a),ENSDARG00000035683(sept4b),ENSDARG00000013843(sept5a),ENSDARG00000036031(sept5b)" "ENSMUSG00000072214(Sept5),ENSMUSG00000000486(Sept1)" "ENSG00000108387(SEPT4),ENSG00000184702(SEPT5),ENSG00000180096(SEPT1)" FBgn0030576 CG15890 http://flybase.net/reports/FBgn0030576.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG15890 16-Dec-15 2015_12 ENSDARG00000026149(slc46a1) YJL163C() "WBGene00021159(Y4C6B.5),WBGene00009582(F40F9.5),WBGene00012811(Y43F8A.5)" "viable,fertile" FBgn0265956 CR44743 http://flybase.net/reports/FBgn0265956.html non_protein_coding_gene lincRNA.44 CR44743 16-Dec-15 2015_12 FBgn0035903 CG6765 http://flybase.net/reports/FBgn0035903.html protein_coding_gene 0046872=metal ion binding "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG6765 16-Dec-15 2015_12 "viable,fertile" FBgn0029532 CG13361 http://flybase.net/reports/FBgn0029532.html protein_coding_gene CG13361 16-Dec-15 2015_12 viable FBgn0037188 CG7369 http://flybase.net/reports/FBgn0037188.html protein_coding_gene 0005088=Ras guanyl-nucleotide exchange factor activity "0043547=positive regulation of GTPase activity, 0008360=regulation of cell shape, 0046579=positive regulation of Ras protein signal transduction" "IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR023578=Ras guanine nucleotide exchange factor domain, IPR030710=Ras-GEF domain-containing family member 1B, IPR019804=Ras guanine-nucleotide exchange factor, conserved site, IPR001895=Ras guanine-nucleotide exchange factors catalytic domain" CG7369 16-Dec-15 2015_12 "ENSDARG00000044251(rasgef1bb),ENSDARG00000033614(rasgef1ba)" WBGene00019902(R05G6.10) "ENSXETG00000012564(rasgef1b),ENSXETG00000000607(rasgef1a)" "ENSMUSG00000029333(Rasgef1b),ENSMUSG00000020374(Rasgef1c)" "ENSG00000138670(RASGEF1B),ENSG00000146090(RASGEF1C),ENSG00000198915(RASGEF1A)" FBgn0023028 l(2)CA5 lethal (2) CA5 http://flybase.net/reports/FBgn0023028.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265168 CR44237 http://flybase.net/reports/FBgn0265168.html non_protein_coding_gene CR44237 16-Dec-15 2015_12 FBgn0065288 l(2)SH2018 lethal (2) SH2018 http://flybase.net/reports/FBgn0065288.html gene l(2)SH2 2018 16-Dec-15 2015_12 "lethal,recessive" FBgn0263649 CR43640 http://flybase.net/reports/FBgn0263649.html non_protein_coding_gene CR43640 16-Dec-15 2015_12 FBgn0061013 l(3)S026020b lethal (3) S026020b http://flybase.net/reports/FBgn0061013.html gene 0260/20 16-Dec-15 2015_12 FBgn0060791 l(3)S058712b lethal (3) S058712b http://flybase.net/reports/FBgn0060791.html gene 0587/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0016643 ER2-7B ER2-7B http://flybase.net/reports/FBgn0016643.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026760 Tehao Tehao http://flybase.net/reports/FBgn0026760.html protein_coding_gene "0005121=Toll binding, 0019901=protein kinase binding, 0015026=coreceptor activity, 0004888=transmembrane signaling receptor activity" "0045087=innate immune response, 0008063=Toll signaling pathway, 0002807=positive regulation of antimicrobial peptide biosynthetic process, 0007165=signal transduction, 0002121=inter-male aggressive behavior, 0006967=positive regulation of antifungal peptide biosynthetic process" "0005886=plasma membrane, 0016021=integral component of membrane" "CT22017, toll receptor, dToll5, Toll-5, tehao, Tho, CG7121, toll, dTLR5, Tl-5, Toll 5" "IPR026906=Leucine rich repeat 5, IPR001611=Leucine-rich repeat, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR000372=Leucine-rich repeat N-terminal domain, IPR003591=Leucine-rich repeat, typical subtype" CG7121 16-Dec-15 2015_12 "ENSDARG00000019742,ENSDARG00000022048(tlr4bb)" larval stage&&adult stage "behavior defective,recessive,viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,tormogen cell" FBgn0015335 anon-100Ab anon-100Ab http://flybase.net/reports/FBgn0015335.html gene T2 16-Dec-15 2015_12 FBgn0031758 Ucp4B Uncoupling protein 4B http://flybase.net/reports/FBgn0031758.html protein_coding_gene "0022857=transmembrane transporter activity, 0017077=oxidative phosphorylation uncoupler activity" "0006839=mitochondrial transport, 0015992=proton transport" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane" "dmUCP4b, Ucp4b, Ucp4B, uncoupling protein 4b, Ucp 4b, CG18340, UCP4B, DmUCP4B" "IPR018108=Mitochondrial substrate/solute carrier, IPR002030=Mitochondrial brown fat uncoupling protein, IPR023395=Mitochondrial carrier domain" CG18340 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0019665 p71 p71 http://flybase.net/reports/FBgn0019665.html gene 16-Dec-15 2015_12 FBgn0004095 l(2)60Dc lethal (2) 60Dc http://flybase.net/reports/FBgn0004095.html FBgn0016891 gene l(2)B485 16-Dec-15 2015_12 "lethal,recessive" FBgn0034308 CG10915 http://flybase.net/reports/FBgn0034308.html protein_coding_gene "IPR019131=Cortactin-binding protein-2, N-terminal" CG10915 16-Dec-15 2015_12 "ENSDARG00000056091(cttnbp2nl),ENSDARG00000053179" WBGene00016792(C49H3.6) ENSMUSG00000062127(Cttnbp2nl) ENSG00000143079(CTTNBP2NL) viable DRSC06469 K 1.470382858 -0.814945888 0.493387698 -1.187506264 1.158883908 1.749323853 FBgn0024591 l(2)k02705 lethal (2) k02705 http://flybase.net/reports/FBgn0024591.html gene 27/5 16-Dec-15 2015_12 "lethal,recessive" FBgn0013236 E(var)190 E(var)190 http://flybase.net/reports/FBgn0013236.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0044425 M80-39 M80-39 http://flybase.net/reports/FBgn0044425.html gene 0042067=establishment of ommatidial planar polarity "M80#A39, M80#39" 16-Dec-15 2015_12 "eye photoreceptor cell,somatic clone,eye equator,cell non-autonomous,ectopic" FBgn0058365 CG40365 http://flybase.net/reports/FBgn0058365.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267265 CR45701 http://flybase.net/reports/FBgn0267265.html non_protein_coding_gene CR45701 16-Dec-15 2015_12 FBgn0030753 rngo rings lost http://flybase.net/reports/FBgn0030753.html protein_coding_gene "0070628=proteasome binding, 0004190=aspartic-type endopeptidase activity, 0043130=ubiquitin binding" "0006508=proteolysis, 0007301=female germline ring canal formation" "0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" CG4420 "IPR015940=Ubiquitin-associated domain, IPR019103=Aspartic peptidase, DDI1-type, IPR021109=Aspartic peptidase domain, IPR000626=Ubiquitin domain, IPR009060=UBA-like, IPR001995=Peptidase A2A, retrovirus, catalytic, IPR029071=Ubiquitin-related domain" CG4420 16-Dec-15 2015_12 ENSDARG00000006477(ddi2) YER143W(DDI1) ENSXETG00000013448(Q497D6_XENTR) "ENSMUSG00000078515,ENSMUSG00000047619(Ddi1)" "ENSG00000197312(DDI2),ENSG00000170967(DDI1)" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,partially lethal - majority die" "female germline ring canal | germline clone,oocyte nucleus,germline clone" FBgn0013654 ms(2)ry1 ms(2)ry1 http://flybase.net/reports/FBgn0013654.html gene unnamed 16-Dec-15 2015_12 "female fertile,poor,male sterile" FBgn0260435 CR42530 http://flybase.net/reports/FBgn0260435.html pseudogene_attribute CR42530 16-Dec-15 2015_12 FBgn0263910 l(3)C79 http://flybase.net/reports/FBgn0263910.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0034135 Syn2 Syntrophin-like 2 http://flybase.net/reports/FBgn0034135.html protein_coding_gene "0008307=structural constituent of muscle, 0008092=cytoskeletal protein binding" "0042052=rhabdomere development, 0008582=regulation of synaptic growth at neuromuscular junction, 0001654=eye development, 0040011=locomotion" 0016013=syntrophin complex "Syntrophin 2, CG4905, Syntrophin-2, DmSYN-2" "IPR015482=Syntrophin, IPR001478=PDZ domain" CG4905 16-Dec-15 2015_12 "ENSDARG00000061832,ENSDARG00000059425(LOC569320)" WBGene00017866(stn-2) ENSXETG00000005667(SNTG1) "ENSMUSG00000025909(Sntg1),ENSMUSG00000020672(Sntg2)" "ENSG00000147481(SNTG1),ENSG00000172554(SNTG2)" "viable,locomotor behavior defective,increased cell death" "eye,ommatidium,ocellar bristle,rhabdomereGMR.PS,mesothoracic tergum" FBgn0031726 Cyp6a16 Cyp6a16 http://flybase.net/reports/FBgn0031726.html protein_coding_gene "0005506=iron ion binding, 0004497=monooxygenase activity, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "CG7249, Cyp6a16, Cyp6a16p, Cyp6a16Psi, CR7249, 6a16" "IPR017972=Cytochrome P450, conserved site, IPR002402=Cytochrome P450, E-class, group II, IPR001128=Cytochrome P450" CG7249 16-Dec-15 2015_12 FBgn0037035 CG10589 http://flybase.net/reports/FBgn0037035.html FBgn0044742 protein_coding_gene anon-WO0140519.139 CG10589 16-Dec-15 2015_12 viable FBgn0060499 l(3)S106810 lethal (3) S106810 http://flybase.net/reports/FBgn0060499.html gene 1068/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0037140 CG7442 http://flybase.net/reports/FBgn0037140.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG7442 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0037662 CG11997 http://flybase.net/reports/FBgn0037662.html protein_coding_gene CG11997 16-Dec-15 2015_12 FBgn0067068 N9 N9 http://flybase.net/reports/FBgn0067068.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal,partially lethal - majority die" "chaeta,pigment cell" FBgn0083005 snoRNA:ë¬28S-1175a snoRNA:ë¬28S-1175a http://flybase.net/reports/FBgn0083005.html snoRNA_gene "CR34558, Psi 28S-1175a, psi28s-1175a" CR34558 16-Dec-15 2015_12 FBgn0038714 Cpr92A Cuticular protein 92A http://flybase.net/reports/FBgn0038714.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr92A, CG6240" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG6240 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266950 CR45401 http://flybase.net/reports/FBgn0266950.html non_protein_coding_gene CR45401 16-Dec-15 2015_12 FBgn0033491 CG18011 http://flybase.net/reports/FBgn0033491.html FBgn0033492 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" CG17847 "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR017900=4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG18011 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC06706 I 1.602422265 0.591233627 1.073054019 -0.335849208 0.800112607 0.055312256 FBgn0065387 l(2)SH1635 lethal (2) SH1635 http://flybase.net/reports/FBgn0065387.html gene l(2)SH2 1635 16-Dec-15 2015_12 "lethal,recessive" FBgn0060571 l(3)S095814b lethal (3) S095814b http://flybase.net/reports/FBgn0060571.html gene 0958/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0053241 Ste:CG33241 Ste:CG33241 http://flybase.net/reports/FBgn0053241.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG33241, CG32605" "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet" CG33241 16-Dec-15 2015_12 FBgn0086254 CG6084 http://flybase.net/reports/FBgn0086254.html "FBgn0036182, FBgn0017641" protein_coding_gene 0004032=alditol:NADP+ 1-oxidoreductase activity 0055114=oxidation-reduction process "0005654=nucleoplasm, 0005829=cytosol" "Aldehyde reductase, 34F4T, ESTS:34F4T, Aldo/keto reductase" "IPR020471=Aldo/keto reductase subgroup, IPR023210=NADP-dependent oxidoreductase domain, IPR001395=Aldo/keto reductase, IPR018170=Aldo/keto reductase, conserved site" CG6084 16-Dec-15 2015_12 "ENSDARG00000045598(si:dkey-180p18.9),ENSDARG00000006215(akr1b1)" YHR104W(GRE3) WBGene00012722(Y39G8B.1) ENSXETG00000011530(akr1b1) "ENSMUSG00000052131(Akr1b7),ENSMUSG00000061758(Akr1b10),ENSMUSG00000029762(Akr1b8),ENSMUSG00000001642(Akr1b3)" "ENSG00000085662(AKR1B1),ENSG00000198074(AKR1B10)" FBgn0066057 amz amazon http://flybase.net/reports/FBgn0066057.html gene 0016319=mushroom body development 16-Dec-15 2015_12 "increased cell size,somatic clone,neuroanatomy defective" "embryonic/larval mushroom body,somatic clone" FBgn0267135 CR45575 http://flybase.net/reports/FBgn0267135.html non_protein_coding_gene lincRNA.730 CR45575 16-Dec-15 2015_12 FBgn0260085 2L3696 http://flybase.net/reports/FBgn0260085.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0011944 tRNA:P:90Ca transfer RNA:pro:90Ca http://flybase.net/reports/FBgn0011944.html "FBgn0003819, FBgn0051567, FBgn0060110" tRNA_gene "0033423=CCA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "Pro, tRNA:P:TGG:AE002708-e, tRNA:pro:90Ca, AE002708.trna51-ProTGG, chr3R.trna57-ProTGG, tRNA:Pro, CR31567" CR31567 16-Dec-15 2015_12 FBgn0030029 CG15343 http://flybase.net/reports/FBgn0030029.html protein_coding_gene "0010181=FMN binding, 0004733=pyridoxamine-phosphate oxidase activity" "0008615=pyridoxine biosynthetic process, 0055114=oxidation-reduction process" "IPR011576=Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, IPR012349=FMN-binding split barrel, IPR000659=Pyridoxamine 5'-phosphate oxidase" CG15343 16-Dec-15 2015_12 viable FBgn0027229 l(1)G0296 lethal (1) G0296 http://flybase.net/reports/FBgn0027229.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0035240 CG33791 http://flybase.net/reports/FBgn0035240.html "FBgn0035242, FBgn0052316, FBgn0053791, FBtr0072748, FBtr0072749, FBpp0072632, FBtr0072750, FBtr0072751, FBpp0072634, FBtr0072752, FBtr0072753" protein_coding_gene "0004591=oxoglutarate dehydrogenase (succinyl-transferring) activity, 0030976=thiamine pyrophosphate binding" 0006099=tricarboxylic acid cycle 0009353=mitochondrial oxoglutarate dehydrogenase complex "OGDH, CG32316, CG7934, CG13918, CG32316-ORFB" "IPR029061=Thiamin diphosphate-binding fold, IPR011603=2-oxoglutarate dehydrogenase E1 component, IPR001017=Dehydrogenase, E1 component, IPR005475=Transketolase-like, pyrimidine-binding domain" CG33791 16-Dec-15 2015_12 YIL125W(KGD1) DRSC08601 K -0.463705424 0.506691879 -0.417293371 0.088433317 1.593121282 0.200828548 FBgn0051685 CG31685 http://flybase.net/reports/FBgn0051685.html protein_coding_gene 16-Dec-15 2015_12 FBgn0051144 CR31144 http://flybase.net/reports/FBgn0051144.html non_protein_coding_gene CR31144 16-Dec-15 2015_12 FBgn0260595 2L2828 http://flybase.net/reports/FBgn0260595.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0015859 anon-14Ac anon-14Ac http://flybase.net/reports/FBgn0015859.html gene td39 16-Dec-15 2015_12 FBgn0023097 bon bonus http://flybase.net/reports/FBgn0023097.html "FBgn0038812, FBgn0038813, FBgn0060905, FBgn0062022" protein_coding_gene "0003682=chromatin binding, 0003713=transcription coactivator activity, 0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0006325=chromatin organization, 0048666=neuron development, 0007422=peripheral nervous system development, 0048813=dendrite morphogenesis, 0007411=axon guidance" "0000790=nuclear chromatin, 0005634=nucleus" "CG15687, 0241/08, Bon, 0434/20, 150268_at, 150269_at, anon-WO0118547.418, Bonus, CG5206, l(3)S043420, 0487/06, 0249/12" "IPR001965=Zinc finger, PHD-type, IPR001841=Zinc finger, RING-type, IPR019787=Zinc finger, PHD-finger, IPR001487=Bromodomain, IPR003649=B-box, C-terminal, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR000315=B-box-type zinc finger, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG5206 16-Dec-15 2015_12 ENSDARG00000016181(trim33) ENSXETG00000021457(trim33) "ENSMUSG00000029833(Trim24),ENSMUSG00000033014(Trim33),ENSMUSG00000031026(Trim66)" "ENSG00000122779(TRIM24),ENSG00000197323(TRIM33)" "visible,suppressor of variegation,dominant,body color defective,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,male,viable,female,reduced,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female limited,partially lethal - majority die,male limited,cell lethalcell lethal,somatic clone,increased cell death,enhancer of variegation" "eye,interommatidial bristle,ommatidium,wing,pupal abdomen & cuticle,abdominal tergite & macrochaeta,abdominal sternite bristle,wing margin bristle,neuron,head,embryonic/larval salivary gland,female,photoreceptor cell,somatic clone,adult head & cuticle | somatic clone,embryonic/larval tracheal system" DRSC16914 E -0.140195436 -0.740743091 -1.553476033 0.469098939 0.605946637 0.097094107 FBgn0266432 CG45062 http://flybase.net/reports/FBgn0266432.html protein_coding_gene "0000166=nucleotide binding, 0046872=metal ion binding" 0016021=integral component of membrane "alphalike, CG3701" "IPR008250=P-type ATPase, A domain, IPR006068=Cation-transporting P-type ATPase, C-terminal, IPR023214=HAD-like domain, IPR023299=P-type ATPase, cytoplasmic domain N, IPR001757=P-type ATPase, IPR023298=P-type ATPase, transmembrane domain" CG45062 16-Dec-15 2015_12 FBgn0038452 CG14905 http://flybase.net/reports/FBgn0038452.html protein_coding_gene 0036158=outer dynein arm assembly 0036157=outer dynein arm IPR029652=ODA1/DCC2 family CG14905 16-Dec-15 2015_12 ENSDARG00000015010(zgc:101737) ENSXETG00000010621(CCDC114) ENSMUSG00000043036(Ccdc63) ENSG00000173093(CCDC63) viable FBgn0266587 CR45112 http://flybase.net/reports/FBgn0266587.html non_protein_coding_gene CR45112 16-Dec-15 2015_12 FBgn0261401 Ir75c Ionotropic receptor 75c http://flybase.net/reports/FBgn0261401.html "FBgn0036758, FBgn0260865, FBan0014586, FBgn0261365" protein_coding_gene "0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" 0050907=detection of chemical stimulus involved in sensory perception "0016020=membrane, 0016021=integral component of membrane" "IR75c, DmelIR75c, CG14586-A, Ir75c, ionotropic receptor 75c, CG14586, CG42642, IR75abc" "IPR030406=Ionotropic receptor 75-related, IPR001320=Ionotropic glutamate receptor" CG42642 16-Dec-15 2015_12 FBgn0267043 CG45487 http://flybase.net/reports/FBgn0267043.html protein_coding_gene CG45487 16-Dec-15 2015_12 FBgn0037122 CG14570 http://flybase.net/reports/FBgn0037122.html protein_coding_gene CG14570 16-Dec-15 2015_12 viable FBgn0037408 NPFR Neuropeptide F receptor http://flybase.net/reports/FBgn0037408.html "FBgn0044358, FBgn0044359" protein_coding_gene "0008188=neuropeptide receptor activity, 0042263=neuropeptide F receptor activity, 0004983=neuropeptide Y receptor activity, 0004995=tachykinin receptor activity" "0007217=tachykinin receptor signaling pathway, 0007218=neuropeptide signaling pathway, 0030536=larval feeding behavior, 0007194=negative regulation of adenylate cyclase activity, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "neuropeptide F receptor, NPFR1, dNPFR1, neuropeptide F receptor-1, Neuropeptide F Receptor 1, anon-WO0131005.3, NPFR-1, npfr1, RE18294p, NPF-R, NPF-receptor, DmNPFR1, NPFR, Neuropeptide F receptor, CG1147, anon-WO0131005.5, NPFr, dNPF receptor" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000611=Neuropeptide Y receptor family" CG1147 16-Dec-15 2015_12 "ENSDARG00000005780(npy8br),ENSDARG00000043341(npy4r),ENSDARG00000037411(npy1r)" WBGene00016110(npr-11) ENSMUSG00000044014(Npy5r) "viable,fertile,memory defective,feeding behavior defective,chemical resistant,behavior defective,male" FBgn0066307 Bari2\ORF ORF http://flybase.net/reports/FBgn0066307.html transposable_element_gene 16-Dec-15 2015_12 FBgn0262648 l(2)47A3 lethal (2) 47A3 http://flybase.net/reports/FBgn0262648.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062644 EP646 EP646 http://flybase.net/reports/FBgn0062644.html gene EP(2)0646 16-Dec-15 2015_12 FBgn0019896 anon-2Ba anon-2Ba http://flybase.net/reports/FBgn0019896.html gene unnamed 16-Dec-15 2015_12 FBgn0034774 CG13526 http://flybase.net/reports/FBgn0034774.html FBgn0047347 protein_coding_gene 0005509=calcium ion binding BcDNA:AT13807 "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG13526 16-Dec-15 2015_12 viable FBgn0041124 l(2)45Am lethal (2) 45Am http://flybase.net/reports/FBgn0041124.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037885 CG17721 http://flybase.net/reports/FBgn0037885.html FBgn0063094 protein_coding_gene 0008270=zinc ion binding BcDNA:LP09251 "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG17721 16-Dec-15 2015_12 viable FBgn0069406 JJF237 JJF237 http://flybase.net/reports/FBgn0069406.html gene 16-Dec-15 2015_12 stress response defective FBgn0065548 l(2)SH1044 lethal (2) SH1044 http://flybase.net/reports/FBgn0065548.html gene l(2)SH2 1044 16-Dec-15 2015_12 "lethal,recessive" FBgn0011143 l(1)Q219 lethal (1) Q219 http://flybase.net/reports/FBgn0011143.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0042154 CG18831 http://flybase.net/reports/FBgn0042154.html protein_coding_gene 16-Dec-15 2015_12 FBgn0026177 skn skinhead http://flybase.net/reports/FBgn0026177.html gene "0008283=cell proliferation, 0007476=imaginal disc-derived wing morphogenesis, 0016055=Wnt signaling pathway" 16-Dec-15 2015_12 FBgn0000216 Brd Bearded http://flybase.net/reports/FBgn0000216.html protein_coding_gene 0005515=protein binding "0007423=sensory organ development, 0016360=sensory organ precursor cell fate determination, 0001708=cell fate specification, 0007219=Notch signaling pathway" "brd, DmelCG3096, Brd-C, CG3096, bearded" CG3096 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage | 4-8hr , prepupal stage | stage P4 " " morphogenetic furrow | vicinity of

, proneural cluster

, eye disc

, imaginal disc

, sensillum campaniformium &&of wing

, external sensory organ precursor cell

, morphogenetic furrow

, proneural cluster &&of imaginal disc

" "viable,visible,recessive,dominant,female fertile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,heat sensitive,lethal" "eye,microchaeta,macrochaeta,ectopic,sensillum trichodeum,sensillum campaniformium,sensillum basiconicum,anterior sternopleural bristle,anterior dorsocentral bristle,ocellar bristle,head bristle,heat sensitive,scutellar bristle,scutum & microchaeta-537.4,ommatidium,lens,interommatidial bristle,eye photoreceptor cell,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B" FBgn0053315 CR33315 http://flybase.net/reports/FBgn0053315.html pseudogene_attribute CR33315 16-Dec-15 2015_12 FBgn0262719 CG43163 http://flybase.net/reports/FBgn0262719.html "FBgn0035899, FBgn0035898" protein_coding_gene 0007346=regulation of mitotic cell cycle "0030496=midbody, 0005813=centrosome" "CG6902, CG6915" "IPR019734=Tetratricopeptide repeat, IPR028833=Tetratricopeptide repeat protein 28, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR024983=CHAT domain, IPR013105=Tetratricopeptide repeat 2" CG43163 16-Dec-15 2015_12 ENSMUSG00000033209(Ttc28) ENSG00000100154(TTC28) FBgn0041783 S(Sev-CycE)D28 S(Sev-CycE)D28 http://flybase.net/reports/FBgn0041783.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259118 mess messy mitochondria http://flybase.net/reports/FBgn0259118.html gene 16-Dec-15 2015_12 FBgn0062609 Mod(var)1322 Mod(var)1322 http://flybase.net/reports/FBgn0062609.html gene 0006342=chromatin silencing 1322 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0000514 dvr divers http://flybase.net/reports/FBgn0000514.html gene 16-Dec-15 2015_12 "semi-sterile,partially lethal - majority die,visible,wild-type" "wing,posterior scutellar bristle" FBgn0084038 CG41478 http://flybase.net/reports/FBgn0084038.html FBan0041478 protein_coding_gene 16-Dec-15 2015_12 FBgn0014979 l(2)30l lethal (2) 30l http://flybase.net/reports/FBgn0014979.html gene 16-Dec-15 2015_12 lethal FBgn0267955 CR46235 http://flybase.net/reports/FBgn0267955.html non_protein_coding_gene lincRNA.335 CR46235 16-Dec-15 2015_12 FBgn0000252 cal coal http://flybase.net/reports/FBgn0000252.html gene 16-Dec-15 2015_12 "visible,recessive,body color defective" FBgn0266883 CR45344 http://flybase.net/reports/FBgn0266883.html non_protein_coding_gene CR45344 16-Dec-15 2015_12 FBgn0010897 l(3)06664 lethal (3) 06664 http://flybase.net/reports/FBgn0010897.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0043464 18w::Tl 18w::Tl http://flybase.net/reports/FBgn0043464.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0002104 l(2)57De lethal (2) 57De http://flybase.net/reports/FBgn0002104.html gene 16-Dec-15 2015_12 lethal FBgn0030599 CG9030 http://flybase.net/reports/FBgn0030599.html protein_coding_gene CG9030 16-Dec-15 2015_12 viable FBgn0015436 l(1)5ACb lethal (1) 5ACb http://flybase.net/reports/FBgn0015436.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,visible" "wing,thorax" FBgn0011009 l(3)s1754 lethal (3) s1754 http://flybase.net/reports/FBgn0011009.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262621 CG43145 http://flybase.net/reports/FBgn0262621.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity lincRNA.26 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG43145 16-Dec-15 2015_12 FBgn0024152 ë±Tub84B::bcd ë±Tub84B::bcd http://flybase.net/reports/FBgn0024152.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0265792 CR44581 http://flybase.net/reports/FBgn0265792.html non_protein_coding_gene lincRNA.100 CR44581 16-Dec-15 2015_12 FBgn0086895 pea peanuts http://flybase.net/reports/FBgn0086895.html "FBgn0011228, FBgn0033898" protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0022008=neurogenesis, 0007286=spermatid development" "0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0005634=nucleus" "prp22, CG8241, cg8241, Prp22, Peanuts" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007502=Helicase-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011709=Domain of unknown function DUF1605, IPR022967=RNA-binding domain, S1, IPR012340=Nucleic acid-binding, OB-fold, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650=Helicase, C-terminal, IPR003029=S1 domain" CG8241 16-Dec-15 2015_12 ENSDARG00000054707(im:7153552) YER013W(PRP22) WBGene00003393(mog-5) ENSXETG00000013672(dhx8) ENSMUSG00000034931(Dhx8) ENSG00000067596(DHX8) DRSC07120 I -0.655126172 1.90293476 1.20572713 1.06831118 0.297519009 0.77536091 FBgn0037862 CG4706 http://flybase.net/reports/FBgn0037862.html protein_coding_gene "0051539=4 iron, 4 sulfur cluster binding, 0003994=aconitate hydratase activity" "0006099=tricarboxylic acid cycle, 0032504=multicellular organism reproduction" "0005739=mitochondrion, 0005615=extracellular space" "IPR006248=Aconitase, mitochondrial-like, IPR001030=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR015931=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR000573=Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR015928=Aconitase/3-isopropylmalate dehydratase, swivel, IPR015937=Aconitase/isopropylmalate dehydratase, IPR018136=Aconitase family, 4Fe-4S cluster binding site, IPR015932=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2" CG4706 16-Dec-15 2015_12 ENSDARG00000007294(aco2) YLR304C(ACO1) WBGene00000041(aco-2) ENSXETG00000006892(ACO2) ENSMUSG00000022477(Aco2) ENSG00000100412(ACO2) viable FBgn0050195 CG30195 http://flybase.net/reports/FBgn0050195.html FBgn0034754 protein_coding_gene CG13513 IPR006629=LPS-induced tumour necrosis factor alpha factor CG30195 16-Dec-15 2015_12 viable FBgn0040838 CG12599 http://flybase.net/reports/FBgn0040838.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053296 CG33296 http://flybase.net/reports/FBgn0053296.html protein_coding_gene 0005328=neurotransmitter:sodium symporter activity 0006836=neurotransmitter transport 0016021=integral component of membrane unnamed IPR000175=Sodium:neurotransmitter symporter CG33296 16-Dec-15 2015_12 FBgn0000727 frh fruh http://flybase.net/reports/FBgn0000727.html gene frh[RO] 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "stage 5 embryo,embryonic/first instar larval cuticle" FBgn0265083 CG44194 http://flybase.net/reports/FBgn0265083.html protein_coding_gene 0033108=mitochondrial respiratory chain complex assembly 0005758=mitochondrial intermembrane space IPR009069=Cysteine alpha-hairpin motif superfamily CG44194 16-Dec-15 2015_12 FBgn0015863 anon-240K anon-240K http://flybase.net/reports/FBgn0015863.html gene 16-Dec-15 2015_12 FBgn0259277 C480 http://flybase.net/reports/FBgn0259277.html gene 16-Dec-15 2015_12 visible "wing hair,wing margin" FBgn0263778 CR43695 http://flybase.net/reports/FBgn0263778.html non_protein_coding_gene "CG43695, mdcds_61307, CG15344" CR43695 16-Dec-15 2015_12 FBgn0033139 Tsp42Er Tetraspanin 42Er http://flybase.net/reports/FBgn0033139.html protein_coding_gene 0016021=integral component of membrane "tetraspanin 42E, CG12837, Dm.Tsp42Er" "IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin, IPR008952=Tetraspanin, EC2 domain" CG12837 16-Dec-15 2015_12 viable FBgn0005528 l(2)52ACe lethal (2) 52ACe http://flybase.net/reports/FBgn0005528.html gene unnamed 16-Dec-15 2015_12 FBgn0050401 CG30401 http://flybase.net/reports/FBgn0050401.html FBgn0034677 protein_coding_gene 0003677=DNA binding CG13496 "IPR009057=Homeodomain-like, IPR007889=DNA binding HTH domain, Psq-type" CG30401 16-Dec-15 2015_12 viable FBgn0086076 snoRNA:MeU2-A31 http://flybase.net/reports/FBgn0086076.html snoRNA_gene "CR34705, mgU2-31, MeU2-A31, MeU2-Am31" CR34705 16-Dec-15 2015_12 FBgn0003465 som sombre http://flybase.net/reports/FBgn0003465.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive,eye color defective,body color defective" "pigment cell,wing" FBgn0035134 CG1231 http://flybase.net/reports/FBgn0035134.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR000690=Zinc finger, C2H2-type matrin, IPR022755=Zinc finger, double-stranded RNA binding, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR003604=Zinc finger, U1-type" CG1231 16-Dec-15 2015_12 "ENSDARG00000060695(zgc:158750),ENSDARG00000061419" "ENSXETG00000002298(ZNF385C),ENSXETG00000014010(ZNF385D),ENSXETG00000015059(ZNF385B),ENSXETG00000021272(ZNF385A)" "ENSMUSG00000037492(Zmat4),ENSMUSG00000021481(Zfp346)" ENSG00000166432(ZMAT1) viable DRSC08267 I 1.629500545 2.611051055 0.849073902 -0.695067752 0.251734551 0.228278987 FBgn0002646 mapA midgut amylase pattern AMG http://flybase.net/reports/FBgn0002646.html gene map-AMG 16-Dec-15 2015_12 FBgn0085279 CG34250 http://flybase.net/reports/FBgn0085279.html protein_coding_gene CG34250 16-Dec-15 2015_12 FBgn0051019 CG31019 http://flybase.net/reports/FBgn0051019.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR000834=Peptidase M14, carboxypeptidase A" CG31019 16-Dec-15 2015_12 ENSDARG00000045900(agbl5) WBGene00017136(EEED8.6) ENSMUSG00000061298 ENSG00000186094(AGBL4) FBgn0035476 CG12766 http://flybase.net/reports/FBgn0035476.html protein_coding_gene 0004032=alditol:NADP+ 1-oxidoreductase activity 0055114=oxidation-reduction process "IPR001395=Aldo/keto reductase, IPR018170=Aldo/keto reductase, conserved site, IPR020471=Aldo/keto reductase subgroup, IPR023210=NADP-dependent oxidoreductase domain" CG12766 16-Dec-15 2015_12 "YOR120W(GCY1),YDR368W(YPR1)" DRSC08295 K -0.284076084 0.338433952 0.71554448 0.449239076 -1.601557257 -0.169450502 FBgn0083257 E(smoDN)986 Enhancer of smoDN 986 http://flybase.net/reports/FBgn0083257.html gene 16-Dec-15 2015_12 FBgn0084455 l(3)S000710 l(3)S000710 http://flybase.net/reports/FBgn0084455.html gene 16-Dec-15 2015_12 FBgn0035694 CG13299 http://flybase.net/reports/FBgn0035694.html protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion CG13299 16-Dec-15 2015_12 viable FBgn0002548 Lg Large http://flybase.net/reports/FBgn0002548.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "microchaeta,wing vein L4,wing vein L5,wing,postvertical bristle" FBgn0034797 nahoda nahoda http://flybase.net/reports/FBgn0034797.html protein_coding_gene 0019028=viral capsid "CT36793, CG12781" "IPR000082=SEA domain, IPR005018=DOMON domain, IPR013032=EGF-like, conserved site, IPR013111=EGF-like domain, extracellular, IPR000742=EGF-like domain, IPR004302=Chitin-binding, domain 3" CG12781 16-Dec-15 2015_12 WBGene00007479(C09F9.2) viable FBgn0034470 Obp56d Odorant-binding protein 56d http://flybase.net/reports/FBgn0034470.html "FBgn0043829, FBgn0063051" protein_coding_gene 0005549=odorant binding "0019236=response to pheromone, 0007606=sensory perception of chemical stimulus, 0042048=olfactory behavior" 0005576=extracellular region "BEST:GH09027, obp56d, DmelObp56d, OBP56d, 56d, CG11218, BcDNA:RE22207, CT31326" IPR006170=Pheromone/general odorant binding protein CG11218 16-Dec-15 2015_12 adult stage proboscis

viable FBgn0029964 CG1409 http://flybase.net/reports/FBgn0029964.html FBgn0063289 protein_coding_gene 0030150=protein import into mitochondrial matrix 0005744=mitochondrial inner membrane presequence translocase complex "BcDNA:AT29287, D.M.BLPp" IPR005341=Mitochondrial import inner membrane translocase subunit Tim16 CG1409 16-Dec-15 2015_12 YJL104W(PAM16) WBGene00009734(F45G2.8) ENSXETG00000017310(AY313218.1) viable FBgn0014244 l(2)32Ae lethal (2) 32Ae http://flybase.net/reports/FBgn0014244.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0019957 ND-42 NADH dehydrogenase (ubiquinone) 42 kDa subunit http://flybase.net/reports/FBgn0019957.html protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" "0005759=mitochondrial matrix, 0005739=mitochondrion, 0005811=lipid particle, 0005747=mitochondrial respiratory chain complex I" "CG6343, NdufA10, A10, ND42, NUDM, NADH:ubiquinone reductase 42 kD, NADH:ubiquinone oxidoreductase 42 kDa subunit, NADH-ubiquinone oxidoreductase subunit, NADH ubiquinone oxidoreductase 42 kDa, NADH-ubiquinone oxidoreductase 42 kDa subunit, NADH:ubiquinone reductase 42kD subunit precursor, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, NADH: UBIQUINONE REDUCTASE 42 KD SUBUNIT PRECURSOR" "IPR015828=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, IPR031314=Deoxynucleoside kinase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6343 16-Dec-15 2015_12 ENSDARG00000013333(ndufa10) WBGene00019401(nuo-4) ENSXETG00000004886(BC087982.1) ENSMUSG00000026260(Ndufa10) ENSG00000130414(NDUFA10) "neuroanatomy defective,progressive,viable,visible,body color defective" "rhabdomere,progressive,eye photoreceptor cell,retinal pigment cell,trichogen cell,mesothoracic tergum" FBgn0001184 hdp-b heldup b http://flybase.net/reports/FBgn0001184.html gene hdp 16-Dec-15 2015_12 visible wing FBgn0060496 l(3)S107707 lethal (3) S107707 http://flybase.net/reports/FBgn0060496.html gene 1077/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0002379 l(3)93Ba lethal (3) 93Ba http://flybase.net/reports/FBgn0002379.html gene "er7, l(3)er7" 16-Dec-15 2015_12 "lethal,recessive" FBgn0002046 l(2)37Dj lethal (2) 37Dj http://flybase.net/reports/FBgn0002046.html gene l(2)OE31 16-Dec-15 2015_12 lethal FBgn0058122 CG40122 http://flybase.net/reports/FBgn0058122.html FBan0040122 protein_coding_gene 16-Dec-15 2015_12 FBgn0030351 CG1840 http://flybase.net/reports/FBgn0030351.html FBgn0062464 protein_coding_gene "BcDNA:LD12750, AAF48112" IPR024491=Selenoprotein SelK/SelG CG1840 16-Dec-15 2015_12 FBgn0058172 CR40172 http://flybase.net/reports/FBgn0058172.html non_protein_coding_gene CG40172 CR40172 16-Dec-15 2015_12 FBgn0060464 l(3)S114602 lethal (3) S114602 http://flybase.net/reports/FBgn0060464.html gene 1146/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0035193 CG9192 http://flybase.net/reports/FBgn0035193.html protein_coding_gene CG9192 16-Dec-15 2015_12 viable FBgn0259394 EP-380 http://flybase.net/reports/FBgn0259394.html gene 16-Dec-15 2015_12 "visible,planar polarity defective" wing FBgn0013583 l(3)ry85 lethal (3) ry85 http://flybase.net/reports/FBgn0013583.html gene l(3)85 16-Dec-15 2015_12 "lethal,recessive" FBgn0000766 fs(1)A1010 female sterile (1) A1010 http://flybase.net/reports/FBgn0000766.html gene fs(1)1010ts 16-Dec-15 2015_12 "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect,blastoderm embryo" FBgn0025492 l(3)82Da lethal (3) 82Da http://flybase.net/reports/FBgn0025492.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060591 l(3)S093108a lethal (3) S093108a http://flybase.net/reports/FBgn0060591.html gene 0931/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0051077 CG31077 http://flybase.net/reports/FBgn0051077.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG31077 16-Dec-15 2015_12 WBGene00010351(cbd-1) "viable,fertile" FBgn0021753 3L-B 3L-B http://flybase.net/reports/FBgn0021753.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 16-Dec-15 2015_12 "visible,dominant,viable" wing FBgn0062648 EP443 EP443 http://flybase.net/reports/FBgn0062648.html gene EP(X)0443 16-Dec-15 2015_12 FBgn0261788 Ank2 Ankyrin 2 http://flybase.net/reports/FBgn0261788.html "FBgn0085445, FBgn0042181, FBgn0035810, FBgn0035809, FBgn0035808, FBgn0017645, FBgn0083993, FBgn0052375, FBgn0083957, FBgn0052377, FBgn0261687" protein_coding_gene "0005200=structural constituent of cytoskeleton, 0008092=cytoskeletal protein binding" "0007016=cytoskeletal anchoring at plasma membrane, 0007605=sensory perception of sound, 0048675=axon extension, 0000226=microtubule cytoskeleton organization, 0007165=signal transduction, 0070050=neuron cellular homeostasis, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0007528=neuromuscular junction development, 0007614=short-term memory, 1900074=negative regulation of neuromuscular synaptic transmission" "0043195=terminal bouton, 0042734=presynaptic membrane, 0005886=plasma membrane, 0036062=presynaptic periactive zone, 0031594=neuromuscular junction" "CG32377/CG34416, CG7493, Ank2, ankyrin2-XL, CG42734, SP2523, dank2, CG32373, ank2-L, CG32377, sp2523, CG7462, DAnk2, CG34121, ESTS:149B10S, ankyrin2, CG18768, CG34416, CG18025, Dank2, ank2, CG34158, CG18227, CG32375, Ankyrin2" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR000906=ZU5 domain, IPR011029=Death-like domain, IPR000488=Death domain" CG42734 16-Dec-15 2015_12 "ENSDARG00000043313(ank2),ENSDARG00000061736(LOC794638)" WBGene00006780(unc-44) ENSMUSG00000069601(Ank3) "ENSG00000151150(ANK3),ENSG00000145362(ANK2)" FBgn0003419 slb slim body http://flybase.net/reports/FBgn0003419.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" FBgn0012034 AcCoAS Acetyl Coenzyme A synthase http://flybase.net/reports/FBgn0012034.html FBgn0043802 protein_coding_gene "0016208=AMP binding, 0003987=acetate-CoA ligase activity" "0019427=acetyl-CoA biosynthetic process from acetate, 0006084=acetyl-CoA metabolic process, 0048149=behavioral response to ethanol" 0005737=cytoplasm "acetate-coenzyme A ligase, BEST:GH28401, Acetyl CoA synthetase, AcCoAs, acetyl-coenzyme A synthase, CG9390, acetyl CoA synthase, dACS, Acetyl CoA synthase, Acetyl-CoA synthase, Acetyl-CoA sythase, AcetylCoA synthase, acetyl CoA synthetase, ACS, acetyl-CoA synthetase, acetyl coenzyme A synthase, Ac CoA synthase" "IPR025110=AMP-binding enzyme C-terminal domain, IPR011904=Acetate-CoA ligase, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG9390 16-Dec-15 2015_12 ENSDARG00000037781(acss2) "YLR153C(ACS2),YAL054C(ACS1)" WBGene00007969(acs-19) "ENSXETG00000007473(ACSS2),ENSXETG00000004291()" ENSMUSG00000027605(Acss2) ENSG00000131069(ACSS2) "viable,fertile,hypoactive,conditional,chemical sensitive,smell perception defective" FBgn0084274 2.1.72 2.1.72 http://flybase.net/reports/FBgn0084274.html gene 16-Dec-15 2015_12 "sterile,eye color defective" pigment cell FBgn0040645 CG14581 http://flybase.net/reports/FBgn0040645.html protein_coding_gene 16-Dec-15 2015_12 "partially lethal - majority die,visible" mesothoracic tergum FBgn0000815 fs(1)K524 female sterile (1) K524 http://flybase.net/reports/FBgn0000815.html gene 16-Dec-15 2015_12 "female sterile,recessive,visible,heat sensitive" "eye,macrochaeta,ovary" FBgn0266178 pre-mod(mdg4)-B http://flybase.net/reports/FBgn0266178.html protein_coding_gene CG44884 "IPR007588=Zinc finger, FLYWCH-type" CG44884 16-Dec-15 2015_12 FBgn0265650 CR44457 http://flybase.net/reports/FBgn0265650.html non_protein_coding_gene lincRNA.312 CR44457 16-Dec-15 2015_12 FBgn0036918 CG7770 http://flybase.net/reports/FBgn0036918.html FBgn0063213 protein_coding_gene "0051082=unfolded protein binding, 0051087=chaperone binding" "0006458='de novo' protein folding, 0006457=protein folding, 0022008=neurogenesis" 0016272=prefoldin complex BcDNA:GH28557 "IPR009053=Prefoldin, IPR002777=Prefoldin beta-like" CG7770 16-Dec-15 2015_12 ENSDARG00000037108(pfdn6) YLR200W(YKE2) WBGene00009004(pfd-6) ENSXETG00000020401(hke2) ENSMUSG00000024309(H2-Ke2) "ENSG00000206211,ENSG00000204220(PFDN6),ENSG00000206283" "lethal,neuroanatomy defective" ganglion mother cell FBgn0050490 CG30490 http://flybase.net/reports/FBgn0050490.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039854 CG1635 http://flybase.net/reports/FBgn0039854.html protein_coding_gene IPR029069=HotDog domain CG1635 16-Dec-15 2015_12 "ENSDARG00000058352(acot9),ENSDARG00000058390(zgc:123262)" "WBGene00019015(F57F4.1),WBGene00020311(T07D3.9)" ENSXETG00000006223(ACOT9) "ENSMUSG00000025287(Acot9),ENSMUSG00000047565(Acot10)" ENSG00000123130(ACOT9) viable DRSC25487 K 0.404437391 0.340482547 0.736627187 -0.111049377 1.875449349 0.102175915 FBgn0004090 l(2)60Ca lethal (2) 60Ca http://flybase.net/reports/FBgn0004090.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003127 port port http://flybase.net/reports/FBgn0003127.html gene 16-Dec-15 2015_12 "visible,eye color defective" pigment cell FBgn0037782 Npc2d Niemann-Pick type C-2d http://flybase.net/reports/FBgn0037782.html protein_coding_gene 0032934=sterol binding 0015918=sterol transport "CG12813, npc2d" "IPR014756=Immunoglobulin E-set, IPR003172=MD-2-related lipid-recognition domain" CG12813 16-Dec-15 2015_12 viable FBgn0034948 Gadd34 http://flybase.net/reports/FBgn0034948.html protein_coding_gene 0008157=protein phosphatase 1 binding 0005783=endoplasmic reticulum "dGADD34, Dm-GADD34, gadd34, dPPP1R15, GADD34, CG3825" "IPR019523=Protein phosphatase 1, regulatory subunit 15A/B, C-terminal" CG3825 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage,some die during embryonic stage,developmental rate defective,viable,fertile" mesothoracic tergum DRSC04422 IE -0.678635744 -2.816865093 -1.955411417 -2.743336041 0.03544586 0.130304194 FBgn0005042 E(var)28AB Enhancer of variegation 28AB http://flybase.net/reports/FBgn0005042.html gene unnamed 16-Dec-15 2015_12 FBgn0033652 ths thisbe http://flybase.net/reports/FBgn0033652.html protein_coding_gene 0005104=fibroblast growth factor receptor binding "0021782=glial cell development, 0007507=heart development, 0007498=mesoderm development, 0010001=glial cell differentiation, 0007442=hindgut morphogenesis, 0007523=larval visceral muscle development, 0051451=myoblast migration, 0008543=fibroblast growth factor receptor signaling pathway, 0007526=larval somatic muscle development" "Ths, Thisbe, CG12443, DFGF8-1, FGF8-like1, Neu4, fgf8-like, DmThs" "IPR008996=Cytokine, IL-1-like" CG12443 16-Dec-15 2015_12 embryonic stage | stage 5 ventral neurogenic region

"partially lethal - majority die,recessive,cell migration defective,some die during embryonic stage,viable,fertile" "glial cell,mesoderm,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,segment border muscle,embryonic/larval midgut longitudinal visceral muscle,longitudinal visceral muscle primordium,ventral oblique muscle,longitudinal visceral muscle primordium | embryonic stage 12,longitudinal visceral muscle primordium | embryonic stage 13,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 17,embryonic pericardial cell,supernumerary,eye photoreceptor cell" FBgn0265795 CR44584 http://flybase.net/reports/FBgn0265795.html non_protein_coding_gene CR44584 16-Dec-15 2015_12 FBgn0262767 Su(E1)-A gene ; SO:0000704 http://flybase.net/reports/FBgn0262767.html gene 16-Dec-15 2015_12 lethal FBgn0065863 l(2)SH0271 lethal (2) SH0271 http://flybase.net/reports/FBgn0065863.html gene l(2)SH2 0271 16-Dec-15 2015_12 "lethal,recessive" FBgn0265596 CR44423 http://flybase.net/reports/FBgn0265596.html non_protein_coding_gene CR44423 16-Dec-15 2015_12 FBgn0038705 CG11626 http://flybase.net/reports/FBgn0038705.html protein_coding_gene 0004185=serine-type carboxypeptidase activity 0006508=proteolysis "IPR029058=Alpha/Beta hydrolase fold, IPR008758=Peptidase S28" CG11626 16-Dec-15 2015_12 viable FBgn0262365 CG43063 http://flybase.net/reports/FBgn0262365.html protein_coding_gene MIP20204 CG43063 16-Dec-15 2015_12 FBgn0011427 l(3)j10B6 lethal (3) j10B6 http://flybase.net/reports/FBgn0011427.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011977 tRNA:S4:12Ee transfer RNA:ser4:12Ee http://flybase.net/reports/FBgn0011977.html "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052608, FBgn0060061" tRNA_gene "0033408=UCG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "Ser-tRNA-4, transfer RNA:ser, 444[[T50]], Ser tRNA[Ser], unnamed, tRNA:S, tRNA:S4, AE002593.trna13-SerCGA, CR32608, tRNA:ser4:12Ee, transfer RNA:ser4, tRNA:ser, tRNA:S:CGA:AE002593-c, 444-T50, chrX.trna22-SerCGA, tRNA-Ser, tRNA[Ser], tRNA:ser4, tRNA[[Ser]]" CR32608 16-Dec-15 2015_12 FBgn0038102 CG14383 http://flybase.net/reports/FBgn0038102.html protein_coding_gene CG14383 16-Dec-15 2015_12 FBgn0024340 KHD-11 KH domain cDNA KHD-11 http://flybase.net/reports/FBgn0024340.html gene unnamed 16-Dec-15 2015_12 FBgn0027264 l(1)G0221 lethal (1) G0221 http://flybase.net/reports/FBgn0027264.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0065525 l(2)SH1120 lethal (2) SH1120 http://flybase.net/reports/FBgn0065525.html gene l(2)SH2 1120 16-Dec-15 2015_12 "lethal,recessive" FBgn0051331 tRNA:CR31331 transfer RNA:CR31331 http://flybase.net/reports/FBgn0051331.html FBgn0060231 tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002708.trna54-PheGAA, tRNA:F:GAA:AE002708-c, CR31331, chr3R.trna60-PheGAA" CR31331 16-Dec-15 2015_12 FBgn0034151 CG15617 http://flybase.net/reports/FBgn0034151.html protein_coding_gene CT35755 "IPR001478=PDZ domain, IPR017351=LIM and senescent cell antigen-like-containing domain protein 1" CG15617 16-Dec-15 2015_12 viable FBgn0036250 Ir68b Ionotropic receptor 68b http://flybase.net/reports/FBgn0036250.html protein_coding_gene "0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" 0009593=detection of chemical stimulus "0016020=membrane, 0016021=integral component of membrane" "CT38092, DmelIR68b, ionotropic receptor 68b, CG17152, IR68b" IPR001320=Ionotropic glutamate receptor CG17152 16-Dec-15 2015_12 FBgn0017434 anon-28Ce anon-28Ce http://flybase.net/reports/FBgn0017434.html gene unnamed 16-Dec-15 2015_12 FBgn0000518 dw-b dwarf b http://flybase.net/reports/FBgn0000518.html gene 16-Dec-15 2015_12 visible "adult abdomen,adult thorax" FBgn0037685 Or85f Odorant receptor 85f http://flybase.net/reports/FBgn0037685.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "CG16755, DOR32, DmOr85f, 85f, 85D.1" "IPR004117=Olfactory receptor, Drosophila" CG16755 16-Dec-15 2015_12 viable FBgn0020323 anon-82Fa anon-82Fa http://flybase.net/reports/FBgn0020323.html gene 506 16-Dec-15 2015_12 FBgn0267966 CR46246 http://flybase.net/reports/FBgn0267966.html non_protein_coding_gene CR46246 16-Dec-15 2015_12 FBgn0011139 l(1)Q215 lethal (1) Q215 http://flybase.net/reports/FBgn0011139.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0266824 CR45286 http://flybase.net/reports/FBgn0266824.html non_protein_coding_gene CR45286 16-Dec-15 2015_12 FBgn0267339 p38c p38c MAP kinase http://flybase.net/reports/FBgn0267339.html "FBgn0046322, FBgn0053338, FBgn0020401" protein_coding_gene "0004707=MAP kinase activity, 0005524=ATP binding" "0048082=regulation of adult chitin-containing cuticle pigmentation, 1902882=regulation of response to oxidative stress, 0010883=regulation of lipid storage, 0006468=protein phosphorylation, 0009617=response to bacterium, 0007165=signal transduction" 0005737=cytoplasm "dMPK2B, p38c, Dp38c, dp38c, P38c, CG33338, Mpk2B" "IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG33338 16-Dec-15 2015_12 FBgn0021738 Crg-1 Circadianly Regulated Gene http://flybase.net/reports/FBgn0021738.html FBgn0052788 protein_coding_gene "0003690=double-stranded DNA binding, 0043565=sequence-specific DNA binding, 0008301=DNA binding, bending, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0048806=genitalia development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0009888=tissue development, 0048813=dendrite morphogenesis, 0007389=pattern specification process" "0005634=nucleus, 0005667=transcription factor complex" "CG32788, crg1, Crg1" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain" CG32788 16-Dec-15 2015_12 viable FBgn0028133 l(3)S051007a lethal (3) S051007a http://flybase.net/reports/FBgn0028133.html gene "0510/07, l(3)S051007" 16-Dec-15 2015_12 "lethal,recessive" FBgn0021860 l(2)k14308 lethal (2) k14308 http://flybase.net/reports/FBgn0021860.html gene 16-Dec-15 2015_12 FBgn0001888 l(2)21Db lethal (2) 21Db http://flybase.net/reports/FBgn0001888.html gene "l(2)neh2, l(2)neh-2" 16-Dec-15 2015_12 lethal FBgn0082305 Ndg::LpR2 Ndg::LpR2 http://flybase.net/reports/FBgn0082305.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0015037 Cyp4p1 Cytochrome P450-4p1 http://flybase.net/reports/FBgn0015037.html "FBgn0033396, FBgn0044596" protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "cytochrome P450, P-450, CG10842, P450, anon-WO0140519.35, 4p1" "IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450" CG10842 16-Dec-15 2015_12 YDR402C(DIT2) viable FBgn0037814 CG6325 http://flybase.net/reports/FBgn0037814.html protein_coding_gene CG6325 16-Dec-15 2015_12 ENSMUSG00000037103(Dcaf15) ENSG00000132017(DCAF15) "viable,fertile,visible" mesothoracic tergum FBgn0002806 ms(1)20Aa male sterile (1) 20Aa http://flybase.net/reports/FBgn0002806.html gene "ms(1)B, ms(1)20A" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0266273 T:GPI-lynx1 GPI targeting signal of lynx1 protoxin http://flybase.net/reports/FBgn0266273.html engineered_foreign_region 16-Dec-15 2015_12 FBgn0024886 l(2)00455b lethal (2) 00455b http://flybase.net/reports/FBgn0024886.html gene "l(2)00455, 0455" 16-Dec-15 2015_12 "lethal,recessive" FBgn0067643 sve sverdrup http://flybase.net/reports/FBgn0067643.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 lethal "dorsal appendage,germline clone,egg" FBgn0264503 CG43902 http://flybase.net/reports/FBgn0264503.html "FBgn0030182, FBgn0040940" protein_coding_gene "CG12644, CG15311" CG43902 16-Dec-15 2015_12 DRSC17999 IEK 1.196193199 -2.610716765 -0.605066916 -3.483496782 -0.909908606 -2.343080512 FBgn0264865 CR44056 http://flybase.net/reports/FBgn0264865.html non_protein_coding_gene CR44056 16-Dec-15 2015_12 FBgn0030999 Mur18B Mucin related 18B http://flybase.net/reports/FBgn0030999.html FBgn0044762 protein_coding_gene "0005201=extracellular matrix structural constituent, 0008061=chitin binding" 0006030=chitin metabolic process "0005576=extracellular region, 0031012=extracellular matrix" "Mur18B, CG7874, anon-WO0140519.120" IPR002557=Chitin binding domain CG7874 16-Dec-15 2015_12 viable FBgn0040713 CG15392 http://flybase.net/reports/FBgn0040713.html protein_coding_gene 16-Dec-15 2015_12 FBgn0261994 CG42812 http://flybase.net/reports/FBgn0261994.html "FBan0018669, FBgn0040599" protein_coding_gene CG18669 IPR006631=Protein of unknown function DM4/12 CG42812 16-Dec-15 2015_12 FBgn0037141 DNApol-ëá DNApol-ëá http://flybase.net/reports/FBgn0037141.html protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0003684=damaged DNA binding" "0009314=response to radiation, 0009650=UV protection, 0000724=double-strand break repair via homologous recombination, 0019985=translesion synthesis" 0005634=nucleus "DNApoleta, DNA polymerase eta, DNA pol-eta, DNApol-eta, Dmpol eta, AAF51794, pol eta, drad30A, polymerase eta, POLH, pol h, dPoleta, CG7143, DNA pol eta" "IPR017961=DNA polymerase, Y-family, little finger domain, IPR001126=UmuC domain, IPR017061=DNA polymerase eta/kappa" CG7143 16-Dec-15 2015_12 ENSDARG00000070231(zgc:136881) YDR419W(RAD30) WBGene00018721(polh-1) ENSXETG00000005087(Q6DJA4_XENTR) ENSMUSG00000023953(Polh) ENSG00000170734(POLH) "viable,fertile,radiation sensitive,maternal effect,chemical sensitive,DNA repair defective,visible,partially lethal - majority die,some die during pupal stage" "mitotic spindle | maternal effectBSC284),mitotic spindle | maternal effect,trichogen cell,mesothoracic tergum" FBgn0065918 l(2)SH0161 lethal (2) SH0161 http://flybase.net/reports/FBgn0065918.html gene l(2)SH2 0161 16-Dec-15 2015_12 "lethal,recessive" FBgn0264946 CR44115 http://flybase.net/reports/FBgn0264946.html non_protein_coding_gene CR44115 16-Dec-15 2015_12 FBgn0003173 pwc pink wing c http://flybase.net/reports/FBgn0003173.html gene pw-c 16-Dec-15 2015_12 "eye color defective,recessive,visible,viable,poor" "pigment cell,wing" FBgn0069116 mus214 mutagen-sensitive 214 http://flybase.net/reports/FBgn0069116.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0038354 CG5404 http://flybase.net/reports/FBgn0038354.html protein_coding_gene 0015381=high-affinity sulfate transmembrane transporter activity "0008272=sulfate transport, 0055085=transmembrane transport" 0016021=integral component of membrane "IPR011547=SLC26A/SulP transporter domain, IPR001902=SLC26A/SulP transporter" CG5404 16-Dec-15 2015_12 "YLR092W(SUL2),YBR294W(SUL1)" viable DRSC15793 E 1.025096929 0.693032021 1.900732867 1.34301919 -0.561009081 -0.150266804 FBgn0038877 CG3308 http://flybase.net/reports/FBgn0038877.html protein_coding_gene "0016888=endodeoxyribonuclease activity, producing 5'-phosphomonoesters, 0004536=deoxyribonuclease activity" IPR001130=TatD family CG3308 16-Dec-15 2015_12 "ENSDARG00000054076(tatdn3),ENSDARG00000044072" WBGene00000795(crn-2) long lived "germline cell,male" FBgn0022995 ned no endurance http://flybase.net/reports/FBgn0022995.html gene "0007269=neurotransmitter secretion, 0048489=synaptic vesicle transport" 16-Dec-15 2015_12 FBgn0020873 anon-P241 anon-P241 http://flybase.net/reports/FBgn0020873.html gene 2-P241 16-Dec-15 2015_12 "fertile,chemical sensitive,dominant" FBgn0030406 CG1463 http://flybase.net/reports/FBgn0030406.html protein_coding_gene 0048812=neuron projection morphogenesis "IPR007529=Zinc finger, HIT-type" CG1463 16-Dec-15 2015_12 YHR040W(BCD1) ENSXETG00000003093(ZNHIT6) ENSMUSG00000074182(Znhit6) "viable,visible" trichogen cell DRSC19603 I 3.095424287 0.443510766 1.178367911 0.48168804 -0.364500751 0.275324612 FBgn0065242 l(2)SH2149 lethal (2) SH2149 http://flybase.net/reports/FBgn0065242.html gene l(2)SH2 2149 16-Dec-15 2015_12 "lethal,recessive" FBgn0038681 Cyp12a4 Cyp12a4 http://flybase.net/reports/FBgn0038681.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0017085=response to insecticide" 0005739=mitochondrion "cytochrome P450, CYP12A4, cyp12a4, P450, CG6042, 12a4" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG6042 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" "viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001688 l(1)ESHS9 lethal (1) ESHS9 http://flybase.net/reports/FBgn0001688.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036772 CG5290 http://flybase.net/reports/FBgn0036772.html protein_coding_gene 0022008=neurogenesis "IPR013105=Tetratricopeptide repeat 2, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain" CG5290 16-Dec-15 2015_12 ENSDARG00000007918(ttc27) YNL313C() WBGene00020600(T20B12.1) ENSXETG00000017701(TTC27) ENSMUSG00000024078(Ttc27) ENSG00000018699(TTC27) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0001271 irreB irregular optic chiasma B http://flybase.net/reports/FBgn0001271.html gene 16-Dec-15 2015_12 FBgn0025942 anon-89Ba anon-89Ba http://flybase.net/reports/FBgn0025942.html gene 89B-ov2.5 16-Dec-15 2015_12 adult stage ovary

FBgn0266243 CR44938 http://flybase.net/reports/FBgn0266243.html non_protein_coding_gene lincRNA.736 CR44938 16-Dec-15 2015_12 FBgn0036038 defl deflated http://flybase.net/reports/FBgn0036038.html protein_coding_gene "0016180=snRNA processing, 0034472=snRNA 3'-end processing" "0005634=nucleus, 0032039=integrator complex, 0005737=cytoplasm" "CG18176, Integrator 7, Int7, IntS7" IPR016024=Armadillo-type fold CG18176 16-Dec-15 2015_12 ENSDARG00000019300(ints7) WBGene00008361(D1043.1) ENSXETG00000014409() ENSMUSG00000037461(Ints7) ENSG00000143493(INTS7) "male fertile,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,female fertile,reduced,visible,viable" "dorsal appendage,maternal effect,chorion | maternal effect,anterior crossvein,ectopic,wing,macrochaeta & mesothoracic tergumesg-p127,macrochaeta & mesothoracic tergumarm.PS,mesothoracic tergum,tergite,genitalia,wing vein L5,humeral bristle,adult abdomen" DRSC10300 IE 2.029347656 -2.629531054 0.971239028 -1.867773739 -0.182937955 0.089930885 FBgn0259429 EP-A7 http://flybase.net/reports/FBgn0259429.html gene 16-Dec-15 2015_12 visible wing FBgn0004689 posterior-cell-blister posterior cell blister http://flybase.net/reports/FBgn0004689.html gene pcb 16-Dec-15 2015_12 visible "wing,2nd posterior cell" FBgn0053444 5SrRNA:CR33444 5SrRNA:CR33444 http://flybase.net/reports/FBgn0053444.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33444 CR33444 16-Dec-15 2015_12 FBgn0085592 CG41276 http://flybase.net/reports/FBgn0085592.html FBan0041276 protein_coding_gene 16-Dec-15 2015_12 FBgn0051041 CG31041 http://flybase.net/reports/FBgn0051041.html protein_coding_gene IPR007931=Protein of unknown function DUF725 CG31041 16-Dec-15 2015_12 viable FBgn0085322 CG34293 http://flybase.net/reports/FBgn0085322.html protein_coding_gene IPR024512=Small subunit of serine palmitoyltransferase-like CG34293 16-Dec-15 2015_12 "ENSDARG00000041778(zgc:136867),ENSDARG00000071203(zgc:112487)" WBGene00044784(F13H10.8) "ENSXETG00000008728(C3orf57),ENSXETG00000024869(Q6DFT6_XENTR)" "ENSG00000196542(SPTSSB),ENSG00000165389(SPTSSA)" FBgn0000888 fs(1)M86 female sterile (1) M86 http://flybase.net/reports/FBgn0000888.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0037283 CG14658 http://flybase.net/reports/FBgn0037283.html protein_coding_gene CG14658 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0260476 CG30153 http://flybase.net/reports/FBgn0260476.html FBgn0050153 protein_coding_gene 16-Dec-15 2015_12 FBgn0033372 CG13742 http://flybase.net/reports/FBgn0033372.html FBgn0063157 protein_coding_gene BcDNA:LD16446 CG13742 16-Dec-15 2015_12 viable FBgn0263471 scaRNA:MeU2-48 small Cajal body-specific RNA : MeU2-48 http://flybase.net/reports/FBgn0263471.html snoRNA_gene 0030563=snRNA 2'-O-ribose methylation guide activity 0015030=Cajal body "mgU2-48, scaRNA:pUf68-a" CR43586 16-Dec-15 2015_12 FBgn0038986 CG5278 http://flybase.net/reports/FBgn0038986.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane IPR002076=ELO family CG5278 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0085263 CG34234 http://flybase.net/reports/FBgn0085263.html protein_coding_gene CG34234 16-Dec-15 2015_12 FBgn0032473 CG5204 http://flybase.net/reports/FBgn0032473.html FBgn0062169 protein_coding_gene anon-WO0118547.212 "IPR015880=Zinc finger, C2H2-like" CG5204 16-Dec-15 2015_12 viable FBgn0035928 CG13310 http://flybase.net/reports/FBgn0035928.html protein_coding_gene IPR000859=CUB domain CG13310 16-Dec-15 2015_12 viable FBgn0023505 Fas2::Nrg Fas2::Nrg http://flybase.net/reports/FBgn0023505.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0043968 U5E3 U5E3 http://flybase.net/reports/FBgn0043968.html gene 0009950=dorsal/ventral axis specification 16-Dec-15 2015_12 FBgn0085790 CR41507 http://flybase.net/reports/FBgn0085790.html FBan0041507 pseudogene_attribute CR41507 16-Dec-15 2015_12 FBgn0028219 l(3)S007902 lethal (3) S007902 http://flybase.net/reports/FBgn0028219.html gene 0079/02 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0000843 fs(1)M30 female sterile (1) M30 http://flybase.net/reports/FBgn0000843.html gene 16-Dec-15 2015_12 female sterile chorion FBgn0044008 Su(rst)B188 Su(rst)B188 http://flybase.net/reports/FBgn0044008.html gene 0001745=compound eye morphogenesis B188 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0085491 CG34462 http://flybase.net/reports/FBgn0085491.html FBgn0035874 protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG7072, DmelCpr66Ca, Cpr66Ca" IPR000618=Insect cuticle protein CG34462 16-Dec-15 2015_12 viable FBgn0085802 18SrRNA:CR41548 18S ribosomal RNA:CR41548 http://flybase.net/reports/FBgn0085802.html FBan0041548 rRNA_gene CR41548 CR41548 16-Dec-15 2015_12 FBgn0260999 AGAR-21 Autosomal general anesthetic resistant 21 http://flybase.net/reports/FBgn0260999.html gene autosomal general anesthetic resistant 21 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0039689 CIA30 "Complex I intermediate-associated protein, 30 kDa" http://flybase.net/reports/FBgn0039689.html protein_coding_gene 0051082=unfolded protein binding "0001666=response to hypoxia, 0007005=mitochondrion organization, 0006119=oxidative phosphorylation, 0055093=response to hyperoxia, 0006120=mitochondrial electron transport, NADH to ubiquinone, 0009408=response to heat, 0042594=response to starvation, 0032981=mitochondrial respiratory chain complex I assembly" 0005747=mitochondrial respiratory chain complex I "CI30, dCIA30, Complex I intermediate- associate protein 30, Complex I intermediate-associated protein 30, CG7598" "IPR008979=Galactose-binding domain-like, IPR013857=NADH:ubiquinone oxidoreductase intermediate-associated protein 30" CG7598 16-Dec-15 2015_12 ENSDARG00000025549(ndufaf1) WBGene00008225(C50B8.3) ENSXETG00000017902(ndufaf1) ENSMUSG00000027305(Ndufaf1) ENSG00000137806(NDUFAF1) viable FBgn0058138 CG40138 http://flybase.net/reports/FBgn0058138.html FBan0040138 protein_coding_gene 16-Dec-15 2015_12 FBgn0024648 l(2)k09502 lethal (2) k09502 http://flybase.net/reports/FBgn0024648.html gene 95/2 16-Dec-15 2015_12 "lethal,recessive" FBgn0043870 nompI no mechanoreceptor potential I http://flybase.net/reports/FBgn0043870.html gene 0007605=sensory perception of sound 16-Dec-15 2015_12 "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0028417 Mao Monoamine oxidase http://flybase.net/reports/FBgn0028417.html gene 0008131=primary amine oxidase activity 0005741=mitochondrial outer membrane MAO 16-Dec-15 2015_12 FBgn0051448 CG31448 http://flybase.net/reports/FBgn0051448.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035575 CG7509 http://flybase.net/reports/FBgn0035575.html protein_coding_gene "tartan/capricious-like, CT1509" "IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal, IPR001611=Leucine-rich repeat" CG7509 16-Dec-15 2015_12 "ENSDARG00000062303,ENSDARG00000070792(lrrc15)" "ENSXETG00000001152(SLITRK3),ENSXETG00000013348(SLITRK6)" "ENSG00000172061(LRRC15),ENSG00000178732(GP5)" FBgn0026308 agee antenno-glial expressed http://flybase.net/reports/FBgn0026308.html gene 0007625=grooming behavior D5 16-Dec-15 2015_12 "grooming behavior defective,recessive" FBgn0004884 bwk bullwinkle http://flybase.net/reports/FBgn0004884.html gene "0007304=chorion-containing eggshell formation, 0007297=ovarian follicle cell migration, 0007476=imaginal disc-derived wing morphogenesis, 0046843=dorsal appendage formation, 0046594=maintenance of pole plasm mRNA location, 0009952=anterior/posterior pattern specification" 16-Dec-15 2015_12 "female sterile germline-dependent,female sterile,visible,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect,lethal" "dorsal appendage,embryo,follicle cell,chorion,wing vein,ectopic,wing,chorion | anterior" FBgn0040591 CG13828 http://flybase.net/reports/FBgn0040591.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028668 Vha16-2 Vacuolar H+ ATPase 16kD subunit 2 http://flybase.net/reports/FBgn0028668.html "FBgn0036163, FBgn0052089" protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" "0015991=ATP hydrolysis coupled proton transport, 0006909=phagocytosis" "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "CG7547, Vacuolar H[+] ATPase subunit 16-2, vha16-2, Vha16-2, CG32089" "IPR002379=V-ATPase proteolipid subunit C-like domain, IPR000245=V-ATPase proteolipid subunit, IPR011555=V-ATPase proteolipid subunit C, eukaryotic" CG32089 16-Dec-15 2015_12 WBGene00006912(vha-3) "viable,fertile,visible" mesothoracic tergum FBgn0003445 smp small pallid http://flybase.net/reports/FBgn0003445.html gene 16-Dec-15 2015_12 "viable,visible,male fertile,female sterile,body color defective" "macrochaeta,eye" FBgn0250832 Dup99B Ductus ejaculatorius peptide 99B http://flybase.net/reports/FBgn0250832.html "FBgn0024381, FBgn0053495, FBgn0066985" protein_coding_gene "0005179=hormone activity, 0001664=G-protein coupled receptor binding" "0018991=oviposition, 0007186=G-protein coupled receptor signaling pathway, 0045434=negative regulation of female receptivity, post-mating, 0032504=multicellular organism reproduction, 0007621=negative regulation of female receptivity, 0046662=regulation of oviposition" "0005576=extracellular region, 0005615=extracellular space" "DUP99B, anon-SAGE:Wang-013, CG33495, DUP" IPR012608=Sex peptide CG33495 16-Dec-15 2015_12 FBgn0030189 CG2909 http://flybase.net/reports/FBgn0030189.html protein_coding_gene CG2909 16-Dec-15 2015_12 "viable,fertile" FBgn0266457 CR45082 http://flybase.net/reports/FBgn0266457.html non_protein_coding_gene CR45082 16-Dec-15 2015_12 FBgn0085694 CG41563 http://flybase.net/reports/FBgn0085694.html FBan0041563 protein_coding_gene 16-Dec-15 2015_12 FBgn0259584 B2028 http://flybase.net/reports/FBgn0259584.html gene 16-Dec-15 2015_12 visible leg FBgn0030648 CG6340 http://flybase.net/reports/FBgn0030648.html protein_coding_gene 0005654=nucleoplasm IPR028124=Small acidic protein-like domain CG6340 16-Dec-15 2015_12 ENSDARG00000042534(rsrc2) WBGene00022579(ZC262.2) ENSXETG00000007798(TTpA011p02.1) ENSMUSG00000029422(Rsrc2) ENSG00000111011(RSRC2) "viable,fertile" DRSC19987 K 0.001639136 -1.089947542 -0.017903421 -0.302849359 0.611020067 1.593446838 FBgn0267134 CR45574 http://flybase.net/reports/FBgn0267134.html non_protein_coding_gene lincRNA.730 CR45574 16-Dec-15 2015_12 FBgn0026090 CG14812 http://flybase.net/reports/FBgn0026090.html FBgn0062994 protein_coding_gene "0071230=cellular response to amino acid stimulus, 0019079=viral genome replication, 0032008=positive regulation of TOR signaling, 0043154=negative regulation of cysteine-type endopeptidase activity involved in apoptotic process" 0005737=cytoplasm "dHBXIP, EG:131F2.3, BcDNA:RE59545" IPR024135=Hepatitis B X-interacting protein CG14812 16-Dec-15 2015_12 ENSXETG00000025722(HBXIP) ENSG00000134248(HBXIP) viable FBgn0034842 Prosë_5R1 Proteasome ë_5 subunit-related 1 http://flybase.net/reports/FBgn0034842.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0005839=proteasome core complex, 0019774=proteasome core complex, beta-subunit complex" "Prosbeta5R1, Proteasome beta5R subunit, CG9868, Prosbeta5R, beta5R1" "IPR016050=Proteasome beta-type subunit, conserved site, IPR001353=Proteasome, subunit alpha/beta, IPR000243=Peptidase T1A, proteasome beta-subunit, IPR023333=Proteasome B-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal" CG9868 16-Dec-15 2015_12 ENSDARG00000038723(LOC100331926) YPR103W(PRE2) WBGene00003951(pbs-5) ENSXETG00000026351() "ENSMUSG00000022193(Psmb5),ENSMUSG00000024338(Psmb8)" "ENSG00000100804(PSMB5),ENSG00000206298,ENSG00000204264(PSMB8),ENSG00000206234" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0050054 CG30054 http://flybase.net/reports/FBgn0050054.html protein_coding_gene "0001664=G-protein coupled receptor binding, 0031683=G-protein beta/gamma-subunit complex binding, 0003924=GTPase activity, 0004871=signal transducer activity, 0005525=GTP binding" 0007186=G-protein coupled receptor signaling pathway 0005834=heterotrimeric G-protein complex "IPR000654=G-protein alpha subunit, group Q, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011025=G protein alpha subunit, helical insertion" CG30054 16-Dec-15 2015_12 viable FBgn0051491 tRNA:CR31491 transfer RNA:CR31491 http://flybase.net/reports/FBgn0051491.html FBgn0060212 tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033463=GGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002699.trna3-GlyTCC, chr3R.trna76-GlyTCC, CR31491, tRNA:G:TCC:AE002699-a" CR31491 16-Dec-15 2015_12 FBgn0014211 l(2)31Aa lethal (2) 31Aa http://flybase.net/reports/FBgn0014211.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265715 CR44522 http://flybase.net/reports/FBgn0265715.html non_protein_coding_gene "lincRNA.450, incRNA.450" CR44522 16-Dec-15 2015_12 FBgn0265011 Np Notopleural http://flybase.net/reports/FBgn0265011.html "FBgn0002963, FBgn0085379, FBgn0033360, FBgn0033361" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG34350, np, CG8181, notopleural, SP59, CG11824" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG34350 16-Dec-15 2015_12 ENSDARG00000045889 "WBGene00006625(try-7),WBGene00006624(try-6)" ENSXETG00000017966() ENSMUSG00000022857(Tmprss15) FBgn0005681 ire irregular eye http://flybase.net/reports/FBgn0005681.html gene 0048749=compound eye development 16-Dec-15 2015_12 "visible,recessive" "eye,ommatidium,photoreceptor cell R7,eye photoreceptor cell" FBgn0065349 l(2)SH1808 lethal (2) SH1808 http://flybase.net/reports/FBgn0065349.html gene l(2)SH2 1808 16-Dec-15 2015_12 "lethal,recessive" FBgn0020783 sept seven pentacosene http://flybase.net/reports/FBgn0020783.html gene 0042810=pheromone metabolic process 16-Dec-15 2015_12 FBgn0267659 CR45997 http://flybase.net/reports/FBgn0267659.html non_protein_coding_gene lincRNA.339 CR45997 16-Dec-15 2015_12 FBgn0022005 l(2)k09238 lethal (2) k09238 http://flybase.net/reports/FBgn0022005.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036274 CG4328 http://flybase.net/reports/FBgn0036274.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding, 0043565=sequence-specific DNA binding" "0006909=phagocytosis, 0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain, IPR001781=Zinc finger, LIM-type" CG4328 16-Dec-15 2015_12 "ENSDARG00000068365(lmx1b.1),ENSDARG00000019306,ENSDARG00000020354(si:ch211-260g14.3)" YDL106C(PHO2) ENSXETG00000000742(LMX1B) ENSMUSG00000038765(Lmx1b) "ENSG00000162761(LMX1A),ENSG00000136944(LMX1B)" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC23146 K -1.818202919 -0.03893374 FBgn0263518 mir-4975 mir-4975 stem loop http://flybase.net/reports/FBgn0263518.html miRNA_gene "CR43503, dme-mir-4975" CR43503 16-Dec-15 2015_12 FBgn0262400 mir-287 mir-287 stem loop http://flybase.net/reports/FBgn0262400.html "FBgn0067705, FBgn0262232" miRNA_gene "CR42939, CR33603, miR-287, mir-287, Mir-287" CR42939 16-Dec-15 2015_12 viable FBgn0039686 CG15506 http://flybase.net/reports/FBgn0039686.html protein_coding_gene CG15506 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0012032 1731\RTase 1731-repetitive-element reverse transcriptase http://flybase.net/reports/FBgn0012032.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration ORF2 "IPR013103=Reverse transcriptase, RNA-dependent DNA polymerase, IPR001584=Integrase, catalytic core, IPR025724=GAG-pre-integrase domain, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0037430 Osi20 Osiris 20 http://flybase.net/reports/FBgn0037430.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG15188" IPR012464=Protein of unknown function DUF1676 CG15188 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0046882 Lar::Ptp69D Lar::Ptp69D http://flybase.net/reports/FBgn0046882.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0259849 Su(Ste):CR42418 Su(Ste):CR42418 http://flybase.net/reports/FBgn0259849.html non_protein_coding_gene CR42418 CR42418 16-Dec-15 2015_12 FBgn0035730 CG17744 http://flybase.net/reports/FBgn0035730.html protein_coding_gene CG17744 16-Dec-15 2015_12 FBgn0027873 Cpsf100 Cleavage and polyadenylation specificity factor 100 http://flybase.net/reports/FBgn0027873.html protein_coding_gene 0003730=mRNA 3'-UTR binding "0006398=histone mRNA 3'-end processing, 0006379=mRNA cleavage, 0006378=mRNA polyadenylation, 0022008=neurogenesis" 0005847=mRNA cleavage and polyadenylation specificity factor complex "BcDNA:LD14168, CPSF-100, CPSF100, CG1957" "IPR022712=Beta-Casp domain, IPR011108=RNA-metabolising metallo-beta-lactamase, IPR025069=Cleavage and polyadenylation specificity factor 2, C-terminal, IPR001279=Metallo-beta-lactamase, IPR027075=Cleavage and polyadenylation specificity factor subunit 2" CG1957 16-Dec-15 2015_12 ENSDARG00000067915 YLR115W(CFT2) WBGene00017313(cpsf-2) ENSXETG00000010289(CPSF2) ENSMUSG00000041781(Cpsf2) ENSG00000165934(CPSF2) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC14146 I 1.627040655 1.993760598 -0.03319487 -0.553908201 -0.530139553 -0.183899081 FBgn0038207 CG14356 http://flybase.net/reports/FBgn0038207.html protein_coding_gene CG14356 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0013721 per::Dsim\per per http://flybase.net/reports/FBgn0013721.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0051636 CG31636 http://flybase.net/reports/FBgn0051636.html FBgn0031843 protein_coding_gene 0005215=transporter activity 0006810=transport 0005622=intracellular CG13770 "IPR011074=CRAL/TRIO, N-terminal domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251=CRAL-TRIO lipid binding domain" CG31636 16-Dec-15 2015_12 viable DRSC24911 K 0.062480871 -0.35094369 -0.719603161 0.341463281 0.128143483 1.55877849 FBgn0001398 l(1)2Ea lethal (1) 2Ea http://flybase.net/reports/FBgn0001398.html gene "l(1)N5, N7, JA127, l70, l(1)JA127, N3, l(1)N7" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032393 CG12264 http://flybase.net/reports/FBgn0032393.html protein_coding_gene "0031071=cysteine desulfurase activity, 0030170=pyridoxal phosphate binding, 0004123=cystathionine gamma-lyase activity" "0006534=cysteine metabolic process, 0016226=iron-sulfur cluster assembly, 0006523=alanine biosynthetic process" "0005875=microtubule associated complex, 0005737=cytoplasm, 0005739=mitochondrion" "CG12264-PA, IscS homologue" "IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR016454=Cysteine desulfurase, IPR000192=Aminotransferase class V domain, IPR020578=Aminotransferase class-V, pyridoxal-phosphate binding site, IPR010240=Cysteine desulfurase IscS" CG12264 16-Dec-15 2015_12 ENSDARG00000062237(nfs1) YCL017C(NFS1) WBGene00015021(B0205.6) ENSXETG00000007430(NFS1) ENSMUSG00000027618(Nfs1) ENSG00000078872 "viable,locomotor rhythm defective" FBgn0001940 l(2)26Aa lethal (2) 26Aa http://flybase.net/reports/FBgn0001940.html gene l[x] 16-Dec-15 2015_12 FBgn0033368 CG13743 http://flybase.net/reports/FBgn0033368.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport "IPR000253=Forkhead-associated (FHA) domain, IPR013057=Amino acid transporter, transmembrane domain" CG13743 16-Dec-15 2015_12 ENSDARG00000040257(zgc:110221) YEL064C(AVT2) ENSXETG00000008981(SLC38A11) ENSMUSG00000061171(Slc38a11) ENSG00000169507(SLC38A11) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265378 CR44319 http://flybase.net/reports/FBgn0265378.html non_protein_coding_gene CG44319 CR44319 16-Dec-15 2015_12 FBgn0260233 CG42507 http://flybase.net/reports/FBgn0260233.html protein_coding_gene CG42507 16-Dec-15 2015_12 FBgn0027351 anon-93Bb anon-93Bb http://flybase.net/reports/FBgn0027351.html gene 16-Dec-15 2015_12 FBgn0065096 snmRNA:359 small non-messenger RNA 359 http://flybase.net/reports/FBgn0065096.html FBgn0053712 non_protein_coding_gene "CR33712, Dm-359" CR33712 16-Dec-15 2015_12 FBgn0022297 l(1)M37.2 lethal (1) M37.2 http://flybase.net/reports/FBgn0022297.html gene M37.2 16-Dec-15 2015_12 "lethal,recessive" FBgn0038815 CG5466 http://flybase.net/reports/FBgn0038815.html protein_coding_gene 0022008=neurogenesis IPR022207=Genetic suppressor element-like CG5466 16-Dec-15 2015_12 "viable,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0026313 X11L X11L http://flybase.net/reports/FBgn0026313.html "FBgn0030848, FBgn0030849" protein_coding_gene 0050839=cell adhesion molecule binding "0007269=neurotransmitter secretion, 0016080=synaptic vesicle targeting, 0072657=protein localization to membrane, 0048749=compound eye development, 0007163=establishment or maintenance of cell polarity, 0016081=synaptic vesicle docking" "0005886=plasma membrane, 0005737=cytoplasm" "dX11L, dX11, MINT, CG5678, Mint, x11Lalpha, Dmint, CG5675, X11Lalpha, X11-like, X11, X11/Mint, dX11/Mint/Lin-10, Dmint1, x11/Mint" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001478=PDZ domain, IPR006020=PTB/PI domain" CG5675 16-Dec-15 2015_12 "ENSDARG00000060639(apba2),ENSDARG00000014105(LOC100003938),ENSDARG00000063314" WBGene00002999(lin-10) ENSXETG00000016503(APBA2) "ENSMUSG00000024897(Apba1),ENSMUSG00000030519(Apba2)" "visible,increased cell death,viable,fertile" "ommatidium,interommatidial bristle,rhabdomere | ectopicMZ1369,four cone-cell ommatidial precursor cluster,primary pigment cell,ommatidial precursor cluster,eye,eye disc,rhabdomereGMR.PF,lamina neuropil,medulla neuropil" DRSC19958 I 0.928859217 1.661872811 0.563892156 0.639627738 -0.308454285 0.464484843 FBgn0028473 Non1 Novel nucleolar protein 1 http://flybase.net/reports/FBgn0028473.html FBgn0050341 protein_coding_gene 0005525=GTP binding 0090307=mitotic spindle assembly "0005730=nucleolus, 0005634=nucleus" "Non1, LD23830, BcDNA:LD23830, CG8801, CG30341" "IPR006073=GTP binding domain, IPR024926=Nucleolar GTP-binding protein 1, IPR010674=Nucleolar GTP-binding protein 1, Rossman-fold domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR012973=NOG, C-terminal, IPR005225=Small GTP-binding protein domain, IPR031167=OBG-type guanine nucleotide-binding (G) domain" CG8801 16-Dec-15 2015_12 ENSDARG00000018961(gtpbp4) YPL093W(NOG1) WBGene00020297(T07A9.9) ENSXETG00000018097(GTPBP4) ENSMUSG00000021149(Gtpbp4) ENSG00000107937(GTPBP4) FBgn0002701 mdl male diplolethal http://flybase.net/reports/FBgn0002701.html gene 16-Dec-15 2015_12 FBgn0266497 s-123.2 http://flybase.net/reports/FBgn0266497.html gene 16-Dec-15 2015_12 FBgn0267788 CR46119 http://flybase.net/reports/FBgn0267788.html non_protein_coding_gene CR46119 16-Dec-15 2015_12 FBgn0281843 T:nls-Ctif http://flybase.net/reports/FBgn0281843.html engineered_foreign_region 16-Dec-15 2015_12 FBgn0002325 l(3)86Fd lethal (3) 86Fd http://flybase.net/reports/FBgn0002325.html gene l(3)ck4 16-Dec-15 2015_12 lethal FBgn0064138 stalker stalker http://flybase.net/reports/FBgn0064138.html gene 0040023=establishment of nucleus localization stl 16-Dec-15 2015_12 FBgn0032401 Plzf Promyelocytic leukemia zinc finger ortholog http://flybase.net/reports/FBgn0032401.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "0007474=imaginal disc-derived wing vein specification, 0007265=Ras protein signal transduction" "cg6792, CG6792, PLZF, dPLZF" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR011333=POZ domain" CG6792 16-Dec-15 2015_12 WBGene00001324(eor-1) "ENSXETG00000016041(ZNF509),ENSXETG00000009218(MYNN),ENSXETG00000004510(znf366),ENSXETG00000021364(ZBTB11)" "ENSMUSG00000029127(Zbtb49),ENSMUSG00000019826(Zbtb24),ENSMUSG00000037730(Mynn),ENSMUSG00000028952(Zbtb48),ENSMUSG00000013419" "ENSG00000168826(ZBTB49),ENSG00000116809(ZBTB17),ENSG00000114853(ZBTB47),ENSG00000112365(ZBTB24),ENSG00000085274(MYNN)" "partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile" "wing vein,ectopic,supernumerary" DRSC02994 I 1.577750689 1.07770993 0.052826697 0.85433068 -0.126567889 -0.114137754 FBgn0263530 mir-4917 mir-4917 stem loop http://flybase.net/reports/FBgn0263530.html miRNA_gene "dme-mir-4917, CR43515" CR43515 16-Dec-15 2015_12 FBgn0033030 CG1294 http://flybase.net/reports/FBgn0033030.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005714 l(1)TK117 lethal (1) TK117 http://flybase.net/reports/FBgn0005714.html gene l117 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0034742 CG4294 http://flybase.net/reports/FBgn0034742.html protein_coding_gene FBgn0034742 CG4294 16-Dec-15 2015_12 viable FBgn0028685 Rpt4 Regulatory particle triple-A ATPase 4 http://flybase.net/reports/FBgn0028685.html "FBgn0027213, FBgn0029070, FBgn0040197" protein_coding_gene "0005524=ATP binding, 0016787=hydrolase activity, 0001163=RNA polymerase I regulatory region sequence-specific DNA binding, 0016887=ATPase activity" "1901838=positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter, 0022008=neurogenesis, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005875=microtubule associated complex, 0008540=proteasome regulatory particle, base subcomplex, 0005634=nucleus, 0005838=proteasome regulatory particle, 0005737=cytoplasm" "p42D, l(1)G0114, Dm_Rpt4b, CG3455, Rpt4, Dm_Rpt4a, l(1)G0345, l(1)G0227, S10b, Dmp42D" "IPR005937=26S proteasome subunit P45, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG3455 16-Dec-15 2015_12 ENSDARG00000037038(psmc6) YOR259C(RPT4) WBGene00004504(rpt-4) ENSXETG00000008628(psmc6) ENSMUSG00000021832(Psmc6) ENSG00000100519(PSMC6) "large body,lethal,recessive,small body,dominant,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18713 IEK -3.028558953 -3.339096891 -1.185420791 -1.548624083 3.395993992 0.593456199 FBgn0040973 CG16824 http://flybase.net/reports/FBgn0040973.html protein_coding_gene IPR015157=Translation machinery associated TMA7 CG16824 16-Dec-15 2015_12 ENSDARG00000071670(zgc:153700) ENSXETG00000024938(TEgg142n01.1) FBgn0019739 l(1)91-2 lethal (1) 91-2 http://flybase.net/reports/FBgn0019739.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266847 CR45309 http://flybase.net/reports/FBgn0266847.html non_protein_coding_gene CR45309 16-Dec-15 2015_12 FBgn0010669 l(2)10685 lethal (2) 10685 http://flybase.net/reports/FBgn0010669.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011123 l(1)Q85 lethal (1) Q85 http://flybase.net/reports/FBgn0011123.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0000083 AnxB9 Annexin B9 http://flybase.net/reports/FBgn0000083.html protein_coding_gene "0003779=actin binding, 0005509=calcium ion binding, 0005544=calcium-dependent phospholipid binding, 0005515=protein binding, 0030507=spectrin binding, 0005543=phospholipid binding" "0061467=basolateral protein localization, 0010797=regulation of multivesicular body size involved in endosome transport, 0030011=maintenance of cell polarity, 0048190=wing disc dorsal/ventral pattern formation, 0032509=endosome transport via multivesicular body sorting pathway" "0012505=endomembrane system, 0005938=cell cortex" "Annexin, Ann, annexin, CG5730, ANXB9, Annexin IX, Annexin B9, AnxB9, Anx B9, Annexin B9a, AnnIX" "IPR001464=Annexin, IPR018502=Annexin repeat, IPR018252=Annexin repeat, conserved site" CG5730 16-Dec-15 2015_12 viable FBgn0027322 l(1)G0046 lethal (1) G0046 http://flybase.net/reports/FBgn0027322.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051713 Apf diadenosine tetraphosphate hydrolase http://flybase.net/reports/FBgn0051713.html protein_coding_gene 0004081=bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity "IP04585, CG31713" "IPR003565=Bis(5'-nucleosyl)-tetraphosphatase, IPR000086=NUDIX hydrolase domain, IPR015797=NUDIX hydrolase domain-like, IPR020084=NUDIX hydrolase, conserved site" CG31713 16-Dec-15 2015_12 ENSDARG00000058728(nudt2) WBGene00003581(ndx-4) ENSXETG00000002162(nudt2) ENSMUSG00000028443(Nudt2) ENSG00000164978(NUDT2) "viable,fertile" FBgn0026403 Ndg Nidogen/entactin http://flybase.net/reports/FBgn0026403.html "FBgn0033509, FBgn0046316" protein_coding_gene 0005509=calcium ion binding 0007160=cell-matrix adhesion 0005604=basement membrane "ndg, nidogen/entactin, nidogen, Nidogen-like, BEST:CK00552, CT32053, CG12908, Nidogen" "IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR011042=Six-bladed beta-propeller, TolB-like, IPR013032=EGF-like, conserved site, IPR001881=EGF-like calcium-binding domain, IPR009017=Green fluorescent protein, IPR006605=G2 nidogen/fibulin G2F, IPR024731=EGF domain, IPR000033=LDLR class B repeat, IPR003886=NIDO domain, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site, IPR023413=Green fluorescent protein-like" CG12908 16-Dec-15 2015_12 "ENSDARG00000068710(LOC100330039),ENSDARG00000009471(si:ch211-13n20.2),ENSDARG00000060675" WBGene00003738(nid-1) ENSXETG00000016220(NID1) "ENSMUSG00000021806(Nid2),ENSMUSG00000005397(Nid1)" "ENSG00000087303(NID2),ENSG00000116962(NID1)" viable FBgn0086724 GiM Genetic interactor of Moesin http://flybase.net/reports/FBgn0086724.html gene "GIM, Genetic Interactor of dMoesin" 16-Dec-15 2015_12 FBgn0019747 l(1)827 lethal (1) 827 http://flybase.net/reports/FBgn0019747.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051207 CG31207 http://flybase.net/reports/FBgn0051207.html FBgn0038848 protein_coding_gene 0005615=extracellular space "CG7096, CG7096-N" IPR010562=Haemolymph juvenile hormone binding CG31207 16-Dec-15 2015_12 viable FBgn0029930 CG12541 http://flybase.net/reports/FBgn0029930.html protein_coding_gene CG12541 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0002262 l(3)69Aa lethal (3) 69Aa http://flybase.net/reports/FBgn0002262.html gene "rsg24, rose-gespleten region interval 24, l(3)rsg24" 16-Dec-15 2015_12 lethal FBgn0058212 CG40212 http://flybase.net/reports/FBgn0058212.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030685 Graf GRAF ortholog (H. sapiens) http://flybase.net/reports/FBgn0030685.html protein_coding_gene "0005096=GTPase activator activity, 0005543=phospholipid binding" "0007165=signal transduction, 0007266=Rho protein signal transduction" "D-Graf, Q9VXQ2_DROME, Graf, CG8948, GTPase regulator associated with focal adhesion kinase ortholog (H. sapiens)" "IPR008936=Rho GTPase activation protein, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001452=SH3 domain, IPR001849=Pleckstrin homology domain, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR000198=Rho GTPase-activating protein domain" CG8948 16-Dec-15 2015_12 "ENSDARG00000035420(ophn1),ENSDARG00000056619(si:rp71-1p14.10),ENSDARG00000010654" WBGene00020209(T04C9.1) "ENSXETG00000001880(ARHGAP26),ENSXETG00000018852(ARHGAP10),ENSXETG00000005487(),ENSXETG00000005092(OPHN1)" "ENSMUSG00000036452(Arhgap26),ENSMUSG00000037148(Arhgap10)" "ENSG00000145819(ARHGAP26),ENSG00000071205(ARHGAP10)" "viable,fertile" FBgn0044863 MMS-4 MMS-4 http://flybase.net/reports/FBgn0044863.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0032230 lft lowfat http://flybase.net/reports/FBgn0032230.html protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis "0005737=cytoplasm, 0035003=subapical complex" "lowfat, lft, CG13139" IPR029270=Limb expression 1 CG13139 16-Dec-15 2015_12 ENSDARG00000063244(si:ch211-210h11.10) ENSXETG00000014034(LIX1L) ENSMUSG00000049288 ENSG00000152022(LIX1L) "viable,fertile,visible,recessive" "wing,wing blade,wing disc,posterior compartment" FBgn0014931 CG2678 http://flybase.net/reports/FBgn0014931.html protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" "0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis" "0005634=nucleus, 0005829=cytosol" "B, anon-84Eb, transcript B, unnamed" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG2678 16-Dec-15 2015_12 "female fertile,viable" FBgn0032503 CG16825 http://flybase.net/reports/FBgn0032503.html FBgn0063748 protein_coding_gene BcDNA:AT09390 CG16825 16-Dec-15 2015_12 viable FBgn0266565 CR45104 http://flybase.net/reports/FBgn0266565.html non_protein_coding_gene lincRNA.803 CR45104 16-Dec-15 2015_12 FBgn0022210 l(2)k04003 lethal (2) k04003 http://flybase.net/reports/FBgn0022210.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034835 CG3092 http://flybase.net/reports/FBgn0034835.html FBgn0044535 protein_coding_gene anon-WO0140519.90 CG3092 16-Dec-15 2015_12 viable DRSC04336 K 0.453475756 0.110631659 0.056360895 -0.469615307 0.18445314 2.587193803 FBgn0051182 CG31182 http://flybase.net/reports/FBgn0051182.html FBgn0047192 protein_coding_gene BcDNA:LD46351 16-Dec-15 2015_12 DRSC22681 I -0.034657253 -2.40884353 0.256386222 -0.05435962 0.297025618 0.33591759 FBgn0065604 l(2)SH0857 lethal (2) SH0857 http://flybase.net/reports/FBgn0065604.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085511 CR40719 http://flybase.net/reports/FBgn0085511.html FBan0040719 non_protein_coding_gene CG40719 CR40719 16-Dec-15 2015_12 FBgn0024510 dlt discs lost http://flybase.net/reports/FBgn0024510.html "FBgn0052315, FBgn0064128" protein_coding_gene "0046331=lateral inhibition, 0001738=morphogenesis of a polarized epithelium, 0007560=imaginal disc morphogenesis, 0042048=olfactory behavior, 0042127=regulation of cell proliferation" 0005737=cytoplasm "Vanaso, Van, dre1, l(3)dre1, CG1977, DLT, vanaso, l(3)62Ba, lethal(3)62Ba, Dlt, CG32315, Discs Lost, l(3)04276" "IPR028171=Codanin-1, C-terminal domain" CG32315 16-Dec-15 2015_12 ENSDARG00000042261(LOC565314) ENSG00000140326(CDAN1) " embryonic stage -- adult stage , embryonic stage " epithelial cell

" embryonic stage , embryonic stage | cycle 14 " " ectoderm

, embryonic/larval salivary gland

, embryonic/larval foregut

, embryonic/larval hindgut

, embryonic/larval trachea

, furrow canal

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,cell size defective,decreased cell number,increased cell death,partially lethal - majority live,viable,visible" "leg,eye-antennal disc,follicle cell,somatic clone,imaginal disc,embryonic/larval salivary gland,eye,wing disc,wing,crossvein,wing hair,supernumerary,chaeta,trichogen cell" DRSC08705 E 0.42012238 -1.465377717 -1.67811885 0.124838963 0.047645153 0.143941912 FBgn0033696 Cyp6g2 Cyp6g2 http://flybase.net/reports/FBgn0033696.html protein_coding_gene "0004497=monooxygenase activity, 0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" "0017085=response to insecticide, 0055114=oxidation-reduction process" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "6g2, Cyp6G2, CG8859, cytochrome P450" "IPR017972=Cytochrome P450, conserved site, IPR002403=Cytochrome P450, E-class, group IV, IPR001128=Cytochrome P450" CG8859 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "chemical resistant,viable" FBgn0044122 E(rst)B54 E(rst)B54 http://flybase.net/reports/FBgn0044122.html gene 0001745=compound eye morphogenesis B54 16-Dec-15 2015_12 viable eye FBgn0264447 CR43865 http://flybase.net/reports/FBgn0264447.html non_protein_coding_gene CR43865 16-Dec-15 2015_12 FBgn0038475 Keap1 Keap1 http://flybase.net/reports/FBgn0038475.html protein_coding_gene 0003779=actin binding 0006979=response to oxidative stress "0005703=polytene chromosome puff, 0005634=nucleus" "KEAP1, keap1, dKeap1, Nrf-2, CG3962, dkeap-1, dkeap1, dKEAP1" "IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR006652=Kelch repeat type 1, IPR011705=BTB/Kelch-associated, IPR015915=Kelch-type beta propeller" CG3962 16-Dec-15 2015_12 ENSDARG00000016132(keap1a) ENSXETG00000011638(KEAP1) ENSMUSG00000003308(Keap1) ENSG00000079999(KEAP1) "large body,developmental rate defective,oxidative stress response defective,dominant,male limited,long lived" FBgn0011053 l(1)Q6 lethal (1) Q6 http://flybase.net/reports/FBgn0011053.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0053400 5SrRNA:CR33400 5SrRNA:CR33400 http://flybase.net/reports/FBgn0053400.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33400 CR33400 16-Dec-15 2015_12 FBgn0002157 l(2)NS lethal (2) NS http://flybase.net/reports/FBgn0002157.html gene "lethal (2) Nova Scotia, l(2)Nova Scotia" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0002092 l(2)57Bb lethal (2) 57Bb http://flybase.net/reports/FBgn0002092.html gene 16-Dec-15 2015_12 lethal FBgn0266724 Trs20 TRAPP subunit 20 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266724.html "FBgn0044807, FBgn0263604, FBgn0005540, FBgn0036573, FBgn0047077, FBgn0083255" protein_coding_gene "0007224=smoothened signaling pathway, 0007283=spermatogenesis, 0006888=ER to Golgi vesicle-mediated transport, 0033227=dsRNA transport, 0016192=vesicle-mediated transport" 0030008=TRAPP complex "Enhancer of smoDN group B-left, l(3)72Dh, CG5161, lethal (3) 72Dh, Trs20p, E(smoDN)B-left, Trs20, BcDNA:RE62842, Group B-left" "IPR006722=Trafficking protein particle complex subunit 2, IPR011012=Longin-like domain" CG5161 16-Dec-15 2015_12 ENSDARG00000068831(trappc2) YBR254C(TRS20) WBGene00021046(sedl-1) ENSXETG00000027080(trappc2) "ENSMUSG00000079317(Trappc2),ENSMUSG00000007777(0610009B22Rik)" ENSG00000196459(TRAPPC2) DRSC10489 IE 1.911156749 0.051813665 2.805822283 -0.631207322 0.045684172 0.165581332 FBgn0085588 CG41267 http://flybase.net/reports/FBgn0085588.html FBan0041267 protein_coding_gene 16-Dec-15 2015_12 FBgn0259308 EP-19 http://flybase.net/reports/FBgn0259308.html gene EP-(19) 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0266686 CR45176 http://flybase.net/reports/FBgn0266686.html non_protein_coding_gene CR45176 16-Dec-15 2015_12 FBgn0265941 CR44728 http://flybase.net/reports/FBgn0265941.html non_protein_coding_gene lincRNA.129 CR44728 16-Dec-15 2015_12 FBgn0001821 l(1)te lethal (1) tracheae enlarged http://flybase.net/reports/FBgn0001821.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval posterior spiracle,embryonic/larval tracheal system" FBgn0038610 CG7675 http://flybase.net/reports/FBgn0038610.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process 0005829=cytosol "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG7675 16-Dec-15 2015_12 YOR246C() viable DRSC16280 I 1.887519436 0.177421493 0.329185816 0.034602998 -0.090334185 -0.478717547 FBgn0069333 UY536 UY536 http://flybase.net/reports/FBgn0069333.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0038349 AOX3 Aldehyde oxidase 3 http://flybase.net/reports/FBgn0038349.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0050660=flavin adenine dinucleotide binding, 0051537=2 iron, 2 sulfur cluster binding, 0004031=aldehyde oxidase activity, 0016614=oxidoreductase activity, acting on CH-OH group of donors" "0006117=acetaldehyde metabolic process, 0055114=oxidation-reduction process" "CG6045, DmAO3" "IPR002888=[2Fe-2S]-binding, IPR016166=FAD-binding, type 2, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR000674=Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR012675=Beta-grasp domain, IPR005107=CO dehydrogenase flavoprotein, C-terminal, IPR008274=Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR002346=Molybdopterin dehydrogenase, FAD-binding, IPR016208=Aldehyde oxidase/xanthine dehydrogenase, IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2" CG6045 16-Dec-15 2015_12 viable FBgn0013386 anon-100CDa anon-100CDa http://flybase.net/reports/FBgn0013386.html gene "pc870, pCY870" 16-Dec-15 2015_12 FBgn0265314 CR44287 http://flybase.net/reports/FBgn0265314.html non_protein_coding_gene CR44287 16-Dec-15 2015_12 FBgn0001575 l(1)1074-ts lethal (1) 1074 ts http://flybase.net/reports/FBgn0001575.html gene l(1)1074[ts] 16-Dec-15 2015_12 lethal "gastrula embryo,embryonic/larval somatic muscle,embryonic/larval cuticle" FBgn0069169 mcl(3)Z0777 mcl(3)Z0777 http://flybase.net/reports/FBgn0069169.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0029015 l(3)77CDj lethal (3) 77CDj http://flybase.net/reports/FBgn0029015.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,partially lethal - majority die,some die during pharate adult stage" "eye,adult thorax & microchaeta" FBgn0005175 l(2)R lethal of Redfield http://flybase.net/reports/FBgn0005175.html gene lethal (2) of Redfield 16-Dec-15 2015_12 lethal FBgn0069212 hyp-K hyp-K http://flybase.net/reports/FBgn0069212.html gene hyp[K] 16-Dec-15 2015_12 FBgn0019952 Orct Organic cation transporter http://flybase.net/reports/FBgn0019952.html protein_coding_gene 0015101=organic cation transmembrane transporter activity "0006915=apoptotic process, 0055085=transmembrane transport, 0015695=organic cation transport" 0016021=integral component of membrane "CG6331, orct" "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG6331 16-Dec-15 2015_12 "ENSDARG00000071049(si:dkey-119m7.4),ENSDARG00000054690(LOC100001249),ENSDARG00000059166(zgc:153639)" "YML123C(PHO84),YCR098C(GIT1)" "ENSXETG00000016581(),ENSXETG00000016584(slc22a5)" "ENSMUSG00000063652(Slc22a21),ENSMUSG00000018900(Slc22a5),ENSMUSG00000020334(Slc22a4)" ENSG00000172940(SLC22A13) embryonic stage && larval stage && adult stage viable FBgn0027178 l(2)60Af lethal (2) 60Af http://flybase.net/reports/FBgn0027178.html gene "unnamed, Unassigned in Interval 2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0029836 CG5928 http://flybase.net/reports/FBgn0029836.html protein_coding_gene CG5928 16-Dec-15 2015_12 "viable,fertile" FBgn0031483 CG9641 http://flybase.net/reports/FBgn0031483.html protein_coding_gene CG9641 16-Dec-15 2015_12 viable FBgn0039155 Kal1 Kallmann syndrome 1 ortholog http://flybase.net/reports/FBgn0039155.html protein_coding_gene 0030414=peptidase inhibitor activity "0009897=external side of plasma membrane, 0005578=proteinaceous extracellular matrix, 0005576=extracellular region, 0009986=cell surface" "Kal-1, kal-1, DmKal-1, Dmkal, CT19368, Kallmann, CG6173" "IPR003961=Fibronectin type III, IPR013783=Immunoglobulin-like fold, IPR008197=WAP-type 'four-disulfide core' domain" CG6173 16-Dec-15 2015_12 "ENSDARG00000004932(kal1b),ENSDARG00000012896(kal1a)" WBGene00002181(kal-1) "partially lethal - majority die,size defective,viable,fertile" "mouth hooks,median tooth,lateral process,hypostomal sclerite,wing vein L4,submarginal cell,wing vein L2,wing vein L3,wing margin,wing,cephalopharyngeal skeleton" FBgn0065405 l(2)SH1586 lethal (2) SH1586 http://flybase.net/reports/FBgn0065405.html gene l(2)SH2 1586 16-Dec-15 2015_12 "lethal,recessive" FBgn0032000 CG8372 http://flybase.net/reports/FBgn0032000.html protein_coding_gene IPR008496=Protein of unknown function DUF778 CG8372 16-Dec-15 2015_12 "ENSDARG00000056399,ENSDARG00000069589(zgc:110759)" WBGene00019221(H20J04.6) ENSXETG00000020673(TMEM222) ENSMUSG00000028857(Tmem222) ENSG00000186501(TMEM222) viable FBgn0267474 CR45824 http://flybase.net/reports/FBgn0267474.html non_protein_coding_gene CR45824 16-Dec-15 2015_12 FBgn0024243 dsx::fru dsx::fru http://flybase.net/reports/FBgn0024243.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0033750 CG13151 http://flybase.net/reports/FBgn0033750.html protein_coding_gene 0003677=DNA binding "IPR017956=AT hook, DNA-binding motif, IPR029526=PiggyBac transposable element-derived protein" CG13151 16-Dec-15 2015_12 viable FBgn0060874 l(3)S045831 lethal (3) S045831 http://flybase.net/reports/FBgn0060874.html gene 0458/31 16-Dec-15 2015_12 "lethal,recessive" FBgn0061476 Zwilch Zwilch http://flybase.net/reports/FBgn0061476.html "FBgn0036933, FBgn0042214" protein_coding_gene 0005515=protein binding "0007067=mitotic nuclear division, 0007094=mitotic spindle assembly checkpoint, 0007093=mitotic cell cycle checkpoint" "0000776=kinetochore, 0051233=spindle midzone, 0005828=kinetochore microtubule, 1990423=RZZ complex, 0005737=cytoplasm" "CG18639, Zwilch, zwilch, CG18729" "IPR018630=RZZ complex, subunit zwilch" CG18729 16-Dec-15 2015_12 "viable,fertile,female sterile,recessive,mitotic cell cycle defective,meiotic cell cycle defective" anaphase & condensed nuclear chromosome FBgn0060944 l(3)S038307 lethal (3) S038307 http://flybase.net/reports/FBgn0060944.html gene 0383/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0264540 CG43919 http://flybase.net/reports/FBgn0264540.html protein_coding_gene CG43919 16-Dec-15 2015_12 FBgn0040569 CG14310 http://flybase.net/reports/FBgn0040569.html protein_coding_gene CG14310 16-Dec-15 2015_12 FBgn0027052 CHIP CHIP ortholog http://flybase.net/reports/FBgn0027052.html protein_coding_gene "0061630=ubiquitin protein ligase activity, 0046983=protein dimerization activity" 0016567=protein ubiquitination 0030018=Z disc "NM 058093.3, CG5203, dCHIP, CHIP, Chip" "IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011990=Tetratricopeptide-like helical domain, IPR003613=U box domain" CG5203 16-Dec-15 2015_12 ENSDARG00000045228(stub1) WBGene00000500(chn-1) ENSMUSG00000039615(Stub1) ENSG00000103266(STUB1) viable DRSC03282 E 0.26167502 -0.936237011 0.103770339 1.585978191 0.410385317 -1.388925335 FBgn0060752 l(3)S064411a lethal (3) S064411a http://flybase.net/reports/FBgn0060752.html "FBgn0060488, FBgn0060489" gene "l(3)S110303, 1103/03, 1103/05, l(3)S110305a, 0644/11" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262256 mir-959 mir-959 stem loop http://flybase.net/reports/FBgn0262256.html miRNA_gene "0006955=immune response, 0060259=regulation of feeding behavior" "miR-959, dme-miR-959-3p, dme-mir-959, CR42963" CR42963 16-Dec-15 2015_12 viable FBgn0005324 Nu Nude http://flybase.net/reports/FBgn0005324.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "adult head & macrochaeta,adult thorax & macrochaeta" FBgn0060703 l(3)S071502 lethal (3) S071502 http://flybase.net/reports/FBgn0060703.html gene 0715/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0046296 CG11534 http://flybase.net/reports/FBgn0046296.html FBgn0036253 protein_coding_gene 0008270=zinc ion binding 0035556=intracellular signal transduction BEST:GH12489 "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001965=Zinc finger, PHD-type, IPR001841=Zinc finger, RING-type, IPR025258=Putative zinc-RING and/or ribbon" CG11534 16-Dec-15 2015_12 WBGene00017646(F20H11.1) ENSXETG00000023412(def8) ENSMUSG00000001482(Def8) ENSG00000140995(DEF8) viable DRSC09840 EK -0.341392414 -0.524061291 -1.546208576 0.11727658 -1.026181247 -1.536066311 FBgn0267752 CR46083 http://flybase.net/reports/FBgn0267752.html non_protein_coding_gene CR46083 16-Dec-15 2015_12 FBgn0000021 abw abnormal wings http://flybase.net/reports/FBgn0000021.html gene 16-Dec-15 2015_12 "visible,recessive" "wing,wing vein,wing vein L5" FBgn0000952 Fs(2)D10 Female sterile D10 http://flybase.net/reports/FBgn0000952.html gene 16-Dec-15 2015_12 "female sterile,dominant" embryo FBgn0065669 l(2)SH0688 lethal (2) SH0688 http://flybase.net/reports/FBgn0065669.html gene l(2)SH2 0688 16-Dec-15 2015_12 "lethal,recessive" FBgn0263593 Lpin Lipin http://flybase.net/reports/FBgn0263593.html "FBgn0033269, FBgn0062224, FBgn0044466" protein_coding_gene "0003713=transcription coactivator activity, 0008195=phosphatidate phosphatase activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0019217=regulation of fatty acid metabolic process, 0030514=negative regulation of BMP signaling pathway, 0007474=imaginal disc-derived wing vein specification, 0055088=lipid homeostasis, 0019432=triglyceride biosynthetic process, 0042594=response to starvation, 0010565=regulation of cellular ketone metabolic process" "0005634=nucleus, 0005737=cytoplasm, 0035183=female germline ring canal inner rim" "dLipin, DmLpin, unnamed, CG8709, lipin, anon-WO0118547.133, DmLipin, LIPIN, DLpin, EP2431" "IPR007651=Lipin, N-terminal, IPR031315=LNS2/PITP, IPR023214=HAD-like domain, IPR013209=Lipin/Ned1/Smp2 (LNS2)" CG8709 16-Dec-15 2015_12 "ENSDARG00000061214,ENSDARG00000020239(lpin1)" YMR165C(PAH1) WBGene00010425(lpin-1) "ENSXETG00000001617(LPIN2),ENSXETG00000020970(LPIN1)" "ENSMUSG00000024052(Lpin2),ENSMUSG00000020593(Lpin1),ENSMUSG00000027412(Lpin3)" "ENSG00000132793(LPIN3),ENSG00000101577(LPIN2),ENSG00000134324(LPIN1)" FBgn0031257 CG4133 http://flybase.net/reports/FBgn0031257.html protein_coding_gene 0046872=metal ion binding "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG4133 16-Dec-15 2015_12 viable FBgn0023047 l(1)3Ap lethal (1) 3Ap http://flybase.net/reports/FBgn0023047.html gene 1200D2b 16-Dec-15 2015_12 "lethal,recessive" FBgn0005619 Hdc Histidine decarboxylase http://flybase.net/reports/FBgn0005619.html FBgn0044609 protein_coding_gene "0004398=histidine decarboxylase activity, 0030170=pyridoxal phosphate binding" "0042051=compound eye photoreceptor development, 0043052=thermotaxis, 0006520=cellular amino acid metabolic process" "JK910, CG3454, hdc, histidine decarboxylase, anon-WO0140519.259, histidine-decarboxylase" "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR010977=Aromatic-L-amino-acid decarboxylase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR021115=Pyridoxal-phosphate binding site, IPR015424=Pyridoxal phosphate-dependent transferase" CG3454 16-Dec-15 2015_12 ENSXETG00000019831(HDC) ENSMUSG00000027360(Hdc) ENSG00000140287(HDC) adult stage " adult brain cortex

, photoreceptor cell

, retina

, thoracico-abdominal ganglion

" "wild-type,visual behavior defective,recessive,neurophysiology defective,grooming behavior defective,behavior defective,viable,thermotaxis behavior defective,paralytic,heat sensitive" "retina,lobula plate,synaptic vesicle,photoreceptor cell" FBgn0067352 l(3)95EFd lethal (3) 95EFd http://flybase.net/reports/FBgn0067352.html gene 16-Dec-15 2015_12 "lethal,recessive" embryo FBgn0262787 CG43168 http://flybase.net/reports/FBgn0262787.html protein_coding_gene "chr3L_6268776_6270114.0, lincRNA.451" CG43168 16-Dec-15 2015_12 FBgn0040636 CG13255 http://flybase.net/reports/FBgn0040636.html protein_coding_gene CG13255 16-Dec-15 2015_12 "viable,fertile" FBgn0086403 BG02601 http://flybase.net/reports/FBgn0086403.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0030989 Inx5 Innexin 5 http://flybase.net/reports/FBgn0030989.html protein_coding_gene 0005243=gap junction channel activity 0010496=intercellular transport "0005921=gap junction, 0016021=integral component of membrane" "Innexin-5, Dm-inx5, inx5, FBpp0074467, CG7537, innexin 5, inx-5" IPR000990=Innexin CG7537 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" viable FBgn0032700 CG10338 http://flybase.net/reports/FBgn0032700.html protein_coding_gene IPR006968=Root UVB sensitive family CG10338 16-Dec-15 2015_12 ENSDARG00000059919(zgc:162613) ENSXETG00000018831(C16orf58) ENSMUSG00000030780(BC017158) ENSG00000140688(C16orf58) viable FBgn0053383 5SrRNA:CR33383 5SrRNA:CR33383 http://flybase.net/reports/FBgn0053383.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33383 CR33383 16-Dec-15 2015_12 FBgn0043002 Chrac-14 Chromatin accessibility complex 14kD protein http://flybase.net/reports/FBgn0043002.html "FBgn0015712, FBgn0032043, FBgn0040090, FBgn0052956, FBtr0079668, FBpp0079283, FBtr0079669, FBpp0079284, FBtr0079670, FBpp0079285, FBtr0079671, FBpp0079286, FBtr0079672, FBpp0079287" protein_coding_gene "0005515=protein binding, 0046982=protein heterodimerization activity, 0043565=sequence-specific DNA binding, 0070615=nucleosome-dependent ATPase activity, 0004402=histone acetyltransferase activity" "0042766=nucleosome mobilization, 0034080=CENP-A containing nucleosome assembly, 0016573=histone acetylation, 0006338=chromatin remodeling, 0006974=cellular response to DNA damage stimulus, 0071480=cellular response to gamma radiation" "0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0008623=CHRAC" "CHRAC-14, CHRAC14, ESTS:55A11T, chrac-14, CHRAC, 55A11T, CG13399, 13399, Chrac-14, mary, Chrac14, 18K protein, CG32956" "IPR009072=Histone-fold, IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain" CG13399 16-Dec-15 2015_12 ENSDARG00000008551(pole3) WBGene00020823(T26A5.8) ENSMUSG00000028394(Pole3) ENSG00000148229(POLE3) "mitotic cell cycle defective,viable,fertile,eclosion defective,radiation sensitive,DNA repair defective,tumorigenic,flight defective" "chromosomearm.PS,wing" FBgn0052569 TwdlZ TweedleZ http://flybase.net/reports/FBgn0052569.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix CG32569 IPR004145=Domain of unknown function DUF243 CG32569 16-Dec-15 2015_12 viable FBgn0002710 mei-251 meiotic 251 http://flybase.net/reports/FBgn0002710.html gene "0016321=female meiosis chromosome segregation, 0007131=reciprocal meiotic recombination" 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" FBgn0014900 anon-10Ag anon-10Ag http://flybase.net/reports/FBgn0014900.html gene unnamed 16-Dec-15 2015_12 FBgn0084026 CG41465 http://flybase.net/reports/FBgn0084026.html FBan0041465 protein_coding_gene 16-Dec-15 2015_12 FBgn0259644 B1034 http://flybase.net/reports/FBgn0259644.html gene 16-Dec-15 2015_12 visible wing vein FBgn0259996 CR40341 http://flybase.net/reports/FBgn0259996.html "FBgn0058341, FBgn0046674" non_protein_coding_gene "38C.21, anon-38C.21, CG40341" CR40341 16-Dec-15 2015_12 FBgn0004152 l(2)57Af lethal (2) 57Af http://flybase.net/reports/FBgn0004152.html gene 16-Dec-15 2015_12 lethal FBgn0266110 mei-889 meiotic 889 http://flybase.net/reports/FBgn0266110.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female" FBgn0266411 sima similar http://flybase.net/reports/FBgn0266411.html "FBgn0015542, FBgn0011432, FBgn0051031" protein_coding_gene 0046983=protein dimerization activity "0006974=cellular response to DNA damage stimulus, 0030334=regulation of cell migration, 0048477=oogenesis, 0060438=trachea development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0030308=negative regulation of cell growth, 0071456=cellular response to hypoxia, 0006355=regulation of transcription, DNA-templated, 0051726=regulation of cell cycle, 0010508=positive regulation of autophagy, 0032869=cellular response to insulin stimulus, 0045088=regulation of innate immune response" "0005634=nucleus, 0005737=cytoplasm" "SIMA, l(3)j11B7, HIF-1alpha, DMU43090, dHIF-1alpha, bHLHe56, hypoxia-inducible factor-1, Hif-1A, HIF alpha, Sima, dHIF-alpha, Similar, CG45051, CG7951, HIF-alpha, 7951, CG31031, HIF-1, Hypoxia Inducible Factor, HIF-alpha/sima, Hypoxia Inducible Factor ortholog, Hif1alpha" "IPR013767=PAS fold, IPR000014=PAS domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR013655=PAS fold-3, IPR001610=PAC motif" CG45051 16-Dec-15 2015_12 "ENSDARG00000006181(hif1aa),ENSDARG00000034293(hif1ab),ENSDARG00000057671(epas1b),ENSDARG00000008697,ENSDARG00000041169(LOC100330542)" "ENSXETG00000026167(Q6GL61_XENTR),ENSXETG00000014449(HIF1A)" "ENSMUSG00000004328(Hif3a),ENSMUSG00000021109(Hif1a),ENSMUSG00000024140(Epas1)" embryonic stage

ubiquitous FBgn0262890 CG43245 http://flybase.net/reports/FBgn0262890.html protein_coding_gene CG43245 16-Dec-15 2015_12 FBgn0054043 CG34043 http://flybase.net/reports/FBgn0054043.html FBgn0082889 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BP1017, unnamed" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG34043 16-Dec-15 2015_12 FBgn0062599 Mod(var)1474 Mod(var)1474 http://flybase.net/reports/FBgn0062599.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1474 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0040843 CG15213 http://flybase.net/reports/FBgn0040843.html protein_coding_gene CG15213 16-Dec-15 2015_12 viable FBgn0051133 Slimp Seryl-tRNA synthetase-like insect mitochondrial protein http://flybase.net/reports/FBgn0051133.html FBgn0046779 protein_coding_gene "0000049=tRNA binding, 0004828=serine-tRNA ligase activity, 0005524=ATP binding" "0070584=mitochondrion morphogenesis, 0006434=seryl-tRNA aminoacylation, 0045333=cellular respiration" 0005739=mitochondrion "BcDNA:LD24627, SLIMP, CG31133, seryl-tRNA synthetase-like insect mitochondrial protein" "IPR015866=Serine-tRNA synthetase, type1, N-terminal, IPR002317=Serine-tRNA ligase, type1, IPR010978=tRNA-binding arm" CG31133 16-Dec-15 2015_12 "decreased cell number,lethal,heat sensitive,viable" "wing cell,cell autonomous,anterior crossvein,mitochondrion" FBgn0030009 CG15336 http://flybase.net/reports/FBgn0030009.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG15336 16-Dec-15 2015_12 viable FBgn0039993 CG17691 http://flybase.net/reports/FBgn0039993.html FBan0017691 protein_coding_gene 0003863=3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 0046949=fatty-acyl-CoA biosynthetic process 0017086=3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex "IPR029061=Thiamin diphosphate-binding fold, IPR009014=Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II, IPR005475=Transketolase-like, pyrimidine-binding domain" CG17691 16-Dec-15 2015_12 ENSDARG00000014676 WBGene00006518(tag-173) ENSXETG00000011773(BCKDHB) ENSMUSG00000032263(Bckdhb) ENSG00000083123(BCKDHB) viable FBgn0028648 mRpL50 mitochondrial ribosomal protein L50 http://flybase.net/reports/FBgn0028648.html "FBgn0062489, FBgn0063072" protein_coding_gene 0003735=structural constituent of ribosome 0032543=mitochondrial translation 0005762=mitochondrial large ribosomal subunit "anon-65Eb, CG8612, BcDNA:RE06140, ANON-65Eb, MRP-L50, BcDNA:GM06185" "IPR018305=Ribosomal protein L50, mitochondria" CG8612 16-Dec-15 2015_12 WBGene00011883(T21B10.1) ENSMUSG00000044018(Mrpl50) ENSG00000136897(MRPL50) "developmental rate defective,RU486 conditional,short lived,male,female,viable,visible" trichogen cell DRSC11015 K -0.83537068 -1.122024227 0.692639258 0.045240785 -1.580903454 -0.288927931 FBgn0033274 CG14757 http://flybase.net/reports/FBgn0033274.html protein_coding_gene 0005507=copper ion binding "0055070=copper ion homeostasis, 0006121=mitochondrial electron transport, succinate to ubiquinone, 0018293=protein-FAD linkage" 0005739=mitochondrion 146793_at "IPR028882=Succinate dehydrogenase assembly factor 2, mitochondrial, IPR005631=Flavinator of succinate dehydrogenase" CG14757 16-Dec-15 2015_12 ENSDARG00000062971(zgc:163000) YOL071W(EMI5) WBGene00013269(Y57A10A.29) ENSXETG00000006724(SDHAF2) ENSMUSG00000024668(Sdhaf2) ENSG00000167985(SDHAF2) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0053363 5SrRNA-ë¬:CR33363 5SrRNA-ë¬:CR33363 http://flybase.net/reports/FBgn0053363.html pseudogene_attribute CR33363 CR33363 16-Dec-15 2015_12 FBgn0041133 l(2)44Fi lethal (2) 44Fi http://flybase.net/reports/FBgn0041133.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0259840 Su(Ste):CR42409 Su(Ste):CR42409 http://flybase.net/reports/FBgn0259840.html non_protein_coding_gene CR42409 CR42409 16-Dec-15 2015_12 FBgn0262443 mir-286 mir-286 stem loop http://flybase.net/reports/FBgn0262443.html "FBgn0067706, FBgn0262299" miRNA_gene "CR33602, CR43006, Mir-286, 286, mir-286, miR-286" CR43006 16-Dec-15 2015_12 viable FBgn0050163 Cpr60D Cuticular protein 60D http://flybase.net/reports/FBgn0050163.html "FBgn0035045, FBgn0064832" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG4856, cpr60d, BcDNA:RH24125, CG30163" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG30163 16-Dec-15 2015_12 viable FBgn0001990 wek weckle http://flybase.net/reports/FBgn0001990.html "FBgn0027899, FBgn0032571" protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0042803=protein homodimerization activity, 0005515=protein binding, 0008270=zinc ion binding" "0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway, 0006355=regulation of transcription, DNA-templated, 0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded" "0005634=nucleus, 0005886=plasma membrane" "unnamed, BG:DS09217.5, lethal(2)35Ea, l(2)br47, l(2)35Ea, CG4148, l35Ea, Weckle" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG4148 16-Dec-15 2015_12 "visible,recessive,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "leg,wing,embryonic ventral epidermis,germline clone,non-rescuable maternal effect,embryonic/first instar larval cuticle,ventral,filzkorper" FBgn0010920 l(3)07217 lethal (3) 07217 http://flybase.net/reports/FBgn0010920.html gene l(3)02067 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0031379 CG7289 http://flybase.net/reports/FBgn0031379.html protein_coding_gene IPR018795=Protein of unknown function DUF2152 CG7289 16-Dec-15 2015_12 WBGene00015928(C17H12.2) ENSXETG00000013078(KIAA2013) ENSMUSG00000044496(2510039O18Rik) ENSG00000116685(KIAA2013) viable FBgn0005369 vli veins longitudinally shortened http://flybase.net/reports/FBgn0005369.html gene 16-Dec-15 2015_12 "visible,semidominant" "wing vein L2,wing vein L4,wing vein L5" FBgn0015338 CG5861 http://flybase.net/reports/FBgn0015338.html FBgn0020603 protein_coding_gene 0006909=phagocytosis "BG:DS02740.11, unnamed, III, anon-35Fc, anon-35Fa" "IPR019164=Protein of unknown function DUF2053, membrane" CG5861 16-Dec-15 2015_12 ENSDARG00000039913(tmem147) WBGene00022734(ZK418.5) ENSXETG00000006827(TGas054a07.1) ENSMUSG00000006315(Tmem147) ENSG00000105677(TMEM147) " adult stage , embryonic stage " viable FBgn0033287 CG8701 http://flybase.net/reports/FBgn0033287.html FBgn0044549 protein_coding_gene anon-WO0140519.78 "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG8701 16-Dec-15 2015_12 viable FBgn0264745 CR44003 http://flybase.net/reports/FBgn0264745.html "FBgn0085435, FBgn0031511" pseudogene_attribute "CG3485, CG34406-1, CG34406, CG44003" CR44003 16-Dec-15 2015_12 FBgn0050419 CG30419 http://flybase.net/reports/FBgn0050419.html "FBgn0034991, FBgn0034992" protein_coding_gene "CG13573, CG13572" CG30419 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0037743 CG8412 http://flybase.net/reports/FBgn0037743.html protein_coding_gene "0000009=alpha-1,6-mannosyltransferase activity" "0006486=protein glycosylation, 0006488=dolichol-linked oligosaccharide biosynthetic process" 0005783=endoplasmic reticulum "dAlg12, unnamed" IPR005599=GPI mannosyltransferase CG8412 16-Dec-15 2015_12 ENSDARG00000041199(alg12) YNR030W(ALG12) WBGene00022629(ZC513.5) ENSXETG00000025545(ALG12) ENSMUSG00000035845(Alg12) ENSG00000182858(ALG12) viable FBgn0267613 CR45951 http://flybase.net/reports/FBgn0267613.html non_protein_coding_gene CR45951 16-Dec-15 2015_12 FBgn0266789 CR45254 http://flybase.net/reports/FBgn0266789.html non_protein_coding_gene CR45254 16-Dec-15 2015_12 FBgn0020540 l(2)k01015 lethal (2) k01015 http://flybase.net/reports/FBgn0020540.html gene l(2)01015 16-Dec-15 2015_12 "lethal,recessive" FBgn0264984 CR44135 http://flybase.net/reports/FBgn0264984.html non_protein_coding_gene lincRNA.753 CR44135 16-Dec-15 2015_12 FBgn0082585 sprt sprite http://flybase.net/reports/FBgn0082585.html "FBgn0033632, FBgn0050023" protein_coding_gene 0007508=larval heart development "0016023=cytoplasmic membrane-bounded vesicle, 0016328=lateral plasma membrane, 0031252=cell leading edge" "CG30023, CG9026" IPR001478=PDZ domain CG30023 16-Dec-15 2015_12 "viable,fertile" heart primordium FBgn0060883 l(3)S044828 lethal (3) S044828 http://flybase.net/reports/FBgn0060883.html gene 0448/28 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0263446 CR43469 http://flybase.net/reports/FBgn0263446.html non_protein_coding_gene CR43469 16-Dec-15 2015_12 FBgn0262453 mir-275 mir-275 stem loop http://flybase.net/reports/FBgn0262453.html "FBgn0067719, FBgn0262313" miRNA_gene "miR-275, CR43020, dme-mir-275, miR275, mir275, CR33583, 275, dme-miR-275, mir-275" CR43020 16-Dec-15 2015_12 "visible,lethal" "eye,wing,wing vein,spermatocyte cyst" FBgn0035235 CG7879 http://flybase.net/reports/FBgn0035235.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus cg7879 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG7879 16-Dec-15 2015_12 ENSDARG00000057517 WBGene00013703(Y106G6D.7) "ENSXETG00000014694(),ENSXETG00000014696(TEgg001m03.1),ENSXETG00000025920(rbm12)" "ENSMUSG00000038171(Rbm12),ENSMUSG00000046667(Rbm12b),ENSMUSG00000052137(C430048L16Rik)" "ENSG00000183808(RBM12B),ENSG00000214078(CPNE1)" "viable,fertile" FBgn0267538 CR45878 http://flybase.net/reports/FBgn0267538.html non_protein_coding_gene CR45878 16-Dec-15 2015_12 FBgn0031228 ND-15 NADH dehydrogenase (ubiquinone) 15 kDa subunit http://flybase.net/reports/FBgn0031228.html protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NIPM, NADH:ubiquinone oxidoreductase 15 kDa subunit, CG11455, NADH-ubiquinone oxidoreductase 15 kDa subunit, NADH ubiquinone oxidoreductase 15 kDa" "IPR019342=NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5" CG11455 16-Dec-15 2015_12 WBGene00021839(nduf-5) ENSMUSG00000028648(Ndufs5) "viable,visible,flight defective,lethal,heat sensitive" trichogen cell FBgn0036996 mag magro http://flybase.net/reports/FBgn0036996.html protein_coding_gene "0004771=sterol esterase activity, 0004806=triglyceride lipase activity" "0070328=triglyceride homeostasis, 0006629=lipid metabolic process, 0042632=cholesterol homeostasis" 0031410=cytoplasmic vesicle "CG5932, Magro, Mag, lipA" "IPR025483=Lipase, eukaryotic, IPR006693=Partial AB-hydrolase lipase domain, IPR029058=Alpha/Beta hydrolase fold" CG5932 16-Dec-15 2015_12 YKL140W(TGL1) ENSXETG00000009273(lipA) FBgn0036832 CG18223 http://flybase.net/reports/FBgn0036832.html FBgn0063766 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BcDNA:AT03311, SPH200" "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG18223 16-Dec-15 2015_12 viable FBgn0003435 sm smooth http://flybase.net/reports/FBgn0003435.html "FBgn0010597, FBgn0063694" protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0008343=adult feeding behavior, 0008340=determination of adult lifespan, 0007411=axon guidance, 0006397=mRNA processing" "0030529=ribonucleoprotein complex, 0005654=nucleoplasm" "smo, Smooth, BcDNA:GH10856, l(2)05338, CG9218" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006536=HnRNP-L/PTB/hephaestus splicing factor" CG9218 16-Dec-15 2015_12 "ENSDARG00000059303(hnrnpl2),ENSDARG00000035324(hnrpl)" WBGene00016624(C44B7.2) ENSXETG00000000037() "ENSMUSG00000015165(Hnrnpl),ENSMUSG00000024095(Hnrpll)" "ENSG00000104824(HNRNPL),ENSG00000143889(HNRPLL)" "viable,fertile,partially lethal - majority die,lethal,recessive,visible,feeding behavior defective,neuroanatomy defective,short lived,female sterile,male sterile,long lived,some die during pupal stage" "macrochaeta,dorsal,scutellar bristle,microchaeta,abdominal sternite bristle,chemosensory neuron & tibia,macrochaeta & adult abdomen | ventral,acrostichal bristle,trichogen cell" FBgn0050289 CG30289 http://flybase.net/reports/FBgn0050289.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG30289 16-Dec-15 2015_12 WBGene00006621(try-3) "partially lethal - majority die,some die during pupal stage" FBgn0060379 l(3)S135111b lethal (3) S135111b http://flybase.net/reports/FBgn0060379.html gene 1351/11 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0020820 l(3)98Dj lethal (3) 98Dj http://flybase.net/reports/FBgn0020820.html gene M316 16-Dec-15 2015_12 "lethal,recessive" FBgn0063492 GstE8 Glutathione S transferase E8 http://flybase.net/reports/FBgn0063492.html "FBgn0034342, FBgn0061421" protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GST3-2, CG17533, GSTE8, BcDNA:GM08326, DmGSTE8, Gst3-2, gste8" "IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal" CG17533 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0032868 CG17472 http://flybase.net/reports/FBgn0032868.html FBgn0063232 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "BcDNA:GH20534, 38D.23" CG17472 16-Dec-15 2015_12 viable FBgn0085758 CR40639 http://flybase.net/reports/FBgn0085758.html FBan0040639 rRNA_gene CR40639 16-Dec-15 2015_12 FBgn0016049 noy no eye http://flybase.net/reports/FBgn0016049.html gene 16-Dec-15 2015_12 FBgn0065726 l(2)SH0561 lethal (2) SH0561 http://flybase.net/reports/FBgn0065726.html gene l(2)SH2 0561 16-Dec-15 2015_12 "lethal,recessive" FBgn0265607 beat-IIIa beat-IIIa http://flybase.net/reports/FBgn0265607.html "FBgn0032627, FBgn0261815" protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "CG42757, beat IIIa, Beat-IIIa, CG12621" "IPR003599=Immunoglobulin subtype, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG12621 16-Dec-15 2015_12 "ENSDARG00000068114(si:ch211-89p1.1),ENSDARG00000017320(f11r),ENSDARG00000058996,ENSDARG00000061794(jam3),ENSDARG00000063421" FBgn0065689 l(2)SH0646 lethal (2) SH0646 http://flybase.net/reports/FBgn0065689.html gene l(2)SH2 0646 16-Dec-15 2015_12 "lethal,recessive" FBgn0001759 l(1)M9 lethal (1) M9 http://flybase.net/reports/FBgn0001759.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0267536 CR45876 http://flybase.net/reports/FBgn0267536.html non_protein_coding_gene CR45876 16-Dec-15 2015_12 FBgn0069209 krk krake http://flybase.net/reports/FBgn0069209.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic thorax,germline clone,maternal effect,embryo,posterior" FBgn0025766 l(3)89Dd lethal (3) 89Dd http://flybase.net/reports/FBgn0025766.html gene l(3)M175 16-Dec-15 2015_12 "lethal,recessive" FBgn0052806 CG32806 http://flybase.net/reports/FBgn0052806.html FBgn0045393 protein_coding_gene NEST:bs06b11 CG32806 16-Dec-15 2015_12 FBgn0261520 CG32716 http://flybase.net/reports/FBgn0261520.html "FBgn0052716, FBgn0030019" protein_coding_gene CG15339 16-Dec-15 2015_12 FBgn0035538 DopEcR Dopamine/Ecdysteroid receptor http://flybase.net/reports/FBgn0035538.html "FBgn0046593, FBgn0046595" protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0001588=dopamine neurotransmitter receptor activity, coupled via Gs, 0035100=ecdysone binding" "0035075=response to ecdysone, 0008306=associative learning, 0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0071329=cellular response to sucrose stimulus, 0043410=positive regulation of MAPK cascade, 0046959=habituation, 0009267=cellular response to starvation, 0009744=response to sucrose, 0007186=G-protein coupled receptor signaling pathway, 0042594=response to starvation" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "anon-WO0170980.139, DopEcR, DmDopEcR, dop, dopamine/ecdysteroid receptor, CG18314, anon-WO0170980.140" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG18314 16-Dec-15 2015_12 WBGene00010329(F59D12.1) "neurophysiology defective,memory defective,tarsal response defective,chemical conditional,nutrition conditional,courtship behavior defective,male limited,learning defective,RU486 conditional" FBgn0265886 CR44675 http://flybase.net/reports/FBgn0265886.html non_protein_coding_gene CR44675 16-Dec-15 2015_12 FBgn0040652 CG15463 http://flybase.net/reports/FBgn0040652.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024231 grr grater http://flybase.net/reports/FBgn0024231.html gene "0007367=segment polarity determination, 0016055=Wnt signaling pathway" 16-Dec-15 2015_12 FBgn0004030 wx waxy http://flybase.net/reports/FBgn0004030.html gene "wxt, waxtex" 16-Dec-15 2015_12 "male sterile,female fertile,fertile" "wing,1st posterior cell,2nd posterior cell" FBgn0013588 l(3)97Dc lethal (3) 97Dc http://flybase.net/reports/FBgn0013588.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0267594 CR45932 http://flybase.net/reports/FBgn0267594.html pseudogene_attribute CG40583 CR45932 16-Dec-15 2015_12 FBgn0040778 CG17977 http://flybase.net/reports/FBgn0040778.html protein_coding_gene CG17977 16-Dec-15 2015_12 FBgn0013989 Ms(3)R24 Ms(3)R24 http://flybase.net/reports/FBgn0013989.html gene 16-Dec-15 2015_12 FBgn0037778 mtTFB2 mitochondrial transcription factor B2 http://flybase.net/reports/FBgn0037778.html protein_coding_gene "0000179=rRNA (adenine-N6,N6-)-dimethyltransferase activity, 0003712=transcription cofactor activity" "0031167=rRNA methylation, 0006355=regulation of transcription, DNA-templated, 0006390=transcription from mitochondrial promoter, 0006391=transcription initiation from mitochondrial promoter" "0005759=mitochondrial matrix, 0005739=mitochondrion" "TFB2, TFB2M, CG3910, mitochondrial transcription factor b2, d-mtTFB2, d-TF2BM" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR001737=Ribosomal RNA adenine methyltransferase KsgA/Erm, IPR016861=Mitochondrial transcription factor TFB2" CG3910 16-Dec-15 2015_12 ENSMUSG00000026492(Tfb2m) ENSG00000162851(TFB2M) "cell growth defective,viable,poor,developmental rate defective,small body,decreased cell number,increased cell death,lethal - all die before end of larval stage,some die during third instar larval stage" "embryonic/larval brain,wing disc" FBgn0029645 CG14422 http://flybase.net/reports/FBgn0029645.html protein_coding_gene CG14422 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0010163 ms(Y)hd male sterile (Y) hybrid dysgenesis http://flybase.net/reports/FBgn0010163.html gene 16-Dec-15 2015_12 FBgn0069142 mcl(3)Z5121 mcl(3)Z5121 http://flybase.net/reports/FBgn0069142.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0029185 E(Khc)ek10 E(Khc)ek10 http://flybase.net/reports/FBgn0029185.html gene 16-Dec-15 2015_12 FBgn0031602 CG15431 http://flybase.net/reports/FBgn0031602.html protein_coding_gene CG15431 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0014330 l(3)ry84 lethal (3) ry84 http://flybase.net/reports/FBgn0014330.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033187 CG2144 http://flybase.net/reports/FBgn0033187.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR002591=Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase, IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG2144 16-Dec-15 2015_12 YJL062W(LAS21) WBGene00009204(F28C6.4) ENSXETG00000003720(PIGG) ENSMUSG00000029263(Pigg) ENSG00000174227(PIGG) viable FBgn0028563 sut1 sugar transporter 1 http://flybase.net/reports/FBgn0028563.html protein_coding_gene "0005355=glucose transmembrane transporter activity, 0005351=sugar:proton symporter activity" 0055085=transmembrane transport 0016021=integral component of membrane "Sut1, CG8714" "IPR020846=Major facilitator superfamily domain, IPR003663=Sugar/inositol transporter, IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site" CG8714 16-Dec-15 2015_12 YNL318C(HXT14) "viable,fertile,neuroanatomy defective" neurite | pharate adult stage FBgn0032094 CG12439 http://flybase.net/reports/FBgn0032094.html FBgn0061452 protein_coding_gene BcDNA:AT16114 CG12439 16-Dec-15 2015_12 FBgn0002151 l(2)KX3 lethal (2) KX3 http://flybase.net/reports/FBgn0002151.html gene 16-Dec-15 2015_12 lethal FBgn0032997 CG17486 http://flybase.net/reports/FBgn0032997.html "FBan0017486, FBgn0058291" protein_coding_gene 0004066=asparagine synthase (glutamine-hydrolyzing) activity 0006529=asparagine biosynthetic process CG40291 "IPR001962=Asparagine synthase, IPR017932=Glutamine amidotransferase type 2 domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG17486 16-Dec-15 2015_12 ENSDARG00000000540(asnsd1) YML096W() WBGene00010889(M18.3) ENSXETG00000009878(ASNSD1) ENSMUSG00000026095(Asnsd1) ENSG00000138381(ASNSD1) FBgn0024652 l(2)k08625 lethal (2) k08625 http://flybase.net/reports/FBgn0024652.html gene 86/25 16-Dec-15 2015_12 "lethal,recessive" FBgn0083949 CG34113 http://flybase.net/reports/FBgn0083949.html "FBan0014678, FBgn0037392, FBgn0037393, FBgn0037394" protein_coding_gene "CG14677, 34113, CT34460, Dm_3R:9314, CG14678, CG10989" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain, IPR013162=CD80-like, immunoglobulin C2-set" CG34113 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" "visible,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0263267 del2 http://flybase.net/reports/FBgn0263267.html gene 0008406=gonad development delayed gonad formation 2 16-Dec-15 2015_12 "gonad,gonadal sheath proper primordium" FBgn0038658 CG14292 http://flybase.net/reports/FBgn0038658.html protein_coding_gene CG14292 16-Dec-15 2015_12 "viable,fertile" FBgn0266984 CR45435 http://flybase.net/reports/FBgn0266984.html non_protein_coding_gene lincRNA.611 CR45435 16-Dec-15 2015_12 FBgn0267525 CR45865 http://flybase.net/reports/FBgn0267525.html non_protein_coding_gene CR45865 16-Dec-15 2015_12 FBgn0053519 Unc-89 Unc-89 http://flybase.net/reports/FBgn0053519.html "FBgn0034952, FBgn0034953, FBgn0034954, FBgn0034955, FBgn0040499, FBgn0050171, FBgn0050175, FBtr0072198, FBpp0072107, FBpp0072108, FBtr0072200, FBpp0072109" protein_coding_gene "0004672=protein kinase activity, 0005089=Rho guanyl-nucleotide exchange factor activity, 0005524=ATP binding" "0035023=regulation of Rho protein signal transduction, 0045214=sarcomere organization, 0006468=protein phosphorylation, 0007527=adult somatic muscle development" 0031430=M band "CG18019, CG18020, obs, CG3901, obscurin, unc-89, CT12925, BEST:HL01080, CG30171, CG33519, UNC-89, CT40326, Obscurin, CG30175, CT40322, PROJECTIN-like, CG18021" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR007110=Immunoglobulin-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR000219=Dbl homology (DH) domain, IPR020675=Myosin light chain kinase-related, IPR001452=SH3 domain, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG33519 16-Dec-15 2015_12 "ENSDARG00000009567(si:ch211-195m20.1),ENSDARG00000039256(LOC100333138)" WBGene00006820(unc-89) ENSMUSG00000026207(Speg) ENSG00000072195(SPEG) "viable,flightless" "indirect flight muscle,M bandMef2.PR,sarcomere | pharate adult stageMef2.PR,myofibril | adult stageMef2.PR,indirect flight muscle | adult stage,H zone | adult stageMef2.PR,striated muscle thin filament | adult stageMef2.PR,myofibril | adult stageUH3,H zone | adult stageUH3,myofibril | adult stage,M band,H zone,striated muscle thin filament | adult stage" FBgn0021926 l(2)k11201 lethal (2) k11201 http://flybase.net/reports/FBgn0021926.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061009 l(3)S026222b lethal (3) S026222b http://flybase.net/reports/FBgn0061009.html gene 0262/22 16-Dec-15 2015_12 "lethal,recessive" FBgn0044517 ifm(2)RU536 indirect flight muscle (2) RU536 http://flybase.net/reports/FBgn0044517.html gene RU536 16-Dec-15 2015_12 "viable,visible,sterile,partially,recessive,flight defective" "wing,indirect flight muscle" FBgn0034419 CG15111 http://flybase.net/reports/FBgn0034419.html protein_coding_gene "IPR029059=Alpha/beta hydrolase fold-5, IPR029058=Alpha/Beta hydrolase fold" CG15111 16-Dec-15 2015_12 "ENSDARG00000071004(abhd12),ENSDARG00000069828(si:ch211-117n7.7)" WBGene00022393(Y97E10AL.2) ENSXETG00000012789(ABHD12) ENSMUSG00000032046(Abhd12) "ENSG00000100997(ABHD12),ENSG00000131969(ABHD12B)" lethal FBgn0267208 CR45648 http://flybase.net/reports/FBgn0267208.html non_protein_coding_gene CR45648 16-Dec-15 2015_12 FBgn0086340 upd1::upd2 http://flybase.net/reports/FBgn0086340.html engineered_fusion_gene os::upd2 16-Dec-15 2015_12 FBgn0040775 CG12158 http://flybase.net/reports/FBgn0040775.html "FBgn0045890, FBgn0047009" protein_coding_gene 0022008=neurogenesis "anon-WO0153538.61, BcDNA:RH45738" CG12158 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0035848 CG7979 http://flybase.net/reports/FBgn0035848.html protein_coding_gene "0008460=dTDP-glucose 4,6-dehydratase activity" IPR016040=NAD(P)-binding domain CG7979 16-Dec-15 2015_12 ENSDARG00000056102(uxs1) WBGene00005019(sqv-1) ENSXETG00000021671(uxs1) ENSMUSG00000057363(Uxs1) ENSG00000115652(UXS1) viable FBgn0085342 CG34313 http://flybase.net/reports/FBgn0085342.html protein_coding_gene CG4826 CG34313 16-Dec-15 2015_12 ENSXETG00000001143(TNeu038g22.1) FBgn0034636 twz tiwaz http://flybase.net/reports/FBgn0034636.html protein_coding_gene "0051260=protein homooligomerization, 0008049=male courtship behavior, 0002121=inter-male aggressive behavior, 0008344=adult locomotory behavior, 0008343=adult feeding behavior" "Tiwaz, Twz, CG10440" "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR003131=Potassium channel tetramerisation-type BTB domain" CG10440 16-Dec-15 2015_12 "ENSDARG00000045893(kctd15l),ENSDARG00000004192,ENSDARG00000058255" "ENSXETG00000016868(kctd15),ENSXETG00000006930(KCTD1)" "ENSMUSG00000030499(Kctd15),ENSMUSG00000036225(Kctd1)" "ENSG00000134504(KCTD1),ENSG00000153885(KCTD15)" viable FBgn0086069 snoRNA:Me28S-C3351 http://flybase.net/reports/FBgn0086069.html snoRNA_gene "Me28S-Cm3351, CR34698, Me28S-C3351" CR34698 16-Dec-15 2015_12 FBgn0052756 CG32756 http://flybase.net/reports/FBgn0052756.html FBgn0047202 protein_coding_gene 0006302=double-strand break repair 0005634=nucleus BcDNA:LD29716 IPR015381=XLF family CG32756 16-Dec-15 2015_12 ENSG00000187736(NHEJ1) FBgn0039738 Mgat2 Mgat2 http://flybase.net/reports/FBgn0039738.html protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0008455=alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity" "0009312=oligosaccharide biosynthetic process, 0006487=protein N-linked glycosylation" "0016021=integral component of membrane, 0005797=Golgi medial cisterna" "dMGAT2, CG7921, GlcNAcT2, GlcNAc-TII" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR007754=N-acetylglucosaminyltransferase II" CG7921 16-Dec-15 2015_12 ENSDARG00000052408(zgc:162268) WBGene00001645(gly-20) ENSXETG00000009121(mgat2) "viable,fertile" FBgn0015801 Reg-5 Rhythmically expressed gene 5 http://flybase.net/reports/FBgn0015801.html protein_coding_gene 0007623=circadian rhythm "Drosophila Rhythmically expressed gene 5, CG2928, Dreg-5, Dreg, dreg-5, DREG-5, reg-5, Dreg5" CG2928 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0266507 s-409 http://flybase.net/reports/FBgn0266507.html gene 16-Dec-15 2015_12 FBgn0010193 tu-wps tu-wps http://flybase.net/reports/FBgn0010193.html gene 16-Dec-15 2015_12 FBgn0041633 F-element\RTase F element reverse transcriptase http://flybase.net/reports/FBgn0041633.html FBgn0020012 transposable_element_gene "F-ORF2, F\ORF2, ORF2, reverse transcriptase" "IPR000477=Reverse transcriptase domain, IPR005135=Endonuclease/exonuclease/phosphatase" 16-Dec-15 2015_12 " embryonic stage , adult stage && oogenesis stage , embryonic stage | blastoderm " " embryonic/larval foregut

, embryonic central nervous system

, testis

, embryonic/larval salivary gland

, embryonic/larval tracheal system

, nurse cell

,

posterior , amnioserosa

, embryonic/larval muscle system

, follicle cell

" FBgn0037614 CG8116 http://flybase.net/reports/FBgn0037614.html protein_coding_gene "EP(3)3246, GH04517" "IPR019184=Uncharacterised protein family, transmembrane-17" CG8116 16-Dec-15 2015_12 ENSXETG00000023963(TMEM216) "ENSMUSG00000024667(Tmem216),ENSMUSG00000025505(Tmem80)" ENSG00000187049(TMEM216) viable FBgn0261624 I-3 Inhibitor-3 http://flybase.net/reports/FBgn0261624.html FBgn0001560 protein_coding_gene 0008157=protein phosphatase 1 binding "CG11233, CG42707" IPR011107=Protein phosphatase inhibitor CG42707 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0262949 CG43268 http://flybase.net/reports/FBgn0262949.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033668 exp expansion http://flybase.net/reports/FBgn0033668.html protein_coding_gene "0060439=trachea morphogenesis, 0006035=cuticle chitin biosynthetic process, 0006355=regulation of transcription, DNA-templated, 0007185=transmembrane receptor protein tyrosine phosphatase signaling pathway, 0006031=chitin biosynthetic process" "0045177=apical part of cell, 0016020=membrane, 0005737=cytoplasm" CG13188 "IPR001132=SMAD domain, Dwarfin-type, IPR008984=SMAD/FHA domain, IPR017855=SMAD domain-like" CG13188 16-Dec-15 2015_12 WBGene00007935(C34E11.2) lethal DRSC06313 IK -3.064495935 -3.400983671 -1.034571325 0.814511833 4.510866299 6.581515142 FBgn0014198 l(1)14Ce lethal (1) 14Ce http://flybase.net/reports/FBgn0014198.html gene l(1)14Cf 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0267627 CR45965 http://flybase.net/reports/FBgn0267627.html non_protein_coding_gene CR45965 16-Dec-15 2015_12 FBgn0035207 CG9153 http://flybase.net/reports/FBgn0035207.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination" "0005737=cytoplasm, 0005634=nucleus" "NM_167868.1, FBgn0035207" "IPR000408=Regulator of chromosome condensation, RCC1, IPR000569=HECT domain, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG9153 16-Dec-15 2015_12 ENSDARG00000059936(LOC557513) WBGene00021685(Y48G8AL.1) ENSXETG00000023652(HERC3) "ENSMUSG00000020064(Herc4),ENSMUSG00000029804(Herc3)" "ENSG00000148634(HERC4),ENSG00000138641(HERC3)" viable FBgn0031137 CG11230 http://flybase.net/reports/FBgn0031137.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262106 CR42859 http://flybase.net/reports/FBgn0262106.html non_protein_coding_gene CR42859 16-Dec-15 2015_12 FBgn0024912 agt O-6-alkylguanine-DNA alkyltransferase http://flybase.net/reports/FBgn0024912.html protein_coding_gene 0003908=methylated-DNA-[protein]-cysteine S-methyltransferase activity 0006307=DNA dealkylation involved in DNA repair "DmAGT, BG:DS00004.10, CG1303, Agt" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001497=Methylated-DNA-[protein]-cysteine S-methyltransferase, active site, IPR014048=Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding" CG1303 16-Dec-15 2015_12 YDL200C(MGT1) viable DRSC12611 E 0.106768208 0.142452694 1.596707663 -0.001131458 0.221999864 0.865718086 FBgn0002005 l(2)36Bd lethal (2) 36Bd http://flybase.net/reports/FBgn0002005.html gene "l(2L)HT-2, l(2)HT-2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051635 CG31635 http://flybase.net/reports/FBgn0051635.html "FBgn0031840, FBgn0031841, FBgn0047282" protein_coding_gene "CT33252, CG13769, CG13768, BcDNA:GM03875" CG31635 16-Dec-15 2015_12 WBGene00009201(F28C1.3) ENSXETG00000019084(LRRC68) ENSMUSG00000051403(Lrrc68) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0030931 Rad51D Rad51D http://flybase.net/reports/FBgn0030931.html protein_coding_gene "0000150=recombinase activity, 0008094=DNA-dependent ATPase activity" "0006310=DNA recombination, 0051726=regulation of cell cycle, 0006281=DNA repair" "dmRad51D, CG6318, Dm CG6318" IPR027417=P-loop containing nucleoside triphosphate hydrolase CG6318 16-Dec-15 2015_12 ENSG00000196584(XRCC2) viable FBgn0005044 E(var)33AD Enhancer of variegation 33AD http://flybase.net/reports/FBgn0005044.html gene "unnamed, E(var)33A-D" 16-Dec-15 2015_12 FBgn0060427 l(3)S126201 lethal (3) S126201 http://flybase.net/reports/FBgn0060427.html gene 1262/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0265791 CR44580 http://flybase.net/reports/FBgn0265791.html non_protein_coding_gene lincRNA.99 CR44580 16-Dec-15 2015_12 FBgn0265215 fs(2)Z2-1071 http://flybase.net/reports/FBgn0265215.html gene 16-Dec-15 2015_12 female sterile FBgn0025778 fs(3)85Aa fs(3)85Aa http://flybase.net/reports/FBgn0025778.html gene 16-Dec-15 2015_12 FBgn0037900 CG5276 http://flybase.net/reports/FBgn0037900.html protein_coding_gene "0017110=nucleoside-diphosphatase activity, 0005509=calcium ion binding, 0017111=nucleoside-triphosphatase activity" IPR009283=Apyrase CG5276 16-Dec-15 2015_12 "ENSDARG00000016398(LOC100330562),ENSDARG00000012192(cant1a)" WBGene00017244(apy-1) ENSXETG00000020212(Q6P853_XENTR) ENSMUSG00000025575(Cant1) ENSG00000171302(CANT1) viable FBgn0259189 Ir7e Ionotropic receptor 7e http://flybase.net/reports/FBgn0259189.html "FBan0015327, FBgn0029967" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG15327, IR7e, DmelIR7e, CG42293, ionotropic receptor 7e" CG42293 16-Dec-15 2015_12 DRSC18011 I 0.139069486 2.281763043 -0.21270757 0.578926646 -0.32600755 0.245387937 FBgn0035825 CG8111 http://flybase.net/reports/FBgn0035825.html protein_coding_gene IPR012430=Transmembrane protein 43 family CG8111 16-Dec-15 2015_12 ENSXETG00000011540(TMEM43) ENSMUSG00000030095(Tmem43) ENSG00000170876(TMEM43) viable FBgn0030603 CG5541 http://flybase.net/reports/FBgn0030603.html protein_coding_gene 5541 CG5541 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0062523 l(3)88EFi lethal (3) 88EFi http://flybase.net/reports/FBgn0062523.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267673 CR46009 http://flybase.net/reports/FBgn0267673.html non_protein_coding_gene CR46009 16-Dec-15 2015_12 FBgn0265153 CR44222 http://flybase.net/reports/FBgn0265153.html non_protein_coding_gene CR44222 16-Dec-15 2015_12 FBgn0032880 TM9SF2 Transmembrane 9 superfamily protein member 2 http://flybase.net/reports/FBgn0032880.html protein_coding_gene 0061060=negative regulation of peptidoglycan recognition protein signaling pathway "0005737=cytoplasm, 0016021=integral component of membrane, 0005886=plasma membrane" "TM9SF2, 38E.10, CG9318" IPR004240=Nonaspanin (TM9SF) CG9318 16-Dec-15 2015_12 "ENSDARG00000003866(tm9sf2),ENSDARG00000034943(LOC558202)" "YLR083C(EMP70),YDR107C(TMN2)" WBGene00006472(tag-123) ENSXETG00000003479() ENSMUSG00000025544(Tm9sf2) ENSG00000125304(TM9SF2) DRSC03197 IE 2.611157848 1.22374813 -0.15187333 -2.23943471 -0.187120013 0.132843035 FBgn0261618 larp La related protein http://flybase.net/reports/FBgn0261618.html "FBgn0260724, FBgn0040108, FBgn0039579, FBgn0039578, FBgn0047231, FBgn0061128, FBgn0061057" protein_coding_gene "0051225=spindle assembly, 0007140=male meiosis, 0007076=mitotic chromosome condensation, 0000001=mitochondrion inheritance, 0051299=centrosome separation, 0007053=spindle assembly involved in male meiosis, 0035071=salivary gland cell autophagic cell death, 0035186=syncytial blastoderm mitotic cell cycle, 0048102=autophagic cell death" "0005829=cytosol, 0005737=cytoplasm, 0005739=mitochondrion" "l(3)S003108, larp1, dlarp, CG14065, BcDNA:LD02611, lethal (3) S003108, Larp, 0031/08, meteor, lethal (3) S022529, 0225/29, Drosophila La related protein, CG14066, La-related protein, l(3)S022529, CG42551" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR006607=Protein of unknown function DM15, IPR006630=RNA-binding protein Lupus La" CG42551 16-Dec-15 2015_12 WBGene00020097(larp-1) "ENSXETG00000022512(LARP1B),ENSXETG00000008413(LARP1)" ENSMUSG00000037331(Larp1) "ENSG00000155506(LARP1),ENSG00000138709(LARP1B)" FBgn0037883 CG14701 http://flybase.net/reports/FBgn0037883.html protein_coding_gene 0046872=metal ion binding 0017183=peptidyl-diphthamide biosynthetic process from peptidyl-histidine "0005737=cytoplasm, 0005634=nucleus" "IPR007872=Zinc finger, DPH-type" CG14701 16-Dec-15 2015_12 ENSDARG00000043360(zgc:112231) YBL071W-A(KTI11) WBGene00010484(dph-3) ENSXETG00000013835(DPH3) ENSMUSG00000021905(Dph3) ENSG00000154813(DPH3) viable DRSC25545 K 0.290218447 0.242628529 -0.271400905 -0.011221198 0.64787305 2.491559383 FBgn0034523 Nnf1a Nnf1a http://flybase.net/reports/FBgn0034523.html protein_coding_gene "0007059=chromosome segregation, 0007080=mitotic metaphase plate congression" "0031262=Ndc80 complex, 0000776=kinetochore, 0031617=NMS complex" "Nnf1-related protein 2, CG13434, dmNnf1R-2" CG13434 16-Dec-15 2015_12 "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "metaphase,trichogen cell,mesothoracic tergum" FBgn0030257 CG11160 http://flybase.net/reports/FBgn0030257.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression "0005737=cytoplasm, 0005634=nucleus" IPR001214=SET domain CG11160 16-Dec-15 2015_12 viable FBgn0262873 Diedel2 Diedel 2 http://flybase.net/reports/FBgn0262873.html protein_coding_gene 0005615=extracellular space "CG43228, Diedel-2, Chr3R_25434193_25434663.0" IPR025061=Protein of unknown function DUF4002 CG43228 16-Dec-15 2015_12 FBgn0011178 l(1)291-69 lethal (1) 291-69 http://flybase.net/reports/FBgn0011178.html FBgn0010199 gene 291-69 16-Dec-15 2015_12 "lethal,recessive" FBgn0004858 elB elbow B http://flybase.net/reports/FBgn0004858.html FBgn0000569 protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding, 0005515=protein binding" "0035214=eye-antennal disc development, 0001752=compound eye photoreceptor fate commitment, 0007424=open tracheal system development, 0008283=cell proliferation, 0035220=wing disc development, 0035218=leg disc development, 0010629=negative regulation of gene expression, 0007219=Notch signaling pathway, 0048737=imaginal disc-derived appendage development" "0005634=nucleus, 0005730=nucleolus, 0000228=nuclear chromosome" "el, Elbow B, elbowB, BG:DS06238.3, ElbowB, elbow, elb, CG4220, el[B], Elb, P10" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4220 16-Dec-15 2015_12 "ENSDARG00000018492(znf503),ENSDARG00000035563(znf703),ENSDARG00000067720" WBGene00006580(tlp-1) "ENSXETG00000024347(znf503),ENSXETG00000009866(ZNF503)" ENSMUSG00000039081(Zfp503) "ENSG00000183779(ZNF703),ENSG00000165655(ZNF503)" "viable,poor,fertile,visible,recessive,lethal,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" "retina,visceral branch primordium,transverse connective primordium,dorsal branch primordium,eye,adult thorax,dorsocentral bristle,scutellar bristle,supernumerary,ectopic,wing vein,wing,alula,alula & macrochaeta,posterior,wing vein L5,2nd posterior cell,lateral trunk anterior branch,ganglionic branch primordium" DRSC25039 K -0.255914615 0.194802106 0.001762972 -0.120040234 1.56255525 -0.643806941 FBgn0035176 CG13905 http://flybase.net/reports/FBgn0035176.html protein_coding_gene IPR010629=Insect allergen-related CG13905 16-Dec-15 2015_12 viable DRSC08376 I -1.967841342 -0.024815118 -0.599012349 0.307112628 -0.354411661 -1.297281064 FBgn0265377 CR44318 http://flybase.net/reports/FBgn0265377.html non_protein_coding_gene CR44318 16-Dec-15 2015_12 FBgn0011248 ms(3)85D male sterile (3) 85D http://flybase.net/reports/FBgn0011248.html gene 0007286=spermatid development "ms(3)ry85D, ms(3)03565" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0086357 Sec61ë± Sec61 ë± subunit http://flybase.net/reports/FBgn0086357.html "FBgn0026571, FBgn0069450, FBgn0019697, FBgn0031819, FBgn0047201, FBgn0062125, FBgn0062178" protein_coding_gene 0008565=protein transporter activity "0048812=neuron projection morphogenesis, 0010507=negative regulation of autophagy, 0034761=positive regulation of iron ion transmembrane transport, 0008219=cell death, 0098586=cellular response to virus, 0042335=cuticle development, 0006616=SRP-dependent cotranslational protein targeting to membrane, translocation, 0008258=head involution, 0007391=dorsal closure, 0010942=positive regulation of cell death, 0046598=positive regulation of viral entry into host cell" "0012505=endomembrane system, 0005791=rough endoplasmic reticulum, 0005783=endoplasmic reticulum, 0005784=Sec61 translocon complex, 0045169=fusome" "sec61, Sec61, BcDNA:LD29847, sec61alpha, SEC61-alpha, Sec61alpha, dSEC61A, Sec61a, DSec61alpha, LD29847, anon-WO0118547.277, CG9539, l(2)k04917, Sec61-alpha, dSec61alpha, anon-WO0118547.195, effector for neural death and degeneration 2, BEST:LD29847, endd2, 0455, SEC61ALPHA, E(br)165" "IPR019561=Translocon Sec61/SecY, plug domain, IPR030659=SecY conserved site, IPR023201=SecY subunit domain, IPR002208=SecY/SEC61-alpha family" CG9539 16-Dec-15 2015_12 "ENSDARG00000021669(sec61al1),ENSDARG00000005675(sec61al2)" YLR378C(SEC61) WBGene00013311(Y57G11C.15) ENSXETG00000024743(sec61a1) "ENSMUSG00000025816(Sec61a2),ENSMUSG00000030082(Sec61a1)" "ENSG00000065665(SEC61A2),ENSG00000058262(SEC61A1)" DRSC03256 I -0.14783743 -2.165211788 0.816392152 -0.456150298 0.313677613 0.912290545 FBgn0032197 CG5694 http://flybase.net/reports/FBgn0032197.html protein_coding_gene "IPR019525=Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain" CG5694 16-Dec-15 2015_12 "female fertile,viable,female semi-sterile" DRSC02879 IE 1.62044715 -0.327838686 2.031053711 1.083595578 0.397932217 -0.485919662 FBgn0052656 Muc11A Mucin 11A http://flybase.net/reports/FBgn0052656.html FBgn0030371 protein_coding_gene "0005201=extracellular matrix structural constituent, 0008061=chitin binding" 0006030=chitin metabolic process "0005576=extracellular region, 0031012=extracellular matrix" "CG2779, CG32656, Muc11A" IPR002557=Chitin binding domain CG32656 16-Dec-15 2015_12 "ENSXETG00000002633(),ENSXETG00000002634()" viable FBgn0037736 CG12950 http://flybase.net/reports/FBgn0037736.html protein_coding_gene "CT32101, 12950" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain" CG12950 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" viable FBgn0065558 l(2)SH0998 lethal (2) SH0998 http://flybase.net/reports/FBgn0065558.html gene l(2)SH2 0998 16-Dec-15 2015_12 "lethal,recessive" FBgn0085191 CG34162 http://flybase.net/reports/FBgn0085191.html protein_coding_gene CG34162 16-Dec-15 2015_12 FBgn0035413 CG14958 http://flybase.net/reports/FBgn0035413.html protein_coding_gene CG14958 16-Dec-15 2015_12 viable FBgn0038511 CG5873 http://flybase.net/reports/FBgn0038511.html protein_coding_gene "0004601=peroxidase activity, 0020037=heme binding" "0006979=response to oxidative stress, 0055114=oxidation-reduction process" "IPR019791=Haem peroxidase, animal, IPR010255=Haem peroxidase" CG5873 16-Dec-15 2015_12 "ENSDARG00000033280(LOC569363),ENSDARG00000019521(mpx),ENSDARG00000012535" "WBGene00015841(C16C8.2),WBGene00009897(F49E12.1)" ENSXETG00000006966(TPO) "ENSMUSG00000009350(Mpo),ENSMUSG00000052234(Epx),ENSMUSG00000009356(Lpo),ENSMUSG00000020673(Tpo)" ENSG00000115705(TPO) "viable,fertile,visible" mesothoracic tergum FBgn0260396 CG42521 http://flybase.net/reports/FBgn0260396.html FBgn0085266 protein_coding_gene CG34237 CG42521 16-Dec-15 2015_12 FBgn0005291 mei-2199 meiotic 2199 http://flybase.net/reports/FBgn0005291.html gene 2199 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0265673 CR44480 http://flybase.net/reports/FBgn0265673.html non_protein_coding_gene lincRNA.113 CR44480 16-Dec-15 2015_12 FBgn0013256 E(var)31 E(var)31 http://flybase.net/reports/FBgn0013256.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0266616 CR45123 http://flybase.net/reports/FBgn0266616.html non_protein_coding_gene CR45123 16-Dec-15 2015_12 FBgn0030293 CG1737 http://flybase.net/reports/FBgn0030293.html protein_coding_gene 0003677=DNA binding "IPR017956=AT hook, DNA-binding motif" CG1737 16-Dec-15 2015_12 "viable,female fertile" DRSC25132 IEK -1.510745975 -1.068864618 -2.614485252 0.100837421 1.566226248 2.866698462 FBgn0052834 CG32834 http://flybase.net/reports/FBgn0052834.html FBgn0034806 protein_coding_gene "0008236=serine-type peptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "CG30331, SPH196, CG9898" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG32834 16-Dec-15 2015_12 "viable,mating behavior defective,female limited,female semi-sterile" FBgn0084462 W55 W55 http://flybase.net/reports/FBgn0084462.html gene 16-Dec-15 2015_12 "visible,sterile" eye FBgn0004013 whh white head http://flybase.net/reports/FBgn0004013.html gene 16-Dec-15 2015_12 ocellus FBgn0034966 CG13563 http://flybase.net/reports/FBgn0034966.html protein_coding_gene CG13563 16-Dec-15 2015_12 "viable,fertile" DRSC22153 K 0.690905381 0.395710815 0.273329582 0.027887532 -0.486790458 -2.142991791 FBgn0030647 CG6324 http://flybase.net/reports/FBgn0030647.html protein_coding_gene CG6324 16-Dec-15 2015_12 ENSG00000215853(RPTN) viable FBgn0043539 Obp22a Odorant-binding protein 22a http://flybase.net/reports/FBgn0043539.html "FBgn0051941, FBgn0063479" protein_coding_gene 0005549=odorant binding "0007606=sensory perception of chemical stimulus, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "DmelObp22a, Obp-b, obp22, 22a, unnamed, CG31941, anon-AE003584.1" IPR006170=Pheromone/general odorant binding protein CG31941 16-Dec-15 2015_12 viable FBgn0003971 vb vibrissae http://flybase.net/reports/FBgn0003971.html gene 16-Dec-15 2015_12 vibrissae FBgn0034820 CG13538 http://flybase.net/reports/FBgn0034820.html protein_coding_gene CG13538 16-Dec-15 2015_12 viable DRSC04180 I 1.808360946 0.35740203 -0.139231984 -0.229628608 -0.354008741 -0.740237048 FBgn0013695 mt:tRNA:H mitochondrial histidine tRNA http://flybase.net/reports/FBgn0013695.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "CR34084, histidine tRNA, mtdbD00006308" CR34084 16-Dec-15 2015_12 FBgn0065508 l(2)SH1181 lethal (2) SH1181 http://flybase.net/reports/FBgn0065508.html gene l(2)SH2 1181 16-Dec-15 2015_12 "lethal,recessive" FBgn0262624 Tmhs Tetraspan membrane protein in hair cell stereocilia ortholog http://flybase.net/reports/FBgn0262624.html "FBgn0035289, FBgn0002181" protein_coding_gene 0007605=sensory perception of sound "CG12026, TMHS, l(3)62Be, neo7, tetraspan membrane protein in hair cell stereocilia, l(3)neo7, lethal (3) 62Be" IPR019372=Lipoma HMGIC fusion partner-like protein CG12026 16-Dec-15 2015_12 "ENSDARG00000045023,ENSDARG00000056458(zgc:171589),ENSDARG00000021595(lhfpl3)" WBGene00009155(F26D10.11) "ENSXETG00000017857(LHFPL4),ENSXETG00000025680(LHFPL3),ENSXETG00000015464(LHFPL5)" "ENSMUSG00000058361(Lhfpl3),ENSMUSG00000042873(Lhfpl4),ENSMUSG00000062252(Lhfpl5)" "ENSG00000187416(LHFPL3),ENSG00000156959(LHFPL4),ENSG00000197753(LHFPL5)" FBgn0050452 tRNA:CR30452 transfer RNA:CR30452 http://flybase.net/reports/FBgn0050452.html "FBgn0011922, FBgn0050216, FBgn0060140" tRNA_gene "0033436=AUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002787.trna7-MetCAT, tRNA:M3:56EF, transfer RNA:met3:56EF, CR30216, CR30452, tRNA:M:CAT:AE002787-a, tRNA:met3:56EF, chr2R.trna65-MetCAT, tRNA[Met-ATG]" CR30452 16-Dec-15 2015_12 FBgn0003202 rar2 radiation-resistant on 2 http://flybase.net/reports/FBgn0003202.html gene 16-Dec-15 2015_12 FBgn0011867 tRNA:G3:53E transfer RNA:gly3:53E http://flybase.net/reports/FBgn0011867.html "FBgn0050236, FBgn0060217" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Gly-GCC], CR30236, AE002787.trna44-GlyGCC, chr2R.trna27-GlyGCC, tRNA:G:GCC:AE002787-b, tRNA:gly3:53E" CR30236 16-Dec-15 2015_12 FBgn0261853 CG42782 http://flybase.net/reports/FBgn0261853.html protein_coding_gene CG42782 16-Dec-15 2015_12 FBgn0015568 ë±-Est1 ë±-Esterase-1 http://flybase.net/reports/FBgn0015568.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "fragment A, aE1, A, alpha est1, Q9VIC3_DROME, alpha-Est1, alphaE1, DmalphaE1, Alpha-Est1, CG1031, Est1" "IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG1031 16-Dec-15 2015_12 "WBGene00020891(T28C12.4),WBGene00020892(T28C12.5)" viable FBgn0030538 ë_NACtes1 http://flybase.net/reports/FBgn0030538.html protein_coding_gene CG13402 IPR002715=Nascent polypeptide-associated complex NAC domain CG13402 16-Dec-15 2015_12 viable FBgn0000151 awu augenwulst http://flybase.net/reports/FBgn0000151.html gene 16-Dec-15 2015_12 "visible,recessive,viable,good" eye FBgn0060822 l(3)S052111b lethal (3) S052111b http://flybase.net/reports/FBgn0060822.html gene 0521/11 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0015281 Picrotoxin-resistant Picrotoxin-resistant http://flybase.net/reports/FBgn0015281.html gene "PR9, PR38" 16-Dec-15 2015_12 FBgn0265530 CR44380 http://flybase.net/reports/FBgn0265530.html non_protein_coding_gene CR44380 16-Dec-15 2015_12 FBgn0263551 mir-4939 mir-4939 stem loop http://flybase.net/reports/FBgn0263551.html miRNA_gene "CR43536, dme-mir-4939" CR43536 16-Dec-15 2015_12 FBgn0052598 ë_NACtes6 http://flybase.net/reports/FBgn0052598.html protein_coding_gene CG32598 IPR002715=Nascent polypeptide-associated complex NAC domain CG32598 16-Dec-15 2015_12 FBgn0086028 snoRNA:Me28S-G2173 http://flybase.net/reports/FBgn0086028.html snoRNA_gene "Me28S-Gm2173, CR34657, Me28S-G2173" CR34657 16-Dec-15 2015_12 FBgn0002451 l(3)SG4 lethal (3) SG4 http://flybase.net/reports/FBgn0002451.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035359 CG1143 http://flybase.net/reports/FBgn0035359.html protein_coding_gene CG1143 16-Dec-15 2015_12 viable DRSC08188 E 0.715459501 0.608115738 1.761592663 -0.093606337 0.257778352 -0.214001712 FBgn0061160 l(1)7Dp lethal (1) 7Dp http://flybase.net/reports/FBgn0061160.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035827 Srp9 Signal recognition particle protein 9 http://flybase.net/reports/FBgn0035827.html protein_coding_gene "0003729=mRNA binding, 0008312=7S RNA binding" "0045900=negative regulation of translational elongation, 0006614=SRP-dependent cotranslational protein targeting to membrane" "0005786=signal recognition particle, endoplasmic reticulum targeting" "Srp9, CG8268" "IPR008832=Signal recognition particle, SRP9 subunit, IPR009018=Signal recognition particle, SRP9/SRP14 subunit" CG8268 16-Dec-15 2015_12 ENSDARG00000042851(srp9) WBGene00013984(ZK512.4) ENSMUSG00000026511(Srp9) "ENSG00000180581,ENSG00000143742(SRP9)" "viable,visible" mesothoracic tergum FBgn0051997 CG31997 http://flybase.net/reports/FBgn0051997.html "FBgn0043807, FBgn0047106" protein_coding_gene "0005615=extracellular space, 0005829=cytosol" "BcDNA:RE42475, BEST:GH25016" IPR029277=Single domain Von Willebrand factor type C domain CG31997 16-Dec-15 2015_12 viable FBgn0012028 tRNA:Y1:85Ae transfer RNA:tyr1:85Ae http://flybase.net/reports/FBgn0012028.html "FBgn0003849, FBgn0012014, FBgn0051387, FBgn0060001" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA-Tyr, tRNA:tyr1:85Ae, 85Ae, tRNA:Y:GTA:AE002708-e, AE002708.trna61-TyrGTA, chr3R.trna67-TyrGTA, tRNA:Y, Tyr-tRNA, tRNA[Tyr][[1gamma]], tRNA[Tyr], CR31387" CR31387 16-Dec-15 2015_12 FBgn0051646 DIP-ëü Dpr-interacting protein ëü http://flybase.net/reports/FBgn0051646.html "FBgn0031727, FBgn0040948" protein_coding_gene "31646, CG14009, CT33566, CG14008, CG31646, DIP-theta" "IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG31646 16-Dec-15 2015_12 "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000024340(Btnl2),ENSMUSG00000053216(Btn2a2)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" FBgn0044343 springer\gag gag http://flybase.net/reports/FBgn0044343.html transposable_element_gene ORF1 16-Dec-15 2015_12 FBgn0014095 anon-3Ab anon-3Ab http://flybase.net/reports/FBgn0014095.html gene 16-Dec-15 2015_12 embryonic stage--pupal stage FBgn0031585 CG2955 http://flybase.net/reports/FBgn0031585.html FBgn0044702 protein_coding_gene "0008017=microtubule binding, 0005200=structural constituent of cytoskeleton" anon-WO0140519.175 "IPR001715=Calponin homology domain, IPR027328=Microtubule-associated protein RP/EB" CG2955 16-Dec-15 2015_12 viable FBgn0034175 ste24b ste24b prenyl protease type I http://flybase.net/reports/FBgn0034175.html protein_coding_gene 0004222=metalloendopeptidase activity "0007283=spermatogenesis, 0071586=CAAX-box protein processing" 0016020=membrane "prenyl protease type I, Dmel\Ste24, Dmel\Ste24b, CG9001, ste24b" "IPR027057=CAAX prenyl protease 1, IPR001915=Peptidase M48" CG9001 16-Dec-15 2015_12 viable DRSC24340 K 0.196038561 0.488795655 0.131569967 -0.24814698 -0.0485922 -1.511281091 FBgn0002766 mit(1)17 mitotic 17 http://flybase.net/reports/FBgn0002766.html gene 16-Dec-15 2015_12 FBgn0263072 CG43347 http://flybase.net/reports/FBgn0263072.html "FBgn0030219, FBgn0030220, FBgn0047037" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0006351=transcription, DNA-templated" 0005634=nucleus "CG15295, CG9817, BcDNA:RH11383" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR027775=C2H2- zinc finger protein family" CG43347 16-Dec-15 2015_12 FBgn0265298 SC35 http://flybase.net/reports/FBgn0265298.html "FBgn0040286, FBgn0032432, FBgn0040971, FBgn0027696" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0005515=protein binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0031440=regulation of mRNA 3'-end processing, 0000398=mRNA splicing, via spliceosome, 0010468=regulation of gene expression, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0006376=mRNA splice site selection" "0005634=nucleus, 0035062=omega speckle, 0005681=spliceosomal complex, 0016607=nuclear speck, 0000785=chromatin" "CG15494, SC35, dSC35, CG5542, SC-35, CG5442, sc35, anon-EST:Posey284, Sc35, cg5442" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG5442 16-Dec-15 2015_12 "ENSDARG00000010906(zgc:55876),ENSDARG00000057484(srsf2)" WBGene00004701(rsp-4) ENSXETG00000025271(sfrs2) ENSMUSG00000028676(Srsf13a) "ENSG00000161547(SRSF2),ENSG00000214754" FBgn0038655 CG14297 http://flybase.net/reports/FBgn0038655.html protein_coding_gene 0004725=protein tyrosine phosphatase activity 0006470=protein dephosphorylation "0005634=nucleus, 0005737=cytoplasm" LMW-PTP "IPR017867=Protein-tyrosine phosphatase, low molecular weight, IPR023485=Phosphotyrosine protein phosphatase I superfamily" CG14297 16-Dec-15 2015_12 FBgn0083265 E(smoDN)474 Enhancer of smoDN 474 http://flybase.net/reports/FBgn0083265.html gene 16-Dec-15 2015_12 FBgn0022022 l(2)k09005 lethal (2) k09005 http://flybase.net/reports/FBgn0022022.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051446 CG31446 http://flybase.net/reports/FBgn0051446.html FBgn0047110 protein_coding_gene BcDNA:RE40372 "IPR011038=Calycin-like, IPR012674=Calycin" CG31446 16-Dec-15 2015_12 viable FBgn0028944 Semp1 Seminal metalloprotease-1 http://flybase.net/reports/FBgn0028944.html protein_coding_gene "0004222=metalloendopeptidase activity, 0004175=endopeptidase activity, 0008270=zinc ion binding" "0032504=multicellular organism reproduction, 0016485=protein processing, 0006508=proteolysis, 0016477=cell migration" 0005615=extracellular space "BG:BACR44L22.8, BACR44L22.8, semp1, CG11864" "IPR001506=Peptidase M12A, astacin, IPR024079=Metallopeptidase, catalytic domain, IPR006026=Peptidase, metallopeptidase" CG11864 16-Dec-15 2015_12 viable FBgn0065496 l(2)SH1218 lethal (2) SH1218 http://flybase.net/reports/FBgn0065496.html gene l(2)SH2 1218 16-Dec-15 2015_12 "lethal,recessive" FBgn0034713 CG11291 http://flybase.net/reports/FBgn0034713.html protein_coding_gene "0004721=phosphoprotein phosphatase activity, 0016791=phosphatase activity" 0006470=protein dephosphorylation 0005829=cytosol "Phos11291, 22026920" "IPR023214=HAD-like domain, IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR023215=Nitrophenylphosphatase-like domain" CG11291 16-Dec-15 2015_12 YDL236W(PHO13) viable FBgn0032849 mRpS18B mitochondrial ribosomal protein S18B http://flybase.net/reports/FBgn0032849.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "38B.17, mRpS18b, mitochondrial ribosomal protein S18b, MRP-S18-(2), CG10757" IPR001648=Ribosomal protein S18 CG10757 16-Dec-15 2015_12 ENSDARG00000007065(mrps18b) WBGene00011759(T13H5.5) ENSMUSG00000024436(Mrps18b) "ENSG00000203624,ENSG00000204568(MRPS18B),ENSG00000137330" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001429 l(1)6Fb lethal (1) 6Fb http://flybase.net/reports/FBgn0001429.html gene 16-Dec-15 2015_12 lethal FBgn0051568 tRNA:CR31568 transfer RNA:CR31568 http://flybase.net/reports/FBgn0051568.html FBgn0060280 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:A:AGC:AE002708-i, chr3R.trna51-AlaAGC, tRNA[[Ala]], CR31568, AE002708.trna45-AlaAGC" CR31568 16-Dec-15 2015_12 FBgn0265713 CR44520 http://flybase.net/reports/FBgn0265713.html non_protein_coding_gene CR44520 16-Dec-15 2015_12 FBgn0264640 cystic-lumens cystic lumens http://flybase.net/reports/FBgn0264640.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0030049 Trf4-1 http://flybase.net/reports/FBgn0030049.html protein_coding_gene "0003916=DNA topoisomerase activity, 0004652=polynucleotide adenylyltransferase activity, 0003887=DNA-directed DNA polymerase activity" "0043630=ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process, 0007062=sister chromatid cohesion" "AAF46390, DmTRF4-1, CG11265, Trf4" "IPR002934=Polymerase, nucleotidyl transferase domain, IPR002058=PAP/25A-associated" CG11265 16-Dec-15 2015_12 "ENSDARG00000060071(LOC568678),ENSDARG00000062114(papd7)" WBGene00014115(gld-4) ENSXETG00000000446(Q8NDF8-3) "ENSMUSG00000036779(Papd5),ENSMUSG00000034575(Papd7)" "ENSG00000121274(PAPD5),ENSG00000112941(PAPD7)" "visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,viable,fertile" "eye,wing,head | pupal stage,trichogen cell" FBgn0000132 Ars-region10 Autonomous replicating sequence region 10 http://flybase.net/reports/FBgn0000132.html region "HHa240, Ars10, Ars sequence 10" 16-Dec-15 2015_12 FBgn0015558 tty tweety http://flybase.net/reports/FBgn0015558.html protein_coding_gene 0005254=chloride channel activity 0006821=chloride transport "0016021=integral component of membrane, 0005886=plasma membrane" "CG1693, twe, TTYH1" IPR006990=Tweety CG1693 16-Dec-15 2015_12 "ENSDARG00000010727(ttyh2l),ENSDARG00000016934(ttyh2),ENSDARG00000007678(zgc:123242),ENSDARG00000034473(LOC556314)" "ENSXETG00000021763(TTYH3),ENSXETG00000012828(Q6P1U2_XENTR),ENSXETG00000010394(),ENSXETG00000003389()" "ENSMUSG00000034714(Ttyh2),ENSMUSG00000036565(Ttyh3),ENSMUSG00000030428(Ttyh1)" "ENSG00000136295(TTYH3),ENSG00000141540(TTYH2),ENSG00000167614(TTYH1)" viable FBgn0038947 Sar1 Sar1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0038947.html "FBgn0010874, FBgn0025985" protein_coding_gene "0097110=scaffold protein binding, 0005525=GTP binding, 0003924=GTPase activity" "0035050=embryonic heart tube development, 0072661=protein targeting to plasma membrane, 0040003=chitin-based cuticle development, 0009306=protein secretion, 0050775=positive regulation of dendrite morphogenesis, 0070863=positive regulation of protein exit from endoplasmic reticulum, 0003400=regulation of COPII vesicle coating, 0048081=positive regulation of cuticle pigmentation, 0035293=chitin-based larval cuticle pattern formation, 0007029=endoplasmic reticulum organization, 0000902=cell morphogenesis, 0008363=larval chitin-based cuticle development" "0030134=ER to Golgi transport vesicle, 0005811=lipid particle, 0070971=endoplasmic reticulum exit site, 0030127=COPII vesicle coat" "dar3, NP_732719, dendritic arbor reduction 3, dsar1, secretion-associated RAS-related 1, clone 1.48, l(3)05712, 5712, sar1, Sar1, bro5, anon-EST:Liang-1.48, CG7073, Dm Sar1, Q95SY7, SAR1" "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006687=Small GTPase superfamily, SAR1-type" CG7073 16-Dec-15 2015_12 ENSDARG00000033320(sar1a) YPL218W(SAR1) WBGene00022678(sar-1) "ENSXETG00000026979(sara1),ENSXETG00000010408(Q5CZL6_XENTR)" "ENSMUSG00000020386(Sar1b),ENSMUSG00000020088(Sar1a)" "ENSG00000152700(SAR1B),ENSG00000079332(SAR1A)" "lethal,recessive,neuroanatomy defective,cell autonomous,somatic clone,female sterile,germline clone,small body,lethal - all die before end of larval stage,some die during larval stage" "embryonic pericardial cell,cardioblast,dendrite & dendritic arborising neuron,dendrite & dendritic arborising neuron | somatic clone | cell autonomous,dendrite & dorsal multidendritic neuron ddaC | somatic clone | cell autonomous,Golgi apparatus & dendritic arborising neuron | somatic clone | cell autonomous,embryonic/first instar larval cuticle,endoplasmic reticulum | late embryonic stage,embryonic/larval epidermis,sarcomereMef2.PR" FBgn0265710 CR44517 http://flybase.net/reports/FBgn0265710.html non_protein_coding_gene lincRNA.969 CR44517 16-Dec-15 2015_12 FBgn0019949 Cdk9 Cyclin-dependent kinase 9 http://flybase.net/reports/FBgn0019949.html protein_coding_gene "0008353=RNA polymerase II carboxy-terminal domain kinase activity, 0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004693=cyclin-dependent protein serine/threonine kinase activity" "0000278=mitotic cell cycle, 0022008=neurogenesis, 0007155=cell adhesion, 0006368=transcription elongation from RNA polymerase II promoter, 0006468=protein phosphorylation, 0006351=transcription, DNA-templated, 0009408=response to heat, 0008360=regulation of cell shape" "0005634=nucleus, 0005700=polytene chromosome, 0008024=positive transcription elongation factor complex b, 0005703=polytene chromosome puff, 0032783=ELL-EAF complex" "Positive transcription elongation factor b, Positive transcription elongation factor b, small subunit, P-TEFb, PTefb, CDK9, P-TEF, Cyclin-dependent kinase9 2.7, cdk9, p43 PITALRE, positive transcription elongation factor b, CG5179" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG5179 16-Dec-15 2015_12 ENSDARG00000044811(cdk9) WBGene00000410(cdk-9) ENSXETG00000024742(cdk9) ENSMUSG00000009555(Cdk9) ENSG00000136807(CDK9) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC04601 IEK -0.546952694 4.937404282 1.812523158 2.3613096 1.620861677 2.622750373 FBgn0053281 CG33281 http://flybase.net/reports/FBgn0053281.html FBgn0031521 protein_coding_gene 0015145=monosaccharide transmembrane transporter activity "0055085=transmembrane transport, 0015749=monosaccharide transport" "0016020=membrane, 0016021=integral component of membrane" CG15407 "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like" CG33281 16-Dec-15 2015_12 "YDL138W(RGT2),YDL194W(SNF3)" viable FBgn0065560 l(2)SH0996 lethal (2) SH0996 http://flybase.net/reports/FBgn0065560.html gene l(2)SH2 0996 16-Dec-15 2015_12 "lethal,recessive" FBgn0065745 l(2)SH0517 lethal (2) SH0517 http://flybase.net/reports/FBgn0065745.html gene l(2)SH2 0517 16-Dec-15 2015_12 "lethal,recessive" FBgn0266856 CR45317 http://flybase.net/reports/FBgn0266856.html non_protein_coding_gene lincRNA.321 CR45317 16-Dec-15 2015_12 FBgn0012016 tRNA:Y1:22Fa transfer RNA:tyr1:22Fa http://flybase.net/reports/FBgn0012016.html "FBgn0003842, FBgn0012014, FBgn0051987, FBgn0060006" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA-Tyr, tRNA:tyr1:22Fa, tRNA:Y:GTA:AE002638-b, tRNA[Tyr][[1gamma]], Y22Fa, tRNA:Y, AE002638.trna13-TyrGTA, chr2L.trna6-TyrGTA, tRNA[Tyr], CR31987" CR31987 16-Dec-15 2015_12 "viable,fertile,male sterile,female fertile" FBgn0051940 tRNA:CR31940 transfer RNA:CR31940 http://flybase.net/reports/FBgn0051940.html FBgn0060107 tRNA_gene 0033428=CAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:Q:CTG:AE002638-b, AE002638.trna5-GlnCTG, CR31940, chr2L.trna38-GlnCTG" CR31940 16-Dec-15 2015_12 FBgn0021842 l(2)k14817 lethal (2) k14817 http://flybase.net/reports/FBgn0021842.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051577 tRNA:CR31577 transfer RNA:CR31577 http://flybase.net/reports/FBgn0051577.html FBgn0060285 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:A:AGC:AE002708-d, AE002708.trna16-AlaAGC, CR31577, tRNA[[Ala]], chr3R.trna22-AlaAGC" CR31577 16-Dec-15 2015_12 FBgn0032476 CG5439 http://flybase.net/reports/FBgn0032476.html protein_coding_gene 0035091=phosphatidylinositol binding "IPR004012=RUN domain, IPR001683=Phox homologous domain" CG5439 16-Dec-15 2015_12 ENSXETG00000005543() "ENSG00000140660(RUNDC2A),ENSG00000198106,ENSG00000158482" viable FBgn0060428 l(3)S126110b lethal (3) S126110b http://flybase.net/reports/FBgn0060428.html gene 1261/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0004953 1688-11EF 1.688 satellite-related 11EF http://flybase.net/reports/FBgn0004953.html repeat_region 1.688 16-Dec-15 2015_12 FBgn0035014 CG13581 http://flybase.net/reports/FBgn0035014.html FBgn0063767 protein_coding_gene BcDNA:AT03240 CG13581 16-Dec-15 2015_12 viable FBgn0005476 l(1)ts1064 lethal (1) ts1064 http://flybase.net/reports/FBgn0005476.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0029669 CG13021 http://flybase.net/reports/FBgn0029669.html "FBgn0061433, FBgn0064988" protein_coding_gene BcDNA:AT30881 CG13021 16-Dec-15 2015_12 viable FBgn0065878 l(2)SH0239 lethal (2) SH0239 http://flybase.net/reports/FBgn0065878.html gene l(2)SH2 0239 16-Dec-15 2015_12 "lethal,recessive" FBgn0266917 CG16941 http://flybase.net/reports/FBgn0266917.html "FBgn0038464, FBgn0065121" protein_coding_gene 0003723=RNA binding "0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005686=U2 snRNP, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005634=nucleus" "SF3a1, SF3a120, Sf3a1, lethal (3) SH146, l(3)SH146, Splicing factor 3a, subunit 1, l(2)SH3 146" "IPR029071=Ubiquitin-related domain, IPR022030=Splicing factor 3A subunit 1, IPR019956=Ubiquitin, IPR000061=SWAP/Surp, IPR000626=Ubiquitin domain" CG16941 16-Dec-15 2015_12 ENSDARG00000041887(sf3a1) WBGene00004188(prp-21) ENSXETG00000016144(SF3A1) ENSMUSG00000002129(Sf3a1) ENSG00000099995(SF3A1) DRSC15166 EK -0.43346835 0.960820442 -1.434809785 -2.21796498 -1.860759951 -0.634141523 FBgn0262174 mir-993 mir-993 stem loop http://flybase.net/reports/FBgn0262174.html miRNA_gene "CR42881, dme-miR-993, miR-993, dme-mir-993" CR42881 16-Dec-15 2015_12 "lethal,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0261510 cos::Khc http://flybase.net/reports/FBgn0261510.html engineered_fusion_gene kinco 16-Dec-15 2015_12 FBgn0053423 5SrRNA:CR33423 5SrRNA:CR33423 http://flybase.net/reports/FBgn0053423.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33423 CR33423 16-Dec-15 2015_12 FBgn0085354 CG34325 http://flybase.net/reports/FBgn0085354.html protein_coding_gene 0008270=zinc ion binding CG18358 "IPR001781=Zinc finger, LIM-type" CG34325 16-Dec-15 2015_12 WBGene00012379(Y1A5A.1) "ENSXETG00000022912(fhl3),ENSXETG00000002577(FHL2),ENSXETG00000001065(FHL5),ENSXETG00000019760(fhl1)" "ENSMUSG00000032643(Fhl3),ENSMUSG00000008136(Fhl2),ENSMUSG00000028259(Fhl5),ENSMUSG00000050035(Fhl4),ENSMUSG00000023092(Fhl1)" "ENSG00000183386(FHL3),ENSG00000115641(FHL2),ENSG00000112214(FHL5),ENSG00000022267(FHL1)" "viable,fertile" FBgn0065082 snmRNA:782 small non-messenger RNA 782 http://flybase.net/reports/FBgn0065082.html non_protein_coding_gene Dm-782 16-Dec-15 2015_12 FBgn0037239 CG11739 http://flybase.net/reports/FBgn0037239.html "FBan0011739, FBgn0063816" protein_coding_gene 0005371=tricarboxylate secondary active transmembrane transporter activity "0006811=ion transport, 0055085=transmembrane transport" 0016020=membrane anon-EST:Posey55 IPR004686=Tricarboxylate/iron carrier CG11739 16-Dec-15 2015_12 "ENSDARG00000019963(sfxn1),ENSDARG00000057374(sfxn3)" YOR271C(FSF1) "WBGene00011440(sfxn-1.5),WBGene00007080(sfxn-1.1)" "ENSXETG00000018320(sfxn1),ENSXETG00000021403(SFXN3)" "ENSMUSG00000021474(Sfxn1),ENSMUSG00000025212(Sfxn3)" "ENSG00000164466(SFXN1),ENSG00000107819(SFXN3)" "viable,fertile" FBgn0086322 JV212 http://flybase.net/reports/FBgn0086322.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0032682 CG10176 http://flybase.net/reports/FBgn0032682.html protein_coding_gene CG10176 16-Dec-15 2015_12 viable FBgn0265395 Lsd-1::Lsd-2 http://flybase.net/reports/FBgn0265395.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0036015 CG3088 http://flybase.net/reports/FBgn0036015.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH188 "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG3088 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0052786 CG32786 http://flybase.net/reports/FBgn0052786.html protein_coding_gene CG32786 16-Dec-15 2015_12 FBgn0028095 l(3)S074706 lethal (3) S074706 http://flybase.net/reports/FBgn0028095.html gene 0747/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0086613 Ino80 INO80 complex subunit http://flybase.net/reports/FBgn0086613.html "FBgn0051212, FBgn0066103, FBgn0038696, FBgn0038699, FBgn0038703" protein_coding_gene "0000975=regulatory region DNA binding, 0005524=ATP binding, 0004386=helicase activity, 0003677=DNA binding, 0016887=ATPase activity, 0003678=DNA helicase activity" "0006281=DNA repair, 0045892=negative regulation of transcription, DNA-templated, 0010468=regulation of gene expression, 0040034=regulation of development, heterochronic, 0006338=chromatin remodeling" "0000790=nuclear chromatin, 0005634=nucleus, 0031011=Ino80 complex, 0005700=polytene chromosome" "CG18491, CG3602, CG31212, dINO80, INO80, CG14279, dIno80, Ino80, psg25" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR031047=DNA helicase Ino80, IPR020838=DBINO domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain" CG31212 16-Dec-15 2015_12 ENSDARG00000070432(si:ch211-244p18.3) YGL150C(INO80) ENSMUSG00000034154(Ino80) ENSG00000128908(INO80) FBgn0040216 fs(3)BA32 fs(3)BA32 http://flybase.net/reports/FBgn0040216.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0260071 2L2269 http://flybase.net/reports/FBgn0260071.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0261806 CG42752 http://flybase.net/reports/FBgn0261806.html protein_coding_gene CG42752 16-Dec-15 2015_12 FBgn0083015 snoRNA:ë¬18S-920 snoRNA:ë¬18S-920 http://flybase.net/reports/FBgn0083015.html snoRNA_gene "CR34641, psi18S-920, Psi 18S-920" CR34641 16-Dec-15 2015_12 FBgn0038343 Trissin Trissin http://flybase.net/reports/FBgn0038343.html protein_coding_gene 0001664=G-protein coupled receptor binding 0007186=G-protein coupled receptor signaling pathway 0005615=extracellular space "trissin, CG14871" CG14871 16-Dec-15 2015_12 FBgn0000240 bv brevis http://flybase.net/reports/FBgn0000240.html gene bs 16-Dec-15 2015_12 "visible,recessive,viable" macrochaeta FBgn0261933 SmD1 Small ribonucleoprotein particle protein SmD1 http://flybase.net/reports/FBgn0261933.html "FBgn0016940, FBgn0036303, FBgn0047115, FBgn0065180" protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0005829=cytosol, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0005681=spliceosomal complex" "l(2)SH3 003, dD1, CG10753, BcDNA:RE39488, snRNP69D, snRNP-69D, snRNP, smd1, small nuclear ribonucleoprotein at 69D, D1-Sm, lethal (3) SH003, l(3)SH003" "IPR010920=LSM domain, IPR027141=Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3, IPR001163=LSM domain, eukaryotic/archaea-type" CG10753 16-Dec-15 2015_12 ENSDARG00000011648(snrpd1) YGR074W(SMD1) WBGene00004916(snr-3) ENSXETG00000027354(snrpd1) ENSMUSG00000002477(Snrpd1) ENSG00000167088(SNRPD1) DRSC09800 E 1.116502588 1.107503146 2.276599588 0.309721651 -0.188340033 0.241763425 FBgn0026746 anon-25D26Ab anon-25D26Ab http://flybase.net/reports/FBgn0026746.html gene mst 16-Dec-15 2015_12 FBgn0036229 CG7248 http://flybase.net/reports/FBgn0036229.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG7248 16-Dec-15 2015_12 viable FBgn0052099 CG32099 http://flybase.net/reports/FBgn0052099.html FBgn0062499 protein_coding_gene "0000287=magnesium ion binding, 0008897=holo-[acyl-carrier-protein] synthase activity" 0018215=protein phosphopantetheinylation "BcDNA:GH12334, Ebony Activating Protein, EAP, CG32099, eap, ebony activating protein" IPR008278=4'-phosphopantetheinyl transferase superfamily CG32099 16-Dec-15 2015_12 ENSDARG00000037501(zgc:114148) YGL154C(LYS5) "WBGene00020215(T04G9.4),WBGene00012142(T28H10.1)" ENSMUSG00000025894(Aasdhppt) ENSG00000149313(AASDHPPT) DRSC21352 K 0.284940174 0.33597045 0.020639856 -0.551999988 0.735653712 2.250716873 FBgn0032318 CG14072 http://flybase.net/reports/FBgn0032318.html protein_coding_gene CG14072 16-Dec-15 2015_12 FBgn0064170 l(3)3-7E lethal (3) 3-7E http://flybase.net/reports/FBgn0064170.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000790 fs(1)C6 female sterile (1) C6 http://flybase.net/reports/FBgn0000790.html gene 16-Dec-15 2015_12 female sterile "chorion,ovary" FBgn0000213 brb broad abdomen http://flybase.net/reports/FBgn0000213.html gene 16-Dec-15 2015_12 "visible,viable,fertile,recessive,eye color defective" "pigment cell,wing,adult thorax,adult abdomen,macrochaeta,eye" FBgn0036141 wls wntless http://flybase.net/reports/FBgn0036141.html protein_coding_gene 0017147=Wnt-protein binding "0035017=cuticle pattern formation, 0001745=compound eye morphogenesis, 0008587=imaginal disc-derived wing margin morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0007367=segment polarity determination, 0016055=Wnt signaling pathway, 0050714=positive regulation of protein secretion, 0030177=positive regulation of Wnt signaling pathway, 0007480=imaginal disc-derived leg morphogenesis, 0002790=peptide secretion, 0033157=regulation of intracellular protein transport" "0012505=endomembrane system, 0042734=presynaptic membrane, 0005769=early endosome, 0045211=postsynaptic membrane, 0005886=plasma membrane, 0005794=Golgi apparatus, 0030285=integral component of synaptic vesicle membrane, 0070062=extracellular exosome, 0005771=multivesicular body, 0031594=neuromuscular junction" "wntless, Evi, Wls, evi, CG6210, Wntless, Evenness interrupted, wls/evi, Sprinter, wls, srt, Wls/Evi, evenness interrupted, Srt, Evi/Wls, sprinter, Evenness Interrupted" IPR009551=Protein wntless CG6210 16-Dec-15 2015_12 ENSDARG00000009534(wls) WBGene00003246(mig-14) ENSXETG00000012387(GPR177) ENSMUSG00000028173(Wls) ENSG00000116729(WLS) "lethal - all die before end of embryonic stage,germline clone,rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,visible,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,male sterile,lethal,viable,fertile,segment polarity phenotype,maternal effect" "embryonic/first instar larval cuticle,germline clone,rescuable maternal effect,wing margin bristle,somatic clone,wing vein L1,wing,wing margin,leg,arista,adult antennal segment,mesothoracic tergum,testis,ovary,denticle belt,maternal effect,supernumerary,larva,eye" FBgn0011187 l(1)296-8 lethal (1) 296-8 http://flybase.net/reports/FBgn0011187.html FBgn0010201 gene 296-8 16-Dec-15 2015_12 "lethal,recessive" FBgn0053744 snmRNA:430:CR33744 snmRNA:430:CR33744 http://flybase.net/reports/FBgn0053744.html non_protein_coding_gene CR33744 CR33744 16-Dec-15 2015_12 FBgn0010369 espc extra sensory photoreceptor cells http://flybase.net/reports/FBgn0010369.html gene esp 16-Dec-15 2015_12 FBgn0259616 B1505 http://flybase.net/reports/FBgn0259616.html gene 16-Dec-15 2015_12 visible "wing margin bristle,submarginal cell,posterior cell,leg,unguis,antennal segment,arista,wing" FBgn0265666 CR44473 http://flybase.net/reports/FBgn0265666.html non_protein_coding_gene CR44473 16-Dec-15 2015_12 FBgn0038966 pinta prolonged depolarization afterpotential (PDA) is not apparent http://flybase.net/reports/FBgn0038966.html protein_coding_gene "0005501=retinoid binding, 0008431=vitamin E binding" "0016063=rhodopsin biosynthetic process, 0007602=phototransduction" "Pinta, CT33362, Lyso-PA acyltransferase, CG13848" "IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG13848 16-Dec-15 2015_12 "neurophysiology defective,viable" FBgn0086608 CG34112 http://flybase.net/reports/FBgn0086608.html "FBgn0083948, FBgn0084031, FBgn0040686" protein_coding_gene "CG41471, CG14649" CG34112 16-Dec-15 2015_12 FBgn0025799 Su(var)1002 Suppressor of variegation 1002 http://flybase.net/reports/FBgn0025799.html gene Su-var(3)1002 16-Dec-15 2015_12 FBgn0024196 robl roadblock http://flybase.net/reports/FBgn0024196.html FBgn0021950 protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled" "0016319=mushroom body development, 0007018=microtubule-based movement, 0048813=dendrite morphogenesis" "0030286=dynein complex, 0005875=microtubule associated complex, 0005868=cytoplasmic dynein complex, 0005858=axonemal dynein complex" "dynein light chain, CG10751, Roadblock, l(2)k10408, Dynein light chain LC7, dynein, light chain, roadblock-type 2, DLC, LC7, roblk" "IPR016561=Dynein light chain roadblock-type 1/2, IPR004942=Roadblock/LAMTOR2 domain" CG10751 16-Dec-15 2015_12 ENSDARG00000021582(dynlrb1) WBGene00012004(dyrb-1) ENSXETG00000024765(dncl2b) ENSMUSG00000034467(Dynlrb2) ENSG00000168589(DYNLRB2) " embryonic stage , larval stage " "viable,fertile,wild-type,paralytic,posterior,recessive,decreased cell number,somatic clone,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "imaginal disc,segmental nerve,eye,macrochaeta,mitotic cell cycle,mitosis & nuclear chromosome,mitotic anaphase,mitotic telophase,adult mushroom body,somatic clone,dendrite | somatic clone,embryonic/larval mushroom body,class IV dendritic arborizing neuron,dendrite | third instar larval stage,trichogen cell" FBgn0264786 CR44016 http://flybase.net/reports/FBgn0264786.html non_protein_coding_gene lincRNA.974 CR44016 16-Dec-15 2015_12 FBgn0029929 CG4593 http://flybase.net/reports/FBgn0029929.html protein_coding_gene 0022008=neurogenesis IPR008532=Domain of unknown function DUF814 CG4593 16-Dec-15 2015_12 ENSDARG00000021753(ccdc25) YMR132C(JLP2) WBGene00013213(Y54G11A.2) ENSXETG00000024728(FLJ10853) ENSMUSG00000022035(Ccdc25) ENSG00000147419(CCDC25) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0052106 CG32106 http://flybase.net/reports/FBgn0052106.html FBgn0064958 protein_coding_gene "BcDNA:GH24302, mlncRNA69E2" CG32106 16-Dec-15 2015_12 viable FBgn0032337 AstCC Allatostatin double C http://flybase.net/reports/FBgn0032337.html protein_coding_gene 0005179=hormone activity 0065007=biological regulation "ASCC, Ast-CC, CG14920, Allatostatin CC, allatostatin double C, ASTCC" CG14920 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0040510 ACXA ACXA http://flybase.net/reports/FBgn0040510.html "FBgn0004851, FBgn0032460" protein_coding_gene 0004016=adenylate cyclase activity "0009190=cyclic nucleotide biosynthetic process, 0035556=intracellular signal transduction, 0007283=spermatogenesis" 0016021=integral component of membrane "AC, Ac62D, adenylyl cyclase, CG17176, DACXA, AdenylateCyclase A, AC62D, Adenylyl cyclase 62D" "IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG17176 16-Dec-15 2015_12 " adult stage | male && spermatogenesis , adult stage | male , larval stage | late , pupal stage " " spermatocyte

, spermatid | early

" viable DRSC00844 K -0.367789239 0.19537325 -0.298719462 0.192029597 2.086526656 0.074641011 FBgn0040013 CG17164 http://flybase.net/reports/FBgn0040013.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040503 CG7763 http://flybase.net/reports/FBgn0040503.html FBgn0033634 protein_coding_gene 0030246=carbohydrate binding "CK02422A, BEST:CK02422, CK02422a" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG7763 16-Dec-15 2015_12 "ENSDARG00000046092(LOC799269),ENSDARG00000069025,ENSDARG00000035891" "WBGene00020585(clec-178),WBGene00018692(F52E1.2)" ENSXETG00000003141(colec10) "ENSMUSG00000059639(Clec4a4),ENSMUSG00000031495(Cd209d),ENSMUSG00000030148(Clec4a2),ENSMUSG00000043832(Clec4a3),ENSMUSG00000067767(Clec4b2),ENSMUSG00000049037(Clec4a1),ENSMUSG00000030147(Clec4b1),ENSMUSG00000023349(Clec4n),ENSMUSG00000030144(Clec4d)" viable FBgn0265419 CR44331 http://flybase.net/reports/FBgn0265419.html non_protein_coding_gene CR44331 16-Dec-15 2015_12 FBgn0031692 TpnC25D Troponin C at 25D http://flybase.net/reports/FBgn0031692.html "FBgn0025551, FBgn0062999" protein_coding_gene 0005509=calcium ion binding "BcDNA:RE53289, TNC25D, TpnCII, CG6514, TpnC25D, DmTpnCII, TpnC II, anon-EST:Posey103, DmTpnC25D, TnC" "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG6514 16-Dec-15 2015_12 viable FBgn0031906 CG5160 http://flybase.net/reports/FBgn0031906.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0022008=neurogenesis, 0007264=small GTPase mediated signal transduction" 0016020=membrane "IPR020849=Small GTPase superfamily, Ras type, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG5160 16-Dec-15 2015_12 ENSDARG00000017474(zgc:110699) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0004455 DebC Developmental embryonic C http://flybase.net/reports/FBgn0004455.html gene "Deb-C, Deb" 16-Dec-15 2015_12 FBgn0028897 CG4935 http://flybase.net/reports/FBgn0028897.html protein_coding_gene 0005515=protein binding "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "BG:DS02740.2, MET30" "IPR020472=G-protein beta WD-40 repeat, IPR018391=Pyrrolo-quinoline quinone beta-propeller repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG4935 16-Dec-15 2015_12 ENSDARG00000041600(wdr83) WBGene00018014(F33G12.2) ENSXETG00000005598(BC084454.1) ENSMUSG00000005150(Wdr83) ENSG00000123154(WDR83) viable FBgn0052275 CG32275 http://flybase.net/reports/FBgn0052275.html protein_coding_gene 16-Dec-15 2015_12 DRSC22780 I -0.511997249 1.599659307 0.12872382 0.507317532 -1.184750344 -0.588886774 FBgn0058290 CG40290 http://flybase.net/reports/FBgn0058290.html FBan0040290 protein_coding_gene 16-Dec-15 2015_12 FBgn0267651 pre-mod(mdg4)-O http://flybase.net/reports/FBgn0267651.html protein_coding_gene CG45989 CG45989 16-Dec-15 2015_12 FBgn0001572 l(1)55 lethal (1) 55 http://flybase.net/reports/FBgn0001572.html gene 16-Dec-15 2015_12 "lethal,viable,male,poor" FBgn0035111 CG16940 http://flybase.net/reports/FBgn0035111.html protein_coding_gene 0008859=exoribonuclease II activity "0000176=nuclear exosome (RNase complex), 0000177=cytoplasmic exosome (RNase complex)" "IPR012340=Nucleic acid-binding, OB-fold, IPR022966=Ribonuclease II/R, conserved site" CG16940 16-Dec-15 2015_12 ENSDARG00000033259 WBGene00018612(F48E8.6) ENSMUSG00000053333(Dis3l2) FBgn0011887 tRNA:K2:42Aa transfer RNA:lys2:42Aa http://flybase.net/reports/FBgn0011887.html "FBgn0003795, FBgn0011886, FBgn0050312, FBgn0060184" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna6-LysCTT, tRNA:K2, tRNA-Lys, tRNA[Lys][[2]], tRNAlys, AE002769.trna14-LysCTT, tRNA:lys2:42Aa, CR30312, tRNA:K:CTT:AE002769-e, 35SLys" CR30312 16-Dec-15 2015_12 FBgn0085476 CG34447 http://flybase.net/reports/FBgn0085476.html "FBgn0031427, FBan0031684, FBgn0051684" protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" "0006629=lipid metabolic process, 0016042=lipid catabolic process" "CG9966, CG31684" "IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family" CG34447 16-Dec-15 2015_12 FBgn0065243 l(2)SH2147 lethal (2) SH2147 http://flybase.net/reports/FBgn0065243.html gene l(2)SH2 2147 16-Dec-15 2015_12 "lethal,recessive" FBgn0012026 tRNA:Y1:85Ac transfer RNA:tyr1:85Ac http://flybase.net/reports/FBgn0012026.html "FBgn0003849, FBgn0012014, FBgn0051434, FBgn0060003" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:Y:GTA:AE002708-c, Tyr-tRNA T85c, tRNA-Tyr, tRNA[Tyr], AE002708.trna59-TyrGTA, CR31434, tRNA:Y, tRNA:tyr1:85Ac, chr3R.trna65-TyrGTA, tRNA[Tyr][[1gamma]], 85Ac" CR31434 16-Dec-15 2015_12 FBgn0005028 dwh dwarfish http://flybase.net/reports/FBgn0005028.html gene 16-Dec-15 2015_12 visible "wing,eye,leg,adult abdomen,adult thorax" FBgn0261518 l(2)k08617 lethal (2) k08617 http://flybase.net/reports/FBgn0261518.html FBgn0022034 gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034951 CG3860 http://flybase.net/reports/FBgn0034951.html protein_coding_gene 0008142=oxysterol binding "IPR000648=Oxysterol-binding protein, IPR018494=Oxysterol-binding protein, conserved site" CG3860 16-Dec-15 2015_12 "ENSDARG00000013830(osbpl2),ENSDARG00000053804,ENSDARG00000011281(osbpl1a),ENSDARG00000053746" "YHR001W(OSH7),YKR003W(OSH6)" WBGene00008832(obr-2) ENSXETG00000002006(osbpl2) "ENSMUSG00000039050(Osbpl2),ENSMUSG00000044252(Osbpl1a)" "ENSG00000130703(OSBPL2),ENSG00000141447(OSBPL1A)" FBgn0260293 GSd402 http://flybase.net/reports/FBgn0260293.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0039940 CG17165 http://flybase.net/reports/FBgn0039940.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036053 iPLA2-VIA calcium-independent phospholipase A2 VIA http://flybase.net/reports/FBgn0036053.html protein_coding_gene 0047499=calcium-independent phospholipase A2 activity 0006629=lipid metabolic process 0005829=cytosol "CG6718, iPLA2-VIA, phospholipase A[[2]]" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR002641=Patatin/Phospholipase A2-related, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase" CG6718 16-Dec-15 2015_12 ENSDARG00000060921(pla2g6) WBGene00012319(W07A8.2) ENSXETG00000006353(PLA2G6) ENSMUSG00000042632(Pla2g6) ENSG00000184381(PLA2G6) FBgn0016780 anon-79Ba anon-79Ba http://flybase.net/reports/FBgn0016780.html gene "T2 transcription unit, T2" 16-Dec-15 2015_12 FBgn0069168 mcl(3)Z1335 mcl(3)Z1335 http://flybase.net/reports/FBgn0069168.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0250793 ds::ft http://flybase.net/reports/FBgn0250793.html engineered_fusion_gene 16-Dec-15 2015_12 "planar polarity defective,cell non-autonomous,somatic clone" trichome & abdominal tergite | somatic clone | cell non-autonomousë±Tub84B.PL FBgn0086394 BG02181 http://flybase.net/reports/FBgn0086394.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0046328 l(2)38DEa lethal (2) 38DEa http://flybase.net/reports/FBgn0046328.html gene lethal in 38D/E 16-Dec-15 2015_12 FBgn0019737 l(1)91-4 lethal (1) 91-4 http://flybase.net/reports/FBgn0019737.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062595 Mod(var)1539 Mod(var)1539 http://flybase.net/reports/FBgn0062595.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1539 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0024606 olfJ150 olfactory J150 http://flybase.net/reports/FBgn0024606.html gene 16-Dec-15 2015_12 smell perception defective FBgn0004500 fs(1)B4 female sterile (1) B4 http://flybase.net/reports/FBgn0004500.html gene 16-Dec-15 2015_12 FBgn0027547 CG1927 http://flybase.net/reports/FBgn0027547.html "FBgn0027776, FBgn0062082" protein_coding_gene "cDNA A, BcDNA:GH11112, anon-62BCb, anon-WO0118547.340" CG1927 16-Dec-15 2015_12 "viable,fertile" FBgn0065791 l(2)SH0427 lethal (2) SH0427 http://flybase.net/reports/FBgn0065791.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043850 2033 2033 http://flybase.net/reports/FBgn0043850.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 "visible,dominant" "eye,morphogenetic furrow,ommatidium" FBgn0069953 CG41069 http://flybase.net/reports/FBgn0069953.html FBan0041069 protein_coding_gene CG40180 16-Dec-15 2015_12 FBgn0263654 CG43645 http://flybase.net/reports/FBgn0263654.html protein_coding_gene mlncRNA36C10 CG43645 16-Dec-15 2015_12 FBgn0032453 CG6180 http://flybase.net/reports/FBgn0032453.html protein_coding_gene IPR008914=Phosphatidylethanolamine-binding protein PEBP CG6180 16-Dec-15 2015_12 ENSDARG00000042069(pbp) "YLR179C(),YLR178C(TFS1)" WBGene00018218(F40A3.3) ENSXETG00000022375(pebp) "ENSMUSG00000048362(Gm9824),ENSMUSG00000032959(Pebp1),ENSMUSG00000047104(Pbp2)" ENSG00000089220(PEBP1) viable FBgn0030251 CG2145 http://flybase.net/reports/FBgn0030251.html protein_coding_gene "0003723=RNA binding, 0004521=endoribonuclease activity" "0090502=RNA phosphodiester bond hydrolysis, endonucleolytic" Dmel_CG2145 IPR018998=Endoribonuclease XendoU CG2145 16-Dec-15 2015_12 ENSDARG00000044204(zgc:158628) "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0263041 CG43336 http://flybase.net/reports/FBgn0263041.html FBgn0038351 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG5302, SPH73" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG43336 16-Dec-15 2015_12 FBgn0262754 Mst77Y-5ë¬ Male-specific pseudogene 77Y 5 http://flybase.net/reports/FBgn0262754.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0036919 Grasp65 Grasp65 http://flybase.net/reports/FBgn0036919.html protein_coding_gene "0007030=Golgi organization, 0016333=morphogenesis of follicular epithelium, 0007472=wing disc morphogenesis" "0000139=Golgi membrane, 0005795=Golgi stack, 0005783=endoplasmic reticulum, 0005886=plasma membrane, 0005794=Golgi apparatus, 0005798=Golgi-associated vesicle" "dGrasp65, dgrasp, CG7809, GRASP, GRASP65, dGRASP" "IPR024958=GRASP55/65 PDZ-like domain, IPR001478=PDZ domain, IPR007583=GRASP55/65" CG7809 16-Dec-15 2015_12 ENSDARG00000015126(gorasp2) WBGene00021536(Y42H9AR.1) ENSXETG00000018839(GORASP2) ENSMUSG00000014959(Gorasp2) ENSG00000115806(GORASP2) "viable,female sterile,germline clone" "wing,wing disc" FBgn0050356 CG30356 http://flybase.net/reports/FBgn0050356.html protein_coding_gene 0005634=nucleus IPR009071=High mobility group box domain CG30356 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0002247 l(3)68Da lethal (3) 68Da http://flybase.net/reports/FBgn0002247.html gene "rsg8, rose-gespleten region interval 8, l(3)rsg8" 16-Dec-15 2015_12 lethal FBgn0030667 CG15599 http://flybase.net/reports/FBgn0030667.html protein_coding_gene CG15599 16-Dec-15 2015_12 viable FBgn0028032 l(3)S102211 lethal (3) S102211 http://flybase.net/reports/FBgn0028032.html gene 1022/11 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0010311 ms(3)76A ms(3)76A http://flybase.net/reports/FBgn0010311.html gene 16-Dec-15 2015_12 male sterile FBgn0250817 CR40465 http://flybase.net/reports/FBgn0250817.html "FBgn0058465, FBgn0061460" non_protein_coding_gene BcDNA:AT13310 CR40465 16-Dec-15 2015_12 FBgn0267085 CR45529 http://flybase.net/reports/FBgn0267085.html non_protein_coding_gene CR45529 16-Dec-15 2015_12 FBgn0001116 fliF flightless F http://flybase.net/reports/FBgn0001116.html gene 0007629=flight behavior "gmp, gumper" 16-Dec-15 2015_12 "flightless,recessive,jumping defective,partially" "myofibril,Z disc" FBgn0025496 l(3)73Bh lethal (3) 73Bh http://flybase.net/reports/FBgn0025496.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259241 CG42339 http://flybase.net/reports/FBgn0259241.html "FBgn0040851, FBgn0030256" protein_coding_gene "0005044=scavenger receptor activity, 0030247=polysaccharide binding" 0006955=immune response "CG12626, CG15204" "IPR001212=Somatomedin B domain, IPR000884=Thrombospondin type-1 (TSP1) repeat" CG42339 16-Dec-15 2015_12 WBGene00011269(R17.3) ENSMUSG00000032719(Gm106) ENSG00000164764(C8orf84) FBgn0263258 chas chascon http://flybase.net/reports/FBgn0263258.html "FBgn0052556, FBgn0030860, FBgn0030861, FBgn0030862, FBgn0259271" protein_coding_gene "0048104=establishment of body hair or bristle planar orientation, 0007476=imaginal disc-derived wing morphogenesis" "0005927=muscle tendon junction, 0016324=apical plasma membrane" "CG32556, CG12988, EP-631, CG12987, CG12989" CG32556 16-Dec-15 2015_12 FBgn0002244 l(3)68Cf lethal (3) 68Cf http://flybase.net/reports/FBgn0002244.html gene "rose-gespleten region interval 5, rsg5, l(3)rsg5" 16-Dec-15 2015_12 lethal FBgn0266532 T:ctail-arr http://flybase.net/reports/FBgn0266532.html engineered_tag cytoplasmic tail of arr 16-Dec-15 2015_12 FBgn0046666 anon-38C.30 anon-38C.30 http://flybase.net/reports/FBgn0046666.html gene 38C.30 16-Dec-15 2015_12 FBgn0004515 CR Compensatory Response http://flybase.net/reports/FBgn0004515.html gene "cr[+], cr" 16-Dec-15 2015_12 FBgn0058231 CG40231 http://flybase.net/reports/FBgn0058231.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000865 fs(1)M59 female sterile (1) M59 http://flybase.net/reports/FBgn0000865.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0262964 CR43275 http://flybase.net/reports/FBgn0262964.html pseudogene_attribute CR43275 16-Dec-15 2015_12 FBgn0035161 CG13898 http://flybase.net/reports/FBgn0035161.html protein_coding_gene 0005509=calcium ion binding "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG13898 16-Dec-15 2015_12 viable FBgn0015505 l(3)EGX13 lethal (3) EGX13 http://flybase.net/reports/FBgn0015505.html gene 16-Dec-15 2015_12 FBgn0023471 anon-30Fc anon-30Fc http://flybase.net/reports/FBgn0023471.html gene 16-Dec-15 2015_12 FBgn0086421 l(3)CHe lethal (3) CHe http://flybase.net/reports/FBgn0086421.html gene complementation group 7 16-Dec-15 2015_12 "lethal,recessive" FBgn0016875 l(2)39Ah lethal (2) 39Ah http://flybase.net/reports/FBgn0016875.html gene I243 16-Dec-15 2015_12 lethal FBgn0043367 EP1581 BEST:RE35685 http://flybase.net/reports/FBgn0043367.html gene "EP1581, RE35685, BEST:RE35685, EP(X)1581" 16-Dec-15 2015_12 visible "scutellar bristle,trichogen cell,ectopic,tormogen cell" FBgn0031597 CG17612 http://flybase.net/reports/FBgn0031597.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG17612 16-Dec-15 2015_12 WBGene00009448(zfp-2) "viable,fertile" FBgn0031100 CG1504 http://flybase.net/reports/FBgn0031100.html protein_coding_gene "CT3673, 1504" "IPR003591=Leucine-rich repeat, typical subtype, IPR026906=Leucine rich repeat 5, IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat" CG1504 16-Dec-15 2015_12 WBGene00013542(Y75B8A.5) ENSXETG00000012043() viable FBgn0267607 CR45945 http://flybase.net/reports/FBgn0267607.html non_protein_coding_gene CR45945 16-Dec-15 2015_12 FBgn0053826 His2A:CG33826 His2A:CG33826 http://flybase.net/reports/FBgn0053826.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33826 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR002119=Histone H2A" CG33826 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0267020 CR45464 http://flybase.net/reports/FBgn0267020.html non_protein_coding_gene CR45464 16-Dec-15 2015_12 FBgn0005134 l(1)Y80 lethal (1) Y80 http://flybase.net/reports/FBgn0005134.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0050297 tRNA:CR30297 transfer RNA:CR30297 http://flybase.net/reports/FBgn0050297.html FBgn0060200 tRNA_gene 0033433=AUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna11-IleAAT, tRNA:I:AAT:AE002787-b, CR30297, AE002787.trna29-IleAAT" CR30297 16-Dec-15 2015_12 FBgn0067763 l(1)B-56 lethal (1) B-56 http://flybase.net/reports/FBgn0067763.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260371 GSd413 http://flybase.net/reports/FBgn0260371.html gene 16-Dec-15 2015_12 lethal FBgn0062626 Mod(var)1094 Mod(var)1094 http://flybase.net/reports/FBgn0062626.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1094 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0024217 l(2)CA7 lethal (2) CA7 http://flybase.net/reports/FBgn0024217.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035790 Cyp316a1 Cyp316a1 http://flybase.net/reports/FBgn0035790.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG8540, cyp316a1, 316a1" IPR001128=Cytochrome P450 CG8540 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0032250 holn1 hole-in-one http://flybase.net/reports/FBgn0032250.html protein_coding_gene "0006909=phagocytosis, 0048749=compound eye development, 0035220=wing disc development, 0090303=positive regulation of wound healing, 0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0022416=chaeta development, 0042060=wound healing" "0005682=U5 snRNP, 0005634=nucleus" CG5198 IPR003169=GYF domain CG5198 16-Dec-15 2015_12 ENSDARG00000027357(cd2bp2) YHR156C(LIN1) WBGene00006563(teg-1) ENSXETG00000018912(cd2bp2) ENSMUSG00000042502(Cd2bp2) ENSG00000169217(CD2BP2) "lethal,wound healing defective,recessive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,scutellum,macrochaeta,ectopic,supernumerary,trichogen cell,wing vein,wing" FBgn0263396 sqd squid http://flybase.net/reports/FBgn0263396.html "FBgn0053328, FBgn0047283, FBgn0086897, FBgn0003498, FBgn0010257, FBgn0010299, FBgn0011398, FBgn0011413, FBgn0027643, FBgn0040556, FBgn0011363" protein_coding_gene "0003676=nucleic acid binding, 0003730=mRNA 3'-UTR binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0048477=oogenesis, 0009953=dorsal/ventral pattern formation, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0006406=mRNA export from nucleus, 0007314=oocyte anterior/posterior axis specification, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0045451=pole plasm oskar mRNA localization, 0007297=ovarian follicle cell migration, 0017148=negative regulation of translation, 0006405=RNA export from nucleus, 0019094=pole plasm mRNA localization, 0033119=negative regulation of RNA splicing, 0008298=intracellular mRNA localization, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0016325=oocyte microtubule cytoskeleton organization, 0007293=germarium-derived egg chamber formation" "0035062=omega speckle, 0005730=nucleolus, 0000785=chromatin, 0071013=catalytic step 2 spliceosome, 0005703=polytene chromosome puff, 0071011=precatalytic spliceosome, 0030529=ribonucleoprotein complex, 0005737=cytoplasm, 0005634=nucleus" "Sqd, hrp40, l(3)EP3631, RNA-binding protein 3, HRP40, Squid, heterogeneous-nuclear-ribonucleoprotein-87Fb, Rbp3, hnRNP A, SQD, squid, Hrp40, lethal (3) j4B4, Hrb87Fb, BcDNA:GM03761, RRM3, l(3)j4B4, hnRNP 1, Hrb87, CG17791, l(3)j6E3, fs(3)00048, CR33328, CG16901, l(3)j8E7, rrm3" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG16901 16-Dec-15 2015_12 "ENSDARG00000007960(hnrnpab),ENSDARG00000017568(zgc:77052),ENSDARG00000059246(hnrnpd),ENSDARG00000003429(hnrpdl)" WBGene00022235(sqd-1) "ENSMUSG00000029328(Hnrpdl),ENSMUSG00000000568(Hnrnpd),ENSMUSG00000020358(Hnrnpab)" "ENSG00000152795(HNRPDL),ENSG00000138668(HNRNPD),ENSG00000197451(HNRNPAB)" " oogenesis stage , adult stage | female , oogenesis stage && adult stage | female , oogenesis stage | stage S8-14 && adult stage | female " " egg chamber

, ovary

" DRSC29779 IK -1.687615485 -0.023446846 1.446615705 0.478368851 -2.491818654 0.657118281 FBgn0028077 l(3)S086802 lethal (3) S086802 http://flybase.net/reports/FBgn0028077.html gene 0868/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0003456 anon-RNA:A1 anon-RNA:A1 http://flybase.net/reports/FBgn0003456.html non_protein_coding_gene "snRNA-c, small nuclear RNA c" 16-Dec-15 2015_12 FBgn0266970 CR45421 http://flybase.net/reports/FBgn0266970.html non_protein_coding_gene CR45421 16-Dec-15 2015_12 FBgn0065546 l(2)SH1050 lethal (2) SH1050 http://flybase.net/reports/FBgn0065546.html gene l(2)SH2 1050 16-Dec-15 2015_12 "lethal,recessive" FBgn0260300 GSd088 http://flybase.net/reports/FBgn0260300.html gene 16-Dec-15 2015_12 lethal FBgn0058002 ND-AGGG NADH dehydrogenase (ubiquinone) AGGG subunit http://flybase.net/reports/FBgn0058002.html FBan0040002 protein_coding_gene 0005747=mitochondrial respiratory chain complex I "NADH:ubiquinone oxidoreductase AGGG subunit, CG40002, NADH ubiquinone oxidoreductase AGGG" IPR026627=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 CG40002 16-Dec-15 2015_12 ENSDARG00000045490(zgc:73329) ENSXETG00000002668(NDUFB2) ENSMUSG00000002416(Ndufb2) FBgn0038209 CG9722 http://flybase.net/reports/FBgn0038209.html protein_coding_gene 0005102=receptor binding IPR006214=Bax inhibitor 1-related CG9722 16-Dec-15 2015_12 ENSDARG00000055138(zgc:110410) YNL305C() "WBGene00009580(xbx-6),WBGene00006470(tag-120)" "ENSXETG00000014916(TMBIM1),ENSXETG00000020393(FAIM2)" lethal FBgn0044452 Atg2 Autophagy-related 2 http://flybase.net/reports/FBgn0044452.html FBgn0035373 protein_coding_gene "1902350=cellular response to chloroquine, 0035096=larval midgut cell programmed cell death, 0010506=regulation of autophagy, 0035069=larval midgut histolysis, 0042060=wound healing, 0014067=negative regulation of phosphatidylinositol 3-kinase signaling, 0016236=macroautophagy, 0006914=autophagy" 0000407=pre-autophagosomal structure "unnamed, Autophagy-specific gene 2, atg2, CG1241, EP3697, ATG2" "IPR026849=Autophagy-related protein 2, IPR015412=Autophagy-related, C-terminal, IPR026854=Vacuolar protein sorting-associated protein 13A, N-terminal domain" CG1241 16-Dec-15 2015_12 ENSDARG00000062912 WBGene00019748(atg-2) ENSXETG00000013953(ATG2B) "ENSMUSG00000024773(Atg2a),ENSMUSG00000041341(Atg2b)" "ENSG00000110046(ATG2A),ENSG00000066739(ATG2B)" pupal stage salivary gland

"neuroanatomy defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "neuromuscular junction,NMJ bouton,anterior fascicle & synapse,intersegmental nerve,embryonic/larval midgut,embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0050343 CG30343 http://flybase.net/reports/FBgn0050343.html FBgn0047277 protein_coding_gene 0000213=tRNA-intron endonuclease activity "0006388=tRNA splicing, via endonucleolytic cleavage and ligation" BcDNA:GM04716 "IPR018593=tRNA-splicing endonuclease subunit Sen15, IPR006677=tRNA intron endonuclease, catalytic domain-like" CG30343 16-Dec-15 2015_12 viable FBgn0040887 CG33254 http://flybase.net/reports/FBgn0040887.html "FBgn0053254, FBgn0063659" protein_coding_gene "CG7418, BcDNA:RH26422" 16-Dec-15 2015_12 FBgn0058338 CG40338 http://flybase.net/reports/FBgn0058338.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034447 CG7744 http://flybase.net/reports/FBgn0034447.html protein_coding_gene "IPR018617=Ima1, N-terminal domain" CG7744 16-Dec-15 2015_12 ENSMUSG00000044700(Tmem201) ENSG00000188807(TMEM201) viable FBgn0023092 dh62 dh62 http://flybase.net/reports/FBgn0023092.html gene 16-Dec-15 2015_12 FBgn0011488 l(3)neo58b lethal (3) neo58b http://flybase.net/reports/FBgn0011488.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011931 tRNA:N5:42Aa transfer RNA:asn5:42Aa http://flybase.net/reports/FBgn0011931.html "FBgn0003759, FBgn0050309, FBgn0050510, FBgn0060128" tRNA_gene "0033442=AAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30510, tRNA:asn5:42Aa, CR30309, AE002769.trna13-AsnGTT, tRNA:N:GTT:AE002769-f, asn-tRNA, chr2R.trna5-AsnGTT" CR30510 16-Dec-15 2015_12 FBgn0005039 e(tu-K) enhancer of tumor K http://flybase.net/reports/FBgn0005039.html gene 16-Dec-15 2015_12 FBgn0039682 Obp99c Odorant-binding protein 99c http://flybase.net/reports/FBgn0039682.html protein_coding_gene 0005549=odorant binding "0007606=sensory perception of chemical stimulus, 0009620=response to fungus" 0005576=extracellular region "Obp 99c, CG7584, DmelObp99c, Obp99b, 99c" IPR006170=Pheromone/general odorant binding protein CG7584 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0051172 CG31172 http://flybase.net/reports/FBgn0051172.html protein_coding_gene 16-Dec-15 2015_12 FBgn0070001 BG01575 BG01575 http://flybase.net/reports/FBgn0070001.html gene 16-Dec-15 2015_12 stress response defective FBgn0054040 CG34040 http://flybase.net/reports/FBgn0054040.html FBgn0082891 protein_coding_gene "unnamed, BP1015" IPR008472=Domain of unknown function DUF753 CG34040 16-Dec-15 2015_12 FBgn0000235 btm breaks at metaphase http://flybase.net/reports/FBgn0000235.html gene "breaks at metaphase, bam" 16-Dec-15 2015_12 mitotic cell cycle defective FBgn0266350 CR44999 http://flybase.net/reports/FBgn0266350.html non_protein_coding_gene CR44999 16-Dec-15 2015_12 FBgn0035690 CG10274 http://flybase.net/reports/FBgn0035690.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG10274 16-Dec-15 2015_12 WBGene00004773(sem-4) viable DRSC09716 K 0.492532681 0.30541536 0.460820667 -0.604529626 -0.377891507 2.032010074 FBgn0000699 fltE flight defective E http://flybase.net/reports/FBgn0000699.html gene 16-Dec-15 2015_12 flight defective FBgn0070042 3R-31-22 3R-31-22 http://flybase.net/reports/FBgn0070042.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0086657 IKKëµ I-kappaB kinase ëµ http://flybase.net/reports/FBgn0086657.html "FBgn0025164, FBgn0028633, FBgn0043071" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005515=protein binding, 0008384=IkappaB kinase activity, 0005524=ATP binding" "0016322=neuron remodeling, 0032456=endocytic recycling, 0001578=microtubule bundle formation, 0008407=chaeta morphogenesis, 0007314=oocyte anterior/posterior axis specification, 0018105=peptidyl-serine phosphorylation, 0045035=sensory organ precursor cell division, 0035160=maintenance of epithelial integrity, open tracheal system, 0006468=protein phosphorylation, 0061572=actin filament bundle organization, 0043280=positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, 0006952=defense response, 0051493=regulation of cytoskeleton organization, 0000902=cell morphogenesis, 0007165=signal transduction, 0007015=actin filament organization, 0036290=protein trans-autophosphorylation, 0008219=cell death" "0051286=cell tip, 0005737=cytoplasm, 0008385=IkappaB kinase complex" "Dik2, IK2, IKK-related kinase, CG2615, 38D.31, IKK, ik2, DmIKKepsilon/dIK2, lethal (2) 38Ea, DmIKKepsilon, IKKepsilon, apoptoxin 7, Ik2/DmIKK, dIKK, APTX7, dik2, l(2)38Ea, DIK2, Dmik2, Ik2, IkappaB kinase-like 2" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR029071=Ubiquitin-related domain, IPR017441=Protein kinase, ATP binding site" CG2615 16-Dec-15 2015_12 "ENSDARG00000070606(ikbke),ENSDARG00000070591,ENSDARG00000063708(tbk1)" "WBGene00012726(Y39G8B.5),WBGene00011299(ikke-1)" ENSXETG00000007322(TBK1) "ENSMUSG00000020115(Tbk1),ENSMUSG00000042349(Ikbke)" "ENSG00000183735(TBK1),ENSG00000143466(IKBKE)" FBgn0085458 CG34429 http://flybase.net/reports/FBgn0085458.html "FBan0014116, FBgn0036344" protein_coding_gene CG14116 IPR006631=Protein of unknown function DM4/12 CG34429 16-Dec-15 2015_12 FBgn0028562 sut2 sugar transporter 2 http://flybase.net/reports/FBgn0028562.html FBgn0033255 protein_coding_gene "0005355=glucose transmembrane transporter activity, 0005351=sugar:proton symporter activity" 0055085=transmembrane transport 0016021=integral component of membrane CG17975 "IPR005828=Major facilitator, sugar transporter-like, IPR003663=Sugar/inositol transporter, IPR020846=Major facilitator superfamily domain" CG17975 16-Dec-15 2015_12 YNL318C(HXT14) viable FBgn0266986 CR45437 http://flybase.net/reports/FBgn0266986.html non_protein_coding_gene CR45437 16-Dec-15 2015_12 FBgn0052109 CG32109 http://flybase.net/reports/FBgn0052109.html FBgn0036304 protein_coding_gene CG10982 CG32109 16-Dec-15 2015_12 ENSMUSG00000037257(Aagab) ENSG00000103591(AAGAB) FBgn0036031 CG6761 http://flybase.net/reports/FBgn0036031.html protein_coding_gene IPR021777=Protein of unknown function DUF3342 CG6761 16-Dec-15 2015_12 ENSXETG00000002217(KIAA1841) ENSMUSG00000042208(0610010F05Rik) ENSG00000162929(KIAA1841) FBgn0065958 l(2)SH0052 lethal (2) SH0052 http://flybase.net/reports/FBgn0065958.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262374 mir-2b-1 mir-2b-1 stem loop http://flybase.net/reports/FBgn0262374.html "FBgn0046824, FBgn0262186" miRNA_gene "0060548=negative regulation of cell death, 0045947=negative regulation of translational initiation, 0046716=muscle cell cellular homeostasis" "CR32990, miR2, miR-2b-1, miR2b, CR42893, dme-miR-2b-3p, dme-miR-2b, mir-2b, miR-2b1, dme-mir-2b-1, mir-2b-1, miR-2b, 2b-1/2, miR-2" CR42893 16-Dec-15 2015_12 embryonic stage -- adult stage "visible,lethal" wing vein FBgn0004619 GluRIA Glutamate receptor IA http://flybase.net/reports/FBgn0004619.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity" 0006812=cation transport "0016021=integral component of membrane, 0016020=membrane, 0008328=ionotropic glutamate receptor complex" "unnamed, glutamate receptor, DGluR-I, GluR1, CG8442, kainate receptor, dGluRI, dglur-IA, DGluR-IA, Glutamate receptor I, GluRI, glutamate receptor kainate-selective subunit, Dro GluRIA, GluRIA, DmelGlu-R1, Glu-R1, DGluRI, Glu-RI" "IPR028082=Periplasmic binding protein-like I, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor, IPR001828=Receptor, ligand binding region" CG8442 16-Dec-15 2015_12 "ENSDARG00000052765(gria2b),ENSDARG00000070173(gria2a),ENSDARG00000059368(gria4b),ENSDARG00000037498(gria3b),ENSDARG00000021352(gria1a),ENSDARG00000032737(gria3a),ENSDARG00000032714(gria1b),ENSDARG00000021104" "WBGene00001612(glr-1),WBGene00001613(glr-2)" "ENSXETG00000001922(GRIA1),ENSXETG00000019504(GRIA3)" "ENSMUSG00000033981(Gria2),ENSMUSG00000025892(Gria4),ENSMUSG00000001986(Gria3),ENSMUSG00000020524(Gria1)" "ENSG00000120251(GRIA2),ENSG00000152578(GRIA4),ENSG00000125675(GRIA3),ENSG00000155511(GRIA1)" embryonic stage | late " subesophageal ganglion

, ventral nerve cord

, supraesophageal ganglion

" "viable,fertile" FBgn0034377 CG15071 http://flybase.net/reports/FBgn0034377.html protein_coding_gene CG15071 16-Dec-15 2015_12 viable FBgn0020625 P-1 proteoglycan-1 http://flybase.net/reports/FBgn0020625.html gene "DROP-1, Drosophila proteoglycan, DP-1" 16-Dec-15 2015_12 FBgn0004662 mbd mushroom body deranged http://flybase.net/reports/FBgn0004662.html "FBgn0002686, FBgn0002695" gene "0008355=olfactory learning, 0016319=mushroom body development" "mushroom bodies deranged, MBD, mdb, mushroom body-deranged" 16-Dec-15 2015_12 behavior defective "Kenyon cell,ellipsoid body,nodulus,adult central complex,neuropil,adult mushroom body,calyx of adult mushroom body,lobe system of adult mushroom body" FBgn0030908 CG15057 http://flybase.net/reports/FBgn0030908.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0261973 snoRNA:Or-CD9a http://flybase.net/reports/FBgn0261973.html "FBgn0082918, FBgn0083060" snoRNA_gene 0005654=nucleoplasm "snmRNA:60Ca, DmOr_cd9a snoRNA, CR34566, CR34156, Dmsnm60a, snoRNA:Or-cd9a, orphan CD9a, DmOrC/D_9a, snm60, small non-messenger RNA 60Ca, CR42804, DmOr_cd9a, Snm60a" CR42804 16-Dec-15 2015_12 FBgn0002956 nofL no object fixation L http://flybase.net/reports/FBgn0002956.html gene 16-Dec-15 2015_12 "eye color defective,visual behavior defective" "optic lobe,rhabdomere | adult stage,pigment cell" FBgn0264352 CR43808 http://flybase.net/reports/FBgn0264352.html non_protein_coding_gene lincRNA.55 CR43808 16-Dec-15 2015_12 FBgn0011590 fms(445B) fms(445B) http://flybase.net/reports/FBgn0011590.html gene 16-Dec-15 2015_12 FBgn0266563 EP985 http://flybase.net/reports/FBgn0266563.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0069204 l(2)46Dj lethal (2) 46Dj http://flybase.net/reports/FBgn0069204.html gene Complementation group CC 16-Dec-15 2015_12 "lethal,visible,dominant" wing FBgn0053365 5SrRNA:CR33365 5SrRNA:CR33365 http://flybase.net/reports/FBgn0053365.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33365 CR33365 16-Dec-15 2015_12 FBgn0036361 CG10154 http://flybase.net/reports/FBgn0036361.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG10154 16-Dec-15 2015_12 viable FBgn0003510 Sry-ë± Serendipity ë± http://flybase.net/reports/FBgn0003510.html protein_coding_gene 0003779=actin binding "0007015=actin filament organization, 0007010=cytoskeleton organization, 0000915=actomyosin contractile ring assembly, 0007349=cellularization" "0005737=cytoplasm, 0005829=cytosol, 0005886=plasma membrane, 0016020=membrane, 0032154=cleavage furrow, 0031941=filamentous actin" "ser, Sryalpha, sryalpha, sry-alpha, Sry alpha, Serendipity-alpha, sry alpha, Sry-alpha, serendipity-alpha, CG17957, sry, serendipity alpha, Serendipity alpha, srya, sry-a, serendipity" IPR008837=Serendipity locus alpha CG17957 16-Dec-15 2015_12 " embryonic stage | embryonic cycle 11 , embryonic stage | embryonic cycle 14 , embryonic stage | blastoderm , embryonic stage | stage 4-6 , embryonic stage | stage 4-8 , embryonic stage | early " " organism | 0-20% egg length

, organism | 40-80% egg length

" " embryonic stage | stage 5-7 , embryonic stage | early , embryonic stage | embryonic cycle 14 " "wild-type,viable" FBgn0031473 CG3104 http://flybase.net/reports/FBgn0031473.html protein_coding_gene "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG3104 16-Dec-15 2015_12 ENSDARG00000057159(ankrd29) YGR232W(NAS6) WBGene00013835(mlt-4) "ENSXETG00000025138(),ENSXETG00000009503(ANKRD52),ENSXETG00000010515(),ENSXETG00000011663(ANKK1),ENSXETG00000008989(ankrd28)" ENSMUSG00000057766(Ankrd29) ENSG00000154065(ANKRD29) "viable,visible" trichogen cell FBgn0263085 CR43353 http://flybase.net/reports/FBgn0263085.html non_protein_coding_gene "lincRNA.182, CG43353" CR43353 16-Dec-15 2015_12 FBgn0033904 CG18327 http://flybase.net/reports/FBgn0033904.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG18327 16-Dec-15 2015_12 ENSDARG00000014802(si:ch211-268m12.5) YKL120W(OAC1) "ENSMUSG00000018740(Slc25a35),ENSMUSG00000040740(Slc25a34)" ENSG00000162461(SLC25A34) "viable,fertile" FBgn0022710 Ac13E Adenylyl cyclase 35C http://flybase.net/reports/FBgn0022710.html protein_coding_gene 0004016=adenylate cyclase activity "0006171=cAMP biosynthetic process, 0035556=intracellular signal transduction" 0016021=integral component of membrane "AC 13E, Ac35C, Adenyly cyclase 35C, DAC9, adenylyl cyclase, CG9210, AC13E" "IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG9210 16-Dec-15 2015_12 WBGene00000068(acy-1) ENSXETG00000017315(ADCY9) ENSMUSG00000005580(Adcy9) ENSG00000162104(ADCY9) " adult stage , larval stage , embryonic stage -- adult stage " "viable,visible" trichogen cell FBgn0024302 Sbp3 Su(H)-binding protein 3 http://flybase.net/reports/FBgn0024302.html gene 0008134=transcription factor binding "sbp3, SBP3" 16-Dec-15 2015_12 FBgn0263270 CG43396 http://flybase.net/reports/FBgn0263270.html protein_coding_gene CG43396 16-Dec-15 2015_12 FBgn0264444 CR43862 http://flybase.net/reports/FBgn0264444.html non_protein_coding_gene CR43862 16-Dec-15 2015_12 FBgn0003089 pip pipe http://flybase.net/reports/FBgn0003089.html protein_coding_gene "0005515=protein binding, 0008146=sulfotransferase activity, 0034483=heparan sulfate sulfotransferase activity, 0034481=chondroitin sulfotransferase activity, 0004394=heparan sulfate 2-O-sulfotransferase activity" "0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway, 0040014=regulation of multicellular organism growth, 0016485=protein processing, 0007313=maternal specification of dorsal/ventral axis, oocyte, soma encoded, 0048477=oogenesis, 0009880=embryonic pattern specification" "0016021=integral component of membrane, 0005794=Golgi apparatus, 0005694=chromosome, 0005634=nucleus" "l(3)76BDp, pipe-ST2, Pipe, pipe, CG9614" "IPR005331=Sulfotransferase, IPR007734=Heparan sulphate 2-O-sulfotransferase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9614 16-Dec-15 2015_12 " embryonic stage | stage >=12 , adult stage && oogenesis stage | stage S9-10 , embryonic stage , oogenesis stage , embryonic stage | stage >=14 " " embryonic/larval pharynx | anterior

, follicle cell | ventral

, gonad | presumptive

, embryonic/larval salivary gland

" "viable,fertile,partially lethal - majority die,developmental rate defective,small body" "embryonic/first instar larval cuticle,embryonic epidermis,maternal effect,somatic clone,denticle field,embryo,ventral,presumptive embryonic salivary gland" FBgn0001449 l(1)7Dc lethal (1) 7Dc http://flybase.net/reports/FBgn0001449.html gene l(1)VE470 16-Dec-15 2015_12 FBgn0038088 CG10126 http://flybase.net/reports/FBgn0038088.html protein_coding_gene 0005509=calcium ion binding 0022008=neurogenesis CT28495 "IPR002048=EF-hand domain, IPR029633=Calcyphosin-like protein, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG10126 16-Dec-15 2015_12 "ENSDARG00000003414(zgc:110369),ENSDARG00000039341" "ENSXETG00000018707(CAPSL),ENSXETG00000021881()" ENSMUSG00000039676(Capsl) ENSG00000152611(CAPSL) "lethal,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell" FBgn0261720 Su(Gl)160 http://flybase.net/reports/FBgn0261720.html gene 16-Dec-15 2015_12 FBgn0011100 l(1)Q61 lethal (1) Q61 http://flybase.net/reports/FBgn0011100.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0261548 CG42666 http://flybase.net/reports/FBgn0261548.html "FBgn0024988, FBgn0029591, FBgn0023543, FBgn0029592" protein_coding_gene "0004527=exonuclease activity, 0003676=nucleic acid binding" "CG14801, CG14799, EG:131F2.2, CG17968, CG14800, EG:137E7.1" "IPR013520=Exonuclease, RNase T/DNA polymerase III, IPR012337=Ribonuclease H-like domain" CG42666 16-Dec-15 2015_12 """DRSC17957, DRSC18490"" " IEK FBgn0266807 CR45269 http://flybase.net/reports/FBgn0266807.html non_protein_coding_gene CR45269 16-Dec-15 2015_12 FBgn0034919 CG5569 http://flybase.net/reports/FBgn0034919.html FBgn0062866 protein_coding_gene 0022008=neurogenesis BcDNA:SD18780 IPR007523=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 CG5569 16-Dec-15 2015_12 ENSXETG00000024755(Q6DFN1_XENTR) ENSMUSG00000070283(Ndufaf3) ENSG00000178057(NDUFAF3) "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0259400 EP-J17b http://flybase.net/reports/FBgn0259400.html gene 16-Dec-15 2015_12 visible wing FBgn0016018 l(3)73CFa lethal (3) 73CFa http://flybase.net/reports/FBgn0016018.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011461 l(3)neo27 lethal (3) neo27 http://flybase.net/reports/FBgn0011461.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016975 stnB stoned B http://flybase.net/reports/FBgn0016975.html "FBan0012473, FBgn0003533, FBgn0058306, FBgn0063778" protein_coding_gene 0005515=protein binding "0016183=synaptic vesicle coating, 0006901=vesicle coating, 0048489=synaptic vesicle transport, 0007268=synaptic transmission, 1900242=regulation of synaptic vesicle endocytosis, 0007269=neurotransmitter secretion, 0048488=synaptic vesicle endocytosis" "0005886=plasma membrane, 0016021=integral component of membrane, 0030139=endocytic vesicle, 0008021=synaptic vesicle, 0030135=coated vesicle" "STNB, StnB, ORF2, CG12473/CG12500, Stoned B, stn, Stoned, stn-B, stonedB, CG12473, stoned, CG40306, stoned-B, StonedB" "IPR012320=Stonin homology, IPR017110=Stonin, IPR028565=Mu homology domain" CG12473 16-Dec-15 2015_12 WBGene00006777(unc-41) "ENSMUSG00000020961(Ston2),ENSMUSG00000033855" "ENSG00000140022(STON2),ENSG00000068781(STON1-GTF2A1L)" adult stage adult stage " adult head

, adult abdomen

, adult thorax

" "uncoordinated,recessive,neurophysiology defective,lethal,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during pupal stage,short lived,neuroanatomy defective,viable" "axon terminus,synaptic vesicle,multivesicular body,embryonic/larval neuromuscular junction,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage,synaptic vesicle | third instar larval stage, with P{UAS-stnB.M}vl" FBgn0031662 CG3792 http://flybase.net/reports/FBgn0031662.html FBgn0027670 protein_coding_gene 0006486=protein glycosylation 0016021=integral component of membrane anon-EST:Posey8 "IPR016817=Mannose-P-dolichol utilization defect 1 protein, IPR006603=PQ-loop repeat" CG3792 16-Dec-15 2015_12 ENSDARG00000040265(mpdu1b) WBGene00018181(F38E1.9) ENSMUSG00000018761(Mpdu1) viable FBgn0266181 CRG CASK regulatory gene http://flybase.net/reports/FBgn0266181.html non_protein_coding_gene 0045944=positive regulation of transcription from RNA polymerase II promoter CR44887 CR44887 16-Dec-15 2015_12 "viable,fertile,gravitaxis defective,locomotor behavior defective" FBgn0005397 Dia1 Diaphorase 1 http://flybase.net/reports/FBgn0005397.html gene 0004148=dihydrolipoyl dehydrogenase activity DIA-1 16-Dec-15 2015_12 FBgn0065668 l(2)SH0692 lethal (2) SH0692 http://flybase.net/reports/FBgn0065668.html gene l(2)SH2 0692 16-Dec-15 2015_12 "lethal,recessive" FBgn0259422 C441 http://flybase.net/reports/FBgn0259422.html gene 16-Dec-15 2015_12 visible wing hair FBgn0085623 CG41337 http://flybase.net/reports/FBgn0085623.html FBan0041337 protein_coding_gene 16-Dec-15 2015_12 FBgn0067345 l(3)B197 lethal (3) B197 http://flybase.net/reports/FBgn0067345.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024714 anon-57Cm anon-57Cm http://flybase.net/reports/FBgn0024714.html gene unnamed 16-Dec-15 2015_12 FBgn0260782 5-103 http://flybase.net/reports/FBgn0260782.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0002778 mnd minidiscs http://flybase.net/reports/FBgn0002778.html "FBgn0002474, FBgn0004717" protein_coding_gene 0015171=amino acid transmembrane transporter activity "0003333=amino acid transmembrane transport, 0006865=amino acid transport, 0060356=leucine import" 0016020=membrane "minidisks, l(3)SG29, l(3)ds-5, Minidiscs, l(3)ds5, SG29, CG3297, md, l(3)B5, l(3)o52" IPR002293=Amino acid/polyamine transporter I CG3297 16-Dec-15 2015_12 "ENSDARG00000055226(slc7a7),ENSDARG00000054423(slc7a6),ENSDARG00000020278(LOC566469)" "YGR055W(MUP1),YHL036W(MUP3)" WBGene00000003(aat-2) ENSG00000103257(SLC7A5) " embryonic stage , larval stage | first instar -- larval stage | second instar , larval stage | third instar , adult stage " " organism

, embryonic/larval fat body

" "viable,fertile,lethal,heat sensitive,lethal - all die before end of larval stage,recessive,some die during larval stage,cold sensitive,wild-type" "pupa,embryonic/larval brain,stage A1 adult,embryonic/larval fat body,imaginal disc,third instar larva,adult,embryo,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc,larva,second instar larva" DRSC11370 I 0.208871109 -1.672097059 -0.602394188 -0.65190198 -0.390442967 -0.451043904 FBgn0035589 CHMP2B Charged multivesicular body protein 2b http://flybase.net/reports/FBgn0035589.html protein_coding_gene "0007034=vacuolar transport, 0016197=endosomal transport" 0000815=ESCRT III complex "cg4618, CG4618" IPR005024=Snf7 family CG4618 16-Dec-15 2015_12 "ENSDARG00000002190(chmp2bl),ENSDARG00000068728,ENSDARG00000068683(LOC569532)" WBGene00007216(C01A2.4) ENSXETG00000007638(CHM2B_XENTR) ENSMUSG00000004843(Chmp2b) ENSG00000083937(CHMP2B) FBgn0267820 CR46145 http://flybase.net/reports/FBgn0267820.html non_protein_coding_gene CR46145 16-Dec-15 2015_12 FBgn0026645 l(2)k02503 lethal (2) k02503 http://flybase.net/reports/FBgn0026645.html gene 16-Dec-15 2015_12 FBgn0263376 CR43428 http://flybase.net/reports/FBgn0263376.html non_protein_coding_gene CG12865 CR43428 16-Dec-15 2015_12 FBgn0004926 eIF-2ë_ Eukaryotic initiation factor 2ë_ http://flybase.net/reports/FBgn0004926.html FBgn0024970 protein_coding_gene "0000049=tRNA binding, 0003743=translation initiation factor activity, 0005525=GTP binding" "0007052=mitotic spindle organization, 0006413=translational initiation, 0034976=response to endoplasmic reticulum stress, 0016199=axon midline choice point recognition, 0000022=mitotic spindle elongation, 0001677=formation of translation initiation ternary complex" "0005875=microtubule associated complex, 0005829=cytosol, 0005850=eukaryotic translation initiation factor 2 complex" "eIF-2, elF2beta, Eif2beta, eIF-2beta, CG4153, D-eIF2beta, IF2B, eIF2beta" "IPR002735=Translation initiation factor IF2/IF5, IPR016189=Translation initiation factor IF2/IF5, N-terminal, IPR016190=Translation initiation factor IF2/IF5, zinc-binding" CG4153 16-Dec-15 2015_12 ENSDARG00000053047(eif2s2) YPL237W(SUI3) WBGene00010560(iftb-1) ENSXETG00000019507(eif2s2) "ENSMUSG00000074656(Eif2s2),ENSMUSG00000052825(Gm9892)" "ENSG00000125977(EIF2S2),ENSG00000128692" embryonic stage -- adult stage "lethal,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "axon & pCC neuron,axon & pCC neuronED4486)" DRSC11341 EK -1.104901511 1.215548193 -1.221397396 -2.42423921 2.310376135 0.36974402 FBgn0259226 CG42326 http://flybase.net/reports/FBgn0259226.html "FBgn0033306, FBgn0033305" protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG14747, CG14748" IPR003609=PAN/Apple domain CG42326 16-Dec-15 2015_12 FBgn0060659 l(3)SzB89Bb lethal (3) SzB89Bb http://flybase.net/reports/FBgn0060659.html gene "l(3)S082609b, 0826/09" 16-Dec-15 2015_12 lethal FBgn0265172 T:TM-Sema-1a Transmembrane domain of Sema-1a http://flybase.net/reports/FBgn0265172.html engineered_tag 16-Dec-15 2015_12 FBgn0036893 CG9376 http://flybase.net/reports/FBgn0036893.html protein_coding_gene 0006506=GPI anchor biosynthetic process "0016021=integral component of membrane, 0005789=endoplasmic reticulum membrane" IPR009580=GPI biosynthesis protein Pig-F CG9376 16-Dec-15 2015_12 ENSDARG00000032780(pigf) ENSXETG00000026168(PIGF) viable FBgn0262847 CR43211 http://flybase.net/reports/FBgn0262847.html pseudogene_attribute CR43211 16-Dec-15 2015_12 FBgn0067637 106y 106y http://flybase.net/reports/FBgn0067637.html gene 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0022363 Pt-9 Larval protein-9 http://flybase.net/reports/FBgn0022363.html gene PT-9 16-Dec-15 2015_12 FBgn0019689 l(3)92Eb lethal (3) 92Eb http://flybase.net/reports/FBgn0019689.html gene HSH11 16-Dec-15 2015_12 "lethal,partially,recessive" FBgn0264494 CG17646 http://flybase.net/reports/FBgn0264494.html "FBgn0065927, FBgn0031362, FBgn0031363, FBgn0043837" protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006641=triglyceride metabolic process 0043190=ATP-binding cassette (ABC) transporter complex "l(2)SH0142, lethal (2) SH0142, BEST:GH05015, CG17647, ABCG1, ATP-binding cassette transporter G1, l(2)SH2 0142" "IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain" CG17646 16-Dec-15 2015_12 FBgn0033798 CG15870 http://flybase.net/reports/FBgn0033798.html protein_coding_gene CG15870 16-Dec-15 2015_12 FBgn0034391 CG15080 http://flybase.net/reports/FBgn0034391.html protein_coding_gene CG15080 16-Dec-15 2015_12 FBgn0086686 l(3)L1231 lethal (3) L1231 http://flybase.net/reports/FBgn0086686.html "FBgn0026578, FBgn0038249, FBgn0024535" protein_coding_gene "0002121=inter-male aggressive behavior, 0042332=gravitaxis" "CG7832, LD14744, BEST:LD14744" IPR025927=Potential DNA-binding domain CG7832 16-Dec-15 2015_12 ENSG00000114933(INO80D) FBgn0061112 l(3)SzB90Ce lethal (3) SzB90Ce http://flybase.net/reports/FBgn0061112.html gene "l(3)S006517b, 0065/17" 16-Dec-15 2015_12 "lethal,recessive" FBgn0060798 l(3)S057706b lethal (3) S057706b http://flybase.net/reports/FBgn0060798.html gene 0577/06 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0027144 l(3)71DEc lethal (3) 71DEc http://flybase.net/reports/FBgn0027144.html gene 1(3)71DEc 16-Dec-15 2015_12 "lethal,recessive" FBgn0084039 CG41479 http://flybase.net/reports/FBgn0084039.html FBan0041479 protein_coding_gene 16-Dec-15 2015_12 FBgn0067675 nansen nansen http://flybase.net/reports/FBgn0067675.html gene "0045450=bicoid mRNA localization, 0045451=pole plasm oskar mRNA localization" nan 16-Dec-15 2015_12 "oocyte,germline clone,oocyte nucleus" FBgn0066350 l(3)99DEe lethal (3) 99DEe http://flybase.net/reports/FBgn0066350.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031749 CG14000 http://flybase.net/reports/FBgn0031749.html protein_coding_gene CG14000 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0011636 l(2)T57h9 lethal (2) T57h9 http://flybase.net/reports/FBgn0011636.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0003876 tu(2)48 tumor(2)48 http://flybase.net/reports/FBgn0003876.html gene tu-48a 16-Dec-15 2015_12 "melanotic mass phenotype,viable,fertile" FBgn0001097 Gull Gulloid http://flybase.net/reports/FBgn0001097.html gene Gd 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" wing FBgn0005713 l(1)TK116 lethal (1) TK116 http://flybase.net/reports/FBgn0005713.html gene l116 16-Dec-15 2015_12 "lethal,recessive" FBgn0036913 Usp32 Ubiquitin specific protease 32 http://flybase.net/reports/FBgn0036913.html protein_coding_gene "0005509=calcium ion binding, 0004843=ubiquitin-specific protease activity" "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" "USP15, CG8334, Q9VW49" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR018200=Ubiquitin specific protease, conserved site, IPR006615=Peptidase C19, ubiquitin-specific peptidase, DUSP domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR002048=EF-hand domain, IPR028889=Ubiquitin specific protease domain" CG8334 16-Dec-15 2015_12 ENSDARG00000061895(LOC557981) YJL197W(UBP12) WBGene00000874(cyk-3) ENSXETG00000013503() ENSMUSG00000000804(Usp32) "ENSG00000170832(USP32),ENSG00000129204(USP6)" viable FBgn0266240 CR44935 http://flybase.net/reports/FBgn0266240.html non_protein_coding_gene lincRNA.716 CR44935 16-Dec-15 2015_12 FBgn0002635 mab malformed abdomen http://flybase.net/reports/FBgn0002635.html gene "Ecmab, Ebmab" 16-Dec-15 2015_12 "visible,recessive,lethal,heat sensitive" "abdomen,heat sensitive,cuticle" FBgn0013321 Pcp8 Pupal-cuticle-protein-8kD http://flybase.net/reports/FBgn0013321.html gene 16-Dec-15 2015_12 FBgn0040945 CG12639 http://flybase.net/reports/FBgn0040945.html protein_coding_gene 16-Dec-15 2015_12 FBgn0016843 l(1)N17 lethal (1) N17 http://flybase.net/reports/FBgn0016843.html gene N17 16-Dec-15 2015_12 "lethal,recessive" FBgn0027122 l(?)5A lethal (?) 5A http://flybase.net/reports/FBgn0027122.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032249 CG5337 http://flybase.net/reports/FBgn0032249.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity IPR000195=Rab-GTPase-TBC domain CG5337 16-Dec-15 2015_12 ENSDARG00000036994 YDL234C(GYP7) WBGene00018639(tbc-16) ENSXETG00000012824(TBC1D16) ENSMUSG00000039976(Tbc1d16) ENSG00000167291(TBC1D16) viable FBgn0264383 CR43835 http://flybase.net/reports/FBgn0264383.html non_protein_coding_gene lincRNA.961 CR43835 16-Dec-15 2015_12 FBgn0083095 cbe celibe http://flybase.net/reports/FBgn0083095.html gene "0007111=meiosis II cytokinesis, 0051225=spindle assembly, 0007110=meiosis I cytokinesis, 0000915=actomyosin contractile ring assembly" 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,cytokinesis defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic cell cycle | male,contractile ring & meiotic cell cycle | male" FBgn0016700 Rab1 Rab1 http://flybase.net/reports/FBgn0016700.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0016192=vesicle-mediated transport, 0006888=ER to Golgi vesicle-mediated transport, 0032482=Rab protein signal transduction, 0007015=actin filament organization, 0030334=regulation of cell migration, 0007155=cell adhesion, 0050775=positive regulation of dendrite morphogenesis, 0033500=carbohydrate homeostasis, 0008360=regulation of cell shape, 0032024=positive regulation of insulin secretion, 0008089=anterograde axon cargo transport, 0009306=protein secretion" "0005737=cytoplasm, 0005811=lipid particle, 0031982=vesicle, 0043025=neuronal cell body" "Rab-protein 1, dRab1, Rab1a, dar6, Dm Rab1, dendritic arbor reduction 6, DRAB1, AAF55873, rab1, DRab1, CG3320, O18332, drab1, DmRab1, RAB1a" "IPR003579=Small GTPase superfamily, Rab type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG3320 16-Dec-15 2015_12 "ENSDARG00000029663(rab1a),ENSDARG00000052263,ENSDARG00000058044(zgc:56049),ENSDARG00000056479(zgc:86773)" YFL038C(YPT1) WBGene00004266(rab-1) ENSXETG00000014011(rab1a) "ENSMUSG00000020149(Rab1),ENSMUSG00000024870(Rab1b)" "ENSG00000174903(RAB1B),ENSG00000138069(RAB1A)" "lethal,neuroanatomy defective,female sterile,germline clone,recessive,cell lethal,body size defective,developmental rate defective" "dendrite & dendritic arborising neuron,Golgi apparatus & photoreceptor cellhs.PB,rough endoplasmic reticulum & photoreceptor cellhs.PB,microvillus & photoreceptor cellhs.PB,larval dorsomedial neurosecretory cell,dendriteIlp2.PW" DRSC29851 K -0.349198566 0.527084484 0.697887987 -1.087054899 -1.295831944 -1.524727707 FBgn0004175 Mst84Dd Male-specific RNA 84Dd http://flybase.net/reports/FBgn0004175.html protein_coding_gene "0007283=spermatogenesis, 0007288=sperm axoneme assembly" "mst(3)gl-4, Mst84, CG17935, Mst87D, Mst, Mst ORF, Mstprox" IPR005634=Male specific sperm protein CG17935 16-Dec-15 2015_12 viable FBgn0014019 Rh5 Rhodopsin 5 http://flybase.net/reports/FBgn0014019.html protein_coding_gene 0008020=G-protein coupled photoreceptor activity "0009588=UV-A, blue light phototransduction, 0007605=sensory perception of sound, 0007186=G-protein coupled receptor signaling pathway, 0007602=phototransduction, 0043153=entrainment of circadian clock by photoperiod, 0016038=absorption of visible light, 0009416=response to light stimulus, 0007601=visual perception" "0016028=rhabdomere, 0016021=integral component of membrane" "rh5, rhodopsin 5, Dm Rh5, DMELRH5, CG5279, Rh, rhodopsin, rhodopsin-5, Rhodopsin5, Rhodopsin, RH5" "IPR027430=Visual pigments (opsins) retinal binding site, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000856=Opsin RH3/RH4" CG5279 16-Dec-15 2015_12 adult stage " adult head

, photoreceptor cell R8

" adult stage photoreceptor cell R8

"phototaxis defective,auditory perception defective,neurophysiology defective,visual behavior defective" eye photoreceptor cell FBgn0028410 Pk34A Pk34A http://flybase.net/reports/FBgn0028410.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" 0006468=protein phosphorylation "CG5182, GSK3a" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG5182 16-Dec-15 2015_12 viable FBgn0051960 CG31960 http://flybase.net/reports/FBgn0051960.html FBgn0031570 protein_coding_gene 0005509=calcium ion binding CG10022 "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG31960 16-Dec-15 2015_12 FBgn0037525 CG17816 http://flybase.net/reports/FBgn0037525.html protein_coding_gene 0005634=nucleus IPR029136=Nuclear protein MDM1 CG17816 16-Dec-15 2015_12 DRSC15277 I -0.312071859 -1.533154081 0.267109373 -0.640753046 0.106762644 0.008576105 FBgn0262857 CG43221 http://flybase.net/reports/FBgn0262857.html protein_coding_gene DMG8-chr2L.31.003 CG43221 16-Dec-15 2015_12 FBgn0086677 jeb jelly belly http://flybase.net/reports/FBgn0086677.html "FBgn0033681, FBgn0065792, FBgn0022161, FBgn0040761, FBgn0050040" protein_coding_gene 0030297=transmembrane receptor protein tyrosine kinase activator activity "1900074=negative regulation of neuromuscular synaptic transmission, 0007411=axon guidance, 0007522=visceral muscle development, 0051124=synaptic growth at neuromuscular junction, 0007509=mesoderm migration involved in gastrulation, 0042694=muscle cell fate specification, 0043410=positive regulation of MAPK cascade, 0007435=salivary gland morphogenesis, 0042051=compound eye photoreceptor development" "0043195=terminal bouton, 0005576=extracellular region, 0061176=type Ib terminal bouton, 0061177=type Is terminal bouton, 0005615=extracellular space, 0008021=synaptic vesicle" "jellybelly, l(2)SH0422, CG30040, CG13180, jelly-belly, Jelly belly, l(2)k05644, jelly belly, Jelly Belly, CG13182, lethal (2) SH0422, Jeb" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG30040 16-Dec-15 2015_12 FBgn0011239 ms(2)35Ci male sterile (2) 35Ci http://flybase.net/reports/FBgn0011239.html "FBgn0045996, FBgn0051733, FBgn0063291" protein_coding_gene 0048515=spermatid differentiation "ms(2)35Ci, CG31733, ms(2)02316, BcDNA:AT28918, male sterile(2)46AB, NEST:bs29a09, ms(2)46AB" CG31733 16-Dec-15 2015_12 "male sterile,recessive,male fertile,partially lethal - majority die,viable" FBgn0032685 CG10211 http://flybase.net/reports/FBgn0032685.html protein_coding_gene "0020037=heme binding, 0004601=peroxidase activity" "0055114=oxidation-reduction process, 0006979=response to oxidative stress" "IPR010255=Haem peroxidase, IPR019791=Haem peroxidase, animal" CG10211 16-Dec-15 2015_12 "WBGene00011530(T06D8.10),WBGene00016700(C46A5.4)" "ENSXETG00000007787(),ENSXETG00000019727()" "ENSG00000005381(MPO),ENSG00000121053(EPX),ENSG00000167419(LPO)" lethal DRSC02027 IE -0.234617269 -1.609864547 1.011576503 1.900762961 -0.502999389 -1.036015335 FBgn0264079 T:Myr-Src64B Myristoylation sequence of Src64B http://flybase.net/reports/FBgn0264079.html "FBgn0024719, FBgn0262865" engineered_tag "T:Src64B, T:Myr1, Myristoylation sequence tag 1, Myristylation sequence tag 1, Src64B myristoylation sequence" 16-Dec-15 2015_12 FBgn0003046 Pcp Pupal cuticle protein http://flybase.net/reports/FBgn0003046.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008011=structural constituent of pupal chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelPcp, Pcpgart, Gart, DMCPGART, Gart intron gene, Gart intronic gene, CG3440" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG3440 16-Dec-15 2015_12 " pupal stage , larval stage | third instar , prepupal stage , prepupal stage | stage P4 " epidermis &&of larval abdomen

"partially lethal - majority die,some die during pupal stage" FBgn0263866 CR43713 http://flybase.net/reports/FBgn0263866.html non_protein_coding_gene lincRNA.47 CR43713 16-Dec-15 2015_12 FBgn0051896 tRNA:CR31896 transfer RNA:CR31896 http://flybase.net/reports/FBgn0051896.html "FBgn0011842, FBgn0060264" tRNA_gene "0033458=GAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:D:GTC:AE002690-a, chr2L.trna12-AspGTC, transfer RNA:asp2:29D, tRNA[[Asp]], tRNA:asp2:29D, tRNA:D2:29D, tRNA[Asp-GTC], AE002690.trna4-AspGTC, CR31896" CR31896 16-Dec-15 2015_12 FBgn0265877 CR44666 http://flybase.net/reports/FBgn0265877.html non_protein_coding_gene CR44666 16-Dec-15 2015_12 FBgn0037234 CG9795 http://flybase.net/reports/FBgn0037234.html FBan0009795 protein_coding_gene CG9795 16-Dec-15 2015_12 viable FBgn0004674 dv2 divergent 2 http://flybase.net/reports/FBgn0004674.html gene divergent II 16-Dec-15 2015_12 "visible,recessive" wing FBgn0060623 l(3)S087902 lethal (3) S087902 http://flybase.net/reports/FBgn0060623.html gene 0879/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0259175 ome omega http://flybase.net/reports/FBgn0259175.html "FBgn0002997, FBgn0036444, FBgn0040810, FBgn0042089, FBgn0052145, FBgn0052143" protein_coding_gene "0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0016020=membrane "CG32143, Ome, CG32145, CG17705, BEST:LD21715, CG42280, LD21715, CG9370" "IPR029058=Alpha/Beta hydrolase fold, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469=Dipeptidylpeptidase IV, N-terminal domain" CG42280 16-Dec-15 2015_12 "YHR028C(DAP2),YOR219C(STE13)" WBGene00001055(dpf-2) ENSXETG00000016197(dpp4) FBgn0053471 Ir48a Ionotropic receptor 48a http://flybase.net/reports/FBgn0053471.html pseudogene_attribute "CR33471, DmelIR48a, IR48a, ionotropic receptor 48a" CR33471 16-Dec-15 2015_12 FBgn0036520 CG13449 http://flybase.net/reports/FBgn0036520.html protein_coding_gene CG13449 16-Dec-15 2015_12 viable FBgn0011335 l(3)j2D3 lethal (3) j2D3 http://flybase.net/reports/FBgn0011335.html FBgn0036247 protein_coding_gene "CG6801, l(3)68Fb, L(3)JD3, l(3)jD3" IPR026095=Myb/SANT-like DNA-binding domain-containing protein CG6801 16-Dec-15 2015_12 "lethal,recessive" FBgn0034809 CG13542 http://flybase.net/reports/FBgn0034809.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028100 l(3)S072703b lethal (3) S072703b http://flybase.net/reports/FBgn0028100.html gene "0727/03, l(3)S072703" 16-Dec-15 2015_12 "lethal,recessive" FBgn0051723 CG31723 http://flybase.net/reports/FBgn0051723.html protein_coding_gene 16-Dec-15 2015_12 DRSC01141 K -0.910762608 -0.595567164 0.493725798 0.551923352 0.657179906 2.539360443 FBgn0069159 mcl(3)Z2094 mcl(3)Z2094 http://flybase.net/reports/FBgn0069159.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0035983 CG4080 http://flybase.net/reports/FBgn0035983.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0022416=chaeta development, 0000209=protein polyubiquitination, 0035220=wing disc development" "0031901=early endosome membrane, 0031902=late endosome membrane, 0005886=plasma membrane" 4080 "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011016=Zinc finger, RING-CH-type" CG4080 16-Dec-15 2015_12 viable FBgn0283468 slmb supernumerary limbs http://flybase.net/reports/FBgn0283468.html "FBgn0260565, FBgn0267841, FBgn0023423, FBgn0016060, FBgn0023437, FBgn0063206, FBgn0067639" protein_coding_gene "0051219=phosphoprotein binding, 0046983=protein dimerization activity, 0004842=ubiquitin-protein transferase activity" "0007611=learning or memory, 0008285=negative regulation of cell proliferation, 0030111=regulation of Wnt signaling pathway, 0006508=proteolysis, 0007298=border follicle cell migration, 0060623=regulation of chromosome condensation, 0008588=release of cytoplasmic sequestered NF-kappaB, 0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0045879=negative regulation of smoothened signaling pathway, 0030707=ovarian follicle cell development, 0030708=germarium-derived female germ-line cyst encapsulation, 0008355=olfactory learning, 0045451=pole plasm oskar mRNA localization, 0046599=regulation of centriole replication, 0030713=ovarian follicle cell stalk formation, 0007293=germarium-derived egg chamber formation, 0032007=negative regulation of TOR signaling, 0046843=dorsal appendage formation, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0046627=negative regulation of insulin receptor signaling pathway, 0060253=negative regulation of glial cell proliferation, 0030162=regulation of proteolysis, 0007309=oocyte axis specification, 0045475=locomotor rhythm, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0030727=germarium-derived female germ-line cyst formation, 0008589=regulation of smoothened signaling pathway, 0030178=negative regulation of Wnt signaling pathway, 0045849=negative regulation of nurse cell apoptotic process, 0016567=protein ubiquitination, 0090162=establishment of epithelial cell polarity, 0043066=negative regulation of apoptotic process, 2000114=regulation of establishment of cell polarity, 0007623=circadian rhythm, 0007304=chorion-containing eggshell formation, 0016322=neuron remodeling, 0007088=regulation of mitotic nuclear division" "0000151=ubiquitin ligase complex, 0019005=SCF ubiquitin ligase complex" "Slimb/beta-TRCP, CG3412, slimb, SLIMB, Supernumerary limbs, shiva, BcDNA:GM02031, wellman, MENE(3R)-B, wel, ica, Slimb/betaTrCP, Slimb, SLMB, l(3)00295, icare, Slmb, shv, MENE (3R)-B, Slimb/Beta-TRCP1, pingiel, centrosome replication defective, crd, FBXW1" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR001810=F-box domain, IPR019775=WD40 repeat, conserved site, IPR021977=D domain of beta-TrCP" CG3412 16-Dec-15 2015_12 "ENSDARG00000017230(fbxw11b),ENSDARG00000028543(fbxw11a)" YIL046W(MET30) WBGene00003009(lin-23) ENSXETG00000021199(btrc) "ENSMUSG00000025217(Btrc),ENSMUSG00000020271(Fbxw11)" "ENSG00000166167(BTRC),ENSG00000072803(FBXW11)" DRSC17056 K 0.177495942 0.401581989 -0.530153156 -0.969514645 0.821495136 2.735595372 FBgn0027495 CG8378 http://flybase.net/reports/FBgn0027495.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression "0005737=cytoplasm, 0005634=nucleus" BcDNA:LD29892 "IPR001214=SET domain, IPR011990=Tetratricopeptide-like helical domain, IPR002893=Zinc finger, MYND-type" CG8378 16-Dec-15 2015_12 ENSDARG00000060983(smynd4) YHR207C(SET5) WBGene00007403(set-3) ENSMUSG00000018809(Smyd4) viable FBgn0086540 MRE8 mRNA-like ncRNA in embryogenesis 8 http://flybase.net/reports/FBgn0086540.html non_protein_coding_gene GM07040 16-Dec-15 2015_12 FBgn0050091 CG30091 http://flybase.net/reports/FBgn0050091.html FBgn0034036 protein_coding_gene "0008236=serine-type peptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis CG8212 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG30091 16-Dec-15 2015_12 ENSDARG00000051929 viable FBgn0264382 CR43834 http://flybase.net/reports/FBgn0264382.html non_protein_coding_gene CR43834 16-Dec-15 2015_12 FBgn0264677 CR43962 http://flybase.net/reports/FBgn0264677.html non_protein_coding_gene lincRNA.1044 CR43962 16-Dec-15 2015_12 FBgn0029176 Ef1ë_ Ef1ë_ http://flybase.net/reports/FBgn0029176.html FBgn0039652 protein_coding_gene 0003746=translation elongation factor activity "0006414=translational elongation, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death" "0005875=microtubule associated complex, 0005853=eukaryotic translation elongation factor 1 complex, 0005811=lipid particle, 0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" "eEF1gamma, Ef1Bggr, CG11901, Ef1y, EF1gamma, Ef1gamma" "IPR004046=Glutathione S-transferase, C-terminal, IPR001662=Translation elongation factor EF1B, gamma chain, conserved, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG11901 16-Dec-15 2015_12 ENSDARG00000056119(eef1g) "YKL081W(TEF4),YPL048W(CAM1)" WBGene00008920(F17C11.9) ENSXETG00000026372(eef1g) ENSMUSG00000071644(Eef1g) ENSG00000186676 "viable,visible,recessive,lethal,wild-type,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,posterior compartment,eye,scutellar bristle,ectopic,somatic clone,ommatidium" DRSC16659 E 0.361479745 -0.722863215 2.169333932 -0.676437615 0.289683414 0.30027874 FBgn0263214 CR43384 http://flybase.net/reports/FBgn0263214.html pseudogene_attribute CR43384 16-Dec-15 2015_12 FBgn0001499 l(1)10Bm lethal (1) 10Bm http://flybase.net/reports/FBgn0001499.html gene "l9, l(1)L9, 9" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0043347 EP3707 EP3707 http://flybase.net/reports/FBgn0043347.html gene 16-Dec-15 2015_12 visible macrochaeta FBgn0005513 l(2)25Cg lethal (2) 25Cg http://flybase.net/reports/FBgn0005513.html gene "jf21, l(2)jf21" 16-Dec-15 2015_12 lethal FBgn0063298 CR31429 http://flybase.net/reports/FBgn0063298.html "FBgn0046070, FBgn0051429" non_protein_coding_gene "BcDNA:AT27571, NEST:bs10g06" CR31429 16-Dec-15 2015_12 FBgn0263648 CR43639 http://flybase.net/reports/FBgn0263648.html non_protein_coding_gene CR43639 16-Dec-15 2015_12 FBgn0267799 CR46124 http://flybase.net/reports/FBgn0267799.html non_protein_coding_gene CR46124 16-Dec-15 2015_12 FBgn0266835 CR45297 http://flybase.net/reports/FBgn0266835.html non_protein_coding_gene CR45297 16-Dec-15 2015_12 FBgn0065829 l(2)SH0354 lethal (2) SH0354 http://flybase.net/reports/FBgn0065829.html gene l(2)SH2 0354 16-Dec-15 2015_12 "lethal,recessive" FBgn0036729 CG13733 http://flybase.net/reports/FBgn0036729.html protein_coding_gene CG13733 16-Dec-15 2015_12 FBgn0011878 tRNA:H:48F transfer RNA:his:48F http://flybase.net/reports/FBgn0011878.html "FBgn0011876, FBgn0050252, FBgn0060204" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033426=CAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:His, chr2R.trna17-HisGTG, tRNA[His-48], tRNA:his:48F, tRNA[His], His-tRNA, tRNA:H:GTG:AE002787-e, AE002787.trna35-HisGTG, His-tRNA-gtg-gamma, CR30252" CR30252 16-Dec-15 2015_12 FBgn0086600 snoRNA:ë¬18S-1347c snoRNA:ë¬18S-1347c http://flybase.net/reports/FBgn0086600.html "FBgn0065075, FBgn0083052, FBgn0053633" snoRNA_gene 0005730=nucleolus "snoR203, psi18S-1347c, Dm-203, Psi18S-1347c, snoRNA:203, CR33633" CR33633 16-Dec-15 2015_12 FBgn0019657 sAM16 sAM16 http://flybase.net/reports/FBgn0019657.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0063905 Neurodegeneration-15 Neurodegeneration 15 http://flybase.net/reports/FBgn0063905.html gene ND15 16-Dec-15 2015_12 "paralytic,dominant" FBgn0036853 mRpL21 mitochondrial ribosomal protein L21 http://flybase.net/reports/FBgn0036853.html protein_coding_gene "0003723=RNA binding, 0003735=structural constituent of ribosome" "0006412=translation, 0032543=mitochondrial translation" 0005762=mitochondrial large ribosomal subunit "MRP-L21, CG9730" "IPR028909=Ribosomal protein L21-like, IPR001787=Ribosomal protein L21" CG9730 16-Dec-15 2015_12 ENSDARG00000003846(zgc:153377) YJL096W(MRPL49) WBGene00023422(F43C1.6) ENSXETG00000019978(TEgg142j23.1) ENSMUSG00000024829(Mrpl21) ENSG00000197345(MRPL21) "viable,visible" trichogen cell DRSC11100 K -0.528883467 -0.265772714 -0.135289884 0.37723743 1.608117376 0.02218506 FBgn0039817 CG15553 http://flybase.net/reports/FBgn0039817.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG15553 16-Dec-15 2015_12 ENSDARG00000026149(slc46a1) YJL163C() "WBGene00021159(Y4C6B.5),WBGene00009582(F40F9.5),WBGene00012811(Y43F8A.5)" ENSXETG00000023785(SLC46A1) "ENSMUSG00000020829(Slc46a1),ENSMUSG00000029650(Slc46a3)" "ENSG00000076351(SLC46A1),ENSG00000139508(SLC46A3)" "partially lethal - majority die,some die during pupal stage" FBgn0011480 l(3)neo47 lethal (3) neo47 http://flybase.net/reports/FBgn0011480.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0038296 CG6752 http://flybase.net/reports/FBgn0038296.html protein_coding_gene 0008270=zinc ion binding "IPR001841=Zinc finger, RING-type, IPR001870=B30.2/SPRY domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR003877=SPRY domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG6752 16-Dec-15 2015_12 ENSDARG00000031269(LOC568886) ENSXETG00000005952(RNF123) ENSMUSG00000041528(Rnf123) ENSG00000164068(RNF123) "viable,fertile" heart primordium FBgn0000811 fs(1)K79 female sterile (1) K79 http://flybase.net/reports/FBgn0000811.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "dorsal appendage,maternal effect" FBgn0060484 l(3)S110709b lethal (3) S110709b http://flybase.net/reports/FBgn0060484.html gene 1107/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0004629 Cys Cystatin-like http://flybase.net/reports/FBgn0004629.html "FBgn0004121, FBgn0062905" protein_coding_gene 0004869=cysteine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "CG8050, anon-EST:Liang-2.34, cystatin, Cystatin, BcDNA:RH72992, clone 2.34" "IPR000010=Cystatin domain, IPR020381=Proteinase inhibitor I25, cystatin, conserved region, IPR018073=Proteinase inhibitor I25, cystatin, conserved site" CG8050 16-Dec-15 2015_12 adult stage viable FBgn0051423 Ir94c Ionotropic receptor 94c http://flybase.net/reports/FBgn0051423.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG31423, DmelIR94c, ionotropic receptor 94c, IR94c" CG31423 16-Dec-15 2015_12 viable FBgn0259968 Sfp60F Seminal fluid protein 60F http://flybase.net/reports/FBgn0259968.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG42478, Seminal fluid protein 60F" CG42478 16-Dec-15 2015_12 FBgn0015478 l(2)45Bb lethal (2) 45Bb http://flybase.net/reports/FBgn0015478.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0061145 l(3)S000306 lethal (3) S000306 http://flybase.net/reports/FBgn0061145.html gene 6-Mar 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0086029 snoRNA:Me18S-A1597 http://flybase.net/reports/FBgn0086029.html snoRNA_gene "Me18S-Am1597, CR34658" CR34658 16-Dec-15 2015_12 FBgn0033887 St4 Sulfotransferase 4 http://flybase.net/reports/FBgn0033887.html protein_coding_gene 0008146=sulfotransferase activity "0051923=sulfation, 0006805=xenobiotic metabolic process" 0005829=cytosol "st4, CG6704, dmST4" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000863=Sulfotransferase domain" CG6704 16-Dec-15 2015_12 FBgn0262263 mir-969 mir-969 stem loop http://flybase.net/reports/FBgn0262263.html miRNA_gene 0007281=germ cell development "dme-mir-969, miR-969, CR42970" CR42970 16-Dec-15 2015_12 lethal "germline cell,maternal effect" FBgn0034505 CG16739 http://flybase.net/reports/FBgn0034505.html protein_coding_gene CG16739 16-Dec-15 2015_12 viable FBgn0015591 AstA Allatostatin A http://flybase.net/reports/FBgn0015591.html "FBgn0012040, FBgn0039220, FBgn0047160" protein_coding_gene "0005179=hormone activity, 0005184=neuropeptide hormone activity, 0071855=neuropeptide receptor binding" 0007218=neuropeptide signaling pathway 0005615=extracellular space "AstA-3, Ast-A, Drostatin-A1, ASA, AstA-1, DAP, Drostatin-A4, FGLa-type allatostatin, Drostatin-A2, Drm-AST-2, AstA-2, allatostatin-A-like, DST-3A, Ast, AstA-4, AST-1, allatostatin-A4, ALLS, allatostatin, DST-1A, drostatin-A2, Drm-AST-A, Allatostatin, DST-4A, AST-4, Drostatin-A3, allatostatin A-1, drostatin-A1, Drm-AST-3, drostatin-A3, Allatostatin A, Drm-AST-1, BcDNA:RE16553, Drm-AST-4, DAP-A, Allatostatin Diploptera-type, drostatin-A4, AS, AST, AST-3, CG13633, allatostatin A, AST-A, ast, DST-2A, AstA" IPR010276=Allatostatin CG13633 16-Dec-15 2015_12 viable FBgn0024508 l(3)01010 lethal (3) 01010 http://flybase.net/reports/FBgn0024508.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020332 anon-67EFa anon-67EFa http://flybase.net/reports/FBgn0020332.html gene "unnamed, 8H7" 16-Dec-15 2015_12 FBgn0050103 CG30103 http://flybase.net/reports/FBgn0050103.html "FBgn0034226, FBgn0065021" protein_coding_gene 0008253=5'-nucleotidase activity 0009166=nucleotide catabolic process "BcDNA:AT08275, CG4837" "IPR006179=5'-Nucleotidase/apyrase, IPR029052=Metallo-dependent phosphatase-like, IPR008334=5'-Nucleotidase, C-terminal, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG30103 16-Dec-15 2015_12 ENSDARG00000071017(LOC100334175) ENSXETG00000018096(NT5E) ENSMUSG00000032420(Nt5e) ENSG00000135318(NT5E) viable FBgn0031406 Send1 Spermathecal endopeptidase 1 http://flybase.net/reports/FBgn0031406.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP163, CG17012" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG17012 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0020328 anon-72BCa anon-72BCa http://flybase.net/reports/FBgn0020328.html gene "unnamed, 557" 16-Dec-15 2015_12 FBgn0014210 l(2)21Ca lethal (2) 21Ca http://flybase.net/reports/FBgn0014210.html gene 16-Dec-15 2015_12 "lethal,recessive,visible" FBgn0261838 pre-mod(mdg4)-Z http://flybase.net/reports/FBgn0261838.html protein_coding_gene CG42770 "IPR007588=Zinc finger, FLYWCH-type" CG42770 16-Dec-15 2015_12 FBgn0065600 l(2)SH0870 lethal (2) SH0870 http://flybase.net/reports/FBgn0065600.html gene l(2)SH2 0870 16-Dec-15 2015_12 "lethal,recessive" FBgn0051384 CR31384 http://flybase.net/reports/FBgn0051384.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0034860 CG9812 http://flybase.net/reports/FBgn0034860.html FBgn0062433 protein_coding_gene BcDNA:RH38235 CG9812 16-Dec-15 2015_12 "viable,fertile" FBgn0264472 CG43880 http://flybase.net/reports/FBgn0264472.html protein_coding_gene lincRNA.466 CG43880 16-Dec-15 2015_12 FBgn0014882 Ssb-c7a Single stranded-binding protein c7a http://flybase.net/reports/FBgn0014882.html gene c7a 16-Dec-15 2015_12 FBgn0000453 Dip-A Dipeptidase A http://flybase.net/reports/FBgn0000453.html gene "0008237=metallopeptidase activity, 0008240=tripeptidyl-peptidase activity, 0008239=dipeptidyl-peptidase activity" 0006508=proteolysis "Dip, Dipeptidase-A, DipA" 16-Dec-15 2015_12 electrophoretic variant FBgn0085353 CG34324 http://flybase.net/reports/FBgn0085353.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG12726 IPR002557=Chitin binding domain CG34324 16-Dec-15 2015_12 FBgn0060465 l(3)S114414b lethal (3) S114414b http://flybase.net/reports/FBgn0060465.html gene 1144/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0259448 EP-55 http://flybase.net/reports/FBgn0259448.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0062705 EP1065 EP1065 http://flybase.net/reports/FBgn0062705.html gene EP(2)1065 16-Dec-15 2015_12 FBgn0025000 E(vvl)23 E(vvl)23 http://flybase.net/reports/FBgn0025000.html gene "E(dfr)23, E(VVL)23" 16-Dec-15 2015_12 FBgn0263257 Cngl Cyclic nucleotide-gated ion channel-like http://flybase.net/reports/FBgn0263257.html "FBgn0030635, FBpp0073897, FBtr0074081, FBgn0030636, FBgn0029090" protein_coding_gene 0005221=intracellular cyclic nucleotide activated cation channel activity "0019935=cyclic-nucleotide-mediated signaling, 0006812=cation transport, 0055085=transmembrane transport" 0017071=intracellular cyclic nucleotide activated cation channel complex "cng-like, CNGL, dmCNG3, mdcds_55060, CNG channel-like, CG43395, CG18210, cngl, CG9176" "IPR018488=Cyclic nucleotide-binding, conserved site, IPR005821=Ion transport domain, IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like, IPR014710=RmlC-like jelly roll fold" CG43395 16-Dec-15 2015_12 "ENSDARG00000061685(hcn4),ENSDARG00000061665(hcn2),ENSDARG00000027192(si:ch211-130o18.2)" "ENSXETG00000017651(HCN3),ENSXETG00000005192(HCN4)" DRSC20318 IE 0.880695083 -3.482593379 2.007633778 -2.602725767 -0.480708544 0.030587315 FBgn0266564 CR45103 http://flybase.net/reports/FBgn0266564.html non_protein_coding_gene lincRNA.803 CR45103 16-Dec-15 2015_12 FBgn0002401 l(3)99Db lethal (3) 99Db http://flybase.net/reports/FBgn0002401.html gene 16-Dec-15 2015_12 lethal FBgn0065799 l(2)SH0412 lethal (2) SH0412 http://flybase.net/reports/FBgn0065799.html gene l(2)SH2 0412 16-Dec-15 2015_12 "lethal,recessive" FBgn0051547 CG31547 http://flybase.net/reports/FBgn0051547.html "FBgn0037335, FBgn0040680" protein_coding_gene "0015171=amino acid transmembrane transporter activity, 0008511=sodium:potassium:chloride symporter activity" "0003333=amino acid transmembrane transport, 0006810=transport" 0016021=integral component of membrane "CG2509, CG10544" "IPR004842=SLC12A transporter family, IPR018491=SLC12A transporter, C-terminal, IPR004841=Amino acid permease/ SLC12A domain" CG31547 16-Dec-15 2015_12 "ENSDARG00000013855(slc12a3),ENSDARG00000013743(LOC100003286),ENSDARG00000055313(slc12a10.1),ENSDARG00000055253(slc12a10.3),ENSDARG00000071173(slc12a10.2)" WBGene00012543(nkcc-1) viable FBgn0005173 l(2)M lethal of Mohr http://flybase.net/reports/FBgn0005173.html gene lethal (2) from Mohr 16-Dec-15 2015_12 lethal FBgn0015694 E(Sxl) Enhancer of Sex-lethal http://flybase.net/reports/FBgn0015694.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037396 CG11459 http://flybase.net/reports/FBgn0037396.html protein_coding_gene "0008234=cysteine-type peptidase activity, 0004197=cysteine-type endopeptidase activity" 0006508=proteolysis "IPR000668=Peptidase C1A, papain C-terminal, IPR013128=Peptidase C1A, IPR025660=Cysteine peptidase, histidine active site, IPR013201=Cathepsin propeptide inhibitor domain (I29)" CG11459 16-Dec-15 2015_12 viable FBgn0053325 CG33325 http://flybase.net/reports/FBgn0053325.html protein_coding_gene CG33325 16-Dec-15 2015_12 viable FBgn0035455 CG10862 http://flybase.net/reports/FBgn0035455.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0000209=protein polyubiquitination, 0032504=multicellular organism reproduction" 0005615=extracellular space "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG10862 16-Dec-15 2015_12 viable FBgn0265400 EP2161 http://flybase.net/reports/FBgn0265400.html gene 16-Dec-15 2015_12 FBgn0260572 MENE-W12 http://flybase.net/reports/FBgn0260572.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0042130 CG18807 http://flybase.net/reports/FBgn0042130.html protein_coding_gene 16-Dec-15 2015_12 FBgn0020624 PZ22 PZ22 http://flybase.net/reports/FBgn0020624.html gene 16-Dec-15 2015_12 FBgn0069952 CG41071 http://flybase.net/reports/FBgn0069952.html protein_coding_gene CG40168 16-Dec-15 2015_12 FBgn0052633 CG32633 http://flybase.net/reports/FBgn0052633.html "FBgn0030496, FBgn0044714" protein_coding_gene "CG1733, anon-WO0140519.164" "IPR024518=Domain of unknown function DUF3421, IPR006616=DM9 repeat" CG32633 16-Dec-15 2015_12 FBgn0065765 l(2)SH0474 lethal (2) SH0474 http://flybase.net/reports/FBgn0065765.html gene l(2)SH2 0474 16-Dec-15 2015_12 "lethal,recessive" FBgn0036491 Best4 Bestrophin 4 http://flybase.net/reports/FBgn0036491.html protein_coding_gene 0005254=chloride channel activity 0006821=chloride transport 0005887=integral component of plasma membrane "CT22395, dBest4, CG7259, dbest4" "IPR000615=Bestrophin, IPR021134=Bestrophin/UPF0187" CG7259 16-Dec-15 2015_12 "WBGene00022797(ZK688.2),WBGene00007203(B0564.3),WBGene00011868(T20G5.4),WBGene00007204(B0564.4),WBGene00007808(C29F4.2),WBGene00007404(C07A9.8),WBGene00013921(ZC518.1),WBGene00011258(R13.3)" "ENSXETG00000013592(BEST4),ENSXETG00000025368(BC061379.1),ENSXETG00000001407(BEST3),ENSXETG00000006740(BEST1)" "ENSMUSG00000052819(Best2),ENSMUSG00000020169(Best3),ENSMUSG00000037418(Best1)" "ENSG00000039987(BEST2),ENSG00000127325(BEST3),ENSG00000142959(BEST4),ENSG00000167995(BEST1)" viable FBgn0264836 CG44044 http://flybase.net/reports/FBgn0264836.html protein_coding_gene CG44044 16-Dec-15 2015_12 FBgn0042145 CG18822 http://flybase.net/reports/FBgn0042145.html protein_coding_gene 16-Dec-15 2015_12 FBgn0023408 Ars-region52 Autonomous replicating sequence region 52 http://flybase.net/reports/FBgn0023408.html region "Ars52, dARS52" 16-Dec-15 2015_12 FBgn0069122 ms(2)Z2181 ms(2)Z2181 http://flybase.net/reports/FBgn0069122.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile spermatozoon FBgn0022246 Rpp30 RNaseP protein p30 http://flybase.net/reports/FBgn0022246.html FBgn0031237 protein_coding_gene 0004540=ribonuclease activity "0008033=tRNA processing, 0022008=neurogenesis" 0030677=ribonuclease P complex "CG11606, l(2)k01901, RNase P, #19/1" "IPR002738=RNase P subunit p30, IPR016195=Polymerase/histidinol phosphatase-like" CG11606 16-Dec-15 2015_12 ENSDARG00000027428(rpp30) YHR062C(RPP1) WBGene00019264(H35B03.2) ENSXETG00000021785(rpp30) ENSMUSG00000024800(Rpp30) ENSG00000148688(RPP30) "lethal,recessive,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0020612 Ufo Ultra female overexpression http://flybase.net/reports/FBgn0020612.html gene 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation" pigment cell FBgn0035603 CG10635 http://flybase.net/reports/FBgn0035603.html FBgn0062885 protein_coding_gene "0051087=chaperone binding, 0051082=unfolded protein binding" "0006457=protein folding, 0006458='de novo' protein folding" 0016272=prefoldin complex BcDNA:SD11994 "IPR016661=Prefoldin, subunit 4, IPR002777=Prefoldin beta-like, IPR009053=Prefoldin" CG10635 16-Dec-15 2015_12 ENSDARG00000061228(LOC572231) YNL153C(GIM3) WBGene00007107(pfd-4) ENSXETG00000017525(PFDN4) ENSMUSG00000052033(Pfdn4) ENSG00000101132(PFDN4) "viable,body color defective" mesothoracic tergum FBgn0262194 mir-2489 mir-2489 stem loop http://flybase.net/reports/FBgn0262194.html miRNA_gene "miR-2489, CR42901, dme-mir-2489" CR42901 16-Dec-15 2015_12 viable FBgn0263200 Galt Galactose-1-phosphate uridylyltransferase http://flybase.net/reports/FBgn0263200.html "FBgn0262939, FBgn0031845" protein_coding_gene "0008108=UDP-glucose:hexose-1-phosphate uridylyltransferase activity, 0008270=zinc ion binding" "0008344=adult locomotory behavior, 0033501=galactose homeostasis, 0006012=galactose metabolic process" "CG9232, dGALT, galactose-1-phosphate uridylyltransferase, galactose-1P uridylyltransferase, GALT" "IPR019779=Galactose-1-phosphate uridyl transferase, class I His-active site, IPR005850=Galactose-1-phosphate uridyl transferase, C-terminal, IPR011146=HIT-like domain, IPR005849=Galactose-1-phosphate uridyl transferase, N-terminal, IPR001937=Galactose-1-phosphate uridyl transferase, class I" CG9232 16-Dec-15 2015_12 ENSDARG00000069543(zgc:158795) YBR018C(GAL7) WBGene00014203(ZK1058.3) ENSMUSG00000036073(Galt) ENSG00000213930(GALT) FBgn0039654 Brd8 Bromodomain containing 8 http://flybase.net/reports/FBgn0039654.html protein_coding_gene "0043486=histone exchange, 0016573=histone acetylation, 0010629=negative regulation of gene expression" 0035267=NuA4 histone acetyltransferase complex "Brd8, CG14514, dBrd8" IPR001487=Bromodomain CG14514 16-Dec-15 2015_12 "ENSDARG00000025071(brd8),ENSDARG00000055999(LOC100003763)" ENSXETG00000006726(BRD8) ENSMUSG00000003778(Brd8) ENSG00000112983(BRD8) viable DRSC28811 K -1.414981366 -1.538080134 FBgn0032170 CG4658 http://flybase.net/reports/FBgn0032170.html protein_coding_gene IPR006571=TLDc domain CG4658 16-Dec-15 2015_12 WBGene00021442(Y39A3CL.4) "viable,fertile" FBgn0011130 l(1)Q204 lethal (1) Q204 http://flybase.net/reports/FBgn0011130.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0062655 EP344 EP344 http://flybase.net/reports/FBgn0062655.html gene EP(3)0344 16-Dec-15 2015_12 FBgn0035076 Ance-5 Ance-5 http://flybase.net/reports/FBgn0035076.html protein_coding_gene "0008233=peptidase activity, 0008237=metallopeptidase activity, 0008241=peptidyl-dipeptidase activity" 0006508=proteolysis 0016020=membrane "CG10142, ance-5" "IPR001548=Peptidase M2, peptidyl-dipeptidase A" CG10142 16-Dec-15 2015_12 viable FBgn0015916 bk87 bk87 http://flybase.net/reports/FBgn0015916.html gene 16-Dec-15 2015_12 FBgn0016641 PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 http://flybase.net/reports/FBgn0016641.html protein_coding_gene 0004725=protein tyrosine phosphatase activity "0000188=inactivation of MAPK activity, 0007465=R7 cell fate commitment, 0070373=negative regulation of ERK1 and ERK2 cascade, 0000278=mitotic cell cycle, 0007265=Ras protein signal transduction, 0046580=negative regulation of Ras protein signal transduction, 0006470=protein dephosphorylation" 0005737=cytoplasm "Protein tyrosine phosphatase, CG9856, ptp-er, ER2-5" "IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain, IPR000242=PTP type protein phosphatase" CG9856 16-Dec-15 2015_12 "ENSMUSG00000020151(Ptprr),ENSMUSG00000030854(Ptpn5)" "ENSG00000153233(PTPRR),ENSG00000110786(PTPN5),ENSG00000143851(PTPN7)" "viable,fertile,visible,recessive,lethal" "photoreceptor cell R7,ectopic,eye,eye photoreceptor cell,ommatidium,supernumerary" DRSC04636 IEK 2.41765926 0.824558718 2.32666375 -0.443680677 2.721199158 1.701721534 FBgn0000726 Frd Freckled http://flybase.net/reports/FBgn0000726.html gene 16-Dec-15 2015_12 "lethal,recessive,body color defective,dominant" "fat body,pericardial cell" FBgn0000074 amb amber http://flybase.net/reports/FBgn0000074.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,male fertile,female sterile,body color defective,male sterile,eye color defective,poor" "macrochaeta,pigment cell" FBgn0004996 Cr-2 Cream 2 http://flybase.net/reports/FBgn0004996.html gene Cream in chromosome 2 16-Dec-15 2015_12 eye color defective pigment cell FBgn0024265 acd(2)5G23 auditory courtship defective 5G23 http://flybase.net/reports/FBgn0024265.html gene "0031223=auditory behavior, 0008049=male courtship behavior" "5G23, unnamed" 16-Dec-15 2015_12 "viable,auditory perception defective,courtship behavior defective,male fertile" FBgn0259359 C518 http://flybase.net/reports/FBgn0259359.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,chaeta" FBgn0011234 tmx trail mix http://flybase.net/reports/FBgn0011234.html gene 0007286=spermatid development ms(2)05235 16-Dec-15 2015_12 "male sterile,recessive" FBgn0060924 l(3)S042207 lethal (3) S042207 http://flybase.net/reports/FBgn0060924.html gene 0422/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0061065 l(3)S020802b lethal (3) S020802b http://flybase.net/reports/FBgn0061065.html gene 0208/02 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0263038 CG43333 http://flybase.net/reports/FBgn0263038.html "FBgn0052972, FBan0032972, FBgn0028905" protein_coding_gene "BG:DS01523.2, CG15291, CG32972" IPR000782=FAS1 domain CG43333 16-Dec-15 2015_12 "viable,fertile,lethal" FBgn0016811 l(1)L12 lethal (1) L12 http://flybase.net/reports/FBgn0016811.html gene L12 16-Dec-15 2015_12 "lethal,recessive" FBgn0005329 P43 P43 http://flybase.net/reports/FBgn0005329.html gene 16-Dec-15 2015_12 "optomotor response defective,neurophysiology defective,neuroanatomy defective,phototaxis defective,behavior defective" "optic lobe,brain,lamina" FBgn0260493 l(3)2332 http://flybase.net/reports/FBgn0260493.html gene 0007409=axonogenesis 16-Dec-15 2015_12 neuroanatomy defective dendritic arborizing neuron FBgn0004519 l(4)102CDc lethal (4) 102CDc http://flybase.net/reports/FBgn0004519.html gene "l(4)4, lethal(4) Powell, Tennessee-3, l(4)PT-3, l(4)AM-2, l(4)18" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0065698 l(2)SH0627 lethal (2) SH0627 http://flybase.net/reports/FBgn0065698.html gene l(2)SH2 0627 16-Dec-15 2015_12 "lethal,recessive" FBgn0020891 Su(osk)M26 Suppressor of oskar M26 http://flybase.net/reports/FBgn0020891.html gene M26 16-Dec-15 2015_12 FBgn0028499 CG7985 http://flybase.net/reports/FBgn0028499.html protein_coding_gene 0005975=carbohydrate metabolic process 0005739=mitochondrion BcDNA:GH04120 "IPR013781=Glycoside hydrolase, catalytic domain, IPR017853=Glycoside hydrolase superfamily" CG7985 16-Dec-15 2015_12 "ENSDARG00000061216(zgc:152869),ENSDARG00000038242(zgc:113333)" "WBGene00012663(hex-3),WBGene00015767(hex-2),WBGene00013497(hex-5)" ENSXETG00000012232(HEXDC) ENSMUSG00000039307(Hexdc) "viable,fertile" FBgn0031089 CG9572 http://flybase.net/reports/FBgn0031089.html protein_coding_gene CT17356 "IPR013032=EGF-like, conserved site, IPR000742=EGF-like domain" CG9572 16-Dec-15 2015_12 "WBGene00018906(F55G1.13),WBGene00013487(tag-336),WBGene00013486(Y69H2.11),WBGene00013480(Y69H2.2)" FBgn0036799 CG13380 http://flybase.net/reports/FBgn0036799.html protein_coding_gene CG13380 16-Dec-15 2015_12 FBgn0013683 mt:ND4L mitochondrial NADH-ubiquinone oxidoreductase chain 4L http://flybase.net/reports/FBgn0013683.html FBgn0002867 protein_coding_gene "0016651=oxidoreductase activity, acting on NAD(P)H, 0008137=NADH dehydrogenase (ubiquinone) activity" 0042773=ATP synthesis coupled electron transport "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "nad4L, URF4L, ND4L, CG34086, nd4L" IPR001133=NADH-ubiquinone oxidoreductase chain 4L/K CG34086 16-Dec-15 2015_12 ENSDARG00000063916 ENSMUSG00000067736(Gm10222) FBgn0053797 CR33797 http://flybase.net/reports/FBgn0053797.html pseudogene_attribute CG33797 CR33797 16-Dec-15 2015_12 FBgn0005008 dil-3 dilute 3 http://flybase.net/reports/FBgn0005008.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0060624 l(3)S087607b lethal (3) S087607b http://flybase.net/reports/FBgn0060624.html gene 0876/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0058262 CG40262 http://flybase.net/reports/FBgn0058262.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040886 CG12528 http://flybase.net/reports/FBgn0040886.html protein_coding_gene 16-Dec-15 2015_12 FBgn0052816 CG32816 http://flybase.net/reports/FBgn0052816.html protein_coding_gene CG32816 16-Dec-15 2015_12 viable FBgn0260594 2L1683 http://flybase.net/reports/FBgn0260594.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0028741 fab1 http://flybase.net/reports/FBgn0028741.html protein_coding_gene "0000285=1-phosphatidylinositol-3-phosphate 5-kinase activity, 0008270=zinc ion binding, 0005524=ATP binding, 0016308=1-phosphatidylinositol-4-phosphate 5-kinase activity" "0016310=phosphorylation, 0035556=intracellular signal transduction, 0008333=endosome to lysosome transport, 0000046=autophagic vacuole fusion, 0046854=phosphatidylinositol phosphorylation" "0005768=endosome, 0012506=vesicle membrane" "fab-1, PtdIns3P, EG:52C10.5, Fab1, PtdIns(3)P 5-kinase, PIKfyve, l(2)SJB, CG6355" "IPR011011=Zinc finger, FYVE/PHD-type, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000591=DEP domain, IPR027483=Phosphatidylinositol-4-phosphate 5-kinase, C-terminal, IPR027409=GroEL-like apical domain, IPR027484=Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR002498=Phosphatidylinositol-4-phosphate 5-kinase, core, IPR000306=FYVE zinc finger, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR016034=Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup, IPR017455=Zinc finger, FYVE-related" CG6355 16-Dec-15 2015_12 ENSDARG00000056112(pikfyve) YFR019W(FAB1) WBGene00004089(ppk-3) ENSXETG00000025548() ENSMUSG00000025949(Pikfyve) ENSG00000115020(PIKFYVE) "lethal - all die before end of P-stage,some die during pharate adult stage,size defective,somatic clone,large body" "eye disc,eye,somatic clone,ommatidium,adult head,imaginal disc,embryonic/larval garland cell,endosome14H10W-30)" FBgn0065565 l(2)SH0980 lethal (2) SH0980 http://flybase.net/reports/FBgn0065565.html gene l(2)SH2 0980 16-Dec-15 2015_12 "lethal,recessive" FBgn0264746 CG44004 http://flybase.net/reports/FBgn0264746.html FBgn0085281 protein_coding_gene CG34252 IPR001810=F-box domain CG44004 16-Dec-15 2015_12 FBgn0013265 E(var)71 E(var)71 http://flybase.net/reports/FBgn0013265.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0040040 CG17613 http://flybase.net/reports/FBgn0040040.html protein_coding_gene 16-Dec-15 2015_12 FBgn0084640 Su(dpp)YE2 Su(dpp)YE2 http://flybase.net/reports/FBgn0084640.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,amnioserosa" FBgn0038316 CG6276 http://flybase.net/reports/FBgn0038316.html protein_coding_gene 0003677=DNA binding "IPR006578=MADF domain, IPR004210=BESS motif" CG6276 16-Dec-15 2015_12 "viable,fertile" FBgn0265922 CR44711 http://flybase.net/reports/FBgn0265922.html non_protein_coding_gene lincRNA.1038 CR44711 16-Dec-15 2015_12 FBgn0060423 l(3)S127704a lethal (3) S127704a http://flybase.net/reports/FBgn0060423.html gene 1277/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0014286 l(3)64Ae lethal (3) 64Ae http://flybase.net/reports/FBgn0014286.html gene l(3)SH20 16-Dec-15 2015_12 "lethal,recessive" FBgn0024272 ZAM\env env http://flybase.net/reports/FBgn0024272.html transposable_element_gene "ORF3, ZAM env, env" IPR009882=Gypsy 16-Dec-15 2015_12 FBgn0026427 Su(var)2-HP2 Su(var)2-HP2 http://flybase.net/reports/FBgn0026427.html FBgn0033946 protein_coding_gene 0003677=DNA binding "0016458=gene silencing, 0031507=heterochromatin assembly, 0022008=neurogenesis, 0007076=mitotic chromosome condensation, 0051276=chromosome organization" "0000775=chromosome, centromeric region, 0000792=heterochromatin, 0000793=condensed chromosome, 0005700=polytene chromosome, 0005720=nuclear heterochromatin" "SU(VAR)2-HP2, CG12864, Heterochromatin Protein 2, Hp2, Heterochromatin protein 2, HP2, Heterochromatic Protein 2" "IPR017956=AT hook, DNA-binding motif" CG12864 16-Dec-15 2015_12 "lethal,non-suppressor of variegation,suppressor of variegation,dominant,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed chromosomeB11),polytene chromosomeB11),ganglion mother cell,mesothoracic tergum" FBgn0004207 l(3)84Ee lethal (3) 84Ee http://flybase.net/reports/FBgn0004207.html gene 16-Dec-15 2015_12 lethal FBgn0263939 BG00028 http://flybase.net/reports/FBgn0263939.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0030691 Efhc1.1 EFHC1 homologue 1 http://flybase.net/reports/FBgn0030691.html protein_coding_gene "0051124=synaptic growth at neuromuscular junction, 0048814=regulation of dendrite morphogenesis" "0043025=neuronal cell body, 0005874=microtubule, 0043195=terminal bouton, 0030425=dendrite" "CG8959, EFHC1 homolog, Defhc1.1" "IPR010554=Protein of unknown function DUF1126, IPR006602=Uncharacterised domain DM10" CG8959 16-Dec-15 2015_12 ENSDARG00000004204(efhc2) WBGene00013028(Y49A10A.1) ENSXETG00000000659(Q66IK9_XENTR) ENSMUSG00000025038(Efhc2) ENSG00000183690(EFHC2) "neuroanatomy defective,viable,recessive,neurophysiology defective" "dendritic arborizing neuron | third instar larval stage,NMJ bouton,embryonic/larval neuromuscular junction,synapse | third instar larval stage,dendritic arborizing neuron" FBgn0028576 pp10 pp10 http://flybase.net/reports/FBgn0028576.html gene 16-Dec-15 2015_12 FBgn0044336 May-68 May-68 http://flybase.net/reports/FBgn0044336.html gene 16-Dec-15 2015_12 "uncoordinated,recessive,locomotor behavior defective,behavior defective" FBgn0260498 l(3)11534 http://flybase.net/reports/FBgn0260498.html gene 16-Dec-15 2015_12 neuroanatomy defective dendritic arborizing neuron FBgn0002845 M(Sd) Modifier of Sd http://flybase.net/reports/FBgn0002845.html gene M(SD) 16-Dec-15 2015_12 FBgn0053509 CG33509 http://flybase.net/reports/FBgn0053509.html "FBgn0032912, FBtr0081506, FBpp0081034" protein_coding_gene CG14398 "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG33509 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" viable FBgn0020234 Ace::Nrt Ace::Nrt http://flybase.net/reports/FBgn0020234.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0020793 otri oculi triangulares http://flybase.net/reports/FBgn0020793.html gene occhi triangolari 16-Dec-15 2015_12 "visible,viable" ommatidium FBgn0026736 anon-C2 anon-C2 http://flybase.net/reports/FBgn0026736.html gene C2 16-Dec-15 2015_12 FBgn0029014 l(3)77CDk lethal (3) 77CDk http://flybase.net/reports/FBgn0029014.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive,visible" macrochaeta FBgn0259926 CG42449 http://flybase.net/reports/FBgn0259926.html FBgn0029788 protein_coding_gene CG15778 CG42449 16-Dec-15 2015_12 FBgn0025785 anon-MMS128 anon-MMS128 http://flybase.net/reports/FBgn0025785.html gene 16-Dec-15 2015_12 FBgn0025555 anon-88Bc anon-88Bc http://flybase.net/reports/FBgn0025555.html gene c1.0/c1.2 16-Dec-15 2015_12 FBgn0087007 bbg big bang http://flybase.net/reports/FBgn0087007.html "FBgn0036425, FBgn0036424, FBgn0024488, FBan0009598" protein_coding_gene "0002227=innate immune response in mucosa, 0007444=imaginal disc development, 0007298=border follicle cell migration" "0005918=septate junction, 0045177=apical part of cell, 0005634=nucleus" "CG42230, BBG, CG9587, CG9598, C96" IPR001478=PDZ domain CG42230 16-Dec-15 2015_12 "ENSMUSG00000001741(Il16),ENSMUSG00000022197(Pdzd2)" FBgn0259523 B2003 http://flybase.net/reports/FBgn0259523.html gene 16-Dec-15 2015_12 "visible,lethal" "tarsal segment,arista" FBgn0044031 Mod(rst)K58 Mod(rst)K58 http://flybase.net/reports/FBgn0044031.html gene 0001745=compound eye morphogenesis K58 16-Dec-15 2015_12 viable FBgn0263571 mir-4959 mir-4959 stem loop http://flybase.net/reports/FBgn0263571.html miRNA_gene "CR43556, dme-mir-4959" CR43556 16-Dec-15 2015_12 FBgn0033876 Syngr Synaptogyrin http://flybase.net/reports/FBgn0033876.html protein_coding_gene "0022008=neurogenesis, 0017158=regulation of calcium ion-dependent exocytosis, 0048489=synaptic vesicle transport, 0016079=synaptic vesicle exocytosis" 0016020=membrane "synaptogyrin, Gyr, sng-1, CG10808, Synaptogyrin, gyr" "IPR016579=Synaptogyrin, IPR008253=Marvel domain" CG10808 16-Dec-15 2015_12 "ENSDARG00000002564(syngr1a),ENSDARG00000023209(syngr1b),ENSDARG00000014871(syngr3),ENSDARG00000025034(zgc:165621),ENSDARG00000052429(syngr2a)" WBGene00004912(sng-1) "ENSXETG00000006915(syngr1),ENSXETG00000022670(SYNGR3),ENSXETG00000001322(syngr2)" "ENSMUSG00000022415(Syngr1),ENSMUSG00000007021(Syngr3),ENSMUSG00000048277(Syngr2)" "ENSG00000100321(SYNGR1),ENSG00000127561(SYNGR3),ENSG00000108639(SYNGR2)" "viable,fertile,neuroanatomy defective,lethal,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuromuscular junction,NMJ bouton,endocytic vesicle,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0260075 2L1360 http://flybase.net/reports/FBgn0260075.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0260022 corona-2 corona on 2 http://flybase.net/reports/FBgn0260022.html gene corona 16-Dec-15 2015_12 chorion | germline clone FBgn0264945 CR44114 http://flybase.net/reports/FBgn0264945.html non_protein_coding_gene CR44114 16-Dec-15 2015_12 FBgn0031476 CG8813 http://flybase.net/reports/FBgn0031476.html FBgn0044529 protein_coding_gene anon-WO0140519.96 CG8813 16-Dec-15 2015_12 viable FBgn0065926 l(2)SH0145 lethal (2) SH0145 http://flybase.net/reports/FBgn0065926.html gene l(2)SH2 0145 16-Dec-15 2015_12 "lethal,recessive" FBgn0035131 mthl9 methuselah-like 9 http://flybase.net/reports/FBgn0035131.html "FBgn0046576, FBgn0046577" protein_coding_gene 0004930=G-protein coupled receptor activity "0008340=determination of adult lifespan, 0007186=G-protein coupled receptor signaling pathway, 0042594=response to starvation" 0016021=integral component of membrane "CG17084, Mth-like 9, anon-WO0170980.163, mth-like 9, Mth-9, anon-WO0170980.164" "IPR010596=Methuselah, N-terminal domain, IPR023311=Methuselah ectodomain, domain 2" CG17084 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" viable DRSC08506 K 0.299797719 -0.116957227 -0.568413851 0.567150131 2.238021245 -0.10575659 FBgn0038558 CG12347 http://flybase.net/reports/FBgn0038558.html protein_coding_gene CG12347 16-Dec-15 2015_12 viable FBgn0026754 Ugt37c1 UDP-glycosyltransferase 37c1 http://flybase.net/reports/FBgn0026754.html FBgn0025831 protein_coding_gene "0050488=ecdysteroid UDP-glucosyltransferase activity, 0008194=UDP-glycosyltransferase activity, 0016758=transferase activity, transferring hexosyl groups" 0006011=UDP-glucose metabolic process 0016021=integral component of membrane "EG:EG0003.4, DmeUgt37c1, LD15335, CG8652, AC 004641A" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG8652 16-Dec-15 2015_12 "WBGene00011006(ugt-47),WBGene00011564(ugt-50),WBGene00015141(ugt-46),WBGene00015965(ugt-48),WBGene00007070(ugt-49)" viable FBgn0278608 Dsp1 Dorsal switch protein 1 http://flybase.net/reports/FBgn0278608.html "FBgn0011764, FBgn0015237, FBgn0015301, FBgn0019980" protein_coding_gene "0017025=TBP-class protein binding, 0008134=transcription factor binding, 0008301=DNA binding, bending, 0003677=DNA binding" "0032502=developmental process, 0035218=leg disc development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007379=segment specification, 0017055=negative regulation of RNA polymerase II transcriptional preinitiation complex assembly, 0006338=chromatin remodeling, 0008348=negative regulation of antimicrobial humoral response, 0043388=positive regulation of DNA binding" "0005700=polytene chromosome, 0005634=nucleus" "Ssrp2, hmg, CG12223, Dorsal Switch Protein 1, Hmg14B, ssrp2, Hmg14D, dsp1, Dorsal switch protein-1, DSP1, Structure specific recognition protein 2" "IPR009071=High mobility group box domain, IPR017967=HMG box A DNA-binding domain, conserved site" CG12223 16-Dec-15 2015_12 "ENSDARG00000030479(zgc:165618),ENSDARG00000029722(hmgb2),ENSDARG00000056725(hmgb3a),ENSDARG00000006408(hmgb3b),ENSDARG00000053994(LOC100332676),ENSDARG00000053990(hmgb2l)" "ENSXETG00000019166(hmgb1),ENSXETG00000007740(hmgb3),ENSXETG00000016916(HMGB2)" "ENSMUSG00000066551(Hmgb1),ENSMUSG00000066530,ENSMUSG00000070058,ENSMUSG00000054717(Hmgb2),ENSMUSG00000062477(Hmgb1l),ENSMUSG00000015217(Hmgb3)" "ENSG00000189403(HMGB1),ENSG00000124097,ENSG00000164104(HMGB2),ENSG00000029993(HMGB3),ENSG00000132967" "visible,neuroanatomy defective,lethal,flight defective,recessive,sterile,partially,fertile,poor,homeotic,viable,locomotor behavior defective,wild-type" "wing,scutellum,adult thorax,dorsal,eye,intersegmental nerve,anterior fascicle & synapse,haltere,egg,abdominal 5 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic/first instar larval cuticle,prothoracic leg,metathoracic leg,ectopic,sex comb,metathoracic laterotergite,scutum,adult abdominal segment 6,adult abdominal segment 5,adult abdominal segment 4,abdominal sternite bristle,metathoracic segment,anterior compartment" DRSC23078 K -1.782546655 -1.832569564 FBgn0040959 Peritrophin-15a Peritrophin-15a http://flybase.net/reports/FBgn0040959.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process "0005615=extracellular space, 0005576=extracellular region" "Dm15a, Dm-peritrophin-15a, CG17814, CT39472" IPR002557=Chitin binding domain CG17814 16-Dec-15 2015_12 viable FBgn0045962 Stalker\ORF1 ORF1 http://flybase.net/reports/FBgn0045962.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR015416=Zinc finger, H2C2-type, histone UAS binding, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0037684 CG8129 http://flybase.net/reports/FBgn0037684.html protein_coding_gene 0004794=L-threonine ammonia-lyase activity "CT24308, Serine racemase" IPR001926=Tryptophan synthase beta subunit-like PLP-dependent enzyme CG8129 16-Dec-15 2015_12 YKL218C(SRY1) WBGene00010456(K01C8.1) ENSXETG00000027747() ENSMUSG00000001323(Srr) ENSG00000167720(SRR) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0265276 l(3)neo38 lethal (3) neo38 http://flybase.net/reports/FBgn0265276.html "FBgn0086910, FBan0006930, FBgn0037947, FBgn0011471, FBgn0051364, FBgn0062876, FBgn0037948, FBgn0022340" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0031935=regulation of chromatin silencing, 0007476=imaginal disc-derived wing morphogenesis" 0005634=nucleus "BcDNA:SD16005, CG14725, anon-fast-evolving-2F4, CG31364, anon-EST:fe2F4, anon2F4, CG6930" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR027775=C2H2- zinc finger protein family" CG6930 16-Dec-15 2015_12 WBGene00000483(che-1) FBgn0039544 CG12877 http://flybase.net/reports/FBgn0039544.html FBgn0064921 protein_coding_gene 0003676=nucleic acid binding BcDNA:LD30051 "IPR012337=Ribonuclease H-like domain, IPR013520=Exonuclease, RNase T/DNA polymerase III" CG12877 16-Dec-15 2015_12 ENSDARG00000026986(rexo1) WBGene00004095(pqe-1) ENSXETG00000008146() ENSMUSG00000047417(Rexo1) ENSG00000079313(REXO1) "viable,fertile" FBgn0052567 CG32567 http://flybase.net/reports/FBgn0052567.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053382 5SrRNA:CR33382 5SrRNA:CR33382 http://flybase.net/reports/FBgn0053382.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33382 CR33382 16-Dec-15 2015_12 FBgn0065385 l(2)SH1637 lethal (2) SH1637 http://flybase.net/reports/FBgn0065385.html gene l(2)SH2 1637 16-Dec-15 2015_12 "lethal,recessive" FBgn0267281 CR45717 http://flybase.net/reports/FBgn0267281.html non_protein_coding_gene CR45717 16-Dec-15 2015_12 FBgn0038682 CG5835 http://flybase.net/reports/FBgn0038682.html protein_coding_gene CG5835 16-Dec-15 2015_12 "viable,fertile" FBgn0000262 cau cauliflower http://flybase.net/reports/FBgn0000262.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/larval midgut,embryonic/first instar larval cuticle,embryonic Malpighian tubule" FBgn0032138 CG4364 http://flybase.net/reports/FBgn0032138.html protein_coding_gene "0000463=maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0022008=neurogenesis" "0005654=nucleoplasm, 0005730=nucleolus" "IPR001357=BRCT domain, IPR010613=Pescadillo" CG4364 16-Dec-15 2015_12 YGR103W(NOP7) WBGene00003063(lpd-7) ENSMUSG00000020430(Pes1) ENSG00000100029(PES1) "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0069110 mus314 mutagen-sensitive 314 http://flybase.net/reports/FBgn0069110.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0037114 Cpr78E Cuticular protein 78E http://flybase.net/reports/FBgn0037114.html FBgn0063114 protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr78E, CG7160, BcDNA:LP06027" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG7160 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0260601 2L1710 http://flybase.net/reports/FBgn0260601.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0031872 ihog interference hedgehog http://flybase.net/reports/FBgn0031872.html protein_coding_gene "0008201=heparin binding, 0097108=hedgehog family protein binding, 0005515=protein binding, 0042803=protein homodimerization activity, 0008158=hedgehog receptor activity" "0045746=negative regulation of Notch signaling pathway, 0008589=regulation of smoothened signaling pathway, 0007224=smoothened signaling pathway, 0035222=wing disc pattern formation, 0001751=compound eye photoreceptor cell differentiation, 0048749=compound eye development, 0035017=cuticle pattern formation, 0045880=positive regulation of smoothened signaling pathway" "0016021=integral component of membrane, 0009986=cell surface" "CT26314, Interference hedgehog, interference Hedgehog, Ihog, CG9211, ihog, iHog, interference hedgehog" "IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013151=Immunoglobulin" CG9211 16-Dec-15 2015_12 ENSDARG00000061328(cdon) ENSXETG00000000029(CDON) "ENSMUSG00000038119(Cdon),ENSMUSG00000022687(Boc)" "ENSG00000064309(CDON),ENSG00000144857(BOC)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,rescuable maternal effect,some die during P-stage" "denticle belt,maternal effect,wing,chaeta,supernumerary" FBgn0039366 CG17198 http://flybase.net/reports/FBgn0039366.html protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0008270=zinc ion binding" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17198 16-Dec-15 2015_12 YOL003C(PFA4) WBGene00008606(dhhc-1) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) viable FBgn0259167 CG42272 http://flybase.net/reports/FBgn0259167.html "FBgn0052415, FBgn0052416" protein_coding_gene "CG32415, CG32416" CG42272 16-Dec-15 2015_12 "YPR157W(),YGR141W(VPS62)" DRSC22502 IE -2.240561608 -2.319809199 -1.697546794 -1.911550338 0.007429552 0.77011531 FBgn0020390 P-25 P-25 http://flybase.net/reports/FBgn0020390.html gene 0007629=flight behavior 16-Dec-15 2015_12 FBgn0037908 dpr5 defective proboscis extension response 5 http://flybase.net/reports/FBgn0037908.html protein_coding_gene 0007606=sensory perception of chemical stimulus "CT16895, CG5308, dpr5, Dpr-5, Dpr5" "IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013106=Immunoglobulin V-set domain" CG5308 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) "ENSG00000105767(CADM4),ENSG00000182985(CADM1),ENSG00000175161(CADM2),ENSG00000162706(CADM3)" viable FBgn0051091 CG31091 http://flybase.net/reports/FBgn0051091.html FBgn0039388 protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process CG5990 "IPR006693=Partial AB-hydrolase lipase domain, IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold" CG31091 16-Dec-15 2015_12 YKL140W(TGL1) ENSXETG00000009273(lipA) viable FBgn0027632 ms(1)287 ms(1)287 http://flybase.net/reports/FBgn0027632.html gene 16-Dec-15 2015_12 male sterile FBgn0038150 yellow-e3 yellow-e3 http://flybase.net/reports/FBgn0038150.html protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "CG17045, Yellow-d4, e3, yel-e3" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG17045 16-Dec-15 2015_12 viable FBgn0032499 Uvrag UV-resistance associated gene http://flybase.net/reports/FBgn0032499.html protein_coding_gene "0045746=negative regulation of Notch signaling pathway, 0000046=autophagic vacuole fusion, 0048803=imaginal disc-derived male genitalia morphogenesis, 0016322=neuron remodeling, 0010508=positive regulation of autophagy, 0048260=positive regulation of receptor-mediated endocytosis, 0008285=negative regulation of cell proliferation" "UV radiation resistance associated gene, Vps38, CG6116, UV radiation resistance associated, uvrag, UVRAG" IPR018791=UV radiation resistance protein/autophagy-related protein 14 CG6116 16-Dec-15 2015_12 ENSXETG00000015063(UVRAG) ENSG00000198382(UVRAG) "lethal - all die before end of P-stage,increased cell number,somatic clone,viable,lethal - all die before end of larval stage,male limited,recessive,some die during larval stage,eye color defective" "follicle cell,somatic clone,male genitalia,embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditional,eye,major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16" FBgn0250872 pio::tor http://flybase.net/reports/FBgn0250872.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0267206 CR45646 http://flybase.net/reports/FBgn0267206.html non_protein_coding_gene CR45646 16-Dec-15 2015_12 FBgn0065149 l(3)SH075 lethal (3) SH075 http://flybase.net/reports/FBgn0065149.html gene l(2)SH3 075 16-Dec-15 2015_12 "lethal,recessive" FBgn0060306 l(3)S148316b lethal (3) S148316b http://flybase.net/reports/FBgn0060306.html gene 1483/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0085816 CR41606 http://flybase.net/reports/FBgn0085816.html FBan0041606 rRNA_gene CR41606 16-Dec-15 2015_12 FBgn0036184 PCID2 PCI domain-containing protein 2 http://flybase.net/reports/FBgn0036184.html protein_coding_gene 0047499=calcium-independent phospholipase A2 activity "0005737=cytoplasm, 0005829=cytosol, 0005844=polysome" "Drosophila melanogaster PCID2, dmPCID2, CG7351" "IPR013143=PCI/PINT associated module, IPR021184=Tumour necrosis factor, conserved site, IPR000717=Proteasome component (PCI) domain" CG7351 16-Dec-15 2015_12 ENSDARG00000013802(pcid2) YJR084W(CSN12) WBGene00016171(C27F2.10) ENSXETG00000001931(BC080509.1) ENSMUSG00000038542(Pcid2) ENSG00000126226(PCID2) "viable,female fertile" DRSC10822 K 1.446624442 0.680635261 0.014607143 0.115223299 -1.718500321 0.10188268 FBgn0259173 corn cornetto http://flybase.net/reports/FBgn0259173.html "FBgn0028383, FBgn0035745, FBgn0052386, FBgn0052390" protein_coding_gene "0008017=microtubule binding, 0005515=protein binding" 0045921=positive regulation of exocytosis "0045177=apical part of cell, 0043234=protein complex, 0005938=cell cortex, 0005737=cytoplasm" "CG32386, CG8621, Cornetto, CG42278, CG32390, unnamed" CG42278 16-Dec-15 2015_12 FBgn0031696 Bub1 Bub1 homologue http://flybase.net/reports/FBgn0031696.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0007094=mitotic spindle assembly checkpoint" 0005813=centrosome "CG14030, BubRI, CG14030/Bub1, BUB1-like, BUB1, BubR1, bub1" "IPR015661=Mitotic spindle checkpoint protein Bub1/Mad3, IPR017441=Protein kinase, ATP binding site, IPR013212=Mad3/Bub1 homology region 1, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG14030 16-Dec-15 2015_12 ENSDARG00000041361(ttk) YGR188C(BUB1) WBGene00000275(bub-1) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0020059 E(wa)705 E(wa)705 http://flybase.net/reports/FBgn0020059.html gene E705 16-Dec-15 2015_12 eye color defective pigment cell FBgn0000695 fltA flight defective A http://flybase.net/reports/FBgn0000695.html gene 16-Dec-15 2015_12 flight defective FBgn0036070 CG8072 http://flybase.net/reports/FBgn0036070.html protein_coding_gene 0005576=extracellular region "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG8072 16-Dec-15 2015_12 "WBGene00016821(scl-26),WBGene00011841(scl-25),WBGene00008575(scl-24),WBGene00022638(scl-27)" viable DRSC10960 K 0.040563154 -0.387554011 -0.392544461 0.47869815 1.569390645 1.26807552 FBgn0014254 l(2)DB1 lethal (2) DB1 http://flybase.net/reports/FBgn0014254.html gene DB1 16-Dec-15 2015_12 "lethal,recessive" FBgn0030559 CG13404 http://flybase.net/reports/FBgn0030559.html protein_coding_gene IPR019319=Protein of unknown function DUF2368 CG13404 16-Dec-15 2015_12 WBGene00044323(tag-281) ENSXETG00000000585(C9orf46) ENSMUSG00000016495(5033414D02Rik) ENSG00000107020(C9orf46) viable FBgn0036441 CG13476 http://flybase.net/reports/FBgn0036441.html protein_coding_gene CG13476 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0065942 l(2)SH0114 lethal (2) SH0114 http://flybase.net/reports/FBgn0065942.html gene l(2)SH2 0114 16-Dec-15 2015_12 "lethal,recessive" FBgn0040911 CG12683 http://flybase.net/reports/FBgn0040911.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038632 CG14301 http://flybase.net/reports/FBgn0038632.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14301 16-Dec-15 2015_12 "viable,fertile" FBgn0039674 CG1907 http://flybase.net/reports/FBgn0039674.html protein_coding_gene "0022857=transmembrane transporter activity, 0015367=oxoglutarate:malate antiporter activity" "0015742=alpha-ketoglutarate transport, 0006839=mitochondrial transport, 0015743=malate transport" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane, 0005811=lipid particle, 0005739=mitochondrion" CG 1907 "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG1907 16-Dec-15 2015_12 ENSDARG00000035741(zgc:86898) WBGene00015186(misc-1) ENSXETG00000014955(Q566L1_XENTR) ENSMUSG00000014606(Slc25a11) ENSG00000108528(SLC25A11) "viable,planar polarity defective" FBgn0021845 l(2)k14810 lethal (2) k14810 http://flybase.net/reports/FBgn0021845.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0085549 CG40973 http://flybase.net/reports/FBgn0085549.html FBan0040973 protein_coding_gene 16-Dec-15 2015_12 FBgn0264903 CG44094 http://flybase.net/reports/FBgn0264903.html protein_coding_gene CG44094 16-Dec-15 2015_12 FBgn0032281 CG17107 http://flybase.net/reports/FBgn0032281.html protein_coding_gene CG17107 16-Dec-15 2015_12 viable DRSC02575 K -0.330602205 0.733076153 -0.068607194 0.066521052 -1.651889198 -0.475095495 FBgn0026176 SkpB SKP1-related B http://flybase.net/reports/FBgn0026176.html FBgn0033684 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "CG8881, skpB, Skp, dskpB, SkpB" "IPR011333=POZ domain, IPR016897=S-phase kinase-associated protein 1, IPR016072=SKP1 component, dimerisation, IPR001232=S-phase kinase-associated protein 1-like, IPR016073=SKP1 component, POZ domain" CG8881 16-Dec-15 2015_12 YDR328C(SKP1) "WBGene00004807(skr-1),WBGene00004808(skr-2)" "viable,visible,planar polarity defective" mesothoracic tergum FBgn0003928 snRNA:U3:95C small nuclear RNA U3 at 95C http://flybase.net/reports/FBgn0003928.html FBgn0003925 snRNA_gene "0000398=mRNA splicing, via spliceosome" "snRNA3, small nuclear RNA U3, snRNA2, snRNA[[2]], U3snRNA, K7, snRNA:U3, U3snRNA95C" 16-Dec-15 2015_12 FBgn0085776 CR40855 http://flybase.net/reports/FBgn0085776.html FBan0040855 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0005265 l(3)SG85 lethal (3) SG85 http://flybase.net/reports/FBgn0005265.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0265497 CR44366 http://flybase.net/reports/FBgn0265497.html non_protein_coding_gene CR44366 16-Dec-15 2015_12 FBgn0004797 mdy midway http://flybase.net/reports/FBgn0004797.html "FBgn0032608, FBgn0032610, FBgn0032611, FBgn0051991" protein_coding_gene "0004144=diacylglycerol O-acyltransferase activity, 0004772=sterol O-acyltransferase activity" "0048477=oogenesis, 0019432=triglyceride biosynthetic process, 0010888=negative regulation of lipid storage, 0035220=wing disc development, 0045477=regulation of nurse cell apoptotic process" "CG13273, diacylglycerol acyltransferase, DGAT1, CG31991, Midway, DGAT, CT39962, CG17937, mdcds_3562, Dgat1, CG17938, Mdy" "IPR027251=Diacylglycerol O-acyltransferase 1, IPR004299=Membrane bound O-acyl transferase, MBOAT, IPR014371=Sterol O-acyltransferase, ACAT/DAG/ARE types" CG31991 16-Dec-15 2015_12 "ENSDARG00000054914(dgat1b),ENSDARG00000031465(dgat1a)" "YNR019W(ARE2),YCR048W(ARE1)" WBGene00010408(mboa-2) ENSXETG00000001450(DGAT1) ENSMUSG00000022555(Dgat1) "ENSG00000215711,ENSG00000185000(DGAT1)" "female sterile,recessive,viable" "salivary gland,lipid particle | ectopicppl.PP,lipid particle | ectopic48Y,nurse cell & nucleus,egg chamber,nurse cell & nuclear membrane" FBgn0001858 l(1)TW3 lethal (1) TW3 http://flybase.net/reports/FBgn0001858.html gene 16-Dec-15 2015_12 "female fertile,chemical sensitive,lethal - all die before end of pupal stage,cold sensitive,some die during pupal stage" FBgn0024994 Csat Csat http://flybase.net/reports/FBgn0024994.html FBgn0015871 protein_coding_gene "0005461=UDP-glucuronic acid transmembrane transporter activity, 0005351=sugar:proton symporter activity, 0005456=CMP-N-acetylneuraminate transmembrane transporter activity, 0005459=UDP-galactose transmembrane transporter activity, 0005464=UDP-xylose transmembrane transporter activity, 0005463=UDP-N-acetylgalactosamine transmembrane transporter activity" "0015789=UDP-N-acetylgalactosamine transport, 0015757=galactose transport, 0015785=UDP-galactose transport, 0015782=CMP-N-acetylneuraminate transport" "0016021=integral component of membrane, 0000139=Golgi membrane, 0005797=Golgi medial cisterna" "DmNST, anon-3Bb, dNST-1, unnamed, UDP-Gal/UDP-GalNAc, CSAT, ugt, dNST-2, EG:100G10.5, CG2675, DmUGT, D.melanogaster nucleotide sugar transporter" "IPR004689=UDP-galactose transporter, IPR007271=Nucleotide-sugar transporter, IPR021189=UDP/CMP-sugar transporter" CG2675 16-Dec-15 2015_12 ENSDARG00000058990(LOC555288) WBGene00015404(C03H5.2) "ENSXETG00000026892(slc35a3),ENSXETG00000013193()" ENSMUSG00000031156(Slc35a2) ENSG00000102100(SLC35A2) "viable,fertile" FBgn0277421 l(3)psg16 http://flybase.net/reports/FBgn0277421.html gene psg16 16-Dec-15 2015_12 FBgn0011252 ms(3)04202 ms(3)04202 http://flybase.net/reports/FBgn0011252.html gene ms(3)65E 16-Dec-15 2015_12 "male sterile,recessive" FBgn0265488 BG01340 http://flybase.net/reports/FBgn0265488.html gene 16-Dec-15 2015_12 FBgn0085327 CG34298 http://flybase.net/reports/FBgn0085327.html protein_coding_gene CG34298 16-Dec-15 2015_12 FBgn0033536 CG16942 http://flybase.net/reports/FBgn0033536.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033353 CG13749 http://flybase.net/reports/FBgn0033353.html protein_coding_gene CG13749 16-Dec-15 2015_12 viable FBgn0030833 CG8915 http://flybase.net/reports/FBgn0030833.html protein_coding_gene "0004386=helicase activity, 0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "helicasa, cg8915" "IPR011709=Domain of unknown function DUF1605, IPR007502=Helicase-associated domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001374=R3H domain, IPR031083=ATP-dependent RNA helicase YTHDC2-related, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG8915 16-Dec-15 2015_12 WBGene00009922(F52B5.3) viable FBgn0035756 unc-13-4A unc-13-4A http://flybase.net/reports/FBgn0035756.html "FBgn0035757, FBgn0035758, FBgn0035759, FBgn0052381" protein_coding_gene "0007269=neurotransmitter secretion, 0016082=synaptic vesicle priming" 0008021=synaptic vesicle "CG14833, CG14831, CG14832, CG32381, CG8608, dunc-13-4A" "IPR019558=Mammalian uncoordinated homology 13, subgroup, domain 2, IPR000008=C2 domain, IPR014772=Mammalian uncoordinated homology 13, domain 2, IPR014770=Munc13 homology 1" CG32381 16-Dec-15 2015_12 "ENSDARG00000061829(si:dkey-110c1.7),ENSDARG00000017391" WBGene00018837(F54G2.1) ENSXETG00000021585(BAIAP3) ENSMUSG00000047507 ENSG00000007516(BAIAP3) viable FBgn0028215 l(3)S008840 lethal (3) S008840 http://flybase.net/reports/FBgn0028215.html gene 0088/40 16-Dec-15 2015_12 "lethal,recessive" FBgn0261580 CG42690 http://flybase.net/reports/FBgn0261580.html protein_coding_gene CG42690 16-Dec-15 2015_12 FBgn0022665 Dep4 Dep4 http://flybase.net/reports/FBgn0022665.html gene 0003677=DNA binding 0005634=nucleus DEP4 16-Dec-15 2015_12 FBgn0029002 miple2 midkine and pleiotrophin 2 http://flybase.net/reports/FBgn0029002.html FBgn0035123 protein_coding_gene "0008201=heparin binding, 0008083=growth factor activity" 0008340=determination of adult lifespan 0005576=extracellular region "miple2, CG18321, Miple2" "IPR020090=Pleiotrophin/Midkine, C-terminal domain" CG18321 16-Dec-15 2015_12 "viable,fertile" FBgn0060765 l(3)S062914b lethal (3) S062914b http://flybase.net/reports/FBgn0060765.html gene 0629/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033348 Spt Spitting Image http://flybase.net/reports/FBgn0033348.html protein_coding_gene 0007349=cellularization "0016020=membrane, 0032154=cleavage furrow, 0031941=filamentous actin, 0005737=cytoplasm" "spt, CG8247" IPR008837=Serendipity locus alpha CG8247 16-Dec-15 2015_12 viable DRSC07123 I 3.438918057 0.555937269 0.425841963 -0.631712712 -0.602673887 -0.501780348 FBgn0030884 CG6847 http://flybase.net/reports/FBgn0030884.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold" CG6847 16-Dec-15 2015_12 viable FBgn0032136 Apoltp Apolipoprotein lipid transfer particle http://flybase.net/reports/FBgn0032136.html protein_coding_gene "0008289=lipid binding, 0070325=lipoprotein particle receptor binding, 0005319=lipid transporter activity" "0034196=acylglycerol transport, 0032370=positive regulation of lipid transport, 0015918=sterol transport" "0045178=basal part of cell, 0005875=microtubule associated complex, 0005615=extracellular space, 0005886=plasma membrane" "ApoLTPII, CG15828, ApoLTPI, LTP, CT39214, Lipid Transfer Particle, apoltp, apoLTP" "IPR015818=Vitellinogen, open beta-sheet, subdomain 2, IPR001747=Lipid transport protein, N-terminal, IPR015819=Lipid transport protein, beta-sheet shell, IPR011030=Vitellinogen, superhelical, IPR015816=Vitellinogen, beta-sheet N-terminal, IPR014853=Uncharacterised domain, cysteine-rich, IPR001846=von Willebrand factor, type D domain, IPR009454=Lipid transport, open beta-sheet, IPR015255=Vitellinogen, open beta-sheet, IPR015817=Vitellinogen, open beta-sheet, subdomain 1" CG15828 16-Dec-15 2015_12 ENSG00000084674(APOB) "embryonic/larval midgut | third instar larval stage,embryonic/larval fat body | third instar larval stage,wing disc | third instar larval stage,embryonic/larval brain | third instar larval stage,embryonic/larval hemolymph | third instar larval stage" FBgn0265058 CR44169 http://flybase.net/reports/FBgn0265058.html non_protein_coding_gene CR44169 16-Dec-15 2015_12 FBgn0036345 CG17300 http://flybase.net/reports/FBgn0036345.html protein_coding_gene "0046933=proton-transporting ATP synthase activity, rotational mechanism" 0015986=ATP synthesis coupled proton transport "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "IPR013837=ATPase, F0 complex, B chain/subunit B" CG17300 16-Dec-15 2015_12 YPL078C(ATP4) viable FBgn0000230 bsp brown spots http://flybase.net/reports/FBgn0000230.html gene 16-Dec-15 2015_12 "visible,female limited,recessive,viable" cuticle FBgn0004678 E(lz) Enhancer of lozenge http://flybase.net/reports/FBgn0004678.html gene 16-Dec-15 2015_12 FBgn0259586 B0258 http://flybase.net/reports/FBgn0259586.html gene 16-Dec-15 2015_12 visible wing FBgn0015971 l(2)CA3 lethal (2) CA3 http://flybase.net/reports/FBgn0015971.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003431 slrp slow receptor potential http://flybase.net/reports/FBgn0003431.html gene "0009612=response to mechanical stimulus, 0007629=flight behavior" "hypoD, hypoactive-D" 16-Dec-15 2015_12 neurophysiology defective FBgn0002679 mat(2)syn-G maternal effect syncytial blastoderm arrest G http://flybase.net/reports/FBgn0002679.html gene "0007279=pole cell formation, 0007349=cellularization" mat(2)synQF75 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0036356 CG10222 http://flybase.net/reports/FBgn0036356.html protein_coding_gene 0022008=neurogenesis "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR004130=GPN-loop GTPase, IPR030231=GPN-loop GTPase 2" CG10222 16-Dec-15 2015_12 "ENSDARG00000069810,ENSDARG00000069820(gpn2)" YOR262W() WBGene00015029(B0207.6) ENSXETG00000020692(BC091618.1) ENSMUSG00000028848(Gpn2) ENSG00000142751(GPN2) "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0028094 l(3)S075101 lethal (3) S075101 http://flybase.net/reports/FBgn0028094.html gene 0751/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0086695 hd humpty dumpty http://flybase.net/reports/FBgn0086695.html "FBgn0037316, FBgn0001008, FBgn0025926, FBgn0013578" protein_coding_gene "0007307=eggshell chorion gene amplification, 0033260=nuclear DNA replication, 0008283=cell proliferation" 0005634=nucleus "female sterile(3)272-9, fs(3)272, fs(3)272-9, l(3)82Fk, humpty dumpty, lethal (3) 82Ff, lethal (3) 82Fk, CG2669, l(3)82Ff" IPR024861=Donson CG2669 16-Dec-15 2015_12 WBGene00016074(C24H12.5) ENSXETG00000027925(donson) ENSMUSG00000022960(Donson) ENSG00000159147(DONSON) FBgn0261277 rtv retroactive http://flybase.net/reports/FBgn0261277.html "FBgn0005400, FBgn0001487, FBgn0003294, FBgn0030275" protein_coding_gene "0006031=chitin biosynthetic process, 0007424=open tracheal system development, 0035152=regulation of tube architecture, open tracheal system, 0008362=chitin-based embryonic cuticle biosynthetic process, 0035158=regulation of tube diameter, open tracheal system" "L1, l(1)G13, l(1)10Ag, l(1)L1, 1, CG1397" CG1397 16-Dec-15 2015_12 FBgn0030551 CG11674 http://flybase.net/reports/FBgn0030551.html protein_coding_gene 0004004=ATP-dependent RNA helicase activity "0000398=mRNA splicing, via spliceosome" 0005681=spliceosomal complex IPR006149=EB domain CG11674 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0265089 eIF4E-3 eukaryotic translation initiation factor 4E-3 http://flybase.net/reports/FBgn0265089.html "FBgn0024529, FBgn0035860, FBgn0044644" protein_coding_gene "0031370=eukaryotic initiation factor 4G binding, 0003743=translation initiation factor activity, 0000340=RNA 7-methylguanosine cap binding, 0000339=RNA cap binding, 0005515=protein binding" "0007283=spermatogenesis, 0048515=spermatid differentiation, 0007112=male meiosis cytokinesis, 0045727=positive regulation of translation, 0048137=spermatocyte division, 0007060=male meiosis chromosome segregation, 0006413=translational initiation, 0010032=meiotic chromosome condensation" "0016281=eukaryotic translation initiation factor 4F complex, 0005737=cytoplasm" "eIF4E, CG8023, lethal (3) L0139, anon-WO0140519.227, eIF4E-3, elF4E-3, l(3)L0139, l(3)0139" "IPR019770=Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, IPR001040=Translation Initiation factor eIF- 4e, IPR023398=Translation Initiation factor eIF- 4e-like" CG8023 16-Dec-15 2015_12 "ENSDARG00000013274(zgc:101581),ENSDARG00000012274(zgc:110154),ENSDARG00000014565(eif4e1b)" YOL139C(CDC33) WBGene00002061(ife-3) ENSMUSG00000028156(Eif4e) "ENSG00000151247(EIF4E),ENSG00000175766(EIF4E1B)" "lethal,recessive,male sterile,female fertile,meiotic cell cycle defective,male,viable" "sperm individualization complexBSC732),spermatozoon,Nebenkern derivative,pre-elongation spermatid,elongation stage spermatid,seminal vesicle" FBgn0266905 CR45365 http://flybase.net/reports/FBgn0266905.html non_protein_coding_gene CR45365 16-Dec-15 2015_12 FBgn0267295 CR45731 http://flybase.net/reports/FBgn0267295.html non_protein_coding_gene lincRNA.624 CR45731 16-Dec-15 2015_12 FBgn0046638 anon-38D.7 anon-38D.7 http://flybase.net/reports/FBgn0046638.html gene 38D.7 16-Dec-15 2015_12 FBgn0050074 Obp50d Odorant-binding protein 50d http://flybase.net/reports/FBgn0050074.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG30074, DmelObp50d" CG30074 16-Dec-15 2015_12 viable FBgn0040231 dac::Ggal\Dach2 Dach2 http://flybase.net/reports/FBgn0040231.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0005150 l(2)G80 lethal (2) G80 http://flybase.net/reports/FBgn0005150.html gene 16-Dec-15 2015_12 lethal FBgn0024254 aim aimless http://flybase.net/reports/FBgn0024254.html gene 0007017=microtubule-based process 16-Dec-15 2015_12 FBgn0261719 EP1174 http://flybase.net/reports/FBgn0261719.html gene 16-Dec-15 2015_12 chemical resistant FBgn0041189 SSP6107 SSP6107 http://flybase.net/reports/FBgn0041189.html gene 16-Dec-15 2015_12 FBgn0036389 ssp2 short spindle 2 http://flybase.net/reports/FBgn0036389.html protein_coding_gene "0000022=mitotic spindle elongation, 2001020=regulation of response to DNA damage stimulus, 0000226=microtubule cytoskeleton organization" 0005813=centrosome "Ssp2, CG9028, short spindle, sentin" CG9028 16-Dec-15 2015_12 "viable,stress response defective" FBgn0261593 RpS10b Ribosomal protein S10b http://flybase.net/reports/FBgn0261593.html "FBgn0031035, FBgn0002591" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005634=nucleus, 0022627=cytosolic small ribosomal subunit, 0005875=microtubule associated complex, 0005840=ribosome" "M(1)36f, S10b, M[[n]], CT33819, i73, GM19176, M(1)n, i3, M(1)18C, Minute (1) 18C, Rp S10 b, l(1)carot13, Minute-n, CG14206" "IPR005326=Plectin/S10, N-terminal" CG14206 16-Dec-15 2015_12 ENSDARG00000034897(rps10) "YOR293W(RPS10A),YMR230W(RPS10B)" WBGene00004479(rps-10) ENSXETG00000015129(rps10) "ENSMUSG00000052146(Rps10),ENSMUSG00000063427" "ENSG00000101278,ENSG00000124614(RPS10),ENSG00000215464" DRSC19561 I 0.169516399 -1.649055259 -0.174126838 0.116714775 0.01645748 0.869459086 FBgn0265150 CR44219 http://flybase.net/reports/FBgn0265150.html non_protein_coding_gene CR44219 16-Dec-15 2015_12 FBgn0051420 CR31420 http://flybase.net/reports/FBgn0051420.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0060888 l(3)S044631 lethal (3) S044631 http://flybase.net/reports/FBgn0060888.html gene 0446/31 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267061 CR45505 http://flybase.net/reports/FBgn0267061.html non_protein_coding_gene CR45505 16-Dec-15 2015_12 FBgn0037956 CG6959 http://flybase.net/reports/FBgn0037956.html protein_coding_gene "6959, CT21563, connectin-like" "IPR001611=Leucine-rich repeat, IPR000483=Cysteine-rich flanking region, C-terminal" CG6959 16-Dec-15 2015_12 "ENSDARG00000040216(tpbgl),ENSDARG00000061144,ENSDARG00000037186(sc:d0347),ENSDARG00000054575" WBGene00007261(C02C6.3) ENSXETG00000018660() ENSMUSG00000035274(Tpbg) ENSG00000146242(TPBG) FBgn0032921 Mpp6 M-phase phosphoprotein 6 http://flybase.net/reports/FBgn0032921.html "FBgn0021817, FBgn0063007" protein_coding_gene 0022008=neurogenesis "mpp6, dMPP6, MPP6, Mpps, l(2)k16403, BcDNA:RE45276, CG9250" IPR019324=M-phase phosphoprotein 6 CG9250 16-Dec-15 2015_12 ENSDARG00000045554(LOC100331527) ENSXETG00000025878(mphosph6) ENSMUSG00000031843(Mphosph6) ENSG00000135698(MPHOSPH6) "lethal,recessive,wild-type,viable,visible,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,ganglion mother cell" FBgn0259323 C719.1 http://flybase.net/reports/FBgn0259323.html gene 16-Dec-15 2015_12 visible wing FBgn0037997 CG14742 http://flybase.net/reports/FBgn0037997.html protein_coding_gene DMG8-chr3R.14.009 CG14742 16-Dec-15 2015_12 FBgn0016772 anon-70Da anon-70Da http://flybase.net/reports/FBgn0016772.html gene "beta transcript, beta" 16-Dec-15 2015_12 FBgn0013311 P\T P element transposase http://flybase.net/reports/FBgn0013311.html transposable_element_gene "87-kDa transposase, dmTRP, 66-kDa repressor, P-element\T, unnamed, P transposase, A24786" 16-Dec-15 2015_12 " embryonic stage , embryonic stage -- adult stage " adult stage && oogenesis stage " ovary

, unfertilized egg

" "non-suppressor of variegation,suppressor of variegation,partially,wild-type,fertile,recessive,reduced,sterile,lethal" FBgn0001305 Kf2 Kynurenine formamidase 2 http://flybase.net/reports/FBgn0001305.html gene 0004061=arylformamidase activity 16-Dec-15 2015_12 FBgn0036036 CG14174 http://flybase.net/reports/FBgn0036036.html protein_coding_gene 0022008=neurogenesis IPR027951=Domain of unknown function DUF4477 CG14174 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible,body color defective" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000125 Ars-region3 Autonomous replicating sequence region 3 http://flybase.net/reports/FBgn0000125.html region "PHc700, Ars sequence 3, Ars3" 16-Dec-15 2015_12 FBgn0003628 Su(var)319 Suppressor of variegation 319 http://flybase.net/reports/FBgn0003628.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable" FBgn0001068 Fs(3)Ton Female sterile (3) Tonuz http://flybase.net/reports/FBgn0001068.html gene "Fs(3)Sz23, Fs(3)Tonuz, Ton" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0065781 l(2)SH0443 lethal (2) SH0443 http://flybase.net/reports/FBgn0065781.html gene l(2)SH2 0443 16-Dec-15 2015_12 "lethal,recessive" FBgn0011149 l(1)Q225 lethal (1) Q225 http://flybase.net/reports/FBgn0011149.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0051698 CG31698 http://flybase.net/reports/FBgn0051698.html FBgn0063131 protein_coding_gene BcDNA:LP02725 CG31698 16-Dec-15 2015_12 viable FBgn0051735 CG31735 http://flybase.net/reports/FBgn0051735.html FBgn0063313 protein_coding_gene 0032027=myosin light chain binding BcDNA:AT20140 "IPR000048=IQ motif, EF-hand binding site" CG31735 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0259476 EP-E http://flybase.net/reports/FBgn0259476.html gene 16-Dec-15 2015_12 visible wing FBgn0041841 E(Sev-CycE)E44 E(Sev-CycE)E44 http://flybase.net/reports/FBgn0041841.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025126 su(RpII140Z36)S20 su(RpII140Z36)S20 http://flybase.net/reports/FBgn0025126.html gene Z36[S20] 16-Dec-15 2015_12 FBgn0263501 CR43490 http://flybase.net/reports/FBgn0263501.html non_protein_coding_gene CR43490 16-Dec-15 2015_12 FBgn0065189 l(2)SH2339 lethal (2) SH2339 http://flybase.net/reports/FBgn0065189.html gene l(2)SH2 2339 16-Dec-15 2015_12 "lethal,recessive" FBgn0085567 CG41239 http://flybase.net/reports/FBgn0085567.html FBan0041239 protein_coding_gene 16-Dec-15 2015_12 FBgn0001218 Hsc70-3 Heat shock 70-kDa protein cognate 3 http://flybase.net/reports/FBgn0001218.html "FBgn0027308, FBgn0027310, FBgn0028286, FBgn0028330, FBgn0029049, FBgn0030335, FBgn0040174, FBgn0044787" protein_coding_gene 0016887=ATPase activity "0030431=sleep, 0009408=response to heat, 0051298=centrosome duplication, 0016246=RNA interference" "0005783=endoplasmic reticulum, 0005615=extracellular space, 0005875=microtubule associated complex, 0012505=endomembrane system, 0005811=lipid particle" "Heat shock protein cognate 70-3, heat-shock cognate 70-3, Hsc-70-3, Hsc70, l(1)G0466, HSC70-3, HSC70, hsc3, l(1)G0292, anon-WO0138581.7, immunoglobulin binding protein, HSP7C_DROME, heat shock cognate protein 3, hsc70-3, Grp78, heat shock protein cognate 72, bip, hsc70, HSC-70, dmHsc72, BiP, Hsc-3, l(1)G0111, A4V4C4_DROME, CG4147, Bip, Hsc3, hsc72, l(1)G0102, Hsp-c3, GRP78, CG1579, HSC3, Hsc3p, dBiP, dhsc70, Heat shock protein cognate 3, l(1)G0341, l(1)G0407, Heat shock 70-kDa protein cognate 3" "IPR013126=Heat shock protein 70 family, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site, IPR029047=Heat shock protein 70kD, peptide-binding domain" CG4147 16-Dec-15 2015_12 ENSDARG00000004665(hspa5) YJL034W(KAR2) "WBGene00002007(hsp-3),WBGene00002008(hsp-4)" ENSXETG00000016838(HSPA5) ENSMUSG00000026864(Hspa5) ENSG00000044574(HSPA5) "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage,behavior defective,neuroanatomy defective,dominant" "rhabdomere R7,pupa,third instar larva,adult antennal lobe projection neuron,eye,ommatidium" DRSC20253 K 1.240152423 0.540441277 1.029897444 -1.350018397 2.67489083 3.744226606 FBgn0266976 CR45427 http://flybase.net/reports/FBgn0266976.html non_protein_coding_gene CR45427 16-Dec-15 2015_12 FBgn0003282 rsc reduplicated sex combs http://flybase.net/reports/FBgn0003282.html gene 16-Dec-15 2015_12 "male fertile,viable,male,poor,lethal,female,visible" "wing,leg" FBgn0000601 E(var)100C-F Enhancer of variegation 100 http://flybase.net/reports/FBgn0000601.html gene "E(var)100CF, E(var)100" 16-Dec-15 2015_12 "lethal,recessive,enhancer of variegation,dominant" FBgn0027642 l(3)SCEI-1 lethal (3) SCEI-1 http://flybase.net/reports/FBgn0027642.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0014023 mRpL47 mitochondrial ribosomal protein L47 http://flybase.net/reports/FBgn0014023.html FBgn0063700 protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0032543=mitochondrial translation" 0005762=mitochondrial large ribosomal subunit "MRP-L47, Rlc1, mRpL47, CG9378, BcDNA:AT29239" "IPR010729=Ribosomal protein L47, mitochondrial" CG9378 16-Dec-15 2015_12 WBGene00015092(B0261.4) ENSMUSG00000037531 ENSG00000136522(MRPL47) "viable,visible,body color defective,fertile" "trichogen cell,mesothoracic tergum" FBgn0040722 CG14349 http://flybase.net/reports/FBgn0040722.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019938 RpI1 RNA polymerase I subunit http://flybase.net/reports/FBgn0019938.html protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding, 0008270=zinc ion binding" 0006360=transcription from RNA polymerase I promoter "0005634=nucleus, 0005736=DNA-directed RNA polymerase I complex" "RNA polymerase I, CG10122, DmRPA1, RPA1, 153129_at" "IPR000722=RNA polymerase, alpha subunit, IPR007080=RNA polymerase Rpb1, domain 1, IPR015699=DNA-directed RNA pol I, largest subunit, IPR007081=RNA polymerase Rpb1, domain 5, IPR007066=RNA polymerase Rpb1, domain 3, IPR007083=RNA polymerase Rpb1, domain 4, IPR006592=RNA polymerase, N-terminal" CG10122 16-Dec-15 2015_12 YOR341W(RPA190) WBGene00012999(Y48E1A.1) ENSXETG00000001952(POLR1A) ENSMUSG00000049553(Polr1a) ENSG00000068654(POLR1A) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0044410 Scim17 Sensitized chromosome inheritance modifier 17 http://flybase.net/reports/FBgn0044410.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0267805 CR46130 http://flybase.net/reports/FBgn0267805.html non_protein_coding_gene CR46130 16-Dec-15 2015_12 FBgn0000289 cg combgap http://flybase.net/reports/FBgn0000289.html "FBgn0010639, FBgn0020273, FBgn0033908" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" 0007476=imaginal disc-derived wing morphogenesis 0005634=nucleus "CG8367, comb gap, migraine, l(2)k11504, mig, l(2)07659, Combgap" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG8367 16-Dec-15 2015_12 "viable,neuroanatomy defective,fertile,visible,partially lethal - majority die,lethal,recessive,female sterile,hyperplasia,wild-type,dominant" "Kenyon cell,adult mushroom body,wing vein L4,sex comb,supernumerary,wing vein L5,wing vein L2,wing margin,anterior,ventral thoracic disc,prothoracic tibial transverse row bristle,wing,posterior compartment,anterior compartment,prothoracic tibial preapical bristle,wing vein,macrochaeta,leg,antenna,mesothoracic leg,embryonic/larval salivary gland" FBgn0034515 CG13428 http://flybase.net/reports/FBgn0034515.html protein_coding_gene CG13428 16-Dec-15 2015_12 DRSC06390 E -0.68535721 0.60343617 3.45120395 0.066861111 -0.250193208 -0.372622061 FBgn0259543 GG01179 http://flybase.net/reports/FBgn0259543.html gene 16-Dec-15 2015_12 visible "wing vein,1st posterior cell,leg,tarsal segment,wing" FBgn0031188 CG14613 http://flybase.net/reports/FBgn0031188.html protein_coding_gene "ADP/ATP translocase, CT34370" IPR009688=Domain of unknown function DUF1279 CG14613 16-Dec-15 2015_12 "ENSDARG00000035985(si:ch211-105d11.2),ENSDARG00000070554,ENSDARG00000040186(zgc:113036)" ENSXETG00000014708(C18orf19) FBgn0002165 l(2)Sp9a lethal (2) Sp9a http://flybase.net/reports/FBgn0002165.html gene 16-Dec-15 2015_12 lethal FBgn0011073 l(1)Q26 lethal (1) Q26 http://flybase.net/reports/FBgn0011073.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0267870 CR46158 http://flybase.net/reports/FBgn0267870.html pseudogene_attribute CG12717-related CR46158 16-Dec-15 2015_12 FBgn0040087 p115 p115 http://flybase.net/reports/FBgn0040087.html "FBgn0026701, FBgn0029972, FBgn0040179" protein_coding_gene 0008565=protein transporter activity "0006904=vesicle docking involved in exocytosis, 0007030=Golgi organization, 0051726=regulation of cell cycle, 0006886=intracellular protein transport, 0048280=vesicle fusion with Golgi apparatus" "0005795=Golgi stack, 0000139=Golgi membrane, 0005783=endoplasmic reticulum" "l(1)G0306, dp115, CG1422" "IPR006953=Vesicle tethering protein Uso1/P115-like , head domain, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR006955=Uso1/p115-like vesicle tethering protein, C-terminal, IPR024095=Vesicle tethering protein p115-like, IPR000225=Armadillo" CG1422 16-Dec-15 2015_12 ENSDARG00000019581(uso1) WBGene00010713(uso-1) ENSXETG00000000333(USO1) ENSMUSG00000029407(Uso1) ENSG00000138768(USO1) "partially lethal - majority die,male,female,recessive,viable,body color defective" "Golgi stack,endoplasmic reticulum,mesothoracic tergum" FBgn0260627 d05123 http://flybase.net/reports/FBgn0260627.html gene 16-Dec-15 2015_12 visible wing FBgn0082169 p140S p140S http://flybase.net/reports/FBgn0082169.html gene p140 16-Dec-15 2015_12 FBgn0053307 CG33307 http://flybase.net/reports/FBgn0053307.html "FBgn0028921, FBgn0067630" protein_coding_gene "CG16887, BG:DS00941.11, BcDNA:GH07914, DS00941.11" CG33307 16-Dec-15 2015_12 viable DRSC01349 I 1.440208514 1.826140756 0.634303627 1.426403507 0.193411778 0.179799144 FBgn0003155 psi3 phase angle 3 http://flybase.net/reports/FBgn0003155.html gene "psi-3, psi 3" 16-Dec-15 2015_12 "eclosion rhythm defective,semidominant" FBgn0041132 l(2)44Fj lethal (2) 44Fj http://flybase.net/reports/FBgn0041132.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0027645 l(3)CL-L lethal (3) Cell Lethal Left http://flybase.net/reports/FBgn0027645.html gene CL3L 16-Dec-15 2015_12 lethal FBgn0001502 l(1)10Ce lethal (1) 10Ce http://flybase.net/reports/FBgn0001502.html gene "l(1)L16, l(1)EF476, 16, RA60" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,maternal effect" "egg,germline clone,maternal effect" FBgn0010152 l(3)W lethal (3) W http://flybase.net/reports/FBgn0010152.html gene 16-Dec-15 2015_12 lethal FBgn0032881 CG9319 http://flybase.net/reports/FBgn0032881.html protein_coding_gene 0008111=alpha-methylacyl-CoA racemase activity 0001561=fatty acid alpha-oxidation 0005777=peroxisome 38E.13 "IPR023606=CoA-transferase family III domain, IPR003673=CoA-transferase family III" CG9319 16-Dec-15 2015_12 ENSDARG00000057435(c1qtnf3) "WBGene00016034(C24A3.4),WBGene00014128(ZK892.4)" ENSXETG00000002559(Q68EP6_XENTR) ENSMUSG00000022244(Amacr) ENSG00000082196(C1QTNF3) FBgn0044057 GTD74-77.3 GTD74-77.3 http://flybase.net/reports/FBgn0044057.html gene 16-Dec-15 2015_12 viable FBgn0265879 CR44668 http://flybase.net/reports/FBgn0265879.html non_protein_coding_gene lincRNA.594 CR44668 16-Dec-15 2015_12 FBgn0266955 CR45406 http://flybase.net/reports/FBgn0266955.html non_protein_coding_gene CR45406 16-Dec-15 2015_12 FBgn0033988 pcs parcas http://flybase.net/reports/FBgn0033988.html protein_coding_gene "0017124=SH3 domain binding, 0004860=protein kinase inhibitor activity" "0007301=female germline ring canal formation, 0007498=mesoderm development, 0007517=muscle organ development, 0009952=anterior/posterior pattern specification, 0042694=muscle cell fate specification, 0061099=negative regulation of protein tyrosine kinase activity, 0048644=muscle organ morphogenesis" "0005886=plasma membrane, 0005737=cytoplasm" "poirot, prt, CG7761" IPR007940=SH3-binding 5 CG7761 16-Dec-15 2015_12 "ENSDARG00000019160(sh3bp5la),ENSDARG00000007136(si:ch211-225n7.1)" WBGene00019365(K03E6.7) ENSXETG00000012549(Q6P4N3_XENTR) ENSMUSG00000013646(Sh3bp5l) ENSG00000175137(SH3BP5L) "viable,grandchildless,cold sensitive" "germline cell,embryonic abdomen,embryonic/first instar larval cuticle,embryonic head,visceral mesoderm,maternal effect,cardiogenic mesoderm,muscle founder cell,presumptive embryonic/larval muscle system,embryonic segment,somatic muscle" FBgn0065890 l(2)SH0220 lethal (2) SH0220 http://flybase.net/reports/FBgn0065890.html gene l(2)SH2 0220 16-Dec-15 2015_12 "lethal,recessive" FBgn0019892 anon-2Be anon-2Be http://flybase.net/reports/FBgn0019892.html gene G-42 16-Dec-15 2015_12 FBgn0082676 E(ftz)723 E(ftz)723 http://flybase.net/reports/FBgn0082676.html gene 723 16-Dec-15 2015_12 FBgn0259252 C155 http://flybase.net/reports/FBgn0259252.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0034218 CG18467 http://flybase.net/reports/FBgn0034218.html protein_coding_gene "IPR006595=CTLH, C-terminal LisH motif, IPR024964=CTLH/CRA C-terminal to LisH motif domain, IPR006594=LIS1 homology motif, IPR013144=CRA domain" CG18467 16-Dec-15 2015_12 viable FBgn0053775 CG33775 http://flybase.net/reports/FBgn0053775.html FBgn0082872 protein_coding_gene "BP1034, unnamed" IPR010512=Protein of unknown function DUF1091 CG33775 16-Dec-15 2015_12 FBgn0262317 mir-966 mir-966 stem loop http://flybase.net/reports/FBgn0262317.html miRNA_gene "dme-mir-966, CR43024, miR-966" CR43024 16-Dec-15 2015_12 viable FBgn0033749 achi achintya http://flybase.net/reports/FBgn0033749.html FBgn0026155 protein_coding_gene "0003714=transcription corepressor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0007283=spermatogenesis, 0045893=positive regulation of transcription, DNA-templated" 0005634=nucleus "achi/vis, CG8819, zaa, ach, dTGIFb, Achi, vis, zuker-aly-like a, TGIF, dTGIF, Achintya, dTGIFa" "IPR009057=Homeodomain-like, IPR008422=Homeobox KN domain, IPR001356=Homeobox domain" CG8819 16-Dec-15 2015_12 "ENSDARG00000002601(irx7),ENSDARG00000009510(irx1a),ENSDARG00000031138(irx3b),ENSDARG00000056594(irx1b),ENSDARG00000067576,ENSDARG00000034043(irx5a)" " adult stage , embryonic stage -- adult stage " " organism

, testis | restricted

, testis

" " adult stage , embryonic stage , larval stage , adult stage | male " " organism

, dorsal mesothoracic disc

, egg chamber

, testis

, spermatid

, spermatocyte

, ovary

" "viable,fertile,male sterile,partially" FBgn0001186 Hex-A Hexokinase A http://flybase.net/reports/FBgn0001186.html FBgn0030140 protein_coding_gene "0005524=ATP binding, 0008865=fructokinase activity, 0004396=hexokinase activity, 0005536=glucose binding, 0004340=glucokinase activity, 0019158=mannokinase activity" "0001678=cellular glucose homeostasis, 0046835=carbohydrate phosphorylation, 0006096=glycolytic process, 0060361=flight" 0005829=cytosol "CG3001, HK-A, Hexokinase, Hex, Hex-A:B, HEX-A, DM1, Hex-A,B, HexA, hexokinase A, HEX, hexokinase, HK" "IPR001312=Hexokinase, IPR022673=Hexokinase, C-terminal, IPR019807=Hexokinase, binding site, IPR022672=Hexokinase, N-terminal" CG3001 16-Dec-15 2015_12 "ENSDARG00000026964(hk2),ENSDARG00000039452(hk1),ENSDARG00000038703(hkdc1),ENSDARG00000068006(gck)" "YFR053C(HXK1),YGL253W(HXK2)" WBGene00008780(F14B4.2) "ENSXETG00000019003(GCK),ENSXETG00000019639()" ENSMUSG00000041798(Gck) "ENSG00000106633(GCK),ENSG00000159399(HK2),ENSG00000156515(HK1),ENSG00000156510(HKDC1)" "lethal,recessive,electrophoretic variant,viable" DRSC25354 EK -0.557254235 0.28752464 1.618160829 -0.015664338 -1.539257741 -0.190955184 FBgn0001758 l(1)M8 lethal (1) M8 http://flybase.net/reports/FBgn0001758.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" adult cuticle FBgn0011960 tRNA:R2:84Fb transfer RNA:arg2:84Fb http://flybase.net/reports/FBgn0011960.html "FBgn0003758, FBgn0011947, FBgn0051566, FBgn0060096" tRNA_gene "0033429=CGU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3R.trna69-ArgACG, tRNA[arg], tRNA:arg1, tRNA:R1, transfer RNA:arg1, tRNA:R:ACG:AE002708-b, tRNA:arg2:84Fb, CR31566, tRNA[Arg][[2]], AE002708.trna63-ArgACG" CR31566 16-Dec-15 2015_12 FBgn0005166 l(2)G560 lethal (2) G560 http://flybase.net/reports/FBgn0005166.html gene 16-Dec-15 2015_12 lethal FBgn0084303 2.14.98 2.14.98 http://flybase.net/reports/FBgn0084303.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0032891 Oseg5 Outer segment 5 http://flybase.net/reports/FBgn0032891.html protein_coding_gene "0042384=cilium assembly, 0035058=nonmotile primary cilium assembly" "0005929=cilium, 0030992=intraciliary transport particle B, 0031513=nonmotile primary cilium" "CHE-2, IFT80, CG9333, oseg5, OSEG, Oseg5, Che-2, OSEG5" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG9333 16-Dec-15 2015_12 ENSDARG00000038879(ift80) WBGene00000484(che-2) ENSXETG00000008716(wdr56) ENSMUSG00000027778(Ift80) ENSG00000068885(IFT80) FBgn0086713 bubbles bubbles http://flybase.net/reports/FBgn0086713.html gene 16-Dec-15 2015_12 FBgn0024740 Lip2 Lipase 2 http://flybase.net/reports/FBgn0024740.html FBgn0032288 protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process "Dmlip2, lipase 2, CG17116, lip2, dilp2" "IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG17116 16-Dec-15 2015_12 "YLR020C(YEH2),YLL012W(YEH1)" "viable,fertile" DRSC02577 K 0.785376123 0.396735545 -0.457651786 -0.157750348 1.594854519 -0.242949338 FBgn0267903 CG46191 http://flybase.net/reports/FBgn0267903.html protein_coding_gene Mst35Ba-related CG46191 16-Dec-15 2015_12 FBgn0264398 FCP-F http://flybase.net/reports/FBgn0264398.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0259789 vfl vielfaltig http://flybase.net/reports/FBgn0259789.html "FBgn0028317, FBgn0031071, FBgn0040186, FBgn0027202, FBgn0043370" protein_coding_gene "0046872=metal ion binding, 0005515=protein binding, 0000976=transcription regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding" "0000278=mitotic cell cycle, 0007349=cellularization, 0044719=regulation of imaginal disc-derived wing size, 0045893=positive regulation of transcription, DNA-templated" "0000785=chromatin, 0005654=nucleoplasm" "lethal (1) G0427, ZELDA, l(1)G0225, Zld, EP1344, Vfl, zelda, l(1)G0427, zinc-finger early Drosophila activator, lethal (1) G0353, CG12701, l(1)G0353, zld, vielfaltig/Zelda, ZLD, Zelda, Vielfaltig, lethal (1) G0225" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR022755=Zinc finger, double-stranded RNA binding, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG12701 16-Dec-15 2015_12 FBgn0034661 CG4386 http://flybase.net/reports/FBgn0034661.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP17 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG4386 16-Dec-15 2015_12 "ENSDARG00000056324(zgc:123295),ENSDARG00000046140(zgc:112038),ENSDARG00000055644(zgc:101788),ENSDARG00000070713(zgc:162180),ENSDARG00000070710(wu:fk80d04),ENSDARG00000061858(zgc:153968),ENSDARG00000056773(zgc:163079),ENSDARG00000052064(LOC571079),ENSDARG00000063444,ENSDARG00000070518,ENSDARG00000019714" WBGene00006619(try-1) ENSXETG00000010124(TEgg123i01.1) "ENSMUSG00000054537(Tmprss11e),ENSMUSG00000048764(Tmprss11f)" viable FBgn0058255 CR40255 http://flybase.net/reports/FBgn0058255.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0265524 CR44374 http://flybase.net/reports/FBgn0265524.html non_protein_coding_gene CR44374 16-Dec-15 2015_12 FBgn0259542 GG01350 http://flybase.net/reports/FBgn0259542.html gene 16-Dec-15 2015_12 visible wing FBgn0259299 C717 http://flybase.net/reports/FBgn0259299.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing margin,chaeta" FBgn0029568 CG11381 http://flybase.net/reports/FBgn0029568.html protein_coding_gene 0042600=chorion CG11381 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0259384 C275 http://flybase.net/reports/FBgn0259384.html gene 16-Dec-15 2015_12 visible "wing hair,wing,wing vein" FBgn0038042 Scgë_ Sarcoglycan ë_ http://flybase.net/reports/FBgn0038042.html protein_coding_gene 0008307=structural constituent of muscle 0007517=muscle organ development "0016021=integral component of membrane, 0016012=sarcoglycan complex" "dscgbeta, beta-sarcolgycan, DmSCG-beta, Scgbeta, CG5657, beta-sarcoglycan, scg-beta" "IPR027659=Beta-sarcoglycan, IPR006875=Sarcoglycan complex subunit protein" CG5657 16-Dec-15 2015_12 ENSDARG00000052341(sgcb) WBGene00019277(sgcb-1) ENSXETG00000011676(SGCB) ENSMUSG00000029156(Sgcb) ENSG00000163069(SGCB) FBgn0061155 l(2)53Da lethal (2) 53Da http://flybase.net/reports/FBgn0061155.html gene l(2)k05207 16-Dec-15 2015_12 "lethal,recessive" FBgn0261562 CG42676 http://flybase.net/reports/FBgn0261562.html "FBgn0035276, FBgn0052317, FBgn0069057, FBgn0035277" protein_coding_gene "CG12022, CG13923, CG32317" CG42676 16-Dec-15 2015_12 DRSC08227 E -0.113685522 0.329132113 1.659188914 -0.869850993 0.167903064 -0.163803597 FBgn0085414 dpr12 defective proboscis extension response 12 http://flybase.net/reports/FBgn0085414.html "FBgn0033044, FBgn0040847" protein_coding_gene "0007606=sensory perception of chemical stimulus, 0008039=synaptic target recognition" "CT34165, CG14469, Dpr-12, dpr12, CG7796, Dpr12, CG34385" "IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG34385 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053630 CG33630 http://flybase.net/reports/FBgn0053630.html FBgn0037784 protein_coding_gene CG12808 IPR006617=Protein of unknown function DM8 CG33630 16-Dec-15 2015_12 FBgn0005089 fs(2)OWc1 female sterile (2) OWc1 http://flybase.net/reports/FBgn0005089.html gene 16-Dec-15 2015_12 FBgn0067640 vag vagabond http://flybase.net/reports/FBgn0067640.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 female sterile "oocyte nucleus,germline clone,follicle cell,oocyte" FBgn0085615 CG41325 http://flybase.net/reports/FBgn0085615.html FBan0041325 protein_coding_gene 16-Dec-15 2015_12 FBgn0000248 cab cabbage http://flybase.net/reports/FBgn0000248.html gene 0008355=olfactory learning 16-Dec-15 2015_12 "learning defective,tarsal response defective" FBgn0027624 17.6\env env http://flybase.net/reports/FBgn0027624.html transposable_element_gene env "IPR012014=Retroelement-encoded protein, env-related" 16-Dec-15 2015_12 FBgn0262564 CR43104 http://flybase.net/reports/FBgn0262564.html non_protein_coding_gene "mdcds_12891, CG43104" CR43104 16-Dec-15 2015_12 FBgn0065971 l(2)45CDa lethal (2) 45CDa http://flybase.net/reports/FBgn0065971.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013750 Arf51F ADP ribosylation factor at 51F http://flybase.net/reports/FBgn0013750.html protein_coding_gene "0003924=GTPase activity, 0003956=NAD(P)+-protein-arginine ADP-ribosyltransferase activity, 0005525=GTP binding" "0015031=protein transport, 0016197=endosomal transport, 0007112=male meiosis cytokinesis, 0030036=actin cytoskeleton organization, 0007283=spermatogenesis, 0007269=neurotransmitter secretion, 0007264=small GTPase mediated signal transduction, 0048488=synaptic vesicle endocytosis, 0006471=protein ADP-ribosylation, 0007520=myoblast fusion, 0048149=behavioral response to ethanol" "0005886=plasma membrane, 0055037=recycling endosome, 0005912=adherens junction, 0005769=early endosome, 0005829=cytosol" "AFR51F, arf51F, d-Arf6, ARFIII, arf6, LD12493, arf51f, EP(2)2612, ARF6, unnamed, P40946, ADP ribosylation factor III, CG8156, dArf6, Dm Arf51F, Arf6, dARFIII, ADP ribosylation factor 51F, Arf51f, ARF3" "IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006689=Small GTPase superfamily, ARF/SAR type, IPR024156=Small GTPase superfamily, ARF type" CG8156 16-Dec-15 2015_12 ENSDARG00000042075 WBGene00000184(arf-6) "ENSXETG00000000038(arf6),ENSXETG00000023978(TGas096a24.1)" ENSMUSG00000044147(Arf6) ENSG00000165527(ARF6) adult stage head

"chemical sensitive,recessive,chemical resistant,cell shape defective,viable,female sterile,partially,male sterile,cytokinesis defective,male" "embryonic myoblast,ventral nerve cord commissure | embryonic stage,retina,spermatid,primary spermatocyte,cleavage furrow & primary spermatocyte" FBgn0019854 anon-TE7 anon-TE7 http://flybase.net/reports/FBgn0019854.html gene TE7 16-Dec-15 2015_12 FBgn0034152 Acp53C14a Accessory gland protein 53C14a http://flybase.net/reports/FBgn0034152.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Acp53, Acp53Ca, Apc53C14a, CG8626, Acp53C14a" IPR009392=Drosophila ACP53EA CG8626 16-Dec-15 2015_12 viable FBgn0263326 CG43407 http://flybase.net/reports/FBgn0263326.html protein_coding_gene CG43407 16-Dec-15 2015_12 FBgn0034495 CG11788 http://flybase.net/reports/FBgn0034495.html protein_coding_gene IPR019128=Sister chromatid cohesion protein Dcc1 CG11788 16-Dec-15 2015_12 ENSDARG00000019907(dscc1) YCL016C(DCC1) WBGene00019595(K09H9.2) ENSXETG00000003126(TNeu038i11.1) ENSMUSG00000022422(Dscc1) ENSG00000136982(DSCC1) viable FBgn0028234 l(3)S003405 lethal (3) S003405 http://flybase.net/reports/FBgn0028234.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022282 l(2)IR24 lethal (2) IR24 http://flybase.net/reports/FBgn0022282.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011703 RnrL Ribonucleoside diphosphate reductase large subunit http://flybase.net/reports/FBgn0011703.html "FBgn0022117, FBgn0026773" protein_coding_gene "0004748=ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, 0005524=ATP binding" "0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0055114=oxidation-reduction process, 0042246=tissue regeneration, 0006260=DNA replication, 0009263=deoxyribonucleotide biosynthetic process" 0005971=ribonucleoside-diphosphate reductase complex "DmRNR1, RNRL, RnrM1, CG5371, RNR1, RntL, ribonucleoside-diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 subunit, l(2)k06709, unnamed" "IPR013346=Ribonucleotide reductase, class I , alpha subunit, IPR000788=Ribonucleotide reductase large subunit, C-terminal, IPR008926=Ribonucleotide reductase R1 subunit, N-terminal, IPR005144=ATP-cone domain, IPR013509=Ribonucleotide reductase large subunit, N-terminal" CG5371 16-Dec-15 2015_12 ENSDARG00000014017(rrm1) "YER070W(RNR1),YIL066C(RNR3)" WBGene00004391(rnr-1) ENSXETG00000003999(RRM1) ENSMUSG00000030978(Rrm1) ENSG00000167325(RRM1) "lethal,recessive,visible,conditional,decreased cell number,increased cell death,viable" "eye disc,conditional,eye,wing,mesothoracic tergum" FBgn0002764 mit(1)14 mitotic 14 http://flybase.net/reports/FBgn0002764.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0070012 BG01257 BG01257 http://flybase.net/reports/FBgn0070012.html gene 16-Dec-15 2015_12 stress response defective FBgn0262679 CG43149 http://flybase.net/reports/FBgn0262679.html protein_coding_gene CG43149 16-Dec-15 2015_12 FBgn0053432 5SrRNA:CR33432 5SrRNA:CR33432 http://flybase.net/reports/FBgn0053432.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33432 CR33432 16-Dec-15 2015_12 FBgn0265376 CR44317 http://flybase.net/reports/FBgn0265376.html non_protein_coding_gene lincRNA.671 CR44317 16-Dec-15 2015_12 FBgn0031505 ND-B14.5B NADH dehydrogenase (ubiquinone) B14.5 B subunit http://flybase.net/reports/FBgn0031505.html FBgn0063038 protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "N4BM, CG12400, NADH:ubiquinone oxidoreductase B14.5B subunit, NADH-ubiquinone oxidoreductase subunit B14.5b, NADH ubiquinone oxidoreductase B14.5B, BcDNA:RE29623" "IPR009423=NADH:ubiquinone oxidoreductase, subunit b14.5b" CG12400 16-Dec-15 2015_12 WBGene00022169(Y71H2AM.4) ENSMUSG00000030647(Ndufc2) ENSG00000151366(NDUFC2-KCTD14) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0060574 l(3)S095714b lethal (3) S095714b http://flybase.net/reports/FBgn0060574.html gene 0957/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0046119 E(To)6 E(To)6 http://flybase.net/reports/FBgn0046119.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065824 l(2)SH0362 lethal (2) SH0362 http://flybase.net/reports/FBgn0065824.html gene l(2)SH2 0362 16-Dec-15 2015_12 "lethal,recessive" FBgn0032259 CG6144 http://flybase.net/reports/FBgn0032259.html protein_coding_gene "0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 0055114=oxidation-reduction process "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR027450=Alpha-ketoglutarate-dependent dioxygenase AlkB-like" CG6144 16-Dec-15 2015_12 WBGene00007202(B0564.2) ENSXETG00000002842(ALKBH6) ENSMUSG00000042831(Alkbh6) ENSG00000221889 viable FBgn0029965 Ir7b Ionotropic receptor 7b http://flybase.net/reports/FBgn0029965.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 7b, IR7b, CG15326, DmelIR7b" CG15326 16-Dec-15 2015_12 FBgn0032386 CG17745 http://flybase.net/reports/FBgn0032386.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000549 Edg43A Ecdysone-dependent gene at 43A http://flybase.net/reports/FBgn0000549.html gene "EDg43, Edg42A" 16-Dec-15 2015_12 prepupal stage epidermis

FBgn0010177 tu(2)1a tu(2)1a http://flybase.net/reports/FBgn0010177.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,partially lethal - majority die" FBgn0002215 l(3)67BDm lethal (3) 67BDm http://flybase.net/reports/FBgn0002215.html gene 16-Dec-15 2015_12 lethal FBgn0283431 CR46274 http://flybase.net/reports/FBgn0283431.html pseudogene_attribute CR46274 16-Dec-15 2015_12 FBgn0000968 fs(2)eo3 female sterile (2) eo3 http://flybase.net/reports/FBgn0000968.html gene "fs(2)eo-F, fs(2)eoRV64" 16-Dec-15 2015_12 female sterile egg chamber FBgn0025134 su(RpII140Z36)S13 su(RpII140Z36)S13 http://flybase.net/reports/FBgn0025134.html gene Z36[S13] 16-Dec-15 2015_12 FBgn0014370 odd-striped odd-striped http://flybase.net/reports/FBgn0014370.html gene 0016021=integral component of membrane ost 16-Dec-15 2015_12 FBgn0052801 CG32801 http://flybase.net/reports/FBgn0052801.html FBgn0029595 protein_coding_gene CG14819 IPR029214=FAM183 family CG32801 16-Dec-15 2015_12 DRSC25614 K 0.087210281 -0.004995594 0.302832784 0.157029665 1.145936083 2.553169582 FBgn0083318 E(smoDN)111 Enhancer of smoDN 111 http://flybase.net/reports/FBgn0083318.html gene 16-Dec-15 2015_12 FBgn0029080 iab-8PRE iab-8 Polycomb group response element http://flybase.net/reports/FBgn0029080.html regulatory_region iab-8 PRE 16-Dec-15 2015_12 FBgn0035265 CG18173 http://flybase.net/reports/FBgn0035265.html protein_coding_gene "0016746=transferase activity, transferring acyl groups" 0006506=GPI anchor biosynthetic process "0005789=endoplasmic reticulum membrane, 0016021=integral component of membrane" IPR009447=GWT1 CG18173 16-Dec-15 2015_12 YJL091C(GWT1) WBGene00022447(Y110A2AL.12) ENSXETG00000002039(PIGW) ENSMUSG00000045140(Pigw) ENSG00000184886(PIGW) viable DRSC08526 K 0.255558973 -0.299240442 -0.116766381 0.394721301 0.222341615 1.520708487 FBgn0060546 l(3)S098905b lethal (3) S098905b http://flybase.net/reports/FBgn0060546.html gene 0989/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0036354 Poc1 Proteome of centrioles 1 http://flybase.net/reports/FBgn0036354.html protein_coding_gene 0051297=centrosome organization "Pix, poc1, CG10191" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG10191 16-Dec-15 2015_12 ENSDARG00000021110(poc1b) "ENSXETG00000021865(wdr51b),ENSXETG00000010813(wdr51a)" "ENSMUSG00000023345(Poc1a),ENSMUSG00000019952(Poc1b)" "ENSG00000139323(POC1B-GALNT4),ENSG00000164087(POC1A)" "viable,fertile" "centriole,spermatocyte,centrioleLy)" FBgn0005765 l(1)TK412 lethal (1) TK412 http://flybase.net/reports/FBgn0005765.html gene l412 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0066306 Bexon.s Bexon.s http://flybase.net/reports/FBgn0066306.html gene Bexon s 16-Dec-15 2015_12 FBgn0083007 snoRNA:ë¬28S-1135f snoRNA:ë¬28S-1135f http://flybase.net/reports/FBgn0083007.html snoRNA_gene "psi28S-1135f, CR34599, Psi28S-1135f" CR34599 16-Dec-15 2015_12 FBgn0028144 l(3)S045902 lethal (3) S045902 http://flybase.net/reports/FBgn0028144.html gene 0459/02 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0031294 IA-2 IA-2 protein tyrosine phosphatase http://flybase.net/reports/FBgn0031294.html "FBgn0031297, FBgn0045882, FBgn0051795" protein_coding_gene "0008270=zinc ion binding, 0005001=transmembrane receptor protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0048565=digestive tract development, 0051046=regulation of secretion, 0006470=protein dephosphorylation" 0005886=plasma membrane "anon-WO0153538.69, CG4355, unnamed, CG31795, Ia2, CG11344, R-PTPX/1A2, ia2, IA-2 ortholog" "IPR015940=Ubiquitin-associated domain, IPR000242=PTP type protein phosphatase, IPR000387=Tyrosine specific protein phosphatases domain, IPR029021=Protein-tyrosine phosphatase-like, IPR000270=PB1 domain, IPR021613=Protein-tyrosine phosphatase receptor IA-2 ectodomain, IPR009060=UBA-like, IPR000433=Zinc finger, ZZ-type" CG31795 16-Dec-15 2015_12 WBGene00002048(ida-1) "ENSMUSG00000026204(Ptprn),ENSMUSG00000056553(Ptprn2)" "ENSG00000155093(PTPRN2),ENSG00000054356(PTPRN)" "partially lethal - majority die,some die during pupal stage,viable" "pupal cuticle,pupal abdomen" FBgn0260378 GSd469 http://flybase.net/reports/FBgn0260378.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0002993 olfP olfactory P http://flybase.net/reports/FBgn0002993.html gene 16-Dec-15 2015_12 FBgn0050281 CG30281 http://flybase.net/reports/FBgn0050281.html FBgn0034696 protein_coding_gene "CG6676, FBpp0071674, Fibrinogen-related protein, AAM68209" "IPR020837=Fibrinogen, conserved site, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain" CG30281 16-Dec-15 2015_12 ENSDARG00000060393(LOC567525) WBGene00020516(T15B7.1) "ENSXETG00000006277(),ENSXETG00000024468(),ENSXETG00000024469(),ENSXETG00000024470(),ENSXETG00000000396(BC089673.1),ENSXETG00000024910(BC075449.1),ENSXETG00000008638(fcn1),ENSXETG00000001807(),ENSXETG00000007176(BC090364.1)" "ENSMUSG00000026841(Fibcd1),ENSMUSG00000026938(Fcna),ENSMUSG00000026835(Fcnb)" ENSG00000130720(FIBCD1) FBgn0025644 CG14424 http://flybase.net/reports/FBgn0025644.html protein_coding_gene EG:100G7.5 CG14424 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0038415 CG17929 http://flybase.net/reports/FBgn0038415.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG17929 16-Dec-15 2015_12 viable FBgn0002449 l(3)SG2 lethal (3) SG2 http://flybase.net/reports/FBgn0002449.html gene l(3)13m-237 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0033691 CG8860 http://flybase.net/reports/FBgn0033691.html FBgn0063198 protein_coding_gene "0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity, 0008565=protein transporter activity" "0006616=SRP-dependent cotranslational protein targeting to membrane, translocation, 0022008=neurogenesis" 0005784=Sec61 translocon complex BcDNA:GM14157 "IPR001901=Protein translocase complex, SecE/Sec61-gamma subunit, IPR023391=Protein translocase SecE domain, IPR022943=Preprotein translocase subunit SecE, IPR008158=Protein translocase SEC61 complex, gamma subunit" CG8860 16-Dec-15 2015_12 ENSDARG00000018637(sec61g) YDR086C(SSS1) WBGene00001303(emo-1) ENSXETG00000015843(SEC61G) "ENSMUSG00000078974(Sec61g),ENSMUSG00000078109(Gm4184)" ENSG00000132432(SEC61G) "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0004189 snRNA:U6:96Ab small nuclear RNA U6 at 96Ab http://flybase.net/reports/FBgn0004189.html "FBgn0003455, FBgn0003939, FBgn0003940" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005688=U6 snRNP "U6 small nuclear RNA, U6 RNA, U6-2, U6snRNA, U6-96Ab, snRNA6, U6:96Ab, DU6-2, small nuclear RNA b, U6, U6 snRNA, U6snRNA96Ab, CR32867, K1, snRNA4, snRNA:U6, dU6, snRNA-b, snRNA[[4]], small nuclear RNA U6, U6-2 small nuclear RNA" CR32867 16-Dec-15 2015_12 FBgn0053965 CG33965 http://flybase.net/reports/FBgn0053965.html FBgn0035191 protein_coding_gene "0008431=vitamin E binding, 0005215=transporter activity" 0006810=transport 0005622=intracellular CG1211 "IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR000595=Cyclic nucleotide-binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG33965 16-Dec-15 2015_12 FBgn0035741 BBS1 Bardet-Biedl syndrome 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0035741.html protein_coding_gene "0042384=cilium assembly, 0035058=nonmotile primary cilium assembly" "0034464=BBSome, 0005929=cilium" "CG14825, BBS1" IPR028784=Bardet-Biedl syndrome 1 protein CG14825 16-Dec-15 2015_12 WBGene00000241(bbs-1) ENSXETG00000026165() ENSMUSG00000006464(Bbs1) ENSG00000174483(BBS1) viable FBgn0032929 Mcm10 Minichromosome maintenance 10 http://flybase.net/reports/FBgn0032929.html FBgn0044408 protein_coding_gene 0003682=chromatin binding "0035214=eye-antennal disc development, 0042023=DNA endoreduplication, 0030261=chromosome condensation, 0006260=DNA replication, 0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0045678=positive regulation of R7 cell differentiation, 1901693=negative regulation of compound eye retinal cell apoptotic process, 0016321=female meiosis chromosome segregation, 0070868=heterochromatin organization involved in chromatin silencing, 0045931=positive regulation of mitotic cell cycle" "0005656=nuclear pre-replicative complex, 0005634=nucleus" "mcm10, CG9241, DmMCM10, Scim19, dMcm10, Sensitized chromosome inheritance modifier 19" "IPR015411=Replication factor Mcm10, IPR015408=Zinc finger, Mcm10/DnaG-type" CG9241 16-Dec-15 2015_12 ENSDARG00000045815(mcm10) YIL150C(MCM10) WBGene00012935(Y47D3A.28) ENSXETG00000009113(mcm10) ENSMUSG00000026669(Mcm10) ENSG00000065328(MCM10) "viable,partially lethal - majority die,recessive,mitotic cell cycle defective,suppressor of variegation,dominant,small body,increased cell death,lethal - all die during pupal stage" "condensed nuclear chromosome,embryonic/larval brain,nurse cell,polytene chromosome,nuclear chromosome,eye,ommatidium,eye disc,photoreceptor cell R7 | third instar larval stage,photoreceptor cell R7" FBgn0058088 CG40088 http://flybase.net/reports/FBgn0058088.html FBan0040088 protein_coding_gene 16-Dec-15 2015_12 FBgn0025334 PHDP Putative homeodomain protein http://flybase.net/reports/FBgn0025334.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG11182, anon-60Ac, unnamed" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG11182 16-Dec-15 2015_12 WBGene00000440(ceh-17) viable FBgn0060999 l(3)S027005 lethal (3) S027005 http://flybase.net/reports/FBgn0060999.html gene 0270/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0004526 l(4)102CDi lethal (4) 102CDi http://flybase.net/reports/FBgn0004526.html gene "l(4)14, l(4)CDi, l(4)ST-2, l(4)26, lethal(4) Solway, Tennessee-2" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0031715 tomb tombola http://flybase.net/reports/FBgn0031715.html protein_coding_gene 0005515=protein binding "0051039=positive regulation of transcription during meiosis, 0007140=male meiosis" 0000790=nuclear chromatin "Tomb, CG14016" "IPR028307=Lin-54 family, IPR005172=CRC domain" CG14016 16-Dec-15 2015_12 ENSXETG00000025295(MTL5) "viable,male sterile,meiotic cell cycle defective,male,female fertile" "testis,nuclear chromosome & primary spermatocyte" FBgn0031772 CG13994 http://flybase.net/reports/FBgn0031772.html "FBgn0061429, FBgn0064986" protein_coding_gene "0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium" 0000164=protein phosphatase type 1 complex BcDNA:AT31406 IPR011107=Protein phosphatase inhibitor CG13994 16-Dec-15 2015_12 ENSDARG00000036063(ppp1r11) "WBGene00015579(C07H6.2),WBGene00010763(K10H10.7)" ENSXETG00000024449(BC074590.1) ENSMUSG00000036398(Ppp1r11) "ENSG00000206501,ENSG00000112498,ENSG00000204619(PPP1R11)" "lethal,lethal - all die before end of pupal stage,some die during pupal stage,viable" embryonic/larval brain FBgn0020841 l(2)BV238 "Blacksburg, VA 238" http://flybase.net/reports/FBgn0020841.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005095 fs(2)OWc7 female sterile (2) OWc7 http://flybase.net/reports/FBgn0005095.html gene 16-Dec-15 2015_12 FBgn0038244 CG7987 http://flybase.net/reports/FBgn0038244.html FBgn0062149 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" anon-WO0118547.245 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7987 16-Dec-15 2015_12 viable FBgn0003411 sisA sisterless A http://flybase.net/reports/FBgn0003411.html protein_coding_gene "0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity, 0005515=protein binding" "0007496=anterior midgut development, 0007540=sex determination, establishment of X:A ratio, 0007530=sex determination, 0007497=posterior midgut development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007492=endoderm development, 0007538=primary sex determination" 0005634=nucleus "sis A, sis-a, DM29, sisa, sisterless a, sis-A, CG1641, sis a" CG1641 16-Dec-15 2015_12 " embryonic stage , embryonic stage | cycle 8-14 " " yolk nucleus

, cleavage nucleus

" "lethal,male,recessive,heat sensitive,female,partially,wild-type,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval midgut,anterior,posterior embryonic/larval midgut,yolk,yolk granule" FBgn0084949 S50.3 S50.3 http://flybase.net/reports/FBgn0084949.html gene 16-Dec-15 2015_12 "visible,fertile" eye FBgn0038960 CG13855 http://flybase.net/reports/FBgn0038960.html protein_coding_gene CG13855 16-Dec-15 2015_12 ENSDARG00000061899(LOC100334576) ENSXETG00000022138(IQUB) ENSMUSG00000046192(Iqub) ENSG00000164675(IQUB) viable FBgn0004530 l(4)102CDl lethal (4) 102CDl http://flybase.net/reports/FBgn0004530.html gene "l(4)22, l(4)AM-1, lethal(4) Amherst, Massachusetts-1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0061002 l(3)S026543b lethal (3) S026543b http://flybase.net/reports/FBgn0061002.html gene 0265/43 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031560 CG16713 http://flybase.net/reports/FBgn0031560.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0046331=lateral inhibition CT37195 "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG16713 16-Dec-15 2015_12 ENSDARG00000069736 ENSXETG00000016886(SPINT3) "ENSMUSG00000074595(Wfdc6a),ENSMUSG00000070531(Wfdc6b),ENSMUSG00000017733(Spinlw1)" "viable,visible" "chaeta,supernumerary" FBgn0031950 Herp Homocysteine-induced endoplasmic reticulum protein http://flybase.net/reports/FBgn0031950.html protein_coding_gene "0006983=ER overload response, 0030968=endoplasmic reticulum unfolded protein response" "0005875=microtubule associated complex, 0005783=endoplasmic reticulum" "herp, homocysteine-induced endoplasmic reticulum protein, dHerp, CG14536, CG1453" "IPR000626=Ubiquitin domain, IPR029071=Ubiquitin-related domain" CG14536 16-Dec-15 2015_12 "ENSDARG00000021033(herpud2),ENSDARG00000024314(herpud1)" WBGene00009112(tag-353) "ENSXETG00000013111(TEgg004b20.1),ENSXETG00000026099(Herpud1)" "ENSMUSG00000008429(Herpud2),ENSMUSG00000031770(Herpud1)" "ENSG00000122557(HERPUD2),ENSG00000051108(HERPUD1)" "viable,fertile" FBgn0260332 GSd204 http://flybase.net/reports/FBgn0260332.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0033076 CG15233 http://flybase.net/reports/FBgn0033076.html FBgn0046273 protein_coding_gene BEST:LD11861 CG15233 16-Dec-15 2015_12 viable FBgn0060483 l(3)S110812 lethal (3) S110812 http://flybase.net/reports/FBgn0060483.html gene 1108/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0050159 CG30159 http://flybase.net/reports/FBgn0050159.html FBgn0033123 protein_coding_gene CG3364 CG30159 16-Dec-15 2015_12 ENSMUSG00000048581(E130311K13Rik) viable FBgn0026412 Leucine-aminopeptidase Leucine aminopeptidase http://flybase.net/reports/FBgn0026412.html gene 0004177=aminopeptidase activity leucyl aminopeptidase 16-Dec-15 2015_12 FBgn0083151 S(smoDN)204 Suppressor of smoDN 204 http://flybase.net/reports/FBgn0083151.html gene 16-Dec-15 2015_12 FBgn0261927 CR42794 http://flybase.net/reports/FBgn0261927.html non_protein_coding_gene CG42794 CR42794 16-Dec-15 2015_12 FBgn0032116 Mco1 Multicopper oxidase-1 http://flybase.net/reports/FBgn0032116.html protein_coding_gene "0005381=iron ion transmembrane transporter activity, 0004322=ferroxidase activity, 0005507=copper ion binding" "0055114=oxidation-reduction process, 0055072=iron ion homeostasis" "0031233=intrinsic component of external side of plasma membrane, 0009986=cell surface, 0045178=basal part of cell" "CG3759, MCO1, multicopper oxidase-1, laccase-like" "IPR008972=Cupredoxin, IPR001007=VWFC domain, IPR002355=Multicopper oxidase, copper-binding site, IPR001117=Multicopper oxidase, type 1, IPR011706=Multicopper oxidase, type 2, IPR011707=Multicopper oxidase, type 3" CG3759 16-Dec-15 2015_12 "YMR058W(FET3),YFL041W(FET5)" WBGene00009008(F21D5.3) "viable,chemical resistant,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC02720 K 0.273267251 0.381731379 -0.434762187 -0.004356263 1.38288874 1.757601482 FBgn0000614 Ext Extras http://flybase.net/reports/FBgn0000614.html gene 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" wing vein FBgn0035146 CG13893 http://flybase.net/reports/FBgn0035146.html protein_coding_gene 0005215=transporter activity 0006810=transport "0016021=integral component of membrane, 0005622=intracellular" "IPR011074=CRAL/TRIO, N-terminal domain, IPR009038=GOLD domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG13893 16-Dec-15 2015_12 ENSDARG00000059729(si:ch211-89f7.1) "YMR079W(SEC14),YKL091C()" WBGene00010370(ctg-1) ENSXETG00000016146() "ENSMUSG00000003585(Sec14l2),ENSMUSG00000054986(Sec14l3),ENSMUSG00000019368(Sec14l4)" "ENSG00000100003(SEC14L2),ENSG00000100012(SEC14L3),ENSG00000133488(SEC14L4),ENSG00000214491(SEC14L6)" "viable,fertile" FBgn0085246 CG34217 http://flybase.net/reports/FBgn0085246.html protein_coding_gene CG34217 16-Dec-15 2015_12 FBgn0001352 l(1)1EFa lethal (1) 1EFa http://flybase.net/reports/FBgn0001352.html gene l(1)BA1 16-Dec-15 2015_12 lethal FBgn0036105 Blos4 "Biogenesis of lysosome-related organelles complex 1, subunit 4" http://flybase.net/reports/FBgn0036105.html protein_coding_gene 0005515=protein binding 0008057=eye pigment granule organization 0031083=BLOC-1 complex "Cappuccino, NP_648414, Dm Blos4, blos4, CG14149, cappuccino, BLOC-1 subunit 4" IPR024857=Cappuccino CG14149 16-Dec-15 2015_12 ENSDARG00000007597(cno) ENSXETG00000025941(cno) ENSMUSG00000060708(Cno) "ENSG00000186222(CNO),ENSG00000124243(BCAS4)" "eye color defective,viable" FBgn0011330 l(3)j2C3 lethal (3) j2C3 http://flybase.net/reports/FBgn0011330.html gene 16-Dec-15 2015_12 lethal FBgn0265303 CR44276 http://flybase.net/reports/FBgn0265303.html non_protein_coding_gene CR44276 16-Dec-15 2015_12 FBgn0035323 CG13807 http://flybase.net/reports/FBgn0035323.html protein_coding_gene 0003723=RNA binding "0046331=lateral inhibition, 0032259=methylation" 0005845=mRNA cap binding complex IPR028271=RNMT-activating mini protein CG13807 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0003011 ort ora transientless http://flybase.net/reports/FBgn0003011.html "FBgn0016658, FBgn0038726" protein_coding_gene "0019182=histamine-gated chloride channel activity, 0005230=extracellular ligand-gated ion channel activity" "0009636=response to toxic substance, 0043052=thermotaxis, 0030534=adult behavior, 0045472=response to ether, 0006821=chloride transport, 0007268=synaptic transmission" "0016021=integral component of membrane, 0019183=histamine-gated chloride channel complex" "HisCl2, outer-rhabdomeres-absent, glycine receptor alpha2-like, outer rhabdomeres transientless, hclA, Hist1, GluCI, HisCl-alpha1, Dm-hclA, histamine-gated chloride channel subunit 1, HA-CI I, hisCl2, indefinite, outer rhabdomere absent, CT22815, HisCI2, outer rhabdomeres absent, Ort, HisCl, DmHisCl2, ora, HisC12, ORT, Histamine-gated chloride channel subunit 2, HclA, DMHisClalpha1, CG7411" "IPR006201=Neurotransmitter-gated ion-channel, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site" CG7411 16-Dec-15 2015_12 adult stage " head

, lamina && medulla && lobula && brain | medial && photoreceptor

" "viable,fertile,neurophysiology defective,chemical sensitive,phototaxis defective,optomotor response defective,thermotaxis behavior defective,recessive,poor,conditional,reduced,chemical resistant,visual behavior defective,behavior defective,paralytic,heat sensitive" "rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell" FBgn0033155 Br140 http://flybase.net/reports/FBgn0033155.html protein_coding_gene 0008270=zinc ion binding 0033563=dorsal/ventral axon guidance CG1845 "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR000313=PWWP domain, IPR019542=Enhancer of polycomb-like, N-terminal, IPR001487=Bromodomain, IPR019787=Zinc finger, PHD-finger, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR001965=Zinc finger, PHD-type" CG1845 16-Dec-15 2015_12 "ENSDARG00000051798(zgc:158610),ENSDARG00000013596(brd1)" WBGene00003034(lin-49) ENSXETG00000014519(brd1) "ENSMUSG00000022387(Brd1),ENSMUSG00000063952(Brpf3),ENSMUSG00000001632(Brpf1)" "ENSG00000100425(BRD1),ENSG00000096070(BRPF3),ENSG00000156983(BRPF1)" "neuroanatomy defective,somatic clone,viable,fertile,visible" "axon | somatic clone | third instar larval stage,mesothoracic tergum" FBgn0034882 CG5398 http://flybase.net/reports/FBgn0034882.html FBgn0044728 protein_coding_gene "0015250=water channel activity, 0015267=channel activity" 0055085=transmembrane transport 0016021=integral component of membrane "Aqp5398, anon-WO0140519.151" "IPR000425=Major intrinsic protein, IPR023271=Aquaporin-like" CG5398 16-Dec-15 2015_12 YPR192W(AQY1) viable FBgn0037921 CG6808 http://flybase.net/reports/FBgn0037921.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus CG31372 "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG6808 16-Dec-15 2015_12 WBGene00004335(ref-2) viable DRSC14934 I -0.236061377 1.744418692 0.074367332 0.163766252 0.226339758 0.765332869 FBgn0263339 CR43420 http://flybase.net/reports/FBgn0263339.html non_protein_coding_gene CR43420 16-Dec-15 2015_12 FBgn0065093 snmRNA:430 small non-messenger RNA 430 http://flybase.net/reports/FBgn0065093.html non_protein_coding_gene Dm-430 16-Dec-15 2015_12 FBgn0262367 mir-13b-1 mir-13b-1 stem loop http://flybase.net/reports/FBgn0262367.html "FBgn0046829, FBgn0262171" miRNA_gene "dme-mir-13b, dme-miR-13b-3p, miR-13, dme-miR-13b, mir-13b, miR-13b-1, mir-13, miR-13B, CR32933, 13b-1, 13b-1/2, Dme-miR-13b, dme-mir-13b-1, mir-13b-1, miRNA-13b, CR42878, miRNA-13b-1, miR-13b" CR42878 16-Dec-15 2015_12 embryonic stage -- adult stage viable FBgn0038418 pad poils au dos http://flybase.net/reports/FBgn0038418.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0008407=chaeta morphogenesis" 0005634=nucleus CG10309 "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR030450=Transcription factor Sp1 family" CG10309 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,viable,recessive,fertile" "mesothoracic tergum & macrochaeta | ectopic,microchaeta,leg,mesothoracic tergum & macrochaeta | ectopicsbd26),mesothoracic tergum & macrochaeta | ectopicP115),anterior scutellar bristle,female,supernumerary,posterior postalar bristle,posterior supraalar bristle,presutural bristle,mesothoracic tergum & microchaeta,sensillum campaniformium & wing | supernumerary" FBgn0032334 CG14914 http://flybase.net/reports/FBgn0032334.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0053552 CG33552 http://flybase.net/reports/FBgn0053552.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0005634=nucleus "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG33552 16-Dec-15 2015_12 viable FBgn0035360 CG1246 http://flybase.net/reports/FBgn0035360.html protein_coding_gene CG1246 16-Dec-15 2015_12 FBgn0266845 CG45307 http://flybase.net/reports/FBgn0266845.html protein_coding_gene lincRNA.77 CG45307 16-Dec-15 2015_12 FBgn0011585 dame daughterless maternal enhancer http://flybase.net/reports/FBgn0011585.html gene E(2)AX 16-Dec-15 2015_12 FBgn0033705 CG13168 http://flybase.net/reports/FBgn0033705.html protein_coding_gene CG13168 16-Dec-15 2015_12 ENSDARG00000035551(si:dkey-125i10.6) "partially lethal - majority die,some die during pupal stage" FBgn0259757 ms(2)Fra-39 http://flybase.net/reports/FBgn0259757.html gene "0051276=chromosome organization, 0007283=spermatogenesis" 16-Dec-15 2015_12 male sterile "Y chromosome loop,spermatozoon" FBgn0265317 CG44290 http://flybase.net/reports/FBgn0265317.html protein_coding_gene lincRNA.869 CG44290 16-Dec-15 2015_12 FBgn0266413 CR45053 http://flybase.net/reports/FBgn0266413.html non_protein_coding_gene CR45053 16-Dec-15 2015_12 FBgn0060785 l(3)S059706a lethal (3) S059706a http://flybase.net/reports/FBgn0060785.html gene 0597/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0027558 pgant3 polypeptide GalNAc transferase 3 http://flybase.net/reports/FBgn0027558.html FBgn0062232 protein_coding_gene "0016757=transferase activity, transferring glycosyl groups, 0008376=acetylgalactosaminyltransferase activity, 0004653=polypeptide N-acetylgalactosaminyltransferase activity" "0009312=oligosaccharide biosynthetic process, 0033628=regulation of cell adhesion mediated by integrin, 0016266=O-glycan processing, 0031589=cell-substrate adhesion, 0070278=extracellular matrix constituent secretion, 0006493=protein O-linked glycosylation" "0005795=Golgi stack, 0005794=Golgi apparatus" "anon-WO0118547.119, CG4445, BcDNA:GH09147" "IPR001173=Glycosyltransferase 2-like, IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain" CG4445 16-Dec-15 2015_12 "visible,viable,lethal,partially lethal - majority die,recessive,fertile" "wing blade,wing disc" FBgn0052733 CR32733 http://flybase.net/reports/FBgn0052733.html pseudogene_attribute CG32733 CR32733 16-Dec-15 2015_12 FBgn0259671 B1522 http://flybase.net/reports/FBgn0259671.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,mediproboscis,proboscis" FBgn0052528 parvin parvin http://flybase.net/reports/FBgn0052528.html FBgn0031067 protein_coding_gene 0003779=actin binding "0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0031532=actin cytoskeleton reorganization, 0007155=cell adhesion, 0016203=muscle attachment" 0005925=focal adhesion "parvin, CG12533, Parvin, CG32528" "IPR001715=Calponin homology domain, IPR028433=Parvin" CG32528 16-Dec-15 2015_12 "ENSDARG00000035629(LOC100331103),ENSDARG00000043710(parvaa),ENSDARG00000019117" WBGene00003932(pat-6) ENSXETG00000004872(parvb) "ENSMUSG00000022438(Parvb),ENSMUSG00000030770(Parva)" "ENSG00000197702(PARVA),ENSG00000188677(PARVB)" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,flight defective,lethal,small body,lethal - all die before end of larval stage,some die during larval stage" "wing,embryonic/larval somatic muscle" FBgn0060418 l(3)S129217b lethal (3) S129217b http://flybase.net/reports/FBgn0060418.html gene 1292/17 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0259978 vlc vulcan http://flybase.net/reports/FBgn0259978.html "FBgn0010633, FBgn0033036, FBgn0061521, FBgn0014098" protein_coding_gene "0007480=imaginal disc-derived leg morphogenesis, 0023052=signaling" 0005918=septate junction "transcription unit X, anon-41Fa, X, anon-WO0118547.98, l(2)07022, unnamed, Vulcan, CG8390" IPR005026=SAPAP family CG8390 16-Dec-15 2015_12 "ENSDARG00000037415,ENSDARG00000014280(dlgap1),ENSDARG00000059340,ENSDARG00000011903,ENSDARG00000055459(si:ch211-250g4.1)" "ENSXETG00000011595(DLGAP2),ENSXETG00000007097(DLGAP3),ENSXETG00000017308(DLGAP4)" "ENSG00000170579(DLGAP1),ENSG00000198010(DLGAP2),ENSG00000080845(DLGAP4),ENSG00000116544(DLGAP3)" " embryonic stage | 3.5 hr , larval stage && pupal stage " " cephalic furrow

, ventral furrow

" FBgn0065446 l(2)SH1419 lethal (2) SH1419 http://flybase.net/reports/FBgn0065446.html gene l(2)SH2 1419 16-Dec-15 2015_12 "lethal,recessive" FBgn0266034 CR44799 http://flybase.net/reports/FBgn0266034.html non_protein_coding_gene lincRNA.71 CR44799 16-Dec-15 2015_12 FBgn0030514 CG9941 http://flybase.net/reports/FBgn0030514.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination "A, x93" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG9941 16-Dec-15 2015_12 "ENSDARG00000057481(LOC555415),ENSDARG00000018347(LOC100334163),ENSDARG00000004796(LOC553327)" WBGene00007529(C11H1.3) "ENSXETG00000019548(RNF157),ENSXETG00000015551(MGRN1)" "ENSMUSG00000052949,ENSMUSG00000022517(Mgrn1)" "ENSG00000141576(RNF157),ENSG00000102858(MGRN1)" viable heart primordium FBgn0013233 E(var)1847 E(var)1847 http://flybase.net/reports/FBgn0013233.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0039337 MED28 Mediator complex subunit 28 http://flybase.net/reports/FBgn0039337.html FBgn0063182 protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0022008=neurogenesis, 0006357=regulation of transcription from RNA polymerase II promoter" "0016592=mediator complex, 0005634=nucleus" "BcDNA:GM31575, Med28, CG5121, dMED23, Med23" "IPR021640=Mediator complex, subunit Med28" CG5121 16-Dec-15 2015_12 ENSDARG00000037410(zgc:103633) ENSXETG00000020344(MED28) ENSMUSG00000015804(Med28) ENSG00000118579(MED28) "lethal,neuroanatomy defective" ganglion mother cell FBgn0035851 MED24 Mediator complex subunit 24 http://flybase.net/reports/FBgn0035851.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0035070=salivary gland histolysis, 0048813=dendrite morphogenesis, 0035209=pupal development, 0043067=regulation of programmed cell death, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0007517=muscle organ development, 0043068=positive regulation of programmed cell death, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process" "0005634=nucleus, 0016592=mediator complex" "CG7999, med24, l(3)psg5, psg5, Mediator, dTRAP100, Trap100, Med24" "IPR021429=Mediator complex, subunit Med24, N-terminal" CG7999 16-Dec-15 2015_12 ENSDARG00000032459(med24) ENSXETG00000013814(MED24) ENSMUSG00000017210(Med24) ENSG00000008838(MED24) "lethal,some die during P-stage,lethal - all die before end of P-stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage,cell death defective,viable,visible,planar polarity defective" "embryonic/larval salivary gland,trichogen cell" DRSC10944 K 0.55252296 0.883296825 -0.498704461 0.373143108 1.08801076 1.877401702 FBgn0053272 CG33272 http://flybase.net/reports/FBgn0053272.html FBgn0036167 protein_coding_gene "HDC09626, inverted repeat 1', unnamed, CG17981" CG33272 16-Dec-15 2015_12 DRSC09116 K 0.7754584 1.747758487 FBgn0035518 CG15011 http://flybase.net/reports/FBgn0035518.html protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus cg15011 "IPR019786=Zinc finger, PHD-type, conserved site, IPR001841=Zinc finger, RING-type, IPR000967=Zinc finger, NF-X1-type" CG15011 16-Dec-15 2015_12 ENSDARG00000070127 ENSXETG00000009836(NFXL1) ENSMUSG00000072889(Nfxl1) ENSG00000170448(NFXL1) "viable,fertile" DRSC08464 K 0.507570659 -1.473295953 0.008633084 -0.033261132 0.896629729 -2.09806905 FBgn0045039 l(2)Hr45-cII lethal (2) Hr45-cII http://flybase.net/reports/FBgn0045039.html gene 16-Dec-15 2015_12 lethal FBgn0067865 Mod(Prat:bw)Y-1 Mod(Prat:bw)Y-1 http://flybase.net/reports/FBgn0067865.html gene Mod-Y-1 16-Dec-15 2015_12 suppressor of variegation FBgn0029590 CG14811 http://flybase.net/reports/FBgn0029590.html protein_coding_gene CG14811 16-Dec-15 2015_12 viable FBgn0043863 pf-3 pairing failure-3 http://flybase.net/reports/FBgn0043863.html gene 0007140=male meiosis "CG3, Complementation group 3" 16-Dec-15 2015_12 FBgn0262316 mir-986 mir-986 stem loop http://flybase.net/reports/FBgn0262316.html miRNA_gene 0046716=muscle cell cellular homeostasis "dme-mir-986, CR43023, dme-miR-986-3p, miR-986" CR43023 16-Dec-15 2015_12 viable FBgn0020808 mfs(3)D4 mfs(3)D4 http://flybase.net/reports/FBgn0020808.html gene 3-D4 16-Dec-15 2015_12 "male sterile,recessive,female sterile,chemical sensitive" FBgn0023115 anon-10As anon-10As http://flybase.net/reports/FBgn0023115.html gene 12 16-Dec-15 2015_12 FBgn0065451 l(2)SH1400 lethal (2) SH1400 http://flybase.net/reports/FBgn0065451.html gene l(2)SH2 1400 16-Dec-15 2015_12 "lethal,recessive" FBgn0000412 D1 D1 chromosomal protein http://flybase.net/reports/FBgn0000412.html protein_coding_gene "0003690=double-stranded DNA binding, 0003680=AT DNA binding, 0003696=satellite DNA binding" "0000786=nucleosome, 0005700=polytene chromosome, 0005737=cytoplasm, 0005634=nucleus" "RE69409, dHMGx, HMGI, Chromosomal protein D1, EP(3)0473, dD1, CG9745" "IPR017956=AT hook, DNA-binding motif, IPR020478=AT hook-like" CG9745 16-Dec-15 2015_12 "viable,lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0052318 CG32318 http://flybase.net/reports/FBgn0052318.html protein_coding_gene "0003777=microtubule motor activity, 0008017=microtubule binding, 0005524=ATP binding" 0007018=microtubule-based movement 0005871=kinesin complex "CG32318-PA, CR32318" "IPR001752=Kinesin motor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027640=Kinesin-like protein" CG32318 16-Dec-15 2015_12 "ENSDARG00000055231,ENSDARG00000060531" FBgn0045046 fs(1)3 female sterile (1) 3 http://flybase.net/reports/FBgn0045046.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0036332 CG11261 http://flybase.net/reports/FBgn0036332.html protein_coding_gene 0031625=ubiquitin protein ligase binding "0006511=ubiquitin-dependent protein catabolic process, 0030163=protein catabolic process" "0019005=SCF ubiquitin ligase complex, 0000152=nuclear ubiquitin ligase complex" "CUL6, Cullin6" "IPR016158=Cullin homology, IPR001373=Cullin, N-terminal, IPR016159=Cullin repeat-like-containing domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019559=Cullin protein, neddylation domain" CG11261 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0027952 mei(2)yh92 mei(2)yh92 http://flybase.net/reports/FBgn0027952.html gene 0007060=male meiosis chromosome segregation mei-yh92 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "meiosis & nuclear chromosome,meiotic metaphase I,meiotic anaphase I | male" FBgn0086319 JV282 http://flybase.net/reports/FBgn0086319.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0037515 Sp7 Serine protease 7 http://flybase.net/reports/FBgn0037515.html FBgn0040241 protein_coding_gene "0004252=serine-type endopeptidase activity, 0004185=serine-type carboxypeptidase activity, 0008236=serine-type peptidase activity" "0035008=positive regulation of melanization defense response, 0006508=proteolysis, 0006952=defense response, 0035006=melanization defense response" 0005576=extracellular region "Sp 7, anon-Ryu, CG3066, serine protease 7, PAE, SP7, PAE1, MP2, sp7, Melanization Protease 2, proPO-AE, prophenoloxidase-activating enzyme" "IPR001254=Serine proteases, trypsin domain, IPR006604=Disulphide knot CLIP, IPR001314=Peptidase S1A, chymotrypsin-type, IPR022700=Proteinase, regulatory CLIP domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG3066 16-Dec-15 2015_12 "viable,melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage,lethal,wound healing defective,immune response defective,partially" "melanotic mass | larval stage,melanotic mass | P-stage,melanotic mass | adult stage,melanotic mass,embryonic/larval hemolymph | third instar larval stage" FBgn0022288 l(2)09851 lethal (2) 09851 http://flybase.net/reports/FBgn0022288.html "FBgn0022053, FBgn0033037" protein_coding_gene "CG12792, l(2)k08138, I(2)09851, GRWD1" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR022052=Histone-binding protein RBBP4, N-terminal, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG12792 16-Dec-15 2015_12 ENSDARG00000004806(grwd1) YMR131C(RRB1) WBGene00021899(Y54H5A.1) ENSXETG00000004598(grwd1) ENSMUSG00000053801(Grwd1) ENSG00000105447(GRWD1) "lethal,recessive,viable,visible" trichogen cell FBgn0039783 PH4ë±NE2 prolyl-4-hydroxylase-alpha NE2 http://flybase.net/reports/FBgn0039783.html protein_coding_gene "0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0032504=multicellular organism reproduction, 0016477=cell migration" "0005615=extracellular space, 0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" "PH4alphaNE2, CG9720" "IPR011990=Tetratricopeptide-like helical domain, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG9720 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0038951 CG5380 http://flybase.net/reports/FBgn0038951.html protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0022008=neurogenesis, 0006383=transcription from RNA polymerase III promoter, 0006351=transcription, DNA-templated" "0005634=nucleus, 0005666=DNA-directed RNA polymerase III complex" "IPR007832=RNA polymerase Rpc34, IPR016049=RNA polymerase Rpc34-like" CG5380 16-Dec-15 2015_12 ENSDARG00000012572(polr3f) YNR003C(RPC34) WBGene00021112(W09C3.4) ENSXETG00000024898(polr3f) ENSMUSG00000027427(Polr3f) ENSG00000132664(POLR3F) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0265066 CR44177 http://flybase.net/reports/FBgn0265066.html non_protein_coding_gene CR44177 16-Dec-15 2015_12 FBgn0031171 CG1801 http://flybase.net/reports/FBgn0031171.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR026082=ABC transporter A, ABCA" CG1801 16-Dec-15 2015_12 "YIL013C(PDR11),YOR011W(AUS1),YNR070W(PDR18),YDR011W(SNQ2),YPL058C(PDR12),YOR328W(PDR10),YOR153W(PDR5),YDR406W(PDR15),YOL075C()" viable FBgn0002856 Acp26Ab Accessory gland protein 26Ab http://flybase.net/reports/FBgn0002856.html protein_coding_gene 0005179=hormone activity "0007617=mating behavior, 0018991=oviposition, 0045297=post-mating behavior, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0005576=extracellular region" "accessory protein 26A, CG9024, Accessory gland-specific peptide 26Ab, Acp26a, mst355b, Mst26Ab, Acp, Acp26Aab, msP355b, acp26Ab, Acp26A, mst 355b, Mst26A" IPR008392=Drosophila accessory gland-specific peptide 26Ab CG9024 16-Dec-15 2015_12 " pupal stage && adult stage , adult stage | male " male accessory gland

" adult stage | female , adult stage | male " " adult hemolymph

, male accessory gland

, male accessory gland main cell

, male accessory gland secondary cell

, genital chamber

" viable FBgn0067391 T:Mito-oat Mitochondrial presequence of oat http://flybase.net/reports/FBgn0067391.html engineered_tag "mitochondrial targeting sequence 1, T:mito1" 16-Dec-15 2015_12 FBgn0085768 CR40712 http://flybase.net/reports/FBgn0085768.html FBan0040712 rRNA_gene CR40712 16-Dec-15 2015_12 FBgn0001545 l(1)15Ab lethal (1) 15Ab http://flybase.net/reports/FBgn0001545.html gene "k27e, l(1)k27e" 16-Dec-15 2015_12 lethal FBgn0051510 CG31510 http://flybase.net/reports/FBgn0051510.html "FBgn0039278, FBgn0064125" protein_coding_gene CG10057 "IPR015880=Zinc finger, C2H2-like" CG31510 16-Dec-15 2015_12 viable DRSC14182 E 0.654394879 0.184812793 2.264868038 0.439692902 0.608301879 0.882254829 FBgn0040114 l(2)AR-44 lethal (2) AR-44 http://flybase.net/reports/FBgn0040114.html gene 16-Dec-15 2015_12 lethal FBgn0017414 cag cag http://flybase.net/reports/FBgn0017414.html protein_coding_gene 0003677=DNA binding CG12346 "IPR006600=HTH CenpB-type DNA-binding domain, IPR009057=Homeodomain-like, IPR007889=DNA binding HTH domain, Psq-type" CG12346 16-Dec-15 2015_12 ENSG00000214225 "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0010591 Sply Sphingosine-1-phosphate lyase http://flybase.net/reports/FBgn0010591.html "FBgn0034190, FBgn0044523" protein_coding_gene "0016831=carboxy-lyase activity, 0030170=pyridoxal phosphate binding, 0008117=sphinganine-1-phosphate aldolase activity" "0007527=adult somatic muscle development, 0019752=carboxylic acid metabolic process, 0030149=sphingolipid catabolic process, 0046331=lateral inhibition" 0016021=integral component of membrane "spl, anon-WO0142479.5, sply, Spl, sphingosine-1-phosphate lyase, SPL, sphinganine-1-phosphate lyase, l(2)05091, CG8946" "IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase" CG8946 16-Dec-15 2015_12 ENSDARG00000061375(sgpl1) YDR294C(DPL1) WBGene00006418(tag-38) ENSXETG00000008190(SGPL1) ENSMUSG00000020097(Sgpl1) ENSG00000166224(SGPL1) "lethal,recessive,partially lethal - majority die,flightless,female sterile,partially,male sterile,increased cell death,viable,visible" "dorsal medial muscle,chaeta" FBgn0025519 fidipidine fidipidine http://flybase.net/reports/FBgn0025519.html protein_coding_gene CG7773 IPR019159=Coiled-coil domain of unkwon function DUF2037 CG7773 16-Dec-15 2015_12 ENSDARG00000040678(ccdc93) WBGene00015815(C16A11.2) ENSMUSG00000026339(Ccdc93) ENSG00000125633(CCDC93) "viable,visible" trichogen cell DRSC07618 I -0.172290918 -1.92839258 -0.34420049 -1.074140426 0.081255897 -0.471123804 FBgn0266866 CR45327 http://flybase.net/reports/FBgn0266866.html non_protein_coding_gene CR45327 16-Dec-15 2015_12 FBgn0060603 l(3)S091603 lethal (3) S091603 http://flybase.net/reports/FBgn0060603.html gene 0916/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0031608 CG15435 http://flybase.net/reports/FBgn0031608.html protein_coding_gene 0008270=zinc ion binding 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG15435 16-Dec-15 2015_12 viable FBgn0259452 C211 http://flybase.net/reports/FBgn0259452.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta,ectopic" FBgn0042187 CG17234 http://flybase.net/reports/FBgn0042187.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP113 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG17234 16-Dec-15 2015_12 viable FBgn0031554 CG15418 http://flybase.net/reports/FBgn0031554.html protein_coding_gene "0004867=serine-type endopeptidase inhibitor activity, 0004866=endopeptidase inhibitor activity" "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG15418 16-Dec-15 2015_12 FBgn0021793 l(2)k17026 lethal (2) k17026 http://flybase.net/reports/FBgn0021793.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0046664 anon-38C.35 anon-38C.35 http://flybase.net/reports/FBgn0046664.html gene 38C.35 16-Dec-15 2015_12 FBgn0001473 l(1)9Ec lethal (1) 9Ec http://flybase.net/reports/FBgn0001473.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037551 Gie GTPase indispensable for equal segregation of chromosomes http://flybase.net/reports/FBgn0037551.html FBgn0062457 protein_coding_gene 0005525=GTP binding "0007264=small GTPase mediated signal transduction, 0000819=sister chromatid segregation, 0006886=intracellular protein transport" 0005764=lysosome "novel GTPase indispensable for equal segregation of chromosomes, CG7891, Arl8, BcDNA:LD29185, Q9VHV5" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR024156=Small GTPase superfamily, ARF type, IPR006687=Small GTPase superfamily, SAR1-type, IPR003579=Small GTPase superfamily, Rab type, IPR006689=Small GTPase superfamily, ARF/SAR type" CG7891 16-Dec-15 2015_12 "ENSDARG00000006915(LOC100329405),ENSDARG00000070318(arl8bb)" WBGene00000192(arl-8) "ENSXETG00000022124(arl10c),ENSXETG00000000910(arl10b)" "ENSMUSG00000030105(Arl8b),ENSMUSG00000026426(Arl8a)" "ENSG00000134108(ARL8B),ENSG00000143862(ARL8A)" "partially lethal - majority die,some die during pupal stage" FBgn0004106 Cdk1 Cyclin-dependent kinase 1 http://flybase.net/reports/FBgn0004106.html protein_coding_gene "0004693=cyclin-dependent protein serine/threonine kinase activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0005515=protein binding" "0007283=spermatogenesis, 0007284=spermatogonial cell division, 0006974=cellular response to DNA damage stimulus, 0006468=protein phosphorylation, 0008315=meiotic G2/MI transition, 0048142=germarium-derived cystoblast division, 0007095=mitotic G2 DNA damage checkpoint, 0007141=male meiosis I, 0022008=neurogenesis, 0051726=regulation of cell cycle, 0000278=mitotic cell cycle, 0044818=mitotic G2/M transition checkpoint, 0000086=G2/M transition of mitotic cell cycle, 0070816=phosphorylation of RNA polymerase II C-terminal domain, 0032880=regulation of protein localization, 0000082=G1/S transition of mitotic cell cycle, 0055059=asymmetric neuroblast division, 0007140=male meiosis" "0005875=microtubule associated complex, 0005634=nucleus" "l(2)31Eh, cyclin-dependent kinase, protein 2, CG5363, Cdc2, DmCdc2, CDCDm, CDC2 kinase, Cdc2 kinase, DmCdk1, Cdk1, cdk1, cdc2, Dmcdc2, cdc2 kinase, CDK1, group 4, CDK1/CDC2, cyclin-dependent kinase 1, Dm cdc2, CDC2, 5363, dCdk1, Dcdc2, Cell division control, cdc2Dm, Cdk-1, cyclin dependent kinase, cdc" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG5363 16-Dec-15 2015_12 ENSDARG00000055379 YBR160W(CDC28) WBGene00000405(cdk-1) ENSMUSG00000019942(Cdk1) ENSG00000170312(CDK1) " embryonic stage | early , embryonic stage , adult stage | female " embryonic central nervous system

"lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,recessive,increased cell death,mitotic cell cycle defective,radiation sensitive,heat sensitive,increased cell size,decreased cell number,wild-type,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die during pharate adult stage,size defective,lethal - all die during pupal stage,somatic clone,cell autonomous,cell non-autonomous,female sterile" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,larval outer optic anlage,larval optic anlage,somatic clone,synapse,neuromuscular junction,ganglion mother cell GMC4-2a,wing disc,posterior | third instar larval stage,sensory mother cell | third instar larval stage,type I neuroblast | larval stage,A1-7 dorsal acute muscle 1,ectopic,RP2 motor neuron,embryonic neuroblast,polar body nucleus,spindle,centriole,nuclear pore | heat sensitive,annulate lamellae | heat sensitive,imaginal disc,wing margin,wing disc | third instar larval stage,eye,chromosomepros.PU,embryonic/larval brain,anterior compartment,adult abdomen,heat sensitive,embryonic/larval optic lobe,histoblast & nucleus | conditional ts,tormogen cell,trichogen cell,oocyte,temperature conditional,trichome,chaeta,wing,wing cell,central nervous system,embryonic/larval salivary gland,ganglion mother cell GMC4-2a & spindle,embryonic neuroblast & spindle,secondary spermatogonium,mitotic cell cycle,cyst cell,pole cell,optic lobe,histoblast,wing hair" DRSC03504 IEK -2.679754603 -2.560547216 -1.929005038 -2.429830051 6.678636131 7.757581633 FBgn0259396 C756 http://flybase.net/reports/FBgn0259396.html gene 16-Dec-15 2015_12 visible wing FBgn0037025 Spc105R Spc105-related http://flybase.net/reports/FBgn0037025.html protein_coding_gene "0022008=neurogenesis, 0007052=mitotic spindle organization, 0051382=kinetochore assembly" 0000940=condensed chromosome outer kinetochore "dmKNL-1, dmSpc105R, spc105R, Spc105, DmSpc105, CG11451" CG11451 16-Dec-15 2015_12 "visible,lethal,recessive,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,nucleus,embryonic/larval central nervous system,nucleusri-XT1),spindlemat.ë±Tub67C.THsimVP16,embryonic/larval neuroblast,ganglion mother cell" DRSC11663 IE -3.202282337 -1.70816307 -0.330138905 -3.103978922 0.828515691 0.208099361 FBgn0261453 scaRNA:MeU2-C41 small Cajal body-specific RNA : MeU2-C41 http://flybase.net/reports/FBgn0261453.html snoRNA_gene 0030563=snRNA 2'-O-ribose methylation guide activity 0015030=Cajal body "scaRNA:mgU2-41, mgU2-41, scaRNA:lds-a" CR43570 16-Dec-15 2015_12 FBgn0266595 CR45120 http://flybase.net/reports/FBgn0266595.html non_protein_coding_gene CR45120 16-Dec-15 2015_12 FBgn0005024 depilated depilated http://flybase.net/reports/FBgn0005024.html gene dpt 16-Dec-15 2015_12 "visible,viable" "macrochaeta & adult thorax,macrochaeta & adult head" FBgn0084034 CG41474 http://flybase.net/reports/FBgn0084034.html FBan0041474 protein_coding_gene 16-Dec-15 2015_12 FBgn0069323 X-158-33 X-158-33 http://flybase.net/reports/FBgn0069323.html gene 0007310=oocyte dorsal/ventral axis specification 16-Dec-15 2015_12 "dorsal appendage,germline clone,non-rescuable maternal effect,egg" FBgn0261055 Sfp26Ad Seminal fluid protein 26Ad http://flybase.net/reports/FBgn0261055.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG42603 16-Dec-15 2015_12 FBgn0024618 ms(1)S21 ms(1)S21 http://flybase.net/reports/FBgn0024618.html gene 16-Dec-15 2015_12 male sterile FBgn0010422 TfIIS RNA polymerase II elongation factor http://flybase.net/reports/FBgn0010422.html "FBgn0000474, FBgn0001982" protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" "0032784=regulation of DNA-templated transcription, elongation, 0006357=regulation of transcription from RNA polymerase II promoter, 0006368=transcription elongation from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "l(2)35cF, DmSII, br52, DmS-II, CG3710, transcription cleavage factor IIS, TFIIS, l(2)br52, l(2)35Cf, l35Cf, BG:DS00929.12, TFS-II, lethal(2)35Cf, RnpSII, TFIISA" "IPR003618=Transcription elongation factor S-II, central domain, IPR003617=Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type, IPR016492=Transcription elongation factor, TFIIS-related, IPR017890=Transcription elongation factor S-IIM, IPR017923=Transcription factor IIS, N-terminal, IPR006289=Transcription elongation factor, TFIIS, IPR001222=Zinc finger, TFIIS-type" CG3710 16-Dec-15 2015_12 "ENSDARG00000003531(tcea1),ENSDARG00000012927(tcea2)" YGL043W(DST1) WBGene00012000(T24H10.1) ENSXETG00000008099(tcea1) "ENSMUSG00000033813(Tcea1),ENSMUSG00000059540(Tcea2),ENSMUSG00000001604(Tcea3)" "ENSG00000187735(TCEA1),ENSG00000171703(TCEA2),ENSG00000204219(TCEA3)" "lethal,recessive,viable" wing FBgn0045034 ultA ultrahair A http://flybase.net/reports/FBgn0045034.html FBgn0016074 gene "0035317=imaginal disc-derived wing hair organization, 0008407=chaeta morphogenesis, 0040007=growth" "uhr, ultrahair" 16-Dec-15 2015_12 "wing hair,somatic clone,ectopic,wing,wing margin bristle" FBgn0001780 l(1)M66 lethal (1) M66 http://flybase.net/reports/FBgn0001780.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0052260 CG32260 http://flybase.net/reports/FBgn0052260.html FBgn0064957 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis BcDNA:GH24648 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG32260 16-Dec-15 2015_12 ENSG00000178297(TMPRSS9) viable FBgn0259549 GG01287 http://flybase.net/reports/FBgn0259549.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing" FBgn0022768 Pp2C1 Protein phosphatase 2C http://flybase.net/reports/FBgn0022768.html FBgn0066851 protein_coding_gene "0043169=cation binding, 0016491=oxidoreductase activity, 0004722=protein serine/threonine phosphatase activity" "0055114=oxidation-reduction process, 0006470=protein dephosphorylation" 0005737=cytoplasm "CG2984, anon-WO03040301.132, PP2C, dpp2c1, PP2C1" "IPR003952=Fumarate reductase/succinate dehydrogenase, FAD-binding site, IPR000222=PPM-type phosphatase, divalent cation binding, IPR015655=Protein phosphatase 2C, IPR001932=PPM-type phosphatase domain" CG2984 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0042189 CG17376 http://flybase.net/reports/FBgn0042189.html FBgn0040953 protein_coding_gene 0051536=iron-sulfur cluster binding "CG18461, bs29c06.y1" "IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain" CG17376 16-Dec-15 2015_12 viable FBgn0028587 l(?)AR111 lethal (?) AR111 http://flybase.net/reports/FBgn0028587.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0013517 l(1)XWL lethal (1) XWL http://flybase.net/reports/FBgn0013517.html gene XWL 16-Dec-15 2015_12 FBgn0261670 CG42725 http://flybase.net/reports/FBgn0261670.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260083 2L2181 http://flybase.net/reports/FBgn0260083.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0027780 U26 U26 http://flybase.net/reports/FBgn0027780.html protein_coding_gene 0016878=acid-thiol ligase activity 0006631=fatty acid metabolic process CG13401 "IPR027295=Quinonprotein alcohol dehydrogenase-like domain, IPR018391=Pyrrolo-quinoline quinone beta-propeller repeat, IPR000873=AMP-dependent synthetase/ligase, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG13401 16-Dec-15 2015_12 ENSDARG00000022730(si:dkeyp-117h8.3) WBGene00012356(W09D6.1) ENSXETG00000005614(AASDH) ENSMUSG00000055923(Aasdh) ENSG00000157426(AASDH) viable FBgn0050151 CG30151 http://flybase.net/reports/FBgn0050151.html FBgn0064860 protein_coding_gene BcDNA:RE70748 CG30151 16-Dec-15 2015_12 viable FBgn0039504 CG14260 http://flybase.net/reports/FBgn0039504.html protein_coding_gene 0007527=adult somatic muscle development "IPR000210=BTB/POZ domain, IPR011333=POZ domain" CG14260 16-Dec-15 2015_12 viable "indirect flight muscle,myofibrilMef2.PR" DRSC14755 E 0.634951801 0.607672585 0.839170757 1.558672 1.102049242 -0.667776084 FBgn0038952 CG7069 http://flybase.net/reports/FBgn0038952.html protein_coding_gene "0004743=pyruvate kinase activity, 0030955=potassium ion binding, 0000287=magnesium ion binding" "0006096=glycolytic process, 0006090=pyruvate metabolic process" "0005886=plasma membrane, 0005737=cytoplasm" "IPR015795=Pyruvate kinase, C-terminal, IPR015806=Pyruvate kinase, beta-barrel insert domain, IPR011037=Pyruvate kinase-like, insert domain, IPR018209=Pyruvate kinase, active site, IPR015793=Pyruvate kinase, barrel, IPR015794=Pyruvate kinase, alpha/beta, IPR001697=Pyruvate kinase, IPR015813=Pyruvate/Phosphoenolpyruvate kinase-like domain" CG7069 16-Dec-15 2015_12 viable FBgn0085820 CR41610 http://flybase.net/reports/FBgn0085820.html FBan0041610 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0025938 ci::pan ci::pan http://flybase.net/reports/FBgn0025938.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing margin bristle,wing vein L2,wing vein L3,wing vein L4,wing,anterior" FBgn0031716 CG14015 http://flybase.net/reports/FBgn0031716.html protein_coding_gene "0008496=mannan endo-1,6-alpha-mannosidase activity" IPR026071=Glycosyl hydrolase family 99 CG14015 16-Dec-15 2015_12 "ENSDARG00000001898(manea),ENSDARG00000056450(si:ch211-30b16.2)" "ENSXETG00000011508(MANEAL),ENSXETG00000001060(MANEA)" "ENSMUSG00000042763(Maneal),ENSMUSG00000040520(Manea)" "ENSG00000185090(MANEAL),ENSG00000172469(MANEA)" "viable,visible" trichogen cell FBgn0050222 CG30222 http://flybase.net/reports/FBgn0050222.html "FBgn0034637, FBgn0040656" protein_coding_gene "CG15672, CG12709" CG30222 16-Dec-15 2015_12 viable FBgn0004919 gol goliath http://flybase.net/reports/FBgn0004919.html "FBgn0004375, FBgn0004899" protein_coding_gene "0061630=ubiquitin protein ligase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0005768=endosome "Goliath, meso, g1, anon-G1, Gol, CG2679" "IPR001841=Zinc finger, RING-type, IPR003137=PA domain, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG2679 16-Dec-15 2015_12 "ENSG00000163162(RNF149),ENSG00000170153(RNF150),ENSG00000113269(RNF130),ENSG00000133135(RNF128)" embryonic stage | stage 10-14 " pharyngeal muscle | presumptive

, mesoderm

" viable FBgn0016965 vm2 visible mutation-2 http://flybase.net/reports/FBgn0016965.html gene 16-Dec-15 2015_12 visible wing FBgn0062673 EP2595 EP2595 http://flybase.net/reports/FBgn0062673.html gene EP(2)2595 16-Dec-15 2015_12 FBgn0050496 CG30496 http://flybase.net/reports/FBgn0050496.html "FBgn0062163, FBgn0064856" protein_coding_gene "BcDNA:RE73310, anon-WO0118547.218, CG1952" "IPR013877=YAP-binding/ALF4/Glomulin, IPR019516=Glomulin/ALF4" CG30496 16-Dec-15 2015_12 "ENSDARG00000058267(glmna),ENSDARG00000010958(glmnb)" ENSXETG00000023009(GLMN) ENSMUSG00000029276(Glmn) ENSG00000174842(GLMN) viable FBgn0038979 tHMG2 testis-enriched HMG-box-containing protein 2 http://flybase.net/reports/FBgn0038979.html FBgn0047326 protein_coding_gene "0003677=DNA binding, 0042803=protein homodimerization activity, 0046982=protein heterodimerization activity" "0000785=chromatin, 0005705=polytene chromosome interband, 0005737=cytoplasm, 0005634=nucleus" "CG7046, thmg-2, testis-enriched HMG-box-containing protein-2, tHMG-2, BcDNA:AT28425" IPR009071=High mobility group box domain CG7046 16-Dec-15 2015_12 "YMR072W(ABF2),YPR052C(NHP6A),YBR089C-A(NHP6B)" "ENSXETG00000007910(SOX30),ENSXETG00000023439()" FBgn0032219 CG4995 http://flybase.net/reports/FBgn0032219.html FBgn0032220 protein_coding_gene 0022857=transmembrane transporter activity "0055085=transmembrane transport, 0006839=mitochondrial transport" 0031966=mitochondrial membrane CG18626 "IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain" CG4995 16-Dec-15 2015_12 "ENSDARG00000057352,ENSDARG00000059052" WBGene00008320(C54G10.4) ENSXETG00000002526(SLC25A29) ENSMUSG00000021265(Slc25a29) ENSG00000197119(SLC25A29) viable FBgn0267485 CR45835 http://flybase.net/reports/FBgn0267485.html non_protein_coding_gene CR45835 16-Dec-15 2015_12 FBgn0053735 snmRNA:430:CR33735 snmRNA:430:CR33735 http://flybase.net/reports/FBgn0053735.html non_protein_coding_gene CR33735 CR33735 16-Dec-15 2015_12 FBgn0032867 CG15475 http://flybase.net/reports/FBgn0032867.html protein_coding_gene 38D.19 CG15475 16-Dec-15 2015_12 viable FBgn0001388 l(1)2Bt lethal (1) 2Bt http://flybase.net/reports/FBgn0001388.html gene 16-Dec-15 2015_12 lethal FBgn0004644 hh hedgehog http://flybase.net/reports/FBgn0004644.html "FBgn0000159, FBgn0001191, FBgn0002748, FBgn0002793, FBgn0011486, FBgn0011487, FBgn0044801" protein_coding_gene "0005113=patched binding, 0016015=morphogen activity, 0008233=peptidase activity, 0005515=protein binding, 0004197=cysteine-type endopeptidase activity, 0004175=endopeptidase activity" "0016540=protein autoprocessing, 0007473=wing disc proximal/distal pattern formation, 0042127=regulation of cell proliferation, 0007267=cell-cell signaling, 0035277=spiracle morphogenesis, open tracheal system, 0007478=leg disc morphogenesis, 0007280=pole cell migration, 0007386=compartment pattern specification, 0007487=analia development, 0009880=embryonic pattern specification, 0030713=ovarian follicle cell stalk formation, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0048099=anterior/posterior lineage restriction, imaginal disc, 0006357=regulation of transcription from RNA polymerase II promoter, 0001745=compound eye morphogenesis, 0035289=posterior head segmentation, 0008347=glial cell migration, 0007424=open tracheal system development, 0007346=regulation of mitotic cell cycle, 0035288=anterior head segmentation, 0048103=somatic stem cell division, 0016335=morphogenesis of larval imaginal disc epithelium, 0045880=positive regulation of smoothened signaling pathway, 0016539=intein-mediated protein splicing, 0030908=protein splicing, 0042993=positive regulation of transcription factor import into nucleus, 0045743=positive regulation of fibroblast growth factor receptor signaling pathway, 0048100=wing disc anterior/posterior pattern formation, 0035231=cytoneme assembly, 0007418=ventral midline development, 0007440=foregut morphogenesis, 0035215=genital disc development, 0007446=imaginal disc growth, 0040007=growth, 0007474=imaginal disc-derived wing vein specification, 0031397=negative regulation of protein ubiquitination, 0008595=anterior/posterior axis specification, embryo, 0007224=smoothened signaling pathway, 0007367=segment polarity determination, 0035217=labial disc development, 0035232=germ cell attraction, 0048066=developmental pigmentation, 0007447=imaginal disc pattern formation, 0035290=trunk segmentation, 0042306=regulation of protein import into nucleus, 0002385=mucosal immune response, 0035224=genital disc anterior/posterior pattern formation, 0060914=heart formation, 2000274=regulation of epithelial cell migration, open tracheal system, 0007506=gonadal mesoderm development, 0021960=anterior commissure morphogenesis, 0001751=compound eye photoreceptor cell differentiation, 0007507=heart development, 0045861=negative regulation of proteolysis, 0008544=epidermis development, 0042078=germ-line stem cell division, 0007498=mesoderm development, 0001746=Bolwig's organ morphogenesis, 0046620=regulation of organ growth, 0030707=ovarian follicle cell development, 0007398=ectoderm development, 0007427=epithelial cell migration, open tracheal system, 0007442=hindgut morphogenesis, 0045464=R8 cell fate specification, 0007228=positive regulation of hh target transcription factor activity, 0008354=germ cell migration, 0048592=eye morphogenesis" "0005576=extracellular region, 0005737=cytoplasm, 0005768=endosome, 0016023=cytoplasmic membrane-bounded vesicle, 0005634=nucleus, 0030139=endocytic vesicle, 0005615=extracellular space, 0005886=plasma membrane" "anon-WO0134654.19, Hedghog, l(3)neo57, l(3)neo56, Hedgehog, Mrt, Mir, Hh, hg, l(3)hh, bar-3, Mirabile, CG4637, bar, bar-on-3, HH, Moonrat, bar3, anon-WO0182946.19" "IPR000320=Hedgehog, N-terminal signalling domain, IPR001767=Hedgehog protein, Hint domain, IPR009045=Hedgehog signalling/DD-peptidase zinc-binding domain, IPR003586=Hint domain C-terminal, IPR001657=Hedgehog protein, IPR006141=Intein N-terminal splicing region, IPR028992=Hedgehog/Intein (Hint) domain, IPR003587=Hint domain N-terminal" CG4637 16-Dec-15 2015_12 "ENSDARG00000038867(shhb),ENSDARG00000068567(shha),ENSDARG00000068564,ENSDARG00000058733(ihha),ENSDARG00000058815(ihhb)" "ENSXETG00000011181(DHH),ENSXETG00000013874(IHH)" "ENSMUSG00000023000(Dhh),ENSMUSG00000002633(Shh),ENSMUSG00000006538(Ihh)" "ENSG00000139549(DHH),ENSG00000163501(IHH),ENSG00000164690(SHH)" " embryonic stage , embryonic stage | stage 5 , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , embryonic stage | stage >=5 , embryonic stage | mid , embryonic stage | stage >5 , embryonic stage | stage >=6 , larval stage " " embryonic/larval esophagus

, proctodeum

, embryonic/larval pharynx

, organism | 60-70% egg length

, antennal segment

, maxillary segment

, embryonic/larval foregut

,

segment polarity{ $ nkd* } ,

segment polarity , procephalic segment

, embryonic/larval salivary gland

, organism | 10% egg length

,

10-70% egg length | stripes , intercalary segment

, labial segment

, anal pad

, embryonic/larval hindgut | presumptive

, parasegment 2,4,6,8,10,12,14

{ v wg* } , organism | 90% egg length

, mandibular segment

, embryonic/larval hindgut

, embryonic/larval posterior spiracle

, antennal lobe

, dorsal mesothoracic disc | posterior

, embryonic/larval anterior spiracle

, procephalic segment

{ - ftz- } , labral segment

,

segment polarity{ $ eve* } ,

segment polarity{ $ patch* } " larval stage | third instar stage 2 eye-antennal disc

restricted "lethal,heat sensitive,visible,partially lethal - majority die,dominant,wild-type,recessive,segment polarity phenotype,somatic clone,semidominant,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,paternal effect,cold sensitive,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective,mitotic cell cycle defective,cell migration defective,neuroanatomy defective,increased cell death,increased cell number,size defective" "germarium,egg chamber,germarium region 2a,germarium region 2b,germarium region 3,follicle cell,anterior scutellar bristle,posterior scutellar bristle,,dorsal thick hair,embryonic/first instar larval cuticle,wing,scutellar bristle,trichogen cell,ventral nerve cord commissure,eye,eye disc,male genitalia,anal plate,genital arch,male terminalia sensillum,penis,hypandrial process,basal apodeme of penis,gonopod thorn bristle,gonopod long bristle,ovariole,ommatidium,embryonic/larval epidermis,ommatidial precursor cluster,neuroblast,embryonic head,denticle,embryonic gnathal segment,wing vein,embryonic epidermis,pseudotrachea,cuticle,embryo,ventral double row,dorsal double row,dorsal triple row,medial triple row,ventral triple row,macrochaeta,prescutum,scutum,scutellum,fronto-orbital plate,frons,interfollicle cell,polar follicle cell,oocyte nucleus,oocyte,basal stalk,tergite,leg,ejaculatory bulb apodeme,eye equator,epidermis,embryonic head epidermis,embryonic brain,embryonic optic lobe,adult eye primordium,cardial valve,proventriculus outer layer,embryonic/larval foregut,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,embryonic hindgut,embryonic rectum,embryonic small intestine,embryonic large intestine,embryonic/larval fat body,Bolwig organ,embryonic/larval posterior spiracle,head capsule,embryonic/larval dorsal vessel,abdominal ventral denticle belt,fusome,spectrosome,sternite,oenocyte,muscle attachment site,cephalopharyngeal skeleton,wing margin,wing disc,haltere,antenna,pole cell,tracheal system,imaginal disc,morphogenetic furrow,germline cell,2nd posterior cell,embryonic dorsal epidermis,gastric caecum primordium,genital disc primordium,gonadal sheath proper primordium,fat body/gonad primordium,midline glial cell,presumptive embryonic/larval central nervous system,commissure,mesothoracic tarsal bristle longitudinal row,lamina,embryonic/larval optic stalk,glial cell,1st posterior cell,lamina tangential neuron,lamina intrinsic neuron,unguis,prothoracic leg disc,genital disc,follicle stem cell,ventral thoracic disc,peripodial epithelium,dorsal fine hair,ocellus,ocellar bristle,postvertical bristle,interocellar bristle,embryonic segment,subretinal glial cell,lamina anlage glial cell,eye-antennal disc,abdominal sternite bristle,lateral ocellus,medial ocellus,ventral multidendritic neuron vdaB,ventral midline,visceral mesoderm,abdominal tracheal pit,metathoracic tracheal pit,embryonic/larval tracheal system,embryonic/larval dorsal branch,embryonic/larval visceral branch,embryonic/larval dorsal trunk,lateral trunk anterior branch,ectoderm,cardioblast,antennal sense organ,gonad,anterior crossvein,embryonic ventral epidermis,embryonic/larval cuticle,female genital disc,male genital disc,female genitalia,C-734,sensory mother cell,en-e16E,dorsal double row | pharate adult stage,ventral double row | pharate adult stage,dorsal triple row | pharate adult stage,medial triple row | pharate adult stage,ventral triple row | pharate adult stage,wing | pharate adult stage,embryonic abdomen,germline cell |,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,MP1 neuron,VUM neuron,lateral trunk posterior branch,prd.RG1,interommatidial bristle,retina,anterior commissure,wing disc anterior compartment |,tracheal tip cell,embryonic/larval ganglionic branch,costal cell,mesothoracic tergum,wing blade" FBgn0001476 l(1)9Fb lethal (1) 9Fb http://flybase.net/reports/FBgn0001476.html gene 16-Dec-15 2015_12 lethal FBgn0260398 Pbp49 PSEA-binding protein 49kD http://flybase.net/reports/FBgn0260398.html "FBgn0033267, FBgn0022383, FBgn0260389" protein_coding_gene "0003681=bent DNA binding, 0005515=protein binding, 0043565=sequence-specific DNA binding, 0003677=DNA binding" "0042796=snRNA transcription from RNA polymerase III promoter, 0042795=snRNA transcription from RNA polymerase II promoter, 0065004=protein-DNA complex assembly" 0019185=snRNA-activating protein complex "PSEA-binding protein of 49 kDa, snRNA activator protein 50, Drosophila melanogaster PSE-binding protein 49-kDa subunit, Proximal Sequence Element-Binding Protein 49, DmSNAP50, CG11508, CG42515, PSEA-binding protein, DmPBP49, DMPBP49, Dromel_CG11508_FBtr0088817_mORF, DmSNAPc, DmPBP" "IPR022042=snRNA-activating protein complex, subunit 3" CG42515 16-Dec-15 2015_12 FBgn0036178 CG14137 http://flybase.net/reports/FBgn0036178.html protein_coding_gene CG14137 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0262741 MRE23 mRNA-like ncRNA in embryogenesis 23 http://flybase.net/reports/FBgn0262741.html "FBgn0086554, FBgn0262589" non_protein_coding_gene CR43126 CR43126 16-Dec-15 2015_12 FBgn0060500 l(3)S106713 lethal (3) S106713 http://flybase.net/reports/FBgn0060500.html gene 1067/13 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0003325 Scotched-eye Scotched eye http://flybase.net/reports/FBgn0003325.html gene Sc 16-Dec-15 2015_12 "viable,female,female fertile,lethal,recessive,visible,dominant,reduced" "ommatidium,eye,abdomen,female" FBgn0005327 Pale Pale http://flybase.net/reports/FBgn0005327.html gene P 16-Dec-15 2015_12 "lethal,recessive" FBgn0038395 CG10407 http://flybase.net/reports/FBgn0038395.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space cg10407 IPR010562=Haemolymph juvenile hormone binding CG10407 16-Dec-15 2015_12 viable FBgn0031736 CG11030 http://flybase.net/reports/FBgn0031736.html protein_coding_gene "0005730=nucleolus, 0005654=nucleoplasm" IPR007146=Sas10/Utp3/C1D CG11030 16-Dec-15 2015_12 ENSDARG00000045372(ngdn) YER127W(LCP5) WBGene00003059(lpd-2) ENSXETG00000014562(BC064878.1) ENSMUSG00000022204(Ngdn) ENSG00000129460(NGDN) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02120 EK 1.380869704 1.33356492 2.119776056 -1.432372991 1.603420862 0.773291202 FBgn0002760 mit(1)10 mitotic 10 http://flybase.net/reports/FBgn0002760.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0044091 E(rst)D25 E(rst)D25 http://flybase.net/reports/FBgn0044091.html gene 0001745=compound eye morphogenesis D25 16-Dec-15 2015_12 FBgn0021931 l(2)k11021 lethal (2) k11021 http://flybase.net/reports/FBgn0021931.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085530 CG40871 http://flybase.net/reports/FBgn0085530.html FBan0040871 protein_coding_gene 16-Dec-15 2015_12 FBgn0267187 CR45627 http://flybase.net/reports/FBgn0267187.html non_protein_coding_gene CR45627 16-Dec-15 2015_12 FBgn0036056 CG6709 http://flybase.net/reports/FBgn0036056.html protein_coding_gene CG6709 16-Dec-15 2015_12 "viable,fertile" FBgn0028228 l(3)S005028 lethal (3) S005028 http://flybase.net/reports/FBgn0028228.html gene l(3)S127405 16-Dec-15 2015_12 "lethal,recessive" FBgn0013586 l(3)97Da lethal (3) 97Da http://flybase.net/reports/FBgn0013586.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0037611 CG11755 http://flybase.net/reports/FBgn0037611.html protein_coding_gene "IPR018785=Cysteine-rich domain, DPF-motif" CG11755 16-Dec-15 2015_12 ENSDARG00000045551(si:ch211-239e6.4) ENSMUSG00000064284(2210021J22Rik) viable FBgn0037228 CG1092 http://flybase.net/reports/FBgn0037228.html FBan0001092 protein_coding_gene 0022008=neurogenesis CG1092 16-Dec-15 2015_12 "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0027149 l(3)71CDa lethal (3) 71CDa http://flybase.net/reports/FBgn0027149.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044105 E(rst)C41 E(rst)C41 http://flybase.net/reports/FBgn0044105.html gene 0001745=compound eye morphogenesis C41 16-Dec-15 2015_12 viable "eye,cone cell" FBgn0011206 bol boule http://flybase.net/reports/FBgn0011206.html "FBgn0040826, FBgn0063736" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding" "0045836=positive regulation of meiotic nuclear division, 0006417=regulation of translation, 0007283=spermatogenesis, 0008315=meiotic G2/MI transition, 0048137=spermatocyte division, 0007140=male meiosis, 0046331=lateral inhibition, 0007476=imaginal disc-derived wing morphogenesis" "0005737=cytoplasm, 0005634=nucleus, 0043204=perikaryon" "BcDNA:AT13332, ms(3)07272, CG4727, BOL, Bol, lincRNA.485, CG4760, Boule" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG4760 16-Dec-15 2015_12 ENSDARG00000036214(dazl) ENSXETG00000025199(dazl) ENSMUSG00000025977 ENSG00000152430(BOLL) " spermatogenesis && adult stage , larval stage&&pupal stage " testis

"meiotic cell cycle defective,male,male sterile,recessive,viable,fertile,visible" "Kenyon cell | pupal stage,gamma Kenyon cell | pupal stage,spindle | male,testis,Nebenkern,primary spermatocyte cyst,germline cell,male,eye,wing,posterior compartment,spermatozoon,spermatid,chaeta" FBgn0053547 Rim Rab3 interacting molecule http://flybase.net/reports/FBgn0053547.html "FBgn0038556, FBgn0038557, FBgn0038559, FBtr0083520, FBpp0082944, FBtr0083521, FBpp0082945" protein_coding_gene "0017137=Rab GTPase binding, 0030695=GTPase regulator activity" "0016079=synaptic vesicle exocytosis, 0048167=regulation of synaptic plasticity, 0017157=regulation of exocytosis, 0007269=neurotransmitter secretion, 0007274=neuromuscular synaptic transmission, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0070073=clustering of voltage-gated calcium channels" "0048786=presynaptic active zone, 0008021=synaptic vesicle" "Rim, CG7305, dm-Rim, CG7301, RIM, UNC-10/RIM, DmRIM, CG33547, CG7321" "IPR010911=Rab-binding domain, IPR001478=PDZ domain, IPR000008=C2 domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG33547 16-Dec-15 2015_12 WBGene00006750(unc-10) "ENSXETG00000002308(RIMS1),ENSXETG00000004073()" "ENSMUSG00000037386(Rims2),ENSMUSG00000041670" "ENSG00000079841(RIMS1),ENSG00000176406(RIMS2)" "viable,fertile,neurophysiology defective" DRSC16227 I -1.693069091 0.274729917 -0.226377861 0.514883545 0.369804269 -0.793992979 FBgn0030697 CG8565 http://flybase.net/reports/FBgn0030697.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "0005737=cytoplasm, 0005634=nucleus" SPRK2 "IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG8565 16-Dec-15 2015_12 FBgn0052828 CG32828 http://flybase.net/reports/FBgn0052828.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028532 CG7968 http://flybase.net/reports/FBgn0028532.html FBgn0027848 protein_coding_gene "BG:DS00941.15, DS00941.15" IPR010562=Haemolymph juvenile hormone binding CG7968 16-Dec-15 2015_12 viable FBgn0060449 l(3)S120710 lethal (3) S120710 http://flybase.net/reports/FBgn0060449.html gene 1207/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0265880 CR44669 http://flybase.net/reports/FBgn0265880.html non_protein_coding_gene lincRNA.597 CR44669 16-Dec-15 2015_12 FBgn0265858 CR44647 http://flybase.net/reports/FBgn0265858.html non_protein_coding_gene CR44647 16-Dec-15 2015_12 FBgn0014906 Hydr2 ë±/ë_ hydrolase2 http://flybase.net/reports/FBgn0014906.html protein_coding_gene 0016298=lipase activity "0022416=chaeta development, 0035220=wing disc development, 0006629=lipid metabolic process" "unnamed, CT11757, DMU29170, anon-23Da, anon-23D, C24, alpha/beta hydrolase2, c24, HYDR2, cg3488, CG3488" "IPR012020=AB-hydrolase ABHD1/2/3, IPR000073=Alpha/beta hydrolase fold-1, IPR000952=Uncharacterised protein family UPF0017, hydrolase-like, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG3488 16-Dec-15 2015_12 ENSDARG00000045804(abhd2b) ENSXETG00000017771(ABHD2) ENSMUSG00000039202(Abhd2) ENSG00000140526(ABHD2) viable FBgn0260301 GSd207 http://flybase.net/reports/FBgn0260301.html gene 16-Dec-15 2015_12 lethal FBgn0037788 CG3940 http://flybase.net/reports/FBgn0037788.html protein_coding_gene "0008270=zinc ion binding, 0004089=carbonate dehydratase activity" 0006730=one-carbon metabolic process "IPR023561=Carbonic anhydrase, alpha-class, IPR018338=Carbonic anhydrase, alpha-class, conserved site, IPR001148=Alpha carbonic anhydrase" CG3940 16-Dec-15 2015_12 "viable,fertile" FBgn0264962 Pcf11 Protein 1 of cleavage and polyadenylation factor 1 http://flybase.net/reports/FBgn0264962.html "FBgn0004398, FBgn0022063, FBgn0033975, FBgn0062215" protein_coding_gene 0003723=RNA binding "0022008=neurogenesis, 0006379=mRNA cleavage" 0005849=mRNA cleavage factor complex "Inverse regulator a, Pcf11, lethal (2) k08015, CG10228, l(2)k08015, Inr-a, dPcf11, pcf11, anon-WO0118547.146" "IPR008942=ENTH/VHS, IPR006569=CID domain, IPR006903=RNA polymerase II-binding domain" CG10228 16-Dec-15 2015_12 ENSDARG00000044625(pcf11) WBGene00020092(pcf-11) ENSMUSG00000041328(Pcf11) ENSG00000165494(PCF11) FBgn0032495 CG16820 http://flybase.net/reports/FBgn0032495.html protein_coding_gene 0005615=extracellular space cg16820 IPR010562=Haemolymph juvenile hormone binding CG16820 16-Dec-15 2015_12 "viable,visible" "trichogen cell,tormogen cell" FBgn0264399 FCG-A http://flybase.net/reports/FBgn0264399.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0033075 Pld Phospholipase D http://flybase.net/reports/FBgn0033075.html protein_coding_gene "0004630=phospholipase D activity, 0035091=phosphatidylinositol binding" "0050764=regulation of phagocytosis, 0007602=phototransduction, 0007349=cellularization, 0048215=positive regulation of Golgi vesicle fusion to target membrane, 0048017=inositol lipid-mediated signaling, 0007030=Golgi organization, 0006654=phosphatidic acid biosynthetic process, 0010004=gastrulation involving germ band extension, 0030334=regulation of cell migration" 0031410=cytoplasmic vesicle "pld1, PLD, CG12110, mitochondrial phospholipase, dPld, pld, phospholipase D, mitoPLD, dPLD" "IPR016555=Phospholipase D1/D2, IPR015679=Phospholipase D family, IPR001736=Phospholipase D/Transphosphatidylase, IPR025202=Phospholipase D-like domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001683=Phox homologous domain" CG12110 16-Dec-15 2015_12 "ENSDARG00000056191,ENSDARG00000056228(pld1a),ENSDARG00000057125,ENSDARG00000034262(pld2)" YKR031C(SPO14) WBGene00004040(pld-1) "ENSXETG00000021019(PLD2),ENSXETG00000009136(PLD1)" "ENSMUSG00000020828(Pld2),ENSMUSG00000027695(Pld1)" "ENSG00000129219(PLD2),ENSG00000075651(PLD1)" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,maternal effect,developmental rate defective,neurophysiology defective" "eye photoreceptor cell,rhabdomereGMR.PF,retina,rhabdomereninaE.PD,ommatidium,gastrula embryo,blastoderm embryo,pre-blastoderm embryo,Golgi-associated vesicle" FBgn0067730 l(3)F6 lethal (3) F6 http://flybase.net/reports/FBgn0067730.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265366 CR44307 http://flybase.net/reports/FBgn0265366.html non_protein_coding_gene CR44307 16-Dec-15 2015_12 FBgn0011801 l(3)rL061 lethal (3) rL061 http://flybase.net/reports/FBgn0011801.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0053970 CG33970 http://flybase.net/reports/FBgn0053970.html "FBgn0039422, FBgn0039423, FBgn0040604, FBgn0051085, FBtr0084993, FBpp0084366, FBtr0085004, FBpp0084376, FBtr0085005, FBpp0084377" protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "CG31085, CG6162, CG14559, CG6166" "IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013525=ABC-2 type transporter, IPR000412=ABC-2 transporter, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain" CG33970 16-Dec-15 2015_12 ENSDARG00000071341 lethal FBgn0044014 Smac49a Smac49a http://flybase.net/reports/FBgn0044014.html gene 16-Dec-15 2015_12 FBgn0038190 CG9926 http://flybase.net/reports/FBgn0038190.html protein_coding_gene IPR000313=PWWP domain CG9926 16-Dec-15 2015_12 "ENSDARG00000019530(hdgfrp2),ENSDARG00000019045(wu:fc32f04)" "ENSG00000166503(HDGFRP3),ENSG00000143321(HDGF),ENSG00000112273(HDGFL1)" FBgn0265205 CR44265 http://flybase.net/reports/FBgn0265205.html non_protein_coding_gene CR44265 16-Dec-15 2015_12 FBgn0010374 uni unicorn http://flybase.net/reports/FBgn0010374.html gene 16-Dec-15 2015_12 "female sterile,male fertile" FBgn0051111 CG31111 http://flybase.net/reports/FBgn0051111.html FBgn0039267 protein_coding_gene 0022008=neurogenesis 0005634=nucleus CG13649 "IPR003888=FY-rich, N-terminal, IPR003889=FY-rich, C-terminal" CG31111 16-Dec-15 2015_12 ENSXETG00000009190(BC081351.1) ENSMUSG00000011114(Tbrg1) ENSG00000154144(TBRG1) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC14649 I -1.504314781 -0.39908959 0.737323531 -1.198998126 1.13947958 0.200354411 FBgn0052642 CG32642 http://flybase.net/reports/FBgn0052642.html protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion CG32642 16-Dec-15 2015_12 FBgn0003514 sqh spaghetti squash http://flybase.net/reports/FBgn0003514.html protein_coding_gene "0005509=calcium ion binding, 0032036=myosin heavy chain binding" "0007298=border follicle cell migration, 0042060=wound healing, 0035159=regulation of tube length, open tracheal system, 0035148=tube formation, 0090254=cell elongation involved in imaginal disc-derived wing morphogenesis, 0030048=actin filament-based movement, 0060288=formation of a compartment boundary, 0035191=nuclear axial expansion, 0022008=neurogenesis, 0030707=ovarian follicle cell development, 0032956=regulation of actin cytoskeleton organization, 0019749=cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte, 0000281=mitotic cytokinesis, 0007300=ovarian nurse cell to oocyte transport, 0001736=establishment of planar polarity, 0035317=imaginal disc-derived wing hair organization, 0035277=spiracle morphogenesis, open tracheal system, 0031036=myosin II filament assembly, 0003384=apical constriction involved in gastrulation" "0035183=female germline ring canal inner rim, 0016460=myosin II complex, 0032154=cleavage furrow, 0031941=filamentous actin, 0005938=cell cortex, 0005886=plasma membrane, 0051233=spindle midzone, 0030496=midbody, 0045177=apical part of cell, 0005912=adherens junction, 0016324=apical plasma membrane, 0005737=cytoplasm, 0005911=cell-cell junction, 0016461=unconventional myosin complex, 0048471=perinuclear region of cytoplasm" "MLC, Spaghetti squash, Myosin II, myosin, regulatory light chain of nonmuscle myosin-II, spaghetti-squash, MyoII regulatory light chain, Myosin LC, RLC, MLRC, RMLC, regulatory light chain of nonmuscle myosin II, Squash, Myo-II regulatory light chain, regulatory light chain of Myosin II, light chain of nonmuscle Myosin II, regulatory light chain of myosin, nonmuscle myosin II, non-muscle myosin II regulatory light chain, myosinII, myosin II regulatory light chain, MyosinII, Sqh, myosin 2, Spaghetti Squash, Myo II, Myosin regulatory light chain, Myosin Regulatory Light Chain, ssq, DmMRLC_C, Myosin, non-muscle Myosin II, NMM, myosin II, spg, regulatory light chain, Myo, myosin-II light chain, Spaghetti-Squash, phospho-Myosin light chain 2, Myo-II, regulatory myosin light chain, Spaghetti-squash, myoII, Myosin-II, Myo-II RLC, squ, nonmuscle myosin II regulatory light chain, myosin light chain, CG3595, myosin regulatory light chain, Myosin light chain, type II myosin regulatory light chain, MRLC, MyoII, Myosin-II light chain, myo-II regulatory light chain, non-muscle myosin II, sgh, Myosin II regulatory light chain" "IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG3595 16-Dec-15 2015_12 "ENSDARG00000008030,ENSDARG00000025326(myl12.2),ENSDARG00000014433(myl9l),ENSDARG00000038123(zgc:103467)" WBGene00003372(mlc-4) ENSXETG00000025009(mrlc2) "ENSMUSG00000067818,ENSMUSG00000024048(2900073G15Rik),ENSMUSG00000034868(Myl12b)" "ENSG00000118680(MYL12B),ENSG00000101608(MYL12A),ENSG00000101335(MYL9)" "short lived,calorie restriction conditional,cytokinesis defective,wound healing defective,recessive,cell migration defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,maternal effect,partially lethal - majority die,wild-type,neuroanatomy defective,somatic clone,cell shape defective,axis specification defective,male limited,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective" "eye disc,somatic clone,wing disc | third instar larval stage,wing disc,somatic clone | third instar larval stage,furrow canal,posterior,nucleus | embryonic stage 4,oocyte,germline clone,nurse cell,egg,posterior spiracle primordium,morphogenetic furrow,organism | embryonic stage,embryo,eye,leg,distal,embryonic segment,ventral thoracic disc,wing,ovary,border follicle cell,centripetally migrating follicle cell,dorsal appendage,interfollicle cell,actomyosin contractile ring,mitotic telophase,mitotic telophase & spindle,egg chamber,nurse cell ring canal,extended germ band embryo,epidermis,hub cell,embryonic/larval dorsal trunk,epithelium,follicle cell,anterior embryonic/larval midgut,male limited,embryonic proventriculus,adult brain,mitochondrion,adult mushroom body,cystocyte,cephalopharyngeal skeleton,denticle belt,S2 cell-line & spindle microtubule,S2 cell-line & cell,S2 cell-line & spindle,embryonic/larval neuroblast,ganglion mother cell" FBgn0061495 l(2)45As lethal (2) 45As http://flybase.net/reports/FBgn0061495.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014366 noi noisette http://flybase.net/reports/FBgn0014366.html FBgn0011357 protein_coding_gene "0044822=poly(A) RNA binding, 0008270=zinc ion binding" "0000398=mRNA splicing, via spliceosome, 0009566=fertilization, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0051726=regulation of cell cycle, 0051533=positive regulation of NFAT protein import into nucleus" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005686=U2 snRNP, 0005681=spliceosomal complex" "Noisette, SF3a[60], l(3)j3E7, ms3225, U2, SF3A3, Noi, CG2925" "IPR000690=Zinc finger, C2H2-type matrin, IPR021966=Splicing factor SF3a60 binding domain, IPR015880=Zinc finger, C2H2-like, IPR024598=Domain of unknown function DUF3449" CG2925 16-Dec-15 2015_12 ENSDARG00000056447(sf3a3) YDL030W(PRP9) WBGene00011758(T13H5.4) ENSXETG00000022923(SF3A3) ENSMUSG00000028902(Sf3a3) ENSG00000183431(SF3A3) "lethal,recessive,male sterile,viable,male,female,female sterile,cold sensitive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type" "germline cell,male,nurse cell,nurse cell & nucleus,oocyte nucleus,dorsal appendage,egg,head & macrochaeta | dorsal,thorax & macrochaeta | dorsal,sex comb,medial triple row" DRSC12383 IK 1.715278791 1.043307159 -0.391640131 -1.024353493 -1.749097176 -0.448378309 FBgn0039679 ppk19 pickpocket 19 http://flybase.net/reports/FBgn0039679.html protein_coding_gene 0005272=sodium channel activity "0006814=sodium ion transport, 0050914=sensory perception of salty taste" 0016021=integral component of membrane "PPK19, CG18287, Pickpocket19" "IPR001873=Na+ channel, amiloride-sensitive" CG18287 16-Dec-15 2015_12 "taste perception defective,viable" FBgn0266311 CR44976 http://flybase.net/reports/FBgn0266311.html non_protein_coding_gene CR44976 16-Dec-15 2015_12 FBgn0052037 CG32037 http://flybase.net/reports/FBgn0052037.html FBgn0036006 protein_coding_gene CG3426 CG32037 16-Dec-15 2015_12 FBgn0040811 CG13479 http://flybase.net/reports/FBgn0040811.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028479 Mtpë± Mitochondrial trifunctional protein ë± subunit http://flybase.net/reports/FBgn0028479.html protein_coding_gene "0004300=enoyl-CoA hydratase activity, 0016509=long-chain-3-hydroxyacyl-CoA dehydrogenase activity" "0006635=fatty acid beta-oxidation, 0042594=response to starvation, 0042060=wound healing, 0008340=determination of adult lifespan" "0005811=lipid particle, 0005739=mitochondrion, 0016507=mitochondrial fatty acid beta-oxidation multienzyme complex, 0005777=peroxisome, 0005875=microtubule associated complex" "BcDNA:GH12558, CG4389, Mtpalpha, CG 4389" "IPR016040=NAD(P)-binding domain, IPR018376=Enoyl-CoA hydratase/isomerase, conserved site, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily, IPR012803=Fatty acid oxidation complex, alpha subunit, mitochondrial, IPR006176=3-hydroxyacyl-CoA dehydrogenase, NAD binding, IPR006108=3-hydroxyacyl-CoA dehydrogenase, C-terminal" CG4389 16-Dec-15 2015_12 "ENSDARG00000060594(zgc:158138),ENSDARG00000057128(hadha)" "WBGene00020347(T08B2.7),WBGene00001150(ech-1)" ENSXETG00000026457(hadha) ENSMUSG00000025745(Hadha) ENSG00000084754(HADHA) "viable,fertile,short lived,locomotor behavior defective,starvation stress response defective" "adult fat body,lipid particle" FBgn0003476 Spl Splayed http://flybase.net/reports/FBgn0003476.html FBgn0005223 gene "lethal Elaine Tasaka 23, l(3)ET23" 16-Dec-15 2015_12 "lethal,heat sensitive" "leg,joint" FBgn0020863 chianti chianti http://flybase.net/reports/FBgn0020863.html gene chi 16-Dec-15 2015_12 eye color defective pigment cell FBgn0016689 Oab Orientation abnormal http://flybase.net/reports/FBgn0016689.html gene 0001654=eye development 16-Dec-15 2015_12 "lethal,recessive" ommatidium FBgn0084644 2.15.50 2.15.50 http://flybase.net/reports/FBgn0084644.html gene 16-Dec-15 2015_12 "visible,eye color defective" "pigment cell,eye" FBgn0022709 Adk1 Adenylate kinase 1 http://flybase.net/reports/FBgn0022709.html FBgn0036265 protein_coding_gene "0004017=adenylate kinase activity, 0005524=ATP binding, 0009041=uridylate kinase activity" "0046034=ATP metabolic process, 0006139=nucleobase-containing compound metabolic process, 0006207='de novo' pyrimidine nucleobase biosynthetic process" "0005737=cytoplasm, 0005634=nucleus" "AK1, DAK1, CG17146, adk1, ADK-1, Dak1, bs34e10.y1, Adenylate kinase-1" "IPR000850=Adenylate kinase/UMP-CMP kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006267=Adenylate kinase, isozyme 1/5" CG17146 16-Dec-15 2015_12 ENSDARG00000001950(zgc:91930) WBGene00009531(F38B2.4) ENSXETG00000021999(ak1) ENSMUSG00000026817(Ak1) ENSG00000106992(AK1) viable FBgn0017403 eddy eddy http://flybase.net/reports/FBgn0017403.html gene 0007409=axonogenesis 16-Dec-15 2015_12 "viable,female fertile,male fertile" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor" FBgn0041836 Eth-AR209 Eth-AR209 http://flybase.net/reports/FBgn0041836.html gene Eth[AR]209 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0265534 CR44384 http://flybase.net/reports/FBgn0265534.html non_protein_coding_gene CR44384 16-Dec-15 2015_12 FBgn0267201 CR45641 http://flybase.net/reports/FBgn0267201.html non_protein_coding_gene CR45641 16-Dec-15 2015_12 FBgn0005652 Mst59Db Male-specific transcript 59Db http://flybase.net/reports/FBgn0005652.html gene 16-Dec-15 2015_12 FBgn0000078 Amy-d Amylase distal http://flybase.net/reports/FBgn0000078.html FBgn0014456 protein_coding_gene "0004556=alpha-amylase activity, 0005509=calcium ion binding, 0043169=cation binding" 0005975=carbohydrate metabolic process "AMY, Amy1, Amy-distal, AmyB, alpha-Amylase, AmyD, alpha-amylase, amy, amyB(3), Amy6, Amylase, Amy3, amy-d, CG17876, alpha-amylase distal, Amy, Amy(d), amylase, alphaAmy, alpha-AMY, Amylase-B" "IPR031319=Alpha-amylase, C-terminal domain, IPR006046=Alpha amylase, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR013781=Glycoside hydrolase, catalytic domain, IPR006048=Alpha-amylase/branching enzyme, C-terminal all beta, IPR015902=Glycoside hydrolase, family 13, IPR017853=Glycoside hydrolase superfamily, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain" CG17876 16-Dec-15 2015_12 "ENSDARG00000013856(amy2a),ENSDARG00000030357(zgc:66313),ENSDARG00000009443(zgc:92137)" WBGene00008220(C50B6.7) "ENSXETG00000010847(),ENSXETG00000010846(amy1a)" "ENSMUSG00000074266(Amy2a3),ENSMUSG00000074268(Amy2a5),ENSMUSG00000079850,ENSMUSG00000074267(Amy2a4),ENSMUSG00000074264(Amy1)" "ENSG00000197839,ENSG00000196318,ENSG00000174876(AMY1B),ENSG00000051415,ENSG00000187733(AMY1C)" adult stage adult midgut

adult stage " midgut

{ - mapP00 } , adult midgut

, midgut

" electrophoretic variant FBgn0024240 eel eel http://flybase.net/reports/FBgn0024240.html gene "0030727=germarium-derived female germ-line cyst formation, 0030718=germ-line stem cell maintenance" 16-Dec-15 2015_12 FBgn0038252 BigH1 Histone H1 variant BigH1 http://flybase.net/reports/FBgn0038252.html protein_coding_gene 0003677=DNA binding "0060303=regulation of nucleosome density, 0006355=regulation of transcription, DNA-templated, 0006334=nucleosome assembly" "0000786=nucleosome, 0000785=chromatin, 0005634=nucleus" "CG3509, dBigH1" "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain" CG3509 16-Dec-15 2015_12 "lethal - all die during embryonic stage,viable" FBgn0001002 Fs(2)Tld Female sterile (2) Told http://flybase.net/reports/FBgn0001002.html gene "Told, Fs(2)Sz11" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant,female sterile soma-dependent" embryonic head FBgn0013459 fs(2)neo9 fs(2)neo9 http://flybase.net/reports/FBgn0013459.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0000528 E81 E81 http://flybase.net/reports/FBgn0000528.html gene 0006357=regulation of transcription from RNA polymerase II promoter 0005634=nucleus 16-Dec-15 2015_12 FBgn0041835 Eth-AR217 Eth-AR217 http://flybase.net/reports/FBgn0041835.html gene Eth[AR]217 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0265374 CR44315 http://flybase.net/reports/FBgn0265374.html non_protein_coding_gene CR44315 16-Dec-15 2015_12 FBgn0050278 CG30278 http://flybase.net/reports/FBgn0050278.html FBgn0034714 protein_coding_gene CG3387 CG30278 16-Dec-15 2015_12 viable DRSC22787 E -0.807424664 -0.669509457 -1.844067628 -1.256954094 -0.283834291 -1.209626107 FBgn0262880 CG43235 http://flybase.net/reports/FBgn0262880.html protein_coding_gene 0004180=carboxypeptidase activity 0006508=proteolysis "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide" CG43235 16-Dec-15 2015_12 FBgn0002101 l(2)57Db lethal (2) 57Db http://flybase.net/reports/FBgn0002101.html gene l(2)57CDc 16-Dec-15 2015_12 lethal FBgn0037679 CG8866 http://flybase.net/reports/FBgn0037679.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" 0006468=protein phosphorylation 0005737=cytoplasm "dULK3, UNC 51-like" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR007330=MIT, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG8866 16-Dec-15 2015_12 ENSXETG00000021133(ULK3) ENSMUSG00000032308(Ulk3) FBgn0058234 CG40234 http://flybase.net/reports/FBgn0058234.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263835 CR43697 http://flybase.net/reports/FBgn0263835.html pseudogene_attribute CR43697 16-Dec-15 2015_12 FBgn0010138 l(2)DTS100 lethal (2) DTS100 http://flybase.net/reports/FBgn0010138.html gene DTS100 16-Dec-15 2015_12 "lethal,heat sensitive,dominant" FBgn0025517 fs(3)82CDa fs(3)82CDa http://flybase.net/reports/FBgn0025517.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0041766 anon-d44 anon-d44 http://flybase.net/reports/FBgn0041766.html gene d44 16-Dec-15 2015_12 FBgn0005341 rlu rolled up http://flybase.net/reports/FBgn0005341.html gene 16-Dec-15 2015_12 "viable,fertile" wing FBgn0016812 l(1)L13 lethal (1) L13 http://flybase.net/reports/FBgn0016812.html gene L13 16-Dec-15 2015_12 "lethal,recessive" FBgn0266837 CR45299 http://flybase.net/reports/FBgn0266837.html non_protein_coding_gene CR45299 16-Dec-15 2015_12 FBgn0014196 l(1)14Cc lethal (1) 14Cc http://flybase.net/reports/FBgn0014196.html gene l(1)14Cd 16-Dec-15 2015_12 "lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage" FBgn0000787 fs(1)C3 female sterile (1) C3 http://flybase.net/reports/FBgn0000787.html gene 16-Dec-15 2015_12 female sterile "chorion,dorsal appendage" FBgn0035823 eIF4E-5 eIF4E-5 http://flybase.net/reports/FBgn0035823.html protein_coding_gene "0000339=RNA cap binding, 0005515=protein binding, 0003743=translation initiation factor activity, 0031370=eukaryotic initiation factor 4G binding, 0000340=RNA 7-methylguanosine cap binding" "0006413=translational initiation, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" 0016281=eukaryotic translation initiation factor 4F complex "CG8277, eIF4E, CT24507" "IPR023398=Translation Initiation factor eIF- 4e-like, IPR001040=Translation Initiation factor eIF- 4e, IPR019770=Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG8277 16-Dec-15 2015_12 "ENSDARG00000013274(zgc:101581),ENSDARG00000012274(zgc:110154),ENSDARG00000014565(eif4e1b)" YOL139C(CDC33) WBGene00002061(ife-3) ENSMUSG00000028156(Eif4e) "ENSG00000151247(EIF4E),ENSG00000175766(EIF4E1B)" viable DRSC10975 E 0.078089297 -0.02156391 -1.654618156 -0.233629184 0.020744333 -0.798609818 FBgn0064173 l(2)T76 lethal (2) T76 http://flybase.net/reports/FBgn0064173.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0267440 CR45790 http://flybase.net/reports/FBgn0267440.html non_protein_coding_gene CR45790 16-Dec-15 2015_12 FBgn0000999 Fs(2)Tar Female sterile (2) Tarhos http://flybase.net/reports/FBgn0000999.html gene "Tar, Fs(2)Sz9, Tarhos" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant" "embryo,cleavage nucleus" FBgn0032582 CG13258 http://flybase.net/reports/FBgn0032582.html protein_coding_gene CG13258 16-Dec-15 2015_12 "viable,fertile" FBgn0002473 l(3)SG28 lethal (3) SG28 http://flybase.net/reports/FBgn0002473.html gene "l(3)8m-12, SG28" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle,mitosis & nuclear chromosome,mitotic cell cycle" FBgn0040233 cana CENP-ana http://flybase.net/reports/FBgn0040233.html "FBgn0022074, FBgn0032356, FBgn0052955, FBgn0053694" protein_coding_gene "0008017=microtubule binding, 0003777=microtubule motor activity, 0005524=ATP binding, 0008574=ATP-dependent microtubule motor activity, plus-end-directed" "0007018=microtubule-based movement, 0007091=metaphase/anaphase transition of mitotic cell cycle" 0005871=kinesin complex "Cana, CG32955, CENP-ana, CENPana, Cenp_E, l(2)k07716, KIF 10, KIF10, CG33694, CP15516, DmCana, Cenp-E, CENP-E ana, CG4831" "IPR027640=Kinesin-like protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain" CG33694 16-Dec-15 2015_12 YDL058W(USO1) ENSXETG00000021319(CENPE) ENSMUSG00000045328(Cenpe) ENSG00000138778(CENPE) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0062669 EP3068 EP3068 http://flybase.net/reports/FBgn0062669.html gene EP(3)3068 16-Dec-15 2015_12 FBgn0024622 meso1 meso1 http://flybase.net/reports/FBgn0024622.html FBgn0024482 gene Clone1 16-Dec-15 2015_12 FBgn0029717 CG12684 http://flybase.net/reports/FBgn0029717.html protein_coding_gene IPR006629=LPS-induced tumour necrosis factor alpha factor CG12684 16-Dec-15 2015_12 viable FBgn0260604 2L2921 http://flybase.net/reports/FBgn0260604.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0013519 l(1)rp2 lethal (1) rp2 http://flybase.net/reports/FBgn0013519.html gene 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0264548 CR43927 http://flybase.net/reports/FBgn0264548.html non_protein_coding_gene CR43927 16-Dec-15 2015_12 FBgn0000754 fs(1)A427 female sterile (1) A427 http://flybase.net/reports/FBgn0000754.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0266937 CR45388 http://flybase.net/reports/FBgn0266937.html non_protein_coding_gene pri-mir-315 CR45388 16-Dec-15 2015_12 FBgn0015878 anon-48Ag anon-48Ag http://flybase.net/reports/FBgn0015878.html gene "transcript group IX, IX" 16-Dec-15 2015_12 FBgn0267789 CR46120 http://flybase.net/reports/FBgn0267789.html non_protein_coding_gene CR46120 16-Dec-15 2015_12 FBgn0016774 anon-70Dc anon-70Dc http://flybase.net/reports/FBgn0016774.html gene "gamma2, gamma2 transcript" 16-Dec-15 2015_12 FBgn0031373 CG15358 http://flybase.net/reports/FBgn0031373.html protein_coding_gene 0030246=carbohydrate binding mdcds_4396 "IPR016186=C-type lectin-like, IPR001304=C-type lectin, IPR016187=C-type lectin fold" CG15358 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000036655(Colec11),ENSMUSG00000038591(Colec10),ENSMUSG00000021795(Sftpd),ENSMUSG00000024863(Mbl2),ENSMUSG00000037780(Mbl1)" "ENSG00000118004(COLEC11),ENSG00000220191,ENSG00000165471(MBL2),ENSG00000184374(COLEC10),ENSG00000133661(SFTPD),ENSG00000182314,ENSG00000122854,ENSG00000122852(SFTPA1),ENSG00000185303(SFTPA2)" viable FBgn0069105 mus319 mutagen-sensitive 319 http://flybase.net/reports/FBgn0069105.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0043861 pf-5 pairing failure-5 http://flybase.net/reports/FBgn0043861.html gene 0007140=male meiosis "CG5, Complementation group 5" 16-Dec-15 2015_12 FBgn0033720 CG13160 http://flybase.net/reports/FBgn0033720.html protein_coding_gene IPR007484=Peptidase M28 CG13160 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0262854 CG43218 http://flybase.net/reports/FBgn0262854.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region MB8.chr3L.pasa.58 IPR002557=Chitin binding domain CG43218 16-Dec-15 2015_12 FBgn0002013 l(2)36Ff lethal (2) 36Ff http://flybase.net/reports/FBgn0002013.html gene l(2)E47 16-Dec-15 2015_12 lethal FBgn0035902 CG6683 http://flybase.net/reports/FBgn0035902.html protein_coding_gene IPR006578=MADF domain CG6683 16-Dec-15 2015_12 viable FBgn0031094 CG9578 http://flybase.net/reports/FBgn0031094.html protein_coding_gene 0005515=protein binding 0000077=DNA damage checkpoint 0005737=cytoplasm IPR007303=TIP41-like protein CG9578 16-Dec-15 2015_12 ENSDARG00000032353(zgc:66327) YPR040W(TIP41) WBGene00022803(ZK688.9) ENSXETG00000007092(Q5FW12_XENTR) ENSMUSG00000040843(Tiprl) ENSG00000143155(TIPRL) FBgn0261874 Z2-0115 http://flybase.net/reports/FBgn0261874.html gene 0030431=sleep 16-Dec-15 2015_12 behavior defective FBgn0026872 CG14777 http://flybase.net/reports/FBgn0026872.html FBgn0064788 protein_coding_gene 0016021=integral component of membrane "EG:80H7.10, BcDNA:RH63812" IPR007248=Mpv17/PMP22 CG14777 16-Dec-15 2015_12 YLR251W(SYM1) viable FBgn0004813 fs(2)ltoHM11 female sterile (2) ltoHM11 http://flybase.net/reports/FBgn0004813.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0001967 NimC3 Nimrod C3 http://flybase.net/reports/FBgn0001967.html FBgn0032542 protein_coding_gene 0006909=phagocytosis 0016021=integral component of membrane "l34Fa, br30, nimC3, l(2)34Fa, BG:DS05899.2, nimrod C3, CG16880, l(2)k00811, lethal (2) 34Fa, l(2)br30, NimC3, I(2)34Fa" IPR000742=EGF-like domain CG16880 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0021871 l(2)k13805 lethal (2) k13805 http://flybase.net/reports/FBgn0021871.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034002 CG8079 http://flybase.net/reports/FBgn0034002.html protein_coding_gene 0003676=nucleic acid binding "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome "IPR000467=G-patch domain, IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG8079 16-Dec-15 2015_12 ENSDARG00000060109(aggf1) WBGene00013224(Y55D9A.2) ENSMUSG00000021681(Aggf1) ENSG00000164252(AGGF1) viable FBgn0066369 chyo chyorny http://flybase.net/reports/FBgn0066369.html gene "0008355=olfactory learning, 0007611=learning or memory" Chyorny 16-Dec-15 2015_12 "learning defective,memory defective" FBgn0262609 CG43135 http://flybase.net/reports/FBgn0262609.html protein_coding_gene lincRNA.946 CG43135 16-Dec-15 2015_12 FBgn0259878 Fs Follistatin http://flybase.net/reports/FBgn0259878.html "FBgn0034004, FBgn0040746, FBgn0053466, FBgn0066117" protein_coding_gene "0032927=positive regulation of activin receptor signaling pathway, 0090099=negative regulation of decapentaplegic signaling pathway, 0032926=negative regulation of activin receptor signaling pathway" 0005576=extracellular region "dFS, dfs, dFol1, CG12956, Follistatin 1, CG33466, follistatin, CG12955, dFollistatin, fs, Fs, Fol1" "IPR002350=Kazal domain, IPR003645=Follistatin-like, N-terminal" CG33466 16-Dec-15 2015_12 "ENSDARG00000052846(fsta),ENSDARG00000057992(fstb),ENSDARG00000025670(zgc:114170)" ENSXETG00000023385(Q66JE7_XENTR) "ENSMUSG00000020325(Fstl3),ENSMUSG00000021765(Fst)" DRSC06259 E -0.431471755 1.276380601 2.969117166 1.169264284 0.336161645 -0.372515206 FBgn0033572 polyph polyphemus http://flybase.net/reports/FBgn0033572.html protein_coding_gene 0015171=amino acid transmembrane transporter activity "0042742=defense response to bacterium, 0006909=phagocytosis, 0003333=amino acid transmembrane transport, 0032504=multicellular organism reproduction" 0005615=extracellular space "polyph, polyphemus, CG12943" "IPR013057=Amino acid transporter, transmembrane domain" CG12943 16-Dec-15 2015_12 "YNL101W(AVT4),YKL146W(AVT3)" "immune response defective,short lived,conditional,viable" FBgn0053138 AGBE "1,4-Alpha-Glucan Branching Enzyme" http://flybase.net/reports/FBgn0053138.html FBgn0033801 protein_coding_gene "0004553=hydrolase activity, hydrolyzing O-glycosyl compounds, 0003844=1,4-alpha-glucan branching enzyme activity, 0043169=cation binding" "0008340=determination of adult lifespan, 0005978=glycogen biosynthetic process" "CG33138, CG4023, 1,4-alpha-glucan branching enzyme" "IPR006048=Alpha-amylase/branching enzyme, C-terminal all beta, IPR013783=Immunoglobulin-like fold, IPR006407=1,4-alpha-glucan-branching enzyme, GlgB, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR013781=Glycoside hydrolase, catalytic domain, IPR014756=Immunoglobulin E-set, IPR015902=Glycoside hydrolase, family 13, IPR004193=Glycoside hydrolase, family 13, N-terminal, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily" CG33138 16-Dec-15 2015_12 ENSDARG00000029051 YEL011W(GLC3) WBGene00011409(T04A8.7) ENSXETG00000004032(GBE1) ENSMUSG00000022707(Gbe1) ENSG00000114480(GBE1) "viable,fertile,long lived" DRSC06861 I 2.672299107 0.705485952 0.38423719 -0.311774029 -0.094217676 0.128247786 FBgn0039192 CG17784 http://flybase.net/reports/FBgn0039192.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG17784 16-Dec-15 2015_12 viable FBgn0259385 EP-1 http://flybase.net/reports/FBgn0259385.html gene 16-Dec-15 2015_12 visible wing vein FBgn0259430 EP-536 http://flybase.net/reports/FBgn0259430.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0262571 CG43111 http://flybase.net/reports/FBgn0262571.html protein_coding_gene CG43111 16-Dec-15 2015_12 FBgn0033490 CG12917 http://flybase.net/reports/FBgn0033490.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0016787=hydrolase activity" "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG12917 16-Dec-15 2015_12 viable FBgn0000980 fs(2)HO260 female sterile (2) HO260 http://flybase.net/reports/FBgn0000980.html gene fs(2)260A 16-Dec-15 2015_12 FBgn0260060 2L2953 http://flybase.net/reports/FBgn0260060.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0259251 EP-A http://flybase.net/reports/FBgn0259251.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0265539 CR44389 http://flybase.net/reports/FBgn0265539.html non_protein_coding_gene lincRNA.332 CR44389 16-Dec-15 2015_12 FBgn0264328 CR43787 http://flybase.net/reports/FBgn0264328.html non_protein_coding_gene CR43787 16-Dec-15 2015_12 FBgn0000342 coc collapsed ocelli http://flybase.net/reports/FBgn0000342.html gene 16-Dec-15 2015_12 "visible,recessive" "ocellus,ocellar bristle,abdomen,thorax,wing" FBgn0267893 CR46181 http://flybase.net/reports/FBgn0267893.html pseudogene_attribute ade5-related CR46181 16-Dec-15 2015_12 FBgn0046125 E(To)1 E(To)1 http://flybase.net/reports/FBgn0046125.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025929 hip7 hb-interacting protein 7 http://flybase.net/reports/FBgn0025929.html gene 16-Dec-15 2015_12 FBgn0050220 tRNA:CR30220 transfer RNA:CR30220 http://flybase.net/reports/FBgn0050220.html FBgn0060242 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "FBgn:0050220, CR30220, chr2R.trna38-GluCTC, tRNA:E:CTC:AE002787-b, AE002787.trna55-GluCTC" CR30220 16-Dec-15 2015_12 FBgn0051101 CG31101 http://flybase.net/reports/FBgn0051101.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039665 CG2310 http://flybase.net/reports/FBgn0039665.html protein_coding_gene CG2310 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0036697 rogdi rogdi http://flybase.net/reports/FBgn0036697.html protein_coding_gene "0007611=learning or memory, 0008355=olfactory learning, 0048149=behavioral response to ethanol" "CG7725, Rogdi" "IPR028241=RAVE subunit 2/Rogdi, IPR019386=Rogdi, leucine zipper-containing protein" CG7725 16-Dec-15 2015_12 ENSDARG00000037896(rogdi) WBGene00019196(H14A12.3) ENSXETG00000009143(ROGDI) ENSMUSG00000022540(Rogdi) ENSG00000067836(ROGDI) "memory defective,chemical sensitive,viable" FBgn0065883 l(2)SH0230 lethal (2) SH0230 http://flybase.net/reports/FBgn0065883.html gene l(2)SH2 0230 16-Dec-15 2015_12 "lethal,recessive" FBgn0051156 CG31156 http://flybase.net/reports/FBgn0051156.html "FBgn0038992, FBgn0038994" protein_coding_gene 0003676=nucleic acid binding 0006139=nucleobase-containing compound metabolic process "CG5257, CG5253" "IPR023323=Tex-like domain, IPR010994=RuvA domain 2-like, IPR023319=Tex-like protein, HTH domain, IPR006641=YqgF/RNase H-like domain, IPR003029=S1 domain, IPR023097=Tex RuvX-like domain, IPR022967=RNA-binding domain, S1, IPR012340=Nucleic acid-binding, OB-fold, IPR012337=Ribonuclease H-like domain, IPR018974=Tex-like protein, N-terminal" CG31156 16-Dec-15 2015_12 WBGene00022830(ZK973.1) ENSMUSG00000024135(Srbd1) ENSG00000068784(SRBD1) "viable,fertile" FBgn0264576 Pvr::Hsap\EGFR http://flybase.net/reports/FBgn0264576.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0060829 l(3)S050620 lethal (3) S050620 http://flybase.net/reports/FBgn0060829.html gene 0506/20 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0022258 l(2)k00909 lethal (2) k00909 http://flybase.net/reports/FBgn0022258.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034582 Cht9 Cht9 http://flybase.net/reports/FBgn0034582.html protein_coding_gene 0004568=chitinase activity "0006032=chitin catabolic process, 0005975=carbohydrate metabolic process" 0005615=extracellular space "CG10531, DmCHT9" "IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain, IPR001579=Glycoside hydrolase, chitinase active site, IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain" CG10531 16-Dec-15 2015_12 YDR371W(CTS2) "ENSMUSG00000062778(Chia),ENSMUSG00000043873(Bclp2),ENSMUSG00000040809(Chi3l3),ENSMUSG00000063779(Chi3l4),ENSMUSG00000027902(BC051070),ENSMUSG00000026450(Chit1),ENSMUSG00000074340(Ovgp1)" viable FBgn0041247 Gr28a Gustatory receptor 28a http://flybase.net/reports/FBgn0041247.html FBgn0031916 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gr28A1, GR28a, 28A.1, CG13787, GR28A.1, Gustatory receptor 28A2, Gustatory receptor 28A.1, Gr28A2" IPR013604=7TM chemoreceptor CG13787 16-Dec-15 2015_12 viable FBgn0030826 CG12995 http://flybase.net/reports/FBgn0030826.html protein_coding_gene CG12995 16-Dec-15 2015_12 viable FBgn0259407 EP-182 http://flybase.net/reports/FBgn0259407.html gene 16-Dec-15 2015_12 visible "wing,chaeta,ectopic" FBgn0262438 mir-1006 mir-1006 stem loop http://flybase.net/reports/FBgn0262438.html "FBgn0250802, FBgn0262292" miRNA_gene 0035278=negative regulation of translation involved in gene silencing by miRNA "miR-1006, CR42999, dme-mir-1006" CR42999 16-Dec-15 2015_12 "visible,lethal" "wing margin,wing vein" FBgn0082318 LpR2::sev LpR2::sev http://flybase.net/reports/FBgn0082318.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0037167 CG11425 http://flybase.net/reports/FBgn0037167.html protein_coding_gene 0008195=phosphatidate phosphatase activity "0006644=phospholipid metabolic process, 0016311=dephosphorylation" 0016020=membrane "WUN-like, LPP-like" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG11425 16-Dec-15 2015_12 viable FBgn0029140 P(3)97C P(3)97C http://flybase.net/reports/FBgn0029140.html gene 16-Dec-15 2015_12 FBgn0015940 fs(3)2755 fs(3)2755 http://flybase.net/reports/FBgn0015940.html gene fs(3)1755 16-Dec-15 2015_12 "female sterile,mitotic cell cycle defective" FBgn0033479 CG2292 http://flybase.net/reports/FBgn0033479.html protein_coding_gene 0016740=transferase activity 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane "IPR017850=Alkaline-phosphatase-like, core domain, IPR007070=GPI ethanolamine phosphate transferase 1, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017852=GPI ethanolamine phosphate transferase 1, C-terminal, IPR002591=Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase" CG2292 16-Dec-15 2015_12 YKL165C(MCD4) WBGene00021840(Y54E10BR.1) ENSMUSG00000056536(Pign) ENSG00000197563(PIGN) FBgn0060410 l(3)S130313a lethal (3) S130313a http://flybase.net/reports/FBgn0060410.html gene "1303/13, 1428/03" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0000261 Cat Catalase http://flybase.net/reports/FBgn0000261.html "FBgn0011460, FBgn0026841" protein_coding_gene "0020037=heme binding, 0016209=antioxidant activity, 0004096=catalase activity" "0055114=oxidation-reduction process, 0035206=regulation of hemocyte proliferation, 0038001=paracrine signaling, 0007568=aging, 0008340=determination of adult lifespan, 0072593=reactive oxygen species metabolic process, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0045471=response to ethanol, 0042542=response to hydrogen peroxide, 0003007=heart morphogenesis, 0006979=response to oxidative stress" "0005886=plasma membrane, 0005777=peroxisome" "catalase, DMCATHPO, cytosolic catalase, CAT, DROCATHPO, CATHPO, CatA, CATA, cat, U00145, bs36h11.y1, CT21282, CG6871" "IPR020835=Catalase-like domain, IPR018028=Catalase, mono-functional, haem-containing, IPR011614=Catalase core domain, IPR024708=Catalase active site, IPR010582=Catalase immune-responsive domain, IPR024711=Catalase, mono-functional, haem-containing, clades 1 and 3, IPR002226=Catalase haem-binding site" CG6871 16-Dec-15 2015_12 YDR256C(CTA1) "WBGene00000831(ctl-2),WBGene00000830(ctl-1),WBGene00013220(ctl-3)" "ENSXETG00000003981(BC090377.1),ENSXETG00000007561(TNeu041m16.1)" ENSMUSG00000027187(Cat) ENSG00000121691(CAT) adult stage " larval stage--pupal stage , larval stage--adult stage , embryonic stage | stage <7 , embryonic stage -- adult stage , adult stage , embryonic stage | stage >=7 , larval stage | third instar " " salivary gland

, ovary

, organism

, foregut && midgut && hindgut | restricted

, sense organ

, oenocyte

, embryonic oenocyte

, testis

, fat body

, dorsal mesothoracic disc

" "decreased cell number,conditional,oxidative stress response defective,lethal,viable,fertile,partially lethal - majority die,wild-type,chemical resistant,recessive,chemical sensitive,short lived,visible,locomotor rhythm defective" "lamellocyte,conditional,adult heart,RU486 conditional,intestinal stem cell,enteroendocrine cell,supernumerary,enterocyte,adult midgut,trichogen cell,progressive" FBgn0260323 GSd488 http://flybase.net/reports/FBgn0260323.html gene 16-Dec-15 2015_12 lethal FBgn0043030 l(2)42Da lethal (2) 42Da http://flybase.net/reports/FBgn0043030.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259237 CG42335 http://flybase.net/reports/FBgn0259237.html "FBgn0038900, FBgn0051177, FBgn0038899" protein_coding_gene "0008270=zinc ion binding, 0004177=aminopeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis "CG5845, CG13420, CG31177" "IPR024571=ERAP1-like C-terminal domain, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase" CG42335 16-Dec-15 2015_12 DRSC25666 K 0.792287047 0.037779505 -0.199822583 0.151143308 -0.49661553 1.584675305 FBgn0025881 snoRNA:Me18S-A1576 http://flybase.net/reports/FBgn0025881.html "FBgn0051877, FBgn0063390" snoRNA_gene 0005730=nucleolus "Me18S-A1576, snoRNA:Z5, U15snoRNA, Z5 snoRNA, Me18S-A1576(Z5), CR31877, snoRNA:U15" CR31877 16-Dec-15 2015_12 FBgn0259825 ifm(2)RS9 indirect flight muscle (2) RS9 http://flybase.net/reports/FBgn0259825.html gene 0007527=adult somatic muscle development 16-Dec-15 2015_12 viable indirect flight muscle FBgn0038617 CG12333 http://flybase.net/reports/FBgn0038617.html protein_coding_gene 0046331=lateral inhibition "IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG12333 16-Dec-15 2015_12 WBGene00015470(C05D2.10) ENSXETG00000018083(WDR37) ENSMUSG00000021147(Wdr37) ENSG00000047056(WDR37) "visible,partially lethal - majority die,some die during pupal stage" chaeta FBgn0085719 CG41603 http://flybase.net/reports/FBgn0085719.html FBan0041603 protein_coding_gene 16-Dec-15 2015_12 FBgn0043485 l(3)66EFa lethal (3) 66EFa http://flybase.net/reports/FBgn0043485.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028487 f-cup flyers-cup http://flybase.net/reports/FBgn0028487.html protein_coding_gene 0007265=Ras protein signal transduction "CG9611, BcDNA:GH09045, f-cup, gp150-like, flyers-cup" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG9611 16-Dec-15 2015_12 ENSDARG00000017708(lrrc40) ENSXETG00000012372(lrrc40) ENSMUSG00000063052(Lrrc40) ENSG00000066557(LRRC40) viable DRSC14139 E -1.134327234 0.237776169 -1.264695966 2.991555355 0.714991115 -0.192396682 FBgn0259593 B2031 http://flybase.net/reports/FBgn0259593.html gene 16-Dec-15 2015_12 visible wing FBgn0011987 tRNA:SeC transfer RNA:SeCys http://flybase.net/reports/FBgn0011987.html "FBgn0050024, FBgn0050256, FBgn0060051" tRNA_gene "0033415=UGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "Sec tRNA[[Ser]Sec], Selenocysteine tRNA, tRNA[[Ser]Sec], AE002787.trna26-SeC(e)TCA, tRNA:SeC:TCA:AE002787, Sec tRNA, SeCys-tRNA, chr2R:6873460..6873672, CR30024, chr2R.trna85-SeC(e)TCA, CR30256, tRNA[SeC], tRNA:SeCys" CR30024 16-Dec-15 2015_12 FBgn0014039 Su(tor)1-106 Su(tor)1-106 http://flybase.net/reports/FBgn0014039.html gene 16-Dec-15 2015_12 FBgn0267810 CR46135 http://flybase.net/reports/FBgn0267810.html non_protein_coding_gene CR46135 16-Dec-15 2015_12 FBgn0040637 CG11458 http://flybase.net/reports/FBgn0040637.html protein_coding_gene 0005615=extracellular space CG11458 16-Dec-15 2015_12 viable FBgn0024905 anon-H31 anon-H31 http://flybase.net/reports/FBgn0024905.html gene cDNA H31 16-Dec-15 2015_12 FBgn0036029 CG16719 http://flybase.net/reports/FBgn0036029.html protein_coding_gene 0007498=mesoderm development IPR010441=CH-like domain in sperm protein CG16719 16-Dec-15 2015_12 ENSDARG00000036189(spata4) "ENSMUSG00000027329(Spef1),ENSMUSG00000073795(6430531B16Rik)" ENSG00000101222(SPEF1) viable FBgn0085833 CR42206 http://flybase.net/reports/FBgn0085833.html FBan0042206 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0002676 mat(2)syn-D maternal effect syncytial blastoderm arrest D http://flybase.net/reports/FBgn0002676.html gene "0007349=cellularization, 0007279=pole cell formation" mat(2)synPA75 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0041225 Gr94a Gustatory receptor 94a http://flybase.net/reports/FBgn0041225.html FBgn0051280 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gr94E1, CG31280, GR94a, 94E.1, Gustatory receptor 94E.1, GR94E.1" IPR013604=7TM chemoreceptor CG31280 16-Dec-15 2015_12 "viable,fertile" DRSC13597 E 0.389268211 1.304535049 2.010941785 0.006495529 -0.377827672 -0.191876249 FBgn0065199 l(2)SH2312 lethal (2) SH2312 http://flybase.net/reports/FBgn0065199.html gene l(2)SH2 2312 16-Dec-15 2015_12 "lethal,recessive" FBgn0010790 l(3)02946 lethal (3) 02946 http://flybase.net/reports/FBgn0010790.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0038917 CG6678 http://flybase.net/reports/FBgn0038917.html protein_coding_gene "IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR000408=Regulator of chromosome condensation, RCC1" CG6678 16-Dec-15 2015_12 ENSDARG00000071074(wu:fc44f06) ENSMUSG00000038930(Rccd1) ENSG00000166965(RCCD1) viable FBgn0026175 SkpC SKP1-related C http://flybase.net/reports/FBgn0026175.html FBgn0031073 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "SkpC, Skp, CG11941, skpC, dskpC" "IPR016897=S-phase kinase-associated protein 1, IPR011333=POZ domain, IPR016072=SKP1 component, dimerisation, IPR001232=S-phase kinase-associated protein 1-like, IPR016073=SKP1 component, POZ domain" CG11941 16-Dec-15 2015_12 YDR328C(SKP1) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000176 Bg Bag http://flybase.net/reports/FBgn0000176.html gene "Uw, Uneven-wing" 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "wing,wing vein,wing vein L3,wing vein L4,wing vein L5,crossvein,wing basal cell 1,anterior crossvein" FBgn0067854 abz abruzzi http://flybase.net/reports/FBgn0067854.html gene "0045451=pole plasm oskar mRNA localization, 0045450=bicoid mRNA localization" 16-Dec-15 2015_12 lethal "egg chamber,germline clone,oocyte nucleus" FBgn0265550 CR44400 http://flybase.net/reports/FBgn0265550.html non_protein_coding_gene CR44400 16-Dec-15 2015_12 FBgn0036310 CG10969 http://flybase.net/reports/FBgn0036310.html protein_coding_gene CG10969 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267879 CR46167 http://flybase.net/reports/FBgn0267879.html pseudogene_attribute CG12717-related CR46167 16-Dec-15 2015_12 FBgn0010612 ATPsynG ATP synthase http://flybase.net/reports/FBgn0010612.html "FBgn0025552, FBgn0032325, FBgn0047026, FBgn0047151" protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0015992=proton transport, 0015986=ATP synthesis coupled proton transport" "0005811=lipid particle, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATP synthase G chain, anon-EST:Posey10, BcDNA:RE20862, ATP synthase g chain, lethal (2) 06225, CG6105, ATP synthase, subunit G, l(2)06225, BcDNA:RH28372, I(2)06225, F0/F1 ATP synthase G, ATPN" "IPR016702=Mitochondrial ATP synthase subunit g, animal, IPR006808=ATPase, F0 complex, subunit G, mitochondrial" CG6105 16-Dec-15 2015_12 ENSDARG00000011841(atp5l) "WBGene00000210(asg-2),WBGene00000209(asg-1)" ENSXETG00000010111() "ENSMUSG00000038717(Atp5l),ENSMUSG00000072460,ENSMUSG00000061863(Gm6822),ENSMUSG00000062918(Gm5426)" ENSG00000167283(ATP5L) "lethal,recessive" FBgn0085462 CG34433 http://flybase.net/reports/FBgn0085462.html "FBgn0039794, FBan0015541" protein_coding_gene CG15541 CG34433 16-Dec-15 2015_12 viable FBgn0014893 Wow Weakener of white http://flybase.net/reports/FBgn0014893.html gene 16-Dec-15 2015_12 "visible,recessive,sterile,lethal,suppressor of variegation" "testis,wing,pigment cell,Malpighian tubule" FBgn0259103 dar4 dendritic arbor reduction 4 http://flybase.net/reports/FBgn0259103.html gene 0050775=positive regulation of dendrite morphogenesis 16-Dec-15 2015_12 FBgn0065930 l(2)SH0136 lethal (2) SH0136 http://flybase.net/reports/FBgn0065930.html gene l(2)SH2 0136 16-Dec-15 2015_12 "lethal,recessive" FBgn0065296 l(2)SH1998 lethal (2) SH1998 http://flybase.net/reports/FBgn0065296.html gene l(2)SH2 1998 16-Dec-15 2015_12 "lethal,recessive" FBgn0024366 CG11409 http://flybase.net/reports/FBgn0024366.html protein_coding_gene EG:8D8.2 CG11409 16-Dec-15 2015_12 FBgn0004004 wd wavoid http://flybase.net/reports/FBgn0004004.html gene 16-Dec-15 2015_12 visible wing FBgn0003751 trk trunk http://flybase.net/reports/FBgn0003751.html protein_coding_gene 0005122=torso binding "0008358=maternal determination of anterior/posterior axis, embryo, 0007362=terminal region determination, 0008293=torso signaling pathway, 0008595=anterior/posterior axis specification, embryo" 0005576=extracellular region "Trunk, CG5619, fs(2)trunk" IPR029034=Cystine-knot cytokine CG5619 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage | 0-2 hr " " nurse cell

,

ubiquitous " "wild-type,developmental rate defective,lethal,maternal effect,female sterile,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,terminal phenotype,germline clone,non-rescuable maternal effect,viable" "abdominal segment 9,abdominal segment 10,telson,labrum,ocular segment,cephalic furrow,filzkorper,embryonic segment,abdomen,embryonic/first instar larval cuticle,maternal effect,embryonic labral segment,posterior endoderm,posterior midgut primordium,extended germ band embryo,abdominal segment 8,abdominal 8 ventral denticle belt,abdominal 9 ventral denticle belt,embryonic abdominal segment 8,embryo,germline clone,posterior,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7" FBgn0001633 l(1)dn13 lethal (1) discs normal 13 http://flybase.net/reports/FBgn0001633.html gene l(1)d.norm.-13 16-Dec-15 2015_12 lethal FBgn0086048 snoRNA:Me28S-U3344b http://flybase.net/reports/FBgn0086048.html snoRNA_gene "Me28S-Um3344b, mg28S-3344, CR34677" CR34677 16-Dec-15 2015_12 FBgn0062527 l(3)88EFe lethal (3) 88EFe http://flybase.net/reports/FBgn0062527.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0002085 l(2)49Fo lethal (2) 49Fo http://flybase.net/reports/FBgn0002085.html gene l(2)vr16 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0022990 p94 p94 http://flybase.net/reports/FBgn0022990.html gene 0008139=nuclear localization sequence binding 16-Dec-15 2015_12 FBgn0033717 CG8839 http://flybase.net/reports/FBgn0033717.html protein_coding_gene "0017064=fatty acid amide hydrolase activity, 0016884=carbon-nitrogen ligase activity, with glutamine as amido-N-donor" "0012505=endomembrane system, 0005811=lipid particle" "IPR023631=Amidase signature domain, IPR000120=Amidase" CG8839 16-Dec-15 2015_12 "ENSDARG00000008457(faah2a),ENSDARG00000054786(faah2b)" YDR242W(AMD2) WBGene00013164(Y53F4B.18) ENSXETG00000018191(FAAH2) ENSMUSG00000034171(Faah) ENSG00000165591(FAAH2) viable FBgn0051356 tRNA:CR31356 transfer RNA:CR31356 http://flybase.net/reports/FBgn0051356.html "FBgn0011989, FBgn0060038" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033439=ACA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:thr3:87BC, transfer RNA:thr3:87BC, tRNA:T:TGT:AE002708-a, tRNA[Thr][[3]], AE002708.trna4-ThrTGT, tRNA[[Thr]], tRNA:T3:87BC, chr3R.trna10-ThrTGT, CR31356" CR31356 16-Dec-15 2015_12 FBgn0022369 Pt-4 Larval protein-4 http://flybase.net/reports/FBgn0022369.html gene 16-Dec-15 2015_12 FBgn0058207 CG40207 http://flybase.net/reports/FBgn0058207.html FBan0040207 protein_coding_gene 16-Dec-15 2015_12 FBgn0065034 Antp::Dmag\Antp Antp http://flybase.net/reports/FBgn0065034.html engineered_fusion_gene 16-Dec-15 2015_12 visible "antenna,leg,ectopic,Keilin's organ,denticle belt,embryonic/first instar larval cuticle,ventral" FBgn0017437 anon-28Cb anon-28Cb http://flybase.net/reports/FBgn0017437.html gene unnamed 16-Dec-15 2015_12 FBgn0037115 CG11249 http://flybase.net/reports/FBgn0037115.html protein_coding_gene "0000287=magnesium ion binding, 0030955=potassium ion binding, 0004743=pyruvate kinase activity" 0006096=glycolytic process "IPR015795=Pyruvate kinase, C-terminal, IPR015794=Pyruvate kinase, alpha/beta, IPR001697=Pyruvate kinase, IPR015793=Pyruvate kinase, barrel, IPR011037=Pyruvate kinase-like, insert domain, IPR015806=Pyruvate kinase, beta-barrel insert domain" CG11249 16-Dec-15 2015_12 viable FBgn0000283 Cp190 Centrosomal protein 190kD http://flybase.net/reports/FBgn0000283.html FBgn0014463 protein_coding_gene "0003677=DNA binding, 0031208=POZ domain binding, 0008017=microtubule binding, 0003682=chromatin binding, 0046872=metal ion binding, 0005515=protein binding, 0043035=chromatin insulator sequence binding" "0007017=microtubule-based process, 0035191=nuclear axial expansion, 0090202=gene looping, 0031937=positive regulation of chromatin silencing, 0010468=regulation of gene expression" "0005813=centrosome, 0005634=nucleus, 0005704=polytene chromosome band, 0005875=microtubule associated complex, 0005700=polytene chromosome" "AbS1-4, Bx63, DMAP-190, Map190, Centrosomal protein 190, CP190, CP-190, Cen190, unnamed, E(mod)4-1, Centrosomal protein of 190 kDa, Centrosomal Protein 90, Bx-63, Centrosomal protein 190 kDa, Centrosomal Protein 190, Cen185, centrosomal protein 190, Centrosomal Protein of 190 kDa, Centrosomal Protein 190 kD, CG6384, Enhancer of mod(mdg4)4-1, DMAP190, Rb188, CEN190, DMAP 190, Dmap190, cp190, dmap190, CP190_DROME, CP-60" "IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR007087=Zinc finger, C2H2" CG6384 16-Dec-15 2015_12 "ENSDARG00000070658(si:ch211-222e23.7),ENSDARG00000056787(si:ch211-222e23.6),ENSDARG00000028949(si:ch211-236k19.4),ENSDARG00000005586(zgc:158317),ENSDARG00000069295(bcl6ab)" " adult stage | female , embryonic stage | 0-16 hr " embryonic stage | blastoderm "viable,lethal,partially,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,partially lethal - majority die,lethal - all die during embryonic stage,lethal - all die during third instar larval stage,heat sensitive" "cleavage nucleus,centrosome,microtubule,eye,tarsal segment,pretarsus,embryonic/larval salivary gland | third instar larval stage" FBgn0037995 CG3809 http://flybase.net/reports/FBgn0037995.html FBgn0044682 protein_coding_gene 0004001=adenosine kinase activity "0006166=purine ribonucleoside salvage, 0006167=AMP biosynthetic process" "DmAdk1, anon-WO0140519.193" "IPR011611=Carbohydrate kinase PfkB, IPR029056=Ribokinase-like, IPR001805=Adenosine kinase" CG3809 16-Dec-15 2015_12 YJR105W(ADO1) viable FBgn0013671 ms(3)neo94 ms(3)neo94 http://flybase.net/reports/FBgn0013671.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0026259 eIF5B eIF5B http://flybase.net/reports/FBgn0026259.html "FBgn0035446, FBgn0035447, FBgn0062068" protein_coding_gene "0003924=GTPase activity, 0005515=protein binding, 0003743=translation initiation factor activity, 0017151=DEAD/H-box RNA helicase binding, 0005525=GTP binding" 0006413=translational initiation "0005829=cytosol, 0005737=cytoplasm" "cIF2, Eif5b, anon-WO0118547.362, yIF2, CG10840, A1, IF2, eukaryotic initiation factor 5B, dIF2, cytoplasmic Initiation Factor 2, CG14970" "IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain, IPR023115=Translation initiation factor IF- 2, domain 3, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR004161=Translation elongation factor EFTu/EF1A, domain 2" CG10840 16-Dec-15 2015_12 ENSDARG00000016548 YAL035W(FUN12) WBGene00021857(iffb-1) ENSMUSG00000026083(Eif5b) ENSG00000158417(EIF5B) "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" DRSC08710 IE 1.005846276 2.475974956 3.925326219 -1.867289027 -1.156522938 1.33784455 FBgn0000502 dsr disrupted http://flybase.net/reports/FBgn0000502.html gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0062254 Su(Sd)4a-2 Suppressor of SD 4a-2 http://flybase.net/reports/FBgn0062254.html gene Su(SD)[4a-2] 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0029017 l(3)77CDh lethal (3) 77CDh http://flybase.net/reports/FBgn0029017.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039757 RpS7 Ribosomal protein S7 http://flybase.net/reports/FBgn0039757.html protein_coding_gene 0003735=structural constituent of ribosome "0006364=rRNA processing, 0006412=translation, 0042274=ribosomal small subunit biogenesis" "0030686=90S preribosome, 0032040=small-subunit processome, 0005634=nucleus, 0022627=cytosolic small ribosomal subunit" "ribosomal protein S7, CG1883" IPR000554=Ribosomal protein S7e CG1883 16-Dec-15 2015_12 ENSDARG00000042566(rps7) "YOR096W(RPS7A),YNL096C(RPS7B)" WBGene00004476(rps-7) ENSXETG00000001209(RPS7) "ENSMUSG00000061477(Rps7),ENSMUSG00000044424(Gm6472),ENSMUSG00000078106(Gm9493)" "ENSG00000171863(RPS7),ENSG00000183405" lethal DRSC15394 EK -0.491497248 0.842551401 4.152421541 -1.946055425 1.753770356 2.947685242 FBgn0260388 CG42514 http://flybase.net/reports/FBgn0260388.html "FBan0032158, FBgn0052158, FBgn0036635, FBgn0062056, FBgn0063802" protein_coding_gene 0004016=adenylate cyclase activity 0055085=transmembrane transport 0016021=integral component of membrane "CG4526, CG32158, AC" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG42514 16-Dec-15 2015_12 "viable,fertile" FBgn0027170 l(2)E105 lethal (2) E105 http://flybase.net/reports/FBgn0027170.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0020786 ri-s radius incompletus-similis http://flybase.net/reports/FBgn0020786.html gene 16-Dec-15 2015_12 FBgn0265834 CG44623 http://flybase.net/reports/FBgn0265834.html protein_coding_gene lincRNA.354 CG44623 16-Dec-15 2015_12 FBgn0265883 CR44672 http://flybase.net/reports/FBgn0265883.html non_protein_coding_gene lincRNA.609 CR44672 16-Dec-15 2015_12 FBgn0260254 GSd227 http://flybase.net/reports/FBgn0260254.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0039252 CG11771 http://flybase.net/reports/FBgn0039252.html FBgn0027773 protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis anon-EST:Posey100 "IPR001567=Peptidase M3A/M3B, IPR024079=Metallopeptidase, catalytic domain, IPR024077=Neurolysin/Thimet oligopeptidase, domain 2" CG11771 16-Dec-15 2015_12 WBGene00013997(ZK550.3) viable DRSC27732 K -0.092766066 -0.118831995 -0.233096141 0.985833028 -1.793622006 0.161078805 FBgn0066320 1360\T T http://flybase.net/reports/FBgn0066320.html transposable_element_gene 16-Dec-15 2015_12 FBgn0011067 l(1)Q20 lethal (1) Q20 http://flybase.net/reports/FBgn0011067.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0263048 CG43343 http://flybase.net/reports/FBgn0263048.html "FBgn0038954, FBgn0038955, FBgn0045280, FBgn0045289, FBgn0051169, FBan0031169" protein_coding_gene "0042803=protein homodimerization activity, 0051287=NAD binding, 0004367=glycerol-3-phosphate dehydrogenase [NAD+] activity" "0055114=oxidation-reduction process, 0005975=carbohydrate metabolic process, 0046168=glycerol-3-phosphate catabolic process, 0006072=glycerol-3-phosphate metabolic process" "0009331=glycerol-3-phosphate dehydrogenase complex, 0005829=cytosol" "gpdh-3, NEST:bs15d11, CG18427, NEST:bs16c09, CG31169" "IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011128=Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal, IPR006168=Glycerol-3-phosphate dehydrogenase, NAD-dependent, IPR016040=NAD(P)-binding domain, IPR017751=Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR006109=Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal" CG43343 16-Dec-15 2015_12 viable FBgn0024600 roam roaming http://flybase.net/reports/FBgn0024600.html gene 0007411=axon guidance 16-Dec-15 2015_12 viable "presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,Bolwig nerve,Bolwig organ" FBgn0028940 Cyp28a5 Cyp28a5 http://flybase.net/reports/FBgn0028940.html "FBgn0032540, FBgn0043826" protein_coding_gene "0004497=monooxygenase activity, 0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "BEST:GH10483, gh10483, DS00180.11, CG8864, cytochrome P450, Cyp28A5, BG:DS00180.11, cyp28a5, 28a5" "IPR017972=Cytochrome P450, conserved site, IPR002403=Cytochrome P450, E-class, group IV, IPR001128=Cytochrome P450" CG8864 16-Dec-15 2015_12 YHR007C(ERG11) FBgn0002496 l(3)SG57 lethal (3) SG57 http://flybase.net/reports/FBgn0002496.html gene l(3)7m147 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0035181 CG9205 http://flybase.net/reports/FBgn0035181.html protein_coding_gene "IPR000648=Oxysterol-binding protein, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG9205 16-Dec-15 2015_12 viable FBgn0013301 ProtB Protamine B http://flybase.net/reports/FBgn0013301.html "FBgn0010308, FBgn0063256" protein_coding_gene 0003677=DNA binding "0007286=spermatid development, 0035092=sperm chromatin condensation, 0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin "protamine B, mst35b, Protamine, prot-B, Protamine B, dProtamineB, ProtB, protB, BcDNA:GH11850, protamine (mst35Bb), CG4478, dProtB, protamine, Mst35Bb, ProtamineB, BG:DS03431.3, Male-specific-transcript-35Bb" "IPR009071=High mobility group box domain, IPR024460=Protein of unknown function DUF1074" CG4478 16-Dec-15 2015_12 "male fertile,viable" FBgn0030596 CG12398 http://flybase.net/reports/FBgn0030596.html protein_coding_gene "0004344=glucose dehydrogenase activity, 0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity" "0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process" 0042600=chorion Dm GMCgamma1 "IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG12398 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) viable FBgn0039235 CG10899 http://flybase.net/reports/FBgn0039235.html FBgn0063362 protein_coding_gene "0008270=zinc ion binding, 0004089=carbonate dehydratase activity" 0006730=one-carbon metabolic process BcDNA:AT02719 "IPR018338=Carbonic anhydrase, alpha-class, conserved site, IPR023561=Carbonic anhydrase, alpha-class, IPR001148=Alpha carbonic anhydrase" CG10899 16-Dec-15 2015_12 WBGene00000283(cah-5) viable FBgn0029588 CG14798 http://flybase.net/reports/FBgn0029588.html FBgn0047084 protein_coding_gene BcDNA:RE57135 CG14798 16-Dec-15 2015_12 FBgn0036655 CG13031 http://flybase.net/reports/FBgn0036655.html protein_coding_gene CG13031 16-Dec-15 2015_12 "viable,fertile" FBgn0037370 CG1236 http://flybase.net/reports/FBgn0037370.html protein_coding_gene "0004617=phosphoglycerate dehydrogenase activity, 0051287=NAD binding" 0055114=oxidation-reduction process "IPR029753=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site, IPR016040=NAD(P)-binding domain, IPR006140=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR006139=D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain" CG1236 16-Dec-15 2015_12 "ENSDARG00000019986(zgc:77636),ENSDARG00000068264(grhpr)" YNL274C(GOR1) "ENSXETG00000006541(BC091063.1),ENSXETG00000025842(),ENSXETG00000006536(grhpr)" ENSMUSG00000035637(Grhpr) ENSG00000137106(GRHPR) "viable,fertile" FBgn0022362 Pt-9A Adult protein-9A http://flybase.net/reports/FBgn0022362.html gene 16-Dec-15 2015_12 FBgn0035985 Cpr67B Cuticular protein 67B http://flybase.net/reports/FBgn0035985.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG3672 IPR000618=Insect cuticle protein CG3672 16-Dec-15 2015_12 "viable,fertile" FBgn0040331 EY2-6 EY2-6 http://flybase.net/reports/FBgn0040331.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043356 EP2599 EP2599 http://flybase.net/reports/FBgn0043356.html gene 16-Dec-15 2015_12 visible "trichogen cell,tormogen cell" FBgn0069236 gl(1)83-27 gl(1)83-27 http://flybase.net/reports/FBgn0069236.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic abdominal segment" FBgn0005357 su(tu-bw) suppressor of tumor-brown http://flybase.net/reports/FBgn0005357.html gene suppressor of tumor with brown 16-Dec-15 2015_12 FBgn0259322 C623 http://flybase.net/reports/FBgn0259322.html gene 16-Dec-15 2015_12 visible "wing hair,wing margin,wing vein" FBgn0085201 CG34172 http://flybase.net/reports/FBgn0085201.html protein_coding_gene 0004129=cytochrome-c oxidase activity 0005746=mitochondrial respiratory chain "IPR003177=Cytochrome c oxidase, subunit VIIa" CG34172 16-Dec-15 2015_12 FBgn0051394 CG31394 http://flybase.net/reports/FBgn0051394.html FBgn0064880 protein_coding_gene BcDNA:RE47391 16-Dec-15 2015_12 FBgn0002492 l(3)SG52 lethal (3) SG52 http://flybase.net/reports/FBgn0002492.html gene l(3)15m-25 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0053155 CG33155 http://flybase.net/reports/FBgn0053155.html "FBgn0047273, FBgn0064127, FBtr0089466, FBpp0088473, FBtr0089467, FBpp0088474, FBtr0089468, FBpp0088475, FBtr0089469, FBpp0088476" protein_coding_gene 0035167=larval lymph gland hemopoiesis "BcDNA:GM05817, CG33184, CR33155" CG33155 16-Dec-15 2015_12 FBgn0085487 CG34458 http://flybase.net/reports/FBgn0085487.html "FBgn0034147, FBan0005197" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP118, CG5197" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR010916=TonB box, conserved site" CG34458 16-Dec-15 2015_12 "ENSDARG00000029841,ENSDARG00000060313(LOC100334482),ENSDARG00000071525" FBgn0034906 CG13561 http://flybase.net/reports/FBgn0034906.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG13561 16-Dec-15 2015_12 FBgn0037030 CG3288 http://flybase.net/reports/FBgn0037030.html protein_coding_gene CG3288 16-Dec-15 2015_12 FBgn0016989 ms(3)25 ms(3)25 http://flybase.net/reports/FBgn0016989.html gene 16-Dec-15 2015_12 FBgn0003901 twl twirl http://flybase.net/reports/FBgn0003901.html gene 16-Dec-15 2015_12 "viable,visible" wing FBgn0029085 flc fleece http://flybase.net/reports/FBgn0029085.html gene 16-Dec-15 2015_12 "viable,visible,recessive" macrochaeta FBgn0062693 EP1246 EP1246 http://flybase.net/reports/FBgn0062693.html gene EP(3)1246 16-Dec-15 2015_12 FBgn0025796 Su(var)501 Suppressor of variegation 501 http://flybase.net/reports/FBgn0025796.html gene Su-var(2)501 16-Dec-15 2015_12 FBgn0082951 snoRNA:Me18S-C1366 snoRNA:Me18S-C1366 http://flybase.net/reports/FBgn0082951.html snoRNA_gene "CR34532, Me18S-C1366, Me18S-Cm1366, chr2R:10136644..10136796" CR34532 16-Dec-15 2015_12 FBgn0065147 l(3)SH081 lethal (3) SH081 http://flybase.net/reports/FBgn0065147.html gene l(2)SH3 081 16-Dec-15 2015_12 "lethal,recessive" FBgn0002028 l(2)37Bj lethal (2) 37Bj http://flybase.net/reports/FBgn0002028.html gene "Bj, l(2)E35" 16-Dec-15 2015_12 lethal FBgn0044505 BS\gag gag http://flybase.net/reports/FBgn0044505.html transposable_element_gene 16-Dec-15 2015_12 FBgn0001239 Hooked-veins Hooked veins http://flybase.net/reports/FBgn0001239.html gene "Hv, Hooked-veins" 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" "wing vein,crossvein,eye" FBgn0052266 CG32266 http://flybase.net/reports/FBgn0052266.html FBgn0063187 protein_coding_gene BcDNA:GM24338 CG32266 16-Dec-15 2015_12 viable FBgn0260288 GSd492 http://flybase.net/reports/FBgn0260288.html gene 16-Dec-15 2015_12 lethal FBgn0003292 rt rotated abdomen http://flybase.net/reports/FBgn0003292.html protein_coding_gene 0004169=dolichyl-phosphate-mannose-protein mannosyltransferase activity "0016203=muscle attachment, 0007525=somatic muscle development, 0045214=sarcomere organization, 0035269=protein O-linked mannosylation, 0007385=specification of segmental identity, abdomen, 0060025=regulation of synaptic activity" "0005783=endoplasmic reticulum, 0016020=membrane, 0016021=integral component of membrane" "fs(3)neo1, roa, pomt, Rotated abdomen, Rot_abd, CG6097, POMT1, dPomt1, Drosophila Protein O-mannosyltransferase 1, Rotated Abdomen, DPOMT1, Rt, dPOMT1" "IPR003342=Glycosyl transferase family 39/83, IPR027005=Glycosyltransferase 39-like, IPR016093=MIR motif" CG6097 16-Dec-15 2015_12 ENSDARG00000067670(pomt1) ENSXETG00000001481(pomt1) ENSMUSG00000039254(Pomt1) ENSG00000130714(POMT1) "female sterile,recessive,visible,male fertile,reduced,female fertile,neurophysiology defective,locomotor behavior defective,flight defective,viable,male sterile,lethal,heat sensitive,short lived" "adult abdomen,adult cuticle,embryonic/larval muscle system,muscle attachment site,sarcomere | third instar larval stage,embryonic/larval somatic muscle,lateral,abdomen" DRSC11391 K -0.05871842 0.207356181 -0.337365076 0.175107412 -1.222954938 -1.944121112 FBgn0031987 CG12375 http://flybase.net/reports/FBgn0031987.html protein_coding_gene IPR001279=Metallo-beta-lactamase CG12375 16-Dec-15 2015_12 WBGene00013176(Y53F4B.39) ENSXETG00000015953(LACTB2) ENSMUSG00000025937(Lactb2) ENSG00000147592(LACTB2) viable FBgn0039945 CG17159 http://flybase.net/reports/FBgn0039945.html "FBgn0022354, FBgn0058460, FBan0017159" protein_coding_gene "anon-20Ea, unnamed, CG40460, FBgn0058460" CG17159 16-Dec-15 2015_12 FBgn0260644 CG42536 http://flybase.net/reports/FBgn0260644.html protein_coding_gene CG42536 16-Dec-15 2015_12 FBgn0061131 l(3)S002401b lethal (3) S002401b http://flybase.net/reports/FBgn0061131.html gene 0024/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0037670 Ibf1 Insulator binding factor 1 http://flybase.net/reports/FBgn0037670.html protein_coding_gene "0043565=sequence-specific DNA binding, 0005515=protein binding, 0043035=chromatin insulator sequence binding, 0046982=protein heterodimerization activity" 0031937=positive regulation of chromatin silencing 0005634=nucleus CG8436 CG8436 16-Dec-15 2015_12 viable DRSC16419 E 1.183642657 0.799364511 1.059615955 1.508087089 -1.437248096 -0.765726161 FBgn0040719 CG15357 http://flybase.net/reports/FBgn0040719.html protein_coding_gene CG15357 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0053477 CG33477 http://flybase.net/reports/FBgn0053477.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33477 16-Dec-15 2015_12 FBgn0037416 Osi9 Osiris 9 http://flybase.net/reports/FBgn0037416.html protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis 0005887=integral component of plasma membrane "Osiris, CG15592" IPR012464=Protein of unknown function DUF1676 CG15592 16-Dec-15 2015_12 viable FBgn0040112 l(3)S049314a lethal (3) S049314a http://flybase.net/reports/FBgn0040112.html gene "0493/14, l(3)S049314, 493/14" 16-Dec-15 2015_12 "lethal,recessive" FBgn0010080 Rst(3)mth1 Resistance (3) malathion 1 http://flybase.net/reports/FBgn0010080.html gene 16-Dec-15 2015_12 FBgn0033056 CG7856 http://flybase.net/reports/FBgn0033056.html protein_coding_gene CG7856 16-Dec-15 2015_12 viable FBgn0031157 CG1503 http://flybase.net/reports/FBgn0031157.html protein_coding_gene 0008234=cysteine-type peptidase activity 0006508=proteolysis "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG1503 16-Dec-15 2015_12 WBGene00006738(ulp-3) "ENSXETG00000005208(),ENSXETG00000014299()" viable FBgn0262796 Pgant35A::Hsap\GALNT11 http://flybase.net/reports/FBgn0262796.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0022099 l(2)k07136 lethal (2) k07136 http://flybase.net/reports/FBgn0022099.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0012003 tRNA:V3b:92Ba transfer RNA:val3b:92Ba http://flybase.net/reports/FBgn0012003.html "FBgn0003855, FBgn0011997, FBgn0051214, FBgn0060020" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033452=GUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002708.trna41-ValCAC, CR31214, tRNA:val3b:92Ba, tRNA:V3b, tRNA[Val][[3b]], valine tRNA, tRNA:V:CAC:AE002708-c, chr3R.trna47-ValCAC" CR31214 16-Dec-15 2015_12 FBgn0015728 Etr1 ETR-1-like http://flybase.net/reports/FBgn0015728.html gene etr-1 16-Dec-15 2015_12 FBgn0015475 l(2)45Ac lethal (2) 45Ac http://flybase.net/reports/FBgn0015475.html gene 16-Dec-15 2015_12 lethal FBgn0028066 l(3)S091014 lethal (3) S091014 http://flybase.net/reports/FBgn0028066.html gene 0910/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0037238 CG1090 http://flybase.net/reports/FBgn0037238.html FBan0001090 protein_coding_gene "0008273=calcium, potassium:sodium antiporter activity" "0006814=sodium ion transport, 0006816=calcium ion transport, 0055085=transmembrane transport" 0016021=integral component of membrane "IPR004481=Sodium/potassium/calcium exchanger, IPR004837=Sodium/calcium exchanger membrane region" CG1090 16-Dec-15 2015_12 YDL206W() "ENSXETG00000000793(SLC24A3),ENSXETG00000010290(SLC24A4)" viable FBgn0005473 l(1)ts967 lethal (1) ts967 http://flybase.net/reports/FBgn0005473.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0267712 CR46045 http://flybase.net/reports/FBgn0267712.html non_protein_coding_gene CR46045 16-Dec-15 2015_12 FBgn0010184 tu(2)e144 tu(2)e144 http://flybase.net/reports/FBgn0010184.html gene e144 16-Dec-15 2015_12 FBgn0039120 Nup98-96 Nucleoporin 98-96kD http://flybase.net/reports/FBgn0039120.html "FBgn0021781, FBgn0039119" protein_coding_gene "0005487=nucleocytoplasmic transporter activity, 0005515=protein binding" "0006909=phagocytosis, 0010628=positive regulation of gene expression, 0007184=SMAD protein import into nucleus, 0030718=germ-line stem cell maintenance, 0035167=larval lymph gland hemopoiesis" "0005643=nuclear pore, 0044613=nuclear pore central transport channel" "nup145, Nup 98, NUP98, l(3)95BCd, CG10201, Nup98, Nucleoporin 98-96, Nup98/96, Nup 96, Nup-98, nucleoporin98-96, Nucleoporin 98, CG10198, nup98-96, Nup96, Nup, Nup96-98, Nup98-Nup96" "IPR025574=Nucleoporin FG repeat, IPR007230=Peptidase S59, nucleoporin, IPR021967=Nuclear protein 96" CG10198 16-Dec-15 2015_12 ENSDARG00000001766 YGL092W(NUP145) WBGene00003796(npp-10) ENSMUSG00000063550(Nup98) ENSG00000110713(NUP98) "lethal,recessive,cell growth defective" "male germline cell,male germline stem cell,primary gonial cell,spermatogonium,male fusome,female fusome,nurse cell spectrosome,female germline cell" DRSC14209 EK 1.242735482 0.299723518 -1.603496707 -2.777895182 0.480003666 1.567589113 FBgn0002458 l(3)SG11 lethal (3) SG11 http://flybase.net/reports/FBgn0002458.html gene l(3)15m-33 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0265190 PIG-S "Phosphatidylinositol glycan anchor biosynthesis, class S ortholog (H. sapiens)" http://flybase.net/reports/FBgn0265190.html "FBgn0051120, FBgn0039247, FBgn0039248" protein_coding_gene 0003923=GPI-anchor transamidase activity "0042996=regulation of Golgi to plasma membrane protein transport, 0016255=attachment of GPI anchor to protein, 0045313=rhabdomere membrane biogenesis" "0005654=nucleoplasm, 0042765=GPI-anchor transamidase complex, 0012505=endomembrane system" "CG31120, CG6031, CG44255, CG13644, sud2" IPR019540=Phosphatidylinositol-glycan biosynthesis class S protein CG44255 16-Dec-15 2015_12 lethal - all die before end of embryonic stage "rhabdomere,somatic clone" FBgn0051191 CG31191 http://flybase.net/reports/FBgn0051191.html "FBgn0038841, FBgn0038843" protein_coding_gene "CG17277, CG17276" CG31191 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0020467 Dsor3 Downstream of raf 3 http://flybase.net/reports/FBgn0020467.html gene 16-Dec-15 2015_12 FBgn0265356 tn thin http://flybase.net/reports/FBgn0265356.html "FBgn0034412, FBgn0003726" protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0046716=muscle cell cellular homeostasis, 0048747=muscle fiber development, 0006941=striated muscle contraction, 0016567=protein ubiquitination, 0030239=myofibril assembly" 0030018=Z disc "CG15105, l(2)tn, Another B-box Affiliate, another B-box affiliate, abba, Abba, Another B-Box Affiliate, l(2)thin" "IPR018957=Zinc finger, C3HC4 RING-type, IPR001258=NHL repeat, IPR001841=Zinc finger, RING-type, IPR013017=NHL repeat, subgroup, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011042=Six-bladed beta-propeller, TolB-like" CG15105 16-Dec-15 2015_12 "ENSDARG00000031817(zgc:113099),ENSDARG00000005397(trim3b),ENSDARG00000063711(trim3a)" WBGene00003597(nhl-1) "ENSMUSG00000036989(Trim3),ENSMUSG00000027993(Trim2)" "ENSG00000110171(TRIM3),ENSG00000109654(TRIM2)" FBgn0283439 CG46281 http://flybase.net/reports/FBgn0283439.html FBgn0038111 protein_coding_gene CG12360 CG46281 16-Dec-15 2015_12 FBgn0060466 l(3)S113403 lethal (3) S113403 http://flybase.net/reports/FBgn0060466.html gene 1134/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0014360 ms(3)neo6 ms(3)neo6 http://flybase.net/reports/FBgn0014360.html gene 16-Dec-15 2015_12 male sterile FBgn0036905 ms(3)76Ca male sterile (3) 76Ca http://flybase.net/reports/FBgn0036905.html FBgn0044597 protein_coding_gene 0048515=spermatid differentiation "CG14101, anon-WO0140519.34" CG14101 16-Dec-15 2015_12 "WBGene00007503(C09H10.9),WBGene00013175(Y53F4B.36)" "male sterile,viable,fertile" FBgn0004950 1688-3C 1.688 satellite-related 3C http://flybase.net/reports/FBgn0004950.html repeat_region 1.688 16-Dec-15 2015_12 FBgn0038394 CG10264 http://flybase.net/reports/FBgn0038394.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG10264 16-Dec-15 2015_12 viable FBgn0002418 l(3)DTS6 lethal (3) DTS6 http://flybase.net/reports/FBgn0002418.html gene DTS-6 16-Dec-15 2015_12 "female sterile,lethal - all die before end of pupal stage,dominant,heat sensitive,some die during pupal stage" FBgn0263740 eIF-2ë_ Eukaryotic initiation factor 2ë_ http://flybase.net/reports/FBgn0263740.html FBgn0003600 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "eIF-2G, eIF2G, CG6476, gamma subunit of the translation initiation factor eIF2, eIF2gamma, 51kDa protein, CG43665" "IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR015256=Translation initiation factor 2, gamma subunit, C-terminal, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain" CG43665 16-Dec-15 2015_12 FBgn0023125 anon-10Ai anon-10Ai http://flybase.net/reports/FBgn0023125.html gene 1 16-Dec-15 2015_12 FBgn0265657 CR44464 http://flybase.net/reports/FBgn0265657.html non_protein_coding_gene lincRNA.324 CR44464 16-Dec-15 2015_12 FBgn0065643 l(2)SH0755 lethal (2) SH0755 http://flybase.net/reports/FBgn0065643.html gene l(2)SH2 0755 16-Dec-15 2015_12 "lethal,recessive" FBgn0265626 CG44434 http://flybase.net/reports/FBgn0265626.html FBgn0034374 protein_coding_gene CG15086 CG44434 16-Dec-15 2015_12 viable FBgn0032140 CG13117 http://flybase.net/reports/FBgn0032140.html FBgn0062840 protein_coding_gene BcDNA:SD27505 CG13117 16-Dec-15 2015_12 viable FBgn0028911 tRNA:P:35Bb tRNA:P:35Bb http://flybase.net/reports/FBgn0028911.html "FBgn0051979, FBgn0060120" tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "BG:DS01486.3, AE002690.trna14-ProAGG, CR31979, tRNA:P:AGG:AE002690-d, tRNA:pro, chr2L.trna23-ProAGG" CR31979 16-Dec-15 2015_12 FBgn0051661 CG31661 http://flybase.net/reports/FBgn0051661.html FBgn0031342 protein_coding_gene 0004190=aspartic-type endopeptidase activity "0007306=eggshell chorion assembly, 0006508=proteolysis" 0042600=chorion "CG10872, aspartic-type endopeptidase" "IPR021109=Aspartic peptidase domain, IPR001461=Aspartic peptidase" CG31661 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0267654 CR45992 http://flybase.net/reports/FBgn0267654.html non_protein_coding_gene CR45992 16-Dec-15 2015_12 FBgn0029707 CG12688 http://flybase.net/reports/FBgn0029707.html protein_coding_gene CG12688 16-Dec-15 2015_12 viable FBgn0033933 CG10104 http://flybase.net/reports/FBgn0033933.html protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis "IPR021109=Aspartic peptidase domain, IPR012848=Aspartic peptidase, N-terminal, IPR001461=Aspartic peptidase, IPR001969=Aspartic peptidase, active site" CG10104 16-Dec-15 2015_12 YPL154C(PEP4) WBGene00000217(asp-4) ENSMUSG00000007891(Ctsd) ENSG00000117984(CTSD) viable FBgn0265766 CR44573 http://flybase.net/reports/FBgn0265766.html non_protein_coding_gene CR44573 16-Dec-15 2015_12 FBgn0035959 CG4911 http://flybase.net/reports/FBgn0035959.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO4 IPR001810=F-box domain CG4911 16-Dec-15 2015_12 "ENSDARG00000021882,ENSDARG00000000722(fbxl3a),ENSDARG00000037738(LOC564855)" ENSXETG00000011443(FBXO33) ENSMUSG00000035329 ENSG00000165355(FBXO33) viable FBgn0062529 l(3)88EFc lethal (3) 88EFc http://flybase.net/reports/FBgn0062529.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0060766 l(3)S062516b lethal (3) S062516b http://flybase.net/reports/FBgn0060766.html gene 0625/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0000743 fs(1)A214 female sterile (1) A214 http://flybase.net/reports/FBgn0000743.html gene fs(1)214 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" blastoderm embryo FBgn0065200 l(2)SH2307 lethal (2) SH2307 http://flybase.net/reports/FBgn0065200.html gene l(2)SH2 2307 16-Dec-15 2015_12 "lethal,recessive" FBgn0262239 mir-961 mir-961 stem loop http://flybase.net/reports/FBgn0262239.html miRNA_gene "0060259=regulation of feeding behavior, 0006955=immune response" "CR42946, dme-mir-961, miR-961, 961" CR42946 16-Dec-15 2015_12 viable FBgn0030237 CG15209 http://flybase.net/reports/FBgn0030237.html "FBgn0027706, FBgn0062858" protein_coding_gene "BcDNA:SD22308, anon-EST:Posey262" CG15209 16-Dec-15 2015_12 viable FBgn0085505 CR40629 http://flybase.net/reports/FBgn0085505.html FBan0040629 non_protein_coding_gene CG40629 CR40629 16-Dec-15 2015_12 FBgn0069322 X-162-11 X-162-11 http://flybase.net/reports/FBgn0069322.html gene 0035290=trunk segmentation 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0033341 MrgBP MRG/MORF4L binding protein http://flybase.net/reports/FBgn0033341.html protein_coding_gene "0043486=histone exchange, 0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis, 0016573=histone acetylation" 0035267=NuA4 histone acetyltransferase complex "CG13746, MrgBP, MRGBP, dMrgBP, dMrgB" IPR012423=Chromatin modification-related protein Eaf7/MRGBP CG13746 16-Dec-15 2015_12 ENSDARG00000028894(c20orf20) YNL136W(EAF7) ENSXETG00000006112(Q561N9_XENTR) ENSMUSG00000027569(1600027N09Rik) ENSG00000101189(C20orf20) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC06417 I -1.711745945 -1.781235958 0.090520897 -1.492752747 -1.403166036 -0.664222511 FBgn0029913 Cht11 Cht11 http://flybase.net/reports/FBgn0029913.html protein_coding_gene 0004568=chitinase activity "0005975=carbohydrate metabolic process, 0006032=chitin catabolic process" CG3044 "IPR017853=Glycoside hydrolase superfamily, IPR001579=Glycoside hydrolase, chitinase active site, IPR029070=Chitinase insertion domain, IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain" CG3044 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable,fertile,immune response defective" FBgn0265453 CR44353 http://flybase.net/reports/FBgn0265453.html non_protein_coding_gene CR44353 16-Dec-15 2015_12 FBgn0084127 LA00287 LA00287 http://flybase.net/reports/FBgn0084127.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013936 E(nd)195 Enhancer(notchoid)195 http://flybase.net/reports/FBgn0013936.html gene 16-Dec-15 2015_12 FBgn0262002 CG42820 http://flybase.net/reports/FBgn0262002.html "FBgn0032037, FBan0013394" protein_coding_gene CG13394 CG42820 16-Dec-15 2015_12 "fertile,viable" FBgn0014006 Ask1 Apoptotic signal-regulating kinase 1 http://flybase.net/reports/FBgn0014006.html protein_coding_gene "0004709=MAP kinase kinase kinase activity, 0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity" "0006468=protein phosphorylation, 0012501=programmed cell death, 0000186=activation of MAPKK activity, 0032874=positive regulation of stress-activated MAPK cascade, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0046330=positive regulation of JNK cascade, 0008360=regulation of cell shape, 0000165=MAPK cascade" 1902911=protein kinase complex "dASK, MEKK5/ASK1, DASK, pk92B, D-ASK, Ask1, Apoptotic signal-regulating kinase 1, Protein kinase at 92B, DASK1, CG4720, ASK1, dAsk1, Pk92B, DPk92B/ASK1" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR025136=Domain of unknown function DUF4071, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011990=Tetratricopeptide-like helical domain, IPR017441=Protein kinase, ATP binding site" CG4720 16-Dec-15 2015_12 "ENSDARG00000013310,ENSDARG00000005416(map3k5),ENSDARG00000069933(wu:fa92h04)" WBGene00003822(nsy-1) "ENSXETG00000006210(MAP3K15),ENSXETG00000002476(MAP3K5)" "ENSMUSG00000031303,ENSMUSG00000071369(Map3k5)" "ENSG00000180815(MAP3K15),ENSG00000197442(MAP3K5)" "body color defective,heat sensitive,viable" "adult thorax,adult cuticle,wing,heat sensitive" DRSC16789 K -1.000865233 0.673898258 0.229869483 0.393084571 -1.575391561 -0.568029705 FBgn0010855 l(3)05088 lethal (3) 05088 http://flybase.net/reports/FBgn0010855.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266305 CR44970 http://flybase.net/reports/FBgn0266305.html non_protein_coding_gene CR44970 16-Dec-15 2015_12 FBgn0265664 CR44471 http://flybase.net/reports/FBgn0265664.html non_protein_coding_gene lincRNA.950 CR44471 16-Dec-15 2015_12 FBgn0082690 E(ftz)1027 E(ftz)1027 http://flybase.net/reports/FBgn0082690.html gene 1027 16-Dec-15 2015_12 FBgn0027328 l(1)G0024 lethal (1) G0024 http://flybase.net/reports/FBgn0027328.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0044865 MMS-2 MMS-2 http://flybase.net/reports/FBgn0044865.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0010346 Mst75Cb Male-specific RNA 75Cb http://flybase.net/reports/FBgn0010346.html FBgn0002861 gene "mst-2, mst(3)ag-2, Mst75C, mst(3)ag-15B" 16-Dec-15 2015_12 FBgn0020838 l(2)F42 Florida 42 http://flybase.net/reports/FBgn0020838.html gene l(2)Fla.'42 16-Dec-15 2015_12 lethal FBgn0281846 ato::da http://flybase.net/reports/FBgn0281846.html engineered_fusion_gene Ato-Da 16-Dec-15 2015_12 FBgn0266456 CG45081 http://flybase.net/reports/FBgn0266456.html protein_coding_gene CG45081 16-Dec-15 2015_12 FBgn0036249 CG11560 http://flybase.net/reports/FBgn0036249.html protein_coding_gene 0003677=DNA binding "IPR026095=Myb/SANT-like DNA-binding domain-containing protein, IPR003656=Zinc finger, BED-type" CG11560 16-Dec-15 2015_12 viable FBgn0034498 CG16868 http://flybase.net/reports/FBgn0034498.html protein_coding_gene "IPR029151=Periplasmic sensor domain-like, IPR002035=von Willebrand factor, type A" CG16868 16-Dec-15 2015_12 ENSDARG00000061590(LOC794807) ENSXETG00000020410(CACHD1) ENSMUSG00000028532(Cachd1) ENSG00000158966(CACHD1) "viable,visible" trichogen cell FBgn0065109 ppk11 pickpocket 11 http://flybase.net/reports/FBgn0065109.html "FBgn0032146, FBgn0054058" protein_coding_gene 0005272=sodium channel activity "0060025=regulation of synaptic activity, 0050914=sensory perception of salty taste, 0035002=liquid clearance, open tracheal system, 0006814=sodium ion transport" 0016021=integral component of membrane "pickpocket11, PPK11, CG4110, Pickpocket11, CG34058" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG34058 16-Dec-15 2015_12 "WBGene00000952(del-1),WBGene00012116(del-4)" "neurophysiology defective,viable,fertile,taste perception defective" "adult tracheal system,terminal organ" FBgn0033654 Sobp Sine oculis-binding protein http://flybase.net/reports/FBgn0033654.html protein_coding_gene 0008134=transcription factor binding 0048749=compound eye development "Sbp, CG8991" IPR026092=Retinoic acid-induced protein 2/sine oculis-binding protein homologue CG8991 16-Dec-15 2015_12 ENSXETG00000019261(SOBP) ENSMUSG00000038248(Sobp) ENSG00000112320(SOBP) eye FBgn0002395 l(3)93Fb lethal (3) 93Fb http://flybase.net/reports/FBgn0002395.html gene "l(3)er15, er15" 16-Dec-15 2015_12 "lethal,recessive" FBgn0005050 fft fused filament http://flybase.net/reports/FBgn0005050.html gene 16-Dec-15 2015_12 "female sterile,partially" dorsal appendage FBgn0003446 smt small thorax http://flybase.net/reports/FBgn0003446.html gene 16-Dec-15 2015_12 "visible,recessive,viable,reduced,male fertile,female fertile" "adult head,adult thorax,wing" FBgn0060818 l(3)S052713b lethal (3) S052713b http://flybase.net/reports/FBgn0060818.html gene 0527/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0053416 5SrRNA-ë¬:CR33416 5SrRNA-ë¬:CR33416 http://flybase.net/reports/FBgn0053416.html pseudogene_attribute CR33416 CR33416 16-Dec-15 2015_12 FBgn0013545 l(2)KE152 lethal (2) KE152 http://flybase.net/reports/FBgn0013545.html gene 16-Dec-15 2015_12 FBgn0044090 E(rst)D61 E(rst)D61 http://flybase.net/reports/FBgn0044090.html gene 0001745=compound eye morphogenesis D61 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0053301 CG33301 http://flybase.net/reports/FBgn0053301.html FBgn0032177 protein_coding_gene CG4791 "IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227" CG33301 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" FBgn0267480 CR45830 http://flybase.net/reports/FBgn0267480.html non_protein_coding_gene CR45830 16-Dec-15 2015_12 FBgn0262885 CR43240 http://flybase.net/reports/FBgn0262885.html pseudogene_attribute CR43240 16-Dec-15 2015_12 FBgn0264400 FCG-B http://flybase.net/reports/FBgn0264400.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0032877 CG2617 http://flybase.net/reports/FBgn0032877.html protein_coding_gene 0008270=zinc ion binding 38E.2 "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG2617 16-Dec-15 2015_12 ENSG00000173456(RNF26) viable FBgn0065148 l(3)SH079 lethal (3) SH079 http://flybase.net/reports/FBgn0065148.html gene l(2)SH3 079 16-Dec-15 2015_12 "lethal,recessive" FBgn0263765 CR43682 http://flybase.net/reports/FBgn0263765.html non_protein_coding_gene lincRNA.147 CR43682 16-Dec-15 2015_12 FBgn0267400 CR45762 http://flybase.net/reports/FBgn0267400.html non_protein_coding_gene CR45762 16-Dec-15 2015_12 FBgn0263895 l(3)B55 http://flybase.net/reports/FBgn0263895.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0052055 CG32055 http://flybase.net/reports/FBgn0052055.html FBgn0036077 protein_coding_gene 0005520=insulin-like growth factor binding 0016942=insulin-like growth factor binding protein complex "CG6590, CT20492" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG32055 16-Dec-15 2015_12 "ENSDARG00000062398,ENSDARG00000006636(sc:d0319),ENSDARG00000041912" ENSXETG00000015538(IGFALS) ENSG00000099769(IGFALS) viable FBgn0002854 Mst25F Male-specific RNA 25F http://flybase.net/reports/FBgn0002854.html gene mst323 16-Dec-15 2015_12 FBgn0052283 Drsl3 Drosomycin-like 3 http://flybase.net/reports/FBgn0052283.html FBgn0035433 protein_coding_gene "0006952=defense response, 0050832=defense response to fungus" 0005576=extracellular region "CG10813, Dro3, Drosomycin-3, Drosomycin-like E, Dro-3, drosomycin-3, dro3, Drs-lE, drosomycin, drosomycin-E, CT30310, Drosomycin 3, CG32283, Drosomycin3" "IPR003614=Knottin, scorpion toxin-like" CG32283 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" FBgn0037506 CG1287 http://flybase.net/reports/FBgn0037506.html FBgn0046308 protein_coding_gene BEST:GH03396 IPR006214=Bax inhibitor 1-related CG1287 16-Dec-15 2015_12 ENSDARG00000014573(ghitm) WBGene00019664(K11H12.8) ENSMUSG00000041028(Ghitm) ENSG00000165678(GHITM) viable FBgn0001999 l(2)36Ac lethal (2) 36Ac http://flybase.net/reports/FBgn0001999.html gene "l(2)HT-9, l(2L)HT-9" 16-Dec-15 2015_12 "lethal,recessive" FBgn0004169 up upheld http://flybase.net/reports/FBgn0004169.html "FBgn0001267, FBgn0003955, FBgn0047222" protein_coding_gene "0005509=calcium ion binding, 0005523=tropomyosin binding" "0007498=mesoderm development, 0007005=mitochondrion organization, 0006937=regulation of muscle contraction, 0046716=muscle cell cellular homeostasis, 0030240=skeletal muscle thin filament assembly, 0030239=myofibril assembly, 0006874=cellular calcium ion homeostasis, 0048644=muscle organ morphogenesis, 0045214=sarcomere organization" "0005861=troponin complex, 0005865=striated muscle thin filament" "tnT, troponin-T, cTNT, CG7107, FBgn0004169, TpnT, wupB, Tn-T, indented thorax, dro TnT, BcDNA:LD08591, TnT, troponin T, Troponin T, upheld2, DmTpnT, troponinT, troponin, int" "IPR027707=Troponin T, IPR001978=Troponin" CG7107 16-Dec-15 2015_12 "ENSDARG00000002988(tnnt2d),ENSDARG00000045822(tnnt2e),ENSDARG00000068457(tnnt3b),ENSDARG00000030270(tnnt3a),ENSDARG00000020610,ENSDARG00000032242(tnnt1),ENSDARG00000031920,ENSDARG00000037954(zgc:193865)" "WBGene00003495(mup-2),WBGene00006587(tnt-2),WBGene00006588(tnt-3),WBGene00006589(tnt-4)" "ENSXETG00000024952(Tnnt3),ENSXETG00000003199(TNNT1),ENSXETG00000017086(TNNT2)" "ENSMUSG00000061723(Tnnt3),ENSMUSG00000064179(Tnnt1),ENSMUSG00000026414(Tnnt2)" "ENSG00000130595(TNNT3),ENSG00000105048(TNNT1),ENSG00000118194(TNNT2)" " embryonic stage | mid & late , adult stage , pupal stage--pharate adult stage " organism

"flightless,recessive,visible,dominant,viable,fertile,jumping defective,developmental rate defective,locomotor behavior defective,semidominant,partially lethal - majority live,lethal" "indirect flight muscle,striated muscle thin filament,Z disc,M band,sarcomere,myofibril,sarcoplasmic reticulum,sarcomere | adult stage,wing,mesothoracic extracoxal depressor muscle 66,flight muscle,myosin filament & indirect flight muscle,striated muscle thin filament & indirect flight muscle,Z disc & indirect flight muscle,pupal cuticle,adult thorax,mitochondrion & flight muscle,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,striated muscle myosin thick filament" FBgn0264838 CR44046 http://flybase.net/reports/FBgn0264838.html non_protein_coding_gene CR44046 16-Dec-15 2015_12 FBgn0013438 demo defective modalities http://flybase.net/reports/FBgn0013438.html gene 16-Dec-15 2015_12 behavior defective FBgn0260648 Rrp40 http://flybase.net/reports/FBgn0260648.html "FBgn0064224, FBgn0051938" protein_coding_gene "0003723=RNA binding, 0000175=3'-5'-exoribonuclease activity" "0035167=larval lymph gland hemopoiesis, 0010468=regulation of gene expression, 0006364=rRNA processing" "0005737=cytoplasm, 0000176=nuclear exosome (RNase complex), 0000178=exosome (RNase complex)" "Rrp40, CG31938, dRrp40" "IPR022967=RNA-binding domain, S1, IPR026699=Exosome complex RNA-binding protein 1/RRP40/RRP4, IPR004088=K Homology domain, type 1, IPR012340=Nucleic acid-binding, OB-fold" CG31938 16-Dec-15 2015_12 ENSDARG00000029187(zgc:112345) YOL142W(RRP40) WBGene00010325(exos-3) ENSXETG00000013060(EXOSC3) ENSMUSG00000028322(Exosc3) ENSG00000107371(EXOSC3) DRSC00074 K -0.013193319 -0.228755582 -0.344364553 0.61125006 1.693259307 0.598479521 FBgn0266821 CR45283 http://flybase.net/reports/FBgn0266821.html non_protein_coding_gene CR45283 16-Dec-15 2015_12 FBgn0034066 CG8397 http://flybase.net/reports/FBgn0034066.html protein_coding_gene "0003779=actin binding, 0030246=carbohydrate binding" 0012505=endomembrane system "IPR013784=Carbohydrate-binding-like fold, IPR019008=Domain of unknown function DUF2012" CG8397 16-Dec-15 2015_12 ENSDARG00000012144(si:ch211-150c22.3) WBGene00016439(C35D10.1) ENSMUSG00000055943(2900064A13Rik) ENSG00000134153(C15orf24) viable FBgn0053443 5SrRNA:CR33443 5SrRNA:CR33443 http://flybase.net/reports/FBgn0053443.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33443 CR33443 16-Dec-15 2015_12 FBgn0000301 ch chubby http://flybase.net/reports/FBgn0000301.html gene 16-Dec-15 2015_12 "visible,recessive" "embryonic/first instar larval cuticle,embryonic/larval midgut" FBgn0028646 aralar1 aralar1 http://flybase.net/reports/FBgn0028646.html "FBgn0039772, FBgn0061423" protein_coding_gene "0005509=calcium ion binding, 0022857=transmembrane transporter activity" "0006839=mitochondrial transport, 0055085=transmembrane transport, 0006810=transport, 0042060=wound healing" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane, 0005811=lipid particle, 0005739=mitochondrion, 0016021=integral component of membrane" "BcDNA:GH07418, Aralar, Aralar1, aralar, DmAralar, CG2139" "IPR002048=EF-hand domain, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein, IPR011992=EF-hand domain pair" CG2139 16-Dec-15 2015_12 ENSDARG00000070172 WBGene00019326(K02F3.2) "ENSXETG00000016576(SLC25A13),ENSXETG00000018810(SLC25A12)" "ENSMUSG00000027010(Slc25a12),ENSMUSG00000015112(Slc25a13)" "ENSG00000115840(SLC25A12),ENSG00000004864(SLC25A13)" FBgn0034289 CG10910 http://flybase.net/reports/FBgn0034289.html protein_coding_gene CG10910 16-Dec-15 2015_12 "ENSXETG00000025694(),ENSXETG00000016846(),ENSXETG00000016465(),ENSXETG00000005606(),ENSXETG00000020193(),ENSXETG00000021626()" viable FBgn0036817 CG6865 http://flybase.net/reports/FBgn0036817.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP63 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG6865 16-Dec-15 2015_12 viable DRSC10732 I 1.110804 -1.604757084 -0.149844125 0.270809941 0.527378231 0.70782217 FBgn0011112 l(1)Q73 lethal (1) Q73 http://flybase.net/reports/FBgn0011112.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0259670 B0404 http://flybase.net/reports/FBgn0259670.html gene 16-Dec-15 2015_12 visible "wing vein L3,wing,wing vein,arista" FBgn0266217 CR44912 http://flybase.net/reports/FBgn0266217.html non_protein_coding_gene CR44912 16-Dec-15 2015_12 FBgn0036896 wnd wallenda http://flybase.net/reports/FBgn0036896.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0004709=MAP kinase kinase kinase activity, 0005524=ATP binding" "0007030=Golgi organization, 0046777=protein autophosphorylation, 0007283=spermatogenesis, 0006468=protein phosphorylation, 0048674=collateral sprouting of injured axon, 2000331=regulation of terminal button organization, 0000186=activation of MAPKK activity" 0030424=axon "Wnd, DLK, MAPKKK, Wallenda, DLK/ZPK, Wnd/DLK, CG8789, dual leucine zipper-bearing kinase" "IPR017419=Mitogen-activated protein kinase kinase kinase 12/13, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG8789 16-Dec-15 2015_12 "ENSDARG00000009493(si:ch211-45c16.2),ENSDARG00000042565(map3k12)" WBGene00002207(kin-25) "ENSMUSG00000023050(Map3k12),ENSMUSG00000033618(Map3k13)" "ENSG00000139625(MAP3K12),ENSG00000073803(MAP3K13)" "male sterile,neuroanatomy defective,RU486 conditional,lethal - all die before end of embryonic stage,some die during embryonic stage,conditional,viable,fertile" "NMJ bouton,RU486 conditional,neuromuscular junctionunspecified,bouton,dorsal multidendritic neuron ddaC,synapseppk.PG,segmental nerve,conditional" FBgn0259828 ifm(2)RS12 indirect flight muscle (2) RS12 http://flybase.net/reports/FBgn0259828.html gene 0007527=adult somatic muscle development 16-Dec-15 2015_12 viable indirect flight muscle FBgn0004410 het-rep2 heterochromatic repeat 2 http://flybase.net/reports/FBgn0004410.html repeat_region 16-Dec-15 2015_12 FBgn0266263 CR44958 http://flybase.net/reports/FBgn0266263.html non_protein_coding_gene CR44958 16-Dec-15 2015_12 FBgn0052759 CR32759 http://flybase.net/reports/FBgn0052759.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0013615 l(3)L1233 lethal (3) L1233 http://flybase.net/reports/FBgn0013615.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267528 CR45868 http://flybase.net/reports/FBgn0267528.html non_protein_coding_gene CR45868 16-Dec-15 2015_12 FBgn0053768 CG33768 http://flybase.net/reports/FBgn0053768.html FBgn0037173 protein_coding_gene CG14458 "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG33768 16-Dec-15 2015_12 viable FBgn0083946 lobo lost boys http://flybase.net/reports/FBgn0083946.html "FBan0013661, FBgn0039285, FBgn0039287" protein_coding_gene "0030317=sperm motility, 0046693=sperm storage" 0031514=motile cilium "CG34110, CG13662, CG13661" IPR002931=Transglutaminase-like CG34110 16-Dec-15 2015_12 ENSXETG00000013759(CCDC135) ENSMUSG00000031786(Ccdc135) ENSG00000159625(CCDC135) FBgn0011895 tRNA:K2:42Ed transfer RNA:lys2:42Ed http://flybase.net/reports/FBgn0011895.html "FBgn0003796, FBgn0011886, FBgn0050303, FBgn0060183" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033444=AAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K:CTT:AE002778-a, tRNAlys, chr2R.trna88-LysCTT, tRNA:K2, AE002778.trna1-LysCTT, tRNA[Lys][[2]], CR30303, tRNA:lys2:42Ed" CR30303 16-Dec-15 2015_12 FBgn0086217 Gc70 http://flybase.net/reports/FBgn0086217.html gene 0000776=kinetochore 16-Dec-15 2015_12 FBgn0015457 l(2)37CDb lethal (2) 37CDb http://flybase.net/reports/FBgn0015457.html gene l(2)E137 16-Dec-15 2015_12 "lethal,recessive" FBgn0052281 CG32281 http://flybase.net/reports/FBgn0052281.html FBgn0035408 protein_coding_gene "0009019=tRNA (guanine-N1-)-methyltransferase activity, 0008175=tRNA methyltransferase activity" "0006555=methionine metabolic process, 0006400=tRNA modification, 0030488=tRNA methylation" CG12032 "IPR030382=SAM-dependent methyltransferase TRM5/TYW2-type, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025792=tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic" CG32281 16-Dec-15 2015_12 "ENSDARG00000060765,ENSDARG00000069278(trmt5)" YHR070W(TRM5) ENSXETG00000014455(TRMT5) ENSMUSG00000034442(Trmt5) ENSG00000126814(TRMT5) viable FBgn0003313 sala spalt-adjacent http://flybase.net/reports/FBgn0003313.html FBgn0061400 protein_coding_gene 0007369=gastrulation "sal adjacent, spalt, nsal, CG4922, spalt accessory, sal, not-spalt, chr2L:11486634..11486740, BcDNA:RE40068" CG4922 16-Dec-15 2015_12 viable FBgn0003018 ota2 olfactory trap abnormal 2 http://flybase.net/reports/FBgn0003018.html gene 0007635=chemosensory behavior olfactory-trap-abnormal-2 16-Dec-15 2015_12 "smell perception defective,recessive,chemosensitive behavior defective" FBgn0003655 swa swallow http://flybase.net/reports/FBgn0003655.html FBgn0044557 protein_coding_gene "0003729=mRNA binding, 0045502=dynein binding" "0007015=actin filament organization, 0007317=regulation of pole plasm oskar mRNA localization, 0019094=pole plasm mRNA localization, 0045450=bicoid mRNA localization, 0008298=intracellular mRNA localization, 0008595=anterior/posterior axis specification, embryo" "sww, fs(1)M13C82, CG3429, fs(1)1502, fs(1)m44, fs(1)M11-999, fs(1)M44, Swa, Swallow, fs(1)1497, anon-WO0140519.70" CG3429 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S3 , adult stage | female , embryonic stage | blastoderm , embryonic stage | early , adult stage && oogenesis stage | stage S3-10B , embryonic stage | stage 1-3 " " oocyte | ubiquitous

, egg chamber

, organism

, nurse cell

, organism | ubiquitous

" " oogenesis stage | stage >=S5 , embryonic stage | cycle >=8 , oogenesis stage , embryonic stage | cycle <8 , embryonic stage | stage 12 , oogenesis stage && adult stage | female , embryonic stage | 0-6 hr " " oocyte

,

, ovary

" "viable,fertile,lethal,maternal effect,wild-type,recessive,female sterile,mitotic cell cycle defective" "gastrula embryo,maternal effect,embryonic/first instar larval cuticle,actin filament,stage S10 oocyte,stage S11 oocyte,stage S12 oocyte,stage S13 oocyte,stage S14 oocyte,embryonic head,embryonic abdomen,denticle belt,cleavage nucleus,syncytial blastoderm embryo,stage 5 embryo,larva,anterior,blastoderm embryo,centrosome | embryonic stage,pre-blastoderm embryo,aster,spindle,cell cycle,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,cleavage stage embryo" FBgn0060537 l(3)S100403 lethal (3) S100403 http://flybase.net/reports/FBgn0060537.html gene 1004/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0041754 head-peptide head peptide http://flybase.net/reports/FBgn0041754.html gene 16-Dec-15 2015_12 FBgn0033969 CG10202 http://flybase.net/reports/FBgn0033969.html FBgn0044732 protein_coding_gene "0004614=phosphoglucomutase activity, 0004615=phosphomannomutase activity" 0016052=carbohydrate catabolic process 0005829=cytosol anon-WO0140519.148 "IPR005844=Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR005845=Alpha-D-phosphohexomutase, alpha/beta/alpha domain II, IPR005846=Alpha-D-phosphohexomutase, alpha/beta/alpha domain III, IPR016055=Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III" CG10202 16-Dec-15 2015_12 "ENSDARG00000018178(pgm2),ENSDARG00000014704(pgm2l1)" YMR278W(PGM3) WBGene00012803(Y43F4B.5) ENSXETG00000022805(PGM2L1) "ENSMUSG00000030729(Pgm2l1),ENSMUSG00000029171(Pgm1)" "ENSG00000165434(PGM2L1),ENSG00000169299(PGM2)" viable FBgn0266860 CR45321 http://flybase.net/reports/FBgn0266860.html non_protein_coding_gene CR45321 16-Dec-15 2015_12 FBgn0260362 GSd472 http://flybase.net/reports/FBgn0260362.html gene 16-Dec-15 2015_12 lethal FBgn0021784 l(3)95BCa lethal (3) 95BCa http://flybase.net/reports/FBgn0021784.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011198 l(1)304-68 lethal (1) 304-68 http://flybase.net/reports/FBgn0011198.html FBgn0010203 gene 304-68 16-Dec-15 2015_12 "lethal,recessive" FBgn0039978 CG17455 http://flybase.net/reports/FBgn0039978.html protein_coding_gene 16-Dec-15 2015_12 FBgn0050409 CG30409 http://flybase.net/reports/FBgn0050409.html FBgn0034848 protein_coding_gene CG9872 CG30409 16-Dec-15 2015_12 "viable,fertile" FBgn0031948 CG7149 http://flybase.net/reports/FBgn0031948.html protein_coding_gene 0004142=diacylglycerol cholinephosphotransferase activity "0006909=phagocytosis, 0008654=phospholipid biosynthetic process" 0016020=membrane "cpt, diacylglycerol cholinephosphotransferase, dCCS3" "IPR014472=Choline/ethanolamine phosphotransferase, IPR000462=CDP-alcohol phosphatidyltransferase" CG7149 16-Dec-15 2015_12 ENSDARG00000060484(LOC557632) "YNL130C(CPT1),YHR123W(EPT1)" WBGene00018797(F54D7.2) ENSXETG00000003328(seli) ENSMUSG00000075703(Ept1) ENSG00000138018(EPT1) "viable,fertile" FBgn0016806 l(1)K8 lethal (1) K8 http://flybase.net/reports/FBgn0016806.html gene K8 16-Dec-15 2015_12 "lethal,recessive" FBgn0262034 CG42845 http://flybase.net/reports/FBgn0262034.html protein_coding_gene Chr2L_9349524_9350014.0 16-Dec-15 2015_12 FBgn0260040 siren4 siren 4 http://flybase.net/reports/FBgn0260040.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0052691 CG32691 http://flybase.net/reports/FBgn0052691.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0052425 CG32425 http://flybase.net/reports/FBgn0052425.html "FBgn0037002, FBgn0037006" protein_coding_gene "CG5100, CG15869" IPR000008=C2 domain CG32425 16-Dec-15 2015_12 "viable,fertile" FBgn0259922 Skadu Skadu http://flybase.net/reports/FBgn0259922.html protein_coding_gene 0003682=chromatin binding 0051276=chromosome organization "0000785=chromatin, 0005634=nucleus" "SKADU, CG42448, Skadu" "IPR000953=Chromo/chromo shadow domain, IPR008251=Chromo shadow domain, IPR016197=Chromo domain-like" CG42448 16-Dec-15 2015_12 FBgn0033446 CG1648 http://flybase.net/reports/FBgn0033446.html protein_coding_gene 0005811=lipid particle CG1648 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0283456 EC3-9 Enhancer of CCT 3-9 http://flybase.net/reports/FBgn0283456.html gene 16-Dec-15 2015_12 FBgn0031912 CG5261 http://flybase.net/reports/FBgn0031912.html "FBgn0062231, FBgn0062641" protein_coding_gene 0004742=dihydrolipoyllysine-residue acetyltransferase activity 0006086=acetyl-CoA biosynthetic process from pyruvate "0005967=mitochondrial pyruvate dehydrogenase complex, 0005811=lipid particle" "EP(2)0816, EP816, DLAT, anon-WO0118547.121, Dihydrolipoyllysine-residue acetyltransferase" "IPR023213=Chloramphenicol acetyltransferase-like domain, IPR011053=Single hybrid motif, IPR001078=2-oxoacid dehydrogenase acyltransferase, catalytic domain, IPR000089=Biotin/lipoyl attachment, IPR006257=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, IPR003016=2-oxo acid dehydrogenase, lipoyl-binding site" CG5261 16-Dec-15 2015_12 ENSDARG00000015918(dlat) YNL071W(LAT1) WBGene00009082(F23B12.5) ENSXETG00000010198(TGas088f15.1) ENSMUSG00000000168(Dlat) ENSG00000150768(DLAT) wild-type "wing,posterior compartment" FBgn0045478 Gr64b Gustatory receptor 64b http://flybase.net/reports/FBgn0045478.html "FBgn0035485, FBgn0052257, FBgn0061837, FBgn0063608" protein_coding_gene "0033041=sweet taste receptor activity, 0008527=taste receptor activity" "0050912=detection of chemical stimulus involved in sensory perception of taste, 0050909=sensory perception of taste, 0050916=sensory perception of sweet taste" 0016021=integral component of membrane "Gr64, CG14986, GR64b, Dmel64b, anon-WO0118547.604, CG32257" IPR009318=Gustatory receptor CG32257 16-Dec-15 2015_12 WBGene00001804(gur-3) "taste perception defective,viable" FBgn0267045 CG45489 http://flybase.net/reports/FBgn0267045.html protein_coding_gene CG45489 16-Dec-15 2015_12 FBgn0002832 ms(2)E11 male sterile (2) E11 http://flybase.net/reports/FBgn0002832.html gene "ms2.11, ms(2)2.11" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0002538 Lcp7 Larval cuticle protein 7 http://flybase.net/reports/FBgn0002538.html gene 0008010=structural constituent of chitin-based larval cuticle LCP7 16-Dec-15 2015_12 FBgn0261020 wol wollknaeuel http://flybase.net/reports/FBgn0261020.html "FBgn0069072, FBgn0032012" protein_coding_gene 0004581=dolichyl-phosphate beta-glucosyltransferase activity "0006493=protein O-linked glycosylation, 0007030=Golgi organization, 0009880=embryonic pattern specification, 0007029=endoplasmic reticulum organization, 0007009=plasma membrane organization, 0040003=chitin-based cuticle development, 0019991=septate junction assembly, 0007379=segment specification, 0006487=protein N-linked glycosylation" 0005783=endoplasmic reticulum "Wol, alg5, dAlg5, CG7870, ALG5, wollknauel" "IPR001173=Glycosyltransferase 2-like, IPR029044=Nucleotide-diphospho-sugar transferases" CG7870 16-Dec-15 2015_12 ENSDARG00000061235(alg5) YPL227C(ALG5) WBGene00019276(H43I07.3) ENSXETG00000001813(alg5) ENSMUSG00000036632(Alg5) ENSG00000120697(ALG5) FBgn0037539 CG10435 http://flybase.net/reports/FBgn0037539.html protein_coding_gene "IPR015940=Ubiquitin-associated domain, IPR009060=UBA-like, IPR023340=UMA domain" CG10435 16-Dec-15 2015_12 ENSXETG00000002160(ubap1) ENSMUSG00000028437(Ubap1) ENSG00000165006(UBAP1) "viable,fertile,visible" "heart primordium,trichogen cell" DRSC25312 K 0.154923221 0.417020159 1.184724224 -0.620809161 -0.709173166 -2.020362448 FBgn0029659 CG16782 http://flybase.net/reports/FBgn0029659.html protein_coding_gene CG16782 16-Dec-15 2015_12 "viable,fertile" FBgn0264487 CG43895 http://flybase.net/reports/FBgn0264487.html protein_coding_gene CG43895 16-Dec-15 2015_12 FBgn0065677 l(2)SH0674 lethal (2) SH0674 http://flybase.net/reports/FBgn0065677.html gene l(2)SH2 0674 16-Dec-15 2015_12 "lethal,recessive" FBgn0029761 SK small conductance calcium-activated potassium channel http://flybase.net/reports/FBgn0029761.html "FBgn0029758, FBgn0029760, FBgn0062493" protein_coding_gene "0015269=calcium-activated potassium channel activity, 0009881=photoreceptor activity, 0005516=calmodulin binding, 0016286=small conductance calcium-activated potassium channel activity" "0006813=potassium ion transport, 0016057=regulation of membrane potential in photoreceptor cell" 0016021=integral component of membrane "CG12733, BcDNA:GM01744, CG10706, dSK, Sk, CG4179" "IPR015449=Potassium channel, calcium-activated, SK, IPR013099=Potassium channel domain, IPR004178=Calmodulin-binding domain" CG10706 16-Dec-15 2015_12 "ENSDARG00000061812,ENSDARG00000014939(LOC564698),ENSDARG00000023546(kcnn1),ENSDARG00000019753(LOC570138)" WBGene00008570(kcnl-2) "ENSXETG00000021518(KCNN2),ENSXETG00000013542(KCNN1)" "ENSMUSG00000000794(Kcnn3),ENSMUSG00000054477(Kcnn2),ENSMUSG00000002908(Kcnn1)" "ENSG00000143603(KCNN3),ENSG00000080709(KCNN2),ENSG00000105642(KCNN1)" "viable,fertile,immune response defective,neurophysiology defective" photoreceptor cell FBgn0005337 Pub Pub http://flybase.net/reports/FBgn0005337.html gene 16-Dec-15 2015_12 "eye,ommatidium" FBgn0050323 CG30323 http://flybase.net/reports/FBgn0050323.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG30323 16-Dec-15 2015_12 viable FBgn0034157 resilin resilin http://flybase.net/reports/FBgn0034157.html protein_coding_gene "0030023=extracellular matrix constituent conferring elasticity, 0008010=structural constituent of chitin-based larval cuticle, 0008061=chitin binding, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development "0032992=protein-carbohydrate complex, 0031012=extracellular matrix" "CG15920, Resilin" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG15920 16-Dec-15 2015_12 FBgn0267917 CR46198 http://flybase.net/reports/FBgn0267917.html non_protein_coding_gene lincRNA.439 CR46198 16-Dec-15 2015_12 FBgn0011331 l(3)j2C4 lethal (3) j2C4 http://flybase.net/reports/FBgn0011331.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029718 mRpL30 mitochondrial ribosomal protein L30 http://flybase.net/reports/FBgn0029718.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "CG7038, L30, Mitochondrial ribosomal protein L30, mRPL30" "IPR016082=Ribosomal protein L30, ferredoxin-like fold domain" CG7038 16-Dec-15 2015_12 ENSDARG00000069850(zgc:112089) WBGene00021021(W04B5.4) ENSXETG00000026571(mrpl30) ENSMUSG00000026087(Mrpl30) ENSG00000185414(MRPL30) "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell DRSC18416 K -1.245690207 -0.53606951 -0.441663212 -1.089366861 1.218389331 2.641198684 FBgn0065841 l(2)SH0324 lethal (2) SH0324 http://flybase.net/reports/FBgn0065841.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040643 CG12566 http://flybase.net/reports/FBgn0040643.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065819 l(2)SH0373 lethal (2) SH0373 http://flybase.net/reports/FBgn0065819.html gene l(2)SH2 0373 16-Dec-15 2015_12 "lethal,recessive" FBgn0265869 CR44658 http://flybase.net/reports/FBgn0265869.html non_protein_coding_gene lincRNA.994 CR44658 16-Dec-15 2015_12 FBgn0043591 E(roDOM)50 E(roDOM)50 http://flybase.net/reports/FBgn0043591.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0029885 CG3224 http://flybase.net/reports/FBgn0029885.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0022008=neurogenesis unnamed "IPR015880=Zinc finger, C2H2-like, IPR003604=Zinc finger, U1-type, IPR007087=Zinc finger, C2H2, IPR022755=Zinc finger, double-stranded RNA binding" CG3224 16-Dec-15 2015_12 ENSDARG00000044102(znf593) YLR074C(BUD20) WBGene00013236(Y56A3A.18) ENSXETG00000009189(ZNF593) ENSMUSG00000028840(Zfp593) ENSG00000142684(ZNF593) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0052525 tRNA:CR32525 transfer RNA:CR32525 http://flybase.net/reports/FBgn0052525.html "FBgn0012015, FBgn0060008" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR32525, tRNA:Y:GTA:AE002620-b, chrX.trna17-TyrGTA, tRNA[Tyr][[1gamma]], tRNA:tyr1:19F, tRNA:Y1:19F, transfer RNA:tyr1:19F, AE002620.trna4-TyrGTA" CR32525 16-Dec-15 2015_12 FBgn0264362 CG43814 http://flybase.net/reports/FBgn0264362.html protein_coding_gene CG43814 16-Dec-15 2015_12 FBgn0065523 l(2)SH1124 lethal (2) SH1124 http://flybase.net/reports/FBgn0065523.html gene l(2)SH2 1124 16-Dec-15 2015_12 "lethal,recessive" FBgn0022401 Gase1 Gastric serine protease 1 http://flybase.net/reports/FBgn0022401.html gene 0008236=serine-type peptidase activity 16-Dec-15 2015_12 FBgn0259751 ms(3)Z3741 http://flybase.net/reports/FBgn0259751.html gene "0007283=spermatogenesis, 0051276=chromosome organization" "168-112, ms(3)168-112, 127-109, ms(3)127-109" 16-Dec-15 2015_12 "male sterile,viable" "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,aster" FBgn0266888 CR45349 http://flybase.net/reports/FBgn0266888.html non_protein_coding_gene CR45349 16-Dec-15 2015_12 FBgn0040022 Set1 SET domain containing 1 http://flybase.net/reports/FBgn0040022.html "FBgn0040021, FBan0040351" protein_coding_gene "0042800=histone methyltransferase activity (H3-K4 specific), 0018024=histone-lysine N-methyltransferase activity, 0003676=nucleic acid binding, 0000166=nucleotide binding" "0006338=chromatin remodeling, 0044648=histone H3-K4 dimethylation, 0046427=positive regulation of JAK-STAT cascade, 0051568=histone H3-K4 methylation, 0080182=histone H3-K4 trimethylation" "0005700=polytene chromosome, 0000791=euchromatin, 0048188=Set1C/COMPASS complex, 0035327=transcriptionally active chromatin, 0005634=nucleus" "CG40351, dSet1, SET1, dset1, lethal 5, aaf45425 Dm, CG17395, l(3)h5, CG17396" "IPR001214=SET domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain, IPR024657=COMPASS complex Set1 subunit, N-SET domain, IPR003616=Post-SET domain" CG40351 16-Dec-15 2015_12 "ENSDARG00000060847(setd1ba),ENSDARG00000044934" YHR119W(SET1) WBGene00004782(set-2) "ENSXETG00000003760(SETD1B),ENSXETG00000001921(SETD1A)" ENSMUSG00000042308(Setd1a) ENSG00000099381(SETD1A) "viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal,visible" trichogen cell DRSC20930 E -0.9257417 -1.246128966 -1.742146401 -0.132087904 FBgn0025874 Meics Meiotic central spindle http://flybase.net/reports/FBgn0025874.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0005876=spindle microtubule, 0005737=cytoplasm, 0005819=spindle, 0005634=nucleus" "CG8474, zinc-finger-motif-protein" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG8474 16-Dec-15 2015_12 YPR186C(PZF1) WBGene00009448(zfp-2) DRSC29541 K -0.434256174 -1.204638876 0.274886343 -0.369815417 -1.784835121 -0.135515699 FBgn0005763 l(1)TK410 lethal (1) TK410 http://flybase.net/reports/FBgn0005763.html gene l410 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0024197 quag quagmire http://flybase.net/reports/FBgn0024197.html gene 0030036=actin cytoskeleton organization l(3)05089 16-Dec-15 2015_12 "lethal,recessive,maternal effect,partially lethal - majority die" "embryonic/first instar larval cuticle,maternal effect" FBgn0015964 l(2)46DEb lethal (2) 46DEb http://flybase.net/reports/FBgn0015964.html gene group 6 16-Dec-15 2015_12 "lethal,recessive" FBgn0002549 lgh longhaired http://flybase.net/reports/FBgn0002549.html gene 16-Dec-15 2015_12 "male sterile,visible,viable,male,poor,body color defective" "adult head,adult thorax,microchaeta,macrochaeta,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7" FBgn0084037 CG41477 http://flybase.net/reports/FBgn0084037.html FBan0041477 protein_coding_gene 16-Dec-15 2015_12 FBgn0019780 l(1)29 lethal (1) 29 http://flybase.net/reports/FBgn0019780.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010409 RpL18A Ribosomal protein L18A http://flybase.net/reports/FBgn0010409.html FBgn0025284 protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0006412=translation, 0051298=centrosome duplication" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "anon-EST:Posey75, RpL18a, ribosomal protein L18a, RPL18a, CG6510, L18, L18A, L18a" "IPR028877=50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a, IPR023573=Ribosomal protein L18a/LX, IPR021138=60S ribosomal protein L18a/ L20, eukaryotes" CG6510 16-Dec-15 2015_12 ENSDARG00000025073(rpl18a) "YOR312C(RPL20B),YMR242C(RPL20A)" WBGene00004432(rpl-20) ENSXETG00000021667(RPL18A) "ENSMUSG00000045128(Rpl18a),ENSMUSG00000066620(Gm4883)" "ENSG00000105640(RPL18A),ENSG00000217644" DRSC07538 IEK -2.134900736 -1.493940415 -2.891120101 -5.031504533 1.905558227 3.264631192 FBgn0029888 ND-ASHI NADH dehydrogenase (ubiquinone) ASHI subunit http://flybase.net/reports/FBgn0029888.html protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH:ubiquinone oxidoreductase ASHI subunit, NIAM, NADH-ubiquinone oxidoreductase ASHI subunit, NADH ubiquinone oxidoreductase ASHI, CG3192" "IPR008699=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, IPR016551=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa" CG3192 16-Dec-15 2015_12 ENSDARG00000010113(ndufb8) WBGene00013094(Y51H1A.3) ENSMUSG00000025204(Ndufb8) ENSG00000166136(NDUFB8) "viable,visible" trichogen cell FBgn0036870 CG14095 http://flybase.net/reports/FBgn0036870.html protein_coding_gene CG14095 16-Dec-15 2015_12 viable FBgn0002267 l(3)69Af lethal (3) 69Af http://flybase.net/reports/FBgn0002267.html gene "rose-gespleten region interval 29, rsg29, l(3)rsg29" 16-Dec-15 2015_12 lethal FBgn0005509 l(2)24EFg lethal (2) 24EFg http://flybase.net/reports/FBgn0005509.html gene l(2)Gr.VII 16-Dec-15 2015_12 "lethal,recessive" FBgn0263110 CG43367 http://flybase.net/reports/FBgn0263110.html "FBgn0035507, FBgn0035509, FBgn0035514" protein_coding_gene 0016230=sphingomyelin phosphodiesterase activator activity "CG1308, CG1295, CG1332" "IPR000409=BEACH domain, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR017986=WD40-repeat-containing domain, IPR023362=PH-BEACH domain" CG43367 16-Dec-15 2015_12 "ENSDARG00000044955,ENSDARG00000032436" "ENSXETG00000022086(NBEAL1),ENSXETG00000021305(NBEAL2)" ENSMUSG00000073664 "ENSG00000144426(NBEAL1),ENSG00000160796(NBEAL2)" FBgn0060639 l(3)S084305b lethal (3) S084305b http://flybase.net/reports/FBgn0060639.html gene 0843/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0041126 l(2)45Ak lethal (2) 45Ak http://flybase.net/reports/FBgn0041126.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0043577 PGRP-SB2 PGRP-SB2 http://flybase.net/reports/FBgn0043577.html FBgn0036657 protein_coding_gene "0008270=zinc ion binding, 0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity" "0006955=immune response, 0006952=defense response, 0009253=peptidoglycan catabolic process" "0005887=integral component of plasma membrane, 0005576=extracellular region" "CG9697, PGRP-SB" "IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein, IPR017331=Peptidoglycan recognition protein, PGRP-S" CG9697 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0037850 CG14695 http://flybase.net/reports/FBgn0037850.html protein_coding_gene CG14695 16-Dec-15 2015_12 "viable,fertile" FBgn0260226 CG42500 http://flybase.net/reports/FBgn0260226.html protein_coding_gene CG14359 IPR013172=Immune-induced protein Dim CG42500 16-Dec-15 2015_12 FBgn0030070 CG3898 http://flybase.net/reports/FBgn0030070.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014934 anon-87Ec anon-87Ec http://flybase.net/reports/FBgn0014934.html gene "Transcription unit C, C" 16-Dec-15 2015_12 FBgn0003885 ë±Tub84D ë±-Tubulin at 84D http://flybase.net/reports/FBgn0003885.html protein_coding_gene "0017022=myosin binding, 0005525=GTP binding, 0005200=structural constituent of cytoskeleton, 0003924=GTPase activity" "0051258=protein polymerization, 0000281=mitotic cytokinesis, 0007017=microtubule-based process" "0045298=tubulin complex, 0005874=microtubule, 0005811=lipid particle, 0048471=perinuclear region of cytoplasm" "alphaTUB, alpha-Tubulin, alphaTub84D, alpha tubulin, alphatubulin, CG2512, alpha-tub84D, Tub, tubulin alpha3, alpha-tubulin at 84D, alpha3, T, alpha-Tubulin at 84D, alphaTUB84D, alpha-tub, alpha3t, alphaTub3, D.m.ALPHA-84D, Tubulin at 84D, alpha-Tub, aTub84D, alpha84D, alphaTub, Tubulin-alpha3, alpha-tubulin, alphaTub84, ALPHA 84D, alphaT, alphaTubulin 84D, tubulin, 3t, alpha-Tub84D, Tubulin alpha-3 chain, DTA4" "IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR000217=Tubulin, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR008280=Tubulin/FtsZ, C-terminal, IPR017975=Tubulin, conserved site, IPR002452=Alpha tubulin" CG2512 16-Dec-15 2015_12 "ENSDARG00000001889(tuba1l2),ENSDARG00000055216(tuba1l),ENSDARG00000036700(LOC795591),ENSDARG00000045014(tuba2)" "YML085C(TUB1),YML124C(TUB3)" WBGene00003175(mec-12) "ENSXETG00000011186(TUBA1A),ENSXETG00000011185(TUBA1B),ENSXETG00000019254(tuba3),ENSXETG00000019246(tuba3)" "ENSMUSG00000072235(Tuba1a),ENSMUSG00000067702(Tuba3a),ENSMUSG00000067338(Tuba3b),ENSMUSG00000023004(Tuba1b),ENSMUSG00000043091(Tuba1c)" "ENSG00000198033(TUBA3C),ENSG00000075886(TUBA3D),ENSG00000167552(TUBA1A),ENSG00000123416(TUBA1B),ENSG00000167553(TUBA1C),ENSG00000152086(TUBA3E)" " pupal stage , embryonic stage | 6-12 hr , larval stage | second instar , embryonic stage | 2-18 hr , prepupal stage , embryonic stage | 0-3 hr , larval stage | first instar , oogenesis stage && adult stage | female , larval stage | third instar , adult stage | female " ovary

" embryonic stage | 10 hr , embryonic stage , embryonic stage | early " " longitudinal connective

, epidermis

, embryonic/larval esophagus

, embryonic central nervous system

, ventral nerve cord commissure

" DRSC12623 IEK 3.122311164 -1.305856428 2.763135809 -2.032425659 2.139000413 0.819453992 FBgn0042105 CG18748 http://flybase.net/reports/FBgn0042105.html protein_coding_gene CR18748 "IPR011022=Arrestin C-terminal-like domain, IPR014756=Immunoglobulin E-set, IPR011021=Arrestin-like, N-terminal" CG18748 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" "ENSXETG00000013606(ARRDC2),ENSXETG00000018085(arrdc3),ENSXETG00000002108(ARRDC4),ENSXETG00000011050(TXNIP)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" "ENSG00000105643(ARRDC2),ENSG00000113369(ARRDC3),ENSG00000140450(ARRDC4),ENSG00000117289(TXNIP)" viable FBgn0032522 CG16848 http://flybase.net/reports/FBgn0032522.html protein_coding_gene 0003919=FMN adenylyltransferase activity 0008152=metabolic process FBgn0032522 "IPR002500=Phosphoadenosine phosphosulphate reductase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG16848 16-Dec-15 2015_12 YDL045C(FAD1) viable FBgn0013497 l(1)14Ag lethal (1) 14Ag http://flybase.net/reports/FBgn0013497.html gene "II, l(1)II, l(1)13Fj" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001571 l(1)52 lethal (1) 52 http://flybase.net/reports/FBgn0001571.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" "nervous system,testis,imaginal disc,embryonic/larval salivary gland" FBgn0070007 BG01485 BG01485 http://flybase.net/reports/FBgn0070007.html gene 16-Dec-15 2015_12 stress response defective FBgn0052982 CG32982 http://flybase.net/reports/FBgn0052982.html "FBgn0032097, FBgn0032098, FBgn0032099" protein_coding_gene "CG9584, CG9585, CG18566" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG32982 16-Dec-15 2015_12 viable FBgn0038122 CG8138 http://flybase.net/reports/FBgn0038122.html protein_coding_gene IPR027887=Protein of unknown function DUF4464 CG8138 16-Dec-15 2015_12 ENSXETG00000021537(C4orf22) ENSMUSG00000057816(1700007G11Rik) ENSG00000197826(C4orf22) "viable,fertile" FBgn0053783 CG33783 http://flybase.net/reports/FBgn0053783.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33783 16-Dec-15 2015_12 FBgn0026399 Or85e Odorant receptor 85e http://flybase.net/reports/FBgn0026399.html protein_coding_gene "0005549=odorant binding, 0004888=transmembrane signaling receptor activity, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "OR85e, DOR104, dor104, 85e, CR9700, Dor104, CG9700, Odorant receptor 104, Or104, DOR85e, 85B.1, OR55" "IPR004117=Olfactory receptor, Drosophila" CG9700 16-Dec-15 2015_12 adult stage sensory neuron &&of maxillary palp sense organ

FBgn0085456 CG34427 http://flybase.net/reports/FBgn0085456.html "FBan0013307, FBgn0035930" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG13307 IPR002557=Chitin binding domain CG34427 16-Dec-15 2015_12 FBgn0013616 l(3)L2290 lethal (3) L2290 http://flybase.net/reports/FBgn0013616.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267142 CR45582 http://flybase.net/reports/FBgn0267142.html non_protein_coding_gene CR45582 16-Dec-15 2015_12 FBgn0036763 CG7441 http://flybase.net/reports/FBgn0036763.html FBgn0046314 protein_coding_gene "0005524=ATP binding, 0004830=tryptophan-tRNA ligase activity" 0006436=tryptophanyl-tRNA aminoacylation 0005737=cytoplasm "BEST:CK01295, GH31" "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR002306=Tryptophan-tRNA ligase, IPR024109=Tryptophan-tRNA ligase, bacterial-type, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR002305=Aminoacyl-tRNA synthetase, class Ic" CG7441 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0002680 mat(2)syn-H maternal effect syncytial blastoderm arrest H http://flybase.net/reports/FBgn0002680.html gene "0007279=pole cell formation, 0007349=cellularization" mat(2)synRE48 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0069316 X-187-38 X-187-38 http://flybase.net/reports/FBgn0069316.html gene 16-Dec-15 2015_12 FBgn0267628 CR45966 http://flybase.net/reports/FBgn0267628.html non_protein_coding_gene CR45966 16-Dec-15 2015_12 FBgn0014054 Su(tor)2-341 Su(tor)2-341 http://flybase.net/reports/FBgn0014054.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0050296 RIC-3 http://flybase.net/reports/FBgn0050296.html "FBgn0034574, FBgn0034575" protein_coding_gene 0051082=unfolded protein binding "0061077=chaperone-mediated protein folding, 0022417=protein maturation by protein folding" 0016021=integral component of membrane "CG30296, RIC-3, CG9349, CG15652, DmRIC-3" CG30296 16-Dec-15 2015_12 WBGene00004363(ric-3) DRSC04543 IK -0.674210135 -1.551179843 0.724130224 -0.002200115 -1.630441604 -1.132259193 FBgn0015579 2.1 2.1 http://flybase.net/reports/FBgn0015579.html gene 0005634=nucleus 16-Dec-15 2015_12 FBgn0002726 Mfcp Myofibrillar contractile protein http://flybase.net/reports/FBgn0002726.html gene 16-Dec-15 2015_12 FBgn0043005 prt portabella http://flybase.net/reports/FBgn0043005.html protein_coding_gene 0005276=vesicular hydrogen:amino acid antiporter activity "0008355=olfactory learning, 0060179=male mating behavior, 0055085=transmembrane transport" "0016021=integral component of membrane, 0008021=synaptic vesicle" "portabella, CG10251" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG10251 16-Dec-15 2015_12 "viable,fertile,learning defective,courtship behavior defective,male,mating defective" sex comb tooth FBgn0039965 CG13865 http://flybase.net/reports/FBgn0039965.html "FBan0013865, FBgn0058301" protein_coding_gene "FBgn0039965, CG40301" "IPR006597=Sel1-like repeat, IPR011990=Tetratricopeptide-like helical domain" CG13865 16-Dec-15 2015_12 ENSDARG00000019355(si:ch211-11m18.2) WBGene00013925(ZK20.4) ENSXETG00000008063(C1orf163) ENSMUSG00000048351(2010305A19Rik) ENSG00000162377(SELRC1) viable DRSC20967 EK 1.153889953 -0.211714862 1.99433468 0.495399308 1.585950296 1.893799129 FBgn0039908 Asator Asator http://flybase.net/reports/FBgn0039908.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "0005737=cytoplasm, 0005819=spindle" "CG11533, CK I, CKI-like" "IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain" CG11533 16-Dec-15 2015_12 "ENSMUSG00000027284(Ttbk2),ENSMUSG00000015599(Ttbk1)" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" FBgn0032147 IP3K1 "Inositol 1,4,5-triphosphate kinase 1" http://flybase.net/reports/FBgn0032147.html "FBgn0043966, FBgn0062182" protein_coding_gene "0008440=inositol-1,4,5-trisphosphate 3-kinase activity, 0005516=calmodulin binding" 0006979=response to oxidative stress 0005737=cytoplasm "D-IP3K1, dmIP3Kalpha, IP3 kinase 1, IP3KI, IP[[3]]K-1, Inositol 1,4,5-triphosphate kinase1, dmIP[[3]]Kalpha, UY530, CG4026, anon-WO0118547.189" IPR005522=Inositol polyphosphate kinase CG4026 16-Dec-15 2015_12 "ENSDARG00000042856(LOC564528),ENSDARG00000010059(si:ch211-97m8.1),ENSDARG00000002994(itpkc),ENSDARG00000053488(LOC100333120),ENSDARG00000067741(si:dkey-233h2.3)" WBGene00002979(lfe-2) "viable,fertile,oxidative stress response defective,chemical sensitive,chemical resistant" Malpighian tubule FBgn0041744 l(1)em5 lethal (1) em5 http://flybase.net/reports/FBgn0041744.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052082 CG32082 http://flybase.net/reports/FBgn0052082.html "FBgn0036140, FBgn0062175" protein_coding_gene "0005543=phospholipid binding, 0004871=signal transducer activity" "0061024=membrane organization, 0007009=plasma membrane organization" "CG7624, anon-WO0118547.199" "IPR027681=I-BAR domain containing protein IRSp53/IRTKS/Pinkbar, IPR001452=SH3 domain, IPR013606=IMD/I-BAR domain" CG32082 16-Dec-15 2015_12 "ENSDARG00000017785(zgc:158689),ENSDARG00000062799(zgc:136827),ENSDARG00000060587,ENSDARG00000029305(baiap2l1a),ENSDARG00000031119(baiap2l1b)" "YBL085W(BOI1),YER114C(BOI2)" "ENSXETG00000013408(BAIAP2),ENSXETG00000004593(),ENSXETG00000024036(BAIAP2L1)" "ENSMUSG00000025372(Baiap2),ENSMUSG00000038859(Baiap2l1)" "ENSG00000006453(BAIAP2L1),ENSG00000175866(BAIAP2),ENSG00000128298(BAIAP2L2)" FBgn0033166 Eaf ELL-associated factor http://flybase.net/reports/FBgn0033166.html FBgn0033163 protein_coding_gene "0043620=regulation of DNA-templated transcription in response to stress, 0042060=wound healing" "0032783=ELL-EAF complex, 0005654=nucleoplasm" "CG1706, Eaf, LD35207, CG11166, dELL-associated factor, EP(2)2475, dEaf" "IPR019194=Transcription elognation factor Eaf, N-terminal, IPR027093=EAF family" CG11166 16-Dec-15 2015_12 "ENSDARG00000070795(eaf1),ENSDARG00000010432(eaf2)" WBGene00017011(eaf-1) "ENSXETG00000022009(EAF1),ENSXETG00000000002(EAF2)" "ENSG00000145088(EAF2),ENSG00000144597(EAF1)" "lethal,viable,visible" trichogen cell FBgn0001662 l(1)E25 lethal (1) E25 http://flybase.net/reports/FBgn0001662.html gene l(1)E25[ts] 16-Dec-15 2015_12 "lethal,polyphasic,maternal effect" FBgn0052677 X11Lë_ X11Lë_ http://flybase.net/reports/FBgn0052677.html "FBgn0030225, FBgn0030226" protein_coding_gene 0001540=beta-amyloid binding 0072657=protein localization to membrane "X11Lbeta, X11B, CG32677, Dmint2, CG1852, CG1861, x11Lbeta" "IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001478=PDZ domain" CG32677 16-Dec-15 2015_12 "ENSDARG00000060639(apba2),ENSDARG00000014105(LOC100003938),ENSDARG00000063314" WBGene00002999(lin-10) ENSXETG00000016503(APBA2) "ENSMUSG00000024897(Apba1),ENSMUSG00000030519(Apba2)" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell FBgn0052040 CG32040 http://flybase.net/reports/FBgn0052040.html protein_coding_gene CG32040 16-Dec-15 2015_12 viable FBgn0043896 im(1)179 im(1)179 http://flybase.net/reports/FBgn0043896.html gene 0006955=immune response FB179 16-Dec-15 2015_12 FBgn0064190 beb bebra http://flybase.net/reports/FBgn0064190.html gene 0007315=pole plasm assembly 16-Dec-15 2015_12 "pole cell,germline clone,maternal effect" FBgn0028343 Ankle2 ANKLE2 ortholog http://flybase.net/reports/FBgn0028343.html "FBgn0028328, FBgn0030845, FBgn0066835, FBgn0066836, FBgn0066837" protein_coding_gene "0000902=cell morphogenesis, 0022008=neurogenesis" "0005783=endoplasmic reticulum, 0005737=cytoplasm, 0012505=endomembrane system" "l(1)G0316, l(1)G0222, lethal (1) G0222, dAnkle2, anon-WO03040301.179, anon-WO03040301.175, anon-WO03040301.177, CG8465" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG8465 16-Dec-15 2015_12 ENSXETG00000023848(ANKLE2) ENSMUSG00000029501(Ankle2) ENSG00000176915(ANKLE2) "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0035486 Gr64d Gustatory receptor 64d http://flybase.net/reports/FBgn0035486.html FBgn0053157 protein_coding_gene "0008527=taste receptor activity, 0033041=sweet taste receptor activity" "0050916=sensory perception of sweet taste, 0050909=sensory perception of taste, 0050912=detection of chemical stimulus involved in sensory perception of taste" 0016021=integral component of membrane "Dmel64d, CG33157, GR64d, Gr64, CG14987" IPR009318=Gustatory receptor CG14987 16-Dec-15 2015_12 WBGene00001804(gur-3) taste perception defective FBgn0027200 l(1)H21 lethal (1) H21 http://flybase.net/reports/FBgn0027200.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0267991 CR46258 http://flybase.net/reports/FBgn0267991.html non_protein_coding_gene CR46258 16-Dec-15 2015_12 FBgn0029706 CG3626 http://flybase.net/reports/FBgn0029706.html protein_coding_gene "0016491=oxidoreductase activity, 0019909=[pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity" 0055114=oxidation-reduction process 0019910=mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex "IPR027266=GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1, IPR013977=Glycine cleavage T-protein, C-terminal barrel domain, IPR006076=FAD dependent oxidoreductase, IPR029043=Glycine cleavage T-protein/YgfZ, C-terminal domain, IPR006222=Glycine cleavage T-protein-like, N-terminal" CG3626 16-Dec-15 2015_12 ENSDARG00000023113(ypel5) WBGene00013718(Y106G6H.5) ENSXETG00000007670() ENSMUSG00000033624(4930402E16Rik) ENSG00000090857(PDPR) "viable,fertile" FBgn0261112 APP-BP1 ë_-Amyloid precursor protein binding protein 1 http://flybase.net/reports/FBgn0261112.html "FBgn0086218, FBgn0036127, FBgn0063280, FBgn0046307, FBgn0044646" protein_coding_gene "0005515=protein binding, 0046982=protein heterodimerization activity, 0019781=NEDD8 activating enzyme activity, 0004839=ubiquitin activating enzyme activity" 0045116=protein neddylation 0043234=protein complex "dAPPBP1, APPBP1, CG7828, anon-WO0140519.225, dAPP-BP1" "IPR030667=NEDD8-activating enzyme E1 regulatory subunit APP-BP1, IPR000594=THIF-type NAD/FAD binding fold, IPR016040=NAD(P)-binding domain" CG7828 16-Dec-15 2015_12 ENSDARG00000011301(nae1) YPR180W(AOS1) WBGene00006735(ula-1) ENSXETG00000011245(NAE1) ENSMUSG00000031878(Nae1) ENSG00000159593(NAE1) FBgn0025564 anon-23Cb anon-23Cb http://flybase.net/reports/FBgn0025564.html gene c1.5 16-Dec-15 2015_12 FBgn0051800 CG31800 http://flybase.net/reports/FBgn0051800.html protein_coding_gene IPR019534=Protein of unknown function DUF2452 CG31800 16-Dec-15 2015_12 "ENSDARG00000071211(zgc:112255),ENSDARG00000070194,ENSDARG00000070185" WBGene00007436(C08B11.9) ENSXETG00000012074() ENSMUSG00000078584(AU022252) ENSG00000164008(LOC100129924) viable FBgn0065192 l(2)SH2328 lethal (2) SH2328 http://flybase.net/reports/FBgn0065192.html gene l(2)SH2 2328 16-Dec-15 2015_12 "lethal,recessive" FBgn0042086 Tsp42Eb Tetraspanin 42Eb http://flybase.net/reports/FBgn0042086.html FBgn0042139 protein_coding_gene 0016021=integral component of membrane "Tetrasp42Eb, CG18816, Dm.Tsp42Eb, tetraspanin 42E, LP06288, BEST:LP06288" "IPR000301=Tetraspanin, IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG18816 16-Dec-15 2015_12 FBgn0026761 Trap1 Trap1 http://flybase.net/reports/FBgn0026761.html protein_coding_gene "0005524=ATP binding, 0051082=unfolded protein binding, 0016887=ATPase activity" "0006457=protein folding, 0006979=response to oxidative stress, 1902884=positive regulation of response to oxidative stress, 0009408=response to heat, 0034514=mitochondrial unfolded protein response" "0005739=mitochondrion, 0005811=lipid particle" "TRAP1, TRAP1dr, CG3152, dtrap-1, trap1, Hsp90-related protein, TNF receptor-associated protein 1" "IPR001404=Heat shock protein Hsp90 family, IPR020575=Heat shock protein Hsp90, N-terminal, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR003594=Histidine kinase-like ATPase, C-terminal domain" CG3152 16-Dec-15 2015_12 "ENSDARG00000063038,ENSDARG00000024317(trap1)" WBGene00020110(R151.7) ENSMUSG00000005981(Trap1) ENSG00000126602(TRAP1) "viable,short lived,heat stress response defective,oxidative stress response defective,chemical sensitive,locomotor behavior defective,progressive,chemical resistant,fertile" FBgn0083248 EB2 EB2 http://flybase.net/reports/FBgn0083248.html gene 16-Dec-15 2015_12 FBgn0000737 fs(1)A97 female sterile (1) A97 http://flybase.net/reports/FBgn0000737.html gene fs(1)97 16-Dec-15 2015_12 chemical sensitive FBgn0261599 RpS29 Ribosomal protein S29 http://flybase.net/reports/FBgn0261599.html "FBgn0037752, FBgn0025195, FBgn0061386, FBgn0062070, FBgn0064844, FBgn0064994, FBgn0065013, FBgn0002620" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0048666=neuron development, 0022008=neurogenesis" 0022627=cytosolic small ribosomal subunit "unnamed, BcDNA:AT28563, Minute (3) 85E, CG8495, anon-EST:fe3B4, M(3)85E, anon-fast-evolving-3B4, BcDNA:AT13329, anon-WO0118547.360, chr3R:5604479..5604622, BcDNA:RH06643, M(3)LS5" "IPR018271=Ribosomal protein S14, conserved site, IPR001209=Ribosomal protein S14" CG8495 16-Dec-15 2015_12 ENSDARG00000041232(rps29) "YLR388W(RPS29A),YDL061C(RPS29B)" WBGene00004498(rps-29) ENSXETG00000027734(rps29) "ENSMUSG00000063180(Gm10126),ENSMUSG00000034892(Rps29),ENSMUSG00000059064(Gm10059)" ENSG00000213741(RPS29) DRSC16433 IEK -1.90097173 -0.687411618 -1.003828682 -3.844410139 0.307976209 2.328242392 FBgn0050015 CG30015 http://flybase.net/reports/FBgn0050015.html "FBgn0027733, FBgn0033559, FBgn0033560" protein_coding_gene "CG7701, anon-EST:Posey2, CG7699" CG30015 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC07027 K 0.474843328 0.367340697 0.465262046 0.429242465 0.48105363 1.829455721 FBgn0040153 l(1)G0469 lethal (1) G0469 http://flybase.net/reports/FBgn0040153.html "FBgn0030547, FBgn0030548, FBgn0052597, FBgn0066821" protein_coding_gene "CG11595, CG12482, anon-WO03040301.232, CG32597" CG32597 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,viable" DRSC19412 E 0.42937985 0.579799864 1.902219807 0.390430675 -0.383355396 -0.39756549 FBgn0262821 CG43192 http://flybase.net/reports/FBgn0262821.html protein_coding_gene "noncoding_6564, noncoding_6907" CG43192 16-Dec-15 2015_12 FBgn0029737 CG6903 http://flybase.net/reports/FBgn0029737.html protein_coding_gene "0016746=transferase activity, transferring acyl groups" 0007041=lysosomal transport 0005765=lysosomal membrane CG6903 16-Dec-15 2015_12 ENSXETG00000004461(HGSNAT) ENSMUSG00000037260(Hgsnat) ENSG00000165102(HGSNAT) "viable,fertile" FBgn0020861 corallium corallium http://flybase.net/reports/FBgn0020861.html gene cor 16-Dec-15 2015_12 eye color defective pigment cell FBgn0027600 obst-B obstructor-B http://flybase.net/reports/FBgn0027600.html FBgn0028958 protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region "CG4778, CK00178, BcDNA:GH02976, Obstructor-B, BEST:CK00178" IPR002557=Chitin binding domain CG4778 16-Dec-15 2015_12 viable FBgn0028181 l(3)S024506 lethal (3) S024506 http://flybase.net/reports/FBgn0028181.html gene 0245/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0260000 CG17570 http://flybase.net/reports/FBgn0260000.html "FBgn0032948, FBgn0046671" protein_coding_gene "38C.24, anon-38C.24" CG17570 16-Dec-15 2015_12 FBgn0035693 CG8219 http://flybase.net/reports/FBgn0035693.html protein_coding_gene "0008320=protein transmembrane transporter activity, 0008536=Ran GTPase binding" 0006606=protein import into nucleus 0005643=nuclear pore "EP(3)3072, 148274_at" "IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical" CG8219 16-Dec-15 2015_12 YBR017C(KAP104) WBGene00002076(imb-2) "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030554 CG1434 http://flybase.net/reports/FBgn0030554.html protein_coding_gene "0017150=tRNA dihydrouridine synthase activity, 0050660=flavin adenine dinucleotide binding" "0055114=oxidation-reduction process, 0008033=tRNA processing" "IPR018517=tRNA-dihydrouridine synthase, conserved site, IPR001269=tRNA-dihydrouridine synthase, IPR013785=Aldolase-type TIM barrel, IPR014720=Double-stranded RNA-binding domain" CG1434 16-Dec-15 2015_12 YNR015W(SMM1) WBGene00013201(Y54E5A.6) ENSXETG00000005436(TEgg009k10.1) ENSMUSG00000031901(Dus2l) ENSG00000167264(DUS2L) viable FBgn0060533 l(3)S100806 lethal (3) S100806 http://flybase.net/reports/FBgn0060533.html gene 1008/06 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037794 CG6254 http://flybase.net/reports/FBgn0037794.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG6254 16-Dec-15 2015_12 WBGene00009448(zfp-2) viable FBgn0043530 Obp51a Odorant-binding protein 51a http://flybase.net/reports/FBgn0043530.html "FBgn0050473, FBgn0063478" protein_coding_gene 0005549=odorant binding "0007606=sensory perception of chemical stimulus, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "Obp-c, DmelObp51a, unnamed, 51a, CG30473, anon-AE003812.1" IPR006170=Pheromone/general odorant binding protein CG30473 16-Dec-15 2015_12 viable FBgn0010244 Mst77F-ë¬Y2 Mst77F pseudogene on Y 2 http://flybase.net/reports/FBgn0010244.html pseudogene_attribute "Mst77-Psi2, 18c" 16-Dec-15 2015_12 FBgn0261383 IntS6 Integrator 6 http://flybase.net/reports/FBgn0261383.html "FBgn0027321, FBgn0029797" protein_coding_gene "0034472=snRNA 3'-end processing, 0016180=snRNA processing" 0032039=integrator complex "l(1)G0060, CG3125, Int6" "IPR029307=INTS6/SAGE1/DDX26B/CT45, C-terminal, IPR002035=von Willebrand factor, type A" CG3125 16-Dec-15 2015_12 "lethal,recessive,viable,fertile" DRSC18281 I 0.637531439 -2.118115405 1.285873248 -1.289482666 0.465003313 0.336119248 FBgn0004137 l(2)43Ef lethal (2) 43Ef http://flybase.net/reports/FBgn0004137.html gene 16-Dec-15 2015_12 lethal FBgn0003218 rdgB retinal degeneration B http://flybase.net/reports/FBgn0003218.html protein_coding_gene "0005388=calcium-transporting ATPase activity, 0035091=phosphatidylinositol binding, 0008525=phosphatidylcholine transporter activity, 0005509=calcium ion binding, 0046872=metal ion binding, 0008526=phosphatidylinositol transporter activity" "0045494=photoreceptor cell maintenance, 0007608=sensory perception of smell, 0071482=cellular response to light stimulus, 0016056=rhodopsin mediated signaling pathway, 0007603=phototransduction, visible light, 0007601=visual perception, 0046488=phosphatidylinositol metabolic process, 0007602=phototransduction, 0006810=transport, 0016059=deactivation of rhodopsin mediated signaling" "0005886=plasma membrane, 0016029=subrhabdomeral cisterna, 0005622=intracellular, 0016021=integral component of membrane, 0005887=integral component of plasma membrane" "hypoF, ota1, RdgBalpha, x36, receptor-degeneration-II, DrdgB, receptor degeneration B, RdgB, CG11111, DrdgBalpha" "IPR031315=LNS2/PITP, IPR001666=Phosphatidylinositol transfer protein, IPR023393=START-like domain, IPR023214=HAD-like domain, IPR004177=DDHD domain" CG11111 16-Dec-15 2015_12 ENSDARG00000055255 WBGene00010813(M01F1.7) ENSXETG00000020679(PITPNM3) "ENSMUSG00000024851(Pitpnm1),ENSMUSG00000029406(Pitpnm2)" "ENSG00000090975(PITPNM2),ENSG00000110697(PITPNM1)" adult stage adult head

"smell perception defective,recessive,behavior defective,neuroanatomy defective,visual behavior defective,neurophysiology defective,viable,dominant" "eye photoreceptor cell,ommatidium,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,glial cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell,rhabdomere,cell autonomous,somatic clone,lamina,maxillary palpus,photoreceptor cell R7,photoreceptor cell R8,ocellus rhabdomere,ocellus retinula cell,rhabdomere R7" FBgn0040892 CG14634 http://flybase.net/reports/FBgn0040892.html protein_coding_gene CG14634 16-Dec-15 2015_12 "viable,fertile" FBgn0267096 CR45536 http://flybase.net/reports/FBgn0267096.html non_protein_coding_gene CR45536 16-Dec-15 2015_12 FBgn0053914 CG33914 http://flybase.net/reports/FBgn0053914.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG33914 16-Dec-15 2015_12 FBgn0024274 Vitamin-D-hydroxylase Vitamin D hydroxylase http://flybase.net/reports/FBgn0024274.html gene 0004498=calcidiol 1-monooxygenase activity 16-Dec-15 2015_12 FBgn0052645 CG32645 http://flybase.net/reports/FBgn0052645.html "FBgn0030453, FBgn0030454" protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "CG4331, CG15716" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG32645 16-Dec-15 2015_12 WBGene00003813(nrf-6) ENSMUSG00000046610(5330437I02Rik) "viable,fertile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267996 CR46263 http://flybase.net/reports/FBgn0267996.html non_protein_coding_gene CR46263 16-Dec-15 2015_12 FBgn0037217 CG14636 http://flybase.net/reports/FBgn0037217.html FBan0014636 protein_coding_gene 0007605=sensory perception of sound CG14636 16-Dec-15 2015_12 "auditory perception defective,viable,fertile" FBgn0029552 CG14631 http://flybase.net/reports/FBgn0029552.html protein_coding_gene CG14631 16-Dec-15 2015_12 viable FBgn0011088 l(1)Q48 lethal (1) Q48 http://flybase.net/reports/FBgn0011088.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0035982 CG4461 http://flybase.net/reports/FBgn0035982.html FBgn0043822 protein_coding_gene 0009408=response to heat "4461, Hsp20, DmCG4461, BEST:GH12586, gh12586, 148460_at" "IPR008978=HSP20-like chaperone, IPR031107=Small heat shock protein HSP20, IPR002068=Alpha crystallin/Hsp20 domain" CG4461 16-Dec-15 2015_12 WBGene00002021(hsp-17) viable DRSC10423 K 0.694015053 0.382321768 0.284991205 0.242377893 -0.19085145 1.532109202 FBgn0259837 Su(Ste):CR42406 Su(Ste):CR42406 http://flybase.net/reports/FBgn0259837.html non_protein_coding_gene "CR42406, RR42186" CR42406 16-Dec-15 2015_12 FBgn0037730 CG9444 http://flybase.net/reports/FBgn0037730.html protein_coding_gene 0005427=proton-dependent oligopeptide secondary active transmembrane transporter activity 0006857=oligopeptide transport 0016020=membrane "IPR000109=Proton-dependent oligopeptide transporter family, IPR018456=PTR2 family proton/oligopeptide symporter, conserved site, IPR020846=Major facilitator superfamily domain" CG9444 16-Dec-15 2015_12 YKR093W(PTR2) "viable,fertile" FBgn0023224 E(Egfr)B56 Enhancer of Egfr B56 http://flybase.net/reports/FBgn0023224.html gene 16-Dec-15 2015_12 "wing vein L2,wing vein L4,wing vein L5" FBgn0020787 re-o red-orange http://flybase.net/reports/FBgn0020787.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0265942 CR44729 http://flybase.net/reports/FBgn0265942.html non_protein_coding_gene CR44729 16-Dec-15 2015_12 FBgn0030114 CG17754 http://flybase.net/reports/FBgn0030114.html FBgn0047189 protein_coding_gene 0006909=phagocytosis BcDNA:LP02641 "IPR000210=BTB/POZ domain, IPR015916=Galactose oxidase, beta-propeller, IPR017096=BTB-kelch protein, IPR011705=BTB/Kelch-associated, IPR006652=Kelch repeat type 1, IPR030606=Kelch-like protein 5, IPR011333=POZ domain" CG17754 16-Dec-15 2015_12 ENSDARG00000062122(klhl5) "ENSXETG00000018507(KLHL5),ENSXETG00000015861(KLHL4)" "ENSMUSG00000054920(Klhl5),ENSMUSG00000022076(Klhl1),ENSMUSG00000025597(Klhl4)" "ENSG00000109790(KLHL5),ENSG00000150361(KLHL1),ENSG00000102271(KLHL4)" "viable,fertile" FBgn0004692 Sgs9 Salivary gland secretion 9 http://flybase.net/reports/FBgn0004692.html gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "GP5, P5, Sgs" 16-Dec-15 2015_12 FBgn0262566 CG43106 http://flybase.net/reports/FBgn0262566.html protein_coding_gene CG43106 16-Dec-15 2015_12 FBgn0000483 dotted dotted http://flybase.net/reports/FBgn0000483.html gene dot 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,maternal effect,recessive,some die during larval stage" FBgn0086778 nAChRë±7 nicotinic Acetylcholine Receptor ë±7 http://flybase.net/reports/FBgn0086778.html "FBgn0005396, FBgn0001102, FBgn0001290, FBgn0031013, FBgn0052538, FBgn0031014" protein_coding_gene 0004889=acetylcholine-activated cation-selective channel activity "0007632=visual behavior, 0060079=regulation of excitatory postsynaptic membrane potential, 0007630=jump response, 0007268=synaptic transmission, 0007271=synaptic transmission, cholinergic, 0006812=cation transport" "0014069=postsynaptic density, 0045211=postsynaptic membrane, 0005892=acetylcholine-gated channel complex, 0030425=dendrite, 0043197=dendritic spine" "non-jumper-507, jpl, giant fibre A, Dalpha7 subunit of the acetylcholine receptor, gfA, nj522, nAChR, nj520, nicotinic Acetylcholine Receptor alpha 18C, non-jumper-75, nAChR-Dalpha7, Shaker cognate L, Da7, non-jumper-522, gfa, CG8082, nAcRalpha-18C, nAcRalpha-7, giant fiber A, jumpless, non-jumper-520, Dalpha7, CT24218, CG8109, nj75, CG32538, Dalpha7-nAChR, Dalpha7 nAChR, nj507, nj54, Dalpha7 subunit of the nicotinic acetylcholine receptor, non-jumper-54" "IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006201=Neurotransmitter-gated ion-channel, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR002394=Nicotinic acetylcholine receptor" CG32538 16-Dec-15 2015_12 "ENSDARG00000037427(si:ch211-39a7.1),ENSDARG00000035785(chrna7),ENSDARG00000037424,ENSDARG00000033954" WBGene00000055(acr-16) "ENSXETG00000016395(),ENSXETG00000018003()" ENSMUSG00000030525(Chrna7) "ENSG00000175344(CHRNA7),ENSG00000166664(CHRFAM7A)" FBgn0069195 l(2)c00221 lethal (2) c00221 http://flybase.net/reports/FBgn0069195.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0033995 GPHR Golgi pH Regulator http://flybase.net/reports/FBgn0033995.html protein_coding_gene "0007030=Golgi organization, 0032940=secretion by cell" "0005783=endoplasmic reticulum, 0016020=membrane" "dGPHR, CG8090" "IPR022535=Golgi pH regulator, conserved domain, IPR015672=The Golgi pH regulator/GPCR-type G protein, IPR025969=Abscisic acid G-protein coupled receptor-like domain" CG8090 16-Dec-15 2015_12 YHR078W() "WBGene00007528(C11H1.2),WBGene00013551(Y75B8A.16)" ENSXETG00000016309() ENSMUSG00000028096(Gpr89) "ENSG00000117262(GPR89A),ENSG00000188092(GPR89B),ENSG00000196644(GPR89C)" "lethal - all die before end of larval stage,small body,decreased cell size,decreased cell number,viable" "wing blade,endoplasmic reticulum,cis-Golgi network" FBgn0037963 Cad87A Cadherin 87A http://flybase.net/reports/FBgn0037963.html protein_coding_gene 0005509=calcium ion binding "0044331=cell-cell adhesion mediated by cadherin, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" "0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "Cad87A, CG6977, Cad87, CT21611, DCad87A" "IPR002126=Cadherin, IPR015919=Cadherin-like, IPR020894=Cadherin conserved site" CG6977 16-Dec-15 2015_12 "viable,fertile" FBgn0030788 Sap30 SIN3-associated polypeptide 30 http://flybase.net/reports/FBgn0030788.html protein_coding_gene 0003714=transcription corepressor activity 0000118=histone deacetylase complex "SAP30, CG4756, cg4756" "IPR025717=Histone deacetylase complex subunit SAP30 zinc-finger, IPR024145=Histone deacetylase complex subunit SAP30/SAP30-like, IPR025718=Histone deacetylase complex subunit SAP30, Sin3 binding domain" CG4756 16-Dec-15 2015_12 ENSDARG00000030213(sap30l) "ENSXETG00000008480(TEgg038l14.1),ENSXETG00000016915(sap30)" "ENSMUSG00000020519(Sap30l),ENSMUSG00000031609(Sap30)" "ENSG00000164576(SAP30L),ENSG00000164105(SAP30)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0259970 Sfp70A4 Seminal fluid protein 70A4 http://flybase.net/reports/FBgn0259970.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG42480, Seminal fluid protein 70A4" CG42480 16-Dec-15 2015_12 FBgn0025340 anon-58Fc anon-58Fc http://flybase.net/reports/FBgn0025340.html gene 2-Nov 16-Dec-15 2015_12 FBgn0032246 CG5168 http://flybase.net/reports/FBgn0032246.html protein_coding_gene 0046872=metal ion binding "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019775=WD40 repeat, conserved site, IPR017455=Zinc finger, FYVE-related, IPR011011=Zinc finger, FYVE/PHD-type, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR000306=FYVE zinc finger, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat" CG5168 16-Dec-15 2015_12 ENSDARG00000040453(wdfy2) WBGene00008402(wdfy-2) ENSXETG00000020718(WDFY2) "ENSMUSG00000014547(Wdfy2),ENSMUSG00000073643(Wdfy1)" "ENSG00000139668(WDFY2),ENSG00000085449(WDFY1)" viable heart primordium DRSC29755 K -0.493664356 -0.052151597 0.220216004 -0.164776876 0.236567151 1.689598136 FBgn0043350 EP3474 EP3474 http://flybase.net/reports/FBgn0043350.html gene unnamed 16-Dec-15 2015_12 visible "scutellar bristle,ectopic,dorsocentral bristle,tormogen cell" FBgn0032066 LManIII Lysosomal ë±-mannosidase III http://flybase.net/reports/FBgn0032066.html protein_coding_gene "0004559=alpha-mannosidase activity, 0008270=zinc ion binding, 0030246=carbohydrate binding" 0006013=mannose metabolic process 0005764=lysosome "LManIII, CG9463" "IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR015341=Glycoside hydrolase, family 38, central domain, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR011013=Galactose mutarotase-like domain, IPR000602=Glycoside hydrolase family 38, N-terminal domain, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel" CG9463 16-Dec-15 2015_12 WBGene00018877(aman-1) ENSXETG00000011609(MAN2B2) viable FBgn0086395 BG02209 http://flybase.net/reports/FBgn0086395.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0261561 CG42675 http://flybase.net/reports/FBgn0261561.html "FBgn0051554, FBgn0037381, FBgn0044622" protein_coding_gene "anon-WO0140519.247, CG10999, CG31554" IPR026319=Zinc finger C2HC domain-containing protein CG42675 16-Dec-15 2015_12 ENSXETG00000013249(FAM164C) ENSMUSG00000045064(Fam164c) DRSC12157 E -0.314297088 -0.300112246 -1.618046608 0.34588869 -0.20862948 -0.314250778 FBgn0025571 SF1 Splicing factor 1 http://flybase.net/reports/FBgn0025571.html FBgn0038518 protein_coding_gene "0044822=poly(A) RNA binding, 0008270=zinc ion binding, 0045131=pre-mRNA branch point binding" "0000398=mRNA splicing, via spliceosome, 0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior, 0022008=neurogenesis" "0071011=precatalytic spliceosome, 0005681=spliceosomal complex, 0005634=nucleus" "dSF1, CG5836, cg5836, p70, splicing factor 1" "IPR004087=K Homology domain, IPR031150=BBP/SF1 family, IPR001878=Zinc finger, CCHC-type, IPR004088=K Homology domain, type 1" CG5836 16-Dec-15 2015_12 ENSDARG00000008188(sf1) YLR116W(MSL5) WBGene00013808(sfa-1) ENSXETG00000008434(sf1) ENSMUSG00000024949(Sf1) ENSG00000168066(SF1) "behavior defective,recessive,viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0029949 CG15035 http://flybase.net/reports/FBgn0029949.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0004721=phosphoprotein phosphatase activity" 0006470=protein dephosphorylation 0005739=mitochondrion IPR001932=PPM-type phosphatase domain CG15035 16-Dec-15 2015_12 "ENSDARG00000052658(si:ch211-193e13.3),ENSDARG00000011122(pptc7)" YHR076W(PTC7) WBGene00012362(W09D10.4) ENSXETG00000020935(PPTC7) ENSMUSG00000038582(Pptc7) ENSG00000196850(PPTC7) viable FBgn0040072 snRNP-U1-70K::Hsap\SRSF1 SFRS1 http://flybase.net/reports/FBgn0040072.html engineered_fusion_gene "snRNP-U1-70K::Hsap\SFRS1, snRNP70K::Hsap\SFRS1, U1-70K" 16-Dec-15 2015_12 FBgn0060384 l(3)S134415b lethal (3) S134415b http://flybase.net/reports/FBgn0060384.html gene 1344/15 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033579 CG13229 http://flybase.net/reports/FBgn0033579.html "FBgn0046591, FBgn0046592" protein_coding_gene "0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "Dm CG13229, anon-WO0170980.142, anon-WO0170980.143" "IPR019427=7TM GPCR, serpentine receptor class w (Srw), IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG13229 16-Dec-15 2015_12 "ENSDARG00000063156,ENSDARG00000015601" "WBGene00010191(F57B7.1),WBGene00007951(C35A5.7)" "ENSG00000180269(GPR139),ENSG00000221981" FBgn0038526 CG14327 http://flybase.net/reports/FBgn0038526.html FBgn0064897 protein_coding_gene BcDNA:RE25364 CG14327 16-Dec-15 2015_12 viable DRSC14806 K -0.313426307 0.501895224 -0.231652026 -0.13648468 -1.589706757 -0.985903154 FBgn0011168 l(1)DM-5 lethal (1) DM-5 http://flybase.net/reports/FBgn0011168.html FBgn0010204 gene 16-Dec-15 2015_12 lethal FBgn0016006 l(3)63Ee lethal (3) 63Ee http://flybase.net/reports/FBgn0016006.html gene l(3)SH1 16-Dec-15 2015_12 "lethal,recessive" FBgn0039640 CG14516 http://flybase.net/reports/FBgn0039640.html protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571=ERAP1-like C-terminal domain" CG14516 16-Dec-15 2015_12 "ENSDARG00000036809(LOC555478),ENSDARG00000019751,ENSDARG00000060732,ENSDARG00000041083(si:ch211-200o3.4)" WBGene00009865(F49B2.6) ENSMUSG00000039062(Anpep) ENSG00000166825(ANPEP) viable FBgn0038357 CG5623 http://flybase.net/reports/FBgn0038357.html FBgn0063744 protein_coding_gene BcDNA:AT10995 IPR009961=Protein of unknown function DUF1487 CG5623 16-Dec-15 2015_12 viable FBgn0051660 pog poor gastrulation http://flybase.net/reports/FBgn0051660.html "FBgn0031641, FBgn0031642, FBgn0046563, FBgn0046564" protein_coding_gene 0004930=G-protein coupled receptor activity "0002805=regulation of antimicrobial peptide biosynthetic process, 0007186=G-protein coupled receptor signaling pathway, 0007377=germ-band extension" 0005887=integral component of plasma membrane "anon-WO0170980.181, CG11923, CG31660, CG11925, anon-WO0170980.182, pg" "IPR017978=GPCR, family 3, C-terminal" CG31660 16-Dec-15 2015_12 viable embryo FBgn0011270 Pglym87 Pglym87 http://flybase.net/reports/FBgn0011270.html FBgn0038004 protein_coding_gene 0004619=phosphoglycerate mutase activity 0006096=glycolytic process "pglym87, Pglym, CG17645" "IPR029033=Histidine phosphatase superfamily, IPR001345=Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR005952=Phosphoglycerate mutase 1, IPR013078=Histidine phosphatase superfamily, clade-1" CG17645 16-Dec-15 2015_12 "ENSDARG00000014068(pgam1b),ENSDARG00000005423(pgam1a),ENSDARG00000057571(pgam2)" YKL152C(GPM1) "ENSXETG00000003433(),ENSXETG00000018980(pgam2)" "ENSMUSG00000011752(Pgam1),ENSMUSG00000020475(Pgam2)" "ENSG00000220515,ENSG00000171314(PGAM1),ENSG00000186076,ENSG00000164708(PGAM2)" viable FBgn0002091 l(2)57Ba lethal (2) 57Ba http://flybase.net/reports/FBgn0002091.html gene 16-Dec-15 2015_12 lethal FBgn0004201 l(3)84Dc lethal (3) 84Dc http://flybase.net/reports/FBgn0004201.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266241 CR44936 http://flybase.net/reports/FBgn0266241.html non_protein_coding_gene lincRNA.722 CR44936 16-Dec-15 2015_12 FBgn0011059 l(1)Q12 lethal (1) Q12 http://flybase.net/reports/FBgn0011059.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0001636 l(1)dn16 lethal (1) discs normal 16 http://flybase.net/reports/FBgn0001636.html gene l(1)d.norm.-16 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051292 CR31292 http://flybase.net/reports/FBgn0051292.html pseudogene_attribute CG31292 CR31292 16-Dec-15 2015_12 DRSC13120 E -0.505822752 0.114989139 3.121391905 0.220332354 -0.309384024 0.384903647 FBgn0036857 CG9629 http://flybase.net/reports/FBgn0036857.html protein_coding_gene 0004029=aldehyde dehydrogenase (NAD) activity 0055114=oxidation-reduction process "IPR016163=Aldehyde dehydrogenase, C-terminal, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR029510=Aldehyde dehydrogenase, glutamic acid active site, IPR016161=Aldehyde/histidinol dehydrogenase, IPR015590=Aldehyde dehydrogenase domain" CG9629 16-Dec-15 2015_12 ENSDARG00000018426(aldh7a1) WBGene00000115(alh-9) ENSMUSG00000053644(Aldh7a1) ENSG00000164904(ALDH7A1) viable FBgn0266056 Su(var)211 http://flybase.net/reports/FBgn0266056.html gene 211 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0034667 comr cookie monster http://flybase.net/reports/FBgn0034667.html FBgn0026154 protein_coding_gene "0005515=protein binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007283=spermatogenesis" "0035327=transcriptionally active chromatin, 0005634=nucleus, 0000785=chromatin" "zab, zuker-aly-like b, CG13493, Comr, Z2-1340" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000232=Heat shock factor (HSF)-type, DNA-binding" CG13493 16-Dec-15 2015_12 viable "testis,meiotic cell cycle,spermatid" FBgn0016038 mod(r) modifier of rudimentary http://flybase.net/reports/FBgn0016038.html "FBgn0025636, FBgn0045872" protein_coding_gene 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 0000813=ESCRT I complex "vps37A, CG17828, Vps37, EG:115C2.5, anon-WO0153538.78" "IPR009851=Modifier of rudimentary, Modr" CG17828 16-Dec-15 2015_12 " adult stage | male , adult stage | female " viable wing DRSC18794 I 1.972783565 1.350211448 -0.485607733 -0.112675819 0.026519377 -0.376289769 FBgn0052741 CG32741 http://flybase.net/reports/FBgn0052741.html protein_coding_gene 16-Dec-15 2015_12 FBgn0261504 7SLRNA:CR42652 Signal recognition particle 7SL RNA CR42652 http://flybase.net/reports/FBgn0261504.html non_protein_coding_gene "CR42652, 7SLRNA, 7SL RNA" CR42652 16-Dec-15 2015_12 FBgn0029971 ND-MNLL NADH dehydrogenase (ubiquinone) MNLL subunit http://flybase.net/reports/FBgn0029971.html FBgn0040924 protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NINM, NADH-ubiquinone oxidoreductase MNLL subunit, CG15328, CG18624, NADH ubiquinone oxidoreductase MNLL, NADH:ubiquinone oxidoreductase MNLL subunit, Dromel_CG18624_FBtr0071140_mORF" "IPR012575=NADH:ubiquinone oxidoreductase, MNLL subunit" CG18624 16-Dec-15 2015_12 "viable,visible,lethal,partially lethal - majority die,some die during pupal stage,heat sensitive" "trichogen cell,mesothoracic tergum" FBgn0060699 l(3)S071814b lethal (3) S071814b http://flybase.net/reports/FBgn0060699.html gene 0718/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0069137 mcl(3)Z5860 mcl(3)Z5860 http://flybase.net/reports/FBgn0069137.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0004803 fs(2)ltoWi42 female sterile (2) ltoWi42 http://flybase.net/reports/FBgn0004803.html gene "0046843=dorsal appendage formation, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile FBgn0005181 l(2)S3a lethal of Seto 3a http://flybase.net/reports/FBgn0005181.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036286 CG10616 http://flybase.net/reports/FBgn0036286.html protein_coding_gene 0012505=endomembrane system IPR029454=ODR-4-like CG10616 16-Dec-15 2015_12 ENSMUSG00000006010(BC003331) ENSG00000157181(C1orf27) "viable,body color defective" mesothoracic tergum FBgn0051099 CG31099 http://flybase.net/reports/FBgn0051099.html FBgn0039322 protein_coding_gene CG10551 "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG31099 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" "partially lethal - majority die,some die during pupal stage" FBgn0267905 CG46193 http://flybase.net/reports/FBgn0267905.html protein_coding_gene Mst35Ba-related CG46193 16-Dec-15 2015_12 FBgn0036165 chrb charybde http://flybase.net/reports/FBgn0036165.html "FBgn0025947, FBgn0046799, FBtr0076093" protein_coding_gene "0008258=head involution, 0045926=negative regulation of growth, 0009968=negative regulation of signal transduction, 0008219=cell death" 0005737=cytoplasm "anon-EST:Liang-2.51, EP(3)1035, char, BcDNA:GH09771, CG7533, clone 2.51, charybdis, Charybdis" IPR012918=RTP801-like CG7533 16-Dec-15 2015_12 ENSDARG00000037618(zgc:64114) "ENSMUSG00000046818(Ddit4l),ENSMUSG00000020108(Ddit4)" "ENSG00000168209(DDIT4),ENSG00000145358(DDIT4L)" "viable,fertile,long lived,stress response defective,recessive,decreased cell size,somatic clone" DRSC11335 I -1.754643025 0.638436099 -0.162952858 0.493145625 0.430228617 -0.080297201 FBgn0082163 splo splotchy http://flybase.net/reports/FBgn0082163.html gene 16-Dec-15 2015_12 "hemocyte,supernumerary,lamellocyte" FBgn0016818 l(1)L4 lethal (1) L4 http://flybase.net/reports/FBgn0016818.html gene L4 16-Dec-15 2015_12 "lethal,recessive" FBgn0069164 mcl(3)Z1550 mcl(3)Z1550 http://flybase.net/reports/FBgn0069164.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0029945 CG18155 http://flybase.net/reports/FBgn0029945.html protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity 0008152=metabolic process FBgn0029945 "IPR000873=AMP-dependent synthetase/ligase, IPR025110=AMP-binding enzyme C-terminal domain" CG18155 16-Dec-15 2015_12 ENSDARG00000059503(LOC562292) ENSXETG00000011261(ACSF3) ENSMUSG00000015016(Acsf3) ENSG00000176715(ACSF3) partially lethal - majority die FBgn0266329 CR44994 http://flybase.net/reports/FBgn0266329.html non_protein_coding_gene CR44994 16-Dec-15 2015_12 FBgn0027143 l(3)71DEd lethal (3) 71DEd http://flybase.net/reports/FBgn0027143.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0001890 l(2)21Dd lethal (2) 21Dd http://flybase.net/reports/FBgn0001890.html gene "l(2)neh4, l(2)neh-4" 16-Dec-15 2015_12 lethal FBgn0010345 Mst75Ca Male-specific RNA 75Ca http://flybase.net/reports/FBgn0010345.html FBgn0002861 gene "Mst75C, mst-2, mst(3)ag-2, mst(3)ag-15A" 16-Dec-15 2015_12 FBgn0014084 anon-20ABa anon-20ABa http://flybase.net/reports/FBgn0014084.html gene 16-Dec-15 2015_12 FBgn0025925 l(3)76BDd lethal (3) 76BDd http://flybase.net/reports/FBgn0025925.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260261 GSd239 http://flybase.net/reports/FBgn0260261.html gene 16-Dec-15 2015_12 lethal FBgn0082912 ë±-Spec::Actn ë±-Spec::Actn http://flybase.net/reports/FBgn0082912.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0025556 anon-88Bb anon-88Bb http://flybase.net/reports/FBgn0025556.html gene c5.5 16-Dec-15 2015_12 FBgn0265865 CR44654 http://flybase.net/reports/FBgn0265865.html non_protein_coding_gene lincRNA.988 CR44654 16-Dec-15 2015_12 FBgn0015409 l(1)12Ca lethal (1) 12Ca http://flybase.net/reports/FBgn0015409.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264486 CG43894 http://flybase.net/reports/FBgn0264486.html "FBgn0036322, FBgn0054032, FBgn0082654" protein_coding_gene "unnamed, BP1086, CG34032, HDC09916, CG14119" CG43894 16-Dec-15 2015_12 DRSC10123 IEK -0.241478584 -4.03319601 -0.647967371 -3.097112215 -2.235849481 -2.89281772 FBgn0002653 mat(2)cell-B maternal effect cellularisation defect B http://flybase.net/reports/FBgn0002653.html gene 0007349=cellularization mat(2)cellPH65 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0028379 fan farinelli http://flybase.net/reports/FBgn0028379.html FBgn0035836 protein_coding_gene 0007291=sperm individualization "0005886=plasma membrane, 0005783=endoplasmic reticulum, 0005789=endoplasmic reticulum membrane" CG7919 "IPR008962=PapD-like, IPR016763=Vesicle-associated membrane-protein-associated protein, IPR000535=Major sperm protein (MSP) domain" CG7919 16-Dec-15 2015_12 "YBL091C-A(SCS22),YER120W(SCS2)" "viable,fertile,semi-sterile" cystic bulge FBgn0035071 CG15859 http://flybase.net/reports/FBgn0035071.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025642 CG32812 http://flybase.net/reports/FBgn0025642.html FBgn0052812 protein_coding_gene 0005509=calcium ion binding 0010923=negative regulation of phosphatase activity 0005886=plasma membrane "EG:114D9.1, CG11408" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG32812 16-Dec-15 2015_12 viable FBgn0005331 pil3 pilosus on chromosome 3 http://flybase.net/reports/FBgn0005331.html gene "pilosus on third chromosome, pil-3" 16-Dec-15 2015_12 "visible,semidominant" abdominal sternite 6 FBgn0266360 CR45008 http://flybase.net/reports/FBgn0266360.html non_protein_coding_gene CR45008 16-Dec-15 2015_12 FBgn0083238 EP2494 EP2494 http://flybase.net/reports/FBgn0083238.html gene 16-Dec-15 2015_12 FBgn0065140 l(3)SH106 lethal (3) SH106 http://flybase.net/reports/FBgn0065140.html gene l(2)SH3 106 16-Dec-15 2015_12 "lethal,recessive" FBgn0015452 l(1)9Fl lethal (1) 9Fl http://flybase.net/reports/FBgn0015452.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0267113 CR45553 http://flybase.net/reports/FBgn0267113.html non_protein_coding_gene CR45553 16-Dec-15 2015_12 FBgn0267354 X-141 http://flybase.net/reports/FBgn0267354.html nuclear_gene Gene_X_141 16-Dec-15 2015_12 FBgn0043884 mask multiple ankyrin repeats single KH domain http://flybase.net/reports/FBgn0043884.html "FBgn0039173, FBgn0039174, FBgn0040597, FBgn0051138" protein_coding_gene "0003723=RNA binding, 0005200=structural constituent of cytoskeleton" "0043066=negative regulation of apoptotic process, 0008283=cell proliferation, 0051298=centrosome duplication, 0007016=cytoskeletal anchoring at plasma membrane, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0019730=antimicrobial humoral response, 0001751=compound eye photoreceptor cell differentiation, 0046427=positive regulation of JAK-STAT cascade" "0005811=lipid particle, 0005737=cytoplasm, 0005829=cytosol" "EC3-6, MASK, Mask, cg6313, CG6313, CG18671, CG6268, CG31138, CG33106" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG33106 16-Dec-15 2015_12 WBGene00011240(R11A8.7) "ENSXETG00000018337(),ENSXETG00000008132(ANKRD17)" "ENSMUSG00000024483,ENSMUSG00000055204(Ankrd17)" "ENSG00000131503(ANKHD1-EIF4EBP3),ENSG00000132466(ANKRD17)" "viable,fertile,visible,small body,increased cell death,lethal - all die before end of larval stage,some die during larval stage,recessive,somatic clone,body color defective,partially lethal - majority die,some die during pupal stage" "eye,heart primordium,eye-antennal disc,ommatidial precursor cluster,embryonic/larval digestive system,photoreceptor cell,somatic clone,photoreceptor cell R7,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,dorsal appendage,trichogen cell,mesothoracic tergum" DRSC25063 K -0.259530412 0.354541624 -0.478333527 -0.63078145 0.237097569 2.26080927 FBgn0264570 CR43942 http://flybase.net/reports/FBgn0264570.html non_protein_coding_gene CR43942 16-Dec-15 2015_12 FBgn0010182 tu(2)D tu(2)D http://flybase.net/reports/FBgn0010182.html gene 16-Dec-15 2015_12 FBgn0038531 CG14325 http://flybase.net/reports/FBgn0038531.html protein_coding_gene CG14325 16-Dec-15 2015_12 "ENSDARG00000061564,ENSDARG00000010756(nod2),ENSDARG00000069264(zgc:136791),ENSDARG00000071108,ENSDARG00000068970,ENSDARG00000068964,ENSDARG00000067858,ENSDARG00000067702,ENSDARG00000070248" ENSXETG00000010891(TCTE1) ENSMUSG00000023949(Tcte1) ENSG00000146221(TCTE1) "viable,fertile" FBgn0069999 BG01613 BG01613 http://flybase.net/reports/FBgn0069999.html gene 16-Dec-15 2015_12 stress response defective FBgn0263515 mir-4983 mir-4983 stem loop http://flybase.net/reports/FBgn0263515.html miRNA_gene "CR43500, dme-mir-4983" CR43500 16-Dec-15 2015_12 FBgn0044501 Cyp450_U5csm Cyp450_U5csm http://flybase.net/reports/FBgn0044501.html gene "0030976=thiamine pyrophosphate binding, 0009055=electron carrier activity, 0000287=magnesium ion binding" DU5csm "IPR000399=TPP-binding enzyme, conserved site" 16-Dec-15 2015_12 FBgn0001457 l(1)7Dk lethal (1) 7Dk http://flybase.net/reports/FBgn0001457.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0058303 CG40303 http://flybase.net/reports/FBgn0058303.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002198 l(3)67Ab lethal (3) 67Ab http://flybase.net/reports/FBgn0002198.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0040138 l(1)G0493 lethal (1) G0493 http://flybase.net/reports/FBgn0040138.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002428 l(3)F34 lethal (3) F34 http://flybase.net/reports/FBgn0002428.html gene l(3)34 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0002296 l(3)80Fg lethal (3) 80Fg http://flybase.net/reports/FBgn0002296.html gene "80Fg, l4A, l(3)Lh4A, lethal 4A" 16-Dec-15 2015_12 "lethal,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037027 HIPP1 HP1 and insulator partner protein 1 http://flybase.net/reports/FBgn0037027.html protein_coding_gene "0005515=protein binding, 0043035=chromatin insulator sequence binding, 0003824=catalytic activity" 0008152=metabolic process "HP1 and insulator partner protein-1, CG3680" "IPR001753=Crotonase superfamily, IPR029045=ClpP/crotonase-like domain" CG3680 16-Dec-15 2015_12 "ENSMUSG00000059288(Cdyl),ENSMUSG00000031758(Cdyl2)" "ENSG00000153046(CDYL),ENSG00000129873(CDY2B),ENSG00000182415(CDY2A),ENSG00000172288(CDY1),ENSG00000172352(CDY1B),ENSG00000166446(CDYL2)" viable FBgn0267689 CG46025 http://flybase.net/reports/FBgn0267689.html "FBgn0031944, FBgn0031943" protein_coding_gene "CG7196, CG14538" CG46025 16-Dec-15 2015_12 FBgn0262426 mir-283 mir-283 stem loop http://flybase.net/reports/FBgn0262426.html "FBgn0067708, FBgn0262273" miRNA_gene 0045880=positive regulation of smoothened signaling pathway "Dme-miR-283, dme-mir-283, CR33599, miR283, 283, miR-283, CR42980, mir-283" CR42980 16-Dec-15 2015_12 viable FBgn0037229 CG9766 http://flybase.net/reports/FBgn0037229.html protein_coding_gene 0022008=neurogenesis "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR003961=Fibronectin type III" CG9766 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0004997 cr-a cream a http://flybase.net/reports/FBgn0004997.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0264958 CR44127 http://flybase.net/reports/FBgn0264958.html non_protein_coding_gene lincRNA.253 CR44127 16-Dec-15 2015_12 FBgn0051040 Cog7 Cog7 http://flybase.net/reports/FBgn0051040.html FBgn0039724 protein_coding_gene "0006886=intracellular protein transport, 0000916=actomyosin contractile ring contraction, 0007112=male meiosis cytokinesis, 0007030=Golgi organization" "0017119=Golgi transport complex, 0036063=acroblast, 0005794=Golgi apparatus" "CG31040, CG7880" IPR019335=Conserved oligomeric Golgi complex subunit 7 CG31040 16-Dec-15 2015_12 ENSDARG00000061372(cog7) ENSXETG00000012431(Q5FW35_XENTR) ENSMUSG00000034951(Cog7) ENSG00000168434(COG7) "viable,male sterile,cytokinesis defective,male" "spermatid,contractile ringBSC861),Golgi stack,spermatocyte,acroblast,spermatid axoneme,onion stage spermatid" FBgn0024669 l(2)k03901 lethal (2) k03901 http://flybase.net/reports/FBgn0024669.html gene 39/1 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0058131 CG40131 http://flybase.net/reports/FBgn0058131.html FBan0040131 protein_coding_gene 16-Dec-15 2015_12 FBgn0046838 l(3)A4-4L5 lethal (3) A4-4L5 http://flybase.net/reports/FBgn0046838.html gene 16-Dec-15 2015_12 lethal FBgn0010367 dsx-c35A doublesex cognate 35A http://flybase.net/reports/FBgn0010367.html gene dsx-c35 16-Dec-15 2015_12 FBgn0034996 CG13575 http://flybase.net/reports/FBgn0034996.html "FBgn0046587, FBgn0046588" protein_coding_gene "0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity, 0008528=G-protein coupled peptide receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.149, anon-WO0170980.148" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG13575 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" DRSC22851 K 0.46446077 0.800247558 0.826322345 0.759144202 0.67557251 3.932458349 FBgn0001295 k kidney http://flybase.net/reports/FBgn0001295.html gene 16-Dec-15 2015_12 "visible,dominant,viable" "arista,eye,antenna,vibrissae" FBgn0000215 broadened broadened http://flybase.net/reports/FBgn0000215.html gene brd 16-Dec-15 2015_12 "visible,recessive" wing FBgn0016044 ms(3)ods male sterile (3) only diploid stages http://flybase.net/reports/FBgn0016044.html gene 16-Dec-15 2015_12 FBgn0266843 CR45305 http://flybase.net/reports/FBgn0266843.html non_protein_coding_gene CR45305 16-Dec-15 2015_12 FBgn0030187 Ipod Interaction partner of Dnmt2 http://flybase.net/reports/FBgn0030187.html protein_coding_gene 0006306=DNA methylation "CG2961, IPOD" CG2961 16-Dec-15 2015_12 FBgn0083045 snoRNA:ë¬18S-1389b snoRNA:ë¬18S-1389b http://flybase.net/reports/FBgn0083045.html snoRNA_gene "psi18s-1389b, CR34557" CR34557 16-Dec-15 2015_12 FBgn0000260 cast ojos castanos http://flybase.net/reports/FBgn0000260.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0051441 CG31441 http://flybase.net/reports/FBgn0051441.html FBgn0037886 protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus CG5135 "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG31441 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC27463 K 1.489355368 -0.358978521 -0.180885701 -0.001648519 0.35700909 1.744619339 FBgn0069107 mus317 mutagen-sensitive 317 http://flybase.net/reports/FBgn0069107.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0026269 anon-X2 anon-X2 http://flybase.net/reports/FBgn0026269.html gene X2 16-Dec-15 2015_12 FBgn0038277 RpS5b Ribosomal protein S5b http://flybase.net/reports/FBgn0038277.html protein_coding_gene "0003723=RNA binding, 0003735=structural constituent of ribosome" "0006412=translation, 0022008=neurogenesis" "0022627=cytosolic small ribosomal subunit, 0005875=microtubule associated complex" "RS5B_DROME, 142157_at, RbS5b, CG7014, S5b" "IPR000235=Ribosomal protein S5/S7, IPR020606=Ribosomal protein S7, conserved site, IPR023798=Ribosomal protein S7 domain, IPR005716=Ribosomal protein S5/S7, eukaryotic/archaeal" CG7014 16-Dec-15 2015_12 ENSDARG00000043453(rps5) YJR123W(RPS5) WBGene00004474(rps-5) ENSXETG00000020355(rps5) ENSMUSG00000012848(Rps5) ENSG00000083845(RPS5) "partially lethal - majority die,visible,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "mesothoracic tergum,ganglion mother cell" DRSC16173 I -1.921137249 0.535845581 0.376751955 0.192180571 -0.431933352 -0.83028135 FBgn0084007 CG41442 http://flybase.net/reports/FBgn0084007.html FBan0041442 protein_coding_gene 16-Dec-15 2015_12 FBgn0002447 l(3)S7 lethal (3) S7 http://flybase.net/reports/FBgn0002447.html gene 16-Dec-15 2015_12 lethal FBgn0040989 CG5693 http://flybase.net/reports/FBgn0040989.html protein_coding_gene CG5693 16-Dec-15 2015_12 viable FBgn0001826 l(1)ts1 lethal (1) ts1 http://flybase.net/reports/FBgn0001826.html gene 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,recessive,heat sensitive" "dorsal closure embryo,heat sensitive,embryonic/larval midgut" FBgn0266965 CR45416 http://flybase.net/reports/FBgn0266965.html non_protein_coding_gene CR45416 16-Dec-15 2015_12 FBgn0060733 l(3)S067206b lethal (3) S067206b http://flybase.net/reports/FBgn0060733.html gene 0672/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0046669 anon-38C.26 anon-38C.26 http://flybase.net/reports/FBgn0046669.html gene 38C.26 16-Dec-15 2015_12 FBgn0016631 E(gl)2G Enhancer of glass 2G http://flybase.net/reports/FBgn0016631.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065571 l(2)SH0960 lethal (2) SH0960 http://flybase.net/reports/FBgn0065571.html gene l(2)SH2 0960 16-Dec-15 2015_12 "lethal,recessive" FBgn0013629 l(3)neo29 lethal (3) neo29 http://flybase.net/reports/FBgn0013629.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026056 Rlip Ral interacting protein http://flybase.net/reports/FBgn0026056.html protein_coding_gene "0005096=GTPase activator activity, 0005515=protein binding, 0017160=Ral GTPase binding" "0043547=positive regulation of GTPase activity, 0046578=regulation of Ras protein signal transduction, 0006898=receptor-mediated endocytosis" 0016020=membrane "dRlip, dRalBP, Rlip, CG11622, RLIP, DRLIP, RhoGAP-93B3, dRLIP, D-RLIP, RLIP1" "IPR008936=Rho GTPase activation protein, IPR000198=Rho GTPase-activating protein domain" CG11622 16-Dec-15 2015_12 ENSDARG00000033481 WBGene00011970(rlbp-1) ENSXETG00000004047(ralbp1) ENSMUSG00000024096(Ralbp1) ENSG00000017797(RALBP1) "viable,fertile,visible" trichogen cell FBgn0262235 mir-983-1 mir-983-1 stem loop http://flybase.net/reports/FBgn0262235.html miRNA_gene "CR42942, dme-mir-983-1, 983-1, miR-983, miR-983-1" CR42942 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein" FBgn0035101 p130CAS p130CAS http://flybase.net/reports/FBgn0035101.html protein_coding_gene "0030011=maintenance of cell polarity, 0007016=cytoskeletal anchoring at plasma membrane, 0016337=single organismal cell-cell adhesion, 0007414=axonal defasciculation" 0005925=focal adhesion "Dcas, DCas, p130Cas, CT1293, CG1212" "IPR021901=CAS family, DUF3513, IPR014928=Serine rich protein interaction, IPR001452=SH3 domain" CG1212 16-Dec-15 2015_12 "ENSDARG00000056525(zgc:175192),ENSDARG00000058891(zgc:154043)" "ENSXETG00000015461(NEDD9),ENSXETG00000004699(BCAR1),ENSXETG00000012029(CASS4)" "ENSMUSG00000031955(Bcar1),ENSMUSG00000021365(Nedd9)" "ENSG00000050820(BCAR1),ENSG00000111859(NEDD9)" "fertile,neuroanatomy defective,viable" "embryo,presumptive embryonic/larval central nervous system,intersegmental nerve,segmental nerve" FBgn0267313 CR45749 http://flybase.net/reports/FBgn0267313.html non_protein_coding_gene CR45749 16-Dec-15 2015_12 FBgn0264291 Det Deterin http://flybase.net/reports/FBgn0264291.html "FBgn0259784, FBgn0042948, FBgn0038489, FBgn0083063" protein_coding_gene 0008270=zinc ion binding "0033206=meiotic cytokinesis, 0043066=negative regulation of apoptotic process, 0000915=actomyosin contractile ring assembly, 0007111=meiosis II cytokinesis, 0000281=mitotic cytokinesis, 0045132=meiotic chromosome segregation, 0046331=lateral inhibition, 0022008=neurogenesis, 0090307=mitotic spindle assembly, 0051225=spindle assembly, 0007052=mitotic spindle organization, 0007110=meiosis I cytokinesis" "0032133=chromosome passenger complex, 1990023=mitotic spindle midzone, 0000776=kinetochore, 0005737=cytoplasm, 0000775=chromosome, centromeric region, 1990385=meiotic spindle midzone" "svn, scapolo, Survivin, CG12265, scpo, deterin, dSurvivin" IPR001370=BIR repeat CG12265 16-Dec-15 2015_12 "ENSDARG00000015440,ENSDARG00000055655(birc5b)" WBGene00000249(bir-1) "ENSXETG00000004294(TEgg052f17.1),ENSXETG00000009983(birc5)" ENSMUSG00000017716(Birc5) ENSG00000089685(BIRC5) FBgn0267462 CR45812 http://flybase.net/reports/FBgn0267462.html non_protein_coding_gene CR45812 16-Dec-15 2015_12 FBgn0054025 CG34025 http://flybase.net/reports/FBgn0054025.html FBgn0082658 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "HDC08169, unnamed, BP1082" IPR001810=F-box domain CG34025 16-Dec-15 2015_12 FBgn0014256 l(2)DB4 lethal (2) DB4 http://flybase.net/reports/FBgn0014256.html gene DB4 16-Dec-15 2015_12 "lethal,recessive" FBgn0023431 l(2)M65 lethal (2) M65 http://flybase.net/reports/FBgn0023431.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,mating defective,male" FBgn0260451 CG14042 http://flybase.net/reports/FBgn0260451.html "FBgn0031671, FBgn0031672, FBan0014041, FBgn0040280, FBgn0045318, FBgn0063746" protein_coding_gene "CG14041, NEST:bs13e02" CG14042 16-Dec-15 2015_12 FBgn0035124 ttm2 tiny tim 2 http://flybase.net/reports/FBgn0035124.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0043021=ribonucleoprotein complex binding" "0007005=mitochondrion organization, 0007006=mitochondrial membrane organization, 0015031=protein transport, 0006470=protein dephosphorylation" "0005744=mitochondrial inner membrane presequence translocase complex, 0005739=mitochondrion, 0016607=nuclear speck, 0005743=mitochondrial inner membrane" "20130405, CG12313" "IPR023214=HAD-like domain, IPR027111=Mitochondrial import inner membrane translocase subunit Tim50, IPR004274=FCP1 homology domain" CG12313 16-Dec-15 2015_12 ENSDARG00000031098(timm50) YPL063W(TIM50) WBGene00011897(scpl-4) ENSXETG00000002882(TIMM50) ENSMUSG00000003438(Timm50) ENSG00000105197(TIMM50) viable FBgn0083991 CG34155 http://flybase.net/reports/FBgn0083991.html protein_coding_gene CG34155 16-Dec-15 2015_12 FBgn0085524 CG40844 http://flybase.net/reports/FBgn0085524.html FBan0040844 protein_coding_gene 16-Dec-15 2015_12 FBgn0267243 CR45683 http://flybase.net/reports/FBgn0267243.html non_protein_coding_gene CR45683 16-Dec-15 2015_12 FBgn0028625 l(2)01528 lethal (2) 01528 http://flybase.net/reports/FBgn0028625.html FBgn0010495 gene l(2)38EFg 16-Dec-15 2015_12 "lethal,recessive" FBgn0040476 Cyp12a2 Cytochrome P450-12a2 http://flybase.net/reports/FBgn0040476.html gene CYP12A2 16-Dec-15 2015_12 FBgn0029922 CG14431 http://flybase.net/reports/FBgn0029922.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity 0006357=regulation of transcription from RNA polymerase II promoter 0016592=mediator complex "IPR019087=Mediator complex, subunit Med15" CG14431 16-Dec-15 2015_12 viable FBgn0015772 Nak Numb-associated kinase http://flybase.net/reports/FBgn0015772.html protein_coding_gene "0035612=AP-2 adaptor complex binding, 0004672=protein kinase activity, 0051425=PTB domain binding, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0005515=protein binding" "0006468=protein phosphorylation, 0048813=dendrite morphogenesis, 0008356=asymmetric cell division, 2000369=regulation of clathrin-mediated endocytosis" "0043025=neuronal cell body, 0030424=axon, 0030425=dendrite" "CG10637, nak" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG10637 16-Dec-15 2015_12 YBR059C(AKL1) WBGene00004762(sel-5) "ENSXETG00000008205(AAK1),ENSXETG00000009530()" "ENSMUSG00000034663(Bmp2k),ENSMUSG00000057230(Aak1)" ENSG00000115977(AAK1) " embryonic stage | 0-12hr , embryonic stage -- adult stage , embryonic stage "

ubiquitous "viable,fertile,neuroanatomy defective,recessive,visible" "dendritic arborizing neuron,dendrite | larval stage,dorsal multidendritic neuron ddaC,somatic clone,dendrite | larval stage | somatic clone,dendritic arborizing neuron | larval stage,dendrite | larval stage109(2)80,scolopidial neuron | embryonic stage,wing sensillum,head sensillum,adult mesothoracic sensillum,embryonic/larval salivary gland,dendrite | larval stage | somatic clone477,dendritic spine | larval stage, with Df(2L)TW3, ,dorsal multidendritic neuron ddaA | larval stage,dendrite | larval stage, with Df(2L)TW3, ,dorsal multidendritic neuron ddaE | larval stage,dendrite | larval stageIG1-1" FBgn0085500 CR40601 http://flybase.net/reports/FBgn0085500.html FBan0040601 pseudogene_attribute "CG12717-related, CG40601" CR40601 16-Dec-15 2015_12 FBgn0044412 Scim15 Sensitized chromosome inheritance modifier 15 http://flybase.net/reports/FBgn0044412.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0263342 CR43423 http://flybase.net/reports/FBgn0263342.html non_protein_coding_gene CR43423 16-Dec-15 2015_12 FBgn0032517 CG7099 http://flybase.net/reports/FBgn0032517.html protein_coding_gene "dTFIIIC220, FBgn 32517" IPR007309=B-block binding subunit of TFIIIC CG7099 16-Dec-15 2015_12 ENSMUSG00000032777(Gtf3c1) ENSG00000077235(GTF3C1) "viable,visible" trichogen cell FBgn0263559 mir-2535b mir-2535b stem loop http://flybase.net/reports/FBgn0263559.html miRNA_gene "CR43544, dme-mir-2535b" CR43544 16-Dec-15 2015_12 FBgn0017401 eve::ftz eve::ftz http://flybase.net/reports/FBgn0017401.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0263477 scaRNA:ë¬U1-6 small Cajal body-specific RNA : ë¬U1-6 http://flybase.net/reports/FBgn0263477.html snoRNA_gene "0030559=rRNA pseudouridylation guide activity, 0030565=snRNA pseudouridylation guide activity" 0015030=Cajal body "snoRNA:dmt-a, pugU1-6" CR43592 16-Dec-15 2015_12 FBgn0022396 HelII Helicase II http://flybase.net/reports/FBgn0022396.html gene 0008026=ATP-dependent helicase activity 0032508=DNA duplex unwinding dhel II 16-Dec-15 2015_12 FBgn0036735 Edc3 Enhancer of decapping 3 http://flybase.net/reports/FBgn0036735.html protein_coding_gene "0005875=microtubule associated complex, 0000932=cytoplasmic mRNA processing body" "LSm16, EDC3, LSM16, CG6311, enhancer of decapping 3, enhancer of decapping-3, DmEDC3" "IPR025762=DFDF domain, IPR004443=YjeF N-terminal domain" CG6311 16-Dec-15 2015_12 ENSDARG00000051931(edc3) ENSXETG00000010622(EDC3) ENSMUSG00000038957(Edc3) ENSG00000179151(EDC3) viable FBgn0011848 tRNA:E4:56Fa transfer RNA:glu4:56Fa http://flybase.net/reports/FBgn0011848.html "FBgn0003771, FBgn0011846, FBgn0050453, FBgn0060241" tRNA_gene "0033459=GAA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30453, tRNA:E:TTC:AE002787-a, AE002787.trna4-GluTTC, glu-tRNA-4, tRNA:Glu, chr2R.trna62-GluTTC, tRNA:glu4:56Fa, tRNA:E4" CR30453 16-Dec-15 2015_12 FBgn0267790 rump rumpelstiltskin http://flybase.net/reports/FBgn0267790.html "FBgn0020921, FBgn0260010, FBgn0037701, FBgn0043867" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003730=mRNA 3'-UTR binding" "0007067=mitotic nuclear division, 0009952=anterior/posterior pattern specification, 0045451=pole plasm oskar mRNA localization, 0008298=intracellular mRNA localization, 0008595=anterior/posterior axis specification, embryo, 0035282=segmentation, 0007277=pole cell development" "0030529=ribonucleoprotein complex, 0005737=cytoplasm, 0005634=nucleus, 0000790=nuclear chromatin, 0035062=omega speckle, 0005654=nucleoplasm" "hrp59, p75, cg9373, Rumpelstiltskin, Heterogeneous nuclear ribonucleoprotein S5, Hrp59, S5, hnRNP M, unnamed, heterogeneous nuclear ribonucleoprotein M, CG9373, p70, HnRNP-S5" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG9373 16-Dec-15 2015_12 "ENSDARG00000061735(hnrnpm),ENSDARG00000059398(myef2)" YNL004W(HRB1) WBGene00007706(C25A1.4) "ENSXETG00000018412(TGas143b07.1),ENSXETG00000001777(HNRNPM)" "ENSMUSG00000027201(Myef2),ENSMUSG00000049230(Gm9833),ENSMUSG00000059208(Hnrnpm)" "ENSG00000104177(MYEF2),ENSG00000099783(HNRNPM)" DRSC16480 K -1.123479427 -0.435853837 -0.892071498 -0.271251098 1.733494599 0.171233244 FBgn0086046 snoRNA:Me28S-A1705 http://flybase.net/reports/FBgn0086046.html snoRNA_gene "Me28S-Am1705, CR34675" CR34675 16-Dec-15 2015_12 FBgn0011414 l(3)j9A5 lethal (3) j9A5 http://flybase.net/reports/FBgn0011414.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043477 l(3)66EFi lethal (3) 66EFi http://flybase.net/reports/FBgn0043477.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267025 CR45469 http://flybase.net/reports/FBgn0267025.html non_protein_coding_gene CR45469 16-Dec-15 2015_12 FBgn0005226 l(3)R12 lethal (3) R12 http://flybase.net/reports/FBgn0005226.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039770 CG15537 http://flybase.net/reports/FBgn0039770.html protein_coding_gene "0051424=corticotropin-releasing hormone binding, 0042562=hormone binding" 0042445=hormone metabolic process 0005615=extracellular space IPR008435=Corticotropin-releasing factor-binding protein CG15537 16-Dec-15 2015_12 ENSXETG00000017080(CRHBP) ENSMUSG00000021680(Crhbp) ENSG00000145708(CRHBP) FBgn0261649 tinc tincar http://flybase.net/reports/FBgn0261649.html "FBgn0038554, FBgn0038553, FBgn0038555, FBgn0051247, FBgn0062837, FBgn0051246" protein_coding_gene 0042478=regulation of eye photoreceptor cell development 0005886=plasma membrane "CG14319, CG14320, CG31247, CG31246, Tincar, CG7723" CG31247 16-Dec-15 2015_12 WBGene00044698(K09F5.6) DRSC22723 I -0.757444431 -1.959206401 -0.603882794 -0.655462853 0.975836265 0.628206552 FBgn0027159 l(2)PN-11 lethal (2) PN-11 http://flybase.net/reports/FBgn0027159.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033985 CG10257 http://flybase.net/reports/FBgn0033985.html FBgn0062429 protein_coding_gene "0043066=negative regulation of apoptotic process, 0048812=neuron projection morphogenesis" BcDNA:RH51312 IPR010695=Fas apoptotic inhibitory molecule CG10257 16-Dec-15 2015_12 "ENSDARG00000005828(zgc:92723),ENSDARG00000020814(zgc:92712)" WBGene00016633(C44B11.1) ENSXETG00000007986(Q5RJT9_XENTR) "ENSMUSG00000032463(Faim),ENSMUSG00000079413(Gm6432)" ENSG00000158234(FAIM) viable FBgn0025762 l(3)89En lethal (3) 89En http://flybase.net/reports/FBgn0025762.html gene l(3)M2511 16-Dec-15 2015_12 "lethal,recessive" FBgn0016706 Reg-11 Rhythmically expressed gene 11 http://flybase.net/reports/FBgn0016706.html gene "Drosophila Rhythmically expressed gene 11, Dreg-11" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " adult head

FBgn0022378 Pt-12 Larval protein-12 http://flybase.net/reports/FBgn0022378.html gene 16-Dec-15 2015_12 FBgn0035528 CG15012 http://flybase.net/reports/FBgn0035528.html protein_coding_gene 0004563=beta-N-acetylhexosaminidase activity IPR007919=Uncharacterised protein family UPF0220 CG15012 16-Dec-15 2015_12 ENSDARG00000015757(tmem50a) WBGene00022280(Y74C10AL.2) "ENSXETG00000026802(tmem50a),ENSXETG00000000043(tmem50b)" "ENSMUSG00000028822(Tmem50a),ENSMUSG00000022964(Tmem50b)" "ENSG00000183726(TMEM50A),ENSG00000142188(TMEM50B)" "viable,fertile" FBgn0038467 AdSL Adenylosuccinate Lyase http://flybase.net/reports/FBgn0038467.html protein_coding_gene "0004018=N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity" "0006163=purine nucleotide metabolic process, 0009152=purine ribonucleotide biosynthetic process" 0005829=cytosol "CG3590, AdSL" "IPR019468=Adenylosuccinate lyase C-terminal, IPR008948=L-Aspartase-like, IPR004769=Adenylosuccinate lyase, IPR020557=Fumarate lyase, conserved site, IPR000362=Fumarate lyase family, IPR022761=Fumarate lyase, N-terminal, IPR024083=Fumarase/histidase, N-terminal" CG3590 16-Dec-15 2015_12 ENSDARG00000017049(adsl) YLR359W(ADE13) WBGene00011064(R06C7.5) ENSXETG00000006328(adsl) ENSMUSG00000022407(Adsl) ENSG00000100357 "lethal - all die during larval stage,recessive,long lived,viable" FBgn0010186 tu(3)mt tu(3)mt http://flybase.net/reports/FBgn0010186.html gene mt 16-Dec-15 2015_12 melanotic mass phenotype FBgn0051466 CG31466 http://flybase.net/reports/FBgn0051466.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053379 5SrRNA:CR33379 5SrRNA:CR33379 http://flybase.net/reports/FBgn0053379.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33379 CR33379 16-Dec-15 2015_12 FBgn0267475 CR45825 http://flybase.net/reports/FBgn0267475.html non_protein_coding_gene CR45825 16-Dec-15 2015_12 FBgn0038481 CG17475 http://flybase.net/reports/FBgn0038481.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP131 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG17475 16-Dec-15 2015_12 viable FBgn0267758 CR46089 http://flybase.net/reports/FBgn0267758.html non_protein_coding_gene CR46089 16-Dec-15 2015_12 FBgn0039566 CG4849 http://flybase.net/reports/FBgn0039566.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003746=translation elongation factor activity" "0070374=positive regulation of ERK1 and ERK2 cascade, 0006414=translational elongation, 0046579=positive regulation of Ras protein signal transduction, 0000398=mRNA splicing, via spliceosome" "0005737=cytoplasm, 0005829=cytosol, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0071013=catalytic step 2 spliceosome, 0005682=U5 snRNP" "EFTUD2, eftud2, eEF2, Snu114" "IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR005225=Small GTP-binding protein domain, IPR005517=Translation elongation factor EFG/EF2, domain IV, IPR000640=Translation elongation factor EFG, V domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR009022=Elongation factor G, III-V domain, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR020568=Ribosomal protein S5 domain 2-type fold" CG4849 16-Dec-15 2015_12 ENSDARG00000012261(eftud2) WBGene00001166(eft-1) ENSXETG00000003394(Q5BL79_XENTR) ENSMUSG00000020929(Eftud2) ENSG00000108883(EFTUD2) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC27175 EK 0.257350051 -0.020714416 -2.861726768 0.631922756 -2.421490211 -1.551048014 FBgn0060935 l(3)S041316a lethal (3) S041316a http://flybase.net/reports/FBgn0060935.html gene 0413/16 16-Dec-15 2015_12 "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0259355 EP-J59 http://flybase.net/reports/FBgn0259355.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta" FBgn0010061 M(2)34b M(2)34b http://flybase.net/reports/FBgn0010061.html gene 16-Dec-15 2015_12 FBgn0013749 Arf102F ADP ribosylation factor at 102F http://flybase.net/reports/FBgn0013749.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003956=NAD(P)+-protein-arginine ADP-ribosyltransferase activity" "0015031=protein transport, 0016197=endosomal transport, 0048749=compound eye development, 0006471=protein ADP-ribosylation, 0007264=small GTPase mediated signal transduction, 0048488=synaptic vesicle endocytosis, 0007269=neurotransmitter secretion" 0005622=intracellular "ARF2, CG11027, P40945, Arf4, ARFII, Arf5, unnamed, dARFII, ADP ribosylation factor II, ADP ribosylation factor 102F, Arf102E, arf102F" "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR024156=Small GTPase superfamily, ARF type" CG11027 16-Dec-15 2015_12 "ENSDARG00000042382(zgc:77650),ENSDARG00000045989(zgc:101030)" WBGene00000183(arf-3) ENSXETG00000008654(arf4) "ENSMUSG00000020440(Arf5),ENSMUSG00000021877(Arf4)" "ENSG00000004059(ARF5),ENSG00000168374(ARF4)" adult stage lethal eye DRSC17195 E 0.018030843 -0.366383828 -0.531037611 -2.163472001 0.535574887 1.141903728 FBgn0030720 CG8939 http://flybase.net/reports/FBgn0030720.html protein_coding_gene 0008649=rRNA methyltransferase activity "0040018=positive regulation of multicellular organism growth, 0031167=rRNA methylation, 0006364=rRNA processing" 0005730=nucleolus dSpb1 "IPR028589=AdoMet-dependent rRNA methyltransferase, Spb1, IPR024576=Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381, IPR002877=Ribosomal RNA methyltransferase FtsJ domain, IPR012920=Ribosomal RNA methyltransferase, Spb1, C-terminal, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR015507=Ribosomal RNA large subunit methyltransferase E" CG8939 16-Dec-15 2015_12 YCL054W(SPB1) WBGene00019168(H06I04.3) ENSXETG00000006939(FTSJ3) ENSMUSG00000020706(Ftsj3) ENSG00000108592(FTSJ3) viable FBgn0082344 HM505 HM505 http://flybase.net/reports/FBgn0082344.html gene 16-Dec-15 2015_12 FBgn0030018 slpr slipper http://flybase.net/reports/FBgn0030018.html FBgn0026171 protein_coding_gene "0005524=ATP binding, 0042803=protein homodimerization activity, 0004712=protein serine/threonine/tyrosine kinase activity, 0004706=JUN kinase kinase kinase activity, 0004672=protein kinase activity" "0007257=activation of JUN kinase activity, 0071361=cellular response to ethanol, 0007256=activation of JNKK activity, 0046529=imaginal disc fusion, thorax closure, 0007394=dorsal closure, elongation of leading edge cells, 0048803=imaginal disc-derived male genitalia morphogenesis, 0046843=dorsal appendage formation, 0009408=response to heat, 0007391=dorsal closure, 0048804=imaginal disc-derived female genitalia morphogenesis, 0007254=JNK cascade, 0046777=protein autophosphorylation, 0006468=protein phosphorylation, 0046330=positive regulation of JNK cascade" 0005938=cell cortex "JNKKK, Slpr, Mixed lineage protein kinase 2, Slipper, CG2272, dMLK2, MLK, Mlk2, MLK2, dMLK, D-MLK" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001452=SH3 domain, IPR008271=Serine/threonine-protein kinase, active site" CG2272 16-Dec-15 2015_12 ENSXETG00000007519() " embryonic stage , adult stage , embryonic stage | early , embryonic stage&&adult stage " "

ubiquitous , head && thorax

, organism

" "visible,heat stress response defective,male,female,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal,recessive,rescuable maternal effect,partially,lethal - all die during embryonic stage,long lived,partially lethal - majority live,short lived,partially lethal - majority die,some die during pupal stage" "scutellum,scutellar bristle,embryonic/first instar larval cuticle,dorsal,adult thorax,mesothoracic tergum,embryonic dorsal epidermis,maxillary palpus,female terminalia,adult external thorax,dorsal closure embryo,rescuable maternal effect,embryonic leading edge cell,dorsal appendage,maternal effect,somatic clone,dorsal ectoderm,wing,male terminalia,adult abdominal segment" FBgn0263455 CR43478 http://flybase.net/reports/FBgn0263455.html non_protein_coding_gene CR43478 16-Dec-15 2015_12 FBgn0034786 CG13531 http://flybase.net/reports/FBgn0034786.html protein_coding_gene "IPR028103=Spatacsin, IPR028107=Spatacsin, C-terminal domain" CG13531 16-Dec-15 2015_12 ENSMUSG00000033396 ENSG00000104133(SPG11) "viable,fertile" FBgn0053398 5SrRNA:CR33398 5SrRNA:CR33398 http://flybase.net/reports/FBgn0053398.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33398 CR33398 16-Dec-15 2015_12 FBgn0015787 Ppi-16 Protein phosphatase 1 Interacting protein clone-16 http://flybase.net/reports/FBgn0015787.html gene 0008157=protein phosphatase 1 binding 16-Dec-15 2015_12 FBgn0053439 5SrRNA:CR33439 5SrRNA:CR33439 http://flybase.net/reports/FBgn0053439.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33439 CR33439 16-Dec-15 2015_12 FBgn0262434 mir-11 mir-11 stem loop http://flybase.net/reports/FBgn0262434.html "FBgn0046832, FBgn0262285" miRNA_gene "0060548=negative regulation of cell death, 0071480=cellular response to gamma radiation, 0043066=negative regulation of apoptotic process" "11, miR-11, mir-11, CR42992, CR32929, Dme-miR-11, dme-mir-11, MiR-11, dme-miR-11" CR42992 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0033873 CG6337 http://flybase.net/reports/FBgn0033873.html protein_coding_gene 0004197=cysteine-type endopeptidase activity 0006508=proteolysis "IPR000668=Peptidase C1A, papain C-terminal, IPR013128=Peptidase C1A, IPR013201=Cathepsin propeptide inhibitor domain (I29)" CG6337 16-Dec-15 2015_12 viable FBgn0010022 E(Dl)D165 Enhancer of Delta D165 http://flybase.net/reports/FBgn0010022.html gene 16-Dec-15 2015_12 FBgn0038800 CG15921 http://flybase.net/reports/FBgn0038800.html protein_coding_gene 16-Dec-15 2015_12 FBgn0021996 l(2)k09501 lethal (2) k09501 http://flybase.net/reports/FBgn0021996.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031785 CG13991 http://flybase.net/reports/FBgn0031785.html protein_coding_gene CG13991 16-Dec-15 2015_12 FBgn0003563 Su(Gl)27 Suppressor of Glued 27 http://flybase.net/reports/FBgn0003563.html gene "Su(Gl), Suppressor of Glued" 16-Dec-15 2015_12 FBgn0259275 GS-C31 http://flybase.net/reports/FBgn0259275.html gene C31 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0041615 SM3-8 SM3-8 http://flybase.net/reports/FBgn0041615.html gene 16-Dec-15 2015_12 FBgn0033851 CG13332 http://flybase.net/reports/FBgn0033851.html protein_coding_gene CG13332 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0067059 P316 P316 http://flybase.net/reports/FBgn0067059.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0039755 CG15531 http://flybase.net/reports/FBgn0039755.html protein_coding_gene 0004768=stearoyl-CoA 9-desaturase activity "0006629=lipid metabolic process, 0055114=oxidation-reduction process" "IPR005804=Fatty acid desaturase domain, IPR015876=Fatty acid desaturase, type 1, core" CG15531 16-Dec-15 2015_12 viable FBgn0262021 CG42832 http://flybase.net/reports/FBgn0262021.html protein_coding_gene CG42832 16-Dec-15 2015_12 FBgn0259668 B2038 http://flybase.net/reports/FBgn0259668.html gene 16-Dec-15 2015_12 visible "1st posterior cell,wing,wing sensillum,ectopic,wing vein,chaeta" FBgn0032166 CG4619 http://flybase.net/reports/FBgn0032166.html FBgn0051879 protein_coding_gene CG31879 CG4619 16-Dec-15 2015_12 viable FBgn0032223 GATAd GATAd http://flybase.net/reports/FBgn0032223.html protein_coding_gene "0008270=zinc ion binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "dGATAd, CG5034, dGATA-D" "IPR000679=Zinc finger, GATA-type, IPR013088=Zinc finger, NHR/GATA-type, IPR012934=Zinc finger, AD-type" CG5034 16-Dec-15 2015_12 YMR136W(GAT2) "WBGene00001253(elt-6),WBGene00001186(egl-18)" FBgn0052457 CG32457 http://flybase.net/reports/FBgn0052457.html FBan0032457 protein_coding_gene CG32457 16-Dec-15 2015_12 "viable,fertile" FBgn0034578 CG15653 http://flybase.net/reports/FBgn0034578.html protein_coding_gene IPR014807=Cytochrome oxidase assembly protein 1 CG15653 16-Dec-15 2015_12 ENSG00000106603(C7orf44) viable FBgn0016837 l(1)MZ5 lethal (1) MZ5 http://flybase.net/reports/FBgn0016837.html gene M5 16-Dec-15 2015_12 "lethal,recessive" FBgn0038185 CG14363 http://flybase.net/reports/FBgn0038185.html protein_coding_gene 16-Dec-15 2015_12 DRSC25183 K -0.597533226 0.144497612 0.798615875 -0.00056561 1.661396032 1.017633884 FBgn0022166 l(2)45Bc lethal (2) 45Bc http://flybase.net/reports/FBgn0022166.html FBgn0015479 gene "l(2)k05611, l(2)k05611b, l(2)k05611a" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0034928 CG13562 http://flybase.net/reports/FBgn0034928.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG13562 16-Dec-15 2015_12 FBgn0010838 l(3)04281 lethal (3) 04281 http://flybase.net/reports/FBgn0010838.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0085206 CG34177 http://flybase.net/reports/FBgn0085206.html protein_coding_gene 0005615=extracellular space CG12677 IPR029277=Single domain Von Willebrand factor type C domain CG34177 16-Dec-15 2015_12 FBgn0082674 Fas1::kirre Fas1::kirre http://flybase.net/reports/FBgn0082674.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0053810 His1:CG33810 His1:CG33810 http://flybase.net/reports/FBgn0053810.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33810 "IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15" CG33810 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0022052 l(2)k08201 lethal (2) k08201 http://flybase.net/reports/FBgn0022052.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036301 CG4069 http://flybase.net/reports/FBgn0036301.html FBgn0046374 protein_coding_gene anon-WO0172774.58 "IPR011498=Kelch repeat type 2, IPR015915=Kelch-type beta propeller" CG4069 16-Dec-15 2015_12 ENSDARG00000017730(klhdc4) YPL263C(KEL3) ENSXETG00000017380(KLHDC4) ENSMUSG00000040263(Klhdc4) ENSG00000104731(KLHDC4) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0023395 Chd3 Chd3 http://flybase.net/reports/FBgn0023395.html protein_coding_gene "0005524=ATP binding, 0004003=ATP-dependent DNA helicase activity, 0008270=zinc ion binding, 0070615=nucleosome-dependent ATPase activity, 0003682=chromatin binding, 0003677=DNA binding, 0031491=nucleosome binding, 0004386=helicase activity" "0042766=nucleosome mobilization, 0006333=chromatin assembly or disassembly" "0035327=transcriptionally active chromatin, 0005634=nucleus" "CG9594, dCHD3, chd3, DmCHD3, CHD3, CHD-3" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR009463=Domain of unknown function DUF1087, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR019787=Zinc finger, PHD-finger, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR001965=Zinc finger, PHD-type, IPR023780=Chromo domain, IPR000330=SNF2-related, N-terminal domain, IPR001650=Helicase, C-terminal" CG9594 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0005332 pilX pilosus on X chromosome http://flybase.net/reports/FBgn0005332.html gene "pilosus on X, pil-X" 16-Dec-15 2015_12 abdominal sternite 6 FBgn0004484 l(1)air11 lethal aberrant immune response 11 http://flybase.net/reports/FBgn0004484.html gene "l(1)air[11], air11" 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval lymph gland" FBgn0044348 l(2)a4 lethal (2) a4 http://flybase.net/reports/FBgn0044348.html gene 16-Dec-15 2015_12 lethal FBgn0028334 l(1)G0273 lethal (1) G0273 http://flybase.net/reports/FBgn0028334.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027097 31B8 31B8 http://flybase.net/reports/FBgn0027097.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 border follicle cell FBgn0052835 CR32835 http://flybase.net/reports/FBgn0052835.html FBgn0045271 non_protein_coding_gene "NEST:bs16h07, CG32835" CR32835 16-Dec-15 2015_12 FBgn0029148 NHP2 NHP2 http://flybase.net/reports/FBgn0029148.html FBgn0036452 protein_coding_gene 0030515=snoRNA binding "0009267=cellular response to starvation, 0031118=rRNA pseudouridine synthesis" "0005730=nucleolus, 0005732=small nucleolar ribonucleoprotein complex" "CG5258, FBgn0029148" "IPR029064=50S ribosomal protein L30e-like, IPR018492=Ribosomal protein L7Ae/L8/Nhp2 family, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45" CG5258 16-Dec-15 2015_12 ENSDARG00000069422(nhp2) YDL208W(NHP2) WBGene00012964(Y48A6B.3) ENSXETG00000006731(nola2) ENSMUSG00000001056(Nhp2) ENSG00000145912(NHP2) "viable,visible" trichogen cell DRSC24264 K -0.31946564 0.155569324 0.104863437 0.72879674 0.671270179 1.538756541 FBgn0010113 hdc headcase http://flybase.net/reports/FBgn0010113.html FBgn0013599 protein_coding_gene "0050768=negative regulation of neurogenesis, 0035071=salivary gland cell autophagic cell death, 0035155=negative regulation of terminal cell fate specification, open tracheal system, 0007430=terminal branching, open tracheal system, 0007476=imaginal disc-derived wing morphogenesis, 0007424=open tracheal system development, 0048675=axon extension, 0030154=cell differentiation, 0022008=neurogenesis, 0016246=RNA interference, 0035147=branch fusion, open tracheal system" 0005737=cytoplasm "Headcase, CG15532, l(3)B4-3-20, headcase, psg12, Hdc, Fusion-6" IPR026066=Headcase protein CG15532 16-Dec-15 2015_12 ENSDARG00000042877(heca) ENSMUSG00000039879(Heca) ENSG00000112406(HECA) " embryonic stage--larval stage , embryonic stage " " imaginal disc

, embryonic/larval spiracular branch

, imaginal ring

, embryonic central nervous system

, imaginal disc | primordia

, imaginal tracheoblast

, histoblast

" embryonic stage " imaginal tracheoblast

, imaginal disc

, embryonic/larval ventral anastomosis

, imaginal ring

, embryonic/larval dorsal anastomosis

, histoblast

" "female sterile,lethal,recessive,neuroanatomy defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,phototaxis defective,viable,visible" "embryonic/larval salivary gland,embryonic/larval trachea,axon | somatic clone | third instar larval stage,rhabdomere,somatic clone,head,antenna,head & cuticle,central nervous system,somatic muscle,tracheal system,wing,haltere,leg,epidermis,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,dorsal branch | embryonic stage,dorsal branch | third instar larval stage,tracheole" FBgn0024601 rambl rambling http://flybase.net/reports/FBgn0024601.html gene 0007411=axon guidance 16-Dec-15 2015_12 viable Bolwig nerve FBgn0040261 Ugt36Bb Ugt36Bb http://flybase.net/reports/FBgn0040261.html FBgn0032605 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG13271, AC 005121B" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG13271 16-Dec-15 2015_12 "WBGene00011006(ugt-47),WBGene00011564(ugt-50),WBGene00015141(ugt-46),WBGene00015965(ugt-48),WBGene00007070(ugt-49)" viable FBgn0265668 CG44475 http://flybase.net/reports/FBgn0265668.html protein_coding_gene CG44475 16-Dec-15 2015_12 FBgn0028102 l(3)S072611 lethal (3) S072611 http://flybase.net/reports/FBgn0028102.html gene 0726/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0015450 l(1)9Fj lethal (1) 9Fj http://flybase.net/reports/FBgn0015450.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060339 l(3)S144301b lethal (3) S144301b http://flybase.net/reports/FBgn0060339.html gene 1443/01 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024737 Mob Modifier of B1-12 http://flybase.net/reports/FBgn0024737.html gene Mob[1] 16-Dec-15 2015_12 "lethal,recessive" FBgn0039520 Gr98a Gustatory receptor 98a http://flybase.net/reports/FBgn0039520.html FBgn0041220 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "GR98a, Gr98B4, CG13976, 98B.4, GR98B.4, Gustatory receptor 98B.4" IPR013604=7TM chemoreceptor CG13976 16-Dec-15 2015_12 viable FBgn0032840 sNPF short neuropeptide F precursor http://flybase.net/reports/FBgn0032840.html protein_coding_gene "0005184=neuropeptide hormone activity, 0005179=hormone activity, 0071855=neuropeptide receptor binding" "0040018=positive regulation of multicellular organism growth, 0035264=multicellular organism growth, 0007218=neuropeptide signaling pathway, 0045793=positive regulation of cell size, 0008340=determination of adult lifespan, 0007623=circadian rhythm, 0090062=regulation of trehalose metabolic process, 0070374=positive regulation of ERK1 and ERK2 cascade, 0030536=larval feeding behavior, 0008343=adult feeding behavior, 0046628=positive regulation of insulin receptor signaling pathway, 0010906=regulation of glucose metabolic process" "0030424=axon, 0043025=neuronal cell body, 0005615=extracellular space" "sNPF3, small neuropeptide F-1, sNPF-2[12-19], Short Neuropeptide F, snpf, short neuropeptide F1, lrlrfa, sNPF-4, Drm-sNPF-1, Neuropeptide F (short), sNPF-1[4-11], small neuropeptide F, sNPF-1, short neuropeptide F, sNPF-2, sNPF1, small neuropeptide-F, LRLRFamide, short neuropeptide F-1, Drm-sNPF-2, SNPF, short NPF, sNPF-3, CG13968, LRLRFamides, Drm-sNPF, Drm-sNPF-AP1, Short neuropeptide F, sNPF precursor, Drm-sNPF-4, precursor of short neuropeptide F, Short NPF, sNPF-2s, s-NPF, Drm-sNPF-3, 38B.2" CG13968 16-Dec-15 2015_12 "large body,small body,decreased cell size,feeding behavior defective,long lived,locomotor behavior defective,male,female,increased cell size" embryonic/larval fat body FBgn0026714 kub kubel http://flybase.net/reports/FBgn0026714.html gene 0007417=central nervous system development 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,commissure,midline glial cell,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0040140 l(1)G0490 lethal (1) G0490 http://flybase.net/reports/FBgn0040140.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050460 CG30460 http://flybase.net/reports/FBgn0050460.html "FBgn0034188, FBgn0034189, FBgn0044633" protein_coding_gene "anon-WO0140519.237, CG15608, CG15607" IPR026319=Zinc finger C2HC domain-containing protein CG30460 16-Dec-15 2015_12 viable FBgn0020852 ful fuliginosus http://flybase.net/reports/FBgn0020852.html gene 16-Dec-15 2015_12 "visible,recessive,body color defective" wing FBgn0061484 rover\env env http://flybase.net/reports/FBgn0061484.html transposable_element_gene 16-Dec-15 2015_12 FBgn0011052 l(1)Q5 lethal (1) Q5 http://flybase.net/reports/FBgn0011052.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0065092 snmRNA:438 small non-messenger RNA 438 http://flybase.net/reports/FBgn0065092.html FBgn0053660 non_protein_coding_gene "Dm-438, CR33660" CR33660 16-Dec-15 2015_12 FBgn0065811 l(2)SH0384 lethal (2) SH0384 http://flybase.net/reports/FBgn0065811.html gene l(2)SH2 0384 16-Dec-15 2015_12 "lethal,recessive" FBgn0000046 Act87E Actin 87E http://flybase.net/reports/FBgn0000046.html FBgn0038154 protein_coding_gene 0005200=structural constituent of cytoskeleton "0016573=histone acetylation, 0007010=cytoskeleton organization, 0043486=histone exchange" "0035267=NuA4 histone acetyltransferase complex, 0005884=actin filament, 0005811=lipid particle" "Actin, actin87E, actin 87E, mus87E, Actin87E, act87E, CG18290, Act87e, actin, E, act 87E" "IPR004001=Actin, conserved site, IPR004000=Actin family, IPR020902=Actin/actin-like conserved site" CG18290 16-Dec-15 2015_12 YFL039C(ACT1) larval stage larval muscle system

FBgn0085062 EP1324 EP1324 http://flybase.net/reports/FBgn0085062.html gene 16-Dec-15 2015_12 FBgn0050493 CG30493 http://flybase.net/reports/FBgn0050493.html protein_coding_gene 0006744=ubiquinone biosynthetic process 0005743=mitochondrial inner membrane CG1952 "IPR012762=Ubiquinone biosynthesis protein COQ9, IPR013718=COQ9" CG30493 16-Dec-15 2015_12 ENSDARG00000023583(coq9) YLR201C(COQ9) ENSXETG00000025042(Q5RJV0_XENTR) ENSMUSG00000031782(Coq9) ENSG00000088682(COQ9) viable FBgn0039347 CG5071 http://flybase.net/reports/FBgn0039347.html FBgn0064984 protein_coding_gene "0003755=peptidyl-prolyl cis-trans isomerase activity, 0008270=zinc ion binding" "0006457=protein folding, 0000413=protein peptidyl-prolyl isomerization" 0005622=intracellular BcDNA:AT31683 "IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR017907=Zinc finger, RING-type, conserved site, IPR000315=B-box-type zinc finger, IPR029000=Cyclophilin-like domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain" CG5071 16-Dec-15 2015_12 viable FBgn0036487 Prp31 http://flybase.net/reports/FBgn0036487.html FBgn0025957 protein_coding_gene "0044822=poly(A) RNA binding, 0043021=ribonucleoprotein complex binding" "0000244=spliceosomal tri-snRNP complex assembly, 0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005681=spliceosomal complex, 0046540=U4/U6 x U5 tri-snRNP complex" "anon-EST:Liang-2.38, FBgn0036487, clone 2.38, CG6876" "IPR027105=U4/U6 small nuclear ribonucleoprotein Prp31, IPR012976=NOSIC, IPR019175=Prp31 C-terminal, IPR002687=Nop domain" CG6876 16-Dec-15 2015_12 "ENSDARG00000029114(prpf31),ENSDARG00000069886" YGR091W(PRP31) WBGene00022458(Y110A7A.8) ENSXETG00000010916(prpf31) ENSMUSG00000008373(Prpf31) ENSG00000105618(PRPF31) "visible,lethal,neuroanatomy defective,partially lethal - majority die" "eye,rhabdomereey.PU,pigment cell,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC10735 E 1.376649186 0.684422679 -0.27098361 2.017759526 -0.432992994 -0.917730992 FBgn0266641 CR45148 http://flybase.net/reports/FBgn0266641.html non_protein_coding_gene lincRNA.368 CR45148 16-Dec-15 2015_12 FBgn0263912 piRNA piwi-associated RNA http://flybase.net/reports/FBgn0263912.html gene_group "PIWI-interacting RNA, Piwi-interacting RNA" 16-Dec-15 2015_12 FBgn0029679 CG2901 http://flybase.net/reports/FBgn0029679.html protein_coding_gene 0008039=synaptic target recognition 0016021=integral component of membrane "IPR004342=EXS, C-terminal, IPR004331=SPX domain" CG2901 16-Dec-15 2015_12 YIL047C(SYG1) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0259245 DIP-ë_ Dpr-interacting protein ë_ http://flybase.net/reports/FBgn0259245.html "FBgn0031179, FBgn0031180, FBgn0047148, FBgn0040644, FBgn0054019, FBgn0082844" protein_coding_gene "CG42343, pp-CT34319, CG14583, pp-CT34321, CG12564, DIP-beta, 42343, CG12565, unnamed, CG34019, pp-CT34320, BP1062, CT34319, BcDNA:RE23430" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG42343 16-Dec-15 2015_12 WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" FBgn0060326 l(3)S146604b lethal (3) S146604b http://flybase.net/reports/FBgn0060326.html gene 1466/04 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0015886 anon-66Ba anon-66Ba http://flybase.net/reports/FBgn0015886.html gene 16-Dec-15 2015_12 FBgn0039354 Lgr3 Leucine-rich repeat-containing G protein-coupled receptor 3 http://flybase.net/reports/FBgn0039354.html "FBgn0039353, FBgn0046546, FBgn0046547, FBgn0051096" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity, 0016500=protein-hormone receptor activity" "0019933=cAMP-mediated signaling, 0007186=G-protein coupled receptor signaling pathway" 0016021=integral component of membrane "dLGR3, CT16193, anon-WO0170980.26, CG5042, CG31096, DLGR3, Lgr3, CG5046, anon-WO0170980.25" "IPR001611=Leucine-rich repeat, IPR017452=GPCR, rhodopsin-like, 7TM, IPR008112=Relaxin receptor, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002131=Glycoprotein hormone receptor family, IPR003591=Leucine-rich repeat, typical subtype, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat" CG31096 16-Dec-15 2015_12 "ENSDARG00000071376,ENSDARG00000032820(rxfp2)" "ENSXETG00000011511(),ENSXETG00000019493(RXFP1),ENSXETG00000019186(RXFP2)" "ENSMUSG00000053368(Rxfp2),ENSMUSG00000034009(Rxfp1)" "ENSG00000133105(RXFP2),ENSG00000171509(RXFP1)" FBgn0005208 l(3)gl lethal (3) giant larvae http://flybase.net/reports/FBgn0005208.html gene l(3)giant larvae 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "fat body,embryonic/larval brain,imaginal disc" FBgn0065530 l(2)SH1110 lethal (2) SH1110 http://flybase.net/reports/FBgn0065530.html gene l(2)SH2 1110 16-Dec-15 2015_12 "lethal,recessive" FBgn0052218 CR32218 http://flybase.net/reports/FBgn0052218.html FBgn0036914 non_protein_coding_gene CG8037 CR32218 16-Dec-15 2015_12 FBgn0041090 upd-like upd-like http://flybase.net/reports/FBgn0041090.html gene 16-Dec-15 2015_12 FBgn0026160 tna tonalli http://flybase.net/reports/FBgn0026160.html "FBgn0011498, FBgn0024566, FBgn0028123, FBgn0036103, FBgn0061852" protein_coding_gene 0008270=zinc ion binding 0048096=chromatin-mediated maintenance of transcription 0000790=nuclear chromatin "unnamed, anon-WO0118547.590, Tonalli A, l(3)rI075, 0583/02, l(3)S058302, l(3)L6731, CG7958" "IPR004181=Zinc finger, MIZ-type" CG7958 16-Dec-15 2015_12 WBGene00011259(miz-1) "ENSXETG00000018991(ZMIZ2),ENSXETG00000018359(ZMIZ1)" "ENSMUSG00000041164(Zmiz2),ENSMUSG00000007817(Zmiz1)" "ENSG00000122515(ZMIZ2),ENSG00000108175(ZMIZ1)" "visible,lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,dominant,viable" "sex comb,haltere,wing,ectopic,mesothoracic tergum" FBgn0043825 CG18284 http://flybase.net/reports/FBgn0043825.html FBgn0032274 protein_coding_gene "0016298=lipase activity, 0016788=hydrolase activity, acting on ester bonds" "0032504=multicellular organism reproduction, 0006629=lipid metabolic process" 0005615=extracellular space "Acp, BEST:GH10507" "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG18284 16-Dec-15 2015_12 ENSDARG00000018529(lipf) "YLR020C(YEH2),YLL012W(YEH1)" "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" DRSC02661 K 0.954721466 0.326033149 -0.700589086 0.302347587 -0.895418467 -1.756131656 FBgn0085508 CG40682 http://flybase.net/reports/FBgn0085508.html FBan0040682 protein_coding_gene 16-Dec-15 2015_12 FBgn0017396 l(1)10Bq lethal (1) 10Bq http://flybase.net/reports/FBgn0017396.html gene HM10 16-Dec-15 2015_12 "lethal,recessive" FBgn0263876 J16 http://flybase.net/reports/FBgn0263876.html gene 16-Dec-15 2015_12 "neuroanatomy defective,somatic clone" "embryonic/larval neuroblast,somatic clone,embryonic/larval brain" FBgn0265729 CR44536 http://flybase.net/reports/FBgn0265729.html non_protein_coding_gene "incRNA.417, lincRNA.417" CR44536 16-Dec-15 2015_12 FBgn0083280 E(smoDN)2281 Enhancer of smoDN 2281 http://flybase.net/reports/FBgn0083280.html gene 16-Dec-15 2015_12 FBgn0086419 l(3)CHc lethal (3) CHc http://flybase.net/reports/FBgn0086419.html gene complementation group 5 16-Dec-15 2015_12 "lethal,recessive" FBgn0041617 SM3-3 SM3-3 http://flybase.net/reports/FBgn0041617.html gene 16-Dec-15 2015_12 FBgn0015464 l(2)37Dl lethal (2) 37Dl http://flybase.net/reports/FBgn0015464.html gene "l(2)E34M, l(2)E34" 16-Dec-15 2015_12 "lethal,recessive" FBgn0263454 CR43477 http://flybase.net/reports/FBgn0263454.html non_protein_coding_gene CR43477 16-Dec-15 2015_12 FBgn0260244 GSd324 http://flybase.net/reports/FBgn0260244.html gene 16-Dec-15 2015_12 lethal FBgn0267686 CR46022 http://flybase.net/reports/FBgn0267686.html non_protein_coding_gene CR46022 16-Dec-15 2015_12 FBgn0065515 l(2)SH1155 lethal (2) SH1155 http://flybase.net/reports/FBgn0065515.html gene l(2)SH2 1155 16-Dec-15 2015_12 "lethal,recessive" FBgn0020878 anon-A34 anon-A34 http://flybase.net/reports/FBgn0020878.html gene 2-A34 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0010862 l(3)05241 lethal (3) 05241 http://flybase.net/reports/FBgn0010862.html gene unnamed 16-Dec-15 2015_12 partially lethal - majority die FBgn0015232 GpHLH Glial precursor HLH protein http://flybase.net/reports/FBgn0015232.html gene 0003700=sequence-specific DNA binding transcription factor activity 0005634=nucleus GPHLH 16-Dec-15 2015_12 FBgn0015992 l(2)k05422a lethal (2) k05422a http://flybase.net/reports/FBgn0015992.html gene l(2)k05422 16-Dec-15 2015_12 "lethal,recessive" presumptive embryonic/larval peripheral nervous system FBgn0031038 Tyler Tyler http://flybase.net/reports/FBgn0031038.html FBgn0053075 protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "CG33075, CG14208" "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG14208 16-Dec-15 2015_12 YGR257C(MTM1) WBGene00007622(C16C10.1) "ENSXETG00000027655(BC075453.1),ENSXETG00000011613(BC088076.1)" "ENSMUSG00000054099(Slc25a40),ENSMUSG00000018677(Slc25a39)" "ENSG00000075303(SLC25A40),ENSG00000013306(SLC25A39)" FBgn0036940 obst-J obstructor-J http://flybase.net/reports/FBgn0036940.html FBgn0026284 protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region "anon-EST:ParkEST360, CG7348" IPR002557=Chitin binding domain CG7348 16-Dec-15 2015_12 viable FBgn0036793 CG4174 http://flybase.net/reports/FBgn0036793.html protein_coding_gene "0005506=iron ion binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" "IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR011990=Tetratricopeptide-like helical domain, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG4174 16-Dec-15 2015_12 FBgn0053360 5SrRNA:CR33360 5SrRNA:CR33360 http://flybase.net/reports/FBgn0053360.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33360 CR33360 16-Dec-15 2015_12 FBgn0041712 yellow-d yellow-d http://flybase.net/reports/FBgn0041712.html "FBgn0034855, FBgn0063234" protein_coding_gene 0016853=isomerase activity "0042438=melanin biosynthetic process, 0048067=cuticle pigmentation" 0005576=extracellular region "yell-d, CG9889, Yellow-d, BcDNA:GH20107, d" "IPR017996=Major royal jelly protein/Protein yellow, IPR011042=Six-bladed beta-propeller, TolB-like" CG9889 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0263962 BG01701 http://flybase.net/reports/FBgn0263962.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0015460 l(2)37CDe lethal (2) 37CDe http://flybase.net/reports/FBgn0015460.html gene l(2)E107 16-Dec-15 2015_12 "lethal,recessive" FBgn0036795 CG18233 http://flybase.net/reports/FBgn0036795.html protein_coding_gene "0005506=iron ion binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016491=oxidoreductase activity, 0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" "0032504=multicellular organism reproduction, 0055114=oxidation-reduction process" 0005783=endoplasmic reticulum "IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG18233 16-Dec-15 2015_12 viable FBgn0028262 l(2)k16716 lethal (2) k16716 http://flybase.net/reports/FBgn0028262.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040360 CG14626 http://flybase.net/reports/FBgn0040360.html FBgn0029565 protein_coding_gene EG:BACR42I17.6 CG14626 16-Dec-15 2015_12 viable FBgn0001227 Hsp67Ba Heat shock gene 67Ba http://flybase.net/reports/FBgn0001227.html FBgn0026837 protein_coding_gene 0009408=response to heat "DmHsp67, small hsp locus 67B, CG4167, Hsp-G1, hsp67Ba, DROHSP1, Gene 1, gene 1, DROHSP, gene1" "IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain, IPR031107=Small heat shock protein HSP20, IPR008978=HSP20-like chaperone" CG4167 16-Dec-15 2015_12 "ENSDARG00000041065(hspb1),ENSDARG00000058362(LOC100331249),ENSDARG00000052447(cryabb),ENSDARG00000058365(hspb8)" "WBGene00004798(sip-1),WBGene00002020(hsp-16.49),WBGene00002015(hsp-16.1),WBGene00002018(hsp-16.41),WBGene00002016(hsp-16.2),WBGene00008592(F08H9.4)" prepupal stage "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0259872 Su(Ste):CR42441 Su(Ste):CR42441 http://flybase.net/reports/FBgn0259872.html non_protein_coding_gene CR42441 CR42441 16-Dec-15 2015_12 FBgn0029113 Uba2 Ubiquitin activating enzyme 2 http://flybase.net/reports/FBgn0029113.html "FBgn0024190, FBgn0035840, FBgn0040287" protein_coding_gene "0019948=SUMO activating enzyme activity, 0033134=ubiquitin activating enzyme binding, 0008641=small protein activating enzyme activity, 0004839=ubiquitin activating enzyme activity" "0051092=positive regulation of NF-kappaB transcription factor activity, 0019950=SMT3-dependent protein catabolic process, 0006959=humoral immune response, 0016925=protein sumoylation" "0005737=cytoplasm, 0005634=nucleus, 0031510=SUMO activating enzyme complex" "UBA2, dUba2, Sae2, Dmuba2, uba2, sip2, DmSAE2, Smt3-activating enzyme 2, L36, SAE2, Smt3 activating enzyme 2, Ubc2, ubiquitin-activating enzyme (E1), DmUba2, DmSae2, CG7528" "IPR016040=NAD(P)-binding domain, IPR018074=Ubiquitin-activating enzyme, E1, active site, IPR028077=Ubiquitin/SUMO-activating enzyme ubiquitin-like domain, IPR000594=THIF-type NAD/FAD binding fold, IPR030661=SUMO-activating enzyme subunit SAE2/Uba2, IPR019572=Ubiquitin-activating enzyme, catalytic cysteine domain" CG7528 16-Dec-15 2015_12 ENSDARG00000051883 YDR390C(UBA2) WBGene00006700(uba-2) ENSXETG00000002374(TEgg032e11.1) ENSMUSG00000052997(Uba2) ENSG00000126261(UBA2) " adult stage , embryonic stage | stage 6-15 , embryonic stage | embryonic cycle 10-14 " " germarium

, organism

,

, oocyte

" "increased cell death,somatic clone,cell lethal,decreased cell number,lethal - all die before end of P-stage,recessive,some die during P-stage,lethal,female fertile,visible,temperature conditional,immune response defective,tumorigenic" "imaginal disc,optic lobe,wing disc,somatic clone,eye,ommatidium,pigment cell,temperature conditional,embryonic/larval fat body,embryonic/larval hemocoel,eye disc,adult head" FBgn0033224 Nop17l Nop17 like http://flybase.net/reports/FBgn0033224.html protein_coding_gene 0008157=protein phosphatase 1 binding "CG1553, NOP17 like" IPR012981=PIH1 family CG1553 16-Dec-15 2015_12 ENSXETG00000009122(C14orf104) ENSMUSG00000020973(1110034A24Rik) ENSG00000165506(DNAAF2) viable "wing,posterior wing margin" FBgn0263802 CR43605 http://flybase.net/reports/FBgn0263802.html "FBgn0263580, FBgn0263614" non_protein_coding_gene CR43623 CR43605 16-Dec-15 2015_12 FBgn0262119 l(2)NC195 http://flybase.net/reports/FBgn0262119.html gene 16-Dec-15 2015_12 FBgn0023469 anon-50CDa anon-50CDa http://flybase.net/reports/FBgn0023469.html gene unnamed 16-Dec-15 2015_12 FBgn0036402 CG6650 http://flybase.net/reports/FBgn0036402.html "FBgn0026212, FBgn0046470, FBgn0046471, FBgn0046472" protein_coding_gene "0016773=phosphotransferase activity, alcohol group as acceptor" 0005975=carbohydrate metabolic process "anon-WO0172774.122, l(3)067006, anon-WO0172774.121, anon-WO0172774.123, 0670/06, l(3)S067006" "IPR007666=ADP-specific phosphofructokinase/glucokinase, IPR029056=Ribokinase-like" CG6650 16-Dec-15 2015_12 ENSDARG00000062785(adpgk2) WBGene00016810(C50D2.7) ENSXETG00000022910(ADPGK) ENSMUSG00000025236(Adpgk) ENSG00000159322(ADPGK) "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,viable" FBgn0032781 CG9987 http://flybase.net/reports/FBgn0032781.html protein_coding_gene 0003972=RNA ligase (ATP) activity "0006388=tRNA splicing, via endonucleolytic cleavage and ligation, 0022008=neurogenesis" 0072669=tRNA-splicing ligase complex "IPR027513=tRNA-splicing ligase RtcB homologue, eukaryotic, IPR001233=tRNA-splicing ligase, RtcB" CG9987 16-Dec-15 2015_12 ENSDARG00000059107(zgc:76871) WBGene00008877(F16A11.2) ENSXETG00000011523(Q561P3_XENTR) ENSMUSG00000001783(D10Wsu52e) ENSG00000100220(C22orf28) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "trichogen cell,mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0000351 cort cortex http://flybase.net/reports/FBgn0000351.html FBgn0031847 protein_coding_gene 0010997=anaphase-promoting complex binding "0007343=egg activation, 0007143=female meiotic division, 0007349=cellularization, 0007147=female meiosis II, 0051487=activation of anaphase-promoting complex activity involved in meiotic cell cycle, 0007279=pole cell formation, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation, 0051297=centrosome organization, 0007144=female meiosis I, 0045143=homologous chromosome segregation" "0005813=centrosome, 0005737=cytoplasm" "Cortex, Cort, CG11330, cor, cdc20-like" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG11330 16-Dec-15 2015_12 "wild-type,female sterile,recessive,meiotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female,visible,partially lethal - majority die,some die during pupal stage" "pole cell,maternal effect,wing,posterior compartment,mesothoracic tergum" FBgn0014898 anon-10Ae anon-10Ae http://flybase.net/reports/FBgn0014898.html gene unnamed 16-Dec-15 2015_12 FBgn0265581 CR44408 http://flybase.net/reports/FBgn0265581.html non_protein_coding_gene CR44408 16-Dec-15 2015_12 FBgn0063411 l(3)3450-L lethal (3) 3450-L http://flybase.net/reports/FBgn0063411.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0036910 Cyp305a1 Cyp305a1 http://flybase.net/reports/FBgn0036910.html protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CYP305A1-Dm, 305a1, Cyp305A1, Cytochrome P450 305a1, cytochrome P450, AAF49108.1, CG8733" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG8733 16-Dec-15 2015_12 FBgn0002659 fs(2)51Fb female sterile (2) 51Fb http://flybase.net/reports/FBgn0002659.html gene 0007349=cellularization "mat(2)cell-H, mat(2)cellQL46" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0038220 CG12207 http://flybase.net/reports/FBgn0038220.html protein_coding_gene IPR018392=LysM domain CG12207 16-Dec-15 2015_12 ENSMUSG00000053769(Lysmd1) ENSG00000163155(LYSMD1) viable FBgn0267233 CR45673 http://flybase.net/reports/FBgn0267233.html non_protein_coding_gene CR45673 16-Dec-15 2015_12 FBgn0263025 CG43320 http://flybase.net/reports/FBgn0263025.html FBgn0039540 protein_coding_gene CG12879 "IPR003347=JmjC domain, IPR013296=HSPB1-associated protein 1" CG43320 16-Dec-15 2015_12 viable FBgn0029919 CG14432 http://flybase.net/reports/FBgn0029919.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065364 l(2)SH1724 lethal (2) SH1724 http://flybase.net/reports/FBgn0065364.html gene l(2)SH2 1724 16-Dec-15 2015_12 "lethal,recessive" FBgn0053919 CG33919 http://flybase.net/reports/FBgn0053919.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33919 16-Dec-15 2015_12 FBgn0083152 S(smoDN)194 Suppressor of smoDN 194 http://flybase.net/reports/FBgn0083152.html gene 16-Dec-15 2015_12 FBgn0060707 l(3)S070503b lethal (3) S070503b http://flybase.net/reports/FBgn0060707.html gene 0705/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0044097 E(rst)D151 E(rst)D151 http://flybase.net/reports/FBgn0044097.html gene 0001745=compound eye morphogenesis D151 16-Dec-15 2015_12 viable FBgn0028989 shrv shrinking violet http://flybase.net/reports/FBgn0028989.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 dendrite | dorsal | embryonic stage FBgn0082680 E(ftz)4038 E(ftz)4038 http://flybase.net/reports/FBgn0082680.html gene 4038 16-Dec-15 2015_12 FBgn0042647 elav::Rbp9 elav::Rbp9 http://flybase.net/reports/FBgn0042647.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0036510 CG7427 http://flybase.net/reports/FBgn0036510.html protein_coding_gene 0043130=ubiquitin binding 0045116=protein neddylation "0005634=nucleus, 0005737=cytoplasm" "IPR014764=Defective-in-cullin neddylation protein, IPR009060=UBA-like, IPR005176=Potentiating neddylation domain" CG7427 16-Dec-15 2015_12 "ENSDARG00000040838(LOC100333691),ENSDARG00000041592(dcun1d2)" YLR128W(DCN1) WBGene00010428(dcn-1) ENSXETG00000016813(rp42) "ENSMUSG00000027708(Dcun1d1),ENSMUSG00000074910,ENSMUSG00000038506(Dcun1d2)" "ENSG00000043093(DCUN1D1),ENSG00000150401(DCUN1D2)" viable FBgn0000384 cta concertina http://flybase.net/reports/FBgn0000384.html "FBan0017678, FBgn0058010" protein_coding_gene "0019001=guanyl nucleotide binding, 0003924=GTPase activity, 0031683=G-protein beta/gamma-subunit complex binding, 0031752=D5 dopamine receptor binding, 0005525=GTP binding, 0004871=signal transducer activity" "0010004=gastrulation involving germ band extension, 0070252=actin-mediated cell contraction, 0016476=regulation of embryonic cell shape, 0007186=G-protein coupled receptor signaling pathway, 0007266=Rho protein signal transduction, 0007374=posterior midgut invagination, 0007166=cell surface receptor signaling pathway, 0008360=regulation of cell shape, 0007370=ventral furrow formation, 0007369=gastrulation, 0003384=apical constriction involved in gastrulation, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway" "0031526=brush border membrane, 0005834=heterotrimeric G-protein complex, 0031234=extrinsic component of cytoplasmic side of plasma membrane" "Cta, Galpha[[12/13]] subunit, mat(2)fog, CG17678, mat(2)cta, Concertina, CG40010, conc" "IPR000469=G-protein alpha subunit, group 12, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011025=G protein alpha subunit, helical insertion" CG17678 16-Dec-15 2015_12 "ENSDARG00000037924(gna13b),ENSDARG00000025826(gna12)" WBGene00001674(gpa-12) ENSXETG00000001253(GNA13) "ENSMUSG00000020611(Gna13),ENSMUSG00000000149(Gna12)" "ENSG00000120063(GNA13),ENSG00000146535(GNA12)" " adult stage && oogenesis stage , embryonic stage " " nurse cell

, oocyte

, mesoderm

" "female sterile,wild-type,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,neuroanatomy defective,cell shape defective,partially lethal,lethal" "embryo,lateral,ventral furrow,amnioproctodeal invagination,embryonic/first instar larval cuticle,maternal effect,posterior endoderm,posterior midgut primordium,extended germ band embryo,cephalopharyngeal skeleton,egg chamber,nurse cell ring canal,embryonic epidermis,ventral,gonad,segmental nerve branch SNa of A1-7,anterior,posterior,embryo | embryonic stage 6" FBgn0267463 CR45813 http://flybase.net/reports/FBgn0267463.html non_protein_coding_gene CR45813 16-Dec-15 2015_12 FBgn0259447 EP-M68 http://flybase.net/reports/FBgn0259447.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0002433 l(3)KE142 lethal (3) KE142 http://flybase.net/reports/FBgn0002433.html gene 16-Dec-15 2015_12 lethal FBgn0033313 Cirl Calcium-independent receptor for ë±-latrotoxin http://flybase.net/reports/FBgn0033313.html "FBgn0046507, FBgn0046515, FBgn0047319" protein_coding_gene "0016524=latrotoxin receptor activity, 0030246=carbohydrate binding" "0007186=G-protein coupled receptor signaling pathway, 0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0007166=cell surface receptor signaling pathway" "0016020=membrane, 0008021=synaptic vesicle, 0016021=integral component of membrane" "BcDNA:GH07331, Cirl, anon-WO0170980.8, dcirl, anon-WO0170980.7, CIRL, CG8639" "IPR017981=GPCR, family 2-like, IPR000203=GPS motif, IPR000922=D-galactoside/L-rhamnose binding SUEL lectin domain" CG8639 16-Dec-15 2015_12 "ENSDARG00000061121(si:ch211-209p5.2),ENSDARG00000018436" WBGene00002251(lat-1) ENSXETG00000022840(LPHN1) "ENSMUSG00000037605(Lphn3),ENSMUSG00000028184(Lphn2),ENSMUSG00000013033(Lphn1)" "ENSG00000150471(LPHN3),ENSG00000117114(LPHN2),ENSG00000072071(LPHN1)" "viable,fertile,lethal,partially lethal - majority die" FBgn0014926 anon-72ABj anon-72ABj http://flybase.net/reports/FBgn0014926.html gene 16-Dec-15 2015_12 FBgn0011937 tRNA:N5:42Ag transfer RNA:asn5:42Ag http://flybase.net/reports/FBgn0011937.html "FBgn0003759, FBgn0053972, FBgn0060129" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033442=AAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "Asn-tRNA-7, AE002769.trna11-AsnGTT, CR33972, Asn7, tRNA:asn5:42Ag, tRNA:N:GTT:AE002769-e, chr2R.trna2-AsnGTT" CR33972 16-Dec-15 2015_12 FBgn0058399 CG40399 http://flybase.net/reports/FBgn0058399.html protein_coding_gene 16-Dec-15 2015_12 DRSC22499 IE 2.82014913 -0.064975835 1.152973532 1.549008817 0.199241673 0.293157751 FBgn0260634 eIF4G2 eukaryotic translation initiation factor 4G2 http://flybase.net/reports/FBgn0260634.html "FBgn0039122, FBgn0002841" protein_coding_gene "0000340=RNA 7-methylguanosine cap binding, 0003743=translation initiation factor activity" "0048102=autophagic cell death, 0048515=spermatid differentiation, 0007283=spermatogenesis, 0006413=translational initiation, 0048136=male germ-line cyst formation, 0008315=meiotic G2/MI transition, 0035071=salivary gland cell autophagic cell death, 0007140=male meiosis, 0048137=spermatocyte division, 0000082=G1/S transition of mitotic cell cycle" 0016281=eukaryotic translation initiation factor 4F complex "ofs, eIF-4G-like protein, eIF4G-2, male sterile (3) nc32, nc32, CG10192, ms(3)nc32, off-schedule" "IPR016021=MIF4G-like domain, IPR003891=Initiation factor eIF-4 gamma, MA3, IPR016024=Armadillo-type fold, IPR003890=MIF4G-like, type 3" CG10192 16-Dec-15 2015_12 WBGene00002066(ifg-1) FBgn0030798 CG13003 http://flybase.net/reports/FBgn0030798.html protein_coding_gene CG13003 16-Dec-15 2015_12 "viable,fertile" FBgn0027570 Nep2 Neprilysin 2 http://flybase.net/reports/FBgn0027570.html protein_coding_gene "0004175=endopeptidase activity, 0008237=metallopeptidase activity, 0004222=metalloendopeptidase activity" 0006508=proteolysis "0005886=plasma membrane, 0005615=extracellular space" "NEP2, dNEP2, neprilysin-2, CG9761, DmNEP2, BcDNA:GH07643, neprilysin 2, nep2" "IPR008753=Peptidase M13, N-terminal domain, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13" CG9761 16-Dec-15 2015_12 viable FBgn0017395 l(1)10Br lethal (1) 10Br http://flybase.net/reports/FBgn0017395.html gene HM12 16-Dec-15 2015_12 "lethal,recessive" FBgn0039112 SdhD "Succinate dehydrogenase, subunit D" http://flybase.net/reports/FBgn0039112.html FBgn0046279 protein_coding_gene "0008177=succinate dehydrogenase (ubiquinone) activity, 0020037=heme binding, 0000104=succinate dehydrogenase activity, 0048039=ubiquinone binding" 0006099=tricarboxylic acid cycle "0016021=integral component of membrane, 0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), 0005743=mitochondrial inner membrane" "succinate dehydrogenase [ubiquinone] cytochrome B small subunit, Succinate dehydrogenase Cytochrome B small subunit, Succinate dehydrogenase Cytochrome b small subunit, CG10219, BEST:GH27735, DHSD, SUCCINATE DEHYDROGENASE (UBIQUINONE) CYTOCHROME B SMALL SUBUNIT" "IPR007992=Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS" CG10219 16-Dec-15 2015_12 "ENSDARG00000030139(sdhda),ENSDARG00000055712(sdhdb)" "YLR164W(),YDR178W(SDH4),YOR297C(TIM18)" WBGene00009353(sdhd-1) ENSXETG00000027683(TNeu097k19.1) ENSMUSG00000000171(Sdhd) ENSG00000204370(SDHD) viable FBgn0261501 CG42649 http://flybase.net/reports/FBgn0261501.html protein_coding_gene CG42649 16-Dec-15 2015_12 FBgn0000612 exi exigous http://flybase.net/reports/FBgn0000612.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male fertile,good,female fertile,reduced,male,female,body color defective" "adult thorax,adult abdomen" FBgn0266389 CR45029 http://flybase.net/reports/FBgn0266389.html non_protein_coding_gene CR45029 16-Dec-15 2015_12 FBgn0250786 Chd1 Chromodomain-helicase-DNA-binding protein 1 http://flybase.net/reports/FBgn0250786.html "FBgn0016132, FBgn0040118" protein_coding_gene "0004386=helicase activity, 0003682=chromatin binding, 0003676=nucleic acid binding, 0005524=ATP binding, 0008026=ATP-dependent helicase activity" "0048477=oogenesis, 0043486=histone exchange, 0035042=fertilization, exchange of chromosomal proteins, 0007476=imaginal disc-derived wing morphogenesis" "0005705=polytene chromosome interband, 0005703=polytene chromosome puff" "DmCHD1, chromo-ATPase/helicase-DNA-binding domain, dCHD1, lethal (2) 23Cd, CHD-1, l(2)23Cd, chd1, chromo-ATPase/helicase-DNA-binding protein 1, Chromodomain-helicase-DNA-binding protein, CG3733, CHD1,2, CHD1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR000953=Chromo/chromo shadow domain, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR016197=Chromo domain-like, IPR000330=SNF2-related, N-terminal domain, IPR001650=Helicase, C-terminal, IPR023779=Chromo domain, conserved site, IPR023780=Chromo domain, IPR025260=Domain of unknown function DUF4208" CG3733 16-Dec-15 2015_12 "ENSDARG00000060687,ENSDARG00000014878(zgc:173506)" YER164W(CHD1) WBGene00010369(H06O01.2) ENSXETG00000024129(CHD2) ENSMUSG00000023852(Chd1) "ENSG00000173575(CHD2),ENSG00000153922(CHD1)" embryonic stage&&adult stage FBgn0267067 CR45511 http://flybase.net/reports/FBgn0267067.html non_protein_coding_gene CR45511 16-Dec-15 2015_12 FBgn0260072 2L2526 http://flybase.net/reports/FBgn0260072.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0000103 aperB abnormal proboscis extension reflex B http://flybase.net/reports/FBgn0000103.html gene 0007637=proboscis extension reflex 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive,heat sensitive" FBgn0052407 CG32407 http://flybase.net/reports/FBgn0052407.html "FBgn0035650, FBgn0061442" protein_coding_gene "BcDNA:AT29938, CG10727" "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain" CG32407 16-Dec-15 2015_12 viable FBgn0031305 Iris Iris http://flybase.net/reports/FBgn0031305.html protein_coding_gene 0048477=oogenesis "Dm-cF, CG4715-env, CG4715" "IPR022058=Protein of unknown function DUF3610, IPR022048=Protein of unknown function DUF3609" CG4715 16-Dec-15 2015_12 "viable,fertile" FBgn0001244 hypoE hypoactive E http://flybase.net/reports/FBgn0001244.html gene 16-Dec-15 2015_12 "jumping defective,hypoactive,locomotor behavior defective" FBgn0010172 spno supernova http://flybase.net/reports/FBgn0010172.html gene "0007293=germarium-derived egg chamber formation, 0007276=gamete generation, 0007283=spermatogenesis, 0040016=embryonic cleavage" fs(3)2-210 16-Dec-15 2015_12 "mitotic cell cycle defective,non-rescuable maternal effect,recessive,maternal effect,lethal" "egg chamber,nurse cell,spermatocyte,spermatid" FBgn0263415 CR43461 http://flybase.net/reports/FBgn0263415.html non_protein_coding_gene CR43461 16-Dec-15 2015_12 FBgn0030007 ë±-PheRS Phenylalanyl-tRNA synthetase ë± subunit http://flybase.net/reports/FBgn0030007.html protein_coding_gene "0002161=aminoacyl-tRNA editing activity, 0000049=tRNA binding, 0004826=phenylalanine-tRNA ligase activity, 0005524=ATP binding" 0006432=phenylalanyl-tRNA aminoacylation "0005737=cytoplasm, 0009328=phenylalanine-tRNA ligase complex" CG2263 "IPR004529=Phenylalanyl-tRNA synthetase, class IIc, alpha subunit, IPR002319=Phenylalanyl-tRNA synthetase, IPR006195=Aminoacyl-tRNA synthetase, class II" CG2263 16-Dec-15 2015_12 ENSDARG00000032750 YFL022C(FRS2) WBGene00001497(fars-1) ENSXETG00000007936(FARSA) ENSMUSG00000003808(Farsa) ENSG00000179115(FARSA) lethal DRSC18224 I -0.688842262 1.51901377 -0.109299547 0.796783395 0.681994899 -0.599387696 FBgn0065436 l(2)SH1470 lethal (2) SH1470 http://flybase.net/reports/FBgn0065436.html gene l(2)SH2 1470 16-Dec-15 2015_12 "lethal,recessive" FBgn0020354 anon-2G8 anon-2G8 http://flybase.net/reports/FBgn0020354.html gene "2G8, unnamed" 16-Dec-15 2015_12 FBgn0025011 E(dpp)55A E(dpp)55A http://flybase.net/reports/FBgn0025011.html gene 16-Dec-15 2015_12 FBgn0039170 CG13609 http://flybase.net/reports/FBgn0039170.html protein_coding_gene "IPR021394=Mediator complex, subunit Med25, PTOV activation and synapsin 2" CG13609 16-Dec-15 2015_12 ENSMUSG00000038502(Ptov1) ENSG00000104960(PTOV1) viable FBgn0037999 CG4860 http://flybase.net/reports/FBgn0037999.html protein_coding_gene "0003995=acyl-CoA dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" 0006635=fatty acid beta-oxidation Dmel\CG4860 "IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006089=Acyl-CoA dehydrogenase, conserved site, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal" CG4860 16-Dec-15 2015_12 ENSDARG00000030781(acads) viable FBgn0036502 CG7841 http://flybase.net/reports/FBgn0036502.html protein_coding_gene IPR029428=FAM195 CG7841 16-Dec-15 2015_12 ENSDARG00000061256(si:dkey-44g23.5) ENSXETG00000020259(TNeu015l01.1) ENSMUSG00000025732(Fam195a) ENSG00000172366(FAM195A) FBgn0026626 pel perle http://flybase.net/reports/FBgn0026626.html gene 0007417=central nervous system development 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,commissure,midline glial cell,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0000297 Cg19-20 Cg19-20 http://flybase.net/reports/FBgn0000297.html FBgn0000298 gene 0005587=collagen type IV trimer "Cg19EF, Collagen 19EF, Cg20AB, DCg2, Collagen 20AB" 16-Dec-15 2015_12 FBgn0051849 CG31849 http://flybase.net/reports/FBgn0051849.html FBgn0047198 protein_coding_gene "0003830=beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity" 0006487=protein N-linked glycosylation 0016020=membrane "dMGAT3, BcDNA:LD34806" "IPR006813=Glycosyl transferase, family 17" CG31849 16-Dec-15 2015_12 "ENSDARG00000036619,ENSDARG00000038069(mgat3)" ENSXETG00000016128(MGAT3) ENSMUSG00000042428(Mgat3) ENSG00000128268(MGAT3) "viable,body color defective" mesothoracic tergum FBgn0069118 mus212 mutagen-sensitive 212 http://flybase.net/reports/FBgn0069118.html gene 16-Dec-15 2015_12 "viable,chemical sensitive,female sterile,recessive" FBgn0262521 l(3)psg3 lethal (3) persistent salivary gland 3 http://flybase.net/reports/FBgn0262521.html gene 0043067=regulation of programmed cell death psg3 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during P-stage" embryonic/larval salivary gland FBgn0039467 CG14253 http://flybase.net/reports/FBgn0039467.html protein_coding_gene CG14253 16-Dec-15 2015_12 viable FBgn0260372 GSd485 http://flybase.net/reports/FBgn0260372.html gene 16-Dec-15 2015_12 lethal FBgn0086037 snoRNA:Me28S-A2958 http://flybase.net/reports/FBgn0086037.html snoRNA_gene "CR34666, Me28S-Am2958" CR34666 16-Dec-15 2015_12 FBgn0046663 anon-38C.36 anon-38C.36 http://flybase.net/reports/FBgn0046663.html gene 38C.36 16-Dec-15 2015_12 FBgn0036509 CG7739 http://flybase.net/reports/FBgn0036509.html protein_coding_gene IPR024881=T-cell immunomodulatory protein CG7739 16-Dec-15 2015_12 WBGene00014023(tag-256) ENSMUSG00000031703(Itfg1) ENSG00000129636(ITFG1) "viable,fertile" FBgn0028244 l(3)S000625a lethal (3) S000625a http://flybase.net/reports/FBgn0028244.html gene "0006/25, l(3)S000625" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262788 CG43169 http://flybase.net/reports/FBgn0262788.html protein_coding_gene MB8.chr3L.pasa.50 CG43169 16-Dec-15 2015_12 FBgn0028397 Tob Tob http://flybase.net/reports/FBgn0028397.html protein_coding_gene 0008285=negative regulation of cell proliferation "Transducer of ERBB2, CG9214" "IPR015676=Tob, IPR002087=Anti-proliferative protein" CG9214 16-Dec-15 2015_12 ENSXETG00000011060(tob1) "ENSMUSG00000037573(Tob1),ENSMUSG00000048546(Tob2)" "ENSG00000141232,ENSG00000183864(TOB2)" "lethal,recessive,viable" embryonic/larval hemocyte | third instar larval stage FBgn0266038 CR44803 http://flybase.net/reports/FBgn0266038.html non_protein_coding_gene lincRNA.223 CR44803 16-Dec-15 2015_12 FBgn0264823 CR44031 http://flybase.net/reports/FBgn0264823.html non_protein_coding_gene CR44031 16-Dec-15 2015_12 FBgn0066352 l(3)99DEc lethal (3) 99DEc http://flybase.net/reports/FBgn0066352.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005671 Vha55 Vacuolar H+-ATPase 55kD subunit http://flybase.net/reports/FBgn0005671.html "FBgn0002345, FBgn0011789" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0005524=ATP binding" "0046034=ATP metabolic process, 0015991=ATP hydrolysis coupled proton transport, 0015992=proton transport, 0007035=vacuolar acidification" "0005829=cytosol, 0005903=brush border, 0048471=perinuclear region of cytoplasm, 0005769=early endosome, 0033181=plasma membrane proton-transporting V-type ATPase complex, 0005886=plasma membrane, 0000221=vacuolar proton-transporting V-type ATPase, V1 domain" "V-ATPase, l(3)SzA, B subunit, vha55, Vacuolar H[+]-ATPase 55-kDa B subunit, V1 B subunit, ATP6V1B1, V-ATPase B-subunit, 1208/13, vacuolar ATPase B subunit, l(3)87Ca, vacuolar ATP synthase subunit B, l(3)j2E9, Vacuolar H[+]-ATPase 55kD B subunit, Vacuolar H+ATPase subunit B, VAT-2, B subunit of V-ATPase, V-ATPase subunit B, CG17369, Vacuolar H+-ATPase 55kD B subunit, SzA" "IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005723=ATPase, V1 complex, subunit B, IPR022879=V-type ATP synthase regulatory subunit B/beta, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal" CG17369 16-Dec-15 2015_12 "ENSDARG00000043465(LOC100332756),ENSDARG00000013443(atp6v1ba)" YBR127C(VMA2) WBGene00006921(vha-12) "ENSXETG00000016476(ATP6V1B2),ENSXETG00000021532(ATP6V1B1)" ENSMUSG00000006273(Atp6v1b2) ENSG00000147416(ATP6V1B2) "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,size defective,decreased cell number,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "Malpighian tubule,eye disc,somatic clone,multivesicular body | larval stage | somatic clone" FBgn0023152 Su(mg)2-7 Suppressor of modifier of gypsy 2-7 http://flybase.net/reports/FBgn0023152.html gene 16-Dec-15 2015_12 FBgn0000551 Edg78E Ecdysone-dependent gene 78E http://flybase.net/reports/FBgn0000551.html "FBtr0078408, FBpp0078062" protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008011=structural constituent of pupal chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "EDG-78, DmelEdg78E, Edg78, CG7673, EDG78, DMLCP78, Edg78e, EDG78E" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG7673 16-Dec-15 2015_12 prepupal stage epidermis

viable FBgn0016950 tilG touch insensitive larva G http://flybase.net/reports/FBgn0016950.html gene line 376 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0002674 mat(2)syn-B maternal effect syncytial blastoderm arrest B http://flybase.net/reports/FBgn0002674.html gene "0007279=pole cell formation, 0007349=cellularization" "mat(2)synHi10, syn-Hi10" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0030455 CG4318 http://flybase.net/reports/FBgn0030455.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG4318 16-Dec-15 2015_12 "ENSMUSG00000073209(Klf14),ENSMUSG00000035397(Klf16),ENSMUSG00000052040(Klf13),ENSMUSG00000033863(Klf9)" viable FBgn0250908 beat-VII beat-VII http://flybase.net/reports/FBgn0250908.html "FBgn0039447, FBgn0039445" protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "CG14248, CG42242, CG14249, Beat-VII, beat VII" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain" CG42242 16-Dec-15 2015_12 FBgn0015253 M(2)105 M(2)105 http://flybase.net/reports/FBgn0015253.html gene 16-Dec-15 2015_12 "visible,dominant,Minute" FBgn0051612 CG31612 http://flybase.net/reports/FBgn0051612.html "FBgn0032962, FBgn0032963" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" 0046331=lateral inhibition "0005634=nucleus, 0005811=lipid particle" "CG11632, CG11631" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG31612 16-Dec-15 2015_12 "viable,visible" chaeta DRSC03697 K -0.711753797 0.715122099 -0.65856561 0.284256276 -1.435859788 1.553365809 FBgn0266973 CR45424 http://flybase.net/reports/FBgn0266973.html non_protein_coding_gene CR45424 16-Dec-15 2015_12 FBgn0266225 CR44920 http://flybase.net/reports/FBgn0266225.html non_protein_coding_gene CR44920 16-Dec-15 2015_12 FBgn0035657 ë±Kap4 ë± Karyopherin-4 http://flybase.net/reports/FBgn0035657.html FBgn0035658 protein_coding_gene 0008320=protein transmembrane transporter activity "0043248=proteasome assembly, 0006606=protein import into nucleus" "0005643=nuclear pore, 0005737=cytoplasm" "Importin alpha4, alphaKap4, CG10478, CG11040, g7295403" "IPR016024=Armadillo-type fold, IPR019538=26S proteasome non-ATPase regulatory subunit 5, IPR024931=Importin subunit alpha, IPR011989=Armadillo-like helical, IPR000225=Armadillo" CG10478 16-Dec-15 2015_12 viable FBgn0030158 CG9686 http://flybase.net/reports/FBgn0030158.html "FBgn0027688, FBgn0062901" protein_coding_gene "BcDNA:RH74092, anon-EST:Posey3, CT6802" CG9686 16-Dec-15 2015_12 viable DRSC18439 E 1.032549265 -0.838006684 1.777192874 -0.943145617 -0.345358448 0.537755849 FBgn0264437 CR43855 http://flybase.net/reports/FBgn0264437.html non_protein_coding_gene CR43855 16-Dec-15 2015_12 FBgn0261588 pdm3 pou domain motif 3 http://flybase.net/reports/FBgn0261588.html "FBgn0033288, FBgn0063323, FBgn0033282" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007411=axon guidance, 0006355=regulation of transcription, DNA-templated, 0007409=axonogenesis, 0007608=sensory perception of smell, 0007412=axon target recognition" 0005634=nucleus "Pdm3, CG42698, BcDNA:AT16994, POU domain motif 3, CG11641, CG14755" "IPR009057=Homeodomain-like, IPR001356=Homeobox domain, IPR010982=Lambda repressor-like, DNA-binding domain, IPR000327=POU-specific domain, IPR013847=POU domain" CG42698 16-Dec-15 2015_12 "ENSDARG00000044774(pou5f1),ENSDARG00000026918,ENSDARG00000042032(pou3f3a),ENSDARG00000009823(pou3f1),ENSDARG00000052387(LOC553427)" "ENSXETG00000014200(),ENSXETG00000005600(POU6F2)" "ENSMUSG00000009739(Pou6f1),ENSMUSG00000009734(Pou6f2)" FBgn0027983 l(3)S134303 lethal (3) S134303 http://flybase.net/reports/FBgn0027983.html gene 1343/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0027179 l(2)60A-O lethal (2) 60A-O http://flybase.net/reports/FBgn0027179.html gene 16-Dec-15 2015_12 lethal FBgn0016894 l(3)64Cd lethal (3) 64Cd http://flybase.net/reports/FBgn0016894.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060713 l(3)S070106b lethal (3) S070106b http://flybase.net/reports/FBgn0060713.html gene 0701/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033733 CG8834 http://flybase.net/reports/FBgn0033733.html protein_coding_gene 0016207=4-coumarate-CoA ligase activity 0008152=metabolic process mdcds_23070 "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG8834 16-Dec-15 2015_12 viable FBgn0035453 CG10357 http://flybase.net/reports/FBgn0035453.html protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" 0016042=lipid catabolic process "IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family" CG10357 16-Dec-15 2015_12 viable FBgn0000191 bkl buckledlike http://flybase.net/reports/FBgn0000191.html gene bucklelike 16-Dec-15 2015_12 "visible,recessive,viable,fertile" "wing,wing vein,eye" FBgn0035452 CG10359 http://flybase.net/reports/FBgn0035452.html protein_coding_gene "Fibrinogen-related protein, Fibronogen-like, AAF47782, FBpp0072995" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain" CG10359 16-Dec-15 2015_12 "WBGene00016769(C49C8.5),WBGene00012782(Y43C5A.2)" viable FBgn0039961 CG17679 http://flybase.net/reports/FBgn0039961.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014326 l(3)ry6 lethal (3) ry6 http://flybase.net/reports/FBgn0014326.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0037299 Vps37B Vacuolar protein sorting 37B http://flybase.net/reports/FBgn0037299.html protein_coding_gene 0032509=endosome transport via multivesicular body sorting pathway 0000813=ESCRT I complex "DmVPS37, CG1115, Vps37, vps37B" "IPR009851=Modifier of rudimentary, Modr" CG1115 16-Dec-15 2015_12 "ENSDARG00000039319(si:dkey-21k4.4),ENSDARG00000028391(zgc:114173),ENSDARG00000031836(zgc:153996)" WBGene00016990(vps-37) ENSXETG00000005797(BC061362.1) "ENSMUSG00000066278(Vps37b),ENSMUSG00000048832(Vps37c),ENSMUSG00000043614(Vps37d)" "ENSG00000139722(VPS37B),ENSG00000167987(VPS37C)" "viable,fertile" FBgn0052173 tRNA:CR32173 transfer RNA:CR32173 http://flybase.net/reports/FBgn0052173.html FBgn0060117 tRNA_gene 0033424=CCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna35-ProCGG, AE002602.trna1-ProCGG, tRNA:P:CGG:AE002602-a, CR32173" CR32173 16-Dec-15 2015_12 "viable,fertile" FBgn0052182 CG32182 http://flybase.net/reports/FBgn0052182.html protein_coding_gene CG32182 16-Dec-15 2015_12 viable FBgn0083247 EB3 EB3 http://flybase.net/reports/FBgn0083247.html gene 16-Dec-15 2015_12 FBgn0028113 l(3)S065103 lethal (3) S065103 http://flybase.net/reports/FBgn0028113.html gene 0651/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0002315 l(3)85Af lethal (3) 85Af http://flybase.net/reports/FBgn0002315.html gene L6 16-Dec-15 2015_12 lethal FBgn0065522 l(2)SH1125 lethal (2) SH1125 http://flybase.net/reports/FBgn0065522.html gene l(2)SH2 1125 16-Dec-15 2015_12 "lethal,recessive" FBgn0020607 anon-12Dc anon-12Dc http://flybase.net/reports/FBgn0020607.html gene D2 16-Dec-15 2015_12 FBgn0020765 Acp65Aa Adult cuticle protein 65Aa http://flybase.net/reports/FBgn0020765.html FBgn0062922 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle, 0008012=structural constituent of adult chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Acp65Aa, BcDNA:RH61147, DMACP65A, DmelAcp65Aa, DCP5, CG10297, Acp65A, ACP65A" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG10297 16-Dec-15 2015_12 pupal stage | 50-80 hr viable FBgn0065936 l(2)SH0124 lethal (2) SH0124 http://flybase.net/reports/FBgn0065936.html gene l(2)SH2 0124 16-Dec-15 2015_12 "lethal,recessive" FBgn0084020 CG41458 http://flybase.net/reports/FBgn0084020.html FBan0041458 protein_coding_gene 16-Dec-15 2015_12 FBgn0039869 CG1890 http://flybase.net/reports/FBgn0039869.html protein_coding_gene "0051082=unfolded protein binding, 0015631=tubulin binding" 0007021=tubulin complex assembly IPR004226=Tubulin binding cofactor A CG1890 16-Dec-15 2015_12 ENSDARG00000016754(tbca) YOR265W(RBL2) WBGene00021475(Y39G10AR.20) ENSXETG00000016574(TBCA) ENSMUSG00000042043(Tbca) ENSG00000171530(TBCA) "viable,fertile" DRSC15395 I -0.449117659 -1.52719604 -0.093396222 0.047877916 -0.092281287 -0.163845916 FBgn0005474 l(1)ts996 lethal (1) ts996 http://flybase.net/reports/FBgn0005474.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0283430 CR46273 http://flybase.net/reports/FBgn0283430.html pseudogene_attribute CR46273 16-Dec-15 2015_12 FBgn0267420 CR45773 http://flybase.net/reports/FBgn0267420.html pseudogene_attribute CR45773 16-Dec-15 2015_12 FBgn0086347 Myo31DF Myosin 31DF http://flybase.net/reports/FBgn0086347.html "FBgn0011673, FBgn0064139" protein_coding_gene "0003779=actin binding, 0005524=ATP binding, 0042623=ATPase activity, coupled, 0003774=motor activity" "0048803=imaginal disc-derived male genitalia morphogenesis, 0007498=mesoderm development, 0071907=determination of digestive tract left/right asymmetry, 0007368=determination of left/right symmetry" "0005737=cytoplasm, 0016459=myosin complex, 0005938=cell cortex" "DmIA, souther, MYOIA, MyoID, Myo-IA, Myosin-IA, myo31DF, myosin-IA, Myosin31DF, Myo1A, DroMIA, Myosin ID, myosin1A, Myosin IA, myosin 1a, MyoIA, Dm IA, IA, myosin IA, Myo31DF, Myosin 31DF, myosin I, unconventional myosin 31DF, myoID, myosin ID, CG7438, Myosin 1D" "IPR010926=Unconventional myosin tail, actin- and lipid-binding, IPR001609=Myosin head, motor domain, IPR000048=IQ motif, EF-hand binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG7438 16-Dec-15 2015_12 "ENSDARG00000036863,ENSDARG00000036104(si:dkeyp-92c9.3)" "YKL129C(MYO3),YMR109W(MYO5)" WBGene00002038(hum-5) ENSXETG00000003194(MYO1D) "ENSMUSG00000035441(Myo1d),ENSMUSG00000020437(Myo1g)" "ENSG00000176658(MYO1D),ENSG00000136286(MYO1G)" embryonic stage -- adult stage " embryonic stage -- adult stage , embryonic stage | late " " embryonic/larval hindgut

, embryonic/larval proventriculus

, gastric caecum

, embryonic/larval digestive system

, embryonic/larval midgut

" FBgn0010504 kermit kermit http://flybase.net/reports/FBgn0010504.html "FBgn0026587, FBgn0033270" protein_coding_gene 0001965=G-protein alpha-subunit binding "0001736=establishment of planar polarity, 0031987=locomotion involved in locomotory behavior, 0008340=determination of adult lifespan, 0016055=Wnt signaling pathway, 0009966=regulation of signal transduction" 0031982=vesicle "dGIPC, lethal (2) 02045, l(2)02045, dKermit, CG11546, BEST:LD04728, Kermit, LD04728" "IPR017379=Uncharacterised conserved protein UCP038083, PDZ, IPR001478=PDZ domain" CG11546 16-Dec-15 2015_12 "ENSDARG00000053074(zgc:136839),ENSDARG00000009488(gipc2),ENSDARG00000010771(gipc1)" "WBGene00016440(C35D10.2),WBGene00009681(F44D12.4)" "ENSXETG00000013148(GIPC2),ENSXETG00000020602(GIPC1),ENSXETG00000022097(GIPC3)" "ENSMUSG00000019433(Gipc1),ENSMUSG00000039131(Gipc2),ENSMUSG00000034872(Gipc3)" "ENSG00000123159(GIPC1),ENSG00000179855(GIPC3),ENSG00000137960(GIPC2)" "planar polarity defective,visible,wild-type,locomotor behavior defective,short lived,heat stress response defective,lethal,recessive,partially lethal - majority die,viable,dominant" "wing hair,supernumerary,trichome,mesothoracic tergum,dopaminergic neuron,wing" FBgn0022982 retx retinal exchanger http://flybase.net/reports/FBgn0022982.html gene 0005432=calcium:sodium antiporter activity unnamed 16-Dec-15 2015_12 FBgn0027965 l(3)S145110 lethal (3) S145110 http://flybase.net/reports/FBgn0027965.html gene "l(3)s145110, 1451/10" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0028089 l(3)S083705 lethal (3) S083705 http://flybase.net/reports/FBgn0028089.html gene 0837/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0037174 CG14457 http://flybase.net/reports/FBgn0037174.html "FBgn0040641, FBgn0063095" protein_coding_gene 0005615=extracellular space "BcDNA:LP08817, CG18618" IPR010562=Haemolymph juvenile hormone binding CG14457 16-Dec-15 2015_12 viable FBgn0263763 CG43680 http://flybase.net/reports/FBgn0263763.html protein_coding_gene CG43680 16-Dec-15 2015_12 FBgn0032330 Samuel SAM-motif ubiquitously expressed punctatedly localized protein http://flybase.net/reports/FBgn0032330.html "FBgn0032332, FBgn0032333, FBgn0051868" protein_coding_gene "0040008=regulation of growth, 0007283=spermatogenesis, 0031935=regulation of chromatin silencing" 0005634=nucleus "mdcds_1002, CG14917, 78BP, middleman of seventy-eight signaling, Moses, moses, CG12291, CG14918, CG31868, Middleman of seventy-eight signaling" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG31868 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of P-stage,some die during P-stage,lethal,hyperplasia,developmental rate defective" "imaginal disc,embryonic/larval brain" FBgn0086042 snoRNA:Me28S-G980 http://flybase.net/reports/FBgn0086042.html snoRNA_gene "Me28S-Gm980, Me28S-G980, CR34671" CR34671 16-Dec-15 2015_12 FBgn0028057 l(3)S094204 lethal (3) S094204 http://flybase.net/reports/FBgn0028057.html gene 0942/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0084437 l(3)76BDj l(3)76BDj http://flybase.net/reports/FBgn0084437.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036688 Fit2 Fermitin 2 http://flybase.net/reports/FBgn0036688.html protein_coding_gene 0048738=cardiac muscle tissue development CG7729 "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749=Band 4.1 domain, IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG7729 16-Dec-15 2015_12 "ENSDARG00000052652(LOC100332544),ENSDARG00000020242(fermt2),ENSDARG00000030938(zgc:64101)" WBGene00006836(unc-112) "ENSXETG00000005517(FERMT1),ENSXETG00000027692(plekhc1)" "ENSMUSG00000037712(Fermt2),ENSMUSG00000027356(Fermt1),ENSMUSG00000024965(Fermt3)" "ENSG00000073712(FERMT2),ENSG00000101311(FERMT1),ENSG00000149781(FERMT3)" "viable,fertile" FBgn0039156 CG6178 http://flybase.net/reports/FBgn0039156.html protein_coding_gene "0004467=long-chain fatty acid-CoA ligase activity, 0045289=luciferin monooxygenase activity, 0004321=fatty-acyl-CoA synthase activity" "0006637=acyl-CoA metabolic process, 0046949=fatty-acyl-CoA biosynthetic process, 0001676=long-chain fatty acid metabolic process" 0005777=peroxisome "Fatty Acyl-CoA Synthetase, fatty acyl-CoA synthetase" "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG6178 16-Dec-15 2015_12 YBR222C(PCS60) "WBGene00008669(acs-14),WBGene00007082(acs-10),WBGene00022849(acs-6)" ENSXETG00000019194() "viable,fertile" FBgn0063498 GstE2 Glutathione S transferase E2 http://flybase.net/reports/FBgn0063498.html FBgn0034336 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "DmGSTE2, GSTE2, gste2, CG17523" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal" CG17523 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0037930 CG14715 http://flybase.net/reports/FBgn0037930.html "FBgn0061376, FBgn0062478" protein_coding_gene "0003755=peptidyl-prolyl cis-trans isomerase activity, 0005528=FK506 binding" "0018208=peptidyl-proline modification, 0006457=protein folding" "0016020=membrane, 0012505=endomembrane system" "BcDNA:RH50927, BcDNA:GM09283" "IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG14715 16-Dec-15 2015_12 ENSDARG00000044540(zgc:101826) YDR519W(FPR2) WBGene00001426(fkb-1) ENSMUSG00000056629(Fkbp2) ENSG00000173486(FKBP2) viable FBgn0039232 sosie sosie http://flybase.net/reports/FBgn0039232.html "FBgn0063686, FBgn0064906" protein_coding_gene "0007293=germarium-derived egg chamber formation, 0007297=ovarian follicle cell migration, 0007605=sensory perception of sound" "0035324=female germline ring canal, 0005886=plasma membrane, 0016324=apical plasma membrane" "CG13636, sie, BcDNA:RE20019, BcDNA:RE05274" CG13636 16-Dec-15 2015_12 "auditory perception defective,neurophysiology defective,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "egg chamber,nurse cell,female germline ring canal,follicle cell,dorsal appendage,maternal effect,mesothoracic tergum" FBgn0034095 CG15701 http://flybase.net/reports/FBgn0034095.html protein_coding_gene "IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG15701 16-Dec-15 2015_12 viable FBgn0038450 CG17560 http://flybase.net/reports/FBgn0038450.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity CT38785 "IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding, IPR016040=NAD(P)-binding domain" CG17560 16-Dec-15 2015_12 "viable,fertile" FBgn0264556 Gr39a Gustatory receptor 39a http://flybase.net/reports/FBgn0264556.html "FBgn0041244, FBgn0051622, FBgn0022191" protein_coding_gene 0008527=taste receptor activity "0008049=male courtship behavior, 0050909=sensory perception of taste" 0016021=integral component of membrane "Gr39aD, Gr39aB, 39D2a, 39D.2a, 39D.2, Gr39a.c, Gr39D2c, CG31622, Gr39D2d, GR39a, Gr39aA, gene Y, Gr39D2A, 39D.2b, 39D.2c, lethal (2) k05106, GR39D.2, Gr39D2a, Gr39a.b, Gustatory receptor 39D.2, l(2)k05106, Gr39a.a, 39D2c, Gr39a.d, Gr39D2b, 39D2b, 39D.2d, Gr39aC, 39D2d" IPR013604=7TM chemoreceptor CG31622 16-Dec-15 2015_12 FBgn0033278 CG14759 http://flybase.net/reports/FBgn0033278.html protein_coding_gene CG14759 16-Dec-15 2015_12 viable FBgn0025336 CG4882 http://flybase.net/reports/FBgn0025336.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity 0005634=nucleus "anon-60Aa, UD1, undefined 1, unnamed, LD24471, GM14313" "IPR019266=Ribosomal protein S27, mitochondrial" CG4882 16-Dec-15 2015_12 WBGene00010766(K11B4.1) "viable,visible" trichogen cell DRSC04495 E -0.901445819 0.116960056 -1.67581019 0.021247903 0.346273091 -0.176971801 FBgn0024881 l(2)10206 lethal (2) 10206 http://flybase.net/reports/FBgn0024881.html gene 10206 16-Dec-15 2015_12 "lethal,recessive" FBgn0022146 l(2)k06021 lethal (2) k06021 http://flybase.net/reports/FBgn0022146.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266403 CR45043 http://flybase.net/reports/FBgn0266403.html non_protein_coding_gene CR45043 16-Dec-15 2015_12 FBgn0040319 Gclc Glutamate-cysteine ligase catalytic subunit http://flybase.net/reports/FBgn0040319.html FBgn0029998 protein_coding_gene "0004357=glutamate-cysteine ligase activity, 0005515=protein binding" "0006749=glutathione metabolic process, 0006750=glutathione biosynthetic process, 0006974=cellular response to DNA damage stimulus" "0005634=nucleus, 0048471=perinuclear region of cytoplasm, 0017109=glutamate-cysteine ligase complex" "gclc, GCLC, DmGCLC, 2259, Gcsh, catalytic subunit of glutamate- cysteine ligase, GCL, DmGCS, GCSh, gamma-Glutamylcysteine synthetase, gamma-Glutamylcysteine synthetase catalytic subunit, gamma-glutamylcysteine ligase, Gcs, glutamate cysteine ligase, DmGCSh, glutamate-cysteine ligase, CG2259, GCLc" IPR004308=Glutamate-cysteine ligase catalytic subunit CG2259 16-Dec-15 2015_12 ENSDARG00000013095(gclc) YJL101C(GSH1) WBGene00001527(gcs-1) ENSXETG00000016009(GCLC) ENSMUSG00000032350(Gclc) ENSG00000001084(GCLC) "viable,fertile,long lived,chemical resistant" FBgn0000786 fs(1)BP female sterile (1) BP http://flybase.net/reports/FBgn0000786.html FBgn0000730 gene "fs(1)BP2, fs(1)9F" 16-Dec-15 2015_12 female sterile ovary FBgn0010594 l(2)05315 lethal (2) 05315 http://flybase.net/reports/FBgn0010594.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065250 l(2)SH2134 lethal (2) SH2134 http://flybase.net/reports/FBgn0065250.html gene l(2)SH2 2134 16-Dec-15 2015_12 "lethal,recessive" FBgn0030662 CG9220 http://flybase.net/reports/FBgn0030662.html protein_coding_gene "0015020=glucuronosyltransferase activity, 0008375=acetylglucosaminyltransferase activity, 0008376=acetylgalactosaminyltransferase activity" 0030206=chondroitin sulfate biosynthetic process 0032580=Golgi cisterna membrane dCHSY "IPR029044=Nucleotide-diphospho-sugar transferases, IPR008428=Chondroitin N-acetylgalactosaminyltransferase" CG9220 16-Dec-15 2015_12 WBGene00005023(sqv-5) ENSXETG00000018744(CHSY1) "ENSMUSG00000032640(Chsy1),ENSMUSG00000058152(Chsy3)" "ENSG00000131873(CHSY1),ENSG00000198108(CHSY3)" "viable,body color defective" mesothoracic tergum DRSC20176 K -0.150094943 0.264371295 0.211329532 0.064967036 0.530027072 1.696075484 FBgn0030304 Cyp4g15 Cyp4g15 http://flybase.net/reports/FBgn0030304.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0005506=iron ion binding" "0006694=steroid biosynthetic process, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "152658_at, cytochrome P450, CG11715, 4g15" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG11715 16-Dec-15 2015_12 YDR402C(DIT2) viable FBgn0050263 stum stumble http://flybase.net/reports/FBgn0050263.html "FBgn0034652, FBgn0034653" protein_coding_gene "0050954=sensory perception of mechanical stimulus, 0042330=taxis, 0019230=proprioception" "0030425=dendrite, 0071683=sensory dendrite" "stumble, mdcds_15969, CT35864, CG15679, CG15677, CG30263" IPR026673=SPEC3/C1orf95 CG30263 16-Dec-15 2015_12 "uncoordinated,neurophysiology defective,neuroanatomy defective,viable" "dendrite,multidendritic neuron" FBgn0026202 moch mochtegern http://flybase.net/reports/FBgn0026202.html gene 0007417=central nervous system development mog 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,commissure,midline glial cell,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0060927 l(3)S042202 lethal (3) S042202 http://flybase.net/reports/FBgn0060927.html gene 0422/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031143 CG1532 http://flybase.net/reports/FBgn0031143.html protein_coding_gene 0022008=neurogenesis "IPR025870=Glyoxalase-like domain, IPR029068=Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase" CG1532 16-Dec-15 2015_12 ENSDARG00000042509(glod4) WBGene00006448(glod-4) ENSXETG00000022458(c17orf25) ENSMUSG00000017286(Glod4) ENSG00000167699(GLOD4) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0002179 l(3)62Bc lethal (3) 62Bc http://flybase.net/reports/FBgn0002179.html FBgn0011451 gene "l(3)dre2, dre2" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028900 CG18518 http://flybase.net/reports/FBgn0028900.html FBgn0032573 protein_coding_gene "BG:DS02252.4, DS02252.4" CG18518 16-Dec-15 2015_12 viable FBgn0060630 l(3)S085706 lethal (3) S085706 http://flybase.net/reports/FBgn0060630.html gene 0857/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0005493 l(1)ts4931B lethal (1) ts4931B http://flybase.net/reports/FBgn0005493.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0032646 CG6412 http://flybase.net/reports/FBgn0032646.html protein_coding_gene 0003746=translation elongation factor activity 0006414=translational elongation 0005739=mitochondrion mtEF-Ts "IPR001816=Translation elongation factor EFTs/EF1B, IPR018101=Translation elongation factor Ts, conserved site, IPR014039=Translation elongation factor EFTs/EF1B, dimerisation, IPR009060=UBA-like" CG6412 16-Dec-15 2015_12 ENSDARG00000060748(zgc:158429) WBGene00010094(tsfm-1) ENSXETG00000009653(TSFM) ENSMUSG00000040521(Tsfm) ENSG00000123297(TSFM) "viable,fertile,visible" trichogen cell FBgn0034893 mRpL43 mitochondrial ribosomal protein L43 http://flybase.net/reports/FBgn0034893.html FBgn0063032 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "BcDNA:RE35686, CG5479, mRpL-CI-B8, mitochondrial ribosomal protein L-CI-B8, CI-B8" "IPR012336=Thioredoxin-like fold, IPR007741=Ribosomal protein/NADH dehydrogenase domain" CG5479 16-Dec-15 2015_12 ENSDARG00000045052 YPR100W(MRPL51) WBGene00007712(C25A1.13) ENSXETG00000015206(mrpl43) ENSMUSG00000025208(Mrpl43) "viable,visible" trichogen cell FBgn0028396 TotA Turandot A http://flybase.net/reports/FBgn0028396.html FBgn0051509 protein_coding_gene "0051597=response to methylmercury, 0009408=response to heat, 0009414=response to water deprivation, 0034599=cellular response to oxidative stress, 0034605=cellular response to heat, 0009617=response to bacterium, 0071260=cellular response to mechanical stimulus, 0034644=cellular response to UV, 0046689=response to mercury ion" 0005615=extracellular space "Stress-inducible humoral factor Turandot A, turandot A, Turandot, CG31509, Tot A, totA, Turt, Tot-A, Tot, DIM 31, tot" IPR010825=Stress-inducible humoral factor Turandot CG31509 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,chemical resistant,viable" FBgn0051281 Tpl94D Transition protein-like 94D http://flybase.net/reports/FBgn0051281.html "FBgn0045991, FBgn0046069" protein_coding_gene "0035093=spermatogenesis, exchange of chromosomal proteins" "0000785=chromatin, 0005634=nucleus" "tpl, CG31281, NEST:bs11b10, transition protein-like[94D], Tpl[94D], tpl[94D], tpl94D, NEST:bs30g09" "IPR009071=High mobility group box domain, IPR024460=Protein of unknown function DUF1074" CG31281 16-Dec-15 2015_12 DRSC13593 E -0.244308407 0.939920208 -2.212417984 -0.067406389 -0.075672292 -0.637809064 FBgn0052495 CG32495 http://flybase.net/reports/FBgn0052495.html protein_coding_gene "0005524=ATP binding, 0004363=glutathione synthase activity" "0006750=glutathione biosynthetic process, 0006974=cellular response to DNA damage stimulus, 0071722=detoxification of arsenic-containing substance" "32495, glutathione synthetase, GS" "IPR016185=Pre-ATP-grasp domain, IPR013816=ATP-grasp fold, subdomain 2, IPR014709=Glutathione synthase domain, IPR014049=Glutathione synthase, N-terminal, eukaryotic, IPR014042=Glutathione synthase, alpha-helical, eukaryotic, IPR004887=Glutathione synthase, substrate-binding, eukaryotic, IPR005615=Glutathione synthase, eukaryotic" CG32495 16-Dec-15 2015_12 ENSDARG00000037706(LOC100332067) YOL049W(GSH2) WBGene00010941(M176.2) ENSXETG00000007470(GSS) ENSMUSG00000027610(Gss) ENSG00000100983(GSS) FBgn0011176 l(1)291-54 lethal (1) 291-54 http://flybase.net/reports/FBgn0011176.html FBgn0010199 gene 291-54 16-Dec-15 2015_12 "lethal,recessive" FBgn0042085 Bap170 Brahma associated protein 170kD http://flybase.net/reports/FBgn0042085.html FBgn0027541 protein_coding_gene "0005515=protein binding, 0003677=DNA binding, 0003713=transcription coactivator activity" "0031936=negative regulation of chromatin silencing, 0008586=imaginal disc-derived wing vein morphogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0006909=phagocytosis, 0008587=imaginal disc-derived wing margin morphogenesis, 0050821=protein stabilization, 0045893=positive regulation of transcription, DNA-templated, 0042059=negative regulation of epidermal growth factor receptor signaling pathway" "0005700=polytene chromosome, 0035060=brahma complex, 0070604=PBAF complex" "BAP170, half-life, hfl, bap170, CG3274, BcDNA:GH12174" "IPR003150=DNA-binding RFX-type winged-helix domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR016024=Armadillo-type fold, IPR001606=ARID DNA-binding domain" CG3274 16-Dec-15 2015_12 ENSDARG00000007413(arid2) WBGene00007433(C08B11.3) ENSMUSG00000033237(Arid2) ENSG00000189079(ARID2) "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,visible,partially lethal - majority die,male limited,lethal,female limited,partially,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,eye photoreceptor cell,supernumerary,outer photoreceptor cell,photoreceptor cell R7,cone cell,leg,wing vein,ectopic,wing margin,wing hair,wing sensillum,mesothoracic tergum" FBgn0265586 CR44413 http://flybase.net/reports/FBgn0265586.html non_protein_coding_gene CR44413 16-Dec-15 2015_12 FBgn0024522 l(3)j1E6 lethal (3) j1E6 http://flybase.net/reports/FBgn0024522.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053302 Cpr31A Cuticular protein 31A http://flybase.net/reports/FBgn0053302.html FBgn0032177 protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG4791-PB, CG33302, CG4791" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG33302 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0065277 l(2)SH2045 lethal (2) SH2045 http://flybase.net/reports/FBgn0065277.html gene l(2)SH2 2045 16-Dec-15 2015_12 "lethal,recessive" FBgn0014057 Su(tor)2-408 Su(tor)2-408 http://flybase.net/reports/FBgn0014057.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0085631 CG41360 http://flybase.net/reports/FBgn0085631.html FBan0041360 protein_coding_gene 16-Dec-15 2015_12 FBgn0266539 CG45100 http://flybase.net/reports/FBgn0266539.html protein_coding_gene Dmel_Hdac3_uORF CG45100 16-Dec-15 2015_12 FBgn0052821 CR32821 http://flybase.net/reports/FBgn0052821.html pseudogene_attribute CG32821 CR32821 16-Dec-15 2015_12 FBgn0029915 CG14434 http://flybase.net/reports/FBgn0029915.html protein_coding_gene IPR023577=CYTH-like domain CG14434 16-Dec-15 2015_12 WBGene00018045(F35D11.4) "viable,fertile" FBgn0060407 l(3)S130608 lethal (3) S130608 http://flybase.net/reports/FBgn0060407.html gene 1306/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267520 28SrRNA-ë¬:CR45860 28S ribosomal RNA pseudogene:CR45860 http://flybase.net/reports/FBgn0267520.html pseudogene_attribute CR45860 CR45860 16-Dec-15 2015_12 FBgn0051415 CG31415 http://flybase.net/reports/FBgn0051415.html FBgn0046083 protein_coding_gene NEST:bs07c11 CG31415 16-Dec-15 2015_12 FBgn0030974 CG7358 http://flybase.net/reports/FBgn0030974.html protein_coding_gene CG7358 16-Dec-15 2015_12 ENSDARG00000037177(LOC560041) ENSG00000123200(ZC3H13) "viable,visible" mesothoracic tergum FBgn0000065 Aldox-1 Aldehyde oxidase 1 http://flybase.net/reports/FBgn0000065.html gene 0004031=aldehyde oxidase activity "Ao, AO, Aldox, Aox, aldehyde oxidase-1, aldox, low aldehyde oxidase, Ao-1, AOX, lao" 16-Dec-15 2015_12 "electrophoretic variant,slow,viable,fast" FBgn0028158 l(3)S041706 lethal (3) S041706 http://flybase.net/reports/FBgn0028158.html gene 0417/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0037064 CG9389 http://flybase.net/reports/FBgn0037064.html protein_coding_gene 0008934=inositol monophosphate 1-phosphatase activity "0016311=dephosphorylation, 0046854=phosphatidylinositol phosphorylation, 0046855=inositol phosphate dephosphorylation" 0005737=cytoplasm "142336_at, IMP" "IPR020583=Inositol monophosphatase, metal-binding site, IPR020552=Inositol monophosphatase, Lithium-sensitive, IPR000760=Inositol monophosphatase, IPR020550=Inositol monophosphatase, conserved site" CG9389 16-Dec-15 2015_12 viable FBgn0001021 fs(3)A12 female sterile (3) A12 http://flybase.net/reports/FBgn0001021.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0022303 l(1)L55.6 lethal (1) L55.6 http://flybase.net/reports/FBgn0022303.html gene L55.6 16-Dec-15 2015_12 "lethal,recessive" FBgn0065116 l(3)SH159 lethal (3) SH159 http://flybase.net/reports/FBgn0065116.html gene l(2)SH3 159 16-Dec-15 2015_12 "lethal,recessive" FBgn0036450 Tdrd3 tudor domain containing 3 ortholog (H.sapiens) http://flybase.net/reports/FBgn0036450.html protein_coding_gene 0003723=RNA binding "0006397=mRNA processing, 0046331=lateral inhibition" "0005737=cytoplasm, 0005634=nucleus" "CG13472, dTDRD3" "IPR010304=Survival motor neuron, IPR015940=Ubiquitin-associated domain, IPR009060=UBA-like, IPR002999=Tudor domain, IPR013894=RecQ mediated genome instability protein, N-terminal" CG13472 16-Dec-15 2015_12 ENSDARG00000025421(zgc:77174) WBGene00021748(Y50D4C.3) ENSMUSG00000022019(Tdrd3) ENSG00000083544(TDRD3) "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0036156 CG11726 http://flybase.net/reports/FBgn0036156.html protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" cg11726 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG11726 16-Dec-15 2015_12 viable FBgn0264835 CR44043 http://flybase.net/reports/FBgn0264835.html non_protein_coding_gene CR44043 16-Dec-15 2015_12 FBgn0067875 Mod(Prat:bw)3-11 Mod(Prat:bw)3-11 http://flybase.net/reports/FBgn0067875.html gene Mod-3-11 16-Dec-15 2015_12 FBgn0265063 CG44174 http://flybase.net/reports/FBgn0265063.html protein_coding_gene lincRNA.811 CG44174 16-Dec-15 2015_12 FBgn0262429 mir-13a mir-13a stem loop http://flybase.net/reports/FBgn0262429.html "FBgn0046830, FBgn0082180, FBgn0262277" miRNA_gene 0005844=polysome "CR32931, CR42984, mir-13a*, miR13a, dme-mir-13a, mir-13a, MiR-13a, dme-miR-13a, miR-13a, mir-13, mir-13aS, miR-13, 13a, CR33566" CR42984 16-Dec-15 2015_12 embryonic stage -- adult stage "visible,partially lethal - majority die,some die during pharate adult stage,lethal" wing FBgn0085818 CR41608 http://flybase.net/reports/FBgn0085818.html FBan0041608 rRNA_gene CR41608 16-Dec-15 2015_12 FBgn0263839 CR43701 http://flybase.net/reports/FBgn0263839.html non_protein_coding_gene ncRNA_54 CR43701 16-Dec-15 2015_12 FBgn0262901 CR43256 http://flybase.net/reports/FBgn0262901.html non_protein_coding_gene CR43256 16-Dec-15 2015_12 FBgn0261571 CG42685 http://flybase.net/reports/FBgn0261571.html "FBgn0053482, FBgn0028854, FBgn0260445" protein_coding_gene "DS07721.6, BG:DS07721.6, DS07721.6-like protein, CG33482, CG12636" "IPR002859=PKD/REJ-like domain, IPR001024=PLAT/LH2 domain" CG42685 16-Dec-15 2015_12 FBgn0032834 CG13965 http://flybase.net/reports/FBgn0032834.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG13965 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028378 fs(1)3B fs(1)3B http://flybase.net/reports/FBgn0028378.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0023536 CG3156 http://flybase.net/reports/FBgn0023536.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding, 0015421=oligopeptide-transporting ATPase activity, 0008559=xenobiotic-transporting ATPase activity" "0006839=mitochondrial transport, 0055085=transmembrane transport, 0006783=heme biosynthetic process" "0005886=plasma membrane, 0005743=mitochondrial inner membrane, 0016021=integral component of membrane" EG:171D11.2 "IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3156 16-Dec-15 2015_12 ENSDARG00000061591(abcb10) "YLR188W(MDL1),YPL270W(MDL2)" "WBGene00001813(haf-3),WBGene00001811(haf-1)" ENSXETG00000022887(ABCB10) ENSMUSG00000031974(Abcb10) "ENSG00000135776(ABCB10),ENSG00000220107" "viable,fertile" FBgn0052715 CG32715 http://flybase.net/reports/FBgn0052715.html protein_coding_gene 16-Dec-15 2015_12 FBgn0261701 CG42737 http://flybase.net/reports/FBgn0261701.html protein_coding_gene CG43202 16-Dec-15 2015_12 FBgn0060816 l(3)S052813b lethal (3) S052813b http://flybase.net/reports/FBgn0060816.html gene 0528/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0027358 Tim9b Translocase of inner membrane 9b http://flybase.net/reports/FBgn0027358.html FBgn0053066 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0071456=cellular response to hypoxia, 0015031=protein transport, 0006626=protein targeting to mitochondrion" 0005744=mitochondrial inner membrane presequence translocase complex "Tim9, CG17767, tim9, Dromel_CG12788_CG17767_FBtr0074_tim9b_uORF, CG33066, Tim9b" IPR004217=Tim10/DDP family zinc finger CG17767 16-Dec-15 2015_12 ENSG00000132286(FXC1) FBgn0265632 CG44439 http://flybase.net/reports/FBgn0265632.html protein_coding_gene lincRNA.265 CG44439 16-Dec-15 2015_12 FBgn0011810 l(3)s2976 lethal (3) s2976 http://flybase.net/reports/FBgn0011810.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0019811 ftl2 flightless-2nd http://flybase.net/reports/FBgn0019811.html gene 16-Dec-15 2015_12 flightless FBgn0266809 CR45271 http://flybase.net/reports/FBgn0266809.html non_protein_coding_gene CR45271 16-Dec-15 2015_12 FBgn0062605 Mod(var)1420 Mod(var)1420 http://flybase.net/reports/FBgn0062605.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1420 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0030081 CG7246 http://flybase.net/reports/FBgn0030081.html protein_coding_gene "0040018=positive regulation of multicellular organism growth, 0022008=neurogenesis, 0009267=cellular response to starvation, 0006396=RNA processing" 0005622=intracellular dUTP6 "IPR003107=HAT (Half-A-TPR) repeat, IPR013949=U3 small nucleolar RNA-associated protein 6" CG7246 16-Dec-15 2015_12 ENSDARG00000035730(utp6) YDR449C(UTP6) ENSXETG00000020057(UTP6) ENSMUSG00000035575(Utp6) ENSG00000108651(UTP6) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0039963 CG17444 http://flybase.net/reports/FBgn0039963.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019823 eH3 eH3 http://flybase.net/reports/FBgn0019823.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0038619 CG7685 http://flybase.net/reports/FBgn0038619.html protein_coding_gene "0004558=alpha-1,4-glucosidase activity" 0017177=glucosidase II complex "IPR028146=Glucosidase II beta subunit, N-terminal, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat" CG7685 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0050403 CG30403 http://flybase.net/reports/FBgn0050403.html FBgn0047139 protein_coding_gene 0003677=DNA binding BcDNA:RE26725 "IPR006578=MADF domain, IPR004210=BESS motif" CG30403 16-Dec-15 2015_12 "viable,visible,lethal" trichogen cell FBgn0046649 anon-38D.17 anon-38D.17 http://flybase.net/reports/FBgn0046649.html gene 38D.17 16-Dec-15 2015_12 FBgn0019829 da::h da::h http://flybase.net/reports/FBgn0019829.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0260090 2L3707 http://flybase.net/reports/FBgn0260090.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0052189 CG32189 http://flybase.net/reports/FBgn0052189.html FBgn0061401 protein_coding_gene BcDNA:RE39957 CG32189 16-Dec-15 2015_12 viable FBgn0000128 Ars-region6 Autonomous replicating sequence region 6 http://flybase.net/reports/FBgn0000128.html region "Ars sequence 6, ars406, Ars6" 16-Dec-15 2015_12 FBgn0033589 CG13227 http://flybase.net/reports/FBgn0033589.html protein_coding_gene cg13227 CG13227 16-Dec-15 2015_12 viable DRSC06347 I -1.627129847 0.591195776 -0.007441081 0.181026469 0.755501226 1.234691741 FBgn0051928 CG31928 http://flybase.net/reports/FBgn0051928.html FBgn0031342 protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis 0042600=chorion CG10872 "IPR001461=Aspartic peptidase, IPR021109=Aspartic peptidase domain" CG31928 16-Dec-15 2015_12 viable FBgn0041601 g5 g5 http://flybase.net/reports/FBgn0041601.html gene 16-Dec-15 2015_12 FBgn0038788 Sirt2 Sirtuin 2 http://flybase.net/reports/FBgn0038788.html protein_coding_gene "0008270=zinc ion binding, 0004407=histone deacetylase activity, 0070403=NAD+ binding, 0017136=NAD-dependent histone deacetylase activity" "0006476=protein deacetylation, 0008340=determination of adult lifespan, 0016575=histone deacetylation, 0048813=dendrite morphogenesis" "0005737=cytoplasm, 0005634=nucleus" "dSIRT2, SIRT2, D.mel2, Sirt2, CG5085" "IPR017328=Sirtuin, class I, IPR029035=DHS-like NAD/FAD-binding domain, IPR026590=Sirtuin family, catalytic core domain, IPR026591=Sirtuin family, catalytic core small domain, IPR003000=Sirtuin family" CG5085 16-Dec-15 2015_12 ENSDARG00000011488(sirt2) YPL015C(HST2) ENSXETG00000002409(SIRT2) ENSMUSG00000015149(Sirt2) ENSG00000068903(SIRT2) "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable" FBgn0029694 CG15375 http://flybase.net/reports/FBgn0029694.html protein_coding_gene mdcds_59461 CG15375 16-Dec-15 2015_12 FBgn0004702 l(2)56Fd lethal (2) 56Fd http://flybase.net/reports/FBgn0004702.html gene l(2)56F 16-Dec-15 2015_12 lethal FBgn0085349 CR34320 http://flybase.net/reports/FBgn0085349.html pseudogene_attribute CG34320 CR34320 16-Dec-15 2015_12 FBgn0045856 e(Pi3K92E)delta e(Pi3K92E)delta http://flybase.net/reports/FBgn0045856.html gene delta 16-Dec-15 2015_12 FBgn0028691 Rpn9 Regulatory particle non-ATPase 9 http://flybase.net/reports/FBgn0028691.html FBgn0028103 protein_coding_gene "0007096=regulation of exit from mitosis, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005838=proteasome regulatory particle, 0000502=proteasome complex, 0008541=proteasome regulatory particle, lid subcomplex" "l(3)S071806b, 718/06, CT28749, CG10230, l(3)S071806, Rpn9, rpn9, 0718/06, S11, Nobody, p39A, Rpn94, Rpn4, PSMD13" IPR000717=Proteasome component (PCI) domain CG10230 16-Dec-15 2015_12 "ENSDARG00000052098,ENSDARG00000016239(psmd13)" YDR427W(RPN9) WBGene00004465(rpn-9) ENSXETG00000008827(psmd13) ENSMUSG00000025487(Psmd13) ENSG00000185627(PSMD13) "neuroanatomy defective,partially lethal - majority die,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage" rhabdomere of eye photoreceptor cell DRSC27177 IEK -0.382995876 -2.534154536 -2.255090635 -1.028416817 0.736823151 1.621169621 FBgn0000198 blo bloated http://flybase.net/reports/FBgn0000198.html FBgn0020848 gene "0007229=integrin-mediated signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0016337=single organismal cell-cell adhesion, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces" "ba[33f26], kit, balloon, ba[2], kitikete, ba" 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,poor" "wing,wing vein,ectopic,somatic clone,cell non-autonomous,macrochaeta" FBgn0060702 l(3)S071615 lethal (3) S071615 http://flybase.net/reports/FBgn0060702.html gene 0716/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002138 l(2)K255 lethal (2) K255 http://flybase.net/reports/FBgn0002138.html gene 16-Dec-15 2015_12 lethal FBgn0082974 snoRNA:ë¬28S-3305c snoRNA:ë¬28S-3305c http://flybase.net/reports/FBgn0082974.html snoRNA_gene "psi28s-3305c, CR34624" CR34624 16-Dec-15 2015_12 FBgn0067655 sd-13 sd-13 http://flybase.net/reports/FBgn0067655.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 13 16-Dec-15 2015_12 "neurophysiology defective,somatic clone,lethal,recessive,phototaxis defective" FBgn0043857 rempD reduced mechanoreceptor potentials D http://flybase.net/reports/FBgn0043857.html gene 0007605=sensory perception of sound 16-Dec-15 2015_12 "auditory perception defective,recessive,uncoordinated,locomotor behavior defective,behavior defective" "wing,leg,adult antennal nerve" FBgn0261479 nero nero http://flybase.net/reports/FBgn0261479.html "FBgn0069094, FBgn0011013, FBgn0039871" protein_coding_gene 0019135=deoxyhypusine monooxygenase activity "0007423=sensory organ development, 0008283=cell proliferation, 0008612=peptidyl-lysine modification to peptidyl-hypusine, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0016049=cell growth, 0010508=positive regulation of autophagy" 0005789=endoplasmic reticulum membrane "CG2245, l(3)s1921, DOHH, lethal (3) s1921, deoxyhypusine hydroxylase" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR004155=PBS lyase HEAT-like repeat, IPR027517=Deoxyhypusine hydroxylase" CG2245 16-Dec-15 2015_12 ENSDARG00000003564(LOC100332103) YJR070C(LIA1) WBGene00007555(tag-242) ENSXETG00000008150(DOHH) ENSMUSG00000020236(Dohh) ENSG00000129932(DOHH) FBgn0024841 Pcd pterin-4a-carbinolamine dehydratase http://flybase.net/reports/FBgn0024841.html FBgn0063104 protein_coding_gene 0008124=4-alpha-hydroxytetrahydrobiopterin dehydratase activity 0006729=tetrahydrobiopterin biosynthetic process "BcDNA:LP07248, pterin-4a-carbinolamine dehydratase, pterin-4A-carbinolamine dehydratase, PCD, CG1963" IPR001533=Transcriptional coactivator/pterin dehydratase CG1963 16-Dec-15 2015_12 WBGene00020397(pcbd-1) "ENSMUSG00000021496(Pcbd2),ENSMUSG00000020098(Pcbd1)" "viable,fertile,lethal,partially lethal - majority die,visible" trichogen cell DRSC16785 I -0.240113592 2.581568071 0.488008241 1.463786069 -1.476387284 -0.349172999 FBgn0032431 CG5435 http://flybase.net/reports/FBgn0032431.html FBgn0063346 protein_coding_gene BcDNA:AT11334 IPR022179=Protein of unknown function DUF3695 CG5435 16-Dec-15 2015_12 ENSMUSG00000027886(1700013F07Rik) "ENSG00000215716,ENSG00000179902(C1orf194)" viable FBgn0265749 CR44556 http://flybase.net/reports/FBgn0265749.html non_protein_coding_gene lincRNA.978 CR44556 16-Dec-15 2015_12 FBgn0003582 Su(Ste) Suppressor of Stellate http://flybase.net/reports/FBgn0003582.html "FBgn0005668, FBgn0025265" 0019887=protein kinase regulator activity 0007060=male meiosis chromosome segregation 0005956=protein kinase CK2 complex "rasi1, PSY, heterochromatic moderate repeat, anon-fast-evolving-1B7, Su(ste), su(ste), HMR-element, rasi4, Ste, HMR, Suppressors of Stellate, crystal, SuSte, Heterochromatic Moderately Repetitive element, anon-EST:fe1B7, suppressor of ste, cry, Stellate suppressor" "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet" 16-Dec-15 2015_12 "male fertile,reduced,meiotic cell cycle defective,male" FBgn0028560 sut4 sugar transporter 4 http://flybase.net/reports/FBgn0028560.html protein_coding_gene "0005351=sugar:proton symporter activity, 0005355=glucose transmembrane transporter activity" 0055085=transmembrane transport 0016021=integral component of membrane CG1380 "IPR005828=Major facilitator, sugar transporter-like, IPR003663=Sugar/inositol transporter, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG1380 16-Dec-15 2015_12 "ENSDARG00000020344(slc2a8),ENSDARG00000058731(LOC560602)" "YLR081W(GAL2),YDR343C(HXT6),YDR342C(HXT7),YHR092C(HXT4),YJL214W(HXT8),YDR345C(HXT3),YHR094C(HXT1),YHR096C(HXT5),YJL219W(HXT9),YOL156W(HXT11),YMR011W(HXT2),YFL011W(HXT10),YNR072W(HXT17),YEL069C(HXT13),YDL245C(HXT15),YJR158W(HXT16)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0014028 SdhB "Succinate dehydrogenase, subunit B (iron-sulfur)" http://flybase.net/reports/FBgn0014028.html protein_coding_gene "0048039=ubiquinone binding, 0051539=4 iron, 4 sulfur cluster binding, 0051538=3 iron, 4 sulfur cluster binding, 0008177=succinate dehydrogenase (ubiquinone) activity, 0009055=electron carrier activity, 0051537=2 iron, 2 sulfur cluster binding" "0006121=mitochondrial electron transport, succinate to ubiquinone, 0006099=tricarboxylic acid cycle" "0005743=mitochondrial inner membrane, 0005875=microtubule associated complex, 0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)" "SDH-Ip, SDHb, COMPLEX II: iron-sulfur subunit, CG3283, Ip, succinate dehydrogenase B, iron-sulfur protein subunit of succinate dehydrogenase, Succinate dehydrogenase Iron-sulfur protein, succinate dehydrogenase subunit b, CII-SDHB, Succinate dehydrogenase [ubiquinone] iron-sulfur protein, DHSB, SDH, Succinate dehydrogenase Iron Protein, sdhB, SDH-IP, Succinate dehydrogenase B, SDH-B, succinate dehydrogenase, Succinate dehydrogenase Iron-sulfur" "IPR009051=Alpha-helical ferredoxin, IPR025192=Succinate dehydogenase/fumarate reductase N-terminal, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR004489=Succinate dehydrogenase/fumarate reductase iron-sulphur protein, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR012675=Beta-grasp domain, IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900=4Fe-4S ferredoxin, iron-sulphur binding, conserved site" CG3283 16-Dec-15 2015_12 YLL041C(SDH2) WBGene00006433(sdhb-1) ENSXETG00000013435(SDHB) ENSMUSG00000009863(Sdhb) ENSG00000117118(SDHB) " larval stage && adult stage , adult stage " " adult thorax

, adult head

" "viable,fertile,gravitaxis defective,stress response defective" "mitochondrion,mitochondrial crista,flight muscle" FBgn0024859 l(3)96Bc lethal (3) 96Bc http://flybase.net/reports/FBgn0024859.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259530 GG01329 http://flybase.net/reports/FBgn0259530.html gene 16-Dec-15 2015_12 visible proboscis FBgn0001849 l(1)ts5141 lethal (1) ts5141 http://flybase.net/reports/FBgn0001849.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0037123 CG14569 http://flybase.net/reports/FBgn0037123.html protein_coding_gene CG14569 16-Dec-15 2015_12 viable FBgn0265943 CR44730 http://flybase.net/reports/FBgn0265943.html non_protein_coding_gene lincRNA.133 CR44730 16-Dec-15 2015_12 FBgn0037763 CG16904 http://flybase.net/reports/FBgn0037763.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane IPR002076=ELO family CG16904 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" DRSC25306 K 0.582475653 0.037152286 -0.283659855 0.129217217 1.789222779 1.051342966 FBgn0085447 sif still life http://flybase.net/reports/FBgn0085447.html "FBan0032414, FBgn0035629, FBgn0035628, FBgn0019656, FBgn0052414, FBgn0019652" protein_coding_gene "0030676=Rac guanyl-nucleotide exchange factor activity, 0005089=Rho guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity, 0005057=receptor signaling protein activity" "0030036=actin cytoskeleton organization, 0050770=regulation of axonogenesis, 0051491=positive regulation of filopodium assembly, 0043087=regulation of GTPase activity, 0050803=regulation of synapse structure or activity, 0007268=synaptic transmission" 0045202=synapse "RhoGEF, Still Life, still-life, CG5256, CG32414, CG5406, lincRNA.447, SIF, still life type 2, Sif, still life type 1, Still life, slf, Dm_3L:26493, unnamed, CG34418, still life" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000219=Dbl homology (DH) domain, IPR001478=PDZ domain, IPR003116=Raf-like Ras-binding, IPR000697=WH1/EVH1 domain, IPR001331=Guanine-nucleotide dissociation stimulator, CDC24, conserved site, IPR001849=Pleckstrin homology domain" CG34418 16-Dec-15 2015_12 " embryonic stage | stage 17 , embryonic stage | stage 14 " " ventral nerve cord

, embryonic brain

, embryonic central nervous system | segmentally repeated pattern

, embryonic central nervous system | restricted

" " embryonic stage | stage 17 , adult stage , larval stage | third instar " " neuropil

, medulla neuropil

, ventral nerve cord

, lobula plate neuropil

, bouton &&of neuromuscular junction

, lamina neuropil

" FBgn0052152 CG32152 http://flybase.net/reports/FBgn0052152.html protein_coding_gene 0016274=protein-arginine N-methyltransferase activity 0006479=protein methylation "IPR025799=Protein arginine N-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG32152 16-Dec-15 2015_12 "viable,fertile" FBgn0015841 Vm39DE Vm39DE http://flybase.net/reports/FBgn0015841.html gene T[[1]] 16-Dec-15 2015_12 FBgn0260645 CG42537 http://flybase.net/reports/FBgn0260645.html FBgn0037441 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "BRG-A3, CG10284" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42537 16-Dec-15 2015_12 FBgn0028036 l(3)S101206b lethal (3) S101206b http://flybase.net/reports/FBgn0028036.html gene "l(3)S101206, 1012/06" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0265900 CR44689 http://flybase.net/reports/FBgn0265900.html non_protein_coding_gene CR44689 16-Dec-15 2015_12 FBgn0065470 l(2)SH1334 lethal (2) SH1334 http://flybase.net/reports/FBgn0065470.html gene l(2)SH2 1334 16-Dec-15 2015_12 "lethal,recessive" FBgn0263590 CR43615 http://flybase.net/reports/FBgn0263590.html non_protein_coding_gene CR43615 16-Dec-15 2015_12 FBgn0053057 CG33057 http://flybase.net/reports/FBgn0053057.html protein_coding_gene "0008665=2'-phosphotransferase activity, 0016772=transferase activity, transferring phosphorus-containing groups" "0006388=tRNA splicing, via endonucleolytic cleavage and ligation" IPR002745=Phosphotransferase KptA/Tpt1 CG33057 16-Dec-15 2015_12 ENSDARG00000037628(zgc:113138) YOL102C(TPT1) ENSXETG00000007196(TRPT1) ENSMUSG00000047656(Trpt1) ENSG00000149743(TRPT1) "viable,fertile" FBgn0085766 CR40679 http://flybase.net/reports/FBgn0085766.html FBan0040679 rRNA_gene CR40679 16-Dec-15 2015_12 FBgn0263021 CG43316 http://flybase.net/reports/FBgn0263021.html "FBan0013169, FBgn0033704" protein_coding_gene CG13169 CG43316 16-Dec-15 2015_12 FBgn0069077 tkv::wit tkv::wit http://flybase.net/reports/FBgn0069077.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0003980 Vm26Ab Vitelline membrane 26Ab http://flybase.net/reports/FBgn0003980.html protein_coding_gene 0008316=structural constituent of vitelline membrane "0009617=response to bacterium, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation, 0007304=chorion-containing eggshell formation, 0007343=egg activation" 0060388=vitelline envelope "Sv23, fs(2)QJ42, TU-4, sV23, sv23, Dm sV23, CG9046, sV26, Vm26A, VM26A.2, DIM 29" IPR013135=Vitelline membrane cysteine-rich domain CG9046 16-Dec-15 2015_12 " oogenesis stage | stage S8-11 , adult stage && oogenesis stage " follicle cell

" oogenesis stage | stage S9-14 , embryonic stage " vitelline membrane

"female sterile,female semi-sterile" "endochorion,egg" FBgn0085280 CG34251 http://flybase.net/reports/FBgn0085280.html protein_coding_gene CG34251 16-Dec-15 2015_12 FBgn0034915 eIF6 eIF6 http://flybase.net/reports/FBgn0034915.html "FBgn0021890, FBgn0046444, FBgn0046445" protein_coding_gene "0003743=translation initiation factor activity, 0043022=ribosome binding" "0042256=mature ribosome assembly, 0009267=cellular response to starvation, 0006412=translation, 0006413=translational initiation" 0005829=cytosol "DeIF6, eif6, unnamed, elF6, l(2)k13214, CG17611, anon-WO0172774.153, anon-WO0172774.155" IPR002769=Translation initiation factor IF6 CG17611 16-Dec-15 2015_12 ENSDARG00000020232(eif6) YPR016C(TIF6) WBGene00001234(eif-6) ENSXETG00000026867(itgb4bp) ENSMUSG00000027613(Eif6) ENSG00000126005 "visible,lethal,recessive,partially lethal,some die during pupal stage" "wing,sex comb,tarsal segment" FBgn0069315 X-189-23 X-189-23 http://flybase.net/reports/FBgn0069315.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0014970 jal jalapeno http://flybase.net/reports/FBgn0014970.html gene 16-Dec-15 2015_12 FBgn0053362 5SrRNA:CR33362 5SrRNA:CR33362 http://flybase.net/reports/FBgn0053362.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33362 CR33362 16-Dec-15 2015_12 FBgn0003103 PL(3)sp-T1 Polygenic locus sternopleural T1 http://flybase.net/reports/FBgn0003103.html gene "PL(3)sp[T1], 3a" 16-Dec-15 2015_12 FBgn0013310 PC-Pld Phosphatidylcholine-specific phospholipase-D http://flybase.net/reports/FBgn0013310.html gene 0004630=phospholipase D activity 16-Dec-15 2015_12 FBgn0052021 CG32021 http://flybase.net/reports/FBgn0052021.html FBgn0062879 protein_coding_gene 0046331=lateral inhibition BcDNA:SD15619 16-Dec-15 2015_12 "lethal,recessive,viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0265873 CR44662 http://flybase.net/reports/FBgn0265873.html non_protein_coding_gene lincRNA.996 CR44662 16-Dec-15 2015_12 FBgn0052641 CG32641 http://flybase.net/reports/FBgn0052641.html protein_coding_gene 0009408=response to heat "IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site" CG32641 16-Dec-15 2015_12 DRSC22885 K -0.086617103 -1.032778946 0.011911982 0.252530775 -1.830134857 -0.72855551 FBgn0030634 CG9164 http://flybase.net/reports/FBgn0030634.html protein_coding_gene IPR027417=P-loop containing nucleoside triphosphate hydrolase CG9164 16-Dec-15 2015_12 "ENSDARG00000061819(wscd2),ENSDARG00000060269" "ENSXETG00000006816(WSCD1),ENSXETG00000011472(WSCD2)" "ENSMUSG00000020811(Wscd1),ENSMUSG00000063430(Wscd2)" "ENSG00000075035(WSCD2),ENSG00000179314(WSCD1)" "viable,fertile" FBgn0043000 CycB::pim CycB::pim http://flybase.net/reports/FBgn0043000.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,wild-type" FBgn0259864 Su(Ste):CR42433 Su(Ste):CR42433 http://flybase.net/reports/FBgn0259864.html non_protein_coding_gene "RR42328, CR42433" CR42433 16-Dec-15 2015_12 FBgn0022240 l(2)k02501 lethal (2) k02501 http://flybase.net/reports/FBgn0022240.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085459 CG34430 http://flybase.net/reports/FBgn0085459.html "FBgn0033237, FBan0014766" protein_coding_gene CG14766 IPR006214=Bax inhibitor 1-related CG34430 16-Dec-15 2015_12 FBgn0028165 l(3)S032412 lethal (3) S032412 http://flybase.net/reports/FBgn0028165.html gene 0324/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0060749 l(3)S065109 lethal (3) S065109 http://flybase.net/reports/FBgn0060749.html gene 0651/09 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065904 l(2)SH0194 lethal (2) SH0194 http://flybase.net/reports/FBgn0065904.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014973 l(1)13Fc lethal (1) 13Fc http://flybase.net/reports/FBgn0014973.html gene "VIII, l(1)VIII" 16-Dec-15 2015_12 "lethal,recessive" FBgn0058471 CR40471 http://flybase.net/reports/FBgn0058471.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0265896 CR44685 http://flybase.net/reports/FBgn0265896.html non_protein_coding_gene lincRNA.635 CR44685 16-Dec-15 2015_12 FBgn0013758 C8.5 C8.5 http://flybase.net/reports/FBgn0013758.html gene T-C8.5 16-Dec-15 2015_12 FBgn0050109 CG30109 http://flybase.net/reports/FBgn0050109.html protein_coding_gene IPR007918=Mitochondrial distribution/morphology family 35/apoptosis CG30109 16-Dec-15 2015_12 ENSDARG00000014963(zgc:112025) YKL053C-A(MDM35) WBGene00011635(T09A5.7) ENSXETG00000012223(TRIAP1) ENSMUSG00000029535(Triap1) ENSG00000170855(TRIAP1) "viable,fertile" FBgn0082683 E(ftz)2955 E(ftz)2955 http://flybase.net/reports/FBgn0082683.html gene 2955 16-Dec-15 2015_12 FBgn0033928 Arc2 Arc2 http://flybase.net/reports/FBgn0033928.html "FBgn0061987, FBgn0062886" protein_coding_gene "dArc2, dARC2, CG13941, anon-WO0118547.456, BcDNA:SD11637" CG13941 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0021891 l(2)k13211 lethal (2) k13211 http://flybase.net/reports/FBgn0021891.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023088 eggroll eggroll http://flybase.net/reports/FBgn0023088.html gene 16-Dec-15 2015_12 "aging defective,recessive" "lamina,medulla,adult brain,retina,glial cell,neuron,neuropil,embryonic/larval brain" FBgn0065517 l(2)SH1141 lethal (2) SH1141 http://flybase.net/reports/FBgn0065517.html gene l(2)SH2 1141 16-Dec-15 2015_12 "lethal,recessive" FBgn0261595 M(2)50E Minute (2) 50E http://flybase.net/reports/FBgn0261595.html gene 16-Dec-15 2015_12 FBgn0083291 E(smoDN)2038 Enhancer of smoDN 2038 http://flybase.net/reports/FBgn0083291.html gene 16-Dec-15 2015_12 FBgn0038893 CG6353 http://flybase.net/reports/FBgn0038893.html FBgn0064770 protein_coding_gene 0022008=neurogenesis BcDNA:SD28072 "IPR023572=Archease domain, IPR002804=Archease" CG6353 16-Dec-15 2015_12 ENSDARG00000016368(zbtb8os) WBGene00016621(C43H8.1) ENSXETG00000000982(ZBTB8OS) ENSMUSG00000057572(Zbtb8os) "ENSG00000176261(ZBTB8OS),ENSG00000183432,ENSG00000172799" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0032163 TbCMF46 TbCMF46 http://flybase.net/reports/FBgn0032163.html protein_coding_gene 0008599=protein phosphatase type 1 regulator activity "0000164=protein phosphatase type 1 complex, 0005929=cilium" "mel CG13125, CT32363, CG13125" IPR001611=Leucine-rich repeat CG13125 16-Dec-15 2015_12 ENSDARG00000041300(lrrc48) WBGene00019842(R02F11.4) ENSXETG00000012155(LRRC48) ENSMUSG00000056598(Lrrc48) ENSG00000171962(LRRC48) viable FBgn0267319 CR45755 http://flybase.net/reports/FBgn0267319.html non_protein_coding_gene CR45755 16-Dec-15 2015_12 FBgn0266559 EP2083 http://flybase.net/reports/FBgn0266559.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0010701 l(2)s4989 lethal (2) s4989 http://flybase.net/reports/FBgn0010701.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262008 CG42826 http://flybase.net/reports/FBgn0262008.html "FBan0006640, FBgn0036068, FBgn0044601" protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CG6640 "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG42826 16-Dec-15 2015_12 FBgn0085614 CG41323 http://flybase.net/reports/FBgn0085614.html FBan0041323 protein_coding_gene 16-Dec-15 2015_12 FBgn0013308 Odc2 Ornithine decarboxylase 2 http://flybase.net/reports/FBgn0013308.html FBgn0002984 protein_coding_gene 0004586=ornithine decarboxylase activity 0006596=polyamine biosynthetic process "dodc2, CG8719" "IPR029066=PLP-binding barrel, IPR022653=Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site, IPR002433=Ornithine decarboxylase, IPR009006=Alanine racemase/group IV decarboxylase, C-terminal, IPR000183=Ornithine/DAP/Arg decarboxylase, IPR022644=Orn/DAP/Arg decarboxylase 2, N-terminal, IPR022643=Orn/DAP/Arg decarboxylase 2, C-terminal" CG8719 16-Dec-15 2015_12 ENSDARG00000007377(odc1) YKL184W(SPE1) WBGene00003844(odc-1) "ENSXETG00000003519(odc1),ENSXETG00000007373(TNeu085h23.1),ENSXETG00000004118(azin1)" "ENSMUSG00000011179(Odc1),ENSMUSG00000028789(Adc),ENSMUSG00000037458(Azin1),ENSMUSG00000023120(Gm853)" "ENSG00000115758(ODC1),ENSG00000142920(ADC),ENSG00000155096(AZIN1)" viable FBgn0265202 CR44262 http://flybase.net/reports/FBgn0265202.html non_protein_coding_gene CR44262 16-Dec-15 2015_12 FBgn0259961 CG42471 http://flybase.net/reports/FBgn0259961.html protein_coding_gene CG42471 16-Dec-15 2015_12 FBgn0011289 TfIIA-L Transcription factor IIA L http://flybase.net/reports/FBgn0011289.html protein_coding_gene "0001129=TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly, 0001094=TFIID-class transcription factor binding, 0017025=TBP-class protein binding, 0001128=RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly" "0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005672=transcription factor TFIIA complex, 0005634=nucleus" "TFIIAL, CT18631, TFIIA-L, dTFIIA, CG5930, TFIIA, tfiia-l" "IPR009088=Transcription factor IIA, beta-barrel, IPR013028=Transcription factor IIA, alpha subunit, N-terminal, IPR009083=Transcription factor IIA, helical, IPR004855=Transcription factor IIA, alpha/beta subunit" CG5930 16-Dec-15 2015_12 ENSDARG00000011000(gtf2a1) YOR194C(TOA1) WBGene00004136(pqn-51) ENSXETG00000010036(gtf2a1) ENSMUSG00000020962(Gtf2a1) ENSG00000165417(GTF2A1) "viable,fertile" DRSC16882 EK -0.674354735 0.593174026 -1.332734098 1.530427732 1.267506297 2.346933359 FBgn0028135 l(3)S050407a lethal (3) S050407a http://flybase.net/reports/FBgn0028135.html gene "0504/07, 504/7" 16-Dec-15 2015_12 "lethal,recessive" FBgn0030956 CG18259 http://flybase.net/reports/FBgn0030956.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG18259 16-Dec-15 2015_12 ENSXETG00000013412(poldip3) ENSMUSG00000041815(Poldip3) FBgn0019755 l(1)75B5 lethal (1) 75B5 http://flybase.net/reports/FBgn0019755.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065951 l(2)SH0071 lethal (2) SH0071 http://flybase.net/reports/FBgn0065951.html gene l(2)SH2 0071 16-Dec-15 2015_12 "lethal,recessive" FBgn0020640 Lcp65Ae Lcp65Ae http://flybase.net/reports/FBgn0020640.html FBgn0035683 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Lcp-e, DCP6, DMLCP65e, DmelLcp65Ae, CG10529" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG10529 16-Dec-15 2015_12 " larval stage , pupal stage | 7-13 hr , embryonic stage " viable DRSC11212 E -0.900860278 -0.75881763 0.315817261 1.611122555 -0.135863798 0.286456692 FBgn0015848 anon-10Ca anon-10Ca http://flybase.net/reports/FBgn0015848.html gene unnamed 16-Dec-15 2015_12 FBgn0015988 l(2)PC4-R lethal (2) PC4-R http://flybase.net/reports/FBgn0015988.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024945 NitFhit Nitrilase and fragile histidine triad fusion protein http://flybase.net/reports/FBgn0024945.html protein_coding_gene "0016810=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, 0047710=bis(5'-adenosyl)-triphosphatase activity, 0000257=nitrilase activity" 0006139=nucleobase-containing compound metabolic process "NitFlit, CG7067" "IPR003010=Carbon-nitrogen hydrolase, IPR001310=Histidine triad (HIT) protein, IPR019808=Histidine triad, conserved site, IPR011146=HIT-like domain" CG7067 16-Dec-15 2015_12 ENSDARG00000070116(nit1) YJL126W(NIT2) WBGene00003594(nft-1) ENSXETG00000012699(NIT1) ENSMUSG00000013997(Nit1) ENSG00000158793(NIT1) " embryonic stage && adult stage , embryonic stage "

ubiquitous viable FBgn0264269 CR43769 http://flybase.net/reports/FBgn0264269.html non_protein_coding_gene lincRNA.90 CR43769 16-Dec-15 2015_12 FBgn0026869 Thd1 Thd1 http://flybase.net/reports/FBgn0026869.html protein_coding_gene "0008263=pyrimidine-specific mismatch base pair DNA N-glycosylase activity, 0003690=double-stranded DNA binding" "0006298=mismatch repair, 0006974=cellular response to DNA damage stimulus, 0006289=nucleotide-excision repair" "1981, G/T-mismatch-specific-thymine-DNA-glycosylase, CG1981" "IPR017956=AT hook, DNA-binding motif, IPR005122=Uracil-DNA glycosylase-like, IPR015637=DNA glycosylase, G/T mismatch" CG1981 16-Dec-15 2015_12 viable DRSC17169 K -0.28320226 0.293171755 -0.071027591 0.110707399 1.084548863 1.81377038 FBgn0036843 CG6812 http://flybase.net/reports/FBgn0036843.html protein_coding_gene "0003677=DNA binding, 0015075=ion transmembrane transporter activity" "0006811=ion transport, 0055085=transmembrane transport, 0006281=DNA repair" 0016020=membrane "IPR004686=Tricarboxylate/iron carrier, IPR003583=Helix-hairpin-helix DNA-binding motif, class 1" CG6812 16-Dec-15 2015_12 "ENSDARG00000025515,ENSDARG00000017960(sfxn2)" YOR271C(FSF1) WBGene00015777(sfxn-2) ENSXETG00000015227(sfxn2) ENSMUSG00000025036(Sfxn2) ENSG00000156398(SFXN2) viable FBgn0069321 X-164-5 X-164-5 http://flybase.net/reports/FBgn0069321.html gene 16-Dec-15 2015_12 FBgn0024989 CG3777 http://flybase.net/reports/FBgn0024989.html FBgn0025695 protein_coding_gene "EG:125H10.1, CK01670, BEST:CK01670" CG3777 16-Dec-15 2015_12 "viable,fertile" DRSC18489 K 0.312320409 1.183998387 1.234336032 1.203018206 -1.599148653 -0.350455827 FBgn0266086 CR44828 http://flybase.net/reports/FBgn0266086.html non_protein_coding_gene CR44828 16-Dec-15 2015_12 FBgn0065194 l(2)SH2325 lethal (2) SH2325 http://flybase.net/reports/FBgn0065194.html gene l(2)SH2 2325 16-Dec-15 2015_12 "lethal,recessive" FBgn0054003 NimB3 Nimrod B3 http://flybase.net/reports/FBgn0054003.html FBgn0082871 protein_coding_gene 0042742=defense response to bacterium 0005576=extracellular region "CG34003, CG16882, BP1035, nimrod B3, unnamed, NimB3, nimB3" IPR000742=EGF-like domain CG34003 16-Dec-15 2015_12 FBgn0013275 Hsp70Aa Heat-shock-protein-70Aa http://flybase.net/reports/FBgn0013275.html "FBgn0001231, FBgn0051366" protein_coding_gene "0035080=heat shock-mediated polytene chromosome puffing, 0001666=response to hypoxia, 0009408=response to heat" 0005875=microtubule associated complex "Protein 70, Hsp-70, hsp70a, dhsp70, Hsp70a, Heat shock protein-70, HSP70, 87A, hsp70 Aa, hsp-70, Hsp70A, heat shock 70, dHsp70, hsp70Aa, hsp70A, CG31366, Hsp 70, Dm-hsp70, Hsp70, DmHSP70AA, hs70, dhsp70Aa, hsp 70, hsp70 87A, 87A locus, heat-shock protein 70, Hsp-70Aa, hsp70, hsp70(87A)" "IPR013126=Heat shock protein 70 family, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site" CG31366 16-Dec-15 2015_12 "lethal,viable,fertile" DRSC21246 IEK 0.234830516 -2.273098897 -1.685379565 -1.340837156 0.087446517 1.996683836 FBgn0034795 MED23 Mediator complex subunit 23 http://flybase.net/reports/FBgn0034795.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex" "dSUR2, CG3695, Gal11/SUR2, Med23, MED23, Trap150, Trap150beta, dTRAP150beta" "IPR021629=Mediator complex, subunit Med23" CG3695 16-Dec-15 2015_12 ENSDARG00000029157(med23) WBGene00006349(sur-2) ENSXETG00000008243(MED23) ENSMUSG00000019984(Med23) ENSG00000112282(MED23) viable FBgn0263132 Cht6 Cht6 http://flybase.net/reports/FBgn0263132.html "FBgn0030171, FBgn0030172, FBgn0030173" protein_coding_gene "0004568=chitinase activity, 0008061=chitin binding" "0006032=chitin catabolic process, 0005975=carbohydrate metabolic process" 0005576=extracellular region "CG2989, CT5624, CG15314, CG43374, CG15313" "IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR002557=Chitin binding domain, IPR017853=Glycoside hydrolase superfamily, IPR001579=Glycoside hydrolase, chitinase active site, IPR029070=Chitinase insertion domain" CG43374 16-Dec-15 2015_12 FBgn0044874 E(Mer)IIIa E(Mer)IIIa http://flybase.net/reports/FBgn0044874.html gene Group IIIa 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,visible,dominant" wing vein L5 FBgn0060457 l(3)S117913 lethal (3) S117913 http://flybase.net/reports/FBgn0060457.html gene 1179/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0032480 Edem2 "ER degradation enhancer, mannosidase alpha-like 2" http://flybase.net/reports/FBgn0032480.html protein_coding_gene "0005509=calcium ion binding, 0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, 0051082=unfolded protein binding" "0030433=ER-associated ubiquitin-dependent protein catabolic process, 0030968=endoplasmic reticulum unfolded protein response" 0016020=membrane "CG5682, EDEM2, edem2, Edem2" "IPR003137=PA domain, IPR001382=Glycoside hydrolase, family 47" CG5682 16-Dec-15 2015_12 ENSDARG00000010524 WBGene00013919(ZC506.1) ENSXETG00000004541(EDEM3) ENSMUSG00000043019(Edem3) ENSG00000116406(EDEM3) viable DRSC02877 E 0.409168354 0.287296474 -2.375067372 0.798823179 0.139725863 -0.86745841 FBgn0051413 CG31413 http://flybase.net/reports/FBgn0051413.html FBgn0039105 protein_coding_gene 0016971=flavin-linked sulfhydryl oxidase activity "0045454=cell redox homeostasis, 0055114=oxidation-reduction process, 0032504=multicellular organism reproduction" 0005615=extracellular space CG10299 "IPR017905=ERV/ALR sulfhydryl oxidase domain, IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG31413 16-Dec-15 2015_12 FBgn0013445 fout fade out http://flybase.net/reports/FBgn0013445.html gene 0007625=grooming behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0003969 vap vacuolar peduncle http://flybase.net/reports/FBgn0003969.html FBgn0020383 protein_coding_gene 0005096=GTPase activator activity "0043547=positive regulation of GTPase activity, 0040008=regulation of growth, 0030100=regulation of endocytosis, 0046580=negative regulation of Ras protein signal transduction, 0016319=mushroom body development, 0048149=behavioral response to ethanol" "0031235=intrinsic component of the cytoplasmic side of the plasma membrane, 0005737=cytoplasm" "CG9209, p120RasGAP, vacuolar pedunculi, RasGAP/Vap, rasGap, RasGap, RAS-GAP, Ras GTPase-activating protein, D-RasGAP, RasGAP, vacuolar peduncule" "IPR000980=SH2 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000008=C2 domain, IPR023152=Ras GTPase-activating protein, conserved site, IPR001849=Pleckstrin homology domain, IPR001936=Ras GTPase-activating protein, IPR001452=SH3 domain, IPR008936=Rho GTPase activation protein" CG9209 16-Dec-15 2015_12 ENSDARG00000035535(rasa1) WBGene00021238(gap-3) ENSXETG00000011717(RASA1) ENSMUSG00000021549(Rasa1) ENSG00000145715(RASA1) embryonic stage -- adult stage "viable,fertile,short lived,recessive,neuroanatomy defective,visible" "adult brain,ellipsoid body,nodulus,neuron & adult brain,lysosome & neuron & adult brain,autophagic vacuole & neuron & adult brain,optic lobe,wing" FBgn0082345 HM501 HM501 http://flybase.net/reports/FBgn0082345.html gene 16-Dec-15 2015_12 FBgn0085821 CR41612 http://flybase.net/reports/FBgn0085821.html FBan0041612 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0085217 CG34188 http://flybase.net/reports/FBgn0085217.html protein_coding_gene CG34188 16-Dec-15 2015_12 FBgn0036871 CG14096 http://flybase.net/reports/FBgn0036871.html protein_coding_gene CG14096 16-Dec-15 2015_12 FBgn0001585 l(1)carot2 lethal (1) carot2 http://flybase.net/reports/FBgn0001585.html gene l(1)5 16-Dec-15 2015_12 lethal FBgn0034427 CG10474 http://flybase.net/reports/FBgn0034427.html protein_coding_gene 0003948=N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity "IPR000246=Peptidase T2, asparaginase 2, IPR029055=Nucleophile aminohydrolases, N-terminal" CG10474 16-Dec-15 2015_12 ENSDARG00000004889 WBGene00019867(R04B3.2) ENSXETG00000009427(AGA) ENSMUSG00000031521(Aga) ENSG00000038002(AGA) viable DRSC05993 K -0.310741477 1.024861685 -0.080854886 0.768602311 0.315750793 1.652017327 FBgn0263538 mir-4965 mir-4965 stem loop http://flybase.net/reports/FBgn0263538.html miRNA_gene "dme-mir-4965, CR43523" CR43523 16-Dec-15 2015_12 FBgn0037230 CG9780 http://flybase.net/reports/FBgn0037230.html FBan0009780 protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis Neprilysin "IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13, IPR024079=Metallopeptidase, catalytic domain" CG9780 16-Dec-15 2015_12 viable DRSC12333 I 2.158099171 0.690104653 -0.087531775 0.332305369 -0.219201597 0.651107935 FBgn0029729 CG12682 http://flybase.net/reports/FBgn0029729.html protein_coding_gene "IPR015880=Zinc finger, C2H2-like" CG12682 16-Dec-15 2015_12 viable FBgn0005066 fs(2)OW206 female sterile (2) OW206 http://flybase.net/reports/FBgn0005066.html gene 16-Dec-15 2015_12 FBgn0020446 E-1a E-1a http://flybase.net/reports/FBgn0020446.html gene 0007520=myoblast fusion 16-Dec-15 2015_12 somatic muscle FBgn0002408 l(3)99Di lethal (3) 99Di http://flybase.net/reports/FBgn0002408.html gene 16-Dec-15 2015_12 lethal FBgn0283458 EC3-13 Enhancer of CCT 3-13 http://flybase.net/reports/FBgn0283458.html gene 16-Dec-15 2015_12 FBgn0066131 E(sda)B E(sda)B http://flybase.net/reports/FBgn0066131.html gene Line B 16-Dec-15 2015_12 FBgn0263582 CR43607 http://flybase.net/reports/FBgn0263582.html non_protein_coding_gene CR43607 16-Dec-15 2015_12 FBgn0028218 l(3)S007934 lethal (3) S007934 http://flybase.net/reports/FBgn0028218.html gene "0079/34, 1175/05, l(3)s007934, 0363/02" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264279 Su(Mir)1A4-1 http://flybase.net/reports/FBgn0264279.html gene 16-Dec-15 2015_12 FBgn0001578 l(1)air16 lethal aberrant immune response 16 http://flybase.net/reports/FBgn0001578.html gene air16 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,melanotic mass phenotype,lethal,polyphasic" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland,embryonic/larval hindgut,ring gland,gastric caecum,embryonic/larval salivary gland,garland cell" FBgn0035703 CG8270 http://flybase.net/reports/FBgn0035703.html protein_coding_gene "IPR009755=Colon cancer-associated Mic1-like, IPR015943=WD40/YVTN repeat-like-containing domain" CG8270 16-Dec-15 2015_12 ENSDARG00000029307(zgc:101800) WBGene00021738(Y50D4A.4) ENSMUSG00000024410(3110002H16Rik) ENSG00000141452(C18orf8) viable FBgn0082681 E(ftz)3201 E(ftz)3201 http://flybase.net/reports/FBgn0082681.html gene 3201 16-Dec-15 2015_12 FBgn0042083 CG3267 http://flybase.net/reports/FBgn0042083.html protein_coding_gene "0004485=methylcrotonoyl-CoA carboxylase activity, 0004658=propionyl-CoA carboxylase activity, 0016421=CoA carboxylase activity" "0009087=methionine catabolic process, 0006567=threonine catabolic process, 0006551=leucine metabolic process, 0006550=isoleucine catabolic process, 0007563=regulation of eclosion, 0006574=valine catabolic process, 0009062=fatty acid catabolic process" 0005759=mitochondrial matrix "MCCC2_DROME, FBgn0042083, l(2)4524" "IPR029045=ClpP/crotonase-like domain, IPR011762=Acetyl-coenzyme A carboxyltransferase, N-terminal, IPR000022=Carboxyl transferase, IPR011763=Acetyl-coenzyme A carboxyltransferase, C-terminal" CG3267 16-Dec-15 2015_12 ENSDARG00000017571(mccc2) WBGene00008514(F02A9.4) ENSXETG00000018213(mccc2) ENSMUSG00000021646(Mccc2) ENSG00000131844(MCCC2) "partially lethal - majority die,lethal,recessive,viable" FBgn0024218 l(2)39Ea lethal (2) 39Ea http://flybase.net/reports/FBgn0024218.html gene 16-Dec-15 2015_12 lethal FBgn0266956 CR45407 http://flybase.net/reports/FBgn0266956.html non_protein_coding_gene CR45407 16-Dec-15 2015_12 FBgn0058313 CG40313 http://flybase.net/reports/FBgn0058313.html FBan0040313 protein_coding_gene 16-Dec-15 2015_12 FBgn0015914 bk27 bk27 http://flybase.net/reports/FBgn0015914.html gene 16-Dec-15 2015_12 FBgn0070057 11 11 http://flybase.net/reports/FBgn0070057.html gene 0001754=eye photoreceptor cell differentiation #1 16-Dec-15 2015_12 FBgn0001270 irreA irregular optic chiasma A http://flybase.net/reports/FBgn0001270.html gene 16-Dec-15 2015_12 FBgn0037541 CG2747 http://flybase.net/reports/FBgn0037541.html protein_coding_gene 0022008=neurogenesis "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG2747 16-Dec-15 2015_12 "ENSDARG00000059116(LOC571772),ENSDARG00000023999(heatr5a)" WBGene00015743(C13F10.4) ENSXETG00000014133(HEATR5A) "ENSMUSG00000039414(Heatr5b),ENSMUSG00000035181(Heatr5a)" "ENSG00000008869(HEATR5B),ENSG00000129493(HEATR5A)" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0060439 l(3)S124802a lethal (3) S124802a http://flybase.net/reports/FBgn0060439.html gene 1248/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0065898 l(2)SH0204 lethal (2) SH0204 http://flybase.net/reports/FBgn0065898.html gene l(2)SH2 0204 16-Dec-15 2015_12 "lethal,recessive" FBgn0259149 CG42264 http://flybase.net/reports/FBgn0259149.html "FBgn0029806, FBgn0029805" protein_coding_gene "0004180=carboxypeptidase activity, 0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" "0046331=lateral inhibition, 0006508=proteolysis" "CG15769, CG15768" "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG42264 16-Dec-15 2015_12 YHR132C(ECM14) FBgn0028747 E(E2f)2B E(E2f)2B http://flybase.net/reports/FBgn0028747.html gene E(E2F)2B 16-Dec-15 2015_12 FBgn0065276 l(2)SH2046 lethal (2) SH2046 http://flybase.net/reports/FBgn0065276.html gene l(2)SH2 2046 16-Dec-15 2015_12 "lethal,recessive" FBgn0014346 ms(2)916 male sterile (2) 916 http://flybase.net/reports/FBgn0014346.html gene 16-Dec-15 2015_12 testis FBgn0038462 CG17556 http://flybase.net/reports/FBgn0038462.html protein_coding_gene 0005875=microtubule associated complex "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG17556 16-Dec-15 2015_12 ENSDARG00000003308 YJR088C(EMC2) WBGene00021973(Y57G7A.10) ENSXETG00000003604(TEgg055h07.1) ENSMUSG00000022337(Ttc35) ENSG00000104412(TTC35) FBgn0002133 l(2)K208 lethal (2) K208 http://flybase.net/reports/FBgn0002133.html gene 16-Dec-15 2015_12 lethal FBgn0083242 EP1244 EP1244 http://flybase.net/reports/FBgn0083242.html gene 16-Dec-15 2015_12 FBgn0030792 CG4789 http://flybase.net/reports/FBgn0030792.html protein_coding_gene 0005525=GTP binding 0007264=small GTPase mediated signal transduction Q9VXA9 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily" CG4789 16-Dec-15 2015_12 ENSDARG00000040959(rabl3) WBGene00013790(Y116A8C.10) ENSMUSG00000022827(Rabl3) ENSG00000144840(RABL3) viable FBgn0020429 GluRIIB Glutamate receptor IIB http://flybase.net/reports/FBgn0020429.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity, 0008066=glutamate receptor activity, 0004970=ionotropic glutamate receptor activity" "0060025=regulation of synaptic activity, 0035249=synaptic transmission, glutamatergic, 0006811=ion transport, 0007274=neuromuscular synaptic transmission, 0030510=regulation of BMP signaling pathway" "0031594=neuromuscular junction, 0097482=muscle cell postsynaptic density, 0008328=ionotropic glutamate receptor complex, 0005886=plasma membrane, 0045211=postsynaptic membrane" "DmelGluRIIB, GluRIIb, glutamate receptor, unnamed, CG7234, dglurIIB, DGluIIB, dGluRIIB, Glu-RIIB, DGluRIIB, glurIIB, glutamate receptor IIB, DGluR-IIB" "IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region, IPR001508=Ionotropic glutamate receptor, metazoa, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor" CG7234 16-Dec-15 2015_12 embryonic stage | stage 17 larval neuromuscular junction

"wild-type,neurophysiology defective,neuroanatomy defective,viable" "neuromuscular junction,neuromuscular junction | larval stage,neuromuscular junction | larval stageMhc.PW,neuromuscular junctionMhc.PW,neuromuscular junctionhow-24B" FBgn0264516 CG43915 http://flybase.net/reports/FBgn0264516.html protein_coding_gene 0016021=integral component of membrane CG43915 16-Dec-15 2015_12 FBgn0034776 CG13527 http://flybase.net/reports/FBgn0034776.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH182 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG13527 16-Dec-15 2015_12 viable FBgn0020376 Sr-CIII "Scavenger receptor class C, type III" http://flybase.net/reports/FBgn0020376.html FBgn0051962 protein_coding_gene 0005044=scavenger receptor activity 0016020=membrane "Scavenger Receptor, dSR-CIII, CG31962, SR-CIII" "IPR000436=Sushi/SCR/CCP domain, IPR000998=MAM domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG31962 16-Dec-15 2015_12 "ENSDARG00000068475,ENSDARG00000024017" "viable,tumorigenic" DRSC22262 K -0.277835385 0.362907379 -0.03892982 0.238862749 -1.870850254 -1.181891372 FBgn0085399 CG34370 http://flybase.net/reports/FBgn0085399.html "FBgn0082869, FBgn0034680, FBgn0050405, FBgn0054004, FBgn0034678, FBgn0034679, FBgn0050408, FBgn0053227" protein_coding_gene "BP1037, unnamed, CG33227, CG30405, CG13499, CG34004, CT32866, CG13497, CG13498, CG30408, tld-like" "IPR000859=CUB domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat" CG34370 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0038069 CG11608 http://flybase.net/reports/FBgn0038069.html protein_coding_gene 0004806=triglyceride lipase activity "0032504=multicellular organism reproduction, 0006629=lipid metabolic process" 0005615=extracellular space "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG11608 16-Dec-15 2015_12 "YLR020C(YEH2),YLL012W(YEH1)" viable DRSC14334 K 0.62264917 -0.03912048 0.121043963 0.1225708 -0.720828306 1.988500645 FBgn0034382 CG18609 http://flybase.net/reports/FBgn0034382.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane CT42569 IPR002076=ELO family CG18609 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0035999 CG3552 http://flybase.net/reports/FBgn0035999.html protein_coding_gene 0080048=GDP-D-glucose phosphorylase activity "IPR026506=GDP-L-galactose/GDP-D-glucose phosphorylase, IPR011146=HIT-like domain" CG3552 16-Dec-15 2015_12 ENSDARG00000062760(LOC100332718) WBGene00015678(C10F3.4) ENSXETG00000012962(C15orf58) ENSMUSG00000050973(D330012F22Rik) ENSG00000183208 viable FBgn0082580 tym thyme http://flybase.net/reports/FBgn0082580.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 dendrite FBgn0029589 CG14810 http://flybase.net/reports/FBgn0029589.html protein_coding_gene CG14810 16-Dec-15 2015_12 viable DRSC17693 I -1.040430477 2.424301473 0.432929002 -0.483397433 -0.898744332 0.21346334 FBgn0262518 Rab8 Rab8 http://flybase.net/reports/FBgn0262518.html "FBgn0015796, FBgn0084975" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0015031=protein transport, 0008582=regulation of synaptic growth at neuromuscular junction, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport" "0043025=neuronal cell body, 0008021=synaptic vesicle, 0045202=synapse, 0055037=recycling endosome, 0031982=vesicle" "l(3)76BDu, Rab-r8, AAF49101, CG8287, O18338, rab8, dm-Rab8, Dm Rab8, DRAB8, DmRab8, Rab-protein 8, DRab8" "IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8287 16-Dec-15 2015_12 ENSDARG00000068628(rab8b) YFL005W(SEC4) WBGene00004272(rab-8) "ENSXETG00000008740(RAB8A),ENSXETG00000009721(RAB8B)" "ENSMUSG00000036943(Rab8b),ENSMUSG00000003037(Rab8a)" "ENSG00000167461(RAB8A),ENSG00000166128(RAB8B)" FBgn0039079 Ir94g Ionotropic receptor 94g http://flybase.net/reports/FBgn0039079.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "DmelIR94g, ionotropic receptor 94g, IR94g, CG17381" CG17381 16-Dec-15 2015_12 viable FBgn0266688 CR45178 http://flybase.net/reports/FBgn0266688.html non_protein_coding_gene CR45178 16-Dec-15 2015_12 FBgn0001153 giantoid giantoid http://flybase.net/reports/FBgn0001153.html gene gtd 16-Dec-15 2015_12 "visible,viable,reduced" adult head FBgn0084829 l(3)S023708 l(3)S023708 http://flybase.net/reports/FBgn0084829.html gene 16-Dec-15 2015_12 FBgn0086687 Desat1 Desaturase 1 http://flybase.net/reports/FBgn0086687.html "FBgn0023016, FBgn0061714, FBgn0061710, FBgn0043785, FBgn0017619, FBgn0043044" protein_coding_gene 0004768=stearoyl-CoA 9-desaturase activity "0042593=glucose homeostasis, 0019216=regulation of lipid metabolic process, 0006723=cuticle hydrocarbon biosynthetic process, 0042811=pheromone biosynthetic process, 0042594=response to starvation, 0009744=response to sucrose, 0055114=oxidation-reduction process, 0060179=male mating behavior, 0045572=positive regulation of imaginal disc growth, 0070328=triglyceride homeostasis, 0006633=fatty acid biosynthetic process, 0040018=positive regulation of multicellular organism growth, 0048047=mating behavior, sex discrimination, 0045793=positive regulation of cell size, 0010506=regulation of autophagy" "0016021=integral component of membrane, 0005783=endoplasmic reticulum, 0005811=lipid particle, 0031410=cytoplasmic vesicle" "fad, desaturase1, unnamed, desat1, Desat1, desat, anon-WO0118547.726, lethal (3) S028813, Fad, Fatty acid desaturase, Stearoyl CoA desaturase, CG5887, stearoyl-CoA 9-desaturase, l(3)S028813, desaturase 1, anon-WO0118547.730, desaturase, ds1, BEST:SD05462, fatty acid desaturase" "IPR015876=Fatty acid desaturase, type 1, core, IPR009160=Acyl-CoA desaturase, haem/steroid binding domain-containing, IPR005804=Fatty acid desaturase domain" CG5887 16-Dec-15 2015_12 "ENSDARG00000033662(scd),ENSDARG00000030265(scdb)" YGL055W(OLE1) "WBGene00001398(fat-6),WBGene00001399(fat-7),WBGene00001397(fat-5)" ENSXETG00000023757(BC096632.1) "ENSMUSG00000037071(Scd1),ENSMUSG00000025203(Scd2),ENSMUSG00000025202(Scd3),ENSMUSG00000050195(Scd4)" "ENSG00000099194(SCD),ENSG00000145284(SCD5)" DRSC16668 IEK -0.173004436 -1.876243832 0.328621657 -3.181107084 -5.590737184 -3.234440361 FBgn0264674 CR43959 http://flybase.net/reports/FBgn0264674.html non_protein_coding_gene CR43959 16-Dec-15 2015_12 FBgn0060354 l(3)S141710a lethal (3) S141710a http://flybase.net/reports/FBgn0060354.html gene 1417/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0039936 CG11148 http://flybase.net/reports/FBgn0039936.html protein_coding_gene "0005813=centrosome, 0072686=mitotic spindle" IPR003169=GYF domain CG11148 16-Dec-15 2015_12 ENSDARG00000009735(zgc:111944) "YPL105C(SYH1),YBR172C(SMY2)" WBGene00016002(C18H9.3) "ENSMUSG00000029714(Gigyf1),ENSMUSG00000048000(Gigyf2)" "ENSG00000146830(GIGYF1),ENSG00000204120(GIGYF2)" viable DRSC28907 K -0.005465446 -0.019092797 -0.027287401 0.043405609 2.418090207 1.828460345 FBgn0003878 tu(2)bw tumor (2) brown http://flybase.net/reports/FBgn0003878.html gene "mt[A], melanotic tumor A" 16-Dec-15 2015_12 "melanotic mass phenotype,viable,fertile" "thorax,head" FBgn0060662 l(3)S081610b lethal (3) S081610b http://flybase.net/reports/FBgn0060662.html gene 0816/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0051578 tRNA:CR31578 transfer RNA:CR31578 http://flybase.net/reports/FBgn0051578.html FBgn0060112 tRNA_gene 0033423=CCA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3R.trna20-ProTGG, CR31578, tRNA:P:TGG:AE002708-c, AE002708.trna14-ProTGG" CR31578 16-Dec-15 2015_12 FBgn0032021 CG7781 http://flybase.net/reports/FBgn0032021.html protein_coding_gene CG7781 16-Dec-15 2015_12 "WBGene00009399(F35C5.11),WBGene00017880(F28A12.3)" DRSC03068 K -1.0851981 -0.389909414 -0.511481237 0.317317805 -1.68037549 0.048809598 FBgn0001638 l(1)dn18 lethal (1) discs normal 18 http://flybase.net/reports/FBgn0001638.html gene l(1)d.norm.-18 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0063396 Stalker2\ORF3 ORF3 http://flybase.net/reports/FBgn0063396.html transposable_element_gene rom\ORF3 16-Dec-15 2015_12 FBgn0058392 CG40392 http://flybase.net/reports/FBgn0058392.html FBan0040392 protein_coding_gene 16-Dec-15 2015_12 FBgn0050062 CG30062 http://flybase.net/reports/FBgn0050062.html protein_coding_gene 0003796=lysozyme activity "IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR023346=Lysozyme-like domain, IPR001916=Glycoside hydrolase, family 22, IPR019799=Glycoside hydrolase, family 22, conserved site" CG30062 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" viable FBgn0062586 Mod(var)1658 Mod(var)1658 http://flybase.net/reports/FBgn0062586.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1658 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0083989 snoRNA:Me28S-C3420b snoRNA:Me28S-C3420b http://flybase.net/reports/FBgn0083989.html snoRNA_gene "CR34153, Me28S-C3420b, chr2R:7715032..7715192" CR34153 16-Dec-15 2015_12 FBgn0022013 l(2)k09104 lethal (2) k09104 http://flybase.net/reports/FBgn0022013.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033121 Cyp6u1 Cyp6u1 http://flybase.net/reports/FBgn0033121.html protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG3567, cytochrome P450, 6u1" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG3567 16-Dec-15 2015_12 YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" viable FBgn0038134 wntD wnt inhibitor of Dorsal http://flybase.net/reports/FBgn0038134.html protein_coding_gene "0001664=G-protein coupled receptor binding, 0005109=frizzled binding" "0009952=anterior/posterior pattern specification, 0016055=Wnt signaling pathway, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045995=regulation of embryonic development, 0007492=endoderm development, 0007370=ventral furrow formation, 0009798=axis specification, 0007280=pole cell migration, 0060070=canonical Wnt signaling pathway, 0050830=defense response to Gram-positive bacterium" "0005576=extracellular region, 0005578=proteinaceous extracellular matrix, 0005615=extracellular space, 0005886=plasma membrane" "WntD, wnt8, CG8458, Dm DWnt8, DWnt8, DWnt-8, Wnt inhibitor of Dorsal, Wnt8" "IPR026540=Wnt inhibitor of Dorsal protein, IPR005817=Wnt" CG8458 16-Dec-15 2015_12 "viable,immune response defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,maternal effect" "germline cell,embryo,ventral,ventral furrow,mesoderm" FBgn0262576 CG43116 http://flybase.net/reports/FBgn0262576.html protein_coding_gene CG43116 16-Dec-15 2015_12 FBgn0085684 CG41553 http://flybase.net/reports/FBgn0085684.html FBan0041553 protein_coding_gene 16-Dec-15 2015_12 FBgn0261555 CG42673 http://flybase.net/reports/FBgn0261555.html "FBgn0052048, FBgn0036011, FBgn0036012, FBgn0040825, FBgn0061389, FBgn0064857, FBgn0085301" protein_coding_gene "CG32048, CG17357, CG3179, CG14178, CG34272, Dm_3L:44995, BcDNA:RE71585, BcDNA:RE71517" "IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG42673 16-Dec-15 2015_12 DRSC10264 IK 0.310665047 1.820913291 0.829345832 0.319038732 1.820223427 -0.188356491 FBgn0032698 CG10336 http://flybase.net/reports/FBgn0032698.html protein_coding_gene "0000076=DNA replication checkpoint, 0008284=positive regulation of cell proliferation, 0048478=replication fork protection, 0031573=intra-S DNA damage checkpoint" "0005634=nucleus, 0000790=nuclear chromatin" IPR012923=Replication fork protection component Swi3 CG10336 16-Dec-15 2015_12 ENSDARG00000036136(tipin) WBGene00017738(F23C8.9) ENSXETG00000024752(TIPIN) ENSMUSG00000032397(Tipin) "viable,fertile" FBgn0067777 era errance http://flybase.net/reports/FBgn0067777.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 "egg,germline clone,oocyte nucleus,egg chamber" FBgn0263377 CR43429 http://flybase.net/reports/FBgn0263377.html non_protein_coding_gene CR43429 16-Dec-15 2015_12 FBgn0028909 tRNA:Q:34E tRNA:Q:34E http://flybase.net/reports/FBgn0028909.html "FBgn0051838, FBgn0060103" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033428=CAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:Q:CTG:AE002690, tRNA:gln, BG:DS01514.1, chr2L.trna28-GlnCTG, AE002690.trna19-GlnCTG, CR31838" CR31838 16-Dec-15 2015_12 FBgn0065679 l(2)SH0670 lethal (2) SH0670 http://flybase.net/reports/FBgn0065679.html gene l(2)SH2 0670 16-Dec-15 2015_12 "lethal,recessive" FBgn0259188 Ir7f Ionotropic receptor 7f http://flybase.net/reports/FBgn0259188.html "FBan0015327, FBgn0029967" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 7f, CG15327, DmelIR7f, CG42292, IR7f" CG42292 16-Dec-15 2015_12 viable FBgn0052798 CG32798 http://flybase.net/reports/FBgn0052798.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035380 CG9970 http://flybase.net/reports/FBgn0035380.html protein_coding_gene IPR011705=BTB/Kelch-associated CG9970 16-Dec-15 2015_12 viable FBgn0032919 CG9253 http://flybase.net/reports/FBgn0032919.html FBgn0025331 protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "anon-EST:GressD10, DmRH24, cg9253" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014014=RNA helicase, DEAD-box type, Q motif" CG9253 16-Dec-15 2015_12 YHR065C(RRP3) WBGene00012059(T26G10.1) ENSXETG00000022984(Q6P636_XENTR) ENSMUSG00000030204(Ddx47) ENSG00000213782(DDX47) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260500 Pkn::Rok http://flybase.net/reports/FBgn0260500.html engineered_fusion_gene "Rok-Pkn, Pkn::rok" 16-Dec-15 2015_12 FBgn0030063 CG1789 http://flybase.net/reports/FBgn0030063.html protein_coding_gene "0006364=rRNA processing, 0022008=neurogenesis, 0006412=translation" 0032040=small-subunit processome "IPR007144=Small-subunit processome, Utp11" CG1789 16-Dec-15 2015_12 ENSDARG00000039958(utp11l) YKL099C(UTP11) WBGene00007623(C16C10.2) "ENSXETG00000011509(),ENSXETG00000023077(utp11l)" ENSMUSG00000028907(Utp11l) ENSG00000183520(UTP11L) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0266141 CR44847 http://flybase.net/reports/FBgn0266141.html non_protein_coding_gene CR44847 16-Dec-15 2015_12 FBgn0027240 l(1)G0272 lethal (1) G0272 http://flybase.net/reports/FBgn0027240.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267861 Maf1 http://flybase.net/reports/FBgn0267861.html "FBan0040196, FBgn0058196, FBan0041604, FBgn0085814" protein_coding_gene 0016480=negative regulation of transcription from RNA polymerase III promoter "CG40196, dMaf1, CR41604" IPR015257=Repressor of RNA polymerase III transcription Maf1 CG40196 16-Dec-15 2015_12 "ENSDARG00000013122(maf1),ENSDARG00000036489(LOC100330993)" WBGene00016622(C43H8.2) ENSMUSG00000022553(Maf1) ENSG00000179632(MAF1) "developmental rate defective,large body" FBgn0259680 Pkcë« Protein kinase C ë« http://flybase.net/reports/FBgn0259680.html "FBgn0030387, FBgn0030388" protein_coding_gene "0004697=protein kinase C activity, 0019992=diacylglycerol binding, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0035556=intracellular signal transduction" 0005886=plasma membrane "PKCdelta, PKCd, CG11245, CG10524, CG42349, protein kinase C, protein kinase C delta, Pkcdelta, Protein kinase C delta" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR014376=Protein kinase C, delta/epsilon/eta/theta types, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR017441=Protein kinase, ATP binding site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR017892=Protein kinase, C-terminal, IPR020454=Diacylglycerol/phorbol-ester binding" CG42349 16-Dec-15 2015_12 YJL095W(BCK1) FBgn0085761 CR40642 http://flybase.net/reports/FBgn0085761.html FBan0040642 rRNA_gene CR40642 16-Dec-15 2015_12 FBgn0263697 Uba3 Ubiquitin activating enzyme 3 http://flybase.net/reports/FBgn0263697.html "FBgn0065282, FBgn0033882" protein_coding_gene "0019781=NEDD8 activating enzyme activity, 0016881=acid-amino acid ligase activity, 0005524=ATP binding" "0045879=negative regulation of smoothened signaling pathway, 0045116=protein neddylation" 0043234=protein complex "dUba3, human Uba3 homologue, CG13343, l(2)SH2 2028, lethal (2) SH2028, l(2)SH2028" "IPR023318=Ubiquitin activating enzyme, alpha domain, IPR014929=E2 binding, IPR018074=Ubiquitin-activating enzyme, E1, active site, IPR016040=NAD(P)-binding domain, IPR000594=THIF-type NAD/FAD binding fold" CG13343 16-Dec-15 2015_12 ENSDARG00000057987(uba3) YPR066W(UBA3) WBGene00004341(rfl-1) ENSXETG00000016167(UBA3) ENSMUSG00000030061(Uba3) ENSG00000144744(UBA3) "visible,partially lethal - majority die,some die during pupal stage,lethal,heat sensitive,recessive" "mesothoracic tergum,wing blade,heat sensitive" FBgn0036598 CG4982 http://flybase.net/reports/FBgn0036598.html protein_coding_gene 0022008=neurogenesis IPR007614=Retinin-like protein CG4982 16-Dec-15 2015_12 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0032247 CG5188 http://flybase.net/reports/FBgn0032247.html protein_coding_gene "0004177=aminopeptidase activity, 0008235=metalloexopeptidase activity" 0006508=proteolysis MAP1B "IPR000994=Peptidase M24, structural domain, IPR002467=Peptidase M24A, methionine aminopeptidase, subfamily 1, IPR001714=Peptidase M24, methionine aminopeptidase" CG5188 16-Dec-15 2015_12 ENSDARG00000019715(map1d) ENSXETG00000007534() ENSMUSG00000041921(Metapl1) ENSG00000172878(METAP1D) viable FBgn0263485 scaRNA:ë¬U2-55 small Cajal body-specific RNA : ë¬U2-55 http://flybase.net/reports/FBgn0263485.html snoRNA_gene "0030559=rRNA pseudouridylation guide activity, 0030565=snRNA pseudouridylation guide activity" 0015030=Cajal body "CR43600, chr2R:7677028..7677241, snoRNA:Prp8-a, snoRNA:Prp8, snoRNA:prp8-a, scaRNA:Prp8, pugU2-55" CR43600 16-Dec-15 2015_12 FBgn0030846 CG12992 http://flybase.net/reports/FBgn0030846.html protein_coding_gene CG12992 16-Dec-15 2015_12 viable FBgn0029969 CG10932 http://flybase.net/reports/FBgn0029969.html protein_coding_gene 0003985=acetyl-CoA C-acetyltransferase activity "0006090=pyruvate metabolic process, 0006633=fatty acid biosynthetic process, 0007052=mitotic spindle organization" "0005875=microtubule associated complex, 0005777=peroxisome, 0005739=mitochondrion, 0005811=lipid particle" 154229_at "IPR020613=Thiolase, conserved site, IPR020615=Thiolase, acyl-enzyme intermediate active site, IPR002155=Thiolase, IPR016039=Thiolase-like, IPR020616=Thiolase, N-terminal, IPR020617=Thiolase, C-terminal" CG10932 16-Dec-15 2015_12 YPL028W(ERG10) "WBGene00002183(kat-1),WBGene00020164(T02G5.4)" ENSXETG00000014477(acat1) ENSMUSG00000032047(Acat1) ENSG00000075239(ACAT1) "viable,fertile" FBgn0029944 Dok Downstream of kinase http://flybase.net/reports/FBgn0029944.html protein_coding_gene 0005158=insulin receptor binding "0046529=imaginal disc fusion, thorax closure, 0031098=stress-activated protein kinase signaling cascade, 0007394=dorsal closure, elongation of leading edge cells, 0007391=dorsal closure, 0007476=imaginal disc-derived wing morphogenesis" 0005938=cell cortex "CG2079, Ddok, l(1)G0331, lethal (1) G0331" "IPR002404=IRS-type PTB domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG2079 16-Dec-15 2015_12 "ENSXETG00000019047(DOK1),ENSXETG00000010545(DOK2)" "lethal,partially lethal - majority die,male,germline clone,rescuable maternal effect,cell shape defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heart primordium,thorax,chaeta,orbital bristle,interommatidial bristle,embryonic/first instar larval cuticle,dorsal,germline clone,rescuable maternal effect,embryonic leading edge cell & filamentous actin | germ-line clone" DRSC18204 I -0.704290753 -2.361072177 -0.076479879 -0.152288394 1.20745313 0.049122377 FBgn0023071 l(1)1Eg lethal (1) 1Eg http://flybase.net/reports/FBgn0023071.html gene "DCE-21, DCE-17" 16-Dec-15 2015_12 "lethal,recessive" FBgn0025815 Mcm6 Minichromosome maintenance 6 http://flybase.net/reports/FBgn0025815.html FBgn0000821 protein_coding_gene "0005524=ATP binding, 0003677=DNA binding, 0043138=3'-5' DNA helicase activity, 0003682=chromatin binding" "0006270=DNA replication initiation, 0046331=lateral inhibition, 0007307=eggshell chorion gene amplification, 0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0006260=DNA replication, 0048477=oogenesis" "0042555=MCM complex, 0005656=nuclear pre-replicative complex, 0005634=nucleus" "DmeMCM6, dMcm6, DmMCM6, female sterile(1)K1214, MCM6, McM6, CG4039, mcm6, fs(1)K1214" "IPR012340=Nucleic acid-binding, OB-fold, IPR018525=Mini-chromosome maintenance, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027925=MCM N-terminal domain, IPR031327=Mini-chromosome maintenance protein, IPR004039=Rubredoxin-type fold, IPR001208=MCM domain, IPR008049=DNA replication licensing factor Mcm6" CG4039 16-Dec-15 2015_12 "ENSDARG00000033231(mcm6l),ENSDARG00000057683(LOC100329673)" YGL201C(MCM6) WBGene00003158(mcm-6) "ENSXETG00000015671(TEgg078c13.1),ENSXETG00000014891(mcm6)" ENSMUSG00000026355(Mcm6) ENSG00000076003(MCM6) " egg stage | unfertilized egg , adult stage | female , embryonic stage | stage 11-12 , embryonic stage | 0-4 hr " " unfertilized egg

, embryonic central nervous system

" "viable,female sterile,lethal,recessive,small body,female sterile soma-dependent,reduced,wild-type,visible" "chorion,embryonic/larval brain,imaginal disc,egg,maternal effect,chorion | maternal effect,dorsal appendage,chaeta" FBgn0085570 CR41243 http://flybase.net/reports/FBgn0085570.html FBan0041243 pseudogene_attribute CG41243 CR41243 16-Dec-15 2015_12 FBgn0044114 E(rst)C162 E(rst)C162 http://flybase.net/reports/FBgn0044114.html gene 0001745=compound eye morphogenesis C162 16-Dec-15 2015_12 FBgn0039537 CG5590 http://flybase.net/reports/FBgn0039537.html protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process "0005811=lipid particle, 0005875=microtubule associated complex, 0005777=peroxisome" "IPR003033=SCP2 sterol-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG5590 16-Dec-15 2015_12 ENSDARG00000002523(hsdl2) "WBGene00000970(dhs-6),WBGene00000981(dhs-18)" ENSXETG00000002228(hsdl2) ENSMUSG00000028383(Hsdl2) ENSG00000119471(HSDL2) "viable,visible" trichogen cell FBgn0031181 Ir20a Ionotropic receptor 20a http://flybase.net/reports/FBgn0031181.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "IR20a, CG14584, DmelIR20a, ionotropic receptor 20a" CG14584 16-Dec-15 2015_12 viable FBgn0261724 EC201 http://flybase.net/reports/FBgn0261724.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0260034 siren8 siren 8 http://flybase.net/reports/FBgn0260034.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0029092 ced-6 ced-6 http://flybase.net/reports/FBgn0029092.html FBgn0033414 protein_coding_gene 0005515=protein binding "0016322=neuron remodeling, 0043277=apoptotic cell clearance" "Ced-6, ced6, CG11804, dced-6, drCed-6, drced-6, dCed-6" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006020=PTB/PI domain" CG11804 16-Dec-15 2015_12 "ENSDARG00000001733(si:xx-35d8.1),ENSDARG00000057833(LOC100006392)" WBGene00000420(ced-6) ENSMUSG00000056870(Gulp1) ENSG00000144366(GULP1) "viable,fertile,neuroanatomy defective" "embryonic hemocyte,ensheathing neuropil associated glial cell,glial cell" FBgn0084667 l(3)S066607 l(3)S066607 http://flybase.net/reports/FBgn0084667.html gene 16-Dec-15 2015_12 FBgn0052009 CR32009 http://flybase.net/reports/FBgn0052009.html pseudogene_attribute CG32009 CR32009 16-Dec-15 2015_12 FBgn0069995 BG01799 BG01799 http://flybase.net/reports/FBgn0069995.html gene 16-Dec-15 2015_12 stress response defective FBgn0083243 EP1207 EP1207 http://flybase.net/reports/FBgn0083243.html gene 16-Dec-15 2015_12 FBgn0005318 nicked-eye nicked eye http://flybase.net/reports/FBgn0005318.html gene ne 16-Dec-15 2015_12 visible eye FBgn0002371 l(3)91Fc lethal (3) 91Fc http://flybase.net/reports/FBgn0002371.html gene "l(DIX43)c5, l(3)BE61, l(3)C5, l(3)BE62, l(3)BE60, C5" 16-Dec-15 2015_12 lethal FBgn0266954 CR45405 http://flybase.net/reports/FBgn0266954.html non_protein_coding_gene CR45405 16-Dec-15 2015_12 FBgn0032160 CG4598 http://flybase.net/reports/FBgn0032160.html protein_coding_gene 0004165=dodecenoyl-CoA delta-isomerase activity 0008152=metabolic process 0005739=mitochondrion "IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily" CG4598 16-Dec-15 2015_12 ENSDARG00000018002 ENSXETG00000017302(dci) ENSMUSG00000024132(Dci) ENSG00000167969(ECI1) "viable,fertile" FBgn0060313 l(3)S147804 lethal (3) S147804 http://flybase.net/reports/FBgn0060313.html gene 1478/04 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051089 CG31089 http://flybase.net/reports/FBgn0051089.html FBgn0039388 protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process CG5990 "IPR029058=Alpha/Beta hydrolase fold, IPR025483=Lipase, eukaryotic, IPR006693=Partial AB-hydrolase lipase domain" CG31089 16-Dec-15 2015_12 YKL140W(TGL1) "WBGene00021963(Y57E12B.3),WBGene00010062(F54F3.3),WBGene00020016(R11G11.14),WBGene00022642(ZK6.7),WBGene00009773(F46B6.8)" ENSXETG00000009273(lipA) viable FBgn0022130 l(2)k06408 lethal (2) k06408 http://flybase.net/reports/FBgn0022130.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032615 CG6012 http://flybase.net/reports/FBgn0032615.html protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG6012 16-Dec-15 2015_12 FBgn0020798 nls nineless http://flybase.net/reports/FBgn0020798.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile,recessive" FBgn0040123 l(2)23CDe lethal (2) 23CDe http://flybase.net/reports/FBgn0040123.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033885 DJ-1ë± DJ-1ë± http://flybase.net/reports/FBgn0033885.html protein_coding_gene "0042775=mitochondrial ATP synthesis coupled electron transport, 0006979=response to oxidative stress, 0014065=phosphatidylinositol 3-kinase signaling, 0051896=regulation of protein kinase B signaling" "DJ-1, CG6646, DJ-1a, DJ-1alpha, DJ-1A" "IPR029062=Class I glutamine amidotransferase-like, IPR006287=DJ-1, IPR002818=DJ-1/PfpI" CG6646 16-Dec-15 2015_12 ENSDARG00000034826(park7) "WBGene00015184(djr-1.1),WBGene00016789(djr-1.2)" ENSXETG00000006018(park7) ENSMUSG00000028964(Park7) ENSG00000116288(PARK7) "stress response defective,short lived,locomotor behavior defective,viable,fertile,lethal,recessive,increased cell death,visible,chemical sensitive,lethal - all die before end of larval stage,some die during larval stage,chemical resistant" "eye,eye photoreceptor cell,ommatidium,dopaminergic neuron" FBgn0266223 CR44918 http://flybase.net/reports/FBgn0266223.html non_protein_coding_gene CR44918 16-Dec-15 2015_12 FBgn0060653 l(3)S083207 lethal (3) S083207 http://flybase.net/reports/FBgn0060653.html gene 0832/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0265861 CR44650 http://flybase.net/reports/FBgn0265861.html non_protein_coding_gene lincRNA.364 CR44650 16-Dec-15 2015_12 FBgn0032741 Sidpn similar to Deadpan http://flybase.net/reports/FBgn0032741.html protein_coding_gene "0003677=DNA binding, 0046983=protein dimerization activity" "0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG10446, side, Sidestep, Side, bHLHe51" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG10446 16-Dec-15 2015_12 viable FBgn0015847 akaal akaal http://flybase.net/reports/FBgn0015847.html gene 16-Dec-15 2015_12 "chemosensitive behavior defective,behavior defective" FBgn0085478 CG34449 http://flybase.net/reports/FBgn0085478.html "FBan0032705, FBgn0030129, FBgn0030128, FBgn0003058, FBgn0030127, FBgn0052705" protein_coding_gene 0008270=zinc ion binding "Dm_X:47283, p16, CG32705, CG12136, CG15372, pen16, anon-Pen16, Pen16, CG17251" "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG34449 16-Dec-15 2015_12 ENSDARG00000018508(zdhhc5) WBGene00012718(Y39E4B.7) "ENSXETG00000007463(zdhhc9),ENSXETG00000011225(ZDHHC14)" "ENSMUSG00000060166(Zdhhc8),ENSMUSG00000034075(Zdhhc5)" "ENSG00000099904(ZDHHC8),ENSG00000156599(ZDHHC5)" "viable,fertile" DRSC18044 IE -1.493607302 -4.337825011 -1.792982816 -3.015518462 -0.260090102 -0.679934595 FBgn0052207 CR32207 http://flybase.net/reports/FBgn0052207.html FBgn0063140 pseudogene_attribute "BcDNA:LD41276, hp-CR32207, CG32207" CR32207 16-Dec-15 2015_12 viable FBgn0040994 CR17567 http://flybase.net/reports/FBgn0040994.html "FBgn0044546, FBgn0063272" non_protein_coding_gene "BcDNA:GH05530, bs36b02.y1, anon-WO0140519.80, CG17567, bs35c03.y1" 16-Dec-15 2015_12 FBgn0004787 anon-h anon AT-rich sequence http://flybase.net/reports/FBgn0004787.html repeat_region 16-Dec-15 2015_12 FBgn0050011 gem gemini http://flybase.net/reports/FBgn0050011.html "FBgn0033488, FBgn0033489, FBgn0043524, FBgn0047234" protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "anon-AE003830.1, BcDNA:HL07889, CG30011, CG11867, unnamed, dCP2, persephone, CG3459" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR007604=CP2 transcription factor" CG30011 16-Dec-15 2015_12 "ENSDARG00000029497(tfcp2l1),ENSDARG00000060306(si:ch211-210c8.8),ENSDARG00000018000(si:ch211-207c15.3)" "ENSXETG00000009632(tfcp2),ENSXETG00000023707(Q5I078_XENTR)" "ENSMUSG00000009741(Ubp1),ENSMUSG00000009733(Tcfcp2),ENSMUSG00000026380(Tcfcp2l1)" "ENSG00000153560(UBP1),ENSG00000135457(TFCP2),ENSG00000115112(TFCP2L1)" "viable,fertile" FBgn0043574 S(faf)196 S(faf)196 http://flybase.net/reports/FBgn0043574.html gene 16-Dec-15 2015_12 FBgn0028140 l(3)S047916 lethal (3) S047916 http://flybase.net/reports/FBgn0028140.html gene 0479/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0267816 CR46141 http://flybase.net/reports/FBgn0267816.html non_protein_coding_gene CR46141 16-Dec-15 2015_12 FBgn0003100 PL(2)sp-G1 Polygenic locuis sternopleural G1 http://flybase.net/reports/FBgn0003100.html gene PL(2)sp[G1] 16-Dec-15 2015_12 FBgn0031011 CG8034 http://flybase.net/reports/FBgn0031011.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG8034 16-Dec-15 2015_12 DRSC20076 E -0.460834588 -0.852346825 1.197513651 -2.125196752 -0.009531845 0.057048702 FBgn0002482 l(3)SG41 lethal (3) SG41 http://flybase.net/reports/FBgn0002482.html FBgn0004723 gene "l(3)B9, l(3)ds9" 16-Dec-15 2015_12 "lethal,recessive" "imaginal disc,mitosis & nuclear chromosome" FBgn0060928 l(3)S042018 lethal (3) S042018 http://flybase.net/reports/FBgn0060928.html gene 0420/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0032010 CG8086 http://flybase.net/reports/FBgn0032010.html FBgn0032009 protein_coding_gene "0022008=neurogenesis, 0007605=sensory perception of sound" 0005643=nuclear pore CG8113 IPR010736=Sperm-tail PG-rich repeat CG8086 16-Dec-15 2015_12 "viable,fertile,auditory perception defective,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0267217 CR45657 http://flybase.net/reports/FBgn0267217.html non_protein_coding_gene CR45657 16-Dec-15 2015_12 FBgn0039177 CG13611 http://flybase.net/reports/FBgn0039177.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR002937=Amine oxidase CG13611 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC14614 E 0.341219879 0.06941403 1.7901796 -0.577721268 -0.439798134 -0.31191783 FBgn0002268 l(3)69Ag lethal (3) 69Ag http://flybase.net/reports/FBgn0002268.html gene "l(3)rsg30, rsg30, rose-gespleten region interval 30" 16-Dec-15 2015_12 FBgn0267714 CR46047 http://flybase.net/reports/FBgn0267714.html non_protein_coding_gene CR46047 16-Dec-15 2015_12 FBgn0037978 KLHL18 http://flybase.net/reports/FBgn0037978.html FBgn0062189 protein_coding_gene 0003779=actin binding "0046529=imaginal disc fusion, thorax closure" 0031463=Cul3-RING ubiquitin ligase complex "dKLHL18, anon-WO0118547.179, CG3571" "IPR011333=POZ domain, IPR011043=Galactose oxidase/kelch, beta-propeller, IPR015916=Galactose oxidase, beta-propeller, IPR000210=BTB/POZ domain, IPR030603=Kelch-like protein 18, IPR011705=BTB/Kelch-associated, IPR017096=BTB-kelch protein, IPR006652=Kelch repeat type 1" CG3571 16-Dec-15 2015_12 ENSDARG00000004306(klhl18) WBGene00002185(kel-3) ENSMUSG00000054792(Klhl18) ENSG00000114648(KLHL18) "viable,visible" "trichogen cell,scutellar bristle,adult external thorax,dorsal" DRSC26629 K -0.883204359 -0.451477481 -0.063146963 -0.716131096 1.633154256 0.321223323 FBgn0259267 C736 http://flybase.net/reports/FBgn0259267.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0086408 stl stall http://flybase.net/reports/FBgn0086408.html "FBgn0003529, FBgn0034778, FBgn0000946, FBgn0062482" protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0006508=proteolysis, 0001541=ovarian follicle development, 0030713=ovarian follicle cell stalk formation, 0048477=oogenesis" "fs(2)A16, CG3622, BcDNA:GM08694, stall, female sterile(2)A16" "IPR001590=Peptidase M12B, ADAM/reprolysin, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR024079=Metallopeptidase, catalytic domain" CG3622 16-Dec-15 2015_12 "WBGene00020567(T19D2.1),WBGene00000083(adt-2)" FBgn0034205 CG10950 http://flybase.net/reports/FBgn0034205.html protein_coding_gene 0008320=protein transmembrane transporter activity 0006606=protein import into nucleus "IPR013598=Exportin-1/Importin-beta-like, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG10950 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266472 hazelnut http://flybase.net/reports/FBgn0266472.html gene 16-Dec-15 2015_12 lethal "germline cyst,germline clone,oocyte,centrosome | germline clone" FBgn0035252 CG7970 http://flybase.net/reports/FBgn0035252.html FBgn0062131 protein_coding_gene "0016021=integral component of membrane, 0005829=cytosol" anon-WO0118547.268 IPR007248=Mpv17/PMP22 CG7970 16-Dec-15 2015_12 ENSDARG00000003144(zgc:92599) ENSXETG00000024780(BC077678.1-001) ENSMUSG00000029499(Pxmp2) ENSG00000176876 viable FBgn0033387 CG8008 http://flybase.net/reports/FBgn0033387.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8008 16-Dec-15 2015_12 ENSDARG00000026149(slc46a1) "WBGene00021159(Y4C6B.5),WBGene00009582(F40F9.5),WBGene00012811(Y43F8A.5)" ENSXETG00000023785(SLC46A1) "ENSMUSG00000020829(Slc46a1),ENSMUSG00000029650(Slc46a3)" "ENSG00000076351(SLC46A1),ENSG00000139508(SLC46A3)" "viable,fertile,visible" trichogen cell FBgn0030887 CG6867 http://flybase.net/reports/FBgn0030887.html protein_coding_gene "0008045=motor neuron axon guidance, 0016201=synaptic target inhibition" CT21241 "IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR008160=Collagen triple helix repeat, IPR003598=Immunoglobulin subtype 2, IPR003112=Olfactomedin-like domain" CG6867 16-Dec-15 2015_12 ENSDARG00000061576(colm) WBGene00000583(cof-2) ENSXETG00000020767(GLDN) ENSG00000186417(GLDN) viable FBgn0023057 l(1)2Ff lethal (1) 2Ff http://flybase.net/reports/FBgn0023057.html gene 1200E17a 16-Dec-15 2015_12 "lethal,recessive" FBgn0034315 CG5721 http://flybase.net/reports/FBgn0034315.html protein_coding_gene "IPR000225=Armadillo, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG5721 16-Dec-15 2015_12 ENSDARG00000060763 ENSXETG00000014338(armc6) ENSMUSG00000002343(Armc6) ENSG00000105676(ARMC6) viable FBgn0034592 CG9406 http://flybase.net/reports/FBgn0034592.html protein_coding_gene 0005509=calcium ion binding "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG9406 16-Dec-15 2015_12 ENSMUSG00000026495(Efcab2) viable DRSC04552 E -0.04549876 0.134993878 3.02212232 0.245069034 -0.077724851 -1.168799764 FBgn0004937 ABO-X Abnormal Ooycte on X http://flybase.net/reports/FBgn0004937.html region ABO 16-Dec-15 2015_12 FBgn0039102 SPE Spatzle-Processing Enzyme http://flybase.net/reports/FBgn0039102.html protein_coding_gene 0004252=serine-type endopeptidase activity "0031638=zymogen activation, 0050829=defense response to Gram-negative bacterium, 0006959=humoral immune response, 0006952=defense response, 0045087=innate immune response, 0009620=response to fungus, 0050832=defense response to fungus, 0050830=defense response to Gram-positive bacterium, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0045752=positive regulation of Toll signaling pathway, 0008063=Toll signaling pathway, 0006508=proteolysis" 0005576=extracellular region "spz processing enzyme, c-SP4, SP4, proPO-AE, CT37173, Spatzle-processing enzyme, Spz-processing enzyme, spe, CG16705, Sp4" "IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG16705 16-Dec-15 2015_12 "viable,partially lethal - majority live,heat sensitive,immune response defective,recessive,lethal,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval fat body,embryonic/larval hemocoel,trichogen cell" FBgn0261244 inaE inactivation no afterpotential E http://flybase.net/reports/FBgn0261244.html "FBgn0001264, FBgn0053174, FBgn0030523, FBgn0030526, FBgn0030527, FBgn0040866, FBgn0052630" protein_coding_gene 0004465=lipoprotein lipase activity "0007602=phototransduction, 0006979=response to oxidative stress, 0006629=lipid metabolic process" 0005737=cytoplasm "EP(X)1101, CG33174, CG11104, DAGL, CG32630, CG15761, CG11096, diacylglycerol lipase, CG11102" "IPR002921=Fungal lipase-like domain, IPR029058=Alpha/Beta hydrolase fold" CG33174 16-Dec-15 2015_12 ENSDARG00000062956(dagla) WBGene00018364(F42G9.6) ENSXETG00000006696(DAGLA) ENSMUSG00000035735(Dagla) ENSG00000134780(DAGLA) FBgn0260319 GSd312 http://flybase.net/reports/FBgn0260319.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0024507 33-13 33-13 http://flybase.net/reports/FBgn0024507.html gene 0003677=DNA binding 0005634=nucleus unnamed 16-Dec-15 2015_12 FBgn0033236 CG14764 http://flybase.net/reports/FBgn0033236.html FBgn0033239 protein_coding_gene CG2923 CG14764 16-Dec-15 2015_12 "WBGene00014235(ZK1225.1),WBGene00009614(F41D3.9),WBGene00011024(R05A10.7),WBGene00011783(T15D6.9),WBGene00014196(ZK1053.1),WBGene00017703(F22E5.1),WBGene00015860(C16D9.5),WBGene00015859(C16D9.4),WBGene00009228(F28G4.3),WBGene00007368(C06B8.2),WBGene00021565(Y45G12C.1),WBGene00018501(F46F5.10),WBGene00021298(Y27F2A.6),WBGene00009312(F32B4.1)" viable FBgn0031117 GstT3 Glutathione S transferase T3 http://flybase.net/reports/FBgn0031117.html protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "gstt3, GSTT3, CG1702, cg1702" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG1702 16-Dec-15 2015_12 "ENSDARG00000042428(gstt1a),ENSDARG00000017388(gstt1b)" "ENSXETG00000024924(BC087825.1),ENSXETG00000022358(TNeu058f17.1)" "ENSMUSG00000001663(Gstt1),ENSMUSG00000001665(Gstt3),ENSMUSG00000009093(Gstt4),ENSMUSG00000033318(Gstt2)" "ENSG00000184674(GSTT1),ENSG00000099984(GSTT2),ENSG00000133433(GSTT2B)" FBgn0005478 l(1)ts1081 lethal (1) ts1081 http://flybase.net/reports/FBgn0005478.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0065597 l(2)SH0882 lethal (2) SH0882 http://flybase.net/reports/FBgn0065597.html gene l(2)SH2 0882 16-Dec-15 2015_12 "lethal,recessive" FBgn0267148 CR45588 http://flybase.net/reports/FBgn0267148.html non_protein_coding_gene CR45588 16-Dec-15 2015_12 FBgn0264563 CG43935 http://flybase.net/reports/FBgn0264563.html protein_coding_gene CG43935 16-Dec-15 2015_12 FBgn0085526 CG40856 http://flybase.net/reports/FBgn0085526.html FBan0040856 protein_coding_gene 16-Dec-15 2015_12 FBgn0004084 ë±ë_-element ë±ë_ element http://flybase.net/reports/FBgn0004084.html non_protein_coding_gene "alpha-beta, alpha-gamma element, 0516/01, Hsralphagamma, Hsr alpha beta, alpha repeat element, alphabeta-element, 516/1, alpha-beta gene" 16-Dec-15 2015_12 "viable,partially lethal - majority die,recessive" FBgn0011245 ms(2)29F male sterile (2) 29F http://flybase.net/reports/FBgn0011245.html gene 0007286=spermatid development ms(2)07717 16-Dec-15 2015_12 "male sterile,recessive" FBgn0065053 snoRNA:Me18S-C1831 http://flybase.net/reports/FBgn0065053.html FBgn0053674 snoRNA_gene 0030555=RNA modification guide activity 0005730=nucleolus "Dm-737, Me18S-C1831(SnoR737), snoRNA:737, CR33674, snoR737" CR33674 16-Dec-15 2015_12 FBgn0000121 Arr2 Arrestin 2 http://flybase.net/reports/FBgn0000121.html protein_coding_gene "0005515=protein binding, 0002046=opsin binding" "0007602=phototransduction, 0016059=deactivation of rhodopsin mediated signaling, 0007605=sensory perception of sound, 0016062=adaptation of rhodopsin mediated signaling, 0016060=metarhodopsin inactivation, 0045494=photoreceptor cell maintenance" "0016029=subrhabdomeral cisterna, 0005737=cytoplasm, 0016028=rhabdomere" "49kD Arrestin homolog, 49, Phosrestin I, arrestin 2, Arrestin B, Arr, CG5962, ArrB-ml, Arr-2, PRI, Beta-Arrestin, ARR2, Arrestin-2, phosrestin-1, arrestin-like protein, ArrB, Arrestin2, arrestin, phosrestin I, AH, arr, arr2, arrestin-2, arrestin2, Dro.-Arr.II, DAII" "IPR017864=Arrestin, conserved site, IPR014756=Immunoglobulin E-set, IPR011022=Arrestin C-terminal-like domain, IPR011021=Arrestin-like, N-terminal, IPR014753=Arrestin, N-terminal, IPR000698=Arrestin, IPR014752=Arrestin, C-terminal" CG5962 16-Dec-15 2015_12 adult stage rhabdomere

"neurophysiology defective,wild-type,auditory perception defective,viable" "ommatidium,retina,rhabdomere,photoreceptor cell,eye photoreceptor cell,eye,conditional,rhabdomere | conditional" FBgn0036080 Or67d Odorant receptor 67d http://flybase.net/reports/FBgn0036080.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity, 0016503=pheromone receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007619=courtship behavior, 0007608=sensory perception of smell, 0043695=detection of pheromone, 0019236=response to pheromone" "0071683=sensory dendrite, 0032590=dendrite membrane, 0005929=cilium" "CG14157, OR67d, 67d, Or67d" "IPR004117=Olfactory receptor, Drosophila" CG14157 16-Dec-15 2015_12 "courtship behavior defective,neurophysiology defective,male,smell perception defective" "sensillum trichodeum of antennal segment 3,antennal trichoid sensillum at1" FBgn0001708 l(1)ESHS29 lethal (1) ESHS29 http://flybase.net/reports/FBgn0001708.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259376 EP-880 http://flybase.net/reports/FBgn0259376.html gene 16-Dec-15 2015_12 visible wing vein FBgn0085071 clh cliffhanger http://flybase.net/reports/FBgn0085071.html gene 0008344=adult locomotory behavior D44 16-Dec-15 2015_12 "locomotor behavior defective,recessive" FBgn0262478 CG43068 http://flybase.net/reports/FBgn0262478.html protein_coding_gene CG43068 16-Dec-15 2015_12 FBgn0010124 l(1)HM25 lethal (1) of Helen Mayo http://flybase.net/reports/FBgn0010124.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0040027 CG17452 http://flybase.net/reports/FBgn0040027.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035534 mRpS6 mitochondrial ribosomal protein S6 http://flybase.net/reports/FBgn0035534.html FBgn0047039 protein_coding_gene "0003735=structural constituent of ribosome, 0019843=rRNA binding" 0006412=translation 0005763=mitochondrial small ribosomal subunit "MRP-S6, CG15016, Mrps6, BcDNA:RH10862" "IPR000529=Ribosomal protein S6, IPR014717=Translation elongation factor EF1B/ribosomal protein S6" CG15016 16-Dec-15 2015_12 "ENSDARG00000039543(zgc:153390),ENSDARG00000070130" WBGene00020037(R12E2.12) ENSMUSG00000039680(Mrps6) ENSG00000214955 "viable,visible" trichogen cell FBgn0000446 dhm dark hairy margins http://flybase.net/reports/FBgn0000446.html gene 16-Dec-15 2015_12 "visible,viable,fertile,good" "scutellar bristle,wing,wing vein,abdomen & macrochaeta" FBgn0031849 CG11327 http://flybase.net/reports/FBgn0031849.html protein_coding_gene CG11327 16-Dec-15 2015_12 FBgn0266388 CR45028 http://flybase.net/reports/FBgn0266388.html non_protein_coding_gene CR45028 16-Dec-15 2015_12 FBgn0023004 l(3)s9999 lethal (3) s9999 http://flybase.net/reports/FBgn0023004.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002274 l(3)70Ab lethal (3) 70Ab http://flybase.net/reports/FBgn0002274.html gene l(3)ZF2 16-Dec-15 2015_12 lethal FBgn0065667 l(2)SH0694 lethal (2) SH0694 http://flybase.net/reports/FBgn0065667.html gene l(2)SH2 0694 16-Dec-15 2015_12 "lethal,recessive" FBgn0265786 CR44575 http://flybase.net/reports/FBgn0265786.html non_protein_coding_gene lincRNA.51 CR44575 16-Dec-15 2015_12 FBgn0036306 CG10973 http://flybase.net/reports/FBgn0036306.html protein_coding_gene "IPR011989=Armadillo-like helical, IPR013918=Nucleotide exchange factor Fes1, IPR016024=Armadillo-type fold" CG10973 16-Dec-15 2015_12 ENSDARG00000007665(zgc:55259) YBR101C(FES1) ENSXETG00000022926(hspbp1) ENSMUSG00000063802(Hspbp1) ENSG00000133265(HSPBP1) viable DRSC09813 I 1.942195018 -0.187883553 -0.705177909 0.745874932 -0.837870468 -0.1016987 FBgn0023026 l(2)FZ13 lethal (2) FZ13 http://flybase.net/reports/FBgn0023026.html gene 16-Dec-15 2015_12 FBgn0037421 CG15594 http://flybase.net/reports/FBgn0037421.html protein_coding_gene CG15594 16-Dec-15 2015_12 viable FBgn0025630 CG4061 http://flybase.net/reports/FBgn0025630.html protein_coding_gene 0003963=RNA-3'-phosphate cyclase activity 0006396=RNA processing 0005634=nucleus "EG:22E5.3, RTC1_DROME" "IPR013791=RNA 3'-terminal phosphate cyclase, insert domain, IPR000228=RNA 3'-terminal phosphate cyclase, IPR013792=RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta, IPR023797=RNA 3'-terminal phosphate cyclase domain, IPR017770=RNA 3'-terminal phosphate cyclase type 1" CG4061 16-Dec-15 2015_12 ENSDARG00000002215(rtcd1) ENSMUSG00000000339(Rtcd1) ENSG00000137996(RTCD1) viable FBgn0060958 l(3)S033702a lethal (3) S033702a http://flybase.net/reports/FBgn0060958.html gene 0337/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0033518 Prx2540-2 Peroxiredoxin 2540-2 http://flybase.net/reports/FBgn0033518.html protein_coding_gene "0004601=peroxidase activity, 0016209=antioxidant activity, 0008379=thioredoxin peroxidase activity, 0004602=glutathione peroxidase activity" "0055114=oxidation-reduction process, 0042744=hydrogen peroxide catabolic process" 0005829=cytosol "DPx-2540-2, Prx2540, CG11765, peroxiredoxin 2540, Peroxiredoxin 2540, DPx2540, Peroxiredoxin" "IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336=Thioredoxin-like fold, IPR024706=Peroxiredoxin, AhpC-type, IPR019479=Peroxiredoxin, C-terminal" CG11765 16-Dec-15 2015_12 YBL064C(PRX1) WBGene00021401(prdx-6) FBgn0033640 CG13198 http://flybase.net/reports/FBgn0033640.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG13198 16-Dec-15 2015_12 viable FBgn0069949 CG41074 http://flybase.net/reports/FBgn0069949.html FBan0041074 protein_coding_gene 16-Dec-15 2015_12 FBgn0266258 CR44953 http://flybase.net/reports/FBgn0266258.html non_protein_coding_gene lincRNA.895 CR44953 16-Dec-15 2015_12 FBgn0029038 l(2)I16 lethal (2) I16 http://flybase.net/reports/FBgn0029038.html gene I16 16-Dec-15 2015_12 "lethal,recessive" FBgn0069174 mcl(2)Z5838 mcl(2)Z5838 http://flybase.net/reports/FBgn0069174.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0082184 l(3)e02803 lethal (3) e02803 http://flybase.net/reports/FBgn0082184.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038659 EndoA Endophilin A http://flybase.net/reports/FBgn0038659.html protein_coding_gene "0005543=phospholipid binding, 0042171=lysophosphatidic acid acyltransferase activity" "0050803=regulation of synapse structure or activity, 0048488=synaptic vesicle endocytosis, 0007269=neurotransmitter secretion, 0097320=membrane tubulation" "0005737=cytoplasm, 0005829=cytosol, 0016020=membrane" "EndoA, Endo, endo, endophilin A, D-endo, endophilin, Endophilin A, Endophilin-A, CG14296, Dendo-A, EndophilinA, endophilinA, Endophilin, D-endoA, endoA" "IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR001452=SH3 domain, IPR013315=Spectrin alpha chain, SH3 domain, IPR028501=Endophilin-A, IPR004148=BAR domain" CG14296 16-Dec-15 2015_12 "ENSDARG00000002642(sh3gl1b),ENSDARG00000067958(sh3gl1a),ENSDARG00000013360,ENSDARG00000023600(LOC100334972),ENSDARG00000039901,ENSDARG00000007302(sh3gl3)" WBGene00006791(unc-57) "ENSXETG00000007747(),ENSXETG00000015811(sh3gl1),ENSXETG00000018020(SH3GL2)" "ENSMUSG00000030638(Sh3gl3),ENSMUSG00000003200(Sh3gl1),ENSMUSG00000028488(Sh3gl2)" "ENSG00000141985(SH3GL1),ENSG00000107295(SH3GL2),ENSG00000140600(SH3GL3)" "viable,neuroanatomy defective,partially lethal - majority die,lethal,recessive,neurophysiology defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,paralytic,lethal - all die before end of larval stage,some die during larval stage,developmental rate defective,germline clone,somatic clone,phototaxis defective" "NMJ bouton,supernumerary,synapse[-],presynaptic active zone[-],presynaptic active zone,presynaptic active zonern--14,eye,wing,ommatidium,interommatidial bristle,bouton,motor neuron,eye photoreceptor cell,somatic clone,eye photoreceptor cell & synaptic vesicle | somatic clone[-],synaptic vesicle[-],retina,embryonic/larval neuromuscular junction" FBgn0264671 wobbly-lumens wobbly lumens http://flybase.net/reports/FBgn0264671.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0024534 l(3)L1170b lethal (3) L1170b http://flybase.net/reports/FBgn0024534.html gene l(3)L1170 16-Dec-15 2015_12 "lethal,recessive" FBgn0031675 CG9121 http://flybase.net/reports/FBgn0031675.html protein_coding_gene 0005200=structural constituent of cytoskeleton "0035556=intracellular signal transduction, 0007016=cytoskeletal anchoring at plasma membrane" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR001496=SOCS box domain" CG9121 16-Dec-15 2015_12 WBGene00019782(M60.7) "ENSMUSG00000034768(Asb16),ENSMUSG00000067081(Asb18),ENSMUSG00000038204(Asb10),ENSMUSG00000042607(Asb4)" "ENSG00000161664(ASB16),ENSG00000146926(ASB10),ENSG00000182177(ASB18),ENSG00000005981(ASB4)" viable DRSC03142 I 1.74035333 -0.317514843 -0.666486795 -0.321002584 -0.296404468 -0.615194887 FBgn0052117 CG32117 http://flybase.net/reports/FBgn0052117.html protein_coding_gene CG32117 16-Dec-15 2015_12 viable FBgn0259533 GG01083 http://flybase.net/reports/FBgn0259533.html gene 16-Dec-15 2015_12 visible "leg,arista" FBgn0260068 2L2572 http://flybase.net/reports/FBgn0260068.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,viable,lethal" "embryonic/larval tracheal system,somatic clone" FBgn0022234 l(2)k02802 lethal (2) k02802 http://flybase.net/reports/FBgn0022234.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024284 Su(hh)2A Suppressor of hedgehog 2A http://flybase.net/reports/FBgn0024284.html gene "0035214=eye-antennal disc development, 0001700=embryonic development via the syncytial blastoderm" S(hh)2A 16-Dec-15 2015_12 FBgn0005362 Sy Stubby http://flybase.net/reports/FBgn0005362.html gene 16-Dec-15 2015_12 male sterile "macrochaeta,humeral bristle,notopleural bristle" FBgn0034910 CG4763 http://flybase.net/reports/FBgn0034910.html protein_coding_gene CG4763 16-Dec-15 2015_12 viable FBgn0065110 ppk10 pickpocket 10 http://flybase.net/reports/FBgn0065110.html "FBgn0054042, FBgn0082899" protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "BP1007, unnamed, PPK10, CG34042" "IPR001873=Na+ channel, amiloride-sensitive" CG34042 16-Dec-15 2015_12 viable FBgn0259865 Su(Ste):CR42434 Su(Ste):CR42434 http://flybase.net/reports/FBgn0259865.html non_protein_coding_gene CR42434 CR42434 16-Dec-15 2015_12 FBgn0022372 Pt-26 Adult protein-26 http://flybase.net/reports/FBgn0022372.html gene 16-Dec-15 2015_12 FBgn0031650 CG14044 http://flybase.net/reports/FBgn0031650.html protein_coding_gene CG14044 16-Dec-15 2015_12 FBgn0051638 CG31638 http://flybase.net/reports/FBgn0051638.html "FBgn0031823, FBgn0031825" protein_coding_gene 0003774=motor activity 0016459=myosin complex "CG13764, CG9545" IPR002928=Myosin tail CG31638 16-Dec-15 2015_12 ENSDARG00000003872(zgc:77294) ENSMUSG00000063605(Ccdc102a) ENSG00000135736(CCDC102A) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02269 IE 1.026565862 -2.205610785 0.754556429 -1.695466246 -1.384689286 -1.250418604 FBgn0260607 2L1809 http://flybase.net/reports/FBgn0260607.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0029747 CG5062 http://flybase.net/reports/FBgn0029747.html FBgn0063733 protein_coding_gene 0005654=nucleoplasm "BcDNA:AT13663, FBgn0029747" CG5062 16-Dec-15 2015_12 viable FBgn0025758 l(3)93DFd lethal (3) 93DFd http://flybase.net/reports/FBgn0025758.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0041006 CG13302 http://flybase.net/reports/FBgn0041006.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065751 l(2)SH0497 lethal (2) SH0497 http://flybase.net/reports/FBgn0065751.html gene l(2)SH2 0497 16-Dec-15 2015_12 "lethal,recessive" FBgn0036213 RpL10Ab Ribosomal protein L10Ab http://flybase.net/reports/FBgn0036213.html "FBgn0026276, FBgn0064847" protein_coding_gene "0003723=RNA binding, 0003735=structural constituent of ribosome" "0007052=mitotic spindle organization, 0006412=translation, 0051298=centrosome duplication, 0000022=mitotic spindle elongation" 0022625=cytosolic large ribosomal subunit "L10Ab, RpL10Ae, RpL10A, CG7283, anon-EST:Posey188, BcDNA:RH06366" "IPR002143=Ribosomal protein L1, IPR016094=Ribosomal protein L1, 2-layer alpha/beta-sandwich, IPR028364=Ribosomal protein L1/ribosomal biogenesis protein, IPR023674=Ribosomal protein L1-like, IPR016095=Ribosomal protein L1, 3-layer alpha/beta-sandwich" CG7283 16-Dec-15 2015_12 ENSDARG00000042905(rpl10a) "YPL220W(RPL1A),YGL135W(RPL1B)" WBGene00004412(rpl-1) ENSXETG00000012374(RPL10A) "ENSMUSG00000037805(Rpl10a),ENSMUSG00000061988(Rpl10a-ps2)" "ENSG00000198755(RPL10A),ENSG00000188873,ENSG00000215264" "lethal,lethal - all die before end of larval stage" "follicle cell,germline clone,nucleus | germline clone,egg chamber,nucleolus | germline clone" DRSC10798 IEK -0.652374103 -2.206845515 1.887680279 -3.720063927 0.948899893 4.16742067 FBgn0013711 muc midline uncoordinated http://flybase.net/reports/FBgn0013711.html gene "0007625=grooming behavior, 0008053=mitochondrial fusion" 0005967=mitochondrial pyruvate dehydrogenase complex 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0267314 CR45750 http://flybase.net/reports/FBgn0267314.html non_protein_coding_gene CR45750 16-Dec-15 2015_12 FBgn0086253 rumi rumi http://flybase.net/reports/FBgn0086253.html "FBgn0084416, FBgn0051152, FBgn0039021" protein_coding_gene 0046527=glucosyltransferase activity "0033577=protein glycosylation in endoplasmic reticulum, 0007030=Golgi organization, 0042052=rhabdomere development, 0008593=regulation of Notch signaling pathway, 0045746=negative regulation of Notch signaling pathway, 0045747=positive regulation of Notch signaling pathway, 0007219=Notch signaling pathway, 2000035=regulation of stem cell division" "0012505=endomembrane system, 0005788=endoplasmic reticulum lumen" "Rumi, CG31152, CG17138" IPR006598=Lipopolysaccharide-modifying protein CG31152 16-Dec-15 2015_12 ENSDARG00000053463(zgc:123318) ENSXETG00000014465(KDELC2) ENSMUSG00000034064(Ktelc1) ENSG00000163389(POGLUT1) "viable,visible,body color defective,recessive,somatic clone,heat sensitive,temperature conditional,neuroanatomy defective,short lived,eclosion defective,partially lethal - majority die,lethal" "trichogen cell,mesothoracic tergum,chaeta,somatic clone,temperature conditional,microchaeta,heat sensitive,wing vein,enterocyte of posterior adult midgut epithelium,intestinal stem cell,supernumerary,wing margin,embryonic/larval neuron,notal microchaeta,leg,joint,mechanosensory chaeta" FBgn0027299 l(1)G0128 lethal (1) G0128 http://flybase.net/reports/FBgn0027299.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal,female" FBgn0035655 CG13291 http://flybase.net/reports/FBgn0035655.html protein_coding_gene 16-Dec-15 2015_12 FBgn0243497 Gr21a::Orco http://flybase.net/reports/FBgn0243497.html engineered_fusion_gene Gr21a::Or83b 16-Dec-15 2015_12 FBgn0040154 l(1)G0467 lethal (1) G0467 http://flybase.net/reports/FBgn0040154.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0035256 CG13930 http://flybase.net/reports/FBgn0035256.html protein_coding_gene "0042623=ATPase activity, coupled, 0003774=motor activity" 0007018=microtubule-based movement "0030286=dynein complex, 0005875=microtubule associated complex, 0005868=cytoplasmic dynein complex" unnamed "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG13930 16-Dec-15 2015_12 ENSDARG00000044400(wdr78) ENSMUSG00000035126(Wdr78) viable FBgn0037870 CG18577 http://flybase.net/reports/FBgn0037870.html protein_coding_gene CG18577 16-Dec-15 2015_12 viable FBgn0014260 l(2)N7-6 lethal (2) N7-6 http://flybase.net/reports/FBgn0014260.html gene N7-6 16-Dec-15 2015_12 "lethal,recessive" FBgn0029726 CG15471 http://flybase.net/reports/FBgn0029726.html protein_coding_gene IPR018392=LysM domain CG15471 16-Dec-15 2015_12 viable DRSC18054 I -0.425731854 -1.852281866 -0.833618778 -0.662699746 -0.21790856 0.459405163 FBgn0264305 CG43783 http://flybase.net/reports/FBgn0264305.html "FBgn0262573, FBgn0035937" protein_coding_gene 0012505=endomembrane system "CG43113, CG5741" CG43783 16-Dec-15 2015_12 WBGene00018872(F55C12.5) ENSXETG00000007222(TEX2) ENSMUSG00000040548(Tex2) ENSG00000136478(TEX2) FBgn0067877 Mod(Prat:bw)3-1 Mod(Prat:bw)3-1 http://flybase.net/reports/FBgn0067877.html gene Mod-3-1 16-Dec-15 2015_12 "lethal,recessive" FBgn0035901 CG6745 http://flybase.net/reports/FBgn0035901.html protein_coding_gene "0003723=RNA binding, 0009982=pseudouridine synthase activity" 0001522=pseudouridine synthesis CT20937 "IPR011760=Pseudouridine synthase, TruD, insertion domain, IPR001656=Pseudouridine synthase, TruD, IPR020103=Pseudouridine synthase, catalytic domain" CG6745 16-Dec-15 2015_12 "ENSDARG00000069780(pus7l),ENSDARG00000062808,ENSDARG00000057542" YOR243C(PUS7) WBGene00007101(B0024.11) ENSXETG00000023207(TEgg007f18.1) ENSMUSG00000057541(Pus7) ENSG00000091127(PUS7) "partially lethal - majority die,some die during pupal stage" FBgn0023531 CG32809 http://flybase.net/reports/FBgn0023531.html "FBgn0025379, FBgn0025386, FBgn0052809" protein_coding_gene "CG3783, EG:9D2.2, CG3791, CG3737, EG:73D1.1, EG:171E4.3" "IPR022782=Actin interacting protein 3, C-terminal" CG32809 16-Dec-15 2015_12 "ENSDARG00000059773(LOC565863),ENSDARG00000059333,ENSDARG00000031658" WBGene00022180(Y71H2AM.15) ENSXETG00000005906(KIAA1217) "ENSMUSG00000038453(Srcin1),ENSMUSG00000036617(Etl4)" "ENSG00000120549(KIAA1217),ENSG00000017373(SRCIN1)" viable FBgn0061130 l(3)S002501b lethal (3) S002501b http://flybase.net/reports/FBgn0061130.html gene 0025/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000768 fs(1)A1042 female sterile (1) A1042 http://flybase.net/reports/FBgn0000768.html gene fs(1)1042ts 16-Dec-15 2015_12 "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of pupal stage,non-rescuable maternal effect,some die during pupal stage" blastoderm embryo FBgn0067065 Nrt::Wnt5 Nrt::Wnt5 http://flybase.net/reports/FBgn0067065.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0039250 Mink Mitotic spindle and nuclear protein http://flybase.net/reports/FBgn0039250.html protein_coding_gene 0008017=microtubule binding "0000281=mitotic cytokinesis, 0040001=establishment of mitotic spindle localization" "0072686=mitotic spindle, 0005874=microtubule, 0005634=nucleus" "mitotic spindle and nuclear protein, CG11120" IPR026756=Nucleolar and spindle-associated protein 1 CG11120 16-Dec-15 2015_12 "viable,fertile" FBgn0031522 CG3285 http://flybase.net/reports/FBgn0031522.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG3285 16-Dec-15 2015_12 "YOL103W(ITR2),YDR497C(ITR1)" "viable,fertile" FBgn0025338 anon-58Fe anon-58Fe http://flybase.net/reports/FBgn0025338.html gene 8-Apr 16-Dec-15 2015_12 FBgn0002877 mur murrey http://flybase.net/reports/FBgn0002877.html gene 16-Dec-15 2015_12 "male sterile,recessive,female sterile,eye color defective" "pigment cell,macrochaeta" FBgn0000684 flrdG flight reduced G http://flybase.net/reports/FBgn0000684.html gene 0007629=flight behavior 16-Dec-15 2015_12 "jumping defective,locomotor behavior defective,flight defective" FBgn0024571 l(3)L7251 lethal (3) L7251 http://flybase.net/reports/FBgn0024571.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015820 Su(spl) Suppressor of split http://flybase.net/reports/FBgn0015820.html gene 16-Dec-15 2015_12 FBgn0033235 CG8728 http://flybase.net/reports/FBgn0033235.html protein_coding_gene "0004222=metalloendopeptidase activity, 0046872=metal ion binding" 0016485=protein processing 0005759=mitochondrial matrix "IPR007863=Peptidase M16, C-terminal, IPR001431=Peptidase M16, zinc-binding site, IPR011249=Metalloenzyme, LuxS/M16 peptidase-like, IPR011765=Peptidase M16, N-terminal, IPR011237=Peptidase M16 domain" CG8728 16-Dec-15 2015_12 YHR024C(MAS2) WBGene00022159(mppa-1) ENSXETG00000000748(PMPCA) ENSMUSG00000026926(Pmpca) ENSG00000165688(PMPCA) "viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065759 l(2)SH0480 lethal (2) SH0480 http://flybase.net/reports/FBgn0065759.html gene l(2)SH2 0480 16-Dec-15 2015_12 "lethal,recessive" FBgn0044391 Scim37 Sensitized chromosome inheritance modifier 37 http://flybase.net/reports/FBgn0044391.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0266560 EP2269 http://flybase.net/reports/FBgn0266560.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0029961 Ir7a Ionotropic receptor 7a http://flybase.net/reports/FBgn0029961.html protein_coding_gene 0015276=ligand-gated ion channel activity "0009593=detection of chemical stimulus, 0050909=sensory perception of taste" 0016021=integral component of membrane "IR7a, ionotropic receptor 7a, DmelIR7a, CG12663" CG12663 16-Dec-15 2015_12 viable FBgn0028059 l(3)S093909 lethal (3) S093909 http://flybase.net/reports/FBgn0028059.html gene 0939/09 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0046885 Gr98d Gustatory receptor 98d http://flybase.net/reports/FBgn0046885.html "FBgn0039524, FBgn0041223, FBgn0045467, FBgn0051061" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 98B.1, Gr98A1, GR98B.1, CG31061, 98B.1, CG12884, GR98d, Gr98B1" IPR013604=7TM chemoreceptor CG31061 16-Dec-15 2015_12 viable FBgn0065542 l(2)SH1058 lethal (2) SH1058 http://flybase.net/reports/FBgn0065542.html gene l(2)SH2 1058 16-Dec-15 2015_12 "lethal,recessive" FBgn0086407 BG01574 http://flybase.net/reports/FBgn0086407.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0014188 har56 har56 http://flybase.net/reports/FBgn0014188.html gene "Har56, har" 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0266739 CR45212 http://flybase.net/reports/FBgn0266739.html non_protein_coding_gene CR45212 16-Dec-15 2015_12 FBgn0029818 GAA1 Glycosylphosphatidylinositol anchor attachment 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0029818.html protein_coding_gene "0042996=regulation of Golgi to plasma membrane protein transport, 0016255=attachment of GPI anchor to protein, 0045313=rhabdomere membrane biogenesis" "0012505=endomembrane system, 0042765=GPI-anchor transamidase complex, 0005783=endoplasmic reticulum" CG3033 IPR007246=GPI transamidase component Gaa1 CG3033 16-Dec-15 2015_12 YLR088W(GAA1) WBGene00018006(F33D11.9) ENSXETG00000004682(Q5EB45_XENTR) ENSMUSG00000022561(Gpaa1) ENSG00000197858(GPAA1) "lethal - all die before end of larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,somatic clone" FBgn0023550 CG18031 http://flybase.net/reports/FBgn0023550.html FBgn0029604 protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity EG:103B4.2 "IPR016040=NAD(P)-binding domain, IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding" CG18031 16-Dec-15 2015_12 viable FBgn0027339 jim jim http://flybase.net/reports/FBgn0027339.html "FBgn0016051, FBgn0024201, FBgn0037192, FBgn0064775" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0031935=regulation of chromatin silencing, 0048813=dendrite morphogenesis" 0005634=nucleus "CG11352, ovfc.K, Jim, OVK, BcDNA:SD14927, ovk" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG11352 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage >=S9 , adult stage && oogenesis stage | stage >=S10A , adult stage && oogenesis stage | stage >=S12 " " nurse follicle cell

, oocyte associated follicle cell

" " embryonic stage | stage 15 , adult stage && oogenesis stage | stage >=S10 , adult stage && oogenesis stage | stage >=S9 " " pharyngeal muscle

, oocyte associated follicle cell

, anterior embryonic/larval midgut

, nurse follicle cell

, embryonic/larval hindgut

" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,dorsal multidendritic neuron ddaC" FBgn0259867 Su(Ste):CR42436 Su(Ste):CR42436 http://flybase.net/reports/FBgn0259867.html non_protein_coding_gene CR42436 CR42436 16-Dec-15 2015_12 FBgn0030615 Cyp4s3 Cyp4s3 http://flybase.net/reports/FBgn0030615.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "cytochrome P450, CG9081, 4s3" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG9081 16-Dec-15 2015_12 YMR015C(ERG5) "viable,fertile" FBgn0265538 CR44388 http://flybase.net/reports/FBgn0265538.html non_protein_coding_gene lincRNA.332 CR44388 16-Dec-15 2015_12 FBgn0038012 CG10013 http://flybase.net/reports/FBgn0038012.html protein_coding_gene IPR019193=Ubiquitin-conjugating enzyme E2-binding protein CG10013 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0037780 CG3925 http://flybase.net/reports/FBgn0037780.html protein_coding_gene CG3925 16-Dec-15 2015_12 ENSDARG00000054250(crbn) ENSXETG00000005146(CRBN_XENTR) ENSMUSG00000005362(Crbn) ENSG00000113851(CRBN) viable DRSC30024 K -0.663151116 -0.434799196 -0.205782935 0.401584389 -0.09241333 1.665540493 FBgn0266356 CR45004 http://flybase.net/reports/FBgn0266356.html non_protein_coding_gene CR45004 16-Dec-15 2015_12 FBgn0037549 CG7878 http://flybase.net/reports/FBgn0037549.html protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0003723=RNA binding, 0004386=helicase activity" "cg7878, DmRH26" "IPR004087=K Homology domain, IPR011545=DEAD/DEAH box helicase domain, IPR004088=K Homology domain, type 1, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650=Helicase, C-terminal" CG7878 16-Dec-15 2015_12 ENSDARG00000022614(ddx43) WBGene00013214(Y54G11A.3) ENSXETG00000011767() ENSMUSG00000070291(Ddx43) "ENSG00000080007(DDX43),ENSG00000184735(DDX53)" "partially lethal - majority die,some die during pupal stage,viable,fertile" DRSC16330 E -0.692833852 -0.732993935 -1.917114001 0.448123068 0.412283112 1.415581724 FBgn0004217 l(3)84Fe lethal (3) 84Fe http://flybase.net/reports/FBgn0004217.html gene 16-Dec-15 2015_12 lethal FBgn0259554 B2010 http://flybase.net/reports/FBgn0259554.html gene 16-Dec-15 2015_12 visible "unguis,leg" FBgn0060676 l(3)S077301 lethal (3) S077301 http://flybase.net/reports/FBgn0060676.html gene 0773/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0025139 pll::Src64B pll::Src64B http://flybase.net/reports/FBgn0025139.html engineered_fusion_gene src-pll 16-Dec-15 2015_12 FBgn0001998 l(2)36Ab lethal (2) 36Ab http://flybase.net/reports/FBgn0001998.html gene "l(2L)HT-6, l(2)HT-6" 16-Dec-15 2015_12 "lethal,recessive" FBgn0015455 l(2)24CDb lethal (2) 24CDb http://flybase.net/reports/FBgn0015455.html gene l(2)g 16-Dec-15 2015_12 lethal FBgn0058103 CG40103 http://flybase.net/reports/FBgn0058103.html FBan0040103 protein_coding_gene 16-Dec-15 2015_12 FBgn0085233 CG34204 http://flybase.net/reports/FBgn0085233.html protein_coding_gene CG34204 16-Dec-15 2015_12 FBgn0050321 CG30321 http://flybase.net/reports/FBgn0050321.html protein_coding_gene 0046331=lateral inhibition 16-Dec-15 2015_12 "viable,visible" chaeta FBgn0013237 E(var)195 E(var)195 http://flybase.net/reports/FBgn0013237.html gene E-var(3)10 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0010287 Trf TBP-related factor http://flybase.net/reports/FBgn0010287.html protein_coding_gene "0008134=transcription factor binding, 0001046=core promoter sequence-specific DNA binding, 0003677=DNA binding, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0001092=TFIIA-class transcription factor binding, 0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0001093=TFIIB-class transcription factor binding" "0006359=regulation of transcription from RNA polymerase III promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006383=transcription from RNA polymerase III promoter, 0006384=transcription initiation from RNA polymerase III promoter, 0009790=embryo development" "0005634=nucleus, 0005669=transcription factor TFIID complex, 0005700=polytene chromosome, 0005667=transcription factor complex" "dTRF-1, CG7562, X70838, Trf1, TRF1, TRF, trf, dTRF1" "IPR012295=Beta2-adaptin/TBP, C-terminal domain, IPR000814=TATA-box binding protein, IPR030491=TATA-box binding protein, conserved site" CG7562 16-Dec-15 2015_12 " embryonic stage , spermatogenesis && adult stage " " supraesophageal ganglion

, testis

, embryonic central nervous system | restricted

, spermatocyte

" "male sterile,hyperactive,recessive,behavior defective,viable" "spermatozoon,spermatocyte" FBgn0070023 BG00489 BG00489 http://flybase.net/reports/FBgn0070023.html gene 16-Dec-15 2015_12 stress response defective FBgn0014332 l(3)ry98 lethal (3) ry98 http://flybase.net/reports/FBgn0014332.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040012 CG17495 http://flybase.net/reports/FBgn0040012.html protein_coding_gene 16-Dec-15 2015_12 FBgn0052600 dpr8 defective proboscis extension response 8 http://flybase.net/reports/FBgn0052600.html "FBgn0030564, FBgn0030567, FBgn0030568" protein_coding_gene 0007606=sensory perception of chemical stimulus "CG11477, dpr8, CG14415, CT16867, Dpr-8, CG5291, CG32600, Dpr8" "IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013106=Immunoglobulin V-set domain, IPR013151=Immunoglobulin" CG32600 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) viable FBgn0033624 CG12384 http://flybase.net/reports/FBgn0033624.html "FBgn0064838, FBgn0064965" protein_coding_gene "BcDNA:RH17411, BcDNA:GH16986" IPR024130=DAP1/DAPL1 CG12384 16-Dec-15 2015_12 ENSDARG00000000069(dap1a) ENSXETG00000025633(dap) ENSMUSG00000039168(Dap) viable FBgn0023526 CG2865 http://flybase.net/reports/FBgn0023526.html FBgn0066840 protein_coding_gene 0051726=regulation of cell cycle "EG:25E8.4, anon-WO03040301.165" IPR009263=SERTA domain CG2865 16-Dec-15 2015_12 pupal stage salivary gland

viable FBgn0262998 CR43306 http://flybase.net/reports/FBgn0262998.html non_protein_coding_gene lincRNA.602 CR43306 16-Dec-15 2015_12 FBgn0035977 PGRP-LF Peptidoglycan recognition protein LF http://flybase.net/reports/FBgn0035977.html "FBgn0061861, FBgn0063601" protein_coding_gene "0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0008270=zinc ion binding" "0098542=defense response to other organism, 0009253=peptidoglycan catabolic process, 0006952=defense response, 0008340=determination of adult lifespan, 0009617=response to bacterium, 0046329=negative regulation of JNK cascade, 0019731=antibacterial humoral response, 0061057=peptidoglycan recognition protein signaling pathway" "0005887=integral component of plasma membrane, 0031240=external side of cell outer membrane" "peptidoglycan recognition protein, PGRPLF, Peptidoglycan-recognition protein-LF, pgrp-lf, CG4437, PRGP-like, anon-WO0118547.581, PGRP-like" "IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria" CG4437 16-Dec-15 2015_12 "ENSMUSG00000042244(Pglyrp3),ENSMUSG00000042250(Pglyrp4)" "ENSG00000159527(PGLYRP3),ENSG00000163218(PGLYRP4)" "visible,immune response defective,partially lethal - majority die,long lived" wing FBgn0083047 snoRNA:ë¬18S-1377e snoRNA:ë¬18S-1377e http://flybase.net/reports/FBgn0083047.html snoRNA_gene "CR34625, psi18S-1377e, Psi18S-1377e" CR34625 16-Dec-15 2015_12 FBgn0267575 CR45915 http://flybase.net/reports/FBgn0267575.html non_protein_coding_gene CR45915 16-Dec-15 2015_12 FBgn0052803 CG32803 http://flybase.net/reports/FBgn0052803.html FBgn0029595 protein_coding_gene CG14819 CG32803 16-Dec-15 2015_12 "viable,fertile" FBgn0011651 Mads-3 Mads-3 http://flybase.net/reports/FBgn0011651.html gene 16-Dec-15 2015_12 FBgn0010718 l(3)00506 lethal (3) 00506 http://flybase.net/reports/FBgn0010718.html gene l(3)506 16-Dec-15 2015_12 "lethal,recessive" FBgn0005108 GustS Gustatory S http://flybase.net/reports/FBgn0005108.html gene 16-Dec-15 2015_12 taste perception defective taste bristle FBgn0013487 l(1)5PP10 lethal (1) 5PP10 http://flybase.net/reports/FBgn0013487.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" embryonic segment & embryonic/first instar larval cuticle | germ-line clone FBgn0003731 Egfr Epidermal growth factor receptor http://flybase.net/reports/FBgn0003731.html "FBgn0010599, FBgn0022793" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0004888=transmembrane signaling receptor activity, 0008313=gurken-activated receptor activity, 0005006=epidermal growth factor-activated receptor activity, 0004713=protein tyrosine kinase activity, 0019904=protein domain specific binding" "0007476=imaginal disc-derived wing morphogenesis, 0035088=establishment or maintenance of apical/basal cell polarity, 0007298=border follicle cell migration, 0007173=epidermal growth factor receptor signaling pathway, 0000086=G2/M transition of mitotic cell cycle, 0016318=ommatidial rotation, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0007420=brain development, 0048546=digestive tract morphogenesis, 0007443=Malpighian tubule morphogenesis, 0007444=imaginal disc development, 0045468=regulation of R8 cell spacing in compound eye, 0048139=female germ-line cyst encapsulation, 0007474=imaginal disc-derived wing vein specification, 0035225=determination of genital disc primordium, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0008586=imaginal disc-derived wing vein morphogenesis, 0045466=R7 cell differentiation, 2001234=negative regulation of apoptotic signaling pathway, 0009950=dorsal/ventral axis specification, 0030031=cell projection assembly, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0008314=gurken signaling pathway, 0008071=maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded, 0016330=second mitotic wave involved in compound eye morphogenesis, 0007422=peripheral nervous system development, 0003015=heart process, 0009952=anterior/posterior pattern specification, 0001654=eye development, 0016203=muscle attachment, 0001751=compound eye photoreceptor cell differentiation, 0007369=gastrulation, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0048149=behavioral response to ethanol, 0016337=single organismal cell-cell adhesion, 0016333=morphogenesis of follicular epithelium, 0007310=oocyte dorsal/ventral axis specification, 0046843=dorsal appendage formation, 0007469=antennal development, 0009880=embryonic pattern specification, 0007472=wing disc morphogenesis, 0007350=blastoderm segmentation, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0045165=cell fate commitment, 0035309=wing and notum subfield formation, 0048140=male germ-line cyst encapsulation, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0030718=germ-line stem cell maintenance, 0030381=chorion-containing eggshell pattern formation, 0008355=olfactory learning, 0000578=embryonic axis specification, 0001742=oenocyte differentiation, 0022008=neurogenesis, 0007479=leg disc proximal/distal pattern formation, 0007482=haltere development, 0001745=compound eye morphogenesis, 0008284=positive regulation of cell proliferation, 0007391=dorsal closure, 0045610=regulation of hemocyte differentiation, 0090303=positive regulation of wound healing, 0048749=compound eye development, 0007431=salivary gland development, 0035202=tracheal pit formation in open tracheal system, 0007346=regulation of mitotic cell cycle, 0007424=open tracheal system development, 0035310=notum cell fate specification, 0048865=stem cell fate commitment, 0043066=negative regulation of apoptotic process, 0009953=dorsal/ventral pattern formation, 0042676=compound eye cone cell fate commitment, 0042694=muscle cell fate specification, 0048477=oogenesis, 0007390=germ-band shortening, 0002009=morphogenesis of an epithelium, 0007367=segment polarity determination, 0035160=maintenance of epithelial integrity, open tracheal system, 0001752=compound eye photoreceptor fate commitment, 0007447=imaginal disc pattern formation, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 0007455=eye-antennal disc morphogenesis, 0008406=gonad development, 0007473=wing disc proximal/distal pattern formation, 0007477=notum development, 0007314=oocyte anterior/posterior axis specification, 0035277=spiracle morphogenesis, open tracheal system, 0007309=oocyte axis specification, 0001709=cell fate determination, 0007421=stomatogastric nervous system development" "0005886=plasma membrane, 0005887=integral component of plasma membrane, 0035230=cytoneme" "DER flb, EC2-4, top/flb, Ellipse torpedo, DEGFR, faint little ball, EGFR, TOP, l(2)57DEFa, l(2)57EFa, Drosophila epidermal growth factor receptor homologue, Egf-r, top, Torpedo/DER, EGF receptor, EGF-receptor, dEgfr, Elp, DER/EGFR, D-EGFR, Elp-B1, dEGFR1, l(2)57Ea, Flb, torpedo, EGF Receptor, Der, d-egf-r, unnamed, Degfr, EGF-R, l(2)05351, DER, Egf, epidermal growth factor receptor, Egf receptor, HD-33, EFG-R, Elp-1, torpedo/Egfr, c-erbB, der, Torpedo, dEGFr, torpedo/egfr, DmHD-33, EGfr, torpedo/DER, Ellipse, flb, mor1, morphological defects 1, EgfR, Torpedo/Egfr, Elp-B1RB1, CG10079, D-Egf, DER-Ellipse, degfr, egfr, Tor, dEGFR, EK2-6, DER/top, DER/torpedo, Epidermal Growth Factor Receptor, DEgfr, Epidermal growth factor Receptor, top/DER, El, C-erb, l(2)09261, EGFr, DER1" "IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR023410=14-3-3 domain, IPR023409=14-3-3 protein, conserved site, IPR006212=Furin-like repeat, IPR000308=14-3-3 protein, IPR017441=Protein kinase, ATP binding site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR000494=Receptor L-domain, IPR006211=Furin-like cysteine-rich domain" CG10079 16-Dec-15 2015_12 "ENSDARG00000006202(erbb3a),ENSDARG00000036993(erbb3b),ENSDARG00000061142,ENSDARG00000063207(LOC570291),ENSDARG00000013847(egfra)" WBGene00002299(let-23) "ENSXETG00000015826(EGFR),ENSXETG00000000413(ERBB4),ENSXETG00000015145(ERBB2),ENSXETG00000009463(ERBB3)" "ENSG00000065361(ERBB3),ENSG00000178568(ERBB4),ENSG00000146648(EGFR),ENSG00000141736(ERBB2)" " embryonic stage | stage 17 && larval stage , adult stage , embryonic stage | stage 5, larval stage | third instar , larval stage , adult stage | male , oogenesis stage , larval stage | third instar && P-stage , embryonic stage | stage >7 , embryonic stage | stage >14 , embryonic stage , embryonic stage | 10-14hr , embryonic stage | stage 11-14 , embryonic stage | 24hr , pupal stage , embryonic stage | early-mid , embryonic stage | stage 6-7 , embryonic stage | stage 15,16 , embryonic stage | stage 4-5 , adult stage | female , pupal stage && adult stage , embryonic stage -- adult stage , embryonic stage | stage 17 " " embryonic/larval proventriculus

, adult brain cortex

,

, larval central nervous system | restricted

, dorsal mesothoracic disc

, oocyte

, ovary

, mesoderm

, embryonic/larval salivary gland

, eye disc

, larval brain

, eye-antennal disc

, embryonic/larval fat body

, morphogenetic furrow

, imaginal disc

, ventral midline

, larval outer optic anlage

, embryonic/larval posterior spiracle | presumptive

, morphogenetic furrow | anterior to

, larval inner optic anlage

,

ubiquitous , nurse cell

, Malpighian tubule | subset

, lamina

, ovary | anlagen

, testis | anlagen

, stomodeum

, proventriculus

, antennal disc

, larval brain | restricted

, adult hindgut | presumptive

, thoracico-abdominal ganglion

, ectoderm

, genital disc

, cephalic furrow

, follicle cell

, embryonic/larval midgut

, labral segment

, adult fat body

, adult foregut | presumptive

, embryonic/larval pharynx

, ventral midline glia | subset

, larval optic lobe

, embryonic telson | presumptive

, embryonic gnathal segment

" " larval stage | third instar , embryonic stage | mid-late , embryonic stage , embryonic stage | late , embryonic stage | mid , embryonic stage | stage 7 , embryonic stage | stage 11-14 " " morphogenetic furrow | posterior to

, lateral proliferation zone

, labral segment

, morphogenetic furrow

, epithelial cell && neuroblast

, muscle attachment site

, apodeme

, embryonic procephalic segment

, embryonic/larval hindgut

, embryonic/larval fat body

, morphogenetic furrow | anterior to

, embryonic/larval visceral muscle

, eye disc

, ectoderm

, imaginal disc

, embryonic mandibular segment

, epithelial cell

, pigment cell

, mesoderm

, ventral midline

, ventral midline glia | subset

, larval outer optic anlage

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,increased cell size,viable,dominant,wound healing defective,mitotic cell cycle defective,somatic clone,non-rescuable maternal effect,visual behavior defective,neuroanatomy defective,increased cell death,decreased cell number,cell polarity defective,female sterile,partially,maternal effect,heat sensitive,planar polarity defective,decreased cell size,lethal - all die before end of pupal stage,some die during pupal stage,cell lethalcell lethal,increased cell number,cell lethal,wild-type,germline clone,cell non-autonomous,semidominant,poor,hyperactive,size defective,conditional,small body,male limited,decreased cell death,learning defective,RU486 conditional,partially lethal - majority die,chemical sensitive,cell size defective,homeotic,chemical resistant,body color defective" "ventral histoblast nest abdominal,spiracular histoblast nest abdominal,adult cuticle,adult spiracle,chaeta,tergite,sternite,heart primordium,midline glial cell,eye,posterior wing margin,adult heart,adult heart muscle,myofilament,cardial cell,,wing vein,wing,embryonic/larval trachea,tracheal lumen,germarium,spectrosome,ommatidium,ventral nerve cord commissure,Malpighian tubule,dorsal closure embryo,extended germ band embryo,embryonic/larval salivary gland,embryonic head,eye disc,RP2 motor neuron,RP2sib neuron,photoreceptor cell,gonad,amnioserosa,embryonic/larval cuticle,embryonic/first instar larval cuticle,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,dorsal appendage,ocellus,macrochaeta,wing disc,submarginal cell,1st posterior cell,neuroblast,hindgut,posterior crossvein,sensory neuron,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,tracheal primordium,presumptive embryonic/larval tracheal system,tracheal branch primordium,ommatidial precursor cluster,dorsal air sac primordium,embryonic/larval posterior spiracle,lch5 neuron,embryonic cardioblast,ventral nerve cord primordium,embryonic/larval oenocyte,anterior crossvein,ventral furrow,egg,embryo,egg chamber,follicle cell,chorion,crossvein,mesothoracic tergum,head,bract,embryonic head epidermis,embryonic optic lobe primordium,optic lobe,embryonic stomatogastric nervous system,brain,corpus cardiacum primordium,Keilin's organ,abdominal ventral denticle belt,genital disc primordium,embryonic optic lobe,embryonic central brain,circumesophageal tract,abdominal lateral longitudinal muscle,abdominal dorsal acute muscle,abdominal ventral acute muscle,embryonic/larval somatic muscle,ventral thoracic disc primordium,embryonic/larval midgut,midgut constriction,endoderm,embryonic/larval muscle system,epidermis,Bolwig organ,anterior supraalar bristle,posterior supraalar bristle,posterior postalar bristle,anterior postalar bristle,anterior dorsocentral bristle,interface glial cell,metathoracic tibial transverse bristle row,prothoracic tibial transverse row bristle,leg,tarsal segment,morphogenetic furrow,spermatocyte,spermatid,spermatocyte cell spectrosome,cyst cell,germline stem cell,pale ommatidium,pretarsus,multidendritic neuron,ventral multidendritic neuron vdaB,cell cycle,embryonic/larval brain,oocyte,adult midgut precursor cell,hypostomal sclerite,cuticle,ventral midline,abdominal ventral monoscolopidial chordotonal organ,abdominal lateral pentascolopidial chordotonal organ,embryonic ventral epidermis,anterior dorsal histoblast nest abdominal,posterior dorsal histoblast nest abdominal,embryonic/larval dorsal trunk,embryonic/larval visceral branch,embryonic segment,intestinal stem cell,glial cell,adult brain,adult eye primordium,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,anterior scutellar bristle,posterior scutellar bristle,A1-7 ventral acute muscle 2,ocellar bristle,filzkorper,stigmatophore,stomatogastric nervous system anlage,enterocyte,adult gut,midgut,wing blade,lamellocyte,cone cell,wing margin,wing hair,larval head,lch5 ligament attachment cell,embryonic epidermis,sensillum basiconicum,sensillum trichodeum,sensillum coeloconicum,optic cartridge,border follicle cell,wing cell,medial longitudinal fascicle,primary pigment cell,secondary pigment cell,tertiary pigment cell,dorsal oblique muscle,dorsal acute muscle,denticle,antenna,retina,eye-antennal disc,tibia,repo,motor neuron,presumptive embryonic/larval peripheral nervous system,fascicle,gastric caecum,embryonic/larval ganglionic branch,lamina monopolar neuron L1-L5,embryonic/larval brain,hemocyte,mesothoracic tibial bract,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,capitellum,wing margin bristle,adult midgut precursor cell-prepupal stage P1,metathoracic tergum" DRSC04613 EK 0.341462121 -0.053537357 -0.125760172 -7.68610776 -5.771602562 -3.325739294 FBgn0000208 Bowed Bowed http://flybase.net/reports/FBgn0000208.html gene Bow 16-Dec-15 2015_12 "visible,dominant" "wing,scutellar bristle,macrochaeta" FBgn0002192 l(3)63Bc lethal (3) 63Bc http://flybase.net/reports/FBgn0002192.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,sterile" FBgn0020655 ArfGAP1 ADP-ribosylation factor GTPase activating protein 1 http://flybase.net/reports/FBgn0020655.html protein_coding_gene "0005525=GTP binding, 0005096=GTPase activator activity" "0043087=regulation of GTPase activity, 0032012=regulation of ARF protein signal transduction" "0005795=Golgi stack, 0005829=cytosol" "arf1GAP, GAP69C, GAP, gap69, Gap69C, GTPase-activating protein 69C, ARF1GAP, Gap69c, ARF1-GAP, dArf1-GAP, i51, CG4237" IPR001164=Arf GTPase activating protein CG4237 16-Dec-15 2015_12 YDL226C(GCS1) WBGene00010500(K02B12.7) ENSXETG00000013313(ARFGAP1) ENSMUSG00000027575(Arfgap1) ENSG00000101199(ARFGAP1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,rhabdomereGMR.PF,eye photoreceptor cell,secondary lobe of embryonic/larval lymph gland | third instar larval stage,posterior signalling centre of lymph gland primary lobe | third instar larval stage,cortical zone of lymph gland primary lobe | third instar larval stage,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage" FBgn0025769 l(3)89Cg lethal (3) 89Cg http://flybase.net/reports/FBgn0025769.html gene l(3)M191 16-Dec-15 2015_12 "lethal,recessive" FBgn0011668 Mst57Da Male-specific RNA 57Da http://flybase.net/reports/FBgn0011668.html "FBgn0002859, FBgn0039377, FBgn0063235" protein_coding_gene "0045297=post-mating behavior, 0018991=oviposition, 0006952=defense response, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0005576=extracellular region" "CG9074, bs30d07.y1, BcDNA:GH19893, Mst57D, mst57D, mst(2)ag-1, mst-1" CG9074 16-Dec-15 2015_12 viable FBgn0014150 dpp::Hsap\BMP4 dpp::Hsap\BMP4 http://flybase.net/reports/FBgn0014150.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0040849 Ir41a Ionotropic receptor 41a http://flybase.net/reports/FBgn0040849.html "FBan0033492, FBgn0053492" protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity" 0009593=detection of chemical stimulus "0016021=integral component of membrane, 0016020=membrane" "DmelIR41a, unnamed, ionotropic receptor 41a, CG33492, IR41a, CG17587" IPR001320=Ionotropic glutamate receptor CG33492 16-Dec-15 2015_12 DRSC04875 K 0.925998956 0.157427659 0.776383293 0.481092686 2.049755131 0.905400238 FBgn0039260 Smg6 Smg6 http://flybase.net/reports/FBgn0039260.html protein_coding_gene "0004540=ribonuclease activity, 0004521=endoribonuclease activity" "0043487=regulation of RNA stability, 0050808=synapse organization, 0007274=neuromuscular synaptic transmission, 0016246=RNA interference, 0035195=gene silencing by miRNA, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 0005829=cytosol "SMG6, CG6369, dSMG6" "IPR002716=PIN domain, IPR018834=DNA/RNA-binding domain, Est1-type, IPR029060=PIN domain-like" CG6369 16-Dec-15 2015_12 YOR166C(SWT1) WBGene00004884(smg-6) ENSMUSG00000038290(Smg6) ENSG00000070366(SMG6) "partially lethal - majority live,lethal,viable,decreased cell number,somatic clone,neurophysiology defective,partially lethal - majority die" "eye,somatic clone" DRSC27703 IK -1.681595537 -0.716966242 -0.685070069 -0.440384161 -1.375684257 -2.085949291 FBgn0037835 CG14687 http://flybase.net/reports/FBgn0037835.html FBgn0062973 protein_coding_gene 0032027=myosin light chain binding BcDNA:RE74890 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000048=IQ motif, EF-hand binding site" CG14687 16-Dec-15 2015_12 WBGene00018214(F39H12.3) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC14910 IE -0.377322513 1.541389552 1.585917986 0.440490847 -1.038253257 -0.442690875 FBgn0264264 CR43764 http://flybase.net/reports/FBgn0264264.html non_protein_coding_gene CR43764 16-Dec-15 2015_12 FBgn0041609 anon-23Ac anon-23Ac http://flybase.net/reports/FBgn0041609.html gene 16-Dec-15 2015_12 FBgn0045043 fs(1)60 female sterile (1) 60 http://flybase.net/reports/FBgn0045043.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "egg,ovary" FBgn0021961 l(2)k10113 lethal (2) k10113 http://flybase.net/reports/FBgn0021961.html FBgn0043374 gene EP1221 16-Dec-15 2015_12 "lethal,recessive,visible" "eye,dorsocentral bristle,scutellar bristle,tormogen cell,embryonic/larval salivary gland" FBgn0031735 CG11029 http://flybase.net/reports/FBgn0031735.html protein_coding_gene 0004622=lysophospholipase activity 0006629=lipid metabolic process "IPR001087=GDSL lipase/esterase, IPR013830=SGNH hydrolase-type esterase domain, IPR008265=Lipase, GDSL, active site" CG11029 16-Dec-15 2015_12 "WBGene00008621(F09C8.1),WBGene00022256(Y73B6BL.37),WBGene00022040(Y65B4BR.1),WBGene00012201(W02B12.1)" ENSXETG00000012248(PLB1) viable FBgn0001400 l(1)2Fc lethal (1) 2Fc http://flybase.net/reports/FBgn0001400.html gene "l(1)N9, HF330, N7, l46, N12, l(1)N12" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone" "ovary,egg,germline clone" FBgn0264327 CR43786 http://flybase.net/reports/FBgn0264327.html non_protein_coding_gene CG43786 CR43786 16-Dec-15 2015_12 FBgn0034783 CG9825 http://flybase.net/reports/FBgn0034783.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG9825 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" viable FBgn0259595 B1267 http://flybase.net/reports/FBgn0259595.html gene 16-Dec-15 2015_12 visible wing FBgn0042633 l(3)S134408b lethal (3) S134408b http://flybase.net/reports/FBgn0042633.html gene "l(3)S134408, 1344/08, l(3)134408" 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0045483 Gr59a Gustatory receptor 59a http://flybase.net/reports/FBgn0045483.html "FBgn0034818, FBgn0050189" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG30189, CG13537, GR59C.1, GR59a" IPR013604=7TM chemoreceptor CG30189 16-Dec-15 2015_12 viable FBgn0028350 l(1)G0173 lethal (1) G0173 http://flybase.net/reports/FBgn0028350.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0003231 ref(2)P refractory to sigma P http://flybase.net/reports/FBgn0003231.html protein_coding_gene 0008270=zinc ion binding "0019058=viral life cycle, 0030382=sperm mitochondrion organization, 0007005=mitochondrion organization" "0005737=cytoplasm, 0005776=autophagic vacuole, 0005634=nucleus" "Ref(2)P, Ref(2)p, p62, ref(2)Pn, SQSTM1, ref(2)Po2, refractaire, refractory to Sigma P, CG10360, ref, sequestosome, sequestosome-1, p63, ref(2)p, Ref2P, ref2p, refractaire(2)Paris" "IPR015940=Ubiquitin-associated domain, IPR009060=UBA-like, IPR000433=Zinc finger, ZZ-type, IPR000270=PB1 domain" CG10360 16-Dec-15 2015_12 WBGene00011737(T12G3.1) ENSXETG00000015913(sqstm1) " adult stage , adult stage | female " ovary

"short lived,stress response defective,locomotor behavior defective,male sterile" "Nebenkern,mitochondrial derivative,indirect flight muscle,mitochondrion,mitochondrial derivativePod2),mitochondrial derivativePod3)" FBgn0061123 l(3)S004019b lethal (3) S004019b http://flybase.net/reports/FBgn0061123.html gene 0040/19 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0051484 CG31484 http://flybase.net/reports/FBgn0051484.html FBgn0037457 protein_coding_gene CG2337 16-Dec-15 2015_12 FBgn0265936 Ada2a::Ada2b http://flybase.net/reports/FBgn0265936.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0036180 CG6091 http://flybase.net/reports/FBgn0036180.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0016579=protein deubiquitination, 0006909=phagocytosis" "Q9VTK7, ped" "IPR003323=OTU domain, IPR003903=Ubiquitin interacting motif, IPR031084=OTU domain-containing protein 5/Otubain-like deubiquitinase 1" CG6091 16-Dec-15 2015_12 "ENSDARG00000059006(otud5a),ENSDARG00000056840(otud5b)" WBGene00015249(B0546.2) ENSMUSG00000031154(Otud5) ENSG00000068308(OTUD5) "viable,visible" trichogen cell FBgn0000539 E(B) Enhancer of Bar http://flybase.net/reports/FBgn0000539.html gene "Exaggeration of Bar, Eb, Intensifier of Bar, I, i" 16-Dec-15 2015_12 "lethal,recessive" FBgn0020637 Lcp65Ag2 Lcp65Ag2 http://flybase.net/reports/FBgn0020637.html "FBgn0002539, FBgn0064908" protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "L[[3]]CP8, Lcp8, CG10534, LCP8, BcDNA:RE01644, chr3L:6106987..6107153, Lcp-g2, DCP8-beta" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG10534 16-Dec-15 2015_12 " pupal stage | 7-13 hr , larval stage , embryonic stage " FBgn0263870 CR43717 http://flybase.net/reports/FBgn0263870.html non_protein_coding_gene CR43717 16-Dec-15 2015_12 FBgn0069317 X-185-37 X-185-37 http://flybase.net/reports/FBgn0069317.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect" FBgn0036749 CG7460 http://flybase.net/reports/FBgn0036749.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR002937=Amine oxidase CG7460 16-Dec-15 2015_12 viable FBgn0024819 Cbf-1 copia binding factor 1 http://flybase.net/reports/FBgn0024819.html gene CBF-1 16-Dec-15 2015_12 FBgn0028695 Rpn1 Regulatory particle non-ATPase 1 http://flybase.net/reports/FBgn0028695.html FBgn0027517 protein_coding_gene "0008270=zinc ion binding, 0030234=enzyme regulator activity" "0008283=cell proliferation, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0000022=mitotic spindle elongation, 0042176=regulation of protein catabolic process, 0007052=mitotic spindle organization" "0000502=proteasome complex, 0008540=proteasome regulatory particle, base subcomplex, 0005838=proteasome regulatory particle" "p97, S2, BcDNA:LD21723, RPN1, CG7762, Rpn1" "IPR002015=Proteasome/cyclosome repeat, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR016643=26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit" CG7762 16-Dec-15 2015_12 ENSDARG00000069531 YHR027C(RPN1) WBGene00004458(rpn-1) ENSXETG00000017286(psmd2) ENSMUSG00000006998(Psmd2) ENSG00000175166(PSMD2) lethal DRSC11274 IEK -2.47427163 -3.052800215 -2.60410134 -0.796476486 3.96492453 0.050076155 FBgn0038506 CG5860 http://flybase.net/reports/FBgn0038506.html protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis FBgn0038506 "IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain, IPR001461=Aspartic peptidase" CG5860 16-Dec-15 2015_12 viable FBgn0060463 l(3)SzB63Cd lethal (3) SzB63Cd http://flybase.net/reports/FBgn0060463.html gene "l(3)S115415a, 1154/15" 16-Dec-15 2015_12 "lethal,recessive" FBgn0052722 CR32722 http://flybase.net/reports/FBgn0052722.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0265532 CR44382 http://flybase.net/reports/FBgn0265532.html non_protein_coding_gene CR44382 16-Dec-15 2015_12 FBgn0259980 ms(2)35Bj male sterile (2) 35Bj http://flybase.net/reports/FBgn0259980.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile FBgn0051975 CG31975 http://flybase.net/reports/FBgn0051975.html FBgn0031223 protein_coding_gene CG18501 "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG31975 16-Dec-15 2015_12 FBgn0030283 CG15198 http://flybase.net/reports/FBgn0030283.html protein_coding_gene CG15198 16-Dec-15 2015_12 viable FBgn0033357 Tom7 Translocase of outer membrane 7 http://flybase.net/reports/FBgn0033357.html FBgn0047336 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0030150=protein import into mitochondrial matrix, 0006626=protein targeting to mitochondrion" 0005742=mitochondrial outer membrane translocase complex "dtom7, BcDNA:AT23266, CG8226" IPR012621=Mitochondrial import receptor subunit TOM7 CG8226 16-Dec-15 2015_12 ENSDARG00000067717(zgc:152998) WBGene00022783(tomm-7) ENSXETG00000027521(TOMM7) ENSMUSG00000028998(Tomm7) viable FBgn0003381 sh-5 short 5 http://flybase.net/reports/FBgn0003381.html gene sh5 16-Dec-15 2015_12 "wing vein L5,wing vein L3" FBgn0033593 Listericin Listericin http://flybase.net/reports/FBgn0033593.html FBgn0062919 protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0051607=defense response to virus, 0061057=peptidoglycan recognition protein signaling pathway, 0050830=defense response to Gram-positive bacterium, 0061059=positive regulation of peptidoglycan recognition protein signaling pathway" 0005615=extracellular space "146991_at, CG9080, BcDNA:RH62530, Listericin" CG9080 16-Dec-15 2015_12 viable FBgn0069935 CG41114 http://flybase.net/reports/FBgn0069935.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038479 CG17477 http://flybase.net/reports/FBgn0038479.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "chymotrypsin-type peptidase, SPH174" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG17477 16-Dec-15 2015_12 viable FBgn0265847 CR44636 http://flybase.net/reports/FBgn0265847.html non_protein_coding_gene CR44636 16-Dec-15 2015_12 FBgn0016890 l(2)39DEo lethal (2) 39DEo http://flybase.net/reports/FBgn0016890.html gene L138 16-Dec-15 2015_12 lethal FBgn0000893 fs(1)M93 female sterile (1) M93 http://flybase.net/reports/FBgn0000893.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0067755 l(1)G0082 lethal (1) G0082 http://flybase.net/reports/FBgn0067755.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0038089 d-cup davis-cup http://flybase.net/reports/FBgn0038089.html protein_coding_gene 0005509=calcium ion binding "CG14387, d-cup, davis-cup" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR028846=Recoverin family" CG14387 16-Dec-15 2015_12 "viable,planar polarity defective" FBgn0261530 nbs nbs http://flybase.net/reports/FBgn0261530.html "FBgn0002220, FBgn0086349, FBgn0026198, FBgn0002218, FBgn0036037" protein_coding_gene "0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0007095=mitotic G2 DNA damage checkpoint, 0042770=signal transduction in response to DNA damage, 0006974=cellular response to DNA damage stimulus, 0045003=double-strand break repair via synthesis-dependent strand annealing, 0051276=chromosome organization, 0031000=response to caffeine, 0016233=telomere capping, 0000723=telomere maintenance" 0030870=Mre11 complex "Nijmegen breakage syndrome, NBS1, Nbs1, Dnbs1, l(3)67BDr, lethal (3) 67BDp, lethal (3) 67BDr, Nbs, l(3)e77A1, CG6754, NBS, 6754, l(3)67BDp" "IPR016592=Nibrin, IPR008984=SMAD/FHA domain, IPR001357=BRCT domain, IPR000253=Forkhead-associated (FHA) domain" CG6754 16-Dec-15 2015_12 ENSDARG00000040303(zgc:194152) ENSMUSG00000028224(Nbn) ENSG00000104320(NBN) DRSC11373 I 1.611432821 0.603789322 0.104101314 0.690760738 0.953776949 0.086898714 FBgn0260081 2L1506 http://flybase.net/reports/FBgn0260081.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0005342 Ring-magnified Ring magnified http://flybase.net/reports/FBgn0005342.html gene "Rm, Ring magnifier" 16-Dec-15 2015_12 FBgn0058251 CG40251 http://flybase.net/reports/FBgn0058251.html protein_coding_gene 16-Dec-15 2015_12 DRSC20820 I 0.41092869 -2.024144012 0.224217532 -0.008181882 FBgn0031418 CG3609 http://flybase.net/reports/FBgn0031418.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process CT12127 "IPR000683=Oxidoreductase, N-terminal, IPR004104=Oxidoreductase, C-terminal, IPR016040=NAD(P)-binding domain" CG3609 16-Dec-15 2015_12 "ENSDARG00000019081(zgc:101723),ENSDARG00000028336(dhdhl)" YML051W(GAL80) ENSXETG00000027480(dhdh) ENSMUSG00000011382(Dhdh) ENSG00000104808(DHDH) "viable,fertile" FBgn0013448 fs(2)ry12 fs(2)ry12 http://flybase.net/reports/FBgn0013448.html gene "fs(2)12, unnamed" 16-Dec-15 2015_12 "female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0066100 MCP-2.s MCP-2.s http://flybase.net/reports/FBgn0066100.html gene 16-Dec-15 2015_12 FBgn0036995 atk artichoke http://flybase.net/reports/FBgn0036995.html protein_coding_gene "0007423=sensory organ development, 0040011=locomotion, 0060271=cilium morphogenesis" "0031012=extracellular matrix, 0005737=cytoplasm" "CT16609, tartan/capricious-like, CG5195" "IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal, IPR001611=Leucine-rich repeat" CG5195 16-Dec-15 2015_12 "ENSMUSG00000052316(Lrrc15),ENSMUSG00000047953(Gp5)" "viable,fertile,locomotor behavior defective,visible" "abdominal lateral pentascolopidial chordotonal organ lch5,mesothoracic tergum" DRSC11418 K -0.126537784 -0.139932838 -0.036318459 0.186485405 -0.337582267 1.578759288 FBgn0039879 Ir100a Ionotropic receptor 100a http://flybase.net/reports/FBgn0039879.html protein_coding_gene 0015276=ligand-gated ion channel activity "0009593=detection of chemical stimulus, 0050909=sensory perception of taste" 0016021=integral component of membrane "ionotropic receptor 100a, CG11575, DmelIR100a, IR100a" CG11575 16-Dec-15 2015_12 viable FBgn0033101 CG9436 http://flybase.net/reports/FBgn0033101.html protein_coding_gene 0004032=alditol:NADP+ 1-oxidoreductase activity 0055114=oxidation-reduction process "IPR023210=NADP-dependent oxidoreductase domain, IPR001395=Aldo/keto reductase, IPR018170=Aldo/keto reductase, conserved site, IPR020471=Aldo/keto reductase subgroup" CG9436 16-Dec-15 2015_12 "YOR120W(GCY1),YDR368W(YPR1)" viable FBgn0086406 BG01084 http://flybase.net/reports/FBgn0086406.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0038087 beat-Va beat-Va http://flybase.net/reports/FBgn0038087.html protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "Beat-Va, beat Va, CG10134" "IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG10134 16-Dec-15 2015_12 "ENSDARG00000068114(si:ch211-89p1.1),ENSDARG00000017320(f11r),ENSDARG00000058996,ENSDARG00000061794(jam3),ENSDARG00000063421" viable FBgn0015504 l(3)95Aa lethal (3) 95Aa http://flybase.net/reports/FBgn0015504.html gene "TnM2, unnamed" 16-Dec-15 2015_12 "lethal,recessive" FBgn0002333 l(3)87Ba lethal (3) 87Ba http://flybase.net/reports/FBgn0002333.html gene "l(3)ck13, ck13" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0259436 C618 http://flybase.net/reports/FBgn0259436.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta" FBgn0266828 CR45290 http://flybase.net/reports/FBgn0266828.html non_protein_coding_gene CR45290 16-Dec-15 2015_12 FBgn0003316 saw sawtooth http://flybase.net/reports/FBgn0003316.html gene 16-Dec-15 2015_12 "viable,fertile,visible,reduced" "wing margin bristle,wing" FBgn0005321 ni2 nicked on chromosome 2 http://flybase.net/reports/FBgn0005321.html gene ni 16-Dec-15 2015_12 "viable,visible,recessive" wing FBgn0263095 CR43363 http://flybase.net/reports/FBgn0263095.html non_protein_coding_gene lincRNA.201 CR43363 16-Dec-15 2015_12 FBgn0029997 CG2258 http://flybase.net/reports/FBgn0029997.html protein_coding_gene 0017022=myosin binding 0006897=endocytosis "IPR018556=Domain of unknown function DUF2013, IPR030125=Protein Ldb17, IPR001452=SH3 domain" CG2258 16-Dec-15 2015_12 ENSMUSG00000032598(Nckipsd) ENSG00000213672(NCKIPSD) "viable,fertile,body color defective" mesothoracic tergum DRSC28795 K 0.452369194 -0.644786765 -0.441374216 0.893063952 -0.244659142 1.519945406 FBgn0024685 l(1)DC711 lethal (1) DC711 http://flybase.net/reports/FBgn0024685.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0011390 l(3)j6A6 lethal (3) j6A6 http://flybase.net/reports/FBgn0011390.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013601 l(3)B7-3-32 lethal (3) B7-3-32 http://flybase.net/reports/FBgn0013601.html gene 16-Dec-15 2015_12 lethal FBgn0262523 l(3)psg6 lethal (3) persistent salivary gland 6 http://flybase.net/reports/FBgn0262523.html gene 0043067=regulation of programmed cell death psg6 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during P-stage" embryonic/larval salivary gland FBgn0058420 CG40420 http://flybase.net/reports/FBgn0058420.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060820 l(3)S052319 lethal (3) S052319 http://flybase.net/reports/FBgn0060820.html gene 0523/19 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0001489 l(1)10Ai lethal (1) 10Ai http://flybase.net/reports/FBgn0001489.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0265945 CR44732 http://flybase.net/reports/FBgn0265945.html non_protein_coding_gene lincRNA.132 CR44732 16-Dec-15 2015_12 FBgn0263872 CR43719 http://flybase.net/reports/FBgn0263872.html non_protein_coding_gene CR43719 16-Dec-15 2015_12 FBgn0026648 l(2)65C2 lethal (2) 65C2 http://flybase.net/reports/FBgn0026648.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0264904 CR44095 http://flybase.net/reports/FBgn0264904.html non_protein_coding_gene CR44095 16-Dec-15 2015_12 FBgn0261961 T:PH-step PH domain of step http://flybase.net/reports/FBgn0261961.html engineered_tag "T:step, PH domain of steppke" 16-Dec-15 2015_12 FBgn0002253 l(3)68Ee lethal (3) 68Ee http://flybase.net/reports/FBgn0002253.html gene "rose-gespleten region interval 15, rsg15, l(3)rsg15" 16-Dec-15 2015_12 lethal FBgn0060385 l(3)S134311b lethal (3) S134311b http://flybase.net/reports/FBgn0060385.html gene 1343/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0001495 l(1)10Bi lethal (1) 10Bi http://flybase.net/reports/FBgn0001495.html gene "l(1)G22, 10Bi" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0061099 l(3)S009512 lethal (3) S009512 http://flybase.net/reports/FBgn0061099.html gene 0095/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0260052 2L3456 http://flybase.net/reports/FBgn0260052.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0037194 CG12353 http://flybase.net/reports/FBgn0037194.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027634 ms(1)268 ms(1)268 http://flybase.net/reports/FBgn0027634.html gene 16-Dec-15 2015_12 male sterile FBgn0035469 CG14977 http://flybase.net/reports/FBgn0035469.html FBgn0061380 protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0032947=protein complex scaffold" "0061462=protein localization to lysosome, 0008361=regulation of cell size, 0032008=positive regulation of TOR signaling, 0071230=cellular response to amino acid stimulus" "0005764=lysosome, 0071986=Ragulator complex" "BcDNA:RH34338, dC7orf59" CG14977 16-Dec-15 2015_12 ENSDARG00000045542(si:dkey-159a18.7) ENSMUSG00000050552(0910001L09Rik) ENSG00000188186(C7orf59) viable FBgn0264911 CG44102 http://flybase.net/reports/FBgn0264911.html protein_coding_gene CG44102 16-Dec-15 2015_12 FBgn0039374 CG17770 http://flybase.net/reports/FBgn0039374.html protein_coding_gene 0005509=calcium ion binding gene2 "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG17770 16-Dec-15 2015_12 viable FBgn0030724 Nipsnap Nipsnap http://flybase.net/reports/FBgn0030724.html protein_coding_gene CG9212 "IPR011008=Dimeric alpha-beta barrel, IPR012577=NIPSNAP" CG9212 16-Dec-15 2015_12 "ENSDARG00000005320(nipsnap1),ENSDARG00000007264(gbas)" WBGene00019301(K02D10.1) "ENSXETG00000016420(nipsnap1),ENSXETG00000010086(GBAS)" "ENSMUSG00000034285(Nipsnap1),ENSMUSG00000029432(Gbas)" "ENSG00000184117(NIPSNAP1),ENSG00000146729(GBAS)" viable FBgn0015442 l(1)7Ci lethal (1) 7Ci http://flybase.net/reports/FBgn0015442.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000537 eay early http://flybase.net/reports/FBgn0000537.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal,maternal effect" FBgn0025142 ms(3)A5 ms(3)A5 http://flybase.net/reports/FBgn0025142.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0265099 CR44204 http://flybase.net/reports/FBgn0265099.html non_protein_coding_gene CG44204 CR44204 16-Dec-15 2015_12 FBgn0002881 mus105 mutagen-sensitive 105 http://flybase.net/reports/FBgn0002881.html gene "l(1)dd1, mus(1)105, l(1)d.deg-1, lethal(1)discs degenerate, mus-105, l(1)d deg-1" 16-Dec-15 2015_12 "mitotic cell cycle defective,recessive,lethal,cell lethal,germline clone,chemical sensitive,radiation sensitive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "mitosis & nuclear chromosome,imaginal disc,cell cycle" FBgn0035032 ATPsynF "ATP synthase, subunit F" http://flybase.net/reports/FBgn0035032.html FBgn0027681 protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0046331=lateral inhibition, 0015992=proton transport" "0005739=mitochondrion, 0005811=lipid particle, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATP synthase F chain, ATP synthase, CG4692, ATP synthase f chain, F0/F1 ATP synthase F, ATPK, anon-EST:Posey45" "IPR019344=Mitochondrial F1-F0 ATP synthase subunit F, predicted" CG4692 16-Dec-15 2015_12 ENSDARG00000037867(LOC402883) ENSXETG00000009893(ATP5J2) ENSMUSG00000038690(Atp5j2) ENSG00000160916 "viable,visible" "chaeta,trichogen cell" FBgn0061172 fra::unc-5 fra::unc-5 http://flybase.net/reports/FBgn0061172.html engineered_fusion_gene 16-Dec-15 2015_12 neuroanatomy defective "anterior commissure,posterior commissure,intersegmental nerve" FBgn0262480 CG43070 http://flybase.net/reports/FBgn0262480.html protein_coding_gene lincRNA.347 CG43070 16-Dec-15 2015_12 FBgn0266838 CR45300 http://flybase.net/reports/FBgn0266838.html non_protein_coding_gene CR45300 16-Dec-15 2015_12 FBgn0028965 A16 A16 http://flybase.net/reports/FBgn0028965.html FBgn0032468 protein_coding_gene 0008157=protein phosphatase 1 binding 0000164=protein phosphatase type 1 complex CG9933 IPR000953=Chromo/chromo shadow domain CG9933 16-Dec-15 2015_12 "viable,fertile" DRSC03276 K -0.349950004 -0.699962587 0.450254212 -0.549468308 1.518266661 0.696612139 FBgn0028194 l(3)S022378 lethal (3) S022378 http://flybase.net/reports/FBgn0028194.html gene 0223/78 16-Dec-15 2015_12 "lethal,recessive" FBgn0032833 COX4 Cytochrome c oxidase subunit 4 http://flybase.net/reports/FBgn0032833.html protein_coding_gene 0004129=cytochrome-c oxidase activity "0000278=mitotic cell cycle, 0007030=Golgi organization, 0008283=cell proliferation, 0007406=negative regulation of neuroblast proliferation, 0006123=mitochondrial electron transport, cytochrome c to oxygen" "0005751=mitochondrial respiratory chain complex IV, 0005739=mitochondrion, 0005811=lipid particle" "COX, Cytochrome c oxidase IV, CX42, COX IV, CoxIV, CG10664, Cytochrome c oxidase Polypeptide IV, CoIV, Cytochrome c oxidase subunit IV, cytochrome c oxidase, Cytochrome c oxidase Subunit IV, IV, Subunit IV, CcO IV, COXIV, dCOX-IV, CX41, cox4" "IPR013288=Cytochrome c oxidase subunit IV, IPR004203=Cytochrome c oxidase subunit IV family" CG10664 16-Dec-15 2015_12 "ENSDARG00000032970(cox4i1),ENSDARG00000022509(zgc:73355),ENSDARG00000012388(LOC402880)" WBGene00012354(W09C5.8) "ENSXETG00000004473(cox4i1),ENSXETG00000027592(COX4I2)" "ENSMUSG00000031818(Cox4i1),ENSMUSG00000009876(Cox4i2)" "ENSG00000131055(COX4I2),ENSG00000131143(COX4I1)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC23915 EK -1.212097348 -0.160552146 -1.865078656 -0.066512014 1.674157714 0.717441295 FBgn0042158 CG18835 http://flybase.net/reports/FBgn0042158.html protein_coding_gene 16-Dec-15 2015_12 FBgn0086372 lap like-AP180 http://flybase.net/reports/FBgn0086372.html "FBgn0026210, FBgn0062670, FBgn0011467, FBgn0026062, FBgn0047251" protein_coding_gene "0005545=1-phosphatidylinositol binding, 0030276=clathrin binding" "0016183=synaptic vesicle coating, 2000370=positive regulation of clathrin-mediated endocytosis, 0042331=phototaxis, 0048489=synaptic vesicle transport, 0048268=clathrin coat assembly, 0007268=synaptic transmission, 0007269=neurotransmitter secretion, 0006898=receptor-mediated endocytosis, 0048488=synaptic vesicle endocytosis, 0007270=neuron-neuron synaptic transmission" "0008021=synaptic vesicle, 0030131=clathrin adaptor complex, 0030136=clathrin-coated vesicle, 0005905=coated pit" "Like-AP180, like-AP180, LAP, saisoog, EP(3)3060, lap/AP180, complementation group 12, AP180, EP3060, dAP-3, like AP180, l(3)neo34, BcDNA:GM10787, CG2520, Lap, sig" "IPR014712=Phosphoinositide-binding clathrin adaptor, domain 2, IPR008942=ENTH/VHS, IPR011417=AP180 N-terminal homology (ANTH) domain, IPR013809=ENTH domain" CG2520 16-Dec-15 2015_12 "ENSDARG00000014137(picalml),ENSDARG00000012866(picalm),ENSDARG00000029170(LOC565799)" "YGR241C(YAP1802),YHR161C(YAP1801)" WBGene00006751(unc-11) ENSXETG00000001528(PICALM) "ENSMUSG00000039361(Picalm),ENSMUSG00000033419(Snap91)" "ENSG00000073921(PICALM),ENSG00000065609(SNAP91)" embryonic stage " embryonic central nervous system

, embryonic peripheral nervous system

, garland cell

" larval stage " neuromuscular junction

, bouton

" FBgn0266004 CR44778 http://flybase.net/reports/FBgn0266004.html non_protein_coding_gene CR44778 16-Dec-15 2015_12 FBgn0023527 CG3071 http://flybase.net/reports/FBgn0023527.html protein_coding_gene 0030515=snoRNA binding "0045943=positive regulation of transcription from RNA polymerase I promoter, 0000462=maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0009267=cellular response to starvation" "0005730=nucleolus, 0034455=t-UTP complex" EG:25E8.3 "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR018983=U3 small nucleolar RNA-associated protein 15, C-terminal" CG3071 16-Dec-15 2015_12 ENSDARG00000002720(utp15) YMR093W(UTP15) WBGene00021276(Y23H5B.5) ENSXETG00000016821(BC084500.1) ENSMUSG00000041747(Utp15) ENSG00000164338(UTP15) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052814 CG32814 http://flybase.net/reports/FBgn0052814.html protein_coding_gene CG32814 16-Dec-15 2015_12 FBgn0002326 l(3)86Fe lethal (3) 86Fe http://flybase.net/reports/FBgn0002326.html gene "l(3)ck5, ck5" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0267181 CR45621 http://flybase.net/reports/FBgn0267181.html non_protein_coding_gene CR45621 16-Dec-15 2015_12 FBgn0267079 CR45523 http://flybase.net/reports/FBgn0267079.html non_protein_coding_gene CR45523 16-Dec-15 2015_12 FBgn0029024 l(3)77ABh lethal (3) 77ABh http://flybase.net/reports/FBgn0029024.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0004401 Pep Protein on ecdysone puffs http://flybase.net/reports/FBgn0004401.html FBgn0036743 protein_coding_gene "0003677=DNA binding, 0003697=single-stranded DNA binding, 0046872=metal ion binding, 0003727=single-stranded RNA binding" "0000398=mRNA splicing, via spliceosome, 0048024=regulation of mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005703=polytene chromosome puff, 0005634=nucleus, 0005875=microtubule associated complex" "PEP, pep, PEP/X4, 74F gene, X4/PEP, p100, CG6143" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG6143 16-Dec-15 2015_12 ENSDARG00000006895 embryonic stage -- adult stage viable FBgn0069420 JJF095 JJF095 http://flybase.net/reports/FBgn0069420.html gene 16-Dec-15 2015_12 stress response defective FBgn0263406 CR43452 http://flybase.net/reports/FBgn0263406.html non_protein_coding_gene CR43452 16-Dec-15 2015_12 FBgn0010732 l(3)00864 lethal (3) 00864 http://flybase.net/reports/FBgn0010732.html FBgn0011494 gene l(3)rG084 16-Dec-15 2015_12 "lethal,recessive" FBgn0038294 Mf Myofilin http://flybase.net/reports/FBgn0038294.html FBgn0064959 protein_coding_gene "0022416=chaeta development, 0030241=skeletal muscle myosin thick filament assembly, 0035220=wing disc development" 0031672=A band "CG6803, Zeelin1, z1, Zeelin, myofilin, zeelin1, BcDNA:GH23305, DmMf" CG6803 16-Dec-15 2015_12 viable FBgn0260965 CG42588 http://flybase.net/reports/FBgn0260965.html "FBgn0036315, FBgn0054017, FBgn0082890, FBgn0052108, FBgn0062863" protein_coding_gene 0022008=neurogenesis "CG34017, CG32108, BcDNA:SD20456, unnamed, CG11008, BP1016" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG42588 16-Dec-15 2015_12 ENSXETG00000020964(GTF3C2) FBgn0038697 CG3581 http://flybase.net/reports/FBgn0038697.html protein_coding_gene IPR006623=Testicular haploid expressed repeat CG3581 16-Dec-15 2015_12 viable FBgn0065850 l(2)SH0307 lethal (2) SH0307 http://flybase.net/reports/FBgn0065850.html gene l(2)SH2 0307 16-Dec-15 2015_12 "lethal,recessive" FBgn0001580 l(1)AL2 lethal (1) AL2 http://flybase.net/reports/FBgn0001580.html gene 16-Dec-15 2015_12 "lethal,short lived" FBgn0038389 CG5516 http://flybase.net/reports/FBgn0038389.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "IPR001878=Zinc finger, CCHC-type" CG5516 16-Dec-15 2015_12 ENSXETG00000004171(ZCCHC10) ENSMUSG00000018239(Zcchc10) ENSG00000155329(ZCCHC10) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0005209 l(3)LVML lethal (3) LVML http://flybase.net/reports/FBgn0005209.html gene 16-Dec-15 2015_12 lethal FBgn0011148 l(1)Q224 lethal (1) Q224 http://flybase.net/reports/FBgn0011148.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0259791 bora aurora borealis http://flybase.net/reports/FBgn0259791.html "FBgn0064189, FBgn0036800" protein_coding_gene 0005515=protein binding "0032147=activation of protein kinase activity, 0007422=peripheral nervous system development, 0045167=asymmetric protein localization involved in cell fate determination" "0005634=nucleus, 0005737=cytoplasm" "CG6897, borealis" IPR023252=Aurora borealis protein CG6897 16-Dec-15 2015_12 WBGene00010198(spat-1) ENSMUSG00000022070(6720463M24Rik) ENSG00000136122(BORA) FBgn0040527 CG11603 http://flybase.net/reports/FBgn0040527.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065654 l(2)SH0727 lethal (2) SH0727 http://flybase.net/reports/FBgn0065654.html gene l(2)SH2 0727 16-Dec-15 2015_12 "lethal,recessive" FBgn0060420 l(3)S128306 lethal (3) S128306 http://flybase.net/reports/FBgn0060420.html gene 1283/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266035 CR44800 http://flybase.net/reports/FBgn0266035.html non_protein_coding_gene lincRNA.71 CR44800 16-Dec-15 2015_12 FBgn0067868 Mod(Prat:bw)3-7 Mod(Prat:bw)3-7 http://flybase.net/reports/FBgn0067868.html gene Mod-3-7 16-Dec-15 2015_12 FBgn0265081 CR44192 http://flybase.net/reports/FBgn0265081.html non_protein_coding_gene CR44192 16-Dec-15 2015_12 FBgn0259661 B0295 http://flybase.net/reports/FBgn0259661.html gene 16-Dec-15 2015_12 lethal FBgn0038606 CG15803 http://flybase.net/reports/FBgn0038606.html protein_coding_gene lincRNA.804 IPR001478=PDZ domain CG15803 16-Dec-15 2015_12 ENSXETG00000011680(LNX1) "ENSG00000172349(IL16),ENSG00000133401(PDZD2)" viable FBgn0260816 EY13010 http://flybase.net/reports/FBgn0260816.html gene 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0067636 146y 146y http://flybase.net/reports/FBgn0067636.html gene 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0024540 l(3)L2049 lethal (3) L2049 http://flybase.net/reports/FBgn0024540.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065390 l(2)SH1630 lethal (2) SH1630 http://flybase.net/reports/FBgn0065390.html gene l(2)SH2 1630 16-Dec-15 2015_12 "lethal,recessive" FBgn0052437 CG32437 http://flybase.net/reports/FBgn0052437.html FBgn0037079 protein_coding_gene CG5051 CG32437 16-Dec-15 2015_12 FBgn0036762 CG7430 http://flybase.net/reports/FBgn0036762.html protein_coding_gene "0004148=dihydrolipoyl dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" "0006546=glycine catabolic process, 0045454=cell redox homeostasis, 0006099=tricarboxylic acid cycle, 0006748=lipoamide metabolic process" "0005811=lipid particle, 0005960=glycine cleavage complex, 0005947=mitochondrial alpha-ketoglutarate dehydrogenase complex" "alpha-ketoglutarate dehydrogenase E3 subunit, E3, Pyruvate dehydrogenase E3 subunit" "IPR012999=Pyridine nucleotide-disulphide oxidoreductase, class I, active site, IPR006258=Dihydrolipoamide dehydrogenase, IPR004099=Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR016156=FAD/NAD-linked reductase, dimerisation domain, IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain" CG7430 16-Dec-15 2015_12 ENSDARG00000008785(dldh) YFL018C(LPD1) WBGene00010794(LLC1.3) ENSXETG00000012269(DLD) ENSMUSG00000020664(Dld) ENSG00000091140(DLD) viable FBgn0085383 CG34354 http://flybase.net/reports/FBgn0085383.html "FBgn0039571, FBgn0039573, FBgn0039572" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" "CG4787, CG12425, CG12852, cg4787" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG34354 16-Dec-15 2015_12 YNL016W(PUB1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032025 CG7778 http://flybase.net/reports/FBgn0032025.html protein_coding_gene CG7778 16-Dec-15 2015_12 "viable,fertile" FBgn0033322 CG8584 http://flybase.net/reports/FBgn0033322.html FBgn0045780 protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation 0005737=cytoplasm "BEST:LP01468, 19527701" "IPR023214=HAD-like domain, IPR011948=Dullard phosphatase domain, eukaryotic, IPR004274=FCP1 homology domain" CG8584 16-Dec-15 2015_12 viable FBgn0264599 CR43948 http://flybase.net/reports/FBgn0264599.html non_protein_coding_gene CR43948 16-Dec-15 2015_12 FBgn0262033 CR42844 http://flybase.net/reports/FBgn0262033.html non_protein_coding_gene "lincRNA.85, CG42844" CR42844 16-Dec-15 2015_12 FBgn0052652 CR32652 http://flybase.net/reports/FBgn0052652.html "FBgn0045133, FBgn0045144, FBgn0045164, FBgn0045169, FBgn0045191, FBgn0045197, FBgn0045276, FBgn0045299, FBgn0045317, FBgn0045366, FBgn0045430, FBgn0046056" non_protein_coding_gene "bs27g02.y1, bs30c01.y1, bs02c02.y1, bs27e03.y1, NEST:bs30c01, bs14f06.y1, NEST:bs16e05, NEST:bs24h05, NEST:bs14f06, NEST:bs02c02, bs14d08.y1, bs16e05.y1, bs13e06.y1, NEST:bs27e03, CG32652, NEST:bs08g03, NEST:bs29d03, mdcds_53609, NEST:bs13e06, bs08g03.y1, NEST:bs23h05, NEST:bs27g02, bs24h05.y1" CR32652 16-Dec-15 2015_12 viable FBgn0259418 C343 http://flybase.net/reports/FBgn0259418.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0028568 robl60C robl60C http://flybase.net/reports/FBgn0028568.html gene 16-Dec-15 2015_12 FBgn0051410 Npc2e Niemann-Pick type C-2e http://flybase.net/reports/FBgn0051410.html FBgn0040540 protein_coding_gene "0030882=lipid antigen binding, 0001530=lipopolysaccharide binding, 0032934=sterol binding, 0042834=peptidoglycan binding, 0070891=lipoteichoic acid binding" "0015918=sterol transport, 0061057=peptidoglycan recognition protein signaling pathway" 0005615=extracellular space "CG31410, npc2e, CG3928" "IPR003172=MD-2-related lipid-recognition domain, IPR014756=Immunoglobulin E-set" CG31410 16-Dec-15 2015_12 viable FBgn0013983 imd immune deficiency http://flybase.net/reports/FBgn0013983.html "FBgn0034344, FBgn0046434" protein_coding_gene "0070513=death domain binding, 0005515=protein binding" "0006955=immune response, 0045087=innate immune response, 0035556=intracellular signal transduction, 0061057=peptidoglycan recognition protein signaling pathway, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0006959=humoral immune response, 0002230=positive regulation of defense response to virus by host, 0009617=response to bacterium, 0006952=defense response, 0019731=antibacterial humoral response, 0007399=nervous system development, 0019730=antimicrobial humoral response, 0042742=defense response to bacterium, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0007165=signal transduction" 0005622=intracellular "IMD, immune deficient, Imd, anon-WO0172774.166, Immune deficiency, BG5, CG5576, shadok, Immunodeficiency, unnamed" "IPR011029=Death-like domain, IPR000488=Death domain" CG5576 16-Dec-15 2015_12 "short lived,immune response defective,viable,fertile,radiation resistant,recessive,increased cell death,radiation sensitive,lethal - all die before end of larval stage,some die during larval stage" embryonic/larval fat body FBgn0085481 CG34452 http://flybase.net/reports/FBgn0085481.html "FBgn0082857, FBgn0053999" protein_coding_gene 0008378=galactosyltransferase activity 0006486=protein glycosylation 0016020=membrane "CG33999, BP1049" IPR003378=Fringe-like CG34452 16-Dec-15 2015_12 FBgn0004174 Mst84Dc Male-specific RNA 84Dc http://flybase.net/reports/FBgn0004174.html protein_coding_gene "0007288=sperm axoneme assembly, 0007283=spermatogenesis" "Mst, Mst87D, Mst ORF, Mstprox, mst(3)gl-3, Mst84, Mst84D, CG17945" IPR005634=Male specific sperm protein CG17945 16-Dec-15 2015_12 viable FBgn0060998 l(3)S027022 lethal (3) S027022 http://flybase.net/reports/FBgn0060998.html gene 0270/22 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040130 l(2)22Ai lethal (2) 22Ai http://flybase.net/reports/FBgn0040130.html gene D 16-Dec-15 2015_12 "lethal,recessive" FBgn0040858 CG11359 http://flybase.net/reports/FBgn0040858.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032268 CG6138 http://flybase.net/reports/FBgn0032268.html FBgn0063711 protein_coding_gene BcDNA:AT25107 CG6138 16-Dec-15 2015_12 viable FBgn0019925 Surf4 Surfeit 4 http://flybase.net/reports/FBgn0019925.html protein_coding_gene 0046331=lateral inhibition "0016021=integral component of membrane, 0045169=fusome, 0005789=endoplasmic reticulum membrane, 0012505=endomembrane system" "CG6202, Surf-4, SURF-4" IPR002995=Surfeit locus 4 CG6202 16-Dec-15 2015_12 "ENSDARG00000002702,ENSDARG00000035131(surf4l)" YGR284C(ERV29) WBGene00004788(sft-4) ENSXETG00000005583(BC081286.1) ENSMUSG00000014867(Surf4) ENSG00000148248(SURF4) "lethal,viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0005026 drp droop wings http://flybase.net/reports/FBgn0005026.html gene 16-Dec-15 2015_12 "visible,recessive" wing FBgn0061010 l(3)S026220b lethal (3) S026220b http://flybase.net/reports/FBgn0061010.html gene 0262/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0002489 l(3)SG49 lethal (3) SG49 http://flybase.net/reports/FBgn0002489.html FBgn0004726 gene l(3)ds8 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0004216 l(3)84Fd lethal (3) 84Fd http://flybase.net/reports/FBgn0004216.html gene 16-Dec-15 2015_12 lethal FBgn0058085 CG40085 http://flybase.net/reports/FBgn0058085.html FBan0040085 protein_coding_gene 16-Dec-15 2015_12 FBgn0013518 l(1)rp1 lethal (1) rp1 http://flybase.net/reports/FBgn0013518.html gene 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0250737 l(3)S091911 lethal (3) S091911 http://flybase.net/reports/FBgn0250737.html gene l(3)s091911 16-Dec-15 2015_12 lethal FBgn0267804 CR46129 http://flybase.net/reports/FBgn0267804.html non_protein_coding_gene CR46129 16-Dec-15 2015_12 FBgn0037742 Rpt3R Regulatory particle triple-A ATPase 3-related http://flybase.net/reports/FBgn0037742.html protein_coding_gene "0016887=ATPase activity, 0016787=hydrolase activity, 0005524=ATP binding" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005737=cytoplasm, 0008540=proteasome regulatory particle, base subcomplex, 0000502=proteasome complex" "DmCG9475, Rpt3R, S6, CG9475, 9475, Dm_Rpt3b" "IPR005937=26S proteasome subunit P45, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR001270=ClpA/B family" CG9475 16-Dec-15 2015_12 YDR394W(RPT3) WBGene00004503(rpt-3) DRSC16501 IEK -0.672692436 -2.138248117 -2.280806853 -0.602518049 2.231512421 1.310186938 FBgn0035094 CG9380 http://flybase.net/reports/FBgn0035094.html protein_coding_gene 0008745=N-acetylmuramoyl-L-alanine amidase activity 0009253=peptidoglycan catabolic process IPR015510=Peptidoglycan recognition protein CG9380 16-Dec-15 2015_12 viable FBgn0039598 aqrs aquarius http://flybase.net/reports/FBgn0039598.html protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0046693=sperm storage, 0045434=negative regulation of female receptivity, post-mating, 0006508=proteolysis" 0005615=extracellular space CG14061 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG14061 16-Dec-15 2015_12 "mating behavior defective,female limited,female semi-fertile" seminal receptacle FBgn0031638 CG11927 http://flybase.net/reports/FBgn0031638.html protein_coding_gene CG11927 16-Dec-15 2015_12 "viable,fertile" DRSC00337 K 0.492620194 -0.700530618 0.158035351 -0.285140326 0.659951645 2.688319159 FBgn0265801 CR44590 http://flybase.net/reports/FBgn0265801.html non_protein_coding_gene CR44590 16-Dec-15 2015_12 FBgn0017631 Eig17B Eig17B http://flybase.net/reports/FBgn0017631.html gene "Eig17-2, Ecdysone-induced gene 17B" 16-Dec-15 2015_12 FBgn0027992 l(3)S126705 lethal (3) S126705 http://flybase.net/reports/FBgn0027992.html gene "1267/05, 0428/25" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0023121 anon-10Am anon-10Am http://flybase.net/reports/FBgn0023121.html gene 5 16-Dec-15 2015_12 FBgn0262414 mir-4 mir-4 stem loop http://flybase.net/reports/FBgn0262414.html "FBgn0046821, FBgn0082173, FBgn0262254" miRNA_gene "CR33561, 4, mir-4, miR-4, mir-4S, CR33038, CR42961, mir-4*" CR42961 16-Dec-15 2015_12 " larval stage | first instar , embryonic stage " visible "chaeta,ectopic,wing disc" FBgn0036717 CG13731 http://flybase.net/reports/FBgn0036717.html protein_coding_gene CG13731 16-Dec-15 2015_12 FBgn0263951 BG00890 http://flybase.net/reports/FBgn0263951.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0261617 nej nejire http://flybase.net/reports/FBgn0261617.html "FBgn0027307, FBgn0040152, FBgn0030150, FBgn0015624, FBgn0030149, FBgn0066809, FBgn0028319" protein_coding_gene "0043993=histone acetyltransferase activity (H3-K18 specific), 0003713=transcription coactivator activity, 0008140=cAMP response element binding protein binding, 0042800=histone methyltransferase activity (H3-K4 specific), 0004402=histone acetyltransferase activity, 0005515=protein binding, 1990226=histone methyltransferase binding, 0008134=transcription factor binding, 0044017=histone acetyltransferase activity (H3-K27 specific), 0008270=zinc ion binding" "0008347=glial cell migration, 0007088=regulation of mitotic nuclear division, 0048749=compound eye development, 0001745=compound eye morphogenesis, 0045475=locomotor rhythm, 0032922=circadian regulation of gene expression, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007224=smoothened signaling pathway, 0043974=histone H3-K27 acetylation, 0007416=synapse assembly, 0000076=DNA replication checkpoint, 0043983=histone H4-K12 acetylation, 0040040=thermosensory behavior, 0016573=histone acetylation, 0007269=neurotransmitter secretion, 0022008=neurogenesis, 0007464=R3/R4 cell fate commitment, 0051568=histone H3-K4 methylation, 0016055=Wnt signaling pathway, 0030097=hemopoiesis, 0043971=histone H3-K18 acetylation, 0043982=histone H4-K8 acetylation, 0045466=R7 cell differentiation" "0005634=nucleus, 0000123=histone acetyltransferase complex, 0043234=protein complex, 0035097=histone methyltransferase complex, 0005654=nucleoplasm, 0005700=polytene chromosome" "lethal (1) G0470, Nejire, dKAT3, nej CBP, CBP_, p300, l(1)G0112, CREB-binding protein, protein, dCBP, l(1)G0350, CBP/p300, cbp, Drosophila CREB-binding, dmCBP, anon-WO0147981.11, anon-WO03040301.89, Cyclic AMP Response Element Binding protein, CBP, CBP/Nejire, lethal (1) G0350, lethal (1) G0112, p300/CBP, CG15319, l(1)G0470, Drosophila CREB-binding protein, Crbp, CG15321, CREB binding protein, Nej, Cbp" "IPR003101=Coactivator CBP, KIX domain, IPR000433=Zinc finger, ZZ-type, IPR013178=Histone acetyltransferase Rtt109/CBP, IPR000197=Zinc finger, TAZ-type, IPR018359=Bromodomain, conserved site, IPR031162=CBP/p300-type histone acetyltransferase domain, IPR010303=Domain of unknown function DUF902, CREBbp, IPR009110=Nuclear receptor coactivator, interlocking, IPR014744=Nuclear receptor coactivator, CREB-bp-like, interlocking, IPR019786=Zinc finger, PHD-type, conserved site, IPR001487=Bromodomain" CG15319 16-Dec-15 2015_12 "ENSDARG00000062380,ENSDARG00000061308(crebbpa),ENSDARG00000063102" WBGene00000366(cbp-1) ENSXETG00000010317(CREBBP) "ENSMUSG00000055024(Ep300),ENSMUSG00000022521(Crebbp)" "ENSG00000100393(EP300),ENSG00000005339(CREBBP)" embryonic stage | cellular blastoderm """DRSC18801, DRSC18006"" " IEK FBgn0003033 pal paternal loss inducer http://flybase.net/reports/FBgn0003033.html gene 0007140=male meiosis "paternal loss, mei-W5" 16-Dec-15 2015_12 "male fertile,mitotic cell cycle defective,meiotic cell cycle defective,male,recessive" nuclear chromosome | male FBgn0060898 l(3)S044221a lethal (3) S044221a http://flybase.net/reports/FBgn0060898.html gene 0442/21 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0037876 CG4820 http://flybase.net/reports/FBgn0037876.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG4820 16-Dec-15 2015_12 viable FBgn0028514 CG4793 http://flybase.net/reports/FBgn0028514.html "FBgn0027849, FBgn0032578" protein_coding_gene 0004252=serine-type endopeptidase activity "0035208=positive regulation of hemocyte proliferation, 0006508=proteolysis" "SPH208, BG:DS07486.3" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG4793 16-Dec-15 2015_12 viable FBgn0259578 B1513 http://flybase.net/reports/FBgn0259578.html gene 16-Dec-15 2015_12 visible "wing,wing vein,macrochaeta" FBgn0082367 EP3582 EP3582 http://flybase.net/reports/FBgn0082367.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0041747 l(1)em2 lethal (1) em2 http://flybase.net/reports/FBgn0041747.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065881 l(2)SH0235 lethal (2) SH0235 http://flybase.net/reports/FBgn0065881.html gene l(2)SH2 0235 16-Dec-15 2015_12 "lethal,recessive" FBgn0013551 l(3)ry103 lethal (3) ry103 http://flybase.net/reports/FBgn0013551.html "FBgn0013572, FBgn0014321" gene "l(3)82AB, l(3)ry147, l(3)103" 16-Dec-15 2015_12 "lethal,recessive" FBgn0060367 l(3)S138111 lethal (3) S138111 http://flybase.net/reports/FBgn0060367.html gene 1381/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0024199 pinto pinto http://flybase.net/reports/FBgn0024199.html gene 0007391=dorsal closure pin 16-Dec-15 2015_12 FBgn0004527 l(4)102CDj lethal (4) 102CDj http://flybase.net/reports/FBgn0004527.html gene "l(4)ST-4, l(4)15, lethal(4) Salt Lake City-1, lethal(4) Solway, Tennessee-4, l(4)CDj, l(4)SLC-1, l(4)MW-1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,visible" "male genitalia,wing,wing vein" FBgn0019905 anon-14Be anon-14Be http://flybase.net/reports/FBgn0019905.html gene ORF 16-Dec-15 2015_12 FBgn0260238 CG42512 http://flybase.net/reports/FBgn0260238.html FBgn0260433 protein_coding_gene "CG42528, Dromel_CG32573_FBtr0074315_uORF" CG42512 16-Dec-15 2015_12 FBgn0085612 CR41320 http://flybase.net/reports/FBgn0085612.html FBan0041320 pseudogene_attribute CG41320 CR41320 16-Dec-15 2015_12 FBgn0264253 Send2 Spermathecal endopeptidase 2 http://flybase.net/reports/FBgn0264253.html "FBgn0264076, FBgn0028917" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "DS01068.10, BG:DS01068.10, CG18125, SPH190" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG18125 16-Dec-15 2015_12 FBgn0031345 CG18132 http://flybase.net/reports/FBgn0031345.html protein_coding_gene 0045454=cell redox homeostasis "IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG18132 16-Dec-15 2015_12 viable DRSC00518 K 0.671478908 -0.878700261 0.163511173 0.166270327 1.802049636 0.300551271 FBgn0065160 l(3)SH044 lethal (3) SH044 http://flybase.net/reports/FBgn0065160.html gene l(2)SH3 044 16-Dec-15 2015_12 "lethal,recessive" FBgn0005036 E(scalloped) Enhancer of scalloped http://flybase.net/reports/FBgn0005036.html gene E(sd) 16-Dec-15 2015_12 FBgn0040800 CG13052 http://flybase.net/reports/FBgn0040800.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267129 CR45569 http://flybase.net/reports/FBgn0267129.html non_protein_coding_gene CR45569 16-Dec-15 2015_12 FBgn0082342 HM530 HM530 http://flybase.net/reports/FBgn0082342.html gene 16-Dec-15 2015_12 FBgn0036367 CG10116 http://flybase.net/reports/FBgn0036367.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "IPR000734=Triacylglycerol lipase family, IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold" CG10116 16-Dec-15 2015_12 viable FBgn0013653 ms(2)LY1 ms(2)LY1 http://flybase.net/reports/FBgn0013653.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0261803 CG42749 http://flybase.net/reports/FBgn0261803.html "FBgn0040913, FBgn0029749" protein_coding_gene 0019028=viral capsid "CG15786, CG15785" "IPR004302=Chitin-binding, domain 3" CG42749 16-Dec-15 2015_12 FBgn0036128 Elo68ë_ Elongase 68ë_ http://flybase.net/reports/FBgn0036128.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane "elo68beta, Elo68beta, CG11801" IPR002076=ELO family CG11801 16-Dec-15 2015_12 "ENSDARG00000027495(elovl4b),ENSDARG00000006773(elovl4a),ENSDARG00000057365(zgc:112263),ENSDARG00000068551(zgc:153394)" "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" ENSMUSG00000032262(Elovl4) ENSG00000118402(ELOVL4) viable FBgn0022008 l(2)k09216 lethal (2) k09216 http://flybase.net/reports/FBgn0022008.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050005 GstT2 Glutathione S transferase T2 http://flybase.net/reports/FBgn0050005.html FBgn0033436 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "CG12930A, CG12930, CG30005, gstt2, GSTT2" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal" CG30005 16-Dec-15 2015_12 "ENSMUSG00000001663(Gstt1),ENSMUSG00000001665(Gstt3),ENSMUSG00000009093(Gstt4),ENSMUSG00000033318(Gstt2)" viable DRSC06244 E -0.287351328 0.204748138 1.611984003 -0.056901396 -0.242746207 0.869418729 FBgn0028847 CG9014 http://flybase.net/reports/FBgn0028847.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding, 0016881=acid-amino acid ligase activity, 0031386=protein tag" 0000209=protein polyubiquitination "DS08249.3, BG:DS08249.3" "IPR013323=SIAH-type domain, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR008974=TRAF-like, IPR015036=USP8 interacting, IPR018957=Zinc finger, C3HC4 RING-type" CG9014 16-Dec-15 2015_12 viable FBgn0010407 Ror Ror http://flybase.net/reports/FBgn0010407.html FBgn0022797 protein_coding_gene "0005030=neurotrophin receptor activity, 0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0005524=ATP binding" "0007165=signal transduction, 0006468=protein phosphorylation, 0007417=central nervous system development, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway" "0016021=integral component of membrane, 0016020=membrane, 0005886=plasma membrane" "ROR1, ROR, DRor, Dror, HD-2, DmHD-2, CG4926" "IPR013806=Kringle-like fold, IPR018056=Kringle, conserved site, IPR020067=Frizzled domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR002011=Tyrosine-protein kinase, receptor class II, conserved site, IPR000719=Protein kinase domain, IPR000001=Kringle, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR017441=Protein kinase, ATP binding site" CG4926 16-Dec-15 2015_12 ENSDARG00000015176(si:dkey-209n16.1) WBGene00000289(cam-1) "ENSXETG00000000802(Ror2),ENSXETG00000010832(ROR1)" "ENSMUSG00000035305(Ror1),ENSMUSG00000021464(Ror2)" "ENSG00000185483(ROR1),ENSG00000169071(ROR2)" " embryonic stage | stage >=11 , embryonic stage " " central nervous system

, embryonic peripheral nervous system | restricted

" viable FBgn0263387 CG43439 http://flybase.net/reports/FBgn0263387.html protein_coding_gene CG43439 16-Dec-15 2015_12 FBgn0063494 GstE6 Glutathione S transferase E6 http://flybase.net/reports/FBgn0063494.html FBgn0034340 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "CT38747, E6, CG17530, GSTE6, glutathione transferase E6, gste6, gstE6, DmGSTE6" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG17530 16-Dec-15 2015_12 YLL060C(GTT2) DRSC06676 K -0.416586668 0.273022853 -0.119957201 0.504020855 -1.973981852 0.016004427 FBgn0039561 mfrn mitoferrin http://flybase.net/reports/FBgn0039561.html FBgn0025206 protein_coding_gene 0022857=transmembrane transporter activity "0055085=transmembrane transport, 0048515=spermatid differentiation, 0006839=mitochondrial transport" "0031966=mitochondrial membrane, 0005739=mitochondrion" "CG4963, dmfrn, anon-fast-evolving-2H5, Mfrn, HD35059, Mitoferrin, anon-EST:fe2H5, unnamed" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein" CG4963 16-Dec-15 2015_12 "ENSDARG00000052994(slc25a28),ENSDARG00000053914(LOC100331963)" "YJL133W(MRS3),YKR052C(MRS4)" WBGene00012204(W02B12.9) ENSXETG00000007767(SLC25A37) "ENSMUSG00000034248(Slc25a37),ENSMUSG00000040414(Slc25a28)" "ENSG00000147454(SLC25A37),ENSG00000155287(SLC25A28)" "male sterile,recessive,female fertile,partially lethal - majority die,some die during pupal stage,viable,fertile" "spermatozoon,elongation stage spermatid,mitochondrial derivative,spermatid cyst" FBgn0044395 Scim33 Sensitized chromosome inheritance modifier 33 http://flybase.net/reports/FBgn0044395.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0011158 l(1)Q236 lethal (1) Q236 http://flybase.net/reports/FBgn0011158.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0263902 M7.S http://flybase.net/reports/FBgn0263902.html gene 16-Dec-15 2015_12 "decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0065429 l(2)SH1499 lethal (2) SH1499 http://flybase.net/reports/FBgn0065429.html gene l(2)SH2 1499 16-Dec-15 2015_12 "lethal,recessive" FBgn0037292 CG2022 http://flybase.net/reports/FBgn0037292.html protein_coding_gene "0016021=integral component of membrane, 0005778=peroxisomal membrane" IPR007248=Mpv17/PMP22 CG2022 16-Dec-15 2015_12 YLR251W(SYM1) viable FBgn0011840 tRNA:A:90C transfer RNA:ala:90C http://flybase.net/reports/FBgn0011840.html "FBgn0051574, FBgn0060278" tRNA_gene "0033453=GCU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[[Ala]], tRNA:ala:90C, chr3R.trna56-AlaAGC, tRNA[Ala], CR31574, Ala, tRNA:A:AGC:AE002708-k, AE002708.trna50-AlaAGC" CR31574 16-Dec-15 2015_12 FBgn0058205 CG40205 http://flybase.net/reports/FBgn0058205.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005518 l(1)2Di lethal (1) 2Di http://flybase.net/reports/FBgn0005518.html gene "N6, l(1)N6" 16-Dec-15 2015_12 "lethal,recessive" FBgn0263997 CG43740 http://flybase.net/reports/FBgn0263997.html "FBgn0030192, FBgn0030193" protein_coding_gene 0046331=lateral inhibition 0005654=nucleoplasm "CG12641, CG15307" CG43740 16-Dec-15 2015_12 FBgn0050410 Rpi Ribose-5-phosphate isomerase http://flybase.net/reports/FBgn0050410.html FBgn0034848 protein_coding_gene 0004751=ribose-5-phosphate isomerase activity "0009052=pentose-phosphate shunt, non-oxidative branch, 0001315=age-dependent response to reactive oxygen species" "rpi, CG9872, ribose-5-phosphate isomerase, CG30410" "IPR004788=Ribose 5-phosphate isomerase, type A" CG30410 16-Dec-15 2015_12 ENSDARG00000056640(rpia) YOR095C(RKI1) WBGene00015101(rpia-1) ENSXETG00000005702(RPIA) ENSMUSG00000053604(Rpia) ENSG00000153574(RPIA) "oxidative stress response defective,long lived,viable" FBgn0040529 COX7A Cytochrome c oxidase subunit 7A http://flybase.net/reports/FBgn0040529.html protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" "0005739=mitochondrion, 0005751=mitochondrial respiratory chain complex IV" "COXJ, COXK, Cytochrome c oxidase Polypeptide VIIA, CG9603, Cytochrome c oxidase Polypeptide VIIa, Cytochrome c oxidase polypeptide VIIa, VIIa, Cytochrome c oxidase VIIa" "IPR003177=Cytochrome c oxidase, subunit VIIa" CG9603 16-Dec-15 2015_12 "ENSMUSG00000066553(Gm6969),ENSMUSG00000024248(Cox7a2l)" ENSG00000161281(COX7A1) "viable,visible" "trichogen cell,mesothoracic tergum" DRSC16514 EK -1.032480596 -1.245219586 -1.763575084 -0.562674272 0.372743884 1.882061775 FBgn0060593 l(3)S092415b lethal (3) S092415b http://flybase.net/reports/FBgn0060593.html gene 0924/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0000855 fs(1)M48 female sterile (1) M48 http://flybase.net/reports/FBgn0000855.html gene 16-Dec-15 2015_12 female sterile chorion FBgn0058339 CG40339 http://flybase.net/reports/FBgn0058339.html FBan0040339 protein_coding_gene 16-Dec-15 2015_12 DRSC20981 E -0.792467696 -0.513502664 1.385064589 1.565609211 FBgn0259594 B0583 http://flybase.net/reports/FBgn0259594.html gene 16-Dec-15 2015_12 lethal wing FBgn0085545 CG40958 http://flybase.net/reports/FBgn0085545.html FBan0040958 protein_coding_gene 16-Dec-15 2015_12 FBgn0024985 CG11448 http://flybase.net/reports/FBgn0024985.html protein_coding_gene 0048812=neuron projection morphogenesis EG:132E8.4 "IPR019143=JNK/Rab-associated protein-1, N-terminal" CG11448 16-Dec-15 2015_12 WBGene00007860(C32A3.3) ENSMUSG00000029392(Rilpl1) ENSG00000188026(RILPL1) "viable,fertile" FBgn0036202 CG6024 http://flybase.net/reports/FBgn0036202.html protein_coding_gene CT18912 "IPR000859=CUB domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG6024 16-Dec-15 2015_12 "viable,fertile" FBgn0038071 Dtg Dpp target gene http://flybase.net/reports/FBgn0038071.html protein_coding_gene 0007369=gastrulation "0009986=cell surface, 0031982=vesicle" CG6234 CG6234 16-Dec-15 2015_12 "lethal,visible" "embryonic head,germ band,crossvein,ectopic,wing" DRSC15998 K 0.312648607 0.23782767 0.366990237 0.293949921 0.976832397 1.670911511 FBgn0025792 Su(var)b301 Suppressor of variegation b301 http://flybase.net/reports/FBgn0025792.html gene Su-var(2)b301 16-Dec-15 2015_12 FBgn0051235 CG31235 http://flybase.net/reports/FBgn0051235.html "FBgn0038604, FBgn0038605" protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process "CG14311, CG7117" "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG31235 16-Dec-15 2015_12 YOR246C() viable FBgn0030174 CG15312 http://flybase.net/reports/FBgn0030174.html protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis CT35293 "IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2" CG15312 16-Dec-15 2015_12 viable FBgn0267764 CR46095 http://flybase.net/reports/FBgn0267764.html non_protein_coding_gene CR46095 16-Dec-15 2015_12 FBgn0033599 CG13223 http://flybase.net/reports/FBgn0033599.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane IPR004837=Sodium/calcium exchanger membrane region CG13223 16-Dec-15 2015_12 WBGene00003572(ncx-7) viable FBgn0033665 Zip48C Zinc/iron regulated transporter-related protein 48C http://flybase.net/reports/FBgn0033665.html protein_coding_gene 0046873=metal ion transmembrane transporter activity "0055085=transmembrane transport, 0030001=metal ion transport" 0016020=membrane "dZip48C, CG13189, cg13189" IPR003689=Zinc/iron permease CG13189 16-Dec-15 2015_12 WBGene00019077(F59A3.4) ENSXETG00000009976(slc39a11) ENSMUSG00000041654(Slc39a11) ENSG00000133195(SLC39A11) "viable,fertile" FBgn0050250 tRNA:CR30250 transfer RNA:CR30250 http://flybase.net/reports/FBgn0050250.html FBgn0060206 tRNA_gene 0033426=CAC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:H:GTG:AE002787-c, CR30250, tRNA[His], AE002787.trna20-HisGTG, chr2R.trna79-HisGTG" CR30250 16-Dec-15 2015_12 FBgn0265874 CR44663 http://flybase.net/reports/FBgn0265874.html non_protein_coding_gene lincRNA.999 CR44663 16-Dec-15 2015_12 FBgn0010107 daeh daeh http://flybase.net/reports/FBgn0010107.html gene 0008258=head involution 16-Dec-15 2015_12 "lethal,recessive" "embryonic head,cephalopharyngeal skeleton,embryonic epidermis,dorsal" FBgn0024655 l(2)k08136 lethal (2) k08136 http://flybase.net/reports/FBgn0024655.html gene 81/36 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0052246 CG32246 http://flybase.net/reports/FBgn0052246.html protein_coding_gene IPR019049=Nucleoporin protein Ndc1-Nup CG32246 16-Dec-15 2015_12 "viable,planar polarity defective" FBgn0044037 Mod(rst)B42 Mod(rst)B42 http://flybase.net/reports/FBgn0044037.html gene 0001745=compound eye morphogenesis B42 16-Dec-15 2015_12 viable eye FBgn0261835 CR42767 http://flybase.net/reports/FBgn0261835.html non_protein_coding_gene CR42767 16-Dec-15 2015_12 FBgn0085314 CR34285 http://flybase.net/reports/FBgn0085314.html pseudogene_attribute CR34285 16-Dec-15 2015_12 FBgn0264637 constricted constricted http://flybase.net/reports/FBgn0264637.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0024728 Slip1 Slip1 http://flybase.net/reports/FBgn0024728.html FBgn0039919 protein_coding_gene "0015459=potassium channel regulator activity, 0005515=protein binding" "dSLIP1, CG1783" IPR001478=PDZ domain CG1783 16-Dec-15 2015_12 "ENSDARG00000060182,ENSDARG00000045687(si:dkey-240a12.3),ENSDARG00000067598" "ENSXETG00000000401(PDZRN3),ENSXETG00000006793(PDZRN4),ENSXETG00000000725(PDZD4)" "ENSMUSG00000002006(Pdzd4),ENSMUSG00000035357(Pdzrn3),ENSMUSG00000036218" "ENSG00000067840(PDZD4),ENSG00000121440(PDZRN3),ENSG00000165966(PDZRN4)" viable FBgn0002825 ms(2)E4 male sterile (2) E4 http://flybase.net/reports/FBgn0002825.html gene "ms(2)2.4, ms2.4" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0039368 CG17196 http://flybase.net/reports/FBgn0039368.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005783=endoplasmic reticulum CG17196-PA "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17196 16-Dec-15 2015_12 YOL003C(PFA4) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) viable FBgn0011163 l(1)Q248 lethal (1) Q248 http://flybase.net/reports/FBgn0011163.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0015781 P5cr Pyrroline 5-carboyxlate reductase http://flybase.net/reports/FBgn0015781.html protein_coding_gene 0004735=pyrroline-5-carboxylate reductase activity "0006561=proline biosynthetic process, 0055114=oxidation-reduction process" "reductase, pyrroline 5-carboxylate, CG6009, P5CR" "IPR000304=Pyrroline-5-carboxylate reductase, IPR016040=NAD(P)-binding domain, IPR028939=Pyrroline-5-carboxylate reductase, catalytic, N-terminal, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR029036=Pyrroline-5-carboxylate reductase, dimerisation domain" CG6009 16-Dec-15 2015_12 YER023W(PRO3) viable FBgn0036320 CG10943 http://flybase.net/reports/FBgn0036320.html protein_coding_gene CG10943 16-Dec-15 2015_12 FBgn0010792 l(3)03076 lethal (3) 03076 http://flybase.net/reports/FBgn0010792.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267599 CR45937 http://flybase.net/reports/FBgn0267599.html non_protein_coding_gene lincRNA.600 CR45937 16-Dec-15 2015_12 FBgn0039370 CG4956 http://flybase.net/reports/FBgn0039370.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG4956 16-Dec-15 2015_12 ENSDARG00000036364(zdhhc24) YOL003C(PFA4) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) viable FBgn0060885 l(3)S044738 lethal (3) S044738 http://flybase.net/reports/FBgn0060885.html gene 0447/38 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065187 l(2)SH2345 lethal (2) SH2345 http://flybase.net/reports/FBgn0065187.html gene l(2)SH2 2345 16-Dec-15 2015_12 "lethal,recessive" FBgn0267827 CR46148 http://flybase.net/reports/FBgn0267827.html non_protein_coding_gene CR46148 16-Dec-15 2015_12 FBgn0038312 Zip88E Zinc/iron regulated transporter-related protein 88E http://flybase.net/reports/FBgn0038312.html protein_coding_gene 0046873=metal ion transmembrane transporter activity "0055085=transmembrane transport, 0030001=metal ion transport" "0016323=basolateral plasma membrane, 0005622=intracellular" "CG4334, cg4334, dZip88E" IPR003689=Zinc/iron permease CG4334 16-Dec-15 2015_12 "YLR130C(ZRT2),YGL255W(ZRT1)" "viable,fertile" FBgn0015852 anon-10Ce anon-10Ce http://flybase.net/reports/FBgn0015852.html gene 16-Dec-15 2015_12 FBgn0083055 snoRNA:ë¬18S-1295 snoRNA:ë¬18S-1295 http://flybase.net/reports/FBgn0083055.html snoRNA_gene "CR34615, Psi 18S-1295, psi18s-1295, chr3R:16648312..16648503" CR34615 16-Dec-15 2015_12 FBgn0263903 l(3)OL24 http://flybase.net/reports/FBgn0263903.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0066077 Stalker4\ORF1 ORF1 http://flybase.net/reports/FBgn0066077.html transposable_element_gene ORF1 16-Dec-15 2015_12 FBgn0030151 CG1354 http://flybase.net/reports/FBgn0030151.html protein_coding_gene 0005525=GTP binding "IPR004396=Ribosome-binding ATPase YchF/Obg-like ATPase 1, IPR012675=Beta-grasp domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR031167=OBG-type guanine nucleotide-binding (G) domain, IPR006073=GTP binding domain, IPR023192=TGS-like domain, IPR012676=TGS-like, IPR013029=Domain of unknown function DUF933" CG1354 16-Dec-15 2015_12 ENSDARG00000044565(ola1) YBR025C(OLA1) WBGene00012344(tag-210) ENSXETG00000008500(TTpA007h13.1) ENSMUSG00000027108(Ola1) ENSG00000138430(OLA1) viable FBgn0024371 E2f2 E2F transcription factor 2 http://flybase.net/reports/FBgn0024371.html protein_coding_gene "0001012=RNA polymerase II regulatory region DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0008134=transcription factor binding" "0007310=oocyte dorsal/ventral axis specification, 0007314=oocyte anterior/posterior axis specification, 0008156=negative regulation of DNA replication, 0007113=endomitotic cell cycle, 0042023=DNA endoreduplication, 0007444=imaginal disc development, 0048477=oogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0000082=G1/S transition of mitotic cell cycle" "0031523=Myb complex, 0035189=Rb-E2F complex, 0000785=chromatin" "E2F2, E2F, dE2F-2, CG1071, e2f2, dE2F2, dE2f2, de2f2, E2f" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR003316=E2F/DP family, winged-helix DNA-binding domain, IPR015633=E2F Family" CG1071 16-Dec-15 2015_12 embryonic stage -- adult stage "female sterile,partially,viable,fertile,wild-type,male fertile,recessive,reduced,partially lethal - majority live,visible" "chorion,follicle cell & nucleus, with Df(2L)DS8, E2f21-188,follicle cell & nucleusDS8), with E2f21-188,follicle cell & nucleus, with E2f2329/Df(2L)DS8,follicle cell & nucleus, with Df(2L)DS8, E2f2329,follicle cell & nucleus, with Df(2L)DS8, E2f2k16402a,follicle cell & nucleus, with E2f2k16402a/Df(2L)DS8,follicle cell,follicle cell & nucleus,salivary gland & nucleus,eye,ommatidium" FBgn0002520 l(3)XaR lethal (3) XaR http://flybase.net/reports/FBgn0002520.html gene 16-Dec-15 2015_12 lethal FBgn0019734 l(1)A10 lethal (1) A10 http://flybase.net/reports/FBgn0019734.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266747 CR45220 http://flybase.net/reports/FBgn0266747.html non_protein_coding_gene CR45220 16-Dec-15 2015_12 FBgn0015915 bk64 bk64 http://flybase.net/reports/FBgn0015915.html gene 16-Dec-15 2015_12 FBgn0267930 CR46211 http://flybase.net/reports/FBgn0267930.html non_protein_coding_gene lincRNA.1008 CR46211 16-Dec-15 2015_12 FBgn0036349 SNCF SoxNeuro Co-Factor http://flybase.net/reports/FBgn0036349.html FBgn0047094 protein_coding_gene 0005515=protein binding "0032879=regulation of localization, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005730=nucleolus" "BcDNA:RE54375, HL6, CG14112, SCNF" IPR007970=Protein of unknown function DUF733 CG14112 16-Dec-15 2015_12 viable FBgn0001860 l(1)VA335 lethal (1) VA335 http://flybase.net/reports/FBgn0001860.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0021899 l(2)k12701 lethal (2) k12701 http://flybase.net/reports/FBgn0021899.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0052221 CG32221 http://flybase.net/reports/FBgn0052221.html FBgn0062129 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "FBXL18, anon-WO0118547.270" CG32221 16-Dec-15 2015_12 viable FBgn0041195 Pkd2 Polycystic kidney disease 2 ortholog (H. sapiens) http://flybase.net/reports/FBgn0041195.html FBgn0032425 protein_coding_gene 0005261=cation channel activity "0030317=sperm motility, 0046693=sperm storage, 0007283=spermatogenesis, 0006812=cation transport, 0030536=larval feeding behavior, 0046692=sperm competition, 0006939=smooth muscle contraction" 0034703=cation channel complex "Polycystic kidney disease gene-2, PKD2, Amo, TRPP, AMO, Almost there, amo, polycystin-2, almost there, pkd2, CG6504, Dmpkd2" "IPR013122=Polycystin cation channel, PKD1/PKD2" CG6504 16-Dec-15 2015_12 "ENSDARG00000014098(pkd2),ENSDARG00000022503(pkd2l1)" WBGene00004035(pkd-2) "ENSMUSG00000037578(Pkd2l1),ENSMUSG00000034462(Pkd2),ENSMUSG00000014503(Pkd2l2)" "ENSG00000107593(PKD2L1),ENSG00000118762(PKD2),ENSG00000078795(PKD2L2)" "male semi-sterile,feeding behavior defective,male sterile,partially,viable" "spermatozoon,flagellum (obsolete )" FBgn0000560 eg eagle http://flybase.net/reports/FBgn0000560.html FBgn0000563 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003707=steroid hormone receptor activity, 0008270=zinc ion binding, 0043565=sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity" "0007417=central nervous system development, 0006355=regulation of transcription, DNA-templated, 0043401=steroid hormone mediated signaling pathway" 0005634=nucleus "Egl, egon, Eagle, NR0A3, embryonic gonad, Embryonic gonad, Eg, Egon, eagle, egl, EGON, T1 transcription unit, spready, eag, T1, CG7383, spy" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR013088=Zinc finger, NHR/GATA-type" CG7383 16-Dec-15 2015_12 " embryonic stage | stage 11-12 , embryonic stage | stage 14 " " neuroblast NB3-3

, neuroblast NB7-3

, neuroblast NB6-4

, neuroblast NB2-4

, dorsal fold

, embryonic central nervous system | presumptive | restricted

, neuroblast of ventral nerve cord primordium | subset

" "viable,visible,recessive,dominant,flightless,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,fertile" "wing,serotonergic neuron,EW1 neuron,serotonin neuron & ventral nerve cord,ventral nerve cord & serotonin neuron,neuroblast NB7-3,wing sensillum,ectopic,embryonic dorsal epidermis,dorsal closure embryo,embryonic/larval hemocyte | third instar larval stage" FBgn0032788 CG13084 http://flybase.net/reports/FBgn0032788.html protein_coding_gene 0042600=chorion CG13084 16-Dec-15 2015_12 viable FBgn0043898 gsb::Poxn gsb::Poxn http://flybase.net/reports/FBgn0043898.html engineered_fusion_gene gsb::Pox-n 16-Dec-15 2015_12 "lethal,visible" "eye,adult head,antenna" FBgn0010596 l(2)05337 lethal (2) 05337 http://flybase.net/reports/FBgn0010596.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0264559 shf::Drer\wif1 http://flybase.net/reports/FBgn0264559.html engineered_fusion_gene 16-Dec-15 2015_12 partially lethal - majority die "wing,wing margin bristle" FBgn0034200 CG11395 http://flybase.net/reports/FBgn0034200.html protein_coding_gene 0005125=cytokine activity 0007165=signal transduction 0005576=extracellular region CG11395 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266058 Su(var)203 http://flybase.net/reports/FBgn0266058.html gene 203 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0032590 CG4631 http://flybase.net/reports/FBgn0032590.html protein_coding_gene CG4631 16-Dec-15 2015_12 viable FBgn0267497 28SrRNA:CR45837 28S ribosomal RNA:CR45837 http://flybase.net/reports/FBgn0267497.html rRNA_gene CR45837 CR45837 16-Dec-15 2015_12 FBgn0001254 ImpE2 Ecdysone-inducible gene E2 http://flybase.net/reports/FBgn0001254.html protein_coding_gene 0007561=imaginal disc eversion "0019898=extrinsic component of membrane, 0005737=cytoplasm, 0005576=extracellular region" "Imp-E2, IMP-E2, CG1934" CG1934 16-Dec-15 2015_12 " prepupal stage | 0-4 hr , embryonic stage | 12-15 hr , embryonic stage--pupal stage " " embryonic/larval proventriculus

, ectoderm

" embryonic stage | 12-15 hr ectoderm

viable FBgn0030258 CG1552 http://flybase.net/reports/FBgn0030258.html FBgn0027721 protein_coding_gene 0005615=extracellular space anon-EST:Posey230 CG1552 16-Dec-15 2015_12 "viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0040364 CG11378 http://flybase.net/reports/FBgn0040364.html FBgn0029561 protein_coding_gene EG:BACR42I17.2 IPR009832=Protein of unknown function DUF1397 CG11378 16-Dec-15 2015_12 "viable,fertile" FBgn0262874 CG43229 http://flybase.net/reports/FBgn0262874.html protein_coding_gene "chrX_18032634_18033088.0, lincRNA.1011" CG43229 16-Dec-15 2015_12 FBgn0039696 CG7837 http://flybase.net/reports/FBgn0039696.html protein_coding_gene 0005829=cytosol "IPR011989=Armadillo-like helical, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR016024=Armadillo-type fold" CG7837 16-Dec-15 2015_12 ENSXETG00000018792(ARMC5) ENSMUSG00000042178(Armc5) "viable,fertile" FBgn0084305 foil foiled coil http://flybase.net/reports/FBgn0084305.html gene 0008584=male gonad development 16-Dec-15 2015_12 FBgn0030245 CG1637 http://flybase.net/reports/FBgn0030245.html protein_coding_gene "0003993=acid phosphatase activity, 0046872=metal ion binding" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like, IPR008963=Purple acid phosphatase-like, N-terminal, IPR025733=Iron/zinc purple acid phosphatase-like C-terminal domain, IPR015914=Purple acid phosphatase, N-terminal" CG1637 16-Dec-15 2015_12 ENSDARG00000063667(zgc:162913) WBGene00008992(F21A3.2) ENSMUSG00000037469(C330005M16Rik) ENSG00000183760(PAPL) FBgn0002587 M(1)11F Minute (1) 11F http://flybase.net/reports/FBgn0002587.html gene 16-Dec-15 2015_12 FBgn0038597 CG8064 http://flybase.net/reports/FBgn0038597.html protein_coding_gene "0009267=cellular response to starvation, 0022008=neurogenesis" "IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR007148=Small-subunit processome, Utp12" CG8064 16-Dec-15 2015_12 ENSDARG00000011079(wdr3) YLR129W(DIP2) WBGene00017435(F13H8.2) ENSXETG00000009920(wdr3) ENSMUSG00000033285(Wdr3) ENSG00000065183(WDR3) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0005067 fs(2)OW208 female sterile (2) OW208 http://flybase.net/reports/FBgn0005067.html gene 16-Dec-15 2015_12 FBgn0031544 CG17593 http://flybase.net/reports/FBgn0031544.html protein_coding_gene "0012505=endomembrane system, 0005737=cytoplasm" IPR012879=Protein of unknown function DUF1682 CG17593 16-Dec-15 2015_12 ENSDARG00000054362(LOC100334909) WBGene00014204(ccdc-47) ENSXETG00000003246(CCDC47) ENSMUSG00000078622(Ccdc47) ENSG00000108588(CCDC47) viable DRSC27490 K -0.138381969 0.353751013 0.132296996 0.622310441 2.479600671 2.567925918 FBgn0038743 CG11667 http://flybase.net/reports/FBgn0038743.html protein_coding_gene 0004085=butyryl-CoA dehydrogenase activity 16-Dec-15 2015_12 FBgn0043851 wwg wrinkled wing http://flybase.net/reports/FBgn0043851.html gene 16-Dec-15 2015_12 FBgn0265940 CR44727 http://flybase.net/reports/FBgn0265940.html non_protein_coding_gene CR44727 16-Dec-15 2015_12 FBgn0051416 tRNA:CR31416 transfer RNA:CR31416 http://flybase.net/reports/FBgn0051416.html FBgn0060255 tRNA_gene 0033458=GAC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31416, tRNA[Asp-GTC], tRNA:D:GTC:AE002708-c, chr3R.trna42-AspGTC, tRNA[[Asp]], AE002708.trna36-AspGTC" CR31416 16-Dec-15 2015_12 FBgn0015902 Ori93Fë± Ori93Fë± http://flybase.net/reports/FBgn0015902.html origin_of_replication oriDalpha 16-Dec-15 2015_12 FBgn0264954 fd3F forkhead domain 3F http://flybase.net/reports/FBgn0264954.html "FBgn0061173, FBgn0029678, FBgn0052779, FBgn0029677, FBgn0042113" protein_coding_gene "0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000976=transcription regulatory region sequence-specific DNA binding, 0008301=DNA binding, bending, 0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0048806=genitalia development, 0007389=pattern specification process, 0048813=dendrite morphogenesis, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0009888=tissue development, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005667=transcription factor complex" "CG12632, Forkhead domain 3F, fd3f, CG32779, CG44123, CG18771, Fd3F, CG15238" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain" CG44123 16-Dec-15 2015_12 DRSC18160 K -0.012682742 -0.164782918 -0.15475681 0.239220993 2.289795239 -0.325215613 FBgn0027138 l(3)87Di lethal (3) 87Di http://flybase.net/reports/FBgn0027138.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0264522 ff28 http://flybase.net/reports/FBgn0264522.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" FBgn0250831 BG642167 http://flybase.net/reports/FBgn0250831.html "FBgn0083939, FBgn0066987" protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "BG642167, BG642167(1a8), CG34103, anon-SAGE:Wang-011, 1a8" CG34103 16-Dec-15 2015_12 viable FBgn0026373 RpII33 RNA polymerase II 33kD subunit http://flybase.net/reports/FBgn0026373.html FBgn0001964 protein_coding_gene "0046983=protein dimerization activity, 0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0006366=transcription from RNA polymerase II promoter, 0034605=cellular response to heat" "0005634=nucleus, 0005737=cytoplasm, 0005665=DNA-directed RNA polymerase II, core complex, 0005703=polytene chromosome puff, 0005875=microtubule associated complex" "l34Dg, D-rpII33, Rpb3, RNAP, 152117_at, Pol II RPII33, BG:DS00941.10, lethal(2)34Dg, rpb3, l(2)br17, PolIIo, Pol II, RPB3, RNA pol II, l(2)k05605, lethal 17 in the black-reduced region, RNA Pol II, Rbp3, pol II, RNA Polymerase II, polII, l(2)34Dg, br17, rpII33, RNA polII, Rpll33, PolII, RNA polymerase II, CG7885" "IPR009025=DNA-directed RNA polymerase, RBP11-like dimerisation domain, IPR011262=DNA-directed RNA polymerase, insert domain, IPR011263=DNA-directed RNA polymerase, RpoA/D/Rpb3-type, IPR001514=DNA-directed RNA polymerase, 30-40kDa subunit, conserved site" CG7885 16-Dec-15 2015_12 ENSDARG00000033596(polr2c) YIL021W(RPB3) WBGene00007971(rpb-3) ENSXETG00000013784(POLR2C) ENSMUSG00000031783(Polr2c) ENSG00000102978(POLR2C) "lethal,recessive" DRSC03415 IEK -1.394521917 2.807449998 1.804797464 -1.954444356 1.623100273 3.925555937 FBgn0266742 CR45215 http://flybase.net/reports/FBgn0266742.html non_protein_coding_gene CR45215 16-Dec-15 2015_12 FBgn0025777 homer homer http://flybase.net/reports/FBgn0025777.html FBgn0026588 protein_coding_gene 0005515=protein binding "0045938=positive regulation of circadian sleep/wake cycle, sleep, 0048149=behavioral response to ethanol, 0030534=adult behavior, 0040012=regulation of locomotion, 0045471=response to ethanol" "0005783=endoplasmic reticulum, 0030425=dendrite" "Drosophila Ves-1 homolog, Dhom, BEST:LD03829, LD03829, Homer, Dvh, d-Homer, Dm Homer, CG11324, Dhomer, dhom, Hom" "IPR000697=WH1/EVH1 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG11324 16-Dec-15 2015_12 "ENSDARG00000007517(LOC100333527),ENSDARG00000018108(homer1),ENSDARG00000010789(zgc:55557)" "ENSXETG00000000519(HOMER1),ENSXETG00000010136(HOMER3),ENSXETG00000016094(homer2)" "ENSMUSG00000025813(Homer2),ENSMUSG00000007617(Homer1),ENSMUSG00000003573(Homer3)" "ENSG00000103942(HOMER2),ENSG00000152413(HOMER1),ENSG00000051128(HOMER3)" "viable,partially lethal - majority die,visible,lethal,fertile,courtship behavior defective,male,recessive,hyperactive,smell perception defective,stress response defective,chemical sensitive,sleep defective" tarsal segment FBgn0027492 wdb widerborst http://flybase.net/reports/FBgn0027492.html "FBgn0026590, FBgn0043349" protein_coding_gene 0008601=protein phosphatase type 2A regulator activity "0007165=signal transduction, 0051225=spindle assembly, 0006914=autophagy, 0007059=chromosome segregation, 0051726=regulation of cell cycle, 0008340=determination of adult lifespan" 0000159=protein phosphatase type 2A complex "PP2a, Widerborst, LD02456, dPP2A-B56-2, Wiederborst, PP2A[B'-2], dPP2A, PP2A regulatory subunit, protein phosphatase PP2A, dB56-2, B56-2, CG5643, WDB, BcDNA:LD34343, Wdb, l(3)S031807, PP2A, EP3559, PP2A B subunit, BEST:LD02456, PP2-AB, protein phosphatase 2a, 0318/07" "IPR002554=Protein phosphatase 2A, regulatory B subunit, B56, IPR016024=Armadillo-type fold" CG5643 16-Dec-15 2015_12 "ENSDARG00000069118(ppp2r5eb),ENSDARG00000015474(ppp2r5ea),ENSDARG00000027017(ppp2r5a)" WBGene00012348(pptr-1) "ENSXETG00000003584(Ppp2r5e),ENSXETG00000014382(Ppp2r5a)" "ENSMUSG00000021051(Ppp2r5e),ENSMUSG00000026626(Ppp2r5a)" "ENSG00000154001(PPP2R5E),ENSG00000066027(PPP2R5A)" "visible,long lived,heat sensitive,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,neuroanatomy defective,locomotor rhythm defective,planar polarity defective,somatic clone,increased cell death,partially lethal - majority die,wild-type,viable" "eye,wing,wing hair,supernumerary,anterior fascicle & synapse,intersegmental nerve,trichogen cell,ectopic,tormogen cell,somatic clone,eye disc,tarsal segment" FBgn0028935 CG7653 http://flybase.net/reports/FBgn0028935.html protein_coding_gene "0008270=zinc ion binding, 0004177=aminopeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis 0005886=plasma membrane BG:DS00365.1 "IPR024571=ERAP1-like C-terminal domain, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG7653 16-Dec-15 2015_12 viable FBgn0000764 fs(1)A572 female sterile (1) A572 http://flybase.net/reports/FBgn0000764.html gene fs(1)572 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,recessive,female sterile" "embryo,blastoderm embryo" FBgn0016948 tilE touch insensitive larva E http://flybase.net/reports/FBgn0016948.html gene line 375 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0000278 CecB Cecropin B http://flybase.net/reports/FBgn0000278.html protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0006959=humoral immune response, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0050832=defense response to fungus, 0050830=defense response to Gram-positive bacterium, 0019731=antibacterial humoral response, 0042742=defense response to bacterium" "0005615=extracellular space, 0005576=extracellular region" "unnamed, Cec, CG1878, cecB, cecropin B, crpB, Cecropin-B, cecropin, cercropin B, Cecropin-B precursor, Cec B, cedcB, Cecropin, cec" "IPR000875=Cecropin, IPR020400=Cecropin, diptera" CG1878 16-Dec-15 2015_12 larval stage embryonic/larval hemocyte

viable FBgn0060990 l(3)S027604b lethal (3) S027604b http://flybase.net/reports/FBgn0060990.html gene 0276/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0027295 l(1)G0147 lethal (1) G0147 http://flybase.net/reports/FBgn0027295.html gene 16-Dec-15 2015_12 FBgn0037635 CG9837 http://flybase.net/reports/FBgn0037635.html "FBtr0081933, FBpp0081415" protein_coding_gene CG9837 16-Dec-15 2015_12 viable FBgn0085827 CR41621 http://flybase.net/reports/FBgn0085827.html FBan0041621 rRNA_gene CR41621 16-Dec-15 2015_12 FBgn0086422 l(3)CHf lethal (3) CHf http://flybase.net/reports/FBgn0086422.html gene complementation group 8 16-Dec-15 2015_12 "lethal,recessive" FBgn0014231 l(2)31En lethal (2) 31En http://flybase.net/reports/FBgn0014231.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069916 CG41136 http://flybase.net/reports/FBgn0069916.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267211 CR45651 http://flybase.net/reports/FBgn0267211.html non_protein_coding_gene CR45651 16-Dec-15 2015_12 FBgn0031640 Mon1 Mon1 ortholog http://flybase.net/reports/FBgn0031640.html protein_coding_gene 0005085=guanyl-nucleotide exchange factor activity 0032510=endosome to lysosome transport via multivesicular body sorting pathway "0005829=cytosol, 0035658=Mon1-Ccz1 complex" "MON1, CG11926, NP_608868" IPR004353=Vacuolar fusion protein MON1 CG11926 16-Dec-15 2015_12 "ENSDARG00000014870,ENSDARG00000035686(LOC100149301)" YGL124C(MON1) WBGene00018321(sand-1) ENSXETG00000007305(MON1A) "ENSMUSG00000032583(Mon1a),ENSMUSG00000078908(Mon1b)" "ENSG00000164077(MON1A),ENSG00000103111(MON1B)" "partially lethal,recessive,viable" "endosome | somatic clone,multivesicular bodyhh-Gal4" FBgn0060865 l(3)S047322b lethal (3) S047322b http://flybase.net/reports/FBgn0060865.html gene 0473/22 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0050500 CG30500 http://flybase.net/reports/FBgn0050500.html protein_coding_gene 16-Dec-15 2015_12 FBgn0277430 l(3)psg18 http://flybase.net/reports/FBgn0277430.html gene psg18 16-Dec-15 2015_12 FBgn0061069 l(3)S018717b lethal (3) S018717b http://flybase.net/reports/FBgn0061069.html gene 0187/17 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024713 anon-57Cn anon-57Cn http://flybase.net/reports/FBgn0024713.html gene unnamed 16-Dec-15 2015_12 FBgn0086399 BG02386 http://flybase.net/reports/FBgn0086399.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0025573 PpN58A Protein phosphatase N at 58A http://flybase.net/reports/FBgn0025573.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0016787=hydrolase activity" 0006470=protein dephosphorylation 0005634=nucleus "DmPpN-58A, PpN-58A, CG3245, PPN 58A, PPN" "IPR029052=Metallo-dependent phosphatase-like, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG3245 16-Dec-15 2015_12 viable FBgn0040593 CG13824 http://flybase.net/reports/FBgn0040593.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035266 Gk Glycerol kinase http://flybase.net/reports/FBgn0035266.html protein_coding_gene 0004370=glycerol kinase activity "0005975=carbohydrate metabolic process, 0046167=glycerol-3-phosphate biosynthetic process" "dGK, CG7995, glycerol kinase" "IPR018485=Carbohydrate kinase, FGGY, C-terminal, IPR000577=Carbohydrate kinase, FGGY, IPR005999=Glycerol kinase, IPR018484=Carbohydrate kinase, FGGY, N-terminal, IPR018483=Carbohydrate kinase, FGGY, conserved site" CG7995 16-Dec-15 2015_12 YHL032C(GUT1) WBGene00020007(R11F4.1) "chemical sensitive,viable" FBgn0062961 pncr016:2R putative noncoding RNA 016:2R http://flybase.net/reports/FBgn0062961.html FBgn0053942 non_protein_coding_gene "CR33942, BcDNA:RH09485, pncr016" CR33942 16-Dec-15 2015_12 FBgn0264083 CR43752 http://flybase.net/reports/FBgn0264083.html non_protein_coding_gene CR43752 16-Dec-15 2015_12 FBgn0023215 Mnt Mnt http://flybase.net/reports/FBgn0023215.html "FBgn0024333, FBgn0029674" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0046982=protein heterodimerization activity, 0005515=protein binding" "0030308=negative regulation of cell growth, 0006909=phagocytosis, 0048812=neuron projection morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0051726=regulation of cell cycle" "0005654=nucleoplasm, 0005634=nucleus" "Mad-3E, bHLHe43, CG13316, mnt, EG:114E2.2, dMad, Mad, dmnt, dMnt, MNT, CG2856, DmMnt" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG13316 16-Dec-15 2015_12 WBGene00003511(mxl-3) "viable,fertile,increased cell size,large body,short lived,visible,lethal,recessive,decreased cell size,somatic clone,starvation stress response defective" "wing hair,ommatidium,wing disc,somatic clone,wing,posterior compartment,adult head,eye,embryonic/larval fat body,mesothoracic tergum" FBgn0051957 CG31957 http://flybase.net/reports/FBgn0051957.html protein_coding_gene 0003743=translation initiation factor activity 0006413=translational initiation "IPR012340=Nucleic acid-binding, OB-fold, IPR006196=RNA-binding domain, S1, IF1 type" CG31957 16-Dec-15 2015_12 ENSDARG00000016280(zgc:63631) WBGene00014112(ZK856.11) ENSXETG00000011431(EIF1AD) ENSMUSG00000024841(Eif1ad) ENSG00000175376(EIF1AD) viable FBgn0036690 Ilp8 Insulin-like peptide 8 http://flybase.net/reports/FBgn0036690.html protein_coding_gene 0005158=insulin receptor binding "0071480=cellular response to gamma radiation, 0048638=regulation of developmental growth, 0008286=insulin receptor signaling pathway, 0009855=determination of bilateral symmetry, 0007304=chorion-containing eggshell formation, 0035073=pupariation" "0005615=extracellular space, 0042600=chorion" "CG14059, Drosophila insulin-like peptide 8, DILP8, dILP8, dilp8, dlip8" CG14059 16-Dec-15 2015_12 "developmental rate defective,size defective,viable,large body" "wing,imaginal disc" FBgn0010726 l(3)00716 lethal (3) 00716 http://flybase.net/reports/FBgn0010726.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0014961 fs(3)G1 female sterile (3) of Gill http://flybase.net/reports/FBgn0014961.html gene fs(3)1 16-Dec-15 2015_12 "female sterile,male fertile,meiotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "syncytial blastoderm embryo,spindle" FBgn0010181 tu(2)91k tu(2)91k http://flybase.net/reports/FBgn0010181.html gene "tu91k, tu-91k" 16-Dec-15 2015_12 "melanotic mass phenotype,visible,semidominant,female fertile,reduced" "melanotic mass,female" FBgn0070046 3L-61-3 3L-61-3 http://flybase.net/reports/FBgn0070046.html gene 0007379=segment specification 16-Dec-15 2015_12 "embryonic abdominal segment,germline clone,maternal effect" FBgn0013479 l(1)1P3 lethal (1) 1P3 http://flybase.net/reports/FBgn0013479.html gene 16-Dec-15 2015_12 "lethal,germline clone,maternal effect,recessive,neurogenic phenotype" FBgn0261542 ms(2)35Dj male sterile (2) 35Dj http://flybase.net/reports/FBgn0261542.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile FBgn0267125 CR45565 http://flybase.net/reports/FBgn0267125.html non_protein_coding_gene CR45565 16-Dec-15 2015_12 FBgn0058216 CG40216 http://flybase.net/reports/FBgn0058216.html protein_coding_gene 16-Dec-15 2015_12 FBgn0070053 2L-311-30 2L-311-30 http://flybase.net/reports/FBgn0070053.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,germline clone,maternal effect" FBgn0027939 sva53 sva53 http://flybase.net/reports/FBgn0027939.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive,germline clone" FBgn0264620 fz2::otk http://flybase.net/reports/FBgn0264620.html engineered_fusion_gene 16-Dec-15 2015_12 "denticle,ectopic,embryonic/first instar larval cuticle" FBgn0263581 CR43606 http://flybase.net/reports/FBgn0263581.html non_protein_coding_gene CR43606 16-Dec-15 2015_12 FBgn0039048 CG17111 http://flybase.net/reports/FBgn0039048.html protein_coding_gene 0000902=cell morphogenesis 0016021=integral component of membrane "IPR003609=PAN/Apple domain, IPR001507=Zona pellucida domain" CG17111 16-Dec-15 2015_12 viable FBgn0010682 l(2)s1976 lethal (2) s1976 http://flybase.net/reports/FBgn0010682.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011615 l(1)I33f3-1 lethal (1) I33f3-1 http://flybase.net/reports/FBgn0011615.html FBgn0010206 gene l(1)33f3 16-Dec-15 2015_12 lethal FBgn0022374 Pt-16 Larval protein-16 http://flybase.net/reports/FBgn0022374.html gene 16-Dec-15 2015_12 FBgn0259126 agu aguesic http://flybase.net/reports/FBgn0259126.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014290 l(3)64Ba lethal (3) 64Ba http://flybase.net/reports/FBgn0014290.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015885 anon-64Bg anon-64Bg http://flybase.net/reports/FBgn0015885.html gene 16-Dec-15 2015_12 adult stage adult head

FBgn0262893 CG43248 http://flybase.net/reports/FBgn0262893.html protein_coding_gene CG43248 16-Dec-15 2015_12 FBgn0023151 Su(mg)3-1 Suppressor of modifier of gypsy 3-1 http://flybase.net/reports/FBgn0023151.html gene 16-Dec-15 2015_12 FBgn0002706 mei-1 meiotic 1 http://flybase.net/reports/FBgn0002706.html gene meiotic mutant 1 16-Dec-15 2015_12 FBgn0030891 Ada3 transcriptional Adaptor 3 http://flybase.net/reports/FBgn0030891.html FBgn0026603 protein_coding_gene "0004402=histone acetyltransferase activity, 0003682=chromatin binding" "0043970=histone H3-K9 acetylation, 0044154=histone H3-K14 acetylation, 0043983=histone H4-K12 acetylation, 0043966=histone H3 acetylation, 0048096=chromatin-mediated maintenance of transcription, 0016573=histone acetylation, 0043967=histone H4 acetylation, 0043987=histone H3-S10 phosphorylation, 0006338=chromatin remodeling, 0035066=positive regulation of histone acetylation" "0005634=nucleus, 0000123=histone acetyltransferase complex, 0005703=polytene chromosome puff, 0005705=polytene chromosome interband, 0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0000124=SAGA complex, 0005700=polytene chromosome" "CG7098, dik, Ada3, DADA3, diskette, ADA3, dADA3, dAda3, HL-XIV" IPR019340=Histone acetyltransferases subunit 3 CG7098 16-Dec-15 2015_12 ENSDARG00000058220(tada3l) ENSXETG00000023674(Q66JG5_XENTR) ENSMUSG00000048930(Tada3) ENSG00000171148(TADA3) "size defective,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,non-enhancer of variegation,lethal,viable" "wing disc,germline cell,germline clone" DRSC20321 IK -0.015860604 1.510708513 -0.205271988 0.6411675 0.140543279 1.627589202 FBgn0023410 Ars-region44 Autonomous replicating sequence region 44 http://flybase.net/reports/FBgn0023410.html region "dARS44, Ars44" 16-Dec-15 2015_12 FBgn0060931 l(3)S041832 lethal (3) S041832 http://flybase.net/reports/FBgn0060931.html gene 0418/32 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033578 BBS4 Bardet-Biedl syndrome 4 ortholog (H. sapiens) http://flybase.net/reports/FBgn0033578.html protein_coding_gene "0003777=microtubule motor activity, 0034452=dynactin binding" "0042384=cilium assembly, 0051297=centrosome organization" "0000242=pericentriolar material, 0005929=cilium, 0034464=BBSome" "CG13232, BBS4" "IPR019734=Tetratricopeptide repeat, IPR013105=Tetratricopeptide repeat 2, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG13232 16-Dec-15 2015_12 ENSDARG00000063522(bbs4) WBGene00043992(F58A4.14) ENSXETG00000005200(bbs4) ENSMUSG00000025235(Bbs4) ENSG00000140463(BBS4) viable FBgn0265802 CR44591 http://flybase.net/reports/FBgn0265802.html non_protein_coding_gene CR44591 16-Dec-15 2015_12 FBgn0261174 ey::toy http://flybase.net/reports/FBgn0261174.html engineered_fusion_gene chimeric Ey/Toy 16-Dec-15 2015_12 "eye,ectopic,leg,antenna" FBgn0043858 pf-8 pairing failure-8 http://flybase.net/reports/FBgn0043858.html gene 0007140=male meiosis "CG8, Complementation group 8" 16-Dec-15 2015_12 FBgn0002694 md melanotic lesions http://flybase.net/reports/FBgn0002694.html gene 16-Dec-15 2015_12 visible "head,thorax,abdomen" FBgn0014389 e(Pc)84DE e(Pc)84DE http://flybase.net/reports/FBgn0014389.html gene "su(Pc)84DE, E(Pc)84DE" 16-Dec-15 2015_12 FBgn0019869 EP115 EP115 http://flybase.net/reports/FBgn0019869.html gene "unnamed, anon-98Fa" 16-Dec-15 2015_12 "visible,lethal,partially lethal - majority die" eye FBgn0261968 huc2L-20 hydroxyurea- and (or) caffeine-sensitive 2L-20 http://flybase.net/reports/FBgn0261968.html gene huc[2L-20] 16-Dec-15 2015_12 "chemical sensitive,somatic clone,lethal" "eye,somatic clone,drug conditional" FBgn0036589 CG13067 http://flybase.net/reports/FBgn0036589.html "FBgn0045907, FBgn0045915" protein_coding_gene "anon-WO0153538.46, anon-WO0153538.39" CG13067 16-Dec-15 2015_12 viable FBgn0036606 CG13060 http://flybase.net/reports/FBgn0036606.html FBgn0047108 protein_coding_gene BcDNA:RE40431 IPR007614=Retinin-like protein CG13060 16-Dec-15 2015_12 FBgn0250821 CG14644 http://flybase.net/reports/FBgn0250821.html "FBgn0037226, FBan0014644, FBgn0045388" protein_coding_gene 0016020=membrane NEST:bs06h05 "IPR001972=Stomatin family, IPR001107=Band 7 protein" CG14644 16-Dec-15 2015_12 FBgn0001659 l(1)ds13 lethal (1) discs small 13 http://flybase.net/reports/FBgn0001659.html gene l(1)1-48 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0038595 CG7142 http://flybase.net/reports/FBgn0038595.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP132 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG7142 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0028031 l(3)S102315 lethal (3) S102315 http://flybase.net/reports/FBgn0028031.html gene 1023/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0025883 sax::tkv sax::tkv http://flybase.net/reports/FBgn0025883.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0260338 GSd429 http://flybase.net/reports/FBgn0260338.html gene 16-Dec-15 2015_12 lethal FBgn0001453 l(1)7Dg lethal (1) 7Dg http://flybase.net/reports/FBgn0001453.html gene "l(1)EM29, EM29" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0002754 mit(1)4 mitotic 4 http://flybase.net/reports/FBgn0002754.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0066373 avg avgust http://flybase.net/reports/FBgn0066373.html gene "0008355=olfactory learning, 0007611=learning or memory" 16-Dec-15 2015_12 memory defective FBgn0002712 mei-G87 meiotic G87 http://flybase.net/reports/FBgn0002712.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiotic cell cycle FBgn0052638 CG32638 http://flybase.net/reports/FBgn0052638.html protein_coding_gene "IPR009436=Angiotensin II, type I receptor-associated" CG32638 16-Dec-15 2015_12 ENSXETG00000013094(agtrap) ENSMUSG00000029007(Agtrap) ENSG00000177674(AGTRAP) FBgn0265012 ed::shg http://flybase.net/reports/FBgn0265012.html engineered_fusion_gene 16-Dec-15 2015_12 "cell adhesion defective,cell autonomous" "wing disc,cell autonomous,somatic clone" FBgn0267967 corolla corolla http://flybase.net/reports/FBgn0267967.html "FBgn0266104, FBgn0030852" protein_coding_gene 0008157=protein phosphatase 1 binding "0010705=meiotic DNA double-strand break processing involved in reciprocal meiotic recombination, 0098653=centromere clustering, 0007130=synaptonemal complex assembly, 0007143=female meiotic division" 0000795=synaptonemal complex "CG8316, mei-39, meiotic 39" CG8316 16-Dec-15 2015_12 FBgn0051361 dpr17 defective proboscis extension response 17 http://flybase.net/reports/FBgn0051361.html "FBgn0037990, FBgn0037991" protein_coding_gene 0007606=sensory perception of chemical stimulus "CT34531, CG14737, CG14738, dpr17, CG31361, Dpr17, Dpr-17" "IPR013106=Immunoglobulin V-set domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG31361 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065272 l(2)SH2056 lethal (2) SH2056 http://flybase.net/reports/FBgn0065272.html gene l(2)SH2 2056 16-Dec-15 2015_12 "lethal,recessive" FBgn0243499 l(3)CC00864 http://flybase.net/reports/FBgn0243499.html gene 16-Dec-15 2015_12 lethal FBgn0004570 blnd bland http://flybase.net/reports/FBgn0004570.html gene 16-Dec-15 2015_12 FBgn0038355 CG4520 http://flybase.net/reports/FBgn0038355.html protein_coding_gene 0055085=transmembrane transport 0005741=mitochondrial outer membrane IPR027246=Eukaryotic porin/Tom40 CG4520 16-Dec-15 2015_12 viable FBgn0038495 CG14336 http://flybase.net/reports/FBgn0038495.html protein_coding_gene 16-Dec-15 2015_12 FBgn0041114 l(3)S028404b lethal (3) S028404b http://flybase.net/reports/FBgn0041114.html gene "l(3)S028404, 0284/04" 16-Dec-15 2015_12 "lethal,recessive" FBgn0032577 CG13244 http://flybase.net/reports/FBgn0032577.html FBgn0063215 protein_coding_gene BcDNA:GH27987 CG13244 16-Dec-15 2015_12 viable FBgn0263458 snoRNA:CG43051-a http://flybase.net/reports/FBgn0263458.html snoRNA_gene snoRNA:bun-a CR43573 16-Dec-15 2015_12 FBgn0022748 anon-E8 anon-E8 http://flybase.net/reports/FBgn0022748.html gene E8 16-Dec-15 2015_12 FBgn0065666 l(2)SH0695 lethal (2) SH0695 http://flybase.net/reports/FBgn0065666.html gene l(2)SH2 0695 16-Dec-15 2015_12 "lethal,recessive" FBgn0034734 CG4554 http://flybase.net/reports/FBgn0034734.html protein_coding_gene 0022008=neurogenesis GM01751p "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR011430=Down-regulated-in-metastasis protein" CG4554 16-Dec-15 2015_12 ENSDARG00000018847(im:7159098) YBL004W(UTP20) ENSMUSG00000004356(Utp20) ENSG00000120800(UTP20) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0011068 l(1)Q21 lethal (1) Q21 http://flybase.net/reports/FBgn0011068.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0263761 CG43678 http://flybase.net/reports/FBgn0263761.html protein_coding_gene CG43678 16-Dec-15 2015_12 FBgn0039367 CG17197 http://flybase.net/reports/FBgn0039367.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005783=endoplasmic reticulum CG17197-PA "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17197 16-Dec-15 2015_12 ENSDARG00000036364(zdhhc24) YOL003C(PFA4) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) viable FBgn0028598 l(2)k04301b lethal (2) k04301b http://flybase.net/reports/FBgn0028598.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028122 l(3)S059011 lethal (3) S059011 http://flybase.net/reports/FBgn0028122.html gene 0590/11 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0083069 ozz ozzie http://flybase.net/reports/FBgn0083069.html gene 0007140=male meiosis 16-Dec-15 2015_12 FBgn0067105 Gë_13F::mira Gë_13F::mira http://flybase.net/reports/FBgn0067105.html engineered_fusion_gene 16-Dec-15 2015_12 spindleb FBgn0060989 l(3)S027614b lethal (3) S027614b http://flybase.net/reports/FBgn0060989.html gene 0276/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0005756 l(1)TK313 lethal (1) TK313 http://flybase.net/reports/FBgn0005756.html gene l313 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0025841 E(var)183-31 E(var)183-31 http://flybase.net/reports/FBgn0025841.html gene "E(var)183/31, E-183/31" 16-Dec-15 2015_12 FBgn0265014 S0279-04 http://flybase.net/reports/FBgn0265014.html gene 16-Dec-15 2015_12 FBgn0053128 CG33128 http://flybase.net/reports/FBgn0053128.html FBgn0031342 protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis "aspartic-type endopeptidase, CG10872" "IPR001461=Aspartic peptidase, IPR021109=Aspartic peptidase domain, IPR001969=Aspartic peptidase, active site" CG33128 16-Dec-15 2015_12 "ENSMUSG00000023987(Pgc),ENSMUSG00000004552(Ctse)" "ENSG00000204973,ENSG00000172647,ENSG00000180860,ENSG00000196188(CTSE),ENSG00000096088(PGC)" viable FBgn0064912 CG31178 http://flybase.net/reports/FBgn0064912.html "FBgn0038911, FBgn0045771, FBgn0051178" protein_coding_gene "CG13414, BcDNA:LP09246, Dromel_CG31178_FBtr0084138_mORF, CT32770, BEST:LP09246, Tes87" IPR019537=Transmembrane protein 65 CG31178 16-Dec-15 2015_12 viable FBgn0024261 acd(2)5M8 auditory courtship defective 5M8 http://flybase.net/reports/FBgn0024261.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective,courtship behavior defective,male sterile" FBgn0028507 CG3793 http://flybase.net/reports/FBgn0028507.html FBgn0027891 protein_coding_gene 0008168=methyltransferase activity 0032259=methylation BG:DS09217.4 "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR016651=Leucine carboxyl methyltransferase 1, LCMT1, IPR007213=Leucine carboxyl methyltransferase" CG3793 16-Dec-15 2015_12 ENSDARG00000045140(lcmt1) YDR435C(PPM1) WBGene00007137(B0285.4) ENSMUSG00000030763(Lcmt1) ENSG00000205629(LCMT1) "viable,fertile" FBgn0016832 l(1)MZ19 lethal (1) MZ19 http://flybase.net/reports/FBgn0016832.html gene M19 16-Dec-15 2015_12 "lethal,recessive" FBgn0266495 s-116 http://flybase.net/reports/FBgn0266495.html gene 16-Dec-15 2015_12 FBgn0267177 CR45617 http://flybase.net/reports/FBgn0267177.html non_protein_coding_gene CR45617 16-Dec-15 2015_12 FBgn0038656 CG14294 http://flybase.net/reports/FBgn0038656.html FBgn0047343 protein_coding_gene BcDNA:AT18358 CG14294 16-Dec-15 2015_12 FBgn0035697 CG10163 http://flybase.net/reports/FBgn0035697.html protein_coding_gene 0008970=phosphatidylcholine 1-acylhydrolase activity "0008360=regulation of cell shape, 0007155=cell adhesion" "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG10163 16-Dec-15 2015_12 viable FBgn0266129 lov jim lovell http://flybase.net/reports/FBgn0266129.html "FBgn0067632, FBgn0003715, FBgn0004900, FBgn0012045, FBgn0035093" protein_coding_gene 0003677=DNA binding "0008049=male courtship behavior, 0031987=locomotion involved in locomotory behavior, 0042332=gravitaxis, 0030536=larval feeding behavior, 0048060=negative gravitaxis, 0007418=ventral midline development, 0048477=oogenesis, 0008346=larval walking behavior" "CG16778, Tkr, anon-G2, Tyrosine kinase-related protein, dTKR, BTB-protein-III, Tyrosine kinase-related, Tyrosine kinase related, BtbIII, TKR, 91Y, Jim Lovell, g2, 091y, tkr, BTB-III, CG2672, Lov" "IPR009057=Homeodomain-like, IPR011333=POZ domain, IPR007889=DNA binding HTH domain, Psq-type, IPR000210=BTB/POZ domain" CG16778 16-Dec-15 2015_12 embryonic stage | stage 4-10 organism | dorso-lateral

FBgn0031197 CG17601 http://flybase.net/reports/FBgn0031197.html protein_coding_gene CG17601 16-Dec-15 2015_12 viable FBgn0033963 CG12857 http://flybase.net/reports/FBgn0033963.html protein_coding_gene "IPR011333=POZ domain, IPR011705=BTB/Kelch-associated" CG12857 16-Dec-15 2015_12 "viable,fertile" FBgn0051070 tRNA:CR31070 transfer RNA:CR31070 http://flybase.net/reports/FBgn0051070.html FBgn0060099 tRNA_gene 0033427=CAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3R.trna40-GlnTTG, tRNA:Q:TTG:AE002708-a, AE002708.trna34-GlnTTG, CR31070" CR31070 16-Dec-15 2015_12 FBgn0051436 CG31436 http://flybase.net/reports/FBgn0051436.html FBgn0039320 protein_coding_gene CG13660 "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG31436 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" "visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0021798 l(2)k17002 lethal (2) k17002 http://flybase.net/reports/FBgn0021798.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265196 CR44256 http://flybase.net/reports/FBgn0265196.html non_protein_coding_gene CR44256 16-Dec-15 2015_12 FBgn0031617 CG15635 http://flybase.net/reports/FBgn0031617.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG15635 16-Dec-15 2015_12 "viable,fertile" FBgn0060577 l(3)S095209 lethal (3) S095209 http://flybase.net/reports/FBgn0060577.html gene 0952/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0084445 EP2012 EP2012 http://flybase.net/reports/FBgn0084445.html gene 16-Dec-15 2015_12 FBgn0030690 CG12383 http://flybase.net/reports/FBgn0030690.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085396 CG34367 http://flybase.net/reports/FBgn0085396.html "FBgn0032226, FBgn0032227" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG13141, CG5369" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR003654=OAR domain, IPR000047=Helix-turn-helix motif" CG34367 16-Dec-15 2015_12 "ENSDARG00000008869(shox2),ENSDARG00000025891(shox)" "ENSXETG00000014058(SHOX2),ENSXETG00000016879(SHOX)" ENSMUSG00000027833(Shox2) "ENSG00000168779(SHOX2),ENSG00000185960(SHOX)" FBgn0263757 Rpb4 http://flybase.net/reports/FBgn0263757.html "FBgn0053520, FBgn0038591, FBgn0051237, FBgn0062038, FBgn0263737" protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0005515=protein binding, 0000166=nucleotide binding" "0007095=mitotic G2 DNA damage checkpoint, 0022008=neurogenesis, 0006366=transcription from RNA polymerase II promoter, 0035079=polytene chromosome puffing" "0005705=polytene chromosome interband, 0005700=polytene chromosome, 0016591=DNA-directed RNA polymerase II, holoenzyme, 0005701=polytene chromosome chromocenter, 0005665=DNA-directed RNA polymerase II, core complex, 0005634=nucleus" "dRPB4, dAda2a, DmRPB4, CG33520, CG7150, Rpb4, dRpb4, DmRpb4, Ada2a, RPB4, CG31237" "IPR010997=HRDC-like, IPR005574=RNA polymerase II, Rpb4, IPR006590=RNA polymerase II, Rpb4, core" CG43662 16-Dec-15 2015_12 "viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,neuroanatomy defective" "ganglion mother cell,intestinal stem cell" FBgn0264385 CR43837 http://flybase.net/reports/FBgn0264385.html non_protein_coding_gene CR43837 16-Dec-15 2015_12 FBgn0261567 CG42681 http://flybase.net/reports/FBgn0261567.html protein_coding_gene CG42681 16-Dec-15 2015_12 FBgn0030244 CG2157 http://flybase.net/reports/FBgn0030244.html protein_coding_gene CG2157 16-Dec-15 2015_12 FBgn0001907 l(2)24De lethal (2) 24De http://flybase.net/reports/FBgn0001907.html gene "l(2)jf3, jf3" 16-Dec-15 2015_12 lethal FBgn0265976 CR44755 http://flybase.net/reports/FBgn0265976.html non_protein_coding_gene CR44755 16-Dec-15 2015_12 FBgn0030740 CG9917 http://flybase.net/reports/FBgn0030740.html FBgn0044642 protein_coding_gene anon-WO0140519.229 IPR009832=Protein of unknown function DUF1397 CG9917 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0028168 l(3)S027707 lethal (3) S027707 http://flybase.net/reports/FBgn0028168.html gene 0277/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0265311 CR44284 http://flybase.net/reports/FBgn0265311.html non_protein_coding_gene CR44284 16-Dec-15 2015_12 FBgn0036680 Cpr73D Cuticular protein 73D http://flybase.net/reports/FBgn0036680.html "FBtr0075298, FBpp0075058" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG9665 IPR000618=Insect cuticle protein CG9665 16-Dec-15 2015_12 viable FBgn0053798 CG33798 http://flybase.net/reports/FBgn0053798.html FBgn0082867 protein_coding_gene "unnamed, BP1039" IPR010512=Protein of unknown function DUF1091 CG33798 16-Dec-15 2015_12 viable FBgn0034479 CG8654 http://flybase.net/reports/FBgn0034479.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG8654 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0266249 CR44944 http://flybase.net/reports/FBgn0266249.html non_protein_coding_gene lincRNA.783 CR44944 16-Dec-15 2015_12 FBgn0002383 l(3)93Cc lethal (3) 93Cc http://flybase.net/reports/FBgn0002383.html gene "l(3)er14, er14" 16-Dec-15 2015_12 "lethal,recessive" FBgn0028740 CG6362 http://flybase.net/reports/FBgn0028740.html protein_coding_gene EG:52C10.6 CG6362 16-Dec-15 2015_12 viable FBgn0041612 X-element\ORF2 ORF2 http://flybase.net/reports/FBgn0041612.html transposable_element_gene 0003964=RNA-directed DNA polymerase activity "0006313=transposition, DNA-mediated" "RT, ORF2" "IPR000477=Reverse transcriptase domain, IPR005135=Endonuclease/exonuclease/phosphatase" 16-Dec-15 2015_12 FBgn0067760 l(1)G0019 lethal (1) G0019 http://flybase.net/reports/FBgn0067760.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0043862 pf-4 pairing failure-4 http://flybase.net/reports/FBgn0043862.html gene 0007141=male meiosis I "CG4, Complementation group 4" 16-Dec-15 2015_12 FBgn0003912 Tyr3 Tyrosine 3 http://flybase.net/reports/FBgn0003912.html gene "Tyr-3, Tyrosinase, Tyrosinase-3, tyrosinase" 16-Dec-15 2015_12 FBgn0085200 CG34171 http://flybase.net/reports/FBgn0085200.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG34171 16-Dec-15 2015_12 FBgn0000800 fs(1)de11 female sterile (1) defective eggs 11 http://flybase.net/reports/FBgn0000800.html gene de11 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion" FBgn0040882 CG15045 http://flybase.net/reports/FBgn0040882.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035344 Cyp4d20 Cyp4d20 http://flybase.net/reports/FBgn0035344.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "4d20, CG16761, RH59895" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG16761 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0260789 mxc multi sex combs http://flybase.net/reports/FBgn0260789.html "FBgn0005639, FBgn0001798, FBgn0030113, FBgn0030112" protein_coding_gene 0003677=DNA binding "0042386=hemocyte differentiation, 0035172=hemocyte proliferation, 0030097=hemopoiesis, 0022008=neurogenesis, 0046331=lateral inhibition" 0035363=histone locus body "MXC, MPM2, Mxc, CG12058, lethal(1)malignant blood neoplasm, NPAT, CG12124, l(1)mbn, dNPAT" "IPR017956=AT hook, DNA-binding motif, IPR006594=LIS1 homology motif" CG12124 16-Dec-15 2015_12 ENSMUSG00000033054(Npat) ENSG00000149308(NPAT) FBgn0027785 NP15.6 NP15.6 http://flybase.net/reports/FBgn0027785.html FBgn0062121 protein_coding_gene 0022904=respiratory electron transport chain 0005747=mitochondrial respiratory chain complex I "anon-WO0118547.281, CG6008" "IPR019329=NADH:ubiquinone oxidoreductase, ESSS subunit" CG6008 16-Dec-15 2015_12 ENSDARG00000043467(si:dkey-6n6.4) "ENSMUSG00000031059(Ndufb11),ENSMUSG00000061633(1700029P11Rik)" ENSG00000147123(NDUFB11) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0026242 fuzzy-cellularization fuzzy cellularization http://flybase.net/reports/FBgn0026242.html gene 16-Dec-15 2015_12 FBgn0030869 Socs16D Suppressor of Cytokine Signaling at 16D http://flybase.net/reports/FBgn0030869.html protein_coding_gene 0017022=myosin binding 0038202=TORC1 signaling "Suppressor of Cytokine Signaling at 16E, SOCS16D, Socs16E, SOCS, socs16D, CG8146, dmSocs16D, Socs 16D" "IPR000980=SH2 domain, IPR028413=Suppressor of cytokine signalling, IPR028423=Suppressor of cytokine signalling 7, IPR001496=SOCS box domain" CG8146 16-Dec-15 2015_12 ENSMUSG00000038485(Socs7) ENSG00000174111(SOCS7) "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0025369 Hemagglutinin Hemagglutinin http://flybase.net/reports/FBgn0025369.html gene hemagglutinin 16-Dec-15 2015_12 FBgn0002277 l(3)73Ab lethal (3) 73Ab http://flybase.net/reports/FBgn0002277.html gene "l(3)133.37, l(3)133.10, l(3)std37" 16-Dec-15 2015_12 "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" FBgn0086660 snoRNA:ë¬28S-1837a snoRNA:ë¬28S-1837a http://flybase.net/reports/FBgn0086660.html "FBgn0065079, FBgn0082996, FBgn0053652" snoRNA_gene 0005730=nucleolus "snoRNA:11, Psi 28S-1837a(SnoR14), Dm-14, CR33652, Psi28S-1837a, psi28S-1837a, snoRNA:14, snoR14" CR33652 16-Dec-15 2015_12 FBgn0046336 da::twi da::twi http://flybase.net/reports/FBgn0046336.html engineered_fusion_gene Twi-Da 16-Dec-15 2015_12 "embryonic somatic muscle,embryonic/larval visceral muscle,presumptive embryonic salivary gland" FBgn0003225 rea rearranged tergites http://flybase.net/reports/FBgn0003225.html gene 16-Dec-15 2015_12 "visible,recessive,viable,reduced,fertile" tergite FBgn0003627 Su(var)316 Suppressor of variegation 316 http://flybase.net/reports/FBgn0003627.html gene "316, Su-var(3)316, Su(var)3-316" 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0039668 Trc8 TRC8 ortholog http://flybase.net/reports/FBgn0039668.html FBgn0062836 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0005515=protein binding, 0008270=zinc ion binding" "0007418=ventral midline development, 0016567=protein ubiquitination, 0045926=negative regulation of growth" 0005783=endoplasmic reticulum "TRC8, Dtrc8, Trc8, CG2304, DTrc8" "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR025754=TRC8 N-terminal domain" CG2304 16-Dec-15 2015_12 ENSDARG00000036929(zgc:175173) WBGene00022471(Y119C1B.5) ENSXETG00000017487(rnf139) ENSMUSG00000037075(Rnf139) ENSG00000170881(RNF139) "size defective,lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable" "wing,eye" FBgn0003937 snRNA:U5:39B small nuclear RNA U5 at 39B http://flybase.net/reports/FBgn0003937.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" "U5 small nuclear RNA, U5snRNA39B, U5 snRNA, U5, small nuclear RNA U5, snRNA[[3]], dU5, snRNA:U5, snRNA4, K2, U5 snRNA 39B, U5snRNA, snRNA3" 16-Dec-15 2015_12 FBgn0038751 CG4770 http://flybase.net/reports/FBgn0038751.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase, IPR016040=NAD(P)-binding domain" CG4770 16-Dec-15 2015_12 viable FBgn0027649 l(2)CL-L lethal (2) Cell Lethal Left http://flybase.net/reports/FBgn0027649.html gene CL2L 16-Dec-15 2015_12 lethal FBgn0051910 CG31910 http://flybase.net/reports/FBgn0051910.html "FBgn0045355, FBgn0063718" protein_coding_gene "BcDNA:AT21561, NEST:bs09e03" CG31910 16-Dec-15 2015_12 viable DRSC00946 E -0.084424284 -0.541682233 -1.724448191 0.300547712 0.063334014 -1.272003118 FBgn0035171 CG12502 http://flybase.net/reports/FBgn0035171.html protein_coding_gene "IPR018787=Protein of unknown function DUF2371, TMEM200" CG12502 16-Dec-15 2015_12 viable FBgn0037857 Tengl4 Testis EndoG-Like 4 http://flybase.net/reports/FBgn0037857.html protein_coding_gene "0004519=endonuclease activity, 0003676=nucleic acid binding, 0046872=metal ion binding" CG4683 "IPR020821=Extracellular Endonuclease, subunit A, IPR001604=DNA/RNA non-specific endonuclease" CG4683 16-Dec-15 2015_12 "viable,fertile" FBgn0004759 l(3)89Bl lethal (3) 89Bl http://flybase.net/reports/FBgn0004759.html gene 16-Dec-15 2015_12 lethal FBgn0267484 CR45834 http://flybase.net/reports/FBgn0267484.html non_protein_coding_gene CR45834 16-Dec-15 2015_12 FBgn0000941 fs(2)A11 female sterile (2) A11 http://flybase.net/reports/FBgn0000941.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" "female reproductive system,maternal effect" FBgn0038737 CG11447 http://flybase.net/reports/FBgn0038737.html protein_coding_gene 0008650=rRNA (uridine-2'-O-)-methyltransferase activity 0001510=RNA methylation "IPR002877=Ribosomal RNA methyltransferase FtsJ domain, IPR015507=Ribosomal RNA large subunit methyltransferase E, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG11447 16-Dec-15 2015_12 YGL136C(MRM2) WBGene00009735(F45G2.9) ENSXETG00000012559(FTSJ2) ENSMUSG00000029557(Ftsj2) ENSG00000122687(FTSJ2) viable DRSC27849 K -0.849467673 -0.254383549 -0.879631263 0.549433847 -2.00294258 0.074928742 FBgn0010652 l(2)08770 lethal (2) 08770 http://flybase.net/reports/FBgn0010652.html FBgn0022199 gene l(2)k04808 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" "crystal cell,plasmatocyte" FBgn0031729 CG12511 http://flybase.net/reports/FBgn0031729.html protein_coding_gene IPR007014=FUN14 CG12511 16-Dec-15 2015_12 ENSXETG00000004831(FUNDC1) "ENSG00000069509(FUNDC1),ENSG00000165775(FUNDC2),ENSG00000182814" viable FBgn0044407 Scim20 Sensitized chromosome inheritance modifier 20 http://flybase.net/reports/FBgn0044407.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0030764 CG9777 http://flybase.net/reports/FBgn0030764.html protein_coding_gene CG9777 16-Dec-15 2015_12 viable FBgn0000150 awd abnormal wing discs http://flybase.net/reports/FBgn0000150.html "FBgn0011322, FBgn0024573, FBgn0025960, FBgn0046351, FBgn0046352, FBgn0062949, FBgn0064938" protein_coding_gene "0005525=GTP binding, 0000287=magnesium ion binding, 0004550=nucleoside diphosphate kinase activity, 0008017=microtubule binding, 0016301=kinase activity, 0005524=ATP binding" "0006241=CTP biosynthetic process, 0007017=microtubule-based process, 0035152=regulation of tube architecture, open tracheal system, 0018105=peptidyl-serine phosphorylation, 0006468=protein phosphorylation, 0016334=establishment or maintenance of polarity of follicular epithelium, 0046777=protein autophosphorylation, 0006165=nucleoside diphosphate phosphorylation, 0007424=open tracheal system development, 0007427=epithelial cell migration, open tracheal system, 0006228=UTP biosynthetic process, 0034332=adherens junction organization, 0006183=GTP biosynthetic process, 0007067=mitotic nuclear division" "0005874=microtubule, 0005875=microtubule associated complex, 0005886=plasma membrane" "clone 2.27, 1084/08, Killer of prune, NDKB, K-pn, Nucleoside diphosphate kinase, e(shi)A, Abnormal wings disc, nucleoside diphosphate kinase, abnormal wing disc, BcDNA:GM19775, l(3)L8700, killer of prune, CG2210, NDPK, anon-EST:Liang-2.27, BcDNA:RH27794, NDP kinase, eshiA, anon-WO0172774.82, anon-EST:Liang-2.28, Killer-of-prune, clone 2.28, anon-WO0172774.80, Awd, l(3)j2A4, Nm23/awd, Kpn" "IPR001564=Nucleoside diphosphate kinase, IPR023005=Nucleoside diphosphate kinase, active site" CG2210 16-Dec-15 2015_12 ENSDARG00000043820 YKL067W(YNK1) WBGene00009119(F25H2.5) ENSXETG00000011340(nme1(prov)) "ENSMUSG00000020857(Nme2),ENSMUSG00000037601(Nme1)" ENSG00000011052(NME2) " embryonic stage -- adult stage , larval stage | third instar , larval stage | second instar " dorsal mesothoracic disc | restricted

" embryonic stage -- adult stage , larval stage | third instar " dorsal mesothoracic disc

"lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,wild-type,lethal - all die before end of P-stage,some die during pharate adult stage,paralytic,heat sensitive" "egg chamber,heat sensitive,follicle cell,presumptive embryonic/larval tracheal system,dorsal group branch precursor,embryonic dorsal group branch & filopodium,somatic clone,dorsal trunk primordium,embryonic/larval tracheal system,embryonic/larval dorsal trunk,photoreceptor cell,optic cartridge" DRSC16906 I 1.536600582 -0.270013002 -0.802434165 0.352023911 0.873164603 -0.958697643 FBgn0053093 CG33093 http://flybase.net/reports/FBgn0053093.html FBgn0038982 protein_coding_gene "0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 0055114=oxidation-reduction process CG5340 "IPR027443=Isopenicillin N synthase-like, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR026992=Non-haem dioxygenase N-terminal domain" CG33093 16-Dec-15 2015_12 viable FBgn0013230 E(var)1817 E(var)1817 http://flybase.net/reports/FBgn0013230.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0053966 CG33966 http://flybase.net/reports/FBgn0053966.html FBgn0035191 protein_coding_gene "0005215=transporter activity, 0008431=vitamin E binding" 0006810=transport 0005622=intracellular CG1211 "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG33966 16-Dec-15 2015_12 viable FBgn0061475 18SrRNA 18SrRNA http://flybase.net/reports/FBgn0061475.html "FBgn0045764, FBgn0045774, FBgn0045784, FBgn0045790, FBgn0045822, FBgn0045824, FBgn0046105" rRNA_gene 0022627=cytosolic small ribosomal subunit "CR40959, 18S RNA, NEST:bs01c01, BEST:LP07011, 18SRNA, 18 S rRNA, BEST:SD07466, 18s rRNA, BEST:GH11893, BEST:LD33742, BEST:LD10585, BEST:GH15369, 18S, 18S rDNA, 18S rRNA" 16-Dec-15 2015_12 "viable,fertile" FBgn0003618 Su(var)2-37 Suppressor of variegation 2-37 http://flybase.net/reports/FBgn0003618.html gene 16-Dec-15 2015_12 FBgn0082365 EP3683 EP3683 http://flybase.net/reports/FBgn0082365.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0033658 TwdlëÕ TwdlëÕ http://flybase.net/reports/FBgn0033658.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix "CT25838, TwdlBeta, CG8986" IPR004145=Domain of unknown function DUF243 CG8986 16-Dec-15 2015_12 FBgn0031235 CG13693 http://flybase.net/reports/FBgn0031235.html protein_coding_gene IPR025254=Domain of unknown function DUF4201 CG13693 16-Dec-15 2015_12 ENSDARG00000006981(ccdc113) ENSXETG00000013739(Q5HZC9_XENTR) ENSMUSG00000036598(Ccdc113) ENSG00000103021(CCDC113) viable FBgn0034485 CG11099 http://flybase.net/reports/FBgn0034485.html protein_coding_gene CT31033 IPR001611=Leucine-rich repeat CG11099 16-Dec-15 2015_12 ENSXETG00000025913(LRRC69) ENSG00000165383(LRRC18) viable FBgn0017392 l(1)15Bb lethal (1) 15Bb http://flybase.net/reports/FBgn0017392.html gene 16-Dec-15 2015_12 lethal FBgn0262649 l(2)47A7 lethal (2) 47A7 http://flybase.net/reports/FBgn0262649.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010355 Taf1 TBP-associated factor 1 http://flybase.net/reports/FBgn0010355.html "FBgn0004775, FBgn0010420, FBgn0016735" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0004672=protein kinase activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding, 0001129=TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly, 0004402=histone acetyltransferase activity, 0008134=transcription factor binding, 0008270=zinc ion binding" "0006367=transcription initiation from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006468=protein phosphorylation, 0016573=histone acetylation, 0007221=positive regulation of transcription of Notch receptor target, 0006355=regulation of transcription, DNA-templated, 0051726=regulation of cell cycle, 0022008=neurogenesis, 0046425=regulation of JAK-STAT cascade, 0006461=protein complex assembly" "0005634=nucleus, 0005669=transcription factor TFIID complex, 0005654=nucleoplasm, 0005730=nucleolus" "Taf1p, cell, TAF230, cel, TAF[[II]]250/230, l(3)84Ab, dmTAF1, TAFII-250, TAFII250, cell lethal, TAF[[II]]250, Taf200, p230, TAF[II]250, TAF250, dTAF230, unnamed, Taf[[II]]250, TAF200, TFIID 230 kda subunit, TAF250/230, TAF1, TAF[[II]], TATA-associated factor 250, TAF[[II]]230, CG17603, dTAF[[II]]250, dTAF[[II]]230, Taf250, TFIID TAF250, SR3-5, TBP-associated factor 250kD, Suppressor of Ras85D 3-5, BG:DS00004.13, dTAF250, EfW1, TBP-associated factor 250, d230, TFIID, dmTAF[[II]]230, TAF, dTAFII250, Taf230, TBP-associated factor" "IPR018359=Bromodomain, conserved site, IPR009067=TAFII-230 TBP-binding, IPR011177=Transcription initiation factor TFIID subunit 1, animal, IPR022591=Transcription initiation factor TFIID subunit 1, domain of unknown function, IPR017956=AT hook, DNA-binding motif, IPR001878=Zinc finger, CCHC-type, IPR001487=Bromodomain" CG17603 16-Dec-15 2015_12 ENSDARG00000035330(taf1) YGR274C(TAF1) WBGene00006382(taf-1) ENSXETG00000023137() ENSMUSG00000031314(Taf1) "ENSG00000147133(TAF1),ENSG00000122728(TAF1L)" "viable,lethal,recessive,partially lethal - majority die,female sterile,lethal - all die before end of larval stage,cell autonomous,some die during larval stage,neuroanatomy defective,visible,some die during pupal stage" "ocellus,oocyte,interommatidial bristle,eye photoreceptor cell,macrochaeta,microchaeta,male terminalia,wing vein L4,wing,ovary,egg chamber,second instar larva,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC12607 IK -2.129191124 0.841473644 -1.452006797 -0.506402004 2.130553819 2.755929324 FBgn0264598 PsGEF Protostome-specific GEF http://flybase.net/reports/FBgn0264598.html "FBgn0040387, FBgn0029616, FBgn0040386, FBgn0040390, FBgn0029615" protein_coding_gene "0005544=calcium-dependent phospholipid binding, 0005089=Rho guanyl-nucleotide exchange factor activity" "0035023=regulation of Rho protein signal transduction, 0030833=regulation of actin filament polymerization, 0016319=mushroom body development, 1900029=positive regulation of ruffle assembly, 0035022=positive regulation of Rac protein signal transduction" 0005622=intracellular "CG43947, CG14045, EG:BACH48C10.4, EG:BACH7M4.1, CG14047, null, PsGef, DmPsGEF, EG:BACH7M4.2, FBgn0264598, protostome-specific GEF" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000008=C2 domain, IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain, IPR001478=PDZ domain" CG43947 16-Dec-15 2015_12 DRSC18596 E 0.906126963 0.259884469 2.935523645 0.712665742 -1.139385265 -0.177717615 FBgn0039730 CG7903 http://flybase.net/reports/FBgn0039730.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" cg7903 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG7903 16-Dec-15 2015_12 "ENSXETG00000017729(RALYL),ENSXETG00000016162(hnrpc)" FBgn0000264 Cubl Curled blistered http://flybase.net/reports/FBgn0000264.html gene Cb 16-Dec-15 2015_12 wing FBgn0061084 l(3)S012225a lethal (3) S012225a http://flybase.net/reports/FBgn0061084.html gene 0122/25 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260305 GSd315 http://flybase.net/reports/FBgn0260305.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,bouton" FBgn0259853 Su(Ste):CR42422 Su(Ste):CR42422 http://flybase.net/reports/FBgn0259853.html non_protein_coding_gene "CR42422, RR41835" CR42422 16-Dec-15 2015_12 FBgn0001497 l(1)10Bk lethal (1) 10Bk http://flybase.net/reports/FBgn0001497.html gene "3, 10Bk" 16-Dec-15 2015_12 "lethal,recessive,polyphasic,germline clone,maternal effect" FBgn0029525 CG18273 http://flybase.net/reports/FBgn0029525.html FBgn0023533 protein_coding_gene 0022008=neurogenesis "EG:171D11.6, CG13372" "IPR018849=Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal" CG18273 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0039522 CG13972 http://flybase.net/reports/FBgn0039522.html protein_coding_gene "IPR000048=IQ motif, EF-hand binding site" CG13972 16-Dec-15 2015_12 ENSDARG00000068678(si:ch211-222m18.3) ENSMUSG00000035578(Iqcg) ENSG00000114473(IQCG) viable FBgn0066129 E(sda)D E(sda)D http://flybase.net/reports/FBgn0066129.html gene "0009612=response to mechanical stimulus, 0007638=mechanosensory behavior" Line D 16-Dec-15 2015_12 bang sensitive FBgn0262233 mir-2494 mir-2494 stem loop http://flybase.net/reports/FBgn0262233.html miRNA_gene "CR42940, dme-miR-2494-5p, dme-mir-2494" CR42940 16-Dec-15 2015_12 viable FBgn0032836 CG10680 http://flybase.net/reports/FBgn0032836.html protein_coding_gene CG10680 16-Dec-15 2015_12 viable FBgn0039678 Obp99a Odorant-binding protein 99a http://flybase.net/reports/FBgn0039678.html FBgn0062910 protein_coding_gene 0005549=odorant binding "0042048=olfactory behavior, 0019236=response to pheromone, 0007606=sensory perception of chemical stimulus" "0012505=endomembrane system, 0005576=extracellular region" "DmelObp99a, BcDNA:RH70762, Odorant binding protein 99a, 99a, CG18111, OBP99a" IPR006170=Pheromone/general odorant binding protein CG18111 16-Dec-15 2015_12 FBgn0035010 CG13579 http://flybase.net/reports/FBgn0035010.html "FBgn0046585, FBgn0046586" protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.151, anon-WO0170980.152" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG13579 16-Dec-15 2015_12 "viable,fertile,oxidative stress response defective,visible" trichogen cell FBgn0040077 primo-1 primo-1 http://flybase.net/reports/FBgn0040077.html "FBgn0038174, FBgn0051311, FBgn0053748, FBtr0082839, FBpp0082304, FBtr0082840, FBpp0082305, FBtr0082841, FBpp0082306, FBtr0082842, FBpp0082307, FBtr0082843, FBpp0082308" protein_coding_gene "0004726=non-membrane spanning protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0003993=acid phosphatase activity" 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" "CG33748, CG9599, CG31311, Primo-1, BEO2, LMW-PTP, primo" "IPR023485=Phosphotyrosine protein phosphatase I superfamily, IPR017867=Protein-tyrosine phosphatase, low molecular weight, IPR002115=Protein-tyrosine phosphatase, low molecular weight, mammalian" CG33748 16-Dec-15 2015_12 "ENSDARG00000070328(acp1),ENSDARG00000003891(LOC100330515)" YPR073C(LTP1) WBGene00022379(Y94H6A.7) ENSXETG00000027987(Q6DEU0_XENTR) ENSMUSG00000044573(Acp1) ENSG00000143727(ACP1) " pupal stage | stage P8 , pupal stage , larval stage , pupal stage | stage P6 , adult stage " " primary pigment cell

, cone cell

" "viable,fertile" FBgn0262314 mir-978 mir-978 stem loop http://flybase.net/reports/FBgn0262314.html miRNA_gene "CR43021, miR-978, dme-mir-978" CR43021 16-Dec-15 2015_12 "visible,lethal" wing FBgn0028543 NimB2 Nimrod B2 http://flybase.net/reports/FBgn0028543.html "FBgn0027908, FBgn0051839" protein_coding_gene "0007498=mesoderm development, 0042742=defense response to bacterium" 0005576=extracellular region "CT37470, nimrod B2, CG16882, nimrodB2, nimB2, BG:DS00180.7, CG31839, DS00180.7, NimB2" "IPR000742=EGF-like domain, IPR003341=Cysteine rich repeat, tripleX, IPR009030=Insulin-like growth factor binding protein, N-terminal" CG31839 16-Dec-15 2015_12 "ENSDARG00000038208,ENSDARG00000028168" ENSXETG00000011331(VWDE) viable FBgn0261089 Sytë± Synaptotagmin ë± http://flybase.net/reports/FBgn0261089.html "FBgn0032653, FBgn0085002, FBgn0261087, FBgn0042690" protein_coding_gene 0005544=calcium-dependent phospholipid binding "0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport" "0016021=integral component of membrane, 0005886=plasma membrane" "Syt alpha, SYT3, unnamed, Syt3, CG5559, dsytalpha, Sytalpha, sytalpha, SYT-alpha" IPR000008=C2 domain CG5559 16-Dec-15 2015_12 FBgn0031600 CG3652 http://flybase.net/reports/FBgn0031600.html protein_coding_gene 0016020=membrane IPR006977=Yip1 domain CG3652 16-Dec-15 2015_12 ENSDARG00000054433(yipf6) YGL198W(YIP4) WBGene00012208(W02D9.2) ENSXETG00000005093(TGas105o14.1) ENSMUSG00000047694(Yipf6) ENSG00000181704(YIPF6) viable FBgn0034073 CG8414 http://flybase.net/reports/FBgn0034073.html protein_coding_gene 0051731=polynucleotide 5'-hydroxyl-kinase activity 0006364=rRNA processing IPR027417=P-loop containing nucleoside triphosphate hydrolase CG8414 16-Dec-15 2015_12 ENSMUSG00000028948(Nol9) ENSG00000162408(NOL9) "lethal,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001073 Fs(3)Zom Female sterile (3) Zombor http://flybase.net/reports/FBgn0001073.html gene 0007344=pronuclear fusion "Zom, Fs(3)Zombor, Fs(3)Sz26" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus | maternal effect,female pronucleus | maternal effect" FBgn0020876 anon-G36 anon-G36 http://flybase.net/reports/FBgn0020876.html gene "2-G36, 2-P50" 16-Dec-15 2015_12 "chemical sensitive,recessive,fertile" FBgn0010205 l(1)GSB lethal (1) GSB http://flybase.net/reports/FBgn0010205.html gene 16-Dec-15 2015_12 FBgn0003625 Su(var)309 Suppressor of variegation 309 http://flybase.net/reports/FBgn0003625.html gene 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant" FBgn0065592 l(2)SH0897 lethal (2) SH0897 http://flybase.net/reports/FBgn0065592.html gene l(2)SH2 0897 16-Dec-15 2015_12 "lethal,recessive" FBgn0036393 CG17362 http://flybase.net/reports/FBgn0036393.html protein_coding_gene CG17362 16-Dec-15 2015_12 viable FBgn0036710 CG6479 http://flybase.net/reports/FBgn0036710.html protein_coding_gene 0006909=phagocytosis IPR019176=Cytochrome B561-related CG6479 16-Dec-15 2015_12 ENSDARG00000039340(LOC555279) WBGene00007186(B0464.6) ENSXETG00000016299(TMEM209) ENSMUSG00000029782(Tmem209) ENSG00000146842(TMEM209) "immune response defective,viable,visible,body color defective" mesothoracic tergum DRSC10647 EK 0.096895975 -0.865872244 0.321626598 -1.516851023 1.515679083 0.314707782 FBgn0069329 X-115-40 X-115-40 http://flybase.net/reports/FBgn0069329.html gene 0007399=nervous system development 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,neurogenic phenotype,recessive,some die during embryonic stage" FBgn0040684 CG12589 http://flybase.net/reports/FBgn0040684.html protein_coding_gene CG12589 16-Dec-15 2015_12 viable FBgn0011953 tRNA:R:12Ef transfer RNA:arg:12Ef http://flybase.net/reports/FBgn0011953.html "FBgn0011947, FBgn0052610, FBgn0060084" tRNA_gene 0033431=CGA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chrX.trna21-ArgTCG, CR32610, tRNA:R:TCG:AE002593, tRNA:arg12Ef, ArgDm, AE002593.trna12-ArgTCG, tRNA[arg], tRNA:R1, transfer RNA:arg1, tRNA:arg1, tRNA:arg12DE" CR32610 16-Dec-15 2015_12 FBgn0004540 l(4)102EFd lethal (4) 102EFd http://flybase.net/reports/FBgn0004540.html gene l(4)39 16-Dec-15 2015_12 "lethal,recessive" FBgn0043989 Su(rst)E124 Su(rst)E124 http://flybase.net/reports/FBgn0043989.html gene 0001745=compound eye morphogenesis E124 16-Dec-15 2015_12 FBgn0041784 S(Sev-CycE)D2 S(Sev-CycE)D2 http://flybase.net/reports/FBgn0041784.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038566 CG14317 http://flybase.net/reports/FBgn0038566.html FBgn0046341 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex anon-WO0172774.95 CG14317 16-Dec-15 2015_12 viable FBgn0031558 CG16704 http://flybase.net/reports/FBgn0031558.html FBgn0047025 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "CT37177, BcDNA:RH31195" "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG16704 16-Dec-15 2015_12 ENSDARG00000069736 ENSXETG00000016886(SPINT3) "ENSMUSG00000074595(Wfdc6a),ENSMUSG00000070531(Wfdc6b),ENSMUSG00000017733(Spinlw1)" viable FBgn0037562 CG11671 http://flybase.net/reports/FBgn0037562.html FBgn0063189 protein_coding_gene 0050905=neuromuscular process BcDNA:GM23845 CG11671 16-Dec-15 2015_12 "ENSDARG00000058857,ENSDARG00000018532(zgc:101715),ENSDARG00000068408" ENSXETG00000010474(Q6DJ35_XENTR) ENSMUSG00000054676(1600014C10Rik) ENSG00000131943(C19orf12) viable FBgn0065257 l(2)SH2103 lethal (2) SH2103 http://flybase.net/reports/FBgn0065257.html gene l(2)SH2 2103 16-Dec-15 2015_12 "lethal,recessive" FBgn0011695 EbpIII Ejaculatory bulb protein III http://flybase.net/reports/FBgn0011695.html "FBgn0034960, FBgn0062902" protein_coding_gene "0045297=post-mating behavior, 0007552=metamorphosis, 0009615=response to virus" 0005576=extracellular region "phk-2, PebIII, PEB, Pherokine 2, PEBmeIII, BcDNA:RH74005, DmelCSP2, Phk-2, PEBmelIII, CG11390" IPR005055=Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG11390 16-Dec-15 2015_12 viable DRSC04638 E -0.185157191 -1.362083093 -1.301704825 2.018970131 0.464766036 0.605413067 FBgn0027374 RevIII-3y RevIII-3y http://flybase.net/reports/FBgn0027374.html gene 16-Dec-15 2015_12 FBgn0000379 cru cream underscored http://flybase.net/reports/FBgn0000379.html gene cr-u 16-Dec-15 2015_12 "eye color defective,recessive" "pigment cell,Malpighian tubule" FBgn0014172 fs(3)93Ca fs(3)93Ca http://flybase.net/reports/FBgn0014172.html gene unnamed 16-Dec-15 2015_12 wing FBgn0023143 Uba1 Ubiquitin activating enzyme 1 http://flybase.net/reports/FBgn0023143.html "FBgn0010538, FBgn0010605, FBgn0010688" protein_coding_gene "0019779=Atg8 activating enzyme activity, 0004839=ubiquitin activating enzyme activity" "0000209=protein polyubiquitination, 0040008=regulation of growth, 0006914=autophagy, 0016322=neuron remodeling, 0035096=larval midgut cell programmed cell death, 0046578=regulation of Ras protein signal transduction, 0008283=cell proliferation, 0019915=lipid storage, 0043067=regulation of programmed cell death, 0016567=protein ubiquitination, 0016319=mushroom body development" "0030425=dendrite, 0005886=plasma membrane" "uba1, l(2)03405, Uba 1, FBtr0088499, ubiquitin activating enzyme, UBA-1, E1 ligase, l(2)s3484, ubiquitin activating enzyme 1, 2/31, ubiquitin-activating enzyme (E1), l(2)05642, DmUba1, CG1782, Ubiquitin Activating Enzyme, uba-1, E1" "IPR018075=Ubiquitin-activating enzyme, E1, IPR016040=NAD(P)-binding domain, IPR018965=Ubiquitin-activating enzyme E1, C-terminal, IPR000594=THIF-type NAD/FAD binding fold, IPR019572=Ubiquitin-activating enzyme, catalytic cysteine domain, IPR000011=Ubiquitin/SUMO-activating enzyme E1, IPR018074=Ubiquitin-activating enzyme, E1, active site" CG1782 16-Dec-15 2015_12 ENSDARG00000037559(uba1) YKL210W(UBA1) WBGene00006699(uba-1) ENSXETG00000010202(UBA1) "ENSMUSG00000001924(Uba1),ENSMUSG00000071964,ENSMUSG00000069053(Ube1y1)" ENSG00000130985(UBA1) "neuroanatomy defective,somatic clone,lethal,recessive,visible,partially lethal - majority die,cell lethalcell lethal,heat sensitive,decreased cell death,increased cell death,increased cell number,cell non-autonomous,lethal - all die before end of pupal stage,some die during pupal stage" "adult mushroom body,somatic clone,macrochaeta,dendritic arborizing neuron,neuroblast,dendrite | somatic clone,mushroom body & axon | somatic clone,eye,eye disc,intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse,heat sensitive,eye-antennal disc,inter-ommatidial cell,retina,eye disc posterior to the morphogenetic furrow,cell non-autonomous,leg,proboscis,humeral disc" FBgn0015461 l(2)37CDf lethal (2) 37CDf http://flybase.net/reports/FBgn0015461.html gene l(2)E27 16-Dec-15 2015_12 "lethal,recessive" FBgn0002399 l(3)96Fc lethal (3) 96Fc http://flybase.net/reports/FBgn0002399.html gene "C3, l(3)C3" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001031 Fs(3)Boj Female sterile (3) Bojla http://flybase.net/reports/FBgn0001031.html gene "Fs(3)Sz5, Boj, Fs(3)Bojla" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0003049 pd purpleoid http://flybase.net/reports/FBgn0003049.html gene 16-Dec-15 2015_12 "visible,semidominant,eye color defective" pigment cell FBgn0051437 CG31437 http://flybase.net/reports/FBgn0051437.html protein_coding_gene IPR008160=Collagen triple helix repeat CG31437 16-Dec-15 2015_12 viable FBgn0022322 l(1)B23.2 lethal (1) B23.2 http://flybase.net/reports/FBgn0022322.html gene B23.2 16-Dec-15 2015_12 "lethal,recessive" FBgn0060391 l(3)S133801 lethal (3) S133801 http://flybase.net/reports/FBgn0060391.html gene 1338/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0034758 CG13510 http://flybase.net/reports/FBgn0034758.html protein_coding_gene 0009631=cold acclimation IPR006629=LPS-induced tumour necrosis factor alpha factor CG13510 16-Dec-15 2015_12 WBGene00013604(Y87G2A.18) viable FBgn0038148 CG14377 http://flybase.net/reports/FBgn0038148.html protein_coding_gene CG14377 16-Dec-15 2015_12 viable FBgn0003988 Vno Vein off http://flybase.net/reports/FBgn0003988.html gene 16-Dec-15 2015_12 "visible,dominant" "wing vein L2,wing vein L4,wing vein L5,wing vein,wing vein L3,wing margin bristle" FBgn0000354 cp clipped http://flybase.net/reports/FBgn0000354.html gene 0007476=imaginal disc-derived wing morphogenesis "Cp, E(nd)88" 16-Dec-15 2015_12 "visible,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,wing margin bristle" FBgn0044080 E(rst)H54 E(rst)H54 http://flybase.net/reports/FBgn0044080.html gene 0001745=compound eye morphogenesis H54 16-Dec-15 2015_12 viable eye FBgn0034368 CG5482 http://flybase.net/reports/FBgn0034368.html protein_coding_gene "0005528=FK506 binding, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0018208=peptidyl-proline modification, 0006457=protein folding" "0012505=endomembrane system, 0016020=membrane" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain" CG5482 16-Dec-15 2015_12 "ENSDARG00000056490,ENSDARG00000001734(LOC798767),ENSDARG00000001976(si:ch211-13k12.1)" "ENSXETG00000023205(FKBP8),ENSXETG00000004647()" ENSMUSG00000019428(Fkbp8) ENSG00000105701(FKBP8) lethal FBgn0039687 CG7593 http://flybase.net/reports/FBgn0039687.html protein_coding_gene 0008080=N-acetyltransferase activity 0006909=phagocytosis Ubiquinol-cytochrome C reductase complex 11 kDa protein "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG7593 16-Dec-15 2015_12 ENSDARG00000024109(naa40) WBGene00021392(Y38A10A.7) ENSXETG00000002713(NAA40) ENSMUSG00000024764(Naa40) ENSG00000110583(NAA40) "viable,fertile" FBgn0029914 CG4558 http://flybase.net/reports/FBgn0029914.html protein_coding_gene CG4558 16-Dec-15 2015_12 FBgn0266657 CR45164 http://flybase.net/reports/FBgn0266657.html non_protein_coding_gene CR45164 16-Dec-15 2015_12 FBgn0065608 l(2)SH0842 lethal (2) SH0842 http://flybase.net/reports/FBgn0065608.html gene l(2)SH2 0842 16-Dec-15 2015_12 "lethal,recessive" FBgn0038799 MFS9 Major Facilitator Superfamily Transporter 9 http://flybase.net/reports/FBgn0038799.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane CG4288 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG4288 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" WBGene00022647(ZK54.1) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267505 pre-rRNA:CR45845 ribosomal RNA primary transcript:CR45845 http://flybase.net/reports/FBgn0267505.html rRNA_gene CR45845 CR45845 16-Dec-15 2015_12 FBgn0054027 CG34027 http://flybase.net/reports/FBgn0054027.html FBgn0082878 protein_coding_gene "unnamed, BP1028" CG34027 16-Dec-15 2015_12 FBgn0039967 CG17925 http://flybase.net/reports/FBgn0039967.html FBan0017925 protein_coding_gene 0003779=actin binding 16-Dec-15 2015_12 "ENSDARG00000028548,ENSDARG00000005814(LOC100333629)" "WBGene00002186(kel-10),WBGene00018563(F47D12.7)" ENSXETG00000003818(KLHL10) ENSMUSG00000001558(Klhl10) ENSG00000161594(KLHL10) FBgn0265383 CR44324 http://flybase.net/reports/FBgn0265383.html non_protein_coding_gene CR44324 16-Dec-15 2015_12 FBgn0003219 rdm reduced macros http://flybase.net/reports/FBgn0003219.html gene 16-Dec-15 2015_12 "visible,male fertile,viable,male,poor" "macrochaeta,wing,eye" FBgn0085171 CycA-PRE Cyclin A Polycomb group response element http://flybase.net/reports/FBgn0085171.html regulatory_region 16-Dec-15 2015_12 FBgn0001944 l(2)26Ae lethal (2) 26Ae http://flybase.net/reports/FBgn0001944.html gene l(2)gdh-6 16-Dec-15 2015_12 "lethal,recessive" FBgn0053734 snmRNA:430:CR33734 snmRNA:430:CR33734 http://flybase.net/reports/FBgn0053734.html non_protein_coding_gene CR33734 CR33734 16-Dec-15 2015_12 FBgn0065298 l(2)SH1995 lethal (2) SH1995 http://flybase.net/reports/FBgn0065298.html gene l(2)SH2 1995 16-Dec-15 2015_12 "lethal,recessive" FBgn0060732 l(3)S067210b lethal (3) S067210b http://flybase.net/reports/FBgn0060732.html gene 0672/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0019855 anon-IX anon-IX http://flybase.net/reports/FBgn0019855.html gene IX 16-Dec-15 2015_12 FBgn0033766 CG8771 http://flybase.net/reports/FBgn0033766.html protein_coding_gene 0017056=structural constituent of nuclear pore 0006999=nuclear pore organization 0044611=nuclear pore inner ring Nup188 IPR018864=Nucleoporin Nup188 CG8771 16-Dec-15 2015_12 ENSDARG00000030022(nup188) ENSXETG00000012903() ENSMUSG00000052533(Nup188) ENSG00000095319(NUP188) "smell perception defective,female limited,viable" DRSC29937 K 0.288062629 -0.40709298 0.135832807 0.152286318 0.197661336 1.581169659 FBgn0028895 CG17328 http://flybase.net/reports/FBgn0028895.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "BG:DS02740.8, DS02740.8" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG17328 16-Dec-15 2015_12 "WBGene00003087(lsy-2),WBGene00009937(lsl-1)" viable FBgn0024987 ssx sister-of-Sex-lethal http://flybase.net/reports/FBgn0024987.html FBgn0027771 protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding, 0000166=nucleotide binding" 0042742=defense response to bacterium "EG:132E8.1, anon-EST:Posey102, CG3056, cg3056" "IPR000504=RNA recognition motif domain, IPR002343=Paraneoplastic encephalomyelitis antigen, IPR012677=Nucleotide-binding alpha-beta plait domain" CG3056 16-Dec-15 2015_12 "YHR015W(MIP6),YFR023W(PES4)" "viable,male fertile,female fertile,fertile" DRSC18492 I 1.645503872 -1.930822612 0.323124438 -1.309049388 -0.236162532 0.172936914 FBgn0040833 CG7498 http://flybase.net/reports/FBgn0040833.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0065131 l(3)SH131 lethal (3) SH131 http://flybase.net/reports/FBgn0065131.html gene l(2)SH3 131 16-Dec-15 2015_12 "lethal,recessive" FBgn0033890 Ctf4 http://flybase.net/reports/FBgn0033890.html FBgn0044696 protein_coding_gene 0003677=DNA binding "0035185=preblastoderm mitotic cell cycle, 0000278=mitotic cell cycle, 0042023=DNA endoreduplication" "CG13350, anon-WO0140519.180" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR022100=Minichromosome loss protein Mcl1, middle region" CG13350 16-Dec-15 2015_12 WBGene00008921(F17C11.10) ENSXETG00000012210(WDHD1) ENSMUSG00000037572(Wdhd1) ENSG00000198554(WDHD1) "mitotic cell cycle defective,endomitotic cell cycle defective,chemical sensitive,lethal,some die during immature adult stage,recessive,maternal effect,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "polytene chromosomeAct.PU,mesothoracic tergum" FBgn0264390 CR43838 http://flybase.net/reports/FBgn0264390.html non_protein_coding_gene lincRNA.1030 CR43838 16-Dec-15 2015_12 FBgn0025833 CG8910 http://flybase.net/reports/FBgn0025833.html FBgn0044651 protein_coding_gene 0008270=zinc ion binding "EG:EG0003.1, anon-WO0140519.220" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG8910 16-Dec-15 2015_12 "viable,fertile" FBgn0030710 CG8924 http://flybase.net/reports/FBgn0030710.html protein_coding_gene 0003677=DNA binding "IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR007889=DNA binding HTH domain, Psq-type" CG8924 16-Dec-15 2015_12 viable FBgn0052475 mthl8 methuselah-like 8 http://flybase.net/reports/FBgn0052475.html "FBgn0035095, FBgn0035096, FBgn0046589, FBgn0046590" protein_coding_gene 0004930=G-protein coupled receptor activity "0042594=response to starvation, 0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan" 0016021=integral component of membrane "CG13406, anon-WO0170980.146, Methuselah-like 8, Mth-8, CG11869, mthl-8, Mth-like 8, anon-WO0170980.145, CG32475, mth-like 8" "IPR023311=Methuselah ectodomain, domain 2, IPR010596=Methuselah, N-terminal domain" CG32475 16-Dec-15 2015_12 viable FBgn0034670 CG13488 http://flybase.net/reports/FBgn0034670.html protein_coding_gene CG13488 16-Dec-15 2015_12 viable FBgn0015949 hrg hiiragi http://flybase.net/reports/FBgn0015949.html "FBgn0022078, FBgn0034465, FBgn0040293" protein_coding_gene "0003723=RNA binding, 0004652=polynucleotide adenylyltransferase activity" 0006378=mRNA polyadenylation 0005634=nucleus "poly (A) polymerase, poly(A) polymerase, l(2)k07619, CG9854, PAP, Pap, l(2)07619, Poly(A) polymerase" "IPR011068=Nucleotidyltransferase, class I, C-terminal-like, IPR007010=Poly(A) polymerase, RNA-binding domain, IPR002934=Polymerase, nucleotidyl transferase domain, IPR007012=Poly(A) polymerase, central domain, IPR014492=Poly(A) polymerase" CG9854 16-Dec-15 2015_12 "ENSDARG00000012141(papolg),ENSDARG00000009585(papolb)" YKR002W(PAP1) "WBGene00012528(pap-1),WBGene00009658(F43G6.5),WBGene00011791(T15H9.6)" "ENSXETG00000002208(papolg),ENSXETG00000013949(papola)" "ENSMUSG00000020273(Papolg),ENSMUSG00000021111(Papola),ENSMUSG00000074817(Papolb)" "ENSG00000090060(PAPOLA),ENSG00000218823(PAPOLB),ENSG00000115421(PAPOLG)" "lethal,recessive,viable,fertile,lethal - all die before end of larval stage,partially,some die during larval stage,visible,wild-type,cell lethal,germline clone" "crystal cell,plasmatocyte,wing,dorsal bridge" FBgn0083306 E(smoDN)1496 Enhancer of smoDN 1496 http://flybase.net/reports/FBgn0083306.html gene 16-Dec-15 2015_12 FBgn0065417 l(2)SH1535 lethal (2) SH1535 http://flybase.net/reports/FBgn0065417.html gene l(2)SH2 1535 16-Dec-15 2015_12 "lethal,recessive" FBgn0039332 alrm astrocytic leucine-rich repeat molecule http://flybase.net/reports/FBgn0039332.html protein_coding_gene "CT37074, alrm, CG11910, astrocytic leucine-rich repeat molecule" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG11910 16-Dec-15 2015_12 ENSMUSG00000070056(Mfhas1) viable FBgn0025835 CG17707 http://flybase.net/reports/FBgn0025835.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" EG:23E12.3 "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG17707 16-Dec-15 2015_12 WBGene00003813(nrf-6) ENSMUSG00000046610(5330437I02Rik) viable FBgn0005019 dkb dark bubbly http://flybase.net/reports/FBgn0005019.html gene 16-Dec-15 2015_12 "visible,body color defective" adult thorax & cuticle FBgn0259296 EP-24 http://flybase.net/reports/FBgn0259296.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0039198 CG5768 http://flybase.net/reports/FBgn0039198.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG5768 16-Dec-15 2015_12 "viable,fertile" FBgn0013441 fop fop http://flybase.net/reports/FBgn0013441.html gene 16-Dec-15 2015_12 FBgn0016839 l(1)MZ8 lethal (1) MZ8 http://flybase.net/reports/FBgn0016839.html gene M8 16-Dec-15 2015_12 "lethal,recessive" FBgn0027979 l(3)S137908 lethal (3) S137908 http://flybase.net/reports/FBgn0027979.html gene 1379/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050350 CG30350 http://flybase.net/reports/FBgn0050350.html FBgn0033334 protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0006457=protein folding, 0000413=protein peptidyl-prolyl isomerization" CG8278 "IPR029488=KIAA1430 homologue, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR029000=Cyclophilin-like domain" CG30350 16-Dec-15 2015_12 FBgn0028196 l(3)S022231b lethal (3) S022231b http://flybase.net/reports/FBgn0028196.html gene "l(3)S022231, 0222/31" 16-Dec-15 2015_12 "lethal,recessive" FBgn0047306 CR32314 http://flybase.net/reports/FBgn0047306.html FBgn0052314 non_protein_coding_gene BcDNA:GH25089 16-Dec-15 2015_12 FBgn0038944 CG5388 http://flybase.net/reports/FBgn0038944.html protein_coding_gene CG5388 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0016711 Reg-16 Rhythmically expressed gene 16 http://flybase.net/reports/FBgn0016711.html gene "Dreg-16, Drosophila Rhythmically expressed gene 16" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " adult head

FBgn0267078 CR45522 http://flybase.net/reports/FBgn0267078.html non_protein_coding_gene CR45522 16-Dec-15 2015_12 FBgn0262030 CG42841 http://flybase.net/reports/FBgn0262030.html protein_coding_gene CG42841 16-Dec-15 2015_12 FBgn0002410 l(3)99Ea lethal (3) 99Ea http://flybase.net/reports/FBgn0002410.html gene 16-Dec-15 2015_12 lethal FBgn0022713 2Ab17 2Ab17 http://flybase.net/reports/FBgn0022713.html gene p2Ab17 16-Dec-15 2015_12 FBgn0053096 CG33096 http://flybase.net/reports/FBgn0053096.html FBgn0039275 protein_coding_gene 0005886=plasma membrane CG11935 "IPR029059=Alpha/beta hydrolase fold-5, IPR029058=Alpha/Beta hydrolase fold" CG33096 16-Dec-15 2015_12 "ENSDARG00000035571(zgc:100937),ENSDARG00000043084(si:rp71-61h23.3),ENSDARG00000058452(zgc:55468)" WBGene00010561(K04G2.2) "ENSXETG00000027472(BC076960.1),ENSXETG00000008147(TEgg070o01.1),ENSXETG00000027627(BC074709.1)" "ENSMUSG00000047368(Fam108b),ENSMUSG00000003346(Fam108a),ENSMUSG00000038459(Fam108c)" "ENSG00000107362(FAM108B1),ENSG00000136379(FAM108C1),ENSG00000203835,ENSG00000198658,ENSG00000129968(FAM108A1),ENSG00000182502" viable FBgn0062532 ff6 ff6 http://flybase.net/reports/FBgn0062532.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male,mitotic cell cycle defective" "spermatid,meiotic cell cycle | male,centriole,spindle" FBgn0005059 fs(2)OW105 female sterile (2) OW105 http://flybase.net/reports/FBgn0005059.html gene 16-Dec-15 2015_12 FBgn0033426 CG1814 http://flybase.net/reports/FBgn0033426.html protein_coding_gene "45551045, 45550393" "IPR023214=HAD-like domain, IPR008380=HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase, IPR016695=Purine 5'-nucleotidase" CG1814 16-Dec-15 2015_12 "ENSDARG00000062949(nt5dc3),ENSDARG00000059646(nt5dc2)" "ENSXETG00000023942(),ENSXETG00000013678(NT5DC2),ENSXETG00000005357(NT5DC3)" "ENSMUSG00000054027(Nt5dc3),ENSMUSG00000071547(Nt5dc2)" "ENSG00000111696(NT5DC3),ENSG00000168268(NT5DC2)" viable DRSC06711 IE 2.760233289 1.255609314 1.976211852 -1.520704885 -0.097523954 0.302923685 FBgn0050351 CG30351 http://flybase.net/reports/FBgn0050351.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262853 CR43217 http://flybase.net/reports/FBgn0262853.html pseudogene_attribute "noncoding_23161, noncoding_23159" CR43217 16-Dec-15 2015_12 FBgn0058190 CG40190 http://flybase.net/reports/FBgn0058190.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263452 CR43475 http://flybase.net/reports/FBgn0263452.html non_protein_coding_gene CR43475 16-Dec-15 2015_12 FBgn0037478 CG2656 http://flybase.net/reports/FBgn0037478.html FBgn0045110 protein_coding_gene 0017076=purine nucleotide binding "0022008=neurogenesis, 0048812=neuron projection morphogenesis" NEST:bs33f03 "IPR004130=GPN-loop GTPase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR030228=GPN-loop GTPase 3" CG2656 16-Dec-15 2015_12 "ENSDARG00000069525(gpn3),ENSDARG00000067505" YLR243W() WBGene00013550(Y75B8A.14) ENSXETG00000020939(TEgg091j20.1) ENSMUSG00000029464(Gpn3) ENSG00000111231(GPN3) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0262366 CG43064 http://flybase.net/reports/FBgn0262366.html protein_coding_gene MIP22993 CG43064 16-Dec-15 2015_12 FBgn0042156 CG18833 http://flybase.net/reports/FBgn0042156.html protein_coding_gene 16-Dec-15 2015_12 FBgn0058394 CG40394 http://flybase.net/reports/FBgn0058394.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004677 e(faswb) enhancer of facet-strawberry http://flybase.net/reports/FBgn0004677.html gene "fa[swb-h], facet-strawberry-hairy, e(fa[swb])fa[swb]" 16-Dec-15 2015_12 FBgn0000672 fliG flightless G http://flybase.net/reports/FBgn0000672.html gene "0008586=imaginal disc-derived wing vein morphogenesis, 0007629=flight behavior" 16-Dec-15 2015_12 "flightless,visible,lethal,cold sensitive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein" FBgn0002114 l(2)bl lethal (2) bluter http://flybase.net/reports/FBgn0002114.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0034804 CG3831 http://flybase.net/reports/FBgn0034804.html protein_coding_gene CG3831 16-Dec-15 2015_12 viable FBgn0034914 CG5554 http://flybase.net/reports/FBgn0034914.html protein_coding_gene 0003756=protein disulfide isomerase activity 0045454=cell redox homeostasis "0012505=endomembrane system, 0016021=integral component of membrane" "IPR017937=Thioredoxin, conserved site, IPR012336=Thioredoxin-like fold, IPR013766=Thioredoxin domain" CG5554 16-Dec-15 2015_12 ENSDARG00000019487(tmx1) WBGene00001073(dpy-11) ENSXETG00000016489(TEgg123p24.1) ENSMUSG00000034723(Tmx4) ENSG00000139921(TMX1) viable FBgn0033089 CG17266 http://flybase.net/reports/FBgn0033089.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0000413=protein peptidyl-prolyl isomerization, 0000398=mRNA splicing, via spliceosome, 0006457=protein folding" "0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0005681=spliceosomal complex" "IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain" CG17266 16-Dec-15 2015_12 ENSDARG00000041530(ppih) WBGene00000887(cyn-11) ENSXETG00000013439(ppih) ENSMUSG00000060288(Ppih) ENSG00000171960(PPIH) viable FBgn0052757 CG32757 http://flybase.net/reports/FBgn0052757.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028583 lcs la costa http://flybase.net/reports/FBgn0028583.html protein_coding_gene "leader sequence, collagen-related repetitive motif and a serine/threonine-rich motif, CG12794" CG12794 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0082919 snoRNA:Or-CD4 http://flybase.net/reports/FBgn0082919.html snoRNA_gene "orphan CD4, snoRNA:Or-cd4, DmOr_cd4, DmOr_cd4 snoRNA, CR34542" CR34542 16-Dec-15 2015_12 FBgn0052494 CG32494 http://flybase.net/reports/FBgn0052494.html protein_coding_gene 16-Dec-15 2015_12 DRSC19222 I -0.568608245 -2.223938461 0.045729701 -0.085418759 -0.539987817 -1.409095899 FBgn0067767 hard-boiled hard boiled http://flybase.net/reports/FBgn0067767.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0259721 CG42375 http://flybase.net/reports/FBgn0259721.html FBgn0038182 protein_coding_gene "Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_uORF, CG9288" IPR013892=Cytochrome c oxidase biogenesis protein Cmc1-like CG42375 16-Dec-15 2015_12 ENSDARG00000043635(si:busm1-241h12.4) WBGene00016452(C35D10.17) ENSMUSG00000014633(2310061C15Rik) ENSG00000103121(C16orf61) FBgn0019768 l(1)54 lethal (1) 54 http://flybase.net/reports/FBgn0019768.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041717 snRNA:U6atac:29B U6atac snRNA at 29B http://flybase.net/reports/FBgn0041717.html FBgn0022254 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005691=U6atac snRNP "U6atac, CR32989, l(2)k01105, U6atac:29B, U6atac-29B" CR32989 16-Dec-15 2015_12 "lethal,recessive" "crystal cell,imaginal disc" FBgn0085386 CG34357 http://flybase.net/reports/FBgn0085386.html "FBan0009783, FBan0014652, FBgn0037258, FBgn0037259, FBgn0037257, FBgn0084028, FBgn0037256" protein_coding_gene "0004872=receptor activity, 0005524=ATP binding, 0004383=guanylate cyclase activity, 0004672=protein kinase activity" "0019934=cGMP-mediated signaling, 0006182=cGMP biosynthetic process, 0006468=protein phosphorylation" 0005887=integral component of plasma membrane "CG41467, GYC, CG12584, CG14652, CG12585, CG9783" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG34357 16-Dec-15 2015_12 "ENSDARG00000026820(gc3),ENSDARG00000025504(gucy2f),ENSDARG00000018329(gc2)" viable DRSC28043 K -0.144182816 0.347424776 -0.003741696 0.20928351 -1.79188803 0.172604952 FBgn0020340 anon-5Cb anon-5Cb http://flybase.net/reports/FBgn0020340.html gene unnamed 16-Dec-15 2015_12 FBgn0262770 Su(E1)-D http://flybase.net/reports/FBgn0262770.html gene 16-Dec-15 2015_12 FBgn0005761 l(1)TK407 lethal (1) TK407 http://flybase.net/reports/FBgn0005761.html gene l407 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0266780 CR45245 http://flybase.net/reports/FBgn0266780.html non_protein_coding_gene CR45245 16-Dec-15 2015_12 FBgn0060853 l(3)S048412a lethal (3) S048412a http://flybase.net/reports/FBgn0060853.html gene 0484/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0266151 CR44857 http://flybase.net/reports/FBgn0266151.html non_protein_coding_gene CR44857 16-Dec-15 2015_12 FBgn0069418 JJF136 JJF136 http://flybase.net/reports/FBgn0069418.html gene 16-Dec-15 2015_12 stress response defective FBgn0264647 impatent impatent http://flybase.net/reports/FBgn0264647.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0002321 l(3)85Ee lethal (3) 85Ee http://flybase.net/reports/FBgn0002321.html gene 16-Dec-15 2015_12 lethal FBgn0030071 CG12661 http://flybase.net/reports/FBgn0030071.html protein_coding_gene "IPR008560=Protein of unknown function DUF842, eukaryotic" CG12661 16-Dec-15 2015_12 ENSDARG00000040148(fam136a) viable FBgn0267962 CR46242 http://flybase.net/reports/FBgn0267962.html non_protein_coding_gene lincRNA.992 CR46242 16-Dec-15 2015_12 FBgn0064210 UY2517 UY2517 http://flybase.net/reports/FBgn0064210.html gene 16-Dec-15 2015_12 chemical resistant FBgn0005690 Nc34CD Neural conserved at 34CD http://flybase.net/reports/FBgn0005690.html gene NC34CD 16-Dec-15 2015_12 FBgn0267229 CR45669 http://flybase.net/reports/FBgn0267229.html non_protein_coding_gene CG45669 CR45669 16-Dec-15 2015_12 FBgn0052187 CG32187 http://flybase.net/reports/FBgn0052187.html FBgn0036755 protein_coding_gene "DPLG2, PIF-like gene 2, CG5584" IPR027806=Harbinger transposase-derived nuclease domain CG32187 16-Dec-15 2015_12 "ENSDARG00000053799,ENSDARG00000054089,ENSDARG00000057526" "partially lethal - majority die,some die during pupal stage" FBgn0005735 l(1)TK222 lethal (1) TK222 http://flybase.net/reports/FBgn0005735.html gene l222 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0265588 CR44415 http://flybase.net/reports/FBgn0265588.html non_protein_coding_gene CR44415 16-Dec-15 2015_12 FBgn0058001 CG40001 http://flybase.net/reports/FBgn0058001.html FBan0040001 protein_coding_gene 16-Dec-15 2015_12 FBgn0015252 M(1)15DEF Minute (1) 15DEF http://flybase.net/reports/FBgn0015252.html gene 16-Dec-15 2015_12 "lethal,recessive,Minute,dominant" FBgn0265979 CR44758 http://flybase.net/reports/FBgn0265979.html non_protein_coding_gene lincRNA.373 CR44758 16-Dec-15 2015_12 FBgn0033453 CG1667 http://flybase.net/reports/FBgn0033453.html protein_coding_gene "0002218=activation of innate immune response, 0032481=positive regulation of type I interferon production" IPR029158=Stimulator of interferon genes protein CG1667 16-Dec-15 2015_12 ENSXETG00000016088(TMEM173) ENSMUSG00000024349(Tmem173) "partially lethal - majority die,viable" DRSC06615 IE 0.855693288 1.570866329 0.699681934 1.798709251 -0.09406758 -0.464888396 FBgn0085568 CG41240 http://flybase.net/reports/FBgn0085568.html FBan0041240 protein_coding_gene 16-Dec-15 2015_12 FBgn0083006 snoRNA:ë¬28S-1153 snoRNA:ë¬28S-1153 http://flybase.net/reports/FBgn0083006.html snoRNA_gene "psi28s-1153, Psi 28S-1153, chr2R:9073472..9073780, CR34531" CR34531 16-Dec-15 2015_12 FBgn0261856 CR42785 http://flybase.net/reports/FBgn0261856.html pseudogene_attribute noncoding_4773 CR42785 16-Dec-15 2015_12 FBgn0032873 CG2614 http://flybase.net/reports/FBgn0032873.html protein_coding_gene 0008168=methyltransferase activity 0008152=metabolic process 38D.29 "IPR013216=Methyltransferase type 11, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG2614 16-Dec-15 2015_12 ENSDARG00000010905(LOC100330026) WBGene00015282(C01B10.8) ENSXETG00000010438(TEgg102o03.1) ENSMUSG00000026694(Mettl13) ENSG00000010165(METTL13) viable FBgn0263049 let-7-C let-7-Complex http://flybase.net/reports/FBgn0263049.html non_protein_coding_gene "0016319=mushroom body development, 0071390=cellular response to ecdysone, 0010629=negative regulation of gene expression" "let-7-C, let-7-Complex, pri-let-7-C, CR43344" CR43344 16-Dec-15 2015_12 "neuroanatomy defective,somatic clone,dominant" "mushroom body,somatic clone,adult mushroom body alpha'-lobe,adult mushroom body beta'-lobe,adult mushroom body gamma-lobe" FBgn0065683 l(2)SH0661 lethal (2) SH0661 http://flybase.net/reports/FBgn0065683.html gene l(2)SH2 0661 16-Dec-15 2015_12 "lethal,recessive" FBgn0002102 l(2)57Dc lethal (2) 57Dc http://flybase.net/reports/FBgn0002102.html gene l(2)57Ed 16-Dec-15 2015_12 "lethal,recessive" FBgn0266857 CR45318 http://flybase.net/reports/FBgn0266857.html non_protein_coding_gene CR45318 16-Dec-15 2015_12 FBgn0003478 splw splay wing http://flybase.net/reports/FBgn0003478.html gene 16-Dec-15 2015_12 "male sterile,recessive,viable,male,reduced,visible" "wing,eye" FBgn0004479 l(1)air3 lethal aberrant immune response 3 http://flybase.net/reports/FBgn0004479.html gene 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0267776 CR46107 http://flybase.net/reports/FBgn0267776.html non_protein_coding_gene CR46107 16-Dec-15 2015_12 FBgn0020224 Cbl Cbl proto-oncogene ortholog http://flybase.net/reports/FBgn0020224.html "FBgn0035894, FBgn0041253, FBgn0061761" protein_coding_gene "0008270=zinc ion binding, 0030971=receptor tyrosine kinase binding, 0005515=protein binding, 0005509=calcium ion binding, 0004871=signal transducer activity, 0016874=ligase activity, 0001784=phosphotyrosine binding, 0004842=ubiquitin-protein transferase activity" "0009950=dorsal/ventral axis specification, 0006508=proteolysis, 0006109=regulation of carbohydrate metabolic process, 0007465=R7 cell fate commitment, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0007298=border follicle cell migration, 0007173=epidermal growth factor receptor signaling pathway, 0048134=germ-line cyst formation, 0007476=imaginal disc-derived wing morphogenesis, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0001754=eye photoreceptor cell differentiation, 0010941=regulation of cell death, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0032353=negative regulation of hormone biosynthetic process, 0006897=endocytosis, 0042127=regulation of cell proliferation, 0007175=negative regulation of epidermal growth factor-activated receptor activity" "0005938=cell cortex, 0005737=cytoplasm, 0005634=nucleus" "Dv-cbl, D-cblLONG, Dv-Cbl, cable, Dcbl, D-cbl, D-Cbl L, anon-WO0118547.68, unnamed, CG7043, DCbl, d-cbl, v-Cbl, Cbl, cbl, D-cblL, CG7037, F165, CBL, D-cblS, D-Cbl, dCbl, D-cblSHORT" "IPR024162=Adaptor protein Cbl, IPR014741=Adaptor protein Cbl, EF hand-like, IPR009060=UBA-like, IPR001841=Zinc finger, RING-type, IPR024159=Adaptor protein Cbl, PTB domain, IPR003153=Adaptor protein Cbl, N-terminal helical, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000980=SH2 domain, IPR017907=Zinc finger, RING-type, conserved site, IPR015940=Ubiquitin-associated domain, IPR011992=EF-hand domain pair, IPR014742=Adaptor protein Cbl, SH2-like" CG7037 16-Dec-15 2015_12 ENSDARG00000009958(cbl) WBGene00004829(sli-1) "ENSXETG00000016127(CBLB),ENSXETG00000021588(cbl)" "ENSMUSG00000034342(Cbl),ENSMUSG00000022637(Cblb)" "ENSG00000114423(CBLB),ENSG00000110395(CBL)" " embryonic stage | stage 1-3 , larval stage | third instar , embryonic stage | early , embryonic stage | blastoderm " " organism

, imaginal disc

" " embryonic stage | stage 15 , embryonic stage | blastoderm , embryonic stage | early " " pharyngeal muscle

, embryonic/larval hindgut

, Malpighian tubule

" "viable,fertile,partially lethal - majority die,male limited,developmental rate defective,starvation stress response defective,short lived,lethal - all die before end of P-stage,some die during P-stage,lethal,recessive,visible,dominant,neuroanatomy defective,large body,oxidative stress response defective,decreased cell death,somatic clone" "egg,chorion,dorsal appendage,wing vein L4,wing vein L5,anterior crossvein,eye,ommatidium,adult abdominal segment,tergite,chorion | maternal effect, with CblF165,maternal effect,wing vein,ectopic,wing,neuron,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,photoreceptor cell,photoreceptor cell R7,somatic clone,chorion | maternal effect | somatic clone,embryo,denticle belt,germline clone,rescuable maternal effect,border follicle cell,chorion | maternal effect, with CblL.Hsp83,primary pigment cell,secondary pigment cell,tertiary pigment cell,abdominal ventral denticle belt" DRSC28169 EK -0.909443407 0.087494379 0.066135572 2.158431619 -1.52115144 -2.508510141 FBgn0046687 Tre1 Trapped in endoderm 1 http://flybase.net/reports/FBgn0046687.html "FBgn0026580, FBgn0029786, FBgn0046493, FBgn0046572, FBgn0046580, FBgn0064143" protein_coding_gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0035234=ectopic germ cell programmed cell death, 0007281=germ cell development, 0007280=pole cell migration, 0008354=germ cell migration" "0005938=cell cortex, 0016021=integral component of membrane" "anon-WO0170980.17, CG3171, sctt, Tre, trapped in endoderm-1, tre-1, BEST:LD12308, Tre-1, tre1, scattershot, LD12308, trapped in endoderm 1, anon-WO0170980.16, G protein coupled receptor, Trapped in endoderm 1, anon-WO0170981.1" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG3171 16-Dec-15 2015_12 "ENSDARG00000069225,ENSDARG00000069221,ENSDARG00000055852(LOC565718),ENSDARG00000037545(mtnr1aa),ENSDARG00000035609(mtnr1c),ENSDARG00000012057" ENSXETG00000021274(GPR84) ENSMUSG00000063234(Gpr84) ENSG00000139572(GPR84) "chemosensitive behavior defective,viable,fertile,neuroanatomy defective,visible,partially lethal - majority die,lethal,wild-type,female sterile,recessive,rescuable maternal effect,male sterile,maternal effect,short lived,male,starvation stress response defective,female,heat stress response defective" "embryonic neuroblast,presumptive embryonic/larval central nervous system,macrochaeta,eye,wing,germline cell,ectopic,maternal effect,rescuable maternal effect,non-rescuable maternal effect,gonad" FBgn0026164 tRNA:K5:84ABb tRNA:K5:84ABb http://flybase.net/reports/FBgn0026164.html "FBgn0003793, FBgn0011901, FBgn0051489, FBgn0060172" tRNA_gene 0033443=AAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31489, tRNA:K:TTT:AE002699-e, chr3R.trna3-LysTTT, AE002699.trna10-LysTTT, lys5:84ABb, tRNA:K5, BG:DS00276.2" CR31489 16-Dec-15 2015_12 FBgn0039870 CG1896 http://flybase.net/reports/FBgn0039870.html protein_coding_gene CG1896 16-Dec-15 2015_12 viable FBgn0051374 sals sarcomere length short http://flybase.net/reports/FBgn0051374.html "FBgn0037904, FBgn0037905" protein_coding_gene 0051015=actin filament binding "0030838=positive regulation of actin filament polymerization, 0060297=regulation of sarcomere organization" 0005865=striated muscle thin filament "sarcomere length short, CG31374, CG14703, CG6771, sals" IPR003124=WH2 domain CG31374 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,locomotor behavior defective,recessive" "sarcomere,myofibril,striated muscle thin filament" FBgn0083297 E(smoDN)1857 Enhancer of smoDN 1857 http://flybase.net/reports/FBgn0083297.html gene 16-Dec-15 2015_12 FBgn0001164 gv grooved http://flybase.net/reports/FBgn0001164.html gene "gs, gespleten" 16-Dec-15 2015_12 "viable,fertile,visible,lethal,recessive" "adult thorax,eye,mesothoracic bristle,adult thorax & trichome" FBgn0261586 CR42696 http://flybase.net/reports/FBgn0261586.html non_protein_coding_gene CG42696 CR42696 16-Dec-15 2015_12 FBgn0001592 l(1)carot9 lethal (1) carot9 http://flybase.net/reports/FBgn0001592.html gene 16-Dec-15 2015_12 lethal FBgn0003573 su(pr) suppressor of purple http://flybase.net/reports/FBgn0003573.html gene 16-Dec-15 2015_12 "viable,fertile" FBgn0030408 CG11085 http://flybase.net/reports/FBgn0030408.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR020479=Homeodomain, metazoa" CG11085 16-Dec-15 2015_12 viable DRSC22832 K -0.683388551 0.826231749 -0.687523383 0.421765126 -1.534277835 -0.213804046 FBgn0023113 anon-10Au anon-10Au http://flybase.net/reports/FBgn0023113.html gene 14 16-Dec-15 2015_12 FBgn0259195 CG42299 http://flybase.net/reports/FBgn0259195.html "FBan0032584, FBgn0052584" protein_coding_gene 0019789=SUMO transferase activity 0000724=double-strand break repair via homologous recombination 0030915=Smc5-Smc6 complex "CG32584, CG15644, CG18620" IPR026846=E3 SUMO-protein ligase Nse2 (Mms21) CG42299 16-Dec-15 2015_12 WBGene00022881(ZK1248.11) ENSMUSG00000059586(Nsmce2) ENSG00000156831(NSMCE2) viable FBgn0042126 CG18788 http://flybase.net/reports/FBgn0042126.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG18788 16-Dec-15 2015_12 "YOR378W(),YML116W(ATR1),YMR279C()" viable FBgn0065766 l(2)SH0473 lethal (2) SH0473 http://flybase.net/reports/FBgn0065766.html gene l(2)SH2 0473 16-Dec-15 2015_12 "lethal,recessive" FBgn0032626 CG12620 http://flybase.net/reports/FBgn0032626.html protein_coding_gene 0004864=protein phosphatase inhibitor activity "0009966=regulation of signal transduction, 0043666=regulation of phosphoprotein phosphatase activity" 0000164=protein phosphatase type 1 complex IPR007062=Protein phosphatase inhibitor 2 (IPP-2) CG12620 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0039568 CG4815 http://flybase.net/reports/FBgn0039568.html protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space SP189 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG4815 16-Dec-15 2015_12 viable FBgn0051217 modSP modular serine protease http://flybase.net/reports/FBgn0051217.html "FBgn0013291, FBgn0015294" protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0045087=innate immune response" "Dm-SP, Ser89E, Serine protease like 89E, predicted gene X, SP53, Serine protease-like, W, LDL, CG17557, X, predicted gene W, SP172, CG10100, CT28389, ModSP, low density lipoprotein receptor-like 'a' repeats, Ldlr, CG31217" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR000436=Sushi/SCR/CCP domain" CG31217 16-Dec-15 2015_12 ENSXETG00000009837(CORIN) "lethal,immune response defective,viable,fertile" FBgn0060955 l(3)S034602b lethal (3) S034602b http://flybase.net/reports/FBgn0060955.html gene 0346/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003107 PL(3)w-S Polygenic locus weight S http://flybase.net/reports/FBgn0003107.html gene "IIIw, PL(3)w[S]" 16-Dec-15 2015_12 FBgn0040086 p147 p147 http://flybase.net/reports/FBgn0040086.html gene "0007319=negative regulation of oskar mRNA translation, 0045451=pole plasm oskar mRNA localization" 16-Dec-15 2015_12 FBgn0264889 CR44080 http://flybase.net/reports/FBgn0264889.html non_protein_coding_gene lincRNA.36 CR44080 16-Dec-15 2015_12 FBgn0005719 l(1)TK127 lethal (1) TK127 http://flybase.net/reports/FBgn0005719.html gene l127 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0266726 CR45199 http://flybase.net/reports/FBgn0266726.html non_protein_coding_gene CR45199 16-Dec-15 2015_12 FBgn0040736 IM3 Immune induced molecule 3 http://flybase.net/reports/FBgn0040736.html FBgn0064795 protein_coding_gene "0006952=defense response, 0009617=response to bacterium, 0019731=antibacterial humoral response, 0008063=Toll signaling pathway" 0005576=extracellular region "CG16844, BcDNA:RH58911, DIM 3, CT37419, im3" IPR013172=Immune-induced protein Dim CG16844 16-Dec-15 2015_12 viable FBgn0030429 CG4661 http://flybase.net/reports/FBgn0030429.html protein_coding_gene 0006511=ubiquitin-dependent protein catabolic process "IPR016072=SKP1 component, dimerisation" CG4661 16-Dec-15 2015_12 viable FBgn0032204 CG4953 http://flybase.net/reports/FBgn0032204.html protein_coding_gene IPR010378=Protein of unknown function DUF974 CG4953 16-Dec-15 2015_12 ENSDARG00000033768(zgc:73187) WBGene00016964(C56C10.7) ENSXETG00000000453(C5orf44) ENSMUSG00000021711(2410002O22Rik) ENSG00000113597(C5orf44) viable FBgn0267062 CR45506 http://flybase.net/reports/FBgn0267062.html non_protein_coding_gene CR45506 16-Dec-15 2015_12 FBgn0041593 l(3)HC1 lethal (3) HC1 http://flybase.net/reports/FBgn0041593.html gene unnamed 16-Dec-15 2015_12 lethal FBgn0013652 ms(2)ry8 ms(2)ry8 http://flybase.net/reports/FBgn0013652.html gene "ms(2)8, unnamed" 16-Dec-15 2015_12 male sterile FBgn0013985 Inr-b Inverse regulator b http://flybase.net/reports/FBgn0013985.html gene 16-Dec-15 2015_12 "visible,dominant" FBgn0060532 l(3)S101003b lethal (3) S101003b http://flybase.net/reports/FBgn0060532.html gene 1010/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0069957 CG41061 http://flybase.net/reports/FBgn0069957.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002604 M(2)56CD Minute (2) 56CD http://flybase.net/reports/FBgn0002604.html gene M(2)b 16-Dec-15 2015_12 "Minute,dominant,visible" "macrochaeta,adult abdomen" FBgn0000184 BicF Bicaudal F http://flybase.net/reports/FBgn0000184.html gene bicF 16-Dec-15 2015_12 "female sterile,dominant,maternal effect" "egg,maternal effect,embryo" FBgn0281844 BG00197 http://flybase.net/reports/FBgn0281844.html gene 16-Dec-15 2015_12 FBgn0050055 CR30055 http://flybase.net/reports/FBgn0050055.html FBgn0047248 non_protein_coding_gene "BcDNA:GM14547, CG30055" CR30055 16-Dec-15 2015_12 viable FBgn0036873 CG18294 http://flybase.net/reports/FBgn0036873.html protein_coding_gene BcDNA:RE51966 CG18294 16-Dec-15 2015_12 DRSC09891 K -0.969586554 -0.326667177 -0.027300316 0.032241069 -1.529049185 -0.449102247 FBgn0034313 CG5726 http://flybase.net/reports/FBgn0034313.html protein_coding_gene 0005811=lipid particle IPR016021=MIF4G-like domain CG5726 16-Dec-15 2015_12 FBgn0267988 CR46255 http://flybase.net/reports/FBgn0267988.html non_protein_coding_gene CR46255 16-Dec-15 2015_12 FBgn0266071 CR44824 http://flybase.net/reports/FBgn0266071.html non_protein_coding_gene CR44824 16-Dec-15 2015_12 FBgn0266163 CG44869 http://flybase.net/reports/FBgn0266163.html protein_coding_gene CG44869 16-Dec-15 2015_12 FBgn0002951 nofD no object fixation D http://flybase.net/reports/FBgn0002951.html gene 16-Dec-15 2015_12 adult central nervous system FBgn0052749 CR32749 http://flybase.net/reports/FBgn0052749.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0265703 CR44510 http://flybase.net/reports/FBgn0265703.html non_protein_coding_gene CR44510 16-Dec-15 2015_12 FBgn0085643 CG41421 http://flybase.net/reports/FBgn0085643.html FBan0041421 protein_coding_gene 16-Dec-15 2015_12 FBgn0036947 obst-F obstructor-F http://flybase.net/reports/FBgn0036947.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region CG7306 IPR002557=Chitin binding domain CG7306 16-Dec-15 2015_12 FBgn0038993 CG13843 http://flybase.net/reports/FBgn0038993.html protein_coding_gene CG13843 16-Dec-15 2015_12 viable FBgn0035167 Gr61a Gustatory receptor 61a http://flybase.net/reports/FBgn0035167.html protein_coding_gene "0033041=sweet taste receptor activity, 0008527=taste receptor activity" "0050912=detection of chemical stimulus involved in sensory perception of taste, 0050909=sensory perception of taste, 0050916=sensory perception of sweet taste" 0016021=integral component of membrane "Dmel61a, CG13888, Gr61D1, GR61a, Gustatory receptor 61D1" IPR009318=Gustatory receptor CG13888 16-Dec-15 2015_12 WBGene00001804(gur-3) taste perception defective FBgn0028008 l(3)S114709 lethal (3) S114709 http://flybase.net/reports/FBgn0028008.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038552 CG18012 http://flybase.net/reports/FBgn0038552.html protein_coding_gene "0019187=beta-1,4-mannosyltransferase activity" 0006486=protein glycosylation "Alg1, dAlg1" "IPR026051=Asparagine-linked glycosylation protein 1-like, IPR028098=Glycosyltransferase subfamily 4-like, N-terminal domain" CG18012 16-Dec-15 2015_12 ENSDARG00000054963(alg1) YBR110W(ALG1) WBGene00020820(T26A5.4) ENSXETG00000025674(BC091059.1-001) ENSMUSG00000039427(Alg1) ENSG00000033011(ALG1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0010085 Ssb Small synaptic boutons http://flybase.net/reports/FBgn0010085.html gene "0045202=synapse, 0005634=nucleus" 16-Dec-15 2015_12 " larval stage , oogenesis stage,larval stage , larval stage && spermatogenesis " " abdominal 2--7 ventral acute muscle 3

, abdominal 2--7 ventral acute muscle 2

, abdominal 2--7 ventral longitudinal muscle 1

, somatic muscle

, abdominal 2--7 dorsal acute muscle 3

, abdominal 2--7 dorsal oblique muscle 2

, synapse

, abdominal 2--7 ventral longitudinal muscle 2

, ovary

{ 0 shi* } , abdominal 2--7 segment border muscle

, abdominal 2--7 lateral transverse muscle 2

, abdominal 2--7 ventral oblique muscle 5

, central nervous system

, abdominal 2--7 ventral oblique muscle 1

, abdominal 2--7 dorsal acute muscle 2

, testis

, larval brain | restricted

, abdominal 2--7 ventral acute muscle 1

, abdominal 2--7 ventral oblique muscle 6

, abdominal 2--7 dorsal oblique muscle 1

, abdominal 2--7 dorsal acute muscle 1

, ventral nerve cord

, abdominal 2--7 ventral oblique muscle 4

, abdominal 2--7 ventral oblique muscle 2

, neuropil

" FBgn0037013 CG13250 http://flybase.net/reports/FBgn0037013.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG13250 16-Dec-15 2015_12 viable FBgn0066326 rux::Dere\rux rux::Dere\rux http://flybase.net/reports/FBgn0066326.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0030921 CG6290 http://flybase.net/reports/FBgn0030921.html FBgn0062506 protein_coding_gene BcDNA:GH02837 CG6290 16-Dec-15 2015_12 viable FBgn0052746 CR32746 http://flybase.net/reports/FBgn0052746.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0003621 Su(var)2-144 Suppressor of variegation 2-144 http://flybase.net/reports/FBgn0003621.html gene 16-Dec-15 2015_12 FBgn0031275 GABA-B-R3 metabotropic GABA-B receptor subtype 3 http://flybase.net/reports/FBgn0031275.html "FBgn0046594, FBgn0046602" protein_coding_gene 0004965=G-protein coupled GABA receptor activity "0007186=G-protein coupled receptor signaling pathway, 0030431=sleep" 0016021=integral component of membrane "anon-WO0170980.14, D-Gaba3, anon-WO0170980.13, GB3, GABA[[B]]R3, GABA B R3, GABA[[B]]-R3, D-GABA[[B]]R3, CG3022, GABA-B receptor subtype 3" "IPR028082=Periplasmic binding protein-like I, IPR017978=GPCR, family 3, C-terminal, IPR001828=Receptor, ligand binding region, IPR002456=GPCR, family 3, gamma-aminobutyric acid receptor, type B1, IPR000337=GPCR, family 3, IPR002455=GPCR, family 3, gamma-aminobutyric acid receptor, type B" CG3022 16-Dec-15 2015_12 circadian rhythm defective FBgn0052133 Ptip PAX transcription activation domain interacting protein http://flybase.net/reports/FBgn0052133.html "FBgn0036399, FBgn0036400" protein_coding_gene 0008134=transcription factor binding "0002805=regulation of antimicrobial peptide biosynthetic process, 0016571=histone methylation, 0051568=histone H3-K4 methylation, 0007448=anterior/posterior pattern specification, imaginal disc, 0009880=embryonic pattern specification" 0044666=MLL3/4 complex "PTIP, CG8797, CG6532, CG32133, ptip" IPR001357=BRCT domain CG32133 16-Dec-15 2015_12 "ENSG00000206481,ENSG00000206385,ENSG00000137337(MDC1)" "lethal,recessive,viable,visible" "denticle belt,germline clone,maternal effect,imaginal disc,trichogen cell" DRSC11048 IK -2.816744025 -0.712488958 -0.897331797 0.247900942 1.305952913 2.071406627 FBgn0036676 CG13028 http://flybase.net/reports/FBgn0036676.html protein_coding_gene CG13028 16-Dec-15 2015_12 viable FBgn0028636 ifm(2)RU6 indirect flight muscle (2) RU6 http://flybase.net/reports/FBgn0028636.html gene 0007517=muscle organ development 0005703=polytene chromosome puff 16-Dec-15 2015_12 "visible,recessive,flight defective,fertile,viable,reduced" "indirect flight muscle,wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0014325 l(3)ry50 lethal (3) ry50 http://flybase.net/reports/FBgn0014325.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260314 GSd216 http://flybase.net/reports/FBgn0260314.html gene 16-Dec-15 2015_12 lethal FBgn0035702 CG10147 http://flybase.net/reports/FBgn0035702.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG10147 16-Dec-15 2015_12 WBGene00004773(sem-4) viable FBgn0065709 l(2)SH0608 lethal (2) SH0608 http://flybase.net/reports/FBgn0065709.html gene l(2)SH2 0608 16-Dec-15 2015_12 "lethal,recessive" FBgn0053348 CheB42a Chemosensory protein B 42a http://flybase.net/reports/FBgn0053348.html FBgn0033120 protein_coding_gene "0008289=lipid binding, 0016247=channel regulator activity, 0044325=ion channel binding" "0043695=detection of pheromone, 0019236=response to pheromone, 0008049=male courtship behavior, 0007606=sensory perception of chemical stimulus" "0005576=extracellular region, 0005615=extracellular space, 0043234=protein complex" "CheB42A, CheB42a, CG33348, CG15242" "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG33348 16-Dec-15 2015_12 adult stage | male " prothoracic tarsal segment 3

, prothoracic tarsal segment 2

, prothoracic tarsal segment

, prothoracic tarsal segment 1

, head

, prothoracic tarsal segment 4

" " pupal stage | late , adult stage | male " prothoracic leg

"mating rhythm defective,taste perception defective,courtship behavior defective,behavior defective,viable" FBgn0031737 obst-E obstructor-E http://flybase.net/reports/FBgn0031737.html protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" 0006030=chitin metabolic process 0005576=extracellular region "CG11142, Obst-E" IPR002557=Chitin binding domain CG11142 16-Dec-15 2015_12 FBgn0013703 mt:tRNA:Q mitochondrial glutamine tRNA http://flybase.net/reports/FBgn0013703.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "glutamine tRNA, CR34061, mtdbD00006293, tRNA[gln]" CR34061 16-Dec-15 2015_12 FBgn0031104 jb jean-baptiste http://flybase.net/reports/FBgn0031104.html protein_coding_gene 0035074=pupation CG15460 CG15460 16-Dec-15 2015_12 "viable,partially lethal - majority live,male limited,some die during pharate adult stage,male fertile" FBgn0029608 CG3091 http://flybase.net/reports/FBgn0029608.html "FBtr0070416, FBpp0070400" protein_coding_gene "0005215=transporter activity, 0008431=vitamin E binding" 0006810=transport 0005622=intracellular "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG3091 16-Dec-15 2015_12 viable DRSC18274 I 1.802697402 0.841848078 0.061033382 0.116129833 0.553833087 -0.16742402 FBgn0001364 l(1)1Fc lethal (1) 1Fc http://flybase.net/reports/FBgn0001364.html gene JA29 16-Dec-15 2015_12 "lethal,cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0267993 CR46260 http://flybase.net/reports/FBgn0267993.html non_protein_coding_gene CR46260 16-Dec-15 2015_12 FBgn0267168 CR45608 http://flybase.net/reports/FBgn0267168.html non_protein_coding_gene CR45608 16-Dec-15 2015_12 FBgn0266832 CR45294 http://flybase.net/reports/FBgn0266832.html non_protein_coding_gene CR45294 16-Dec-15 2015_12 FBgn0052708 CG32708 http://flybase.net/reports/FBgn0052708.html FBgn0030084 protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" 0022008=neurogenesis CG6997 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG32708 16-Dec-15 2015_12 ENSDARG00000043666(zgc:109995) YNR054C(ESF2) WBGene00019005(F57B10.8) ENSXETG00000005684(ABT1) ENSMUSG00000036376(Abt1) ENSG00000146109(ABT1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0005063 fs(2)OW203 female sterile (2) OW203 http://flybase.net/reports/FBgn0005063.html gene 16-Dec-15 2015_12 FBgn0067737 l(1)G0352 lethal (1) G0352 http://flybase.net/reports/FBgn0067737.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0040167 l(1)G0376 lethal (1) G0376 http://flybase.net/reports/FBgn0040167.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0034420 CG10737 http://flybase.net/reports/FBgn0034420.html protein_coding_gene 0019992=diacylglycerol binding 0035556=intracellular signal transduction "Gene 1, 10737" "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000008=C2 domain" CG10737 16-Dec-15 2015_12 WBGene00020012(R11G1.6) "viable,visible" trichogen cell FBgn0265894 CR44683 http://flybase.net/reports/FBgn0265894.html non_protein_coding_gene lincRNA.633 CR44683 16-Dec-15 2015_12 FBgn0002350 l(3)87Db lethal (3) 87Db http://flybase.net/reports/FBgn0002350.html gene "S5, 0091/13, l(3)S5" 16-Dec-15 2015_12 "lethal,recessive" FBgn0065812 l(2)SH0383 lethal (2) SH0383 http://flybase.net/reports/FBgn0065812.html gene l(2)SH2 0383 16-Dec-15 2015_12 "lethal,recessive" FBgn0060298 p69 p69 http://flybase.net/reports/FBgn0060298.html gene 0042169=SH2 domain binding 16-Dec-15 2015_12 FBgn0031189 CG14618 http://flybase.net/reports/FBgn0031189.html protein_coding_gene 0008168=methyltransferase activity "IPR016009=tRNA methyltransferase TRMD/TRM10-type domain, IPR007356=tRNA (guanine-N1-)-methyltransferase, eukaryotic, IPR016653=tRNA (guanine(9)-N(1))-methyltransferase TRM10, IPR028564=tRNA methyltransferase TRM10-type domain" CG14618 16-Dec-15 2015_12 ENSDARG00000036678 YOL093W(TRM10) WBGene00009131(F25H8.1) ENSXETG00000012132(rg9mtd2) ENSMUSG00000004127(Rg9mtd2) ENSG00000145331(RG9MTD2) "viable,fertile" FBgn0033447 dila dilatory http://flybase.net/reports/FBgn0033447.html protein_coding_gene "0048935=peripheral nervous system neuron development, 0035735=intraciliary transport involved in cilium morphogenesis, 0035082=axoneme assembly, 0007283=spermatogenesis, 0042073=intraciliary transport, 0008344=adult locomotory behavior, 0042384=cilium assembly" "0035869=ciliary transition zone, 0000242=pericentriolar material" "CG1625, CG1626, Dila" IPR030465=Centrosomal protein of 131 kDa CG1625 16-Dec-15 2015_12 ENSXETG00000016930(TEgg017b09.1) ENSMUSG00000039781(Azi1) ENSG00000141577(AZI1) "viable,uncoordinated,recessive,bang sensitive,short lived,male semi-sterile" "cilium,axonemal microtubule,axonemal dynein complex,spermatozoon,microtubule-based flagellum" FBgn0000718 Forkoid Forkoid http://flybase.net/reports/FBgn0000718.html gene Fo 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" "head bristle,macrochaeta & adult thorax | posterior,macrochaeta" FBgn0025734 sca::Hsap\FGA sca::Hsap\FGA http://flybase.net/reports/FBgn0025734.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing,wing vein" FBgn0041152 grim::rpr grim::rpr http://flybase.net/reports/FBgn0041152.html engineered_fusion_gene 16-Dec-15 2015_12 "increased cell death,lethal,visible,heat sensitive,eye color defective" "midline glial cell,eye,pigment cell,ommatidium,heat sensitive" FBgn0264603 CR43952 http://flybase.net/reports/FBgn0264603.html non_protein_coding_gene CG43952 CR43952 16-Dec-15 2015_12 FBgn0015364 anon-topo anon-topoisomerase II cleavage sites http://flybase.net/reports/FBgn0015364.html region 16-Dec-15 2015_12 FBgn0033051 Strica Ser/Thr-rich caspase http://flybase.net/reports/FBgn0033051.html protein_coding_gene 0004197=cysteine-type endopeptidase activity "0046672=positive regulation of compound eye retinal cell programmed cell death, 0045476=nurse cell apoptotic process, 0006508=proteolysis, 0035070=salivary gland histolysis, 0012501=programmed cell death" 0005737=cytoplasm "STRICA, Dream/Strica, CG7863, Dream, DREAM, Strica, Strica/Dream, Ser/Thr-RIch-CAspase, strica, dream, STRICA/DREAM" "IPR002138=Peptidase C14, caspase non-catalytic subunit p10, IPR029030=Caspase-like domain, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR011600=Peptidase C14, caspase domain, IPR015917=Peptidase C14A, caspase precursor p45, core" CG7863 16-Dec-15 2015_12 pupal stage salivary gland

"decreased cell death,neuroanatomy defective,viable,fertile,visible,cell death defective" "peptidergic neuron,ectopic,eye,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage,egg chamber" FBgn0013300 ProtA Protamine A http://flybase.net/reports/FBgn0013300.html "FBgn0010308, FBgn0063695" protein_coding_gene 0003677=DNA binding "0035093=spermatogenesis, exchange of chromosomal proteins, 0035092=sperm chromatin condensation, 0007286=spermatid development" 0000785=chromatin "CG4479, mst35Ba, BG:DS03431.2, Male-specific-transcript-35Ba, dProtA, ProtamineA, Protamine, ProtA, BcDNA:AT31403, mst35b, Mst35Ba, Protamine A, protamine (mst35Ba), protamine A, protA, protamine, dProtamineA, mst35B" "IPR024460=Protein of unknown function DUF1074, IPR009071=High mobility group box domain" CG4479 16-Dec-15 2015_12 viable FBgn0266138 CR44844 http://flybase.net/reports/FBgn0266138.html non_protein_coding_gene CR44844 16-Dec-15 2015_12 FBgn0037667 CG16734 http://flybase.net/reports/FBgn0037667.html protein_coding_gene CG16734 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0027306 l(1)G0116 lethal (1) G0116 http://flybase.net/reports/FBgn0027306.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0058376 CG40376 http://flybase.net/reports/FBgn0058376.html FBan0040376 protein_coding_gene 16-Dec-15 2015_12 FBgn0027291 l(1)G0156 lethal (1) G0156 http://flybase.net/reports/FBgn0027291.html FBgn0031024 protein_coding_gene "0000287=magnesium ion binding, 0004449=isocitrate dehydrogenase (NAD+) activity, 0051287=NAD binding" 0006099=tricarboxylic acid cycle "0005811=lipid particle, 0005739=mitochondrion, 0005759=mitochondrial matrix, 0005875=microtubule associated complex" "l(1)G0156, CG12233, l (1) G0156, FBgn0031024, Lethal(1)G0156, isocitrate dehydrogenase" "IPR004434=Isocitrate dehydrogenase NAD-dependent, IPR001804=Isocitrate and isopropylmalate dehydrogenases family, IPR024084=Isopropylmalate dehydrogenase-like domain, IPR019818=Isocitrate/isopropylmalate dehydrogenase, conserved site" CG12233 16-Dec-15 2015_12 ENSDARG00000030278(idh3a) YOR136W(IDH2) WBGene00009664(F43G9.1) ENSXETG00000009754(idh3a) ENSMUSG00000032279(Idh3a) ENSG00000166411(IDH3A) "viable,fertile,lethal,recessive,visible" trichogen cell FBgn0259455 C411 http://flybase.net/reports/FBgn0259455.html gene 16-Dec-15 2015_12 visible wing hair FBgn0037178 CG12546 http://flybase.net/reports/FBgn0037178.html FBgn0063008 protein_coding_gene BcDNA:RE45259 CG12546 16-Dec-15 2015_12 DRSC11676 EK 0.511186168 -0.009471605 0.397126188 -1.520763728 -1.796128582 -0.606801452 FBgn0039628 CG11841 http://flybase.net/reports/FBgn0039628.html "FBgn0044569, FBgn0044697, FBgn0064952" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP45, BcDNA:GH26583, anon-WO0140519.6, anon-WO0140519.18" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG11841 16-Dec-15 2015_12 "ENSXETG00000016792(plat),ENSXETG00000007245(F12),ENSXETG00000005495(HGFAC),ENSXETG00000018616(HABP2),ENSXETG00000010002(),ENSXETG00000004035(PRSS12)" "ENSMUSG00000025075(Habp2),ENSMUSG00000029102(Hgfac),ENSMUSG00000031538(Plat),ENSMUSG00000021822(Plau),ENSMUSG00000021492(F12),ENSMUSG00000027978(Prss12)" "partially lethal - majority die,some die during pupal stage" FBgn0026618 verfilzt verfilzt http://flybase.net/reports/FBgn0026618.html gene 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,commissure" FBgn0000710 Flutter Flutter http://flybase.net/reports/FBgn0000710.html gene Flu 16-Dec-15 2015_12 "flightless,semidominant,behavior defective,recessive,dominant" "dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle" FBgn0263958 BG01403 http://flybase.net/reports/FBgn0263958.html gene 16-Dec-15 2015_12 "long lived,starvation stress response defective,male limited,temperature response defective" FBgn0067050 Rst(2)DDT-WIS1 Resistant to DDT on II Wisconsin 1 http://flybase.net/reports/FBgn0067050.html gene "0046680=response to DDT, 0046683=response to organophosphorus, 0017085=response to insecticide" "Rst(2)DDT, Resistant to DDT on II" 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0031285 CG3662 http://flybase.net/reports/FBgn0031285.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space IPR007084=BRICHOS domain CG3662 16-Dec-15 2015_12 "ENSDARG00000041505(itm2bb),ENSDARG00000007098(itm2ba),ENSDARG00000039650(itm2cb),ENSDARG00000043448(itm2ca)" WBGene00016106(C25F6.7) "ENSXETG00000024684(itm2b),ENSXETG00000027280(itm2a)" "ENSMUSG00000031239(Itm2a),ENSMUSG00000022108(Itm2b),ENSMUSG00000026223(Itm2c)" "ENSG00000136156(ITM2B),ENSG00000135916(ITM2C),ENSG00000078596(ITM2A)" "viable,fertile" FBgn0261967 huc2L-16 hydroxyurea- and (or) caffeine-sensitive 2L-16 http://flybase.net/reports/FBgn0261967.html gene huc[2L-16] 16-Dec-15 2015_12 "chemical sensitive,somatic clone,partially lethal - majority live" "eye,somatic clone,drug conditional" FBgn0260231 CG42505 http://flybase.net/reports/FBgn0260231.html protein_coding_gene CG42505 16-Dec-15 2015_12 FBgn0035812 CG7457 http://flybase.net/reports/FBgn0035812.html protein_coding_gene CT13960 "IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG7457 16-Dec-15 2015_12 WBGene00010498(K02B12.5) ENSXETG00000020475() ENSMUSG00000059323(Nfkbil2) ENSG00000160949(TONSL) viable FBgn0014245 l(2)32Af lethal (2) 32Af http://flybase.net/reports/FBgn0014245.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266578 CR45109 http://flybase.net/reports/FBgn0266578.html non_protein_coding_gene CR45109 16-Dec-15 2015_12 FBgn0267146 CR45586 http://flybase.net/reports/FBgn0267146.html non_protein_coding_gene CR45586 16-Dec-15 2015_12 FBgn0031442 Prosë_4R1 Proteasome ë_4 subunit-related 1 http://flybase.net/reports/FBgn0031442.html FBgn0061441 protein_coding_gene 0004298=threonine-type endopeptidase activity 0006511=ubiquitin-dependent protein catabolic process 0005839=proteasome core complex "CG17301, BcDNA:AT30033, Proteasome beta4R1 subunit, beta4R1" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR001353=Proteasome, subunit alpha/beta, IPR016050=Proteasome beta-type subunit, conserved site" CG17301 16-Dec-15 2015_12 YER012W(PRE1) WBGene00003950(pbs-4) ENSXETG00000009668(PSMB2) viable FBgn0003233 ref(3)O refractory to sigma O http://flybase.net/reports/FBgn0003233.html gene refractaire(2)Oregon 16-Dec-15 2015_12 FBgn0035439 CG14961 http://flybase.net/reports/FBgn0035439.html protein_coding_gene CG14961 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040285 Scamp Scamp http://flybase.net/reports/FBgn0040285.html "FBgn0025248, FBgn0030637, FBgn0047275" protein_coding_gene "0007274=neuromuscular synaptic transmission, 0031987=locomotion involved in locomotory behavior, 0015031=protein transport, 0009408=response to heat, 0016079=synaptic vesicle exocytosis, 0007616=long-term memory" "0030424=axon, 0016021=integral component of membrane, 0008021=synaptic vesicle, 0043195=terminal bouton" "CG9195, Sc, anon-EST:fe1F7, BcDNA:GM04934, anon-fast-evolving-1F7, dmSCAMP, SCAMP, dmSC" IPR007273=SCAMP CG9195 16-Dec-15 2015_12 "ENSDARG00000036911(scamp1),ENSDARG00000017010(scamp2l),ENSDARG00000016765(zgc:103488),ENSDARG00000010279(scamp2)" WBGene00004743(scm-1) "ENSXETG00000000547(scamp1),ENSXETG00000025486(scamp2)" "ENSMUSG00000021687(Scamp1),ENSMUSG00000040188(Scamp2),ENSMUSG00000028049(Scamp3)" "ENSG00000116521(SCAMP3),ENSG00000085365,ENSG00000140497(SCAMP2)" viable DRSC20286 I 1.768355394 -0.45673758 0.063663516 0.305190159 1.165449423 -0.070402274 FBgn0263550 mir-4918 mir-4918 stem loop http://flybase.net/reports/FBgn0263550.html miRNA_gene "CR43535, dme-mir-4918" CR43535 16-Dec-15 2015_12 FBgn0024531 l(3)L0539 lethal (3) L0539 http://flybase.net/reports/FBgn0024531.html gene EP(3)3083 16-Dec-15 2015_12 "lethal,recessive,visible,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,wing" FBgn0053293 CG33293 http://flybase.net/reports/FBgn0053293.html "FBgn0037303, FBgn0045091, FBgn0045105, FBgn0045379, FBgn0045394, FBgn0046802" protein_coding_gene "bs06b05.y1, bs34a01.y1, NEST:bs06b05, NEST:bs34a01, bs07d08.y1, NEST:bs07d08, NEST:bs35d06, BcDNA:GH07964, CG12163, bs35d06.y1" CG33293 16-Dec-15 2015_12 FBgn0084480 fz::wntD fz::wntD http://flybase.net/reports/FBgn0084480.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0084819 l(3)S026238 l(3)S026238 http://flybase.net/reports/FBgn0084819.html gene 16-Dec-15 2015_12 FBgn0052719 CG32719 http://flybase.net/reports/FBgn0052719.html protein_coding_gene "IPR015880=Zinc finger, C2H2-like" CG32719 16-Dec-15 2015_12 FBgn0262696 Su(VGlut)B36 http://flybase.net/reports/FBgn0262696.html gene B36 16-Dec-15 2015_12 FBgn0029660 CG10801 http://flybase.net/reports/FBgn0029660.html protein_coding_gene IPR011705=BTB/Kelch-associated CG10801 16-Dec-15 2015_12 viable FBgn0026642 l(2)k08401a lethal (2) k08401a http://flybase.net/reports/FBgn0026642.html gene l(2)k08401 16-Dec-15 2015_12 lethal FBgn0015855 anon-12Eb anon-12Eb http://flybase.net/reports/FBgn0015855.html gene unnamed 16-Dec-15 2015_12 FBgn0011132 l(1)Q206 lethal (1) Q206 http://flybase.net/reports/FBgn0011132.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0058336 CG40336 http://flybase.net/reports/FBgn0058336.html FBan0040336 protein_coding_gene 16-Dec-15 2015_12 FBgn0035461 ntc nutcracker http://flybase.net/reports/FBgn0035461.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0050821=protein stabilization, 0007291=sperm individualization, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "nutcracker, FBXO7, CG10855" IPR001810=F-box domain CG10855 16-Dec-15 2015_12 "viable,fertile,male sterile,sterile" "individualization stage spermatid,cystic bulge,sperm individualization complex" FBgn0267004 CR45448 http://flybase.net/reports/FBgn0267004.html non_protein_coding_gene CR45448 16-Dec-15 2015_12 FBgn0031661 Gmd "GDP-mannose 4,6-dehydratase" http://flybase.net/reports/FBgn0031661.html FBgn0065398 protein_coding_gene "0008446=GDP-mannose 4,6-dehydratase activity" "2000035=regulation of stem cell division, 0007219=Notch signaling pathway, 0048477=oogenesis, 0042351='de novo' GDP-L-fucose biosynthetic process, 0019673=GDP-mannose metabolic process, 0042350=GDP-L-fucose biosynthetic process" "GDP-mannose 4,6 dehydratase, GDP-mannose dehydratase, l(2)SH2 1606, CG8890, GDP-D-mannose 4,6-dehydratase, l(2)SH1606, GDP-mannose 4,6-dehydrase, gmd, DmGMD, Brazil nut, Dm-gmd, GMD" "IPR016040=NAD(P)-binding domain, IPR006368=GDP-mannose 4,6-dehydratase" CG8890 16-Dec-15 2015_12 ENSDARG00000026629(gmds) "WBGene00010166(gmd-2),WBGene00000266(bre-1)" ENSXETG00000000600(gmds) ENSMUSG00000038372(Gmds) ENSG00000112699(GMDS) "lethal,recessive,visible,conditional,size defective,viable,fertile,germline clone,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "eye disc,eye,conditional,wing,egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell,wing disc,intestinal stem cell,supernumerary" FBgn0265051 CR44166 http://flybase.net/reports/FBgn0265051.html non_protein_coding_gene CR44166 16-Dec-15 2015_12 FBgn0031848 Nse1 Non-SMC element 1 http://flybase.net/reports/FBgn0031848.html FBgn0061614 protein_coding_gene "0019789=SUMO transferase activity, 0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0006281=DNA repair, 0016567=protein ubiquitination, 2001022=positive regulation of response to DNA damage stimulus" "0030915=Smc5-Smc6 complex, 0005634=nucleus" "EST2, GM14348, Nse1, anon-WO0118547.82, NSE1, CG11329, unnamed" "IPR011513=Non-structural maintenance of chromosomes element 1, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR014857=Zinc finger, RING-like" CG11329 16-Dec-15 2015_12 ENSDARG00000034662(nsmce1) ENSXETG00000025443(Q6P881_XENTR) ENSMUSG00000030750(Nsmce1) ENSG00000169189(NSMCE1) viable FBgn0029114 Tollo Tollo http://flybase.net/reports/FBgn0029114.html FBgn0041571 protein_coding_gene 0004888=transmembrane signaling receptor activity "0007165=signal transduction, 0060049=regulation of protein glycosylation, 0048935=peripheral nervous system neuron development, 0002227=innate immune response in mucosa, 0003401=axis elongation, 0006952=defense response, 0060026=convergent extension" "0005886=plasma membrane, 0016021=integral component of membrane" "CG6890, toll, dToll8, Tl-8, tollo/toll-8, CT21344, tollo, TOLL 8, dTLR8, toll receptor, Toll-8" "IPR003591=Leucine-rich repeat, typical subtype, IPR026906=Leucine rich repeat 5, IPR000372=Leucine-rich repeat N-terminal domain, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR001611=Leucine-rich repeat" CG6890 16-Dec-15 2015_12 "ENSDARG00000019742,ENSDARG00000022048(tlr4bb)" WBGene00006593(tol-1) "ENSXETG00000021933(),ENSXETG00000017689(),ENSXETG00000021898()" ENSMUSG00000033777(Tlr13) ENSG00000100399(CHADL) embryonic stage -- adult stage "lethal,viable,fertile,partially lethal - majority live,visible,cold sensitive,dominant" "adult abdomen,macrochaeta,ectopic,eye,wing vein,leg,wing,wing disc,ventral thoracic disc,tibia,tarsal segment,femur,cold sensitive,mesothoracic tergum,wing pouch,somatic clone" FBgn0027970 l(3)S142916 lethal (3) S142916 http://flybase.net/reports/FBgn0027970.html gene "1429/16, 1400/09, 0510/01, 0925/01" 16-Dec-15 2015_12 "lethal,recessive" FBgn0082943 snoRNA:Me28S-A982a snoRNA:Me28S-A982a http://flybase.net/reports/FBgn0082943.html snoRNA_gene "Me28S-A982a(DmSnR39/59), CR34527, DmSnR39/59a, Me28S-Am982a" CR34527 16-Dec-15 2015_12 FBgn0001163 GustR Gustatory R http://flybase.net/reports/FBgn0001163.html gene 16-Dec-15 2015_12 "taste perception defective,dominant" taste bristle FBgn0016825 l(1)MZ12 lethal (1) MZ12 http://flybase.net/reports/FBgn0016825.html gene M12 16-Dec-15 2015_12 "lethal,recessive" FBgn0259223 CG42323 http://flybase.net/reports/FBgn0259223.html "FBgn0030919, FBgn0052550" protein_coding_gene "CG15055, CG32550" CG42323 16-Dec-15 2015_12 FBgn0259200 CG42304 http://flybase.net/reports/FBgn0259200.html "FBgn0035362, FBgn0035363, FBan0032297, FBgn0052297" protein_coding_gene "CG32297, CG1248" CG42304 16-Dec-15 2015_12 ENSXETG00000014910(DNTTIP1) ENSMUSG00000017299(Dnttip1) ENSG00000101457(DNTTIP1) DRSC08277 E 1.407295649 0.264927075 1.554187307 0.009826797 0.957795885 -0.795477802 FBgn0050269 CG30269 http://flybase.net/reports/FBgn0050269.html FBgn0034762 protein_coding_gene CG13515 IPR006629=LPS-induced tumour necrosis factor alpha factor CG30269 16-Dec-15 2015_12 WBGene00013604(Y87G2A.18) "viable,visible" trichogen cell FBgn0031752 CG9044 http://flybase.net/reports/FBgn0031752.html protein_coding_gene 0019901=protein kinase binding 0008104=protein localization 0005737=cytoplasm "mdcds_8484, CT25972" IPR001611=Leucine-rich repeat CG9044 16-Dec-15 2015_12 ENSXETG00000007155(stk11ip) ENSMUSG00000026213(Stk11ip) ENSG00000144589(STK11IP) viable FBgn0024285 Srp54 Srp54 http://flybase.net/reports/FBgn0024285.html FBgn0025965 protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0008187=poly-pyrimidine tract binding" "0010468=regulation of gene expression, 0022008=neurogenesis, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0006376=mRNA splice site selection, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0031440=regulation of mRNA 3'-end processing" "0005634=nucleus, 0071011=precatalytic spliceosome, 0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome" "CG4602, clone 2.16, anon-EST:Liang-2.16, dSRp54, p75, SRp54" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG4602 16-Dec-15 2015_12 "ENSDARG00000004342(srsf11),ENSDARG00000009764(zgc:100974)" WBGene00004704(rsp-7) ENSXETG00000021460(SFRS12) "ENSMUSG00000032621(Srsf12),ENSMUSG00000055436(Srsf11)" "ENSG00000153914(SREK1),ENSG00000116754(SRSF11)" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC03442 IK -1.848458329 -1.322251605 -0.028225757 0.025790837 2.231589329 1.590925595 FBgn0041722 rsh rsh http://flybase.net/reports/FBgn0041722.html gene "0006952=defense response, 0009617=response to bacterium" red shirt 16-Dec-15 2015_12 immune response defective FBgn0036810 CG6885 http://flybase.net/reports/FBgn0036810.html FBgn0061709 protein_coding_gene anon-WO0118547.731 CG6885 16-Dec-15 2015_12 "viable,fertile" DRSC10740 I 1.968592489 0.206287051 -0.902799763 -0.107821366 1.451330245 0.601961836 FBgn0001561 l(1)19Ed lethal (1) 19Ed http://flybase.net/reports/FBgn0001561.html "FBgn0001731, FBgn0011263, FBgn0011264" gene "D83, l(1)EC235, l(1)ESHS52, HM-435, D76, EC235" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0026143 CDC45L CDC45L http://flybase.net/reports/FBgn0026143.html FBgn0014904 protein_coding_gene "0003682=chromatin binding, 0043138=3'-5' DNA helicase activity, 0003677=DNA binding" "1900087=positive regulation of G1/S transition of mitotic cell cycle, 0007095=mitotic G2 DNA damage checkpoint, 0030261=chromosome condensation, 0022008=neurogenesis, 0006277=DNA amplification, 0048812=neuron projection morphogenesis, 0006270=DNA replication initiation, 0006260=DNA replication" "0005656=nuclear pre-replicative complex, 0005737=cytoplasm, 0005634=nucleus" "Transcription unit D, dCDC45, D, DmCdc45, dCDC45L, Cdc45, anon-1Ec, cdc45, CG3658, CDC45, EG:BACR7A4.11" IPR003874=CDC45 family CG3658 16-Dec-15 2015_12 ENSDARG00000043720(cdc45) YLR103C(CDC45) WBGene00009372(F34D10.2) ENSXETG00000018602(CDC45L) ENSMUSG00000000028(Cdc45) ENSG00000093009(CDC45) "lethal,some die during first instar larval stage,some die during second instar larval stage,radiation sensitive,neuroanatomy defective,viable,visible" "nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC17747 K -0.349668511 -1.40806763 -0.562534643 0.439386108 1.74261631 1.119926918 FBgn0266375 IP3K2 "Inositol 1,4,5-triphosphate kinase 2" http://flybase.net/reports/FBgn0266375.html "FBan0001630, FBgn0085388, FBgn0030471, FBgn0030470, FBgn0030469" protein_coding_gene "0048306=calcium-dependent protein binding, 0008440=inositol-1,4,5-trisphosphate 3-kinase activity, 0005516=calmodulin binding" "0035071=salivary gland cell autophagic cell death, 0032958=inositol phosphate biosynthetic process" 0005737=cytoplasm "CG34359, CG12724, CG15745, IP[[3]]K-2, dmIP3K2, CG4501, dmIP[[3]]beta, CG1630, CG45017, DIP3K2, dmIP3Kbeta, NP2758, D-IP3K2, IP[[3]]K2, ip3k2" IPR005522=Inositol polyphosphate kinase CG45017 16-Dec-15 2015_12 "ENSXETG00000002580(ITPKC),ENSXETG00000022603(ITPKB),ENSXETG00000002921(ITPKA)" ENSMUSG00000038855(Itpkb) ENSG00000143772(ITPKB) FBgn0027661 anon-H15 anon-H15 http://flybase.net/reports/FBgn0027661.html gene DMH#15 16-Dec-15 2015_12 FBgn0028091 l(3)S081003 lethal (3) S081003 http://flybase.net/reports/FBgn0028091.html gene "1473/10, 1459/11, 0528/04, 0693/07, 0770/08, 1472/07, 1225/01, 1199/06, 0810/03, 0073/29, l(3)S145911" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0035631 Txl Thioredoxin-like http://flybase.net/reports/FBgn0035631.html FBgn0062146 protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" "0006662=glycerol ether metabolic process, 0006974=cellular response to DNA damage stimulus, 0045454=cell redox homeostasis" "anon-WO0118547.248, thioredoxin-like, txl, Thioredoxin, 5495, CG5495" "IPR017937=Thioredoxin, conserved site, IPR013766=Thioredoxin domain, IPR010400=PITH domain, IPR008979=Galactose-binding domain-like, IPR005746=Thioredoxin, IPR012336=Thioredoxin-like fold" CG5495 16-Dec-15 2015_12 ENSDARG00000011921(txnl1) WBGene00021826(Y54E10A.3) ENSXETG00000020901(txnl1) ENSMUSG00000024583(Txnl1) ENSG00000091164(TXNL1) "viable,body color defective" mesothoracic tergum FBgn0264272 mwh multiple wing hairs http://flybase.net/reports/FBgn0264272.html "FBgn0260963, FBgn0002912, FBgn0035190, FBgn0054022, FBgn0082888" protein_coding_gene "0005515=protein binding, 0003779=actin binding" "0001736=establishment of planar polarity, 0035317=imaginal disc-derived wing hair organization, 0030837=negative regulation of actin filament polymerization, 2000039=regulation of trichome morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0035320=imaginal disc-derived wing hair site selection, 0016055=Wnt signaling pathway" "mwh, multiple wing hair, multiple Wing Hairs, CG34022, CG13913, BP1018, multiple wing hairs, multiple-wing-hairs, CG43772, unnamed" "IPR010472=Formin, FH3 domain, IPR014768=Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR016024=Armadillo-type fold" CG43772 16-Dec-15 2015_12 FBgn0005721 l(1)TK129 lethal (1) TK129 http://flybase.net/reports/FBgn0005721.html gene l129 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0065217 l(2)SH2244 lethal (2) SH2244 http://flybase.net/reports/FBgn0065217.html gene l(2)SH2 2244 16-Dec-15 2015_12 "lethal,recessive" FBgn0265002 CG44153 http://flybase.net/reports/FBgn0265002.html "FBgn0032180, FBgn0032179, FBgn0262032, FBgn0032182, FBgn0054048, FBgn0032186, FBgn0082877" protein_coding_gene 0004930=G-protein coupled receptor activity 0016020=membrane "CG5833, CG13136, unnamed, CG31714, CG13134, CG42843, BP1029, CG13132, CG34048" "IPR000742=EGF-like domain, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR000859=CUB domain, IPR013032=EGF-like, conserved site, IPR007110=Immunoglobulin-like domain, IPR001879=GPCR, family 2, extracellular hormone receptor domain" CG44153 16-Dec-15 2015_12 FBgn0085264 CG34235 http://flybase.net/reports/FBgn0085264.html protein_coding_gene CG34235 16-Dec-15 2015_12 FBgn0037389 CR10991 http://flybase.net/reports/FBgn0037389.html pseudogene_attribute CG10991 CR10991 16-Dec-15 2015_12 FBgn0261529 ms(2)34Fe male sterile (2) 34Fe http://flybase.net/reports/FBgn0261529.html "FBgn0028918, FBgn0002822" protein_coding_gene 0048515=spermatid differentiation "br40, BG:DS01068.1, ms34Fe, l(2)34Fe, ms(2)34Fh, CG15287, ms(2)br40" CG15287 16-Dec-15 2015_12 DRSC01905 K 0.03534417 0.087027854 0.716297159 -0.202715223 -0.800176198 1.667397239 FBgn0001649 l(1)ds1 lethal (1) discs small 1 http://flybase.net/reports/FBgn0001649.html gene l(1)d.sml.-1 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030511 CG11158 http://flybase.net/reports/FBgn0030511.html protein_coding_gene "IPR023186=Inosine/uridine-preferring nucleoside hydrolase, IPR001910=Inosine/uridine-preferring nucleoside hydrolase domain" CG11158 16-Dec-15 2015_12 "ENSDARG00000042124(si:dkey-4e7.3),ENSDARG00000056203(si:dkey-98p3.7)" YDR400W(URH1) "WBGene00012834(Y43F8C.13),WBGene00017436(F13H8.3)" "ENSXETG00000000637(BC090126.1),ENSXETG00000019416(TGas057p14.1)" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0019881 anon-69Ab anon-69Ab http://flybase.net/reports/FBgn0019881.html gene 16-Dec-15 2015_12 " larval stage&& adult stage , embryonic stage && larval stage && adult stage " FBgn0016952 tilI touch insensitive larva I http://flybase.net/reports/FBgn0016952.html gene line 411 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0085775 CR40847 http://flybase.net/reports/FBgn0085775.html FBan0040847 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0002483 l(3)SG42 lethal (3) SG42 http://flybase.net/reports/FBgn0002483.html FBgn0004724 gene "l(3)B4, l(3)ds4" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0267119 CR45559 http://flybase.net/reports/FBgn0267119.html non_protein_coding_gene CR45559 16-Dec-15 2015_12 FBgn0001855 l(1)tsUC34 lethal (1) tsUC34 http://flybase.net/reports/FBgn0001855.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0002497 l(3)SG58 lethal (3) SG58 http://flybase.net/reports/FBgn0002497.html FBgn0004727 gene "l(3)dsl-7, l(3)dsl7, l(3)A7, l(3)IIb1, SG58" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0039098 GILT3 Gamma-interferon-inducible lysosomal thiol reductase 3 http://flybase.net/reports/FBgn0039098.html protein_coding_gene 0015036=disulfide oxidoreductase activity 0055114=oxidation-reduction process "CG13822, Gamma-interferon-inducible lysosomal thiol reductase, GILT" IPR004911=Gamma interferon inducible lysosomal thiol reductase GILT CG13822 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum DRSC14672 I 2.339614071 0.20070092 0.752826588 -0.440910585 0.384792701 -0.216951976 FBgn0267273 CR45709 http://flybase.net/reports/FBgn0267273.html non_protein_coding_gene CR45709 16-Dec-15 2015_12 FBgn0036476 sstn stepping stone http://flybase.net/reports/FBgn0036476.html protein_coding_gene "1903729=regulation of plasma membrane organization, 0051493=regulation of cytoskeleton organization" "0005813=centrosome, 0032154=cleavage furrow" CG6945 CG6945 16-Dec-15 2015_12 "long lived,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266276 CR44961 http://flybase.net/reports/FBgn0266276.html non_protein_coding_gene CR44961 16-Dec-15 2015_12 FBgn0267307 CR45743 http://flybase.net/reports/FBgn0267307.html non_protein_coding_gene CR45743 16-Dec-15 2015_12 FBgn0052765 CR33069 http://flybase.net/reports/FBgn0052765.html non_protein_coding_gene CG32765 16-Dec-15 2015_12 FBgn0030721 CG12698 http://flybase.net/reports/FBgn0030721.html protein_coding_gene "IPR014710=RmlC-like jelly roll fold, IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain" CG12698 16-Dec-15 2015_12 ENSMUSG00000038085 ENSG00000149646(C20orf152) "viable,fertile" FBgn0259210 prom prominin http://flybase.net/reports/FBgn0259210.html "FBgn0027659, FBgn0050164, FBgn0050165, FBgn0050166" protein_coding_gene 0042052=rhabdomere development "0016021=integral component of membrane, 0035996=rhabdomere microvillus" "eyes closed, CG42310, Prominin, CG30165, CG30164, eyc, CG30166, CG4556" IPR008795=Prominin CG42310 16-Dec-15 2015_12 ENSG00000155066(PROM2) FBgn0024948 N::sev N::sev http://flybase.net/reports/FBgn0024948.html FBgn0024966 engineered_fusion_gene 16-Dec-15 2015_12 FBgn0040193 l(1)G0184 lethal (1) G0184 http://flybase.net/reports/FBgn0040193.html gene 16-Dec-15 2015_12 "lethal,recessive" "larva,pupa" FBgn0005345 Salmon Salmon http://flybase.net/reports/FBgn0005345.html gene Sa 16-Dec-15 2015_12 "eye color defective,dominant,visible,lethal,recessive" pigment cell FBgn0011258 ms(3)73D male sterile (3) 73D http://flybase.net/reports/FBgn0011258.html gene 0007286=spermatid development 16-Dec-15 2015_12 male sterile FBgn0019671 mor(1)8 mortality gene (1)8 http://flybase.net/reports/FBgn0019671.html gene 16-Dec-15 2015_12 short lived FBgn0262583 CG43123 http://flybase.net/reports/FBgn0262583.html protein_coding_gene chr2R_3290447_3291368.0 CG43123 16-Dec-15 2015_12 FBgn0041100 park parkin http://flybase.net/reports/FBgn0041100.html FBgn0037054 protein_coding_gene "0008270=zinc ion binding, 0061630=ubiquitin protein ligase activity, 0031624=ubiquitin conjugating enzyme binding" "0000266=mitochondrial fission, 0000422=mitochondrion degradation, 0007005=mitochondrion organization, 0000209=protein polyubiquitination, 0051865=protein autoubiquitination, 0010637=negative regulation of mitochondrial fusion, 0006979=response to oxidative stress, 0010821=regulation of mitochondrion organization, 0016567=protein ubiquitination, 0048477=oogenesis, 0007283=spermatogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0090141=positive regulation of mitochondrial fission, 0070050=neuron cellular homeostasis, 1900407=regulation of cellular response to oxidative stress, 0008344=adult locomotory behavior, 0046329=negative regulation of JNK cascade, 0055069=zinc ion homeostasis, 0030382=sperm mitochondrion organization" "0005739=mitochondrion, 0005829=cytosol, 0005737=cytoplasm" "PK, SD01679, Parkin, dParkin, Park, D-parkin, Dpark, dpk, AAN12155.1, parkin, dparkin, pk, CG10523" "IPR029071=Ubiquitin-related domain, IPR002867=IBR domain, IPR000626=Ubiquitin domain, IPR003977=E3 ubiquitin-protein ligase parkin, IPR031127=E3 ubiquitin ligase RBR family, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019956=Ubiquitin" CG10523 16-Dec-15 2015_12 ENSDARG00000021555(park2) WBGene00003967(pdr-1) ENSMUSG00000023826(Park2) ENSG00000185345(PARK2) adult stage head

"visible,locomotor behavior defective,short lived,body size defective,female sterile,partially lethal - majority die,some die during pupal stage,viable,fertile,gravitaxis defective,neuroanatomy defective,progressive,chemical sensitive,locomotor rhythm defective,decreased cell death,male sterile,flightless,recessive,flight defective,cold sensitive,small body,decreased cell size,decreased cell number,hypoactive,jumping defective,sterile,developmental rate defective,increased cell death,drug conditional,smell perception defective,long lived,nutrition conditional,chemical conditional,oxidative stress response defective,courtship behavior defective,male,female fertile" "nurse cell,oocyte,egg,wing,mitochondrion,egg chamber,ovary,adult heart,cardial cell,mitochondriontin.CëÓ4,dopaminergic PPL1 neuron,progressive,dopaminergic PAM neuron,dorsomedial neurosecretory cell,adult somatic muscle,indirect flight muscle,adult thorax,Nebenkern,myofibril & skeletal muscle of thorax,mitochondrion & skeletal muscle of thorax,Nebenkern derivative,follicle cell,dopaminergic neuron,indirect flight muscle & mitochondrion,indirect flight muscle & nuclear membrane,mitochondrionPc-MK),myofibrilPc-MK),neuron,flight muscle,spermatid,spermatid axoneme,elongation stage spermatid,individualization stage spermatid,mitochondrial crista,adult heart chamber,mesothoracic cleft,ectopic,mitochondrion & dorso-lateral dopaminergic neuronple.PF,eye" FBgn0035904 GstO3 Glutathione S transferase O3 http://flybase.net/reports/FBgn0035904.html protein_coding_gene "0016782=transferase activity, transferring sulfur-containing groups, 0045174=glutathione dehydrogenase (ascorbate) activity, 0004364=glutathione transferase activity, 0004734=pyrimidodiazepine synthase activity" 0006749=glutathione metabolic process 0005737=cytoplasm "glutathione transferase, T14, GSTO3, CG6776" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR005442=Glutathione S-transferase, omega-class" CG6776 16-Dec-15 2015_12 "ENSDARG00000022183(zgc:92254),ENSDARG00000033285(zgc:101897)" "WBGene00019636(gsto-3),WBGene00001792(gst-44),WBGene00016204(gsto-1)" "ENSXETG00000026602(TEgg023j21.1),ENSXETG00000026601(BC087558.1),ENSXETG00000016907()" "ENSMUSG00000025068(Gsto1),ENSMUSG00000025069(Gsto2)" "ENSG00000148834(GSTO1),ENSG00000065621(GSTO2)" "viable,fertile" FBgn0027784 Prp18 Prp18 http://flybase.net/reports/FBgn0027784.html protein_coding_gene 0008266=poly(U) RNA binding "0000398=mRNA splicing, via spliceosome" 0005681=spliceosomal complex "CG6011, prp18" "IPR014906=Pre-mRNA processing factor 4 (PRP4)-like, IPR003648=Splicing factor motif, IPR004098=Prp18" CG6011 16-Dec-15 2015_12 ENSDARG00000058306(prpf18) YGR006W(PRP18) WBGene00009320(F32B6.3) ENSXETG00000024057(PRPF18) ENSMUSG00000039449(Prpf18) ENSG00000165630(PRPF18) "viable,fertile" DRSC16802 I 1.110299876 1.85196 0.525874934 0.831491582 -0.559329725 0.124875137 FBgn0000330 cm carmine http://flybase.net/reports/FBgn0000330.html "FBgn0020512, FBgn0024949" protein_coding_gene 0008565=protein transporter activity "0006887=exocytosis, 0006901=vesicle coating, 0016183=synaptic vesicle coating, 0006897=endocytosis, 0006886=intracellular protein transport, 0007220=Notch receptor processing, 0022008=neurogenesis, 0006727=ommochrome biosynthetic process, 0046907=intracellular transport, 0007040=lysosome organization, 0007269=neurotransmitter secretion, 0008340=determination of adult lifespan" "0030123=AP-3 adaptor complex, 0008021=synaptic vesicle, 0030131=clathrin adaptor complex, 0030135=coated vesicle" "AP3mu3, Dmu3, AP-3, l(1)VEM119, apm3, AP-3mu, mu3, Mu3, cg3035, CG3035, Adaptor Protein complex 3, mu subunit, ap-3, CG32731, Carmine" "IPR028565=Mu homology domain, IPR018240=Clathrin adaptor, mu subunit, conserved site, IPR001392=Clathrin adaptor, mu subunit, IPR011012=Longin-like domain" CG3035 16-Dec-15 2015_12 "ENSDARG00000016128(ap3m2),ENSDARG00000029928(ap3m1)" WBGene00000164(apm-3) ENSXETG00000016796(ap3m2) "ENSMUSG00000021824(Ap3m1),ENSMUSG00000031539(Ap3m2)" "ENSG00000070718(AP3M2),ENSG00000185009(AP3M1)" embryonic stage -- adult stage "viable,fertile,visible,recessive,eye color defective,short lived,male,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective" "pigment cell,secondary pigment cell pigment granule,tertiary pigment cell pigment granule,rhabdomere,Malpighian tubule,ommatidium,photoreceptor cell,wing,eye,ganglion mother cell,mesothoracic tergum" FBgn0053278 CG33278 http://flybase.net/reports/FBgn0053278.html FBgn0035784 protein_coding_gene "CG18656, cg18656" CG33278 16-Dec-15 2015_12 viable DRSC10336 K 0.163230259 0.058415107 -0.430984239 0.122365481 1.454229252 1.699505021 FBgn0065377 l(2)SH1673 lethal (2) SH1673 http://flybase.net/reports/FBgn0065377.html gene l(2)SH2 1673 16-Dec-15 2015_12 "lethal,recessive" FBgn0011872 tRNA:G3:57BCb transfer RNA:gly3:57BCb http://flybase.net/reports/FBgn0011872.html "FBgn0003783, FBgn0050210, FBgn0060228" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033462=GGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna47-GlyGCC, tRNA:G:GCC:AE002575-a, CR30210, tRNA[Gly-GCC], AE002575.trna3-GlyGCC, tRNA:gly3:57BCb" CR30210 16-Dec-15 2015_12 FBgn0015411 l(1)14ABb lethal (1) 14ABb http://flybase.net/reports/FBgn0015411.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026667 l(1)G0132 lethal (1) G0132 http://flybase.net/reports/FBgn0026667.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0027268 l(1)G0212 lethal (1) G0212 http://flybase.net/reports/FBgn0027268.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0020246 tss toothless http://flybase.net/reports/FBgn0020246.html gene 16-Dec-15 2015_12 FBgn0040651 CG15458 http://flybase.net/reports/FBgn0040651.html protein_coding_gene CG15458 16-Dec-15 2015_12 viable FBgn0036083 Ir67b Ionotropic receptor 67b http://flybase.net/reports/FBgn0036083.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 67b, IR67b, DmelIR67b, CG12303" CG12303 16-Dec-15 2015_12 viable FBgn0035793 CG7546 http://flybase.net/reports/FBgn0035793.html FBgn0025951 protein_coding_gene "anon-EST:Liang-2.45, clone 2.45" "IPR029071=Ubiquitin-related domain, IPR019954=Ubiquitin conserved site, IPR021925=Protein of unknown function DUF3538, IPR000626=Ubiquitin domain" CG7546 16-Dec-15 2015_12 "ENSDARG00000035900,ENSDARG00000003215" ENSXETG00000002500(BAT3) ENSMUSG00000024392(Bat3) "ENSG00000204463(BAG6),ENSG00000206313,ENSG00000096155" "viable,fertile,visible,body color defective" mesothoracic tergum FBgn0028041 l(3)S099013 lethal (3) S099013 http://flybase.net/reports/FBgn0028041.html gene "unnamed, 0990/13, 1002/02" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001443 l(1)7Ce lethal (1) 7Ce http://flybase.net/reports/FBgn0001443.html gene 16-Dec-15 2015_12 lethal FBgn0019955 Nrt::Tmar\AChE Nrt::Tmar\AChE http://flybase.net/reports/FBgn0019955.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0022091 l(2)k07308 lethal (2) k07308 http://flybase.net/reports/FBgn0022091.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259484 smo::Mmmm\EB2 http://flybase.net/reports/FBgn0259484.html engineered_fusion_gene EB2-SMO 16-Dec-15 2015_12 FBgn0042127 CG18789 http://flybase.net/reports/FBgn0042127.html protein_coding_gene 0046872=metal ion binding "IPR000571=Zinc finger, CCCH-type" CG18789 16-Dec-15 2015_12 ENSXETG00000005935(nupl2) ENSG00000136243(NUPL2) FBgn0262828 CR43199 http://flybase.net/reports/FBgn0262828.html non_protein_coding_gene "noncoding_22394, CG43199" CR43199 16-Dec-15 2015_12 FBgn0028361 l(1)G0140 lethal (1) G0140 http://flybase.net/reports/FBgn0028361.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0044514 l(2)Mai179 lethal (2) Mai179 http://flybase.net/reports/FBgn0044514.html gene Mai179 16-Dec-15 2015_12 "lethal,recessive" FBgn0265338 CR44292 http://flybase.net/reports/FBgn0265338.html non_protein_coding_gene CR44292 16-Dec-15 2015_12 FBgn0065112 p45 p45 http://flybase.net/reports/FBgn0065112.html gene 16-Dec-15 2015_12 FBgn0052520 tRNA:CR32520 transfer RNA:CR32520 http://flybase.net/reports/FBgn0052520.html "FBgn0012015, FBgn0060009" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002620.trna1-TyrGTA, chrX.trna18-TyrGTA, tRNA:tyr1:19F, tRNA:Y:GTA:AE002620-a, tRNA[Tyr][[1gamma]], tRNA:Y1:19F, transfer RNA:tyr1:19F, CR32520" CR32520 16-Dec-15 2015_12 FBgn0002757 mit(1)7 mitotic 7 http://flybase.net/reports/FBgn0002757.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0024938 Ruf Ruf http://flybase.net/reports/FBgn0024938.html gene 16-Dec-15 2015_12 "visible,dominant" "eye,wing,wing vein" FBgn0265482 BG01907 http://flybase.net/reports/FBgn0265482.html gene 16-Dec-15 2015_12 sleep defective FBgn0037570 CG11693 http://flybase.net/reports/FBgn0037570.html protein_coding_gene IPR007999=Protein of unknown function DUF745 CG11693 16-Dec-15 2015_12 viable FBgn0266269 Hto-WP(2)NAW http://flybase.net/reports/FBgn0266269.html gene 16-Dec-15 2015_12 "wing hair,wing" FBgn0015519 nAChRë±3 nicotinic Acetylcholine Receptor ë±3 http://flybase.net/reports/FBgn0015519.html protein_coding_gene "0004889=acetylcholine-activated cation-selective channel activity, 0015464=acetylcholine receptor activity" 0006812=cation transport "0045211=postsynaptic membrane, 0005892=acetylcholine-gated channel complex" "Dalpha3, lincRNA.965, D[a3], Acr7E, nAChR, Drosophila alpha-like subunit 3, CG2302, nACRalpha-7E, nicotinic Acetylcholine Receptor alpha 7E, Da3, nAcRe, alpha3, nAcRalpha-7E" "IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006201=Neurotransmitter-gated ion-channel, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR002394=Nicotinic acetylcholine receptor" CG2302 16-Dec-15 2015_12 "ENSDARG00000057025(chrna2b),ENSDARG00000006602(chrna2a),ENSDARG00000058393(chrna4),ENSDARG00000070724(LOC563696),ENSDARG00000057848,ENSDARG00000054497(LOC568467),ENSDARG00000055559(chrna6)" WBGene00006797(unc-63) ENSXETG00000017553(CHRNA2) "ENSMUSG00000032303(Chrna3),ENSMUSG00000031491(Chrna6),ENSMUSG00000027577(Chrna4),ENSMUSG00000022041(Chrna2)" "ENSG00000101204(CHRNA4),ENSG00000120903(CHRNA2),ENSG00000080644(CHRNA3),ENSG00000147434(CHRNA6)" viable FBgn0002658 mat(2)cell-G maternal effect cellularisation defect G http://flybase.net/reports/FBgn0002658.html gene 0007349=cellularization "mat(2)cellQE1, QE1, cell-QE1" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0005706 l(1)TK109 lethal (1) TK109 http://flybase.net/reports/FBgn0005706.html gene l109 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" eye FBgn0027503 CG11970 http://flybase.net/reports/FBgn0027503.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0031011=Ino80 complex, 0005634=nucleus" BcDNA:LD23876 "IPR024867=Nuclear factor related to kappa-B-binding protein, IPR025220=NFRKB winged helix-like domain" CG11970 16-Dec-15 2015_12 ENSXETG00000004078(nfrkb) ENSMUSG00000042185(Nfrkb) ENSG00000170322(NFRKB) FBgn0030716 CG9170 http://flybase.net/reports/FBgn0030716.html FBgn0044658 protein_coding_gene anon-WO0140519.214 IPR001202=WW domain CG9170 16-Dec-15 2015_12 ENSG00000110274(CEP164) viable FBgn0013717 not non-stop http://flybase.net/reports/FBgn0013717.html "FBgn0010766, FBgn0011415, FBgn0063787" protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding, 0004843=ubiquitin-specific protease activity" "0006355=regulation of transcription, DNA-templated, 0021782=glial cell development, 0006325=chromatin organization, 0007411=axon guidance, 0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0008347=glial cell migration, 0016578=histone deubiquitination, 0007412=axon target recognition" "0005634=nucleus, 0000124=SAGA complex, 0071819=DUBm complex" "NOT, Nonstop, anon-WO0257455.9, Non-stop, USP22, CG4166, nonstop, Not, l(3)02069, Upb8, i155, Q9VVR1, l(3)j9A6, UBP8" "IPR001607=Zinc finger, UBP-type, IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR015880=Zinc finger, C2H2-like" CG4166 16-Dec-15 2015_12 ENSDARG00000040407(usp22) YMR223W(UBP8) ENSXETG00000006051() "ENSMUSG00000042506(Usp22),ENSMUSG00000046269(Usp27x),ENSMUSG00000067215(Usp51)" "ENSG00000124422(USP22),ENSG00000180991,ENSG00000185295" "suppressor of variegation,neuroanatomy defective,somatic clone,lethal,recessive,enhancer of variegation,dominant,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal - all die before end of prepupal stage,partially,some die during prepupal stage,planar polarity defective,visible,heat sensitive" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor,larval inner optic anlage,larval outer optic anlage,axon & photoreceptor cell R2,axon & photoreceptor cell R3,axon & photoreceptor cell R4,axon & photoreceptor cell R5,photoreceptor cell & axon,lamina,lamina plexus,medulla,marginal glial cell,epithelial glial cell,medulla neuropil glial cell,photoreceptor cell & axonW4),ommatidium,somatic clone,eye photoreceptor cell,wing hair,wing,wing margin bristle,scutellar bristle,supernumerary" FBgn0010245 Mst77F-ë¬Y3 Mst77F pseudogene on Y 3 http://flybase.net/reports/FBgn0010245.html pseudogene_attribute "18c, Mst77-Psi3" 16-Dec-15 2015_12 FBgn0004214 l(3)84Fb lethal (3) 84Fb http://flybase.net/reports/FBgn0004214.html gene 16-Dec-15 2015_12 lethal FBgn0260237 CG42511 http://flybase.net/reports/FBgn0260237.html protein_coding_gene 0042384=cilium assembly 0034464=BBSome BBIP1 IPR028233=Cilia BBSome complex subunit 10 CG42511 16-Dec-15 2015_12 FBgn0015491 l(3)65ACa lethal (3) 65ACa http://flybase.net/reports/FBgn0015491.html gene "I, Distal W5.4 Group I" 16-Dec-15 2015_12 "lethal,recessive" FBgn0031367 c-cup calcutta cup http://flybase.net/reports/FBgn0031367.html protein_coding_gene 0007140=male meiosis "calcutta-cup, CG15623" IPR001199=Cytochrome b5-like heme/steroid binding domain CG15623 16-Dec-15 2015_12 viable FBgn0029603 CG14053 http://flybase.net/reports/FBgn0029603.html FBgn0063349 protein_coding_gene BcDNA:AT10359 CG14053 16-Dec-15 2015_12 FBgn0061076 l(3)S015102b lethal (3) S015102b http://flybase.net/reports/FBgn0061076.html gene 0151/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0060949 l(3)S037703 lethal (3) S037703 http://flybase.net/reports/FBgn0060949.html gene 0377/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0264638 creeper creeper http://flybase.net/reports/FBgn0264638.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0016823 l(1)MZ10 lethal (1) MZ10 http://flybase.net/reports/FBgn0016823.html gene M10 16-Dec-15 2015_12 "lethal,recessive" FBgn0037405 CG1077 http://flybase.net/reports/FBgn0037405.html FBgn0000091 protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion "anon-f, unnamed" IPR002350=Kazal domain CG1077 16-Dec-15 2015_12 "viable,fertile" FBgn0086361 alph alphabet http://flybase.net/reports/FBgn0086361.html "FBgn0084988, FBgn0043570, FBgn0039672" protein_coding_gene "0016791=phosphatase activity, 0000287=magnesium ion binding, 0004722=protein serine/threonine phosphatase activity, 0030145=manganese ion binding" "0008340=determination of adult lifespan, 0046580=negative regulation of Ras protein signal transduction, 0006470=protein dephosphorylation, 0070303=negative regulation of stress-activated protein kinase signaling cascade, 0001745=compound eye morphogenesis, 0007391=dorsal closure, 0032873=negative regulation of stress-activated MAPK cascade, 0010225=response to UV-C, 0045678=positive regulation of R7 cell differentiation, 0046329=negative regulation of JNK cascade, 1901562=response to paraquat, 0006979=response to oxidative stress, 0016311=dephosphorylation, 0046529=imaginal disc fusion, thorax closure, 0007476=imaginal disc-derived wing morphogenesis, 1900744=regulation of p38MAPK cascade, 0043407=negative regulation of MAP kinase activity, 0070373=negative regulation of ERK1 and ERK2 cascade, 0000278=mitotic cell cycle" "PP2Cb, SK3-1, alphabet, CG1906, pp2c99B" "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C, IPR012911=Protein serine/threonine phosphatase 2C, C-terminal, IPR000222=PPM-type phosphatase, divalent cation binding" CG1906 16-Dec-15 2015_12 "ENSDARG00000011496(ppm1a),ENSDARG00000001888(pp2cb),ENSDARG00000032155(pp2ca2),ENSDARG00000043250(pp2ca1)" WBGene00006460(tag-93) "ENSXETG00000002746(ppm1b),ENSXETG00000016952(ppm1a)" "ENSMUSG00000061130(Ppm1b),ENSMUSG00000021096(Ppm1a)" "ENSG00000138032(PPM1B),ENSG00000100614(PPM1A)" DRSC15398 K 0.797108569 0.918843224 1.337706125 0.732744976 0.303647055 1.518854699 FBgn0040929 CG12659 http://flybase.net/reports/FBgn0040929.html protein_coding_gene "0006338=chromatin remodeling, 0006355=regulation of transcription, DNA-templated" 0031011=Ino80 complex "IPR013272=Vps72/YL1, C-terminal, IPR029525=INO80 complex, subunit Ies6" CG12659 16-Dec-15 2015_12 "viable,fertile" FBgn0261929 5-HT2B 5-hydroxytryptamine (serotonin) receptor 2B http://flybase.net/reports/FBgn0261929.html "FBgn0037599, FBgn0046496, FBgn0046497, FBgn0037600, FBgn0046494, FBgn0046495" protein_coding_gene "0004993=serotonin receptor activity, 0008227=G-protein coupled amine receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007210=serotonin receptor signaling pathway" "0016021=integral component of membrane, 0005886=plasma membrane" "anon-WO0170980.95, anon-WO0170980.98, CG8007, anon-WO0170980.94, anon-WO0170980.97, CG7994, CG42796" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG42796 16-Dec-15 2015_12 FBgn0043558 Su(roDOM)1993 Su(roDOM)1993 http://flybase.net/reports/FBgn0043558.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive,visible" "eye,wing" FBgn0259735 CG42389 http://flybase.net/reports/FBgn0259735.html "FBgn0032589, FBgn0051738, FBgn0026005, FBgn0032591, FBgn0032592" protein_coding_gene 0005886=plasma membrane "CG13261, CG4668, CG13260, CG31738, clone 1.16, CT15049, CT15043, anon-EST:Liang-1.16" "IPR013783=Immunoglobulin-like fold, IPR003961=Fibronectin type III" CG42389 16-Dec-15 2015_12 "ENSXETG00000013335(FNDC3A),ENSXETG00000010132(),ENSXETG00000023615(FNDC3B)" "ENSMUSG00000033487(Fndc3a),ENSMUSG00000039286(Fndc3b),ENSMUSG00000033737(Fndc3c1)" "ENSG00000102531(FNDC3A),ENSG00000075420(FNDC3B)" FBgn0082831 pps protein partner of snf http://flybase.net/reports/FBgn0082831.html FBgn0038041 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding, 0016817=hydrolase activity, acting on acid anhydrides, 0005515=protein binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0006355=regulation of transcription, DNA-templated" "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex, 0000790=nuclear chromatin" "SNFs Protein Partner, SPP, FBgn0082831, CG6525, protein partner of sans-fille, Spp, spp" "IPR019787=Zinc finger, PHD-finger, IPR012921=Spen paralogue and orthologue SPOC, C-terminal, IPR001965=Zinc finger, PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR003618=Transcription elongation factor S-II, central domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR006576=BRK domain, IPR019786=Zinc finger, PHD-type, conserved site, IPR017890=Transcription elongation factor S-IIM" CG6525 16-Dec-15 2015_12 ENSMUSG00000048874(Phf3) female sterile ovary DRSC16057 E 0.049398803 -0.169651704 0.886425959 -1.914224849 0.991188091 1.118335948 FBgn0053376 5SrRNA:CR33376 5SrRNA:CR33376 http://flybase.net/reports/FBgn0053376.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33376 CR33376 16-Dec-15 2015_12 FBgn0030206 CG2889 http://flybase.net/reports/FBgn0030206.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2" CG2889 16-Dec-15 2015_12 "ENSG00000158805(ZNF276),ENSG00000161914(ZNF653)" "viable,fertile" FBgn0266506 s-349 http://flybase.net/reports/FBgn0266506.html gene 16-Dec-15 2015_12 FBgn0010549 l(2)03659 lethal (2) 03659 http://flybase.net/reports/FBgn0010549.html "FBgn0016971, FBgn0033406, FBgn0033407" protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" "0007275=multicellular organismal development, 0055085=transmembrane transport, 0006810=transport" "0043190=ATP-binding cassette (ABC) transporter complex, 0016021=integral component of membrane" "hspr, A, Dme_CG8799, CG8799, Hsp related, CG11803" "IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site" CG8799 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) "lethal,recessive,partially lethal - majority live,sterile,viable" "head bristle,macrochaeta & thorax03659EMS93),scutellar bristle,wing,macrochaeta & thorax03659EMS5)" FBgn0086683 Spf45 Spf45 http://flybase.net/reports/FBgn0086683.html "FBgn0040024, FBgn0062542" protein_coding_gene "0003676=nucleic acid binding, 0005515=protein binding, 0000166=nucleotide binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0001745=compound eye morphogenesis, 0006281=DNA repair" "0005681=spliceosomal complex, 0071011=precatalytic spliceosome" "RBM17, CG17540, dSPF45, dRBM17, SPF45, RNA binding motif protein 1, spf-45, spf45" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR016967=Splicing factor, SPF45, IPR000467=G-patch domain" CG17540 16-Dec-15 2015_12 ENSDARG00000031346(rbm17) WBGene00010233(F58B3.7) ENSXETG00000018123(rbm17) ENSMUSG00000037197(Rbm17) ENSG00000134453(RBM17) "viable,visible,fertile,DNA repair defective,chemical sensitive" trichogen cell FBgn0000948 fs(2)A18 female sterile (2) A18 http://flybase.net/reports/FBgn0000948.html gene 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oocyte" FBgn0002886 mus112 mutagen-sensitive 112 http://flybase.net/reports/FBgn0002886.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0267565 CR45905 http://flybase.net/reports/FBgn0267565.html non_protein_coding_gene CR45905 16-Dec-15 2015_12 FBgn0029075 l(1)G0141 lethal (1) G0141 http://flybase.net/reports/FBgn0029075.html gene 16-Dec-15 2015_12 "lethal,male sterile,partially lethal - majority die,recessive" chaeta FBgn0263767 CR43684 http://flybase.net/reports/FBgn0263767.html non_protein_coding_gene CR43684 16-Dec-15 2015_12 FBgn0065439 l(2)SH1464 lethal (2) SH1464 http://flybase.net/reports/FBgn0065439.html gene l(2)SH2 1464 16-Dec-15 2015_12 "lethal,recessive" FBgn0060721 l(3)S068601b lethal (3) S068601b http://flybase.net/reports/FBgn0060721.html gene 0686/01 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085250 CG34221 http://flybase.net/reports/FBgn0085250.html protein_coding_gene CG34221 16-Dec-15 2015_12 FBgn0033836 CG18278 http://flybase.net/reports/FBgn0033836.html FBgn0050059 protein_coding_gene 0008449=N-acetylglucosamine-6-sulfatase activity "0030203=glycosaminoglycan metabolic process, 0006044=N-acetylglucosamine metabolic process" 0005764=lysosome "IPR017850=Alkaline-phosphatase-like, core domain, IPR024607=Sulfatase, conserved site, IPR012251=N-acetylglucosamine-6-sulfatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR000917=Sulfatase" CG18278 16-Dec-15 2015_12 ENSXETG00000007318(GNS) ENSMUSG00000034707(Gns) ENSG00000135677(GNS) FBgn0037627 CG13318 http://flybase.net/reports/FBgn0037627.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "Dmel_CG13318, c-SPH101, SPH101" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG13318 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" "viable,fertile" FBgn0021972 l(2)k10001 lethal (2) k10001 http://flybase.net/reports/FBgn0021972.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053087 LRP1 LDL receptor protein 1 http://flybase.net/reports/FBgn0053087.html "FBgn0033276, FBgn0050368" protein_coding_gene "0005041=low-density lipoprotein receptor activity, 0015248=sterol transporter activity, 0005509=calcium ion binding" "0042303=molting cycle, 0015918=sterol transport" 0005829=cytosol "CT9297, LDL receptor protein, CG33087, LDLR-like, LRP1, CG8706, LDLR, lrp1, LDL-receptor-related protein 1, Dm CG33087, CG30368, LDL-receptor-related protein" "IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site, IPR031070=Low-density lipoprotein receptor-related protein, IPR000033=LDLR class B repeat, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR011042=Six-bladed beta-propeller, TolB-like, IPR013032=EGF-like, conserved site, IPR001881=EGF-like calcium-binding domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG33087 16-Dec-15 2015_12 "ENSDARG00000029146,ENSDARG00000061517(LOC559293)" WBGene00003072(lrp-2) "ENSMUSG00000040249(Lrp1),ENSMUSG00000049252(Lrp1b)" "ENSG00000123384(LRP1),ENSG00000168702(LRP1B)" "viable,fertile" FBgn0085208 CG34179 http://flybase.net/reports/FBgn0085208.html protein_coding_gene CG34179 16-Dec-15 2015_12 FBgn0033137 Tsp42Ep Tetraspanin 42Ep http://flybase.net/reports/FBgn0033137.html protein_coding_gene 0016021=integral component of membrane "tetraspanin 42E, CG4471, Dm.Tsp42Ep" "IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG4471 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell DRSC06871 E -0.814941855 0.392695217 1.690089221 -0.425865251 0.511134948 0.403554274 FBgn0260472 CG13673 http://flybase.net/reports/FBgn0260472.html FBgn0040831 protein_coding_gene 16-Dec-15 2015_12 FBgn0265953 CR44740 http://flybase.net/reports/FBgn0265953.html non_protein_coding_gene CR44740 16-Dec-15 2015_12 FBgn0037890 CG17734 http://flybase.net/reports/FBgn0037890.html FBgn0063654 protein_coding_gene 0048149=behavioral response to ethanol BcDNA:RH54117 "IPR007667=Hypoxia induced protein, domain" CG17734 16-Dec-15 2015_12 ENSDARG00000022303(hig1) "ENSXETG00000006171(hig1a),ENSXETG00000025166(hig1b),ENSXETG00000003392(HIGD1B)" "ENSMUSG00000038412(Higd1a),ENSMUSG00000044330(Gm9790),ENSMUSG00000020928(Higd1b)" "ENSG00000181061(HIGD1A),ENSG00000214511(HIGD1C),ENSG00000131097(HIGD1B)" "viable,fertile,hyperactive,conditional,chemical resistant" FBgn0260598 2L2845 http://flybase.net/reports/FBgn0260598.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0015883 anon-64Be anon-64Be http://flybase.net/reports/FBgn0015883.html gene 16-Dec-15 2015_12 adult stage adult head

FBgn0065419 l(2)SH1529 lethal (2) SH1529 http://flybase.net/reports/FBgn0065419.html gene l(2)SH2 1529 16-Dec-15 2015_12 "lethal,recessive" FBgn0004902 Lrr70C Leucine-repeat-protein-70C http://flybase.net/reports/FBgn0004902.html gene 0005886=plasma membrane 16-Dec-15 2015_12 FBgn0030451 CG15717 http://flybase.net/reports/FBgn0030451.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process "IPR009961=Protein of unknown function DUF1487, IPR016161=Aldehyde/histidinol dehydrogenase" CG15717 16-Dec-15 2015_12 viable FBgn0027128 l(3)ESH2 lethal (3) ESH2 http://flybase.net/reports/FBgn0027128.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0263947 BG00757 http://flybase.net/reports/FBgn0263947.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0266209 CR44904 http://flybase.net/reports/FBgn0266209.html non_protein_coding_gene CR44904 16-Dec-15 2015_12 FBgn0060803 l(3)SzB90Cl lethal (3) SzB90Cl http://flybase.net/reports/FBgn0060803.html gene "0569/16, l(3)S056916b" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267115 CR45555 http://flybase.net/reports/FBgn0267115.html non_protein_coding_gene CR45555 16-Dec-15 2015_12 FBgn0020801 ms(3)D185 ms(3)D185 http://flybase.net/reports/FBgn0020801.html gene 3-D185 16-Dec-15 2015_12 "male sterile,recessive,chemical sensitive" FBgn0002394 l(3)93Fa lethal (3) 93Fa http://flybase.net/reports/FBgn0002394.html gene "er17, l(3)er17" 16-Dec-15 2015_12 "lethal,recessive" FBgn0060615 l(3)S089814b lethal (3) S089814b http://flybase.net/reports/FBgn0060615.html gene 0898/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0263543 mir-4979 mir-4979 stem loop http://flybase.net/reports/FBgn0263543.html miRNA_gene "CR43528, dme-mir-4979" CR43528 16-Dec-15 2015_12 FBgn0045056 fs(1)186 female sterile (1) 186 http://flybase.net/reports/FBgn0045056.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile follicle cell FBgn0052833 CG32833 http://flybase.net/reports/FBgn0052833.html "FBgn0034806, FBgn0064968" protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0032504=multicellular organism reproduction" 0005615=extracellular space "CG30331, SPH196, CG9898, BcDNA:GH11992" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG32833 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0010836 l(3)04220 lethal (3) 04220 http://flybase.net/reports/FBgn0010836.html FBgn0011435 gene l(3)j11E7 16-Dec-15 2015_12 "lethal,recessive" FBgn0262728 Pal2 Peptidyl-ë±-hydroxyglycine-ë±-amidating lyase 2 http://flybase.net/reports/FBgn0262728.html "FBgn0069355, FBgn0020623, FBgn0034890, FBgn0045948" protein_coding_gene 0004598=peptidylamidoglycolate lyase activity 0044237=cellular metabolic process 0005576=extracellular region "dPAL2, PAL, Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase, Pal2, Pal, CG5472, PAL2, anon-WO0149856.5" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR001258=NHL repeat, IPR013017=NHL repeat, subgroup" CG5472 16-Dec-15 2015_12 ENSDARG00000069714 WBGene00017671(F21F3.1) ENSXETG00000016032(NHLRC3) ENSMUSG00000042997(Nhlrc3) FBgn0031498 CG17260 http://flybase.net/reports/FBgn0031498.html protein_coding_gene 0008270=zinc ion binding "IPR006575=RWD domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR001841=Zinc finger, RING-type" CG17260 16-Dec-15 2015_12 FBgn0261393 ë±-Est5 ë±-Esterase-5 http://flybase.net/reports/FBgn0261393.html "FBgn0015573, FBgn0000593" protein_coding_gene 0052689=carboxylic ester hydrolase activity "CG1089, aE5, Est-9, D, unnamed, Esterase C, ESTC, alphaE5, alpha-Est5, DmalphaE5, fragment D, EST9, Est-c, alpha-Esterase-5, EST-C, Est-C, esterase-C" "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold" CG1089 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" FBgn0027110 ms(2)RK2 ms(2)RK2 http://flybase.net/reports/FBgn0027110.html gene unnamed 16-Dec-15 2015_12 "male sterile,recessive" FBgn0015808 ScpX Sterol carrier protein X-related thiolase http://flybase.net/reports/FBgn0015808.html FBgn0032716 protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups, 0005548=phospholipid transporter activity" "0008152=metabolic process, 0015914=phospholipid transport" "0005777=peroxisome, 0005739=mitochondrion, 0005811=lipid particle, 0005737=cytoplasm" "sterol carrier protein X-related thiolase, CG17320, sterol carrier protein x" "IPR016039=Thiolase-like, IPR003033=SCP2 sterol-binding domain, IPR020615=Thiolase, acyl-enzyme intermediate active site, IPR020616=Thiolase, N-terminal, IPR020613=Thiolase, conserved site, IPR020617=Thiolase, C-terminal, IPR002155=Thiolase" CG17320 16-Dec-15 2015_12 ENSDARG00000012194(scp2) WBGene00013284(daf-22) ENSXETG00000024490(Q5EBE0_XENTR) ENSMUSG00000028603(Scp2) ENSG00000116171(SCP2) viable FBgn0058469 CR40469 http://flybase.net/reports/FBgn0058469.html non_protein_coding_gene CR40469 16-Dec-15 2015_12 FBgn0022729 l(2)PGM-45 lethal (2) PGM-45 http://flybase.net/reports/FBgn0022729.html gene PGM-45 16-Dec-15 2015_12 "lethal,recessive" FBgn0265872 CR44661 http://flybase.net/reports/FBgn0265872.html non_protein_coding_gene lincRNA.996 CR44661 16-Dec-15 2015_12 FBgn0003605 Su(var)3-14 Suppressor of variegation 3-14 http://flybase.net/reports/FBgn0003605.html gene Su-var(3)14 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0259794 sinah sina homologue http://flybase.net/reports/FBgn0259794.html "FBgn0016062, FBgn0036669, FBgn0044643" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0007423=sensory organ development, 0010498=proteasomal protein catabolic process, 0045676=regulation of R7 cell differentiation, 0006511=ubiquitin-dependent protein catabolic process" 0005634=nucleus "SinaH, Sina-Homologue, CG13030, sina-h, anon-WO0140519.228" "IPR018121=Seven-in-absentia protein, TRAF-like domain, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR013323=SIAH-type domain, IPR004162=E3 ubiquitin-protein ligase SIN-like, IPR008974=TRAF-like, IPR013010=Zinc finger, SIAH-type" CG13030 16-Dec-15 2015_12 DRSC22181 E -0.196175672 -0.162330458 -1.797217815 -0.170535057 1.380275235 0.165849511 FBgn0083962 CG34126 http://flybase.net/reports/FBgn0083962.html "FBan0003805, FBgn0031665, FBgn0051653" protein_coding_gene "CG3805, CG31653, Dm_2L:23546, Dm_2L:23517" "IPR026728=UHRF1-binding protein 1-like, IPR026854=Vacuolar protein sorting-associated protein 13A, N-terminal domain" CG34126 16-Dec-15 2015_12 ENSDARG00000004055(uhrf1bp1l) WBGene00008094(C44H4.4) ENSXETG00000022694(UHRF1BP1L) "ENSMUSG00000019951(Uhrf1bp1l),ENSMUSG00000039512(Uhrf1bp1)" "ENSG00000111647(UHRF1BP1L),ENSG00000065060(UHRF1BP1)" "viable,fertile,visible" trichogen cell FBgn0033508 Obp46a Odorant-binding protein 46a http://flybase.net/reports/FBgn0033508.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG12905, DmelObp46a" CG12905 16-Dec-15 2015_12 viable FBgn0030660 CG8097 http://flybase.net/reports/FBgn0030660.html protein_coding_gene "0004814=arginine-tRNA ligase activity, 0005524=ATP binding" 0006420=arginyl-tRNA aminoacylation "IPR008909=DALR anticodon binding, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding" CG8097 16-Dec-15 2015_12 ENSXETG00000009339(DALRD3) ENSG00000178149(DALRD3) "viable,fertile" FBgn0067320 C75 C75 http://flybase.net/reports/FBgn0067320.html gene 16-Dec-15 2015_12 "visible,lethal,viable" chaeta FBgn0052773 CR32773 http://flybase.net/reports/FBgn0052773.html non_protein_coding_gene CG32773 CR32773 16-Dec-15 2015_12 FBgn0069153 mcl(3)Z3298 mcl(3)Z3298 http://flybase.net/reports/FBgn0069153.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0005709 l(1)TK112 lethal (1) TK112 http://flybase.net/reports/FBgn0005709.html gene l112 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0033168 CG11145 http://flybase.net/reports/FBgn0033168.html FBgn0063721 protein_coding_gene BcDNA:AT20622 CG11145 16-Dec-15 2015_12 viable FBgn0082990 snoRNA:ë¬28S-2263 snoRNA:ë¬28S-2263 http://flybase.net/reports/FBgn0082990.html snoRNA_gene "psi28s-2263, CR34568" CR34568 16-Dec-15 2015_12 FBgn0052364 tut tumorous testis http://flybase.net/reports/FBgn0052364.html FBgn0061735 protein_coding_gene "0003723=RNA binding, 0000166=nucleotide binding" "0098730=male germline stem cell symmetric division, 0017148=negative regulation of translation" 0005737=cytoplasm "anon-WO0118547.705, CG32364" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG32364 16-Dec-15 2015_12 viable FBgn0035012 CG13590 http://flybase.net/reports/FBgn0035012.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG13590 16-Dec-15 2015_12 viable DRSC04226 IE -1.560772141 0.960863464 -1.906118885 -2.422774858 -0.452955198 0.133985831 FBgn0015490 l(2)46Cn lethal (2) 46Cn http://flybase.net/reports/FBgn0015490.html gene "X, Complementation group X" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085703 CG41577 http://flybase.net/reports/FBgn0085703.html FBan0041577 protein_coding_gene 16-Dec-15 2015_12 FBgn0040696 CG18675 http://flybase.net/reports/FBgn0040696.html protein_coding_gene 0048812=neuron projection morphogenesis IPR021298=Protein of unknown function DUF2870 CG18675 16-Dec-15 2015_12 ENSDARG00000035332(c21orf59l) ENSXETG00000009902(C21orf59) ENSMUSG00000022972(1110004E09Rik) ENSG00000159079(C21orf59) "viable,fertile" FBgn0034854 Golgin245 Golgin-245 ortholog (H. sapiens) http://flybase.net/reports/FBgn0034854.html protein_coding_gene "0017137=Rab GTPase binding, 0030306=ADP-ribosylation factor binding, 0042803=protein homodimerization activity" "0000042=protein targeting to Golgi, 0048193=Golgi vesicle transport" "0000138=Golgi trans cisterna, 0005794=Golgi apparatus" "dGolgin-245, dGolgin245, CG3493" IPR000237=GRIP CG3493 16-Dec-15 2015_12 WBGene00010306(F59A2.6) ENSMUSG00000038708(Golga4) ENSG00000144674(GOLGA4) viable FBgn0022975 snRNP105K snRNP105K http://flybase.net/reports/FBgn0022975.html gene "0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus" 105K 16-Dec-15 2015_12 FBgn0262222 mir-971 mir-971 stem loop http://flybase.net/reports/FBgn0262222.html miRNA_gene "dme-mir-971, miR-971, CR42929" CR42929 16-Dec-15 2015_12 "visible,lethal" "eye,wing vein,wing" FBgn0020807 mfs(3)D83 mfs(3)D83 http://flybase.net/reports/FBgn0020807.html gene 3-D83 16-Dec-15 2015_12 "male sterile,recessive,female sterile,chemical sensitive" FBgn0002491 l(3)SG51 lethal (3) SG51 http://flybase.net/reports/FBgn0002491.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0004992 cld cloudy http://flybase.net/reports/FBgn0004992.html gene 16-Dec-15 2015_12 "visible,recessive,female semi-sterile,male sterile" wing FBgn0259439 C607 http://flybase.net/reports/FBgn0259439.html gene 16-Dec-15 2015_12 visible wing FBgn0267721 CR46054 http://flybase.net/reports/FBgn0267721.html non_protein_coding_gene CR46054 16-Dec-15 2015_12 FBgn0267551 CR45891 http://flybase.net/reports/FBgn0267551.html non_protein_coding_gene CR45891 16-Dec-15 2015_12 FBgn0026878 CG4325 http://flybase.net/reports/FBgn0026878.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0016567=protein ubiquitination, 0002805=regulation of antimicrobial peptide biosynthetic process, 0035556=intracellular signal transduction" EG:22E5.12 "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG4325 16-Dec-15 2015_12 ENSDARG00000068612 lethal FBgn0011162 l(1)Q244 lethal (1) Q244 http://flybase.net/reports/FBgn0011162.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0003144 pratf pratfall http://flybase.net/reports/FBgn0003144.html gene 0001700=embryonic development via the syncytial blastoderm prat 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic segment,maternal effect,embryonic/first instar larval cuticle" FBgn0025559 anon-66Fb anon-66Fb http://flybase.net/reports/FBgn0025559.html gene 16-Dec-15 2015_12 FBgn0019830 colt congested-like trachea http://flybase.net/reports/FBgn0019830.html protein_coding_gene "0005215=transporter activity, 0005476=carnitine:acyl carnitine antiporter activity" "0006839=mitochondrial transport, 0006909=phagocytosis, 0003382=epithelial cell morphogenesis, 0035002=liquid clearance, open tracheal system, 0015879=carnitine transport, 0006844=acyl carnitine transport" "0016021=integral component of membrane, 0005743=mitochondrial inner membrane, 0005740=mitochondrial envelope" "CG3057, collapsed trachea" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG3057 16-Dec-15 2015_12 ENSDARG00000071052(si:dkey-150i13.2) YOR100C(CRC1) WBGene00000996(dif-1) ENSXETG00000009331(slc25a20) ENSMUSG00000032602(Slc25a20) ENSG00000178537(SLC25A20) embryonic stage -- adult stage "partially lethal - majority die,recessive,female sterile,poor,lethal,viable" "embryonic/larval tracheal system,wing,wing vein,wing & trichome" FBgn0003436 sma smaller http://flybase.net/reports/FBgn0003436.html gene 16-Dec-15 2015_12 "eye color defective,recessive,visible,viable,fertile" pigment cell FBgn0037398 CG15580 http://flybase.net/reports/FBgn0037398.html protein_coding_gene CG15580 16-Dec-15 2015_12 viable FBgn0011448 l(3)neo4 lethal (3) neo4 http://flybase.net/reports/FBgn0011448.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016963 umpB uncoordinated with mechanoreceptor potential B http://flybase.net/reports/FBgn0016963.html gene 16-Dec-15 2015_12 FBgn0038805 TFAM mitochondrial transcription factor A http://flybase.net/reports/FBgn0038805.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0045893=positive regulation of transcription, DNA-templated, 0006979=response to oxidative stress, 0006264=mitochondrial DNA replication, 0006355=regulation of transcription, DNA-templated" "0005694=chromosome, 0005739=mitochondrion, 0005813=centrosome" "d-mttfa, mitochondrial transcription factor A, CG4217, Mitochondrial transcription factor A, mttfa, mitochondrial transcription factor, Mitochondiral transcription fctor a, tfam, d-tfam, mtTFA, MTTFA, D-mtTFA, d-TFAM, Tfam" IPR009071=High mobility group box domain CG4217 16-Dec-15 2015_12 WBGene00001975(hmg-5) ENSXETG00000005116(TFAM) ENSMUSG00000003923(Tfam) ENSG00000108064(TFAM) "oxidative stress response defective,short lived,male limited,visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC15552 K -0.204648371 0.386283051 -0.962932534 -0.056733272 1.86909438 1.09655433 FBgn0038161 CG9269 http://flybase.net/reports/FBgn0038161.html protein_coding_gene CG9269 16-Dec-15 2015_12 FBgn0053260 CG33260 http://flybase.net/reports/FBgn0053260.html FBgn0036445 protein_coding_gene "0003676=nucleic acid binding, 0000213=tRNA-intron endonuclease activity" 0000379=tRNA-type intron splice site recognition and cleavage 0000214=tRNA-intron endonuclease complex CG13470 "IPR006677=tRNA intron endonuclease, catalytic domain-like, IPR011856=tRNA endonuclease-like domain, IPR016690=tRNA-splicing endonuclease, SEN34 subunit" CG33260 16-Dec-15 2015_12 ENSDARG00000061370(si:ch211-203b8.3) WBGene00019535(K08D10.12) ENSXETG00000004597(TSEN34) viable FBgn0051949 CG31949 http://flybase.net/reports/FBgn0051949.html protein_coding_gene CG31949 16-Dec-15 2015_12 viable FBgn0262937 Rabex-5 Rabaptin-5-associated exchange factor for Rab5 ortholog (H. sapiens) http://flybase.net/reports/FBgn0262937.html "FBgn0262584, FBgn0035202" protein_coding_gene "0008270=zinc ion binding, 0017112=Rab guanyl-nucleotide exchange factor activity, 0003677=DNA binding, 0005085=guanyl-nucleotide exchange factor activity" "0007474=imaginal disc-derived wing vein specification, 0032483=regulation of Rab protein signal transduction, 0031398=positive regulation of protein ubiquitination, 0051036=regulation of endosome size, 0040015=negative regulation of multicellular organism growth, 0035214=eye-antennal disc development" "0030139=endocytic vesicle, 0045177=apical part of cell" "RabGEF1, Rabex5, Rabex-5, CG9139" "IPR002653=Zinc finger, A20-type, IPR003123=VPS9 domain" CG9139 16-Dec-15 2015_12 "ENSDARG00000014430(rabgef1),ENSDARG00000015968(rabgef1l)" WBGene00012644(rabx-5) ENSXETG00000026471(rabgef1) ENSMUSG00000025340(Rabgef1) ENSG00000154710(RABGEF1) FBgn0262843 CG43207 http://flybase.net/reports/FBgn0262843.html protein_coding_gene "DMG8-chr2R.33.031, lincRNA.382" CG43207 16-Dec-15 2015_12 FBgn0023082 fs(2)H47 fs(2)H47 http://flybase.net/reports/FBgn0023082.html gene unnamed 16-Dec-15 2015_12 "lethal,dominant,maternal effect" FBgn0017428 anon-67Ea anon-67Ea http://flybase.net/reports/FBgn0017428.html gene unnamed 16-Dec-15 2015_12 FBgn0000936 fs(2)A6 female sterile (2) A6 http://flybase.net/reports/FBgn0000936.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0038218 CG14841 http://flybase.net/reports/FBgn0038218.html FBgn0063759 protein_coding_gene BcDNA:AT04690 IPR007999=Protein of unknown function DUF745 CG14841 16-Dec-15 2015_12 viable DRSC27235 K -0.087467526 -0.184865914 0.411936883 0.903124814 -0.487829223 -1.762705236 FBgn0030982 CG7423 http://flybase.net/reports/FBgn0030982.html protein_coding_gene 0005515=protein binding 0030307=positive regulation of cell growth "0005634=nucleus, 0005829=cytosol" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG7423 16-Dec-15 2015_12 ENSDARG00000055562(mtpn) WBGene00016616(C43H6.3) ENSXETG00000010610(MTPN) ENSMUSG00000029840(Mtpn) ENSG00000105887(MTPN) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060576 l(3)S095414 lethal (3) S095414 http://flybase.net/reports/FBgn0060576.html gene 0954/14 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0002716 mei-W68 meiotic W68 http://flybase.net/reports/FBgn0002716.html "FBgn0022167, FBgn0050132, FBgn0065111" protein_coding_gene "0003677=DNA binding, 0003918=DNA topoisomerase type II (ATP-hydrolyzing) activity, 0005524=ATP binding" "0042139=early meiotic recombination nodule assembly, 0048477=oogenesis, 0007131=reciprocal meiotic recombination, 0000737=DNA catabolic process, endonucleolytic, 0042138=meiotic DNA double-strand break formation, 0000706=meiotic DNA double-strand break processing, 0042140=late meiotic recombination nodule assembly, 0006265=DNA topological change" 0005694=chromosome "mei W-68, Mei-W68, l(2)k05603, CG7753, meiW68, W68, MeiW68, spo11, mei, CG30132" "IPR002815=Spo11/DNA topoisomerase VI subunit A, IPR004085=DNA topoisomerase VI, subunit A, IPR013049=Spo11/DNA topoisomerase VI, subunit A, N-terminal" CG7753 16-Dec-15 2015_12 ENSDARG00000013837(spo11) YHL022C(SPO11) WBGene00004985(spo-11) ENSMUSG00000005883(Spo11) ENSG00000054796(SPO11) " adult stage | female , embryonic stage--P-stage , adult stage | male " " organism

, germarium region 3

, germarium region 2

, testis

" "viable,lethal,recessive,meiotic cell cycle defective,wild-type" "late recombination nodule,early recombination nodule" DRSC07649 K -0.912041242 -2.218252635 FBgn0035523 CG1311 http://flybase.net/reports/FBgn0035523.html protein_coding_gene IPR007603=Choline transporter-like CG1311 16-Dec-15 2015_12 "ENSDARG00000015946(LOC100333377),ENSDARG00000004568" ENSXETG00000000925(SLC44A1) "ENSMUSG00000028412(Slc44a1),ENSMUSG00000039865(Slc44a3)" "ENSG00000070214(SLC44A1),ENSG00000143036(SLC44A3)" viable FBgn0041164 armi armitage http://flybase.net/reports/FBgn0041164.html FBgn0035448 protein_coding_gene "0003678=DNA helicase activity, 0005515=protein binding" "0000578=embryonic axis specification, 0007616=long-term memory, 2000002=negative regulation of DNA damage checkpoint, 0016325=oocyte microtubule cytoskeleton organization, 0031023=microtubule organizing center organization, 0007319=negative regulation of oskar mRNA translation, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0048477=oogenesis, 0007293=germarium-derived egg chamber formation, 0046843=dorsal appendage formation, 0007318=pole plasm protein localization, 0016246=RNA interference, 0007317=regulation of pole plasm oskar mRNA localization" "0005739=mitochondrion, 0005737=cytoplasm, 0005829=cytosol, 0070725=Yb body, 0043186=P granule, 0043025=neuronal cell body, 0030424=axon, 0030425=dendrite, 0045202=synapse" "APC16, Armi, ARMI, CG11513, Armitage" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR026127=Probable RNA helicase SDE3" CG11513 16-Dec-15 2015_12 "ENSDARG00000061177(mov10b.1),ENSDARG00000056065(mov10b.2),ENSDARG00000015829(mov10a)" WBGene00016566(eri-7) ENSXETG00000022273(MOV10L1) ENSMUSG00000015365(Mov10l1) ENSG00000073146(MOV10L1) "female sterile,male sterile,partially,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,memory defective,recessive,fertile,viable" "egg,maternal effect,follicle cell,dorsal appendage,microtubule organizing center & oocyte,oocyte & microtubule organizing center,oocyte & microtubule" FBgn0036145 CG7607 http://flybase.net/reports/FBgn0036145.html FBgn0062424 protein_coding_gene "BcDNA:RH68451, CT23219" "IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG7607 16-Dec-15 2015_12 WBGene00043050(oig-4) "neuroanatomy defective,viable" "intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse" FBgn0264255 para paralytic http://flybase.net/reports/FBgn0264255.html "FBgn0260993, FBgn0003036, FBgn0001727, FBgn0003320, FBgn0002980, FBgn0000231" protein_coding_gene "0005509=calcium ion binding, 0005272=sodium channel activity, 0005248=voltage-gated sodium channel activity" "0007268=synaptic transmission, 0055085=transmembrane transport, 0046684=response to pyrethroid, 0006814=sodium ion transport, 0045433=male courtship behavior, veined wing generated song production, 0001666=response to hypoxia, 0046680=response to DDT, 0042493=response to drug, 0007638=mechanosensory behavior, 0009612=response to mechanical stimulus" "0005887=integral component of plasma membrane, 0005886=plasma membrane, 0001518=voltage-gated sodium channel complex" "DmNa[[V]], sbl-1, sbl, CG9907, DmNa[[v]], smell-blind, bas, paralyzed, bss, Out cold, lincRNA.S9469, bang sensitive, l(1)14Da, DmNav1, olfD, l(1)ESHS48, bangsenseless, par, DmNa[[v]]1, Ocd, Out-cold, smellblind, bang senseless, bang-senseless" "IPR005821=Ion transport domain, IPR001696=Voltage gated sodium channel, alpha subunit, IPR002048=EF-hand domain, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR010526=Sodium ion transport-associated, IPR028814=Sodium channel protein para, IPR024583=Voltage-gated Na+ ion channel, cytoplasmic domain" CG9907 16-Dec-15 2015_12 "ENSDARG00000034588(scn4ab),ENSDARG00000008797(scn4aa),ENSDARG00000018032(scn8ab),ENSDARG00000062744(scn1lab),ENSDARG00000005775(scn8aa),ENSDARG00000059692" ENSXETG00000014235(SCN4A) "ENSMUSG00000057182(Scn3a),ENSMUSG00000075318(Scn2a1),ENSMUSG00000064329(Scn1a),ENSMUSG00000075316(Scn9a),ENSMUSG00000023033(Scn8a),ENSMUSG00000001027(Scn4a),ENSMUSG00000032511(Scn5a),ENSMUSG00000034533(Scn10a)" "ENSG00000136531(SCN2A),ENSG00000153253(SCN3A),ENSG00000144285(SCN1A),ENSG00000169432(SCN9A),ENSG00000196876(SCN8A),ENSG00000007314(SCN4A),ENSG00000183873(SCN5A),ENSG00000185313(SCN10A),ENSG00000136546(SCN7A)" FBgn0061197 CG13164 http://flybase.net/reports/FBgn0061197.html FBgn0033709 protein_coding_gene "Syntaxin Interacting Protein 2, SIP2, Sip2, Syntaxin Interact. Prot. 2, CG13164" CG13164 16-Dec-15 2015_12 "viable,fertile" FBgn0010923 l(3)07615 lethal (3) 07615 http://flybase.net/reports/FBgn0010923.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060399 l(3)S132107b lethal (3) S132107b http://flybase.net/reports/FBgn0060399.html gene 1321/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0023129 aay astray http://flybase.net/reports/FBgn0023129.html FBgn0046476 protein_coding_gene "0005509=calcium ion binding, 0004647=phosphoserine phosphatase activity, 0000287=magnesium ion binding" "0007411=axon guidance, 0007422=peripheral nervous system development, 0048149=behavioral response to ethanol, 0045433=male courtship behavior, veined wing generated song production, 0006563=L-serine metabolic process, 0006564=L-serine biosynthetic process" 0005737=cytoplasm "0423/14, CG3705, anon-WO0172774.117, astray, 3-phosphoserine phosphatase, 24661601, Astray" "IPR023190=Phosphoserine phosphatase, domain 2, IPR023214=HAD-like domain, IPR004469=Phosphoserine phosphatase SerB, IPR006383=HAD-superfamily hydrolase, subfamily IB, PSPase-like" CG3705 16-Dec-15 2015_12 ENSDARG00000040314(zgc:112414) YGR208W(SER2) WBGene00013379(Y62E10A.13) ENSXETG00000010074(PSPH) ENSMUSG00000029446(Psph) ENSG00000146733(PSPH) "song defective,lethal,recessive,hyperactive,conditional,chemical resistant,lethal - all die before end of P-stage,some die during pharate adult stage,viable" intersegmental nerve FBgn0052174 CG32174 http://flybase.net/reports/FBgn0052174.html "FBgn0036720, FBgn0063610" protein_coding_gene 0006744=ubiquinone biosynthetic process 0005743=mitochondrial inner membrane CG3877 "IPR007715=Ubiquinone biosynthesis protein Coq4, IPR027540=Ubiquinone biosynthesis protein Coq4, eukaryotes" CG32174 16-Dec-15 2015_12 ENSDARG00000059759(si:dkey-170o10.3) YDR204W(COQ4) WBGene00000764(coq-4) ENSXETG00000003972(coq4) ENSMUSG00000026798(Coq4) ENSG00000167113(COQ4) FBgn0031815 frj farjavit http://flybase.net/reports/FBgn0031815.html protein_coding_gene 0071617=lysophospholipid acyltransferase activity 0030258=lipid modification 0016020=membrane "Frj, CG9526, Farjavit, MBOAT, CT26954" "IPR004299=Membrane bound O-acyl transferase, MBOAT" CG9526 16-Dec-15 2015_12 ENSDARG00000033436(mboat7) WBGene00008806(mboa-7) ENSXETG00000003174(MBOAT7) ENSMUSG00000035596(Mboat7) ENSG00000125505(MBOAT7) FBgn0058463 CG40463 http://flybase.net/reports/FBgn0058463.html protein_coding_gene 16-Dec-15 2015_12 FBgn0024843 p68 p68 http://flybase.net/reports/FBgn0024843.html gene 16-Dec-15 2015_12 FBgn0261799 dsx-c73A doublesex cognate 73A http://flybase.net/reports/FBgn0261799.html "FBgn0010368, FBgn0052159, FBgn0036632, FBgn0036633, FBgn0011429" protein_coding_gene 0005214=structural constituent of chitin-based cuticle 0040003=chitin-based cuticle development "0098595=perivitelline space, 0005576=extracellular region" "dsc73, CG4541, DSC73, lethal (3) j10E8, Drosophila secreted cuticle protein 73, CG32159, l(3)j10E8, CG13034, dsx-c73" CG32159 16-Dec-15 2015_12 FBgn0000196 bald bald http://flybase.net/reports/FBgn0000196.html gene bld 16-Dec-15 2015_12 "lethal,recessive,visible,cell autonomous" "cuticle,microchaeta" FBgn0039454 CG14247 http://flybase.net/reports/FBgn0039454.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14247 16-Dec-15 2015_12 viable FBgn0012009 tRNA:V4:70BCa transfer RNA:val4:70BCa http://flybase.net/reports/FBgn0012009.html "FBgn0003858, FBgn0012007, FBgn0052122, FBgn0060032" tRNA_gene "0033449=GUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:V4, tRNA:val4:70BCa, chr3L.trna37-ValAAC, valine tRNA, tRNA:V:AAC:AE002602-a, CR32122, tRNA[Val-AAC], AE002602.trna3-ValAAC, val-tRNA-4, tRNA-Val-4, tRNA[Val][[4]]" CR32122 16-Dec-15 2015_12 FBgn0031562 CG3604 http://flybase.net/reports/FBgn0031562.html FBgn0063121 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity BcDNA:LP04037 "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG3604 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,lethal,visible" "trichogen cell,mesothoracic tergum" DRSC00618 K 0.438313607 -0.71682055 -0.075709948 0.308573899 1.65510611 0.507486407 FBgn0265981 CR44760 http://flybase.net/reports/FBgn0265981.html non_protein_coding_gene lincRNA.375 CR44760 16-Dec-15 2015_12 FBgn0032812 Hakai Hakai http://flybase.net/reports/FBgn0032812.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0003676=nucleic acid binding, 0045296=cadherin binding, 0008270=zinc ion binding" "0035282=segmentation, 0016567=protein ubiquitination, 0007427=epithelial cell migration, open tracheal system, 0007015=actin filament organization, 0040003=chitin-based cuticle development, 0007391=dorsal closure, 0008258=head involution, 0007494=midgut development, 0060429=epithelium development" "0048471=perinuclear region of cytoplasm, 0016023=cytoplasmic membrane-bounded vesicle, 0005886=plasma membrane" "hakai, CG10263" "IPR001841=Zinc finger, RING-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR017907=Zinc finger, RING-type, conserved site" CG10263 16-Dec-15 2015_12 "ENSDARG00000015222(cbll1),ENSDARG00000045823(LOC100002706)" "short lived,semi-sterile,partially lethal - majority live,lethal,recessive,germline clone,embryonic/larval segmentation phenotype" "wing,leg,mechanosensory chaeta,somatic clone,supernumerary,embryonic/first instar larval cuticle,germline clone,denticle belt,denticle,epithelium,embryonic/larval midgut primordium,terminal tracheal cell" FBgn0069926 CG41125 http://flybase.net/reports/FBgn0069926.html FBan0041125 protein_coding_gene 16-Dec-15 2015_12 FBgn0065383 l(2)SH1656 lethal (2) SH1656 http://flybase.net/reports/FBgn0065383.html gene l(2)SH2 1656 16-Dec-15 2015_12 "lethal,recessive" FBgn0000509 anon-100Ca anon-100Ca http://flybase.net/reports/FBgn0000509.html gene "unnamed, doublesex cognate 100C, dsx-c100C" 16-Dec-15 2015_12 FBgn0043987 Su(rst)E218 Su(rst)E218 http://flybase.net/reports/FBgn0043987.html gene 0001745=compound eye morphogenesis E218 16-Dec-15 2015_12 viable eye FBgn0265045 Strn-Mlck Stretchin-Mlck http://flybase.net/reports/FBgn0265045.html "FBgn0013988, FBgn0015845, FBgn0034055, FBgn0043813, FBgn0062898, FBgn0034056" protein_coding_gene "0004687=myosin light chain kinase activity, 0005200=structural constituent of cytoskeleton, 0004674=protein serine/threonine kinase activity, 0004683=calmodulin-dependent protein kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation 0005875=microtubule associated complex "unnamed, Strn-MLCK, MLCK-3, CG15699, CG8304, MLC-kinase, Myosin light chain kinase, Strn/Mlck, A(225), A-band-protein-225, stretchin-MLCK, Strn-mlck, BEST:GH22543, MLCK-2, 143736_at, Stretchin, CT41348, strn-mlck, Mlc-k, mlck, BcDNA:RH74685, Stretchin-MLCK, myosin light chain kinase, 225kD protein, CG18255, MLCK, MLCK-1, CG44162, Mlck" "IPR017441=Protein kinase, ATP binding site, IPR003961=Fibronectin type III, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR020675=Myosin light chain kinase-related, IPR007110=Immunoglobulin-like domain" CG44162 16-Dec-15 2015_12 ENSDARG00000016936 "ENSXETG00000017411(HMCN1),ENSXETG00000001353()" "ENSMUSG00000066842(Hmcn1),ENSMUSG00000055632(Hmcn2)" " embryonic stage | stage >14 , adult stage , pupal stage | late , embryonic stage , embryonic stage -- adult stage " " larval muscle system

,

ubiquitous " FBgn0036447 CG17173 http://flybase.net/reports/FBgn0036447.html protein_coding_gene "0008454=alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity" 0005975=carbohydrate metabolic process 0016020=membrane dMGAT4-2 IPR006759=Glycosyl transferase family 54 CG17173 16-Dec-15 2015_12 viable FBgn0003433 slt slight http://flybase.net/reports/FBgn0003433.html gene 16-Dec-15 2015_12 "visible,viable,fertile" macrochaeta FBgn0265698 CR44505 http://flybase.net/reports/FBgn0265698.html non_protein_coding_gene lincRNA.349 CR44505 16-Dec-15 2015_12 FBgn0022025 l(2)k08915 lethal (2) k08915 http://flybase.net/reports/FBgn0022025.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065320 l(2)SH1918 lethal (2) SH1918 http://flybase.net/reports/FBgn0065320.html gene l(2)SH2 1918 16-Dec-15 2015_12 "lethal,recessive" FBgn0002366 l(3)89Aa lethal (3) 89Aa http://flybase.net/reports/FBgn0002366.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060920 l(3)S042415 lethal (3) S042415 http://flybase.net/reports/FBgn0060920.html gene 0424/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0036691 beg bad egg http://flybase.net/reports/FBgn0036691.html protein_coding_gene "0016740=transferase activity, 0004314=[acyl-carrier-protein] S-malonyltransferase activity" 0006633=fatty acid biosynthetic process 0005739=mitochondrion "bad egg, beg, CG7842" "IPR014043=Acyl transferase, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase, IPR016036=Malonyl-CoA ACP transacylase, ACP-binding, IPR001227=Acyl transferase domain" CG7842 16-Dec-15 2015_12 ENSDARG00000016613(mcat) WBGene00016812(C50D2.9) ENSXETG00000003269(BC074523.1) ENSMUSG00000048755(Mcat) ENSG00000100294(MCAT) viable FBgn0261527 vainsB vainsB http://flybase.net/reports/FBgn0261527.html protein_coding_gene 16-Dec-15 2015_12 smell perception defective FBgn0262390 mir-303 mir-303 stem loop http://flybase.net/reports/FBgn0262390.html "FBgn0067702, FBgn0262217" miRNA_gene "Mir-303, mir-303, mIR-303, CR33606, CR42924, miR-303, dme-mir-303" CR42924 16-Dec-15 2015_12 "visible,viable,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing vein,ectopic,wing,wing margin" FBgn0065345 l(2)SH1819 lethal (2) SH1819 http://flybase.net/reports/FBgn0065345.html gene l(2)SH2 1819 16-Dec-15 2015_12 "lethal,recessive" FBgn0266448 CG45078 http://flybase.net/reports/FBgn0266448.html "FBgn0020439, FBgn0063173" protein_coding_gene CG6544 CG45078 16-Dec-15 2015_12 FBgn0029928 CG3032 http://flybase.net/reports/FBgn0029928.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG3032 16-Dec-15 2015_12 FBgn0022391 Lap-6 Leucine aminopeptidase 6 http://flybase.net/reports/FBgn0022391.html gene "LAP6, leucyl aminopeptidase, LAP-6" 16-Dec-15 2015_12 FBgn0046662 anon-38C.39 anon-38C.39 http://flybase.net/reports/FBgn0046662.html gene 38C.39 16-Dec-15 2015_12 FBgn0030367 Cyp311a1 Cyp311a1 http://flybase.net/reports/FBgn0030367.html protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG1488, 311a1, cytochrome P450" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG1488 16-Dec-15 2015_12 YMR015C(ERG5) lethal FBgn0001771 l(1)M42 lethal (1) M42 http://flybase.net/reports/FBgn0001771.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0013394 anon-64Bb anon-64Bb http://flybase.net/reports/FBgn0013394.html gene 16-Dec-15 2015_12 FBgn0014103 anon-4Cb anon-4Cb http://flybase.net/reports/FBgn0014103.html gene "T3, Transcript 3" 16-Dec-15 2015_12 FBgn0028627 l(2)00434a lethal (2) 00434a http://flybase.net/reports/FBgn0028627.html gene l(2)00434 16-Dec-15 2015_12 "lethal,recessive" FBgn0264544 CG43923 http://flybase.net/reports/FBgn0264544.html protein_coding_gene CG43923 16-Dec-15 2015_12 FBgn0052460 tRNA:CR32460 transfer RNA:CR32460 http://flybase.net/reports/FBgn0052460.html FBgn0060244 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002647.trna2-GluCTC, chr3L.trna33-GluCTC, tRNA:E:CTC:AE002647, CR32460" CR32460 16-Dec-15 2015_12 FBgn0267803 CR46128 http://flybase.net/reports/FBgn0267803.html non_protein_coding_gene CR46128 16-Dec-15 2015_12 FBgn0085484 Pdxk Pyridoxal kinase http://flybase.net/reports/FBgn0085484.html "FBgn0035979, FBan0004446" protein_coding_gene 0008478=pyridoxal kinase activity "0009443=pyridoxal 5'-phosphate salvage, 0071326=cellular response to monosaccharide stimulus" 0005737=cytoplasm "CG34455, dPdxk, CG4446" "IPR029056=Ribokinase-like, IPR004625=Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase, IPR013749=Pyridoxamine kinase/Phosphomethylpyrimidine kinase" CG34455 16-Dec-15 2015_12 "ENSDARG00000032640(pdxka),ENSDARG00000036546(LOC564697)" YEL029C(BUD16) WBGene00019008(F57C9.1) ENSXETG00000017875(PDXK) "ENSMUSG00000032788(Pdxk),ENSMUSG00000002791(Pdxk-ps)" ENSG00000160209(PDXK) "lethal,DNA repair defective,recessive" FBgn0031190 CG12576 http://flybase.net/reports/FBgn0031190.html FBgn0044590 protein_coding_gene anon-WO0140519.40 CG12576 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of larval stage" DRSC20621 K 0.72803654 -0.388277836 0.066494579 -0.915016098 1.661460617 -0.640906316 FBgn0001739 l(1)HM9 lethal (1) HM9 http://flybase.net/reports/FBgn0001739.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0266696 CG45186 http://flybase.net/reports/FBgn0266696.html "FBgn0261551, FBgn0052306, FBgn0035339, FBgn0035340, FBgn0035341, FBgn0035342, FBgn0040693, FBgn0053231, FBgn0035347, FBgn0035345, FBgn0053232, FBgn0035338" protein_coding_gene 0003779=actin binding 0007010=cytoskeleton organization "CG13797, CG13798, CG13799, CG16763, Villin-like, CG33232, CG42669, unnamed, CG12790, c62E-11, CG33231, CG16764, villin-like, CG1141, CG13800, CG32306" "IPR003128=Villin headpiece, IPR007122=Villin/Gelsolin, IPR029006=ADF-H/Gelsolin-like domain" CG45186 16-Dec-15 2015_12 ENSDARG00000055075(svil) WBGene00015691(viln-1) ENSXETG00000002662(SVIL) ENSMUSG00000024236(Svil) FBgn0000841 fs(1)M28 female sterile (1) M28 http://flybase.net/reports/FBgn0000841.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0022398 Gase4 Gastric serine protease 4 http://flybase.net/reports/FBgn0022398.html gene 0008236=serine-type peptidase activity 16-Dec-15 2015_12 FBgn0027641 l(3)SCEI-2 lethal (3) SCEI-2 http://flybase.net/reports/FBgn0027641.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0067667 p55M p55M http://flybase.net/reports/FBgn0067667.html gene p55 16-Dec-15 2015_12 FBgn0034825 CG3215 http://flybase.net/reports/FBgn0034825.html protein_coding_gene "0042803=protein homodimerization activity, 0004367=glycerol-3-phosphate dehydrogenase [NAD+] activity, 0051287=NAD binding" "0055114=oxidation-reduction process, 0046168=glycerol-3-phosphate catabolic process, 0006072=glycerol-3-phosphate metabolic process, 0005975=carbohydrate metabolic process" 0009331=glycerol-3-phosphate dehydrogenase complex gpdh-2 "IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011128=Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal, IPR006168=Glycerol-3-phosphate dehydrogenase, NAD-dependent, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR006109=Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal, IPR016040=NAD(P)-binding domain, IPR017751=Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic" CG3215 16-Dec-15 2015_12 "YDL022W(GPD1),YOL059W(GPD2)" viable FBgn0262406 let-7 let-7 http://flybase.net/reports/FBgn0262406.html "FBgn0260473, FBgn0043885, FBgn0262242" miRNA_gene "0010629=negative regulation of gene expression, 0071390=cellular response to ecdysone, 0016319=mushroom body development, 0040034=regulation of development, heterochronic, 0007552=metamorphosis" "CR42949, let-7-C, dme-let-7, let7, CR32968, Let-7" CR42949 16-Dec-15 2015_12 FBgn0001913 l(2)25Ab lethal (2) 25Ab http://flybase.net/reports/FBgn0001913.html gene "l(2)jf9, jf9" 16-Dec-15 2015_12 lethal FBgn0052214 CG32214 http://flybase.net/reports/FBgn0052214.html protein_coding_gene CG32214 16-Dec-15 2015_12 FBgn0024651 l(2)k08707 lethal (2) k08707 http://flybase.net/reports/FBgn0024651.html gene 87/7 16-Dec-15 2015_12 "lethal,recessive" FBgn0267018 CR45462 http://flybase.net/reports/FBgn0267018.html non_protein_coding_gene CR45462 16-Dec-15 2015_12 FBgn0051909 CG31909 http://flybase.net/reports/FBgn0051909.html FBgn0045239 protein_coding_gene NEST:bs19e08 CG31909 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0023060 l(1)2Dm lethal (1) 2Dm http://flybase.net/reports/FBgn0023060.html gene "B2/35.2, C3/50.71" 16-Dec-15 2015_12 "lethal,recessive" FBgn0020260 peo pendolino http://flybase.net/reports/FBgn0020260.html gene 0007067=mitotic nuclear division pen 16-Dec-15 2015_12 FBgn0267954 CR46234 http://flybase.net/reports/FBgn0267954.html non_protein_coding_gene lincRNA.346 CR46234 16-Dec-15 2015_12 FBgn0264991 CG44142 http://flybase.net/reports/FBgn0264991.html protein_coding_gene CG44142 16-Dec-15 2015_12 FBgn0259726 CG42380 http://flybase.net/reports/FBgn0259726.html protein_coding_gene "CG9865(uORF3), Dromel_CG9865_FBtr0071680_cx9c_uorf3" CG42380 16-Dec-15 2015_12 FBgn0024980 Syx4 Syntaxin 4 http://flybase.net/reports/FBgn0024980.html protein_coding_gene "0005484=SNAP receptor activity, 0000149=SNARE binding" "0007269=neurotransmitter secretion, 0061025=membrane fusion, 0016192=vesicle-mediated transport, 0016081=synaptic vesicle docking, 0002121=inter-male aggressive behavior" "0005886=plasma membrane, 0005737=cytoplasm, 0031201=SNARE complex" "syntaxin, EG:95B7.1, Syx-4, Syx, syx4, EG:95B7.11, Syntaxin, Dm Syx4, CG2715, DmSyx4, syntaxin 4" "IPR010989=t-SNARE, IPR000727=Target SNARE coiled-coil homology domain, IPR006011=Syntaxin, N-terminal domain" CG2715 16-Dec-15 2015_12 "behavior defective,recessive,viable" FBgn0058073 CG40073 http://flybase.net/reports/FBgn0058073.html protein_coding_gene 16-Dec-15 2015_12 FBgn0015446 l(1)7Fg lethal (1) 7Fg http://flybase.net/reports/FBgn0015446.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264955 CR44124 http://flybase.net/reports/FBgn0264955.html non_protein_coding_gene CR44124 16-Dec-15 2015_12 FBgn0267970 CR46248 http://flybase.net/reports/FBgn0267970.html non_protein_coding_gene CR46248 16-Dec-15 2015_12 FBgn0063596 CS3-4 "Calcineurin suppressor, chromosome 3, group 4" http://flybase.net/reports/FBgn0063596.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002443 l(3)PR lethal Payne Right http://flybase.net/reports/FBgn0002443.html gene l (3) Payne Right 16-Dec-15 2015_12 "lethal,recessive" FBgn0034310 Nup75 Nucleoporin 75kD http://flybase.net/reports/FBgn0034310.html protein_coding_gene 0017056=structural constituent of nuclear pore "2000331=regulation of terminal button organization, 0006607=NLS-bearing protein import into nucleus, 0007184=SMAD protein import into nucleus, 0006406=mRNA export from nucleus" 0031080=nuclear pore outer ring "Nup 75, CG5733, Nucleoporin 75, nup75" IPR011502=Nucleoporin Nup85-like CG5733 16-Dec-15 2015_12 ENSDARG00000046061(pcnt1) WBGene00003788(npp-2) ENSXETG00000027060(Q6DK84_XENTR) ENSMUSG00000020739(Nup85) ENSG00000125450(NUP85) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004841 TkR86C Tachykinin-like receptor at 86C http://flybase.net/reports/FBgn0004841.html FBgn0015775 protein_coding_gene "0008188=neuropeptide receptor activity, 0004950=chemokine receptor activity, 0004995=tachykinin receptor activity" "0006935=chemotaxis, 0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0002121=inter-male aggressive behavior, 0007217=tachykinin receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "NKr, neurokinin receptor from Drosophila, TAKR86C, NKD, Nkd, TakR86C, Neuropeptide receptor, Takr86C, CG6515, Tachykinin receptor, DmNTLR, NKD12, natalisin receptor" "IPR000355=Chemokine receptor family, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR001681=Neurokinin receptor" CG6515 16-Dec-15 2015_12 WBGene00016761(C49A9.7) viable FBgn0003721 Tm1 Tropomyosin 1 http://flybase.net/reports/FBgn0003721.html "FBgn0010776, FBgn0011036, FBgn0015832, FBgn0015833, FBgn0046771, FBgn0046800, FBgn0060408, FBgn0064771" protein_coding_gene "0051015=actin filament binding, 0003779=actin binding" "0007315=pole plasm assembly, 0048477=oogenesis, 0006936=muscle contraction, 0045451=pole plasm oskar mRNA localization, 0048813=dendrite morphogenesis, 0010591=regulation of lamellipodium assembly" "0016529=sarcoplasmic reticulum, 0031941=filamentous actin, 0005862=muscle thin filament tropomyosin, 0030017=sarcomere, 0070865=investment cone, 0005829=cytosol" "l(3)S130510, l(3)s2958, unnamed, cytoplasmic tropomyosin, chr3R:11122272..11122408, cTmII, TmII, 2299, troponin H, cTM, Tropomyosin II, TnH, BcDNA:SD21996, tropomyosinII, DmTm1, cytoskeletal Tropomyosin, Troponin H, l(3)02299, PmI, tm1, 1305/10, CG4898, TM1, mTmII, Tropomyosin-1, Tm, TM, tmII, Dm Tm1, TMII, TnH-33, BcDNA:GH09289, TmH, tropomysin II, TmH34, TmH-34, Tropomyosin, tropomyosin II, Dm TmH33, tropomyosin, troponin-H isoform 34, TmH-33, Dm TmH34, TnH-34, cTm, region 3, Tropomyosin I, Tmr34, Tmr33, troponin-H, TmH33, BcDNA:LD37158" IPR000533=Tropomyosin CG4898 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage S10-12 , embryonic stage | >3-6 hr , embryonic stage | stage 11 , embryonic stage | early , embryonic stage | stage >=13 , embryonic stage | stage 6-15 , embryonic stage | stage 13 , embryonic stage | stage 6-11 , embryonic stage | 0-6 hr " " nurse cell

, ectoderm | segmentally repeated

, follicle cell

, embryo | posterior

, embryonic cortex

, embryonic central nervous system

, anterior midgut proper primordium

, dorsal ectoderm

, ventral furrow

, cephalic furrow

, embryonic brain

, midgut constriction

, germ band

, posterior midgut proper primordium

" "sterile,germline clone,maternal effect,neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,behavior defective,lethal - all die before end of larval stage,some die during larval stage,grandchildless,visible,partially lethal - majority die,some die during pupal stage" "dorsal multidendritic neuron ddaE & dendrite,dendritic arborising neuron & dendrite,border follicle cell,somatic clone,nucleus | embryonic stage 4,chromosome | embryonic stage,dorsal multidendritic neuron ddaC & dendrite | somatic clone,germline cell,maternal effect,embryonic/larval pharynx,pole cell,mesothoracic tergum" DRSC13082 IE 1.670302711 0.021977576 1.814198538 -0.873519074 -0.745466217 -0.199712242 FBgn0085741 CR40528 http://flybase.net/reports/FBgn0085741.html FBan0040528 rRNA_gene CR40528 16-Dec-15 2015_12 FBgn0002817 ms(2)2 male sterile (2) 2 http://flybase.net/reports/FBgn0002817.html gene "male-sterile, ms" 16-Dec-15 2015_12 "sterile,male,fertile,female,partially" FBgn0002201 l(3)67Ae lethal (3) 67Ae http://flybase.net/reports/FBgn0002201.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,recessive" FBgn0015373 clg clootie dumpling http://flybase.net/reports/FBgn0015373.html gene 16-Dec-15 2015_12 FBgn0259281 EP-500.2 http://flybase.net/reports/FBgn0259281.html gene 16-Dec-15 2015_12 visible wing FBgn0031504 CG15403 http://flybase.net/reports/FBgn0031504.html protein_coding_gene IPR009688=Domain of unknown function DUF1279 CG15403 16-Dec-15 2015_12 ENSDARG00000052638 ENSMUSG00000027495(2010011I20Rik) ENSG00000124098(C20orf108) viable FBgn0036085 CG6527 http://flybase.net/reports/FBgn0036085.html FBgn0063737 protein_coding_gene 0005789=endoplasmic reticulum membrane BcDNA:AT13283 "IPR008962=PapD-like, IPR016763=Vesicle-associated membrane-protein-associated protein, IPR000535=Major sperm protein (MSP) domain" CG6527 16-Dec-15 2015_12 viable FBgn0053647 CG33647 http://flybase.net/reports/FBgn0053647.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33647 16-Dec-15 2015_12 FBgn0039313 CG11892 http://flybase.net/reports/FBgn0039313.html protein_coding_gene "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG11892 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" "viable,fertile" FBgn0060932 l(3)S041608 lethal (3) S041608 http://flybase.net/reports/FBgn0060932.html gene 0416/08 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0083256 E(smoDN)A Enhancer of smoDN group A http://flybase.net/reports/FBgn0083256.html gene 0007224=smoothened signaling pathway Group A 16-Dec-15 2015_12 "lethal,recessive,cell lethalcell lethal,somatic clone" FBgn0013493 l(1)9PP1 lethal (1) 9PP1 http://flybase.net/reports/FBgn0013493.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" "segment,germline clone" FBgn0266131 161Y http://flybase.net/reports/FBgn0266131.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0267071 CR45515 http://flybase.net/reports/FBgn0267071.html non_protein_coding_gene CR45515 16-Dec-15 2015_12 FBgn0264438 CR43856 http://flybase.net/reports/FBgn0264438.html non_protein_coding_gene lincRNA.140 CR43856 16-Dec-15 2015_12 FBgn0016916 misn missensed http://flybase.net/reports/FBgn0016916.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 "lethal,recessive" "neuron & peripheral nervous system,peripheral nervous system,neuron,presumptive embryonic/larval peripheral nervous system" FBgn0263548 mir-4957 mir-4957 stem loop http://flybase.net/reports/FBgn0263548.html miRNA_gene "dme-mir-4957, CR43533" CR43533 16-Dec-15 2015_12 FBgn0264258 Roc1a::Roc2 http://flybase.net/reports/FBgn0264258.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0022140 l(2)k06205 lethal (2) k06205 http://flybase.net/reports/FBgn0022140.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0266939 CR45390 http://flybase.net/reports/FBgn0266939.html non_protein_coding_gene CR45390 16-Dec-15 2015_12 FBgn0061075 l(3)S015110b lethal (3) S015110b http://flybase.net/reports/FBgn0061075.html gene "l(3)S015110, 0151/10" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038472 CG3995 http://flybase.net/reports/FBgn0038472.html protein_coding_gene 0003677=DNA binding "IPR003656=Zinc finger, BED-type, IPR028002=Myb/SANT-like DNA-binding domain" CG3995 16-Dec-15 2015_12 "viable,fertile" FBgn0031082 CG17003 http://flybase.net/reports/FBgn0031082.html protein_coding_gene 0019799=tubulin N-acetyltransferase activity 0071929=alpha-tubulin acetylation 0005874=microtubule IPR007965=Alpha-tubulin N-acetyltransferase CG17003 16-Dec-15 2015_12 WBGene00003178(mec-17) "viable,body color defective" mesothoracic tergum FBgn0031323 CG5139 http://flybase.net/reports/FBgn0031323.html protein_coding_gene CG5139 16-Dec-15 2015_12 viable FBgn0052192 CG32192 http://flybase.net/reports/FBgn0052192.html "FBgn0045082, FBgn0045108" protein_coding_gene "bs33g12.y1, NEST:bs36a12, NEST:bs33g12" CG32192 16-Dec-15 2015_12 viable FBgn0001444 l(1)7Cf lethal (1) 7Cf http://flybase.net/reports/FBgn0001444.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect,neurogenic phenotype,lethal - all die before end of larval stage,partially,rescuable maternal effect,some die during larval stage" FBgn0040064 yip2 yippee interacting protein 2 http://flybase.net/reports/FBgn0040064.html FBgn0032158 protein_coding_gene 0003988=acetyl-CoA C-acyltransferase activity 0006635=fatty acid beta-oxidation "0005875=microtubule associated complex, 0005739=mitochondrion, 0005811=lipid particle" "CG4600, ACAA, Yip2, Yippee interacting protein 2, acetyl-CoA acyltransferase" "IPR016039=Thiolase-like, IPR020610=Thiolase, active site, IPR020615=Thiolase, acyl-enzyme intermediate active site, IPR020616=Thiolase, N-terminal, IPR020613=Thiolase, conserved site, IPR020617=Thiolase, C-terminal, IPR002155=Thiolase" CG4600 16-Dec-15 2015_12 ENSDARG00000038881(acaa2) WBGene00009952(F53A2.7) ENSXETG00000020333(ACAA2) ENSMUSG00000036880(Acaa2) ENSG00000167315(ACAA2) viable FBgn0014940 anon-98Da anon-98Da http://flybase.net/reports/FBgn0014940.html gene unnamed 16-Dec-15 2015_12 FBgn0031253 CG11885 http://flybase.net/reports/FBgn0031253.html FBgn0061458 protein_coding_gene 0000502=proteasome complex BcDNA:AT13539 IPR018788=Proteasome assembly chaperone 3 CG11885 16-Dec-15 2015_12 FBgn0063923 Kaz1-ORFB Kaz1-ORFB http://flybase.net/reports/FBgn0063923.html "FBgn0026414, FBtr0072489, FBpp0072391, FBpp0072392, FBtr0072491, FBpp0072393, FBpp0072394, FBpp0072395, FBtr0072494, FBpp0072396" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0030162=regulation of proteolysis "KAZ1 type C1, ORF D, ORF B, Kaz1, KAZ1 type E, KAZ1 type D, KAZ1 type C3, ORF E, KAZ1 type C2, CG33045, ORF C, KAZ1 type beta, CG1220" IPR002350=Kazal domain CG1220 16-Dec-15 2015_12 FBgn0260407 mRpS23 mitochondrial ribosomal protein S23 http://flybase.net/reports/FBgn0260407.html "FBgn0065862, FBgn0051842" protein_coding_gene 0003735=structural constituent of ribosome "0032543=mitochondrial translation, 0006412=translation" 0005761=mitochondrial ribosome "CG31842, mRpS23, mitochondrial Ribosomal protein S23, l(2)SH0272, lethal (2) SH0272, l(2)SH2 0272" "IPR023611=Ribosomal protein S23/S25, mitochondrial, IPR019520=Ribosomal protein S23/Rsm25, mitochondrial" CG31842 16-Dec-15 2015_12 ENSDARG00000033973(mrps23) WBGene00014224(ZK1098.7) ENSXETG00000016140(MRPS23) ENSMUSG00000023723(Mrps23) ENSG00000181610(MRPS23) FBgn0005600 yemG4 yema gene 4 http://flybase.net/reports/FBgn0005600.html FBgn0004042 gene "yG4, unnamed, yT4" 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage | stage >=13 , larval stage--adult stage , larval stage--pupal stage , embryonic stage | stage <6 , embryonic stage | stage <=8 , adult stage && oogenesis stage | stage S7-10B , embryonic stage | 12-18 hr , adult stage && oogenesis stage | stage S9-10B " " ovary

, embryonic proventriculus

, hindgut

, imaginal disc

, organism

, nurse cell

, central nervous system

, proventriculus

, oocyte

, spermatocyte

" FBgn0039554 CG5003 http://flybase.net/reports/FBgn0039554.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXL8 IPR001810=F-box domain CG5003 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0030294 Pa1 PTIP associated 1 http://flybase.net/reports/FBgn0030294.html "FBgn0047031, FBgn0047174" protein_coding_gene 0051568=histone H3-K4 methylation 0044666=MLL3/4 complex "BcDNA:RE09126, dPA1, BcDNA:RH21749, PA1, CG11750" IPR028213=PTIP-associated protein 1 CG11750 16-Dec-15 2015_12 "viable,fertile" FBgn0040706 CG12677 http://flybase.net/reports/FBgn0040706.html FBgn0063351 protein_coding_gene "DIGF-8, BcDNA:AT09846" IPR029277=Single domain Von Willebrand factor type C domain 16-Dec-15 2015_12 FBgn0265832 CR44621 http://flybase.net/reports/FBgn0265832.html non_protein_coding_gene lincRNA.986 CR44621 16-Dec-15 2015_12 FBgn0024523 l(3)j2D5 lethal (3) j2D5 http://flybase.net/reports/FBgn0024523.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259423 C547 http://flybase.net/reports/FBgn0259423.html gene 16-Dec-15 2015_12 visible "wing,chaeta" FBgn0060940 l(3)S039807 lethal (3) S039807 http://flybase.net/reports/FBgn0060940.html gene 0398/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065454 l(2)SH1393 lethal (2) SH1393 http://flybase.net/reports/FBgn0065454.html gene l(2)SH2 1393 16-Dec-15 2015_12 "lethal,recessive" FBgn0015952 jockey\pol pol http://flybase.net/reports/FBgn0015952.html transposable_element_gene "joc, jockey pol, ORF2, Jockey RTase, RT" "IPR005135=Endonuclease/exonuclease/phosphatase, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0031830 COX5B Cytochrome c oxidase subunit 5B http://flybase.net/reports/FBgn0031830.html "FBgn0025316, FBgn0062184, FBgn0064803" protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" "0005811=lipid particle, 0005739=mitochondrion, 0005751=mitochondrial respiratory chain complex IV" "Cytochrome c oxidase Polypeptide VB, CcO Vb, Cytochrome c oxidase Vb, Cytochrome c oxidase polypeptide Vb, CG11015, COXB, Cytochrome c oxidase Polypeptide Vb, BcDNA:RH49324, Subunit Vb, anon-EST:Posey143, Cytochrome c oxidase subunit Vb, anon-WO0118547.187, CoVb, Vb" "IPR002124=Cytochrome c oxidase, subunit Vb" CG11015 16-Dec-15 2015_12 "ENSDARG00000015978(zgc:86599),ENSDARG00000068738(zgc:153978),ENSDARG00000011208(LOC100002384)" WBGene00000371(cco-1) "ENSXETG00000001255(TGas113h12.1),ENSXETG00000025435(TEgg041e07.1)" "ENSMUSG00000079941,ENSMUSG00000061518(Cox5b)" ENSG00000135940(COX5B) "stress response defective,aging defective,lethal,RU486 conditional,developmental rate defective,female sterile,short lived,male,female,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0041627 Ku80 Ku80 http://flybase.net/reports/FBgn0041627.html "FBgn0028843, FBgn0042128" protein_coding_gene "0042162=telomeric DNA binding, 0017116=single-stranded DNA-dependent ATP-dependent DNA helicase activity, 0003684=damaged DNA binding, 0004003=ATP-dependent DNA helicase activity" "0071480=cellular response to gamma radiation, 0006303=double-strand break repair via nonhomologous end joining, 0006310=DNA recombination, 0000723=telomere maintenance, 0045471=response to ethanol" "0017117=single-stranded DNA-dependent ATP-dependent DNA helicase complex, 0043564=Ku70:Ku80 complex" "BG:DS09217.6, ku80, CG18801, Ku, KU80, DmKu80" "IPR002035=von Willebrand factor, type A, IPR005161=Ku70/Ku80, N-terminal alpha/beta, IPR024193=Ku80, IPR006164=Ku70/Ku80 beta-barrel domain, IPR016194=SPOC-like, C-terminal domain, IPR005160=Ku70/Ku80 C-terminal arm, IPR014893=Ku, C-terminal" CG18801 16-Dec-15 2015_12 "ENSDARG00000068862(xrcc5),ENSDARG00000015599(LOC100331090)" ENSMUSG00000026187(Xrcc5) ENSG00000079246(XRCC5) viable FBgn0259419 EP-643 http://flybase.net/reports/FBgn0259419.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta" FBgn0031284 CG3876 http://flybase.net/reports/FBgn0031284.html protein_coding_gene 0008565=protein transporter activity 0006506=GPI anchor biosynthetic process "0000139=Golgi membrane, 0005789=endoplasmic reticulum membrane" IPR019402=Frag1/DRAM/Sfk1 CG3876 16-Dec-15 2015_12 ENSDARG00000044596(pgap2) WBGene00007045(tag-189) ENSMUSG00000030990(Pgap2) ENSG00000148985(PGAP2) viable DRSC00632 K -0.205007968 -0.124357886 0.291561884 -0.028714144 -0.382654175 2.909254207 FBgn0045846 mdg1\ORF2 ORF2 http://flybase.net/reports/FBgn0045846.html transposable_element_gene 16-Dec-15 2015_12 FBgn0025165 l(2)38EFf lethal (2) 38EFf http://flybase.net/reports/FBgn0025165.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031926 CG6739 http://flybase.net/reports/FBgn0031926.html protein_coding_gene "IPR020067=Frizzled domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG6739 16-Dec-15 2015_12 FBgn0027253 l(1)G0250 lethal (1) G0250 http://flybase.net/reports/FBgn0027253.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0082188 l(3)S033513 lethal (3) S033513 http://flybase.net/reports/FBgn0082188.html gene 16-Dec-15 2015_12 "lethal,viable,fertile,female,recessive,female sterile,sterile" "ovary,ovariole,egg chamber" FBgn0069967 CG41040 http://flybase.net/reports/FBgn0069967.html FBan0041040 protein_coding_gene 16-Dec-15 2015_12 FBgn0030688 CG8952 http://flybase.net/reports/FBgn0030688.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP52 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG8952 16-Dec-15 2015_12 viable FBgn0013692 mt:tRNA:E mitochondrial glutamic acid tRNA http://flybase.net/reports/FBgn0013692.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "tRNA[Glu], CR34081, tRNA Glu, mtdbD00006306" CR34081 16-Dec-15 2015_12 FBgn0060813 l(3)S054203b lethal (3) S054203b http://flybase.net/reports/FBgn0060813.html gene 0542/03 16-Dec-15 2015_12 lethal FBgn0058380 CG40380 http://flybase.net/reports/FBgn0058380.html protein_coding_gene 16-Dec-15 2015_12 DRSC20764 I 1.645489539 -0.73748131 -0.088650678 -0.265914048 FBgn0011861 tRNA:G3:28D transfer RNA:gly3:28D http://flybase.net/reports/FBgn0011861.html "FBgn0051903, FBgn0060224" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002690.trna2-GlyGCC, tRNA:G:GCC:AE002690-a, chr2L.trna10-GlyGCC, tRNA[Gly-GCC], tRNA:gly3:28D, CR31903" CR31903 16-Dec-15 2015_12 FBgn0005187 l(2)S42 lethal of Seto 42 http://flybase.net/reports/FBgn0005187.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "eye,adult head" FBgn0044350 ftz-f1::Hr39 ftz-f1::Hr39 http://flybase.net/reports/FBgn0044350.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0262722 CR43166 http://flybase.net/reports/FBgn0262722.html non_protein_coding_gene "CG43166, lincRNA.842, mdcds_43034" CR43166 16-Dec-15 2015_12 FBgn0039683 dmrt99B doublesex-Mab related 99B http://flybase.net/reports/FBgn0039683.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG15504, unnamed" "IPR005173=DMRTA motif, IPR001275=DM DNA-binding domain, IPR009060=UBA-like, IPR026607=DMRT/protein doublesex/protein male abnormal 3" CG15504 16-Dec-15 2015_12 ENSDARG00000035290(dmrt3a) WBGene00017326(dmd-5) "ENSXETG00000005462(DMRTA1),ENSXETG00000002846(DMRTA2)" "ENSMUSG00000047143(Dmrta2),ENSMUSG00000043753(Dmrta1)" FBgn0002170 l(2)Sp12 lethal (2) Sp12 http://flybase.net/reports/FBgn0002170.html gene 16-Dec-15 2015_12 lethal FBgn0038109 CG11656 http://flybase.net/reports/FBgn0038109.html FBgn0044676 protein_coding_gene anon-WO0140519.199 CG11656 16-Dec-15 2015_12 viable FBgn0023534 CG17778 http://flybase.net/reports/FBgn0023534.html FBgn0062971 protein_coding_gene "EG:171D11.5, BcDNA:RH02374" CG17778 16-Dec-15 2015_12 viable FBgn0266270 Hto-WP(3)TRG http://flybase.net/reports/FBgn0266270.html gene 16-Dec-15 2015_12 eye FBgn0001896 l(2)21Fb lethal (2) 21Fb http://flybase.net/reports/FBgn0001896.html gene "l(2)neh10, l(2)neh-10" 16-Dec-15 2015_12 lethal FBgn0058166 CG40166 http://flybase.net/reports/FBgn0058166.html protein_coding_gene 16-Dec-15 2015_12 FBgn0069943 CG41098 http://flybase.net/reports/FBgn0069943.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011057 l(1)Q10 lethal (1) Q10 http://flybase.net/reports/FBgn0011057.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0005421 l(1)adl10 lethal (1) adl10 http://flybase.net/reports/FBgn0005421.html gene l(1)adl-10 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0019802 l(1)02 lethal (1) 02 http://flybase.net/reports/FBgn0019802.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033932 Dh44-R1 Diuretic hormone 44 receptor 1 http://flybase.net/reports/FBgn0033932.html "FBgn0046622, FBgn0046623" protein_coding_gene "0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity, 0008036=diuretic hormone receptor activity, 0005184=neuropeptide hormone activity, 0004948=calcitonin receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0009755=hormone-mediated signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "DH44-receptor, DH44 Receptor, anon-WO0170980.100, DmeCG8422, DH44-R1, unnamed, CG8422, DH-R, CRF-like diuretic hormone receptor 1, DH[[44]] receptor, DH[[44]]-R1, anon-WO0170980.101" "IPR002001=GPCR, family 2, diuretic hormone receptor, IPR000832=GPCR, family 2, secretin-like, IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR017981=GPCR, family 2-like" CG8422 16-Dec-15 2015_12 "ENSDARG00000062377,ENSDARG00000003989(crhr1)" "ENSXETG00000005305(CRHR1),ENSXETG00000018502(CRHR2)" "ENSMUSG00000003476(Crhr2),ENSMUSG00000018634(Crhr1)" "ENSG00000106113(CRHR2),ENSG00000120088(CRHR1)" DRSC07172 E -0.357994633 -0.135183574 1.645185021 0.642298972 -0.43604201 -0.101367821 FBgn0053419 5SrRNA:CR33419 5SrRNA:CR33419 http://flybase.net/reports/FBgn0053419.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33419 CR33419 16-Dec-15 2015_12 FBgn0069314 X-195-35 X-195-35 http://flybase.net/reports/FBgn0069314.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0013645 mfs(3)1 mfs(3)1 http://flybase.net/reports/FBgn0013645.html gene 16-Dec-15 2015_12 "male sterile,recessive,female sterile" FBgn0002245 l(3)68Cg lethal (3) 68Cg http://flybase.net/reports/FBgn0002245.html gene "l(3)rsg6, rose-gespleten region interval 6, rsg6" 16-Dec-15 2015_12 lethal FBgn0032666 CG5758 http://flybase.net/reports/FBgn0032666.html protein_coding_gene 0008039=synaptic target recognition IPR000782=FAS1 domain CG5758 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,viable" wing DRSC02889 I -1.071424404 -2.016985346 0.53185522 -0.94514155 0.516841157 0.080887305 FBgn0036973 Rbbp5 Retinoblastoma binding protein 5 http://flybase.net/reports/FBgn0036973.html protein_coding_gene 0051568=histone H3-K4 methylation "0048188=Set1C/COMPASS complex, 0044666=MLL3/4 complex, 0044665=MLL1/2 complex" "rbbp5, dRbbp5, CG5585, RBBP5" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site" CG5585 16-Dec-15 2015_12 ENSDARG00000042147(rbbp5) YAR003W(SWD1) WBGene00017683(F21H12.1) ENSXETG00000000933(rbbp5) ENSMUSG00000026439(Rbbp5) ENSG00000117222(RBBP5) "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,female fertile" mesothoracic tergum FBgn0266467 nut http://flybase.net/reports/FBgn0266467.html gene 16-Dec-15 2015_12 lethal "egg chamber,germline clone" FBgn0015580 4.1 4.1 http://flybase.net/reports/FBgn0015580.html gene 16-Dec-15 2015_12 FBgn0022316 l(1)D36.5 lethal (1) D36.5 http://flybase.net/reports/FBgn0022316.html gene D36.5 16-Dec-15 2015_12 "lethal,recessive" FBgn0021927 l(2)k11120a lethal (2) k11120a http://flybase.net/reports/FBgn0021927.html gene l(2)k11120 16-Dec-15 2015_12 FBgn0051924 CG31924 http://flybase.net/reports/FBgn0051924.html "FBgn0031334, FBgn0063290" protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process "CG5564, 21064207, BcDNA:AT29272" "IPR006439=HAD hydrolase, subfamily IA, IPR023214=HAD-like domain" CG31924 16-Dec-15 2015_12 YKL033W-A() WBGene00020113(R151.10) viable FBgn0065893 l(2)SH0214 lethal (2) SH0214 http://flybase.net/reports/FBgn0065893.html gene l(2)SH2 0214 16-Dec-15 2015_12 "lethal,recessive" FBgn0260434 CG42529 http://flybase.net/reports/FBgn0260434.html protein_coding_gene CG42529 16-Dec-15 2015_12 FBgn0259981 l(2)34Dh lethal (2) 34Dh http://flybase.net/reports/FBgn0259981.html gene 16-Dec-15 2015_12 lethal FBgn0041723 rho-5 rhomboid-5 http://flybase.net/reports/FBgn0041723.html "FBgn0032232, FBgn0053304" protein_coding_gene 0004252=serine-type endopeptidase activity "0030431=sleep, 0042058=regulation of epidermal growth factor receptor signaling pathway, 0007165=signal transduction, 0006508=proteolysis" "0016021=integral component of membrane, 0005783=endoplasmic reticulum" "CG33304, CT17046, Rho-related[31D10], iRhom, CG5364" "IPR022764=Peptidase S54, rhomboid domain, IPR002610=Peptidase S54, rhomboid" CG33304 16-Dec-15 2015_12 "ENSDARG00000017367(LOC563403),ENSDARG00000036541(zgc:91984)" "WBGene00004403(rom-4),WBGene00004402(rom-3)" ENSXETG00000019523(RHBDF2) "ENSMUSG00000020282(Rhbdf1),ENSMUSG00000020806(Rhbdf2)" "viable,sleep defective,recessive,fertile,lethal" FBgn0259459 C933.1 http://flybase.net/reports/FBgn0259459.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta,ectopic" FBgn0060638 l(3)S084307b lethal (3) S084307b http://flybase.net/reports/FBgn0060638.html gene 0843/07 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0036986 CG5282 http://flybase.net/reports/FBgn0036986.html protein_coding_gene 0016805=dipeptidase activity 0006508=proteolysis IPR008257=Renal dipeptidase family CG5282 16-Dec-15 2015_12 viable FBgn0065221 l(2)SH2227 lethal (2) SH2227 http://flybase.net/reports/FBgn0065221.html gene l(2)SH2 2227 16-Dec-15 2015_12 "lethal,recessive" FBgn0065254 l(2)SH2112 lethal (2) SH2112 http://flybase.net/reports/FBgn0065254.html gene l(2)SH2 2112 16-Dec-15 2015_12 "lethal,recessive" FBgn0262546 CR43100 http://flybase.net/reports/FBgn0262546.html pseudogene_attribute CG43100 CR43100 16-Dec-15 2015_12 FBgn0052563 CG32563 http://flybase.net/reports/FBgn0052563.html FBgn0030825 protein_coding_gene CG5095 CG32563 16-Dec-15 2015_12 FBgn0003875 tu(1)Sz tumor (1) Sz http://flybase.net/reports/FBgn0003875.html gene "Tu-Sz, tu-Sz" 16-Dec-15 2015_12 "visible,heat sensitive" FBgn0051047 CG31047 http://flybase.net/reports/FBgn0051047.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001060 Fs(3)Lev Female sterile (3) Levente http://flybase.net/reports/FBgn0001060.html gene 0040016=embryonic cleavage "Lev, Fs(3)Levente, Fs(3)Sz28" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0043888 l(3)C80 lethal (3) C80 http://flybase.net/reports/FBgn0043888.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 "lethal,recessive" FBgn0003684 tetra tetraltera http://flybase.net/reports/FBgn0003684.html gene tet 16-Dec-15 2015_12 "visible,cold sensitive" "wing,mesothoracic tergum,costal vein,wing hinge,ventral" FBgn0003442 sml small http://flybase.net/reports/FBgn0003442.html gene 16-Dec-15 2015_12 "partially lethal - majority die,visible" "eye,ommatidium,wing,adult thorax & microchaeta" FBgn0001814 l(1)nc3 lethal (1) nc3 http://flybase.net/reports/FBgn0001814.html gene l(1)11523 16-Dec-15 2015_12 "lethal,female sterile" FBgn0001441 l(1)7Cc lethal (1) 7Cc http://flybase.net/reports/FBgn0001441.html gene EC271 16-Dec-15 2015_12 lethal FBgn0067914 EP303 EP303 http://flybase.net/reports/FBgn0067914.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0040217 fs(2)LJ25 fs(2)LJ25 http://flybase.net/reports/FBgn0040217.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0037996 CG4830 http://flybase.net/reports/FBgn0037996.html protein_coding_gene "0005324=long-chain fatty acid transporter activity, 0003824=catalytic activity" 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR020845=AMP-binding, conserved site, IPR000873=AMP-dependent synthetase/ligase" CG4830 16-Dec-15 2015_12 viable FBgn0001950 l(2)27Dc lethal (2) 27Dc http://flybase.net/reports/FBgn0001950.html gene "F, Complementation group F" 16-Dec-15 2015_12 lethal FBgn0051029 CG31029 http://flybase.net/reports/FBgn0051029.html "FBgn0039746, FBgn0065016" protein_coding_gene "BcDNA:AT12234, CG2164" CG31029 16-Dec-15 2015_12 viable FBgn0260112 2L2944 http://flybase.net/reports/FBgn0260112.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0051078 CG31078 http://flybase.net/reports/FBgn0051078.html protein_coding_gene 16-Dec-15 2015_12 FBgn0070037 3R-66-38 3R-66-38 http://flybase.net/reports/FBgn0070037.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "filzkorper,germline clone,maternal effect,embryonic head" FBgn0029952 CG12689 http://flybase.net/reports/FBgn0029952.html protein_coding_gene CG12689 16-Dec-15 2015_12 viable FBgn0004139 l(2)43Eh lethal (2) 43Eh http://flybase.net/reports/FBgn0004139.html gene 16-Dec-15 2015_12 lethal FBgn0044084 E(rst)H125 E(rst)H125 http://flybase.net/reports/FBgn0044084.html gene 0001745=compound eye morphogenesis H125 16-Dec-15 2015_12 viable eye FBgn0267283 CR45719 http://flybase.net/reports/FBgn0267283.html non_protein_coding_gene CR45719 16-Dec-15 2015_12 FBgn0065648 l(2)SH0742 lethal (2) SH0742 http://flybase.net/reports/FBgn0065648.html gene l(2)SH2 0742 16-Dec-15 2015_12 "lethal,recessive" FBgn0028001 l(3)S119715 lethal (3) S119715 http://flybase.net/reports/FBgn0028001.html gene 1197/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0004408 tnk tonock http://flybase.net/reports/FBgn0004408.html gene 16-Dec-15 2015_12 FBgn0085257 CG34228 http://flybase.net/reports/FBgn0085257.html protein_coding_gene HDC05827 CG34228 16-Dec-15 2015_12 ENSDARG00000070358(zgc:103571) ENSXETG00000016486(TGas122k06.1) ENSMUSG00000042380(BC003266) FBgn0004844 l(3)88Bb lethal (3) 88Bb http://flybase.net/reports/FBgn0004844.html gene l(3)Z4 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0040964 CG18661 http://flybase.net/reports/FBgn0040964.html FBgn0062870 protein_coding_gene BcDNA:SD17344 "IPR010342=Protein of unknown function DUF938, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG18661 16-Dec-15 2015_12 "ENSDARG00000027461(zgc:56719),ENSDARG00000038770(LOC100149816)" WBGene00012514(Y26E6A.3) ENSXETG00000020260() ENSMUSG00000025731(0610011F06Rik) ENSG00000130731(C16orf13) "viable,fertile" FBgn0034462 CG15905 http://flybase.net/reports/FBgn0034462.html protein_coding_gene CG15905 16-Dec-15 2015_12 "viable,fertile" FBgn0065856 l(2)SH0294 lethal (2) SH0294 http://flybase.net/reports/FBgn0065856.html gene l(2)SH2 0294 16-Dec-15 2015_12 "lethal,recessive" FBgn0036549 CG10516 http://flybase.net/reports/FBgn0036549.html protein_coding_gene "IPR001870=B30.2/SPRY domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR003877=SPRY domain" CG10516 16-Dec-15 2015_12 ENSXETG00000010355(TGas007f05.1) ENSMUSG00000024160(Spsb3) ENSG00000162032(SPSB3) "viable,fertile" FBgn0052341 CG32341 http://flybase.net/reports/FBgn0052341.html FBgn0046993 protein_coding_gene BcDNA:SD01284 16-Dec-15 2015_12 FBgn0028522 BG:DS03192.3 BG:DS03192.3 http://flybase.net/reports/FBgn0028522.html gene "DS03192.3, DS003192.3" 16-Dec-15 2015_12 FBgn0001273 irreD irregular optic chiasma D http://flybase.net/reports/FBgn0001273.html gene 16-Dec-15 2015_12 FBgn0263340 CR43421 http://flybase.net/reports/FBgn0263340.html non_protein_coding_gene CR43421 16-Dec-15 2015_12 FBgn0054028 CG34028 http://flybase.net/reports/FBgn0054028.html FBgn0082832 protein_coding_gene "unnamed, BP1074" IPR010512=Protein of unknown function DUF1091 CG34028 16-Dec-15 2015_12 FBgn0054045 CG34045 http://flybase.net/reports/FBgn0054045.html FBgn0082897 protein_coding_gene "BP1009, unnamed" CG34045 16-Dec-15 2015_12 FBgn0030375 CG11356 http://flybase.net/reports/FBgn0030375.html protein_coding_gene 0005525=GTP binding Arl13b "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG11356 16-Dec-15 2015_12 viable FBgn0266380 CR45022 http://flybase.net/reports/FBgn0266380.html non_protein_coding_gene CR45022 16-Dec-15 2015_12 FBgn0030696 CG8509 http://flybase.net/reports/FBgn0030696.html protein_coding_gene 0008160=protein tyrosine phosphatase activator activity "IPR004327=Phosphotyrosyl phosphatase activator, PTPA" CG8509 16-Dec-15 2015_12 viable DRSC20109 E -0.608331785 0.291037045 -1.814245608 -0.848802594 0.347951259 0.167287887 FBgn0085608 CG41312 http://flybase.net/reports/FBgn0085608.html FBan0041312 protein_coding_gene 16-Dec-15 2015_12 FBgn0050381 CG30381 http://flybase.net/reports/FBgn0050381.html protein_coding_gene 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane "IPR013233=Glycosylphosphatidylinositol-mannosyltransferase I, PIG-X/PBN1" CG30381 16-Dec-15 2015_12 ENSDARG00000063559(pigx) ENSG00000163964(PIGX) viable FBgn0038915 CG17819 http://flybase.net/reports/FBgn0038915.html FBgn0063100 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0006471=protein ADP-ribosylation, 0007264=small GTPase mediated signal transduction" 0005622=intracellular BcDNA:LP07781 "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR024156=Small GTPase superfamily, ARF type" CG17819 16-Dec-15 2015_12 viable FBgn0000054 Adf1 Adh transcription factor 1 http://flybase.net/reports/FBgn0000054.html "FBgn0010484, FBgn0010565, FBgn0013714, FBgn0033084" protein_coding_gene "0003677=DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0007416=synapse assembly, 0045893=positive regulation of transcription, DNA-templated, 0007613=memory, 0007616=long-term memory, 0006357=regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007611=learning or memory, 0050773=regulation of dendrite development, 0008345=larval locomotory behavior, 0040011=locomotion, 0008355=olfactory learning" "0005705=polytene chromosome interband, 0005634=nucleus" "l(2)01349, Nalyot, Adh transcription factor 1, nal, l(2)04065, Adf 1, adf1, Adf-1, adf-1, CG15845, naylot, nalyot" "IPR004210=BESS motif, IPR006578=MADF domain" CG15845 16-Dec-15 2015_12 embryonic stage | >4 hr

ubiquitous "lethal,recessive,visible,neuroanatomy defective,partially lethal - majority die,memory defective,somatic clone,neurophysiology defective,locomotor behavior defective,wild-type,viable" "scutellar bristle,ectopic,dorsocentral bristle,intersegmental nerve,anterior fascicle & synapse,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,RP2 motor neuron,dendrite,bouton,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,somatic clone" DRSC04941 IE -0.551396565 2.612898087 -0.89456857 1.630279999 -0.23039804 0.373370956 FBgn0017435 anon-28Cd anon-28Cd http://flybase.net/reports/FBgn0017435.html gene unnamed 16-Dec-15 2015_12 FBgn0085331 CG34302 http://flybase.net/reports/FBgn0085331.html protein_coding_gene CG34302 16-Dec-15 2015_12 FBgn0029701 CG12691 http://flybase.net/reports/FBgn0029701.html protein_coding_gene CG12691 16-Dec-15 2015_12 viable FBgn0030854 CG8289 http://flybase.net/reports/FBgn0030854.html protein_coding_gene "IPR023780=Chromo domain, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like" CG8289 16-Dec-15 2015_12 "viable,fertile" FBgn0266393 CR45033 http://flybase.net/reports/FBgn0266393.html pseudogene_attribute CR31541 CR45033 16-Dec-15 2015_12 FBgn0259716 CG42370 http://flybase.net/reports/FBgn0259716.html "FBgn0031810, FBgn0031809, FBan0009511" protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "CG33295, CG13981, Dmel_CG42370, CG9508, CT26920, CG9511" "IPR000718=Peptidase M13, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR008753=Peptidase M13, N-terminal domain" CG42370 16-Dec-15 2015_12 viable FBgn0003542 stt spotty http://flybase.net/reports/FBgn0003542.html gene 16-Dec-15 2015_12 "viable,male,reduced,male sterile,visible,body color defective" "wing,adult abdomen,microchaeta,eye,macrochaeta,tergite" FBgn0016677 Mab13D2 Monoclonal antibody 13D2 http://flybase.net/reports/FBgn0016677.html gene 16-Dec-15 2015_12 FBgn0001321 knk knickkopf http://flybase.net/reports/FBgn0001321.html "FBgn0037790, FBgn0042639" protein_coding_gene "0035152=regulation of tube architecture, open tracheal system, 0007362=terminal region determination, 0008293=torso signaling pathway, 0006031=chitin biosynthetic process, 0007424=open tracheal system development, 0060439=trachea morphogenesis, 0040003=chitin-based cuticle development, 0006035=cuticle chitin biosynthetic process, 0008362=chitin-based embryonic cuticle biosynthetic process, 0035151=regulation of tube size, open tracheal system, 0001838=embryonic epithelial tube formation, 0035158=regulation of tube diameter, open tracheal system" "l(3)85Eg, gnarled, gnar, dyspneic, Gnarled, CG6217, Knk, Knickkopf" "IPR019545=DM13 domain, IPR005018=DOMON domain" CG6217 16-Dec-15 2015_12 WBGene00020921(W01C8.5) "lethal,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,tracheal system,denticle belt,cephalopharyngeal skeleton,wing hair,somatic clone,epicuticle,procuticle,presumptive embryonic/larval tracheal system,embryonic/larval cuticle,larval head,vertical bridge,embryonic/first instar larval cuticle,terminal tracheal cell,eye" FBgn0027209 l(1)G0363 lethal (1) G0363 http://flybase.net/reports/FBgn0027209.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,viable" FBgn0266811 CR45273 http://flybase.net/reports/FBgn0266811.html non_protein_coding_gene CR45273 16-Dec-15 2015_12 FBgn0003338 scruff scruff http://flybase.net/reports/FBgn0003338.html gene scr 16-Dec-15 2015_12 visible "macrochaeta,microchaeta,wing,scutellum" FBgn0036859 CG14085 http://flybase.net/reports/FBgn0036859.html protein_coding_gene IPR027993=Protein of unknown function DUF4495 CG14085 16-Dec-15 2015_12 ENSMUSG00000071252 viable FBgn0028294 l(1)G0392 lethal (1) G0392 http://flybase.net/reports/FBgn0028294.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061094 l(3)S010917b lethal (3) S010917b http://flybase.net/reports/FBgn0061094.html gene 0109/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0028019 l(3)S104115 lethal (3) S104115 http://flybase.net/reports/FBgn0028019.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259676 DNApol-ë±60 DNA polymerase ë± 60kD http://flybase.net/reports/FBgn0259676.html "FBgn0028834, FBgn0011425, FBgn0027911" protein_coding_gene "0003896=DNA primase activity, 0003887=DNA-directed DNA polymerase activity" "0006260=DNA replication, 0000278=mitotic cell cycle, 0006261=DNA-dependent DNA replication, 0006269=DNA replication, synthesis of RNA primer" "0005634=nucleus, 0005658=alpha DNA polymerase:primase complex" "Dmpol alpha, GM13640, DNAprimase, pol alpha, DNA primase, S(faf)240, polalpha, Pol, Polalpha 60 kDa, DNA polymerase alpha 58,000 beta subunit, DNA polymerase alpha 60,000 beta subunit, l(3)77ABe, BcDNA:GM13640, DNA polymerase alpha 60kD, DNAprim, l(3)j10B2, CG5553, DNA replication primer, DNA polalpha" "IPR016558=DNA primase, large subunit, eukaryotic, IPR007238=DNA primase large subunit, eukaryotic/archaeal" CG5553 16-Dec-15 2015_12 ENSDARG00000052721(zgc:110727) YKL045W(PRI2) WBGene00004181(pri-2) ENSXETG00000004450(PRIM2) ENSMUSG00000026134(Prim2) ENSG00000146143 DRSC11610 I 1.847159061 -1.133336803 0.47019141 -0.214543402 -0.099671186 0.284626687 FBgn0014040 Su(tor)1-163 Su(tor)1-163 http://flybase.net/reports/FBgn0014040.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0262515 VhaAC45 Vacuolar H+ ATPase AC45 accessory subunit http://flybase.net/reports/FBgn0262515.html "FBgn0033393, FBgn0062233, FBgn0065388" protein_coding_gene "0046933=proton-transporting ATP synthase activity, rotational mechanism, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033180=proton-transporting V-type ATPase, V1 domain, 0033181=plasma membrane proton-transporting V-type ATPase complex" "l(2)SH1634, CG8029, l(2)SH2 1634, vhaAC45, Vacuolar H[+] ATPase accessory protein AC45, lethal (2) SH1634, anon-WO0118547.117" "IPR008388=ATPase, V1 complex, subunit S1" CG8029 16-Dec-15 2015_12 "ENSDARG00000037153(atp6ap1),ENSDARG00000041417(si:ch211-117k14.5)" WBGene00021952(vha-19) ENSXETG00000003377(ATP6AP1) ENSMUSG00000019087(Atp6ap1) "lethal,recessive" FBgn0010387 Dbi Diazepam-binding inhibitor http://flybase.net/reports/FBgn0010387.html "FBgn0046463, FBgn0047016" protein_coding_gene "0004857=enzyme inhibitor activity, 0000062=fatty-acyl-CoA binding, 0050809=diazepam binding" 0042049=cellular acyl-CoA homeostasis "BcDNA:RH39533, acyl-CoA binding protein, anon-WO0172774.131, dbi, ACBP, CG8627, DBI, diazepam binding inhibitor, diazepam-binding protein, endozepine" "IPR022408=Acyl-CoA-binding protein, ACBP, conserved site, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000582=Acyl-CoA-binding protein, ACBP" CG8627 16-Dec-15 2015_12 YGR037C(ACB1) WBGene00016655(acbp-1) viable DRSC24352 K -0.367557499 0.742422986 -0.36955077 -0.053065981 0.614965637 1.748198619 FBgn0053438 5SrRNA:CR33438 5SrRNA:CR33438 http://flybase.net/reports/FBgn0053438.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33438 CR33438 16-Dec-15 2015_12 FBgn0003579 Su(SD)X Suppressor of SD on the X http://flybase.net/reports/FBgn0003579.html gene "supp-X(SD), su(SD), suppressor of Segregation Distortion, Su(SD)" 16-Dec-15 2015_12 FBgn0263868 CR43715 http://flybase.net/reports/FBgn0263868.html non_protein_coding_gene lincRNA.47 CR43715 16-Dec-15 2015_12 FBgn0054002 CG34002 http://flybase.net/reports/FBgn0054002.html FBgn0082881 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "MIP08535, unnamed, BP1025" "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG34002 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00016821(scl-26),WBGene00011841(scl-25),WBGene00008575(scl-24),WBGene00022638(scl-27)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" DRSC26854 K -0.218804284 0.644771968 0.094639444 -0.529151718 -0.130708552 -1.507416894 FBgn0001312 kl-1 male fertility factor kl1 http://flybase.net/reports/FBgn0001312.html gene Lms1 16-Dec-15 2015_12 male sterile FBgn0038217 CG14840 http://flybase.net/reports/FBgn0038217.html protein_coding_gene 0022008=neurogenesis IPR007999=Protein of unknown function DUF745 CG14840 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0052503 CG32503 http://flybase.net/reports/FBgn0052503.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030878 CG6769 http://flybase.net/reports/FBgn0030878.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "IPR007087=Zinc finger, C2H2, IPR003604=Zinc finger, U1-type, IPR015880=Zinc finger, C2H2-like, IPR022755=Zinc finger, double-stranded RNA binding" CG6769 16-Dec-15 2015_12 ENSDARG00000014692(znf622) "YBR267W(REI1),YLR387C(REH1)" WBGene00015809(C16A3.4) ENSXETG00000007539(znf622) ENSMUSG00000052253(Zfp622) ENSG00000173545(ZNF622) "lethal,recessive" FBgn0038295 Gyc88E Guanylyl cyclase at 88E http://flybase.net/reports/FBgn0038295.html protein_coding_gene "0070025=carbon monoxide binding, 0019826=oxygen sensor activity, 0070026=nitric oxide binding, 0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0004383=guanylate cyclase activity, 0019825=oxygen binding, 0020037=heme binding" "0000302=response to reactive oxygen species, 0001666=response to hypoxia, 0006182=cGMP biosynthetic process, 0035556=intracellular signal transduction" "0008074=guanylate cyclase complex, soluble" "GYC, CG4154, Gyc-88E" "IPR011644=Heme-NO binding, IPR011645=Haem NO binding associated, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR024096=NO signalling/Golgi transport ligand-binding domain" CG4154 16-Dec-15 2015_12 WBGene00001551(gcy-31) "stress response defective,viable,taste perception defective" FBgn0266415 CR45055 http://flybase.net/reports/FBgn0266415.html non_protein_coding_gene CR45055 16-Dec-15 2015_12 FBgn0028247 l(3)M256 lethal (3) M256 http://flybase.net/reports/FBgn0028247.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0064185 f::nec f::nec http://flybase.net/reports/FBgn0064185.html engineered_fusion_gene 16-Dec-15 2015_12 melanotic necrosis "wing hair,chaeta" FBgn0053413 5SrRNA:CR33413 5SrRNA:CR33413 http://flybase.net/reports/FBgn0053413.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33413 CR33413 16-Dec-15 2015_12 FBgn0052017 CG32017 http://flybase.net/reports/FBgn0052017.html protein_coding_gene CG32017 16-Dec-15 2015_12 viable FBgn0039612 CG14523 http://flybase.net/reports/FBgn0039612.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain" CG14523 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0040600 CG13631 http://flybase.net/reports/FBgn0040600.html FBgn0064962 protein_coding_gene BcDNA:GH19356 CG13631 16-Dec-15 2015_12 viable FBgn0034461 CG15124 http://flybase.net/reports/FBgn0034461.html protein_coding_gene CG15124 16-Dec-15 2015_12 viable FBgn0053535 tRNA:CR33535 transfer RNA:CR33535 http://flybase.net/reports/FBgn0053535.html FBgn0060238 tRNA_gene "0033459=GAA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR33535, AE002787.trna8-GluTTC, chr2R.trna66-GluTTC, tRNA:E:TTC:AE002787-d" CR33535 16-Dec-15 2015_12 FBgn0040893 CG14774 http://flybase.net/reports/FBgn0040893.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003613 Su(var)2-11 Suppressor of variegation 2-11 http://flybase.net/reports/FBgn0003613.html gene Su-var(2)11 16-Dec-15 2015_12 "female sterile,recessive,suppressor of variegation,dominant" FBgn0037660 beag beag http://flybase.net/reports/FBgn0037660.html protein_coding_gene "0000398=mRNA splicing, via spliceosome, 0007274=neuromuscular synaptic transmission, 0072553=terminal button organization, 0007528=neuromuscular junction development" "0071011=precatalytic spliceosome, 0005634=nucleus, 0071013=catalytic step 2 spliceosome" CG18005 "IPR012916=RED-like, N-terminal, IPR012492=Protein RED, C-terminal" CG18005 16-Dec-15 2015_12 ENSDARG00000004161(ik) WBGene00004896(smu-2) ENSXETG00000016509(IK) ENSMUSG00000024474(Ik) ENSG00000113141(IK) "partially lethal - majority die,neuroanatomy defective,neurophysiology defective,viable,planar polarity defective" "NMJ bouton,germline cell,male" FBgn0031876 Atac1 Ada2a-containing complex component 1 http://flybase.net/reports/FBgn0031876.html protein_coding_gene "0004402=histone acetyltransferase activity, 0003677=DNA binding" "0006338=chromatin remodeling, 0043966=histone H3 acetylation, 0043967=histone H4 acetylation, 0016573=histone acetylation" 0005671=Ada2/Gcn5/Ada3 transcription activator complex "ATAC component 1, CG9200, dATAC1" "IPR009057=Homeodomain-like, IPR001005=SANT/Myb domain" CG9200 16-Dec-15 2015_12 viable FBgn0261397 didum dilute class unconventional myosin http://flybase.net/reports/FBgn0261397.html "FBgn0069080, FBgn0015933, FBgn0023490, FBgn0045305" protein_coding_gene "0005524=ATP binding, 0032027=myosin light chain binding, 0003779=actin binding, 0042623=ATPase activity, coupled, 0003774=motor activity, 0051015=actin filament binding, 0005516=calmodulin binding, 0030898=actin-dependent ATPase activity" "0047497=mitochondrion transport along microtubule, 0008595=anterior/posterior axis specification, embryo, 0007291=sperm individualization, 0045856=positive regulation of pole plasm oskar mRNA localization, 0030048=actin filament-based movement, 0006886=intracellular protein transport, 0048477=oogenesis, 0042052=rhabdomere development" "0043025=neuronal cell body, 0031475=myosin V complex, 0016459=myosin complex, 0016028=rhabdomere" "soy, MYOV, shorty, NEST:bs14c05, myosin V, Myosin V, MyosinV, M5, CG2146, unnamed, Myo5, 43CD, MyoV43CD, NMC7, myosin-V, DmV, myoV, MyoV, Didum" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000048=IQ motif, EF-hand binding site, IPR002710=Dilute domain, IPR001609=Myosin head, motor domain, IPR008989=Myosin S1 fragment, N-terminal" CG2146 16-Dec-15 2015_12 "ENSDARG00000061635(myo5a),ENSDARG00000062003(myo5b),ENSDARG00000025218(im:7152131),ENSDARG00000013782(LOC562676)" "YOR326W(MYO2),YAL029C(MYO4)" WBGene00002036(hum-2) "ENSMUSG00000034593(Myo5a),ENSMUSG00000025885(Myo5b),ENSMUSG00000033590(Myo5c)" "ENSG00000197535(MYO5A),ENSG00000167306(MYO5B),ENSG00000128833(MYO5C)" " embryonic stage | stage 1-6 , adult stage | female , adult stage && oogenesis stage | stage S6-8 , embryonic stage , adult stage | male , adult stage && oogenesis stage | stage >S9 , adult stage && oogenesis stage , embryonic stage | stage 16 , embryonic stage && adult stage " "

ubiquitous , ovary

, oocyte | anterior

, testis

, nurse cell

, oocyte

, embryonic/larval hindgut

" FBgn0262537 CG43091 http://flybase.net/reports/FBgn0262537.html protein_coding_gene CG43091 16-Dec-15 2015_12 FBgn0065712 l(2)SH0586 lethal (2) SH0586 http://flybase.net/reports/FBgn0065712.html gene l(2)SH2 0586 16-Dec-15 2015_12 "lethal,recessive" FBgn0032809 CG13078 http://flybase.net/reports/FBgn0032809.html protein_coding_gene 0016021=integral component of membrane "IPR006593=Cytochrome b561/ferric reductase transmembrane, IPR004877=Cytochrome b561 domain" CG13078 16-Dec-15 2015_12 "ENSDARG00000044114(cyb561d2),ENSDARG00000055295(cyb561d1)" ENSXETG00000025206(Cyb561d2) "ENSG00000174151(CYB561D1),ENSG00000114395(CYB561D2)" viable FBgn0005658 Ets65A Ets at 65A http://flybase.net/reports/FBgn0005658.html "FBgn0035681, FBgn0040840" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Ets, CG6882, D-ets-3, ETS3, CG7018, Ets3, ets65A, CG13294, D-Ets-3" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain" CG7018 16-Dec-15 2015_12 "ENSDARG00000044511(LOC100332865),ENSDARG00000069763(etv5a),ENSDARG00000018303(pea3),ENSDARG00000055183(etv1)" "ENSXETG00000023717(ERG),ENSXETG00000022780(FLI1)" "ENSMUSG00000040732(Erg),ENSMUSG00000016087(Fli1)" "ENSG00000157554(ERG),ENSG00000151702(FLI1)" embryonic stage ventral nerve cord

viable FBgn0016699 R2-element\ORF ORF http://flybase.net/reports/FBgn0016699.html transposable_element_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0015074=DNA integration "R2 ORF, RT, R2, R2Dm RTase, R2Dm ORF" "IPR009882=Gypsy, IPR015880=Zinc finger, C2H2-like, IPR000477=Reverse transcriptase domain, IPR012337=Ribonuclease H-like domain, IPR007087=Zinc finger, C2H2, IPR001584=Integrase, catalytic core" 16-Dec-15 2015_12 FBgn0003382 sha shavenoid http://flybase.net/reports/FBgn0003382.html "FBgn0025509, FBgn0033618" protein_coding_gene "0035317=imaginal disc-derived wing hair organization, 0009913=epidermal cell differentiation, 0035316=non-sensory hair organization, 0035017=cuticle pattern formation, 0048800=antennal morphogenesis" 0005938=cell cortex "CG13209, lincRNA.286, shavenoid/kojak, koj, kojak" CG13209 16-Dec-15 2015_12 "visible,flightless,viable,somatic clone,flight defective,heat sensitive,recessive,partially lethal - majority die" "arista,trichome,denticle belt,3rd posterior cell | dorsal & wing hair | supernumerary,mesothoracic tergum & trichome,adult abdomen & trichome,dorsal denticle,wing hair,somatic clone,denticle,dorsal hair,embryonic/larval cuticle,heat sensitive,3rd posterior cell | dorsal & wing hair,3rd posterior cell | dorsal & wing hair | somatic clone,1st posterior cell | ventral & wing hair" FBgn0250874 ttm50 tiny tim 50 http://flybase.net/reports/FBgn0250874.html "FBgn0024978, FBgn0020428" protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0006470=protein dephosphorylation, 0015031=protein transport, 0007005=mitochondrion organization, 0007067=mitotic nuclear division, 0007006=mitochondrial membrane organization" "0005744=mitochondrial inner membrane presequence translocase complex, 0005739=mitochondrion, 0005743=mitochondrial inner membrane" "17944223, EG:95B7.3, i90, CG2713, Gp99, i238" "IPR023214=HAD-like domain, IPR027111=Mitochondrial import inner membrane translocase subunit Tim50, IPR004274=FCP1 homology domain" CG2713 16-Dec-15 2015_12 ENSDARG00000031098(timm50) YPL063W(TIM50) WBGene00011897(scpl-4) ENSXETG00000002882(TIMM50) ENSMUSG00000003438(Timm50) ENSG00000105197(TIMM50) DRSC18587 E -0.090070767 -0.460557644 -1.69496571 0.018321583 -0.496976442 -0.132459427 FBgn0069170 mcl(3)Z0684 mcl(3)Z0684 http://flybase.net/reports/FBgn0069170.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0021982 l(2)k09903 lethal (2) k09903 http://flybase.net/reports/FBgn0021982.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060587 l(3)S093806b lethal (3) S093806b http://flybase.net/reports/FBgn0060587.html gene 0938/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0002421 l(3)F12 lethal (3) F12 http://flybase.net/reports/FBgn0002421.html gene l(3)12 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0027352 anon-93Ba anon-93Ba http://flybase.net/reports/FBgn0027352.html gene 16-Dec-15 2015_12 FBgn0022370 Pt-37 Adult protein-37 http://flybase.net/reports/FBgn0022370.html gene 16-Dec-15 2015_12 FBgn0031689 Cyp28d1 Cyp28d1 http://flybase.net/reports/FBgn0031689.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "cytochrome P450, CG10833, 28d1" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG10833 16-Dec-15 2015_12 YHR007C(ERG11) viable FBgn0265702 CR44509 http://flybase.net/reports/FBgn0265702.html non_protein_coding_gene CR44509 16-Dec-15 2015_12 FBgn0263864 Dark Death-associated APAF1-related killer http://flybase.net/reports/FBgn0263864.html "FBgn0065914, FBgn0024252, FBgn0028733" protein_coding_gene "0005524=ATP binding, 0050700=CARD domain binding, 0008656=cysteine-type endopeptidase activator activity involved in apoptotic process, 0097199=cysteine-type endopeptidase activity involved in apoptotic signaling pathway, 0043531=ADP binding" "0007291=sperm individualization, 0035006=melanization defense response, 0070050=neuron cellular homeostasis, 0051260=protein homooligomerization, 0051291=protein heterooligomerization, 0043065=positive regulation of apoptotic process, 0012501=programmed cell death, 0021556=central nervous system formation, 0008635=activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, 0046672=positive regulation of compound eye retinal cell programmed cell death, 0033353=S-adenosylmethionine cycle, 0034352=positive regulation of glial cell apoptotic process, 0006915=apoptotic process, 0070328=triglyceride homeostasis, 0046668=regulation of retinal cell programmed cell death, 0048813=dendrite morphogenesis, 0035070=salivary gland histolysis, 0007423=sensory organ development, 0035071=salivary gland cell autophagic cell death, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0002921=negative regulation of humoral immune response, 0042594=response to starvation, 0010332=response to gamma radiation, 0007559=histolysis, 1901053=sarcosine catabolic process" 0043293=apoptosome "arc, Apaf-1-related killer, Transcription unit 1, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, Apaf-1 related, dark/hac-1/dapaf-1, dAPAF-1, APAF1, Dark/Apaf-I, ARK, l(2)SH0173, apaf1, Apaf-1-Related Killer, Hac1, Apaf1, Hac-1/Dark, Dark/Hac-1/dApaf1, apaf1-related killer, dark/dapaf-1/hac-1, dArk, ark, hac-1, anon-53Fa, D-Apaf-1, dark, Apaf-1 related killer, dApaf-1, dapaf-1L, Ark, dapaf-1S, Dapaf-1, T1, hac1, dApaf-1/DARK/HAC-1, Dapaf-1/HAC-1, Apaf-1-related-killer, dApaf1, Apaf-1, Dark, APAF-1, DARK, dapaf, Drosophila Apaf-1-related killer, lethal (2) SH0173, apaf-1, Hac-1, CG6829, dapaf-1, Apaf" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR002182=NB-ARC, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6829 16-Dec-15 2015_12 ENSDARG00000021239(apaf1) ENSXETG00000006695(APAF1) ENSMUSG00000019979(Apaf1) ENSG00000120868(APAF1) " embryonic stage | stage 7 , embryonic stage | stage 10-11 , embryonic stage , larval stage | third instar , embryonic stage -- adult stage , embryonic stage&&larval stage&&pupal stage , embryonic stage | early " " anterior transverse furrow && cephalic furrow && posterior transverse furrow && ventral furrow

, procephalic neurogenic region

, eye disc

,

ubiquitous , head mesoderm

, ventral neurogenic region

, dorsal mesothoracic disc

" FBgn0264819 CR44027 http://flybase.net/reports/FBgn0264819.html non_protein_coding_gene CR44027 16-Dec-15 2015_12 FBgn0003332 sch slender chaetae http://flybase.net/reports/FBgn0003332.html gene 16-Dec-15 2015_12 "visible,viable,fertile,eye color defective" "pigment cell,macrochaeta,eye" FBgn0025111 Ant2 Adenine nucleotide translocase 2 http://flybase.net/reports/FBgn0025111.html "FBgn0027300, FBgn0028338, FBgn0040166, FBgn0064129" protein_coding_gene "0022857=transmembrane transporter activity, 0005471=ATP:ADP antiporter activity" "0006839=mitochondrial transport, 0015867=ATP transport, 0055085=transmembrane transport, 0015866=ADP transport" "0005811=lipid particle, 0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "l(1)G0247, unnamed, ADP/ATP translocase 2, CG1683, ADP/ATP translocase, ANT2, l(1)G0386, l(1)G0126" "IPR002067=Mitochondrial carrier protein, IPR018108=Mitochondrial substrate/solute carrier, IPR002113=Adenine nucleotide translocator 1, IPR023395=Mitochondrial carrier domain" CG1683 16-Dec-15 2015_12 "YBL030C(PET9),YBR085W(AAC3),YMR056C(AAC1)" "WBGene00020140(ant-1.4),WBGene00010485(ant-1.3),WBGene00006439(ant-1.1),WBGene00007057(ant-1.2)" adult stage "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,some die during pupal stage" DRSC19330 E -0.14910592 -0.718609089 -2.38946575 -0.372629741 -0.741777163 0.286176349 FBgn0000729 fs(1)5e female sterile (1) 5e http://flybase.net/reports/FBgn0000729.html gene 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive,male fertile" FBgn0025144 ms(3)A3 ms(3)A3 http://flybase.net/reports/FBgn0025144.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0016959 tilP touch insensitive larva P http://flybase.net/reports/FBgn0016959.html gene line 78 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0265934 CR44723 http://flybase.net/reports/FBgn0265934.html non_protein_coding_gene lincRNA.509 CR44723 16-Dec-15 2015_12 FBgn0083232 EP718 EP718 http://flybase.net/reports/FBgn0083232.html gene 16-Dec-15 2015_12 FBgn0062541 Juan\pol pol http://flybase.net/reports/FBgn0062541.html transposable_element_gene "Strider\pol, strider ORF2, pol" "IPR000477=Reverse transcriptase domain, IPR005135=Endonuclease/exonuclease/phosphatase" 16-Dec-15 2015_12 FBgn0026245 fph fast phase http://flybase.net/reports/FBgn0026245.html gene 16-Dec-15 2015_12 FBgn0066074 Su(rux)2C Su(rux)2C http://flybase.net/reports/FBgn0066074.html gene 0016330=second mitotic wave involved in compound eye morphogenesis 16-Dec-15 2015_12 FBgn0000051 ade1 adenosine 1 http://flybase.net/reports/FBgn0000051.html gene "ade1-1[sd], ade1-1" 16-Dec-15 2015_12 "auxotroph,recessive" FBgn0040859 CR32658 http://flybase.net/reports/FBgn0040859.html non_protein_coding_gene CG11358 CR32658 16-Dec-15 2015_12 FBgn0001722 l(1)ESHS43 lethal (1) ESHS43 http://flybase.net/reports/FBgn0001722.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033850 CG13331 http://flybase.net/reports/FBgn0033850.html protein_coding_gene CG13331 16-Dec-15 2015_12 viable FBgn0070038 3R-64-33 3R-64-33 http://flybase.net/reports/FBgn0070038.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0262220 mir-987 mir-987 stem loop http://flybase.net/reports/FBgn0262220.html miRNA_gene 0046716=muscle cell cellular homeostasis "CR42927, miR-987, dme-miR-987, dme-mir-987" CR42927 16-Dec-15 2015_12 "viable,visible" "wing,wing vein" FBgn0051848 CG31848 http://flybase.net/reports/FBgn0051848.html protein_coding_gene CG31848 16-Dec-15 2015_12 lethal FBgn0040726 dpr1 defective proboscis extension response 1 http://flybase.net/reports/FBgn0040726.html protein_coding_gene "0050914=sensory perception of salty taste, 0035199=salt aversion" "0005886=plasma membrane, 0016021=integral component of membrane" "CG13439, dpr, dpr1, Dpr1, Dpr-1, DPR1, defective proboscis extension response" "IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG13439 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) "taste perception defective,recessive,viable" FBgn0267441 CR45791 http://flybase.net/reports/FBgn0267441.html non_protein_coding_gene CR45791 16-Dec-15 2015_12 FBgn0044086 E(rst)F84 E(rst)F84 http://flybase.net/reports/FBgn0044086.html gene 0001745=compound eye morphogenesis F84 16-Dec-15 2015_12 viable eye FBgn0066363 ikar ikar http://flybase.net/reports/FBgn0066363.html gene "0008355=olfactory learning, 0007611=learning or memory, 0048149=behavioral response to ethanol" 16-Dec-15 2015_12 "learning defective,memory defective,chemical sensitive" FBgn0036985 zye zye http://flybase.net/reports/FBgn0036985.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0003383=apical constriction, 0016476=regulation of embryonic cell shape, 0007015=actin filament organization, 0007160=cell-matrix adhesion" 0016324=apical plasma membrane "zye, CG5847" IPR001507=Zona pellucida domain CG5847 16-Dec-15 2015_12 viable denticle FBgn0020567 anon-88Ac anon-88Ac http://flybase.net/reports/FBgn0020567.html gene unnamed 16-Dec-15 2015_12 FBgn0000604 E(var)303 Enhancer of variegation 303 http://flybase.net/reports/FBgn0000604.html gene En(var)303 16-Dec-15 2015_12 "viable,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0267060 CR45504 http://flybase.net/reports/FBgn0267060.html non_protein_coding_gene CR45504 16-Dec-15 2015_12 FBgn0013276 Hsp70Ab Heat-shock-protein-70Ab http://flybase.net/reports/FBgn0013276.html "FBgn0001231, FBgn0042100" protein_coding_gene "0009408=response to heat, 0035080=heat shock-mediated polytene chromosome puffing, 0001666=response to hypoxia" 0005875=microtubule associated complex "hsp70A, Hsp70-Ab, Dm-hsp70, Hsp70b, DMHSP7A2, hsp70 87A, hsp-70, Hsp70A, Hsp70ab, heat shock 70, hsp70Ab, dHsp70, heat shock protein 70AB, heat shock protein 70, HSP70Ab, Heat shock protein 70Ab, HSP70, 87A locus, GRP78, heat-shock protein 70, Protein 70, CG18743, Hsp70aB, hsp70(87A), Hsp-70, hsp70, hsp70a, dhsp70, Hsp 70, Hsp70, hsp 70, hs70" "IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site, IPR013126=Heat shock protein 70 family" CG18743 16-Dec-15 2015_12 FBgn0082670 GS1061 GS1061 http://flybase.net/reports/FBgn0082670.html gene 16-Dec-15 2015_12 FBgn0062943 CR32769 http://flybase.net/reports/FBgn0062943.html FBgn0052769 non_protein_coding_gene BcDNA:RH39175 16-Dec-15 2015_12 FBgn0030770 CG13010 http://flybase.net/reports/FBgn0030770.html protein_coding_gene CG13010 16-Dec-15 2015_12 viable FBgn0262419 mir-277 mir-277 stem loop http://flybase.net/reports/FBgn0262419.html "FBgn0067715, FBgn0262261" miRNA_gene "1901216=positive regulation of neuron death, 0035195=gene silencing by miRNA" "dme-miR-277-5p, CR42968, dme-mir-277, Dme-miR-277, miR-277, mir-277, miR277, CR33588, MiR-277" CR42968 16-Dec-15 2015_12 "viable,short lived,visible,partially lethal - majority die,some die during pupal stage,lethal,gravitaxis defective,conditional,heat stress response defective,neuroanatomy defective" "wing,wing margin,adult brain,conditional,eye" FBgn0029833 MCTS1 Malignant T cell amplified sequence 1 http://flybase.net/reports/FBgn0029833.html "FBgn0066845, FBgn0066846" protein_coding_gene 0003723=RNA binding "0045948=positive regulation of translational initiation, 0002188=translation reinitiation" "MCT-1, multiple copies in T-cell lymphoma-1, anon-WO03040301.150, anon-WO03040301.151, CG5941" "IPR004521=Uncharacterised domain CHP00451, IPR002478=PUA domain, IPR016437=Translation-associated RNA-binding, predicted, IPR015947=PUA-like domain" CG5941 16-Dec-15 2015_12 ENSDARG00000025972(mcts1) YER007C-A(TMA20) WBGene00015703(C11D2.7) ENSXETG00000004472(mcts1) "ENSMUSG00000000355(Mcts1),ENSMUSG00000042814(Mcts2)" ENSG00000101898 FBgn0001695 l(1)ESHS16 lethal (1) ESHS16 http://flybase.net/reports/FBgn0001695.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040009 CG17490 http://flybase.net/reports/FBgn0040009.html FBan0017490 protein_coding_gene CG17490 16-Dec-15 2015_12 FBgn0026605 Act88F::Hsap\ACTC1 Act88F::Hsap\ACTC http://flybase.net/reports/FBgn0026605.html engineered_fusion_gene Act88F::Hsap\ACTC 16-Dec-15 2015_12 FBgn0060698 l(3)S072114 lethal (3) S072114 http://flybase.net/reports/FBgn0060698.html gene 0721/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0004693 Snb Snowblind http://flybase.net/reports/FBgn0004693.html gene Snow blind 16-Dec-15 2015_12 FBgn0004166 l(2)52AD lethal (2) 52AD http://flybase.net/reports/FBgn0004166.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266791 CR45256 http://flybase.net/reports/FBgn0266791.html non_protein_coding_gene CR45256 16-Dec-15 2015_12 FBgn0060729 l(3)S067501 lethal (3) S067501 http://flybase.net/reports/FBgn0060729.html gene 0675/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0020777 tak takahe http://flybase.net/reports/FBgn0020777.html gene "0048598=embryonic morphogenesis, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces" "beerbelly, bee" 16-Dec-15 2015_12 "visible,somatic clone,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,somatic clone,embryonic/first instar larval cuticle,dorsal,presumptive embryonic/larval digestive system,myoblast,dorsal closure embryo" FBgn0033727 Or49a Odorant receptor 49a http://flybase.net/reports/FBgn0033727.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0042048=olfactory behavior, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR10, OR49a, CG13158, 49a, 49A.1" "IPR004117=Olfactory receptor, Drosophila" CG13158 16-Dec-15 2015_12 "viable,fertile,smell perception defective,visible" trichogen cell FBgn0082937 snoRNA:Me28S-C2645b http://flybase.net/reports/FBgn0082937.html snoRNA_gene "snoRNA:Me28S-Cm2645b, CR34588, Me28S-Cm2645b, DmSnR64b" CR34588 16-Dec-15 2015_12 FBgn0070045 3R-168-17 3R-168-17 http://flybase.net/reports/FBgn0070045.html gene 0007379=segment specification 16-Dec-15 2015_12 "embryonic segment,germline clone,maternal effect,embryonic/first instar larval cuticle" FBgn0004485 l(1)air12 lethal aberrant immune response 12 http://flybase.net/reports/FBgn0004485.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0031547 Sr-CIV "Scavenger receptor class C, type IV" http://flybase.net/reports/FBgn0031547.html protein_coding_gene "0030247=polysaccharide binding, 0005044=scavenger receptor activity" "0006952=defense response, 0006955=immune response" "0016020=membrane, 0005887=integral component of plasma membrane" "CG3212, CT10789, SR-CIV" "IPR001212=Somatomedin B domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR000998=MAM domain, IPR000436=Sushi/SCR/CCP domain" CG3212 16-Dec-15 2015_12 "ENSDARG00000068475,ENSDARG00000024017" "ENSXETG00000020534(MEP1B),ENSXETG00000016251(Q5FVY5_XENTR)" "ENSMUSG00000026399(Cd55),ENSMUSG00000026401(Daf2)" viable FBgn0264939 CR44108 http://flybase.net/reports/FBgn0264939.html non_protein_coding_gene CR44108 16-Dec-15 2015_12 FBgn0065825 l(2)SH0360 lethal (2) SH0360 http://flybase.net/reports/FBgn0065825.html gene l(2)SH2 0360 16-Dec-15 2015_12 "lethal,recessive" FBgn0265201 CG44261 http://flybase.net/reports/FBgn0265201.html protein_coding_gene CG44261 16-Dec-15 2015_12 FBgn0260357 GSd420 http://flybase.net/reports/FBgn0260357.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0266624 CR45131 http://flybase.net/reports/FBgn0266624.html non_protein_coding_gene CR45131 16-Dec-15 2015_12 FBgn0004015 with with trident http://flybase.net/reports/FBgn0004015.html gene 16-Dec-15 2015_12 scutum FBgn0026203 mkf mokkaife http://flybase.net/reports/FBgn0026203.html gene 0007268=synaptic transmission 16-Dec-15 2015_12 FBgn0029035 l(2)Q1 lethal (2) Q1 http://flybase.net/reports/FBgn0029035.html gene Q1 16-Dec-15 2015_12 "lethal,recessive" FBgn0039343 CG5111 http://flybase.net/reports/FBgn0039343.html protein_coding_gene "IPR029071=Ubiquitin-related domain, IPR015940=Ubiquitin-associated domain, IPR009060=UBA-like" CG5111 16-Dec-15 2015_12 ENSDARG00000061417(LOC100330264) ENSMUSG00000028954(Nub1) ENSG00000013374(NUB1) viable FBgn0016025 l(3)89Bn lethal (3) 89Bn http://flybase.net/reports/FBgn0016025.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027959 l(3)S147506 lethal (3) S147506 http://flybase.net/reports/FBgn0027959.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023416 Ac3 Ac3 http://flybase.net/reports/FBgn0023416.html protein_coding_gene 0004016=adenylate cyclase activity "0006171=cAMP biosynthetic process, 0045475=locomotor rhythm, 0035556=intracellular signal transduction" "0016021=integral component of membrane, 0005886=plasma membrane" "AC 3, adenylate cyclase 3, AC3, DAC3, DAC39E, CG1506" "IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR030672=Adenylate cyclase" CG1506 16-Dec-15 2015_12 ENSDARG00000017437(adcy3) ENSXETG00000021179(ADCY3) ENSMUSG00000020654(Adcy3) ENSG00000138031(ADCY3) " larval stage , adult stage , embryonic stage " " adult stage , embryonic stage | 10-18 hr " " optic lobe neuron

, antennal lobe

, adult head

, neuropil

, subesophageal ganglion

, adult brain

, antenna

" "locomotor rhythm defective,viable,fertile" FBgn0034483 CG16894 http://flybase.net/reports/FBgn0034483.html protein_coding_gene "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG16894 16-Dec-15 2015_12 ENSDARG00000026862(aktip) WBGene00006714(ubc-19) ENSXETG00000008091(fts) ENSMUSG00000031667(Aktip) ENSG00000166971(AKTIP) viable FBgn0266362 CR45010 http://flybase.net/reports/FBgn0266362.html non_protein_coding_gene CR45010 16-Dec-15 2015_12 FBgn0262405 mir-998 mir-998 stem loop http://flybase.net/reports/FBgn0262405.html "FBgn0259156, FBgn0262241" miRNA_gene "0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0060548=negative regulation of cell death" "dme-miR-998-3p, CR42948, 998, miR-998" CR42948 16-Dec-15 2015_12 viable FBgn0052487 CG32487 http://flybase.net/reports/FBgn0052487.html FBgn0035386 protein_coding_gene "0004035=alkaline phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0016791=phosphatase activity" 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" "Phos32487, CG2077, 24656330" "IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR023215=Nitrophenylphosphatase-like domain, IPR006349=2-phosphoglycolate phosphatase, eukaryotic, IPR023214=HAD-like domain" CG32487 16-Dec-15 2015_12 YDL236W(PHO13) "WBGene00016892(C53A3.2),WBGene00019604(K09H11.7),WBGene00018424(F44E7.2)" "ENSMUSG00000043445(Pgp),ENSMUSG00000068221(Pdxp)" viable FBgn0058128 CG40128 http://flybase.net/reports/FBgn0058128.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036889 CG14100 http://flybase.net/reports/FBgn0036889.html protein_coding_gene "0008173=RNA methyltransferase activity, 0003723=RNA binding" 0006396=RNA processing 0005875=microtubule associated complex "IPR029064=50S ribosomal protein L30e-like, IPR029028=Alpha/beta knot methyltransferases, IPR029026=tRNA (guanine-N1-)-methyltransferase, N-terminal, IPR001537=tRNA/rRNA methyltransferase, SpoU type, IPR013123=RNA 2-O ribose methyltransferase, substrate binding" CG14100 16-Dec-15 2015_12 "ENSDARG00000016543(rnmtl1a),ENSDARG00000069082(rnmtl1b)" ENSXETG00000022451(RNMTL1) ENSMUSG00000038046(Rnmtl1) ENSG00000171861(RNMTL1) viable FBgn0025693 ZnT41F Zinc transporter 41F http://flybase.net/reports/FBgn0025693.html FBgn0033040 protein_coding_gene 0005385=zinc ion transmembrane transporter activity "0006812=cation transport, 0055085=transmembrane transport" "0016021=integral component of membrane, 0005622=intracellular" "dZnT41F, CK02137, CG11163, BEST:CK02137, cg11163" "IPR002524=Cation efflux protein, IPR027469=Cation efflux protein transmembrane domain" CG11163 16-Dec-15 2015_12 ENSXETG00000022040(SLC30A4) "ENSMUSG00000028836(Slc30a2),ENSMUSG00000029151(Slc30a3)" "viable,fertile" FBgn0265835 CG44624 http://flybase.net/reports/FBgn0265835.html protein_coding_gene CG44624 16-Dec-15 2015_12 FBgn0050393 CG30393 http://flybase.net/reports/FBgn0050393.html FBgn0034607 protein_coding_gene CG15662 CG30393 16-Dec-15 2015_12 "viable,fertile" FBgn0000972 fs(2)HO3 female sterile (2) HO3 http://flybase.net/reports/FBgn0000972.html gene "fs(2)3A, fs(1)3A" 16-Dec-15 2015_12 FBgn0069451 E(br)160 E(br)160 http://flybase.net/reports/FBgn0069451.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261955 kdn knockdown http://flybase.net/reports/FBgn0261955.html "FBgn0001298, FBgn0026708, FBgn0028354, FBgn0029078, FBgn0029869, FBgn0045802, FBgn0086133, FBgn0023394" protein_coding_gene 0004108=citrate (Si)-synthase activity "0044262=cellular carbohydrate metabolic process, 0005975=carbohydrate metabolic process, 0006099=tricarboxylic acid cycle" "0005739=mitochondrion, 0005875=microtubule associated complex, 0005759=mitochondrial matrix" "citrate synthase, BEST:GM01832, CS, l(1)G0159, Citrate synthase, l(1)G0030, l (1) G0030, l(1)G0033, lethal (1) G0030, CG3861, CG 3861, Csyn" "IPR002020=Citrate synthase, IPR010109=Citrate synthase, eukaryotic-type, IPR019810=Citrate synthase active site, IPR016142=Citrate synthase-like, large alpha subdomain" CG3861 16-Dec-15 2015_12 ENSDARG00000070395(cs) "YNR001C(CIT1),YCR005C(CIT2)" WBGene00000833(cts-1) ENSXETG00000009506(cs) "ENSMUSG00000005683(Cs),ENSMUSG00000046934(Csl)" ENSG00000062485(CS) FBgn0015075 Ddx1 Dead-box-1 http://flybase.net/reports/FBgn0015075.html FBgn0013790 protein_coding_gene "0033677=DNA/RNA helicase activity, 0004386=helicase activity, 0003682=chromatin binding, 0003712=transcription cofactor activity, 0004518=nuclease activity, 0005524=ATP binding, 0008143=poly(A) binding, 0008026=ATP-dependent helicase activity" "0032508=DNA duplex unwinding, 0000245=spliceosomal complex assembly, 0042254=ribosome biogenesis, 0006302=double-strand break repair, 0001700=embryonic development via the syncytial blastoderm, 0006446=regulation of translational initiation" 0005634=nucleus "CG9054, unnamed, DmDDX1, DDX1, DmRH12, Dbp79E, anon-79E" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003877=SPRY domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR011545=DEAD/DEAH box helicase domain, IPR001870=B30.2/SPRY domain, IPR001650=Helicase, C-terminal" CG9054 16-Dec-15 2015_12 ENSDARG00000032117(si:ch211-214k9.2) WBGene00021938(Y55F3BR.1) ENSXETG00000017825(ddx1) ENSMUSG00000037149(Ddx1) ENSG00000079785(DDX1) embryonic stage -- adult stage organism

"viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0062260 Rasta Rasta http://flybase.net/reports/FBgn0062260.html gene 0016055=Wnt signaling pathway 16-Dec-15 2015_12 FBgn0046879 Obp56c Odorant-binding protein 56c http://flybase.net/reports/FBgn0046879.html "FBgn0034469, FBgn0050128" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp56c, OBP56c, CG30128, 56c, CG15129" IPR006170=Pheromone/general odorant binding protein CG30128 16-Dec-15 2015_12 FBgn0030073 CG10962 http://flybase.net/reports/FBgn0030073.html "FBgn0030072, FBgn0047129, FBgn0062683" protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process "EP(X)1565, EP1565, BcDNA:RE29909, CG7090" "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG10962 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0070035 966 966 http://flybase.net/reports/FBgn0070035.html gene 0019094=pole plasm mRNA localization 16-Dec-15 2015_12 FBgn0085203 CG34174 http://flybase.net/reports/FBgn0085203.html protein_coding_gene CG34174 16-Dec-15 2015_12 ENSXETG00000010255(CINP) FBgn0040391 CG2854 http://flybase.net/reports/FBgn0040391.html FBgn0029611 protein_coding_gene EG:BACH48C10.2 "IPR028031=Domain of unknown function DUF4460, IPR027989=Domain of unknown function DUF4461, IPR027986=T-cell activation inhibitor, mitochondrial" CG2854 16-Dec-15 2015_12 WBGene00016438(C35B8.3) ENSXETG00000005361(C3orf23) ENSMUSG00000046603(D9Ertd402e) ENSG00000179152(C3orf23) viable FBgn0028208 l(3)S011028 lethal (3) S011028 http://flybase.net/reports/FBgn0028208.html gene 0110/28 16-Dec-15 2015_12 "lethal,recessive" FBgn0033059 CG7845 http://flybase.net/reports/FBgn0033059.html protein_coding_gene 0046716=muscle cell cellular homeostasis "WDR74, CG745" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG7845 16-Dec-15 2015_12 ENSDARG00000061993(wdr74) WBGene00011538(T06E6.1) ENSXETG00000019440(wdr74) ENSMUSG00000042729(Wdr74) ENSG00000133316(WDR74) "visible,partially lethal - majority die,some die during pupal stage,female sterile" mesothoracic tergum DRSC04894 I -1.628894945 -0.270525551 0.439573142 -0.268996127 -0.2331193 -0.441858193 FBgn0037432 CG10298 http://flybase.net/reports/FBgn0037432.html FBgn0063214 protein_coding_gene BcDNA:GH28351 "IPR008914=Phosphatidylethanolamine-binding protein PEBP, IPR001858=Phosphatidylethanolamine-binding, conserved site" CG10298 16-Dec-15 2015_12 ENSDARG00000042069(pbp) "YLR179C(),YLR178C(TFS1)" ENSXETG00000022375(pebp) "ENSMUSG00000048362(Gm9824),ENSMUSG00000032959(Pebp1),ENSMUSG00000047104(Pbp2)" ENSG00000089220(PEBP1) viable FBgn0060793 l(3)S058507b lethal (3) S058507b http://flybase.net/reports/FBgn0060793.html gene 0585/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0020827 l(2)WO "Wooster, Ohio" http://flybase.net/reports/FBgn0020827.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024264 acd(2)5L3 auditory courtship defective 5L3 http://flybase.net/reports/FBgn0024264.html gene "0031223=auditory behavior, 0008049=male courtship behavior" "5L3, unnamed" 16-Dec-15 2015_12 "viable,auditory perception defective,courtship behavior defective,male,male fertile" FBgn0267644 CR45982 http://flybase.net/reports/FBgn0267644.html non_protein_coding_gene CR45982 16-Dec-15 2015_12 FBgn0022735 hypnos-3 "hypoxia, anoxia, sensitive 3" http://flybase.net/reports/FBgn0022735.html gene 0001666=response to hypoxia 16-Dec-15 2015_12 "neurophysiology defective,dominant,behavior defective,recessive" adult central nervous system FBgn0003370 sge shifted genitals http://flybase.net/reports/FBgn0003370.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective,male sterile,viable,male,reduced" "genitalia,anal plate,wing,eye" FBgn0030787 CG9609 http://flybase.net/reports/FBgn0030787.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG9609 16-Dec-15 2015_12 "ENSDARG00000030267(gtf3aa),ENSDARG00000071583(zgc:162349),ENSDARG00000040022(si:dkey-208k4.2)" ENSG00000122034(GTF3A) viable DRSC20199 K 0.264848805 -0.478915076 0.331729031 1.101772272 1.874208159 -1.005765552 FBgn0003585 Su(var) Suppressor of variegation http://flybase.net/reports/FBgn0003585.html gene "Su_var, Su-V, Suppressor of variegation" 16-Dec-15 2015_12 "viable,male fertile,female fertile,reduced,suppressor of variegation,enhancer of variegation" FBgn0264825 CR44033 http://flybase.net/reports/FBgn0264825.html non_protein_coding_gene lincRNA.825 CR44033 16-Dec-15 2015_12 FBgn0030386 CG2574 http://flybase.net/reports/FBgn0030386.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0016567=protein ubiquitination bs21b01.y1 "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG2574 16-Dec-15 2015_12 viable FBgn0039070 CG17083 http://flybase.net/reports/FBgn0039070.html protein_coding_gene 0036158=outer dynein arm assembly 0036157=outer dynein arm IPR029652=ODA1/DCC2 family CG17083 16-Dec-15 2015_12 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0267232 CR45672 http://flybase.net/reports/FBgn0267232.html non_protein_coding_gene CR45672 16-Dec-15 2015_12 FBgn0028170 l(3)S027403b lethal (3) S027403b http://flybase.net/reports/FBgn0028170.html gene "0274/03, l(3)S027403" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0267430 Pzl Piezo-like http://flybase.net/reports/FBgn0267430.html "FBgn0261280, FBan0040249, FBgn0058249, FBan0040188, FBgn0058188, FBan0041369, FBgn0085634, FBan0041238, FBgn0085566, FBgn0261281, FBgn0058328, FBan0041056, FBgn0085781, FBgn0058232" protein_coding_gene 0008381=mechanically-gated ion channel activity 0016021=integral component of membrane "CG40249, CG42618, CG42617, CG40328, CG41369, CG40188, CG45783, CG41238, CG41056, CR41056, CG40232" "IPR027272=Piezo family, IPR031334=Piezo non-specific cation channel, R-Ras-binding domain" CG45783 16-Dec-15 2015_12 ENSXETG00000004054() ENSMUSG00000073549 ENSG00000175388 FBgn0265909 CR44698 http://flybase.net/reports/FBgn0265909.html non_protein_coding_gene lincRNA.39 CR44698 16-Dec-15 2015_12 FBgn0283427 FASN1 Fatty acid synthase 1 http://flybase.net/reports/FBgn0283427.html "FBgn0027571, FBgn0027682, FBgn0027719, FBgn0044793, FBgn0022805" protein_coding_gene "0004316=3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity, 0004312=fatty acid synthase activity, 0004320=oleoyl-[acyl-carrier-protein] hydrolase activity, 0016296=palmitoyl-[acyl-carrier-protein] hydrolase activity, 0004313=[acyl-carrier-protein] S-acetyltransferase activity, 0004315=3-oxoacyl-[acyl-carrier-protein] synthase activity, 0004319=enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity, 0004317=3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity, 0016295=myristoyl-[acyl-carrier-protein] hydrolase activity, 0004314=[acyl-carrier-protein] S-malonyltransferase activity, 0008270=zinc ion binding" "0009744=response to sucrose, 0019432=triglyceride biosynthetic process, 0005977=glycogen metabolic process, 0071329=cellular response to sucrose stimulus" 0005811=lipid particle "DM_7295848, anon-WO0138581.1, Fas, dFAS, Fatty Acid Synthase, Fatty acid synthase, FASN[CG3523], BcDNA:gh07626, Fatty acid synthetase, BcDNA:GH07626, CG3523, anon-EST:Posey43, FAS[CG3523], fas, fatty acid synthase, anon-EST:Posey235, FASN, FAS" "IPR011032=GroES-like, IPR016039=Thiolase-like, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase, IPR001031=Thioesterase, IPR013968=Polyketide synthase, ketoreductase domain, IPR009081=Acyl carrier protein-like, IPR013149=Alcohol dehydrogenase, C-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR014043=Acyl transferase, IPR016040=NAD(P)-binding domain, IPR020843=Polyketide synthase, enoylreductase domain, IPR018201=Beta-ketoacyl synthase, active site, IPR020807=Polyketide synthase, dehydratase domain, IPR023102=Fatty acid synthase, domain 2, IPR014031=Beta-ketoacyl synthase, C-terminal, IPR001227=Acyl transferase domain, IPR016036=Malonyl-CoA ACP transacylase, ACP-binding, IPR014030=Beta-ketoacyl synthase, N-terminal" CG3523 16-Dec-15 2015_12 "ENSDARG00000068882,ENSDARG00000068878(si:dkey-61p9.11),ENSDARG00000071470" WBGene00009342(fasn-1) ENSXETG00000019666(FASN) ENSMUSG00000025153(Fasn) ENSG00000169710(FASN) "visible,viable,increased cell death,lethal,conditional" "wing,embryonic/larval hemolymph | third instar larval stage" DRSC00268 IE -0.278339281 2.095959839 1.070689429 -3.689618051 0.201414598 -0.961430827 FBgn0266615 CG45122 http://flybase.net/reports/FBgn0266615.html protein_coding_gene CG45122 16-Dec-15 2015_12 FBgn0001328 ks-2 male fertility factor ks2 http://flybase.net/reports/FBgn0001328.html gene "ks2, Sms2" 16-Dec-15 2015_12 male sterile testis FBgn0011633 l(2)T57h6 lethal (2) T57h6 http://flybase.net/reports/FBgn0011633.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0002936 ninaA neither inactivation nor afterpotential A http://flybase.net/reports/FBgn0002936.html protein_coding_gene "0016018=cyclosporin A binding, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0016063=rhodopsin biosynthetic process, 0000413=protein peptidyl-prolyl isomerization, 0007603=phototransduction, visible light, 0006458='de novo' protein folding, 0007602=phototransduction, 0006810=transport, 0006491=N-glycan processing, 0070059=intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, 0006517=protein deglycosylation, 0006457=protein folding" "0031965=nuclear membrane, 0016021=integral component of membrane, 0005788=endoplasmic reticulum lumen, 0005887=integral component of plasma membrane, 0016023=cytoplasmic membrane-bounded vesicle, 0016028=rhabdomere" "CG3966, either inactivation nor afterpotential A, ninA, NinaA, NINAA, Neither inactivation nor after potential" "IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR029000=Cyclophilin-like domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase" CG3966 16-Dec-15 2015_12 " pupal stage | late , adult stage " adult head

"visible,recessive,neurophysiology defective,wild-type,heat sensitive,cold sensitive,increased cell death" "photoreceptor cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,retina,conditional,photoreceptor cell & endoplasmic reticulum,ommatidium" FBgn0053743 snmRNA:430:CR33743 snmRNA:430:CR33743 http://flybase.net/reports/FBgn0053743.html non_protein_coding_gene CR33743 CR33743 16-Dec-15 2015_12 FBgn0022286 l(2)254 lethal (2) 254 http://flybase.net/reports/FBgn0022286.html gene 254 16-Dec-15 2015_12 "lethal,recessive" FBgn0032956 Cul2 Cullin 2 http://flybase.net/reports/FBgn0032956.html FBgn0010507 protein_coding_gene 0031625=ubiquitin protein ligase binding "0048140=male germ-line cyst encapsulation, 0007281=germ cell development, 0016567=protein ubiquitination, 0022008=neurogenesis, 0007295=growth of a germarium-derived egg chamber, 0008582=regulation of synaptic growth at neuromuscular junction, 0006511=ubiquitin-dependent protein catabolic process" "0000152=nuclear ubiquitin ligase complex, 0031462=Cul2-RING ubiquitin ligase complex" "Cullin-2, CG1512, Cullin2, CUL2, cul-2, Cul2, DMcul-2, Cullin 2, l(2)02074, dCul2, cul2, Cul-2" "IPR016157=Cullin, conserved site, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019559=Cullin protein, neddylation domain, IPR016158=Cullin homology, IPR001373=Cullin, N-terminal, IPR016159=Cullin repeat-like-containing domain" CG1512 16-Dec-15 2015_12 ENSDARG00000013965(cul2) WBGene00000837(cul-2) ENSXETG00000008815(CUL2) ENSMUSG00000024231(Cul2) ENSG00000108094(CUL2) "fertile,lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable,female sterile,recessive" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,NMJ bouton,supernumerary,egg chamber,interfollicle cell,nurse cell,oocyte,germarium,terminal filament" FBgn0250838 CG30415 http://flybase.net/reports/FBgn0250838.html "FBgn0050415, FBgn0034857, FBgn0066919" protein_coding_gene "anon-SAGE:Wang-079, CG3487" CG30415 16-Dec-15 2015_12 DRSC04003 K -1.20318073 -1.200392626 -0.730692694 -0.405500764 1.838270475 0.463103706 FBgn0021794 l(2)k17019b lethal (2) k17019b http://flybase.net/reports/FBgn0021794.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058385 CG40385 http://flybase.net/reports/FBgn0058385.html FBan0040385 protein_coding_gene 16-Dec-15 2015_12 FBgn0014386 slk schluckless http://flybase.net/reports/FBgn0014386.html gene 16-Dec-15 2015_12 FBgn0038590 CG12320 http://flybase.net/reports/FBgn0038590.html protein_coding_gene "0030532=small nuclear ribonucleoprotein complex, 0005737=cytoplasm" Aar2 "IPR007946=A1 cistron-splicing factor, AAR2" CG12320 16-Dec-15 2015_12 ENSDARG00000018658(zgc:92018) WBGene00008639(F10B5.2) ENSXETG00000012109(C20orf4) ENSMUSG00000027628(0610011L14Rik) ENSG00000131043(C20orf4) "viable,visible" trichogen cell FBgn0019758 l(1)75B2 lethal (1) 75B2 http://flybase.net/reports/FBgn0019758.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051872 CG31872 http://flybase.net/reports/FBgn0051872.html "FBgn0032272, FBgn0032273" protein_coding_gene 0004806=triglyceride lipase activity "0032504=multicellular organism reproduction, 0006629=lipid metabolic process" 0005615=extracellular space "CG17093, CG17101" "IPR006693=Partial AB-hydrolase lipase domain, IPR029058=Alpha/Beta hydrolase fold" CG31872 16-Dec-15 2015_12 viable FBgn0260272 GSd422 http://flybase.net/reports/FBgn0260272.html gene 16-Dec-15 2015_12 lethal FBgn0024483 Cir Cir http://flybase.net/reports/FBgn0024483.html gene 0003714=transcription corepressor activity 0007219=Notch signaling pathway DCIR 16-Dec-15 2015_12 FBgn0030744 CG9992 http://flybase.net/reports/FBgn0030744.html protein_coding_gene CG9992 16-Dec-15 2015_12 FBgn0063889 anon-10Eb anon-10Eb http://flybase.net/reports/FBgn0063889.html gene unnamed 16-Dec-15 2015_12 FBgn0028188 l(3)S023635 lethal (3) S023635 http://flybase.net/reports/FBgn0028188.html gene "0236/35, 0553/10, 0726/03" 16-Dec-15 2015_12 "lethal,recessive" FBgn0283494 Adk2 Adenylate kinase 2 http://flybase.net/reports/FBgn0283494.html "FBgn0020537, FBgn0020538, FBgn0021824, FBgn0022708, FBgn0024906, FBgn0064780" protein_coding_gene "0005524=ATP binding, 0004017=adenylate kinase activity" "0022008=neurogenesis, 0006172=ADP biosynthetic process" "0005758=mitochondrial intermembrane space, 0005739=mitochondrion, 0005811=lipid particle" "l(2)k16120, ADENYLATE KINASE-2, l(2)04201, BcDNA:SD09634, CG3140, ADK-2, Adenylate kinase-2, Adk2-60B, l(2)k04201, anon-Dak2, l(2)k04209, l(2)04209, Adk2-44B, Dak2" "IPR006259=Adenylate kinase subfamily, IPR000850=Adenylate kinase/UMP-CMP kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR028587=Adenylate kinase 2, IPR007862=Adenylate kinase, active site lid domain" CG3140 16-Dec-15 2015_12 ENSDARG00000005926(ak2) YDR226W(ADK1) WBGene00002879(let-754) ENSXETG00000027867(ak2) ENSMUSG00000028792(Ak2) ENSG00000004455(AK2) FBgn0082677 E(ftz)5303 E(ftz)5303 http://flybase.net/reports/FBgn0082677.html gene 5303 16-Dec-15 2015_12 FBgn0025632 CG4313 http://flybase.net/reports/FBgn0025632.html protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway "0005886=plasma membrane, 0016021=integral component of membrane" EG:22E5.10 "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG4313 16-Dec-15 2015_12 "ENSDARG00000069225,ENSDARG00000069221,ENSDARG00000055852(LOC565718),ENSDARG00000037545(mtnr1aa),ENSDARG00000035609(mtnr1c),ENSDARG00000012057" ENSXETG00000021274(GPR84) ENSMUSG00000063234(Gpr84) ENSG00000139572(GPR84) FBgn0260260 GSd331 http://flybase.net/reports/FBgn0260260.html gene 16-Dec-15 2015_12 lethal FBgn0038140 PK2-R1 Pyrokinin 2 receptor 1 http://flybase.net/reports/FBgn0038140.html "FBgn0046556, FBgn0046557" protein_coding_gene "0004930=G-protein coupled receptor activity, 0036401=pyrokinin receptor activity, 0008188=neuropeptide receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "anon-WO0170980.191, Pyrokinin 2 receptor, Dm CG8784, CG8784, anon-WO0170980.190" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG8784 16-Dec-15 2015_12 ENSDARG00000042939(gpr39) WBGene00016265(nmur-4) "viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" DRSC16447 K 0.515563735 -0.403844144 0.285066669 -0.806803689 3.259555012 2.565470539 FBgn0065642 l(2)SH0757 lethal (2) SH0757 http://flybase.net/reports/FBgn0065642.html gene l(2)SH2 0757 16-Dec-15 2015_12 "lethal,recessive" FBgn0259336 EP-65 http://flybase.net/reports/FBgn0259336.html gene 16-Dec-15 2015_12 visible wing vein FBgn0264710 CR43979 http://flybase.net/reports/FBgn0264710.html non_protein_coding_gene CR43979 16-Dec-15 2015_12 FBgn0053258 CG33258 http://flybase.net/reports/FBgn0053258.html FBgn0082905 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "CR33258, unnamed, BP1001" IPR002557=Chitin binding domain CG33258 16-Dec-15 2015_12 FBgn0014059 Su(tor)2-56 Su(tor)2-56 http://flybase.net/reports/FBgn0014059.html gene 16-Dec-15 2015_12 FBgn0044493 DTD45.8 DTD45.8 http://flybase.net/reports/FBgn0044493.html gene 16-Dec-15 2015_12 viable FBgn0031681 pgant5 polypeptide GalNAc transferase 5 http://flybase.net/reports/FBgn0031681.html "FBgn0051651, FBgn0082589" protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process "0012505=endomembrane system, 0005795=Golgi stack" "l(2)e02157, CG31651, CG9152, lethal (2) e02157, PGANT5" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain, IPR001173=Glycosyltransferase 2-like" CG31651 16-Dec-15 2015_12 ENSDARG00000061335(LOC559073) WBGene00001628(gly-3) "ENSXETG00000014012(galnt1),ENSXETG00000021716(galnt13)" "ENSMUSG00000000420(Galnt1),ENSMUSG00000060988(Galnt13)" "ENSG00000141429(GALNT1),ENSG00000144278(GALNT13)" "viable,lethal,recessive,partially lethal - majority die" "embryonic/larval gut,embryonic/larval cuprophilic cell" FBgn0266935 CR45386 http://flybase.net/reports/FBgn0266935.html non_protein_coding_gene lincRNA.619 CR45386 16-Dec-15 2015_12 FBgn0015347 anon-87Ae anon-87Ae http://flybase.net/reports/FBgn0015347.html gene 87A7-9/6 16-Dec-15 2015_12 FBgn0036588 CG13068 http://flybase.net/reports/FBgn0036588.html protein_coding_gene CG13068 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" FBgn0002472 l(3)SG27 lethal (3) SG27 http://flybase.net/reports/FBgn0002472.html FBgn0004716 gene "l(3)B17, l(3)ds17" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0266947 CR45398 http://flybase.net/reports/FBgn0266947.html non_protein_coding_gene CR45398 16-Dec-15 2015_12 FBgn0030481 CG1662 http://flybase.net/reports/FBgn0030481.html protein_coding_gene 0005779=integral component of peroxisomal membrane IPR007248=Mpv17/PMP22 CG1662 16-Dec-15 2015_12 ENSDARG00000056367(mpv17l2) YOR292C() ENSXETG00000018317(BC075397.1) "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0040760 CG13181 http://flybase.net/reports/FBgn0040760.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036318 Wbp2 Wbp2 ortholog http://flybase.net/reports/FBgn0036318.html protein_coding_gene "0045893=positive regulation of transcription, DNA-templated, 0035329=hippo signaling, 0045572=positive regulation of imaginal disc growth" "0005737=cytoplasm, 0005634=nucleus" "wbp2, CG11009" "IPR004182=GRAM domain, IPR018826=WW-domain-binding protein" CG11009 16-Dec-15 2015_12 "ENSDARG00000056605(zgc:109985),ENSDARG00000044852(wbp2)" WBGene00015955(C18B2.4) "ENSXETG00000012581(WBP2),ENSXETG00000006890(WBP2NL)" ENSMUSG00000034341(Wbp2) ENSG00000132471(WBP2) "size defective,viable" wing margin FBgn0002060 l(2)40Fe lethal (2) 40Fe http://flybase.net/reports/FBgn0002060.html gene "GroupVII, l(2Lh)Fe, 40Fe, l(2L)D" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" wing FBgn0000245 c curved http://flybase.net/reports/FBgn0000245.html gene C 16-Dec-15 2015_12 "visible,recessive,dominant" wing FBgn0036438 CG13477 http://flybase.net/reports/FBgn0036438.html protein_coding_gene CG13477 16-Dec-15 2015_12 viable FBgn0039680 Cap-D2 CAP-D2 condensin subunit http://flybase.net/reports/FBgn0039680.html protein_coding_gene 0003682=chromatin binding "0007076=mitotic chromosome condensation, 0000070=mitotic sister chromatid segregation, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization" "0005634=nucleus, 0000796=condensin complex, 0000779=condensed chromosome, centromeric region, 0000785=chromatin, 0005737=cytoplasm, 0000793=condensed chromosome" "Cap-D2, DmCAP-D2, CapD2, CAP-D2, dCap-D2, CG1911" "IPR016024=Armadillo-type fold, IPR007673=Condensin subunit 1, IPR024324=Condensin complex, subunit 1, N-terminal, IPR026971=Condensin subunit 1/Condensin-2 complex subunit D3, IPR011989=Armadillo-like helical" CG1911 16-Dec-15 2015_12 YLR272C(YCS4) WBGene00001087(dpy-28) ENSXETG00000011528(gapdh) ENSMUSG00000038252(Ncapd2) ENSG00000010292(NCAPD2) "partially lethal - majority die,some die during pupal stage" FBgn0051835 CG31835 http://flybase.net/reports/FBgn0051835.html FBgn0028930 protein_coding_gene 0008270=zinc ion binding BG:DS00810.1 "IPR008598=Drought induced 19 protein type, zinc-binding domain, IPR015880=Zinc finger, C2H2-like, IPR000433=Zinc finger, ZZ-type" CG31835 16-Dec-15 2015_12 ENSXETG00000009533(KCMF1) ENSMUSG00000055239(Kcmf1) viable FBgn0038609 Nup43 Nucleoporin 43kD http://flybase.net/reports/FBgn0038609.html protein_coding_gene 0007067=mitotic nuclear division 0031080=nuclear pore outer ring "CG7671, nup43, nucleoporin 43, Nucleoporin 43" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG7671 16-Dec-15 2015_12 ENSDARG00000043884(nup43) WBGene00007493(C09G9.2) ENSXETG00000016373(nup43) ENSMUSG00000040034(Nup43) ENSG00000120253(NUP43) viable FBgn0065632 l(2)SH0778 lethal (2) SH0778 http://flybase.net/reports/FBgn0065632.html gene l(2)SH2 0778 16-Dec-15 2015_12 "lethal,recessive" FBgn0267258 CR45694 http://flybase.net/reports/FBgn0267258.html non_protein_coding_gene CR45694 16-Dec-15 2015_12 FBgn0263332 CR43413 http://flybase.net/reports/FBgn0263332.html non_protein_coding_gene CR43413 16-Dec-15 2015_12 FBgn0263099 ths::pyr http://flybase.net/reports/FBgn0263099.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0262895 CR43250 http://flybase.net/reports/FBgn0262895.html non_protein_coding_gene "CG43250, lincRNA.587" CR43250 16-Dec-15 2015_12 FBgn0001213 hpa hyperantenna http://flybase.net/reports/FBgn0001213.html gene 16-Dec-15 2015_12 "visible,viable,sterile,female sterile,male sterile" "antenna,adult head,eye,wing,macrochaeta" FBgn0070008 BG01428 BG01428 http://flybase.net/reports/FBgn0070008.html gene 16-Dec-15 2015_12 stress response defective FBgn0267194 CR45634 http://flybase.net/reports/FBgn0267194.html non_protein_coding_gene CR45634 16-Dec-15 2015_12 FBgn0021773 ms(3)P115 ms(3)P115 http://flybase.net/reports/FBgn0021773.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0029155 Men-b Malic enzyme b http://flybase.net/reports/FBgn0029155.html "FBgn0027671, FBgn0039493" protein_coding_gene "0004471=malate dehydrogenase (decarboxylating) (NAD+) activity, 0004473=malate dehydrogenase (decarboxylating) (NADP+) activity, 0051287=NAD binding" "0006108=malate metabolic process, 0006090=pyruvate metabolic process, 0055114=oxidation-reduction process" 0005739=mitochondrion "Malic DH, MDH, anon-EST:Posey79, Mdh, CG5889" "IPR015884=Malic enzyme, conserved site, IPR001891=Malic oxidoreductase, IPR012302=Malic enzyme, NAD-binding, IPR012301=Malic enzyme, N-terminal domain, IPR016040=NAD(P)-binding domain" CG5889 16-Dec-15 2015_12 "ENSDARG00000002305(me3),ENSDARG00000068987,ENSDARG00000015453(me2),ENSDARG00000053215(LOC100334383)" YKL029C(MAE1) WBGene00012983(men-1) "ENSXETG00000022647(ME1),ENSXETG00000010436(ME3),ENSXETG00000022388(Q5EC53_XENTR)" ENSMUSG00000030621(Me3) ENSG00000151376(ME3) "viable,fertile" FBgn0038428 CG14894 http://flybase.net/reports/FBgn0038428.html protein_coding_gene "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1" CG14894 16-Dec-15 2015_12 ENSDARG00000044567(ttc1) WBGene00016390(C34B2.5) ENSXETG00000005715(TTC1) ENSMUSG00000041278(Ttc1) ENSG00000113312(TTC1) FBgn0000879 fs(1)M77 female sterile (1) M77 http://flybase.net/reports/FBgn0000879.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0032301 CG18561 http://flybase.net/reports/FBgn0032301.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC02675 IEK -2.026884283 -5.031124483 -1.298633208 -3.993139699 -2.628843078 -0.582459373 FBgn0053111 CG33111 http://flybase.net/reports/FBgn0053111.html "FBgn0039121, FBgn0040594, FBgn0040595" protein_coding_gene "CG11945, CG10193, CG11957" CG33111 16-Dec-15 2015_12 FBgn0052760 CG32760 http://flybase.net/reports/FBgn0052760.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039790 CG2246 http://flybase.net/reports/FBgn0039790.html protein_coding_gene "0000287=magnesium ion binding, 0004749=ribose phosphate diphosphokinase activity" 0009165=nucleotide biosynthetic process "IPR005946=Ribose-phosphate diphosphokinase, IPR029099=Ribose-phosphate pyrophosphokinase, N-terminal domain, IPR029057=Phosphoribosyltransferase-like" CG2246 16-Dec-15 2015_12 ENSDARG00000019326(prpsap2) WBGene00012258(W04G3.5) ENSXETG00000019542(prpsap1) "ENSMUSG00000020528(Prpsap2),ENSMUSG00000015869(Prpsap1)" "ENSG00000141127(PRPSAP2),ENSG00000161542(PRPSAP1)" "viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0041127 l(2)45Aj lethal (2) 45Aj http://flybase.net/reports/FBgn0041127.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive" FBgn0030447 CG2200 http://flybase.net/reports/FBgn0030447.html protein_coding_gene "0016805=dipeptidase activity, 0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0005737=cytoplasm "IPR005320=Peptidase S51, IPR029062=Class I glutamine amidotransferase-like" CG2200 16-Dec-15 2015_12 ENSDARG00000070057(si:dkey-69o16.5) ENSXETG00000001084() viable FBgn0062706 EP1062 EP1062 http://flybase.net/reports/FBgn0062706.html gene EP(2)1062 16-Dec-15 2015_12 FBgn0013475 l(1)14P11 lethal (1) 14P11 http://flybase.net/reports/FBgn0013475.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0035011 CG13589 http://flybase.net/reports/FBgn0035011.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG13589 16-Dec-15 2015_12 viable FBgn0069146 mcl(3)Z3946 mcl(3)Z3946 http://flybase.net/reports/FBgn0069146.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0017398 ftz::Sxl ftz::Sxl http://flybase.net/reports/FBgn0017398.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0085197 CG34168 http://flybase.net/reports/FBgn0085197.html protein_coding_gene CG4959 CG34168 16-Dec-15 2015_12 "viable,fertile" FBgn0050254 tRNA:CR30254 transfer RNA:CR30254 http://flybase.net/reports/FBgn0050254.html FBgn0060072 tRNA_gene 0033447=AGA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna82-ArgTCT, AE002787.trna23-ArgTCT, CR30254, tRNA:R:TCT:AE002787" CR30254 16-Dec-15 2015_12 FBgn0011079 l(1)Q34 lethal (1) Q34 http://flybase.net/reports/FBgn0011079.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0266817 CR45279 http://flybase.net/reports/FBgn0266817.html non_protein_coding_gene CR45279 16-Dec-15 2015_12 FBgn0267814 CR46139 http://flybase.net/reports/FBgn0267814.html non_protein_coding_gene CR46139 16-Dec-15 2015_12 FBgn0000738 fs(1)A99 female sterile (1) A99 http://flybase.net/reports/FBgn0000738.html gene fs(1)99 16-Dec-15 2015_12 "female sterile,recessive,cold sensitive,lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage" FBgn0082969 snoRNA:ë¬28S-3316d snoRNA:ë¬28S-3316d http://flybase.net/reports/FBgn0082969.html snoRNA_gene "Psi28S-3316d, psi28S-3316d, CR34552" CR34552 16-Dec-15 2015_12 FBgn0027528 goe gone early http://flybase.net/reports/FBgn0027528.html protein_coding_gene 0004222=metalloendopeptidase activity "0048477=oogenesis, 2000737=negative regulation of stem cell differentiation, 0006508=proteolysis" 0005886=plasma membrane "BcDNA:LD21405, CG9634" "IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13" CG9634 16-Dec-15 2015_12 "viable,fertile" FBgn0266876 CR45337 http://flybase.net/reports/FBgn0266876.html non_protein_coding_gene CR45337 16-Dec-15 2015_12 FBgn0264344 CG43800 http://flybase.net/reports/FBgn0264344.html protein_coding_gene CG43800 16-Dec-15 2015_12 FBgn0035916 GAPsec "GTPase activating protein, SECIS-dependent read-through" http://flybase.net/reports/FBgn0035916.html FBgn0046265 protein_coding_gene 0005096=GTPase activator activity "0006451=translational readthrough, 0043087=regulation of GTPase activity, 0001514=selenocysteine incorporation" "dGAPsec, CG5978, BEST:LD24460" IPR000195=Rab-GTPase-TBC domain CG5978 16-Dec-15 2015_12 WBGene00009726(tbc-13) ENSMUSG00000039678(Tbc1d13) ENSG00000107021(TBC1D13) "viable,fertile" DRSC26128 K -0.104398423 -0.448770259 -0.212651934 -0.282421698 0.188124458 1.631388689 FBgn0264257 Med::smt3 http://flybase.net/reports/FBgn0264257.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0004182 snRNA:U1:82Ea small nuclear RNA U1 at 82Ea http://flybase.net/reports/FBgn0004182.html "FBgn0003915, FBgn0003917" snRNA_gene "0000398=mRNA splicing, via spliceosome" "U1 snRNA, U1, U1 82E(pDm6A), small nuclear RNA U1, U1snRNA82Ea, U1-82.1, U1snRNA, D.U1-2, snRNA:U1, snRNA-U1-82.1, K5, U1b" 16-Dec-15 2015_12 FBgn0053517 Dop2R Dopamine 2-like receptor http://flybase.net/reports/FBgn0053517.html "FBgn0031083, FBgn0031084, FBgn0046542, FBgn0046543, FBgn0046600, FBgn0046601, FBgn0062410" protein_coding_gene "0004952=dopamine neurotransmitter receptor activity, 0001591=dopamine neurotransmitter receptor activity, coupled via Gi/Go, 0004930=G-protein coupled receptor activity, 0008227=G-protein coupled amine receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007212=dopamine receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "dopamine D2 receptor, D[[2]] receptor, anon-WO0170980.131, DD2R, Dop2R, CG9569, dopamine 2-like receptor, D2-like receptor, Dopamine 2-like Receptor, CG17004, D[[2]]-like receptor, D2R, CG33517, anon-WO0170980.130, anon-WO0170980.32, anon-WO0170980.31, dD2R" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000929=Dopamine receptor family" CG33517 16-Dec-15 2015_12 "ENSDARG00000001912(drd4-rs),ENSDARG00000035820(drd4b),ENSDARG00000038363" WBGene00020506(dop-3) ENSXETG00000011662(DRD2) "ENSMUSG00000032259(Drd2),ENSMUSG00000022705(Drd3)" "ENSG00000149295(DRD2),ENSG00000151577(DRD3)" "locomotor behavior defective,feeding behavior defective,viable" FBgn0085214 CG34185 http://flybase.net/reports/FBgn0085214.html protein_coding_gene CG34185 16-Dec-15 2015_12 FBgn0027303 l(1)G0123 lethal (1) G0123 http://flybase.net/reports/FBgn0027303.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0250848 26-29-p 26-29kD-proteinase http://flybase.net/reports/FBgn0250848.html "FBgn0028967, FBgn0024586, FBgn0066875" protein_coding_gene 0004197=cysteine-type endopeptidase activity 0006508=proteolysis "0005875=microtubule associated complex, 0005811=lipid particle" "26-29kd prot, l(3)s3635, anon-SAGE:Wang-123, 26/29kD-proteinase, CG8947, 26,29kDa proteinase, 26-29kDa proteinase, 26-29 kD-proteinase, cathepsin K" "IPR000169=Cysteine peptidase, cysteine active site, IPR013201=Cathepsin propeptide inhibitor domain (I29), IPR000668=Peptidase C1A, papain C-terminal, IPR025661=Cysteine peptidase, asparagine active site, IPR013128=Peptidase C1A, IPR025660=Cysteine peptidase, histidine active site" CG8947 16-Dec-15 2015_12 ENSDARG00000011796(zgc:158580) FBgn0025105 CalpI Calpain I http://flybase.net/reports/FBgn0025105.html gene 0004198=calcium-dependent cysteine-type endopeptidase activity 0006508=proteolysis 16-Dec-15 2015_12 FBgn0264871 CR44062 http://flybase.net/reports/FBgn0264871.html non_protein_coding_gene CR44062 16-Dec-15 2015_12 FBgn0267507 pre-rRNA:CR45847 ribosomal RNA primary transcript:CR45847 http://flybase.net/reports/FBgn0267507.html rRNA_gene CR45847 CR45847 16-Dec-15 2015_12 FBgn0002307 l(3)84Ce lethal (3) 84Ce http://flybase.net/reports/FBgn0002307.html gene 16-Dec-15 2015_12 "lethal,recessive,locomotor behavior defective,flight defective" FBgn0053853 His2A:CG33853 His2A:CG33853 http://flybase.net/reports/FBgn0053853.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33853 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR002119=Histone H2A" CG33853 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0011662 mousse mousse http://flybase.net/reports/FBgn0011662.html gene 0048477=oogenesis 16-Dec-15 2015_12 FBgn0266076 mir-276a mir-276a stem loop http://flybase.net/reports/FBgn0266076.html "FBgn0262439, FBgn0067718, FBgn0067717, FBgn0262294, FBgn0066327" miRNA_gene "0008355=olfactory learning, 0042048=olfactory behavior, 0007611=learning or memory, 0007616=long-term memory" "miR-276a, rosa, CR33584, MiR-276a, 276a, miR-276aS, miR-276, dme-mir-276a, CR33585, mir-276aS, dme-miR-276a-3p, mir-276a, dme-mir-276, CR43001" CR43001 16-Dec-15 2015_12 FBgn0260941 app approximated http://flybase.net/reports/FBgn0260941.html "FBgn0000107, FBgn0036267, FBgn0036268, FBgn0259218" protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" "0007389=pattern specification process, 0007480=imaginal disc-derived leg morphogenesis, 0018345=protein palmitoylation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0042127=regulation of cell proliferation, 0048104=establishment of body hair or bristle planar orientation" "0005783=endoplasmic reticulum, 0045179=apical cortex" "CG17144, CG42318, CG5620, CR32097" "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG42318 16-Dec-15 2015_12 "ENSG00000175048(ZDHHC14),ENSG00000204160(ZDHHC18)" FBgn0061157 l(2)2-L lethal (2) 2-L http://flybase.net/reports/FBgn0061157.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0016938 smi98B smell impaired 98B http://flybase.net/reports/FBgn0016938.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0260110 2L3393 http://flybase.net/reports/FBgn0260110.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0029861 CG3815 http://flybase.net/reports/FBgn0029861.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" 0070822=Sin3-type complex "PF1, Pf1" "IPR000253=Forkhead-associated (FHA) domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR019787=Zinc finger, PHD-finger, IPR001965=Zinc finger, PHD-type" CG3815 16-Dec-15 2015_12 WBGene00008081(athp-1) ENSXETG00000014345(PHF12) ENSMUSG00000037791(Phf12) ENSG00000109118(PHF12) FBgn0001563 l(1)19Fc lethal (1) 19Fc http://flybase.net/reports/FBgn0001563.html gene YT57 16-Dec-15 2015_12 "lethal,recessive" FBgn0000149 aw-b awry b http://flybase.net/reports/FBgn0000149.html gene aw[2] 16-Dec-15 2015_12 "visible,recessive,viable,reduced" wing FBgn0086491 T:Myr-Src42A Myristoylation sequence of Src42A http://flybase.net/reports/FBgn0086491.html engineered_tag "Myristoylation sequence tag 6, myr, T:Myr6" 16-Dec-15 2015_12 FBgn0030814 CG4955 http://flybase.net/reports/FBgn0030814.html FBgn0044528 protein_coding_gene anon-WO0140519.97 CG4955 16-Dec-15 2015_12 viable DRSC19927 K -0.108010329 0.75084093 -0.073309005 0.053746086 0.767701102 1.735888068 FBgn0283457 EC3-12 Enhancer of CCT 3-12 http://flybase.net/reports/FBgn0283457.html gene 16-Dec-15 2015_12 FBgn0013262 E(var)61 E(var)61 http://flybase.net/reports/FBgn0013262.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0024807 DIP1 DISCO Interacting Protein 1 http://flybase.net/reports/FBgn0024807.html protein_coding_gene "0005515=protein binding, 0070883=pre-miRNA binding, 0003725=double-stranded RNA binding, 0003682=chromatin binding" "0098586=cellular response to virus, 0051607=defense response to virus" "0000785=chromatin, 0005737=cytoplasm, 0005634=nucleus" "clot 10495, CG17686, dip1a, TO67, unnamed, klett, TO34, dip1, clot 2020, Disconnected Interacting Protein 1, Ultrabithorax binding protein 1, klt, UbxBP1" IPR014720=Double-stranded RNA-binding domain CG17686 16-Dec-15 2015_12 "fertile,female fertile,visible,lethal,decreased cell number,viable" "eye,head capsule,chaeta,ectopic,antenna,arista,wing,haltere,wing vein,wing margin bristle,capitellum" FBgn0030528 CG11095 http://flybase.net/reports/FBgn0030528.html protein_coding_gene 0016787=hydrolase activity "IPR015797=NUDIX hydrolase domain-like, IPR000086=NUDIX hydrolase domain" CG11095 16-Dec-15 2015_12 ENSDARG00000007722(zgc:153051) YLR151C(PCD1) WBGene00003580(ndx-3) ENSXETG00000021076(NUDT8) ENSMUSG00000024869(Nudt8) ENSG00000167799(NUDT8) viable DRSC26123 K -0.332566449 0.65490444 0.22704819 0.270405551 1.822249871 0.600996586 FBgn0038186 CG14362 http://flybase.net/reports/FBgn0038186.html protein_coding_gene 0005509=calcium ion binding "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG14362 16-Dec-15 2015_12 viable FBgn0022280 l(2)IR30 lethal (2) IR30 http://flybase.net/reports/FBgn0022280.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052241 CG32241 http://flybase.net/reports/FBgn0052241.html protein_coding_gene CG32241 16-Dec-15 2015_12 viable FBgn0261519 did diminished discs http://flybase.net/reports/FBgn0261519.html "FBgn0002506, FBgn0004732" gene "l(3)IX-11, l(3)SG67, l(3)B15, l(3)ds15, l(3)ds-15" 16-Dec-15 2015_12 "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc,cell cycle" FBgn0067740 l(1)G0313 lethal (1) G0313 http://flybase.net/reports/FBgn0067740.html gene 16-Dec-15 2015_12 lethal FBgn0005460 l(1)v463 lethal (1) v463 http://flybase.net/reports/FBgn0005460.html gene l(1)463 16-Dec-15 2015_12 FBgn0030612 CG5599 http://flybase.net/reports/FBgn0030612.html protein_coding_gene 0004147=dihydrolipoamide branched chain acyltransferase activity "0006909=phagocytosis, 0006099=tricarboxylic acid cycle" 0009353=mitochondrial oxoglutarate dehydrogenase complex "IPR001078=2-oxoacid dehydrogenase acyltransferase, catalytic domain, IPR011053=Single hybrid motif, IPR004167=E3-binding domain, IPR003016=2-oxo acid dehydrogenase, lipoyl-binding site, IPR000089=Biotin/lipoyl attachment, IPR015761=Lipoamide Acyltransferase, IPR023213=Chloramphenicol acetyltransferase-like domain" CG5599 16-Dec-15 2015_12 ENSDARG00000040109(dbt) WBGene00014054(ZK669.4) ENSXETG00000013210(dbt) ENSMUSG00000000340(Dbt) ENSG00000137992(DBT) "lethal,recessive,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040691 CG13915 http://flybase.net/reports/FBgn0040691.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039113 CG10217 http://flybase.net/reports/FBgn0039113.html protein_coding_gene 0042060=wound healing CG10217 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0260804 EP3-378 http://flybase.net/reports/FBgn0260804.html gene 16-Dec-15 2015_12 FBgn0041248 Gr23a Gustatory receptor 23a http://flybase.net/reports/FBgn0041248.html FBgn0031445 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gr23A1a, Gustatory receptor 23A.1, CG15396, Gr23aA, Gr23aB, Gr23A1b, 23A1b, 23A.1a, 23A1.b, 23A1a, Gr23a.a, GR23A.1, Gr23a.b, GR23a" IPR013604=7TM chemoreceptor CG15396 16-Dec-15 2015_12 "viable,fertile,visible" mesothoracic tergum FBgn0037521 CG2993 http://flybase.net/reports/FBgn0037521.html protein_coding_gene 0006909=phagocytosis "IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain, IPR014756=Immunoglobulin E-set" CG2993 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" "ENSXETG00000013606(ARRDC2),ENSXETG00000018085(arrdc3),ENSXETG00000002108(ARRDC4),ENSXETG00000011050(TXNIP)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" ENSG00000197070(ARRDC1) lethal FBgn0263843 CR43704 http://flybase.net/reports/FBgn0263843.html non_protein_coding_gene CR43704 16-Dec-15 2015_12 FBgn0026345 Su(rdgB)116 Su(rdgB)116 http://flybase.net/reports/FBgn0026345.html gene 16-Dec-15 2015_12 "retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6" FBgn0036605 CG13041 http://flybase.net/reports/FBgn0036605.html FBgn0047076 protein_coding_gene BcDNA:RE63063 IPR007614=Retinin-like protein CG13041 16-Dec-15 2015_12 FBgn0034454 CG15120 http://flybase.net/reports/FBgn0034454.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR019399=Parkin co-regulated protein" CG15120 16-Dec-15 2015_12 ENSDARG00000004736(pacrg) WBGene00017122(E04F6.2) ENSXETG00000010781(PACRG) ENSMUSG00000037196(Pacrg) ENSG00000112530(PACRG) "viable,fertile" FBgn0267308 CR45744 http://flybase.net/reports/FBgn0267308.html non_protein_coding_gene CR45744 16-Dec-15 2015_12 FBgn0069428 JJF008 JJF008 http://flybase.net/reports/FBgn0069428.html gene 16-Dec-15 2015_12 stress response defective FBgn0265838 CR44627 http://flybase.net/reports/FBgn0265838.html non_protein_coding_gene lincRNA.352 CR44627 16-Dec-15 2015_12 FBgn0053361 5SrRNA:CR33361 5SrRNA:CR33361 http://flybase.net/reports/FBgn0053361.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33361 CR33361 16-Dec-15 2015_12 FBgn0060895 l(3)S044402 lethal (3) S044402 http://flybase.net/reports/FBgn0060895.html gene "0444/02, 444/2" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035312 CG15820 http://flybase.net/reports/FBgn0035312.html FBgn0062888 protein_coding_gene BcDNA:SD08776 "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG15820 16-Dec-15 2015_12 "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" "ENSG00000183569(SERHL2),ENSG00000172250" viable FBgn0016982 snRNA:K2a small nuclear RNA K2a http://flybase.net/reports/FBgn0016982.html snRNA_gene K2a 16-Dec-15 2015_12 FBgn0032405 CG14946 http://flybase.net/reports/FBgn0032405.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002198=Short-chain dehydrogenase/reductase SDR" CG14946 16-Dec-15 2015_12 viable FBgn0023033 l(2)46Ej lethal (2) 46Ej http://flybase.net/reports/FBgn0023033.html gene "Complementation group H, H" 16-Dec-15 2015_12 lethal FBgn0034414 CG15108 http://flybase.net/reports/FBgn0034414.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031698 Ncoa6 Nuclear receptor coactivator 6 http://flybase.net/reports/FBgn0031698.html protein_coding_gene "0035332=positive regulation of hippo signaling, 0051568=histone H3-K4 methylation" 0044666=MLL3/4 complex "dNCOA6, CG14023, NCOA6" CG14023 16-Dec-15 2015_12 ENSXETG00000019466(NCOA6) ENSMUSG00000038369(Ncoa6) ENSG00000198646(NCOA6) "viable,visible" "chaeta,supernumerary" DRSC23060 K 0.820537438 1.67593614 FBgn0040092 lectin-46Cb lectin-46Cb http://flybase.net/reports/FBgn0040092.html FBgn0033444 protein_coding_gene "0005534=galactose binding, 0030246=carbohydrate binding" "0046008=regulation of female receptivity, post-mating, 0046692=sperm competition, 0032504=multicellular organism reproduction, 0008104=protein localization" 0005615=extracellular space "Lectin-46Cb, AC007330b, Lectin 46cb, AC 007330B, lectin46Cb, CG1652" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG1652 16-Dec-15 2015_12 "mating rhythm defective,viable" FBgn0267543 CR45883 http://flybase.net/reports/FBgn0267543.html non_protein_coding_gene CR45883 16-Dec-15 2015_12 FBgn0085685 CG41554 http://flybase.net/reports/FBgn0085685.html FBan0041554 protein_coding_gene 16-Dec-15 2015_12 FBgn0002292 l(3)80Fc lethal (3) 80Fc http://flybase.net/reports/FBgn0002292.html gene "l(3)Lh6, lethal 6, 80Fc, l6" 16-Dec-15 2015_12 lethal FBgn0024605 olfJ78 olfactory J78 http://flybase.net/reports/FBgn0024605.html gene 16-Dec-15 2015_12 smell perception defective FBgn0084046 CG41488 http://flybase.net/reports/FBgn0084046.html FBan0041488 protein_coding_gene 16-Dec-15 2015_12 FBgn0043792 CG30427 http://flybase.net/reports/FBgn0043792.html "FBgn0035081, FBgn0040667, FBgn0050427" protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "0008340=determination of adult lifespan, 0006909=phagocytosis" "CG18680, BEST:LD36843, CG2858" "IPR016040=NAD(P)-binding domain, IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase" CG30427 16-Dec-15 2015_12 "long lived,viable" FBgn0086321 JV166 http://flybase.net/reports/FBgn0086321.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0041093 stau::Mdoa\stau stau http://flybase.net/reports/FBgn0041093.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0259874 Su(Ste):CR42443 Su(Ste):CR42443 http://flybase.net/reports/FBgn0259874.html non_protein_coding_gene CR42443 CR42443 16-Dec-15 2015_12 FBgn0035948 CG5644 http://flybase.net/reports/FBgn0035948.html FBgn0027770 protein_coding_gene anon-EST:Posey104 "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG5644 16-Dec-15 2015_12 viable FBgn0003999 wa warty http://flybase.net/reports/FBgn0003999.html gene 16-Dec-15 2015_12 "visible,male sterile,partially,female sterile,dominant,recessive" "eye,ommatidium,wing" FBgn0263579 mir-4947 mir-4947 stem loop http://flybase.net/reports/FBgn0263579.html miRNA_gene "CR43564, dme-mir-4947" CR43564 16-Dec-15 2015_12 FBgn0031988 CG8668 http://flybase.net/reports/FBgn0031988.html protein_coding_gene "0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" "0008039=synaptic target recognition, 0006486=protein glycosylation" 0016020=membrane "GalT4, Resille, resille, dbeta3GnT" "IPR002659=Glycosyl transferase, family 31" CG8668 16-Dec-15 2015_12 "ENSDARG00000042628(b3galt2),ENSDARG00000070975" WBGene00007104(B0024.15) "ENSMUSG00000043300(B3galnt1),ENSMUSG00000074892(B3galt5),ENSMUSG00000034780(B3galt1),ENSMUSG00000033849(B3galt2)" "ENSG00000169255(B3GALNT1),ENSG00000183778(B3GALT5),ENSG00000172318(B3GALT1),ENSG00000162630(B3GALT2)" viable FBgn0058124 CG40124 http://flybase.net/reports/FBgn0058124.html FBan0040124 protein_coding_gene 16-Dec-15 2015_12 FBgn0011085 l(1)Q43 lethal (1) Q43 http://flybase.net/reports/FBgn0011085.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0020372 TM4SF Transmembrane 4 superfamily http://flybase.net/reports/FBgn0020372.html protein_coding_gene "0016021=integral component of membrane, 0005886=plasma membrane" "CG11303, Dm.Tsp60A" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG11303 16-Dec-15 2015_12 " pupal stage , embryonic stage , adult stage " viable FBgn0002178 l(3)62Bb lethal (3) 62Bb http://flybase.net/reports/FBgn0002178.html gene "l(3)dre9, dre9" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038143 CG9813 http://flybase.net/reports/FBgn0038143.html protein_coding_gene ORE-7 CG9813 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0051259 CG31259 http://flybase.net/reports/FBgn0051259.html FBgn0037593 protein_coding_gene CG11740 IPR026749=Transmembrane protein 135 CG31259 16-Dec-15 2015_12 ENSDARG00000069157(tmem135) WBGene00019345(tmem-135) ENSXETG00000010432() ENSMUSG00000039428(Tmem135) ENSG00000166575(TMEM135) viable FBgn0004191 snRNA:U2:34ABa small nuclear RNA U2 at 34ABa http://flybase.net/reports/FBgn0004191.html "FBgn0003919, FBgn0003921" snRNA_gene "0000398=mRNA splicing, via spliceosome" "0005686=U2 snRNP, 0015030=Cajal body" "U2 snRNA, U2 131A, chr2L:13211901..13212079, K6, D.U2-1, U2snRNA, Dm U2-131A, U2, U2snRNA34ABa, small nuclear RNA U2, snRNA:U2, CR31850, U2:34ABa, U2-34ABa, 34B U2, snRNA-U2-131A, U2-131A, dU2, 131A" CR31850 16-Dec-15 2015_12 "viable,fertile" FBgn0024875 l(2)k00301 lethal (2) k00301 http://flybase.net/reports/FBgn0024875.html gene 16-Dec-15 2015_12 FBgn0000892 fs(1)M91 female sterile (1) M91 http://flybase.net/reports/FBgn0000892.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0060743 l(3)S066208 lethal (3) S066208 http://flybase.net/reports/FBgn0060743.html gene 0662/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0265631 CG44438 http://flybase.net/reports/FBgn0265631.html protein_coding_gene lincRNA.249 CG44438 16-Dec-15 2015_12 FBgn0030156 CG15247 http://flybase.net/reports/FBgn0030156.html protein_coding_gene CG15247 16-Dec-15 2015_12 viable FBgn0062411 Ctr1C Copper transporter 1C http://flybase.net/reports/FBgn0062411.html "FBgn0039813, FBgn0061424" protein_coding_gene 0005375=copper ion transmembrane transporter activity "0006825=copper ion transport, 0015677=copper ion import, 0007283=spermatogenesis, 0035434=copper ion transmembrane transport" "0005886=plasma membrane, 0016021=integral component of membrane" "FBgn0039813, CG15551, BcDNA:AT31946" IPR007274=Ctr copper transporter CG15551 16-Dec-15 2015_12 YHR175W(CTR2) WBGene00017852(F27C1.2) "viable,lethal - all die during larval stage,heat sensitive,some die during second instar larval stage,some die during third instar larval stage,visible" "wing,eye" FBgn0064116 CG33713 http://flybase.net/reports/FBgn0064116.html "FBgn0031172, FBgn0053071, FBgn0053713, FBtr0077228, FBpp0076923, FBtr0077230, FBpp0076925" protein_coding_gene 0000062=fatty-acyl-CoA binding "Dromel_CG33713_FBtr0091704_mORF, CG1704, CG33071ORFB, cg1704, CG33071-ORFB, CG33071" "IPR000582=Acyl-CoA-binding protein, ACBP, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG33713 16-Dec-15 2015_12 ENSDARG00000039456(acbd6) WBGene00011731(acbp-5) ENSXETG00000023141(acbd6) ENSMUSG00000033701(Acbd6) ENSG00000135847(ACBD6) "feeding behavior defective,smell perception defective" FBgn0267165 CR45605 http://flybase.net/reports/FBgn0267165.html non_protein_coding_gene CR45605 16-Dec-15 2015_12 FBgn0024329 Mekk1 Mekk1 http://flybase.net/reports/FBgn0024329.html FBgn0038648 protein_coding_gene "0004709=MAP kinase kinase kinase activity, 0031434=mitogen-activated protein kinase kinase binding, 0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity" "0031452=negative regulation of heterochromatin assembly, 0070059=intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, 0071276=cellular response to cadmium ion, 0034605=cellular response to heat, 0006979=response to oxidative stress, 0002385=mucosal immune response, 0001934=positive regulation of protein phosphorylation, 0071475=cellular hyperosmotic salinity response, 0045793=positive regulation of cell size, 0006468=protein phosphorylation, 0046330=positive regulation of JNK cascade, 0000165=MAPK cascade, 0071243=cellular response to arsenic-containing substance, 0043652=engulfment of apoptotic cell" 0005737=cytoplasm "D-Mekk1, dMEKK, dMEKK4, dMekk1, MEKK1, MEKK4, MEKK, mekk1b, mekk1a, Mekk1/4, CG7717, dMEKK1, DmMEKK1, D-MEKK1, mekk1" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG7717 16-Dec-15 2015_12 "YNR031C(SSK2),YCR073C(SSK22)" WBGene00003472(mtk-1) ENSMUSG00000014426(Map3k4) ENSG00000085511(MAP3K4) "viable,fertile,stress response defective,chemical sensitive,recessive,osmotic stress response defective,heat stress response defective,lethal,conditional,enhancer of variegation,melanotic mass phenotype,nutrition conditional,chemical resistant,visible,cell death defective,immune response defective" "embryonic/larval hindgut,posterior,nutrition conditional,wing,egg chamber,follicle cell" FBgn0028010 l(3)S112110 lethal (3) S112110 http://flybase.net/reports/FBgn0028010.html gene 1121/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0267514 5.8SrRNA-ë¬:CR45854 5.8S ribosomal RNA pseudogene:CR45854 http://flybase.net/reports/FBgn0267514.html pseudogene_attribute CR45854 CR45854 16-Dec-15 2015_12 FBgn0065634 l(2)SH0771 lethal (2) SH0771 http://flybase.net/reports/FBgn0065634.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067645 soft-boiled soft boiled http://flybase.net/reports/FBgn0067645.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "oocyte,germline clone,nurse cell,ectopic" FBgn0010893 l(3)06497 lethal (3) 06497 http://flybase.net/reports/FBgn0010893.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030858 IntS2 Integrator 2 http://flybase.net/reports/FBgn0030858.html protein_coding_gene "0034472=snRNA 3'-end processing, 0022008=neurogenesis, 0016180=snRNA processing" 0032039=integrator complex "Int2, CG8211" "IPR029321=Integrator complex subunit 2, IPR026236=Integrator complex subunit 2, metazoa" CG8211 16-Dec-15 2015_12 ENSDARG00000069085 WBGene00013877(ZC376.6) ENSXETG00000010721(TNeu021n01.1) ENSMUSG00000018068(Ints2) ENSG00000108506(INTS2) "lethal,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell" DRSC20094 IK 0.810254832 -1.904156837 0.430740489 -0.862641018 -1.617064494 -0.557615482 FBgn0041160 comm2 comm2 http://flybase.net/reports/FBgn0041160.html FBgn0036530 protein_coding_gene CG7554 CG7554 16-Dec-15 2015_12 FBgn0052188 CG32188 http://flybase.net/reports/FBgn0052188.html protein_coding_gene CG32188 16-Dec-15 2015_12 DRSC09510 I 0.70342502 1.648947926 0.102321425 0.250448873 -0.564613534 -0.168859109 FBgn0260597 2L3073 http://flybase.net/reports/FBgn0260597.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0037591 Or85c Odorant receptor 85c http://flybase.net/reports/FBgn0037591.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "85A.3, CG17911, 85c, DOR78" "IPR004117=Olfactory receptor, Drosophila" CG17911 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0010370 meso17A mesoderm specific 17A http://flybase.net/reports/FBgn0010370.html gene 0042692=muscle cell differentiation Dmeso17A 16-Dec-15 2015_12 FBgn0038291 CG3984 http://flybase.net/reports/FBgn0038291.html protein_coding_gene CG3984 16-Dec-15 2015_12 viable FBgn0267429 CG45782 http://flybase.net/reports/FBgn0267429.html "FBan0041343, FBgn0085625, FBan0041087, FBgn0069947, FBan0040467, FBgn0069977" protein_coding_gene "Slc45-2, CG41343, GH10292, CG40467, CG41087" IPR020846=Major facilitator superfamily domain CG45782 16-Dec-15 2015_12 FBgn0032709 CG15167 http://flybase.net/reports/FBgn0032709.html protein_coding_gene CG15167 16-Dec-15 2015_12 viable FBgn0015956 l(1)6Ef lethal (1) 6Ef http://flybase.net/reports/FBgn0015956.html gene fs/l 16-Dec-15 2015_12 FBgn0060788 l(3)S059416 lethal (3) S059416 http://flybase.net/reports/FBgn0060788.html gene 0594/16 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0058137 CG40137 http://flybase.net/reports/FBgn0058137.html FBan0040137 protein_coding_gene 16-Dec-15 2015_12 FBgn0005555 l(3)85Fh lethal (3) 85Fh http://flybase.net/reports/FBgn0005555.html gene 16-Dec-15 2015_12 lethal FBgn0065788 l(2)SH0432 lethal (2) SH0432 http://flybase.net/reports/FBgn0065788.html gene l(2)SH2 0432 16-Dec-15 2015_12 "lethal,recessive" FBgn0067304 D12.A D12.A http://flybase.net/reports/FBgn0067304.html gene D12 16-Dec-15 2015_12 "visible,lethal,viable" pigment cell FBgn0259113 DNApol-ë±180 DNA polymerase ë± 180kD http://flybase.net/reports/FBgn0259113.html "FBgn0004493, FBgn0010016, FBgn0041636" protein_coding_gene "0000166=nucleotide binding, 0008296=3'-5'-exodeoxyribonuclease activity, 0008408=3'-5' exonuclease activity, 0003677=DNA binding, 0001882=nucleoside binding, 0003887=DNA-directed DNA polymerase activity" "0006260=DNA replication, 0022008=neurogenesis, 0006271=DNA strand elongation involved in DNA replication, 0006270=DNA replication initiation" "0005634=nucleus, 0005658=alpha DNA polymerase:primase complex" "DNApol-alpha180, Dmpol alpha, polalphap180, pol alpha, DNApola, DNA Pol-alpha180, DNA polymerase-primase 180 kda subunit, DNA polymerase alpha 180 kD, POlalpha 180kDa, Enhancer of mus304, CG6349, DNApolalpha, Pol alpha, 183 kDa pol alpha, DNA polymerase alpha 148,000 alpha subunit, DmPolalpha, 180 kDa subunit, DNA polymerase alpha 182,000 alpha subunit, Pol, polalpha, DNA polymerase alpha, 180 kDa subunit of polymerase-primase, DNA pol 180, DNA-Polalpha, AAB24152, DNA polymerase Alpha 180 kD, DNApol, POLA, DNApolalpha180, DNA polymerase 180K, DNA-polymerase alpha, Polalpha, DNA polalpha, DNApol-alpha, E(mus304)" "IPR023211=DNA polymerase, palm domain, IPR006134=DNA-directed DNA polymerase, family B, multifunctional domain, IPR029702=DNA polymerase alpha catalytic subunit, IPR012337=Ribonuclease H-like domain, IPR006172=DNA-directed DNA polymerase, family B, IPR006133=DNA-directed DNA polymerase, family B, exonuclease domain, IPR024647=DNA polymerase alpha catalytic subunit, N-terminal domain, IPR017964=DNA-directed DNA polymerase, family B, conserved site, IPR015088=Zinc finger, DNA-directed DNA polymerase, family B, alpha" CG6349 16-Dec-15 2015_12 ENSDARG00000045308(pola1) YNL102W(POL1) WBGene00012936(Y47D3A.29) ENSXETG00000021824(POLA1) ENSMUSG00000006678(Pola1) ENSG00000101868(POLA1) " oogenesis stage && adult stage | female , embryonic stage | early " ovary

" larval stage | first instar , adult stage && oogenesis stage , pupal stage | early , embryonic stage | early " " nurse cell

, follicle cell

" DRSC27879 K -0.631856437 1.014294518 -0.258241262 -0.415402757 1.689109282 0.901302761 FBgn0266029 CR44794 http://flybase.net/reports/FBgn0266029.html non_protein_coding_gene CR44794 16-Dec-15 2015_12 FBgn0083123 Uhg5 Uhg5 http://flybase.net/reports/FBgn0083123.html FBgn0259929 non_protein_coding_gene "dUhg-like 5, dUhg5, CR42452" CR42452 16-Dec-15 2015_12 FBgn0038811 CG4159 http://flybase.net/reports/FBgn0038811.html protein_coding_gene "0003723=RNA binding, 0004730=pseudouridylate synthase activity, 0009982=pseudouridine synthase activity" 0001522=pseudouridine synthesis "IPR001406=Pseudouridine synthase I, TruA, IPR020094=Pseudouridine synthase I, TruA, N-terminal, IPR020095=Pseudouridine synthase I, TruA, C-terminal, IPR020103=Pseudouridine synthase, catalytic domain, IPR020097=Pseudouridine synthase I, TruA, alpha/beta domain" CG4159 16-Dec-15 2015_12 ENSDARG00000045562(pus1) "YPL212C(PUS1),YGL063W(PUS2)" WBGene00004248(pus-1) ENSMUSG00000029507(Pus1) ENSG00000177192(PUS1) viable FBgn0058163 CG40163 http://flybase.net/reports/FBgn0058163.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032433 Oatp33Ea Organic anion transporting polypeptide 33Ea http://flybase.net/reports/FBgn0032433.html protein_coding_gene "0005215=transporter activity, 0008514=organic anion transmembrane transporter activity" "0006810=transport, 0015711=organic anion transport" 0016020=membrane "CG5427, oatp 33Ea" "IPR004156=Organic anion transporter polypeptide OATP, IPR002350=Kazal domain, IPR020846=Major facilitator superfamily domain" CG5427 16-Dec-15 2015_12 lethal FBgn0037749 CG9471 http://flybase.net/reports/FBgn0037749.html protein_coding_gene "0004074=biliverdin reductase activity, 0003959=NADPH dehydrogenase activity" 0032504=multicellular organism reproduction "BVR, biliverdin reductase, Biliverdin IX-beta reductase, Biliverdin reductase" IPR016040=NAD(P)-binding domain CG9471 16-Dec-15 2015_12 ENSDARG00000021003(blvrb) "ENSXETG00000016957(),ENSXETG00000002567()" ENSMUSG00000040466(Blvrb) ENSG00000090013(BLVRB) viable FBgn0259425 C18 http://flybase.net/reports/FBgn0259425.html gene 16-Dec-15 2015_12 "visible,lethal" wing hair FBgn0259372 EP-708 http://flybase.net/reports/FBgn0259372.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0033186 CG1602 http://flybase.net/reports/FBgn0033186.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR006578=MADF domain" CG1602 16-Dec-15 2015_12 WBGene00003380(mnm-2) "viable,fertile" FBgn0011618 l(1)K48h-1-2 lethal (1) K48h-1-2 http://flybase.net/reports/FBgn0011618.html gene 16-Dec-15 2015_12 lethal FBgn0000190 Bkd Blackoid http://flybase.net/reports/FBgn0000190.html gene 16-Dec-15 2015_12 "visible,semidominant,body color defective,dominant" FBgn0266460 Dg::shg http://flybase.net/reports/FBgn0266460.html engineered_fusion_gene 16-Dec-15 2015_12 follicle cell FBgn0267910 MRE16 mRNA-like ncRNA in embryogenesis 16 http://flybase.net/reports/FBgn0267910.html "FBgn0086531, FBgn0085364" non_protein_coding_gene "mRNA-like ncRNA in embryogenesis 16, CG34335, CR34335" CR34335 16-Dec-15 2015_12 FBgn0039875 sip3 septin interacting protein 3 http://flybase.net/reports/FBgn0039875.html protein_coding_gene "0008270=zinc ion binding, 0016881=acid-amino acid ligase activity, 0061630=ubiquitin protein ligase activity, 0004842=ubiquitin-protein transferase activity, 0002039=p53 binding" "0030433=ER-associated ubiquitin-dependent protein catabolic process, 0030968=endoplasmic reticulum unfolded protein response, 0016567=protein ubiquitination" "0005783=endoplasmic reticulum, 0016021=integral component of membrane" "Sip3, Synoviolin, dSyno, CG1937, HRD1, Hrd1, septin-interacting protein 3, hrd1" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG1937 16-Dec-15 2015_12 ENSDARG00000017842(syvn1) YOL013C(HRD1) WBGene00004768(sel-11) ENSXETG00000023327(SYVN1) ENSMUSG00000024807(Syvn1) ENSG00000162298(SYVN1) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002681 mat(2)syn-I maternal effect syncytial blastoderm arrest I http://flybase.net/reports/FBgn0002681.html gene "0007349=cellularization, 0007279=pole cell formation" mat(2)synSE10 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0002955 nofK no object fixation K http://flybase.net/reports/FBgn0002955.html gene 16-Dec-15 2015_12 "eye color defective,visual behavior defective" "optic lobe,rhabdomere | adult stage,pigment cell" FBgn0266849 CR45310 http://flybase.net/reports/FBgn0266849.html non_protein_coding_gene CR45310 16-Dec-15 2015_12 FBgn0014303 l(3)h2 lethal (3) h2 http://flybase.net/reports/FBgn0014303.html gene 16-Dec-15 2015_12 FBgn0063377 snoRNA:Me28S-A1666a http://flybase.net/reports/FBgn0063377.html snoRNA_gene "Me28S-A1666a(U76), snoRNA:U76:54Ea, U76snoRNA, CR32889" CR32889 16-Dec-15 2015_12 FBgn0000331 Crimp Crimp http://flybase.net/reports/FBgn0000331.html gene Cm 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" wing FBgn0061105 l(3)S008206b lethal (3) S008206b http://flybase.net/reports/FBgn0061105.html gene 0082/06 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260809 EP3-1729 http://flybase.net/reports/FBgn0260809.html gene 16-Dec-15 2015_12 FBgn0263247 CG43390 http://flybase.net/reports/FBgn0263247.html protein_coding_gene CG43390 16-Dec-15 2015_12 FBgn0266773 CR45238 http://flybase.net/reports/FBgn0266773.html non_protein_coding_gene CR45238 16-Dec-15 2015_12 FBgn0265553 11.158 http://flybase.net/reports/FBgn0265553.html gene 16-Dec-15 2015_12 learning defective FBgn0015625 CycB3 Cyclin B3 http://flybase.net/reports/FBgn0015625.html "FBgn0024564, FBgn0062026" protein_coding_gene "0019901=protein kinase binding, 0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0005515=protein binding" "0000281=mitotic cytokinesis, 0035561=regulation of chromatin binding, 0035186=syncytial blastoderm mitotic cell cycle, 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0007052=mitotic spindle organization, 0010389=regulation of G2/M transition of mitotic cell cycle, 0007067=mitotic nuclear division" 0005634=nucleus "CycB3, Cyc B3, l(3)L6540, anon-WO0118547.414, CyclinB3, cyclin B3, cycB3, CG5814, Cyclin B3" "IPR015452=Cyclin B3, G2/mitotic-specific, IPR004367=Cyclin, C-terminal domain, IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal" CG5814 16-Dec-15 2015_12 "YPR119W(CLB2),YGR108W(CLB1),YPR120C(CLB5),YGR109C(CLB6),YDL155W(CLB3)" ENSXETG00000022597(CCNB3) ENSG00000147082(CCNB3) " embryonic stage | early , embryonic stage , adult stage | female " neuroblast

"lethal,viable,fertile,female sterile,recessive,cytokinesis defective,mitotic cell cycle defective,wild-type" "cell cycle,midbody,anaphase & condensed nuclear chromosome,meiosis I,mitotic cell cycleprd.RG1,mitotic anaphaseprd.RG1" DRSC16618 K 0.198747569 -0.279172755 0.40332787 0.996520882 -1.644900258 -0.490081589 FBgn0030928 CG15044 http://flybase.net/reports/FBgn0030928.html FBgn0047126 protein_coding_gene BcDNA:RE30049 CG15044 16-Dec-15 2015_12 viable FBgn0260767 CG42565 http://flybase.net/reports/FBgn0260767.html "FBgn0034760, FBan0013512" protein_coding_gene CG13512 IPR006629=LPS-induced tumour necrosis factor alpha factor CG42565 16-Dec-15 2015_12 viable FBgn0005485 l(1)ts1480 lethal (1) ts1480 http://flybase.net/reports/FBgn0005485.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0058415 CG40415 http://flybase.net/reports/FBgn0058415.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263946 BG00719 http://flybase.net/reports/FBgn0263946.html gene 16-Dec-15 2015_12 "long lived,male limited,short lived,female limited" FBgn0028254 l(3)82Cb lethal (3) 82Cb http://flybase.net/reports/FBgn0028254.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0061168 l(1)17Cc lethal (1) 17Cc http://flybase.net/reports/FBgn0061168.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002214 l(3)67BDl lethal (3) 67BDl http://flybase.net/reports/FBgn0002214.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0265047 FDY flagrante delicto Y http://flybase.net/reports/FBgn0265047.html "FBgn0064184, FBan0041503, FBgn0085787" protein_coding_gene "CR41503, CG41503, FDY, fdy" IPR006861=Hyaluronan/mRNA-binding protein CG41503 16-Dec-15 2015_12 FBgn0085260 CG34231 http://flybase.net/reports/FBgn0085260.html protein_coding_gene 0000166=nucleotide binding IPR012677=Nucleotide-binding alpha-beta plait domain CG34231 16-Dec-15 2015_12 FBgn0266030 CR44795 http://flybase.net/reports/FBgn0266030.html non_protein_coding_gene CR44795 16-Dec-15 2015_12 FBgn0263830 CG40486 http://flybase.net/reports/FBgn0263830.html "FBgn0069972, FBan0040486, FBgn0031206" protein_coding_gene "0016491=oxidoreductase activity, 0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process "unnamed, FOHSDR, CG12466" "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG40486 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) DRSC20619 IK -0.623051406 -2.013643838 -0.38015867 -0.755220586 -0.355206457 1.750045729 FBgn0264788 CR44018 http://flybase.net/reports/FBgn0264788.html non_protein_coding_gene "lincRNA.741, lincRNA.742" CR44018 16-Dec-15 2015_12 FBgn0043378 EP1121a EP1121a http://flybase.net/reports/FBgn0043378.html gene 16-Dec-15 2015_12 FBgn0025512 fs(3)82EFd fs(3)82EFd http://flybase.net/reports/FBgn0025512.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0030348 CG10352 http://flybase.net/reports/FBgn0030348.html protein_coding_gene "0004721=phosphoprotein phosphatase activity, 0016791=phosphatase activity" 0006470=protein dephosphorylation 0005829=cytosol Phos10352 "IPR023214=HAD-like domain, IPR023215=Nitrophenylphosphatase-like domain, IPR006357=HAD-superfamily hydrolase, subfamily IIA" CG10352 16-Dec-15 2015_12 viable FBgn0042182 CG18749 http://flybase.net/reports/FBgn0042182.html "FBgn0037557, FBgn0051188, FBtr0081799, FBpp0081295, FBtr0081800, FBpp0081296, FBtr0081801, FBpp0081297, FBtr0081802, FBpp0081298" protein_coding_gene "0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0005506=iron ion binding" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process, 0032504=multicellular organism reproduction" "0016222=procollagen-proline 4-dioxygenase complex, 0005576=extracellular region, 0005783=endoplasmic reticulum" "CG31188, CG18238" "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG18749 16-Dec-15 2015_12 "viable,fertile" FBgn0040842 CG15212 http://flybase.net/reports/FBgn0040842.html FBgn0063040 protein_coding_gene BcDNA:RE28658 CG15212 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0033494 KCNQ KCNQ potassium channel http://flybase.net/reports/FBgn0033494.html FBgn0033493 protein_coding_gene "0022843=voltage-gated cation channel activity, 0005249=voltage-gated potassium channel activity, 0005251=delayed rectifier potassium channel activity" "0055085=transmembrane transport, 0006813=potassium ion transport, 0060048=cardiac muscle contraction, 0002027=regulation of heart rate, 0001700=embryonic development via the syncytial blastoderm" "0016021=integral component of membrane, 0008076=voltage-gated potassium channel complex" "CG33135, CG12915, kcnq1, KQT 1, KCNQ-type K[+] channel, CG12215, dKCNQ, DKCNQ, KQT" "IPR003091=Potassium channel, IPR003937=Potassium channel, voltage dependent, KCNQ, IPR028325=Voltage-gated potassium channel, IPR005821=Ion transport domain, IPR013821=Potassium channel, voltage dependent, KCNQ, C-terminal" CG33135 16-Dec-15 2015_12 ENSDARG00000060085(kcnq3) WBGene00002233(kqt-1) ENSXETG00000023036(KCNQ3) "ENSMUSG00000028033(Kcnq5),ENSMUSG00000028631(Kcnq4),ENSMUSG00000016346(Kcnq2)" "ENSG00000185760(KCNQ5),ENSG00000117013(KCNQ4),ENSG00000075043(KCNQ2)" "viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,short lived,female,developmental rate defective,lethal" "cleavage nucleus,maternal effect,adult heart,conditional,adult heart muscle" DRSC06230 I 1.831596872 -0.689739691 -0.565086924 0.170453038 0.293685309 0.060176551 FBgn0022294 l(1)M86.4 lethal (1) M86.4 http://flybase.net/reports/FBgn0022294.html gene M86.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0040972 CG16978 http://flybase.net/reports/FBgn0040972.html protein_coding_gene CT35582 CG16978 16-Dec-15 2015_12 viable FBgn0014956 exu::Dpse\exu1 exu1 http://flybase.net/reports/FBgn0014956.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0003623 Su(var)302 Suppressor of variegation 302 http://flybase.net/reports/FBgn0003623.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable" FBgn0259524 B2004 http://flybase.net/reports/FBgn0259524.html gene 16-Dec-15 2015_12 visible "anterior crossvein,submarginal cell" FBgn0025500 l(3)73An lethal (3) 73An http://flybase.net/reports/FBgn0025500.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259383 C549 http://flybase.net/reports/FBgn0259383.html gene 16-Dec-15 2015_12 visible wing FBgn0043563 Su(hh)IV Su(hh)IV http://flybase.net/reports/FBgn0043563.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0020587 anon-57Cj anon-57Cj http://flybase.net/reports/FBgn0020587.html gene unnamed 16-Dec-15 2015_12 FBgn0263988 Dic61B Dynein intermediate chain at 61B http://flybase.net/reports/FBgn0263988.html "FBgn0035100, FBgn0260009" protein_coding_gene "0042623=ATPase activity, coupled, 0003774=motor activity" "0007283=spermatogenesis, 0007018=microtubule-based movement" "0005858=axonemal dynein complex, 0030286=dynein complex" "CG7051, ms(3)21, male sterile (3) 21, ms" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG7051 16-Dec-15 2015_12 ENSDARG00000044400(wdr78) ENSMUSG00000035126(Wdr78) FBgn0031244 CG11601 http://flybase.net/reports/FBgn0031244.html protein_coding_gene 0016021=integral component of membrane IPR006838=FAR-17a/AIG1-like protein CG11601 16-Dec-15 2015_12 "ENSDARG00000007171(aig1),ENSDARG00000037810(zgc:112175)" "WBGene00007995(C37E2.3),WBGene00007994(C37E2.2)" "ENSXETG00000009792(AIG1),ENSXETG00000019224(C6orf105)" ENSMUSG00000019806(Aig1) ENSG00000146416(AIG1) viable DRSC00318 I 1.687914103 -0.200652215 0.252627309 0.094928164 0.131270734 -1.174901681 FBgn0003181 pys polychaetous http://flybase.net/reports/FBgn0003181.html gene 16-Dec-15 2015_12 "visible,heat sensitive" "macrochaeta,heat sensitive" FBgn0013804 Dew Dew http://flybase.net/reports/FBgn0013804.html gene 16-Dec-15 2015_12 FBgn0261860 CG42789 http://flybase.net/reports/FBgn0261860.html protein_coding_gene "lincRNA.863, DMG8-chr3R.40.015-MIP08885, DMG8-chr3R.40.015" CG42789 16-Dec-15 2015_12 FBgn0022780 Hypnos-1 "Hypoxia, anoxia, sensitive 1" http://flybase.net/reports/FBgn0022780.html gene 0001666=response to hypoxia hypnos-1 16-Dec-15 2015_12 "behavior defective,dominant,neurophysiology defective" adult central nervous system FBgn0035922 Pex7 Peroxin 7 http://flybase.net/reports/FBgn0035922.html protein_coding_gene 0005053=peroxisome matrix targeting signal-2 binding "0007031=peroxisome organization, 0006909=phagocytosis" 0005777=peroxisome "PEX7, CG6486, DmelPex7" "IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG6486 16-Dec-15 2015_12 ENSDARG00000042553(pex7) YDR142C(PEX7) ENSXETG00000027656(pex7) ENSMUSG00000020003(Pex7) ENSG00000112357(PEX7) "viable,body color defective" mesothoracic tergum FBgn0069207 l(2)46CDa lethal (2) 46CDa http://flybase.net/reports/FBgn0069207.html gene Complementation group AA 16-Dec-15 2015_12 "lethal,visible,dominant" wing FBgn0061092 l(3)S011130b lethal (3) S011130b http://flybase.net/reports/FBgn0061092.html gene 0111/30 16-Dec-15 2015_12 "lethal,recessive" FBgn0041770 anon-d34 anon-d34 http://flybase.net/reports/FBgn0041770.html gene d34 16-Dec-15 2015_12 FBgn0250846 glob2 globin 2 http://flybase.net/reports/FBgn0250846.html "FBgn0037458, FBgn0066877" protein_coding_gene "0020037=heme binding, 0019825=oxygen binding, 0005506=iron ion binding" 0015671=oxygen transport 0005634=nucleus "DmeGb2, anon-SAGE:Wang-121, CG15180" "IPR000971=Globin, IPR012292=Globin/Protoglobin, IPR009050=Globin-like" CG15180 16-Dec-15 2015_12 FBgn0000243 Beadexoid Beadexoid http://flybase.net/reports/FBgn0000243.html gene Bxd 16-Dec-15 2015_12 "visible,dominant" wing FBgn0060383 l(3)S134505 lethal (3) S134505 http://flybase.net/reports/FBgn0060383.html gene 1345/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0004499 fs(1)2448 female sterile (1) 2448 http://flybase.net/reports/FBgn0004499.html gene 16-Dec-15 2015_12 FBgn0085477 CG34448 http://flybase.net/reports/FBgn0085477.html "FBgn0031427, FBan0031684, FBgn0051684" protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process "CG31684, CG9966" "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG34448 16-Dec-15 2015_12 FBgn0037645 CG11966 http://flybase.net/reports/FBgn0037645.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG11966 16-Dec-15 2015_12 "WBGene00003845(odd-1),WBGene00003846(odd-2)" "lethal,increased cell death" "ventral nerve cord,ventral nerve cord commissure,ventral midline,eye" FBgn0042648 elav::Hsap\ELAVL4 ELAVL4 http://flybase.net/reports/FBgn0042648.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0014121 anon-96Ff anon-96Ff http://flybase.net/reports/FBgn0014121.html gene X transcript 16-Dec-15 2015_12 larval stage eye-antennal disc

FBgn0085261 CG34232 http://flybase.net/reports/FBgn0085261.html protein_coding_gene CG34232 16-Dec-15 2015_12 FBgn0086451 l(2)k09022 lethal (2) k09022 http://flybase.net/reports/FBgn0086451.html "FBgn0031864, FBgn0022017, FBgn0062204" protein_coding_gene "0009267=cellular response to starvation, 0022008=neurogenesis" "anon-WO0118547.160, CG10805" "IPR022125=U3 small nucleolar RNA-associated protein 10, IPR012954=BP28, C-terminal domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG10805 16-Dec-15 2015_12 "ENSDARG00000071707(heatr1),ENSDARG00000020671(LOC100151449)" YJL109C(UTP10) WBGene00022739(toe-1) ENSXETG00000009013(HEATR1) ENSMUSG00000050244(Heatr1) ENSG00000119285(HEATR1) FBgn0266371 CR45015 http://flybase.net/reports/FBgn0266371.html non_protein_coding_gene CR45015 16-Dec-15 2015_12 FBgn0065293 l(2)SH2003 lethal (2) SH2003 http://flybase.net/reports/FBgn0065293.html gene l(2)SH2 2003 16-Dec-15 2015_12 "lethal,recessive" FBgn0021973 l(2)k09935 lethal (2) k09935 http://flybase.net/reports/FBgn0021973.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061504 l(2)44Fl lethal (2) 44Fl http://flybase.net/reports/FBgn0061504.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266065 CR44818 http://flybase.net/reports/FBgn0266065.html non_protein_coding_gene CR44818 16-Dec-15 2015_12 FBgn0024687 jok just odd knobs http://flybase.net/reports/FBgn0024687.html gene 0001746=Bolwig's organ morphogenesis 16-Dec-15 2015_12 viable "Bolwig nerve,photoreceptor cell" FBgn0264826 CR44034 http://flybase.net/reports/FBgn0264826.html non_protein_coding_gene CR44034 16-Dec-15 2015_12 FBgn0016640 ER2-4 ER2-4 http://flybase.net/reports/FBgn0016640.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023148 Su(mg)3-4 Suppressor of modifier of gypsy 3-4 http://flybase.net/reports/FBgn0023148.html gene 16-Dec-15 2015_12 FBgn0267130 CR45570 http://flybase.net/reports/FBgn0267130.html non_protein_coding_gene CR45570 16-Dec-15 2015_12 FBgn0036494 Toll-6 Toll-6 http://flybase.net/reports/FBgn0036494.html protein_coding_gene "0004888=transmembrane signaling receptor activity, 0005030=neurotrophin receptor activity" "0007165=signal transduction, 0003401=axis elongation, 0060026=convergent extension, 0006952=defense response" "0005886=plasma membrane, 0016021=integral component of membrane" "dTLR6, Toll 6, toll-6, toll receptor, CG7250, Tl-6, dToll6, 18w-like, CT22359, TOLL 6, toll" "IPR000372=Leucine-rich repeat N-terminal domain, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG7250 16-Dec-15 2015_12 WBGene00006593(tol-1) "ENSXETG00000021933(),ENSXETG00000017689(),ENSXETG00000021898()" ENSMUSG00000033777(Tlr13) ENSG00000100399(CHADL) " embryonic stage , embryonic stage -- adult stage " "lethal,viable,fertile,neuroanatomy defective,decreased cell death,visible" "adult abdomen,macrochaeta,ectopic,eye,wing vein,leg,wing,wing disc,embryonic/larval central nervous system,trichogen cell" DRSC11304 E 1.373948068 0.469184431 3.237089089 0.088044673 1.488651526 -0.111272897 FBgn0011774 Irbp Inverted repeat-binding protein http://flybase.net/reports/FBgn0011774.html "FBgn0004048, FBgn0011292" protein_coding_gene "0004003=ATP-dependent DNA helicase activity, 0046982=protein heterodimerization activity, 0004677=DNA-dependent protein kinase activity, 0042162=telomeric DNA binding, 0003677=DNA binding, 0003684=damaged DNA binding" "0000723=telomere maintenance, 0006303=double-strand break repair via nonhomologous end joining" "0005634=nucleus, 0043564=Ku70:Ku80 complex" "IRBP/Ku70, YPF1, dp70, p70, YPF1beta, Ypf1b, Yolk protein factor 1b, irbp, DmKu70, Ku70, ku70, IRBP, CG5247, Ku" "IPR016194=SPOC-like, C-terminal domain, IPR006165=Ku70, IPR005160=Ku70/Ku80 C-terminal arm, IPR002035=von Willebrand factor, type A, IPR005161=Ku70/Ku80, N-terminal alpha/beta, IPR006164=Ku70/Ku80 beta-barrel domain" CG5247 16-Dec-15 2015_12 ENSDARG00000071551(xrcc6) WBGene00000519(cku-70) ENSXETG00000004548(xrcc6) ENSMUSG00000022471(Xrcc6) ENSG00000196419(XRCC6) "radiation sensitive,recessive,chemical sensitive,visible,wild-type,viable" "macrochaeta,supernumerary,adult thoracic sensillum" FBgn0015944 gang-of-three gang of three http://flybase.net/reports/FBgn0015944.html gene 16-Dec-15 2015_12 FBgn0014177 ftz::Scr ftz::Scr http://flybase.net/reports/FBgn0014177.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0032986 CG3262 http://flybase.net/reports/FBgn0032986.html FBan0003262 protein_coding_gene "0005524=ATP binding, 0000166=nucleotide binding" "IPR019591=Mrp/NBP35 ATP-binding protein, IPR000808=Mrp, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3262 16-Dec-15 2015_12 ENSDARG00000054821(nubpl) ENSXETG00000014129(TEgg017a12.1) ENSMUSG00000035142(Nubpl) ENSG00000151413(NUBPL) FBgn0034768 Obp58b Odorant-binding protein 58b http://flybase.net/reports/FBgn0034768.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "Odorant binding protein 58b, C13518, DmelObp58b, CG13518" IPR006170=Pheromone/general odorant binding protein CG13518 16-Dec-15 2015_12 viable FBgn0033371 CNT1 Concentrative Nucleoside Transporter 1 http://flybase.net/reports/FBgn0033371.html protein_coding_gene 0005415=nucleoside:sodium symporter activity 0006810=transport 0016020=membrane "DmCnt1, CG11778" "IPR008276=Concentrative nucleoside transporter, IPR011657=Concentrative nucleoside transporter C-terminal domain, IPR002668=Concentrative nucleoside transporter N-terminal domain" CG11778 16-Dec-15 2015_12 ENSDARG00000060879(si:dkey-24l11.1) "WBGene00017868(F27E11.2),WBGene00017867(F27E11.1)" "ENSXETG00000011724(SLC28A3),ENSXETG00000009806()" "ENSMUSG00000027219(Slc28a2),ENSMUSG00000079071(Gm14085),ENSMUSG00000025726(Slc28a1),ENSMUSG00000021553(Slc28a3)" "ENSG00000137860(SLC28A2),ENSG00000156222(SLC28A1),ENSG00000197506(SLC28A3)" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC06082 K -0.214426719 0.426565797 0.73561061 -0.144935321 1.230353934 -1.679888064 FBgn0044810 TotX Turandot X http://flybase.net/reports/FBgn0044810.html FBgn0051193 protein_coding_gene "0009617=response to bacterium, 0034605=cellular response to heat, 0034599=cellular response to oxidative stress" "0005576=extracellular region, 0005615=extracellular space" "tot, Turandot, Tot X, TOTX, CG31193" IPR010825=Stress-inducible humoral factor Turandot CG31193 16-Dec-15 2015_12 FBgn0070002 BG01572 BG01572 http://flybase.net/reports/FBgn0070002.html gene 16-Dec-15 2015_12 stress response defective FBgn0022214 l(2)k03706 lethal (2) k03706 http://flybase.net/reports/FBgn0022214.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031697 CG14024 http://flybase.net/reports/FBgn0031697.html protein_coding_gene 0016232=HNK-1 sulfotransferase activity 0016051=carbohydrate biosynthetic process 0016021=integral component of membrane d4ST1 "IPR005331=Sulfotransferase, IPR018011=Carbohydrate sulfotransferase-related" CG14024 16-Dec-15 2015_12 viable FBgn0065692 l(2)SH0642 lethal (2) SH0642 http://flybase.net/reports/FBgn0065692.html gene l(2)SH2 0642 16-Dec-15 2015_12 "lethal,recessive" FBgn0260100 2L0058 http://flybase.net/reports/FBgn0260100.html gene "0035001=dorsal trunk growth, open tracheal system" 16-Dec-15 2015_12 "cell lethalcell lethal,somatic clone" embryonic/larval dorsal trunk FBgn0037371 Sym Symplekin http://flybase.net/reports/FBgn0037371.html protein_coding_gene 0003677=DNA binding "0006378=mRNA polyadenylation, 0006398=histone mRNA 3'-end processing, 0006379=mRNA cleavage" "0005923=bicellular tight junction, 0005848=mRNA cleavage stimulating factor complex, 0005634=nucleus" "Symplekin, CG2097, Symp, dSymp, symplekin" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR022075=Symplekin C-terminal, IPR021850=Symplekin/Pta1" CG2097 16-Dec-15 2015_12 ENSDARG00000059553(si:dkeyp-117b8.1) YAL043C(PTA1) WBGene00017797(symk-1) ENSXETG00000024453(sympk) ENSMUSG00000023118(Sympk) ENSG00000125755(SYMPK) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026720 fs(1)pyr fs(1)pyr http://flybase.net/reports/FBgn0026720.html gene 16-Dec-15 2015_12 FBgn0267952 CR46232 http://flybase.net/reports/FBgn0267952.html pseudogene_attribute lincRNA.880 CR46232 16-Dec-15 2015_12 FBgn0002021 l(2)37Bb lethal (2) 37Bb http://flybase.net/reports/FBgn0002021.html FBgn0032747 protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process "l(2)35B2, l(2)E58, Bb, CG10655" IPR006076=FAD dependent oxidoreductase CG10655 16-Dec-15 2015_12 ENSDARG00000060790 WBGene00010847(M04B2.4) ENSXETG00000000843(FOXRED1) ENSMUSG00000039048(Foxred1) "lethal,recessive,wild-type,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,viable,female fertile,female sterile" "adult thorax,imaginal disc,embryonic/larval salivary gland,embryonic/larval fat body" FBgn0060845 l(3)S049009b lethal (3) S049009b http://flybase.net/reports/FBgn0060845.html gene 0490/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0082931 snoRNA:Me28S-G2703a snoRNA:Me28S-G2703a http://flybase.net/reports/FBgn0082931.html snoRNA_gene "Me28S-Gm2703a, Me28S-G2703a, CR34539, chr2R:10138338..10138435" CR34539 16-Dec-15 2015_12 FBgn0029931 CG14427 http://flybase.net/reports/FBgn0029931.html protein_coding_gene CG14427 16-Dec-15 2015_12 "viable,fertile" FBgn0016793 dog dog of glass http://flybase.net/reports/FBgn0016793.html gene 0042051=compound eye photoreceptor development 16-Dec-15 2015_12 FBgn0265367 CR44308 http://flybase.net/reports/FBgn0265367.html non_protein_coding_gene lincRNA.21 CR44308 16-Dec-15 2015_12 FBgn0002266 l(3)69Ae lethal (3) 69Ae http://flybase.net/reports/FBgn0002266.html gene "rsg28, rose-gespleten region interval 28, l(3)rsg28" 16-Dec-15 2015_12 lethal FBgn0039663 CG2321 http://flybase.net/reports/FBgn0039663.html protein_coding_gene "IPR029269=Putative treble-clef, zinc-finger domain, IPR026049=Uncharacterised protein C2orf42" CG2321 16-Dec-15 2015_12 ENSDARG00000059636(si:ch211-127d4.3) ENSXETG00000008515(C2orf42) ENSMUSG00000046679(C87436) ENSG00000115998(C2orf42) "viable,visible" trichogen cell FBgn0266938 CR45389 http://flybase.net/reports/FBgn0266938.html non_protein_coding_gene CR45389 16-Dec-15 2015_12 FBgn0264827 CR44035 http://flybase.net/reports/FBgn0264827.html non_protein_coding_gene CR44035 16-Dec-15 2015_12 FBgn0001421 l(1)6De lethal (1) 6De http://flybase.net/reports/FBgn0001421.html gene l(1)EM25 16-Dec-15 2015_12 "lethal,recessive" FBgn0005461 l(1)ts13 lethal (1) ts13 http://flybase.net/reports/FBgn0005461.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0028056 l(3)S094310 lethal (3) S094310 http://flybase.net/reports/FBgn0028056.html gene "0943/10, 943/10" 16-Dec-15 2015_12 "lethal,recessive" FBgn0011962 tRNA:R2:84Fd transfer RNA:arg2:84Fd http://flybase.net/reports/FBgn0011962.html "FBgn0003758, FBgn0011947, FBgn0051585, FBgn0060094" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033429=CGU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Arg][[2]], tRNA:R:ACG:AE002708-d, AE002708.trna65-ArgACG, CR31585, chr3R.trna71-ArgACG, tRNA[arg], tRNA:arg1, tRNA:R1, transfer RNA:arg1, tRNA:arg2:84Fd" CR31585 16-Dec-15 2015_12 FBgn0051226 CG31226 http://flybase.net/reports/FBgn0051226.html "FBgn0045296, FBgn0047329" protein_coding_gene "NEST:bs14h12, BcDNA:AT26083" CG31226 16-Dec-15 2015_12 viable DRSC21724 I -1.672918703 0.560440944 -0.278229012 0.457068063 1.086903024 -0.604963711 FBgn0004372 aly always early http://flybase.net/reports/FBgn0004372.html "FBgn0013662, FBgn0014354, FBgn0035387" protein_coding_gene 0005515=protein binding "0007141=male meiosis I, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006325=chromatin organization, 0006352=DNA-templated transcription, initiation, 0007283=spermatogenesis, 0048515=spermatid differentiation, 0051039=positive regulation of transcription during meiosis, 0007126=meiotic nuclear division, 0010468=regulation of gene expression, 0007286=spermatid development" "0005634=nucleus, 0017053=transcriptional repressor complex, 0000790=nuclear chromatin, 0005737=cytoplasm, 0000785=chromatin" "ms(3)ry2, 143450_at, ms(3)2, CG2075, Aly, Always early" IPR010561=Protein LIN-9/Protein ALWAYS EARLY CG2075 16-Dec-15 2015_12 ENSMUSG00000058729(Lin9) " adult stage | male , adult stage " " spermatocyte

, spermatid

" "viable,male sterile,fertile,recessive,meiotic cell cycle defective,lethal,heat sensitive" "testis,spermatocyte,nuclear chromosome & primary spermatocyte,heat sensitive" FBgn0052064 S-Lap4 Sperm-Leucylaminopeptidase 4 http://flybase.net/reports/FBgn0052064.html "FBgn0036084, FBgn0044648, FBgn0044739" protein_coding_gene "0008235=metalloexopeptidase activity, 0004177=aminopeptidase activity, 0030145=manganese ion binding" 0006508=proteolysis 0005737=cytoplasm "S-LAP 4, anon-WO0140519.141, Sperm-LeucylAminoPeptidase 4, anon-WO0140519.223, CG32064, GH8, CG8040, bs04d09.y1" "IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal" CG32064 16-Dec-15 2015_12 viable DRSC10957 K -0.121583999 -0.026079136 0.166756726 0.554619282 -1.547797407 -1.251004022 FBgn0037563 CG11672 http://flybase.net/reports/FBgn0037563.html FBgn0063043 protein_coding_gene BcDNA:RE26525 CG11672 16-Dec-15 2015_12 viable FBgn0051179 CG31179 http://flybase.net/reports/FBgn0051179.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0003629 Su(var)320 Suppressor of variegation 320 http://flybase.net/reports/FBgn0003629.html gene 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant" FBgn0044392 Scim36 Sensitized chromosome inheritance modifier 36 http://flybase.net/reports/FBgn0044392.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0265310 CR44283 http://flybase.net/reports/FBgn0265310.html non_protein_coding_gene CR44283 16-Dec-15 2015_12 FBgn0058153 CG40153 http://flybase.net/reports/FBgn0058153.html FBan0040153 protein_coding_gene 16-Dec-15 2015_12 FBgn0035945 CG5026 http://flybase.net/reports/FBgn0035945.html protein_coding_gene "0004438=phosphatidylinositol-3-phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity" 0046856=phosphatidylinositol dephosphorylation 0005737=cytoplasm # CG5026 "IPR010569=Myotubularin-like phosphatase domain, IPR030564=Myotubularin family, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR029021=Protein-tyrosine phosphatase-like" CG5026 16-Dec-15 2015_12 "ENSDARG00000001214(zgc:154055),ENSDARG00000015860(mtmr9)" WBGene00003479(mtm-9) "ENSXETG00000000685(MTMR9),ENSXETG00000005248()" ENSMUSG00000035078(Mtmr9) ENSG00000104643(MTMR9) "viable,fertile" FBgn0020860 curl-r "curl, recessive" http://flybase.net/reports/FBgn0020860.html gene curl 16-Dec-15 2015_12 FBgn0086080 snoRNA:Me28S-A576 http://flybase.net/reports/FBgn0086080.html snoRNA_gene "CR34709, Me28S-Am576" CR34709 16-Dec-15 2015_12 FBgn0014957 exu::Dpse\exu2 exu2 http://flybase.net/reports/FBgn0014957.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0261271 esi-1 endogenous siRNA 1 http://flybase.net/reports/FBgn0261271.html gene "hp-CG18854A, hp-CG18854, esi-1.2, esiRNA-sl-1, esi-1.1" 16-Dec-15 2015_12 FBgn0020824 l(3)98Dc lethal (3) 98Dc http://flybase.net/reports/FBgn0020824.html gene "l(3)98D-Ec, l(3)M3-18, M318" 16-Dec-15 2015_12 "lethal,recessive" FBgn0037773 CG5359 http://flybase.net/reports/FBgn0037773.html FBgn0063024 protein_coding_gene BcDNA:RE37471 IPR005334=Tctex-1 CG5359 16-Dec-15 2015_12 ENSDARG00000054255(si:ch211-276k2.4) WBGene00017014(dylt-2) "ENSXETG00000006790(BC080499.1),ENSXETG00000010979(TCTEX1D4)" ENSMUSG00000014075(Tctex1d2) ENSG00000213123(TCTEX1D2) "viable,fertile" DRSC15780 I 2.685271928 -0.003681487 -0.153713919 0.452736011 0.427391403 -0.921163961 FBgn0030319 CG2533 http://flybase.net/reports/FBgn0030319.html FBgn0063703 protein_coding_gene BcDNA:AT28768 CG2533 16-Dec-15 2015_12 "viable,fertile" DRSC19855 K -0.008256799 0.501565821 -0.223310805 0.141557683 0.085907201 -2.032097368 FBgn0036667 CG9669 http://flybase.net/reports/FBgn0036667.html protein_coding_gene IPR007915=Uncharacterised protein family UPF0197 CG9669 16-Dec-15 2015_12 WBGene00021960(Y57E12AM.1) ENSXETG00000027540(Q6DDB3_XENTR) ENSMUSG00000036372(1810006K21Rik) ENSG00000134825(C11orf10) FBgn0020053 E(wa)818 E(wa)818 http://flybase.net/reports/FBgn0020053.html gene E818 16-Dec-15 2015_12 "lethal,recessive,eye color defective" pigment cell FBgn0060517 l(3)S103705b lethal (3) S103705b http://flybase.net/reports/FBgn0060517.html gene 1037/05 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0069350 Suppressor-of-Punch Suppressor of Punch http://flybase.net/reports/FBgn0069350.html gene 0042416=dopamine biosynthetic process 16-Dec-15 2015_12 FBgn0044110 E(rst)C349 E(rst)C349 http://flybase.net/reports/FBgn0044110.html gene 0001745=compound eye morphogenesis C349 16-Dec-15 2015_12 viable FBgn0003374 Sgs4 Salivary gland secretion 4 http://flybase.net/reports/FBgn0003374.html protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "CG12181, EG:96G10.6, sgs4, sgs-4, SGS4, SGS-4, Sgs-4, salivary gland secretion protein 4, Sgs" CG12181 16-Dec-15 2015_12 larval stage | late third instar larval stage organism

larval stage | late third instar larval stage embryonic/larval salivary gland

electrophoretic variant FBgn0037449 CG15185 http://flybase.net/reports/FBgn0037449.html protein_coding_gene CG15185 16-Dec-15 2015_12 viable FBgn0030817 CG4991 http://flybase.net/reports/FBgn0030817.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport CT15971 "IPR013057=Amino acid transporter, transmembrane domain" CG4991 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" viable FBgn0001216 Hsc70-1 Heat shock protein cognate 1 http://flybase.net/reports/FBgn0001216.html FBgn0064802 protein_coding_gene "0016887=ATPase activity, 0051082=unfolded protein binding" "0006457=protein folding, 0009408=response to heat" "0005875=microtubule associated complex, 0005739=mitochondrion, 0005811=lipid particle" "heat shock protein cognate 1, HSP7A_DROME, BcDNA:RH49358, HSC1, HSC70, Hsp-c1, DmHsp70, HSC70-1, HSC-70, hsc70, 143191_at, dhsc70, CG8937, dhsc70-1, Hsc1, Hsc70" "IPR013126=Heat shock protein 70 family, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site" CG8937 16-Dec-15 2015_12 "YBL075C(SSA3),YAL005C(SSA1),YLL024C(SSA2),YER103W(SSA4)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC11185 EK 0.36346297 -0.077429705 -0.08715295 -1.884926168 0.679487716 -1.532617542 FBgn0003494 split-thorax split thorax http://flybase.net/reports/FBgn0003494.html gene spx 16-Dec-15 2015_12 "visible,viable,male,reduced,male fertile,female,poor,female fertile" "adult thorax,eye,wing,tergite" FBgn0031004 CG7992 http://flybase.net/reports/FBgn0031004.html protein_coding_gene CG7992 16-Dec-15 2015_12 "viable,fertile" FBgn0264875 CR44066 http://flybase.net/reports/FBgn0264875.html non_protein_coding_gene CR44066 16-Dec-15 2015_12 FBgn0019744 l(1)89B lethal (1) 89B http://flybase.net/reports/FBgn0019744.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061499 l(2)45An lethal (2) 45An http://flybase.net/reports/FBgn0061499.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052753 CR32753 http://flybase.net/reports/FBgn0052753.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0041105 nerfin-2 nervous fingers 2 http://flybase.net/reports/FBgn0041105.html FBgn0037785 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "Nerfin, Nervous Fingers, CG12809" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG12809 16-Dec-15 2015_12 FBgn0259331 EP-3 http://flybase.net/reports/FBgn0259331.html gene 16-Dec-15 2015_12 "visible,lethal" wing vein FBgn0084011 CG41447 http://flybase.net/reports/FBgn0084011.html FBan0041447 protein_coding_gene 16-Dec-15 2015_12 FBgn0034047 CG12970 http://flybase.net/reports/FBgn0034047.html protein_coding_gene IPR024810=Mab-21 domain CG12970 16-Dec-15 2015_12 "viable,visible" "trichogen cell,supernumerary" FBgn0260646 CG42538 http://flybase.net/reports/FBgn0260646.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42538 16-Dec-15 2015_12 FBgn0000267 cbf clubfoot http://flybase.net/reports/FBgn0000267.html gene 16-Dec-15 2015_12 "visible,recessive" "leg,tarsal segment,wing" FBgn0060918 l(3)S042606 lethal (3) S042606 http://flybase.net/reports/FBgn0060918.html gene 0426/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0013315 Pbp27 Phenylalkylamine binding protein-27kD http://flybase.net/reports/FBgn0013315.html gene 0008145=phenylalkylamine binding 16-Dec-15 2015_12 adult stage adult head

FBgn0265372 CR44313 http://flybase.net/reports/FBgn0265372.html non_protein_coding_gene lincRNA.290 CR44313 16-Dec-15 2015_12 FBgn0038942 CG13862 http://flybase.net/reports/FBgn0038942.html protein_coding_gene CG13862 16-Dec-15 2015_12 viable FBgn0031694 Cyp4ac2 Cyp4ac2 http://flybase.net/reports/FBgn0031694.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0042445=hormone metabolic process, 0046701=insecticide catabolic process" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "cytochrome P450, CG17970, 4ac2" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG17970 16-Dec-15 2015_12 YDR402C(DIT2) viable DRSC03303 K -0.997974232 0.37023727 -0.235738006 -0.507348396 -0.209930826 -2.070454368 FBgn0044344 springer\env env http://flybase.net/reports/FBgn0044344.html transposable_element_gene ORF3 IPR009882=Gypsy 16-Dec-15 2015_12 FBgn0040653 IM4 Immune induced molecule 4 http://flybase.net/reports/FBgn0040653.html FBgn0047029 protein_coding_gene "0006955=immune response, 0009617=response to bacterium, 0006959=humoral immune response, 0006952=defense response, 0000902=cell morphogenesis" "0005576=extracellular region, 0005615=extracellular space" "BcDNA:RH25931, DIM-4, CG15231, DIM 4, immune induced peptide 4, DIM4, Drosophila immune-induced molecule 4" CG15231 16-Dec-15 2015_12 "viable,fertile" FBgn0066128 E(sda)F E(sda)F http://flybase.net/reports/FBgn0066128.html gene "0009612=response to mechanical stimulus, 0007638=mechanosensory behavior" Line F 16-Dec-15 2015_12 bang sensitive FBgn0019886 Letm1 LETM1 ortholog http://flybase.net/reports/FBgn0019886.html protein_coding_gene "0005432=calcium:sodium antiporter activity, 0015386=potassium:proton antiporter activity, 0005509=calcium ion binding" "0071456=cellular response to hypoxia, 0006851=mitochondrial calcium ion transport, 0070584=mitochondrion morphogenesis, 0007269=neurotransmitter secretion" "0031966=mitochondrial membrane, 0005739=mitochondrion" "Letm1, DmLETM1, unnamed, CG4589, dLetm1, anon-60Da, B4D, anon60Da" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR011685=LETM1-like" CG4589 16-Dec-15 2015_12 ENSDARG00000056978(letm1) WBGene00010279(letm-1) ENSMUSG00000005299(Letm1) ENSG00000168924(LETM1) "partially lethal - majority die,some die during pupal stage,lethal - all die before end of P-stage,locomotor behavior defective,viable,neurophysiology defective,lethal - all die during first instar larval stage,lethal - all die before end of larval stage,lethal,some die during P-stage,small body,flightless,visible" "eye,eye disc,ommatidium | third instar larval stage,photoreceptor cell | third instar larval stage,mitochondrioney.PH,embryonic/larval neuromuscular junction" FBgn0025807 Rad9 Rad9 http://flybase.net/reports/FBgn0025807.html protein_coding_gene "0006281=DNA repair, 0000077=DNA damage checkpoint" "0031965=nuclear membrane, 0030896=checkpoint clamp complex, 0005634=nucleus" "rad9, CG3945, DmRad9" "IPR026584=Rad9, IPR007268=Rad9/Ddc1" CG3945 16-Dec-15 2015_12 ENSDARG00000056984(zgc:56197) WBGene00001997(hpr-9) "ENSXETG00000015759(Q6DJ26_XENTR),ENSXETG00000020936(RAD9B)" "ENSMUSG00000024824(Rad9),ENSMUSG00000038569(Rad9b)" "ENSG00000172613(RAD9A),ENSG00000151164(RAD9B)" "viable,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039486 caix caix http://flybase.net/reports/FBgn0039486.html protein_coding_gene "0004089=carbonate dehydratase activity, 0008270=zinc ion binding" 0006730=one-carbon metabolic process "CG6074, CAIX, CT19053" "IPR018338=Carbonic anhydrase, alpha-class, conserved site, IPR023561=Carbonic anhydrase, alpha-class, IPR001148=Alpha carbonic anhydrase" CG6074 16-Dec-15 2015_12 ENSDARG00000042293(ca4b) WBGene00000283(cah-5) "ENSXETG00000022384(),ENSXETG00000016426(CA14)" "ENSMUSG00000079715,ENSMUSG00000028463(Car9)" "lethal,viable" FBgn0000048 ad arcoid http://flybase.net/reports/FBgn0000048.html gene archoid 16-Dec-15 2015_12 "visible,recessive" "wing,crossvein,leg,mesothoracic suture" FBgn0002239 l(3)68Ca lethal (3) 68Ca http://flybase.net/reports/FBgn0002239.html gene l(3)v4-2 16-Dec-15 2015_12 "partially lethal - majority die,heat sensitive" FBgn0267610 CR45948 http://flybase.net/reports/FBgn0267610.html pseudogene_attribute CR45948 16-Dec-15 2015_12 FBgn0040660 CG13551 http://flybase.net/reports/FBgn0040660.html FBgn0047117 protein_coding_gene 0004857=enzyme inhibitor activity "0045980=negative regulation of nucleotide metabolic process, 0050830=defense response to Gram-positive bacterium" 0005739=mitochondrion "BcDNA:RE33866, SK[[66]]" "IPR007648=ATPase inhibitor, IATP, mitochondria" CG13551 16-Dec-15 2015_12 "ENSDARG00000067975(zgc:162207),ENSDARG00000044092(si:ch211-15d5.5)" WBGene00015248(mai-2) ENSXETG00000007103() ENSMUSG00000054428(Atpif1) ENSG00000130770(ATPIF1) viable FBgn0013385 acj9 abnormal-chemosensory-jump-9 http://flybase.net/reports/FBgn0013385.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive" FBgn0259292 EP-603 http://flybase.net/reports/FBgn0259292.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0025932 hip34 hb-interacting protein 34 http://flybase.net/reports/FBgn0025932.html gene 16-Dec-15 2015_12 FBgn0046659 anon-38C.50 anon-38C.50 http://flybase.net/reports/FBgn0046659.html gene 38C.50 16-Dec-15 2015_12 FBgn0266538 CG45099 http://flybase.net/reports/FBgn0266538.html protein_coding_gene CG45099 16-Dec-15 2015_12 FBgn0000958 fs(2)E5 female sterile (2) E5 http://flybase.net/reports/FBgn0000958.html gene fs2.5 16-Dec-15 2015_12 "female semi-sterile,recessive,female sterile" egg FBgn0000589 E(SD) Enhancer of Segregation Distorter http://flybase.net/reports/FBgn0000589.html gene E(Sd) 16-Dec-15 2015_12 FBgn0040602 CG14545 http://flybase.net/reports/FBgn0040602.html FBgn0047089 protein_coding_gene BcDNA:RE55691 CG14545 16-Dec-15 2015_12 viable FBgn0265685 CR44492 http://flybase.net/reports/FBgn0265685.html non_protein_coding_gene CR44492 16-Dec-15 2015_12 FBgn0003379 short-winged short winged http://flybase.net/reports/FBgn0003379.html gene "sh, short wing" 16-Dec-15 2015_12 wing FBgn0003687 Tbp TATA binding protein http://flybase.net/reports/FBgn0003687.html "FBgn0013961, FBtr0071679, FBpp0071596" protein_coding_gene "0008134=transcription factor binding, 0005515=protein binding, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0003677=DNA binding, 0001047=core promoter binding, 0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0001092=TFIIA-class transcription factor binding, 0003682=chromatin binding, 0001129=TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly" "0042797=tRNA transcription from RNA polymerase III promoter, 0042796=snRNA transcription from RNA polymerase III promoter, 0060962=regulation of ribosomal protein gene transcription from RNA polymerase II promoter, 0006359=regulation of transcription from RNA polymerase III promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005669=transcription factor TFIID complex, 0005666=DNA-directed RNA polymerase III complex, 0000126=transcription factor TFIIIB complex" "TBP, dTFIID, dtbp, dTbp, CG9874, TFIID, TATA-binding protein, RBP, 42kDa polypeptide, TBP38, TFIIDtau, TfIID, TATA-box binding protein, dTBP, TATA box binding protein, TATA-Binding Protein, TATA box-binding protein" "IPR030491=TATA-box binding protein, conserved site, IPR000814=TATA-box binding protein, IPR012295=Beta2-adaptin/TBP, C-terminal domain" CG9874 16-Dec-15 2015_12 "ENSDARG00000014994(tbp),ENSDARG00000035547(tbpl2)" YER148W(SPT15) WBGene00006542(tbp-1) "ENSXETG00000008556(tbp),ENSXETG00000015710(TEgg129i22.1)" ENSMUSG00000014767(Tbp) ENSG00000112592(TBP) embryonic stage "lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" DRSC23111 K -0.84123306 1.361228404 0.100177131 1.249869573 1.202017971 4.542892511 FBgn0259935 CG42458 http://flybase.net/reports/FBgn0259935.html "FBgn0053277, FBgn0035784, FBgn0053279" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0046872=metal ion binding" "cg18656, CG33277, CG33279, unnamed, CG18656" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG42458 16-Dec-15 2015_12 YPL190C(NAB3) WBGene00020399(ztf-4) FBgn0028955 CG8788 http://flybase.net/reports/FBgn0028955.html FBgn0033384 protein_coding_gene "BEST:HL05962, n(2)k04512" CG8788 16-Dec-15 2015_12 "viable,fertile,visible" eye FBgn0267674 CR46010 http://flybase.net/reports/FBgn0267674.html non_protein_coding_gene CR46010 16-Dec-15 2015_12 FBgn0035677 CG13293 http://flybase.net/reports/FBgn0035677.html protein_coding_gene 0003714=transcription corepressor activity "0006351=transcription, DNA-templated" "IPR016607=Protein SCAI, metazoan/viridiplantae, IPR022709=Protein SCAI" CG13293 16-Dec-15 2015_12 ENSDARG00000060865(LOC556383) ENSXETG00000016827(C9orf126) ENSMUSG00000035236(Scai) ENSG00000173611(SCAI) viable FBgn0267797 CR46122 http://flybase.net/reports/FBgn0267797.html non_protein_coding_gene CR46122 16-Dec-15 2015_12 FBgn0032946 nrv3 nervana 3 http://flybase.net/reports/FBgn0032946.html protein_coding_gene 0005391=sodium:potassium-exchanging ATPase activity "0007605=sensory perception of sound, 0010996=response to auditory stimulus, 0006814=sodium ion transport, 0006813=potassium ion transport" "0005886=plasma membrane, 0005890=sodium:potassium-exchanging ATPase complex" "JYbeta1, nervana3, Nervana 3, Na,K-ATPase beta-subunit, CG8663, Nrv3" IPR000402=Sodium/potassium-transporting ATPase subunit beta CG8663 16-Dec-15 2015_12 "ENSDARG00000013144(atp1b1a),ENSDARG00000015790(atp1b3a),ENSDARG00000037678(LOC100329243),ENSDARG00000042837(atp1b3b),ENSDARG00000013605(atp1b2a),ENSDARG00000034424(atp1b2b),ENSDARG00000053262(atp1b4)" "WBGene00010117(nkb-3),WBGene00007646(nkb-1)" "ENSXETG00000002414(atp1b1),ENSXETG00000004477(ATP1B4),ENSXETG00000025056(atp1b2)" "ENSMUSG00000026576(Atp1b1),ENSMUSG00000041329(Atp1b2),ENSMUSG00000016327(Atp1b4)" "ENSG00000143153(ATP1B1),ENSG00000129244(ATP1B2),ENSG00000101892(ATP1B4),ENSG00000069849(ATP1B3)" "neurophysiology defective,conditional,stress response defective,lethal,viable,auditory perception defective,long lived,starvation stress response defective,male limited,temperature response defective" "mitochondrion,mitochondrion | conditional" FBgn0039462 CG14252 http://flybase.net/reports/FBgn0039462.html protein_coding_gene IPR026095=Myb/SANT-like DNA-binding domain-containing protein CG14252 16-Dec-15 2015_12 viable FBgn0038455 CG14907 http://flybase.net/reports/FBgn0038455.html protein_coding_gene CG14907 16-Dec-15 2015_12 DRSC15027 I 1.764272474 -0.543241323 0.342964934 0.020909302 0.340427147 0.343910865 FBgn0030853 ND-24 NADH dehydrogenase (ubiquinone) 24 kDa subunit http://flybase.net/reports/FBgn0030853.html FBgn0046242 protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "NADH-ubiquinone oxidoreductase 24 kDa subunit, COMPLEX I: 24 kDa subunit, BEST:LP01573, NADH:ubiquinone oxidoreductase 24 kDa subunit, NADH ubiquinone oxidoreductase 24 kDa, CG5703, CG 5703, NUHM" "IPR012336=Thioredoxin-like fold, IPR002023=NADH-quinone oxidoreductase subunit E-like" CG5703 16-Dec-15 2015_12 ENSDARG00000013044(zgc:73198) WBGene00009992(F53F4.10) ENSXETG00000004051(ndufv2) ENSMUSG00000024099(Ndufv2) "ENSG00000178127(NDUFV2),ENSG00000188699" "viable,visible" trichogen cell FBgn0015508 lali lali http://flybase.net/reports/FBgn0015508.html gene "0007430=terminal branching, open tracheal system" misguided 16-Dec-15 2015_12 FBgn0266436 CG45066 http://flybase.net/reports/FBgn0266436.html FBgn0035399 protein_coding_gene 0016021=integral component of membrane CG14955 IPR008795=Prominin CG45066 16-Dec-15 2015_12 FBgn0020268 mus115 mus115 http://flybase.net/reports/FBgn0020268.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0005158 l(2)G137 lethal (2) G137 http://flybase.net/reports/FBgn0005158.html gene 16-Dec-15 2015_12 lethal FBgn0052083 CG32083 http://flybase.net/reports/FBgn0052083.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262651 l(2)47A9-6 lethal (2) 47A9-6 http://flybase.net/reports/FBgn0262651.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082349 HM400 HM400 http://flybase.net/reports/FBgn0082349.html gene 16-Dec-15 2015_12 FBgn0038919 CG17843 http://flybase.net/reports/FBgn0038919.html FBgn0044562 protein_coding_gene "0016491=oxidoreductase activity, 0016971=flavin-linked sulfhydryl oxidase activity" "0032504=multicellular organism reproduction, 0055114=oxidation-reduction process, 0045454=cell redox homeostasis" 0005615=extracellular space "Erv1, DmQSOX2, anon-WO0140519.66" "IPR017905=ERV/ALR sulfhydryl oxidase domain, IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG17843 16-Dec-15 2015_12 ENSDARG00000039459(si:dkey-39n1.2) WBGene00018533(F47B7.2) "ENSXETG00000023156(qscn6),ENSXETG00000000729(QSOX2)" "ENSMUSG00000033684(Qsox1),ENSMUSG00000036327(Qsox2)" "ENSG00000165661(QSOX2),ENSG00000116260(QSOX1)" FBgn0002505 l(3)SG66 lethal (3) SG66 http://flybase.net/reports/FBgn0002505.html FBgn0004731 gene "l(3)ds-3, l(3)g60A, l(3)ds3, l(3)g60R, G60A, B3, l(3)B3" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0035582 CG13705 http://flybase.net/reports/FBgn0035582.html protein_coding_gene CG13705-PA "IPR004011=GYR motif, IPR004019=YLP motif" CG13705 16-Dec-15 2015_12 FBgn0051601 CG31601 http://flybase.net/reports/FBgn0051601.html FBan0031601 protein_coding_gene 0046872=metal ion binding "IPR000571=Zinc finger, CCCH-type" CG31601 16-Dec-15 2015_12 viable FBgn0030998 CG14195 http://flybase.net/reports/FBgn0030998.html protein_coding_gene IPR020846=Major facilitator superfamily domain CG14195 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0266319 CR44984 http://flybase.net/reports/FBgn0266319.html non_protein_coding_gene CR44984 16-Dec-15 2015_12 FBgn0039930 CG11077 http://flybase.net/reports/FBgn0039930.html protein_coding_gene "0000002=mitochondrial genome maintenance, 0042592=homeostatic process" "0005778=peroxisomal membrane, 0005743=mitochondrial inner membrane, 0016021=integral component of membrane" IPR007248=Mpv17/PMP22 CG11077 16-Dec-15 2015_12 ENSDARG00000032431(mpv17) WBGene00011826(T18D3.9) ENSG00000115204(MPV17) "viable,fertile" FBgn0001353 l(1)1EFb lethal (1) 1EFb http://flybase.net/reports/FBgn0001353.html gene l(1)BA2 16-Dec-15 2015_12 lethal FBgn0037873 SdhC "Succinate dehydrogenase, subunit C" http://flybase.net/reports/FBgn0037873.html FBgn0062969 protein_coding_gene "0000104=succinate dehydrogenase activity, 0009055=electron carrier activity, 0008177=succinate dehydrogenase (ubiquinone) activity" "0006121=mitochondrial electron transport, succinate to ubiquinone, 0006105=succinate metabolic process, 0006979=response to oxidative stress, 0006099=tricarboxylic acid cycle, 0008340=determination of adult lifespan" "0005749=mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)" "BcDNA:RH04289, succinate dehydrogenase, RH04289p, sdhC, Succinate dehydrogenase Cytochrome B560 subunit, Succinate dehydrogenase cytochrome b560 subunit, SDH, succinate dehydrogenase C, Succinate dehydrogenase C, Succinate dehydrogenase Cytochrome B560, CG6666, C560" "IPR000701=Succinate dehydrogenase/Fumarate reductase, transmembrane subunit, IPR018495=Succinate dehydrogenase, cytochrome b subunit, conserved site, IPR014314=Succinate dehydrogenase, cytochrome b556 subunit" CG6666 16-Dec-15 2015_12 ENSDARG00000038608(sdhc) "YKL141W(SDH3),YMR118C()" WBGene00003225(mev-1) ENSXETG00000002617(sdhc) ENSMUSG00000058076(Sdhc) ENSG00000143252(SDHC) "viable,visible,short lived,drug conditional" trichogen cell FBgn0262165 Z2528 http://flybase.net/reports/FBgn0262165.html gene 16-Dec-15 2015_12 viable photoreceptor cell R7 FBgn0267515 28SrRNA-ë¬:CR45855 28S ribosomal RNA pseudogene:CR45855 http://flybase.net/reports/FBgn0267515.html pseudogene_attribute CR45855 CR45855 16-Dec-15 2015_12 FBgn0023150 Su(mg)3-2 Suppressor of modifier of gypsy 3-2 http://flybase.net/reports/FBgn0023150.html gene 16-Dec-15 2015_12 FBgn0065311 l(2)SH1949 lethal (2) SH1949 http://flybase.net/reports/FBgn0065311.html gene l(2)SH2 1949 16-Dec-15 2015_12 "lethal,recessive" FBgn0086073 snoRNA:Me18S-A1494 http://flybase.net/reports/FBgn0086073.html snoRNA_gene "Me18S-Am1494, CR34702" CR34702 16-Dec-15 2015_12 FBgn0259358 C639.1 http://flybase.net/reports/FBgn0259358.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing margin,chaeta,ectopic" FBgn0266150 CR44856 http://flybase.net/reports/FBgn0266150.html non_protein_coding_gene CR44856 16-Dec-15 2015_12 FBgn0265959 rdgC retinal degeneration C http://flybase.net/reports/FBgn0265959.html "FBgn0004366, FBgn0036960" protein_coding_gene "0005509=calcium ion binding, 0004722=protein serine/threonine phosphatase activity, 0004723=calcium-dependent protein serine/threonine phosphatase activity, 0005516=calmodulin binding" "0016059=deactivation of rhodopsin mediated signaling, 0007601=visual perception, 0006470=protein dephosphorylation, 0019722=calcium-mediated signaling, 0007602=phototransduction, 0043052=thermotaxis, 0045494=photoreceptor cell maintenance" "0005737=cytoplasm, 0005634=nucleus" "RdgC, RdgC 77B, CG6571, RDGC/PP5, CG13814, DmrdgC-77B, RDGC, CG44746" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR011992=EF-hand domain pair, IPR029052=Metallo-dependent phosphatase-like, IPR018247=EF-Hand 1, calcium-binding site, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR000048=IQ motif, EF-hand binding site, IPR002048=EF-hand domain" CG44746 16-Dec-15 2015_12 "ENSDARG00000020191(zgc:171580),ENSDARG00000012724" WBGene00003969(pef-1) ENSXETG00000006754(PPEF1) "ENSMUSG00000062168(Ppef1),ENSMUSG00000029410(Ppef2)" "ENSG00000156194(PPEF2),ENSG00000086717(PPEF1)" adult stage " ocellus

, mushroom body

, retina

" FBgn0000033 AcpJ Accessory gland protein I http://flybase.net/reports/FBgn0000033.html gene AcpI 16-Dec-15 2015_12 FBgn0010068 M(3)54c M(3)54c http://flybase.net/reports/FBgn0010068.html gene 16-Dec-15 2015_12 FBgn0013252 E(var)3-6 E(var)3-6 http://flybase.net/reports/FBgn0013252.html gene E-var(3)6 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0060852 l(3)S048414 lethal (3) S048414 http://flybase.net/reports/FBgn0060852.html gene 0484/14 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0262690 CR43160 http://flybase.net/reports/FBgn0262690.html non_protein_coding_gene CR43160 16-Dec-15 2015_12 FBgn0026879 CG13364 http://flybase.net/reports/FBgn0026879.html "FBgn0027685, FBgn0042219" protein_coding_gene "CG18451, EG:115C2.12, anon-EST:Posey36" IPR015157=Translation machinery associated TMA7 CG13364 16-Dec-15 2015_12 ENSDARG00000071670(zgc:153700) ENSXETG00000024938(TEgg142n01.1) "viable,body color defective" mesothoracic tergum FBgn0028504 CG12182 http://flybase.net/reports/FBgn0028504.html protein_coding_gene BcDNA:GH02340 IPR017986=WD40-repeat-containing domain CG12182 16-Dec-15 2015_12 "visible,lethal,viable" "embryonic/larval brain,trichogen cell" FBgn0021956 l(2)k10217 lethal (2) k10217 http://flybase.net/reports/FBgn0021956.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022319 l(1)B74.4 lethal (1) B74.4 http://flybase.net/reports/FBgn0022319.html gene B74.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0000723 FER FER ortholog (H. sapiens) http://flybase.net/reports/FBgn0000723.html FBgn0022798 protein_coding_gene "0005524=ATP binding, 0005543=phospholipid binding, 0004713=protein tyrosine kinase activity" "0007411=axon guidance, 0018108=peptidyl-tyrosine phosphorylation, 0007391=dorsal closure, 0008594=photoreceptor cell morphogenesis, 0007394=dorsal closure, elongation of leading edge cells, 0006468=protein phosphorylation, 0051017=actin filament bundle assembly, 0046664=dorsal closure, amnioserosa morphology change" "0005912=adherens junction, 0016020=membrane, 0005886=plasma membrane, 0019898=extrinsic component of membrane, 0005737=cytoplasm" "CG8874, FER, dfer, DFER, fps, Dm FPS, Fps oncogene analog, FPS, Fps85D, DmHD-179, DFer, Dfps, HD-179, dfps85D, dfps, fps85D, dfps 85D, fer, dFer, Dfer, Fer" "IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000980=SH2 domain, IPR017441=Protein kinase, ATP binding site, IPR016250=Tyrosine-protein kinase, Fes/Fps type, IPR001060=FCH domain, IPR031160=F-BAR domain" CG8874 16-Dec-15 2015_12 "ENSDARG00000011449,ENSDARG00000012196(fer)" ENSXETG00000015460(FES) "ENSMUSG00000000127(Fert2),ENSMUSG00000053158(Fes)" "ENSG00000151422(FER),ENSG00000182511(FES)" "viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" "ventral midline,dorsal closure embryo,embryonic leading edge cell & actomyosin,embryonic leading edge cell & filopodium,amnioserosa" DRSC12735 I -0.017009542 1.743626174 -0.240289491 0.085946582 0.771491588 -0.716545839 FBgn0041762 centrin centrin http://flybase.net/reports/FBgn0041762.html gene 16-Dec-15 2015_12 FBgn0015860 anon-1Aa anon-1Aa http://flybase.net/reports/FBgn0015860.html gene distal family 16-Dec-15 2015_12 FBgn0035283 CG12024 http://flybase.net/reports/FBgn0035283.html protein_coding_gene "IPR009060=UBA-like, IPR003892=Ubiquitin system component Cue" CG12024 16-Dec-15 2015_12 "ENSDARG00000068716(zgc:153423),ENSDARG00000054748(zgc:162271)" ENSXETG00000008949(CUEDC1) ENSMUSG00000018378(Cuedc1) ENSG00000180891(CUEDC1) viable DRSC08229 I 0.136445136 1.737151494 -0.636549596 0.198226456 0.201711501 1.234143185 FBgn0065871 l(2)SH0256 lethal (2) SH0256 http://flybase.net/reports/FBgn0065871.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028624 l(2)04207a lethal (2) 04207a http://flybase.net/reports/FBgn0028624.html gene l(2)04207 16-Dec-15 2015_12 "lethal,recessive" FBgn0001000 Fs(2)Tek Female sterile (2) Tekele http://flybase.net/reports/FBgn0001000.html gene "Fs(2)Sz10, Tekele, Tek" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant" "embryo,cleavage nucleus" FBgn0053374 5SrRNA:CR33374 5SrRNA:CR33374 http://flybase.net/reports/FBgn0053374.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33374 CR33374 16-Dec-15 2015_12 FBgn0066321 zol zolotistuy http://flybase.net/reports/FBgn0066321.html gene "0008355=olfactory learning, 0007611=learning or memory, 0048149=behavioral response to ethanol" 16-Dec-15 2015_12 "memory defective,chemical sensitive" FBgn0032243 Klp31E Kinesin-like protein at 31E http://flybase.net/reports/FBgn0032243.html protein_coding_gene "0005524=ATP binding, 0003777=microtubule motor activity, 0003774=motor activity, 0008017=microtubule binding" 0007018=microtubule-based movement "0005737=cytoplasm, 0005871=kinesin complex" "DmCG5300, CG5300, KIF 21A, KIF21A/B, DmKlp31E, KLP31E, Kinesin-like protein at 31E, Klp31E, DmKlp31D" "IPR027640=Kinesin-like protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain" CG5300 16-Dec-15 2015_12 ENSDARG00000009733(LOC570502) WBGene00002223(klp-12) "ENSXETG00000015558(KIF21A),ENSXETG00000017099()" "ENSMUSG00000041642(Kif21b),ENSMUSG00000022629(Kif21a)" "ENSG00000139116(KIF21A),ENSG00000116852(KIF21B)" viable FBgn0010226 GstS1 Glutathione S transferase S1 http://flybase.net/reports/FBgn0010226.html "FBgn0010568, FBgn0022031" protein_coding_gene "0004602=glutathione peroxidase activity, 0004364=glutathione transferase activity" "0006749=glutathione metabolic process, 0006979=response to oxidative stress" 0005737=cytoplasm "glutathione-S-transferase (GST) S1, GstS1-1, n(2)06253, GST2, DmGSTS1-1, l(2)k08805, CG8938, lincRNA.330, DmGST2, GST-2, glutathione S-transferase-S1, Glutathione S transferase 2, unnamed, DmGst-2, l(2)04227, GST S1, gsts1, Glutathione S-transferase 2, Est2, glutathione transferase-related protein, DmGST-2, Glutathione S-transferase, S1, Glutathione S-transferase S1, DmGSTS1, gstD2, Glutathione-S-Transferase 2, glutathione S-transferase-2, GSTII, Gst2, glutathione-S-transferase, GST, DmGstS1-1, GSTS1" "IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal" CG8938 16-Dec-15 2015_12 "ENSDARG00000005039(gstp1),ENSDARG00000057338(gstp2),ENSDARG00000042533(gstm3),ENSDARG00000029473(zgc:173994)" WBGene00001759(gst-11) ENSXETG00000019215(BC077016.1) ENSMUSG00000029919(Hpgds) ENSG00000163106(HPGDS) embryonic stage -- adult stage "viable,lethal,recessive,fertile,visible,wild-type,partially lethal - majority live,male sterile" "embryonic/larval hemocyte | third instar larval stage,macrochaeta,wing,eye" FBgn0016979 snRNA:K9 small nuclear RNA K9 http://flybase.net/reports/FBgn0016979.html snRNA_gene K9 16-Dec-15 2015_12 FBgn0001810 l(1)mt lethal (1) mt http://flybase.net/reports/FBgn0001810.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0003365 sesH stress-sensitive H http://flybase.net/reports/FBgn0003365.html gene 16-Dec-15 2015_12 FBgn0001891 l(2)21De lethal (2) 21De http://flybase.net/reports/FBgn0001891.html gene "l(2)neh5, l(2)neh-5" 16-Dec-15 2015_12 lethal FBgn0265203 CR44263 http://flybase.net/reports/FBgn0265203.html non_protein_coding_gene lincRNA.917 CR44263 16-Dec-15 2015_12 FBgn0035166 CG13902 http://flybase.net/reports/FBgn0035166.html protein_coding_gene IPR003347=JmjC domain CG13902 16-Dec-15 2015_12 ENSDARG00000037844(jmjd5) WBGene00007387(C06H2.3) ENSXETG00000021748(JMJD5) ENSMUSG00000030752(Jmjd5) ENSG00000155666(JMJD5) "viable,fertile" FBgn0044390 Scim4 Sensitized chromosome inheritance modifier 4 http://flybase.net/reports/FBgn0044390.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0050352 CG30352 http://flybase.net/reports/FBgn0050352.html protein_coding_gene 16-Dec-15 2015_12 FBgn0012017 tRNA:Y1:22Fb transfer RNA:tyr1:22Fb http://flybase.net/reports/FBgn0012017.html "FBgn0003842, FBgn0012014, FBgn0051986, FBgn0060007" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033410=UAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:tyr1:22Fb, AE002638.trna3-TyrGTA, CR31986, tRNA[Tyr][[1gamma]], tRNA:Y, tRNA:Y:GTA:AE002638-a, chr2L.trna36-TyrGTA, tRNA[Tyr], tRNA-Tyr" CR31986 16-Dec-15 2015_12 FBgn0037987 CG14739 http://flybase.net/reports/FBgn0037987.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process 0005737=cytoplasm "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG14739 16-Dec-15 2015_12 viable FBgn0001989 ND-B17 NADH dehydrogenase (ubiquinone) B17 subunit http://flybase.net/reports/FBgn0001989.html "FBgn0028508, FBgn0064934" protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NB7M, lethal (2) 35Di, BcDNA:GM23292, NADH:ubiquinone oxidoreductase B17 subunit, NADH-ubiquinone oxidoreductase B17 subunit, BG:DS09217.1, NADH ubiquinone oxidoreductase B17, CG13240, l(2)35Di" "IPR019174=NADH dehydrogenase 1, beta subcomplex, subunit 6" CG13240 16-Dec-15 2015_12 WBGene00014086(ZK809.3) "male sterile,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,viable,visible" "wing,trichogen cell" FBgn0005423 l(1)adl12 lethal (1) adl12 http://flybase.net/reports/FBgn0005423.html gene l(1)adl-12 16-Dec-15 2015_12 "short lived,heat sensitive,lethal,partially lethal - majority die" FBgn0051958 CG31958 http://flybase.net/reports/FBgn0051958.html FBgn0031570 protein_coding_gene 0005509=calcium ion binding CG10022 "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG31958 16-Dec-15 2015_12 FBgn0035868 CG7194 http://flybase.net/reports/FBgn0035868.html "FBgn0025703, FBgn0041577" protein_coding_gene "0055070=copper ion homeostasis, 0008406=gonad development" "BEST:CK01174, CK01174, ck00048, BEST:CK00048, unnamed" IPR024810=Mab-21 domain CG7194 16-Dec-15 2015_12 viable FBgn0058354 CR40354 http://flybase.net/reports/FBgn0058354.html FBan0040354 pseudogene_attribute CG40354 CR40354 16-Dec-15 2015_12 FBgn0001823 l(1)tr lethal (1) tracheae ramified http://flybase.net/reports/FBgn0001823.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0051229 CG31229 http://flybase.net/reports/FBgn0051229.html protein_coding_gene "0015266=protein channel activity, 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity" "0006626=protein targeting to mitochondrion, 0045039=protein import into mitochondrial inner membrane" "0005744=mitochondrial inner membrane presequence translocase complex, 0042721=mitochondrial inner membrane protein insertion complex" IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG31229 16-Dec-15 2015_12 ENSDARG00000069209 YDL217C(TIM22) WBGene00008164(C47G2.3) ENSXETG00000019259(timm22) ENSMUSG00000020843(Timm22) ENSG00000177370(TIMM22) "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0263082 CG43350 http://flybase.net/reports/FBgn0263082.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "lincRNA.88, Chr2L_9349524_9350014.0, CG42845" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG43350 16-Dec-15 2015_12 FBgn0033261 udd under-developed http://flybase.net/reports/FBgn0033261.html protein_coding_gene 1901838=positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter "0005668=RNA polymerase transcription factor SL1 complex, 0005730=nucleolus" "CG18316, Udd, Under-developed" CG18316 16-Dec-15 2015_12 "sterile,recessive,decreased cell number,germline clone,progressive,lethal - all die before end of embryonic stage,viable,visible" "female germline stem cell,germline clone,progressive,trichogen cell" FBgn0030234 CG15211 http://flybase.net/reports/FBgn0030234.html protein_coding_gene 0016020=membrane IPR008253=Marvel domain CG15211 16-Dec-15 2015_12 "ENSDARG00000052020(cmtm4),ENSDARG00000010853(si:dkey-11p23.2)" "ENSXETG00000011233(CMTM4),ENSXETG00000027697(cklfsf6)" "ENSMUSG00000051578(Cmtm4),ENSMUSG00000032434(Cmtm6)" "ENSG00000183723(CMTM4),ENSG00000091317(CMTM6)" viable DRSC19657 I 1.012903768 2.075198594 0.143052709 0.582571327 0.08079973 -0.364468136 FBgn0026749 Yippee Yippee http://flybase.net/reports/FBgn0026749.html "FBtr0073789, FBpp0073620" protein_coding_gene "0008270=zinc ion binding, 0046872=metal ion binding" CG1989 IPR004910=Yippee/Mis18 CG1989 16-Dec-15 2015_12 WBGene00015251(B0546.4) ENSXETG00000007949(ypel5) ENSMUSG00000039770(Ypel5) ENSG00000119801(YPEL5) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0034567 CG15651 http://flybase.net/reports/FBgn0034567.html protein_coding_gene STT CG15651 16-Dec-15 2015_12 ENSDARG00000062451(fkrp) ENSXETG00000018274(FKRP) ENSMUSG00000048920(Fkrp) ENSG00000181027(FKRP) viable FBgn0065645 l(2)SH0752 lethal (2) SH0752 http://flybase.net/reports/FBgn0065645.html gene l(2)SH2 0752 16-Dec-15 2015_12 "lethal,recessive" FBgn0267823 Gmer "GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase" http://flybase.net/reports/FBgn0267823.html "FBgn0034794, FBgn0065314" protein_coding_gene "0050577=GDP-L-fucose synthase activity, 0050662=coenzyme binding, 0042356=GDP-4-dehydro-D-rhamnose reductase activity" "0042351='de novo' GDP-L-fucose biosynthetic process, 0042350=GDP-L-fucose biosynthetic process, 0033227=dsRNA transport" "CG3495, l(2)SH1931, DmGMER, lethal (2) SH1931, GER, GDP-keto-6-deoxymannose 3,5-epimerase/4-reductase, gmer" "IPR028614=GDP-L-fucose synthase, IPR016040=NAD(P)-binding domain, IPR001509=NAD-dependent epimerase/dehydratase, N-terminal domain" CG3495 16-Dec-15 2015_12 "ENSDARG00000039666(tsta3),ENSDARG00000042661(zgc:110348),ENSDARG00000039669(zgc:100864)" WBGene00019813(ger-1) ENSXETG00000010771(TSTA3) ENSMUSG00000022570(Tsta3) ENSG00000104522(TSTA3) FBgn0067885 Mod(Prat:bw)1-2 Mod(Prat:bw)1-2 http://flybase.net/reports/FBgn0067885.html gene Mod-1-2 16-Dec-15 2015_12 FBgn0001705 l(1)ESHS26 lethal (1) ESHS26 http://flybase.net/reports/FBgn0001705.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040701 CG13714 http://flybase.net/reports/FBgn0040701.html protein_coding_gene 16-Dec-15 2015_12 FBgn0022081 l(2)k07526 lethal (2) k07526 http://flybase.net/reports/FBgn0022081.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004946 alarless alarless http://flybase.net/reports/FBgn0004946.html gene alr 16-Dec-15 2015_12 "visible,recessive,viable,good,fertile" "anterior postalar bristle,posterior supraalar bristle,notopleural bristle,humeral bristle,anterior scutellar bristle" FBgn0028141 l(3)S047431b lethal (3) S047431b http://flybase.net/reports/FBgn0028141.html gene "l(3)S047431, 0474/31" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0030338 CG15741 http://flybase.net/reports/FBgn0030338.html protein_coding_gene CG15741 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086691 UK114 UK114 http://flybase.net/reports/FBgn0086691.html "FBgn0028510, FBgn0063211, FBgn0082297" protein_coding_gene 0019239=deaminase activity "0006457=protein folding, 0017148=negative regulation of translation" "DUK114, BG:DS07851.3, CG15261, DUK 114, BcDNA:GM01181" "IPR006056=Enamine/imine deaminase YjgF-like, IPR019897=YjgF-like protein, conserved site, IPR013813=Endoribonuclease L-PSP/chorismate mutase-like, IPR006175=YjgF/YER057c/UK114 family" CG15261 16-Dec-15 2015_12 ENSDARG00000035882(zgc:92739) "YER057C(HMF1),YIL051C(MMF1)" WBGene00016011(C23G10.2) ENSMUSG00000022323(Hrsp12) ENSG00000132541(HRSP12) "partially lethal - majority die,visible" trichogen cell FBgn0034520 lms lateral muscles scarcer http://flybase.net/reports/FBgn0034520.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0060361=flight, 0006355=regulation of transcription, DNA-templated, 0007526=larval somatic muscle development" 0005634=nucleus CG13424 "IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG13424 16-Dec-15 2015_12 "ENSDARG00000021916(vax1),ENSDARG00000058702(vax2)" WBGene00000445(ceh-22) ENSXETG00000003881() "viable,partially lethal - majority die,recessive,visible,flight defective" "A1-7 lateral transverse muscle,wing" FBgn0265826 CR44615 http://flybase.net/reports/FBgn0265826.html non_protein_coding_gene CR44615 16-Dec-15 2015_12 FBgn0033437 CG12926 http://flybase.net/reports/FBgn0033437.html protein_coding_gene "0008431=vitamin E binding, 0005215=transporter activity" 0006810=transport 0005622=intracellular "IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR011074=CRAL/TRIO, N-terminal domain" CG12926 16-Dec-15 2015_12 viable FBgn0069405 Jon99Co Jonah 99Co http://flybase.net/reports/FBgn0069405.html FBgn0001288 gene "JonC, Jon99C, Jonah 99C Beta, Jon99Cbetao" 16-Dec-15 2015_12 FBgn0003271 rol reduced optic lobes http://flybase.net/reports/FBgn0003271.html gene 16-Dec-15 2015_12 "optomotor response defective,neuroanatomy defective,neurophysiology defective,visual behavior defective" "optic lobe,lobula plate,lobula" FBgn0011970 tRNA:S2b:86A transfer RNA:ser2b:86A http://flybase.net/reports/FBgn0011970.html "FBgn0011968, FBgn0011969, FBgn0051396, FBgn0060054" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033446=AGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:ser2b, transfer RNA:ser, tRNA[Ser][[2b]], transfer RNA:ser2b, chr3R.trna62-SerGCT, tRNA[[Ser]], tRNA:S2b, tRNA:S:GCT:AE002708-f, CR31396, tRNA:ser, tRNA:ser2b:86A, tRNA:S, AE002708.trna56-SerGCT" CR31396 16-Dec-15 2015_12 FBgn0083968 CG34132 http://flybase.net/reports/FBgn0083968.html protein_coding_gene IPR004217=Tim10/DDP family zinc finger CG34132 16-Dec-15 2015_12 ENSDARG00000058297(zgc:92895) YGR181W(TIM13) WBGene00006574(tin-13) ENSXETG00000001794(timm13a) ENSMUSG00000020219(Timm13) ENSG00000099800(TIMM13) FBgn0032314 CG7309 http://flybase.net/reports/FBgn0032314.html protein_coding_gene "0015293=symporter activity, 0005310=dicarboxylic acid transmembrane transporter activity, 0008513=secondary active organic cation transmembrane transporter activity, 0015142=tricarboxylic acid transmembrane transporter activity" "0006814=sodium ion transport, 0055085=transmembrane transport" 0016020=membrane IPR001898=Sodium/sulphate symporter CG7309 16-Dec-15 2015_12 viable FBgn0262357 CG43055 http://flybase.net/reports/FBgn0262357.html protein_coding_gene MB8.chr2L.pasa.5 "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin" CG43055 16-Dec-15 2015_12 FBgn0031904 CG5149 http://flybase.net/reports/FBgn0031904.html protein_coding_gene 0005198=structural molecule activity 0005923=bicellular tight junction "IPR017974=Claudin, conserved site, IPR006571=TLDc domain" CG5149 16-Dec-15 2015_12 ENSDARG00000062951(LOC100334320) WBGene00010671(K08E7.1) ENSXETG00000013322(KIAA1609) ENSMUSG00000034105(4632415K11Rik) "viable,fertile" FBgn0000822 fs(1)K1221 female sterile (1) K1221 http://flybase.net/reports/FBgn0000822.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0016998 len leopard http://flybase.net/reports/FBgn0016998.html gene leopard nuclei 16-Dec-15 2015_12 "lethal,recessive,mitotic cell cycle defective" FBgn0003006 Opt Ophthalmoptera http://flybase.net/reports/FBgn0003006.html gene "eyeless-Opthalmoptera, ey[Opt]" 16-Dec-15 2015_12 FBgn0029770 CG4151 http://flybase.net/reports/FBgn0029770.html protein_coding_gene CG4151 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0262182 mir-957 mir-957 stem loop http://flybase.net/reports/FBgn0262182.html miRNA_gene 0046716=muscle cell cellular homeostasis "miR-957, CR42889, dme-mir-957" CR42889 16-Dec-15 2015_12 "viable,lethal,visible" "wing,wing vein,crossvein" FBgn0001124 Got1 Glutamate oxaloacetate transaminase 1 http://flybase.net/reports/FBgn0001124.html "FBgn0034079, FBgn0046303" protein_coding_gene "0030170=pyridoxal phosphate binding, 0004069=L-aspartate:2-oxoglutarate aminotransferase activity" "0006531=aspartate metabolic process, 0006537=glutamate biosynthetic process, 0007476=imaginal disc-derived wing morphogenesis" "0005759=mitochondrial matrix, 0005829=cytosol, 0005777=peroxisome" "Glutamate oxaloacetic transaminase, Got2, BEST:GH07823, GOT-1, CG8430, Got-1, FBgn 1124" "IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR004839=Aminotransferase, class I/classII, IPR000796=Aspartate/other aminotransferase" CG8430 16-Dec-15 2015_12 ENSDARG00000039093(got1) YLR027C(AAT2) WBGene00020146(T01C8.5) ENSXETG00000018428(GOT1) ENSMUSG00000025190(Got1) ENSG00000120053(GOT1) "viable,fertile" FBgn0003952 ung uniungula http://flybase.net/reports/FBgn0003952.html gene 16-Dec-15 2015_12 "visible,recessive" "ommatidium,leg" FBgn0033866 CG6280 http://flybase.net/reports/FBgn0033866.html protein_coding_gene CG6280 16-Dec-15 2015_12 viable FBgn0065237 l(2)SH2164 lethal (2) SH2164 http://flybase.net/reports/FBgn0065237.html gene l(2)SH2 2164 16-Dec-15 2015_12 "lethal,recessive" FBgn0035390 scramb2 scramblase 2 http://flybase.net/reports/FBgn0035390.html protein_coding_gene 0017128=phospholipid scramblase activity "0017121=phospholipid scrambling, 0007268=synaptic transmission" "Scramb2, CG1893, Scramblase" "IPR005552=Scramblase, IPR025659=Tubby C-terminal-like domain" CG1893 16-Dec-15 2015_12 YJR100C(AIM25) "WBGene00011935(scrm-1),WBGene00014200(scrm-2),WBGene00015437(scrm-3)" "viable,visible" trichogen cell FBgn0266234 CR44929 http://flybase.net/reports/FBgn0266234.html non_protein_coding_gene lincRNA.691 CR44929 16-Dec-15 2015_12 FBgn0036396 CG17359 http://flybase.net/reports/FBgn0036396.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG17359 16-Dec-15 2015_12 "ENSXETG00000009496(ZNF362),ENSXETG00000011532(ZNF384)" "ENSG00000128610(FEZF1),ENSG00000153266(FEZF2)" viable FBgn0037758 CG9467 http://flybase.net/reports/FBgn0037758.html protein_coding_gene "0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" "0051260=protein homooligomerization, 0055114=oxidation-reduction process" "IPR011333=POZ domain, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR001680=WD40 repeat, IPR000210=BTB/POZ domain, IPR020830=Glyceraldehyde 3-phosphate dehydrogenase, active site" CG9467 16-Dec-15 2015_12 "ENSDARG00000060854,ENSDARG00000061005(LOC562395)" WBGene00020721(T23B12.6) ENSXETG00000020907(KCTD3) "ENSMUSG00000026608(Kctd3),ENSMUSG00000003759(Shkbp1)" "ENSG00000136636(KCTD3),ENSG00000160410(SHKBP1)" viable FBgn0265088 CR44199 http://flybase.net/reports/FBgn0265088.html non_protein_coding_gene CR44199 16-Dec-15 2015_12 FBgn0001517 l(1)10Fk lethal (1) 10Fk http://flybase.net/reports/FBgn0001517.html gene 16-Dec-15 2015_12 lethal FBgn0260031 22M2 http://flybase.net/reports/FBgn0260031.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0058400 CG40400 http://flybase.net/reports/FBgn0058400.html FBan0040400 protein_coding_gene 16-Dec-15 2015_12 FBgn0024683 l(1)LefEM1 lethal (1) LefEM1 http://flybase.net/reports/FBgn0024683.html gene EM1 16-Dec-15 2015_12 FBgn0015020 Chap31 Chromosome-associated protein 31kD http://flybase.net/reports/FBgn0015020.html gene 0003682=chromatin binding unnamed 16-Dec-15 2015_12 FBgn0027929 NimB1 Nimrod B1 http://flybase.net/reports/FBgn0027929.html FBgn0053119 protein_coding_gene 0042742=defense response to bacterium 0005576=extracellular region "BcDNA:GH07762, CG33119, DS00180.12, nimB1, nim B1, CG8855, NimB1, BG:DS00180.12, nimrod B1, CT25428" "IPR000742=EGF-like domain, IPR009030=Insulin-like growth factor binding protein, N-terminal" CG33119 16-Dec-15 2015_12 "ENSDARG00000038208,ENSDARG00000028168" ENSXETG00000011331(VWDE) viable FBgn0025789 anon-17Ad anon-17Ad http://flybase.net/reports/FBgn0025789.html gene 16-Dec-15 2015_12 FBgn0067066 Nrt::Wnt4 Nrt::Wnt4 http://flybase.net/reports/FBgn0067066.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0040058 CG17417 http://flybase.net/reports/FBgn0040058.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085362 Vml Vitelline membrane-like http://flybase.net/reports/FBgn0085362.html protein_coding_gene 0008316=structural constituent of vitelline membrane "0009950=dorsal/ventral axis specification, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "0035805=egg coat, 0060388=vitelline envelope" "vml, CG34333, CRM-80, vitelline membrane-like" IPR013135=Vitelline membrane cysteine-rich domain CG34333 16-Dec-15 2015_12 FBgn0259829 ifm(2)RS13 indirect flight muscle (2) RS13 http://flybase.net/reports/FBgn0259829.html gene 0007527=adult somatic muscle development 16-Dec-15 2015_12 viable indirect flight muscle FBgn0042206 GstD10 Glutathione S transferase D10 http://flybase.net/reports/FBgn0042206.html FBgn0038019 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "CG18548, gstd10, DmGSTD10, CG17392, GSTD10" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG18548 16-Dec-15 2015_12 YNL229C(URE2) viable FBgn0011955 tRNA:R2:42Aa transfer RNA:arg2:42Aa http://flybase.net/reports/FBgn0011955.html "FBgn0003757, FBgn0011947, FBgn0050317, FBgn0050514, FBgn0060092" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033429=CGU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna93-ArgACG, tRNA[arg], CR30514, tRNA:R:ACG:AE002769-a, DROTG121, tRNA[Arg][[2]], tRNA:arg2:42Aa, AE002769.trna2-ArgACG, CR30317, tRNA:arg1, tRNA[Arg], tRNA:R1, transfer RNA:arg1" CR30514 16-Dec-15 2015_12 FBgn0085794 CR41531 http://flybase.net/reports/FBgn0085794.html FBan0041531 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0265982 CR44761 http://flybase.net/reports/FBgn0265982.html non_protein_coding_gene CR44761 16-Dec-15 2015_12 FBgn0069320 X-167-40 X-167-40 http://flybase.net/reports/FBgn0069320.html gene 16-Dec-15 2015_12 FBgn0086289 GS3087 http://flybase.net/reports/FBgn0086289.html gene 3087 16-Dec-15 2015_12 FBgn0026225 l(1)16Fp lethal (1) 16Fp http://flybase.net/reports/FBgn0026225.html gene ME-VI 16-Dec-15 2015_12 lethal FBgn0085699 CG41572 http://flybase.net/reports/FBgn0085699.html FBan0041572 protein_coding_gene 16-Dec-15 2015_12 FBgn0067057 P72 P72 http://flybase.net/reports/FBgn0067057.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0267097 CR45537 http://flybase.net/reports/FBgn0267097.html non_protein_coding_gene CR45537 16-Dec-15 2015_12 FBgn0036528 CG7579 http://flybase.net/reports/FBgn0036528.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process dppGalNAcT12 "IPR029044=Nucleotide-diphospho-sugar transferases, IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain" CG7579 16-Dec-15 2015_12 viable FBgn0082821 Dar Defender against reaper http://flybase.net/reports/FBgn0082821.html gene 0043069=negative regulation of programmed cell death 16-Dec-15 2015_12 FBgn0266805 CR45267 http://flybase.net/reports/FBgn0266805.html non_protein_coding_gene CR45267 16-Dec-15 2015_12 FBgn0040265 Transpac\pol pol http://flybase.net/reports/FBgn0040265.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0069123 ms(2)Z0738 ms(2)Z0738 http://flybase.net/reports/FBgn0069123.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile primary spermatocyte cyst FBgn0040220 fs(2)BA37 fs(2)BA37 http://flybase.net/reports/FBgn0040220.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0045976 PdL3A PdL3A http://flybase.net/reports/FBgn0045976.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265999 CR44773 http://flybase.net/reports/FBgn0265999.html non_protein_coding_gene CR44773 16-Dec-15 2015_12 FBgn0266790 CR45255 http://flybase.net/reports/FBgn0266790.html non_protein_coding_gene lincRNA.540 CR45255 16-Dec-15 2015_12 FBgn0017621 Eig87F Eig87F http://flybase.net/reports/FBgn0017621.html gene "Eig87, Ecdysone-induced gene 87F" 16-Dec-15 2015_12 FBgn0001351 l(1)1Ef lethal (1) 1Ef http://flybase.net/reports/FBgn0001351.html gene C24 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,maternal effect" "prothoracic segment,maternal effect,anal pad" FBgn0021905 l(2)k12004 lethal (2) k12004 http://flybase.net/reports/FBgn0021905.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034723 CG13506 http://flybase.net/reports/FBgn0034723.html protein_coding_gene "13506, CT32874" "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set" CG13506 16-Dec-15 2015_12 viable FBgn0065098 RNaseMRP:RNA Ribonuclease MRP RNA http://flybase.net/reports/FBgn0065098.html FBgn0053682 non_protein_coding_gene 0006364=rRNA processing "chr3R:19555820..19556089, MRP, small non-messenger RNA 342, CR33682, MRP RNA, RNase MRP RNA, RNase MRP RNA gene, snmRNA:342, snmRNA:342 RNAse MRP, Dm-342, RNAse MRP RNA gene" CR33682 16-Dec-15 2015_12 "developmental rate defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" FBgn0033663 ERp60 ERp60 http://flybase.net/reports/FBgn0033663.html FBgn0025187 protein_coding_gene 0003756=protein disulfide isomerase activity "0006457=protein folding, 0045454=cell redox homeostasis" "0005875=microtubule associated complex, 0005783=endoplasmic reticulum, 0005811=lipid particle, 0012505=endomembrane system" "unnamed, Erp60, D-ERp60, anon-fast-evolving-3D9, Protein disulfide isomerase homolog, Ov6, CG8983, anon-EST:fe3D9" "IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold, IPR005788=Disulphide isomerase, IPR017937=Thioredoxin, conserved site, IPR005792=Protein disulphide isomerase" CG8983 16-Dec-15 2015_12 "ENSDARG00000007354,ENSDARG00000014015(zgc:77086),ENSDARG00000033599(zgc:100906)" "YCL043C(PDI1),YDR518W(EUG1)" WBGene00003964(pdi-3) ENSXETG00000004650(PDIA3) ENSMUSG00000027248(Pdia3) ENSG00000167004(PDIA3) "viable,fertile" FBgn0039161 CG13606 http://flybase.net/reports/FBgn0039161.html protein_coding_gene CG13606 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0262605 CG43131 http://flybase.net/reports/FBgn0262605.html protein_coding_gene CG43131 16-Dec-15 2015_12 FBgn0083086 jaft jaft http://flybase.net/reports/FBgn0083086.html gene "0008101=decapentaplegic signaling pathway, 0007224=smoothened signaling pathway, 0016055=Wnt signaling pathway" "Group C, group C" 16-Dec-15 2015_12 "lethal,recessive" FBgn0032049 Bace beta-site APP-cleaving enzyme http://flybase.net/reports/FBgn0032049.html FBgn0044738 protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis "anon-WO0140519.142, CG13095, dBace, dBACE" "IPR001461=Aspartic peptidase, IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain" CG13095 16-Dec-15 2015_12 "ENSMUSG00000023987(Pgc),ENSMUSG00000004552(Ctse)" "ENSG00000204973,ENSG00000172647,ENSG00000180860,ENSG00000196188(CTSE),ENSG00000096088(PGC)" "lethal,neuroanatomy defective,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,progressive,partially lethal - majority die" "cell body rind of lamina,lamina neuropil,adult brain,subretinal glial cell,adult epithelial glial cell,progressive,lamina" DRSC02197 K 0.878387914 -1.381548336 0.121947144 0.695867782 0.701494532 2.493276147 FBgn0052547 CG32547 http://flybase.net/reports/FBgn0052547.html "FBan0015049, FBan0012610, FBan0015050, FBgn0030922, FBgn0030923, FBgn0030924" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "CG15050, CG15049, CG12610" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG32547 16-Dec-15 2015_12 "viable,fertile" FBgn0003960 urd urdur http://flybase.net/reports/FBgn0003960.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0040773 COX7C Cytochrome c oxidase subunit 7C http://flybase.net/reports/FBgn0040773.html "FBgn0025203, FBgn0063160" protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen, 0007406=negative regulation of neuroblast proliferation" 0005751=mitochondrial respiratory chain complex IV "CoVIIc, Subunit VIIc, Cytochrome c oxidase VIIc, anon-EST:fe3A1, COXO, BcDNA:LD14731, CG2249, Cytochrome c oxidase subunit VIIc, anon-fast-evolving-3A1, unnamed, CoAVIIc, VIIc, Cytochrome c oxidase Polypeptide VIIc, Cytochrome c oxidase polypeptide VIIc" IPR004202=Cytochrome c oxidase subunit VIIc CG2249 16-Dec-15 2015_12 ENSDARG00000053382(cox7c) ENSXETG00000025081(COX7C) "ENSMUSG00000017778(Cox7c),ENSMUSG00000056875(Gm10012)" ENSG00000127184(COX7C) "viable,visible,fertile" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" DRSC06831 E -1.341455284 -0.262917884 -2.180745296 0.121057594 0.451655428 0.893069883 FBgn0028581 mei-217 mei-217 http://flybase.net/reports/FBgn0028581.html "FBgn0053067, FBgn0053935, FBtr0089819, FBpp0088760, FBtr0089820, FBpp0088761, FBtr0089821, FBpp0088762" protein_coding_gene "0007131=reciprocal meiotic recombination, 0007143=female meiotic division" "CG33067, CG33935" CG33935 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female,fertile,recessive,wild-type" meiosis I | female DRSC20349 K 0.865623525 0.665245472 0.623441472 0.246631422 -1.52710277 -0.215843461 FBgn0264357 SNF4Aë_ SNF4/AMP-activated protein kinase gamma subunit http://flybase.net/reports/FBgn0264357.html "FBgn0025803, FBgn0038864, FBgn0043354, FBgn0061867, FBgn0062083, FBgn0063797, FBgn0028227, FBgn0028205" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0019901=protein kinase binding" "0042595=behavioral response to starvation, 0009267=cellular response to starvation, 0045787=positive regulation of cell cycle, 0042632=cholesterol homeostasis, 0030730=sequestering of triglyceride, 0006629=lipid metabolic process, 2001020=regulation of response to DNA damage stimulus, 0006914=autophagy" "0005634=nucleus, 0005737=cytoplasm" "0050/42, l(3)S005042, AMPKgamma, l(3)S012719, EP3015b, AMP-activated protein kinase gamma subunit, FBgn0025803, AMPgamma, loe, CG17299, 0127/19, Snfgamma, lochrig, Snfg, loeI, SNF4Agamma, lethal (3) S005042, lethal (3) S012719, anon-WO0118547.338, CG5806, Lochrig, loechrig, AMPK&ggr, SNF4a, anon-WO0118547.575, anon-WO0257455.21, SNF4Ag, SNF4, snf4, SNF4/AMP-activated protein kinase gamma, SNF4A, SNF4gamma" IPR000644=CBS domain CG17299 16-Dec-15 2015_12 WBGene00013732(Y111B2A.8) "ENSXETG00000009727(PRKAG2),ENSXETG00000011175(PRKAG1)" "ENSMUSG00000028944(Prkag2),ENSMUSG00000067713(Prkag1)" "ENSG00000106617(PRKAG2),ENSG00000181929(PRKAG1)" DRSC13461 EK -0.231549158 0.16235906 -0.657540346 -1.615298176 0.863096522 1.709123044 FBgn0267118 CR45558 http://flybase.net/reports/FBgn0267118.html non_protein_coding_gene CR45558 16-Dec-15 2015_12 FBgn0004389 bnk bottleneck http://flybase.net/reports/FBgn0004389.html protein_coding_gene "0003779=actin binding, 0005547=phosphatidylinositol-3,4,5-trisphosphate binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding" "0007349=cellularization, 0000915=actomyosin contractile ring assembly, 0007015=actin filament organization, 0061024=membrane organization, 0016476=regulation of embryonic cell shape, 0061572=actin filament bundle organization" "0005884=actin filament, 0001725=stress fiber" "CG1480, Bnk" CG1480 16-Dec-15 2015_12 " embryonic stage | cycle 14 , embryonic stage | 2-4 hr " organism

wild-type FBgn0086244 grk::cni http://flybase.net/reports/FBgn0086244.html engineered_fusion_gene Grk-Cni 16-Dec-15 2015_12 FBgn0002978 obt obtuse http://flybase.net/reports/FBgn0002978.html gene 16-Dec-15 2015_12 visible "wing,thorax,eye" FBgn0262121 Lp5 http://flybase.net/reports/FBgn0262121.html gene 16-Dec-15 2015_12 FBgn0037372 CG2091 http://flybase.net/reports/FBgn0037372.html protein_coding_gene 0016787=hydrolase activity "0000290=deadenylation-dependent decapping of nuclear-transcribed mRNA, 0046331=lateral inhibition" "IPR011145=Scavenger mRNA decapping enzyme, N-terminal, IPR008594=Scavenger mRNA decapping enzyme DcpS/DCS2, IPR011146=HIT-like domain" CG2091 16-Dec-15 2015_12 ENSDARG00000009862(dcps) "YOR173W(DCS2),YLR270W(DCS1)" WBGene00000940(dcs-1) ENSXETG00000017917(DCPS) ENSMUSG00000032040(Dcps) ENSG00000110063(DCPS) "viable,visible" "chaeta,supernumerary" FBgn0030890 CG7536 http://flybase.net/reports/FBgn0030890.html protein_coding_gene 0016021=integral component of membrane "IPR004331=SPX domain, IPR004342=EXS, C-terminal" CG7536 16-Dec-15 2015_12 "ENSDARG00000029671(si:dkey-60b12.7),ENSDARG00000062449(si:dkey-6n6.7)" YIL047C(SYG1) WBGene00012659(Y39A1A.22) ENSXETG00000023134(xpr1) ENSMUSG00000026469(Xpr1) ENSG00000143324(XPR1) "viable,fertile" FBgn0040721 CG14350 http://flybase.net/reports/FBgn0040721.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033597 Cpr47Ea Cuticular protein 47Ea http://flybase.net/reports/FBgn0033597.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr47Ea, CG9079" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG9079 16-Dec-15 2015_12 viable FBgn0262829 LA2.1 http://flybase.net/reports/FBgn0262829.html nuclear_gene 0031935=regulation of chromatin silencing Doc 16-Dec-15 2015_12 lethal FBgn0039033 Or94a Odorant receptor 94a http://flybase.net/reports/FBgn0039033.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "94D.1, 94a, DOR108, CG17241" "IPR004117=Olfactory receptor, Drosophila" CG17241 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0035544 CG15021 http://flybase.net/reports/FBgn0035544.html protein_coding_gene CT34875 CG15021 16-Dec-15 2015_12 "viable,fertile" FBgn0032689 CG10413 http://flybase.net/reports/FBgn0032689.html protein_coding_gene 0008511=sodium:potassium:chloride symporter activity "0055085=transmembrane transport, 0006811=ion transport" 0016020=membrane "IPR004841=Amino acid permease/ SLC12A domain, IPR018491=SLC12A transporter, C-terminal" CG10413 16-Dec-15 2015_12 ENSDARG00000060366(slc12a9) YBR235W() WBGene00020207(T04B8.5) ENSXETG00000018392(SLC12A9) ENSMUSG00000037344(Slc12a9) ENSG00000146828(SLC12A9) "viable,partially lethal - majority die,some die during pupal stage" FBgn0267540 CR45880 http://flybase.net/reports/FBgn0267540.html non_protein_coding_gene CR45880 16-Dec-15 2015_12 FBgn0266819 CR45281 http://flybase.net/reports/FBgn0266819.html non_protein_coding_gene lincRNA.S2433 CR45281 16-Dec-15 2015_12 FBgn0038941 CG7080 http://flybase.net/reports/FBgn0038941.html protein_coding_gene CG7080 16-Dec-15 2015_12 viable FBgn0000663 fla flat eye http://flybase.net/reports/FBgn0000663.html gene flateye 16-Dec-15 2015_12 "visible,recessive,viable,good,male,male fertile,female fertile,reduced,female" "wing,eye" FBgn0011087 l(1)Q45 lethal (1) Q45 http://flybase.net/reports/FBgn0011087.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0052329 tRNA:CR32329 transfer RNA:CR32329 http://flybase.net/reports/FBgn0052329.html FBgn0060251 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:E:CTC:AE002584-c, chr3L.trna5-GluCTC, AE002584.trna5-GluCTC, CR32329" CR32329 16-Dec-15 2015_12 FBgn0032979 Clamp Chromatin-linked adaptor for MSL proteins http://flybase.net/reports/FBgn0032979.html FBan0001832 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "CLAMP, CG1832, chromatin-linked adaptor for MSL proteins" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1832 16-Dec-15 2015_12 "YPR015C(),YPR013C()" WBGene00009448(zfp-2) viable DRSC21682 EK -0.951239662 1.467172101 -0.86171823 -1.864013893 -1.115280655 1.552271836 FBgn0263489 CR43604 http://flybase.net/reports/FBgn0263489.html non_protein_coding_gene "unsRNA:d-a, chr2L:8485781..8485873, ncRNA_39" CR43604 16-Dec-15 2015_12 FBgn0005490 l(1)ts2320 lethal (1) ts2320 http://flybase.net/reports/FBgn0005490.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0030510 CG12177 http://flybase.net/reports/FBgn0030510.html protein_coding_gene "IPR001910=Inosine/uridine-preferring nucleoside hydrolase domain, IPR023186=Inosine/uridine-preferring nucleoside hydrolase" CG12177 16-Dec-15 2015_12 "ENSDARG00000042124(si:dkey-4e7.3),ENSDARG00000056203(si:dkey-98p3.7)" YDR400W(URH1) "WBGene00012834(Y43F8C.13),WBGene00017436(F13H8.3)" "ENSXETG00000000637(BC090126.1),ENSXETG00000019416(TGas057p14.1)" viable DRSC19437 I -1.565409413 1.145464011 -0.051409249 0.2078667 0.921473722 -0.597064186 FBgn0034718 wdp windpipe http://flybase.net/reports/FBgn0034718.html FBgn0050504 protein_coding_gene "0060438=trachea development, 0008039=synaptic target recognition" "0016021=integral component of membrane, 0005886=plasma membrane" "CT39092, CG3413, Windpipe, CT11415, connectin-like, CG30504" "IPR001611=Leucine-rich repeat, IPR000483=Cysteine-rich flanking region, C-terminal" CG3413 16-Dec-15 2015_12 viable FBgn0023535 arg arginase http://flybase.net/reports/FBgn0023535.html "FBgn0024982, FBgn0029528" protein_coding_gene "0004053=arginase activity, 0046872=metal ion binding" 0019547=arginine catabolic process to ornithine 0005739=mitochondrion "CG18104, EG:171D11.4, EG:65F1.3" "IPR014033=Arginase, IPR006035=Ureohydrolase, IPR023696=Ureohydrolase domain" CG18104 16-Dec-15 2015_12 "ENSDARG00000071703(si:ch211-146f4.3),ENSDARG00000057429(LOC100148378),ENSDARG00000039269(arg2)" YPL111W(CAR1) WBGene00020658(T21F4.1) "ENSXETG00000008241(arg1),ENSXETG00000007987(ARG2)" "ENSMUSG00000021125(Arg2),ENSMUSG00000019987(Arg1)" "ENSG00000081181(ARG2),ENSG00000118520(ARG1)" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0262169 magu magu http://flybase.net/reports/FBgn0262169.html "FBgn0033478, FBgn0259114" protein_coding_gene "0043395=heparan sulfate proteoglycan binding, 0005509=calcium ion binding" "0044719=regulation of imaginal disc-derived wing size, 0008340=determination of adult lifespan, 0030718=germ-line stem cell maintenance, 0030510=regulation of BMP signaling pathway, 0030513=positive regulation of BMP signaling pathway" "0009897=external side of plasma membrane, 0005578=proteinaceous extracellular matrix, 0005576=extracellular region" "PENT, pent, CT7504, CG2264, pentagone, Pentagone" "IPR018247=EF-Hand 1, calcium-binding site, IPR000716=Thyroglobulin type-1, IPR019577=SPARC/Testican, calcium-binding domain, IPR002350=Kazal domain, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG2264 16-Dec-15 2015_12 ENSDARG00000068430 "ENSMUSG00000023886(Smoc2),ENSMUSG00000021136(Smoc1)" "ENSG00000112562(SMOC2),ENSG00000198732(SMOC1)" FBgn0031937 CG13795 http://flybase.net/reports/FBgn0031937.html protein_coding_gene "0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity" 0006836=neurotransmitter transport 0016021=integral component of membrane CT33284 IPR000175=Sodium:neurotransmitter symporter CG13795 16-Dec-15 2015_12 viable FBgn0053645 CG33645 http://flybase.net/reports/FBgn0053645.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33645 16-Dec-15 2015_12 FBgn0060893 l(3)S044505 lethal (3) S044505 http://flybase.net/reports/FBgn0060893.html gene 0445/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0004734 l(3)85Da lethal (3) 85Da http://flybase.net/reports/FBgn0004734.html gene l(3)85Da-1 16-Dec-15 2015_12 lethal FBgn0267344 l(4)7-M484 lethal (4) 7-M484 http://flybase.net/reports/FBgn0267344.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026428 HDAC6 Histone deacetylase 6 http://flybase.net/reports/FBgn0026428.html protein_coding_gene "0004407=histone deacetylase activity, 0019213=deacetylase activity, 0008270=zinc ion binding" "0007269=neurotransmitter secretion, 0006355=regulation of transcription, DNA-templated, 0022904=respiratory electron transport chain, 0006099=tricarboxylic acid cycle, 0016575=histone deacetylation" 0005737=cytoplasm "hdac6, Histone Deacetylase 6, histone deacetylase HDA2, CG6170, HDAC2, DHDAC2, HDAC, dHDAC6, HDAC6, dHDAC2, DmHDAC2, dmHDA404, histone deacetylase 6" "IPR023801=Histone deacetylase domain, IPR001607=Zinc finger, UBP-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000286=Histone deacetylase superfamily" CG6170 16-Dec-15 2015_12 ENSDARG00000008384(hdac6) WBGene00018319(hdac-6) ENSXETG00000023355(HDAC6) ENSMUSG00000031161(Hdac6) ENSG00000094631(HDAC6) "viable,fertile,lethal" FBgn0260043 33N15 http://flybase.net/reports/FBgn0260043.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0005640 Eip63E Ecdysone-induced protein 63E http://flybase.net/reports/FBgn0005640.html "FBgn0016695, FBgn0024942" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0030332=cyclin binding, 0004672=protein kinase activity, 0020037=heme binding, 0004674=protein serine/threonine kinase activity, 0004693=cyclin-dependent protein serine/threonine kinase activity" "0001700=embryonic development via the syncytial blastoderm, 0002168=instar larval development, 0048589=developmental growth, 0006468=protein phosphorylation, 0007552=metamorphosis, 0002009=morphogenesis of an epithelium" "0005829=cytosol, 0005886=plasma membrane" "EIP63E, Pftaire, L63, CG10579, PFTAIRE, cdc2-63E" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR018506=Cytochrome b5, heme-binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG10579 16-Dec-15 2015_12 ENSDARG00000006093(cdk15) YPL031C(PHO85) WBGene00022519(ZC123.4) ENSXETG00000003466(PFTK1) ENSMUSG00000028926(Cdk14) ENSG00000058091(CDK14) " embryonic stage , embryonic stage -- adult stage " " myoblast

, anterior midgut proper primordium

, tracheal precursor cell

, posterior midgut proper primordium

, embryonic glial cell

, glial cell

, embryonic central nervous system

" "viable,fertile,wild-type,lethal,polyphasic,maternal effect,small body,developmental rate defective,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of larval stage,recessive,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "polytene chromosome,leg,pupa,head,mesothoracic tergum" FBgn0040359 CG11380 http://flybase.net/reports/FBgn0040359.html FBgn0029566 protein_coding_gene EG:BACR42I17.7 CG11380 16-Dec-15 2015_12 viable FBgn0051234 CG31234 http://flybase.net/reports/FBgn0051234.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003750 tri trident http://flybase.net/reports/FBgn0003750.html gene b-l 16-Dec-15 2015_12 "visible,dominant,partially,body color defective,recessive" "trident,scutellum,adult thorax,thorax & cuticle" FBgn0265349 Sfp33A4 Seminal fluid protein 33A4 http://flybase.net/reports/FBgn0265349.html "FBgn0261056, FBgn0066962" protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space anon-SAGE:Wang-036 CG42604 16-Dec-15 2015_12 FBgn0030769 CG13012 http://flybase.net/reports/FBgn0030769.html protein_coding_gene CG13012 16-Dec-15 2015_12 FBgn0041618 SM3-2 SM3-2 http://flybase.net/reports/FBgn0041618.html gene 16-Dec-15 2015_12 FBgn0000450 dic dicephalic http://flybase.net/reports/FBgn0000450.html gene "0030720=oocyte localization involved in germarium-derived egg chamber formation, 0048477=oogenesis, 0007368=determination of left/right symmetry" Dicephalic 16-Dec-15 2015_12 "lethal,maternal effect,semidominant,female sterile" "egg chamber,oocyte,embryonic proventriculus,follicle cell,maternal effect,nurse cell,dorsal appendage,micropyle | maternal effect" FBgn0005099 fs(3)110-8 female sterile (3) 110-8 http://flybase.net/reports/FBgn0005099.html gene 16-Dec-15 2015_12 "female sterile,recessive" endochorion FBgn0010129 l(1)tsG2 lethal (1) tsG2 http://flybase.net/reports/FBgn0010129.html gene 16-Dec-15 2015_12 "lethal,cold sensitive" FBgn0003524 stf stormfront http://flybase.net/reports/FBgn0003524.html gene "0008258=head involution, 0001700=embryonic development via the syncytial blastoderm, 0010004=gastrulation involving germ band extension" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,dorsal closure embryo" FBgn0010028 E(Dl)F25 Enhancer of Delta F25 http://flybase.net/reports/FBgn0010028.html gene 16-Dec-15 2015_12 FBgn0034641 mahj mahjong http://flybase.net/reports/FBgn0034641.html "FBgn0046447, FBgn0062889" protein_coding_gene 0035212=cell competition in a multicellular organism "VprBP, CG10080, anon-WO0172774.151, BcDNA:SD08722, mahj, mahjong" "IPR017986=WD40-repeat-containing domain, IPR016024=Armadillo-type fold, IPR015943=WD40/YVTN repeat-like-containing domain, IPR006594=LIS1 homology motif" CG10080 16-Dec-15 2015_12 WBGene00014243(dcaf-1) ENSXETG00000000071(VPRBP) ENSMUSG00000040325(Vprbp) ENSG00000145041(VPRBP) "developmental rate defective,increased cell death,cell non-autonomous,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal,viable,visible" "wing disc,cell non-autonomous,somatic clone,trichogen cell,tormogen cell" DRSC04053 IK -3.034989139 -0.758681823 -1.22066499 -0.609229107 1.553559547 0.734936356 FBgn0263076 Klp54D Kinesin-like protein at 54D http://flybase.net/reports/FBgn0263076.html "FBgn0004377, FBgn0034241, FBan0015844, FBgn0263028" protein_coding_gene "0005524=ATP binding, 0003777=microtubule motor activity, 0008017=microtubule binding" 0007018=microtubule-based movement 0005871=kinesin complex "CG15844, Klp1, KIF 12, KLP1, CG43323, KIF12, KLP54D, DmKlp54D, Kinesin-like protein 54D" "IPR027640=Kinesin-like protein, IPR028763=Kinesin-like protein KIF12, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain" CG43323 16-Dec-15 2015_12 FBgn0084556 aha angsthase http://flybase.net/reports/FBgn0084556.html gene 0008344=adult locomotory behavior G74 16-Dec-15 2015_12 "locomotor behavior defective,recessive" FBgn0015423 l(1)18DEd lethal (1) 18DEd http://flybase.net/reports/FBgn0015423.html gene l(1)18DEa 16-Dec-15 2015_12 "lethal,recessive" FBgn0058221 CG40221 http://flybase.net/reports/FBgn0058221.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266957 CR45408 http://flybase.net/reports/FBgn0266957.html non_protein_coding_gene CR45408 16-Dec-15 2015_12 FBgn0039846 CG11337 http://flybase.net/reports/FBgn0039846.html protein_coding_gene "0004654=polyribonucleotide nucleotidyltransferase activity, 0003723=RNA binding, 0000175=3'-5'-exoribonuclease activity" "0006396=RNA processing, 0006402=mRNA catabolic process" "IPR004088=K Homology domain, type 1, IPR012162=Polyribonucleotide nucleotidyltransferase, IPR004087=K Homology domain, IPR003029=S1 domain, IPR001247=Exoribonuclease, phosphorolytic domain 1, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR027408=PNPase/RNase PH domain, IPR022967=RNA-binding domain, S1, IPR012340=Nucleic acid-binding, OB-fold, IPR015848=Polyribonucleotide nucleotidyltransferase, RNA-binding domain, IPR015847=Exoribonuclease, phosphorolytic domain 2" CG11337 16-Dec-15 2015_12 WBGene00015266(BE0003N10.1) ENSXETG00000006075(pnpt1) ENSMUSG00000020464(Pnpt1) ENSG00000138035(PNPT1) "viable,fertile" DRSC14304 K -0.418267901 0.093262813 -0.117566202 0.002624117 -1.750292106 -0.551630815 FBgn0266953 CR45404 http://flybase.net/reports/FBgn0266953.html non_protein_coding_gene CR45404 16-Dec-15 2015_12 FBgn0005506 l(2)24EFd lethal (2) 24EFd http://flybase.net/reports/FBgn0005506.html gene l(2)Gr.IV 16-Dec-15 2015_12 "lethal,recessive" FBgn0046327 l(3)S069605b lethal (3) S069605b http://flybase.net/reports/FBgn0046327.html gene "l(3)S079415b, 0696/05" 16-Dec-15 2015_12 "lethal,recessive" FBgn0261831 CG42763 http://flybase.net/reports/FBgn0261831.html protein_coding_gene CG42763 16-Dec-15 2015_12 FBgn0037279 CG1129 http://flybase.net/reports/FBgn0037279.html protein_coding_gene 0004475=mannose-1-phosphate guanylyltransferase activity "0035167=larval lymph gland hemopoiesis, 0009058=biosynthetic process" "IPR018357=Hexapeptide transferase, conserved site, IPR005835=Nucleotidyl transferase domain, IPR029044=Nucleotide-diphospho-sugar transferases, IPR001451=Hexapeptide repeat" CG1129 16-Dec-15 2015_12 ENSDARG00000017658(gmppb) YDL055C(PSA1) WBGene00016583(tag-335) ENSXETG00000005954(gmppb) ENSMUSG00000070284(Gmppb) ENSG00000173540(GMPPB) "neuroanatomy defective,lethal" "mushroom body & axon7B,Kenyon cell,adult mushroom body" FBgn0259140 CG42255 http://flybase.net/reports/FBgn0259140.html "FBgn0052092, FBgn0036209, FBgn0052094" protein_coding_gene "0004872=receptor activity, 0004222=metalloendopeptidase activity, 0005509=calcium ion binding" 0006898=receptor-mediated endocytosis "0005829=cytosol, 0016020=membrane, 0005875=microtubule associated complex" "CG5956, CG32092, CT18701, CG32094" "IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR028876=Cubilin, IPR001881=EGF-like calcium-binding domain, IPR000859=CUB domain, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG42255 16-Dec-15 2015_12 FBgn0000523 dwx dwarfex http://flybase.net/reports/FBgn0000523.html gene 16-Dec-15 2015_12 visible "wing,adult abdomen,adult thorax" FBgn0267103 CR45543 http://flybase.net/reports/FBgn0267103.html non_protein_coding_gene lincRNA.973 CR45543 16-Dec-15 2015_12 FBgn0013713 Abl::Abelson\v-Abl v-Abl http://flybase.net/reports/FBgn0013713.html engineered_fusion_gene 16-Dec-15 2015_12 wild-type FBgn0025875 opus\pol pol http://flybase.net/reports/FBgn0025875.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "yoyo\Pol, ORF2, yoyo\pol, pol" "IPR000477=Reverse transcriptase domain, IPR012337=Ribonuclease H-like domain, IPR001584=Integrase, catalytic core" 16-Dec-15 2015_12 FBgn0263507 CR43496 http://flybase.net/reports/FBgn0263507.html non_protein_coding_gene CR43496 16-Dec-15 2015_12 FBgn0035980 CG4447 http://flybase.net/reports/FBgn0035980.html protein_coding_gene 0006412=translation "IPR024946=Arginine repressor C-terminal-like domain, IPR023584=Ribosome recycling factor domain, IPR002661=Ribosome recycling factor" CG4447 16-Dec-15 2015_12 ENSDARG00000034174(mrrf) WBGene00020625(T20F5.3) ENSXETG00000016327() ENSMUSG00000026887(Mrrf) ENSG00000148187(MRRF) viable FBgn0027163 l(2)KC-C l(2)Karp and Cherbas C http://flybase.net/reports/FBgn0027163.html gene C 16-Dec-15 2015_12 "lethal,recessive" FBgn0014390 su(lz) suppressor of lozenge http://flybase.net/reports/FBgn0014390.html gene 16-Dec-15 2015_12 FBgn0030246 CG1582 http://flybase.net/reports/FBgn0030246.html protein_coding_gene "0004386=helicase activity, 0003676=nucleic acid binding, 0008026=ATP-dependent helicase activity, 0005524=ATP binding, 0046872=metal ion binding" cg1582 "IPR011709=Domain of unknown function DUF1605, IPR000571=Zinc finger, CCCH-type, IPR007502=Helicase-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006575=RWD domain, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG1582 16-Dec-15 2015_12 ENSDARG00000057660(dhx57) YLR419W() ENSMUSG00000035051(Dhx57) ENSG00000163214(DHX57) viable FBgn0034829 CG9899 http://flybase.net/reports/FBgn0034829.html protein_coding_gene "0016570=histone modification, 0006355=regulation of transcription, DNA-templated" 0016593=Cdc73/Paf1 complex "IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1, IPR031101=RNA polymerase-associated protein Ctr9, IPR011990=Tetratricopeptide-like helical domain" CG9899 16-Dec-15 2015_12 YOL145C(CTR9) ENSXETG00000013673(CTR9) FBgn0264408 FCE-A http://flybase.net/reports/FBgn0264408.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0266304 CR44969 http://flybase.net/reports/FBgn0266304.html non_protein_coding_gene CR44969 16-Dec-15 2015_12 FBgn0061471 5.8SrRNA 5.8SrRNA http://flybase.net/reports/FBgn0061471.html rRNA_gene "5.8S DNA and IGS, 5.8SRNA, 5.8S, 5.8S and 2S ribosomal rRNA, 5.8S rRNA" 16-Dec-15 2015_12 FBgn0001485 l(1)10Ae lethal (1) 10Ae http://flybase.net/reports/FBgn0001485.html gene "l(1)BP7, L8, l(1)G10, 8, l(1)L8, l(1)8" 16-Dec-15 2015_12 "some die during larval stage,lethal,recessive,partially lethal - majority die,heat sensitive,lethal - all die before end of larval stage,cold sensitive,dominant" FBgn0037841 CG4565 http://flybase.net/reports/FBgn0037841.html protein_coding_gene "0018024=histone-lysine N-methyltransferase activity, 0008270=zinc ion binding" 0034968=histone lysine methylation 0005634=nucleus "IPR001214=SET domain, IPR007728=Pre-SET domain, IPR003616=Post-SET domain" CG4565 16-Dec-15 2015_12 ENSDARG00000057968 WBGene00021515(set-23) ENSMUSG00000034639(Setmar) "viable,fertile" FBgn0058156 CG40156 http://flybase.net/reports/FBgn0058156.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029843 Nep1 Neprilysin 1 http://flybase.net/reports/FBgn0029843.html "FBgn0029841, FBgn0029842" protein_coding_gene "0004222=metalloendopeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis 0016021=integral component of membrane "CG5905, CG5894, CG5914, NEP, nep1, dNEP1, NEP1, DmeNEP1" "IPR000718=Peptidase M13, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR008753=Peptidase M13, N-terminal domain" CG5905 16-Dec-15 2015_12 ENSDARG00000026398(LOC560703) WBGene00020230(nep-2) "ENSG00000142606(MMEL1),ENSG00000196549(MME)" "visible,lethal,viable" wing FBgn0065754 l(2)SH0490 lethal (2) SH0490 http://flybase.net/reports/FBgn0065754.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262359 CG43057 http://flybase.net/reports/FBgn0262359.html protein_coding_gene CG43057 16-Dec-15 2015_12 FBgn0005004 dcm dark carmine http://flybase.net/reports/FBgn0005004.html gene d-cm 16-Dec-15 2015_12 "eye color defective,recessive" pigment cell FBgn0028015 l(3)S106605 lethal (3) S106605 http://flybase.net/reports/FBgn0028015.html gene 1066/05 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0002348 l(3)87Cd lethal (3) 87Cd http://flybase.net/reports/FBgn0002348.html gene "l(3)SzD, l(3)m114-SzD" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,partially lethal - majority die" FBgn0029119 Su(Sxlfs)X2 Su(Sxlfs)X2 http://flybase.net/reports/FBgn0029119.html gene 16-Dec-15 2015_12 FBgn0036206 CG5964 http://flybase.net/reports/FBgn0036206.html protein_coding_gene CG5964 16-Dec-15 2015_12 ENSMUSG00000020776(Fbf1) "partially lethal - majority die,some die during pupal stage" FBgn0011061 l(1)Q14 lethal (1) Q14 http://flybase.net/reports/FBgn0011061.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0264449 CG43867 http://flybase.net/reports/FBgn0264449.html "FBgn0259100, FBgn0025623, FBgn0029537, FBgn0025622, FBgn0029538" protein_coding_gene 0005856=cytoskeleton "EG:34F3.1, CG42248, EG:34F3.2, CG12467, CG14632, CG14633" "IPR001849=Pleckstrin homology domain, IPR000299=FERM domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749=Band 4.1 domain, IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000857=MyTH4 domain, IPR029071=Ubiquitin-related domain" CG43867 16-Dec-15 2015_12 ENSDARG00000053835(plekhh1) WBGene00003143(max-1) ENSXETG00000009282(PLEKHH2) "ENSMUSG00000040852(Plekhh2),ENSMUSG00000060716(Plekhh1)" "ENSG00000152527(PLEKHH2),ENSG00000054690(PLEKHH1)" FBgn0023087 en::h en::h http://flybase.net/reports/FBgn0023087.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,female" FBgn0051832 CG31832 http://flybase.net/reports/FBgn0051832.html FBgn0028923 protein_coding_gene "BG:DS00929.7, DS00929.7, Fibrinogen-related protein, FBpp0080285, AAF44911" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR020837=Fibrinogen, conserved site, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG31832 16-Dec-15 2015_12 WBGene00017013(D1009.3) FBgn0259856 Su(Ste):CR42425 Su(Ste):CR42425 http://flybase.net/reports/FBgn0259856.html non_protein_coding_gene CR42425 CR42425 16-Dec-15 2015_12 FBgn0000944 fs(2)A14 female sterile (2) A14 http://flybase.net/reports/FBgn0000944.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect,mitotic cell cycle defective" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0016785 anon-98EFa anon-98EFa http://flybase.net/reports/FBgn0016785.html gene unnamed 16-Dec-15 2015_12 FBgn0027532 CG7139 http://flybase.net/reports/FBgn0027532.html FBgn0062025 protein_coding_gene "mdcds_30855, BcDNA:LD21293, anon-WO0118547.415" "IPR002625=Smr domain, IPR013899=Domain of unknown function DUF1771, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG7139 16-Dec-15 2015_12 ENSDARG00000061451(n4bp2) WBGene00017811(F26A1.13) ENSMUSG00000037795(N4bp2) ENSG00000078177(N4BP2) viable FBgn0002287 l(3)73Bc lethal (3) 73Bc http://flybase.net/reports/FBgn0002287.html gene l(3)std5 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0038435 Gyc-89Da Guanylyl cyclase at 89Da http://flybase.net/reports/FBgn0038435.html protein_coding_gene "0046982=protein heterodimerization activity, 0020037=heme binding, 0004383=guanylate cyclase activity" "0000302=response to reactive oxygen species, 0035556=intracellular signal transduction, 0001666=response to hypoxia, 0006182=cGMP biosynthetic process" "0008074=guanylate cyclase complex, soluble" "GYCb, CG14885" "IPR011644=Heme-NO binding, IPR011645=Haem NO binding associated, IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR024096=NO signalling/Golgi transport ligand-binding domain, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG14885 16-Dec-15 2015_12 "stress response defective,viable,fertile,taste perception defective" FBgn0039241 CG11089 http://flybase.net/reports/FBgn0039241.html FBgn0043823 protein_coding_gene "0004643=phosphoribosylaminoimidazolecarboxamide formyltransferase activity, 0003937=IMP cyclohydrolase activity" "0006164=purine nucleotide biosynthetic process, 0042060=wound healing" "CT30991, BEST:GH11240, 153761_at, atic" "IPR016193=Cytidine deaminase-like, IPR024050=AICAR transformylase, insert domain, IPR002695=AICARFT/IMPCHase bienzyme, IPR024051=AICAR transformylase domain, IPR011607=Methylglyoxal synthase-like domain" CG11089 16-Dec-15 2015_12 ENSDARG00000016706(atic) "YMR120C(ADE17),YLR028C(ADE16)" WBGene00016957(C55F2.1) ENSXETG00000025087(atic) ENSMUSG00000026192(Atic) ENSG00000138363(ATIC) viable FBgn0028063 l(3)S092416 lethal (3) S092416 http://flybase.net/reports/FBgn0028063.html gene 0924/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0264830 CG44038 http://flybase.net/reports/FBgn0264830.html protein_coding_gene CG44038 16-Dec-15 2015_12 FBgn0263569 mir-4968 mir-4968 stem loop http://flybase.net/reports/FBgn0263569.html miRNA_gene "CR43554, dme-mir-4968" CR43554 16-Dec-15 2015_12 viable FBgn0031516 CG9663 http://flybase.net/reports/FBgn0031516.html protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" 0043190=ATP-binding cassette (ABC) transporter complex "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR013525=ABC-2 type transporter" CG9663 16-Dec-15 2015_12 "viable,fertile" FBgn0011897 tRNA:K2:56EF transfer RNA:lys2:56EF http://flybase.net/reports/FBgn0011897.html "FBgn0011886, FBgn0050520, FBgn0060178" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033444=AAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30520, chr2R.trna40-LysCTT, AE002787.trna56-LysCTT, tRNA[Lys][[2]], tRNA:K2, tRNA:lys2:56EF, tRNA:K:CTT:AE002787-b" CR30520 16-Dec-15 2015_12 FBgn0086908 egg eggless http://flybase.net/reports/FBgn0086908.html "FBgn0065010, FBgn0050422, FBgn0035061, FBgn0050426" protein_coding_gene "0010385=double-stranded methylated DNA binding, 0046974=histone methyltransferase activity (H3-K9 specific), 0005515=protein binding, 0008270=zinc ion binding" "0040029=regulation of gene expression, epigenetic, 0048477=oogenesis, 0051567=histone H3-K9 methylation, 0045892=negative regulation of transcription, DNA-templated, 0035220=wing disc development, 0060968=regulation of gene silencing, 0002165=instar larval or pupal development, 0048132=female germ-line stem cell asymmetric division, 0016571=histone methylation, 0045814=negative regulation of gene expression, epigenetic, 0044026=DNA hypermethylation" "0005700=polytene chromosome, 0005634=nucleus, 0005737=cytoplasm, 0010369=chromocenter" "AAM70794, CG30426, DmSetdb1, BcDNA:AT13877, Egg, dSETDB1, Setdb1, dEset, SETDB1, CG12196, Dmsetdb1, CG30422, AAF47268 Dm, Histone-lysine N-methyltransferase, Eggless, SetDB1, dsetdb1, dSetdb1, Dm-setdb1, EGG" "IPR016177=DNA-binding domain, IPR003616=Post-SET domain, IPR007728=Pre-SET domain, IPR001739=Methyl-CpG DNA binding, IPR001214=SET domain" CG12196 16-Dec-15 2015_12 "ENSDARG00000061724(setdb1b),ENSDARG00000041243(setdb1a)" WBGene00019883(met-2) ENSXETG00000008936(SETDB1) ENSMUSG00000015697(Setdb1) ENSG00000143379(SETDB1) DRSC22534 I 1.917147673 1.450678183 -0.401585128 1.390188247 -0.052668166 -0.116368872 FBgn0065193 l(2)SH2326 lethal (2) SH2326 http://flybase.net/reports/FBgn0065193.html gene l(2)SH2 2326 16-Dec-15 2015_12 "lethal,recessive" FBgn0051897 CG31897 http://flybase.net/reports/FBgn0051897.html FBgn0045132 protein_coding_gene NEST:bs30d08 CG31897 16-Dec-15 2015_12 viable FBgn0022751 anon-B3 anon-B3 http://flybase.net/reports/FBgn0022751.html gene B3 16-Dec-15 2015_12 FBgn0043533 Obp56f Odorant-binding protein 56f http://flybase.net/reports/FBgn0043533.html "FBgn0050450, FBgn0063477" protein_coding_gene 0005549=odorant binding "0007606=sensory perception of chemical stimulus, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "anon-AE003794.1, CG30450, DmelObp56f, Obp-d, unnamed, 56f" IPR006170=Pheromone/general odorant binding protein CG30450 16-Dec-15 2015_12 viable DRSC22270 I -0.8604428 -2.877549169 -0.176850827 0.427165702 0.289168331 -0.397774086 FBgn0266166 CR44872 http://flybase.net/reports/FBgn0266166.html non_protein_coding_gene CR44872 16-Dec-15 2015_12 FBgn0026396 Or22c Odorant receptor 22c http://flybase.net/reports/FBgn0026396.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "CG15377, Or22C.1, 22C.1, 22c, DOR16, Olfactory receptor 22C.1, DOR22C.1" "IPR004117=Olfactory receptor, Drosophila" CG15377 16-Dec-15 2015_12 smell perception defective FBgn0266549 CR45102 http://flybase.net/reports/FBgn0266549.html non_protein_coding_gene RE64691 CR45102 16-Dec-15 2015_12 FBgn0266009 CR44782 http://flybase.net/reports/FBgn0266009.html non_protein_coding_gene lincRNA.380 CR44782 16-Dec-15 2015_12 FBgn0038842 hdly hadley http://flybase.net/reports/FBgn0038842.html protein_coding_gene "0045434=negative regulation of female receptivity, post-mating" CG5630 CG5630 16-Dec-15 2015_12 "mating behavior defective,female limited,female semi-fertile" FBgn0034924 CG17658 http://flybase.net/reports/FBgn0034924.html protein_coding_gene "IPR002893=Zinc finger, MYND-type" CG17658 16-Dec-15 2015_12 viable FBgn0040996 CG12617 http://flybase.net/reports/FBgn0040996.html protein_coding_gene 38C.31 CG12617 16-Dec-15 2015_12 viable FBgn0003014 osh outshifted http://flybase.net/reports/FBgn0003014.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive,eye color defective,body color defective" "wing,eye" FBgn0267944 CR46224 http://flybase.net/reports/FBgn0267944.html non_protein_coding_gene lincRNA.705 CR46224 16-Dec-15 2015_12 FBgn0052939 CG32939 http://flybase.net/reports/FBgn0052939.html protein_coding_gene IPR016181=Acyl-CoA N-acyltransferase CG32939 16-Dec-15 2015_12 FBgn0266975 CR45426 http://flybase.net/reports/FBgn0266975.html non_protein_coding_gene CR45426 16-Dec-15 2015_12 FBgn0003945 Udg Uracil DNA glycosylase http://flybase.net/reports/FBgn0003945.html gene 0004844=uracil DNA N-glycosylase activity UDG 16-Dec-15 2015_12 FBgn0037601 Cyp313b1 Cyp313b1 http://flybase.net/reports/FBgn0037601.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "313b1, CG9716" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG9716 16-Dec-15 2015_12 YDR402C(DIT2) viable FBgn0262282 mir-984 mir-984 stem loop http://flybase.net/reports/FBgn0262282.html miRNA_gene "CR42989, dme-mir-984, miR-984" CR42989 16-Dec-15 2015_12 "viable,lethal,visible,lethal - all die before end of larval stage,some die during larval stage" wing FBgn0037643 skap skpA associated protein http://flybase.net/reports/FBgn0037643.html protein_coding_gene "0004775=succinate-CoA ligase (ADP-forming) activity, 0005524=ATP binding, 0046872=metal ion binding" "0010824=regulation of centrosome duplication, 0006099=tricarboxylic acid cycle, 0007052=mitotic spindle organization" "0005875=microtubule associated complex, 0009361=succinate-CoA ligase complex (ADP-forming), 0005813=centrosome, 0005739=mitochondrion" "SkpA Associated Protein, Skap, CG11963, CGI 1963, SkAP" "IPR016102=Succinyl-CoA synthetase-like, IPR005811=ATP-citrate lyase/succinyl-CoA ligase, IPR005809=Succinyl-CoA synthetase, beta subunit, IPR017866=Succinyl-CoA synthetase, beta subunit, conserved site, IPR011761=ATP-grasp fold, IPR013816=ATP-grasp fold, subdomain 2, IPR013650=ATP-grasp fold, succinyl-CoA synthetase-type, IPR013815=ATP-grasp fold, subdomain 1" CG11963 16-Dec-15 2015_12 ENSDARG00000005359(sucla2) YGR244C(LSC2) WBGene00009812(F47B10.1) ENSXETG00000000548(scs-beta) ENSMUSG00000022110(Sucla2) ENSG00000136143(SUCLA2) "partially lethal - majority die,viable" FBgn0000839 fs(1)M26 female sterile (1) M26 http://flybase.net/reports/FBgn0000839.html gene 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0015298 Srp19 Signal recognition particle protein 19 http://flybase.net/reports/FBgn0015298.html protein_coding_gene 0008312=7S RNA binding 0006614=SRP-dependent cotranslational protein targeting to membrane "0005786=signal recognition particle, endoplasmic reticulum targeting" "SRP19, CG4457, srp19, Signal recognition particle 19 kD protein" "IPR002778=Signal recognition particle, SRP19 subunit" CG4457 16-Dec-15 2015_12 ENSDARG00000035699(srp19) WBGene00018159(F37F2.2) ENSXETG00000011993(srp19) ENSMUSG00000014504(Srp19) ENSG00000153037(SRP19) embryonic stage -- adult stage FBgn0053454 CG33454 http://flybase.net/reports/FBgn0053454.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33454 16-Dec-15 2015_12 FBgn0266700 CR45190 http://flybase.net/reports/FBgn0266700.html non_protein_coding_gene CR45190 16-Dec-15 2015_12 FBgn0023180 Orc6 Origin recognition complex subunit 6 http://flybase.net/reports/FBgn0023180.html protein_coding_gene "0005096=GTPase activator activity, 0042803=protein homodimerization activity, 0003677=DNA binding" "0006260=DNA replication, 0007067=mitotic nuclear division, 0006270=DNA replication initiation, 0043547=positive regulation of GTPase activity, 0006342=chromatin silencing, 0032185=septin cytoskeleton organization, 0006261=DNA-dependent DNA replication" "0005664=nuclear origin of replication recognition complex, 0031105=septin complex, 0000808=origin recognition complex, 0005886=plasma membrane, 0032156=septin cytoskeleton" "orc6, ORC, DmORC6, CG1584, DmORC 6, ORC6, rDmORC" "IPR008721=Origin recognition complex, subunit 6, IPR020529=Origin recognition complex, subunit 6, metazoa/plant" CG1584 16-Dec-15 2015_12 ENSDARG00000014447(orc6l) ENSXETG00000003891(orc6l) ENSMUSG00000031697(Orc6l) ENSG00000091651(ORC6) " embryonic stage , embryonic stage&&larval stage " "neuroanatomy defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during third instar larval stage,increased cell death,lethal,viable,visible" "embryonic/larval optic lobe,imaginal disc,presumptive embryonic salivary gland,embryonic/larval brain,trichogen cell" DRSC07497 I 1.734801406 -0.126049285 -0.374049829 0.284810577 -0.257553232 -0.785302697 FBgn0011963 tRNA:R2:84Fe transfer RNA:arg2:84Fe http://flybase.net/reports/FBgn0011963.html "FBgn0003758, FBgn0011947, FBgn0051584, FBgn0060093" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033429=CGU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:R:ACG:AE002708-e, transfer RNA:arg1, tRNA:R1, tRNA:arg1, tRNA[arg], chr3R.trna72-ArgACG, AE002708.trna66-ArgACG, tRNA:arg2:84Fe, tRNA[Arg][[2]], CR31584" CR31584 16-Dec-15 2015_12 FBgn0024682 l(1)LefEM2 lethal (1) LefEM2 http://flybase.net/reports/FBgn0024682.html gene EM2 16-Dec-15 2015_12 FBgn0013691 mt:tRNA:D mitochondrial aspartic acid tRNA http://flybase.net/reports/FBgn0013691.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006300, CR34071" CR34071 16-Dec-15 2015_12 FBgn0037657 hyx hyrax http://flybase.net/reports/FBgn0037657.html protein_coding_gene 0008134=transcription factor binding "0007480=imaginal disc-derived leg morphogenesis, 0016570=histone modification, 0016055=Wnt signaling pathway, 0008586=imaginal disc-derived wing vein morphogenesis, 0006368=transcription elongation from RNA polymerase II promoter, 0045893=positive regulation of transcription, DNA-templated, 0045880=positive regulation of smoothened signaling pathway, 0008587=imaginal disc-derived wing margin morphogenesis, 0001745=compound eye morphogenesis, 0008407=chaeta morphogenesis" "0005634=nucleus, 0043234=protein complex, 0016593=Cdc73/Paf1 complex" "Cdc73, Hyx, Hyrax, CG11990, hyx/CDC73, Parafibromin" "IPR007852=Cdc73/Parafibromin, IPR031336=Cell division control protein 73, C-terminal" CG11990 16-Dec-15 2015_12 ENSDARG00000020201(cdc73) WBGene00018064(F35F11.1) ENSXETG00000004533(hrpt2) ENSMUSG00000026361(Cdc73) ENSG00000134371(CDC73) "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,cell lethalcell lethal,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal" "wing,leg,wing margin,somatic clone,wing vein,macrochaeta,eye" DRSC14462 IEK 3.942875649 2.937888866 2.482426048 0.62218994 2.159218666 1.016008489 FBgn0020568 anon-88Ab anon-88Ab http://flybase.net/reports/FBgn0020568.html gene unnamed 16-Dec-15 2015_12 FBgn0010117 l(1)1 lethal (1) 1 http://flybase.net/reports/FBgn0010117.html gene 16-Dec-15 2015_12 lethal FBgn0002445 l(3)S2 lethal (3) S2 http://flybase.net/reports/FBgn0002445.html gene 16-Dec-15 2015_12 lethal FBgn0259442 C923 http://flybase.net/reports/FBgn0259442.html gene 16-Dec-15 2015_12 "visible,lethal" "wing,chaeta,ectopic" FBgn0029727 CG6978 http://flybase.net/reports/FBgn0029727.html protein_coding_gene 0005436=sodium:phosphate symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG6978 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" viable FBgn0029596 CG14054 http://flybase.net/reports/FBgn0029596.html FBgn0061456 protein_coding_gene BcDNA:AT13882 CG14054 16-Dec-15 2015_12 "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0000845 fs(1)M32 female sterile (1) M32 http://flybase.net/reports/FBgn0000845.html gene 16-Dec-15 2015_12 "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,cold sensitive,some die during embryonic stage" egg FBgn0033188 Drat Death resistor Adh domain containing target http://flybase.net/reports/FBgn0033188.html protein_coding_gene "0016491=oxidoreductase activity, 0008270=zinc ion binding" "0055114=oxidation-reduction process, 0071361=cellular response to ethanol, 0001666=response to hypoxia" "CG1600, Death Resistor Adh domain containing Target" "IPR002085=Alcohol dehydrogenase superfamily, zinc-type, IPR016040=NAD(P)-binding domain, IPR011032=GroES-like" CG1600 16-Dec-15 2015_12 WBGene00014096(ZK829.7) viable FBgn0264793 CR44023 http://flybase.net/reports/FBgn0264793.html non_protein_coding_gene CR44023 16-Dec-15 2015_12 FBgn0004690 ptd parted http://flybase.net/reports/FBgn0004690.html gene 16-Dec-15 2015_12 "visible,heat sensitive,male fertile,viable,female sterile" wing FBgn0066315 APP.s APP.s http://flybase.net/reports/FBgn0066315.html gene APP s 16-Dec-15 2015_12 FBgn0267114 CR45554 http://flybase.net/reports/FBgn0267114.html non_protein_coding_gene CR45554 16-Dec-15 2015_12 FBgn0029810 CG12239 http://flybase.net/reports/FBgn0029810.html protein_coding_gene CG12239 16-Dec-15 2015_12 viable FBgn0036752 Adgf-A Adenosine deaminase-related growth factor A http://flybase.net/reports/FBgn0036752.html protein_coding_gene "0004000=adenosine deaminase activity, 0008083=growth factor activity" "0042386=hemocyte differentiation, 0006109=regulation of carbohydrate metabolic process, 0043103=hypoxanthine salvage, 0035167=larval lymph gland hemopoiesis, 0046103=inosine biosynthetic process, 0008283=cell proliferation, 0006154=adenosine catabolic process, 0043617=cellular response to sucrose starvation" "0005615=extracellular space, 0005829=cytosol" "adgf-a, adenosine deaminase, adgfa, CG5992, ADGDF-A, Adgf-a, ADGF-A, AdgfA" "IPR006331=Adenosine deaminase-related growth factor, IPR013659=Adenosine/AMP deaminase N-terminal, IPR001365=Adenosine/AMP deaminase domain" CG5992 16-Dec-15 2015_12 "ENSDARG00000051744,ENSDARG00000051746(cecr1a),ENSDARG00000015623(cecr1b)" ENSXETG00000000874(CECR1) ENSG00000093072(CECR1) "melanotic mass phenotype,viable,fertile,lethal - all die before end of larval stage,some die during larval stage,developmental rate defective,lethal" "melanotic mass,embryonic/larval fat body,pupal abdomen,adult abdomen,lamellocyte,crystal cell,embryonic/larval lymph gland,sessile hemocyte,embryonic/larval hemocyte" FBgn0066123 E(sda)L E(sda)L http://flybase.net/reports/FBgn0066123.html gene Line L 16-Dec-15 2015_12 FBgn0263662 CR43653 http://flybase.net/reports/FBgn0263662.html non_protein_coding_gene CR43653 16-Dec-15 2015_12 FBgn0064225 RpL5 Ribosomal protein L5 http://flybase.net/reports/FBgn0064225.html "FBan0017489, FBgn0040008, FBgn0040061" protein_coding_gene "0005515=protein binding, 0003723=RNA binding, 0003735=structural constituent of ribosome, 0008097=5S rRNA binding" "0006412=translation, 0000027=ribosomal large subunit assembly" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "Rp L5, dRPL5, M(2)40B, E-2d, yippee interacting protein 6, yip6, Enhancer on chromosome 2, complementation group d, L5, Rpl5, CG17489, ribosomal protein L5" "IPR005485=Ribosomal protein L5 eukaryotic/L18 archaeal, IPR025607=Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal, IPR005484=Ribosomal protein L18/L5" CG17489 16-Dec-15 2015_12 "ENSDARG00000015862(rpl5b),ENSDARG00000020197(rpl5a)" YPL131W(RPL5) WBGene00004416(rpl-5) ENSXETG00000023004(Q6PBE3_XENTR) ENSMUSG00000058558(Rpl5) ENSG00000122406(RPL5) "lethal - all die before end of larval stage,some die during larval stage,small body,Minute,dominant,developmental rate defective,increased cell size,decreased cell number,recessive,size defective" "chaeta,macrochaeta,adult heart" DRSC03801 IEK -2.251217493 -1.894209947 0.188390433 -5.508396791 3.176023874 1.939396561 FBgn0010174 RpA-30 Replication Protein A 30 http://flybase.net/reports/FBgn0010174.html gene 0003697=single-stranded DNA binding 0006261=DNA-dependent DNA replication "0005662=DNA replication factor A complex, 0005634=nucleus" "Drosophila Replication Protein A, RP-A, RPA, RPA30, DRP-A, RPA 30 kDa, dRP-A, D-SSB, DmRPA, Single stranded-binding protein 30, Ssb-30, DmRP-A" 16-Dec-15 2015_12 embryonic stage FBgn0031398 CG10880 http://flybase.net/reports/FBgn0031398.html protein_coding_gene IPR016024=Armadillo-type fold CG10880 16-Dec-15 2015_12 "female sterile,viable" FBgn0026190 PH4ë±MP prolyl-4-hydroxylase-alpha MP http://flybase.net/reports/FBgn0026190.html FBgn0015713 protein_coding_gene "0005506=iron ion binding, 0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" 0016222=procollagen-proline 4-dioxygenase complex "CG9726, PH4alphaMP, prolyl-4-hydroxylase-alpha, 59D7T, ESTS:59D7T, alpha subunit, DM59D7T" "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG9726 16-Dec-15 2015_12 "viable,fertile" FBgn0262150 CG42876 http://flybase.net/reports/FBgn0262150.html protein_coding_gene CG42876 16-Dec-15 2015_12 FBgn0003706 tipA temperature-induced paralytic A http://flybase.net/reports/FBgn0003706.html gene temperature induced paralysis A 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0015444 l(1)7Da lethal (1) 7Da http://flybase.net/reports/FBgn0015444.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040799 CG13051 http://flybase.net/reports/FBgn0040799.html protein_coding_gene CG13051 16-Dec-15 2015_12 FBgn0001846 l(1)ts3733 lethal (1) ts3733 http://flybase.net/reports/FBgn0001846.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0060392 l(3)S133610 lethal (3) S133610 http://flybase.net/reports/FBgn0060392.html gene 1336/10 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266262 CR44957 http://flybase.net/reports/FBgn0266262.html non_protein_coding_gene CR44957 16-Dec-15 2015_12 FBgn0263746 CR43671 http://flybase.net/reports/FBgn0263746.html FBgn0051782 pseudogene_attribute CG31782 CR43671 16-Dec-15 2015_12 FBgn0260488 l(3)1025 http://flybase.net/reports/FBgn0260488.html gene 0097155=fasciculation of sensory neuron axon 16-Dec-15 2015_12 neuroanatomy defective dendritic arborizing neuron FBgn0053721 CG33721 http://flybase.net/reports/FBgn0053721.html protein_coding_gene CR33721 IPR010512=Protein of unknown function DUF1091 CG33721 16-Dec-15 2015_12 FBgn0010680 l(2)s1878 lethal (2) s1878 http://flybase.net/reports/FBgn0010680.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013248 E(var)3-13 E(var)3-13 http://flybase.net/reports/FBgn0013248.html gene E-var(3)13 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0005328 P37 P37 http://flybase.net/reports/FBgn0005328.html gene 16-Dec-15 2015_12 "optomotor response defective,phototaxis defective,flight defective,behavior defective" FBgn0040162 l(1)G0442 lethal (1) G0442 http://flybase.net/reports/FBgn0040162.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0027548 nito spenito http://flybase.net/reports/FBgn0027548.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0048749=compound eye development, 0000398=mRNA splicing, via spliceosome, 0010628=positive regulation of gene expression, 0035222=wing disc pattern formation, 0030177=positive regulation of Wnt signaling pathway, 0022008=neurogenesis" 0071011=precatalytic spliceosome "SSLP, BcDNA:GH11110, Spenito, Spen-like protein, Dm44A/spenito, One Twenty Two, cg2910, CG2910, DmSSp, Nito, dOTT" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR016194=SPOC-like, C-terminal domain, IPR012921=Spen paralogue and orthologue SPOC, C-terminal, IPR000504=RNA recognition motif domain, IPR010912=Spen paralogue/orthologue C-terminal, metazoa" CG2910 16-Dec-15 2015_12 WBGene00017929(F29C4.7) "ENSXETG00000000072(RBM15B),ENSXETG00000002029(RBM15)" "ENSMUSG00000045365,ENSMUSG00000048109(Rbm15)" "ENSG00000179837(RBM15B),ENSG00000162775(RBM15)" "visible,increased cell death,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "eye photoreceptor cell,ommatidium,rhabdomeresev.PR,eye,posterior,eye disc,ganglion mother cell" DRSC05943 IE 2.044670248 1.27712455 4.466775364 1.017266983 -0.93225926 0.184211916 FBgn0050218 tRNA:CR30218 transfer RNA:CR30218 http://flybase.net/reports/FBgn0050218.html "FBgn0011922, FBgn0060136" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033436=AUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna37-MetCAT, tRNA:met3:56EF, tRNA:M:CAT:AE002787-e, CR30218, tRNA:M3:56EF, transfer RNA:met3:56EF, AE002787.trna54-MetCAT, tRNA[Met-ATG]" CR30218 16-Dec-15 2015_12 FBgn0022124 l(2)k06506 lethal (2) k06506 http://flybase.net/reports/FBgn0022124.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260489 l(3)9374 http://flybase.net/reports/FBgn0260489.html gene "0048813=dendrite morphogenesis, 0097155=fasciculation of sensory neuron axon" 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,axon,dendrite" FBgn0259927 CG42450 http://flybase.net/reports/FBgn0259927.html "FBgn0052543, FBgn0030962" protein_coding_gene 0004871=signal transducer activity "0035556=intracellular signal transduction, 0038032=termination of G-protein coupled receptor signaling pathway, 0008277=regulation of G-protein coupled receptor protein signaling pathway" 0005834=heterotrimeric G-protein complex "CG7095, CG32543" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR016137=RGS domain, IPR015898=G-protein gamma-like domain, IPR000591=DEP domain, IPR024066=RGS, subdomain 1" CG42450 16-Dec-15 2015_12 FBgn0036035 CG18178 http://flybase.net/reports/FBgn0036035.html protein_coding_gene 0000166=nucleotide binding IPR012677=Nucleotide-binding alpha-beta plait domain CG18178 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0002303 l(3)84Bc lethal (3) 84Bc http://flybase.net/reports/FBgn0002303.html gene l(3)84Bb 16-Dec-15 2015_12 "lethal,recessive" FBgn0020504 C43 C43 http://flybase.net/reports/FBgn0020504.html gene unnamed 16-Dec-15 2015_12 FBgn0034197 Cda9 Chitin deacetylase-like 9 http://flybase.net/reports/FBgn0034197.html protein_coding_gene "0016810=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds" 0005975=carbohydrate metabolic process "CG15918, DmCDA9" "IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002509=NodB homology domain" CG15918 16-Dec-15 2015_12 viable FBgn0052270 CG32270 http://flybase.net/reports/FBgn0052270.html "FBgn0035419, FBgn0053161, FBtr0073100, FBpp0072962, FBtr0073101, FBpp0072963" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG33161, SP124, CG11530" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG32270 16-Dec-15 2015_12 FBgn0038055 trus toys are us http://flybase.net/reports/FBgn0038055.html protein_coding_gene 0005737=cytoplasm CG5333 "IPR007320=Programmed cell death protein 2, C-terminal" CG5333 16-Dec-15 2015_12 ENSXETG00000020032(BC079944.1) ENSMUSG00000002635(Pdcd2l) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0261353 Ccdc56 Coiled-coil domain containing 56 http://flybase.net/reports/FBgn0261353.html "FBan0007319, FBgn0036197" protein_coding_gene 0097034=mitochondrial respiratory chain complex IV biogenesis 0005739=mitochondrion "Mitochondrial Transcription Factor B1, CCDC56, ccdc56, coiled-coil domain containing 56, CG42630, CG7319" CG42630 16-Dec-15 2015_12 "viable,dominant,fertile,developmental rate defective,recessive,size defective,lethal - all die before end of larval stage,some die during third instar larval stage,increased cell death" wing disc FBgn0033028 CG11665 http://flybase.net/reports/FBgn0033028.html protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG11665 16-Dec-15 2015_12 "YOR306C(MCH5),YOL119C(MCH4)" viable DRSC04853 IK -0.14177668 -1.538081267 -0.117887069 0.37968824 -1.560640833 0.647303658 FBgn0266582 ND-30 NADH dehydrogenase (ubiquinone) 30 kDa subunit http://flybase.net/reports/FBgn0266582.html "FBgn0266551, FBgn0035404" protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" 0055114=oxidation-reduction process "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "NADH dehydrogenase (ubiquinone) Fe-S protein 3, NUGM, NADH-UBIQUINONE OXIDOREDUCTASE 30 KDA SUBUNIT, nuclear-encoded subunit NDUFS3 of complex I, CG 12079, NADH:ubiquinone oxidoreductase 30 kDa subunit, C-I-NDUFS3, NADH ubiquinone oxidoreductase 30 kDa, NDUFS3, CG12079" "IPR010218=NADH dehydrogenase, subunit C, IPR001268=NADH:ubiquinone oxidoreductase, 30kDa subunit, IPR020396=NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site" CG12079 16-Dec-15 2015_12 ENSDARG00000015385(ndufs3) WBGene00020417(nuo-2) ENSXETG00000019932(ndufs3) ENSMUSG00000005510(Ndufs3) ENSG00000213619(NDUFS3) FBgn0259198 CG42302 http://flybase.net/reports/FBgn0259198.html "FBgn0046520, FBgn0046521, FBan0006857, FBgn0030950" protein_coding_gene CG6857 IPR004217=Tim10/DDP family zinc finger CG42302 16-Dec-15 2015_12 YGR181W(TIM13) FBgn0027073 CG4302 http://flybase.net/reports/FBgn0027073.html FBgn0034604 protein_coding_gene "0016758=transferase activity, transferring hexosyl groups, 0008194=UDP-glycosyltransferase activity" 0006011=UDP-glucose metabolic process 0005783=endoplasmic reticulum "BEST:GH09393, GH09393" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG4302 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0027382 Idefix\env env http://flybase.net/reports/FBgn0027382.html transposable_element_gene "ORF3, env" "IPR012014=Retroelement-encoded protein, env-related" 16-Dec-15 2015_12 FBgn0259416 C606 http://flybase.net/reports/FBgn0259416.html gene 16-Dec-15 2015_12 visible "wing hair,wing margin,chaeta" FBgn0031718 CG14014 http://flybase.net/reports/FBgn0031718.html protein_coding_gene 0046983=protein dimerization activity CG14014 16-Dec-15 2015_12 viable FBgn0050477 CG30477 http://flybase.net/reports/FBgn0050477.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264667 topiary topiary http://flybase.net/reports/FBgn0264667.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0085682 CG41551 http://flybase.net/reports/FBgn0085682.html FBan0041551 protein_coding_gene 16-Dec-15 2015_12 FBgn0058373 CG40373 http://flybase.net/reports/FBgn0058373.html protein_coding_gene 16-Dec-15 2015_12 FBgn0259548 GG01153 http://flybase.net/reports/FBgn0259548.html gene 16-Dec-15 2015_12 visible "tarsal segment,metathoracic leg" FBgn0038828 CG17270 http://flybase.net/reports/FBgn0038828.html FBgn0025281 protein_coding_gene 0016021=integral component of membrane anon-Liu IPR005352=Erg28 CG17270 16-Dec-15 2015_12 ENSXETG00000006115(TTpA001n02.1) viable FBgn0260082 2L1687 http://flybase.net/reports/FBgn0260082.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0023523 Or2a Odorant receptor 2a http://flybase.net/reports/FBgn0023523.html protein_coding_gene "0005549=odorant binding, 0004888=transmembrane signaling receptor activity, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "Odorant receptor 62, 2a, DOR2F.1, EG:30B8.7, Dor62, Olfactory receptor 2F.1, AN4, dor62, Or2F.1, Or62, DOR62, or2a, CG3206, 2F.1" "IPR004117=Olfactory receptor, Drosophila" CG3206 16-Dec-15 2015_12 adult stage sensory neuron &&of antennal segment 3

"smell perception defective,viable" FBgn0084954 Rst(2b)Cyr Resistance 2b Cyromazine http://flybase.net/reports/FBgn0084954.html gene 16-Dec-15 2015_12 "chemical resistant,dominant,partially" FBgn0037011 CG4858 http://flybase.net/reports/FBgn0037011.html protein_coding_gene "0005524=ATP binding, 0051539=4 iron, 4 sulfur cluster binding, 0000166=nucleotide binding" 0016226=iron-sulfur cluster assembly Nubp2 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000808=Mrp, conserved site, IPR028600=Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes, IPR019591=Mrp/NBP35 ATP-binding protein" CG4858 16-Dec-15 2015_12 ENSDARG00000055653 YIL003W(CFD1) ENSXETG00000010354(NUBP2) ENSMUSG00000039183(Nubp2) ENSG00000095906(NUBP2) "viable,locomotor rhythm defective" FBgn0004766 l(3)89Dc lethal (3) 89Dc http://flybase.net/reports/FBgn0004766.html gene 16-Dec-15 2015_12 lethal FBgn0035676 ssp6 short spindle 6 http://flybase.net/reports/FBgn0035676.html protein_coding_gene 0090307=mitotic spindle assembly "Ssp6, CG6619" IPR001478=PDZ domain CG6619 16-Dec-15 2015_12 "ENSDARG00000027600(zgc:56116),ENSDARG00000019202(ldb3b)" ENSXETG00000016085(GRID2IP) "partially lethal - majority die,some die during pupal stage" DRSC10677 IEK -0.458912462 -3.509548101 -0.308570846 -4.480065682 -1.12833743 -1.73606069 FBgn0030268 Klp10A Kinesin-like protein at 10A http://flybase.net/reports/FBgn0030268.html FBgn0066848 protein_coding_gene "0005524=ATP binding, 0008574=ATP-dependent microtubule motor activity, plus-end-directed, 0008017=microtubule binding, 0003774=motor activity" "0007052=mitotic spindle organization, 0007019=microtubule depolymerization, 0000070=mitotic sister chromatid segregation, 0090307=mitotic spindle assembly, 0007057=spindle assembly involved in female meiosis I, 0007079=mitotic chromosome movement towards spindle pole, 0051298=centrosome duplication, 0051296=establishment of meiotic spindle orientation, 0007051=spindle organization, 0000212=meiotic spindle organization" "0055028=cortical microtubule, 0005813=centrosome, 0090619=meiotic spindle pole, 0072687=meiotic spindle, 0097431=mitotic spindle pole, 0000922=spindle pole, 0005828=kinetochore microtubule, 0000775=chromosome, centromeric region, 0061673=mitotic spindle astral microtubule, 0005871=kinesin complex" "DmKLP10A, Kif2A, KLP10a, KIF 2A, KLP10A, kinesin-like protein 10A, kinesin-13, kinesin-13 motor, DmKlp10A, Kinesin-like protein at 10A, KIF2A/B/C, Klp10A, CG1453, klp10A, anon-WO03040301.142, DmCG1453" "IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027640=Kinesin-like protein" CG1453 16-Dec-15 2015_12 ENSDARG00000043571(zgc:103670) WBGene00002219(klp-7) ENSXETG00000014831(KIF2A) "ENSMUSG00000021693(Kif2a),ENSMUSG00000028678(Kif2c)" ENSG00000068796(KIF2A) "lethal,germline clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,mitotic cell cycle defective,visible" "meiotic spindlenos.UTR.THsimVP16,meiotic spindle | female | germline clone,meiotic spindle | femalenos.UTR.THsimVP16,meiotic spindle | femalemat.ë±Tub67C.THsimVP16,spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,S2 cell-line,spindle,microtubule,trichogen cell,wing disc,centriole" DRSC19601 K 0.565050112 -0.792925128 0.569719888 0.452311565 1.535140515 0.28134973 FBgn0037979 GCC185 GCC185 ortholog (H. sapiens) http://flybase.net/reports/FBgn0037979.html protein_coding_gene "0030306=ADP-ribosylation factor binding, 0042803=protein homodimerization activity, 0042802=identical protein binding, 0017137=Rab GTPase binding" "0048193=Golgi vesicle transport, 0000042=protein targeting to Golgi, 0042147=retrograde transport, endosome to Golgi, 0034067=protein localization to Golgi apparatus" "0005794=Golgi apparatus, 0000138=Golgi trans cisterna" "dGCC185, CG3532" IPR000237=GRIP CG3532 16-Dec-15 2015_12 WBGene00011503(T05G5.9) ENSMUSG00000038039(Gcc2) ENSG00000135968(GCC2) viable FBgn0019682 mor(1)1 mortality gene (1)1 http://flybase.net/reports/FBgn0019682.html gene 16-Dec-15 2015_12 short lived FBgn0084048 CR41184 http://flybase.net/reports/FBgn0084048.html FBan0041184 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0003098 PL(1)sp-S2 Polygenic locus sternopleural S2 http://flybase.net/reports/FBgn0003098.html gene PL(1)sp[S2] 16-Dec-15 2015_12 FBgn0030329 prtp pretaporter http://flybase.net/reports/FBgn0030329.html FBgn0027709 protein_coding_gene 0003756=protein disulfide isomerase activity "2000427=positive regulation of apoptotic cell clearance, 0043277=apoptotic cell clearance, 0045454=cell redox homeostasis" "0012505=endomembrane system, 0009986=cell surface, 0005783=endoplasmic reticulum" "pret-a-porter, anon-EST:Posey253, pretaporter, p47, Pretaporter, prtp, CG1837" "IPR013766=Thioredoxin domain, IPR017937=Thioredoxin, conserved site, IPR012336=Thioredoxin-like fold, IPR005788=Disulphide isomerase" CG1837 16-Dec-15 2015_12 ENSDARG00000009342(txndc5) YIL005W(EPS1) ENSXETG00000020457(txndc5) ENSMUSG00000038991(Txndc5) ENSG00000188428(TXNDC5) viable "embryonic hemocyte,embryonic/larval glial cell" FBgn0025505 l(3)72Fb lethal (3) 72Fb http://flybase.net/reports/FBgn0025505.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003358 Jon99Ci Jonah 99Ci http://flybase.net/reports/FBgn0003358.html "FBgn0001288, FBgn0051039" protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" "0006508=proteolysis, 0007586=digestion" "SER3, CG31039, JonC, Jon99Calphai, CG17951, Ser99Dc, Serine protease 3, Jon99C1, Jon99Cbeta, Ser3, Jonah 99C Beta, Jon99C, SP150, Jon99B, Jon99C2, serine protease, 143341_at, Jon99Cbetai, Jonah 99C Alpha, Jon99Calpha, ser99Dc, 99Calpha" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG31039 16-Dec-15 2015_12 viable FBgn0039503 CG14262 http://flybase.net/reports/FBgn0039503.html protein_coding_gene "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG14262 16-Dec-15 2015_12 viable FBgn0267185 CR45625 http://flybase.net/reports/FBgn0267185.html non_protein_coding_gene CR45625 16-Dec-15 2015_12 FBgn0038701 CG18493 http://flybase.net/reports/FBgn0038701.html protein_coding_gene 0008236=serine-type peptidase activity 0006508=proteolysis "IPR008758=Peptidase S28, IPR029058=Alpha/Beta hydrolase fold" CG18493 16-Dec-15 2015_12 viable FBgn0001046 fs(3)HO133 female sterile (3) HO133 http://flybase.net/reports/FBgn0001046.html gene fs(3)133A 16-Dec-15 2015_12 female sterile oocyte FBgn0041758 eth-as312 eth-as312 http://flybase.net/reports/FBgn0041758.html gene eth[as]312 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0069330 X-103-22 X-103-22 http://flybase.net/reports/FBgn0069330.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,germline clone,maternal effect,embryonic head" FBgn0040084 p76 p76 http://flybase.net/reports/FBgn0040084.html gene 16-Dec-15 2015_12 FBgn0283476 Dhc16F Dynein heavy chain at 16F http://flybase.net/reports/FBgn0283476.html "FBgn0013809, FBgn0004671" protein_coding_gene "0005524=ATP binding, 0003774=motor activity, 0003777=microtubule motor activity, 0016887=ATPase activity, 0042623=ATPase activity, coupled" "0007018=microtubule-based movement, 0001539=cilium or flagellum-dependent cell motility" "0005875=microtubule associated complex, 0005858=axonemal dynein complex" "Dhc, dhc, crossveinless-like 6, unnamed, DHC, CG7092, dynein-related heavy chain polypeptide, atoll, cvl-6" "IPR026980=Dynein heavy chain 6, axonemal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR025662=Sigma-54 interaction domain, ATP-binding site 1, IPR004273=Dynein heavy chain domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR011704=ATPase, dynein-related, AAA domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR013602=Dynein heavy chain, domain-2" CG7092 16-Dec-15 2015_12 ENSDARG00000000606(LOC100148193) ENSMUSG00000052861(Dnahc6) ENSG00000115423(DNAH6) FBgn0086533 snoRNA:Me18S-C419 http://flybase.net/reports/FBgn0086533.html snoRNA_gene "Me18S-C419, Me18S-Cm419, snoRNA:RpL15-a" CR43566 16-Dec-15 2015_12 FBgn0261959 EU820 http://flybase.net/reports/FBgn0261959.html gene 16-Dec-15 2015_12 viable FBgn0002866 mtb matt brown http://flybase.net/reports/FBgn0002866.html gene 16-Dec-15 2015_12 "male sterile,visible,viable,male,poor,eye color defective" "wing,eye" FBgn0028372 isopeptidase-T-3 isopeptidase-T-3 http://flybase.net/reports/FBgn0028372.html protein_coding_gene "isopeptidase T-3, IsoT-3, CG11025, ISOT-3" "IPR009060=UBA-like, IPR015940=Ubiquitin-associated domain" CG11025 16-Dec-15 2015_12 ENSDARG00000059722(si:dkey-1o2.1) ENSXETG00000021621(UBAC1) ENSMUSG00000036352(Ubac1) ENSG00000130560(UBAC1) viable FBgn0028193 l(3)S022564 lethal (3) S022564 http://flybase.net/reports/FBgn0028193.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264600 CR43949 http://flybase.net/reports/FBgn0264600.html non_protein_coding_gene CG43949 CR43949 16-Dec-15 2015_12 FBgn0259239 CG42337 http://flybase.net/reports/FBgn0259239.html "FBgn0037053, FBgn0037052" protein_coding_gene "CG12976, CG12977" CG42337 16-Dec-15 2015_12 FBgn0062601 Mod(var)1453 Mod(var)1453 http://flybase.net/reports/FBgn0062601.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1453 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002153 l(2)mbn lethal (2) malignant blood neoplasm http://flybase.net/reports/FBgn0002153.html gene "mbn-2, malignant blood neoplasm-1, mbn2" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "plasmatocyte,podocyte,crystal cell,embryonic/larval lymph gland" FBgn0029667 Gas8 Growth arrest specific protein 8 http://flybase.net/reports/FBgn0029667.html protein_coding_gene 0030317=sperm motility "0031514=motile cilium, 0005737=cytoplasm" CG14271 IPR025593=Growth arrest-specific protein 8 CG14271 16-Dec-15 2015_12 ENSDARG00000040871(gas8) ENSXETG00000019848(GAS8) ENSMUSG00000040220(Gas8) ENSG00000141013(GAS8) viable FBgn0259672 B0674 http://flybase.net/reports/FBgn0259672.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,proboscis,arista" FBgn0030117 ric8b ric8b http://flybase.net/reports/FBgn0030117.html FBpp0071253 pseudogene_attribute "ric-8b, CR15910, CG15910" CR15910 16-Dec-15 2015_12 FBgn0025373 Fpps Farnesyl pyrophosphate synthase http://flybase.net/reports/FBgn0025373.html "FBgn0022145, FBgn0042628" protein_coding_gene "0004337=geranyltranstransferase activity, 0004161=dimethylallyltranstransferase activity" "0045337=farnesyl diphosphate biosynthetic process, 0008354=germ cell migration, 0008299=isoprenoid biosynthetic process, 0035220=wing disc development" "DmFPS, CG12389, FPPS, l(2)k06103, farnesyl diphosphase synthase, farnesyl diphosphate synthase, v(2)k03514, FPS, DmFPPS, Farnesyl diphosphate synthase, DmFPPSase, fps, fpps" "IPR008949=Isoprenoid synthase domain, IPR000092=Polyprenyl synthetase" CG12389 16-Dec-15 2015_12 ENSDARG00000040890(fdps) YJL167W(ERG20) WBGene00011058(R06C1.2) ENSMUSG00000059743(Fdps) ENSG00000160752(FDPS) "viable,lethal,recessive,visible" "crystal cell,pole cell,germline clone,rescuable maternal effect,pole cell & embryonic nervous system" FBgn0017367 l(3)89Bo lethal (3) 89Bo http://flybase.net/reports/FBgn0017367.html gene l(3)89Bm 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority live" FBgn0265040 CR44157 http://flybase.net/reports/FBgn0265040.html non_protein_coding_gene CR44157 16-Dec-15 2015_12 FBgn0025838 CG2652 http://flybase.net/reports/FBgn0025838.html protein_coding_gene "0006355=regulation of transcription, DNA-templated" EG:155E2.5 IPR005033=YEATS CG2652 16-Dec-15 2015_12 "viable,fertile" FBgn0083116 W12 W12 http://flybase.net/reports/FBgn0083116.html gene 16-Dec-15 2015_12 viable wing FBgn0032850 Kua Kua http://flybase.net/reports/FBgn0032850.html protein_coding_gene 0080132=fatty acid alpha-hydroxylase activity 0016021=integral component of membrane "38B.18, CG10723" "IPR019547=B domain of TMEM189, localisation domain" CG10723 16-Dec-15 2015_12 "ENSDARG00000011498(si:ch211-212o1.2),ENSDARG00000042732(tmem189)" WBGene00013136(Y53C10A.5) ENSXETG00000024004(TMEM189) ENSMUSG00000019755(Tmem189) ENSG00000124208(TMEM189-UBE2V1) viable FBgn0010663 l(2)10491 lethal (2) 10491 http://flybase.net/reports/FBgn0010663.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0262687 CR43157 http://flybase.net/reports/FBgn0262687.html non_protein_coding_gene CR43157 16-Dec-15 2015_12 FBgn0085619 CG41329 http://flybase.net/reports/FBgn0085619.html FBan0041329 protein_coding_gene 16-Dec-15 2015_12 FBgn0250785 vari varicose http://flybase.net/reports/FBgn0250785.html "FBgn0010560, FBpp0088886, FBtr0089947, FBpp0088885, FBtr0089946, FBpp0088884, FBtr0089945, FBgn0032885, FBgn0025170" protein_coding_gene 0004385=guanylate kinase activity "0035159=regulation of tube length, open tracheal system, 0035151=regulation of tube size, open tracheal system, 0007424=open tracheal system development, 0019991=septate junction assembly, 0035001=dorsal trunk growth, open tracheal system" "0016328=lateral plasma membrane, 0005918=septate junction, 0016020=membrane" "senz-aria, Vari, Varicose, l(2)38EFa, CG9326, l(2)03953b, 38E.21, l(2)03953, senz'aria, szar, lethal (2) 38EFa" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014775=L27 domain, C-terminal, IPR004172=L27 domain, IPR008144=Guanylate kinase-like domain, IPR020590=Guanylate kinase, conserved site, IPR001452=SH3 domain, IPR011511=Variant SH3 domain, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR001478=PDZ domain" CG9326 16-Dec-15 2015_12 "ENSDARG00000029761(mpp6b),ENSDARG00000010957(mpp2b),ENSDARG00000056892(mpp6a),ENSDARG00000053453(mpp2a)" "ENSMUSG00000038388(Mpp6),ENSMUSG00000017314(Mpp2)" FBgn0052461 CG32461 http://flybase.net/reports/FBgn0052461.html protein_coding_gene CG32461 16-Dec-15 2015_12 viable FBgn0016932 smi51A smell impaired 51A http://flybase.net/reports/FBgn0016932.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0259985 Mppe Metallophosphoesterase http://flybase.net/reports/FBgn0259985.html "FBgn0033675, FBgn0086293" protein_coding_gene 0016791=phosphatase activity 0006470=protein dephosphorylation 0005794=Golgi apparatus "11471, GS11471, metallophosphoesterase, dmppe, dMPPE, CG8889" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like" CG8889 16-Dec-15 2015_12 WBGene00014079(ZK792.7) FBgn0004988 Branchlet Branchlet http://flybase.net/reports/FBgn0004988.html gene 0008586=imaginal disc-derived wing vein morphogenesis Bt 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "wing,posterior crossvein,adult abdominal segment" FBgn0031388 CG12674 http://flybase.net/reports/FBgn0031388.html protein_coding_gene "0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter" 0016593=Cdc73/Paf1 complex IPR007133=RNA polymerase II associated factor Paf1 CG12674 16-Dec-15 2015_12 viable FBgn0015004 ACE3 Amplification-control-element-on-3 http://flybase.net/reports/FBgn0015004.html region ACE-3 16-Dec-15 2015_12 FBgn0266088 CR44830 http://flybase.net/reports/FBgn0266088.html non_protein_coding_gene CR44830 16-Dec-15 2015_12 FBgn0031337 CG14346 http://flybase.net/reports/FBgn0031337.html protein_coding_gene CG14346 16-Dec-15 2015_12 viable FBgn0044047 Ilp6 Insulin-like peptide 6 http://flybase.net/reports/FBgn0044047.html FBgn0029612 protein_coding_gene "0005179=hormone activity, 0005158=insulin receptor binding" "0008286=insulin receptor signaling pathway, 0040018=positive regulation of multicellular organism growth" 0005615=extracellular space "Drosophila insulin-like peptide 6, Ilp-6, Dilp 6, ilp6, Dilp6, dilp6, DILP-6, Ilp, dilp, Ilp6, dILP6, Dilp, DILP, dIlp6, insulin-like peptide, dilp-6, insulin-like peptide 6, CG14049, DILP6" IPR016179=Insulin-like CG14049 16-Dec-15 2015_12 larval stage | third instar embryonic/larval midgut

"stress response defective,small body,large body,heat sensitive,chemical resistant,viable,fertile,decreased cell number,partially lethal - majority die,some die during pupal stage" embryonic/larval neuroblast FBgn0259588 GG01544 http://flybase.net/reports/FBgn0259588.html gene 16-Dec-15 2015_12 visible wing FBgn0011307 l(3)j1A1 lethal (3) j1A1 http://flybase.net/reports/FBgn0011307.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062565 Or19b Odorant receptor 19b http://flybase.net/reports/FBgn0062565.html FBgn0052825 protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016020=membrane, 0016021=integral component of membrane, 0032590=dendrite membrane" CG32825 "IPR004117=Olfactory receptor, Drosophila" CG32825 16-Dec-15 2015_12 FBgn0264346 CR43802 http://flybase.net/reports/FBgn0264346.html non_protein_coding_gene lincRNA.166 CR43802 16-Dec-15 2015_12 FBgn0052161 CG32161 http://flybase.net/reports/FBgn0052161.html protein_coding_gene CG32161 16-Dec-15 2015_12 viable FBgn0052797 CG32797 http://flybase.net/reports/FBgn0052797.html protein_coding_gene IPR026780=Proline-rich nuclear receptor coactivator 1/2 CG32797 16-Dec-15 2015_12 FBgn0024360 CG11418 http://flybase.net/reports/FBgn0024360.html FBgn0024981 protein_coding_gene 0044822=poly(A) RNA binding 0006378=mRNA polyadenylation 0005739=mitochondrion "DmNP_569904, EG:8D8.8" IPR002058=PAP/25A-associated CG11418 16-Dec-15 2015_12 ENSDARG00000057321(zgc:112254) ENSXETG00000002656(MTPAP) ENSMUSG00000024234(Mtpap) ENSG00000107951(MTPAP) "lethal,some die during pupal stage,some die during larval stage,viable,visible" trichogen cell FBgn0037395 CG10280 http://flybase.net/reports/FBgn0037395.html protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR001506=Peptidase M12A, astacin, IPR024079=Metallopeptidase, catalytic domain, IPR006026=Peptidase, metallopeptidase" CG10280 16-Dec-15 2015_12 "ENSXETG00000000978(BC080921.1),ENSXETG00000024385(BC093465.1),ENSXETG00000013182(),ENSXETG00000000918(),ENSXETG00000024379(TNeu066d14.1),ENSXETG00000000956(),ENSXETG00000025500(),ENSXETG00000021090(),ENSXETG00000009046(),ENSXETG00000015639(),ENSXETG00000022231()" viable FBgn0051265 CG31265 http://flybase.net/reports/FBgn0051265.html FBgn0038480 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG5233, SP126" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG31265 16-Dec-15 2015_12 viable FBgn0028641 fs(2)k09833 fs(2)k09833 http://flybase.net/reports/FBgn0028641.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0029145 P(3)78A P(3)78A http://flybase.net/reports/FBgn0029145.html gene 16-Dec-15 2015_12 FBgn0005082 fs(2)OW806 female sterile (2) OW806 http://flybase.net/reports/FBgn0005082.html gene 16-Dec-15 2015_12 FBgn0032864 CG2493 http://flybase.net/reports/FBgn0032864.html protein_coding_gene 0004185=serine-type carboxypeptidase activity 0006508=proteolysis 38C.55 "IPR029058=Alpha/Beta hydrolase fold, IPR008758=Peptidase S28" CG2493 16-Dec-15 2015_12 ENSDARG00000037883(prcp) "WBGene00022801(pcp-5),WBGene00003956(pcp-1)" ENSMUSG00000061119(Prcp) ENSG00000137509(PRCP) "viable,fertile" FBgn0005417 l(1)adl6 lethal (1) adl6 http://flybase.net/reports/FBgn0005417.html gene l(1)adl-6 16-Dec-15 2015_12 "visible,short lived,heat sensitive,partially lethal - majority die,lethal" eye FBgn0015474 l(2)45Ab lethal (2) 45Ab http://flybase.net/reports/FBgn0015474.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0267556 CR45896 http://flybase.net/reports/FBgn0267556.html non_protein_coding_gene CR45896 16-Dec-15 2015_12 FBgn0032479 CG16974 http://flybase.net/reports/FBgn0032479.html protein_coding_gene 0048812=neuron projection morphogenesis "CT35580, Dromel_CG16974_FBtr0080489_mORF, kekkon-like" "IPR013783=Immunoglobulin-like fold, IPR001611=Leucine-rich repeat, IPR007110=Immunoglobulin-like domain, IPR003591=Leucine-rich repeat, typical subtype, IPR003598=Immunoglobulin subtype 2" CG16974 16-Dec-15 2015_12 WBGene00022580(ZC262.3) viable FBgn0023466 anon-56Cb anon-56Cb http://flybase.net/reports/FBgn0023466.html gene 16-Dec-15 2015_12 adult stage && oogenesis stage ovary

FBgn0014190 hni he's not interested http://flybase.net/reports/FBgn0014190.html gene "0007617=mating behavior, 0007619=courtship behavior" 16-Dec-15 2015_12 FBgn0004062 blt ballet http://flybase.net/reports/FBgn0004062.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,poor,partially lethal - majority die,female" "wing,wing vein" FBgn0000643 fcl foreclosed http://flybase.net/reports/FBgn0000643.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal,recessive,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "chorion | germline clone,dorsal appendage,germline clone,ovary,cuticle,dorsal,embryonic epidermis,embryonic Malpighian tubule" FBgn0031777 CG9154 http://flybase.net/reports/FBgn0031777.html protein_coding_gene "0008168=methyltransferase activity, 0003676=nucleic acid binding" 0032259=methylation "IPR002052=DNA methylase, N-6 adenine-specific, conserved site, IPR019369=Protein-lysine N-methyltransferase Efm5, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG9154 16-Dec-15 2015_12 ENSDARG00000040584(n6amt2) YGR001C() WBGene00043057(M142.8) ENSMUSG00000021951(N6amt2) ENSG00000150456(N6AMT2) "viable,visible" trichogen cell FBgn0083071 ogre::shakB ogre::shakB http://flybase.net/reports/FBgn0083071.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0023225 E(ë_Tub37C1) Enhancer of ë_-Tubulin at 37C http://flybase.net/reports/FBgn0023225.html gene 16-Dec-15 2015_12 FBgn0031808 CG9507 http://flybase.net/reports/FBgn0031808.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR008753=Peptidase M13, N-terminal domain, IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13" CG9507 16-Dec-15 2015_12 viable FBgn0064167 l(3)85.43 lethal (3) 85.43 http://flybase.net/reports/FBgn0064167.html gene 0007300=ovarian nurse cell to oocyte transport 85.43 16-Dec-15 2015_12 lethal oocyte FBgn0266083 ocm over compensating males http://flybase.net/reports/FBgn0266083.html "FBgn0034987, FBgn0262548" protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0035167=larval lymph gland hemopoiesis, 0007549=dosage compensation, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG3363, 166 complementation group, Complementation group A, Mod(GMroX1)A, Mga" "IPR001699=Transcription factor, T-box" CG3363 16-Dec-15 2015_12 DRSC26248 K -0.920089155 0.356804627 -1.031362257 0.212837923 0.38869791 2.474522399 FBgn0039186 CG5746 http://flybase.net/reports/FBgn0039186.html protein_coding_gene CG5746 16-Dec-15 2015_12 FBgn0069247 bop brontops http://flybase.net/reports/FBgn0069247.html gene 0007310=oocyte dorsal/ventral axis specification 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "egg,germline clone,maternal effect,dorsal appendage" FBgn0267530 CR45870 http://flybase.net/reports/FBgn0267530.html non_protein_coding_gene CR45870 16-Dec-15 2015_12 FBgn0004234 l(3)93Bh lethal (3) 93Bh http://flybase.net/reports/FBgn0004234.html gene rlr6 16-Dec-15 2015_12 lethal FBgn0035540 Syx17 Syntaxin 17 http://flybase.net/reports/FBgn0035540.html protein_coding_gene "0000149=SNARE binding, 0005484=SNAP receptor activity, 0032403=protein complex binding" "0010506=regulation of autophagy, 0006888=ER to Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport, 0016081=synaptic vesicle docking, 0097111=endoplasmic reticulum-Golgi intermediate compartment organization, 0007269=neurotransmitter secretion, 0070050=neuron cellular homeostasis, 0009267=cellular response to starvation, 0000046=autophagic vacuole fusion" "0005776=autophagic vacuole, 0031201=SNARE complex, 0000421=autophagic vacuole membrane, 0005886=plasma membrane" "Syx, DmSyx17, CG7452, Dm Syx17, S17, syntaxin, Syntaxin" "IPR000727=Target SNARE coiled-coil homology domain, IPR028676=Syntaxin-17, IPR010989=t-SNARE" CG7452 16-Dec-15 2015_12 ENSDARG00000006869(stx17) ENSMUSG00000061455(Stx17) ENSG00000136874(STX17) "gravitaxis defective,nutrition conditional,locomotor behavior defective,increased cell death,viable,fertile" "embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditionalExel8098),autophagic vacuole | supernumerary | nutrition conditionalExel8098),fat body,adult brain" FBgn0028261 l(3)64Ao lethal (3) 64Ao http://flybase.net/reports/FBgn0028261.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265800 CR44589 http://flybase.net/reports/FBgn0265800.html non_protein_coding_gene CR44589 16-Dec-15 2015_12 FBgn0069962 CG41050 http://flybase.net/reports/FBgn0069962.html FBan0041050 protein_coding_gene 16-Dec-15 2015_12 FBgn0004765 l(3)89Db lethal (3) 89Db http://flybase.net/reports/FBgn0004765.html gene 16-Dec-15 2015_12 lethal FBgn0013697 mt:tRNA:K mitochondrial lysine tRNA http://flybase.net/reports/FBgn0013697.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006299, mt-tRNA[Lys] (CUU), CR34070, tRNA[Lys]" CR34070 16-Dec-15 2015_12 FBgn0021939 l(2)k10815 lethal (2) k10815 http://flybase.net/reports/FBgn0021939.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027192 l(2)56CDa lethal (2) 56CDa http://flybase.net/reports/FBgn0027192.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0021915 l(2)k11404 lethal (2) k11404 http://flybase.net/reports/FBgn0021915.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085602 CG41293 http://flybase.net/reports/FBgn0085602.html FBan0041293 protein_coding_gene 16-Dec-15 2015_12 FBgn0001357 l(1)1EFf lethal (1) 1EFf http://flybase.net/reports/FBgn0001357.html gene l(1)BA6 16-Dec-15 2015_12 lethal FBgn0051167 tRNA:CR31167 transfer RNA:CR31167 http://flybase.net/reports/FBgn0051167.html "FBgn0011968, FBgn0011969, FBgn0011972, FBgn0060057" tRNA_gene "0033446=AGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:S, tRNA:S2b:94A, tRNA[Ser][[2b]], chr3R.trna44-SerGCT, transfer RNA:ser, tRNA[[Ser]], transfer RNA:ser2b, tRNA:S2b, AE002708.trna38-SerGCT, transfer RNA:ser2b:94A, CR31167, tRNA:ser, tRNA:ser2b:94A, tRNA:ser2b, tRNA:S:GCT:AE002708-c" CR31167 16-Dec-15 2015_12 FBgn0035567 CG7514 http://flybase.net/reports/FBgn0035567.html protein_coding_gene "0015367=oxoglutarate:malate antiporter activity, 0022857=transmembrane transporter activity" "0015743=malate transport, 0006839=mitochondrial transport, 0015742=alpha-ketoglutarate transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG7514 16-Dec-15 2015_12 ENSDARG00000035741(zgc:86898) "viable,fertile" DRSC08597 K 0.683349386 0.23126407 0.546586326 -0.04709146 -0.513419799 1.560527119 FBgn0053412 5SrRNA:CR33412 5SrRNA:CR33412 http://flybase.net/reports/FBgn0053412.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33412 CR33412 16-Dec-15 2015_12 FBgn0260479 CG31904 http://flybase.net/reports/FBgn0260479.html "FBgn0051904, FBgn0045953" protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity" 0006836=neurotransmitter transport 0016021=integral component of membrane "anon-WO0149848.5, CG31904-PD" IPR000175=Sodium:neurotransmitter symporter CG31904 16-Dec-15 2015_12 FBgn0263395 hppy happyhour http://flybase.net/reports/FBgn0263395.html "FBgn0065486, FBgn0259477, FBgn0045883, FBgn0034421, FBgn0263255" protein_coding_gene "0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0043065=positive regulation of apoptotic process, 0046330=positive regulation of JNK cascade, 0007030=Golgi organization, 0070328=triglyceride homeostasis, 0006915=apoptotic process, 0032006=regulation of TOR signaling, 0008361=regulation of cell size, 0032008=positive regulation of TOR signaling, 0007254=JNK cascade, 0006468=protein phosphorylation, 0046626=regulation of insulin receptor signaling pathway, 0040009=regulation of growth rate, 0048149=behavioral response to ethanol, 0042059=negative regulation of epidermal growth factor receptor signaling pathway" "0031931=TORC1 complex, 0005737=cytoplasm" "GLK/KHS1, anon-WO0153538.68, EP-704, l(2)SH1261, lethal (2) SH1261, CG7097, CG7097/hppy, l(2)SH2 1261, Gene 2, MAP4K3" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR021160=Mitogen-activated protein (MAP) kinase kinase kinase kinase, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR001180=Citron homology (CNH) domain" CG7097 16-Dec-15 2015_12 ENSDARG00000039125(map4k5) WBGene00022603(gck-2) "ENSXETG00000018501(MAP4K3),ENSXETG00000009127(MAP4K5)" "ENSMUSG00000024242(Map4k3),ENSMUSG00000034761(Map4k5)" "ENSG00000011566(MAP4K3),ENSG00000012983(MAP4K5)" FBgn0015447 l(1)8Ae lethal (1) 8Ae http://flybase.net/reports/FBgn0015447.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085657 CG41496 http://flybase.net/reports/FBgn0085657.html FBan0041496 protein_coding_gene 16-Dec-15 2015_12 FBgn0025682 scf supercoiling factor http://flybase.net/reports/FBgn0025682.html FBgn0025546 protein_coding_gene "0005509=calcium ion binding, 0003916=DNA topoisomerase activity" "0045893=positive regulation of transcription, DNA-templated, 0006325=chromatin organization, 0009047=dosage compensation by hyperactivation of X chromosome, 0006265=DNA topological change" "0005703=polytene chromosome puff, 0005700=polytene chromosome, 0005737=cytoplasm, 0012505=endomembrane system, 0005634=nucleus" "CG9148, DNA supercoiling factor, anon-EST:Posey14, CK02682, SCF, DCB-45, BEST:CK02682" "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG9148 16-Dec-15 2015_12 "ENSDARG00000005115(calub),ENSDARG00000045676(calua),ENSDARG00000070006(rcn1),ENSDARG00000037961(rcn3)" WBGene00019760(calu-1) "ENSXETG00000023059(Q6NVM5_XENTR),ENSXETG00000008174(rcn1)" "ENSMUSG00000029767(Calu),ENSMUSG00000005973(Rcn1),ENSMUSG00000019539(Rcn3)" "ENSG00000128595(CALU),ENSG00000049449(RCN1)" embryonic stage -- adult stage " oogenesis stage && adult stage | female , embryonic stage | late , larval stage , embryonic stage | blastoderm " " oocyte

, macrophage

, embryonic/larval fat body

, trachea

, embryonic/larval salivary gland | anterior

, pericardial cell

, embryonic/larval salivary gland | posterior

, embryonic/larval hindgut

, garland cell

" "lethal,male,visible,dominant,homeotic,partially,viable,female,lethal - all die before end of larval stage,recessive,some die during third instar larval stage" "adult abdominal segment 6,male,adult abdominal segment 5,ectopic,polytene chromosome | male" FBgn0267581 CR45921 http://flybase.net/reports/FBgn0267581.html non_protein_coding_gene CR45921 16-Dec-15 2015_12 FBgn0037920 CG14710 http://flybase.net/reports/FBgn0037920.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0003677=DNA binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG14710 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "viable,fertile" FBgn0004099 l(2)60Dg lethal (2) 60Dg http://flybase.net/reports/FBgn0004099.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0016629 E(gl)2E Enhancer of glass 2E http://flybase.net/reports/FBgn0016629.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259673 B0975 http://flybase.net/reports/FBgn0259673.html gene 16-Dec-15 2015_12 "wing,chaeta,ectopic,wing vein L3" FBgn0065174 l(3)SH017 lethal (3) SH017 http://flybase.net/reports/FBgn0065174.html gene l(2)SH3 017 16-Dec-15 2015_12 "lethal,recessive" FBgn0033443 CG1698 http://flybase.net/reports/FBgn0033443.html protein_coding_gene "0017032=potassium:amino acid symporter activity, 0005416=cation:amino acid symporter activity, 0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity" "0044745=amino acid transmembrane import, 0006836=neurotransmitter transport" 0016021=integral component of membrane DmNAT5 IPR000175=Sodium:neurotransmitter symporter CG1698 16-Dec-15 2015_12 viable FBgn0029091 CS-2 Chitin synthase 2 http://flybase.net/reports/FBgn0029091.html FBgn0037145 protein_coding_gene 0004100=chitin synthase activity "Chitin Syn2, chitin-synthase, Chitin Synthase A, DmCS-2, DmeChSA, CG7464, ChSA" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR004835=Chitin synthase" CG7464 16-Dec-15 2015_12 "ENSDARG00000068951(si:ch211-219a15.4),ENSDARG00000068946(si:ch211-264e16.2),ENSDARG00000068947(si:ch211-264e16.1)" "YNL192W(CHS1),YBR038W(CHS2)" viable FBgn0065973 invader3\ORF ORF http://flybase.net/reports/FBgn0065973.html transposable_element_gene 16-Dec-15 2015_12 FBgn0067366 l(2)NC30 lethal (2) NC30 http://flybase.net/reports/FBgn0067366.html gene NC30 16-Dec-15 2015_12 "lethal,recessive" FBgn0060783 l(3)S059913a lethal (3) S059913a http://flybase.net/reports/FBgn0060783.html gene 0599/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0031449 CG31689 http://flybase.net/reports/FBgn0031449.html FBgn0051689 protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" 0043190=ATP-binding cassette (ABC) transporter complex CG9892 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR013525=ABC-2 type transporter" CG31689 16-Dec-15 2015_12 viable FBgn0265163 CR44232 http://flybase.net/reports/FBgn0265163.html non_protein_coding_gene CR44232 16-Dec-15 2015_12 FBgn0267038 CR45482 http://flybase.net/reports/FBgn0267038.html non_protein_coding_gene CR45482 16-Dec-15 2015_12 FBgn0060821 l(3)S052318b lethal (3) S052318b http://flybase.net/reports/FBgn0060821.html gene 0523/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0004934 a(3)48 abnormal abdomen (3) 48 http://flybase.net/reports/FBgn0004934.html gene 16-Dec-15 2015_12 "viable,fertile,visible,maternal effect,recessive,good" "tergite,sternite" FBgn0050380 CG30380 http://flybase.net/reports/FBgn0050380.html protein_coding_gene CG30380 16-Dec-15 2015_12 viable FBgn0085297 CG34268 http://flybase.net/reports/FBgn0085297.html protein_coding_gene CG34268 16-Dec-15 2015_12 FBgn0010630 l(2)06935 lethal (2) 06935 http://flybase.net/reports/FBgn0010630.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031010 CG8028 http://flybase.net/reports/FBgn0031010.html protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "monocarboxylate transporter, MCT" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8028 16-Dec-15 2015_12 viable FBgn0005466 l(1)ts108 lethal (1) ts108 http://flybase.net/reports/FBgn0005466.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0002150 l(2)KE39 lethal (2) KE39 http://flybase.net/reports/FBgn0002150.html gene 16-Dec-15 2015_12 lethal FBgn0005753 l(1)TK308 lethal (1) TK308 http://flybase.net/reports/FBgn0005753.html gene l308 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0027277 l(1)G0199 lethal (1) G0199 http://flybase.net/reports/FBgn0027277.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028868 CG4701 http://flybase.net/reports/FBgn0028868.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" 0005741=mitochondrial outer membrane "DmDM19DC4Z, BG:DS06874.3" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG4701 16-Dec-15 2015_12 ENSDARG00000056609(atad1b) YGR028W(MSP1) WBGene00010557(mspn-1) ENSXETG00000009266(ATAD1) ENSMUSG00000013662(Atad1) ENSG00000138138(ATAD1) DRSC01952 IK -1.732018369 -1.201498119 -1.416515964 -1.144379224 0.060050948 1.918188962 FBgn0035549 CG11346 http://flybase.net/reports/FBgn0035549.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002753 mit(1)3 mitotic 3 http://flybase.net/reports/FBgn0002753.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0004482 l(1)air9 lethal aberrant immune response 9 http://flybase.net/reports/FBgn0004482.html gene "l(1)air[9], air9" 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval lymph gland" FBgn0026866 Gsc::h Gsc::h http://flybase.net/reports/FBgn0026866.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,female" FBgn0067809 anon-N4 anon-N4 http://flybase.net/reports/FBgn0067809.html gene N4 16-Dec-15 2015_12 FBgn0010579 l(2)38EFd lethal (2) 38EFd http://flybase.net/reports/FBgn0010579.html FBgn0025167 gene l(2)04530 16-Dec-15 2015_12 "lethal,recessive" FBgn0043596 E(roDOM)1777 E(roDOM)1777 http://flybase.net/reports/FBgn0043596.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0031970 CG7227 http://flybase.net/reports/FBgn0031970.html protein_coding_gene 0005044=scavenger receptor activity "0007155=cell adhesion, 0006952=defense response" "0016020=membrane, 0005887=integral component of plasma membrane" IPR002159=CD36 antigen CG7227 16-Dec-15 2015_12 viable FBgn0037467 CG1104 http://flybase.net/reports/FBgn0037467.html protein_coding_gene 0012505=endomembrane system IPR018611=E3 UFM1-protein ligase 1 CG1104 16-Dec-15 2015_12 ENSDARG00000007496(zgc:63562) WBGene00015555(C06G3.9) ENSXETG00000001064(KIAA0776) ENSMUSG00000040359(1810074P20Rik) ENSG00000014123(KIAA0776) viable FBgn0040506 ACXE ACXE http://flybase.net/reports/FBgn0040506.html FBgn0032461 protein_coding_gene 0004016=adenylate cyclase activity "0035556=intracellular signal transduction, 0009190=cyclic nucleotide biosynthetic process" 0016021=integral component of membrane "AC, CG17178, DACXE" "IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG17178 16-Dec-15 2015_12 FBgn0001313 kl-2 male fertility factor kl2 http://flybase.net/reports/FBgn0001313.html "FBgn0039968, FBgn0058438, FBan0017866" protein_coding_gene "0005524=ATP binding, 0042623=ATPase activity, coupled, 0003777=microtubule motor activity, 0003774=motor activity" 0007018=microtubule-based movement "0005858=axonemal dynein complex, 0030286=dynein complex, 0005875=microtubule associated complex" "Lms2, 1beta-dynein heavy chain, CG40438, kl2, CG17866, male fertility factor kl-2" "IPR004273=Dynein heavy chain domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR024743=Dynein heavy chain, coiled coil stalk, IPR011704=ATPase, dynein-related, AAA domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR013594=Dynein heavy chain, domain-1" CG17866 16-Dec-15 2015_12 ENSXETG00000008299(DNAH2) ENSMUSG00000005237(Dnahc2) ENSG00000183914(DNAH2) "viable,learning defective,male sterile" "Nebenkern,spermatid,spermatocyte" FBgn0067913 Egfr::kek1 Egfr::kek1 http://flybase.net/reports/FBgn0067913.html engineered_fusion_gene 16-Dec-15 2015_12 visible "egg,dorsal appendage,chorion,eye,ommatidium" FBgn0038767 trem trade embargo http://flybase.net/reports/FBgn0038767.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "0007126=meiotic nuclear division, 0010705=meiotic DNA double-strand break processing involved in reciprocal meiotic recombination, 0010780=meiotic DNA double-strand break formation involved in reciprocal meiotic recombination, 0007131=reciprocal meiotic recombination" "0005634=nucleus, 0000790=nuclear chromatin" "Trade Embargo, CG4413" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4413 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "meiotic cell cycle defective,cold sensitive,viable" DRSC15575 E -0.583437492 0.034892115 -1.574234871 -0.17542329 -0.610415479 -0.025590714 FBgn0020277 lush lush http://flybase.net/reports/FBgn0020277.html protein_coding_gene "0005549=odorant binding, 0035276=ethanol binding, 0035274=diphenyl phthalate binding, 0035275=dibutyl phthalate binding" "0007608=sensory perception of smell, 0007619=courtship behavior, 0042048=olfactory behavior, 0045471=response to ethanol, 0007606=sensory perception of chemical stimulus, 0019236=response to pheromone" 0005576=extracellular region "Obp76a, CG8807, LUSH, obp76a, 76c, 76c(LUSH), 76a, DmelObp76a, Lush" IPR006170=Pheromone/general odorant binding protein CG8807 16-Dec-15 2015_12 "neurophysiology defective,courtship behavior defective,wild-type,smell perception defective,viable,fertile,recessive,neuroanatomy defective" "olfactory receptor neuron,T1 neuron,T2 neuron,pit sensillum T1,pit sensillum T2,adult olfactory receptor neuron Or67d" FBgn0005700 l(1)TK103 lethal (1) TK103 http://flybase.net/reports/FBgn0005700.html gene l103 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0027596 Kank Kank http://flybase.net/reports/FBgn0027596.html FBgn0043818 protein_coding_gene 0051010=microtubule plus-end binding 0048812=neuron projection morphogenesis "0005927=muscle tendon junction, 0005737=cytoplasm, 0005634=nucleus, 0035371=microtubule plus-end" "CG10249, BcDNA:GH03482, BEST:GH19041, kank" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR021939=Kank N-terminal motif" CG10249 16-Dec-15 2015_12 "ENSDARG00000060102(si:dkey-146l2.1),ENSDARG00000060584(si:dkey-226m8.9)" WBGene00006882(vab-19) "ENSXETG00000021895(KANK3),ENSXETG00000009344(KANK2)" "ENSMUSG00000032702(Kank1),ENSMUSG00000032194(Kank2)" "ENSG00000107104(KANK1),ENSG00000197256(KANK2)" viable FBgn0034122 CG15711 http://flybase.net/reports/FBgn0034122.html protein_coding_gene CG15711 16-Dec-15 2015_12 viable FBgn0015895 anon-95EFa anon-95EFa http://flybase.net/reports/FBgn0015895.html gene unnamed 16-Dec-15 2015_12 FBgn0259817 SteXh:CG42398 SteXh:CG42398 http://flybase.net/reports/FBgn0259817.html protein_coding_gene 0019887=protein kinase regulator activity 0005956=protein kinase CK2 complex "RR41752, CG42398" "IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR000704=Casein kinase II, regulatory subunit" CG42398 16-Dec-15 2015_12 FBgn0083244 EP1200 EP1200 http://flybase.net/reports/FBgn0083244.html gene 16-Dec-15 2015_12 FBgn0085610 CG41316 http://flybase.net/reports/FBgn0085610.html FBan0041316 protein_coding_gene 16-Dec-15 2015_12 FBgn0045063 fdl fused lobes http://flybase.net/reports/FBgn0045063.html "FBgn0021791, FBgn0033745" protein_coding_gene "0004563=beta-N-acetylhexosaminidase activity, 0016231=beta-N-acetylglucosaminidase activity, 0032428=beta-N-acetylgalactosaminidase activity" "0006032=chitin catabolic process, 0007420=brain development, 0006491=N-glycan processing, 0016063=rhodopsin biosynthetic process, 0006517=protein deglycosylation" "0005783=endoplasmic reticulum, 0005770=late endosome, 0005886=plasma membrane, 0005794=Golgi apparatus" "Fdl, l(2)k17040, FDL, Fused Lobes, CG8824" "IPR017853=Glycoside hydrolase superfamily, IPR029018=Chitobiase/beta-hexosaminidase domain 2-like, IPR025705=Beta-hexosaminidase, IPR029019=Beta-hexosaminidase, eukaryotic type, N-terminal, IPR013781=Glycoside hydrolase, catalytic domain, IPR015883=Glycoside hydrolase family 20, catalytic domain" CG8824 16-Dec-15 2015_12 "ENSDARG00000034368(hexa),ENSDARG00000052113(zgc:112084)" WBGene00020509(hex-1) ENSXETG00000005075(HEXB) "ENSMUSG00000025232(Hexa),ENSMUSG00000021665(Hexb)" "ENSG00000213614(HEXA),ENSG00000049860(HEXB)" "lethal,recessive,viable,neuroanatomy defective,cell lethalcell lethal,somatic clone" "protocerebral bridge,mushroom body beta-lobe" FBgn0037295 dpr16 defective proboscis extension response 16 http://flybase.net/reports/FBgn0037295.html protein_coding_gene 0007606=sensory perception of chemical stimulus "dpr16, CT34444, CG12591, Dpr-16, mdcds_51595, Dpr16" "IPR007110=Immunoglobulin-like domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG12591 16-Dec-15 2015_12 "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" "ENSMUSG00000054793(Cadm4),ENSMUSG00000032076(Cadm1),ENSMUSG00000064115(Cadm2),ENSMUSG00000005338(Cadm3)" "ENSG00000105767(CADM4),ENSG00000182985(CADM1),ENSG00000175161(CADM2),ENSG00000162706(CADM3)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038571 CG7215 http://flybase.net/reports/FBgn0038571.html "FBgn0052920, FBtr0083620, FBpp0083040, FBtr0083621, FBpp0083041, FBtr0083622, FBpp0083042" protein_coding_gene CG32920 "IPR029071=Ubiquitin-related domain, IPR000626=Ubiquitin domain" CG7215 16-Dec-15 2015_12 ENSDARG00000007359(zgc:56596) ENSXETG00000007175() "ENSMUSG00000015290(Ubl4),ENSMUSG00000055891(Ubl4b)" "ENSG00000102178(UBL4A),ENSG00000186150(UBL4B)" FBgn0015408 l(1)12Bc lethal (1) 12Bc http://flybase.net/reports/FBgn0015408.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036500 CG7275 http://flybase.net/reports/FBgn0036500.html protein_coding_gene "0022008=neurogenesis, 0006909=phagocytosis" "IPR019775=WD40 repeat, conserved site, IPR007287=Sof1-like protein, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG7275 16-Dec-15 2015_12 ENSDARG00000002267(dcaf13) YLL011W(SOF1) WBGene00022742(ZK430.7) ENSXETG00000004092(BC067929.1) ENSMUSG00000022300(Dcaf13) ENSG00000164934(DCAF13) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC10796 K -0.402897776 -0.030676213 0.835117667 0.021172666 -1.515904101 -0.301688977 FBgn0033902 Tango7 Transport and Golgi organization 7 http://flybase.net/reports/FBgn0033902.html "FBgn0027672, FBgn0063815" protein_coding_gene 0003743=translation initiation factor activity "0009306=protein secretion, 2001233=regulation of apoptotic signaling pathway, 0097202=activation of cysteine-type endopeptidase activity, 2001272=positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis, 0007291=sperm individualization, 0007030=Golgi organization, 0048812=neuron projection morphogenesis" "0070865=investment cone, 0005829=cytosol, 0005852=eukaryotic translation initiation factor 3 complex, 0005875=microtubule associated complex, 0005794=Golgi apparatus, 0043293=apoptosome" "TANGO7, anon-EST:Posey67, tango7, Tango 7, Tng7, anon-EST:Posey76, CG8309, eIF3M, eIF3m" "IPR003607=HD/PDEase domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR027528=Eukaryotic translation initiation factor 3 subunit M, IPR000717=Proteasome component (PCI) domain" CG8309 16-Dec-15 2015_12 ENSDARG00000013931(eif3m) WBGene00019543(cif-1) ENSXETG00000008167(ga17) ENSMUSG00000027170(Eif3m) ENSG00000149100(EIF3M) "viable,male sterile,visible,partially lethal - majority live,short lived,lethal - all die before end of first instar larval stage" "wing,cystic bulge,investment cone" DRSC26908 IEK -1.692700655 -1.572819397 -1.290113461 -2.527817574 0.138779391 2.84422948 FBgn0026606 Act79B::Act88F Act79B::Act88F http://flybase.net/reports/FBgn0026606.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0035025 uri unconventional prefoldin RPB5 interactor http://flybase.net/reports/FBgn0035025.html protein_coding_gene 0019212=phosphatase inhibitor activity 0007283=spermatogenesis "0005737=cytoplasm, 0005700=polytene chromosome" "dURI, ori, origami, CG11416" "IPR009053=Prefoldin, IPR004127=Prefoldin alpha-like" CG11416 16-Dec-15 2015_12 ENSDARG00000026664(zgc:110109) ENSXETG00000012924(C19orf2) ENSMUSG00000030421(C80913) ENSG00000105176(C19orf2) "visible,viable,fertile,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" "wing,testis,ovary,mesothoracic tergum" DRSC04111 IE -0.110019592 -3.651999484 -0.272674164 -2.206205808 -1.126885177 -1.015201786 FBgn0025935 fl(1)35 female lethal (1) 35 http://flybase.net/reports/FBgn0025935.html gene "female lethal-35, fl-35" 16-Dec-15 2015_12 "viable,male,female,reduced,female fertile" FBgn0053121 Spn28Db Serpin 28Db http://flybase.net/reports/FBgn0053121.html FBgn0031964 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "CG33121, CG12318" "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG33121 16-Dec-15 2015_12 viable FBgn0051807 CG31807 http://flybase.net/reports/FBgn0051807.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination 0005634=nucleus "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG31807 16-Dec-15 2015_12 viable FBgn0022197 l(2)k04810 lethal (2) k04810 http://flybase.net/reports/FBgn0022197.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0028654 anon-47Eb anon-47Eb http://flybase.net/reports/FBgn0028654.html gene 5A1 16-Dec-15 2015_12 FBgn0034437 CG10051 http://flybase.net/reports/FBgn0034437.html protein_coding_gene IPR007484=Peptidase M28 CG10051 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) FBgn0002079 l(2)49Fh lethal (2) 49Fh http://flybase.net/reports/FBgn0002079.html gene "l(2)vr13, vr13, vr-13" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,dominant" FBgn0084075 l(3)S133117 l(3)S133117 http://flybase.net/reports/FBgn0084075.html gene 16-Dec-15 2015_12 FBgn0025760 l(3)93DFb lethal (3) 93DFb http://flybase.net/reports/FBgn0025760.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0051141 CG31141 http://flybase.net/reports/FBgn0051141.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane IPR002076=ELO family CG31141 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0011170 l(1)291-5 lethal (1) 291-5 http://flybase.net/reports/FBgn0011170.html FBgn0010199 gene 291-5 16-Dec-15 2015_12 "lethal,recessive" FBgn0044444 GRT-G1-element\RTase RTase http://flybase.net/reports/FBgn0044444.html transposable_element_gene 16-Dec-15 2015_12 FBgn0067042 V8 V8 http://flybase.net/reports/FBgn0067042.html gene 16-Dec-15 2015_12 "eye color defective,lethal,viable" pigment cell FBgn0038470 CG18213 http://flybase.net/reports/FBgn0038470.html protein_coding_gene "IPR002893=Zinc finger, MYND-type" CG18213 16-Dec-15 2015_12 viable FBgn0005246 l(3)R159 lethal of Roberts 159 http://flybase.net/reports/FBgn0005246.html gene l(3)B159 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0262082 m::tyn miniature::trynity http://flybase.net/reports/FBgn0262082.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0032658 CG5681 http://flybase.net/reports/FBgn0032658.html protein_coding_gene CG5681 16-Dec-15 2015_12 viable FBgn0260284 GSd425 http://flybase.net/reports/FBgn0260284.html gene 16-Dec-15 2015_12 lethal FBgn0031110 Obp19b Odorant-binding protein 19b http://flybase.net/reports/FBgn0031110.html FBgn0044641 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "anon-WO0140519.23, 19b, CG1670, o19b, DmelObp19b" IPR006170=Pheromone/general odorant binding protein CG1670 16-Dec-15 2015_12 viable FBgn0023429 l(3)98Fa lethal (3) 98Fa http://flybase.net/reports/FBgn0023429.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0030997 CG7990 http://flybase.net/reports/FBgn0030997.html protein_coding_gene IPR019402=Frag1/DRAM/Sfk1 CG7990 16-Dec-15 2015_12 "viable,fertile" FBgn0042146 CG18823 http://flybase.net/reports/FBgn0042146.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG18823 16-Dec-15 2015_12 viable FBgn0034133 CG7813 http://flybase.net/reports/FBgn0034133.html protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" 0015986=ATP synthesis coupled proton transport "0005753=mitochondrial proton-transporting ATP synthase complex, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "IPR008689=ATPase, F0 complex, subunit D, mitochondrial" CG7813 16-Dec-15 2015_12 viable FBgn0060456 l(3)S118602a lethal (3) S118602a http://flybase.net/reports/FBgn0060456.html gene 1186/02 16-Dec-15 2015_12 lethal FBgn0000344 compressed compressed http://flybase.net/reports/FBgn0000344.html gene com 16-Dec-15 2015_12 "visible,viable,poor,fertile" "adult head,eye,vibrissae,arista,humerus,wing" FBgn0034033 CG8204 http://flybase.net/reports/FBgn0034033.html FBgn0063714 protein_coding_gene BcDNA:AT23078 "IPR007529=Zinc finger, HIT-type" CG8204 16-Dec-15 2015_12 ENSDARG00000023950(LOC100332660) YJR055W(HIT1) ENSXETG00000025713(trip3) ENSMUSG00000020526(Znhit3) ENSG00000108278(ZNHIT3) FBgn0053487 CR33487 http://flybase.net/reports/FBgn0053487.html pseudogene_attribute CG33487 CR33487 16-Dec-15 2015_12 "ENSDARG00000053593(LOC100329372),ENSDARG00000013335(LOC100333447)" FBgn0267629 CR45967 http://flybase.net/reports/FBgn0267629.html non_protein_coding_gene CR45967 16-Dec-15 2015_12 FBgn0038860 Ice2 Interacts with the C terminus of ELL 1 http://flybase.net/reports/FBgn0038860.html protein_coding_gene 0032783=ELL-EAF complex CG10825 "IPR019535=Little elongation complex subunit 2 , C-terminal" CG10825 16-Dec-15 2015_12 "partially lethal - majority die,visible" trichogen cell DRSC14268 E -0.178072484 -0.41790253 -1.719977236 0.17463945 0.177733329 0.21193317 FBgn0005350 Spread Spread http://flybase.net/reports/FBgn0005350.html gene Spr 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority live,male sterile,female fertile" wing FBgn0053229 CG33229 http://flybase.net/reports/FBgn0053229.html "FBgn0035114, FBgn0052492" protein_coding_gene "CG16971, CG32492" CG33229 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum DRSC08497 I -1.53635951 0.120109057 -0.561526714 0.668348251 0.34529911 -0.046386457 FBgn0267190 CR45630 http://flybase.net/reports/FBgn0267190.html non_protein_coding_gene Mgn4221 CR45630 16-Dec-15 2015_12 FBgn0060549 l(3)S098513b lethal (3) S098513b http://flybase.net/reports/FBgn0060549.html gene 0985/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0039782 CG15539 http://flybase.net/reports/FBgn0039782.html protein_coding_gene "0005506=iron ion binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" CG15539-NE4 "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG15539 16-Dec-15 2015_12 viable FBgn0262022 CG42833 http://flybase.net/reports/FBgn0262022.html protein_coding_gene CG42833 16-Dec-15 2015_12 FBgn0029986 CG15332 http://flybase.net/reports/FBgn0029986.html protein_coding_gene IPR006610=Domain of unknown function DM7 CG15332 16-Dec-15 2015_12 "viable,fertile" FBgn0015254 M(2)126 M(2)126 http://flybase.net/reports/FBgn0015254.html gene 16-Dec-15 2015_12 "visible,dominant,Minute" FBgn0259291 C446 http://flybase.net/reports/FBgn0259291.html gene 16-Dec-15 2015_12 visible wing FBgn0069082 sirio sirio http://flybase.net/reports/FBgn0069082.html gene 16-Dec-15 2015_12 male sterile spermatocyte FBgn0267215 CR45655 http://flybase.net/reports/FBgn0267215.html non_protein_coding_gene CR45655 16-Dec-15 2015_12 FBgn0044024 PK4 Pocket 4 http://flybase.net/reports/FBgn0044024.html gene 16-Dec-15 2015_12 FBgn0052006 CG32006 http://flybase.net/reports/FBgn0052006.html FBgn0062441 protein_coding_gene "0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0045787=positive regulation of cell cycle, 0035058=nonmotile primary cilium assembly, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0016199=axon midline choice point recognition, 0007380=specification of segmental identity, head, 0002052=positive regulation of neuroblast proliferation, 0009888=tissue development, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007346=regulation of mitotic cell cycle, 0045665=negative regulation of neuron differentiation, 0009953=dorsal/ventral pattern formation, 0009792=embryo development ending in birth or egg hatching, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048665=neuron fate specification" "0005667=transcription factor complex, 0005634=nucleus" "BcDNA:RE51913, DmCg32006" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain" CG32006 16-Dec-15 2015_12 viable FBgn0003067 Pepck Phosphoenolpyruvate carboxykinase http://flybase.net/reports/FBgn0003067.html protein_coding_gene "0005525=GTP binding, 0004613=phosphoenolpyruvate carboxykinase (GTP) activity" 0006094=gluconeogenesis 0005739=mitochondrion "143299_at, Phosphoenolpyruvate-carboxykinase, phosphoenolpyruvate carboxykinase, Dromel_CG17725_FBtr0086701_pepck_mORF, pepck, phosphoenolpyruvate carboxy kinase, dPEPCK, phosphoenol pyruvate carboxykinase, CG17725, CG10924, PEPCK" "IPR018091=Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site, IPR013035=Phosphoenolpyruvate carboxykinase, C-terminal, IPR008209=Phosphoenolpyruvate carboxykinase, GTP-utilising, IPR008210=Phosphoenolpyruvate carboxykinase, N-terminal" CG17725 16-Dec-15 2015_12 "ENSDARG00000013522(pck1),ENSDARG00000020956(pck2)" "WBGene00011232(R11A5.4),WBGene00021043(W05G11.6)" "ENSXETG00000014608(pck2),ENSXETG00000011266(pck1)" "ENSMUSG00000040618(Pck2),ENSMUSG00000027513(Pck1)" "ENSG00000100889(PCK2),ENSG00000124253(PCK1)" " larval stage | first instar , larval stage | second instar "

late viable FBgn0264470 CR43878 http://flybase.net/reports/FBgn0264470.html non_protein_coding_gene CR43878 16-Dec-15 2015_12 FBgn0004673 dlg2 discs large 2 http://flybase.net/reports/FBgn0004673.html gene l(1)d.lg.-2 16-Dec-15 2015_12 embryonic/larval brain FBgn0040323 GNBP1 Gram-negative bacteria binding protein 1 http://flybase.net/reports/FBgn0040323.html FBgn0036803 protein_coding_gene "0001530=lipopolysaccharide binding, 0030247=polysaccharide binding, 0005515=protein binding, 0052736=beta-glucanase activity, 0042834=peptidoglycan binding, 0008329=signaling pattern recognition receptor activity, 0001872=(1->3)-beta-D-glucan binding" "0050832=defense response to fungus, 0005975=carbohydrate metabolic process, 0009253=peptidoglycan catabolic process, 0050829=defense response to Gram-negative bacterium, 0050830=defense response to Gram-positive bacterium, 0006955=immune response, 0002758=innate immune response-activating signal transduction, 0045087=innate immune response" "0005576=extracellular region, 0046658=anchored component of plasma membrane" "GNBP 1, glucan-binding protein 1, DGNBP1, GNBP, osiris, gram-negative binding protein 1, GNBP-1, CG6895, DGNBP-1" "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR000757=Glycoside hydrolase, family 16" CG6895 16-Dec-15 2015_12 "immune response defective,viable" FBgn0050239 tRNA:CR30239 transfer RNA:CR30239 http://flybase.net/reports/FBgn0050239.html FBgn0011847 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:Glu, transfer RNA:glu4:53A, CR30239, chr2R.trna25-GluCTC, tRNA:glu4:53A, tRNA:E4:53A" CR30239 16-Dec-15 2015_12 FBgn0032482 Pect Phosphoethanolamine cytidylyltransferase http://flybase.net/reports/FBgn0032482.html protein_coding_gene 0004306=ethanolamine-phosphate cytidylyltransferase activity "0009058=biosynthetic process, 0042439=ethanolamine-containing compound metabolic process" "phosphoethanolamine cytidylyltransferase;, pect, CG5547, PECT" "IPR004821=Cytidyltransferase-like domain, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG5547 16-Dec-15 2015_12 ENSDARG00000043003(pcyt2) YGR007W(MUQ1) WBGene00021352(Y37E3.11) ENSXETG00000005389(pcyt2) ENSMUSG00000025137(Pcyt2) "ENSG00000185813(PCYT2),ENSG00000218375" viable adult heart FBgn0262355 CR43053 http://flybase.net/reports/FBgn0262355.html non_protein_coding_gene "lincRNA.164, CG43053" CR43053 16-Dec-15 2015_12 FBgn0039939 CG11231 http://flybase.net/reports/FBgn0039939.html protein_coding_gene CG11231 16-Dec-15 2015_12 viable FBgn0011799 l(3)rJ880 lethal (3) rJ880 http://flybase.net/reports/FBgn0011799.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027116 mei-P23 mei-P23 http://flybase.net/reports/FBgn0027116.html gene 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0039258 ë_4GalT7 ë_-4-galactosyltransferase 7 http://flybase.net/reports/FBgn0039258.html protein_coding_gene "0046525=xylosylprotein 4-beta-galactosyltransferase activity, 0008378=galactosyltransferase activity, 0046872=metal ion binding" "0015012=heparan sulfate proteoglycan biosynthetic process, 0006491=N-glycan processing, 0006024=glycosaminoglycan biosynthetic process, 0030206=chondroitin sulfate biosynthetic process, 0030166=proteoglycan biosynthetic process" "0016021=integral component of membrane, 0005794=Golgi apparatus" "CG11780, dGAGbeta4GalTI, dbeta4GalTI, beta4Gal-T7, GalT, betaGalT7, Dbeta4GalT7, dbeta4GalT7, GalTI, beta-1,-4-galactosyltransferase, Galactosyltransferase I, glycosaminoglycan galactosyltransferase I, beta1,4-Galactosyltransferase-7, beta4GalTI" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR027995=Galactosyltransferase, N-terminal, IPR003859=Beta-1,4-galactosyltransferase, IPR027791=Galactosyltransferase, C-terminal" CG11780 16-Dec-15 2015_12 ENSDARG00000021899(b4galt7) WBGene00005021(sqv-3) ENSXETG00000006736(B4GALT7) ENSMUSG00000021504(B4galt7) ENSG00000027847(B4GALT7) embryonic stage -- adult stage "visible,lethal,viable" "wing,posterior compartment,eye,ommatidium,interommatidial bristle,dorsal compartment,wing vein L2,leg,distal" FBgn0016119 ATPsynCF6 "ATP synthase, coupling factor 6" http://flybase.net/reports/FBgn0016119.html FBgn0064843 protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0046331=lateral inhibition, 0015986=ATP synthesis coupled proton transport, 0015992=proton transport" "0005756=mitochondrial proton-transporting ATP synthase, central stalk, 0005739=mitochondrion, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATPase coupling-factor 6, BcDNA:RH08870, ATPase coupling factor 6, ATPR, ATPsyn-Cf6, ATP synthase coupling factor 6, F0/F1 ATP synthase Coupling factor 6, ATP synthase Coupling factor 6, CG4412" "IPR016349=ATPase, F0 complex, subunit F6, mitochondrial subgroup, IPR008387=ATPase, F0 complex, subunit F6, mitochondrial" CG4412 16-Dec-15 2015_12 ENSDARG00000014313(atp5j) WBGene00020275(atp-4) ENSXETG00000013610(ATP5J) ENSMUSG00000022890(Atp5j) ENSG00000154723(ATP5J) "visible,partially lethal - majority die,some die during pupal stage" chaeta FBgn0017426 anon-68Eb anon-68Eb http://flybase.net/reports/FBgn0017426.html gene T2 16-Dec-15 2015_12 FBgn0264953 Piezo Piezo http://flybase.net/reports/FBgn0264953.html "FBgn0031993, FBgn0025998, FBgn0013442, FBgn0011820, FBgn0031994, FBgn0051608, FBgn0063629" protein_coding_gene 0008381=mechanically-gated ion channel activity "0007638=mechanosensory behavior, 0071260=cellular response to mechanical stimulus" "0005886=plasma membrane, 0016021=integral component of membrane" "fos-related gene at 28F, unnamed, Dmpiezo, OrfKD, clone 1.32, CG44122, DmPiezo, CG18103, anon-EST:Liang-1.32, CG31608, fos500, fos28F, CG8486" "IPR027272=Piezo family, IPR031334=Piezo non-specific cation channel, R-Ras-binding domain" CG44122 16-Dec-15 2015_12 WBGene00011862(T20D3.11) ENSXETG00000011253(FAM38A) "ENSMUSG00000014444,ENSMUSG00000041482(Fam38b)" ENSG00000103335(FAM38A) FBgn0000060 agn agnostic http://flybase.net/reports/FBgn0000060.html gene 0048477=oogenesis "ts398, l(1)11Af, ag" 16-Dec-15 2015_12 "lethal,heat sensitive,learning defective,mitotic cell cycle defective,locomotor behavior defective,female,smell perception defective" "nurse cell,heat sensitive,egg chamber,follicle cell,nodulus" FBgn0027938 trt trt http://flybase.net/reports/FBgn0027938.html gene 0030178=negative regulation of Wnt signaling pathway 0005634=nucleus tartaruga 16-Dec-15 2015_12 FBgn0266446 CG45076 http://flybase.net/reports/FBgn0266446.html "FBgn0020439, FBgn0063173" protein_coding_gene CG6544 CG45076 16-Dec-15 2015_12 "viable,fertile,lethal" FBgn0003487 spot spot http://flybase.net/reports/FBgn0003487.html gene 16-Dec-15 2015_12 head FBgn0086051 snoRNA:Me28S-U2134a http://flybase.net/reports/FBgn0086051.html snoRNA_gene "DmSnR62, Dm_28S.018, DmSnR62b, Dm_28S.018a, CR34680, Me28S-U2134a(DmSnR62), Me28S-Um2134a, DmSnR62a" CR34680 16-Dec-15 2015_12 FBgn0005239 l(3)R73 lethal of Roberts 73 http://flybase.net/reports/FBgn0005239.html gene l(3)B73 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0040714 CG15391 http://flybase.net/reports/FBgn0040714.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262743 Fs(2)Ket Female sterile (2) Ketel http://flybase.net/reports/FBgn0262743.html "FBgn0000986, FBgn0000984, FBgn0000989, FBgn0004812, FBgn0005392, FBgn0086557" protein_coding_gene "0008320=protein transmembrane transporter activity, 0008536=Ran GTPase binding" "0051533=positive regulation of NFAT protein import into nucleus, 0006606=protein import into nucleus, 0007015=actin filament organization, 0008360=regulation of cell shape, 0007067=mitotic nuclear division, 0000059=protein import into nucleus, docking, 0006607=NLS-bearing protein import into nucleus, 0007304=chorion-containing eggshell formation" "0005654=nucleoplasm, 0043186=P granule, 0005643=nuclear pore, 0005875=microtubule associated complex, 0005737=cytoplasm, 0005635=nuclear envelope, 0005811=lipid particle" "Importin-beta, female sterile(2)lto2, Kpnb1, ketel, dKap-beta, impbeta, fs(2)lo-B, fs(2) Ketel, Fs(2)Sz6, Hon, Importin beta, imp-beta, fs(2)Ket, importin beta1, 38E.11, importin beta, Female sterile (2) ketel, Impbeta, CG2637, importin-beta, fs(2)lto2, Ketel, IMPbeta1, fs(2)ltoHD43, mRNA-like ncRNA in embryogenesis 26, DImportin-beta, Fs(2)Sz7, Fs(2)ket, kettle, MRE26, Ket, Fs(2)Hon, Hont" "IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain, IPR027140=Importin subunit beta-1, IPR011989=Armadillo-like helical, IPR021133=HEAT, type 2" CG2637 16-Dec-15 2015_12 ENSDARG00000008680(kpnb1) YLR347C(KAP95) WBGene00002075(imb-1) ENSMUSG00000001440(Kpnb1) ENSG00000108424(KPNB1) DRSC03328 IE -2.383368857 -3.573191205 -0.065656654 -2.966234443 -0.665249481 0.394128967 FBgn0040854 CG15222 http://flybase.net/reports/FBgn0040854.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005358 Su(wa)B1 Suppressor of white-apricot B on 1 http://flybase.net/reports/FBgn0005358.html gene unnamed 16-Dec-15 2015_12 eye color defective FBgn0016766 anon-17Cc anon-17Cc http://flybase.net/reports/FBgn0016766.html gene "Transcription unit C3, C3" 16-Dec-15 2015_12 " embryonic stage | early , adult stage | female " FBgn0025765 l(3)89De lethal (3) 89De http://flybase.net/reports/FBgn0025765.html gene l(3)M188 16-Dec-15 2015_12 "lethal,recessive" FBgn0026064 KP78a KP78a http://flybase.net/reports/FBgn0026064.html FBgn0022392 protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "KP78A, Kp78A, CG6715" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG6715 16-Dec-15 2015_12 YER129W(SAK1) viable FBgn0003449 snf sans fille http://flybase.net/reports/FBgn0003449.html FBgn0005667 protein_coding_gene "0042802=identical protein binding, 0030619=U1 snRNA binding, 0008266=poly(U) RNA binding, 0035614=snRNA stem-loop binding, 0097158=pre-mRNA intronic pyrimidine-rich binding, 0030620=U2 snRNA binding, 0000166=nucleotide binding, 0003729=mRNA binding, 0005515=protein binding" "0000398=mRNA splicing, via spliceosome, 0007539=primary sex determination, soma, 0008380=RNA splicing, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0048477=oogenesis, 0019099=female germ-line sex determination" "0071011=precatalytic spliceosome, 0030529=ribonucleoprotein complex, 0043234=protein complex, 0005692=U11 snRNP, 0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex, 0005685=U1 snRNP, 0005681=spliceosomal complex, 0005686=U2 snRNP, 0071013=catalytic step 2 spliceosome" "snRNP B'', Snf, U1-A, CG4528, fs(1)A16121, unnamed, fs(1)A1621, fs(1)1621, U2 snRNP, Sans fille, D25, Sans-fille, SNF/D25, U2 snRNP B'' protein, simply not fertile, splicing necessary factor, liz, SNF, snf1621" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR024888=U1 small nuclear ribonucleoprotein A/U2 small nuclear ribonucleoprotein B'', IPR000504=RNA recognition motif domain" CG4528 16-Dec-15 2015_12 ENSDARG00000039424 WBGene00004386(rnp-3) ENSXETG00000003550(snrbp2) ENSMUSG00000008333(Snrpb2) ENSG00000125870(SNRPB2) " adult stage | female , adult stage | male " embryonic stage -- adult stage "female sterile,dominant,female fertile,recessive,tumorigenic,wild-type,viable,male fertile,lethal,male,maternal effect,female sterile germline-dependent,lethal - all die before end of embryonic stage,some die during embryonic stage" "ovary,egg chamber,germarium,prothoracic leg & macrochaeta | female" DRSC18835 E 0.225311399 0.597857856 2.412195221 1.737390191 0.077493744 -0.662613765 FBgn0265789 CR44578 http://flybase.net/reports/FBgn0265789.html non_protein_coding_gene CR44578 16-Dec-15 2015_12 FBgn0046658 anon-38C.51 anon-38C.51 http://flybase.net/reports/FBgn0046658.html gene 38C.51 16-Dec-15 2015_12 FBgn0032650 CG7094 http://flybase.net/reports/FBgn0032650.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation 0005737=cytoplasm CKIa-like "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR008271=Serine/threonine-protein kinase, active site" CG7094 16-Dec-15 2015_12 viable FBgn0013640 lgm lightminded http://flybase.net/reports/FBgn0013640.html gene 16-Dec-15 2015_12 FBgn0032187 CG4839 http://flybase.net/reports/FBgn0032187.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004692=cGMP-dependent protein kinase activity" 0006468=protein phosphorylation "0005737=cytoplasm, 0005886=plasma membrane" PKG-like "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR018490=Cyclic nucleotide-binding-like, IPR000961=AGC-kinase, C-terminal, IPR000595=Cyclic nucleotide-binding domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR014710=RmlC-like jelly roll fold, IPR000719=Protein kinase domain, IPR018488=Cyclic nucleotide-binding, conserved site" CG4839 16-Dec-15 2015_12 viable FBgn0005699 l(1)TK102 lethal (1) TK102 http://flybase.net/reports/FBgn0005699.html gene l102 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0265851 CR44640 http://flybase.net/reports/FBgn0265851.html non_protein_coding_gene CR44640 16-Dec-15 2015_12 FBgn0028393 anon-50ABa anon-50ABa http://flybase.net/reports/FBgn0028393.html gene A 16-Dec-15 2015_12 FBgn0031118 RhoGAP19D Rho GTPase activating protein at 19D http://flybase.net/reports/FBgn0031118.html protein_coding_gene 0005096=GTPase activator activity "0007266=Rho protein signal transduction, 0007480=imaginal disc-derived leg morphogenesis" "1412, RhoGAP19D, CG1412" "IPR001478=PDZ domain, IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG1412 16-Dec-15 2015_12 ENSDARG00000052950 WBGene00015418(pac-1) "ENSXETG00000005905(ARHGAP21),ENSXETG00000014740()" "ENSMUSG00000036591(Arhgap21),ENSMUSG00000049807(Arhgap23)" ENSG00000107863(ARHGAP21) "partially lethal - majority die,visible" "heart primordium,trichogen cell" DRSC20499 IE 1.553562126 2.010733474 2.561704308 -1.092613116 0.035227209 0.347061147 FBgn0039190 CG5762 http://flybase.net/reports/FBgn0039190.html "FBgn0044551, FBgn0046305" protein_coding_gene "BEST:GH05452, anon-WO0140519.76" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG5762 16-Dec-15 2015_12 viable FBgn0041743 l(2)44Fk lethal (2) 44Fk http://flybase.net/reports/FBgn0041743.html gene l(2)44Fh 16-Dec-15 2015_12 "lethal,recessive" FBgn0266159 CR44865 http://flybase.net/reports/FBgn0266159.html non_protein_coding_gene CR44865 16-Dec-15 2015_12 FBgn0267794 CR43174 http://flybase.net/reports/FBgn0267794.html "FBgn0262793, FBgn0262792" non_protein_coding_gene "CR43173, CG43174, CG43173, mdcds_28406" CR43174 16-Dec-15 2015_12 FBgn0034989 CG3356 http://flybase.net/reports/FBgn0034989.html protein_coding_gene "0031624=ubiquitin conjugating enzyme binding, 0004842=ubiquitin-protein transferase activity" "0000209=protein polyubiquitination, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process" "0005634=nucleus, 0005737=cytoplasm" "IPR000569=HECT domain, IPR000048=IQ motif, EF-hand binding site" CG3356 16-Dec-15 2015_12 ENSDARG00000035978(ube3c) YGL141W(HUL5) WBGene00008429(D2085.4) ENSXETG00000021620(UBE3C) ENSMUSG00000039000(Ube3c) ENSG00000009335(UBE3C) viable FBgn0085604 CG41298 http://flybase.net/reports/FBgn0085604.html FBan0041298 protein_coding_gene 16-Dec-15 2015_12 FBgn0266407 CR45047 http://flybase.net/reports/FBgn0266407.html non_protein_coding_gene CR45047 16-Dec-15 2015_12 FBgn0028153 l(3)S042622 lethal (3) S042622 http://flybase.net/reports/FBgn0028153.html gene 0426/22 16-Dec-15 2015_12 "lethal,recessive" FBgn0266409 CG45049 http://flybase.net/reports/FBgn0266409.html "FBgn0040587, FBgn0039014" protein_coding_gene "0007163=establishment or maintenance of cell polarity, 0060857=establishment of glial blood-brain barrier" "0016021=integral component of membrane, 0005918=septate junction" "CG17618, CG6982" "IPR004031=PMP-22/EMP/MP20/Claudin superfamily, IPR015664=P53-induced protein" CG45049 16-Dec-15 2015_12 "ENSDARG00000057322(zgc:63990),ENSDARG00000063572(perp)" WBGene00006875(vab-9) ENSXETG00000027069(TM47_XENTR) ENSMUSG00000025666(Tmem47) "ENSG00000147027(TMEM47),ENSG00000112378(PERP)" FBgn0029795 CG15773 http://flybase.net/reports/FBgn0029795.html protein_coding_gene IPR008472=Domain of unknown function DUF753 CG15773 16-Dec-15 2015_12 FBgn0264003 mir-5613 mir-5613 stem loop http://flybase.net/reports/FBgn0264003.html gene CR43746 16-Dec-15 2015_12 FBgn0260870 CG42580 http://flybase.net/reports/FBgn0260870.html protein_coding_gene HDC19854 CG42580 16-Dec-15 2015_12 FBgn0260222 CG42496 http://flybase.net/reports/FBgn0260222.html protein_coding_gene Dromel_CG30290_FBtr0071672_cx9c_uORF IPR010625=CHCH CG42496 16-Dec-15 2015_12 YLL018C-A(COX19) WBGene00009745(F45H11.5) ENSMUSG00000045438(Cox19) ENSG00000189201 FBgn0003215 rdb reddish brown http://flybase.net/reports/FBgn0003215.html gene 16-Dec-15 2015_12 "male sterile,visible,viable,male,reduced,recessive,eye color defective" "pigment cell,wing" FBgn0266918 CG32486 http://flybase.net/reports/FBgn0266918.html "FBgn0052486, FBgn0035394, FBgn0035395, FBgn0062132, FBgn0065142" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination "CG14954, l(2)SH3 095, l(3)SH095, lethal (3) SH095, anon-WO0118547.267, CG16745" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR001293=Zinc finger, TRAF-type, IPR008974=TRAF-like, IPR013323=SIAH-type domain" CG32486 16-Dec-15 2015_12 ENSDARG00000061057(zgc:153061) ENSXETG00000009612(CYHR1) ENSMUSG00000053929(Cyhr1) ENSG00000204763 FBgn0052302 CG32302 http://flybase.net/reports/FBgn0052302.html FBgn0035326 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG13805 IPR002557=Chitin binding domain CG32302 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0003941 RpL40 Ribosomal protein L40 http://flybase.net/reports/FBgn0003941.html FBgn0061410 protein_coding_gene "0003735=structural constituent of ribosome, 0031386=protein tag" "0016567=protein ubiquitination, 0006412=translation, 0006464=cellular protein modification process, 0006511=ubiquitin-dependent protein catabolic process" "0005840=ribosome, 0005875=microtubule associated complex, 0022625=cytosolic large ribosomal subunit" "BcDNA:RE10554, Dub52, Ubi-f, Ub52, DUb52, Ubiquitin fusion 52, CEP52, Ubiq, Rpl40, Ubiquitin, CG2960, ubiquitin, ubiquitin 52-AA extension protein, Ubi-f52" "IPR019954=Ubiquitin conserved site, IPR000626=Ubiquitin domain, IPR001975=Ribosomal protein L40e, IPR019956=Ubiquitin, IPR029071=Ubiquitin-related domain" CG2960 16-Dec-15 2015_12 ENSDARG00000041435(uba52) "YIL148W(RPL40A),YKR094C(RPL40B)" WBGene00006728(ubq-2) ENSXETG00000023202(uba52) "ENSMUSG00000068240(Gm11808),ENSMUSG00000055553(Uba52)" ENSG00000221983(UBA52) " larval stage | third instar , embryonic stage -- adult stage , oogenesis stage && adult stage | female " " embryonic/larval hindgut

, embryonic/larval fat body

, Malpighian tubule

, ovary

, imaginal disc

, embryonic/larval salivary gland

" "lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC00782 IEK -1.286597952 -2.426221723 0.371928196 -4.61537324 1.156605366 1.600366119 FBgn0065785 l(2)SH0436 lethal (2) SH0436 http://flybase.net/reports/FBgn0065785.html gene l(2)SH2 0436 16-Dec-15 2015_12 "lethal,recessive" FBgn0069243 driceless driceless http://flybase.net/reports/FBgn0069243.html gene 0007289=spermatid nucleus differentiation 16-Dec-15 2015_12 spermatid FBgn0004840 Zhr Zygotic hybrid rescue http://flybase.net/reports/FBgn0004840.html gene "Zhr[ts], Zygotic hybrid rescue-temperature sensitive, zygotic hybrid rescue, zhr" 16-Dec-15 2015_12 FBgn0065336 l(2)SH1851 lethal (2) SH1851 http://flybase.net/reports/FBgn0065336.html gene l(2)SH2 1851 16-Dec-15 2015_12 "lethal,recessive" FBgn0058397 CG40397 http://flybase.net/reports/FBgn0058397.html FBan0040397 protein_coding_gene 16-Dec-15 2015_12 FBgn0035842 CG7504 http://flybase.net/reports/FBgn0035842.html protein_coding_gene 0004004=ATP-dependent RNA helicase activity 0005875=microtubule associated complex "IPR008984=SMAD/FHA domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000253=Forkhead-associated (FHA) domain" CG7504 16-Dec-15 2015_12 ENSDARG00000022996 ENSXETG00000006254(SETX) ENSG00000107290(SETX) "viable,female sterile,female fertile" FBgn0027162 l(2)KC-D l(2)Karp and Cherbas D http://flybase.net/reports/FBgn0027162.html gene D 16-Dec-15 2015_12 "lethal,recessive" FBgn0037934 CG6830 http://flybase.net/reports/FBgn0037934.html protein_coding_gene "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG6830 16-Dec-15 2015_12 "viable,fertile" FBgn0043046 cfo centrosome fall off http://flybase.net/reports/FBgn0043046.html gene "0051661=maintenance of centrosome location, 0007096=regulation of exit from mitosis, 0007348=regulation of syncytial blastoderm mitotic cell cycle" 16-Dec-15 2015_12 "lethal,recessive" "mitotic cell cycle | embryonic stage,spindle,centrosome" FBgn0263456 nwk nervous wreck http://flybase.net/reports/FBgn0263456.html "FBgn0035966, FBgn0035967" protein_coding_gene "0005515=protein binding, 0005543=phospholipid binding, 0005070=SH3/SH2 adaptor activity" "0007274=neuromuscular synaptic transmission, 0030510=regulation of BMP signaling pathway, 0008582=regulation of synaptic growth at neuromuscular junction, 0001881=receptor recycling, 0030111=regulation of Wnt signaling pathway, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0030833=regulation of actin filament polymerization" "0005737=cytoplasm, 0031594=neuromuscular junction, 0055037=recycling endosome" "CG4684, CG43479, Nervous Wreck, CG4641, NWK, Nwk, Nervous wreck" "IPR031160=F-BAR domain, IPR001452=SH3 domain, IPR001060=FCH domain" CG43479 16-Dec-15 2015_12 YHR114W(BZZ1) "ENSXETG00000010734(FCHSD2),ENSXETG00000002698(FCHSD1)" "ENSMUSG00000030691(Fchsd2),ENSMUSG00000038524(Fchsd1)" "ENSG00000137478(FCHSD2),ENSG00000197948(FCHSD1)" FBgn0267623 CR45961 http://flybase.net/reports/FBgn0267623.html non_protein_coding_gene CR45961 16-Dec-15 2015_12 FBgn0266801 CG45263 http://flybase.net/reports/FBgn0266801.html "FBgn0263416, FBgn0262729, FBgn0250829, FBgn0243510, FBgn0061464, FBgn0051369, FBgn0051264, FBgn0040530, FBgn0037588, FBgn0037587, FBan0031264, FBgn0028701, FBgn0046787, FBgn0027738, FBgn0086534, FBgn0259181, FBgn0037585, FBan0011718, FBgn0259182, FBgn0051462, FBgn0037586" protein_coding_gene "CG42285, CT32186, CG11729, CG11730, CG11718, mRNA-like ncRNA in embryogenesis 1, MRE1, CG42286, CG11733, CG11731, CG31369/CG31462, BcDNA:GH22170, BcDNA:AT05815, 43462, CG31462, GH22170, anon-EST:Posey178, CG31264, CG43462, GS3056, CG31369" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set" CG45263 16-Dec-15 2015_12 DRSC14363 I -0.740550596 -1.997640744 -0.904398763 0.641417916 -0.020711278 -0.402363167 FBgn0032202 REPTOR-BP REPTOR-binding partner http://flybase.net/reports/FBgn0032202.html FBgn0062903 protein_coding_gene "0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity, 0003682=chromatin binding, 0043565=sequence-specific DNA binding" "0038202=TORC1 signaling, 0042594=response to starvation, 0045893=positive regulation of transcription, DNA-templated, 0044246=regulation of multicellular organismal metabolic process" 0005634=nucleus "DM20, CG18619, BcDNA:RH73910" IPR004827=Basic-leucine zipper domain CG18619 16-Dec-15 2015_12 ENSXETG00000027934(CREBL2) ENSG00000111269(CREBL2) "viable,fertile" FBgn0037161 CG14460 http://flybase.net/reports/FBgn0037161.html protein_coding_gene 16-Dec-15 2015_12 DRSC11720 I 0.937840866 2.351672302 0.933501775 1.062319185 0.793448937 -0.923223044 FBgn0243502 l(2)CB02900 http://flybase.net/reports/FBgn0243502.html gene 16-Dec-15 2015_12 lethal FBgn0002392 l(3)93Di lethal (3) 93Di http://flybase.net/reports/FBgn0002392.html gene "l(3)er12, er12" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0065155 l(3)SH052 lethal (3) SH052 http://flybase.net/reports/FBgn0065155.html gene l(2)SH3 052 16-Dec-15 2015_12 "lethal,recessive" FBgn0022051 l(2)k08222 lethal (2) k08222 http://flybase.net/reports/FBgn0022051.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001772 l(1)M46 lethal (1) M46 http://flybase.net/reports/FBgn0001772.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0060516 l(3)S103707b lethal (3) S103707b http://flybase.net/reports/FBgn0060516.html gene 1037/07 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0034379 CG15073 http://flybase.net/reports/FBgn0034379.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG15073 16-Dec-15 2015_12 viable FBgn0011961 tRNA:R2:84Fc transfer RNA:arg2:84Fc http://flybase.net/reports/FBgn0011961.html "FBgn0003758, FBgn0011947, FBgn0051582, FBgn0060095" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033429=CGU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR31582, AE002708.trna64-ArgACG, tRNA:arg1, tRNA:R1, transfer RNA:arg1, tRNA[arg], chr3R.trna70-ArgACG, tRNA:arg2:84Fc, tRNA[Arg][[2]], tRNA:R:ACG:AE002708-c" CR31582 16-Dec-15 2015_12 FBgn0035568 CG18418 http://flybase.net/reports/FBgn0035568.html FBgn0044685 protein_coding_gene "0022857=transmembrane transporter activity, 0015367=oxoglutarate:malate antiporter activity" "0015742=alpha-ketoglutarate transport, 0015743=malate transport, 0006839=mitochondrial transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" anon-WO0140519.190 "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain, IPR002030=Mitochondrial brown fat uncoupling protein" CG18418 16-Dec-15 2015_12 ENSDARG00000035741(zgc:86898) ENSXETG00000014955(Q566L1_XENTR) viable DRSC08535 K -0.216374123 1.203140915 -0.306216913 0.261852222 1.710548532 -0.231077627 FBgn0050180 CG30180 http://flybase.net/reports/FBgn0050180.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036759 CG5577 http://flybase.net/reports/FBgn0036759.html protein_coding_gene "0016791=phosphatase activity, 0004035=alkaline phosphatase activity, 0004721=phosphoprotein phosphatase activity" 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" 20151379 "IPR023214=HAD-like domain, IPR023215=Nitrophenylphosphatase-like domain, IPR006357=HAD-superfamily hydrolase, subfamily IIA" CG5577 16-Dec-15 2015_12 YDL236W(PHO13) "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0035374 mRpS35 mitochondrial ribosomal protein S35 http://flybase.net/reports/FBgn0035374.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "CG2101, MRP-S28" "IPR019349=Ribosomal protein S24/S35, mitochondrial, conserved domain" CG2101 16-Dec-15 2015_12 ENSDARG00000038456(zgc:114150) WBGene00012697(Y39B6A.39) ENSXETG00000001312(MRPS35) ENSMUSG00000040112(Mrps35) ENSG00000061794(MRPS35) "viable,visible" "trichogen cell,mesothoracic tergum" DRSC08551 E -0.286116412 -0.102567758 -1.74965249 0.187934251 0.188002677 0.814522601 FBgn0020316 anon-92CDa anon-92CDa http://flybase.net/reports/FBgn0020316.html gene 512 16-Dec-15 2015_12 FBgn0058057 CG40057 http://flybase.net/reports/FBgn0058057.html FBan0040057 protein_coding_gene 16-Dec-15 2015_12 FBgn0035317 Oseg2 Outer segment 2 http://flybase.net/reports/FBgn0035317.html protein_coding_gene "0007018=microtubule-based movement, 0035058=nonmotile primary cilium assembly, 0042384=cilium assembly, 0042073=intraciliary transport" "0031513=nonmotile primary cilium, 0030990=intraciliary transport particle, 0005929=cilium, 0005871=kinesin complex" "OSEG, OSM-1, IFT172, selective LIM binding factor, Oseg2, oseg2, CG13809, OSEG2, osm-1" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG13809 16-Dec-15 2015_12 ENSDARG00000041870(ift172) WBGene00003883(osm-1) ENSXETG00000021254(IFT172) ENSMUSG00000038564(Ift172) ENSG00000138002(IFT172) "neurophysiology defective,viable" "trichogen cell,mechanosensory neuron,cilium & cell" FBgn0065818 l(2)SH0376 lethal (2) SH0376 http://flybase.net/reports/FBgn0065818.html gene l(2)SH2 0376 16-Dec-15 2015_12 "lethal,recessive" FBgn0267279 CR45715 http://flybase.net/reports/FBgn0267279.html non_protein_coding_gene CR45715 16-Dec-15 2015_12 FBgn0052119 CG32119 http://flybase.net/reports/FBgn0052119.html "FBgn0045100, FBgn0061465" protein_coding_gene "BcDNA:AT05691, NEST:bs34d09" CG32119 16-Dec-15 2015_12 viable FBgn0259682 Jabba Jabba http://flybase.net/reports/FBgn0259682.html "FBgn0034388, FBgn0062197, FBgn0054020, FBgn0082898" protein_coding_gene "0005811=lipid particle, 0005886=plasma membrane" "BP1008, CG42351, CG15092, 141242_at, CG34020, anon-WO0118547.167, unnamed, CG1509" CG42351 16-Dec-15 2015_12 FBgn0260073 2L3569 http://flybase.net/reports/FBgn0260073.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0065042 2SrRNA 2SrRNA http://flybase.net/reports/FBgn0065042.html rRNA_gene 0022625=cytosolic large ribosomal subunit "2S rRNA, 2S ribosomal RNA, 2SRNA, 2S, 5.8S and 2S ribosomal rRNA" 16-Dec-15 2015_12 FBgn0035743 CG15829 http://flybase.net/reports/FBgn0035743.html protein_coding_gene "0004857=enzyme inhibitor activity, 0050809=diazepam binding, 0000062=fatty-acyl-CoA binding" 0042049=cellular acyl-CoA homeostasis "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR022408=Acyl-CoA-binding protein, ACBP, conserved site, IPR000582=Acyl-CoA-binding protein, ACBP" CG15829 16-Dec-15 2015_12 FBgn0053531 Ddr Discoidin domain receptor http://flybase.net/reports/FBgn0053531.html "FBgn0031796, FBgn0031793, FBgn0031794, FBgn0031795, FBgn0031797" protein_coding_gene "0005524=ATP binding, 0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity" "0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0006468=protein phosphorylation" 0016021=integral component of membrane "CG13985, CG33531, CG11573, CG9488, CG9490, CT33540, DDR" "IPR008979=Galactose-binding domain-like, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR000421=Coagulation factor 5/8 C-terminal domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG33531 16-Dec-15 2015_12 "ENSDARG00000051913(ddr2a),ENSDARG00000058695(ddr2),ENSDARG00000004722" WBGene00016104(ddr-1) "ENSXETG00000023452(),ENSXETG00000004752(DDR2),ENSXETG00000024086(DDR1)" "ENSMUSG00000026674(Ddr2),ENSMUSG00000003534(Ddr1)" "ENSG00000162733(DDR2),ENSG00000137332,ENSG00000204580(DDR1),ENSG00000215522" "viable,visible" "trichogen cell,mesothoracic tergum" DRSC02150 K 0.922384953 -0.493883575 -0.068283599 -0.999411632 0.899173395 1.890413966 FBgn0039125 Ndc1 Ndc1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0039125.html protein_coding_gene 0017056=structural constituent of nuclear pore "0051292=nuclear pore complex assembly, 0022008=neurogenesis" "0012505=endomembrane system, 0005643=nuclear pore" "CG5857, NDC1, Ndc1" IPR019049=Nucleoporin protein Ndc1-Nup CG5857 16-Dec-15 2015_12 ENSDARG00000021120(tmem48) WBGene00007118(npp-22) ENSXETG00000008075(TMEM48) ENSMUSG00000028614(Tmem48) ENSG00000058804(TMEM48) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,supernumerary,trichogen cell,tormogen cell" FBgn0038490 CG5285 http://flybase.net/reports/FBgn0038490.html protein_coding_gene 0017065=single-strand selective uracil DNA N-glycosylase activity IPR005122=Uracil-DNA glycosylase-like CG5285 16-Dec-15 2015_12 ENSDARG00000063611 ENSXETG00000021280(SMUG1) ENSMUSG00000036061(Smug1) ENSG00000123415(SMUG1) "viable,fertile" FBgn0027098 1688-2E 1688-2E http://flybase.net/reports/FBgn0027098.html repeat_region 16-Dec-15 2015_12 FBgn0001820 l(1)sd lethal (1) scheiben enlarged http://flybase.net/reports/FBgn0001820.html gene 16-Dec-15 2015_12 lethal "imaginal disc,embryonic/larval salivary gland" FBgn0037724 Fst Frost http://flybase.net/reports/FBgn0037724.html protein_coding_gene "0009409=response to cold, 0009631=cold acclimation" 0005615=extracellular space "CG9434, frost" CG9434 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,cold stress response defective,female limited" FBgn0031529 CG9662 http://flybase.net/reports/FBgn0031529.html FBgn0047352 protein_coding_gene BcDNA:AT03617 "IPR021149=Oligosaccharyl transferase complex, subunit OST3/OST6" CG9662 16-Dec-15 2015_12 ENSDARG00000035838(ostc) ENSXETG00000021099(TNeu100m23.1) ENSMUSG00000041084(Ostc) "ENSG00000198856(OSTC),ENSG00000213077" "viable,fertile" FBgn0050366 swif swift-tuttle http://flybase.net/reports/FBgn0050366.html FBgn0033284 protein_coding_gene "swift-tuttle, swif, CG2149, CG30366" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30366 16-Dec-15 2015_12 FBgn0034137 CG4945 http://flybase.net/reports/FBgn0034137.html protein_coding_gene "0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0004672=protein kinase activity" "0007498=mesoderm development, 0006468=protein phosphorylation" "CT15864, PKN" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG4945 16-Dec-15 2015_12 "ENSDARG00000021660(bsk146),ENSDARG00000031618(LOC557524),ENSDARG00000056294(LOC559792),ENSDARG00000013548(LOC791840),ENSDARG00000058944(LOC100001826),ENSDARG00000020455(LOC566942),ENSDARG00000057687(zgc:172086)" WBGene00015293(C01C4.3) "ENSXETG00000012254(),ENSXETG00000010325(SBK1),ENSXETG00000016923(),ENSXETG00000019143(SBK2),ENSXETG00000008802(),ENSXETG00000018197()" "ENSMUSG00000042978(Sbk1),ENSMUSG00000030433(Sbk2)" "ENSG00000188322(SBK1),ENSG00000187550(SBK2)" "viable,fertile" FBgn0053481 dpr7 defective proboscis extension response 7 http://flybase.net/reports/FBgn0053481.html protein_coding_gene 0007606=sensory perception of chemical stimulus "CG33481, dpr7, Dpr-7, Dpr7" "IPR003599=Immunoglobulin subtype, IPR013151=Immunoglobulin, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG33481 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) viable FBgn0021919 l(2)k11311 lethal (2) k11311 http://flybase.net/reports/FBgn0021919.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264887 CR44078 http://flybase.net/reports/FBgn0264887.html non_protein_coding_gene CR44078 16-Dec-15 2015_12 FBgn0267945 CR46225 http://flybase.net/reports/FBgn0267945.html non_protein_coding_gene lincRNA.719 CR46225 16-Dec-15 2015_12 FBgn0013317 Pcp19 Pupal-cuticle-protein-19kD http://flybase.net/reports/FBgn0013317.html gene 16-Dec-15 2015_12 FBgn0000671 fliE flightless E http://flybase.net/reports/FBgn0000671.html gene 0007629=flight behavior 16-Dec-15 2015_12 "flightless,heat sensitive" FBgn0030742 CG9919 http://flybase.net/reports/FBgn0030742.html protein_coding_gene CG9919 16-Dec-15 2015_12 FBgn0267288 CR45724 http://flybase.net/reports/FBgn0267288.html non_protein_coding_gene CR45724 16-Dec-15 2015_12 FBgn0267753 CR46084 http://flybase.net/reports/FBgn0267753.html non_protein_coding_gene CR46084 16-Dec-15 2015_12 FBgn0022154 l(2)k05816 lethal (2) k05816 http://flybase.net/reports/FBgn0022154.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260771 Larp7 La related protein 7 http://flybase.net/reports/FBgn0260771.html "FBgn0005639, FBgn0030113" protein_coding_gene "0000166=nucleotide binding, 0097322=7SK snRNA binding" 0006396=RNA processing "0030529=ribonucleoprotein complex, 0005634=nucleus" "CG12058, dLARP7, CG42569" "IPR014886=La protein, RNA-binding domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR002344=Lupus La protein, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006630=RNA-binding protein Lupus La, IPR000504=RNA recognition motif domain" CG42569 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" DRSC18798 I -0.34992358 -1.555242589 0.053018091 -0.851386699 0.032746168 0.04257402 FBgn0011072 l(1)Q25 lethal (1) Q25 http://flybase.net/reports/FBgn0011072.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0028203 l(3)S015601b lethal (3) S015601b http://flybase.net/reports/FBgn0028203.html gene "0156/01, l(3)S015601" 16-Dec-15 2015_12 "lethal,recessive" FBgn0034428 CG18606 http://flybase.net/reports/FBgn0034428.html protein_coding_gene IPR016181=Acyl-CoA N-acyltransferase CG18606 16-Dec-15 2015_12 viable FBgn0036335 mRpL20 mitochondrial ribosomal protein L20 http://flybase.net/reports/FBgn0036335.html FBgn0062134 protein_coding_gene "0019843=rRNA binding, 0003735=structural constituent of ribosome" 0006412=translation 0005762=mitochondrial large ribosomal subunit "anon-WO0118547.265, CG11258, L20" IPR005813=Ribosomal protein L20 CG11258 16-Dec-15 2015_12 WBGene00012992(Y48C3A.10) ENSXETG00000011118(MRPL20) ENSMUSG00000029066(Mrpl20) "ENSG00000215734,ENSG00000131586" "viable,fertile,visible" trichogen cell FBgn0060467 l(3)S113204a lethal (3) S113204a http://flybase.net/reports/FBgn0060467.html gene 1132/04 16-Dec-15 2015_12 "lethal,lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0037975 CG3397 http://flybase.net/reports/FBgn0037975.html protein_coding_gene 0016491=oxidoreductase activity "0006813=potassium ion transport, 0055114=oxidation-reduction process" 0008076=voltage-gated potassium channel complex "IPR023210=NADP-dependent oxidoreductase domain, IPR020471=Aldo/keto reductase subgroup, IPR001395=Aldo/keto reductase" CG3397 16-Dec-15 2015_12 YMR041C(ARA2) WBGene00003176(mec-14) ENSXETG00000016911() FBgn0020330 anon-6C5 anon-6C5 http://flybase.net/reports/FBgn0020330.html gene "unnamed, 6C5" 16-Dec-15 2015_12 FBgn0035232 CG12099 http://flybase.net/reports/FBgn0035232.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0051865=protein autoubiquitination "IPR001841=Zinc finger, RING-type, IPR018957=Zinc finger, C3HC4 RING-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG12099 16-Dec-15 2015_12 YLR427W(MAG2) ENSXETG00000012226(rnf10) ENSMUSG00000041740(Rnf10) ENSG00000022840(RNF10) "viable,fertile" FBgn0016892 l(3)64Cb lethal (3) 64Cb http://flybase.net/reports/FBgn0016892.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060471 l(3)S112202b lethal (3) S112202b http://flybase.net/reports/FBgn0060471.html gene 1122/02 16-Dec-15 2015_12 lethal FBgn0085483 CG34454 http://flybase.net/reports/FBgn0085483.html "FBgn0082880, FBgn0054018" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0030162=regulation of proteolysis CG34018 IPR002350=Kazal domain CG34454 16-Dec-15 2015_12 FBgn0260102 2L0196 http://flybase.net/reports/FBgn0260102.html gene 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,somatic clone" FBgn0070043 3R-259-18 3R-259-18 http://flybase.net/reports/FBgn0070043.html gene 0007310=oocyte dorsal/ventral axis specification 16-Dec-15 2015_12 "dorsal appendage,germline clone,non-rescuable maternal effect,egg,maternal effect" FBgn0020816 l(3)Fox lethal (3) Fox http://flybase.net/reports/FBgn0020816.html gene 16-Dec-15 2015_12 FBgn0043891 l(3)113 lethal (3) 113 http://flybase.net/reports/FBgn0043891.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058173 CG40173 http://flybase.net/reports/FBgn0058173.html protein_coding_gene 16-Dec-15 2015_12 FBgn0016004 l(3)63Ec lethal (3) 63Ec http://flybase.net/reports/FBgn0016004.html gene "l63Ec, l(3)SH2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0013241 E(var)222 E(var)222 http://flybase.net/reports/FBgn0013241.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0060967 l(3)S030704b lethal (3) S030704b http://flybase.net/reports/FBgn0060967.html gene 0307/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0034840 CG3124 http://flybase.net/reports/FBgn0034840.html FBgn0044640 protein_coding_gene anon-WO0140519.230 CG3124 16-Dec-15 2015_12 FBgn0060884 l(3)S044805 lethal (3) S044805 http://flybase.net/reports/FBgn0060884.html gene 0448/05 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053723 CG33723 http://flybase.net/reports/FBgn0053723.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33723 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0035449 CG14971 http://flybase.net/reports/FBgn0035449.html protein_coding_gene 0000138=Golgi trans cisterna IPR004853=Sugar phosphate transporter domain CG14971 16-Dec-15 2015_12 YML038C(YMD8) WBGene00021637(Y47G6A.7) ENSXETG00000007362(slc35c2) ENSMUSG00000017664(Slc35c2) ENSG00000080189(SLC35C2) "viable,fertile" FBgn0028169 l(3)S027607 lethal (3) S027607 http://flybase.net/reports/FBgn0028169.html gene 0276/07 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0036143 CG14142 http://flybase.net/reports/FBgn0036143.html protein_coding_gene IPR025257=Domain of unknown function DUF4205 CG14142 16-Dec-15 2015_12 ENSDARG00000069867(LOC569648) ENSMUSG00000078720(Fam188b2) ENSG00000214237 viable DRSC10145 E -0.325105954 -0.253453478 -1.680122873 -0.265959501 -0.324411199 -0.671800505 FBgn0024724 Su(var)38D Su(var)38D http://flybase.net/reports/FBgn0024724.html gene unnamed 16-Dec-15 2015_12 FBgn0001459 l(1)7Dm lethal (1) 7Dm http://flybase.net/reports/FBgn0001459.html gene RA5 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,germline clone,maternal effect" FBgn0035477 CG14982 http://flybase.net/reports/FBgn0035477.html protein_coding_gene "IPR025741=Centrosome-associated, FAM110, C-terminal domain" CG14982 16-Dec-15 2015_12 viable FBgn0005075 fs(2)OW216 female sterile (2) OW216 http://flybase.net/reports/FBgn0005075.html gene 16-Dec-15 2015_12 FBgn0003427 slm slim http://flybase.net/reports/FBgn0003427.html gene 16-Dec-15 2015_12 "developmental rate defective,small body,partially lethal - majority die,viable,fertile,visible,recessive" "abdomen,wing,adult abdomen" FBgn0033730 Cpr49Ag Cuticular protein 49Ag http://flybase.net/reports/FBgn0033730.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG8511, DmelCpr49Ag" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8511 16-Dec-15 2015_12 viable FBgn0263444 CR43467 http://flybase.net/reports/FBgn0263444.html non_protein_coding_gene CR43467 16-Dec-15 2015_12 FBgn0041785 S(Sev-CycE)D17 S(Sev-CycE)D17 http://flybase.net/reports/FBgn0041785.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031087 CG12656 http://flybase.net/reports/FBgn0031087.html "FBgn0047107, FBgn0062935" protein_coding_gene "BcDNA:RH47776, BcDNA:RE41492" 16-Dec-15 2015_12 FBgn0263916 Ent2 Equilibrative nucleoside transporter 2 http://flybase.net/reports/FBgn0263916.html "FBgn0263858, FBgn0026585, FBgn0031833, FBgn0051911" protein_coding_gene 0005337=nucleoside transmembrane transporter activity "0008306=associative learning, 0007268=synaptic transmission, 0015858=nucleoside transport, 0090281=negative regulation of calcium ion import" "0005886=plasma membrane, 0016021=integral component of membrane" "LD04971, BEST:LD04971, DmEnt2, CG11045, CG31911, equilibrative nucleoside transporter, equilibrative nucleoside transporter 2, DmENT2, ent2, P124, Equilibrative Nucleoside Transporter 2" "IPR020846=Major facilitator superfamily domain, IPR002259=Equilibrative nucleoside transporter" CG31911 16-Dec-15 2015_12 "WBGene00001320(ent-1),WBGene00010701(ent-2),WBGene00010510(ent-3)" FBgn0058159 CG40159 http://flybase.net/reports/FBgn0058159.html FBan0040159 protein_coding_gene 16-Dec-15 2015_12 FBgn0050369 CG30369 http://flybase.net/reports/FBgn0050369.html FBgn0045386 protein_coding_gene NEST:bs06h11 CG30369 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0037652 CG11980 http://flybase.net/reports/FBgn0037652.html FBgn0062091 protein_coding_gene anon-WO0118547.327 IPR003226=Metal-dependent protein hydrolase CG11980 16-Dec-15 2015_12 ENSDARG00000069977 YER156C() WBGene00007787(C27H6.8) ENSXETG00000012666(C12orf10) ENSMUSG00000001285(Myg1) ENSG00000139637(C12orf10) viable FBgn0053998 CG33998 http://flybase.net/reports/FBgn0053998.html FBgn0082848 protein_coding_gene "unnamed, BP1058" CG33998 16-Dec-15 2015_12 FBgn0061032 l(3)S024106 lethal (3) S024106 http://flybase.net/reports/FBgn0061032.html gene 0241/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0019871 l(3)96Ac lethal (3) 96Ac http://flybase.net/reports/FBgn0019871.html gene "anon-96Ac, 291.6" 16-Dec-15 2015_12 "lethal,recessive" FBgn0028970 ë_ggt-II ë_ subunit of type II geranylgeranyl transferase http://flybase.net/reports/FBgn0028970.html FBgn0031480 protein_coding_gene "0004663=Rab geranylgeranyltransferase activity, 0004662=CAAX-protein geranylgeranyltransferase activity" 0018344=protein geranylgeranylation 0005968=Rab-protein geranylgeranyltransferase complex "betaggt, RabGGTbeta, CG18627, betaggt II, GGT-II beta, betaggt-II" "IPR026873=Geranylgeranyl transferase type-2 subunit beta, IPR001330=PFTB repeat, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG18627 16-Dec-15 2015_12 ENSDARG00000068587(rabggtb) YPR176C(BET2) WBGene00015099(ggtb-1) ENSXETG00000002979(RABGGTB) ENSMUSG00000038975(Rabggtb) ENSG00000137955(RABGGTB) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0024885 l(2)02438 lethal (2) 02438 http://flybase.net/reports/FBgn0024885.html gene 2438 16-Dec-15 2015_12 "lethal,recessive" FBgn0002328 l(3)86Fg lethal (3) 86Fg http://flybase.net/reports/FBgn0002328.html gene "l(3)ck7, 0549/07, 549/7, ck7" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0046222 CG1109 http://flybase.net/reports/FBgn0046222.html FBgn0037361 protein_coding_gene 0048812=neuron projection morphogenesis "WDR33, BcDNA:LD24014" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat" CG1109 16-Dec-15 2015_12 ENSDARG00000018272 WBGene00011051(pfs-2) ENSMUSG00000024400(Wdr33) ENSG00000136709(WDR33) lethal DRSC12162 I 2.078679876 2.600321646 0.590784156 -1.081009484 -0.890575441 0.183609383 FBgn0004396 CrebA Cyclic-AMP response element binding protein A http://flybase.net/reports/FBgn0004396.html "FBgn0004848, FBgn0010804, FBgn0041115, FBgn0062892" protein_coding_gene "0001158=enhancer sequence-specific DNA binding, 0042803=protein homodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0007431=salivary gland development, 0035293=chitin-based larval cuticle pattern formation, 0009953=dorsal/ventral pattern formation, 0045893=positive regulation of transcription, DNA-templated, 0008363=larval chitin-based cuticle development, 0006366=transcription from RNA polymerase II promoter, 0007435=salivary gland morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005700=polytene chromosome" "Box B-binding factor 2, BBF2_DROME, crebA, DM4, dCreb-A, dCrebA, CRE-BP, l(3)03576, cAMP response element binding protein, CREBA, dCREBA, BcDNA:SD05937, dCREB-A, cAMP response element binding protein A, CREB, CREB-A, CG7450, Creb, cyclic AMP response element binding protein, BBF-2, BOX B Binding Factor-2, CREB-a, Creb-A, Creb A, creb, Bbbf2" "IPR001630=cAMP response element binding (CREB) protein, IPR004827=Basic-leucine zipper domain" CG7450 16-Dec-15 2015_12 "ENSDARG00000015793(id:ibd2573),ENSDARG00000063563" WBGene00016162(C27D6.4) "ENSMUSG00000027230(Creb3l1),ENSMUSG00000038648(Creb3l2)" "ENSG00000182158(CREB3L2),ENSG00000157613(CREB3L1)" " adult stage | male , adult stage , larval stage | third instar , embryonic stage , adult stage && oogenesis stage , embryonic stage -- adult stage " " ejaculatory duct

, adult midgut

, ejaculatory bulb

, embryonic/larval digestive system

, seminal vesicle

, embryonic/larval salivary gland

, embryonic/larval fat body

, embryonic/larval trachea

, follicle cell

, adult brain

, optic lobe

, adult salivary gland

,

, adult proventriculus

" " embryonic stage | stage 11-12 , oogenesis stage && adult stage | female " " embryonic salivary gland

, ovary

" "visible,somatic clone,viable,fertile,lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "larva,embryonic/larval cuticle,denticle belt,ommatidium,somatic clone,eye photoreceptor cell,embryonic/larval salivary gland,eye,ectopic" FBgn0016928 smi27E smell impaired 27E http://flybase.net/reports/FBgn0016928.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0030321 CG1703 http://flybase.net/reports/FBgn0030321.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0043190=ATP-binding cassette (ABC) transporter complex "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG1703 16-Dec-15 2015_12 ENSDARG00000031795(abcf1) WBGene00006512(abcf-1) ENSXETG00000024088(ABCF1) ENSMUSG00000038762(Abcf1) "ENSG00000206410,ENSG00000206490,ENSG00000204574(ABCF1)" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031763 CG13996 http://flybase.net/reports/FBgn0031763.html protein_coding_gene "IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain" CG13996 16-Dec-15 2015_12 viable FBgn0082672 Fill Firewall http://flybase.net/reports/FBgn0082672.html gene 0019991=septate junction assembly 16-Dec-15 2015_12 FBgn0060557 l(3)S097405 lethal (3) S097405 http://flybase.net/reports/FBgn0060557.html gene 0974/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0026390 Or33c Odorant receptor 33c http://flybase.net/reports/FBgn0026390.html protein_coding_gene "0004888=transmembrane signaling receptor activity, 0004984=olfactory receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR33B.3, DOR71, Or71, 33B.3, CG5006, dor71, Olfactory receptor 33B.3, Or33B.3, 33c, AN2" "IPR004117=Olfactory receptor, Drosophila" CG5006 16-Dec-15 2015_12 " adult stage ," sensory neuron &&of maxillary palpus

viable DRSC03388 I -1.530345874 0.792747505 -0.20167203 0.024674066 -0.858406151 -0.192978813 FBgn0037460 sowi solwind http://flybase.net/reports/FBgn0037460.html protein_coding_gene 0005509=calcium ion binding "sowi, solwind, CG15178" "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR028846=Recoverin family, IPR002048=EF-hand domain" CG15178 16-Dec-15 2015_12 viable DRSC12558 I 2.295027094 -0.184820699 -0.06168727 -0.059210542 -0.731451177 0.151891585 FBgn0028871 Cpr35B Cuticular protein 35B http://flybase.net/reports/FBgn0028871.html protein_coding_gene "0008011=structural constituent of pupal chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DS06283.4, DmelCpr35B, CG3474, BG:DS06238.4" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG3474 16-Dec-15 2015_12 viable FBgn0024661 l(2)k07020 lethal (2) k07020 http://flybase.net/reports/FBgn0024661.html gene 70/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0263083 CG43351 http://flybase.net/reports/FBgn0263083.html protein_coding_gene CG42725 CG43351 16-Dec-15 2015_12 FBgn0261681 CG42728 http://flybase.net/reports/FBgn0261681.html "FBgn0053984, FBgn0036506, FBgn0036507" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "CG17014, CG33984, CG7973" IPR002557=Chitin binding domain CG42728 16-Dec-15 2015_12 FBgn0038881 CG16791 http://flybase.net/reports/FBgn0038881.html FBgn0046355 protein_coding_gene 0006909=phagocytosis anon-WO0172774.78 CG16791 16-Dec-15 2015_12 WBGene00007746(C26D10.6) "viable,fertile" DRSC13471 IE -0.122468117 1.672170139 -4.424384737 0.02084262 0.418129969 1.2766258 FBgn0065337 l(2)SH1846 lethal (2) SH1846 http://flybase.net/reports/FBgn0065337.html gene l(2)SH2 1846 16-Dec-15 2015_12 "lethal,recessive" FBgn0044352 Quasimodo\pol pol http://flybase.net/reports/FBgn0044352.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration cruiser\pol "IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR000477=Reverse transcriptase domain, IPR021109=Aspartic peptidase domain" 16-Dec-15 2015_12 FBgn0261730 EC1650 http://flybase.net/reports/FBgn0261730.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0004071 fs(2)mel5 female sterile (2) maternal effect lethal 5 http://flybase.net/reports/FBgn0004071.html gene mel 5 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0031258 CG4297 http://flybase.net/reports/FBgn0031258.html protein_coding_gene CG4297 16-Dec-15 2015_12 viable FBgn0031196 CG17599 http://flybase.net/reports/FBgn0031196.html protein_coding_gene 0042384=cilium assembly "0030992=intraciliary transport particle B, 0005929=cilium" CLUAP1 IPR019366=Clusterin-associated protein-1 CG17599 16-Dec-15 2015_12 ENSDARG00000038564 WBGene00001119(dyf-3) ENSXETG00000010321(CLUAP1) ENSMUSG00000014232(Cluap1) ENSG00000103351(CLUAP1) viable FBgn0029705 CG12693 http://flybase.net/reports/FBgn0029705.html protein_coding_gene CG12693 16-Dec-15 2015_12 viable FBgn0000312 cht chaetae http://flybase.net/reports/FBgn0000312.html gene chaeta 16-Dec-15 2015_12 scutellar bristle FBgn0053805 His-ë¬:CR33805 His-ë¬:CR33805 http://flybase.net/reports/FBgn0053805.html pseudogene_attribute CR33805 CR33805 16-Dec-15 2015_12 FBgn0058100 CR40100 http://flybase.net/reports/FBgn0058100.html FBan0040100 pseudogene_attribute CG40100 CR40100 16-Dec-15 2015_12 FBgn0019796 l(1)10 lethal (1) 10 http://flybase.net/reports/FBgn0019796.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030195 CG2898 http://flybase.net/reports/FBgn0030195.html protein_coding_gene CG2898 16-Dec-15 2015_12 "partially lethal - majority die,visible" tormogen cell FBgn0002054 l(2)37Fg lethal (2) 37Fg http://flybase.net/reports/FBgn0002054.html gene l(2)O9 16-Dec-15 2015_12 lethal FBgn0020554 cro croaker http://flybase.net/reports/FBgn0020554.html gene "0045433=male courtship behavior, veined wing generated song production" 16-Dec-15 2015_12 "courtship behavior defective,male,female,flight defective,wild-type" FBgn0040104 lectin-24A lectin-24A http://flybase.net/reports/FBgn0040104.html FBgn0031567 protein_coding_gene "0005534=galactose binding, 0030246=carbohydrate binding" "lectin-24a, AC 005149A, CG3410, AC005149a, Lectin24A" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG3410 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000040963(Asgr2),ENSMUSG00000020884(Asgr1),ENSMUSG00000000318(Clec10a),ENSMUSG00000040950(Mgl2),ENSMUSG00000036103(Colec12),ENSMUSG00000034783(Cd207)" "ENSG00000118004(COLEC11),ENSG00000220191,ENSG00000165471(MBL2),ENSG00000184374(COLEC10),ENSG00000133661(SFTPD),ENSG00000182314,ENSG00000122854,ENSG00000122852(SFTPA1),ENSG00000185303(SFTPA2)" viable FBgn0030874 Spt7 Spt7 http://flybase.net/reports/FBgn0030874.html protein_coding_gene 0004402=histone acetyltransferase activity 0043966=histone H3 acetylation "0005634=nucleus, 0000124=SAGA complex" "dSpt7, cg6506, CG6506, Spt7" CG6506 16-Dec-15 2015_12 ENSG00000119760(SUPT7L) viable FBgn0266321 CR44986 http://flybase.net/reports/FBgn0266321.html non_protein_coding_gene CR44986 16-Dec-15 2015_12 FBgn0003602 Su(var)3-11 Suppressor of variegation 3-11 http://flybase.net/reports/FBgn0003602.html gene "Su-var(3)111, Su-var(3)11, Su(var)3-111" 16-Dec-15 2015_12 FBgn0065509 l(2)SH1180 lethal (2) SH1180 http://flybase.net/reports/FBgn0065509.html gene l(2)SH2 1180 16-Dec-15 2015_12 "lethal,recessive" FBgn0265716 CR44523 http://flybase.net/reports/FBgn0265716.html non_protein_coding_gene "lincRNA.457, incRNA.457" CR44523 16-Dec-15 2015_12 FBgn0024260 acd(2)5N15 auditory courtship defective 5N15 http://flybase.net/reports/FBgn0024260.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0011188 l(1)296-13 lethal (1) 296-13 http://flybase.net/reports/FBgn0011188.html FBgn0010201 gene 296-13 16-Dec-15 2015_12 "lethal,recessive" FBgn0000192 Bkm BKM sequence element http://flybase.net/reports/FBgn0000192.html satellite_DNA BKM 16-Dec-15 2015_12 FBgn0014048 Su(tor)2-237 Su(tor)2-237 http://flybase.net/reports/FBgn0014048.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0034925 CG5339 http://flybase.net/reports/FBgn0034925.html protein_coding_gene drev "IPR007884=DREV methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG5339 16-Dec-15 2015_12 ENSDARG00000060001(zgc:153060) WBGene00020199(T03G11.6) ENSXETG00000016660(drev1) ENSMUSG00000030876(Mettl9) ENSG00000197006(METTL9) viable FBgn0085527 CG40858 http://flybase.net/reports/FBgn0085527.html FBan0040858 protein_coding_gene 16-Dec-15 2015_12 FBgn0029811 Cpr5C Cuticular protein 5C http://flybase.net/reports/FBgn0029811.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG4052 "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG4052 16-Dec-15 2015_12 viable FBgn0086245 grk::yl http://flybase.net/reports/FBgn0086245.html engineered_fusion_gene Grk-Yl 16-Dec-15 2015_12 FBgn0005377 x8 x8 http://flybase.net/reports/FBgn0005377.html gene 16-Dec-15 2015_12 FBgn0032085 CG9555 http://flybase.net/reports/FBgn0032085.html protein_coding_gene CG9555 16-Dec-15 2015_12 "viable,fertile" FBgn0084815 CG11091 http://flybase.net/reports/FBgn0084815.html FBgn0039931 protein_coding_gene 16-Dec-15 2015_12 DRSC17199 IE -1.630446028 -0.978279208 -1.975595126 -0.4317093 0.85163185 0.272000638 FBgn0060833 l(3)S050110b lethal (3) S050110b http://flybase.net/reports/FBgn0060833.html gene 0501/10 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0037514 CG10919 http://flybase.net/reports/FBgn0037514.html protein_coding_gene CG10919 16-Dec-15 2015_12 "viable,fertile" FBgn0011247 ms(3)90E male sterile (3) 90E http://flybase.net/reports/FBgn0011247.html gene 0007286=spermatid development 16-Dec-15 2015_12 "male sterile,partially lethal - majority die" FBgn0001042 fs(3)HO5B female sterile (3) HO5B http://flybase.net/reports/FBgn0001042.html gene "fs(3)f2, fs(3)f2[5A]" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0033554 Lsm10 Lsm10 http://flybase.net/reports/FBgn0033554.html protein_coding_gene "0006397=mRNA processing, 0006398=histone mRNA 3'-end processing" "0035363=histone locus body, 0016604=nuclear body, 0071254=cytoplasmic U snRNP body" "dLsm10, CG12938" "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type" CG12938 16-Dec-15 2015_12 ENSDARG00000063530 ENSXETG00000027631(lsm10) ENSG00000181817(LSM10) "viable,fertile,male fertile,female fertile,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040860 CG11264 http://flybase.net/reports/FBgn0040860.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000189 bk buckled http://flybase.net/reports/FBgn0000189.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,male fertile" "wing,wing vein,eye,scutellar bristle,leg,sex comb,macrochaeta" FBgn0261570 CG42684 http://flybase.net/reports/FBgn0261570.html "FBgn0030866, FBgn0259165, FBgn0052559, FBgn0052560, FBgn0030865, FBgn0030867" protein_coding_gene 0005096=GTPase activator activity "0046580=negative regulation of Ras protein signal transduction, 0007265=Ras protein signal transduction, 0043087=regulation of GTPase activity, 0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior" 0045179=apical cortex "CG42270, CG15816, CG5960, CG32559, CG5898, CG32560" "IPR001936=Ras GTPase-activating protein, IPR001849=Pleckstrin homology domain, IPR023152=Ras GTPase-activating protein, conserved site, IPR000008=C2 domain, IPR021887=Domain of unknown function DUF3498, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR008936=Rho GTPase activation protein" CG42684 16-Dec-15 2015_12 "ENSDARG00000069484(LOC100002454),ENSDARG00000063713(LOC562404),ENSDARG00000069765" WBGene00001516(gap-2) ENSXETG00000000667() "ENSMUSG00000026883(Dab2ip),ENSMUSG00000070565(Rasal2),ENSMUSG00000067629" "ENSG00000136848(DAB2IP),ENSG00000075391(RASAL2),ENSG00000197283(SYNGAP1)" FBgn0259473 C502 http://flybase.net/reports/FBgn0259473.html gene 16-Dec-15 2015_12 visible wing vein FBgn0019868 anon-B2 anon-B2 http://flybase.net/reports/FBgn0019868.html gene B2 16-Dec-15 2015_12 FBgn0002660 mat(2)cell-I maternal effect cellularisation defect I http://flybase.net/reports/FBgn0002660.html gene 0007349=cellularization mat(2)cellQQ55 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" "stage 5 embryo,embryonic/first instar larval cuticle" FBgn0044346 scratch-like1 scratch-like1 http://flybase.net/reports/FBgn0044346.html gene 16-Dec-15 2015_12 FBgn0051081 TwdlR TweedleR http://flybase.net/reports/FBgn0051081.html FBgn0039442 protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix "CG14240, CG14241, CG31081" IPR004145=Domain of unknown function DUF243 CG31081 16-Dec-15 2015_12 viable FBgn0259354 C367 http://flybase.net/reports/FBgn0259354.html gene 16-Dec-15 2015_12 "visible,lethal" "wing hair,chaeta" FBgn0062928 pncr009:3L putative noncoding RNA 009:3L http://flybase.net/reports/FBgn0062928.html FBgn0053940 pseudogene_attribute "pncr009, BcDNA:RH57193, CR33940, hp-pncr009" CR33940 16-Dec-15 2015_12 FBgn0011999 tRNA:V3b:84Db transfer RNA:val3b:84Db http://flybase.net/reports/FBgn0011999.html "FBgn0003853, FBgn0011997, FBgn0051512, FBgn0060024" tRNA_gene "0033452=GUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "Val-3b, AE002699.trna12-ValCAC, tRNA:val3b:84Db, valine tRNA, chr3R.trna5-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002699-c, CR31512, tRNA[Val][[3b]]" CR31512 16-Dec-15 2015_12 FBgn0034086 CG8441 http://flybase.net/reports/FBgn0034086.html protein_coding_gene IPR009548=Protein of unknown function DUF1168 CG8441 16-Dec-15 2015_12 ENSDARG00000033126(zgc:110608) WBGene00018132(F37A4.2) ENSXETG00000024610(prkrip1) ENSMUSG00000039737(Prkrip1) ENSG00000128563(PRKRIP1) "viable,visible" trichogen cell FBgn0043038 l(2)42Bf lethal (2) 42Bf http://flybase.net/reports/FBgn0043038.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051739 CG31739 http://flybase.net/reports/FBgn0051739.html FBgn0032611 protein_coding_gene "0003676=nucleic acid binding, 0004812=aminoacyl-tRNA ligase activity, 0005524=ATP binding" 0006418=tRNA aminoacylation for protein translation 0005737=cytoplasm CG17938 "IPR004115=GAD-like domain, IPR004365=OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004364=Aminoacyl-tRNA synthetase, class II (D/K/N), IPR006195=Aminoacyl-tRNA synthetase, class II, IPR002312=Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR018150=Aminoacyl-tRNA synthetase, class II (D/K/N)-like, IPR012340=Nucleic acid-binding, OB-fold, IPR004524=Aspartate-tRNA ligase, bacterial/mitochondrial-type" CG31739 16-Dec-15 2015_12 ENSDARG00000060861(dars2) YPL104W(MSD1) WBGene00001095(dars-2) ENSXETG00000020014(DARS2) ENSMUSG00000026709(Dars2) ENSG00000117593(DARS2) "viable,fertile,visible" trichogen cell FBgn0263130 CR43372 http://flybase.net/reports/FBgn0263130.html non_protein_coding_gene CR43372 16-Dec-15 2015_12 FBgn0004142 GATA-sequence GATA element http://flybase.net/reports/FBgn0004142.html repeat_region "GATA5, GATA4, GATA12, GATA6, GATA9, GATA" 16-Dec-15 2015_12 FBgn0266218 CR44913 http://flybase.net/reports/FBgn0266218.html non_protein_coding_gene CR44913 16-Dec-15 2015_12 FBgn0024546 l(3)L3560 lethal (3) L3560 http://flybase.net/reports/FBgn0024546.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004684 ju jumper http://flybase.net/reports/FBgn0004684.html gene 16-Dec-15 2015_12 flightless wing FBgn0263650 CR43641 http://flybase.net/reports/FBgn0263650.html non_protein_coding_gene CR43641 16-Dec-15 2015_12 FBgn0022093 l(2)k07245 lethal (2) k07245 http://flybase.net/reports/FBgn0022093.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0000974 fs(2)HO20 female sterile (2) HO20 http://flybase.net/reports/FBgn0000974.html gene fs(2)20B 16-Dec-15 2015_12 "female sterile,recessive" ovary FBgn0026344 Su(rdgB)83 Su(rdgB)83 http://flybase.net/reports/FBgn0026344.html gene 16-Dec-15 2015_12 FBgn0010144 l(3)62Bh lethal (3) 62Bh http://flybase.net/reports/FBgn0010144.html gene "l(3)Bh, dre5, l(3)dre5" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0265098 CR44203 http://flybase.net/reports/FBgn0265098.html non_protein_coding_gene CR44203 16-Dec-15 2015_12 FBgn0013547 l(2)Su(Sp) lethal (2) Su(Sp) http://flybase.net/reports/FBgn0013547.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259254 EP-620 http://flybase.net/reports/FBgn0259254.html gene 16-Dec-15 2015_12 "visible,lethal" "wing hair,wing,wing vein" FBgn0264519 btl::ft http://flybase.net/reports/FBgn0264519.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0050006 CG30006 http://flybase.net/reports/FBgn0050006.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000161 bat bat http://flybase.net/reports/FBgn0000161.html gene "extended-b, ext-b" 16-Dec-15 2015_12 "visible,recessive" wing FBgn0001426 l(1)6Eb lethal (1) 6Eb http://flybase.net/reports/FBgn0001426.html gene "jnLX, l(1)jnLX, JNLX" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage" wing FBgn0034005 ItgaPS4 Integrin alphaPS4 subunit http://flybase.net/reports/FBgn0034005.html protein_coding_gene "0004872=receptor activity, 0046982=protein heterodimerization activity, 0050839=cell adhesion molecule binding" "0033627=cell adhesion mediated by integrin, 0007155=cell adhesion, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0001555=oocyte growth, 0007160=cell-matrix adhesion" "0016021=integral component of membrane, 0008305=integrin complex" "alphaPS4, integrin alphaPS4 subunit, alpha-PS4, CT37393, ItgalphaPS4, alphaPS4 integrin, alpha-ps4, Integrin alphaPS4 subunit, CG16827" "IPR013519=Integrin alpha beta-propellor, IPR000413=Integrin alpha chain, IPR013649=Integrin alpha-2, IPR018184=Integrin alpha chain, C-terminal cytoplasmic region, conserved site" CG16827 16-Dec-15 2015_12 viable FBgn0058254 CR40254 http://flybase.net/reports/FBgn0058254.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0259228 C3G C3G ortholog (H. sapiens) http://flybase.net/reports/FBgn0259228.html "FBgn0026145, FBgn0029902" protein_coding_gene "0017034=Rap guanyl-nucleotide exchange factor activity, 0005088=Ras guanyl-nucleotide exchange factor activity" "0043087=regulation of GTPase activity, 0045214=sarcomere organization, 0043547=positive regulation of GTPase activity, 0007525=somatic muscle development, 0007265=Ras protein signal transduction, 0016203=muscle attachment" "C(3)G, DC3G, CG42328, CG3126, c(3)G, DC3-G, C3G, CG14436" "IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR023578=Ras guanine nucleotide exchange factor domain, IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR019804=Ras guanine-nucleotide exchange factor, conserved site" CG42328 16-Dec-15 2015_12 YLR310C(CDC25) WBGene00021320(Y34B4A.4) ENSXETG00000001485(rapgef1) ENSMUSG00000039844(Rapgef1) ENSG00000107263(RAPGEF1) " embryonic stage | stage >=4 , embryonic stage | stage 14 , embryonic stage | stage 14 | late , embryonic stage | stage 11 " " embryonic/larval foregut

, segment | segmentally repeated pattern

, visceral mesoderm

, embryonic/larval hindgut

" FBgn0065727 l(2)SH0559 lethal (2) SH0559 http://flybase.net/reports/FBgn0065727.html gene l(2)SH2 0559 16-Dec-15 2015_12 "lethal,recessive" FBgn0265454 CR44354 http://flybase.net/reports/FBgn0265454.html non_protein_coding_gene CR44354 16-Dec-15 2015_12 FBgn0267040 CR45484 http://flybase.net/reports/FBgn0267040.html non_protein_coding_gene lincRNA.947 CR45484 16-Dec-15 2015_12 FBgn0040187 l(1)G0214 lethal (1) G0214 http://flybase.net/reports/FBgn0040187.html gene 16-Dec-15 2015_12 "partially lethal - majority die,male,female,recessive" FBgn0062592 Mod(var)1552 Mod(var)1552 http://flybase.net/reports/FBgn0062592.html gene 0006342=chromatin silencing 1552 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0002106 l(2)57Ec lethal (2) 57Ec http://flybase.net/reports/FBgn0002106.html gene "l(2)57DEFc, l(2)ES15" 16-Dec-15 2015_12 lethal FBgn0052570 TwdlY TweedleY http://flybase.net/reports/FBgn0052570.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix "CG32570, Tweedle Y" IPR004145=Domain of unknown function DUF243 CG32570 16-Dec-15 2015_12 FBgn0264310 CR43785 http://flybase.net/reports/FBgn0264310.html non_protein_coding_gene lincRNA.405 CR43785 16-Dec-15 2015_12 FBgn0260058 2L4081 http://flybase.net/reports/FBgn0260058.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0085692 CG41561 http://flybase.net/reports/FBgn0085692.html FBan0041561 protein_coding_gene CG41561 16-Dec-15 2015_12 FBgn0265255 CR44269 http://flybase.net/reports/FBgn0265255.html non_protein_coding_gene lincRNA.218 CR44269 16-Dec-15 2015_12 FBgn0034442 CG11257 http://flybase.net/reports/FBgn0034442.html protein_coding_gene "0020037=heme binding, 0016491=oxidoreductase activity" 0055114=oxidation-reduction process "IPR001433=Oxidoreductase FAD/NAD(P)-binding, IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR008333=Oxidoreductase, FAD-binding domain, IPR001834=NADH:cytochrome b5 reductase (CBR), IPR017938=Riboflavin synthase-like beta-barrel, IPR001199=Cytochrome b5-like heme/steroid binding domain, IPR018506=Cytochrome b5, heme-binding site, IPR008978=HSP20-like chaperone" CG11257 16-Dec-15 2015_12 ENSDARG00000020898(cyb5r4) WBGene00013123(Y52B11A.3) ENSXETG00000022592(TGas070l21.1) ENSMUSG00000032872(Cyb5r4) ENSG00000065615(CYB5R4) "viable,fertile" FBgn0267451 CR45801 http://flybase.net/reports/FBgn0267451.html non_protein_coding_gene AT12039 CR45801 16-Dec-15 2015_12 FBgn0011566 Bzd Buzidau http://flybase.net/reports/FBgn0011566.html FBgn0029628 protein_coding_gene "0008270=zinc ion binding, 0003743=translation initiation factor activity" 0006413=translational initiation "EG:BACR7C10.4, CG13761, unnamed" "IPR002893=Zinc finger, MYND-type" CG13761 16-Dec-15 2015_12 "ENSDARG00000058050(smyd3),ENSDARG00000005629(smyd2b),ENSDARG00000055151(smyd2a),ENSDARG00000058549(smyd1b),ENSDARG00000009280(smyd1a)" WBGene00044070(set-18) "ENSXETG00000001940(SMYD1),ENSXETG00000023175(SMYD2)" ENSMUSG00000055067(Smyd3) ENSG00000185420(SMYD3) FBgn0065769 l(2)SH0467 lethal (2) SH0467 http://flybase.net/reports/FBgn0065769.html gene l(2)SH2 0467 16-Dec-15 2015_12 "lethal,recessive" FBgn0016946 tilC touch insensitive larva C http://flybase.net/reports/FBgn0016946.html gene 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0034221 CG10764 http://flybase.net/reports/FBgn0034221.html FBgn0028652 protein_coding_gene 0004252=serine-type endopeptidase activity "0035207=negative regulation of hemocyte proliferation, 0006508=proteolysis" "SP77, FBgn0034221, anon-54Ba, gene 2, GENE 2" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG10764 16-Dec-15 2015_12 ENSDARG00000051929 "viable,visible" trichogen cell FBgn0050333 tRNA:CR30333 transfer RNA:CR30333 http://flybase.net/reports/FBgn0050333.html "FBgn0050230, FBgn0060230" tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002787.trna11-PheGAA, chr2R.trna69-PheGAA, tRNA:F:GAA:AE002787-a, CR30230, CR30333" CR30333 16-Dec-15 2015_12 FBgn0038830 CG17272 http://flybase.net/reports/FBgn0038830.html FBgn0043804 protein_coding_gene 0005509=calcium ion binding BEST:GH27755 "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG17272 16-Dec-15 2015_12 viable FBgn0036882 CG9279 http://flybase.net/reports/FBgn0036882.html protein_coding_gene 0045502=dynein binding "0010970=microtubule-based transport, 0007018=microtubule-based movement" 0005869=dynactin complex "IPR027663=Dynactin subunit 1, IPR022157=Dynein associated protein, IPR000938=CAP Gly-rich domain" CG9279 16-Dec-15 2015_12 YPL174C(NIP100) WBGene00001017(dnc-1) viable FBgn0261801 CG42747 http://flybase.net/reports/FBgn0261801.html "FBgn0035700, FBgn0035701" protein_coding_gene "CG14910, CG14911" CG42747 16-Dec-15 2015_12 FBgn0004362 HmgD High mobility group protein D http://flybase.net/reports/FBgn0004362.html protein_coding_gene "0003677=DNA binding, 0003680=AT DNA binding, 0008301=DNA binding, bending" "0048813=dendrite morphogenesis, 0006325=chromatin organization, 0007517=muscle organ development" "0000790=nuclear chromatin, 0005634=nucleus" "clone 1.9, dHMG-D, HMG D, HMG1, hmg-D, hmgd, Dm-HMG-D100, anon-EST:Liang-1.9, HMGD, HMG-D100, Hmg-D, CG17950, HMG-D" IPR009071=High mobility group box domain CG17950 16-Dec-15 2015_12 "YMR072W(ABF2),YPR052C(NHP6A),YBR089C-A(NHP6B)" WBGene00001971(hmg-1.1) " adult stage | female , embryonic stage | stage 11-15 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-6 , embryonic stage | stage 9-16 , embryonic stage | early , adult stage && oogenesis stage | stage S1-14 , embryonic stage , embryonic stage | stage >=9 " " embryonic peripheral nervous system | restricted

, germarium

, embryonic central nervous system

,

ubiquitous , nurse cell

, follicle cell

, neuroblast

" embryonic stage -- adult stage "learning defective,viable,partially lethal - majority live,lethal - all die before end of pupal stage,majority die during larval stage,some die during pupal stage,fertile,lethal - all die before end of P-stage,some die during P-stage,lethal,body color defective" "rhabdomere R7,mesothoracic tergum" FBgn0035475 CG10866 http://flybase.net/reports/FBgn0035475.html protein_coding_gene IPR026572=Transmembrane protein C5orf28-like CG10866 16-Dec-15 2015_12 ENSDARG00000000142(si:busm1-79m10.4) ENSXETG00000016590(C5orf28) ENSMUSG00000074634(Gm7120) ENSG00000151881(C5orf28) "viable,fertile" FBgn0066358 l(2)214 lethal (2) 214 http://flybase.net/reports/FBgn0066358.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0260628 d11677 http://flybase.net/reports/FBgn0260628.html gene 16-Dec-15 2015_12 visible wing FBgn0060643 l(3)S084015b lethal (3) S084015b http://flybase.net/reports/FBgn0060643.html gene 0840/15 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0002729 mfs(2)350 male female sterile 350 http://flybase.net/reports/FBgn0002729.html gene str(2)350 16-Dec-15 2015_12 "female sterile,recessive,male sterile" "ovary,testis,spermatozoon" FBgn0264353 CR43809 http://flybase.net/reports/FBgn0264353.html non_protein_coding_gene CR43809 16-Dec-15 2015_12 FBgn0001886 l(2)21Bd lethal (2) 21Bd http://flybase.net/reports/FBgn0001886.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060823 l(3)S052001 lethal (3) S052001 http://flybase.net/reports/FBgn0060823.html gene 0520/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0082685 E(ftz)2142 E(ftz)2142 http://flybase.net/reports/FBgn0082685.html gene 2142 16-Dec-15 2015_12 FBgn0070017 BG01095 BG01095 http://flybase.net/reports/FBgn0070017.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "stress response defective,viable,smell perception defective" FBgn0002952 nofF no object fixation F http://flybase.net/reports/FBgn0002952.html gene 16-Dec-15 2015_12 "visual behavior defective,recessive" FBgn0000650 febA feeding behavior A http://flybase.net/reports/FBgn0000650.html gene 16-Dec-15 2015_12 "visible,behavior defective,recessive" FBgn0005456 l(1)v453 lethal (1) v453 http://flybase.net/reports/FBgn0005456.html gene l(1)453 16-Dec-15 2015_12 FBgn0262351 CG43049 http://flybase.net/reports/FBgn0262351.html protein_coding_gene CG43049 16-Dec-15 2015_12 FBgn0062692 EP1340 EP1340 http://flybase.net/reports/FBgn0062692.html gene EP(X)1340 16-Dec-15 2015_12 FBgn0000506 dsx-c50F doublesex cognate 50F http://flybase.net/reports/FBgn0000506.html gene dsx-c50 16-Dec-15 2015_12 FBgn0004024 ws waisted http://flybase.net/reports/FBgn0004024.html gene 16-Dec-15 2015_12 "visible,recessive,viable,poor" "adult abdomen,wing" FBgn0003985 Vein-dominant Vein dominant http://flybase.net/reports/FBgn0003985.html gene "Vein-dominant, Vein, Vn" 16-Dec-15 2015_12 "lethal,recessive,small body" "wing vein L4,wing" FBgn0042637 l(2)37Co lethal (2) 37Co http://flybase.net/reports/FBgn0042637.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0034614 CG9752 http://flybase.net/reports/FBgn0034614.html protein_coding_gene "IPR019438=Potential Queuosine, Q, salvage protein family" CG9752 16-Dec-15 2015_12 "ENSDARG00000041372(zgc:136564),ENSDARG00000068117" WBGene00015702(C11D2.4) ENSXETG00000004152(BC091587.1) ENSG00000165118(C9orf64) viable FBgn0024873 l(2)k03906b lethal (2) k03906b http://flybase.net/reports/FBgn0024873.html gene l(2)k03906 16-Dec-15 2015_12 "lethal,recessive" FBgn0060953 l(3)S036401b lethal (3) S036401b http://flybase.net/reports/FBgn0060953.html gene 0364/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0025001 E(var)90 E(var)90 http://flybase.net/reports/FBgn0025001.html gene E-90 16-Dec-15 2015_12 FBgn0013625 l(3)neo16 lethal (3) neo16 http://flybase.net/reports/FBgn0013625.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011155 l(1)Q233 lethal (1) Q233 http://flybase.net/reports/FBgn0011155.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0032283 CG7296 http://flybase.net/reports/FBgn0032283.html FBgn0061368 protein_coding_gene BcDNA:RH68528 CG7296 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" DRSC25754 K -0.036612709 -0.098074922 -0.055544649 -0.062876098 1.714408604 1.612904007 FBgn0010904 l(3)06906 lethal (3) 06906 http://flybase.net/reports/FBgn0010904.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000324 clm clumpy marginals http://flybase.net/reports/FBgn0000324.html gene 16-Dec-15 2015_12 "male fertile,fertile,female,reduced,viable,male,visible,recessive,female fertile" "macrochaeta,dorsal double row,ventral triple row,wing sensillum" FBgn0051176 CG31176 http://flybase.net/reports/FBgn0051176.html "FBgn0038895, FBgn0038896, FBgn0044453" protein_coding_gene "unnamed, EP(3)3662, EP3662, RE56061, CG6328, CG15495" CG31176 16-Dec-15 2015_12 viable "intersegmental nerve,germline cell,male" FBgn0027949 msb1l msb1l http://flybase.net/reports/FBgn0027949.html protein_coding_gene "msh1l, Msb1l, CG10364" CG10364 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0264940 CR44109 http://flybase.net/reports/FBgn0264940.html non_protein_coding_gene CR44109 16-Dec-15 2015_12 FBgn0029854 CG3566 http://flybase.net/reports/FBgn0029854.html FBgn0047011 protein_coding_gene 0009055=electron carrier activity 0005739=mitochondrion BcDNA:RH45308 IPR001199=Cytochrome b5-like heme/steroid binding domain CG3566 16-Dec-15 2015_12 YNL111C(CYB5) FBgn0052098 CG32098 http://flybase.net/reports/FBgn0052098.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264543 CG43922 http://flybase.net/reports/FBgn0264543.html protein_coding_gene CG43922 16-Dec-15 2015_12 FBgn0038803 CG5191 http://flybase.net/reports/FBgn0038803.html protein_coding_gene 0050567=glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity "IPR023631=Amidase signature domain, IPR000120=Amidase" CG5191 16-Dec-15 2015_12 YDR242W(AMD2) ENSMUSG00000034171(Faah) "viable,fertile" DRSC21559 E 1.492398459 1.173498091 1.868831465 -0.209582081 -0.085080681 0.85471704 FBgn0261603 M(2)60B Minute (2) 60B http://flybase.net/reports/FBgn0261603.html gene 16-Dec-15 2015_12 FBgn0038488 m-cup mann-cup http://flybase.net/reports/FBgn0038488.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0016567=protein ubiquitination "mann-cup, CG11896, m-cup" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG11896 16-Dec-15 2015_12 viable FBgn0035431 CG14968 http://flybase.net/reports/FBgn0035431.html "FBgn0043957, FBgn0043958, FBgn0043960" protein_coding_gene "anon-WO0107627.2, anon-WO0107627.1, anon-WO0107627.3" "IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG14968 16-Dec-15 2015_12 "ENSDARG00000039750(ldlrap1b),ENSDARG00000004311(ldlrap1a),ENSDARG00000043394" ENSMUSG00000037295(Ldlrap1) viable FBgn0029180 E(Khc)ek7 E(Khc)ek7 http://flybase.net/reports/FBgn0029180.html gene 16-Dec-15 2015_12 FBgn0021821 l(2)k16210 lethal (2) k16210 http://flybase.net/reports/FBgn0021821.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260360 GSd231 http://flybase.net/reports/FBgn0260360.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0263264 com1 http://flybase.net/reports/FBgn0263264.html gene 0008406=gonad development compaction defects 1 16-Dec-15 2015_12 gonad FBgn0085772 CR40743 http://flybase.net/reports/FBgn0085772.html FBan0040743 rRNA_gene CR40743 16-Dec-15 2015_12 FBgn0262172 mir-307b mir-307b stem loop http://flybase.net/reports/FBgn0262172.html miRNA_gene "Dme-mir-307-as, miR-307b, mir-307-as, miR-307-AS, CR42879, mir-307-as stem loop, miR-307, mir-307" CR42879 16-Dec-15 2015_12 viable FBgn0035309 CG15879 http://flybase.net/reports/FBgn0035309.html protein_coding_gene "IPR000073=Alpha/beta hydrolase fold-1, IPR029058=Alpha/Beta hydrolase fold" CG15879 16-Dec-15 2015_12 "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" "ENSG00000183569(SERHL2),ENSG00000172250" viable FBgn0000733 fs(1)42 female sterile (1) 42 http://flybase.net/reports/FBgn0000733.html gene 16-Dec-15 2015_12 "female sterile,viable" "follicle cell,egg chamber,germarium,cystocyte" FBgn0051998 CG31998 http://flybase.net/reports/FBgn0051998.html "FBgn0039891, FBgn0039892" protein_coding_gene "CG11572, CG11578" CG31998 16-Dec-15 2015_12 viable FBgn0011782 l(2)rL220 lethal (2) rL220 http://flybase.net/reports/FBgn0011782.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001552 l(1)19Aa lethal (1) 19Aa http://flybase.net/reports/FBgn0001552.html gene "EM18, l(1)EM18" 16-Dec-15 2015_12 lethal FBgn0031178 CG10918 http://flybase.net/reports/FBgn0031178.html protein_coding_gene 0005615=extracellular space CG10918 16-Dec-15 2015_12 viable FBgn0025759 l(3)93DFc lethal (3) 93DFc http://flybase.net/reports/FBgn0025759.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0044109 E(rst)C383 E(rst)C383 http://flybase.net/reports/FBgn0044109.html gene 0001745=compound eye morphogenesis C383 16-Dec-15 2015_12 viable FBgn0065081 snmRNA:838 small non-messenger RNA 838 http://flybase.net/reports/FBgn0065081.html FBgn0053793 non_protein_coding_gene "CR33793, Dm-838" CR33793 16-Dec-15 2015_12 FBgn0015550 tap target of Poxn http://flybase.net/reports/FBgn0015550.html "FBgn0010757, FBgn0019837" protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0007423=sensory organ development" 0005634=nucleus "CG7659, target of poxn, Tap, biparous, bps, target of Pox-n, bHLHc9, l(3)01658" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG7659 16-Dec-15 2015_12 "ENSDARG00000019566(neurod),ENSDARG00000003469(neurod4),ENSDARG00000016854(neurod2),ENSDARG00000040008(atoh2a),ENSDARG00000020794(atoh2b)" WBGene00000561(cnd-1) "ENSMUSG00000048015(Neurod4),ENSMUSG00000034701(Neurod1),ENSMUSG00000038255(Neurod2),ENSMUSG00000037984(Neurod6)" " embryonic stage | stage 10,11 , embryonic stage | stage 10-15 , embryonic stage , embryonic stage | stage 11 " " neuroblast NB4-1

, ventral nerve cord | restricted

, embryonic peripheral nervous system | restricted

, embryonic nervous system | restricted

, embryonic ganglion mother cell

, neuroblast

" embryonic stage v'es2 neuron

"lethal,recessive,tarsal response defective,heat sensitive,viable" DRSC11402 E -0.184161504 0.776995246 0.937501796 -1.548536604 -0.846422776 0.935052817 FBgn0034277 OstëÓ Oligosaccharide transferase ëÓ subunit http://flybase.net/reports/FBgn0034277.html protein_coding_gene 0004579=dolichyl-diphosphooligosaccharide-protein glycotransferase activity "0006487=protein N-linked glycosylation, 0035010=encapsulation of foreign target" "0016021=integral component of membrane, 0012505=endomembrane system, 0008250=oligosaccharyltransferase complex" "CG6370, OST" IPR008814=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 CG6370 16-Dec-15 2015_12 ENSXETG00000017317(rpn2) ENSMUSG00000027642(Rpn2) ENSG00000118705(RPN2) "viable,immune response defective" FBgn0010544 l(2)03563 lethal (2) 03563 http://flybase.net/reports/FBgn0010544.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259479 EP-553 http://flybase.net/reports/FBgn0259479.html gene 16-Dec-15 2015_12 visible "wing,wing vein,wing margin,chaeta,ectopic" FBgn0021966 l(2)k10103 lethal (2) k10103 http://flybase.net/reports/FBgn0021966.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030479 Rbp1-like Rbp1-like http://flybase.net/reports/FBgn0030479.html "FBgn0063004, FBgn0069063" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding" "0031440=regulation of mRNA 3'-end processing, 0000398=mRNA splicing, via spliceosome, 0008380=RNA splicing, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0006376=mRNA splice site selection, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0010468=regulation of gene expression" "0071011=precatalytic spliceosome, 0005681=spliceosomal complex" "i159, CG1987, BcDNA:RE47308, BEST:HL02433, Rbp1L, RBP1-like" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG1987 16-Dec-15 2015_12 "ENSDARG00000025397(sfrs3a),ENSDARG00000059360(sfrs3b)" "ENSMUSG00000078134,ENSMUSG00000071172(Srsf3)" "viable,fertile" FBgn0050169 Brca2 "Breast cancer 2, early onset homolog" http://flybase.net/reports/FBgn0050169.html "FBgn0035017, FBgn0035018, FBgn0062848" protein_coding_gene 0005515=protein binding "0000724=double-strand break repair via homologous recombination, 0051598=meiotic recombination checkpoint, 1901563=response to camptothecin, 0006974=cellular response to DNA damage stimulus, 0006281=DNA repair" 0005634=nucleus "Dmbrca2, CG30169, CG13583, dmbrca2, CG13584, BcDNA:SD25109, Breast cancer 2 early onset homolog, BRCA2, brca2, 30169" IPR002093=BRCA2 repeat CG30169 16-Dec-15 2015_12 "chemical sensitive,female sterile,viable,radiation sensitive,DNA repair defective,recessive" "karyosome,dorsal appendage,maternal effect" FBgn0024854 ltwt lightweight http://flybase.net/reports/FBgn0024854.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0050362 boly borrelly http://flybase.net/reports/FBgn0050362.html "FBgn0033284, FBgn0063902" protein_coding_gene "borrelly, CG2149, NEST:bs34d07, CG30362, boly" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30362 16-Dec-15 2015_12 viable FBgn0051242 tRNA:CR31242 transfer RNA:CR31242 http://flybase.net/reports/FBgn0051242.html "FBgn0011875, FBgn0060210" tRNA_gene "0033463=GGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:gly:90DE, tRNA:G:90DE, chr3R.trna24-GlyTCC, CR31242, tRNA[Gly][[GGA]], tRNA:G:TCC:AE002708-a, tRNA:gly:90DE, AE002708.trna18-GlyTCC" CR31242 16-Dec-15 2015_12 FBgn0010309 pigeon pigeon http://flybase.net/reports/FBgn0010309.html protein_coding_gene "lio, pio, CG10739, unnamed, linotte, lionette" "IPR026172=Gamma-secretase-activating protein family, IPR028010=Gamma-secretase-activating protein, C-terminal domain" CG10739 16-Dec-15 2015_12 ENSDARG00000045481(pion) ENSMUSG00000039934(Pion) ENSG00000186088(PION) embryonic stage&&pupal stage&&adult stage "memory defective,learning defective,neuroanatomy defective,viable,recessive" synapse FBgn0019660 roX2 RNA on the X 2 http://flybase.net/reports/FBgn0019660.html FBgn0052665 non_protein_coding_gene "0035613=RNA stem-loop binding, 0005515=protein binding" "0009047=dosage compensation by hyperactivation of X chromosome, 0007549=dosage compensation, 0031936=negative regulation of chromatin silencing, 0016457=dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome" "0016456=X chromosome located dosage compensation complex, transcription activating, 0000805=X chromosome, 0072487=MSL complex" "rox2, rna on the x2, RNA on the X chromosome 2, roX, RNA on the X2, RoX2, CR32665" CR32665 16-Dec-15 2015_12 adult stage | male " optic lobe neuron

, cell body &&of mushroom body

, pupal/adult digestive system

, cell body &&of adult brain

, neuron &&of antennal segment 3

, interneuron &&of antennal lobe

, thoracico-abdominal ganglion

, photoreceptor cell

" FBgn0266833 CR45295 http://flybase.net/reports/FBgn0266833.html non_protein_coding_gene CR45295 16-Dec-15 2015_12 FBgn0262393 mir-33 mir-33 stem loop http://flybase.net/reports/FBgn0262393.html "FBgn0067683, FBgn0262221" miRNA_gene "33, miR-33, dme-mir-33, CR42928, CR33569, mir-33, miR33" CR42928 16-Dec-15 2015_12 viable FBgn0001859 l(1)TW4 lethal (1) TW4 http://flybase.net/reports/FBgn0001859.html gene 16-Dec-15 2015_12 "visible,lethal,cold sensitive,female fertile" metathoracic leg FBgn0060849 l(3)S048606a lethal (3) S048606a http://flybase.net/reports/FBgn0060849.html gene 0486/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0264273 Sema-2b Semaphorin-2b http://flybase.net/reports/FBgn0264273.html "FBgn0026363, FBgn0053960, FBgn0034125, FBgn0050322, FBtr0087155, FBpp0086299, FBtr0087156, FBpp0086300" protein_coding_gene "2001020=regulation of response to DNA damage stimulus, 0071678=olfactory bulb axon guidance, 0007411=axon guidance, 0070983=dendrite guidance, 0016200=synaptic target attraction" "0005576=extracellular region, 0005886=plasma membrane" "SemaIIB, semiphorin, CG33960, Sema2b, CG4383, sema-2b, semaphorin2b, Sema-2b, CG30322, semaphorin" "IPR027231=Semaphorin, IPR001627=Sema domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG33960 16-Dec-15 2015_12 WBGene00003111(mab-20) "ENSXETG00000018720(SEMA6A),ENSXETG00000010843(SEMA4D),ENSXETG00000018391(SEMA6D),ENSXETG00000005837(SEMA6C),ENSXETG00000012967(SEMA4B),ENSXETG00000001251(SEMA4C),ENSXETG00000015209(SEMA4G),ENSXETG00000018164(SEMA4A)" FBgn0024850 mus114 mus114 http://flybase.net/reports/FBgn0024850.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0002041 l(2)37De lethal (2) 37De http://flybase.net/reports/FBgn0002041.html gene "l(2)OE70, OE30, l(2)OE30" 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,cold sensitive" "eye,wing" FBgn0037179 CG14453 http://flybase.net/reports/FBgn0037179.html FBgn0063060 protein_coding_gene BcDNA:RE13473 CG14453 16-Dec-15 2015_12 DRSC11710 I -2.074409373 0.111902553 -0.899454941 0.863838407 -0.382998361 -0.571448675 FBgn0004979 bal bandy legged http://flybase.net/reports/FBgn0004979.html gene 16-Dec-15 2015_12 "visible,recessive,fertile,locomotor behavior defective" leg FBgn0038018 Tim17a1 Tim17a1 http://flybase.net/reports/FBgn0038018.html protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0006626=protein targeting to mitochondrion 0005744=mitochondrial inner membrane presequence translocase complex CG10090 "IPR005678=Mitochondrial inner membrane translocase complex, subunit Tim17, IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24" CG10090 16-Dec-15 2015_12 YJL143W(TIM17) WBGene00017119(E04A4.5) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0039438 TwdlO TweedleO http://flybase.net/reports/FBgn0039438.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix CG6452 IPR004145=Domain of unknown function DUF243 CG6452 16-Dec-15 2015_12 viable DRSC16043 IK 2.770013037 0.149993388 -0.275530227 0.148699782 -0.48653355 1.845498599 FBgn0261003 Qajjem Qajjem http://flybase.net/reports/FBgn0261003.html gene AGAR-211 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0010686 l(2)s2978 lethal (2) s2978 http://flybase.net/reports/FBgn0010686.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0082618 S(CycEJP)59S9 S(CycEJP)59S9 http://flybase.net/reports/FBgn0082618.html gene 59S9 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0260359 GSd458 http://flybase.net/reports/FBgn0260359.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "longitudinal connective,ventral nerve cord" FBgn0011272 RpL13 Ribosomal protein L13 http://flybase.net/reports/FBgn0011272.html "FBgn0014460, FBgn0025260" protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0051298=centrosome duplication, 0000022=mitotic spindle elongation" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "Rp L13, bbc1, rpL13, r-protein L13, Rpl13, Dmbbc1, CG4651, L13, unnamed, anon-fast-evolving-1D1, Bbc1, anon-EST:fe1D1" "IPR018256=Ribosomal protein L13e, conserved site, IPR001380=Ribosomal protein L13e" CG4651 16-Dec-15 2015_12 ENSDARG00000030585(rpl13) "YDL082W(RPL13A),YMR142C(RPL13B)" WBGene00004425(rpl-13) ENSXETG00000019835(rpl13) "ENSMUSG00000000740(Rpl13),ENSMUSG00000059835(Rpl13-ps3),ENSMUSG00000059776(Gm10071)" ENSG00000167526(RPL13) embryonic stage -- adult stage DRSC03416 IEK 0.002462202 -1.757895438 -1.21735038 -4.387297988 1.649225565 6.38262367 FBgn0001533 l(1)14Aa lethal (1) 14Aa http://flybase.net/reports/FBgn0001533.html gene h26a 16-Dec-15 2015_12 lethal FBgn0005202 l(3)blo-l lethal bloated larvae http://flybase.net/reports/FBgn0005202.html gene lethal (3) bloated larvae 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" imaginal disc FBgn0002424 l(3)F23 lethal (3) F23 http://flybase.net/reports/FBgn0002424.html gene l(3)23 16-Dec-15 2015_12 "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033787 CG13321 http://flybase.net/reports/FBgn0033787.html protein_coding_gene 0022008=neurogenesis "IPR024518=Domain of unknown function DUF3421, IPR006616=DM9 repeat" CG13321 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0040900 CG17777 http://flybase.net/reports/FBgn0040900.html protein_coding_gene CG17777 16-Dec-15 2015_12 viable FBgn0039298 to takeout http://flybase.net/reports/FBgn0039298.html protein_coding_gene "0007631=feeding behavior, 0008049=male courtship behavior, 0042594=response to starvation, 0007623=circadian rhythm, 0007622=rhythmic behavior, 0007617=mating behavior, 0042595=behavioral response to starvation, 0008343=adult feeding behavior" "0005576=extracellular region, 0005615=extracellular space" "CT33074, CG11853, Takeout, take-out, To" IPR010562=Haemolymph juvenile hormone binding CG11853 16-Dec-15 2015_12 "viable,fertile,circadian rhythm defective,partially lethal - majority live,feeding behavior defective" DRSC17086 E -0.886431929 0.010562298 -1.143400024 3.411191939 0.12695303 0.532644545 FBgn0087021 Spc25 Spc25 http://flybase.net/reports/FBgn0087021.html "FBgn0002349, FBgn0040494, FBgn0038094, FBgn0069190" protein_coding_gene "0007080=mitotic metaphase plate congression, 0007059=chromosome segregation, 0007052=mitotic spindle organization" "0000776=kinetochore, 0031262=Ndc80 complex" "BcDNA:LD37196, dmSpc25R, Mitch, l(3)A34-1, cal2, unnamed, Cal2, lethal (3) c00064, l(3)S3, lethal (3) 87Da, l(3)A46-1, l(3)c00064, mitch, CG7242, l(3)87Da, mitotic chaos, chromosome alignment defect 2, S3" CG7242 16-Dec-15 2015_12 FBgn0053539 tRNA:CR33539 transfer RNA:CR33539 http://flybase.net/reports/FBgn0053539.html FBgn0060016 tRNA_gene "0033416=UGG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR33539, chr2R.trna46-TrpCCA, tRNA:W:CCA:AE002575-b, AE002575.trna2-TrpCCA" CR33539 16-Dec-15 2015_12 FBgn0024650 l(2)k09208 lethal (2) k09208 http://flybase.net/reports/FBgn0024650.html gene 92/8 16-Dec-15 2015_12 "lethal,recessive" FBgn0065733 l(2)SH0549 lethal (2) SH0549 http://flybase.net/reports/FBgn0065733.html gene l(2)SH2 0549 16-Dec-15 2015_12 "lethal,recessive" FBgn0043595 E(roDOM)1801 E(roDOM)1801 http://flybase.net/reports/FBgn0043595.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0030120 CG17440 http://flybase.net/reports/FBgn0030120.html protein_coding_gene 0008270=zinc ion binding "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR019787=Zinc finger, PHD-finger, IPR001965=Zinc finger, PHD-type" CG17440 16-Dec-15 2015_12 YPL138C(SPP1) FBgn0062651 EP382 EP382 http://flybase.net/reports/FBgn0062651.html gene EP(X)0382 16-Dec-15 2015_12 FBgn0011578 ded depleted http://flybase.net/reports/FBgn0011578.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 "lethal,recessive" "external sensory organ,chordotonal organ,multidendritic neuron" FBgn0036591 CG13050 http://flybase.net/reports/FBgn0036591.html protein_coding_gene CG13050 16-Dec-15 2015_12 viable DRSC09931 K 0.363376552 1.170282247 1.288011069 0.153139876 0.739703488 1.58104468 FBgn0001824 l(1)trs lethal (1) tracheae stretched http://flybase.net/reports/FBgn0001824.html gene l(1)ts 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0085432 pan pangolin http://flybase.net/reports/FBgn0085432.html "FBgn0022393, FBgn0052005, FBgn0019664" protein_coding_gene "0019900=kinase binding, 0005515=protein binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0070491=repressing transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0008013=beta-catenin binding" "0010628=positive regulation of gene expression, 0072091=regulation of stem cell proliferation, 0007476=imaginal disc-derived wing morphogenesis, 0030111=regulation of Wnt signaling pathway, 0007507=heart development, 0007500=mesodermal cell fate determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0016055=Wnt signaling pathway, 0035277=spiracle morphogenesis, open tracheal system, 0045610=regulation of hemocyte differentiation, 0006355=regulation of transcription, DNA-templated, 0009880=embryonic pattern specification, 0060070=canonical Wnt signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter, 0045893=positive regulation of transcription, DNA-templated, 0007367=segment polarity determination, 0030178=negative regulation of Wnt signaling pathway, 0007435=salivary gland morphogenesis" "0005875=microtubule associated complex, 0005667=transcription factor complex, 0005634=nucleus" "PAN, lef1, CG17964, Pangolin, l(4)102ABb, lymphocyte enhancer binding factor 1/T cell factor, DTCF, l(4)13, TCF, Tcf, Lef1, d-TCF, unnamed, T cell factor, IA5, pan.dTCF, tcf, Lef, Tcf/LEF, LEF-1, DTcf, LEF1/TCF, dTCF, pangolin, lethal 13, CG32005, LEF/TCF-1, Tcf-1, Pan, CG34403, Dm Pan, TCF/LEF1, TCF/LEF, T-cell factor, LEF1, LEF/TCF, cTCF, dTcf" "IPR024940=Transcription factor TCF/LEF, IPR009071=High mobility group box domain, IPR028782=Protein pangolin, IPR027397=Catenin binding domain, IPR013558=CTNNB1 binding, N-teminal" CG34403 16-Dec-15 2015_12 " embryonic stage | stage 13 , embryonic stage | early , embryonic stage | 0-2hr , embryonic stage | stage 7 , embryonic stage " " procephalic segment

,

ubiquitous , visceral mesoderm

" FBgn0000239 bur burgundy http://flybase.net/reports/FBgn0000239.html "FBgn0010666, FBgn0032928, FBgn0062173, FBgn0062180" protein_coding_gene "0003921=GMP synthase activity, 0016462=pyrophosphatase activity, 0005524=ATP binding, 0003922=GMP synthase (glutamine-hydrolyzing) activity, 0035800=deubiquitinase activator activity" "2000152=regulation of ubiquitin-specific protease activity, 0006177=GMP biosynthetic process, 0007411=axon guidance, 0016578=histone deubiquitination" "0043234=protein complex, 0005700=polytene chromosome" "P174, gua2, l(2)10523, Enhancer of GMR-sina 2-2, Gmps, GMP synthetase, ES2-2, anon-WO0118547.204, GMPS, CG9242, anon-WO0118547.193" "IPR004739=GMP synthase, N-terminal, IPR001674=GMP synthase, C-terminal, IPR025777=GMP synthetase ATP pyrophosphatase domain, IPR017926=Glutamine amidotransferase, IPR022310=NAD/GMP synthase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR029062=Class I glutamine amidotransferase-like" CG9242 16-Dec-15 2015_12 YMR217W(GUA1) WBGene00010912(M106.4) ENSMUSG00000027823(Gmps) ENSG00000163655(GMPS) "lethal,recessive,neuroanatomy defective,visible,viable,eye color defective,female fertile,good,male fertile,partially,lethal - all die before end of pupal stage,some die during pupal stage,auxotroph" "lamina,medulla,photoreceptor cell R7 & growth cone,photoreceptor cell R8 & growth cone,photoreceptor cell & axon,photoreceptor cell & axon | somatic clone | cell autonomous,pigment cell" FBgn0065361 l(2)SH1744 lethal (2) SH1744 http://flybase.net/reports/FBgn0065361.html gene l(2)SH2 1744 16-Dec-15 2015_12 "lethal,recessive" FBgn0010462 l(2)00329 lethal (2) 00329 http://flybase.net/reports/FBgn0010462.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260065 2L3908 http://flybase.net/reports/FBgn0260065.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0019918 TrlBR Trithorax-like Binding Region http://flybase.net/reports/FBgn0019918.html engineered_region "GAGA element, unnamed" 16-Dec-15 2015_12 FBgn0010088 Su(Dl)F116 Suppressor of Delta F116 http://flybase.net/reports/FBgn0010088.html gene 16-Dec-15 2015_12 FBgn0001793 l(1)Mb24 lethal (1) Mb24 http://flybase.net/reports/FBgn0001793.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,wing hair" FBgn0029940 CG1958 http://flybase.net/reports/FBgn0029940.html protein_coding_gene CG1958 16-Dec-15 2015_12 viable FBgn0034826 CG13544 http://flybase.net/reports/FBgn0034826.html protein_coding_gene 0032027=myosin light chain binding "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000048=IQ motif, EF-hand binding site" CG13544 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0266812 CR45274 http://flybase.net/reports/FBgn0266812.html non_protein_coding_gene CR45274 16-Dec-15 2015_12 FBgn0051885 tRNA:CR31885 transfer RNA:CR31885 http://flybase.net/reports/FBgn0051885.html FBgn0060049 tRNA_gene 0033437=ACU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA[[Thr]], tRNA:T:AGT:AE002690, AE002690.trna20-ThrAGT, chr2L.trna29-ThrAGT, CR31885" CR31885 16-Dec-15 2015_12 FBgn0264802 l(3)64Ab lethal (3) 64Ab http://flybase.net/reports/FBgn0264802.html "FBgn0014283, FBgn0027980" gene "l(3)SH15, 1372/12, l(3)S137212, l(3)SH19, lethal (3) S137212" 16-Dec-15 2015_12 FBgn0063496 GstE4 Glutathione S transferase E4 http://flybase.net/reports/FBgn0063496.html FBgn0034338 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GSTE4, CG17525, DmGSTE4, gste4" "IPR004046=Glutathione S-transferase, C-terminal, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like" CG17525 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0038781 CG10883 http://flybase.net/reports/FBgn0038781.html protein_coding_gene 0016246=RNA interference 16-Dec-15 2015_12 FBgn0038242 CG14852 http://flybase.net/reports/FBgn0038242.html protein_coding_gene CG14852 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0263000 CG43308 http://flybase.net/reports/FBgn0263000.html protein_coding_gene CG43308 16-Dec-15 2015_12 FBgn0025154 ms(2)A2 ms(2)A2 http://flybase.net/reports/FBgn0025154.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0022324 l(1)B10.2 lethal (1) B10.2 http://flybase.net/reports/FBgn0022324.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083271 E(smoDN)2619 Enhancer of smoDN 2619 http://flybase.net/reports/FBgn0083271.html gene 16-Dec-15 2015_12 FBgn0038063 Octë_2R Octopamine ë_2 receptor http://flybase.net/reports/FBgn0038063.html "FBgn0038064, FBgn0046561, FBgn0046562, FBgn0053976, FBtr0082672, FBpp0082141, FBtr0082673, FBpp0082142" protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0004989=octopamine receptor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0045887=positive regulation of synaptic growth at neuromuscular junction" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "Octbeta2r, CG18553, DmCG6989, CG33976, anon-WO0170980.184, Dm_3R:45121, octopamine beta receptor, octbeta2R, Octbeta2R, anon-WO0170980.185, DmOctbeta2R, CG6989, OctBeta2, OctB2R" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR004827=Basic-leucine zipper domain" CG33976 16-Dec-15 2015_12 "viable,fertile,neurophysiology defective,starvation stress response defective,neuroanatomy defective,recessive,locomotor behavior defective,sleep defective" "multidendritic neuron,type I bouton,embryonic/larval neuromuscular junction,type II bouton,type II bouton | third instar larval stage,type I bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" DRSC15350 EK -1.345375621 -1.209757201 -1.513269668 -1.57090047 -0.52333574 -1.666490362 FBgn0025156 ms(2)A11 ms(2)A11 http://flybase.net/reports/FBgn0025156.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0040328 EY3-3 EY3-3 http://flybase.net/reports/FBgn0040328.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265352 Myo31DF::Myo61F http://flybase.net/reports/FBgn0265352.html engineered_fusion_gene 16-Dec-15 2015_12 axis specification defective "embryonic foregut,embryonic/larval midgut,embryonic hindgut" FBgn0061144 l(3)S000417c lethal (3) S000417c http://flybase.net/reports/FBgn0061144.html gene 17-Apr 16-Dec-15 2015_12 "lethal,recessive" FBgn0050293 Cht12 Cht12 http://flybase.net/reports/FBgn0050293.html "FBgn0045113, FBgn0045151, FBgn0045348, FBgn0063725" protein_coding_gene "0008061=chitin binding, 0004568=chitinase activity" "0005975=carbohydrate metabolic process, 0006030=chitin metabolic process, 0006032=chitin catabolic process" 0005576=extracellular region "CG30293, BcDNA:AT18578, NEST:bs28h08, NEST:bs33a06, NEST:bs09g08" "IPR002557=Chitin binding domain, IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain, IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain" CG30293 16-Dec-15 2015_12 YDR371W(CTS2) viable FBgn0039736 CG7912 http://flybase.net/reports/FBgn0039736.html "FBtr0085605, FBpp0084970" protein_coding_gene 0015381=high-affinity sulfate transmembrane transporter activity "0008272=sulfate transport, 0055085=transmembrane transport" 0016021=integral component of membrane "IPR011547=SLC26A/SulP transporter domain, IPR001902=SLC26A/SulP transporter, IPR002645=STAS domain" CG7912 16-Dec-15 2015_12 ENSDARG00000043021(slc26a11) "YLR092W(SUL2),YBR294W(SUL1)" ENSMUSG00000039908(Slc26a11) ENSG00000181045(SLC26A11) viable DRSC16343 I -0.465041155 3.983932896 -0.625800513 0.037061871 -0.689923135 0.530643942 FBgn0061360 CG33672 http://flybase.net/reports/FBgn0061360.html "FBgn0033758, FBgn0033759, FBgn0053009, FBgn0053672, FBtr0087883, FBtr0087884, FBpp0086997" protein_coding_gene "CG8810, CG33009, CG16804, CG16804a, Dromel_CG33672_FBtr0091651_uORF, CG33009-ORFA, CG33009ORFA" IPR002634=BolA protein CG33672 16-Dec-15 2015_12 YGL220W(FRA2) WBGene00023450(T12D8.10) ENSXETG00000012819() ENSMUSG00000047721(Bola2) "ENSG00000169627(BOLA2B),ENSG00000183336(BOLA2)" FBgn0033783 CG17019 http://flybase.net/reports/FBgn0033783.html protein_coding_gene 0008270=zinc ion binding "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type" CG17019 16-Dec-15 2015_12 "ENSDARG00000042833(LOC100332038),ENSDARG00000056244(zgc:171740),ENSDARG00000054036(zgc:171755)" "ENSXETG00000020965(RNF34),ENSXETG00000022465(Q5BL61_XENTR)" "ENSMUSG00000020696(Rffl),ENSMUSG00000029474(Rnf34)" "ENSG00000170633(RNF34),ENSG00000092871(RFFL)" viable FBgn0034518 CG13430 http://flybase.net/reports/FBgn0034518.html "FBgn0053008, FBtr0086260, FBpp0085572, FBtr0086261, FBpp0085573, FBtr0086262, FBpp0085574" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG33008, SP70" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG13430 16-Dec-15 2015_12 "ENSXETG00000000063(),ENSXETG00000005961(),ENSXETG00000027108(),ENSXETG00000027103()" ENSMUSG00000032091(Tmprss4) "ENSG00000137648(TMPRSS4),ENSG00000166682(TMPRSS5),ENSG00000105707(HPN)" FBgn0041224 Gr97a Gustatory receptor 97a http://flybase.net/reports/FBgn0041224.html "FBgn0051073, FBgn0051074, FBgn0053083" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG33083, gustatory receptor 97a, CG31074, Gustatory receptor 97D.1, GR97a, Gr97D1, 97D.1, GR97D.1, CG31073" IPR013604=7TM chemoreceptor CG33083 16-Dec-15 2015_12 "viable,fertile" FBgn0033202 CG1339 http://flybase.net/reports/FBgn0033202.html protein_coding_gene 0008527=taste receptor activity 0016021=integral component of membrane "Gr43b, mdcds_19638, CG1339" CG1339 16-Dec-15 2015_12 viable DRSC06383 E -0.844849574 -0.984651896 -1.849813775 0.859572038 -0.002863843 0.334049229 FBgn0016826 l(1)MZ13 lethal (1) MZ13 http://flybase.net/reports/FBgn0016826.html gene M13 16-Dec-15 2015_12 "lethal,recessive" FBgn0040395 Unc-76 Unc-76 http://flybase.net/reports/FBgn0040395.html "FBgn0026690, FBgn0027210, FBgn0027224, FBgn0028355, FBgn0029063, FBgn0029598, FBgn0042171, FBgn0047315" protein_coding_gene 0019894=kinesin binding "0006909=phagocytosis, 0008088=axon cargo transport, 0022008=neurogenesis" "UNC-76, unc-76, BcDNA:GH10260, EG:67A9.1, CG18851, l(1)G0333, l(1)G0360, Dunc-76, l(1)G0158, l(1)G0310, CG3981, l(1)G0066" "IPR011680=Fasciculation and elongation protein zeta, FEZ" CG3981 16-Dec-15 2015_12 ENSDARG00000022260(si:ch211-57i17.1) WBGene00006808(unc-76) "ENSXETG00000018513(fez2),ENSXETG00000017780(FEZ1)" "ENSMUSG00000056121(Fez2),ENSMUSG00000032118(Fez1)" "ENSG00000171055(FEZ2),ENSG00000149557(FEZ1)" "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,viable,fertile,paralytic,uncoordinated,neuroanatomy defective,visible" "third instar larva,axon,pupa,ganglion mother cell,chaeta,supernumerary" FBgn0027124 l(3)PG1-3 lethal (3) PG1-3 http://flybase.net/reports/FBgn0027124.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0001135 gre green body http://flybase.net/reports/FBgn0001135.html gene green body color 16-Dec-15 2015_12 "visible,recessive,body color defective" FBgn0263908 l(3)A41 http://flybase.net/reports/FBgn0263908.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0263871 CR43718 http://flybase.net/reports/FBgn0263871.html non_protein_coding_gene CR43718 16-Dec-15 2015_12 FBgn0053867 His-ë¬:CR33867 His-ë¬:CR33867 http://flybase.net/reports/FBgn0053867.html pseudogene_attribute "CR33867, His-Psi:CR33867" CR33867 16-Dec-15 2015_12 FBgn0028618 l(2)35Cg lethal (2) 35Cg http://flybase.net/reports/FBgn0028618.html gene 16-Dec-15 2015_12 FBgn0003009 ord orientation disruptor http://flybase.net/reports/FBgn0003009.html protein_coding_gene 0005515=protein binding "0007276=gamete generation, 0007062=sister chromatid cohesion, 0051177=meiotic sister chromatid cohesion, 0007060=male meiosis chromosome segregation, 0007067=mitotic nuclear division, 0007059=chromosome segregation, 0007065=male meiosis sister chromatid cohesion, 0007126=meiotic nuclear division, 0007066=female meiosis sister chromatid cohesion" "0001674=female germ cell nucleus, 0008278=cohesin complex, 0001673=male germ cell nucleus" "Orientation Disruptor, ORD, CG3134, orientation disrupter, Orientation disrupter, Ord, orientation disruptor" CG3134 16-Dec-15 2015_12 adult stage spermatocyte

"meiotic cell cycle defective,viable,female fertile,reduced,male,male sterile,partially,recessive,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,female sterile,male fertile" "nuclear chromosome3-70),cell cycle3-70),oocyte,meiosis & nuclear chromosome | male,meiotic cell cycle,nuclear chromosome | female,spermatocyte,cyst cell,male,testis,meiosis & nuclear chromosome3-70)" FBgn0023516 Pex5 Peroxin 5 http://flybase.net/reports/FBgn0023516.html protein_coding_gene "0005052=peroxisome matrix targeting signal-1 binding, 0000268=peroxisome targeting sequence binding" "0016560=protein import into peroxisome matrix, docking, 0072347=response to anesthetic, 0016558=protein import into peroxisome matrix, 0007031=peroxisome organization" "0005829=cytosol, 0005778=peroxisomal membrane, 0005777=peroxisome" "PEX5, EG:63B12.5, CG14815, DmelPex5" "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat, IPR024111=Peroxisomal targeting signal 1 receptor family, IPR001440=Tetratricopeptide repeat 1" CG14815 16-Dec-15 2015_12 "ENSDARG00000070654(pex5),ENSDARG00000070659" YDR244W(PEX5) WBGene00004194(prx-5) ENSXETG00000023910(pex5) ENSMUSG00000005069(Pex5) ENSG00000139197(PEX5) "chemical sensitive,recessive,viable" FBgn0085577 CG41251 http://flybase.net/reports/FBgn0085577.html FBan0041251 protein_coding_gene 16-Dec-15 2015_12 FBgn0082361 HM122 HM122 http://flybase.net/reports/FBgn0082361.html gene 16-Dec-15 2015_12 FBgn0010745 l(3)01344 lethal (3) 01344 http://flybase.net/reports/FBgn0010745.html gene l(3)1344 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0034029 eIF2B-ë_ eIF2B-ë_ http://flybase.net/reports/FBgn0034029.html protein_coding_gene "0003743=translation initiation factor activity, 0016779=nucleotidyltransferase activity" "0071456=cellular response to hypoxia, 0006413=translational initiation" "0005829=cytosol, 0005851=eukaryotic translation initiation factor 2B complex" "CG8190, eIF2B-gamma, eIF2Bgamma" "IPR005835=Nucleotidyl transferase domain, IPR029044=Nucleotide-diphospho-sugar transferases, IPR025877=MobA-like NTP transferase" CG8190 16-Dec-15 2015_12 ENSDARG00000018106(eif2b3) YOR260W(GCD1) WBGene00004090(ppp-1) ENSXETG00000018885(EIF2B3) ENSMUSG00000028683(Eif2b3) ENSG00000070785(EIF2B3) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0053213 CG33213 http://flybase.net/reports/FBgn0053213.html FBgn0039556 protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" 0005634=nucleus CG12260 "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG33213 16-Dec-15 2015_12 DRSC14487 K 0.427836091 0.191772301 -0.016524796 -0.227774899 -0.410403374 -1.634802345 FBgn0065333 l(2)SH1869 lethal (2) SH1869 http://flybase.net/reports/FBgn0065333.html gene l(2)SH2 1869 16-Dec-15 2015_12 "lethal,recessive" FBgn0039117 tst twister http://flybase.net/reports/FBgn0039117.html protein_coding_gene "0005524=ATP binding, 0003724=RNA helicase activity, 0004386=helicase activity, 0003723=RNA binding" "0006401=RNA catabolic process, 0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "Ski2/tst, Ski2, SKI2, CG10210, cg10210, Twister" "IPR025696=rRNA-processing arch domain, IPR012961=ATP-dependent RNA helicase Ski2, C-terminal, IPR001650=Helicase, C-terminal, IPR016438=ATP-dependent RNA helicase Ski2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain" CG10210 16-Dec-15 2015_12 ENSDARG00000062206(skiv2l) YLR398C(SKI2) WBGene00008502(F01G4.3) ENSXETG00000010932(SKIV2L) ENSMUSG00000040356(Skiv2l) "ENSG00000206353,ENSG00000206267,ENSG00000204351(SKIV2L)" viable DRSC14212 E -0.190674354 -0.480329478 -2.946387522 -0.333193317 -0.361715794 1.077340184 FBgn0084911 W143 W143 http://flybase.net/reports/FBgn0084911.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0264607 CaMKII Calcium/calmodulin-dependent protein kinase II http://flybase.net/reports/FBgn0264607.html "FBgn0004624, FBgn0004537" protein_coding_gene "0005516=calmodulin binding, 0004674=protein serine/threonine kinase activity, 0004683=calmodulin-dependent protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0007619=courtship behavior, 0007616=long-term memory, 0051489=regulation of filopodium assembly, 0007268=synaptic transmission, 0007528=neuromuscular junction development, 0007611=learning or memory, 0008582=regulation of synaptic growth at neuromuscular junction, 0008049=male courtship behavior, 0060278=regulation of ovulation" "0048786=presynaptic active zone, 0005886=plasma membrane, 0030425=dendrite, 0030424=axon, 0005737=cytoplasm, 0005954=calcium- and calmodulin-dependent protein kinase complex, 0045211=postsynaptic membrane" "CaM kinase, CAMKIIalpha, Ca2+ calmodulin-dependent kinase II, calmodulin-dependent protein kinase II, dCaMKII, Ca[2+]/Calmodulin-dependent protein kinase II, CAMKIId, Calmodulin kinase II, CaM-kinase-II, CaMK-II, CaM II, calmodulin-dependent kinase, lethal (4) 102EFb, Camkii, l(4)ar, Ca2+/calmodulin-dependent protein kinase II, CamKIIalpha, dCAMKII, calcium/ calmodulin-dependent protein kinase II, Ca[2+]/calmodulin-dependent protein kinase II, calcium/calmodulin-dependent protein kinase II, CaM kinase II, CAMKII, CaMK II, l(4)102EFb, l(4)16, Cam, camKII, DCK, CaM KII, CamKII, CG18069, CaM, Calcium/calmodulin-dependent protein kinase, CDPK1" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR013543=Calcium/calmodulin-dependent protein kinase II, association-domain, IPR020636=Calcium/calmodulin-dependent/calcium-dependent protein kinase, IPR008271=Serine/threonine-protein kinase, active site" CG18069 16-Dec-15 2015_12 "ENSDARG00000011065(zgc:165373),ENSDARG00000014273(camk2d2),ENSDARG00000071395(camk2g1),ENSDARG00000053617(camk2a),ENSDARG00000021065(LOC798222),ENSDARG00000056206(camk2g2)" "ENSXETG00000018971(CAMK2B),ENSXETG00000006455(CAMK2G)" "ENSMUSG00000057897(Camk2b),ENSMUSG00000053819(Camk2d),ENSMUSG00000021820(Camk2g),ENSMUSG00000024617(Camk2a)" "ENSG00000145349(CAMK2D),ENSG00000058404(CAMK2B),ENSG00000070808(CAMK2A),ENSG00000148660(CAMK2G)" adult stage adult head

FBgn0051944 tRNA:CR31944 transfer RNA:CR31944 http://flybase.net/reports/FBgn0051944.html FBgn0060104 tRNA_gene 0033428=CAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002638.trna10-GlnCTG, tRNA:Q:CTG:AE002638-e, chr2L.trna3-GlnCTG, CR31944" CR31944 16-Dec-15 2015_12 FBgn0263033 CG43328 http://flybase.net/reports/FBgn0263033.html "FBan0030459, FBgn0050459" protein_coding_gene CG30459 CG43328 16-Dec-15 2015_12 FBgn0001282 je jelly http://flybase.net/reports/FBgn0001282.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0002581 M(1)4BC Minute (1) 4BC http://flybase.net/reports/FBgn0002581.html gene M(1)4B/C 16-Dec-15 2015_12 FBgn0031731 CG14007 http://flybase.net/reports/FBgn0031731.html protein_coding_gene CG14007 16-Dec-15 2015_12 "viable,fertile" FBgn0036556 CG5830 http://flybase.net/reports/FBgn0036556.html protein_coding_gene 0008420=CTD phosphatase activity 0006470=protein dephosphorylation 0005886=plasma membrane 24664944 "IPR023214=HAD-like domain, IPR004274=FCP1 homology domain, IPR011948=Dullard phosphatase domain, eukaryotic" CG5830 16-Dec-15 2015_12 "ENSDARG00000062116(ctdsplb),ENSDARG00000071673(ctdspla),ENSDARG00000040674(zgc:113169)" "YLR019W(PSR2),YLL010C(PSR1)" "ENSXETG00000018471(CTDSPL),ENSXETG00000014963(CTDSP1)" "ENSMUSG00000026176(Ctdsp1),ENSMUSG00000047409(Ctdspl)" "ENSG00000144579(CTDSP1),ENSG00000144677(CTDSPL)" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014206 l(1)17Aa lethal (1) 17Aa http://flybase.net/reports/FBgn0014206.html gene 9130 16-Dec-15 2015_12 "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0084014 CG41451 http://flybase.net/reports/FBgn0084014.html FBan0041451 protein_coding_gene 16-Dec-15 2015_12 FBgn0034959 CG11388 http://flybase.net/reports/FBgn0034959.html FBgn0027694 protein_coding_gene "anon-EST:Posey287, dibeta3GnT6" IPR029044=Nucleotide-diphospho-sugar transferases CG11388 16-Dec-15 2015_12 ENSDARG00000070417(LOC565851) ENSXETG00000003454(C3orf21) ENSMUSG00000047434(AI480653) ENSG00000173950(C3orf21) "viable,fertile" FBgn0028744 CG5033 http://flybase.net/reports/FBgn0028744.html protein_coding_gene 0043021=ribonucleoprotein complex binding "0035206=regulation of hemocyte proliferation, 0006364=rRNA processing, 0022008=neurogenesis, 0040018=positive regulation of multicellular organism growth, 0042254=ribosome biogenesis" 0005730=nucleolus "EG:52C10.1, dWDR36" "IPR001680=WD40 repeat, IPR028598=WD repeat BOP1/Erb1, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR012953=BOP1, N-terminal domain" CG5033 16-Dec-15 2015_12 ENSDARG00000063627(bop1) YMR049C(ERB1) WBGene00012978(Y48B6A.1) ENSMUSG00000022557(Bop1) "ENSG00000170727(BOP1),ENSG00000204775" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0023165 Su(mg)1-2 Suppressor of modifier of gypsy 1-2 http://flybase.net/reports/FBgn0023165.html gene 16-Dec-15 2015_12 FBgn0060923 l(3)S042238b lethal (3) S042238b http://flybase.net/reports/FBgn0060923.html gene 0422/38 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0002693 mch minute chaetae http://flybase.net/reports/FBgn0002693.html gene 16-Dec-15 2015_12 "visible,viable,male,male fertile" "macrochaeta,microchaeta" FBgn0050414 CG30414 http://flybase.net/reports/FBgn0050414.html FBgn0034857 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "FBgn0050414, CG3487, SP62" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG30414 16-Dec-15 2015_12 ENSDARG00000051929 WBGene00006621(try-3) "viable,fertile" FBgn0014265 oho48A overgrown hematopoietic organs 48A http://flybase.net/reports/FBgn0014265.html gene 0048542=lymph gland development "l(2)65/24, l(2)k06524" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0000950 Fs(2)Bar Female sterile (2) Barsa http://flybase.net/reports/FBgn0000950.html gene "Barsa, Fs(2)Sz1" 16-Dec-15 2015_12 "female sterile,dominant,female sterile germline-dependent" "dorsal appendage,egg,cephalopharyngeal skeleton" FBgn0030542 CG12481 http://flybase.net/reports/FBgn0030542.html protein_coding_gene CG12481 16-Dec-15 2015_12 FBgn0053449 5SrRNA:CR33449 5SrRNA:CR33449 http://flybase.net/reports/FBgn0053449.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33449 CR33449 16-Dec-15 2015_12 FBgn0262078 JC01 http://flybase.net/reports/FBgn0262078.html gene 0072347=response to anesthetic 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0039323 CG10559 http://flybase.net/reports/FBgn0039323.html protein_coding_gene "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG10559 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0262341 mir-976 mir-976 stem loop http://flybase.net/reports/FBgn0262341.html miRNA_gene "dme-mir-976, 976, miR-976, CR43048, miR976" CR43048 16-Dec-15 2015_12 "visible,viable,lethal" "wing,wing vein L5" FBgn0039440 TwdlJ TweedleJ http://flybase.net/reports/FBgn0039440.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" "0005576=extracellular region, 0005578=proteinaceous extracellular matrix" CG5471 IPR004145=Domain of unknown function DUF243 CG5471 16-Dec-15 2015_12 FBgn0004437 pmst pmst http://flybase.net/reports/FBgn0004437.html gene PMST 16-Dec-15 2015_12 FBgn0082627 S(CycEJP)3.1 S(CycEJP)3.1 http://flybase.net/reports/FBgn0082627.html gene Complementation group 3.1 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0263597 Acp98AB Accessory gland protein 98AB http://flybase.net/reports/FBgn0263597.html "FBgn0013745, FBgn0051056" protein_coding_gene 0005179=hormone activity "0045434=negative regulation of female receptivity, post-mating, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "Acp98Ab, CG43619, Accessory gland-specific peptide 98B, Accessory gland protein 98AB, Accessory gland-specific peptide 98AB, CG31056, Acp98B, Acp98" CG43619 16-Dec-15 2015_12 adult stage | male " male accessory gland

, male accessory gland main cell

" DRSC21837 E 0.625820062 -0.260901548 1.873042063 1.67255163 -0.175123677 0.718638171 FBgn0001769 l(1)M39 lethal (1) M39 http://flybase.net/reports/FBgn0001769.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0016627 E(gl)2C Enhancer of glass 2C http://flybase.net/reports/FBgn0016627.html gene 16-Dec-15 2015_12 "lethal,recessive" rhabdomere FBgn0037124 CG14568 http://flybase.net/reports/FBgn0037124.html FBgn0047149 protein_coding_gene BcDNA:RE21944 CG14568 16-Dec-15 2015_12 viable FBgn0085296 CG34267 http://flybase.net/reports/FBgn0085296.html protein_coding_gene CG34267 16-Dec-15 2015_12 FBgn0265481 BG01744 http://flybase.net/reports/FBgn0265481.html gene 16-Dec-15 2015_12 sleep defective FBgn0010761 l(3)01728 lethal (3) 01728 http://flybase.net/reports/FBgn0010761.html gene 16-Dec-15 2015_12 "lethal,recessive" "esophageal ganglion 1,esophageal ganglion 2,stomodeal nerve" FBgn0259993 CR42491 http://flybase.net/reports/FBgn0259993.html non_protein_coding_gene CR42491 16-Dec-15 2015_12 FBgn0004971 l(1)4Fa lethal (1) 4Fa http://flybase.net/reports/FBgn0004971.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000362 cpl cupola http://flybase.net/reports/FBgn0000362.html gene 16-Dec-15 2015_12 "visible,male sterile,recessive" "adult head,eye,wing,tergite,abdominal tergite 6,abdominal tergite 7" FBgn0267959 CR46239 http://flybase.net/reports/FBgn0267959.html non_protein_coding_gene lincRNA.772 CR46239 16-Dec-15 2015_12 FBgn0005079 fs(2)OW803 female sterile (2) OW803 http://flybase.net/reports/FBgn0005079.html gene 16-Dec-15 2015_12 FBgn0005740 l(1)TK232 lethal (1) TK232 http://flybase.net/reports/FBgn0005740.html gene l232 16-Dec-15 2015_12 "lethal,recessive" FBgn0000678 flrdA flight reduced A http://flybase.net/reports/FBgn0000678.html gene 0007629=flight behavior 16-Dec-15 2015_12 flight defective FBgn0063667 CG32335 http://flybase.net/reports/FBgn0063667.html FBgn0052335 protein_coding_gene "0016788=hydrolase activity, acting on ester bonds, 0008270=zinc ion binding" 0005634=nucleus BcDNA:RE72485 IPR015021=Domain of unknown function DUF1907 CG32335 16-Dec-15 2015_12 ENSDARG00000016655(zgc:85789) WBGene00016046(C24B5.4) ENSXETG00000018450(TEgg069a24.1) ENSMUSG00000031938(4931406C07Rik) ENSG00000182919(C11orf54) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0024514 l(3)06886 lethal (3) 06886 http://flybase.net/reports/FBgn0024514.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038006 Cyp313a2 Cyp313a2 http://flybase.net/reports/FBgn0038006.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "Cyp313A2, CG10094, CYP313A2, 313a2" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG10094 16-Dec-15 2015_12 YDR402C(DIT2) "viable,fertile" FBgn0283461 Drs Drosomycin http://flybase.net/reports/FBgn0283461.html "FBgn0010381, FBgn0063123, FBgn0067901" protein_coding_gene "0006952=defense response, 0019732=antifungal humoral response, 0009617=response to bacterium, 0051715=cytolysis in other organism, 0050829=defense response to Gram-negative bacterium, 0042832=defense response to protozoan, 0050832=defense response to fungus, 0045087=innate immune response, 0019731=antibacterial humoral response" 0005576=extracellular region "DROM, BcDNA:LP03851, DIM 19, DIM 21, cysteine-rich peptide, DROS, drom, Immune induced molecule 21, Crp, drm, Cysteine-rich-protein, drosomycin, DRO, DRS, drosomyci, dmy1, Drosomycin precursor, Drm, Drosomycine, Drosomcycin, drsm, Dros, IM21, Drosomysin, CG10810, Drosomycin-B, drs, Drosophila Immune induced molecule 19, Drosomyocin, Drom, drosomyocin, Droso" "IPR003614=Knottin, scorpion toxin-like" CG10810 16-Dec-15 2015_12 "viable,immune response defective" FBgn0267554 CR45894 http://flybase.net/reports/FBgn0267554.html non_protein_coding_gene CR45894 16-Dec-15 2015_12 FBgn0031781 Arpc4 "Actin-related protein 2/3 complex, subunit 4" http://flybase.net/reports/FBgn0031781.html "FBgn0025530, FBgn0063015" protein_coding_gene "0005200=structural constituent of cytoskeleton, 0003779=actin binding" "0008360=regulation of cell shape, 0006909=phagocytosis, 0030866=cortical actin cytoskeleton organization, 0000902=cell morphogenesis, 0033627=cell adhesion mediated by integrin, 0030031=cell projection assembly, 0042060=wound healing, 0034314=Arp2/3 complex-mediated actin nucleation" 0005885=Arp2/3 protein complex "Arpc4, arc-p20, Arp-p20, CG5972, p20, p20 subunit of Arp2/3, p20 of Arp2/3 complex, Arc-p20, Arp2/3 subunit p20, P-20 ARC, BcDNA:RE43724, Arp2/3 Complex (p20 subunit), anon-EST:Posey49, p20Arc, ARPC4" IPR008384=Actin-related protein 2/3 complex subunit 4 CG5972 16-Dec-15 2015_12 "ENSDARG00000058225(arpc4l),ENSDARG00000054063(arpc4)" YKL013C(ARC19) WBGene00000204(arx-6) ENSXETG00000023675(arpc4) ENSMUSG00000079426(Arpc4) "lethal,recessive,cell shape defective,visible" wing DRSC02917 I 0.50256771 -1.796476883 -0.740272763 -0.927775043 -0.270433441 -0.741720588 FBgn0016696 Pitslre Pitslre http://flybase.net/reports/FBgn0016696.html FBgn0013968 protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004693=cyclin-dependent protein serine/threonine kinase activity, 0005524=ATP binding" "0008360=regulation of cell shape, 0006468=protein phosphorylation, 0007155=cell adhesion, 0000278=mitotic cell cycle, 0051726=regulation of cell cycle" 0005634=nucleus "Gat, pitslre, PITSLRE, PitsIre, Gat-like, Galactosyltransferase-associated kinase-like, CG4268, cdk11, group 3, PITSLRE kinase, Gta" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain" CG4268 16-Dec-15 2015_12 "WBGene00015203(B0495.2),WBGene00013917(ZC504.3)" ENSXETG00000019606(TNeu071o08.1) ENSMUSG00000029062(Cdk11b) "ENSG00000008128(CDK11A),ENSG00000189229" " embryonic stage | late , embryonic stage | early , embryonic stage&&pupal stage&&adult stage " " embryonic nervous system

,

ubiquitous , embryonic central nervous system

" DRSC11874 EK 0.040949138 1.277209906 1.576646369 -1.301116576 -1.638855036 -0.975743589 FBgn0062579 Mod(var)600 Mod(var)600 http://flybase.net/reports/FBgn0062579.html gene 0006342=chromatin silencing 600 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0086405 BG01707 http://flybase.net/reports/FBgn0086405.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0264885 CR44076 http://flybase.net/reports/FBgn0264885.html non_protein_coding_gene CR44076 16-Dec-15 2015_12 FBgn0014883 Ssb-cF4 Single stranded-binding protein cF4 http://flybase.net/reports/FBgn0014883.html gene cF4 16-Dec-15 2015_12 FBgn0011128 l(1)Q202 lethal (1) Q202 http://flybase.net/reports/FBgn0011128.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0031250 Ent1 Equilibrative nucleoside transporter 1 http://flybase.net/reports/FBgn0031250.html FBgn0025211 protein_coding_gene 0005337=nucleoside transmembrane transporter activity 0015858=nucleoside transport 0016021=integral component of membrane "unnamed, anon-EST:fe2G2, anon-fast-evolving-2G2, ent1, DmEnt1, CG11907, dENT1, DmENT1" "IPR020846=Major facilitator superfamily domain, IPR002259=Equilibrative nucleoside transporter" CG11907 16-Dec-15 2015_12 "ENSDARG00000031651(zgc:113383),ENSDARG00000054447,ENSDARG00000001767(zgc:110527),ENSDARG00000033909(LOC100334018)" YAL022C(FUN26) ENSXETG00000020572(slc29a2) "ENSMUSG00000024891(Slc29a2),ENSMUSG00000023942(Slc29a1)" ENSG00000198246(SLC29A3) "lethal,visible,viable" "scutellar bristle,ectopic,wing,trichogen cell" FBgn0032156 CG13124 http://flybase.net/reports/FBgn0032156.html protein_coding_gene 0003723=RNA binding "IPR003890=MIF4G-like, type 3, IPR016024=Armadillo-type fold, IPR016021=MIF4G-like domain" CG13124 16-Dec-15 2015_12 WBGene00018405(F44A2.5) "viable,fertile" FBgn0053928 CG33928 http://flybase.net/reports/FBgn0053928.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33928 16-Dec-15 2015_12 FBgn0028161 l(3)S036912 lethal (3) S036912 http://flybase.net/reports/FBgn0028161.html gene 0369/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0052065 CG32065 http://flybase.net/reports/FBgn0052065.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060936 l(3)S041315b lethal (3) S041315b http://flybase.net/reports/FBgn0060936.html gene 0413/15 16-Dec-15 2015_12 lethal FBgn0000776 fs(1)A1268 female sterile (1) A1268 http://flybase.net/reports/FBgn0000776.html gene 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0034920 CG5597 http://flybase.net/reports/FBgn0034920.html protein_coding_gene "CT17698, 5597" "IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG5597 16-Dec-15 2015_12 viable DRSC04517 E 0.095482144 0.065224363 4.060675488 0.301437931 1.093982641 -0.4250697 FBgn0262867 Ptr Patched-related http://flybase.net/reports/FBgn0262867.html "FBgn0033068, FBgn0064144" protein_coding_gene "0008158=hedgehog receptor activity, 0004872=receptor activity" 0010004=gastrulation involving germ band extension "0016021=integral component of membrane, 0016324=apical plasma membrane, 0005886=plasma membrane, 0016328=lateral plasma membrane" "ptc-related gene, Ptr_Dm, ptr, Ptc-related, Ptc related, ptc-related-gene, CG11212, patched-related, Ptc-related Disp-like, Dmptr" "IPR003392=Patched, IPR000731=Sterol-sensing domain" CG11212 16-Dec-15 2015_12 "ENSDARG00000023809,ENSDARG00000068874(LOC100004901),ENSDARG00000010075,ENSDARG00000056212" "WBGene00004217(ptr-2),WBGene00004224(ptr-10)" ENSXETG00000004557(PTCHD3) ENSMUSG00000039198(Ptchd3) "ENSG00000165186(PTCHD1),ENSG00000178729" FBgn0017377 l(1)HM442 lethal (1) HM442 http://flybase.net/reports/FBgn0017377.html gene HM-442 16-Dec-15 2015_12 "lethal,recessive" FBgn0265193 Atf-2 Activating transcription factor-2 http://flybase.net/reports/FBgn0265193.html "FBgn0050420, FBgn0035072, FBtr0072381, FBpp0072288, FBtr0072382, FBpp0072289, FBgn0265181" protein_coding_gene "0043565=sequence-specific DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0042803=protein homodimerization activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0030431=sleep, 0010866=regulation of triglyceride biosynthetic process, 0034605=cellular response to heat, 0031453=positive regulation of heterochromatin assembly, 0070829=heterochromatin maintenance, 0002385=mucosal immune response, 0009651=response to salt stress, 0071470=cellular response to osmotic stress, 0051403=stress-activated MAPK cascade" "0031618=nuclear pericentric heterochromatin, 0005701=polytene chromosome chromocenter, 0005634=nucleus, 0005704=polytene chromosome band" "ATF2, atf-2, CG30420, CG44246, Atf2, DM5, dATF2, ATF-2, CG12850, dATF-2" IPR004827=Basic-leucine zipper domain CG44246 16-Dec-15 2015_12 "suppressor of variegation,maternal effect,heat stress response defective,locomotor behavior defective,immune response defective,stress response defective,small body,visible,osmotic stress response defective" "LNv neuron,embryonic/larval fat body,wing vein" FBgn0002000 l(2)36Ad lethal (2) 36Ad http://flybase.net/reports/FBgn0002000.html gene "l(2)HT-11, l(2L)HT-11" 16-Dec-15 2015_12 lethal FBgn0041107 ms(3)S125011b ms(3)S125011b http://flybase.net/reports/FBgn0041107.html gene "P2000, l(3)S125011, ms(3)S125011, 1250/11, l(3)125011, unnamed" 16-Dec-15 2015_12 "viable,male sterile,heat sensitive" FBgn0267608 CR45946 http://flybase.net/reports/FBgn0267608.html pseudogene_attribute CR45946 16-Dec-15 2015_12 FBgn0021826 l(2)k16105 lethal (2) k16105 http://flybase.net/reports/FBgn0021826.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0084110 nana nanahuatzin http://flybase.net/reports/FBgn0084110.html gene 16-Dec-15 2015_12 FBgn0082957 snoRNA:ë¬28S-3405d snoRNA:ë¬28S-3405d http://flybase.net/reports/FBgn0082957.html snoRNA_gene "psi28s-3405d, CR34623" CR34623 16-Dec-15 2015_12 FBgn0267380 T:E2f1.1-230 E2f1 degron sequence http://flybase.net/reports/FBgn0267380.html engineered_tag 16-Dec-15 2015_12 FBgn0035975 PGRP-LA Peptidoglycan recognition protein LA http://flybase.net/reports/FBgn0035975.html "FBgn0035974, FBgn0042200, FBgn0052042" protein_coding_gene "0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0008270=zinc ion binding" "0006952=defense response, 0009253=peptidoglycan catabolic process, 0009617=response to bacterium, 0006955=immune response, 0045087=innate immune response, 0016045=detection of bacterium" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "CG4384, PGRPLA, CG18614, CG4361, CG32042, pgrp-la" "IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein" CG32042 16-Dec-15 2015_12 "viable,fertile,partially lethal,partially lethal - majority die,some die during pupal stage" FBgn0260429 CG42524 http://flybase.net/reports/FBgn0260429.html protein_coding_gene CG42524 16-Dec-15 2015_12 FBgn0005159 l(2)G145 lethal (2) G145 http://flybase.net/reports/FBgn0005159.html gene 16-Dec-15 2015_12 lethal FBgn0263602 Tasp1 Taspase 1 http://flybase.net/reports/FBgn0263602.html "FBgn0036564, FBgn0062192, FBgn0005544" protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity, 0004067=asparaginase activity" "0016485=protein processing, 0050829=defense response to Gram-negative bacterium, 0007283=spermatogenesis" "CG5241, l(3)72Dl, anon-WO0118547.172, Taspase1, Drosophila Threonine Aspartase1, Taspase 1, dTasp, lethal (3) 72Dl, taspase 1" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000246=Peptidase T2, asparaginase 2" CG5241 16-Dec-15 2015_12 ENSDARG00000060580(tasp1) WBGene00010480(K01G5.9) ENSXETG00000008080(TASP1) ENSMUSG00000039033(Tasp1) ENSG00000089123(TASP1) FBgn0051694 CG31694 http://flybase.net/reports/FBgn0051694.html "FBgn0031475, FBgn0031477" protein_coding_gene 0046427=positive regulation of JAK-STAT cascade 0005829=cytosol "CG15401, CG3098" "IPR007701=Interferon-related developmental regulator, N-terminal, IPR016024=Armadillo-type fold, IPR006921=Interferon-related developmental regulator, C-terminal" CG31694 16-Dec-15 2015_12 "ENSDARG00000068708(ifrd1),ENSDARG00000036811(ifrd2)" WBGene00010232(F58B3.6) "ENSXETG00000009255(IFRD1),ENSXETG00000007325(IFRD2)" "ENSMUSG00000001627(Ifrd1),ENSMUSG00000010048(Ifrd2)" "ENSG00000214706(IFRD2),ENSG00000006652(IFRD1)" "viable,fertile" FBgn0037832 Desi Desiccate http://flybase.net/reports/FBgn0037832.html protein_coding_gene "0042169=SH2 domain binding, 0030165=PDZ domain binding" 0009269=response to desiccation 0016021=integral component of membrane CG14686 IPR006631=Protein of unknown function DM4/12 CG14686 16-Dec-15 2015_12 "stress response defective,viable,fertile" FBgn0031500 CG17221 http://flybase.net/reports/FBgn0031500.html protein_coding_gene "0008270=zinc ion binding, 0016491=oxidoreductase activity" "0016319=mushroom body development, 0055114=oxidation-reduction process" DM_7295851 "IPR002085=Alcohol dehydrogenase superfamily, zinc-type, IPR016040=NAD(P)-binding domain, IPR011032=GroES-like, IPR013154=Alcohol dehydrogenase, N-terminal" CG17221 16-Dec-15 2015_12 ENSDARG00000031366(rtn4ip1) "YMR152W(YIM1),YBL069W(AST1),YER101C(AST2)" WBGene00044305(F56H1.6) ENSXETG00000019269(RTN4IP1) ENSMUSG00000019864(Rtn4ip1) ENSG00000130347(RTN4IP1) "neuroanatomy defective,viable" adult mushroom body FBgn0005537 l(3)72De lethal (3) 72De http://flybase.net/reports/FBgn0005537.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 "lethal,visible,recessive" organism FBgn0265746 CR44553 http://flybase.net/reports/FBgn0265746.html non_protein_coding_gene CR44553 16-Dec-15 2015_12 FBgn0263495 CR43484 http://flybase.net/reports/FBgn0263495.html non_protein_coding_gene lincRNA.425 CR43484 16-Dec-15 2015_12 FBgn0002257 l(3)68Fb lethal (3) 68Fb http://flybase.net/reports/FBgn0002257.html gene "rsg19, rose-gespleten region interval 19, l(3)rsg19" 16-Dec-15 2015_12 lethal FBgn0264416 FCO-A http://flybase.net/reports/FBgn0264416.html gene 16-Dec-15 2015_12 egg chamber FBgn0024581 l(3)rN346 lethal (3) rN346 http://flybase.net/reports/FBgn0024581.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038769 CG10889 http://flybase.net/reports/FBgn0038769.html protein_coding_gene 0046872=metal ion binding "IPR021869=Ribonuclease Zc3h12a-like, NYN domain, IPR000571=Zinc finger, CCCH-type" CG10889 16-Dec-15 2015_12 "ENSDARG00000062463(LOC100002370),ENSDARG00000016062,ENSDARG00000005271(LOC798235)" WBGene00016260(C30F12.1) "ENSXETG00000011465(ZC3H12A),ENSXETG00000017794(ZC3H12B)" "ENSMUSG00000042677(Zc3h12a),ENSMUSG00000035045(Zc3h12b),ENSMUSG00000035164(Zc3h12c)" "ENSG00000149289(ZC3H12C),ENSG00000102053(ZC3H12B),ENSG00000163874(ZC3H12A)" viable FBgn0019741 l(1)9 lethal (1) 9 http://flybase.net/reports/FBgn0019741.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032971 ttm3 tiny tim 3 http://flybase.net/reports/FBgn0032971.html FBan0006691 protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0004722=protein serine/threonine phosphatase activity" "0007006=mitochondrial membrane organization, 0007005=mitochondrion organization, 0015031=protein transport, 0006470=protein dephosphorylation" "0005743=mitochondrial inner membrane, 0005739=mitochondrion, 0005744=mitochondrial inner membrane presequence translocase complex" CG6691 "IPR027111=Mitochondrial import inner membrane translocase subunit Tim50, IPR004274=FCP1 homology domain, IPR023214=HAD-like domain" CG6691 16-Dec-15 2015_12 ENSDARG00000031098(timm50) YPL063W(TIM50) WBGene00011897(scpl-4) ENSXETG00000002882(TIMM50) ENSMUSG00000003438(Timm50) ENSG00000105197(TIMM50) viable FBgn0020573 anon-59Fa anon-59Fa http://flybase.net/reports/FBgn0020573.html gene 12D3 16-Dec-15 2015_12 FBgn0002301 l(3)81Fb lethal (3) 81Fb http://flybase.net/reports/FBgn0002301.html gene "81Fb, l(3)Rh2" 16-Dec-15 2015_12 lethal FBgn0264285 Su(Mir)2C2-1 http://flybase.net/reports/FBgn0264285.html gene 16-Dec-15 2015_12 FBgn0034293 CG14495 http://flybase.net/reports/FBgn0034293.html protein_coding_gene IPR007931=Protein of unknown function DUF725 CG14495 16-Dec-15 2015_12 viable FBgn0260609 2L2615 http://flybase.net/reports/FBgn0260609.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0025933 hip11 hb-interacting protein 11 http://flybase.net/reports/FBgn0025933.html gene 16-Dec-15 2015_12 FBgn0011082 l(1)Q40 lethal (1) Q40 http://flybase.net/reports/FBgn0011082.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0036629 CG4573 http://flybase.net/reports/FBgn0036629.html protein_coding_gene "0005524=ATP binding, 0000049=tRNA binding, 0004818=glutamate-tRNA ligase activity" 0006424=glutamyl-tRNA aminoacylation 0005737=cytoplasm "IPR000924=Glutamyl/glutaminyl-tRNA synthetase, IPR020061=Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain, IPR020751=Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR008925=Aminoacyl-tRNA synthetase, class I, anticodon-binding, IPR020058=Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR004527=Glutamate-tRNA ligase, bacterial/mitochondrial" CG4573 16-Dec-15 2015_12 YOL033W(MSE1) WBGene00001338(ears-2) ENSXETG00000012433(BC080925.1) ENSMUSG00000030871(Ears2) ENSG00000103356(EARS2) "viable,visible" trichogen cell FBgn0053993 CG33993 http://flybase.net/reports/FBgn0053993.html "FBgn0035653, FBgn0035654, FBtr0077072, FBpp0076780, FBtr0077073, FBpp0076781" protein_coding_gene "CG13289, CG13290" IPR000980=SH2 domain CG33993 16-Dec-15 2015_12 "ENSDARG00000054340(sla1),ENSDARG00000020788(sla2)" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0032586 Tpr2 Tetratricopeptide repeat protein 2 http://flybase.net/reports/FBgn0032586.html FBgn0046263 protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding "dTPR2, dtpr2, tpr2, dtrpr2, CG4599, Tpr-2, Trp2, dTpr2, tetratricopeptide repeat protein 2, EU3220, BEST:LD24941, TPR2" "IPR013105=Tetratricopeptide repeat 2, IPR001440=Tetratricopeptide repeat 1, IPR001623=DnaJ domain, IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR018253=DnaJ domain, conserved site, IPR011990=Tetratricopeptide-like helical domain" CG4599 16-Dec-15 2015_12 ENSDARG00000058148(dnajc7) ENSXETG00000002295(dnajc7) ENSMUSG00000014195(Dnajc7) ENSG00000168259(DNAJC7) "visible,viable" "wing,eye" FBgn0031490 CG17264 http://flybase.net/reports/FBgn0031490.html protein_coding_gene IPR000859=CUB domain CG17264 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005210 l(3)LVMR lethal (3) LVMR http://flybase.net/reports/FBgn0005210.html gene 16-Dec-15 2015_12 lethal FBgn0029812 Prosë_2R1 Proteasome ë_2 subunit-related 1 http://flybase.net/reports/FBgn0029812.html protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0019774=proteasome core complex, beta-subunit complex" "CG18341, Proteasome beta2R1 subunit, beta2R1" "IPR023333=Proteasome B-type subunit, IPR024689=Proteasome beta subunit, C-terminal, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR001353=Proteasome, subunit alpha/beta, IPR000243=Peptidase T1A, proteasome beta-subunit, IPR016050=Proteasome beta-type subunit, conserved site" CG18341 16-Dec-15 2015_12 YOR157C(PUP1) WBGene00003948(pbs-2) FBgn0260379 GSd246 http://flybase.net/reports/FBgn0260379.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0267948 CR46228 http://flybase.net/reports/FBgn0267948.html non_protein_coding_gene lincRNA.729 CR46228 16-Dec-15 2015_12 FBgn0015219 Eig4F Ecdysone-induced gene 4F http://flybase.net/reports/FBgn0015219.html gene 4F 16-Dec-15 2015_12 FBgn0000885 fs(1)M83 female sterile (1) M83 http://flybase.net/reports/FBgn0000885.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0266945 CR45396 http://flybase.net/reports/FBgn0266945.html non_protein_coding_gene CR45396 16-Dec-15 2015_12 FBgn0262354 CG43052 http://flybase.net/reports/FBgn0262354.html protein_coding_gene MB6.chr2L.pasa.1468 CG43052 16-Dec-15 2015_12 FBgn0032036 CG13384 http://flybase.net/reports/FBgn0032036.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport "IPR013057=Amino acid transporter, transmembrane domain" CG13384 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "WBGene00012804(Y43F4B.7),WBGene00020837(T27A1.5)" "ENSXETG00000017123(SLC36A4),ENSXETG00000019424()" "ENSMUSG00000043885(Slc36a4),ENSMUSG00000020261(Slc36a1),ENSMUSG00000020264(Slc36a2),ENSMUSG00000049491(Slc36a3)" "ENSG00000123643(SLC36A1),ENSG00000186335(SLC36A2),ENSG00000186334(SLC36A3),ENSG00000180773(SLC36A4)" viable FBgn0032211 CG13138 http://flybase.net/reports/FBgn0032211.html protein_coding_gene CG13138 16-Dec-15 2015_12 viable FBgn0019785 l(1)20 lethal (1) 20 http://flybase.net/reports/FBgn0019785.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034884 CG17662 http://flybase.net/reports/FBgn0034884.html protein_coding_gene "0015267=channel activity, 0015250=water channel activity" 0055085=transmembrane transport 0016021=integral component of membrane Aqp17662 "IPR000425=Major intrinsic protein, IPR022357=Major intrinsic protein, conserved site, IPR023271=Aquaporin-like" CG17662 16-Dec-15 2015_12 YPR192W(AQY1) "WBGene00000172(aqp-4),WBGene00000174(aqp-6),WBGene00000173(aqp-5)" viable FBgn0082186 l(3)SzB67Aa lethal (3) SzB67Aa http://flybase.net/reports/FBgn0082186.html gene 16-Dec-15 2015_12 lethal FBgn0261718 DJ996 http://flybase.net/reports/FBgn0261718.html gene 16-Dec-15 2015_12 FBgn0024926 Su(var)3-c1101 Su(var)3-c1101 http://flybase.net/reports/FBgn0024926.html gene Su-var(3)c1101 16-Dec-15 2015_12 FBgn0034541 CG13437 http://flybase.net/reports/FBgn0034541.html protein_coding_gene CG13437 16-Dec-15 2015_12 viable FBgn0011562 ams adult male-specific transcript http://flybase.net/reports/FBgn0011562.html gene 16-Dec-15 2015_12 FBgn0085742 CR40546 http://flybase.net/reports/FBgn0085742.html FBan0040546 rRNA_gene CR40546 16-Dec-15 2015_12 FBgn0031174 CG1486 http://flybase.net/reports/FBgn0031174.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0016831=carboxy-lyase activity" 0019752=carboxylic acid metabolic process unnamed "IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase" CG1486 16-Dec-15 2015_12 ENSDARG00000007549(pdxdc1) WBGene00007593(C14H10.3) ENSXETG00000005533() ENSMUSG00000022680(Pdxdc1) "ENSG00000179889(PDXDC1),ENSG00000196696" FBgn0065555 l(2)SH1016 lethal (2) SH1016 http://flybase.net/reports/FBgn0065555.html gene l(2)SH2 1016 16-Dec-15 2015_12 "lethal,recessive" FBgn0053527 SIFa SIFamide http://flybase.net/reports/FBgn0053527.html "FBgn0035029, FBgn0064238" protein_coding_gene "0048018=receptor agonist activity, 0005179=hormone activity, 0005184=neuropeptide hormone activity, 0071855=neuropeptide receptor binding" "0007218=neuropeptide signaling pathway, 0048047=mating behavior, sex discrimination, 0007621=negative regulation of female receptivity" 0005615=extracellular space "CG33527, SIFR, IFAMIDE, Neb-LFamide, neuropeptide IFamide, neuropeptide AYRKPPFNGSIFamide, SIFa, SIFamide, AYRKPPFNGSLFamide, Drm-IFa, IFamide, IFa, Drm-SIFa" CG33527 16-Dec-15 2015_12 "courtship behavior defective,male,female" FBgn0025387 CG12184 http://flybase.net/reports/FBgn0025387.html protein_coding_gene "GH15731P, EG:66A1.3" IPR029299=ALMS motif CG12184 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0260998 AGAR-11 Autosomal general anesthetic resistant 11 http://flybase.net/reports/FBgn0260998.html gene autosomal general anesthetic resistant 11 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0058327 CG40327 http://flybase.net/reports/FBgn0058327.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028880 CG15256 http://flybase.net/reports/FBgn0028880.html FBgn0032566 protein_coding_gene BG:DS04862.2 CG15256 16-Dec-15 2015_12 "viable,fertile" FBgn0266392 CR45032 http://flybase.net/reports/FBgn0266392.html non_protein_coding_gene CR45032 16-Dec-15 2015_12 FBgn0000987 Fs(2)Kom Female sterile (2) Kompolt http://flybase.net/reports/FBgn0000987.html gene "Kompolt, Kom, Fs(2)Sz8" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant" embryo FBgn0266645 CR45152 http://flybase.net/reports/FBgn0266645.html non_protein_coding_gene CR45152 16-Dec-15 2015_12 FBgn0020342 anon-57Ca anon-57Ca http://flybase.net/reports/FBgn0020342.html gene 525 16-Dec-15 2015_12 FBgn0029037 l(2)J27 lethal (2) J27 http://flybase.net/reports/FBgn0029037.html gene J27 16-Dec-15 2015_12 "lethal,recessive" FBgn0067736 l(1)G0357 lethal (1) G0357 http://flybase.net/reports/FBgn0067736.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0010146 l(3)62g lethal (3) 62g http://flybase.net/reports/FBgn0010146.html gene 16-Dec-15 2015_12 FBgn0013462 fs(3)neo71 fs(3)neo71 http://flybase.net/reports/FBgn0013462.html gene unnamed 16-Dec-15 2015_12 "female sterile,lethal,maternal effect" FBgn0022121 l(2)k06612 lethal (2) k06612 http://flybase.net/reports/FBgn0022121.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267947 CR46227 http://flybase.net/reports/FBgn0267947.html non_protein_coding_gene lincRNA.654 CR46227 16-Dec-15 2015_12 FBgn0031471 CG3117 http://flybase.net/reports/FBgn0031471.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH94, c-SPH94" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG3117 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0036615 CG4933 http://flybase.net/reports/FBgn0036615.html protein_coding_gene 0004222=metalloendopeptidase activity 0022008=neurogenesis "IPR017860=Peptidase M22, conserved site, IPR000905=Gcp-like domain, IPR017861=Kae1/TsaD family" CG4933 16-Dec-15 2015_12 ENSDARG00000045846(osgep) YKR038C(KAE1) WBGene00022166(Y71H2AM.1) ENSXETG00000017006(OSGEP) ENSMUSG00000006289(Osgep) ENSG00000092094(OSGEP) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0259265 EP-457 http://flybase.net/reports/FBgn0259265.html gene 16-Dec-15 2015_12 visible wing FBgn0001751 l(1)HM24 lethal (1) HM24 http://flybase.net/reports/FBgn0001751.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0037067 Cpr78Ca Cuticular protein 78Ca http://flybase.net/reports/FBgn0037067.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG11310, DmelCpr78Ca" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG11310 16-Dec-15 2015_12 viable FBgn0065601 l(2)SH0866 lethal (2) SH0866 http://flybase.net/reports/FBgn0065601.html gene l(2)SH2 0866 16-Dec-15 2015_12 "lethal,recessive" FBgn0042151 CG18828 http://flybase.net/reports/FBgn0042151.html protein_coding_gene 16-Dec-15 2015_12 FBgn0037439 CG10286 http://flybase.net/reports/FBgn0037439.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG10286 16-Dec-15 2015_12 ENSDARG00000036076(heatr3) ENSXETG00000007091(BC088495.1) ENSMUSG00000031657(Heatr3) ENSG00000155393(HEATR3) "viable,fertile" FBgn0011521 l(3)rM731 lethal (3) rM731 http://flybase.net/reports/FBgn0011521.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069934 CG41117 http://flybase.net/reports/FBgn0069934.html FBan0041117 protein_coding_gene 16-Dec-15 2015_12 FBgn0002586 M(1)8F Minute (1) 8F http://flybase.net/reports/FBgn0002586.html gene "M(1)14-171, M(1)8E/F" 16-Dec-15 2015_12 "Minute,visible" macrochaeta FBgn0264900 CR44091 http://flybase.net/reports/FBgn0264900.html non_protein_coding_gene lincRNA.915 CR44091 16-Dec-15 2015_12 FBgn0262163 ë_NACtes5 http://flybase.net/reports/FBgn0262163.html pseudogene_attribute CR42877 CR42877 16-Dec-15 2015_12 FBgn0050064 CG30064 http://flybase.net/reports/FBgn0050064.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031397 CG15385 http://flybase.net/reports/FBgn0031397.html protein_coding_gene "0003993=acid phosphatase activity, 0052642=lysophosphatidic acid phosphatase activity" 0016311=dephosphorylation 0005737=cytoplasm "IPR000560=Histidine phosphatase superfamily, clade-2, IPR029033=Histidine phosphatase superfamily" CG15385 16-Dec-15 2015_12 ENSDARG00000040644(acpl2) ENSMUSG00000043587(Acpl2) ENSG00000155893(ACPL2) FBgn0044335 674 674 http://flybase.net/reports/FBgn0044335.html gene 0007436=larval salivary gland morphogenesis 16-Dec-15 2015_12 FBgn0031264 CG11835 http://flybase.net/reports/FBgn0031264.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006355=regulation of transcription, DNA-templated" 0005634=nucleus IPR002715=Nascent polypeptide-associated complex NAC domain CG11835 16-Dec-15 2015_12 DRSC00326 K 1.473266836 0.077467174 -0.407601442 -0.597030192 1.588041769 0.452451507 FBgn0262297 mir-2496 mir-2496 stem loop http://flybase.net/reports/FBgn0262297.html miRNA_gene "dme-mir-2496, CR43004" CR43004 16-Dec-15 2015_12 viable FBgn0266177 pre-mod(mdg4)-I http://flybase.net/reports/FBgn0266177.html protein_coding_gene CG44883 "IPR007588=Zinc finger, FLYWCH-type" CG44883 16-Dec-15 2015_12 FBgn0264980 CR44131 http://flybase.net/reports/FBgn0264980.html non_protein_coding_gene CR44131 16-Dec-15 2015_12 FBgn0052406 PVRAP PVR adaptor protein http://flybase.net/reports/FBgn0052406.html "FBgn0035659, FBgn0035660" protein_coding_gene 0005070=SH3/SH2 adaptor activity 0038202=TORC1 signaling "CG32406, CG6062, CG13292" IPR000980=SH2 domain CG32406 16-Dec-15 2015_12 "ENSDARG00000054340(sla1),ENSDARG00000020788(sla2)" "viable,fertile,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC10577 E 0.332946321 -0.130282994 1.665399125 0.195190791 -0.088462472 0.040212408 FBgn0261276 Opa1 Optic atrophy 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0261276.html "FBgn0033914, FBgn0010687, FBgn0086250, FBgn0084864" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0035073=pupariation, 0007005=mitochondrion organization, 0008053=mitochondrial fusion, 0010636=positive regulation of mitochondrial fusion, 0001745=compound eye morphogenesis, 0070584=mitochondrion morphogenesis" 0005739=mitochondrion "optic atrophy 1-like, opa1-like, OPA1-like, optic atrophy 1, opa1, dOpa1, Optic atrophy 1, CG8479, Drosophila optic atrophy 1-like, l(2)s3475, lethal (2) s3475, OPA1, Opa1-like, dOPA1, Opa1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001401=Dynamin, GTPase domain, IPR030381=Dynamin-type guanine nucleotide-binding (G) domain, IPR022812=Dynamin superfamily" CG8479 16-Dec-15 2015_12 "ENSDARG00000044329(opa1),ENSDARG00000070801(si:ch211-232m8.6)" WBGene00001134(eat-3) ENSXETG00000016841(OPA1) ENSMUSG00000038084(Opa1) ENSG00000198836(OPA1) FBgn0263890 D75 http://flybase.net/reports/FBgn0263890.html gene 16-Dec-15 2015_12 "cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0013581 l(3)82Fi lethal (3) 82Fi http://flybase.net/reports/FBgn0013581.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001953 l(2)28Ab lethal (2) 28Ab http://flybase.net/reports/FBgn0001953.html gene "K, Complementation group K" 16-Dec-15 2015_12 lethal FBgn0085513 CG40748 http://flybase.net/reports/FBgn0085513.html FBan0040748 protein_coding_gene 16-Dec-15 2015_12 FBgn0065369 l(2)SH1708 lethal (2) SH1708 http://flybase.net/reports/FBgn0065369.html gene l(2)SH2 1708 16-Dec-15 2015_12 "lethal,recessive" FBgn0030074 CG12662 http://flybase.net/reports/FBgn0030074.html protein_coding_gene IPR006617=Protein of unknown function DM8 CG12662 16-Dec-15 2015_12 viable FBgn0051570 tRNA:CR31570 transfer RNA:CR31570 http://flybase.net/reports/FBgn0051570.html "FBgn0004262, FBgn0060288" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033453=GCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "unnamed, CR31570, transfer RNA:?:90Ca, tRNA:-?:90Ca, tRNA:A:AGC:AE002708-a, chr3R.trna16-AlaAGC, tRNA[[Ala]], AE002708.trna10-AlaAGC" CR31570 16-Dec-15 2015_12 FBgn0038363 Acyp2 Acylphosphatase 2 http://flybase.net/reports/FBgn0038363.html protein_coding_gene "0003998=acylphosphatase activity, 0016787=hydrolase activity" 0044237=cellular metabolic process 0005737=cytoplasm "acylphosphatase, AcPDro2, CG18505" "IPR001792=Acylphosphatase-like domain, IPR020456=Acylphosphatase, IPR017968=Acylphosphatase, conserved site" CG18505 16-Dec-15 2015_12 ENSDARG00000060126(acyp1) ENSXETG00000013250(acyp1) ENSMUSG00000008822(Acyp1) viable FBgn0001484 l(1)10Ad lethal (1) 10Ad http://flybase.net/reports/FBgn0001484.html gene "l(1)dp05, Q66, l(1)BP8, l(1)dp024" 16-Dec-15 2015_12 "lethal,recessive,dominant,cold sensitive,female sterile,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,partially,rescuable maternal effect" "tergite,embryonic/first instar larval cuticle,germline clone,embryonic head" FBgn0054007 CG34007 http://flybase.net/reports/FBgn0054007.html FBgn0082886 protein_coding_gene "unnamed, BP1020" CG34007 16-Dec-15 2015_12 FBgn0022195 l(2)k04909b lethal (2) k04909b http://flybase.net/reports/FBgn0022195.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264411 FCE-D http://flybase.net/reports/FBgn0264411.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0050009 CR30009 http://flybase.net/reports/FBgn0050009.html FBgn0064892 non_protein_coding_gene "mRNA-like ncRNA in embryogenesis 31, BcDNA:RE30084, MRE31" CR30009 16-Dec-15 2015_12 FBgn0050456 CG30456 http://flybase.net/reports/FBgn0050456.html "FBgn0034192, FBgn0034193" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0007480=imaginal disc-derived leg morphogenesis, 0035025=positive regulation of Rho protein signal transduction" "CG15613, CG15612" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain" CG30456 16-Dec-15 2015_12 viable FBgn0024872 l(2)k05627 lethal (2) k05627 http://flybase.net/reports/FBgn0024872.html gene 16-Dec-15 2015_12 FBgn0264418 FCO-C http://flybase.net/reports/FBgn0264418.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0005550 l(3)85Ai lethal (3) 85Ai http://flybase.net/reports/FBgn0005550.html gene X 16-Dec-15 2015_12 FBgn0022666 Dep3 Dep3 http://flybase.net/reports/FBgn0022666.html gene 0003677=DNA binding 0005634=nucleus DEP3 16-Dec-15 2015_12 FBgn0013940 E(sina)46C Enhancer of seven in absentia at 46C http://flybase.net/reports/FBgn0013940.html gene 16-Dec-15 2015_12 "lethal,recessive" photoreceptor cell R7 FBgn0082978 snoRNA:ë¬28S-3091b snoRNA:ë¬28S-3091b http://flybase.net/reports/FBgn0082978.html snoRNA_gene "psi28s-3091b, CR34609" CR34609 16-Dec-15 2015_12 FBgn0264406 FCG-I http://flybase.net/reports/FBgn0264406.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0039861 pasha partner of drosha http://flybase.net/reports/FBgn0039861.html protein_coding_gene 0003725=double-stranded RNA binding "0007294=germarium-derived oocyte fate determination, 0007446=imaginal disc growth, 0016319=mushroom body development, 0031053=primary miRNA processing, 0030727=germarium-derived female germ-line cyst formation, 0035195=gene silencing by miRNA" 0005634=nucleus "CG1800, cg1800, DiGeorge critical region 8, dmDGCR8, DGCR8, pasha, Pasha, PASHA" IPR014720=Double-stranded RNA-binding domain CG1800 16-Dec-15 2015_12 ENSDARG00000035564(dgcr8) WBGene00011908(pash-1) ENSXETG00000006320(DGCR8) ENSMUSG00000022718(Dgcr8) ENSG00000128191(DGCR8) "lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during pupal stage,decreased cell number,neuroanatomy defective,visible,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,lethal,viable" "oocyte,germline clone,eye disc,central nervous system,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,mushroom body,gamma Kenyon cell,adult antennal lobe projection neuron DL1 adPN,somatic clone,eye,wing,chaeta & mesothoracic tergum | somatic clone,imaginal disc,embryonic/larval optic lobe,dendrite & ad PN | somatic clone,dendrite & lPN | somatic clone,dendrite & vPN | somatic clone,dendrite & DL1 adPN | somatic clone,dendrite & VA1d adPN | somatic clone,dendrite & DC3 adPN | somatic clone,dendrite & DA1 lPN | somatic clone,axon & DL1 adPN | somatic clone,trichogen cell,mesothoracic tergum" DRSC27821 K 0.491534514 0.130321684 -0.114528858 0.80390217 1.752152644 1.249595283 FBgn0001884 l(2)21Ba lethal (2) 21Ba http://flybase.net/reports/FBgn0001884.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011456 l(3)neo19 lethal (3) neo19 http://flybase.net/reports/FBgn0011456.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263967 CR43723 http://flybase.net/reports/FBgn0263967.html non_protein_coding_gene CR43723 16-Dec-15 2015_12 FBgn0069089 rng rung http://flybase.net/reports/FBgn0069089.html gene 16-Dec-15 2015_12 FBgn0267147 CR45587 http://flybase.net/reports/FBgn0267147.html non_protein_coding_gene CR45587 16-Dec-15 2015_12 FBgn0263209 CR43379 http://flybase.net/reports/FBgn0263209.html pseudogene_attribute CR43379 16-Dec-15 2015_12 FBgn0026431 Grip75 Grip75 http://flybase.net/reports/FBgn0026431.html FBgn0032257 protein_coding_gene "0005200=structural constituent of cytoskeleton, 0015631=tubulin binding" "0051297=centrosome organization, 0051298=centrosome duplication, 0007067=mitotic nuclear division, 0007058=spindle assembly involved in female meiosis II, 0007112=male meiosis cytokinesis, 0007020=microtubule nucleation, 0045450=bicoid mRNA localization, 0007052=mitotic spindle organization" "0005815=microtubule organizing center, 0008274=gamma-tubulin ring complex, 0000922=spindle pole" "Dgrip75s, DGrip75, 75p, Dgrip75/d75p, Dgrip75, d75p, CG6176" IPR007259=Gamma-tubulin complex component protein CG6176 16-Dec-15 2015_12 ENSDARG00000005374(tubgcp4) ENSXETG00000004708(TUBGCP4) ENSMUSG00000027263(Tubgcp4) ENSG00000137822(TUBGCP4) "viable,fertile,female sterile,meiotic cell cycle defective,female,male,mitotic cell cycle defective,maternal effect" "ovariole,germline clone,egg,Nebenkern,spermatid,spindle,macrochaeta,adult cuticle,condensed chromosome,embryonic/larval neuroblast,mitotic spindle | third instar larval stage,spindle | cleavage stage | maternal effect,S2 cell-line" DRSC03337 K 1.138431599 -0.354598737 0.789786941 -0.332056775 1.683736745 0.049176276 FBgn0039941 CG17167 http://flybase.net/reports/FBgn0039941.html "FBgn0058146, FBan0017167" protein_coding_gene "0008273=calcium, potassium:sodium antiporter activity" 0055085=transmembrane transport 0016021=integral component of membrane "CG40146, CG17167" "IPR004481=Sodium/potassium/calcium exchanger, IPR004837=Sodium/calcium exchanger membrane region" CG17167 16-Dec-15 2015_12 YDL206W() viable DRSC20903 I 1.70309004 -0.964260859 -0.374368677 -0.942154277 0.7301485 0.355667337 FBgn0263338 CR43419 http://flybase.net/reports/FBgn0263338.html non_protein_coding_gene CR43419 16-Dec-15 2015_12 FBgn0265557 12.167 http://flybase.net/reports/FBgn0265557.html gene 16-Dec-15 2015_12 learning defective FBgn0039217 CG13627 http://flybase.net/reports/FBgn0039217.html protein_coding_gene CG13627 16-Dec-15 2015_12 "viable,fertile" FBgn0030529 Clic Chloride intracellular channel http://flybase.net/reports/FBgn0030529.html FBgn0040150 protein_coding_gene "0005509=calcium ion binding, 0008289=lipid binding, 0005254=chloride channel activity" "0006821=chloride transport, 0006979=response to oxidative stress, 0048060=negative gravitaxis, 0097305=response to alcohol, 0008340=determination of adult lifespan" "0005654=nucleoplasm, 0005829=cytosol" "CG10997, l(1)G0472, DCLIC, DmCLIC, l(1)G0053, clic" "IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG10997 16-Dec-15 2015_12 "ENSDARG00000010625(clic2),ENSDARG00000025947(LOC100332405),ENSDARG00000022995(clic4),ENSDARG00000044776(clica),ENSDARG00000001009(LOC100333907),ENSDARG00000058858(clic1)" WBGene00001365(exc-4) "ENSXETG00000016268(clic5),ENSXETG00000003634(CLIC6),ENSXETG00000024073(clic1),ENSXETG00000001007(CLIC4),ENSXETG00000003974(Q6DJ51_XENTR)" "ENSMUSG00000023959(Clic5),ENSMUSG00000037242(Clic4),ENSMUSG00000007041(Clic1),ENSMUSG00000015093(Clic3)" "ENSG00000155962(CLIC2),ENSG00000169504(CLIC4),ENSG00000112782(CLIC5),ENSG00000096238,ENSG00000206394,ENSG00000213719(CLIC1),ENSG00000169583(CLIC3)" "lethal,heat sensitive,gravitaxis defective,viable,fertile,partially lethal - majority die,male,female,recessive,visible" trichogen cell FBgn0010441 pll pelle http://flybase.net/reports/FBgn0010441.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0019904=protein domain specific binding, 0005524=ATP binding, 0005515=protein binding" "0046777=protein autophosphorylation, 0006468=protein phosphorylation, 0019732=antifungal humoral response, 0007352=zygotic specification of dorsal/ventral axis, 0006952=defense response, 0009620=response to fungus, 0035172=hemocyte proliferation, 0030162=regulation of proteolysis, 0030097=hemopoiesis, 0048262=determination of dorsal/ventral asymmetry, 0006606=protein import into nucleus, 0007165=signal transduction, 0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway" "0005886=plasma membrane, 0005737=cytoplasm" "PELLE/IL-1, Pelle, PELLE, p11, Serine/threonine-protein kinase pelle, pll/IRAK1, CG5974" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR011029=Death-like domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000488=Death domain" CG5974 16-Dec-15 2015_12 "ENSDARG00000053131(LOC100330941),ENSDARG00000025949(irak1)" WBGene00004029(pik-1) ENSXETG00000014246(irak1) ENSMUSG00000059883(Irak4) "ENSG00000184216(IRAK1),ENSG00000134070(IRAK2)" " embryonic stage | early , larval stage && pupal stage , adult stage | female " "viable,fertile,lethal,maternal effect,cold sensitive,recessive,size defective,neuroanatomy defective,female sterile,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,heat sensitive" "embryonic ventral epidermis,embryonic/larval somatic muscle,macrochaeta,filzkorper,posterior spiracle primordium,medulla,lamina,axon & eye photoreceptor cell,hemocyte,embryonic/larval hemolymph,embryo,ventral" FBgn0260568 MENE(3R)-E http://flybase.net/reports/FBgn0260568.html gene MENE (3R)-E 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0065103 snmRNA:173 small non-messenger RNA 173 http://flybase.net/reports/FBgn0065103.html non_protein_coding_gene Dm-173 16-Dec-15 2015_12 FBgn0005551 l(3)85Aj lethal (3) 85Aj http://flybase.net/reports/FBgn0005551.html gene 16-Dec-15 2015_12 FBgn0046297 CR9284 http://flybase.net/reports/FBgn0046297.html "FBgn0040657, FBgn0044722" non_protein_coding_gene "BEST:GH11908, CG9284, bs30g10.y1, anon-WO0140519.157, Tes101" CR9284 16-Dec-15 2015_12 viable FBgn0002480 l(3)SG37 lethal (3) SG37 http://flybase.net/reports/FBgn0002480.html FBgn0004720 gene "l(3)B6, l(3)ds6" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0060507 l(3)S104509a lethal (3) S104509a http://flybase.net/reports/FBgn0060507.html gene 1045/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0025834 CG2879 http://flybase.net/reports/FBgn0025834.html protein_coding_gene EG:25E8.6 16-Dec-15 2015_12 FBgn0025515 fs(3)82EFa fs(3)82EFa http://flybase.net/reports/FBgn0025515.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0037060 CG10508 http://flybase.net/reports/FBgn0037060.html protein_coding_gene "IPR003892=Ubiquitin system component Cue, IPR001202=WW domain, IPR009060=UBA-like" CG10508 16-Dec-15 2015_12 "viable,fertile" FBgn0267696 CR46032 http://flybase.net/reports/FBgn0267696.html non_protein_coding_gene CR46032 16-Dec-15 2015_12 FBgn0037650 CG11977 http://flybase.net/reports/FBgn0037650.html protein_coding_gene 0032504=multicellular organism reproduction 0005576=extracellular region "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG11977 16-Dec-15 2015_12 viable FBgn0267815 CR46140 http://flybase.net/reports/FBgn0267815.html non_protein_coding_gene CR46140 16-Dec-15 2015_12 FBgn0037637 IscU IscU homolog http://flybase.net/reports/FBgn0037637.html protein_coding_gene "0051536=iron-sulfur cluster binding, 0005506=iron ion binding" 0016226=iron-sulfur cluster assembly "IscU homologue, CG9836, iscu, dIscU" "IPR011339=ISC system FeS cluster assembly, IscU scaffold, IPR002871=NIF system FeS cluster assembly, NifU, N-terminal" CG9836 16-Dec-15 2015_12 "ENSDARG00000067946,ENSDARG00000035596(si:ch211-191d15.2),ENSDARG00000026582(zgc:110331)" "YPL135W(ISU1),YOR226C(ISU2)" WBGene00012885(Y45F10D.4) ENSXETG00000027428(nifun) ENSMUSG00000025825(Iscu) ENSG00000136003(ISCU) "lethal - all die before end of pupal stage,some die during pupal stage,lethal,locomotor rhythm defective" DRSC16572 E -0.400850823 -0.577537775 -2.099001167 0.884902627 -0.385590337 1.367624983 FBgn0000197 Ble Bar-like eye http://flybase.net/reports/FBgn0000197.html gene 16-Dec-15 2015_12 "visible,dominant" eye FBgn0019760 l(1)74 lethal (1) 74 http://flybase.net/reports/FBgn0019760.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029865 CG15893 http://flybase.net/reports/FBgn0029865.html FBgn0042090 protein_coding_gene BEST:LD05774 16-Dec-15 2015_12 FBgn0267019 CR45463 http://flybase.net/reports/FBgn0267019.html non_protein_coding_gene CR45463 16-Dec-15 2015_12 FBgn0260997 CG42598 http://flybase.net/reports/FBgn0260997.html protein_coding_gene 0019028=viral capsid "IPR004302=Chitin-binding, domain 3" CG42598 16-Dec-15 2015_12 FBgn0053309 CG33309 http://flybase.net/reports/FBgn0053309.html "FBgn0028865, FBgn0045212" protein_coding_gene "NEST:bs22a11, DS06874.7, BG:DS06874.7" CG33309 16-Dec-15 2015_12 FBgn0050299 tRNA:CR30299 transfer RNA:CR30299 http://flybase.net/reports/FBgn0050299.html "FBgn0011988, FBgn0060043" tRNA_gene "0033437=ACU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:T3:47F, AE002787.trna27-ThrAGT, transfer RNA:thr3:47F, tRNA[Thr][[3]], CR30299, tRNA:thr3:47F, chr2R.trna86-ThrAGT, tRNA:T:AGT:AE002787-a, tRNA[[Thr]]" CR30299 16-Dec-15 2015_12 FBgn0037901 CG6744 http://flybase.net/reports/FBgn0037901.html protein_coding_gene "0008408=3'-5' exonuclease activity, 0003676=nucleic acid binding" 0016444=somatic cell DNA recombination "IPR002562=3'-5' exonuclease domain, IPR012337=Ribonuclease H-like domain" CG6744 16-Dec-15 2015_12 ENSDARG00000016117(zgc:175195) ENSXETG00000017930(c14orf114) ENSMUSG00000032705(Exd2) ENSG00000081177(EXD2) "viable,fertile" FBgn0015515 mpt-1 mpt-1 http://flybase.net/reports/FBgn0015515.html gene 16-Dec-15 2015_12 FBgn0036397 Nprl3 Nitrogen permease regulator-like 3 http://flybase.net/reports/FBgn0036397.html protein_coding_gene 0005515=protein binding "0007293=germarium-derived egg chamber formation, 0038202=TORC1 signaling, 0034198=cellular response to amino acid starvation, 0045792=negative regulation of cell size, 0048477=oogenesis" "0005737=cytoplasm, 0005634=nucleus, 0035859=Seh1-associated complex, 0044754=autolysosome" "CG8783, nprl3, NPR3" IPR005365=Nitrogen permease regulator 3 CG8783 16-Dec-15 2015_12 ENSDARG00000010918(si:ch211-5k11.11) WBGene00018072(F35H10.7) ENSXETG00000001136(C16orf35) ENSMUSG00000020289(Nprl3) ENSG00000103148(NPRL3) viable FBgn0016988 oho48E overgrown hematopoietic organs 48E http://flybase.net/reports/FBgn0016988.html gene "l(2)k13117, l(2)131/17" 16-Dec-15 2015_12 FBgn0051327 CG31327 http://flybase.net/reports/FBgn0051327.html FBgn0065005 protein_coding_gene BcDNA:AT17065 CG31327 16-Dec-15 2015_12 FBgn0267692 CR46028 http://flybase.net/reports/FBgn0267692.html non_protein_coding_gene CR46028 16-Dec-15 2015_12 FBgn0266644 CR45151 http://flybase.net/reports/FBgn0266644.html non_protein_coding_gene CR45151 16-Dec-15 2015_12 FBgn0033781 CG13319 http://flybase.net/reports/FBgn0033781.html FBgn0063236 protein_coding_gene 0000502=proteasome complex BcDNA:GH19585 CG13319 16-Dec-15 2015_12 "viable,fertile" FBgn0011293 a10 antennal protein 10 http://flybase.net/reports/FBgn0011293.html FBgn0010402 protein_coding_gene "0005550=pheromone binding, 0005549=odorant binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "Os-D, Phk-1, OS-D/A10, Pherokine 1, DmelCSP4, OS-D, CG6642, Pherokine1, A10" IPR005055=Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG6642 16-Dec-15 2015_12 adult stage " sacculus

, sensillum coeloconica of antennal segment 3

, antennal segment 3

" viable DRSC11319 E -0.041920829 -0.478821419 -1.706871378 -0.020651462 -0.406337912 0.270568887 FBgn0264428 CR43846 http://flybase.net/reports/FBgn0264428.html non_protein_coding_gene CR43846 16-Dec-15 2015_12 FBgn0085312 CG34283 http://flybase.net/reports/FBgn0085312.html protein_coding_gene "IPR022776=TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG34283 16-Dec-15 2015_12 ENSDARG00000000887(zgc:56699) WBGene00020286(T06A10.3) FBgn0032614 CG13284 http://flybase.net/reports/FBgn0032614.html protein_coding_gene 0016229=steroid dehydrogenase activity "0008285=negative regulation of cell proliferation, 0007030=Golgi organization, 0008152=metabolic process, 0006909=phagocytosis" 0005783=endoplasmic reticulum "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR" CG13284 16-Dec-15 2015_12 YBR159W(IFA38) ENSMUSG00000034189(Hsdl1) ENSG00000103160(HSDL1) FBgn0065376 l(2)SH1677 lethal (2) SH1677 http://flybase.net/reports/FBgn0065376.html gene l(2)SH2 1677 16-Dec-15 2015_12 "lethal,recessive" FBgn0030360 CG1806 http://flybase.net/reports/FBgn0030360.html protein_coding_gene "0005887=integral component of plasma membrane, 0016010=dystrophin-associated glycoprotein complex" IPR030429=Sarcospan CG1806 16-Dec-15 2015_12 viable FBgn0069172 mcl(3)Z0375 mcl(3)Z0375 http://flybase.net/reports/FBgn0069172.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0262425 mir-288 mir-288 stem loop http://flybase.net/reports/FBgn0262425.html "FBgn0067704, FBgn0262271" miRNA_gene "CR33604, miR-288, mir-288, Mir-288, CR42978" CR42978 16-Dec-15 2015_12 viable FBgn0065610 l(2)SH0838 lethal (2) SH0838 http://flybase.net/reports/FBgn0065610.html gene l(2)SH2 0838 16-Dec-15 2015_12 "lethal,recessive" FBgn0065095 snmRNA:400 small non-messenger RNA 400 http://flybase.net/reports/FBgn0065095.html FBgn0053699 non_protein_coding_gene "Dm-400, CR33699" CR33699 16-Dec-15 2015_12 FBgn0028910 tRNA:P:35Bc tRNA:P:35Bc http://flybase.net/reports/FBgn0028910.html "FBgn0051984, FBgn0060121" tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:P:AGG:AE002690-c, AE002690.trna12-ProAGG, CR31984, tRNA:pro, chr2L.trna21-ProAGG, BG:DS01486.4" CR31984 16-Dec-15 2015_12 FBgn0041250 Gr21a Gustatory receptor 21a http://flybase.net/reports/FBgn0041250.html FBgn0031278 protein_coding_gene 0008527=taste receptor activity "0010037=response to carbon dioxide, 0050909=sensory perception of taste, 0003031=detection of carbon dioxide" "0030425=dendrite, 0016021=integral component of membrane, 0043025=neuronal cell body" "GR21D1, CG13948, Gustatory receptor 21D.1, GR21a, Gr21D1, gr21a, 21D.1, (GR) 21a, GR21D.1, DmGr21a" IPR013604=7TM chemoreceptor CG13948 16-Dec-15 2015_12 DRSC00366 I 0.434181583 1.894095298 -0.087036894 0.457783959 -1.042821811 -0.207048129 FBgn0069996 BG01740 BG01740 http://flybase.net/reports/FBgn0069996.html gene 16-Dec-15 2015_12 stress response defective FBgn0027524 CG3909 http://flybase.net/reports/FBgn0027524.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity 0005634=nucleus "Ski8, BcDNA:LD21537, CG3039" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG3909 16-Dec-15 2015_12 ENSDARG00000007755(zgc:77675) ENSXETG00000009511(wdr61) ENSMUSG00000061559(Wdr61) ENSG00000140395(WDR61) viable "wing,posterior compartment" FBgn0085745 CR40565 http://flybase.net/reports/FBgn0085745.html FBan0040565 rRNA_gene CR40565 16-Dec-15 2015_12 FBgn0027102 su(N) su(N) http://flybase.net/reports/FBgn0027102.html gene "suppressor of confluens, su-co" 16-Dec-15 2015_12 FBgn0025143 ms(3)A4 ms(3)A4 http://flybase.net/reports/FBgn0025143.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0037304 CG1113 http://flybase.net/reports/FBgn0037304.html protein_coding_gene CG1113 16-Dec-15 2015_12 "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0266401 CR45041 http://flybase.net/reports/FBgn0266401.html non_protein_coding_gene CR45041 16-Dec-15 2015_12 FBgn0032068 LManV Lysosomal ë±-mannosidase V http://flybase.net/reports/FBgn0032068.html protein_coding_gene "0004559=alpha-mannosidase activity, 0030246=carbohydrate binding, 0008270=zinc ion binding" 0006013=mannose metabolic process 0005764=lysosome "CG9466, LManV" "IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR000602=Glycoside hydrolase family 38, N-terminal domain, IPR011013=Galactose mutarotase-like domain, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR015341=Glycoside hydrolase, family 38, central domain" CG9466 16-Dec-15 2015_12 WBGene00018877(aman-1) ENSXETG00000011609(MAN2B2) ENSMUSG00000005142(Man2b1) ENSG00000104774(MAN2B1) viable FBgn0024341 KH4-2 KH domain cDNA KH4-2 http://flybase.net/reports/FBgn0024341.html gene unnamed 16-Dec-15 2015_12 FBgn0067071 Mmap370 microtuble/microfilament-associated protein 370 http://flybase.net/reports/FBgn0067071.html gene MMAP370 16-Dec-15 2015_12 FBgn0051251 CG31251 http://flybase.net/reports/FBgn0051251.html FBgn0038537 protein_coding_gene "NudC-like, CG7477, NudC-L" "IPR025934=NudC N-terminal domain, IPR008978=HSP20-like chaperone, IPR027761=NudC domain-containing protein 3, IPR007052=CS domain" CG31251 16-Dec-15 2015_12 ENSDARG00000006005(nudcd3) ENSXETG00000018972(nudcd3) ENSMUSG00000053838(Nudcd3) ENSG00000015676(NUDCD3) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0259233 CG42331 http://flybase.net/reports/FBgn0259233.html "FBgn0039221, FBgn0039222" protein_coding_gene "0020037=heme binding, 0004601=peroxidase activity" "0055114=oxidation-reduction process, 0006979=response to oxidative stress" "CG13632, CG6879" "IPR019791=Haem peroxidase, animal, IPR010255=Haem peroxidase" CG42331 16-Dec-15 2015_12 """DRSC25930, DRSC16126"" " K 0.428453235 0.140144903 0.327253052 0.671705967 2.159999039 0.723259226 FBgn0019771 l(1)48 lethal (1) 48 http://flybase.net/reports/FBgn0019771.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034927 CG17656 http://flybase.net/reports/FBgn0034927.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000177 bh baldhead http://flybase.net/reports/FBgn0000177.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,female sterile" "ocellus,ocellar bristle,wing" FBgn0014307 l(3)neo58a lethal (3) neo58a http://flybase.net/reports/FBgn0014307.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001615 l(1)dd11 lethal (1) discs degenerate 11 http://flybase.net/reports/FBgn0001615.html gene "l(1)d deg11, l(1)d.deg.-11, l(1)d deg-11, l(1)d.deg.11, d.deg.-11" 16-Dec-15 2015_12 "cell lethal,germline clone,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0020514 A35 A35 http://flybase.net/reports/FBgn0020514.html gene unnamed 16-Dec-15 2015_12 FBgn0002874 mudl mudlike http://flybase.net/reports/FBgn0002874.html gene mud 16-Dec-15 2015_12 "visible,eye color defective" pigment cell FBgn0013775 DNA-ligII DNA ligase II http://flybase.net/reports/FBgn0013775.html FBgn0004596 gene 0003910=DNA ligase (ATP) activity 0005634=nucleus 16-Dec-15 2015_12 FBgn0029912 CG4557 http://flybase.net/reports/FBgn0029912.html protein_coding_gene 0017137=Rab GTPase binding 0005794=Golgi apparatus AAF46211 "IPR022092=TATA element modulatory factor 1 DNA binding, IPR022091=TATA element modulatory factor 1 TATA binding" CG4557 16-Dec-15 2015_12 ENSDARG00000057997(tmf1) ENSXETG00000016166(Q66IL1_XENTR) ENSMUSG00000030059(Tmf1) ENSG00000144747(TMF1) FBgn0000131 Ars-region9 Autonomous replicating sequence region 9 http://flybase.net/reports/FBgn0000131.html region "Ars sequence 9, Ars9, ars414" 16-Dec-15 2015_12 FBgn0052263 CG32263 http://flybase.net/reports/FBgn0052263.html FBgn0035463 protein_coding_gene 0016021=integral component of membrane CG10854 IPR007248=Mpv17/PMP22 CG32263 16-Dec-15 2015_12 YOR292C() ENSMUSG00000035559(Mpv17l2) ENSG00000127226 partially lethal - majority die FBgn0032399 CG6785 http://flybase.net/reports/FBgn0032399.html protein_coding_gene cg6785 CG6785 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259346 C56 http://flybase.net/reports/FBgn0259346.html gene 16-Dec-15 2015_12 "visible,lethal" "wing,chaeta" FBgn0069948 CG41075 http://flybase.net/reports/FBgn0069948.html FBan0041075 protein_coding_gene 16-Dec-15 2015_12 FBgn0065458 l(2)SH1384 lethal (2) SH1384 http://flybase.net/reports/FBgn0065458.html gene l(2)SH2 1384 16-Dec-15 2015_12 "lethal,recessive" FBgn0010149 l(3)DTS-I165 lethal (3) DTS-I165 http://flybase.net/reports/FBgn0010149.html gene DTS-I165 16-Dec-15 2015_12 "lethal,dominant,heat sensitive" FBgn0033208 mRpL52 mitochondrial ribosomal protein L52 http://flybase.net/reports/FBgn0033208.html FBgn0062972 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "MRP-L52, rpl52, rpl-52, BcDNA:RH01479, CG1577" CG1577 16-Dec-15 2015_12 ENSMUSG00000010406(Mrpl52) ENSG00000172590(MRPL52) "viable,visible" trichogen cell FBgn0030674 CG8184 http://flybase.net/reports/FBgn0030674.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0033227=dsRNA transport, 0016567=protein ubiquitination" "0005737=cytoplasm, 0005634=nucleus" URE-B1/CG8184 "IPR015940=Ubiquitin-associated domain, IPR010314=E3 ubiquitin ligase, domain of unknown function DUF913, IPR004170=WWE domain, IPR010309=E3 ubiquitin ligase, domain of unknown function DUF908, IPR016024=Armadillo-type fold, IPR025527=Domain of unknown function DUF4414, IPR009060=UBA-like, IPR000569=HECT domain" CG8184 16-Dec-15 2015_12 WBGene00022069(eel-1) ENSMUSG00000025261(Huwe1) ENSG00000086758(HUWE1) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0003554 Su(Cy) Suppressor of Curly http://flybase.net/reports/FBgn0003554.html gene 16-Dec-15 2015_12 FBgn0066362 jack jack http://flybase.net/reports/FBgn0066362.html gene "0048149=behavioral response to ethanol, 0007611=learning or memory, 0008355=olfactory learning" Jack 16-Dec-15 2015_12 "memory defective,chemical sensitive" FBgn0051080 TwdlH TweedleH http://flybase.net/reports/FBgn0051080.html FBgn0039442 protein_coding_gene 0008010=structural constituent of chitin-based larval cuticle 0040003=chitin-based cuticle development 0005578=proteinaceous extracellular matrix "CG31080, CG14241" IPR004145=Domain of unknown function DUF243 CG31080 16-Dec-15 2015_12 viable FBgn0061081 l(3)S013904 lethal (3) S013904 http://flybase.net/reports/FBgn0061081.html gene 0139/04 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0035714 CG8549 http://flybase.net/reports/FBgn0035714.html protein_coding_gene 0003723=RNA binding "0042273=ribosomal large subunit biogenesis, 0006364=rRNA processing" "0005634=nucleus, 0005737=cytoplasm" "IPR018978=Ribosome maturation protein SBDS, C-terminal, IPR019783=Ribosome maturation protein SBDS, N-terminal, IPR002140=Ribosome maturation protein SBDS, IPR018023=Ribosome maturation protein SBDS, conserved site" CG8549 16-Dec-15 2015_12 ENSDARG00000027803(sbds) YLR022C(SDO1) WBGene00021063(sbds-1) ENSXETG00000010093(sbds) ENSMUSG00000025337(Sbds) ENSG00000126524(SBDS) viable FBgn0264080 T:SS-boss Signal sequence of boss http://flybase.net/reports/FBgn0264080.html engineered_tag 16-Dec-15 2015_12 FBgn0037689 CG8135 http://flybase.net/reports/FBgn0037689.html protein_coding_gene IPR006876=LMBR1-like membrane protein CG8135 16-Dec-15 2015_12 "ENSDARG00000017312(lmbrd2b),ENSDARG00000034710(lmbrd2a)" WBGene00008165(C47G2.4) ENSXETG00000004796(LMBRD2) ENSMUSG00000039704(Lmbrd2) ENSG00000164187(LMBRD2) viable FBgn0085706 CG41580 http://flybase.net/reports/FBgn0085706.html FBan0041580 protein_coding_gene 16-Dec-15 2015_12 FBgn0052983 CG32983 http://flybase.net/reports/FBgn0052983.html FBgn0040960 protein_coding_gene CG18663 CG32983 16-Dec-15 2015_12 viable FBgn0015575 ë±-Est7 ë±-Esterase-7 http://flybase.net/reports/FBgn0015575.html "FBgn0004945, FBgn0020634, FBgn0020658" protein_coding_gene 0052689=carboxylic ester hydrolase activity "0019915=lipid storage, 0008340=determination of adult lifespan, 0046683=response to organophosphorus" "0005737=cytoplasm, 0005811=lipid particle" "CG1112, aE7, Malathion carboxylesterase, DmalphaE7, Est23, alpha-Esterase-7, carboxylesterase 23, alphaest-7, Aliesterase, Est-23, Mce, Ali, H, EST23, alphaE7, Esterase 23, unnamed, fragment H, Alpha-esterase-7, alpha-Est7, aliesteraseless, ali" "IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site, IPR029058=Alpha/Beta hydrolase fold" CG1112 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" "chemical resistant,chemical sensitive,short lived,viable,electrophoretic variant" FBgn0035955 CG5194 http://flybase.net/reports/FBgn0035955.html FBgn0044631 protein_coding_gene anon-WO0140519.239 CG5194 16-Dec-15 2015_12 FBgn0020284 l(3)08034 lethal (3) 08034 http://flybase.net/reports/FBgn0020284.html gene "unnamed, 8034" 16-Dec-15 2015_12 "lethal,recessive" FBgn0052141 CG32141 http://flybase.net/reports/FBgn0052141.html protein_coding_gene CG32141 16-Dec-15 2015_12 viable FBgn0028039 l(3)S100201 lethal (3) S100201 http://flybase.net/reports/FBgn0028039.html gene 1002/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0085653 CG41492 http://flybase.net/reports/FBgn0085653.html FBan0041492 protein_coding_gene 16-Dec-15 2015_12 FBgn0044426 M80-11 M80-11 http://flybase.net/reports/FBgn0044426.html gene 0001754=eye photoreceptor cell differentiation M80#11 16-Dec-15 2015_12 partially lethal - majority die FBgn0035691 CG7386 http://flybase.net/reports/FBgn0035691.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0022008=neurogenesis 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG7386 16-Dec-15 2015_12 WBGene00004773(sem-4) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0033312 CG8642 http://flybase.net/reports/FBgn0033312.html protein_coding_gene "Fibrinogen-related protein, AAF59068, FBpp0087808" "IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR020837=Fibrinogen, conserved site, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG8642 16-Dec-15 2015_12 "ENSDARG00000003025,ENSDARG00000012071(angptl1)" WBGene00020516(T15B7.1) "ENSXETG00000021893(ANGPTL4),ENSXETG00000010849(angptl3)" "ENSMUSG00000026841(Fibcd1),ENSMUSG00000026938(Fcna),ENSMUSG00000026835(Fcnb)" "ENSG00000160339(FCN2),ENSG00000142748(FCN3),ENSG00000085265(FCN1),ENSG00000166482(MFAP4)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0030487 CG12726 http://flybase.net/reports/FBgn0030487.html protein_coding_gene 16-Dec-15 2015_12 FBgn0014920 anon-72ABd anon-72ABd http://flybase.net/reports/FBgn0014920.html gene 16-Dec-15 2015_12 FBgn0029040 l(2)F32 lethal (2) F32 http://flybase.net/reports/FBgn0029040.html gene F32 16-Dec-15 2015_12 "lethal,recessive" FBgn0017394 l(1)10Bs lethal (1) 10Bs http://flybase.net/reports/FBgn0017394.html gene HM22 16-Dec-15 2015_12 "lethal,recessive" FBgn0001799 l(1)Mc1 lethal (1) Mc1 http://flybase.net/reports/FBgn0001799.html gene 16-Dec-15 2015_12 "visible,somatic clone,size defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,eye" FBgn0015982 l(2)PC4-H lethal (2) PC4-H http://flybase.net/reports/FBgn0015982.html gene l(2)PC4-K 16-Dec-15 2015_12 "lethal,recessive" FBgn0026217 l(3)06734 lethal (3) 06734 http://flybase.net/reports/FBgn0026217.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004222 l(3)84Fj lethal (3) 84Fj http://flybase.net/reports/FBgn0004222.html gene 16-Dec-15 2015_12 lethal FBgn0002969 nrs narrow scoop http://flybase.net/reports/FBgn0002969.html gene 16-Dec-15 2015_12 "visible,recessive,female semi-sterile,male fertile,viable,male,female fertile,reduced,eye color defective,body color defective" "wing,macrochaeta,eye,pigment cell" FBgn0023118 anon-10Ap anon-10Ap http://flybase.net/reports/FBgn0023118.html gene 8 16-Dec-15 2015_12 FBgn0015747 Lcp11 Larval cuticle protein 11 http://flybase.net/reports/FBgn0015747.html gene 0008010=structural constituent of chitin-based larval cuticle 16-Dec-15 2015_12 FBgn0026383 Ori93Fë_ Ori93Fë_ http://flybase.net/reports/FBgn0026383.html origin_of_replication oriDbeta 16-Dec-15 2015_12 FBgn0041131 l(2)45Ae lethal (2) 45Ae http://flybase.net/reports/FBgn0041131.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0028048 l(3)S096404 lethal (3) S096404 http://flybase.net/reports/FBgn0028048.html gene 0964/04 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0263942 BG00218 http://flybase.net/reports/FBgn0263942.html gene 16-Dec-15 2015_12 "long lived,female,male,heat stress response defective,starvation stress response defective,chemosensitive behavior defective" FBgn0262388 mir-92b mir-92b stem loop http://flybase.net/reports/FBgn0262388.html "FBgn0067681, FBgn0262209" miRNA_gene "0001745=compound eye morphogenesis, 0007526=larval somatic muscle development" "miR-92, dme-mir-92b, CR33572, miR-92B, mir-92b, CR42916, mIR-92b, miR-92b, dme-miR-92b" CR42916 16-Dec-15 2015_12 "lethal,visible,hypoactive,male" "wing,wing hair,wing sensillum,ectopic,embryonic/larval somatic muscle,A1-7 lateral transverse muscle,lateral transverse muscle,male" FBgn0259731 tal-2A http://flybase.net/reports/FBgn0259731.html protein_coding_gene "0007015=actin filament organization, 0002009=morphogenesis of an epithelium" "pri, tal, Pep2, CG42385, ORF 2A, ORF2, Dm2" CG42385 16-Dec-15 2015_12 FBgn0265000 CR44151 http://flybase.net/reports/FBgn0265000.html non_protein_coding_gene CR44151 16-Dec-15 2015_12 FBgn0086664 snoRNA:ë¬28S-2149 snoRNA:ë¬28S-2149 http://flybase.net/reports/FBgn0086664.html "FBgn0082992, FBgn0065078, FBgn0053776" snoRNA_gene 0005730=nucleolus "Dm-143, snoRNA:143, snoR143, Psi28S-2149, CR33776, psi28S-2149, Psi 28S-2149(SnoR143)" CR33776 16-Dec-15 2015_12 FBgn0020543 l(1)18DEb lethal (1) 18DEb http://flybase.net/reports/FBgn0020543.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0046712 GI GI http://flybase.net/reports/FBgn0046712.html gene 0004623=phospholipase A2 activity 0005576=extracellular region dGI 16-Dec-15 2015_12 FBgn0000791 fs(1)de1 female sterile (1) defective eggs 1 http://flybase.net/reports/FBgn0000791.html gene de1 16-Dec-15 2015_12 "female sterile,partially,recessive,female sterile germline-dependent" "dorsal appendage,endochorion,chorion" FBgn0031740 CG7239 http://flybase.net/reports/FBgn0031740.html FBgn0027711 protein_coding_gene anon-EST:Posey250 IPR026095=Myb/SANT-like DNA-binding domain-containing protein CG7239 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0041111 lilli lilliputian http://flybase.net/reports/FBgn0041111.html "FBgn0010466, FBgn0016741, FBgn0026635, FBgn0026643, FBgn0031481, FBgn0040119, FBgn0045826, FBgn0047289" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007379=segment specification, 0006355=regulation of transcription, DNA-templated, 0007365=periodic partitioning, 0000915=actomyosin contractile ring assembly, 0051493=regulation of cytoskeleton organization, 0032368=regulation of lipid transport, 0048190=wing disc dorsal/ventral pattern formation, 0042048=olfactory behavior, 0007366=periodic partitioning by pair rule gene, 0007611=learning or memory, 0042051=compound eye photoreceptor development, 0016049=cell growth, 0008283=cell proliferation, 0008361=regulation of cell size" "0005634=nucleus, 0032783=ELL-EAF complex" "BEST:GH09955, SY2-1, l(2)k16124, Suppressor of GMR-sina 2-1, S(ls)4, l(2)K07920, 189Y, Lilli, l(2)00632, l(2)23Cc, CG8817, Su(Raf)2a, BcDNA:GM02019, 154454_at, SS2-1, Su(Raf)2A, l(2)k07920, l(2)K00632, liliputian, AFF4, dAFF4" "IPR017956=AT hook, DNA-binding motif, IPR007797=Transcription factor AF4/FMR2" CG8817 16-Dec-15 2015_12 "ENSXETG00000019630(AFF2),ENSXETG00000004169(AFF4)" "ENSMUSG00000037138(Aff3),ENSMUSG00000031189(Aff2),ENSMUSG00000049470(Aff4),ENSMUSG00000029313(Aff1)" "ENSG00000155966(AFF2),ENSG00000144218(AFF3),ENSG00000072364(AFF4),ENSG00000172493(AFF1)" "lethal,recessive,viable,smell perception defective,fertile,maternal effect,poor,wild-type,decreased cell size,somatic clone,terminal phenotype,germline clone,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,pair rule phenotype,small body,memory defective,partially lethal - majority die" "embryonic/first instar larval cuticle,maternal effect,segment,eye photoreceptor cell,somatic clone,embryonic head,germline clone,embryonic segment,denticle belt,embryonic abdominal segment,cephalic furrow,extended germ band embryo,actin filament | embryonic stage | germline clone,yolk,lipid particle | germline clone,wing margin bristle,embryo,rhabdomere,cephalopharyngeal skeleton,anterior,filzkorper,embryonic epidermis,eye disc,eye,adult head,ommatidium" DRSC00708 IK 0.048651231 2.218757271 -0.296279498 -0.348312542 1.063191958 1.62912058 FBgn0262600 skf skiff http://flybase.net/reports/FBgn0262600.html gene 16-Dec-15 2015_12 FBgn0028531 CG15286 http://flybase.net/reports/FBgn0028531.html protein_coding_gene 0008270=zinc ion binding BG:DS01068.11 "IPR000433=Zinc finger, ZZ-type, IPR015880=Zinc finger, C2H2-like, IPR008598=Drought induced 19 protein type, zinc-binding domain" CG15286 16-Dec-15 2015_12 viable FBgn0033915 CG8485 http://flybase.net/reports/FBgn0033915.html protein_coding_gene "0005524=ATP binding, 0016909=SAP kinase activity, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation "152964_at, SNRK" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG8485 16-Dec-15 2015_12 ENSDARG00000070832 "YDR507C(GIN4),YCL024W(KCC4)" WBGene00013994(ZK524.4) ENSMUSG00000038145(Snrk) ENSG00000163788(SNRK) "partially lethal - majority die,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0011571 caz cabeza http://flybase.net/reports/FBgn0011571.html "FBgn0003059, FBgn0011830, FBgn0062479" protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding, 0008270=zinc ion binding" "0048749=compound eye development, 0006367=transcription initiation from RNA polymerase II promoter, 0008344=adult locomotory behavior, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0000398=mRNA splicing, via spliceosome, 0008345=larval locomotory behavior, 0051124=synaptic growth at neuromuscular junction" "0005634=nucleus, 0035327=transcriptionally active chromatin, 0005669=transcription factor TFIID complex, 0005654=nucleoplasm, 0071013=catalytic step 2 spliceosome" "P19, p19, CG3606, Sarfh, pen19, Caz, Cabeza, Pen19, BcDNA:GM09207, SARFH, EWSR1, cas, TFIID, Sarcoma-associated RNA-binding fly homolog, anon-Pen19, CABEZA" "IPR000504=RNA recognition motif domain, IPR001876=Zinc finger, RanBP2-type, IPR012677=Nucleotide-binding alpha-beta plait domain" CG3606 16-Dec-15 2015_12 "ENSDARG00000037968(fus),ENSDARG00000070019(zgc:158363),ENSDARG00000020258(ewsr1a),ENSDARG00000020465(ewsr1b)" WBGene00016173(C27H5.3) "ENSXETG00000001951(FUS),ENSXETG00000024796(EWSR1),ENSXETG00000013477(TAF15)" "ENSMUSG00000030795(Fus),ENSMUSG00000009079(Ewsr1),ENSMUSG00000020680(Taf15),ENSMUSG00000066554(Gm10167)" "ENSG00000089280(FUS),ENSG00000182944(EWSR1),ENSG00000172660(TAF15)" "wild-type,neuroanatomy defective,visible,locomotor behavior defective,progressive,gravitaxis defective,lethal,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,neurophysiology defective,viable,conditional,partially lethal - majority die" "embryonic/larval neuromuscular junction | third instar larval stage,eye,ommatidium,interommatidial bristle,embryonic/larval motor neuron | larval stage,NMJ bouton | larval stage,NMJ bouton | third instar larval stage,wing,conditional,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,ventral nerve cord | third instar larval stage,abdominal segment motor neuron | third instar larval stage,eye disc" FBgn0060772 l(3)S061318 lethal (3) S061318 http://flybase.net/reports/FBgn0060772.html gene 0613/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0265489 BG01420 http://flybase.net/reports/FBgn0265489.html gene 16-Dec-15 2015_12 FBgn0060716 l(3)S069617 lethal (3) S069617 http://flybase.net/reports/FBgn0060716.html gene 0696/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0040774 CG12922 http://flybase.net/reports/FBgn0040774.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001573 l(1)55a lethal (1) 55a http://flybase.net/reports/FBgn0001573.html gene l(1)55 16-Dec-15 2015_12 "lethal,heat sensitive" spermatogonium FBgn0031519 CG3326 http://flybase.net/reports/FBgn0031519.html protein_coding_gene "0016787=hydrolase activity, 0000287=magnesium ion binding, 0008568=microtubule-severing ATPase activity, 0005524=ATP binding" "0046034=ATP metabolic process, 0000070=mitotic sister chromatid segregation, 0051013=microtubule severing" "0005694=chromosome, 0005813=centrosome" "fidgetin_DROME, DmCG3326, Dm-fidgetin" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR015415=Vps4 oligomerisation, C-terminal, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG3326 16-Dec-15 2015_12 "ENSDARG00000016427(fignl1),ENSDARG00000008662" WBGene00017981(figl-1) "ENSXETG00000015704(FIGNL1),ENSXETG00000013165(FIGN)" "ENSMUSG00000035455(Fignl1),ENSMUSG00000075324(Fign)" "ENSG00000132436(FIGNL1),ENSG00000182263(FIGN)" viable FBgn0033327 PGRP-SC1b PGRP-SC1b http://flybase.net/reports/FBgn0033327.html protein_coding_gene "0008270=zinc ion binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0042834=peptidoglycan binding" "0016045=detection of bacterium, 0045087=innate immune response, 0006952=defense response, 0009253=peptidoglycan catabolic process" "0005887=integral component of plasma membrane, 0005576=extracellular region" "PGRP-SC1, CG8577, Peptidoglycan-recognition protein-SC1b precursor, CT8705, PGRP SC, PGRP-SC, SC1B, PGRP-SC1B" "IPR017331=Peptidoglycan recognition protein, PGRP-S, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510=Peptidoglycan recognition protein, IPR002502=N-acetylmuramoyl-L-alanine amidase domain" CG8577 16-Dec-15 2015_12 "ENSDARG00000023215,ENSDARG00000068382(pglyrp5)" "ENSXETG00000018262(BC089715.1),ENSXETG00000019028(BC091103.1)" ENSMUSG00000030413(Pglyrp1) ENSG00000008438(PGLYRP1) "viable,immune response defective" DRSC25294 K 1.912109246 -0.212964717 FBgn0053300 Muc30E Mucin 30E http://flybase.net/reports/FBgn0053300.html protein_coding_gene 0005201=extracellular matrix structural constituent 0031012=extracellular matrix "Muc30E, CG33300" CG33300 16-Dec-15 2015_12 viable FBgn0003112 plo pillow http://flybase.net/reports/FBgn0003112.html gene pil 16-Dec-15 2015_12 "visible,recessive" eye FBgn0035586 CG10671 http://flybase.net/reports/FBgn0035586.html protein_coding_gene 0019915=lipid storage 0005789=endoplasmic reticulum membrane "i136, FIT2" IPR019388=Fat storage-inducing transmembrane protein CG10671 16-Dec-15 2015_12 ENSDARG00000034568(fitm2) WBGene00044094(ZK265.9) ENSXETG00000001773(FITM2) ENSMUSG00000048486(Fitm2) ENSG00000197296(FITM2) viable FBgn0038124 CG14380 http://flybase.net/reports/FBgn0038124.html protein_coding_gene CG14380 16-Dec-15 2015_12 FBgn0265825 CR44614 http://flybase.net/reports/FBgn0265825.html non_protein_coding_gene CR44614 16-Dec-15 2015_12 FBgn0053289 ppk5 pickpocket 5 http://flybase.net/reports/FBgn0053289.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "unnamed, CG33289, pickpocket 5, ppk5" "IPR001873=Na+ channel, amiloride-sensitive" CG33289 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" WBGene00022815(asic-1) "ENSXETG00000022398(ACCN5),ENSXETG00000013366(ACCN3),ENSXETG00000014229(ACCN1)" "ENSMUSG00000020704(Accn1),ENSMUSG00000023017(Accn2),ENSMUSG00000038276(Accn3),ENSMUSG00000033007(Accn4),ENSMUSG00000028008(Accn5)" "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" "viable,touch sensitivity defective,lethal" DRSC11492 I 0.134597336 1.540437654 -0.094975625 0.021572925 0.392436073 0.372081595 FBgn0261537 CG42661 http://flybase.net/reports/FBgn0261537.html protein_coding_gene CG42661 16-Dec-15 2015_12 FBgn0032400 CG6770 http://flybase.net/reports/FBgn0032400.html FBgn0066037 protein_coding_gene 0006979=response to oxidative stress "p8, anon-WO02059370.25, CT21019" "IPR018792=Nuclear phosphoprotein p8, DNA binding" CG6770 16-Dec-15 2015_12 ENSDARG00000057453 ENSMUSG00000030717(Nupr1) "viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" DRSC02992 IEK -0.167034936 -5.187644813 -0.856982423 -6.256478003 -1.779807775 -1.148255143 FBgn0032454 CG5787 http://flybase.net/reports/FBgn0032454.html protein_coding_gene 0005875=microtubule associated complex IPR012981=PIH1 family CG5787 16-Dec-15 2015_12 "viable,fertile,visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0004807 fs(2)ltoAHE1 female sterile (2) ltoAHE1 http://flybase.net/reports/FBgn0004807.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0003976 vin vin http://flybase.net/reports/FBgn0003976.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive,eye color defective,lethal" pigment cell FBgn0037827 CG4073 http://flybase.net/reports/FBgn0037827.html protein_coding_gene CG4073 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0027527 Osi6 Osiris 6 http://flybase.net/reports/FBgn0027527.html protein_coding_gene "0012505=endomembrane system, 0005887=integral component of plasma membrane" "Osiris, BcDNA:LD21503, CG1151" IPR012464=Protein of unknown function DUF1676 CG1151 16-Dec-15 2015_12 lethal FBgn0037414 Osi7 Osiris 7 http://flybase.net/reports/FBgn0037414.html protein_coding_gene 0046331=lateral inhibition 0005887=integral component of plasma membrane "CG1153, Osiris, osi7" IPR012464=Protein of unknown function DUF1676 CG1153 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0266958 CR45409 http://flybase.net/reports/FBgn0266958.html non_protein_coding_gene CR45409 16-Dec-15 2015_12 FBgn0001440 l(1)7Cb lethal (1) 7Cb http://flybase.net/reports/FBgn0001440.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0038272 CG7265 http://flybase.net/reports/FBgn0038272.html protein_coding_gene 0017183=peptidyl-diphthamide biosynthetic process from peptidyl-histidine 0005737=cytoplasm "IPR016435=Diphthamide synthesis DPH1/DPH2, IPR010014=Diphthamide synthesis DHP2, eukaryotic" CG7265 16-Dec-15 2015_12 YKL191W(DPH2) WBGene00007488(dph-2) ENSXETG00000003493(DPH2) ENSMUSG00000028540(Dph2) ENSG00000132768(DPH2) viable FBgn0030034 CG10555 http://flybase.net/reports/FBgn0030034.html protein_coding_gene 0005515=protein binding "0045893=positive regulation of transcription, DNA-templated" 0005634=nucleus IPR007726=SS18 family CG10555 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0031093 CG9581 http://flybase.net/reports/FBgn0031093.html protein_coding_gene "0004177=aminopeptidase activity, 0030145=manganese ion binding" "IPR029149=Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980=Creatinase/Aminopeptidase P, N-terminal, IPR000994=Peptidase M24, structural domain, IPR001714=Peptidase M24, methionine aminopeptidase, IPR007865=Aminopeptidase P, N-terminal" CG9581 16-Dec-15 2015_12 ENSDARG00000007916(xpnpep3) YER078C(ICP55) WBGene00020088(R119.2) ENSXETG00000022973(TNeu078h21.1) ENSMUSG00000022401(Xpnpep3) ENSG00000196236(XPNPEP3) viable FBgn0262850 CR43214 http://flybase.net/reports/FBgn0262850.html pseudogene_attribute "noncoding_23159, noncoding_23161" CR43214 16-Dec-15 2015_12 FBgn0002094 l(2)57Bd lethal (2) 57Bd http://flybase.net/reports/FBgn0002094.html gene 16-Dec-15 2015_12 lethal FBgn0036373 Tgi Tondu-domain-containing Growth Inhibitor http://flybase.net/reports/FBgn0036373.html FBgn0045199 protein_coding_gene "0001223=transcription coactivator binding, 0008134=transcription factor binding" "0035331=negative regulation of hippo signaling, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "Tondu-domain-containing growth inhibitor, tgi, SdBP, CG10741, Sd-Binding-Protein, NEST:bs23g10" IPR006627=TDU repeat CG10741 16-Dec-15 2015_12 "visible,size defective,lethal - all die before end of second instar larval stage,majority die during second instar larval stage,viable,body color defective,fertile" "eye disc,somatic clone,wing disc,wing,wing | adult stage,mesothoracic tergum" FBgn0022813 E(faf)E263 Enhancer of faf E263 http://flybase.net/reports/FBgn0022813.html gene 16-Dec-15 2015_12 "viable,visible" FBgn0069398 LRP Low Density Lipoprotein http://flybase.net/reports/FBgn0069398.html gene 16-Dec-15 2015_12 FBgn0259610 B1500 http://flybase.net/reports/FBgn0259610.html gene 16-Dec-15 2015_12 visible wing FBgn0259729 CG42383 http://flybase.net/reports/FBgn0259729.html FBgn0027659 protein_coding_gene "CG4556, eyes closed, p47 NSFL1, eyc, p47" "IPR029071=Ubiquitin-related domain, IPR001012=UBX domain, IPR009060=UBA-like, IPR012989=SEP domain" CG42383 16-Dec-15 2015_12 YBL058W(SHP1) WBGene00022381(ubxn-2) ENSXETG00000018210(ubxd4) "visible,viable" "rhabdomere | heat sensitivehs.PB,endoplasmic reticulum | heat sensitivehs.PB,rhabdomereGMR.PF,mesothoracic tergum" FBgn0260718 CR42545 http://flybase.net/reports/FBgn0260718.html pseudogene_attribute CR42545 16-Dec-15 2015_12 FBgn0010039 GstD3 Glutathione S transferase D3 http://flybase.net/reports/FBgn0010039.html "FBgn0038022, FBgn0063086" protein_coding_gene 0004364=glutathione transferase activity 0005737=cytoplasm "GSTD3, gstd3, CG4381, GST-D3, DmGST22, Glutathione S transferase D22, GstD22, BcDNA:LP11313, gstD22, gstD3, Gst, D3, DmGSTD3" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG4381 16-Dec-15 2015_12 YNL229C(URE2) larval stage organism

"viable,body color defective" mesothoracic tergum FBgn0036529 pgant8 polypeptide GalNAc transferase 8 http://flybase.net/reports/FBgn0036529.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process 0005795=Golgi stack CG7297 "IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain, IPR001173=Glycosyltransferase 2-like, IPR027791=Galactosyltransferase, C-terminal" CG7297 16-Dec-15 2015_12 viable DRSC26909 K -0.326693474 0.222324759 -0.235142638 -0.163614424 2.697086751 0.395103467 FBgn0014348 ms(2)HB123 ms(2)HB123 http://flybase.net/reports/FBgn0014348.html gene 16-Dec-15 2015_12 FBgn0020915 Ost Ostrich http://flybase.net/reports/FBgn0020915.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces ost 16-Dec-15 2015_12 "visible,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage" wing FBgn0267036 CR45480 http://flybase.net/reports/FBgn0267036.html non_protein_coding_gene CR45480 16-Dec-15 2015_12 FBgn0045958 anon-AE003774.1 anon-AE003774.1 http://flybase.net/reports/FBgn0045958.html gene unnamed 16-Dec-15 2015_12 FBgn0003375 Sgs5 Salivary gland secretion 5 http://flybase.net/reports/FBgn0003375.html FBgn0063132 protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "LP02306, SGS-5, Sgs, BcDNA:LP02306, CG7596, Sgs-5, sgs5" CG7596 16-Dec-15 2015_12 larval stage | late third instar larval stage embryonic/larval salivary gland

viable FBgn0053668 CG33668 http://flybase.net/reports/FBgn0053668.html protein_coding_gene CG33668 16-Dec-15 2015_12 FBgn0000475 dn http://flybase.net/reports/FBgn0000475.html gene 16-Dec-15 2015_12 "viable,reduced,heat sensitive,sterile,eye color defective" "pigment cell,testis,spermathecum,genitalia" FBgn0016844 l(1)N19 lethal (1) N19 http://flybase.net/reports/FBgn0016844.html gene N19 16-Dec-15 2015_12 "lethal,recessive" FBgn0028593 l(2)s9998 lethal (2) s9998 http://flybase.net/reports/FBgn0028593.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000640 Fbp2 Fat body protein 2 http://flybase.net/reports/FBgn0000640.html protein_coding_gene "0045735=nutrient reservoir activity, 0004022=alcohol dehydrogenase (NAD) activity" 0055114=oxidation-reduction process 0005811=lipid particle "fat body protein P6, Protein-6, P6, CG3763, Fbp-2, T19" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002424=Alcohol dehydrogenase, insect-type, IPR002426=Alcohol dehydrogenase, Ceratitis-type" CG3763 16-Dec-15 2015_12 "ENSDARG00000026236(zgc:56585),ENSDARG00000012016(LOC565975)" ENSXETG00000016904(hpgd) ENSG00000164120(HPGD) " prepupal stage , larval stage | third instar " "viable,visible" trichogen cell FBgn0025783 anon-MMS35 anon-MMS35 http://flybase.net/reports/FBgn0025783.html gene 0004364=glutathione transferase activity 16-Dec-15 2015_12 FBgn0060353 l(3)S141908 lethal (3) S141908 http://flybase.net/reports/FBgn0060353.html gene 1419/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0038945 CG5386 http://flybase.net/reports/FBgn0038945.html protein_coding_gene CG5386 16-Dec-15 2015_12 lethal FBgn0033834 CG4744 http://flybase.net/reports/FBgn0033834.html protein_coding_gene CG4744 16-Dec-15 2015_12 viable heart primordium DRSC28696 K 0.592616026 0.21847114 0.449421079 0.138939399 0.12822044 1.929923116 FBgn0033736 CG13154 http://flybase.net/reports/FBgn0033736.html protein_coding_gene CG13154 16-Dec-15 2015_12 viable FBgn0034978 CG3257 http://flybase.net/reports/FBgn0034978.html FBgn0027764 protein_coding_gene anon-EST:Posey117 CG3257 16-Dec-15 2015_12 "visible,planar polarity defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0016929 smi28E smell impaired 28E http://flybase.net/reports/FBgn0016929.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0051677 CG31677 http://flybase.net/reports/FBgn0051677.html protein_coding_gene CG31677 16-Dec-15 2015_12 viable FBgn0036977 CG5665 http://flybase.net/reports/FBgn0036977.html protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" 0016042=lipid catabolic process cg5665 "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG5665 16-Dec-15 2015_12 DRSC11783 IE 1.944524509 -0.45976208 2.518269033 -0.054907318 -0.223123894 1.469520795 FBgn0029987 CG15330 http://flybase.net/reports/FBgn0029987.html protein_coding_gene 0046331=lateral inhibition CG15330 16-Dec-15 2015_12 "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0085676 CG41537 http://flybase.net/reports/FBgn0085676.html FBan0041537 protein_coding_gene 16-Dec-15 2015_12 FBgn0266173 pre-mod(mdg4)-K http://flybase.net/reports/FBgn0266173.html protein_coding_gene CG44879 "IPR007588=Zinc finger, FLYWCH-type" CG44879 16-Dec-15 2015_12 FBgn0038665 CG12269 http://flybase.net/reports/FBgn0038665.html protein_coding_gene IPR003033=SCP2 sterol-binding domain CG12269 16-Dec-15 2015_12 viable FBgn0083987 snRNA:U11 small nuclear RNA U11 http://flybase.net/reports/FBgn0083987.html "FBgn0053708, FBgn0065106, FBgn0083061" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005689=U12-type spliceosomal complex "U11, snmRNA:149, dU11 snRNA, Dm-149, CR34151, CR33708, small non-messenger RNA 149, 63E-F U11" CR34151 16-Dec-15 2015_12 FBgn0011110 l(1)Q71b lethal (1) Q71b http://flybase.net/reports/FBgn0011110.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0029629 eIF3ga eIF3g paralogue a http://flybase.net/reports/FBgn0029629.html protein_coding_gene "0003743=translation initiation factor activity, 0003729=mRNA binding, 0000166=nucleotide binding, 0008270=zinc ion binding" "0000022=mitotic spindle elongation, 0006413=translational initiation, 0051726=regulation of cell cycle, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division" 0005852=eukaryotic translation initiation factor 3 complex "eIF3-S4, eIF s4, CG8636, cg8636, eIF-3" "IPR000504=RNA recognition motif domain, IPR024675=Eukaryotic translation initiation factor 3 subunit G, N-terminal, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR001878=Zinc finger, CCHC-type, IPR017334=Eukaryotic translation initiation factor 3 subunit G" CG8636 16-Dec-15 2015_12 ENSDARG00000016889(eif3g) YDR429C(TIF35) WBGene00001230(eif-3.G) ENSXETG00000027008(eif3s4) ENSMUSG00000070319(Eif3g) ENSG00000130811(EIF3G) lethal DRSC18427 IE 1.803190799 -1.112372353 -6.283402272 -5.485621521 0.231490839 0.647321104 FBgn0260477 CG30283 http://flybase.net/reports/FBgn0260477.html "FBgn0050283, FBgn0034635" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG10450, SPH37, SP37" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG30283 16-Dec-15 2015_12 viable FBgn0015586 Acp76A Accessory gland protein 76A http://flybase.net/reports/FBgn0015586.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "Accessory gland-specific peptide 76A, Accessory gland protein 76A, Spn76A, Acp76, CG3801" "IPR000215=Serpin family, IPR023795=Serpin, conserved site, IPR023796=Serpin domain" CG3801 16-Dec-15 2015_12 adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0264426 CG43844 http://flybase.net/reports/FBgn0264426.html protein_coding_gene CR43844 CG43844 16-Dec-15 2015_12 FBgn0038133 Osi22 Osiris 22 http://flybase.net/reports/FBgn0038133.html protein_coding_gene 0005887=integral component of plasma membrane "CG8644, Osiris" CG8644 16-Dec-15 2015_12 FBgn0266786 CR45251 http://flybase.net/reports/FBgn0266786.html non_protein_coding_gene CR45251 16-Dec-15 2015_12 FBgn0034994 Ir60a Ionotropic receptor 60a http://flybase.net/reports/FBgn0034994.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 60a, IR60a, CG13576, DmelIR60a" CG13576 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0034545 CG13438 http://flybase.net/reports/FBgn0034545.html protein_coding_gene CG13438 16-Dec-15 2015_12 viable FBgn0027082 Aats-pro Prolyl-tRNA synthetase http://flybase.net/reports/FBgn0027082.html FBgn0035361 protein_coding_gene "0004827=proline-tRNA ligase activity, 0004820=glycine-tRNA ligase activity, 0005524=ATP binding" "0006433=prolyl-tRNA aminoacylation, 0006426=glycyl-tRNA aminoacylation" 0005737=cytoplasm "ProRS, PRS, CG12186" "IPR002316=Proline-tRNA ligase, class IIa, IPR002315=Glycyl-tRNA synthetase, IPR002314=Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR004500=Prolyl-tRNA synthetase, class IIa, bacterial-type, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR004154=Anticodon-binding" CG12186 16-Dec-15 2015_12 ENSDARG00000044404(pars2) YER087W(AIM10) WBGene00004190(pars-2) ENSXETG00000020007(PARS2) ENSMUSG00000043572(Pars2) ENSG00000162396(PARS2) embryonic stage

ubiquitous "viable,decreased cell size,cell autonomous,somatic clone" lysosome & larval fat body | somatic clone | cell autonomous FBgn0001331 K230 K230 http://flybase.net/reports/FBgn0001331.html gene 0005096=GTPase activator activity 16-Dec-15 2015_12 FBgn0020385 pug pugilist http://flybase.net/reports/FBgn0020385.html protein_coding_gene "0004329=formate-tetrahydrofolate ligase activity, 0004477=methenyltetrahydrofolate cyclohydrolase activity, 0005524=ATP binding, 0004488=methylenetetrahydrofolate dehydrogenase (NADP+) activity" "0055114=oxidation-reduction process, 0009396=folic acid-containing compound biosynthetic process, 0006730=one-carbon metabolic process" "0005811=lipid particle, 0005829=cytosol, 0005737=cytoplasm" "Pugilist, pugD, CG4067, Pug, bs14h02.y1, MTHFD" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020867=Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site, IPR020631=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, IPR016040=NAD(P)-binding domain, IPR000672=Tetrahydrofolate dehydrogenase/cyclohydrolase, IPR020630=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, IPR000559=Formate-tetrahydrofolate ligase, FTHFS, IPR020628=Formate-tetrahydrofolate ligase, FTHFS, conserved site" CG4067 16-Dec-15 2015_12 ENSDARG00000040492(mthfd1) "YBR084W(MIS1),YGR204W(ADE3)" WBGene00019492(K07E3.4) ENSXETG00000013956(MTHFD1L) ENSMUSG00000021048(Mthfd1) ENSG00000100714(MTHFD1) "wild-type,visible,recessive,viable,eye color defective,dominant" "eye,pigment cell" FBgn0067303 DDB2 DDB2 http://flybase.net/reports/FBgn0067303.html gene 16-Dec-15 2015_12 FBgn0034430 mip40 Myb-interacting protein 40 http://flybase.net/reports/FBgn0034430.html protein_coding_gene "0007283=spermatogenesis, 0048477=oogenesis, 0007307=eggshell chorion gene amplification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007049=cell cycle" "0031523=Myb complex, 0017053=transcriptional repressor complex" "p40, Mip40, CG15119" IPR028226=Protein LIN37 CG15119 16-Dec-15 2015_12 "ENSDARG00000053950(lin37),ENSDARG00000068696" ENSXETG00000017560(Q66JK6_XENTR) ENSMUSG00000036845(Lin37) ENSG00000188223(LIN37) "viable,female sterile,recessive,male sterile,meiotic cell cycle defective,male" testis DRSC06541 IE 2.546585413 -0.064869528 2.922653321 -1.284611315 1.335397368 -0.139723932 FBgn0262582 cic capicua http://flybase.net/reports/FBgn0262582.html "FBgn0028386, FBgn0010023, FBgn0038782, FBgn0038780" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0003712=transcription cofactor activity, 0070491=repressing transcription factor binding" "0030308=negative regulation of cell growth, 0007362=terminal region determination, 0007474=imaginal disc-derived wing vein specification, 0048190=wing disc dorsal/ventral pattern formation, 0046843=dorsal appendage formation, 0001700=embryonic development via the syncytial blastoderm, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated, 0048592=eye morphogenesis" 0005634=nucleus "E(Dl)D49, Enhancer of Delta D49, fet, capicua, fettucine, CIC, CG5060, Capicua, Cic, CG5067, CG43122, cics, CAPICUA" IPR009071=High mobility group box domain CG43122 16-Dec-15 2015_12 "ENSDARG00000055502,ENSDARG00000071150(LOC560336)" WBGene00001560(gei-3) ENSMUSG00000005442(Cic) ENSG00000079432(CIC) embryonic stage | early embryonic stage | early organism | 10-90% egg length

FBgn0013489 l(1)6PP7 lethal (1) 6PP7 http://flybase.net/reports/FBgn0013489.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0024839 rk(2)364 rk(2)364 http://flybase.net/reports/FBgn0024839.html gene 16-Dec-15 2015_12 FBgn0011023 l(3)s2253 lethal (3) s2253 http://flybase.net/reports/FBgn0011023.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069157 mcl(3)Z2566 mcl(3)Z2566 http://flybase.net/reports/FBgn0069157.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0001089 Gal ë_ galactosidase http://flybase.net/reports/FBgn0001089.html FBgn0031761 protein_coding_gene 0004565=beta-galactosidase activity 0005975=carbohydrate metabolic process 0005764=lysosome "beta-gal, beta galactosidase, beta-GAL, lacZ-1, gal, beta-galactosidase-1, beta-Gal-1, CG9092" "IPR013781=Glycoside hydrolase, catalytic domain, IPR031330=Glycoside hydrolase 35, catalytic domain, IPR001944=Glycoside hydrolase, family 35, IPR017853=Glycoside hydrolase superfamily, IPR026283=Beta-galactosidase 1-like, IPR008979=Galactose-binding domain-like" CG9092 16-Dec-15 2015_12 "ENSDARG00000036415(glb1),ENSDARG00000029955(glb1l)" "WBGene00011832(T19B10.3),WBGene00019225(H22K11.2)" "ENSXETG00000015609(glb1),ENSXETG00000019291(BC084140.1)" "ENSMUSG00000045594(Glb1),ENSMUSG00000026200" "ENSG00000170266(GLB1),ENSG00000163521(GLB1L)" " adult stage , pupal stage " " pupal stage , adult stage " FBgn0034493 CG8908 http://flybase.net/reports/FBgn0034493.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "IPR026082=ABC transporter A, ABCA, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8908 16-Dec-15 2015_12 "viable,fertile" FBgn0259098 CG42246 http://flybase.net/reports/FBgn0259098.html protein_coding_gene Dm_X:38130 CG42246 16-Dec-15 2015_12 FBgn0266275 CR44960 http://flybase.net/reports/FBgn0266275.html non_protein_coding_gene CR44960 16-Dec-15 2015_12 FBgn0260439 Pp2A-29B Protein phosphatase 2A at 29B http://flybase.net/reports/FBgn0260439.html "FBgn0005776, FBgn0032028, FBgn0053297, FBtr0079644, FBpp0079260, FBtr0079645, FBpp0079261, FBtr0079646, FBpp0079262, FBtr0079647, FBpp0079263" protein_coding_gene 0008601=protein phosphatase type 2A regulator activity "0006914=autophagy, 0007052=mitotic spindle organization, 0051225=spindle assembly, 0022008=neurogenesis, 0090307=mitotic spindle assembly, 0006470=protein dephosphorylation, 0051297=centrosome organization, 0007098=centrosome cycle, 0007059=chromosome segregation, 0051298=centrosome duplication, 0007099=centriole replication, 0006909=phagocytosis" "0000159=protein phosphatase type 2A complex, 0005737=cytoplasm, 0008287=protein serine/threonine phosphatase complex, 0005814=centriole" "Pp2A29B, PP2A-A, CG33297, CG13383, CG17291, 29B, protein phosphatase 2A, A/PR65, Pp2A, PP2A A, regulatory subunit A of type 2A protein phosphatase, pp2A-29B, PP2A, PR65, DPR65, PP2A 65kD subunit A, dPP2A A, protein phosphatase 2A at 29B, PP2A 29B, PP2A-29B, 65 kDa regulatory subunit of protein phosphatase, PP2A[A]" "IPR000357=HEAT repeat, IPR021133=HEAT, type 2, IPR031090=Serine/threonine-protein phosphatase 2A subunit A, metazoa, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG17291 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage , adult stage && oogenesis stage , embryonic stage&&larval stage&&adult stage , embryonic stage | early , embryonic stage | late , embryonic stage | stage 9-11 , adult stage " " imaginal disc

,

ubiquitous , oocyte

, larval brain

, gonad

, neuroblast

, supraesophageal ganglion

, nurse cell

, embryonic/larval salivary gland

, adult brain

, ventral nerve cord

, adult midgut

" "lethal,recessive,neuroanatomy defective,viable,visible" "neuroblast,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum,synapse,neuromuscular junction,wing margin" FBgn0265995 CR44770 http://flybase.net/reports/FBgn0265995.html non_protein_coding_gene lincRNA.145 CR44770 16-Dec-15 2015_12 FBgn0036869 CG14094 http://flybase.net/reports/FBgn0036869.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263078 CG43339 http://flybase.net/reports/FBgn0263078.html "FBgn0263044, FBgn0261350, FBan0031791, FBgn0086682" protein_coding_gene "CG31791, CG42627" CG43339 16-Dec-15 2015_12 FBgn0038948 PSR phosphatidylserine receptor http://flybase.net/reports/FBgn0038948.html FBgn0042088 protein_coding_gene 0070815=peptidyl-lysine 5-dioxygenase activity "0046329=negative regulation of JNK cascade, 0035212=cell competition in a multicellular organism, 0043066=negative regulation of apoptotic process, 0018395=peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine" 0005634=nucleus "CG5383, phosphatidyl-serine receptor, dPSR, PS, L0022859, psr, BEST:LD22859, Psr" IPR003347=JmjC domain CG5383 16-Dec-15 2015_12 ENSDARG00000034358(jmjd6) WBGene00004205(psr-1) ENSXETG00000019501(JMJD6) ENSMUSG00000056962(Jmjd6) ENSG00000070495(JMJD6) "viable,fertile,visible,male" "ommatidium,male genitalia,wing,eye disc,trichogen cell" FBgn0060512 l(3)S104104 lethal (3) S104104 http://flybase.net/reports/FBgn0060512.html gene 1041/04 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0002513 l(3)Sp5 lethal (3) Sp5 http://flybase.net/reports/FBgn0002513.html gene 16-Dec-15 2015_12 lethal FBgn0038612 cona corona http://flybase.net/reports/FBgn0038612.html protein_coding_gene "0007130=synaptonemal complex assembly, 0007129=synapsis" 0000795=synaptonemal complex CG7676 CG7676 16-Dec-15 2015_12 viable FBgn0267745 CR46076 http://flybase.net/reports/FBgn0267745.html non_protein_coding_gene lincRNA.875 CR46076 16-Dec-15 2015_12 FBgn0261704 CG42740 http://flybase.net/reports/FBgn0261704.html protein_coding_gene CG42740 16-Dec-15 2015_12 FBgn0034499 Cpr56F Cuticular protein 56F http://flybase.net/reports/FBgn0034499.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG9036, DmelCpr56F" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG9036 16-Dec-15 2015_12 "viable,fertile" FBgn0265925 CR44714 http://flybase.net/reports/FBgn0265925.html non_protein_coding_gene CR44714 16-Dec-15 2015_12 FBgn0001140 grotle grotle http://flybase.net/reports/FBgn0001140.html gene "grottle, gr, grt" 16-Dec-15 2015_12 "visible,dominant" "wing,posterior cell" FBgn0275432 CR46264 http://flybase.net/reports/FBgn0275432.html non_protein_coding_gene CR46264 16-Dec-15 2015_12 FBgn0011042 l(1)Stark-a lethal (1) of Stark a http://flybase.net/reports/FBgn0011042.html FBgn0010212 gene "lethal (1) Sa, l(1)Sa" 16-Dec-15 2015_12 lethal FBgn0010891 l(3)06487 lethal (3) 06487 http://flybase.net/reports/FBgn0010891.html gene 6487 16-Dec-15 2015_12 "lethal,recessive" FBgn0260281 GSd455 http://flybase.net/reports/FBgn0260281.html gene 16-Dec-15 2015_12 lethal FBgn0034477 CG13872 http://flybase.net/reports/FBgn0034477.html protein_coding_gene CG13872 16-Dec-15 2015_12 viable FBgn0265038 CR44155 http://flybase.net/reports/FBgn0265038.html non_protein_coding_gene CR44155 16-Dec-15 2015_12 FBgn0031419 CG15390 http://flybase.net/reports/FBgn0031419.html FBgn0063688 protein_coding_gene 0003690=double-stranded DNA binding "0006355=regulation of transcription, DNA-templated" 0005739=mitochondrion BcDNA:RE18748 IPR003690=Mitochodrial transcription termination factor CG15390 16-Dec-15 2015_12 viable FBgn0030570 CG12540 http://flybase.net/reports/FBgn0030570.html FBgn0047102 protein_coding_gene BcDNA:RE49992 CG12540 16-Dec-15 2015_12 FBgn0266073 CR44826 http://flybase.net/reports/FBgn0266073.html non_protein_coding_gene CR44826 16-Dec-15 2015_12 FBgn0259179 CG42284 http://flybase.net/reports/FBgn0259179.html "FBgn0050264, FBgn0034780, FBgn0050266, FBgn0034779" protein_coding_gene "CG13528, CG30266, CG30264, CG13529" "IPR007858=Dpy-30 motif, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG42284 16-Dec-15 2015_12 WBGene00009376 "ENSMUSG00000029517(Ankrd7),ENSMUSG00000070396(Gm16475),ENSMUSG00000026774(4931423N10Rik),ENSMUSG00000074453(4930467E23Rik),ENSMUSG00000074251(Gm7827)" FBgn0039207 CG5789 http://flybase.net/reports/FBgn0039207.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0008559=xenobiotic-transporting ATPase activity, 0005524=ATP binding" 0055085=transmembrane transport 0043190=ATP-binding cassette (ABC) transporter complex Dme_CG5789 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain" CG5789 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0013383 acj7 abnormal-chemosensory-jump-7 http://flybase.net/reports/FBgn0013383.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive" FBgn0259939 ttd1 TRPL translocation defect 1 http://flybase.net/reports/FBgn0259939.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003914 U Upturned http://flybase.net/reports/FBgn0003914.html gene 16-Dec-15 2015_12 "visible,dominant,lethal,recessive,viable,eye color defective,body color defective" "wing,posterior scutellar bristle,cuticle" FBgn0000041 act actidione-sensitive http://flybase.net/reports/FBgn0000041.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0001903 l(2)22Ad lethal (2) 22Ad http://flybase.net/reports/FBgn0001903.html gene "l(2)neh-17, l(2)neh17" 16-Dec-15 2015_12 lethal FBgn0263961 BG01700 http://flybase.net/reports/FBgn0263961.html gene 16-Dec-15 2015_12 "long lived,starvation stress response defective,male limited,temperature response defective,gravitaxis defective" FBgn0031217 CG11377 http://flybase.net/reports/FBgn0031217.html protein_coding_gene 0005509=calcium ion binding CT31762 "IPR002049=Laminin EGF domain, IPR006212=Furin-like repeat, IPR013032=EGF-like, conserved site, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR021852=Domain of unknown function DUF3456, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG11377 16-Dec-15 2015_12 "ENSDARG00000029071(LOC100331781),ENSDARG00000006990" WBGene00008624(F09E8.2) "ENSXETG00000014527(CRELD2),ENSXETG00000023532()" "ENSMUSG00000030284(Creld1),ENSMUSG00000023272(Creld2)" "ENSG00000163703(CRELD1),ENSG00000184164(CRELD2)" FBgn0043048 anon-60Ae anon-60Ae http://flybase.net/reports/FBgn0043048.html gene 16-Dec-15 2015_12 FBgn0044111 E(rst)C329 E(rst)C329 http://flybase.net/reports/FBgn0044111.html gene 0001745=compound eye morphogenesis C329 16-Dec-15 2015_12 viable FBgn0001299 kdu kudu http://flybase.net/reports/FBgn0001299.html gene 16-Dec-15 2015_12 female sterile egg FBgn0262379 mir-1012 mir-1012 stem loop http://flybase.net/reports/FBgn0262379.html "FBgn0250808, FBgn0262195" miRNA_gene "CR42902, dme-mir-1012, miR-1012" CR42902 16-Dec-15 2015_12 "visible,viable,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin,1st posterior cell" FBgn0024289 Sodh-1 Sorbitol dehydrogenase 1 http://flybase.net/reports/FBgn0024289.html protein_coding_gene "0003939=L-iditol 2-dehydrogenase activity, 0008270=zinc ion binding, 0016491=oxidoreductase activity" 0055114=oxidation-reduction process "DM_7298873, Sdh-1, CG1982, Sorbitol dehydrogenase like, Sodh, BG:DS00464.2" "IPR011032=GroES-like, IPR013154=Alcohol dehydrogenase, N-terminal, IPR013149=Alcohol dehydrogenase, C-terminal, IPR016040=NAD(P)-binding domain, IPR002328=Alcohol dehydrogenase, zinc-type, conserved site, IPR002085=Alcohol dehydrogenase superfamily, zinc-type" CG1982 16-Dec-15 2015_12 ENSDARG00000053405 "YJR159W(SOR1),YDL246C(SOR2),YLR070C(XYL2)" "WBGene00011004(R04B5.6),WBGene00011003(R04B5.5)" ENSXETG00000023897(sord) ENSMUSG00000027227(Sord) ENSG00000140263(SORD) " larval stage , pupal stage , adult stage " viable FBgn0054044 CR34044 http://flybase.net/reports/FBgn0054044.html FBgn0082853 non_protein_coding_gene "BP1053, CG34044, unnamed" CR34044 16-Dec-15 2015_12 FBgn0029016 l(3)77CDi lethal (3) 77CDi http://flybase.net/reports/FBgn0029016.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0036648 CG4098 http://flybase.net/reports/FBgn0036648.html protein_coding_gene 0016787=hydrolase activity "CG4098-PA, unnamed" "IPR000086=NUDIX hydrolase domain, IPR015797=NUDIX hydrolase domain-like" CG4098 16-Dec-15 2015_12 ENSDARG00000070572 WBGene00003583(ndx-6) ENSMUSG00000029310(Nudt9) ENSG00000170502(NUDT9) viable FBgn0259932 CG42455 http://flybase.net/reports/FBgn0259932.html protein_coding_gene Dromel_CG11989_FBtr0076348_ard1_uORF CG42455 16-Dec-15 2015_12 FBgn0004381 Klp68D Kinesin-like protein at 68D http://flybase.net/reports/FBgn0004381.html protein_coding_gene "0008017=microtubule binding, 0003774=motor activity, 0003777=microtubule motor activity, 0005524=ATP binding" "0030951=establishment or maintenance of microtubule cytoskeleton polarity, 0007608=sensory perception of smell, 0007018=microtubule-based movement, 0008089=anterograde axon cargo transport" "0005873=plus-end kinesin complex, 0005871=kinesin complex" "kinesin II, KIF3B, Klp5, Kinesin-2, KLP68Ddm, klp68d, KLP-5, kinesin-2, DmKlp68D, KLP68D, KLP[[64D/68D]], CG7293, KIF 3B, KLP5" "IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain" CG7293 16-Dec-15 2015_12 "ENSDARG00000012081(kif3b),ENSDARG00000053898,ENSDARG00000017162" YEL061C(CIN8) "ENSXETG00000016636(KIF3B),ENSXETG00000024790(KIF3C)" "ENSMUSG00000027475(Kif3b),ENSMUSG00000020668(Kif3c)" "ENSG00000101350(KIF3B),ENSG00000084731(KIF3C)" " embryonic stage -- adult stage , adult stage , adult stage | male , adult stage | female " " head

, testis

, ovary

" "viable,fertile,neurophysiology defective,auditory perception defective,neuroanatomy defective,lethal,partially lethal - majority die,visible,recessive" "sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,cilium,trichogen cell,mesothoracic tergum" FBgn0069351 Sryip Sryip http://flybase.net/reports/FBgn0069351.html gene 0045197=establishment or maintenance of epithelial cell apical/basal polarity 16-Dec-15 2015_12 FBgn0261108 Atg13 Autophagy-related 13 http://flybase.net/reports/FBgn0261108.html "FBgn0259122, FBgn0037582, FBgn0047245" protein_coding_gene "0005515=protein binding, 0019887=protein kinase regulator activity" "0010506=regulation of autophagy, 0006914=autophagy, 0032147=activation of protein kinase activity, 0045850=positive regulation of nurse cell apoptotic process, 0035096=larval midgut cell programmed cell death" 0034273=ATG1/UKL1 signaling complex "BcDNA:HL01508, atg13, Autophagy-specific gene 13, CG7331, ATG13" IPR018731=Autophagy-related protein 13 CG7331 16-Dec-15 2015_12 ENSDARG00000036040(atg13) ENSXETG00000001983(KIAA0652) ENSMUSG00000027244(Atg13) ENSG00000175224(ATG13) FBgn0065603 l(2)SH0862 lethal (2) SH0862 http://flybase.net/reports/FBgn0065603.html gene l(2)SH2 0862 16-Dec-15 2015_12 "lethal,recessive" FBgn0002713 mei-S8 meiotic from via Salaria 8 http://flybase.net/reports/FBgn0002713.html gene "0007141=male meiosis I, 0007140=male meiosis" meiS8 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive" spermatocyte & nuclear chromosome FBgn0002009 l(2)36Fb lethal (2) 36Fb http://flybase.net/reports/FBgn0002009.html gene l(2)E70 16-Dec-15 2015_12 lethal FBgn0035321 CG1275 http://flybase.net/reports/FBgn0035321.html FBgn0062138 protein_coding_gene 0009055=electron carrier activity "0016021=integral component of membrane, 0030133=transport vesicle" "anon-WO0118547.260, Cyt-b561-1, DcytB-like, cytochrome [[b561-1]]" "IPR004877=Cytochrome b561 domain, IPR006593=Cytochrome b561/ferric reductase transmembrane" CG1275 16-Dec-15 2015_12 ENSDARG00000038176(LOC568765) WBGene00010131(F55H2.5) ENSXETG00000018825(cybrd1) "ENSMUSG00000027015,ENSMUSG00000034445(Cybasc3)" ENSG00000071967(CYBRD1) "viable,fertile,body color defective" mesothoracic tergum DRSC08294 E 0.537476278 -0.346894408 -2.182554256 -0.211176242 0.950471043 0.033645959 FBgn0041630 Hexo1 Hexosaminidase 1 http://flybase.net/reports/FBgn0041630.html FBgn0035527 protein_coding_gene "0016231=beta-N-acetylglucosaminidase activity, 0004563=beta-N-acetylhexosaminidase activity" "0006491=N-glycan processing, 0006517=protein deglycosylation, 0016063=rhodopsin biosynthetic process" 0005886=plasma membrane "CG1318, DmHex1, hexosaminidase 1, HEX1, HEX 1, HEXO1" "IPR029018=Chitobiase/beta-hexosaminidase domain 2-like, IPR025705=Beta-hexosaminidase, IPR029019=Beta-hexosaminidase, eukaryotic type, N-terminal, IPR017853=Glycoside hydrolase superfamily, IPR015883=Glycoside hydrolase family 20, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain" CG1318 16-Dec-15 2015_12 "ENSDARG00000034368(hexa),ENSDARG00000052113(zgc:112084)" WBGene00020509(hex-1) ENSXETG00000005075(HEXB) "ENSMUSG00000025232(Hexa),ENSMUSG00000021665(Hexb)" "ENSG00000213614(HEXA),ENSG00000049860(HEXB)" "viable,fertile" FBgn0050447 CG30447 http://flybase.net/reports/FBgn0050447.html protein_coding_gene CG30447 16-Dec-15 2015_12 viable FBgn0028339 l(1)G0242 lethal (1) G0242 http://flybase.net/reports/FBgn0028339.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023067 l(1)20Aj lethal (1) 20Aj http://flybase.net/reports/FBgn0023067.html gene 1200E7b 16-Dec-15 2015_12 "lethal,recessive" FBgn0026564 CG1162 http://flybase.net/reports/FBgn0026564.html protein_coding_gene "ORF1, BG:DS00276.8" 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0014333 l(3)ry99 lethal (3) ry99 http://flybase.net/reports/FBgn0014333.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032338 CG16854 http://flybase.net/reports/FBgn0032338.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process gi7297815 "IPR004245=Protein of unknown function DUF229, IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG16854 16-Dec-15 2015_12 "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0002343 l(3)87Bl lethal (3) 87Bl http://flybase.net/reports/FBgn0002343.html gene l(3)ck24 16-Dec-15 2015_12 lethal FBgn0020800 negro negro http://flybase.net/reports/FBgn0020800.html gene ne 16-Dec-15 2015_12 body color defective FBgn0065414 l(2)SH1557 lethal (2) SH1557 http://flybase.net/reports/FBgn0065414.html gene l(2)SH2 1557 16-Dec-15 2015_12 "lethal,recessive" FBgn0266421 RPA3 Replication protein A3 http://flybase.net/reports/FBgn0266421.html "FBgn0030322, FBgn0062930, FBgn0027257" protein_coding_gene 0003677=DNA binding "0022008=neurogenesis, 0006281=DNA repair, 0006260=DNA replication, 0006310=DNA recombination, 0097150=neuronal stem cell maintenance" "0005662=DNA replication factor A complex, 0005634=nucleus" "lethal (1) G0241, CG15220, replication protein A, l(1)G0241, BcDNA:RH55360" "IPR012340=Nucleic acid-binding, OB-fold, IPR013970=Replication factor A protein 3" CG15220 16-Dec-15 2015_12 ENSG00000106399(RPA3) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,recessive,lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,lamina anlage,medulla anlage,larval outer optic anlage,somatic clone" FBgn0041834 Eth-AR308 Eth-AR308 http://flybase.net/reports/FBgn0041834.html gene Eth[AR]308 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0039564 CG5527 http://flybase.net/reports/FBgn0039564.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR018497=Peptidase M13, C-terminal domain" CG5527 16-Dec-15 2015_12 FBgn0035686 Cpr65Az Cuticular protein 65Az http://flybase.net/reports/FBgn0035686.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG12330, DmelCpr65Az" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG12330 16-Dec-15 2015_12 viable FBgn0263203 T:Mito-Tom20 Mitochondrial targeting motif of Tom20 http://flybase.net/reports/FBgn0263203.html engineered_tag T:Tom20 16-Dec-15 2015_12 FBgn0010692 l(2)s3997 lethal (2) s3997 http://flybase.net/reports/FBgn0010692.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0036956 CG13813 http://flybase.net/reports/FBgn0036956.html protein_coding_gene "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG13813 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" viable FBgn0065214 l(2)SH2255 lethal (2) SH2255 http://flybase.net/reports/FBgn0065214.html gene l(2)SH2 2255 16-Dec-15 2015_12 "lethal,recessive" FBgn0003637 su(vg) suppressor of vestigial http://flybase.net/reports/FBgn0003637.html gene 16-Dec-15 2015_12 FBgn0067874 Mod(Prat:bw)3-12 Mod(Prat:bw)3-12 http://flybase.net/reports/FBgn0067874.html gene Mod-3-12 16-Dec-15 2015_12 suppressor of variegation FBgn0054033 CG34033 http://flybase.net/reports/FBgn0054033.html FBgn0082662 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "HDC05479, unnamed, BP1078" "IPR016187=C-type lectin fold, IPR001304=C-type lectin, IPR016186=C-type lectin-like" CG34033 16-Dec-15 2015_12 "ENSXETG00000028030(),ENSXETG00000028032(),ENSXETG00000012995(),ENSXETG00000028033(),ENSXETG00000010164(LAYN),ENSXETG00000010225()" FBgn0030493 CG15756 http://flybase.net/reports/FBgn0030493.html protein_coding_gene "0042302=structural constituent of cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix IPR000618=Insect cuticle protein CG15756 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0002115 l(2)bw lethal (2) bw http://flybase.net/reports/FBgn0002115.html gene 16-Dec-15 2015_12 lethal FBgn0005020 dke dark eye http://flybase.net/reports/FBgn0005020.html gene dke-c 16-Dec-15 2015_12 eye color defective pigment cell FBgn0065584 l(2)SH0921 lethal (2) SH0921 http://flybase.net/reports/FBgn0065584.html gene l(2)SH2 0921 16-Dec-15 2015_12 "lethal,recessive" FBgn0036485 FucTA FucTA http://flybase.net/reports/FBgn0036485.html FBgn0027695 protein_coding_gene "0018392=glycoprotein 3-alpha-L-fucosyltransferase activity, 0008417=fucosyltransferase activity, 0046920=alpha-(1->3)-fucosyltransferase activity, 0033932=1,3-alpha-L-fucosidase activity" "0006486=protein glycosylation, 0036071=N-glycan fucosylation, 0007399=nervous system development" "0005797=Golgi medial cisterna, 0016020=membrane" "core fucosyltransferase, Dm alpha1,3-FucT, alpha1,3-fucosyltransferase, core alpha1,3-fucosyltransferase, fucTA, anon-EST:Posey285, CG6869" IPR001503=Glycosyl transferase family 10 CG6869 16-Dec-15 2015_12 "ENSDARG00000016460(LOC796410),ENSDARG00000042643,ENSDARG00000070979,ENSDARG00000039939,ENSDARG00000059055(ft2),ENSDARG00000067708,ENSDARG00000039608(zgc:112433),ENSDARG00000058299,ENSDARG00000067524,ENSDARG00000027699,ENSDARG00000059056(ft1),ENSDARG00000028098(zgc:162337),ENSDARG00000057350,ENSDARG00000067709,ENSDARG00000069408,ENSDARG00000044775(fut7)" "WBGene00001507(fut-4),WBGene00020222(fut-6),WBGene00043986(fut-5)" "ENSXETG00000008818(),ENSXETG00000027089(),ENSXETG00000006041(fut3),ENSXETG00000027088(),ENSXETG00000027921(),ENSXETG00000001061(fut9),ENSXETG00000025292(fut4)" "ENSMUSG00000036587(Fut7),ENSMUSG00000049307(Fut4),ENSMUSG00000055373(Fut9)" "ENSG00000156413(FUT6),ENSG00000130383,ENSG00000171124(FUT3),ENSG00000180549(FUT7),ENSG00000196371(FUT4),ENSG00000172461(FUT9)" "viable,fertile,neuroanatomy defective,visible" "ventral nerve cord,embryonic/larval glial cell,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,wing margin,anterior crossvein,mesothoracic tergum" FBgn0034766 Obp59a Odorant-binding protein 59a http://flybase.net/reports/FBgn0034766.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "59a, DmelObp59a, CG13517, Obp58a" IPR006170=Pheromone/general odorant binding protein CG13517 16-Dec-15 2015_12 viable FBgn0264547 CR43926 http://flybase.net/reports/FBgn0264547.html non_protein_coding_gene CR43926 16-Dec-15 2015_12 FBgn0034001 mRpL41 mitochondrial ribosomal protein L41 http://flybase.net/reports/FBgn0034001.html FBgn0047156 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0030529=ribonucleoprotein complex" "CG12954, YmL27, BcDNA:RE19416" "IPR019189=Ribosomal protein L27/L41, mitochondrial" CG12954 16-Dec-15 2015_12 ENSDARG00000002264(mrpl41) ENSXETG00000003968(MRPL41) ENSMUSG00000036850(Mrpl41) "viable,visible" trichogen cell FBgn0040685 CG12587 http://flybase.net/reports/FBgn0040685.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0022338 dnk deoxyribonucleoside kinase http://flybase.net/reports/FBgn0022338.html protein_coding_gene "0004797=thymidine kinase activity, 0016301=kinase activity, 0005524=ATP binding, 0019136=deoxynucleoside kinase activity" "0016310=phosphorylation, 0006165=nucleoside diphosphate phosphorylation, 0046939=nucleotide phosphorylation, 0006230=TMP biosynthetic process" "0005737=cytoplasm, 0005739=mitochondrion" "DM-dNK, dNK, kinase, deoxynucleoside kinase, DNK, Dm-dNK, DmdNK, 2'-deoxynucleoside kinase, deoxyribonucleoside, CG5452" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR002624=Deoxynucleoside kinase, IPR031314=Deoxynucleoside kinase domain" CG5452 16-Dec-15 2015_12 ENSDARG00000046127(tk2) ENSXETG00000011228(tk2) ENSMUSG00000035824(Tk2) ENSG00000166548(TK2) "locomotor behavior defective,viable" FBgn0031086 fd19B forkhead domain 19B http://flybase.net/reports/FBgn0031086.html protein_coding_gene "0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0007346=regulation of mitotic cell cycle, 0045665=negative regulation of neuron differentiation, 0009953=dorsal/ventral pattern formation, 0009792=embryo development ending in birth or egg hatching, 0048665=neuron fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0016199=axon midline choice point recognition, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0002052=positive regulation of neuroblast proliferation, 0007380=specification of segmental identity, head, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0022008=neurogenesis, 0009888=tissue development, 0045787=positive regulation of cell cycle, 0035058=nonmotile primary cilium assembly" "0005667=transcription factor complex, 0005634=nucleus" "fd19B, Dmcg9571, CG9571" "IPR001766=Fork head domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG9571 16-Dec-15 2015_12 "ENSG00000198815(FOXJ3),ENSG00000065970(FOXJ2)" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0259581 GG01303 http://flybase.net/reports/FBgn0259581.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0083013 snoRNA:ë¬28S-1060 snoRNA:ë¬28S-1060 http://flybase.net/reports/FBgn0083013.html snoRNA_gene "Psi28S-1060, psi28S-1060, Psi 28S-1060, CR34591" CR34591 16-Dec-15 2015_12 FBgn0031779 CG9175 http://flybase.net/reports/FBgn0031779.html protein_coding_gene 0003677=DNA binding "0009306=protein secretion, 0000902=cell morphogenesis" "0005634=nucleus, 0012505=endomembrane system, 0005783=endoplasmic reticulum" Sec12 "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG9175 16-Dec-15 2015_12 ENSDARG00000054897(zgc:92203) WBGene00010496(K02B12.3) ENSMUSG00000045302(Preb) ENSG00000138073(PREB) "viable,fertile" FBgn0053389 5SrRNA:CR33389 5SrRNA:CR33389 http://flybase.net/reports/FBgn0053389.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33389 CR33389 16-Dec-15 2015_12 FBgn0036417 CG7906 http://flybase.net/reports/FBgn0036417.html protein_coding_gene IPR002350=Kazal domain CG7906 16-Dec-15 2015_12 viable FBgn0022267 l(2)k00605b lethal (2) k00605b http://flybase.net/reports/FBgn0022267.html gene l(2)k00605 16-Dec-15 2015_12 "lethal,recessive" FBgn0053442 5SrRNA:CR33442 5SrRNA:CR33442 http://flybase.net/reports/FBgn0053442.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33442 CR33442 16-Dec-15 2015_12 FBgn0037397 CR1075 http://flybase.net/reports/FBgn0037397.html pseudogene_attribute CG1075 CR1075 16-Dec-15 2015_12 viable DRSC12144 K -0.162931853 0.357908652 -0.151925003 0.242523791 -1.532099172 -1.46805054 FBgn0015003 ACE1 Amplification-control-element-on-1 http://flybase.net/reports/FBgn0015003.html region 16-Dec-15 2015_12 FBgn0277419 l(3)psg15 http://flybase.net/reports/FBgn0277419.html gene psg15 16-Dec-15 2015_12 FBgn0001650 l(1)ds2 lethal (1) discs small 2 http://flybase.net/reports/FBgn0001650.html gene l(1)d.sml.-2 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033897 Rcd1 Reduction in Cnn dots 1 http://flybase.net/reports/FBgn0033897.html protein_coding_gene "0007293=germarium-derived egg chamber formation, 0060429=epithelium development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0022008=neurogenesis, 0007099=centriole replication, 0007095=mitotic G2 DNA damage checkpoint" "0044545=NSL complex, 0005634=nucleus" "Reduction in Cnn Dots 1, NSL3, non-specific lethal 3, CG8233, Nsl3, cg8233, Rcd1" "IPR026555=KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein, IPR029059=Alpha/beta hydrolase fold-5, IPR029058=Alpha/Beta hydrolase fold" CG8233 16-Dec-15 2015_12 ENSDARG00000029556(zgc:109953) WBGene00018812(F54D11.2) ENSXETG00000001247(KIAA1310) ENSMUSG00000010453(4632411B12Rik) ENSG00000114982(KIAA1310) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female sterile" "embryonic/larval neuroblast,ganglion mother cell,epithelium,female germline cyst" DRSC07116 E -0.137680091 0.256948652 0.321711811 -3.439579811 -0.795444286 -0.709817657 FBgn0264480 CR43888 http://flybase.net/reports/FBgn0264480.html non_protein_coding_gene CR43888 16-Dec-15 2015_12 FBgn0067774 fragile-locus-B fragile locus B http://flybase.net/reports/FBgn0067774.html gene 0007343=egg activation 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0046641 anon-38D.32 anon-38D.32 http://flybase.net/reports/FBgn0046641.html gene 38D.32 16-Dec-15 2015_12 FBgn0264740 CG43998 http://flybase.net/reports/FBgn0264740.html "FBgn0039127, FBgn0063768" protein_coding_gene "BcDNA:AT03227, CG13602, CR43998" IPR010754=Optic atrophy 3-like CG43998 16-Dec-15 2015_12 FBgn0085752 CR40594 http://flybase.net/reports/FBgn0085752.html FBan0040594 rRNA_gene CR40594 16-Dec-15 2015_12 FBgn0060986 l(3)S028113 lethal (3) S028113 http://flybase.net/reports/FBgn0060986.html gene 0281/13 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0261989 CG42807 http://flybase.net/reports/FBgn0261989.html "FBgn0033857, FBan0013335, FBgn0033858, FBgn0064931" protein_coding_gene "CG6183, CG13335" CG42807 16-Dec-15 2015_12 viable FBgn0005467 l(1)ts136 lethal (1) ts136 http://flybase.net/reports/FBgn0005467.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0262166 calypso calypso http://flybase.net/reports/FBgn0262166.html "FBgn0260028, FBgn0034088" protein_coding_gene "0003682=chromatin binding, 0004843=ubiquitin-specific protease activity" "0006342=chromatin silencing, 0006511=ubiquitin-dependent protein catabolic process, 0035522=monoubiquitinated histone H2A deubiquitination, 0007385=specification of segmental identity, abdomen" "0000790=nuclear chromatin, 0035517=PR-DUB complex, 0005634=nucleus" "CG8445, Calypso, Q7K5N4, BAP1, ubiquitin thiolesterase" "IPR001578=Peptidase C12, ubiquitin carboxyl-terminal hydrolase" CG8445 16-Dec-15 2015_12 ENSDARG00000063051(bap1) ENSXETG00000000091(TEgg031c22.1) ENSMUSG00000021901(Bap1) ENSG00000163930(BAP1) FBgn0011998 tRNA:V3b:84Da transfer RNA:val3b:84Da http://flybase.net/reports/FBgn0011998.html "FBan0031592, FBgn0003853, FBgn0011997, FBgn0051592, FBgn0060023" tRNA_gene "0033452=GUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3R.trna6-ValCAC, tRNA:V:CAC:AE002699-d, CR31592, valine tRNA, Val-3b, tRNA[Val][[3b]], AE002699.trna13-ValCAC, tRNA[Val3b], tRNA:val3b:84Da, tRNA:V3b" CR31592 16-Dec-15 2015_12 FBgn0019966 Khc::sif Khc::sif http://flybase.net/reports/FBgn0019966.html engineered_fusion_gene 16-Dec-15 2015_12 lethal "synapseelav.PLu,bouton,abdominal segmental nerve" FBgn0050259 CG30259 http://flybase.net/reports/FBgn0050259.html "FBgn0034765, FBgn0034767" protein_coding_gene "CG13523, CG13522" CG30259 16-Dec-15 2015_12 ENSDARG00000032005(ccdc65) ENSXETG00000009815(CCDC65) ENSMUSG00000003354(Ccdc65) ENSG00000139537(CCDC65) "viable,fertile,visible" "trichogen cell,supernumerary" FBgn0263354 CG42784 http://flybase.net/reports/FBgn0263354.html "FBgn0051846, FBgn0047322, FBgn0261855, FBgn0032527, FBgn0051847, FBgn0032528, FBgn0047243" protein_coding_gene "mdcds_2231, CG16850, CG31847, Dm_2L:67149, CR31846, CG16851, CG31846, BcDNA:HL01958, CG16850/CG31846, BcDNA:GH04046" CG42784 16-Dec-15 2015_12 DRSC22272 I -0.260193243 2.017581191 0.038612236 -0.131700202 -0.320753689 1.136056229 FBgn0028708 Mst85C Mst85C http://flybase.net/reports/FBgn0028708.html protein_coding_gene CG11993 CG11993 16-Dec-15 2015_12 adult stage | male viable DRSC16746 E 0.769796872 -0.661860353 -1.73194321 -0.013806641 0.334064922 0.627920243 FBgn0266097 CR44834 http://flybase.net/reports/FBgn0266097.html non_protein_coding_gene CR44834 16-Dec-15 2015_12 FBgn0260069 2L3390 http://flybase.net/reports/FBgn0260069.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0003099 PL(2)L4 Polygenic locus L4 wing vein http://flybase.net/reports/FBgn0003099.html gene PL(2)L4a 16-Dec-15 2015_12 FBgn0038685 CG14282 http://flybase.net/reports/FBgn0038685.html protein_coding_gene CG14282 16-Dec-15 2015_12 "viable,fertile" FBgn0060319 l(3)S147313 lethal (3) S147313 http://flybase.net/reports/FBgn0060319.html gene 1473/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000329 clw clubwing http://flybase.net/reports/FBgn0000329.html gene club wing 16-Dec-15 2015_12 "visible,recessive" wing FBgn0065456 l(2)SH1386 lethal (2) SH1386 http://flybase.net/reports/FBgn0065456.html gene l(2)SH2 1386 16-Dec-15 2015_12 "lethal,recessive" FBgn0003265 Rnase2 Ribonuclease 2 http://flybase.net/reports/FBgn0003265.html gene 0004540=ribonuclease activity acid RNase 16-Dec-15 2015_12 FBgn0038445 CG14891 http://flybase.net/reports/FBgn0038445.html protein_coding_gene 0003676=nucleic acid binding FBXL13 IPR000504=RNA recognition motif domain CG14891 16-Dec-15 2015_12 viable FBgn0065167 l(3)SH032 lethal (3) SH032 http://flybase.net/reports/FBgn0065167.html gene l(2)SH3 032 16-Dec-15 2015_12 "lethal,recessive" FBgn0262966 CG43277 http://flybase.net/reports/FBgn0262966.html protein_coding_gene 0016021=integral component of membrane CG43277 16-Dec-15 2015_12 FBgn0010104 cex central complex http://flybase.net/reports/FBgn0010104.html gene "0007628=adult walking behavior, 0048149=behavioral response to ethanol" 16-Dec-15 2015_12 "locomotor behavior defective,recessive,viable,behavior defective,neuroanatomy defective" "protocerebral bridge,fan-shaped body,ellipsoid body,nodulus" FBgn0261789 SmD2 Small ribonucleoprotein particle protein SmD2 http://flybase.net/reports/FBgn0261789.html "FBgn0250752, FBgn0037434, FBgn0064927" protein_coding_gene 0044822=poly(A) RNA binding "0022008=neurogenesis, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex" "snRNP D2, dD2, BcDNA:LD03002, SMD2_DROME, snRNP2, CG1249, Small ribonucleoprotein particle protein D2, D2-Sm" "IPR001163=LSM domain, eukaryotic/archaea-type, IPR027248=Small nuclear ribonucleoprotein Sm D2, IPR010920=LSM domain" CG1249 16-Dec-15 2015_12 "ENSDARG00000040440(snrpd2),ENSDARG00000068379" YLR275W(SMD2) WBGene00004917(snr-4) ENSXETG00000002173(snrpd2) "ENSMUSG00000040824(Snrpd2),ENSMUSG00000062678(Gm10120),ENSMUSG00000063166(Gm5449)" ENSG00000125743(SNRPD2) DRSC12536 IE -0.339903988 1.676149335 -3.723763331 -0.532462112 -0.079102399 -0.541013847 FBgn0021989 l(2)k09617 lethal (2) k09617 http://flybase.net/reports/FBgn0021989.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265577 CR44404 http://flybase.net/reports/FBgn0265577.html non_protein_coding_gene CR44404 16-Dec-15 2015_12 FBgn0020575 anon-59Cj anon-59Cj http://flybase.net/reports/FBgn0020575.html gene 16-Dec-15 2015_12 FBgn0031245 CG3625 http://flybase.net/reports/FBgn0031245.html protein_coding_gene "0012505=endomembrane system, 0016021=integral component of membrane" IPR006838=FAR-17a/AIG1-like protein CG3625 16-Dec-15 2015_12 "ENSDARG00000007171(aig1),ENSDARG00000037810(zgc:112175)" "WBGene00007995(C37E2.3),WBGene00007994(C37E2.2)" "ENSXETG00000009792(AIG1),ENSXETG00000019224(C6orf105)" ENSMUSG00000019806(Aig1) ENSG00000146416(AIG1) "visible,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum FBgn0035831 CG8038 http://flybase.net/reports/FBgn0035831.html "FBgn0046393, FBgn0063138" protein_coding_gene "0004526=ribonuclease P activity, 0003723=RNA binding" "0008033=tRNA processing, 0009267=cellular response to starvation, 0006379=mRNA cleavage, 0006364=rRNA processing" "0030677=ribonuclease P complex, 0005655=nucleolar ribonuclease P complex, 0000172=ribonuclease MRP complex" "BcDNA:LD45688, anon-WO0172774.38" "IPR002730=Ribonuclease P/MRP, subunit p29, IPR023534=Rof/RNase P-like, IPR016848=Ribonuclease P/MRP, p29 subunit" CG8038 16-Dec-15 2015_12 ENSDARG00000003263(pop4) WBGene00007603(C15C6.4) ENSXETG00000017598(POP4) ENSMUSG00000030423(Pop4) ENSG00000105171(POP4) "viable,visible" trichogen cell FBgn0020433 GMR Glass Multimer Reporter http://flybase.net/reports/FBgn0020433.html engineered_region glass multiple reporter 16-Dec-15 2015_12 FBgn0278601 Hsap\ARRB2::Zzzz\NIa http://flybase.net/reports/FBgn0278601.html engineered_fusion_gene ARRB2::Zzzz\NIa 16-Dec-15 2015_12 FBgn0259612 B0891 http://flybase.net/reports/FBgn0259612.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing vein L3,wing" FBgn0025467 tin::Mmus\Nkx2-5 Nkx2-5 http://flybase.net/reports/FBgn0025467.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0016635 E(gl)3C Enhancer of glass 3C http://flybase.net/reports/FBgn0016635.html gene 16-Dec-15 2015_12 rhabdomere FBgn0035753 RpL18 Ribosomal protein L18 http://flybase.net/reports/FBgn0035753.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "Rp L18, RpL18e, CG8615" "IPR021132=Ribosomal protein L18e, conserved site, IPR000039=Ribosomal protein L18e, IPR021131=Ribosomal protein L18e/L15P" CG8615 16-Dec-15 2015_12 ENSDARG00000029533(zgc:92872) "YNL301C(RPL18B),YOL120C(RPL18A)" WBGene00004430(rpl-18) ENSXETG00000003164(rpl18) ENSMUSG00000059070(Rpl18) ENSG00000063177(RPL18) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC22323 IEK 5.591919198 -0.823850362 4.872171069 -5.390907854 2.780343758 4.103543711 FBgn0031955 CG14535 http://flybase.net/reports/FBgn0031955.html protein_coding_gene "0005524=ATP binding, 0008017=microtubule binding, 0016887=ATPase activity, 0003777=microtubule motor activity" "0007018=microtubule-based movement, 0048812=neuron projection morphogenesis" 0005871=kinesin complex "KIF26A/B, KIF26, DmKIF26, Kinesin Superfamily Protein 26" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001752=Kinesin motor domain, IPR027640=Kinesin-like protein" CG14535 16-Dec-15 2015_12 "ENSDARG00000024575(si:dkeyp-8f4.3),ENSDARG00000013343,ENSDARG00000069436,ENSDARG00000015016,ENSDARG00000042368(si:dkey-31d8.1)" ENSG00000066735(KIF26A) FBgn0263575 mir-4912 mir-4912 stem loop http://flybase.net/reports/FBgn0263575.html miRNA_gene "CR43560, dme-mir-4912" CR43560 16-Dec-15 2015_12 FBgn0011076 l(1)Q30 lethal (1) Q30 http://flybase.net/reports/FBgn0011076.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0265016 S1364-03 http://flybase.net/reports/FBgn0265016.html gene 16-Dec-15 2015_12 FBgn0267277 CR45713 http://flybase.net/reports/FBgn0267277.html non_protein_coding_gene CR45713 16-Dec-15 2015_12 FBgn0050466 CG30466 http://flybase.net/reports/FBgn0050466.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO19 IPR001810=F-box domain CG30466 16-Dec-15 2015_12 FBgn0044812 TotC Turandot C http://flybase.net/reports/FBgn0044812.html FBgn0051508 protein_coding_gene "0034605=cellular response to heat, 0009617=response to bacterium, 0034644=cellular response to UV" "0005615=extracellular space, 0005576=extracellular region" "Turandot C, tot, TOTc, CG31508, turandot C, Stress-inducible humoral factor Turandot C, totC, Turandot" IPR010825=Stress-inducible humoral factor Turandot CG31508 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0011603 ine inebriated http://flybase.net/reports/FBgn0011603.html FBgn0020253 protein_coding_gene "0009881=photoreceptor activity, 0005034=osmosensor activity, 0005328=neurotransmitter:sodium symporter activity" "0042066=perineurial glial growth, 0009414=response to water deprivation, 0006836=neurotransmitter transport, 0019226=transmission of nerve impulse, 0050891=multicellular organismal water homeostasis, 0047484=regulation of response to osmotic stress" "0016323=basolateral plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "CG15444, ine/rosA, rosA, DMINE, CG15444d" "IPR000175=Sodium:neurotransmitter symporter, IPR002944=Sodium:neurotransmitter symporter, inebriated" CG15444 16-Dec-15 2015_12 "ENSDARG00000046091(LOC569007),ENSDARG00000002405(si:ch211-225b11.1)" " embryonic stage | stage >=13 , embryonic stage | stage >8 , embryonic stage | late , adult stage , embryonic stage | cellular blastoderm " " embryonic/larval midgut

, head | restricted

, inclusive hindgut primordium

, Malpighian tubule

, garland cell

, tracheal pit

, embryonic/larval foregut

,

ubiquitous , embryonic nervous system

, ventral nervous system | segmentally repeated

, pharyngeal muscle

, anal plate

" "viable,fertile,chemical sensitive,wild-type,behavior defective,paralytic,heat sensitive" FBgn0266196 CR44891 http://flybase.net/reports/FBgn0266196.html non_protein_coding_gene CR44891 16-Dec-15 2015_12 FBgn0022331 fs(3)167 fs(3)167 http://flybase.net/reports/FBgn0022331.html gene fs167 16-Dec-15 2015_12 FBgn0034945 CG10904 http://flybase.net/reports/FBgn0034945.html protein_coding_gene IPR006578=MADF domain CG10904 16-Dec-15 2015_12 viable FBgn0030370 Uch-L5R Uch-L5-related http://flybase.net/reports/FBgn0030370.html protein_coding_gene "0008242=omega peptidase activity, 0004843=ubiquitin-specific protease activity" "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" 0005838=proteasome regulatory particle "CG1950, Uch37R" "IPR017390=Ubiquitinyl hydrolase, UCH37 type, IPR001578=Peptidase C12, ubiquitin carboxyl-terminal hydrolase" CG1950 16-Dec-15 2015_12 ENSDARG00000042635(uchl5) WBGene00006724(ubh-4) ENSXETG00000017223(UCHL5) ENSG00000116750(UCHL5) FBgn0013716 l(3)neo44 lethal (3) neo44 http://flybase.net/reports/FBgn0013716.html FBgn0020266 gene neo44 16-Dec-15 2015_12 "lethal,recessive" FBgn0010151 l(3)R115 lethal of Roberts 115 http://flybase.net/reports/FBgn0010151.html gene l(3)B115 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027611 LManII Lysosomal ë±-mannosidase II http://flybase.net/reports/FBgn0027611.html protein_coding_gene "0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, 0004559=alpha-mannosidase activity, 0008270=zinc ion binding, 0030246=carbohydrate binding" 0006013=mannose metabolic process "0005764=lysosome, 0005576=extracellular region" "lysosomal mannosidase, CG6206, lysosomal alpha-mannosidase II, class II lysosomal alpha-mannosidase, lysosomal alpha-mannosidase, LM, dLM408, LManII, Lysosomal alpha-mannosidase, LM408, dLM, BcDNA:GH02419" "IPR011013=Galactose mutarotase-like domain, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR015341=Glycoside hydrolase, family 38, central domain, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR000602=Glycoside hydrolase family 38, N-terminal domain" CG6206 16-Dec-15 2015_12 ENSDARG00000001897(zgc:110815) WBGene00018877(aman-1) ENSXETG00000011609(MAN2B2) ENSMUSG00000005142(Man2b1) ENSG00000104774(MAN2B1) viable FBgn0004021 wp warped http://flybase.net/reports/FBgn0004021.html gene 16-Dec-15 2015_12 "viable,recessive,male sterile,visible,dominant" FBgn0052601 ë_NACtes3 http://flybase.net/reports/FBgn0052601.html FBgn0030565 protein_coding_gene "CG9404, CG32601" IPR002715=Nascent polypeptide-associated complex NAC domain CG32601 16-Dec-15 2015_12 FBgn0065236 l(2)SH2165 lethal (2) SH2165 http://flybase.net/reports/FBgn0065236.html gene l(2)SH2 2165 16-Dec-15 2015_12 "lethal,recessive" FBgn0060485 l(3)S110610 lethal (3) S110610 http://flybase.net/reports/FBgn0060485.html gene 1106/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0024674 l(2)k00503 lethal (2) k00503 http://flybase.net/reports/FBgn0024674.html gene 3-May 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0052644 Mur11Da Mucin related 11Da http://flybase.net/reports/FBgn0052644.html protein_coding_gene 0005201=extracellular matrix structural constituent 0007304=chorion-containing eggshell formation "0031012=extracellular matrix, 0042600=chorion" "Mur11Da, CG32644" CG32644 16-Dec-15 2015_12 FBgn0016672 Ipp Inositol polyphosphate 1-phosphatase http://flybase.net/reports/FBgn0016672.html "FBgn0024890, FBgn0066012" protein_coding_gene "0004441=inositol-1,4-bisphosphate 1-phosphatase activity" "0046855=inositol phosphate dephosphorylation, 0046854=phosphatidylinositol phosphorylation, 0007268=synaptic transmission" "ipp, inositol polyphosphate 1-phosphatase, CG3028, anon-WO02059370.48" "IPR020550=Inositol monophosphatase, conserved site, IPR000760=Inositol monophosphatase" CG3028 16-Dec-15 2015_12 ENSDARG00000002897(LOC555899) ENSXETG00000015248(INPP1) ENSMUSG00000026102(Inpp1) ENSG00000151689(INPP1) " adult stage , embryonic stage -- adult stage " " head

, retina

,

ubiquitous " "hyperactive,neurophysiology defective,viable" synapse FBgn0264996 CR44147 http://flybase.net/reports/FBgn0264996.html non_protein_coding_gene CR44147 16-Dec-15 2015_12 FBgn0044121 E(rst)B6 E(rst)B6 http://flybase.net/reports/FBgn0044121.html gene 0001745=compound eye morphogenesis B6 16-Dec-15 2015_12 viable eye FBgn0085283 CG34254 http://flybase.net/reports/FBgn0085283.html protein_coding_gene IPR013320=Concanavalin A-like lectin/glucanase domain CG34254 16-Dec-15 2015_12 FBgn0015388 flx female lethal on X http://flybase.net/reports/FBgn0015388.html gene 16-Dec-15 2015_12 FBgn0037554 DNApol-ë_ DNApol-ë_ http://flybase.net/reports/FBgn0037554.html protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0003684=damaged DNA binding" 0019985=translesion synthesis "DNApol-iota, drad30B, CG7602, Poliota, DNA Pol II-iota, DNApol-i, DNA-pol iota, AAF54198, Dm-Poliota" "IPR001126=UmuC domain, IPR017961=DNA polymerase, Y-family, little finger domain" CG7602 16-Dec-15 2015_12 ENSDARG00000029250(zgc:110185) ENSMUSG00000038425(Poli) ENSG00000101751(POLI) viable FBgn0266324 CR44989 http://flybase.net/reports/FBgn0266324.html non_protein_coding_gene CR44989 16-Dec-15 2015_12 FBgn0002322 l(3)86Fa lethal (3) 86Fa http://flybase.net/reports/FBgn0002322.html gene l(3)ck1 16-Dec-15 2015_12 "lethal,body color defective" "wing,adult cuticle" FBgn0011324 l(3)j2B1 lethal (3) j2B1 http://flybase.net/reports/FBgn0011324.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031766 CG9117 http://flybase.net/reports/FBgn0031766.html protein_coding_gene IPR001279=Metallo-beta-lactamase CG9117 16-Dec-15 2015_12 WBGene00015388(C03F11.2) ENSMUSG00000049285(Mblac1) ENSG00000214309(MBLAC1) "viable,fertile" FBgn0005085 fs(2)OW809 female sterile (2) OW809 http://flybase.net/reports/FBgn0005085.html gene 16-Dec-15 2015_12 FBgn0040614 CG12882 http://flybase.net/reports/FBgn0040614.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027973 l(3)S141110 lethal (3) S141110 http://flybase.net/reports/FBgn0027973.html gene 1411/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0025832 Fen1 Flap endonuclease 1 http://flybase.net/reports/FBgn0025832.html protein_coding_gene "0004519=endonuclease activity, 0003677=DNA binding, 0048256=flap endonuclease activity" "0022008=neurogenesis, 0006281=DNA repair" 0005634=nucleus "fen1, CG8648, EG:EG0003.3, FEN1, flap endonuclease-1, DmFEN-1" "IPR006084=XPG/Rad2 endonuclease, IPR008918=Helix-hairpin-helix motif, class 2, IPR003583=Helix-hairpin-helix DNA-binding motif, class 1, IPR019974=XPG conserved site, IPR006086=XPG-I domain, IPR020045=5'-3' exonuclease, C-terminal domain, IPR006085=XPG N-terminal, IPR029060=PIN domain-like, IPR023426=Flap structure-specific endonuclease" CG8648 16-Dec-15 2015_12 ENSDARG00000011404 YKL113C(RAD27) WBGene00000794(crn-1) ENSXETG00000006703(FEN1) ENSMUSG00000024742(Fen1) ENSG00000168496(FEN1) "neuroanatomy defective,lethal,viable,visible" "neuroblast,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0035545 CG12607 http://flybase.net/reports/FBgn0035545.html FBgn0061392 protein_coding_gene BcDNA:RE67729 CG12607 16-Dec-15 2015_12 viable FBgn0065554 l(2)SH1017 lethal (2) SH1017 http://flybase.net/reports/FBgn0065554.html gene l(2)SH2 1017 16-Dec-15 2015_12 "lethal,recessive" FBgn0037340 CG14671 http://flybase.net/reports/FBgn0037340.html protein_coding_gene CG14671 16-Dec-15 2015_12 FBgn0039644 CG11897 http://flybase.net/reports/FBgn0039644.html protein_coding_gene "0015238=drug transmembrane transporter activity, 0005524=ATP binding, 0008559=xenobiotic-transporting ATPase activity" 0055085=transmembrane transport 0016021=integral component of membrane "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003439=ABC transporter-like, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR017871=ABC transporter, conserved site" CG11897 16-Dec-15 2015_12 viable DRSC26545 K 0.177360207 -0.207663781 -0.058802605 0.034238749 -0.691097197 2.061695079 FBgn0053922 CG33922 http://flybase.net/reports/FBgn0053922.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33922 16-Dec-15 2015_12 FBgn0033728 Cpr49Ae Cuticular protein 49Ae http://flybase.net/reports/FBgn0033728.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG8505, DmelCpr49Ae" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8505 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0004391 shtd shattered http://flybase.net/reports/FBgn0004391.html FBgn0030639 protein_coding_gene 0090302=APC-Cdc20 complex activity "0048749=compound eye development, 0022008=neurogenesis, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0007067=mitotic nuclear division" 0005680=anaphase-promoting complex "SHTD, Apc1, Shattered, APC1, Shtd, CG9198" IPR024990=Anaphase-promoting complex subunit 1 CG9198 16-Dec-15 2015_12 YNL172W(APC1) ENSXETG00000000782(ANAPC1) ENSMUSG00000014355(Anapc1) ENSG00000153107(ANAPC1) "lethal - all die before end of pupal stage,some die during pupal stage,visible,mitotic cell cycle defective,increased cell death,lethal,neuroanatomy defective,viable" "eye,photoreceptor cell,mitotic cell cycle,eye disc,ommatidium,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0085325 CG34296 http://flybase.net/reports/FBgn0085325.html protein_coding_gene CG34296 16-Dec-15 2015_12 FBgn0065897 l(2)SH0206 lethal (2) SH0206 http://flybase.net/reports/FBgn0065897.html gene l(2)SH2 0206 16-Dec-15 2015_12 "lethal,recessive" FBgn0266041 CR44806 http://flybase.net/reports/FBgn0266041.html non_protein_coding_gene CR44806 16-Dec-15 2015_12 FBgn0001419 l(1)6Dc lethal (1) 6Dc http://flybase.net/reports/FBgn0001419.html gene "l(1)EM25, l(1)EA42, EM25" 16-Dec-15 2015_12 "lethal,recessive" FBgn0060300 nullo::Dvir\nullo nullo http://flybase.net/reports/FBgn0060300.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0000134 Ars-region12 Autonomous replicating sequence region 12 http://flybase.net/reports/FBgn0000134.html region "Dm665, Ars12, Ars sequence 12" 16-Dec-15 2015_12 FBgn0029181 E(Khc)ek6 E(Khc)ek6 http://flybase.net/reports/FBgn0029181.html gene 16-Dec-15 2015_12 FBgn0024612 olf534 olfactory 534 http://flybase.net/reports/FBgn0024612.html gene 16-Dec-15 2015_12 FBgn0005530 l(2)52ACg lethal (2) 52ACg http://flybase.net/reports/FBgn0005530.html gene unnamed 16-Dec-15 2015_12 FBgn0029084 gom gomdanji http://flybase.net/reports/FBgn0029084.html FBgn0041572 protein_coding_gene 0005509=calcium ion binding "0007619=courtship behavior, 0019722=calcium-mediated signaling, 0007612=learning" CG6727 CG6727 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0002503 l(3)SG63 lethal (3) SG63 http://flybase.net/reports/FBgn0002503.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0038005 Cyp313a5 Cyp313a5 http://flybase.net/reports/FBgn0038005.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0005506=iron ion binding, 0020037=heme binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG15807, 313a5, CYP313a5" "IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450" CG15807 16-Dec-15 2015_12 YDR402C(DIT2) viable FBgn0002870 mu mussed http://flybase.net/reports/FBgn0002870.html gene 16-Dec-15 2015_12 visible "adult thorax,dorsal,wing" FBgn0035626 lin-28 lin-28 http://flybase.net/reports/FBgn0035626.html FBgn0063073 protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" "0048477=oogenesis, 0006355=regulation of transcription, DNA-templated, 2000632=negative regulation of pre-miRNA processing" "CG17334, BcDNA:RE05342, EP(3)0915, lin28" "IPR012340=Nucleic acid-binding, OB-fold, IPR011129=Cold shock protein, IPR001878=Zinc finger, CCHC-type, IPR002059=Cold-shock protein, DNA-binding" CG17334 16-Dec-15 2015_12 "ENSDARG00000052511,ENSDARG00000004328(LOC799825),ENSDARG00000016999(lin28a)" WBGene00003014(lin-28) "ENSXETG00000012324(lin28),ENSXETG00000013293(LIN28B)" "ENSMUSG00000050966,ENSMUSG00000063804(Lin28b)" "ENSG00000187772(LIN28B),ENSG00000131914(LIN28A)" embryonic stage " embryonic stage , larval stage | first instar , pupal stage " DRSC10261 EK -0.863058748 -1.142396815 -2.337710006 0.94765551 2.245989086 1.911352244 FBgn0035173 CG13907 http://flybase.net/reports/FBgn0035173.html protein_coding_gene 0015355=secondary active monocarboxylate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG13907 16-Dec-15 2015_12 ENSDARG00000042807(zgc:158390) "YNL125C(ESBP6),YKL221W(MCH2)" WBGene00003986(pes-22) ENSXETG00000005121(SLC16A9) ENSMUSG00000026220(Slc16a14) ENSG00000163053(SLC16A14) FBgn0259997 CG41073 http://flybase.net/reports/FBgn0259997.html "FBgn0069950, FBgn0046676" protein_coding_gene "38C.19, anon-38C.19, CG40171" 16-Dec-15 2015_12 FBgn0034946 CG3065 http://flybase.net/reports/FBgn0034946.html protein_coding_gene "0046872=metal ion binding, 0043565=sequence-specific DNA binding" 0006357=regulation of transcription from RNA polymerase II promoter 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG3065 16-Dec-15 2015_12 "YPL230W(USV1),YMR182C(RGM1)" "viable,fertile" FBgn0026354 Su(SuRaf1)19-2 Su(SuRaf1)19-2 http://flybase.net/reports/FBgn0026354.html gene Su[Su(Raf)1]19-2 16-Dec-15 2015_12 "lethal,recessive" FBgn0001509 l(1)10Fc lethal (1) 10Fc http://flybase.net/reports/FBgn0001509.html gene 16-Dec-15 2015_12 lethal FBgn0038638 CG7702 http://flybase.net/reports/FBgn0038638.html protein_coding_gene "connectin-like, CT23351, 7702" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG7702 16-Dec-15 2015_12 "viable,fertile" FBgn0027564 CG3149 http://flybase.net/reports/FBgn0027564.html protein_coding_gene 0005319=lipid transporter activity 0006869=lipid transport 0016021=integral component of membrane BcDNA:GH08388 IPR007594=RFT1 CG3149 16-Dec-15 2015_12 ENSDARG00000060398(LOC559873) YBL020W(RFT1) WBGene00022677(ZK180.3) ENSMUSG00000052395(Rft1) ENSG00000163933(RFT1) FBgn0061141 l(3)S000624c lethal (3) S000624c http://flybase.net/reports/FBgn0061141.html gene 16-Dec-15 2015_12 lethal FBgn0000286 Cf2 Chorion factor 2 http://flybase.net/reports/FBgn0000286.html FBgn0062475 protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0046872=metal ion binding, 0043565=sequence-specific DNA binding, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0007527=adult somatic muscle development, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter" 0005634=nucleus "CG11924, cf2, Chorion factor-2, CF2, BcDNA:GM09668, chorion factor 2, Chorion Factor-2, CF2.5" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG11924 16-Dec-15 2015_12 "YPR015C(),YPR013C()" " oogenesis stage && adult stage | female , adult stage && oogenesis stage , adult stage | male , embryonic stage , spermatogenesis && adult stage , embryonic stage -- adult stage , pupal stage " " ovary

, follicle cell

, testis

, egg chamber

" adult stage && oogenesis stage follicle cell

"viable,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal,visible,flightless,jumping defective,flight defective" "indirect flight muscle,myosin filament,dorsal appendage,non-rescuable maternal effect,denticle belt,embryonic/first instar larval cuticle,egg chamber,follicle cell,trichogen cell,mesothoracic tergum,mesothoracic extracoxal depressor muscle 66,Z disc,M band" FBgn0263966 BG02395 http://flybase.net/reports/FBgn0263966.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0001428 stout strung out http://flybase.net/reports/FBgn0001428.html gene "jnL1, JNXL1, lethal(1)6Ee, l(1)jnL1, l(1)6Ee" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,visible,dominant" "hypostomal sclerite,dorsal bridge,mouth hooks,metathoracic ventral denticle belt,arista,wing,macrochaeta" FBgn0002409 l(3)99Dj lethal (3) 99Dj http://flybase.net/reports/FBgn0002409.html gene 16-Dec-15 2015_12 lethal FBgn0266504 s-332 http://flybase.net/reports/FBgn0266504.html gene 16-Dec-15 2015_12 FBgn0034844 CG9861 http://flybase.net/reports/FBgn0034844.html protein_coding_gene CG9861 16-Dec-15 2015_12 viable DRSC04576 E -0.352295782 0.217012298 3.690707226 -0.288847633 0.793603246 -0.814203882 FBgn0020055 E(wa)757 E(wa)757 http://flybase.net/reports/FBgn0020055.html gene E757 16-Dec-15 2015_12 eye color defective pigment cell FBgn0263625 CR43634 http://flybase.net/reports/FBgn0263625.html non_protein_coding_gene lincRNA.851 CR43634 16-Dec-15 2015_12 FBgn0086409 dbb doublebubble http://flybase.net/reports/FBgn0086409.html gene 16-Dec-15 2015_12 FBgn0035695 CG10226 http://flybase.net/reports/FBgn0035695.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0042623=ATPase activity, coupled, 0015238=drug transmembrane transporter activity, 0005524=ATP binding" "0055085=transmembrane transport, 0031427=response to methotrexate, 0015893=drug transport" "0016021=integral component of membrane, 0005886=plasma membrane" "ABC multidrug transporter, AMT" "IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10226 16-Dec-15 2015_12 YKL209C(STE6) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051038 CG31038 http://flybase.net/reports/FBgn0051038.html "FBgn0039716, FBgn0039717" protein_coding_gene "CG15512, CG7854" CG31038 16-Dec-15 2015_12 "viable,fertile" FBgn0040743 CG15919 http://flybase.net/reports/FBgn0040743.html protein_coding_gene CG15919 16-Dec-15 2015_12 viable FBgn0027513 ana2 anastral spindle 2 http://flybase.net/reports/FBgn0027513.html protein_coding_gene "0000132=establishment of mitotic spindle orientation, 0007099=centriole replication, 0055059=asymmetric neuroblast division, 0051298=centrosome duplication, 0007052=mitotic spindle organization, 0010457=centriole-centriole cohesion, 0034454=microtubule anchoring at centrosome" "0005814=centriole, 0005813=centrosome" "BcDNA:LD22033, Ana-2, Ana2, CG8262, anastral spindle phenotype 2" CG8262 16-Dec-15 2015_12 "neuroanatomy defective,meiotic cell cycle defective,viable" "embryonic/larval neuroblast,supernumerary,mushroom body neuroblast,astral microtubule,type I neuroblast,somatic clone,type II neuroblast,secondary neuroblast,centriolemat.ë±Tub67C.THsimVP16,centriole,spermatocyte" FBgn0065191 l(2)SH2329 lethal (2) SH2329 http://flybase.net/reports/FBgn0065191.html gene l(2)SH2 2329 16-Dec-15 2015_12 "lethal,recessive" FBgn0005533 RpS17 Ribosomal protein S17 http://flybase.net/reports/FBgn0005533.html "FBgn0002217, FBgn0002615, FBgn0025290, FBgn0064883" protein_coding_gene 0003735=structural constituent of ribosome "0006414=translational elongation, 0006412=translation, 0000028=ribosomal small subunit assembly" "0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "D9, unnamed, rpS17, M(3)i(55), M(3L)i, Rp S17, BcDNA:RE44119, l(3)dtOA4, M(3)67C, Minute(3)67C, ribosomal protein S17, M(3)RpS17, CG3922, RPS17, l(3)67BDo, Rps17, anon-EST:Posey48, M(3)67, M, M(3)q, M(3L)i[55], RS17_DROME, M(3)S33, Minute, M(3)i[55], M(3)i" "IPR018273=Ribosomal protein S17e, conserved site, IPR001210=Ribosomal protein S17e" CG3922 16-Dec-15 2015_12 ENSDARG00000035756(zgc:77702) "YML024W(RPS17A),YDR447C(RPS17B)" WBGene00004486(rps-17) ENSXETG00000010656() "ENSMUSG00000061787(Rps17),ENSMUSG00000050978(Gm5215)" "ENSG00000182774(RPS17L),ENSG00000184779(RPS17),ENSG00000060303,ENSG00000197575" "Minute,developmental rate defective,partially lethal - majority live,female sterile,dominant,visible,lethal,recessive,cell lethalcell lethal,somatic clone,size defective" "macrochaeta,adult heart" DRSC11271 EK -0.391006664 -1.21262834 1.241025078 -3.162834602 -0.87455409 2.752812484 FBgn0262971 CR43282 http://flybase.net/reports/FBgn0262971.html non_protein_coding_gene hpRNA1 CR43282 16-Dec-15 2015_12 FBgn0085273 CG34244 http://flybase.net/reports/FBgn0085273.html protein_coding_gene IPR002350=Kazal domain CG34244 16-Dec-15 2015_12 FBgn0262360 CG43058 http://flybase.net/reports/FBgn0262360.html protein_coding_gene 0008270=zinc ion binding "IPR001841=Zinc finger, RING-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG43058 16-Dec-15 2015_12 FBgn0085731 CG42229 http://flybase.net/reports/FBgn0085731.html FBan0041436 protein_coding_gene 16-Dec-15 2015_12 FBgn0011933 tRNA:N5:42Ac transfer RNA:asn5:42Ac http://flybase.net/reports/FBgn0011933.html "FBgn0003759, FBgn0050307, FBgn0050518, FBgn0060132" tRNA_gene "0033442=AAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:N:GTT:AE002769-b, tRNA:asn5:42Ac, chr2R.trna97-AsnGTT, AE002769.trna6-AsnGTT, CR30307, asn-tRNA, CR30518" CR30518 16-Dec-15 2015_12 FBgn0051106 CG31106 http://flybase.net/reports/FBgn0051106.html FBgn0039292 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane CG13655 "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG31106 16-Dec-15 2015_12 viable FBgn0082590 l(2)NC309 lethal (2) NC309 http://flybase.net/reports/FBgn0082590.html gene NC309 16-Dec-15 2015_12 FBgn0266108 mei-86 meiotic 86 http://flybase.net/reports/FBgn0266108.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female" FBgn0005679 mcd2 muscle cell death 2 http://flybase.net/reports/FBgn0005679.html gene mcd-2 16-Dec-15 2015_12 "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "muscle 18a,maternal effect,muscle 18b" FBgn0262142 CR42868 http://flybase.net/reports/FBgn0262142.html non_protein_coding_gene CG42868 CR42868 16-Dec-15 2015_12 FBgn0060945 l(3)S038305 lethal (3) S038305 http://flybase.net/reports/FBgn0060945.html gene 0383/05 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" FBgn0001356 l(1)1EFe lethal (1) 1EFe http://flybase.net/reports/FBgn0001356.html gene l(1)BA5 16-Dec-15 2015_12 lethal FBgn0030832 CG10597 http://flybase.net/reports/FBgn0030832.html protein_coding_gene CG10597 16-Dec-15 2015_12 viable FBgn0050480 CG30480 http://flybase.net/reports/FBgn0050480.html FBgn0033956 protein_coding_gene CG18373 CG30480 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0040796 CG13064 http://flybase.net/reports/FBgn0040796.html protein_coding_gene CG13064 16-Dec-15 2015_12 FBgn0065264 l(2)SH2077 lethal (2) SH2077 http://flybase.net/reports/FBgn0065264.html gene l(2)SH2 2077 16-Dec-15 2015_12 "lethal,recessive" FBgn0034323 CG18537 http://flybase.net/reports/FBgn0034323.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG18537 16-Dec-15 2015_12 viable FBgn0266887 CR45348 http://flybase.net/reports/FBgn0266887.html non_protein_coding_gene CR45348 16-Dec-15 2015_12 FBgn0002435 l(3)KX305 lethal (3) KX305 http://flybase.net/reports/FBgn0002435.html gene 16-Dec-15 2015_12 lethal FBgn0002143 l(2)K333 lethal (2) K333 http://flybase.net/reports/FBgn0002143.html gene 16-Dec-15 2015_12 lethal FBgn0262422 mir-1011 mir-1011 stem loop http://flybase.net/reports/FBgn0262422.html "FBgn0250807, FBgn0262267" miRNA_gene "CR42974, miR-1011, dme-mir-1011" CR42974 16-Dec-15 2015_12 viable FBgn0030208 PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein http://flybase.net/reports/FBgn0030208.html FBgn0029505 protein_coding_gene 0019888=protein phosphatase regulator activity "0000278=mitotic cell cycle, 0022008=neurogenesis, 0035304=regulation of protein dephosphorylation" "0030289=protein phosphatase 4 complex, 0000775=chromosome, centromeric region" "Ppp4R2, BcDNA:LD29930, PP4R2, PP4 regulatory subunit, CG2890, PP4R, R2, PP4, PPP4R2, PP4R2r, protein phosphatase 4 regulatory subunit 2-related protein" IPR015267=Protein phosphatase 4 core regulatory subunit R2 CG2890 16-Dec-15 2015_12 "ENSDARG00000026540(ppp4r2a),ENSDARG00000053447(ppp4r2b)" WBGene00017064(ppfr-2) ENSXETG00000015932(ppp4r2) ENSMUSG00000052144(Ppp4r2) ENSG00000163605(PPP4R2) "decreased cell number,lethal,neuroanatomy defective,viable" "neuroblast,ganglion mother cell" FBgn0261349 Mst36Fb Male-specific transcript 36Fb http://flybase.net/reports/FBgn0261349.html "FBan0031791, FBgn0086682" protein_coding_gene 0007283=spermatogenesis "CG15165, mst36Fb, Mst36Fb, Male-specific transcript 36Fb, CG31791, CG42626" CG42626 16-Dec-15 2015_12 "male semi-fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0032354 CG4788 http://flybase.net/reports/FBgn0032354.html protein_coding_gene CG4788 16-Dec-15 2015_12 viable FBgn0040214 fs(?)BL54 fs(?)BL54 http://flybase.net/reports/FBgn0040214.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0266878 CR45339 http://flybase.net/reports/FBgn0266878.html non_protein_coding_gene CR45339 16-Dec-15 2015_12 FBgn0000214 brc brachymacrochaetae http://flybase.net/reports/FBgn0000214.html gene 0048477=oogenesis "C93, DCE-12, l(1)1Db" 16-Dec-15 2015_12 "lethal,recessive,visible,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,polyphasic" "macrochaeta & thorax,dorsocentral bristle,scutellar bristle,mesothoracic bristle,macrochaeta" FBgn0039873 Smvt Sodium-dependent multivitamin transporter http://flybase.net/reports/FBgn0039873.html protein_coding_gene 0008523=sodium-dependent multivitamin transmembrane transporter activity 0055085=transmembrane transport 0016020=membrane "CG2191, SMVT, sodium-dependent multivitamin transporter, smvt, dSLC5A5" "IPR001734=Sodium/solute symporter, IPR019900=Sodium/solute symporter, subgroup" CG2191 16-Dec-15 2015_12 YHL016C(DUR3) "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" trichogen cell FBgn0003061 anon-Pen57BC anon-Pen57BC http://flybase.net/reports/FBgn0003061.html gene "pen57BC, Pen57BC, GCR-27, GCR27" 16-Dec-15 2015_12 FBgn0032763 CG17568 http://flybase.net/reports/FBgn0032763.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG17568 16-Dec-15 2015_12 "viable,fertile" FBgn0022141 l(2)k06204 lethal (2) k06204 http://flybase.net/reports/FBgn0022141.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085644 CR41423 http://flybase.net/reports/FBgn0085644.html FBan0041423 pseudogene_attribute 0008234=cysteine-type peptidase activity 0006508=proteolysis CG41423 "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CR41423 16-Dec-15 2015_12 ENSXETG00000003609(senp6) ENSMUSG00000052917(Senp7) ENSG00000112701(SENP6) FBgn0034504 CG8929 http://flybase.net/reports/FBgn0034504.html FBgn0061527 protein_coding_gene anon-WO0118547.91 "IPR022137=Protein of unknown function DUF3669, zinc finger protein" CG8929 16-Dec-15 2015_12 viable DRSC22847 EK -0.210513875 0.589169143 0.365611414 2.143688128 -0.38535577 -1.541576429 FBgn0027586 CG5867 http://flybase.net/reports/FBgn0027586.html protein_coding_gene 0005615=extracellular space "BcDNA:GH05536, CT18390" IPR010562=Haemolymph juvenile hormone binding CG5867 16-Dec-15 2015_12 viable FBgn0035607 CG4835 http://flybase.net/reports/FBgn0035607.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG4835 16-Dec-15 2015_12 viable FBgn0028551 3Cy(2)2 3Cy(2)2 http://flybase.net/reports/FBgn0028551.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0029853 CG3781 http://flybase.net/reports/FBgn0029853.html protein_coding_gene "0008242=omega peptidase activity, 0004843=ubiquitin-specific protease activity" 0016579=protein deubiquitination Q9W422 IPR006155=Machado-Joseph disease protein MJD CG3781 16-Dec-15 2015_12 "ENSDARG00000057626(josd2),ENSDARG00000071548(josd1)" WBGene00022190(Y71H2AR.3) "ENSXETG00000002767(TEgg022o05.1),ENSXETG00000006895(JOSD1)" "ENSMUSG00000038695(Josd2),ENSMUSG00000022426(Josd1)" "ENSG00000161677(JOSD2),ENSG00000100221(JOSD1)" "viable,locomotor behavior defective" FBgn0032024 CG14273 http://flybase.net/reports/FBgn0032024.html protein_coding_gene CG14273 16-Dec-15 2015_12 DRSC02377 E 1.246913382 1.435130563 1.758280927 0.158196672 -0.177995774 0.438144834 FBgn0061004 l(3)S026438 lethal (3) S026438 http://flybase.net/reports/FBgn0061004.html gene 0264/38 16-Dec-15 2015_12 "lethal,recessive" FBgn0036518 RhoGAP71E Rho GTPase activating protein at 71E http://flybase.net/reports/FBgn0036518.html "FBgn0011793, FBgn0036517, FBgn0047223" protein_coding_gene 0005096=GTPase activator activity "0007480=imaginal disc-derived leg morphogenesis, 0007266=Rho protein signal transduction" "CG7396, CG16980, CG32149, RhoGAP-71E1, RhoGAP71E, BcDNA:LD07615, l(3)j6B9, RhoGap71E" "IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG32149 16-Dec-15 2015_12 "lethal,recessive,neuroanatomy defective,somatic clone,viable" "mushroom body & neuron | somatic clone,adult mushroom body,somatic clone" DRSC10232 I 1.040665398 2.675912947 0.699027824 1.151873403 0.225028776 0.017226112 FBgn0085113 S53.1 S53.1 http://flybase.net/reports/FBgn0085113.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0035034 CG3565 http://flybase.net/reports/FBgn0035034.html FBgn0044701 protein_coding_gene 0005509=calcium ion binding anon-WO0140519.176 "IPR028846=Recoverin family, IPR011992=EF-hand domain pair" CG3565 16-Dec-15 2015_12 "viable,fertile" FBgn0027637 ms(1)10 male sterile (1) 10 http://flybase.net/reports/FBgn0027637.html gene 16-Dec-15 2015_12 "male sterile,female fertile" FBgn0013575 l(3)82Fc lethal (3) 82Fc http://flybase.net/reports/FBgn0013575.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038083 CG5999 http://flybase.net/reports/FBgn0038083.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG5999 16-Dec-15 2015_12 "WBGene00007073(ugt-2),WBGene00007072(ugt-1),WBGene00013903(ugt-3),WBGene00020592(ugt-12),WBGene00020594(ugt-10),WBGene00020593(ugt-11),WBGene00020587(ugt-9),WBGene00019234(ugt-8),WBGene00019232(ugt-13),WBGene00019235(H23N18.4),WBGene00019233(ugt-14)" "lethal,viable" FBgn0085803 CR41550 http://flybase.net/reports/FBgn0085803.html FBan0041550 rRNA_gene CR41550 16-Dec-15 2015_12 FBgn0038644 CG7710 http://flybase.net/reports/FBgn0038644.html FBgn0063110 protein_coding_gene BcDNA:LP06586 16-Dec-15 2015_12 FBgn0031378 CG15362 http://flybase.net/reports/FBgn0031378.html protein_coding_gene 0003824=catalytic activity "IPR001310=Histidine triad (HIT) protein, IPR011146=HIT-like domain" CG15362 16-Dec-15 2015_12 ENSDARG00000055365(si:dkey-25e12.3) WBGene00016150(hint-3) ENSXETG00000027058(hint3) ENSG00000111911(HINT3) viable FBgn0043358 EP2409 EP2409 http://flybase.net/reports/FBgn0043358.html gene 16-Dec-15 2015_12 visible "scutellar bristle,ectopic,trichogen cell,tormogen cell" FBgn0033889 CG6701 http://flybase.net/reports/FBgn0033889.html FBgn0062680 protein_coding_gene 0046872=metal ion binding 0048813=dendrite morphogenesis "EP(2)2054, EP2054" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG6701 16-Dec-15 2015_12 YKL017C(HCS1) WBGene00016566(eri-7) "neuroanatomy defective,visible" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,eye,wing" DRSC07007 IE -1.873015639 -5.027359649 -2.312406222 -4.729090884 0.106441923 0.029536574 FBgn0263346 CG43427 http://flybase.net/reports/FBgn0263346.html "FBgn0051531, FBgn0037266, FBgn0037267, FBgn0051534, FBgn0037268, FBgn0037269, FBgn0044530" protein_coding_gene 0008270=zinc ion binding 0007476=imaginal disc-derived wing morphogenesis "CG31531, CG1054, CG1055, CG18253, anon-WO0140519.95, CG14653, CG31534" "IPR001781=Zinc finger, LIM-type" CG43427 16-Dec-15 2015_12 WBGene00017904(lim-8) FBgn0019848 anon-XVI anon-XVI http://flybase.net/reports/FBgn0019848.html gene XV1 16-Dec-15 2015_12 FBgn0036352 CG14110 http://flybase.net/reports/FBgn0036352.html protein_coding_gene CG14110 16-Dec-15 2015_12 viable DRSC10113 K -0.706882289 0.046051323 -0.680232552 0.53803833 5.79262649 0.24583953 FBgn0085695 CG41564 http://flybase.net/reports/FBgn0085695.html FBan0041564 protein_coding_gene 16-Dec-15 2015_12 FBgn0041715 teu teufel http://flybase.net/reports/FBgn0041715.html gene 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype,hyperplasia" "polytene chromosome,melanotic mass,embryonic/larval brain" FBgn0086391 BG02022 http://flybase.net/reports/FBgn0086391.html gene "0002121=inter-male aggressive behavior, 0042048=olfactory behavior" 16-Dec-15 2015_12 "viable,smell perception defective,behavior defective,recessive" FBgn0084698 Rst(2)Cyr Resistance 2 Cyromazine http://flybase.net/reports/FBgn0084698.html gene 16-Dec-15 2015_12 FBgn0001648 l(1)dn28 lethal (1) discs normal 28 http://flybase.net/reports/FBgn0001648.html gene l(1)d.norm.-28 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038032 CG10096 http://flybase.net/reports/FBgn0038032.html "FBgn0044571, FBgn0052919" protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "CG32919, anon-WO0140519.58" "IPR016040=NAD(P)-binding domain, IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding" CG10096 16-Dec-15 2015_12 "viable,fertile" FBgn0259986 nab nab http://flybase.net/reports/FBgn0259986.html "FBgn0065124, FBgn0053545, FBgn0016012, FBgn0035502, FBgn0035503, FBgn0069097" protein_coding_gene "0008134=transcription factor binding, 0003712=transcription cofactor activity" "0014019=neuroblast development, 0008283=cell proliferation, 0007626=locomotory behavior, 0048666=neuron development, 0035222=wing disc pattern formation, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "lethal (3) SH143, l(3)SH143, NAB, l(3)64Aj, CG33545, CG15000, CG15001, dNAB, l(2)SH3 143, l(3)SH21, dnab, Nab" "IPR006988=Nab, N-terminal, IPR006989=NAB co-repressor, domain" CG33545 16-Dec-15 2015_12 WBGene00003107(mab-10) "ENSXETG00000004428(NAB2),ENSXETG00000015250(NAB1)" DRSC08456 EK 0.631812525 -0.270517375 1.5351979 0.393439205 -0.763317914 -1.718326725 FBgn0262415 mir-289 mir-289 stem loop http://flybase.net/reports/FBgn0262415.html "FBgn0067703, FBgn0262255" miRNA_gene "mir-289, Dme-miR-289, miR-289, mir289, CR33605, CR42962, dme-miR-289-5p, dme-miR-289-3p" CR42962 16-Dec-15 2015_12 viable FBgn0002446 l(3)S4 lethal (3) S4 http://flybase.net/reports/FBgn0002446.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061147 l(3)S000108b lethal (3) S000108b http://flybase.net/reports/FBgn0061147.html gene 8-Jan 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0039818 CG11318 http://flybase.net/reports/FBgn0039818.html "FBgn0046607, FBgn0046608" protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.122, RE14222p, anon-WO0170980.121" "IPR000832=GPCR, family 2, secretin-like, IPR000203=GPS motif, IPR017981=GPCR, family 2-like" CG11318 16-Dec-15 2015_12 "ENSDARG00000041399,ENSDARG00000041404,ENSDARG00000056062,ENSDARG00000013653(zgc:63629),ENSDARG00000026313,ENSDARG00000069356(id:ibd2808),ENSDARG00000058809" "ENSMUSG00000031785(Gpr56),ENSMUSG00000061577(Gpr114),ENSMUSG00000031298(Gpr64),ENSMUSG00000060470(Gpr97)" ENSG00000144820(GPR128) "viable,fertile" FBgn0051121 CG31121 http://flybase.net/reports/FBgn0051121.html "FBgn0039242, FBgn0039243, FBgn0042211, FBgn0063237" protein_coding_gene "0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005524=ATP binding" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "CG11764, BcDNA:GH19411, CG18633, CG18655" "IPR013525=ABC-2 type transporter, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG31121 16-Dec-15 2015_12 "viable,fertile" DRSC15361 K -0.417248836 -0.133328267 -0.693617711 -0.267799597 1.609321427 0.456881759 FBgn0005058 fs(2)OW104 female sterile (2) OW104 http://flybase.net/reports/FBgn0005058.html gene 16-Dec-15 2015_12 FBgn0260811 EP3-1809 http://flybase.net/reports/FBgn0260811.html gene 16-Dec-15 2015_12 FBgn0085824 CR41618 http://flybase.net/reports/FBgn0085824.html FBan0041618 rRNA_gene CR41618 16-Dec-15 2015_12 FBgn0024207 ol1 oocyte localisation 1 http://flybase.net/reports/FBgn0024207.html gene 16-Dec-15 2015_12 FBgn0036116 CG7888 http://flybase.net/reports/FBgn0036116.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport "IPR013057=Amino acid transporter, transmembrane domain" CG7888 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "WBGene00012804(Y43F4B.7),WBGene00020837(T27A1.5)" viable embryonic/larval hemocyte | third instar larval stage FBgn0011581 Ms Myosuppressin http://flybase.net/reports/FBgn0011581.html "FBgn0013996, FBgn0039185" protein_coding_gene "0071855=neuropeptide receptor binding, 0005184=neuropeptide hormone activity" "0008344=adult locomotory behavior, 0060457=negative regulation of digestive system process, 0045822=negative regulation of heart contraction, 0007218=neuropeptide signaling pathway, 0010459=negative regulation of heart rate, 0045986=negative regulation of smooth muscle contraction" 0005615=extracellular space "Myosuppressin, Drome-MS, MEMS, dromyosuppressin, cg6440, myosuppressin, TDVDHVFLRFamide, MS, Drm-MS, dms, Dromyosuppressin, Drm-myosuppressin, DMS, Dm-MS, Dms, CG6440, Nems, Neomyosuppressin, FLRFa" CG6440 16-Dec-15 2015_12 "lethal,viable" FBgn0027865 Tsp96F Tetraspanin 96F http://flybase.net/reports/FBgn0027865.html protein_coding_gene "0016021=integral component of membrane, 0005886=plasma membrane" "LD19727, Dm.Tsp96F, CG6120, BcDNA:LD19727" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG6120 16-Dec-15 2015_12 WBGene00006634(tsp-8) "ENSMUSG00000027215(Cd82),ENSMUSG00000037706(Cd81),ENSMUSG00000030342(Cd9),ENSMUSG00000027858(Tspan2),ENSMUSG00000030798(Cd37)" "lethal,viable,fertile" FBgn0028220 l(3)S007608 lethal (3) S007608 http://flybase.net/reports/FBgn0028220.html gene 0076/08 16-Dec-15 2015_12 "viable,lethal,recessive" FBgn0020572 anon-62Ea anon-62Ea http://flybase.net/reports/FBgn0020572.html gene unnamed 16-Dec-15 2015_12 FBgn0000583 eql equatorial-less http://flybase.net/reports/FBgn0000583.html gene 16-Dec-15 2015_12 "lethal,recessive" "photoreceptor cell R1,somatic clone,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,ommatidium" FBgn0033968 hui hase und igel http://flybase.net/reports/FBgn0033968.html protein_coding_gene 0035220=wing disc development "hare and hedgehog, CG10200" CG10200 16-Dec-15 2015_12 "viable,visible,lethal" "trichogen cell,wing vein L3,wing vein L4,anterior crossvein,wing,posterior,wing margin bristle" FBgn0027572 CG5009 http://flybase.net/reports/FBgn0027572.html protein_coding_gene "0003995=acyl-CoA dehydrogenase activity, 0003997=acyl-CoA oxidase activity, 0050660=flavin adenine dinucleotide binding" "0006635=fatty acid beta-oxidation, 0006629=lipid metabolic process, 0006091=generation of precursor metabolites and energy, 0019395=fatty acid oxidation, 0006693=prostaglandin metabolic process" 0005777=peroxisome "GH07485, BcDNA:GH07485" "IPR012258=Acyl-CoA oxidase, IPR002655=Acyl-CoA oxidase, C-terminal, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR029320=Acyl-coenzyme A oxidase, N-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain" CG5009 16-Dec-15 2015_12 ENSDARG00000014727(acox1) "WBGene00010336(F59F4.1),WBGene00009104(F25C8.1),WBGene00008564(F08A8.1),WBGene00008567(F08A8.4),WBGene00008566(F08A8.3),WBGene00008565(F08A8.2),WBGene00008167(C48B4.1)" "ENSXETG00000012601(acox1),ENSXETG00000023676(acox2)" ENSMUSG00000020777(Acox1) ENSG00000161533(ACOX1) "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0035468 Gr63a Gustatory receptor 63a http://flybase.net/reports/FBgn0035468.html protein_coding_gene 0008527=taste receptor activity "0003031=detection of carbon dioxide, 0010037=response to carbon dioxide, 0008340=determination of adult lifespan, 0050909=sensory perception of taste" 0016021=integral component of membrane "Gustatory receptor 63F1, gr63a, Gr63F1, GR63a, CG14979, DmGr63a" IPR013604=7TM chemoreceptor CG14979 16-Dec-15 2015_12 "neurophysiology defective,recessive,chemosensitive behavior defective,long lived,female limited,oxidative stress response defective,female,smell perception defective" abdominal 1 desC neuron FBgn0060426 l(3)S126615a lethal (3) S126615a http://flybase.net/reports/FBgn0060426.html gene 1266/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0029137 Patsas Patsas http://flybase.net/reports/FBgn0029137.html FBgn0032410 protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005794=Golgi apparatus CG6618 "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG6618 16-Dec-15 2015_12 ENSXETG00000024508() "viable,body color defective" mesothoracic tergum FBgn0015437 l(1)5AEa lethal (1) 5AEa http://flybase.net/reports/FBgn0015437.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000859 fs(1)M53 female sterile (1) M53 http://flybase.net/reports/FBgn0000859.html gene 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0265494 BG01888 http://flybase.net/reports/FBgn0265494.html gene 16-Dec-15 2015_12 FBgn0034223 Tes Testin ortholog http://flybase.net/reports/FBgn0034223.html protein_coding_gene 0008270=zinc ion binding "0015629=actin cytoskeleton, 0005737=cytoplasm" "CG6522, dTES" "IPR001781=Zinc finger, LIM-type, IPR010442=PET domain" CG6522 16-Dec-15 2015_12 ENSDARG00000051857(tes) WBGene00015217(tag-224) "ENSXETG00000011568(tes),ENSXETG00000015748(LMCD1)" "ENSMUSG00000068113(Gm4907),ENSMUSG00000029552(Tes),ENSMUSG00000082335(Gm4985),ENSMUSG00000057604(Lmcd1)" "ENSG00000071282(LMCD1),ENSG00000135269(TES)" viable FBgn0262738 norpA no receptor potential A http://flybase.net/reports/FBgn0262738.html "FBgn0004625, FBgn0002961, FBgn0004617, FBgn0027725, FBgn0086549" protein_coding_gene "0004435=phosphatidylinositol phospholipase C activity, 0004629=phospholipase C activity, 0005096=GTPase activator activity, 0005509=calcium ion binding" "0007608=sensory perception of smell, 0045494=photoreceptor cell maintenance, 0016056=rhodopsin mediated signaling pathway, 0006651=diacylglycerol biosynthetic process, 0051482=positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, 0035556=intracellular signal transduction, 0006644=phospholipid metabolic process, 0008344=adult locomotory behavior, 0043052=thermotaxis, 0008377=light-induced release of internally sequestered calcium ion, 0009649=entrainment of circadian clock, 0008654=phospholipid biosynthetic process, 0001580=detection of chemical stimulus involved in sensory perception of bitter taste, 0046488=phosphatidylinositol metabolic process, 0019722=calcium-mediated signaling, 2000370=positive regulation of clathrin-mediated endocytosis, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0007602=phototransduction, 0002385=mucosal immune response, 0043153=entrainment of circadian clock by photoperiod, 0016059=deactivation of rhodopsin mediated signaling" "0016027=inaD signaling complex, 0016028=rhabdomere" "phospholipase-C, nofC, PI-PLC, Norp A, No Receptor Potential A, phospholipase Cbeta, PLC, phospholipase C[[beta]], Phospholipase C-beta, no-receptor potential A, phospholipase C, phospholipase C-beta, MRE18, no receptor potential, CdkA, PLC-beta, x16, NORPA, DIP2, NorpA, CG3620, rof, no-receptor-potential A, anon-EST:Posey221, no-receptor-potential-A, x13, eye-specific PLC, x24, PLCbeta, unnamed, x12, mRNA-like ncRNA in embryogenesis 18, no receptor potentials A" "IPR001711=Phospholipase C, phosphatidylinositol-specific, Y domain, IPR016280=Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR001192=Phosphoinositide phospholipase C family, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR009535=Phospholipase C-beta, conserved site, IPR000008=C2 domain, IPR011992=EF-hand domain pair, IPR015359=Phosphoinositide-specific phospholipase C, EF-hand-like domain" CG3620 16-Dec-15 2015_12 WBGene00001177(egl-8) ENSMUSG00000039943(Plcb4) ENSG00000101333(PLCB4) " adult stage , larval stage , embryonic stage , embryonic stage -- adult stage " " adult thorax

, adult head

, photoreceptor cell

, adult abdomen

, optic lobe

, thoracico-abdominal ganglion

, adult brain

" " adult stage , adult stage | female " " eye

, adult brain

, leg

, thoracico-abdominal ganglion

, retina

, ocellus

, adult head

, adult abdomen

, optic lobe

, adult thorax

" FBgn0265974 ttv tout-velu http://flybase.net/reports/FBgn0265974.html "FBgn0065697, FBgn0020245, FBgn0010469, FBgn0010592, FBgn0024670" protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0050509=N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, 0050508=glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, 0005515=protein binding, 0015020=glucuronosyltransferase activity" "0007224=smoothened signaling pathway, 0048488=synaptic vesicle endocytosis, 0008589=regulation of smoothened signaling pathway, 0008101=decapentaplegic signaling pathway, 0006024=glycosaminoglycan biosynthetic process, 0006044=N-acetylglucosamine metabolic process, 0015014=heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, 0048312=intracellular distribution of mitochondria, 0016055=Wnt signaling pathway, 0015012=heparan sulfate proteoglycan biosynthetic process, 0050808=synapse organization, 0008354=germ cell migration, 0030210=heparin biosynthetic process, 0007411=axon guidance" "0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005794=Golgi apparatus" "DEXT1, Tout velu, tout-velo, dExt1, CG10117, toutvelu, Ttv, l(2)SH2 0631, lethal (2) SH0631, l(2)05282, P1.15, l(2)k03617, l(2)k00115, l(2)00681, Ext1, tout velu, l(2)SH0631" "IPR015338=Exostosin , C-terminal, IPR029044=Nucleotide-diphospho-sugar transferases, IPR004263=Exostosin-like" CG10117 16-Dec-15 2015_12 ENSDARG00000020373(ext1a) ENSXETG00000019136(ext1) ENSMUSG00000061731(Ext1) ENSG00000182197(EXT1) FBgn0031811 CG13982 http://flybase.net/reports/FBgn0031811.html protein_coding_gene CG13982 16-Dec-15 2015_12 FBgn0050066 CR30066 http://flybase.net/reports/FBgn0050066.html non_protein_coding_gene 16-Dec-15 2015_12 DRSC22956 K 0.268450314 -1.023921737 0.59246633 -0.028937031 -0.900892656 2.660786025 FBgn0031865 Nha1 Na+/H+ hydrogen antiporter 1 http://flybase.net/reports/FBgn0031865.html protein_coding_gene 0015385=sodium:proton antiporter activity "0003096=renal sodium ion transport, 0055085=transmembrane transport" "0005903=brush border, 0016021=integral component of membrane" "DmNHA1, nha1, CG10806, serine protease" IPR006153=Cation/H+ exchanger CG10806 16-Dec-15 2015_12 ENSDARG00000052700(LOC571064) "WBGene00009618(F41E7.2),WBGene00009617(F41E7.1),WBGene00010214(F57G8.5)" ENSXETG00000021321() "ENSMUSG00000037994(Nhedc2),ENSMUSG00000050150(Nhedc1)" "ENSG00000164038(SLC9B2),ENSG00000164037(SLC9B1),ENSG00000214329" "viable,fertile" adult Malpighian tubule FBgn0023396 Cbp86A Calmodulin-binding protein 86A http://flybase.net/reports/FBgn0023396.html gene 0005516=calmodulin binding Calbindin 16-Dec-15 2015_12 FBgn0004475 art aristatarsia http://flybase.net/reports/FBgn0004475.html gene 0007379=segment specification 16-Dec-15 2015_12 "visible,recessive" arista FBgn0040351 CG11638 http://flybase.net/reports/FBgn0040351.html FBgn0029553 protein_coding_gene 0005509=calcium ion binding EG:BACR7A4.12 "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG11638 16-Dec-15 2015_12 "ENSDARG00000019990(cabp1),ENSDARG00000033411(zgc:92680),ENSDARG00000052016(zgc:112300),ENSDARG00000052277,ENSDARG00000028485(zgc:109977),ENSDARG00000002576(zgc:73060),ENSDARG00000008866(si:ch73-56f16.1)" viable FBgn0000666 fli-385 flightless 385 http://flybase.net/reports/FBgn0000666.html gene 0007629=flight behavior 16-Dec-15 2015_12 flightless FBgn0001904 l(2)22Ae lethal (2) 22Ae http://flybase.net/reports/FBgn0001904.html gene "l(2)neh18, l(2)neh-18" 16-Dec-15 2015_12 lethal FBgn0028584 l(?)rK270 lethal (?) rK270 http://flybase.net/reports/FBgn0028584.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0029055 l(1)G0452 lethal (1) G0452 http://flybase.net/reports/FBgn0029055.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262187 mir-970 mir-970 stem loop http://flybase.net/reports/FBgn0262187.html miRNA_gene "miR-970, 970, dme-miR-970-3p, dme-miR-970, CR42894" CR42894 16-Dec-15 2015_12 "visible,viable" "wing,wing vein,ectopic" FBgn0003489 sprd spread http://flybase.net/reports/FBgn0003489.html "FBgn0011352, FBgn0011501" gene "l(3)rJ407, l(3)j3C3, sd" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die,visible" wing FBgn0005552 l(3)85Fe lethal (3) 85Fe http://flybase.net/reports/FBgn0005552.html gene 16-Dec-15 2015_12 lethal FBgn0039887 CG2053 http://flybase.net/reports/FBgn0039887.html protein_coding_gene "IPR007216=Rcd1/Caf40, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG2053 16-Dec-15 2015_12 viable FBgn0032839 CG10659 http://flybase.net/reports/FBgn0032839.html protein_coding_gene 0008080=N-acetyltransferase activity "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG10659 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0051472 sgll sugarlethal http://flybase.net/reports/FBgn0051472.html FBgn0037522 protein_coding_gene "0010181=FMN binding, 0004733=pyridoxamine-phosphate oxidase activity" "0042823=pyridoxal phosphate biosynthetic process, 0055114=oxidation-reduction process, 0009744=response to sucrose, 0042816=vitamin B6 metabolic process, 0008615=pyridoxine biosynthetic process" "CG31472, dPNPO, CG2649, pyridoxine 5'-phosphate oxidase" "IPR011576=Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, IPR000659=Pyridoxamine 5'-phosphate oxidase, IPR019740=Pyridoxamine 5'-phosphate oxidase, conserved site, IPR019576=Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal, IPR012349=FMN-binding split barrel" CG31472 16-Dec-15 2015_12 ENSDARG00000017612(pnpo) YBR035C(PDX3) WBGene00018996(F57B9.1) ENSXETG00000021955(PNPO) ENSMUSG00000018659(Pnpo) ENSG00000108439(PNPO) "short lived,nutrition conditional,chemical sensitive,partially lethal - majority die" FBgn0016682 Mrp53 Mrp53 http://flybase.net/reports/FBgn0016682.html gene 0003697=single-stranded DNA binding 0005737=cytoplasm mrp53 16-Dec-15 2015_12 FBgn0020845 l(2)122 lethal (2) 122 http://flybase.net/reports/FBgn0020845.html gene T(2;3)Hin122 16-Dec-15 2015_12 lethal FBgn0004613 Walker Walker http://flybase.net/reports/FBgn0004613.html gene Wk 16-Dec-15 2015_12 "visible,conditional,lethal,recessive,dominant" "wing,conditional,wing disc" FBgn0086224 Cdl-1 CID delocalization-1 http://flybase.net/reports/FBgn0086224.html gene "0000775=chromosome, centromeric region" CDL-1 16-Dec-15 2015_12 FBgn0005033 E(Pc)a Enhancer of Polycomb a http://flybase.net/reports/FBgn0005033.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant,homeotic" "mesothoracic leg,metathoracic leg,embryonic abdominal segment 1,embryonic abdominal segment 4" FBgn0005029 dta delta wing http://flybase.net/reports/FBgn0005029.html gene 16-Dec-15 2015_12 "visible,viable,female sterile,recessive" wing FBgn0264666 tiny-tubes tiny tubes http://flybase.net/reports/FBgn0264666.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0001123 Gë±s G protein ë± s subunit http://flybase.net/reports/FBgn0001123.html protein_coding_gene "0003924=GTPase activity, 0031683=G-protein beta/gamma-subunit complex binding, 0001664=G-protein coupled receptor binding, 0004871=signal transducer activity, 0005525=GTP binding" "0007611=learning or memory, 0022416=chaeta development, 0007476=imaginal disc-derived wing morphogenesis, 0010353=response to trehalose, 0035220=wing disc development, 0007268=synaptic transmission, 0007190=activation of adenylate cyclase activity, 0050916=sensory perception of sweet taste, 2000253=positive regulation of feeding behavior, 0007528=neuromuscular junction development, 0007632=visual behavior, 0007186=G-protein coupled receptor signaling pathway, 0007191=adenylate cyclase-activating dopamine receptor signaling pathway, 0048148=behavioral response to cocaine, 0002165=instar larval or pupal development" "0005604=basement membrane, 0005886=plasma membrane, 0031234=extrinsic component of cytoplasmic side of plasma membrane, 0005834=heterotrimeric G-protein complex" "GalphaS, G[[s]]alpha, G-5alpha, CG2835, Gsalpha, Galpha[[s]], dgsalpha, Gs, Gsalpha60A, Galpha[[s]]60A, Gs-alpha, DGs, GSalpha, G[[alphas]], G-salpha 60A, G-alpha-60A, Gs-alpha60A, Galphas, Galpha60A, G[[s]]-alpha-60A, G-salpha60A, G[[S]]alpha, G[[s]], dG[[alphas]], Gaalpha, dgs, G protein salpha 60A, G-alpha s, stimulatory alpha subunit of G protein, DGsalpha" "IPR000367=G-protein alpha subunit, group S, IPR011025=G protein alpha subunit, helical insertion, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit" CG2835 16-Dec-15 2015_12 "ENSDARG00000043094(gnas),ENSDARG00000045415(gnal)" WBGene00001745(gsa-1) ENSXETG00000019702(GNAL) "ENSMUSG00000024524(Gnal),ENSMUSG00000027523(Gnas)" ENSG00000141404(GNAL) " embryonic stage--pupal stage , adult stage " " adult brain cortex

, adult head

, eye

" " adult stage && oogenesis stage , adult stage , embryonic stage | stage >8 " " follicle cell

, neuropil adult brain

, adult antennal nerve | restricted

, neuropil thoracic ganglion

, adult brain cortex

, organism

" "lethal,recessive,taste perception defective,circadian rhythm defective,wild-type,viable,hypoactive,developmental rate defective,locomotor behavior defective,neurophysiology defective,behavior defective,immune response defective,decreased cell death,somatic clone,smell perception defective,visible,memory defective,increased cell death,learning defective,locomotor rhythm defective,visual behavior defective" "sensory neuron & labellar taste bristle,gustatory receptor neuron,large labellar taste bristle,wing,posterior scutellar bristle,pupa,bouton,synapse,embryonic/larval fat body,labellar taste bristle,somatic clone,adult olfactory receptor neuron Or22,scutellum,wing | pharate adult stage,photoreceptor cell" FBgn0266841 CR45303 http://flybase.net/reports/FBgn0266841.html non_protein_coding_gene CR45303 16-Dec-15 2015_12 FBgn0031627 CG15630 http://flybase.net/reports/FBgn0031627.html protein_coding_gene "15630, CG31970, CT35785" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set" CG15630 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0000858 fs(1)M52 female sterile (1) M52 http://flybase.net/reports/FBgn0000858.html gene 16-Dec-15 2015_12 female sterile FBgn0266592 CR45117 http://flybase.net/reports/FBgn0266592.html non_protein_coding_gene CR45117 16-Dec-15 2015_12 FBgn0065104 snmRNA:158 small non-messenger RNA 158 http://flybase.net/reports/FBgn0065104.html FBgn0053749 non_protein_coding_gene "CR33749, Dm-158" CR33749 16-Dec-15 2015_12 FBgn0065158 l(3)SH047 lethal (3) SH047 http://flybase.net/reports/FBgn0065158.html gene l(2)SH3 047 16-Dec-15 2015_12 "lethal,recessive" FBgn0002612 M(3)63B Minute (3) 63B http://flybase.net/reports/FBgn0002612.html gene "l(3)63bf, M(3)63Bf, l(3)63Bf, M(3)LS3" 16-Dec-15 2015_12 "lethal,recessive" FBgn0024603 olfS51 olfactory S51 http://flybase.net/reports/FBgn0024603.html gene 16-Dec-15 2015_12 smell perception defective FBgn0035994 CG14179 http://flybase.net/reports/FBgn0035994.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019779 l(1)30 lethal (1) 30 http://flybase.net/reports/FBgn0019779.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050026 CG30026 http://flybase.net/reports/FBgn0050026.html protein_coding_gene CG30026 16-Dec-15 2015_12 viable FBgn0052675 Tango5 Transport and Golgi organization 5 http://flybase.net/reports/FBgn0052675.html FBgn0030229 protein_coding_gene "0009306=protein secretion, 0007030=Golgi organization" 0005783=endoplasmic reticulum "TANGO5, CG32675, CG1534" CG32675 16-Dec-15 2015_12 ENSDARG00000012450(tmem49) WBGene00012559(Y37D8A.22) ENSXETG00000010736(Q68EQ9_XENTR) ENSMUSG00000018171(Tmem49) ENSG00000062716(VMP1) viable FBgn0035588 CG10672 http://flybase.net/reports/FBgn0035588.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process 0005777=peroxisome DHRS4 "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG10672 16-Dec-15 2015_12 ENSDARG00000021135(zgc:65987) YNL202W(SPS19) WBGene00000976(dhs-13) ENSXETG00000022566(dhrs4) "ENSMUSG00000022210(Dhrs4),ENSMUSG00000022209(Dhrs2)" "ENSG00000157326(DHRS4),ENSG00000187630(DHRS4L2)" viable FBgn0002804 ms(1)19Fc male sterile (1) 19Fc http://flybase.net/reports/FBgn0002804.html gene 16-Dec-15 2015_12 male sterile FBgn0069230 gl(2L)266-11 gl(2L)266-11 http://flybase.net/reports/FBgn0069230.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment,filzkorper" FBgn0063379 snoRNA:U31:54Ec snoRNA:U31:54Ec http://flybase.net/reports/FBgn0063379.html snoRNA_gene "U31snoRNA, CR32898" CR32898 16-Dec-15 2015_12 FBgn0011844 tRNA:D2:69F transfer RNA:asp2:69F http://flybase.net/reports/FBgn0011844.html "FBgn0052125, FBgn0060265" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033458=GAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002602.trna20-AspGTC, tRNA[Asp-GTC], tRNA:D:GTC:AE002602, chr3L.trna26-AspGTC, tRNA[[Asp]], CR32125, tRNA:asp2:69F" CR32125 16-Dec-15 2015_12 FBgn0040766 CG13235 http://flybase.net/reports/FBgn0040766.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036900 CG8765 http://flybase.net/reports/FBgn0036900.html protein_coding_gene "0046331=lateral inhibition, 0048813=dendrite morphogenesis" IPR006578=MADF domain CG8765 16-Dec-15 2015_12 WBGene00019218(H20J04.3) "neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "dorsal multidendritic neuron ddaD,ventral multidendritic neuron vdaB,chaeta,trichogen cell,supernumerary,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0262460 mir-2a-2 mir-2a-2 stem loop http://flybase.net/reports/FBgn0262460.html "FBgn0046825, FBgn0262328" miRNA_gene "0007476=imaginal disc-derived wing morphogenesis, 0045947=negative regulation of translational initiation, 0060548=negative regulation of cell death" "CR32966, mir-2, miR-2a-2, 2a-2, miR2-a, miR2a, mir-2a-2, miR-2a, dme-miR-2a, miR-2, CR43035, dme-mir-2a-2, mir-2a, miR2" CR43035 16-Dec-15 2015_12 embryonic stage -- adult stage viable FBgn0267724 CR46057 http://flybase.net/reports/FBgn0267724.html non_protein_coding_gene CR46057 16-Dec-15 2015_12 FBgn0005584 MabF7D6 MabF7D6 http://flybase.net/reports/FBgn0005584.html "FBgn0004489, FBgn0004909" gene 0004674=protein serine/threonine kinase activity 0006468=protein phosphorylation 0019897=extrinsic component of plasma membrane F7D6 16-Dec-15 2015_12 FBgn0259824 Hip14 Huntingtin-interacting protein 14 http://flybase.net/reports/FBgn0259824.html "FBgn0036555, FBgn0004715" protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" "0007268=synaptic transmission, 0050714=positive regulation of protein secretion, 0018345=protein palmitoylation, 0007283=spermatogenesis, 0016079=synaptic vesicle exocytosis" "0008021=synaptic vesicle, 0045202=synapse, 0005794=Golgi apparatus" "CG 6017, dHIP14, htt-interacting protein 14, 3L1, l(3)72Ad, CG6017, lethal (3) 72Ad, ankyrin domain, hip14" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG6017 16-Dec-15 2015_12 ENSDARG00000070441(zdhhc17) "YDR264C(AKR1),YOR034C(AKR2)" WBGene00019257(H32C10.3) "ENSXETG00000014315(ZDHHC17),ENSXETG00000004429(ZDHHC13)" ENSMUSG00000035798(Zdhhc17) "ENSG00000186908(ZDHHC17),ENSG00000177054(ZDHHC13)" FBgn0265218 fs(2)Z2-931 http://flybase.net/reports/FBgn0265218.html gene 16-Dec-15 2015_12 female sterile FBgn0000977 fs(2)HO144 female sterile (2) HO144 http://flybase.net/reports/FBgn0000977.html gene fs(2)144A 16-Dec-15 2015_12 FBgn0011670 Mst57Dc Male-specific transcript 57Dc http://flybase.net/reports/FBgn0011670.html FBgn0002859 protein_coding_gene "0032504=multicellular organism reproduction, 0018991=oviposition, 0045297=post-mating behavior" "0005615=extracellular space, 0005576=extracellular region" "male-specific RNA 57dc, mst-1, mst(2)ag-1, Mst57dc for male accessory gland protein, CG4986, male specific transcript 57D, Mst75Dc, Acp57Dc, Male-specific RNA 57Dc" CG4986 16-Dec-15 2015_12 viable FBgn0016661 H2 haemolymph protein 2 http://flybase.net/reports/FBgn0016661.html gene 16-Dec-15 2015_12 FBgn0019828 dj don juan http://flybase.net/reports/FBgn0019828.html protein_coding_gene 0003677=DNA binding "0007291=sperm individualization, 0007283=spermatogenesis, 0007286=spermatid development" "0005634=nucleus, 0016007=mitochondrial derivative, 0005739=mitochondrion, 0005930=axoneme, 0031514=motile cilium" "CG1980, Dj, don-juan, bs02h03.y1, DJ, Don Juan, Don-juan" CG1980 16-Dec-15 2015_12 " spermatogenesis && adult stage | male , spermatogenesis && adult stage " " spermatid

, testis

, spermatid axoneme

" spermatogenesis && adult stage testis

"male sterile,fertile,male,viable" "investment cone,individualization stage spermatid,spermatid,Nebenkern" FBgn0001170 H2.0 Homeodomain protein 2.0 http://flybase.net/reports/FBgn0001170.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus CG11607 "IPR020479=Homeodomain, metazoa, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG11607 16-Dec-15 2015_12 ENSXETG00000002734(HLX) ENSMUSG00000039377(Hlx) ENSG00000136630(HLX) " embryonic stage -- adult stage , embryonic stage | stage >=11 , embryonic stage | stage >11 " " visceral mesoderm &&of embryonic/larval midgut

, visceral mesoderm

, ectoderm

" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC03340 I -1.03811596 -3.330961788 -0.917033195 -1.251390723 1.374880874 0.496682223 FBgn0027793 CG14787 http://flybase.net/reports/FBgn0027793.html protein_coding_gene EG:BACN32G11.4 IPR029045=ClpP/crotonase-like domain CG14787 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0037543 CG10903 http://flybase.net/reports/FBgn0037543.html protein_coding_gene 0008757=S-adenosylmethionine-dependent methyltransferase activity "0008152=metabolic process, 0022008=neurogenesis" "IPR022238=Uncharacterised protein family, methyltransferase, Williams-Beuren syndrome, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR013216=Methyltransferase type 11" CG10903 16-Dec-15 2015_12 YCR047C(BUD23) WBGene00016166(C27F2.4) ENSXETG00000010343(Q5I031_XENTR) ENSMUSG00000005378(Wbscr22) ENSG00000071462(WBSCR22) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0036822 NijB Ninjurin B http://flybase.net/reports/FBgn0036822.html protein_coding_gene 0016937=short-branched-chain-acyl-CoA dehydrogenase activity "0042246=tissue regeneration, 0007155=cell adhesion, 0046331=lateral inhibition" 0016021=integral component of membrane "Ninjurin B, NijB, CG11637" IPR007007=Ninjurin CG11637 16-Dec-15 2015_12 "viable,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell" FBgn0038311 CG14864 http://flybase.net/reports/FBgn0038311.html FBgn0061455 protein_coding_gene BcDNA:AT13896 CG14864 16-Dec-15 2015_12 FBgn0015893 anon-84Fb T3 transcript http://flybase.net/reports/FBgn0015893.html gene T3 16-Dec-15 2015_12 FBgn0050400 CG30400 http://flybase.net/reports/FBgn0050400.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031357 mRpL48 mitochondrial ribosomal protein L48 http://flybase.net/reports/FBgn0031357.html protein_coding_gene 0003735=structural constituent of ribosome 0032543=mitochondrial translation 0005762=mitochondrial large ribosomal subunit "CG17642, MRP-L48" "IPR027486=Ribosomal protein S10 domain, IPR027487=Mitochondrial ribosomal protein L48" CG17642 16-Dec-15 2015_12 ENSDARG00000035167 WBGene00016989(CD4.3) ENSXETG00000023199(MRPL48) ENSMUSG00000030706(Mrpl48) ENSG00000175581(MRPL48) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC00506 K 0.217576332 -1.126800122 -0.352704555 0.015061553 1.631085042 0.50270573 FBgn0029719 CG15473 http://flybase.net/reports/FBgn0029719.html protein_coding_gene CG15473 16-Dec-15 2015_12 viable DRSC18056 K 0.526024992 0.755893012 0.235942662 0.040160142 0.259373796 1.648847487 FBgn0035209 msd1 mitotic spindle density 1 http://flybase.net/reports/FBgn0035209.html protein_coding_gene "0007020=microtubule nucleation, 0007052=mitotic spindle organization" "0005875=microtubule associated complex, 0070652=HAUS complex" "CG13914, mitotic spindle density 1, msd1" CG13914 16-Dec-15 2015_12 "viable,female sterile,meiotic cell cycle defective,mitotic cell cycle defective,fertile" spindle FBgn0259738 CG42392 http://flybase.net/reports/FBgn0259738.html protein_coding_gene CG42392 16-Dec-15 2015_12 FBgn0042184 CG18189 http://flybase.net/reports/FBgn0042184.html protein_coding_gene 16-Dec-15 2015_12 FBgn0020508 Ag5r2 Antigen 5-related 2 http://flybase.net/reports/FBgn0020508.html FBgn0030579 protein_coding_gene 0005576=extracellular region "CG9540, Agr2" "IPR002413=Ves allergen, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG9540 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" " larval stage , embryonic stage | stage 15 , embryonic stage | stage >=15 " " midgut constriction 3 | posterior to

, posterior embryonic/larval midgut | restricted

" viable FBgn0031999 CG8419 http://flybase.net/reports/FBgn0031999.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0051865=protein autoubiquitination 0005622=intracellular "IPR014756=Immunoglobulin E-set, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000315=B-box-type zinc finger, IPR017907=Zinc finger, RING-type, conserved site, IPR017868=Filamin/ABP280 repeat-like, IPR018957=Zinc finger, C3HC4 RING-type, IPR013783=Immunoglobulin-like fold, IPR001841=Zinc finger, RING-type, IPR001298=Filamin/ABP280 repeat" CG8419 16-Dec-15 2015_12 WBGene00003599(nhl-3) ENSXETG00000017042(TRIM45) ENSMUSG00000033233(Trim45) ENSG00000134253(TRIM45) viable FBgn0011179 l(1)291-82 lethal (1) 291-82 http://flybase.net/reports/FBgn0011179.html FBgn0010199 gene 291-82 16-Dec-15 2015_12 "lethal,recessive" FBgn0022343 CG3760 http://flybase.net/reports/FBgn0022343.html protein_coding_gene "anon-EST:fe2C9, unnamed, anon-fast-evolving-2C9, anon2C9, anon-fe2C9" IPR026806=Protein CDV3 CG3760 16-Dec-15 2015_12 ENSXETG00000001859(TGas130k19.1) "viable,fertile" FBgn0267465 CR45815 http://flybase.net/reports/FBgn0267465.html non_protein_coding_gene CR45815 16-Dec-15 2015_12 FBgn0050316 tRNA:CR30316 transfer RNA:CR30316 http://flybase.net/reports/FBgn0050316.html FBgn0060088 tRNA_gene 0033429=CGU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:R:ACG:AE002769-e, AE002769.trna17-ArgACG, CR30316, chr2R.trna9-ArgACG" CR30316 16-Dec-15 2015_12 FBgn0043897 gsb::prd gsb::prd http://flybase.net/reports/FBgn0043897.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0052557 CG32557 http://flybase.net/reports/FBgn0052557.html FBgn0030875 protein_coding_gene "0005507=copper ion binding, 0052716=hydroquinone:oxygen oxidoreductase activity" 0055114=oxidation-reduction process "CG7871, MCO4" "IPR008972=Cupredoxin, IPR002355=Multicopper oxidase, copper-binding site, IPR011707=Multicopper oxidase, type 3, IPR011706=Multicopper oxidase, type 2, IPR001117=Multicopper oxidase, type 1" CG32557 16-Dec-15 2015_12 "YMR058W(FET3),YFL041W(FET5)" WBGene00009008(F21D5.3) viable FBgn0011103 l(1)Q64 lethal (1) Q64 http://flybase.net/reports/FBgn0011103.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0031831 COX5BL Cytochrome c oxidase subunit 5B-like http://flybase.net/reports/FBgn0031831.html protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" "0005751=mitochondrial respiratory chain complex IV, 0005739=mitochondrion" "CG11043, COXB, Cytochrome c oxidase polypeptide Vb, Vb, Cytochrome c oxidase Polypeptide VB" "IPR002124=Cytochrome c oxidase, subunit Vb" CG11043 16-Dec-15 2015_12 "ENSDARG00000015978(zgc:86599),ENSDARG00000068738(zgc:153978),ENSDARG00000011208(LOC100002384)" "viable,visible" trichogen cell FBgn0005701 l(1)TK104 lethal (1) TK104 http://flybase.net/reports/FBgn0005701.html gene l104 16-Dec-15 2015_12 "lethal,recessive" eye FBgn0011723 byn brachyenteron http://flybase.net/reports/FBgn0011723.html FBgn0014890 protein_coding_gene "0042803=protein homodimerization activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity" "0001700=embryonic development via the syncytial blastoderm, 0007494=midgut development, 0006355=regulation of transcription, DNA-templated, 0007442=hindgut morphogenesis, 0007443=Malpighian tubule morphogenesis, 0007509=mesoderm migration involved in gastrulation, 0001709=cell fate determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007280=pole cell migration" 0005634=nucleus "D-Trg, aproctous, D-TRA, trg, Trg, apro, T-related gene, Tra, Brachyenteron, Dm-BYN, brachyury, CG7260, T related antigen, dm-Trg, Byn, byn/apro, DTrg" "IPR002070=Transcription factor, Brachyury, IPR018186=Transcription factor, T-box, conserved site, IPR001699=Transcription factor, T-box, IPR008967=p53-like transcription factor, DNA-binding" CG7260 16-Dec-15 2015_12 "WBGene00006557(tbx-38),WBGene00006556(tbx-37)" "ENSXETG00000005370(T),ENSXETG00000026572(T)" "ENSMUSG00000062327(T),ENSMUSG00000026572(Tbx19)" "ENSG00000164458(T),ENSG00000143178(TBX19)" " embryonic stage | stage 5-10 , embryonic stage | stage 5 , embryonic stage , embryonic stage | cycle 14 " " proctodeum

,

0-10% egg length , embryonic/larval hindgut

,

posterior ,

0-20% egg length , anal pad

" " embryonic stage , embryonic stage | stage 5-10 " " embryonic/larval hindgut

, proctodeum

, anal pad

" "lethal,recessive,short lived,partially,female sterile,viable,body color defective" "proctodeum,hindgut proper primordium,embryonic anal pad,egg chamber,adult Malpighian tubule Type II cell,longitudinal visceral muscle primordium,germline cell,longitudinal visceral muscle fiber,circular visceral muscle fiber,midgut constriction 1,midgut constriction 2,midgut constriction 3,embryonic/larval hindgut,embryonic/larval dorsal vessel,pericardial cell,A1-7 dorsal acute muscle 1,Malpighian tubule,midgut constriction,head mesoderm,ectopic,mesoderm,mesothoracic tergum" FBgn0266982 CR45433 http://flybase.net/reports/FBgn0266982.html non_protein_coding_gene CR45433 16-Dec-15 2015_12 FBgn0031622 CG3251 http://flybase.net/reports/FBgn0031622.html protein_coding_gene 0004843=ubiquitin-specific protease activity 0016579=protein deubiquitination IPR003323=OTU domain CG3251 16-Dec-15 2015_12 ENSDARG00000054374(otul) ENSMUSG00000041718 ENSG00000101901(ALG13) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,scutellar bristle" FBgn0082166 ph-PRE ph-PRE http://flybase.net/reports/FBgn0082166.html regulatory_region Ph 16-Dec-15 2015_12 FBgn0060293 smet smetana http://flybase.net/reports/FBgn0060293.html gene 0010378=temperature compensation of the circadian clock 16-Dec-15 2015_12 "touch sensitivity defective,locomotor behavior defective,locomotor rhythm defective" FBgn0030377 CG1924 http://flybase.net/reports/FBgn0030377.html protein_coding_gene "0005509=calcium ion binding, 0051082=unfolded protein binding" 0006457=protein folding "0005783=endoplasmic reticulum, 0016021=integral component of membrane" "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR009033=Calreticulin/calnexin, P domain, IPR001580=Calreticulin/calnexin, IPR018124=Calreticulin/calnexin, conserved site" CG1924 16-Dec-15 2015_12 "ENSDARG00000037488(canx),ENSDARG00000009315(clgn)" YAL058W(CNE1) WBGene00000567(cnx-1) ENSXETG00000008408(canx) "ENSMUSG00000020368(Canx),ENSMUSG00000002190(Clgn)" "ENSG00000127022(CANX),ENSG00000153132(CLGN)" FBgn0050404 Tango11 Transport and Golgi organization 11 http://flybase.net/reports/FBgn0050404.html "FBgn0025252, FBgn0045785, FBgn0046223" protein_coding_gene 0009306=protein secretion 0005783=endoplasmic reticulum "Transport and Golgi organization, anon-EST:fe1F11, BEST:LD33633, anon-fast-evolving-1F11, tango11, CG30404, BcDNA:LD22567, TANGO11" IPR008518=FATE/Miff/Tango-11 CG30404 16-Dec-15 2015_12 "ENSDARG00000053753(mff),ENSDARG00000039203(zgc:110130)" ENSXETG00000014760(MFF) ENSMUSG00000026150(Mff) ENSG00000168958(MFF) "developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,viable,visible" "trichogen cell,tormogen cell" FBgn0003327 scal scabrous-like http://flybase.net/reports/FBgn0003327.html gene 16-Dec-15 2015_12 "visible,partially lethal - majority die,female sterile,reduced" "eye,abdomen & macrochaeta,scutellar bristle,wing,wing vein L2,posterior crossvein" FBgn0003273 Rp21 Ribosomal protein 21 http://flybase.net/reports/FBgn0003273.html gene 0003735=structural constituent of ribosome 0006412=translation 0005840=ribosome "r-protein 21, rp21" 16-Dec-15 2015_12 FBgn0083166 Nrdp1 Nrdp1 http://flybase.net/reports/FBgn0083166.html gene dNrdp1 16-Dec-15 2015_12 "neuroanatomy defective,flight defective" dopaminergic neuron | adult stage FBgn0264299 CG43777 http://flybase.net/reports/FBgn0264299.html FBgn0034979 protein_coding_gene 0005576=extracellular region "CG13569-3, CG13569" "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG43777 16-Dec-15 2015_12 viable FBgn0086053 snoRNA:Me18S-G1358a http://flybase.net/reports/FBgn0086053.html snoRNA_gene "Me18S-Gm1358a, CR34682, Me18S-G1358a" CR34682 16-Dec-15 2015_12 FBgn0260276 GSd211 http://flybase.net/reports/FBgn0260276.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0041120 l(2)cl-L3 lethal (2) cell lethal L3 http://flybase.net/reports/FBgn0041120.html gene cl2L3 16-Dec-15 2015_12 lethal FBgn0053701 CR33701 http://flybase.net/reports/FBgn0053701.html pseudogene_attribute CR33701 16-Dec-15 2015_12 FBgn0066354 l(3)99DEa lethal (3) 99DEa http://flybase.net/reports/FBgn0066354.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010522 l(2)02836a lethal (2) 02836a http://flybase.net/reports/FBgn0010522.html gene l(2)02836 16-Dec-15 2015_12 "lethal,recessive" FBgn0021979 l(2)k09913 lethal (2) k09913 http://flybase.net/reports/FBgn0021979.html protein_coding_gene "1(2)k09913, CG3082" "IPR029058=Alpha/Beta hydrolase fold, IPR008547=Protein of unknown function DUF829, TMEM53" CG3082 16-Dec-15 2015_12 ENSDARG00000058345(si:dkey-5i3.5) "lethal,recessive" FBgn0000793 fs(1)de3 female sterile (1) defective eggs 3 http://flybase.net/reports/FBgn0000793.html gene de3 16-Dec-15 2015_12 female sterile "endochorion,dorsal appendage,chorion" FBgn0065105 snmRNA:157 small non-messenger RNA 157 http://flybase.net/reports/FBgn0065105.html FBgn0053707 non_protein_coding_gene "Dm-157, CR33707" CR33707 16-Dec-15 2015_12 FBgn0261717 DJ1026 http://flybase.net/reports/FBgn0261717.html gene 16-Dec-15 2015_12 FBgn0038733 CG11407 http://flybase.net/reports/FBgn0038733.html protein_coding_gene "0003824=catalytic activity, 0005324=long-chain fatty acid transporter activity" 0008152=metabolic process "IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site, IPR025110=AMP-binding enzyme C-terminal domain" CG11407 16-Dec-15 2015_12 viable FBgn0267169 CR45609 http://flybase.net/reports/FBgn0267169.html non_protein_coding_gene CR45609 16-Dec-15 2015_12 FBgn0014107 anon-4Cf anon-4Cf http://flybase.net/reports/FBgn0014107.html gene "Transcript 16, T16" 16-Dec-15 2015_12 FBgn0034436 CG11961 http://flybase.net/reports/FBgn0034436.html protein_coding_gene CG11961-PA IPR007484=Peptidase M28 CG11961 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0263510 nclb no child left behind http://flybase.net/reports/FBgn0263510.html "FBgn0259115, FBgn0033562" protein_coding_gene 0031490=chromatin DNA binding "0036098=male germ-line stem cell maintenance, 0007281=germ cell development, 0030723=ovarian fusome organization, 0010468=regulation of gene expression, 0030707=ovarian follicle cell development, 0008584=male gonad development, 0036099=female germ-line stem cell maintenance" "0005634=nucleus, 0035327=transcriptionally active chromatin" CG6751 "IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG6751 16-Dec-15 2015_12 ENSDARG00000015921(pwp1) YLR196W(PWP1) WBGene00010435(JC8.2) ENSXETG00000016975(PWP1) ENSMUSG00000001785(Pwp1) ENSG00000136045(PWP1) FBgn0003238 rapid-exhaustion rapid exhaustion http://flybase.net/reports/FBgn0003238.html gene rex 16-Dec-15 2015_12 "bang sensitive,lethal,heat sensitive,uncoordinated,neurophysiology defective" FBgn0026338 Su(tor)2-280-28 Su(tor)2-280-28 http://flybase.net/reports/FBgn0026338.html gene 16-Dec-15 2015_12 FBgn0040581 CG15496 http://flybase.net/reports/FBgn0040581.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031364 CG17648 http://flybase.net/reports/FBgn0031364.html FBgn0063283 protein_coding_gene BcDNA:GH02930 CG17648 16-Dec-15 2015_12 viable FBgn0041121 l(2)45Bf lethal (2) 45Bf http://flybase.net/reports/FBgn0041121.html gene 16-Dec-15 2015_12 lethal FBgn0031494 CG17219 http://flybase.net/reports/FBgn0031494.html protein_coding_gene "IPR019410=Lysine methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG17219 16-Dec-15 2015_12 YIL110W(MNI1) WBGene00010450(K01A11.2) ENSXETG00000012806(C1orf156) ENSMUSG00000041396(2810422O20Rik) ENSG00000171806(METTL18) viable FBgn0016835 l(1)MZ3 lethal (1) MZ3 http://flybase.net/reports/FBgn0016835.html gene M3 16-Dec-15 2015_12 "lethal,recessive" FBgn0003361 sesD stress-sensitive D http://flybase.net/reports/FBgn0003361.html gene 16-Dec-15 2015_12 FBgn0044027 Ori66Dë_ Ori66Dë_ http://flybase.net/reports/FBgn0044027.html origin_of_replication "ori-beta, Ori-beta, Oribeta" 16-Dec-15 2015_12 FBgn0259636 B0339 http://flybase.net/reports/FBgn0259636.html gene 16-Dec-15 2015_12 visible wing FBgn0262420 mir-318 mir-318 stem loop http://flybase.net/reports/FBgn0262420.html "FBgn0067686, FBgn0262264" miRNA_gene "0030381=chorion-containing eggshell pattern formation, 0007307=eggshell chorion gene amplification" "CR42971, CR33622, Mir-318, mir-318, miR-318, dme-mir-318" CR42971 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing vein" FBgn0027497 Madm MLF1-adaptor molecule http://flybase.net/reports/FBgn0027497.html FBgn0062034 protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0042803=protein homodimerization activity, 0005524=ATP binding" "0042127=regulation of cell proliferation, 0006468=protein phosphorylation, 0009306=protein secretion, 0008361=regulation of cell size, 0006888=ER to Golgi vesicle-mediated transport" "0005829=cytosol, 0012505=endomembrane system, 0005794=Golgi apparatus" "CG1098, Mif1 adaptor molecule, BcDNA:LD28657, anon-WO0118547.406, MADM, lincRNA.S6031, dMADM" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG1098 16-Dec-15 2015_12 "ENSDARG00000056089(si:dkey-12h9.7),ENSDARG00000032951(nrbp2),ENSDARG00000009626(zgc:194780)" WBGene00010427(H37N21.1) ENSXETG00000012522(Q6GL31_XENTR) ENSMUSG00000029148(Nrbp1) ENSG00000115216(NRBP1) "viable,visible,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,partially lethal - majority die" "trichogen cell,head,eye,cell autonomous,somatic clone,ommatidium,rhabdomere | cell autonomous | somatic clone,photoreceptor cell" DRSC25999 K 0.815387428 -0.146710175 -0.063836704 -1.001902379 -0.268540573 1.646136044 FBgn0014909 anon-4Fc anon-4Fc http://flybase.net/reports/FBgn0014909.html gene 16-Dec-15 2015_12 FBgn0040744 CG12711 http://flybase.net/reports/FBgn0040744.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031441 CG9962 http://flybase.net/reports/FBgn0031441.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0016055=Wnt signaling pathway, 0006468=protein phosphorylation" 0005737=cytoplasm CKIa-like "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR017441=Protein kinase, ATP binding site" CG9962 16-Dec-15 2015_12 viable FBgn0015616 Cazip1 Caz-interacting protein 1 http://flybase.net/reports/FBgn0015616.html gene 16-Dec-15 2015_12 FBgn0019654 smu small mushroom bodies http://flybase.net/reports/FBgn0019654.html gene 0016319=mushroom body development 16-Dec-15 2015_12 "female sterile,locomotor behavior defective,partially lethal - majority die,female limited" "ellipsoid body,nodulus,adult mushroom body,calyx of larval mushroom body,calyx of adult mushroom body,lobe system of adult mushroom body" FBgn0039494 grass Gram-positive Specific Serine protease http://flybase.net/reports/FBgn0039494.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006952=defense response, 0050830=defense response to Gram-positive bacterium, 0045087=innate immune response, 0006508=proteolysis, 0045752=positive regulation of Toll signaling pathway" 0005576=extracellular region "gram-positive specific serine protease, SP1, c-SP1, Gram-positive-specific serine protease, SP2, CG5896, Grass" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR006604=Disulphide knot CLIP, IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG5896 16-Dec-15 2015_12 "immune response defective,viable,recessive" FBgn0053429 5SrRNA:CR33429 5SrRNA:CR33429 http://flybase.net/reports/FBgn0053429.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33429 CR33429 16-Dec-15 2015_12 FBgn0036906 CG14102 http://flybase.net/reports/FBgn0036906.html protein_coding_gene CG14102 16-Dec-15 2015_12 viable FBgn0019653 sng snaggle http://flybase.net/reports/FBgn0019653.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 "lethal,recessive" FBgn0015443 l(1)7DEa lethal (1) 7DEa http://flybase.net/reports/FBgn0015443.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053725 CG33725 http://flybase.net/reports/FBgn0053725.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33725 16-Dec-15 2015_12 FBgn0264892 CR44083 http://flybase.net/reports/FBgn0264892.html non_protein_coding_gene CR44083 16-Dec-15 2015_12 FBgn0086668 snoRNA:ë¬28S-3436a snoRNA:ë¬28S-3436a http://flybase.net/reports/FBgn0086668.html "FBgn0065056, FBgn0082956, FBgn0053751" snoRNA_gene 0005730=nucleolus "snoR708, Psi 28S-3436a(SnoR708), Psi28S-3436a, snoRNA:708, Dm-708, CR33751, psi28S-3436a" CR33751 16-Dec-15 2015_12 FBgn0060875 l(3)S045822 lethal (3) S045822 http://flybase.net/reports/FBgn0060875.html gene 0458/22 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060805 l(3)S056003b lethal (3) S056003b http://flybase.net/reports/FBgn0060805.html gene 0560/03 16-Dec-15 2015_12 "viable,lethal" FBgn0001920 l(2)25Ca lethal (2) 25Ca http://flybase.net/reports/FBgn0001920.html gene "l(2)2[DTS], DTS, l(2)DCS, l(2)25AD" 16-Dec-15 2015_12 "lethal,dominant,cold sensitive,heat sensitive,recessive" FBgn0041113 l(3)cl-L5 lethal (3) cell lethal L5 http://flybase.net/reports/FBgn0041113.html gene cl3L5 16-Dec-15 2015_12 lethal FBgn0021771 ms(3)P50 ms(3)P50 http://flybase.net/reports/FBgn0021771.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0015459 l(2)37CDd lethal (2) 37CDd http://flybase.net/reports/FBgn0015459.html gene l(2)E2 16-Dec-15 2015_12 "lethal,recessive" FBgn0051233 CG31233 http://flybase.net/reports/FBgn0051233.html "FBgn0038898, FBgn0044563, FBgn0044757" protein_coding_gene "0008270=zinc ion binding, 0004177=aminopeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis "CG5839, anon-WO0140519.125, anon-WO0140519.65" "IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571=ERAP1-like C-terminal domain" CG31233 16-Dec-15 2015_12 FBgn0038402 Fer2 48 related 2 http://flybase.net/reports/FBgn0038402.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity" "0045475=locomotor rhythm, 0006979=response to oxidative stress, 0048699=generation of neurons, 1903204=negative regulation of oxidative stress-induced neuron death, 0006355=regulation of transcription, DNA-templated, 0010628=positive regulation of gene expression" 0005634=nucleus "48-related 2, fer2, bHLHa33, 48-related-2, CG5952" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG5952 16-Dec-15 2015_12 ENSXETG00000005841(NHLH1) ENSG00000122691(TWIST1) "viable,fertile,locomotor rhythm defective" "l-LNv neuron,s-LNv neuron,LNd neuron" FBgn0005041 E(var)25F Enhancer of variegation 25F http://flybase.net/reports/FBgn0005041.html gene "unnamed, E-var" 16-Dec-15 2015_12 FBgn0040918 schlank schlank http://flybase.net/reports/FBgn0040918.html "FBgn0026692, FBgn0028312, FBgn0029852, FBgn0040141" protein_coding_gene "0003677=DNA binding, 0050291=sphingosine N-acyltransferase activity" "0050995=negative regulation of lipid catabolic process, 0046889=positive regulation of lipid biosynthetic process, 0006641=triglyceride metabolic process, 0046513=ceramide biosynthetic process, 0032933=SREBP signaling pathway" "0005886=plasma membrane, 0016021=integral component of membrane, 0005783=endoplasmic reticulum" "l(1)G0489, longevity, CG15898, Psc, lag1, l(1)G0061, DLag1, CG3576, Dlag1, l(1)G0365, Lag1, DLAG1, Longevity assurance gene 1, lon" "IPR009057=Homeodomain-like, IPR016439=Ceramide synthase component Lag1/Lac1, IPR001356=Homeobox domain, IPR006634=TRAM/LAG1/CLN8 homology domain" CG3576 16-Dec-15 2015_12 "ENSDARG00000002365(lass5),ENSDARG00000053583,ENSDARG00000018619(LOC100330155)" "YHL003C(LAG1),YKL008C(LAC1)" "WBGene00002043(hyl-1),WBGene00002044(hyl-2)" "ENSXETG00000016207(LASS6),ENSXETG00000013344(LASS5)" "ENSMUSG00000027035(Lass6),ENSMUSG00000023021(Lass5)" "ENSG00000139624(CERS5),ENSG00000172292(CERS6)" "lethal - all die before end of larval stage,some die during larval stage,small body,developmental rate defective,female sterile germline-dependent,germline clone,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,viable,visible" trichogen cell DRSC18313 I 1.56525998 1.25747468 0.513895389 0.738167338 -0.656069603 -1.1335483 FBgn0016907 l(3)X2 lethal (3) X2 http://flybase.net/reports/FBgn0016907.html gene X2 16-Dec-15 2015_12 FBgn0267706 CR46039 http://flybase.net/reports/FBgn0267706.html non_protein_coding_gene CR46039 16-Dec-15 2015_12 FBgn0082983 snoRNA:ë¬28S-2626 snoRNA:ë¬28S-2626 http://flybase.net/reports/FBgn0082983.html snoRNA_gene "Psi 28S-2626, psi28S-2626, chr3R:26033540..26033785, Psi28S-2626, CR34629" CR34629 16-Dec-15 2015_12 FBgn0042685 Tirant\pol pol http://flybase.net/reports/FBgn0042685.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "ORF2, reverse transcriptase, pol" "IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0259574 B2017 http://flybase.net/reports/FBgn0259574.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,partially,some die during pupal stage" "leg,unguis,arista,proboscis" FBgn0029098 anon-89Be anon-89Be http://flybase.net/reports/FBgn0029098.html gene 16-Dec-15 2015_12 FBgn0029892 CG3184 http://flybase.net/reports/FBgn0029892.html protein_coding_gene 0032451=demethylase activity 0017183=peptidyl-diphthamide biosynthetic process from peptidyl-histidine 0005737=cytoplasm "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG3184 16-Dec-15 2015_12 ENSDARG00000062083(wdr85) YBR246W(RRT2) ENSMUSG00000026975(Wdr85) ENSG00000148399(WDR85) viable FBgn0014933 anon-87Eb anon-87Eb http://flybase.net/reports/FBgn0014933.html gene "B transcript, B, Transcription unit B" 16-Dec-15 2015_12 FBgn0060610 l(3)S090308 lethal (3) S090308 http://flybase.net/reports/FBgn0060610.html gene 0903/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0025341 anon-58Fb anon-58Fb http://flybase.net/reports/FBgn0025341.html gene 12.2 16-Dec-15 2015_12 FBgn0020257 Ppa Partner of paired http://flybase.net/reports/FBgn0020257.html FBgn0034764 protein_coding_gene 0004842=ubiquitin-protein transferase activity "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0006511=ubiquitin-dependent protein catabolic process" "0000152=nuclear ubiquitin ligase complex, 0019005=SCF ubiquitin ligase complex" "PPA, FBXL14, I-55, partner of paired, ppa, CG9952, Ppa" "IPR001810=F-box domain, IPR003590=Leucine-rich repeat, ribonuclease inhibitor subtype, IPR006553=Leucine-rich repeat, cysteine-containing subtype" CG9952 16-Dec-15 2015_12 "ENSDARG00000045801(fbxl14b),ENSDARG00000034497(fbxl14a)" YJR052W(RAD7) ENSMUSG00000030019(Fbxl14) ENSG00000171823(FBXL14) "chemical sensitive,viable,visible,body color defective" mesothoracic tergum FBgn0267299 CR45735 http://flybase.net/reports/FBgn0267299.html non_protein_coding_gene CR45735 16-Dec-15 2015_12 FBgn0038000 CG10014 http://flybase.net/reports/FBgn0038000.html protein_coding_gene "IPR003117=cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, IPR000048=IQ motif, EF-hand binding site" CG10014 16-Dec-15 2015_12 viable FBgn0263093 CR43361 http://flybase.net/reports/FBgn0263093.html pseudogene_attribute CG32021 CR43361 16-Dec-15 2015_12 FBgn0011626 l(2)T56j5 lethal (2) T56j5 http://flybase.net/reports/FBgn0011626.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0259838 Su(Ste):CR42407 Su(Ste):CR42407 http://flybase.net/reports/FBgn0259838.html non_protein_coding_gene "CR42407, RR42201" CR42407 16-Dec-15 2015_12 FBgn0263534 mir-4960 mir-4960 stem loop http://flybase.net/reports/FBgn0263534.html miRNA_gene "CR43519, dme-mir-4960" CR43519 16-Dec-15 2015_12 FBgn0061115 l(3)S005515b lethal (3) S005515b http://flybase.net/reports/FBgn0061115.html gene 0055/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0045977 PdL35B1 PdL35B1 http://flybase.net/reports/FBgn0045977.html gene unnamed 16-Dec-15 2015_12 "visible,short lived,lethal,recessive" wing FBgn0266278 CR44963 http://flybase.net/reports/FBgn0266278.html non_protein_coding_gene CR44963 16-Dec-15 2015_12 FBgn0065853 l(2)SH0301 lethal (2) SH0301 http://flybase.net/reports/FBgn0065853.html gene l(2)SH2 0301 16-Dec-15 2015_12 "lethal,recessive" FBgn0036536 CG12713 http://flybase.net/reports/FBgn0036536.html protein_coding_gene IPR029404=Protein of unknown function with TPD sequence-motif CG12713 16-Dec-15 2015_12 ENSDARG00000070461(zgc:154061) ENSXETG00000012896(TTpA007f23.1) ENSMUSG00000040282(BC052040) "viable,visible" trichogen cell FBgn0082668 GS3132 GS3132 http://flybase.net/reports/FBgn0082668.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0266222 CR44917 http://flybase.net/reports/FBgn0266222.html non_protein_coding_gene CR44917 16-Dec-15 2015_12 FBgn0259633 B0319 http://flybase.net/reports/FBgn0259633.html gene 16-Dec-15 2015_12 visible 1st posterior cell FBgn0025174 l(2)38Db lethal (2) 38Db http://flybase.net/reports/FBgn0025174.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265823 CR44612 http://flybase.net/reports/FBgn0265823.html non_protein_coding_gene CR44612 16-Dec-15 2015_12 FBgn0045062 fs(1)100 female sterile (1) 100 http://flybase.net/reports/FBgn0045062.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "nurse cell,supernumerary,nurse cell ring canal" FBgn0032660 elfless elfless http://flybase.net/reports/FBgn0032660.html FBgn0063306 protein_coding_gene 0008270=zinc ion binding 0005634=nucleus "CG15150, BcDNA:AT24563, Elfless" "IPR001841=Zinc finger, RING-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG15150 16-Dec-15 2015_12 ENSXETG00000025752(rnf4) "viable,visible,eye color defective,lethal,fertile" "pigment cell,interommatidial bristle,eye" FBgn0024558 Dph5 Diphthamide methyltransferase http://flybase.net/reports/FBgn0024558.html "FBgn0027877, FBgn0051289" protein_coding_gene 0004164=diphthine synthase activity 0017183=peptidyl-diphthamide biosynthetic process from peptidyl-histidine 0005737=cytoplasm "BcDNA:LD12153, CG5275, BcDNA.LD12153, CG31289, l(3)L4910" "IPR004551=Diphthine synthase, IPR000878=Tetrapyrrole methylase, IPR014777=Tetrapyrrole methylase, subdomain 1, IPR014776=Tetrapyrrole methylase, subdomain 2" CG31289 16-Dec-15 2015_12 "ENSDARG00000011931(dph5),ENSDARG00000071466" YLR172C(DPH5) WBGene00007194(B0491.7) ENSXETG00000013255(Q6DEZ3_XENTR) ENSMUSG00000033554(Dph5) ENSG00000117543(DPH5) "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0030859 CG12990 http://flybase.net/reports/FBgn0030859.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG12990 16-Dec-15 2015_12 viable FBgn0004930 a(1)48 abnormal abdomen (1) 48 http://flybase.net/reports/FBgn0004930.html gene 16-Dec-15 2015_12 "visible,recessive,viable,good,fertile,maternal effect" "abdomen,adult abdomen" FBgn0267737 CR46068 http://flybase.net/reports/FBgn0267737.html non_protein_coding_gene Mgn1712 CR46068 16-Dec-15 2015_12 FBgn0050280 CG30280 http://flybase.net/reports/FBgn0050280.html "FBgn0034696, FBtr0071759, FBpp0071673" protein_coding_gene "AAF46801, FBpp0071673, CG6676, Fibrinogen-related protein" "IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR020837=Fibrinogen, conserved site, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1" CG30280 16-Dec-15 2015_12 ENSDARG00000060393(LOC567525) WBGene00020516(T15B7.1) "ENSXETG00000019734(FGL2),ENSXETG00000016174()" "ENSMUSG00000026841(Fibcd1),ENSMUSG00000026938(Fcna),ENSMUSG00000026835(Fcnb)" "ENSG00000160339(FCN2),ENSG00000142748(FCN3),ENSG00000085265(FCN1),ENSG00000166482(MFAP4)" "viable,visible" "chaeta,supernumerary" FBgn0030505 NFAT NFAT homolog http://flybase.net/reports/FBgn0030505.html "FBgn0043371, FBgn0043579" protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "2001020=regulation of response to DNA damage stimulus, 2000301=negative regulation of synaptic vesicle exocytosis, 0006355=regulation of transcription, DNA-templated, 0007476=imaginal disc-derived wing morphogenesis, 0046580=negative regulation of Ras protein signal transduction, 0009651=response to salt stress, 0006351=transcription, DNA-templated" 0005634=nucleus "Misexpression Suppressor of Ras 1, EP1335, CG11172, Nfat, NFAT, Drosophila TonEBP, NFAT5, dNFAT, Rel domain protein, MESR1, NF-AT5" "IPR014756=Immunoglobulin E-set, IPR008366=Nuclear factor of activated T cells (NFAT), IPR008967=p53-like transcription factor, DNA-binding, IPR011539=Rel homology domain (RHD), DNA-binding domain, IPR002909=IPT domain, IPR013783=Immunoglobulin-like fold" CG11172 16-Dec-15 2015_12 "ENSDARG00000014022,ENSDARG00000020872(nfat5)" ENSXETG00000017861(NFAT5) "viable,fertile,neuroanatomy defective,visible,neurophysiology defective,locomotor rhythm defective,lethal,recessive,partially lethal - majority live,wild-type,osmotic stress response defective" "intersegmental nerve,anterior fascicle & synapse,eye,wing vein,synapse,NMJ bouton,synapseD42,RP neuron,neuromuscular junctionRapGAP1-OK6,dorsocentral bristle,scutellar bristle,trichogen cell,neuromuscular junction,supernumerary,neuromuscular junctionD42,RP2 motor neuron,pupa,embryonic/larval anal pad" FBgn0264260 CG43760 http://flybase.net/reports/FBgn0264260.html protein_coding_gene CG43760 16-Dec-15 2015_12 FBgn0051532 CG31532 http://flybase.net/reports/FBgn0051532.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065223 l(2)SH2221 lethal (2) SH2221 http://flybase.net/reports/FBgn0065223.html gene l(2)SH2 2221 16-Dec-15 2015_12 "lethal,recessive" FBgn0266028 CR44793 http://flybase.net/reports/FBgn0266028.html non_protein_coding_gene CR44793 16-Dec-15 2015_12 FBgn0001796 l(1)Mb38 lethal (1) Mb38 http://flybase.net/reports/FBgn0001796.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" male genitalia FBgn0266239 CR44934 http://flybase.net/reports/FBgn0266239.html non_protein_coding_gene lincRNA.711 CR44934 16-Dec-15 2015_12 FBgn0024708 anon-83Ba anon-83Ba http://flybase.net/reports/FBgn0024708.html gene unnamed 16-Dec-15 2015_12 FBgn0050392 CG30392 http://flybase.net/reports/FBgn0050392.html "FBgn0034613, FBgn0045869" protein_coding_gene "0017089=glycolipid transporter activity, 0051861=glycolipid binding" 0046836=glycolipid transport 0005737=cytoplasm "CG10509, anon-WO0153538.80" IPR014830=Glycolipid transfer protein domain CG30392 16-Dec-15 2015_12 ENSDARG00000052537(gltpd1) WBGene00018632(tag-296) "ENSXETG00000021043(GLTPD2),ENSXETG00000011136(BC080926.1)" ENSMUSG00000029073(Gltpd1) "ENSG00000215792,ENSG00000220474" "viable,fertile" FBgn0061095 l(3)S009919 lethal (3) S009919 http://flybase.net/reports/FBgn0061095.html gene 0099/19 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000682 flrdE flight reduced E http://flybase.net/reports/FBgn0000682.html gene 0007629=flight behavior 16-Dec-15 2015_12 flight defective FBgn0040005 CG17883 http://flybase.net/reports/FBgn0040005.html "FBan0017883, FBgn0058289" protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity 0005783=endoplasmic reticulum CG40289 IPR000195=Rab-GTPase-TBC domain CG17883 16-Dec-15 2015_12 "ENSDARG00000032298(tbc1d20),ENSDARG00000039194(zgc:63863)" YFL027C(GYP8) WBGene00013196(tbc-20) "ENSXETG00000024010(TBC1D20),ENSXETG00000001457()" ENSMUSG00000027465(Tbc1d20) ENSG00000125875(TBC1D20) viable FBgn0259568 B1187 http://flybase.net/reports/FBgn0259568.html gene 16-Dec-15 2015_12 visible wing FBgn0065207 l(2)SH2275 lethal (2) SH2275 http://flybase.net/reports/FBgn0065207.html gene SH2275 16-Dec-15 2015_12 FBgn0266045 CR44810 http://flybase.net/reports/FBgn0266045.html non_protein_coding_gene lincRNA.388 CR44810 16-Dec-15 2015_12 FBgn0032366 CG14930 http://flybase.net/reports/FBgn0032366.html protein_coding_gene CG14930 16-Dec-15 2015_12 FBgn0038626 CG7691 http://flybase.net/reports/FBgn0038626.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG7691 16-Dec-15 2015_12 viable FBgn0014248 l(2)60Aa lethal (2) 60Aa http://flybase.net/reports/FBgn0014248.html gene 16-Dec-15 2015_12 lethal FBgn0022004 l(2)k09303 lethal (2) k09303 http://flybase.net/reports/FBgn0022004.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0050288 CG30288 http://flybase.net/reports/FBgn0050288.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG30288 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0052344 CG32344 http://flybase.net/reports/FBgn0052344.html FBgn0035130 protein_coding_gene "0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0004386=helicase activity, 0003723=RNA binding" 0022008=neurogenesis 0005634=nucleus "DmRH20, cg6994, CG6994" "IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR012541=DBP10CT, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG32344 16-Dec-15 2015_12 ENSDARG00000016015(ddx54) YDL031W(DBP10) WBGene00022378(Y94H6A.5) ENSXETG00000016410(ddx54) ENSMUSG00000029599(Ddx54) ENSG00000123064(DDX54) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0004653 Fs(1)10A Female sterile (1) 10A http://flybase.net/reports/FBgn0004653.html "FBgn0000731, FBgn0001188" gene 0001700=embryonic development via the syncytial blastoderm "haplo female sterile, hfs, unnamed" 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0259386 C38 http://flybase.net/reports/FBgn0259386.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0005749 l(1)TK302 lethal (1) TK302 http://flybase.net/reports/FBgn0005749.html gene l302 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0082353 HM304 HM304 http://flybase.net/reports/FBgn0082353.html gene 16-Dec-15 2015_12 FBgn0029992 Upf2 Upf2 http://flybase.net/reports/FBgn0029992.html protein_coding_gene 0003723=RNA binding "0016246=RNA interference, 0035195=gene silencing by miRNA, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, 0050808=synapse organization, 0007274=neuromuscular synaptic transmission" "CG2253, upf2, UPF2, smg-3, unnamed, up-frameshift suppressor 2" "IPR003890=MIF4G-like, type 3, IPR007193=Up-frameshift suppressor 2, IPR016021=MIF4G-like domain, IPR016024=Armadillo-type fold" CG2253 16-Dec-15 2015_12 YHR077C(NMD2) WBGene00004881(smg-3) ENSMUSG00000043241(Upf2) ENSG00000151461(UPF2) "lethal,viable,male sterile,fertile,lethal - all die before end of second instar larval stage,male limited,some die during second instar larval stage,germline clone,recessive,semi-fertile,neurophysiology defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during third instar larval stage" "adult tracheal system,somatic clone,eye,dorsal appendage,germline clone,follicle cell" FBgn0024701 bcd::upd1 bcd::os http://flybase.net/reports/FBgn0024701.html engineered_fusion_gene bcd::os 16-Dec-15 2015_12 FBgn0015842 Vm42A Vm42A http://flybase.net/reports/FBgn0015842.html gene T[[2]] 16-Dec-15 2015_12 FBgn0053098 CG33098 http://flybase.net/reports/FBgn0053098.html "FBgn0038031, FBgn0063747, FBgn0064842" protein_coding_gene 0005509=calcium ion binding 0016460=myosin II complex "BcDNA:AT09395, BcDNA:RH08915, CT39356, CG17756" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG33098 16-Dec-15 2015_12 viable FBgn0038968 CG12499 http://flybase.net/reports/FBgn0038968.html protein_coding_gene 0022008=neurogenesis "IPR021714=Nucleolar pre-ribosomal-associated protein 1, N-terminal" CG12499 16-Dec-15 2015_12 ENSDARG00000060308(LOC100333650) ENSMUSG00000039929(Urb1) ENSG00000142207(URB1) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0034129 CG15925 http://flybase.net/reports/FBgn0034129.html protein_coding_gene CG15925 16-Dec-15 2015_12 ENSDARG00000018593(zgc:77744) ENSXETG00000006648(PARP16) ENSMUSG00000032392(Parp16) ENSG00000138617(PARP16) viable FBgn0024275 UbxPRE Ultrabithorax Polycomb group response element http://flybase.net/reports/FBgn0024275.html regulatory_region "bxdPRE, PRE[[D]], PRE, BXD-PRE, Ubx-PRE, Polycomb Response Element, bithoraxoid Polycomb Response Element, Ubx PRE, bxd, Ubx(PRE), bxd PRE" 16-Dec-15 2015_12 FBgn0264530 l(3)ff17 http://flybase.net/reports/FBgn0264530.html gene 16-Dec-15 2015_12 lethal FBgn0013990 N52 N52 http://flybase.net/reports/FBgn0013990.html gene 16-Dec-15 2015_12 FBgn0004796 mln muslin http://flybase.net/reports/FBgn0004796.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0265968 Tfb5 TFB5 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0265968.html "FBgn0259719, FBgn0031669, FBgn0065482" protein_coding_gene 0000990=core RNA polymerase binding transcription factor activity "0001113=transcriptional open complex formation at RNA polymerase II promoter, 0009411=response to UV, 0006289=nucleotide-excision repair, 0001111=promoter clearance from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" "0000439=core TFIIH complex, 0005634=nucleus, 0005675=holo TFIIH complex" "CG14037, TTDA, TFB5 (uORF), lethal (2) SH1279, lincRNA.843, TFB5, CG42373, Dromel_CG31917_FBtr0079037_uORF, l(2)SH2 1279, uORF, l(2)SH1279, p8, Dmp8" IPR009400=TFIIH subunit TTDA/Tfb5 CG42373 16-Dec-15 2015_12 ENSDARG00000056099(gtf2h5) YDR079C-A(TFB5) WBGene00021904(Y55B1AL.2) ENSXETG00000023345(GTF2H5) ENSMUSG00000034345(Gtf2h5) ENSG00000185068(GTF2H5) FBgn0030886 CG12672 http://flybase.net/reports/FBgn0030886.html protein_coding_gene CG12672 16-Dec-15 2015_12 FBgn0025793 Su(var)505 Suppressor of variegation 505 http://flybase.net/reports/FBgn0025793.html gene Su-var(2)505 16-Dec-15 2015_12 FBgn0029821 CG4020 http://flybase.net/reports/FBgn0029821.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase, IPR016040=NAD(P)-binding domain" CG4020 16-Dec-15 2015_12 viable FBgn0013347 TfIIA-S Transcription-factor-IIA-S http://flybase.net/reports/FBgn0013347.html "FBgn0010326, FBgn0010327, FBgn0063013" protein_coding_gene "0001129=TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly, 0001128=RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0022008=neurogenesis" "0005634=nucleus, 0005672=transcription factor TFIIA complex" "BcDNA:RE44302, CG5163, TFIIA-S, dTFIIA-S, TFIIA, TF-IIAS, dTFIIA, F121, tfiia-s" "IPR003194=Transcription initiation factor IIA, gamma subunit, IPR015872=Transcription initiation factor IIA, gamma subunit, N-terminal, IPR009088=Transcription factor IIA, beta-barrel, IPR015871=Transcription initiation factor IIA, gamma subunit, C-terminal, IPR009083=Transcription factor IIA, helical" CG5163 16-Dec-15 2015_12 ENSDARG00000053685(zgc:110584) YKL058W(TOA2) WBGene00013736(Y111B2A.13) "ENSXETG00000022002(Q6DEQ4_XENTR),ENSXETG00000026944(Q6DEQ4_XENTR)" ENSMUSG00000033543(Gtf2a2) ENSG00000140307(GTF2A2) "partially lethal - majority die,visible,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,neuroanatomy defective,some die during pupal stage,female fertile" "eye,photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0262418 mir-6-3 mir-6-3 stem loop http://flybase.net/reports/FBgn0262418.html "FBgn0046817, FBgn0262259" miRNA_gene 0060548=negative regulation of cell death "CR42966, 6-3, miR-6, mir-6, Dme-miR-6, CR33039, dme-mir-6-3, mir-6-3, miR-6-3, miR6-3" CR42966 16-Dec-15 2015_12 " larval stage | first instar , embryonic stage " viable FBgn0039301 Nup37 Nucleoporin 37kD http://flybase.net/reports/FBgn0039301.html protein_coding_gene 0031080=nuclear pore outer ring "Nup37, CG11875" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG11875 16-Dec-15 2015_12 ENSDARG00000006710(nup37) ENSXETG00000002535(nup37) ENSMUSG00000035351(Nup37) ENSG00000075188(NUP37) "immune response defective,viable" FBgn0002384 l(3)93Cd lethal (3) 93Cd http://flybase.net/reports/FBgn0002384.html gene "er2, l(3)er2" 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0030840 p-cup presidents-cup http://flybase.net/reports/FBgn0030840.html protein_coding_gene "CG12993, p-cup, presidents-cup" CG12993 16-Dec-15 2015_12 viable FBgn0011332 l(3)j2C5 lethal (3) j2C5 http://flybase.net/reports/FBgn0011332.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259432 EP-J76 http://flybase.net/reports/FBgn0259432.html gene 16-Dec-15 2015_12 visible wing hair FBgn0040582 CG5791 http://flybase.net/reports/FBgn0040582.html FBgn0047035 protein_coding_gene 0005615=extracellular space BcDNA:RH16331 CG5791 16-Dec-15 2015_12 viable FBgn0000832 fs(1)M14 female sterile (1) M14 http://flybase.net/reports/FBgn0000832.html gene 16-Dec-15 2015_12 female sterile FBgn0053752 CG33752 http://flybase.net/reports/FBgn0053752.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33752 16-Dec-15 2015_12 FBgn0001361 l(1)1EFj lethal (1) 1EFj http://flybase.net/reports/FBgn0001361.html gene l(1)BA10 16-Dec-15 2015_12 lethal FBgn0264004 mir-5614 mir-5614 stem loop http://flybase.net/reports/FBgn0264004.html gene CR43747 16-Dec-15 2015_12 FBgn0052273 tRNA:CR32273 transfer RNA:CR32273 http://flybase.net/reports/FBgn0052273.html FBgn0060147 tRNA_gene 0033436=AUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:M:CAT:AE002584-a, chr3L.trna47-MetCAT, AE002584.trna19-MetCAT, CR32273" CR32273 16-Dec-15 2015_12 FBgn0002869 MtnB Metallothionein B http://flybase.net/reports/FBgn0002869.html protein_coding_gene "0005507=copper ion binding, 0046872=metal ion binding" "0055065=metal ion homeostasis, 0006875=cellular metal ion homeostasis, 0010038=response to metal ion" "metallothionein B, Mto, mtnB, metallothionein, MTN, MTO, DrosMto, MtnA, CG4312" "IPR000966=Metallothionein, family 5, Diptera" CG4312 16-Dec-15 2015_12 FBgn0060429 l(3)S126107 lethal (3) S126107 http://flybase.net/reports/FBgn0060429.html gene 1261/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011256 ms(2)30C male sterile (2) 30C http://flybase.net/reports/FBgn0011256.html gene 0007286=spermatid development ms(2)07822 16-Dec-15 2015_12 "male sterile,recessive" spermatid FBgn0054011 CG34011 http://flybase.net/reports/FBgn0054011.html FBgn0082902 protein_coding_gene "unnamed, BP1004" CG34011 16-Dec-15 2015_12 FBgn0004755 l(3)89Bh lethal (3) 89Bh http://flybase.net/reports/FBgn0004755.html gene 16-Dec-15 2015_12 lethal FBgn0040200 l(1)G0087 lethal (1) G0087 http://flybase.net/reports/FBgn0040200.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0267896 CR46184 http://flybase.net/reports/FBgn0267896.html pseudogene_attribute CG12717-related CR46184 16-Dec-15 2015_12 FBgn0040906 CG15579 http://flybase.net/reports/FBgn0040906.html protein_coding_gene CG15579 16-Dec-15 2015_12 viable FBgn0037350 CG2911 http://flybase.net/reports/FBgn0037350.html protein_coding_gene "IPR001623=DnaJ domain, IPR018253=DnaJ domain, conserved site, IPR007872=Zinc finger, DPH-type" CG2911 16-Dec-15 2015_12 ENSDARG00000023927(dnajc24) ENSG00000170946(DNAJC24) viable FBgn0000553 e(dpyv) enhancer of dumpy-vortex http://flybase.net/reports/FBgn0000553.html gene "vortex in chromosome 3, e(dp[v]), vo-3" 16-Dec-15 2015_12 wild-type FBgn0058198 CG40198 http://flybase.net/reports/FBgn0058198.html "FBgn0062452, FBan0040198" protein_coding_gene BcDNA:RE21703 CG40198 16-Dec-15 2015_12 FBgn0086374 EP893 http://flybase.net/reports/FBgn0086374.html gene 16-Dec-15 2015_12 FBgn0038356 CG12784 http://flybase.net/reports/FBgn0038356.html protein_coding_gene CG12784 16-Dec-15 2015_12 viable FBgn0003054 Pec Pupilla eccentrica http://flybase.net/reports/FBgn0003054.html gene 16-Dec-15 2015_12 "visible,heat sensitive,eye color defective" "eye,heat sensitive,ocellus" FBgn0261002 Omar Omar http://flybase.net/reports/FBgn0261002.html gene "AGAR-82, AGAR-83" 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0060947 l(3)S037906 lethal (3) S037906 http://flybase.net/reports/FBgn0060947.html gene 0379/06 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053757 CG33757 http://flybase.net/reports/FBgn0053757.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33757 16-Dec-15 2015_12 FBgn0037142 CG14562 http://flybase.net/reports/FBgn0037142.html FBgn0044628 protein_coding_gene 0031084=BLOC-2 complex "NP_649372, HPS3, anon-WO0140519.241" "IPR029437=Hermansky-Pudlak syndrome 3 protein, N-terminal domain, IPR028167=Hermansky-Pudlak syndrome 3, central region" CG14562 16-Dec-15 2015_12 ENSMUSG00000027615(Hps3) viable FBgn0001837 l(1)ts958 lethal (1) ts958 http://flybase.net/reports/FBgn0001837.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0029025 l(3)77ABg lethal (3) 77ABg http://flybase.net/reports/FBgn0029025.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0000747 fs(1)A330 female sterile (1) A330 http://flybase.net/reports/FBgn0000747.html gene 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,recessive,female sterile" embryo FBgn0031631 CG3225 http://flybase.net/reports/FBgn0031631.html protein_coding_gene "0003676=nucleic acid binding, 0004386=helicase activity, 0004004=ATP-dependent RNA helicase activity, 0003724=RNA helicase activity, 0005524=ATP binding" "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome" cg3225 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007502=Helicase-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011709=Domain of unknown function DUF1605, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650=Helicase, C-terminal" CG3225 16-Dec-15 2015_12 WBGene00022056(Y67D2.6) ENSXETG00000012145(DHX35) ENSMUSG00000027655(Dhx35) ENSG00000101452(DHX35) "viable,visible" trichogen cell FBgn0033326 CG14743 http://flybase.net/reports/FBgn0033326.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane IPR004837=Sodium/calcium exchanger membrane region CG14743 16-Dec-15 2015_12 "WBGene00003574(ncx-9),WBGene00003573(ncx-8),WBGene00003575(ncx-10),WBGene00003571(ncx-6)" ENSMUSG00000032754(Slc24a6) ENSG00000089060(SLC24A6) viable FBgn0002899 mus301 mutagen-sensitive 301 http://flybase.net/reports/FBgn0002899.html "FBgn0003481, FBgn0035843, FBgn0062073" protein_coding_gene "0005524=ATP binding, 0003676=nucleic acid binding, 0004386=helicase activity" "0009994=oocyte differentiation, 0009951=polarity specification of dorsal/ventral axis, 0016321=female meiosis chromosome segregation, 0008298=intracellular mRNA localization, 0030717=karyosome formation, 0006417=regulation of translation, 0007294=germarium-derived oocyte fate determination, 0009949=polarity specification of anterior/posterior axis, 0048477=oogenesis" "0030532=small nuclear ribonucleoprotein complex, 0005682=U5 snRNP" "spindel, spn-C, spnC, mus(3)301, SpnC, Mus301, anon-WO0118547.354, spindle C, spindle-C, cg7972, CG7972" "IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG7972 16-Dec-15 2015_12 ENSDARG00000063638 WBGene00021905(hel-308) ENSXETG00000001831(HELQ) ENSMUSG00000035266(Helq) ENSG00000163312(HELQ) "chemical sensitive,recessive,viable,fertile,radiation sensitive" "chorion | maternal effect,karyosome,egg,maternal effect,oocyte nucleus,oocyte,egg chamber,dorsal appendage,synaptonemal complex,germline cyst,dorsal,nurse cell" FBgn0041585 olf186-F olf186-F http://flybase.net/reports/FBgn0041585.html "FBgn0021911, FBgn0034280, FBgn0064926" protein_coding_gene "0015279=store-operated calcium channel activity, 0004252=serine-type endopeptidase activity" "0002115=store-operated calcium entry, 0051928=positive regulation of calcium ion transport, 0007399=nervous system development, 0006508=proteolysis, 0051533=positive regulation of NFAT protein import into nucleus" 0016021=integral component of membrane "lethal (2) k11505, dOrai1, l(2)k11505, BcDNA:LD03241, CRACM1, CG11430, Olf186-F, dorai, CRAC modulator 1, Orai, dOrai, SPH206" IPR012446=Calcium release-activated calcium channel protein CG11430 16-Dec-15 2015_12 WBGene00015648(orai-1) "ENSMUSG00000043964(Orai3),ENSMUSG00000049686(Orai1),ENSMUSG00000039747(Orai2)" "ENSG00000175938(ORAI3),ENSG00000182500(ORAI1),ENSG00000160991(ORAI2)" "lethal,recessive,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" dorsal medial muscle FBgn0259845 Su(Ste):CR42414 Su(Ste):CR42414 http://flybase.net/reports/FBgn0259845.html non_protein_coding_gene "RR41763, CR42414" CR42414 16-Dec-15 2015_12 FBgn0265484 BG02466 http://flybase.net/reports/FBgn0265484.html gene 16-Dec-15 2015_12 "sleep defective,male limited" FBgn0065631 l(2)SH0782 lethal (2) SH0782 http://flybase.net/reports/FBgn0065631.html gene l(2)SH2 0782 16-Dec-15 2015_12 "lethal,recessive" FBgn0015432 l(1)4ACa lethal (1) 4ACa http://flybase.net/reports/FBgn0015432.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004094 l(2)60Db lethal (2) 60Db http://flybase.net/reports/FBgn0004094.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024205 ol3 oocyte localisation 3 http://flybase.net/reports/FBgn0024205.html gene 16-Dec-15 2015_12 FBgn0040143 l(1)G0487 lethal (1) G0487 http://flybase.net/reports/FBgn0040143.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0014037 Su(Tpl) Su(Tpl) http://flybase.net/reports/FBgn0014037.html "FBgn0016733, FBgn0025923, FBgn0028080, FBgn0028245, FBgn0028435, FBgn0036914, FBgn0052216, FBgn0052217" protein_coding_gene 0003682=chromatin binding "0042795=snRNA transcription from RNA polymerase II promoter, 0043620=regulation of DNA-templated transcription in response to stress, 0006368=transcription elongation from RNA polymerase II promoter, 0048190=wing disc dorsal/ventral pattern formation" "0005700=polytene chromosome, 0008023=transcription elongation factor complex, 0005634=nucleus" "l(3)76BDs, dELL, Ell, elongation factor RNA polymerase II, l (3)76BD, CR32216, eleven-nineteen lysine-rich leukemia, SS3-4, l(3)S085401, CG32217, Su(Tpl)/, SY3-1, l(3)S000606, ELL, Suppressor of GMR-sina 3-4, 0854/01, Suppressor of Triplolethal, SR3-4A, CG8037" "IPR019464=RNA polymerase II elongation factor ELL, N-terminal, IPR010844=Occludin homology domain, IPR031176=ELL/occludin family" CG32217 16-Dec-15 2015_12 "ENSDARG00000006251(ell2),ENSDARG00000000568(ell),ENSDARG00000038121,ENSDARG00000069258" "ENSXETG00000027613(ELL3),ENSXETG00000013296(ell2)" "ENSMUSG00000001542(Ell2),ENSMUSG00000070002(Ell)" "ENSG00000118985(ELL2),ENSG00000105656(ELL)" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" "eye,somatic clone,eye photoreceptor cell,pigment cell,embryonic metathoracic segment,embryonic mesothoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 4,embryonic abdominal segment 3,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic head,embryonic abdominal segment 8,macrochaeta,tormogen cell" DRSC26497 EK 0.013798626 1.044145927 1.038951321 1.654643023 -0.213354908 2.380758267 FBgn0033047 CG7882 http://flybase.net/reports/FBgn0033047.html protein_coding_gene 0005355=glucose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR003663=Sugar/inositol transporter, IPR020846=Major facilitator superfamily domain" CG7882 16-Dec-15 2015_12 YNL318C(HXT14) "viable,fertile" FBgn0014297 l(3)64Bh lethal (3) 64Bh http://flybase.net/reports/FBgn0014297.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259319 C877 http://flybase.net/reports/FBgn0259319.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0005383 Gtd Glucose tasting-defective http://flybase.net/reports/FBgn0005383.html gene GT-1 16-Dec-15 2015_12 "taste perception defective,dominant,partially" FBgn0034270 CG6401 http://flybase.net/reports/FBgn0034270.html protein_coding_gene 0017176=phosphatidylinositol N-acetylglucosaminyltransferase activity 0006506=GPI anchor biosynthetic process 0030176=integral component of endoplasmic reticulum membrane Dm*AAF57802/5-442 "IPR001296=Glycosyl transferase, family 1, IPR013234=PIGA, GPI anchor biosynthesis" CG6401 16-Dec-15 2015_12 ENSDARG00000041040(piga) YPL175W(SPT14) WBGene00008431(D2085.6) ENSXETG00000008525(PIGA) ENSMUSG00000031381(Piga) ENSG00000165195(PIGA) "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266066 CR44819 http://flybase.net/reports/FBgn0266066.html non_protein_coding_gene CR44819 16-Dec-15 2015_12 FBgn0005666 bt bent http://flybase.net/reports/FBgn0005666.html "FBgn0000232, FBgn0004518, FBgn0004630, FBgn0005627, FBgn0039921, FBgn0052019" protein_coding_gene "0004687=myosin light chain kinase activity, 0008307=structural constituent of muscle, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005200=structural constituent of cytoskeleton, 0005524=ATP binding" "0045214=sarcomere organization, 0006468=protein phosphorylation, 0071689=muscle thin filament assembly, 0007498=mesoderm development" "0030018=Z disc, 0030017=sarcomere, 0031674=I band" "twitchin, l(2)23, Projectin myosin light chain kinase, CG1479, unnamed, CG32019, l(4)37, lethal(4) Powell, Tennessee-2, 39c-18, l(4)2, bent, Prj, Bt, Projectin, CG10285, myosin LCK, CT3598, PROJECTIN, projectin, l(4)23, l(2)2, l(4)38, C-protein, l(4)21, CT8086, l(4)PT-2, titin, l(4)102CDa" "IPR013783=Immunoglobulin-like fold, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR007110=Immunoglobulin-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG32019 16-Dec-15 2015_12 "ENSDARG00000028213,ENSDARG00000000563(ttnb)" WBGene00006759(unc-22) ENSG00000154358(OBSCN) " larval stage , adult stage , pupal stage && adult stage " " larval muscle system

, adult muscle system

, synchronous muscle

, indirect flight muscle

" " adult stage , embryonic stage | late , larval stage--adult stage " " indirect flight muscle

, tubular muscle

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage" "wing,leg,Z discMef2.PR" FBgn0041235 Gr59c Gustatory receptor 59c http://flybase.net/reports/FBgn0041235.html "FBgn0034823, FBgn0050186" protein_coding_gene "0008527=taste receptor activity, 0033038=bitter taste receptor activity, 0033041=sweet taste receptor activity" "0050909=sensory perception of taste, 0050916=sensory perception of sweet taste, 0050913=sensory perception of bitter taste" 0016021=integral component of membrane "Gustatory receptor 59D.2, CG30186, CG13543, GR59D.2, 59D2, 59D.2, Gr59D2, GR59c" IPR013604=7TM chemoreceptor CG30186 16-Dec-15 2015_12 "neurophysiology defective,taste perception defective,partially lethal - majority die,some die during pupal stage" "I-type sensilla I8,I-type sensilla I9,I-type sensilla I10,S-type sensilla S5,S-type sensilla S6,I-type sensilla I5" FBgn0003223 rdt reduced thorax http://flybase.net/reports/FBgn0003223.html gene 16-Dec-15 2015_12 "viable,male,poor,male sterile,visible" "wing,adult abdomen,adult head,adult thorax" FBgn0260960 Baldspot Baldspot http://flybase.net/reports/FBgn0260960.html "FBgn0036650, FBgn0010775, FBgn0011458, FBgn0013626, FBgn0045248, FBgn0045250, FBgn0027947" protein_coding_gene 0009922=fatty acid elongase activity "0042759=long-chain fatty acid biosynthetic process, 0030497=fatty acid elongation, 0007283=spermatogenesis" "0030176=integral component of endoplasmic reticulum membrane, 0016021=integral component of membrane" "l(3)04106, CG3971, NEST:bs18g10, blp, NEST:bs18f10, l(3)neo21, neighbor of abl, l(3)01895, l(3)02281, baldspot, noa, CG 3971, l(3)neo22" IPR002076=ELO family CG3971 16-Dec-15 2015_12 "ENSDARG00000004402(elovl6),ENSDARG00000055946,ENSDARG00000038639(elovl6l),ENSDARG00000012632(zgc:92749)" "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" WBGene00001241(elo-3) ENSXETG00000010017() ENSMUSG00000041220(Elovl6) ENSG00000170522(ELOVL6) FBgn0005279 M(2)p Minute (2) p http://flybase.net/reports/FBgn0005279.html gene M[[p]] 16-Dec-15 2015_12 FBgn0010531 Ccs Copper chaperone for superoxide dismutase http://flybase.net/reports/FBgn0010531.html "FBgn0025541, FBgn0033487" protein_coding_gene "0016532=superoxide dismutase copper chaperone activity, 0008270=zinc ion binding, 0004784=superoxide dismutase activity" "0050821=protein stabilization, 0015680=intracellular copper ion transport, 0006979=response to oxidative stress, 0055114=oxidation-reduction process, 0019430=removal of superoxide radicals, 0008340=determination of adult lifespan" "0005743=mitochondrial inner membrane, 0005634=nucleus, 0005737=cytoplasm, 0005829=cytosol, 0005777=peroxisome" "dCCS, DmCCS, Cu-chaperone for superoxide dismutase, Ccs, CCD, l(2)03221, anon-EST:Posey231, CG-17753, CCS, CG17753" "IPR001424=Superoxide dismutase, copper/zinc binding domain, IPR018152=Superoxide dismutase, copper/zinc, binding site" CG17753 16-Dec-15 2015_12 ENSDARG00000052969(zgc:112427) ENSXETG00000011424(ccs) ENSMUSG00000034108(Ccs) ENSG00000173992(CCS) "short lived,chemical sensitive,recessive,lethal,viable" DRSC06692 I 1.684213878 0.155753272 0.605814959 0.187692758 -0.352762659 -0.213409319 FBgn0013461 fs(3)neo27 fs(3)neo27 http://flybase.net/reports/FBgn0013461.html gene unnamed 16-Dec-15 2015_12 "female sterile,lethal,maternal effect" FBgn0261808 cu curled http://flybase.net/reports/FBgn0261808.html "FBgn0000387, FBgn0037872, FBgn0037871, FBgn0051299" protein_coding_gene "0009416=response to light stimulus, 0045475=locomotor rhythm, 0000289=nuclear-transcribed mRNA poly(A) tail shortening" "0005737=cytoplasm, 0030014=CCR4-NOT complex, 0005811=lipid particle" "nocturin, noc, Dnocturnin, Nocturnin, CG4796, nocturnin, CG31299, no(cu), noct, CG4782, no" IPR005135=Endonuclease/exonuclease/phosphatase CG31299 16-Dec-15 2015_12 ENSXETG00000016899(ccrn4l) FBgn0032938 CG8671 http://flybase.net/reports/FBgn0032938.html FBgn0062186 protein_coding_gene 0033227=dsRNA transport anon-WO0118547.182 IPR019448=EEIG1/EHBP1 N-terminal domain CG8671 16-Dec-15 2015_12 "ENSDARG00000053104(fam102ba),ENSDARG00000002333(fam102bb),ENSDARG00000016866(zgc:152955),ENSDARG00000025846" "ENSXETG00000009948(FAM102B),ENSXETG00000023071(FAM102A)" "ENSMUSG00000040339(Fam102b),ENSMUSG00000039157(Fam102a)" "ENSG00000162636(FAM102B),ENSG00000167106(FAM102A)" FBgn0005046 E(var)43A Enhancer of variegation 43A http://flybase.net/reports/FBgn0005046.html gene 16-Dec-15 2015_12 FBgn0024257 acd(2)5N29 auditory courtship defective 5N29 http://flybase.net/reports/FBgn0024257.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0053294 CR33294 http://flybase.net/reports/FBgn0053294.html "FBan0033294, FBgn0082879" pseudogene_attribute "CG33294, unnamed, BP1027" CR33294 16-Dec-15 2015_12 FBgn0033466 Pal1 Peptidyl-ë±-hydroxyglycine-ë±-amidating lyase 1 http://flybase.net/reports/FBgn0033466.html FBgn0045949 protein_coding_gene "0004504=peptidylglycine monooxygenase activity, 0004598=peptidylamidoglycolate lyase activity, 0005507=copper ion binding" "0055114=oxidation-reduction process, 0006518=peptide metabolic process" "0016020=membrane, 0043025=neuronal cell body" "dPAL1, anon-WO0149856.3, DPAL1, PAL1, CG12130" "IPR001258=NHL repeat, IPR011042=Six-bladed beta-propeller, TolB-like, IPR000720=Peptidyl-glycine alpha-amidating monooxygenase, IPR013017=NHL repeat, subgroup" CG12130 16-Dec-15 2015_12 ENSDARG00000069714 WBGene00017671(F21F3.1) ENSXETG00000023863(PAM) ENSMUSG00000042997(Nhlrc3) viable FBgn0061082 l(3)S012613b lethal (3) S012613b http://flybase.net/reports/FBgn0061082.html gene 0126/13 16-Dec-15 2015_12 lethal FBgn0001098 Gdh Glutamate dehydrogenase http://flybase.net/reports/FBgn0001098.html protein_coding_gene "0004353=glutamate dehydrogenase [NAD(P)+] activity, 0004352=glutamate dehydrogenase (NAD+) activity, 0042802=identical protein binding" "0006536=glutamate metabolic process, 0006116=NADH oxidation, 0019551=glutamate catabolic process to 2-oxoglutarate, 0009060=aerobic respiration, 0046693=sperm storage" "0005759=mitochondrial matrix, 0005829=cytosol, 0005737=cytoplasm, 0005739=mitochondrion" "GLU-D, CG5320, NAD-dependent glutamate dehydrogenase, Glud, DHE3, GLUD pre-mRNA, GLUD, gdh, GDH, GLUTAMATE DEHYDROGENASE, glutamate dehydrogenase" "IPR014362=Glutamate dehydrogenase, IPR006096=Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal, IPR006095=Glutamate/phenylalanine/leucine/valine dehydrogenase, IPR016040=NAD(P)-binding domain, IPR006097=Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain" CG5320 16-Dec-15 2015_12 "ENSDARG00000008816(glud1a),ENSDARG00000002414(glud1b)" "YAL062W(GDH3),YOR375C(GDH1)" WBGene00014095(ZK829.4) ENSXETG00000008151() ENSMUSG00000021794(Glud1) "ENSG00000148672(GLUD1),ENSG00000182890(GLUD2)" "viable,fertile,electrophoretic variant" FBgn0026216 l(3)06948a lethal (3) 06948a http://flybase.net/reports/FBgn0026216.html gene l(3)06948 16-Dec-15 2015_12 lethal FBgn0035112 CG13877 http://flybase.net/reports/FBgn0035112.html protein_coding_gene CG13877 16-Dec-15 2015_12 FBgn0031894 CG4496 http://flybase.net/reports/FBgn0031894.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG4496 16-Dec-15 2015_12 viable FBgn0039829 CG15561 http://flybase.net/reports/FBgn0039829.html protein_coding_gene 0003676=nucleic acid binding IPR000467=G-patch domain CG15561 16-Dec-15 2015_12 ENSDARG00000061624(LOC555692) YMR269W(TMA23) ENSXETG00000020397(TGas105i04.1) ENSMUSG00000028069(Gpatch4) ENSG00000160818(GPATCH4) "viable,fertile" FBgn0032282 CG7299 http://flybase.net/reports/FBgn0032282.html FBgn0063048 protein_coding_gene "BcDNA:RE24635, CT22515" CG7299 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0010830 l(3)04053 lethal (3) 04053 http://flybase.net/reports/FBgn0010830.html "FBgn0011407, FBgn0037187" protein_coding_gene "l(3)j8B2, CG11238" CG11238 16-Dec-15 2015_12 "viable,fertile,lethal,recessive,partially lethal - majority die" FBgn0030981 CG14191 http://flybase.net/reports/FBgn0030981.html FBgn0061411 protein_coding_gene BcDNA:RE09269 CG14191 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0266044 CR44809 http://flybase.net/reports/FBgn0266044.html non_protein_coding_gene lincRNA.230 CR44809 16-Dec-15 2015_12 FBgn0263667 Lpt Lost PHDs of trr http://flybase.net/reports/FBgn0263667.html "FBgn0034926, FBgn0259119" protein_coding_gene "0008270=zinc ion binding, 0042393=histone binding, 0030374=ligand-dependent nuclear receptor transcription coactivator activity, 0003682=chromatin binding" "0018990=ecdysis, chitin-based cuticle, 0008586=imaginal disc-derived wing vein morphogenesis, 0007474=imaginal disc-derived wing vein specification, 0051568=histone H3-K4 methylation, 0006909=phagocytosis, 1900114=positive regulation of histone H3-K9 trimethylation, 0071390=cellular response to ecdysone, 0035556=intracellular signal transduction, 0035076=ecdysone receptor-mediated signaling pathway, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0044666=MLL3/4 complex, 0005700=polytene chromosome, 0000790=nuclear chromatin, 0008230=ecdysone receptor holocomplex" "Cmi, Lost PHDs of Trr, lost PHD finger of Trr, cmi, cara mitad, lost PHDs of Trr, Cara Mitad, CG5591, LPT, cg5591" "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR009071=High mobility group box domain, IPR001841=Zinc finger, RING-type, IPR019787=Zinc finger, PHD-finger" CG5591 16-Dec-15 2015_12 "ENSXETG00000009730(MLL3),ENSXETG00000011176(MLL2)" "ENSMUSG00000038056(Mll3),ENSMUSG00000048154(Mll2)" DRSC04515 EK 0.245977331 0.092606531 -2.608174849 1.215302843 -0.031328518 1.740426086 FBgn0011447 l(3)neo3 lethal (3) neo3 http://flybase.net/reports/FBgn0011447.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043536 Obp57d Odorant-binding protein 57d http://flybase.net/reports/FBgn0043536.html "FBgn0050150, FBgn0063474" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "anon-AE003791.1, Obp-g, Obp57e, unnamed, OBP57d, Obp57d, 57d, CG30150, DmelObp57d, Dmel\Obp57d" IPR006170=Pheromone/general odorant binding protein CG30150 16-Dec-15 2015_12 viable FBgn0004610 NaDh ë_ N-acetyl D-hexosaminidase http://flybase.net/reports/FBgn0004610.html gene 0004563=beta-N-acetylhexosaminidase activity 0006036=cuticle chitin catabolic process beta-D-hexosaminidaseII 16-Dec-15 2015_12 FBgn0000554 ee extra eye http://flybase.net/reports/FBgn0000554.html gene 0035214=eye-antennal disc development 16-Dec-15 2015_12 "visible,heat sensitive" "adult head,eye,ectopic,ocellus,antenna,rhabdomere" FBgn0020817 l(3)98Dm lethal (3) 98Dm http://flybase.net/reports/FBgn0020817.html gene M217 16-Dec-15 2015_12 "lethal,recessive" FBgn0261613 Oaz O/E-associated zinc finger protein http://flybase.net/reports/FBgn0261613.html "FBgn0033939, FBgn0033937, FBgn0033938" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0035277=spiracle morphogenesis, open tracheal system, 0045893=positive regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "Dm_2R:42259, CG42702, CG17388, CG17389, dmOAZ, oaz, CG17390" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG42702 16-Dec-15 2015_12 "ENSDARG00000059707(si:ch211-216l23.1),ENSDARG00000005353" "WBGene00005009(spr-4),WBGene00016189(C28G1.4)" ENSXETG00000002339(ZNF423) "ENSMUSG00000045333(Zfp423),ENSMUSG00000024420(Zfp521)" "ENSG00000102935(ZNF423),ENSG00000198795(ZNF521)" DRSC06666 I -0.072935112 -2.181505592 -0.372561481 -1.151943864 -0.802968185 -0.076064264 FBgn0266621 CR45128 http://flybase.net/reports/FBgn0266621.html non_protein_coding_gene CR45128 16-Dec-15 2015_12 FBgn0267237 CR45677 http://flybase.net/reports/FBgn0267237.html non_protein_coding_gene CR45677 16-Dec-15 2015_12 FBgn0002775 msl-3 male-specific lethal 3 http://flybase.net/reports/FBgn0002775.html protein_coding_gene "0003682=chromatin binding, 0003723=RNA binding, 0003729=mRNA binding, 0035064=methylated histone binding" "0009047=dosage compensation by hyperactivation of X chromosome, 0035206=regulation of hemocyte proliferation, 0031936=negative regulation of chromatin silencing, 0007549=dosage compensation" "0000805=X chromosome, 0016456=X chromosome located dosage compensation complex, transcription activating, 0010369=chromocenter, 0005634=nucleus, 0005694=chromosome, 0072487=MSL complex, 0005700=polytene chromosome, 0000228=nuclear chromosome" "CG8631, MSL3, mls3, Msl3, male specifc lethal, male specific lethal 3, gene 2, male sex lethal-3, DmMsl-3, MSL, mle3, male sex lethal 3, msl, msl3, MSL3_DROME, MSL-3, Msl 1-3, mle(3)132" "IPR008676=MRG, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like, IPR026541=MRG domain" CG8631 16-Dec-15 2015_12 "ENSMUSG00000031358(Msl3),ENSMUSG00000047669" ENSG00000005302(MSL3) " larval stage | female , larval stage | male " "developmental rate defective,male sterile,wild-type,lethal,male,recessive,lethal - all die before end of larval stage,some die during larval stage,non-suppressor of variegation,dominant,suppressor of variegation,visible,male limited,somatic clone,viable" "wing,eye,male limited,somatic clone" FBgn0265767 zyd zydeco http://flybase.net/reports/FBgn0265767.html "FBgn0243503, FBgn0025689, FBgn0058147, FBan0002893, FBgn0040030" protein_coding_gene "0008273=calcium, potassium:sodium antiporter activity" 0055085=transmembrane transport "0005886=plasma membrane, 0016021=integral component of membrane" "CG2893, CG40147, BEST:CK02262, zydeco, CK02262" "IPR004837=Sodium/calcium exchanger membrane region, IPR004481=Sodium/potassium/calcium exchanger" CG2893 16-Dec-15 2015_12 YDL206W() "ENSMUSG00000041771(Slc24a4),ENSMUSG00000063873(Slc24a3)" "ENSG00000140090(SLC24A4),ENSG00000185052(SLC24A3)" "bang sensitive,viable,behavior defective,recessive,heat sensitive,neurophysiology defective,partially lethal - majority die" FBgn0029813 CG15766 http://flybase.net/reports/FBgn0029813.html protein_coding_gene 0008080=N-acetyltransferase activity "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG15766 16-Dec-15 2015_12 "viable,fertile" FBgn0265669 CG44476 http://flybase.net/reports/FBgn0265669.html protein_coding_gene lincRNA.179 CG44476 16-Dec-15 2015_12 FBgn0065651 l(2)SH0733 lethal (2) SH0733 http://flybase.net/reports/FBgn0065651.html gene l(2)SH2 0733 16-Dec-15 2015_12 "lethal,recessive" FBgn0259823 CG42404 http://flybase.net/reports/FBgn0259823.html "CG34128, CG4285, FBgn0083964, FBgn0038310, FBgn0051154, FBgn0062882" protein_coding_gene "CG34128, BcDNA:SD12744, CG31154, CG4285, lincRNA.S6902" IPR001007=VWFC domain CG42404 16-Dec-15 2015_12 FBgn0061159 l(1)7Fh lethal (1) 7Fh http://flybase.net/reports/FBgn0061159.html gene 16-Dec-15 2015_12 "lethal,recessive" "melanotic mass,melanotic mass & salivary gland,melanotic mass & tracheal system" FBgn0033569 CG12942 http://flybase.net/reports/FBgn0033569.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG12942 16-Dec-15 2015_12 viable FBgn0011870 tRNA:G3:56EFb transfer RNA:gly3:56EFb http://flybase.net/reports/FBgn0011870.html "FBgn0003782, FBgn0050138, FBgn0060215" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033462=GGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:gly3:56EFb, tRNA[Gly-GCC], chr2R.trna43-GlyGCC, CR30138, tRNA:G:GCC:AE002787-d, AE002787.trna59-GlyGCC" CR30138 16-Dec-15 2015_12 FBgn0040901 CG13757 http://flybase.net/reports/FBgn0040901.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001710 l(1)ESHS31 lethal (1) ESHS31 http://flybase.net/reports/FBgn0001710.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027512 CG10254 http://flybase.net/reports/FBgn0027512.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0006513=protein monoubiquitination 0005737=cytoplasm BcDNA:LD22087 "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG10254 16-Dec-15 2015_12 ENSMUSG00000020802(Ube2o) ENSG00000175931(UBE2O) viable FBgn0016974 swaë¬ swallow pseudogene http://flybase.net/reports/FBgn0016974.html FBgn0052747 pseudogene_attribute "CR32747, swaPsi, Swallow Psi, unnamed, CG3429" CR32747 16-Dec-15 2015_12 FBgn0032119 CG3769 http://flybase.net/reports/FBgn0032119.html protein_coding_gene "IPR022780=Dynein family light intermediate chain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3769 16-Dec-15 2015_12 ENSDARG00000039770(dync2li1) WBGene00006960(xbx-1) ENSXETG00000009287(DYNC2LI1) ENSMUSG00000024253(Dync2li1) ENSG00000138036(DYNC2LI1) viable FBgn0016881 l(2)39DEf lethal (2) 39DEf http://flybase.net/reports/FBgn0016881.html gene I4 16-Dec-15 2015_12 lethal FBgn0024357 ES3-1 Enhancer of GMR-sina 3-1 http://flybase.net/reports/FBgn0024357.html gene 16-Dec-15 2015_12 FBgn0082935 snoRNA:Me28S-G1083a snoRNA:Me28S-G1083a http://flybase.net/reports/FBgn0082935.html snoRNA_gene 0030562=rRNA 2'-O-ribose methylation guide activity 0000451=rRNA 2'-O-methylation 0005730=nucleolus "DmSnR60, CR34562, Me28S-Gm1083a, DmSnR60a, Me28S-G1083a(DmSnR60)" CR34562 16-Dec-15 2015_12 FBgn0050458 CG30458 http://flybase.net/reports/FBgn0050458.html FBgn0034203 protein_coding_gene CG17288 IPR004011=GYR motif CG30458 16-Dec-15 2015_12 viable FBgn0265421 CR44333 http://flybase.net/reports/FBgn0265421.html non_protein_coding_gene CR44333 16-Dec-15 2015_12 FBgn0035168 cep290 cep290 http://flybase.net/reports/FBgn0035168.html protein_coding_gene "0042384=cilium assembly, 0042048=olfactory behavior" "0097542=ciliary tip, 0072372=primary cilium" "CG13889, Q9W0M1_DROME" CG13889 16-Dec-15 2015_12 ENSG00000198707(CEP290) "viable,smell perception defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031000 Muc18B Mucin 18B http://flybase.net/reports/FBgn0031000.html protein_coding_gene "0005201=extracellular matrix structural constituent, 0008061=chitin binding" 0006030=chitin metabolic process "0031012=extracellular matrix, 0005576=extracellular region" "Muc18B, CG7876" IPR002557=Chitin binding domain CG7876 16-Dec-15 2015_12 FBgn0082635 S(CycEJP)2.10 S(CycEJP)2.10 http://flybase.net/reports/FBgn0082635.html gene Complementation group 2.10 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0046843 ird25 immune response deficient 25 http://flybase.net/reports/FBgn0046843.html gene 0006959=humoral immune response 16-Dec-15 2015_12 "lethal,recessive,immune response defective" FBgn0259273 EP-471 http://flybase.net/reports/FBgn0259273.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta,ectopic" FBgn0259283 C544 http://flybase.net/reports/FBgn0259283.html gene 16-Dec-15 2015_12 visible wing FBgn0266068 CR44821 http://flybase.net/reports/FBgn0266068.html non_protein_coding_gene CR44821 16-Dec-15 2015_12 FBgn0037105 S1P S1P http://flybase.net/reports/FBgn0037105.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006629=lipid metabolic process, 0006508=proteolysis, 0035103=sterol regulatory element binding protein cleavage" 0005794=Golgi apparatus "CG7169, dS1P" "IPR015500=Peptidase S8, subtilisin-related, IPR023828=Peptidase S8, subtilisin, Ser-active site, IPR000209=Peptidase S8/S53 domain, IPR022398=Peptidase S8, subtilisin, His-active site" CG7169 16-Dec-15 2015_12 ENSDARG00000014634(mbtps1) ENSXETG00000021709(MBTPS1) ENSMUSG00000031835(Mbtps1) ENSG00000140943(MBTPS1) viable FBgn0061067 l(3)S020004b lethal (3) S020004b http://flybase.net/reports/FBgn0061067.html gene 0200/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0036834 CG6836 http://flybase.net/reports/FBgn0036834.html protein_coding_gene 0005215=transporter activity 0006810=transport 0016021=integral component of membrane IPR005178=Organic solute transporter subunit alpha/Transmembrane protein 184 CG6836 16-Dec-15 2015_12 viable FBgn0051588 tRNA:CR31588 transfer RNA:CR31588 http://flybase.net/reports/FBgn0051588.html FBgn0060233 tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31588, chr3R.trna11-PheGAA, AE002708.trna5-PheGAA, tRNA:F:GAA:AE002708-a" CR31588 16-Dec-15 2015_12 FBgn0069099 mus326 mutagen-sensitive 326 http://flybase.net/reports/FBgn0069099.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0028616 l(2)W1 lethal (2) W1 http://flybase.net/reports/FBgn0028616.html gene l(2R)W1 16-Dec-15 2015_12 "lethal,recessive" FBgn0267473 CR45823 http://flybase.net/reports/FBgn0267473.html non_protein_coding_gene CR45823 16-Dec-15 2015_12 FBgn0267777 CR46108 http://flybase.net/reports/FBgn0267777.html non_protein_coding_gene CR46108 16-Dec-15 2015_12 FBgn0033984 Lap1 Lap1 http://flybase.net/reports/FBgn0033984.html protein_coding_gene 0017016=Ras GTPase binding "0007163=establishment or maintenance of cell polarity, 0015031=protein transport" 0005912=adherens junction "dLAP1, CG10255, CT28815, dlap1" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat, IPR001478=PDZ domain" CG10255 16-Dec-15 2015_12 "ENSXETG00000012373(LRRC7),ENSXETG00000000448(erbb2ip),ENSXETG00000001618(lrrc1)" "ENSMUSG00000028176(Lrrc7),ENSMUSG00000021709(Erbb2ip)" "ENSG00000033122(LRRC7),ENSG00000112851(ERBB2IP)" viable FBgn0267624 CR45962 http://flybase.net/reports/FBgn0267624.html non_protein_coding_gene CR45962 16-Dec-15 2015_12 FBgn0065331 l(2)SH1882 lethal (2) SH1882 http://flybase.net/reports/FBgn0065331.html gene l(2)SH2 1882 16-Dec-15 2015_12 "lethal,recessive" FBgn0020930 Dgkëµ Diacyl glycerol kinase ëµ http://flybase.net/reports/FBgn0020930.html protein_coding_gene "0019992=diacylglycerol binding, 0004143=diacylglycerol kinase activity" "0007205=protein kinase C-activating G-protein coupled receptor signaling pathway, 0016310=phosphorylation, 0035556=intracellular signal transduction" "Diacyl glycerol kinase epsilon, CG8657, DGKe, dgkepsilon, DGKepsilon, unnamed, diacylglycerol kinase epsilon, Dgkepsilon" "IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR001206=Diacylglycerol kinase, catalytic domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000756=Diacylglycerol kinase, accessory domain" CG8657 16-Dec-15 2015_12 ENSDARG00000059735(dgke) WBGene00000959(dgk-2) ENSXETG00000001324(DGKE) ENSMUSG00000000276(Dgke) ENSG00000153933(DGKE) "viable,fertile,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0085792 CR41509 http://flybase.net/reports/FBgn0085792.html FBan0041509 pseudogene_attribute CR41509 16-Dec-15 2015_12 FBgn0011958 tRNA:R2:42Ad transfer RNA:arg2:42Ad http://flybase.net/reports/FBgn0011958.html "FBgn0003757, FBgn0011947, FBgn0050304, FBgn0060091" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033429=CGU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:arg2:42Ad, chr2R.trna1-ArgACG, tRNA:arg1, tRNA[Arg], tRNA:R1, transfer RNA:arg1, tRNA[arg], AE002769.trna10-ArgACG, CR30304, 35DArg, tRNA[Arg][[2]], tRNA:R:ACG:AE002769-b" CR30304 16-Dec-15 2015_12 FBgn0262097 CR42850 http://flybase.net/reports/FBgn0262097.html non_protein_coding_gene CG42850 CR42850 16-Dec-15 2015_12 FBgn0259832 CG34229 http://flybase.net/reports/FBgn0259832.html "FBgn0085258, FBgn0033655" protein_coding_gene "Sdh6, CG13191" "IPR008011=Complex 1 LYR protein, IPR026868=LYR motif-containing protein 2" CG34229 16-Dec-15 2015_12 ENSDARG00000033138(si:dkey-181i3.3) ENSXETG00000012750() ENSMUSG00000045854(Lyrm2) "ENSG00000083099(LYRM2),ENSG00000205748" FBgn0262291 mir-956 mir-956 stem loop http://flybase.net/reports/FBgn0262291.html miRNA_gene "CR42998, dme-miR-956, miR-956, dme-mir-956, dme-miR-956-5p" CR42998 16-Dec-15 2015_12 viable FBgn0025455 CycT Cyclin T http://flybase.net/reports/FBgn0025455.html FBgn0023101 protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0019901=protein kinase binding, 0008353=RNA polymerase II carboxy-terminal domain kinase activity" "0009408=response to heat, 0006351=transcription, DNA-templated, 0008360=regulation of cell shape, 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0007015=actin filament organization, 0000278=mitotic cell cycle, 0006355=regulation of transcription, DNA-templated" "0005634=nucleus, 0032783=ELL-EAF complex, 0008024=positive transcription elongation factor complex b, 0005703=polytene chromosome puff, 0005700=polytene chromosome" "anon-74EFc, dT, cyclin T2, Dmcyclin T, cyclin T, unnamed, p124, ORE-14, CyclinT, P-TEFb, CG6292, cyclin T1, dCyclin T" "IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal, IPR015429=Cyclin C/H/T/L, IPR015430=Cyclin T" CG6292 16-Dec-15 2015_12 "ENSDARG00000036685(ccnt2a),ENSDARG00000036510(ccnt2b),ENSDARG00000017525(si:dkey-18f23.10)" "ENSXETG00000000488(CCNT2),ENSXETG00000009784(CCNT1)" "ENSMUSG00000026349(Ccnt2),ENSMUSG00000011960(Ccnt1)" "ENSG00000082258(CCNT2),ENSG00000129315(CCNT1)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC23304 IEK 0.026374515 4.105745829 1.594790678 -3.290926669 2.870076554 4.172031086 FBgn0053988 Mid1 Mid1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0053988.html "FBgn0035051, FBgn0035052, FBgn0035053, FBtr0072438, FBpp0072343, FBtr0072439, FBpp0072344, FBtr0072440, FBpp0072345" protein_coding_gene "0045475=locomotor rhythm, 0035176=social behavior" "CG33988, CG18510, CG13596, cg13596, CG13595" IPR029604=Transmembrane protein FAM155 CG33988 16-Dec-15 2015_12 "locomotor rhythm defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "chaeta,supernumerary" DRSC04231 K -0.747885446 0.148291502 -0.347758993 0.29937545 -1.509966451 -0.782567918 FBgn0021947 l(2)k10502 lethal (2) k10502 http://flybase.net/reports/FBgn0021947.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0084065 2.2.2 2.2.2 http://flybase.net/reports/FBgn0084065.html gene 16-Dec-15 2015_12 visible eye FBgn0013739 usdy unsteady http://flybase.net/reports/FBgn0013739.html gene "0007399=nervous system development, 0007625=grooming behavior" 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0024927 Su(var)2-b801 Su(var)2-b801 http://flybase.net/reports/FBgn0024927.html gene Su-var(2)b801 16-Dec-15 2015_12 FBgn0063383 snoRNA:U29:54Ec snoRNA:U29:54Ec http://flybase.net/reports/FBgn0063383.html snoRNA_gene "U29snoRNA, chr2R:13215315..13215434, CR32894" CR32894 16-Dec-15 2015_12 FBgn0051225 Ir94f Ionotropic receptor 94f http://flybase.net/reports/FBgn0051225.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG31225, IR94f, DmelIR94f, ionotropic receptor 94f" CG31225 16-Dec-15 2015_12 FBgn0060487 l(3)S110408 lethal (3) S110408 http://flybase.net/reports/FBgn0060487.html gene 1104/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0014118 anon-96Fc anon-96Fc http://flybase.net/reports/FBgn0014118.html gene C transcript 16-Dec-15 2015_12 " adult stage , larval stage " " adult head

, eye-antennal disc

" FBgn0260007 CG42493 http://flybase.net/reports/FBgn0260007.html protein_coding_gene CG42493 16-Dec-15 2015_12 FBgn0053399 5SrRNA:CR33399 5SrRNA:CR33399 http://flybase.net/reports/FBgn0053399.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33399 CR33399 16-Dec-15 2015_12 FBgn0262428 mir-87 mir-87 stem loop http://flybase.net/reports/FBgn0262428.html "FBgn0046814, FBgn0262276" miRNA_gene "mir-87, CR32981, miR-87, CR42983" CR42983 16-Dec-15 2015_12 " embryonic stage , prepupal stage--adult stage , larval stage | first instar , larval stage | second instar " "viable,visible" wing FBgn0010371 meso60A mesoderm specific 60A http://flybase.net/reports/FBgn0010371.html gene 16-Dec-15 2015_12 FBgn0016808 l(1)L1 lethal (1) L1 http://flybase.net/reports/FBgn0016808.html gene L1 16-Dec-15 2015_12 "lethal,recessive" FBgn0003451 snl sonless http://flybase.net/reports/FBgn0003451.html gene 16-Dec-15 2015_12 "lethal,male,maternal effect,recessive,partially lethal - majority die" FBgn0019735 l(1)9e3-21 lethal (1) 9e3-21 http://flybase.net/reports/FBgn0019735.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266154 CR44860 http://flybase.net/reports/FBgn0266154.html non_protein_coding_gene CR44860 16-Dec-15 2015_12 FBgn0030880 CG6788 http://flybase.net/reports/FBgn0030880.html protein_coding_gene 0007155=cell adhesion "AAF48780, Fibrinogen-related protein, FBpp0074269" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR020837=Fibrinogen, conserved site, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG6788 16-Dec-15 2015_12 WBGene00017013(D1009.3) "ENSMUSG00000033860(Fgg),ENSMUSG00000031594(Fgl1),ENSMUSG00000033831(Fgb),ENSMUSG00000039899(Fgl2),ENSMUSG00000028989(Angptl7),ENSMUSG00000059807(Fga)" "ENSG00000171557(FGG),ENSG00000104760(FGL1),ENSG00000171819(ANGPTL7),ENSG00000127951(FGL2)" viable FBgn0000431 den denervated http://flybase.net/reports/FBgn0000431.html gene 16-Dec-15 2015_12 nervous system FBgn0261615 CG42704 http://flybase.net/reports/FBgn0261615.html protein_coding_gene CG42704 16-Dec-15 2015_12 FBgn0024646 l(2)k09810 lethal (2) k09810 http://flybase.net/reports/FBgn0024646.html gene 16-Dec-15 2015_12 FBgn0065944 l(2)SH0108 lethal (2) SH0108 http://flybase.net/reports/FBgn0065944.html gene l(2)SH2 0108 16-Dec-15 2015_12 "lethal,recessive" FBgn0029815 CG11462 http://flybase.net/reports/FBgn0029815.html FBgn0062501 protein_coding_gene BcDNA:GH09844 16-Dec-15 2015_12 viable DRSC25663 K -1.617307862 -0.236999708 FBgn0024790 Doc\RTase RTase http://flybase.net/reports/FBgn0024790.html transposable_element_gene "RT, ORF2" "IPR005135=Endonuclease/exonuclease/phosphatase, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0038740 CG4562 http://flybase.net/reports/FBgn0038740.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" 0055085=transmembrane transport 0043190=ATP-binding cassette (ABC) transporter complex "Dme_CG4562, CT14766" "IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG4562 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) viable FBgn0051219 CG31219 http://flybase.net/reports/FBgn0051219.html FBgn0038724 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis CG16731 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG31219 16-Dec-15 2015_12 viable FBgn0016726 RpL29 Ribosomal protein L29 http://flybase.net/reports/FBgn0016726.html "FBgn0025285, FBgn0025305, FBgn0061374" protein_coding_gene "0003682=chromatin binding, 0003735=structural constituent of ribosome" 0006412=translation "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "BcDNA:RH58777, RpL43, 60S ribosomal protein L43, 60S ribosomal component, L29, anon-EST:Posey73, CG10071, DL43, anon-EST:Posey204" IPR002673=Ribosomal protein L29e CG10071 16-Dec-15 2015_12 YFR032C-A(RPL29) WBGene00004443(rpl-29) ENSXETG00000010811(RPL29) ENSG00000162244(RPL29) FBgn0044490 DTD46.8 DTD46.8 http://flybase.net/reports/FBgn0044490.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034486 CG13869 http://flybase.net/reports/FBgn0034486.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG13869 16-Dec-15 2015_12 FBgn0032359 Osi21 Osiris 21 http://flybase.net/reports/FBgn0032359.html protein_coding_gene 0005887=integral component of plasma membrane "CG14925, Osiris" IPR012464=Protein of unknown function DUF1676 CG14925 16-Dec-15 2015_12 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000661 fl(1)302 female lethal 302 http://flybase.net/reports/FBgn0000661.html gene 16-Dec-15 2015_12 "lethal,female,viable,male" FBgn0264872 CR44063 http://flybase.net/reports/FBgn0264872.html non_protein_coding_gene CR44063 16-Dec-15 2015_12 FBgn0034013 unc-5 unc-5 http://flybase.net/reports/FBgn0034013.html FBgn0034014 protein_coding_gene "0005042=netrin receptor activity, 0005043=netrin receptor activity involved in chemorepulsion" "0007165=signal transduction, 0007411=axon guidance, 0008347=glial cell migration, 0007432=salivary gland boundary specification, 0008045=motor neuron axon guidance" "UNC5, Uncoordinated5, CG8166, AAF7419, Unc5, UNC-5, Unc5d, UNC5 protein, Unc-5, CG8168, uncoordinated 5, dUnc5, CT20824, unc5, UNC5D, Dunc5, unc-5-like" "IPR000488=Death domain, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR003599=Immunoglobulin subtype, IPR011029=Death-like domain, IPR000906=ZU5 domain, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2" CG8166 16-Dec-15 2015_12 WBGene00006745(unc-5) "ENSXETG00000019901(UNC5B),ENSXETG00000019221(UNC5C),ENSXETG00000013401(UNC5D)" "ENSMUSG00000020099(Unc5b),ENSMUSG00000059921(Unc5c),ENSMUSG00000063626(Unc5d),ENSMUSG00000025876(Unc5a)" "ENSG00000107731(UNC5B),ENSG00000182168(UNC5C),ENSG00000156687(UNC5D),ENSG00000113763(UNC5A)" "neuroanatomy defective,locomotor rhythm defective,lethal,viable" "intersegmental nerve,anterior commissure,posterior commissure,ventral nerve cord,embryonic/larval neuron,interface glial cell | embryonic stage,abdominal segmental nerve,presumptive embryonic salivary gland,serotonin neuron & ventral nerve cordeg-Mz360,cell body & serotonin neuroneg-Mz360,interface glial cell,ventral nerve cord commissure,longitudinal connective,photoreceptor cell R7,peripheral glial cell,embryonic peripheral glial cell 6,embryonic peripheral glial cell 8,embryonic peripheral glial cell 5" FBgn0001174 halo halo http://flybase.net/reports/FBgn0001174.html FBgn0031346 protein_coding_gene "0007018=microtubule-based movement, 0032879=regulation of localization, 0006869=lipid transport, 0042325=regulation of phosphorylation, 0031887=lipid particle transport along microtubule" CG7428 IPR007970=Protein of unknown function DUF733 CG7428 16-Dec-15 2015_12 " embryonic stage | gastrula , embryonic stage | cycle 13-14 " " organism | restricted

, organism

" viable FBgn0259629 B1112 http://flybase.net/reports/FBgn0259629.html gene 16-Dec-15 2015_12 visible "1st posterior cell,wing,anterior crossvein" FBgn0040006 CG12595 http://flybase.net/reports/FBgn0040006.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267518 2SrRNA-ë¬:CR45858 2S ribosomal RNA pseudogene:CR45858 http://flybase.net/reports/FBgn0267518.html pseudogene_attribute CR45858 CR45858 16-Dec-15 2015_12 FBgn0014913 anon-4Fg anon-4Fg http://flybase.net/reports/FBgn0014913.html gene 16-Dec-15 2015_12 FBgn0262814 CG43185 http://flybase.net/reports/FBgn0262814.html protein_coding_gene CG43185 16-Dec-15 2015_12 FBgn0005580 l(1)J1674 lethal (1) J1674 http://flybase.net/reports/FBgn0005580.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0053700 CG33700 http://flybase.net/reports/FBgn0053700.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33700 16-Dec-15 2015_12 FBgn0035233 Pex10 Peroxin 10 http://flybase.net/reports/FBgn0035233.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0007112=male meiosis cytokinesis, 0045046=protein import into peroxisome membrane, 0016567=protein ubiquitination, 0007031=peroxisome organization, 0016558=protein import into peroxisome matrix, 0007285=primary spermatocyte growth, 0007286=spermatid development, 0048137=spermatocyte division, 0042760=very long-chain fatty acid catabolic process" "0005778=peroxisomal membrane, 0005777=peroxisome, 0005779=integral component of peroxisomal membrane" "CG7864, DmelPex10, peroxin 10, PEX10, pex10" "IPR025654=Peroxisome biogenesis factor 10, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR006845=Pex, N-terminal" CG7864 16-Dec-15 2015_12 ENSDARG00000041511(pex10) YDR265W(PEX10) ENSXETG00000012096(PEX10) ENSMUSG00000029047(Pex10) ENSG00000157911(PEX10) "viable,female semi-fertile,male sterile,developmental rate defective,cytokinesis defective,meiotic cell cycle defective" "spermatid,testis" FBgn0263544 mir-4949 mir-4949 stem loop http://flybase.net/reports/FBgn0263544.html miRNA_gene "CR43529, dme-mir-4949" CR43529 16-Dec-15 2015_12 FBgn0036504 yellow-k yellow-k http://flybase.net/reports/FBgn0036504.html protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "yell-k, CG7463" IPR017996=Major royal jelly protein/Protein yellow CG7463 16-Dec-15 2015_12 FBgn0267413 CG45766 http://flybase.net/reports/FBgn0267413.html protein_coding_gene CG45766 16-Dec-15 2015_12 FBgn0084848 l(3)S057101 l(3)S057101 http://flybase.net/reports/FBgn0084848.html gene 16-Dec-15 2015_12 FBgn0004143 nullo nullo http://flybase.net/reports/FBgn0004143.html FBgn0062443 protein_coding_gene 0003779=actin binding "0000915=actomyosin contractile ring assembly, 0007349=cellularization, 0036089=cleavage furrow formation, 0008104=protein localization, 0016331=morphogenesis of embryonic epithelium, 0008360=regulation of cell shape, 0007043=cell-cell junction assembly, 0030036=actin cytoskeleton organization" "0005912=adherens junction, 0005884=actin filament, 0005911=cell-cell junction" "Nullo, CG14426, BcDNA:RE47733" CG14426 16-Dec-15 2015_12 " embryonic stage | cycle 14 , embryonic stage | cycle 11-14 , embryonic stage | embryonic cycle 11..14 " " organism

,

{ 0 Sry-&agr;- } " embryonic stage | embryonic cycle 13-16 "lethal,partially,recessive,heat sensitive,wild-type,partially lethal - majority die,viable,cold sensitive" "cleavage stage embryo,spot adherens junctionmat.ë±Tub67C.THsimVP16,ventral furrow,zonula adherensmat.ë±Tub67C.THsimVP16,embryonic/first instar larval cuticle,epithelial cell | embryonic stage" FBgn0020869 anon-R100 anon-R100 http://flybase.net/reports/FBgn0020869.html gene 2-R100 16-Dec-15 2015_12 "fertile,chemical sensitive,dominant" FBgn0052480 tRNA:CR32480 transfer RNA:CR32480 http://flybase.net/reports/FBgn0052480.html FBgn0060193 tRNA_gene 0033435=AUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna1-IleTAT, tRNA:I:TAT:AE002584-a, CR32480, AE002584.trna1-IleTAT" CR32480 16-Dec-15 2015_12 FBgn0264412 FCE-E http://flybase.net/reports/FBgn0264412.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0084003 CG41436 http://flybase.net/reports/FBgn0084003.html FBan0041436 protein_coding_gene 16-Dec-15 2015_12 FBgn0060443 l(3)S123206b lethal (3) S123206b http://flybase.net/reports/FBgn0060443.html gene 1232/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0035205 CG2469 http://flybase.net/reports/FBgn0035205.html protein_coding_gene "0016570=histone modification, 0006355=regulation of transcription, DNA-templated" 0016593=Cdc73/Paf1 complex cg2469 "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR031101=RNA polymerase-associated protein Ctr9, IPR019734=Tetratricopeptide repeat" CG2469 16-Dec-15 2015_12 ENSDARG00000009170(ctr9) YOL145C(CTR9) WBGene00007184(B0464.2) ENSXETG00000013673(CTR9) ENSMUSG00000005609(Ctr9) ENSG00000198730(CTR9) DRSC27308 IK 1.009217821 1.785318917 1.068706652 -0.184405856 2.249199394 1.818445458 FBgn0066102 Krn::spi Krn::spi http://flybase.net/reports/FBgn0066102.html engineered_fusion_gene 16-Dec-15 2015_12 wing FBgn0060896 l(3)S044339 lethal (3) S044339 http://flybase.net/reports/FBgn0060896.html gene 0443/39 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0263620 CR43629 http://flybase.net/reports/FBgn0263620.html non_protein_coding_gene CR43629 16-Dec-15 2015_12 FBgn0026199 myo myoglianin http://flybase.net/reports/FBgn0026199.html FBgn0064928 protein_coding_gene 0008083=growth factor activity 0016319=mushroom body development "Myo, MYO, myg, CG1838, BcDNA:LD02307, myoglianin, myo, Myoglianin" "IPR017948=Transforming growth factor beta, conserved site, IPR029034=Cystine-knot cytokine, IPR015615=Transforming growth factor-beta-related, IPR001839=Transforming growth factor-beta, C-terminal" CG1838 16-Dec-15 2015_12 "ENSDARG00000044924(gdf11),ENSDARG00000069133(mstnb),ENSDARG00000042947(mstna)" WBGene00000903(daf-7) "ENSXETG00000021861(GDF11),ENSXETG00000009890(MSTN)" "ENSMUSG00000025352(Gdf11),ENSMUSG00000026100(Mstn)" "ENSG00000135414(GDF11),ENSG00000138379(MSTN)" " larval stage , embryonic stage | stage >=15 , embryonic stage | early , embryonic stage | stage 6 , embryonic stage | stage 11 , embryonic stage -- adult stage , embryonic stage | stage 14 " " glial cell

, embryonic/larval visceral muscle

, pole plasm

, pole cell

, glioblast

, visceral muscle &&of embryonic heart

, embryonic/larval somatic muscle

" "developmental rate defective,recessive,neuroanatomy defective,lethal,majority die during larval stage,viable,cell growth defective,circadian rhythm defective,heat sensitive" "gamma Kenyon cell,adult mushroom body,wing,embryonic/larval neuromuscular junction | larval stage,transverse nerve" FBgn0034106 CG9068 http://flybase.net/reports/FBgn0034106.html protein_coding_gene 0003774=motor activity 0005875=microtubule associated complex "IPR013594=Dynein heavy chain, domain-1" CG9068 16-Dec-15 2015_12 ENSDARG00000013098 viable FBgn0038912 CG6656 http://flybase.net/reports/FBgn0038912.html protein_coding_gene 0003993=acid phosphatase activity 0016311=dephosphorylation "0005634=nucleus, 0070062=extracellular exosome" "IPR000560=Histidine phosphatase superfamily, clade-2, IPR029033=Histidine phosphatase superfamily" CG6656 16-Dec-15 2015_12 viable FBgn0041619 SM2-1 SM2-1 http://flybase.net/reports/FBgn0041619.html gene 16-Dec-15 2015_12 FBgn0266964 CR45415 http://flybase.net/reports/FBgn0266964.html non_protein_coding_gene CR45415 16-Dec-15 2015_12 FBgn0034267 CG4984 http://flybase.net/reports/FBgn0034267.html protein_coding_gene 0016021=integral component of membrane IPR004031=PMP-22/EMP/MP20/Claudin superfamily CG4984 16-Dec-15 2015_12 "ENSDARG00000003326(LOC797409),ENSDARG00000039240(LOC100331116),ENSDARG00000063006(si:dkey-21p19.1),ENSDARG00000070624(LOC100003278)" "ENSMUSG00000022715(Tmem114),ENSMUSG00000070330(Gm12581)" "ENSG00000105605(CACNG7),ENSG00000075429(CACNG5),ENSG00000075461(CACNG4),ENSG00000166862(CACNG2),ENSG00000006116(CACNG3),ENSG00000142408(CACNG8)" "viable,visible" "chaeta,supernumerary" DRSC06908 K -0.371250086 0.270635387 0.01322685 0.124959741 1.528127654 -0.385284918 FBgn0037050 ICA69 ICA69 http://flybase.net/reports/FBgn0037050.html protein_coding_gene 0019904=protein domain specific binding 0046928=regulation of neurotransmitter secretion 0000139=Golgi membrane "ICA69, dCG10566-PA, Dm ric-19, CG10566" "IPR024116=Resistance to inhibitors of cholinesterase protein 19, IPR010504=Arfaptin homology (AH) domain, IPR024114=Islet cell autoantigen 1/Ica1-like, IPR027267=Arfaptin homology (AH) domain/BAR domain" CG10566 16-Dec-15 2015_12 "ENSDARG00000057688(LOC100330486),ENSDARG00000042608" WBGene00004368(ric-19) ENSXETG00000007286(ica1) "ENSMUSG00000062995(Ica1),ENSMUSG00000026018(Ica1l)" "ENSG00000003147(ICA1),ENSG00000163596(ICA1L)" viable FBgn0058466 CG40466 http://flybase.net/reports/FBgn0058466.html protein_coding_gene 16-Dec-15 2015_12 FBgn0052376 CG32376 http://flybase.net/reports/FBgn0052376.html FBgn0035796 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP148, CG8528" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG32376 16-Dec-15 2015_12 "viable,fertile" FBgn0039472 CG17192 http://flybase.net/reports/FBgn0039472.html protein_coding_gene "0008970=phosphatidylcholine 1-acylhydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "Triglyceride lipase, DmelL5" "IPR002334=Vespid venom allergen phospholipase A1, IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG17192 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) viable FBgn0035273 CG12020 http://flybase.net/reports/FBgn0035273.html protein_coding_gene 0051082=unfolded protein binding "0009408=response to heat, 0006457=protein folding" "IPR008971=HSP40/DnaJ peptide-binding, IPR002939=Chaperone DnaJ, C-terminal, IPR001623=DnaJ domain" CG12020 16-Dec-15 2015_12 viable FBgn0039810 CG15549 http://flybase.net/reports/FBgn0039810.html FBgn0063753 protein_coding_gene 0022008=neurogenesis BcDNA:AT07554 CG15549 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0002256 l(3)68Fa lethal (3) 68Fa http://flybase.net/reports/FBgn0002256.html gene "rose-gespleten region interval 18, l(3)rsg18, l(3)F11, l(3)V4-5, rsg18" 16-Dec-15 2015_12 lethal FBgn0060346 l(3)S143301b lethal (3) S143301b http://flybase.net/reports/FBgn0060346.html gene 1433/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0265498 CR44367 http://flybase.net/reports/FBgn0265498.html non_protein_coding_gene CR44367 16-Dec-15 2015_12 FBgn0011628 l(2)T57a18 lethal (2) T57a18 http://flybase.net/reports/FBgn0011628.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0262463 mir-100 mir-100 stem loop http://flybase.net/reports/FBgn0262463.html "FBgn0064160, FBgn0053313, FBgn0262337" miRNA_gene 0071390=cellular response to ecdysone "CR43044, CR33313, mir-100, dme-mir-100, Dme-miR-100, miR-100" CR43044 16-Dec-15 2015_12 prepupal stage--adult stage FBgn0028253 l(3)84Ch lethal (3) 84Ch http://flybase.net/reports/FBgn0028253.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0058294 CG40294 http://flybase.net/reports/FBgn0058294.html FBan0040294 protein_coding_gene 16-Dec-15 2015_12 FBgn0061088 l(3)S011524 lethal (3) S011524 http://flybase.net/reports/FBgn0061088.html FBgn0060723 gene "0682/12, l(3)S068212, 0115/24" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0264431 CR43849 http://flybase.net/reports/FBgn0264431.html non_protein_coding_gene CR43849 16-Dec-15 2015_12 FBgn0051785 CG31785 http://flybase.net/reports/FBgn0051785.html protein_coding_gene CG31785 16-Dec-15 2015_12 viable FBgn0024364 CG11417 http://flybase.net/reports/FBgn0024364.html protein_coding_gene 0022008=neurogenesis 0005634=nucleus EG:8D8.4 IPR012580=NUC153 CG11417 16-Dec-15 2015_12 ENSDARG00000008740(zgc:66241) YDR365C(ESF1) WBGene00010231(F58B3.4) ENSXETG00000008079() ENSMUSG00000045624(Esf1) ENSG00000089048(ESF1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0013611 l(3)EX-G13 lethal (3) EX-G13 http://flybase.net/reports/FBgn0013611.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001200 His4 Histone H4 http://flybase.net/reports/FBgn0001200.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0016321=female meiosis chromosome segregation, 0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005694=chromosome, 0035059=RCAF complex, 0000786=nucleosome, 0000228=nuclear chromosome" "his4, DmeH4, H4_DROME, histone H4, H4, Bicoid interacting protein 2, Histone, core histone, Bin2, HisC, dH4, histone 4, H4Ac16, 4, his, histone" "IPR001951=Histone H4, IPR019809=Histone H4, conserved site, IPR009072=Histone-fold" 16-Dec-15 2015_12 " egg stage | fertilized egg , adult stage " " male pronucleus

, spermatozoon

, spermatid | late

, spermatid | early

, female pronucleus

" "meiotic cell cycle defective,dominant" FBgn0003725 tms tumorous http://flybase.net/reports/FBgn0003725.html gene 16-Dec-15 2015_12 "viable,fertile,visible" FBgn0067764 l(1)16-3-98 lethal (1) 16-3-98 http://flybase.net/reports/FBgn0067764.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060645 l(3)S084013b lethal (3) S084013b http://flybase.net/reports/FBgn0060645.html gene 0840/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0083281 E(smoDN)2243 Enhancer of smoDN 2243 http://flybase.net/reports/FBgn0083281.html gene 16-Dec-15 2015_12 FBgn0033826 CG4734 http://flybase.net/reports/FBgn0033826.html protein_coding_gene IPR000859=CUB domain CG4734 16-Dec-15 2015_12 FBgn0267591 CR45929 http://flybase.net/reports/FBgn0267591.html non_protein_coding_gene CR45929 16-Dec-15 2015_12 FBgn0014954 dl::zen2 dl::zen2 http://flybase.net/reports/FBgn0014954.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0021757 bub bubblewing http://flybase.net/reports/FBgn0021757.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces "bubblwing, 2L-A" 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0051445 CG31445 http://flybase.net/reports/FBgn0051445.html FBgn0039657 protein_coding_gene "0008237=metallopeptidase activity, 0004177=aminopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis 0016021=integral component of membrane CG11955 "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain" CG31445 16-Dec-15 2015_12 FBgn0260475 CG30059 http://flybase.net/reports/FBgn0260475.html "FBgn0050059, FBgn0044652" protein_coding_gene 0008449=N-acetylglucosamine-6-sulfatase activity "0030203=glycosaminoglycan metabolic process, 0006044=N-acetylglucosamine metabolic process" 0005764=lysosome anon-WO0140519.22 "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR012251=N-acetylglucosamine-6-sulfatase, IPR024607=Sulfatase, conserved site, IPR017850=Alkaline-phosphatase-like, core domain, IPR000917=Sulfatase" CG30059 16-Dec-15 2015_12 viable FBgn0023222 E(Egfr)C22 Enhancer of Egfr C22 http://flybase.net/reports/FBgn0023222.html gene 16-Dec-15 2015_12 FBgn0038921 CG6332 http://flybase.net/reports/FBgn0038921.html FBgn0044639 protein_coding_gene "anon-WO0140519.231, cg6332" IPR006623=Testicular haploid expressed repeat CG6332 16-Dec-15 2015_12 viable FBgn0034092 CG7798 http://flybase.net/reports/FBgn0034092.html protein_coding_gene 0003796=lysozyme activity 0019730=antimicrobial humoral response "IPR019799=Glycoside hydrolase, family 22, conserved site, IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain" CG7798 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) FBgn0085548 CG40972 http://flybase.net/reports/FBgn0085548.html FBan0040972 protein_coding_gene 16-Dec-15 2015_12 FBgn0020180 Dfd::ro Dfd::ro http://flybase.net/reports/FBgn0020180.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0033087 Hsepi Heparan sulfate C5-epimerase http://flybase.net/reports/FBgn0033087.html protein_coding_gene "0016857=racemase and epimerase activity, acting on carbohydrates and derivatives" 0006024=glycosaminoglycan biosynthetic process 0016021=integral component of membrane "Heparan sulfate glucuronyl C5-epimerase, CG3194, C5-epimerase" IPR010598=D-glucuronyl C5-epimerase CG3194 16-Dec-15 2015_12 "ENSDARG00000005095(glcea),ENSDARG00000068981(glceb)" WBGene00002003(hse-5) ENSXETG00000007825(GLCE) ENSMUSG00000032252(Glce) ENSG00000138604(GLCE) "viable,partially lethal - majority die,fertile,increased mortality during development,short lived" "posterior crossvein,wing vein,wing sensillum,wing vein L5" FBgn0003315 satDNA satellite DNA http://flybase.net/reports/FBgn0003315.html satellite_DNA "satellite I, SATI, SatIII, microsatellite, stDNA, 1.686, sc1, MSs, unnamed, 1.688, SSR, SATIII, SAR-DM, microsatellites, satellite repeat, satellite III" 16-Dec-15 2015_12 FBgn0065399 l(2)SH1605 lethal (2) SH1605 http://flybase.net/reports/FBgn0065399.html gene l(2)SH2 1605 16-Dec-15 2015_12 "lethal,recessive" FBgn0265830 CR44619 http://flybase.net/reports/FBgn0265830.html non_protein_coding_gene lincRNA.984 CR44619 16-Dec-15 2015_12 FBgn0083301 E(smoDN)1736 Enhancer of smoDN 1736 http://flybase.net/reports/FBgn0083301.html gene 16-Dec-15 2015_12 FBgn0020908 Scp1 Sarcoplasmic calcium-binding protein 1 http://flybase.net/reports/FBgn0020908.html "FBgn0039982, FBgn0063247, FBan0015848" protein_coding_gene 0005509=calcium ion binding 0016529=sarcoplasmic reticulum "CG15848, BcDNA:GH15296, Drosophila Ca[2+]-binding protein A.1, SCP, calcium biding protein, SCP1, Sarcoplasmic calcium binding protein 1, Dcabp-A.1" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG15848 16-Dec-15 2015_12 adult stage mesothoracic extracoxal depressor muscle 66 | restricted

DRSC20806 K 0.450544992 -0.222693531 0.704376164 0.44088234 0.128092375 1.677009178 FBgn0004584 Rrp1 Recombination repair protein 1 http://flybase.net/reports/FBgn0004584.html protein_coding_gene "0008311=double-stranded DNA 3'-5' exodeoxyribonuclease activity, 0003906=DNA-(apurinic or apyrimidinic site) lyase activity, 0003677=DNA binding, 0008408=3'-5' exonuclease activity" "0006281=DNA repair, 0006974=cellular response to DNA damage stimulus" "0005634=nucleus, 0005622=intracellular" "CG3178, RRP1, strand transferase, Recombination Repair Protein 1, rrp, Rrp-1, RRP1_DROME, 3178" "IPR004808=AP endonuclease 1, IPR005135=Endonuclease/exonuclease/phosphatase, IPR020848=AP endonuclease 1, conserved site, IPR020847=AP endonuclease 1, binding site" CG3178 16-Dec-15 2015_12 WBGene00001372(exo-3) " embryonic stage | early , adult stage | female " viable DRSC26575 IK -1.895582074 -0.475131465 -0.366809517 -0.173639136 0.097521337 2.397591801 FBgn0013503 l(1)PB7 lethal (1) PB7 http://flybase.net/reports/FBgn0013503.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0270927 ë_Glu ë_ glucuronidase http://flybase.net/reports/FBgn0270927.html "FBgn0001111, FBgn0039874" protein_coding_gene 0004566=beta-glucuronidase activity 0005975=carbohydrate metabolic process 0031224=intrinsic component of membrane "Glu, beta-Glucuronidase, CG2135, Glc, gus, beta-GUS" "IPR013812=Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain, IPR006104=Glycosyl hydrolases family 2, sugar binding domain, IPR006102=Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR013781=Glycoside hydrolase, catalytic domain, IPR008979=Galactose-binding domain-like, IPR006101=Glycoside hydrolase, family 2, IPR006103=Glycoside hydrolase family 2, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR023230=Glycoside hydrolase, family 2, conserved site" CG2135 16-Dec-15 2015_12 ENSDARG00000063126(gusb) WBGene00013693(Y105E8B.9) ENSXETG00000010042() ENSMUSG00000025534(Gusb) ENSG00000169919(GUSB) viable FBgn0033970 CG10205 http://flybase.net/reports/FBgn0033970.html protein_coding_gene CT28709 CG10205 16-Dec-15 2015_12 viable FBgn0060331 l(3)S145701a lethal (3) S145701a http://flybase.net/reports/FBgn0060331.html gene 1457/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0014263 oho55DE overgrown hematopoietic organs 55DE http://flybase.net/reports/FBgn0014263.html gene 0048542=lymph gland development "l(2)k13104, l(2)k03007, l(2)30/7, oho55D,E" 16-Dec-15 2015_12 "lethal,hyperplasia,recessive" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0261361 CG42638 http://flybase.net/reports/FBgn0261361.html protein_coding_gene noncoding_13567 "IPR013122=Polycystin cation channel, PKD1/PKD2" CG42638 16-Dec-15 2015_12 FBgn0037063 CG9391 http://flybase.net/reports/FBgn0037063.html protein_coding_gene 0008934=inositol monophosphate 1-phosphatase activity "0016311=dephosphorylation, 0046855=inositol phosphate dephosphorylation, 0046854=phosphatidylinositol phosphorylation" 0005737=cytoplasm "142335_at, IMP" "IPR020550=Inositol monophosphatase, conserved site, IPR020583=Inositol monophosphatase, metal-binding site, IPR020552=Inositol monophosphatase, Lithium-sensitive, IPR000760=Inositol monophosphatase" CG9391 16-Dec-15 2015_12 "ENSDARG00000003517(impa1),ENSDARG00000059411(zgc:110201)" "YDR287W(INM2),YHR046C(INM1)" WBGene00008765(ttx-7) "ENSXETG00000010421(impa1),ENSXETG00000019694(IMPA2)" "ENSMUSG00000027531(Impa1),ENSMUSG00000024525(Impa2)" "ENSG00000133731(IMPA1),ENSG00000141401(IMPA2)" "viable,fertile" FBgn0039348 Npl4 Npl4 ortholog http://flybase.net/reports/FBgn0039348.html protein_coding_gene "0017056=structural constituent of nuclear pore, 0008270=zinc ion binding" "0098586=cellular response to virus, 0006511=ubiquitin-dependent protein catabolic process, 0022008=neurogenesis" "0005829=cytosol, 0005643=nuclear pore, 0005654=nucleoplasm" "NPL4, dNpl4, dNp14, dNPLOC4, npl4, CG4673, Npl4" "IPR007717=Nuclear pore localisation protein NPL4, IPR024682=Nuclear pore localisation protein Npl4, ubiquitin-like domain, IPR029071=Ubiquitin-related domain, IPR016563=Polyubiquitin-tagged protein recognition complex, Npl4 component, IPR007716=NPL4, zinc-binding putative, IPR001876=Zinc finger, RanBP2-type" CG4673 16-Dec-15 2015_12 "ENSDARG00000071393(nploc4),ENSDARG00000020511" YBR170C(NPL4) "WBGene00019120(npl-4.1),WBGene00019121(npl-4.2)" ENSXETG00000015038(NPLOC4) ENSMUSG00000039703(Nploc4) ENSG00000182446(NPLOC4) "lethal,neuroanatomy defective,stress response defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032047 CG13088 http://flybase.net/reports/FBgn0032047.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO15 CG13088 16-Dec-15 2015_12 WBGene00007168(B0393.3) viable FBgn0033821 CG10799 http://flybase.net/reports/FBgn0033821.html protein_coding_gene CT30256 CG10799 16-Dec-15 2015_12 viable FBgn0044063 GTD74-1 GTD74-1 http://flybase.net/reports/FBgn0044063.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041239 Gr58a Gustatory receptor 58a http://flybase.net/reports/FBgn0041239.html FBgn0050396 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "58A.1, GR58A.1, 58A1, Gr58A1, Gustatory receptor 58A.1, CG30396" IPR013604=7TM chemoreceptor CG30396 16-Dec-15 2015_12 viable FBgn0267938 CR46218 http://flybase.net/reports/FBgn0267938.html non_protein_coding_gene lincRNA.764 CR46218 16-Dec-15 2015_12 FBgn0062668 EP3085 EP3085 http://flybase.net/reports/FBgn0062668.html gene EP(3)3085 16-Dec-15 2015_12 FBgn0043890 l(3)C101 lethal (3) C101 http://flybase.net/reports/FBgn0043890.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 "lethal,recessive" FBgn0040219 fs(2)BG07 fs(2)BG07 http://flybase.net/reports/FBgn0040219.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0022405 Est-10 Esterase 10 http://flybase.net/reports/FBgn0022405.html gene EST-10 16-Dec-15 2015_12 FBgn0035726 CG9953 http://flybase.net/reports/FBgn0035726.html protein_coding_gene "0004185=serine-type carboxypeptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis "IPR029058=Alpha/Beta hydrolase fold, IPR008758=Peptidase S28" CG9953 16-Dec-15 2015_12 ENSDARG00000029353 WBGene00019682(K12H4.7) ENSXETG00000008182() ENSMUSG00000006179(Prss16) ENSG00000112812(PRSS16) viable FBgn0004140 fs(2)43Ei female sterile (2) 43Ei http://flybase.net/reports/FBgn0004140.html FBgn0014247 gene 16-Dec-15 2015_12 female sterile abdominal tergite marginal bristle FBgn0020577 anon-59Ch anon-59Ch http://flybase.net/reports/FBgn0020577.html gene 16-Dec-15 2015_12 FBgn0011282 Obp84a Odorant-binding protein 84a http://flybase.net/reports/FBgn0011282.html protein_coding_gene "0005549=odorant binding, 0008145=phenylalkylamine binding, 0005550=pheromone binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG1176, pbprp-4, Pheromone-binding protein-related protein 4, 84a, pbprp4, Obp84a, PBPRP-4, PBP4, PBPRP4, Pbprp4, DmelObp84a" IPR006170=Pheromone/general odorant binding protein CG1176 16-Dec-15 2015_12 adult stage sensillum trichodeum of antennal segment 3 | subset

FBgn0000307 chif chiffon http://flybase.net/reports/FBgn0000307.html FBgn0028842 protein_coding_gene "0030295=protein kinase activator activity, 0003677=DNA binding, 0008270=zinc ion binding" "0045860=positive regulation of protein kinase activity, 0007306=eggshell chorion assembly, 0006275=regulation of DNA replication, 0007307=eggshell chorion gene amplification, 0007304=chorion-containing eggshell formation, 0045740=positive regulation of DNA replication, 0046716=muscle cell cellular homeostasis, 0072499=photoreceptor cell axon guidance" 0031431=Dbf4-dependent protein kinase complex "fs(2)chiffon, CG5813, Chiffon, BG:DS09218.2, CG5817, chf, BG:DS09218.1, Dbf4, DS09218.1, Chif" "IPR006572=Zinc finger, DBF-type, IPR017956=AT hook, DNA-binding motif" CG5813 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10-11 , embryonic stage | early , adult stage && oogenesis stage | stage S13-14 " " nurse cell

, follicle cell

" "female sterile,wild-type,recessive,visible,viable" "chorion,eye,scutellar bristle,trichogen cell" FBgn0030597 Eo Ecdysone oxidase http://flybase.net/reports/FBgn0030597.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0047875=ecdysone oxidase activity" "0055114=oxidation-reduction process, 0008205=ecdysone metabolic process" "DmEO, EObeta1, CG9504, ecdysone oxidase" "IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132=Glucose-methanol-choline oxidoreductase" CG9504 16-Dec-15 2015_12 viable FBgn0034104 CG15705 http://flybase.net/reports/FBgn0034104.html protein_coding_gene 0000164=protein phosphatase type 1 complex CG15705 16-Dec-15 2015_12 viable FBgn0053985 CG33985 http://flybase.net/reports/FBgn0053985.html "FBgn0036506, FBgn0036507" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "unnamed, CG17014, FBgn0036507, CG7973" IPR002557=Chitin binding domain CG33985 16-Dec-15 2015_12 FBgn0021862 l(2)k14206 lethal (2) k14206 http://flybase.net/reports/FBgn0021862.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0084702 G87 G87 http://flybase.net/reports/FBgn0084702.html gene 16-Dec-15 2015_12 FBgn0040543 CG14699 http://flybase.net/reports/FBgn0040543.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030456 CG4332 http://flybase.net/reports/FBgn0030456.html protein_coding_gene 0006915=apoptotic process "0012505=endomembrane system, 0016021=integral component of membrane" "IPR008429=Cleft lip and palate transmembrane 1, IPR030434=Cleft lip and palate transmembrane protein 1-like protein" CG4332 16-Dec-15 2015_12 ENSDARG00000021048(clptm1l) WBGene00011761(T13H5.8) ENSXETG00000015645(CLPTM1L) ENSMUSG00000021610(Clptm1l) ENSG00000049656(CLPTM1L) viable FBgn0051108 CG31108 http://flybase.net/reports/FBgn0051108.html "FBgn0039278, FBgn0064125" protein_coding_gene 0004835=tubulin-tyrosine ligase activity 0006464=cellular protein modification process CG10057 IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase CG31108 16-Dec-15 2015_12 ENSDARG00000036793 ENSXETG00000013220(TTLL5) ENSMUSG00000012609(Ttll5) FBgn0035875 Cpr66Cb Cuticular protein 66Cb http://flybase.net/reports/FBgn0035875.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG7076, DmelCpr66Cb" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG7076 16-Dec-15 2015_12 viable FBgn0016964 vm1 visible mutation-1 http://flybase.net/reports/FBgn0016964.html gene 16-Dec-15 2015_12 visible wing FBgn0262786 CG43167 http://flybase.net/reports/FBgn0262786.html protein_coding_gene CG43167 16-Dec-15 2015_12 FBgn0265917 CR44706 http://flybase.net/reports/FBgn0265917.html pseudogene_attribute "lincRNA.143, CG44706" CR44706 16-Dec-15 2015_12 FBgn0030780 CG13008 http://flybase.net/reports/FBgn0030780.html FBgn0030779 protein_coding_gene CG13009 CG13008 16-Dec-15 2015_12 viable DRSC19527 K -0.546601767 0.239391157 0.750980368 -0.394071535 -1.160765221 -1.680958718 FBgn0000966 fs(2)eo1 female sterile (2) eo1 http://flybase.net/reports/FBgn0000966.html gene 0048477=oogenesis "fs(2)eo-D, fs(2)eoPV30" 16-Dec-15 2015_12 "female sterile,male sterile" FBgn0019906 anon-14Bd anon-14Bd http://flybase.net/reports/FBgn0019906.html gene unnamed 16-Dec-15 2015_12 FBgn0032961 CG1416 http://flybase.net/reports/FBgn0032961.html protein_coding_gene "0051087=chaperone binding, 0001671=ATPase activator activity" 0006950=response to stress "IPR015310=Activator of Hsp90 ATPase, N-terminal, IPR023393=START-like domain, IPR013538=Activator of Hsp90 ATPase homologue 1-like" CG1416 16-Dec-15 2015_12 "ENSDARG00000011127(ahsa1l),ENSDARG00000028664(ahsa1)" YDR214W(AHA1) WBGene00007235(C01G10.8) ENSXETG00000011083(Q66IH8_XENTR) "ENSMUSG00000021037(Ahsa1),ENSMUSG00000020288(Ahsa2)" "ENSG00000100591(AHSA1),ENSG00000173209(AHSA2)" viable FBgn0082328 HM857 HM857 http://flybase.net/reports/FBgn0082328.html gene 16-Dec-15 2015_12 FBgn0060538 l(3)S100309b lethal (3) S100309b http://flybase.net/reports/FBgn0060538.html gene 1003/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0030352 sicily severe impairment of CI with lengthened youth http://flybase.net/reports/FBgn0030352.html protein_coding_gene 0016740=transferase activity "0009058=biosynthetic process, 0050821=protein stabilization" "0005739=mitochondrion, 0005737=cytoplasm" "XE07, CG15738" "IPR002060=Squalene/phytoene synthase, IPR008949=Isoprenoid synthase domain" CG15738 16-Dec-15 2015_12 ENSDARG00000053652(gb:bc097249) WBGene00007145(B0334.5) ENSMUSG00000050323(2310030N02Rik) ENSG00000156170(C8orf38) "neurophysiology defective,progressive,somatic clone,lethal - all die during pupal stage,viable" "mitochondrion | progressive | somatic clone,rhabdomere | progressive | somatic clone,retinal pigment cell,somatic clone,eye photoreceptor cell,progressive" FBgn0016628 E(gl)2D Enhancer of glass 2D http://flybase.net/reports/FBgn0016628.html gene 16-Dec-15 2015_12 "lethal,recessive" rhabdomere FBgn0067741 l(1)G0304 lethal (1) G0304 http://flybase.net/reports/FBgn0067741.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036093 CG14154 http://flybase.net/reports/FBgn0036093.html protein_coding_gene IPR027831=Domain of unknown function DUF4485 CG14154 16-Dec-15 2015_12 viable FBgn0023175 Prosë±7 Proteasome ë±7 subunit http://flybase.net/reports/FBgn0023175.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005839=proteasome core complex, 0005875=microtubule associated complex, 0000502=proteasome complex, 0019773=proteasome core complex, alpha-subunit complex" "20S proteasome, CG1519, 20s proteasome, Alpha-7, PROSalpha7, Proteasome alpha7 subunit, 20S proteasome subunit alpha-7, alpha7, 20S proteasome subunit alpha 7, Proteasome subunit alpha type-3, alpha-subunit of 20S proteasome, Alpha7, CPalpha7, alpha-7, alpha7_dm, 1519, Prosalpha7, PSA3_DROME" "IPR001353=Proteasome, subunit alpha/beta, IPR023332=Proteasome A-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000426=Proteasome alpha-subunit, N-terminal domain" CG1519 16-Dec-15 2015_12 ENSDARG00000044452 YOR362C(PRE10) WBGene00003928(pas-7) ENSXETG00000011978(psma3) ENSMUSG00000060073(Psma3) ENSG00000100567(PSMA3) "lethal,female sterile,meiotic cell cycle defective,male limited" "testis,spermatocyte" DRSC07516 IEK -2.369788221 -1.831585002 -1.59495144 -1.149419065 2.36275368 1.404835938 FBgn0047038 ND-13B NADH dehydrogenase (ubiquinone) 13 kDa B subunit http://flybase.net/reports/FBgn0047038.html FBgn0036100 protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH ubiquinone oxidoreductase 13 kDa B, BcDNA:RH11203, NADH:ubiquinone oxidoreductase 13 kDa B subunit, NADH-ubiquinone oxidoreductase 13 kDa-B subunit, NUFM, CG6463" IPR006806=ETC complex I subunit CG6463 16-Dec-15 2015_12 ENSDARG00000039346(zgc:114172) WBGene00007880(C33A12.1) ENSXETG00000027688(ndufa5) ENSMUSG00000023089(Ndufa5) "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0064117 SLIRP1 SRA stem-loop interacting RNA binding protein 1 http://flybase.net/reports/FBgn0064117.html "FBgn0031172, FBgn0053071, FBgn0053714, FBtr0077227, FBpp0076922, FBtr0077228, FBtr0077229, FBpp0076924, FBtr0077230" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding" "CG33071, CG33714, CG33071-ORFA, Dromel_CG33713_FBtr0091704_uORF, cg1704, CG1704, CG33071ORFA, DmSLIRP1" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG33714 16-Dec-15 2015_12 ENSDARG00000041299(zgc:110796) WBGene00008224(C50B8.1) ENSXETG00000021349() ENSMUSG00000021040(1810035L17Rik) ENSG00000119705(SLIRP) "feeding behavior defective,smell perception defective" FBgn0028112 l(3)S066317 lethal (3) S066317 http://flybase.net/reports/FBgn0028112.html gene 0663/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0001764 l(1)M24 lethal (1) M24 http://flybase.net/reports/FBgn0001764.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026392 Or33a Odorant receptor 33a http://flybase.net/reports/FBgn0026392.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity, 0004888=transmembrane signaling receptor activity" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "Olfactory receptor 33B.1, Or33B.1, 33a, Or73, DOR73, DOR33B.1, dor73, AN3, 33B.1, CG16960" "IPR004117=Olfactory receptor, Drosophila" CG16960 16-Dec-15 2015_12 sensory neuron &&of antennal segment 3

"viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0044116 E(rst)C137 E(rst)C137 http://flybase.net/reports/FBgn0044116.html gene 0001745=compound eye morphogenesis C137 16-Dec-15 2015_12 viable FBgn0030996 CG14194 http://flybase.net/reports/FBgn0030996.html protein_coding_gene IPR019396=Transmembrane Fragile-X-F-associated protein CG14194 16-Dec-15 2015_12 ENSDARG00000044327(zgc:63572) WBGene00013789(Y116A8C.9) ENSXETG00000007744() "ENSMUSG00000037015(Tmem185b),ENSMUSG00000073139(BC023829)" ENSG00000155984(TMEM185A) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0040910 CG12685 http://flybase.net/reports/FBgn0040910.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030161 CG15249 http://flybase.net/reports/FBgn0030161.html protein_coding_gene CG15249 16-Dec-15 2015_12 FBgn0000489 Pka-C3 "Protein kinase, cAMP-dependent, catalytic subunit 3" http://flybase.net/reports/FBgn0000489.html FBgn0004631 protein_coding_gene "0004691=cAMP-dependent protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005515=protein binding, 0005524=ATP binding" "0006468=protein phosphorylation, 0007476=imaginal disc-derived wing morphogenesis" 0005952=cAMP-dependent protein kinase complex "pka-C3, PKA-C3, PKA-C-3, Pk72A, Pk?5, Swiss Cheese, Protein-kinase-like-72A, PKA, CG6117, Dpck, cAMP-dependent protein kinase, PKA C3, DC2, cAMP-activated protein kinase A, 5-23, cAMP-dependent protein kinase 3" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal" CG6117 16-Dec-15 2015_12 ENSDARG00000060716(LOC561941) "YPL203W(TPK2),YKL166C(TPK3),YJL164C(TPK1)" ENSXETG00000005000() ENSMUSG00000035725(Prkx) "ENSG00000183943(PRKX),ENSG00000099725" " embryonic stage | stage 5 , pupal stage && adult stage , embryonic stage | cellular blastoderm , embryonic stage -- adult stage , embryonic stage | syncytial blastoderm " " organism | pair rule

, head mesoderm

,

ventral " "viable,fertile,visible,dominant" wing DRSC11254 IE 1.554634272 0.423352256 1.313304075 -4.195554011 0.417488872 0.606234897 FBgn0040528 CG15864 http://flybase.net/reports/FBgn0040528.html FBgn0037558 protein_coding_gene "0005506=iron ion binding, 0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum CG7553 "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG15864 16-Dec-15 2015_12 FBgn0011070 l(1)Q23 lethal (1) Q23 http://flybase.net/reports/FBgn0011070.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0265071 CR44182 http://flybase.net/reports/FBgn0265071.html non_protein_coding_gene CR44182 16-Dec-15 2015_12 FBgn0042627 FASN2 Fatty acid synthase 2 http://flybase.net/reports/FBgn0042627.html FBgn0031502 protein_coding_gene "0004312=fatty acid synthase activity, 0016491=oxidoreductase activity, 0004314=[acyl-carrier-protein] S-malonyltransferase activity, 0004313=[acyl-carrier-protein] S-acetyltransferase activity, 0004315=3-oxoacyl-[acyl-carrier-protein] synthase activity, 0016788=hydrolase activity, acting on ester bonds, 0008270=zinc ion binding" "0055114=oxidation-reduction process, 0006723=cuticle hydrocarbon biosynthetic process, 1902321=methyl-branched fatty acid biosynthetic process, 0071329=cellular response to sucrose stimulus" 0005811=lipid particle "v(2)k05816, FAS, Fatty acid synthase, methyl-branched specific, methyl-branched specific FAS, fatty acid synthase 2, FAS[CG3524], mbCHC-specific FAS, FAS-mb, DM_7295849, mFAS, FASN[CG3524], CG3524" "IPR014031=Beta-ketoacyl synthase, C-terminal, IPR014030=Beta-ketoacyl synthase, N-terminal, IPR016036=Malonyl-CoA ACP transacylase, ACP-binding, IPR001227=Acyl transferase domain, IPR001031=Thioesterase, IPR013968=Polyketide synthase, ketoreductase domain, IPR013149=Alcohol dehydrogenase, C-terminal, IPR009081=Acyl carrier protein-like, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase, IPR016039=Thiolase-like, IPR011032=GroES-like, IPR020807=Polyketide synthase, dehydratase domain, IPR018201=Beta-ketoacyl synthase, active site, IPR020843=Polyketide synthase, enoylreductase domain, IPR016040=NAD(P)-binding domain, IPR014043=Acyl transferase, IPR029058=Alpha/Beta hydrolase fold" CG3524 16-Dec-15 2015_12 "ENSDARG00000068882,ENSDARG00000068878(si:dkey-61p9.11),ENSDARG00000071470" WBGene00009342(fasn-1) ENSXETG00000019666(FASN) ENSMUSG00000025153(Fasn) ENSG00000169710(FASN) "visible,lethal - all die before end of pupal stage,viable" "wing,leg" FBgn0026233 hab habanero http://flybase.net/reports/FBgn0026233.html gene 0009950=dorsal/ventral axis specification jabanero 16-Dec-15 2015_12 FBgn0024491 Bin1 Bicoid interacting protein 1 http://flybase.net/reports/FBgn0024491.html "FBgn0038406, FBgn0047185" protein_coding_gene "0008134=transcription factor binding, 0003714=transcription corepressor activity, 0005515=protein binding" "0000398=mRNA splicing, via spliceosome, 0006342=chromatin silencing, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated" "0071011=precatalytic spliceosome, 0005634=nucleus, 0016580=Sin3 complex, 0071013=catalytic step 2 spliceosome" "bin1, Bin 1, dSAP18, SAP18, SIN3-associated polypeptide 18, BcDNA:RE02417, CG6046, dSap18, bin1/dSAP18, 150001_at, dsap18, Sin3A-associated polypeptide p18, sap18" "IPR010516=Sin3 associated polypeptide p18, IPR017250=Histone deacetylase complex, SAP18 subunit" CG6046 16-Dec-15 2015_12 "ENSDARG00000069915,ENSDARG00000057854(sap18)" WBGene00007625(C16C10.4) ENSXETG00000009598(sap18) "ENSMUSG00000061104(Gm10094),ENSMUSG00000021963(Sap18)" ENSG00000150459(SAP18) "visible,homeotic,enhancer of variegation,lethal,recessive,heat sensitive,viable,maternal effect" "abdominal sternite bristle,ectopic,adult abdominal segment 6,adult abdominal segment 5,embryonic/first instar larval cuticle,anterior,germline clone,cephalopharyngeal skeleton" FBgn0031853 TTLL3B Tubulin tyrosine ligase-like 3B http://flybase.net/reports/FBgn0031853.html protein_coding_gene "0007291=sperm individualization, 0018094=protein polyglycylation" "dmTTLL3B, CG11201" IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase CG11201 16-Dec-15 2015_12 "viable,male fertile,female fertile,partially lethal - majority die,male sterile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" spermatid axoneme DRSC02133 IE 0.306881315 2.168655715 2.306026001 -0.025771814 0.213225408 0.714066771 FBgn0084463 Brkd Breakdance http://flybase.net/reports/FBgn0084463.html gene 16-Dec-15 2015_12 "behavior defective,dominant,heat sensitive,neurophysiology defective,recessive" "indirect flight muscle,heat sensitive" FBgn0037516 CG11286 http://flybase.net/reports/FBgn0037516.html protein_coding_gene 0046331=lateral inhibition CG11286 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary,trichogen cell,tormogen cell,wing" FBgn0002040 l(2)37Dd lethal (2) 37Dd http://flybase.net/reports/FBgn0002040.html FBgn0002042 gene "l(2)OE36, l(2)37Df, l(2)OD8" 16-Dec-15 2015_12 partially lethal - majority die FBgn0083155 S(smoDN)1657 Suppressor of smoDN 1657 http://flybase.net/reports/FBgn0083155.html gene 16-Dec-15 2015_12 FBgn0032652 CG6870 http://flybase.net/reports/FBgn0032652.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding" 0043231=intracellular membrane-bounded organelle cytochrome B5 "IPR018506=Cytochrome b5, heme-binding site, IPR001199=Cytochrome b5-like heme/steroid binding domain" CG6870 16-Dec-15 2015_12 FBgn0036497 Ran-like Ran-like http://flybase.net/reports/FBgn0036497.html "FBgn0044729, FBgn0047302" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0006886=intracellular protein transport, 0007264=small GTPase mediated signal transduction, 0006913=nucleocytoplasmic transport" 0005634=nucleus "Ran-like, ran-like, CG7815, anon-WO0140519.150, BcDNA:GH25818" "IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR002041=Ran GTPase" CG7815 16-Dec-15 2015_12 viable FBgn0259260 EP-1052 http://flybase.net/reports/FBgn0259260.html gene 16-Dec-15 2015_12 visible wing FBgn0266379 CR45021 http://flybase.net/reports/FBgn0266379.html non_protein_coding_gene CR45021 16-Dec-15 2015_12 FBgn0039107 CG10300 http://flybase.net/reports/FBgn0039107.html protein_coding_gene "0008431=vitamin E binding, 0005215=transporter activity" 0006810=transport 0005622=intracellular "IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR011074=CRAL/TRIO, N-terminal domain" CG10300 16-Dec-15 2015_12 viable FBgn0259234 Camta Calmodulin-binding transcription activator http://flybase.net/reports/FBgn0259234.html "FBgn0033417, FBgn0033415, FBgn0033416" protein_coding_gene "0042803=protein homodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005516=calmodulin binding" "0016059=deactivation of rhodopsin mediated signaling, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0009416=response to light stimulus, 0045893=positive regulation of transcription, DNA-templated" 0005634=nucleus "calmodulin-binding transcription activator, CG42332, CG8809, Calmodulin-binding transcription factor, CG13953, Camta, dCAMTA, camta, CG13952, DmCAMTA" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR005559=CG-1 DNA-binding domain, IPR000048=IQ motif, EF-hand binding site, IPR002909=IPT domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014756=Immunoglobulin E-set" CG42332 16-Dec-15 2015_12 WBGene00020251(T05C1.4) ENSXETG00000017389(CAMTA2) "ENSMUSG00000014592(Camta1),ENSMUSG00000040712(Camta2)" "ENSG00000171735(CAMTA1),ENSG00000108509(CAMTA2)" FBgn0052631 CG32631 http://flybase.net/reports/FBgn0052631.html FBgn0030496 protein_coding_gene CG1733 CG32631 16-Dec-15 2015_12 viable FBgn0013772 Cyp6a8 Cytochrome P450-6a8 http://flybase.net/reports/FBgn0013772.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0018685=alkane 1-monooxygenase activity, 0005506=iron ion binding" "0017143=insecticide metabolic process, 0048252=lauric acid metabolic process, 0055114=oxidation-reduction process, 0031000=response to caffeine" "0016020=membrane, 0012505=endomembrane system, 0043231=intracellular membrane-bounded organelle" "cytochrome P450, 6a8, P-450, P450, cytochrome P450 related AF5, Cyt-P450-rAF5, CYP6A8, CG10248" "IPR002402=Cytochrome P450, E-class, group II, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG10248 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" adult stage viable FBgn0061126 l(3)S003405b lethal (3) S003405b http://flybase.net/reports/FBgn0061126.html gene 0034/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0027167 l(2)IH2 lethal (2) IH2 http://flybase.net/reports/FBgn0027167.html gene unnamed 16-Dec-15 2015_12 lethal FBgn0065087 snmRNA:649 small non-messenger RNA 649 http://flybase.net/reports/FBgn0065087.html FBgn0053685 non_protein_coding_gene "CR33685, Dm-649" CR33685 16-Dec-15 2015_12 FBgn0004439 prd2 paired-like 2 http://flybase.net/reports/FBgn0004439.html gene PRD gene 2 16-Dec-15 2015_12 FBgn0053494 CG33494 http://flybase.net/reports/FBgn0053494.html FBgn0064911 protein_coding_gene BcDNA:LP10657 CG33494 16-Dec-15 2015_12 viable DRSC13715 I 1.720135242 -1.469636193 0.046769554 -1.213704151 0.108345919 -0.538793309 FBgn0267104 CG45544 http://flybase.net/reports/FBgn0267104.html protein_coding_gene lincRNA.886 CG45544 16-Dec-15 2015_12 FBgn0033471 CG12134 http://flybase.net/reports/FBgn0033471.html protein_coding_gene "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG12134 16-Dec-15 2015_12 "ENSDARG00000069115,ENSDARG00000069120" YNL035C() ENSXETG00000003583(TEgg008m17.1) ENSMUSG00000045690(Wdr89) ENSG00000140006(WDR89) "viable,fertile" FBgn0283433 CG46276 http://flybase.net/reports/FBgn0283433.html protein_coding_gene CG46276 16-Dec-15 2015_12 FBgn0033740 dgt5 dim ë_-tubulin 5 http://flybase.net/reports/FBgn0033740.html protein_coding_gene "0007052=mitotic spindle organization, 0007088=regulation of mitotic nuclear division" "0005875=microtubule associated complex, 0070652=HAUS complex, 0005819=spindle" "mitotic spindle density 2, msd2, Dgt5, CG8828" CG8828 16-Dec-15 2015_12 viable FBgn0036343 CG14115 http://flybase.net/reports/FBgn0036343.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG14115 16-Dec-15 2015_12 viable FBgn0030300 Sk1 Sphingosine kinase 1 http://flybase.net/reports/FBgn0030300.html protein_coding_gene "0004143=diacylglycerol kinase activity, 0017050=D-erythro-sphingosine kinase activity" "0016310=phosphorylation, 0006665=sphingolipid metabolic process" "0005886=plasma membrane, 0005829=cytosol" "Sphk1, SK1, CG1747, Sphingosine kinase I" "IPR001206=Diacylglycerol kinase, catalytic domain, IPR016064=NAD kinase/diacylglycerol kinase-like domain" CG1747 16-Dec-15 2015_12 ENSDARG00000069893 "YOR171C(LCB4),YLR260W(LCB5)" WBGene00007918(sphk-1) "ENSXETG00000003163(SPHK2),ENSXETG00000019540(sphk1)" ENSMUSG00000057342(Sphk2) ENSG00000063176(SPHK2) "viable,fertile" rhabdomereGMR.PF FBgn0065172 l(3)SH020 lethal (3) SH020 http://flybase.net/reports/FBgn0065172.html gene l(2)SH3 020 16-Dec-15 2015_12 "lethal,recessive" FBgn0266229 CR44924 http://flybase.net/reports/FBgn0266229.html non_protein_coding_gene lincRNA.681 CR44924 16-Dec-15 2015_12 FBgn0067776 fkl fraenkel http://flybase.net/reports/FBgn0067776.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 lethal FBgn0038163 CG10841 http://flybase.net/reports/FBgn0038163.html FBgn0044588 protein_coding_gene 0005509=calcium ion binding anon-WO0140519.42 "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG10841 16-Dec-15 2015_12 "viable,fertile" FBgn0014381 rip ripcord http://flybase.net/reports/FBgn0014381.html FBgn0015503 gene "XBB70 Group VIII, VIII, l(3)65Da, unnamed" 16-Dec-15 2015_12 "lethal,recessive" FBgn0005758 l(1)TK402 lethal (1) TK402 http://flybase.net/reports/FBgn0005758.html gene l402 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" eye FBgn0052452 CG32452 http://flybase.net/reports/FBgn0052452.html FBgn0046216 protein_coding_gene BcDNA:SD04526 CG32452 16-Dec-15 2015_12 DRSC11581 I -1.700754986 0.827866467 0.840033113 -0.38521593 -0.111060082 0.937626534 FBgn0013387 anon-100CDb anon-100CDb http://flybase.net/reports/FBgn0013387.html gene 16-Dec-15 2015_12 FBgn0037700 CG8149 http://flybase.net/reports/FBgn0037700.html protein_coding_gene "0048102=autophagic cell death, 0035167=larval lymph gland hemopoiesis, 0048190=wing disc dorsal/ventral pattern formation, 0035071=salivary gland cell autophagic cell death" IPR003034=SAP domain CG8149 16-Dec-15 2015_12 ENSDARG00000059357(zgc:109957) WBGene00021813(Y53G8AR.6) ENSXETG00000024657(TTpA003a20.1) ENSG00000205323(SARNP) "viable,visible" trichogen cell FBgn0025572 RNA-guanine-7-methyltransferase RNA (guanine-7-)methyltransferase http://flybase.net/reports/FBgn0025572.html gene 0008176=tRNA (guanine-N7-)-methyltransferase activity 16-Dec-15 2015_12 FBgn0004751 l(3)89Bd lethal (3) 89Bd http://flybase.net/reports/FBgn0004751.html gene 16-Dec-15 2015_12 lethal FBgn0052228 CG32228 http://flybase.net/reports/FBgn0052228.html protein_coding_gene CG32228 16-Dec-15 2015_12 viable FBgn0084013 CG41449 http://flybase.net/reports/FBgn0084013.html FBan0041449 protein_coding_gene 16-Dec-15 2015_12 FBgn0031913 CG5958 http://flybase.net/reports/FBgn0031913.html protein_coding_gene "0005215=transporter activity, 0016918=retinal binding" 0006810=transport 0005811=lipid particle "IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG5958 16-Dec-15 2015_12 ENSDARG00000070644(ttpal) ENSXETG00000017770(rlbp1) ENSMUSG00000017679(Ttpal) ENSG00000124120(TTPAL) viable FBgn0036775 CG5147 http://flybase.net/reports/FBgn0036775.html protein_coding_gene "0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity" 0006383=transcription from RNA polymerase III promoter 0005666=DNA-directed RNA polymerase III complex IPR007811=DNA-directed RNA polymerase III subunit RPC4 CG5147 16-Dec-15 2015_12 "ENSDARG00000017820,ENSDARG00000042054" YDL150W(RPC53) ENSXETG00000010534(polr3d) ENSMUSG00000000776(Polr3d) ENSG00000168495(POLR3D) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260050 2L4332 http://flybase.net/reports/FBgn0260050.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0036565 CG5235 http://flybase.net/reports/FBgn0036565.html protein_coding_gene "0004500=dopamine beta-monooxygenase activity, 0005507=copper ion binding" 0055114=oxidation-reduction process "IPR014784=Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR000945=Dopamine beta-hydroxylase-related, IPR008977=PHM/PNGase F domain, IPR005018=DOMON domain, IPR024548=Copper type II ascorbate-dependent monooxygenase, C-terminal, IPR020611=Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site, IPR000323=Copper type II, ascorbate-dependent monooxygenase, N-terminal" CG5235 16-Dec-15 2015_12 ENSDARG00000031136(moxd1) ENSMUSG00000020000(Moxd1) ENSG00000079931(MOXD1) "viable,fertile" FBgn0086233 hN13 http://flybase.net/reports/FBgn0086233.html gene 16-Dec-15 2015_12 FBgn0262211 mir-2498 mir-2498 stem loop http://flybase.net/reports/FBgn0262211.html miRNA_gene "dme-mir-2498, CR42918, chou22" CR42918 16-Dec-15 2015_12 viable FBgn0032814 CG10366 http://flybase.net/reports/FBgn0032814.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG10366 16-Dec-15 2015_12 viable FBgn0005447 l(1)v219 lethal (1) v219 http://flybase.net/reports/FBgn0005447.html gene l(1)219 16-Dec-15 2015_12 FBgn0032371 CG4983 http://flybase.net/reports/FBgn0032371.html FBgn0044747 protein_coding_gene anon-WO0140519.134 CG4983 16-Dec-15 2015_12 viable FBgn0040240 bc2 buckled on 2 http://flybase.net/reports/FBgn0040240.html gene "bc, buckled" 16-Dec-15 2015_12 visible wing FBgn0035293 CG5687 http://flybase.net/reports/FBgn0035293.html FBgn0027683 protein_coding_gene 0008507=sodium:iodide symporter activity 0055085=transmembrane transport 0016020=membrane "anon-EST:Posey42, dSLC5A2" "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG5687 16-Dec-15 2015_12 YHL016C(DUR3) WBGene00014092(ZK822.5) viable FBgn0267716 CR46049 http://flybase.net/reports/FBgn0267716.html non_protein_coding_gene Mgn1733 CR46049 16-Dec-15 2015_12 FBgn0022298 l(1)M123.2 lethal (1) M123.2 http://flybase.net/reports/FBgn0022298.html gene M123.2 16-Dec-15 2015_12 "lethal,recessive" FBgn0014278 l(2)k17039 lethal (2) k17039 http://flybase.net/reports/FBgn0014278.html gene l(2)170/39 16-Dec-15 2015_12 "lethal,recessive" FBgn0262878 CG43233 http://flybase.net/reports/FBgn0262878.html protein_coding_gene CG43233 16-Dec-15 2015_12 FBgn0262001 CG42819 http://flybase.net/reports/FBgn0262001.html "FBgn0032037, FBan0013394" protein_coding_gene CG13394 CG42819 16-Dec-15 2015_12 DRSC02265 EK 0.561094474 0.668251357 4.116655123 0.374203322 -0.641144644 -1.887395999 FBgn0039040 CG13833 http://flybase.net/reports/FBgn0039040.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG13833 16-Dec-15 2015_12 viable FBgn0050416 CG30416 http://flybase.net/reports/FBgn0050416.html "FBgn0034843, FBgn0065018" protein_coding_gene "BcDNA:AT11052, CG9803" CG30416 16-Dec-15 2015_12 viable FBgn0013994 Nc98F Neural conserved at 98F http://flybase.net/reports/FBgn0013994.html gene NC98F 16-Dec-15 2015_12 FBgn0250893 zaa77f10 http://flybase.net/reports/FBgn0250893.html gene zaa77f10y1 16-Dec-15 2015_12 FBgn0263996 CG43739 http://flybase.net/reports/FBgn0263996.html protein_coding_gene Dm_2L:110584 CG43739 16-Dec-15 2015_12 FBgn0267534 CR45874 http://flybase.net/reports/FBgn0267534.html non_protein_coding_gene Mgn3857 CR45874 16-Dec-15 2015_12 FBgn0262062 SG13 http://flybase.net/reports/FBgn0262062.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025162 l(2)49Fp lethal (2) 49Fp http://flybase.net/reports/FBgn0025162.html gene vr17 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation,dominant" FBgn0260026 CG42494 http://flybase.net/reports/FBgn0260026.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG42494 16-Dec-15 2015_12 FBgn0040586 CG17624 http://flybase.net/reports/FBgn0040586.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264529 l(3)ff5 http://flybase.net/reports/FBgn0264529.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0016722 Reg-8 Rhythmically expressed gene 8 http://flybase.net/reports/FBgn0016722.html gene "Dreg-8, Drosophila Rhythmically expressed gene 8" 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0265444 CR44344 http://flybase.net/reports/FBgn0265444.html non_protein_coding_gene CR44344 16-Dec-15 2015_12 FBgn0040377 Vha36-3 Vacuolar H+ ATPase 36kD subunit 3 http://flybase.net/reports/FBgn0040377.html FBgn0029623 protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0046961=proton-transporting ATPase activity, rotational mechanism" "0015992=proton transport, 0015991=ATP hydrolysis coupled proton transport" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0033176=proton-transporting V-type ATPase complex" "vha36-3, EG:BACR25B3.4, Vacuolar H[+] ATPase subunit 36-3, CG8310" "IPR002699=ATPase, V1 complex, subunit D" CG8310 16-Dec-15 2015_12 ENSDARG00000011175(atp6v1d) YEL051W(VMA8) WBGene00010130(vha-14) ENSXETG00000011222(ATP6V1D) ENSMUSG00000021114(Atp6v1d) ENSG00000100554(ATP6V1D) FBgn0001817 l(1)P2 lethal (1) P2 http://flybase.net/reports/FBgn0001817.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0043875 mod(mdg4)::Trl mod(mdg4)::Trl http://flybase.net/reports/FBgn0043875.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0034972 CG10339 http://flybase.net/reports/FBgn0034972.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold" CG10339 16-Dec-15 2015_12 viable FBgn0035968 Slc45-1 Slc45 ortholog 1 http://flybase.net/reports/FBgn0035968.html protein_coding_gene "0008515=sucrose transmembrane transporter activity, 0008506=sucrose:proton symporter activity" 0015770=sucrose transport "0031410=cytoplasmic vesicle, 0045177=apical part of cell" "scrt, Sucrose transporter, CG4484" IPR020846=Major facilitator superfamily domain CG4484 16-Dec-15 2015_12 "ENSDARG00000004302(zgc:158635),ENSDARG00000002593(slc45a2)" "ENSXETG00000006011(SLC45A1),ENSXETG00000002556(matp),ENSXETG00000023750(SLC45A4)" "ENSMUSG00000039838(Slc45a1),ENSMUSG00000022243(Slc45a2)" "ENSG00000162426(SLC45A1),ENSG00000164175(SLC45A2)" "partially lethal - majority die,viable" FBgn0033636 tou toutatis http://flybase.net/reports/FBgn0033636.html "FBgn0015875, FBgn0043382" protein_coding_gene "0003677=DNA binding, 0003682=chromatin binding, 0008134=transcription factor binding, 0008270=zinc ion binding, 0005515=protein binding" "0043044=ATP-dependent chromatin remodeling, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006338=chromatin remodeling, 0007399=nervous system development" "0031010=ISWI-type complex, 0005700=polytene chromosome" "Toutatis, EP(2)0622, VI, CG10897, anon-48Ad, EP622, TIP5, transcript group VI, Dm Tou, EP0622, gene VI" "IPR001876=Zinc finger, RanBP2-type, IPR004022=DDT domain, IPR018359=Bromodomain, conserved site, IPR001739=Methyl-CpG DNA binding, IPR028935=WHIM3 domain, IPR018500=DDT domain, subgroup, IPR001487=Bromodomain, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR018501=DDT domain superfamily, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR016177=DNA-binding domain, IPR028942=WHIM1 domain, IPR001965=Zinc finger, PHD-type" CG10897 16-Dec-15 2015_12 ENSDARG00000053572 WBGene00001470(flt-1) ENSXETG00000007584(BAZ2B) ENSMUSG00000026987(Baz2b) "ENSG00000123636(BAZ2B),ENSG00000076108(BAZ2A)" "viable,fertile,visible,poor,recessive,lethal" "wing,scutellar bristle,ectopic,dorsocentral bristle,supernumerary,wing vein L5,trichogen cell" FBgn0013937 E(sina)1 Enhancer of seven in absentia 1 http://flybase.net/reports/FBgn0013937.html gene 16-Dec-15 2015_12 "lethal,recessive" photoreceptor cell R7 FBgn0043586 EP595b EP595b http://flybase.net/reports/FBgn0043586.html gene "EP0595b, EP(3)0595b" 16-Dec-15 2015_12 FBgn0013226 E(var)113 E(var)113 http://flybase.net/reports/FBgn0013226.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0033233 Kdm4A Lysine (K)-specific demethylase 4A http://flybase.net/reports/FBgn0033233.html protein_coding_gene "0032454=histone demethylase activity (H3-K9 specific), 0051864=histone demethylase activity (H3-K36 specific)" "0010628=positive regulation of gene expression, 0016577=histone demethylation, 0070544=histone H3-K36 demethylation, 0045892=negative regulation of transcription, DNA-templated, 0033169=histone H3-K9 demethylation" 0005634=nucleus "KDM4A, dKDM4A, dkdm4a, dJMJD2(1), CG15835, Histone demethylase 4A" "IPR003349=JmjN domain, IPR003347=JmjC domain" CG15835 16-Dec-15 2015_12 "ENSDARG00000018782(LOC100003413),ENSDARG00000019103(jmjd2al),ENSDARG00000042729(kdm4b)" ENSMUSG00000053914(Kdm4d) "ENSG00000066135(KDM4A),ENSG00000107077(KDM4C),ENSG00000127663(KDM4B)" "viable,short lived,male limited,recessive,fertile,partially lethal,male" wing FBgn0003214 RD(1) Recovery disrupter of 1 http://flybase.net/reports/FBgn0003214.html gene "RD, Recovery Disrupter (1)" 16-Dec-15 2015_12 "fertile,reduced" FBgn0002860 Mst66D Male-specific RNA 66D http://flybase.net/reports/FBgn0002860.html gene mst349 16-Dec-15 2015_12 FBgn0003016 osp outspread http://flybase.net/reports/FBgn0003016.html "FBgn0004947, FBgn0010673, FBgn0027874, FBgn0065995" protein_coding_gene "arclike wing, alw, l(2)rJ571, unnamed, BG:DS07721.2, arc-like wing, anon-WO02059370.75, CG3479, BG:DS01486.7, BG:DS01486.5, v(2)rJ571" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG3479 16-Dec-15 2015_12 WBGene00008666(F10G8.8) ENSMUSG00000005417(Mprip) ENSG00000133030(MPRIP) "visible,recessive,partially lethal - majority die,lethal,viable,fertile,eye color defective" "crystal cell,wing,thorax" FBgn0041578 BC1 BC1 http://flybase.net/reports/FBgn0041578.html gene 16-Dec-15 2015_12 short lived adult FBgn0013564 l(3)ry78 lethal (3) ry78 http://flybase.net/reports/FBgn0013564.html gene l(3)78 16-Dec-15 2015_12 "lethal,recessive" FBgn0044070 E(rst)K166 E(rst)K166 http://flybase.net/reports/FBgn0044070.html gene 0001745=compound eye morphogenesis K166 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0051010 CG31010 http://flybase.net/reports/FBgn0051010.html "FBgn0045224, FBgn0063738" protein_coding_gene "NEST:bs21b05, BcDNA:AT12704" CG31010 16-Dec-15 2015_12 viable FBgn0028530 mTTF mitochondrial transcription termination factor http://flybase.net/reports/FBgn0028530.html FBgn0027850 protein_coding_gene "0003677=DNA binding, 0003690=double-stranded DNA binding" "0006355=regulation of transcription, DNA-templated, 0006393=termination of mitochondrial transcription" 0005739=mitochondrion "DmTTF, BG:DS01068.4, CG18124, DS01068.4" IPR003690=Mitochodrial transcription termination factor CG18124 16-Dec-15 2015_12 viable FBgn0046333 fs(2)38ABa fs(2)38ABa http://flybase.net/reports/FBgn0046333.html gene fs in 38A/B 16-Dec-15 2015_12 FBgn0026741 mRpL18 mitochondrial ribosomal protein L18 http://flybase.net/reports/FBgn0026741.html protein_coding_gene 0003735=structural constituent of ribosome 0032543=mitochondrial translation 0005762=mitochondrial large ribosomal subunit "MRP-L18, anon-49Ca, unnamed, HL, CG12373" CG12373 16-Dec-15 2015_12 ENSDARG00000060199(zgc:153420) WBGene00017044(D2007.4) ENSXETG00000023893(mrpl18) ENSMUSG00000057388(Mrpl18) ENSG00000112110(MRPL18) "viable,visible" trichogen cell FBgn0266397 CR45037 http://flybase.net/reports/FBgn0266397.html non_protein_coding_gene CR45037 16-Dec-15 2015_12 FBgn0259632 B0377 http://flybase.net/reports/FBgn0259632.html gene 16-Dec-15 2015_12 visible "wing,chaeta,ectopic" FBgn0054057 CG34057 http://flybase.net/reports/FBgn0054057.html FBgn0035175 protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" 0016020=membrane "dC1GalT6, CG13904" IPR003378=Fringe-like CG34057 16-Dec-15 2015_12 FBgn0036780 CG7330 http://flybase.net/reports/FBgn0036780.html FBgn0063050 protein_coding_gene BcDNA:RE22290 CG7330 16-Dec-15 2015_12 viable FBgn0037208 CG8741 http://flybase.net/reports/FBgn0037208.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038854 CG7044 http://flybase.net/reports/FBgn0038854.html protein_coding_gene "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG7044 16-Dec-15 2015_12 ENSDARG00000062585(zgc:136845) viable FBgn0037717 CG8301 http://flybase.net/reports/FBgn0037717.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG8301 16-Dec-15 2015_12 YPR186C(PZF1) "viable,fertile" FBgn0061148 l(3)S000101b lethal (3) S000101b http://flybase.net/reports/FBgn0061148.html gene 1-Jan 16-Dec-15 2015_12 "lethal,recessive" FBgn0032965 CG11629 http://flybase.net/reports/FBgn0032965.html protein_coding_gene CG11629 16-Dec-15 2015_12 FBgn0002090 l(2)56a lethal (2) 56a http://flybase.net/reports/FBgn0002090.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034965 ppk29 pickpocket 29 http://flybase.net/reports/FBgn0034965.html protein_coding_gene 0005272=sodium channel activity "0016246=RNA interference, 0006814=sodium ion transport, 0008049=male courtship behavior, 0002121=inter-male aggressive behavior" 0016021=integral component of membrane "ppk29, CG13568, nope, not passionate" "IPR001873=Na+ channel, amiloride-sensitive" CG13568 16-Dec-15 2015_12 "behavior defective,courtship behavior defective,paralytic,heat sensitive,viable,fertile,neurophysiology defective,locomotor behavior defective,male,recessive" "motor neuron,heat sensitive" FBgn0041759 eth-aS307 eth-aS307 http://flybase.net/reports/FBgn0041759.html gene eth[aS]307 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0060950 l(3)S036916c lethal (3) S036916c http://flybase.net/reports/FBgn0060950.html gene 0369/16 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal" FBgn0264337 CR43793 http://flybase.net/reports/FBgn0264337.html non_protein_coding_gene CR43793 16-Dec-15 2015_12 FBgn0029974 dpr14 defective proboscis extension response 14 http://flybase.net/reports/FBgn0029974.html protein_coding_gene 0007606=sensory perception of chemical stimulus "Dpr14, Dpr-14, CG10946, CT30653, dpr14" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain" CG10946 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) "ENSG00000105767(CADM4),ENSG00000182985(CADM1),ENSG00000175161(CADM2),ENSG00000162706(CADM3)" viable FBgn0053697 CG33697 http://flybase.net/reports/FBgn0053697.html FBgn0028845 protein_coding_gene "BG:DS08249.5, DS08249.5" 16-Dec-15 2015_12 FBgn0028097 l(3)S074103 lethal (3) S074103 http://flybase.net/reports/FBgn0028097.html gene 0741/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0024561 l(3)L5541 lethal (3) L5541 http://flybase.net/reports/FBgn0024561.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0043893 l(1)C31 lethal (1) C31 http://flybase.net/reports/FBgn0043893.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic head,salivary gland" FBgn0261041 stj straightjacket http://flybase.net/reports/FBgn0261041.html "FBgn0021940, FBgn0033870" protein_coding_gene 0005245=voltage-gated calcium channel activity "0000046=autophagic vacuole fusion, 0048488=synaptic vesicle endocytosis, 0019233=sensory perception of pain, 0007528=neuromuscular junction development, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0031629=synaptic vesicle fusion to presynaptic membrane, 0007274=neuromuscular synaptic transmission" "0048786=presynaptic active zone, 0045202=synapse, 0005891=voltage-gated calcium channel complex" "Straightjacket, alpha[[2]]delta-3, lethal (2) k10814, l(2)k10814, dalpha[[2]]delta-3, alpha[[2]]delta, CG12295" "IPR013608=VWA N-terminal, IPR004010=Cache domain, IPR002035=von Willebrand factor, type A" CG12295 16-Dec-15 2015_12 "ENSDARG00000045204,ENSDARG00000025665,ENSDARG00000026855(cacna2d4a),ENSDARG00000023886(LOC100150428)" WBGene00006772(unc-36) ENSXETG00000000081(CACNA2D2) "ENSMUSG00000021991(Cacna2d3),ENSMUSG00000041460(Cacna2d4)" "ENSG00000157445(CACNA2D3),ENSG00000151062(CACNA2D4)" FBgn0000685 flrdH flight reduced H http://flybase.net/reports/FBgn0000685.html gene 0007629=flight behavior 16-Dec-15 2015_12 "flightless,heat sensitive,jumping defective,viable,reduced,male sterile,flight defective,courtship behavior defective" FBgn0265787 CR44576 http://flybase.net/reports/FBgn0265787.html non_protein_coding_gene CR44576 16-Dec-15 2015_12 FBgn0030013 GIIIspla2 http://flybase.net/reports/FBgn0030013.html FBgn0043800 protein_coding_gene "0005509=calcium ion binding, 0004623=phospholipase A2 activity" "0016042=lipid catabolic process, 0006644=phospholipid metabolic process" "Giiispla2, BEST:HL07869, phospholipase A[[2]], CG1583, GIIIsPLA2" "IPR001211=Phospholipase A2, IPR016090=Phospholipase A2 domain, IPR013090=Phospholipase A2, active site" CG1583 16-Dec-15 2015_12 "viable,fertile" FBgn0023007 l(3)S113105 lethal (3) S113105 http://flybase.net/reports/FBgn0023007.html gene "1131/05, unnamed, 1131/5" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0021755 2R-F 2R-F http://flybase.net/reports/FBgn0021755.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 16-Dec-15 2015_12 "visible,somatic clone,viable,recessive" "wing,somatic clone" FBgn0041765 anon-d47 anon-d47 http://flybase.net/reports/FBgn0041765.html gene d47 16-Dec-15 2015_12 FBgn0021856 l(2)k14505 lethal (2) k14505 http://flybase.net/reports/FBgn0021856.html FBgn0032937 protein_coding_gene 0043461=proton-transporting ATP synthase complex assembly CG8674 "IPR023335=Orthogonal Bundle domain in ATP12, IPR011419=ATP12, ATPase F1F0-assembly protein" CG8674 16-Dec-15 2015_12 ENSDARG00000056270(atpaf2) WBGene00013804(Y116A8C.27) ENSXETG00000012153(atpaf2) ENSMUSG00000042709(Atpaf2) ENSG00000171953(ATPAF2) "lethal,recessive,viable,fertile" FBgn0010141 l(2)DTS513 lethal (2) DTS513 http://flybase.net/reports/FBgn0010141.html gene DTS513 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266010 CR44783 http://flybase.net/reports/FBgn0266010.html non_protein_coding_gene CR44783 16-Dec-15 2015_12 FBgn0027360 Tim10 Translocase of inner membrane 10 http://flybase.net/reports/FBgn0027360.html protein_coding_gene "0008565=protein transporter activity, 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity" "0015031=protein transport, 0045824=negative regulation of innate immune response, 0045039=protein import into mitochondrial inner membrane, 0006626=protein targeting to mitochondrion, 0050829=defense response to Gram-negative bacterium" "0042719=mitochondrial intermembrane space protein transporter complex, 0005744=mitochondrial inner membrane presequence translocase complex" "tim10, Dromel_CG9878_FBtr0071676_tim10_mORF, bs31d12.y1, CG9878, Tim10" "IPR027247=Mitochondrial import inner membrane translocase subunit Tim10/Tim12, IPR004217=Tim10/DDP family zinc finger" CG9878 16-Dec-15 2015_12 "ENSDARG00000069131,ENSDARG00000069116(timm10)" YHR005C-A(TIM10) WBGene00006573(tin-10) ENSXETG00000027231(timm10) ENSMUSG00000027076(Timm10) ENSG00000134809(TIMM10) "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0010358 ë«Try ë«Trypsin http://flybase.net/reports/FBgn0010358.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "0005829=cytosol, 0005576=extracellular region" "Try, endoproteinase I, DmDeltaTry, endo-I, deltaTry, CG12351, delta" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG12351 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" DRSC07622 K -0.973581622 -0.953210578 -0.534894881 -0.190095294 0.64368416 -1.845562255 FBgn0027372 RevIII-7y RevIII-7y http://flybase.net/reports/FBgn0027372.html gene 16-Dec-15 2015_12 FBgn0029722 CG7024 http://flybase.net/reports/FBgn0029722.html protein_coding_gene 0004739=pyruvate dehydrogenase (acetyl-transferring) activity "0055114=oxidation-reduction process, 0006096=glycolytic process" "0043231=intracellular membrane-bounded organelle, 0045254=pyruvate dehydrogenase complex" "IPR001017=Dehydrogenase, E1 component, IPR017597=Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y, IPR029061=Thiamin diphosphate-binding fold" CG7024 16-Dec-15 2015_12 YER178W(PDA1) viable FBgn0005206 l(3)DTS10 lethal (3) DTS10 http://flybase.net/reports/FBgn0005206.html gene DTS-10 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,female sterile" FBgn0010672 l(2)rJ235 lethal (2) rJ235 http://flybase.net/reports/FBgn0010672.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000864 fs(1)M58 female sterile (1) M58 http://flybase.net/reports/FBgn0000864.html gene 16-Dec-15 2015_12 "lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,recessive,heat sensitive,female sterile,some die during embryonic stage" egg FBgn0000471 Dly Delayed recovery http://flybase.net/reports/FBgn0000471.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0025674 CycK Cyclin K http://flybase.net/reports/FBgn0025674.html "FBan0015218, FBgn0032975" protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0019901=protein kinase binding" "0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG15218, cyclin K, CyclinK" "IPR004367=Cyclin, C-terminal domain, IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal, IPR015429=Cyclin C/H/T/L" CG15218 16-Dec-15 2015_12 ENSDARG00000034146(ccnk) WBGene00009650(F43D2.1) ENSXETG00000011438(CCNK) ENSMUSG00000021258(Ccnk) ENSG00000090061(CCNK) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC03714 I -0.670065037 1.622417665 -0.424427973 0.619542827 -0.303414208 -0.450708288 FBgn0003610 Su(var)209 Suppressor of variegation 209 http://flybase.net/reports/FBgn0003610.html gene 209 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable,non-suppressor of variegation" FBgn0086443 Aats-asn Asparaginyl-tRNA synthetase http://flybase.net/reports/FBgn0086443.html "FBgn0027092, FBgn0002029, FBgn0028492" protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004816=asparagine-tRNA ligase activity" 0006421=asparaginyl-tRNA aminoacylation 0005737=cytoplasm "l(2)37Ca)E11, lethal (2) 37Ca, Asparaginyl-tRNA synthetase, l(2)E11, NRS, l(2)37Ca, Ca, CG10687, AsnRS, BcDNA:GH06451" "IPR006195=Aminoacyl-tRNA synthetase, class II, IPR004365=OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR012340=Nucleic acid-binding, OB-fold, IPR018150=Aminoacyl-tRNA synthetase, class II (D/K/N)-like, IPR004522=Asparagine-tRNA ligase, IPR002312=Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR004364=Aminoacyl-tRNA synthetase, class II (D/K/N)" CG10687 16-Dec-15 2015_12 ENSDARG00000061100(si:dkey-274m14.2) YHR019C(DED81) WBGene00003815(nars-1) ENSXETG00000027170(NARS) ENSMUSG00000024587(Nars) ENSG00000134440(NARS) embryonic stage "

ubiquitous , embryonic/larval salivary gland

" FBgn0039563 CG4951 http://flybase.net/reports/FBgn0039563.html protein_coding_gene CG4951 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0000799 fs(1)de10 female sterile (1) defective eggs 10 http://flybase.net/reports/FBgn0000799.html gene de10 16-Dec-15 2015_12 "female sterile,recessive" dorsal appendage FBgn0266708 Cep89 Centrosomal protein 89kDa homolog http://flybase.net/reports/FBgn0266708.html "FBgn0266531, FBgn0034037" protein_coding_gene "0007268=synaptic transmission, 0007005=mitochondrion organization, 0046959=habituation" CG8214 CG8214 16-Dec-15 2015_12 ENSDARG00000005092(ccdc123) ENSXETG00000018269(CCDC123) ENSMUSG00000023072(Ccdc123) FBgn0015358 anon-9Bb anon-9Bb http://flybase.net/reports/FBgn0015358.html gene 16-Dec-15 2015_12 FBgn0035721 CG9948 http://flybase.net/reports/FBgn0035721.html protein_coding_gene IPR006578=MADF domain CG9948 16-Dec-15 2015_12 viable FBgn0051195 CG31195 http://flybase.net/reports/FBgn0051195.html FBgn0010818 protein_coding_gene 0005886=plasma membrane "l(3)03806, unnamed" CG31195 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065793 l(2)SH0420 lethal (2) SH0420 http://flybase.net/reports/FBgn0065793.html gene l(2)SH2 0420 16-Dec-15 2015_12 "lethal,recessive" FBgn0028705 Mtr1 Methyltransferase-related protein 1 http://flybase.net/reports/FBgn0028705.html gene "0000793=condensed chromosome, 0005737=cytoplasm" "DmMTR1, Drosophila melanogaster CpG MTase-related protein 1" 16-Dec-15 2015_12 FBgn0037061 CG12975 http://flybase.net/reports/FBgn0037061.html FBgn0047083 protein_coding_gene BcDNA:RE57810 IPR005651=Uncharacterised protein family UPF0434/Trm112 CG12975 16-Dec-15 2015_12 ENSDARG00000071878(zgc:110652) YNR046W(TRM112) WBGene00007312(C04H5.1) ENSXETG00000007218(TNeu118m06.1) "ENSMUSG00000038812(Trmt112),ENSMUSG00000057627(Trmt112-ps),ENSMUSG00000071762(Gm10346)" ENSG00000173113(TRMT112) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0035241 CG12105 http://flybase.net/reports/FBgn0035241.html protein_coding_gene CG12105 16-Dec-15 2015_12 viable FBgn0067101 GstD1::GstD2 GstD1::GstD2 http://flybase.net/reports/FBgn0067101.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0032647 CG15143 http://flybase.net/reports/FBgn0032647.html protein_coding_gene IPR026720=Protein MAATS1 CG15143 16-Dec-15 2015_12 ENSDARG00000006292(si:dkey-265i7.2) ENSXETG00000018054(C3orf15) ENSMUSG00000022805(4932425I24Rik) ENSG00000183833(C3orf15) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0051079 CG31079 http://flybase.net/reports/FBgn0051079.html protein_coding_gene 16-Dec-15 2015_12 "body color defective,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0265605 Ric Ras-related protein interacting with calmodulin http://flybase.net/reports/FBgn0265605.html "FBgn0017549, FBgn0015804" protein_coding_gene "0005516=calmodulin binding, 0005525=GTP binding, 0003924=GTPase activity" "0009408=response to heat, 0006970=response to osmotic stress, 0007264=small GTPase mediated signal transduction, 0042594=response to starvation, 0006979=response to oxidative stress" 0005886=plasma membrane "Ras which interacts with Calmodulin, Ras-related which interacted with Calmodulin, Ras operated by calmodulin, Roc, 17137290, RIC, Q7JMZ0, CG8418, D-Ric" "IPR020849=Small GTPase superfamily, Ras type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG8418 16-Dec-15 2015_12 ENSDARG00000069150(rit1) ENSXETG00000012434(RIT1) "ENSMUSG00000057455(Rit2),ENSMUSG00000028057(Rit1)" "ENSG00000152214(RIT2),ENSG00000143622(RIT1)" FBgn0259101 CG42249 http://flybase.net/reports/FBgn0259101.html "FBgn0030264, FBgn0030265" protein_coding_gene "0046872=metal ion binding, 0017111=nucleoside-triphosphatase activity, 0000166=nucleotide binding, 0008253=5'-nucleotidase activity, 0017110=nucleoside-diphosphatase activity" 0009166=nucleotide catabolic process "CG11126, CG1961" "IPR008334=5'-Nucleotidase, C-terminal, IPR029052=Metallo-dependent phosphatase-like, IPR006146=5'-Nucleotidase, conserved site, IPR006179=5'-Nucleotidase/apyrase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG42249 16-Dec-15 2015_12 FBgn0052175 CG32175 http://flybase.net/reports/FBgn0052175.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065107 snmRNA:128 small non-messenger RNA 128 http://flybase.net/reports/FBgn0065107.html FBgn0053915 non_protein_coding_gene "CR33915, Dm-128" CR33915 16-Dec-15 2015_12 FBgn0005408 l(1)11Ah lethal (1) 11Ah http://flybase.net/reports/FBgn0005408.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086291 GS5071 http://flybase.net/reports/FBgn0086291.html gene 5071 16-Dec-15 2015_12 FBgn0025877 opus\env env http://flybase.net/reports/FBgn0025877.html transposable_element_gene "env, yoyo\Env, yoyo\env, ORF3" 16-Dec-15 2015_12 FBgn0267757 CR46088 http://flybase.net/reports/FBgn0267757.html non_protein_coding_gene CR46088 16-Dec-15 2015_12 FBgn0036621 roq roquin http://flybase.net/reports/FBgn0036621.html FBgn0045222 protein_coding_gene "0008270=zinc ion binding, 0044822=poly(A) RNA binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination 0010494=cytoplasmic stress granule "CG16807, NEST:bs21b12" "IPR000571=Zinc finger, CCCH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR001841=Zinc finger, RING-type" CG16807 16-Dec-15 2015_12 "ENSDARG00000062550(rc3h1),ENSDARG00000063182(LOC558213),ENSDARG00000063050(si:ch211-243g18.1)" WBGene00010923(rle-1) "ENSMUSG00000075376(Rc3h2),ENSMUSG00000040423(Rc3h1)" "ENSG00000056586(RC3H2),ENSG00000135870(RC3H1)" "viable,fertile" FBgn0041257 E(Src64)2B E(Src64)2B http://flybase.net/reports/FBgn0041257.html gene 16-Dec-15 2015_12 FBgn0063757 CR32366 http://flybase.net/reports/FBgn0063757.html FBgn0052366 non_protein_coding_gene BcDNA:AT05287 16-Dec-15 2015_12 FBgn0051122 CG31122 http://flybase.net/reports/FBgn0051122.html "FBgn0038620, FBgn0038622" protein_coding_gene 0046331=lateral inhibition "CG14308, CG7687" IPR018881=Uncharacterised protein family UPF0565 CG31122 16-Dec-15 2015_12 ENSDARG00000062425(zgc:153521) ENSXETG00000018287(C2orf69) ENSMUSG00000038323(1700066M21Rik) ENSG00000178074(C2orf69) "viable,fertile,long lived,visible" "chaeta,supernumerary,trichogen cell" DRSC14787 IE -1.865577931 -4.524854393 -1.208602766 -5.085351401 -0.944574426 -0.6760163 FBgn0060397 l(3)S132214 lethal (3) S132214 http://flybase.net/reports/FBgn0060397.html gene 1322/14 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0052371 CG32371 http://flybase.net/reports/FBgn0052371.html "FBgn0024999, FBgn0045810" protein_coding_gene 0008017=microtubule binding 0015630=microtubule cytoskeleton "EB1, BEST:GH23475" "IPR001715=Calponin homology domain, IPR027328=Microtubule-associated protein RP/EB, IPR004953=EB1, C-terminal" CG32371 16-Dec-15 2015_12 YER016W(BIM1) viable FBgn0011017 l(3)s2017 lethal (3) s2017 http://flybase.net/reports/FBgn0011017.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264443 CG43861 http://flybase.net/reports/FBgn0264443.html "FBgn0032838, FBgn0040995" protein_coding_gene "CG13966, CG12508" CG43861 16-Dec-15 2015_12 FBgn0085457 CG34428 http://flybase.net/reports/FBgn0085457.html "FBan0014116, FBgn0036344" protein_coding_gene CG14116 IPR006631=Protein of unknown function DM4/12 CG34428 16-Dec-15 2015_12 viable FBgn0038108 CG7518 http://flybase.net/reports/FBgn0038108.html protein_coding_gene IPR029717=FAM193 family CG7518 16-Dec-15 2015_12 viable DRSC16253 I 1.666185537 -0.483092391 -0.169998659 -0.355073216 0.284368513 0.544138965 FBgn0263973 jv javelin http://flybase.net/reports/FBgn0263973.html "FBgn0001292, FBgn0052397, FBgn0044788" protein_coding_gene "0030046=parallel actin filament bundle assembly, 0008407=chaeta morphogenesis" 0032432=actin filament bundle "CG32397, anon-WO0138581.6" CG32397 16-Dec-15 2015_12 visible "denticle belt,macrochaeta,microchaeta,posterior scutellar bristle,actin filament bundle,nurse cell" FBgn0029013 l(3)77CDl lethal (3) 77CDl http://flybase.net/reports/FBgn0029013.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0002842 sa spermatocyte arrest http://flybase.net/reports/FBgn0002842.html FBgn0037080 protein_coding_gene "0007141=male meiosis I, 0048515=spermatid differentiation, 0007283=spermatogenesis, 0007286=spermatid development, 0007126=meiotic nuclear division, 0010468=regulation of gene expression" "0001673=male germ cell nucleus, 0005730=nucleolus" "CG11308, Sa, TAF8L, ms(3)sa, golfballs, TAF-like, gfb, spermatocytes arrest, tTAF, dTAF8L, testis-specific TBP Associated Factor, ms(3)VO45, ms(3)VO5" "IPR006565=Bromodomain associated domain, IPR019473=Transcription factor TFIID, subunit 8, C-terminal" CG11308 16-Dec-15 2015_12 "male sterile,recessive,meiotic cell cycle defective,viable" "testis,spermatocyte" FBgn0038420 CG10311 http://flybase.net/reports/FBgn0038420.html FBgn0043812 protein_coding_gene "BEST:GH22794, dmCG10311, gh22794" CG10311 16-Dec-15 2015_12 "viable,fertile" FBgn0003438 smd smalloid http://flybase.net/reports/FBgn0003438.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective,viable,fertile" eye FBgn0032775 CG17544 http://flybase.net/reports/FBgn0032775.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016402=pristanoyl-CoA oxidase activity, 0003997=acyl-CoA oxidase activity, 0003995=acyl-CoA dehydrogenase activity" 0006635=fatty acid beta-oxidation 0005777=peroxisome "IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR012258=Acyl-CoA oxidase, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR002655=Acyl-CoA oxidase, C-terminal, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain" CG17544 16-Dec-15 2015_12 YGL205W(POX1) WBGene00019060(F58F9.7) "viable,fertile" FBgn0037714 CG9396 http://flybase.net/reports/FBgn0037714.html protein_coding_gene 0050833=pyruvate transmembrane transporter activity 0006850=mitochondrial pyruvate transport "0016021=integral component of membrane, 0031305=integral component of mitochondrial inner membrane" IPR005336=Mitochondrial pyruvate carrier CG9396 16-Dec-15 2015_12 "ENSDARG00000024478(brp44),ENSDARG00000037679(zgc:103678)" "YHR162W(),YGR243W(FMP43)" WBGene00018765(F53F10.3) ENSXETG00000025716(brp44) ENSMUSG00000026568(Brp44) ENSG00000143158(BRP44) FBgn0067629 CG33332 http://flybase.net/reports/FBgn0067629.html "FBgn0038270, FBgn0053332, FBgn0069055" protein_coding_gene "CG3641, BcDNA:RE07395" IPR022226=Protein of unknown function DUF3752 CG33332 16-Dec-15 2015_12 ENSDARG00000058287(zgc:91844) WBGene00009145(F26A3.7) ENSXETG00000014779(KIAA1704) ENSMUSG00000022008(1200011I18Rik) ENSG00000133114(KIAA1704) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0001343 l(1)1Ca lethal (1) 1Ca http://flybase.net/reports/FBgn0001343.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,recessive" FBgn0036271 Pbgs Porphobilinogen synthase http://flybase.net/reports/FBgn0036271.html protein_coding_gene "0004655=porphobilinogen synthase activity, 0046872=metal ion binding" 0033014=tetrapyrrole biosynthetic process "delta-ALA-D, delta-aminolevulinate dehydratase, CG10335, DmPBGS" "IPR013785=Aldolase-type TIM barrel, IPR001731=Delta-aminolevulinic acid dehydratase, IPR030656=Delta-aminolevulinic acid dehydratase, active site" CG10335 16-Dec-15 2015_12 ENSDARG00000052815(alad) YGL040C(HEM2) ENSXETG00000023474(ALAD) ENSMUSG00000028393(Alad) ENSG00000148218(ALAD) "viable,lethal" FBgn0037470 Tailor Tailor http://flybase.net/reports/FBgn0037470.html FBgn0062161 protein_coding_gene 0050265=RNA uridylyltransferase activity "0031054=pre-miRNA processing, 0071076=RNA 3' uridylation" "anon-WO0118547.222, CG1091" IPR002058=PAP/25A-associated CG1091 16-Dec-15 2015_12 WBGene00003499(mut-2) ENSG00000149016(TUT1) viable FBgn0015375 cub currant bun http://flybase.net/reports/FBgn0015375.html FBgn0002025 gene "lethal(2)37Bg, l(2)37Bg, Bg" 16-Dec-15 2015_12 "wild-type,lethal,recessive" "melanotic mass,pupa,pupal cuticle,wing disc,ventral thoracic disc" FBgn0033355 CG13748 http://flybase.net/reports/FBgn0033355.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG13748 16-Dec-15 2015_12 ENSMUSG00000074596(Spint3) viable DRSC06419 I 1.879083553 -0.091678368 0.421111536 0.188996947 0.770909311 0.331354923 FBgn0263781 CG41057 http://flybase.net/reports/FBgn0263781.html "FBan0041057, FBgn0085560, FBgn0058157" protein_coding_gene CG40157 16-Dec-15 2015_12 FBgn0266561 EP2173 http://flybase.net/reports/FBgn0266561.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0014191 hobo\T hobo element transposase http://flybase.net/reports/FBgn0014191.html transposable_element_gene "0046983=protein dimerization activity, 0003677=DNA binding" "H\T, unnamed" "IPR012337=Ribonuclease H-like domain, IPR003656=Zinc finger, BED-type, IPR008906=HAT dimerisation domain, C-terminal, IPR018473=Hermes trasposase, DNA-binding domain" 16-Dec-15 2015_12 FBgn0050429 CG30429 http://flybase.net/reports/FBgn0050429.html protein_coding_gene Q8MLN3_DROME IPR003409=MORN motif CG30429 16-Dec-15 2015_12 ENSDARG00000021697 ENSMUSG00000029477(Morn3) ENSG00000139714(MORN3) viable FBgn0034105 CG7755 http://flybase.net/reports/FBgn0034105.html protein_coding_gene "0004449=isocitrate dehydrogenase (NAD+) activity, 0000287=magnesium ion binding, 0051287=NAD binding" "0055114=oxidation-reduction process, 0022416=chaeta development" 0005759=mitochondrial matrix "IPR024084=Isopropylmalate dehydrogenase-like domain, IPR001804=Isocitrate and isopropylmalate dehydrogenases family" CG7755 16-Dec-15 2015_12 viable FBgn0060677 l(3)S077213 lethal (3) S077213 http://flybase.net/reports/FBgn0060677.html gene 0772/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0026440 EY3-5 EY3-5 http://flybase.net/reports/FBgn0026440.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004824 fs(2)ltoPI23 female sterile (2) ltoPI23 http://flybase.net/reports/FBgn0004824.html gene 0048477=oogenesis Pl23 16-Dec-15 2015_12 FBgn0015410 l(1)14ABa lethal (1) 14ABa http://flybase.net/reports/FBgn0015410.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267690 CG46026 http://flybase.net/reports/FBgn0267690.html protein_coding_gene "mdcds_43655, CG31556" CG46026 16-Dec-15 2015_12 FBgn0060362 l(3)S138901b lethal (3) S138901b http://flybase.net/reports/FBgn0060362.html gene 1389/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0042680 Rt1b\gag gag http://flybase.net/reports/FBgn0042680.html transposable_element_gene "ORF1, Waldo-A\gag, Rt1b/gag" 16-Dec-15 2015_12 FBgn0033607 CG9062 http://flybase.net/reports/FBgn0033607.html protein_coding_gene "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR021772=Protein of unknown function DUF3337, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG9062 16-Dec-15 2015_12 ENSDARG00000038543(LOC100333793) YOL087C() WBGene00009441(F35G12.4) ENSXETG00000004247(WDR48) ENSMUSG00000032512(Wdr48) ENSG00000114742(WDR48) viable FBgn0264884 CR44075 http://flybase.net/reports/FBgn0264884.html non_protein_coding_gene CR44075 16-Dec-15 2015_12 FBgn0265159 CR44228 http://flybase.net/reports/FBgn0265159.html non_protein_coding_gene CR44228 16-Dec-15 2015_12 FBgn0031159 CG11566 http://flybase.net/reports/FBgn0031159.html "FBgn0031158, FBgn0052514, FBtr0077248, FBpp0076940, FBtr0077249, FBpp0076941" protein_coding_gene "CG32514, CG11569" CG11566 16-Dec-15 2015_12 "viable,fertile" FBgn0084638 su(eas)7 su(eas)7 http://flybase.net/reports/FBgn0084638.html gene 16-Dec-15 2015_12 viable FBgn0010786 l(3)02640 lethal (3) 02640 http://flybase.net/reports/FBgn0010786.html "FBgn0011370, FBgn0035212, FBgn0045880" protein_coding_gene 0004418=hydroxymethylbilane synthase activity "0018160=peptidyl-pyrromethane cofactor linkage, 0033014=tetrapyrrole biosynthetic process" "hydroxymethylbilane synthase, anon-WO0153538.70, porphobilinogen deaminase, l(3)7E130, CG9165, 3544, 2640, l(3)3544, PBGD, l(3)j4E3" "IPR022418=Porphobilinogen deaminase, C-terminal, IPR022417=Porphobilinogen deaminase, N-terminal, IPR022419=Porphobilinogen deaminase, dipyrromethane cofactor binding site, IPR000860=Porphobilinogen deaminase" CG9165 16-Dec-15 2015_12 "ENSDARG00000008840(hmbsa),ENSDARG00000055991(hmbsb)" YDL205C(HEM3) "lethal,viable,fertile,recessive" FBgn0052224 CR32224 http://flybase.net/reports/FBgn0052224.html non_protein_coding_gene CG32224 CR32224 16-Dec-15 2015_12 FBgn0034837 RpL22-like Ribosomal protein L22-like http://flybase.net/reports/FBgn0034837.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "rpL22-like, RpL22-like, CG9871, ribosomal protein L22-like" IPR002671=Ribosomal protein L22e CG9871 16-Dec-15 2015_12 DRSC04582 K -0.628549451 0.675142498 -0.444610541 -0.057231442 1.653236274 -0.953135268 FBgn0041727 Rt1a\gag gag http://flybase.net/reports/FBgn0041727.html FBgn0042677 transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "pilger\gag, Waldo-B\gag, ORF1" "IPR001878=Zinc finger, CCHC-type" 16-Dec-15 2015_12 FBgn0069156 mcl(3)Z2585 mcl(3)Z2585 http://flybase.net/reports/FBgn0069156.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0028947 CG11865 http://flybase.net/reports/FBgn0028947.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" 0006508=proteolysis "BG:BACR44L22.4, BACR44L22.4" "IPR001506=Peptidase M12A, astacin, IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain" CG11865 16-Dec-15 2015_12 viable FBgn0266557 kis kismet http://flybase.net/reports/FBgn0266557.html "FBgn0062647, FBgn0086902, FBgn0010642, FBgn0010689, FBgn0010697, FBgn0010698, FBgn0021918, FBgn0026596, FBgn0031234, FBgn0031236, FBgn0046436, FBgn0063789, FBgn0021813, FBgn0001309" protein_coding_gene "0008094=DNA-dependent ATPase activity, 0005524=ATP binding, 0008026=ATP-dependent helicase activity" "0016322=neuron remodeling, 1902685=positive regulation of receptor localization to synapse, 0046622=positive regulation of organ growth, 0007411=axon guidance, 0008340=determination of adult lifespan, 0007379=segment specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0040011=locomotion, 0007614=short-term memory, 0045892=negative regulation of transcription, DNA-templated, 0007350=blastoderm segmentation, 0007298=border follicle cell migration, 0008582=regulation of synaptic growth at neuromuscular junction, 0007476=imaginal disc-derived wing morphogenesis, 0019730=antimicrobial humoral response" "0005634=nucleus, 0005875=microtubule associated complex, 0005654=nucleoplasm" "anon-WO0257455.5, BEST:GM02209, CG3696, lethal (2) k16510, EK2-4, Su(Pc)21AB, unnamed, CG18326, Pex20, l(2)s3527, KIS, GM02209, kiss, 2532, EP(2)0474, FBtr0078144, anon-WO0172774.164, EP474, l(2)s4793, l(2)k16510, l(2)k08827, l(2)k14112, Kis, lethal (2) k11324, EC2-7, KIS-L, l(2)07812, 136/31, 5841, Kismet, DmelPex20, l(2)k13631, l(2)k11324, CG3660, l(2)s4771, Peroxin 20" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR006576=BRK domain, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like, IPR023780=Chromo domain, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain" CG3696 16-Dec-15 2015_12 ENSDARG00000017244(LOC570753) WBGene00007053(tag-192) "ENSXETG00000000349(CHD9),ENSXETG00000017194(CHD8),ENSXETG00000021445(CHD6)" "ENSMUSG00000041235(Chd7),ENSMUSG00000056608(Chd9),ENSMUSG00000057133(Chd6),ENSMUSG00000053754(Chd8)" "ENSG00000171316(CHD7),ENSG00000177200(CHD9),ENSG00000124177(CHD6),ENSG00000100888(CHD8)" DRSC00625 IK 1.083501426 -1.973909437 0.711314895 0.462711635 0.317857778 2.555470177 FBgn0031478 CG8814 http://flybase.net/reports/FBgn0031478.html protein_coding_gene "0050809=diazepam binding, 0000062=fatty-acyl-CoA binding, 0004857=enzyme inhibitor activity" 0042049=cellular acyl-CoA homeostasis "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000582=Acyl-CoA-binding protein, ACBP" CG8814 16-Dec-15 2015_12 "ENSDARG00000034883(acbd5a),ENSDARG00000058410(LOC100004736),ENSDARG00000027070(zgc:85611)" ENSXETG00000018777(BC082499.1) ENSMUSG00000026781(Acbd5) ENSG00000107897(ACBD5) "viable,fertile" FBgn0022320 l(1)B64.2 lethal (1) B64.2 http://flybase.net/reports/FBgn0022320.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040931 CG9034 http://flybase.net/reports/FBgn0040931.html FBgn0047012 protein_coding_gene "BcDNA:RH45008, GH20078" CG9034 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0069905 CR41115 http://flybase.net/reports/FBgn0069905.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0015256 M(2)92 M(2)92 http://flybase.net/reports/FBgn0015256.html gene 16-Dec-15 2015_12 "visible,dominant,Minute" FBgn0029096 ap::Chi ap::Chi http://flybase.net/reports/FBgn0029096.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing,ventral compartment,wing margin,ectopic,dorsal compartment" FBgn0050181 ppk3 pickpocket 3 http://flybase.net/reports/FBgn0050181.html FBgn0034874 protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "pickpocket 3, ppk3, cg30181, CG15872, CG30181" "IPR001873=Na+ channel, amiloride-sensitive" CG30181 16-Dec-15 2015_12 FBgn0040718 CG15353 http://flybase.net/reports/FBgn0040718.html FBgn0062918 protein_coding_gene BcDNA:RH63135 CG15353 16-Dec-15 2015_12 viable FBgn0086670 snoRNA:ë¬28S-2622 snoRNA:ë¬28S-2622 http://flybase.net/reports/FBgn0086670.html "FBgn0065069, FBgn0082984, FBgn0053656" snoRNA_gene 0005730=nucleolus "snoRNA:3, CR33656, Dm-3, Psi28S-2622(SnoR3), chr3L:1472428..1472587, snoR3, psi28s-2622" CR33656 16-Dec-15 2015_12 FBgn0032593 Trpë_ Transient receptor potential cation channel ë_ http://flybase.net/reports/FBgn0032593.html protein_coding_gene "0005262=calcium channel activity, 0005515=protein binding, 0005261=cation channel activity" "0070588=calcium ion transmembrane transport, 0006816=calcium ion transport, 0009416=response to light stimulus, 0006812=cation transport, 0050908=detection of light stimulus involved in visual perception" "0016028=rhabdomere, 0034703=cation channel complex, 0034704=calcium channel complex" "dTRPg, DmTRPgamma, dTRPgamma, trp-gamma, Trpgamma, Trp-gamma, TRPgamma, trpgamma, CG5996" "IPR002153=Transient receptor potential channel, canonical, IPR004729=Transient receptor potential channel, IPR029877=Transient receptor potential-gamma protein, IPR005821=Ion transport domain, IPR013555=Transient receptor ion channel domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG5996 16-Dec-15 2015_12 "ENSDARG00000062183(LOC566436),ENSDARG00000070504,ENSDARG00000070507(LOC555897),ENSDARG00000060837" WBGene00006615(trp-2) "ENSXETG00000001811(TRPC4),ENSXETG00000012403(TRPC5)" "ENSMUSG00000027748(Trpc4),ENSMUSG00000041710(Trpc5)" "ENSG00000133107(TRPC4),ENSG00000072315(TRPC5)" "partially lethal - majority die,some die during pupal stage,viable,lethal" FBgn0036096 CG8003 http://flybase.net/reports/FBgn0036096.html protein_coding_gene 0008270=zinc ion binding "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR002893=Zinc finger, MYND-type" CG8003 16-Dec-15 2015_12 "ENSDARG00000005948(ankmy2a),ENSDARG00000035919" WBGene00021659(Y48G1A.3) ENSXETG00000022796(ANKMY2) ENSMUSG00000036188(Ankmy2) ENSG00000106524(ANKMY2) "partially lethal - majority die,some die during pupal stage" FBgn0022108 l(2)k07005 lethal (2) k07005 http://flybase.net/reports/FBgn0022108.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0063421 l(3)3450-B lethal (3) 3450-B http://flybase.net/reports/FBgn0063421.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0032481 CG16972 http://flybase.net/reports/FBgn0032481.html FBgn0044577 protein_coding_gene anon-WO0140519.52 CG16972 16-Dec-15 2015_12 viable rhabdomere R7 FBgn0051683 CG31683 http://flybase.net/reports/FBgn0051683.html "FBgn0027612, FBgn0063627" protein_coding_gene "0008374=O-acyltransferase activity, 0004620=phospholipase activity" 0006629=lipid metabolic process BcDNA:GH02384 "IPR003386=Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase, IPR029058=Alpha/Beta hydrolase fold" CG31683 16-Dec-15 2015_12 "ENSDARG00000010587,ENSDARG00000062375" WBGene00010872(M05B5.4) ENSXETG00000005810(PLA2G15) "ENSMUSG00000031903(Pla2g15),ENSMUSG00000035237(Lcat)" "ENSG00000103066(PLA2G15),ENSG00000213398(LCAT)" FBgn0050476 ave aveugle http://flybase.net/reports/FBgn0050476.html FBgn0064863 protein_coding_gene "0007173=epidermal growth factor receptor signaling pathway, 0007165=signal transduction, 0001751=compound eye photoreceptor cell differentiation, 0042675=compound eye cone cell differentiation, 0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction" "0005886=plasma membrane, 0005737=cytoplasm" "Hyphen, HYP, CG30476/Ave, hyp, BcDNA:RE67675, CG30476" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG30476 16-Dec-15 2015_12 WBGene00044341(ave-1) ENSMUSG00000058656(Samd12) "increased cell death,somatic clone,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,viable" "photoreceptor cell R1,somatic clone,photoreceptor cell R6,photoreceptor cell R4,photoreceptor cell R3,cone cell,wing vein,wing disc" DRSC05502 IEK -0.783151309 -4.087557387 -0.368421198 -3.574424588 -1.561886618 -1.297273331 FBgn0260383 GSd319 http://flybase.net/reports/FBgn0260383.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0085509 CG40709 http://flybase.net/reports/FBgn0085509.html FBan0040709 protein_coding_gene 16-Dec-15 2015_12 FBgn0051344 CG31344 http://flybase.net/reports/FBgn0051344.html "FBgn0038305, FBgn0061805" protein_coding_gene 0022008=neurogenesis "anon-WO0118547.636, CG6572" IPR018713=Domain of unknown function DUF2236 CG31344 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0051206 CG31206 http://flybase.net/reports/FBgn0051206.html FBgn0045278 protein_coding_gene NEST:bs16c12 CG31206 16-Dec-15 2015_12 viable FBgn0000234 btdl buttonhead like http://flybase.net/reports/FBgn0000234.html gene 0001700=embryonic development via the syncytial blastoderm btd-l 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,semidominant" "embryonic head,cephalopharyngeal skeleton,adult head" FBgn0039305 CG11858 http://flybase.net/reports/FBgn0039305.html FBgn0046998 protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity BcDNA:RH66629 "IPR000297=Peptidyl-prolyl cis-trans isomerase, PpiC-type" CG11858 16-Dec-15 2015_12 "ENSDARG00000004527(zgc:110008),ENSDARG00000071577" WBGene00012996(Y48C3A.16) ENSXETG00000022578(pin4) "ENSMUSG00000056836(Gm6851),ENSMUSG00000079480(Pin4)" ENSG00000102309(PIN4) viable FBgn0262098 CG42851 http://flybase.net/reports/FBgn0262098.html protein_coding_gene chr2R_20696695_20697629.0 CG42851 16-Dec-15 2015_12 FBgn0037294 CG12590 http://flybase.net/reports/FBgn0037294.html protein_coding_gene CG12590 16-Dec-15 2015_12 FBgn0010417 Taf6 TBP-associated factor 6 http://flybase.net/reports/FBgn0010417.html "FBgn0011301, FBgn0016734, FBgn0052211" protein_coding_gene "0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0046982=protein heterodimerization activity" "0051090=regulation of sequence-specific DNA binding transcription factor activity, 0022008=neurogenesis, 0006366=transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0006367=transcription initiation from RNA polymerase II promoter, 0007221=positive regulation of transcription of Notch receptor target" "0005634=nucleus, 0005669=transcription factor TFIID complex" "Taf60, p62, dTAF[[II]]62, TBP-associated factor 60, dme-TAFII60, TAF, TAFII60, dTAFII62, Suppressor of Ras85D 3-4B, TAF[[II]]60, Taf-6, TFIID, Taf[[II]]60, dTAF[[II]]60, l(3)76BDf, TAFII60(62), TAF[[II]]60/62, TAF60, TFIID 62, TAF60/62, dmTAF6, TBP associated factor 60, taf6, d60, taf60, TAF[[II]], dTAF6, TAFII62, Taf62, TAF6, TAF[[II]]62, CG9348, dTAF[[II]]262, TBP-associated factor 60kD, SR3-4B, TBP-Associated Factor 6, dTAF62, CG32211, TBP-associated factor" "IPR011442=TAF6, C-terminal HEAT repeat domain, IPR011989=Armadillo-like helical, IPR009072=Histone-fold, IPR004823=TATA box binding protein associated factor (TAF), IPR016024=Armadillo-type fold" CG32211 16-Dec-15 2015_12 ENSDARG00000029135(taf6) YGL112C(TAF6) WBGene00006387(taf-6.1) ENSXETG00000004009(TAF6) ENSMUSG00000036980(Taf6) ENSG00000106290(TAF6) "lethal - all die before end of larval stage,some die during larval stage,melanotic mass phenotype,visible,male sterile,female sterile,lethal,recessive,decreased cell number,somatic clone,germline clone,cell lethalcell lethal,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "melanotic mass,eye,ommatidium,eye photoreceptor cell,supernumerary,rhabdomere,wing,testis,primary spermatocyte,dorsal appendage,egg,chorion,spermatocyte,embryonic/larval brain,somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC11299 I -1.76377163 0.324403927 -1.067379642 0.233869396 0.382784172 0.348969329 FBgn0037533 CD98hc CD98 heavy chain http://flybase.net/reports/FBgn0037533.html protein_coding_gene "0043169=cation binding, 0003824=catalytic activity" "0060356=leucine import, 0005975=carbohydrate metabolic process" 0005886=plasma membrane "RE39378p, CG2791, cd98hc" "IPR017853=Glycoside hydrolase superfamily, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR015902=Glycoside hydrolase, family 13" CG2791 16-Dec-15 2015_12 "ENSDARG00000037012(zgc:55813),ENSDARG00000036427(slc3a2),ENSDARG00000055791(zgc:158423)" "viable,fertile" FBgn0030530 jub Ajuba LIM protein http://flybase.net/reports/FBgn0030530.html protein_coding_gene "0016922=ligand-dependent nuclear receptor binding, 0003779=actin binding, 0008270=zinc ion binding, 0046966=thyroid hormone receptor binding" "0007067=mitotic nuclear division, 0071539=protein localization to centrosome, 0046622=positive regulation of organ growth, 0045572=positive regulation of imaginal disc growth, 0035329=hippo signaling" "0045179=apical cortex, 0000242=pericentriolar material, 0005911=cell-cell junction, 0005912=adherens junction, 0045177=apical part of cell" "Ajuba, djub, CG11063, Jub, Drosophila Ajuba LIM protein" "IPR001781=Zinc finger, LIM-type" CG11063 16-Dec-15 2015_12 ENSDARG00000063666(si:ch211-79l17.3) ENSMUSG00000022178(Jub) ENSG00000142279(WTIP) "lethal,viable,decreased cell growth,somatic clone,mitotic cell cycle defective,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,size defective,decreased cell number,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell number,fertile,visible" "centrosome | somatic clone,spindle | somatic clone,neuroblast,somatic clone,wing,wing blade,eye | pupal stage,eye" DRSC19367 K -1.499854418 -1.119289298 -0.772691664 -0.771390149 1.437404306 1.834838305 FBgn0264896 CR44087 http://flybase.net/reports/FBgn0264896.html non_protein_coding_gene CR44087 16-Dec-15 2015_12 FBgn0062695 EP1230 EP1230 http://flybase.net/reports/FBgn0062695.html gene EP(3)1230 16-Dec-15 2015_12 FBgn0000717 fo folded http://flybase.net/reports/FBgn0000717.html gene 16-Dec-15 2015_12 visible "wing,haltere,posterior scutellar bristle" FBgn0065865 l(2)SH0266 lethal (2) SH0266 http://flybase.net/reports/FBgn0065865.html gene l(2)SH2 0266 16-Dec-15 2015_12 "lethal,recessive" FBgn0267195 CR45635 http://flybase.net/reports/FBgn0267195.html non_protein_coding_gene lincRNA.790 CR45635 16-Dec-15 2015_12 FBgn0053879 His4:CG33879 His4:CG33879 http://flybase.net/reports/FBgn0053879.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33879 "IPR019809=Histone H4, conserved site, IPR009072=Histone-fold, IPR001951=Histone H4" CG33879 16-Dec-15 2015_12 "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) FBgn0010132 l(1)tsW3 lethal (1) tsW3 http://flybase.net/reports/FBgn0010132.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0260093 2L3090 http://flybase.net/reports/FBgn0260093.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0062607 Mod(var)1356 Mod(var)1356 http://flybase.net/reports/FBgn0062607.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1356 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0031945 CG7191 http://flybase.net/reports/FBgn0031945.html "FBtr0079485, FBpp0079108" protein_coding_gene CG7191 16-Dec-15 2015_12 "viable,fertile" FBgn0035931 CG13312 http://flybase.net/reports/FBgn0035931.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13312 16-Dec-15 2015_12 viable FBgn0033381 GstE13 Glutathione S transferase E13 http://flybase.net/reports/FBgn0033381.html FBgn0063153 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "BcDNA:LD22317, gste13, CG11784, GSTE13" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG11784 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0083003 snoRNA:ë¬28S-1175c snoRNA:ë¬28S-1175c http://flybase.net/reports/FBgn0083003.html snoRNA_gene "psi28s-1175c, CR34560" CR34560 16-Dec-15 2015_12 FBgn0259246 brp bruchpilot http://flybase.net/reports/FBgn0259246.html "FBgn0086376, FBgn0083982, FBgn0027377, FBgn0033418, FBgn0033420, FBgn0050336, FBgn0050337, FBgn0033419" protein_coding_gene 0005262=calcium channel activity "0048789=cytoskeletal matrix organization at active zone, 0007614=short-term memory, 0007268=synaptic transmission, 0007274=neuromuscular synaptic transmission, 0007269=neurotransmitter secretion, 0048790=maintenance of presynaptic active zone structure, 0008344=adult locomotory behavior, 0048167=regulation of synaptic plasticity, 0007615=anesthesia-resistant memory" "0042734=presynaptic membrane, 0031594=neuromuscular junction, 0048786=presynaptic active zone, 0048788=presynaptic cytoskeletal matrix assembled at active zones" "Brp, BRUCHPILOT, nc82, nc-82, CG30337, CG30336, Mabnc82, Bruchpilot, Monoclonal antibody nc82, BRP, Nc82, CG1931, CG12933, Burchpilot, CG42344, mAb nc82, bruchpilot, Cast, CG12932, mAbnc82, NC82, CG34146, MAbnc82" IPR019323=Active zone protein ELKS CG42344 16-Dec-15 2015_12 ENSXETG00000000929(ERC2) FBgn0053704 CG33704 http://flybase.net/reports/FBgn0053704.html "FBgn0045128, FBgn0045149, FBgn0045166, FBgn0045307, FBgn0045407" protein_coding_gene "NEST:bs27f10, NEST:bs05b09, bs30h04.y1, NEST:bs29a11, NEST:bs30h04, NEST:bs14b07" CG33704 16-Dec-15 2015_12 FBgn0001513 l(1)10Fg lethal (1) 10Fg http://flybase.net/reports/FBgn0001513.html gene "18, l(1)L18" 16-Dec-15 2015_12 lethal FBgn0001956 l(2)28Bb lethal (2) 28Bb http://flybase.net/reports/FBgn0001956.html gene "Complementation group N, N" 16-Dec-15 2015_12 "lethal,recessive" FBgn0083316 E(smoDN)1131 Enhancer of smoDN 1131 http://flybase.net/reports/FBgn0083316.html gene 16-Dec-15 2015_12 FBgn0030001 cyr cypher http://flybase.net/reports/FBgn0030001.html FBgn0030002 protein_coding_gene 0003382=epithelial cell morphogenesis 0016021=integral component of membrane "CG15338, CG15335, cyr, cypher" IPR001507=Zona pellucida domain CG15335 16-Dec-15 2015_12 WBGene00021396(cutl-24) "viable,fertile" FBgn0036897 CG8786 http://flybase.net/reports/FBgn0036897.html FBgn0063208 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0072572=poly-ADP-D-ribose binding, 0008270=zinc ion binding" "0031648=protein destabilization, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process" 0005829=cytosol "RNF146, BcDNA:GM01527, DRNF146" "IPR018123=WWE domain, subgroup, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR001841=Zinc finger, RING-type, IPR004170=WWE domain" CG8786 16-Dec-15 2015_12 "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024973 CG2701 http://flybase.net/reports/FBgn0024973.html FBgn0020598 protein_coding_gene "Coding Region II, EG:95B7.9, II, anon-3Bd, transcript II" "IPR003892=Ubiquitin system component Cue, IPR009060=UBA-like" CG2701 16-Dec-15 2015_12 ENSDARG00000013058(ascc2) ENSXETG00000016423(ASCC2) ENSMUSG00000020412(Ascc2) ENSG00000100325(ASCC2) viable FBgn0013598 l(3)B3-3-21 lethal (3) B3-3-21 http://flybase.net/reports/FBgn0013598.html gene 16-Dec-15 2015_12 lethal FBgn0260269 GSd217 http://flybase.net/reports/FBgn0260269.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0261638 CR42721 http://flybase.net/reports/FBgn0261638.html non_protein_coding_gene CR42721 16-Dec-15 2015_12 FBgn0085554 CG41015 http://flybase.net/reports/FBgn0085554.html FBan0041015 protein_coding_gene 16-Dec-15 2015_12 FBgn0003408 Sil Skilike http://flybase.net/reports/FBgn0003408.html gene 16-Dec-15 2015_12 "partially lethal - majority live,visible,semidominant" wing FBgn0065516 l(2)SH1142 lethal (2) SH1142 http://flybase.net/reports/FBgn0065516.html gene l(2)SH2 1142 16-Dec-15 2015_12 "lethal,recessive" FBgn0031461 daw dawdle http://flybase.net/reports/FBgn0031461.html protein_coding_gene "0005160=transforming growth factor beta receptor binding, 0008083=growth factor activity" "0050796=regulation of insulin secretion, 0007179=transforming growth factor beta receptor signaling pathway, 0040007=growth, 0032927=positive regulation of activin receptor signaling pathway, 0008340=determination of adult lifespan, 0007411=axon guidance, 0032924=activin receptor signaling pathway, 0010507=negative regulation of autophagy" "Alp23B, Alp23b, ALP23B, DAW, Activin like protein, CG16987, Activin Like Protein at 23B, Alp, cg16987, Activin-Like Protein, Dawdle, dActivin2, Daw" "IPR017948=Transforming growth factor beta, conserved site, IPR015615=Transforming growth factor-beta-related, IPR029034=Cystine-knot cytokine, IPR001839=Transforming growth factor-beta, C-terminal, IPR001111=Transforming growth factor-beta, N-terminal" CG16987 16-Dec-15 2015_12 WBGene00000936(dbl-1) "neuroanatomy defective,hypoactive,uncoordinated,lethal - all die before end of pupal stage,some die during pupal stage,partially,partially lethal - majority die,some die during larval stage,long lived,flight defective,progressive,RU486 conditional,viable,melanotic mass phenotype,circadian rhythm defective,heat sensitive" "intersegmental nerve,abdominal segmental nerve,intersegmental nerve branch ISNb of A1-7,embryonic/larval optic lobe,axon & eye photoreceptor cell,embryonic/larval anal pad,adult somatic muscle,progressive,lysosome | progressiveMhc.PW,autophagic vacuoleMhc.PW,melanotic mass,leg,bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" DRSC00479 I -0.422886708 1.586324583 -0.497186904 0.011384592 -0.488070278 -0.522160377 FBgn0267984 CR46251 http://flybase.net/reports/FBgn0267984.html non_protein_coding_gene CR46251 16-Dec-15 2015_12 FBgn0034999 CG3394 http://flybase.net/reports/FBgn0034999.html protein_coding_gene "0005324=long-chain fatty acid transporter activity, 0003824=catalytic activity" 0008152=metabolic process "IPR020845=AMP-binding, conserved site, IPR000873=AMP-dependent synthetase/ligase, IPR025110=AMP-binding enzyme C-terminal domain" CG3394 16-Dec-15 2015_12 YBR041W(FAT1) "WBGene00017012(acs-22),WBGene00009218(acs-20)" "ENSXETG00000023888(),ENSXETG00000016111(Q4QQR1_XENTR),ENSXETG00000008282(SLC27A6)" viable DRSC04366 K 0.036404441 -0.475948389 -0.213946908 0.463946247 0.380184075 1.919134013 FBgn0243501 l(2)CB05177 http://flybase.net/reports/FBgn0243501.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0263963 BG01878 http://flybase.net/reports/FBgn0263963.html gene 16-Dec-15 2015_12 "long lived,female limited,starvation stress response defective,gravitaxis defective,male limited" FBgn0038551 CG7357 http://flybase.net/reports/FBgn0038551.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7357 16-Dec-15 2015_12 WBGene00004335(ref-2) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0052865 ë±ë_-element:CR32865 ë±ë_-element:CR32865 http://flybase.net/reports/FBgn0052865.html non_protein_coding_gene "alphagamma-element:CR32865, CR32865" CR32865 16-Dec-15 2015_12 FBgn0266451 fau fau http://flybase.net/reports/FBgn0266451.html "FBgn0020439, FBgn0063173, FBgn0266447" protein_coding_gene 0034059=response to anoxia "CG6544, BcDNA:HL07933, CG45077, Fau" CG45077 16-Dec-15 2015_12 FBgn0010876 l(3)05820 lethal (3) 05820 http://flybase.net/reports/FBgn0010876.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002093 l(2)57Bc lethal (2) 57Bc http://flybase.net/reports/FBgn0002093.html gene 16-Dec-15 2015_12 lethal FBgn0259631 B0611 http://flybase.net/reports/FBgn0259631.html gene 16-Dec-15 2015_12 visible "anterior crossvein,tarsal segment,unguis,leg,arista" FBgn0001741 l(1)HM11 lethal (1) HM11 http://flybase.net/reports/FBgn0001741.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0025486 l(3)82Eb lethal (3) 82Eb http://flybase.net/reports/FBgn0025486.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" FBgn0051836 CG31836 http://flybase.net/reports/FBgn0051836.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267919 CR46200 http://flybase.net/reports/FBgn0267919.html non_protein_coding_gene lincRNA.412 CR46200 16-Dec-15 2015_12 FBgn0065659 l(2)SH0715 lethal (2) SH0715 http://flybase.net/reports/FBgn0065659.html gene l(2)SH2 0715 16-Dec-15 2015_12 "lethal,recessive" FBgn0040262 Ugt36Ba Ugt36Ba http://flybase.net/reports/FBgn0040262.html FBgn0032604 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "AC 005121A, CG13270" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG13270 16-Dec-15 2015_12 "WBGene00011006(ugt-47),WBGene00011564(ugt-50),WBGene00015141(ugt-46),WBGene00015965(ugt-48),WBGene00007070(ugt-49)" viable FBgn0259303 C488 http://flybase.net/reports/FBgn0259303.html gene 16-Dec-15 2015_12 "visible,lethal" "wing vein,chaeta,ectopic" FBgn0032654 CG15147 http://flybase.net/reports/FBgn0032654.html protein_coding_gene CG15147 16-Dec-15 2015_12 viable FBgn0069210 kek1::kek2 kek1::kek2 http://flybase.net/reports/FBgn0069210.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,partially,visible" "chorion,eye,ommatidium" FBgn0038391 GATAe GATAe http://flybase.net/reports/FBgn0038391.html protein_coding_gene "0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding" "0010629=negative regulation of gene expression, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007492=endoderm development, 0019730=antimicrobial humoral response, 0007494=midgut development" 0005634=nucleus "CG10278, dGATAe, dGATA-E, CG10278-PA" "IPR028436=Transcription factor GATA-4, IPR000679=Zinc finger, GATA-type, IPR013088=Zinc finger, NHR/GATA-type" CG10278 16-Dec-15 2015_12 YER040W(GLN3) "viable,visible" mesothoracic tergum FBgn0040279 Osi14 Osiris 14 http://flybase.net/reports/FBgn0040279.html "FBgn0037423, FBgn0040495" protein_coding_gene 0005887=integral component of plasma membrane "osi14, Osiris, BEST:LD24139, SP558, CG1155, Sp558" IPR012464=Protein of unknown function DUF1676 CG1155 16-Dec-15 2015_12 FBgn0283450 Glo1 Glyoxalase 1 http://flybase.net/reports/FBgn0283450.html "FBgn0028432, FBgn0033162" protein_coding_gene "0004462=lactoylglutathione lyase activity, 0046872=metal ion binding" "glo1, CG1707" "IPR029068=Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase, IPR004361=Glyoxalase I, IPR018146=Glyoxalase I, conserved site, IPR004360=Glyoxalase/fosfomycin resistance/dioxygenase domain" CG1707 16-Dec-15 2015_12 "ENSDARG00000068978(glo1),ENSDARG00000027860" ENSXETG00000010758(GLO1) ENSMUSG00000024026(Glo1) ENSG00000124767(GLO1) "viable,visible" trichogen cell FBgn0019894 anon-2Bc anon-2Bc http://flybase.net/reports/FBgn0019894.html gene unnamed 16-Dec-15 2015_12 FBgn0017624 Eig76Ea Eig76Ea http://flybase.net/reports/FBgn0017624.html gene "Ecdysone-induced gene 76E, Eig76-1" 16-Dec-15 2015_12 FBgn0000477 DNaseII Deoxyribonuclease II http://flybase.net/reports/FBgn0000477.html FBgn0038563 protein_coding_gene 0004531=deoxyribonuclease II activity "0006308=DNA catabolic process, 0045476=nurse cell apoptotic process, 0006259=DNA metabolic process" "dnaseII, DNase-1, acid DNase, DNase 1, DNase, DNase1, dnaseII[lo], CG7780, dDNase II, Deoxyribonuclease 1" IPR004947=Deoxyribonuclease II CG7780 16-Dec-15 2015_12 WBGene00003828(nuc-1) "ENSXETG00000025076(dnase2b),ENSXETG00000007923(dnase2)" "ENSMUSG00000003812(Dnase2a),ENSMUSG00000028185(Dnase2b)" "ENSG00000105612(DNASE2),ENSG00000137976(DNASE2B)" "electrophoretic variant,viable,cell death defective,semi-fertile,increased cell death,conditional,germline clone" "ovary,egg chamber,conditional,nurse cell,nucleus | oogenesis stage S14,germline clone,nucleus | germline clone | oogenesis stage S14" FBgn0001628 l(1)dn5 lethal (1) discs normal 5 http://flybase.net/reports/FBgn0001628.html gene l(1)d.norm.-5 16-Dec-15 2015_12 lethal FBgn0041591 l(3)S052908a lethal (3) S052908a http://flybase.net/reports/FBgn0041591.html gene "l(3)S052908, 0529/08, 529.08" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" presumptive embryonic/larval nervous system FBgn0060652 l(3)S083311 lethal (3) S083311 http://flybase.net/reports/FBgn0060652.html gene 0833/11 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0015983 l(2)PC4-K lethal (2) PC4-K http://flybase.net/reports/FBgn0015983.html gene l(2)PC4-L 16-Dec-15 2015_12 "lethal,recessive" FBgn0262168 ind::Drer\gsx1 http://flybase.net/reports/FBgn0262168.html engineered_fusion_gene "IndGsh1, Gind, ind::Brer\gsx1" 16-Dec-15 2015_12 FBgn0069193 l(3)DJ688 lethal (3) DJ688 http://flybase.net/reports/FBgn0069193.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001040 fs(3)H172 female sterile (3) H172 http://flybase.net/reports/FBgn0001040.html gene 16-Dec-15 2015_12 female sterile oocyte FBgn0038034 Cyp9f3ë¬ Cyp9f3ë¬ http://flybase.net/reports/FBgn0038034.html FBgn0061351 pseudogene_attribute "Cyp9f3p, CR17875, CG17875, 9f3p, Cyp9f3" CR17875 16-Dec-15 2015_12 DRSC25711 K -0.165384357 0.138898596 -0.537593954 0.112713843 -0.68411392 -1.577435914 FBgn0000857 fs(1)M51 female sterile (1) M51 http://flybase.net/reports/FBgn0000857.html gene 16-Dec-15 2015_12 female sterile chorion FBgn0085718 CG41600 http://flybase.net/reports/FBgn0085718.html FBan0041600 protein_coding_gene 16-Dec-15 2015_12 FBgn0260262 GSd449 http://flybase.net/reports/FBgn0260262.html gene 16-Dec-15 2015_12 lethal FBgn0030432 CG4404 http://flybase.net/reports/FBgn0030432.html protein_coding_gene 0003677=DNA binding "IPR004210=BESS motif, IPR006578=MADF domain" CG4404 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" "chaeta,supernumerary,trichogen cell" FBgn0030039 CG12123 http://flybase.net/reports/FBgn0030039.html protein_coding_gene CG12123 16-Dec-15 2015_12 "viable,fertile,body color defective" mesothoracic tergum DRSC17818 K 0.406728332 0.042875329 -0.324007984 -0.664236012 0.415530341 4.381010251 FBgn0259334 C935 http://flybase.net/reports/FBgn0259334.html gene 16-Dec-15 2015_12 visible wing hair FBgn0037750 Whamy http://flybase.net/reports/FBgn0037750.html protein_coding_gene "0051020=GTPase binding, 0003779=actin binding" "0001578=microtubule bundle formation, 0030036=actin cytoskeleton organization" "0005739=mitochondrion, 0005634=nucleus" "CG12946, Whamy" "IPR003124=WH2 domain, IPR028293=Verprolin" CG12946 16-Dec-15 2015_12 "viable,fertile" FBgn0261064 Rbsn-5 Rabenosyn-5 http://flybase.net/reports/FBgn0261064.html "FBgn0031991, FBgn0260563" protein_coding_gene "0046872=metal ion binding, 0005515=protein binding, 0031267=small GTPase binding" "0048227=plasma membrane to endosome transport, 0006897=endocytosis, 0045451=pole plasm oskar mRNA localization, 0030100=regulation of endocytosis, 0035088=establishment or maintenance of apical/basal cell polarity, 0008103=oocyte microtubule cytoskeleton polarization, 0001737=establishment of imaginal disc-derived wing hair orientation, 0034058=endosomal vesicle fusion" "0005768=endosome, 0005769=early endosome" "early endosomal antigen 1, rbsn-5, Rabenosyn-5, CG8506, Rbsn, MENE(2L)-C, EEA1, rabenosyn, MENE (2L)-C, Rbsn5, Rabenosyn5, rbsn, Rabenosyn, dRabenosyn" "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR015880=Zinc finger, C2H2-like, IPR000306=FYVE zinc finger, IPR021565=Rabenosyn, Rab binding domain, IPR007087=Zinc finger, C2H2, IPR017455=Zinc finger, FYVE-related" CG8506 16-Dec-15 2015_12 YDR323C(PEP7) WBGene00021538(rabs-5) ENSXETG00000004811(ZFYVE20) ENSMUSG00000014550(Zfyve20) ENSG00000131381(ZFYVE20) FBgn0011614 l(1)I33f18 lethal (1) I33f18 http://flybase.net/reports/FBgn0011614.html FBgn0010206 gene l(1)33f18 16-Dec-15 2015_12 lethal FBgn0034720 Liprin-ë_ Liprin-ë_ http://flybase.net/reports/FBgn0034720.html protein_coding_gene "0042803=protein homodimerization activity, 0005515=protein binding" "0007412=axon target recognition, 0045886=negative regulation of synaptic growth at neuromuscular junction" 0043234=protein complex "Liprin-gamma, CG11206, liprin gamma, Liprin CG11206, liprin-gamma" "IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain" CG11206 16-Dec-15 2015_12 ENSG00000189337(KAZN) "viable,fertile" FBgn0261604 M(3)80F Minute (3) 80F http://flybase.net/reports/FBgn0261604.html gene 16-Dec-15 2015_12 FBgn0029081 iab-7PRE iab-7 Polycomb group response element http://flybase.net/reports/FBgn0029081.html regulatory_region 0016458=gene silencing "Fab7 PRE, iab-7-PRE, iab, Fab7, iab-7 PRE" 16-Dec-15 2015_12 eye FBgn0260111 2L2084 http://flybase.net/reports/FBgn0260111.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0032346 Csl4 Csl4 http://flybase.net/reports/FBgn0032346.html protein_coding_gene "0000175=3'-5'-exoribonuclease activity, 0003723=RNA binding" "0006397=mRNA processing, 0010468=regulation of gene expression" "0035327=transcriptionally active chromatin, 0005737=cytoplasm, 0000177=cytoplasmic exosome (RNase complex), 0000176=nuclear exosome (RNase complex)" "CG6249, dCsl4, CSL4" "IPR019495=Exosome complex component CSL4, IPR025721=Exosome complex component, N-terminal domain, IPR012340=Nucleic acid-binding, OB-fold, IPR022967=RNA-binding domain, S1" CG6249 16-Dec-15 2015_12 ENSDARG00000059841(exosc1) YNL232W(CSL4) WBGene00012966(exos-1) ENSXETG00000003434(EXOSC1) ENSMUSG00000034321(Exosc1) ENSG00000171311(EXOSC1) "visible,partially lethal - majority die,some die during pupal stage,female sterile" mesothoracic tergum FBgn0024665 l(2)k05636 lethal (2) k05636 http://flybase.net/reports/FBgn0024665.html gene 56/36 16-Dec-15 2015_12 "lethal,recessive" FBgn0034372 Gint3 GDI interacting protein 3 http://flybase.net/reports/FBgn0034372.html protein_coding_gene 0005515=protein binding "Dromel_CG5469_FBtr0086654_gint3_mORF, UBX 6 like, CG5469" "IPR029071=Ubiquitin-related domain, IPR001012=UBX domain, IPR006567=PUG domain, IPR018997=PUB domain" CG5469 16-Dec-15 2015_12 ENSDARG00000003087(ubxn6) WBGene00019163(ubxn-6) ENSXETG00000024158(ubxd1) ENSMUSG00000019578(Ubxn6) ENSG00000167671(UBXN6) DRSC06934 K 0.361206605 -0.200481122 0.512960516 -1.012811105 -1.61677704 -0.484780597 FBgn0265949 CR44736 http://flybase.net/reports/FBgn0265949.html non_protein_coding_gene CR44736 16-Dec-15 2015_12 FBgn0260120 2L2853 http://flybase.net/reports/FBgn0260120.html gene "0007430=terminal branching, open tracheal system, 0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "terminal tracheal cell,somatic clone,dorsal air sac primordium,embryonic/larval tracheal system" FBgn0035267 CG13921 http://flybase.net/reports/FBgn0035267.html protein_coding_gene CG13921 16-Dec-15 2015_12 viable FBgn0033244 CG8726 http://flybase.net/reports/FBgn0033244.html protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding, 0035091=phosphatidylinositol binding, 0003779=actin binding" 0006468=protein phosphorylation "IPR001683=Phox homologous domain, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR003124=WH2 domain" CG8726 16-Dec-15 2015_12 ENSDARG00000063195(pxk) ENSXETG00000008675(PXK) ENSMUSG00000033885(Pxk) ENSG00000168297(PXK) viable FBgn0004683 Ifm(2)11 Indirect flight muscle (2) 11 http://flybase.net/reports/FBgn0004683.html gene 16-Dec-15 2015_12 "flight defective,dominant" "wing,myofibril,A band" FBgn0038576 Arp5 Actin-related protein 5 http://flybase.net/reports/FBgn0038576.html protein_coding_gene 0043140=ATP-dependent 3'-5' DNA helicase activity "0006338=chromatin remodeling, 0006355=regulation of transcription, DNA-templated, 0006281=DNA repair" "0031011=Ino80 complex, 0005634=nucleus" "CG7940, dArp5" "IPR027664=Actin-related protein 5, IPR004000=Actin family" CG7940 16-Dec-15 2015_12 ENSDARG00000012995(actr5) YNL059C(ARP5) ENSXETG00000012141(ACTR5) ENSMUSG00000037761(Actr5) ENSG00000101442(ACTR5) viable FBgn0040309 Jafrac1 thioredoxin peroxidase 1 http://flybase.net/reports/FBgn0040309.html FBgn0030472 protein_coding_gene "0008379=thioredoxin peroxidase activity, 0016209=antioxidant activity, 0004602=glutathione peroxidase activity, 0004601=peroxidase activity" "0008340=determination of adult lifespan, 0007281=germ cell development, 0006974=cellular response to DNA damage stimulus, 0042594=response to starvation, 0055114=oxidation-reduction process, 0042744=hydrogen peroxide catabolic process, 0007155=cell adhesion, 0045454=cell redox homeostasis, 0006979=response to oxidative stress, 0008354=germ cell migration" "0005875=microtubule associated complex, 0005829=cytosol" "PRDX1_DROME, jafrac1, Peroxiredoxin 1, Peroxiredoxin I, Dpx-4783, Jafrac, cTPx, jf1, Peroxiredoxin 4783, peroxidase, Prx, dPrx I, SSP5111, Thioredoxin peroxidase 1, DmTPx-1, peroxiredoxin, DPx4783, DPx-4783, T20, Prx4783, CG1633, 1633, thioredoxin peroxidase" "IPR024706=Peroxiredoxin, AhpC-type, IPR019479=Peroxiredoxin, C-terminal, IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336=Thioredoxin-like fold" CG1633 16-Dec-15 2015_12 "ENSDARG00000025350(prdx2),ENSDARG00000058734(zgc:110343)" "YML028W(TSA1),YDR453C(TSA2)" "ENSXETG00000004763(prdx2),ENSXETG00000003501(prdx1)" "ENSG00000167815(PRDX2),ENSG00000117450(PRDX1)" "cell migration defective,cell adhesion defective,oxidative stress response defective,starvation stress response defective,long lived,RU486 conditional,short lived,conditional" "germline cell,maternal effect" FBgn0061153 l(2)I46 lethal (2) I46 http://flybase.net/reports/FBgn0061153.html gene "I46, M237" 16-Dec-15 2015_12 "lethal,recessive" FBgn0037765 CG9458 http://flybase.net/reports/FBgn0037765.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane CT26802 IPR002076=ELO family CG9458 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" DRSC16495 I 0.66562253 1.785600847 0.526945437 -0.565277997 0.344965777 -0.250933127 FBgn0026262 bip2 bip2 http://flybase.net/reports/FBgn0026262.html protein_coding_gene "0003682=chromatin binding, 0002039=p53 binding, 0031208=POZ domain binding, 0008134=transcription factor binding, 0008270=zinc ion binding, 0005515=protein binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005669=transcription factor TFIID complex" "TAF3, CG2009, TAFII155, Bric-a-brac interacting protein 2, BIP2, TFIID, i31, TATA binding protein associated factor 3, i163, Bip2, dTAF[[II]]155, dBIP2, dTAFII3, bric-a-brac interacting protein 2, DmTAF3, TAF[[II]]155, Bric a brac Interacting Protein 2, TAF155, bip-II, dmTAF3" "IPR001965=Zinc finger, PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR006565=Bromodomain associated domain, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR019787=Zinc finger, PHD-finger" CG2009 16-Dec-15 2015_12 ENSDARG00000045513(taf3) ENSXETG00000001869(TAF3) ENSMUSG00000025782(Taf3) ENSG00000165632(TAF3) "lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable" DRSC17170 E -1.459721975 1.369222901 -1.563311271 0.625598761 1.014788422 1.085034966 FBgn0027991 l(3)S126801 lethal (3) S126801 http://flybase.net/reports/FBgn0027991.html gene 1268/01 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069119 ms(3)Z4934 ms(3)Z4934 http://flybase.net/reports/FBgn0069119.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile "onion stage spermatid,Nebenkern derivative,onion stage spermatid & nucleus" FBgn0265649 CR44456 http://flybase.net/reports/FBgn0265649.html non_protein_coding_gene CR44456 16-Dec-15 2015_12 FBgn0026253 ddbt deadbeat http://flybase.net/reports/FBgn0026253.html gene 16-Dec-15 2015_12 FBgn0267880 CR46168 http://flybase.net/reports/FBgn0267880.html pseudogene_attribute CG12717-related CR46168 16-Dec-15 2015_12 FBgn0023036 l(2)46Eg lethal (2) 46Eg http://flybase.net/reports/FBgn0023036.html gene "Complementation group W, W" 16-Dec-15 2015_12 "lethal,semidominant" embryonic/larval digestive system FBgn0038065 Snx3 Sorting nexin 3 http://flybase.net/reports/FBgn0038065.html protein_coding_gene 0032266=phosphatidylinositol-3-phosphate binding "0061355=Wnt protein secretion, 0035220=wing disc development, 0061359=regulation of Wnt signaling pathway by Wnt protein secretion, 0050821=protein stabilization, 0090263=positive regulation of canonical Wnt signaling pathway, 0006886=intracellular protein transport, 0006909=phagocytosis, 0061357=positive regulation of Wnt protein secretion, 0060070=canonical Wnt signaling pathway" "0005769=early endosome, 0030904=retromer complex" "snx3, lincRNA.S6645, CG6359, DmSNX3, sorting nexin 3, Dsnx3" IPR001683=Phox homologous domain CG6359 16-Dec-15 2015_12 "ENSDARG00000019060(snx12),ENSDARG00000008678(snx3)" YOR357C(SNX3) WBGene00006503(snx-3) "ENSXETG00000020904(snx12),ENSXETG00000024393(snx3)" "ENSMUSG00000046032(Snx12),ENSMUSG00000019804(Snx3)" "ENSG00000147164(SNX12),ENSG00000112335(SNX3)" "viable,fertile,partially lethal - majority die" "wing margin,wing margin bristle,somatic clone,wing" FBgn0010415 Sdc Syndecan http://flybase.net/reports/FBgn0010415.html FBgn0010667 protein_coding_gene 0004888=transmembrane signaling receptor activity "0044246=regulation of multicellular organismal metabolic process, 0050908=detection of light stimulus involved in visual perception, 0008045=motor neuron axon guidance, 2000637=positive regulation of gene silencing by miRNA, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0097009=energy homeostasis, 0021782=glial cell development, 0007427=epithelial cell migration, open tracheal system, 0007411=axon guidance" "0005576=extracellular region, 0098595=perivitelline space, 0045202=synapse, 0005925=focal adhesion, 0031594=neuromuscular junction, 0005886=plasma membrane" "dSdc, l(2)10608, Syn, dSyndecan, Dsyndecan, sdc, CT27296, CG10497, syndecan, Dsyn, syn, syd, Syd" "IPR031198=Syndecan, invertebrate, IPR001050=Syndecan, IPR003585=Neurexin/syndecan/glycophorin C, IPR030479=Syndecan, conserved site, IPR027789=Syndecan/Neurexin domain" CG10497 16-Dec-15 2015_12 WBGene00004749(sdn-1) "ENSXETG00000007104(SDC3),ENSXETG00000008902(SDC1)" "ENSMUSG00000025743(Sdc3),ENSMUSG00000020592(Sdc1)" ENSG00000169439(SDC2) embryonic stage | 7-15 hr " embryonic stage | 13-16 hr , embryonic stage | stage 16 " " ventral midline

, embryonic/larval midgut

, peripheral nervous system

, embryonic/larval hindgut

, posterior commissure

, lymph gland

, longitudinal connective

, embryonic/larval pharynx

, anterior commissure

" "viable,fertile,neuroanatomy defective,neurophysiology defective,lethal,recessive,immune response defective,size defective,female limited,female semi-fertile,short lived,hypoactive,male limited,sleep defective,starvation stress response defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live" "dorsal branch,dorsal branch | third instar larval stage,synapse,embryonic/larval salivary gland,eye photoreceptor cell & axon,lamina plexus,medulla,presumptive embryonic/larval central nervous system,NMJ bouton,anterior fascicle & axon | ectopic,embryonic somatic muscle,ventral,lateral transverse muscle,muscle fiber,fascicle,ectopic,abdominal segmental nerve,NMJ bouton | larval stage,adult ganglionic branch,terminal tracheal cell,tracheal fusion cell" DRSC04654 K 0.011152823 0.478141259 -0.271455981 0.079588875 0.257226323 2.798436584 FBgn0022002 l(2)k09314b lethal (2) k09314b http://flybase.net/reports/FBgn0022002.html gene l(2)k09314 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0060644 l(3)S084014b lethal (3) S084014b http://flybase.net/reports/FBgn0060644.html gene 0840/14 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0062597 Mod(var)1515 Mod(var)1515 http://flybase.net/reports/FBgn0062597.html gene 0006342=chromatin silencing 1515 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0004942 AcpA Accessory gland protein A http://flybase.net/reports/FBgn0004942.html gene 16-Dec-15 2015_12 FBgn0036704 CG6497 http://flybase.net/reports/FBgn0036704.html protein_coding_gene CG6497 16-Dec-15 2015_12 viable DRSC21469 IK 1.515529586 0.115235374 0.027906937 -0.275473706 1.564217441 0.234179804 FBgn0266643 CR45150 http://flybase.net/reports/FBgn0266643.html non_protein_coding_gene CR45150 16-Dec-15 2015_12 FBgn0060508 l(3)S104416b lethal (3) S104416b http://flybase.net/reports/FBgn0060508.html gene 1044/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0085629 CG41348 http://flybase.net/reports/FBgn0085629.html FBan0041348 protein_coding_gene 16-Dec-15 2015_12 FBgn0015516 lup-3 loop unfolding protein 3 http://flybase.net/reports/FBgn0015516.html gene "0007283=spermatogenesis, 0051276=chromosome organization" "ms(2)HB108, male sterile (2) HB108" 16-Dec-15 2015_12 male sterile "Y chromosome loop,spermatozoon" FBgn0267882 CR46170 http://flybase.net/reports/FBgn0267882.html pseudogene_attribute CG12717-related CR46170 16-Dec-15 2015_12 FBgn0065895 l(2)SH0212 lethal (2) SH0212 http://flybase.net/reports/FBgn0065895.html gene l(2)SH2 0212 16-Dec-15 2015_12 "lethal,recessive" FBgn0001165 gvl grooveless http://flybase.net/reports/FBgn0001165.html gene 16-Dec-15 2015_12 "viable,fertile,visible" scutellum FBgn0035206 CG9186 http://flybase.net/reports/FBgn0035206.html protein_coding_gene "0034389=lipid particle organization, 0030730=sequestering of triglyceride" "0005783=endoplasmic reticulum, 0005811=lipid particle, 0012505=endomembrane system" "IPR019363=Lipid droplet-associated hydrolase, IPR029058=Alpha/Beta hydrolase fold" CG9186 16-Dec-15 2015_12 YPR147C() "WBGene00008693(F11C1.4),WBGene00009140(F26A3.1)" ENSXETG00000008907(C2orf43) ENSMUSG00000037669(1110057K04Rik) ENSG00000118961(C2orf43) viable "lipid particleSgs3.PD,embryonic/larval salivary gland | third instar larval stage,lipid particlefat,lipid particletub.PU" FBgn0011983 tRNA:S7:12Eg transfer RNA:ser7:12Eg http://flybase.net/reports/FBgn0011983.html "FBgn0003830, FBgn0011968, FBgn0011979, FBgn0052609, FBgn0060069" tRNA_gene "0033405=UCU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[[7]][Ser], tRNA ser7, tRNA:ser, tRNA[Ser][[7]], 777-2, tRNA:S7, transfer RNA:ser7, tRNA:ser7, chrX.trna20-SerAGA, tRNA:S, CR32609, tRNA:S:AGA:AE002593-c, tRNA[[Ser]], AE002593.trna11-SerAGA, tRNA[Ser], transfer RNA:ser, tRNA:ser7:12Eg, Ser-tRNA-7" CR32609 16-Dec-15 2015_12 FBgn0030313 CG11697 http://flybase.net/reports/FBgn0030313.html FBgn0066828 protein_coding_gene "anon-WO03040301.203, a" IPR004345=TB2/DP1/HVA22-related protein CG11697 16-Dec-15 2015_12 "ENSXETG00000007690(REEP3),ENSXETG00000010537(BC090588.1),ENSXETG00000017972(REEP1)" DRSC19418 K -0.325502029 0.804681252 0.237684872 0.259733164 -0.584223611 -1.550965857 FBgn0266674 Sec15 Sec15 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266674.html "FBgn0266614, FBgn0038856" protein_coding_gene 0017137=Rab GTPase binding "0016192=vesicle-mediated transport, 0072659=protein localization to plasma membrane, 0022416=chaeta development, 0016081=synaptic vesicle docking, 0042331=phototaxis, 0016080=synaptic vesicle targeting, 0007298=border follicle cell migration, 0090522=vesicle tethering involved in exocytosis, 0007269=neurotransmitter secretion, 0007411=axon guidance, 0006904=vesicle docking involved in exocytosis, 0032456=endocytic recycling" "0000145=exocyst, 0055037=recycling endosome, 0005768=endosome, 0031410=cytoplasmic vesicle, 0043679=axon terminus" "CG7034, Sec15p, dsec15, 3R41, sec15" IPR007225=Exocyst complex subunit Sec15-like CG7034 16-Dec-15 2015_12 ENSDARG00000020521(exoc6) YGL233W(SEC15) WBGene00016188(sec-15) "ENSXETG00000018180(EXOC6),ENSXETG00000021542(EXOC6B)" "ENSMUSG00000053799(Exoc6),ENSMUSG00000033769(Exoc6b)" "ENSG00000144036(EXOC6B),ENSG00000138190(EXOC6)" FBgn0267042 CG45486 http://flybase.net/reports/FBgn0267042.html protein_coding_gene CG45486 16-Dec-15 2015_12 FBgn0027490 D12 D12 http://flybase.net/reports/FBgn0027490.html protein_coding_gene 0004402=histone acetyltransferase activity "0006338=chromatin remodeling, 0006355=regulation of transcription, DNA-templated, 0016573=histone acetylation" "0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0005700=polytene chromosome" "CG13400, Yeats2" IPR005033=YEATS CG13400 16-Dec-15 2015_12 ENSMUSG00000041215(Yeats2) ENSG00000163872(YEATS2) viable FBgn0052336 CG32336 http://flybase.net/reports/FBgn0052336.html protein_coding_gene 16-Dec-15 2015_12 FBgn0052667 ssp7 short spindle 7 http://flybase.net/reports/FBgn0052667.html protein_coding_gene "0032504=multicellular organism reproduction, 0090307=mitotic spindle assembly" 0005615=extracellular space "Ssp7, CG32667, CG32677" "IPR001007=VWFC domain, IPR029277=Single domain Von Willebrand factor type C domain" CG32667 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0024870 l(2)k13215 lethal (2) k13215 http://flybase.net/reports/FBgn0024870.html gene 16-Dec-15 2015_12 "viable,lethal" FBgn0263760 CG43677 http://flybase.net/reports/FBgn0263760.html protein_coding_gene CG43677 16-Dec-15 2015_12 FBgn0265545 CR44395 http://flybase.net/reports/FBgn0265545.html non_protein_coding_gene CR44395 16-Dec-15 2015_12 FBgn0003596 Su(var)3-5 Suppressor of variegation 3-5 http://flybase.net/reports/FBgn0003596.html gene Su-var5 16-Dec-15 2015_12 "lethal,partially,recessive,female sterile,male sterile,chemical sensitive,suppressor of variegation,dominant" FBgn0014995 osk::Dvir\osk osk::Dvir\osk http://flybase.net/reports/FBgn0014995.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,maternal effect,dominant" "embryo,maternal effect" FBgn0037262 MED31 Mediator complex subunit 31 http://flybase.net/reports/FBgn0037262.html FBgn0064932 protein_coding_gene "0003713=transcription coactivator activity, 0001104=RNA polymerase II transcription cofactor activity" "0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0007406=negative regulation of neuroblast proliferation, 0008595=anterior/posterior axis specification, embryo" "0005634=nucleus, 0016592=mediator complex" "Mediator, dSOH1, BcDNA:GM28912, p36, med31, dTRAP18, Trap18, Med31, CG1057" "IPR008831=Mediator complex, subunit Med31" CG1057 16-Dec-15 2015_12 ENSDARG00000008020(med31) WBGene00007026(mdt-31) ENSXETG00000017618(med31) ENSMUSG00000020801(Med31) ENSG00000108590(MED31) "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,cell growth defective,lethal - all die before end of pupal stage,some die during pupal stage" "mitotic domain,non-rescuable maternal effect,pole cell,tergite,maternal effect,adult epidermis,sternite,haltere" FBgn0085727 CG42200 http://flybase.net/reports/FBgn0085727.html FBan0042200 protein_coding_gene 16-Dec-15 2015_12 FBgn0051300 CG31300 http://flybase.net/reports/FBgn0051300.html FBgn0039314 protein_coding_gene CG13657 "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG31300 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" viable FBgn0027786 Mtch Mitochondrial carrier homolog 1 http://flybase.net/reports/FBgn0027786.html protein_coding_gene 0022857=transmembrane transporter activity 0005739=mitochondrion CG6851 "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG6851 16-Dec-15 2015_12 ENSDARG00000019732(mtch2) WBGene00018395(F43E2.7) ENSXETG00000019935(mtch2) "ENSMUSG00000024012(Mtch1),ENSMUSG00000027282(Mtch2)" "ENSG00000109919(MTCH2),ENSG00000137409(MTCH1)" "neuroanatomy defective,viable,visible" "mushroom body & axon7B,Kenyon cell,adult mushroom body,mushroom body & axonc739,trichogen cell" FBgn0050147 Hil Hillarin http://flybase.net/reports/FBgn0050147.html "FBgn0034525, FBgn0034526" protein_coding_gene 0008270=zinc ion binding "D-hillarin, D-Hillarin, CG10439, CG30147, D-hil, CG13435" "IPR001781=Zinc finger, LIM-type" CG30147 16-Dec-15 2015_12 WBGene00003089(ltd-1) ENSXETG00000004350(KY) ENSMUSG00000035606(Ky) ENSG00000174611(KY) "viable,visible" trichogen cell FBgn0004066 Prosë±4 Proteasome ë±4 subunit http://flybase.net/reports/FBgn0004066.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006511=ubiquitin-dependent protein catabolic process" "0005839=proteasome core complex, 0005875=microtubule associated complex, 0000502=proteasome complex, 0019773=proteasome core complex, alpha-subunit complex" "alpha-subunit of 20S proteasome, alpha-4, 28.1Pros, Prosalpha4, pros28.1, Pros28.1, PROS-28.1, unnamed, alpha4, Pros28, PROS-Dm28.1, a4, CG3422, Proteasome 28kD subunit 1, 20S proteasome, alpha4_dm, 3422, Alpha-4, PSA4_DROME, 20s proteasome, PROSA-28.1, Pros-Dm28.1" "IPR023332=Proteasome A-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR001353=Proteasome, subunit alpha/beta" CG3422 16-Dec-15 2015_12 ENSDARG00000010965(psma8) YOL038W(PRE6) WBGene00003925(pas-4) ENSXETG00000001998(psma7) "ENSMUSG00000036743(Psma8),ENSMUSG00000027566(Psma7)" "ENSG00000154611(PSMA8),ENSG00000101182(PSMA7)" viable FBgn0033615 CG7741 http://flybase.net/reports/FBgn0033615.html protein_coding_gene "0003824=catalytic activity, 0008419=RNA lariat debranching enzyme activity" "IPR029052=Metallo-dependent phosphatase-like, IPR011146=HIT-like domain, IPR006767=Cwf19-like protein, C-terminal domain-2, IPR006768=Cwf19-like, C-terminal domain-1" CG7741 16-Dec-15 2015_12 ENSDARG00000002128(cwf19l1) YGR093W() WBGene00017534(F17A9.2) ENSXETG00000003719(CWF19L1) ENSMUSG00000025200(Cwf19l1) ENSG00000095485(CWF19L1) viable FBgn0262112 sro shroud http://flybase.net/reports/FBgn0262112.html "FBgn0003506, FBgn0262014, FBgn0039695" protein_coding_gene 0003858=3-hydroxybutyrate dehydrogenase activity 0006697=ecdysone biosynthetic process CG12068 "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase, IPR020904=Short-chain dehydrogenase/reductase, conserved site" CG12068 16-Dec-15 2015_12 FBgn0001355 l(1)1EFd lethal (1) 1EFd http://flybase.net/reports/FBgn0001355.html gene l(1)BA4 16-Dec-15 2015_12 lethal FBgn0082678 E(ftz)4758 E(ftz)4758 http://flybase.net/reports/FBgn0082678.html gene 4758 16-Dec-15 2015_12 FBgn0086223 Chifoumi Chifoumi http://flybase.net/reports/FBgn0086223.html gene 0046426=negative regulation of JAK-STAT cascade 16-Dec-15 2015_12 FBgn0022770 Peritrophin-A Peritrophin A http://flybase.net/reports/FBgn0022770.html protein_coding_gene "0016490=structural constituent of peritrophic membrane, 0008061=chitin binding" "0032504=multicellular organism reproduction, 0006030=chitin metabolic process" 0005615=extracellular space "CG17058, PeriA, peritrophin A, CG31559, obst-D, Dm-peritrophin-A" IPR002557=Chitin binding domain CG17058 16-Dec-15 2015_12 viable FBgn0004517 l(4)102ABd lethal (4) 102ABd http://flybase.net/reports/FBgn0004517.html gene "l(4)Abd, l(4)32, l(4)27, l(4)30, l(4)28, l(4)1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0014907 anon-4Fa anon-4Fa http://flybase.net/reports/FBgn0014907.html gene 16-Dec-15 2015_12 FBgn0050035 Tret1-1 Trehalose transporter 1-1 http://flybase.net/reports/FBgn0050035.html "FBgn0033642, FBgn0033643" protein_coding_gene 0005355=glucose transmembrane transporter activity "0008643=carbohydrate transport, 0015771=trehalose transport, 0055085=transmembrane transport" "0016020=membrane, 0016021=integral component of membrane" "Tre T1, trehalose transporter 1, DmTret1-1, CG7801, CG30035, CG7797" "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like, IPR003663=Sugar/inositol transporter" CG30035 16-Dec-15 2015_12 "ENSDARG00000020344(slc2a8),ENSDARG00000058731(LOC560602)" YDR387C() "WBGene00010811(hmit-1.3),WBGene00013073(hmit-1.1),WBGene00013074(hmit-1.2)" "ENSXETG00000019602(SLC2A8),ENSXETG00000006884(SLC2A6)" "ENSMUSG00000026791(Slc2a8),ENSMUSG00000036067(Slc2a6)" "ENSG00000136856(SLC2A8),ENSG00000160326(SLC2A6)" viable FBgn0005494 l(1)ts5569 lethal (1) ts5569 http://flybase.net/reports/FBgn0005494.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0040628 CG18672 http://flybase.net/reports/FBgn0040628.html protein_coding_gene "0008270=zinc ion binding, 0004089=carbonate dehydratase activity" 0006730=one-carbon metabolic process "IPR023561=Carbonic anhydrase, alpha-class, IPR001148=Alpha carbonic anhydrase, IPR018338=Carbonic anhydrase, alpha-class, conserved site" CG18672 16-Dec-15 2015_12 WBGene00000283(cah-5) "ENSMUSG00000079715,ENSMUSG00000028463(Car9)" viable DRSC15371 K -0.082413136 0.45188094 -0.014645669 0.451437021 -1.569937634 0.151019461 FBgn0053643 CG33643 http://flybase.net/reports/FBgn0053643.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33643 16-Dec-15 2015_12 viable FBgn0266627 CR45134 http://flybase.net/reports/FBgn0266627.html non_protein_coding_gene CR45134 16-Dec-15 2015_12 FBgn0065776 l(2)SH0453 lethal (2) SH0453 http://flybase.net/reports/FBgn0065776.html gene l(2)SH2 0453 16-Dec-15 2015_12 "lethal,recessive" FBgn0014273 l(2)k11512 lethal (2) k11512 http://flybase.net/reports/FBgn0014273.html gene 0007446=imaginal disc growth l(2)115/12 16-Dec-15 2015_12 "hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc,embryonic/larval brain" FBgn0262330 mir-193 mir-193 stem loop http://flybase.net/reports/FBgn0262330.html miRNA_gene "CR43037, dme-mir-193, miR-193" CR43037 16-Dec-15 2015_12 "visible,partially lethal - majority die,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein L5,wing vein" FBgn0004784 inaC inactivation no afterpotential C http://flybase.net/reports/FBgn0004784.html "FBgn0001262, FBgn0003092" protein_coding_gene "0004698=calcium-dependent protein kinase C activity, 0004674=protein serine/threonine kinase activity, 0004697=protein kinase C activity, 0019992=diacylglycerol binding, 0005524=ATP binding, 0005515=protein binding, 0008270=zinc ion binding" "0035556=intracellular signal transduction, 0016062=adaptation of rhodopsin mediated signaling, 0006909=phagocytosis, 0050962=detection of light stimulus involved in sensory perception, 0019722=calcium-mediated signaling, 0030845=phospholipase C-inhibiting G-protein coupled receptor signaling pathway, 0016477=cell migration, 2000370=positive regulation of clathrin-mediated endocytosis, 0007602=phototransduction, 0008585=female gonad development, 0006468=protein phosphorylation, 0016059=deactivation of rhodopsin mediated signaling, 0045471=response to ethanol, 0009416=response to light stimulus" "0016027=inaD signaling complex, 0005768=endosome, 0016028=rhabdomere, 0005886=plasma membrane" "PKC, Pkc2, pkc-2, eye-specific PKC, unnamed, ePKC, PK-C, Dpkc2, eye-PKC, INAC, InaC, Protein-kinase-2, CG6518, eye PKC, protein kinase C, PKC-eye, PKC2, Inactivation no afterpotential C, eye-protein-kinase C, PKCi, protein-kinase-C, eyePKC, dPKC53E(ey), dPKC53E, Protein kinase-c2, PKC 53E" "IPR017441=Protein kinase, ATP binding site, IPR014375=Protein kinase C, alpha/beta/gamma types, IPR000719=Protein kinase domain, IPR020454=Diacylglycerol/phorbol-ester binding, IPR017892=Protein kinase, C-terminal, IPR008271=Serine/threonine-protein kinase, active site, IPR000008=C2 domain, IPR011009=Protein kinase-like domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal" CG6518 16-Dec-15 2015_12 YBL105C(PKC1) " adult stage , pupal stage | late " " ocellus

, eye

, head

, photoreceptor cell

" adult stage " eye

, ocellus

, rhabdomere

" "viable,fertile,wild-type,visual behavior defective,recessive,neurophysiology defective,semidominant,behavior defective,chemical resistant" "photoreceptor cell,photoreceptor,eye,retina,ovary,germarium,egg chamber,ovarian sheath,gustatory receptor neuron" FBgn0265304 CR44277 http://flybase.net/reports/FBgn0265304.html non_protein_coding_gene CR44277 16-Dec-15 2015_12 FBgn0262536 CG43090 http://flybase.net/reports/FBgn0262536.html protein_coding_gene CG43090 16-Dec-15 2015_12 FBgn0061119 l(3)S005115 lethal (3) S005115 http://flybase.net/reports/FBgn0061119.html gene 0051/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0046999 CG6429 http://flybase.net/reports/FBgn0046999.html FBgn0034164 protein_coding_gene 0003796=lysozyme activity BcDNA:RH62928 "IPR008597=Destabilase, IPR023346=Lysozyme-like domain" CG6429 16-Dec-15 2015_12 "WBGene00017691(ilys-5),WBGene00016670(ilys-3),WBGene00016669(ilys-2),WBGene00016668(ilys-1),WBGene00016958(ilys-4)" viable DRSC06986 I -0.326470116 2.424769143 0.239269972 0.291995136 -0.041039761 0.386532504 FBgn0030349 CG10353 http://flybase.net/reports/FBgn0030349.html protein_coding_gene 0005229=intracellular calcium activated chloride channel activity 0006821=chloride transport 0070062=extracellular exosome IPR007632=Anoctamin CG10353 16-Dec-15 2015_12 WBGene00010138(F56A8.1) viable FBgn0086299 lackluster lackluster http://flybase.net/reports/FBgn0086299.html gene lack 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0033863 CG13337 http://flybase.net/reports/FBgn0033863.html protein_coding_gene CG13337 16-Dec-15 2015_12 viable FBgn0266007 CR44780 http://flybase.net/reports/FBgn0266007.html non_protein_coding_gene CR44780 16-Dec-15 2015_12 FBgn0259304 EP-112 http://flybase.net/reports/FBgn0259304.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta" FBgn0060641 l(3)S084204b lethal (3) S084204b http://flybase.net/reports/FBgn0060641.html gene 0842/04 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0026346 Su(dpp)39CDE Su(dpp)39CDE http://flybase.net/reports/FBgn0026346.html gene 0008101=decapentaplegic signaling pathway 16-Dec-15 2015_12 "viable,fertile" FBgn0263482 snoRNA:lola-c http://flybase.net/reports/FBgn0263482.html snoRNA_gene CR43597 16-Dec-15 2015_12 FBgn0039316 CG11893 http://flybase.net/reports/FBgn0039316.html protein_coding_gene "0022416=chaeta development, 0035220=wing disc development" "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG11893 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" "viable,fertile,planar polarity defective" FBgn0033954 CG12860 http://flybase.net/reports/FBgn0033954.html FBgn0044552 protein_coding_gene "anon-WO0140519.75, bs33f06.y1" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG12860 16-Dec-15 2015_12 viable FBgn0030752 CG9947 http://flybase.net/reports/FBgn0030752.html protein_coding_gene 0016020=membrane IPR005045=CDC50/LEM3 family CG9947 16-Dec-15 2015_12 "ENSDARG00000030236(tmem30a),ENSDARG00000043555(zgc:77655)" "YCR094W(CDC50),YNR048W(),YNL323W(LEM3)" WBGene00019946(R08C7.2) ENSXETG00000003607(BC061349.1) "ENSMUSG00000032328(Tmem30a),ENSMUSG00000034435(Tmem30b)" ENSG00000112697(TMEM30A) "partially lethal - majority die,some die during pupal stage" FBgn0266508 s-436 http://flybase.net/reports/FBgn0266508.html gene 16-Dec-15 2015_12 FBgn0037620 ranshi ranshi http://flybase.net/reports/FBgn0037620.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "0030706=germarium-derived oocyte differentiation, 0009994=oocyte differentiation" 0035145=exon-exon junction complex "ranshi, CG9793" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG9793 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "viable,fertile,male fertile,female sterile" "karyosome,germarium region 3,synaptonemal complex" FBgn0033605 CG9067 http://flybase.net/reports/FBgn0033605.html protein_coding_gene 0006888=ER to Golgi vesicle-mediated transport 0005622=intracellular "TRAPPC2L, Tca17" "IPR006722=Trafficking protein particle complex subunit 2, IPR011012=Longin-like domain" CG9067 16-Dec-15 2015_12 ENSDARG00000035799(trappc2l) WBGene00044604(T10F2.5) ENSXETG00000027081(TRAPPC2L) ENSMUSG00000015013(Trappc2l) ENSG00000167515(TRAPPC2L) "viable,fertile" FBgn0267100 CR45540 http://flybase.net/reports/FBgn0267100.html non_protein_coding_gene CR45540 16-Dec-15 2015_12 FBgn0262889 CG43244 http://flybase.net/reports/FBgn0262889.html protein_coding_gene CG43244 16-Dec-15 2015_12 FBgn0083049 snoRNA:ë¬18S-1377c snoRNA:ë¬18S-1377c http://flybase.net/reports/FBgn0083049.html snoRNA_gene "Psi18S-1377c, CR34627, psi18S-1377c, chr3R:26033056..26033194" CR34627 16-Dec-15 2015_12 FBgn0038959 CG13856 http://flybase.net/reports/FBgn0038959.html protein_coding_gene CG13856 16-Dec-15 2015_12 viable FBgn0013450 fs(2)ry6 fs(2)ry6 http://flybase.net/reports/FBgn0013450.html gene "fs(2)6, unnamed" 16-Dec-15 2015_12 "male fertile,poor,female sterile" FBgn0037378 CG2046 http://flybase.net/reports/FBgn0037378.html protein_coding_gene 0000502=proteasome complex CG2046 16-Dec-15 2015_12 "viable,fertile" FBgn0083292 E(smoDN)203 Enhancer of smoDN 203 http://flybase.net/reports/FBgn0083292.html gene 16-Dec-15 2015_12 FBgn0013243 E(var)236 E(var)236 http://flybase.net/reports/FBgn0013243.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0266232 CR44927 http://flybase.net/reports/FBgn0266232.html non_protein_coding_gene lincRNA.686 CR44927 16-Dec-15 2015_12 FBgn0002272 l(3)69Bd lethal (3) 69Bd http://flybase.net/reports/FBgn0002272.html gene "l(3)rsg34, rsg34, rose-gespleten region interval 34" 16-Dec-15 2015_12 lethal FBgn0065186 l(2)SH2348 lethal (2) SH2348 http://flybase.net/reports/FBgn0065186.html gene l(2)SH2 2348 16-Dec-15 2015_12 "lethal,recessive" FBgn0036833 CG3819 http://flybase.net/reports/FBgn0036833.html protein_coding_gene "0016787=hydrolase activity, 0003676=nucleic acid binding, 0046872=metal ion binding" CT12789 "IPR020821=Extracellular Endonuclease, subunit A, IPR001604=DNA/RNA non-specific endonuclease" CG3819 16-Dec-15 2015_12 "ENSDARG00000063613,ENSDARG00000071216,ENSDARG00000071224(si:ch211-133n4.4),ENSDARG00000071223(zgc:158445),ENSDARG00000063044,ENSDARG00000068523,ENSDARG00000069190(zgc:172339),ENSDARG00000068065,ENSDARG00000061611(LOC556323),ENSDARG00000060913,ENSDARG00000061822,ENSDARG00000070242(zgc:171534)" "viable,planar polarity defective" FBgn0022715 19w 19w http://flybase.net/reports/FBgn0022715.html gene 16-Dec-15 2015_12 mitotic cell cycle defective larval brain & nuclear chromosome FBgn0023407 B4 B4 http://flybase.net/reports/FBgn0023407.html FBgn0040974 protein_coding_gene "0007444=imaginal disc development, 0007623=circadian rhythm" 0005886=plasma membrane "Suppressor of signaling by insulin, CG9260, B4/Susi, CG9239, n(2)05337, BG:DS07660.4, Susi" IPR025946=CABIT domain CG9239 16-Dec-15 2015_12 " embryonic stage , larval stage | third instar " " sensory mother cell

, neuroblast

, imaginal disc | ubiquitous

,

ubiquitous " "viable,fertile,visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,large body,decreased cell number,somatic clone,decreased cell size,cell non-autonomous,small body" "imaginal disc,wing,wing vein,eye,ommatidium,eye photoreceptor cell,cell non-autonomous,somatic clone,trichogen cell" DRSC01868 I -0.349250766 6.010795913 0.31803317 0.521555461 -0.979776385 -1.351511492 FBgn0002901 mus304 mutagen-sensitive 304 http://flybase.net/reports/FBgn0002901.html "FBgn0036776, FBgn0044544" protein_coding_gene 0004003=ATP-dependent DNA helicase activity "0007143=female meiotic division, 0006281=DNA repair, 0016321=female meiosis chromosome segregation, 0000723=telomere maintenance, 0009314=response to radiation, 0007444=imaginal disc development, 0000077=DNA damage checkpoint, 0006974=cellular response to DNA damage stimulus, 0033314=mitotic DNA replication checkpoint, 0007093=mitotic cell cycle checkpoint, 0007095=mitotic G2 DNA damage checkpoint, 0007131=reciprocal meiotic recombination, 0007348=regulation of syncytial blastoderm mitotic cell cycle" 0005737=cytoplasm "mutagen sensitive 304, mus(3)304, ATRIP, atrip, mus-304, ATR-interacting protein, Mus304, anon-WO0140519.82, CG7347" CG7347 16-Dec-15 2015_12 ENSXETG00000020928(ATRIP) ENSMUSG00000025646(Atrip) ENSG00000164053(ATRIP) "viable,visible,recessive,chemical sensitive,radiation sensitive,meiotic cell cycle defective,mitotic cell cycle defective,increased cell death,DNA repair defective,wild-type" "macrochaeta,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo,mitotic cell cycle,mitosis & nuclear chromosome,nucleus | embryonic stage,wing disc,mesothoracic tergum" FBgn0003057 CG10598 http://flybase.net/reports/FBgn0003057.html protein_coding_gene "GCR 17, GCR-11, GCR17, Pen15EF, pen15EF, anon-Pen15EF, GCR11" CG10598 16-Dec-15 2015_12 FBgn0037690 Task7 TWIK-related acid-sensitive K+ channel 7 http://flybase.net/reports/FBgn0037690.html protein_coding_gene "0005267=potassium channel activity, 0046982=protein heterodimerization activity, 0005252=open rectifier potassium channel activity" 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "K2P-TASK7, CG9361, dTASK-7, Task7" "IPR013099=Potassium channel domain, IPR003280=Two pore domain potassium channel, IPR003092=Two pore domain potassium channel, TASK family" CG9361 16-Dec-15 2015_12 "ENSDARG00000043466(kcnk3),ENSDARG00000052898(LOC571330)" ENSXETG00000022828() "ENSMUSG00000049265(Kcnk3),ENSMUSG00000036760(Kcnk9),ENSMUSG00000035238(Kcnk15)" "ENSG00000169427(KCNK9),ENSG00000171303(KCNK3)" "viable,fertile" FBgn0001095 gcd giant cell defect http://flybase.net/reports/FBgn0001095.html gene 16-Dec-15 2015_12 FBgn0005269 l(3)SG89 lethal (3) SG89 http://flybase.net/reports/FBgn0005269.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0061492 loj logjam http://flybase.net/reports/FBgn0061492.html "FBgn0010829, FBgn0035680" protein_coding_gene 0005215=transporter activity "0006810=transport, 0048193=Golgi vesicle transport, 0048042=regulation of post-mating oviposition, 0000003=reproduction, 0018991=oviposition" "0016021=integral component of membrane, 0005801=cis-Golgi network, 0005793=endoplasmic reticulum-Golgi intermediate compartment" "l(3)04026, p24, LOJ, CG10733" "IPR009038=GOLD domain, IPR015720=TMP21-related" CG10733 16-Dec-15 2015_12 ENSG00000157315(TMED6) "viable,female sterile,recessive,lethal,partially lethal - majority die" FBgn0001977 CIAPIN1 CIAPIN1 ortholog http://flybase.net/reports/FBgn0001977.html "FBgn0015867, FBgn0027853, FBgn0032560" protein_coding_gene 0051536=iron-sulfur cluster binding "0030707=ovarian follicle cell development, 0043066=negative regulation of apoptotic process, 0016226=iron-sulfur cluster assembly" 0005737=cytoplasm "B, BG:DS00929.9, D-CIAPIN1, lethal (2) 35Bg, D1, lethal 26 in the black-reduced region, br26, transcription unit B, anon-35Ba, l(2)br26, l(2)35Bg, lethal group D1, CG4180" IPR007785=Anamorsin CG4180 16-Dec-15 2015_12 ENSDARG00000045733(ciapin1) ENSXETG00000013788(ciapin1) ENSMUSG00000031781(Ciapin1) "lethal,recessive,viable,female sterile,male sterile,mitotic cell cycle defective,increased cell death,lethal - all die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,partially lethal - majority die" "ovary,follicle cell" FBgn0043063 Tl::Toll-4 Tl::Toll-4 http://flybase.net/reports/FBgn0043063.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0262823 CG43194 http://flybase.net/reports/FBgn0262823.html protein_coding_gene CG43194 16-Dec-15 2015_12 FBgn0038009 CG17738 http://flybase.net/reports/FBgn0038009.html protein_coding_gene CG17738 16-Dec-15 2015_12 viable FBgn0022249 l(2)k01301 lethal (2) k01301 http://flybase.net/reports/FBgn0022249.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011945 tRNA:P:90Cb transfer RNA:pro:90Cb http://flybase.net/reports/FBgn0011945.html "FBgn0003819, FBgn0051571, FBgn0060114" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033423=CCA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:pro:90Cb, tRNA:P:TGG:AE002708-a, tRNA:Pro, CR31571, Pro, AE002708.trna11-ProTGG, chr3R.trna17-ProTGG" CR31571 16-Dec-15 2015_12 FBgn0032785 CG10026 http://flybase.net/reports/FBgn0032785.html protein_coding_gene "0016918=retinal binding, 0005215=transporter activity, 0008431=vitamin E binding" 0006810=transport 0005622=intracellular "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG10026 16-Dec-15 2015_12 "viable,fertile" FBgn0010135 mat(2)N maternal lethal (2) Notchlike http://flybase.net/reports/FBgn0010135.html gene "0001700=embryonic development via the syncytial blastoderm, 0007399=nervous system development" l(2)31Ei 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0001036 fs(3)G3 female sterile (3) G3 http://flybase.net/reports/FBgn0001036.html gene fs(3)3 16-Dec-15 2015_12 "female sterile,male fertile" egg chamber FBgn0028607 l(2)W18 lethal (2) W18 http://flybase.net/reports/FBgn0028607.html gene l(2R)W18 16-Dec-15 2015_12 "lethal,recessive" FBgn0015257 M1-52 M1-52 http://flybase.net/reports/FBgn0015257.html gene 16-Dec-15 2015_12 FBgn0039485 CG17189 http://flybase.net/reports/FBgn0039485.html protein_coding_gene 0005615=extracellular space cg17189 IPR010562=Haemolymph juvenile hormone binding CG17189 16-Dec-15 2015_12 FBgn0037108 CG11306 http://flybase.net/reports/FBgn0037108.html protein_coding_gene "0000026=alpha-1,2-mannosyltransferase activity" "0009058=biosynthetic process, 0022008=neurogenesis" "Alg11, dAlg11, putative alpha-1,2-mannosyltransferase activity" "IPR001296=Glycosyl transferase, family 1" CG11306 16-Dec-15 2015_12 ENSDARG00000031202(alg11) YNL048W(ALG11) WBGene00015162(B0361.8) ENSXETG00000020712(BC064222.1) ENSMUSG00000063362(Alg11) ENSG00000136112 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0039464 CG6330 http://flybase.net/reports/FBgn0039464.html protein_coding_gene 0004850=uridine phosphorylase activity "0009166=nucleotide catabolic process, 0042332=gravitaxis, 0009116=nucleoside metabolic process" 0005737=cytoplasm "IPR000845=Nucleoside phosphorylase domain, IPR010059=Uridine phosphorylase, eukaryotic, IPR018017=Nucleoside phosphorylase" CG6330 16-Dec-15 2015_12 "ENSDARG00000036833(upp2),ENSDARG00000040869(LOC100330564)" WBGene00022817(upp-1) "ENSXETG00000010379(upp2),ENSXETG00000015681(upp1)" "ENSMUSG00000026839(Upp2),ENSMUSG00000020407(Upp1)" "ENSG00000007001(UPP2),ENSG00000183696(UPP1)" "viable,fertile,female fertile,lethal,gravitaxis defective" FBgn0085688 CG41557 http://flybase.net/reports/FBgn0085688.html FBan0041557 protein_coding_gene 16-Dec-15 2015_12 FBgn0263657 CR43648 http://flybase.net/reports/FBgn0263657.html non_protein_coding_gene CR43648 16-Dec-15 2015_12 FBgn0067664 p80 p80 http://flybase.net/reports/FBgn0067664.html gene 16-Dec-15 2015_12 FBgn0264873 CR44064 http://flybase.net/reports/FBgn0264873.html non_protein_coding_gene CR44064 16-Dec-15 2015_12 FBgn0004008 Washed-eye Washed eye http://flybase.net/reports/FBgn0004008.html gene We 16-Dec-15 2015_12 "lethal,recessive,viable,fertile,eye color defective" eye FBgn0259992 CG42489 http://flybase.net/reports/FBgn0259992.html protein_coding_gene CG42489 16-Dec-15 2015_12 FBgn0040383 CG5254 http://flybase.net/reports/FBgn0040383.html FBgn0029533 protein_coding_gene "0005371=tricarboxylate secondary active transmembrane transporter activity, 0022857=transmembrane transporter activity" "0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0006839=mitochondrial transport" 0031966=mitochondrial membrane "EG:BACR19J1.2, CT16777" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG5254 16-Dec-15 2015_12 ENSDARG00000060564(slc25a21) "YOR222W(ODC2),YPL134C(ODC1)" WBGene00011226(R11.1) ENSXETG00000012316(SLC25A21) ENSMUSG00000035472(Slc25a21) ENSG00000183032(SLC25A21) pupal stage salivary gland

viable FBgn0067388 c625 c625 http://flybase.net/reports/FBgn0067388.html gene 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0011625 l(2)T56i26 lethal (2) T56i26 http://flybase.net/reports/FBgn0011625.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0038717 CG17751 http://flybase.net/reports/FBgn0038717.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG17751 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0011713 snowballs snowballs http://flybase.net/reports/FBgn0011713.html gene snb 16-Dec-15 2015_12 male sterile "spermatid,meiosis & nuclear chromosome" FBgn0015560 upo unipolar disorder http://flybase.net/reports/FBgn0015560.html FBgn0022149 gene "uni, l(2)k05916" 16-Dec-15 2015_12 "lethal,recessive" FBgn0037165 CG11437 http://flybase.net/reports/FBgn0037165.html protein_coding_gene 0008195=phosphatidate phosphatase activity "0016311=dephosphorylation, 0006644=phospholipid metabolic process" 0016020=membrane "LPP-like, WUN-like" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG11437 16-Dec-15 2015_12 viable DRSC11659 IE 2.020201057 -0.014805558 2.136391485 1.142964818 -0.394853713 0.553634584 FBgn0060567 l(3)S096511 lethal (3) S096511 http://flybase.net/reports/FBgn0060567.html gene 0965/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0028064 l(3)S092405 lethal (3) S092405 http://flybase.net/reports/FBgn0028064.html gene 0924/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0036221 CG11588 http://flybase.net/reports/FBgn0036221.html protein_coding_gene CG11588 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0032033 CG13392 http://flybase.net/reports/FBgn0032033.html protein_coding_gene "IPR009801=Protein of unknown function DUF1370, TMEM126" CG13392 16-Dec-15 2015_12 ENSDARG00000014506(tmem126a) FBgn0005722 l(1)TK131 lethal (1) TK131 http://flybase.net/reports/FBgn0005722.html gene l131 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0004027 wtw water wings http://flybase.net/reports/FBgn0004027.html gene "cleft, cleft end, clf" 16-Dec-15 2015_12 "visible,recessive,viable,male,reduced,male fertile,female fertile,female sterile" "eye,wing,male genitalia,adult abdomen,male,crossvein,female,posterior" FBgn0039728 CG7896 http://flybase.net/reports/FBgn0039728.html protein_coding_gene "tartan/capricious-like, CT23878" "IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal, IPR001611=Leucine-rich repeat" CG7896 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum FBgn0267512 5.8SrRNA:CR45852 5.8S ribosomal RNA:CR45852 http://flybase.net/reports/FBgn0267512.html rRNA_gene CR45852 CR45852 16-Dec-15 2015_12 FBgn0035727 CG10063 http://flybase.net/reports/FBgn0035727.html FBgn0063698 protein_coding_gene BcDNA:AT30027 CG10063 16-Dec-15 2015_12 "viable,fertile" DRSC09688 EK 0.551615388 0.239764117 0.158572023 1.543806654 1.760408554 0.496755182 FBgn0034062 CG8388 http://flybase.net/reports/FBgn0034062.html protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR017956=AT hook, DNA-binding motif, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG8388 16-Dec-15 2015_12 viable FBgn0051453 pch2 http://flybase.net/reports/FBgn0051453.html "FBgn0037595, FBgn0037596" protein_coding_gene 0005524=ATP binding "pch2, CG11743, CG11744, CG31453" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR001270=ClpA/B family, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG31453 16-Dec-15 2015_12 ENSDARG00000025043(trip13) YBR186W(PCH2) WBGene00008641(pch-2) ENSXETG00000013105(trip13) ENSMUSG00000021569(Trip13) ENSG00000071539(TRIP13) "viable,female fertile" DRSC14368 K -0.347241951 -0.136049348 -0.535069892 -0.275983088 0.179490429 1.850368478 FBgn0051202 ë±-Man-Ic ë±-Mannosidase class I c http://flybase.net/reports/FBgn0051202.html FBgn0039724 protein_coding_gene "0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, 0005509=calcium ion binding" 0016020=membrane "CG7880, dMas-2, CG31202, alpha-Mannosidase class I c, mas-2, alpha-Man-Ic" "IPR001382=Glycoside hydrolase, family 47" CG31202 16-Dec-15 2015_12 viable FBgn0039759 CG9733 http://flybase.net/reports/FBgn0039759.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0006952=defense response" "POAE-like Serine protease, proAE, c-SP10, pro-phenoloxidase AE, SP10, proPO-AE" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR001254=Serine proteases, trypsin domain" CG9733 16-Dec-15 2015_12 "lethal,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0263953 BG00915 http://flybase.net/reports/FBgn0263953.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0001682 l(1)ESHS3 lethal (1) ESHS3 http://flybase.net/reports/FBgn0001682.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024539 l(3)L1910 lethal (3) L1910 http://flybase.net/reports/FBgn0024539.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050001 CG30001 http://flybase.net/reports/FBgn0050001.html protein_coding_gene CG30001 16-Dec-15 2015_12 viable FBgn0086768 Pcmt Protein-L-isoaspartate (D-aspartate) O-methyltransferase http://flybase.net/reports/FBgn0086768.html "FBgn0015276, FBgn0015280, FBgn0022769" protein_coding_gene 0004719=protein-L-isoaspartate (D-aspartate) O-methyltransferase activity "0006464=cellular protein modification process, 0030091=protein repair, 0042742=defense response to bacterium" 0005737=cytoplasm "dPIMT, protein D-aspartyl, L-isoaspartyl O-methyltransferase, Protein isoaspartyl methyltransferase, CG2152, pcmt, Pimt, PIMT" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR000682=Protein-L-isoaspartate(D-aspartate) O-methyltransferase" CG2152 16-Dec-15 2015_12 "ENSDARG00000015201(pcmt),ENSDARG00000042848(pcmtl)" WBGene00003954(pcm-1) "ENSXETG00000015985(),ENSXETG00000017500(Q5BKH1_XENTR)" ENSMUSG00000019795(Pcmt1) ENSG00000120265(PCMT1) FBgn0001038 Fs(3)Ger Female sterile (3) Gerec http://flybase.net/reports/FBgn0001038.html gene "Fs(3)Sz9, Ger, Fs(3)Gerec" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus,female pronucleus" FBgn0023525 CG3191 http://flybase.net/reports/FBgn0023525.html "FBgn0040501, FBgn0042162" protein_coding_gene 0005215=transporter activity 0006810=transport 0005622=intracellular "62D9.a, EG:30B8.3, CG18842, BEST:GM01072" "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG3191 16-Dec-15 2015_12 "viable,fertile" FBgn0003163 pubescent pubescent http://flybase.net/reports/FBgn0003163.html gene pub 16-Dec-15 2015_12 "male sterile,visible" "microchaeta,adult abdomen,male,leg,metathoracic leg,wing vein L5,wing" FBgn0043484 l(3)66EFb lethal (3) 66EFb http://flybase.net/reports/FBgn0043484.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051822 CR31822 http://flybase.net/reports/FBgn0051822.html pseudogene_attribute CG31822 CR31822 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0002759 mit(1)9 mitotic 9 http://flybase.net/reports/FBgn0002759.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0034530 Rcd6 Reduction in Cnn dots 6 http://flybase.net/reports/FBgn0034530.html protein_coding_gene 0051297=centrosome organization 0000242=pericentriolar material "Rcd6, CG11175, Reduction in Cnn Dots 6" CG11175 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0040221 fs(2)AB00 fs(2)AB00 http://flybase.net/reports/FBgn0040221.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0264271 CR43771 http://flybase.net/reports/FBgn0264271.html non_protein_coding_gene CR43771 16-Dec-15 2015_12 FBgn0058075 CG40075 http://flybase.net/reports/FBgn0058075.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032444 CG5525 http://flybase.net/reports/FBgn0032444.html protein_coding_gene "0005524=ATP binding, 0051082=unfolded protein binding, 0042623=ATPase activity, coupled" "0022008=neurogenesis, 0090307=mitotic spindle assembly, 0006457=protein folding, 0007052=mitotic spindle organization, 0031122=cytoplasmic microtubule organization" "0005811=lipid particle, 0005829=cytosol, 0005875=microtubule associated complex, 0005832=chaperonin-containing T-complex" "Tcp-1delta, Tcp1-delta, CCT4, TCP-1, Q9VK69_DROME, Cct4" "IPR002423=Chaperonin Cpn60/TCP-1 family, IPR027410=TCP-1-like chaperonin intermediate domain, IPR012717=T-complex protein 1, delta subunit, IPR027409=GroEL-like apical domain, IPR027413=GroEL-like equatorial domain, IPR002194=Chaperonin TCP-1, conserved site, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1)" CG5525 16-Dec-15 2015_12 ENSDARG00000013475 YDL143W(CCT4) WBGene00000379(cct-4) ENSXETG00000002227(cct4) ENSMUSG00000007739(Cct4) ENSG00000115484(CCT4) "lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,neuroblast | larval stage" DRSC02865 K -0.520511445 -0.324373587 0.09977478 -0.688622533 1.641948162 0.304121477 FBgn0033524 Cyp49a1 Cyp49a1 http://flybase.net/reports/FBgn0033524.html FBgn0033525 protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0005739=mitochondrion" "cytochrome P450, 49a1, CG18377, Cyp49A1, Cyp49a1p, CG12894" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG18377 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" FBgn0032634 Rpb11 Rpb11 http://flybase.net/reports/FBgn0032634.html FBgn0064941 protein_coding_gene "0046983=protein dimerization activity, 0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0006366=transcription from RNA polymerase II promoter, 0006351=transcription, DNA-templated" "0005665=DNA-directed RNA polymerase II, core complex, 0005634=nucleus" "BcDNA:GM15177, RPB11, CG6840" "IPR008193=DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site, IPR009025=DNA-directed RNA polymerase, RBP11-like dimerisation domain" CG6840 16-Dec-15 2015_12 ENSDARG00000035146(polr2j) YOL005C(RPB11) WBGene00012187(rpb-11) ENSXETG00000001108(polr2j) ENSMUSG00000039771(Polr2j) "ENSG00000005075(POLR2J),ENSG00000168255(POLR2J3),ENSG00000197373,ENSG00000205236(UPK3BL)" lethal DRSC27111 K -0.403424413 -0.091395407 0.548895285 -0.309140762 1.069019604 1.81326517 FBgn0024997 CG2681 http://flybase.net/reports/FBgn0024997.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0007275=multicellular organismal development, 0006511=ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination" 0005634=nucleus "EG:100G10.2, 100G10.2" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR004162=E3 ubiquitin-protein ligase SIN-like, IPR013323=SIAH-type domain, IPR013010=Zinc finger, SIAH-type, IPR008974=TRAF-like, IPR018121=Seven-in-absentia protein, TRAF-like domain, IPR001841=Zinc finger, RING-type" CG2681 16-Dec-15 2015_12 viable FBgn0003372 Sgs1 Salivary gland secretion 1 http://flybase.net/reports/FBgn0003372.html protein_coding_gene "0005201=extracellular matrix structural constituent, 0005198=structural molecule activity" 0007594=puparial adhesion "0031012=extracellular matrix, 0005576=extracellular region" "sgs-1, Muc25B, CG3047, Mucin 25B, sgs1, Sgs, Sgs-1, salivary gland protein 1" CG3047 16-Dec-15 2015_12 larval stage | third instar larval salivary gland

larval stage | late third instar larval stage embryonic/larval salivary gland

"electrophoretic variant,viable" FBgn0084718 knk::Tsf2 knk::Tsf2 http://flybase.net/reports/FBgn0084718.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0016036 mei-P22 meiotic P22 http://flybase.net/reports/FBgn0016036.html protein_coding_gene "0042138=meiotic DNA double-strand break formation, 0007131=reciprocal meiotic recombination" 0000790=nuclear chromatin "CG14827, MEI-P22, Mei-P22" CG14827 16-Dec-15 2015_12 "meiotic cell cycle defective,partially lethal - majority die" FBgn0029950 CG9657 http://flybase.net/reports/FBgn0029950.html protein_coding_gene 0008507=sodium:iodide symporter activity 0055085=transmembrane transport 0016020=membrane "cg9657, dSLC5A9" "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG9657 16-Dec-15 2015_12 YHL016C(DUR3) WBGene00014092(ZK822.5) viable FBgn0032264 Lip4 Lipase 4 http://flybase.net/reports/FBgn0032264.html protein_coding_gene 0004806=triglyceride lipase activity "CG6113, dLip4, lipase 4, lipase4, dlip4" "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG6113 16-Dec-15 2015_12 ENSDARG00000018529(lipf) YKL140W(TGL1) ENSXETG00000009273(lipA) "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" "viable,fertile" FBgn0266782 CR45247 http://flybase.net/reports/FBgn0266782.html non_protein_coding_gene CR45247 16-Dec-15 2015_12 FBgn0029179 E(Khc)ek8 E(Khc)ek8 http://flybase.net/reports/FBgn0029179.html gene 16-Dec-15 2015_12 FBgn0250824 CG33655 http://flybase.net/reports/FBgn0250824.html "FBgn0053655, FBgn0063762, FBgn0045130" protein_coding_gene "NEST:bs30e09, BcDNA:AT03788, CR33655" CG33655 16-Dec-15 2015_12 FBgn0003105 PL(3)sp-W2 Polygenic locus sternopleural W2 http://flybase.net/reports/FBgn0003105.html gene "b, PL(3)sp[W2]" 16-Dec-15 2015_12 FBgn0033392 CG8027 http://flybase.net/reports/FBgn0033392.html protein_coding_gene "0016772=transferase activity, transferring phosphorus-containing groups" 0030154=cell differentiation 0016020=membrane Cg8027 "IPR000800=Notch domain, IPR021520=Stealth protein CR2, conserved region 2" CG8027 16-Dec-15 2015_12 ENSDARG00000030153(gnptab) ENSMUSG00000035311(Gnptab) ENSG00000111670(GNPTAB) viable FBgn0002730 mfs(3)73A male female sterile 73A http://flybase.net/reports/FBgn0002730.html gene 16-Dec-15 2015_12 "male sterile,recessive,female sterile" FBgn0265587 CR44414 http://flybase.net/reports/FBgn0265587.html non_protein_coding_gene lincRNA.81 CR44414 16-Dec-15 2015_12 FBgn0032457 CG15483 http://flybase.net/reports/FBgn0032457.html protein_coding_gene "0008532=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity" dibeta3GnT3 CG15483 16-Dec-15 2015_12 WBGene00008491(F01D4.9) viable FBgn0029102 anon-56Da anon-56Da http://flybase.net/reports/FBgn0029102.html gene EST B 16-Dec-15 2015_12 FBgn0263622 CR43631 http://flybase.net/reports/FBgn0263622.html non_protein_coding_gene CR43631 16-Dec-15 2015_12 FBgn0263527 mir-4908 mir-4908 stem loop http://flybase.net/reports/FBgn0263527.html miRNA_gene "dme-mir-4908, CR43512" CR43512 16-Dec-15 2015_12 FBgn0000870 fs(1)M65 female sterile (1) M65 http://flybase.net/reports/FBgn0000870.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0267054 CR45498 http://flybase.net/reports/FBgn0267054.html pseudogene_attribute CR45498 16-Dec-15 2015_12 FBgn0050235 tRNA:CR30235 transfer RNA:CR30235 http://flybase.net/reports/FBgn0050235.html FBgn0060167 tRNA_gene 0033417=CUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna28-LeuAAG, tRNA:L:AAG:AE002787-c, CR30235, AE002787.trna45-LeuAAG" CR30235 16-Dec-15 2015_12 FBgn0003113 pls palsied http://flybase.net/reports/FBgn0003113.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0065226 l(2)SH2209 lethal (2) SH2209 http://flybase.net/reports/FBgn0065226.html gene l(2)SH2 2209 16-Dec-15 2015_12 "lethal,recessive" FBgn0044036 Mod(rst)D252 Mod(rst)D252 http://flybase.net/reports/FBgn0044036.html gene 0001745=compound eye morphogenesis D252 16-Dec-15 2015_12 viable eye FBgn0062562 P25 P25 http://flybase.net/reports/FBgn0062562.html gene 16-Dec-15 2015_12 FBgn0036596 CG13045 http://flybase.net/reports/FBgn0036596.html protein_coding_gene CG13045 16-Dec-15 2015_12 FBgn0037144 CG7458 http://flybase.net/reports/FBgn0037144.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG7458 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "viable,fertile" FBgn0002657 mat(2)cell-F maternal effect cellularisation defect F http://flybase.net/reports/FBgn0002657.html gene 0007349=cellularization "mat(2)cellQC13, fs(2)QC13" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0033737 Nup54 Nucleoporin 54kD http://flybase.net/reports/FBgn0033737.html protein_coding_gene 0005487=nucleocytoplasmic transporter activity "0006607=NLS-bearing protein import into nucleus, 0006913=nucleocytoplasmic transport, 0006606=protein import into nucleus, 0006605=protein targeting" 0005643=nuclear pore "nup54, Nucleoporin 54, Nup53, CG8831" "IPR025712=Nucleoporin Nup54, alpha-helical domain, IPR024864=Nucleoporin Nup54/Nup57/Nup44" CG8831 16-Dec-15 2015_12 ENSDARG00000045348 YGR119C(NUP57) WBGene00003787(npp-1) ENSXETG00000024117(nup54) ENSMUSG00000034826(Nup54) ENSG00000138750(NUP54) "female fertile,viable,visible" trichogen cell FBgn0266826 CR45288 http://flybase.net/reports/FBgn0266826.html non_protein_coding_gene CR45288 16-Dec-15 2015_12 FBgn0004173 Mst84Db Male-specific RNA 84Db http://flybase.net/reports/FBgn0004173.html "FBgn0045209, FBgn0063353" protein_coding_gene "0007283=spermatogenesis, 0007288=sperm axoneme assembly" "Mst84, bs22c06.y1, mst(3)gl-2, NEST:bs22c06, Mstprox, Mst ORF, CG17934, Mst87D, Mst, BcDNA:AT08471" CG17934 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0028650 anon-55Eb anon-55Eb http://flybase.net/reports/FBgn0028650.html gene B-1450 16-Dec-15 2015_12 FBgn0039439 TwdlK TweedleK http://flybase.net/reports/FBgn0039439.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix CG6460 IPR004145=Domain of unknown function DUF243 CG6460 16-Dec-15 2015_12 viable FBgn0028368 l(1)10Ak lethal (1) 10Ak http://flybase.net/reports/FBgn0028368.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025173 l(2)38Dc lethal (2) 38Dc http://flybase.net/reports/FBgn0025173.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265531 CR44381 http://flybase.net/reports/FBgn0265531.html non_protein_coding_gene CR44381 16-Dec-15 2015_12 FBgn0058468 CR40468 http://flybase.net/reports/FBgn0058468.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0262069 EG79 http://flybase.net/reports/FBgn0262069.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034457 Ir56c Ionotropic receptor 56c http://flybase.net/reports/FBgn0034457.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "DmelIR56c, ionotropic receptor 56c, CG15122, IR56c" CG15122 16-Dec-15 2015_12 viable FBgn0037288 CG14661 http://flybase.net/reports/FBgn0037288.html protein_coding_gene CT34439 IPR010562=Haemolymph juvenile hormone binding CG14661 16-Dec-15 2015_12 viable FBgn0013979 Har63 Har63 http://flybase.net/reports/FBgn0013979.html gene har63 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0022287 l(2)10333 lethal (2) 10333 http://flybase.net/reports/FBgn0022287.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038020 GstD9 Glutathione S transferase D9 http://flybase.net/reports/FBgn0038020.html protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "gstD9, GSTD9, CG10091, DmGstd9, gstd9, DmGSTD9, GST-D9" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like" CG10091 16-Dec-15 2015_12 YNL229C(URE2) viable FBgn0028114 l(3)S064316b lethal (3) S064316b http://flybase.net/reports/FBgn0028114.html gene "l(3)S064316, 0643/16" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0034691 Synj Synaptojanin http://flybase.net/reports/FBgn0034691.html protein_coding_gene "0000166=nucleotide binding, 0004445=inositol-polyphosphate 5-phosphatase activity, 0046030=inositol trisphosphate phosphatase activity" "0007269=neurotransmitter secretion, 0048488=synaptic vesicle endocytosis, 0016311=dephosphorylation, 0048790=maintenance of presynaptic active zone structure, 0050803=regulation of synapse structure or activity, 0046856=phosphatidylinositol dephosphorylation" "0012506=vesicle membrane, 0043195=terminal bouton" "Synaptojanin, CG6562, IPP, synj, synaptojanin, Synj" "IPR000300=Inositol polyphosphate-related phosphatase, IPR002013=SAC domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR005135=Endonuclease/exonuclease/phosphatase, IPR015047=Domain of unknown function DUF1866" CG6562 16-Dec-15 2015_12 ENSDARG00000025011(synj1) "YOR109W(INP53),YNL106C(INP52)" WBGene00006763(unc-26) ENSMUSG00000022973(Synj1) ENSG00000159082(SYNJ1) "neuroanatomy defective,neurophysiology defective,viable,lethal,recessive,locomotor behavior defective,somatic clone,endocytosis defective" "photoreceptor & synaptic vesicle,neuromuscular junction & synaptic vesicleX58-7),NMJ bouton,supernumerary,presynaptic active zoneX58-7),dense body,bouton,synaptic vesicle | somatic clone" FBgn0016814 l(1)L17 lethal (1) L17 http://flybase.net/reports/FBgn0016814.html gene L17 16-Dec-15 2015_12 "lethal,recessive" FBgn0060612 l(3)S090214 lethal (3) S090214 http://flybase.net/reports/FBgn0060612.html gene 0902/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0026394 Or24a Odorant receptor 24a http://flybase.net/reports/FBgn0026394.html FBgn0031586 protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "Olfactory receptor 24D.1, CG11767, Or24D.1, DOR24D.1, 24D.1, DOR48, 24a" "IPR004117=Olfactory receptor, Drosophila" CG11767 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0267264 CR45700 http://flybase.net/reports/FBgn0267264.html non_protein_coding_gene CR45700 16-Dec-15 2015_12 FBgn0035400 CG11537 http://flybase.net/reports/FBgn0035400.html protein_coding_gene 0015144=carbohydrate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain, IPR001958=Tetracycline resistance protein, TetA/multidrug resistance protein MdtG, IPR005829=Sugar transporter, conserved site" CG11537 16-Dec-15 2015_12 "ENSDARG00000013117(hiat1a),ENSDARG00000043055(hiat1b),ENSDARG00000010023(LOC557306),ENSDARG00000030129" WBGene00020798(T25D3.4) "ENSXETG00000006560(BC088481.1),ENSXETG00000013200(hiat1)" "ENSMUSG00000027958(Hiat1),ENSMUSG00000038212(Hiatl1)" "ENSG00000156875(HIAT1),ENSG00000148110(HIATL1)" viable FBgn0030802 DENR Density regulated protein http://flybase.net/reports/FBgn0030802.html protein_coding_gene "0003743=translation initiation factor activity, 0003729=mRNA binding" "0008284=positive regulation of cell proliferation, 0035076=ecdysone receptor-mediated signaling pathway, 0046628=positive regulation of insulin receptor signaling pathway, 0045948=positive regulation of translational initiation, 0002188=translation reinitiation" CG9099 "IPR005873=Density-regulated protein DRP1, IPR001950=Translation initiation factor SUI1" CG9099 16-Dec-15 2015_12 ENSDARG00000037229(denr) YJR014W(TMA22) WBGene00012932(Y47D3A.21) ENSXETG00000005791(denr) ENSMUSG00000023106(Denr) ENSG00000139726(DENR) "viable,visible" trichogen cell DRSC20151 K -0.237522013 -0.636198994 0.046707445 0.261215173 2.1585028 0.34994798 FBgn0000600 E(var)88D Enhancer of variegation 88D http://flybase.net/reports/FBgn0000600.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant,lethal,recessive" FBgn0264848 vih vihar http://flybase.net/reports/FBgn0264848.html "FBgn0027936, FBgn0036293, FBgn0046375, FBgn0046376, FBgn0046377, FBgn0060486" protein_coding_gene "0061631=ubiquitin conjugating enzyme activity, 0004842=ubiquitin-protein transferase activity" "0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0045842=positive regulation of mitotic metaphase/anaphase transition, 2000600=positive regulation of cyclin catabolic process, 0010458=exit from mitosis" "0000151=ubiquitin ligase complex, 0031616=spindle pole centrosome, 0005634=nucleus" "1105/01, vihar, anon-WO0172774.55, l(3)S110501, anon-WO0172774.54, CG10682, lethal (3) S110501, anon-WO0172774.56" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site" CG10682 16-Dec-15 2015_12 ENSDARG00000035770(zgc:123190) YOR339C(UBC11) ENSXETG00000014881(UBE2C) ENSMUSG00000001403(Ube2c) ENSG00000175063(UBE2C) DRSC09778 IE 1.133838337 -2.147923797 2.834704331 -4.474777211 -0.99294062 -0.248790768 FBgn0020494 D59 D59 http://flybase.net/reports/FBgn0020494.html gene unnamed 16-Dec-15 2015_12 FBgn0022030 l(2)k08816 lethal (2) k08816 http://flybase.net/reports/FBgn0022030.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267013 CR45457 http://flybase.net/reports/FBgn0267013.html non_protein_coding_gene CR45457 16-Dec-15 2015_12 FBgn0026014 UC119 UC119 http://flybase.net/reports/FBgn0026014.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic epidermis,embryonic head" FBgn0038744 CG4733 http://flybase.net/reports/FBgn0038744.html protein_coding_gene "0005509=calcium ion binding, 0008601=protein phosphatase type 2A regulator activity" 0046331=lateral inhibition "dPR72, PR72, PR-72, PP2A-B'', dPP2A-PR72, B'', PP2A like" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG4733 16-Dec-15 2015_12 WBGene00015548(C06G1.5) ENSXETG00000018927(PPP2R3A) ENSMUSG00000043154(Ppp2r3a) ENSG00000073711(PPP2R3A) "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0267239 CR45679 http://flybase.net/reports/FBgn0267239.html non_protein_coding_gene CR45679 16-Dec-15 2015_12 FBgn0085225 CG34196 http://flybase.net/reports/FBgn0085225.html protein_coding_gene CG34196 16-Dec-15 2015_12 FBgn0062617 Mod(var)1227 Mod(var)1227 http://flybase.net/reports/FBgn0062617.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1227 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,partially lethal - majority die,recessive" FBgn0260312 GSd306 http://flybase.net/reports/FBgn0260312.html gene 16-Dec-15 2015_12 lethal FBgn0058006 CG40006 http://flybase.net/reports/FBgn0058006.html "FBan0040006, FBgn0047064" protein_coding_gene 0007155=cell adhesion 0016020=membrane BcDNA:RE68569 IPR002159=CD36 antigen CG40006 16-Dec-15 2015_12 "WBGene00013039(scav-3),WBGene00013578(scav-2)" FBgn0259966 Sfp51E Seminal fluid protein 51E http://flybase.net/reports/FBgn0259966.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 51E, CG42476" CG42476 16-Dec-15 2015_12 FBgn0061054 l(3)S023014b lethal (3) S023014b http://flybase.net/reports/FBgn0061054.html gene 0230/14 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004737 l(3)85Dd lethal (3) 85Dd http://flybase.net/reports/FBgn0004737.html gene 16-Dec-15 2015_12 lethal FBgn0060305 l(3)S148801a lethal (3) S148801a http://flybase.net/reports/FBgn0060305.html gene 1488/01 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039788 Rpt6R Regulatory particle triple-A ATPase 6-related http://flybase.net/reports/FBgn0039788.html protein_coding_gene "0016887=ATPase activity, 0016787=hydrolase activity, 0005524=ATP binding" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0022008=neurogenesis" "0005737=cytoplasm, 0008540=proteasome regulatory particle, base subcomplex, 0005875=microtubule associated complex" "Rpt6, Rpt6b, DmCG2241, S8, CG2241, Dm_Rpt6b" "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005937=26S proteasome subunit P45, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain" CG2241 16-Dec-15 2015_12 YGL048C(RPT6) "WBGene00004506(rpt-6),WBGene00018991(F56F11.4)" "visible,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" DRSC15431 I -0.730885546 1.693128669 -0.971746966 0.752329121 -0.172286694 0.562557341 FBgn0010340 140up upstream of RpII140 http://flybase.net/reports/FBgn0010340.html FBgn0004843 protein_coding_gene 0007275=multicellular organismal development "DmRP140-upstream, DmRP140up, l(3)88Ba, l(3)Z6, CG9852, unnamed" IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG9852 16-Dec-15 2015_12 WBGene00021421(Y38F2AR.3) ENSMUSG00000002846(4930455C21Rik) ENSG00000113845(TIMMDC1) adult stage "lethal,recessive,viable,visible" trichogen cell FBgn0025485 l(3)88Ad lethal (3) 88Ad http://flybase.net/reports/FBgn0025485.html gene 16-Dec-15 2015_12 FBgn0085780 CR40976 http://flybase.net/reports/FBgn0085780.html FBan0040976 rRNA_gene 16-Dec-15 2015_12 FBgn0023156 Su(mg)2-3 Suppressor of modifier of gypsy 2-3 http://flybase.net/reports/FBgn0023156.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024215 l(3)E2 lethal (3) E2 http://flybase.net/reports/FBgn0024215.html gene 16-Dec-15 2015_12 lethal FBgn0028034 l(3)S101712 lethal (3) S101712 http://flybase.net/reports/FBgn0028034.html gene 1017/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0033062 Ars2 http://flybase.net/reports/FBgn0033062.html FBgn0062198 protein_coding_gene "0045071=negative regulation of viral genome replication, 0033168=conversion of ds siRNA to ss siRNA involved in RNA interference, 0035195=gene silencing by miRNA, 0046685=response to arsenic-containing substance, 0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome, 0050829=defense response to Gram-negative bacterium" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "Ars2, CG7843, anon-WO0118547.166, Arsenic resistance protein 2" "IPR007042=Arsenite-resistance protein 2, IPR021933=Protein of unknown function DUF3546" CG7843 16-Dec-15 2015_12 ENSDARG00000017762(srrt) WBGene00017085(E01A2.2) ENSMUSG00000037364(Srrt) ENSG00000087087(SRRT) "lethal,immune response defective,heat sensitive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,female fertile,recessive" "embryonic/larval neuroblast,mesothoracic tergum" FBgn0028422 GluRIID Glutamate receptor IID http://flybase.net/reports/FBgn0028422.html "FBgn0038817, FBgn0061176, FBgn0082321" protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity, 0004970=ionotropic glutamate receptor activity" "0006811=ion transport, 0043179=rhythmic excitation, 0030510=regulation of BMP signaling pathway, 0007274=neuromuscular synaptic transmission, 0035249=synaptic transmission, glutamatergic" "0097482=muscle cell postsynaptic density, 0008328=ionotropic glutamate receptor complex" "gluRIID, bad reception, GluRIID, KaiRIA, GluR-IID, DGluRIID, GluRIA, Kai-RIA, DKaiR-IA, CT13538, brec, CG18039, DmelGluRIID" "IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001508=Ionotropic glutamate receptor, metazoa, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I" CG18039 16-Dec-15 2015_12 "paralytic,recessive,neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,partially,viable" "embryonic/larval neuromuscular junction,central nervous system & motor neuron,neuromuscular junction,NMJ bouton" FBgn0024244 drm drumstick http://flybase.net/reports/FBgn0024244.html FBgn0031551 protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0045893=positive regulation of transcription, DNA-templated, 0007440=foregut morphogenesis, 0016348=imaginal disc-derived leg joint morphogenesis, 0048565=digestive tract development, 0045892=negative regulation of transcription, DNA-templated, 0048617=embryonic foregut morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007442=hindgut morphogenesis, 0048619=embryonic hindgut morphogenesis" "drum, CG10016" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG10016 16-Dec-15 2015_12 " larval stage | third instar , pupal stage " " ventral thoracic disc | restricted

, leg | restricted

" "lethal,recessive,visible,somatic clone" "embryonic hindgut,embryonic proventriculus,embryonic/larval proventriculus,embryonic/larval hindgut,embryonic large intestine,embryonic dorsal epidermis,keyhole structure,embryonic foregut,embryonic small intestine,leg & adult cuticle | somatic clone,eye disc,somatic clone,disc epithelium proper & dorsal mesothoracic disc | somatic clone,wing hinge primordium,scutellum" FBgn0014327 l(3)ry60 lethal (3) ry60 http://flybase.net/reports/FBgn0014327.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035896 CG6983 http://flybase.net/reports/FBgn0035896.html protein_coding_gene 0005829=cytosol IPR026794=Uncharacterised protein family UPF0687 CG6983 16-Dec-15 2015_12 ENSXETG00000012747(Q68FA2_XENTR) ENSMUSG00000027327(1700037H04Rik) viable FBgn0052202 CG32202 http://flybase.net/reports/FBgn0052202.html "FBgn0040789, FBtr0075051, FBpp0074818" protein_coding_gene CG13381 CG32202 16-Dec-15 2015_12 ENSXETG00000003165(tfpt) viable FBgn0011297 l(2)not lethal (2) neighbor of tid http://flybase.net/reports/FBgn0011297.html protein_coding_gene "0016758=transferase activity, transferring hexosyl groups" "0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0030176=integral component of endoplasmic reticulum membrane" "CG4084, ntid, lethal(2) neighbour of 1(2)tid, dAlg3, cDNA 10F, 1(2) not" "IPR007873=Glycosyltransferase, ALG3" CG4084 16-Dec-15 2015_12 ENSDARG00000053155(alg3) YBL082C(ALG3) WBGene00010720(K09E4.2) ENSXETG00000017280(ALG3) ENSMUSG00000033809(Alg3) ENSG00000214160(ALG3) embryonic stage && larval stage embryonic stage "viable,fertile" FBgn0020252 rubymine rubymine http://flybase.net/reports/FBgn0020252.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0015576 ë±-Est8 ë±-Esterase-8 http://flybase.net/reports/FBgn0015576.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "alphaE8, fragment I, unnamed, DmalphaE8, Est8, CG1121, aE8, alpha-Est8, I" "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site" CG1121 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" FBgn0003211 rbl reduced bristles http://flybase.net/reports/FBgn0003211.html FBgn0003672 gene "tbs, rdb, reduced bristle, thin bristles, tiny bristles, Ho" 16-Dec-15 2015_12 "viable,fertile,visible,recessive" macrochaeta FBgn0019867 anon-B5 anon-B5 http://flybase.net/reports/FBgn0019867.html gene B5 16-Dec-15 2015_12 FBgn0025645 CG3598 http://flybase.net/reports/FBgn0025645.html protein_coding_gene EG:100G7.3 CG3598 16-Dec-15 2015_12 viable FBgn0024556 EfTuM Elongation factor Tu mitochondrial http://flybase.net/reports/FBgn0024556.html FBgn0033847 protein_coding_gene "0003924=GTPase activity, 0003746=translation elongation factor activity, 0005525=GTP binding" "0007030=Golgi organization, 0000278=mitotic cell cycle, 0008283=cell proliferation, 0006414=translational elongation" 0005739=mitochondrion "CG6050, ELONGATION FACTOR Tu MITOCHONDRIAL, l(3)L4569, efTuM, mtEF-Tu, eftu-M" "IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR004541=Translation elongation factor EFTu/EF1A, bacterial/organelle, IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR004160=Translation elongation factor EFTu/EF1A, C-terminal, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR031157=Tr-type G domain, conserved site" CG6050 16-Dec-15 2015_12 ENSDARG00000041088(tufm) YOR187W(TUF1) WBGene00007000(tufm-1) ENSXETG00000028019() "ENSMUSG00000073838(Tufm),ENSMUSG00000030735(Gm9755)" ENSG00000178952(TUFM) "lethal,recessive" "digestive system,somatic muscle" DRSC29468 K 0.019710674 0.249627686 -0.178120308 0.290771474 -0.771654608 1.629753792 FBgn0267717 CR46050 http://flybase.net/reports/FBgn0267717.html non_protein_coding_gene Mgn1719 CR46050 16-Dec-15 2015_12 FBgn0016828 l(1)MZ15 lethal (1) MZ15 http://flybase.net/reports/FBgn0016828.html gene M15 16-Dec-15 2015_12 "lethal,recessive" FBgn0028949 CG15254 http://flybase.net/reports/FBgn0028949.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" 0006508=proteolysis "BG:BACR44L22.2, BACcr44L22.2" "IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR001506=Peptidase M12A, astacin" CG15254 16-Dec-15 2015_12 viable DRSC01870 E -0.509680804 -0.425045421 -1.701933071 0.453752207 0.28012236 0.379817054 FBgn0083148 S(smoDN)395 Suppressor of smoDN 395 http://flybase.net/reports/FBgn0083148.html gene 16-Dec-15 2015_12 FBgn0050454 tRNA:CR30454 transfer RNA:CR30454 http://flybase.net/reports/FBgn0050454.html FBgn0060243 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002787.trna3-GluCTC, CR30454, chr2R.trna61-GluCTC, tRNA:E:CTC:AE002787-a" CR30454 16-Dec-15 2015_12 FBgn0020370 TppII tripeptidyl-peptidase II http://flybase.net/reports/FBgn0020370.html "FBgn0021861, FBgn0062227" protein_coding_gene "0008240=tripeptidyl-peptidase activity, 0008238=exopeptidase activity, 0004252=serine-type endopeptidase activity" "0006508=proteolysis, 0051260=protein homooligomerization" "0005615=extracellular space, 0005739=mitochondrion, 0005737=cytoplasm" "dTPPII, CG3991, TPP2, Tripeptidyl-peptidase II, TPPII, anon-WO0118547.127, dTPP II, Tripeptidylpeptidase II, tripeptidyl peptidase II, l(2)k14301, TPP II" "IPR015500=Peptidase S8, subtilisin-related, IPR022232=Peptidase S8A, tripeptidyl peptidase II, arthropoda, IPR023828=Peptidase S8, subtilisin, Ser-active site, IPR000209=Peptidase S8/S53 domain, IPR022229=Peptidase S8A, tripeptidyl peptidase II, IPR022398=Peptidase S8, subtilisin, His-active site" CG3991 16-Dec-15 2015_12 WBGene00017686(F21H12.6) ENSXETG00000002749(TPP2) ENSMUSG00000041763(Tpp2) ENSG00000134900(TPP2) "lethal,recessive,viable,visible" trichogen cell FBgn0014302 l(3)94Fa lethal (3) 94Fa http://flybase.net/reports/FBgn0014302.html gene unnamed 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" eye FBgn0065902 l(2)SH0199 lethal (2) SH0199 http://flybase.net/reports/FBgn0065902.html gene l(2)SH2 0199 16-Dec-15 2015_12 "lethal,recessive" FBgn0038765 CG4424 http://flybase.net/reports/FBgn0038765.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4424 16-Dec-15 2015_12 WBGene00004335(ref-2) "ENSMUSG00000046792(Zfp787),ENSMUSG00000054716(Zfp771),ENSMUSG00000042097(Zfp239)" viable FBgn0015970 l(2)55Db lethal (2) 55Db http://flybase.net/reports/FBgn0015970.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023144 T:Khc-606 T:Khc-606 http://flybase.net/reports/FBgn0023144.html engineered_tag T:Khc 16-Dec-15 2015_12 FBgn0031428 CG9886 http://flybase.net/reports/FBgn0031428.html protein_coding_gene 0008887=glycerate kinase activity 0006468=protein phosphorylation 0005737=cytoplasm "IPR007835=MOFRL domain, IPR025286=MOFRL-associated domain" CG9886 16-Dec-15 2015_12 ENSDARG00000060120(zgc:153346) WBGene00015733(C13B9.2) ENSMUSG00000020258(Glyctk) ENSG00000168237(GLYCTK) viable FBgn0003264 Rnase1 Ribonuclease 1 http://flybase.net/reports/FBgn0003264.html gene 0004540=ribonuclease activity "acid RNase, Pacman" 16-Dec-15 2015_12 FBgn0035857 CG8006 http://flybase.net/reports/FBgn0035857.html protein_coding_gene CG8006 16-Dec-15 2015_12 viable FBgn0003537 Stp-1 Strapped on 1 http://flybase.net/reports/FBgn0003537.html gene Strapped in chromosome 1 16-Dec-15 2015_12 "wing margin,male" FBgn0061519 blairy blairy http://flybase.net/reports/FBgn0061519.html gene 0001751=compound eye photoreceptor cell differentiation 16-Dec-15 2015_12 FBgn0037589 Obp85a Odorant-binding protein 85a http://flybase.net/reports/FBgn0037589.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp85a, CG11732" CG11732 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0062582 Mod(var)234 Mod(var)234 http://flybase.net/reports/FBgn0062582.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 234 16-Dec-15 2015_12 "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,lethal" FBgn0267808 CR46133 http://flybase.net/reports/FBgn0267808.html non_protein_coding_gene CR46133 16-Dec-15 2015_12 FBgn0085618 CG41328 http://flybase.net/reports/FBgn0085618.html FBan0041328 protein_coding_gene 16-Dec-15 2015_12 FBgn0040010 CG17493 http://flybase.net/reports/FBgn0040010.html "FBan0017493, FBgn0058016" protein_coding_gene 0005509=calcium ion binding "0005856=cytoskeleton, 0005815=microtubule organizing center" CG40016 "IPR002048=EF-hand domain, IPR029527=Centrin-1, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG17493 16-Dec-15 2015_12 ENSDARG00000041215 YOR257W(CDC31) "ENSXETG00000018443(cetn2),ENSXETG00000001591()" "ENSMUSG00000050996(Cetn1),ENSMUSG00000031347(Cetn2)" "ENSG00000147400(CETN2),ENSG00000177143(CETN1)" viable FBgn0027781 Su(y)P31 Su(y)P31 http://flybase.net/reports/FBgn0027781.html gene Su(y)[P31] 16-Dec-15 2015_12 FBgn0020896 Su(osk)G28 Suppressor of oskar G28 http://flybase.net/reports/FBgn0020896.html gene G28 16-Dec-15 2015_12 FBgn0265654 CR44461 http://flybase.net/reports/FBgn0265654.html non_protein_coding_gene lincRNA.295 CR44461 16-Dec-15 2015_12 FBgn0040106 lectin-21Cb lectin-21Cb http://flybase.net/reports/FBgn0040106.html FBgn0031271 protein_coding_gene "0030246=carbohydrate binding, 0005537=mannose binding" "AC004573b, Lectin21Cb, CG13686, AC 004573B" "IPR016186=C-type lectin-like, IPR016187=C-type lectin fold, IPR001304=C-type lectin" CG13686 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000008874(Clec3a),ENSMUSG00000025784(Clec3b),ENSMUSG00000004473(Clec11a)" ENSG00000163815(CLEC3B) viable FBgn0022300 l(1)L9.8 lethal (1) L9.8 http://flybase.net/reports/FBgn0022300.html gene L9.8 16-Dec-15 2015_12 "lethal,recessive" FBgn0011798 l(3)rI809 lethal (3) rI809 http://flybase.net/reports/FBgn0011798.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031738 CG9171 http://flybase.net/reports/FBgn0031738.html protein_coding_gene "0008109=N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity" 0002121=inter-male aggressive behavior dibeta3GnT2 CG9171 16-Dec-15 2015_12 WBGene00008491(F01D4.9) "viable,body color defective,behavior defective,recessive,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,fertile" mesothoracic tergum FBgn0005003 darkener-of-white-eosin darkener of white-eosin http://flybase.net/reports/FBgn0005003.html gene dark 16-Dec-15 2015_12 eye FBgn0033515 Ir47a Ionotropic receptor 47a http://flybase.net/reports/FBgn0033515.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG12900, CG12900/CG34363, IR47a, DmelIR47a, ionotropic receptor 47a" CG12900 16-Dec-15 2015_12 viable FBgn0005219 l(3)ET13 lethal Elaine Tasaka 13 http://flybase.net/reports/FBgn0005219.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0032084 CG13101 http://flybase.net/reports/FBgn0032084.html protein_coding_gene CG13101 16-Dec-15 2015_12 viable intersegmental nerve FBgn0265919 CR44708 http://flybase.net/reports/FBgn0265919.html non_protein_coding_gene lincRNA.1016 CR44708 16-Dec-15 2015_12 FBgn0084008 CR41443 http://flybase.net/reports/FBgn0084008.html FBan0041443 non_protein_coding_gene "chr2R_1141286_1142866.0, CG41443" CR41443 16-Dec-15 2015_12 FBgn0001872 l(1)XN52 lethal (1) XN52 http://flybase.net/reports/FBgn0001872.html gene 16-Dec-15 2015_12 FBgn0265074 CR44185 http://flybase.net/reports/FBgn0265074.html non_protein_coding_gene CR44185 16-Dec-15 2015_12 FBgn0001781 l(1)M70 lethal (1) M70 http://flybase.net/reports/FBgn0001781.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0259470 C705 http://flybase.net/reports/FBgn0259470.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0086043 snoRNA:Me18S-C1024 http://flybase.net/reports/FBgn0086043.html snoRNA_gene "Me18S-Cm1024, CR34672" CR34672 16-Dec-15 2015_12 FBgn0038092 beat-Vb beat-Vb http://flybase.net/reports/FBgn0038092.html "FBgn0038093, FBgn0051298" protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "CG14386, Beat-Vb, CG31298, CG14385, beat Vb" "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG31298 16-Dec-15 2015_12 "ENSDARG00000068114(si:ch211-89p1.1),ENSDARG00000017320(f11r),ENSDARG00000058996,ENSDARG00000061794(jam3),ENSDARG00000063421" "viable,fertile" DRSC12940 E 1.417581411 -0.120508528 1.443371841 1.828473614 0.042311771 -0.452172504 FBgn0005438 l(1)v75 lethal (1) v75 http://flybase.net/reports/FBgn0005438.html gene l(1)75 16-Dec-15 2015_12 FBgn0000852 fs(1)M41 female sterile (1) M41 http://flybase.net/reports/FBgn0000852.html gene unnamed 16-Dec-15 2015_12 "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0011114 l(1)Q75 lethal (1) Q75 http://flybase.net/reports/FBgn0011114.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0085473 CG34444 http://flybase.net/reports/FBgn0085473.html "FBan0030070, FBgn0033930, FBgn0050070" protein_coding_gene CG30070 IPR006631=Protein of unknown function DM4/12 CG34444 16-Dec-15 2015_12 viable FBgn0065156 l(3)SH050 lethal (3) SH050 http://flybase.net/reports/FBgn0065156.html gene l(2)SH3 050 16-Dec-15 2015_12 "lethal,recessive" FBgn0050265 CG30265 http://flybase.net/reports/FBgn0050265.html FBgn0034781 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane CG11682 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG30265 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,fertile" FBgn0002243 l(3)68Ce lethal (3) 68Ce http://flybase.net/reports/FBgn0002243.html gene "l(3)rsg4, rsg4, rose-gespleten region interval 4" 16-Dec-15 2015_12 lethal FBgn0065613 l(2)SH0827 lethal (2) SH0827 http://flybase.net/reports/FBgn0065613.html gene l(2)SH2 0827 16-Dec-15 2015_12 "lethal,recessive" FBgn0065483 l(2)SH1275 lethal (2) SH1275 http://flybase.net/reports/FBgn0065483.html gene l(2)SH2 1275 16-Dec-15 2015_12 "lethal,recessive" FBgn0267636 CR45974 http://flybase.net/reports/FBgn0267636.html non_protein_coding_gene CR45974 16-Dec-15 2015_12 FBgn0061210 Egfr::htl Egfr::htl http://flybase.net/reports/FBgn0061210.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0265813 CR44602 http://flybase.net/reports/FBgn0265813.html non_protein_coding_gene lincRNA.156 CR44602 16-Dec-15 2015_12 FBgn0262528 CG43082 http://flybase.net/reports/FBgn0262528.html protein_coding_gene IPR003475=Insect protein of unknown function CG43082 16-Dec-15 2015_12 FBgn0265144 CR44213 http://flybase.net/reports/FBgn0265144.html non_protein_coding_gene CR44213 16-Dec-15 2015_12 FBgn0002117 l(2)Co lethal (2) Corato http://flybase.net/reports/FBgn0002117.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005259 l(3)SG79 lethal (3) SG79 http://flybase.net/reports/FBgn0005259.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0015979 l(2)PC4-E lethal (2) PC4-E http://flybase.net/reports/FBgn0015979.html gene l(2)PC4-H 16-Dec-15 2015_12 "lethal,recessive" FBgn0058177 CG40177 http://flybase.net/reports/FBgn0058177.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035337 CG15877 http://flybase.net/reports/FBgn0035337.html protein_coding_gene IPR019327=Protein of unknown function DUF2373 CG15877 16-Dec-15 2015_12 ENSDARG00000045254(LOC567594) ENSMUSG00000053553(3110082I17Rik) viable FBgn0262773 Su(E1)-G http://flybase.net/reports/FBgn0262773.html gene 16-Dec-15 2015_12 FBgn0040049 CG17427 http://flybase.net/reports/FBgn0040049.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004819 fs(2)ltoDG25 female sterile (2) ltoDG25 http://flybase.net/reports/FBgn0004819.html gene 0007300=ovarian nurse cell to oocyte transport DG25 16-Dec-15 2015_12 female sterile FBgn0085442 NKAIN "Na,K-ATPase Interacting" http://flybase.net/reports/FBgn0085442.html "FBgn0061524, FBgn0052836, FBgn0035075" protein_coding_gene 0005515=protein binding 0002028=regulation of sodium ion transport "CG9047, dNKAIN, CG32836, CG34413, anon-WO0118547.94" "IPR008516=Na,K-Atpase Interacting protein" CG34413 16-Dec-15 2015_12 FBgn0260291 GSd408 http://flybase.net/reports/FBgn0260291.html gene 16-Dec-15 2015_12 lethal FBgn0060595 l(3)S092016b lethal (3) S092016b http://flybase.net/reports/FBgn0060595.html gene 0920/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0065198 l(2)SH2315 lethal (2) SH2315 http://flybase.net/reports/FBgn0065198.html gene l(2)SH2 2315 16-Dec-15 2015_12 "lethal,recessive" FBgn0086288 GS2285 http://flybase.net/reports/FBgn0086288.html gene 2285 16-Dec-15 2015_12 FBgn0060352 l(3)S141914 lethal (3) S141914 http://flybase.net/reports/FBgn0060352.html gene 1419/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0021978 l(2)k09920 lethal (2) k09920 http://flybase.net/reports/FBgn0021978.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266655 CR45162 http://flybase.net/reports/FBgn0266655.html non_protein_coding_gene CR45162 16-Dec-15 2015_12 FBgn0039618 CG14520 http://flybase.net/reports/FBgn0039618.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038927 CG6015 http://flybase.net/reports/FBgn0038927.html protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "CDC40, prp17" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat" CG6015 16-Dec-15 2015_12 ENSDARG00000041226(cdc40) YDR364C(CDC40) WBGene00018625(prp-17) ENSXETG00000021312(cdc40) ENSMUSG00000038446(Cdc40) ENSG00000168438(CDC40) "neuroanatomy defective,lethal" "presumptive embryonic/larval peripheral nervous system,ventral midline neuron & axon,longitudinal connective,ventral nerve cord commissure,ventral nerve cord" DRSC15948 IE 0.647497706 3.656099761 1.925479591 -0.30404324 -1.266909177 1.150248943 FBgn0038980 Octë_1R Octopamine ë_1 receptor http://flybase.net/reports/FBgn0038980.html "FBgn0046516, FBgn0046517" protein_coding_gene "0004935=adrenergic receptor activity, 0008227=G-protein coupled amine receptor activity, 0004989=octopamine receptor activity" "0010579=positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway, 0051482=positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, 0045886=negative regulation of synaptic growth at neuromuscular junction" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "Octbeta1R, Dmoa2, DmCG6919, oa2, Oa2, octbeta1R, OA2, anon-WO0170980.68, DmOctBeta1R, CG6919, DmOctbeta1R, OctBeta1, octopamine receptor 2, anon-WO0170980.67" "IPR002233=Adrenoceptor family, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG6919 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective,locomotor behavior defective" "embryonic/larval neuromuscular junction | third instar larval stage,type II bouton,supernumerary | third instar larval stage,type I bouton,embryonic/larval neuromuscular junction,supernumerary" FBgn0015355 anon-99Cd anon-99Cd http://flybase.net/reports/FBgn0015355.html gene 16-Dec-15 2015_12 FBgn0001581 l(1)AL3 lethal (1) AL3 http://flybase.net/reports/FBgn0001581.html gene 16-Dec-15 2015_12 "lethal,short lived" FBgn0052987 CG32987 http://flybase.net/reports/FBgn0052987.html FBgn0032071 protein_coding_gene CG15866 CG32987 16-Dec-15 2015_12 DRSC22373 IK 0.550298323 -1.502227948 -0.240381416 0.311011642 0.729869589 1.800283973 FBgn0085507 CG40660 http://flybase.net/reports/FBgn0085507.html FBan0040660 protein_coding_gene 16-Dec-15 2015_12 FBgn0019840 ato::sc ato::sc http://flybase.net/reports/FBgn0019840.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 visible "chordotonal organ of wing,ectopic,wing & external sensory organhs.PB,external sensory organ" FBgn0060406 l(3)S130610 lethal (3) S130610 http://flybase.net/reports/FBgn0060406.html gene 1306/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0029951 CG11369 http://flybase.net/reports/FBgn0029951.html protein_coding_gene CG11369 16-Dec-15 2015_12 viable FBgn0260430 CG42525 http://flybase.net/reports/FBgn0260430.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR002557=Chitin binding domain" CG42525 16-Dec-15 2015_12 FBgn0022721 sour-grapes sour grapes http://flybase.net/reports/FBgn0022721.html gene 16-Dec-15 2015_12 FBgn0030412 Tomosyn Tomosyn ortholog http://flybase.net/reports/FBgn0030412.html "FBgn0030413, FBgn0030414, FBgn0062437" protein_coding_gene "0017075=syntaxin-1 binding, 0000149=SNARE binding" "0016079=synaptic vesicle exocytosis, 0007616=long-term memory, 0007269=neurotransmitter secretion, 1900073=regulation of neuromuscular synaptic transmission, 0006887=exocytosis, 0006893=Golgi to plasma membrane transport, 0016082=synaptic vesicle priming, 0022008=neurogenesis, 0007163=establishment or maintenance of cell polarity" "0008021=synaptic vesicle, 0031594=neuromuscular junction, 0016021=integral component of membrane" "Tomosyn, CG17762, CG11056, BcDNA:RH19475, tomosyn, CG2205" "IPR001388=Synaptobrevin, IPR001680=WD40 repeat, IPR000664=Lethal(2) giant larvae protein, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR013577=Lethal giant larvae homologue 2" CG17762 16-Dec-15 2015_12 "ENSDARG00000029234(stxbp5b),ENSDARG00000002656(stxbp5a),ENSDARG00000006383(si:ch211-194d6.1)" "YPR032W(SRO7),YBL106C(SRO77)" WBGene00006594(tom-1) "ENSMUSG00000019790(Stxbp5),ENSMUSG00000022829(Stxbp5l)" "ENSG00000164506(STXBP5),ENSG00000145087(STXBP5L)" "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,neurophysiology defective,memory defective" "embryonic/larval hemocyte | third instar larval stage,embryonic/larval neuroblast,ganglion mother cell,intersegmental nerve,anterior fascicle & synapse" FBgn0083021 snoRNA:ë¬18S-640f snoRNA:ë¬18S-640f http://flybase.net/reports/FBgn0083021.html snoRNA_gene "CR34583, psi18s-640f" CR34583 16-Dec-15 2015_12 FBgn0267671 CR46007 http://flybase.net/reports/FBgn0267671.html non_protein_coding_gene CR46007 16-Dec-15 2015_12 FBgn0008652 mei-S82 meiotic from via Salaria 82 http://flybase.net/reports/FBgn0008652.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "female sterile,meiotic cell cycle defective,female" FBgn0040088 p110 p110 http://flybase.net/reports/FBgn0040088.html gene 16-Dec-15 2015_12 FBgn0266998 ë±-Cat::baz http://flybase.net/reports/FBgn0266998.html engineered_fusion_gene Baz::alphaCat 16-Dec-15 2015_12 FBgn0000894 fs(1)M94 female sterile (1) M94 http://flybase.net/reports/FBgn0000894.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0026303 anon-16Ff anon-16Ff http://flybase.net/reports/FBgn0026303.html gene HL-VII 16-Dec-15 2015_12 FBgn0004192 snRNA:U2:34ABb small nuclear RNA U2 at 34ABb http://flybase.net/reports/FBgn0004192.html "FBgn0003919, FBgn0003921, FBgn0051854" snRNA_gene "0000398=mRNA splicing, via spliceosome" "0015030=Cajal body, 0005686=U2 snRNP" "Dm U2-131B, U2 snRNA, 131B, U2-131B, K6, 34B U2, CR31854, dU2, D.U2-2, U2 131B, U2, snRNA-U2-131B, U2-34ABb, small nuclear RNA U2, snRNA:U2, U2snRNA, U2:34ABb, U2-69E5, U2snRNA34ABb" CR31854 16-Dec-15 2015_12 FBgn0067783 att-ORFA alternative testis transcripts open reading frame A http://flybase.net/reports/FBgn0067783.html "FBgn0019839, FBgn0038801" protein_coding_gene 0022857=transmembrane transporter activity "0055085=transmembrane transport, 0050829=defense response to Gram-negative bacterium, 0006839=mitochondrial transport, 0045089=positive regulation of innate immune response" "0031966=mitochondrial membrane, 0016021=integral component of membrane, 0005743=mitochondrial inner membrane, 0005740=mitochondrial envelope" "CG4241, att, unnamed, alternative testis transcripts" "IPR002067=Mitochondrial carrier protein, IPR002167=Graves disease carrier protein, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG4241 16-Dec-15 2015_12 ENSDARG00000003470(slc25a42) YHR002W(LEU5) WBGene00009666(F43G9.3) ENSXETG00000014336(SLC25A42) ENSMUSG00000002346(Slc25a42) ENSG00000181035(SLC25A42) FBgn0265167 CR44236 http://flybase.net/reports/FBgn0265167.html non_protein_coding_gene CR44236 16-Dec-15 2015_12 FBgn0046632 anon-38E.4 anon-38E.4 http://flybase.net/reports/FBgn0046632.html gene 38E.4 16-Dec-15 2015_12 FBgn0060480 l(3)S111001 lethal (3) S111001 http://flybase.net/reports/FBgn0060480.html gene 1110/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033486 dmpd dampened http://flybase.net/reports/FBgn0033486.html protein_coding_gene "0003713=transcription coactivator activity, 0004842=ubiquitin-protein transferase activity" "0045893=positive regulation of transcription, DNA-templated, 0009952=anterior/posterior pattern specification, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" "0019005=SCF ubiquitin ligase complex, 0005634=nucleus" "FBXO13, CG11866" IPR001810=F-box domain CG11866 16-Dec-15 2015_12 "viable,fertile" FBgn0035838 ldbr lariat debranching enzyme http://flybase.net/reports/FBgn0035838.html protein_coding_gene 0008419=RNA lariat debranching enzyme activity "0000375=RNA splicing, via transesterification reactions, 0006397=mRNA processing, 0006396=RNA processing" 0005634=nucleus "lariat-debranching enzyme, CG7942, Lbdr, Ldbr" "IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR007708=Lariat debranching enzyme, C-terminal" CG7942 16-Dec-15 2015_12 ENSDARG00000056923(dbr1) YKL149C(DBR1) WBGene00000937(dbr-1) ENSXETG00000027491(Q6P886_XENTR) ENSMUSG00000032469(Dbr1) ENSG00000138231(DBR1) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016830 l(1)MZ17 lethal (1) MZ17 http://flybase.net/reports/FBgn0016830.html gene M17 16-Dec-15 2015_12 "lethal,recessive" FBgn0000164 bb bobbed http://flybase.net/reports/FBgn0000164.html "FBgn0003454, FBgn0010322, FBgn0014124, FBgn0014125, FBgn0025282" rRNA_gene "0022627=cytosolic small ribosomal subunit, 0022625=cytosolic large ribosomal subunit" "small nuclear RNA a, ITS1, unnamed, rRNA, rDNA unit, ribosomal RNA, Xbb, anon-EST:Liang-1.69, snRNA-a, NO, rDNA repeat, 35S rRNA, flex, female-specific lethal on X, rDNA, anon-EST:Posey92, clone 1.69, l(1)20Fa" 16-Dec-15 2015_12 "lethal,recessive,visible,viable,heat sensitive,female,wild-type,male,dominant,female fertile,poor" "macrochaeta,tergite,male genitalia,abdominal segment,ovary,germline clone,egg chamber,abdomen" FBgn0061117 l(3)S005310 lethal (3) S005310 http://flybase.net/reports/FBgn0061117.html gene 0053/10 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0067628 CG33331 http://flybase.net/reports/FBgn0067628.html "FBgn0038270, FBgn0053331, FBgn0069055" protein_coding_gene 0004605=phosphatidate cytidylyltransferase activity 0032049=cardiolipin biosynthetic process 0031314=extrinsic component of mitochondrial inner membrane "CG3641, BcDNA:SD17447" IPR015222=Mitochondrial matrix Mmp37 CG33331 16-Dec-15 2015_12 YGR046W(TAM41) WBGene00022126(Y71F9B.2) ENSXETG00000015634(C3orf31) ENSMUSG00000030316(1500001M20Rik) ENSG00000144559(TAMM41) DRSC29492 K 0.110647636 0.360996953 -0.141687394 -0.217891704 1.534495509 -0.146234172 FBgn0027381 Idefix\gag gag http://flybase.net/reports/FBgn0027381.html transposable_element_gene "ORF1, gag" 16-Dec-15 2015_12 FBgn0033459 CG12744 http://flybase.net/reports/FBgn0033459.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0050832=defense response to fungus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG12744 16-Dec-15 2015_12 ENSMUSG00000016503(Gtf3a) "immune response defective,viable,fertile" "hemocyte,crystal cell" FBgn0264876 CR44067 http://flybase.net/reports/FBgn0264876.html non_protein_coding_gene CR44067 16-Dec-15 2015_12 FBgn0259106 dar8 dendritic arbor reduction 8 http://flybase.net/reports/FBgn0259106.html gene 0050775=positive regulation of dendrite morphogenesis 16-Dec-15 2015_12 FBgn0069933 CG41118 http://flybase.net/reports/FBgn0069933.html FBan0041118 protein_coding_gene 16-Dec-15 2015_12 FBgn0263407 CR43453 http://flybase.net/reports/FBgn0263407.html non_protein_coding_gene CR43453 16-Dec-15 2015_12 FBgn0060504 l(3)S105407 lethal (3) S105407 http://flybase.net/reports/FBgn0060504.html gene 1054/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0016649 Frda Frda http://flybase.net/reports/FBgn0016649.html gene Frd 16-Dec-15 2015_12 visible eye FBgn0002286 l(3)73Bb lethal (3) 73Bb http://flybase.net/reports/FBgn0002286.html gene "l(3)std10, l(3L)73Bb" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266098 rg rugose http://flybase.net/reports/FBgn0266098.html "FBgn0086911, FBgn0003244, FBgn0021748, FBgn0040912, FBgn0029748" protein_coding_gene 0051018=protein kinase A binding "0007528=neuromuscular junction development, 0007614=short-term memory, 0008355=olfactory learning, 0016319=mushroom body development, 0042675=compound eye cone cell differentiation, 0008104=protein localization" "0005737=cytoplasm, 0016021=integral component of membrane, 0043025=neuronal cell body" "CG6775, fas, Drosophila A kinase anchor protein, DAKAP550, CG15465/CG6775, pebbled, CG15466, A kinase anchor protein 550, CG15464, facetious, AKAP, CG44835, A-kinase anchoring protein, Akap550" "IPR010508=Domain of unknown function DUF1088, IPR023362=PH-BEACH domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR016024=Armadillo-type fold, IPR001680=WD40 repeat, IPR000409=BEACH domain" CG44835 16-Dec-15 2015_12 WBGene00004760(sel-2) "ENSMUSG00000027799,ENSMUSG00000028080(Lrba)" "ENSG00000172915(NBEA),ENSG00000198589(LRBA)" DRSC18049 EK -0.395888772 0.823397946 1.54694462 0.290017571 2.363878037 0.66322466 FBgn0016966 vm3 visible mutation-3 http://flybase.net/reports/FBgn0016966.html gene 16-Dec-15 2015_12 visible wing FBgn0060779 l(3)S060708 lethal (3) S060708 http://flybase.net/reports/FBgn0060779.html gene 0607/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0023041 l(2)46Eb lethal (2) 46Eb http://flybase.net/reports/FBgn0023041.html "FBgn0019707, FBgn0019727" gene "28.19, unnamed, Complementation group A, 1.2, l(2)46CFa, A complementation group, l(2)46CFu, A" 16-Dec-15 2015_12 lethal FBgn0002863 Acp95EF Accessory gland protein 95EF http://flybase.net/reports/FBgn0002863.html FBgn0039171 protein_coding_gene 0032504=multicellular organism reproduction "0005615=extracellular space, 0005576=extracellular region" "Acp, mst 316, CG17924, Mst95E, mst(3)ag-3, DTA-D, mst316, DTA-E, mst316F, Accessory gland-specific peptide 95EF, Mst95F, mst-3" CG17924 16-Dec-15 2015_12 viable DRSC15857 I -2.090497657 0.906310634 0.063299046 -0.804405998 0.393053774 -0.30832586 FBgn0000697 fltC flight defective C http://flybase.net/reports/FBgn0000697.html gene 16-Dec-15 2015_12 "flightless,heat sensitive" FBgn0039602 CG1647 http://flybase.net/reports/FBgn0039602.html protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" "0006351=transcription, DNA-templated" 0005634=nucleus "IPR027775=C2H2- zinc finger protein family, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like, IPR002068=Alpha crystallin/Hsp20 domain, IPR007087=Zinc finger, C2H2" CG1647 16-Dec-15 2015_12 "viable,fertile" FBgn0037757 CG8516 http://flybase.net/reports/FBgn0037757.html protein_coding_gene FBgn0037757 CG8516 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050125 Ir56a Ionotropic receptor 56a http://flybase.net/reports/FBgn0050125.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG30125, DmelIR56a, IR56a, ionotropic receptor 56a" CG30125 16-Dec-15 2015_12 viable FBgn0031329 CG14344 http://flybase.net/reports/FBgn0031329.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001941 ifc infertile crescent http://flybase.net/reports/FBgn0001941.html protein_coding_gene "0042284=sphingolipid delta-4 desaturase activity, 0004768=stearoyl-CoA 9-desaturase activity" "0030148=sphingolipid biosynthetic process, 0007283=spermatogenesis, 0007053=spindle assembly involved in male meiosis" "0016006=Nebenkern, 0070938=contractile ring, 0005739=mitochondrion, 0016021=integral component of membrane, 0005886=plasma membrane" "Ifc, ms(2)04875, degenerative spermatocyte, sphingolipid delta 4 desaturase, l(2)26Ab, Infertile crescent, CG9078, Des1, des, des1, degenerating spermatocyte, DES-1, l(2)gdh-2, des-1" "IPR011388=Sphingolipid delta4-desaturase, IPR005804=Fatty acid desaturase domain, IPR013866=Sphingolipid delta4-desaturase, N-terminal" CG9078 16-Dec-15 2015_12 "ENSDARG00000042544(degs2),ENSDARG00000007347(degs1)" WBGene00013197(Y54E5A.1) "ENSXETG00000018586(TGas057c03.1),ENSXETG00000012858(TNeu066d19.1),ENSXETG00000002528()" "ENSMUSG00000038633(Degs1),ENSMUSG00000038768(9130409I23Rik),ENSMUSG00000021263(Degs2)" "ENSG00000143753(DEGS1),ENSG00000168350(DEGS2)" spermatogenesis && adult stage " spermatocyte

, testis

" adult stage | male " spermatid

, Nebenkern

, spermatocyte

" "male sterile,recessive,partially lethal - majority die,some die during embryonic stage,cytokinesis defective,male,lethal,lethal - all die before end of embryonic stage,some die during pupal stage" "testis,spermatocyte,spermatid,spermatid & nucleus,spindle,aster,meiotic cell cycle" FBgn0023024 l(3)82Ca lethal (3) 82Ca http://flybase.net/reports/FBgn0023024.html gene unnamed 16-Dec-15 2015_12 FBgn0011193 l(1)302-1 lethal (1) 302-1 http://flybase.net/reports/FBgn0011193.html FBgn0010202 gene 302-1 16-Dec-15 2015_12 "lethal,recessive" FBgn0031711 CG6907 http://flybase.net/reports/FBgn0031711.html protein_coding_gene 0008607=phosphorylase kinase regulator activity 0006357=regulation of transcription from RNA polymerase II promoter "0033588=Elongator holoenzyme complex, 0005737=cytoplasm, 0008023=transcription elongation factor complex" "IPR008728=Elongator complex protein 4, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6907 16-Dec-15 2015_12 ENSDARG00000008852(elp4) ENSXETG00000008176(ELP4) ENSMUSG00000027167(Elp4) ENSG00000109911(ELP4) "viable,fertile" DRSC02999 IE 0.636640764 -5.667336989 -1.369778518 -3.819421583 -1.255729381 0.938592083 FBgn0063395 Stalker2\ORF4 ORF4 http://flybase.net/reports/FBgn0063395.html transposable_element_gene rom\ORF4 16-Dec-15 2015_12 FBgn0265451 CR44351 http://flybase.net/reports/FBgn0265451.html non_protein_coding_gene CR44351 16-Dec-15 2015_12 FBgn0266677 CR45167 http://flybase.net/reports/FBgn0266677.html non_protein_coding_gene CR45167 16-Dec-15 2015_12 FBgn0058091 CG40091 http://flybase.net/reports/FBgn0058091.html FBan0040091 protein_coding_gene 16-Dec-15 2015_12 FBgn0026209 limo limo http://flybase.net/reports/FBgn0026209.html gene 0016055=Wnt signaling pathway 16-Dec-15 2015_12 "lethal,recessive" FBgn0002725 macrofine macrofine http://flybase.net/reports/FBgn0002725.html gene mf 16-Dec-15 2015_12 "visible,recessive,viable,male,female,reduced,male fertile" macrochaeta FBgn0013669 ms(3)neo5 ms(3)neo5 http://flybase.net/reports/FBgn0013669.html gene unnamed 16-Dec-15 2015_12 "male sterile,male semi-sterile,recessive" FBgn0001491 l(1)10Bb lethal (1) 10Bb http://flybase.net/reports/FBgn0001491.html FBgn0027286 protein_coding_gene 0005515=protein binding "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0071011=precatalytic spliceosome" "l(1)GLM14, 10Ba, L(1)10Bb, l(1)G14, CG1639, l(1)G0169, lethal(1)10Bb" "IPR001748=G10 protein, IPR018230=BUD31/G10-related, conserved site" CG1639 16-Dec-15 2015_12 ENSDARG00000017084(bud31) YCR063W(BUD31) WBGene00007400(C07A9.2) ENSXETG00000024872(BUD31) ENSMUSG00000038722(Bud31) ENSG00000106245(BUD31) "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0086447 l(2)37Cg lethal (2) 37Cg http://flybase.net/reports/FBgn0086447.html "FBgn0002035, FBgn0032762" protein_coding_gene "0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity, 0046983=protein dimerization activity" 0006360=transcription from RNA polymerase I promoter "0005666=DNA-directed RNA polymerase III complex, 0005736=DNA-directed RNA polymerase I complex, 0005875=microtubule associated complex" "Cg, CG10685" "IPR009025=DNA-directed RNA polymerase, RBP11-like dimerisation domain, IPR008193=DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site" CG10685 16-Dec-15 2015_12 ENSDARG00000037570(zgc:136449) ENSXETG00000024795(POLR1D) ENSMUSG00000029642(Polr1d) FBgn0027118 mei-P14 mei-P14 http://flybase.net/reports/FBgn0027118.html gene 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0267949 CR46229 http://flybase.net/reports/FBgn0267949.html non_protein_coding_gene lincRNA.280 CR46229 16-Dec-15 2015_12 FBgn0000038 nAChRë_1 nicotinic Acetylcholine Receptor ë_1 http://flybase.net/reports/FBgn0000038.html protein_coding_gene 0004889=acetylcholine-activated cation-selective channel activity "0006811=ion transport, 0007271=synaptic transmission, cholinergic" "0005887=integral component of plasma membrane, 0045211=postsynaptic membrane, 0005892=acetylcholine-gated channel complex" "CG11348, nAChR, CG11348-PA, AcrD, AChR protein of Drosophila, nAcRbeta-64B, AChR, AchR64B, beta 64B, nicotinic Acetylcholine Receptor beta 64B, Dbeta1, ARD, Acr64B, ard, Ard, CG12606, AChR64B, nAcR64B, nicotinic acetylcholine receptorb-64B" "IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR002394=Nicotinic acetylcholine receptor, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site" CG11348 16-Dec-15 2015_12 "WBGene00006765(unc-29),WBGene00002974(lev-1),WBGene00000043(acr-3),WBGene00000042(acr-2)" " larval stage | second instar , embryonic stage -- adult stage , embryonic stage | stage 13-17 , adult stage , pupal stage && adult stage , embryonic stage | mid-late , pupal stage&&adult stage " " ventral nerve cord

, central nervous system

, cell

, supraesophageal ganglion

, medulla cortex

, lamina

, lamina cortex

, lobula plate cortex

, larval brain

, subesophageal ganglion

, embryonic central nervous system | presumptive

, medulla

" "viable,partially lethal - majority die,some die during pupal stage" FBgn0067747 l(1)G0243 lethal (1) G0243 http://flybase.net/reports/FBgn0067747.html gene 16-Dec-15 2015_12 lethal FBgn0040963 CG18662 http://flybase.net/reports/FBgn0040963.html protein_coding_gene IPR007702=Janus CG18662 16-Dec-15 2015_12 viable FBgn0060608 l(3)S090411b lethal (3) S090411b http://flybase.net/reports/FBgn0060608.html gene 0904/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0086054 snoRNA:Me18S-G1358b http://flybase.net/reports/FBgn0086054.html snoRNA_gene "Me18S-Gm1358b, CR34683" CR34683 16-Dec-15 2015_12 FBgn0263029 CG43324 http://flybase.net/reports/FBgn0263029.html "FBgn0034241, FBan0015844, FBgn0004377" protein_coding_gene 0004871=signal transducer activity 0007186=G-protein coupled receptor signaling pathway 0005834=heterotrimeric G-protein complex CG15844 "IPR015898=G-protein gamma-like domain, IPR001770=G-protein, gamma subunit" CG43324 16-Dec-15 2015_12 "lethal,recessive" FBgn0025136 su(RpII140Z36)S11 su(RpII140Z36)S11 http://flybase.net/reports/FBgn0025136.html gene Z36[S11] 16-Dec-15 2015_12 FBgn0032016 CG7818 http://flybase.net/reports/FBgn0032016.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0016422=mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity" 0001510=RNA methylation 0005634=nucleus "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR007757=MT-A70-like" CG7818 16-Dec-15 2015_12 ENSDARG00000070278(mettl14) YCL055W(KAR4) ENSXETG00000004037(BC080361.2) ENSMUSG00000028114(Mettl14) ENSG00000145388(METTL14) "viable,fertile,visible" mesothoracic tergum FBgn0028840 BG:DS09219.1 BG:DS09219.1 http://flybase.net/reports/FBgn0028840.html gene DS09219.1 16-Dec-15 2015_12 FBgn0024645 l(2)k09931 lethal (2) k09931 http://flybase.net/reports/FBgn0024645.html gene 99/31 16-Dec-15 2015_12 "visible,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal" "imaginal disc,wing,wing vein" FBgn0023517 Pgam5 Phosphoglycerate mutase 5 http://flybase.net/reports/FBgn0023517.html protein_coding_gene "0005515=protein binding, 0004722=protein serine/threonine phosphatase activity, 0043539=protein serine/threonine kinase activator activity, 0004619=phosphoglycerate mutase activity" "0072347=response to anesthetic, 0010821=regulation of mitochondrion organization, 0009408=response to heat, 0035970=peptidyl-threonine dephosphorylation, 0090141=positive regulation of mitochondrial fission" "0005739=mitochondrion, 0016021=integral component of membrane" "dPGAM5, PGAM5, EG:63B12.4, CG14816, DPGAM5" "IPR029033=Histidine phosphatase superfamily, IPR013078=Histidine phosphatase superfamily, clade-1" CG14816 16-Dec-15 2015_12 ENSDARG00000035608(pgam5) WBGene00019941(pgam-5) ENSXETG00000023845(TEgg128n03.1) ENSMUSG00000029500(Pgam5) ENSG00000176894(PXMP2) "heat stress response defective,viable,fertile,long lived,locomotor behavior defective,decreased cell number,short lived,chemical sensitive,recessive" "mitochondrion,adult mushroom body,Kenyon cell,mitochondrionda.G32,embryonic/larval hemocyte | third instar larval stage" FBgn0260953 CG42585 http://flybase.net/reports/FBgn0260953.html protein_coding_gene 0008270=zinc ion binding "IPR008598=Drought induced 19 protein type, zinc-binding domain, IPR000433=Zinc finger, ZZ-type, IPR015880=Zinc finger, C2H2-like" CG42585 16-Dec-15 2015_12 FBgn0040557 CG14364 http://flybase.net/reports/FBgn0040557.html protein_coding_gene 16-Dec-15 2015_12 FBgn0015552 teg tegamino http://flybase.net/reports/FBgn0015552.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile,recessive" "egg chamber,nurse cell" FBgn0026375 RhoGAPp190 Rho GTPase activating protein p190 http://flybase.net/reports/FBgn0026375.html "FBgn0030856, FBgn0030857, FBgn0046792, FBgn0052555, FBgn0062491" protein_coding_gene "0005096=GTPase activator activity, 0005525=GTP binding, 0030215=semaphorin receptor binding" "0007415=defasciculation of motor neuron axon, 0045792=negative regulation of cell size, 0050770=regulation of axonogenesis, 0016319=mushroom body development, 0007266=Rho protein signal transduction" "Rp190RhoGAP, RhoGAP P190, RhoGAP, DRhoGAP, p190 RhoGAP, D-p190, CG32555, p190-RhoGAP, CG8240, p190, RhoGAP-16B12, CG8267, BcDNA:GH17919, 8267, RhoGAPp190, mdcds_56566, p190RhoGAP, BcDNA:GM05133" "IPR000198=Rho GTPase-activating protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR008936=Rho GTPase activation protein, IPR002713=FF domain" CG32555 16-Dec-15 2015_12 "ENSDARG00000061294(arhgap5),ENSDARG00000062577(LOC100004299),ENSDARG00000060297(LOC100334223)" WBGene00010374(rga-5) "ENSXETG00000018284(GRLF1),ENSXETG00000014123(ARHGAP5)" "ENSMUSG00000058230(Grlf1),ENSMUSG00000035133(Arhgap5)" "ENSG00000160007(ARHGAP35),ENSG00000100852(ARHGAP5)" "neuroanatomy defective,viable,fertile,lethal,body color defective" "intersegmental nerve branch ISNb of A1-7,medial lobe & axoney-OK107,mushroom body beta-lobe,vertical lobe of adult mushroom body,adult mushroom body,wing hair,supernumerary,mesothoracic tergum" FBgn0261925 CG42792 http://flybase.net/reports/FBgn0261925.html protein_coding_gene HDC02744 CG42792 16-Dec-15 2015_12 FBgn0031074 SkpE SKP1-related E http://flybase.net/reports/FBgn0031074.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0022008=neurogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "SkpE, CG11942, Skp, skpE" "IPR016073=SKP1 component, POZ domain, IPR001232=S-phase kinase-associated protein 1-like, IPR016072=SKP1 component, dimerisation, IPR011333=POZ domain, IPR016897=S-phase kinase-associated protein 1" CG11942 16-Dec-15 2015_12 "viable,visible,body color defective,lethal,neuroanatomy defective" "chaeta,supernumerary,mesothoracic tergum,ganglion mother cell" FBgn0028005 l(3)S116415 lethal (3) S116415 http://flybase.net/reports/FBgn0028005.html gene 1164/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011336 OstStt3 Oligosaccharyl transferase 3 http://flybase.net/reports/FBgn0011336.html FBgn0027069 protein_coding_gene 0004576=oligosaccharyl transferase activity 0006486=protein glycosylation "0008250=oligosaccharyltransferase complex, 0012505=endomembrane system" "STT, anon-WO03054008.7, BcDNA.GM01838, BcDNA:GM01838, CG7748, l(3)j2D9" "IPR003674=Oligosaccharyl transferase, STT3 subunit" CG7748 16-Dec-15 2015_12 ENSDARG00000001890(stt3b) YGL022W(STT3) WBGene00020437(T12A2.2) ENSMUSG00000032437(Stt3b) ENSG00000163527(STT3B) "lethal,recessive" FBgn0002550 lgt leg tumor http://flybase.net/reports/FBgn0002550.html gene 16-Dec-15 2015_12 "visible,sterile,viable,poor,melanotic mass phenotype" melanotic mass FBgn0263603 Zn72D Zinc-finger protein at 72D http://flybase.net/reports/FBgn0263603.html "FBgn0017453, FBgn0005543" protein_coding_gene "0008270=zinc ion binding, 0003729=mRNA binding" "0006909=phagocytosis, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "CG5215, lethal (3) 72Dk, zn72D, Zn72D, l(3)72Dk, ZN72D" "IPR006561=DZF domain, IPR015880=Zinc finger, C2H2-like, IPR003604=Zinc finger, U1-type, IPR007087=Zinc finger, C2H2" CG5215 16-Dec-15 2015_12 "ENSDARG00000071683(LOC567465),ENSDARG00000027109(zfr)" WBGene00022387(Y95B8A.7) ENSXETG00000015598(zfr) "ENSMUSG00000034949,ENSMUSG00000022201(Zfr)" "ENSG00000105278(ZFR2),ENSG00000056097(ZFR)" FBgn0028746 CG18508 http://flybase.net/reports/FBgn0028746.html "FBgn0041573, FBgn0042220" protein_coding_gene "CG4015, EG:140G11.3" IPR026776=Uncharacterised protein family UPF0729 CG18508 16-Dec-15 2015_12 FBgn0028969 ë«COP Coat Protein (coatomer) ë« http://flybase.net/reports/FBgn0028969.html "FBgn0015013, FBgn0020026, FBgn0026700, FBgn0027227, FBgn0029593, FBgn0040159, FBgn0066816" protein_coding_gene "0010883=regulation of lipid storage, 0009306=protein secretion, 0006909=phagocytosis, 0035158=regulation of tube diameter, open tracheal system, 0007436=larval salivary gland morphogenesis, 0006890=retrograde vesicle-mediated transport, Golgi to ER" 0030126=COPI vesicle coat "l(1)G0051, deltaCOP, deltaCop, l(1)G0450, delta-Cop, ARCN1, Delta COP, COPI delta subunit, DM63B12S, CG14813, EG:63B12.10, DeltaCop, ESTS:63B12S, 63B12S, coatomer complex COPI delta-COP subunit, Arch, l(1)G0301, anon-WO03040301.246, Archain, delta-coatomer protein" "IPR011012=Longin-like domain, IPR028565=Mu homology domain, IPR027059=Coatomer delta subunit, IPR022775=AP complex, mu/sigma subunit" CG14813 16-Dec-15 2015_12 "ENSDARG00000031214(arcn1l),ENSDARG00000002792(arcn1)" YFR051C(RET2) WBGene00015734(C13B9.3) "ENSXETG00000021568(arcn1),ENSXETG00000016544()" ENSMUSG00000032096(Arcn1) ENSG00000095139(ARCN1) embryonic stage -- adult stage "visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,male,female" "wing,embryonic/larval dorsal trunk,embryonic/larval salivary gland" DRSC25961 IEK 0.180539541 1.688872606 1.303964135 -2.911616603 -0.314261504 -1.567055115 FBgn0036639 CG4229 http://flybase.net/reports/FBgn0036639.html protein_coding_gene IPR004011=GYR motif CG4229 16-Dec-15 2015_12 viable FBgn0002987 Off Off http://flybase.net/reports/FBgn0002987.html gene 16-Dec-15 2015_12 visible "macrochaeta,eye" FBgn0034278 CG14488 http://flybase.net/reports/FBgn0034278.html protein_coding_gene CG14488 16-Dec-15 2015_12 viable DRSC06460 I -2.160215434 0.258909593 0.203609301 0.588963354 1.351300754 0.334573812 FBgn0023035 l(2)46Eh lethal (2) 46Eh http://flybase.net/reports/FBgn0023035.html FBgn0019706 gene "Complementation group R, R, l(2)46CFv, 29.26, unnamed" 16-Dec-15 2015_12 lethal FBgn0000123 Ars-region1 Autonomous replicating sequence region 1 http://flybase.net/reports/FBgn0000123.html region "Ars sequence 1, PHa640, Ars1" 16-Dec-15 2015_12 FBgn0033602 Cpr47Ee Cuticular protein 47Ee http://flybase.net/reports/FBgn0033602.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr47Ee, CG13222" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG13222 16-Dec-15 2015_12 DRSC23164 K -0.400088614 -1.783018957 FBgn0051227 CG31227 http://flybase.net/reports/FBgn0051227.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083287 E(smoDN)2101 Enhancer of smoDN 2101 http://flybase.net/reports/FBgn0083287.html gene 16-Dec-15 2015_12 FBgn0035001 Slik Sterile20-like kinase http://flybase.net/reports/FBgn0035001.html protein_coding_gene "0005524=ATP binding, 0042801=polo kinase kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" "0007091=metaphase/anaphase transition of mitotic cell cycle, 0000902=cell morphogenesis, 0000132=establishment of mitotic spindle orientation, 0032879=regulation of localization, 0033109=cortical actin cytoskeleton stabilization, 0007052=mitotic spindle organization, 0008283=cell proliferation, 0010800=positive regulation of peptidyl-threonine phosphorylation, 0000281=mitotic cytokinesis, 0006468=protein phosphorylation" "0005938=cell cortex, 0032154=cleavage furrow, 1990023=mitotic spindle midzone" "slk, dPlkk, Polo kinase kinase 1, PLKK1, dPlkk/Slik threonine kinase, Slk, dPlkk/Slik, SLIK, CG4527, Sterile-20, slik, SLK, Plkk1, Ste20 kinase, DPlkk1, Slik1, Plkk/Slik, polo kinase kinase 1, Slik" "IPR017441=Protein kinase, ATP binding site, IPR022165=Polo kinase kinase, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG4527 16-Dec-15 2015_12 "ENSDARG00000012574,ENSDARG00000061525(slkn)" WBGene00007287(gck-4) ENSXETG00000014423(STK10) ENSMUSG00000025060(Slk) ENSG00000072786(STK10) "increased cell death,somatic clone,partially lethal - majority die,small body,developmental rate defective,recessive,lethal - all die before end of larval stage,partially,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,mitotic cell cycle defective,cell non-autonomous,viable" "wing,somatic clone,wing & epithelial cell,wing & epithelial cell | ectopic,rhabdomere,ommatidium & microvillus | somatic clone,1st posterior cell,peripodial epithelium" FBgn0037078 CG12971 http://flybase.net/reports/FBgn0037078.html protein_coding_gene CG12971 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0005443 l(1)v146 lethal (1) v146 http://flybase.net/reports/FBgn0005443.html gene l(1)146 16-Dec-15 2015_12 FBgn0016663 Hrp39 Hrp39 http://flybase.net/reports/FBgn0016663.html gene 0003697=single-stranded DNA binding hrp39 16-Dec-15 2015_12 FBgn0082967 snoRNA:ë¬28S-3327a snoRNA:ë¬28S-3327a http://flybase.net/reports/FBgn0082967.html snoRNA_gene "Psi 28S-3327a, chr3L:13016676..13016828, Psi28S-3327a, pug28S-3327, psi28S-3327a, CR34642" CR34642 16-Dec-15 2015_12 FBgn0000485 dow downy http://flybase.net/reports/FBgn0000485.html gene 16-Dec-15 2015_12 "viable,visible,male sterile" "Nebenkern,spermatid,spermatocyte & nucleus,macrochaeta" FBgn0266639 CR45146 http://flybase.net/reports/FBgn0266639.html non_protein_coding_gene CR45146 16-Dec-15 2015_12 FBgn0023454 Cad47B Cad47B http://flybase.net/reports/FBgn0023454.html gene "0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0007413=axonal fasciculation" 0016021=integral component of membrane "Cad49, cad47B" 16-Dec-15 2015_12 FBgn0028002 l(3)S119608 lethal (3) S119608 http://flybase.net/reports/FBgn0028002.html gene 1196/08 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0064244 ELK1 ELK1 http://flybase.net/reports/FBgn0064244.html gene ELK-1 16-Dec-15 2015_12 FBgn0069930 CG41121 http://flybase.net/reports/FBgn0069930.html FBan0041121 protein_coding_gene 16-Dec-15 2015_12 FBgn0031365 CG17650 http://flybase.net/reports/FBgn0031365.html protein_coding_gene CG17650 16-Dec-15 2015_12 viable DRSC00510 E 0.959538892 -0.062342568 1.74378216 5.190413662 -0.565726668 -0.108142915 FBgn0085671 CG41529 http://flybase.net/reports/FBgn0085671.html FBan0041529 protein_coding_gene 16-Dec-15 2015_12 FBgn0039200 CG13616 http://flybase.net/reports/FBgn0039200.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG13616 16-Dec-15 2015_12 viable FBgn0065749 l(2)SH0499 lethal (2) SH0499 http://flybase.net/reports/FBgn0065749.html gene l(2)SH2 0499 16-Dec-15 2015_12 "lethal,recessive" FBgn0262581 CG43121 http://flybase.net/reports/FBgn0262581.html protein_coding_gene CG43121 16-Dec-15 2015_12 FBgn0004185 snRNA:U1:95Ca small nuclear RNA U1 at 95Ca http://flybase.net/reports/FBgn0004185.html "FBgn0003915, FBgn0003918, FBgn0026851, FBgn0051341" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005685=U1 snRNP "CR31341, K5, U1a-95Ca, small nuclear RNA U1, snRNA-U1-95.1, u1a, U1-95Ca, U1, 95C U1, U1snRNA95Ca, DMU1951, snRNA:U1, U1a, U1snRNA, U1:95Ca, U1 snRNA, U1snRNA 95.1, U1-95.1, U1:95C, U1951" CR31341 16-Dec-15 2015_12 FBgn0003423 slgA sluggish A http://flybase.net/reports/FBgn0003423.html protein_coding_gene "0004657=proline dehydrogenase activity, 0071949=FAD binding" "0006562=proline catabolic process, 0006537=glutamate biosynthetic process, 0042331=phototaxis, 0007626=locomotory behavior" "0005739=mitochondrion, 0005759=mitochondrial matrix" "sluggish-A, slg, CG1417, sl, sluggish, PRODH, tu3, proline dehydrogenase, EE85, sluggishA" "IPR029041=FAD-linked oxidoreductase-like, IPR015659=Proline oxidase, IPR002872=Proline dehydrogenase domain" CG1417 16-Dec-15 2015_12 ENSDARG00000021154(zgc:92040) WBGene00007197(B0513.5) ENSXETG00000021664(PRODH) ENSMUSG00000003526(Prodh) ENSG00000100033(PRODH) embryonic stage " anal pad

, embryonic central nervous system

" "uncoordinated,hypoactive,recessive,locomotor behavior defective,behavior defective,wild-type,viable" FBgn0017431 anon-4Bc anon-4Bc http://flybase.net/reports/FBgn0017431.html gene Gene D 16-Dec-15 2015_12 FBgn0267634 CR45972 http://flybase.net/reports/FBgn0267634.html non_protein_coding_gene Dm_3L:111571 CR45972 16-Dec-15 2015_12 FBgn0036340 SRm160 SRm160 http://flybase.net/reports/FBgn0036340.html protein_coding_gene "0048806=genitalia development, 0000398=mRNA splicing, via spliceosome, 0048749=compound eye development, 0043068=positive regulation of programmed cell death, 0006397=mRNA processing, 0018993=somatic sex determination" "0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0035145=exon-exon junction complex, 0071011=precatalytic spliceosome" "CG11274, SRM160" IPR002483=PWI domain CG11274 16-Dec-15 2015_12 ENSDARG00000001244(srrm1) WBGene00004706(rsr-1) ENSMUSG00000028809(Srrm1)

"viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0033953 CG12861 http://flybase.net/reports/FBgn0033953.html protein_coding_gene "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG12861 16-Dec-15 2015_12 FBgn0025175 l(2)38Da lethal (2) 38Da http://flybase.net/reports/FBgn0025175.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264618 CR43958 http://flybase.net/reports/FBgn0264618.html non_protein_coding_gene CR43958 16-Dec-15 2015_12 FBgn0266585 tRNA:CR32456 transfer RNA:CR32456 http://flybase.net/reports/FBgn0266585.html "FBgn0052456, FBgn0060155, FBgn0011908" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033420=CUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:leu2:79F, tRNA[LEU], tRNA:L2:79F, tRNA:L:CAG:AE002647, transfer RNA:leu2:79F, CR32456, tRNA[Leu], AE002647.trna1-LeuCAG, chr3L.trna32-LeuCAG, tRNA[Leu][[2]]" CR32456 16-Dec-15 2015_12 FBgn0035444 CG12012 http://flybase.net/reports/FBgn0035444.html protein_coding_gene IPR019317=Brain protein I3 CG12012 16-Dec-15 2015_12 ENSXETG00000024037(BRI3) ENSMUSG00000047843(Bri3) ENSG00000164713(BRI3) viable FBgn0013546 l(2)M11 lethal (2) M11 http://flybase.net/reports/FBgn0013546.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259953 CG42463 http://flybase.net/reports/FBgn0259953.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42463 16-Dec-15 2015_12 FBgn0022325 l(1)A36.3 lethal (1) A36.3 http://flybase.net/reports/FBgn0022325.html gene A36.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0044423 M80-A33 M80-A33 http://flybase.net/reports/FBgn0044423.html gene 0001754=eye photoreceptor cell differentiation M80#A33 16-Dec-15 2015_12 "eye photoreceptor cell,somatic clone" FBgn0265864 CR44653 http://flybase.net/reports/FBgn0265864.html non_protein_coding_gene CR44653 16-Dec-15 2015_12 FBgn0033998 row relative of woc http://flybase.net/reports/FBgn0033998.html FBgn0062179 protein_coding_gene "0003682=chromatin binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding, 0003677=DNA binding, 0005515=protein binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" "0000791=euchromatin, 0005634=nucleus, 0043234=protein complex" "Relative-of-WOC, anon-WO0118547.194, Row, row, CG8092" "IPR007087=Zinc finger, C2H2, IPR029795=SNAIL family, IPR015880=Zinc finger, C2H2-like, IPR017956=AT hook, DNA-binding motif" CG8092 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,viable,planar polarity defective,fertile,lethal" FBgn0034482 CG18416 http://flybase.net/reports/FBgn0034482.html protein_coding_gene 16-Dec-15 2015_12 FBgn0043037 l(2)42Bg lethal (2) 42Bg http://flybase.net/reports/FBgn0043037.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001736 l(1)HM4 lethal (1) HM4 http://flybase.net/reports/FBgn0001736.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0050467 CG30467 http://flybase.net/reports/FBgn0050467.html FBgn0034026 protein_coding_gene CG8185 CG30467 16-Dec-15 2015_12 viable FBgn0010765 l(3)01969 lethal (3) 01969 http://flybase.net/reports/FBgn0010765.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025516 fs(3)82CDb fs(3)82CDb http://flybase.net/reports/FBgn0025516.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0000426 SmF Small ribonucleoprotein particle protein SmF http://flybase.net/reports/FBgn0000426.html FBgn0063188 protein_coding_gene 0003723=RNA binding "0000398=mRNA splicing, via spliceosome, 0007052=mitotic spindle organization" "0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex, 0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0005732=small nucleolar ribonucleoprotein complex" "dF, F-Sm, DebB, Developmental embryonic B, BcDNA:GM23968, Deb, CG16792, deb-b, snRNP-F, Deb-B" "IPR001163=LSM domain, eukaryotic/archaea-type, IPR010920=LSM domain, IPR016487=Sm-like protein Lsm6/SmF" CG16792 16-Dec-15 2015_12 ENSDARG00000036570(snrpfl) YPR182W(SMX3) WBGene00004918(snr-5) ENSXETG00000021630(SNRPF) ENSMUSG00000020018(Snrpf) ENSG00000139343(SNRPF) FBgn0044020 Roc2 Regulator of cullins 2 http://flybase.net/reports/FBgn0044020.html "FBgn0033641, FBgn0062983" protein_coding_gene "0061630=ubiquitin protein ligase activity, 0097602=cullin family protein binding, 0008270=zinc ion binding" 0016567=protein ubiquitination "0005829=cytosol, 0031466=Cul5-RING ubiquitin ligase complex" "CG8998, dRoc2, BcDNA:RE61847, roc2, Roc2, Roc" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR024766=Zinc finger, RING-H2-type, IPR001841=Zinc finger, RING-type" CG8998 16-Dec-15 2015_12 ENSDARG00000055524(rnf7) WBGene00019993(rbx-2) ENSXETG00000014753(RNF7) "ENSMUSG00000051234(Rnf7),ENSMUSG00000048185(Gm7075)" ENSG00000114125(RNF7) embryonic stage -- adult stage organism

"viable,fertile" FBgn0053982 CG33982 http://flybase.net/reports/FBgn0053982.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036481 CG16959 http://flybase.net/reports/FBgn0036481.html protein_coding_gene CT21630 CG16959 16-Dec-15 2015_12 DRSC10230 K -0.444727648 0.105054455 -0.277317384 0.398751476 -1.527998163 -0.208738344 FBgn0067334 sd::vg sd::vg http://flybase.net/reports/FBgn0067334.html engineered_fusion_gene 16-Dec-15 2015_12 "scutellum,thorax,macrochaeta" FBgn0029101 anon-85Cc anon-85Cc http://flybase.net/reports/FBgn0029101.html gene 16-Dec-15 2015_12 FBgn0013473 l(1)12P2 lethal (1) 12P2 http://flybase.net/reports/FBgn0013473.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/first instar larval cuticle,germline clone" FBgn0266711 EloC Elongin C http://flybase.net/reports/FBgn0266711.html "FBgn0023211, FBgn0062906, FBgn0065422" protein_coding_gene "0048813=dendrite morphogenesis, 0022008=neurogenesis, 0006511=ubiquitin-dependent protein catabolic process, 0007474=imaginal disc-derived wing vein specification" "0008023=transcription elongation factor complex, 0070449=elongin complex, 0005705=polytene chromosome interband, 0031462=Cul2-RING ubiquitin ligase complex, 0005700=polytene chromosome" "dElongin C, BcDNA:RH71704, ElonginC, Elongin C, l(2)SH1299, d-elongin C, l(2)SH2 1520, l(2)SH1520, Elongin-C, lethal (2) SH1520, elongin C, CG9291" "IPR016073=SKP1 component, POZ domain, IPR001232=S-phase kinase-associated protein 1-like, IPR011333=POZ domain" CG9291 16-Dec-15 2015_12 "ENSDARG00000045359(tceb1b),ENSDARG00000045355(tceb1a)" YPL046C(ELC1) WBGene00001236(elc-1) ENSXETG00000011828(tceb1) ENSMUSG00000079658(Tceb1) ENSG00000154582(TCEB1) FBgn0015400 kek2 kekkon-2 http://flybase.net/reports/FBgn0015400.html protein_coding_gene 0042059=negative regulation of epidermal growth factor receptor signaling pathway 0005887=integral component of plasma membrane "NB7, Kekkon-2, kekkon, CT15962, CG4977, Kek2" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR007110=Immunoglobulin-like domain, IPR003591=Leucine-rich repeat, typical subtype, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR001611=Leucine-rich repeat" CG4977 16-Dec-15 2015_12 "ENSDARG00000071230(sc:d0343),ENSDARG00000027602(zgc:63670)" ENSXETG00000017309(slitl2) ENSMUSG00000072290(Igsf10) "ENSG00000167178(ISLR2),ENSG00000129009(ISLR)" " embryonic stage , embryonic stage | stage 11 " " central nervous system | restricted

, head | lateral

, ventral midline | precursor

, ventral midline

, embryonic peripheral nervous system

" "viable,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" FBgn0259626 B1506 http://flybase.net/reports/FBgn0259626.html gene 16-Dec-15 2015_12 visible wing FBgn0263905 l(3)ML72 http://flybase.net/reports/FBgn0263905.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0024568 l(3)L7012 lethal (3) L7012 http://flybase.net/reports/FBgn0024568.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259705 CG42359 http://flybase.net/reports/FBgn0259705.html "FBgn0038684, FBan0005558, FBgn0036884" protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response, 0070072=vacuolar proton-transporting V-type ATPase complex assembly" CG5558 IPR019013=Vacuolar ATPase assembly integral membrane protein Vma21 CG42359 16-Dec-15 2015_12 FBgn0005061 fs(2)OW107 female sterile (2) OW107 http://flybase.net/reports/FBgn0005061.html gene 16-Dec-15 2015_12 FBgn0034140 Lst Limostatin http://flybase.net/reports/FBgn0034140.html protein_coding_gene "0050848=regulation of calcium-mediated signaling, 0070328=triglyceride homeostasis, 0090278=negative regulation of peptide hormone secretion, 0042593=glucose homeostasis, 0009267=cellular response to starvation, 0071322=cellular response to carbohydrate stimulus" "lst, CG8317" CG8317 16-Dec-15 2015_12 viable FBgn0031495 GABPI ë_4GalNAcTB pilot http://flybase.net/reports/FBgn0031495.html protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0008270=zinc ion binding" "0006888=ER to Golgi vesicle-mediated transport, 0018345=protein palmitoylation" 0005794=Golgi apparatus CG17257 "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17257 16-Dec-15 2015_12 "ENSDARG00000003899(zdhhc23),ENSDARG00000029039(LOC100150190)" ENSMUSG00000036304(Zdhhc23) ENSG00000184307(ZDHHC23) "viable,fertile" FBgn0026254 dali dali http://flybase.net/reports/FBgn0026254.html gene 0046666=retinal cell programmed cell death 16-Dec-15 2015_12 FBgn0001256 ImpL1 Ecdysone-inducible gene L1 http://flybase.net/reports/FBgn0001256.html protein_coding_gene 0005576=extracellular region "IMP-L1, Imp-L1, CG10717" CG10717 16-Dec-15 2015_12 viable FBgn0034143 CG8303 http://flybase.net/reports/FBgn0034143.html protein_coding_gene "0050062=long-chain-fatty-acyl-CoA reductase activity, 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity" 0010025=wax biosynthetic process 0005777=peroxisome "IPR016040=NAD(P)-binding domain, IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase" CG8303 16-Dec-15 2015_12 lethal FBgn0058371 CG40371 http://flybase.net/reports/FBgn0058371.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011102 l(1)Q63a lethal (1) Q63a http://flybase.net/reports/FBgn0011102.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0259712 CG42366 http://flybase.net/reports/FBgn0259712.html "FBan0031711, FBan0031878, FBgn0051711, FBgn0051878" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" 0006468=protein phosphorylation "MAK, IME2, CG31878, CG4588, CG31711" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG42366 16-Dec-15 2015_12 "ENSMUSG00000009828(Ick),ENSMUSG00000021363(Mak)" ENSG00000080823(RAGE) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02760 E 0.288562064 0.159423627 0.019319352 -3.056357154 -0.798472665 0.102270046 FBgn0051730 CG31730 http://flybase.net/reports/FBgn0051730.html protein_coding_gene 0008080=N-acetyltransferase activity "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG31730 16-Dec-15 2015_12 "viable,fertile" FBgn0005503 l(2)24EFa lethal (2) 24EFa http://flybase.net/reports/FBgn0005503.html gene l(2)Gr.I 16-Dec-15 2015_12 "lethal,recessive" FBgn0034083 lbk lambik http://flybase.net/reports/FBgn0034083.html protein_coding_gene "0008407=chaeta morphogenesis, 0048477=oogenesis" "CG8434, Lbk, kekkon-like" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR007110=Immunoglobulin-like domain, IPR003591=Leucine-rich repeat, typical subtype, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat" CG8434 16-Dec-15 2015_12 WBGene00020649(T21D12.9) "ENSXETG00000021481(LRIG3),ENSXETG00000002515(LRIG1),ENSXETG00000013203(LRIG2)" "ENSMUSG00000020105(Lrig3),ENSMUSG00000032913(Lrig2),ENSMUSG00000030029(Lrig1)" "ENSG00000139263(LRIG3),ENSG00000198799(LRIG2),ENSG00000144749(LRIG1)" viable DRSC07178 K 0.638826181 0.216452907 0.420278945 -0.086333741 2.289477171 0.91865363 FBgn0004080 Ars-region15 Autonomous replicating sequence region 15 http://flybase.net/reports/FBgn0004080.html region "Ars15, Ars sequence 15" 16-Dec-15 2015_12 FBgn0259454 C279 http://flybase.net/reports/FBgn0259454.html gene 16-Dec-15 2015_12 visible "wing vein,wing vein L3,wing" FBgn0001510 l(1)10Fd lethal (1) 10Fd http://flybase.net/reports/FBgn0001510.html gene "10, l(1)L10" 16-Dec-15 2015_12 "lethal,recessive" FBgn0003175 px plexus http://flybase.net/reports/FBgn0003175.html "FBgn0022042, FBgn0022054" protein_coding_gene "0008586=imaginal disc-derived wing vein morphogenesis, 0002121=inter-male aggressive behavior" "0005654=nucleoplasm, 0016363=nuclear matrix" "l(2)k08316, l(2)k08134, CG4444" CG4444 16-Dec-15 2015_12 embryonic stage && larval stage larval stage | third instar dorsal mesothoracic disc

"behavior defective,recessive,lethal,viable,fertile,visible,wild-type,somatic clone" "wing,wing vein,ectopic,eye,leg,somatic clone" FBgn0262689 CR43159 http://flybase.net/reports/FBgn0262689.html non_protein_coding_gene CR43159 16-Dec-15 2015_12 FBgn0020899 Su(osk)D20 Suppressor of oskar D20 http://flybase.net/reports/FBgn0020899.html gene D20 16-Dec-15 2015_12 FBgn0267787 CR46118 http://flybase.net/reports/FBgn0267787.html non_protein_coding_gene CR46118 16-Dec-15 2015_12 FBgn0038309 Amt Ammonium transporter http://flybase.net/reports/FBgn0038309.html protein_coding_gene 0008519=ammonium transmembrane transporter activity "0072488=ammonium transmembrane transport, 0050911=detection of chemical stimulus involved in sensory perception of smell, 1903718=cellular response to ammonia" 0016020=membrane CG6499 "IPR024041=Ammonium transporter AmtB-like domain, IPR029020=Ammonium/urea transporter, IPR001905=Ammonium transporter" CG6499 16-Dec-15 2015_12 "YNL142W(MEP2),YGR121C(MEP1),YPR138C(MEP3)" "WBGene00000135(amt-3),WBGene00000134(amt-2)" "lethal,auditory perception defective,viable" FBgn0005487 l(1)ts1808 lethal (1) ts1808 http://flybase.net/reports/FBgn0005487.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0014400 trimmed trimmed http://flybase.net/reports/FBgn0014400.html gene "0007427=epithelial cell migration, open tracheal system, 0007430=terminal branching, open tracheal system" 0005886=plasma membrane 16-Dec-15 2015_12 FBgn0027197 l(2)30Ca lethal (2) 30Ca http://flybase.net/reports/FBgn0027197.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0005347 semi-f semi-forked http://flybase.net/reports/FBgn0005347.html gene semiforked 16-Dec-15 2015_12 macrochaeta FBgn0266390 CR45030 http://flybase.net/reports/FBgn0266390.html non_protein_coding_gene CR45030 16-Dec-15 2015_12 FBgn0060614 l(3)S089904 lethal (3) S089904 http://flybase.net/reports/FBgn0060614.html gene 0899/04 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0002771 ml minute-like http://flybase.net/reports/FBgn0002771.html gene "short-bristle, minutelike, sb" 16-Dec-15 2015_12 "Minute,recessive,viable,reduced,visible,male fertile,female fertile,body color defective" "macrochaeta,trident,wing,wing vein,adult abdomen,female" FBgn0266999 ë±-Cat::ed http://flybase.net/reports/FBgn0266999.html engineered_fusion_gene Ed::alphaCat 16-Dec-15 2015_12 FBgn0267455 CR45805 http://flybase.net/reports/FBgn0267455.html non_protein_coding_gene CR45805 16-Dec-15 2015_12 FBgn0033272 RagC-D Ras-related GTP binding C/D ortholog (H. sapiens) http://flybase.net/reports/FBgn0033272.html protein_coding_gene "0046982=protein heterodimerization activity, 0003924=GTPase activity, 0005525=GTP binding" "0071230=cellular response to amino acid stimulus, 0032008=positive regulation of TOR signaling" "RagC, CG8707, Gtr2, dRagC" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006762=Gtr1/RagA G protein" CG8707 16-Dec-15 2015_12 "ENSDARG00000069829(rragc),ENSDARG00000059154(si:dkey-218f9.9),ENSDARG00000006279(zgc:162165)" YGR163W(GTR2) WBGene00012497(ragc-1) "ENSXETG00000005266(rragc),ENSXETG00000019115(RRAGD)" "ENSMUSG00000028646(Rragc),ENSMUSG00000028278(Rragd)" "ENSG00000116954(RRAGC),ENSG00000025039(RRAGD)" "lethal - all die before end of larval stage,some die during third instar larval stage,size defective,decreased cell number,increased cell number,viable" wing FBgn0029128 tyn trynity http://flybase.net/reports/FBgn0029128.html "FBgn0039991, FBgn0069979, FBgn0069980" protein_coding_gene "0003383=apical constriction, 0007015=actin filament organization, 0016476=regulation of embryonic cell shape, 0007160=cell-matrix adhesion" 0016324=apical plasma membrane "CG17131-ORFB, tyn, SP71, CG17131-ORFA, trynity, CG17131" "IPR001507=Zona pellucida domain, IPR003609=PAN/Apple domain" CG17131 16-Dec-15 2015_12 WBGene00009926(noah-2) "lethal,recessive,viable" "denticle,macrochaeta" FBgn0060745 l(3)S066003 lethal (3) S066003 http://flybase.net/reports/FBgn0060745.html gene 0660/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0086898 dgo diego http://flybase.net/reports/FBgn0086898.html "FBgn0062366, FBgn0062672, FBgn0033552" protein_coding_gene "0042067=establishment of ommatidial planar polarity, 0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity" 0005737=cytoplasm "CG12342, EP2619, Diego, Dgo, EP(2)2619" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG12342 16-Dec-15 2015_12 "ENSMUSG00000034485(Uaca),ENSMUSG00000022246(Rai14),ENSMUSG00000038354(Ankrd35)" DRSC26782 K -0.511511798 0.036467439 0.341789282 0.495235947 0.554868121 1.728533291 FBgn0016763 anon-12Da anon-12Da http://flybase.net/reports/FBgn0016763.html gene 16-Dec-15 2015_12 FBgn0046643 anon-38D.24 anon-38D.24 http://flybase.net/reports/FBgn0046643.html gene 38D.24 16-Dec-15 2015_12 FBgn0033738 DUBAI Deubiquitinating apoptotic inhibitor http://flybase.net/reports/FBgn0033738.html protein_coding_gene "0005515=protein binding, 0004843=ubiquitin-specific protease activity" "1903051=negative regulation of proteolysis involved in cellular protein catabolic process, 0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0043066=negative regulation of apoptotic process" "Q7JQI1, DeUBiquitinating-Apoptotic-Inhibitor, Usp38, CG8830" "IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain" CG8830 16-Dec-15 2015_12 ENSXETG00000017515(USP38) ENSMUSG00000038250(Usp38) "ENSG00000118369(USP35),ENSG00000170185(USP38)" "partially lethal - majority die,some die during pupal stage,locomotor behavior defective,visible" eye DRSC05344 K -0.159364607 -0.770071296 0.379912624 0.36133127 1.530879844 -0.314619114 FBgn0259683 Ir40a Ionotropic receptor 40a http://flybase.net/reports/FBgn0259683.html "FBgn0032983, FBan0005922, FBgn0032982, FBan0005929" protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0004984=olfactory receptor activity, 0015276=ligand-gated ion channel activity" "0050850=positive regulation of calcium-mediated signaling, 0042048=olfactory behavior, 0050907=detection of chemical stimulus involved in sensory perception, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016020=membrane, 0016021=integral component of membrane" "CG5929, DmelIR40a, IR40a, CG42352, CG5922, ionotropic receptor 40a" IPR001320=Ionotropic glutamate receptor CG42352 16-Dec-15 2015_12 FBgn0043978 Su(tor)307-14 Su(tor)307-14 http://flybase.net/reports/FBgn0043978.html gene 307-14 16-Dec-15 2015_12 FBgn0029827 CG6048 http://flybase.net/reports/FBgn0029827.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 2000331=regulation of terminal button organization" SP108 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG6048 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0052768 CR32768 http://flybase.net/reports/FBgn0052768.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0277434 v(2)k14204 http://flybase.net/reports/FBgn0277434.html gene l(2)k14204 16-Dec-15 2015_12 FBgn0022339 brls barrels http://flybase.net/reports/FBgn0022339.html gene 16-Dec-15 2015_12 FBgn0033382 Hydr1 ë±/ë_ hydrolase 1 http://flybase.net/reports/FBgn0033382.html protein_coding_gene 0016298=lipase activity 0006629=lipid metabolic process "Dm.HYDR1, CG8058" "IPR012020=AB-hydrolase ABHD1/2/3, IPR000073=Alpha/beta hydrolase fold-1, IPR000952=Uncharacterised protein family UPF0017, hydrolase-like, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG8058 16-Dec-15 2015_12 ENSDARG00000018809(abhd3) "YMR210W(),YPL095C(EEB1),YBR177C(EHT1)" "WBGene00013358(Y60A3A.7),WBGene00016644(C44C1.5)" ENSXETG00000003147(abhd3) "ENSMUSG00000002475(Abhd3),ENSMUSG00000006638(Abhd1)" "ENSG00000158201(ABHD3),ENSG00000143994(ABHD1)" viable FBgn0036406 CG13484 http://flybase.net/reports/FBgn0036406.html protein_coding_gene IPR028265=M-phase-specific PLK1-interacting protein-like CG13484 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" FBgn0014316 l(3)ry125a lethal (3) ry125a http://flybase.net/reports/FBgn0014316.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260121 2L0419 http://flybase.net/reports/FBgn0260121.html gene 16-Dec-15 2015_12 "lethal,recessive" "imaginal tracheoblast,somatic clone,embryonic/larval tracheal system" FBgn0053265 Muc68E Mucin 68E http://flybase.net/reports/FBgn0053265.html protein_coding_gene "0005201=extracellular matrix structural constituent, 0008061=chitin binding" 0006030=chitin metabolic process "0031012=extracellular matrix, 0005576=extracellular region" "Muc68E, CG33265" IPR002557=Chitin binding domain CG33265 16-Dec-15 2015_12 viable DRSC26478 K 0.258517227 0.189358634 0.100124451 0.181165564 1.686202656 -0.207944779 FBgn0034631 TAF1C-like TATA box-binding protein-associated factor RNA polymerase I subunit C-like http://flybase.net/reports/FBgn0034631.html protein_coding_gene 1901838=positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter "0005730=nucleolus, 0005668=RNA polymerase transcription factor SL1 complex" CG10496 CG10496 16-Dec-15 2015_12 viable FBgn0069066 4B7-11 4B7-11 http://flybase.net/reports/FBgn0069066.html gene 0007293=germarium-derived egg chamber formation 16-Dec-15 2015_12 "egg chamber,germline clone" FBgn0277425 l(3)psg22 http://flybase.net/reports/FBgn0277425.html gene psg22 16-Dec-15 2015_12 FBgn0004010 wgo wings out http://flybase.net/reports/FBgn0004010.html gene wings-out 16-Dec-15 2015_12 wing FBgn0037540 Pbp95 PSEA-binding protein 95kD http://flybase.net/reports/FBgn0037540.html "FBgn0022383, FBgn0046261, FBgn0062071" protein_coding_gene "0003677=DNA binding, 0043565=sequence-specific DNA binding, 0003681=bent DNA binding, 0005515=protein binding" "0065004=protein-DNA complex assembly, 0042795=snRNA transcription from RNA polymerase II promoter, 0042796=snRNA transcription from RNA polymerase III promoter, 0046331=lateral inhibition" 0019185=snRNA-activating protein complex "BEST:LD28511, CG2702, PSEA-binding protein, DmSNAP190, DmPBP, DmSNAPc, anon-WO0118547.359, DmPBP95, Drosophila melanogaster PSE-binding protein 95-kDa subunit" "IPR009057=Homeodomain-like, IPR001005=SANT/Myb domain, IPR017930=Myb domain, IPR017877=Myb-like domain" CG2702 16-Dec-15 2015_12 "viable,visible" "chaeta,mesothoracic tergum" FBgn0029142 P(3)91F P(3)91F http://flybase.net/reports/FBgn0029142.html gene 16-Dec-15 2015_12 FBgn0065875 l(2)SH0245 lethal (2) SH0245 http://flybase.net/reports/FBgn0065875.html gene l(2)SH2 0245 16-Dec-15 2015_12 "lethal,recessive" FBgn0022129 l(2)k06409 lethal (2) k06409 http://flybase.net/reports/FBgn0022129.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033818 CG4712 http://flybase.net/reports/FBgn0033818.html protein_coding_gene IPR025254=Domain of unknown function DUF4201 CG4712 16-Dec-15 2015_12 ENSMUSG00000050677(Ccdc96) viable FBgn0067324 B71 B71 http://flybase.net/reports/FBgn0067324.html gene 16-Dec-15 2015_12 "visible,partially lethal - majority die,viable" chaeta FBgn0044067 GATE\polyprotein polyprotein http://flybase.net/reports/FBgn0044067.html transposable_element_gene 0003676=nucleic acid binding "IPR012337=Ribonuclease H-like domain, IPR008042=Retrotransposon, Pao, IPR008737=Peptidase aspartic, putative, IPR005312=Protein of unknown function DUF1759, IPR015416=Zinc finger, H2C2-type, histone UAS binding" 16-Dec-15 2015_12 FBgn0045847 mdg1\ORF1 ORF1 http://flybase.net/reports/FBgn0045847.html transposable_element_gene 16-Dec-15 2015_12 FBgn0020864 cd-s cardinal-similis http://flybase.net/reports/FBgn0020864.html gene 16-Dec-15 2015_12 FBgn0036887 CG9231 http://flybase.net/reports/FBgn0036887.html protein_coding_gene IPR009432=Protein of unknown function DUF1075 CG9231 16-Dec-15 2015_12 ENSDARG00000063344(zgc:162943) ENSXETG00000026898(FAM162A) "ENSMUSG00000003955(Fam162a),ENSMUSG00000019909(Fam162b)" "ENSG00000114023(FAM162A),ENSG00000183807(FAM162B)" viable FBgn0019677 mor(1)2 mortality gene (1)2 http://flybase.net/reports/FBgn0019677.html gene 16-Dec-15 2015_12 short lived FBgn0035331 MsR1 Myosuppressin receptor 1 http://flybase.net/reports/FBgn0035331.html "FBgn0046618, FBgn0046619" protein_coding_gene "0008188=neuropeptide receptor activity, 0035013=myosuppressin receptor activity, 0004930=G-protein coupled receptor activity" "0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0045932=negative regulation of muscle contraction, 0008344=adult locomotory behavior, 0007193=adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "DMSR-1, CG8985, DMS-receptor1, anon-WO0170980.107, Dm CG8985, DmsR-1, Dromyosuppressin receptor 1, anon-WO0170980.106, DmsR, DMS-R1" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR019427=7TM GPCR, serpentine receptor class w (Srw), IPR000276=G protein-coupled receptor, rhodopsin-like" CG8985 16-Dec-15 2015_12 "ENSDARG00000063156,ENSDARG00000015601" "WBGene00010191(F57B7.1),WBGene00007951(C35A5.7)" "ENSMUSG00000066197(Gpr139),ENSMUSG00000034677(Gpr142)" "ENSG00000180269(GPR139),ENSG00000221981" "viable,partially lethal - majority die,visible,locomotor behavior defective" wing FBgn0052686 CG32686 http://flybase.net/reports/FBgn0052686.html "FBgn0063304, FBgn0066052" protein_coding_gene "anon-WO02059370.11, BcDNA:AT25933" CG32686 16-Dec-15 2015_12 viable FBgn0030992 CG33253 http://flybase.net/reports/FBgn0030992.html "FBgn0025699, FBgn0040889, FBgn0053253" protein_coding_gene 0006909=phagocytosis 0016021=integral component of membrane "unnamed, CG7633, CG14192, BEST:CK01423, CK01423" "IPR018080=Band 7/stomatin-like, conserved site, IPR001107=Band 7 protein, IPR001972=Stomatin family" CG33253 16-Dec-15 2015_12 ENSDARG00000057035(zgc:110200) ENSXETG00000005844() viable DRSC20053 K -0.060614417 0.264020846 0.466298821 -0.098678709 1.620241662 0.119299867 FBgn0031432 Cyp309a1 Cyp309a1 http://flybase.net/reports/FBgn0031432.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" "0046331=lateral inhibition, 0055114=oxidation-reduction process" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "309a1, CG9964, cytochrome P450" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG9964 16-Dec-15 2015_12 YHR007C(ERG11) "lethal,viable,visible" "eye,chaeta,supernumerary" FBgn0033610 CG18335 http://flybase.net/reports/FBgn0033610.html protein_coding_gene IPR018902=Uncharacterised protein family UPF0573/UPF0605 CG18335 16-Dec-15 2015_12 ENSDARG00000069352 ENSMUSG00000026969(Fam166a) ENSG00000215187(FAM166B) FBgn0065239 l(2)SH2160 lethal (2) SH2160 http://flybase.net/reports/FBgn0065239.html gene l(2)SH2 2160 16-Dec-15 2015_12 "lethal,recessive" FBgn0026675 l(1)G0113 lethal (1) G0113 http://flybase.net/reports/FBgn0026675.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028020 l(3)S104103 lethal (3) S104103 http://flybase.net/reports/FBgn0028020.html gene 1041/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0001390 l(1)2Ca lethal (1) 2Ca http://flybase.net/reports/FBgn0001390.html gene l(1)C282 16-Dec-15 2015_12 "lethal,recessive" FBgn0028546 ics icarus http://flybase.net/reports/FBgn0028546.html protein_coding_gene 0030695=GTPase regulator activity "0046329=negative regulation of JNK cascade, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0043508=negative regulation of JUN kinase activity, 0007229=integrin-mediated signaling pathway" "Ras suppressor-1, BG:BACR48E02.4, Rsu-1, CG9031, RSU-1, CT25926, RSU1, Ras Suppressor-1" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG9031 16-Dec-15 2015_12 ENSDARG00000045279(rsu1) WBGene00007924(C34C12.5) ENSXETG00000007451(rsu1) ENSMUSG00000026727(Rsu1) ENSG00000148484(RSU1) "viable,fertile,visible,recessive" wing blade FBgn0038768 CG4936 http://flybase.net/reports/FBgn0038768.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "0046580=negative regulation of Ras protein signal transduction, 0070373=negative regulation of ERK1 and ERK2 cascade" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4936 16-Dec-15 2015_12 "WBGene00003087(lsy-2),WBGene00009937(lsl-1)" "ENSMUSG00000046792(Zfp787),ENSMUSG00000054716(Zfp771),ENSMUSG00000042097(Zfp239)" "visible,partially lethal - majority die,some die during pupal stage,female fertile,lethal,recessive" "trichogen cell,mesothoracic tergum" DRSC15680 IK -0.998708715 1.710819521 1.086085404 1.185087604 0.729240615 1.551195212 FBgn0004156 l(2)51Dc lethal (2) 51Dc http://flybase.net/reports/FBgn0004156.html gene 16-Dec-15 2015_12 "lethal,polyphasic" FBgn0010136 l(2)57 lethal (2) 57 http://flybase.net/reports/FBgn0010136.html gene 16-Dec-15 2015_12 FBgn0064192 arm::Pen arm::Pen http://flybase.net/reports/FBgn0064192.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0051287 CG31287 http://flybase.net/reports/FBgn0051287.html FBgn0045192 protein_coding_gene 0006886=intracellular protein transport "0016021=integral component of membrane, 0005783=endoplasmic reticulum" NEST:bs24f08 IPR008417=B-cell receptor-associated protein 29/31 CG31287 16-Dec-15 2015_12 viable FBgn0265147 CR44216 http://flybase.net/reports/FBgn0265147.html non_protein_coding_gene lincRNA.131 CR44216 16-Dec-15 2015_12 FBgn0263403 CG43449 http://flybase.net/reports/FBgn0263403.html protein_coding_gene lincRNA.748 CG43449 16-Dec-15 2015_12 FBgn0033538 CG11883 http://flybase.net/reports/FBgn0033538.html protein_coding_gene 0008253=5'-nucleotidase activity 0009166=nucleotide catabolic process "IPR008334=5'-Nucleotidase, C-terminal, IPR029052=Metallo-dependent phosphatase-like, IPR006179=5'-Nucleotidase/apyrase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG11883 16-Dec-15 2015_12 ENSMUSG00000021718(4933425L06Rik) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0015303 Su(SD)3BPi Suppressor of SD 3BPi http://flybase.net/reports/FBgn0015303.html gene 16-Dec-15 2015_12 FBgn0032336 AstC Allatostatin C http://flybase.net/reports/FBgn0032336.html "FBgn0043835, FBgn0047021" protein_coding_gene "0005179=hormone activity, 0005184=neuropeptide hormone activity, 0016085=myoinhibitory hormone activity" "0045968=negative regulation of juvenile hormone biosynthetic process, 0010459=negative regulation of heart rate, 0007218=neuropeptide signaling pathway, 0008016=regulation of heart contraction" 0005615=extracellular space "flatline, BEST:GH06087, AstC, DAP-C, ast2, ASC, Flt, Drostatin-C, Allatostatin Manduca-type, Ast-C, ASTC, Ast2, FLT, M-ASH, AST-C, Drm-AST C, flt, allatostatin C, CG149199, allatostatin-C, CG14919, drostatin-C, BcDNA:RH36507, gh06087, Allatostatin 2, Drm-AST-C" "IPR020161=Allatostatin, insect" CG14919 16-Dec-15 2015_12 viable FBgn0259701 CG42355 http://flybase.net/reports/FBgn0259701.html "FBan0032308, FBgn0052308" protein_coding_gene CG32308 "IPR024460=Protein of unknown function DUF1074, IPR009071=High mobility group box domain" CG42355 16-Dec-15 2015_12 viable FBgn0037486 CG14605 http://flybase.net/reports/FBgn0037486.html FBgn0063325 protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane BcDNA:AT16877 "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like" CG14605 16-Dec-15 2015_12 viable FBgn0001472 l(1)9Ea lethal (1) 9Ea http://flybase.net/reports/FBgn0001472.html gene "l(1)EM22, EM31, l(1)EM32" 16-Dec-15 2015_12 lethal FBgn0069114 mus216 mutagen-sensitive 216 http://flybase.net/reports/FBgn0069114.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0003463 sog short gastrulation http://flybase.net/reports/FBgn0003463.html "FBgn0027206, FBgn0028353, FBgn0029046" protein_coding_gene "0005518=collagen binding, 0008083=growth factor activity" "0007362=terminal region determination, 0007313=maternal specification of dorsal/ventral axis, oocyte, soma encoded, 0030509=BMP signaling pathway, 0008293=torso signaling pathway, 0007378=amnioserosa formation, 0061328=posterior Malpighian tubule development, 0007398=ectoderm development, 0030510=regulation of BMP signaling pathway, 0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0030511=positive regulation of transforming growth factor beta receptor signaling pathway, 0007354=zygotic determination of anterior/posterior axis, embryo, 0035271=ring gland development, 0008586=imaginal disc-derived wing vein morphogenesis" "0005886=plasma membrane, 0016021=integral component of membrane" "CG9224, Chordin, Short gastrulation, l(1)G0160, l(1)G0479, SOG, Short Gastrulation, short of gastrulation, Sog, Dm sog, short-gastrulation, l(1)G0395" "IPR001007=VWFC domain, IPR010895=CHRD, IPR016353=Chordin" CG9224 16-Dec-15 2015_12 ENSDARG00000006110(chd) ENSXETG00000017290(CHRD) ENSMUSG00000006958(Chrd) ENSG00000090539(CHRD) " larval stage , embryonic stage | stage 5 , pupal stage | 18-20 hr , embryonic stage | stage 10 , embryonic stage | cycle 13,14 , embryonic stage | stage 8 , embryonic stage | stage 12 , pupal stage | 25-30 hr " " dorsal mesothoracic disc | restricted

, ventral thoracic disc | restricted

, ventral neurogenic region

, wing cell | subset

, organism | lateral & striped

,

lateral , ventral midline

, endoderm | restricted

, wing cell

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,dominant,partially lethal - majority die,lethal,maternal effect,somatic clone,heat sensitive,wild-type,neuroanatomy defective,viable" "embryo,posterior crossvein,wing vein L3,wing vein L4,wing vein L5,wing vein,wing vein L2,ectopic,embryonic/first instar larval cuticle,denticle belt,maternal effect,somatic clone,embryonic epidermis,dorsal appendage,egg operculum,amnioserosa,chorion,heat sensitive,presumptive embryonic/larval peripheral nervous system,dorsal abdominal cluster,lateral abdominal cluster,dorsal closure embryo,embryonic/larval dorsal trunk,embryonic/larval visceral branch,embryonic/larval dorsal branch,mandibular segment,cuticle,extended germ band embryo,ventral neurectoderm,adult salivary gland primordium,filzkorper,embryonic head,denticle,embryonic Malpighian tubule,corpus cardiacum primordium,wing,anterior crossvein,distal,anterior,crossvein,supernumerary,scutellar bristle,eye,antenna,wing cell" DRSC20379 K -0.244815193 0.078516105 1.317291769 0.239538143 2.099123951 1.67880489 FBgn0030539 CG1368 http://flybase.net/reports/FBgn0030539.html protein_coding_gene 0005213=structural constituent of chorion IPR004019=YLP motif CG1368 16-Dec-15 2015_12 FBgn0001582 l(1)C lethal (1) C http://flybase.net/reports/FBgn0001582.html gene 16-Dec-15 2015_12 lethal FBgn0265542 CR44392 http://flybase.net/reports/FBgn0265542.html non_protein_coding_gene CR44392 16-Dec-15 2015_12 FBgn0264866 CR44057 http://flybase.net/reports/FBgn0264866.html non_protein_coding_gene lincRNA.30 CR44057 16-Dec-15 2015_12 FBgn0065861 l(2)SH0273 lethal (2) SH0273 http://flybase.net/reports/FBgn0065861.html gene l(2)SH2 0273 16-Dec-15 2015_12 "lethal,recessive" FBgn0037608 mRpL19 mitochondrial ribosomal protein L19 http://flybase.net/reports/FBgn0037608.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "L19, CG8039" "IPR008991=Translation protein SH3-like domain, IPR001857=Ribosomal protein L19" CG8039 16-Dec-15 2015_12 ENSDARG00000011885(mrpl19) WBGene00022470(Y119C1B.4) ENSXETG00000018198(MRPL19) ENSMUSG00000030045(Mrpl19) ENSG00000115364(MRPL19) "viable,visible,lethal,recessive" trichogen cell FBgn0032649 CG15145 http://flybase.net/reports/FBgn0032649.html protein_coding_gene IPR026720=Protein MAATS1 CG15145 16-Dec-15 2015_12 ENSDARG00000006292(si:dkey-265i7.2) ENSXETG00000018054(C3orf15) ENSMUSG00000022805(4932425I24Rik) ENSG00000183833(C3orf15) viable FBgn0040355 CG3526 http://flybase.net/reports/FBgn0040355.html FBgn0029640 protein_coding_gene 0008270=zinc ion binding EG:BACR43E12.4 "IPR000433=Zinc finger, ZZ-type, IPR015880=Zinc finger, C2H2-like, IPR008598=Drought induced 19 protein type, zinc-binding domain" CG3526 16-Dec-15 2015_12 "ENSXETG00000024007(znf313),ENSXETG00000011251(RNF166),ENSXETG00000004739(TEgg015c15.1)" "partially lethal - majority die,some die during pupal stage" FBgn0085107 2.15.43a 2.15.43a http://flybase.net/reports/FBgn0085107.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0040168 l(1)G0366 lethal (1) G0366 http://flybase.net/reports/FBgn0040168.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000622 e(y)6 enhancer of yellow 6 http://flybase.net/reports/FBgn0000622.html gene 16-Dec-15 2015_12 "male sterile,recessive,visible" "macrochaeta,wing,adult cuticle" FBgn0060435 l(3)S125104b lethal (3) S125104b http://flybase.net/reports/FBgn0060435.html gene 1251/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0002110 l(2)1323 lethal (2) 1323 http://flybase.net/reports/FBgn0002110.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000129 Ars-region7 Autonomous replicating sequence region 7 http://flybase.net/reports/FBgn0000129.html region "Ars7, ars410, Ars sequence 7" 16-Dec-15 2015_12 FBgn0058189 CG40189 http://flybase.net/reports/FBgn0058189.html FBan0040189 protein_coding_gene 16-Dec-15 2015_12 FBgn0262101 CG42854 http://flybase.net/reports/FBgn0262101.html protein_coding_gene CG42854 16-Dec-15 2015_12 FBgn0067900 IM22 Immune induced molecule 22 http://flybase.net/reports/FBgn0067900.html gene 0006952=defense response 0005576=extracellular region DIM 22 16-Dec-15 2015_12 FBgn0067750 l(1)G0195 lethal (1) G0195 http://flybase.net/reports/FBgn0067750.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0043042 l(2)42Aa lethal (2) 42Aa http://flybase.net/reports/FBgn0043042.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067401 Rst(2)DDT-WIS1lab Resistant to DDT on II Wisconsin 1 lab http://flybase.net/reports/FBgn0067401.html gene "0017085=response to insecticide, 0046680=response to DDT" 16-Dec-15 2015_12 chemical resistant FBgn0039784 CG9698 http://flybase.net/reports/FBgn0039784.html protein_coding_gene "0005506=iron ion binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0031418=L-ascorbic acid binding, 0004656=procollagen-proline 4-dioxygenase activity" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" "0005783=endoplasmic reticulum, 0016222=procollagen-proline 4-dioxygenase complex" CG9698-E "IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain" CG9698 16-Dec-15 2015_12 "viable,fertile" FBgn0013708 mt:tRNA:V mitochondrial valine tRNA http://flybase.net/reports/FBgn0013708.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006313, tRNA-Val, CR34095, valine tRNA" CR34095 16-Dec-15 2015_12 FBgn0261858 CG42787 http://flybase.net/reports/FBgn0261858.html protein_coding_gene "Mozart1, Mitotic spindle OrganiZing protein Associated with a Ring of g-Tubulin, MOZART1, Mzt1" IPR022214=Protein of unknown function DUF3743 CG42787 16-Dec-15 2015_12 FBgn0000122 Ars Arylsulfatase http://flybase.net/reports/FBgn0000122.html gene 0004065=arylsulfatase activity ARS 16-Dec-15 2015_12 FBgn0003290 Rst(3)FU Resistant to fluorouracil http://flybase.net/reports/FBgn0003290.html gene Resistance (3) Fluorouracil 16-Dec-15 2015_12 chemical resistant FBgn0005338 pxl proximalless http://flybase.net/reports/FBgn0005338.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile,female sterile" photoreceptor FBgn0259587 GG01326 http://flybase.net/reports/FBgn0259587.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing cell,tarsal segment,unguis" FBgn0001544 l(1)15Aa lethal (1) 15Aa http://flybase.net/reports/FBgn0001544.html gene "i15b, l(1)l7, l7, l(1)i15b" 16-Dec-15 2015_12 lethal FBgn0039883 RhoGAP100F Rho GTPase activating protein at 100F http://flybase.net/reports/FBgn0039883.html protein_coding_gene 0005096=GTPase activator activity "0097479=synaptic vesicle localization, 0090630=activation of GTPase activity, 0048846=axon extension involved in axon guidance, 0048790=maintenance of presynaptic active zone structure, 0048789=cytoskeletal matrix organization at active zone, 0045467=R7 cell development, 0007266=Rho protein signal transduction" 0048786=presynaptic active zone "DSyd1, CG1976, syd-1, DSyd-1, 1976, RHOGAP100F, Syd-1, dsyd-1, synpase defective-1, RhoGAP100F" "IPR000198=Rho GTPase-activating protein domain, IPR000008=C2 domain, IPR008936=Rho GTPase activation protein, IPR001478=PDZ domain" CG1976 16-Dec-15 2015_12 WBGene00006363(syd-1) "neuroanatomy defective,somatic clone" "photoreceptor cell R7,somatic clone" DRSC28096 K 0.043073573 -0.253606431 0.351996241 0.430394115 0.325407229 2.437494716 FBgn0263211 CR43381 http://flybase.net/reports/FBgn0263211.html pseudogene_attribute CR43381 16-Dec-15 2015_12 FBgn0003752 translucent translucent http://flybase.net/reports/FBgn0003752.html gene trl 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0060366 l(3)S138112 lethal (3) S138112 http://flybase.net/reports/FBgn0060366.html gene 1381/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065979 iab-6-2.s iab-6-2.s http://flybase.net/reports/FBgn0065979.html gene 6-2.s 16-Dec-15 2015_12 FBgn0001745 l(1)HM17 lethal (1) HM17 http://flybase.net/reports/FBgn0001745.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0069227 gl(2L)386-2 gl(2L)386-2 http://flybase.net/reports/FBgn0069227.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0065574 l(2)SH0955 lethal (2) SH0955 http://flybase.net/reports/FBgn0065574.html gene l(2)SH2 0955 16-Dec-15 2015_12 "lethal,recessive" FBgn0030735 CG3632 http://flybase.net/reports/FBgn0030735.html protein_coding_gene "0008138=protein tyrosine/serine/threonine phosphatase activity, 0046872=metal ion binding, 0004722=protein serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0006470=protein dephosphorylation, 0035335=peptidyl-tyrosine dephosphorylation" 0005737=cytoplasm MYOTUBULARIN-like "IPR010569=Myotubularin-like phosphatase domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR030564=Myotubularin family, IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR000387=Tyrosine specific protein phosphatases domain, IPR000306=FYVE zinc finger, IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site" CG3632 16-Dec-15 2015_12 WBGene00003476(mtm-3) "ENSXETG00000016428(MTMR3),ENSXETG00000007790(MTMR4)" "ENSMUSG00000018401(Mtmr4),ENSMUSG00000034354(Mtmr3)" "ENSG00000108389(MTMR4),ENSG00000100330(MTMR3)" "visible,viable,fertile" "wing vein,ectopic,trichogen cell" FBgn0036837 CG18135 http://flybase.net/reports/FBgn0036837.html protein_coding_gene "0008081=phosphoric diester hydrolase activity, 2001070=starch binding, 0017022=myosin binding" "0006629=lipid metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR013784=Carbohydrate-binding-like fold, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR013783=Immunoglobulin-like fold, IPR002044=Carbohydrate binding module family 20, IPR030395=Glycerophosphodiester phosphodiesterase domain" CG18135 16-Dec-15 2015_12 "viable,fertile" FBgn0058113 CG40113 http://flybase.net/reports/FBgn0058113.html FBan0040113 protein_coding_gene 16-Dec-15 2015_12 FBgn0053072 CG33072 http://flybase.net/reports/FBgn0053072.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028256 l(3)76BDg lethal (3) 76BDg http://flybase.net/reports/FBgn0028256.html gene 0048515=spermatid differentiation 16-Dec-15 2015_12 "male sterile,lethal,recessive" FBgn0268008 T:GPI-dally GPI domain of dally http://flybase.net/reports/FBgn0268008.html engineered_tag 16-Dec-15 2015_12 FBgn0001354 l(1)1EFc lethal (1) 1EFc http://flybase.net/reports/FBgn0001354.html gene l(1)BA3 16-Dec-15 2015_12 lethal FBgn0035437 Strip Striatin interacting protein http://flybase.net/reports/FBgn0035437.html protein_coding_gene "0046579=positive regulation of Ras protein signal transduction, 0048675=axon extension, 0007032=endosome organization, 0070374=positive regulation of ERK1 and ERK2 cascade" "Striatin interacting protein, Striatin interacting protein ortholog, CG11526, strip" "IPR021819=Protein of unknown function DUF3402, IPR012486=N1221-like" CG11526 16-Dec-15 2015_12 "ENSDARG00000071628,ENSDARG00000071599,ENSDARG00000059003(LOC556392)" WBGene00017349(farl-11) "ENSMUSG00000014601(Fam40a),ENSMUSG00000039629(Fam40b)" "ENSG00000143093(FAM40A),ENSG00000128578(FAM40B)" "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" FBgn0082679 E(ftz)4236 E(ftz)4236 http://flybase.net/reports/FBgn0082679.html gene 4236 16-Dec-15 2015_12 FBgn0050464 Ir52d Ionotropic receptor 52d http://flybase.net/reports/FBgn0050464.html FBgn0034024 protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG12961, IR52d, CG30464, ionotropic receptor 52d, DmelIR52d" CG30464 16-Dec-15 2015_12 viable FBgn0035998 CG3437 http://flybase.net/reports/FBgn0035998.html protein_coding_gene IPR005062=SAC3/GANP/THP3 CG3437 16-Dec-15 2015_12 ENSDARG00000071271(LOC100329353) WBGene00006466(tag-115) ENSMUSG00000024790(Sac3d1) ENSG00000168061(SAC3D1) viable FBgn0028284 l(1)G0412 lethal (1) G0412 http://flybase.net/reports/FBgn0028284.html gene 16-Dec-15 2015_12 "lethal,recessive" pupa FBgn0004694 Su(var)2-2 Suppressor of variegation 2-2 http://flybase.net/reports/FBgn0004694.html gene Su-var(2)2 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0030218 CG1628 http://flybase.net/reports/FBgn0030218.html protein_coding_gene "0022857=transmembrane transporter activity, 0015171=amino acid transmembrane transporter activity, 0000064=L-ornithine transmembrane transporter activity" "0000066=mitochondrial ornithine transport, 0006839=mitochondrial transport, 0003333=amino acid transmembrane transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG1628 16-Dec-15 2015_12 ENSDARG00000062271(LOC565335) YOR130C(ORT1) WBGene00020422(T10F2.2) "ENSXETG00000020872(),ENSXETG00000027202(Q5FVV4_XENTR),ENSXETG00000020700()" "ENSMUSG00000031482(Slc25a15),ENSMUSG00000050304" "ENSG00000102743(SLC25A15),ENSG00000120329(SLC25A2)" "partially lethal - majority die,some die during pupal stage" FBgn0005123 l(1)nib lethal no imaginal buds http://flybase.net/reports/FBgn0005123.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "melanotic mass,embryonic/larval digestive system,imaginal disc primordium" FBgn0021850 l(2)k14603b lethal (2) k14603b http://flybase.net/reports/FBgn0021850.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014022 Rlb1 Rlb1 http://flybase.net/reports/FBgn0014022.html protein_coding_gene "0016020=membrane, 0005634=nucleus" "CG8161, Rlb, Ov30" CG8161 16-Dec-15 2015_12 viable FBgn0062598 Mod(var)1485 Mod(var)1485 http://flybase.net/reports/FBgn0062598.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1485 16-Dec-15 2015_12 "suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0263411 CR43457 http://flybase.net/reports/FBgn0263411.html non_protein_coding_gene lincRNA.847 CR43457 16-Dec-15 2015_12 FBgn0036382 CG13737 http://flybase.net/reports/FBgn0036382.html protein_coding_gene CG13737 16-Dec-15 2015_12 FBgn0023540 CG3630 http://flybase.net/reports/FBgn0023540.html protein_coding_gene 0003779=actin binding 0035025=positive regulation of Rho protein signal transduction 0015629=actin cytoskeleton "EG:152A3.3, 152A3.3" IPR027817=Costars domain CG3630 16-Dec-15 2015_12 WBGene00044078(tag-243) "viable,fertile" DRSC28903 K 0.295156162 0.036560969 0.727557886 0.04233369 0.558635196 2.510713194 FBgn0086355 Tpi Triose phosphate isomerase http://flybase.net/reports/FBgn0086355.html "FBgn0003738, FBgn0063906" protein_coding_gene 0004807=triose-phosphate isomerase activity "0007525=somatic muscle development, 0006096=glycolytic process, 0050877=neurological system process, 0019682=glyceraldehyde-3-phosphate metabolic process, 0007520=myoblast fusion, 0009612=response to mechanical stimulus, 0008340=determination of adult lifespan" "0030018=Z disc, 0031430=M band" "ND14, Triosephosphate isomerase, wasted away, sgk, Neurodegeneration 14, Tpi, TPIS, CG2171, wstd, tpi, TPI, triosephosphate isomerase, triose phosphate isomerase, sugarkill" "IPR022896=Triosephosphate isomerase, bacterial/eukaryotic, IPR020861=Triosephosphate isomerase, active site, IPR013785=Aldolase-type TIM barrel, IPR000652=Triosephosphate isomerase" CG2171 16-Dec-15 2015_12 "ENSDARG00000040988(tpi1b),ENSDARG00000025012(tpi1a)" YDR050C(TPI1) WBGene00006601(tpi-1) ENSXETG00000023924(TPI1) ENSMUSG00000023456(Tpi1) ENSG00000111669(TPI1) embryonic stage -- adult stage larval stage | third instar dorsal mesothoracic disc

FBgn0028589 l(3)L7160a lethal (3) L7160a http://flybase.net/reports/FBgn0028589.html gene l(3)L7160 16-Dec-15 2015_12 "lethal,recessive" FBgn0028348 l(1)G0181 lethal (1) G0181 http://flybase.net/reports/FBgn0028348.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035109 CG13876 http://flybase.net/reports/FBgn0035109.html protein_coding_gene IPR026698=Uncharacterised protein C3orf38 (DUF4518) CG13876 16-Dec-15 2015_12 ENSXETG00000007628(TEgg097j12.1) ENSMUSG00000059920(4930453N24Rik) ENSG00000179021(C3orf38) viable FBgn0262993 CR43301 http://flybase.net/reports/FBgn0262993.html non_protein_coding_gene CR43301 16-Dec-15 2015_12 FBgn0261601 M(1)5D6A Minute (1) 5D6A http://flybase.net/reports/FBgn0261601.html gene 16-Dec-15 2015_12 FBgn0060712 l(3)S070116 lethal (3) S070116 http://flybase.net/reports/FBgn0060712.html gene 0701/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0058404 CG40404 http://flybase.net/reports/FBgn0058404.html protein_coding_gene 16-Dec-15 2015_12 FBgn0020513 ade5 ade5 http://flybase.net/reports/FBgn0020513.html protein_coding_gene "0004639=phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, 0005524=ATP binding, 0004638=phosphoribosylaminoimidazole carboxylase activity" "0006189='de novo' IMP biosynthetic process, 0002121=inter-male aggressive behavior, 0007476=imaginal disc-derived wing morphogenesis" "0005737=cytoplasm, 0005829=cytosol" "AIR-carboxylase-SAICAR synthetase, CG3989, Ade5, AIRc-SAICARs" "IPR028923=SAICAR synthetase/ADE2, N-terminal, IPR018236=SAICAR synthetase, conserved site, IPR000031=Phosphoribosylaminoimidazole carboxylase PurE domain, IPR013816=ATP-grasp fold, subdomain 2" CG3989 16-Dec-15 2015_12 YAR015W(ADE1) WBGene00015116(B0286.3) ENSXETG00000005615(PAICS) ENSMUSG00000029247(Paics) ENSG00000128050(PAICS) "behavior defective,recessive,eye color defective,auxotroph,lethal,viable" pigment cell FBgn0085746 CR40571 http://flybase.net/reports/FBgn0085746.html FBan0040571 rRNA_gene CR40571 16-Dec-15 2015_12 FBgn0002400 l(3)99Da lethal (3) 99Da http://flybase.net/reports/FBgn0002400.html gene 16-Dec-15 2015_12 lethal FBgn0015513 mbc myoblast city http://flybase.net/reports/FBgn0015513.html protein_coding_gene "0030676=Rac guanyl-nucleotide exchange factor activity, 0005515=protein binding" "0007523=larval visceral muscle development, 0007519=skeletal muscle tissue development, 0035212=cell competition in a multicellular organism, 0007298=border follicle cell migration, 0030036=actin cytoskeleton organization, 0000902=cell morphogenesis, 0007520=myoblast fusion, 0061327=anterior Malpighian tubule development, 0016203=muscle attachment, 0007417=central nervous system development, 0090630=activation of GTPase activity, 0007391=dorsal closure, 0007010=cytoskeleton organization" "0005737=cytoplasm, 0019897=extrinsic component of plasma membrane, 0001726=ruffle" "Mbc, Myoblast City, CG10379, Myoblast city, MBC/DOCK180, Dock180, dock180, Dm MBC, DOCK180, Su(rac)1, MBC" "IPR026791=Dedicator of cytokinesis, IPR031057=DOCK1 homologue, IPR010703=Dedicator of cytokinesis C-terminal, IPR027007=DHR-1 domain, IPR001452=SH3 domain, IPR027357=DHR-2 domain, IPR000008=C2 domain" CG10379 16-Dec-15 2015_12 WBGene00000419(ced-5) "ENSXETG00000005204(DOCK1),ENSXETG00000019922(DOCK2)" "ENSMUSG00000058325(Dock1),ENSMUSG00000044447(Dock5),ENSMUSG00000020143(Dock2)" "ENSG00000150760(DOCK1),ENSG00000147459(DOCK5),ENSG00000134516(DOCK2)" " embryonic stage | stage >=12 , embryonic stage | stage 12-14 , adult stage | male , adult stage | female , embryonic stage | stage 16 , pupal stage , embryonic stage | stage 12 , embryonic stage | stage 14 , embryonic stage | 0-4 hr , embryonic stage | stage 5 , embryonic stage | stage 7-12 , embryonic stage , embryonic stage | stage 4 " " visceral mesoderm

, somatic mesoderm

, embryonic/larval dorsal vessel

, endoderm

, embryonic/larval visceral muscle

, ectoderm | striped

,

lateral , ectoderm

, pole cell

" " embryonic stage | stage 12 , embryonic stage | stage 16 , embryonic stage | stage 5 , embryonic stage | stage 14 " " endoderm

, myoblast

, embryonic/larval dorsal vessel

, pole cell

, embryonic/larval visceral muscle

, ectoderm

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval somatic muscle,embryonic Malpighian tubule,embryonic myoblast,embryonic dorsal epidermis,axon & ventral nerve cord,longitudinal connective,commissure,border follicle cell,somatic clone,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,germline clone,lateral longitudinal fascicle,muscle founder cell,longitudinal muscle,embryonic/larval muscle system,circular visceral muscle fiber,myoblast,midgut constriction,embryonic visceral muscle,circular visceral muscle primordium,fusion competent cell,embryonic/larval Malpighian tubule,embryonic/larval anterior Malpighian tubule,Malpighian tubule Type II cell,thorax,chaeta,supernumerary,mesothoracic tergum,reticular neuropil associated glial cell,gamma Kenyon cell" FBgn0263388 CR43440 http://flybase.net/reports/FBgn0263388.html non_protein_coding_gene CG43440 CR43440 16-Dec-15 2015_12 FBgn0065119 l(3)SH150 lethal (3) SH150 http://flybase.net/reports/FBgn0065119.html gene l(2)SH3 150 16-Dec-15 2015_12 "lethal,recessive" FBgn0266730 CR45203 http://flybase.net/reports/FBgn0266730.html non_protein_coding_gene CR45203 16-Dec-15 2015_12 FBgn0060322 l(3)S146901 lethal (3) S146901 http://flybase.net/reports/FBgn0060322.html gene 1469/01 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0020892 Su(osk)K6 Suppressor of oskar K6 http://flybase.net/reports/FBgn0020892.html gene K6 16-Dec-15 2015_12 FBgn0003283 rsi reduced size http://flybase.net/reports/FBgn0003283.html gene 16-Dec-15 2015_12 "visible,fertile,viable,reduced" FBgn0267270 CR45706 http://flybase.net/reports/FBgn0267270.html non_protein_coding_gene CR45706 16-Dec-15 2015_12 FBgn0029642 CG3592 http://flybase.net/reports/FBgn0029642.html protein_coding_gene 0016021=integral component of membrane frag7 "IPR006593=Cytochrome b561/ferric reductase transmembrane, IPR004877=Cytochrome b561 domain" CG3592 16-Dec-15 2015_12 viable FBgn0043597 E(roDOM)1065 E(roDOM)1065 http://flybase.net/reports/FBgn0043597.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0003654 sw short wing http://flybase.net/reports/FBgn0003654.html "FBgn0013761, FBgn0031096" protein_coding_gene "0003777=microtubule motor activity, 0045503=dynein light chain binding" "0016482=cytoplasmic transport, 0008088=axon cargo transport, 0034501=protein localization to kinetochore, 0001754=eye photoreceptor cell differentiation, 0051642=centrosome localization, 0007051=spindle organization, 0007349=cellularization, 0000226=microtubule cytoskeleton organization, 0007291=sperm individualization" "0005868=cytoplasmic dynein complex, 0005875=microtubule associated complex" "Dic19C, Dynein Intermediate chain, Cdic2b, cDIC, dynein intermediate chain, dynein, dynein IC, Dynein intermediate-chain, Cytoplasmic dynein intermediate chain, IC74, CG18000, Swallow, 17-234, Dynein intermediate chain, Cytoplasmic dynein, DIC, IC, dic, Dynein Intermediate Chain, Dynein IC, Dic, dynein intermediate-chain, cytoplasmic dynein intermediate polypeptide chain, Dic19B, cytoplasmic dynein, l(1)19Bb, Cdic, cytoplasmic dynein intermediate chain" "IPR025956=Cytoplasmic dynein 1 intermediate chain 1/2, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG18000 16-Dec-15 2015_12 "ENSDARG00000005756(dync1i2a),ENSDARG00000022487,ENSDARG00000060948(zgc:158394),ENSDARG00000063383(dync1i2b)" YDR488C(PAC11) WBGene00015927(dyci-1) "ENSXETG00000020285(dnci2),ENSXETG00000020277(DYNC1I1)" "ENSMUSG00000027012(Dync1i2),ENSMUSG00000029757(Dync1i1)" "ENSG00000077380(DYNC1I2),ENSG00000158560(DYNC1I1)" embryonic stage && adult stage "female sterile,neuroanatomy defective,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,wild-type,lethal,visible,paralytic,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,viable,fertile,reduced,partially lethal - majority die" "wing vein,dendritic arborizing neuron,wing,eye,wing margin,ommatidium,cystic bulge,nucleus & spermatid,mesothoracic tergum" FBgn0267566 CR45906 http://flybase.net/reports/FBgn0267566.html non_protein_coding_gene CR45906 16-Dec-15 2015_12 FBgn0037731 CG18542 http://flybase.net/reports/FBgn0037731.html protein_coding_gene IPR016181=Acyl-CoA N-acyltransferase CG18542 16-Dec-15 2015_12 FBgn0005162 l(2)G305 lethal (2) G305 http://flybase.net/reports/FBgn0005162.html gene 16-Dec-15 2015_12 lethal FBgn0025003 E(var)56-9 E(var)56-9 http://flybase.net/reports/FBgn0025003.html gene E-56/9 16-Dec-15 2015_12 FBgn0021780 l(3)95Ba lethal (3) 95Ba http://flybase.net/reports/FBgn0021780.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003538 Stp-2 Strapped on 2 http://flybase.net/reports/FBgn0003538.html gene Strapped in chromosome 2 16-Dec-15 2015_12 "wing margin,male" FBgn0005220 l(3)ET15 lethal Elaine Tasaka 15 http://flybase.net/reports/FBgn0005220.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" FBgn0263594 lost lost http://flybase.net/reports/FBgn0263594.html "FBgn0082587, FBgn0037245, FBgn0062228" protein_coding_gene 0003723=RNA binding "0000398=mRNA splicing, via spliceosome, 0009952=anterior/posterior pattern specification, 0007277=pole cell development, 0007310=oocyte dorsal/ventral axis specification, 0008298=intracellular mRNA localization, 0019094=pole plasm mRNA localization, 0045451=pole plasm oskar mRNA localization" "0071013=catalytic step 2 spliceosome, 0030529=ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0005737=cytoplasm, 0005829=cytosol" "lost boys, Lost, anon-WO0118547.126, nev, CG14648, neverland, growl, Growl" "IPR024185=5-formyltetrahydrofolate cyclo-ligase-like domain, IPR002698=5-formyltetrahydrofolate cyclo-ligase" CG14648 16-Dec-15 2015_12 ENSDARG00000062042(mthfsd) ENSXETG00000003563(MTHFSD) ENSMUSG00000031816(Mthfsd) ENSG00000103248(MTHFSD) DRSC12002 E 0.27804616 -0.148413885 0.089605695 -1.514069813 0.207309794 1.298666913 FBgn0028106 l(3)S070103 lethal (3) S070103 http://flybase.net/reports/FBgn0028106.html gene 0701/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0060605 l(3)S091009b lethal (3) S091009b http://flybase.net/reports/FBgn0060605.html gene 0910/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0015900 anon-P1609-II anon-P1609-II http://flybase.net/reports/FBgn0015900.html gene 16-Dec-15 2015_12 FBgn0020910 RpL3 Ribosomal protein L3 http://flybase.net/reports/FBgn0020910.html FBgn0025328 protein_coding_gene 0003735=structural constituent of ribosome "0051297=centrosome organization, 0006412=translation, 0051298=centrosome duplication, 0007052=mitotic spindle organization, 0000022=mitotic spindle elongation" "0022626=cytosolic ribosome, 0022625=cytosolic large ribosomal subunit" "CG4863, L3, Rpl3, chr3R:7047878..7048035, ribosomal protein L3, rpL3, anon-EST:GressD4" "IPR009000=Translation protein, beta-barrel domain, IPR000597=Ribosomal protein L3, IPR019926=Ribosomal protein L3, conserved site" CG4863 16-Dec-15 2015_12 ENSDARG00000003599(rpl3) YOR063W(RPL3) WBGene00004414(rpl-3) "ENSXETG00000006914(),ENSXETG00000007221(Q5BKH7_XENTR)" "ENSMUSG00000060036(Rpl3),ENSMUSG00000068262" "ENSG00000100316(RPL3),ENSG00000140986(RPL3L)" embryonic stage " embryonic/larval midgut

, embryonic/larval muscle system

,

ubiquitous , embryonic/larval hindgut

" "lethal,viable" DRSC16834 IEK -2.011441404 -1.203192499 0.25041104 -3.541307955 1.508482165 1.178366178 FBgn0015340 anon-38Aa anon-38Aa http://flybase.net/reports/FBgn0015340.html gene 16-Dec-15 2015_12 FBgn0265204 CR44264 http://flybase.net/reports/FBgn0265204.html non_protein_coding_gene CR44264 16-Dec-15 2015_12 FBgn0032690 CG10333 http://flybase.net/reports/FBgn0032690.html protein_coding_gene "0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0003676=nucleic acid binding" "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome, 0050688=regulation of defense response to virus" "0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome, 0005682=U5 snRNP" "DmPrp28, DmRH19, cg10333" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal" CG10333 16-Dec-15 2015_12 ENSDARG00000021945(ddx23) YDR243C(PRP28) WBGene00017162(ddx-23) ENSMUSG00000003360(Ddx23) ENSG00000174243(DDX23) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026304 anon-16Fe anon-16Fe http://flybase.net/reports/FBgn0026304.html gene HL-XIV 16-Dec-15 2015_12 FBgn0032471 CG5122 http://flybase.net/reports/FBgn0032471.html protein_coding_gene 0004092=carnitine O-acetyltransferase activity IPR000542=Acyltransferase ChoActase/COT/CPT CG5122 16-Dec-15 2015_12 "viable,fertile" FBgn0266550 Snup::Hsap\SSPN http://flybase.net/reports/FBgn0266550.html engineered_fusion_gene 16-Dec-15 2015_12 lethal FBgn0001850 l(1)ts5697 lethal (1) ts5697 http://flybase.net/reports/FBgn0001850.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0030200 RabX2 RabX2 http://flybase.net/reports/FBgn0030200.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport" 0031982=vesicle "DmRabX2, CG2885" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG2885 16-Dec-15 2015_12 viable FBgn0264951 CR44120 http://flybase.net/reports/FBgn0264951.html non_protein_coding_gene CR44120 16-Dec-15 2015_12 FBgn0037822 CG14683 http://flybase.net/reports/FBgn0037822.html protein_coding_gene 0008168=methyltransferase activity "IPR023397=S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain, IPR002903=Ribosomal RNA small subunit methyltransferase H, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG14683 16-Dec-15 2015_12 ENSXETG00000014903() ENSMUSG00000057234(Mett5d1) ENSG00000169519(METTL15) FBgn0023161 Su(mg)1-7 Suppressor of modifier of gypsy 1-7 http://flybase.net/reports/FBgn0023161.html gene 16-Dec-15 2015_12 "visible,recessive" wing FBgn0043549 anon-12Ba anon-12Ba http://flybase.net/reports/FBgn0043549.html gene cDNA F3 16-Dec-15 2015_12 FBgn0266503 s-276 http://flybase.net/reports/FBgn0266503.html gene 16-Dec-15 2015_12 FBgn0022352 anon-25Db anon-25Db http://flybase.net/reports/FBgn0022352.html gene e3 16-Dec-15 2015_12 FBgn0031426 CG18641 http://flybase.net/reports/FBgn0031426.html FBgn0031425 protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" CG11535 "IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold" CG18641 16-Dec-15 2015_12 viable FBgn0037293 CG12007 http://flybase.net/reports/FBgn0037293.html protein_coding_gene 0004663=Rab geranylgeranyltransferase activity "0008360=regulation of cell shape, 0018344=protein geranylgeranylation, 0022008=neurogenesis, 0007155=cell adhesion" 0005968=Rab-protein geranylgeranyltransferase complex "RabGGTalpha, PTAR3" "IPR002088=Protein prenyltransferase, alpha subunit" CG12007 16-Dec-15 2015_12 ENSDARG00000061024(zgc:153107) YJL031C(BET4) WBGene00019778(M57.2) ENSXETG00000014643(rabggta) ENSMUSG00000040472(Rabggta) ENSG00000100949(RABGGTA) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,tormogen cell" FBgn0065578 l(2)SH0949 lethal (2) SH0949 http://flybase.net/reports/FBgn0065578.html gene l(2)SH2 0949 16-Dec-15 2015_12 "lethal,recessive" FBgn0267818 CR46143 http://flybase.net/reports/FBgn0267818.html non_protein_coding_gene CR46143 16-Dec-15 2015_12 FBgn0032752 CG10702 http://flybase.net/reports/FBgn0032752.html protein_coding_gene "0005010=insulin-like growth factor-activated receptor activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0005524=ATP binding" "0018108=peptidyl-tyrosine phosphorylation, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway" 0005887=integral component of plasma membrane "IPR000494=Receptor L-domain, IPR006211=Furin-like cysteine-rich domain, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR003961=Fibronectin type III, IPR006212=Furin-like repeat" CG10702 16-Dec-15 2015_12 "viable,fertile" FBgn0265085 CR44196 http://flybase.net/reports/FBgn0265085.html non_protein_coding_gene CR44196 16-Dec-15 2015_12 FBgn0260801 EP2-430 http://flybase.net/reports/FBgn0260801.html gene 16-Dec-15 2015_12 FBgn0263586 CR43611 http://flybase.net/reports/FBgn0263586.html non_protein_coding_gene CR43611 16-Dec-15 2015_12 FBgn0052692 CG32692 http://flybase.net/reports/FBgn0052692.html protein_coding_gene 16-Dec-15 2015_12 FBgn0050114 CG30114 http://flybase.net/reports/FBgn0050114.html protein_coding_gene CG30114 16-Dec-15 2015_12 FBgn0086219 zex zexless http://flybase.net/reports/FBgn0086219.html gene 16-Dec-15 2015_12 FBgn0002412 l(3)a lethal (3) a http://flybase.net/reports/FBgn0002412.html gene l(3)1 16-Dec-15 2015_12 "lethal,recessive" FBgn0000734 fs(1)288 female sterile (1) 288 http://flybase.net/reports/FBgn0000734.html gene 16-Dec-15 2015_12 FBgn0029089 cypress cypress http://flybase.net/reports/FBgn0029089.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 dendrite | dorsal | embryonic stage FBgn0000744 fs(1)A248 female sterile (1) A248 http://flybase.net/reports/FBgn0000744.html gene 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive" female reproductive system FBgn0011164 l(1)DM-1 lethal (1) DM-1 http://flybase.net/reports/FBgn0011164.html FBgn0010204 gene 16-Dec-15 2015_12 lethal FBgn0058053 CR40053 http://flybase.net/reports/FBgn0058053.html "FBan0040053, FBgn0063742" non_protein_coding_gene "BcDNA:AT11374, CG40053" CR40053 16-Dec-15 2015_12 FBgn0261279 lqfR liquid facets-Related http://flybase.net/reports/FBgn0261279.html "FBgn0010810, FBgn0038962, FBgn0038963, FBgn0040224, FBgn0051170, FBgn0259107, FBgn0042645, FBgn0051285, FBgn0002502, FBgn0004730" protein_coding_gene "0007269=neurotransmitter secretion, 0008283=cell proliferation, 0048488=synaptic vesicle endocytosis, 0048477=oogenesis, 0016192=vesicle-mediated transport, 0030177=positive regulation of Wnt signaling pathway" "0005737=cytoplasm, 0005634=nucleus, 0005769=early endosome, 0016020=membrane, 0005794=Golgi apparatus, 0005802=trans-Golgi network" "CG13854, Liquid facet Related, XII-10, Epsin, l(3)A9, Liquid facets Related, epsin, Liquid facet related, epsin-2, CG31285, Liquid facets-Related, epsin-like, l(3)dsl9, liquid facets related, LqfR, l(3)03685, l(3)XII-10, Lqfr, EpsinR, Tel2, CG31170, epsin02, liquid-facets Related, CG42250, epsinR, l(3)dsl-9, CG13853, lethal (3) SG62, l(3)SG62" "IPR008942=ENTH/VHS, IPR013809=ENTH domain, IPR019337=Telomere length regulation protein, conserved domain, IPR030544=Clathrin interactor 1" CG42250 16-Dec-15 2015_12 "ENSDARG00000025535(clint1),ENSDARG00000054639" DRSC25247 K -0.257400008 -0.01794462 0.087617946 -0.654869014 0.120915882 2.464519502 FBgn0015368 btb bumper-to-bumper http://flybase.net/reports/FBgn0015368.html gene 0003899=DNA-directed RNA polymerase activity "0006383=transcription from RNA polymerase III promoter, 0007422=peripheral nervous system development" 0005666=DNA-directed RNA polymerase III complex 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral" FBgn0003097 PL(1)sp-S1 Polygenic locus sternopleural S1 http://flybase.net/reports/FBgn0003097.html gene PL(1)sp[S1] 16-Dec-15 2015_12 FBgn0086204 S(ls)6 http://flybase.net/reports/FBgn0086204.html gene 16-Dec-15 2015_12 FBgn0016847 l(1)N27 lethal (1) N27 http://flybase.net/reports/FBgn0016847.html gene N27 16-Dec-15 2015_12 "lethal,recessive" FBgn0086711 mol moladietz http://flybase.net/reports/FBgn0086711.html "FBgn0065471, FBgn0051834, FBgn0040981, FBgn0027871, FBgn0001972, FBgn0028528" protein_coding_gene 0005515=protein binding "0007611=learning or memory, 0015031=protein transport, 0006979=response to oxidative stress, 0008355=olfactory learning, 0007616=long-term memory, 0008105=asymmetric protein localization" "0005886=plasma membrane, 0005789=endoplasmic reticulum membrane, 0045178=basal part of cell, 0016021=integral component of membrane" "lethal 23 in the black-reduced region, l35Bb, lethal (2) 35Bb, lethal 3 in the black-reduced region, B1, l(2)SH1330, moladietz, lethal (2) SH1330, l(2)br3, 35Bb, l(2)SH2 1330, numb-interacting protein, Mol, br3, nip, l(2)35Bb, CG4482, l(2)br23, BG:DS01219.1, NIP, lethal group B1, CG15268" IPR018469=Dual oxidase maturation factor CG4482 16-Dec-15 2015_12 WBGene00015519(C06E1.3) ENSXETG00000023900() "ENSMUSG00000027224(Duoxa1),ENSMUSG00000027225(Duoxa2)" "ENSG00000140254(DUOXA1),ENSG00000140274(DUOXA2)" DRSC01431 IE 1.666347799 -1.6121835 -1.638962866 0.121588718 0.685715965 0.759291439 FBgn0266796 CR45258 http://flybase.net/reports/FBgn0266796.html non_protein_coding_gene CR45258 16-Dec-15 2015_12 FBgn0065086 snmRNA:682 small non-messenger RNA 682 http://flybase.net/reports/FBgn0065086.html non_protein_coding_gene Dm-682 16-Dec-15 2015_12 FBgn0025692 CG3814 http://flybase.net/reports/FBgn0025692.html FBgn0033779 protein_coding_gene 0004972=N-methyl-D-aspartate selective glutamate receptor activity 0017146=N-methyl-D-aspartate selective glutamate receptor complex "CK02213, BEST:CK02213" IPR006214=Bax inhibitor 1-related CG3814 16-Dec-15 2015_12 ENSDARG00000055138(zgc:110410) YNL305C() "WBGene00009580(xbx-6),WBGene00006470(tag-120)" "ENSXETG00000014916(TMBIM1),ENSXETG00000020393(FAIM2)" ENSMUSG00000022564(Grina) ENSG00000178719(GRINA) viable FBgn0052093 tRNA:CR32093 transfer RNA:CR32093 http://flybase.net/reports/FBgn0052093.html FBgn0060100 tRNA_gene 0033427=CAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR32093, tRNA:Q:TTG:AE002602, AE002602.trna4-GlnTTG, chr3L.trna38-GlnTTG" CR32093 16-Dec-15 2015_12 FBgn0263782 Hmgcr HMG Coenzyme A reductase http://flybase.net/reports/FBgn0263782.html "FBgn0010845, FBgn0001205, FBgn0010738, FBgn0024247, FBgn0061415" protein_coding_gene "0004420=hydroxymethylglutaryl-CoA reductase (NADPH) activity, 0050661=NADP binding" "0018990=ecdysis, chitin-based cuticle, 0008354=germ cell migration, 0015936=coenzyme A metabolic process, 0046579=positive regulation of Ras protein signal transduction, 0007280=pole cell migration, 0008299=isoprenoid biosynthetic process, 0055114=oxidation-reduction process, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007626=locomotory behavior, 0035232=germ cell attraction, 0035050=embryonic heart tube development, 0008406=gonad development" "0005789=endoplasmic reticulum membrane, 0016021=integral component of membrane, 0005622=intracellular, 0005778=peroxisomal membrane" "HMGCoAr, HMG-CoA reductase Class I, hmgc, HMGCoARr, l(3)01152, Hmg, HMGCR, HmG-CoAR, hmgcr, Clb, lethal (3) 04684, 3-hydroxy-3-methylglutaryl coenzyme A reductase, DmHMG-CoAr, HMGR, bro1, HMGCoAR, columbus, Hmg-CoA-reductase, unnamed, CG10367, HMGCo-A reductase, hmgrc, BcDNA:LD15354, 3-Hydroxy-3-Methylglutaryl CoA Reductase, l(3)04684, HMG-CoA reductase, HMGCoA reductase, HMGCR_Dm, bs32f05.y1, clb" "IPR000731=Sterol-sensing domain, IPR023074=Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain, IPR004554=Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type, IPR004816=Hydroxymethylglutaryl-CoA reductase, metazoan, IPR023282=Hydroxymethylglutaryl-CoA reductase, N-terminal, IPR009029=Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain, IPR023076=Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site, IPR009023=Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain, IPR002202=Hydroxymethylglutaryl-CoA reductase, class I/II" CG10367 16-Dec-15 2015_12 "ENSDARG00000052728(sltm),ENSDARG00000052734(hmgcra),ENSDARG00000059301(hmgcrb)" "YML075C(HMG1),YLR450W(HMG2)" ENSXETG00000005084(HMGCR) ENSMUSG00000021670(Hmgcr) ENSG00000113161(HMGCR) " embryonic stage , embryonic stage | stage 12-17 , embryonic stage -- adult stage , larval stage&&pupal stage&&adult stage " " embryonic/larval midgut

, ventral midline | restricted

, fat body/gonad primordium

, germline cell | primordium

, parasegment 11 | restricted

, parasegment 12 | restricted

, embryonic/larval foregut

, parasegment 10 | restricted

, dorsal vessel primordium

, embryonic/larval salivary gland

, embryonic/larval hindgut

" DRSC16704 IEK -1.822302564 -2.013714207 -1.792401913 -3.193453556 -1.993892285 -0.286724655 FBgn0263002 CR43310 http://flybase.net/reports/FBgn0263002.html pseudogene_attribute CR43310 16-Dec-15 2015_12 FBgn0050423 CG30423 http://flybase.net/reports/FBgn0050423.html FBgn0064851 protein_coding_gene BcDNA:RH04491 IPR007262=Vacuolar protein sorting 55 CG30423 16-Dec-15 2015_12 "ENSDARG00000071302,ENSDARG00000054969,ENSDARG00000067823" YJR044C(VPS55) WBGene00016244(C30B5.2) "ENSXETG00000025603(LEPROT),ENSXETG00000025792(LEPROTL1)" "ENSMUSG00000035212(Leprot),ENSMUSG00000031513(Leprotl1)" "ENSG00000104660(LEPROTL1),ENSG00000213625(LEPROT)" viable FBgn0065287 l(2)SH2020 lethal (2) SH2020 http://flybase.net/reports/FBgn0065287.html gene l(2)SH2 2020 16-Dec-15 2015_12 "lethal,recessive" FBgn0262252 mir-965 mir-965 stem loop http://flybase.net/reports/FBgn0262252.html miRNA_gene "CR42959, miR-965, 965" CR42959 16-Dec-15 2015_12 "lethal,male,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,wing" FBgn0065956 l(2)SH0057 lethal (2) SH0057 http://flybase.net/reports/FBgn0065956.html gene l(2)SH2 0057 16-Dec-15 2015_12 "lethal,recessive" FBgn0004842 RYa-R RYamide receptor http://flybase.net/reports/FBgn0004842.html "FBgn0044364, FBgn0044365" protein_coding_gene "0004983=neuropeptide Y receptor activity, 0008188=neuropeptide receptor activity, 0001653=peptide receptor activity, 0004930=G-protein coupled receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007166=cell surface receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "PR4, Neuropeptide Y receptor-like, RYamide receptor, CG5811/107368, anon-WO0131005.13, Dm RYa-R, NepYr, anon-WO0131005.15, CG5811, ATR" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR000611=Neuropeptide Y receptor family, IPR017452=GPCR, rhodopsin-like, 7TM" CG5811 16-Dec-15 2015_12 WBGene00022004(Y59H11AL.1) "viable,fertile" FBgn0260020 romeo-y-julieta romeo y julieta http://flybase.net/reports/FBgn0260020.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0027160 l(2)MZ1131 lethal (2) MZ1131 http://flybase.net/reports/FBgn0027160.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265764 CR44571 http://flybase.net/reports/FBgn0265764.html non_protein_coding_gene CR44571 16-Dec-15 2015_12 FBgn0260247 GSd209 http://flybase.net/reports/FBgn0260247.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0038592 CG18599 http://flybase.net/reports/FBgn0038592.html protein_coding_gene 0043565=sequence-specific DNA binding "0006355=regulation of transcription, DNA-templated" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG18599 16-Dec-15 2015_12 "ENSXETG00000023471(HOXC11),ENSXETG00000000732(HOXA11)" FBgn0262976 lawc leg arista wing complex http://flybase.net/reports/FBgn0262976.html "FBgn0001460, FBgn0005688, FBgn0052711, FBgn0063662" protein_coding_gene "0005703=polytene chromosome puff, 0005705=polytene chromosome interband" "leg-arista-wing complex, CG32711, BcDNA:RH09582, l(1)7Ea, lawC, lethal(1)7Ea" CG32711 16-Dec-15 2015_12 FBgn0034481 CG11041 http://flybase.net/reports/FBgn0034481.html protein_coding_gene 0005509=calcium ion binding "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR014837=EF-hand, Ca insensitive" CG11041 16-Dec-15 2015_12 ENSMUSG00000026495(Efcab2) FBgn0037553 CG18249 http://flybase.net/reports/FBgn0037553.html protein_coding_gene CT41336 "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG18249 16-Dec-15 2015_12 viable FBgn0014379 rdgE retinal degeneration E http://flybase.net/reports/FBgn0014379.html gene 16-Dec-15 2015_12 "visual behavior defective,recessive" "retina,ommatidium,rhabdomere,photoreceptor cell" FBgn0263027 CG43322 http://flybase.net/reports/FBgn0263027.html FBgn0031880 protein_coding_gene CG13776 "IPR018961=DnaJ homologue, subfamily C, member 28, conserved domain, IPR001623=DnaJ domain" CG43322 16-Dec-15 2015_12 "viable,fertile" FBgn0264512 CR43911 http://flybase.net/reports/FBgn0264512.html non_protein_coding_gene CR43911 16-Dec-15 2015_12 FBgn0033469 CG12133 http://flybase.net/reports/FBgn0033469.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP15 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG12133 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0039904 Hcf Host cell factor http://flybase.net/reports/FBgn0039904.html FBgn0046383 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0004402=histone acetyltransferase activity, 0003682=chromatin binding, 0003713=transcription coactivator activity" "0016573=histone acetylation, 0043967=histone H4 acetylation, 0043966=histone H3 acetylation, 0051568=histone H3-K4 methylation, 0045927=positive regulation of growth, 0045893=positive regulation of transcription, DNA-templated, 0006338=chromatin remodeling" "0044666=MLL3/4 complex, 0044665=MLL1/2 complex, 0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0048188=Set1C/COMPASS complex, 0005634=nucleus" "FBgn0039904, host cell factor, dHCF, HCF, Host cell factor 1, dHcf1, HCF1, Hcf1, CG1710, HCF_DROME, Heat cell factor, anon-WO0172774.48, dHcf" "IPR015915=Kelch-type beta propeller, IPR006652=Kelch repeat type 1, IPR015916=Galactose oxidase, beta-propeller, IPR013783=Immunoglobulin-like fold, IPR003961=Fibronectin type III" CG1710 16-Dec-15 2015_12 "ENSDARG00000015990(hcfc1a),ENSDARG00000012519(hcfc1b)" "YHR158C(KEL1),YGR238C(KEL2)" WBGene00001827(hcf-1) "ENSMUSG00000020246(Hcfc2),ENSMUSG00000031386(Hcfc1)" "male semi-sterile,female sterile,small body,decreased cell size,increased cell death,partially lethal - majority die,some die during pupal stage,viable,fertile,visible,female limited,lethal,male,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage" "dorsal appendage,egg chamber,wing,ovary,egg,wing disc,wing vein,ectopic,sex comb tooth,humeral bristle,posterior scutellar bristle,female,tergite,anterior compartment,posterior compartment" DRSC17143 K -1.20914844 -0.862377447 -0.220311302 -0.467915374 2.283467786 0.255509094 FBgn0000544 ecl echinus-like http://flybase.net/reports/FBgn0000544.html gene 16-Dec-15 2015_12 FBgn0000817 fs(1)K741 female sterile (1) K741 http://flybase.net/reports/FBgn0000817.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile,heat sensitive" FBgn0267278 CR45714 http://flybase.net/reports/FBgn0267278.html non_protein_coding_gene CR45714 16-Dec-15 2015_12 FBgn0034247 CG6484 http://flybase.net/reports/FBgn0034247.html protein_coding_gene 0005355=glucose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like, IPR003663=Sugar/inositol transporter" CG6484 16-Dec-15 2015_12 "ENSDARG00000020344(slc2a8),ENSDARG00000058731(LOC560602)" "YOL103W(ITR2),YDR497C(ITR1)" viable FBgn0051781 CR31781 http://flybase.net/reports/FBgn0051781.html "FBgn0032616, FBgn0032617, FBgn0061422, FBgn0063119" non_protein_coding_gene 0046331=lateral inhibition "CG31781, CG15132, BcDNA:LP04536, CG15131, BcDNA:GH27691" CR31781 16-Dec-15 2015_12 "viable,visible" chaeta FBgn0030881 CG12985 http://flybase.net/reports/FBgn0030881.html protein_coding_gene IPR007999=Protein of unknown function DUF745 CG12985 16-Dec-15 2015_12 viable DRSC19505 K -0.222199201 0.654048053 -0.034700822 -0.987846451 2.217622675 0.251970327 FBgn0259347 EP-608 http://flybase.net/reports/FBgn0259347.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta,ectopic" FBgn0030671 CG8134 http://flybase.net/reports/FBgn0030671.html protein_coding_gene CG8134 16-Dec-15 2015_12 ENSDARG00000025518(zgc:101679) viable FBgn0027141 l(3)76BCa lethal (3) 76BCa http://flybase.net/reports/FBgn0027141.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0259151 CG42266 http://flybase.net/reports/FBgn0259151.html "FBgn0051737, FBgn0028898, FBgn0051818" protein_coding_gene "CG18115, DS02740.19, CG31737, BG:DS02740.19, CG31818" CG42266 16-Dec-15 2015_12 FBgn0259327 C504 http://flybase.net/reports/FBgn0259327.html gene 16-Dec-15 2015_12 visible "wing,wing margin" FBgn0041258 DyrkH DyrkH http://flybase.net/reports/FBgn0041258.html gene 16-Dec-15 2015_12 FBgn0001094 gau gauze http://flybase.net/reports/FBgn0001094.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0266195 Tgs1 Trimethylguanosine synthase 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0266195.html "FBgn0260241, FBgn0082161, FBgn0051241, FBgn0041570, FBgn0060562" protein_coding_gene "0008173=RNA methyltransferase activity, 0008168=methyltransferase activity" "0001510=RNA methylation, 0008283=cell proliferation, 0009452=7-methylguanosine RNA capping" "lethal (3) S096713, tat-like, Dtl, dtl, DTL, Dromel_CG31241_FBtr0083570_dtl_mORF, DTLd, CG31241, Tat-like, CG44890, l(3)S096713, CG8045, TGS1, 0967/13, tatl, Drosophila Tat-like, Tat like, CT24102, dORF" "IPR019012=RNA cap guanine-N2 methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG44890 16-Dec-15 2015_12 ENSDARG00000067916 WBGene00011631(T08G11.4) ENSMUSG00000028233(Tgs1) FBgn0267209 CR45649 http://flybase.net/reports/FBgn0267209.html non_protein_coding_gene CR45649 16-Dec-15 2015_12 FBgn0020591 anon-57Cf anon-57Cf http://flybase.net/reports/FBgn0020591.html gene unnamed 16-Dec-15 2015_12 FBgn0265145 CR44214 http://flybase.net/reports/FBgn0265145.html non_protein_coding_gene CG44214 CR44214 16-Dec-15 2015_12 FBgn0032053 mRpL51 mitochondrial ribosomal protein L51 http://flybase.net/reports/FBgn0032053.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "MRP-L51, CG13098" "IPR019373=Ribosomal protein L51, mitochondrial" CG13098 16-Dec-15 2015_12 ENSDARG00000041340(zgc:110255) WBGene00011740(T12G3.5) ENSXETG00000022612(TEgg133l14.1) ENSMUSG00000030335(Mrpl51) ENSG00000111639(MRPL51) "viable,visible" trichogen cell DRSC02200 E 0.498324331 -0.576131367 -1.51554978 0.122482273 0.331818201 0.349886873 FBgn0019680 mor(1)11 mortality gene (1)11 http://flybase.net/reports/FBgn0019680.html gene 16-Dec-15 2015_12 short lived FBgn0034548 CG13443 http://flybase.net/reports/FBgn0034548.html protein_coding_gene CG13443 16-Dec-15 2015_12 viable FBgn0060370 l(3)S138006 lethal (3) S138006 http://flybase.net/reports/FBgn0060370.html gene 1380/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0050157 CG30157 http://flybase.net/reports/FBgn0050157.html protein_coding_gene "0016790=thiolester hydrolase activity, 0019783=ubiquitin-like protein-specific protease activity" "IPR012462=Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2" CG30157 16-Dec-15 2015_12 ENSDARG00000061610(zgc:163003) ENSMUSG00000051502(Ufsp1) ENSG00000176125(UFSP1) FBgn0266280 CR44965 http://flybase.net/reports/FBgn0266280.html non_protein_coding_gene CR44965 16-Dec-15 2015_12 FBgn0259174 Nedd4 Nedd4 http://flybase.net/reports/FBgn0259174.html "FBgn0036736, FBgn0052184" protein_coding_gene "0017022=myosin binding, 0061630=ubiquitin protein ligase activity, 0005515=protein binding, 0019904=protein domain specific binding, 0004842=ubiquitin-protein transferase activity" "0007528=neuromuscular junction development, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0007411=axon guidance, 0051965=positive regulation of synapse assembly, 0045807=positive regulation of endocytosis, 0045746=negative regulation of Notch signaling pathway, 0002092=positive regulation of receptor internalization, 0031623=receptor internalization, 0016199=axon midline choice point recognition, 0016567=protein ubiquitination" "0005634=nucleus, 0005737=cytoplasm, 0005886=plasma membrane" "CG7555, dNedd4, dNedd4-1, DNedd4, NEDD4, ACN62428.1, nedd4, CG32184, CG42279" "IPR000569=HECT domain, IPR001202=WW domain, IPR000008=C2 domain" CG42279 16-Dec-15 2015_12 "ENSDARG00000060006,ENSDARG00000039778" YER125W(RSP5) WBGene00022358(Y92H12A.2) "ENSXETG00000021142(Q6DIR6_XENTR),ENSXETG00000016554(NEDD4)" "ENSMUSG00000024589(Nedd4l),ENSMUSG00000032216(Nedd4)" "ENSG00000049759(NEDD4L),ENSG00000069869(NEDD4)" FBgn0019686 lok loki http://flybase.net/reports/FBgn0019686.html protein_coding_gene "0005524=ATP binding, 0050321=tau-protein kinase activity, 0004674=protein serine/threonine kinase activity" "0006282=regulation of DNA repair, 0044773=mitotic DNA damage checkpoint, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0006915=apoptotic process, 0000077=DNA damage checkpoint, 0006974=cellular response to DNA damage stimulus, 0007281=germ cell development, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0006468=protein phosphorylation, 0035234=ectopic germ cell programmed cell death" "0005634=nucleus, 0005737=cytoplasm" "CG10895, Chk2, Dmnk-S, LOKI/CHK2, loki, Dmnk/DChk2, MNK, DmChk2, 38B.4, CHK-2, chk2, Dmnk, maternal nuclear kinase, Dmchk2, Dmnk-L, CHK2, unnamed, chk2/lok, DmCHk2, localized ovarian kinase, checkpoint kinase 2, 10895, chk, Drosophila maternal nuclear kinase, Checkpoint kinase 2, mnk" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000253=Forkhead-associated (FHA) domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008984=SMAD/FHA domain, IPR008271=Serine/threonine-protein kinase, active site" CG10895 16-Dec-15 2015_12 ENSDARG00000025820(chek2) YDL101C(DUN1) "WBGene00011612(T08D2.7),WBGene00000499(chk-2)" ENSXETG00000021608(CHEK2) ENSMUSG00000029521(Chek2) ENSG00000183765(CHEK2) " adult stage && oogenesis stage | stage >=S2 , embryonic stage | stage 1,2 , embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage | stage >=3 " " nurse cell

,

ubiquitous , ovary

, pole cell

" " embryonic stage | stage 3,4 "

ubiquitous "visible,increased cell death,radiation sensitive,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,long lived,viable,chemical resistant,decreased cell death,fertile,cell death defective,conditional" "eye,egg chamber | oogenesis stage S8,egg chamber | oogenesis stage S9,egg chamber,nucleus | embryonic stage,mitosis & nuclear chromosome & embryo,spindle | embryonic stage,wing disc,eye disc,conditional,embryonic/larval neuroblast" FBgn0030809 Ubr1 Ubr1 ubiquitin ligase http://flybase.net/reports/FBgn0030809.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0006368=transcription elongation from RNA polymerase II promoter, 0030163=protein catabolic process" "0000151=ubiquitin ligase complex, 0008023=transcription elongation factor complex" "Ubr1, ubr1, CG9086" "IPR014719=Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like, IPR001841=Zinc finger, RING-type, IPR003769=Adaptor protein ClpS, core, IPR019464=RNA polymerase II elongation factor ELL, N-terminal, IPR003126=Zinc finger, UBR-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG9086 16-Dec-15 2015_12 YGR184C(UBR1) WBGene00016326(C32E8.11) "ENSXETG00000000201(UBR2),ENSXETG00000000961(UBR1)" "ENSMUSG00000023977(Ubr2),ENSMUSG00000027272(Ubr1)" "ENSG00000024048(UBR2),ENSG00000159459(UBR1)" "viable,visible" mesothoracic tergum DRSC20148 I -1.018991161 -2.113807168 -0.814819403 -1.352866079 0.584260609 -0.558454239 FBgn0014061 Su(tor)2-93 Su(tor)2-93 http://flybase.net/reports/FBgn0014061.html gene 16-Dec-15 2015_12 female sterile FBgn0264466 CR43874 http://flybase.net/reports/FBgn0264466.html non_protein_coding_gene CR43874 16-Dec-15 2015_12 FBgn0013693 mt:tRNA:F mitochondrial phenylalanine tRNA http://flybase.net/reports/FBgn0013693.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006307, phenylalanine tRNA, CR34082, tRNA[Phe]" CR34082 16-Dec-15 2015_12 FBgn0038160 CG9759 http://flybase.net/reports/FBgn0038160.html FBgn0063284 protein_coding_gene BcDNA:GH02603 CG9759 16-Dec-15 2015_12 viable DRSC16558 K 0.103064008 0.950675518 0.330907812 0.346222806 1.714206161 0.25546411 FBgn0085391 CG34362 http://flybase.net/reports/FBgn0085391.html "FBgn0063063, FBgn0039570, FBgn0039569" protein_coding_gene "0000166=nucleotide binding, 0003676=nucleic acid binding" "0000381=regulation of alternative mRNA splicing, via spliceosome" "BcDNA:RE10833, CG12870, Tia1-like, CG12872" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG34362 16-Dec-15 2015_12 YNL016W(PUB1) FBgn0082625 S(CycEJP)3.3 S(CycEJP)3.3 http://flybase.net/reports/FBgn0082625.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033378 tsu tsunagi http://flybase.net/reports/FBgn0033378.html protein_coding_gene "0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0000335=negative regulation of transposition, DNA-mediated, 0046595=establishment of pole plasm mRNA localization, 0000226=microtubule cytoskeleton organization, 0007173=epidermal growth factor receptor signaling pathway, 0007294=germarium-derived oocyte fate determination, 0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 0045451=pole plasm oskar mRNA localization, 0007317=regulation of pole plasm oskar mRNA localization, 0007314=oocyte anterior/posterior axis specification, 0006406=mRNA export from nucleus, 0007310=oocyte dorsal/ventral axis specification, 0008380=RNA splicing, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0035145=exon-exon junction complex, 0005634=nucleus, 0005737=cytoplasm" "Tsu, TSU, CG8781, Y14, y14, Y14/Tsunagi, cg8781, Tsunagi" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR008111=RNA-binding motif protein 8, IPR000504=RNA recognition motif domain" CG8781 16-Dec-15 2015_12 ENSDARG00000016516(zgc:110525) WBGene00004387(rnp-4) "ENSMUSG00000038374(Rbm8a),ENSMUSG00000078184(B020018G12Rik)" ENSG00000131795(RBM8A)

"lethal - all die before end of embryonic stage,germline clone,recessive,lethal,some die during embryonic stage,viable,female sterile,cell growth defective,cell lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage" "egg,germline clone,egg chamber,synaptonemal complex | germline clone,germarium region 2b,germarium region 3,dorsal appendage,oocyte nucleus,embryonic/larval brain" FBgn0260596 2L2985 http://flybase.net/reports/FBgn0260596.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0065178 l(3)SH007 lethal (3) SH007 http://flybase.net/reports/FBgn0065178.html gene l(2)SH3 007 16-Dec-15 2015_12 "lethal,recessive" FBgn0024267 acd(2)5E8 auditory courtship defective 5E8 http://flybase.net/reports/FBgn0024267.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0277426 l(3)psg26 http://flybase.net/reports/FBgn0277426.html gene psg26 16-Dec-15 2015_12 FBgn0035003 CG15873 http://flybase.net/reports/FBgn0035003.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH184, SP184" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG15873 16-Dec-15 2015_12 FBgn0264502 CG43901 http://flybase.net/reports/FBgn0264502.html "FBgn0030249, FBgn0030248" protein_coding_gene "CG11203, CG15207" CG43901 16-Dec-15 2015_12 FBgn0085265 CG34236 http://flybase.net/reports/FBgn0085265.html protein_coding_gene CG34236 16-Dec-15 2015_12 FBgn0267698 Pak p21-activated kinase http://flybase.net/reports/FBgn0267698.html "FBgn0014001, FBgn0037437, FBgn0262522" protein_coding_gene "0017124=SH3 domain binding, 0048365=Rac GTPase binding, 0005524=ATP binding, 0017048=Rho GTPase binding, 0004674=protein serine/threonine kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity" "0007480=imaginal disc-derived leg morphogenesis, 0007391=dorsal closure, 0016601=Rac protein signal transduction, 0007155=cell adhesion, 0006468=protein phosphorylation, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007254=JNK cascade, 0007395=dorsal closure, spreading of leading edge cells, 0007411=axon guidance, 0043067=regulation of programmed cell death, 0050803=regulation of synapse structure or activity, 0008360=regulation of cell shape, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0050770=regulation of axonogenesis, 0019991=septate junction assembly" "0031252=cell leading edge, 0005856=cytoskeleton, 0005737=cytoplasm, 0016328=lateral plasma membrane, 0097482=muscle cell postsynaptic density, 0005884=actin filament, 0005925=focal adhesion" "PAK, DPak, p21-activated serine/threonine kinase, PAK2, DmPAK1, PAK kinase, dPAK, p21-activated kinase, Pak kinase, PAK-kinase, psg4, DPAK, dPAK1, p-21 activated kinase, P21-activated kinase, p21-associated kinase, pak, dPak, Dpak1, PaK, Dpak, pak1, lethal (3) persistent salivary gland 4, Pak1, D-Pak, P21-activating kinase, Pak1 kinase, p65[PAK], p21- activated kinase, DPak1, PAK1, dpak1, CG10295, p21 activated kinase, l(3)psg4, dpak" "IPR000719=Protein kinase domain, IPR000095=CRIB domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG10295 16-Dec-15 2015_12 "ENSDARG00000042624(LOC100333149),ENSDARG00000068177(pak2a),ENSDARG00000018476(pak2b)" YOL113W(SKM1) WBGene00003911(pak-1) "ENSXETG00000012421(PAK3),ENSXETG00000011808(pak2),ENSXETG00000010703(PAK1)" "ENSMUSG00000030774(Pak1),ENSMUSG00000031284(Pak3),ENSMUSG00000022781(Pak2)" "ENSG00000180370(PAK2),ENSG00000077264(PAK3),ENSG00000149269(PAK1)" " embryonic stage | stage >=15 , embryonic stage | stage 11-14 , embryonic stage , embryonic stage -- adult stage " " embryonic/larval dorsal vessel

, embryonic central nervous system

, amnioserosa | surrounding

,

ubiquitous , muscle attachment site

" " embryonic stage | late , embryonic stage , embryonic stage | stage 11-14 , embryonic stage | stage >=12 " " embryonic/larval dorsal vessel

,

ubiquitous , amnioserosa | surrounding

, posterior commissure

, muscle attachment site

, embryonic central nervous system

, anterior commissure

, longitudinal connective

" FBgn0266491 SclA Sarcolamban A http://flybase.net/reports/FBgn0266491.html "FBgn0047133, FBgn0045775, FBgn0051696" protein_coding_gene 0055117=regulation of cardiac muscle contraction 0030315=T-tubule "CR31696, BcDNA:RE28911, pncr:003:2L, CG45090, BEST:LP06756, pncr003, pncr003:2L, scl, sarcolamban, mel1, pncr003:2L ORFA, ORF-A" CG45090 16-Dec-15 2015_12 adult heart FBgn0031655 Marcal1 Marcal1 http://flybase.net/reports/FBgn0031655.html protein_coding_gene "1990163=ATP-dependent four-way junction helicase activity, 0005524=ATP binding, 0036310=annealing helicase activity, 0008094=DNA-dependent ATPase activity" "0006259=DNA metabolic process, 0036292=DNA rewinding, 0071932=replication fork reversal, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005705=polytene chromosome interband" "hepA-related protein, dmHARP, dsmarcal1, Marca1, HARP, CG3753" "IPR000330=SNF2-related, N-terminal domain, IPR001650=Helicase, C-terminal, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR010003=HARP domain" CG3753 16-Dec-15 2015_12 WBGene00015806(C16A3.1) ENSXETG00000000465(SMARCAL1) ENSMUSG00000039354(Smarcal1) ENSG00000138375(SMARCAL1) "short lived,heat sensitive,visible,viable" "egg,heat sensitive,wing vein,ectopic,trichogen cell" FBgn0085571 CG41245 http://flybase.net/reports/FBgn0085571.html FBan0041245 protein_coding_gene 16-Dec-15 2015_12 FBgn0022806 E(var)19 E(var)19 http://flybase.net/reports/FBgn0022806.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0260392 CG42518 http://flybase.net/reports/FBgn0260392.html "FBan0005134, FBgn0034311" protein_coding_gene 0016592=mediator complex "CG5134, Mediator complex subunit 9" CG42518 16-Dec-15 2015_12 FBgn0034728 rad50 rad50 http://flybase.net/reports/FBgn0034728.html protein_coding_gene 0016887=ATPase activity "0006974=cellular response to DNA damage stimulus, 0002168=instar larval development, 0016233=telomere capping, 0006302=double-strand break repair, 0000723=telomere maintenance, 0051276=chromosome organization, 0006281=DNA repair" "0005634=nucleus, 0030870=Mre11 complex" "Dmrad50, CG6339, 6339, Rad50, RAD50" "IPR013134=RAD50, zinc hook, IPR004584=DNA repair protein Rad50, eukaryotes, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6339 16-Dec-15 2015_12 ENSDARG00000038917 YNL250W(RAD50) WBGene00004296(rad-50) ENSMUSG00000020380(Rad50) ENSG00000113522(RAD50) "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,radiation sensitive,viable" "wing margin,mitosis & nuclear chromosomeX58-8),chromosome, telomeric regionX58-8),eye,wing,chaeta,wing disc,mitosis & nuclear chromosome,chromosome, telomeric region,condensed chromosome" FBgn0025557 anon-88Ba anon-88Ba http://flybase.net/reports/FBgn0025557.html gene c3.5/c4.4 16-Dec-15 2015_12 FBgn0023515 CG14814 http://flybase.net/reports/FBgn0023515.html protein_coding_gene EG:63B12.6 IPR006640=SprT-like CG14814 16-Dec-15 2015_12 ENSDARG00000057716(zgc:113346) "viable,fertile,lethal" FBgn0027588 GCS2ë± Glucosidase 2 ë± subunit http://flybase.net/reports/FBgn0027588.html protein_coding_gene "0030246=carbohydrate binding, 0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process "0005875=microtubule associated complex, 0017177=glucosidase II complex, 0005576=extracellular region, 0012505=endomembrane system" "Glucosidase 2 alpha subunit, alpha-glucosidase, clot#312, CG14476, glucosidase II, BcDNA:GH04962, GCS2alpha" "IPR017853=Glycoside hydrolase superfamily, IPR011013=Galactose mutarotase-like domain, IPR000322=Glycoside hydrolase family 31, IPR025887=Glycoside hydrolase family 31, N-terminal domain" CG14476 16-Dec-15 2015_12 YBR229C(ROT2) "WBGene00018682(aagr-4),WBGene00009583(aagr-3)" "ENSXETG00000005580(GANAB),ENSXETG00000000302(GANC)" "ENSMUSG00000071650(Ganab),ENSMUSG00000062646(Ganc)" "ENSG00000089597(GANAB),ENSG00000214013(GANC)" "partially lethal - majority die,some die during pupal stage" FBgn0053764 CG33764 http://flybase.net/reports/FBgn0053764.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33764 16-Dec-15 2015_12 FBgn0051779 Acp24A4 Accessory gland protein 24A4 http://flybase.net/reports/FBgn0051779.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "Acp24A4, CG31779" "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG31779 16-Dec-15 2015_12 ENSDARG00000069736 ENSXETG00000016886(SPINT3) "ENSMUSG00000074595(Wfdc6a),ENSMUSG00000070531(Wfdc6b),ENSMUSG00000017733(Spinlw1)" viable DRSC22352 K -0.077597493 0.1092658 0.384336365 0.05940326 2.152043177 -0.185223184 FBgn0024908 anon-99Fa anon-99Fa http://flybase.net/reports/FBgn0024908.html gene K7 16-Dec-15 2015_12 FBgn0085366 CG34337 http://flybase.net/reports/FBgn0085366.html protein_coding_gene CG34337 16-Dec-15 2015_12 FBgn0017465 TfIIH-29 Transcription factor IIH-29kD http://flybase.net/reports/FBgn0017465.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TFIIH, TfIIH" 16-Dec-15 2015_12 FBgn0053665 CG33665 http://flybase.net/reports/FBgn0053665.html protein_coding_gene CG33665 16-Dec-15 2015_12 FBgn0053681 CG33681 http://flybase.net/reports/FBgn0053681.html FBgn0028907 protein_coding_gene "DS01514.3, BG:DS01514.3" 16-Dec-15 2015_12 FBgn0043388 EP383 EP383 http://flybase.net/reports/FBgn0043388.html gene EP0383 16-Dec-15 2015_12 visible "scutellar bristle,trichogen cell,tormogen cell,embryonic/larval salivary gland" FBgn0031135 CR11235 http://flybase.net/reports/FBgn0031135.html pseudogene_attribute CG11235 CR11235 16-Dec-15 2015_12 viable FBgn0003661 syndrome syndrome http://flybase.net/reports/FBgn0003661.html gene syn 16-Dec-15 2015_12 "female sterile,male sterile,viable,reduced" FBgn0050196 CG30196 http://flybase.net/reports/FBgn0050196.html FBgn0034757 protein_coding_gene CG13514 IPR006629=LPS-induced tumour necrosis factor alpha factor CG30196 16-Dec-15 2015_12 viable FBgn0036364 CG14109 http://flybase.net/reports/FBgn0036364.html protein_coding_gene CG14109 16-Dec-15 2015_12 viable FBgn0065691 l(2)SH0643 lethal (2) SH0643 http://flybase.net/reports/FBgn0065691.html gene l(2)SH2 0643 16-Dec-15 2015_12 "lethal,recessive" FBgn0010021 E(Dl)9P39.8 Enhancer of Delta 9P39.8 http://flybase.net/reports/FBgn0010021.html gene 16-Dec-15 2015_12 FBgn0003441 smk smoky http://flybase.net/reports/FBgn0003441.html gene sm 16-Dec-15 2015_12 "viable,good,visible,recessive,female sterile,heat sensitive,body color defective" adult thorax FBgn0262697 Su(VGlut)B37 http://flybase.net/reports/FBgn0262697.html gene B37 16-Dec-15 2015_12 FBgn0044006 Su(rst)C103 Su(rst)C103 http://flybase.net/reports/FBgn0044006.html gene 0001745=compound eye morphogenesis C103 16-Dec-15 2015_12 viable eye FBgn0000271 ccw concave wing http://flybase.net/reports/FBgn0000271.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile" wing FBgn0037065 CG12974 http://flybase.net/reports/FBgn0037065.html protein_coding_gene CG12974 16-Dec-15 2015_12 FBgn0028198 l(3)S020514a lethal (3) S020514a http://flybase.net/reports/FBgn0028198.html gene "l(3)S020514, 0205/14" 16-Dec-15 2015_12 "lethal,recessive" FBgn0266743 CR45216 http://flybase.net/reports/FBgn0266743.html non_protein_coding_gene CR45216 16-Dec-15 2015_12 FBgn0005179 l(2)S1A lethal of Seto 1A http://flybase.net/reports/FBgn0005179.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "adult garland cell,pupa" FBgn0062249 Tel Telomere elongation http://flybase.net/reports/FBgn0062249.html gene 0000723=telomere maintenance Gaiano strain 16-Dec-15 2015_12 "viable,fertile" "polytene chromosome, telomeric region" FBgn0015869 anon-37Ca anon-37Ca http://flybase.net/reports/FBgn0015869.html gene transcription unit No. 5 16-Dec-15 2015_12 FBgn0017388 l(1)15Dc lethal (1) 15Dc http://flybase.net/reports/FBgn0017388.html gene 16-Dec-15 2015_12 lethal FBgn0085810 CR41597 http://flybase.net/reports/FBgn0085810.html FBan0041597 pseudogene_attribute CR41597 16-Dec-15 2015_12 FBgn0262427 mir-1016 mir-1016 stem loop http://flybase.net/reports/FBgn0262427.html "FBgn0250812, FBgn0262274" miRNA_gene "mir-1010, CR42981, dme-mir-1016, miR-1016" CR42981 16-Dec-15 2015_12 viable FBgn0000590 e(sei) enhancer of seizure http://flybase.net/reports/FBgn0000590.html gene "0007638=mechanosensory behavior, 0009612=response to mechanical stimulus" 16-Dec-15 2015_12 "bang sensitive,recessive,hyperactive,uncoordinated" FBgn0026604 Act88F::Scer\ACT1 Act88F::Scer\act1 http://flybase.net/reports/FBgn0026604.html engineered_fusion_gene Act88F::Scer\act1 16-Dec-15 2015_12 FBgn0000713 fm fine macros http://flybase.net/reports/FBgn0000713.html gene 16-Dec-15 2015_12 "partially lethal - majority live,visible,male fertile,viable,male,reduced" "abdomen,macrochaeta,adult abdomen" FBgn0032631 CG15140 http://flybase.net/reports/FBgn0032631.html protein_coding_gene CG15140 16-Dec-15 2015_12 FBgn0003745 trd tridenticle http://flybase.net/reports/FBgn0003745.html gene 16-Dec-15 2015_12 denticle FBgn0000895 fs(1)M95 female sterile (1) M95 http://flybase.net/reports/FBgn0000895.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0030655 CG9213 http://flybase.net/reports/FBgn0030655.html FBgn0052585 protein_coding_gene 0003824=catalytic activity CG32585 "IPR006768=Cwf19-like, C-terminal domain-1, IPR011146=HIT-like domain, IPR006767=Cwf19-like protein, C-terminal domain-2" CG9213 16-Dec-15 2015_12 WBGene00015156(B0361.2) ENSXETG00000018483(cwf19l2) ENSMUSG00000025898(Cwf19l2) ENSG00000152404(CWF19L2) FBgn0028190 l(3)S023426 lethal (3) S023426 http://flybase.net/reports/FBgn0028190.html gene 0234/26 16-Dec-15 2015_12 "lethal,recessive" FBgn0083252 E(smoDN)G Enhancer of smoDN group G http://flybase.net/reports/FBgn0083252.html gene 0007224=smoothened signaling pathway Group G 16-Dec-15 2015_12 "visible,recessive,somatic clone,lethal" "eye,somatic clone,eye photoreceptor cell,ommatidium,wing,wing margin" FBgn0031703 CG12512 http://flybase.net/reports/FBgn0031703.html protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity 0008152=metabolic process "0005777=peroxisome, 0005875=microtubule associated complex" "IPR020845=AMP-binding, conserved site, IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase" CG12512 16-Dec-15 2015_12 ENSDARG00000061201(acsf2) "WBGene00018488(acs-1),WBGene00009221(acs-2)" ENSXETG00000006826(ACSF2) "ENSMUSG00000076435(Acsf2),ENSMUSG00000048916" ENSG00000167107(ACSF2) FBgn0040155 l(1)G0464 lethal (1) G0464 http://flybase.net/reports/FBgn0040155.html gene 16-Dec-15 2015_12 "lethal,recessive,female sterile" FBgn0031061 CG14232 http://flybase.net/reports/FBgn0031061.html FBgn0019900 protein_coding_gene 0000062=fatty-acyl-CoA binding 0006810=transport 0016021=integral component of membrane anon-18DEc "IPR000582=Acyl-CoA-binding protein, ACBP, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR009038=GOLD domain" CG14232 16-Dec-15 2015_12 "ENSDARG00000042623,ENSDARG00000024602(zgc:162964)" WBGene00012765(Y41E3.7) ENSXETG00000022634(ACBD3) ENSMUSG00000026499(Acbd3) ENSG00000182827(ACBD3) viable DRSC19588 K 0.797774322 0.643074076 0.684747928 0.5123716 -1.786143599 -1.16657451 FBgn0000712 flz filzig http://flybase.net/reports/FBgn0000712.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" "denticle belt,trichome,mouth hooks,denticle,microchaeta,cephalopharyngeal skeleton" FBgn0065987 iab-3-2.s iab-3-2.s http://flybase.net/reports/FBgn0065987.html gene 3-2 s 16-Dec-15 2015_12 FBgn0046841 ird27 immune response deficient 27 http://flybase.net/reports/FBgn0046841.html gene 0006959=humoral immune response 16-Dec-15 2015_12 "lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0265722 CR44529 http://flybase.net/reports/FBgn0265722.html non_protein_coding_gene "lincRNA.431, incRNA.431" CR44529 16-Dec-15 2015_12 FBgn0030990 CG7556 http://flybase.net/reports/FBgn0030990.html protein_coding_gene 0003677=DNA binding 0012505=endomembrane system "IPR018253=DnaJ domain, conserved site, IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like, IPR001623=DnaJ domain, IPR017884=SANT domain, IPR017877=Myb-like domain" CG7556 16-Dec-15 2015_12 ENSDARG00000001940(zgc:152779) WBGene00018836(F54F2.9) ENSXETG00000007390(dnajc1) ENSMUSG00000026740(Dnajc1) ENSG00000136770(DNAJC1) viable DRSC20052 IE 1.196139461 4.589133366 1.110456873 -2.87731758 -0.160399198 -0.467875709 FBgn0000797 fs(1)de8 female sterile (1) defective eggs 8 http://flybase.net/reports/FBgn0000797.html gene de8 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion" FBgn0053303 CG33303 http://flybase.net/reports/FBgn0053303.html FBgn0032232 protein_coding_gene 0004579=dolichyl-diphosphooligosaccharide-protein glycotransferase activity 0006486=protein glycosylation "0016021=integral component of membrane, 0012505=endomembrane system, 0008250=oligosaccharyltransferase complex" "CG5364, OST" IPR007676=Ribophorin I CG33303 16-Dec-15 2015_12 ENSDARG00000059323(rpn1) YJL002C(OST1) WBGene00020683(T22D1.4) ENSXETG00000016175(rpn1) ENSMUSG00000030062(Rpn1) ENSG00000163902(RPN1) FBgn0028913 CG3473 http://flybase.net/reports/FBgn0028913.html FBgn0063328 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0016567=protein ubiquitination 0000151=ubiquitin ligase complex "cg3473, BcDNA:AT16033, BG:DS01486.1" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2, IPR023313=Ubiquitin-conjugating enzyme, active site" CG3473 16-Dec-15 2015_12 YDR092W(UBC13) ENSMUSG00000074781(Ube2n) viable FBgn0061122 l(3)S004209a lethal (3) S004209a http://flybase.net/reports/FBgn0061122.html gene 0042/09 16-Dec-15 2015_12 lethal FBgn0065534 l(2)SH1091 lethal (2) SH1091 http://flybase.net/reports/FBgn0065534.html gene l(2)SH2 1091 16-Dec-15 2015_12 "lethal,recessive" FBgn0002387 l(3)93Dc lethal (3) 93Dc http://flybase.net/reports/FBgn0002387.html gene "l(3)er11, er11" 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0000371 crib cribble http://flybase.net/reports/FBgn0000371.html gene 0007349=cellularization 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0065316 l(2)SH1927 lethal (2) SH1927 http://flybase.net/reports/FBgn0065316.html gene l(2)SH2 1927 16-Dec-15 2015_12 "lethal,recessive" FBgn0032339 CG4705 http://flybase.net/reports/FBgn0032339.html protein_coding_gene 0035859=Seh1-associated complex "SEA3, FBtr0080196" "IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR006575=RWD domain" CG4705 16-Dec-15 2015_12 YDR128W(MTC5) ENSXETG00000007677(WDR59) ENSMUSG00000031959(Wdr59) ENSG00000103091(WDR59) viable FBgn0004698 Xpc "Xeroderma pigmentosum, complementation group C" http://flybase.net/reports/FBgn0004698.html "FBgn0002896, FBgn0002898, FBgn0010427" protein_coding_gene 0003684=damaged DNA binding "0010777=meiotic mismatch repair involved in reciprocal meiotic recombination, 0006289=nucleotide-excision repair" 0005634=nucleus "CG8153, mus(2)201[GI], mus210, Mus210, Xeroderma pigmentosum group C-like, XPC[DM], mus(2)201G1, DhXPC, mus201[G1], Xpcc, DmXPC, mus(2)201, DhR4, mutagen-sensitive 210, mus212, Mus 210, xeroderma pigmentosum group C complementing factor" "IPR004583=DNA repair protein Rad4, IPR018327=Rad4 beta-hairpin domain 2, IPR018328=Rad4 beta-hairpin domain 3, IPR018026=DNA repair protein Rad4, subgroup, IPR018326=Rad4 beta-hairpin domain 1, IPR018325=Rad4/PNGase transglutaminase-like fold" CG8153 16-Dec-15 2015_12 ENSDARG00000039754(xpc) YER162C(RAD4) WBGene00022296(xpc-1) ENSMUSG00000030094(Xpc) ENSG00000154767(XPC) "viable,chemical sensitive,recessive,DNA repair defective,fertile,maternal effect" FBgn0011184 l(1)294-27 lethal (1) 294-27 http://flybase.net/reports/FBgn0011184.html FBgn0010200 gene 294-27 16-Dec-15 2015_12 "lethal,recessive" FBgn0028690 Rpn5 Regulatory particle non-ATPase 5 http://flybase.net/reports/FBgn0028690.html protein_coding_gene 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0005838=proteasome regulatory particle, 0008541=proteasome regulatory particle, lid subcomplex, 0000502=proteasome complex" "p55, CG1100, rpn5, Rpn5" "IPR000717=Proteasome component (PCI) domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG1100 16-Dec-15 2015_12 ENSDARG00000052377(psmd12) YDL147W(RPN5) WBGene00004461(rpn-5) ENSXETG00000001584(psmd12) ENSMUSG00000020720(Psmd12) ENSG00000197170(PSMD12) "lethal,partially lethal - majority die" DRSC28279 IK -2.35352585 -2.796241163 -1.328969724 -0.174825084 1.224998235 1.89839424 FBgn0011180 l(1)291-95 lethal (1) 291-95 http://flybase.net/reports/FBgn0011180.html FBgn0010199 gene 291-95 16-Dec-15 2015_12 "lethal,recessive" FBgn0260474 CG30002 http://flybase.net/reports/FBgn0260474.html FBgn0050002 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG30002 16-Dec-15 2015_12 viable FBgn0260337 GSd057 http://flybase.net/reports/FBgn0260337.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0069324 X-157-3 X-157-3 http://flybase.net/reports/FBgn0069324.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "extended germ band embryo,germline clone,maternal effect" FBgn0014109 anon-73B anon-73B http://flybase.net/reports/FBgn0014109.html gene "TU10, transcription unit 10" 16-Dec-15 2015_12 " egg stage | unfertilized egg , adult stage , embryonic stage " unfertilized egg

FBgn0015448 l(1)9BDa lethal (1) 9BDa http://flybase.net/reports/FBgn0015448.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,visible" wing FBgn0030855 CG5800 http://flybase.net/reports/FBgn0030855.html protein_coding_gene "0003676=nucleic acid binding, 0003724=RNA helicase activity, 0005524=ATP binding" "0007526=larval somatic muscle development, 0022008=neurogenesis" "DmRH14, cg5800" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR025313=Domain of unknown function DUF4217" CG5800 16-Dec-15 2015_12 ENSDARG00000061865 YJL033W(HCA4) WBGene00021277(Y23H5B.6) ENSXETG00000014458(ddx10) ENSMUSG00000053289(Ddx10) ENSG00000178105(DDX10) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,embryonic/larval neuroblast,ganglion mother cell" FBgn0261985 Ptpmeg Protein tyrosine phosphatase Meg http://flybase.net/reports/FBgn0261985.html "FBgn0035133, FBgn0062170, FBgn0046703" protein_coding_gene "0008092=cytoskeletal protein binding, 0004725=protein tyrosine phosphatase activity" "0048036=central complex development, 0006470=protein dephosphorylation, 0040040=thermosensory behavior, 0016319=mushroom body development, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0048846=axon extension involved in axon guidance" "0005829=cytosol, 0005737=cytoplasm, 0005739=mitochondrion, 0005856=cytoskeleton" "CG1228, ptpmeg, MEG1, PTP-meg, dPtpmeg, anon-WO0118547.211, Ptpmeg, ptmpeg, scc, Meg, split central complex, dMEG1" "IPR018980=FERM, C-terminal PH-like domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000242=PTP type protein phosphatase, IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR001478=PDZ domain, IPR000299=FERM domain, IPR016130=Protein-tyrosine phosphatase, active site, IPR014847=FERM adjacent (FA), IPR012151=Protein-tyrosine phosphatase, non-receptor type-3, -4, IPR018979=FERM, N-terminal, IPR029071=Ubiquitin-related domain, IPR029021=Protein-tyrosine phosphatase-like, IPR019747=FERM conserved site" CG1228 16-Dec-15 2015_12 "ENSDARG00000000183(si:rp71-1n18.2),ENSDARG00000039187(epb41l5),ENSDARG00000000631(LOC407644),ENSDARG00000055784" WBGene00004213(ptp-1) "ENSXETG00000024183(PTPN4),ENSXETG00000003648(PTPN3)" "ENSMUSG00000026384(Ptpn4),ENSMUSG00000038764(Ptpn3)" "ENSG00000088179(PTPN4),ENSG00000070159(PTPN3)" DRSC08684 E 0.525507356 0.652815625 1.366287425 -1.518372638 0.506570183 -0.256805308 FBgn0262807 CG43178 http://flybase.net/reports/FBgn0262807.html protein_coding_gene MIP03715_ORF_2 CG43178 16-Dec-15 2015_12 FBgn0032470 CG5142 http://flybase.net/reports/FBgn0032470.html protein_coding_gene 0005215=transporter activity "0018095=protein polyglutamylation, 0042384=cilium assembly, 0042073=intraciliary transport" "0005879=axonemal microtubule, 0005929=cilium, 0030992=intraciliary transport particle B" TTC30 "IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain" CG5142 16-Dec-15 2015_12 ENSDARG00000038024(flr) WBGene00001117(dyf-1) ENSXETG00000008469() "ENSMUSG00000075273(Ttc30b),ENSMUSG00000075272(Ttc30a2),ENSMUSG00000075271(Ttc30a1)" "ENSG00000197557(TTC30A),ENSG00000196659(TTC30B)" viable DRSC02818 E 1.006394616 0.731902914 0.121282927 2.099690979 -0.296071661 0.167314647 FBgn0002588 M(1)13A Minute (1) 13A http://flybase.net/reports/FBgn0002588.html gene 16-Dec-15 2015_12 FBgn0030290 CG11756 http://flybase.net/reports/FBgn0030290.html FBgn0063355 protein_coding_gene BcDNA:AT06648 CG11756 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0005140 l(2)B lethal (2) B http://flybase.net/reports/FBgn0005140.html gene 16-Dec-15 2015_12 lethal FBgn0014166 fs(1)18Da fs(1)18Da http://flybase.net/reports/FBgn0014166.html gene unnamed 16-Dec-15 2015_12 "egg chamber,follicle cell" FBgn0064141 sl(2)AG2 sl(2)AG2 http://flybase.net/reports/FBgn0064141.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0001775 l(1)M53 lethal (1) M53 http://flybase.net/reports/FBgn0001775.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0034622 CG15666 http://flybase.net/reports/FBgn0034622.html FBgn0062916 protein_coding_gene 0042384=cilium assembly 0034464=BBSome "BBS9, BcDNA:RH67628" "IPR028074=PTHB1, C-terminal domain, IPR028073=PTHB1, N-terminal domain, IPR026511=Parathyroid hormone-responsive B1" CG15666 16-Dec-15 2015_12 WBGene00016744(bbs-9) ENSXETG00000021125(BBS9) ENSMUSG00000035919(Bbs9) ENSG00000122507(BBS9) viable FBgn0038766 CG4854 http://flybase.net/reports/FBgn0038766.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG4854 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "ENSMUSG00000046792(Zfp787),ENSMUSG00000054716(Zfp771),ENSMUSG00000042097(Zfp239)" "viable,fertile" FBgn0010459 l(2)00248 lethal (2) 00248 http://flybase.net/reports/FBgn0010459.html gene "l(2)248, 0248" 16-Dec-15 2015_12 "lethal,recessive" FBgn0016645 ER3-3 ER3-3 http://flybase.net/reports/FBgn0016645.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031702 fusl fuseless http://flybase.net/reports/FBgn0031702.html protein_coding_gene "0070073=clustering of voltage-gated calcium channels, 0007274=neuromuscular synaptic transmission, 0007270=neuron-neuron synaptic transmission" "0042734=presynaptic membrane, 0043195=terminal bouton, 0005886=plasma membrane" CG14021 CG14021 16-Dec-15 2015_12 "neurophysiology defective,locomotor behavior defective,viable" "retina,embryonic/larval neuromuscular junction,synaptic vesicle" FBgn0028136 l(3)S049405a lethal (3) S049405a http://flybase.net/reports/FBgn0028136.html gene "l(3)S049405, 0494/05" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0060601 l(3)S091801b lethal (3) S091801b http://flybase.net/reports/FBgn0060601.html gene 0918/01 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0022959 yps ypsilon schachtel http://flybase.net/reports/FBgn0022959.html protein_coding_gene "0003729=mRNA binding, 0003677=DNA binding, 0003676=nucleic acid binding" "0006355=regulation of transcription, DNA-templated, 0048477=oogenesis, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005634=nucleus, 0071013=catalytic step 2 spliceosome" "YPS, Ypsilon schachtel, Yps, p57, Ypsilon Schactel, Ypsilon Schachtel, p45, CG5654" "IPR011129=Cold shock protein, IPR002059=Cold-shock protein, DNA-binding, IPR019844=Cold-shock conserved site, IPR012340=Nucleic acid-binding, OB-fold" CG5654 16-Dec-15 2015_12 ENSDARG00000004757(ybx1) WBGene00000472(cey-1) "ENSXETG00000013436(nsep1),ENSXETG00000016239(BC090361.1)" "ENSMUSG00000028639(Ybx1),ENSMUSG00000030189(Csda),ENSMUSG00000018554(Ybx2)" "ENSG00000065978(YBX1),ENSG00000060138(CSDA),ENSG00000006047(YBX2)" "lethal,viable,female fertile,fertile" FBgn0029816 CG12729 http://flybase.net/reports/FBgn0029816.html protein_coding_gene "IPR021625=PI31 proteasome regulator, N-terminal" CG12729 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0038891 CG15499 http://flybase.net/reports/FBgn0038891.html protein_coding_gene CR43372 16-Dec-15 2015_12 FBgn0023220 E(lz)174 E(lz)174 http://flybase.net/reports/FBgn0023220.html gene 16-Dec-15 2015_12 wild-type FBgn0015456 l(2)37CDa lethal (2) 37CDa http://flybase.net/reports/FBgn0015456.html gene "l(2)E142,M" 16-Dec-15 2015_12 "lethal,recessive" FBgn0259462 EP-469.1 http://flybase.net/reports/FBgn0259462.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0069217 gl(3R)66-35 gl(3R)66-35 http://flybase.net/reports/FBgn0069217.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "dorsal appendage,germline clone,maternal effect,embryonic head,embryonic segment" FBgn0011796 l(3)j7A6 lethal (3) j7A6 http://flybase.net/reports/FBgn0011796.html gene l(3j7A6 16-Dec-15 2015_12 "lethal,recessive" FBgn0030748 Traf-like TNF-receptor-associated factor-like http://flybase.net/reports/FBgn0030748.html protein_coding_gene "0007165=signal transduction, 0006952=defense response" 0005737=cytoplasm "CG4394, Traf3, dTRAF3, Traf-related, TRAF3" "IPR008974=TRAF-like, IPR002083=MATH/TRAF domain" CG4394 16-Dec-15 2015_12 viable FBgn0040225 en::osa en::osa http://flybase.net/reports/FBgn0040225.html engineered_fusion_gene 16-Dec-15 2015_12 visible "macrochaeta,ectopic,microchaeta,wing margin bristle,wing vein" FBgn0039126 CG13601 http://flybase.net/reports/FBgn0039126.html protein_coding_gene IPR010754=Optic atrophy 3-like CG13601 16-Dec-15 2015_12 ENSDARG00000061761(opa3) WBGene00019274(H43I07.1) ENSXETG00000018240(OPA3) ENSMUSG00000052214(Opa3) ENSG00000125741(OPA3) viable DRSC14604 IE 1.580760816 0.087020579 3.374129783 0.263582245 0.748009906 -0.599075529 FBgn0260116 2L4155 http://flybase.net/reports/FBgn0260116.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0027177 l(2)60Ag lethal (2) 60Ag http://flybase.net/reports/FBgn0027177.html gene "unnamed, Unassigned in Interval 2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267523 5.8SrRNA-ë¬:CR45863 5.8S ribosomal RNA pseudogene:CR45863 http://flybase.net/reports/FBgn0267523.html pseudogene_attribute CR45863 CR45863 16-Dec-15 2015_12 FBgn0082616 S(CycEJP)E9S1 S(CycEJP)E9S1 http://flybase.net/reports/FBgn0082616.html gene E9S1 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0031356 CG17660 http://flybase.net/reports/FBgn0031356.html protein_coding_gene 0016021=integral component of membrane "IPR009637=Transmembrane receptor, eukaryota" CG17660 16-Dec-15 2015_12 ENSDARG00000052607 "YKL039W(PTM1),YHL017W()" WBGene00016867(C52B9.4) ENSXETG00000013776(TGas047b06.1) "ENSMUSG00000014353(Tmem87b),ENSMUSG00000033808(Tmem87a)" "ENSG00000103978(TMEM87A),ENSG00000153214(TMEM87B)" viable FBgn0000770 fs(1)A1074 female sterile (1) A1074 http://flybase.net/reports/FBgn0000770.html gene 16-Dec-15 2015_12 "lethal,rescuable maternal effect,heat sensitive,female sterile,recessive" FBgn0267922 CR46203 http://flybase.net/reports/FBgn0267922.html non_protein_coding_gene lincRNA.756 CR46203 16-Dec-15 2015_12 FBgn0039530 Tusp Tusp http://flybase.net/reports/FBgn0039530.html protein_coding_gene 0035556=intracellular signal transduction "CG5586, TUSP, DMG2-MB6.chr3R.24.043, dmWSBa Tubby-like" "IPR000007=Tubby, C-terminal, IPR025659=Tubby C-terminal-like domain, IPR017986=WD40-repeat-containing domain, IPR001496=SOCS box domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG5586 16-Dec-15 2015_12 "ENSDARG00000063056(LOC562633),ENSDARG00000045911(si:ch211-51e12.5)" WBGene00022139(tub-2) ENSMUSG00000034377(Tulp4) ENSG00000130338(TULP4) viable FBgn0027198 l(2)2B lethal (2) 2B http://flybase.net/reports/FBgn0027198.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0027114 mei-P38 mei-P38 http://flybase.net/reports/FBgn0027114.html gene 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0267976 Tim23 Translocase of inner mitochondrial membrane 23 http://flybase.net/reports/FBgn0267976.html "FBgn0063893, FBgn0043839, FBgn0062865, FBan0040042, FBgn0058042" protein_coding_gene "CG40042, Tim23, unnamed, BEST:GH02609, LP07554, BcDNA:SD19278" IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG40042 16-Dec-15 2015_12 "ENSDARG00000071396(timm23),ENSDARG00000058802" YNR017W(TIM23) WBGene00008857(F15D3.7) ENSXETG00000026175(timm23) "ENSMUSG00000069622(Gm10273),ENSMUSG00000013701(Timm23)" "ENSG00000138297(TIMM23),ENSG00000204152(TIMM23B)" FBgn0024928 Su(var)2-b701 Su(var)2-b701 http://flybase.net/reports/FBgn0024928.html gene Su-var(2)b701 16-Dec-15 2015_12 FBgn0044513 l(3)80Fe lethal (3) 80Fe http://flybase.net/reports/FBgn0044513.html gene "80Fe, l5A, l(3)Lh5" 16-Dec-15 2015_12 lethal FBgn0043783 CG32444 http://flybase.net/reports/FBgn0043783.html "FBgn0037111, FBgn0037112, FBgn0052444, FBgn0063607" protein_coding_gene "0030246=carbohydrate binding, 0004034=aldose 1-epimerase activity" 0019318=hexose metabolic process "aldose 1-epimerase, BcDNA:GH08902, CG12562, CT3430, CG14576" "IPR011013=Galactose mutarotase-like domain, IPR014718=Glycoside hydrolase-type carbohydrate-binding, subgroup, IPR008183=Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR015443=Aldose 1-epimerase" CG32444 16-Dec-15 2015_12 ENSDARG00000057630(galm) "YHR210C(),YNR071C()" WBGene00015270(C01B4.6) ENSXETG00000009022(GALM) ENSMUSG00000035473(Galm) ENSG00000143891(GALM) "viable,fertile" FBgn0266877 CR45338 http://flybase.net/reports/FBgn0266877.html non_protein_coding_gene CR45338 16-Dec-15 2015_12 FBgn0264369 CR43821 http://flybase.net/reports/FBgn0264369.html non_protein_coding_gene CR43821 16-Dec-15 2015_12 FBgn0003303 rv raven http://flybase.net/reports/FBgn0003303.html gene 16-Dec-15 2015_12 "visible,recessive,female sterile,viable,male,reduced,male fertile,female,poor,eye color defective" "pigment cell,wing" FBgn0265087 CR44198 http://flybase.net/reports/FBgn0265087.html non_protein_coding_gene lincRNA.126 CR44198 16-Dec-15 2015_12 FBgn0065886 l(2)SH0227 lethal (2) SH0227 http://flybase.net/reports/FBgn0065886.html gene l(2)SH2 0227 16-Dec-15 2015_12 "lethal,recessive" FBgn0022759 Wmc3 Wee-Mik-Complementing 3 http://flybase.net/reports/FBgn0022759.html gene WMC3 16-Dec-15 2015_12 FBgn0029173 fu2 fu2 http://flybase.net/reports/FBgn0029173.html FBgn0032044 protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" 0005634=nucleus "FU12, CG9233" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG9233 16-Dec-15 2015_12 "decreased cell death,recessive,somatic clone,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024233 aos::spi argos::spi http://flybase.net/reports/FBgn0024233.html engineered_fusion_gene "argos::spi, gil::spi" 16-Dec-15 2015_12 visible "eye,cone cell,pigment cell,wing vein" FBgn0036668 CG9715 http://flybase.net/reports/FBgn0036668.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "IPR001878=Zinc finger, CCHC-type" CG9715 16-Dec-15 2015_12 "viable,visible,body color defective" mesothoracic tergum DRSC11099 E 0.349579035 0.994289176 3.475520397 -0.502611674 -0.179284216 0.402684993 FBgn0265701 CR44508 http://flybase.net/reports/FBgn0265701.html non_protein_coding_gene lincRNA.966 CR44508 16-Dec-15 2015_12 FBgn0051100 CG31100 http://flybase.net/reports/FBgn0051100.html "FBgn0037649, FBgn0037651" protein_coding_gene 0015145=monosaccharide transmembrane transporter activity "0055085=transmembrane transport, 0015749=monosaccharide transport" 0016021=integral component of membrane "CG11978, CG11976" "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like" CG31100 16-Dec-15 2015_12 "viable,fertile" FBgn0265591 CR44418 http://flybase.net/reports/FBgn0265591.html non_protein_coding_gene CR44418 16-Dec-15 2015_12 FBgn0035343 CG16762 http://flybase.net/reports/FBgn0035343.html protein_coding_gene IPR007931=Protein of unknown function DUF725 CG16762 16-Dec-15 2015_12 "viable,fertile" FBgn0005401 l(1)10Aj lethal (1) 10Aj http://flybase.net/reports/FBgn0005401.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0014062 Su(tor)3-1 Su(tor)3-1 http://flybase.net/reports/FBgn0014062.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0267155 CR45595 http://flybase.net/reports/FBgn0267155.html non_protein_coding_gene CR45595 16-Dec-15 2015_12 FBgn0032783 CG10237 http://flybase.net/reports/FBgn0032783.html protein_coding_gene "0005215=transporter activity, 0008431=vitamin E binding, 0016918=retinal binding" 0006810=transport 0005622=intracellular "IPR011074=CRAL/TRIO, N-terminal domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251=CRAL-TRIO lipid binding domain" CG10237 16-Dec-15 2015_12 ENSDARG00000070644(ttpal) ENSXETG00000001776(TGas020k08.1) ENSMUSG00000017679(Ttpal) ENSG00000124120(TTPAL) FBgn0000319 Chc Clathrin heavy chain http://flybase.net/reports/FBgn0000319.html "FBgn0014972, FBgn0028268" protein_coding_gene "0005198=structural molecule activity, 0005515=protein binding, 0032051=clathrin light chain binding" "0006886=intracellular protein transport, 0035159=regulation of tube length, open tracheal system, 0006897=endocytosis, 0030198=extracellular matrix organization, 0040008=regulation of growth, 0007268=synaptic transmission, 0045451=pole plasm oskar mRNA localization, 0033227=dsRNA transport, 0045807=positive regulation of endocytosis, 0016183=synaptic vesicle coating, 0007594=puparial adhesion, 0007291=sperm individualization, 0035002=liquid clearance, open tracheal system, 0045747=positive regulation of Notch signaling pathway, 0033363=secretory granule organization, 0046667=compound eye retinal cell programmed cell death, 0016079=synaptic vesicle exocytosis, 0048749=compound eye development, 0007269=neurotransmitter secretion, 0008103=oocyte microtubule cytoskeleton polarization" "0030130=clathrin coat of trans-Golgi network vesicle, 0030141=secretory granule, 0031410=cytoplasmic vesicle, 0030135=coated vesicle, 0005811=lipid particle, 0030125=clathrin vesicle coat, 0030132=clathrin coat of coated pit, 0048471=perinuclear region of cytoplasm, 0071439=clathrin complex, 0005905=coated pit, 0008021=synaptic vesicle, 0030136=clathrin-coated vesicle, 0005802=trans-Golgi network, 0005886=plasma membrane, 0005938=cell cortex, 0030129=clathrin coat of synaptic vesicle" "D-Chc, Clathrin hc, l(1)G0438, chc1, Cla, CG9012, clathrin, Clh, l(1)VI, Clathrin, CLH, chc, clathrin heavy-chain, clathrin heavy chain, l(1)13Fb, CHC, dCHC" "IPR016025=Clathrin, heavy chain, linker/propeller domain, IPR011990=Tetratricopeptide-like helical domain, IPR000547=Clathrin, heavy chain/VPS, 7-fold repeat, IPR022365=Clathrin, heavy chain, propeller repeat, IPR015348=Clathrin, heavy chain, linker, core motif, IPR001473=Clathrin, heavy chain, propeller, N-terminal, IPR016024=Armadillo-type fold, IPR016341=Clathrin, heavy chain" CG9012 16-Dec-15 2015_12 "ENSDARG00000056251,ENSDARG00000043493(cltca)" YGL206C(CHC1) WBGene00011867(chc-1) ENSXETG00000010738(cltc) ENSMUSG00000047126(Cltc) "ENSG00000141367(CLTC),ENSG00000070371(CLTCL1)" adult stage "viable,neurophysiology defective,chemical conditional,lethal,recessive,increased cell death,wild-type,cell lethal,cell autonomous,germline clone,neoplasia,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during larval stage,lethal - all die before end of pupal stage,polyphasic,partially lethal - majority die,male sterile,female semi-sterile,partially,heat sensitive,neuroanatomy defective" "eye disc,secondary pigment cell,tertiary pigment cell,egg chamber,germline clone,presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,spermatozoon,primary spermatocyte cyst,major mitochondrial derivative,minor mitochondrial derivative,spermatid & nucleus,microtubule,oocyte,interommatidial bristle,embryonic/larval garland cell,synaptic vesicleAppl.G1a,synapseAppl.G1a,bouton,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,eye" DRSC20229 E 0.704200604 0.604525578 6.130681265 1.709516752 0.442769017 -0.050066709 FBgn0036181 Muc68Ca Mucin 68Ca http://flybase.net/reports/FBgn0036181.html protein_coding_gene 0005201=extracellular matrix structural constituent 0031012=extracellular matrix "Muc68Ca, cg18331, CG18331" CG18331 16-Dec-15 2015_12 viable FBgn0263217 CR43387 http://flybase.net/reports/FBgn0263217.html non_protein_coding_gene CR43387 16-Dec-15 2015_12 FBgn0266396 CR45036 http://flybase.net/reports/FBgn0266396.html non_protein_coding_gene CR45036 16-Dec-15 2015_12 FBgn0266279 CR44964 http://flybase.net/reports/FBgn0266279.html non_protein_coding_gene CR44964 16-Dec-15 2015_12 FBgn0083908 DJ817 DJ817 http://flybase.net/reports/FBgn0083908.html gene 16-Dec-15 2015_12 long lived FBgn0038299 Spn88Eb Serpin 88Eb http://flybase.net/reports/FBgn0038299.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis, 0022416=chaeta development, 0009620=response to fungus, 0010951=negative regulation of endopeptidase activity" 0005615=extracellular space "Dm-serpin-88Eb, CG6687" "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG6687 16-Dec-15 2015_12 "viable,body color defective,fertile" mesothoracic tergum FBgn0261675 Npc1b Niemann-Pick type C-1b http://flybase.net/reports/FBgn0261675.html "FBgn0031140, FBgn0001560, FBgn0013506, FBgn0031136" protein_coding_gene 0008158=hedgehog receptor activity "0007417=central nervous system development, 0007422=peripheral nervous system development, 0007391=dorsal closure, 0030299=intestinal cholesterol absorption" "0005886=plasma membrane, 0016021=integral component of membrane" "lN5, npc1b, Niemann-Pick, l(1)2-3, R9-28, section 7, lt2-14a, Q256, l152, AF2/19, unnamed, CG12092, lethal (1) 19Ec, l151, dncp1b, 151, l(1)19Ec, l(1)R-9-28, 7, NPC1b, section 4, R-9-28, 4" "IPR000731=Sterol-sensing domain, IPR003392=Patched" CG12092 16-Dec-15 2015_12 YPL006W(NCR1) WBGene00003561(ncr-1) FBgn0002197 l(3)67Aa lethal (3) 67Aa http://flybase.net/reports/FBgn0002197.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033395 Cyp4p2 Cyp4p2 http://flybase.net/reports/FBgn0033395.html protein_coding_gene "0020037=heme binding, 0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG1944, cytochrome P450, 4p2, CYP4P2" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG1944 16-Dec-15 2015_12 YDR402C(DIT2) viable FBgn0034166 CG6472 http://flybase.net/reports/FBgn0034166.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "IPR000734=Triacylglycerol lipase family, IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold" CG6472 16-Dec-15 2015_12 viable FBgn0003718 tlc tender little chaetae http://flybase.net/reports/FBgn0003718.html gene "l(1)comega247, l(1)2Bi" 16-Dec-15 2015_12 "viable,lethal" FBgn0005294 mei-2439 meiotic 2439 http://flybase.net/reports/FBgn0005294.html gene 2439 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0060371 l(3)S137304c lethal (3) S137304c http://flybase.net/reports/FBgn0060371.html gene 1373/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0262061 EG162 http://flybase.net/reports/FBgn0262061.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030759 CG13014 http://flybase.net/reports/FBgn0030759.html protein_coding_gene CG13014 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0001452 l(1)7Df lethal (1) 7Df http://flybase.net/reports/FBgn0001452.html gene 16-Dec-15 2015_12 "lethal,maternal effect,cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "egg chamber,germline clone,maternal effect" FBgn0051861 CG31861 http://flybase.net/reports/FBgn0051861.html FBgn0032418 protein_coding_gene CG17215 CG31861 16-Dec-15 2015_12 DRSC21665 K -0.356481981 -0.6689832 -0.435951315 -0.232123151 1.844786975 -0.541635829 FBgn0000350 corr corrugated wing http://flybase.net/reports/FBgn0000350.html gene 16-Dec-15 2015_12 "visible,cold sensitive" "wing,cold sensitive" FBgn0028872 CG18095 http://flybase.net/reports/FBgn0028872.html FBgn0032543 protein_coding_gene "gp150-like, DS05899.7, BG:DS05899.7" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG18095 16-Dec-15 2015_12 ENSMUSG00000046070(Igfals) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0065231 l(2)SH2172 lethal (2) SH2172 http://flybase.net/reports/FBgn0065231.html gene l(2)SH2 2172 16-Dec-15 2015_12 "lethal,recessive" FBgn0083279 E(smoDN)2364 Enhancer of smoDN 2364 http://flybase.net/reports/FBgn0083279.html gene 16-Dec-15 2015_12 FBgn0024657 l(2)k07813 lethal (2) k07813 http://flybase.net/reports/FBgn0024657.html gene 78/13 16-Dec-15 2015_12 "lethal,recessive,visible" "imaginal disc,wing" FBgn0022107 l(2)k07015 lethal (2) k07015 http://flybase.net/reports/FBgn0022107.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023499 HmpII HmpII http://flybase.net/reports/FBgn0023499.html gene 16-Dec-15 2015_12 FBgn0053739 snmRNA:430:CR33739 snmRNA:430:CR33739 http://flybase.net/reports/FBgn0053739.html non_protein_coding_gene CR33739 CR33739 16-Dec-15 2015_12 FBgn0014226 l(2)31Ee lethal (2) 31Ee http://flybase.net/reports/FBgn0014226.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085651 CG41490 http://flybase.net/reports/FBgn0085651.html FBan0041490 protein_coding_gene 16-Dec-15 2015_12 FBgn0037009 CG5104 http://flybase.net/reports/FBgn0037009.html FBgn0062951 protein_coding_gene 0016192=vesicle-mediated transport 0016021=integral component of membrane BcDNA:RH26504 "IPR007305=Vesicle transport protein, Got1/SFT2-like, IPR011691=Vesicle transport protein, SFT2-like" CG5104 16-Dec-15 2015_12 "ENSDARG00000007362(sft2d1),ENSDARG00000071159(zgc:112392),ENSDARG00000071157,ENSDARG00000071145,ENSDARG00000071153" WBGene00009191(F27D4.7) ENSXETG00000025905(TEgg079d07.1) "ENSMUSG00000069899(Gm12166),ENSMUSG00000073468(Sft2d1),ENSMUSG00000040848(Sft2d2)" "ENSG00000213064(SFT2D2),ENSG00000198818(SFT2D1)" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0021983 l(2)k09854 lethal (2) k09854 http://flybase.net/reports/FBgn0021983.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034286 dpr13 defective proboscis extension response 13 http://flybase.net/reports/FBgn0034286.html "FBgn0034287, FBgn0053996, FBtr0086815, FBpp0085994, FBtr0086816, FBpp0085995" protein_coding_gene 0007606=sensory perception of chemical stimulus "Dm_2R:58906, CT34204, Dpr-13, Dpr13, CG14493, CG12557, CG33996, dpr13" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain" CG33996 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) viable DRSC06464 E 1.212411109 -0.030263679 0.382473779 1.543605966 -0.001506058 0.593449396 FBgn0259649 B1365 http://flybase.net/reports/FBgn0259649.html gene 16-Dec-15 2015_12 visible "chaeta,ectopic,wing,distal" FBgn0062535 anon-6972 anon-6972 http://flybase.net/reports/FBgn0062535.html gene 6972 16-Dec-15 2015_12 FBgn0034296 CG10912 http://flybase.net/reports/FBgn0034296.html protein_coding_gene 0009631=cold acclimation IPR007931=Protein of unknown function DUF725 CG10912 16-Dec-15 2015_12 viable FBgn0017360 l(3)C18 lethal (3) C18 http://flybase.net/reports/FBgn0017360.html gene C18 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0065425 l(2)SH1515 lethal (2) SH1515 http://flybase.net/reports/FBgn0065425.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000932 fs(2)A2 female sterile (2) A2 http://flybase.net/reports/FBgn0000932.html gene 16-Dec-15 2015_12 "female sterile,recessive,mitotic cell cycle defective,lethal,maternal effect" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0030610 CG9065 http://flybase.net/reports/FBgn0030610.html protein_coding_gene 0016531=copper chaperone activity "0008535=respiratory chain complex IV assembly, 0006825=copper ion transport" 0005758=mitochondrial intermembrane space "COXS, Complex IV copper chaperone, Cytochrome c oxidase copper chaperone" "IPR007745=Cytochrome c oxidase copper chaperone, IPR009069=Cysteine alpha-hairpin motif superfamily" CG9065 16-Dec-15 2015_12 "ENSDARG00000067747,ENSDARG00000069920(cox17)" YLL009C(COX17) WBGene00018240(F40G9.2) ENSXETG00000027716(COX17) ENSMUSG00000046516(Cox17) "ENSG00000138495(COX17),ENSG00000205105" "viable,visible" trichogen cell DRSC20145 K -0.271205829 1.353639737 0.149653573 0.037868839 1.868271847 0.631868907 FBgn0038400 CG5903 http://flybase.net/reports/FBgn0038400.html "FBgn0027665, FBgn0061520" protein_coding_gene "anon-WO0118547.99, anon-EST:Posey87, bs05g07.y1" IPR019166=Apolipoprotein O//MICOS complex subunit Mic27 CG5903 16-Dec-15 2015_12 "ENSDARG00000026444(apoob),ENSDARG00000046154" WBGene00019333(K02F3.10) "ENSMUSG00000025525(Apool),ENSMUSG00000079508(Apoo)" "ENSG00000155008(APOOL),ENSG00000184831(APOO)" "viable,fertile" FBgn0032980 CG16948 http://flybase.net/reports/FBgn0032980.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039187 CG6454 http://flybase.net/reports/FBgn0039187.html protein_coding_gene IPR000008=C2 domain CG6454 16-Dec-15 2015_12 WBGene00018719(F52H2.7) ENSMUSG00000030279(5730419I09Rik) ENSG00000111731(KIAA0528) viable FBgn0264330 CG43789 http://flybase.net/reports/FBgn0264330.html protein_coding_gene CG43789 16-Dec-15 2015_12 FBgn0064211 UY126 UY126 http://flybase.net/reports/FBgn0064211.html gene 16-Dec-15 2015_12 chemical resistant FBgn0262377 mir-2a-1 mir-2a-1 stem loop http://flybase.net/reports/FBgn0262377.html "FBgn0046826, FBgn0262192" miRNA_gene "0060548=negative regulation of cell death, 0007476=imaginal disc-derived wing morphogenesis, 0045947=negative regulation of translational initiation" "miR-2a-1, CR42899, miR-2a, dme-miR-2a, miR-2, mir-2a-1, miR2a, CR32965, 2a-1, dme-mir-2a-1, mir-2, miR2, dme-miR-2a-3p, mir-2a" CR42899 16-Dec-15 2015_12 embryonic stage -- adult stage viable FBgn0267350 PI4KIIIë± Phosphatidylinositol 4-kinase III ë± http://flybase.net/reports/FBgn0267350.html "FBgn0261922, FBgn0040335, FBgn0029633, FBgn0259120, FBgn0001406" protein_coding_gene 0004430=1-phosphatidylinositol 4-kinase activity "0007293=germarium-derived egg chamber formation, 0030010=establishment of cell polarity, 0071711=basement membrane organization, 0048477=oogenesis, 0008582=regulation of synaptic growth at neuromuscular junction, 0007015=actin filament organization, 0007009=plasma membrane organization, 0048599=oocyte development, 0048015=phosphatidylinositol-mediated signaling, 0016310=phosphorylation, 0046854=phosphatidylinositol phosphorylation, 0035329=hippo signaling" "zw-2, zw2, l(1)3Ah, Pi4KIIIalpha, stt4, EG:BACR7C10.2, PI4KIIIalpha, phosphatidylinositol 4-kinase IIIalpha, CG10260, PI4K, l(1)zw2, l(1)17-59, ZW-2, zeste-white 2, PI4KinaseIIIalpha, PI4KIII[[alpha]], l(1)VA722, lethal (1) 3Ah, Phosphatidylinositol 4-kinase III alpha" "IPR015433=Phosphatidylinositol Kinase, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR001263=Phosphoinositide 3-kinase, accessory (PIK) domain, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR016024=Armadillo-type fold, IPR011009=Protein kinase-like domain" CG10260 16-Dec-15 2015_12 "ENSDARG00000009527,ENSDARG00000062823(zgc:172062)" YLR305C(STT4) WBGene00013557(Y75B8A.24) ENSXETG00000022408() ENSMUSG00000041720(Pi4ka) ENSG00000133511 FBgn0003210 rb ruby http://flybase.net/reports/FBgn0003210.html FBgn0025523 protein_coding_gene 0008565=protein transporter activity "0006727=ommochrome biosynthetic process, 0046907=intracellular transport, 0060967=negative regulation of gene silencing by RNA, 0008057=eye pigment granule organization, 0031396=regulation of protein ubiquitination, 0010883=regulation of lipid storage, 0008340=determination of adult lifespan, 0006887=exocytosis, 0006726=eye pigment biosynthetic process, 0007040=lysosome organization, 0016183=synaptic vesicle coating, 0006901=vesicle coating, 0007220=Notch receptor processing, 0006897=endocytosis, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport" "0030135=coated vesicle, 0008021=synaptic vesicle, 0030123=AP-3 adaptor complex" "beta3, apl6, cg11427, CG11427, Rb, Ruby, AP-3beta, Adaptor Protein complex 3, beta subunit" "IPR026740=AP-3 complex subunit beta, IPR026739=AP complex subunit beta, IPR011989=Armadillo-like helical, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR029390=AP-3 complex subunit beta, C-terminal domain, IPR016024=Armadillo-type fold" CG11427 16-Dec-15 2015_12 ENSDARG00000063432 YGR261C(APL6) WBGene00000163(apb-3) "ENSMUSG00000062444(Ap3b2),ENSMUSG00000021686(Ap3b1)" "ENSG00000132842(AP3B1),ENSG00000103723(AP3B2)" " adult stage | female , adult stage , pharate adult stage | stage P13 , pupal stage , larval stage | third instar , embryonic stage " " subretinal glial cell

, pigment cell

, photoreceptor cell

, retina | restricted

, adult brain cortex | restricted

" "visual behavior defective,fertile,viable,eye color defective,recessive,visible,short lived,male" "secondary pigment cell pigment granule,tertiary pigment cell pigment granule,subretinal glial cell & pigment granule,pigment cell,ocellus pigment granule,testis pigment cell,Malpighian tubule,photoreceptor cell pigment granule" DRSC27940 K 0.716520771 -0.110183952 -0.015285235 0.11984677 2.044949488 0.328472739 FBgn0001640 l(1)dn20 lethal (1) discs normal 20 http://flybase.net/reports/FBgn0001640.html gene l(1)d.norm.-20 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0013318 Pcp21 Pupal-cuticle-protein-21kD http://flybase.net/reports/FBgn0013318.html gene 16-Dec-15 2015_12 FBgn0262074 JC12 http://flybase.net/reports/FBgn0262074.html gene 0072347=response to anesthetic 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0028357 l(1)G0152 lethal (1) G0152 http://flybase.net/reports/FBgn0028357.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044405 Scim22 Sensitized chromosome inheritance modifier 22 http://flybase.net/reports/FBgn0044405.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0016888 l(2)39DEm lethal (2) 39DEm http://flybase.net/reports/FBgn0016888.html gene K236 16-Dec-15 2015_12 lethal FBgn0000571 extra-lamina-fiber extra lamina fiber http://flybase.net/reports/FBgn0000571.html gene "elf, opm37, H37" 16-Dec-15 2015_12 lamina FBgn0040786 CG14104 http://flybase.net/reports/FBgn0040786.html protein_coding_gene "IPR010760=DNA repair protein, Swi5" CG14104 16-Dec-15 2015_12 "viable,fertile" DRSC10106 K 0.242932208 0.158863646 0.050333917 0.211046516 -0.052877052 1.504246204 FBgn0013686 mt:lrRNA mitochondrial large ribosomal RNA http://flybase.net/reports/FBgn0013686.html "FBgn0002867, FBgn0025213, FBgn0025251, FBgn0025280" rRNA_gene 0003735=structural constituent of ribosome 0007279=pole cell formation "0005762=mitochondrial large ribosomal subunit, 0005739=mitochondrion, 0043186=P granule" "mtlRNA, 16SrRNA, mtrRNA, mlrRNA, lrRNA, anon-fast-evolving-2F10, anon-EST:fe1F3, anon-fast-evolving-1F3, 16S RNA, mt large rRNA, mitochondrial large rRNA, anon-EST:fe2F10, mt 16S rDNA, Lr mtDNA, rrnL, mt 16S rRNA, anon-fast-evolving-1A1, 16S mtRNA, 16S mitochondrial rDNA, 16S rRNA, CR34094, rRNA-16s, Large Subunit rRNA, mtlrRNA, unnamed, B4, anon-EST:fe1A1, 16S, 16S ribosomal DNA, mtlr RNA" CR34094 16-Dec-15 2015_12 FBgn0015803 RtGEF Rho-type guanine nucleotide exchange factor http://flybase.net/reports/FBgn0015803.html protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0032947=protein complex scaffold, 0005089=Rho guanyl-nucleotide exchange factor activity" "0050807=regulation of synapse organization, 0043547=positive regulation of GTPase activity, 0046620=regulation of organ growth, 0035332=positive regulation of hippo signaling" 0097482=muscle cell postsynaptic density "Rho/RacGEF, dPix, RhoGEF, PAK-interacting exchange factor, Pix, rtGEF, pix, CG10043, rhoGEF, rho-type guanine exchange factor, betaPIX, Drosophila rho-type guanine exchange factor, 38C.40, ARHGEF7, DrhoGEF, dpix, beta-PIX, DrtGEF" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001452=SH3 domain, IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain" CG10043 16-Dec-15 2015_12 "ENSDARG00000006299(arhgef7a),ENSDARG00000006683(LOC558288)" "ENSXETG00000017497(ARHGEF6),ENSXETG00000008213(ARHGEF7)" "ENSMUSG00000031511(Arhgef7),ENSMUSG00000031133(Arhgef6)" "ENSG00000102606(ARHGEF7),ENSG00000129675(ARHGEF6)" " embryonic stage | stage 12-15 , adult stage && oogenesis stage , embryonic stage | stage 6-9 , adult stage && oogenesis stage | stage , follicle cell

, embryonic/larval digestive system

, ventral furrow

, oocyte

, nurse cell

, neuroblast | ventral

, stomodeal invagination

, posterior plate of cibarium

, amnioproctodeal invagination

, anterior midgut proper primordium

, cephalic furrow

,

ubiquitous , inclusive hindgut primordium

, mesoderm

, posterior midgut proper primordium

" "neuroanatomy defective,neurophysiology defective,viable,partially lethal - majority die" "postsynaptic membrane,synaptic vesiclePJ19),NMJ bouton,postsynaptic membranePJ19),t-bar" FBgn0044397 Scim30 Sensitized chromosome inheritance modifier 30 http://flybase.net/reports/FBgn0044397.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0013573 l(3)82Fa lethal (3) 82Fa http://flybase.net/reports/FBgn0013573.html gene 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal,recessive" mitotic cell cycle FBgn0262029 d dachs http://flybase.net/reports/FBgn0262029.html "FBgn0032045, FBgn0086896, FBgn0000410, FBgn0025975, FBgn0032046, FBgn0051610, FBgn0069196" protein_coding_gene "0032947=protein complex scaffold, 0000146=microfilament motor activity, 0005524=ATP binding, 0051015=actin filament binding, 0005515=protein binding, 0016887=ATPase activity, 0042623=ATPase activity, coupled, 0003774=motor activity" "0035218=leg disc development, 0035220=wing disc development, 0045927=positive regulation of growth, 0008586=imaginal disc-derived wing vein morphogenesis, 0042067=establishment of ommatidial planar polarity, 0045572=positive regulation of imaginal disc growth, 0001736=establishment of planar polarity" "0016459=myosin complex, 0005737=cytoplasm" "anon-EST:Liang-1.78, Ds, clone 1.78, myosin 29D, l(2)c00146, Dachs, AAF52683, DmMyo20, dachs, 29C3-D1, 29CD, lethal (2) c00146, CG10595, CG31610, Myo29D, unconventional myosin 29D, D, unnamed, CG13087, CG42840" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000048=IQ motif, EF-hand binding site, IPR001609=Myosin head, motor domain" CG42840 16-Dec-15 2015_12 DRSC02191 I 2.369040264 0.353579274 0.276700613 0.277530314 -0.400055973 -0.710342409 FBgn0086671 snoRNA:ë¬28S-2876 snoRNA:ë¬28S-2876 http://flybase.net/reports/FBgn0086671.html "FBgn0082982, FBgn0065049, FBgn0053646" snoRNA_gene 0005730=nucleolus "Dm-825, snoR825, snoRNA:825, Psi28S-2876, CR33646, psi28S-2876, Psi28S-2876(SnoR825)" CR33646 16-Dec-15 2015_12 FBgn0262003 CG42821 http://flybase.net/reports/FBgn0262003.html "FBgn0054035, FBgn0082895" protein_coding_gene "BP1011, CG34035" CG42821 16-Dec-15 2015_12 FBgn0052409 CG32409 http://flybase.net/reports/FBgn0052409.html FBgn0063150 protein_coding_gene 0042254=ribosome biogenesis 0005634=nucleus BcDNA:LD24586 IPR007023=Ribosomal biogenesis regulatory protein CG32409 16-Dec-15 2015_12 ENSDARG00000003941(rrs1) YOR294W(RRS1) WBGene00007617(rrbs-1) ENSXETG00000023249(RRS1) ENSMUSG00000061024(Rrs1) ENSG00000179041(RRS1) "viable,visible" trichogen cell FBgn0033184 CG12736 http://flybase.net/reports/FBgn0033184.html protein_coding_gene "0003924=GTPase activity, 0003746=translation elongation factor activity, 0005525=GTP binding" "0006412=translation, 0006414=translational elongation" 0005739=mitochondrion "IPR004160=Translation elongation factor EFTu/EF1A, C-terminal, IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR031157=Tr-type G domain, conserved site, IPR005225=Small GTP-binding protein domain, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal" CG12736 16-Dec-15 2015_12 WBGene00007001(tufm-2) ENSXETG00000028019() "viable,fertile" FBgn0051806 CG31806 http://flybase.net/reports/FBgn0051806.html "FBgn0032623, FBgn0063618" protein_coding_gene CG4855 CG31806 16-Dec-15 2015_12 viable DRSC02787 IE 1.407661376 1.560435832 1.632418081 0.160877544 0.041521532 0.882709155 FBgn0004480 l(1)air5 lethal aberrant immune response 5 http://flybase.net/reports/FBgn0004480.html gene 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype,polyphasic" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0036369 CG10089 http://flybase.net/reports/FBgn0036369.html protein_coding_gene 0008138=protein tyrosine/serine/threonine phosphatase activity 0006470=protein dephosphorylation MKP-like "IPR000340=Dual specificity phosphatase, catalytic domain, IPR024950=Dual specificity phosphatase, IPR020422=Dual specificity protein phosphatase domain, IPR020417=Atypical dual specificity phosphatase, IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain" CG10089 16-Dec-15 2015_12 viable FBgn0035882 CG13666 http://flybase.net/reports/FBgn0035882.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036922 CG14182 http://flybase.net/reports/FBgn0036922.html protein_coding_gene CG14182 16-Dec-15 2015_12 "ENSDARG00000035837(zgc:153595),ENSDARG00000069872" ENSXETG00000016695() ENSMUSG00000046096(BC030336) "viable,body color defective" mesothoracic tergum FBgn0022731 l(2)GPMG-6 lethal (2) GPMG-6 http://flybase.net/reports/FBgn0022731.html gene GPMG-6 16-Dec-15 2015_12 "lethal,recessive" FBgn0045470 Gr93b Gustatory receptor 93b http://flybase.net/reports/FBgn0045470.html "FBgn0038907, FBgn0041228, FBgn0051336" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "93F.2, Gr93F2, Gustatory receptor 93F.2, gustatory receptor 93b, CG31336, CG13411, GR93b, GR93F.2" IPR013604=7TM chemoreceptor CG31336 16-Dec-15 2015_12 viable FBgn0025577 M(3)40l30 M(3)40l30 http://flybase.net/reports/FBgn0025577.html gene 16-Dec-15 2015_12 Minute FBgn0003571 Su(Pc)37D Suppressor of Polycomb at 37D http://flybase.net/reports/FBgn0003571.html gene "Suppressor-of-Polycomb-37D, Su(Pc)" 16-Dec-15 2015_12 "lethal,recessive" FBgn0030512 CG9940 http://flybase.net/reports/FBgn0030512.html protein_coding_gene "0005524=ATP binding, 0016810=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, 0003952=NAD+ synthase (glutamine-hydrolyzing) activity" 0009435=NAD biosynthetic process "Q9VYA0, 145027_at, NADS" "IPR014445=Glutamine-dependent NAD(+) synthetase, IPR003010=Carbon-nitrogen hydrolase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR003694=NAD(+) synthetase, IPR022310=NAD/GMP synthase" CG9940 16-Dec-15 2015_12 ENSDARG00000009903(nadsyn1) YHR074W(QNS1) WBGene00007698(C24F3.4) ENSMUSG00000031090(Nadsyn1) ENSG00000172890(NADSYN1) viable FBgn0053542 upd3 unpaired 3 http://flybase.net/reports/FBgn0053542.html "FBgn0030909, FBgn0030910, FBgn0069074" protein_coding_gene "0005102=receptor binding, 0005125=cytokine activity" "0046425=regulation of JAK-STAT cascade, 0007259=JAK-STAT cascade, 0046427=positive regulation of JAK-STAT cascade, 0060729=intestinal epithelial structure maintenance, 0019730=antimicrobial humoral response, 0008284=positive regulation of cell proliferation, 0006955=immune response, 0044719=regulation of imaginal disc-derived wing size, 0038001=paracrine signaling, 0048477=oogenesis" 0005576=extracellular region "CG15062, outstretched, upd-3, odsy, CG15062/CG5963, cg15062, Unpaired3, unpaired3, os, upd homolog, CG33542, sy, Upd-3, UPD3, unpaired-like protein 3, small-eye, unpaired-3, outstretched-smalleye, cg5963, Upd-like, Unpaired 3beta, CG5963, od, unpaired, Unpaired 3, Upd3" CG33542 16-Dec-15 2015_12 "viable,fertile,immune response defective,size defective,visible" "eye,border follicle cell,midgut,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 2,embryonic abdominal segment 1,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic head segment,posterior spiracle primordium,wing,posterior" FBgn0001861 l(1)10Ci lethal (1) 10Ci http://flybase.net/reports/FBgn0001861.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0052304 obst-I obstructor-I http://flybase.net/reports/FBgn0052304.html FBgn0035326 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "CG32304, CG13805" IPR002557=Chitin binding domain CG32304 16-Dec-15 2015_12 viable FBgn0003437 slim-bristle slim bristle http://flybase.net/reports/FBgn0003437.html gene smb 16-Dec-15 2015_12 "female sterile,viable,male fertile,visible" macrochaeta FBgn0082966 snoRNA:ë¬28S-3327b snoRNA:ë¬28S-3327b http://flybase.net/reports/FBgn0082966.html snoRNA_gene "CR34643, chr3L:13016868..13016958, pug28S-3327, Psi28S-3327b, psi28S-3327b" CR34643 16-Dec-15 2015_12 FBgn0020853 fs(3)A107 fs(3)A107 http://flybase.net/reports/FBgn0020853.html gene 3-A107 16-Dec-15 2015_12 "chemical sensitive,recessive,female sterile" FBgn0026205 mie michelangelo http://flybase.net/reports/FBgn0026205.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 FBgn0030940 CG15040 http://flybase.net/reports/FBgn0030940.html protein_coding_gene CG15040 16-Dec-15 2015_12 viable DRSC21482 IE 4.261909127 2.216553446 7.089192586 3.585175828 0.215368303 -0.05010909 FBgn0062677 EP2416 EP2416 http://flybase.net/reports/FBgn0062677.html gene 16-Dec-15 2015_12 FBgn0014249 l(2)60Ab lethal (2) 60Ab http://flybase.net/reports/FBgn0014249.html gene 16-Dec-15 2015_12 lethal FBgn0039580 Gfat2 Glutamine:fructose-6-phosphate aminotransferase 2 http://flybase.net/reports/FBgn0039580.html protein_coding_gene "0004360=glutamine-fructose-6-phosphate transaminase (isomerizing) activity, 0030246=carbohydrate binding" "0005975=carbohydrate metabolic process, 1901137=carbohydrate derivative biosynthetic process" "Dmel/GFAT2, CG1345" "IPR001347=Sugar isomerase (SIS), IPR017932=Glutamine amidotransferase type 2 domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR005855=Glucosamine-fructose-6-phosphate aminotransferase, isomerising" CG1345 16-Dec-15 2015_12 ENSDARG00000044094(gfpt2) YKL104C(GFA1) "WBGene00008546(F07A11.2),WBGene00009035(F22B3.4)" ENSXETG00000008199(GFPT1) "ENSMUSG00000020363(Gfpt2),ENSMUSG00000029992(Gfpt1)" "ENSG00000131459(GFPT2),ENSG00000198380(GFPT1)" "lethal,viable" embryonic/larval brain FBgn0052129 tRNA:CR32129 transfer RNA:CR32129 http://flybase.net/reports/FBgn0052129.html FBgn0060126 tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:P:AGG:AE002602-a, chr3L.trna22-ProAGG, CR32129, AE002602.trna16-ProAGG" CR32129 16-Dec-15 2015_12 FBgn0266672 Sec8 Sec8 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266672.html "FBgn0266612, FBgn0262603, FBgn0086685, FBgn0037373, FBgn0042631, FBgn0025934" protein_coding_gene "0007286=spermatid development, 0016192=vesicle-mediated transport, 0007110=meiosis I cytokinesis, 0015031=protein transport, 0016081=synaptic vesicle docking, 0007111=meiosis II cytokinesis, 0007298=border follicle cell migration, 0016080=synaptic vesicle targeting, 0000916=actomyosin contractile ring contraction, 0007009=plasma membrane organization, 0007269=neurotransmitter secretion, 0090522=vesicle tethering involved in exocytosis, 0006904=vesicle docking involved in exocytosis, 0050803=regulation of synapse structure or activity, 0043147=meiotic spindle stabilization" "0016028=rhabdomere, 0000145=exocyst, 0005737=cytoplasm, 0016324=apical plasma membrane, 0016020=membrane, 0005886=plasma membrane, 0009925=basal plasma membrane" "sec8, dsec8, funnel cakes, fun, Sec8p, CG2095" IPR007191=Sec8 exocyst complex component specific domain CG2095 16-Dec-15 2015_12 ENSDARG00000004336(exoc4) YPR055W(SEC8) WBGene00004753(sec-8) ENSMUSG00000029763(Exoc4) ENSG00000131558(EXOC4) FBgn0003403 shy shy http://flybase.net/reports/FBgn0003403.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0261872 scaf6 http://flybase.net/reports/FBgn0261872.html "FBgn0053522, FBgn0036692, FBgn0036693, FBgn0036694, FBgn0052168, FBgn0082866, FBgn0082859" protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome" 0005681=spliceosomal complex "CG6626, CG32168, CG6615, CG33522, CG14058, unnamed, BP1040, scaf6, BP1047" "IPR006569=CID domain, IPR008942=ENTH/VHS, IPR000061=SWAP/Surp, IPR000467=G-patch domain, IPR006903=RNA polymerase II-binding domain" CG33522 16-Dec-15 2015_12 ENSDARG00000021812(cherp) WBGene00006442(tag-65) ENSXETG00000002072(cherp) ENSMUSG00000052488(Cherp) ENSG00000085872(CHERP) DRSC10676 I 2.047034402 0.476869647 -0.3036928 0.765182307 -0.266471715 0.059363214 FBgn0264869 CR44060 http://flybase.net/reports/FBgn0264869.html non_protein_coding_gene CR44060 16-Dec-15 2015_12 FBgn0067671 over-easy over easy http://flybase.net/reports/FBgn0067671.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0041119 l(2)cl-R11 lethal (2) cell lethal R11 http://flybase.net/reports/FBgn0041119.html gene "cl2R11, cl-R11" 16-Dec-15 2015_12 lethal FBgn0266537 CR45098 http://flybase.net/reports/FBgn0266537.html non_protein_coding_gene CR45098 16-Dec-15 2015_12 FBgn0033955 CG12866 http://flybase.net/reports/FBgn0033955.html protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG12866 16-Dec-15 2015_12 viable FBgn0002567 Rab32 Rab32 http://flybase.net/reports/FBgn0002567.html "FBgn0015788, FBgn0062240" protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding" "0007611=learning or memory, 0048072=compound eye pigmentation, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0008355=olfactory learning, 0032482=Rab protein signal transduction, 0006727=ommochrome biosynthetic process, 0006856=eye pigment precursor transport, 0010506=regulation of autophagy, 0010883=regulation of lipid storage, 0006913=nucleocytoplasmic transport, 0008057=eye pigment granule organization" "0055037=recycling endosome, 0016020=membrane, 0045202=synapse, 0031982=vesicle, 0005776=autophagic vacuole, 0005764=lysosome" "Rab32/RP1, Rab-RP1/CG8024, CG8024, rab32, Rab-related protein 1, 24652026, RAB-RP1, DRABR1, Lightoid, Rab7L1, Rab-RP1, DrabRP1, Rab32, anon-WO0118547.106, RabRP1, beck, DmRab32, ltd, A1Z7S1, Rab-r1, lightoid, 24652028" "IPR003579=Small GTPase superfamily, Rab type, IPR020849=Small GTPase superfamily, Ras type, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type, IPR002041=Ran GTPase" CG8024 16-Dec-15 2015_12 ENSMUSG00000043003(Rasef) "memory defective,viable,fertile,visible,recessive,neuroanatomy defective,eye color defective" "pigment cell,dopaminergic PPM1 neuron,dopaminergic PPL1 neuron,ocellus pigment granule,Malpighian tubule,primary pigment cell pigment granule,secondary pigment cell pigment granule,tertiary pigment cell pigment granule,eye photoreceptor cell & pigment granule" FBgn0014872 Pt13 Protein 13 http://flybase.net/reports/FBgn0014872.html gene 16-Dec-15 2015_12 FBgn0060873 l(3)S046020b lethal (3) S046020b http://flybase.net/reports/FBgn0060873.html gene 0460/20 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0052681 CG32681 http://flybase.net/reports/FBgn0052681.html protein_coding_gene CG32681 16-Dec-15 2015_12 DRSC17646 K -0.110735592 -0.010245136 -0.456635443 0.065189846 0.961738017 1.638462627 FBgn0052286 tRNA:CR32286 transfer RNA:CR32286 http://flybase.net/reports/FBgn0052286.html FBgn0060267 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna18-CysGCA, tRNA:C:GCA:AE002584-f, AE002584.trna18-CysGCA, CR32286" CR32286 16-Dec-15 2015_12 FBgn0025388 CG12179 http://flybase.net/reports/FBgn0025388.html protein_coding_gene EG:66A1.2 IPR029299=ALMS motif CG12179 16-Dec-15 2015_12 FBgn0013972 Gycë±99B Guanylyl cyclase ë±-subunit at 99B http://flybase.net/reports/FBgn0013972.html FBgn0010227 protein_coding_gene "0004383=guanylate cyclase activity, 0020037=heme binding" "0046956=positive phototaxis, 0006182=cGMP biosynthetic process, 0016056=rhodopsin mediated signaling pathway, 0035556=intracellular signal transduction" "0005737=cytoplasm, 0008074=guanylate cyclase complex, soluble" "CG1912, sGCalpha1, sGCalpha99B, guanylate cyclase 99B, Dgcalpha1, dgcalpha1, GCalpha1, Guanyl cyclase alpha-subunit at 63A, Gcalpha1, sGC, Dgc1, gycalpha, Gycalpha-99B, Gycalpha63A, dgc1, soluble guanylate cyclase, Soluble Guanylyl Cyclase alpha, unnamed, GYCa 99B, Gycalpha99B, SGCalpha, dgca1" "IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR011645=Haem NO binding associated, IPR011644=Heme-NO binding, IPR024096=NO signalling/Golgi transport ligand-binding domain" CG1912 16-Dec-15 2015_12 ENSDARG00000013787(gucy1a3) ENSXETG00000018493(GUCY1A2) "ENSMUSG00000041624(Gucy1a2),ENSMUSG00000033910(Gucy1a3)" "ENSG00000152402(GUCY1A2),ENSG00000164116(GUCY1A3)" " adult stage , embryonic stage&&pupal stage " " adult brain

, adult head

, optic lobe

, thoracico-abdominal ganglion

" adult stage " retina

, neuropil

, thoracico-abdominal ganglion

, medulla

, adult head

, optic lobe

, lamina

, lobula plate neuropil

, adult brain

" "visual behavior defective,recessive,phototaxis defective,wild-type,neuroanatomy defective,viable" "photoreceptor cell R7,photoreceptor cell R8" FBgn0069411 JJF174 JJF174 http://flybase.net/reports/FBgn0069411.html gene 16-Dec-15 2015_12 stress response defective FBgn0033367 PPO2 Prophenoloxidase 2 http://flybase.net/reports/FBgn0033367.html protein_coding_gene "0036264=dopamine monooxygenase activity, 0036263=L-DOPA monooxygenase activity" "0042417=dopamine metabolic process, 0050830=defense response to Gram-positive bacterium, 0035006=melanization defense response, 0050832=defense response to fungus, 0035011=melanotic encapsulation of foreign target" "0005576=extracellular region, 0005615=extracellular space" "DmePPO2, proPOA(3), proPO45, CG8193, phenoloxidase subunit A3, PO45, Phenoloxidase A3, prophenoloxidase 45, ProPO45, PPO2" "IPR000896=Hemocyanin/hexamerin middle domain, IPR014756=Immunoglobulin E-set, IPR008922=Uncharacterised domain, di-copper centre, IPR013788=Hemocyanin/hexamerin, IPR005204=Hemocyanin, N-terminal, IPR005203=Hemocyanin, C-terminal, IPR002227=Tyrosinase copper-binding domain" CG8193 16-Dec-15 2015_12 "viable,immune response defective" crystal cell FBgn0003348 sdp sandpaper http://flybase.net/reports/FBgn0003348.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001791 l(1)Mb16 lethal (1) Mb16 http://flybase.net/reports/FBgn0001791.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031886 Nuf2 Nuf2 http://flybase.net/reports/FBgn0031886.html FBgn0062167 protein_coding_gene "0022008=neurogenesis, 0007080=mitotic metaphase plate congression, 0007059=chromosome segregation, 0007052=mitotic spindle organization" "0000776=kinetochore, 0031262=Ndc80 complex" "dmNuf2, CG8902, anon-WO0118547.214, l(2)SH2 2276" IPR005549=Kinetochore protein Nuf2 CG8902 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,visible,partially lethal - majority die" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0086379 BG01918 http://flybase.net/reports/FBgn0086379.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective,long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0024660 l(2)k07160 lethal (2) k07160 http://flybase.net/reports/FBgn0024660.html gene 71/60 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0262416 mir-31a mir-31a stem loop http://flybase.net/reports/FBgn0262416.html "FBgn0067685, FBgn0262257" miRNA_gene "0046716=muscle cell cellular homeostasis, 0035282=segmentation" "CR33567, CR42964, dme-miR-31a-5p, mir-31a, dme-mir-31a, miR-31, miR-31a, dme-miR-31a, mir-31" CR42964 16-Dec-15 2015_12 viable FBgn0015341 anon-65Ea anon-65Ea http://flybase.net/reports/FBgn0015341.html gene gene 1 16-Dec-15 2015_12 FBgn0038318 CG6236 http://flybase.net/reports/FBgn0038318.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi7299997, gi23171351, gi21357449" "IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG6236 16-Dec-15 2015_12 WBGene00012762(Y41E3.1) FBgn0086200 CR42490 http://flybase.net/reports/FBgn0086200.html pseudogene_attribute "HDC03087, BK003543, CG42490" CR42490 16-Dec-15 2015_12 FBgn0267695 CR46031 http://flybase.net/reports/FBgn0267695.html non_protein_coding_gene CR46031 16-Dec-15 2015_12 FBgn0032022 CG14275 http://flybase.net/reports/FBgn0032022.html FBgn0047061 protein_coding_gene "BcDNA:RE73208, CT33900" CG14275 16-Dec-15 2015_12 viable FBgn0046334 en::hth en::hth http://flybase.net/reports/FBgn0046334.html engineered_fusion_gene EN-HTH 16-Dec-15 2015_12 "lethal,heat sensitive,visible" "abdominal lateral pentascolopidial chordotonal organ lch5 | embryonic stage 16,lch5 ligament attachment cell | embryonic stage 16,eye,eye disc,ectopic,head capsule,ventral,antenna,maxillary palpus,antennal foramen,leg,chaeta,third segment of antenna,distal,tibia,coxa,trochanter,femur,tarsal segment,unguis,ventral thoracic disc,wing hinge,wing,wing margin,anterior,wing vein,wing disc,labellum" FBgn0001143 gs(1)N26 grandchildless N26 http://flybase.net/reports/FBgn0001143.html gene "0007097=nuclear migration, 0045448=mitotic cell cycle, embryonic, 0007279=pole cell formation" 16-Dec-15 2015_12 "grandchildless,heat sensitive" cleavage nucleus FBgn0026661 l(2)11B9 lethal (2) 11B9 http://flybase.net/reports/FBgn0026661.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0082352 HM36 HM36 http://flybase.net/reports/FBgn0082352.html gene 16-Dec-15 2015_12 FBgn0001378 l(1)2Bj lethal (1) 2Bj http://flybase.net/reports/FBgn0001378.html gene 16-Dec-15 2015_12 "lethal,polyphasic" FBgn0067883 Mod(Prat:bw)1-4 Mod(Prat:bw)1-4 http://flybase.net/reports/FBgn0067883.html gene Mod-1-4 16-Dec-15 2015_12 FBgn0265992 CR44767 http://flybase.net/reports/FBgn0265992.html non_protein_coding_gene lincRNA.177 CR44767 16-Dec-15 2015_12 FBgn0025008 E(tkv)D2 E(tkv)D2 http://flybase.net/reports/FBgn0025008.html gene D2 16-Dec-15 2015_12 FBgn0051422 CG31422 http://flybase.net/reports/FBgn0051422.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033752 CG8569 http://flybase.net/reports/FBgn0033752.html protein_coding_gene 0008270=zinc ion binding "IPR002893=Zinc finger, MYND-type, IPR000313=PWWP domain, IPR001487=Bromodomain" CG8569 16-Dec-15 2015_12 ENSDARG00000057249(zmynd11) ENSG00000015171(ZMYND11) "viable,visible" mesothoracic tergum FBgn0004771 l(3)89Ej lethal (3) 89Ej http://flybase.net/reports/FBgn0004771.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0060396 l(3)S132301 lethal (3) S132301 http://flybase.net/reports/FBgn0060396.html gene 1323/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0034971 CG3209 http://flybase.net/reports/FBgn0034971.html protein_coding_gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity 0008152=metabolic process 0012505=endomembrane system GPAT4 IPR002123=Phospholipid/glycerol acyltransferase CG3209 16-Dec-15 2015_12 "WBGene00018657(acl-4),WBGene00011106(acl-5)" "ENSG00000138678(AGPAT9),ENSG00000158669(AGPAT6)" viable FBgn0038783 CG4367 http://flybase.net/reports/FBgn0038783.html protein_coding_gene 0019028=viral capsid "IPR004302=Chitin-binding, domain 3" CG4367 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0087017 l(3)61De lethal (3) 61De http://flybase.net/reports/FBgn0087017.html gene 16-Dec-15 2015_12 lethal FBgn0052438 SMC5 Structural maintenance of chromosomes 5 http://flybase.net/reports/FBgn0052438.html FBgn0037103 protein_coding_gene "0019789=SUMO transferase activity, 0003684=damaged DNA binding, 0016887=ATPase activity" "0007067=mitotic nuclear division, 0031000=response to caffeine, 0000070=mitotic sister chromatid segregation, 0006281=DNA repair, 0000724=double-strand break repair via homologous recombination, 0006974=cellular response to DNA damage stimulus" "0030915=Smc5-Smc6 complex, 0005634=nucleus, 0000796=condensin complex" "AAF51749, CG32438, Smc5, SMC5, CG7783, DmSMC5" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027131=Structural maintenance of chromosomes protein 5, IPR003395=RecF/RecN/SMC, N-terminal" CG32438 16-Dec-15 2015_12 YOL034W(SMC5) WBGene00016151(C27A2.1) ENSMUSG00000024943(Smc5) ENSG00000198887(SMC5) "viable,lethal,conditional,chemical sensitive,radiation sensitive" FBgn0037579 COX7AL Cytochrome c oxidase subunit 7A-like http://flybase.net/reports/FBgn0037579.html protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" 0005751=mitochondrial respiratory chain complex IV "COXK, COXJ, CG18193, VIIa, Cytochrome c oxidase polypeptide VIIa, Cytochrome c oxidase Polypeptide VIIA" "IPR003177=Cytochrome c oxidase, subunit VIIa" CG18193 16-Dec-15 2015_12 "ENSDARG00000053217(cox7a2),ENSDARG00000069464(zgc:153177),ENSDARG00000054907(cox7a2l)" "ENSXETG00000025853(COX7A2),ENSXETG00000024477(cox7a2l)" "ENSMUSG00000032330(Cox7a2),ENSMUSG00000074218(Cox7a1)" "ENSG00000112695(COX7A2),ENSG00000115944(COX7A2L)" FBgn0260248 GSd430 http://flybase.net/reports/FBgn0260248.html gene 16-Dec-15 2015_12 lethal FBgn0085819 28SrRNA-ë¬:CR41609 28S ribosomal RNA pseudogene:CR41609 http://flybase.net/reports/FBgn0085819.html FBan0041609 pseudogene_attribute CR41609 CR41609 16-Dec-15 2015_12 FBgn0264326 DNApol-ëµ255 DNA polymerase ëµ 255kD subunit http://flybase.net/reports/FBgn0264326.html "FBgn0086326, FBgn0020756, FBgn0039072" protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0003677=DNA binding, 0000166=nucleotide binding, 0008270=zinc ion binding, 0008296=3'-5'-exodeoxyribonuclease activity" "0006974=cellular response to DNA damage stimulus, 0007113=endomitotic cell cycle, 0035265=organ growth, 0022008=neurogenesis, 0006261=DNA-dependent DNA replication, 0006281=DNA repair, 0000278=mitotic cell cycle" "0008622=epsilon DNA polymerase complex, 0005634=nucleus" "BAB17608, DNApol-epsilon, DNA polymerase epsilon, CG6768, pol-epsilon, dpolepsilonp255, pl[10], lethal (3) pl10, 6768, l(3)pl10R, dpolepsilon, DNA pol epsilon, DNApolymarase E, l(3)pl10" "IPR006133=DNA-directed DNA polymerase, family B, exonuclease domain, IPR012337=Ribonuclease H-like domain, IPR006172=DNA-directed DNA polymerase, family B, IPR006134=DNA-directed DNA polymerase, family B, multifunctional domain, IPR013697=DNA polymerase epsilon, catalytic subunit A, C-terminal, IPR029703=DNA polymerase epsilon catalytic subunit" CG6768 16-Dec-15 2015_12 ENSDARG00000058533(pole) YNL262W(POL2) WBGene00009368(F33H2.5) ENSXETG00000016151(POLE) ENSMUSG00000007080(Pole) ENSG00000177084(POLE) " adult stage | male , egg stage | unfertilized egg , embryonic stage--pupal stage , adult stage | female " unfertilized egg

FBgn0004538 l(4)102EFf lethal (4) 102EFf http://flybase.net/reports/FBgn0004538.html gene l(4)19 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005538 l(3)72Df lethal (3) 72Df http://flybase.net/reports/FBgn0005538.html gene 1(3)72Df 16-Dec-15 2015_12 lethal FBgn0034110 Atg9 Autophagy-related 9 http://flybase.net/reports/FBgn0034110.html protein_coding_gene "0000045=autophagic vacuole assembly, 0009267=cellular response to starvation, 0010508=positive regulation of autophagy, 0034599=cellular response to oxidative stress, 1902350=cellular response to chloroquine, 0046330=positive regulation of JNK cascade" "0005737=cytoplasm, 0016021=integral component of membrane, 0030054=cell junction" "atg9, Autophagy-specific gene 9, ATG9, CG3615" IPR007241=Autophagy-related protein 9 CG3615 16-Dec-15 2015_12 "ENSDARG00000055292,ENSDARG00000044551(atg9a)" YDL149W(ATG9) WBGene00020706(atg-9) "ENSXETG00000011985(),ENSXETG00000019294(ATG9A)" "ENSMUSG00000033124(Atg9a),ENSMUSG00000038295(Atg9b)" "ENSG00000198925(ATG9A),ENSG00000181652" pupal stage salivary gland

"viable,visible,increased cell death" "embryonic/larval fat body,somatic clone | third instar larval stage,intestinal stem cell,chemical conditional,eye,eye disc | third instar larval stage" FBgn0000507 anon-61Fa anon-61Fa http://flybase.net/reports/FBgn0000507.html gene "doublesex cognate 61F, dsx-c61F, unnamed" 16-Dec-15 2015_12 FBgn0035617 l(3)psg2 lethal (3) persistent salivary gland 2 http://flybase.net/reports/FBgn0035617.html FBgn0025986 protein_coding_gene "0043067=regulation of programmed cell death, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007480=imaginal disc-derived leg morphogenesis" "clone 1.47, CG5146, psg2, anon-EST:Liang-1.47" CG5146 16-Dec-15 2015_12 "some die during P-stage,lethal - all die before end of P-stage,recessive,lethal,viable" "embryonic/larval salivary gland,leg" FBgn0013544 l(2)F11 lethal (2) F11 http://flybase.net/reports/FBgn0013544.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003311 sab straight abdomen http://flybase.net/reports/FBgn0003311.html gene 16-Dec-15 2015_12 "viable,male,male fertile" "abdomen,macrochaeta" FBgn0267558 CR45898 http://flybase.net/reports/FBgn0267558.html non_protein_coding_gene CR45898 16-Dec-15 2015_12 FBgn0025118 tRNA:P:3E tRNA:P:3E http://flybase.net/reports/FBgn0025118.html "FBgn0052784, FBgn0060119" tRNA_gene "0033424=CCG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR32784, chrX.trna2-ProCGG, tRNA:P:CGG:AE002566, AE002566.trna2-ProCGG, EG:EG0002.4" CR32784 16-Dec-15 2015_12 FBgn0037807 CG6293 http://flybase.net/reports/FBgn0037807.html protein_coding_gene 0008520=L-ascorbate:sodium symporter activity 0055085=transmembrane transport 0016020=membrane "IPR006043=Xanthine/uracil/vitamin C permease, IPR029949=Nucleobase-ascorbate transporter 4-related, IPR006042=Xanthine/uracil permease" CG6293 16-Dec-15 2015_12 "ENSDARG00000045792(LOC798958),ENSDARG00000052497(zgc:110789),ENSDARG00000015033(slc23a1)" "WBGene00020004(R11E3.2),WBGene00011596(T07G12.5),WBGene00011593(T07G12.2),WBGene00011595(T07G12.4),WBGene00021994(Y59E9AL.4),WBGene00008252(C51E3.6)" "ENSXETG00000020228(),ENSXETG00000016853(SLC23A2),ENSXETG00000008402(SLC23A1)" "ENSMUSG00000027340(Slc23a2),ENSMUSG00000024354(Slc23a1)" "ENSG00000089057(SLC23A2),ENSG00000170482(SLC23A1)" viable FBgn0265594 CR44421 http://flybase.net/reports/FBgn0265594.html non_protein_coding_gene CR44421 16-Dec-15 2015_12 FBgn0265815 CR44604 http://flybase.net/reports/FBgn0265815.html non_protein_coding_gene lincRNA.178 CR44604 16-Dec-15 2015_12 FBgn0083943 CG34107 http://flybase.net/reports/FBgn0083943.html "FBan0012816, FBgn0037799" protein_coding_gene CG12816 IPR026507=Uncharacterised protein family UPF0691 CG34107 16-Dec-15 2015_12 ENSMUSG00000026831(1700007K13Rik) FBgn0025639 Hmt4-20 Histone methyltransferase 4-20 http://flybase.net/reports/FBgn0025639.html FBgn0047197 protein_coding_gene 0042799=histone methyltransferase activity (H4-K20 specific) "0040029=regulation of gene expression, epigenetic, 0034772=histone H4-K20 dimethylation, 0034773=histone H4-K20 trimethylation, 0034770=histone H4-K20 methylation, 0016571=histone methylation, 0006342=chromatin silencing" "0005700=polytene chromosome, 0005720=nuclear heterochromatin, 0005634=nucleus" "Suv4-20, EG:115C2.10, histone methyltransferase 4-20, hmt4-20, Su(var)4-20, SUV4-20, dSuv4-20, Suv4.20, BcDNA:LD36415, CG13363" "IPR025790=Histone-lysine N-methyltransferase, Suvar4-20, IPR001214=SET domain" CG13363 16-Dec-15 2015_12 ENSDARG00000041081(suv420h1) ENSXETG00000010025(TTpA011k01.1) ENSMUSG00000045098(Suv420h1) ENSG00000110066(SUV420H1) "viable,suppressor of variegation,dominant,non-suppressor of variegation,fertile" DRSC18482 EK -0.263525304 -1.113695018 0.500365989 -2.469161281 -2.229715643 -0.229358561 FBgn0001661 l(1)E7 lethal (1) E7 http://flybase.net/reports/FBgn0001661.html gene l(1)E7[ts] 16-Dec-15 2015_12 "lethal,polyphasic,heat sensitive" FBgn0016973 toto toto http://flybase.net/reports/FBgn0016973.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0039482 CG14258 http://flybase.net/reports/FBgn0039482.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG14258 16-Dec-15 2015_12 viable FBgn0033427 CG1868 http://flybase.net/reports/FBgn0033427.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression "0005737=cytoplasm, 0005634=nucleus" "IPR001214=SET domain, IPR002893=Zinc finger, MYND-type" CG1868 16-Dec-15 2015_12 viable DRSC06785 K 0.884894579 -0.182451479 -0.279130319 -0.12865075 -0.80743014 -1.6166405 FBgn0033793 CG3955 http://flybase.net/reports/FBgn0033793.html protein_coding_gene CG3955 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0039059 CG13829 http://flybase.net/reports/FBgn0039059.html protein_coding_gene 0070072=vacuolar proton-transporting V-type ATPase complex assembly IPR019013=Vacuolar ATPase assembly integral membrane protein Vma21 CG13829 16-Dec-15 2015_12 viable FBgn0030460 CG2453 http://flybase.net/reports/FBgn0030460.html protein_coding_gene "0043334=2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity, 0008425=2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity" 0006744=ubiquinone biosynthetic process 0005739=mitochondrion "IPR023576=UbiE/COQ5 methyltransferase, conserved site, IPR004033=UbiE/COQ5 methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG2453 16-Dec-15 2015_12 ENSDARG00000035618(zgc:92445) YML110C(COQ5) WBGene00000765(coq-5) ENSXETG00000012228(COQ5) ENSMUSG00000041733(Coq5) ENSG00000110871(COQ5) viable FBgn0043986 Su(rst)E252 Su(rst)E252 http://flybase.net/reports/FBgn0043986.html gene 0001745=compound eye morphogenesis E252 16-Dec-15 2015_12 viable FBgn0065504 l(2)SH1201 lethal (2) SH1201 http://flybase.net/reports/FBgn0065504.html gene l(2)SH2 1201 16-Dec-15 2015_12 "lethal,recessive" FBgn0036877 CG9452 http://flybase.net/reports/FBgn0036877.html protein_coding_gene 0003993=acid phosphatase activity 0016311=dephosphorylation "0005634=nucleus, 0070062=extracellular exosome" "IPR000560=Histidine phosphatase superfamily, clade-2, IPR029630=Venom acid phosphatase Acph-1, IPR029033=Histidine phosphatase superfamily" CG9452 16-Dec-15 2015_12 FBgn0267286 CR45722 http://flybase.net/reports/FBgn0267286.html non_protein_coding_gene CR45722 16-Dec-15 2015_12 FBgn0038423 CG10317 http://flybase.net/reports/FBgn0038423.html protein_coding_gene CG10317 16-Dec-15 2015_12 viable FBgn0085249 CG34220 http://flybase.net/reports/FBgn0085249.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG34220 16-Dec-15 2015_12 FBgn0002039 l(2)37Dc lethal (2) 37Dc http://flybase.net/reports/FBgn0002039.html gene "l(2)E106, E106" 16-Dec-15 2015_12 "lethal,recessive" FBgn0003164 puff puff http://flybase.net/reports/FBgn0003164.html gene puf 16-Dec-15 2015_12 "wing,3rd posterior cell" FBgn0070040 3R-40-7 3R-40-7 http://flybase.net/reports/FBgn0070040.html gene 0008362=chitin-based embryonic cuticle biosynthetic process 16-Dec-15 2015_12 "egg,germline clone,maternal effect,embryonic/first instar larval cuticle" FBgn0069221 gl(2R)279-37 gl(2R)279-37 http://flybase.net/reports/FBgn0069221.html gene 0007379=segment specification 16-Dec-15 2015_12 "viable,terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage" "denticle belt,germline clone,maternal effect" FBgn0267872 CR46160 http://flybase.net/reports/FBgn0267872.html pseudogene_attribute CG12717-related CR46160 16-Dec-15 2015_12 FBgn0001795 l(1)Mb28 lethal (1) Mb28 http://flybase.net/reports/FBgn0001795.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing margin bristle,wing" FBgn0053490 CG33490 http://flybase.net/reports/FBgn0053490.html FBgn0036174 protein_coding_gene CG6110 CG33490 16-Dec-15 2015_12 ENSMUSG00000023931(Efhb) ENSG00000163576(EFHB) viable FBgn0262988 CG43296 http://flybase.net/reports/FBgn0262988.html protein_coding_gene CG43296 16-Dec-15 2015_12 FBgn0051606 CG31606 http://flybase.net/reports/FBgn0051606.html protein_coding_gene CG31606 16-Dec-15 2015_12 viable FBgn0085531 CG40878 http://flybase.net/reports/FBgn0085531.html FBan0040878 protein_coding_gene 16-Dec-15 2015_12 FBgn0051248 CG31248 http://flybase.net/reports/FBgn0051248.html FBgn0037474 protein_coding_gene CG2640 IPR016181=Acyl-CoA N-acyltransferase CG31248 16-Dec-15 2015_12 "viable,fertile" DRSC22722 K -0.06094311 0.507407235 -0.345191931 0.21199347 0.080595505 1.557650338 FBgn0038327 Trax Translin associated factor X http://flybase.net/reports/FBgn0038327.html protein_coding_gene "0043565=sequence-specific DNA binding, 0004521=endoribonuclease activity" 0005737=cytoplasm "Translin-associated factor X, trax, CG5063" "IPR016069=Translin, C-terminal, IPR016068=Translin, N-terminal, IPR002848=Translin" CG5063 16-Dec-15 2015_12 ENSDARG00000038995(zgc:114078) ENSXETG00000026152(tsnax) "ENSMUSG00000056820(Tsnax),ENSMUSG00000047323" ENSG00000116918(TSNAX) "female fertile,viable" FBgn0032343 CG6201 http://flybase.net/reports/FBgn0032343.html protein_coding_gene 0003940=L-iduronidase activity 0005975=carbohydrate metabolic process "IPR000514=Glycoside hydrolase, family 39, IPR013781=Glycoside hydrolase, catalytic domain, IPR017853=Glycoside hydrolase superfamily" CG6201 16-Dec-15 2015_12 ENSDARG00000062904(si:ch211-12e13.9) ENSMUSG00000033540(Idua) ENSG00000127415(IDUA) "partially lethal - majority die,some die during pupal stage" FBgn0040083 p78 p78 http://flybase.net/reports/FBgn0040083.html gene 16-Dec-15 2015_12 FBgn0262215 mir-989 mir-989 stem loop http://flybase.net/reports/FBgn0262215.html miRNA_gene 0007298=border follicle cell migration "dme-mir-989, miR-989, CR42922, lincRNA.307" CR42922 16-Dec-15 2015_12 "partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage" "eye,wing,wing margin,wing vein L2,male limited,wing vein L4,wing vein L5,wing vein,border follicle cell,somatic clone" FBgn0022814 E(faf)E254 Enhancer of faf E254 http://flybase.net/reports/FBgn0022814.html gene 16-Dec-15 2015_12 viable FBgn0085763 CR40659 http://flybase.net/reports/FBgn0085763.html FBan0040659 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0037721 CG9427 http://flybase.net/reports/FBgn0037721.html protein_coding_gene "IPR004911=Gamma interferon inducible lysosomal thiol reductase GILT, IPR012336=Thioredoxin-like fold" CG9427 16-Dec-15 2015_12 "WBGene00009514(F37H8.5),WBGene00004135(pqn-48)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037336 CG2519 http://flybase.net/reports/FBgn0037336.html protein_coding_gene CG2519 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0065913 l(2)SH0174 lethal (2) SH0174 http://flybase.net/reports/FBgn0065913.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265266 CG13639 http://flybase.net/reports/FBgn0265266.html "FBgn0039236, FBgn0066953" protein_coding_gene anon-SAGE:Wang-045 CG13639 16-Dec-15 2015_12 FBgn0033650 CG13193 http://flybase.net/reports/FBgn0033650.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG13193 16-Dec-15 2015_12 viable FBgn0034399 CG15083 http://flybase.net/reports/FBgn0034399.html FBgn0047034 protein_coding_gene BcDNA:RH17222 CG15083 16-Dec-15 2015_12 embryonic/larval hemocyte | third instar larval stage FBgn0085290 CG34261 http://flybase.net/reports/FBgn0085290.html protein_coding_gene IPR002589=Macro domain CG34261 16-Dec-15 2015_12 ENSDARG00000057426(zgc:110708) FBgn0065315 l(2)SH1929 lethal (2) SH1929 http://flybase.net/reports/FBgn0065315.html gene l(2)SH2 1929 16-Dec-15 2015_12 "lethal,recessive" FBgn0034000 CG11808 http://flybase.net/reports/FBgn0034000.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" CG11808 16-Dec-15 2015_12 ENSDARG00000033987(LOC100333300) viable FBgn0264371 CR43823 http://flybase.net/reports/FBgn0264371.html non_protein_coding_gene CR43823 16-Dec-15 2015_12 FBgn0002785 mot-28 mottled 28 http://flybase.net/reports/FBgn0002785.html gene Mot[28] 16-Dec-15 2015_12 "visible,cold sensitive" pigment cell FBgn0259558 B1250 http://flybase.net/reports/FBgn0259558.html gene 16-Dec-15 2015_12 lethal FBgn0051682 Tengl1 Testis EndoG-Like 1 http://flybase.net/reports/FBgn0051682.html "FBgn0031404, FBgn0063770" protein_coding_gene "0004520=endodeoxyribonuclease activity, 0046872=metal ion binding, 0003676=nucleic acid binding" 0005739=mitochondrion "CG17006, BcDNA:AT02809, CG31682" "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG31682 16-Dec-15 2015_12 viable FBgn0030926 psh persephone http://flybase.net/reports/FBgn0030926.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008233=peptidase activity" "0045087=innate immune response, 0006952=defense response, 0008592=regulation of Toll signaling pathway, 0006967=positive regulation of antifungal peptide biosynthetic process, 0050832=defense response to fungus, 0006508=proteolysis" 0005576=extracellular region "CG6367, Persephone, Psh, SP28, c-SP28" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG6367 16-Dec-15 2015_12 "immune response defective,viable" FBgn0005161 l(2)G156 lethal (2) G156 http://flybase.net/reports/FBgn0005161.html gene 16-Dec-15 2015_12 lethal FBgn0065717 l(2)SH0577 lethal (2) SH0577 http://flybase.net/reports/FBgn0065717.html gene l(2)SH2 0577 16-Dec-15 2015_12 "lethal,recessive" FBgn0262963 CR43274 http://flybase.net/reports/FBgn0262963.html non_protein_coding_gene lincRNA.175 CR43274 16-Dec-15 2015_12 FBgn0265812 CR44601 http://flybase.net/reports/FBgn0265812.html non_protein_coding_gene lincRNA.158 CR44601 16-Dec-15 2015_12 FBgn0017649 E(Brd)M10 Enhancer of Bearded http://flybase.net/reports/FBgn0017649.html gene 16-Dec-15 2015_12 FBgn0083260 E(smoDN)845 Enhancer of smoDN 845 http://flybase.net/reports/FBgn0083260.html gene 16-Dec-15 2015_12 FBgn0265937 CR44724 http://flybase.net/reports/FBgn0265937.html non_protein_coding_gene CR44724 16-Dec-15 2015_12 FBgn0052000 CG32000 http://flybase.net/reports/FBgn0052000.html "FBgn0047229, FBgn0062460, FBgn0064774" protein_coding_gene "0046872=metal ion binding, 0000166=nucleotide binding, 0042625=ATPase activity, coupled to transmembrane movement of ions" 0006812=cation transport 0016021=integral component of membrane "BcDNA:LD19039, BcDNA:SD17880, BcDNA:LD05303" "IPR006544=P-type ATPase, subfamily V, IPR001757=P-type ATPase, IPR023299=P-type ATPase, cytoplasmic domain N, IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR023214=HAD-like domain" CG32000 16-Dec-15 2015_12 ENSDARG00000061890(atp13a2) YOR291W(YPK9) "WBGene00012341(catp-6),WBGene00022010(catp-7),WBGene00019493(catp-5)" ENSXETG00000003447(ATP13A3) "ENSMUSG00000022533(Atp13a3),ENSMUSG00000038094(Atp13a4)" "ENSG00000133657(ATP13A3),ENSG00000127249(ATP13A4)" viable DRSC17103 IE 1.109331212 2.443208947 3.46895418 -2.100177874 -0.889555555 0.08368044 FBgn0266323 CR44988 http://flybase.net/reports/FBgn0266323.html non_protein_coding_gene CR44988 16-Dec-15 2015_12 FBgn0033948 CG12863 http://flybase.net/reports/FBgn0033948.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0008168=methyltransferase activity" "IPR019369=Protein-lysine N-methyltransferase Efm5, IPR017921=Zinc finger, CTCHY-type, IPR001594=Zinc finger, DHHC-type, palmitoyltransferase, IPR001878=Zinc finger, CCHC-type" CG12863 16-Dec-15 2015_12 ENSDARG00000018810(zgc:172248) WBGene00009352(F33A8.4) ENSXETG00000000960(ZCCHC4) ENSMUSG00000029179(Zcchc4) ENSG00000168228(ZCCHC4) FBgn0032598 ChLD3 ChLD3 http://flybase.net/reports/FBgn0032598.html protein_coding_gene "0008061=chitin binding, 0016810=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds" "0006030=chitin metabolic process, 0005975=carbohydrate metabolic process" 0005576=extracellular region "CG17905, DmChLD3, DmCDA3" "IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR002509=NodB homology domain, IPR002557=Chitin binding domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG17905 16-Dec-15 2015_12 FBgn0015419 l(1)16Ca lethal (1) 16Ca http://flybase.net/reports/FBgn0015419.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037577 CG7443 http://flybase.net/reports/FBgn0037577.html protein_coding_gene CG7443 16-Dec-15 2015_12 viable FBgn0082331 HM805 HM805 http://flybase.net/reports/FBgn0082331.html gene 16-Dec-15 2015_12 FBgn0060318 l(3)S147402 lethal (3) S147402 http://flybase.net/reports/FBgn0060318.html gene 1474/02 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0260871 CG42581 http://flybase.net/reports/FBgn0260871.html protein_coding_gene CG42581 16-Dec-15 2015_12 FBgn0036368 CG10738 http://flybase.net/reports/FBgn0036368.html protein_coding_gene "0005524=ATP binding, 0004383=guanylate cyclase activity, 0004872=receptor activity, 0004672=protein kinase activity" "0006182=cGMP biosynthetic process, 0045792=negative regulation of cell size, 0007165=signal transduction, 0045931=positive regulation of mitotic cell cycle, 0007030=Golgi organization, 0019934=cGMP-mediated signaling, 0006468=protein phosphorylation, 0008284=positive regulation of cell proliferation" "0005886=plasma membrane, 0005887=integral component of plasma membrane" GYC "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR011645=Haem NO binding associated, IPR028082=Periplasmic binding protein-like I, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828=Receptor, ligand binding region, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase" CG10738 16-Dec-15 2015_12 viable FBgn0035923 CG6511 http://flybase.net/reports/FBgn0035923.html protein_coding_gene CG6511 16-Dec-15 2015_12 ENSDARG00000019834(LOC566404) ENSXETG00000022608() ENSMUSG00000039990(2700050L05Rik) ENSG00000107938(C10orf137) FBgn0053687 CG33687 http://flybase.net/reports/FBgn0053687.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33687 16-Dec-15 2015_12 FBgn0261932 CG42798 http://flybase.net/reports/FBgn0261932.html protein_coding_gene IPR002350=Kazal domain CG42798 16-Dec-15 2015_12 FBgn0058143 CG40143 http://flybase.net/reports/FBgn0058143.html FBan0040143 protein_coding_gene 16-Dec-15 2015_12 FBgn0002340 l(3)87Bi lethal (3) 87Bi http://flybase.net/reports/FBgn0002340.html gene "l(3)ck21, ck21" 16-Dec-15 2015_12 lethal FBgn0044814 T:nt1-boss nt1 epitope of boss http://flybase.net/reports/FBgn0044814.html engineered_tag T:boss 16-Dec-15 2015_12 FBgn0259293 EP-M71 http://flybase.net/reports/FBgn0259293.html gene 16-Dec-15 2015_12 visible "wing hair,wing vein" FBgn0065934 l(2)SH0127 lethal (2) SH0127 http://flybase.net/reports/FBgn0065934.html gene l(2)SH2 0127 16-Dec-15 2015_12 "lethal,recessive" FBgn0037895 CG6723 http://flybase.net/reports/FBgn0037895.html protein_coding_gene 0008507=sodium:iodide symporter activity 0055085=transmembrane transport 0016020=membrane dSLC5A8 "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG6723 16-Dec-15 2015_12 YHL016C(DUR3) WBGene00014092(ZK822.5) viable FBgn0011156 l(1)Q234 lethal (1) Q234 http://flybase.net/reports/FBgn0011156.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0036146 CG14141 http://flybase.net/reports/FBgn0036146.html FBgn0062434 protein_coding_gene "BcDNA:RH33338, CT33742" "IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG14141 16-Dec-15 2015_12 WBGene00043050(oig-4) viable FBgn0032703 CG10343 http://flybase.net/reports/FBgn0032703.html FBgn0062230 protein_coding_gene anon-WO0118547.123 "IPR006575=RWD domain, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG10343 16-Dec-15 2015_12 ENSDARG00000068256(zgc:103545) ENSXETG00000019065(BC080441.1) ENSMUSG00000031568(Rwdd4a) ENSG00000182552(RWDD4) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0013655 ms(2)ry2 ms(2)ry2 http://flybase.net/reports/FBgn0013655.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0259946 Ttd12 TRPL translocation defect 12 http://flybase.net/reports/FBgn0259946.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011145 l(1)Q221 lethal (1) Q221 http://flybase.net/reports/FBgn0011145.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0034045 CG8249 http://flybase.net/reports/FBgn0034045.html protein_coding_gene 0005355=glucose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR003663=Sugar/inositol transporter, IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site" CG8249 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0051354 Hsp70Bbb Hsp70Bbb http://flybase.net/reports/FBgn0051354.html FBgn0040549 protein_coding_gene "0035080=heat shock-mediated polytene chromosome puffing, 0001666=response to hypoxia, 0009408=response to heat" "0005811=lipid particle, 0005875=microtubule associated complex" "Hsp70B, hsp70, heat-shock protein 70, HSP70, CG31354, heat shock protein 70, CG5834, Hsp70Bb, dHsp70, Dm-hsp70, Hsp70, Hsp-70, hsp70B, HSP70Bbb, hsp70Bb-prime" "IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site, IPR013126=Heat shock protein 70 family" CG5834 16-Dec-15 2015_12 neuroanatomy defective "Kenyon cell,adult mushroom body" FBgn0003032 pads pads http://flybase.net/reports/FBgn0003032.html gene 16-Dec-15 2015_12 wing FBgn0011291 Taf11 TBP-associated factor 11 http://flybase.net/reports/FBgn0011291.html protein_coding_gene "0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" "0006355=regulation of transcription, DNA-templated, 0006367=transcription initiation from RNA polymerase II promoter" "0005634=nucleus, 0005669=transcription factor TFIID complex" "TAF[[II]]30beta, dTAFII30, dTAF[[II]]30beta, TAF1, TFIID-p28beta, dTAFII30 beta, Taf30beta, Taf[[II]]30beta, TAF30b, TAF[II]30beta, TAF11, TAF, TBP-associated factor 30kD subunit beta, dTAF[[II]]30, d30beta, TFIID, dTAFII30beta, TBP-associated factor, CG4079, TFIID 28 beta, TAF30beta, TAF[[II]]" "IPR006809=TAFII28-like protein, IPR009072=Histone-fold" CG4079 16-Dec-15 2015_12 ENSDARG00000037855(zgc:92784) "WBGene00006393(taf-11.1),WBGene00006394(taf-11.2)" ENSMUSG00000024218(Taf11) "ENSG00000064995(TAF11),ENSG00000185041" "partially lethal - majority die,some die during pupal stage" FBgn0263080 CG43348 http://flybase.net/reports/FBgn0263080.html protein_coding_gene "chr2L_1199311_1199719.0, CG43180" CG43348 16-Dec-15 2015_12 FBgn0060544 l(3)S099006 lethal (3) S099006 http://flybase.net/reports/FBgn0060544.html gene 0990/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0038446 CG14903 http://flybase.net/reports/FBgn0038446.html protein_coding_gene 0004045=aminoacyl-tRNA hydrolase activity "IPR023476=Peptidyl-tRNA hydrolase II domain, IPR002833=Peptidyl-tRNA hydrolase, PTH2" CG14903 16-Dec-15 2015_12 ENSDARG00000016122(si:dkey-34f16.5) WBGene00050885(Y94H6A.12) ENSXETG00000021176(C2orf79) ENSMUSG00000073240 ENSG00000184924(PTRHD1) viable FBgn0032677 CG5790 http://flybase.net/reports/FBgn0032677.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0005524=ATP binding" "0006909=phagocytosis, 0008360=regulation of cell shape, 0006468=protein phosphorylation" 0031431=Dbf4-dependent protein kinase complex CDC 7-related "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG5790 16-Dec-15 2015_12 ENSDARG00000023584(cdc7) YDL017W(CDC7) WBGene00016421(C34G6.5) ENSXETG00000023034(cdc7) ENSMUSG00000029283(Cdc7) ENSG00000097046(CDC7) "viable,fertile" FBgn0265665 CR44472 http://flybase.net/reports/FBgn0265665.html non_protein_coding_gene CR44472 16-Dec-15 2015_12 FBgn0037031 CG11456 http://flybase.net/reports/FBgn0037031.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG11456 16-Dec-15 2015_12 viable FBgn0014060 Su(tor)2-87 Su(tor)2-87 http://flybase.net/reports/FBgn0014060.html gene 16-Dec-15 2015_12 FBgn0033512 CG12902 http://flybase.net/reports/FBgn0033512.html FBgn0063344 protein_coding_gene BcDNA:AT11401 CG12902 16-Dec-15 2015_12 viable FBgn0086346 ALiX ALG-2 interacting protein X http://flybase.net/reports/FBgn0086346.html "FBgn0065037, FBgn0039541" protein_coding_gene "0004843=ubiquitin-specific protease activity, 0004871=signal transducer activity" "0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0046330=positive regulation of JNK cascade, 0030041=actin filament polymerization, 0048133=male germ-line stem cell asymmetric division, 0000281=mitotic cytokinesis, 0048132=female germ-line stem cell asymmetric division, 1990182=exosomal secretion, 0006915=apoptotic process" "0005768=endosome, 0005813=centrosome, 0070938=contractile ring, 0030496=midbody, 0045171=intercellular bridge" "alix, ALIX, ALG-2 interacting protein 1, apoptosis linked gene 2 interacting X, Aip1, Snf7, CG12876, DAIP1, Alix, AIP1" "IPR004328=BRO1 domain, IPR025304=ALIX V-shaped domain" CG12876 16-Dec-15 2015_12 ENSDARG00000025269(pdcd6ip) YOR275C(RIM20) WBGene00007010(alx-1) ENSXETG00000017906() ENSMUSG00000032504(Pdcd6ip) ENSG00000170248(PDCD6IP) FBgn0053963 CR33963 http://flybase.net/reports/FBgn0053963.html FBgn0063277 non_protein_coding_gene BcDNA:GH04518 CR33963 16-Dec-15 2015_12 FBgn0259201 CG42305 http://flybase.net/reports/FBgn0259201.html protein_coding_gene Dromel_CG17325_FBtr0081102_uORF CG42305 16-Dec-15 2015_12 FBgn0023477 Taldo Transaldolase http://flybase.net/reports/FBgn0023477.html FBgn0034934 protein_coding_gene 0004801=sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity "0005975=carbohydrate metabolic process, 0009052=pentose-phosphate shunt, non-oxidative branch, 0006098=pentose-phosphate shunt" 0005737=cytoplasm "Tal, tal, TA, CG2827, Transaldolase, transaldolase, CT9666, 154176_at" "IPR004730=Transaldolase type 1, IPR013785=Aldolase-type TIM barrel, IPR018225=Transaldolase, active site, IPR001585=Transaldolase" CG2827 16-Dec-15 2015_12 ENSDARG00000012256(taldo1) "YLR354C(TAL1),YGR043C(NQM1)" WBGene00021286(Y24D9A.8) ENSXETG00000001671(taldo1) ENSMUSG00000025503(Taldo1) ENSG00000177156(TALDO1) "viable,body color defective" mesothoracic tergum FBgn0022702 Cht2 Chitinase 2 http://flybase.net/reports/FBgn0022702.html protein_coding_gene 0004568=chitinase activity "0005975=carbohydrate metabolic process, 0006036=cuticle chitin catabolic process" "CG2054, DmCHT2, CHT2, cht2" "IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR001579=Glycoside hydrolase, chitinase active site, IPR029070=Chitinase insertion domain" CG2054 16-Dec-15 2015_12 YDR371W(CTS2) "viable,body color defective" "embryonic/larval dorsal trunk,dorsal trunk primordium | embryonic stage 15,mesothoracic tergum" FBgn0259441 EP-87 http://flybase.net/reports/FBgn0259441.html gene 16-Dec-15 2015_12 visible wing vein FBgn0005489 l(1)ts2009 lethal (1) ts2009 http://flybase.net/reports/FBgn0005489.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0041246 Gr32a Gustatory receptor 32a http://flybase.net/reports/FBgn0041246.html FBgn0032344 protein_coding_gene 0008527=taste receptor activity "0008049=male courtship behavior, 0050909=sensory perception of taste" 0016021=integral component of membrane "GR32a, 32D1, Gr32D1, GR32D1, Gr32d, CG14916, 32D.1, Gr32A, GR32D.1, Gustatory receptor 32D.1" IPR013604=7TM chemoreceptor CG14916 16-Dec-15 2015_12 "courtship behavior defective,male,viable,behavior defective,male fertile,female fertile,semidominant" FBgn0046120 E(To)5 E(To)5 http://flybase.net/reports/FBgn0046120.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086074 snoRNA:Me18S-A1806 http://flybase.net/reports/FBgn0086074.html snoRNA_gene "Me18S-Am1806, Me18S-A1806-RA, CR34703" CR34703 16-Dec-15 2015_12 FBgn0259592 B0540 http://flybase.net/reports/FBgn0259592.html gene 16-Dec-15 2015_12 visible "macrochaeta,supernumerary" FBgn0021836 l(2)k15617 lethal (2) k15617 http://flybase.net/reports/FBgn0021836.html gene l(2)15617 16-Dec-15 2015_12 "lethal,recessive" FBgn0069954 CG41066 http://flybase.net/reports/FBgn0069954.html FBan0041066 protein_coding_gene 16-Dec-15 2015_12 FBgn0037556 CG9636 http://flybase.net/reports/FBgn0037556.html protein_coding_gene "IPR009060=UBA-like, IPR003892=Ubiquitin system component Cue" CG9636 16-Dec-15 2015_12 ENSDARG00000039365(cuedc2) ENSXETG00000014207(CUEDC2) ENSMUSG00000036748(Cuedc2) ENSG00000107874(CUEDC2) viable FBgn0039408 CG14551 http://flybase.net/reports/FBgn0039408.html protein_coding_gene IPR029488=KIAA1430 homologue CG14551 16-Dec-15 2015_12 viable FBgn0014949 btn buttonless http://flybase.net/reports/FBgn0014949.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG5264, btn/MEOX, Buttonless, BTN, 1261/13" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain" CG5264 16-Dec-15 2015_12 "ENSMUSG00000051038(Rhox11),ENSMUSG00000053909(Rhox10)" " embryonic stage -- adult stage , embryonic stage | stage >=11 " dorsal neurohemal organ

"viable,partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,dorsal neurohemal organ,abdominal transverse nerve,transverse nerve & prothoracic segment,transverse nerve & mesothoracic segment,transverse nerve & metathoracic segment" FBgn0260390 CG42516 http://flybase.net/reports/FBgn0260390.html FBgn0033267 protein_coding_gene Dromel_CG11508_FBtr0088817_uORF "IPR019481=Transcription factor TFIIIC, tau55-related" CG42516 16-Dec-15 2015_12 FBgn0030872 Ucp4A Ucp4A http://flybase.net/reports/FBgn0030872.html protein_coding_gene "0017077=oxidative phosphorylation uncoupler activity, 0022857=transmembrane transporter activity" "0006839=mitochondrial transport, 0015992=proton transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "dmUCP4a, DmUCP4A, ucp4a, CG6492, UCP4A, Ucp4a" "IPR002030=Mitochondrial brown fat uncoupling protein, IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG6492 16-Dec-15 2015_12 ENSDARG00000042873(slc25a27) WBGene00006729(ucp-4) ENSXETG00000016256(Q5M8V4_XENTR) ENSMUSG00000023912(Slc25a27) ENSG00000153291(SLC25A27) viable FBgn0001667 l(1)EN2 lethal (1) from Eugene Nonautonomous 2 http://flybase.net/reports/FBgn0001667.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010734 l(3)01029 lethal (3) 01029 http://flybase.net/reports/FBgn0010734.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065986 iab-4-1.s iab-4-1.s http://flybase.net/reports/FBgn0065986.html gene 4-1.s 16-Dec-15 2015_12 FBgn0267312 CR45748 http://flybase.net/reports/FBgn0267312.html non_protein_coding_gene CR45748 16-Dec-15 2015_12 FBgn0030900 Him Holes in muscle http://flybase.net/reports/FBgn0030900.html protein_coding_gene 0048635=negative regulation of muscle organ development "Him, CG15064, Holes in Muscles, holes-in-muscle, him" CG15064 16-Dec-15 2015_12 "lethal,partially,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval muscle system,trichogen cell" FBgn0042177 CG32164 http://flybase.net/reports/FBgn0042177.html FBgn0036647 protein_coding_gene 0008536=Ran GTPase binding 0006886=intracellular protein transport "CG18219, CG18860, unnamed" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain" CG32164 16-Dec-15 2015_12 ENSXETG00000014621(IPO4) ENSMUSG00000002319(Ipo4) ENSG00000196497(IPO4) FBgn0021788 l(2)rQ029 lethal (2) rQ029 http://flybase.net/reports/FBgn0021788.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052453 CG32453 http://flybase.net/reports/FBgn0052453.html protein_coding_gene CG32453 16-Dec-15 2015_12 FBgn0086079 snoRNA:Me28S-A774a http://flybase.net/reports/FBgn0086079.html snoRNA_gene "Me28S-Am774a, Dm_28S.004, DmU18adj, CR34708, Me28S-A774a(DmU18)" CR34708 16-Dec-15 2015_12 FBgn0035234 CG12003 http://flybase.net/reports/FBgn0035234.html protein_coding_gene CG12003 16-Dec-15 2015_12 FBgn0031660 mRpL28 mitochondrial ribosomal protein L28 http://flybase.net/reports/FBgn0031660.html protein_coding_gene 0003735=structural constituent of ribosome "0032543=mitochondrial translation, 0006412=translation" 0005762=mitochondrial large ribosomal subunit "ecdysteroid regulated 16kd protein, CG3782, MRP-L28" IPR026569=Ribosomal protein L28/L24 CG3782 16-Dec-15 2015_12 ENSDARG00000057805(mrpl28) WBGene00020796(T25D3.2) ENSXETG00000011564(MRPL28) ENSMUSG00000024181(Mrpl28) ENSG00000086504(MRPL28) "viable,visible" trichogen cell FBgn0067398 Su(2)E Su(2)E http://flybase.net/reports/FBgn0067398.html gene 16-Dec-15 2015_12 FBgn0265470 CR44363 http://flybase.net/reports/FBgn0265470.html non_protein_coding_gene CR44363 16-Dec-15 2015_12 FBgn0060979 l(3)S028614 lethal (3) S028614 http://flybase.net/reports/FBgn0060979.html gene 0286/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031252 CG13690 http://flybase.net/reports/FBgn0031252.html protein_coding_gene "0004523=RNA-DNA hybrid ribonuclease activity, 0003723=RNA binding" 0016070=RNA metabolic process "IPR024567=Ribonuclease HII/HIII domain, IPR023160=Ribonuclease HII, helix-loop-helix cap domain, IPR012337=Ribonuclease H-like domain, IPR001352=Ribonuclease HII/HIII, IPR004649=Ribonuclease H2, subunit A" CG13690 16-Dec-15 2015_12 ENSDARG00000018891(rnaseh2a) YNL072W(RNH201) WBGene00004383(rnh-2) ENSXETG00000004762(rnaseh2a) ENSMUSG00000052926(Rnaseh2a) ENSG00000104889(RNASEH2A) viable DRSC00359 K -0.025759152 -0.501212145 -0.374430568 0.58839821 2.458803346 0.484176156 FBgn0011209 dbf double fault http://flybase.net/reports/FBgn0011209.html gene "0007283=spermatogenesis, 0051276=chromosome organization, 0007140=male meiosis" ms(2)04818 16-Dec-15 2015_12 "male sterile,recessive,meiotic cell cycle defective" "Y chromosome loop,spermatid,Nebenkern" FBgn0028509 CenG1A Centaurin gamma 1A http://flybase.net/reports/FBgn0028509.html "FBgn0027879, FBgn0032534, FBgn0040976, FBgn0051811" protein_coding_gene "0005096=GTPase activator activity, 0003924=GTPase activity, 0005525=GTP binding" "0043547=positive regulation of GTPase activity, 0043087=regulation of GTPase activity, 0072375=medium-term memory" "CG16867, CenG1A, Centaurin gamma, ceng1A, cenG1a, CG16866, CG31811, cenG, centaurin gamma 1A, CG7982, cenG1A, unnamed, centaurin gamma-1A, BG:DS08220.1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR001164=Arf GTPase activating protein, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG31811 16-Dec-15 2015_12 "ENSDARG00000062123(LOC100148154),ENSDARG00000061117(zgc:153779)" WBGene00000566(cnt-2) "ENSXETG00000003280(),ENSXETG00000009661(AGAP2)" "ENSMUSG00000055013(Agap1),ENSMUSG00000023353(Agap3),ENSMUSG00000025422(Agap2)" "ENSG00000133612(AGAP3),ENSG00000157985(AGAP1),ENSG00000135439(AGAP2)" "viable,fertile,developmental rate defective" FBgn0019844 anon-XXIV anon-XXIV http://flybase.net/reports/FBgn0019844.html gene XXIV 16-Dec-15 2015_12 FBgn0036861 CG14089 http://flybase.net/reports/FBgn0036861.html protein_coding_gene IPR008160=Collagen triple helix repeat CG14089 16-Dec-15 2015_12 viable FBgn0024673 l(2)k00607 lethal (2) k00607 http://flybase.net/reports/FBgn0024673.html gene 7-Jun 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0261790 SmE Small ribonucleoprotein particle protein SmE http://flybase.net/reports/FBgn0261790.html "FBgn0031962, FBgn0064937, FBgn0022966" protein_coding_gene "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus, 0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex" "dE, snRNPE, CG18591, BcDNA:GM19936, E, E-Sm" "IPR010920=LSM domain, IPR027078=Small nuclear ribonucleoprotein E, IPR001163=LSM domain, eukaryotic/archaea-type" CG18591 16-Dec-15 2015_12 ENSDARG00000033175(snrpe) YOR159C(SME1) WBGene00004919(snr-6) ENSXETG00000004471(snrpe) ENSG00000182004(SNRPE) FBgn0267618 CR45956 http://flybase.net/reports/FBgn0267618.html non_protein_coding_gene CR45956 16-Dec-15 2015_12 FBgn0267398 Yeti Yeti http://flybase.net/reports/FBgn0267398.html "FBgn0058218, FBgn0063681, FBgn0043842, FBgn0002063" protein_coding_gene 0019894=kinesin binding "0051569=regulation of histone H3-K4 methylation, 0010032=meiotic chromosome condensation, 0051570=regulation of histone H3-K9 methylation, 0051276=chromosome organization, 2000615=regulation of histone H3-K9 acetylation, 0007076=mitotic chromosome condensation" "0005634=nucleus, 0005700=polytene chromosome" "l(2)41Aa, GroupI, BEST:GH01620, l(2R)EMS-31, l(2)EMS31, 41Aa, lethal (2) 41Aa, CG40218, BcDNA:RE36623, l(2R)B" "IPR027124=SWR1-complex protein 5/Craniofacial development protein, IPR011421=BCNT-C domain" CG40218 16-Dec-15 2015_12 ENSDARG00000056639(si:dkey-6e12.6) WBGene00009565(F39H11.1) ENSMUSG00000031954(Cfdp1) ENSG00000153774(CFDP1) DRSC21138 IEK 2.284178342 0.477119361 1.298167897 -2.48881761 0.900098649 2.235449126 FBgn0259152 Clbn Caliban http://flybase.net/reports/FBgn0259152.html "FBgn0069903, FBgn0039281" protein_coding_gene 0006611=protein export from nucleus "CG11847, Clbn" "IPR008532=Domain of unknown function DUF814, IPR021846=Domain of unknown function DUF3441" CG11847 16-Dec-15 2015_12 YPL009C() WBGene00022350(Y82E9BR.18) ENSMUSG00000020982(Sdccag1) ENSG00000165525(NEMF) FBgn0259640 B2035 http://flybase.net/reports/FBgn0259640.html gene 16-Dec-15 2015_12 visible wing FBgn0013390 anon-1Ba anon-1Ba http://flybase.net/reports/FBgn0013390.html gene T7 16-Dec-15 2015_12 embryonic stage | 0-12 hr FBgn0051777 CG31777 http://flybase.net/reports/FBgn0051777.html "FBgn0031565, FBgn0063620" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity BEST:RH19272 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG31777 16-Dec-15 2015_12 viable FBgn0260109 2L3193 http://flybase.net/reports/FBgn0260109.html gene "0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0010059 M(2)28 M(2)28 http://flybase.net/reports/FBgn0010059.html gene M[[28]] 16-Dec-15 2015_12 FBgn0020888 Su(osk)P59 Suppressor of oskar P59 http://flybase.net/reports/FBgn0020888.html gene P59 16-Dec-15 2015_12 FBgn0030706 CG8909 http://flybase.net/reports/FBgn0030706.html protein_coding_gene "0005509=calcium ion binding, 0005041=low-density lipoprotein receptor activity" "yolkless-like, CT25574, Dm CG8909" "IPR000033=LDLR class B repeat, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR011042=Six-bladed beta-propeller, TolB-like, IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR001881=EGF-like calcium-binding domain" CG8909 16-Dec-15 2015_12 ENSDARG00000063640 WBGene00008779(F14B4.1) ENSXETG00000005091(LRP4) ENSMUSG00000027253(Lrp4) ENSG00000134569(LRP4) "lethal,viable" embryonic/larval brain FBgn0263493 CR43482 http://flybase.net/reports/FBgn0263493.html pseudogene_attribute CR43482 16-Dec-15 2015_12 FBgn0082911 ë_-Spec::Actn ë_-Spec::Actn http://flybase.net/reports/FBgn0082911.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0045761 CHKov1 CHKov1 http://flybase.net/reports/FBgn0045761.html "FBgn0003232, FBgn0039327" protein_coding_gene "refractory to sigma D, BcDNA:GH03753, ref(3)D, CG10618" "IPR015897=CHK kinase-like, IPR000477=Reverse transcriptase domain, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR005135=Endonuclease/exonuclease/phosphatase" CG10618 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" "chemical resistant,viable,visible" "trichogen cell,tormogen cell" FBgn0262837 CG43201 http://flybase.net/reports/FBgn0262837.html protein_coding_gene MIP03715 CG43201 16-Dec-15 2015_12 FBgn0267066 CR45510 http://flybase.net/reports/FBgn0267066.html non_protein_coding_gene CR45510 16-Dec-15 2015_12 FBgn0035398 Cht7 Cht7 http://flybase.net/reports/FBgn0035398.html protein_coding_gene "0008061=chitin binding, 0004568=chitinase activity, 0008201=heparin binding" "0005975=carbohydrate metabolic process, 0006032=chitin catabolic process" 0005576=extracellular region "DmCHT7, CG1869" "IPR011583=Chitinase II, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR002557=Chitin binding domain, IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain, IPR001579=Glycoside hydrolase, chitinase active site" CG1869 16-Dec-15 2015_12 WBGene00000503(cht-1) viable FBgn0066340 mmp mampus http://flybase.net/reports/FBgn0066340.html gene "0007611=learning or memory, 0008355=olfactory learning" Mampus 16-Dec-15 2015_12 memory defective FBgn0000566 Eip55E Eip55E http://flybase.net/reports/FBgn0000566.html protein_coding_gene "0004123=cystathionine gamma-lyase activity, 0030170=pyridoxal phosphate binding, 0003824=catalytic activity" "0000096=sulfur amino acid metabolic process, 0006750=glutathione biosynthetic process" "ecdysone induced protein 55E, EIP40, Eip55BD, CG5345, LD22255, Eip40, Ecdysone-induced protein 40kD, Ecdysone-induced polypeptide 40kD" "IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase, IPR000277=Cys/Met metabolism, pyridoxal phosphate-dependent enzyme" CG5345 16-Dec-15 2015_12 ENSDARG00000032206(cthl) YAL012W(CYS3) "WBGene00022856(cth-2),WBGene00009048(cth-1)" ENSXETG00000011183(cth) ENSMUSG00000028179(Cth) ENSG00000116761(CTH) " larval stage | third instar , larval stage " " embryonic/larval salivary gland

, lymph gland

, embryonic/larval fat body

" "viable,fertile" FBgn0014031 Spat Serine pyruvate aminotransferase http://flybase.net/reports/FBgn0014031.html protein_coding_gene "0008453=alanine-glyoxylate transaminase activity, 0004760=serine-pyruvate transaminase activity" 0009436=glyoxylate catabolic process "0005759=mitochondrial matrix, 0005777=peroxisome, 0005811=lipid particle" "Dm-Spat, serine pyruvate aminotransferase, spa, CG3926, spat" "IPR024169=Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR020578=Aminotransferase class-V, pyridoxal-phosphate binding site, IPR000192=Aminotransferase class V domain" CG3926 16-Dec-15 2015_12 "ENSDARG00000052099(agxtl),ENSDARG00000018478(agxt)" YFL030W(AGX1) WBGene00011767(T14D7.1) ENSXETG00000012149(agxt) ENSMUSG00000026272(Agxt) ENSG00000172482(AGXT) viable FBgn0031637 mxt mextli http://flybase.net/reports/FBgn0031637.html "FBgn0046805, FBtr0077409, FBpp0077100, FBtr0077410, FBpp0077101, FBtr0077411, FBpp0077102" protein_coding_gene "0008190=eukaryotic initiation factor 4E binding, 0003743=translation initiation factor activity" "0036099=female germ-line stem cell maintenance, 1901190=regulation of formation of translation initiation ternary complex, 0046331=lateral inhibition, 0045727=positive regulation of translation" "0034518=RNA cap binding complex, 0005737=cytoplasm" "Mextli, cg2950, CG2950, BcDNA:GH06479" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1, IPR016021=MIF4G-like domain" CG2950 16-Dec-15 2015_12 "female semi-fertile,embryonic/larval segmentation phenotype,viable,visible" "embryonic abdominal segment,female germline cell,embryonic thoracic segment,chaeta,supernumerary" FBgn0261446 CG13377 http://flybase.net/reports/FBgn0261446.html "FBgn0040369, FBgn0029517, FBgn0070000" protein_coding_gene 0003858=3-hydroxybutyrate dehydrogenase activity "0008152=metabolic process, 0016319=mushroom body development, 0042048=olfactory behavior, 0002121=inter-male aggressive behavior" "EG:BACR37P7.9, BG01596" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG13377 16-Dec-15 2015_12 FBgn0036571 Strumpellin Strumpellin http://flybase.net/reports/FBgn0036571.html protein_coding_gene 0071203=WASH complex "p118, CG12272" "IPR019393=WASH complex, subunit strumpellin" CG12272 16-Dec-15 2015_12 ENSDARG00000017190(zgc:55908) WBGene00020259(T05E7.3) ENSXETG00000017490(BC075486.1) ENSMUSG00000022350(E430025E21Rik) ENSG00000164961(KIAA0196) "partially lethal - majority die,visible" mesothoracic tergum FBgn0263511 Vsx1 Visual system homeobox 1 ortholog http://flybase.net/reports/FBgn0263511.html "FBgn0029775, FBgn0026559" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0000122=negative regulation of transcription from RNA polymerase II promoter, 2000179=positive regulation of neural precursor cell proliferation, 0006909=phagocytosis, 0001748=optic lobe placode development" 0005634=nucleus "Dchx1, Vsx-1, Chx1, DVSX1, dChx1, dVsx1, DChx1, lincRNA.S8688, CG4136" "IPR023339=CVC domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG4136 16-Dec-15 2015_12 FBgn0010842 l(3)77CDf lethal (3) 77CDf http://flybase.net/reports/FBgn0010842.html gene l(3)04521 16-Dec-15 2015_12 "lethal,recessive" FBgn0031393 CG15382 http://flybase.net/reports/FBgn0031393.html FBgn0047140 protein_coding_gene BcDNA:RE26473 CG15382 16-Dec-15 2015_12 viable FBgn0264446 CR43864 http://flybase.net/reports/FBgn0264446.html non_protein_coding_gene CR43864 16-Dec-15 2015_12 FBgn0026220 l(3)04704b lethal (3) 04704b http://flybase.net/reports/FBgn0026220.html gene l(3)04704 16-Dec-15 2015_12 lethal FBgn0031091 Phf7 PHD finger protein 7 ortholog http://flybase.net/reports/FBgn0031091.html protein_coding_gene "0008270=zinc ion binding, 0042393=histone binding" 0019100=male germ-line sex determination 0005700=polytene chromosome CG9576 "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type" CG9576 16-Dec-15 2015_12 ENSG00000010318(PHF7) "viable,male semi-sterile,female fertile,male fertile,visible" "male germline stem cell,germline clone,spermatocyte,spermatocyte cell spectrosome,trichogen cell" FBgn0031251 CG4213 http://flybase.net/reports/FBgn0031251.html protein_coding_gene CG4213 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0264266 CR43766 http://flybase.net/reports/FBgn0264266.html non_protein_coding_gene CR43766 16-Dec-15 2015_12 FBgn0065706 l(2)SH0612 lethal (2) SH0612 http://flybase.net/reports/FBgn0065706.html gene l(2)SH2 0612 16-Dec-15 2015_12 "lethal,recessive" FBgn0050501 CG30501 http://flybase.net/reports/FBgn0050501.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003593 Su(var)3-2 Suppressor of variegation 3-2 http://flybase.net/reports/FBgn0003593.html gene Su-var(3)2 16-Dec-15 2015_12 "suppressor of variegation,dominant,viable,fertile" FBgn0259844 Su(Ste):CR42413 Su(Ste):CR42413 http://flybase.net/reports/FBgn0259844.html non_protein_coding_gene CR42413 CR42413 16-Dec-15 2015_12 FBgn0040172 l(1)G0347 lethal (1) G0347 http://flybase.net/reports/FBgn0040172.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,female sterile" FBgn0005045 E(var)36AE Enhancer of variegation 36AE http://flybase.net/reports/FBgn0005045.html gene E(var)36A-E 16-Dec-15 2015_12 FBgn0014873 Pt4 Pt4 http://flybase.net/reports/FBgn0014873.html gene 16-Dec-15 2015_12 FBgn0023434 l(2)21Bf lethal (2) 21Bf http://flybase.net/reports/FBgn0023434.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0039754 CG9747 http://flybase.net/reports/FBgn0039754.html protein_coding_gene 0017105=acyl-CoA delta11-desaturase activity "0055114=oxidation-reduction process, 0006629=lipid metabolic process" "IPR005804=Fatty acid desaturase domain, IPR015876=Fatty acid desaturase, type 1, core" CG9747 16-Dec-15 2015_12 YGL055W(OLE1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267596 CR45934 http://flybase.net/reports/FBgn0267596.html pseudogene_attribute CG40968 CR45934 16-Dec-15 2015_12 FBgn0265495 BG01971 http://flybase.net/reports/FBgn0265495.html gene 16-Dec-15 2015_12 FBgn0025749 l(3)95Ax lethal (3) 95Ax http://flybase.net/reports/FBgn0025749.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013771 Cyp6a9 Cytochrome P450-6a9 http://flybase.net/reports/FBgn0013771.html protein_coding_gene "0020037=heme binding, 0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity" "0017143=insecticide metabolic process, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "6a9, P450, cytochrome P450 related AF4, Cyt-P450-rAF4, CYP6A9, P-450, CG10246" "IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450" CG10246 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" adult stage viable FBgn0051313 CG31313 http://flybase.net/reports/FBgn0051313.html FBgn0047056 protein_coding_gene 0004869=cysteine-type endopeptidase inhibitor activity BcDNA:RH02566 "IPR000010=Cystatin domain, IPR020381=Proteinase inhibitor I25, cystatin, conserved region, IPR018073=Proteinase inhibitor I25, cystatin, conserved site" CG31313 16-Dec-15 2015_12 viable FBgn0263335 CR43416 http://flybase.net/reports/FBgn0263335.html non_protein_coding_gene CR43416 16-Dec-15 2015_12 FBgn0036366 CG10133 http://flybase.net/reports/FBgn0036366.html protein_coding_gene 0004623=phospholipase A2 activity IPR003347=JmjC domain CG10133 16-Dec-15 2015_12 ENSDARG00000035546(jmjd7) ENSXETG00000000049(Q5M8J8_XENTR) viable FBgn0261609 eIF-2ë± eukaryotic translation Initiation Factor 2ë± http://flybase.net/reports/FBgn0261609.html "FBgn0004925, FBgn0024971, FBgn0002589" protein_coding_gene "0000049=tRNA binding, 0003743=translation initiation factor activity, 0005525=GTP binding" "0006413=translational initiation, 0007052=mitotic spindle organization, 0001677=formation of translation initiation ternary complex, 0000022=mitotic spindle elongation" "0005875=microtubule associated complex, 0005850=eukaryotic translation initiation factor 2 complex, 0005851=eukaryotic translation initiation factor 2B complex, 0005829=cytosol" "l(1)19-153, eiF-2alpha, deIF2alpha, eIF-2alpha, eIF-2, eIF-2alphaeIF-2alpha, eIF2alpha, eIF2a, EIF-2alpha, eukaryotic translation initiation factor 2alpha, l(1)14Cf, eIF2-alpha, IF2A_DROME, M(1)19-153, Eif2alpha, Minute (1) 14C, elF2alpha, eukaryotic translation Initiation Factor 2, Eukaryotic initiation factor 2alpha, eIF2 alpha, M(1)8e3-10, eIF-2 alpha, M(1)14C, CG9946, eIF-2 a, eukaryotic translation Initiation Factor 2alpha" "IPR024055=Translation initiation factor 2, alpha subunit, C-terminal, IPR003029=S1 domain, IPR011488=Translation initiation factor 2, alpha subunit, IPR012340=Nucleic acid-binding, OB-fold, IPR024054=Translation initiation factor 2, alpha subunit, middle domain, IPR022967=RNA-binding domain, S1" CG9946 16-Dec-15 2015_12 "ENSDARG00000005827(eif2s1l),ENSDARG00000052178(eif2s1)" YJR007W(SUI2) WBGene00021351(Y37E3.10) ENSXETG00000011221(eif2s1) ENSMUSG00000021116(Eif2s1) ENSG00000134001(EIF2S1) embryonic stage&&larval stage DRSC20327 I -1.948948927 -1.591292857 0.849613111 -0.960623177 0.430935888 0.944776251 FBgn0025676 CkIIë±-i3 CKII-ë± subunit interactor-3 http://flybase.net/reports/FBgn0025676.html protein_coding_gene "CG3217, CkIIalpha-i3, CKIIalpha-i3" CG3217 16-Dec-15 2015_12 "viable,fertile" FBgn0028223 l(3)S007302 lethal (3) S007302 http://flybase.net/reports/FBgn0028223.html gene 0073/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0038396 CG5013 http://flybase.net/reports/FBgn0038396.html protein_coding_gene "IPR019410=Lysine methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG5013 16-Dec-15 2015_12 "ENSDARG00000016343(zgc:92518),ENSDARG00000012051(zgc:110528)" ENSXETG00000019499(C17orf95) ENSMUSG00000020815(1110005A03Rik) ENSG00000181038(METTL23) viable FBgn0032879 CG9317 http://flybase.net/reports/FBgn0032879.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane 38E.10 "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG9317 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" WBGene00003842(oct-1) viable FBgn0035644 DNApol-ëµ58 DNA polymerase ëµ 58kD subunit http://flybase.net/reports/FBgn0035644.html protein_coding_gene "0003677=DNA binding, 0003887=DNA-directed DNA polymerase activity" "0006261=DNA-dependent DNA replication, 0090068=positive regulation of cell cycle process, 0006974=cellular response to DNA damage stimulus, 0032877=positive regulation of DNA endoreduplication" 0008622=epsilon DNA polymerase complex "DNA polymerase epsilon B subunit, 10489, Pole2, dpolepsilonp58, CG10489, POLE2, DNApol-epsilon" "IPR024639=DNA polymerase epsilon subunit B, N-terminal, IPR007185=DNA polymerase alpha/epsilon, subunit B, IPR016266=DNA polymerase epsilon, subunit B" CG10489 16-Dec-15 2015_12 ENSDARG00000038664 YPR175W(DPB2) WBGene00017237(pole-2) ENSXETG00000009123(Q5BJ62_XENTR) ENSMUSG00000020974(Pole2) ENSG00000100479(POLE2) "lethal - all die during pupal stage,size defective,mitotic cell cycle defective,endomitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "wing disc,ventral thoracic disc,eye disc,embryonic/larval salivary gland,embryonic/larval brain,nucleus,trichogen cell,wing" FBgn0004779 Ccp84Ae Ccp84Ae http://flybase.net/reports/FBgn0004779.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "cc4, DmelCcp84Ae, BG:DS00004.5, Ccp, cuticle cluster 4, unnamed, CG1330" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG1330 16-Dec-15 2015_12 viable FBgn0014251 l(2)60Ad lethal (2) 60Ad http://flybase.net/reports/FBgn0014251.html gene 16-Dec-15 2015_12 lethal FBgn0085640 CG41392 http://flybase.net/reports/FBgn0085640.html FBan0041392 protein_coding_gene 16-Dec-15 2015_12 FBgn0010558 l(2)03845 lethal (2) 03845 http://flybase.net/reports/FBgn0010558.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001827 l(1)TS45 lethal (1) TS45 http://flybase.net/reports/FBgn0001827.html gene "l(1)TS-45, lethal (1) no. 45 of T. Shiomi" 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0036723 CG12229 http://flybase.net/reports/FBgn0036723.html protein_coding_gene "0000287=magnesium ion binding, 0030955=potassium ion binding, 0004743=pyruvate kinase activity" "0006096=glycolytic process, 0042866=pyruvate biosynthetic process" 0005829=cytosol pyruvate kinase "IPR015795=Pyruvate kinase, C-terminal, IPR001697=Pyruvate kinase, IPR015794=Pyruvate kinase, alpha/beta" CG12229 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0000774 fs(1)A1242 female sterile (1) A1242 http://flybase.net/reports/FBgn0000774.html gene fs(1)1242 16-Dec-15 2015_12 "female sterile germline-dependent,lethal,non-rescuable maternal effect,recessive,mitotic cell cycle defective" embryo FBgn0083031 snoRNA:ë¬18S-525h snoRNA:ë¬18S-525h http://flybase.net/reports/FBgn0083031.html snoRNA_gene "CR34582, psi18S-525h" CR34582 16-Dec-15 2015_12 FBgn0053792 CG33792 http://flybase.net/reports/FBgn0053792.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33792 16-Dec-15 2015_12 FBgn0000352 cos costa http://flybase.net/reports/FBgn0000352.html "FBgn0014275, FBgn0021829" protein_coding_gene "0042803=protein homodimerization activity, 0005515=protein binding, 0005524=ATP binding, 0005119=smoothened binding, 0008134=transcription factor binding, 0003777=microtubule motor activity, 0003774=motor activity, 0008017=microtubule binding, 0019901=protein kinase binding" "0042981=regulation of apoptotic process, 0043433=negative regulation of sequence-specific DNA binding transcription factor activity, 0045879=negative regulation of smoothened signaling pathway, 0007228=positive regulation of hh target transcription factor activity, 0007476=imaginal disc-derived wing morphogenesis, 0045880=positive regulation of smoothened signaling pathway, 0030707=ovarian follicle cell development, 0007018=microtubule-based movement, 0030162=regulation of proteolysis, 0031647=regulation of protein stability, 0007224=smoothened signaling pathway, 0042992=negative regulation of transcription factor import into nucleus, 0042073=intraciliary transport, 0042994=cytoplasmic sequestering of transcription factor" "0005871=kinesin complex, 0005875=microtubule associated complex, 0005886=plasma membrane, 0012506=vesicle membrane, 0035301=Hedgehog signaling complex, 0005737=cytoplasm" "Kif7, DmCostal2, cos-2, Costal 2, Costal-2, cos2, Enhancer of Epaulette, costal2, l(2)161/28, KIF26A/B, Cos, l(2)cos[[2]], DmCos2, l(2)k16101, Costa, Costal2, costal-2, Cos[2], Cos-2, COS2, Cos2, COS[2], costal 2, COSTAL2, l(2)k16128, CG1708" "IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG1708 16-Dec-15 2015_12 embryonic stage && larval stage " embryonic stage | stage 9-12 , embryonic stage , embryonic stage | early , larval stage " "

segment polarity , segment | anterior

, dorsal mesothoracic disc | anterior

" "lethal,hyperplasia,recessive,visible,dominant,cell non-autonomous,somatic clone,wild-type,rescuable maternal effect,germline clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,partially,viable" "imaginal disc,wing,female gonopod,dorsal,ventral,genital arch,vulva,epiproct,hypoproct,lateral plate,clasper,hypandrial process,posterior compartment,anterior compartment,eye,cell non-autonomous,somatic clone,adult head,antenna,eye disc,wing disc,embryonic epidermis,germline clone,denticle belt,embryonic/first instar larval cuticle,embryonic segment,wing vein L3,ectopic,polar follicle cell,wing vein,follicle cell,oocyte,sex comb,pupal epidermis,maternal effect,embryonic abdominal segment,border follicle cell,supernumerary,haltere,proximal,wing vein L4,1st posterior cell,anterior,wing blade,egg chamber,germarium,interfollicle cell" FBgn0086757 cbs centrosomin's beautiful sister http://flybase.net/reports/FBgn0086757.html "FBgn0026256, FBgn0033840" protein_coding_gene "0042803=protein homodimerization activity, 0030306=ADP-ribosylation factor binding, 0017137=Rab GTPase binding" "0007098=centrosome cycle, 0000042=protein targeting to Golgi, 0048193=Golgi vesicle transport" "0000785=chromatin, 0005794=Golgi apparatus, 0005819=spindle, 0000138=Golgi trans cisterna, 0005737=cytoplasm, 0005813=centrosome, 0048471=perinuclear region of cytoplasm" "Golgin 97, dem, dementin, dGolgin-97, CG4840, Centrosomin's beautiful sister, Cbs" IPR000237=GRIP CG4840 16-Dec-15 2015_12 ENSDARG00000008979(golga1) ENSMUSG00000026754(Golga1) ENSG00000136935(GOLGA1) "lethal - all die before end of embryonic stage,partially,some die during embryonic stage,viable" "centrosomenos.UTR.THsimVP16,syncytial blastoderm embryo,stage 5 embryo,centrosome | embryonic stage 4nos.UTR.THsimVP16,nucleus | embryonic stage 4nos.UTR.THsimVP16,spindle | embryonic stage 4nos.UTR.THsimVP16,centrosome | embryonic stage 5nos.UTR.THsimVP16,nucleus | embryonic stage 5nos.UTR.THsimVP16,centrosome | supernumerarynos.UTR.THsimVP16" FBgn0266522 Sxl::Soce\Soce-Sxl http://flybase.net/reports/FBgn0266522.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,male limited,partially lethal - majority die,viable" FBgn0085716 CG41596 http://flybase.net/reports/FBgn0085716.html FBan0041596 protein_coding_gene 16-Dec-15 2015_12 FBgn0065662 l(2)SH0710 lethal (2) SH0710 http://flybase.net/reports/FBgn0065662.html gene l(2)SH2 0710 16-Dec-15 2015_12 "lethal,recessive" FBgn0260504 Pkc98E::Pkn http://flybase.net/reports/FBgn0260504.html engineered_fusion_gene Pkn-PKC98E 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0265966 CR44753 http://flybase.net/reports/FBgn0265966.html non_protein_coding_gene CR44753 16-Dec-15 2015_12 FBgn0033581 CG12391 http://flybase.net/reports/FBgn0033581.html FBgn0044672 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0008270=zinc ion binding" "0006351=transcription, DNA-templated" 0005634=nucleus anon-WO0140519.201 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR027775=C2H2- zinc finger protein family" CG12391 16-Dec-15 2015_12 "viable,fertile" FBgn0024553 l(3)L4092 lethal (3) L4092 http://flybase.net/reports/FBgn0024553.html gene 16-Dec-15 2015_12 "lethal,recessive" "germline cell,male" FBgn0003729 tny thorny http://flybase.net/reports/FBgn0003729.html gene 16-Dec-15 2015_12 "male sterile,visible,viable,poor,eye color defective" "eye,adult thorax & macrochaeta,adult head & macrochaeta,wing,pigment cell" FBgn0002109 l(2)1076 lethal (2) 1076 http://flybase.net/reports/FBgn0002109.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069135 mcl(3)Z6257 mcl(3)Z6257 http://flybase.net/reports/FBgn0069135.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0263392 Tet Ten-Eleven Translocation (TET) family protein http://flybase.net/reports/FBgn0263392.html "FBgn0035376, FBgn0035378" protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" "CG2083, TET Family Protein, Idax, CG9973, CG43444, dTet" "IPR002857=Zinc finger, CXXC-type, IPR024779=2OGFeDO domain, nucleic acid-modifying type" CG43444 16-Dec-15 2015_12 ENSDARG00000062646(LOC794865) ENSMUSG00000040943(Tet2) "ENSG00000138336(TET1),ENSG00000187605(TET3)" DRSC08550 I -0.378185995 -1.874072846 -0.318890946 0.232404867 -1.227318041 -0.003990655 FBgn0000274 Pka-C2 "Protein kinase, cAMP-dependent, catalytic subunit 2" http://flybase.net/reports/FBgn0000274.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004691=cAMP-dependent protein kinase activity" "0022008=neurogenesis, 0006468=protein phosphorylation" 0005952=cAMP-dependent protein kinase complex "PKA C2, DC1a, CG12066, CdkB, cAMP-dependent protein kinase 2, DC1, cAMP-dependent protein kinase type II, PKA" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG12066 16-Dec-15 2015_12 embryonic stage&&pupal stage&&adult stage "viable,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032869 CG17470 http://flybase.net/reports/FBgn0032869.html "FBgn0044560, FBgn0045901" protein_coding_gene 0007498=mesoderm development "anon-WO0140519.68, 38D.25, anon-WO0153538.51" CG17470 16-Dec-15 2015_12 FBgn0052378 CG32378 http://flybase.net/reports/FBgn0052378.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032229 CG5045 http://flybase.net/reports/FBgn0032229.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005739=mitochondrion "IPR023562=Clp protease proteolytic subunit /Translocation-enhancing protein TepA, IPR029045=ClpP/crotonase-like domain, IPR018215=ClpP, active site, IPR001907=ATP-dependent Clp protease proteolytic subunit" CG5045 16-Dec-15 2015_12 ENSDARG00000020679(clpp) WBGene00014172(clpp-1) ENSXETG00000005576(CLPP) ENSMUSG00000002660(Clpp) ENSG00000125656(CLPP) viable FBgn0065059 snoRNA:660 snoRNA:660 http://flybase.net/reports/FBgn0065059.html FBgn0053780 snoRNA_gene 0005730=nucleolus "Dm-660, chr2R:16453519..16453648, CR33780" CR33780 16-Dec-15 2015_12 FBgn0053391 5SrRNA:CR33391 5SrRNA:CR33391 http://flybase.net/reports/FBgn0053391.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33391 CR33391 16-Dec-15 2015_12 FBgn0261881 l(2)35Be lethal (2) 35Be http://flybase.net/reports/FBgn0261881.html "FBgn0001975, FBgn0028535, FBgn0027870" protein_coding_gene 0005829=cytosol "br10, C3, BG:DS00929.2, CG4140, l(2)br10, lethal group C3, lethal 10 in the black-reduced region" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG4140 16-Dec-15 2015_12 ENSDARG00000023508(ankrd49) WBGene00017831(F26F4.12) ENSXETG00000006415(ANKRD49) ENSMUSG00000031931(Ankrd49) ENSG00000168876(ANKRD49) FBgn0050363 cola comas sola http://flybase.net/reports/FBgn0050363.html FBgn0033284 protein_coding_gene "cola, comas sola, CG30363, CG2149" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30363 16-Dec-15 2015_12 FBgn0032895 twit target of wit http://flybase.net/reports/FBgn0032895.html FBgn0063141 protein_coding_gene 0046928=regulation of neurotransmitter secretion 0046658=anchored component of plasma membrane "BcDNA:LD40063, CG9335" CG9335 16-Dec-15 2015_12 "viable,fertile,neurophysiology defective" embryonic/larval neuromuscular junction FBgn0260037 33W1 http://flybase.net/reports/FBgn0260037.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0038646 CG7715 http://flybase.net/reports/FBgn0038646.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG7715 16-Dec-15 2015_12 viable FBgn0032487 Ski6 Ski6 http://flybase.net/reports/FBgn0032487.html protein_coding_gene 0000175=3'-5'-exoribonuclease activity 0010468=regulation of gene expression "0000176=nuclear exosome (RNase complex), 0000177=cytoplasmic exosome (RNase complex), 0005737=cytoplasm, 0005652=nuclear lamina, 0035327=transcriptionally active chromatin" "Rrp41, dSki6, CG15481, dRrp41" "IPR001247=Exoribonuclease, phosphorolytic domain 1, IPR027408=PNPase/RNase PH domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR015847=Exoribonuclease, phosphorolytic domain 2" CG15481 16-Dec-15 2015_12 ENSDARG00000036060(exosc6) YGR195W(SKI6) WBGene00007201(exos-4.1) ENSXETG00000004668(exosc4) ENSMUSG00000034259(Exosc4) ENSG00000178896(EXOSC4) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0034602 Lapsyn Leucine-rich repeat activity-regulated protein at synapses http://flybase.net/reports/FBgn0034602.html protein_coding_gene 0007399=nervous system development "0043025=neuronal cell body, 0042734=presynaptic membrane" "CT35842, CG15658" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG15658 16-Dec-15 2015_12 "neuroanatomy defective,learning defective,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,recessive,wild-type,viable" "varicosity | supernumerary | third instar larval stage,neuromuscular junction | third instar larval stage,varicosity | third instar larval stagehow-24B,neuromuscular junction | third instar larval stagehow-24B,NMJ bouton,supernumerary,synapse | third instar larval stage" FBgn0260348 GSd484 http://flybase.net/reports/FBgn0260348.html gene 16-Dec-15 2015_12 lethal FBgn0036805 Chmp1 Charged multivesicular body protein 1 http://flybase.net/reports/FBgn0036805.html protein_coding_gene "0007034=vacuolar transport, 0032509=endosome transport via multivesicular body sorting pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway" "0000815=ESCRT III complex, 0045177=apical part of cell, 0005770=late endosome" "CG4108, VPS46, Chmp1, CHMP1" IPR005024=Snf7 family CG4108 16-Dec-15 2015_12 ENSDARG00000035548(chmp1b) YKR035W-A(DID2) WBGene00017735(F23C8.6) ENSXETG00000022122(chmp1b) ENSMUSG00000031242(2610002M06Rik) ENSG00000215104 FBgn0011283 Obp28a Odorant-binding protein 28a http://flybase.net/reports/FBgn0011283.html protein_coding_gene "0005549=odorant binding, 0005550=pheromone binding, 0008145=phenylalkylamine binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "Pbprp5, Pheromone-binding protein-related protein 5, obp28a, PBPRP-5, PB-PRP5, 28a, CG6641, pbprp-5, Obp28a, PBP5, PBPRP5, pbprp5, DmelObp28a" IPR006170=Pheromone/general odorant binding protein CG6641 16-Dec-15 2015_12 adult stage " antennal segment 3 | medial

, sensillum basiconicum of antennal segment 3

, antennal segment 3 | posterior

" "partially lethal - majority die,some die during pupal stage" DRSC03394 IK 2.061624687 -0.983373749 0.309128604 -0.230023421 -2.098044453 0.427165028 FBgn0040617 CG12515 http://flybase.net/reports/FBgn0040617.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266874 CR45335 http://flybase.net/reports/FBgn0266874.html non_protein_coding_gene CR45335 16-Dec-15 2015_12 FBgn0067642 tortuous-trachea-1 tortuous trachea 1 http://flybase.net/reports/FBgn0067642.html gene "0007155=cell adhesion, 0007426=tracheal outgrowth, open tracheal system" 16-Dec-15 2015_12 FBgn0058119 CG40119 http://flybase.net/reports/FBgn0058119.html FBan0040119 protein_coding_gene 16-Dec-15 2015_12 FBgn0050185 CG30185 http://flybase.net/reports/FBgn0050185.html "FBgn0027712, FBgn0034875" protein_coding_gene "0016876=ligase activity, forming aminoacyl-tRNA and related compounds, 0005524=ATP binding" 0043039=tRNA aminoacylation "0005875=microtubule associated complex, 0005737=cytoplasm" "CG5365, anon-EST:Posey25" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal, IPR000924=Glutamyl/glutaminyl-tRNA synthetase" CG30185 16-Dec-15 2015_12 ENSDARG00000071774(wu:fe14c11) ENSXETG00000020459(EEF1E1) ENSMUSG00000001707(Eef1e1) ENSG00000124802(EEF1E1) "viable,fertile" FBgn0041086 zep zeppelin http://flybase.net/reports/FBgn0041086.html gene 0008362=chitin-based embryonic cuticle biosynthetic process 16-Dec-15 2015_12 embryonic/first instar larval cuticle FBgn0261924 CR42791 http://flybase.net/reports/FBgn0261924.html non_protein_coding_gene "lincRNA.159, CG42791" CR42791 16-Dec-15 2015_12 FBgn0023219 E(lz)178 E(lz)178 http://flybase.net/reports/FBgn0023219.html gene 16-Dec-15 2015_12 wild-type FBgn0037817 Cyp12e1 Cyp12e1 http://flybase.net/reports/FBgn0037817.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process 0005739=mitochondrion "12e1, CG14680" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG14680 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" viable FBgn0033133 Tsp42Ek Tetraspanin 42Ek http://flybase.net/reports/FBgn0033133.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp42Ek, tetraspanin 42E, CG12841" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG12841 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0027995 l(3)S125801b lethal (3) S125801b http://flybase.net/reports/FBgn0027995.html gene "l(3)S125801, 1258/01" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0082354 HM30 HM30 http://flybase.net/reports/FBgn0082354.html gene 16-Dec-15 2015_12 FBgn0045044 fs(1)56 female sterile (1) 56 http://flybase.net/reports/FBgn0045044.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "egg,dorsal appendage,ovary" FBgn0065572 l(2)SH0959 lethal (2) SH0959 http://flybase.net/reports/FBgn0065572.html gene l(2)SH2 0959 16-Dec-15 2015_12 "lethal,recessive" FBgn0001022 fs(3)A13 female sterile (3) A13 http://flybase.net/reports/FBgn0001022.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" female reproductive system FBgn0034958 CG3907 http://flybase.net/reports/FBgn0034958.html protein_coding_gene 0007076=mitotic chromosome condensation 0000796=condensin complex IPR027120=Structural maintenance of chromosomes Smc2 CG3907 16-Dec-15 2015_12 ENSXETG00000016352(KIAA0494) ENSMUSG00000034210(4732418C07Rik) viable FBgn0264500 CR43899 http://flybase.net/reports/FBgn0264500.html non_protein_coding_gene CR43899 16-Dec-15 2015_12 FBgn0082689 E(ftz)1427 E(ftz)1427 http://flybase.net/reports/FBgn0082689.html gene 1427 16-Dec-15 2015_12 FBgn0267643 CR45981 http://flybase.net/reports/FBgn0267643.html non_protein_coding_gene CR45981 16-Dec-15 2015_12 FBgn0065872 l(2)SH0255 lethal (2) SH0255 http://flybase.net/reports/FBgn0065872.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038100 Paip2 polyA-binding protein interacting protein 2 http://flybase.net/reports/FBgn0038100.html protein_coding_gene 0005515=protein binding "0017148=negative regulation of translation, 0001558=regulation of cell growth" "PolyA-binding protein interacting protein 2, dPaip2, paip2, CG12358" "IPR009818=Ataxin-2, C-terminal" CG12358 16-Dec-15 2015_12 ENSDARG00000008706(zgc:73265) ENSXETG00000025676(paip2) "ENSMUSG00000045896(Paip2b),ENSMUSG00000037058(Paip2)" "ENSG00000124374(PAIP2B),ENSG00000120727(PAIP2)" "visible,cell growth defective,cell size defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing disc,ommatidium,embryonic/larval fat body" FBgn0060539 l(3)S100305 lethal (3) S100305 http://flybase.net/reports/FBgn0060539.html gene 1003/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0031435 Elba2 Early boundary activity 2 http://flybase.net/reports/FBgn0031435.html protein_coding_gene "0043035=chromatin insulator sequence binding, 0043565=sequence-specific DNA binding" 0031937=positive regulation of chromatin silencing "0005634=nucleus, 0005677=chromatin silencing complex" "CG9883, Elba, early boundary factor" IPR018379=BEN domain CG9883 16-Dec-15 2015_12 viable FBgn0267039 CR45483 http://flybase.net/reports/FBgn0267039.html non_protein_coding_gene CR45483 16-Dec-15 2015_12 FBgn0065506 l(2)SH1190 lethal (2) SH1190 http://flybase.net/reports/FBgn0065506.html gene l(2)SH2 1190 16-Dec-15 2015_12 "lethal,recessive" FBgn0005484 l(1)ts1415 lethal (1) ts1415 http://flybase.net/reports/FBgn0005484.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0266815 CR45277 http://flybase.net/reports/FBgn0266815.html non_protein_coding_gene CR45277 16-Dec-15 2015_12 FBgn0028938 CG16886 http://flybase.net/reports/FBgn0028938.html protein_coding_gene "BG:DS00180.2, vajk-1" CG16886 16-Dec-15 2015_12 ENSXETG00000000145() "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0058267 CG40267 http://flybase.net/reports/FBgn0058267.html FBan0040267 protein_coding_gene 16-Dec-15 2015_12 FBgn0065301 l(2)SH1986 lethal (2) SH1986 http://flybase.net/reports/FBgn0065301.html gene l(2)SH2 1986 16-Dec-15 2015_12 "lethal,recessive" FBgn0084029 CG41468 http://flybase.net/reports/FBgn0084029.html FBan0041468 protein_coding_gene 16-Dec-15 2015_12 FBgn0032231 CG5056 http://flybase.net/reports/FBgn0032231.html protein_coding_gene CG5056 16-Dec-15 2015_12 FBgn0038645 CG7714 http://flybase.net/reports/FBgn0038645.html FBgn0026298 protein_coding_gene 0008061=chitin binding "0006030=chitin metabolic process, 0046331=lateral inhibition" 0005576=extracellular region anon-EST:ParkEST066 IPR002557=Chitin binding domain CG7714 16-Dec-15 2015_12 "viable,visible" "chaeta,mesothoracic tergum" FBgn0065807 l(2)SH0390 lethal (2) SH0390 http://flybase.net/reports/FBgn0065807.html gene l(2)SH2 0390 16-Dec-15 2015_12 "lethal,recessive" FBgn0038734 CG11453 http://flybase.net/reports/FBgn0038734.html protein_coding_gene 0016207=4-coumarate-CoA ligase activity 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG11453 16-Dec-15 2015_12 viable FBgn0031710 Vps52 Vacuolar protein sorting 52 http://flybase.net/reports/FBgn0031710.html protein_coding_gene 0005515=protein binding 0032456=endocytic recycling "0005802=trans-Golgi network, 0005794=Golgi apparatus" CG7371 IPR007258=Vps52 CG7371 16-Dec-15 2015_12 ENSDARG00000009175(vps52) YDR484W(VPS52) WBGene00007059(vps-52) ENSXETG00000020385(VPS52) ENSMUSG00000024319(Vps52) "ENSG00000206214,ENSG00000206286,ENSG00000112478" "viable,visible,planar polarity defective" trichogen cell FBgn0035019 Ir60e Ionotropic receptor 60e http://flybase.net/reports/FBgn0035019.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "IR60e, ionotropic receptor 60e, DmelIR60e, CG13592" CG13592 16-Dec-15 2015_12 viable FBgn0065212 l(2)SH2259 lethal (2) SH2259 http://flybase.net/reports/FBgn0065212.html gene l(2)SH2 2259 16-Dec-15 2015_12 "lethal,recessive" FBgn0033814 CG4670 http://flybase.net/reports/FBgn0033814.html protein_coding_gene 0016971=flavin-linked sulfhydryl oxidase activity "0055114=oxidation-reduction process, 0045454=cell redox homeostasis" "QSOX1, DmQSOX1, lincRNA.300" "IPR017937=Thioredoxin, conserved site, IPR017905=ERV/ALR sulfhydryl oxidase domain, IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG4670 16-Dec-15 2015_12 ENSDARG00000039459(si:dkey-39n1.2) WBGene00018533(F47B7.2) "ENSXETG00000023156(qscn6),ENSXETG00000000729(QSOX2)" "ENSMUSG00000033684(Qsox1),ENSMUSG00000036327(Qsox2)" "ENSG00000165661(QSOX2),ENSG00000116260(QSOX1)" viable DRSC06878 K 0.275797445 0.668863621 -0.380386302 0.129656758 0.270278027 -2.036244264 FBgn0039620 wat waterproof http://flybase.net/reports/FBgn0039620.html protein_coding_gene "0050062=long-chain-fatty-acyl-CoA reductase activity, 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity" "0035002=liquid clearance, open tracheal system, 0035149=lumen formation, open tracheal system" "0045177=apical part of cell, 0005737=cytoplasm" "Wat, CG1443" "IPR016040=NAD(P)-binding domain, IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding" CG1443 16-Dec-15 2015_12 "viable,lethal,recessive,fertile" "tracheal branch primordium | embryonic stage 17,tracheal branch primordium,tracheal lumen,taenidium" FBgn0031060 CG14231 http://flybase.net/reports/FBgn0031060.html protein_coding_gene 0004222=metalloendopeptidase activity "IPR000905=Gcp-like domain, IPR017861=Kae1/TsaD family, IPR022450=tRNA N6-adenosine threonylcarbamoyltransferase, TsaD" CG14231 16-Dec-15 2015_12 ENSDARG00000000651(osgepl1) YDL104C(QRI7) WBGene00007237(C01G10.10) ENSXETG00000009883(OSGEPL1) ENSMUSG00000026096(Osgepl1) ENSG00000128694(OSGEPL1) FBgn0036745 CG7484 http://flybase.net/reports/FBgn0036745.html FBgn0062874 protein_coding_gene 0015036=disulfide oxidoreductase activity 0045454=cell redox homeostasis "0005783=endoplasmic reticulum, 0005634=nucleus, 0012505=endomembrane system" "Sep15, Prise 8, BcDNA:SD16138" "IPR012336=Thioredoxin-like fold, IPR014912=Sep15/SelM redox" CG7484 16-Dec-15 2015_12 WBGene00022297(Y76B12C.3) ENSMUSG00000037072(Sep15) ENSG00000183291(SEP15) viable FBgn0039977 CG17454 http://flybase.net/reports/FBgn0039977.html protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome" "0005634=nucleus, 0005737=cytoplasm, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome" SPF30 "IPR010304=Survival motor neuron, IPR002999=Tudor domain" CG17454 16-Dec-15 2015_12 ENSDARG00000056235(smndc1) WBGene00004891(smr-1) ENSXETG00000015415(smndc1) ENSMUSG00000025024(Smndc1) ENSG00000119953(SMNDC1) FBgn0033697 Cyp6t3 Cyp6t3 http://flybase.net/reports/FBgn0033697.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0006697=ecdysone biosynthetic process, 0048638=regulation of developmental growth" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG8457, Cyp6T3, 6t3" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG8457 16-Dec-15 2015_12 YHR007C(ERG11) "large body,developmental rate defective,visible,viable,feeding behavior defective" "pupa,mouth hooks" FBgn0053731 snmRNA:430:CR33731 snmRNA:430:CR33731 http://flybase.net/reports/FBgn0053731.html non_protein_coding_gene CR33731 CR33731 16-Dec-15 2015_12 FBgn0015470 l(2)44Fe lethal (2) 44Fe http://flybase.net/reports/FBgn0015470.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0030356 CR32661 http://flybase.net/reports/FBgn0030356.html non_protein_coding_gene "bs26d09.y1, bs07b04.y1, bs05a04.y1, CG18184" CR32661 16-Dec-15 2015_12 FBgn0259261 EP-Z http://flybase.net/reports/FBgn0259261.html gene 16-Dec-15 2015_12 visible wing vein FBgn0060650 l(3)S083502b lethal (3) S083502b http://flybase.net/reports/FBgn0060650.html gene 0835/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0250876 Sema-5c Semaphorin-5c http://flybase.net/reports/FBgn0250876.html "FBgn0028679, FBgn0025685, FBgn0036245, FBgn0086382" protein_coding_gene "0001700=embryonic development via the syncytial blastoderm, 0048036=central complex development, 0007411=axon guidance, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 0042048=olfactory behavior, 0048854=brain morphogenesis" 0005886=plasma membrane "Sema-5c, semiphorin, Sema 5c, Semaphorin, sema-5c, CT17880, Sema-5C, semaphorin 5C, CK02567, BG01245, Semaphorin 5C, semaphorin, CG5661, sema 5c, BEST:CK02567" "IPR001627=Sema domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR002165=Plexin repeat, IPR027231=Semaphorin, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR016201=Plexin-like fold" CG5661 16-Dec-15 2015_12 "ENSDARG00000058821(sema5a),ENSDARG00000061471(sema5b)" "ENSMUSG00000022231(Sema5a),ENSMUSG00000052133(Sema5b)" "ENSG00000112902(SEMA5A),ENSG00000082684(SEMA5B)" " adult stage && oogenesis stage | stage S10 , embryonic stage | late , embryonic stage | blastoderm , embryonic stage && pupal stage , embryonic stage | stage 12 , embryonic stage , embryonic stage | stage 2 " " oocyte

, embryonic/larval dorsal vessel

, ectoderm | restricted

, nurse cell

, amnioserosa

, muscle attachment site

, visceral mesoderm &&of anterior embryonic/larval midgut

,

ubiquitous , embryonic/larval pericardial cell

" FBgn0005527 l(2)52ACd lethal (2) 52ACd http://flybase.net/reports/FBgn0005527.html gene unnamed 16-Dec-15 2015_12 FBgn0022101 l(2)k07127 lethal (2) k07127 http://flybase.net/reports/FBgn0022101.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052137 CG32137 http://flybase.net/reports/FBgn0052137.html "FBgn0036387, FBgn0036388" protein_coding_gene 0048812=neuron projection morphogenesis "CG17366, CG17365" CG32137 16-Dec-15 2015_12 "ENSXETG00000012189(CCDC64),ENSXETG00000011371(Q6DIX6_XENTR)" ENSMUSG00000041609(Ccdc64) ENSG00000135127(CCDC64) "viable,fertile" FBgn0019801 l(1)04 lethal (1) 04 http://flybase.net/reports/FBgn0019801.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031935 CG13793 http://flybase.net/reports/FBgn0031935.html protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity" 0006836=neurotransmitter transport 0016021=integral component of membrane IPR000175=Sodium:neurotransmitter symporter CG13793 16-Dec-15 2015_12 "viable,fertile" FBgn0259350 C27 http://flybase.net/reports/FBgn0259350.html gene 16-Dec-15 2015_12 visible wing FBgn0034846 CG9863 http://flybase.net/reports/FBgn0034846.html FBgn0063707 protein_coding_gene BcDNA:AT26616 CG9863 16-Dec-15 2015_12 viable FBgn0066347 l(3)99DEh lethal (3) 99DEh http://flybase.net/reports/FBgn0066347.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065265 l(2)SH2069 lethal (2) SH2069 http://flybase.net/reports/FBgn0065265.html gene l(2)SH2 2069 16-Dec-15 2015_12 "lethal,recessive" FBgn0267527 CR45867 http://flybase.net/reports/FBgn0267527.html non_protein_coding_gene CR45867 16-Dec-15 2015_12 FBgn0044019 S-element\T T http://flybase.net/reports/FBgn0044019.html transposable_element_gene "0004803=transposase activity, 0003677=DNA binding" "0015074=DNA integration, 0006313=transposition, DNA-mediated" "IPR002492=Transposase, Tc1-like, IPR009057=Homeodomain-like" 16-Dec-15 2015_12 FBgn0267068 CR45512 http://flybase.net/reports/FBgn0267068.html non_protein_coding_gene CR45512 16-Dec-15 2015_12 FBgn0040020 MED21 Mediator complex subunit 21 http://flybase.net/reports/FBgn0040020.html "FBgn0058364, FBan0017397" protein_coding_gene "0003713=transcription coactivator activity, 0001104=RNA polymerase II transcription cofactor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0016591=DNA-directed RNA polymerase II, holoenzyme, 0005634=nucleus, 0016592=mediator complex" "CG40364, dTRAP19, Med21, CG17397, dSRB7, Trap19, Mediator, p18" "IPR021384=Mediator complex, subunit Med21" CG17397 16-Dec-15 2015_12 ENSDARG00000026839(med21) YDR308C(SRB7) WBGene00007704(mdt-21) ENSMUSG00000030291(Med21) ENSG00000152944(MED21) "viable,visible" mesothoracic tergum FBgn0060714 l(3)S070005a lethal (3) S070005a http://flybase.net/reports/FBgn0060714.html gene 0700/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040844 CG12572 http://flybase.net/reports/FBgn0040844.html protein_coding_gene 16-Dec-15 2015_12 FBgn0050503 CG30503 http://flybase.net/reports/FBgn0050503.html "FBgn0033171, FBgn0062430" protein_coding_gene "0005509=calcium ion binding, 0004623=phospholipase A2 activity" "0016042=lipid catabolic process, 0006644=phospholipid metabolic process" "BcDNA:RH50933, CG1672" "IPR016090=Phospholipase A2 domain, IPR013090=Phospholipase A2, active site, IPR001211=Phospholipase A2" CG30503 16-Dec-15 2015_12 ENSDARG00000069823(LOC100149324) "ENSXETG00000019260(PROCA1),ENSXETG00000016153(PLA2G3)" viable FBgn0083233 EP712 EP712 http://flybase.net/reports/FBgn0083233.html gene 16-Dec-15 2015_12 FBgn0015559 unch unchained http://flybase.net/reports/FBgn0015559.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "chordotonal organ,lateral" FBgn0263772 CG43689 http://flybase.net/reports/FBgn0263772.html "FBgn0052778, FBgn0029691, FBgn0052790, FBgn0262973, FBgn0029692" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG32778, CG32790, CG43284, CG4985, CG15376" "IPR002515=Zinc finger, C2HC-type" CG43689 16-Dec-15 2015_12 DRSC18046 E -0.262569822 -0.884354941 -0.308781299 -2.010695163 -1.456967828 -0.922442052 FBgn0262141 CG42867 http://flybase.net/reports/FBgn0262141.html protein_coding_gene CG42867 16-Dec-15 2015_12 FBgn0267969 CR46247 http://flybase.net/reports/FBgn0267969.html non_protein_coding_gene lincRNA.944 CR46247 16-Dec-15 2015_12 FBgn0037139 CG14563 http://flybase.net/reports/FBgn0037139.html protein_coding_gene CG14563 16-Dec-15 2015_12 FBgn0013483 l(1)3PP4 lethal (1) 3PP4 http://flybase.net/reports/FBgn0013483.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic epidermis,germline clone,ventral" FBgn0002470 l(3)SG25 lethal (3) SG25 http://flybase.net/reports/FBgn0002470.html FBgn0004721 gene "l(3)A3, l(3)g30L, l(3)dsl3, l(3)dsl-3" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0086365 Orct2 Organic cation transporter 2 http://flybase.net/reports/FBgn0086365.html "FBgn0029146, FBgn0062704, FBgn0039176" protein_coding_gene "0008324=cation transmembrane transporter activity, 0015101=organic cation transmembrane transporter activity" "0030307=positive regulation of cell growth, 0015695=organic cation transport, 0007390=germ-band shortening, 0040018=positive regulation of multicellular organism growth, 0055085=transmembrane transport" 0016021=integral component of membrane "CG13610, Organic cation transporter 2, calderon, EP1072, orct2, cald, EP(3)1072" "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG13610 16-Dec-15 2015_12 "ENSDARG00000071049(si:dkey-119m7.4),ENSDARG00000054690(LOC100001249),ENSDARG00000059166(zgc:153639)" "YML123C(PHO84),YCR098C(GIT1)" "ENSXETG00000016581(),ENSXETG00000016584(slc22a5)" "ENSMUSG00000063652(Slc22a21),ENSMUSG00000018900(Slc22a5),ENSMUSG00000020334(Slc22a4)" ENSG00000172940(SLC22A13) "viable,cell lethalcell lethal,somatic clone,decreased cell size,cell autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage,small body,cold sensitive,developmental rate defective" "germ band,wing margin bristle,somatic clone,chaeta & mesothoracic tergum | somatic clone,wing,eye" FBgn0060441 l(3)S123713 lethal (3) S123713 http://flybase.net/reports/FBgn0060441.html gene 1237/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0001263 inaD inactivation no afterpotential D http://flybase.net/reports/FBgn0001263.html protein_coding_gene "0005515=protein binding, 0030159=receptor signaling complex scaffold activity, 0005198=structural molecule activity, 0031473=myosin III binding, 0005516=calmodulin binding, 0009881=photoreceptor activity, 0017022=myosin binding" "0007602=phototransduction, 0016059=deactivation of rhodopsin mediated signaling, 0007605=sensory perception of sound, 0008104=protein localization, 0050962=detection of light stimulus involved in sensory perception, 0071482=cellular response to light stimulus" "0005886=plasma membrane, 0016027=inaD signaling complex, 0016028=rhabdomere" "Inactivation No Afterpotential D, CG3504, inactivation-no-afterpotential D, inactivation, no after-depolarization, INAD, inactivation-no-afterpotential-D, Ina-D, inactivation no after-potential D, inactivation-no after potential D, Inactivation no afterpotential D, InaD" IPR001478=PDZ domain CG3504 16-Dec-15 2015_12 ENSDARG00000024964(inadl) "ENSG00000072201(LNX1),ENSG00000139517(LNX2)" adult stage adult head

adult stage " ocellus

, photoreceptor cell

, rhabdomere

, retina

" "neurophysiology defective,visual behavior defective,wild-type,recessive,auditory perception defective,phototaxis defective,dominant,viable" "eye photoreceptor cell,photoreceptor,photoreceptor cell,retina" FBgn0000427 1-Dec defective chorion 1 http://flybase.net/reports/FBgn0000427.html FBgn0000645 protein_coding_gene 0005213=structural constituent of chorion "0007306=eggshell chorion assembly, 0007304=chorion-containing eggshell formation" "0005576=extracellular region, 0042600=chorion" "fs(1)1501, 39051, fs(1)12-365, fs(1)12-3907, fs(1)M102, fs(1)384, CG2175, fs(1)A257, fs(1)M1021, dec1, fs(1)11-549, Fc, fs(1)13-453, Fcp7C, fs(1)13C-73, fs(1)14A-114, defective chorion, fs(1)5, fs(1)C1, fs(1)12-4860, fs(1)12-403, Fc1, fs(1)12-1873, fs(1)13C-57, Follicle cell protein 7C, fs(1)14E19, fs(1)A384, dec, fs(1)12-3512, dec[[1]], fs(1)14-963, fs(1)12-2514" "IPR006719=DEC-1 protein, N-terminal, IPR006718=Dec-1 repeat, IPR006720=Dec-1 protein, C-terminal" CG2175 16-Dec-15 2015_12 adult stage && oogenesis stage | stage S10 egg chamber

" adult stage && oogenesis stage | stage S10B , adult stage && oogenesis stage | stage S10A " follicle cell

"female sterile,male fertile,dominant,female fertile,electrophoretic variant,wild-type,fertile,female sterile soma-dependent,recessive,viable" "chorion,dorsal appendage,egg,endochorion,vitelline membrane,chorion | somatic clone" FBgn0262214 mir-929 mir-929 stem loop http://flybase.net/reports/FBgn0262214.html miRNA_gene "dme-mir-929, CR42921, miR-929" CR42921 16-Dec-15 2015_12 "viable,visible" wing vein FBgn0083234 EP704 EP704 http://flybase.net/reports/FBgn0083234.html gene 16-Dec-15 2015_12 FBgn0266476 coconut http://flybase.net/reports/FBgn0266476.html gene 16-Dec-15 2015_12 "partially lethal,female sterile,male sterile" "egg chamber,germline clone,oocyte" FBgn0013504 l(1)PB8P lethal (1) PB8P http://flybase.net/reports/FBgn0013504.html gene 16-Dec-15 2015_12 "lethal,germline clone,recessive,rescuable maternal effect" "embryo,germline clone,embryonic head" FBgn0037538 CG3223 http://flybase.net/reports/FBgn0037538.html protein_coding_gene "IPR029071=Ubiquitin-related domain, IPR009060=UBA-like, IPR015940=Ubiquitin-associated domain" CG3223 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0051871 CG31871 http://flybase.net/reports/FBgn0051871.html "FBgn0032277, FBgn0032278" protein_coding_gene 0004806=triglyceride lipase activity 0048812=neuron projection morphogenesis "CG17099, CG17087" "IPR000073=Alpha/beta hydrolase fold-1, IPR029058=Alpha/Beta hydrolase fold" CG31871 16-Dec-15 2015_12 ENSDARG00000018529(lipf) YKL140W(TGL1) "WBGene00021963(Y57E12B.3),WBGene00010062(F54F3.3),WBGene00020016(R11G11.14),WBGene00022642(ZK6.7),WBGene00009773(F46B6.8)" ENSXETG00000009273(lipA) "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" "viable,fertile" DRSC02571 K 0.152164934 0.605440329 -1.06891502 -0.424724861 0.198315477 1.586103966 FBgn0034380 Vps51 Vacuolar protein sorting 51 http://flybase.net/reports/FBgn0034380.html protein_coding_gene CG15087 IPR016159=Cullin repeat-like-containing domain CG15087 16-Dec-15 2015_12 ENSDARG00000062016(c11orf2) WBGene00015176(vps-51) ENSXETG00000001637(Q4V9Y0_XENTR) ENSMUSG00000024797(1110014N23Rik) ENSG00000149823(C11orf2) viable FBgn0020854 fs(2)al female sterile (2) al http://flybase.net/reports/FBgn0020854.html gene fs(2L)al 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "embryo,maternal effect,egg,chorion | maternal effect" FBgn0250847 CG14034 http://flybase.net/reports/FBgn0250847.html "FBgn0031691, FBgn0066876" protein_coding_gene "0004620=phospholipase activity, 0052689=carboxylic ester hydrolase activity" "0022008=neurogenesis, 0032504=multicellular organism reproduction, 0006644=phospholipid metabolic process" 0005615=extracellular space anon-SAGE:Wang-122 "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG14034 16-Dec-15 2015_12 FBgn0026433 Grip128 Grip128 http://flybase.net/reports/FBgn0026433.html "FBgn0030644, FBtr0074075, FBpp0073891" protein_coding_gene 0043015=gamma-tubulin binding "0090307=mitotic spindle assembly, 0007067=mitotic nuclear division, 0045450=bicoid mRNA localization, 0007052=mitotic spindle organization, 0007112=male meiosis cytokinesis, 0007058=spindle assembly involved in female meiosis II, 0051298=centrosome duplication, 0051297=centrosome organization" "0005813=centrosome, 0008274=gamma-tubulin ring complex, 0000922=spindle pole" "grip, Dgrip128, grip128, CG9201, Dgrips128, DGrip128, GCP5" IPR007259=Gamma-tubulin complex component protein CG9201 16-Dec-15 2015_12 "viable,male sterile,female sterile,meiotic cell cycle defective,female,male,mitotic cell cycle defective" "egg,germline clone,Nebenkern,spermatid,S2 cell-line,spindle" FBgn0020846 l(2)108 lethal (2) 108 http://flybase.net/reports/FBgn0020846.html gene T(2;3)Hin108 16-Dec-15 2015_12 lethal FBgn0035805 CG7506 http://flybase.net/reports/FBgn0035805.html protein_coding_gene 0033615=mitochondrial proton-transporting ATP synthase complex assembly 0032592=integral component of mitochondrial membrane IPR009724=TMEM70 family CG7506 16-Dec-15 2015_12 WBGene00009330(F32D8.5) ENSMUSG00000025940(Tmem70) ENSG00000175606(TMEM70) FBgn0260868 CG42578 http://flybase.net/reports/FBgn0260868.html protein_coding_gene CG42578 16-Dec-15 2015_12 FBgn0027232 l(1)G0287 lethal (1) G0287 http://flybase.net/reports/FBgn0027232.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,chaeta" FBgn0039848 lox lysyl oxidase-like http://flybase.net/reports/FBgn0039848.html protein_coding_gene "0005044=scavenger receptor activity, 0005507=copper ion binding, 0004720=protein-lysine 6-oxidase activity" "0007155=cell adhesion, 0055114=oxidation-reduction process, 0006464=cellular protein modification process" 0016020=membrane "LOX, Lox, DmLOXL-1, dmlox-1, CG11335, Dmloxl-1" "IPR001695=Lysyl oxidase, IPR017448=SRCR-like domain, IPR001190=SRCR domain" CG11335 16-Dec-15 2015_12 "ENSDARG00000071676,ENSDARG00000071680(loxl5a),ENSDARG00000028412(loxl5b),ENSDARG00000003259" embryonic stage -- adult stage organism

viable FBgn0260856 Membrin Membrin http://flybase.net/reports/FBgn0260856.html "FBgn0044509, FBgn0035602, FBgn0062854" protein_coding_gene 0005484=SNAP receptor activity "0007430=terminal branching, open tracheal system, 0006909=phagocytosis, 0006891=intra-Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport, 0006906=vesicle fusion, 0060439=trachea morphogenesis" "0031201=SNARE complex, 0005794=Golgi apparatus" "SNARE/membrin, Memb, CG4780, membrin, moon cheese, fmembrin, BcDNA:SD22572" IPR027027=GOSR2/Membrin/Bos1 CG4780 16-Dec-15 2015_12 ENSDARG00000053070(gosr2) WBGene00007128(memb-1) ENSXETG00000014258(GOSR2) ENSMUSG00000020946(Gosr2) ENSG00000108433(GOSR2) DRSC10448 I 2.999240604 0.176904167 0.223094761 0.11073883 0.305016954 -0.307479355 FBgn0023073 l(1)19Fh lethal (1) 19Fh http://flybase.net/reports/FBgn0023073.html gene B2/45.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0262897 CR43252 http://flybase.net/reports/FBgn0262897.html non_protein_coding_gene CG43252 CR43252 16-Dec-15 2015_12 FBgn0037696 GstZ1 Glutathione S transferase Z1 http://flybase.net/reports/FBgn0037696.html protein_coding_gene "0016034=maleylacetoacetate isomerase activity, 0004364=glutathione transferase activity" "0006572=tyrosine catabolic process, 0006749=glutathione metabolic process, 0006559=L-phenylalanine catabolic process, 0009072=aromatic amino acid family metabolic process" 0005737=cytoplasm "gstz1, CG9362, GSTZ1" "IPR004046=Glutathione S-transferase, C-terminal, IPR005955=Maleylacetoacetate isomerase, IPR010987=Glutathione S-transferase, C-terminal-like, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal" CG9362 16-Dec-15 2015_12 ENSDARG00000027984(zgc:92869) "WBGene00001790(gst-42),WBGene00001791(gst-43),WBGene00021817(Y53G8B.1)" ENSXETG00000011079(GSTZ1) ENSMUSG00000021033(Gstz1) ENSG00000100577(GSTZ1) viable DRSC16478 E 0.07346915 0.783801614 2.116444809 1.416749745 -0.264658984 -0.801114694 FBgn0041833 Eth-AR310 Eth-AR310 http://flybase.net/reports/FBgn0041833.html gene Eth[AR]310 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0031762 CG9098 http://flybase.net/reports/FBgn0031762.html "FBtr0079228, FBpp0078859, FBtr0079229, FBpp0078860" protein_coding_gene "0005088=Ras guanyl-nucleotide exchange factor activity, 0005070=SH3/SH2 adaptor activity, 0005085=guanyl-nucleotide exchange factor activity" "0048812=neuron projection morphogenesis, 0046579=positive regulation of Ras protein signal transduction, 0007264=small GTPase mediated signal transduction" "IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR001660=Sterile alpha motif domain, IPR000980=SH2 domain, IPR023578=Ras guanine nucleotide exchange factor domain, IPR013761=Sterile alpha motif/pointed domain" CG9098 16-Dec-15 2015_12 "ENSDARG00000009081(sh2d3cb),ENSDARG00000028099(sh2d3ca),ENSDARG00000016981(bcar3)" "ENSXETG00000022008(SH2D3C),ENSXETG00000008226(bcar3)" "ENSMUSG00000059013(Sh2d3c),ENSMUSG00000028121(Bcar3)" "ENSG00000137936(BCAR3),ENSG00000095370(SH2D3C)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0029725 CG2871 http://flybase.net/reports/FBgn0029725.html protein_coding_gene CG2871 16-Dec-15 2015_12 FBgn0067880 Mod(Prat:bw)2-3 Mod(Prat:bw)2-3 http://flybase.net/reports/FBgn0067880.html gene Mod-2-3 16-Dec-15 2015_12 "developmental rate defective,dominant,lethal,recessive" FBgn0065544 l(2)SH1054 lethal (2) SH1054 http://flybase.net/reports/FBgn0065544.html gene l(2)SH2 1054 16-Dec-15 2015_12 "lethal,recessive" FBgn0020544 l(1)18DEa lethal (1) 18DEa http://flybase.net/reports/FBgn0020544.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0039172 Spase22-23 Spase 22/23-subunit http://flybase.net/reports/FBgn0039172.html protein_coding_gene 0008233=peptidase activity 0006465=signal peptide processing "0005787=signal peptidase complex, 0016021=integral component of membrane" "Spase22/23, CG5677" IPR007653=Signal peptidase 22kDa subunit CG5677 16-Dec-15 2015_12 ENSDARG00000069724 YLR066W(SPC3) WBGene00019679(K12H4.4) ENSXETG00000027917(SPCS3) "ENSMUSG00000054408(Spcs3),ENSMUSG00000048355,ENSMUSG00000048040" ENSG00000129128(SPCS3) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0025337 anon-58Ff anon-58Ff http://flybase.net/reports/FBgn0025337.html gene 1-May 16-Dec-15 2015_12 FBgn0011574 Csr Chaser http://flybase.net/reports/FBgn0011574.html gene 0035177=larval foraging behavior 16-Dec-15 2015_12 "behavior defective,dominant,viable" FBgn0038482 CG4053 http://flybase.net/reports/FBgn0038482.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP185 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG4053 16-Dec-15 2015_12 FBgn0082642 Outburst Outburst http://flybase.net/reports/FBgn0082642.html gene 0019991=septate junction assembly Ort 16-Dec-15 2015_12 FBgn0263664 CR43655 http://flybase.net/reports/FBgn0263664.html non_protein_coding_gene CR43655 16-Dec-15 2015_12 FBgn0000522 dwu dwarf unexpanded http://flybase.net/reports/FBgn0000522.html gene 16-Dec-15 2015_12 "visible,viable,poor,male fertile,reduced" "wing,adult abdomen,adult thorax" FBgn0261842 pre-mod(mdg4)-AE http://flybase.net/reports/FBgn0261842.html protein_coding_gene CG42774 "IPR007588=Zinc finger, FLYWCH-type" CG42774 16-Dec-15 2015_12 FBgn0035708 CG8398 http://flybase.net/reports/FBgn0035708.html FBgn0027687 protein_coding_gene anon-EST:Posey31 IPR011705=BTB/Kelch-associated CG8398 16-Dec-15 2015_12 viable FBgn0263904 l(3)CL62 http://flybase.net/reports/FBgn0263904.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0259575 GG01457 http://flybase.net/reports/FBgn0259575.html gene 16-Dec-15 2015_12 visible "wing vein,arista,unguis,tarsal segment" FBgn0046698 Pp1-Y2 "Protein phosphatase 1, Y-linked 2" http://flybase.net/reports/FBgn0046698.html "FBgn0058448, FBan0040448" protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" "DmPp1-Y2, Pp1-Y2, Pp1Y2, CG40448" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like" CG40448 16-Dec-15 2015_12 FBgn0037200 CG11109 http://flybase.net/reports/FBgn0037200.html protein_coding_gene "0008649=rRNA methyltransferase activity, 0003723=RNA binding" 0005730=nucleolus CT31087 "IPR018314=Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site, IPR015947=PUA-like domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR001678=SAM-dependent methyltransferase RsmB/NOP2-type, IPR023267=RNA (C5-cytosine) methyltransferase, IPR002478=PUA domain" CG11109 16-Dec-15 2015_12 ENSXETG00000022762(nsun6) ENSMUSG00000026707(Nsun6) ENSG00000152487 viable FBgn0033434 CG1902 http://flybase.net/reports/FBgn0033434.html protein_coding_gene "IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG1902 16-Dec-15 2015_12 "viable,fertile" FBgn0000819 fs(1)K1134 female sterile (1) K1134 http://flybase.net/reports/FBgn0000819.html gene 16-Dec-15 2015_12 "female sterile,recessive" "fat body,follicle cell" FBgn0044094 E(rst)D184 E(rst)D184 http://flybase.net/reports/FBgn0044094.html gene 0001745=compound eye morphogenesis D184 16-Dec-15 2015_12 viable eye FBgn0052086 CG32086 http://flybase.net/reports/FBgn0052086.html FBgn0036175 protein_coding_gene CG6100 CG32086 16-Dec-15 2015_12 ENSMUSG00000023931(Efhb) ENSG00000163576(EFHB) viable FBgn0040861 CG15722 http://flybase.net/reports/FBgn0040861.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267234 CR45674 http://flybase.net/reports/FBgn0267234.html non_protein_coding_gene CR45674 16-Dec-15 2015_12 FBgn0026650 l(2)50F7 lethal (2) 50F7 http://flybase.net/reports/FBgn0026650.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0032642 CG5110 http://flybase.net/reports/FBgn0032642.html FBgn0047173 protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0032947=protein complex scaffold" "0032006=regulation of TOR signaling, 0034613=cellular protein localization, 0071230=cellular response to amino acid stimulus" 0071986=Ragulator complex "dMP1, MP1, BcDNA:RE09173" IPR015019=Ragulator complex protein LAMTOR3 CG5110 16-Dec-15 2015_12 ENSDARG00000057075(mapksp1) ENSXETG00000026765(MAPKSP1) ENSMUSG00000059039(Gm5900) ENSG00000109270(LAMTOR3) "visible,heat sensitive,viable" "wing vein,ectopic,wing,heat sensitive" FBgn0028549 AT76-2A AT76-2A http://flybase.net/reports/FBgn0028549.html gene "2A, AT76" 16-Dec-15 2015_12 "lethal,recessive" FBgn0013384 acj8 abnormal-chemosensory-jump-8 http://flybase.net/reports/FBgn0013384.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive" FBgn0263589 CR43614 http://flybase.net/reports/FBgn0263589.html non_protein_coding_gene CR43614 16-Dec-15 2015_12 FBgn0052361 tRNA:CR32361 transfer RNA:CR32361 http://flybase.net/reports/FBgn0052361.html "FBgn0011907, FBgn0060159" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033420=CUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3L.trna41-LeuCAG, tRNA:L:CAG:AE002602-c, transfer RNA:leu2:66B, tRNA:L2:66B, CR32361, tRNA:leu2:66B, tRNA[Leu][[2]], AE002602.trna7-LeuCAG" CR32361 16-Dec-15 2015_12 FBgn0040574 CG5115 http://flybase.net/reports/FBgn0040574.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001857 l(1)TW1 lethal (1) TW1 http://flybase.net/reports/FBgn0001857.html gene 16-Dec-15 2015_12 "female sterile,lethal - all die before end of larval stage,cold sensitive,some die during larval stage" FBgn0010332 oho31 overgrown hematopoietic organs-31 http://flybase.net/reports/FBgn0010332.html FBgn0014274 gene 0006606=protein import into nucleus "l(2)k14401, l(2)oho31, oho-31, l(2)144/1" 16-Dec-15 2015_12 "lethal,recessive,hyperplasia,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,embryonic/larval lymph gland,embryonic/larval hemolymph,embryonic/larval central nervous system,embryonic/larval brain,gonad,testis,wing disc,haltere disc,ventral thoracic disc,eye-antennal disc,genital disc,ring gland" FBgn0015557 tor::tub tor::tub http://flybase.net/reports/FBgn0015557.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0261550 CG42668 http://flybase.net/reports/FBgn0261550.html "FBgn0038785, FBgn0038786" protein_coding_gene 0008142=oxysterol binding "CG15684, CG5077" "IPR000648=Oxysterol-binding protein, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR018494=Oxysterol-binding protein, conserved site, IPR001849=Pleckstrin homology domain" CG42668 16-Dec-15 2015_12 ENSDARG00000039724 ENSXETG00000013334(OSBPL8) "ENSMUSG00000020189(Osbpl8),ENSMUSG00000037606(Osbpl5)" "ENSG00000091039(OSBPL8),ENSG00000021762(OSBPL5)" FBgn0037548 CG7900 http://flybase.net/reports/FBgn0037548.html protein_coding_gene "0017064=fatty acid amide hydrolase activity, 0016884=carbon-nitrogen ligase activity, with glutamine as amido-N-donor" "IPR000120=Amidase, IPR023631=Amidase signature domain" CG7900 16-Dec-15 2015_12 YDR242W(AMD2) ENSMUSG00000034171(Faah) viable FBgn0003140 PpY-55A Protein phosphatase Y at 55A http://flybase.net/reports/FBgn0003140.html "FBgn0005781, FBgn0034285" protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation "0005634=nucleus, 0005737=cytoplasm" "Protein phosphatase D19, CG10930, PpD19, PPY, protein phosphatase from PCR fragment D19, DmPpY-55A, PPY 55A, protein phosphatase-Y, D19" "IPR029052=Metallo-dependent phosphatase-like, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG10930 16-Dec-15 2015_12 " spermatogenesis && adult stage , pupal stage " testis

" spermatogenesis && adult stage , larval stage , larval stage && S " " testis

, cyst cell

" viable FBgn0065464 l(2)SH1353 lethal (2) SH1353 http://flybase.net/reports/FBgn0065464.html gene l(2)SH2 1353 16-Dec-15 2015_12 "lethal,recessive" FBgn0033463 CG1513 http://flybase.net/reports/FBgn0033463.html protein_coding_gene 0008142=oxysterol binding "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR018494=Oxysterol-binding protein, conserved site, IPR000648=Oxysterol-binding protein" CG1513 16-Dec-15 2015_12 ENSDARG00000069298(osbpl9) WBGene00016331(obr-4) ENSXETG00000002831(OSBPL9) ENSMUSG00000028559(Osbpl9) ENSG00000117859(OSBPL9) viable DRSC06553 I -0.420651018 -1.687705469 -0.093259941 -0.014661411 1.103005431 1.340763635 FBgn0002717 mel melanized http://flybase.net/reports/FBgn0002717.html gene 16-Dec-15 2015_12 "viable,good,fertile,eye color defective,recessive,visible,body color defective" "pigment cell,wing,distal,trident" FBgn0259924 1A-RE 1A regulatory element http://flybase.net/reports/FBgn0259924.html insulator 16-Dec-15 2015_12 FBgn0085434 NaCP60E Na channel protein 60E http://flybase.net/reports/FBgn0085434.html "FBgn0016933, FBgn0002920, FBgn0035079" protein_coding_gene "0005248=voltage-gated sodium channel activity, 0022843=voltage-gated cation channel activity" "0006814=sodium ion transport, 0042048=olfactory behavior, 0035725=sodium ion transmembrane transport" "0001518=voltage-gated sodium channel complex, 0005886=plasma membrane" "dsc1, unnamed, CT24831, Sodium Channel 1, DSC1, DIC60, smi60E, DSC, CG34405, NaCP60E, Na-CP, DSCI, CG9071, dsc, Na-channel-protein, CG18506, put. sodium channel gene, smell impaired 60E" "IPR000048=IQ motif, EF-hand binding site, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR005821=Ion transport domain, IPR001696=Voltage gated sodium channel, alpha subunit, IPR028820=Sodium channel protein 60E" CG34405 16-Dec-15 2015_12 YGR217W(CCH1) FBgn0034725 CG6044 http://flybase.net/reports/FBgn0034725.html FBgn0064808 protein_coding_gene BcDNA:RH44966 "IPR003597=Immunoglobulin C1-set, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG6044 16-Dec-15 2015_12 viable DRSC04522 K -0.46880436 -0.29337005 -0.951804673 0.246273725 1.659626672 -0.320616216 FBgn0032375 CG14932 http://flybase.net/reports/FBgn0032375.html protein_coding_gene CG14932 16-Dec-15 2015_12 "viable,visible" "trichogen cell,supernumerary" FBgn0026649 l(2)61E5 lethal (2) 61E5 http://flybase.net/reports/FBgn0026649.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone,oocyte nucleus,nurse cell" FBgn0038447 CG14892 http://flybase.net/reports/FBgn0038447.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP175 "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG14892 16-Dec-15 2015_12 "ENSDARG00000059026(zgc:123217),ENSDARG00000071841,ENSDARG00000070897" ENSG00000186452(TMPRSS12) FBgn0029182 E(Khc)ek5 E(Khc)ek5 http://flybase.net/reports/FBgn0029182.html gene 16-Dec-15 2015_12 FBgn0262382 mir-1010 mir-1010 stem loop http://flybase.net/reports/FBgn0262382.html "FBgn0250806, FBgn0262198" miRNA_gene "dme-mir-1010, miR-1010, CR42905" CR42905 16-Dec-15 2015_12 viable FBgn0038301 CG6654 http://flybase.net/reports/FBgn0038301.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR016177=DNA-binding domain, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG6654 16-Dec-15 2015_12 WBGene00009448(zfp-2) FBgn0263965 BG02049 http://flybase.net/reports/FBgn0263965.html gene 16-Dec-15 2015_12 "long lived,female limited,starvation stress response defective,male limited,temperature response defective,gravitaxis defective" FBgn0060494 l(3)S108406 lethal (3) S108406 http://flybase.net/reports/FBgn0060494.html gene 1084/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0016028 l(3)89Ek lethal (3) 89Ek http://flybase.net/reports/FBgn0016028.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043036 l(2)42Bh lethal (2) 42Bh http://flybase.net/reports/FBgn0043036.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060919 l(3)S042532 lethal (3) S042532 http://flybase.net/reports/FBgn0060919.html gene 0425/32 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0024806 DIP2 DISCO Interacting Protein 2 http://flybase.net/reports/FBgn0024806.html FBgn0035119 protein_coding_gene "0003824=catalytic activity, 0008134=transcription factor binding, 0005515=protein binding" 0008152=metabolic process 0005634=nucleus "unnamed, CG7020, Ddip2" "IPR010506=DMAP1-binding, IPR000873=AMP-dependent synthetase/ligase" CG7020 16-Dec-15 2015_12 "ENSDARG00000062154(dip2c),ENSDARG00000025513(si:dkey-7l6.7),ENSDARG00000005350(dip2b),ENSDARG00000016348(LOC568954)" YOR093C() WBGene00017882(F28B3.1) ENSXETG00000007284(DIP2B) "ENSMUSG00000048264(Dip2c),ENSMUSG00000020231(Dip2a),ENSMUSG00000023026(Dip2b)" "ENSG00000151240(DIP2C),ENSG00000160305(DIP2A),ENSG00000066084(DIP2B)" "viable,fertile" FBgn0259438 EP-167 http://flybase.net/reports/FBgn0259438.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing" FBgn0019678 mor(1)13 mortality gene (1)13 http://flybase.net/reports/FBgn0019678.html gene 16-Dec-15 2015_12 short lived FBgn0033164 CG11112 http://flybase.net/reports/FBgn0033164.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CT8227 CG11112 16-Dec-15 2015_12 viable DRSC05049 K 0.960574932 0.103053173 1.257624988 -1.302258417 -1.307054443 -1.572465754 FBgn0020928 Hsf::Hsap\HSF1 HSF1 http://flybase.net/reports/FBgn0020928.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0051414 CG31414 http://flybase.net/reports/FBgn0051414.html FBgn0039105 protein_coding_gene 0004348=glucosylceramidase activity "0006665=sphingolipid metabolic process, 0005975=carbohydrate metabolic process, 0034620=cellular response to unfolded protein" "unnamed, CG10299, Glucosylceramidase" "IPR017853=Glycoside hydrolase superfamily, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR013781=Glycoside hydrolase, catalytic domain, IPR001139=Glycoside hydrolase, family 30" CG31414 16-Dec-15 2015_12 "WBGene00021160(Y4C6B.6),WBGene00008706(F11E6.1),WBGene00016335(C33C12.3),WBGene00016340(C33C12.8)" ENSMUSG00000028048(Gba) "ENSG00000177628(GBA),ENSG00000160766" viable FBgn0010165 psb pseudobeadex http://flybase.net/reports/FBgn0010165.html gene 16-Dec-15 2015_12 FBgn0260064 2L3500 http://flybase.net/reports/FBgn0260064.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0265833 CG44622 http://flybase.net/reports/FBgn0265833.html protein_coding_gene lincRNA.354 CG44622 16-Dec-15 2015_12 FBgn0032790 CG10194 http://flybase.net/reports/FBgn0032790.html protein_coding_gene 0016787=hydrolase activity 0006909=phagocytosis "IPR015797=NUDIX hydrolase domain-like, IPR000086=NUDIX hydrolase domain" CG10194 16-Dec-15 2015_12 WBGene00003584(ndx-7) ENSXETG00000025567(BC075322.1) ENSMUSG00000034875(Nudt19) ENSG00000213965(NUDT19) viable FBgn0026785 P29 P29 http://flybase.net/reports/FBgn0026785.html gene 16-Dec-15 2015_12 "visible,dominant,viable" postorbital bristle FBgn0051357 CG31357 http://flybase.net/reports/FBgn0051357.html FBgn0039231 protein_coding_gene CG13638 "IPR024964=CTLH/CRA C-terminal to LisH motif domain, IPR006595=CTLH, C-terminal LisH motif, IPR013144=CRA domain, IPR006594=LIS1 homology motif" CG31357 16-Dec-15 2015_12 ENSDARG00000053691(maea) YIL097W(FYV10) WBGene00012366(W09G3.2) ENSXETG00000010676(Q66KB4_XENTR) ENSMUSG00000079562(Maea) ENSG00000090316(MAEA) "viable,fertile" FBgn0044424 M80-A32 M80-A32 http://flybase.net/reports/FBgn0044424.html gene "0042067=establishment of ommatidial planar polarity, 0001754=eye photoreceptor cell differentiation" M80#A32 16-Dec-15 2015_12 lethal "eye photoreceptor cell,somatic clone,photoreceptor cell R4,cell autonomous" FBgn0085248 CG34219 http://flybase.net/reports/FBgn0085248.html protein_coding_gene CG34219 16-Dec-15 2015_12 FBgn0002164 l(2)Sp8 lethal (2) Sp8 http://flybase.net/reports/FBgn0002164.html gene 16-Dec-15 2015_12 lethal FBgn0250815 Jon65Aiv Jonah 65Aiv http://flybase.net/reports/FBgn0250815.html "FBgn0035664, FBgn0001286, FBgn0046283" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "Jon65, SP117, jon65aiv, Jon65A, CG6467, Jonah65A-IV, Jonah 65A, BEST:GH23808" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG6467 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" FBgn0069919 CG41133 http://flybase.net/reports/FBgn0069919.html FBan0041133 protein_coding_gene 16-Dec-15 2015_12 FBgn0028257 l(3)72Dq lethal (3) 72Dq http://flybase.net/reports/FBgn0028257.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033265 coil coilin http://flybase.net/reports/FBgn0033265.html protein_coding_gene 0030576=Cajal body organization "0015030=Cajal body, 0035363=histone locus body, 0016604=nuclear body, 0005654=nucleoplasm" "coil, Coilin, coilin, CG8710, dcoilin" CG8710 16-Dec-15 2015_12 "viable,fertile" Cajal body FBgn0003295 ru roughoid http://flybase.net/reports/FBgn0003295.html "FBgn0035215, FBgn0041724" protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" "0001752=compound eye photoreceptor fate commitment, 0042676=compound eye cone cell fate commitment, 0050714=positive regulation of protein secretion, 0007479=leg disc proximal/distal pattern formation, 0001745=compound eye morphogenesis, 0007173=epidermal growth factor receptor signaling pathway, 0007427=epithelial cell migration, open tracheal system, 0006508=proteolysis, 0003015=heart process" "0005886=plasma membrane, 0005783=endoplasmic reticulum, 0045177=apical part of cell, 0016021=integral component of membrane, 0005887=integral component of plasma membrane" "rhomboid-3, rhomboid, roughoid/rhomboid-3, Roughoid, rho-3, Rho-3, Rho-related [62A1], CG1214, Rhomboid 3, Rhomboid-3, rho3, rhomboid 3" "IPR017213=Peptidase S54, rhomboid, metazoan, IPR002610=Peptidase S54, rhomboid, IPR022764=Peptidase S54, rhomboid domain" CG1214 16-Dec-15 2015_12 "wild-type,cell polarity defective,planar polarity defective,recessive,visible,neuroanatomy defective,neurophysiology defective,viable" "embryonic/larval ganglionic branch,eye,ommatidium,photoreceptor,cone cell,pigment cell,adult heart chamber,ganglionic branch 1,eye photoreceptor cell,optic cartridge,wing,wing vein,ectopic,egg" FBgn0086024 snoRNA:Me28S-A2589b http://flybase.net/reports/FBgn0086024.html snoRNA_gene "Me28S-Am2589b, CR34653" CR34653 16-Dec-15 2015_12 FBgn0262223 mir-994 mir-994 stem loop http://flybase.net/reports/FBgn0262223.html miRNA_gene "miR-994, dme-mir-994, CR42930" CR42930 16-Dec-15 2015_12 lethal FBgn0019751 l(1)815-23 lethal (1) 815-23 http://flybase.net/reports/FBgn0019751.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031168 CG1722 http://flybase.net/reports/FBgn0031168.html protein_coding_gene CG1722 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0264882 CR44073 http://flybase.net/reports/FBgn0264882.html non_protein_coding_gene CR44073 16-Dec-15 2015_12 FBgn0039868 CG11563 http://flybase.net/reports/FBgn0039868.html FBgn0063068 protein_coding_gene BcDNA:RE07994 IPR019002=Ribosome biogenesis protein Nop16 CG11563 16-Dec-15 2015_12 ENSDARG00000044402(nop16) WBGene00013958(ZK265.6) ENSXETG00000022342(TNeu075c08.1) ENSMUSG00000025869(Nop16) "viable,fertile" FBgn0264309 CG43784 http://flybase.net/reports/FBgn0264309.html protein_coding_gene CR43784 CG43784 16-Dec-15 2015_12 FBgn0002211 l(3)67BDi lethal (3) 67BDi http://flybase.net/reports/FBgn0002211.html gene 16-Dec-15 2015_12 lethal FBgn0016898 l(3)64Ch lethal (3) 64Ch http://flybase.net/reports/FBgn0016898.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044498 DTD44.5 DTD44.5 http://flybase.net/reports/FBgn0044498.html gene 16-Dec-15 2015_12 viable FBgn0250739 l(3)S026915 lethal (3) S026915 http://flybase.net/reports/FBgn0250739.html gene l(3)s026915 16-Dec-15 2015_12 lethal FBgn0266816 CR45278 http://flybase.net/reports/FBgn0266816.html non_protein_coding_gene CR45278 16-Dec-15 2015_12 FBgn0031098 CG17068 http://flybase.net/reports/FBgn0031098.html protein_coding_gene "IPR011705=BTB/Kelch-associated, IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG17068 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0267116 CR45556 http://flybase.net/reports/FBgn0267116.html non_protein_coding_gene CR45556 16-Dec-15 2015_12 FBgn0001559 l(1)19Da lethal (1) 19Da http://flybase.net/reports/FBgn0001559.html gene 16-Dec-15 2015_12 lethal FBgn0005086 fs(2)OW810 female sterile (2) OW810 http://flybase.net/reports/FBgn0005086.html gene 16-Dec-15 2015_12 FBgn0052590 CG32590 http://flybase.net/reports/FBgn0052590.html protein_coding_gene IPR019320=Uncharacterised protein family UPF0402 CG32590 16-Dec-15 2015_12 ENSDARG00000071339(mef2b) WBGene00010767(K11B4.2) ENSXETG00000013043() ENSMUSG00000002345(2310045N01Rik) FBgn0062563 P12 P12 http://flybase.net/reports/FBgn0062563.html gene 16-Dec-15 2015_12 FBgn0001113 glide glide http://flybase.net/reports/FBgn0001113.html gene gli 16-Dec-15 2015_12 "visible,viable,male,reduced,male sterile,recessive" "wing,tergite" FBgn0005653 Mst59Dc Male-specific transcript 59Dc http://flybase.net/reports/FBgn0005653.html gene 16-Dec-15 2015_12 FBgn0025489 l(3)82EFb lethal (3) 82EFb http://flybase.net/reports/FBgn0025489.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015973 l(2)PC4-427 lethal (2) PC4-427 http://flybase.net/reports/FBgn0015973.html gene l(2)PC4-M 16-Dec-15 2015_12 "lethal,recessive" FBgn0028044 l(3)S097907a lethal (3) S097907a http://flybase.net/reports/FBgn0028044.html FBgn0029010 gene "unnamed, 762/1, 1412/03, 1429/10, 979/7, l(3)S097907, 1285/01, 0183/01, 0979/07, 0677/12, 1125/17, 1227/09, 0741/07" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of prepupal stage,some die during prepupal stage" FBgn0033115 Spn42De Serpin 42De http://flybase.net/reports/FBgn0033115.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0010951=negative regulation of endopeptidase activity, 0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis" 0005615=extracellular space CG9460 "IPR000215=Serpin family, IPR023795=Serpin, conserved site, IPR023796=Serpin domain" CG9460 16-Dec-15 2015_12 ENSDARG00000034168(serpini1) "WBGene00005643(srp-2),WBGene00005648(srp-7),WBGene00005647(srp-6),WBGene00005644(srp-3),WBGene00005642(srp-1)" ENSXETG00000022866(SERPINI1) "ENSMUSG00000027834(Serpini1),ENSMUSG00000034139(Serpini2)" "ENSG00000163536(SERPINI1),ENSG00000114204(SERPINI2)" viable FBgn0014114 anon-84Bc anon-84Bc http://flybase.net/reports/FBgn0014114.html gene Y2 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage && larval stage && pupal stage " unfertilized egg

FBgn0034897 Sesn Sestrin http://flybase.net/reports/FBgn0034897.html "FBgn0045816, FBgn0063233" protein_coding_gene "0000422=mitochondrion degradation, 0002121=inter-male aggressive behavior, 2000377=regulation of reactive oxygen species metabolic process, 0010259=multicellular organismal aging, 1901031=regulation of response to reactive oxygen species, 0030308=negative regulation of cell growth" 0005634=nucleus "CG11299, BcDNA:GH20113, dSesn, sestrin, BEST:GH20113" "IPR029032=AhpD-like, IPR006730=Sestrin" CG11299 16-Dec-15 2015_12 "ENSDARG00000020693(sesn1),ENSDARG00000015822(sesn3),ENSDARG00000070012(sesn2),ENSDARG00000071547" WBGene00022279(sesn-1) "ENSXETG00000007079(sesn3),ENSXETG00000021286(SESN1),ENSXETG00000020657(sesn2)" "ENSMUSG00000032009(Sesn3),ENSMUSG00000038332(Sesn1),ENSMUSG00000028893(Sesn2)" "ENSG00000080546(SESN1),ENSG00000149212(SESN3),ENSG00000130766(SESN2)" "aging defective,visible,cell growth defective,viable,behavior defective,recessive" "myofibril,sarcomere,M band,Z disc,actomyosin,mitochondrion,wing blade" FBgn0267372 T:KASH-Msp300 KASH domain of Msp300 http://flybase.net/reports/FBgn0267372.html engineered_tag 16-Dec-15 2015_12 FBgn0045848 l(4)102Fe lethal (4) 102Fe http://flybase.net/reports/FBgn0045848.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265427 CR44339 http://flybase.net/reports/FBgn0265427.html non_protein_coding_gene lincRNA.296 CR44339 16-Dec-15 2015_12 FBgn0025009 E(tkv)D1 E(tkv)D1 http://flybase.net/reports/FBgn0025009.html gene D1 16-Dec-15 2015_12 FBgn0031149 CG1518 http://flybase.net/reports/FBgn0031149.html protein_coding_gene 0004576=oligosaccharyl transferase activity "0022416=chaeta development, 0035220=wing disc development, 0006486=protein glycosylation" "0016020=membrane, 0012505=endomembrane system" STT "IPR003674=Oligosaccharyl transferase, STT3 subunit" CG1518 16-Dec-15 2015_12 YGL022W(STT3) ENSXETG00000017775(itm1) ENSMUSG00000032116(Stt3a) ENSG00000134910(STT3A) "viable,visible" mesothoracic tergum FBgn0033240 CG2906 http://flybase.net/reports/FBgn0033240.html protein_coding_gene IPR025714=Methyltransferase domain CG2906 16-Dec-15 2015_12 WBGene00009123(F25H2.12) "ENSXETG00000019930(TEgg125j18.1),ENSXETG00000014982()" ENSMUSG00000004896(BC023814) ENSG00000143303(RRNAD1) viable DRSC06841 K -0.406639442 0.834796788 -0.53155024 0.643191129 -1.181227739 -1.605465623 FBgn0001899 l(2)21Fe lethal (2) 21Fe http://flybase.net/reports/FBgn0001899.html gene "l(2)neh-13, l(2)neh13" 16-Dec-15 2015_12 lethal FBgn0005094 fs(2)OWc6 female sterile (2) OWc6 http://flybase.net/reports/FBgn0005094.html gene 16-Dec-15 2015_12 FBgn0001880 l(1)YE17 lethal (1) YE17 http://flybase.net/reports/FBgn0001880.html gene 16-Dec-15 2015_12 lethal FBgn0085646 CG41427 http://flybase.net/reports/FBgn0085646.html FBan0041427 protein_coding_gene 16-Dec-15 2015_12 FBgn0047092 CR32730 http://flybase.net/reports/FBgn0047092.html FBgn0052730 non_protein_coding_gene "MRE32, BcDNA:RE54930, mRNA-like ncRNA in embryogenesis 3e" CR32730 16-Dec-15 2015_12 DRSC22957 I 1.998860757 0.55375019 0.130235958 1.236300078 -0.313156906 0.463148486 FBgn0010453 Wnt4 Wnt oncogene analog 4 http://flybase.net/reports/FBgn0010453.html protein_coding_gene "0001664=G-protein coupled receptor binding, 0005515=protein binding, 0005102=receptor binding, 0005109=frizzled binding" "0016055=Wnt signaling pathway, 0009952=anterior/posterior pattern specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0008045=motor neuron axon guidance, 0042067=establishment of ommatidial planar polarity, 0035206=regulation of hemocyte proliferation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0016477=cell migration, 0031290=retinal ganglion cell axon guidance, 0060071=Wnt signaling pathway, planar cell polarity pathway, 0008585=female gonad development, 0003407=neural retina development, 0007435=salivary gland morphogenesis, 0009798=axis specification, 0016201=synaptic target inhibition, 0060070=canonical Wnt signaling pathway, 0035567=non-canonical Wnt signaling pathway" "0005576=extracellular region, 0009986=cell surface, 0005615=extracellular space, 0005886=plasma membrane" "wnt-4, anon-EST:Liang-2.4, DWnt4, wnt4, Wnt, Wnt-4, clone 2.4, CG4698, Dwnt4, Dm DWnt4, DWnt-4" "IPR005817=Wnt, IPR018161=Wnt protein, conserved site" CG4698 16-Dec-15 2015_12 "ENSMUSG00000018486(Wnt9b),ENSMUSG00000000126(Wnt9a)" "ENSG00000158955(WNT9B),ENSG00000143816(WNT9A)" " embryonic stage | stage 14 , embryonic stage , embryonic stage | stage 8-11 , embryonic stage | stage 16 " " embryonic/larval foregut

, parasegment 4 &&of visceral mesoderm

, ectoderm

,

segment polarity , embryonic/larval hindgut

, embryonic central nervous system

, gastric caecum

, parasegment 8 &&of visceral mesoderm

, midgut constriction 2

" " adult stage , pupal stage " " terminal filament basal cell

, epithelial sheath

, germarium region 2

, germarium region 1

" "neuroanatomy defective,sterile,recessive,partially lethal - majority die,some die during larval stage,visible,lethal,heat sensitive,planar polarity defective,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,viable,partially" "lamina,neuron,eye photoreceptor cell,denticle row 1,denticle row 2,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,abdominal segment 9,abdominal segment 10,abdominal segment 11,abdominal segment,embryonic/larval optic stalk,presumptive embryonic salivary gland,ovary,germarium,egg chamber,ovarian sheath,ovariole,denticle,ectopic,embryonic/first instar larval cuticle,embryonic epidermis,dorsal,dorsal denticle,denticle belt,wing,heat sensitive,scutellum,mesothoracic tergum,wing margin bristle,wing sensillum,alula,haltere,wing disc,sternopleural bristle,supernumerary,dorsocentral bristle,posterior postalar bristle,scutellar bristle,anterior crossvein,wing hair,cell non-autonomous,somatic clone,embryonic ventral epidermis,eye equator,wing vein,eye,ventral compartment,ommatidium" DRSC00976 K -0.640386697 -1.39388873 0.564039281 -0.709771696 1.176869013 1.648467388 FBgn0027057 CSN1b COP9 signalosome subunit 1b http://flybase.net/reports/FBgn0027057.html protein_coding_gene "0010388=cullin deneddylation, 0008277=regulation of G-protein coupled receptor protein signaling pathway, 0048142=germarium-derived cystoblast division, 0007281=germ cell development, 0007095=mitotic G2 DNA damage checkpoint, 0048140=male germ-line cyst encapsulation, 0051726=regulation of cell cycle, 0022008=neurogenesis, 0050821=protein stabilization, 0046331=lateral inhibition, 0036099=female germ-line stem cell maintenance" 0008180=COP9 signalosome "dCSN1, DCH1-2, Csn1b, Dch1-2, CG3889, CH1-2, csn1, Csn1B, COP9 complex homolog subunit 1 b, CSN1B, COP9 complex homolog subunit 1-2, CSN1, Drosophila COP9 signalosome homolog 1, Dch1" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019585=26S proteasome, regulatory subunit Rpn7, IPR000717=Proteasome component (PCI) domain" CG3889 16-Dec-15 2015_12 ENSDARG00000040650(gps1) WBGene00000813(csn-1) ENSXETG00000019653(gps1) ENSMUSG00000025156(Gps1) ENSG00000169727(GPS1) "viable,fertile,visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "wing,arista,sex comb,leg,embryonic/larval neuroblast,ganglion mother cell,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0035405 CG15812 http://flybase.net/reports/FBgn0035405.html protein_coding_gene 0003677=DNA binding "0006338=chromatin remodeling, 0022008=neurogenesis" "0005634=nucleus, 0005700=polytene chromosome" "pfk, Pfk, CG15812, piefke" "IPR007889=DNA binding HTH domain, Psq-type, IPR000210=BTB/POZ domain, IPR009057=Homeodomain-like, IPR011333=POZ domain" CG15812 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible,body color defective" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0014106 anon-4Ce anon-4Ce http://flybase.net/reports/FBgn0014106.html gene "Transcript 15, T15" 16-Dec-15 2015_12 FBgn0267010 CR45454 http://flybase.net/reports/FBgn0267010.html non_protein_coding_gene CR45454 16-Dec-15 2015_12 FBgn0002590 RpS5a Ribosomal protein S5a http://flybase.net/reports/FBgn0002590.html protein_coding_gene "0003723=RNA binding, 0003735=structural constituent of ribosome" "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0000228=nuclear chromosome, 0022627=cytosolic small ribosomal subunit, 0005840=ribosome, 0005730=nucleolus, 0005737=cytoplasm" "S5a, M(1)15d, ribosomal protein S5 gene, Minute 1(o), RpS5, RS5A_DROME, ribosomal protein S5a, M(1)34i28, M(1)o, M[[o]], CG8922, Minute(1)15D, rps5, rpS5, Ribosomal protein S5, transcript e, Rp S5a, M(1)15D, RS5" "IPR000235=Ribosomal protein S5/S7, IPR023798=Ribosomal protein S7 domain, IPR005716=Ribosomal protein S5/S7, eukaryotic/archaeal, IPR020606=Ribosomal protein S7, conserved site" CG8922 16-Dec-15 2015_12 ENSDARG00000043453(rps5) YJR123W(RPS5) WBGene00004474(rps-5) ENSXETG00000020355(rps5) ENSMUSG00000012848(Rps5) ENSG00000083845(RPS5) "developmental rate defective,dominant,visible,Minute,size defective,lethal" "macrochaeta,adult heart" DRSC20282 EK -0.585595634 -0.575191348 0.17520749 -2.178272914 1.635791469 3.410494314 FBgn0266489 CG45088 http://flybase.net/reports/FBgn0266489.html protein_coding_gene Dromel_CG6191_FBtr0087678_uORF CG45088 16-Dec-15 2015_12 FBgn0264775 CG44013 http://flybase.net/reports/FBgn0264775.html FBgn0038346 protein_coding_gene CG14872 "IPR011038=Calycin-like, IPR012674=Calycin" CG44013 16-Dec-15 2015_12 FBgn0005468 l(1)ts178 lethal (1) ts178 http://flybase.net/reports/FBgn0005468.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0062412 Ctr1B Copper transporter 1B http://flybase.net/reports/FBgn0062412.html FBgn0037575 protein_coding_gene "0015088=copper uptake transmembrane transporter activity, 0005375=copper ion transmembrane transporter activity" "0006825=copper ion transport, 0010038=response to metal ion, 0006878=cellular copper ion homeostasis, 0035434=copper ion transmembrane transport" "0005886=plasma membrane, 0016021=integral component of membrane" "ctr1B, CG7459" IPR007274=Ctr copper transporter CG7459 16-Dec-15 2015_12 "visible,lethal,conditional,recessive,body color defective,chemical sensitive,partially lethal - majority die,viable" "eye,chemical conditional,adult cuticle,conditional" FBgn0260315 GSd410 http://flybase.net/reports/FBgn0260315.html gene 16-Dec-15 2015_12 lethal FBgn0039886 CG2003 http://flybase.net/reports/FBgn0039886.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG2003 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "mitotic cell cycle defective,viable" FBgn0032521 CG7110 http://flybase.net/reports/FBgn0032521.html protein_coding_gene CG7110 16-Dec-15 2015_12 "viable,fertile" FBgn0036980 RhoBTB Rho-related BTB domain containing http://flybase.net/reports/FBgn0036980.html "FBgn0040289, FBgn0041190" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0035011=melanotic encapsulation of foreign target, 0007264=small GTPase mediated signal transduction" 0005622=intracellular "RhoBTB, RhoX, CG5701, RhoGTPase, 28574635" "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type" CG5701 16-Dec-15 2015_12 ENSDARG00000016868(rhobtb2a) "ENSXETG00000003124(RHOBTB1),ENSXETG00000010513(RHOBTB2)" "ENSMUSG00000022075(Rhobtb2),ENSMUSG00000019944(Rhobtb1)" "ENSG00000008853(RHOBTB2),ENSG00000072422(RHOBTB1)" immune response defective FBgn0261727 EC549 http://flybase.net/reports/FBgn0261727.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085664 CR41519 http://flybase.net/reports/FBgn0085664.html FBan0041519 pseudogene_attribute CG41519 CR41519 16-Dec-15 2015_12 FBgn0058367 CG40367 http://flybase.net/reports/FBgn0058367.html protein_coding_gene 16-Dec-15 2015_12 FBgn0084021 CG41459 http://flybase.net/reports/FBgn0084021.html FBan0041459 protein_coding_gene 16-Dec-15 2015_12 FBgn0060784 l(3)S059813 lethal (3) S059813 http://flybase.net/reports/FBgn0060784.html gene 0598/13 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038629 CG14304 http://flybase.net/reports/FBgn0038629.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14304 16-Dec-15 2015_12 "viable,fertile" FBgn0060609 l(3)S090405b lethal (3) S090405b http://flybase.net/reports/FBgn0060609.html gene 0904/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0001773 l(1)M47 lethal (1) M47 http://flybase.net/reports/FBgn0001773.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0267918 CR46199 http://flybase.net/reports/FBgn0267918.html non_protein_coding_gene lincRNA.782 CR46199 16-Dec-15 2015_12 FBgn0051633 CG31633 http://flybase.net/reports/FBgn0051633.html FBgn0031843 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "CG13770, FBXL17" CG31633 16-Dec-15 2015_12 WBGene00007168(B0393.3) FBgn0053110 CG33110 http://flybase.net/reports/FBgn0053110.html "FBgn0038987, FBgn0038988" protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane "CG6926, CG13844" IPR002076=ELO family CG33110 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263776 CG43693 http://flybase.net/reports/FBgn0263776.html "FBgn0036115, FBgn0085268" protein_coding_gene "CG34239, CG6327" "IPR013057=Amino acid transporter, transmembrane domain" CG43693 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "WBGene00012804(Y43F4B.7),WBGene00020837(T27A1.5)" "ENSXETG00000017123(SLC36A4),ENSXETG00000019424()" "ENSMUSG00000043885(Slc36a4),ENSMUSG00000020261(Slc36a1),ENSMUSG00000020264(Slc36a2),ENSMUSG00000049491(Slc36a3)" "ENSG00000123643(SLC36A1),ENSG00000186335(SLC36A2),ENSG00000186334(SLC36A3),ENSG00000180773(SLC36A4)" FBgn0060882 l(3)S044835a lethal (3) S044835a http://flybase.net/reports/FBgn0060882.html gene 0448/35 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052034 tRNA:T:ë¬ transfer RNA:thr:pseudogene http://flybase.net/reports/FBgn0052034.html FBgn0060050 pseudogene_attribute 0033437=ACU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR32034, chr3L.trna21-ThrAGT, tRNA:TPsi:AGT:AE002602, AE002602.trna15-ThrAGT, tRNA:CR32034, transfer RNA:CR32034" CR32034 16-Dec-15 2015_12 FBgn0014065 Su(tor)3-307 Su(tor)3-307 http://flybase.net/reports/FBgn0014065.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0023138 WppE White prepupal locus E http://flybase.net/reports/FBgn0023138.html gene "14, 21, 7" 16-Dec-15 2015_12 FBgn0067731 l(1)R-8-18 lethal (1) R-8-18 http://flybase.net/reports/FBgn0067731.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060802 l(3)S057114b lethal (3) S057114b http://flybase.net/reports/FBgn0060802.html gene 0571/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267477 CR45827 http://flybase.net/reports/FBgn0267477.html non_protein_coding_gene CR45827 16-Dec-15 2015_12 FBgn0060826 l(3)S051302 lethal (3) S051302 http://flybase.net/reports/FBgn0060826.html gene 0513/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0028699 Rh50 Rh50 http://flybase.net/reports/FBgn0028699.html "FBgn0028502, FBgn0029132" protein_coding_gene 0008519=ammonium transmembrane transporter activity 0015696=ammonium transport 0016020=membrane "Rh-like, CG7499, BcDNA:GH03016" "IPR024041=Ammonium transporter AmtB-like domain, IPR029020=Ammonium/urea transporter, IPR002229=Blood group Rhesus C/E/D polypeptide" CG7499 16-Dec-15 2015_12 "ENSDARG00000009018(rhbg),ENSDARG00000029066(LOC100332792),ENSDARG00000003203(zgc:162132),ENSDARG00000007080(rhcg2a),ENSDARG00000019253(rhag),ENSDARG00000041848(rh50)" WBGene00004358(rhr-1) "ENSXETG00000019898(rhbg),ENSXETG00000017762(rhcg)" "ENSMUSG00000001417(Rhbg),ENSMUSG00000030549(Rhcg)" "ENSG00000140519(RHCG),ENSG00000112077(RHAG),ENSG00000132677(RHBG)" viable FBgn0266748 CR45221 http://flybase.net/reports/FBgn0266748.html non_protein_coding_gene CR45221 16-Dec-15 2015_12 FBgn0015892 anon-84Fa T2 transcript http://flybase.net/reports/FBgn0015892.html gene T2 16-Dec-15 2015_12 FBgn0019776 l(1)32 lethal (1) 32 http://flybase.net/reports/FBgn0019776.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034694 CG6613 http://flybase.net/reports/FBgn0034694.html protein_coding_gene "0008270=zinc ion binding, 0019992=diacylglycerol binding" 0035556=intracellular signal transduction "IPR025258=Putative zinc-RING and/or ribbon, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001841=Zinc finger, RING-type, IPR004012=RUN domain" CG6613 16-Dec-15 2015_12 ENSDARG00000063247(zgc:158281) ENSXETG00000003468() ENSMUSG00000034247(Plekhm1) ENSG00000141342 viable FBgn0041623 Or65c Odorant receptor 65c http://flybase.net/reports/FBgn0041623.html "FBgn0052403, FBtr0077006, FBpp0076714" protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" 0007608=sensory perception of smell "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR65, CG32403, LU27.3, 65c" "IPR004117=Olfactory receptor, Drosophila" CG32403 16-Dec-15 2015_12 viable FBgn0035090 CG2736 http://flybase.net/reports/FBgn0035090.html protein_coding_gene 0005044=scavenger receptor activity "0006952=defense response, 0007155=cell adhesion" "0005811=lipid particle, 0005887=integral component of plasma membrane, 0016020=membrane" cg2736 IPR002159=CD36 antigen CG2736 16-Dec-15 2015_12 "viable,fertile" DRSC04314 E 0.488191256 0.053859534 1.534127731 -0.004317665 -0.416692636 -0.409543202 FBgn0263971 CG43725 http://flybase.net/reports/FBgn0263971.html protein_coding_gene CG43725 16-Dec-15 2015_12 FBgn0051363 Jupiter Jupiter http://flybase.net/reports/FBgn0051363.html "FBgn0025976, FBgn0037919, FBgn0042108, FBgn0042109, FBgn0044704, FBgn0045776, FBgn0063691, FBgn0064799, FBgn0064919, FBgn0064972" protein_coding_gene "0046872=metal ion binding, 0005200=structural constituent of cytoskeleton, 0003676=nucleic acid binding, 0008017=microtubule binding" 0031116=positive regulation of microtubule polymerization "0005875=microtubule associated complex, 0005874=microtubule, 0005634=nucleus, 0015630=microtubule cytoskeleton, 0005829=cytosol" "CG18763, clone 1.76, BEST:LP05168, CG31363, CG17238, jupiter, BcDNA:LD43690, BcDNA:RH53211, anon-WO0140519.173, BcDNA:GH06373, CG18762, anon-EST:Liang-1.76, BcDNA:LD21358" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG31363 16-Dec-15 2015_12 "ENSDARG00000054002(hn1),ENSDARG00000029419(zgc:73237)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0083027 snoRNA:ë¬18S-531 snoRNA:ë¬18S-531 http://flybase.net/reports/FBgn0083027.html snoRNA_gene "chrX:619903..620074, Psi18S-531, psi18S-531, Psi 18S-531, CR34590" CR34590 16-Dec-15 2015_12 FBgn0027986 l(3)S132413 lethal (3) S132413 http://flybase.net/reports/FBgn0027986.html gene 1324/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0260270 GSd454 http://flybase.net/reports/FBgn0260270.html gene 16-Dec-15 2015_12 lethal FBgn0065550 l(2)SH1036 lethal (2) SH1036 http://flybase.net/reports/FBgn0065550.html gene l(2)SH2 1036 16-Dec-15 2015_12 "lethal,recessive" FBgn0260744 Tango9 Transport and Golgi organization 9 http://flybase.net/reports/FBgn0260744.html "FBgn0037971, FBgn0015346" protein_coding_gene "0008284=positive regulation of cell proliferation, 0009306=protein secretion, 1901029=negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway" "0005739=mitochondrion, 0016021=integral component of membrane, 0005794=Golgi apparatus" "87A7-9/5, TANGO9, anon-87Ad, CG10007" IPR012404=Nucleotide-sugar transporter-related CG10007 16-Dec-15 2015_12 ENSDARG00000016745(zgc:92765) WBGene00016235(C29H12.2) ENSXETG00000003331(C2orf18) ENSMUSG00000029175(4930471M23Rik) ENSG00000213699(C2orf18) FBgn0004746 l(3)85Fc lethal (3) 85Fc http://flybase.net/reports/FBgn0004746.html gene 16-Dec-15 2015_12 lethal FBgn0065190 l(2)SH2334 lethal (2) SH2334 http://flybase.net/reports/FBgn0065190.html gene l(2)SH2 2334 16-Dec-15 2015_12 "lethal,recessive" FBgn0014227 l(2)31Ef lethal (2) 31Ef http://flybase.net/reports/FBgn0014227.html gene 31Ef 16-Dec-15 2015_12 "lethal,recessive" FBgn0036781 CG13699 http://flybase.net/reports/FBgn0036781.html protein_coding_gene CG13699 16-Dec-15 2015_12 "viable,fertile" FBgn0033864 CG18368 http://flybase.net/reports/FBgn0033864.html protein_coding_gene CG18368 16-Dec-15 2015_12 viable FBgn0063493 GstE7 Glutathione S transferase E7 http://flybase.net/reports/FBgn0063493.html FBgn0034341 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "Glutathione S-transferase, gstE7, glutathione transferase E7, E7, GST-E7, DmGSTE7, CG17531, GSTE7, gste7" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG17531 16-Dec-15 2015_12 YLL060C(GTT2) "viable,fertile" FBgn0264707 RhoGEF3 Rho guanine nucleotide exchange factor 3 http://flybase.net/reports/FBgn0264707.html "FBgn0259743, FBgn0035128, FBgn0259724, FBgn0035127, FBgn0035126, FBgn0259744, FBan0013882, FBgn0259723, FBgn0035125" protein_coding_gene "0005089=Rho guanyl-nucleotide exchange factor activity, 0004871=signal transducer activity" "0035011=melanotic encapsulation of foreign target, 0035023=regulation of Rho protein signal transduction" "CG13881, CG13882, DrhoGEF3, RhoGEF3, CG42378, CG42377, CG43976, CG13883, rhoGEF3, RhoGEF, CG1225" "IPR001452=SH3 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000219=Dbl homology (DH) domain" CG43976 16-Dec-15 2015_12 "ENSMUSG00000037509,ENSMUSG00000021990(Spata13),ENSMUSG00000025656(Arhgef9)" FBgn0262595 CheA56a Chemosensory protein A 56a http://flybase.net/reports/FBgn0262595.html "FBgn0067315, FBgn0053724" protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CheA56a, CG33724" CG33724 16-Dec-15 2015_12 FBgn0262076 JC14 http://flybase.net/reports/FBgn0262076.html gene 0072347=response to anesthetic 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0035402 Usp5 Ubiquitin specific protease 5 http://flybase.net/reports/FBgn0035402.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 1990380=Lys48-specific deubiquitinase activity, 0008270=zinc ion binding, 0008242=omega peptidase activity" "0046329=negative regulation of JNK cascade, 0048812=neuron projection morphogenesis, 0043066=negative regulation of apoptotic process, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0071108=protein K48-linked deubiquitination, 0090364=regulation of proteasome assembly, 0001751=compound eye photoreceptor cell differentiation, 0010993=regulation of ubiquitin homeostasis, 0016579=protein deubiquitination, 0010995=free ubiquitin chain depolymerization" "0005737=cytoplasm, 0005634=nucleus" "CG12082, USP5, leon, Q9VZU7, DmUsp5, Isopeptidase T, isopeptidase T, usp5" "IPR015940=Ubiquitin-associated domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR018200=Ubiquitin specific protease, conserved site, IPR009060=UBA-like, IPR016652=Ubiquitinyl hydrolase, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain, IPR001607=Zinc finger, UBP-type" CG12082 16-Dec-15 2015_12 "ENSDARG00000014517(usp5),ENSDARG00000070820(LOC100332701)" YBR058C(UBP14) WBGene00020839(T27A3.2) ENSXETG00000023925(USP5) "ENSMUSG00000038429(Usp5),ENSMUSG00000056900(Usp13)" "ENSG00000111667(USP5),ENSG00000058056(USP13)" "lethal - all die before end of pupal stage,some die during pupal stage,locomotor behavior defective,short lived,visible" "wing,wing margin bristle,scutellar bristle" FBgn0040697 Teh3 tipE homolog 3 http://flybase.net/reports/FBgn0040697.html protein_coding_gene 0017080=sodium channel regulator activity 0002028=regulation of sodium ion transport 0016021=integral component of membrane "CG18676, TEH3" CG18676 16-Dec-15 2015_12 viable FBgn0030549 CG18637 http://flybase.net/reports/FBgn0030549.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065487 l(2)SH1259 lethal (2) SH1259 http://flybase.net/reports/FBgn0065487.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013501 l(1)PB18 lethal (1) PB18 http://flybase.net/reports/FBgn0013501.html gene 16-Dec-15 2015_12 "lethal,germline clone,recessive,rescuable maternal effect" "dorsal closure embryo,germline clone" FBgn0040051 CG17402 http://flybase.net/reports/FBgn0040051.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032242 CG5355 http://flybase.net/reports/FBgn0032242.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0070008=serine-type exopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "IPR002470=Peptidase S9A, prolyl oligopeptidase, IPR002471=Peptidase S9, serine active site, IPR023302=Peptidase S9A, N-terminal domain, IPR029058=Alpha/Beta hydrolase fold, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain" CG5355 16-Dec-15 2015_12 ENSDARG00000057151(prep) WBGene00001058(dpf-5) ENSXETG00000013305(prep) ENSMUSG00000019849(Prep) ENSG00000085377(PREP) viable FBgn0027934 ë±-Est4aë¬ ë±-Est4aë¬ http://flybase.net/reports/FBgn0027934.html "FBgn0020769, FBgn0051511" pseudogene_attribute "alphaE4, CR31511, DmalphaE4a-Psi, alphaE4a-Psi, alpha-EstPsi, alphaEsterase 4a-Psi, alphaEPsi, aE4a" CR31511 16-Dec-15 2015_12 DRSC12473 E 0.229846143 0.549824274 1.601292715 0.556970792 0.125857508 -0.35404361 FBgn0014192 hrp hyperpolarizing receptor potential http://flybase.net/reports/FBgn0014192.html gene 16-Dec-15 2015_12 "visual behavior defective,recessive,neurophysiology defective" retina FBgn0038567 CG14316 http://flybase.net/reports/FBgn0038567.html protein_coding_gene CG14316 16-Dec-15 2015_12 viable FBgn0086251 del deadlock http://flybase.net/reports/FBgn0086251.html "FBgn0032920, FBgn0000429" protein_coding_gene "0043148=mitotic spindle stabilization, 0030717=karyosome formation, 0007293=germarium-derived egg chamber formation, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0048477=oogenesis, 0045478=fusome organization, 0034587=piRNA metabolic process, 0048599=oocyte development" "0005634=nucleus, 0005813=centrosome" "deadlock, Deadlock, CG9252, Del" CG9252 16-Dec-15 2015_12 FBgn0035873 CG13670 http://flybase.net/reports/FBgn0035873.html protein_coding_gene 0008010=structural constituent of chitin-based larval cuticle 0040003=chitin-based cuticle development 0031012=extracellular matrix "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG13670 16-Dec-15 2015_12 viable FBgn0028539 CG31731 http://flybase.net/reports/FBgn0028539.html "FBgn0027851, FBgn0032532, FBgn0051731" protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006810=transport "0005886=plasma membrane, 0043190=ATP-binding cassette (ABC) transporter complex" "BG:DS00797.5, CG7559, DS00797.5, CG7491, D00797.5" "IPR026082=ABC transporter A, ABCA, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG31731 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0259975 Sfp87B Seminal fluid protein 87B http://flybase.net/reports/FBgn0259975.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "CG42485, GH21617p, Seminal fluid protein 87B" CG42485 16-Dec-15 2015_12 FBgn0033926 Arc1 Activity-regulated cytoskeleton associated protein 1 http://flybase.net/reports/FBgn0033926.html "FBgn0045908, FBgn0045910, FBgn0045912, FBgn0045913, FBgn0045923" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "0003012=muscle system process, 0042595=behavioral response to starvation" "0045202=synapse, 0030017=sarcomere" "Arc1, anon-WO0153538.40, anon-WO0153538.31, dARC1, anon-WO0153538.43, anon-WO0153538.45, CG12505, anon-WO0153538.41, Activity-regulated cytoskeleton associated protein 1, Arc, dArc1" "IPR001878=Zinc finger, CCHC-type" CG12505 16-Dec-15 2015_12 "viable,stress response defective,locomotor behavior defective" DRSC06159 IE -1.510182251 -4.046908545 -1.868193057 -1.047997169 -0.312952371 -0.219528614 FBgn0027639 mei-T3 mei-T3 http://flybase.net/reports/FBgn0027639.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "female sterile,recessive,meiotic cell cycle defective,female" FBgn0004444 prd11 paired-like 11 http://flybase.net/reports/FBgn0004444.html gene PRD gene 11 16-Dec-15 2015_12 " embryonic stage | <8-12 hr , oogenesis stage " FBgn0040101 lectin-24Fa lectin-24Fa http://flybase.net/reports/FBgn0040101.html gene 0005534=galactose binding "AC 004373A, AC004373a" 16-Dec-15 2015_12 FBgn0250904 CG34434 http://flybase.net/reports/FBgn0250904.html "FBgn0085463, FBan0015780, FBgn0029776, FBgn0029777" protein_coding_gene "CG17763, CG15780" CG34434 16-Dec-15 2015_12 FBgn0001128 Gpdh Glycerol 3 phosphate dehydrogenase http://flybase.net/reports/FBgn0001128.html protein_coding_gene "0042803=protein homodimerization activity, 0051287=NAD binding, 0004367=glycerol-3-phosphate dehydrogenase [NAD+] activity" "0007629=flight behavior, 0055114=oxidation-reduction process, 0046168=glycerol-3-phosphate catabolic process, 0005975=carbohydrate metabolic process, 0006641=triglyceride metabolic process, 0006072=glycerol-3-phosphate metabolic process, 0006127=glycerophosphate shuttle" "0031430=M band, 0005737=cytoplasm, 0030018=Z disc, 0009331=glycerol-3-phosphate dehydrogenase complex, 0005811=lipid particle" "CG9042, GPDH-1, Gdh, glycerol-3-phosphate dehydrogenase, sn-glycerol-3-phosphate, GPDA, alpha-Gpdh, alpha glycerophosphate dehydrogenase, alpha-GPDH, alphaGpdh-1, DmG3PDH, GPDH, 5' gene, G3PDH, alphaGPDH, gpdh, Glycerol-3-phosphate dehydrogenase, alphaGpdh, alpha-GPD, G3pdh, alphaGpd, Alpha-Glycerophosphate dehydrogenase, DROGPDHA, dehydrogenase, alpha-glycerophosphate dehydrogenase, alpha-GPDH-1, sn-glycerol 3-phosphate dehydrogenase, Gpd, sn-glycerol-3-phosphate dehydrogenase, alpha-glycerol phosphate dehydrogenase, sn-Gpdh, GPD, glycerophosphate dehydrogenase, alpha-glycerol-3-phosphate dehydrogenase, GAPDH, gpdh-1" "IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011128=Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal, IPR006168=Glycerol-3-phosphate dehydrogenase, NAD-dependent, IPR017751=Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic, IPR016040=NAD(P)-binding domain, IPR006109=Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal, IPR013328=6-phosphogluconate dehydrogenase, domain 2" CG9042 16-Dec-15 2015_12 "ENSDARG00000043180(gpd1b),ENSDARG00000043701(gpd1a),ENSDARG00000040024(gpd1l),ENSDARG00000036942(gpd1)" "YDL022W(GPD1),YOL059W(GPD2)" WBGene00010778(gpdh-2) "ENSXETG00000013352(gpd1),ENSXETG00000015022(gpd1l)" "ENSMUSG00000023019(Gpd1),ENSMUSG00000050627(Gpd1l)" "ENSG00000167588(GPD1),ENSG00000152642(GPD1L)" " larval stage && adult stage , adult stage " "electrophoretic variant,viable,reduced,fertile,fast,lethal,recessive,flightless,flight defective,dominant,short lived,slow" embryonic/larval hemocyte | third instar larval stage FBgn0264283 Su(Mir)2E2-3 http://flybase.net/reports/FBgn0264283.html gene 16-Dec-15 2015_12 lethal FBgn0267227 CR45667 http://flybase.net/reports/FBgn0267227.html non_protein_coding_gene CR45667 16-Dec-15 2015_12 FBgn0043566 Su(hh)I Su(hh)I http://flybase.net/reports/FBgn0043566.html gene 16-Dec-15 2015_12 FBgn0019799 l(1)06 lethal (1) 06 http://flybase.net/reports/FBgn0019799.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003631 Su(var)325 Suppressor of variegation 325 http://flybase.net/reports/FBgn0003631.html gene 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant" FBgn0037529 mRpS9 mitochondrial ribosomal protein S9 http://flybase.net/reports/FBgn0037529.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005763=mitochondrial small ribosomal subunit, 0005739=mitochondrion" "MRP-S9, CG2957" "IPR000754=Ribosomal protein S9, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568=Ribosomal protein S5 domain 2-type fold" CG2957 16-Dec-15 2015_12 ENSDARG00000061505(zgc:153172) WBGene00017319(F09G8.3) ENSXETG00000002583(MRPS9) ENSMUSG00000060679(Mrps9) ENSG00000135972(MRPS9) "viable,visible" trichogen cell DRSC15456 K -0.26411989 -0.377855405 0.057366662 0.109386816 1.768465959 -1.366362362 FBgn0043488 fs(3)66EFb fs(3)66EFb http://flybase.net/reports/FBgn0043488.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0060529 l(3)S101504 lethal (3) S101504 http://flybase.net/reports/FBgn0060529.html gene 1015/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0060590 l(3)S093501b lethal (3) S093501b http://flybase.net/reports/FBgn0060590.html gene "l(3)s093501, 0935/01" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0064182 h::brk h::brk http://flybase.net/reports/FBgn0064182.html engineered_fusion_gene 16-Dec-15 2015_12 "viable,female,lethal" FBgn0024726 Su(var)13T Su(var)13T http://flybase.net/reports/FBgn0024726.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant" FBgn0086542 MRE10 mRNA-like ncRNA in embryogenesis 10 http://flybase.net/reports/FBgn0086542.html non_protein_coding_gene GM08676 16-Dec-15 2015_12 FBgn0053927 CG33927 http://flybase.net/reports/FBgn0053927.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33927 16-Dec-15 2015_12 FBgn0022174 l(2)k05420 lethal (2) k05420 http://flybase.net/reports/FBgn0022174.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040572 CG17201 http://flybase.net/reports/FBgn0040572.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065208 l(2)SH2271 lethal (2) SH2271 http://flybase.net/reports/FBgn0065208.html gene l(2)SH2 2271 16-Dec-15 2015_12 "lethal,recessive" FBgn0002556 lme lame http://flybase.net/reports/FBgn0002556.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment,wing" FBgn0067644 sunny-side-up sunny side up http://flybase.net/reports/FBgn0067644.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0026743 anon-45Aa anon-45Aa http://flybase.net/reports/FBgn0026743.html gene CLOT3064 16-Dec-15 2015_12 FBgn0032178 Spn31A Serpin 31A http://flybase.net/reports/FBgn0032178.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005615=extracellular space CG4804 "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG4804 16-Dec-15 2015_12 viable FBgn0267048 CG45492 http://flybase.net/reports/FBgn0267048.html protein_coding_gene CG45492 16-Dec-15 2015_12 FBgn0259361 EP-709 http://flybase.net/reports/FBgn0259361.html gene 16-Dec-15 2015_12 visible wing vein FBgn0004033 xwh extra wing hairs http://flybase.net/reports/FBgn0004033.html gene 16-Dec-15 2015_12 FBgn0027999 l(3)S121910b lethal (3) S121910b http://flybase.net/reports/FBgn0027999.html gene "l(3)S121910, 1219/10" 16-Dec-15 2015_12 "lethal,recessive" FBgn0001679 l(1)ER lethal (1) ER http://flybase.net/reports/FBgn0001679.html gene l(1)ER[ts] 16-Dec-15 2015_12 "lethal,heat sensitive" "nucleus | embryonic stage,yolk" FBgn0053626 CG33626 http://flybase.net/reports/FBgn0053626.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33626 16-Dec-15 2015_12 FBgn0264433 CG43851 http://flybase.net/reports/FBgn0264433.html protein_coding_gene "IPR008978=HSP20-like chaperone, IPR002068=Alpha crystallin/Hsp20 domain" CG43851 16-Dec-15 2015_12 FBgn0034059 CG8320 http://flybase.net/reports/FBgn0034059.html protein_coding_gene "IPR008506=Protein of unknown function DUF788, TMEM208" CG8320 16-Dec-15 2015_12 "ENSDARG00000032040,ENSDARG00000068291(zgc:77041)" WBGene00011033(R05D11.5) ENSMUSG00000014856(Tmem208) ENSG00000168701(TMEM208) FBgn0000030 AcpC Accessory gland protein C http://flybase.net/reports/FBgn0000030.html gene 16-Dec-15 2015_12 electrophoretic variant FBgn0052668 CG32668 http://flybase.net/reports/FBgn0052668.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG32668 16-Dec-15 2015_12 ENSDARG00000022660(armc2) ENSXETG00000021284() ENSMUSG00000071324(Armc2) ENSG00000118690(ARMC2) viable FBgn0267141 CR45581 http://flybase.net/reports/FBgn0267141.html non_protein_coding_gene CR45581 16-Dec-15 2015_12 FBgn0062583 Mod(var)224 Mod(var)224 http://flybase.net/reports/FBgn0062583.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 224 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0023064 l(1)20Cc lethal (1) 20Cc http://flybase.net/reports/FBgn0023064.html gene C2/5.5 16-Dec-15 2015_12 "lethal,recessive" FBgn0016833 l(1)MZ20 lethal (1) MZ20 http://flybase.net/reports/FBgn0016833.html gene M20 16-Dec-15 2015_12 "lethal,recessive" FBgn0014971 l(1)13Fa lethal (1) 13Fa http://flybase.net/reports/FBgn0014971.html gene "V, l(1)V" 16-Dec-15 2015_12 "lethal,recessive" FBgn0000920 fs(1)ne7 female sterile (1) no eggs 7 http://flybase.net/reports/FBgn0000920.html gene "ne7, fs(1)ne[7]" 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,chorion,oocyte" FBgn0025366 Ip259 Intronic Protein 259 http://flybase.net/reports/FBgn0025366.html FBgn0064114 protein_coding_gene "0006909=phagocytosis, 0022008=neurogenesis" "IP259, CG5277" IPR022309=Ribosomal protein S8e/ribosomal biogenesis NSA2 CG5277 16-Dec-15 2015_12 ENSDARG00000007708(nsa2) YER126C(NSA2) WBGene00012351(W09C5.1) ENSXETG00000005077(tinp1) ENSMUSG00000060739(Nsa2) ENSG00000164346(NSA2) "lethal,recessive,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC03352 E -0.682671689 -0.815977117 1.63757639 -1.744638167 -0.505634386 0.046446407 FBgn0085693 CG41562 http://flybase.net/reports/FBgn0085693.html FBan0041562 protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG41562 16-Dec-15 2015_12 ENSDARG00000043666(zgc:109995) YNR054C(ESF2) WBGene00019005(F57B10.8) ENSXETG00000005684(ABT1) ENSMUSG00000036376(Abt1) ENSG00000146109(ABT1) FBgn0028327 l(1)G0320 lethal (1) G0320 http://flybase.net/reports/FBgn0028327.html "FBgn0030135, FBgn0052701" protein_coding_gene 0005048=signal sequence binding "0012505=endomembrane system, 0005811=lipid particle, 0045169=fusome, 0005783=endoplasmic reticulum, 0005785=signal recognition particle receptor complex" "CG2994, CG32701" "IPR005595=Translocon-associated protein (TRAP), alpha subunit" CG32701 16-Dec-15 2015_12 ENSDARG00000040518(ssr1) WBGene00022122(trap-1) ENSXETG00000020431(ssr1) ENSMUSG00000021427(Ssr1) ENSG00000124783(SSR1) "viable,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0004821 fs(2)ltoRM7 female sterile (2) ltoRM7 http://flybase.net/reports/FBgn0004821.html gene 0007300=ovarian nurse cell to oocyte transport 16-Dec-15 2015_12 female sterile FBgn0051440 CG31440 http://flybase.net/reports/FBgn0051440.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267491 Mst77Y-13 Male-specific transcript 77Y 13 http://flybase.net/reports/FBgn0267491.html "FBgn0262762, FBgn0267414" protein_coding_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin CG45767 CG45767 16-Dec-15 2015_12 FBgn0039808 CG12071 http://flybase.net/reports/FBgn0039808.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" 0006909=phagocytosis "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG12071 16-Dec-15 2015_12 YGL035C(MIG1) FBgn0026386 Or47a Odorant receptor 47a http://flybase.net/reports/FBgn0026386.html protein_coding_gene "0005549=odorant binding, 0004888=transmembrane signaling receptor activity, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "47E.1, Or24, dor24, Olfactory receptor 47E.1, or47a, DOR47E.1, DOR24, OR47a, CG13225, Or47E.1, AN10, 47a" "IPR004117=Olfactory receptor, Drosophila" CG13225 16-Dec-15 2015_12 "neurophysiology defective,smell perception defective" large sensillum basiconicum of antennal segment 3 & olfactory neuronOr22a.8197 FBgn0264843 CR44051 http://flybase.net/reports/FBgn0264843.html non_protein_coding_gene CR44051 16-Dec-15 2015_12 FBgn0034938 CG3803 http://flybase.net/reports/FBgn0034938.html protein_coding_gene "0016627=oxidoreductase activity, acting on the CH-CH group of donors" "0006784=heme a biosynthetic process, 0055114=oxidation-reduction process, 0008535=respiratory chain complex IV assembly" "0016021=integral component of membrane, 0005743=mitochondrial inner membrane" "IPR009003=Peptidase S1, PA clan, IPR003780=COX15/CtaA family" CG3803 16-Dec-15 2015_12 ENSDARG00000011626(LOC100331376) YER141W(COX15) WBGene00011526(T06D8.5) ENSXETG00000003745(COX15) ENSMUSG00000040018(Cox15) ENSG00000014919(COX15) viable FBgn0024656 l(2)k07822 lethal (2) k07822 http://flybase.net/reports/FBgn0024656.html gene 78/22 16-Dec-15 2015_12 "visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing,wing vein" FBgn0004980 Bubble Bubble http://flybase.net/reports/FBgn0004980.html gene "Balloon, Bb" 16-Dec-15 2015_12 "visible,dominant,male sterile" wing FBgn0086252 M(2)56i Minute (2) 56i http://flybase.net/reports/FBgn0086252.html gene Minute(2)56i 16-Dec-15 2015_12 FBgn0004150 l(2)57Ad lethal (2) 57Ad http://flybase.net/reports/FBgn0004150.html gene 16-Dec-15 2015_12 lethal FBgn0034963 Not11 http://flybase.net/reports/FBgn0034963.html protein_coding_gene "0017148=negative regulation of translation, 0006402=mRNA catabolic process" 0030014=CCR4-NOT complex "C2orf29, NOT11, CG13567" IPR019312=Protein of unknown function DUF2363 CG13567 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0023157 Su(mg)2-2 Suppressor of modifier of gypsy 2-2 http://flybase.net/reports/FBgn0023157.html gene 16-Dec-15 2015_12 "visible,recessive" "eye,macrochaeta" FBgn0026651 l(2)46F4 lethal (2) 46F4 http://flybase.net/reports/FBgn0026651.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0034785 CG3649 http://flybase.net/reports/FBgn0034785.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG3649 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" viable FBgn0004591 Eig71Ed Ecdysone-induced gene 71Ed http://flybase.net/reports/FBgn0004591.html FBgn0063120 protein_coding_gene "0042742=defense response to bacterium, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death" 0005576=extracellular region "BcDNA:LP04160, CG7350, gene-IV, L71, L71-4, 71E-Gene-IV, Eig 71Ed, gene IV, Gene IV, IV" IPR003475=Insect protein of unknown function CG7350 16-Dec-15 2015_12 viable FBgn0052026 CG32026 http://flybase.net/reports/FBgn0052026.html "FBgn0044671, FBgn0047312" protein_coding_gene "0051287=NAD binding, 0004449=isocitrate dehydrogenase (NAD+) activity, 0000287=magnesium ion binding" 0055114=oxidation-reduction process "0005875=microtubule associated complex, 0005962=mitochondrial isocitrate dehydrogenase complex (NAD+)" "BcDNA:GH12815, anon-WO0140519.202" "IPR019818=Isocitrate/isopropylmalate dehydrogenase, conserved site, IPR024084=Isopropylmalate dehydrogenase-like domain, IPR001804=Isocitrate and isopropylmalate dehydrogenases family" CG32026 16-Dec-15 2015_12 YOR136W(IDH2) viable FBgn0014173 fs(3)96A-96B fs(3)96A-96B http://flybase.net/reports/FBgn0014173.html gene unnamed 16-Dec-15 2015_12 female semi-sterile FBgn0259613 B0699 http://flybase.net/reports/FBgn0259613.html gene 16-Dec-15 2015_12 visible "leg,unguis,tarsal segment,antennal segment,arista" FBgn0036716 CG13728 http://flybase.net/reports/FBgn0036716.html protein_coding_gene CG13728 16-Dec-15 2015_12 viable FBgn0010069 M(3)bb Minute (3) bb http://flybase.net/reports/FBgn0010069.html gene M(3)[bb] 16-Dec-15 2015_12 "Minute,visible" macrochaeta FBgn0035426 CG12078 http://flybase.net/reports/FBgn0035426.html protein_coding_gene 0004722=protein serine/threonine phosphatase activity "0006470=protein dephosphorylation, 0048812=neuron projection morphogenesis" 0005737=cytoplasm 24656659 "IPR004274=FCP1 homology domain, IPR011948=Dullard phosphatase domain, eukaryotic, IPR023214=HAD-like domain" CG12078 16-Dec-15 2015_12 viable FBgn0261455 scaRNA:MeU5-G38 small Cajal body-specific RNA : MeU5-G38 http://flybase.net/reports/FBgn0261455.html snoRNA_gene 0015030=Cajal body "mgU5-38, scaRNA:mgU5-38, scaRNA:pit-a" CR43572 16-Dec-15 2015_12 FBgn0039338 XNP XNP http://flybase.net/reports/FBgn0039338.html FBgn0062645 protein_coding_gene "0016887=ATPase activity, 0003678=DNA helicase activity, 0005524=ATP binding" "0097193=intrinsic apoptotic signaling pathway, 0006351=transcription, DNA-templated, 0008347=glial cell migration, 0046328=regulation of JNK cascade, 0051276=chromosome organization, 0007399=nervous system development, 0070868=heterochromatin organization involved in chromatin silencing, 0007411=axon guidance, 0006336=DNA replication-independent nucleosome assembly" "0005722=beta-heterochromatin, 0042585=germinal vesicle, 0005634=nucleus, 0000775=chromosome, centromeric region, 0005700=polytene chromosome" "dXNP, xnp/atr-x, ATR-X/XNP, EP(3)0635, DATRX, EP635, xnp, dATRX, DATR-X, CG4548" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain" CG4548 16-Dec-15 2015_12 ENSDARG00000057901(LOC100331173) WBGene00006961(xnp-1) "neuroanatomy defective,viable,fertile,suppressor of variegation,dominant,partially lethal - majority die,recessive,visible,lethal" "longitudinal connective,interface glial cell,embryonic/larval glial cell,Kenyon cell,adult mushroom body,scutellum,adult thorax,microchaeta,anterior commissure,posterior commissure" FBgn0027943 pru perugino http://flybase.net/reports/FBgn0027943.html gene 16-Dec-15 2015_12 FBgn0040958 Peritrophin-15b Peritrophin-15b http://flybase.net/reports/FBgn0040958.html FBgn0051893 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process "0005576=extracellular region, 0005615=extracellular space" "Dm-peritrophin-15b, CG31893, Dm15b, CG13395, Peritrophi-15b" IPR002557=Chitin binding domain CG31893 16-Dec-15 2015_12 viable FBgn0250843 Prosë±6 Proteasome ë±6 subunit http://flybase.net/reports/FBgn0250843.html "FBgn0003151, FBgn0066882" protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0006511=ubiquitin-dependent protein catabolic process, 0007370=ventral furrow formation, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005737=cytoplasm, 0005634=nucleus, 0000502=proteasome complex, 0005875=microtubule associated complex, 0019773=proteasome core complex, alpha-subunit complex" "Alpha-6, PROS-35, pros 35, 20S proteasome, CG4904, 143314_at, pros35, 20S alpha6 subunit, 20s proteasome, alpha-subunit of 20S proteasome, Proteasome 35kDa subunit, Proteasome 35, Proteasome 35kD subunit, Proteasome 35 kD subunit, unnamed, alpha-6, Pros35, PROS-Dm35, anon-SAGE:Wang-116, alpha_dm, Pros-35, Proteasome 35-kDa subunit, Pros-Dm35, Prosalpha6, alpha6, PSMA1" "IPR023332=Proteasome A-type subunit, IPR001353=Proteasome, subunit alpha/beta, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR029055=Nucleophile aminohydrolases, N-terminal" CG4904 16-Dec-15 2015_12 ENSDARG00000026900 YMR314W(PRE5) WBGene00003927(pas-6) ENSXETG00000019680(PSMA1) ENSMUSG00000030751(Psma1) ENSG00000129084(PSMA1) DRSC03401 IE -2.2742969 -2.664140861 -1.395674873 -2.40272079 -0.36722362 0.839614359 FBgn0003268 rod rough deal http://flybase.net/reports/FBgn0003268.html FBgn0044458 protein_coding_gene 0005515=protein binding "0007094=mitotic spindle assembly checkpoint, 0034501=protein localization to kinetochore, 0007030=Golgi organization, 0030071=regulation of mitotic metaphase/anaphase transition, 0000070=mitotic sister chromatid segregation" "0036063=acroblast, 0051233=spindle midzone, 0005737=cytoplasm, 0000776=kinetochore, 0005795=Golgi stack, 0005819=spindle, 1990423=RZZ complex, 0005828=kinetochore microtubule, 0000940=condensed chromosome outer kinetochore" "pNB20A, roughdeal, CG1569, EP3408, Rod, Rough deal, Rough Deal, ROD, unnamed" "IPR019527=RZZ complex, subunit KNTC1/ROD, C-terminal" CG1569 16-Dec-15 2015_12 WBGene00018900(rod-1) ENSMUSG00000029414(Kntc1) ENSG00000184445(KNTC1) " larval stage | third instar , larval stage , spermatogenesis && adult stage " " neuroblast &&of larval brain

, larval brain

, spermatocyte

" "visible,viable,fertile,lethal - all die before end of larval stage,recessive,some die during larval stage,reduced,mitotic cell cycle defective,wild-type,lethal,partially lethal - majority live" "eye,intersegmental nerve,nuclear chromosome & mitotic anaphase,chromatin & mitotic anaphase,chromatin & mitotic telophase,mitotic anaphase,Golgi stack,acroblast,spermatocyte,meiotic cell cycle,neuroblast,nuclear chromosome,trichogen cell" FBgn0083115 W36 W36 http://flybase.net/reports/FBgn0083115.html gene 16-Dec-15 2015_12 "viable,visible" "wing,wing vein L5" FBgn0028423 JhI-4 JhI-4 http://flybase.net/reports/FBgn0028423.html gene unnamed 16-Dec-15 2015_12 FBgn0005539 l(3)72Dg lethal (3) 72Dg http://flybase.net/reports/FBgn0005539.html gene 16-Dec-15 2015_12 lethal FBgn0015497 l(3)65CEa lethal (3) 65CEa http://flybase.net/reports/FBgn0015497.html gene "X, Distal W5.4 Group X" 16-Dec-15 2015_12 lethal FBgn0260374 GSd034 http://flybase.net/reports/FBgn0260374.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,segmental nerve,intersegmental nerve" FBgn0013670 ms(3)neo79 ms(3)neo79 http://flybase.net/reports/FBgn0013670.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0038202 CG12402 http://flybase.net/reports/FBgn0038202.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXL11 "IPR006553=Leucine-rich repeat, cysteine-containing subtype, IPR001810=F-box domain" CG12402 16-Dec-15 2015_12 ENSDARG00000046010 WBGene00007206(B0564.6) viable FBgn0002352 l(3)87Dd lethal (3) 87Dd http://flybase.net/reports/FBgn0002352.html gene "m14, mes14, l(3)m14" 16-Dec-15 2015_12 lethal FBgn0044025 PK19 Pocket 19 http://flybase.net/reports/FBgn0044025.html gene 0050909=sensory perception of taste 16-Dec-15 2015_12 FBgn0010746 l(3)01374 lethal (3) 01374 http://flybase.net/reports/FBgn0010746.html gene l(3)01373 16-Dec-15 2015_12 partially lethal - majority die FBgn0024604 olfS20 olfactory S20 http://flybase.net/reports/FBgn0024604.html gene 16-Dec-15 2015_12 smell perception defective FBgn0000691 flrdO flight reduced O http://flybase.net/reports/FBgn0000691.html gene 16-Dec-15 2015_12 flight defective FBgn0004968 juv juvenile http://flybase.net/reports/FBgn0004968.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal" "dorsal appendage,ovary" FBgn0042125 CG18787 http://flybase.net/reports/FBgn0042125.html protein_coding_gene 0046872=metal ion binding "IPR000571=Zinc finger, CCCH-type" CG18787 16-Dec-15 2015_12 ENSXETG00000005935(nupl2) ENSG00000136243(NUPL2) FBgn0031670 CG3887 http://flybase.net/reports/FBgn0031670.html protein_coding_gene 0008430=selenium binding 0045454=cell redox homeostasis 0012505=endomembrane system "IPR012336=Thioredoxin-like fold, IPR019389=Selenoprotein T, IPR011893=Selenoprotein, Rdx type" CG3887 16-Dec-15 2015_12 "ENSDARG00000023220(selt2),ENSDARG00000027595(selt1b),ENSDARG00000058354(selt1a)" "WBGene00007955(C35C5.3),WBGene00009238(F28H7.4)" ENSXETG00000020094(BC059764.1) ENSMUSG00000075700(2810407C02Rik) ENSG00000198843(SELT) FBgn0040032 CG17626 http://flybase.net/reports/FBgn0040032.html FBan0017626 protein_coding_gene 16-Dec-15 2015_12 FBgn0263907 l(3)GL29 http://flybase.net/reports/FBgn0263907.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0069200 l(2)DJ690 lethal (2) DJ690 http://flybase.net/reports/FBgn0069200.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043905 bns bird's nest soup http://flybase.net/reports/FBgn0043905.html gene "0007110=meiosis I cytokinesis, 0007111=meiosis II cytokinesis" "span, Separation anxiety, separation anxiety, San" 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,cytokinesis defective" "contractile ring & meiotic telophase I | male,contractile ring & meiotic telophase II | male" FBgn0031941 ATPsynGL "ATP synthase, subunit G-like" http://flybase.net/reports/FBgn0031941.html protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" 0015986=ATP synthesis coupled proton transport "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), 0005753=mitochondrial proton-transporting ATP synthase complex" "ATP synthase g chain, ATP synthase G chain, CG7211, ATPN" "IPR006808=ATPase, F0 complex, subunit G, mitochondrial, IPR016702=Mitochondrial ATP synthase subunit g, animal" CG7211 16-Dec-15 2015_12 ENSDARG00000011841(atp5l) "WBGene00000210(asg-2),WBGene00000209(asg-1)" ENSXETG00000010111() viable FBgn0263047 CG43342 http://flybase.net/reports/FBgn0263047.html "FBgn0038954, FBgn0038955, FBgn0045280, FBgn0045289, FBan0031169, FBgn0051169" protein_coding_gene "0003677=DNA binding, 0004367=glycerol-3-phosphate dehydrogenase [NAD+] activity" "0006072=glycerol-3-phosphate metabolic process, 0055114=oxidation-reduction process" 0009331=glycerol-3-phosphate dehydrogenase complex "CG12757, CG31169, gpdh-3" "IPR004210=BESS motif, IPR006168=Glycerol-3-phosphate dehydrogenase, NAD-dependent" CG43342 16-Dec-15 2015_12 FBgn0041340 Circe\pol pol http://flybase.net/reports/FBgn0041340.html transposable_element_gene "ORF2b, ORF2a" 16-Dec-15 2015_12 FBgn0032030 Wdr82 WD repeat domain 82 http://flybase.net/reports/FBgn0032030.html protein_coding_gene "0051568=histone H3-K4 methylation, 0080182=histone H3-K4 trimethylation, 0051013=microtubule severing" "0048188=Set1C/COMPASS complex, 0008352=katanin complex, 0035097=histone methyltransferase complex" "wdr82, WDR82, wdr-82, CG17293, dWdr82" "IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG17293 16-Dec-15 2015_12 ENSDARG00000014083(twf2) YKL018W(SWD2) WBGene00016374(swd-2.2) ENSXETG00000002763(TEgg072c23.1) ENSMUSG00000020257(Wdr82) ENSG00000164091(WDR82) "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,female fertile,fertile" mesothoracic tergum DRSC21723 IEK -3.371119501 -0.852577524 -2.524583738 -3.867727441 0.980847832 1.599820079 FBgn0016632 E(gl)2H Enhancer of glass 2H http://flybase.net/reports/FBgn0016632.html gene 16-Dec-15 2015_12 FBgn0017424 CR11538 http://flybase.net/reports/FBgn0017424.html FBgn0036252 non_protein_coding_gene 0005616=larval serum protein complex "anon-68Ed, CG11538, unnamed" CR11538 16-Dec-15 2015_12 FBgn0002316 l(3)85Ag lethal (3) 85Ag http://flybase.net/reports/FBgn0002316.html gene L7 16-Dec-15 2015_12 lethal FBgn0028536 CG15281 http://flybase.net/reports/FBgn0028536.html "FBgn0032548, FBgn0042191, FBgn0062917" protein_coding_gene "BcDNA:RH63170, BG:DS00810.3, DS00810.3, CG18456" 16-Dec-15 2015_12 DRSC02482 K -0.300874438 -0.111137015 -0.217710967 0.289698543 2.397028617 -0.985338632 FBgn0052287 tRNA:CR32287 transfer RNA:CR32287 http://flybase.net/reports/FBgn0052287.html FBgn0060268 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:C:GCA:AE002584-e, AE002584.trna16-CysGCA, chr3L.trna16-CysGCA, CR32287" CR32287 16-Dec-15 2015_12 FBgn0265642 CR44449 http://flybase.net/reports/FBgn0265642.html non_protein_coding_gene lincRNA.267 CR44449 16-Dec-15 2015_12 FBgn0010624 l(2)06708 lethal (2) 06708 http://flybase.net/reports/FBgn0010624.html gene 16-Dec-15 2015_12 FBgn0038973 Pebp1 Phosphatidylethanolamine-binding protein 1 http://flybase.net/reports/FBgn0038973.html FBgn0063081 protein_coding_gene "0002759=regulation of antimicrobial humoral response, 0050830=defense response to Gram-positive bacterium, 0050829=defense response to Gram-negative bacterium" "PEBP1, T2, CG18594, BcDNA:LP12095" IPR008914=Phosphatidylethanolamine-binding protein PEBP CG18594 16-Dec-15 2015_12 "YLR179C(),YLR178C(TFS1)" "immune response defective,viable" FBgn0039797 CG1340 http://flybase.net/reports/FBgn0039797.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding, 0003743=translation initiation factor activity" 0006413=translational initiation 0005829=cytosol "cg1340, eIF4H" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG1340 16-Dec-15 2015_12 ENSXETG00000018230(wbscr1) ENSMUSG00000040731(Eif4h) ENSG00000106682(EIF4H) "visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0022387 Mpi Mannose phosphate isomerase http://flybase.net/reports/FBgn0022387.html gene MPI 16-Dec-15 2015_12 FBgn0036846 MESR6 Misexpression suppressor of ras 6 http://flybase.net/reports/FBgn0036846.html protein_coding_gene 0046580=negative regulation of Ras protein signal transduction "Misexpression Suppressor of Ras 6, CG6818" IPR024131=Uncharacterised protein family UPF0489 CG6818 16-Dec-15 2015_12 ENSDARG00000011723(zgc:56556) ENSXETG00000005865(TEgg058p12.1) ENSMUSG00000022195(6030458C11Rik) ENSG00000082213(C5orf22) "viable,fertile,partially lethal - majority die,wild-type" pupa FBgn0024613 olf345 olfactory 345 http://flybase.net/reports/FBgn0024613.html gene 16-Dec-15 2015_12 FBgn0065057 scaRNA:MeU2-C28 small Cajal body-specific RNA : MeU2-C28 http://flybase.net/reports/FBgn0065057.html FBgn0053726 snoRNA_gene "0030563=snRNA 2'-O-ribose methylation guide activity, 0030555=RNA modification guide activity" "0005730=nucleolus, 0015030=Cajal body" "mgU2-28, snoR700, CR33726, snoRNA:MeU2-C28, MeU2-C28(SnoR700), Dm-700, snoRNA:700" CR33726 16-Dec-15 2015_12 FBgn0041746 l(1)em3 lethal (1) em3 http://flybase.net/reports/FBgn0041746.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005615 fs(2)lto1 female sterile (2) lto1 http://flybase.net/reports/FBgn0005615.html "FBgn0000997, FBgn0004804, FBgn0004810" gene 0007304=chorion-containing eggshell formation "fs(2)PN48, PN48, fs(2)lo-D, fs(2)ltoPN48" 16-Dec-15 2015_12 female sterile FBgn0035308 CG15822 http://flybase.net/reports/FBgn0035308.html protein_coding_gene IPR001251=CRAL-TRIO lipid binding domain CG15822 16-Dec-15 2015_12 ENSDARG00000040614(sestd1) ENSMUSG00000042272(Sestd1) ENSG00000187231(SESTD1) DRSC08482 K 0.118071776 -1.352674248 -0.716369395 -0.272886829 1.706695304 -0.616214263 FBgn0030661 CG8105 http://flybase.net/reports/FBgn0030661.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface FBgn0030661 "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase, IPR017850=Alkaline-phosphatase-like, core domain" CG8105 16-Dec-15 2015_12 YDR481C(PHO8) viable FBgn0031119 CG1812 http://flybase.net/reports/FBgn0031119.html protein_coding_gene 0003779=actin binding "IPR015915=Kelch-type beta propeller, IPR011705=BTB/Kelch-associated, IPR006652=Kelch repeat type 1, IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR017096=BTB-kelch protein" CG1812 16-Dec-15 2015_12 viable FBgn0015022 Chap71 Chromosome-associated protein 71kD http://flybase.net/reports/FBgn0015022.html gene 0003682=chromatin binding unnamed 16-Dec-15 2015_12 FBgn0038570 Prx5 Peroxiredoxin 5 http://flybase.net/reports/FBgn0038570.html "FBgn0052920, FBtr0083620, FBpp0083040, FBtr0083621, FBpp0083041, FBtr0083622, FBpp0083042" protein_coding_gene "0008379=thioredoxin peroxidase activity, 0016209=antioxidant activity" "0045824=negative regulation of innate immune response, 0008340=determination of adult lifespan, 0045454=cell redox homeostasis, 0006979=response to oxidative stress, 0042744=hydrogen peroxide catabolic process, 0043066=negative regulation of apoptotic process" "0005739=mitochondrion, 0005829=cytosol, 0005634=nucleus, 0005777=peroxisome" "dPrx5, dPrxV, CG7217, CG 7217, CG 32920, peroxiredoxin 5, dprx5, CG32920, Peroxiredoxin V, prx5" "IPR013740=Redoxin, IPR012336=Thioredoxin-like fold" CG7217 16-Dec-15 2015_12 ENSDARG00000055064(prdx5) YLR109W(AHP1) ENSXETG00000006009(PRDX5) ENSMUSG00000024953(Prdx5) ENSG00000126432(PRDX5) "immune response defective,chemical sensitive,stress response defective,short lived,increased cell death,lethal - all die before end of embryonic stage,parental effect,some die during embryonic stage,long lived,chemical resistant" FBgn0022774 Oat Ornithine aminotransferase precursor http://flybase.net/reports/FBgn0022774.html FBgn0036898 protein_coding_gene "0030170=pyridoxal phosphate binding, 0004587=ornithine-oxo-acid transaminase activity" "0006591=ornithine metabolic process, 0022008=neurogenesis" "0005759=mitochondrial matrix, 0005739=mitochondrion" "CG8782, 151832_at, ornithine aminotransferase" "IPR015424=Pyridoxal phosphate-dependent transferase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR010164=Ornithine aminotransferase, IPR005814=Aminotransferase class-III" CG8782 16-Dec-15 2015_12 ENSDARG00000060203 YLR438W(CAR2) WBGene00015814(C16A3.10) ENSXETG00000009576(oat) ENSMUSG00000030934(Oat) ENSG00000065154(OAT) "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "ganglion mother cell,trichogen cell" FBgn0013565 l(3)78Aa lethal (3) 78Aa http://flybase.net/reports/FBgn0013565.html gene 16-Dec-15 2015_12 lethal FBgn0039052 CG6733 http://flybase.net/reports/FBgn0039052.html protein_coding_gene 0004046=aminoacylase activity 0006520=cellular amino acid metabolic process 0005737=cytoplasm "IPR011650=Peptidase M20, dimerisation domain, IPR002933=Peptidase M20, IPR010159=N-acyl-L-amino-acid amidohydrolase" CG6733 16-Dec-15 2015_12 "ENSDARG00000004845(LOC100001620),ENSDARG00000038475(zgc:55605)" "WBGene00007507(C10C5.3),WBGene00007508(C10C5.4),WBGene00007509(C10C5.5),WBGene00015509(C06A6.4)" ENSXETG00000000089(acy1) ENSMUSG00000023262(Acy1) ENSG00000114786(ACY1) viable FBgn0033309 CG8735 http://flybase.net/reports/FBgn0033309.html protein_coding_gene 0012505=endomembrane system Lunapark IPR019273=Lunapark domain CG8735 16-Dec-15 2015_12 "ENSDARG00000006639(lnpb),ENSDARG00000063646(lnpa)" WBGene00015492(lnp-1) ENSXETG00000007570(TEgg059c18.1) ENSMUSG00000009207(Lnp) ENSG00000144320(KIAA1715) "lethal,viable" embryonic/larval brain FBgn0034763 RYBP Ring and YY1 Binding Protein http://flybase.net/reports/FBgn0034763.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" "0043066=negative regulation of apoptotic process, 0050777=negative regulation of immune response, 0010623=developmental programmed cell death, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0016604=nuclear body "CG12190, dRYBP" "IPR001876=Zinc finger, RanBP2-type" CG12190 16-Dec-15 2015_12 "ENSDARG00000053459(rybpb),ENSDARG00000007850,ENSDARG00000015966(yaf2),ENSDARG00000037773(rybpa)" ENSXETG00000015914(rybp) "ENSMUSG00000022634(Yaf2),ENSMUSG00000072872(Rybp),ENSMUSG00000055763" "ENSG00000015153(YAF2),ENSG00000163602(RYBP)" "partially lethal - majority die,lethal,developmental rate defective,female sterile,visible,somatic clone,increased cell death,size defective,female fertile" "wing vein L5,distal,wing,leg,abdominal sternite 6,male,organism | embryonic stage,somatic clone,trichome & haltere | ectopicsd-SG29.1,wing hair,wing vein,triple row,scutellum,scutum,humerus,ectopic,trichome & haltere | ectopicen-e16E,wing vein L4,trichome of the posterior wing margin,sex comb,metathoracic leg,mesothoracic leg,adult abdominal segment 1,adult abdominal segment 4,wing disc | third instar larval stage,haltere disc | third instar larval stage,ventral thoracic disc | third instar larval stage,antennal disc | third instar larval stage,denticle belt,wing disc,haltere trichome,haltere" FBgn0264990 CG44141 http://flybase.net/reports/FBgn0264990.html protein_coding_gene CG44141 16-Dec-15 2015_12 FBgn0266851 CR45312 http://flybase.net/reports/FBgn0266851.html non_protein_coding_gene CR45312 16-Dec-15 2015_12 FBgn0083312 E(smoDN)1411 Enhancer of smoDN 1411 http://flybase.net/reports/FBgn0083312.html gene 16-Dec-15 2015_12 FBgn0037826 CG14689 http://flybase.net/reports/FBgn0037826.html protein_coding_gene 0019902=phosphatase binding 0010923=negative regulation of phosphatase activity IPR026142=Protein phosphatase 1 regulatory subunit 36 CG14689 16-Dec-15 2015_12 ENSMUSG00000052221(Gm70) ENSG00000165807(C14orf50) viable FBgn0065950 l(2)SH0079 lethal (2) SH0079 http://flybase.net/reports/FBgn0065950.html gene l(2)SH2 0079 16-Dec-15 2015_12 "lethal,recessive" FBgn0038981 CG5346 http://flybase.net/reports/FBgn0038981.html protein_coding_gene "0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 0055114=oxidation-reduction process "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR027443=Isopenicillin N synthase-like, IPR026992=Non-haem dioxygenase N-terminal domain" CG5346 16-Dec-15 2015_12 viable DRSC15778 E -0.341765182 -0.639149619 3.528378989 0.633052156 0.640747805 0.118389453 FBgn0036733 U4-U6-60K U4-U6 small nuclear riboprotein factor 60K http://flybase.net/reports/FBgn0036733.html protein_coding_gene "0017070=U6 snRNA binding, 0030621=U4 snRNA binding" "0000398=mRNA splicing, via spliceosome, 0008380=RNA splicing" "0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005688=U6 snRNP, 0005687=U4 snRNP, 0005681=spliceosomal complex" "CG6322, Prp4, U4/U6-60K" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR014906=Pre-mRNA processing factor 4 (PRP4)-like, IPR019775=WD40 repeat, conserved site, IPR027106=U4/U6 small nuclear ribonucleoprotein Prp4" CG6322 16-Dec-15 2015_12 ENSDARG00000067639(prpf4) YPR178W(PRP4) WBGene00007972(prp-4) ENSXETG00000026231(PRPF4) ENSMUSG00000066148(Prpf4) ENSG00000136875(PRPF4) lethal FBgn0041255 E3 E3 http://flybase.net/reports/FBgn0041255.html gene 16-Dec-15 2015_12 FBgn0043873 nertoo nertoo http://flybase.net/reports/FBgn0043873.html gene 16-Dec-15 2015_12 FBgn0267376 SelR Selenoprotein R http://flybase.net/reports/FBgn0267376.html "FBgn0044460, FBgn0037847, FBgn0064792, FBgn0064887" protein_coding_gene "0070191=methionine-R-sulfoxide reductase activity, 0008270=zinc ion binding, 0033743=peptide-methionine (R)-S-oxide reductase activity" "0018206=peptidyl-methionine modification, 0030091=protein repair, 0007015=actin filament organization, 0030041=actin filament polymerization, 0007411=axon guidance, 0006979=response to oxidative stress, 0008407=chaeta morphogenesis, 0055114=oxidation-reduction process, 0007526=larval somatic muscle development" "0005829=cytosol, 0005654=nucleoplasm" "dMsrB, EP3340, CG6584, BcDNA:RH61230, SelR, BcDNA:RE36040, methionine-R-sulfoxide reductase, unnamed, Methionine-R-sulfoxide reductase, selR, MsrB" "IPR028427=Peptide methionine sulfoxide reductase, IPR002579=Peptide methionine sulphoxide reductase MrsB, IPR011057=Mss4-like" CG6584 16-Dec-15 2015_12 ENSDARG00000045658(msrb3) YCL033C(MXR2) WBGene00018419(F44E2.6) ENSXETG00000014305(MSRB3) ENSMUSG00000051236(Msrb3) ENSG00000174099(MSRB3) neuroanatomy defective "intersegmental nerve,macrochaeta,embryonic/larval somatic muscle | third instar larval stage,filamentous actin | third instar larval stagehow-24B,filamentous actin | third instar larval stageMef2.PR,intersegmental nerve branch ISNb of A1-7,synapseelav.PU" FBgn0000104 aperC abnormal proboscis extension reflex C http://flybase.net/reports/FBgn0000104.html gene "0007637=proboscis extension reflex, 0046716=muscle cell cellular homeostasis" 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive,cold sensitive,behavior defective,heat sensitive" "proboscis muscle 1,cold sensitive" FBgn0036767 CG16775 http://flybase.net/reports/FBgn0036767.html protein_coding_gene IPR024518=Domain of unknown function DUF3421 CG16775 16-Dec-15 2015_12 viable FBgn0011597 grap grape http://flybase.net/reports/FBgn0011597.html gene 16-Dec-15 2015_12 female sterile nurse cell FBgn0022384 Nbp70 Nuclear localization sequence-binding protein 70 http://flybase.net/reports/FBgn0022384.html gene 0008139=nuclear localization sequence binding 0006606=protein import into nucleus "0005634=nucleus, 0005829=cytosol" NBP70 16-Dec-15 2015_12 FBgn0070015 BG01128 BG01128 http://flybase.net/reports/FBgn0070015.html gene 16-Dec-15 2015_12 stress response defective FBgn0031540 CG3238 http://flybase.net/reports/FBgn0031540.html protein_coding_gene "0003678=DNA helicase activity, 0005524=ATP binding" "0006281=DNA repair, 0000723=telomere maintenance" "IPR010285=DNA helicase Pif1-like, IPR003840=DNA helicase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3238 16-Dec-15 2015_12 ENSDARG00000020289(pif1) "YHR031C(RRM3),YML061C(PIF1)" WBGene00004028(pif-1) ENSXETG00000009544(PIF1) ENSMUSG00000041064(Pif1) ENSG00000140451(PIF1) "viable,fertile" FBgn0036681 Obp73a Odorant-binding protein 73a http://flybase.net/reports/FBgn0036681.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG13027, DmelObp73a" IPR006170=Pheromone/general odorant binding protein CG13027 16-Dec-15 2015_12 FBgn0033979 Cyp6a19 Cyp6a19 http://flybase.net/reports/FBgn0033979.html protein_coding_gene "0005506=iron ion binding, 0004497=monooxygenase activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG10243, 6a19" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR002402=Cytochrome P450, E-class, group II, IPR017972=Cytochrome P450, conserved site" CG10243 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0267964 CG46244 http://flybase.net/reports/FBgn0267964.html protein_coding_gene Dm_2L:103252 CG46244 16-Dec-15 2015_12 FBgn0263705 Myo10A Myosin 10A http://flybase.net/reports/FBgn0263705.html "FBgn0030252, FBgn0030255, FBgn0030254" protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled, 0005515=protein binding, 0005524=ATP binding" "0007391=dorsal closure, 0006886=intracellular protein transport, 0046847=filopodium assembly" "0043025=neuronal cell body, 0030175=filopodium, 0016461=unconventional myosin complex, 0016459=myosin complex" "CG16922, DmXV, Sisyphus, 10A, CG43657, unconventional myosin class XV, Syph, AAF47980, myo10A, CG2174, CG2136, myosin XV, Myosin XV" "IPR000299=FERM domain, IPR019748=FERM central domain, IPR000857=MyTH4 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000048=IQ motif, EF-hand binding site, IPR001609=Myosin head, motor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019749=Band 4.1 domain" CG43657 16-Dec-15 2015_12 ENSMUSG00000042678(Myo15) ENSG00000091536(MYO15A) FBgn0058117 CG40117 http://flybase.net/reports/FBgn0058117.html protein_coding_gene 16-Dec-15 2015_12 FBgn0044003 Su(rst)C233 Su(rst)C233 http://flybase.net/reports/FBgn0044003.html gene 0001745=compound eye morphogenesis C233 16-Dec-15 2015_12 FBgn0266858 CR45319 http://flybase.net/reports/FBgn0266858.html non_protein_coding_gene CR45319 16-Dec-15 2015_12 FBgn0005515 l(1)DC371 lethal (1) DC371 http://flybase.net/reports/FBgn0005515.html gene 16-Dec-15 2015_12 "lethal,male fertile,heat sensitive" FBgn0004777 Ccp84Ag Ccp84Ag http://flybase.net/reports/FBgn0004777.html FBgn0063076 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "BcDNA:RE04513, CG2342, cuticle cluster 2, Ccp, DmelCcp84Ag, cc2, BG:DS00004.7, unnamed" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG2342 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0050053 CG30053 http://flybase.net/reports/FBgn0050053.html FBgn0033768 protein_coding_gene CG8769 CG30053 16-Dec-15 2015_12 viable FBgn0044398 Scim29 Sensitized chromosome inheritance modifier 29 http://flybase.net/reports/FBgn0044398.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0025171 l(2)38De lethal (2) 38De http://flybase.net/reports/FBgn0025171.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260353 GSd112 http://flybase.net/reports/FBgn0260353.html gene 16-Dec-15 2015_12 lethal FBgn0041632 F-element\gag-r F element gag-related http://flybase.net/reports/FBgn0041632.html FBgn0020013 transposable_element_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "F-ORF1, F\ORF1" "IPR006579=Pre-C2HC domain, IPR001878=Zinc finger, CCHC-type" 16-Dec-15 2015_12 " embryonic stage , adult stage && oogenesis stage , embryonic stage | blastoderm " " embryonic/larval muscle system

, follicle cell

, embryonic central nervous system

, embryonic/larval salivary gland

,

posterior , embryonic/larval tracheal system

, testis

, embryonic/larval foregut

, nurse cell

, amnioserosa

" FBgn0005508 l(2)24EFf lethal (2) 24EFf http://flybase.net/reports/FBgn0005508.html gene l(2)Gr.VI 16-Dec-15 2015_12 "lethal,recessive" FBgn0266165 CR44871 http://flybase.net/reports/FBgn0266165.html non_protein_coding_gene CR44871 16-Dec-15 2015_12 FBgn0266810 CR45272 http://flybase.net/reports/FBgn0266810.html non_protein_coding_gene CR45272 16-Dec-15 2015_12 FBgn0004070 fs(2)mel4 female sterile (2) maternal effect lethal 4 http://flybase.net/reports/FBgn0004070.html gene mel 4 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,mouth hooks,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,metathoracic ventral denticle belt,mesothoracic ventral denticle belt,prothoracic ventral denticle belt,stomodeum" FBgn0010676 l(2)rK639 lethal (2) rK639 http://flybase.net/reports/FBgn0010676.html gene 16-Dec-15 2015_12 "lethal,recessive" "crystal cell,mitotic cell cycle" FBgn0001670 l(1)EN6 lethal (1) from Eugene Nonautonomous 6 http://flybase.net/reports/FBgn0001670.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval fat body,Malpighian tubule" FBgn0051498 CG31498 http://flybase.net/reports/FBgn0051498.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0267296 CR45732 http://flybase.net/reports/FBgn0267296.html non_protein_coding_gene CR45732 16-Dec-15 2015_12 FBgn0267652 pre-mod(mdg4)-N http://flybase.net/reports/FBgn0267652.html protein_coding_gene CG45990 CG45990 16-Dec-15 2015_12 FBgn0084184 W184 W184 http://flybase.net/reports/FBgn0084184.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0024574 l(3)rH304 lethal (3) rH304 http://flybase.net/reports/FBgn0024574.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085485 CG34456 http://flybase.net/reports/FBgn0085485.html "FBgn0035979, FBan0004446" protein_coding_gene 0005737=cytoplasm CG4446 CG34456 16-Dec-15 2015_12 FBgn0083076 ms(2)kn66 ms(2)kn66 http://flybase.net/reports/FBgn0083076.html gene 16-Dec-15 2015_12 FBgn0002059 l(2)40Fd lethal (2) 40Fd http://flybase.net/reports/FBgn0002059.html gene "40Fd, l(2Lh)Fd, GroupVIII" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" "wing,femur" FBgn0069121 ms(3)Z2420 ms(3)Z2420 http://flybase.net/reports/FBgn0069121.html gene 0007283=spermatogenesis 16-Dec-15 2015_12 male sterile spermatid FBgn0264906 CR44097 http://flybase.net/reports/FBgn0264906.html non_protein_coding_gene CR44097 16-Dec-15 2015_12 FBgn0085352 CG34323 http://flybase.net/reports/FBgn0085352.html protein_coding_gene "IPR000253=Forkhead-associated (FHA) domain, IPR008984=SMAD/FHA domain" CG34323 16-Dec-15 2015_12 FBgn0014322 l(3)ry15 lethal (3) ry15 http://flybase.net/reports/FBgn0014322.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260251 GSd325 http://flybase.net/reports/FBgn0260251.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "intersegmental nerve,segmental nerve,embryonic somatic muscle,ventral nerve cord" FBgn0022368 Pt-5 Larval protein-5 http://flybase.net/reports/FBgn0022368.html gene 16-Dec-15 2015_12 FBgn0004935 Altered-abdomen Altered abdomen http://flybase.net/reports/FBgn0004935.html gene Aa 16-Dec-15 2015_12 "visible,dominant" tergite FBgn0267625 CR45963 http://flybase.net/reports/FBgn0267625.html non_protein_coding_gene CR45963 16-Dec-15 2015_12 FBgn0030680 CG8944 http://flybase.net/reports/FBgn0030680.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR006578=MADF domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG8944 16-Dec-15 2015_12 "YLR375W(STP3),YDL048C(STP4)" "viable,visible" mesothoracic tergum DRSC21342 K -0.571161174 0.533526205 -0.187333621 0.523137273 -0.507376374 1.525100589 FBgn0065656 l(2)SH0721 lethal (2) SH0721 http://flybase.net/reports/FBgn0065656.html gene l(2)SH2 0721 16-Dec-15 2015_12 "lethal,recessive" FBgn0002906 Blm Bloom syndrome helicase ortholog http://flybase.net/reports/FBgn0002906.html FBgn0015800 protein_coding_gene "0003678=DNA helicase activity, 0008094=DNA-dependent ATPase activity, 0004386=helicase activity, 0005524=ATP binding, 0043140=ATP-dependent 3'-5' DNA helicase activity, 0000403=Y-form DNA binding, 0004003=ATP-dependent DNA helicase activity" "0006303=double-strand break repair via nonhomologous end joining, 0000724=double-strand break repair via homologous recombination, 0032508=DNA duplex unwinding, 0007131=reciprocal meiotic recombination, 0000732=strand displacement, 0000731=DNA synthesis involved in DNA repair, 0045003=double-strand break repair via synthesis-dependent strand annealing, 0006974=cellular response to DNA damage stimulus, 0006281=DNA repair, 0006260=DNA replication, 0000733=DNA strand renaturation, 0006302=double-strand break repair, 1901291=negative regulation of double-strand break repair via single-strand annealing" 0005634=nucleus "bloom, blm, ku70, dmblm, mutagen-sensitive 309, bloom syndrome helicase, RecQ, DmKu70, DmBLM, mus309, genome stabilizer 1, RecQ-like, Bloom helicase, Dmblm, gesta1, Bloom syndrome helicase, Drosophila Blm, Mus309, MUS309, BLM, Bloom's helicase, DmBlm, mus 309, Blm, dBLM, CG6920, Ku70" "IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR004589=DNA helicase, ATP-dependent, RecQ type, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR002121=HRDC domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR010997=HRDC-like, IPR018982=RQC domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6920 16-Dec-15 2015_12 YMR190C(SGS1) WBGene00001865(him-6) ENSMUSG00000030528(Blm) ENSG00000197299(BLM) embryonic stage -- adult stage "radiation sensitive,recessive,increased cell death,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,chemical sensitive,female sterile,male sterile,partially,DNA repair defective,semidominant,dominant,viable,wild-type,fertile" "wing disc,syncytial blastoderm embryo,maternal effect" FBgn0020882 alan alae angustae http://flybase.net/reports/FBgn0020882.html gene 16-Dec-15 2015_12 visible wing FBgn0262461 mir-315 mir-315 stem loop http://flybase.net/reports/FBgn0262461.html "FBgn0067689, FBgn0262329" miRNA_gene "0030177=positive regulation of Wnt signaling pathway, 0010629=negative regulation of gene expression, 0035195=gene silencing by miRNA" "dme-mir-315, miR-315, mir-315, CR33619, CR43036, pre-mir-315" CR43036 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of P-stage,some die during P-stage" "eye,wing,wing pouch,ectopic" FBgn0003065 CG2150 http://flybase.net/reports/FBgn0003065.html protein_coding_gene "anon-Pen100DE, GCR1, GCR 1, Pen100DE, GCR-1, pen100DE" CG2150 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0267946 CR46226 http://flybase.net/reports/FBgn0267946.html non_protein_coding_gene lincRNA.720 CR46226 16-Dec-15 2015_12 FBgn0023438 hl halteroptera http://flybase.net/reports/FBgn0023438.html gene 16-Dec-15 2015_12 "visible,recessive" "haltere,metathoracic segment" FBgn0250827 whip whipple http://flybase.net/reports/FBgn0250827.html "FBgn0085247, FBgn0061202, FBgn0061201" protein_coding_gene "CG34218, whip, whipple, NEST:bs36g01, CG2149, NEST:bs34h06" CG34218 16-Dec-15 2015_12 FBgn0267224 CR45664 http://flybase.net/reports/FBgn0267224.html non_protein_coding_gene CR45664 16-Dec-15 2015_12 FBgn0034281 CG14490 http://flybase.net/reports/FBgn0034281.html protein_coding_gene IPR003409=MORN motif CG14490 16-Dec-15 2015_12 ENSDARG00000021697 ENSMUSG00000029477(Morn3) ENSG00000139714(MORN3) viable FBgn0063449 Uhg2 U snoRNA host gene 2 http://flybase.net/reports/FBgn0063449.html non_protein_coding_gene "Dros-UHG2, CR32873, dUhg2, dUHG2" CR32873 16-Dec-15 2015_12 DRSC01100 E -1.356605913 -0.770445335 3.104442768 0.746955651 0.347129281 0.196847117 FBgn0052729 CG32729 http://flybase.net/reports/FBgn0052729.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003094 pkh pinkish http://flybase.net/reports/FBgn0003094.html gene 16-Dec-15 2015_12 FBgn0069136 mcl(3)Z6256 mcl(3)Z6256 http://flybase.net/reports/FBgn0069136.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0086039 snoRNA:Me28S-A2113 http://flybase.net/reports/FBgn0086039.html snoRNA_gene "Me28S-A2113, 28S-Am2113, snoRNA:28S-A2113, CR34668" CR34668 16-Dec-15 2015_12 FBgn0000606 eve even skipped http://flybase.net/reports/FBgn0000606.html "FBgn0014159, FBgn0014984, FBgn0015483, FBgn0017400, FBgn0019712, FBgn0019718, FBgn0019720, FBgn0019721, FBgn0019816, FBgn0023205" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0001709=cell fate determination, 0009997=negative regulation of cardioblast cell fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0035289=posterior head segmentation, 0008045=motor neuron axon guidance, 0050770=regulation of axonogenesis, 0007512=adult heart development, 0007366=periodic partitioning by pair rule gene, 0035290=trunk segmentation, 0008595=anterior/posterior axis specification, embryo, 0007376=cephalic furrow formation, 0007377=germ-band extension, 0007507=heart development, 0007417=central nervous system development, 0003007=heart morphogenesis, 0007399=nervous system development, 0007350=blastoderm segmentation, 0045165=cell fate commitment, 1901739=regulation of myoblast fusion, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "F, Eve, Group V, l(2)46Ce, Even skipped, V, unnamed, l(2)46Cg, VI, dm-eve, E(eve), Complementation group F, evenskip, Even Skipped, 14.10, l(2)46CFg, l(2)46CFp, lethal(2)46Ce, even-skipped, even, EVEN-SKIPPED, evenskipped, CG2328, Even-Skipped, l(2)46CFj, 20.35, Even-skipped, eve2, even-skiped, l(2)46CFh, Evenskipped, 10.9, EVE, 10.5, Group VI" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain" CG2328 16-Dec-15 2015_12 WBGene00015651(C09G12.1) "ENSMUSG00000001815(Evx2),ENSMUSG00000005503(Evx1)" "ENSG00000106038(EVX1),ENSG00000174279(EVX2)" " embryonic stage | stage 4-12 , embryonic stage | stage 1-15 , larval stage , embryonic stage | stage 1-17 , embryonic stage | stage 3 , embryonic stage | stage >12 " " parasegment 1,3,5,7,9,11,13

,

20-70% egg length , parasegment 1--14

, ganglion mother cell | segmentally repeated

" " embryonic stage | stage 13 , embryonic stage | stage 8-12 , embryonic stage | blastoderm , embryonic stage | stage 4-5 , embryonic stage | stage >12 , embryonic stage | stage 12 , embryonic stage , embryonic stage | stage 3-11 " " embryonic pericardial cell | subset

, parasegment 1--14

,

pair rule , organism | pair rule

, neurogenic region

, abdominal dorsal acute muscle 1

, proctodeum | presumptive

, cardioblast

, parasegment 1,3,5,7,9,11,13

" "lethal,recessive,developmental rate defective,viable,heat sensitive,pair rule phenotype,wild-type,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell death,cell polarity defective,somatic clone,partially lethal - majority die,some die during pupal stage" "parasegment 4,parasegment 5,parasegment 6,extended germ band embryo,embryonic segment,embryonic/first instar larval cuticle,parasegment 3,embryo,cuticle,parasegment,,adult heart,abdominal segment,RP2 motor neuron,aCC neuron,pCC neuron,embryonic mesothoracic segment,eve5,pericardial cell,abdominal dorsal acute muscle,presumptive embryonic/larval nervous system,embryonic/larval visceral muscle,embryonic/larval somatic muscle,cephalic furrow,intersegmental nerve,mitotic domain 2,embryonic/larval fat body,parasegment 1,eve1,ectoderm,U neuron,abdominal intersegmental nerve,mesothoracic intersegmental nerve,metathoracic intersegmental nerve,prothoracic intersegmental nerve,VUM neuron,presumptive embryonic/larval central nervous system,germ band,cardioblast,heart primordium,cardiac outflow muscle,embryonic/larval heart anchoring cell,embryonic heart anchoring cell primordium,ftz.ng,adult hindgut primordium,dMP2 neuron,dorsal transverse muscle,ventral acute muscle 2,nucleus" FBgn0039463 CG18472 http://flybase.net/reports/FBgn0039463.html protein_coding_gene "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG18472 16-Dec-15 2015_12 ENSDARG00000025882(zgc:56178) ENSXETG00000007369(dyx1c1) ENSMUSG00000032210(Dyx1c1) viable FBgn0259570 B2023 http://flybase.net/reports/FBgn0259570.html gene 16-Dec-15 2015_12 visible "anterior crossvein,tarsal segment" FBgn0001892 l(2)21Df lethal (2) 21Df http://flybase.net/reports/FBgn0001892.html gene "l(2)neh6, l(2)neh-6" 16-Dec-15 2015_12 lethal FBgn0016920 nompC no mechanoreceptor potential C http://flybase.net/reports/FBgn0016920.html "FBgn0001928, FBgn0031704, FBgn0031705" protein_coding_gene "0008092=cytoskeletal protein binding, 0008381=mechanically-gated ion channel activity, 0005261=cation channel activity, 0005262=calcium channel activity, 0030506=ankyrin binding, 0005216=ion channel activity" "0007605=sensory perception of sound, 0050954=sensory perception of mechanical stimulus, 0007638=mechanosensory behavior, 0010996=response to auditory stimulus, 0001964=startle response, 0050975=sensory perception of touch, 0050974=detection of mechanical stimulus involved in sensory perception, 0070588=calcium ion transmembrane transport, 0071260=cellular response to mechanical stimulus, 0006816=calcium ion transport, 0040011=locomotion, 0006812=cation transport, 0050976=detection of mechanical stimulus involved in sensory perception of touch" "0034703=cation channel complex, 0005929=cilium, 0030425=dendrite, 0043025=neuronal cell body" "jf24, l(2)jf24, TRPN1, unnamed, nomp, No mechanoreceptor potential C, NompC, TRPN, CG11020, NOMPC, lethal(2)25Dc, DmNompC, No Mechano-receptor Potential C, ORE-13, l(2)25Dc, CT30855, CG17468" "IPR002153=Transient receptor potential channel, canonical, IPR005821=Ion transport domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG11020 16-Dec-15 2015_12 ENSDARG00000023692(trpn1) WBGene00006616(trp-4) ENSXETG00000023747() "ENSMUSG00000014496(Ankrd28),ENSMUSG00000052331(Ankrd44),ENSMUSG00000014498(Ankrd52)" "ENSG00000206560(ANKRD28),ENSG00000065413(ANKRD44),ENSG00000139645(ANKRD52)" " pharate adult stage , pupal stage | late " " macrochaeta &&of proboscis

, microchaeta

, mechanosensory sensory organ

, Johnston's organ

, leg sensillum

, macrochaeta

, chordotonal organ &&of haltere

" "neurophysiology defective,auditory perception defective,lethal - all die before end of embryonic stage,recessive,behavior defective,locomotor behavior defective,uncoordinated,some die during embryonic stage,wild-type,touch sensitivity defective,lethal - all die before end of larval stage,some die during third instar larval stage,touch perception defective,neuroanatomy defective,viable" "local interneuron of adult antennal lobe,antenna,adult antennal nerve,leg,macrochaeta,wing,arista,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0265627 CG44435 http://flybase.net/reports/FBgn0265627.html FBgn0034374 protein_coding_gene CG15086 CG44435 16-Dec-15 2015_12 viable FBgn0002504 l(3)SG64 lethal (3) SG64 http://flybase.net/reports/FBgn0002504.html gene "l(3)g131, l(3)g30R" 16-Dec-15 2015_12 "lethal,recessive" FBgn0013498 l(1)LB lethal (1) of Luers and Belitz http://flybase.net/reports/FBgn0013498.html gene 16-Dec-15 2015_12 lethal FBgn0053702 CG33702 http://flybase.net/reports/FBgn0053702.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33702 16-Dec-15 2015_12 FBgn0050033 CG30033 http://flybase.net/reports/FBgn0050033.html "FBgn0047047, FBgn0061370" protein_coding_gene "BcDNA:RH63918, BcDNA:RH07028" CG30033 16-Dec-15 2015_12 viable FBgn0032755 CG17344 http://flybase.net/reports/FBgn0032755.html FBgn0063745 protein_coding_gene BcDNA:AT10305 CG17344 16-Dec-15 2015_12 viable FBgn0259266 C373 http://flybase.net/reports/FBgn0259266.html gene 16-Dec-15 2015_12 visible "wing,chaeta" FBgn0020353 anon-32ABa anon-32ABa http://flybase.net/reports/FBgn0020353.html gene 503 16-Dec-15 2015_12 FBgn0042643 flexin flexin http://flybase.net/reports/FBgn0042643.html gene 16-Dec-15 2015_12 synapseunspecified FBgn0032040 CG13386 http://flybase.net/reports/FBgn0032040.html protein_coding_gene CG13386 16-Dec-15 2015_12 viable FBgn0082347 HM421 HM421 http://flybase.net/reports/FBgn0082347.html gene 16-Dec-15 2015_12 FBgn0040107 lectin-21Ca lectin-21Ca http://flybase.net/reports/FBgn0040107.html FBgn0031272 protein_coding_gene "0030246=carbohydrate binding, 0005534=galactose binding" 0032504=multicellular organism reproduction 0005576=extracellular region "AC004573a, CG2826, AC 004573A, Lectin21Ca, Lectin-21Ca" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG2826 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000008874(Clec3a),ENSMUSG00000025784(Clec3b),ENSMUSG00000004473(Clec11a)" ENSG00000163815(CLEC3B) viable FBgn0003557 Su(dx) Suppressor of deltex http://flybase.net/reports/FBgn0003557.html "FBgn0043511, FBgn0043512, FBgn0043513" protein_coding_gene "0005112=Notch binding, 0004842=ubiquitin-protein transferase activity, 0019904=protein domain specific binding" "0032880=regulation of protein localization, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0008586=imaginal disc-derived wing vein morphogenesis, 0031623=receptor internalization, 0007219=Notch signaling pathway, 0008587=imaginal disc-derived wing margin morphogenesis, 0045746=negative regulation of Notch signaling pathway, 0019915=lipid storage, 0016348=imaginal disc-derived leg joint morphogenesis, 0016567=protein ubiquitination" "0005938=cell cortex, 0005634=nucleus, 0005737=cytoplasm" "Suppressor of Deltex, AIP4, anon-WO0073329.1, anon-WO0073329.2, Su(Dx), su(dx), ITCH, CG4244, Itch, anon-WO0073329.4, Su(deltex), suppressor of deltex" "IPR001202=WW domain, IPR000569=HECT domain, IPR000008=C2 domain" CG4244 16-Dec-15 2015_12 ENSDARG00000061345(zgc:154036) WBGene00007009(wwp-1) ENSXETG00000019475(ITCH) "ENSMUSG00000041058(Wwp1),ENSMUSG00000027598(Itch),ENSMUSG00000031930(Wwp2)" "ENSG00000123124(WWP1),ENSG00000078747(ITCH),ENSG00000198373(WWP2)" pupal stage wing | restricted

"visible,recessive,heat sensitive,somatic clone,partially lethal - majority die,lethal,viable" "wing vein,crossvein,follicle cell,somatic clone,follicle cell & nucleus | somatic clone,heat sensitive,wing vein L4,wing vein L5,wing vein L2,ectopic,wing margin,wing disc,tarsal segment,sex comb,supernumerary,tarsal segment & jointptc-559.1,wing,wing vein L3,leg,dorsocentral bristle" FBgn0037889 scpr-A SCP-containing protein A http://flybase.net/reports/FBgn0037889.html protein_coding_gene 0032504=multicellular organism reproduction "0005576=extracellular region, 0005615=extracellular space" "scp-A, SCPR-A, cg5207, CG5207, SCP-Related-A, bs03f04.y1" "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG5207 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0061110 l(3)S006930b lethal (3) S006930b http://flybase.net/reports/FBgn0061110.html gene 0069/30 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0062596 Mod(var)1535 Mod(var)1535 http://flybase.net/reports/FBgn0062596.html gene 0006342=chromatin silencing 1535 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0019750 l(1)815-3 lethal (1) 815-3 http://flybase.net/reports/FBgn0019750.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085652 CG41491 http://flybase.net/reports/FBgn0085652.html FBan0041491 protein_coding_gene 16-Dec-15 2015_12 FBgn0085584 CG41262 http://flybase.net/reports/FBgn0085584.html FBan0041262 protein_coding_gene 16-Dec-15 2015_12 FBgn0085422 CG34393 http://flybase.net/reports/FBgn0085422.html "FBgn0031509, FBgn0031508" protein_coding_gene 0005088=Ras guanyl-nucleotide exchange factor activity "0046579=positive regulation of Ras protein signal transduction, 0043547=positive regulation of GTPase activity" "CG15405, CG8829, Dm_2L:14421" "IPR030710=Ras-GEF domain-containing family member 1B, IPR023578=Ras guanine nucleotide exchange factor domain, IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR001895=Ras guanine-nucleotide exchange factors catalytic domain" CG34393 16-Dec-15 2015_12 viable FBgn0261381 mtTFB1 Mitochondrial Transcription Factor B1 http://flybase.net/reports/FBgn0261381.html "FBgn0261354, FBgn0036197" protein_coding_gene "0000179=rRNA (adenine-N6,N6-)-dimethyltransferase activity, 0003712=transcription cofactor activity, 0016433=rRNA (adenine) methyltransferase activity" "0000154=rRNA modification, 0006417=regulation of translation, 0006390=transcription from mitochondrial promoter" "0005759=mitochondrial matrix, 0005739=mitochondrion" "d-mtTFB1, CG7319, CG42631, mitochondrial translation factor B1, mitochondrial transcription factor B1, TFB1, d-TFB1M" "IPR001737=Ribosomal RNA adenine methyltransferase KsgA/Erm, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR023165=rRNA adenine dimethylase-like, IPR020596=Ribosomal RNA adenine methylase transferase, conserved site, IPR020598=Ribosomal RNA adenine methylase transferase, N-terminal, IPR011530=Ribosomal RNA adenine dimethylase" CG42631 16-Dec-15 2015_12 FBgn0050497 CG30497 http://flybase.net/reports/FBgn0050497.html "FBgn0033218, FBgn0033219, FBgn0045081, FBgn0045786, FBgn0062190" protein_coding_gene "0005829=cytosol, 0005654=nucleoplasm" "NEST:bs36c04, anon-WO0118547.176, CG1557, CG30947, CG1383, EP(2)2618, BEST:LD33067" "IPR012937=FAM46 family, IPR011989=Armadillo-like helical" CG30497 16-Dec-15 2015_12 "ENSDARG00000011797(fam46bb),ENSDARG00000039943(fam46b),ENSDARG00000037183,ENSDARG00000054641(zgc:171771),ENSDARG00000010437(fam46c),ENSDARG00000062830" WBGene00004131(pqn-44) "viable,fertile,neuroanatomy defective" longitudinal connective FBgn0060513 l(3)S104011b lethal (3) S104011b http://flybase.net/reports/FBgn0060513.html gene 1040/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0002819 ms(2)3R male sterile (2) 3R http://flybase.net/reports/FBgn0002819.html gene 16-Dec-15 2015_12 "male sterile,recessive,female sterile,cytokinesis defective,male" "spermatozoon,spermatid,Nebenkern,Nebenkern derivative,spermatocyte" FBgn0051459 CG31459 http://flybase.net/reports/FBgn0051459.html "FBgn0045145, FBgn0045418, FBgn0063302" protein_coding_gene "NEST:bs29d02, NEST:bs03f05, BcDNA:AT26603" CG31459 16-Dec-15 2015_12 viable FBgn0029012 l(3)77CDm lethal (3) 77CDm http://flybase.net/reports/FBgn0029012.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032125 Cpr30B Cuticular protein 30B http://flybase.net/reports/FBgn0032125.html protein_coding_gene "0008011=structural constituent of pupal chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr30B, CG3818" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG3818 16-Dec-15 2015_12 "viable,visible,body color defective" mesothoracic tergum FBgn0030441 CG2209 http://flybase.net/reports/FBgn0030441.html FBgn0044773 protein_coding_gene anon-WO0140519.110 CG2209 16-Dec-15 2015_12 viable FBgn0267864 CR46152 http://flybase.net/reports/FBgn0267864.html pseudogene_attribute CG12717-related CR46152 16-Dec-15 2015_12 FBgn0015566 zaro zarolho http://flybase.net/reports/FBgn0015566.html gene 0007601=visual perception 16-Dec-15 2015_12 FBgn0267995 CR46262 http://flybase.net/reports/FBgn0267995.html non_protein_coding_gene CR46262 16-Dec-15 2015_12 FBgn0060912 l(3)S042806b lethal (3) S042806b http://flybase.net/reports/FBgn0060912.html gene 0428/06 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0053240 Ste:CG33240 Ste:CG33240 http://flybase.net/reports/FBgn0053240.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33240" "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet" CG33240 16-Dec-15 2015_12 FBgn0026359 Su(Raf)43B Su(Raf)43B http://flybase.net/reports/FBgn0026359.html gene 16-Dec-15 2015_12 FBgn0062619 Mod(var)1200 Mod(var)1200 http://flybase.net/reports/FBgn0062619.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1200 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0065195 l(2)SH2324 lethal (2) SH2324 http://flybase.net/reports/FBgn0065195.html gene l(2)SH2 2324 16-Dec-15 2015_12 "lethal,recessive" FBgn0014394 tete tete http://flybase.net/reports/FBgn0014394.html gene "tete, c47, te" 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0033020 COX4L Cytochrome c oxidase subunit 4-like http://flybase.net/reports/FBgn0033020.html "FBan0041444, FBgn0084009, FBgn0063752" protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" "0005739=mitochondrion, 0005751=mitochondrial respiratory chain complex IV" "COXIV, IV, Cytochrome c oxidase Subunit IV, Cytochrome c oxidase subunit IV, CX42, COX IV, BcDNA:AT07685, cox4, CX41, CG10396" "IPR013288=Cytochrome c oxidase subunit IV, IPR004203=Cytochrome c oxidase subunit IV family" CG10396 16-Dec-15 2015_12 "ENSDARG00000032970(cox4i1),ENSDARG00000022509(zgc:73355),ENSDARG00000012388(LOC402880)" "ENSXETG00000004473(cox4i1),ENSXETG00000027592(COX4I2)" "ENSMUSG00000031818(Cox4i1),ENSMUSG00000009876(Cox4i2)" "ENSG00000131055(COX4I2),ENSG00000131143(COX4I1)" viable FBgn0002511 l(3)Sp1 lethal (3) Sp1 http://flybase.net/reports/FBgn0002511.html gene 16-Dec-15 2015_12 lethal FBgn0053631 CG33631 http://flybase.net/reports/FBgn0053631.html FBgn0037784 protein_coding_gene CG12808 IPR010512=Protein of unknown function DUF1091 CG33631 16-Dec-15 2015_12 FBgn0040665 CG13593 http://flybase.net/reports/FBgn0040665.html protein_coding_gene 16-Dec-15 2015_12 FBgn0061127 l(3)S003302b lethal (3) S003302b http://flybase.net/reports/FBgn0061127.html gene 0033/02 16-Dec-15 2015_12 lethal FBgn0024696 e(if)1 enhancer of inflated 1 http://flybase.net/reports/FBgn0024696.html gene 16-Dec-15 2015_12 FBgn0033519 CG11825 http://flybase.net/reports/FBgn0033519.html FBgn0063044 protein_coding_gene 0055070=copper ion homeostasis "BcDNA:RE25483, dHIG1" "IPR007667=Hypoxia induced protein, domain" CG11825 16-Dec-15 2015_12 ENSDARG00000022303(hig1) "ENSXETG00000006171(hig1a),ENSXETG00000025166(hig1b),ENSXETG00000003392(HIGD1B)" "ENSMUSG00000038412(Higd1a),ENSMUSG00000044330(Gm9790),ENSMUSG00000020928(Higd1b)" "ENSG00000181061(HIGD1A),ENSG00000214511(HIGD1C),ENSG00000131097(HIGD1B)" viable FBgn0022067 l(2)k07914 lethal (2) k07914 http://flybase.net/reports/FBgn0022067.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263019 CR43314 http://flybase.net/reports/FBgn0263019.html "FBgn0051863, FBgn0041606" non_protein_coding_gene pri-mir-263a CR43314 16-Dec-15 2015_12 FBgn0002265 l(3)69Ad lethal (3) 69Ad http://flybase.net/reports/FBgn0002265.html gene "l(3)rsg27, rsg27, rose-gespleten region interval 27, l(3)62-3" 16-Dec-15 2015_12 lethal FBgn0060511 l(3)S104207b lethal (3) S104207b http://flybase.net/reports/FBgn0060511.html gene 1042/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0011850 tRNA:E4:56Fc transfer RNA:glu4:56Fc http://flybase.net/reports/FBgn0011850.html "FBgn0003771, FBgn0011846, FBgn0050451, FBgn0060239" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033459=GAA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002787.trna6-GluTTC, CR30451, tRNA:Glu, glu-tRNA-4, chr2R.trna64-GluTTC, tRNA:E:TTC:AE002787-c, tRNA:E4, tRNA:glu4:56Fc" CR30451 16-Dec-15 2015_12 FBgn0017379 l(1)EA65 lethal (1) EA65 http://flybase.net/reports/FBgn0017379.html gene EA65 16-Dec-15 2015_12 FBgn0022350 anon-Y anon-Y http://flybase.net/reports/FBgn0022350.html gene gene Y 16-Dec-15 2015_12 FBgn0061481 snafu snafu http://flybase.net/reports/FBgn0061481.html gene "0007143=female meiotic division, 0007067=mitotic nuclear division" 16-Dec-15 2015_12 FBgn0031335 CG5565 http://flybase.net/reports/FBgn0031335.html protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process 28557659 "IPR006439=HAD hydrolase, subfamily IA, IPR023214=HAD-like domain" CG5565 16-Dec-15 2015_12 YKL033W-A() WBGene00020113(R151.10) viable FBgn0266455 CG45080 http://flybase.net/reports/FBgn0266455.html protein_coding_gene CG45080 16-Dec-15 2015_12 FBgn0004431 LysX Lysozyme X http://flybase.net/reports/FBgn0004431.html "FBgn0002575, FBgn0063089" protein_coding_gene 0003796=lysozyme activity "0006952=defense response, 0019730=antimicrobial humoral response" "BcDNA:LP09906, CG9120, lysX" "IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR019799=Glycoside hydrolase, family 22, conserved site, IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain" CG9120 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) " pupal stage | early , embryonic stage -- adult stage , larval stage | third instar " embryonic/larval midgut

FBgn0001867 l(1)X27 lethal (1) X27 http://flybase.net/reports/FBgn0001867.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "ventral nerve cord,presumptive embryonic/larval central nervous system,gastrula embryo,ventral furrow,embryonic/larval midgut,embryonic/larval hindgut,presumptive embryonic/larval digestive system,embryonic/larval somatic muscle,ectoderm" FBgn0004017 wl whirly http://flybase.net/reports/FBgn0004017.html gene 16-Dec-15 2015_12 visible acrostichal bristle FBgn0002320 l(3)85Ed lethal (3) 85Ed http://flybase.net/reports/FBgn0002320.html gene 16-Dec-15 2015_12 lethal FBgn0001496 l(1)10Bj lethal (1) 10Bj http://flybase.net/reports/FBgn0001496.html gene "10Bj, l(1)G23" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0002081 l(2)49Fj lethal (2) 49Fj http://flybase.net/reports/FBgn0002081.html gene "vr-19, l(2)vr19" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,non-suppressor of variegation,dominant" FBgn0034309 CG14498 http://flybase.net/reports/FBgn0034309.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033205 CG2064 http://flybase.net/reports/FBgn0033205.html FBgn0046213 protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process 0012505=endomembrane system BcDNA:SD07613 "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR" CG2064 16-Dec-15 2015_12 "ENSDARG00000045277(rdh12l),ENSDARG00000018069(rdh12),ENSDARG00000068474(si:dkey-94e7.2),ENSDARG00000058966(zgc:112332),ENSDARG00000071660,ENSDARG00000008491(LOC407663),ENSDARG00000054797(zgc:153441)" YOR246C() WBGene00000985(dhs-22) ENSXETG00000008385(rdh13) ENSMUSG00000008435(Rdh13) ENSG00000160439(RDH13) viable FBgn0265423 CG44335 http://flybase.net/reports/FBgn0265423.html protein_coding_gene "lincRNA.706, lincRNA.707" CG44335 16-Dec-15 2015_12 FBgn0029158 Las Lipoic acid synthase http://flybase.net/reports/FBgn0029158.html FBgn0036989 protein_coding_gene "0016992=lipoate synthase activity, 0051539=4 iron, 4 sulfur cluster binding" 0009107=lipoate biosynthetic process 0005739=mitochondrion CG5231 "IPR006638=Elongator protein 3/MiaB/NifB, IPR007197=Radical SAM, IPR013785=Aldolase-type TIM barrel, IPR003698=Lipoyl synthase" CG5231 16-Dec-15 2015_12 ENSDARG00000022845(lias) YOR196C(LIP5) WBGene00010809(M01F1.3) ENSXETG00000012839(LIAS) ENSMUSG00000029199(Lias) ENSG00000121897(LIAS) viable FBgn0032914 CG14397 http://flybase.net/reports/FBgn0032914.html protein_coding_gene CG14397 16-Dec-15 2015_12 FBgn0025821 I-t inhibitor-t http://flybase.net/reports/FBgn0025821.html protein_coding_gene 0004864=protein phosphatase inhibitor activity 0035308=negative regulation of protein dephosphorylation "CG14719, Inhibitor-t, pp1d6" CG14719 16-Dec-15 2015_12 viable FBgn0036712 brv2 brivido-2 http://flybase.net/reports/FBgn0036712.html protein_coding_gene "0005262=calcium channel activity, 0005509=calcium ion binding" "0048812=neuron projection morphogenesis, 0050960=detection of temperature stimulus involved in thermoception, 0070417=cellular response to cold, 0006816=calcium ion transport" 0016020=membrane "CT33194, CG16793" "IPR003915=Polycystic kidney disease type 2 protein, IPR013122=Polycystin cation channel, PKD1/PKD2" CG16793 16-Dec-15 2015_12 "cold stress response defective,recessive" FBgn0014383 scy scratched eye http://flybase.net/reports/FBgn0014383.html gene scylla 16-Dec-15 2015_12 FBgn0011440 l(3)j13B3 lethal (3) j13B3 http://flybase.net/reports/FBgn0011440.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266160 CR44866 http://flybase.net/reports/FBgn0266160.html non_protein_coding_gene CR44866 16-Dec-15 2015_12 FBgn0054054 CG34054 http://flybase.net/reports/FBgn0054054.html FBgn0082661 protein_coding_gene "HDC05792, BP1079, unnamed" CG34054 16-Dec-15 2015_12 FBgn0267083 CR45527 http://flybase.net/reports/FBgn0267083.html non_protein_coding_gene CR45527 16-Dec-15 2015_12 FBgn0036495 CG33259 http://flybase.net/reports/FBgn0036495.html FBgn0053259 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG7489 "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG33259 16-Dec-15 2015_12 "WBGene00044921(F53C11.9),WBGene00015683(C10G8.4)" viable DRSC10854 E 0.176172967 -0.310144143 -0.559548569 1.643617035 -0.247992136 -0.605057689 FBgn0265926 CR44715 http://flybase.net/reports/FBgn0265926.html non_protein_coding_gene CR44715 16-Dec-15 2015_12 FBgn0027961 l(3)S146004 lethal (3) S146004 http://flybase.net/reports/FBgn0027961.html gene 1460/04 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0086064 snoRNA:Me28S-G3113b http://flybase.net/reports/FBgn0086064.html snoRNA_gene "CR34693, Me28S-Gm3113b" CR34693 16-Dec-15 2015_12 FBgn0024644 l(2)k11002 lethal (2) k11002 http://flybase.net/reports/FBgn0024644.html gene 110/2 16-Dec-15 2015_12 "lethal,recessive" FBgn0053795 CG33795 http://flybase.net/reports/FBgn0053795.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33795 16-Dec-15 2015_12 FBgn0267202 CR45642 http://flybase.net/reports/FBgn0267202.html non_protein_coding_gene CR45642 16-Dec-15 2015_12 FBgn0033813 fsd fates-shifted http://flybase.net/reports/FBgn0033813.html protein_coding_gene "0005515=protein binding, 0004842=ubiquitin-protein transferase activity" "0031647=regulation of protein stability, 0009952=anterior/posterior pattern specification, 0035167=larval lymph gland hemopoiesis, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "FBXO14, CG12765" "IPR026509=Transmembrane protein 183, IPR001810=F-box domain" CG12765 16-Dec-15 2015_12 ENSDARG00000044899(tmem183a) ENSXETG00000002408(BC076989.1) ENSMUSG00000042305(Tmem183a) ENSG00000163444(TMEM183A) "viable,embryonic/larval segmentation phenotype,maternal effect,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" cephalic furrow FBgn0004419 me31B maternal expression at 31B http://flybase.net/reports/FBgn0004419.html FBgn0022123 protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005515=protein binding, 0005524=ATP binding, 0003723=RNA binding" "0035195=gene silencing by miRNA, 0033962=cytoplasmic mRNA processing body assembly, 0090328=regulation of olfactory learning, 0050688=regulation of defense response to virus, 0046959=habituation, 0007095=mitotic G2 DNA damage checkpoint, 0007279=pole cell formation" "0000932=cytoplasmic mRNA processing body, 0005737=cytoplasm, 0043186=P granule, 0005875=microtubule associated complex" "CG4916, Me31b, Me31B, ME31B, Maternal expression at 31B, DmRH3, DDX6, l(2)k06607, Mat31B, Dhh1p/Me31b" "IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site" CG4916 16-Dec-15 2015_12 ENSDARG00000061338(si:ch211-147p17.1) YDL160C(DHH1) WBGene00000479(cgh-1) ENSXETG00000010061(DDX6) ENSMUSG00000032097(Ddx6) ENSG00000110367(DDX6) "viable,lethal,recessive,wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,learning defective" "egg chamber,germline clone,germline cell,nurse cell & nucleus | germ-line clone,oocyte,ring canal" DRSC03569 E -0.783340184 0.85447016 -3.574064433 -3.884511917 0.418355931 1.238734598 FBgn0041004 CG17715 http://flybase.net/reports/FBgn0041004.html "FBan0017715, FBgn0041003, FBgn0047070, FBgn0063069" protein_coding_gene "BcDNA:RE07178, CG18603, BcDNA:RE63764" IPR019537=Transmembrane protein 65 CG17715 16-Dec-15 2015_12 WBGene00044325(tag-321) viable FBgn0260872 CG42582 http://flybase.net/reports/FBgn0260872.html protein_coding_gene mdcds_57926 16-Dec-15 2015_12 FBgn0034328 IM23 Immune induced molecule 23 http://flybase.net/reports/FBgn0034328.html FBgn0046997 protein_coding_gene "0019731=antibacterial humoral response, 0008063=Toll signaling pathway, 0009617=response to bacterium, 0050830=defense response to Gram-positive bacterium, 0006952=defense response" 0005576=extracellular region "CG15066, BcDNA:RH67033, DIM-23, DIM 23, Immune-induced peptide 23 precursor" IPR013172=Immune-induced protein Dim CG15066 16-Dec-15 2015_12 viable FBgn0004743 l(3)85Dj lethal (3) 85Dj http://flybase.net/reports/FBgn0004743.html gene 16-Dec-15 2015_12 lethal FBgn0002346 l(3)87Cb lethal (3) 87Cb http://flybase.net/reports/FBgn0002346.html gene l(3)SzB 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037399 Or83c Odorant receptor 83c http://flybase.net/reports/FBgn0037399.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "CG15581, DOR116, 83c, 83D.1" "IPR004117=Olfactory receptor, Drosophila" CG15581 16-Dec-15 2015_12 "smell perception defective,neurophysiology defective,viable,chemosensitive behavior defective" antennal intermediate sensillum I2 FBgn0005407 l(1)11Ag lethal (1) 11Ag http://flybase.net/reports/FBgn0005407.html gene 16-Dec-15 2015_12 lethal FBgn0025748 l(3)95Ay lethal (3) 95Ay http://flybase.net/reports/FBgn0025748.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016871 l(2)39Ad lethal (2) 39Ad http://flybase.net/reports/FBgn0016871.html "FBgn0016872, FBgn0016873, FBgn0016874" gene "l(2)39Ag, l(2)39Ae, l(2)39Af" 16-Dec-15 2015_12 lethal FBgn0085332 CG34303 http://flybase.net/reports/FBgn0085332.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG34303 16-Dec-15 2015_12 FBgn0082963 snoRNA:ë¬28S-3378 snoRNA:ë¬28S-3378 http://flybase.net/reports/FBgn0082963.html snoRNA_gene "psi28S-3378, CR34549, Psi 28S-3378, Psi28S-3378" CR34549 16-Dec-15 2015_12 FBgn0014356 ms(3)HB366 ms(3)HB366 http://flybase.net/reports/FBgn0014356.html gene heterochron 16-Dec-15 2015_12 FBgn0066365 dyl dusky-like http://flybase.net/reports/FBgn0066365.html FBgn0035530 protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0016476=regulation of embryonic cell shape, 0007160=cell-matrix adhesion, 0007015=actin filament organization, 0003383=apical constriction" 0016324=apical plasma membrane "CG15013, Dusky-like" IPR001507=Zona pellucida domain CG15013 16-Dec-15 2015_12 "WBGene00008978(cutl-3),WBGene00009041(cut-3),WBGene00000851(cut-1),WBGene00008482(cut-4),WBGene00011104(cut-5)" "viable,fertile,visible" trichogen cell FBgn0039585 CG1894 http://flybase.net/reports/FBgn0039585.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "0006355=regulation of transcription, DNA-templated" dmHAG407 "IPR002717=Histone acetyltransferase domain, MYST-type, IPR016181=Acyl-CoA N-acyltransferase" CG1894 16-Dec-15 2015_12 viable FBgn0267156 CR45596 http://flybase.net/reports/FBgn0267156.html non_protein_coding_gene CR45596 16-Dec-15 2015_12 FBgn0016846 l(1)N26 lethal (1) N26 http://flybase.net/reports/FBgn0016846.html gene N26 16-Dec-15 2015_12 "lethal,recessive" FBgn0033165 CG11113 http://flybase.net/reports/FBgn0033165.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG11113 16-Dec-15 2015_12 FBgn0036351 CG14107 http://flybase.net/reports/FBgn0036351.html protein_coding_gene CG14107 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC10110 IE 0.313546561 1.681444017 0.258710283 -2.116526508 -0.133401931 0.339957725 FBgn0070056 19 19 http://flybase.net/reports/FBgn0070056.html gene 0001754=eye photoreceptor cell differentiation #19 16-Dec-15 2015_12 FBgn0042141 CG18818 http://flybase.net/reports/FBgn0042141.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267658 CR45996 http://flybase.net/reports/FBgn0267658.html non_protein_coding_gene lincRNA.807 CR45996 16-Dec-15 2015_12 FBgn0085753 28SrRNA-ë¬:CR40596 28S ribosomal RNA pseudogene:CR40596 http://flybase.net/reports/FBgn0085753.html FBan0040596 pseudogene_attribute CR40596 CR40596 16-Dec-15 2015_12 FBgn0014165 four-play four-play http://flybase.net/reports/FBgn0014165.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0035280 Cpr62Bb Cuticular protein 62Bb http://flybase.net/reports/FBgn0035280.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr62Bb, CG13935" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG13935 16-Dec-15 2015_12 viable FBgn0032911 tadr torn and diminished rhabdomeres http://flybase.net/reports/FBgn0032911.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport 0016020=membrane CG9264 IPR002293=Amino acid/polyamine transporter I CG9264 16-Dec-15 2015_12 "viable,neurophysiology defective,fertile" rhabdomere FBgn0267231 CR45671 http://flybase.net/reports/FBgn0267231.html non_protein_coding_gene CR45671 16-Dec-15 2015_12 FBgn0064163 l(4)A6 lethal (4) A6 http://flybase.net/reports/FBgn0064163.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065966 l(2)SH0013 lethal (2) SH0013 http://flybase.net/reports/FBgn0065966.html gene l(2)SH2 0013 16-Dec-15 2015_12 "lethal,recessive" FBgn0029959 Rab39 Rab39 http://flybase.net/reports/FBgn0029959.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032482=Rab protein signal transduction, 0015031=protein transport, 0016192=vesicle-mediated transport" "0005770=late endosome, 0043025=neuronal cell body, 0031982=vesicle, 0045202=synapse" "AAF46271, 24640395, CG12156, rab39, DmRab39" "IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12156 16-Dec-15 2015_12 "ENSDARG00000019312(zgc:165464),ENSDARG00000036501(rab39b),ENSDARG00000034215(zgc:73061)" WBGene00004286(rab-39) "ENSMUSG00000031202(Rab39b),ENSMUSG00000055069(Rab39)" "ENSG00000155961(RAB39B),ENSG00000179331(RAB39)" "viable,visible" mesothoracic tergum FBgn0002129 l(2)K202 lethal (2) K202 http://flybase.net/reports/FBgn0002129.html gene 16-Dec-15 2015_12 lethal FBgn0060866 l(3)S047222 lethal (3) S047222 http://flybase.net/reports/FBgn0060866.html gene 0472/22 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011444 l(3)j15E7 lethal (3) j15E7 http://flybase.net/reports/FBgn0011444.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002347 l(3)87Cc lethal (3) 87Cc http://flybase.net/reports/FBgn0002347.html gene l(3)SzC 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0065351 l(2)SH1798 lethal (2) SH1798 http://flybase.net/reports/FBgn0065351.html gene l(2)SH2 1798 16-Dec-15 2015_12 "lethal,recessive" FBgn0260603 2L0948 http://flybase.net/reports/FBgn0260603.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0001641 l(1)dn21 lethal (1) discs normal 21 http://flybase.net/reports/FBgn0001641.html gene l(1)d.norm.-21 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0261802 CG42748 http://flybase.net/reports/FBgn0261802.html "FBgn0032978, FBan0015216, FBgn0032976, FBan0006448, FBgn0032977, FBgn0044604" protein_coding_gene 0008157=protein phosphatase 1 binding "0005886=plasma membrane, 0016328=lateral plasma membrane" "CG6448, CG15217, anon-WO0140519.28, CG15216" CG42748 16-Dec-15 2015_12 ENSMUSG00000029419(Gm996) FBgn0020785 rr red ring http://flybase.net/reports/FBgn0020785.html gene 16-Dec-15 2015_12 "viable,fertile,eye color defective" "eye,ommatidium,pigment cell" FBgn0032769 CG10750 http://flybase.net/reports/FBgn0032769.html protein_coding_gene IPR025252=Domain of unknown function DUF4200 CG10750 16-Dec-15 2015_12 ENSDARG00000035550(LOC100001777) "ENSG00000186710(CCDC42B),ENSG00000161973(CCDC42)" viable FBgn0032515 loqs loquacious http://flybase.net/reports/FBgn0032515.html protein_coding_gene "0003725=double-stranded RNA binding, 0005515=protein binding" "0007417=central nervous system development, 0030718=germ-line stem cell maintenance, 0010586=miRNA metabolic process, 0031054=pre-miRNA processing, 0070918=production of small RNA involved in gene silencing by RNA, 0070920=regulation of production of small RNA involved in gene silencing by RNA, 0030422=production of siRNA involved in RNA interference, 0048132=female germ-line stem cell asymmetric division, 0009047=dosage compensation by hyperactivation of X chromosome" "0005737=cytoplasm, 0016442=RISC complex" "Loqs, Loquacious, R3D1-S, R3D1-L, loquacious, CG6866, LOQS, cg6866, dRax, loq, R3D1, TRBP, r3d1" IPR014720=Double-stranded RNA-binding domain CG6866 16-Dec-15 2015_12 ENSDARG00000070471(tarbp2) ENSXETG00000012644(tarbp2) "ENSMUSG00000002731(Prkra),ENSMUSG00000023051(Tarbp2)" "ENSG00000139546(TARBP2),ENSG00000180228(PRKRA)" "viable,female sterile,recessive,male sterile,partially,male semi-sterile,locomotor behavior defective,neuroanatomy defective,lethal,short lived,conditional,lethal - all die before end of embryonic stage,paternal effect,some die during embryonic stage,rescuable maternal effect,non-suppressor of variegation,male fertile,fertile" "testis,ovary,ovariole,germarium,female germline stem cell,follicle cell,spectrosome,egg chamber,ventral nerve cord commissure,longitudinal connective,eye,retina,conditional,lamina,germline clone,dorsal appendage,germline stem cell" FBgn0051709 CG31709 http://flybase.net/reports/FBgn0051709.html "FBgn0045777, FBgn0063624" protein_coding_gene BEST:LP04712 CG31709 16-Dec-15 2015_12 viable FBgn0000417 darky darky http://flybase.net/reports/FBgn0000417.html gene "dar, da" 16-Dec-15 2015_12 "visible,male sterile,partially lethal - majority die,viable,male,poor,body color defective" "cuticle,wing,adult cuticle" FBgn0050395 CG30395 http://flybase.net/reports/FBgn0050395.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG30395 16-Dec-15 2015_12 viable FBgn0265546 CR44396 http://flybase.net/reports/FBgn0265546.html non_protein_coding_gene CR44396 16-Dec-15 2015_12 FBgn0030642 CG15642 http://flybase.net/reports/FBgn0030642.html protein_coding_gene "IPR019184=Uncharacterised protein family, transmembrane-17" CG15642 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0039425 CG5432 http://flybase.net/reports/FBgn0039425.html protein_coding_gene 0004332=fructose-bisphosphate aldolase activity 0006096=glycolytic process "IPR029769=Fructose-bisphosphate aldolase class-I, eukaryotic-type, IPR000741=Fructose-bisphosphate aldolase, class-I, IPR013785=Aldolase-type TIM barrel" CG5432 16-Dec-15 2015_12 "ENSDARG00000011665(aldoaa),ENSDARG00000034470(aldoab),ENSDARG00000019702(aldocb),ENSDARG00000053684(aldob),ENSDARG00000057661(aldoca)" "WBGene00011474(aldo-1),WBGene00017166(aldo-2)" "ENSXETG00000027677(aldoc),ENSXETG00000020674(aldoa),ENSXETG00000024058(aldob)" viable DRSC15799 E 1.242056616 -0.219548144 1.788522727 -1.628003832 -0.489431626 -0.311132544 FBgn0022223 l(2)k03204 lethal (2) k03204 http://flybase.net/reports/FBgn0022223.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011786 l(3)06264 lethal (3) 06264 http://flybase.net/reports/FBgn0011786.html gene l(3)04264 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0001480 l(1)9Fh lethal (1) 9Fh http://flybase.net/reports/FBgn0001480.html gene "l(1)EF433, l(1)G4" 16-Dec-15 2015_12 lethal FBgn0260003 Dys Dystrophin http://flybase.net/reports/FBgn0260003.html "FBgn0000435, FBgn0024242, FBan0007344, FBgn0038710, FBgn0038711, FBgn0038713, FBgn0051175" protein_coding_gene "0008307=structural constituent of muscle, 0008092=cytoskeletal protein binding, 0050699=WW domain binding, 0003779=actin binding, 0005198=structural molecule activity, 0008270=zinc ion binding" "0007517=muscle organ development, 0048172=regulation of short-term neuronal synaptic plasticity, 0007274=neuromuscular synaptic transmission, 0046716=muscle cell cellular homeostasis, 0030010=establishment of cell polarity, 0008586=imaginal disc-derived wing vein morphogenesis, 0007474=imaginal disc-derived wing vein specification, 0046928=regulation of neurotransmitter secretion" "0016010=dystrophin-associated glycoprotein complex, 0005856=cytoskeleton, 0005737=cytoplasm, 0005938=cell cortex" "dystrophin, DLP2, DmDLP, DLP186, Dp117, dmDp186, GI3046716, Dp186, DLP3, CG31175, dys, dmDLP, Dys, Dystrophin-like protein 186, dmDys, det, Dp205, CG17750, Dystrophin-like protein 1, DLP1, DmDYS, CG34157, IDLP, CG7243, Dystrophin, CG7240, Dystrophin Dp186, DLP, detached, Dystrophin-like protein 3, CG7344, Dystrophin-like protein 2" "IPR000433=Zinc finger, ZZ-type, IPR015153=EF-hand domain, type 1, IPR002017=Spectrin repeat, IPR015154=EF-hand domain, type 2, IPR011992=EF-hand domain pair, IPR018159=Spectrin/alpha-actinin, IPR001202=WW domain, IPR001715=Calponin homology domain, IPR001589=Actinin-type actin-binding domain, conserved site" CG34157 16-Dec-15 2015_12 WBGene00001131(dys-1) "ENSXETG00000022290(),ENSXETG00000010561()" ENSMUSG00000045103(Dmd) "ENSG00000198947(DMD),ENSG00000152818(UTRN)" DRSC16220 EK -0.820606314 -0.583094626 1.600842411 -0.130368388 3.986557362 0.617476153 FBgn0039209 REPTOR Repressed by TOR http://flybase.net/reports/FBgn0039209.html FBgn0045886 protein_coding_gene "0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0038202=TORC1 signaling, 0045893=positive regulation of transcription, DNA-templated, 0044246=regulation of multicellular organismal metabolic process, 0042594=response to starvation" "0005737=cytoplasm, 0005634=nucleus" "repressed by TOR, DM23, DM24, CG13624, anon-WO0153538.65" IPR004827=Basic-leucine zipper domain CG13624 16-Dec-15 2015_12 ENSMUSG00000048249(A930001N09Rik) viable DRSC24359 K -0.255281191 0.541229535 0.121267756 0.799991361 2.435586401 0.489685221 FBgn0028873 CG31771 http://flybase.net/reports/FBgn0028873.html FBgn0051771 protein_coding_gene "BG:DS05899.6, DS05899.6" 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0002254 l(3)68Ef lethal (3) 68Ef http://flybase.net/reports/FBgn0002254.html gene "rsg16, l(3)rsg16, rose-gespleten region interval 16" 16-Dec-15 2015_12 lethal FBgn0265013 ed::Nrg http://flybase.net/reports/FBgn0265013.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0039987 CR12798 http://flybase.net/reports/FBgn0039987.html FBan0012798 pseudogene_attribute "CG12798, CT38386, SEK1/MKK4" CR12798 16-Dec-15 2015_12 FBgn0052299 CG32299 http://flybase.net/reports/FBgn0052299.html "FBgn0045244, FBgn0047328" protein_coding_gene "NEST:bs19a11, BcDNA:AT26229" CG32299 16-Dec-15 2015_12 viable FBgn0001126 gou gourd http://flybase.net/reports/FBgn0001126.html gene "0046843=dorsal appendage formation, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile FBgn0051360 CG31360 http://flybase.net/reports/FBgn0051360.html FBgn0063071 protein_coding_gene BcDNA:RE06652 IPR028036=Domain of unknown function DUF4536 CG31360 16-Dec-15 2015_12 viable FBgn0026718 fu12 fu12 http://flybase.net/reports/FBgn0026718.html protein_coding_gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity "0008654=phospholipid biosynthetic process, 0048149=behavioral response to ethanol" 0016020=membrane "AGPAT2, AGPAT1, CG17608" "IPR002123=Phospholipid/glycerol acyltransferase, IPR004552=1-acyl-sn-glycerol-3-phosphate acyltransferase" CG17608 16-Dec-15 2015_12 "viable,fertile,hyperactive,conditional,chemical resistant" FBgn0015440 l(1)5Da lethal (1) 5Da http://flybase.net/reports/FBgn0015440.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032845 CG10747 http://flybase.net/reports/FBgn0032845.html protein_coding_gene "0008081=phosphoric diester hydrolase activity, 0047396=glycosylphosphatidylinositol diacylglycerol-lyase activity" 0006650=glycerophospholipid metabolic process 38B.13 "IPR003633=Phospholipase C, variant-surface-glycoprotein, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG10747 16-Dec-15 2015_12 "ENSDARG00000071149(zgc:112023),ENSDARG00000054794(plcxd3),ENSDARG00000058493,ENSDARG00000071193,ENSDARG00000071156,ENSDARG00000058200(LOC559936),ENSDARG00000044335,ENSDARG00000055808,ENSDARG00000071155(zgc:64065),ENSDARG00000071194,ENSDARG00000071148,ENSDARG00000071139(LOC100151335)" WBGene00018184(F38E9.1) "ENSXETG00000009201(PLCXD2),ENSXETG00000003537(PLCXD3)" ENSMUSG00000049148(Plcxd3) ENSG00000182836(PLCXD3) "viable,fertile" FBgn0023002 laph larval phototaxis http://flybase.net/reports/FBgn0023002.html gene 16-Dec-15 2015_12 FBgn0000460 Daughter-killer Daughter killer http://flybase.net/reports/FBgn0000460.html gene Dk 16-Dec-15 2015_12 FBgn0264809 Arr1::Zzzz\NIa http://flybase.net/reports/FBgn0264809.html engineered_fusion_gene arrestin-TEV protease 16-Dec-15 2015_12 FBgn0028090 l(3)S082106 lethal (3) S082106 http://flybase.net/reports/FBgn0028090.html gene 0821/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0032702 CG10376 http://flybase.net/reports/FBgn0032702.html protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation "0005634=nucleus, 0005737=cytoplasm" PP2C "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C" CG10376 16-Dec-15 2015_12 "ENSDARG00000005786(ppm1f),ENSDARG00000026499(ppm1e)" WBGene00001412(fem-2) "ENSXETG00000018572(PPM1F),ENSXETG00000001119(PPM1E)" "ENSMUSG00000026181(Ppm1f),ENSMUSG00000046442(Ppm1e)" ENSG00000100034(PPM1F) viable FBgn0032871 CG2611 http://flybase.net/reports/FBgn0032871.html protein_coding_gene 38D.27 "IPR008590=Protein of unknown function DUF872, transmembrane" CG2611 16-Dec-15 2015_12 viable FBgn0036179 CG7368 http://flybase.net/reports/FBgn0036179.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006351=transcription, DNA-templated, 0006909=phagocytosis" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR027775=C2H2- zinc finger protein family, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7368 16-Dec-15 2015_12 WBGene00000483(che-1) viable DRSC10826 IK -1.935542915 0.849347215 0.452241778 0.681696603 3.012509062 1.129085403 FBgn0052613 CG32613 http://flybase.net/reports/FBgn0052613.html FBgn0047249 protein_coding_gene BcDNA:GM13088 16-Dec-15 2015_12 viable FBgn0031254 CG13692 http://flybase.net/reports/FBgn0031254.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0007264=small GTPase mediated signal transduction, 0006471=protein ADP-ribosylation" 0005622=intracellular "IPR024156=Small GTPase superfamily, ARF type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006689=Small GTPase superfamily, ARF/SAR type" CG13692 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0260302 GSd330 http://flybase.net/reports/FBgn0260302.html gene 16-Dec-15 2015_12 lethal FBgn0082337 HM696 HM696 http://flybase.net/reports/FBgn0082337.html gene 16-Dec-15 2015_12 FBgn0011109 l(1)Q70 lethal (1) Q70 http://flybase.net/reports/FBgn0011109.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0263621 CG43630 http://flybase.net/reports/FBgn0263621.html protein_coding_gene CG43630 16-Dec-15 2015_12 FBgn0023163 Su(mg)1-4 Suppressor of modifier of gypsy 1-4 http://flybase.net/reports/FBgn0023163.html gene 16-Dec-15 2015_12 FBgn0264634 carbuncle carbuncle http://flybase.net/reports/FBgn0264634.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0003287 Rst(2)amd ë± methyl dopa-resistant on 2 http://flybase.net/reports/FBgn0003287.html gene Resistance (2) alpha methyl dopa 16-Dec-15 2015_12 chemical resistant FBgn0046763 CG17278 http://flybase.net/reports/FBgn0046763.html FBgn0040577 protein_coding_gene 0030178=negative regulation of Wnt signaling pathway BcDNA:SD04019 IPR002350=Kazal domain CG17278 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal" "wing,wing blade,adult abdomen" DRSC15216 E -0.091745187 0.114555744 1.038112668 -2.358883087 0.101292823 -0.660009055 FBgn0002191 l(3)63Bb lethal (3) 63Bb http://flybase.net/reports/FBgn0002191.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035833 CG7565 http://flybase.net/reports/FBgn0035833.html protein_coding_gene 0004568=chitinase activity CT23145 "IPR013980=MANSC domain, IPR000742=EGF-like domain, IPR022409=PKD/Chitinase domain, IPR011106=Seven cysteines, N-terminal, IPR000601=PKD domain" CG7565 16-Dec-15 2015_12 ENSDARG00000035660(LOC794990) "ENSXETG00000009674(KIAA0319L),ENSXETG00000014827(KIAA0319)" "ENSMUSG00000028830(AU040320),ENSMUSG00000006711(D130043K22Rik)" "ENSG00000137261(KIAA0319),ENSG00000142687(KIAA0319L)" viable FBgn0004497 fs(1)ë_b3 female sterile (1) ë_b3 http://flybase.net/reports/FBgn0004497.html gene 16-Dec-15 2015_12 FBgn0040354 CG14418 http://flybase.net/reports/FBgn0040354.html FBgn0029638 protein_coding_gene EG:BACR43E12.5 CG14418 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0016859 l(1)N6 lethal (1) N6 http://flybase.net/reports/FBgn0016859.html gene N6 16-Dec-15 2015_12 "lethal,recessive" FBgn0011877 tRNA:Hë¬ transfer RNA:his:pseudogene http://flybase.net/reports/FBgn0011877.html "FBgn0050253, FBgn0060290" pseudogene_attribute "AE002787.trna36-Undet, CR30253, His-tRNA, tRNA:hisPsi, tRNA:-?:AE002787, chr2R.trna18-Undet???" CR30253 16-Dec-15 2015_12 FBgn0082593 eunuch eunuch http://flybase.net/reports/FBgn0082593.html gene 16-Dec-15 2015_12 FBgn0265578 CG44405 http://flybase.net/reports/FBgn0265578.html protein_coding_gene CG44405 16-Dec-15 2015_12 FBgn0085311 CG34282 http://flybase.net/reports/FBgn0085311.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG7710 IPR002557=Chitin binding domain CG34282 16-Dec-15 2015_12 viable FBgn0036193 CG14135 http://flybase.net/reports/FBgn0036193.html protein_coding_gene 0003676=nucleic acid binding "IPR006612=Zinc finger, C2CH-type, IPR013805=GrpE nucleotide exchange factor, coiled-coil" CG14135 16-Dec-15 2015_12 "ENSDARG00000055690,ENSDARG00000056213(LOC553397)" "viable,planar polarity defective" FBgn0020890 Su(osk)P16 Suppressor of oskar P16 http://flybase.net/reports/FBgn0020890.html gene P16 16-Dec-15 2015_12 FBgn0065541 l(2)SH1060 lethal (2) SH1060 http://flybase.net/reports/FBgn0065541.html gene l(2)SH2 1060 16-Dec-15 2015_12 "lethal,recessive" FBgn0052447 CG32447 http://flybase.net/reports/FBgn0052447.html "FBgn0037118, FBgn0037119, FBgn0046509, FBgn0046510" protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0005887=integral component of plasma membrane "CG14571, anon-WO0170980.77, CG7155, anon-WO0170980.76" "IPR017978=GPCR, family 3, C-terminal" CG32447 16-Dec-15 2015_12 viable FBgn0004159 l(2)51Eb lethal (2) 51Eb http://flybase.net/reports/FBgn0004159.html gene 16-Dec-15 2015_12 "lethal,polyphasic" FBgn0085783 CR41111 http://flybase.net/reports/FBgn0085783.html "FBan0041111, FBgn0069906" non_protein_coding_gene 16-Dec-15 2015_12 FBgn0016709 Reg-14 Rhythmically expressed gene 14 http://flybase.net/reports/FBgn0016709.html gene "Drosophila Rhythmically expressed gene 14, Dreg-14" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " adult head

FBgn0261286 Mat89Ba Maternal transcript 89Ba http://flybase.net/reports/FBgn0261286.html "FBgn0020408, FBgn0038410" protein_coding_gene 0003723=RNA binding "0022008=neurogenesis, 0006364=rRNA processing, 0009267=cellular response to starvation" "0000794=condensed nuclear chromosome, 0005730=nucleolus" CG12785 "IPR019355=Cell cycle regulator Mat89Bb, IPR005554=Nrap protein" CG12785 16-Dec-15 2015_12 ENSDARG00000059711(nol6) YGR090W(UTP22) WBGene00021789(nol-6) ENSXETG00000002153(NOL6) ENSMUSG00000028430(Nol6) ENSG00000165271(NOL6) " adult stage , adult stage && oogenesis stage | stage >=S10 , adult stage && oogenesis stage | stage S9-10 " " ovary

, oocyte

, nurse cell

" FBgn0267521 18SrRNA-ë¬:CR45861 18S ribosomal RNA pseudogene:CR45861 http://flybase.net/reports/FBgn0267521.html pseudogene_attribute CR45861 CR45861 16-Dec-15 2015_12 FBgn0036916 Mtr3 Mtr3 http://flybase.net/reports/FBgn0036916.html protein_coding_gene 0000175=3'-5'-exoribonuclease activity 0010468=regulation of gene expression "0000177=cytoplasmic exosome (RNase complex), 0005737=cytoplasm, 0000176=nuclear exosome (RNase complex)" "dMtr3, mtr3, CG8025" "IPR020568=Ribosomal protein S5 domain 2-type fold, IPR001247=Exoribonuclease, phosphorolytic domain 1, IPR015847=Exoribonuclease, phosphorolytic domain 2, IPR027408=PNPase/RNase PH domain" CG8025 16-Dec-15 2015_12 "partially lethal - majority die,visible" trichogen cell DRSC10953 E 0.15676239 -0.796504727 0.51526968 -1.841064335 0.357879212 0.561750107 FBgn0085708 CG41582 http://flybase.net/reports/FBgn0085708.html FBan0041582 protein_coding_gene 16-Dec-15 2015_12 FBgn0262063 EG28 http://flybase.net/reports/FBgn0262063.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052499 Cda4 Chitin deacetylase-like 4 http://flybase.net/reports/FBgn0052499.html "FBgn0031198, FBgn0031199, FBgn0031200, FBgn0040520, FBgn0063002" protein_coding_gene "0016810=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, 0008061=chitin binding" "0005975=carbohydrate metabolic process, 0022008=neurogenesis, 0006030=chitin metabolic process" 0098595=perivitelline space "CG12447, DmCDA4, CG13238, CG32499, BcDNA:RE51076, CG9557, CG9558" "IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002557=Chitin binding domain, IPR002509=NodB homology domain" CG32499 16-Dec-15 2015_12 "viable,lethal,neuroanatomy defective,fertile" ganglion mother cell FBgn0019843 anon-pp84 anon-pp84 http://flybase.net/reports/FBgn0019843.html gene pp84 16-Dec-15 2015_12 FBgn0026660 l(2)12A9 lethal (2) 12A9 http://flybase.net/reports/FBgn0026660.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0046874 Pif1B PFTAIRE-interacting factor 1B http://flybase.net/reports/FBgn0046874.html "FBgn0027540, FBgn0052940, FBgn0053720, FBtr0081936, FBpp0081418, FBtr0081937, FBpp0081419, FBtr0081938, FBpp0081420, FBtr0081939, FBpp0081421" protein_coding_gene 0005515=protein binding "CG9808, CG32940, CG33719/CG33720, Pif1, PIF-1B, BcDNA:GH12504, CG33720" CG33720 16-Dec-15 2015_12 FBgn0263867 CR43714 http://flybase.net/reports/FBgn0263867.html non_protein_coding_gene lincRNA.47 CR43714 16-Dec-15 2015_12 FBgn0019769 l(1)53 lethal (1) 53 http://flybase.net/reports/FBgn0019769.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035973 CG17179 http://flybase.net/reports/FBgn0035973.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265693 CR44500 http://flybase.net/reports/FBgn0265693.html non_protein_coding_gene lincRNA.960 CR44500 16-Dec-15 2015_12 FBgn0039691 IntS11 Integrator 11 http://flybase.net/reports/FBgn0039691.html protein_coding_gene "0016180=snRNA processing, 0034472=snRNA 3'-end processing, 0006379=mRNA cleavage, 0022008=neurogenesis, 0006378=mRNA polyadenylation" "0032039=integrator complex, 0005847=mRNA cleavage and polyadenylation specificity factor complex" "dRC-68, Int11, CG1972" "IPR011108=RNA-metabolising metallo-beta-lactamase, IPR001279=Metallo-beta-lactamase, IPR022712=Beta-Casp domain" CG1972 16-Dec-15 2015_12 ENSDARG00000025212(cpsf3l) WBGene00008642(F10B5.8) ENSMUSG00000029034(Cpsf3l) ENSG00000127054(CPSF3L) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0069166 mcl(3)Z1483 mcl(3)Z1483 http://flybase.net/reports/FBgn0069166.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0013340 Su(var)2-24 Su(var)2-24 http://flybase.net/reports/FBgn0013340.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant" FBgn0262650 l(2)47A9-5 lethal (2) 47A9-5 http://flybase.net/reports/FBgn0262650.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003323 sby small body http://flybase.net/reports/FBgn0003323.html gene "sby-61, sby-6a" 16-Dec-15 2015_12 "small body,viable,reduced,fertile,body color defective" FBgn0069147 mcl(3)Z3822 mcl(3)Z3822 http://flybase.net/reports/FBgn0069147.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0015398 kasa kasa http://flybase.net/reports/FBgn0015398.html gene 16-Dec-15 2015_12 FBgn0259412 C474.1 http://flybase.net/reports/FBgn0259412.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0023510 Rbcn-3B Rabconnectin-3B http://flybase.net/reports/FBgn0023510.html protein_coding_gene 0003924=GTPase activity "0007186=G-protein coupled receptor signaling pathway, 0008593=regulation of Notch signaling pathway, 0007035=vacuolar acidification" 0005834=heterotrimeric G-protein complex "FK39, CG17766, Rabconnectin-3beta, EG:86E4.3" "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG17766 16-Dec-15 2015_12 ENSDARG00000059329(LOC572502) WBGene00004314(rbc-2) ENSXETG00000020898() ENSMUSG00000040560(Wdr7) ENSG00000091157(WDR7) "lethal,recessive,viable,visible,body color defective" "follicle cell,somatic clone,mesothoracic tergum" FBgn0028182 l(3)S024151 lethal (3) S024151 http://flybase.net/reports/FBgn0028182.html gene 0241/51 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0265906 CR44695 http://flybase.net/reports/FBgn0265906.html non_protein_coding_gene CR44695 16-Dec-15 2015_12 FBgn0023000 mth methuselah http://flybase.net/reports/FBgn0023000.html protein_coding_gene "0004930=G-protein coupled receptor activity, 0008528=G-protein coupled peptide receptor activity, 0042277=peptide binding, 0005515=protein binding" "0016079=synaptic vesicle exocytosis, 0009408=response to heat, 0007186=G-protein coupled receptor signaling pathway, 0042594=response to starvation, 0007568=aging, 0008340=determination of adult lifespan, 0006979=response to oxidative stress, 1901562=response to paraquat, 0000302=response to reactive oxygen species" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "Mth, MTH, methusalah, CG6936, Methuselah" "IPR023311=Methuselah ectodomain, domain 2, IPR010596=Methuselah, N-terminal domain, IPR017981=GPCR, family 2-like, IPR000832=GPCR, family 2, secretin-like" CG6936 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,neurophysiology defective,stress response defective,neuroanatomy defective,long lived,chemical resistant,fertile,wild-type" "synapse,synaptic vesicle,male germline stem cell" FBgn0053641 CG33641 http://flybase.net/reports/FBgn0053641.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33641 16-Dec-15 2015_12 viable FBgn0040798 CG13069 http://flybase.net/reports/FBgn0040798.html protein_coding_gene CG13069 16-Dec-15 2015_12 viable FBgn0031077 CG15618 http://flybase.net/reports/FBgn0031077.html protein_coding_gene 0030488=tRNA methylation 0005737=cytoplasm "IPR016024=Armadillo-type fold, IPR019442=Domain of unknown function DUF2428, death-receptor-like" CG15618 16-Dec-15 2015_12 ENSMUSG00000024251(Thada) ENSG00000115970(THADA) "viable,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0266313 CR44978 http://flybase.net/reports/FBgn0266313.html non_protein_coding_gene CR44978 16-Dec-15 2015_12 FBgn0016838 l(1)MZ6 lethal (1) MZ6 http://flybase.net/reports/FBgn0016838.html gene M6 16-Dec-15 2015_12 "lethal,recessive" FBgn0261061 Sfp96F Seminal fluid protein 96F http://flybase.net/reports/FBgn0261061.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG42609 16-Dec-15 2015_12 FBgn0065629 l(2)SH0788 lethal (2) SH0788 http://flybase.net/reports/FBgn0065629.html gene l(2)SH2 0788 16-Dec-15 2015_12 "lethal,recessive" FBgn0028959 Au Auricular http://flybase.net/reports/FBgn0028959.html gene 16-Dec-15 2015_12 "visible,dominant" eye FBgn0030578 CG5347 http://flybase.net/reports/FBgn0030578.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR000571=Zinc finger, CCCH-type, IPR018957=Zinc finger, C3HC4 RING-type, IPR001841=Zinc finger, RING-type" CG5347 16-Dec-15 2015_12 "ENSDARG00000041665(mkrn1),ENSDARG00000007630(mkrn2)" WBGene00021924(Y55F3AM.6) ENSXETG00000027117() "ENSMUSG00000029922(Mkrn1),ENSMUSG00000070527(Mkrn3),ENSMUSG00000000439(Mkrn2)" "ENSG00000133606(MKRN1),ENSG00000179455(MKRN3),ENSG00000075975(MKRN2)" viable FBgn0033594 CG13226 http://flybase.net/reports/FBgn0033594.html protein_coding_gene CG13226 16-Dec-15 2015_12 viable FBgn0011675 ner nervig http://flybase.net/reports/FBgn0011675.html gene 16-Dec-15 2015_12 FBgn0262686 CG43156 http://flybase.net/reports/FBgn0262686.html protein_coding_gene lincRNA.980 CG43156 16-Dec-15 2015_12 FBgn0011938 tRNA:N5:42Ah transfer RNA:asn5:42Ah http://flybase.net/reports/FBgn0011938.html "FBgn0003759, FBgn0050305, FBgn0050513, FBgn0060130" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033442=AAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30513, CR30305, Asn-tRNA-8, tRNA:N:GTT:AE002769-d, tRNA[Asn], tRNA:asn5:42Ah, Asn8, chr2R.trna99-AsnGTT, AE002769.trna8-AsnGTT" CR30513 16-Dec-15 2015_12 FBgn0002457 l(3)SG10 lethal (3) SG10 http://flybase.net/reports/FBgn0002457.html gene l(3)m27 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033323 CG12376 http://flybase.net/reports/FBgn0033323.html FBgn0044550 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane anon-WO0140519.77 IPR004837=Sodium/calcium exchanger membrane region CG12376 16-Dec-15 2015_12 "WBGene00003574(ncx-9),WBGene00003573(ncx-8),WBGene00003575(ncx-10),WBGene00003571(ncx-6)" ENSMUSG00000032754(Slc24a6) ENSG00000089060(SLC24A6) viable FBgn0053147 Hs3st-A Heparan sulfate 3-O sulfotransferase-A http://flybase.net/reports/FBgn0053147.html "FBgn0034384, FBgn0034385, FBgn0034386, FBgn0050123, FBgn0050124" protein_coding_gene 0008467=[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity "CG15075, CG30123, CG33147, dHS3OSTA, CG30124, CG15076, CG15074, lincRNA.S3111" "IPR000863=Sulfotransferase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG33147 16-Dec-15 2015_12 "ENSDARG00000067967,ENSDARG00000035578(hs3st1l2),ENSDARG00000012249" "ENSXETG00000020230(),ENSXETG00000006969(HS3ST1)" ENSMUSG00000044499(Hs3st5) ENSG00000175818 "lethal,viable,fertile" FBgn0005757 l(1)TK401 lethal (1) TK401 http://flybase.net/reports/FBgn0005757.html gene l401 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0041166 anon-C1 anon-C1 http://flybase.net/reports/FBgn0041166.html gene C1 16-Dec-15 2015_12 FBgn0024627 l(2)k16514 lethal (2) k16514 http://flybase.net/reports/FBgn0024627.html gene 165/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0029644 CG14421 http://flybase.net/reports/FBgn0029644.html protein_coding_gene CG14421 16-Dec-15 2015_12 FBgn0035754 MED4 Mediator complex subunit 4 http://flybase.net/reports/FBgn0035754.html protein_coding_gene "0003713=transcription coactivator activity, 0001104=RNA polymerase II transcription cofactor activity, 0005515=protein binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint, 0007406=negative regulation of neuroblast proliferation, 0048813=dendrite morphogenesis" "0016592=mediator complex, 0005634=nucleus" "med4, Med4/TRAP36, Mediator, Trap36, CG8609, dTRAP36, p34, dp34, Med4" "IPR019258=Mediator complex, subunit Med4" CG8609 16-Dec-15 2015_12 ENSDARG00000041503(med4) WBGene00007012(mdt-4) ENSXETG00000000549(Q5M8Y7_XENTR) ENSMUSG00000022109(Med4) ENSG00000136146(MED4) "viable,visible" mesothoracic tergum DRSC11014 IK -0.3617063 3.037334515 -0.773862229 0.346684398 2.14059791 1.876380757 FBgn0052208 825-Oak 825-Oak http://flybase.net/reports/FBgn0052208.html protein_coding_gene CG32208 CG32208 16-Dec-15 2015_12 FBgn0051386 CR31386 http://flybase.net/reports/FBgn0051386.html FBgn0047113 non_protein_coding_gene "Neuropeptide-like precursor 3, BcDNA:RE39877, CG31386" CR31386 16-Dec-15 2015_12 FBgn0259842 Su(Ste):CR42411 Su(Ste):CR42411 http://flybase.net/reports/FBgn0259842.html non_protein_coding_gene CR42411 CR42411 16-Dec-15 2015_12 FBgn0027494 RpS10a Ribosomal protein S10a http://flybase.net/reports/FBgn0027494.html FBgn0039534 protein_coding_gene 0003735=structural constituent of ribosome "0022008=neurogenesis, 0006412=translation" "0005737=cytoplasm, 0022627=cytosolic small ribosomal subunit" "RpS10, S10, BcDNA:LD32148, CG12275" "IPR005326=Plectin/S10, N-terminal" CG12275 16-Dec-15 2015_12 ENSDARG00000034897(rps10) "YOR293W(RPS10A),YMR230W(RPS10B)" WBGene00004479(rps-10) ENSXETG00000015129(rps10) "ENSMUSG00000052146(Rps10),ENSMUSG00000063427" "ENSG00000101278,ENSG00000124614(RPS10),ENSG00000215464" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC26061 K -0.166139991 0.711166095 0.501474075 0.440097046 1.307640835 1.605754294 FBgn0005471 l(1)ts639 lethal (1) ts639 http://flybase.net/reports/FBgn0005471.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0065297 l(2)SH1996 lethal (2) SH1996 http://flybase.net/reports/FBgn0065297.html gene l(2)SH2 1996 16-Dec-15 2015_12 "lethal,recessive" FBgn0060374 l(3)S136613 lethal (3) S136613 http://flybase.net/reports/FBgn0060374.html gene 1366/13 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0015823 T-B7.2 T-B7.2 http://flybase.net/reports/FBgn0015823.html gene 16-Dec-15 2015_12 FBgn0260585 2L2870 http://flybase.net/reports/FBgn0260585.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0036101 NijA Ninjurin A http://flybase.net/reports/FBgn0036101.html FBgn0062835 protein_coding_gene "0007155=cell adhesion, 0007411=axon guidance, 0042246=tissue regeneration" 0016021=integral component of membrane "ninA, NijA, ninjurin A, CG6449, Ninjurin A" IPR007007=Ninjurin CG6449 16-Dec-15 2015_12 ENSXETG00000015640(ninj1) "ENSMUSG00000037966(Ninj1),ENSMUSG00000041377(Ninj2)" "increased cell death,viable,lethal,lethal - all die during pupal stage,fertile" "embryonic/larval lymph gland | larval stage,embryonic/larval hemocyte | larval stage,S2 cell-line" FBgn0046113 GluRIIC Glutamate receptor IIC http://flybase.net/reports/FBgn0046113.html FBgn0031293 protein_coding_gene "0008066=glutamate receptor activity, 0004970=ionotropic glutamate receptor activity, 0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity" "0007274=neuromuscular synaptic transmission, 0030510=regulation of BMP signaling pathway, 0035249=synaptic transmission, glutamatergic, 0007268=synaptic transmission, 0006811=ion transport, 0045184=establishment of protein localization" "0031594=neuromuscular junction, 0045202=synapse, 0008328=ionotropic glutamate receptor complex, 0097482=muscle cell postsynaptic density" "GluRC, GLURIIC, Glutamate receptor III, GluRIIC/III, DmelGluRIIC, DGluRIIC, CG4226, DGluR-IIC, common type III glutamate receptor subunit, essential glutamate receptor subunit III, CT13021, glutamate receptor, DGluRIII, GluRIII, glutamate receptor subunit III, GluR3, GluR, GlutRIII, glutamate receptor IIC, glutamate receptor III, GluRII-C" "IPR028082=Periplasmic binding protein-like I, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor, IPR001508=Ionotropic glutamate receptor, metazoa, IPR001828=Receptor, ligand binding region" CG4226 16-Dec-15 2015_12 "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,paralytic,viable,lethal" "neuromuscular junction | larval stageast1), with GluRIICUAS.cMa, [-],neuromuscular junction | larval stage, with GluRIIC1/Df(2L)ast1, [-],neuromuscular junction | larval stage, with Df(2L)ast1/GluRIIC2, [-]" FBgn0065675 l(2)SH0676 lethal (2) SH0676 http://flybase.net/reports/FBgn0065675.html gene l(2)SH2 0676 16-Dec-15 2015_12 "lethal,recessive" FBgn0051523 CG31523 http://flybase.net/reports/FBgn0051523.html "FBan0031523, FBgn0037253" protein_coding_gene 0009922=fatty acid elongase activity "0006633=fatty acid biosynthetic process, 0000038=very long-chain fatty acid metabolic process, 0030497=fatty acid elongation" 0016021=integral component of membrane CG9798 IPR002076=ELO family CG31523 16-Dec-15 2015_12 "ENSDARG00000005785(elovl7b),ENSDARG00000069279(elovl7a),ENSDARG00000058356(elovl1b),ENSDARG00000002412(elovl1a)" "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "ENSXETG00000009581(ELOVL1),ENSXETG00000016688(elovl7)" "ENSMUSG00000021696(Elovl7),ENSMUSG00000006390(Elovl1)" "ENSG00000164181(ELOVL7),ENSG00000066322(ELOVL1)" "partially lethal - majority die,some die during pupal stage" DRSC12337 I 1.895548981 1.058865803 1.029693475 0.25967255 1.285461449 -1.193932646 FBgn0001915 l(2)25Bb lethal (2) 25Bb http://flybase.net/reports/FBgn0001915.html gene "l(2)jf11, jf11" 16-Dec-15 2015_12 lethal FBgn0031401 papi papi http://flybase.net/reports/FBgn0031401.html protein_coding_gene "0003723=RNA binding, 0005515=protein binding" 0043186=P granule "Partner of PIWIs, cg7082, CG7082, PAPI" "IPR004088=K Homology domain, type 1, IPR002999=Tudor domain, IPR004087=K Homology domain" CG7082 16-Dec-15 2015_12 ENSDARG00000053474(zgc:113056) ENSXETG00000019909(TDRKH) ENSMUSG00000041912(Tdrkh) ENSG00000182134(TDRKH) viable FBgn0036058 CG6707 http://flybase.net/reports/FBgn0036058.html protein_coding_gene "0034597=phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity" 0046856=phosphatidylinositol dephosphorylation "0005765=lysosomal membrane, 0031902=late endosome membrane" IPR019178=Transmembrane protein 55A/B CG6707 16-Dec-15 2015_12 "ENSDARG00000038615(zgc:123304),ENSDARG00000026387(tmem55bb),ENSDARG00000056034(tmem55a)" WBGene00022167(Y71H2AM.2) "ENSXETG00000017004(TMEM55B),ENSXETG00000014598(Q6DIE4_XENTR)" "ENSMUSG00000035953(Tmem55b),ENSMUSG00000028221(Tmem55a)" "ENSG00000165782(TMEM55B),ENSG00000155099(TMEM55A)" viable FBgn0037941 CG12594 http://flybase.net/reports/FBgn0037941.html protein_coding_gene "IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain" CG12594 16-Dec-15 2015_12 viable DRSC14532 E -0.387410235 1.284140811 1.694064556 0.305104892 0.188497943 -0.79491678 FBgn0020244 y5-5 y5-5 http://flybase.net/reports/FBgn0020244.html gene 16-Dec-15 2015_12 FBgn0037134 CG7407 http://flybase.net/reports/FBgn0037134.html FBgn0064922 protein_coding_gene BcDNA:LD29166 IPR026622=Matrix-remodeling-associated protein 7 CG7407 16-Dec-15 2015_12 viable FBgn0069997 BG01664 BG01664 http://flybase.net/reports/FBgn0069997.html gene 16-Dec-15 2015_12 stress response defective FBgn0022625 Dia7 Diaphorase 7 http://flybase.net/reports/FBgn0022625.html gene DIA-7 16-Dec-15 2015_12 FBgn0038847 CG12278 http://flybase.net/reports/FBgn0038847.html protein_coding_gene CG12278 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0003405 si3 ski 3 http://flybase.net/reports/FBgn0003405.html gene "si-3, ski-3" 16-Dec-15 2015_12 wild-type FBgn0040361 CG14627 http://flybase.net/reports/FBgn0040361.html FBgn0029564 protein_coding_gene EG:BACR42I17.5 CG14627 16-Dec-15 2015_12 FBgn0041740 l(2)DL1 lethal (2) DL1 http://flybase.net/reports/FBgn0041740.html gene 16-Dec-15 2015_12 lethal FBgn0039495 CG5909 http://flybase.net/reports/FBgn0039495.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP8, c-SP8" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP" CG5909 16-Dec-15 2015_12 viable FBgn0036278 CrzR Corazonin receptor http://flybase.net/reports/FBgn0036278.html "FBgn0046552, FBgn0046553" protein_coding_gene "0035237=corazonin receptor activity, 0008188=neuropeptide receptor activity, 0016500=protein-hormone receptor activity, 0004930=G-protein coupled receptor activity" "0071361=cellular response to ethanol, 0006117=acetaldehyde metabolic process, 0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0048149=behavioral response to ethanol" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "Corazonin receptor, CG10698, anon-WO0170980.196, DGRHRII, Drm-AKH receptor-2, crzR, Corazonin Receptor, anon-WO0170980.197, Crz-R, Drosophila Corazonin Receptor, Crz receptor, DCR, GRHRII, GRH-RII, GRHRII_Dro" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG10698 16-Dec-15 2015_12 "viable,fertile,chemical sensitive" DRSC09781 K 0.770601541 0.314764455 0.25783107 0.190026568 -1.57653305 -0.246825289 FBgn0005222 l(3)ET18 lethal Elaine Tasaka 18 http://flybase.net/reports/FBgn0005222.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0267897 CR46185 http://flybase.net/reports/FBgn0267897.html pseudogene_attribute CG12717-related CR46185 16-Dec-15 2015_12 FBgn0266464 Nsf2 N-ethylmaleimide-sensitive factor 2 http://flybase.net/reports/FBgn0266464.html "FBgn0264653, FBgn0013998, FBgn0053101" protein_coding_gene "0005524=ATP binding, 0016887=ATPase activity" "0006888=ER to Golgi vesicle-mediated transport, 0016082=synaptic vesicle priming, 0016192=vesicle-mediated transport, 0007269=neurotransmitter secretion, 0060439=trachea morphogenesis, 0007274=neuromuscular synaptic transmission, 0007430=terminal branching, open tracheal system, 0008582=regulation of synaptic growth at neuromuscular junction, 0006891=intra-Golgi vesicle-mediated transport, 0035494=SNARE complex disassembly" "0005737=cytoplasm, 0031201=SNARE complex" "N-ethylmaleimide sensitive factor 2, dNSF, Nsf-2, CG9931, EC3-11, dNSF-2, dNsf2, dNSF2, dnsf2, lotus, NSF2, CG33101, NSF-2, NEM-sensitive fusion protein 2, DmNSF2" "IPR004201=CDC48, domain 2, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR009010=Aspartate decarboxylase-like domain, IPR029067=CDC48 domain 2-like, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003338=CDC48, N-terminal subdomain" CG33101 16-Dec-15 2015_12 "ENSDARG00000007654(nsfa),ENSDARG00000038991(nsfb)" YBR080C(SEC18) WBGene00003818(nsf-1) ENSMUSG00000034187(Nsf) ENSG00000073969(NSF) " embryonic stage , larval stage , embryonic stage | stage 5,6 , embryonic stage | stage 8-10 , embryonic stage | stage 8-11 , embryonic stage && larval stage && adult stage , embryonic stage | stage >=14 " " embryonic/larval midgut

, dorsal mesothoracic disc

,

ubiquitous , posterior midgut proper primordium

, embryonic/larval hindgut

, mesoderm

, ectoderm

, anterior midgut proper primordium

, eye-antennal disc

, embryonic/larval salivary gland | restricted

, imaginal disc

, ring gland

, embryonic central nervous system

, ventral thoracic disc

" FBgn0267876 CR46164 http://flybase.net/reports/FBgn0267876.html pseudogene_attribute CG12717-related CR46164 16-Dec-15 2015_12 FBgn0019767 l(1)54B1 lethal (1) 54B1 http://flybase.net/reports/FBgn0019767.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053207 pxb pxb http://flybase.net/reports/FBgn0053207.html "FBgn0038352, FBgn0040562, FBgn0063689" protein_coding_gene "0048149=behavioral response to ethanol, 0007616=long-term memory, 0035207=negative regulation of hemocyte proliferation, 0002121=inter-male aggressive behavior, 0007611=learning or memory, 0007224=smoothened signaling pathway, 0016319=mushroom body development, 0008355=olfactory learning" "baikal, CG33207/Pxb, CG33207, paxillinB, BcDNA:RE16319, CG14873, Pxb, CG14874" CG33207 16-Dec-15 2015_12 "memory defective,chemical sensitive,behavior defective,recessive,viable,fertile" "macrochaeta,microchaeta & tarsal segment 5Dll-em212,microchaeta & tarsal segment 5ptc-559.1,anterior scutellar bristle,posterior scutellar bristle,microchaeta & tarsal segment 5hh-Gal4" DRSC14996 IEK 2.955291433 0.789206155 1.952390759 -0.3779634 -2.690729855 -0.708003824 FBgn0043486 l(2)05271b lethal (2) 05271b http://flybase.net/reports/FBgn0043486.html gene l(2)05271 16-Dec-15 2015_12 "lethal,recessive,visible" "leg,metathoracic tibia,metathoracic metatarsus" FBgn0011296 l(2)efl lethal (2) essential for life http://flybase.net/reports/FBgn0011296.html FBgn0011779 protein_coding_gene "0010506=regulation of autophagy, 0010998=regulation of translational initiation by eIF2 alpha phosphorylation, 0006497=protein lipidation" "Cryab, Lethal (2) essential for life, l(2)59Fa, l(2)13-1, el(2)13-1, lethal (2) essential for life, L(2)efl, l(2)Efl, CG4533, lethal(2)essential for life" "IPR031107=Small heat shock protein HSP20, IPR008978=HSP20-like chaperone, IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain" CG4533 16-Dec-15 2015_12 "ENSDARG00000053502(cryaa),ENSDARG00000042621(cryaba)" WBGene00021943(Y55F3BR.6) ENSXETG00000008972(HSPB1) "ENSMUSG00000032060(Cryab),ENSMUSG00000024041(Cryaa),ENSMUSG00000036854(Hspb6)" "ENSG00000109846(CRYAB),ENSG00000160202(CRYAA),ENSG00000004776(HSPB6)" " embryonic stage , embryonic stage -- adult stage " "long lived,viable" FBgn0013513 l(1)14Ai lethal (1) 14Ai http://flybase.net/reports/FBgn0013513.html gene "l(1)13Fl, XII, mn4, l(1)XII" 16-Dec-15 2015_12 "lethal,recessive" FBgn0083120 Uhg8 Uhg8 http://flybase.net/reports/FBgn0083120.html FBgn0259931 non_protein_coding_gene "dUhg8, CR42454, dUhg-like 8" CR42454 16-Dec-15 2015_12 FBgn0003064 anon-Pen79B anon-Pen79B http://flybase.net/reports/FBgn0003064.html gene "pen79B, GCR-21, Pen79B, GCR21" 16-Dec-15 2015_12 FBgn0265046 CG44163 http://flybase.net/reports/FBgn0265046.html protein_coding_gene CG44163 16-Dec-15 2015_12 FBgn0051163 SKIP Shal K+ channel interacting protein http://flybase.net/reports/FBgn0051163.html "FBgn0038933, FBgn0038935, FBgn0038936, FBgn0038937, FBgn0040583" protein_coding_gene 0005070=SH3/SH2 adaptor activity 0007608=sensory perception of smell "CG31163, CG13864, Shal K[+] Channel Interacting Protein, Skal K[+] channel interacting protein, CG7087, CG7086, CG5736, CG13863" "IPR011511=Variant SH3 domain, IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR001452=SH3 domain" CG31163 16-Dec-15 2015_12 "viable,fertile,smell perception defective" DRSC15864 I -1.750174428 0.789425996 -0.062565163 -0.162429267 -0.027969354 0.783927083 FBgn0032858 CG10949 http://flybase.net/reports/FBgn0032858.html protein_coding_gene 0003677=DNA binding "38C.46, FBgn0032858" "IPR017956=AT hook, DNA-binding motif, IPR006578=MADF domain" CG10949 16-Dec-15 2015_12 viable FBgn0260643 CG42535 http://flybase.net/reports/FBgn0260643.html protein_coding_gene CG42535 16-Dec-15 2015_12 FBgn0065948 l(2)SH0090 lethal (2) SH0090 http://flybase.net/reports/FBgn0065948.html gene l(2)SH2 0090 16-Dec-15 2015_12 "lethal,recessive" FBgn0032139 CG13116 http://flybase.net/reports/FBgn0032139.html protein_coding_gene CG13116 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" DRSC21945 IE 0.619769892 -1.815696396 -0.848566099 -2.862823447 0.583884643 -0.097195337 FBgn0082623 S(CycEJP)42S12 S(CycEJP)42S12 http://flybase.net/reports/FBgn0082623.html gene 42S12 16-Dec-15 2015_12 "lethal,recessive" FBgn0065358 l(2)SH1751 lethal (2) SH1751 http://flybase.net/reports/FBgn0065358.html gene l(2)SH2 1751 16-Dec-15 2015_12 "lethal,recessive" FBgn0025830 IntS8 Integrator 8 http://flybase.net/reports/FBgn0025830.html protein_coding_gene "0034472=snRNA 3'-end processing, 0016180=snRNA processing" 0032039=integrator complex "Int8, CG5859, EG:EG0003.5" CG5859 16-Dec-15 2015_12 ENSDARG00000057986(zgc:111823) ENSXETG00000006666(INTS8) ENSMUSG00000040738(Ints8) ENSG00000164941(INTS8) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC07417 I 0.250661945 -1.588239826 0.496869529 -0.036288503 -1.254237386 -0.4438577 FBgn0025727 tra::tra2 tra::tra2 http://flybase.net/reports/FBgn0025727.html engineered_fusion_gene TRA-2/TRA 16-Dec-15 2015_12 FBgn0010950 l(3)j00015 lethal (3) j00015 http://flybase.net/reports/FBgn0010950.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035594 CG4597 http://flybase.net/reports/FBgn0035594.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG4597 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0264483 CR43891 http://flybase.net/reports/FBgn0264483.html non_protein_coding_gene CR43891 16-Dec-15 2015_12 FBgn0065089 snmRNA:637 small non-messenger RNA 637 http://flybase.net/reports/FBgn0065089.html non_protein_coding_gene Dm-637 16-Dec-15 2015_12 FBgn0266473 walnut http://flybase.net/reports/FBgn0266473.html gene 16-Dec-15 2015_12 lethal FBgn0069237 gl(1)82-33 gl(1)82-33 http://flybase.net/reports/FBgn0069237.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryo,germline clone,maternal effect,posterior" FBgn0262120 l(2)L10 http://flybase.net/reports/FBgn0262120.html gene 16-Dec-15 2015_12 lethal FBgn0263042 CG43337 http://flybase.net/reports/FBgn0263042.html "FBgn0052345, FBgn0046990" protein_coding_gene "BcDNA:SD03580, CG32345" CG43337 16-Dec-15 2015_12 FBgn0034271 CG4996 http://flybase.net/reports/FBgn0034271.html protein_coding_gene "IPR019514=Protein of unknown function DUF2451, C-terminal, IPR019515=Vacuolar protein sorting-associated protein 54" CG4996 16-Dec-15 2015_12 ENSDARG00000002880(si:ch211-287b5.1) WBGene00008078(C44B9.1) ENSMUSG00000001376(Ccdc132) ENSG00000004766(CCDC132) viable FBgn0260074 2L3948 http://flybase.net/reports/FBgn0260074.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0001013 fs(3)A4 female sterile (3) A4 http://flybase.net/reports/FBgn0001013.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0027989 l(3)S127416 lethal (3) S127416 http://flybase.net/reports/FBgn0027989.html gene 1274/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0264402 FCG-E http://flybase.net/reports/FBgn0264402.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0034082 CG10734 http://flybase.net/reports/FBgn0034082.html protein_coding_gene CG10734 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0036204 Tim13 Tim13 http://flybase.net/reports/FBgn0036204.html protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0015031=protein transport, 0006626=protein targeting to mitochondrion" 0005744=mitochondrial inner membrane presequence translocase complex CG11611 IPR004217=Tim10/DDP family zinc finger CG11611 16-Dec-15 2015_12 ENSDARG00000058297(zgc:92895) YGR181W(TIM13) WBGene00006574(tin-13) ENSXETG00000001794(timm13a) ENSMUSG00000020219(Timm13) ENSG00000099800(TIMM13) viable FBgn0051001 CG31001 http://flybase.net/reports/FBgn0051001.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060891 l(3)S044623b lethal (3) S044623b http://flybase.net/reports/FBgn0060891.html gene 0446/23 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033464 CG1441 http://flybase.net/reports/FBgn0033464.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "IPR013120=Male sterility, NAD-binding, IPR016040=NAD(P)-binding domain, IPR026055=Fatty acyl-CoA reductase" CG1441 16-Dec-15 2015_12 "viable,fertile" DRSC06448 K 0.136227607 0.358566588 0.754044127 0.33330933 -0.402207443 -1.607116479 FBgn0260045 33R11 http://flybase.net/reports/FBgn0260045.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0030400 CG11138 http://flybase.net/reports/FBgn0030400.html "FBgn0030401, FBgn0061396, FBgn0063366" protein_coding_gene 0005654=nucleoplasm "RE18684, EP(X)1313, BcDNA:RE48052, CG1855, BEST:RE18684" "IPR022750=Interferon regulatory factor 2-binding protein 1 & 2, zinc finger, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG11138 16-Dec-15 2015_12 "ENSDARG00000005468(si:dkey-223n17.3),ENSDARG00000004297,ENSDARG00000006275(irf2bp2),ENSDARG00000004702(zgc:56251)" WBGene00010867(tag-260) ENSXETG00000011067(C14orf4) "ENSMUSG00000034168(6430527G18Rik),ENSMUSG00000044030(Irf2bp1)" "ENSG00000170604(IRF2BP1),ENSG00000119669(IRF2BPL)" viable FBgn0033960 CG10151 http://flybase.net/reports/FBgn0033960.html protein_coding_gene CG10151 16-Dec-15 2015_12 viable FBgn0058381 CG40381 http://flybase.net/reports/FBgn0058381.html FBan0040381 protein_coding_gene 16-Dec-15 2015_12 FBgn0061171 l(1)11Ba lethal (1) 11Ba http://flybase.net/reports/FBgn0061171.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265667 CR44474 http://flybase.net/reports/FBgn0265667.html non_protein_coding_gene CR44474 16-Dec-15 2015_12 FBgn0032898 CR9337 http://flybase.net/reports/FBgn0032898.html "FBpp0080977, FBgn0063270" pseudogene_attribute "CG9337, cg9337, BcDNA:GH05725" CR9337 16-Dec-15 2015_12 FBgn0000202 bo bordeaux http://flybase.net/reports/FBgn0000202.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective" "Malpighian tubule,pigment cell" FBgn0040988 CG15146 http://flybase.net/reports/FBgn0040988.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028561 sut3 sugar transporter 3 http://flybase.net/reports/FBgn0028561.html FBgn0033256 protein_coding_gene "0005351=sugar:proton symporter activity, 0005355=glucose transmembrane transporter activity" 0055085=transmembrane transport 0016021=integral component of membrane CG17976 "IPR003663=Sugar/inositol transporter, IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG17976 16-Dec-15 2015_12 YNL318C(HXT14) viable FBgn0032467 CG9934 http://flybase.net/reports/FBgn0032467.html protein_coding_gene 0034450=ubiquitin-ubiquitin ligase activity "0006511=ubiquitin-dependent protein catabolic process, 0016567=protein ubiquitination" 0000151=ubiquitin ligase complex "UBE4B, E4 B, ufd2, NM 135753.2, dUfd2, CG 9934, UFD2b" "IPR003613=U box domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019474=Ubiquitin conjugation factor E4, core" CG9934 16-Dec-15 2015_12 ENSDARG00000037017(ube4b) YDL190C(UFD2) WBGene00006734(ufd-2) ENSXETG00000022157(UBE4B) ENSMUSG00000028960(Ube4b) ENSG00000130939(UBE4B) viable FBgn0266135 c282 http://flybase.net/reports/FBgn0266135.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0033449 CG1663 http://flybase.net/reports/FBgn0033449.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1663 16-Dec-15 2015_12 WBGene00003909(pag-3) viable FBgn0002078 l(2)49Fg lethal (2) 49Fg http://flybase.net/reports/FBgn0002078.html gene "l(2)vr11, vr-11, vr11" 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation,dominant" FBgn0041231 Gr68a Gustatory receptor 68a http://flybase.net/reports/FBgn0041231.html FBgn0036201 protein_coding_gene 0008527=taste receptor activity "0019236=response to pheromone, 0016544=male courtship behavior, tapping to detect pheromone, 0050909=sensory perception of taste" 0016021=integral component of membrane "CG7303, GR68D.1, GR68a, Gr68D1, Gustatory receptor 68D.1, 68D.1" IPR013604=7TM chemoreceptor CG7303 16-Dec-15 2015_12 viable FBgn0266049 CR44814 http://flybase.net/reports/FBgn0266049.html non_protein_coding_gene CR44814 16-Dec-15 2015_12 FBgn0058162 CG40162 http://flybase.net/reports/FBgn0058162.html FBan0040162 protein_coding_gene 16-Dec-15 2015_12 DRSC20863 K 0.18125047 0.275146943 0.043751431 0.291621965 -1.712952325 -0.521284529 FBgn0043889 l(3)C416 lethal (3) C416 http://flybase.net/reports/FBgn0043889.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 "lethal,recessive" FBgn0259862 Su(Ste):CR42431 Su(Ste):CR42431 http://flybase.net/reports/FBgn0259862.html non_protein_coding_gene CR42431 CR42431 16-Dec-15 2015_12 FBgn0260453 CG17140 http://flybase.net/reports/FBgn0260453.html "FBgn0032306, FBgn0032307, FBgn0051722" protein_coding_gene "0008308=voltage-gated anion channel activity, 0015267=channel activity" "0055085=transmembrane transport, 0006820=anion transport" 0005741=mitochondrial outer membrane "CG31722-B, CG31722" "IPR027246=Eukaryotic porin/Tom40, IPR023614=Porin domain" CG17140 16-Dec-15 2015_12 FBgn0034553 CG9993 http://flybase.net/reports/FBgn0034553.html protein_coding_gene 0016207=4-coumarate-CoA ligase activity 0008152=metabolic process "IPR000873=AMP-dependent synthetase/ligase, IPR025110=AMP-binding enzyme C-terminal domain" CG9993 16-Dec-15 2015_12 viable FBgn0034274 CG10931 http://flybase.net/reports/FBgn0034274.html protein_coding_gene "IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG10931 16-Dec-15 2015_12 YBR175W(SWD3) FBgn0028058 l(3)S094003 lethal (3) S094003 http://flybase.net/reports/FBgn0028058.html gene 0940/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0024537 l(3)L1459 lethal (3) L1459 http://flybase.net/reports/FBgn0024537.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037722 CG8319 http://flybase.net/reports/FBgn0037722.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG8319 16-Dec-15 2015_12 WBGene00006970(zag-1) viable FBgn0030983 CG15882 http://flybase.net/reports/FBgn0030983.html protein_coding_gene CG15882 16-Dec-15 2015_12 viable FBgn0084232 W54 W54 http://flybase.net/reports/FBgn0084232.html gene 16-Dec-15 2015_12 visible eye FBgn0004704 l(2)56Ff lethal (2) 56Ff http://flybase.net/reports/FBgn0004704.html gene l(2)56F 16-Dec-15 2015_12 lethal FBgn0034899 CG13560 http://flybase.net/reports/FBgn0034899.html protein_coding_gene CG13560 16-Dec-15 2015_12 DRSC27479 K 0.578180783 1.142226968 0.556637907 0.873109496 1.5586713 0.601167478 FBgn0259851 Su(Ste):CR42420 Su(Ste):CR42420 http://flybase.net/reports/FBgn0259851.html non_protein_coding_gene CR42420 CR42420 16-Dec-15 2015_12 FBgn0041574 CG14599 http://flybase.net/reports/FBgn0041574.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267292 CR45728 http://flybase.net/reports/FBgn0267292.html non_protein_coding_gene CR45728 16-Dec-15 2015_12 FBgn0041748 l(1)em1 lethal (1) em1 http://flybase.net/reports/FBgn0041748.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053836 His3:CG33836 His3:CG33836 http://flybase.net/reports/FBgn0053836.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33836 "IPR000164=Histone H3/CENP-A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33836 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0037810 sle slender lobes http://flybase.net/reports/FBgn0037810.html protein_coding_gene "0007000=nucleolus organization, 0007420=brain development" "0005819=spindle, 0005634=nucleus, 0005730=nucleolus, 0005875=microtubule associated complex" "FBtr0082231, CG12819, SLE, slender lobe, CG12819-PA" CG12819 16-Dec-15 2015_12 "viable,sterile,recessive,developmental rate defective,neuroanatomy defective" "mushroom body alpha-lobe,mushroom body beta-lobe,neuroblast,nucleolus,adult mushroom body,mushroom body,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,gamma Kenyon cell" FBgn0266254 CR44949 http://flybase.net/reports/FBgn0266254.html non_protein_coding_gene lincRNA.854 CR44949 16-Dec-15 2015_12 FBgn0031232 CG11617 http://flybase.net/reports/FBgn0031232.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis" 0005634=nucleus Mkx "IPR001356=Homeobox domain, IPR008422=Homeobox KN domain, IPR009057=Homeodomain-like" CG11617 16-Dec-15 2015_12 ENSXETG00000004554(MKX) ENSMUSG00000061013(Mkx) ENSG00000150051(MKX) "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC00321 K 0.038619912 -0.131914706 -0.32808887 0.276053515 0.284158396 -1.664058312 FBgn0002784 Mosaic Mosaic http://flybase.net/reports/FBgn0002784.html gene Mos 16-Dec-15 2015_12 "visible,dominant" "dorsocentral bristle,scutellar bristle,adult thorax & macrochaeta" FBgn0035971 CG4477 http://flybase.net/reports/FBgn0035971.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0048190=wing disc dorsal/ventral pattern formation" "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG4477 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0267736 CR46067 http://flybase.net/reports/FBgn0267736.html non_protein_coding_gene Mgn99916 CR46067 16-Dec-15 2015_12 FBgn0011453 l(3)neo9 lethal (3) neo9 http://flybase.net/reports/FBgn0011453.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033601 Cpr47Ed Cuticular protein 47Ed http://flybase.net/reports/FBgn0033601.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG9076, DmelCpr47Ed" IPR000618=Insect cuticle protein CG9076 16-Dec-15 2015_12 viable FBgn0065609 l(2)SH0840 lethal (2) SH0840 http://flybase.net/reports/FBgn0065609.html gene l(2)SH2 0840 16-Dec-15 2015_12 "lethal,recessive" FBgn0262839 CG43203 http://flybase.net/reports/FBgn0262839.html protein_coding_gene "CG42793, noncoding_17732" CG43203 16-Dec-15 2015_12 FBgn0040683 CG14663 http://flybase.net/reports/FBgn0040683.html protein_coding_gene 16-Dec-15 2015_12 FBgn0264496 CR43898 http://flybase.net/reports/FBgn0264496.html non_protein_coding_gene CR43898 16-Dec-15 2015_12 FBgn0030384 CG2577 http://flybase.net/reports/FBgn0030384.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0022008=neurogenesis, 0006468=protein phosphorylation" "0005634=nucleus, 0005737=cytoplasm" CKIa-like "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG2577 16-Dec-15 2015_12 "viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0003378 Sgs8 Salivary gland secretion 8 http://flybase.net/reports/FBgn0003378.html protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "68C GII, Sgs-8, Sgs, CG6132, sgs8, group II, sgs-8, Gene II" CG6132 16-Dec-15 2015_12 larval stage | third instar salivary gland

"lethal,viable" embryonic/larval brain FBgn0029686 CG2941 http://flybase.net/reports/FBgn0029686.html protein_coding_gene CG2941 16-Dec-15 2015_12 FBgn0250839 CG2016 http://flybase.net/reports/FBgn0250839.html "FBgn0037289, FBgn0066915" protein_coding_gene 0005615=extracellular space anon-SAGE:Wang-083 IPR010562=Haemolymph juvenile hormone binding CG2016 16-Dec-15 2015_12 FBgn0260259 GSd329 http://flybase.net/reports/FBgn0260259.html gene 16-Dec-15 2015_12 lethal FBgn0259655 B0929 http://flybase.net/reports/FBgn0259655.html gene 16-Dec-15 2015_12 visible "wing vein,submarginal cell,wing cell,wing" FBgn0085603 CG41297 http://flybase.net/reports/FBgn0085603.html FBan0041297 protein_coding_gene 16-Dec-15 2015_12 FBgn0014281 l(3)3h lethal (3) 3h http://flybase.net/reports/FBgn0014281.html gene l(3L)3h 16-Dec-15 2015_12 FBgn0265155 CR44224 http://flybase.net/reports/FBgn0265155.html non_protein_coding_gene CR44224 16-Dec-15 2015_12 FBgn0262181 mir-972 mir-972 stem loop http://flybase.net/reports/FBgn0262181.html miRNA_gene "CR42888, miR-972, dme-mir-972" CR42888 16-Dec-15 2015_12 viable FBgn0259170 ë±-Man-Ia ë±-Mannosidase class I a http://flybase.net/reports/FBgn0259170.html "FBgn0010338, FBgn0042224, FBgn0052684, FBgn0052682" protein_coding_gene "0005509=calcium ion binding, 0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity" "0006487=protein N-linked glycosylation, 0035010=encapsulation of foreign target, 0072347=response to anesthetic, 0008340=determination of adult lifespan" "0005794=Golgi apparatus, 0016020=membrane, 0012505=endomembrane system, 0000139=Golgi membrane" "mas1, ManI, Man'ase, alpha-1,2-mannosidase I, alpha-Man-I, mas-1, alpha 1,2 mannosidase, CG32682, CG42275, alpha-Man-Ia, alpha-D-mannosidase, CG32684, alpha Mannosidase I, dManI, alpha-Man-l, alpha-Mannosidase class I a, Mannosidase 1, MA12, MAN-1, dMas-1, CG17809, CG18799, alpha-mannosidase, DM-GI" "IPR001382=Glycoside hydrolase, family 47" CG42275 16-Dec-15 2015_12 "ENSDARG00000041728(wu:fj20e02),ENSDARG00000005652(si:dkey-164k19.1)" WBGene00008411(D2030.1) ENSXETG00000009907(MAN1A2) "ENSMUSG00000008763(Man1a2),ENSMUSG00000003746(Man1a),ENSMUSG00000037306(Man1c1)" "ENSG00000198162(MAN1A2),ENSG00000111885(MAN1A1),ENSG00000117643(MAN1C1)" " adult stage , embryonic stage | late , pupal stage | late , embryonic stage | 0-3hr , embryonic stage | mid-late , embryonic stage | early , embryonic stage -- adult stage , embryonic stage | stage 14 " " adult head

, larval muscle system

, embryonic central nervous system | presumptive

, tracheal system

" FBgn0052579 CG32579 http://flybase.net/reports/FBgn0052579.html FBgn0030741 protein_coding_gene IPR018629=Transport protein XK CG32579 16-Dec-15 2015_12 "ENSDARG00000043410(xkr6),ENSDARG00000020443,ENSDARG00000036952(zgc:198371),ENSDARG00000026333(zgc:123037),ENSDARG00000019080(zgc:123035),ENSDARG00000039996(zgc:103514)" WBGene00000422(ced-8) ENSXETG00000000686(Q49M64_XENTR) "ENSMUSG00000042631(Xkr7),ENSMUSG00000051951(Xkr4),ENSMUSG00000037752(Xkr8)" "ENSG00000101321(XKR7),ENSG00000206579(XKR4),ENSG00000221947(XKR9)" "viable,fertile" FBgn0036684 CG3764 http://flybase.net/reports/FBgn0036684.html protein_coding_gene "IPR026156=Folliculin-interacting protein family, IPR028084=Folliculin-interacting protein, N-terminal domain, IPR028085=Folliculin-interacting protein, middle domain, IPR028086=Folliculin-interacting protein, C-terminal domain" CG3764 16-Dec-15 2015_12 WBGene00020208(T04C4.1) "ENSXETG00000016597(),ENSXETG00000012011(FNIP2)" "ENSMUSG00000035992(Fnip1),ENSMUSG00000061175" "ENSG00000217128(FNIP1),ENSG00000052795(FNIP2)" viable FBgn0261859 CG42788 http://flybase.net/reports/FBgn0261859.html "FBgn0051304, FBgn0038287, FBgn0038288, FBgn0061647, FBgn0038289" protein_coding_gene 0005856=cytoskeleton "anon-WO0118547.79, CG6960, CG18442, CG31304, CG6934" "IPR001202=WW domain, IPR019748=FERM central domain, IPR019749=Band 4.1 domain, IPR000299=FERM domain, IPR001478=PDZ domain, IPR029071=Ubiquitin-related domain" CG42788 16-Dec-15 2015_12 WBGene00001494(frm-8) ENSXETG00000005344(FRMPD4) "ENSMUSG00000042425(Frmpd3),ENSMUSG00000049176(Frmpd4)" "ENSG00000147234(FRMPD3),ENSG00000169933(FRMPD4)" FBgn0060580 l(3)S095108b lethal (3) S095108b http://flybase.net/reports/FBgn0060580.html gene 0951/08 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040733 CG15068 http://flybase.net/reports/FBgn0040733.html protein_coding_gene CT34939 IPR013172=Immune-induced protein Dim CG15068 16-Dec-15 2015_12 FBgn0260447 CR11386 http://flybase.net/reports/FBgn0260447.html FBgn0029973 pseudogene_attribute CG11386 CR11386 16-Dec-15 2015_12 "viable,fertile" FBgn0261837 pre-mod(mdg4)-T http://flybase.net/reports/FBgn0261837.html protein_coding_gene "Pre-MOD(MDG4)-T, CG42769" "IPR007588=Zinc finger, FLYWCH-type" CG42769 16-Dec-15 2015_12 FBgn0037086 CG7202 http://flybase.net/reports/FBgn0037086.html protein_coding_gene CG7202 16-Dec-15 2015_12 "viable,fertile" FBgn0000343 coi coitus interruptus http://flybase.net/reports/FBgn0000343.html gene 0007620=copulation 16-Dec-15 2015_12 "mating defective,male" spermatozoon FBgn0030033 CG1387 http://flybase.net/reports/FBgn0030033.html protein_coding_gene CG1387 16-Dec-15 2015_12 viable FBgn0041711 yellow-e yellow-e http://flybase.net/reports/FBgn0041711.html FBgn0038152 protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "e, yell-e, CG9792" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG9792 16-Dec-15 2015_12 "viable,fertile" FBgn0025181 fs(1)11-1505 fs(1)11-1505 http://flybase.net/reports/FBgn0025181.html gene 11-1505 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0060552 l(3)S097907b lethal (3) S097907b http://flybase.net/reports/FBgn0060552.html gene 0979/07 16-Dec-15 2015_12 lethal FBgn0005482 l(1)ts1299 lethal (1) ts1299 http://flybase.net/reports/FBgn0005482.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0262995 CR43303 http://flybase.net/reports/FBgn0262995.html non_protein_coding_gene CR43303 16-Dec-15 2015_12 FBgn0065133 l(3)SH127 lethal (3) SH127 http://flybase.net/reports/FBgn0065133.html gene l(2)SH3 127 16-Dec-15 2015_12 "lethal,recessive" FBgn0036984 CG13248 http://flybase.net/reports/FBgn0036984.html protein_coding_gene "0015174=basic amino acid transmembrane transporter activity, 0015171=amino acid transmembrane transporter activity" 0003333=amino acid transmembrane transport 0016020=membrane CAT-4 "IPR002293=Amino acid/polyamine transporter I, IPR029485=Cationic amino acid transporter, C-terminal" CG13248 16-Dec-15 2015_12 ENSDARG00000068286(LOC100332290) "YEL063C(CAN1),YFL055W(AGP3),YBR069C(TAT1),YNL270C(ALP1),YNL268W(LYP1),YDR508C(GNP1),YCL025C(AGP1),YDR046C(BAP3),YBR068C(BAP2),YKR039W(GAP1),YOL020W(TAT2),YGR191W(HIP1),YPL274W(SAM3),YPL265W(DIP5),YLL061W(MMP1),YOR348C(PUT4),YBR132C(AGP2),YDR160W(SSY1)" "WBGene00016806(C50D2.2),WBGene00017747(F23F1.6),WBGene00015197(B0454.6)" ENSXETG00000021616(SLC7A4) ENSG00000099960(SLC7A4) viable FBgn0043976 Su(tor)337-73 Su(tor)337-73 http://flybase.net/reports/FBgn0043976.html gene 337-73 16-Dec-15 2015_12 FBgn0085736 CG40472 http://flybase.net/reports/FBgn0085736.html "FBan0040472, FBgn0058472" protein_coding_gene 0005747=mitochondrial respiratory chain complex I CR40472 IPR026627=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 CG40472 16-Dec-15 2015_12 FBgn0031472 CG2983 http://flybase.net/reports/FBgn0031472.html protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" 0016020=membrane dC1GalT8 IPR003378=Fringe-like CG2983 16-Dec-15 2015_12 viable FBgn0261583 CG42693 http://flybase.net/reports/FBgn0261583.html protein_coding_gene CG42693 16-Dec-15 2015_12 FBgn0001744 l(1)HM14 lethal (1) HM14 http://flybase.net/reports/FBgn0001744.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0262587 CG43124 http://flybase.net/reports/FBgn0262587.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG43124 16-Dec-15 2015_12 FBgn0259249 EP-63 http://flybase.net/reports/FBgn0259249.html gene 16-Dec-15 2015_12 visible wing vein FBgn0038874 ETHR ETHR http://flybase.net/reports/FBgn0038874.html "FBgn0046538, FBgn0046539" protein_coding_gene "0042654=ecdysis-triggering hormone receptor activity, 0008227=G-protein coupled amine receptor activity, 0008528=G-protein coupled peptide receptor activity, 0008188=neuropeptide receptor activity, 0004997=thyrotropin-releasing hormone receptor activity" "0048812=neuron projection morphogenesis, 0022008=neurogenesis, 0009755=hormone-mediated signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "Dm ETHRa, anon-WO0170980.37, CG5911a, CG5911, Ecdysis triggering hormone receptor, CG5911b, ETH receptor, anon-WO0170980.38" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR002120=Thyrotropin-releasing hormone receptor" CG5911 16-Dec-15 2015_12 "ENSDARG00000036159(LOC569382),ENSDARG00000007121(LOC100331488),ENSDARG00000069055(si:ch211-187i23.1),ENSDARG00000032604,ENSDARG00000058599" "ENSXETG00000001766(),ENSXETG00000010499(TRHR),ENSXETG00000023989()" "ENSMUSG00000038760(Trhr),ENSMUSG00000039079(Trhr2)" ENSG00000174417(TRHR) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0029975 CG1444 http://flybase.net/reports/FBgn0029975.html protein_coding_gene 0016229=steroid dehydrogenase activity 0008152=metabolic process KAR "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG1444 16-Dec-15 2015_12 "ENSDARG00000035872(hsd17b12b),ENSDARG00000015709(hsd17b12a)" YBR159W(IFA38) "WBGene00002891(let-767),WBGene00007364(stdh-3),WBGene00007363(stdh-1),WBGene00008678(stdh-2),WBGene00006435(stdh-4)" ENSXETG00000022229(hsd17b12) ENSMUSG00000027195(Hsd17b12) ENSG00000149084(HSD17B12) "viable,fertile,some die during larval stage" embryonic/larval tracheal system | larval stage FBgn0037594 Or85d Odorant receptor 85d http://flybase.net/reports/FBgn0037594.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0032590=dendrite membrane, 0016021=integral component of membrane" "85A.2, CG11742, DOR114, 85.2, 85d" "IPR004117=Olfactory receptor, Drosophila" CG11742 16-Dec-15 2015_12 "viable,fertile" FBgn0025507 l(2)59ABc lethal (2) 59ABc http://flybase.net/reports/FBgn0025507.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0038679 CG6040 http://flybase.net/reports/FBgn0038679.html protein_coding_gene CG6040 16-Dec-15 2015_12 "ENSMUSG00000074305(C230081A13Rik),ENSMUSG00000050271(D8Ertd82e)" "ENSG00000173517,ENSG00000182319(SGK223)" "viable,visible" "chaeta,supernumerary" FBgn0029171 Fas1::hh Fas1::hh http://flybase.net/reports/FBgn0029171.html engineered_fusion_gene 16-Dec-15 2015_12 "wing disc,anterior compartment" FBgn0085721 CG41614 http://flybase.net/reports/FBgn0085721.html FBan0041614 protein_coding_gene 16-Dec-15 2015_12 FBgn0028166 l(3)S030305 lethal (3) S030305 http://flybase.net/reports/FBgn0028166.html gene 0303/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0052201 CG32201 http://flybase.net/reports/FBgn0052201.html "FBgn0036797, FBgn0036798" protein_coding_gene "0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0016222=procollagen-proline 4-dioxygenase complex" "CG18230, CG13382" "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG32201 16-Dec-15 2015_12 viable FBgn0019793 l(1)11 lethal (1) 11 http://flybase.net/reports/FBgn0019793.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001760 l(1)M11 lethal (1) M11 http://flybase.net/reports/FBgn0001760.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051485 tRNA:CR31485:ë¬ transfer RNA:CR31485:pseudogene http://flybase.net/reports/FBgn0051485.html FBgn0060191 pseudogene_attribute "tRNA:KPsi:CTT:AE002699, AE002699.trna6-LysCTT, CR31485, chr3R.trna79-LysCTT" CR31485 16-Dec-15 2015_12 FBgn0038577 CG12321 http://flybase.net/reports/FBgn0038577.html protein_coding_gene 0000502=proteasome complex IPR019151=Proteasome assembly chaperone 2 CG12321 16-Dec-15 2015_12 ENSDARG00000035987(psmg2) ENSXETG00000019670(Q5XGC5_XENTR) ENSMUSG00000024537(Psmg2) ENSG00000128789(PSMG2) viable FBgn0034814 CG9890 http://flybase.net/reports/FBgn0034814.html FBgn0027743 protein_coding_gene 0046872=metal ion binding "ld46465, anon-EST:Posey169" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG9890 16-Dec-15 2015_12 ENSDARG00000025346(znf277) WBGene00009772(ztf-7) ENSXETG00000009253(ZNF277) ENSMUSG00000055917(Zfp277) ENSG00000198839(ZNF277) "viable,visible" "trichogen cell,mesothoracic tergum" DRSC25594 K -0.055749845 0.626669257 -1.378642256 1.398917848 -1.590052543 -1.323099221 FBgn0039538 CG12883 http://flybase.net/reports/FBgn0039538.html protein_coding_gene CG12883 16-Dec-15 2015_12 FBgn0261522 CR42657 http://flybase.net/reports/FBgn0261522.html non_protein_coding_gene CG42657 CR42657 16-Dec-15 2015_12 FBgn0039020 CG17141 http://flybase.net/reports/FBgn0039020.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0042254=ribosome biogenesis 0005739=mitochondrion "IPR023179=GTP-binding protein, orthogonal bundle domain, IPR016478=GTPase, MTG1, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006073=GTP binding domain, IPR030378=Circularly permuted (CP)-type guanine nucleotide-binding (G) domain" CG17141 16-Dec-15 2015_12 "ENSDARG00000027179,ENSDARG00000069386(gtpbpl)" YMR097C(MTG1) WBGene00022054(Y67D2.4) ENSXETG00000022149(MTG1) ENSMUSG00000039018(Mtg1) ENSG00000148824(MTG1) FBgn0037455 CG2336 http://flybase.net/reports/FBgn0037455.html protein_coding_gene "0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" 0055114=oxidation-reduction process "IPR016163=Aldehyde dehydrogenase, C-terminal, IPR016161=Aldehyde/histidinol dehydrogenase, IPR009961=Protein of unknown function DUF1487" CG2336 16-Dec-15 2015_12 viable FBgn0033845 mars mars http://flybase.net/reports/FBgn0033845.html protein_coding_gene "0008157=protein phosphatase 1 binding, 0008017=microtubule binding" "0007346=regulation of mitotic cell cycle, 0051382=kinetochore assembly, 0007059=chromosome segregation, 0051642=centrosome localization, 0043146=spindle stabilization, 0023052=signaling, 0043148=mitotic spindle stabilization, 0007052=mitotic spindle organization" "0005819=spindle, 0000922=spindle pole, 0005634=nucleus, 0005828=kinetochore microtubule, 0005654=nucleoplasm, 0005737=cytoplasm, 0005876=spindle microtubule, 0072686=mitotic spindle" "dhrp/gkap, gkap, Mars, HURP, CG17064, D-HURP" IPR005026=SAPAP family CG17064 16-Dec-15 2015_12 "ENSDARG00000060849,ENSDARG00000012823" ENSMUSG00000037544(Dlgap5) "mitotic cell cycle defective,chemical sensitive,viable,fertile,grandchildless,partially,conditional,lethal,temperature conditional,female sterile,visible,increased cell death,hatching behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical resistant,majority die during embryonic stage" "mitotic spindle,centrosome,centrosome | conditional | embryonic stage 4,nucleus | conditional | embryonic stage 4,spindle | conditional | embryonic stage 4,spindle pole | conditional | embryonic stage 4,spindle,egg,embryo,eye disc,eye,meiotic spindle,mitotic spindleda.G32,spindle poleda.G32,mitotic spindlemat.ë±Tub67C.THsimVP16,spindle polemat.ë±Tub67C.THsimVP16,centrosomemat.ë±Tub67C.THsimVP16,nucleusmat.ë±Tub67C.THsimVP16" FBgn0267317 CR45753 http://flybase.net/reports/FBgn0267317.html non_protein_coding_gene CR45753 16-Dec-15 2015_12 FBgn0267255 CG45691 http://flybase.net/reports/FBgn0267255.html protein_coding_gene lincRNA.169 CG45691 16-Dec-15 2015_12 FBgn0261386 Gpa2 Glycoprotein hormone alpha 2 ortholog (H. sapiens) http://flybase.net/reports/FBgn0261386.html "FBgn0083224, FBan0017878, FBgn0039947" protein_coding_gene "0005179=hormone activity, 0046982=protein heterodimerization activity, 0001664=G-protein coupled receptor binding" 0009755=hormone-mediated signaling pathway 0005615=extracellular space "Glycoprotein hormone alpha 2, GPA2, CG17878, gpa2, glycoprotein hormone alpha 2" "IPR029034=Cystine-knot cytokine, IPR006208=Glycoprotein hormone subunit beta, cystine knot" CG17878 16-Dec-15 2015_12 FBgn0259577 GG01286 http://flybase.net/reports/FBgn0259577.html gene 16-Dec-15 2015_12 visible "wing vein L3,distal,wing cell" FBgn0085194 CG34165 http://flybase.net/reports/FBgn0085194.html protein_coding_gene CG34165 16-Dec-15 2015_12 FBgn0020889 Su(osk)P2 Suppressor of oskar P2 http://flybase.net/reports/FBgn0020889.html gene P2 16-Dec-15 2015_12 FBgn0039927 CG11155 http://flybase.net/reports/FBgn0039927.html protein_coding_gene "0015277=kainate selective glutamate receptor activity, 0005234=extracellular-glutamate-gated ion channel activity" "0006811=ion transport, 0060025=regulation of synaptic activity, 0048812=neuron projection morphogenesis" 0005886=plasma membrane "DmelCG11155, CT30863" "IPR001508=Ionotropic glutamate receptor, metazoa, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I, IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG11155 16-Dec-15 2015_12 WBGene00001616(glr-5) ENSXETG00000017031(GRIK4) viable FBgn0052200 tRNA:CR32200 transfer RNA:CR32200 http://flybase.net/reports/FBgn0052200.html FBgn0060116 tRNA_gene 0033424=CCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:P:CGG:AE002602-b, CR32200, AE002602.trna26-ProCGG, chr3L.trna31-ProCGG" CR32200 16-Dec-15 2015_12 FBgn0033633 CG7759 http://flybase.net/reports/FBgn0033633.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression 0005737=cytoplasm "IPR002893=Zinc finger, MYND-type, IPR001214=SET domain, IPR011990=Tetratricopeptide-like helical domain" CG7759 16-Dec-15 2015_12 YHR207C(SET5) WBGene00007403(set-3) ENSXETG00000013541(SMYD4) ENSMUSG00000018809(Smyd4) ENSG00000186532(SMYD4) "viable,fertile" FBgn0061503 l(2)44Fm lethal (2) 44Fm http://flybase.net/reports/FBgn0061503.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029958 Pdp Pyruvate dehydrogenase phosphatase http://flybase.net/reports/FBgn0029958.html protein_coding_gene "0004741=[pyruvate dehydrogenase (lipoamide)] phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0004722=protein serine/threonine phosphatase activity" "0006470=protein dephosphorylation, 0006090=pyruvate metabolic process" "0005759=mitochondrial matrix, 0005739=mitochondrion, 0005634=nucleus, 0005737=cytoplasm" "pyruvate dehydrogenase phosphatase, CG12151, 153332_at, PDP, pdp" "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C" CG12151 16-Dec-15 2015_12 "ENSDARG00000058571(pdp2),ENSDARG00000062241(si:ch211-15p9.2)" YOR090C(PTC5) WBGene00022832(pdp-1) "ENSXETG00000025921(PDP1),ENSXETG00000017419(PDP2)" "ENSMUSG00000049225(Pdp1),ENSMUSG00000048371(Pdp2)" "ENSG00000164951(PDP1),ENSG00000172840(PDP2)" "viable,fertile,thermotaxis behavior defective" FBgn0053538 tRNA:CR33538 transfer RNA:CR33538 http://flybase.net/reports/FBgn0053538.html FBgn0060085 tRNA_gene "0033448=AGG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna41-ArgCCT, tRNA:R:CCT:AE002787-b, CR33538, AE002787.trna57-ArgCCT" CR33538 16-Dec-15 2015_12 FBgn0000689 flrdM flight reduced M http://flybase.net/reports/FBgn0000689.html gene 16-Dec-15 2015_12 "jumping defective,hypoactive,flight defective" FBgn0069241 fnu fnu http://flybase.net/reports/FBgn0069241.html gene "0008283=cell proliferation, 0042023=DNA endoreduplication" fat nuclei 16-Dec-15 2015_12 FBgn0086056 snoRNA:Me18S-A425 http://flybase.net/reports/FBgn0086056.html snoRNA_gene "Me18S-A425(Dm425), CR34685, Me18S-Am425, Dm425" CR34685 16-Dec-15 2015_12 FBgn0030503 Tango2 Transport and Golgi organization 2 http://flybase.net/reports/FBgn0030503.html protein_coding_gene "0007030=Golgi organization, 0009306=protein secretion" "0005829=cytosol, 0005794=Golgi apparatus" "TANGO2, CG11176" IPR008551=Transport and Golgi organisation protein 2 CG11176 16-Dec-15 2015_12 ENSDARG00000056550(zgc:100952) YGR127W() "WBGene00013587(Y80D3A.9),WBGene00011305(R186.1)" ENSXETG00000006319(BC075282.1) ENSMUSG00000013539(D16H22S680E) ENSG00000183597(C22orf25) viable FBgn0010762 simj simjang http://flybase.net/reports/FBgn0010762.html "FBgn0011360, FBgn0011522, FBgn0036097, FBgn0036098, FBgn0052067, FBgn0062069" protein_coding_gene 0005515=protein binding "0046959=habituation, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0060912=cardiac cell fate specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated" "0005634=nucleus, 0016581=NuRD complex" "dp66, unnamed, l(3)j4A5, p66, l(3)rN672, anon-WO0118547.361, CG32067, l(3)01814, SIMJ, CG8000, CG7983, p66/68-like" CG32067 16-Dec-15 2015_12 "ENSDARG00000006192(gatad2a),ENSDARG00000005834(si:dkeyp-66g8.1)" WBGene00000938(dcp-66) "ENSXETG00000019921(GATAD2B),ENSXETG00000013053(gatad2a)" "ENSMUSG00000036180(Gatad2a),ENSMUSG00000042390(Gatad2b)" "ENSG00000167491(GATAD2A),ENSG00000143614(GATAD2B)" "viable,fertile,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,melanotic necrosis,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage,learning defective,neuroanatomy defective" "cardioblast,leg,mesothoracic tergum,wing,pupal abdomen,heart primordium,metathoracic leg,scutellar bristle,supernumerary,embryonic/larval neuromuscular junction | third instar larval stage,presynaptic active zone, with Dcr-2UAS.cDa, elav.PU" FBgn0030594 CG9509 http://flybase.net/reports/FBgn0030594.html protein_coding_gene "0008812=choline dehydrogenase activity, 0016491=oxidoreductase activity, 0050660=flavin adenine dinucleotide binding" "0007498=mesoderm development, 0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process" Dm GMCbeta2 "IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG9509 16-Dec-15 2015_12 viable FBgn0005238 l(3)R70 lethal of Roberts 70 http://flybase.net/reports/FBgn0005238.html gene l(3)B70 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0042138 CG18815 http://flybase.net/reports/FBgn0042138.html FBgn0027720 protein_coding_gene 0052689=carboxylic ester hydrolase activity 0005737=cytoplasm "Acyl-protein Thioesterase 1, APT1, anon-EST:Posey232" "IPR029058=Alpha/Beta hydrolase fold, IPR003140=Phospholipase/carboxylesterase/thioesterase" CG18815 16-Dec-15 2015_12 "ENSDARG00000053656(zgc:73210),ENSDARG00000041337(lypla1)" YLR118C() WBGene00010564(ath-1) "ENSXETG00000008101(lypla1),ENSXETG00000025533(lypla2)" "ENSMUSG00000025903(Lypla1),ENSMUSG00000028670(Lypla2)" "ENSG00000120992(LYPLA1),ENSG00000011009(LYPLA2)" viable FBgn0250868 CG42239 http://flybase.net/reports/FBgn0250868.html protein_coding_gene CG42239 16-Dec-15 2015_12 FBgn0039734 Tace Tace http://flybase.net/reports/FBgn0039734.html protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" "0006508=proteolysis, 0006509=membrane protein ectodomain proteolysis" 0016021=integral component of membrane "CG7908, tumor necrosis factor-alpha-converting enzyme, TACE, DTACE, CT23908" "IPR024079=Metallopeptidase, catalytic domain, IPR001590=Peptidase M12B, ADAM/reprolysin, IPR002870=Peptidase M12B, propeptide, IPR001762=Disintegrin domain" CG7908 16-Dec-15 2015_12 "ENSDARG00000043213(adam17a),ENSDARG00000042540(adam17b)" WBGene00000075(adm-4) ENSXETG00000008262(ADAM17) ENSMUSG00000052593(Adam17) ENSG00000151694(ADAM17) "wild-type,viable" FBgn0061100 l(3)S009418 lethal (3) S009418 http://flybase.net/reports/FBgn0061100.html gene 0094/18 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011250 ms(3)72D male sterile (3) 72D http://flybase.net/reports/FBgn0011250.html gene 0007286=spermatid development "ms(3)03957, ry72D, ms(3)ry72D" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0265295 pncr014:3L http://flybase.net/reports/FBgn0265295.html "FBgn0046272, FBgn0053944, FBgn0262145" non_protein_coding_gene "BEST:LD13184, CR42871, CR33944, putative noncoding RNA 014:3L" CR42871 16-Dec-15 2015_12 FBgn0010195 x3 x3 http://flybase.net/reports/FBgn0010195.html gene 16-Dec-15 2015_12 FBgn0050487 CG30487 http://flybase.net/reports/FBgn0050487.html FBgn0045272 protein_coding_gene "NEST:bs16h04, bs33e02.y1" CG30487 16-Dec-15 2015_12 "viable,male fertile,female fertile" FBgn0259185 Ir60b Ionotropic receptor 60b http://flybase.net/reports/FBgn0259185.html "FBan0013582, FBgn0035015" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG13582, ionotropic receptor 60b, IR60b, DmelIR60b, CG42289" CG42289 16-Dec-15 2015_12 viable FBgn0043560 Su(hh)VII Su(hh)VII http://flybase.net/reports/FBgn0043560.html gene 16-Dec-15 2015_12 FBgn0037305 CG12173 http://flybase.net/reports/FBgn0037305.html protein_coding_gene "0000287=magnesium ion binding, 0043874=acireductone synthase activity" 0019509=L-methionine biosynthetic process from methylthioadenosine 24644163 "IPR027511=Enolase-phosphatase E1, eukaryotes, IPR006439=HAD hydrolase, subfamily IA, IPR023943=Enolase-phosphatase E1, IPR023214=HAD-like domain" CG12173 16-Dec-15 2015_12 ENSDARG00000026198(enoph1) YEL038W(UTR4) WBGene00010286(F58H1.3) ENSXETG00000012582(TTpA008k20.1) ENSMUSG00000029326(Enoph1) ENSG00000145293(ENOPH1) viable FBgn0002237 l(3)68Bd lethal (3) 68Bd http://flybase.net/reports/FBgn0002237.html gene "Complementation group F, l(3)C404, l(3)F, F" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible" macrochaeta FBgn0033359 CG8213 http://flybase.net/reports/FBgn0033359.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0098595=perivitelline space "c-SP44, SP44" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG8213 16-Dec-15 2015_12 "WBGene00006625(try-7),WBGene00006624(try-6)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0025468 tin::Drer\Nkx2.5 Nkx2.5 http://flybase.net/reports/FBgn0025468.html engineered_fusion_gene tin::Brer\Nkx2.5 16-Dec-15 2015_12 FBgn0262599 CG43129 http://flybase.net/reports/FBgn0262599.html "FBgn0032309, FBgn0032310" protein_coding_gene "CG17086, CG17085" IPR001214=SET domain CG43129 16-Dec-15 2015_12 FBgn0039022 CG4725 http://flybase.net/reports/FBgn0039022.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis 0005576=extracellular region "IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain" CG4725 16-Dec-15 2015_12 viable FBgn0086371 poly poly http://flybase.net/reports/FBgn0086371.html "FBgn0014374, FBgn0010858, FBgn0002506, FBgn0004732, FBgn0023020, FBgn0038141" protein_coding_gene 0005158=insulin receptor binding "0008286=insulin receptor signaling pathway, 0008103=oocyte microtubule cytoskeleton polarization, 0035011=melanotic encapsulation of foreign target" "lethal (3) 05137, l(3)05137, did, l(3)S008131, CG9829, 0081/31, did/alt1, unnamed" IPR018627=Elongation complex protein 6 CG9829 16-Dec-15 2015_12 ENSMUSG00000054836(2610002I17Rik) FBgn0033203 CG2070 http://flybase.net/reports/FBgn0033203.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG2070 16-Dec-15 2015_12 "ENSDARG00000045277(rdh12l),ENSDARG00000018069(rdh12),ENSDARG00000068474(si:dkey-94e7.2),ENSDARG00000058966(zgc:112332),ENSDARG00000071660,ENSDARG00000008491(LOC407663),ENSDARG00000054797(zgc:153441)" YOR246C() WBGene00000985(dhs-22) ENSXETG00000008385(rdh13) ENSMUSG00000008435(Rdh13) ENSG00000160439(RDH13) lethal FBgn0004964 l(1)17Cb lethal (1) 17Cb http://flybase.net/reports/FBgn0004964.html gene 13C 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004898 fd96Cb forkhead domain 96Cb http://flybase.net/reports/FBgn0004898.html protein_coding_gene "0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007389=pattern specification process, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0048813=dendrite morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0009888=tissue development, 0048806=genitalia development" "0005667=transcription factor complex, 0005634=nucleus" "fd5, CG11922, Dmfd5, FD5" "IPR018122=Fork head domain conserved site1, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain" CG11922 16-Dec-15 2015_12 "ENSDARG00000045569(foxb1.2),ENSDARG00000053650,ENSDARG00000069939,ENSDARG00000037475(LOC559714)" ENSXETG00000017708(FOXB1) "ENSMUSG00000059246(Foxb1),ENSMUSG00000056829(Foxb2)" "ENSG00000171956(FOXB1),ENSG00000204612(FOXB2)" embryonic stage " neuroblast

, sensory neuron

, embryonic peripheral nervous system

" viable FBgn0027648 l(2)CL-R lethal (2) Cell Lethal Right http://flybase.net/reports/FBgn0027648.html gene CL2R 16-Dec-15 2015_12 lethal FBgn0011559 Acp36DE Accessory gland protein 36DE http://flybase.net/reports/FBgn0011559.html FBgn0044574 protein_coding_gene 0005179=hormone activity "0046693=sperm storage, 0032504=multicellular organism reproduction, 0045434=negative regulation of female receptivity, post-mating, 0007321=sperm displacement, 0046692=sperm competition, 0042628=mating plug formation" "0005615=extracellular space, 0005576=extracellular region" "Acp36D, 36DE accessory gland protein, CT22109, anon-WO0140519.55, Accessory gland peptide 36DE, Acp, CG7157, Accessory gland protein" CG7157 16-Dec-15 2015_12 adult stage | male " male accessory gland main cell

, male accessory gland

" "male fertile,viable,male sterile,partially,recessive,lethal" "female reproductive system,uterus" FBgn0266859 CR45320 http://flybase.net/reports/FBgn0266859.html non_protein_coding_gene CR45320 16-Dec-15 2015_12 FBgn0033936 CG17386 http://flybase.net/reports/FBgn0033936.html protein_coding_gene 0000166=nucleotide binding CT33484 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006630=RNA-binding protein Lupus La, IPR024642=SUZ-C domain" CG17386 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0065577 l(2)SH0951 lethal (2) SH0951 http://flybase.net/reports/FBgn0065577.html gene l(2)SH2 0951 16-Dec-15 2015_12 "lethal,recessive" FBgn0267668 CR46006 http://flybase.net/reports/FBgn0267668.html "FBgn0266779, FBgn0265415" non_protein_coding_gene "CR44327, pri-mir-276b_mir-276a, CR45244" CR46006 16-Dec-15 2015_12 FBgn0065903 l(2)SH0197 lethal (2) SH0197 http://flybase.net/reports/FBgn0065903.html gene l(2)SH2 0197 16-Dec-15 2015_12 "lethal,recessive" FBgn0031850 Tsp Thrombospondin http://flybase.net/reports/FBgn0031850.html FBgn0029130 protein_coding_gene "0005509=calcium ion binding, 0008201=heparin binding" "0033627=cell adhesion mediated by integrin, 0016203=muscle attachment, 0007517=muscle organ development" "0031012=extracellular matrix, 0043234=protein complex, 0005927=muscle tendon junction, 0005576=extracellular region" "CG11326, DTSP, SP295, thrombospondin, tsp, D-TSP, CT31613" "IPR003367=Thrombospondin, type 3-like repeat, IPR024665=Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001881=EGF-like calcium-binding domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR017897=Thrombospondin, type 3 repeat, IPR008859=Thrombospondin, C-terminal, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR028974=TSP type-3 repeat, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG11326 16-Dec-15 2015_12 "ENSDARG00000029495(thbs3a),ENSDARG00000012060(thbs3b),ENSDARG00000020072(thbs4b),ENSDARG00000052631,ENSDARG00000053865(comp)" "ENSXETG00000000500(THBS4),ENSXETG00000011202(COMP)" "ENSMUSG00000031849(Comp),ENSMUSG00000021702(Thbs4),ENSMUSG00000028047(Thbs3)" "ENSG00000105664(COMP),ENSG00000113296(THBS4),ENSG00000169231(THBS3)" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval somatic muscle,embryonic/larval muscle system,tendon cell,muscle attachment site,lateral longitudinal muscle 1,ventral longitudinal muscle,dorsal oblique muscle,dorsal acute muscle" FBgn0085832 CR42205 http://flybase.net/reports/FBgn0085832.html FBan0042205 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0005290 mei-2185 meiotic 2185 http://flybase.net/reports/FBgn0005290.html gene 2185 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0065680 l(2)SH0669 lethal (2) SH0669 http://flybase.net/reports/FBgn0065680.html gene l(2)SH2 0669 16-Dec-15 2015_12 "lethal,recessive" FBgn0016082 ynd yande http://flybase.net/reports/FBgn0016082.html gene 16-Dec-15 2015_12 FBgn0264699 CG43968 http://flybase.net/reports/FBgn0264699.html protein_coding_gene lincRNA.665 CG43968 16-Dec-15 2015_12 FBgn0033300 CG14754 http://flybase.net/reports/FBgn0033300.html protein_coding_gene 16-Dec-15 2015_12 DRSC06489 K -0.116909718 0.354327169 -0.375000758 -0.203823896 0.742037203 1.679481032 FBgn0259464 EP-298 http://flybase.net/reports/FBgn0259464.html gene 16-Dec-15 2015_12 visible wing FBgn0038871 CG3337 http://flybase.net/reports/FBgn0038871.html protein_coding_gene mat1 "IPR026170=FAM173 family, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG3337 16-Dec-15 2015_12 ENSDARG00000033451(fam173b) WBGene00012658(Y39A1A.21) ENSXETG00000023151(FAM173B) ENSMUSG00000039065(Fam173b) ENSG00000150756(FAM173B) viable FBgn0036695 Papst2 PAPS transporter 2 http://flybase.net/reports/FBgn0036695.html protein_coding_gene 0046964=3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity "0015012=heparan sulfate proteoglycan biosynthetic process, 0055085=transmembrane transport" "0005783=endoplasmic reticulum, 0000137=Golgi cis cisterna" "dPAPST2, CG7853, PAPST2" IPR013657=UAA transporter CG7853 16-Dec-15 2015_12 ENSDARG00000045437(slc35b3) WBGene00018827(pst-2) ENSXETG00000020461(SLC35B3) ENSMUSG00000021432(Slc35b3) ENSG00000124786(SLC35B3) partially lethal - majority die FBgn0039954 CG17429 http://flybase.net/reports/FBgn0039954.html "FBgn0058065, FBan0017429" protein_coding_gene CG40065 16-Dec-15 2015_12 FBgn0028082 l(3)S085212 lethal (3) S085212 http://flybase.net/reports/FBgn0028082.html gene 0852/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0044323 Cka Connector of kinase to AP-1 http://flybase.net/reports/FBgn0044323.html "FBgn0010608, FBgn0010681, FBgn0026012, FBgn0031978, FBgn0046423, FBgn0046425, FBgn0046426, FBgn0046427" protein_coding_gene 0005515=protein binding "0046579=positive regulation of Ras protein signal transduction, 0046330=positive regulation of JNK cascade, 0042051=compound eye photoreceptor development, 0006909=phagocytosis, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007254=JNK cascade, 0042332=gravitaxis, 0051726=regulation of cell cycle, 0007391=dorsal closure" "0072686=mitotic spindle, 0005737=cytoplasm, 0005634=nucleus" "anon-WO0172774.175, CG7392, cka, CKA, 5836, Dcka, anon-WO0172774.177, anon-WO0172774.179, connector of kinase to AP-1, l(2)s1883, l(2)05836, WD-40-family-member, anon-WO0172774.174" "IPR020472=G-protein beta WD-40 repeat, IPR013258=Striatin, N-terminal, IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG7392 16-Dec-15 2015_12 ENSDARG00000001729(strn3) YMR029C(FAR8) WBGene00010631(cash-1) ENSXETG00000014156(STRN3) "ENSMUSG00000030374(Strn4),ENSMUSG00000020954(Strn3),ENSMUSG00000024077(Strn)" "ENSG00000090372(STRN4),ENSG00000196792(STRN3),ENSG00000115808(STRN)" "viable,fertile,lethal,recessive,fully,rescuable maternal effect,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,gravitaxis defective,visible" "imaginal disc,embryonic/first instar larval cuticle,dorsal,head,embryonic dorsal epidermis,germline clone,rescuable maternal effect,embryonic head,embryonic leading edge cell,maternal effect,tarsal segment,arista,third segment of antenna,wing,unguis,pulvillus" DRSC22858 I 0.384946579 -3.511340136 0.001923618 -0.032850192 0.413195443 -0.156517786 FBgn0053640 CG33640 http://flybase.net/reports/FBgn0053640.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33640 16-Dec-15 2015_12 FBgn0060440 l(3)S124310b lethal (3) S124310b http://flybase.net/reports/FBgn0060440.html gene 1243/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0029957 CG12155 http://flybase.net/reports/FBgn0029957.html protein_coding_gene IPR006578=MADF domain CG12155 16-Dec-15 2015_12 WBGene00015468(C05D2.6) viable FBgn0000505 dsx-c21C doublesex cognate 21C http://flybase.net/reports/FBgn0000505.html gene dsx-c21 16-Dec-15 2015_12 FBgn0259638 B1193 http://flybase.net/reports/FBgn0259638.html gene 16-Dec-15 2015_12 visible "wing vein,submarginal cell,anterior crossvein,tarsal segment,unguis,arista" FBgn0040358 CG14625 http://flybase.net/reports/FBgn0040358.html FBgn0029567 protein_coding_gene EG:BACR42I17.8 CG14625 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0030289 GCS1 Glucosidase 1 http://flybase.net/reports/FBgn0030289.html protein_coding_gene 0004573=mannosyl-oligosaccharide glucosidase activity 0009311=oligosaccharide metabolic process 0012505=endomembrane system CG1597 "IPR031335=Glycosyl hydrolase family 63, C-terminal, IPR004888=Glycoside hydrolase, family 63, IPR008928=Six-hairpin glycosidase-like" CG1597 16-Dec-15 2015_12 ENSDARG00000060252(mogs) YGL027C(CWH41) WBGene00008775(F13H10.4) ENSXETG00000002403(Q497D5_XENTR) ENSMUSG00000030036(Mogs) ENSG00000115275(MOGS) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039560 CG5514 http://flybase.net/reports/FBgn0039560.html protein_coding_gene CG5514 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0061120 l(3)S005029a lethal (3) S005029a http://flybase.net/reports/FBgn0061120.html gene 0050/29 16-Dec-15 2015_12 "lethal,recessive" FBgn0058302 CG40302 http://flybase.net/reports/FBgn0058302.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002283 l(3)73Ah lethal (3) 73Ah http://flybase.net/reports/FBgn0002283.html "FBgn0010783, FBgn0036644" protein_coding_gene 0008270=zinc ion binding 0005634=nucleus "l(3)133.18, l(3)02540, CG4195, lethal(3)73Ah, L(3)73Ah, I(3)73Ah" "IPR017907=Zinc finger, RING-type, conserved site, IPR018957=Zinc finger, C3HC4 RING-type, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG4195 16-Dec-15 2015_12 "ENSDARG00000052388(pcgf5b),ENSDARG00000071007(pcgf5a)" ENSXETG00000004916(rnf3) ENSMUSG00000033623(Pcgf3) ENSG00000185619(PCGF3) " embryonic stage -- adult stage , oogenesis stage && adult stage | female , larval stage && adult stage " " ovary

, fat body

" "lethal,recessive,wild-type,viable,visible" "adult abdomen,trichogen cell,mesothoracic tergum" DRSC11359 E -0.242281382 -0.67886684 -0.102363826 -1.684949359 -0.870630189 0.441301766 FBgn0261614 CG42703 http://flybase.net/reports/FBgn0261614.html protein_coding_gene IPR029375=Protein of unknown function DUF4558 CG42703 16-Dec-15 2015_12 FBgn0085358 Diedel3 Diedel 3 http://flybase.net/reports/FBgn0085358.html protein_coding_gene 0005615=extracellular space "CG14189, Diedel-3, CG34329" IPR025061=Protein of unknown function DUF4002 CG34329 16-Dec-15 2015_12 viable FBgn0267867 CR46155 http://flybase.net/reports/FBgn0267867.html pseudogene_attribute CR46155 16-Dec-15 2015_12 FBgn0265735 CR44542 http://flybase.net/reports/FBgn0265735.html non_protein_coding_gene "lincRNA.489, incRNA.489" CR44542 16-Dec-15 2015_12 FBgn0011902 tRNA:K5:29A transfer RNA:lys5:29A http://flybase.net/reports/FBgn0011902.html "FBgn0003793, FBgn0011901, FBgn0051899, FBgn0060177" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033443=AAA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K:TTT:AE002690, AE002690.trna3-LysTTT, tRNA:K5, tRNA:lys5:29A, CR31899, lys-tRNA-5, chr2L.trna11-LysTTT" CR31899 16-Dec-15 2015_12 FBgn0005545 l(3)72Dm lethal (3) 72Dm http://flybase.net/reports/FBgn0005545.html gene 16-Dec-15 2015_12 lethal FBgn0034740 nsr novel spermatogenesis regulator http://flybase.net/reports/FBgn0034740.html protein_coding_gene 0003723=RNA binding "0007288=sperm axoneme assembly, 0010608=posttranscriptional regulation of gene expression, 0007291=sperm individualization" 0016607=nuclear speck "cg3875, CG3875" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG3875 16-Dec-15 2015_12 WBGene00022101(Y69A2AR.32) "male sterile,recessive" "cystic bulge,investment cone,waste bag,individualization stage spermatid,spermatid axoneme" FBgn0039115 CG10214 http://flybase.net/reports/FBgn0039115.html protein_coding_gene "0008946=oligonucleotidase activity, 0000175=3'-5'-exoribonuclease activity, 0003676=nucleic acid binding" 0009267=cellular response to starvation "0005634=nucleus, 0005739=mitochondrion" "IPR012337=Ribonuclease H-like domain, IPR013520=Exonuclease, RNase T/DNA polymerase III" CG10214 16-Dec-15 2015_12 ENSDARG00000009806(smfn) YLR059C(REX2) WBGene00007429(C08B6.8) ENSXETG00000012648(REXO2) ENSMUSG00000032026(Rexo2) ENSG00000076043(REXO2) viable FBgn0040342 CG3706 http://flybase.net/reports/FBgn0040342.html "FBgn0015724, FBgn0029543" protein_coding_gene "EG:BAC7A4.20, ESTS:99F6T, EG:BACR7A4.20" CG3706 16-Dec-15 2015_12 WBGene00015469(C05D2.8) viable FBgn0060704 l(3)S071411b lethal (3) S071411b http://flybase.net/reports/FBgn0060704.html gene 0714/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0025491 l(3)82Db lethal (3) 82Db http://flybase.net/reports/FBgn0025491.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040496 CG17104 http://flybase.net/reports/FBgn0040496.html FBgn0032279 protein_coding_gene BEST:LD16579 CG17104 16-Dec-15 2015_12 FBgn0051294 CG31294 http://flybase.net/reports/FBgn0051294.html "FBgn0045186, FBgn0045287, FBgn0063719" protein_coding_gene "NEST:bs25d10, NEST:bs15e12, BcDNA:AT21457" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat" CG31294 16-Dec-15 2015_12 WBGene00016375(C33H5.8) FBgn0020781 smoq small monoene quantities http://flybase.net/reports/FBgn0020781.html gene 0042810=pheromone metabolic process 16-Dec-15 2015_12 FBgn0065928 l(2)SH0141 lethal (2) SH0141 http://flybase.net/reports/FBgn0065928.html gene l(2)SH2 0141 16-Dec-15 2015_12 "lethal,recessive" FBgn0263532 mir-4962 mir-4962 stem loop http://flybase.net/reports/FBgn0263532.html miRNA_gene "CR43517, dme-mir-4962" CR43517 16-Dec-15 2015_12 FBgn0002146 l(2)K508 lethal (2) K508 http://flybase.net/reports/FBgn0002146.html gene 16-Dec-15 2015_12 lethal FBgn0085655 CG41494 http://flybase.net/reports/FBgn0085655.html FBan0041494 protein_coding_gene 16-Dec-15 2015_12 FBgn0083942 CG34106 http://flybase.net/reports/FBgn0083942.html protein_coding_gene CG34106 16-Dec-15 2015_12 FBgn0037716 CG8273 http://flybase.net/reports/FBgn0037716.html protein_coding_gene "0003676=nucleic acid binding, 0003725=double-stranded RNA binding" cg8273 "IPR000467=G-patch domain, IPR014720=Double-stranded RNA-binding domain" CG8273 16-Dec-15 2015_12 WBGene00017025(D1037.1) viable FBgn0023075 l(1)19Cd lethal (1) 19Cd http://flybase.net/reports/FBgn0023075.html gene 800D9 16-Dec-15 2015_12 "lethal,recessive" FBgn0037180 CG14452 http://flybase.net/reports/FBgn0037180.html FBgn0062996 protein_coding_gene BcDNA:RE59202 CG14452 16-Dec-15 2015_12 FBgn0052127 tRNA:CR32127 transfer RNA:CR32127 http://flybase.net/reports/FBgn0052127.html FBgn0060165 tRNA_gene 0033404=UUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:L:CAA:AE002602, AE002602.trna19-LeuCAA, CR32127, chr3L.trna25-LeuCAA" CR32127 16-Dec-15 2015_12 FBgn0083940 RhoU RhoU http://flybase.net/reports/FBgn0083940.html "FBan0012102, FBgn0030179, FBgn0030180" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0007264=small GTPase mediated signal transduction 0005622=intracellular "CG12102, CG34104, CG12094" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type" CG34104 16-Dec-15 2015_12 viable DRSC25197 K -0.125687542 0.254871148 0.279029929 0.690131491 1.774257895 0.642517213 FBgn0062666 EP3135 EP3135 http://flybase.net/reports/FBgn0062666.html gene EP(3)3135 16-Dec-15 2015_12 FBgn0065040 6BP 6BP http://flybase.net/reports/FBgn0065040.html gene "D6BP, Drosophila INT6 binding protein" 16-Dec-15 2015_12 FBgn0040965 CR13130 http://flybase.net/reports/FBgn0040965.html non_protein_coding_gene CG13130 CR13130 16-Dec-15 2015_12 "long lived,lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" DRSC02226 IE -1.845302701 -5.401974178 0.298412135 -4.333488201 -1.420584717 -1.326632042 FBgn0062631 Mab3 Monoclonal antibody 3 http://flybase.net/reports/FBgn0062631.html gene 16-Dec-15 2015_12 FBgn0085553 CG41012 http://flybase.net/reports/FBgn0085553.html FBan0041012 protein_coding_gene 16-Dec-15 2015_12 FBgn0000367 cra crack http://flybase.net/reports/FBgn0000367.html gene 0008258=head involution 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive" embryonic head FBgn0082962 snoRNA:ë¬28S-3385a snoRNA:ë¬28S-3385a http://flybase.net/reports/FBgn0082962.html snoRNA_gene "psi28s-3385a, CR34608, Psi 28S-3385a" CR34608 16-Dec-15 2015_12 FBgn0001198 His2B Histone H2B http://flybase.net/reports/FBgn0001198.html FBgn0039974 protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome "histone H2B, H2[[B]], dH2b, histone H3, his, histone 2B, histone, Histone 2B, histone H2b, His2b, core histone, DmeH2b, Histone, Histone2B, HisC, H2B, H2b, histone h2b, dH2B" "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000558=Histone H2B" 16-Dec-15 2015_12 FBgn0263036 CG43331 http://flybase.net/reports/FBgn0263036.html "FBgn0037168, FBan0012377" protein_coding_gene CG12377 CG43331 16-Dec-15 2015_12 viable FBgn0266586 CR45111 http://flybase.net/reports/FBgn0266586.html non_protein_coding_gene CR45111 16-Dec-15 2015_12 FBgn0069177 mcl(2)Z3534 mcl(2)Z3534 http://flybase.net/reports/FBgn0069177.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0264894 CG44085 http://flybase.net/reports/FBgn0264894.html "FBgn0032497, FBgn0032498" protein_coding_gene "CG6108, CG6043" CG44085 16-Dec-15 2015_12 FBgn0261444 CG3638 http://flybase.net/reports/FBgn0261444.html "FBgn0026875, FBgn0070027" protein_coding_gene 0005254=chloride channel activity "0006909=phagocytosis, 0016319=mushroom body development, 0002121=inter-male aggressive behavior, 0006821=chloride transport" 0005886=plasma membrane "TTYH2, BG00376, EG:33C11.3, tweety-2" IPR006990=Tweety CG3638 16-Dec-15 2015_12 "ENSDARG00000010727(ttyh2l),ENSDARG00000016934(ttyh2),ENSDARG00000007678(zgc:123242),ENSDARG00000034473(LOC556314)" "ENSXETG00000021763(TTYH3),ENSXETG00000012828(Q6P1U2_XENTR),ENSXETG00000010394(),ENSXETG00000003389()" "ENSMUSG00000034714(Ttyh2),ENSMUSG00000036565(Ttyh3),ENSMUSG00000030428(Ttyh1)" "ENSG00000136295(TTYH3),ENSG00000141540(TTYH2),ENSG00000167614(TTYH1)" DRSC18533 E -0.01778315 0.995944868 1.882617982 0.230868316 -0.491594347 -0.127829802 FBgn0038099 CG7091 http://flybase.net/reports/FBgn0038099.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG7091 16-Dec-15 2015_12 "YOR378W(),YML116W(ATR1),YMR279C()" "viable,fertile" FBgn0032719 CG17321 http://flybase.net/reports/FBgn0032719.html protein_coding_gene CG17321 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263278 Fic Fic domain-containing protein http://flybase.net/reports/FBgn0263278.html "FBgn0021929, FBgn0031812" protein_coding_gene 0070733=protein adenylyltransferase activity "0051608=histamine transport, 0018117=protein adenylylation, 0050908=detection of light stimulus involved in visual perception, 0007632=visual behavior" 0005886=plasma membrane "l(2)k11101, lethal (2) k11101, CG9523" "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR003812=Fido domain" CG9523 16-Dec-15 2015_12 ENSDARG00000035595(ficd) WBGene00014004(fic-1) ENSXETG00000017652(FICD) ENSMUSG00000053334(Ficd) ENSG00000198855(FICD) FBgn0046700 Penelope\ORF1 ORF1 http://flybase.net/reports/FBgn0046700.html transposable_element_gene "IPR000305=GIY-YIG nuclease superfamily, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0031611 CG17840 http://flybase.net/reports/FBgn0031611.html protein_coding_gene 0042578=phosphoric ester hydrolase activity IPR002013=SAC domain CG17840 16-Dec-15 2015_12 YNL325C(FIG4) WBGene00007912(C34B7.2) ENSMUSG00000038417(Fig4) ENSG00000112367(FIG4) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039239 CG13641 http://flybase.net/reports/FBgn0039239.html protein_coding_gene CG13641 16-Dec-15 2015_12 viable FBgn0035719 tow target of wingless http://flybase.net/reports/FBgn0035719.html protein_coding_gene "0001736=establishment of planar polarity, 0035317=imaginal disc-derived wing hair organization, 0045879=negative regulation of smoothened signaling pathway" 0005634=nucleus "Tow, CG14821, Target of Wingless" IPR027967=Protein of unknown function DUF4612 CG14821 16-Dec-15 2015_12 "visible,viable,fertile" "wing vein L3,wing vein L4,1st posterior cell,wing,wing hair,supernumerary,microchaeta & adult thoraxap-md544,macrochaeta & adult thoraxap-md544,scutellum,wing blade,anterior wing margin,distal" DRSC23125 K -2.016290594 -0.300568405 FBgn0259316 EP-339 http://flybase.net/reports/FBgn0259316.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0031708 CG7382 http://flybase.net/reports/FBgn0031708.html protein_coding_gene 0030150=protein import into mitochondrial matrix 0005744=mitochondrial inner membrane presequence translocase complex IPR013261=Mitochondrial import inner membrane translocase subunit Tim21 CG7382 16-Dec-15 2015_12 ENSDARG00000071594(LOC560369) YGR033C(TIM21) WBGene00018934(F56B3.11) ENSXETG00000023559(TEgg075k22.1) ENSMUSG00000024645(1700034H14Rik) ENSG00000075336(C18orf55) FBgn0065309 l(2)SH1958 lethal (2) SH1958 http://flybase.net/reports/FBgn0065309.html gene l(2)SH2 1958 16-Dec-15 2015_12 "lethal,recessive" FBgn0020880 CG7179 http://flybase.net/reports/FBgn0020880.html protein_coding_gene 0008039=synaptic target recognition "anon-28Cg, CT22169, Opa, tld-like" "IPR021587=Transcription activator LAG-3, IPR000859=CUB domain" CG7179 16-Dec-15 2015_12 viable FBgn0260719 CR42546 http://flybase.net/reports/FBgn0260719.html pseudogene_attribute CR42546 16-Dec-15 2015_12 FBgn0003228 red red Malpighian tubules http://flybase.net/reports/FBgn0003228.html gene "bw-l, brown-like" 16-Dec-15 2015_12 "viable,recessive,eye color defective,visible" "pigment cell,Malpighian tubule,eye" FBgn0037352 CG14673 http://flybase.net/reports/FBgn0037352.html protein_coding_gene 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0053267 CG33267 http://flybase.net/reports/FBgn0053267.html protein_coding_gene CG33267 16-Dec-15 2015_12 FBgn0065583 l(2)SH0924 lethal (2) SH0924 http://flybase.net/reports/FBgn0065583.html gene l(2)SH2 0924 16-Dec-15 2015_12 "lethal,recessive" FBgn0027282 l(1)G0186 lethal (1) G0186 http://flybase.net/reports/FBgn0027282.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0020530 l(3)9C3 lethal (3) 9C3 http://flybase.net/reports/FBgn0020530.html gene 16-Dec-15 2015_12 FBgn0050424 CG30424 http://flybase.net/reports/FBgn0050424.html protein_coding_gene mdcds_18556 IPR024810=Mab-21 domain CG30424 16-Dec-15 2015_12 FBgn0003674 Tch Thin chaetae http://flybase.net/reports/FBgn0003674.html gene 16-Dec-15 2015_12 FBgn0015861 anon-21Aa anon-21Aa http://flybase.net/reports/FBgn0015861.html gene 16-Dec-15 2015_12 FBgn0051538 CG31538 http://flybase.net/reports/FBgn0051538.html "FBgn0045177, FBgn0045343, FBgn0045350, FBgn0045352, FBgn0045423, FBgn0045767, FBgn0045805, FBgn0045817, FBgn0045825, FBgn0064995" protein_coding_gene "BEST:GH27336, BcDNA:AT27831, BEST:GH11373, NEST:bs26g11, NEST:bs09e09, BEST:GH20014, NEST:bs02h07, NEST:bs09g01, NEST:bs10d08, BEST:LP11873" CG31538 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0011936 tRNA:N5:42Af transfer RNA:asn5:42Af http://flybase.net/reports/FBgn0011936.html "FBgn0003759, FBgn0053973, FBgn0060131" tRNA_gene "0033442=AAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna98-AsnGTT, Asn-tRNA-6, CR33973, tRNA:asn5:42Af, Asn6, AE002769.trna7-AsnGTT, tRNA:N:GTT:AE002769-c" CR33973 16-Dec-15 2015_12 FBgn0040271 Sulf1 Sulfated http://flybase.net/reports/FBgn0040271.html FBgn0038413 protein_coding_gene 0008449=N-acetylglucosamine-6-sulfatase activity "0030202=heparin metabolic process, 0045879=negative regulation of smoothened signaling pathway, 0008045=motor neuron axon guidance, 0045880=positive regulation of smoothened signaling pathway, 0007389=pattern specification process, 0030178=negative regulation of Wnt signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0016201=synaptic target inhibition" 0005615=extracellular space "DSulf, DSulf1, CG6725, Neu5, sulf1, Dsulf1, sulfated" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR000917=Sulfatase, IPR024609=Extracellular sulfatase, C-terminal, IPR024607=Sulfatase, conserved site" CG6725 16-Dec-15 2015_12 "ENSDARG00000038428(sulf1),ENSDARG00000013838(si:dkeyp-84g9.1),ENSDARG00000018423(sulf2)" WBGene00006308(sul-1) "ENSXETG00000003484(SULF2),ENSXETG00000015231(sulf1)" "ENSMUSG00000006800(Sulf2),ENSMUSG00000016918(Sulf1)" "ENSG00000196562(SULF2),ENSG00000137573(SULF1)" embryonic stage | stage 5 ventral neurogenic region | restricted

"visible,viable,fertile,somatic clone,lethal,partially lethal - majority die,some die during pupal stage" "anterior crossvein,wing,eye,wing margin,mechanosensory chaeta,supernumerary,taste bristle,1st posterior cell,somatic clone,anterior wing margin,wing margin bristle,external sensory organ precursor cell,wing blade,wing vein L2,imaginal tracheoblast,posterior crossvein,wing vein L4,wing vein L5,trichogen cell,mesothoracic tergum" FBgn0005274 l(3)SG94 lethal (3) SG94 http://flybase.net/reports/FBgn0005274.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0015468 l(2)44Fc lethal (2) 44Fc http://flybase.net/reports/FBgn0015468.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028614 l(2)W11 lethal (2) W11 http://flybase.net/reports/FBgn0028614.html gene l(2R)W11 16-Dec-15 2015_12 "lethal,recessive" FBgn0267027 CR45471 http://flybase.net/reports/FBgn0267027.html non_protein_coding_gene CR45471 16-Dec-15 2015_12 FBgn0036493 CG7255 http://flybase.net/reports/FBgn0036493.html "FBtr0075609, FBpp0075362, FBtr0075610, FBpp0075363, FBtr0075611, FBpp0075364, FBtr0075612, FBpp0075365, FBtr0075613, FBpp0075366" protein_coding_gene "0015171=amino acid transmembrane transporter activity, 0015174=basic amino acid transmembrane transporter activity" "0003333=amino acid transmembrane transport, 0000398=mRNA splicing, via spliceosome" "0016020=membrane, 0071011=precatalytic spliceosome" "IPR002293=Amino acid/polyamine transporter I, IPR029485=Cationic amino acid transporter, C-terminal" CG7255 16-Dec-15 2015_12 "YEL063C(CAN1),YFL055W(AGP3),YBR069C(TAT1),YNL270C(ALP1),YNL268W(LYP1),YDR508C(GNP1),YCL025C(AGP1),YDR046C(BAP3),YBR068C(BAP2),YKR039W(GAP1),YOL020W(TAT2),YGR191W(HIP1),YPL274W(SAM3),YPL265W(DIP5),YLL061W(MMP1),YOR348C(PUT4),YBR132C(AGP2),YDR160W(SSY1)" "viable,fertile" DRSC10790 K 0.89798475 0.95138133 0.454476163 0.181321083 -1.908011368 0.45009654 FBgn0038240 CG14851 http://flybase.net/reports/FBgn0038240.html protein_coding_gene CG14851 16-Dec-15 2015_12 viable FBgn0033271 CG8708 http://flybase.net/reports/FBgn0033271.html "FBgn0044522, FBgn0044769" protein_coding_gene "0016263=glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity, 0048531=beta-1,3-galactosyltransferase activity" "0006486=protein glycosylation, 0016266=O-glycan processing" "0005797=Golgi medial cisterna, 0016020=membrane" "anon-WO0140519.114, anon-WO0144478.10, dC1GalT2" "IPR026842=C1GALT1, IPR003378=Fringe-like" CG8708 16-Dec-15 2015_12 "ENSDARG00000055585(c1galt1a),ENSDARG00000055561(c1galt1b)" WBGene00008019(C38H2.2) "ENSXETG00000007295(C1GALT1),ENSXETG00000006215(),ENSXETG00000009666(),ENSXETG00000025171()" ENSMUSG00000042460(C1galt1) ENSG00000106392(C1GALT1) "viable,fertile" FBgn0086558 Ubi-p5E Ubiquitin-5E http://flybase.net/reports/FBgn0086558.html "FBgn0014439, FBgn0052744, FBgn0029855" protein_coding_gene 0031386=protein tag "0006511=ubiquitin-dependent protein catabolic process, 0006464=cellular protein modification process, 0016567=protein ubiquitination" "0005875=microtubule associated complex, 0005704=polytene chromosome band" "Ubiq, UB, CG18282, CG32744, CR32744, DmUbi-p5E, Ubi, ubiquitin, Ub, Ubiquitin" "IPR029071=Ubiquitin-related domain, IPR019954=Ubiquitin conserved site, IPR000626=Ubiquitin domain, IPR019956=Ubiquitin" CG32744 16-Dec-15 2015_12 ENSDARG00000001972(tpst2) YLL039C(UBI4) viable FBgn0013694 mt:tRNA:G mitochondrial glycine tRNA http://flybase.net/reports/FBgn0013694.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "CR34075, glycine tRNA, mtdbD00006301, tRNA-Gly, tRNA[Gly]" CR34075 16-Dec-15 2015_12 FBgn0038795 CG4335 http://flybase.net/reports/FBgn0038795.html protein_coding_gene "0008336=gamma-butyrobetaine dioxygenase activity, 0005506=iron ion binding, 0050353=trimethyllysine dioxygenase activity, 0031418=L-ascorbic acid binding" "0045329=carnitine biosynthetic process, 0055114=oxidation-reduction process" "IPR012776=Trimethyllysine dioxygenase, IPR003819=TauD/TfdA-like domain, IPR010376=Domain of unknown function DUF971" CG4335 16-Dec-15 2015_12 YHL021C(AIM17) WBGene00001523(gbh-2) ENSXETG00000018382(TMLHE) ENSMUSG00000079834 ENSG00000185973(TMLHE) viable FBgn0004594 Eig71Eg Ecdysone-induced gene 71Eg http://flybase.net/reports/FBgn0004594.html protein_coding_gene 0042742=defense response to bacterium 0005576=extracellular region "gene VI, L71-6, gene-VI, L71, CG7336, 71E-Gene-VI, VI, Gene VI, eig71Eg" IPR003475=Insect protein of unknown function CG7336 16-Dec-15 2015_12 viable FBgn0086294 GS14505 http://flybase.net/reports/FBgn0086294.html gene 14505 16-Dec-15 2015_12 FBgn0002758 mit(1)8 mitotic 8 http://flybase.net/reports/FBgn0002758.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0035861 CG7213 http://flybase.net/reports/FBgn0035861.html protein_coding_gene CG7213 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0037359 MED27 Mediator complex subunit 27 http://flybase.net/reports/FBgn0037359.html protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0003712=transcription cofactor activity" "0007406=negative regulation of neuroblast proliferation, 0071390=cellular response to ecdysone, 0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0043457=regulation of cellular respiration, 0046425=regulation of JAK-STAT cascade" "0016592=mediator complex, 0005634=nucleus" "med27, CRSP34, dCrsp34, dTRAP37, dCRSP34, Med27, CG1245, Trap37" "IPR021627=Mediator complex, subunit Med27" CG1245 16-Dec-15 2015_12 ENSDARG00000009681(crsp8) ENSXETG00000001486(crsp8) ENSMUSG00000026799(Med27) ENSG00000160563(MED27) viable DRSC12205 K -1.258498246 0.255669867 -1.286068482 -0.58532536 1.624719547 0.663344617 FBgn0259977 Tdc1 Tyrosine decarboxylase 1 http://flybase.net/reports/FBgn0259977.html "FBgn0050445, FBgn0033091, FBgn0061477" protein_coding_gene "0030170=pyridoxal phosphate binding, 0004837=tyrosine decarboxylase activity, 0004058=aromatic-L-amino-acid decarboxylase activity" "0006520=cellular amino acid metabolic process, 0048149=behavioral response to ethanol" "CG3686, tyrosine decarboxylase, tdc, dTdc1, Tyramine decarboxylase 1, CG30445, tdc1" "IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR010977=Aromatic-L-amino-acid decarboxylase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR021115=Pyridoxal-phosphate binding site, IPR015424=Pyridoxal phosphate-dependent transferase" CG30445 16-Dec-15 2015_12 FBgn0082362 HM12 HM12 http://flybase.net/reports/FBgn0082362.html gene 16-Dec-15 2015_12 FBgn0259843 Su(Ste):CR42412 Su(Ste):CR42412 http://flybase.net/reports/FBgn0259843.html non_protein_coding_gene CR42412 CR42412 16-Dec-15 2015_12 FBgn0014293 l(3)64Bd lethal (3) 64Bd http://flybase.net/reports/FBgn0014293.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261015 Pif1A PFTAIRE-interacting factor 1A http://flybase.net/reports/FBgn0261015.html "FBgn0037628, FBgn0037629, FBgn0052940, FBgn0053719, FBtr0081936, FBpp0081418, FBtr0081937, FBpp0081419, FBtr0081938, FBpp0081420, FBtr0081939, FBpp0081421, FBgn0260443, FBgn0027540, FBgn0037631" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" "CG11773, CG11774, CG33719, PIF-1A, BcDNA:GH12504, CG42599, Pif1, CG33719/CG33720, CG11776, DM22, CG32940, CG9808" IPR004827=Basic-leucine zipper domain CG42599 16-Dec-15 2015_12 DRSC14142 I -1.639487553 0.29632076 -0.175923619 -0.760434039 0.773471813 -0.742831016 FBgn0031031 CG14218 http://flybase.net/reports/FBgn0031031.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH211 CG14218 16-Dec-15 2015_12 viable DRSC19575 K -0.939859044 0.191055312 0.430723485 0.000445834 -0.104857886 1.654702547 FBgn0259940 ttd3 TRPL translocation defect 3 http://flybase.net/reports/FBgn0259940.html protein_coding_gene TRPL translocation defect 3 16-Dec-15 2015_12 FBgn0030960 Atg101 Autophagy-related 101 http://flybase.net/reports/FBgn0030960.html protein_coding_gene "0046983=protein dimerization activity, 0019901=protein kinase binding, 0019904=protein domain specific binding" "0016239=positive regulation of macroautophagy, 0006914=autophagy" 0034273=ATG1/UKL1 signaling complex "CG7053, Autophagy-specific gene 101, Atg101" IPR012445=Autophagy-related protein 1010 CG7053 16-Dec-15 2015_12 ENSDARG00000043287(zgc:123177) WBGene00022078(Y69A2AR.7) ENSMUSG00000037204(9430023L20Rik) ENSG00000123395(C12orf44) viable FBgn0026207 mbo members only http://flybase.net/reports/FBgn0026207.html "FBgn0010853, FBgn0023005, FBgn0038075, FBgn0062136" protein_coding_gene 0005515=protein binding "0019730=antimicrobial humoral response, 0006606=protein import into nucleus, 0035147=branch fusion, open tracheal system, 0006955=immune response, 0022008=neurogenesis, 0007424=open tracheal system development, 0046826=negative regulation of protein export from nucleus" "0005635=nuclear envelope, 0005643=nuclear pore" "Dnup 88, 1465/7, 1465/07, DNup88, Mbo, anon-WO0118547.263, unnamed, l(3)05043, Dnup88, nup88, l(3)S146507, Nup88, CG6819, dNup88" IPR019321=Nucleoporin Nup88 CG6819 16-Dec-15 2015_12 ENSDARG00000003235(nup88) ENSXETG00000021359(NUP88) ENSMUSG00000040667(Nup88) ENSG00000108559(NUP88) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,wild-type,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible" "embryonic/larval dorsal branch,embryonic/larval dorsal anastomosis,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0265142 Ir56e Ionotropic receptor 56e http://flybase.net/reports/FBgn0265142.html pseudogene_attribute "DmelIR56e, CR44211" CR44211 16-Dec-15 2015_12 FBgn0263893 l(3)H67 http://flybase.net/reports/FBgn0263893.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0051600 CG31600 http://flybase.net/reports/FBgn0051600.html protein_coding_gene 0016021=integral component of membrane "IPR008952=Tetraspanin, EC2 domain" CG31600 16-Dec-15 2015_12 "viable,fertile" FBgn0028415 Met75Cb Met75Cb http://flybase.net/reports/FBgn0028415.html FBgn0036788 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "bs14h01.y1, CG18064" CG18064 16-Dec-15 2015_12 FBgn0002291 l(3)80Fb lethal (3) 80Fb http://flybase.net/reports/FBgn0002291.html gene "l7, l(3)Lh7, 80Fb, lethal 7" 16-Dec-15 2015_12 lethal FBgn0030645 CG6308 http://flybase.net/reports/FBgn0030645.html protein_coding_gene 0046331=lateral inhibition "Alg14, dAlg14" IPR013969=Oligosaccharide biosynthesis protein Alg14-like CG6308 16-Dec-15 2015_12 ENSDARG00000039671(alg14) YBR070C(ALG14) WBGene00019725(M02B7.4) ENSMUSG00000039887(Alg14) ENSG00000172339(ALG14) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0034383 CG17821 http://flybase.net/reports/FBgn0034383.html protein_coding_gene 0009922=fatty acid elongase activity 0030497=fatty acid elongation 0016021=integral component of membrane IPR002076=ELO family CG17821 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" viable FBgn0259290 C386 http://flybase.net/reports/FBgn0259290.html gene 16-Dec-15 2015_12 visible wing hair FBgn0061505 l(2)24Ae lethal (2) 24Ae http://flybase.net/reports/FBgn0061505.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001652 l(1)ds4 lethal (1) discs small 4 http://flybase.net/reports/FBgn0001652.html gene l(1)d.sml.-4 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264550 CR43929 http://flybase.net/reports/FBgn0264550.html non_protein_coding_gene CR43929 16-Dec-15 2015_12 FBgn0260802 EP2-760 http://flybase.net/reports/FBgn0260802.html gene 16-Dec-15 2015_12 FBgn0036824 CG3902 http://flybase.net/reports/FBgn0036824.html FBgn0036823 protein_coding_gene "0016937=short-branched-chain-acyl-CoA dehydrogenase activity, 0050660=flavin adenine dinucleotide binding" 0055114=oxidation-reduction process "0005739=mitochondrion, 0005829=cytosol" "Acyl-coenzyme A dehydrogenase homolog, GH07925p, CG18168, CT12987, CG 3902" "IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006089=Acyl-CoA dehydrogenase, conserved site, IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal" CG3902 16-Dec-15 2015_12 "WBGene00016943(acdh-1),WBGene00019433(acdh-3)" ENSXETG00000009561(acadsb) ENSMUSG00000030861(Acadsb) ENSG00000196177(ACADSB) FBgn0028586 l(?)H81 lethal (?) H81 http://flybase.net/reports/FBgn0028586.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0032770 CG13086 http://flybase.net/reports/FBgn0032770.html protein_coding_gene 0030246=carbohydrate binding "IPR016187=C-type lectin fold, IPR001304=C-type lectin, IPR016186=C-type lectin-like" CG13086 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0050101 CG30101 http://flybase.net/reports/FBgn0050101.html "FBgn0034211, FBgn0034212" protein_coding_gene "CG15901, CG6564, FBgn0050101, vajk-4" CG30101 16-Dec-15 2015_12 ENSXETG00000000145() "viable,fertile" FBgn0010650 l(2)08685 lethal (2) 08685 http://flybase.net/reports/FBgn0010650.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262987 CG43295 http://flybase.net/reports/FBgn0262987.html protein_coding_gene CG43295 16-Dec-15 2015_12 FBgn0013740 wako walkabout http://flybase.net/reports/FBgn0013740.html gene 16-Dec-15 2015_12 "lethal,recessive,neuroanatomy defective" FBgn0029594 CG14806 http://flybase.net/reports/FBgn0029594.html protein_coding_gene Apop1 IPR018796=Uncharacterised protein family UPF0671 CG14806 16-Dec-15 2015_12 WBGene00012693(Y39B6A.34) ENSMUSG00000037787(2810002N01Rik) ENSG00000127150 "immune response defective,viable" FBgn0264943 CR44112 http://flybase.net/reports/FBgn0264943.html non_protein_coding_gene CR44112 16-Dec-15 2015_12 FBgn0022193 l(2)k05103 lethal (2) k05103 http://flybase.net/reports/FBgn0022193.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014295 l(3)64Bf lethal (3) 64Bf http://flybase.net/reports/FBgn0014295.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000355 Cp15 Chorion protein 15 http://flybase.net/reports/FBgn0000355.html protein_coding_gene 0005213=structural constituent of chorion "0007306=eggshell chorion assembly, 0007275=multicellular organismal development" 0042600=chorion "S15, Dms15, s-15, CG6519, unnamed, Cs15, s15, melcp15, E6, Chorion Protein 15, s15-1, Shell-15, Chorion prot 15, s15 chorion gene, cp15, C.s15" IPR005649=Chorion 2 CG6519 16-Dec-15 2015_12 " oogenesis stage | stage S8-10 , adult stage | female , oogenesis stage | stage S13-14 " adult stage | female " ovary

{ v mus101K451 } , ovary

, ovary

{ 0 swa6 } , ovary

{ v fs(1)A1059K1 } " viable FBgn0033919 CG8547 http://flybase.net/reports/FBgn0033919.html protein_coding_gene CG8547 16-Dec-15 2015_12 partially lethal - majority die FBgn0033521 CG12896 http://flybase.net/reports/FBgn0033521.html FBgn0040497 protein_coding_gene 0051920=peroxiredoxin activity "0055114=oxidation-reduction process, 0007498=mesoderm development, 0006979=response to oxidative stress" "0005737=cytoplasm, 0070062=extracellular exosome" "RH54193, BEST:LD11278, RE05501p, AOP2-related, DPx-2540-1 variant" "IPR012336=Thioredoxin-like fold, IPR024706=Peroxiredoxin, AhpC-type, IPR019479=Peroxiredoxin, C-terminal, IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant" CG12896 16-Dec-15 2015_12 YBL064C(PRX1) WBGene00021401(prdx-6) FBgn0036331 CG14117 http://flybase.net/reports/FBgn0036331.html FBgn0063014 protein_coding_gene BcDNA:RE44251 CG14117 16-Dec-15 2015_12 "viable,fertile" FBgn0260275 GSd499 http://flybase.net/reports/FBgn0260275.html gene 16-Dec-15 2015_12 lethal FBgn0013592 l(3)A164.1M3 lethal (3) A164.1M3 http://flybase.net/reports/FBgn0013592.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0039205 CG13623 http://flybase.net/reports/FBgn0039205.html FBgn0063218 protein_coding_gene "0005198=structural molecule activity, 0051536=iron-sulfur cluster binding" "0016226=iron-sulfur cluster assembly, 0046331=lateral inhibition" "IscA2 homologue, BcDNA:GH27470" "IPR016092=FeS cluster insertion protein, IPR000361=FeS cluster biogenesis" CG13623 16-Dec-15 2015_12 ENSDARG00000038154(LOC100150438) YPR067W(ISA2) WBGene00013218(Y54G11A.9) ENSMUSG00000021241(Isca2) ENSG00000165898(ISCA2) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,trichogen cell" FBgn0266573 tRNA:CR45106 transfer RNA:CR45106 http://flybase.net/reports/FBgn0266573.html "FBgn0050260, FBgn0011988, FBgn0060033" tRNA_gene 0033439=ACA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:CR30260, tRNA:T:TGT:AE002787-d, AE002787.trna33-ThrTGT, tRNA:T3:47F, tRNA[[Thr]], tRNA:thr3:47F, CR45106, tRNA[Thr][[3]], transfer RNA:CR30260, transfer RNA:thr3:47F, CR30260, chr2R.trna15-ThrTGT" CR45106 16-Dec-15 2015_12 FBgn0044011 Spn43Ad Serpin 43Ad http://flybase.net/reports/FBgn0044011.html FBgn0033147 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005615=extracellular space "CG1859, Spn43Ad" "IPR000215=Serpin family, IPR023795=Serpin, conserved site, IPR023796=Serpin domain" CG1859 16-Dec-15 2015_12 viable FBgn0058108 CG40108 http://flybase.net/reports/FBgn0058108.html FBan0040108 protein_coding_gene 16-Dec-15 2015_12 FBgn0028075 l(3)S088205 lethal (3) S088205 http://flybase.net/reports/FBgn0028075.html gene 0882/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0033706 Vha36-2 Vacuolar H+ ATPase 36kD subunit 2 http://flybase.net/reports/FBgn0033706.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0046961=proton-transporting ATPase activity, rotational mechanism" "0015992=proton transport, 0015991=ATP hydrolysis coupled proton transport" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0033176=proton-transporting V-type ATPase complex" "Vacuolar H[+] ATPase subunit 36-2, vha36-2, CG13167" "IPR002699=ATPase, V1 complex, subunit D" CG13167 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum DRSC06294 K 0.107204398 -0.031677463 -0.004433578 0.707520991 -1.642916985 -0.393137924 FBgn0260463 Unc-115b http://flybase.net/reports/FBgn0260463.html "FBgn0037733, FBgn0044536" protein_coding_gene "0008270=zinc ion binding, 0003779=actin binding" 0007010=cytoskeleton organization 0005654=nucleoplasm "unc-115, CG31332, CG9489, anon-WO0140519.9" "IPR003128=Villin headpiece, IPR001781=Zinc finger, LIM-type" CG31332 16-Dec-15 2015_12 FBgn0023094 cyc cycle http://flybase.net/reports/FBgn0023094.html "FBgn0024953, FBgn0025108" protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007622=rhythmic behavior, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0032922=circadian regulation of gene expression, 0045187=regulation of circadian sleep/wake cycle, sleep, 0045475=locomotor rhythm, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0003053=circadian regulation of heart rate, 0045893=positive regulation of transcription, DNA-templated, 0007623=circadian rhythm, 0048148=behavioral response to cocaine, 0042594=response to starvation, 0008062=eclosion rhythm" "0005667=transcription factor complex, 0005737=cytoplasm, 0005634=nucleus" "dBma1, CG8727, Mop3, Cycle, CYCLE, dCYC, BMAL1, bmal1, dBmal, dbmal1, dbmal, MOP3, CYC, Bmal1, dBMAL, Cyc, bMAL1, brain and muscle ARNT-like 1, dBMAL1, bHLHe7" "IPR001067=Nuclear translocator, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR000014=PAS domain, IPR013767=PAS fold, IPR001610=PAC motif" CG8727 16-Dec-15 2015_12 "ENSDARG00000006791(arntl1a),ENSDARG00000035732(arntl1b),ENSDARG00000041381(arntl2)" "ENSMUSG00000055116(Arntl),ENSMUSG00000040187(Arntl2)" "ENSG00000133794(ARNTL),ENSG00000029153(ARNTL2)" adult stage head

"locomotor rhythm defective,recessive,circadian rhythm defective,sleep defective,behavior defective,visual behavior defective,mating rhythm defective,male limited,eclosion rhythm defective,male,viable" LN period neuron FBgn0017567 ND-23 NADH dehydrogenase (ubiquinone) 23 kDa subunit http://flybase.net/reports/FBgn0017567.html FBgn0038370 protein_coding_gene "0051539=4 iron, 4 sulfur cluster binding, 0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "ND 23, NADH:ubiquinone reductase 23kD subunit precursor, NADH:ubiquinone oxidoreductase 23 kDa subunit, CG3944, NADH: UBIQUINONE REDUCTASE 23 KD SUBUNIT PRECURSOR, NADH-UBIQUINONE OXIDOREDUCTASE 23 KDA SUBUNIT, ND23, NADH ubiquinone oxidoreductase 23 kDa, COMPLEX I: 23 kDa subunit, NUIM" "IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR010226=NADH-quinone oxidoreductase, chain I, IPR017900=4Fe-4S ferredoxin, iron-sulphur binding, conserved site" CG3944 16-Dec-15 2015_12 "ENSDARG00000051986(ndufs8),ENSDARG00000057055" WBGene00020636(T20H4.5) ENSXETG00000020882(ndufs8) ENSMUSG00000059734(Ndufs8) ENSG00000110717(NDUFS8) "viable,visible" trichogen cell FBgn0031734 CG11147 http://flybase.net/reports/FBgn0031734.html protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" "0006810=transport, 0022008=neurogenesis" 0043190=ATP-binding cassette (ABC) transporter complex "IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR000412=ABC-2 transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site" CG11147 16-Dec-15 2015_12 ENSDARG00000071341 "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" ganglion mother cell FBgn0267878 CR46166 http://flybase.net/reports/FBgn0267878.html pseudogene_attribute Mst35Ba-related CR46166 16-Dec-15 2015_12 FBgn0022001 l(2)k09318 lethal (2) k09318 http://flybase.net/reports/FBgn0022001.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013228 E(var)130 E(var)130 http://flybase.net/reports/FBgn0013228.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0015435 l(1)5ACa lethal (1) 5ACa http://flybase.net/reports/FBgn0015435.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001815 l(1)ne nonevaginated http://flybase.net/reports/FBgn0001815.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "dorsal thoracic disc,ventral thoracic disc,genital disc,testis,pupal cuticle,imaginal disc" FBgn0024575 l(3)rK315 lethal (3) rK315 http://flybase.net/reports/FBgn0024575.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058455 2SrRNA:CR40455 2SrRNA:CR40455 http://flybase.net/reports/FBgn0058455.html rRNA_gene CR40455 16-Dec-15 2015_12 FBgn0086698 frtz fritz http://flybase.net/reports/FBgn0086698.html "FBgn0031358, FBgn0020302, FBgn0062241" protein_coding_gene "0001736=establishment of planar polarity, 0035320=imaginal disc-derived wing hair site selection" "anon-WO0118547.105, CG17657, fritz" "IPR024511=WD repeat-containing and planar cell polarity effector protein Fritz, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG17657 16-Dec-15 2015_12 ENSXETG00000013020(C2orf86) ENSMUSG00000020319(AV249152) ENSG00000143951(WDPCP) FBgn0069250 attP:Dps1 pseudo attP recognition site Dps1 http://flybase.net/reports/FBgn0069250.html region 16-Dec-15 2015_12 FBgn0010699 l(2)s4830 lethal (2) s4830 http://flybase.net/reports/FBgn0010699.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" "crystal cell,mitotic cell cycle" FBgn0266074 CR44827 http://flybase.net/reports/FBgn0266074.html non_protein_coding_gene CR44827 16-Dec-15 2015_12 FBgn0267228 CR45668 http://flybase.net/reports/FBgn0267228.html non_protein_coding_gene lincRNA.953 CR45668 16-Dec-15 2015_12 FBgn0037422 Osi13 Osiris 13 http://flybase.net/reports/FBgn0037422.html protein_coding_gene 0005887=integral component of plasma membrane "CG15595, Osiris" IPR012464=Protein of unknown function DUF1676 CG15595 16-Dec-15 2015_12 viable FBgn0034704 CG6758 http://flybase.net/reports/FBgn0034704.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO6 "IPR015915=Kelch-type beta propeller, IPR001810=F-box domain" CG6758 16-Dec-15 2015_12 ENSXETG00000023248(FBXO42) ENSMUSG00000028920(Fbxo42) ENSG00000037637(FBXO42) viable FBgn0265806 CR44595 http://flybase.net/reports/FBgn0265806.html non_protein_coding_gene lincRNA.122 CR44595 16-Dec-15 2015_12 FBgn0001056 Fs(3)Kel Female sterile (3) Keled http://flybase.net/reports/FBgn0001056.html gene "Fs(3)Keled, Fs(3)Sz15" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0033648 Ir48b Ionotropic receptor 48b http://flybase.net/reports/FBgn0033648.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG13195, ionotropic receptor 48b, IR48b, DmelIR48b" CG13195 16-Dec-15 2015_12 viable FBgn0266960 CR45411 http://flybase.net/reports/FBgn0266960.html non_protein_coding_gene CR45411 16-Dec-15 2015_12 FBgn0021754 2R-L 2R-L http://flybase.net/reports/FBgn0021754.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0002407 l(3)99Dh lethal (3) 99Dh http://flybase.net/reports/FBgn0002407.html gene 16-Dec-15 2015_12 lethal FBgn0085075 l(3)S024329 l(3)S024329 http://flybase.net/reports/FBgn0085075.html gene 16-Dec-15 2015_12 FBgn0005102 Gt-2 Giant on 2 http://flybase.net/reports/FBgn0005102.html gene "Giant in chromosome 2, Gt2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0260373 GSd480 http://flybase.net/reports/FBgn0260373.html gene 16-Dec-15 2015_12 lethal FBgn0002372 l(3)92Aa lethal (3) 92Aa http://flybase.net/reports/FBgn0002372.html FBgn0002378 gene "l(3)C4-1, l(3)BE70, Complementation group 4, l(3)C4-20, l(3)92Ad, l(3)91Fd, l(3)C4-6, l(3)C4-2, C4, l(3)BE72, l(3)BE71, l(3)C4-21" 16-Dec-15 2015_12 "lethal,recessive" FBgn0083304 E(smoDN)1575 Enhancer of smoDN 1575 http://flybase.net/reports/FBgn0083304.html gene 16-Dec-15 2015_12 FBgn0032789 CG13083 http://flybase.net/reports/FBgn0032789.html protein_coding_gene 0042600=chorion CG13083 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC28424 K 0.320902357 -0.151721468 -0.480618177 -0.310939835 1.604997907 4.361442544 FBgn0025348 anon-11a anon-11a http://flybase.net/reports/FBgn0025348.html gene 16-Dec-15 2015_12 FBgn0010320 Cdi12 Cyclin-dependent kinase interactor 12 http://flybase.net/reports/FBgn0010320.html gene "cdi12, CDI12" 16-Dec-15 2015_12 FBgn0065220 l(2)SH2232 lethal (2) SH2232 http://flybase.net/reports/FBgn0065220.html gene l(2)SH2 2232 16-Dec-15 2015_12 "lethal,recessive" FBgn0261703 gce germ cell-expressed bHLH-PAS http://flybase.net/reports/FBgn0261703.html "FBgn0030627, FBgn0030626" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity, 0008134=transcription factor binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0043069=negative regulation of programmed cell death, 0006355=regulation of transcription, DNA-templated" "0005737=cytoplasm, 0005634=nucleus, 0005667=transcription factor complex" "Gce/Met2, germ cell-expressed, Germ cell-expressed, germ cell expressed, Dmgce, germ-cell expressed, CG42739, CG6211, CG15032, GCE, Germ-cell expressed bHLH-PAS" "IPR001610=PAC motif, IPR001067=Nuclear translocator, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR000014=PAS domain" CG42739 16-Dec-15 2015_12 FBgn0029042 l(2)E22 lethal (2) E22 http://flybase.net/reports/FBgn0029042.html gene E22 16-Dec-15 2015_12 "lethal,recessive,phototaxis defective" FBgn0263901 l(3)CMV45 http://flybase.net/reports/FBgn0263901.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0051825 CG31825 http://flybase.net/reports/FBgn0051825.html protein_coding_gene 16-Dec-15 2015_12 FBgn0013334 Sap47 Synapse-associated protein 47kD http://flybase.net/reports/FBgn0013334.html protein_coding_gene "0007268=synaptic transmission, 0008306=associative learning, 0048172=regulation of short-term neuronal synaptic plasticity" 0045202=synapse "SAP47, CG8884, sap47, SAP 47, dsap-47, SAP-47" IPR005607=BSD domain CG8884 16-Dec-15 2015_12 ENSDARG00000012946(syap1) WBGene00007621(C16C2.4) ENSMUSG00000031357(Syap1) ENSG00000169895(SYAP1) "viable,fertile,learning defective" FBgn0262424 mir-10 mir-10 stem loop http://flybase.net/reports/FBgn0262424.html "FBgn0046833, FBgn0082182, FBgn0262270" miRNA_gene "miR-10*, mir-10S, CR32942, mir-10, dme-miR-10, miR-10, mir-10*, miR-10a, CR42977, dme-mir-10, dme-miR-10-5p, CR33565, pri-mir-10, MIR-10" CR42977 16-Dec-15 2015_12 "viable,visible,lethal" "wing,wing vein L3,wing vein L5,wing vein,ectopic,embryonic/larval cuticle" FBgn0001010 fs(3)A1 female sterile (3) A1 http://flybase.net/reports/FBgn0001010.html gene 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oocyte" FBgn0028481 CG4341 http://flybase.net/reports/FBgn0028481.html protein_coding_gene BcDNA:GH12144 "IPR013618=Domain of unknown function DUF1736, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG4341 16-Dec-15 2015_12 "ENSDARG00000045753(tmtc2),ENSDARG00000068527,ENSDARG00000035273(LOC555381)" WBGene00017983(F32D1.3) ENSMUSG00000036019(Tmtc2) ENSG00000179104(TMTC2) "viable,fertile" FBgn0037171 CG14459 http://flybase.net/reports/FBgn0037171.html protein_coding_gene CG14459 16-Dec-15 2015_12 lethal DRSC23039 K -0.422110396 -2.023866895 FBgn0263929 jvl javelin-like http://flybase.net/reports/FBgn0263929.html "FBgn0001293, FBgn0262718, FBgn0045903, FBgn0045914, FBgn0260465, FBgn0038259, FBgn0053330" protein_coding_gene "0006403=RNA localization, 0016325=oocyte microtubule cytoskeleton organization, 0030715=oocyte growth in germarium-derived egg chamber, 0046843=dorsal appendage formation, 0008407=chaeta morphogenesis, 0051663=oocyte nucleus localization involved in oocyte dorsal/ventral axis specification, 0051017=actin filament bundle assembly, 0030720=oocyte localization involved in germarium-derived egg chamber formation" 0015630=microtubule cytoskeleton "javelinlike, CG33330, CG3563, CG43162, anon-WO0153538.5, Javelin-Like, anon-WO0153538.4" CG43162 16-Dec-15 2015_12 FBgn0262409 mir-304 mir-304 stem loop http://flybase.net/reports/FBgn0262409.html "FBgn0067701, FBgn0262246" miRNA_gene 0045880=positive regulation of smoothened signaling pathway "CR33607, miR-304, CR42953, MiR-304, dme-mir-304, mir-304, 304, miR304" CR42953 16-Dec-15 2015_12 viable FBgn0037428 Osi18 Osiris 18 http://flybase.net/reports/FBgn0037428.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG1169" IPR012464=Protein of unknown function DUF1676 CG1169 16-Dec-15 2015_12 viable FBgn0065295 l(2)SH2001 lethal (2) SH2001 http://flybase.net/reports/FBgn0065295.html gene l(2)SH2 2001 16-Dec-15 2015_12 "lethal,recessive" FBgn0032304 CG17134 http://flybase.net/reports/FBgn0032304.html protein_coding_gene 0004190=aspartic-type endopeptidase activity 0006508=proteolysis "IPR001461=Aspartic peptidase, IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain" CG17134 16-Dec-15 2015_12 YPL154C(PEP4) "ENSMUSG00000023987(Pgc),ENSMUSG00000004552(Ctse)" "ENSG00000204973,ENSG00000172647,ENSG00000180860,ENSG00000196188(CTSE),ENSG00000096088(PGC)" viable FBgn0027981 l(3)S135710 lethal (3) S135710 http://flybase.net/reports/FBgn0027981.html gene 1357/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0033183 CG1620 http://flybase.net/reports/FBgn0033183.html protein_coding_gene 0003677=DNA binding 0005634=nucleus 146745_at "IPR017884=SANT domain, IPR001005=SANT/Myb domain, IPR000949=ELM2 domain, IPR009057=Homeodomain-like" CG1620 16-Dec-15 2015_12 "ENSDARG00000041072(mier1a),ENSDARG00000001447(LOC566167),ENSDARG00000006253(zgc:114199)" "WBGene00020320(T07F8.4),WBGene00017352(F10E7.11)" "ENSXETG00000012401(MIER1),ENSXETG00000015520(BC080986.1)" "ENSMUSG00000028522(Mier1),ENSMUSG00000032727(Mier3),ENSMUSG00000042570(Mier2)" "ENSG00000198160(MIER1),ENSG00000155545(MIER3),ENSG00000105556(MIER2)" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005730 l(1)TK206 lethal (1) TK206 http://flybase.net/reports/FBgn0005730.html gene l206 16-Dec-15 2015_12 lethal FBgn0002671 mat(2)ea-H maternal effect early arrest H http://flybase.net/reports/FBgn0002671.html gene "mat(2)earlyRU28, RU28" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0260626 d00992 http://flybase.net/reports/FBgn0260626.html gene 16-Dec-15 2015_12 visible wing FBgn0038494 beat-IIb beat-IIb http://flybase.net/reports/FBgn0038494.html FBgn0038493 protein_coding_gene 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "CT13620, Beat-IIb, beat IIb, CG14337, CG4135" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR007110=Immunoglobulin-like domain" CG4135 16-Dec-15 2015_12 viable DRSC13219 I -1.753198168 0.211633154 -0.238612904 -0.111140162 0.612141904 0.513563986 FBgn0083066 quil quilapan http://flybase.net/reports/FBgn0083066.html gene 16-Dec-15 2015_12 FBgn0052822 CG32822 http://flybase.net/reports/FBgn0052822.html protein_coding_gene 16-Dec-15 2015_12 "viable,fertile" FBgn0035036 CG4707 http://flybase.net/reports/FBgn0035036.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus Cg4707 "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4707 16-Dec-15 2015_12 viable FBgn0038718 CG17752 http://flybase.net/reports/FBgn0038718.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG17752 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0067646 sdv sedov http://flybase.net/reports/FBgn0067646.html gene 0045451=pole plasm oskar mRNA localization 16-Dec-15 2015_12 lethal "nurse cell,germline clone,follicle cell,supernumerary" FBgn0058182 CR40182 http://flybase.net/reports/FBgn0058182.html FBan0040182 pseudogene_attribute CG40182 CR40182 16-Dec-15 2015_12 FBgn0069448 E(br)24 E(br)24 http://flybase.net/reports/FBgn0069448.html gene "0008258=head involution, 0007391=dorsal closure" 16-Dec-15 2015_12 "lethal,recessive,visible,semidominant" "embryonic/first instar larval cuticle,anterior,leg" FBgn0034558 Cib2 CIB2 ortholog http://flybase.net/reports/FBgn0034558.html protein_coding_gene "0005509=calcium ion binding, 0004723=calcium-dependent protein serine/threonine phosphatase activity, 0008597=calcium-dependent protein serine/threonine phosphatase regulator activity" "0007602=phototransduction, 0055074=calcium ion homeostasis" 0005955=calcineurin complex "CG9236, cib2" "IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG9236 16-Dec-15 2015_12 "ENSDARG00000067919,ENSDARG00000032626(cib2)" WBGene00009260(F30A10.1) ENSXETG00000008733(cib3) ENSMUSG00000037493(Cib2) "ENSG00000136425(CIB2),ENSG00000141977(CIB3)" "visible,partially lethal - majority die,some die during pupal stage,neuroanatomy defective,conditional,neurophysiology defective" "trichogen cell,eye photoreceptor cell,conditional" FBgn0003480 spn-B spindle B http://flybase.net/reports/FBgn0003480.html protein_coding_gene "0005524=ATP binding, 0003677=DNA binding, 0008094=DNA-dependent ATPase activity, 0000150=recombinase activity" "0009951=polarity specification of dorsal/ventral axis, 0008298=intracellular mRNA localization, 0009994=oocyte differentiation, 0006302=double-strand break repair, 0007294=germarium-derived oocyte fate determination, 0006417=regulation of translation, 0030717=karyosome formation, 0007126=meiotic nuclear division, 0006281=DNA repair, 0006310=DNA recombination, 0007131=reciprocal meiotic recombination, 0030261=chromosome condensation, 0048477=oogenesis, 0009949=polarity specification of anterior/posterior axis" "Spn-B, Rad51, Spindle B, Spindle-B, Rad51-like, XRCC3, rad51-like, spnB, SpindleB, CG3325, spindle-B, SpnB" "IPR020588=DNA recombination and repair protein RecA-like, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013632=DNA recombination and repair protein Rad51, C-terminal" CG3325 16-Dec-15 2015_12 ENSDARG00000017928(xrcc3) YDR004W(RAD57) ENSXETG00000023061(XRCC3) ENSMUSG00000021287(Xrcc3) ENSG00000126215(XRCC3) "wild-type,viable,radiation sensitive,female sterile,recessive,planar polarity defective" "dorsal appendage,egg,karyosome,synaptonemal complex,germline cyst,dorsal,oocyte,nurse cell,chorion | maternal effect,maternal effect,nuclear membrane & oocyte nucleus,oocyte nucleus,oocyte nucleus & meiotic cell cycle,presumptive oocyte" FBgn0023478 TfIIZ Transcription factor IIZ http://flybase.net/reports/FBgn0023478.html gene TFIIZ 16-Dec-15 2015_12 FBgn0001778 l(1)M60 lethal (1) M60 http://flybase.net/reports/FBgn0001778.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259375 C293 http://flybase.net/reports/FBgn0259375.html gene 16-Dec-15 2015_12 visible "wing hair,wing,wing vein,chaeta" FBgn0037534 CG2781 http://flybase.net/reports/FBgn0037534.html protein_coding_gene "0003843=1,3-beta-D-glucan synthase activity, 0009922=fatty acid elongase activity" 0030497=fatty acid elongation 0016021=integral component of membrane IPR002076=ELO family CG2781 16-Dec-15 2015_12 "ENSDARG00000005785(elovl7b),ENSDARG00000069279(elovl7a),ENSDARG00000058356(elovl1b),ENSDARG00000002412(elovl1a)" "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "ENSXETG00000009581(ELOVL1),ENSXETG00000016688(elovl7)" "ENSMUSG00000021696(Elovl7),ENSMUSG00000006390(Elovl1)" "ENSG00000164181(ELOVL7),ENSG00000066322(ELOVL1)" lethal FBgn0036974 eRF1 eukaryotic release factor 1 http://flybase.net/reports/FBgn0036974.html "FBgn0010710, FBgn0011462" protein_coding_gene "0016149=translation release factor activity, codon specific, 0003747=translation release factor activity, 0008079=translation termination factor activity" "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0007224=smoothened signaling pathway, 0006415=translational termination, 0006605=protein targeting" "0005829=cytosol, 0005737=cytoplasm, 0018444=translation release factor complex" "l(3)05637, l(3)00103, Dm0184, Eukaryotic release factor 1, group J, Group J, CG5605, l(3)neo28, l(3)77ABb" "IPR005141=eRF1 domain 2, IPR005140=eRF1 domain 1/Pelota-like, IPR024049=Peptide Chain Release Factor eRF1/aRF1, N-terminal, IPR004403=Peptide chain release factor eRF1/aRF1, IPR029064=50S ribosomal protein L30e-like, IPR005142=eRF1 domain 3" CG5605 16-Dec-15 2015_12 ENSDARG00000043976(etf1) YBR143C(SUP45) WBGene00020269(T05H4.6a) ENSXETG00000011876(etf1) ENSMUSG00000024360(Etf1) ENSG00000120705(ETF1) "lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage,cell lethalcell lethal,somatic clone" "dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell" DRSC11779 E -0.129932628 0.027598073 1.384228708 -2.087196174 0.528971465 1.035170051 FBgn0004558 Su(var)307 Suppressor of variegation 307 http://flybase.net/reports/FBgn0004558.html gene 307 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0003208 gua1 guanosine 1 http://flybase.net/reports/FBgn0003208.html gene "guanosine requiring, l(1)H25, l(1)J5, l(1)D12, l(1)F19, gua1-1, l(1)RC1, l(1)H6, l(1)EA140, l(1)N23, gua1-1[ts], l(1)E6, gua-1, l(1)K27, l(1)S27, l(1)DC819, l(1)F1" 16-Dec-15 2015_12 "auxotroph,heat sensitive" FBgn0065730 l(2)SH0555 lethal (2) SH0555 http://flybase.net/reports/FBgn0065730.html gene l(2)SH2 0555 16-Dec-15 2015_12 "lethal,recessive" FBgn0263879 l(3)PL13 http://flybase.net/reports/FBgn0263879.html gene 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage" "embryonic/larval neuroblast,embryonic/larval brain,embryonic/larval optic lobe" FBgn0050225 tRNA:CR30225 transfer RNA:CR30225 http://flybase.net/reports/FBgn0050225.html "FBgn0012008, FBgn0060028" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033449=GUU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002787.trna51-ValAAC, transfer RNA:val4:56D, tRNA:V4:56D, CR30225, tRNA:V:AAC:AE002787-a, valine tRNA, chr2R.trna34-ValAAC, tRNA:val4:56D, tRNA[Val-AAC], tRNA[Val][[4]]" CR30225 16-Dec-15 2015_12 FBgn0035068 CG12849 http://flybase.net/reports/FBgn0035068.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG12849 16-Dec-15 2015_12 viable FBgn0037536 CG2698 http://flybase.net/reports/FBgn0037536.html protein_coding_gene IPR002549=Uncharacterised protein family UPF0118 CG2698 16-Dec-15 2015_12 ENSDARG00000070455(LOC100000119) WBGene00010810(M01F1.4) ENSMUSG00000055296(D730040F13Rik) ENSG00000106771(C9orf5) "viable,fertile" FBgn0260499 qvr quiver http://flybase.net/reports/FBgn0260499.html "FBgn0014377, FBgn0053472, FBgn0050032, FBgn0062504, FBgn0066054" protein_coding_gene 0034235=GPI anchor binding "0045837=negative regulation of membrane potential, 0032222=regulation of synaptic transmission, cholinergic, 1903049=negative regulation of acetylcholine-gated cation channel activity, 0030431=sleep, 0045938=positive regulation of circadian sleep/wake cycle, sleep" "0009897=external side of plasma membrane, 0008076=voltage-gated potassium channel complex" "CG30032, BcDNA:GH06755, anon-WO02059370.1, CG33472, sleepless, mdcds_22455, SLEEPLESS, sss" CG33472 16-Dec-15 2015_12 FBgn0033086 CG9410 http://flybase.net/reports/FBgn0033086.html protein_coding_gene 0005743=mitochondrial inner membrane "IPR023393=START-like domain, IPR005031=Coenzyme Q-binding protein COQ10, START domain" CG9410 16-Dec-15 2015_12 "ENSDARG00000056141(coq10b),ENSDARG00000070393(wu:fa99e11),ENSDARG00000009040(zgc:73324)" YOL008W(COQ10) WBGene00044648(R144.13) "ENSXETG00000009505(COQ10A),ENSXETG00000012036(TEgg051i04.1)" "ENSMUSG00000025981(Coq10b),ENSMUSG00000039914(Coq10a)" "ENSG00000115520(COQ10B),ENSG00000135469(COQ10A)" viable FBgn0060310 l(3)S147915d lethal (3) S147915d http://flybase.net/reports/FBgn0060310.html gene 1479/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0263897 l(3)A11 http://flybase.net/reports/FBgn0263897.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0263483 snoRNA:lola-d http://flybase.net/reports/FBgn0263483.html snoRNA_gene chr2R:6048993..6049090 CR43598 16-Dec-15 2015_12 FBgn0261600 M(3)98B Minute (3) 98B http://flybase.net/reports/FBgn0261600.html gene 16-Dec-15 2015_12 FBgn0005440 l(1)v132 lethal (1) v132 http://flybase.net/reports/FBgn0005440.html gene l(1)132 16-Dec-15 2015_12 FBgn0039804 CG15544 http://flybase.net/reports/FBgn0039804.html protein_coding_gene CG15544 16-Dec-15 2015_12 viable FBgn0065960 l(2)SH0037 lethal (2) SH0037 http://flybase.net/reports/FBgn0065960.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002027 l(2)37Bi lethal (2) 37Bi http://flybase.net/reports/FBgn0002027.html gene "Bi, l(2)E131" 16-Dec-15 2015_12 lethal FBgn0031247 CG11562 http://flybase.net/reports/FBgn0031247.html FBgn0063011 protein_coding_gene 0005739=mitochondrion BcDNA:RE44650 CG11562 16-Dec-15 2015_12 lethal FBgn0001430 l(1)6Fc lethal (1) 6Fc http://flybase.net/reports/FBgn0001430.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0065152 l(3)SH065 lethal (3) SH065 http://flybase.net/reports/FBgn0065152.html gene l(2)SH3 065 16-Dec-15 2015_12 "lethal,recessive" FBgn0051469 CG31469 http://flybase.net/reports/FBgn0051469.html "FBgn0038174, FBgn0063632" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0098627=protein arginine phosphatase activity" "0098628=peptidyl-N-phospho-arginine dephosphorylation, 0006470=protein dephosphorylation" "0005737=cytoplasm, 0070062=extracellular exosome" CG9599 "IPR017867=Protein-tyrosine phosphatase, low molecular weight, IPR023485=Phosphotyrosine protein phosphatase I superfamily" CG31469 16-Dec-15 2015_12 "ENSDARG00000070328(acp1),ENSDARG00000003891(LOC100330515)" viable FBgn0035844 CG13676 http://flybase.net/reports/FBgn0035844.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13676 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0022104 l(2)k07110 lethal (2) k07110 http://flybase.net/reports/FBgn0022104.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0262167 ana1 anastral spindle 1 http://flybase.net/reports/FBgn0262167.html "FBgn0039206, FBgn0043880" protein_coding_gene "0007052=mitotic spindle organization, 0048666=neuron development, 0030317=sperm motility, 0060271=cilium morphogenesis, 0007288=sperm axoneme assembly, 0051297=centrosome organization, 0051298=centrosome duplication, 0032053=ciliary basal body organization, 0050954=sensory perception of mechanical stimulus, 0007099=centriole replication" "0036064=ciliary basal body, 0005814=centriole" "mechanosensory B, Ana1, Ana 1, anastral spindle phenotype 1, CG6631, mechanosensory mutant B, Ana-1, mecB" CG6631 16-Dec-15 2015_12 "uncoordinated,temperature conditional" "centrosome,mechanosensory neuron,cilium,microtubule basal body,spermatid axoneme,spermatozoon" FBgn0015502 l(3)65CEf lethal (3) 65CEf http://flybase.net/reports/FBgn0015502.html gene "XV, Distal W5.4 Group XV" 16-Dec-15 2015_12 lethal FBgn0044098 E(rst)C7 E(rst)C7 http://flybase.net/reports/FBgn0044098.html gene 0001745=compound eye morphogenesis C7 16-Dec-15 2015_12 FBgn0065332 l(2)SH1871 lethal (2) SH1871 http://flybase.net/reports/FBgn0065332.html gene l(2)SH2 1871 16-Dec-15 2015_12 "lethal,recessive" FBgn0061118 l(3)S005302b lethal (3) S005302b http://flybase.net/reports/FBgn0061118.html gene 0053/02 16-Dec-15 2015_12 FBgn0023506 Es2 Es2 http://flybase.net/reports/FBgn0023506.html protein_coding_gene 0004757=sepiapterin reductase activity "0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0071013=catalytic step 2 spliceosome" "es, CG1474, ES2" IPR019148=Nuclear protein DGCR14 CG1474 16-Dec-15 2015_12 ENSDARG00000060922(zgc:162979) WBGene00018371(ess-2) ENSXETG00000022387(DGCR14) ENSMUSG00000003527(Dgcr14) ENSG00000100056(DGCR14) "partially lethal - majority die,some die during pupal stage" FBgn0052442 CG32442 http://flybase.net/reports/FBgn0052442.html "FBgn0047079, FBgn0064837" protein_coding_gene "BcDNA:RE62711, BcDNA:RH17480" IPR007290=Arv1 protein CG32442 16-Dec-15 2015_12 YLR242C(ARV1) ENSXETG00000026359(ARV1) ENSMUSG00000031982(Arv1) ENSG00000173409(ARV1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037152 CG15374 http://flybase.net/reports/FBgn0037152.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031717 Oscillin Oscillin http://flybase.net/reports/FBgn0031717.html protein_coding_gene 0004342=glucosamine-6-phosphate deaminase activity "0006043=glucosamine catabolic process, 0006091=generation of precursor metabolites and energy, 0006044=N-acetylglucosamine metabolic process, 0005975=carbohydrate metabolic process" 0005737=cytoplasm "oscillin, CG6957" "IPR004547=Glucosamine-6-phosphate isomerase, IPR018321=Glucosamine-6-phosphate isomerase, conserved site, IPR006148=Glucosamine/galactosamine-6-phosphate isomerase" CG6957 16-Dec-15 2015_12 "ENSDARG00000024443(LOC556291),ENSDARG00000037307(gnpda1)" WBGene00011399(T03F6.3) ENSXETG00000004172(GNPDA1) "ENSMUSG00000029209(Gnpda2),ENSMUSG00000052102(Gnpda1)" "ENSG00000163281(GNPDA2),ENSG00000113552(GNPDA1)" FBgn0069354 Porin2 Porin2 http://flybase.net/reports/FBgn0069354.html "FBgn0032308, FBgn0046236" protein_coding_gene "0008308=voltage-gated anion channel activity, 0015288=porin activity, 0005261=cation channel activity" "0006839=mitochondrial transport, 0006811=ion transport, 0044070=regulation of anion transport, 0055085=transmembrane transport" "0005739=mitochondrion, 0005741=mitochondrial outer membrane" "LP07660.3prime, Porin 2, DmPorin2, CG17137, porin 2, BEST:LP07660, porin2" "IPR027246=Eukaryotic porin/Tom40, IPR001925=Porin, eukaryotic type, IPR023614=Porin domain" CG17137 16-Dec-15 2015_12 "YNL055C(POR1),YIL114C(POR2)" WBGene00019900(R05G6.7) viable FBgn0264506 CR43905 http://flybase.net/reports/FBgn0264506.html non_protein_coding_gene CR43905 16-Dec-15 2015_12 FBgn0034709 Swim Secreted Wg-interacting molecule http://flybase.net/reports/FBgn0034709.html protein_coding_gene "0004197=cysteine-type endopeptidase activity, 0005044=scavenger receptor activity, 0030247=polysaccharide binding, 0017147=Wnt-protein binding" "0030177=positive regulation of Wnt signaling pathway, 0035593=positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region, 0006508=proteolysis, 0006955=immune response" "0042600=chorion, 0005615=extracellular space" "dead man walking, CG3074, dmw, swim" "IPR025660=Cysteine peptidase, histidine active site, IPR001212=Somatomedin B domain, IPR000668=Peptidase C1A, papain C-terminal, IPR013128=Peptidase C1A, IPR025661=Cysteine peptidase, asparagine active site" CG3074 16-Dec-15 2015_12 ENSDARG00000061231(si:dkey-158b13.1) WBGene00009158(F26E4.3) ENSXETG00000017634(TINAGL1) "ENSMUSG00000028776(Tinagl1),ENSMUSG00000032357(Tinag)" "ENSG00000142910(TINAGL1),ENSG00000137251(TINAG)" "partially lethal - majority die,visible,viable,fertile" wing margin FBgn0064183 frag fragmented mitochondria http://flybase.net/reports/FBgn0064183.html gene 0007005=mitochondrion organization 16-Dec-15 2015_12 FBgn0031371 CG15363 http://flybase.net/reports/FBgn0031371.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035877 CG7083 http://flybase.net/reports/FBgn0035877.html protein_coding_gene IPR005373=Uncharacterised protein family UPF0183 CG7083 16-Dec-15 2015_12 ENSDARG00000041560(si:dkey-102f14.5) WBGene00011344(T01G9.2) ENSMUSG00000031889(D230025D16Rik) ENSG00000125149(C16orf70) viable FBgn0052718 CG32718 http://flybase.net/reports/FBgn0052718.html protein_coding_gene CG32718 16-Dec-15 2015_12 FBgn0267529 CR45869 http://flybase.net/reports/FBgn0267529.html non_protein_coding_gene CR45869 16-Dec-15 2015_12 FBgn0265827 CR44616 http://flybase.net/reports/FBgn0265827.html non_protein_coding_gene lincRNA.84 CR44616 16-Dec-15 2015_12 FBgn0261054 Sfp24Bc Seminal fluid protein 24Bc http://flybase.net/reports/FBgn0261054.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space SFP24BC "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG42602 16-Dec-15 2015_12 FBgn0033209 CG12107 http://flybase.net/reports/FBgn0033209.html protein_coding_gene "IPR029008=Rab5-interacting protein family, IPR010742=Rab5-interacting protein" CG12107 16-Dec-15 2015_12 WBGene00018431(F44E7.9) "ENSXETG00000019460(BC091613.1),ENSXETG00000003118()" ENSMUSG00000027637(1110008F13Rik) viable FBgn0028255 l(3)79Ba lethal (3) 79Ba http://flybase.net/reports/FBgn0028255.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0263032 CG43327 http://flybase.net/reports/FBgn0263032.html "FBgn0045218, FBan0030459, FBgn0050459" protein_coding_gene CG30459 CG43327 16-Dec-15 2015_12 FBgn0039633 CG11873 http://flybase.net/reports/FBgn0039633.html FBgn0044716 protein_coding_gene 0034976=response to endoplasmic reticulum stress anon-WO0140519.162 "IPR015671=GLTSCR protein, conserved region" CG11873 16-Dec-15 2015_12 ENSDARG00000061159(gltscr1) ENSMUSG00000070808(Gltscr1) ENSG00000112624(KIAA0240) lethal DRSC14417 E 0.964884036 -0.048324331 2.416082893 0.264860267 0.852290489 1.292673771 FBgn0030739 SWIP http://flybase.net/reports/FBgn0030739.html protein_coding_gene 0071203=WASH complex "CG13957, p116" "IPR028191=WASH complex subunit 7, N-terminal, IPR028283=WASH complex subunit 7, C-terminal, IPR028282=WASH complex subunit 7, central domain, IPR027307=WASH complex subunit 7" CG13957 16-Dec-15 2015_12 ENSDARG00000061719(LOC565752) WBGene00013167(Y53F4B.21) ENSXETG00000001887(KIAA1033) ENSMUSG00000034560(A230046K03Rik) ENSG00000136051(KIAA1033) viable FBgn0050039 CG30039 http://flybase.net/reports/FBgn0050039.html "FBgn0045189, FBgn0045288, FBgn0063352" protein_coding_gene "NEST:bs25c07, NEST:bs15e10, BcDNA:AT09538" CG30039 16-Dec-15 2015_12 viable FBgn0262384 mir-1014 mir-1014 stem loop http://flybase.net/reports/FBgn0262384.html "FBgn0250810, FBgn0262202" miRNA_gene "miR-1014, CR42909, dme-mir-1014" CR42909 16-Dec-15 2015_12 viable FBgn0016717 Reg-21 Rhythmically expressed gene 21 http://flybase.net/reports/FBgn0016717.html gene "Drosophila Rhythmically expressed gene 21, Dreg-21" 16-Dec-15 2015_12 adult stage adult head

FBgn0259700 CG42354 http://flybase.net/reports/FBgn0259700.html "FBan0009216, FBgn0030726" protein_coding_gene CG9216 CG42354 16-Dec-15 2015_12 FBgn0266256 CR44951 http://flybase.net/reports/FBgn0266256.html non_protein_coding_gene lincRNA.860 CR44951 16-Dec-15 2015_12 FBgn0002228 l(3)68Bg lethal (3) 68Bg http://flybase.net/reports/FBgn0002228.html gene "l(3)L, l(3)C11" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" FBgn0037493 CG10032 http://flybase.net/reports/FBgn0037493.html protein_coding_gene "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000436=Sushi/SCR/CCP domain" CG10032 16-Dec-15 2015_12 FBgn0034053 Cyp4aa1 Cyp4aa1 http://flybase.net/reports/FBgn0034053.html protein_coding_gene "0005506=iron ion binding, 0004497=monooxygenase activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" "0055114=oxidation-reduction process, 0046701=insecticide catabolic process, 0042445=hormone metabolic process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG8302, cytochrome P450, 4aa1, Cyp4AA1" "IPR001128=Cytochrome P450, IPR002403=Cytochrome P450, E-class, group IV, IPR017972=Cytochrome P450, conserved site" CG8302 16-Dec-15 2015_12 YMR015C(ERG5) FBgn0052739 CR32739 http://flybase.net/reports/FBgn0052739.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0003709 tipD temperature-induced paralytic D http://flybase.net/reports/FBgn0003709.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0004892 sob sister of odd and bowl http://flybase.net/reports/FBgn0004892.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0016348=imaginal disc-derived leg joint morphogenesis, 0006909=phagocytosis" 0005634=nucleus "Sob, org1, odd skipped-related 1, CG3242" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG3242 16-Dec-15 2015_12 "ENSMUSG00000000317(Bcl6b),ENSMUSG00000020453(Patz1),ENSMUSG00000066687(Zbtb16),ENSMUSG00000044646(Zbtb7c)" ENSG00000162676(GFI1) " embryonic stage | stage 5 , embryonic stage | stage >=6 , embryonic stage | late , pupal stage , larval stage | third instar " " organism | pair rule

,

segment polarity , Malpighian tubule

, embryonic brain

, embryonic/larval proventriculus

, leg | restricted

, organism | 90-100% egg length

, ventral thoracic disc | restricted

, pharyngeal muscle

" visible "leg & adult cuticleptc-559.1,ventral thoracic disc,tarsal segment,sex comb,ectopic" DRSC00838 K 0.075971856 1.073307477 -0.441114411 -0.257540673 0.370294197 1.581410602 FBgn0013658 ms(2)neo3 ms(2)neo3 http://flybase.net/reports/FBgn0013658.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0010552 l(2)03728 lethal (2) 03728 http://flybase.net/reports/FBgn0010552.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265714 CG44521 http://flybase.net/reports/FBgn0265714.html protein_coding_gene CG44521 16-Dec-15 2015_12 FBgn0259582 GG01048 http://flybase.net/reports/FBgn0259582.html gene 16-Dec-15 2015_12 visible leg FBgn0015698 E(var)5 Enhancer of variegation 5 http://flybase.net/reports/FBgn0015698.html gene 16-Dec-15 2015_12 FBgn0031132 CG15450 http://flybase.net/reports/FBgn0031132.html protein_coding_gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity 0008152=metabolic process IPR002123=Phospholipid/glycerol acyltransferase CG15450 16-Dec-15 2015_12 "ENSDARG00000016048(LOC100332631),ENSDARG00000006491(agpat9l),ENSDARG00000019897(zgc:136875)" "ENSXETG00000016807(AGPAT6),ENSXETG00000001828(AGPAT9)" "ENSMUSG00000029314(Agpat9),ENSMUSG00000031545(Agpat6)" viable FBgn0062621 Mod(var)1173 Mod(var)1173 http://flybase.net/reports/FBgn0062621.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1173 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0015489 l(2)46Cm lethal (2) 46Cm http://flybase.net/reports/FBgn0015489.html gene "Complementation group U, U" 16-Dec-15 2015_12 "lethal,recessive" FBgn0060956 l(3)S034107b lethal (3) S034107b http://flybase.net/reports/FBgn0060956.html gene 0341/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262775 Su(E1)-I http://flybase.net/reports/FBgn0262775.html gene 16-Dec-15 2015_12 FBgn0026674 l(1)G0115 lethal (1) G0115 http://flybase.net/reports/FBgn0026674.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0058235 CG40235 http://flybase.net/reports/FBgn0058235.html protein_coding_gene 16-Dec-15 2015_12 FBgn0010048 Hirsute Hirsute http://flybase.net/reports/FBgn0010048.html gene Hi 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "eye,ommatidium,macrochaeta" FBgn0038809 CG16953 http://flybase.net/reports/FBgn0038809.html protein_coding_gene CG16953 16-Dec-15 2015_12 "viable,fertile" FBgn0021958 l(2)k10210 lethal (2) k10210 http://flybase.net/reports/FBgn0021958.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038344 CG5205 http://flybase.net/reports/FBgn0038344.html protein_coding_gene "0005524=ATP binding, 0003724=RNA helicase activity, 0004386=helicase activity, 0003676=nucleic acid binding" "0000398=mRNA splicing, via spliceosome" "0005682=U5 snRNP, 0030532=small nuclear ribonucleoprotein complex" cg5205 "IPR014756=Immunoglobulin E-set, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR000008=C2 domain, IPR003593=AAA+ ATPase domain, IPR004179=Sec63 domain, IPR001650=Helicase, C-terminal" CG5205 16-Dec-15 2015_12 YGR271W(SLH1) WBGene00013189(Y54E2A.4) ENSMUSG00000038774(Ascc3) ENSG00000112249(ASCC3) viable FBgn0260855 Sec22 Sec22 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0260855.html "FBgn0025617, FBgn0044820" protein_coding_gene 0005484=SNAP receptor activity "0006906=vesicle fusion, 0006890=retrograde vesicle-mediated transport, Golgi to ER, 0006909=phagocytosis, 0006888=ER to Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport" "0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0012507=ER to Golgi transport vesicle membrane, 0031201=SNARE complex, 0000139=Golgi membrane, 0030133=transport vesicle" "SEC22, CG7359, EG:34F3.8, 34F3.8, Sec22p, Sec22" "IPR011012=Longin-like domain, IPR010908=Longin domain, IPR001388=Synaptobrevin" CG7359 16-Dec-15 2015_12 "ENSDARG00000005887(sec22bb),ENSDARG00000068285,ENSDARG00000069284,ENSDARG00000030108(sec22ba)" YLR268W(SEC22) WBGene00018853(sec-22) ENSXETG00000025777(sec22l1) ENSMUSG00000027879(Sec22b) DRSC29297 EK -0.999714792 -1.366519866 -1.850992771 -0.058931736 0.248069619 1.540368177 FBgn0002972 nuc1 nucleoside auxotroph 1 http://flybase.net/reports/FBgn0002972.html gene "pyr2-1, pyr2-2, pyrimidine-2.1, pyrimidine-2-2" 16-Dec-15 2015_12 "auxotroph,recessive,maternal effect,fertile" FBgn0262613 CG43139 http://flybase.net/reports/FBgn0262613.html protein_coding_gene DMG4-MB6.chr3R.40.017 CG43139 16-Dec-15 2015_12 FBgn0036088 CG14152 http://flybase.net/reports/FBgn0036088.html protein_coding_gene CT33755 16-Dec-15 2015_12 FBgn0069344 T:nls-tra nuclear localisation signal of tra http://flybase.net/reports/FBgn0069344.html engineered_tag "T:nls5, nuclear localisation signal 5" 16-Dec-15 2015_12 FBgn0264363 CG43815 http://flybase.net/reports/FBgn0264363.html protein_coding_gene CG43815 16-Dec-15 2015_12 FBgn0020843 l(2)21Be lethal (2) 21Be http://flybase.net/reports/FBgn0020843.html gene 21Be 16-Dec-15 2015_12 FBgn0038989 CG6937 http://flybase.net/reports/FBgn0038989.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" 0022008=neurogenesis cg6937 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG6937 16-Dec-15 2015_12 ENSDARG00000040666(mki67ip) WBGene00011408(T04A8.6) ENSMUSG00000026377(Mki67ip) ENSG00000155438(MKI67IP) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC16140 I -1.747777868 -0.626960932 -0.016507862 0.346426373 0.844744892 0.146825109 FBgn0011468 l(3)neo35 lethal (3) neo35 http://flybase.net/reports/FBgn0011468.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0052035 CG32035 http://flybase.net/reports/FBgn0052035.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053710 CG33710 http://flybase.net/reports/FBgn0053710.html FBgn0045417 protein_coding_gene "bs03f11.y1, NEST:bs03f11" CG33710 16-Dec-15 2015_12 viable FBgn0000617 e(y)1 enhancer of yellow 1 http://flybase.net/reports/FBgn0000617.html "FBgn0000620, FBgn0011302" protein_coding_gene "0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0004402=histone acetyltransferase activity" "0007221=positive regulation of transcription of Notch receptor target, 0043966=histone H3 acetylation, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter" "0005669=transcription factor TFIID complex, 0090575=RNA polymerase II transcription factor complex, 0005634=nucleus, 0000124=SAGA complex" "dTAF[[40]], TAF[[II]], TAF[II]40, dTAF[[II]]42, taf40/e(y)1, p42, TFIID 42, Taf42, Taf[[II]]40, enhancer of yellow 4, e(y)[1], TAFII40, dTAF[[II]]40, TBP-associated factor 40kD, dmTaf9, Taf9, dmTAF9, dTAFII42, TFIID, TAF9, dTAF42, dme-TAFII40, TAF40/42, TAF40/42/e(y)1, TAF[[II]]42, CG6474, TAF[[II]]40, TAF42, TFIID-p42, e(y)4, TBP-associated factor, d40, dTAF9, Taf40, TAF40, E(y)1, TAFII40(42), TAF[[II]]40/42" "IPR009072=Histone-fold, IPR003162=Transcription initiation factor TAFII31" CG6474 16-Dec-15 2015_12 ENSDARG00000060640(taf9) WBGene00006391(taf-9) ENSXETG00000010138() "ENSMUSG00000047242(Taf9b),ENSMUSG00000052293(Taf9)" "ENSG00000187325(TAF9B),ENSG00000215760,ENSG00000085231(TAF9)" "female sterile,recessive,viable,visible,male,female fertile,wild-type" "ovary,oocyte,macrochaeta" DRSC25903 IK -1.580826258 1.844344247 -0.891277819 1.112974895 0.590057902 2.356003602 FBgn0033364 CG13747 http://flybase.net/reports/FBgn0033364.html protein_coding_gene dmCG13747 CG13747 16-Dec-15 2015_12 viable FBgn0259257 C76 http://flybase.net/reports/FBgn0259257.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin,chaeta,ectopic" FBgn0017448 CG2187 http://flybase.net/reports/FBgn0017448.html protein_coding_gene 0008507=sodium:iodide symporter activity 0055085=transmembrane transport 0016020=membrane "dSLC5A6, anon-100EF-D3, D3-100EF" "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG2187 16-Dec-15 2015_12 YHL016C(DUR3) "partially lethal - majority die,some die during pupal stage" FBgn0036362 CG10725 http://flybase.net/reports/FBgn0036362.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG10725 16-Dec-15 2015_12 viable FBgn0023514 CG14805 http://flybase.net/reports/FBgn0023514.html protein_coding_gene "EG:63B12.7, i207" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR019775=WD40 repeat, conserved site" CG14805 16-Dec-15 2015_12 ENSDARG00000041113(wdr18) WBGene00004185(pro-1) ENSXETG00000021612(wdr18) ENSMUSG00000035754(Wdr18) ENSG00000065268(WDR18) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0064174 l(2)T32 lethal (2) T32 http://flybase.net/reports/FBgn0064174.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0046652 anon-38D.12 anon-38D.12 http://flybase.net/reports/FBgn0046652.html gene 38D.12 16-Dec-15 2015_12 FBgn0031682 CG5828 http://flybase.net/reports/FBgn0031682.html protein_coding_gene 0004594=pantothenate kinase activity 0015937=coenzyme A biosynthetic process "0005634=nucleus, 0005737=cytoplasm" "IPR016949=Uncharacterised conserved protein UCP030210, IPR002791=Domain of unknown function DUF89" CG5828 16-Dec-15 2015_12 ENSXETG00000012083(PANK4) viable FBgn0086390 BG01909 http://flybase.net/reports/FBgn0086390.html gene "0002121=inter-male aggressive behavior, 0042048=olfactory behavior" 16-Dec-15 2015_12 "viable,smell perception defective,behavior defective,recessive" FBgn0031517 CG15406 http://flybase.net/reports/FBgn0031517.html protein_coding_gene 0005353=fructose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG15406 16-Dec-15 2015_12 "viable,fertile" FBgn0050187 CG30187 http://flybase.net/reports/FBgn0050187.html FBgn0062884 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis BcDNA:SD12357 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG30187 16-Dec-15 2015_12 viable FBgn0030331 CG15221 http://flybase.net/reports/FBgn0030331.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG15221 16-Dec-15 2015_12 viable FBgn0005030 ef elfin http://flybase.net/reports/FBgn0005030.html gene 16-Dec-15 2015_12 "viable,male sterile,visible,male,body color defective" "wing,adult thorax,adult abdomen,tergite" FBgn0262886 CR43241 http://flybase.net/reports/FBgn0262886.html non_protein_coding_gene lincRNA.229 CR43241 16-Dec-15 2015_12 FBgn0002634 ma maroon http://flybase.net/reports/FBgn0002634.html gene 16-Dec-15 2015_12 eye color defective "pigment cell,Malpighian tubule" FBgn0063387 snoRNA:U27:54Eb snoRNA:U27:54Eb http://flybase.net/reports/FBgn0063387.html snoRNA_gene "Dm_18S.009, U27snoRNA, Dm_18S.011, DmSnR74/Z4, CR32900" CR32900 16-Dec-15 2015_12 FBgn0267021 CR45465 http://flybase.net/reports/FBgn0267021.html non_protein_coding_gene CR45465 16-Dec-15 2015_12 FBgn0033528 trsn translin http://flybase.net/reports/FBgn0033528.html protein_coding_gene "0004521=endoribonuclease activity, 0043565=sequence-specific DNA binding, 0003677=DNA binding" "0016246=RNA interference, 0050821=protein stabilization, 0007630=jump response" "0005634=nucleus, 0005737=cytoplasm" "testis-brain RNA binding protein, CG11761, Translin, translin, TRANSLIN, TB-RBP" "IPR016068=Translin, N-terminal, IPR016069=Translin, C-terminal, IPR002848=Translin" CG11761 16-Dec-15 2015_12 ENSDARG00000041830(zgc:123170) ENSXETG00000000838(tsn) ENSMUSG00000026374(Tsn) ENSG00000211460(TSN) "viable,fertile,jump response defective,recessive" FBgn0024283 Su(hh)3A Suppressor of hedgehog 3A http://flybase.net/reports/FBgn0024283.html gene 0035214=eye-antennal disc development S(hh)3A 16-Dec-15 2015_12 FBgn0266944 CR45395 http://flybase.net/reports/FBgn0266944.html non_protein_coding_gene lincRNA.571 CR45395 16-Dec-15 2015_12 FBgn0025886 ms(3)2033 ms(3)2033 http://flybase.net/reports/FBgn0025886.html gene TW-ms(3)2033 16-Dec-15 2015_12 male sterile FBgn0003083 pi pied http://flybase.net/reports/FBgn0003083.html gene pi 16-Dec-15 2015_12 "male sterile,visible,viable,reduced" "eye,ommatidium,wing,genitalia,male" FBgn0264495 gpp grappa http://flybase.net/reports/FBgn0264495.html "FBgn0261972, FBgn0014963, FBgn0010795, FBgn0011041, FBgn0037444, FBgn0046759, FBgn0062097, FBgn0053324, FBgn0060693" protein_coding_gene 0031151=histone methyltransferase activity (H3-K79 specific) "2000637=positive regulation of gene silencing by miRNA, 0006342=chromatin silencing, 0046331=lateral inhibition, 0051726=regulation of cell cycle, 0034729=histone H3-K79 methylation" 0005634=nucleus "BcDNA:SD05230, 0732/14, CG33324, lethal (3) S073214b, anon-WO0118547.319, Gpp, dDot1, l(3)sA3484, CG10272, grp, CG42803, DOT1L, l(3)03342, Grappa, l(3)S073214b, dDOT1L" "IPR030445=Histone H3-K79 methyltransferase, IPR025789=Histone-lysine N-methyltransferase DOT1 domain, IPR021169=Histone H3-K79 methyltransferase, metazoa, IPR013110=Histone methylation DOT1, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG42803 16-Dec-15 2015_12 ENSDARG00000061992(dot1l) ENSXETG00000013658(DOT1L) ENSMUSG00000061589(Dot1l) ENSG00000104885(DOT1L) FBgn0045055 fs(1)192 female sterile (1) 192 http://flybase.net/reports/FBgn0045055.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "ovary,egg" FBgn0061189 Ubx::Afra\Ubx Ubx http://flybase.net/reports/FBgn0061189.html engineered_fusion_gene 16-Dec-15 2015_12 Keilin's organ FBgn0031590 CG3702 http://flybase.net/reports/FBgn0031590.html protein_coding_gene "0016021=integral component of membrane, 0012505=endomembrane system" cg3702 IPR008429=Cleft lip and palate transmembrane 1 CG3702 16-Dec-15 2015_12 ENSDARG00000018973(clptm1) "WBGene00011302(R166.2),WBGene00016469(C36B7.6)" ENSMUSG00000002981(Clptm1) ENSG00000104853(CLPTM1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014167 fs(1)2Ca fs(1)2Ca http://flybase.net/reports/FBgn0014167.html gene unnamed 16-Dec-15 2015_12 "egg chamber,egg" FBgn0004390 RasGAP1 Ras GTPase activating protein 1 http://flybase.net/reports/FBgn0004390.html FBgn0005621 protein_coding_gene 0005096=GTPase activator activity "0008595=anterior/posterior axis specification, embryo, 0007426=tracheal outgrowth, open tracheal system, 0016321=female meiosis chromosome segregation, 0043547=positive regulation of GTPase activity, 0007476=imaginal disc-derived wing morphogenesis, 0022008=neurogenesis, 0007265=Ras protein signal transduction, 0007062=sister chromatid cohesion, 0045678=positive regulation of R7 cell differentiation, 0007067=mitotic nuclear division, 0008293=torso signaling pathway, 0046580=negative regulation of Ras protein signal transduction" "0031235=intrinsic component of the cytoplasmic side of the plasma membrane, 0005886=plasma membrane, 0005737=cytoplasm" "seven extra, more inner photoreceptors, gap, Gap1, GTPase-activating protein 1, Gap, rasGAP, GAP1, GTPase activating protein1, gap1, Ras-GAP, sxt, rI533, CG6721, sextra, RasGAP, GAP, mip, Gap 1, GTPase activating protein 1" "IPR001936=Ras GTPase-activating protein, IPR001849=Pleckstrin homology domain, IPR023152=Ras GTPase-activating protein, conserved site, IPR000008=C2 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001562=Zinc finger, Btk motif, IPR008936=Rho GTPase activation protein" CG6721 16-Dec-15 2015_12 ENSDARG00000063371(si:ch211-129c2.7) "ENSXETG00000013833(RASA3),ENSXETG00000014755(RASA2)" "ENSMUSG00000031453(Rasa3),ENSMUSG00000032413(Rasa2)" "ENSG00000185989(RASA3),ENSG00000155903(RASA2)" larval stage | third instar " central nervous system | restricted

, photoreceptor cell | presumptive

, dorsal mesothoracic disc

, ventral thoracic disc

, cone cell

, eye-antennal disc

" "visible,recessive,viable,neuroanatomy defective,lethal,maternal effect,dominant,wild-type,meiotic cell cycle defective,partially lethal - majority die,mitotic cell cycle defective" "ommatidium,photoreceptor cell R7,cone cell,chordotonal organ,eye,rhabdomere,wing,wing sensillum,wing vein,primary pigment cell,secondary pigment cell,tertiary pigment cell,chorion,dorsal appendage,embryonic epidermis,maternal effect,bract,supernumerary,embryonic dorsal epidermis,somatic clone,sex comb,ectopic,prothoracic tibial bract,mesothoracic tibial bract,metathoracic tibial bract,dorsal air sac primordium,mitosis & nuclear chromosome,anaphase & condensed nuclear chromosome,nuclear chromosome,heart primordium,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,cell autonomous,stage 5 embryo,gastrula embryo" DRSC11172 IE 1.921989288 -0.213625818 4.509579961 0.007740226 1.053263025 0.861942993 FBgn0034601 CG4286 http://flybase.net/reports/FBgn0034601.html protein_coding_gene CG4286 16-Dec-15 2015_12 viable DRSC04459 K 0.012773364 -0.518099351 -0.364364869 -1.388530871 -1.557798038 -0.612219891 FBgn0065972 kali kali http://flybase.net/reports/FBgn0065972.html gene "0048813=dendrite morphogenesis, 0016319=mushroom body development" 16-Dec-15 2015_12 "neuroanatomy defective,somatic clone" "embryonic/larval mushroom body,somatic clone" FBgn0021764 sdk sidekick http://flybase.net/reports/FBgn0021764.html FBgn0064868 protein_coding_gene "0050931=pigment cell differentiation, 0042675=compound eye cone cell differentiation, 0046533=negative regulation of photoreceptor cell differentiation" "0098595=perivitelline space, 0005887=integral component of plasma membrane" "BcDNA:RE63453, BcDNA:LD22322, EG:BACR19J1.1, Sidekick, CT16627, CG5227" "IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG5227 16-Dec-15 2015_12 "ENSDARG00000060452(sdk2b),ENSDARG00000062854(zgc:171522)" WBGene00004371(rig-4) "ENSMUSG00000041592(Sdk2),ENSMUSG00000039683(Sdk1)" "ENSG00000069188(SDK2),ENSG00000146555(SDK1)" "visible,recessive,viable" "eye,photoreceptor,mystery cell,pigment cell,ommatidium,interommatidial bristle,lens,cone cell" FBgn0001567 l(1)20Ad lethal (1) 20Ad http://flybase.net/reports/FBgn0001567.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000018 abo abnormal oocyte http://flybase.net/reports/FBgn0000018.html FBgn0032323 protein_coding_gene 0003682=chromatin binding "0000122=negative regulation of transcription from RNA polymerase II promoter, 0048477=oogenesis" "0005634=nucleus, 0005700=polytene chromosome" "CG6093, Abo" "IPR019138=De-etiolated protein 1, Det1" CG6093 16-Dec-15 2015_12 ENSDARG00000006145(det1) ENSXETG00000007591(DET1) ENSMUSG00000030610(Det1) ENSG00000140543(DET1) "viable,fertile,lethal,maternal effect,recessive,rescuable maternal effect,female sterile,suppressor of variegation,dominant,non-suppressor of variegation" "extended germ band embryo,embryonic head,embryonic/first instar larval cuticle" FBgn0003001 op opaque http://flybase.net/reports/FBgn0003001.html gene 16-Dec-15 2015_12 "visible,viable,male,female,poor,male fertile,female fertile" wing FBgn0001212 hp humped http://flybase.net/reports/FBgn0001212.html gene 16-Dec-15 2015_12 visible "scutoscutellar suture,adult thorax,macrochaeta" FBgn0084112 E-3c7 Enhancer on chromosome 3-complementation group c http://flybase.net/reports/FBgn0084112.html gene E-3c 16-Dec-15 2015_12 "Minute,dominant,lethal,recessive,developmental rate defective" chaeta FBgn0060565 l(3)S096515b lethal (3) S096515b http://flybase.net/reports/FBgn0060565.html gene 0965/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0051669 tRNA:CR31669 transfer RNA:CR31669 http://flybase.net/reports/FBgn0051669.html FBgn0060108 tRNA_gene 0033428=CAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002638.trna4-GlnCTG, CR31669, tRNA:Q:CTG:AE002638-a, chr2L.trna37-GlnCTG" CR31669 16-Dec-15 2015_12 FBgn0019691 l(3)69Ah lethal (3) 69Ah http://flybase.net/reports/FBgn0019691.html gene l(3)69Aa 16-Dec-15 2015_12 lethal FBgn0264864 CR44055 http://flybase.net/reports/FBgn0264864.html non_protein_coding_gene CR44055 16-Dec-15 2015_12 FBgn0038631 CG7695 http://flybase.net/reports/FBgn0038631.html protein_coding_gene IPR002350=Kazal domain CG7695 16-Dec-15 2015_12 FBgn0014925 anon-72ABi anon-72ABi http://flybase.net/reports/FBgn0014925.html gene 16-Dec-15 2015_12 FBgn0015428 l(1)1Fh lethal (1) 1Fh http://flybase.net/reports/FBgn0015428.html gene 13-80 16-Dec-15 2015_12 "lethal,recessive" FBgn0053534 tRNA:CR33534 transfer RNA:CR33534 http://flybase.net/reports/FBgn0053534.html "FBgn0004263, FBgn0060287" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033453=GCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR33534, chr3R.trna18-AlaAGC, tRNA[[Ala]], tRNA:-?:90Cb, transfer RNA:?:90Cb, tRNA:A:AGC:AE002708-b, AE002708.trna12-AlaAGC" CR33534 16-Dec-15 2015_12 FBgn0034858 eIF2B-ë« eIF2B-ë« http://flybase.net/reports/FBgn0034858.html protein_coding_gene "0003743=translation initiation factor activity, 0005085=guanyl-nucleotide exchange factor activity, 0046523=S-methyl-5-thioribose-1-phosphate isomerase activity" "0045947=negative regulation of translational initiation, 0022008=neurogenesis, 0006446=regulation of translational initiation, 0019509=L-methionine biosynthetic process from methylthioadenosine, 0006413=translational initiation" "0005851=eukaryotic translation initiation factor 2B complex, 0005829=cytosol, 0005737=cytoplasm" "CG10315, eIF2Bdelta, eIF2B-delta" IPR000649=Initiation factor 2B-related CG10315 16-Dec-15 2015_12 ENSDARG00000014004(eif2b4) YGR083C(GCD2) WBGene00008670(F11A3.2) ENSXETG00000020959(EIF2B4) ENSMUSG00000029145(Eif2b4) ENSG00000115211(EIF2B4) "lethal - all die before end of pupal stage,some die during pupal stage,lethal,neuroanatomy defective,visible,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum" FBgn0052524 CG32524 http://flybase.net/reports/FBgn0052524.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001399 l(1)2Fb lethal (1) 2Fb http://flybase.net/reports/FBgn0001399.html gene "N4, N9, JC155, VA172, l(1)N9, l68, l(1)N6" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0031592 Art2 Arginine methyltransferase 2 http://flybase.net/reports/FBgn0031592.html protein_coding_gene 0016274=protein-arginine N-methyltransferase activity 0018216=peptidyl-arginine methylation 0005634=nucleus "DART2, CG3675" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025799=Protein arginine N-methyltransferase" CG3675 16-Dec-15 2015_12 viable FBgn0042178 CG32165 http://flybase.net/reports/FBgn0042178.html "FBgn0014929, FBgn0036645" protein_coding_gene 0008536=Ran GTPase binding 0006886=intracellular protein transport "anon-73Bb, Imp4/5, CG18861, CG18218, unnamed" "IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG32165 16-Dec-15 2015_12 ENSXETG00000014621(IPO4) ENSMUSG00000002319(Ipo4) ENSG00000196497(IPO4) "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0001610 l(1)dd2 lethal (1) discs degenerate 2 http://flybase.net/reports/FBgn0001610.html gene "l(1)d.deg.2, l(1)d.deg.-2, l(1)d.degII" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" imaginal disc FBgn0032008 CG14277 http://flybase.net/reports/FBgn0032008.html protein_coding_gene CG14277 16-Dec-15 2015_12 FBgn0027297 l(1)G0143 lethal (1) G0143 http://flybase.net/reports/FBgn0027297.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" third instar larva FBgn0053108 CG33108 http://flybase.net/reports/FBgn0053108.html "FBgn0039138, FBgn0047137" protein_coding_gene "C19orf54Nt, CG5926, BcDNA:RE26840" CG33108 16-Dec-15 2015_12 ENSDARG00000039513(zgc:153119) WBGene00010610(K07A1.3) ENSMUSG00000078786 ENSG00000188493(C19orf54) "viable,fertile,body color defective" mesothoracic tergum FBgn0267743 CR46074 http://flybase.net/reports/FBgn0267743.html non_protein_coding_gene CR46074 16-Dec-15 2015_12 FBgn0025390 Mur2B Mucin related 2B http://flybase.net/reports/FBgn0025390.html FBgn0025389 protein_coding_gene "0008061=chitin binding, 0005201=extracellular matrix structural constituent" 0006030=chitin metabolic process "0031012=extracellular matrix, 0042600=chorion, 0005576=extracellular region" "EG:56G7.1, CG14796, Mur2B" IPR002557=Chitin binding domain CG14796 16-Dec-15 2015_12 FBgn0260352 GSd428 http://flybase.net/reports/FBgn0260352.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0084017 CR41454 http://flybase.net/reports/FBgn0084017.html FBan0041454 pseudogene_attribute CG41454 CR41454 16-Dec-15 2015_12 FBgn0037322 Or83a Odorant receptor 83a http://flybase.net/reports/FBgn0037322.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell 0032590=dendrite membrane "CG10612, 83A.1, DOR44, 83a" "IPR004117=Olfactory receptor, Drosophila" CG10612 16-Dec-15 2015_12 viable FBgn0032694 MESR3 Misexpression suppressor of ras 3 http://flybase.net/reports/FBgn0032694.html protein_coding_gene 0046580=negative regulation of Ras protein signal transduction "CG15162, mis-expression suppressor of ras 3" IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) CG15162 16-Dec-15 2015_12 viable FBgn0036537 CG18081 http://flybase.net/reports/FBgn0036537.html FBgn0047075 protein_coding_gene BcDNA:RE63284 "IPR015880=Zinc finger, C2H2-like, IPR007513=Uncharacterised protein family SERF, IPR026939=At2g23090-like" CG18081 16-Dec-15 2015_12 "ENSDARG00000056307(zgc:92624),ENSDARG00000035678(zgc:91910)" "WBGene00019609(K10B3.1),WBGene00007223(C01F6.9)" "ENSXETG00000006633(),ENSXETG00000027722(TNeu080o10.1)" "ENSMUSG00000062397(Zfp706),ENSMUSG00000067015(Gm10193)" ENSG00000120963(ZNF706) FBgn0266907 CR45367 http://flybase.net/reports/FBgn0266907.html non_protein_coding_gene CR45367 16-Dec-15 2015_12 FBgn0065888 l(2)SH0225 lethal (2) SH0225 http://flybase.net/reports/FBgn0065888.html gene l(2)SH2 0225 16-Dec-15 2015_12 "lethal,recessive" FBgn0263521 mir-4969 mir-4969 stem loop http://flybase.net/reports/FBgn0263521.html miRNA_gene "dme-mir-4969, miR-4969, CR43506" CR43506 16-Dec-15 2015_12 viable FBgn0265663 CR44470 http://flybase.net/reports/FBgn0265663.html non_protein_coding_gene lincRNA.938 CR44470 16-Dec-15 2015_12 FBgn0265188 CG44253 http://flybase.net/reports/FBgn0265188.html FBgn0050194 protein_coding_gene CG30194 CG44253 16-Dec-15 2015_12 FBgn0032329 Art8 Arginine methyltransferase 8 http://flybase.net/reports/FBgn0032329.html protein_coding_gene "0070611=histone methyltransferase activity (H3-R2 specific), 0016274=protein-arginine N-methyltransferase activity" 0034970=histone H3-R2 methylation 0005634=nucleus "dART8, DART7, CG16840, DART8" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025799=Protein arginine N-methyltransferase" CG16840 16-Dec-15 2015_12 viable FBgn0000804 fs(1)de15 female sterile (1) defective eggs 15 http://flybase.net/reports/FBgn0000804.html gene de15 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion,endochorion" FBgn0022705 Ca-2 Carbonic anhydrase-2 http://flybase.net/reports/FBgn0022705.html gene CA-2 16-Dec-15 2015_12 FBgn0019882 anon-69Aa anon-69Aa http://flybase.net/reports/FBgn0019882.html gene 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0044120 E(rst)B80 E(rst)B80 http://flybase.net/reports/FBgn0044120.html gene 0001745=compound eye morphogenesis B80 16-Dec-15 2015_12 viable FBgn0260610 2L3011 http://flybase.net/reports/FBgn0260610.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0000828 fs(1)A147 female sterile (1) A147 http://flybase.net/reports/FBgn0000828.html gene 0048477=oogenesis "fs(1)M5, fs(1)147" 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0020850 idr indora http://flybase.net/reports/FBgn0020850.html gene 0007292=female gamete generation #098 16-Dec-15 2015_12 female sterile ovary FBgn0003464 sol small optic lobes http://flybase.net/reports/FBgn0003464.html FBgn0031175 protein_coding_gene "0008270=zinc ion binding, 0004198=calcium-dependent cysteine-type endopeptidase activity" "0007399=nervous system development, 0006508=proteolysis, 0007632=visual behavior" "0005737=cytoplasm, 0005622=intracellular" "small optic lobe, CalpD, Sol, SOL, DmSol, nofE, w5000, CG1391, PC79" "IPR001876=Zinc finger, RanBP2-type, IPR001300=Peptidase C2, calpain, catalytic domain, IPR000169=Cysteine peptidase, cysteine active site, IPR022684=Peptidase C2, calpain family" CG1391 16-Dec-15 2015_12 ENSDARG00000060600(LOC100330198) "WBGene00011705(T11A5.6),WBGene00021041(W05G11.4)" ENSXETG00000010331(SOLH) ENSMUSG00000037326(Solh) ENSG00000103326(SOLH) "flight defective,behavior defective,wild-type,viable,neuroanatomy defective,recessive,visual behavior defective" "optic lobe,cell body rind of medulla,Pdf neuron,medulla neuropil,cell body rind of lobula plate,lobula,embryonic/larval optic stalk,lobula plate,central nervous system,adult central nervous system" DRSC20587 I 0.292935429 2.057455565 0.450934372 -0.444434464 -0.716599211 -0.669287331 FBgn0013701 mt:tRNA:N mitochondrial asparagine tRNA http://flybase.net/reports/FBgn0013701.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006304, tRNA[Asn], CR34079" CR34079 16-Dec-15 2015_12 FBgn0085482 CG34453 http://flybase.net/reports/FBgn0085482.html "FBgn0082880, FBgn0054018" protein_coding_gene "CG34018, BP1026" CG34453 16-Dec-15 2015_12 FBgn0002592 E(spl)m2-BFM "Enhancer of split m2, Bearded family member" http://flybase.net/reports/FBgn0002592.html protein_coding_gene "0007219=Notch signaling pathway, 0001708=cell fate specification, 0007423=sensory organ development" "m2, DmelCG6104, E(spl), E(spl) region transcript m2, CG6104, HLHm2, E(Spl)m2, E(spl)m2" CG6104 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 10,11 , embryonic stage | 14-20 hr " " eye disc

, ventral neurogenic region

, mesoderm | presumptive

, morphogenetic furrow | posterior to

, dorsal mesothoracic disc | restricted

, morphogenetic furrow | vicinity of

, proneural cluster &&of dorsal mesothoracic disc

, proneural cluster

" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "sensory mother cell,wing vein L5,anterior dorsocentral bristle,posterior dorsocentral bristle,macrochaeta & adult head-537.4,macrochaeta & mesothoracic tergum-537.4,microchaeta" FBgn0025755 l(3)93DFg lethal (3) 93DFg http://flybase.net/reports/FBgn0025755.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0039764 CG15535 http://flybase.net/reports/FBgn0039764.html protein_coding_gene IPR013730=Fyv7/TAP26 CG15535 16-Dec-15 2015_12 viable FBgn0020335 anon-66BCa anon-66BCa http://flybase.net/reports/FBgn0020335.html gene "unnamed, 7F10" 16-Dec-15 2015_12 FBgn0267247 CR45687 http://flybase.net/reports/FBgn0267247.html non_protein_coding_gene CR45687 16-Dec-15 2015_12 FBgn0022072 l(2)k07803 lethal (2) k07803 http://flybase.net/reports/FBgn0022072.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053125 CG33125 http://flybase.net/reports/FBgn0053125.html protein_coding_gene CG33125 16-Dec-15 2015_12 viable FBgn0026312 Y56 Y56 http://flybase.net/reports/FBgn0026312.html gene 0003729=mRNA binding 0017148=negative regulation of translation 16-Dec-15 2015_12 FBgn0038003 CG3916 http://flybase.net/reports/FBgn0038003.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP154 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG3916 16-Dec-15 2015_12 viable FBgn0035553 CG13722 http://flybase.net/reports/FBgn0035553.html protein_coding_gene CG13722 16-Dec-15 2015_12 viable DRSC24663 K -0.053723364 0.108946896 0.488694115 0.704372612 2.26357354 -0.539041499 FBgn0066069 Su(var)2-7 Su(var)2-7 http://flybase.net/reports/FBgn0066069.html gene 16-Dec-15 2015_12 FBgn0265540 CR44390 http://flybase.net/reports/FBgn0265540.html non_protein_coding_gene CR44390 16-Dec-15 2015_12 FBgn0041252 Femcoat Femcoat http://flybase.net/reports/FBgn0041252.html FBgn0029698 protein_coding_gene 0005213=structural constituent of chorion 0007306=eggshell chorion assembly 0005737=cytoplasm "CG15573, FEMCOAT, femcoat" CG15573 16-Dec-15 2015_12 viable "endochorion,exochorion" FBgn0022626 Dia6 Diaphorase 6 http://flybase.net/reports/FBgn0022626.html gene DIA-6 16-Dec-15 2015_12 FBgn0016936 smi79E smell impaired 79E http://flybase.net/reports/FBgn0016936.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0266785 CR45250 http://flybase.net/reports/FBgn0266785.html non_protein_coding_gene CR45250 16-Dec-15 2015_12 FBgn0267874 CR46162 http://flybase.net/reports/FBgn0267874.html pseudogene_attribute CG12717-related CR46162 16-Dec-15 2015_12 FBgn0036924 hale hale-bopp http://flybase.net/reports/FBgn0036924.html protein_coding_gene CG7570 CG7570 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0259634 B1508 http://flybase.net/reports/FBgn0259634.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,antennal segment,arista" FBgn0266237 CR44932 http://flybase.net/reports/FBgn0266237.html non_protein_coding_gene lincRNA.700 CR44932 16-Dec-15 2015_12 FBgn0050399 CR30399 http://flybase.net/reports/FBgn0050399.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0037109 MED1 Mediator complex subunit 1 http://flybase.net/reports/FBgn0037109.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex" "Mediator, Med1/SOP3/TRAP220, Trap220, CG7162, dTRAP220, FBgn0037109, Med1" "IPR019680=Mediator complex, subunit Med1" CG7162 16-Dec-15 2015_12 ENSXETG00000023696(MED1) ENSMUSG00000018160(Med1) ENSG00000125686(MED1) "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0038223 Afti Aftiphilin http://flybase.net/reports/FBgn0038223.html protein_coding_gene "0008565=protein transporter activity, 0035650=AP-1 adaptor complex binding" "0042051=compound eye photoreceptor development, 0048749=compound eye development, 0046907=intracellular transport" 0032588=trans-Golgi network membrane "CG8538, dAftiphilin, dAfti" "IPR029205=Aftiphilin, clathrin-binding box" CG8538 16-Dec-15 2015_12 ENSMUSG00000049659(Aftph) ENSG00000119844(AFTPH) "size defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,visible,partially lethal - majority die" "eye,ommatidium,trichogen cell,mesothoracic tergum" FBgn0069913 CG4681 http://flybase.net/reports/FBgn0069913.html "FBgn0035029, FBgn0044603" protein_coding_gene anon-WO0140519.29 CG4681 16-Dec-15 2015_12 ENSDARG00000010586(LOC553441) ENSXETG00000024543(TEX9) ENSMUSG00000032219(Tex9) ENSG00000151575(TEX9) "partially lethal - majority die,some die during pupal stage" FBgn0010197 Gyc32E Guanyl cyclase at 32E http://flybase.net/reports/FBgn0010197.html FBgn0053114 protein_coding_gene "0004872=receptor activity, 0004383=guanylate cyclase activity, 0005524=ATP binding, 0004672=protein kinase activity" "0019934=cGMP-mediated signaling, 0006182=cGMP biosynthetic process, 0007165=signal transduction, 0009190=cyclic nucleotide biosynthetic process, 0006468=protein phosphorylation" "0005887=integral component of plasma membrane, 0005886=plasma membrane" "GYC 32E, DMRGC, GC, CG6275, Guanylate cyclase receptor-type, Cyg1, Gyc-r, unnamed, CG33114" "IPR028082=Periplasmic binding protein-like I, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001828=Receptor, ligand binding region, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011009=Protein kinase-like domain" CG33114 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage , embryonic stage | early , larval stage , adult stage && oogenesis stage | stage S10 " " germarium

, adult head

, head

ubiquitous , nurse cell

" FBgn0019658 sAB1 sAB1 http://flybase.net/reports/FBgn0019658.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0027597 CG17712 http://flybase.net/reports/FBgn0027597.html protein_coding_gene 0016491=oxidoreductase activity BcDNA:GH03377 "IPR016040=NAD(P)-binding domain, IPR000683=Oxidoreductase, N-terminal" CG17712 16-Dec-15 2015_12 "ENSDARG00000061363(LOC556899),ENSDARG00000061145(zgc:153587)" "ENSXETG00000025401(gfod1),ENSXETG00000015621(Q5BKK6_XENTR)" "ENSMUSG00000051335(Gfod1),ENSMUSG00000013150(Gfod2)" "ENSG00000141098(GFOD2),ENSG00000145990(GFOD1)" "viable,fertile,visible" trichogen cell FBgn0050241 tRNA:CR30241 transfer RNA:CR30241 http://flybase.net/reports/FBgn0050241.html FBgn0060168 tRNA_gene 0033417=CUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna74-LeuAAG, AE002787.trna15-LeuAAG, CR30241, tRNA:L:AAG:AE002787-b" CR30241 16-Dec-15 2015_12 FBgn0267605 CR45943 http://flybase.net/reports/FBgn0267605.html non_protein_coding_gene CR45943 16-Dec-15 2015_12 FBgn0037445 CG9727 http://flybase.net/reports/FBgn0037445.html protein_coding_gene 0003677=DNA binding "0006355=regulation of transcription, DNA-templated" "IPR003150=DNA-binding RFX-type winged-helix domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG9727 16-Dec-15 2015_12 ENSXETG00000024544(RFX7) ENSMUSG00000037674(Rfx7) ENSG00000181827(RFX7) lethal FBgn0034268 CG4989 http://flybase.net/reports/FBgn0034268.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034546 CG13442 http://flybase.net/reports/FBgn0034546.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0000209=protein polyubiquitination "0005768=endosome, 0005764=lysosome" "IPR011016=Zinc finger, RING-CH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG13442 16-Dec-15 2015_12 "ENSDARG00000062489(zgc:171495),ENSDARG00000037487" "ENSXETG00000017063(MARCH1),ENSXETG00000026961(march8)" viable FBgn0037386 CG1208 http://flybase.net/reports/FBgn0037386.html protein_coding_gene 0005355=glucose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR003663=Sugar/inositol transporter, IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site" CG1208 16-Dec-15 2015_12 "YBR241C(),YGL104C(VPS73)" FBgn0022060 l(2)k08046 lethal (2) k08046 http://flybase.net/reports/FBgn0022060.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027556 CG4928 http://flybase.net/reports/FBgn0027556.html protein_coding_gene 0005886=plasma membrane BcDNA:GH10120 "IPR010291=Ion channel regulatory protein, UNC-93, IPR020846=Major facilitator superfamily domain" CG4928 16-Dec-15 2015_12 ENSDARG00000041554(si:dkey-14a7.1) WBGene00006822(unc-93) ENSXETG00000023303(UNC93A) "ENSMUSG00000067049(Unc93a),ENSMUSG00000056133(Gm9992)" ENSG00000112494(UNC93A) "viable,fertile,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0036686 CG7728 http://flybase.net/reports/FBgn0036686.html protein_coding_gene "0022008=neurogenesis, 0042254=ribosome biogenesis, 0009267=cellular response to starvation" 0005634=nucleus "IPR012948=AARP2CN, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007034=Ribosome biogenesis protein BMS1/TSR1, C-terminal, IPR030387=Bms1/Tsr1-type G domain" CG7728 16-Dec-15 2015_12 YPL217C(BMS1) WBGene00022021(Y61A9LA.10) ENSMUSG00000030138(Bms1) ENSG00000165733(BMS1) "lethal,neuroanatomy defective,partially lethal - majority die,visible,female semi-sterile,female sterile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0027954 lim legs incomplete and malformed http://flybase.net/reports/FBgn0027954.html gene 16-Dec-15 2015_12 FBgn0260355 GSd229 http://flybase.net/reports/FBgn0260355.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0062602 Mod(var)1447 Mod(var)1447 http://flybase.net/reports/FBgn0062602.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1447 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0262102 CG42855 http://flybase.net/reports/FBgn0262102.html protein_coding_gene CG42855 16-Dec-15 2015_12 FBgn0034618 CG9485 http://flybase.net/reports/FBgn0034618.html FBgn0046286 protein_coding_gene "0004135=amylo-alpha-1,6-glucosidase activity, 0004134=4-alpha-glucanotransferase activity" "0005980=glycogen catabolic process, 0005978=glycogen biosynthetic process" "0005634=nucleus, 0005737=cytoplasm" "BEST:GH22856, FBgn0034618" "IPR013781=Glycoside hydrolase, catalytic domain, IPR006421=Glycogen debranching enzyme, metazoa, IPR029436=Eukaryotic glycogen debranching enzyme, N-terminal domain, IPR008928=Six-hairpin glycosidase-like, IPR017853=Glycoside hydrolase superfamily, IPR010401=Glycogen debranching enzyme" CG9485 16-Dec-15 2015_12 ENSDARG00000012709 YPR184W(GDB1) WBGene00011050(agl-1) ENSMUSG00000033400(Agl) ENSG00000162688(AGL) viable FBgn0012033 65F 65F http://flybase.net/reports/FBgn0012033.html gene 16-Dec-15 2015_12 FBgn0262483 Rbp RIM-binding protein http://flybase.net/reports/FBgn0262483.html "FBgn0051302, FBgn0038335, FBgn0038336, FBgn0038333" protein_coding_gene "0007274=neuromuscular synaptic transmission, 0048789=cytoskeletal matrix organization at active zone" 0048788=presynaptic cytoskeletal matrix assembled at active zones "CG43073, drbp, Rab3-interacting molecule (RIM)-binding protein, CG14867, CG5152, CG31302, DRBP, CG5143" "IPR003961=Fibronectin type III, IPR001452=SH3 domain, IPR013783=Immunoglobulin-like fold, IPR011511=Variant SH3 domain" CG43073 16-Dec-15 2015_12 "ENSDARG00000056675,ENSDARG00000001154" WBGene00006513(tag-168) "ENSMUSG00000029420(Rimbp2),ENSMUSG00000034156(Bzrap1)" "ENSG00000060709(RIMBP2),ENSG00000005379(BZRAP1)" DRSC15724 IEK -3.787669555 -2.580382595 -1.649570194 -6.079083919 -1.392361671 2.231061613 FBgn0065880 l(2)SH0237 lethal (2) SH0237 http://flybase.net/reports/FBgn0065880.html gene l(2)SH2 0237 16-Dec-15 2015_12 "lethal,recessive" FBgn0033690 EndoG Endonuclease G http://flybase.net/reports/FBgn0033690.html protein_coding_gene "0046872=metal ion binding, 0004521=endoribonuclease activity, 0004520=endodeoxyribonuclease activity, 0003676=nucleic acid binding" "0007286=spermatid development, 0000001=mitochondrion inheritance, 0035234=ectopic germ cell programmed cell death, 0006261=DNA-dependent DNA replication" "0005739=mitochondrion, 0005743=mitochondrial inner membrane" "dEndoG, endoG, CG8862, endonuclease G" "IPR018524=DNA/RNA non-specific endonuclease, active site, IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG8862 16-Dec-15 2015_12 ENSDARG00000058865(zgc:110020) YJL208C(NUC1) WBGene00000787(cps-6) ENSXETG00000025614(ENDOG) ENSMUSG00000015337(Endog) ENSG00000167136(ENDOG) "viable,fertile,decreased cell death" "spermatid,mitochondrial nucleoid,male germline cell,mitochondrial nucleoidBSC699)" FBgn0065924 l(2)SH0148 lethal (2) SH0148 http://flybase.net/reports/FBgn0065924.html gene l(2)SH2 0148 16-Dec-15 2015_12 "lethal,recessive" FBgn0086213 wbf-2 http://flybase.net/reports/FBgn0086213.html gene 16-Dec-15 2015_12 FBgn0000921 fs(1)ne8 female sterile (1) no eggs 8 http://flybase.net/reports/FBgn0000921.html gene "ne8, fs(1)ne[8]" 16-Dec-15 2015_12 "female sterile,recessive,female sterile germline-dependent" "endochorion,oocyte,dorsal appendage,chorion" FBgn0267248 CR45688 http://flybase.net/reports/FBgn0267248.html non_protein_coding_gene CR45688 16-Dec-15 2015_12 FBgn0026183 rets retiarius http://flybase.net/reports/FBgn0026183.html gene "ret, unnamed" 16-Dec-15 2015_12 "visible,recessive,viable,reduced,fertile,chemical sensitive" "adult cuticle,wing" FBgn0052793 CG32793 http://flybase.net/reports/FBgn0052793.html "FBgn0014096, FBgn0014097, FBgn0029641, FBgn0042172" protein_coding_gene "EG:100G7.2, anon-3Cb, unnamed, EG:100G7.1, CG3591, CG18089, CG18852, anon-3Ca" CG32793 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,viable,visible" mesothoracic tergum FBgn0005144 l(2)DTS6 lethal (2) DTS6 http://flybase.net/reports/FBgn0005144.html gene DTS-L6 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive" FBgn0044050 Ilp3 Insulin-like peptide 3 http://flybase.net/reports/FBgn0044050.html FBgn0036047 protein_coding_gene "0005179=hormone activity, 0005158=insulin receptor binding" "0060180=female mating behavior, 0045475=locomotor rhythm, 0008286=insulin receptor signaling pathway, 0007623=circadian rhythm, 0030431=sleep" 0005615=extracellular space "Drosophila insulin-like peptide 3, CG14167, Dilp-3, insulin-like peptide, Dilp 3, DILP, DILP3, unnamed, DILP-3, Ilp-3, ilp3, Dilp, dILP-3, Dilp3, insulin-like peptide 3, dILP3, dIlp3, dilp3, dilp, Ilp, dilp-3" "IPR016179=Insulin-like, IPR022352=Insulin family, IPR022353=Insulin, conserved site" CG14167 16-Dec-15 2015_12 " larval stage | second instar-- L | third instar , larval stage | third instar " " larval brain | restricted

, larval brain | restricted

anterior & medial " "large body,viable,mating defective" FBgn0016951 tilH touch insensitive larva H http://flybase.net/reports/FBgn0016951.html gene line 75 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0022395 Hex1 Hexokinase 1 http://flybase.net/reports/FBgn0022395.html gene "HEX-1, Hexokinase, hexokinase, HEX, HK" 16-Dec-15 2015_12 FBgn0035696 Best2 Bestrophin 2 http://flybase.net/reports/FBgn0035696.html protein_coding_gene 0005254=chloride channel activity 0006821=chloride transport "0005777=peroxisome, 0005887=integral component of plasma membrane" "dbest2, CG10173, dBest2" "IPR021134=Bestrophin/UPF0187, IPR000615=Bestrophin" CG10173 16-Dec-15 2015_12 "WBGene00022797(ZK688.2),WBGene00007203(B0564.3),WBGene00011868(T20G5.4),WBGene00007204(B0564.4),WBGene00007808(C29F4.2),WBGene00007404(C07A9.8),WBGene00013921(ZC518.1),WBGene00011258(R13.3)" viable FBgn0046767 CR32489 http://flybase.net/reports/FBgn0046767.html non_protein_coding_gene BcDNA:LD42550 16-Dec-15 2015_12 DRSC22955 IE 0.568399764 -1.508553708 2.006411859 0.155732412 0.170586894 -0.463360798 FBgn0053696 CNMaR CNMamide Receptor http://flybase.net/reports/FBgn0053696.html "FBgn0036026, FBgn0052047" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity" 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "CG16726, CG32047, CG33696, Dm CG33696" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG33696 16-Dec-15 2015_12 viable FBgn0032813 CG10262 http://flybase.net/reports/FBgn0032813.html protein_coding_gene "0030337=DNA polymerase processivity factor activity, 0003677=DNA binding" "0006260=DNA replication, 0006275=regulation of DNA replication" "PCNA2, DmPCNA2" "IPR022648=Proliferating cell nuclear antigen, PCNA, N-terminal, IPR022649=Proliferating cell nuclear antigen, PCNA, C-terminal, IPR022659=Proliferating cell nuclear antigen, PCNA, conserved site, IPR000730=Proliferating cell nuclear antigen, PCNA" CG10262 16-Dec-15 2015_12 YBR088C(POL30) WBGene00003955(pcn-1) "viable,fertile" DRSC02030 E -0.058695132 0.627974275 -1.630962365 0.285509151 -0.451659876 -0.645753217 FBgn0020645 Lcp65Aa Lcp65Aa http://flybase.net/reports/FBgn0020645.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG7287, DCP4, Lcp-a, DmelLCp65Aa, DMLCP65a" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG7287 16-Dec-15 2015_12 viable FBgn0031907 CG5171 http://flybase.net/reports/FBgn0031907.html protein_coding_gene 0004805=trehalose-phosphatase activity 0005992=trehalose biosynthetic process "IPR006379=HAD-superfamily hydrolase, subfamily IIB, IPR003337=Trehalose-phosphatase, IPR023214=HAD-like domain" CG5171 16-Dec-15 2015_12 FBgn0039709 Cad99C Cadherin 99C http://flybase.net/reports/FBgn0039709.html "FBgn0039708, FBgn0051009" protein_coding_gene "0005509=calcium ion binding, 0017022=myosin binding" "0032529=follicle cell microvillus organization, 0044331=cell-cell adhesion mediated by cadherin, 0007155=cell adhesion, 0048100=wing disc anterior/posterior pattern formation, 0002385=mucosal immune response, 2000370=positive regulation of clathrin-mediated endocytosis, 0007224=smoothened signaling pathway, 0019722=calcium-mediated signaling, 0045176=apical protein localization, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation, 0032533=regulation of follicle cell microvillus length, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0007304=chorion-containing eggshell formation, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0035239=tube morphogenesis" "0005887=integral component of plasma membrane, 0031526=brush border membrane, 0005768=endosome, 0005902=microvillus, 0016021=integral component of membrane, 0016324=apical plasma membrane" "CG15511, DCad99C, CA-10, CG7805, CG310034, Cad99C, Cadherin99C, CT35624, CG31009, cad99C, CT4930, Dm Cad99C, Cad99c" "IPR015919=Cadherin-like, IPR002126=Cadherin, IPR020894=Cadherin conserved site" CG31009 16-Dec-15 2015_12 "ENSDARG00000008127(pcdh15b),ENSDARG00000052232(pcdh15a)" WBGene00000397(cdh-5) ENSXETG00000018945(PCDH15) ENSMUSG00000052613 ENSG00000150275(PCDH15) "female semi-fertile,female semi-sterile,viable,female sterile,visible,partially lethal - majority die,some die during pupal stage" "vitelline membrane,follicle cell,somatic clone,microvillus | somatic clone,microvillus & follicle cellFRT.RnorCD2.Act5C,egg,microvillus & follicle cell, with Cad99CëÓcyt.UAS.TAvicGFP-EGFP, FRT.RnorCD2.Act5C,microvillus & follicle cell,microvillus & follicle cell, with Cad99C21-5/Cad99C21-6, FRT.RnorCD2.Act5C,trichogen cell,mesothoracic tergum" FBgn0037708 CG9386 http://flybase.net/reports/FBgn0037708.html protein_coding_gene 0008168=methyltransferase activity "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR011671=tRNA (uracil-O(2)-)-methyltransferase" CG9386 16-Dec-15 2015_12 ENSDARG00000033957(zgc:101657) WBGene00016014(C23G10.7) ENSMUSG00000029097(2310079F23Rik) ENSG00000155275(METTL19) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0002924 ncd non-claret disjunctional http://flybase.net/reports/FBgn0002924.html FBgn0010880 protein_coding_gene "0003777=microtubule motor activity, 0008017=microtubule binding, 0008569=ATP-dependent microtubule motor activity, minus-end-directed, 0005524=ATP binding, 0042803=protein homodimerization activity" "0051298=centrosome duplication, 0001578=microtubule bundle formation, 0000022=mitotic spindle elongation, 0007059=chromosome segregation, 0007051=spindle organization, 0031534=minus-end directed microtubule sliding, 0000212=meiotic spindle organization, 0051028=mRNA transport, 0007100=mitotic centrosome separation, 0051297=centrosome organization, 1901673=regulation of mitotic spindle assembly, 0032837=distributive segregation, 0007052=mitotic spindle organization, 0032888=regulation of mitotic spindle elongation, 0090307=mitotic spindle assembly, 0090306=spindle assembly involved in meiosis, 0007018=microtubule-based movement, 0007056=spindle assembly involved in female meiosis" "0030981=cortical microtubule cytoskeleton, 0072687=meiotic spindle, 0005813=centrosome, 0048471=perinuclear region of cytoplasm, 0005872=minus-end kinesin complex, 0005819=spindle, 0005634=nucleus, 0005871=kinesin complex, 1990498=mitotic spindle microtubule" "DmNCD, non-claret-disjunctional, Ncd, nonclaret disjunctional, DmNcd, l(3)05884, non-claret disjunction, unnamed, Claret nondisjunctional, ca, NCD, CG7831, ndc, cd, kinesin-14, Nonclaret disjunctional, KIF C1, Kinesin-14, Non-Claret Disjunctional, KIFC1, nonclaret disjunction, ca[nd]" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR027640=Kinesin-like protein" CG7831 16-Dec-15 2015_12 ENSDARG00000001558(kifc1) YPR141C(KAR3) "WBGene00002225(klp-15),WBGene00002226(klp-16),WBGene00002227(klp-17)" ENSXETG00000020409(KIFC1) "ENSMUSG00000024301(Kifc1),ENSMUSG00000079553(Gm4137)" "ENSG00000056678,ENSG00000204197" " embryonic stage | early , oogenesis stage " polar body nucleus

"meiotic cell cycle defective,mitotic cell cycle defective,fertile,viable,partially lethal - majority die,recessive,lethal,wild-type,partially,semidominant,lethal - all die before end of embryonic stage,some die during embryonic stage,female" "meiosis II & spindle & egg,meiosis & nuclear chromosome & oocyte,spindle & oocyte,mitotic metaphase & spindle,mitotic anaphase & spindle,spindle,S2 cell-line,cytoplasmic microtubule,spindle | embryonic stage,oocyte,aster | embryonic stage,meiosis & nuclear chromosome,mitosis & nuclear chromosome,meiosis & nuclear chromosome | female,mitotic cell cycle,brain,spindle microtubule,astral microtubule,spindle pole" FBgn0033557 CG12325 http://flybase.net/reports/FBgn0033557.html protein_coding_gene "0022008=neurogenesis, 0009267=cellular response to starvation" "IPR007148=Small-subunit processome, Utp12, IPR019775=WD40 repeat, conserved site, IPR011044=Quinoprotein amine dehydrogenase, beta chain-like, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR027145=Periodic tryptophan protein 2, IPR001680=WD40 repeat" CG12325 16-Dec-15 2015_12 ENSDARG00000037109(pwp2h) YCR057C(PWP2) WBGene00018891(F55F8.3) ENSMUSG00000032834(Pwp2) ENSG00000160220 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0065718 l(2)SH0575 lethal (2) SH0575 http://flybase.net/reports/FBgn0065718.html gene l(2)SH2 0575 16-Dec-15 2015_12 "lethal,recessive" FBgn0002551 lh late hatching http://flybase.net/reports/FBgn0002551.html gene 16-Dec-15 2015_12 visible FBgn0032015 Ostë_ Oligosaccharide transferase ë_ subunit http://flybase.net/reports/FBgn0032015.html protein_coding_gene "0035010=encapsulation of foreign target, 0016477=cell migration" 0012505=endomembrane system "MagT1, CG7830, Magnesium transporter subtype 1, dMagT1, OST" "IPR006844=Magnesium transporter protein 1, IPR021149=Oligosaccharyl transferase complex, subunit OST3/OST6, IPR012336=Thioredoxin-like fold" CG7830 16-Dec-15 2015_12 ENSDARG00000058062(magt1) YOR085W(OST3) WBGene00022793(ZK686.3) "ENSXETG00000000190(TUSC3),ENSXETG00000004498(MAGT1)" "ENSMUSG00000039530(Tusc3),ENSMUSG00000031232(Magt1)" "ENSG00000104723(TUSC3),ENSG00000102158(MAGT1)" "viable,fertile,immune response defective,visible" trichogen cell FBgn0267761 CR46092 http://flybase.net/reports/FBgn0267761.html non_protein_coding_gene CR46092 16-Dec-15 2015_12 FBgn0264628 appaloosa appaloosa http://flybase.net/reports/FBgn0264628.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,macrochaeta,ectopic" FBgn0011189 l(1)296-14 lethal (1) 296-14 http://flybase.net/reports/FBgn0011189.html FBgn0010201 gene 296-14 16-Dec-15 2015_12 "lethal,recessive" FBgn0264475 CR43883 http://flybase.net/reports/FBgn0264475.html non_protein_coding_gene lincRNA.411 CR43883 16-Dec-15 2015_12 FBgn0069102 mus323 mutagen-sensitive 323 http://flybase.net/reports/FBgn0069102.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0043983 Su(rst)E358 Su(rst)E358 http://flybase.net/reports/FBgn0043983.html gene 0001745=compound eye morphogenesis E358 16-Dec-15 2015_12 FBgn0040367 CG11382 http://flybase.net/reports/FBgn0040367.html FBgn0029570 protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis EG:BACR42I17.10 CG11382 16-Dec-15 2015_12 viable FBgn0038532 CG14322 http://flybase.net/reports/FBgn0038532.html protein_coding_gene "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG14322 16-Dec-15 2015_12 ENSMUSG00000027288(Zfp106) "viable,fertile" FBgn0011244 Hsp60B Heat shock protein 60 related http://flybase.net/reports/FBgn0011244.html "FBgn0031274, FBgn0044567" protein_coding_gene "0051082=unfolded protein binding, 0042623=ATPase activity, coupled, 0005524=ATP binding" "0042026=protein refolding, 0009408=response to heat, 0006458='de novo' protein folding, 0007286=spermatid development, 0006457=protein folding, 0006626=protein targeting to mitochondrion" "0005759=mitochondrial matrix, 0005739=mitochondrion" "hsp60B, anon-WO0140519.61, Hsp60b, male sterile(2)21D, 152031_at, Hsp 60 related, CG2830, ms(2)21D, ms(2)06619" "IPR027413=GroEL-like equatorial domain, IPR027410=TCP-1-like chaperonin intermediate domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR027409=GroEL-like apical domain, IPR018370=Chaperonin Cpn60, conserved site, IPR001844=Chaperonin Cpn60" CG2830 16-Dec-15 2015_12 YLR259C(HSP60) "male sterile,recessive,viable" FBgn0261700 CR42736 http://flybase.net/reports/FBgn0261700.html non_protein_coding_gene CG42736 CR42736 16-Dec-15 2015_12 FBgn0263552 mir-4961 mir-4961 stem loop http://flybase.net/reports/FBgn0263552.html miRNA_gene "dme-mir-4961, CR43537" CR43537 16-Dec-15 2015_12 FBgn0264709 CR43978 http://flybase.net/reports/FBgn0264709.html non_protein_coding_gene CR43978 16-Dec-15 2015_12 FBgn0264356 8D2 http://flybase.net/reports/FBgn0264356.html gene 16-Dec-15 2015_12 "visible,somatic clone" "eye,somatic clone,antenna,ectopic" FBgn0039719 CG15515 http://flybase.net/reports/FBgn0039719.html FBgn0047150 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0042302=structural constituent of cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix BcDNA:RE21592 IPR000618=Insect cuticle protein CG15515 16-Dec-15 2015_12 viable FBgn0002976 ob oblique http://flybase.net/reports/FBgn0002976.html gene 16-Dec-15 2015_12 "visible,lethal,partially,recessive" "wing,wing vein" FBgn0028240 l(3)S001717 lethal (3) S001717 http://flybase.net/reports/FBgn0028240.html gene 0017/17 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0001922 l(2)25Cc lethal (2) 25Cc http://flybase.net/reports/FBgn0001922.html gene "l(2)jf17, jf17" 16-Dec-15 2015_12 lethal FBgn0002086 l(2)52Da lethal (2) 52Da http://flybase.net/reports/FBgn0002086.html gene "Group-1, Group1" 16-Dec-15 2015_12 lethal FBgn0042686 Tirant\gag gag http://flybase.net/reports/FBgn0042686.html transposable_element_gene "gag, ORF1" 16-Dec-15 2015_12 FBgn0262984 CG43292 http://flybase.net/reports/FBgn0262984.html protein_coding_gene "lincRNA.463, mlncRNA66A2" CG43292 16-Dec-15 2015_12 FBgn0025625 Sik2 Salt-inducible kinase 2 http://flybase.net/reports/FBgn0025625.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0042594=response to starvation" "EG:22E5.8, Salt-induced kinase 2, SIK, CG4290, SIK2" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG4290 16-Dec-15 2015_12 ENSDARG00000058606(si:ch211-235e18.3) "YPL141C(FRK1),YOR233W(KIN4)" WBGene00003916(par-1) ENSXETG00000003762(SIK3) "ENSMUSG00000037112(Sik2),ENSMUSG00000024042(Sik1)" "ENSG00000170145(SIK2),ENSG00000142178(SIK1)" "stress response defective,viable,long lived,calorie restriction conditional" DRSC18522 K 0.04408985 0.497558746 0.039945376 0.213166089 -1.841019891 -0.224295464 FBgn0265876 CR44665 http://flybase.net/reports/FBgn0265876.html non_protein_coding_gene CR44665 16-Dec-15 2015_12 FBgn0005477 l(1)ts1075 lethal (1) ts1075 http://flybase.net/reports/FBgn0005477.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0051514 CR31514 http://flybase.net/reports/FBgn0051514.html FBgn0064901 non_protein_coding_gene BcDNA:RE21847 CR31514 16-Dec-15 2015_12 FBgn0040122 l(2)23CDf lethal (2) 23CDf http://flybase.net/reports/FBgn0040122.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040670 e(y)2b enhancer of yellow 2b http://flybase.net/reports/FBgn0040670.html protein_coding_gene "0001076=RNA polymerase II transcription factor binding transcription factor activity, 0003713=transcription coactivator activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006406=mRNA export from nucleus" "0005634=nucleus, 0000124=SAGA complex, 0005643=nuclear pore" CG14612 "IPR018783=Transcription factor, enhancer of yellow 2" CG14612 16-Dec-15 2015_12 YBR111W-A(SUS1) FBgn0036437 CG5048 http://flybase.net/reports/FBgn0036437.html FBgn0044632 protein_coding_gene anon-WO0140519.238 "IPR012981=PIH1 family, IPR026697=PIH1 domain-containing protein 3" CG5048 16-Dec-15 2015_12 ENSDARG00000038612(mgc35261l) "ENSMUSG00000026063(4930521A18Rik),ENSMUSG00000042433(E230019M04Rik)" ENSG00000080572(CXorf41) viable FBgn0002056 l(2)38Ab lethal (2) 38Ab http://flybase.net/reports/FBgn0002056.html gene l(2)A113 16-Dec-15 2015_12 lethal FBgn0267751 CR46082 http://flybase.net/reports/FBgn0267751.html non_protein_coding_gene Mgn99934 CR46082 16-Dec-15 2015_12 FBgn0010463 l(2)00572 lethal (2) 00572 http://flybase.net/reports/FBgn0010463.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060498 l(3)S107701 lethal (3) S107701 http://flybase.net/reports/FBgn0060498.html gene 1077/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052365 CG32365 http://flybase.net/reports/FBgn0052365.html "FBgn0035821, FBgn0035822, FBgn0040835" protein_coding_gene "CG13682, CG8294, CG13683" CG32365 16-Dec-15 2015_12 "viable,fertile" FBgn0036228 obst-G obstructor-G http://flybase.net/reports/FBgn0036228.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region CG9781 IPR002557=Chitin binding domain CG9781 16-Dec-15 2015_12 viable FBgn0035906 GstO2 Glutathione S transferase O2 http://flybase.net/reports/FBgn0035906.html FBgn0027692 protein_coding_gene "0004734=pyrimidodiazepine synthase activity, 0016782=transferase activity, transferring sulfur-containing groups, 0045174=glutathione dehydrogenase (ascorbate) activity, 0004364=glutathione transferase activity, 0042803=protein homodimerization activity, 0043295=glutathione binding" "0050829=defense response to Gram-negative bacterium, 0045824=negative regulation of innate immune response, 0006749=glutathione metabolic process" "0005739=mitochondrion, 0005737=cytoplasm" "GSTO2, gsto2, CG6673B, CG6673A, DmGSTO1, CG6673, CG6673-B, CG6673-A, anon-EST:Posey29" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR005442=Glutathione S-transferase, omega-class, IPR012336=Thioredoxin-like fold" CG6673 16-Dec-15 2015_12 "ENSDARG00000022183(zgc:92254),ENSDARG00000033285(zgc:101897)" "WBGene00019636(gsto-3),WBGene00001792(gst-44),WBGene00016204(gsto-1)" "ENSXETG00000026602(TEgg023j21.1),ENSXETG00000026601(BC087558.1),ENSXETG00000016907()" "ENSMUSG00000025068(Gsto1),ENSMUSG00000025069(Gsto2)" "ENSG00000148834(GSTO1),ENSG00000065621(GSTO2)" "viable,fertile,chemical sensitive,short lived" FBgn0043553 Su(roDOM)923 Su(roDOM)923 http://flybase.net/reports/FBgn0043553.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0053288 CG33288 http://flybase.net/reports/FBgn0053288.html protein_coding_gene 0030695=GTPase regulator activity "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG33288 16-Dec-15 2015_12 "ENSDARG00000056617,ENSDARG00000057074(rpgrb)" FBgn0015872 Drip Drip http://flybase.net/reports/FBgn0015872.html FBgn0015156 protein_coding_gene "0015250=water channel activity, 0005372=water transmembrane transporter activity" "0055085=transmembrane transport, 0046662=regulation of oviposition, 0030104=water homeostasis, 0006833=water transport, 0003014=renal system process" 0016021=integral component of membrane "Drosophila integral protein, Drosophila Integral Protein, CG9023, anon-48Aa, aquaporin, drip, transcript group I, I, DRIP" "IPR023271=Aquaporin-like, IPR022357=Major intrinsic protein, conserved site, IPR000425=Major intrinsic protein" CG9023 16-Dec-15 2015_12 "ENSDARG00000010565(aqp4),ENSDARG00000023713(aqp1a.1)" YPR192W(AQY1) "WBGene00000172(aqp-4),WBGene00000174(aqp-6),WBGene00000173(aqp-5)" "ENSXETG00000020388(aqp2),ENSXETG00000024580(AQP5),ENSXETG00000013389(),ENSXETG00000024581(),ENSXETG00000021804(MIP),ENSXETG00000005679(AQP4)" "ENSMUSG00000024411(Aqp4),ENSMUSG00000044217(Aqp5),ENSMUSG00000023013(Aqp2),ENSMUSG00000025389(Mip)" "ENSG00000106125(FAM188B),ENSG00000135517(MIP),ENSG00000167580(AQP2),ENSG00000161798(AQP5),ENSG00000171885(AQP4)" "viable,fertile" FBgn0260290 GSd442 http://flybase.net/reports/FBgn0260290.html gene 16-Dec-15 2015_12 lethal FBgn0250835 CG15394 http://flybase.net/reports/FBgn0250835.html "FBgn0031439, FBgn0066938" protein_coding_gene anon-SAGE:Wang-060 CG15394 16-Dec-15 2015_12 FBgn0060742 l(3)S066508 lethal (3) S066508 http://flybase.net/reports/FBgn0060742.html gene 0665/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0267487 Ptp61F Protein tyrosine phosphatase 61F http://flybase.net/reports/FBgn0267487.html "FBgn0003138, FBgn0035219, FBgn0043788, FBgn0044527, FBgn0062112, FBgn0023399" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0005515=protein binding" "0071456=cellular response to hypoxia, 0050732=negative regulation of peptidyl-tyrosine phosphorylation, 0046426=negative regulation of JAK-STAT cascade, 0048477=oogenesis, 0035335=peptidyl-tyrosine dephosphorylation, 0046580=negative regulation of Ras protein signal transduction, 0007377=germ-band extension, 0007411=axon guidance, 0006470=protein dephosphorylation, 0032880=regulation of protein localization, 0007176=regulation of epidermal growth factor-activated receptor activity, 0043407=negative regulation of MAP kinase activity, 0000278=mitotic cell cycle, 0046627=negative regulation of insulin receptor signaling pathway, 0014067=negative regulation of phosphatidylinositol 3-kinase signaling, 0031647=regulation of protein stability, 0008285=negative regulation of cell proliferation" "0048471=perinuclear region of cytoplasm, 0005634=nucleus, 0005737=cytoplasm" "R-PTP 61F, protein tyrosine phosphatase, anon-WO0118547.297, Cytoplasmic Protein tyrosine phosphatase 62A, Ptp-61F, protein-tyrosine-phosphatase, protein tyrosine phosphatase 61F, PTP1B, dPTP61F, BEST:LP01280, anon-WO0140519.98, DCPTP62A, CPtp62A, PTP61F, dptp61F, CG9181, CG9178, DPTP61F, ptp61F" "IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain, IPR000242=PTP type protein phosphatase, IPR016130=Protein-tyrosine phosphatase, active site" CG9181 16-Dec-15 2015_12 "ENSDARG00000007923(ptpn1),ENSDARG00000035986(ptpn2l),ENSDARG00000016481(ptpn2)" "WBGene00012138(T28F4.3),WBGene00017647(F20H11.4),WBGene00009129(F25H5.7),WBGene00018895(F55F8.7)" "ENSXETG00000019669(PTPN2),ENSXETG00000012288(PTPN1)" "ENSMUSG00000024539(Ptpn2),ENSMUSG00000027540(Ptpn1)" "ENSG00000196396(PTPN1),ENSG00000175354(PTPN2)" " embryonic stage && pupal stage && adult stage , embryonic stage | stage 14 " embryonic central nervous system

DRSC08683 E 0.607831757 -0.262320692 0.414293953 -1.631065905 0.380960353 -0.511673265 FBgn0002631 E(spl)m5-HLH "Enhancer of split m5, helix-loop-helix" http://flybase.net/reports/FBgn0002631.html protein_coding_gene "0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0045892=negative regulation of transcription, DNA-templated, 0007399=nervous system development, 0045165=cell fate commitment, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development" 0005634=nucleus "HLH-m5, CG6096, E(spl)-m5, E(spl)m5, HLHm5, E(spl) transcription unit m5, E(spl) region transcript m5, m5, bHLHb36, E(spl) m5, E(spl)M5" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG6096 16-Dec-15 2015_12 "ENSDARG00000069675(her8.2),ENSDARG00000016363(her8a)" " embryonic stage | stage 7-11 , embryonic stage | 2-6 hr , embryonic stage | stage 11-12 , embryonic stage | stage 11 , embryonic stage | stage 11-14 , embryonic stage | stage 10 , embryonic stage | stage 5 " " ectoderm

, mesoderm

, epidermis | restricted

, stomatogastric nervous system | primordium

, posterior midgut proper primordium

, vitellophage

, optic lobe | primordium

, supraesophageal ganglion

, organism | striped

" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,microchaeta,eo neuron,peripheral nervous system,central nervous system" FBgn0058062 CG40062 http://flybase.net/reports/FBgn0058062.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265739 CR44546 http://flybase.net/reports/FBgn0265739.html non_protein_coding_gene CR44546 16-Dec-15 2015_12 FBgn0085587 CG41266 http://flybase.net/reports/FBgn0085587.html FBan0041266 protein_coding_gene 16-Dec-15 2015_12 FBgn0004131 l(2)43Db lethal (2) 43Db http://flybase.net/reports/FBgn0004131.html gene 43Db 16-Dec-15 2015_12 lethal FBgn0266590 CR45115 http://flybase.net/reports/FBgn0266590.html non_protein_coding_gene CR45115 16-Dec-15 2015_12 FBgn0034474 Obp56g Odorant-binding protein 56g http://flybase.net/reports/FBgn0034474.html protein_coding_gene 0005549=odorant binding "0007606=sensory perception of chemical stimulus, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "56g, DmelObp56g, OBP56g, CG13873" IPR006170=Pheromone/general odorant binding protein CG13873 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0060843 l(3)S049215 lethal (3) S049215 http://flybase.net/reports/FBgn0060843.html gene 0492/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0016909 l(3)X39 lethal (3) X39 http://flybase.net/reports/FBgn0016909.html gene X39 16-Dec-15 2015_12 FBgn0024320 Npc1a Niemann-Pick type C-1a http://flybase.net/reports/FBgn0024320.html protein_coding_gene 0008158=hedgehog receptor activity "0032374=regulation of cholesterol transport, 0045456=ecdysteroid biosynthetic process, 0016125=sterol metabolic process, 0007591=molting cycle, chitin-based cuticle, 0007291=sperm individualization, 0030301=cholesterol transport" "0016021=integral component of membrane, 0005765=lysosomal membrane" "dncp1a, Niemann-Pick Type C-1, npc1a, dNPC1, dnpc1a, CG5722, dmNPC1, NPC1, dNPC1a, NPC1a, DmNPC, Npc1_Dm, npc1, Npc1" "IPR000731=Sterol-sensing domain, IPR003392=Patched, IPR004765=Niemann-Pick C type protein" CG5722 16-Dec-15 2015_12 YPL006W(NCR1) WBGene00003561(ncr-1) ENSXETG00000017177(NPC1) ENSMUSG00000024413(Npc1) ENSG00000141458(NPC1) "neuroanatomy defective,aging defective,lethal,recessive,male sterile,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,eclosion defective,locomotor behavior defective,neurophysiology defective,viable,wild-type" "seminal vesicle,sperm individualization complex, with Npc1aUAS.TAvicGFP-EYFP, 2-286,individualization stage spermatid,rhabdomere | adult stage,adult brain,retina,eye,neuropil,sperm individualization complex, with Npc1aunspecified, 2-286" FBgn0014255 l(2)DB2 lethal (2) DB2 http://flybase.net/reports/FBgn0014255.html gene DB2 16-Dec-15 2015_12 "lethal,recessive" FBgn0024697 dalm2 dalmatian-2 http://flybase.net/reports/FBgn0024697.html gene 0046552=photoreceptor cell fate commitment "dalmatian, dalm" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,photoreceptor cell" FBgn0265931 CR44720 http://flybase.net/reports/FBgn0265931.html non_protein_coding_gene CR44720 16-Dec-15 2015_12 FBgn0265590 CR44417 http://flybase.net/reports/FBgn0265590.html non_protein_coding_gene CR44417 16-Dec-15 2015_12 FBgn0046331 l(2)38ABa lethal (2) 38ABa http://flybase.net/reports/FBgn0046331.html gene lethal in 38A/B 16-Dec-15 2015_12 FBgn0011150 l(1)Q226 lethal (1) Q226 http://flybase.net/reports/FBgn0011150.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0259619 B1517 http://flybase.net/reports/FBgn0259619.html gene 16-Dec-15 2015_12 lethal FBgn0029656 CG10793 http://flybase.net/reports/FBgn0029656.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" "IPR003593=AAA+ ATPase domain, IPR006594=LIS1 homology motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG10793 16-Dec-15 2015_12 ENSDARG00000012275(katnal2) ENSMUSG00000025420(Katnal2) viable FBgn0004100 l(2)60Cb lethal (2) 60Cb http://flybase.net/reports/FBgn0004100.html gene 16-Dec-15 2015_12 FBgn0022326 l(1)A33.3 lethal (1) A33.3 http://flybase.net/reports/FBgn0022326.html gene A33.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0003893 tuh1 tumorous head on 1 http://flybase.net/reports/FBgn0003893.html gene "tuh-1, tumorous head in chromosome 1, tuh, tu-1, tumorous head" 16-Dec-15 2015_12 "visible,maternal effect,recessive,cold sensitive" "macrochaeta,maternal effect,cold sensitive" FBgn0259314 C891 http://flybase.net/reports/FBgn0259314.html gene 16-Dec-15 2015_12 visible wing FBgn0035139 CG13891 http://flybase.net/reports/FBgn0035139.html protein_coding_gene CG13891 16-Dec-15 2015_12 FBgn0004051 Zerknittert Zerknittert http://flybase.net/reports/FBgn0004051.html gene Z 16-Dec-15 2015_12 FBgn0032721 CG10602 http://flybase.net/reports/FBgn0032721.html protein_coding_gene "0003735=structural constituent of ribosome, 0004463=leukotriene-A4 hydrolase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" "0006412=translation, 0006508=proteolysis, 0019370=leukotriene biosynthetic process" 0005840=ribosome "pepCG10602, mRpL13" "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR023564=Ribosomal protein L13 domain, IPR015211=Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal, IPR012777=Leukotriene A4 hydrolase, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR005822=Ribosomal protein L13, IPR016024=Armadillo-type fold" CG10602 16-Dec-15 2015_12 ENSDARG00000006029(lta4h) YNL045W(LAP2) "WBGene00022610(ZC416.6),WBGene00016589(C42C1.11)" ENSXETG00000001890(lta4h) ENSMUSG00000015889(Lta4h) ENSG00000111144(LTA4H) viable FBgn0259964 Sfp33A3 Seminal fluid protein 33A3 http://flybase.net/reports/FBgn0259964.html protein_coding_gene 0004857=enzyme inhibitor activity "0032504=multicellular organism reproduction, 0043086=negative regulation of catalytic activity" 0005615=extracellular space "Seminal fluid protein 33A3, CG42474" IPR002350=Kazal domain CG42474 16-Dec-15 2015_12 "ENSDARG00000071806,ENSDARG00000071808(zgc:158852)" ENSMUSG00000024503(Spink3) ENSG00000128040(SPINK2) FBgn0005711 l(1)TK114 lethal (1) TK114 http://flybase.net/reports/FBgn0005711.html gene l114 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0001699 l(1)ESHS20 lethal (1) ESHS20 http://flybase.net/reports/FBgn0001699.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031301 CG14339 http://flybase.net/reports/FBgn0031301.html protein_coding_gene "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG14339 16-Dec-15 2015_12 viable FBgn0259834 out outsiders http://flybase.net/reports/FBgn0259834.html "FBgn0063400, FBgn0028469" protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity "0007281=germ cell development, 0035234=ectopic germ cell programmed cell death, 0055085=transmembrane transport, 0012501=programmed cell death" 0016021=integral component of membrane "outsider, CG8062, BcDNA:LD28120" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8062 16-Dec-15 2015_12 FBgn0260624 2L1738 http://flybase.net/reports/FBgn0260624.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 viable "dorsal air sac primordium,somatic clone" FBgn0038011 CG4066 http://flybase.net/reports/FBgn0038011.html protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion CG4066 16-Dec-15 2015_12 viable FBgn0260280 GSd435 http://flybase.net/reports/FBgn0260280.html gene 16-Dec-15 2015_12 lethal FBgn0053680 CG33680 http://flybase.net/reports/FBgn0053680.html protein_coding_gene 0042562=hormone binding 0009720=detection of hormone stimulus IPR010562=Haemolymph juvenile hormone binding CG33680 16-Dec-15 2015_12 viable FBgn0020333 anon-66Dd anon-66Dd http://flybase.net/reports/FBgn0020333.html gene 547 16-Dec-15 2015_12 FBgn0262139 trh trachealess http://flybase.net/reports/FBgn0262139.html "FBgn0010944, FBgn0026793, FBgn0082659, FBan0006883, FBgn0003749, FBgn0040689, FBgn0260471" protein_coding_gene "0046982=protein heterodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity" "0007431=salivary gland development, 0006355=regulation of transcription, DNA-templated, 0072175=epithelial tube formation, 0048813=dendrite morphogenesis, 0060173=limb development, 0007443=Malpighian tubule morphogenesis, 0007425=epithelial cell fate determination, open tracheal system, 0007424=open tracheal system development, 0046331=lateral inhibition, 0006357=regulation of transcription from RNA polymerase II promoter, 0007435=salivary gland morphogenesis, 0035277=spiracle morphogenesis, open tracheal system, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG42865, bHLHe13, DMU42699, CG13885, CG6883, Trachealess, HDC07747, BP1081, TRH, 3.1, l(3)10512, trachealess, unnamed, Trh" "IPR001610=PAC motif, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR000014=PAS domain, IPR013655=PAS fold-3, IPR013767=PAS fold" CG42865 16-Dec-15 2015_12 WBGene00001851(hif-1) "ENSMUSG00000001988(Npas1),ENSMUSG00000021010(Npas3)" "ENSG00000130751(NPAS1),ENSG00000151322(NPAS3)" " embryonic stage , embryonic stage | stage >=8 , embryonic stage | stage >=13 , embryonic stage | stage >=11 " " embryonic/larval tracheal system

, embryonic/larval salivary gland

, central nervous system | restricted

, tracheal primordium

, tracheal pit

, salivary gland body primordium

, embryonic salivary gland

, filzkorper

, embryonic/larval trachea

, embryonic/larval salivary gland duct

" " embryonic stage |stage 14 , embryonic stage | stage 11 , embryonic stage | stage 15 , embryonic stage " " embryonic/larval posterior spiracle

, tracheal primordium

, embryonic/larval salivary gland duct

, embryonic/larval tracheal system

" "lethal,recessive,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible" "trachea,filzkorper,embryonic/larval salivary gland duct,embryonic/larval salivary gland,tracheal pit,tracheal branch primordium,abdominal lateral pentascolopidial chordotonal organ lch5 & growth cone,embryonic/larval trachea,embryonic/first instar larval cuticle,embryonic/larval muscle system,embryonic salivary gland duct,embryonic/larval tracheocyte,Malpighian tubule,ureter,embryonic/larval hindgut,tracheal primordium,presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,ectopic,embryonic epidermis,chaeta,supernumerary" FBgn0083239 EP2444 EP2444 http://flybase.net/reports/FBgn0083239.html gene 16-Dec-15 2015_12 FBgn0024684 l(1)HF326 lethal (1) HF326 http://flybase.net/reports/FBgn0024684.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0020334 anon-66Dc anon-66Dc http://flybase.net/reports/FBgn0020334.html gene 507 16-Dec-15 2015_12 FBgn0039809 CG15547 http://flybase.net/reports/FBgn0039809.html protein_coding_gene "0005524=ATP binding, 0004550=nucleoside diphosphate kinase activity" "0006183=GTP biosynthetic process, 0006228=UTP biosynthetic process, 0006165=nucleoside diphosphate phosphorylation, 0006241=CTP biosynthetic process" IPR001564=Nucleoside diphosphate kinase CG15547 16-Dec-15 2015_12 viable FBgn0015385 en::Rnor\GR GR http://flybase.net/reports/FBgn0015385.html engineered_fusion_gene en::GR 16-Dec-15 2015_12 FBgn0015561 unpg unplugged http://flybase.net/reports/FBgn0015561.html FBgn0014101 protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007424=open tracheal system development, 0051960=regulation of nervous system development, 0006355=regulation of transcription, DNA-templated, 0007420=brain development, 0007426=tracheal outgrowth, open tracheal system" 0005634=nucleus "unp, anon-45C, upg, CG1650, Gbx" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR031253=Homeobox protein unplugged" CG1650 16-Dec-15 2015_12 "ENSDARG00000002933(gbx2),ENSDARG00000069020,ENSDARG00000071418(gbx1)" "ENSXETG00000003293(gbx2),ENSXETG00000003290()" "ENSMUSG00000034486(Gbx2),ENSMUSG00000067724(Gbx1)" "ENSG00000168505(GBX2),ENSG00000164900(GBX1)" " embryonic stage | stage 13 , embryonic stage | stage 11 , embryonic stage | stage 8 , embryonic stage | stage 9 , embryonic stage | stage 14 , embryonic stage " " metathoracic tracheal pit

, mesothoracic tracheal pit

, ventral midline

, neuroblast

, ectoderm | lateral prothoracic segment

, embryonic/larval ganglionic branch

, abdominal tracheal pit 1--7

, central nervous system

, ectoderm | lateral labial segment

, cerebral branch

, tracheal system

" " embryonic stage | stage 13 , embryonic stage | stage 11 , embryonic stage | stage 9 , embryonic stage | stage 14 , embryonic stage | stage 8 , embryonic stage " " mesothoracic tracheal pit

, cerebral branch | precursor

, ectoderm | lateral prothoracic segment

, embryonic/larval ganglionic branch

, abdominal tracheal pit 1--7

, ventral midline

, metathoracic tracheal pit

, neuroblast

, central nervous system

, ectoderm | lateral labial segment

, tracheal system

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "cerebral branch,cerebral anastomosis,ganglionic branch 0,ganglionic branch 1,ganglionic branch 2,ganglionic branch 3,ganglionic branch 4,ganglionic branch 5,ganglionic branch 6,ganglionic branch 7,ganglionic branch 8,ganglionic branch 9,wing,trichogen cell,mesothoracic tergum" FBgn0037926 Elp1 Elongator complex protein 1 http://flybase.net/reports/FBgn0037926.html protein_coding_gene 0008607=phosphorylase kinase regulator activity "0009047=dosage compensation by hyperactivation of X chromosome, 0006357=regulation of transcription from RNA polymerase II promoter, 0006952=defense response, 0016246=RNA interference, 0007165=signal transduction" "0005737=cytoplasm, 0008023=transcription elongation factor complex" "elp1, D-elp1, CG10535, ELP1" "IPR006849=IKI3, IPR011042=Six-bladed beta-propeller, TolB-like" CG10535 16-Dec-15 2015_12 ENSDARG00000006495(ikbkapl) YLR384C(IKI3) WBGene00022463(elpc-1) ENSMUSG00000028431(Ikbkap) ENSG00000070061(IKBKAP) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031139 CG11227 http://flybase.net/reports/FBgn0031139.html protein_coding_gene CG11227 16-Dec-15 2015_12 viable FBgn0033405 CG13954 http://flybase.net/reports/FBgn0033405.html protein_coding_gene CG13954 16-Dec-15 2015_12 viable FBgn0053869 His4:CG33869 His4:CG33869 http://flybase.net/reports/FBgn0053869.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33869 "IPR009072=Histone-fold, IPR001951=Histone H4, IPR019809=Histone H4, conserved site" CG33869 16-Dec-15 2015_12 "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) FBgn0259745 wech wech http://flybase.net/reports/FBgn0259745.html protein_coding_gene "0008270=zinc ion binding, 0030674=protein binding, bridging" "0016203=muscle attachment, 0033632=regulation of cell-cell adhesion mediated by integrin" "0005622=intracellular, 0005927=muscle tendon junction" "CG42396, dappled, dpld, Wech, Dpld, CG1624, lin-41, Dappled" "IPR001258=NHL repeat, IPR013017=NHL repeat, subgroup, IPR000315=B-box-type zinc finger, IPR011042=Six-bladed beta-propeller, TolB-like" CG42396 16-Dec-15 2015_12 WBGene00003026(lin-41) ENSXETG00000005362(TRIM71) ENSMUSG00000079259(Trim71) ENSG00000206557(TRIM71) "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,viable" "embryonic/larval somatic muscle,eye,ommatidium,interommatidial bristle,pigment cell,lens" FBgn0265508 CR44370 http://flybase.net/reports/FBgn0265508.html non_protein_coding_gene CR44370 16-Dec-15 2015_12 FBgn0010269 Dsor1 Downstream of raf1 http://flybase.net/reports/FBgn0010269.html protein_coding_gene "0004702=receptor signaling protein serine/threonine kinase activity, 0004708=MAP kinase kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0070374=positive regulation of ERK1 and ERK2 cascade, 0042386=hemocyte differentiation, 0006468=protein phosphorylation, 0007362=terminal region determination, 0046579=positive regulation of Ras protein signal transduction, 0000165=MAPK cascade, 0007095=mitotic G2 DNA damage checkpoint, 0007165=signal transduction, 0007298=border follicle cell migration, 0033314=mitotic DNA replication checkpoint, 0071481=cellular response to X-ray, 0008595=anterior/posterior axis specification, embryo, 0040018=positive regulation of multicellular organism growth" "0005635=nuclear envelope, 0000793=condensed chromosome" "Mek, MAP Kinase Kinase, DRODSOR1, MAPK kinase, DSor1, Dmek, D-Sor, DMEK-1, dSor1, Su(Raf)34B, MEK/Dsor1, sor/MEK1, Dsor, Drosophila MEK, MAPKK, D-MEK, EK1-1, Map kinase kinase, DSORT, D-mek, SOR, MEK1/2, dSor, mitogen-activated protein kinase kinase, mek, D-MEK/Dsor, sor, D-SOR, D-Mek, D-sor, Sor, CG15793, downstream suppressor of Raf 1, dMEK, D-sor-1, MEK, DSOR1, DSor, dsor1" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG15793 16-Dec-15 2015_12 "ENSDARG00000006609(map2k2),ENSDARG00000068918(zgc:172250),ENSDARG00000007825(map2k1)" "YOR231W(MKK1),YPL140C(MKK2)" WBGene00003186(mek-2) ENSXETG00000015887(map2k1) "ENSMUSG00000004936(Map2k1),ENSMUSG00000035027(Map2k2)" "ENSG00000169032(MAP2K1),ENSG00000126934(MAP2K2)" embryonic stage -- adult stage "lethal,recessive,wild-type,polyphasic,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,dominant,some die during immature adult stage,lethal - all die before end of pupal stage,some die during pupal stage" "ommatidium,germarium,spectrosome | supernumeraryunspecified,imaginal disc,somatic clone,dorsal appendage,photoreceptor cell R7,egg chamber,maternal effect,chorion | maternal effect | somatic clone,eye,pigment cell,embryonic dorsal epidermis,intermediate ventral neurectoderm,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,wing vein,male germline cell,cyst progenitor cell,germline stem cell,mesothoracic tergum,adult heart,adult heart muscle" DRSC18462 IEK -1.737304305 -1.207622298 -2.015873569 -1.892313732 -5.420191583 -5.003384291 FBgn0084044 CG41484 http://flybase.net/reports/FBgn0084044.html FBan0041484 protein_coding_gene 16-Dec-15 2015_12 FBgn0250757 CG42235 http://flybase.net/reports/FBgn0250757.html "FBgn0039392, FBgn0039389, FBgn0051090, FBgn0039390, FBgn0039391, FBgn0039393, FBgn0039394" protein_coding_gene "0008523=sodium-dependent multivitamin transmembrane transporter activity, 0008507=sodium:iodide symporter activity" "0051180=vitamin transport, 0055085=transmembrane transport" 0016021=integral component of membrane "CG8934, CG14539, CG8951, Na/iodide symporter-like, dSLC5A10, CG31090, CG8932, CG8966, CG8957" "IPR001734=Sodium/solute symporter, IPR019900=Sodium/solute symporter, subgroup" CG42235 16-Dec-15 2015_12 YHL016C(DUR3) FBgn0038787 CG4360 http://flybase.net/reports/FBgn0038787.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4360 16-Dec-15 2015_12 WBGene00016154(C27A12.2) viable FBgn0040399 E(spl)m8-HLH::E(spl)më«-HLH http://flybase.net/reports/FBgn0040399.html engineered_fusion_gene "E(spl)::HLHmdelta, E(spl)::E(spl)mdelta-HLH" 16-Dec-15 2015_12 FBgn0033628 CG13203 http://flybase.net/reports/FBgn0033628.html FBgn0027739 protein_coding_gene anon-EST:Posey175 CG13203 16-Dec-15 2015_12 viable FBgn0060398 l(3)S132209b lethal (3) S132209b http://flybase.net/reports/FBgn0060398.html gene 1322/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0027243 l(1)G0268 lethal (1) G0268 http://flybase.net/reports/FBgn0027243.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" pupa FBgn0085218 CG34189 http://flybase.net/reports/FBgn0085218.html protein_coding_gene "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG34189 16-Dec-15 2015_12 FBgn0051736 CG31736 http://flybase.net/reports/FBgn0051736.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0053971 Ir62a Ionotropic receptor 62a http://flybase.net/reports/FBgn0053971.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 62a, DmelIR62a, CG12090, IR62a, CG33971" CG33971 16-Dec-15 2015_12 FBgn0267779 CR46110 http://flybase.net/reports/FBgn0267779.html non_protein_coding_gene CR46110 16-Dec-15 2015_12 FBgn0038702 CG3739 http://flybase.net/reports/FBgn0038702.html protein_coding_gene 0008236=serine-type peptidase activity 0006508=proteolysis "IPR029058=Alpha/Beta hydrolase fold, IPR008758=Peptidase S28" CG3739 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0267144 CR45584 http://flybase.net/reports/FBgn0267144.html non_protein_coding_gene CR45584 16-Dec-15 2015_12 FBgn0031725 DIP-ëá Dpr-interacting protein ëá http://flybase.net/reports/FBgn0031725.html protein_coding_gene "CG14010, DIP-eta, CT33567, 14010" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG14010 16-Dec-15 2015_12 "ENSDARG00000013005(zgc:92901),ENSDARG00000022176(zgc:110372),ENSDARG00000018065(ntm),ENSDARG00000021607(negr1)" FBgn0266236 CR44931 http://flybase.net/reports/FBgn0266236.html non_protein_coding_gene lincRNA.699 CR44931 16-Dec-15 2015_12 FBgn0030010 CG10959 http://flybase.net/reports/FBgn0030010.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR022755=Zinc finger, double-stranded RNA binding" CG10959 16-Dec-15 2015_12 "YPR015C(),YPR013C()" "viable,fertile" DRSC17769 E -0.413203017 -0.103136761 1.779604587 0.18891419 0.115442834 0.045705065 FBgn0063927 GS2159 GS2159 http://flybase.net/reports/FBgn0063927.html gene 16-Dec-15 2015_12 long lived FBgn0065858 l(2)SH0287 lethal (2) SH0287 http://flybase.net/reports/FBgn0065858.html gene l(2)SH2 0287 16-Dec-15 2015_12 "lethal,recessive" FBgn0050249 tRNA:CR30249 transfer RNA:CR30249 http://flybase.net/reports/FBgn0050249.html FBgn0060205 tRNA_gene 0033426=CAC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002787.trna21-HisGTG, CR30249, tRNA:H:GTG:AE002787-d, tRNA[His], chr2R.trna80-HisGTG" CR30249 16-Dec-15 2015_12 FBgn0027090 Aats-gln Glutaminyl-tRNA synthetase http://flybase.net/reports/FBgn0027090.html "FBgn0010867, FBgn0027545" protein_coding_gene "0004819=glutamine-tRNA ligase activity, 0005524=ATP binding" "0048813=dendrite morphogenesis, 0006425=glutaminyl-tRNA aminoacylation" "0005875=microtubule associated complex, 0017101=aminoacyl-tRNA synthetase multienzyme complex, 0005737=cytoplasm" "CG10506, Aast-g1n, l(3)05461, GlnRS, glutaminyl-tRNA synthetase, QRS, qars, BcDNA:GH11673" "IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR020056=Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain, IPR011035=Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain, IPR020058=Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain, IPR004514=Glutamine-tRNA synthetase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR007639=Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, IPR007638=Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2, IPR020061=Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain, IPR020059=Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain, IPR000924=Glutamyl/glutaminyl-tRNA synthetase" CG10506 16-Dec-15 2015_12 ENSDARG00000010316(qars) YOR168W(GLN4) WBGene00001336(qars-1) ENSXETG00000009351(QARS) ENSMUSG00000032604(Qars) ENSG00000172053(QARS) embryonic stage

ubiquitous "lethal,recessive,neuroanatomy defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "adult antennal lobe projection neuron,somatic clone" FBgn0051827 CG31827 http://flybase.net/reports/FBgn0051827.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG31827 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" FBgn0025145 ms(3)A2 ms(3)A2 http://flybase.net/reports/FBgn0025145.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0060963 l(3)S032111b lethal (3) S032111b http://flybase.net/reports/FBgn0060963.html gene 0321/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0037755 CG12945 http://flybase.net/reports/FBgn0037755.html protein_coding_gene 0012505=endomembrane system CG12945 16-Dec-15 2015_12 FBgn0030217 CG2124 http://flybase.net/reports/FBgn0030217.html protein_coding_gene 0044822=poly(A) RNA binding 0005739=mitochondrion IPR013584=RAP domain CG2124 16-Dec-15 2015_12 ENSXETG00000027328(FASTKD5) ENSMUSG00000079043(Fastkd5) ENSG00000215251(FASTKD5) viable DRSC18208 K 0.641232138 -0.037572463 -0.295342998 0.371541342 0.193924177 2.055819098 FBgn0033775 Cyp9h1 Cyp9h1 http://flybase.net/reports/FBgn0033775.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "cytochrome P450, 9h1, CG17577" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG17577 16-Dec-15 2015_12 ENSDARG00000045627(cyp3a65) YHR007C(ERG11) "WBGene00008810(cyp-13A12),WBGene00008809(cyp-13A11),WBGene00014254(cyp-13A10),WBGene00011677(cyp-13A1),WBGene00011674(cyp-13A8),WBGene00010606(cyp-13B2),WBGene00008519(cyp-13B1)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "ENSMUSG00000056035(Cyp3a11),ENSMUSG00000075551(Cyp3a41a),ENSMUSG00000075552(Cyp3a41b),ENSMUSG00000054417(Cyp3a44),ENSMUSG00000038656(Cyp3a16),ENSMUSG00000029727(Cyp3a13),ENSMUSG00000029630(Cyp3a25),ENSMUSG00000070419(Cyp3a57),ENSMUSG00000061292(Cyp3a59)" "ENSG00000160868(CYP3A4),ENSG00000160870(CYP3A7),ENSG00000106258(CYP3A5),ENSG00000021461(CYP3A43),ENSG00000059377(TBXAS1)" viable FBgn0005271 l(3)SG91 lethal (3) SG91 http://flybase.net/reports/FBgn0005271.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0015825 T-B9.4 T-B9.4 http://flybase.net/reports/FBgn0015825.html gene 16-Dec-15 2015_12 FBgn0025757 l(3)93DFe lethal (3) 93DFe http://flybase.net/reports/FBgn0025757.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0260490 l(3)8172 http://flybase.net/reports/FBgn0260490.html gene "0048813=dendrite morphogenesis, 0007409=axonogenesis" 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,axon,dendrite" FBgn0017581 Lk6 Lk6 kinase http://flybase.net/reports/FBgn0017581.html "FBgn0037945, FBgn0037946, FBgn0046349" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0051019=mitogen-activated protein kinase binding, 0016301=kinase activity, 0005524=ATP binding" "0007017=microtubule-based process, 0006468=protein phosphorylation, 0046580=negative regulation of Ras protein signal transduction, 0040008=regulation of growth" "0005737=cytoplasm, 0005829=cytosol, 0005813=centrosome, 0005874=microtubule, 0005635=nuclear envelope" "lk6, CG17342, MNK/LK6, MESR8, anon-WO0172774.84, Lk6, LK6, CG6929" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG17342 16-Dec-15 2015_12 YPL153C(RAD53) "ENSMUSG00000028708(Mknk1),ENSMUSG00000020190(Mknk2)" "small body,decreased cell number,lethal,viable,fertile,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,partially,decreased cell size,developmental rate defective,stress response defective,cell growth defective,somatic clone,chemical sensitive,wild-type,visible,partially lethal - majority die,some die during pupal stage,body color defective" "wing,second instar larva,adult,larva,salivary gland,embryonic/larval fat body,egg & microtubule,egg,chaeta,supernumerary,mesothoracic tergum,trichogen cell" FBgn0085804 CR41571 http://flybase.net/reports/FBgn0085804.html FBan0041571 pseudogene_attribute CR41571 16-Dec-15 2015_12 FBgn0039723 CG15522 http://flybase.net/reports/FBgn0039723.html protein_coding_gene CG15522 16-Dec-15 2015_12 viable FBgn0260761 CG42559 http://flybase.net/reports/FBgn0260761.html "FBan0030182, FBgn0050182" protein_coding_gene CG30182 CG42559 16-Dec-15 2015_12 FBgn0262353 CR43051 http://flybase.net/reports/FBgn0262353.html non_protein_coding_gene "GH14785, psnoRNA:bun-a, RE14176, CG43051" CR43051 16-Dec-15 2015_12 FBgn0050335 CG30335 http://flybase.net/reports/FBgn0050335.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001788 l(1)Mb7 lethal (1) Mb7 http://flybase.net/reports/FBgn0001788.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "macrochaeta,eye,arista" FBgn0023039 l(2)46Ed lethal (2) 46Ed http://flybase.net/reports/FBgn0023039.html "FBgn0019717, FBgn0021827" gene "l(2)k16104, l(2)46CFk, unnamed, 14.39, Complementation group L, L" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0024281 Tabp Truncated actin binding protein http://flybase.net/reports/FBgn0024281.html gene "TABP, DTABP" 16-Dec-15 2015_12 FBgn0033093 CG3270 http://flybase.net/reports/FBgn0033093.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR006076=FAD dependent oxidoreductase CG3270 16-Dec-15 2015_12 ENSDARG00000060790 WBGene00010847(M04B2.4) ENSXETG00000000843(FOXRED1) ENSMUSG00000039048(Foxred1) ENSG00000110074(FOXRED1) viable FBgn0032398 CG6766 http://flybase.net/reports/FBgn0032398.html protein_coding_gene 0012505=endomembrane system cg6766 "IPR009011=Mannose-6-phosphate receptor binding domain, IPR012913=Glucosidase II beta subunit-like" CG6766 16-Dec-15 2015_12 ENSDARG00000069042(erlec1) WBGene00013667(Y105E8A.2) ENSXETG00000015197(BC067973.1) ENSMUSG00000020311(Erlec1) ENSG00000068912(ERLEC1) viable FBgn0026197 noe noe http://flybase.net/reports/FBgn0026197.html "FBgn0027686, FBgn0027690, FBgn0027717, FBgn0027750, FBgn0027772, FBgn0052172, FBgn0066008" protein_coding_gene "anon-EST:Posey101, CG32172, anon-EST:Posey243, anon-EST:Posey292, anon-EST:Posey151, anon-EST:Posey35, Noe, anon-WO02059370.51" CG32172 16-Dec-15 2015_12 viable FBgn0041341 Circe\gag gag http://flybase.net/reports/FBgn0041341.html transposable_element_gene ORF1 16-Dec-15 2015_12 FBgn0060402 l(3)S131216 lethal (3) S131216 http://flybase.net/reports/FBgn0060402.html gene 1312/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267811 CR46136 http://flybase.net/reports/FBgn0267811.html non_protein_coding_gene CR46136 16-Dec-15 2015_12 FBgn0266069 CR44822 http://flybase.net/reports/FBgn0266069.html non_protein_coding_gene CR44822 16-Dec-15 2015_12 FBgn0001895 l(2)21Fa lethal (2) 21Fa http://flybase.net/reports/FBgn0001895.html gene "l(2)neh-9, l(2)neh9" 16-Dec-15 2015_12 lethal FBgn0026671 l(1)G0119 lethal (1) G0119 http://flybase.net/reports/FBgn0026671.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085357 CG34328 http://flybase.net/reports/FBgn0085357.html protein_coding_gene CG34328 16-Dec-15 2015_12 FBgn0038760 MED25 Mediator complex subunit 25 http://flybase.net/reports/FBgn0038760.html protein_coding_gene 0001104=RNA polymerase II transcription cofactor activity "0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0002805=regulation of antimicrobial peptide biosynthetic process, 0007399=nervous system development" 0016592=mediator complex "Med25, CG12254, med25, LD07688, dDrip97, Arc92, dARC92" "IPR021394=Mediator complex, subunit Med25, PTOV activation and synapsin 2, IPR021419=Mediator complex, subunit Med25, von Willebrand factor type A" CG12254 16-Dec-15 2015_12 ENSDARG00000038005(med25) ENSXETG00000000296() ENSMUSG00000002968(Med25) ENSG00000104973(MED25) DRSC25776 K 0.961130692 1.903515822 FBgn0267982 CR46249 http://flybase.net/reports/FBgn0267982.html non_protein_coding_gene CR46249 16-Dec-15 2015_12 FBgn0067376 l(2)NC12 lethal (2) NC12 http://flybase.net/reports/FBgn0067376.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266848 wap wings apart http://flybase.net/reports/FBgn0266848.html "FBgn0004000, FBgn0031186, FBgn0047262" protein_coding_gene "0007517=muscle organ development, 0035332=positive regulation of hippo signaling, 0045927=positive regulation of growth" "CG14614, Riq, 16, 19, riquiqui, section 19, 20, 21, Riquiqui, BcDNA:GM08142, wings-apart, section 22, section 16, l(1)A-200, section 21, 15, Q464, riq, 22, section 15, l(1)Q464, l(1)20Ab, section 20, l(1)Q217, Q217, l(1)HM33" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site" CG14614 16-Dec-15 2015_12 ENSDARG00000054355(dcaf7) YPL247C() WBGene00009976(swan-2) ENSXETG00000005311(wdr68) ENSMUSG00000049354(Dcaf7) ENSG00000136485(DCAF7) FBgn0001141 gs grandchildless http://flybase.net/reports/FBgn0001141.html gene 16-Dec-15 2015_12 "viable,female,female fertile,grandchildless,heat sensitive" "germline cell,female,male" FBgn0046685 Wsck Wsck http://flybase.net/reports/FBgn0046685.html "FBgn0046778, FBgn0051127, FBgn0064782" protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004713=protein tyrosine kinase activity" 0006468=protein phosphorylation 0005886=plasma membrane "WSCK, CG31127, BcDNA:LD25626, BcDNA:SD05152" "IPR003961=Fibronectin type III, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR013783=Immunoglobulin-like fold, IPR002889=Carbohydrate-binding WSC, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG31127 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0038473 Ns1 Nucleostemin ortholog (H. sapiens) 1 http://flybase.net/reports/FBgn0038473.html protein_coding_gene "0016887=ATPase activity, 0005525=GTP binding, 0003924=GTPase activity" "0046626=regulation of insulin receptor signaling pathway, 0009267=cellular response to starvation, 0090307=mitotic spindle assembly, 0042254=ribosome biogenesis, 0040014=regulation of multicellular organism growth, 0042273=ribosomal large subunit biogenesis, 0040018=positive regulation of multicellular organism growth" "0005730=nucleolus, 0001652=granular component" "dmNS1, CG3983, ns1, Nucleostemin 1, nucleostemin 1, NS1" "IPR030378=Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006073=GTP binding domain, IPR014813=Guanine nucleotide-binding protein-like 3, N-terminal domain" CG3983 16-Dec-15 2015_12 ENSDARG00000020595(gnl3l) YER006W(NUG1) WBGene00003821(nst-1) ENSXETG00000007700(GNL3L) ENSMUSG00000025266(Gnl3l) ENSG00000130119(GNL3L) "lethal,melanotic mass phenotype,developmental rate defective,partially lethal - majority die,visible,some die during pupal stage" "melanotic mass | larval stage,head,eye,antenna,arista,midgut imaginal island | larval stage,nucleolus | larval stageda.G32,embryonic/larval salivary gland,mesothoracic tergum" FBgn0044007 Su(rst)B52 Su(rst)B52 http://flybase.net/reports/FBgn0044007.html gene 0001745=compound eye morphogenesis B52 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0030492 CG15754 http://flybase.net/reports/FBgn0030492.html protein_coding_gene 0042302=structural constituent of cuticle IPR000618=Insect cuticle protein CG15754 16-Dec-15 2015_12 viable DRSC19719 EK 1.372118596 1.046749353 1.899991001 -0.230325249 1.635068152 -0.480060619 FBgn0043886 l(3)S118602b lethal (3) S118602b http://flybase.net/reports/FBgn0043886.html gene "1186/02, l(3)S118602" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036895 ms(3)76Cc male sterile (3) 76Cc http://flybase.net/reports/FBgn0036895.html protein_coding_gene 0048515=spermatid differentiation CG9392 CG9392 16-Dec-15 2015_12 "male sterile,viable" FBgn0085198 CG34169 http://flybase.net/reports/FBgn0085198.html protein_coding_gene CG34169 16-Dec-15 2015_12 FBgn0011372 l(3)j5A1 lethal (3) j5A1 http://flybase.net/reports/FBgn0011372.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0010665 l(2)10521 lethal (2) 10521 http://flybase.net/reports/FBgn0010665.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036465 Rpn12R Regulatory particle non-ATPase 12-related http://flybase.net/reports/FBgn0036465.html protein_coding_gene "0006508=proteolysis, 0006511=ubiquitin-dependent protein catabolic process" 0005838=proteasome regulatory particle CG11552 IPR006746=26S proteasome non-ATPase regulatory subunit Rpn12 CG11552 16-Dec-15 2015_12 YFR052W(RPN12) WBGene00004468(rpn-12) ENSXETG00000002818(Q6DEV4_XENTR) FBgn0086306 bxPRE bithorax Polycomb Response Element http://flybase.net/reports/FBgn0086306.html regulatory_region "bx, bx PRE, BXD-PRE, Bithoraxoid Polycomb Response Element" 16-Dec-15 2015_12 FBgn0267087 CR45531 http://flybase.net/reports/FBgn0267087.html non_protein_coding_gene CR45531 16-Dec-15 2015_12 FBgn0005368 Vel Velvet http://flybase.net/reports/FBgn0005368.html gene 16-Dec-15 2015_12 eye FBgn0065378 l(2)SH1672 lethal (2) SH1672 http://flybase.net/reports/FBgn0065378.html gene l(2)SH2 1672 16-Dec-15 2015_12 "lethal,recessive" FBgn0011994 tRNA:T:90Cb transfer RNA:thr:90Cb http://flybase.net/reports/FBgn0011994.html "FBgn0003833, FBgn0051590, FBgn0060046" tRNA_gene "0033437=ACU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[[Thr]], AE002708.trna48-ThrAGT, tRNA:T:AGT:AE002708-c, chr3R.trna54-ThrAGT, tRNA:thr:90Cb, CR31590" CR31590 16-Dec-15 2015_12 FBgn0003400 sht short tarsi http://flybase.net/reports/FBgn0003400.html gene 16-Dec-15 2015_12 "viable,poor,visible" "pigment cell,leg,metatarsus,tarsal segment,macrochaeta,wing" FBgn0017358 l(3)L10 lethal (3) L10 http://flybase.net/reports/FBgn0017358.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069413 JJF170 JJF170 http://flybase.net/reports/FBgn0069413.html gene 16-Dec-15 2015_12 stress response defective FBgn0002510 l(3)SG71 lethal (3) SG71 http://flybase.net/reports/FBgn0002510.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0051201 GluRIIE Glutamate receptor IIE http://flybase.net/reports/FBgn0051201.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity, 0004970=ionotropic glutamate receptor activity" "0035249=synaptic transmission, glutamatergic, 0060025=regulation of synaptic activity, 0006811=ion transport, 0007274=neuromuscular synaptic transmission, 0030510=regulation of BMP signaling pathway" "0016021=integral component of membrane, 0097482=muscle cell postsynaptic density, 0008328=ionotropic glutamate receptor complex" "DmelGluRIIE, GluR-IIE, CG31201" "IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region, IPR001508=Ionotropic glutamate receptor, metazoa, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor" CG31201 16-Dec-15 2015_12 "lethal,recessive,paralytic,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage,viable" "neuromuscular junction,trichogen cell,mesothoracic tergum" DRSC13431 K -0.02878254 0.090746339 -0.203729171 -0.481634618 -2.009041546 -1.023059617 FBgn0053926 CG33926 http://flybase.net/reports/FBgn0053926.html protein_coding_gene CG33926 16-Dec-15 2015_12 FBgn0004536 l(4)102ABi lethal (4) 102ABi http://flybase.net/reports/FBgn0004536.html gene "l(4)ABi, l(4)26" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050161 CG30161 http://flybase.net/reports/FBgn0050161.html "FBgn0035045, FBgn0063329" protein_coding_gene 0022008=neurogenesis "CG4856, BcDNA:AT15604" CG30161 16-Dec-15 2015_12 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC22141 I -0.004883722 2.34870364 -0.631503477 0.187409464 -0.411070267 -0.669454045 FBgn0263445 CR43468 http://flybase.net/reports/FBgn0263445.html non_protein_coding_gene CR43468 16-Dec-15 2015_12 FBgn0020834 l(2)Mass Massachusetts http://flybase.net/reports/FBgn0020834.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038449 CG17562 http://flybase.net/reports/FBgn0038449.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "IPR013120=Male sterility, NAD-binding, IPR016040=NAD(P)-binding domain, IPR026055=Fatty acyl-CoA reductase" CG17562 16-Dec-15 2015_12 viable FBgn0067362 l(2)NC47 lethal (2) NC47 http://flybase.net/reports/FBgn0067362.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041148 hypnos-P hypnos-P http://flybase.net/reports/FBgn0041148.html gene 0001666=response to hypoxia "unnamed, dRED" 16-Dec-15 2015_12 FBgn0033949 CG10131 http://flybase.net/reports/FBgn0033949.html protein_coding_gene 0003857=3-hydroxyacyl-CoA dehydrogenase activity "0055114=oxidation-reduction process, 0006631=fatty acid metabolic process" "IPR006108=3-hydroxyacyl-CoA dehydrogenase, C-terminal, IPR016040=NAD(P)-binding domain, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR006180=3-hydroxyacyl-CoA dehydrogenase, conserved site, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR006176=3-hydroxyacyl-CoA dehydrogenase, NAD binding" CG10131 16-Dec-15 2015_12 ENSDARG00000003675(cryl1) WBGene00022130(Y71F9B.9) ENSXETG00000021105(hadhsc) ENSMUSG00000021947(Cryl1) ENSG00000165475(CRYL1) FBgn0025922 l(3)76BDt lethal (3) 76BDt http://flybase.net/reports/FBgn0025922.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027988 l(3)S128711 lethal (3) S128711 http://flybase.net/reports/FBgn0027988.html gene 1287/11 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0065797 l(2)SH0415 lethal (2) SH0415 http://flybase.net/reports/FBgn0065797.html gene l(2)SH2 0415 16-Dec-15 2015_12 "lethal,recessive" FBgn0027165 l(2)KC-A l(2)Karp and Cherbas A http://flybase.net/reports/FBgn0027165.html gene A 16-Dec-15 2015_12 "lethal,recessive" FBgn0023122 anon-10Al anon-10Al http://flybase.net/reports/FBgn0023122.html gene 4 16-Dec-15 2015_12 FBgn0043384 EP566b EP566b http://flybase.net/reports/FBgn0043384.html gene EP0566b 16-Dec-15 2015_12 FBgn0060625 l(3)S087602 lethal (3) S087602 http://flybase.net/reports/FBgn0060625.html gene 0876/02 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262529 CG43083 http://flybase.net/reports/FBgn0262529.html protein_coding_gene CG43083 16-Dec-15 2015_12 FBgn0037812 CG18545 http://flybase.net/reports/FBgn0037812.html "FBtr0082234, FBpp0081712" protein_coding_gene CG18545-PA CG18545 16-Dec-15 2015_12 FBgn0053381 5SrRNA:CR33381 5SrRNA:CR33381 http://flybase.net/reports/FBgn0053381.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33381 CR33381 16-Dec-15 2015_12 FBgn0039116 CG10375 http://flybase.net/reports/FBgn0039116.html protein_coding_gene IPR001623=DnaJ domain CG10375 16-Dec-15 2015_12 WBGene00001048(dnj-30) ENSXETG00000012902(DNAJC8) ENSMUSG00000054405(Dnajc8) ENSG00000126698(DNAJC8) FBgn0034429 CG18607 http://flybase.net/reports/FBgn0034429.html protein_coding_gene IPR016181=Acyl-CoA N-acyltransferase CG18607 16-Dec-15 2015_12 "WBGene00010887(M7.12),WBGene00010884(M7.8),WBGene00011046(R05H10.7),WBGene00020940(W02D7.4),WBGene00020941(W02D7.5),WBGene00011042(R05H10.1)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031634 Ir25a Ionotropic receptor 25a http://flybase.net/reports/FBgn0031634.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0004984=olfactory receptor activity, 0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity, 0015026=coreceptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0006811=ion transport, 0019226=transmission of nerve impulse, 0050907=detection of chemical stimulus involved in sensory perception" "0071683=sensory dendrite, 0016020=membrane, 0016021=integral component of membrane, 0005929=cilium" "CG15627, CT35778, ionotropic receptor 25a, IR25a, DmelIR25a" "IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor, IPR028082=Periplasmic binding protein-like I, IPR001508=Ionotropic glutamate receptor, metazoa" CG15627 16-Dec-15 2015_12 WBGene00001618(glr-7) "viable,fertile,neurophysiology defective" FBgn0037616 CG8136 http://flybase.net/reports/FBgn0037616.html "FBgn0044573, FBgn0044614" protein_coding_gene 0046331=lateral inhibition "anon-WO0140519.254, anon-WO0140519.56" CG8136 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary,wing" FBgn0000414 Dab Disabled http://flybase.net/reports/FBgn0000414.html protein_coding_gene "0005515=protein binding, 0017124=SH3 domain binding, 0042169=SH2 domain binding" "0048488=synaptic vesicle endocytosis, 0008045=motor neuron axon guidance, 0007399=nervous system development, 0045500=sevenless signaling pathway, 0042051=compound eye photoreceptor development, 0072583=clathrin-mediated endocytosis, 0007349=cellularization, 0022008=neurogenesis, 0007391=dorsal closure" "0030424=axon, 0005737=cytoplasm" "CG9695, dab, disabled, cDNA C" "IPR028761=Protein disabled, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006020=PTB/PI domain" CG9695 16-Dec-15 2015_12 WBGene00001116(dyc-1) "ENSMUSG00000022150(Dab2),ENSMUSG00000028519(Dab1)" " embryonic stage | extended germ band , embryonic stage | early " " embryonic central nervous system

,

ubiquitous , mesoderm

" " embryonic stage , embryonic stage | stage 12 " " embryonic central nervous system

, peripheral nervous system

, somatic muscle

, mesoderm

" "locomotor behavior defective,neuroanatomy defective,neurophysiology defective,heat sensitive,viable,fertile,lethal,maternal effect,male sterile,partially lethal - majority die,female sterile" "rhabdomere R7,synapse,bouton,synaptic vesicle,synapseExel6130),synaptic vesicleExel6130),ganglion mother cell,intersegmental nerve branch ISNb of A1-7,maternal effect,segmental nerve branch SNa of A1-7,embryonic leading edge cell,embryo" FBgn0036532 CG13445 http://flybase.net/reports/FBgn0036532.html protein_coding_gene CG13445 16-Dec-15 2015_12 viable DRSC09992 K -0.660821959 -0.82212809 -0.474838254 -1.330480845 1.969374817 1.394102036 FBgn0020518 snoRNA:Me28S-G764 http://flybase.net/reports/FBgn0020518.html snoRNA_gene 0005730=nucleolus "snoRNA:U21, U21, Me28S-G764(U21), SnoRNA U21, CR32907, snoRNA:21" CR32907 16-Dec-15 2015_12 FBgn0036624 RAF2 RING-associated factor 2 http://flybase.net/reports/FBgn0036624.html FBgn0036625 protein_coding_gene 0008270=zinc ion binding 0031519=PcG protein complex "dRAF2, CG4877, dRING-associated factor 2, CG4689" "IPR002893=Zinc finger, MYND-type" CG4877 16-Dec-15 2015_12 viable FBgn0021945 l(2)k10609 lethal (2) k10609 http://flybase.net/reports/FBgn0021945.html gene P996 16-Dec-15 2015_12 "lethal,recessive" FBgn0044337 3S18\ORF ORF http://flybase.net/reports/FBgn0044337.html transposable_element_gene "0004190=aspartic-type endopeptidase activity, 0003676=nucleic acid binding, 0008270=zinc ion binding" "0006508=proteolysis, 0015074=DNA integration" "IPR012337=Ribonuclease H-like domain, IPR001584=Integrase, catalytic core, IPR001969=Aspartic peptidase, active site, IPR005312=Protein of unknown function DUF1759, IPR001878=Zinc finger, CCHC-type, IPR008042=Retrotransposon, Pao, IPR008737=Peptidase aspartic, putative" 16-Dec-15 2015_12 FBgn0265313 CG44286 http://flybase.net/reports/FBgn0265313.html protein_coding_gene CG44286 16-Dec-15 2015_12 FBgn0040208 Kat60 Katanin 60 http://flybase.net/reports/FBgn0040208.html FBgn0037300 protein_coding_gene "0008568=microtubule-severing ATPase activity, 0017022=myosin binding, 0008017=microtubule binding, 0005524=ATP binding" "0031122=cytoplasmic microtubule organization, 0051013=microtubule severing, 0007017=microtubule-based process, 0030336=negative regulation of cell migration, 0022416=chaeta development, 0008582=regulation of synaptic growth at neuromuscular junction, 0035220=wing disc development, 0000070=mitotic sister chromatid segregation, 0016358=dendrite development, 0007019=microtubule depolymerization" "0005694=chromosome, 0031252=cell leading edge, 0005813=centrosome, 0008352=katanin complex, 0005881=cytoplasmic microtubule, 0005938=cell cortex" "katanin-60, kat60, Katanin 60, DmCG10229, katanin60-dm, katanin, Dm-Kat60, CG10229, katanin 60, Katanin, Katanin-60" "IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR015415=Vps4 oligomerisation, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR028596=Katanin p60 subunit A1" CG10229 16-Dec-15 2015_12 "ENSDARG00000002498(katnal1),ENSDARG00000021827(katna1)" YER047C(SAP1) WBGene00003183(mei-1) ENSXETG00000021382(KATNA1) "ENSMUSG00000041298(Katnal1),ENSMUSG00000019794(Katna1)" "ENSG00000102781(KATNAL1),ENSG00000186625(KATNA1)" "lethal,majority die during larval stage,some die during pupal stage,neuroanatomy defective,neurophysiology defective,viable" "NMJ bouton,class IV dendritic arborizing neuron,dendritic tree,microtubule,NMJ bouton | third instar larval stage,microtubuleC57,dendritic treeppk.PG,mushroom body & axon7B,Kenyon cell,mushroom body alpha-lobe,adult mushroom body" DRSC12378 K -0.360806805 0.850827234 -0.007597754 0.448088556 -1.886065802 0.748121361 FBgn0267214 CR45654 http://flybase.net/reports/FBgn0267214.html non_protein_coding_gene CR45654 16-Dec-15 2015_12 FBgn0023104 anon-23Ab anon-23Ab http://flybase.net/reports/FBgn0023104.html gene transcript C 16-Dec-15 2015_12 FBgn0052586 CG32586 http://flybase.net/reports/FBgn0052586.html protein_coding_gene 16-Dec-15 2015_12 DRSC22518 IE 1.688565289 -0.139529859 0.53069159 1.533620258 0.457060593 -0.060836528 FBgn0030054 Caf1-180 "Chromatin assembly factor 1, p180 subunit" http://flybase.net/reports/FBgn0030054.html protein_coding_gene 0042393=histone binding "0035264=multicellular organism growth, 0006334=nucleosome assembly, 0042023=DNA endoreduplication, 0007444=imaginal disc development, 0034728=nucleosome organization, 0010332=response to gamma radiation, 0000724=double-strand break repair via homologous recombination" "0005634=nucleus, 0033186=CAF-1 complex" "CAF1-180, dCAF-1-p180, CAF1p180, CAF-1 p180, Caf1-180, CAF-1 large subunit, dCAF-1-180, NURF, p180, CG12109, CAF1-p180" "IPR029105=Chromatin assembly factor 1 subunit A, C-terminal, IPR022043=Chromatin assembly factor 1 subunit A" CG12109 16-Dec-15 2015_12 ENSDARG00000062152(chaf1a) "lethal,recessive,suppressor of variegation,dominant,visible,increased cell death,size defective,female sterile germline-dependent,germline clone,somatic clone,radiation sensitive,lethal - all die before end of larval stage,some die during larval stage,wild-type,partially lethal - majority die,some die during pupal stage,endomitotic cell cycle defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "eye,wing,fat body,somatic clone,ommatidium,trichogen cell,mesothoracic tergum,imaginal disc,embryonic/larval salivary gland" FBgn0085701 CG41574 http://flybase.net/reports/FBgn0085701.html FBan0041574 protein_coding_gene 16-Dec-15 2015_12 FBgn0035532 CG15014 http://flybase.net/reports/FBgn0035532.html protein_coding_gene 0003723=RNA binding IPR004114=THUMP domain CG15014 16-Dec-15 2015_12 ENSDARG00000045625(zgc:77221) YGL232W(TAN1) WBGene00020953(W02G9.3) ENSXETG00000005539(thumpd1) ENSMUSG00000030942(Thumpd1) ENSG00000066654(THUMPD1) viable FBgn0035554 CG13721 http://flybase.net/reports/FBgn0035554.html protein_coding_gene CG13721 16-Dec-15 2015_12 lethal FBgn0035325 CG13806 http://flybase.net/reports/FBgn0035325.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13806 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0267450 CR45800 http://flybase.net/reports/FBgn0267450.html non_protein_coding_gene Mgn4103 CR45800 16-Dec-15 2015_12 FBgn0085654 CG41493 http://flybase.net/reports/FBgn0085654.html FBan0041493 protein_coding_gene 16-Dec-15 2015_12 FBgn0086398 BG02348 http://flybase.net/reports/FBgn0086398.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0035422 RpL28 Ribosomal protein L28 http://flybase.net/reports/FBgn0035422.html "FBgn0062095, FBgn0063278" protein_coding_gene 0003735=structural constituent of ribosome "0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0006412=translation, 0022008=neurogenesis, 0007052=mitotic spindle organization" 0022625=cytosolic large ribosomal subunit "GH04183p, putativeribosomal L28e protein, anon-WO0118547.321, L28, 60 S ribosomal protein L28, chr3L:3205394..3205484, CG12740, BcDNA:GH04183" "IPR002672=Ribosomal protein L28e, IPR029004=Ribosomal L28e/Mak16" CG12740 16-Dec-15 2015_12 ENSDARG00000005791(rpl28l) WBGene00004442(rpl-28) ENSXETG00000000132(RPL28) "ENSMUSG00000030432(Rpl28),ENSMUSG00000058905(Gm10051)" ENSG00000108107(RPL28) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC08293 IEK -1.886652918 -1.006913507 1.155928268 -3.536290469 -0.839979592 1.535077813 FBgn0267715 CR46048 http://flybase.net/reports/FBgn0267715.html non_protein_coding_gene Mgn95005 CR46048 16-Dec-15 2015_12 FBgn0001247 Ide Insulin degrading metalloproteinase http://flybase.net/reports/FBgn0001247.html protein_coding_gene "0008270=zinc ion binding, 0046872=metal ion binding, 0004222=metalloendopeptidase activity" "0050829=defense response to Gram-negative bacterium, 0090062=regulation of trehalose metabolic process, 0045089=positive regulation of innate immune response, 0045926=negative regulation of growth, 0048638=regulation of developmental growth, 0006508=proteolysis, 0002021=response to dietary excess, 0008340=determination of adult lifespan, 1901143=insulin catabolic process, 0014067=negative regulation of phosphatidylinositol 3-kinase signaling, 0046662=regulation of oviposition" "0005737=cytoplasm, 0005777=peroxisome, 0005886=plasma membrane" "CG5517, dide, dIDE, ide, dIde, Ide, dlde, Insulin degrading enzyme, insulin-degrading enzyme, IDE" "IPR007863=Peptidase M16, C-terminal, IPR001431=Peptidase M16, zinc-binding site, IPR011249=Metalloenzyme, LuxS/M16 peptidase-like, IPR011765=Peptidase M16, N-terminal, IPR011237=Peptidase M16 domain" CG5517 16-Dec-15 2015_12 YLR389C(STE23) "WBGene00018426(F44E7.4),WBGene00015359(C02G6.1),WBGene00013492(Y70C5C.1),WBGene00015360(C02G6.2),WBGene00016185(C28F5.4)" ENSMUSG00000056999(Ide) ENSG00000119912(IDE) "partially lethal - majority die,small body,long lived,female limited,short lived,large body,viable,size defective,decreased cell size,decreased cell number,developmental rate defective,nutrition conditional,fertile" "hemolymph,wing,salivary gland,wing disc,dorsal compartment,posterior compartment" FBgn0003685 tf trefoil http://flybase.net/reports/FBgn0003685.html gene 16-Dec-15 2015_12 body color defective scutellum FBgn0031925 Cyp4d21 Cyp4d21 http://flybase.net/reports/FBgn0031925.html protein_coding_gene "0005506=iron ion binding, 0004497=monooxygenase activity, 0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" "0007618=mating, 0055114=oxidation-reduction process" "0005737=cytoplasm, 0043231=intracellular membrane-bounded organelle, 0016020=membrane" "cyp4d21, CG6730, sex-specific enzyme 1, 4d21, Cytochrome P450, sxe1" "IPR002403=Cytochrome P450, E-class, group IV, IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450" CG6730 16-Dec-15 2015_12 YMR015C(ERG5) "viable,courtship behavior defective,male,mating defective,recessive" FBgn0261568 CG42682 http://flybase.net/reports/FBgn0261568.html protein_coding_gene CG42682 16-Dec-15 2015_12 FBgn0022097 Vha36-1 Vacuolar H+ ATPase 36kD subunit 1 http://flybase.net/reports/FBgn0022097.html "FBgn0034028, FBgn0045927, FBgn0045934, FBgn0045935, FBgn0066035" protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0046961=proton-transporting ATPase activity, rotational mechanism" "0015991=ATP hydrolysis coupled proton transport, 0015992=proton transport" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0033181=plasma membrane proton-transporting V-type ATPase complex, 0005886=plasma membrane" "vha36, VhaD, anon-WO0153538.21, CG8186, anon-WO0153538.20, vha36-1, ATP6V1D, anon-WO02059370.27, Vha36, Vacuolar H-ATPase subunit D, Vacuolar H[+] ATPase subunit 36-1, l(2)k07207, anon-WO0153538.28" "IPR002699=ATPase, V1 complex, subunit D" CG8186 16-Dec-15 2015_12 ENSDARG00000011175(atp6v1d) YEL051W(VMA8) WBGene00010130(vha-14) ENSXETG00000011222(ATP6V1D) ENSMUSG00000021114(Atp6v1d) ENSG00000100554(ATP6V1D) "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" Malpighian tubule FBgn0266060 Su(var)333 http://flybase.net/reports/FBgn0266060.html gene 333 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0266697 CR45187 http://flybase.net/reports/FBgn0266697.html non_protein_coding_gene CR45187 16-Dec-15 2015_12 FBgn0037712 CG16789 http://flybase.net/reports/FBgn0037712.html protein_coding_gene 0005524=ATP binding "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000048=IQ motif, EF-hand binding site" CG16789 16-Dec-15 2015_12 ENSDARG00000069230(zgc:153738) ENSMUSG00000026301(Iqca) "ENSG00000132321(IQCA1),ENSG00000183016" viable FBgn0003019 Ota3 Olfactory trap abnormal 3 http://flybase.net/reports/FBgn0003019.html gene 0007635=chemosensory behavior "Olfactory-trap-abnormal-3, ota3" 16-Dec-15 2015_12 "smell perception defective,dominant,partially" FBgn0259605 B0256 http://flybase.net/reports/FBgn0259605.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing vein L3" FBgn0029733 CG6927 http://flybase.net/reports/FBgn0029733.html protein_coding_gene 0016934=extracellular-glycine-gated chloride channel activity 0006811=ion transport 0016935=glycine-gated chloride channel complex "CT21430, glycine-gated chloride channel-like" "IPR006201=Neurotransmitter-gated ion-channel, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG6927 16-Dec-15 2015_12 lethal FBgn0264601 CR43950 http://flybase.net/reports/FBgn0264601.html non_protein_coding_gene CG43950 CR43950 16-Dec-15 2015_12 FBgn0065492 l(2)SH1230 lethal (2) SH1230 http://flybase.net/reports/FBgn0065492.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023521 CG3587 http://flybase.net/reports/FBgn0023521.html protein_coding_gene EG:39E1.2 "IPR013641=Protein KTI12/L-seryl-tRNA(Sec) kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3587 16-Dec-15 2015_12 ENSDARG00000054301(zgc:153393) YKL110C(KTI12) WBGene00013332(Y57G11C.43) ENSXETG00000024834(KTI12) ENSMUSG00000073775(Kti12) ENSG00000198841(KTI12) "lethal,recessive,viable" FBgn0262300 mir-988 mir-988 stem loop http://flybase.net/reports/FBgn0262300.html miRNA_gene "miR-20071, CR43007, 988, miR988, miR-988" CR43007 16-Dec-15 2015_12 viable FBgn0031652 jet jetlag http://flybase.net/reports/FBgn0031652.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0045475=locomotor rhythm, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0048512=circadian behavior, 0043153=entrainment of circadian clock by photoperiod" 0019005=SCF ubiquitin ligase complex "Jetlag, FBXL15, JETLAG, JET, CG8873" CG8873 16-Dec-15 2015_12 ENSDARG00000005284(zgc:85882) ENSXETG00000014210(fbxl15) ENSMUSG00000025226(Fbxl15) ENSG00000107872(FBXL15) "photoperiod response variant,locomotor rhythm defective,partially lethal - majority die,some die during pupal stage" FBgn0085770 CR40734 http://flybase.net/reports/FBgn0085770.html FBan0040734 rRNA_gene CR40734 16-Dec-15 2015_12 FBgn0033273 Gasz GASZ ortholog http://flybase.net/reports/FBgn0033273.html FBgn0046275 protein_coding_gene "0034587=piRNA metabolic process, 0006298=mismatch repair, 0046331=lateral inhibition" 0005739=mitochondrion "GASZ, gasz, BEST:LD05795, CG2183" "IPR013761=Sterile alpha motif/pointed domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG2183 16-Dec-15 2015_12 ENSDARG00000038557(LOC100329791) ENSXETG00000010323(ANKS3) ENSMUSG00000022515(Anks3) ENSG00000168096(ANKS3) "viable,visible,female sterile" "chaeta,trichogen cell,supernumerary" FBgn0036125 CG6279 http://flybase.net/reports/FBgn0036125.html protein_coding_gene 0016491=oxidoreductase activity "IPR000415=Nitroreductase-like, IPR029479=Nitroreductase" CG6279 16-Dec-15 2015_12 viable FBgn0034060 CG8370 http://flybase.net/reports/FBgn0034060.html protein_coding_gene 0012505=endomembrane system "IPR008962=PapD-like, IPR022113=Transmembrane protein 131-like" CG8370 16-Dec-15 2015_12 ENSDARG00000056259(LOC557719) WBGene00016170(C27F2.8) ENSMUSG00000026116(Tmem131) ENSG00000075568(TMEM131) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0054046 CR34046 http://flybase.net/reports/FBgn0054046.html FBgn0082649 non_protein_coding_gene "unnamed, BP1091, CG34046, HDC16610" CR34046 16-Dec-15 2015_12 FBgn0260803 EP2-1080 http://flybase.net/reports/FBgn0260803.html gene 16-Dec-15 2015_12 FBgn0003505 Srf Surf wings http://flybase.net/reports/FBgn0003505.html gene 16-Dec-15 2015_12 "lethal,recessive,viable,fertile" wing FBgn0011173 l(1)291-11 lethal (1) 291-11 http://flybase.net/reports/FBgn0011173.html FBgn0010199 gene 291-11 16-Dec-15 2015_12 "lethal,recessive" FBgn0029175 Ext2 Ext2 http://flybase.net/reports/FBgn0029175.html "FBgn0027613, FBgn0053038, FBgn0061353, FBtr0087251, FBpp0086389, FBtr0087252, FBpp0086390, FBtr0087253, FBpp0086391" protein_coding_gene "0050508=glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, 0005515=protein binding, 0015020=glucuronosyltransferase activity, 0050509=N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, 0008375=acetylglucosaminyltransferase activity" "0015012=heparan sulfate proteoglycan biosynthetic process, 0030210=heparin biosynthetic process, 0006044=N-acetylglucosamine metabolic process, 0016055=Wnt signaling pathway, 0008101=decapentaplegic signaling pathway, 0030206=chondroitin sulfate biosynthetic process, 0007224=smoothened signaling pathway, 0006024=glycosaminoglycan biosynthetic process, 0015014=heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" "0016021=integral component of membrane, 0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "sotv, DEXT2, DExt2, dExt2, BcDNA:GH02288, sister of tout-velu, CG33038, Sotv, sister-of-tout-velu, CG8433" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR027673=Exostosin-2, IPR015338=Exostosin , C-terminal, IPR004263=Exostosin-like" CG8433 16-Dec-15 2015_12 ENSDARG00000056648(ext2) ENSXETG00000007546(EXT2) ENSMUSG00000027198(Ext2) ENSG00000151348(EXT2) "segment polarity phenotype,germline clone,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing vein L3,somatic clone,wing vein L4,wing margin,wing margin bristle,ectopic,cell non-autonomous,denticle,germline clone,rescuable maternal effect,embryonic/first instar larval cuticle,wing,wing vein,maternal effect,denticle belt,eye,leg,imaginal disc,wing disc" FBgn0050364 hubl hug-bell http://flybase.net/reports/FBgn0050364.html "FBgn0033284, FBgn0044710" protein_coding_gene "CG2149, anon-WO0140519.168, hug-bell, hubl, CG30364" "IPR006611=Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30364 16-Dec-15 2015_12 viable FBgn0039976 CG17920 http://flybase.net/reports/FBgn0039976.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038524 sll slalom http://flybase.net/reports/FBgn0038524.html "FBgn0046348, FBgn0060350, FBgn0061887" protein_coding_gene "0046964=3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity, 0005459=UDP-galactose transmembrane transporter activity" "0055085=transmembrane transport, 0046963=3'-phosphoadenosine 5'-phosphosulfate transport, 0015012=heparan sulfate proteoglycan biosynthetic process, 0007310=oocyte dorsal/ventral axis specification" 0005794=Golgi apparatus "Slalom, Sll, CG7623, 1422/14, anon-WO0172774.85, l(3)S142214, anon-WO0118547.555" IPR013657=UAA transporter CG7623 16-Dec-15 2015_12 ENSDARG00000007886(slc35b2) YPL244C(HUT1) WBGene00004206(pst-1) ENSXETG00000010892(Q6P329_XENTR) ENSMUSG00000037089(Slc35b2) ENSG00000157593(SLC35B2) "viable,lethal,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "wing vein L5,wing,wing vein,ectopic,somatic clone,embryonic/first instar larval cuticle,denticle belt,1st posterior cell,wing vein L2,embryonic ventral epidermis,maternal effect" FBgn0034408 sano serrano http://flybase.net/reports/FBgn0034408.html protein_coding_gene "0035159=regulation of tube length, open tracheal system, 0042067=establishment of ommatidial planar polarity" 0045179=apical cortex CG12758 IPR025946=CABIT domain CG12758 16-Dec-15 2015_12 "planar polarity defective,visible,somatic clone,cell non-autonomous,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,viable" "embryonic/larval dorsal trunk,macrochaeta,wing,wing hair,1st posterior cell,ommatidium,eye photoreceptor cell,somatic clone,embryonic/larval salivary gland,cell non-autonomous" FBgn0037615 CG11760 http://flybase.net/reports/FBgn0037615.html FBgn0063158 protein_coding_gene BcDNA:LD16427 "IPR019184=Uncharacterised protein family, transmembrane-17" CG11760 16-Dec-15 2015_12 ENSXETG00000023963(TMEM216) "ENSMUSG00000024667(Tmem216),ENSMUSG00000025505(Tmem80)" ENSG00000187049(TMEM216) "partially lethal - majority die,some die during pupal stage,viable" FBgn0000388 Curl Curl http://flybase.net/reports/FBgn0000388.html gene "Coi, Coildex, Coiled, Cu, Cd" 16-Dec-15 2015_12 "viable,visible,lethal,recessive,dominant,fertile" wing FBgn0036090 CG8009 http://flybase.net/reports/FBgn0036090.html FBgn0064924 protein_coding_gene "0010867=positive regulation of triglyceride biosynthetic process, 0035307=positive regulation of protein dephosphorylation" "0071595=Nem1-Spo7 phosphatase complex, 0005737=cytoplasm, 0031965=nuclear membrane" BcDNA:LD14173 IPR019168=Nuclear envelope phosphatase-regulatory subunit 1 CG8009 16-Dec-15 2015_12 ENSDARG00000036064(zgc:110674) WBGene00011828(T19A6.3) ENSXETG00000024034(TEgg132c10.1) ENSMUSG00000036810(Tmem188) viable FBgn0264531 l(3)ff30 http://flybase.net/reports/FBgn0264531.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037727 CG8358 http://flybase.net/reports/FBgn0037727.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13" CG8358 16-Dec-15 2015_12 "viable,fertile" FBgn0032143 CG4017 http://flybase.net/reports/FBgn0032143.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR000834=Peptidase M14, carboxypeptidase A, IPR009020=Proteinase inhibitor, propeptide, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide" CG4017 16-Dec-15 2015_12 "WBGene00020281(T06A4.1),WBGene00021213(Y18H1A.9)" "ENSXETG00000016076(CPA3),ENSXETG00000016077(cbp1)" viable FBgn0035218 CG9173 http://flybase.net/reports/FBgn0035218.html protein_coding_gene 0051726=regulation of cell cycle CG9173 16-Dec-15 2015_12 FBgn0050282 CG30282 http://flybase.net/reports/FBgn0050282.html FBgn0047194 protein_coding_gene BcDNA:LD42239 16-Dec-15 2015_12 DRSC22227 K 0.133208971 0.191836971 -0.427759086 0.085412857 -0.198074442 1.509068354 FBgn0028204 l(3)S014308 lethal (3) S014308 http://flybase.net/reports/FBgn0028204.html gene 0143/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0036783 CheA75a Chemosensory protein A 75a http://flybase.net/reports/FBgn0036783.html FBgn0063178 protein_coding_gene 0007606=sensory perception of chemical stimulus 0005576=extracellular region "CG7313, BcDNA:HL02449, CheA75a" IPR010512=Protein of unknown function DUF1091 CG7313 16-Dec-15 2015_12 viable FBgn0084965 2.3.26 2.3.26 http://flybase.net/reports/FBgn0084965.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0003297 rubb rubbish http://flybase.net/reports/FBgn0003297.html gene 0001700=embryonic development via the syncytial blastoderm "rub, rubish" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0069959 CG41058 http://flybase.net/reports/FBgn0069959.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033439 CG1773 http://flybase.net/reports/FBgn0033439.html FBgn0050002 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP74 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG1773 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0259190 Ir7d Ionotropic receptor 7d http://flybase.net/reports/FBgn0259190.html "FBan0015327, FBgn0029967" protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG15327, ionotropic receptor 7d, IR7d, CG42294, DmelIR7d" CG42294 16-Dec-15 2015_12 FBgn0062674 EP2448 EP2448 http://flybase.net/reports/FBgn0062674.html gene EP(2)2448 16-Dec-15 2015_12 FBgn0052369 CG32369 http://flybase.net/reports/FBgn0052369.html "FBgn0035818, FBgn0035819" protein_coding_gene "0008270=zinc ion binding, 0004176=ATP-dependent peptidase activity" 0006508=proteolysis "CG7388, CG13684" "IPR019734=Tetratricopeptide repeat, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR003111=ATP-dependent protease La (LON), substrate-binding domain, IPR017907=Zinc finger, RING-type, conserved site, IPR011990=Tetratricopeptide-like helical domain, IPR015947=PUA-like domain, IPR013026=Tetratricopeptide repeat-containing domain" CG32369 16-Dec-15 2015_12 ENSXETG00000013825(rnf127) "ENSMUSG00000039633(Lonrf1),ENSMUSG00000016239(Lonrf3),ENSMUSG00000048814(Lonrf2)" "ENSG00000170500(LONRF2),ENSG00000175556(LONRF3),ENSG00000154359(LONRF1)" "viable,fertile" DRSC10834 E 0.033188987 -0.536227494 2.209639196 -1.200422576 0.621476889 0.930578903 FBgn0262122 739b http://flybase.net/reports/FBgn0262122.html gene 16-Dec-15 2015_12 FBgn0015578 ë_Tub60D::ë_Tub85D ë_Tub60D::ë_Tub85D http://flybase.net/reports/FBgn0015578.html engineered_fusion_gene beta2beta3 16-Dec-15 2015_12 male sterile axoneme FBgn0259999 CG41072 http://flybase.net/reports/FBgn0259999.html "FBgn0069951, FBgn0046672" protein_coding_gene "38C.23, anon-38C.23" 16-Dec-15 2015_12 FBgn0060307 l(3)S148307 lethal (3) S148307 http://flybase.net/reports/FBgn0060307.html gene 1483/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0263113 CG43370 http://flybase.net/reports/FBgn0263113.html "FBgn0034238, FBgn0034239" protein_coding_gene 0042384=cilium assembly "CG18631, CG18432" "IPR000008=C2 domain, IPR028928=CC2D2A, N-terminal, C2 domain" CG43370 16-Dec-15 2015_12 ENSMUSG00000039765(Cc2d2a) ENSG00000048342(CC2D2A) FBgn0038516 P5cr-2 Pyrroline-5-carboxylate reductase-like 2 http://flybase.net/reports/FBgn0038516.html protein_coding_gene 0004735=pyrroline-5-carboxylate reductase activity "0055114=oxidation-reduction process, 0006561=proline biosynthetic process" "CG5840, CT18319, Pyrroline-5-carboxylate reductase" "IPR029036=Pyrroline-5-carboxylate reductase, dimerisation domain, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR000304=Pyrroline-5-carboxylate reductase, IPR016040=NAD(P)-binding domain, IPR028939=Pyrroline-5-carboxylate reductase, catalytic, N-terminal" CG5840 16-Dec-15 2015_12 "ENSDARG00000053965(pycr1),ENSDARG00000028718" YER023W(PRO3) WBGene00010924(M153.1) ENSXETG00000005381(pycr2) ENSMUSG00000022571(Pycrl) "ENSG00000183010(PYCR1),ENSG00000218497,ENSG00000143811(PYCR2)" viable FBgn0000742 fs(1)A180 female sterile (1) A180 http://flybase.net/reports/FBgn0000742.html gene 0048477=oogenesis fs(1)180 16-Dec-15 2015_12 "female sterile soma-dependent,recessive" egg FBgn0034745 CG4329 http://flybase.net/reports/FBgn0034745.html FBgn0044625 protein_coding_gene 0007605=sensory perception of sound anon-WO0140519.244 "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG4329 16-Dec-15 2015_12 ENSMUSG00000028730 ENSG00000164012 "auditory perception defective,neurophysiology defective" FBgn0032055 CG13091 http://flybase.net/reports/FBgn0032055.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity CT32316 "IPR026055=Fatty acyl-CoA reductase, IPR013120=Male sterility, NAD-binding, IPR016040=NAD(P)-binding domain" CG13091 16-Dec-15 2015_12 viable FBgn0033408 CG8800 http://flybase.net/reports/FBgn0033408.html protein_coding_gene "IPR001611=Leucine-rich repeat, IPR025875=Leucine rich repeat 4" CG8800 16-Dec-15 2015_12 ENSDARG00000034042(zgc:92542) ENSXETG00000000061(TGas099a14.1) ENSMUSG00000042523(Dnalc1) ENSG00000119661(DNAL1) viable FBgn0014168 fs(1)5Da fs(1)5Da http://flybase.net/reports/FBgn0014168.html gene unnamed 16-Dec-15 2015_12 "ovariole,germarium,follicle cell" FBgn0267438 CR45788 http://flybase.net/reports/FBgn0267438.html non_protein_coding_gene CR45788 16-Dec-15 2015_12 FBgn0034542 Fem-1 Fem-1 http://flybase.net/reports/FBgn0034542.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0051438=regulation of ubiquitin-protein transferase activity "CG9025, dFEM-1" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG9025 16-Dec-15 2015_12 ENSDARG00000062636(fem1b) ENSXETG00000007817(FEM1B) ENSMUSG00000032244(Fem1b) ENSG00000169018(FEM1B) viable FBgn0036926 CG7646 http://flybase.net/reports/FBgn0036926.html "FBgn0025545, FBgn0062911" protein_coding_gene 0005509=calcium ion binding "BcDNA:RH69723, anon-EST:Posey160" "IPR018247=EF-Hand 1, calcium-binding site, IPR028846=Recoverin family, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG7646 16-Dec-15 2015_12 WBGene00003564(ncs-2) viable FBgn0069133 mde mesoderm-excluded http://flybase.net/reports/FBgn0069133.html gene 0001707=mesoderm formation 16-Dec-15 2015_12 FBgn0065430 l(2)SH1496 lethal (2) SH1496 http://flybase.net/reports/FBgn0065430.html gene l(2)SH2 1496 16-Dec-15 2015_12 "lethal,recessive" FBgn0033925 CG8617 http://flybase.net/reports/FBgn0033925.html protein_coding_gene 0016272=prefoldin complex CG8617 16-Dec-15 2015_12 FBgn0041626 Or19a Odorant receptor 19a http://flybase.net/reports/FBgn0041626.html FBgn0042176 protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "Or19a-1, DOR37, 19a, CG18859, 19A.1" "IPR004117=Olfactory receptor, Drosophila" CG18859 16-Dec-15 2015_12 DRSC20684 K 0.507266739 0.01447537 -0.259516503 0.568276721 -5.364766097 -2.856164402 FBgn0260758 CG42556 http://flybase.net/reports/FBgn0260758.html "FBan0015133, FBgn0032619" protein_coding_gene 0009235=cobalamin metabolic process CG15133 IPR019362=Methylmalonic aciduria and homocystinuria type D protein CG42556 16-Dec-15 2015_12 viable FBgn0085730 CG42228 http://flybase.net/reports/FBgn0085730.html FBan0041434 protein_coding_gene 16-Dec-15 2015_12 FBgn0043882 mdg3\ORF ORF http://flybase.net/reports/FBgn0043882.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0015074=DNA integration mdg3NC "IPR000477=Reverse transcriptase domain, IPR001584=Integrase, catalytic core, IPR003034=SAP domain, IPR012337=Ribonuclease H-like domain, IPR001878=Zinc finger, CCHC-type, IPR021109=Aspartic peptidase domain" 16-Dec-15 2015_12 FBgn0037561 CG9630 http://flybase.net/reports/FBgn0037561.html protein_coding_gene "0003676=nucleic acid binding, 0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding" "DmRH16, cg9630" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR025313=Domain of unknown function DUF4217, IPR001650=Helicase, C-terminal, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site" CG9630 16-Dec-15 2015_12 ENSDARG00000009864(ddx55) YFL002C(SPB4) WBGene00013983(ZK512.2) ENSXETG00000005825(DDX55) ENSMUSG00000029389(Ddx55) ENSG00000111364(DDX55) "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0000955 fs(2)E2 female sterile (2) E2 http://flybase.net/reports/FBgn0000955.html gene fs2.2 16-Dec-15 2015_12 "female sterile,recessive" egg FBgn0023196 LPA-AT Lysophosphatidate Acyltransferase http://flybase.net/reports/FBgn0023196.html gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity unnamed 16-Dec-15 2015_12 FBgn0027137 l(3)88Ae lethal (3) 88Ae http://flybase.net/reports/FBgn0027137.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0266638 CR45145 http://flybase.net/reports/FBgn0266638.html non_protein_coding_gene CR45145 16-Dec-15 2015_12 FBgn0052213 CG32213 http://flybase.net/reports/FBgn0052213.html protein_coding_gene CG32213 16-Dec-15 2015_12 FBgn0027188 l(2)60A-D lethal (2) 60A-D http://flybase.net/reports/FBgn0027188.html gene 16-Dec-15 2015_12 lethal FBgn0025930 hip66 hb-interacting protein 66 http://flybase.net/reports/FBgn0025930.html gene 16-Dec-15 2015_12 FBgn0043876 micropia\polyprotein polyprotein http://flybase.net/reports/FBgn0043876.html transposable_element_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "IPR021109=Aspartic peptidase domain, IPR001878=Zinc finger, CCHC-type, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0086856 CG11555 http://flybase.net/reports/FBgn0086856.html "FBgn0031241, FBgn0017442" protein_coding_gene 0022008=neurogenesis "anon-21Ca, unnamed" CG11555 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,trichogen cell" FBgn0015240 Hr96 Hormone receptor-like in 96 http://flybase.net/reports/FBgn0015240.html protein_coding_gene "0003677=DNA binding, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding" "0042594=response to starvation, 0043401=steroid hormone mediated signaling pathway, 0070873=regulation of glycogen metabolic process, 0070328=triglyceride homeostasis, 0006355=regulation of transcription, DNA-templated, 0042632=cholesterol homeostasis" 0005634=nucleus "HR96, DHR96, dHR96, CG11783, Dhr96, NR1J1, hormone receptor-like in 96" "IPR013088=Zinc finger, NHR/GATA-type, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG11783 16-Dec-15 2015_12 "ENSDARG00000029766(nr1i2),ENSDARG00000070721(vdrb)" WBGene00000908(daf-12) "ENSXETG00000010658(VDR),ENSXETG00000018029(NR1I2),ENSXETG00000000307(NR1H2)" "ENSMUSG00000022479(Vdr),ENSMUSG00000022809(Nr1i2),ENSMUSG00000005677(Nr1i3)" "ENSG00000111424(VDR),ENSG00000144852(NR1I2),ENSG00000143257(NR1I3),ENSG00000025434(NR1H3)" larval stage && prepupal stage "lethal,chemical resistant,starvation stress response defective,viable,fertile,chemical sensitive,decreased cell size" "adult fat body,lipid particle,adult midgut epithelium,lipid particle, with Hr961.3',lipid particle, with Hr961.5'" FBgn0015721 ktub king tubby http://flybase.net/reports/FBgn0015721.html FBgn0034589 protein_coding_gene "0016059=deactivation of rhodopsin mediated signaling, 0006897=endocytosis, 0070328=triglyceride homeostasis, 0042593=glucose homeostasis, 0009744=response to sucrose, 0007608=sensory perception of smell" "0005737=cytoplasm, 0005634=nucleus, 0016028=rhabdomere" "tulp, Dtulp, king-tubby, CG9398, Tubby-like, ktub, king tubby, Tulp, ESTS:87D3S, tubby-like protein, 87D3S, King-tubby, TULP, D-tulp" "IPR025659=Tubby C-terminal-like domain, IPR018066=Tubby, C-terminal, conserved site, IPR000007=Tubby, C-terminal" CG9398 16-Dec-15 2015_12 "ENSDARG00000062165(LOC568677),ENSDARG00000062902" WBGene00006655(tub-1) "ENSXETG00000019686(TUB),ENSXETG00000001314(TULP3),ENSXETG00000000422(tulp1),ENSXETG00000021227(TULP2)" "ENSMUSG00000031028(Tub),ENSMUSG00000001521(Tulp3),ENSMUSG00000037446(Tulp1)" "ENSG00000166402(TUB),ENSG00000078246(TULP3),ENSG00000112041(TULP1)" "neuroanatomy defective,conditional,viable,stress response defective,chemical resistant,large body" "outer photoreceptor cell,conditional,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6" FBgn0001304 Kf1 Kynurenine formamidase 1 http://flybase.net/reports/FBgn0001304.html gene 0004061=arylformamidase activity 16-Dec-15 2015_12 FBgn0260954 CG42586 http://flybase.net/reports/FBgn0260954.html protein_coding_gene CG42586 16-Dec-15 2015_12 FBgn0014980 l(2)46Ca lethal (2) 46Ca http://flybase.net/reports/FBgn0014980.html gene "I, Group I" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0086209 su(comp)3L-1 http://flybase.net/reports/FBgn0086209.html gene 16-Dec-15 2015_12 FBgn0267616 CR45954 http://flybase.net/reports/FBgn0267616.html non_protein_coding_gene CR45954 16-Dec-15 2015_12 FBgn0032402 CG14945 http://flybase.net/reports/FBgn0032402.html protein_coding_gene "0047396=glycosylphosphatidylinositol diacylglycerol-lyase activity, 0008081=phosphoric diester hydrolase activity" 0006650=glycerophospholipid metabolic process cg14945 "IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR003633=Phospholipase C, variant-surface-glycoprotein" CG14945 16-Dec-15 2015_12 viable FBgn0065575 l(2)SH0954 lethal (2) SH0954 http://flybase.net/reports/FBgn0065575.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013452 fs(2)R2.503 fs(2)R2.503 http://flybase.net/reports/FBgn0013452.html gene unnamed 16-Dec-15 2015_12 "female sterile,recessive" FBgn0036341 Syx13 Syntaxin 13 http://flybase.net/reports/FBgn0036341.html FBgn0010751 protein_coding_gene "0005515=protein binding, 0005484=SNAP receptor activity, 0000149=SNARE binding" "0007269=neurotransmitter secretion, 0000281=mitotic cytokinesis, 0007067=mitotic nuclear division, 0007143=female meiotic division, 0016081=synaptic vesicle docking, 0006906=vesicle fusion, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0007110=meiosis I cytokinesis, 0007140=male meiosis" "0031201=SNARE complex, 0005886=plasma membrane" "syntaxin, syx13, Syntaxin13, l(3)01470, syntaxin 13, Syx20, dSyntaxin13, CG11278, SYN13, Dm Syx13, Syntaxin, ff16, Syx, ff16 (69D1-70A2), syntaxin13, DmSyx13" "IPR000727=Target SNARE coiled-coil homology domain, IPR010989=t-SNARE, IPR006012=Syntaxin/epimorphin, conserved site" CG11278 16-Dec-15 2015_12 "lethal,recessive,male sterile,female sterile,visible,meiotic cell cycle defective,mitotic cell cycle defective,viable" "polytene chromosome chromocenter,chaeta,meiotic cell cycle | male,meiotic cell cycle | female,meiosis & nuclear chromosome | male,meiotic anaphase I | male,meiotic metaphase II | male,meiotic telophase II | male,spermatozoon,onion stage spermatid,egg chamber,ovariole,nurse cell,karyosome,oocyte & spindle,oocyte,mitotic cell cycle,mitotic metaphase,mitotic cell cycle & spindle,mitotic cell cycle & nuclear chromosome" FBgn0266678 CR45168 http://flybase.net/reports/FBgn0266678.html non_protein_coding_gene CR45168 16-Dec-15 2015_12 FBgn0032315 CG14069 http://flybase.net/reports/FBgn0032315.html protein_coding_gene 0005125=cytokine activity 0007165=signal transduction CG14069 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0259754 ms(2)Fra-15 http://flybase.net/reports/FBgn0259754.html gene "0051276=chromosome organization, 0007283=spermatogenesis" 16-Dec-15 2015_12 male sterile "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,spermatozoon" FBgn0011565 boas beads on a string http://flybase.net/reports/FBgn0011565.html gene 16-Dec-15 2015_12 "female sterile,recessive" ovary FBgn0001358 l(1)1EFg lethal (1) 1EFg http://flybase.net/reports/FBgn0001358.html gene l(1)BA7 16-Dec-15 2015_12 lethal FBgn0010060 M(2)33d M(2)33d http://flybase.net/reports/FBgn0010060.html gene 16-Dec-15 2015_12 FBgn0011137 l(1)Q212 lethal (1) Q212 http://flybase.net/reports/FBgn0011137.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0065694 l(2)SH0639 lethal (2) SH0639 http://flybase.net/reports/FBgn0065694.html gene l(2)SH2 0639 16-Dec-15 2015_12 "lethal,recessive" FBgn0023027 l(2)CA8 lethal (2) CA8 http://flybase.net/reports/FBgn0023027.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267316 CR45752 http://flybase.net/reports/FBgn0267316.html non_protein_coding_gene CR45752 16-Dec-15 2015_12 FBgn0013393 anon-64Ba anon-64Ba http://flybase.net/reports/FBgn0013393.html gene 16-Dec-15 2015_12 FBgn0265760 CR44567 http://flybase.net/reports/FBgn0265760.html non_protein_coding_gene CR44567 16-Dec-15 2015_12 FBgn0267950 CR46230 http://flybase.net/reports/FBgn0267950.html non_protein_coding_gene lincRNA.497 CR46230 16-Dec-15 2015_12 FBgn0043027 l(2)42Ec lethal (2) 42Ec http://flybase.net/reports/FBgn0043027.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005564 Shal Shaker cognate l http://flybase.net/reports/FBgn0005564.html "FBgn0003385, FBgn0003394" protein_coding_gene "0005251=delayed rectifier potassium channel activity, 0005250=A-type (transient outward) potassium channel activity, 0005249=voltage-gated potassium channel activity" "0051260=protein homooligomerization, 0006813=potassium ion transport, 0055085=transmembrane transport, 0007268=synaptic transmission" "0008076=voltage-gated potassium channel complex, 0016021=integral component of membrane, 0005886=plasma membrane" "Kv4, Sh-l, shal, Shaker cognate L, Shaker-like, Shaker cognate 1, Shl, DNK[[v]]4, CG9262, dShal" "IPR003091=Potassium channel, IPR003975=Potassium channel, voltage dependent, Kv4, IPR021645=Shal-type voltage-gated potassium channels, IPR024587=Potassium channel, voltage dependent, Kv4, C-terminal, IPR028325=Voltage-gated potassium channel, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR011333=POZ domain, IPR005821=Ion transport domain, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR000210=BTB/POZ domain, IPR003968=Potassium channel, voltage dependent, Kv" CG9262 16-Dec-15 2015_12 "ENSDARG00000032799(kcnd2),ENSDARG00000056101(kcnd3)" WBGene00022240(shl-1) "ENSXETG00000013577(KCND3),ENSXETG00000023771(KCND1)" "ENSMUSG00000060882(Kcnd2),ENSMUSG00000040896(Kcnd3),ENSMUSG00000009731(Kcnd1)" "ENSG00000184408(KCND2),ENSG00000171385(KCND3),ENSG00000102057(KCND1)" "viable,fertile,neurophysiology defective,locomotor behavior defective,grooming behavior defective,chemical conditional" "embryonic/larval neuron,motor neuron | embryonic stage" FBgn0005359 Su(wa)B2 Suppressor of white-apricot B on 2 http://flybase.net/reports/FBgn0005359.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0021779 l(3)95Ca lethal (3) 95Ca http://flybase.net/reports/FBgn0021779.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032026 CG7627 http://flybase.net/reports/FBgn0032026.html protein_coding_gene "0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0008559=xenobiotic-transporting ATPase activity, 0005524=ATP binding" "0042060=wound healing, 0055085=transmembrane transport" "0043190=ATP-binding cassette (ABC) transporter complex, 0005886=plasma membrane" Dme_CG7627 "IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG7627 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) "viable,fertile" FBgn0030364 CG15735 http://flybase.net/reports/FBgn0030364.html FBgn0047226 protein_coding_gene 0016070=RNA metabolic process 0005634=nucleus BcDNA:LD05893 IPR019181=Anticodon-binding domain CG15735 16-Dec-15 2015_12 "ENSDARG00000028848(zgc:85812),ENSDARG00000045940(lsm12)" YHR121W(LSM12) ENSXETG00000003371(LSM12) ENSMUSG00000020922(Lsm12) ENSG00000161654(LSM12) viable FBgn0283426 acal http://flybase.net/reports/FBgn0283426.html non_protein_coding_gene "0046329=negative regulation of JNK cascade, 0007391=dorsal closure" CR46278 CR46278 16-Dec-15 2015_12 FBgn0039341 CG5112 http://flybase.net/reports/FBgn0039341.html protein_coding_gene "0017064=fatty acid amide hydrolase activity, 0016884=carbon-nitrogen ligase activity, with glutamine as amido-N-donor" 0005811=lipid particle "IPR020556=Amidase, conserved site, IPR000120=Amidase, IPR023631=Amidase signature domain" CG5112 16-Dec-15 2015_12 YDR242W(AMD2) ENSMUSG00000034171(Faah) "viable,fertile" FBgn0050290 Ppcdc Phosphopantothenoylcysteine decarboxylase http://flybase.net/reports/FBgn0050290.html FBgn0063143 protein_coding_gene "0003824=catalytic activity, 0004633=phosphopantothenoylcysteine decarboxylase activity" 0015937=coenzyme A biosynthetic process "dPPCDC, Dromel_CG30290_FBtr0071672_cx9c_mORF, PPCDC, CG30290, BcDNA:LD37882, (R)-4'-phospho-N-pantothenoylcysteine decarboxylase" IPR003382=Flavoprotein CG30290 16-Dec-15 2015_12 ENSDARG00000033020(ppcdc) WBGene00009138(F25H9.6) ENSXETG00000010670(PPCDC) ENSMUSG00000063849(Ppcdc) ENSG00000138621(PPCDC) "viable,visible" trichogen cell DRSC03886 I 0.083839311 3.038274453 -0.220046697 0.931310059 -0.325521075 0.336648198 FBgn0001365 l(1)1Fd lethal (1) 1Fd http://flybase.net/reports/FBgn0001365.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,maternal effect,some die during pupal stage,lethal,recessive,germline clone" "segment,germline clone" FBgn0261445 sgl sugarless http://flybase.net/reports/FBgn0261445.html "FBgn0010851, FBgn0002456, FBgn0010929, FBgn0015500, FBgn0086381" protein_coding_gene "0003979=UDP-glucose 6-dehydrogenase activity, 0051287=NAD binding" "0007427=epithelial cell migration, open tracheal system, 0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior, 0015012=heparan sulfate proteoglycan biosynthetic process, 0007509=mesoderm migration involved in gastrulation, 0007507=heart development, 0016055=Wnt signaling pathway, 0055114=oxidation-reduction process, 0007166=cell surface receptor signaling pathway, 0006024=glycosaminoglycan biosynthetic process, 0015014=heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, 0008543=fibroblast growth factor receptor signaling pathway, 0007224=smoothened signaling pathway, 0007367=segment polarity determination, 0007428=primary branching, open tracheal system, 0042048=olfactory behavior, 0016319=mushroom body development, 0030206=chondroitin sulfate biosynthetic process" "l(3)08310, CG10072, BG01214, UDP-GlcDH, lethal(3)SG9, Sugarless, Sgl, unnamed, Distal W5.4 Group XIII, UDP-glucose 6-dehydrogenase, XIII, UDPGDH, l(3)10503, l(3)65CEd, kiwi, UDP-glucose dehydrogenase, suppenkasper, sl, ska, 8310, l(3)SG9, l(3)05007" "IPR014027=UDP-glucose/GDP-mannose dehydrogenase, C-terminal, IPR028356=UDP-glucose 6-dehydrogenase, eukaryotic type, IPR016040=NAD(P)-binding domain, IPR001732=UDP-glucose/GDP-mannose dehydrogenase, N-terminal, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR014026=UDP-glucose/GDP-mannose dehydrogenase, dimerisation, IPR017476=UDP-glucose/GDP-mannose dehydrogenase" CG10072 16-Dec-15 2015_12 ENSDARG00000019838(ugdh) WBGene00005022(sqv-4) "ENSXETG00000016526(BC075574.1),ENSXETG00000012846(ugdh)" ENSMUSG00000029201(Ugdh) ENSG00000109814(UGDH) " embryonic stage | stage 17 , embryonic stage | stage <4 , larval stage | third instar , embryonic stage | stage >9 , embryonic stage | stage 16-17 , embryonic stage | early , embryonic stage | stage 13 , embryonic stage , embryonic stage | stage 9-14 , embryonic stage | extended germ band " " embryonic/larval pharynx

,

ubiquitous , imaginal disc

, cephalic furrow | surrounding

, embryonic/larval hindgut

, morphogenetic furrow

, embryonic/larval proventriculus

, embryonic/larval midgut

, amnioserosa | presumptive

, mesoderm

" FBgn0085677 CG41538 http://flybase.net/reports/FBgn0085677.html FBan0041538 protein_coding_gene 16-Dec-15 2015_12 FBgn0002919 NaCP37B Na channel protein 37B http://flybase.net/reports/FBgn0002919.html gene 0005248=voltage-gated sodium channel activity 0035725=sodium ion transmembrane transport 0005886=plasma membrane DIC37 "IPR028820=Sodium channel protein 60E, IPR005821=Ion transport domain" 16-Dec-15 2015_12 FBgn0022335 f36 f36 http://flybase.net/reports/FBgn0022335.html gene 0007140=male meiosis 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" "spermatocyte,primary spermatocyte cyst,germarium,ovary,testis,ganglion" FBgn0024599 sine sine http://flybase.net/reports/FBgn0024599.html gene 0001746=Bolwig's organ morphogenesis 16-Dec-15 2015_12 viable "Bolwig nerve,Bolwig organ" FBgn0000919 fs(1)ne5 female sterile (1) no eggs 5 http://flybase.net/reports/FBgn0000919.html gene "ne5, fs(1)ne[5]" 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,chorion,stage S10A oocyte,stage S10B oocyte" FBgn0260713 CG42544 http://flybase.net/reports/FBgn0260713.html protein_coding_gene HCD12266 CG42544 16-Dec-15 2015_12 FBgn0029709 CHOp24 CHOp24 http://flybase.net/reports/FBgn0029709.html protein_coding_gene 0005215=transporter activity "0090263=positive regulation of canonical Wnt signaling pathway, 0061357=positive regulation of Wnt protein secretion, 0048193=Golgi vesicle transport, 0000003=reproduction, 0070863=positive regulation of protein exit from endoplasmic reticulum, 0006888=ER to Golgi vesicle-mediated transport, 0035220=wing disc development, 0048042=regulation of post-mating oviposition" "0012505=endomembrane system, 0030126=COPI vesicle coat, 0016021=integral component of membrane" "emp24, Emp24, p24/p24beta1, CG3564, p24" "IPR009038=GOLD domain, IPR015720=TMP21-related" CG3564 16-Dec-15 2015_12 ENSDARG00000026908(tmed2) YGL200C(EMP24) WBGene00004766(sel-9) ENSXETG00000005824(tmed2) "ENSMUSG00000029390(Tmed2),ENSMUSG00000074460(Gm10698)" ENSG00000086598(TMED2) "viable,visible,lethal,female semi-sterile" "chaeta,supernumerary,wing margin,somatic clone" FBgn0264897 CG44088 http://flybase.net/reports/FBgn0264897.html protein_coding_gene CG44088 16-Dec-15 2015_12 FBgn0021823 l(2)k16204 lethal (2) k16204 http://flybase.net/reports/FBgn0021823.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261791 SNRPG Small nuclear ribonucleoprotein G http://flybase.net/reports/FBgn0261791.html "FBgn0030765, FBgn0047022, FBgn0062985, FBgn0022964" protein_coding_gene 0044822=poly(A) RNA binding "0007052=mitotic spindle organization, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005732=small nucleolar ribonucleoprotein complex, 0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus" "Small ribonucleoprotein G, BcDNA:RE61341, G-Sm, HD10913, dG, CG9742, BcDNA:RH35475, SmG, Small ribonucleoprotein particle protein SmG, G, snRNPG" "IPR001163=LSM domain, eukaryotic/archaea-type, IPR017132=Sm-like protein Lsm7/snRNP-G, IPR010920=LSM domain" CG9742 16-Dec-15 2015_12 ENSDARG00000040125 YFL017W-A(SMX2) WBGene00004920(snr-7) ENSXETG00000008512(SNRPG) ENSMUSG00000057278(Snrpg) ENSG00000143977(SNRPG) FBgn0011736 wad waddell http://flybase.net/reports/FBgn0011736.html gene wdel 16-Dec-15 2015_12 cleavage stage embryo FBgn0002977 obl oblique wings http://flybase.net/reports/FBgn0002977.html gene 16-Dec-15 2015_12 "visible,recessive,viable,good,male,male fertile,female,reduced,female fertile,female semi-sterile,body color defective" wing FBgn0034326 CG18540 http://flybase.net/reports/FBgn0034326.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG18540 16-Dec-15 2015_12 viable FBgn0265824 CR44613 http://flybase.net/reports/FBgn0265824.html non_protein_coding_gene lincRNA.64 CR44613 16-Dec-15 2015_12 FBgn0260339 GSd434 http://flybase.net/reports/FBgn0260339.html gene 16-Dec-15 2015_12 lethal FBgn0001039 fs(3)H23 female sterile (3) H23 http://flybase.net/reports/FBgn0001039.html gene 16-Dec-15 2015_12 female sterile egg chamber FBgn0036488 CG6878 http://flybase.net/reports/FBgn0036488.html protein_coding_gene 1903146=regulation of mitochondrion degradation Romo1 IPR018450=Reactive oxygen species modulator 1 CG6878 16-Dec-15 2015_12 ENSDARG00000038076(zgc:73345) YPL098C(MGR2) "WBGene00008860(rmo-1),WBGene00050893(Y94A7B.11)" ENSXETG00000025474(ROMO1) "ENSMUSG00000067847(Romo1),ENSMUSG00000049231(Gm12497)" ENSG00000125995(ROMO1) viable FBgn0036757 Ir75a Ionotropic receptor 75a http://flybase.net/reports/FBgn0036757.html protein_coding_gene "0015276=ligand-gated ion channel activity, 0004984=olfactory receptor activity, 0004970=ionotropic glutamate receptor activity, 0005230=extracellular ligand-gated ion channel activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007605=sensory perception of sound, 0050907=detection of chemical stimulus involved in sensory perception" "0016021=integral component of membrane, 0071683=sensory dendrite, 0005887=integral component of plasma membrane" "DmelIR75a, IR75a, IR75abc, CG14585, ionotropic receptor 75a" "IPR030406=Ionotropic receptor 75-related, IPR001320=Ionotropic glutamate receptor" CG14585 16-Dec-15 2015_12 "auditory perception defective,viable" FBgn0034789 PIP5K59B Phosphatidylinositol 4-phosphate 5-kinase at 59B http://flybase.net/reports/FBgn0034789.html FBgn0034790 protein_coding_gene 0016308=1-phosphatidylinositol-4-phosphate 5-kinase activity "0071482=cellular response to light stimulus, 0010513=positive regulation of phosphatidylinositol biosynthetic process, 0016310=phosphorylation, 0007603=phototransduction, visible light, 0008582=regulation of synaptic growth at neuromuscular junction" 0035997=rhabdomere microvillus membrane "CG17281, CG3682, PIP5K59B, dPIP5K, PI4P5K, PIP5K 59B" "IPR023610=Phosphatidylinositol-4-phosphate 5-kinase, IPR002498=Phosphatidylinositol-4-phosphate 5-kinase, core, IPR016034=Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup, IPR027483=Phosphatidylinositol-4-phosphate 5-kinase, C-terminal, IPR027484=Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain" CG3682 16-Dec-15 2015_12 "ENSDARG00000009442(si:ch211-243a15.1),ENSDARG00000024642(zgc:158838),ENSDARG00000006508(zgc:92316),ENSDARG00000002614(pip5k1a),ENSDARG00000044295(pip5k1b)" YDR208W(MSS4) WBGene00004087(ppk-1) "ENSXETG00000019412(pip5k1a),ENSXETG00000006418(PIP5K1C)" "ENSMUSG00000034902(Pip5k1c),ENSMUSG00000028126(Pip5k1a),ENSMUSG00000024867(Pip5k1b)" "ENSG00000186111(PIP5K1C),ENSG00000143398(PIP5K1A),ENSG00000180764,ENSG00000107242(PIP5K1B)" viable embryonic/larval neuromuscular junction | third instar larval stage FBgn0085522 CG40818 http://flybase.net/reports/FBgn0085522.html FBan0040818 protein_coding_gene 16-Dec-15 2015_12 FBgn0019762 l(1)71B lethal (1) 71B http://flybase.net/reports/FBgn0019762.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050358 CG30358 http://flybase.net/reports/FBgn0050358.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031332 CG5556 http://flybase.net/reports/FBgn0031332.html protein_coding_gene 0016787=hydrolase activity 0008152=metabolic process "IPR006439=HAD hydrolase, subfamily IA, IPR023214=HAD-like domain" CG5556 16-Dec-15 2015_12 FBgn0042185 CG18769 http://flybase.net/reports/FBgn0042185.html FBgn0035705 protein_coding_gene 0005739=mitochondrion CG8352 "IPR006769=Coiled-coil domain containing protein 109, C-terminal, IPR003034=SAP domain" CG18769 16-Dec-15 2015_12 ENSDARG00000026804(zgc:153607) WBGene00019296(K02B2.3) "ENSXETG00000006157(CCDC109A),ENSXETG00000021086(CCDC109B)" ENSMUSG00000009647(Ccdc109a) ENSG00000156026(MCU) "viable,fertile" FBgn0266929 CR45380 http://flybase.net/reports/FBgn0266929.html non_protein_coding_gene CR45380 16-Dec-15 2015_12 FBgn0016860 l(1)N8 lethal (1) N8 http://flybase.net/reports/FBgn0016860.html gene N8 16-Dec-15 2015_12 "lethal,recessive" FBgn0001717 l(1)ESHS38 lethal (1) ESHS38 http://flybase.net/reports/FBgn0001717.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022169 l(2)k05448 lethal (2) k05448 http://flybase.net/reports/FBgn0022169.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015622 Cnx99A Calnexin 99A http://flybase.net/reports/FBgn0015622.html FBgn0039660 protein_coding_gene "0051082=unfolded protein binding, 0005509=calcium ion binding" "0001895=retina homeostasis, 0016063=rhodopsin biosynthetic process, 0010522=regulation of calcium ion transport into cytosol, 0006457=protein folding" "0012505=endomembrane system, 0005886=plasma membrane, 0097038=perinuclear endoplasmic reticulum, 0005783=endoplasmic reticulum" "calnexin99A, Cnx, calnexin, Cnx99a, cnx, Calnexin, CG11958" "IPR009033=Calreticulin/calnexin, P domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001580=Calreticulin/calnexin, IPR018124=Calreticulin/calnexin, conserved site" CG11958 16-Dec-15 2015_12 "ENSDARG00000037488(canx),ENSDARG00000009315(clgn)" YAL058W(CNE1) WBGene00000567(cnx-1) ENSXETG00000008408(canx) "ENSMUSG00000020368(Canx),ENSMUSG00000002190(Clgn)" "ENSG00000127022(CANX),ENSG00000153132(CLGN)" embryonic stage " embryonic central nervous system

, peripheral nervous system

" "viable,neurophysiology defective,lethal,visible,partially lethal - majority die,some die during pupal stage" "retina,conditional,rhabdomere of eye photoreceptor cell,endoplasmic reticulum,Golgi apparatus,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,medial longitudinal fascicle,intermediate longitudinal fascicle,ventral nerve cord commissure,ventral nerve cord,trichogen cell,mesothoracic tergum" FBgn0263324 CR43405 http://flybase.net/reports/FBgn0263324.html non_protein_coding_gene CG43405 CR43405 16-Dec-15 2015_12 FBgn0086201 S(ls)1 http://flybase.net/reports/FBgn0086201.html gene 16-Dec-15 2015_12 FBgn0016650 Lgr1 Leucine-rich repeat-containing G protein-coupled receptor 1 http://flybase.net/reports/FBgn0016650.html protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity, 0042562=hormone binding, 0016500=protein-hormone receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0009755=hormone-mediated signaling pathway, 0019933=cAMP-mediated signaling" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "DLGR-1, Fsh, dLGR1, Fsh-Tsh-like receptor, Leu-rich repeats-containing G protein-coupled receptor, DLGR1, FSH-TSH, Fsh/CG7665, CG7665, Glycoprotein A2/Glycoprotein B5 receptor, unnamed, RH44949p, LGR1, TSH, FSH, LH/CG receptor" "IPR001611=Leucine-rich repeat, IPR017452=GPCR, rhodopsin-like, 7TM, IPR002131=Glycoprotein hormone receptor family, IPR000276=G protein-coupled receptor, rhodopsin-like" CG7665 16-Dec-15 2015_12 "ENSDARG00000037195,ENSDARG00000071494(fshr),ENSDARG00000026081(lhcgr)" WBGene00008239(fshr-1) ENSXETG00000010035(TSHR) "ENSMUSG00000024107(Lhcgr),ENSMUSG00000020963(Tshr),ENSMUSG00000032937(Fshr)" "ENSG00000138039(LHCGR),ENSG00000170820(FSHR),ENSG00000165409(TSHR)" "viable,visible" mesothoracic tergum FBgn0001672 l(1)EN9 lethal (1) from Eugene Nonautonomous 9 http://flybase.net/reports/FBgn0001672.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval fat body,Malpighian tubule,embryonic/larval salivary gland,embryonic/larval cuticle" FBgn0040110 l(3)tk12 lethal (3) tk12 http://flybase.net/reports/FBgn0040110.html gene tk12 16-Dec-15 2015_12 "lethal,recessive" FBgn0024315 Picot Picot http://flybase.net/reports/FBgn0024315.html protein_coding_gene "0005316=high-affinity inorganic phosphate:sodium symporter activity, 0015114=phosphate ion transmembrane transporter activity" "0035435=phosphate ion transmembrane transport, 0006817=phosphate ion transport" 0016021=integral component of membrane "picot, MFS8, CG8098, putative inorganic phosphate cotransporter" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain, IPR004745=Na-dependent inorganic phosphate cotransporter" CG8098 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "lethal,viable" DRSC07508 I -0.550793728 1.57249148 1.122309429 0.412384486 -0.612761317 -0.264277534 FBgn0001063 Fs(3)Pud Female sterile (3) Pudur http://flybase.net/reports/FBgn0001063.html gene 0009792=embryo development ending in birth or egg hatching "Fs(3)Sz29, Pud, Fs(3)Pudur" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0034867 CG13557 http://flybase.net/reports/FBgn0034867.html protein_coding_gene CG13557 16-Dec-15 2015_12 viable FBgn0026630 nes nessy http://flybase.net/reports/FBgn0026630.html protein_coding_gene 0071617=lysophospholipid acyltransferase activity "0007009=plasma membrane organization, 0008354=germ cell migration, 0007291=sperm individualization, 0030258=lipid modification" "0005886=plasma membrane, 0016020=membrane" "Nes, Nessy, CG9655" "IPR004299=Membrane bound O-acyl transferase, MBOAT" CG9655 16-Dec-15 2015_12 WBGene00020115(mboa-6) ENSXETG00000023913() ENSMUSG00000004270(Lpcat3) ENSG00000111684(LPCAT3) " embryonic stage | stage 6-7 , embryonic stage -- adult stage , embryonic stage , embryonic stage | early , embryonic stage | stage 7-12 , embryonic stage | stage >=13 " " mesectoderm anlage

, cephalic furrow

,

ubiquitous , mesoderm

, visceral mesoderm

, endoderm

" "viable,fertile" embryo FBgn0036416 CG7924 http://flybase.net/reports/FBgn0036416.html protein_coding_gene "IPR002350=Kazal domain, IPR002989=Mycobacterial pentapeptide repeat" CG7924 16-Dec-15 2015_12 viable FBgn0029763 Usp16-45 Ubiquitin specific protease 16/45 http://flybase.net/reports/FBgn0029763.html protein_coding_gene "0008270=zinc ion binding, 0004843=ubiquitin-specific protease activity" "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" "Q9W4C3, CG4165, Usp45, Usp16, unnamed, USP45" "IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain, IPR001607=Zinc finger, UBP-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR018200=Ubiquitin specific protease, conserved site" CG4165 16-Dec-15 2015_12 ENSDARG00000060633(usp16) WBGene00013506(usp-3) "ENSMUSG00000040455(Usp45),ENSMUSG00000025616(Usp16)" "ENSG00000156256(USP16),ENSG00000123552(USP45)" "visible,partially lethal - majority die,some die during pupal stage,short lived,locomotor behavior defective" "trichogen cell,mesothoracic tergum" FBgn0036612 CG4998 http://flybase.net/reports/FBgn0036612.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH66 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG4998 16-Dec-15 2015_12 "WBGene00006625(try-7),WBGene00006624(try-6)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC22911 K 0.058881863 0.681098197 -0.56995951 0.144411574 -0.828105717 -2.002806659 FBgn0011530 l(2)06424 lethal (2) 06424 http://flybase.net/reports/FBgn0011530.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028906 CG17341 http://flybase.net/reports/FBgn0028906.html protein_coding_gene 0005515=protein binding 0005654=nucleoplasm BG:DS01523.1 IPR008845=Sporozoite P67 surface antigen CG17341 16-Dec-15 2015_12 ENSDARG00000037607(zgc:158791) "ENSXETG00000006621(C20orf112),ENSXETG00000020548(NOL4)" "ENSMUSG00000061411(8430427H17Rik),ENSMUSG00000041923(Nol4)" "ENSG00000101746(NOL4),ENSG00000197183(C20orf112)" FBgn0039081 Irk2 Inwardly rectifying potassium channel 2 http://flybase.net/reports/FBgn0039081.html FBgn0039082 protein_coding_gene "0005242=inward rectifier potassium channel activity, 0015467=G-protein activated inward rectifier potassium channel activity" "0006813=potassium ion transport, 0035220=wing disc development, 0090099=negative regulation of decapentaplegic signaling pathway, 0042391=regulation of membrane potential, 0048812=neuron projection morphogenesis" 0016021=integral component of membrane "CG4370, dKirII, CG10180, dKir, irk2" "IPR016449=Potassium channel, inwardly rectifying, Kir, IPR013518=Potassium channel, inwardly rectifying, Kir, cytoplasmic, IPR014756=Immunoglobulin E-set" CG4370 16-Dec-15 2015_12 "ENSDARG00000060259(zgc:162160),ENSDARG00000058985,ENSDARG00000061014,ENSDARG00000061636(LOC100334285),ENSDARG00000059747(si:dkey-106c17.3),ENSDARG00000062217(LOC557095),ENSDARG00000059822(LOC569146)" "ENSXETG00000017827(),ENSXETG00000026072(KCNJ5),ENSXETG00000023557(KCNJ6),ENSXETG00000021717(KCNJ3),ENSXETG00000028069(),ENSXETG00000022975(),ENSXETG00000007492(KCNJ12),ENSXETG00000022962(KCNJ2),ENSXETG00000006360(KCNJ4)" "ENSMUSG00000042529(Kcnj12),ENSMUSG00000041695(Kcnj2),ENSMUSG00000044216(Kcnj4),ENSMUSG00000058743(Kcnj14)" "ENSG00000184185(KCNJ12),ENSG00000123700(KCNJ2),ENSG00000168135(KCNJ4),ENSG00000182324(KCNJ14),ENSG00000162728(KCNJ9),ENSG00000120457(KCNJ5)" "visible,size defective,cell death defective,partially lethal - majority die,some die during larval stage,cold sensitive,lethal,viable" "wing,wing vein,wing hinge,wing margin bristle,wing blade,wing vein L5,posterior crossvein,wing vein L2,wing vein L3,wing vein L4,wing disc | third instar larval stage" FBgn0024876 l(2)52Fe lethal (2) 52Fe http://flybase.net/reports/FBgn0024876.html gene E6.17 16-Dec-15 2015_12 lethal FBgn0005112 l(1)6 lethal (1) 6 http://flybase.net/reports/FBgn0005112.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065723 l(2)SH0566 lethal (2) SH0566 http://flybase.net/reports/FBgn0065723.html gene l(2)SH2 0566 16-Dec-15 2015_12 "lethal,recessive" FBgn0030398 Cpr11B Cuticular protein 11B http://flybase.net/reports/FBgn0030398.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG2555, DmelCpr11B" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG2555 16-Dec-15 2015_12 "viable,fertile" FBgn0005686 rug rugged http://flybase.net/reports/FBgn0005686.html gene 0048749=compound eye development 16-Dec-15 2015_12 "visible,recessive" "eye,ommatidium" FBgn0010075 Ms(2)M Male sterile (2) of Meyer http://flybase.net/reports/FBgn0010075.html gene Ms 16-Dec-15 2015_12 "male sterile,dominant,female fertile" FBgn0065686 l(2)SH0656 lethal (2) SH0656 http://flybase.net/reports/FBgn0065686.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035856 CG13679 http://flybase.net/reports/FBgn0035856.html FBgn0047158 protein_coding_gene BcDNA:RE17113 CG13679 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0050229 tRNA:CR30229 transfer RNA:CR30229 http://flybase.net/reports/FBgn0050229.html FBgn0060166 tRNA_gene 0033417=CUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna32-LeuAAG, CR30229, tRNA:L:AAG:AE002787-d, AE002787.trna49-LeuAAG" CR30229 16-Dec-15 2015_12 FBgn0014280 l(2)vsp lethal (2) very small puparia http://flybase.net/reports/FBgn0014280.html gene l(2)60A-G 16-Dec-15 2015_12 "lethal,recessive" FBgn0039684 Obp99d Odorant-binding protein 99d http://flybase.net/reports/FBgn0039684.html protein_coding_gene 0005549=odorant binding "0048102=autophagic cell death, 0002121=inter-male aggressive behavior, 0035071=salivary gland cell autophagic cell death, 0007606=sensory perception of chemical stimulus" 0005576=extracellular region "CG15505, DmelObp99d, 99d, Obp99c, CG155505" IPR006170=Pheromone/general odorant binding protein CG15505 16-Dec-15 2015_12 "behavior defective,recessive,viable" FBgn0267542 CR45882 http://flybase.net/reports/FBgn0267542.html non_protein_coding_gene CR45882 16-Dec-15 2015_12 FBgn0040128 l(2)22Ak lethal (2) 22Ak http://flybase.net/reports/FBgn0040128.html gene G 16-Dec-15 2015_12 "lethal,recessive" FBgn0028848 CG7311 http://flybase.net/reports/FBgn0028848.html FBgn0001129 protein_coding_gene 0004368=glycerol-3-phosphate dehydrogenase activity "0055114=oxidation-reduction process, 0006072=glycerol-3-phosphate metabolic process" "0005739=mitochondrion, 0009331=glycerol-3-phosphate dehydrogenase complex" "Gpo, alpha-GPO, GPO-2, GPO, BG:DS08249.2" "IPR000447=FAD-dependent glycerol-3-phosphate dehydrogenase, IPR006076=FAD dependent oxidoreductase" CG7311 16-Dec-15 2015_12 viable FBgn0053969 CG33969 http://flybase.net/reports/FBgn0053969.html "FBgn0036982, FBgn0052429, FBtr0078236, FBpp0077894, FBtr0078237, FBpp0077895" protein_coding_gene "CG5571, CG32429" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain" CG33969 16-Dec-15 2015_12 ENSMUSG00000040913(Fbxw4) ENSG00000107829(FBXW4) viable FBgn0002358 l(3)87Ef lethal (3) 87Ef http://flybase.net/reports/FBgn0002358.html gene "l(3)m32, m32" 16-Dec-15 2015_12 "lethal,recessive" FBgn0263999 CG43742 http://flybase.net/reports/FBgn0263999.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG43742 16-Dec-15 2015_12 FBgn0030525 CG10996 http://flybase.net/reports/FBgn0030525.html protein_coding_gene "0004034=aldose 1-epimerase activity, 0030246=carbohydrate binding" 0005975=carbohydrate metabolic process "IPR014718=Glycoside hydrolase-type carbohydrate-binding, subgroup, IPR011013=Galactose mutarotase-like domain, IPR008183=Aldose 1-/Glucose-6-phosphate 1-epimerase" CG10996 16-Dec-15 2015_12 ENSDARG00000057630(galm) "YHR210C(),YNR071C()" WBGene00015270(C01B4.6) ENSXETG00000009022(GALM) ENSMUSG00000035473(Galm) ENSG00000143891(GALM) viable FBgn0035244 ABCB7 http://flybase.net/reports/FBgn0035244.html FBgn0069053 protein_coding_gene "0015232=heme transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" "0015886=heme transport, 0016226=iron-sulfur cluster assembly, 0055085=transmembrane transport, 0006879=cellular iron ion homeostasis" "0005743=mitochondrial inner membrane, 0043190=ATP-binding cassette (ABC) transporter complex, 0016021=integral component of membrane" "CG7955, dABCB7" "IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR011527=ABC transporter type 1, transmembrane domain" CG7955 16-Dec-15 2015_12 ENSDARG00000062795(abcb7) YMR301C(ATM1) WBGene00022281(abtm-1) ENSXETG00000004572(ABCB7) ENSMUSG00000031333 ENSG00000131269(ABCB7) viable DRSC08603 K 0.323729714 -0.074946061 0.333887392 -0.409660091 2.039088893 -0.326704885 FBgn0028206 l(3)S012613a lethal (3) S012613a http://flybase.net/reports/FBgn0028206.html gene "0126/13, l(3)S012613" 16-Dec-15 2015_12 "lethal,recessive" FBgn0031630 CG15629 http://flybase.net/reports/FBgn0031630.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG15629 16-Dec-15 2015_12 "ENSDARG00000016233(zgc:76925),ENSDARG00000017794(sdr16c5),ENSDARG00000041873(si:dkey-221h15.4),ENSDARG00000012369(rdh10b)" "YDL114W(),YLR426W()" "ENSXETG00000005655(BC075474.1),ENSXETG00000011825(rdh10),ENSXETG00000017934(dhrs8),ENSXETG00000006425(BC087812.1)" "ENSMUSG00000071019(Sdr16c6),ENSMUSG00000028236(Sdr16c5)" viable FBgn0011457 l(3)neo20 lethal (3) neo20 http://flybase.net/reports/FBgn0011457.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003953 unp unexpanded http://flybase.net/reports/FBgn0003953.html gene 16-Dec-15 2015_12 "male fertile,viable,male,poor,female,visible" "wing,pronotum" FBgn0045471 Gr92a Gustatory receptor 92a http://flybase.net/reports/FBgn0045471.html "FBgn0045472, FBgn0051208" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 92D1, CG31208, DmGr92a, GR92a, Gr92D1" IPR013604=7TM chemoreceptor CG31208 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0266490 CG45089 http://flybase.net/reports/FBgn0266490.html protein_coding_gene Dromel_CG18624_FBtr0071140_uORF CG45089 16-Dec-15 2015_12 FBgn0040633 CG12451 http://flybase.net/reports/FBgn0040633.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027156 l(2)ch lethal (2) ch http://flybase.net/reports/FBgn0027156.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0024679 l(1)LefEM27 lethal (1) LefEM27 http://flybase.net/reports/FBgn0024679.html gene EM27 16-Dec-15 2015_12 FBgn0036314 CG10754 http://flybase.net/reports/FBgn0036314.html protein_coding_gene "0044822=poly(A) RNA binding, 0008270=zinc ion binding" "0000398=mRNA splicing, via spliceosome, 0070374=positive regulation of ERK1 and ERK2 cascade, 0022008=neurogenesis, 0007052=mitotic spindle organization, 0046579=positive regulation of Ras protein signal transduction" "0071013=catalytic step 2 spliceosome, 0005686=U2 snRNP, 0071011=precatalytic spliceosome, 0005681=spliceosomal complex" "IPR015880=Zinc finger, C2H2-like, IPR019134=Cactin, C-terminal, IPR003604=Zinc finger, U1-type, IPR000690=Zinc finger, C2H2-type matrin" CG10754 16-Dec-15 2015_12 ENSDARG00000021107(sf3a2) YDL043C(PRP11) WBGene00008683(F11A10.2) ENSXETG00000024943(sf3a2) ENSMUSG00000020211(Sf3a2) ENSG00000104897(SF3A2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,wing" DRSC09801 K -0.130920703 1.315523647 -1.258309124 -0.338081644 -1.85800193 -0.217056313 FBgn0020639 Lcp65Af Lcp65Af http://flybase.net/reports/FBgn0020639.html FBgn0035682 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Lcp-f, DmelLcp65Af, CG10533, DCP7, DMLCP65f" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG10533 16-Dec-15 2015_12 " embryonic stage , larval stage " FBgn0024642 l(2)k11560 lethal (2) k11560 http://flybase.net/reports/FBgn0024642.html gene 115/60 16-Dec-15 2015_12 "visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,trichome" FBgn0032996 CG17479 http://flybase.net/reports/FBgn0032996.html protein_coding_gene 16-Dec-15 2015_12 FBgn0250735 l(3)S023931 lethal (3) S023931 http://flybase.net/reports/FBgn0250735.html gene l(3)s023931 16-Dec-15 2015_12 lethal FBgn0260441 RpS12 Ribosomal protein S12 http://flybase.net/reports/FBgn0260441.html "FBgn0014027, FBgn0036339, FBan0011271, FBgn0011809, FBgn0064825" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "RS12, BcDNA:RH29995, putative ribosomal protein S12, RpS12E, Ribosomal protein gene 12, 40S ribosomal protein S12, CG11271, 40S ribosomal component, Ribosomal Protein S12, l(3)s2783, S12" "IPR000530=Ribosomal protein S12e, IPR029064=50S ribosomal protein L30e-like, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45" CG11271 16-Dec-15 2015_12 "lethal,recessive" DRSC11270 IEK -2.425239312 -2.203312862 0.146312604 -5.374508049 0.602711103 2.083385557 FBgn0060525 l(3)S101904b lethal (3) S101904b http://flybase.net/reports/FBgn0060525.html gene 1019/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262407 mir-308 mir-308 stem loop http://flybase.net/reports/FBgn0262407.html "FBgn0067696, FBgn0262244" miRNA_gene 0017148=negative regulation of translation "308, CR33612, miR-308, dme-mir-308, CR42951, mir-308" CR42951 16-Dec-15 2015_12 "visible,lethal,partially lethal - majority die" wing FBgn0005364 tr261 triangle 261 http://flybase.net/reports/FBgn0005364.html gene tr-261 16-Dec-15 2015_12 "crossvein,ectopic" FBgn0033769 CG8768 http://flybase.net/reports/FBgn0033769.html protein_coding_gene "0050662=coenzyme binding, 0003824=catalytic activity" "IPR016040=NAD(P)-binding domain, IPR010099=Epimerase family protein SDR39U1, IPR001509=NAD-dependent epimerase/dehydratase, N-terminal domain, IPR013549=Domain of unknown function DUF1731" CG8768 16-Dec-15 2015_12 ENSDARG00000068215(zgc:153633) ENSXETG00000016929(SDR39U1) ENSMUSG00000022223(Sdr39u1) ENSG00000100445(SDR39U1) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0265305 CR44278 http://flybase.net/reports/FBgn0265305.html non_protein_coding_gene lincRNA.274 CR44278 16-Dec-15 2015_12 FBgn0265265 CG32727 http://flybase.net/reports/FBgn0265265.html "FBgn0052727, FBgn0066957" protein_coding_gene anon-SAGE:Wang-041 IPR001623=DnaJ domain CG32727 16-Dec-15 2015_12 FBgn0264658 piddling piddling http://flybase.net/reports/FBgn0264658.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0028217 l(3)S008224 lethal (3) S008224 http://flybase.net/reports/FBgn0028217.html gene 0082/24 16-Dec-15 2015_12 "lethal,recessive" FBgn0265262 Vha68-1 Vacuolar H+ ATPase 68kD subunit 1 http://flybase.net/reports/FBgn0265262.html "FBgn0013354, FBgn0013355, FBgn0020368" protein_coding_gene "0005524=ATP binding, 0046961=proton-transporting ATPase activity, rotational mechanism" "0007035=vacuolar acidification, 0046034=ATP metabolic process, 0015992=proton transport, 0015991=ATP hydrolysis coupled proton transport, 0008593=regulation of Notch signaling pathway, 0071456=cellular response to hypoxia" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0033176=proton-transporting V-type ATPase complex, 0005886=plasma membrane" "ATP6V1A, A subunit, Vacuolar H[+]-ATPase A subunit, vha68-1, CG12403, Vacuolar H[+]-ATPase 68, Vha68, Vha-68-1, vacuolar ATPase subunit A, vha67-1, Vacuolar H[+] ATPase subunit 68-1, Vha68-1, Vha, VhaA, Vacuolar H[+]-ATPase 68kD A subunit" "IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR022878=V-type ATP synthase catalytic alpha chain, IPR024034=ATPase, F1 complex beta subunit/V1 complex, C-terminal, IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005725=ATPase, V1 complex, subunit A" CG12403 16-Dec-15 2015_12 ENSDARG00000034534(atp6v1al) WBGene00013025(vha-13) ENSXETG00000009908(atp6v1a) ENSMUSG00000052459(Atp6v1a) ENSG00000114573(ATP6V1A) FBgn0082613 Su(PDS)P86 Su(PDS)P86 http://flybase.net/reports/FBgn0082613.html gene 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation" FBgn0058311 CG40311 http://flybase.net/reports/FBgn0058311.html FBan0040311 protein_coding_gene 16-Dec-15 2015_12 FBgn0267149 CR45589 http://flybase.net/reports/FBgn0267149.html non_protein_coding_gene lincRNA.766 CR45589 16-Dec-15 2015_12 FBgn0050118 CG30118 http://flybase.net/reports/FBgn0050118.html "FBgn0034347, FBgn0034348" protein_coding_gene "CG5544, CG16859" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR023577=CYTH-like domain" CG30118 16-Dec-15 2015_12 WBGene00021078(W08A12.1) FBgn0060775 l(3)S060914 lethal (3) S060914 http://flybase.net/reports/FBgn0060775.html gene 0609/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267655 CR45993 http://flybase.net/reports/FBgn0267655.html non_protein_coding_gene CR45993 16-Dec-15 2015_12 FBgn0067043 U4 U4 http://flybase.net/reports/FBgn0067043.html gene 16-Dec-15 2015_12 "visible,lethal,partially lethal - majority die" "chaeta,eye" FBgn0038613 Vha100-4 Vacuolar H+ ATPase 100kD subunit 4 http://flybase.net/reports/FBgn0038613.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "CG7678, Vacuolar H[+] ATPase subunit 100-4, vha100-4" "IPR002490=V-type ATPase, V0 complex, 116kDa subunit family, IPR026028=ATPase, V0 complex, subunit 116kDa, eukaryotic" CG7678 16-Dec-15 2015_12 "YOR270C(VPH1),YMR054W(STV1)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0001051 Fs(3)Hub Female sterile (3) Huba http://flybase.net/reports/FBgn0001051.html gene "0040016=embryonic cleavage, 0007344=pronuclear fusion" "Hub, Fs(3)Sz12, Fs(3)Huba" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "female pronucleus | maternal effect,cleavage stage embryo,maternal effect,male pronucleus | maternal effect" FBgn0038324 CG5038 http://flybase.net/reports/FBgn0038324.html protein_coding_gene 0016262=protein N-acetylglucosaminyltransferase activity 0017122=protein N-acetylglucosaminyltransferase complex "IPR013618=Domain of unknown function DUF1736, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG5038 16-Dec-15 2015_12 ENSDARG00000020447(tmtc4) WBGene00018175(F38B6.6) ENSXETG00000020677(TMTC4) ENSMUSG00000041594(Tmtc4) ENSG00000125247(TMTC4) FBgn0061137 l(3)S000903 lethal (3) S000903 http://flybase.net/reports/FBgn0061137.html gene 3-Sep 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0086916 snky sneaky http://flybase.net/reports/FBgn0086916.html "FBgn0011714, FBgn0013665, FBgn0036347" protein_coding_gene 0008270=zinc ion binding "0035045=sperm plasma membrane disassembly, 0007338=single fertilization, 0035042=fertilization, exchange of chromosomal proteins, 0035041=sperm chromatin decondensation" "0001669=acrosomal vesicle, 0016021=integral component of membrane" "ms(3)snky, ms(3)sneaky, ms(3)ry4, CG11281, ms(3)4" "IPR012858=Dendritic cell-specific transmembrane protein-like, IPR001841=Zinc finger, RING-type" CG11281 16-Dec-15 2015_12 ENSDARG00000056077(dcst1) WBGene00019667(K12B6.2) ENSXETG00000012168(DCST1) ENSMUSG00000042672(Dcst1) ENSG00000163357(DCST1) FBgn0010763 l(3)01859 lethal (3) 01859 http://flybase.net/reports/FBgn0010763.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065823 l(2)SH0364 lethal (2) SH0364 http://flybase.net/reports/FBgn0065823.html gene SH2 0364 16-Dec-15 2015_12 "lethal,recessive" FBgn0260588 2L3186 http://flybase.net/reports/FBgn0260588.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0014318 l(3)ry127 lethal (3) ry127 http://flybase.net/reports/FBgn0014318.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039381 SppL Signal peptide peptidase-like http://flybase.net/reports/FBgn0039381.html FBgn0039382 protein_coding_gene "0042500=aspartic endopeptidase activity, intramembrane cleaving" 0006465=signal peptide processing "0016020=membrane, 0005794=Golgi apparatus, 0016021=integral component of membrane, 0005783=endoplasmic reticulum" "CG5901, SPPL3, sppL, SPP-like protein 3, CG17370, Sppl" "IPR007369=Peptidase A22B, signal peptide peptidase, IPR006639=Presenilin/signal peptide peptidase" CG17370 16-Dec-15 2015_12 ENSDARG00000025220(sppl3) WBGene00007979(imp-1) ENSXETG00000026938(sppl3a) ENSMUSG00000029550(Sppl3) ENSG00000157837(SPPL3) "viable,fertile" FBgn0042625 zaro-4 zaro-4 http://flybase.net/reports/FBgn0042625.html gene 16-Dec-15 2015_12 FBgn0086060 snoRNA:Me28S-U1554 http://flybase.net/reports/FBgn0086060.html snoRNA_gene "CR34689, Me28S-Um1554" CR34689 16-Dec-15 2015_12 FBgn0086362 spn-F spn-F http://flybase.net/reports/FBgn0086362.html "FBgn0039837, FBgn0060468, FBgn0003484" protein_coding_gene "0008569=ATP-dependent microtubule motor activity, minus-end-directed" "0051493=regulation of cytoskeleton organization, 0016325=oocyte microtubule cytoskeleton organization, 0007309=oocyte axis specification, 0007317=regulation of pole plasm oskar mRNA localization, 0008103=oocyte microtubule cytoskeleton polarization, 0008407=chaeta morphogenesis, 0007314=oocyte anterior/posterior axis specification" "l(3)S113003b, CG12114, Spindle-F, Spn-F, spindle F, spindle-F, 1130/03, lethal (3) S113003b" CG12114 16-Dec-15 2015_12 DRSC14475 E 0.94910467 -0.679165847 0.350719155 -2.652246509 0.196422755 0.076141319 FBgn0036194 CG11652 http://flybase.net/reports/FBgn0036194.html protein_coding_gene "0017183=peptidyl-diphthamide biosynthetic process from peptidyl-histidine, 0006909=phagocytosis" 0005737=cytoplasm "Diphthamide biosynthesis-like 1, Dph1" IPR016435=Diphthamide synthesis DPH1/DPH2 CG11652 16-Dec-15 2015_12 ENSDARG00000057973(zgc:110702) YIL103W(DPH1) WBGene00007576(dph-1) ENSMUSG00000078789(Dph1) ENSG00000108963(DPH1) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0000775 fs(1)A1245 female sterile (1) A1245 http://flybase.net/reports/FBgn0000775.html gene fs(1)1246 16-Dec-15 2015_12 "female sterile,recessive,viable,reduced,female sterile germline-dependent" "ovary,dorsal appendage" FBgn0038505 CG17283 http://flybase.net/reports/FBgn0038505.html protein_coding_gene 0004190=aspartic-type endopeptidase activity "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0006508=proteolysis" "IPR001461=Aspartic peptidase, IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain" CG17283 16-Dec-15 2015_12 viable FBgn0024671 l(2)k03117 lethal (2) k03117 http://flybase.net/reports/FBgn0024671.html gene 31/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0261833 CR42765 http://flybase.net/reports/FBgn0261833.html non_protein_coding_gene CG42765 CR42765 16-Dec-15 2015_12 FBgn0058141 CG40141 http://flybase.net/reports/FBgn0058141.html protein_coding_gene 16-Dec-15 2015_12 FBgn0086287 GS2192 http://flybase.net/reports/FBgn0086287.html gene 2192 16-Dec-15 2015_12 FBgn0261402 Ir75b Ionotropic receptor 75b http://flybase.net/reports/FBgn0261402.html "FBgn0036758, FBgn0260864, FBgn0261366" protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0015276=ligand-gated ion channel activity" 0050907=detection of chemical stimulus involved in sensory perception "0016020=membrane, 0016021=integral component of membrane" "CG14586-B, CG42643, DmelIR75b, Ir75b, IR75b, IR75abc, CG14586, ionotropic receptor 75b" "IPR001320=Ionotropic glutamate receptor, IPR030406=Ionotropic receptor 75-related" CG42643 16-Dec-15 2015_12 FBgn0259295 EP-899 http://flybase.net/reports/FBgn0259295.html gene 16-Dec-15 2015_12 visible wing vein FBgn0005188 l(2)S42A lethal of Seto 42A http://flybase.net/reports/FBgn0005188.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "puparium,pupa" FBgn0267747 CR46078 http://flybase.net/reports/FBgn0267747.html non_protein_coding_gene CR46078 16-Dec-15 2015_12 FBgn0036962 CG17122 http://flybase.net/reports/FBgn0036962.html protein_coding_gene CG17122 16-Dec-15 2015_12 ENSDARG00000052133 ENSXETG00000004470(C9orf117) ENSMUSG00000038987(1700019L03Rik) ENSG00000160401(C9orf117) viable DRSC10245 I 1.783136295 0.338456215 0.22987199 0.386180845 -0.37925313 -0.431721181 FBgn0039403 Sld5 Sld5 http://flybase.net/reports/FBgn0039403.html FBgn0046371 protein_coding_gene 0043138=3'-5' DNA helicase activity "1900087=positive regulation of G1/S transition of mitotic cell cycle, 0000278=mitotic cell cycle, 0022008=neurogenesis, 0046331=lateral inhibition" 0000811=GINS complex "CG14549, anon-WO0172774.61" "IPR021151=GINS complex, IPR008591=GINS complex, subunit Sld5" CG14549 16-Dec-15 2015_12 ENSDARG00000016044(zgc:100817) YDR489W(SLD5) WBGene00013768(Y113G7B.24) ENSXETG00000016809(BC084169.1) ENSMUSG00000031546(Gins4) ENSG00000147536(GINS4) "lethal,cell cycle defective,dominant,neuroanatomy defective,viable,visible" "embryonic/larval brain,embryonic/larval neuroblast,ganglion mother cell,chaeta" FBgn0001132 gra gravel http://flybase.net/reports/FBgn0001132.html gene "spc, spiracles" 16-Dec-15 2015_12 visible "wing,eye,ommatidium,wing vein,marginal cell,2nd posterior cell,3rd posterior cell" FBgn0000693 flrdQ flight reduced Q http://flybase.net/reports/FBgn0000693.html gene 16-Dec-15 2015_12 "jumping defective,hypoactive,flight defective" FBgn0039429 CG14238 http://flybase.net/reports/FBgn0039429.html protein_coding_gene IPR019169=Transmembrane protein 26 CG14238 16-Dec-15 2015_12 ENSDARG00000014682 WBGene00022469(Y119C1B.3) ENSMUSG00000060044(Tmem26) ENSG00000196932(TMEM26) "viable,visible" "chaeta,supernumerary" DRSC14732 I -1.114302151 -1.601043976 -0.355736792 -1.106297579 0.051333658 -0.504436911 FBgn0036879 Cpr76Bb Cuticular protein 76Bb http://flybase.net/reports/FBgn0036879.html protein_coding_gene "0008012=structural constituent of adult chitin-based cuticle, 0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr76Bb, CG9290" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG9290 16-Dec-15 2015_12 viable FBgn0060316 l(3)S147410 lethal (3) S147410 http://flybase.net/reports/FBgn0060316.html gene 1474/10 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0260631 c02134 http://flybase.net/reports/FBgn0260631.html gene 16-Dec-15 2015_12 wing FBgn0015926 dah discontinuous actin hexagon http://flybase.net/reports/FBgn0015926.html FBgn0015590 protein_coding_gene 0008270=zinc ion binding "0000915=actomyosin contractile ring assembly, 0007349=cellularization" 0019898=extrinsic component of membrane "Apodystrophin, CG6157, fs(1)dah, Apd, Dah" "IPR011992=EF-hand domain pair, IPR000433=Zinc finger, ZZ-type, IPR015153=EF-hand domain, type 1" CG6157 16-Dec-15 2015_12 "viable,fertile,wild-type,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0263405 CR43451 http://flybase.net/reports/FBgn0263405.html non_protein_coding_gene CR43451 16-Dec-15 2015_12 FBgn0034455 CG11007 http://flybase.net/reports/FBgn0034455.html protein_coding_gene 0045454=cell redox homeostasis "IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG11007 16-Dec-15 2015_12 ENSDARG00000007786(tmx2) WBGene00016446(C35D10.10) ENSXETG00000026417(TEgg063n24.1) ENSMUSG00000050043(Tmx2) ENSG00000213593(TMX2) viable DRSC06023 K -0.120194754 0.511220394 -0.035012019 0.810394297 -1.597080235 -0.264647667 FBgn0016956 tilM touch insensitive larva M http://flybase.net/reports/FBgn0016956.html gene line 310 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0275433 CR46265 http://flybase.net/reports/FBgn0275433.html non_protein_coding_gene CR46265 16-Dec-15 2015_12 FBgn0260938 tay tay bridge http://flybase.net/reports/FBgn0260938.html "FBgn0030702, FBgn0013512" protein_coding_gene "0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0008586=imaginal disc-derived wing vein morphogenesis, 0007633=pattern orientation, 0007628=adult walking behavior" 0005634=nucleus "l(1)13Ff, l(1)XI, dAUTS2, XI, l(1)14Ac, Tay Bridge, CG9056, lethal (1) 14Ac" CG9056 16-Dec-15 2015_12 "ENSDARG00000058232(si:dkey-69h6.1),ENSDARG00000056427,ENSDARG00000020946(LOC100150849),ENSDARG00000069483" "ENSXETG00000023851(FBRSL1),ENSXETG00000003588(AUTS2)" ENSMUSG00000029673(Auts2) "ENSG00000158321(AUTS2),ENSG00000156860(FBRS),ENSG00000112787(FBRSL1)" FBgn0058268 CG40268 http://flybase.net/reports/FBgn0058268.html FBan0040268 protein_coding_gene 16-Dec-15 2015_12 DRSC20994 E -0.388938958 -0.981455222 -3.406913178 -0.798662449 FBgn0065876 l(2)SH0241 lethal (2) SH0241 http://flybase.net/reports/FBgn0065876.html gene l(2)SH2 0241 16-Dec-15 2015_12 "lethal,recessive" FBgn0050463 CG30463 http://flybase.net/reports/FBgn0050463.html "FBgn0034148, FBgn0034149, FBgn0034150" protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity "0006493=protein O-linked glycosylation, 0032504=multicellular organism reproduction" "0005829=cytosol, 0016021=integral component of membrane, 0005794=Golgi apparatus, 0031985=Golgi cisterna" "CG8456, CG8463, dppGalNAcT9, CG15713" "IPR001173=Glycosyltransferase 2-like, IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain" CG30463 16-Dec-15 2015_12 WBGene00001630(gly-5) "lethal,partially lethal - majority die,viable" FBgn0067326 A43 A43 http://flybase.net/reports/FBgn0067326.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0029581 CG3080 http://flybase.net/reports/FBgn0029581.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040922 CG15036 http://flybase.net/reports/FBgn0040922.html protein_coding_gene CG15036 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC17968 I -0.752092515 -2.412091698 -0.473370729 0.215032122 1.042428339 -0.155166299 FBgn0052732 CG32732 http://flybase.net/reports/FBgn0052732.html "FBgn0029921, FBgn0029923" protein_coding_gene 0046331=lateral inhibition "CG12542, CG3042" "IPR001214=SET domain, IPR015353=Rubisco LSMT, substrate-binding domain" CG32732 16-Dec-15 2015_12 ENSDARG00000016513(setd3) WBGene00022173(set-27) ENSXETG00000011436(TEgg034h09.1) ENSMUSG00000056770(Setd3) ENSG00000183576(SETD3) "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0263506 CR43495 http://flybase.net/reports/FBgn0263506.html non_protein_coding_gene CR43495 16-Dec-15 2015_12 FBgn0050407 tRNA:CR30407 transfer RNA:CR30407 http://flybase.net/reports/FBgn0050407.html "FBgn0011873, FBgn0050205, FBgn0060213" tRNA_gene "0033463=GGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:gly:58AB, CR30205, tRNA[Gly][[GGA]], AE002575.trna11-GlyTCC, tRNA:G:TCC:AE002575-b, tRNA:G:58AB, chr2R.trna55-GlyTCC, transfer RNA:gly:58AB, CR30407" CR30407 16-Dec-15 2015_12 FBgn0038431 CG10405 http://flybase.net/reports/FBgn0038431.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP155 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG10405 16-Dec-15 2015_12 "viable,fertile" FBgn0004769 l(3)89Eh lethal (3) 89Eh http://flybase.net/reports/FBgn0004769.html gene 16-Dec-15 2015_12 lethal FBgn0262479 CG43069 http://flybase.net/reports/FBgn0262479.html protein_coding_gene chr2R_14750100_14750772.0 "IPR029071=Ubiquitin-related domain, IPR022617=Rad60/SUMO-like domain, IPR000626=Ubiquitin domain" CG43069 16-Dec-15 2015_12 FBgn0042112 mRpL36 mitochondrial ribosomal protein L36 http://flybase.net/reports/FBgn0042112.html FBgn0063207 protein_coding_gene 0003735=structural constituent of ribosome "0032543=mitochondrial translation, 0006412=translation" 0005762=mitochondrial large ribosomal subunit "CG18767, BcDNA:GM01757" IPR000473=Ribosomal protein L36 CG18767 16-Dec-15 2015_12 ENSG00000171421(MRPL36) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0053689 CG33689 http://flybase.net/reports/FBgn0053689.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33689 16-Dec-15 2015_12 FBgn0001478 l(1)9Ff lethal (1) 9Ff http://flybase.net/reports/FBgn0001478.html gene l(1)G3 16-Dec-15 2015_12 "lethal,recessive" FBgn0263404 CG43450 http://flybase.net/reports/FBgn0263404.html protein_coding_gene CG43450 16-Dec-15 2015_12 FBgn0000677 flrd397 flight reduced 397 http://flybase.net/reports/FBgn0000677.html gene 0007629=flight behavior flrd-397 16-Dec-15 2015_12 "courtship behavior defective,male,flight defective" FBgn0026343 Su(tkv*)3-3 Su(tkv*)3-3 http://flybase.net/reports/FBgn0026343.html gene Su(Tkv*)3-3 16-Dec-15 2015_12 FBgn0263459 snoRNA:2R:9445410 http://flybase.net/reports/FBgn0263459.html snoRNA_gene "snoRNA:2R_9445410, chr2R:9073820..9074020, ncRNA_50" CR43574 16-Dec-15 2015_12 FBgn0266420 Ote Otefin http://flybase.net/reports/FBgn0266420.html "FBgn0003022, FBgn0001173" protein_coding_gene "0008134=transcription factor binding, 0003714=transcription corepressor activity, 0005515=protein binding" "0031468=nuclear envelope reassembly, 0048477=oogenesis, 0048132=female germ-line stem cell asymmetric division, 0030513=positive regulation of BMP signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0030718=germ-line stem cell maintenance" "0031965=nuclear membrane, 0034399=nuclear periphery, 0012505=endomembrane system, 0005637=nuclear inner membrane" "CG5581, ote, hal, haulted, halted, otefin" "IPR003887=LEM domain, IPR011015=LEM/LEM-like domain" CG5581 16-Dec-15 2015_12 embryonic stage -- adult stage " embryonic stage && pupal stage , oogenesis stage , embryonic stage -- adult stage , embryonic stage | early " FBgn0035435 PIG-C "Phosphatidylinositol glycan anchor biosynthesis, class C ortholog (H. sapiens)" http://flybase.net/reports/FBgn0035435.html protein_coding_gene 0017176=phosphatidylinositol N-acetylglucosaminyltransferase activity "0006909=phagocytosis, 0048812=neuron projection morphogenesis, 0042996=regulation of Golgi to plasma membrane protein transport, 0006506=GPI anchor biosynthetic process, 0045313=rhabdomere membrane biogenesis" 0016021=integral component of membrane CG12077 IPR009450=Phosphatidylinositol N-acetylglucosaminyltransferase subunit C CG12077 16-Dec-15 2015_12 ENSDARG00000009113(pigc) YPL076W(GPI2) WBGene00011860(T20D3.8) ENSXETG00000000535(PIGC) ENSMUSG00000026698(Pigc) ENSG00000135845(PIGC) "lethal - all die before end of larval stage,viable" "rhabdomere,somatic clone" DRSC08241 I -1.522508011 -0.33410449 -0.675112907 1.473460836 -0.254619322 -0.108450507 FBgn0061359 CG33671 http://flybase.net/reports/FBgn0061359.html "FBgn0033758, FBgn0033759, FBgn0053009, FBgn0053671, FBtr0087883, FBpp0086996, FBtr0087884" protein_coding_gene "0004496=mevalonate kinase activity, 0005524=ATP binding" "0016310=phosphorylation, 0008299=isoprenoid biosynthetic process" 0005777=peroxisome "MevK, CG16804, CG33009, CG16804b, CG8810, CG33009-ORFB, CG33009ORFB, Dromel_CG33672_FBtr0091651_mORF" "IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR013750=GHMP kinase, C-terminal domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR006206=Mevalonate/galactokinase, IPR006204=GHMP kinase N-terminal domain, IPR006205=Mevalonate kinase" CG33671 16-Dec-15 2015_12 ENSDARG00000004130(zgc:103473) YMR208W(ERG12) WBGene00021534(mvk-1) ENSXETG00000018603(MVK) ENSMUSG00000041939(Mvk) ENSG00000110921(MVK) FBgn0260008 UQCR-11 Ubiquinol-cytochrome c reductase 11 kDa subunit http://flybase.net/reports/FBgn0260008.html "FBgn0066066, FBan0041623, FBgn0085725" protein_coding_gene 0008121=ubiquinol-cytochrome-c reductase activity "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" 0005750=mitochondrial respiratory chain complex III "UCRH, Ubiquinol-cytochrome c oxidoreductase 11 kDa, Ucrh, CG41623, Ubiquinol-cytochrome C reductase complex 11 kDa protein, Ubiquinol-cytochrome c reductase 11 kDa protein" "IPR023184=Ubiquinol-cytochrome C reductase hinge domain, IPR003422=Cytochrome b-c1 complex, subunit 6" CG41623 16-Dec-15 2015_12 ENSDARG00000059128 WBGene00012094(T27E9.2) ENSXETG00000004366(UQCRH) ENSMUSG00000063882(Uqcrh) ENSG00000173660(UQCRH) FBgn0003234 ref(3)V refractory to sigma V http://flybase.net/reports/FBgn0003234.html gene 16-Dec-15 2015_12 FBgn0014901 anon-10Ah anon-10Ah http://flybase.net/reports/FBgn0014901.html gene unnamed 16-Dec-15 2015_12 FBgn0263847 snRNA:LU small nuclear RNA Like U http://flybase.net/reports/FBgn0263847.html snRNA_gene "CR43708, ncRNA_38" CR43708 16-Dec-15 2015_12 FBgn0023155 Su(mg)2-4 Suppressor of modifier of gypsy 2-4 http://flybase.net/reports/FBgn0023155.html gene 16-Dec-15 2015_12 FBgn0060649 l(3)S083603 lethal (3) S083603 http://flybase.net/reports/FBgn0060649.html gene 0836/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003682 ter terraced http://flybase.net/reports/FBgn0003682.html gene 16-Dec-15 2015_12 viable "eye,ommatidium" FBgn0060830 l(3)S050217 lethal (3) S050217 http://flybase.net/reports/FBgn0060830.html gene 0502/17 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0264380 CR43832 http://flybase.net/reports/FBgn0264380.html non_protein_coding_gene CR43832 16-Dec-15 2015_12 FBgn0259852 Su(Ste):CR42421 Su(Ste):CR42421 http://flybase.net/reports/FBgn0259852.html non_protein_coding_gene CR42421 CR42421 16-Dec-15 2015_12 FBgn0044825 R1A1-element\ORF1 ORF1 http://flybase.net/reports/FBgn0044825.html FBgn0044022 transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "R1, R1-element\ORF1" "IPR001878=Zinc finger, CCHC-type" 16-Dec-15 2015_12 FBgn0060430 l(3)S126104 lethal (3) S126104 http://flybase.net/reports/FBgn0060430.html gene 1261/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0035870 Gr66a Gustatory receptor 66a http://flybase.net/reports/FBgn0035870.html protein_coding_gene 0008527=taste receptor activity "0017085=response to insecticide, 0007635=chemosensory behavior, 0031000=response to caffeine, 0050909=sensory perception of taste" "0016021=integral component of membrane, 0030425=dendrite, 0030424=axon" "CG7189, Gr66A, GR66a, GR66A, Gustatory receptor 66C1, GR66C1, Gr66, Gr66C1, gustatory receptor 66a" IPR013604=7TM chemoreceptor CG7189 16-Dec-15 2015_12 viable FBgn0085589 CG41268 http://flybase.net/reports/FBgn0085589.html FBan0041268 protein_coding_gene 16-Dec-15 2015_12 FBgn0028862 dao down and out http://flybase.net/reports/FBgn0028862.html FBgn0044756 protein_coding_gene 0005886=plasma membrane "BG:DS07295.2, anon-WO0140519.126, CG15267" IPR011990=Tetratricopeptide-like helical domain CG15267 16-Dec-15 2015_12 "paralytic,recessive,heat sensitive,neurophysiology defective,viable" dorsal medial muscle FBgn0041726 Rt1a\pol pol http://flybase.net/reports/FBgn0041726.html FBgn0042678 transposable_element_gene "ORF2, pilger\pol, Waldo-B\RTase" "IPR000477=Reverse transcriptase domain, IPR005135=Endonuclease/exonuclease/phosphatase" 16-Dec-15 2015_12 FBgn0025148 ms(2)A8 ms(2)A8 http://flybase.net/reports/FBgn0025148.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0004402 Datp Diadenosine tetraphosphatase http://flybase.net/reports/FBgn0004402.html "FBgn0004226, FBgn0004238" gene 0004081=bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity Ap[[4]]A 16-Dec-15 2015_12 " embryonic stage , adult stage && oogenesis stage " oocyte

FBgn0052373 CG32373 http://flybase.net/reports/FBgn0052373.html FBgn0047069 protein_coding_gene 0005509=calcium ion binding 0008039=synaptic target recognition "CG3237, BcDNA:RE64043" "IPR001881=EGF-like calcium-binding domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR000436=Sushi/SCR/CCP domain, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR026823=Complement Clr-like EGF domain" CG32373 16-Dec-15 2015_12 ENSXETG00000017104() "ENSMUSG00000026580(Selp),ENSMUSG00000026582(Sele)" "viable,fertile" FBgn0013767 Crz Corazonin http://flybase.net/reports/FBgn0013767.html protein_coding_gene "0005184=neuropeptide hormone activity, 0071858=corazonin receptor binding" "0006117=acetaldehyde metabolic process, 0045823=positive regulation of heart contraction, 0007218=neuropeptide signaling pathway, 0071361=cellular response to ethanol, 0048149=behavioral response to ethanol" 0005615=extracellular space "CORZ, preprocorazonin, crz, Drm-COR, cor, CG3302, Cora, Dm-Crz, corazonin, CRZ, COR" IPR020190=Procorazonin CG3302 16-Dec-15 2015_12 embryonic stage | stage 17 EW3 neuron

"viable,chemical resistant" FBgn0039795 Spn100A Serpin 100A http://flybase.net/reports/FBgn0039795.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "Spn100, CG1342" "IPR000215=Serpin family, IPR023796=Serpin domain" CG1342 16-Dec-15 2015_12 viable FBgn0039302 Nup358 Nucleoporin 358kD http://flybase.net/reports/FBgn0039302.html protein_coding_gene "0008536=Ran GTPase binding, 0008270=zinc ion binding" "0007184=SMAD protein import into nucleus, 0006607=NLS-bearing protein import into nucleus, 0006606=protein import into nucleus" "0005875=microtubule associated complex, 0005643=nuclear pore, 0005811=lipid particle" "CG11856, Nucleoporin 358, NUP358, Nup358, Q9VBU7_DROME, RanBP2, nup358" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR011990=Tetratricopeptide-like helical domain, IPR001876=Zinc finger, RanBP2-type, IPR000156=Ran binding domain, IPR013026=Tetratricopeptide repeat-containing domain" CG11856 16-Dec-15 2015_12 ENSXETG00000016006() "ENSG00000153201(RANBP2),ENSG00000196862(RGPD4),ENSG00000153165(RGPD3),ENSG00000183054(RGPD6),ENSG00000015568(RGPD5),ENSG00000169629(RGPD8),ENSG00000185304(RGPD2),ENSG00000187627(RGPD1)" "visible,partially lethal - majority die,some die during pupal stage" "tormogen cell,mesothoracic tergum" DRSC14410 IE 2.253897358 -0.390207146 4.362557625 0.668485866 -0.346054226 1.22586238 FBgn0014943 anon-98Dd anon-98Dd http://flybase.net/reports/FBgn0014943.html gene unnamed 16-Dec-15 2015_12 FBgn0015785 Pla Plane http://flybase.net/reports/FBgn0015785.html gene 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0005424 l(1)adl13 lethal (1) adl13 http://flybase.net/reports/FBgn0005424.html gene l(1)adl-13 16-Dec-15 2015_12 "short lived,heat sensitive,lethal,phototaxis defective,locomotor behavior defective,behavior defective,some die during immature adult stage,recessive" FBgn0002894 mus208 mutagen-sensitive 208 http://flybase.net/reports/FBgn0002894.html gene 16-Dec-15 2015_12 "chemical sensitive,viable,fertile,maternal effect" FBgn0030318 rho-4 rhomboid-4 http://flybase.net/reports/FBgn0030318.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity, 0005509=calcium ion binding" 0006508=proteolysis "0016021=integral component of membrane, 0005886=plasma membrane" "Rhomboid 4, Rho-4, Rhomboid-4, Rho-related [10C6], rho 4, CG1697, rho4" "IPR017213=Peptidase S54, rhomboid, metazoan, IPR002610=Peptidase S54, rhomboid, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR022764=Peptidase S54, rhomboid domain, IPR002048=EF-hand domain" CG1697 16-Dec-15 2015_12 "viable,fertile" "wing,wing vein,ectopic" FBgn0019889 anon-42Ea anon-42Ea http://flybase.net/reports/FBgn0019889.html gene unnamed 16-Dec-15 2015_12 visible eye FBgn0003209 raw raw http://flybase.net/reports/FBgn0003209.html "FBgn0010627, FBgn0015377, FBgn0022218, FBgn0032063, FBgn0032064" protein_coding_gene "0035297=regulation of Malpighian tubule diameter, 0002009=morphogenesis of an epithelium, 0048567=ectodermal digestive tract morphogenesis, 0007390=germ-band shortening, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0007435=salivary gland morphogenesis, 0046329=negative regulation of JNK cascade, 0008360=regulation of cell shape, 0008406=gonad development, 0007422=peripheral nervous system development, 0008104=protein localization, 0007391=dorsal closure, 0007443=Malpighian tubule morphogenesis, 0007442=hindgut morphogenesis, 0046328=regulation of JNK cascade, 0007417=central nervous system development, 0035262=gonad morphogenesis, 0007394=dorsal closure, elongation of leading edge cells" 0005886=plasma membrane "l(2)06825, cyrano, CG9321, l(2)k03514, cyr, ensh, ensheathment defects, CG12437" CG12437 16-Dec-15 2015_12 " embryonic stage | stage 7 , embryonic stage | stage >=13 , adult stage | female , embryonic stage | stage 8-12 , adult stage | male , embryonic stage | 12-16hr , embryonic stage | stage 7-12 , embryonic stage | stage 17 , embryonic stage " " dorsal fold

, embryonic/larval midgut

, ventral neurogenic region

, embryonic central nervous system

, ventral furrow

, midgut primordium

, cephalic furrow

, midgut constriction 2

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,fully,rescuable maternal effect,visible,partially lethal - majority die,some die during pupal stage" "dorsal closure embryo,presumptive embryonic/larval peripheral nervous system,neuron,extended germ band embryo,axon,embryonic/first instar larval cuticle,ventral,dorsal,gonad,gonadal sheath proper primordium,germline cell,male germline cell,embryonic Malpighian tubule,embryonic/larval digestive system,embryonic epidermis,embryonic head,Malpighian tubule,presumptive embryonic/larval central nervous system,embryonic/larval midgut,midgut constriction,embryonic/larval salivary gland,embryonic/larval hindgut,denticle,dorsal hair,trichogen cell,mesothoracic tergum" DRSC03599 IE -0.63442445 -5.922431427 -0.558955585 -3.723967213 0.835753407 -0.938173639 FBgn0051642 CG31642 http://flybase.net/reports/FBgn0051642.html FBgn0031780 protein_coding_gene 0008270=zinc ion binding CG5981 "IPR000433=Zinc finger, ZZ-type, IPR015880=Zinc finger, C2H2-like" CG31642 16-Dec-15 2015_12 WBGene00022785(ZK652.6) FBgn0028926 NC2ë_ Negative Cofactor 2ë_ http://flybase.net/reports/FBgn0028926.html protein_coding_gene "0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0043565=sequence-specific DNA binding, 0004402=histone acetyltransferase activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" "0042766=nucleosome mobilization, 0016573=histone acetylation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0017055=negative regulation of RNA polymerase II transcriptional preinitiation complex assembly, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006338=chromatin remodeling" "0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0017054=negative cofactor 2 complex, 0005634=nucleus" "NC2beta, NC2 beta, Dr1, dNC2, CG4185, dDr1, BG:DS00929.3, Nc2b" "IPR009072=Histone-fold, IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain" CG4185 16-Dec-15 2015_12 ENSDARG00000059752(dr1) YDR397C(NCB2) WBGene00001092(dro-1) ENSXETG00000022989(dr1) ENSMUSG00000029265(Dr1) ENSG00000117505(DR1) viable FBgn0019873 anon-92Ef anon-92Ef http://flybase.net/reports/FBgn0019873.html gene unnamed 16-Dec-15 2015_12 FBgn0010333 Rac1 Rac1 http://flybase.net/reports/FBgn0010333.html FBgn0014012 protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0032794=GTPase activating protein binding, 0019901=protein kinase binding, 0005525=GTP binding" "0007015=actin filament organization, 0050807=regulation of synapse organization, 0001954=positive regulation of cell-matrix adhesion, 0007411=axon guidance, 0016335=morphogenesis of larval imaginal disc epithelium, 0007298=border follicle cell migration, 0000902=cell morphogenesis, 0035011=melanotic encapsulation of foreign target, 0035320=imaginal disc-derived wing hair site selection, 0032147=activation of protein kinase activity, 0048747=muscle fiber development, 0007426=tracheal outgrowth, open tracheal system, 0048615=embryonic anterior midgut (ectodermal) morphogenesis, 0007394=dorsal closure, elongation of leading edge cells, 0031532=actin cytoskeleton reorganization, 0007422=peripheral nervous system development, 0045216=cell-cell junction organization, 0016203=muscle attachment, 0016358=dendrite development, 0048813=dendrite morphogenesis, 0051963=regulation of synapse assembly, 0008078=mesodermal cell migration, 0051450=myoblast proliferation, 0046843=dorsal appendage formation, 0034334=adherens junction maintenance, 0007413=axonal fasciculation, 0035010=encapsulation of foreign target, 0007409=axonogenesis, 0048814=regulation of dendrite morphogenesis, 0030866=cortical actin cytoskeleton organization, 0006909=phagocytosis, 0045773=positive regulation of axon extension, 0007419=ventral cord development, 0045610=regulation of hemocyte differentiation, 0007391=dorsal closure, 0090303=positive regulation of wound healing, 0051726=regulation of cell cycle, 0035212=cell competition in a multicellular organism, 0008347=glial cell migration, 0030707=ovarian follicle cell development, 0008258=head involution, 0007254=JNK cascade, 0007516=hemocyte development, 0007424=open tracheal system development, 0031175=neuron projection development, 0002433=immune response-regulating cell surface receptor signaling pathway involved in phagocytosis, 0042052=rhabdomere development, 0008283=cell proliferation, 0007395=dorsal closure, spreading of leading edge cells, 0035099=hemocyte migration, 0046664=dorsal closure, amnioserosa morphology change, 0006974=cellular response to DNA damage stimulus, 0030036=actin cytoskeleton organization, 0008045=motor neuron axon guidance, 0042067=establishment of ommatidial planar polarity, 0048675=axon extension, 0007520=myoblast fusion, 0050770=regulation of axonogenesis, 0007390=germ-band shortening, 0097206=nephrocyte filtration, 0010593=negative regulation of lamellipodium assembly, 0051017=actin filament bundle assembly, 0007264=small GTPase mediated signal transduction, 0030032=lamellipodium assembly, 0050975=sensory perception of touch, 0051491=positive regulation of filopodium assembly, 0007164=establishment of tissue polarity, 0071907=determination of digestive tract left/right asymmetry, 1902669=positive regulation of axon guidance, 0007435=salivary gland morphogenesis, 0016199=axon midline choice point recognition, 0007017=microtubule-based process" "0001726=ruffle, 0031941=filamentous actin, 0005886=plasma membrane, 0005737=cytoplasm, 0019897=extrinsic component of plasma membrane, 0016028=rhabdomere" "RacA, dRac1, Rac GTPase, rac, dRac, DRac, DRac1, GTPase Rac1, P40792, Rac, rac1, D-Rac, DRacA, CG2248, DracA, Drac, Dm Rac1, DmRAC, D-Rac1, 2248, Dmrac1, Drac1, DmRAC1, Rac3, Rac-1, D-Rac 1, Drac1a, RAC1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain" CG2248 16-Dec-15 2015_12 "ENSDARG00000030947,ENSDARG00000002951,ENSDARG00000020795(zgc:175209),ENSDARG00000040651(rac3)" "WBGene00000424(ced-10),WBGene00004287(rac-2)" "ENSXETG00000027593(Rac1),ENSXETG00000004629(BC087999.1)" "ENSMUSG00000018012(Rac3),ENSMUSG00000001847(Rac1)" "ENSG00000169750(RAC3),ENSG00000128340(RAC2),ENSG00000136238(RAC1)" " embryonic stage , embryonic stage | stage 10-12 , embryonic stage | blastoderm , embryonic stage -- adult stage " "

ubiquitous , somatic mesoderm

, embryonic/larval digestive system

, embryonic central nervous system

" "lethal,visible,planar polarity defective,wild-type,neuroanatomy defective,somatic clone,dominant,immune response defective,male semi-sterile,cell shape defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable,developmental rate defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,oxidative stress response defective,starvation stress response defective,stress response defective,touch sensitivity defective,cell death defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective,size defective,cell polarity defective,female,heat sensitive,cell migration defective,chemical sensitive,chemical resistant" "embryonic/larval pericardial cell,dorsal closure embryo,embryonic/first instar larval cuticle,border follicle cell,ommatidium,eye,interommatidial bristle,photoreceptor,pigment cell,photoreceptor cell,adult mushroom body,dendritic arborizing neuron,dorsal multidendritic neuron ddaC,peripheral glial cell,somatic clone,LNv neuron,ventral adult lateral neuron & commissure,axon & dorsal cluster neuron | somatic clone,presumptive embryonic salivary gland,lobe system of adult mushroom body,polar follicle cell,abdominal intersegmental nerve,axon,myoblast,photoreceptor cell & axonGMR.PF,primordium of embryonic/larval spiracle,macrophage,embryonic myoblast,dorsal,wing disc,wing,microchaeta & wingptc-559.1,anterior compartment,lamina,medulla,indirect flight muscle | larval stage,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,adult muscle precursor cell,A1-7 lateral longitudinal muscle 1,embryonic hemocyte,ventral nerve cord | embryonic stage,dorsal appendage,nurse follicle cell,eye disc,motor neuron,intersegmental nerve,ventral midline,medial longitudinal fascicle,abdominal segmental nerve,longitudinal connective,embryonic/larval midgut | embryonic stage,rhabdomereunspecified,rhabdomere & microvillusunspecified,rhabdomere & actin filamentunspecified,embryonic dorsal epidermis,hemocyte,lamellocyte,crystal cell,amnioserosa,embryonic epidermis,embryonic leading edge cell & actin filamenten-e16E,lamellipodiumen-e16E,embryonic segment,eye photoreceptor cell,presumptive embryonic/larval tracheal system,tracheal branch primordium,dorsal group branch precursor,dorsal trunk primordium,axon & dorsal cluster neuronato.3.6,aCC neuron,RP2 motor neuron,mesothoracic intersegmental nerve,metathoracic intersegmental nerve,prothoracic intersegmental nerve,dendritic spine & lobular plate tangential neuronDB331,neurite,giant axon,dendrite,rhabdomereGMR.PU,retina,embryonic/larval hindgut,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3,egg chamber,follicle cell,multidendritic neuron & dendrite | supernumerary477,multidendritic neuron & dendrite477,filopodium & dendrite109(2)80,macrochaeta,wing vein,sensillum campaniformium,melanotic mass,class I dendritic arborizing neuron,dendrite221,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage,dorsal cluster neuron | larval stage,filamentous actinppk.PG,posterior,embryonic/larval dorsal trunk | embryonic stage,embryonic/larval dorsal branch | embryonic stage,pCC neuron,dMP2 neuron,vMP2 neuron,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,embryonic/larval somatic muscle,midgut primordium,hindgut proper primordium,embryonic/larval trachea,actin filament & border follicle cell | somatic clone,germ band,dendrite | dorsal | embryonic stage60,VUM neuron,ventral nerve cord commissure,ventral nerve cord,embryonic/larval neuron,embryonic anterior Malpighian tubule,antennal lobe,antennal commissure,denticle,ectopic,longitudinal visceral muscle primordium,mesoderm | embryonic stage 8,germline cell | embryonic stage,anterior embryonic/larval midgut,muscle fiber | embryonic stage" DRSC08688 IE -0.532492871 -4.401186956 -0.816858829 -1.593446606 -0.517344632 -0.985812725 FBgn0002122 l(2)H lethal (2) Humphrey http://flybase.net/reports/FBgn0002122.html gene 16-Dec-15 2015_12 "sterile,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262378 mir-317 mir-317 stem loop http://flybase.net/reports/FBgn0262378.html "FBgn0067687, FBgn0262193" miRNA_gene "0002121=inter-male aggressive behavior, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 0048854=brain morphogenesis" "Mir-317, mir-317, dme-mir-317, 317, miR-317, CR33621, CR42900" CR42900 16-Dec-15 2015_12 FBgn0065136 l(3)SH116 lethal (3) SH116 http://flybase.net/reports/FBgn0065136.html gene l(2)SH3 116 16-Dec-15 2015_12 "lethal,recessive" FBgn0040747 CG12853 http://flybase.net/reports/FBgn0040747.html FBgn0045180 protein_coding_gene "NEST:bs26d12, bs26d12.y1" CG12853 16-Dec-15 2015_12 viable FBgn0010431 mtrm matrimony http://flybase.net/reports/FBgn0010431.html protein_coding_gene "0051445=regulation of meiotic cell cycle, 0016321=female meiosis chromosome segregation, 0032837=distributive segregation" 0005634=nucleus "D52, anon-D52, anonD52, CG18543" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG18543 16-Dec-15 2015_12 "female fertile,meiotic cell cycle defective,dominant,female sterile,recessive,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte nucleus,oocyte & nuclear chromosome,cystoblast,karyosome,meiotic spindle66C-T2-10)" FBgn0060715 l(3)S069805 lethal (3) S069805 http://flybase.net/reports/FBgn0060715.html gene 0698/05 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085359 CG34330 http://flybase.net/reports/FBgn0085359.html protein_coding_gene 0022008=neurogenesis CG33254 CG34330 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,mesothoracic tergum" FBgn0040555 CG14371 http://flybase.net/reports/FBgn0040555.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005450 l(1)v227 lethal (1) v227 http://flybase.net/reports/FBgn0005450.html gene l(1)227 16-Dec-15 2015_12 FBgn0069922 CG41129 http://flybase.net/reports/FBgn0069922.html FBan0041129 protein_coding_gene 16-Dec-15 2015_12 FBgn0003619 Su(var)2-57 Suppressor of variegation 2-57 http://flybase.net/reports/FBgn0003619.html gene 16-Dec-15 2015_12 FBgn0016876 l(2)39DEa lethal (2) 39DEa http://flybase.net/reports/FBgn0016876.html gene A447 16-Dec-15 2015_12 lethal FBgn0037329 POLDIP2 "Polymerase (DNA-directed), delta interacting protein 2" http://flybase.net/reports/FBgn0037329.html protein_coding_gene 0003677=DNA binding CG12162 "IPR011722=Hemimethylated DNA-binding domain, IPR007474=ApaG domain" CG12162 16-Dec-15 2015_12 ENSDARG00000055632(poldip2) WBGene00022787(tag-307) ENSXETG00000023792() ENSMUSG00000001100(Poldip2) ENSG00000004142 "viable,fertile" FBgn0001243 hypoC hypoactive C http://flybase.net/reports/FBgn0001243.html gene 0007629=flight behavior 16-Dec-15 2015_12 "hypoactive,optomotor response defective,courtship behavior defective,female,jumping defective,locomotor behavior defective,flight defective" embryonic/larval heart FBgn0038110 CG8031 http://flybase.net/reports/FBgn0038110.html protein_coding_gene dMEMO IPR002737=MEMO1 family CG8031 16-Dec-15 2015_12 ENSDARG00000010823(memo1) YJR008W() WBGene00016500(tag-253) ENSXETG00000008547(TGas016p14.1) ENSMUSG00000058704(Memo1) ENSG00000162959(MEMO1) viable DRSC16364 K -1.171711852 -0.004898056 -0.218406513 0.423208207 -1.981113688 -0.226154002 FBgn0028236 l(3)S003006 lethal (3) S003006 http://flybase.net/reports/FBgn0028236.html gene "30/6, 0030/06" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0264259 Roc1a::Roc1b http://flybase.net/reports/FBgn0264259.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0037970 GC2 Glutamate Carrier 2 http://flybase.net/reports/FBgn0037970.html protein_coding_gene "0022857=transmembrane transporter activity, 0005314=high-affinity glutamate transmembrane transporter activity" "0055085=transmembrane transport, 0015813=L-glutamate transport, 0006839=mitochondrial transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "CG12201, DmGC2" "IPR023395=Mitochondrial carrier domain, IPR002067=Mitochondrial carrier protein, IPR018108=Mitochondrial substrate/solute carrier" CG12201 16-Dec-15 2015_12 "ENSDARG00000020718(LOC571044),ENSDARG00000058336,ENSDARG00000013749(zgc:92113),ENSDARG00000020893(slc25a22),ENSDARG00000070717(im:7143718)" WBGene00008979(F20D1.9) "ENSXETG00000000870(SLC25A18),ENSXETG00000023334(SLC25A22),ENSXETG00000015362(slc25a22)" "ENSMUSG00000019082(Slc25a22),ENSMUSG00000004902(Slc25a18)" "ENSG00000177542(SLC25A22),ENSG00000182902(SLC25A18)" viable FBgn0262530 CG43084 http://flybase.net/reports/FBgn0262530.html protein_coding_gene CG43084 16-Dec-15 2015_12 FBgn0034588 CG9394 http://flybase.net/reports/FBgn0034588.html FBgn0027723 protein_coding_gene "2001070=starch binding, 0008081=phosphoric diester hydrolase activity" 0006629=lipid metabolic process anon-EST:Posey227 "IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR013784=Carbohydrate-binding-like fold, IPR002044=Carbohydrate binding module family 20, IPR013783=Immunoglobulin-like fold, IPR030395=Glycerophosphodiester phosphodiesterase domain" CG9394 16-Dec-15 2015_12 viable DRSC04550 E -0.65647632 0.922836519 1.663316794 0.196380732 -0.807330223 0.767993432 FBgn0020901 Su(osk)B11 Suppressor of oskar B11 http://flybase.net/reports/FBgn0020901.html gene B11 16-Dec-15 2015_12 FBgn0037666 CR16735 http://flybase.net/reports/FBgn0037666.html pseudogene_attribute CG16735 CR16735 16-Dec-15 2015_12 "viable,fertile" FBgn0262866 S6kII Ribosomal protein S6 kinase II http://flybase.net/reports/FBgn0262866.html "FBgn0011285, FBgn0086241" protein_coding_gene "0000287=magnesium ion binding, 0004674=protein serine/threonine kinase activity, 0005515=protein binding, 0004711=ribosomal protein S6 kinase activity, 0005524=ATP binding" "0045475=locomotor rhythm, 0035106=operant conditioning, 0008306=associative learning, 0007474=imaginal disc-derived wing vein specification, 0046580=negative regulation of Ras protein signal transduction, 0006468=protein phosphorylation, 0008340=determination of adult lifespan, 0007528=neuromuscular junction development, 0050941=negative regulation of pigment cell differentiation, 0042308=negative regulation of protein import into nucleus, 0042683=negative regulation of compound eye cone cell fate specification, 0046533=negative regulation of photoreceptor cell differentiation" 0031594=neuromuscular junction "p90 ribosomal S6 kinase, rsk, ign, S6 kinase II, rsk2, CG17596, S6KII, RSK, Rsk, RPS6-protein kinase-II, ignorant, dRSK, ribosomal-S6-kinase, Ribosomal-S6-kinase" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR016239=Ribosomal protein S6 kinase II" CG17596 16-Dec-15 2015_12 "ENSDARG00000033437(rps6ka1),ENSDARG00000028469,ENSDARG00000035556(rps6ka3a),ENSDARG00000037574(rps6kal),ENSDARG00000057927(rps6ka3b)" WBGene00011352(rskn-1) "ENSXETG00000012289(RPS6KA1),ENSXETG00000014506(RPS6KA6),ENSXETG00000025994(RPS6KA2)" "ENSMUSG00000003644(Rps6ka1),ENSMUSG00000031309(Rps6ka3),ENSMUSG00000023809(Rps6ka2),ENSMUSG00000025665(Rps6ka6)" "ENSG00000071242(RPS6KA2),ENSG00000177189(RPS6KA3),ENSG00000117676(RPS6KA1),ENSG00000072133(RPS6KA6)" DRSC20645 I 2.478065299 0.828545961 0.413457051 0.311762505 0.388344985 -0.031134091 FBgn0025745 l(3)tb lethal (3) tumorous brain http://flybase.net/reports/FBgn0025745.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "optic lobe,wing disc" FBgn0032290 CG6443 http://flybase.net/reports/FBgn0032290.html protein_coding_gene "IPR027799=Replication termination factor 2, RING-finger, IPR006735=Protein of unknown function DUF602" CG6443 16-Dec-15 2015_12 ENSDARG00000040607(zgc:55448) WBGene00007217(C01A2.5) ENSXETG00000012028(Q6NVS6_XENTR) ENSMUSG00000027502(2410001C21Rik) ENSG00000022277(C20orf43) "viable,visible" mesothoracic tergum DRSC02958 EK 0.472332685 0.740737273 1.593101841 0.994644068 1.786021454 0.77370707 FBgn0060453 l(3)S119601b lethal (3) S119601b http://flybase.net/reports/FBgn0060453.html gene 1196/01 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0085636 CG41373 http://flybase.net/reports/FBgn0085636.html FBan0041373 protein_coding_gene 16-Dec-15 2015_12 FBgn0267222 CR45662 http://flybase.net/reports/FBgn0267222.html non_protein_coding_gene CR45662 16-Dec-15 2015_12 FBgn0070028 BG00372 BG00372 http://flybase.net/reports/FBgn0070028.html gene 0002121=inter-male aggressive behavior 16-Dec-15 2015_12 "stress response defective,behavior defective,recessive" FBgn0278599 CR46269 http://flybase.net/reports/FBgn0278599.html non_protein_coding_gene CR46269 16-Dec-15 2015_12 FBgn0264415 FCE-H http://flybase.net/reports/FBgn0264415.html gene 16-Dec-15 2015_12 "egg chamber,somatic clone" FBgn0030462 CG15742 http://flybase.net/reports/FBgn0030462.html protein_coding_gene CG15742 16-Dec-15 2015_12 viable FBgn0030586 CG12539 http://flybase.net/reports/FBgn0030586.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity, 0004344=glucose dehydrogenase activity" "0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process" Dm GMCiota2 "IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR012132=Glucose-methanol-choline oxidoreductase" CG12539 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) viable FBgn0015996 l(3)03884 lethal (3) 03884 http://flybase.net/reports/FBgn0015996.html gene "l(3)3884, unnamed" 16-Dec-15 2015_12 "lethal,recessive" FBgn0011652 Mads-4 Mads-4 http://flybase.net/reports/FBgn0011652.html gene 16-Dec-15 2015_12 FBgn0021959 l(2)k10209 lethal (2) k10209 http://flybase.net/reports/FBgn0021959.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive,visible" "leg,metathoracic femur" FBgn0036170 CG11714 http://flybase.net/reports/FBgn0036170.html FBgn0053047 protein_coding_gene CG33047 "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG11714 16-Dec-15 2015_12 "viable,fertile" FBgn0016765 anon-17Cb anon-17Cb http://flybase.net/reports/FBgn0016765.html gene "Transcription unit C2, C2" 16-Dec-15 2015_12 " embryonic stage | early , adult stage | female " FBgn0263520 mir-4945 mir-4945 stem loop http://flybase.net/reports/FBgn0263520.html miRNA_gene "CR43505, dme-mir-4945" CR43505 16-Dec-15 2015_12 FBgn0002879 mus102 mutagen-sensitive 102 http://flybase.net/reports/FBgn0002879.html gene "mus-102, mus 102, mus(1)102" 16-Dec-15 2015_12 "chemical sensitive,recessive,female fertile,reduced,meiotic cell cycle defective,mitotic cell cycle defective,radiation sensitive" mitosis & nuclear chromosome FBgn0004020 wobB wobbly B http://flybase.net/reports/FBgn0004020.html gene 16-Dec-15 2015_12 uncoordinated FBgn0051788 CG31788 http://flybase.net/reports/FBgn0051788.html protein_coding_gene CG31788 16-Dec-15 2015_12 viable DRSC01630 IE 2.673435216 0.176133719 -2.295411984 0.04372888 -0.192691856 -0.417913717 FBgn0034415 CG15116 http://flybase.net/reports/FBgn0034415.html protein_coding_gene 0004602=glutathione peroxidase activity "0006979=response to oxidative stress, 0055114=oxidation-reduction process, 0032504=multicellular organism reproduction" 0005615=extracellular space GPx-like "IPR000889=Glutathione peroxidase, IPR012336=Thioredoxin-like fold" CG15116 16-Dec-15 2015_12 "ENSDARG00000013302(zgc:56280),ENSDARG00000020415" "YBR244W(GPX2),YIR037W(HYR1),YKL026C(GPX1)" ENSXETG00000007753() "viable,visible" trichogen cell FBgn0014847 Egfr::tor Egfr::tor http://flybase.net/reports/FBgn0014847.html engineered_fusion_gene "unnamed, EGFR" 16-Dec-15 2015_12 "visible,lethal,heat sensitive,decreased cell death,increased cell size,cell death defective,somatic clone,neuroanatomy defective" "eye,mystery cell,primary pigment cell,cone cell,photoreceptor cell R7,ganglionic branch 1 | embryonic stage,eye disc,photoreceptor cell,morphogenetic furrow,photoreceptor,cell autonomous,ectopic,somatic clone,cell non-autonomous,ommatidial precursor cluster,wing,embryonic segment,supernumerary,dorsocentral bristle,enterocyte,adult gut,midgut,embryonic/larval brain | third instar larval stage,embryonic/larval neuroblast,ectopic | third instar larval stage" FBgn0041581 AttB Attacin-B http://flybase.net/reports/FBgn0041581.html "FBgn0033959, FBgn0041580" protein_coding_gene "0006952=defense response, 0006959=humoral immune response, 0050830=defense response to Gram-positive bacterium, 0042742=defense response to bacterium, 0019731=antibacterial humoral response" "0005615=extracellular space, 0005576=extracellular region" "Attacin B, Attacin B1, Attb, AttB2, Attacin, att, CG18372, AttacinB, attB, Att, AttBn, AttB1, Attackin, attacin, att B1, attacinB, Att B, attacin B, Attacin-B precursor" "IPR005520=Attacin, N-terminal, IPR005521=Attacin, C-terminal" CG18372 16-Dec-15 2015_12 viable FBgn0001159 gustB gustatory-defective B http://flybase.net/reports/FBgn0001159.html gene "gust[x5], gusF" 16-Dec-15 2015_12 "taste perception defective,recessive" labellar taste bristle FBgn0052639 CG32639 http://flybase.net/reports/FBgn0052639.html protein_coding_gene CG32639 16-Dec-15 2015_12 viable DRSC18972 E -0.405936113 0.428500835 -1.517566218 0.802459952 0.813863658 -0.526476637 FBgn0267734 CR46065 http://flybase.net/reports/FBgn0267734.html non_protein_coding_gene Mgn00290 CR46065 16-Dec-15 2015_12 FBgn0085433 CG34404 http://flybase.net/reports/FBgn0085433.html "FBgn0027349, FBgn0038329, FBgn0038328" protein_coding_gene "unnamed, CG6156, anon-FF, CG18496" "IPR019536=Usher syndrome type-1C protein-binding protein 1, PDZ domain" CG34404 16-Dec-15 2015_12 ENSDARG00000039195 ENSXETG00000021515(MCC) ENSMUSG00000071856 ENSG00000171444(MCC) viable FBgn0065743 l(2)SH0521 lethal (2) SH0521 http://flybase.net/reports/FBgn0065743.html gene l(2)SH2 0521 16-Dec-15 2015_12 "lethal,recessive" FBgn0083998 CG41431 http://flybase.net/reports/FBgn0083998.html FBan0041431 protein_coding_gene 16-Dec-15 2015_12 FBgn0020285 l(3)06266 lethal (3) 06266 http://flybase.net/reports/FBgn0020285.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0034647 pirk poor Imd response upon knock-in http://flybase.net/reports/FBgn0034647.html FBgn0062875 protein_coding_gene "0005102=receptor binding, 0005515=protein binding" "0045824=negative regulation of innate immune response, 0061060=negative regulation of peptidoglycan recognition protein signaling pathway, 0009609=response to symbiotic bacterium, 0050777=negative regulation of immune response" "BcDNA:SD16010, rudra, Pims, pims, PIRK, PGRP-LC-interacting inhibitor of Imd signaling, CG15678, Pirk, Rudra" CG15678 16-Dec-15 2015_12 "immune response defective,viable,fertile,short lived" FBgn0035282 CNMa CNMamide http://flybase.net/reports/FBgn0035282.html protein_coding_gene 0005184=neuropeptide hormone activity 0007186=G-protein coupled receptor signaling pathway 0005615=extracellular space CG13936 CG13936 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267691 CR46027 http://flybase.net/reports/FBgn0267691.html pseudogene_attribute mdcds_23070 CR46027 16-Dec-15 2015_12 FBgn0010520 Bka Bekka http://flybase.net/reports/FBgn0010520.html "FBgn0032155, FBgn0063059" protein_coding_gene "0048812=neuron projection morphogenesis, 0009267=cellular response to starvation, 0048096=chromatin-mediated maintenance of transcription" "0005634=nucleus, 0032040=small-subunit processome" "BcDNA:RE14949, l(2)02695, mip, missing imaginal precursors, CG4539" "IPR006984=rRNA-processing protein Fcf1/Utp23, IPR002716=PIN domain, IPR029060=PIN domain-like" CG4539 16-Dec-15 2015_12 ENSDARG00000041373 YDR339C(FCF1) WBGene00009266(F30A10.9) ENSXETG00000027288(BC075594.1) ENSMUSG00000021243(Fcf1) ENSG00000119616(FCF1) "lethal,recessive,viable" FBgn0065874 l(2)SH0246 lethal (2) SH0246 http://flybase.net/reports/FBgn0065874.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051802 CG31802 http://flybase.net/reports/FBgn0051802.html "FBgn0032676, FBgn0063716" protein_coding_gene 0005509=calcium ion binding "0005856=cytoskeleton, 0005813=centrosome" "BcDNA:AT22559, CG15158" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR029527=Centrin-1" CG31802 16-Dec-15 2015_12 YOR257W(CDC31) viable FBgn0083235 EP454 EP454 http://flybase.net/reports/FBgn0083235.html gene 16-Dec-15 2015_12 FBgn0022765 Scruffy Scruffy http://flybase.net/reports/FBgn0022765.html gene Scf 16-Dec-15 2015_12 "visible,dominant,viable,wild-type,lethal,recessive" "tergite,anterior" FBgn0034611 MFS16 Major Facilitator Superfamily Transporter 16 http://flybase.net/reports/FBgn0034611.html protein_coding_gene 0015169=glycerol-3-phosphate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CG10069 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain, IPR000849=Sugar phosphate transporter" CG10069 16-Dec-15 2015_12 ENSDARG00000068658 "YLR004C(THI73),YJR152W(DAL5),YLL055W(YCT1)" "WBGene00011688(T10C6.6),WBGene00011717(T11G6.2),WBGene00011718(T11G6.3),WBGene00011719(T11G6.4)" ENSXETG00000003934(SLC37A2) "ENSMUSG00000032122(Slc37a2),ENSMUSG00000024036(Slc37a1)" "ENSG00000134955(SLC37A2),ENSG00000160190(SLC37A1)" "viable,fertile" FBgn0019732 l(1)A14 lethal (1) A14 http://flybase.net/reports/FBgn0019732.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085627 CG41346 http://flybase.net/reports/FBgn0085627.html FBan0041346 protein_coding_gene 16-Dec-15 2015_12 FBgn0266775 CR45240 http://flybase.net/reports/FBgn0266775.html non_protein_coding_gene CR45240 16-Dec-15 2015_12 FBgn0028159 l(3)S041415 lethal (3) S041415 http://flybase.net/reports/FBgn0028159.html gene 0414/15 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0266521 stai stathmin http://flybase.net/reports/FBgn0266521.html "FBgn0026184, FBgn0051641, FBgn0026568, FBgn0031780" protein_coding_gene "0008017=microtubule binding, 0015631=tubulin binding" "0008088=axon cargo transport, 0007017=microtubule-based process, 0031110=regulation of microtubule polymerization or depolymerization, 0007399=nervous system development, 0007298=border follicle cell migration, 0008354=germ cell migration, 0051124=synaptic growth at neuromuscular junction" "0005875=microtubule associated complex, 0031594=neuromuscular junction, 0005829=cytosol" "Stathmin, D-stat, SCG10-like, D-stathmin, LD33989, rdtp, CG5981, BEST:LD33989, CG31641, rdt, redtape" "IPR015880=Zinc finger, C2H2-like, IPR000956=Stathmin family" CG31641 16-Dec-15 2015_12 FBgn0000370 crc cryptocephal http://flybase.net/reports/FBgn0000370.html "FBgn0020511, FBgn0032941, FBtr0081512, FBpp0081040, FBtr0081513, FBpp0081041" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0001105=RNA polymerase II transcription coactivator activity, 0001102=RNA polymerase II activating transcription factor binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0046982=protein heterodimerization activity" "0007591=molting cycle, chitin-based cuticle, 0007552=metamorphosis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006641=triglyceride metabolic process, 0042594=response to starvation, 0005991=trehalose metabolic process, 0006355=regulation of transcription, DNA-templated, 0035073=pupariation, 0035074=pupation" 0005634=nucleus "Atf4, DM6, dATF-4, dATF4, CG8669, ATF4/crc, ATF4, Ire1, l(2)crc, Cryptocephal, 929, ATF-4" IPR004827=Basic-leucine zipper domain CG8669 16-Dec-15 2015_12 "ENSDARG00000039515(atf4b1),ENSDARG00000038141(atf4b2)" "ENSXETG00000024806(atf4),ENSXETG00000008804(BC076876.1),ENSXETG00000008803()" ENSG00000169136(ATF5) "starvation stress response defective,viable,fertile,partially lethal - majority die,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "pupal abdomen,adult head,ventral thoracic disc,anterior pupal spiracle,pupa,wing disc,cephalopharyngeal skeleton,wing,adult cuticle,leg,scutellum,scutellar bristle,haltere,adult thorax,dorsal" FBgn0015881 anon-48Aj anon-48Aj http://flybase.net/reports/FBgn0015881.html gene "XII, transcript group XII" 16-Dec-15 2015_12 FBgn0002362 l(3)87Ej lethal (3) 87Ej http://flybase.net/reports/FBgn0002362.html gene "l(3)G5, G5" 16-Dec-15 2015_12 lethal FBgn0037248 srl spargel http://flybase.net/reports/FBgn0037248.html FBan0009809 protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0030307=positive regulation of cell growth, 0001894=tissue homeostasis, 0010821=regulation of mitochondrion organization, 0006355=regulation of transcription, DNA-templated, 0097009=energy homeostasis, 0046627=negative regulation of insulin receptor signaling pathway, 0008286=insulin receptor signaling pathway" "0005634=nucleus, 0005737=cytoplasm, 0016607=nuclear speck" "dPGC1, dPCG1alpha, dPGC, PGC-1, Spargel, Srl, peroxisome proliferator-activated receptor gamma coactivator 1, dPGC-1, cg9809, spargel, CG9809, CG 9809, PGC-1-alpha" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG9809 16-Dec-15 2015_12 "small body,female sterile,developmental rate defective,wild-type,decreased cell size,cell autonomous,somatic clone,aging defective,short lived,long lived,fertile,RU486 conditional,viable" "fat body,lipid particle,mitochondrionda.G32,mitochondrial membraneda.G32,mitochondrionesg-05730B,mitochondrial membraneesg-05730B,adult hindgut,adult midgut" FBgn0266884 CR45345 http://flybase.net/reports/FBgn0266884.html non_protein_coding_gene CR45345 16-Dec-15 2015_12 FBgn0034866 Or59c Odorant receptor 59c http://flybase.net/reports/FBgn0034866.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "59c, DOR120, CG17226, 59E.2" "IPR004117=Olfactory receptor, Drosophila" CG17226 16-Dec-15 2015_12 viable FBgn0263090 CR43358 http://flybase.net/reports/FBgn0263090.html non_protein_coding_gene lincRNA.181 CR43358 16-Dec-15 2015_12 FBgn0031875 CG3430 http://flybase.net/reports/FBgn0031875.html protein_coding_gene 0042555=MCM complex IPR019140=Mini-chromosome maintenance complex-binding protein CG3430 16-Dec-15 2015_12 ENSDARG00000055314(c10orf119) ENSXETG00000010237(TEgg098e22.1) ENSMUSG00000048170(1110007A13Rik) ENSG00000197771(MCMBP) "viable,fertile" FBgn0000824 fs(1)K1563 female sterile (1) K1563 http://flybase.net/reports/FBgn0000824.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile soma-dependent,female sterile,semidominant,heat sensitive,recessive,viable" "egg,heat sensitive,chorion,dorsal appendage" FBgn0260124 2L1296 http://flybase.net/reports/FBgn0260124.html gene 16-Dec-15 2015_12 viable "embryonic/larval epidermis,somatic clone" FBgn0061047 l(3)S023450 lethal (3) S023450 http://flybase.net/reports/FBgn0061047.html gene 0234/50 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0016880 l(2)39DEe lethal (2) 39DEe http://flybase.net/reports/FBgn0016880.html gene C704 16-Dec-15 2015_12 lethal FBgn0001442 l(1)7Cd lethal (1) 7Cd http://flybase.net/reports/FBgn0001442.html gene 16-Dec-15 2015_12 lethal FBgn0261584 CG42694 http://flybase.net/reports/FBgn0261584.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG42694 16-Dec-15 2015_12 FBgn0026079 Nsun2 "NOP2-Sun domain family, member 2 ortholog" http://flybase.net/reports/FBgn0026079.html FBgn0029695 protein_coding_gene "0016428=tRNA (cytosine-5-)-methyltransferase activity, 0003723=RNA binding" "0007614=short-term memory, 0030488=tRNA methylation, 0001510=RNA methylation" "0005634=nucleus, 0005737=cytoplasm, 0005730=nucleolus" "dNsun2, EG:EG0007.9, CG6133" "IPR023267=RNA (C5-cytosine) methyltransferase, IPR023270=tRNA (C5-cytosine) methyltransferase, NCL1, IPR018314=Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR001678=SAM-dependent methyltransferase RsmB/NOP2-type" CG6133 16-Dec-15 2015_12 ENSDARG00000056665(nsun2) YBL024W(NCL1) WBGene00021686(Y48G8AL.5) ENSXETG00000001732(nsun2) ENSMUSG00000021595(Nsun2) ENSG00000037474(NSUN2) "viable,male fertile,female semi-fertile,memory defective" DRSC18662 E 0.852001195 0.245123923 2.711656978 -0.433023994 0.794947508 -0.105578776 FBgn0060477 l(3)S111505b lethal (3) S111505b http://flybase.net/reports/FBgn0060477.html gene 1115/05 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0083310 E(smoDN)1419 Enhancer of smoDN 1419 http://flybase.net/reports/FBgn0083310.html gene 16-Dec-15 2015_12 FBgn0000660 fl fluted http://flybase.net/reports/FBgn0000660.html gene 16-Dec-15 2015_12 visible wing FBgn0264891 CR44082 http://flybase.net/reports/FBgn0264891.html non_protein_coding_gene CR44082 16-Dec-15 2015_12 FBgn0020583 anon-59Cb anon-59Cb http://flybase.net/reports/FBgn0020583.html gene 16-Dec-15 2015_12 FBgn0083261 E(smoDN)830 Enhancer of smoDN 830 http://flybase.net/reports/FBgn0083261.html gene 16-Dec-15 2015_12 FBgn0001562 l(1)19Fb lethal (1) 19Fb http://flybase.net/reports/FBgn0001562.html gene "section 6, B214, 11, 6, l(1)B214, l(1)B-214, lB214-1, B-214, section 11, unnamed" 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "ovariole,germline clone,egg,dorsal appendage" FBgn0052517 CG32517 http://flybase.net/reports/FBgn0052517.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019880 anon-69Ac anon-69Ac http://flybase.net/reports/FBgn0019880.html gene 16-Dec-15 2015_12 larval stage FBgn0031002 CG14196 http://flybase.net/reports/FBgn0031002.html protein_coding_gene 0015355=secondary active monocarboxylate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG14196 16-Dec-15 2015_12 FBgn0002678 fs(2)abc female sterile abnormal chromatin http://flybase.net/reports/FBgn0002678.html gene "0007279=pole cell formation, 0007349=cellularization" "syn-PL63, abc, mat(2)synPL63, mat(2)syn-F" 16-Dec-15 2015_12 "female semi-sterile,recessive,female sterile,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,maternal effect,partially lethal - majority die" "syncytial blastoderm embryo,yolk nucleus,spindle,centrosome,aster,endochorion,pole cell,maternal effect,nucleus | embryonic stage 4" FBgn0259976 pag parva germina http://flybase.net/reports/FBgn0259976.html gene "0007283=spermatogenesis, 0048477=oogenesis" 16-Dec-15 2015_12 "viable,female sterile,recessive,male sterile" "female germline cell,ovariole,ovary,testis,male germline cell,female fusome,spectrosomevin7)" FBgn0263628 CR43637 http://flybase.net/reports/FBgn0263628.html non_protein_coding_gene CR43637 16-Dec-15 2015_12 FBgn0010816 l(3)03773 lethal (3) 03773 http://flybase.net/reports/FBgn0010816.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028367 l(1)10Al lethal (1) 10Al http://flybase.net/reports/FBgn0028367.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0024758 EC76 EC76 http://flybase.net/reports/FBgn0024758.html gene 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation" FBgn0051278 CG31278 http://flybase.net/reports/FBgn0051278.html FBgn0037825 protein_coding_gene "0042586=peptide deformylase activity, 0005506=iron ion binding" "PDF, CG6482" "IPR023635=Peptide deformylase, IPR000181=Formylmethionine deformylase" CG31278 16-Dec-15 2015_12 ENSDARG00000013950(zgc:114141) ENSXETG00000022729(pdf) ENSMUSG00000078931 ENSG00000157312 "viable,fertile" FBgn0063412 l(3)3450-K lethal (3) 3450-K http://flybase.net/reports/FBgn0063412.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0264508 CR43907 http://flybase.net/reports/FBgn0264508.html non_protein_coding_gene CR43907 16-Dec-15 2015_12 FBgn0003364 sesG stress-sensitive G http://flybase.net/reports/FBgn0003364.html gene 16-Dec-15 2015_12 "hyperactive,bang sensitive" FBgn0039476 CG6271 http://flybase.net/reports/FBgn0039476.html protein_coding_gene "0008970=phosphatidylcholine 1-acylhydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "Triglyceride lipase, DmelL1" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family, IPR002334=Vespid venom allergen phospholipase A1" CG6271 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) FBgn0033785 Sans Sans ortholog http://flybase.net/reports/FBgn0033785.html protein_coding_gene "0005769=early endosome, 0005737=cytoplasm" "Sans, DSANS, CG13320" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG13320 16-Dec-15 2015_12 "ENSDARG00000004322,ENSDARG00000036846(zgc:91874)" ENSXETG00000006846(USH1G) "ENSMUSG00000045288(Ush1g),ENSMUSG00000030909(Anks4b)" "ENSG00000182040(USH1G),ENSG00000175311(ANKS4B)" "viable,male fertile,female fertile,fertile,partially lethal - majority die,some die during pupal stage" DRSC06357 I 1.910247429 -0.186742376 0.435831611 0.454477484 -0.12212103 -0.361330162 FBgn0084825 C42 C42 http://flybase.net/reports/FBgn0084825.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0067878 Mod(Prat:bw)2-5 Mod(Prat:bw)2-5 http://flybase.net/reports/FBgn0067878.html gene Mod-2-5 16-Dec-15 2015_12 "visible,lethal,recessive,suppressor of variegation" wing FBgn0014112 anon-84Ba anon-84Ba http://flybase.net/reports/FBgn0014112.html gene Z 16-Dec-15 2015_12 embryonic stage && larval stage FBgn0265399 EP2081 http://flybase.net/reports/FBgn0265399.html gene 16-Dec-15 2015_12 FBgn0082979 snoRNA:ë¬28S-3091a snoRNA:ë¬28S-3091a http://flybase.net/reports/FBgn0082979.html snoRNA_gene "Psi 28S-3091a, psi28s-3091a, chr3R:1422405..1422506, CR34610" CR34610 16-Dec-15 2015_12 FBgn0014849 Eig71Ei Eig71Ei http://flybase.net/reports/FBgn0014849.html protein_coding_gene "0042742=defense response to bacterium, 0007552=metamorphosis" 0005576=extracellular region "CG7327, L71-9, EIG71-EI, L71" IPR003475=Insect protein of unknown function CG7327 16-Dec-15 2015_12 "viable,fertile" FBgn0063921 M(UAS-dsh)8-3 M(UAS-dsh)8-3 http://flybase.net/reports/FBgn0063921.html gene 0016055=Wnt signaling pathway UAS-dsh M[8-3] 16-Dec-15 2015_12 FBgn0262108 CR42861 http://flybase.net/reports/FBgn0262108.html non_protein_coding_gene CR42861 16-Dec-15 2015_12 FBgn0085611 CG41318 http://flybase.net/reports/FBgn0085611.html FBan0041318 protein_coding_gene 16-Dec-15 2015_12 FBgn0083309 E(smoDN)1422 Enhancer of smoDN 1422 http://flybase.net/reports/FBgn0083309.html gene 16-Dec-15 2015_12 FBgn0038139 PK2-R2 Pyrokinin 2 receptor 2 http://flybase.net/reports/FBgn0038139.html "FBgn0046554, FBgn0046555" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity, 0001653=peptide receptor activity, 0036401=pyrokinin receptor activity" "0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "Dm CG8795, CG8795, anon-WO0170980.194, Pyrokinin 2 receptor, anon-WO0170980.193" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG8795 16-Dec-15 2015_12 ENSDARG00000042939(gpr39) WBGene00016265(nmur-4) "viable,fertile,partially lethal - majority die,some die during pupal stage,lethal" DRSC16448 K 0.682739662 -1.029197156 -0.213406505 0.078407615 0.262222898 1.746703115 FBgn0010498 l(2)01848 lethal (2) 01848 http://flybase.net/reports/FBgn0010498.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0015977 l(2)PC4-C lethal (2) PC4-C http://flybase.net/reports/FBgn0015977.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038424 CG17565 http://flybase.net/reports/FBgn0038424.html protein_coding_gene 0004663=Rab geranylgeranyltransferase activity "0018343=protein farnesylation, 0042127=regulation of cell proliferation" "0005965=protein farnesyltransferase complex, 0005968=Rab-protein geranylgeranyltransferase complex" "FNTB, farnesyl transferase beta" "IPR026872=Protein farnesyltransferase subunit beta, IPR001330=PFTB repeat, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG17565 16-Dec-15 2015_12 ENSDARG00000027916(fntb) YDL090C(RAM1) WBGene00006465(fntb-1) ENSXETG00000002203(fntb) ENSMUSG00000033373(Churc1) ENSG00000125954(CHURC1-FNTB) "viable,visible,planar polarity defective" "mesothoracic tergum,wing | pupal stage,wing hair | pupal stage" FBgn0023046 l(1)3Aq lethal (1) 3Aq http://flybase.net/reports/FBgn0023046.html gene 1200D14 16-Dec-15 2015_12 "lethal,recessive" FBgn0034699 CG13504 http://flybase.net/reports/FBgn0034699.html protein_coding_gene 16-Dec-15 2015_12 DRSC22823 IE -1.9321045 0.483726101 -0.499286229 -1.838104186 -0.590274832 -0.610598497 FBgn0263633 mir-3644 mir-3644 stem loop http://flybase.net/reports/FBgn0263633.html "FBgn0262133, FBgn0263574" miRNA_gene CR43559 CR43559 16-Dec-15 2015_12 viable FBgn0013397 anon-96Fb anon-96Fb http://flybase.net/reports/FBgn0013397.html gene D transcript 16-Dec-15 2015_12 " adult stage , larval stage " " adult head

, eye-antennal disc

" FBgn0010325 K27 K27 http://flybase.net/reports/FBgn0010325.html gene 16-Dec-15 2015_12 FBgn0031008 CG8010 http://flybase.net/reports/FBgn0031008.html protein_coding_gene CG8010 16-Dec-15 2015_12 viable DRSC20072 K -0.329002261 0.762185957 -0.01478485 -0.100817361 1.501205961 0.34340924 FBgn0260874 Ir76a Ionotropic receptor 76a http://flybase.net/reports/FBgn0260874.html "FBgn0036907, FBgn0085286" protein_coding_gene "0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0050907=detection of chemical stimulus involved in sensory perception, 0019226=transmission of nerve impulse" "0016021=integral component of membrane, 0043235=receptor complex, 0016020=membrane, 0071683=sensory dendrite" "IR76a, ionotropic receptor 76a, DmelIR76a, CG42584, CG8533, CT24909, ir76a, CG34257" IPR001320=Ionotropic glutamate receptor CG42584 16-Dec-15 2015_12 FBgn0039951 CG12579 http://flybase.net/reports/FBgn0039951.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027966 l(3)S144912 lethal (3) S144912 http://flybase.net/reports/FBgn0027966.html gene 1449/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0003534 sto stocky http://flybase.net/reports/FBgn0003534.html gene "tapered-wings, tpw" 16-Dec-15 2015_12 "visible,recessive,viable,female sterile,partially,body color defective,male sterile,male,reduced" "wing,eye,adult abdomen,macrochaeta" FBgn0031918 CG6055 http://flybase.net/reports/FBgn0031918.html protein_coding_gene 0030246=carbohydrate binding "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin, IPR018378=C-type lectin, conserved site" CG6055 16-Dec-15 2015_12 viable FBgn0015473 l(2)45Aa lethal (2) 45Aa http://flybase.net/reports/FBgn0015473.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0032774 CG17549 http://flybase.net/reports/FBgn0032774.html protein_coding_gene CG17549 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0267506 pre-rRNA:CR45846 ribosomal RNA primary transcript:CR45846 http://flybase.net/reports/FBgn0267506.html rRNA_gene CR45846 CR45846 16-Dec-15 2015_12 FBgn0033656 S2P site-2 protease http://flybase.net/reports/FBgn0033656.html FBgn0062078 protein_coding_gene "0008237=metallopeptidase activity, 0004222=metalloendopeptidase activity" "0006508=proteolysis, 0035103=sterol regulatory element binding protein cleavage" 0016020=membrane "S2P, anon-WO0118547.346, dS2P, CG8988, ds2p" "IPR001193=Membrane-bound transcription factor site-2 protease, IPR008915=Peptidase M50, IPR001478=PDZ domain" CG8988 16-Dec-15 2015_12 ENSDARG00000057577(mbtps2) WBGene00013225(Y56A3A.2) ENSXETG00000025771(MBTPS2) ENSMUSG00000046873(Mbtps2) ENSG00000012174(MBTPS2) "viable,fertile,conditional,small body,lethal - all die before end of larval stage,some die during larval stage" FBgn0032474 DnaJ-H DnaJ homolog http://flybase.net/reports/FBgn0032474.html FBgn0046078 protein_coding_gene "0031072=heat shock protein binding, 0051082=unfolded protein binding" 0006457=protein folding "NEST:bs08d07, dnaJ-H, DNAJ-H, DNA J-H, dHdj2, CG9828, dDnaJ-H" "IPR018253=DnaJ domain, conserved site, IPR001623=DnaJ domain, IPR001305=Heat shock protein DnaJ, cysteine-rich domain, IPR002939=Chaperone DnaJ, C-terminal, IPR008971=HSP40/DnaJ peptide-binding" CG9828 16-Dec-15 2015_12 viable FBgn0053474 CG33474 http://flybase.net/reports/FBgn0053474.html protein_coding_gene 0016559=peroxisome fission 0005779=integral component of peroxisomal membrane "IPR026510=Peroxisomal membrane protein 11C, metazoa, IPR008733=Peroxisomal biogenesis factor 11" CG33474 16-Dec-15 2015_12 ENSDARG00000025559(zgc:114079) WBGene00004196(prx-11) ENSXETG00000001816(PEX11G) ENSMUSG00000069633(Pex11c) ENSG00000104883(PEX11G) FBgn0041734 mali mali http://flybase.net/reports/FBgn0041734.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,chemical resistant,dominant,lethal,recessive,hyperplasia" "salivary gland,melanotic mass,polytene chromosome,embryonic/larval brain" FBgn0036066 CG14160 http://flybase.net/reports/FBgn0036066.html protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG14160 16-Dec-15 2015_12 viable FBgn0004126 hum humilis http://flybase.net/reports/FBgn0004126.html gene 16-Dec-15 2015_12 "lethal,recessive,female sterile,viable" FBgn0000059 ag agametic http://flybase.net/reports/FBgn0000059.html gene 0008406=gonad development 16-Dec-15 2015_12 "grandchildless,semidominant" "pole cell,gonad" FBgn0014234 l(2)31Eq lethal (2) 31Eq http://flybase.net/reports/FBgn0014234.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037897 CG5270 http://flybase.net/reports/FBgn0037897.html protein_coding_gene 0046872=metal ion binding "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000306=FYVE zinc finger, IPR017455=Zinc finger, FYVE-related" CG5270 16-Dec-15 2015_12 ENSDARG00000053937 ENSXETG00000007653(ZFYVE26) ENSMUSG00000066440(Zfyve26) ENSG00000072121(ZFYVE26) viable FBgn0058458 2SrRNA:CR40458 2SrRNA:CR40458 http://flybase.net/reports/FBgn0058458.html rRNA_gene CR40458 16-Dec-15 2015_12 FBgn0040565 CG7606 http://flybase.net/reports/FBgn0040565.html protein_coding_gene CG7606 16-Dec-15 2015_12 FBgn0041147 ida imaginal discs arrested http://flybase.net/reports/FBgn0041147.html "FBgn0016008, FBgn0035472" protein_coding_gene 0090302=APC-Cdc20 complex activity "0007444=imaginal disc development, 0051726=regulation of cell cycle, 0022008=neurogenesis, 0045842=positive regulation of mitotic metaphase/anaphase transition, 0030162=regulation of proteolysis" "0005680=anaphase-promoting complex, 0005737=cytoplasm" "CG10850, IDA, APC5, l(3)63Fb, l(3)SH7, Imaginal discs arrested, Apc5" "IPR026000=Anaphase-promoting complex subunit 5, IPR011990=Tetratricopeptide-like helical domain" CG10850 16-Dec-15 2015_12 ENSDARG00000008461(anapc5) ENSXETG00000020963(ANAPC5) ENSMUSG00000029472(Anapc5) ENSG00000089053(ANAPC5) "neuroanatomy defective,mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of prepupal stage,some die during prepupal stage,female sterile,germline clone,viable,visible" "embryonic/larval brain,embryonic/larval optic lobe,testis,imaginal disc,air bubble,foregut imaginal ring,hindgut imaginal ring,salivary gland imaginal ring,midgut imaginal island,mitotic cell cycle,mitotic prometaphase,mitotic anaphase,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC08163 IE 2.227430572 0.534534691 2.062243328 -0.18819315 -0.692688187 -0.47589496 FBgn0027269 l(1)G0211 lethal (1) G0211 http://flybase.net/reports/FBgn0027269.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051796 CG31796 http://flybase.net/reports/FBgn0051796.html protein_coding_gene 16-Dec-15 2015_12 FBgn0037459 CG15184 http://flybase.net/reports/FBgn0037459.html protein_coding_gene 16-Dec-15 2015_12 DRSC12564 EK 0.679753286 1.268542767 0.262387438 2.001158041 0.309910891 1.831993351 FBgn0000985 fs(2)K female sterile (2) K http://flybase.net/reports/FBgn0000985.html gene "fes(2)K, fes(2)k" 16-Dec-15 2015_12 "female sterile,recessive,male fertile" FBgn0001735 l(1)HM3 lethal (1) HM3 http://flybase.net/reports/FBgn0001735.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female semi-sterile,heat sensitive" FBgn0016817 l(1)L2 lethal (1) L2 http://flybase.net/reports/FBgn0016817.html gene L2 16-Dec-15 2015_12 "lethal,recessive" FBgn0261673 nemy no extended memory http://flybase.net/reports/FBgn0261673.html "FBgn0033765, FBgn0044734, FBgn0033764, FBgn0040757" protein_coding_gene 0008805=carbon-monoxide oxygenase activity "0007626=locomotory behavior, 0007613=memory, 0007476=imaginal disc-derived wing morphogenesis" "0016021=integral component of membrane, 0030133=transport vesicle" "P153, no-extended memory, anon-WO0140519.146, cytochrome b561, CG8776, DcytB-like, CG13147, CytB561, Nemy" "IPR006593=Cytochrome b561/ferric reductase transmembrane, IPR004877=Cytochrome b561 domain" CG8776 16-Dec-15 2015_12 DRSC05357 K -0.149878689 -0.262002555 0.239305641 0.006167622 1.166674553 3.084038938 FBgn0031395 CG10874 http://flybase.net/reports/FBgn0031395.html protein_coding_gene 0005515=protein binding 0042384=cilium assembly 0005813=centrosome FBgn 31395 IPR025271=Domain of unknown function DUF4061 CG10874 16-Dec-15 2015_12 ENSXETG00000027651(CCDC28B) "ENSMUSG00000028795(Ccdc28b),ENSMUSG00000059554(Ccdc28a)" "ENSG00000160050(CCDC28B),ENSG00000024862(CCDC28A)" FBgn0001144 gs(1)N41 grandchildless N41 http://flybase.net/reports/FBgn0001144.html gene "0007097=nuclear migration, 0045448=mitotic cell cycle, embryonic" "gs(1)441, gs(1)N441" 16-Dec-15 2015_12 grandchildless cleavage nucleus FBgn0052166 CG32166 http://flybase.net/reports/FBgn0052166.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083277 E(smoDN)2546 Enhancer of smoDN 2546 http://flybase.net/reports/FBgn0083277.html gene 16-Dec-15 2015_12 FBgn0051921 CG31921 http://flybase.net/reports/FBgn0051921.html FBgn0045363 protein_coding_gene NEST:bs08h12 CG31921 16-Dec-15 2015_12 viable FBgn0267101 CR45541 http://flybase.net/reports/FBgn0267101.html non_protein_coding_gene CR45541 16-Dec-15 2015_12 FBgn0033957 CG12865 http://flybase.net/reports/FBgn0033957.html protein_coding_gene 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0027515 CG7115 http://flybase.net/reports/FBgn0027515.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0043169=cation binding" "0006470=protein dephosphorylation, 0008360=regulation of cell shape, 0007155=cell adhesion" "0005634=nucleus, 0005737=cytoplasm" "PP2C, BcDNA:LD21794" "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C, IPR000222=PPM-type phosphatase, divalent cation binding" CG7115 16-Dec-15 2015_12 "ENSDARG00000063218(zgc:154091),ENSDARG00000063571(LOC559782)" ENSMUSG00000027784(Ppm1l) ENSG00000163590(PPM1L) viable DRSC02000 E 0.3476742 0.258115545 -0.323878302 -1.818197598 0.636824272 -0.063677313 FBgn0031546 CG8851 http://flybase.net/reports/FBgn0031546.html protein_coding_gene 0022008=neurogenesis CG8851 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0023149 Su(mg)3-3 Suppressor of modifier of gypsy 3-3 http://flybase.net/reports/FBgn0023149.html gene 16-Dec-15 2015_12 FBgn0037418 Osi11 Osiris 11 http://flybase.net/reports/FBgn0037418.html protein_coding_gene 0005887=integral component of plasma membrane "CG15596, osi11, Osiris" IPR012464=Protein of unknown function DUF1676 CG15596 16-Dec-15 2015_12 viable FBgn0033232 CG12159 http://flybase.net/reports/FBgn0033232.html protein_coding_gene IPR009565=Protein of unknown function DUF1180 CG12159 16-Dec-15 2015_12 viable FBgn0065310 l(2)SH1954 lethal (2) SH1954 http://flybase.net/reports/FBgn0065310.html gene l(2)SH2 1954 16-Dec-15 2015_12 "lethal,recessive" FBgn0086546 MRE14 mRNA-like ncRNA in embryogenesis 14 http://flybase.net/reports/FBgn0086546.html non_protein_coding_gene GM10545 16-Dec-15 2015_12 FBgn0034290 CG5773 http://flybase.net/reports/FBgn0034290.html FBgn0063655 protein_coding_gene BcDNA:RH46075 CG5773 16-Dec-15 2015_12 DRSC06955 I -0.921156885 -3.165904852 -0.461414193 -1.41936047 -0.146770431 -0.594805759 FBgn0013277 Hsp70Ba Heat-shock-protein-70Ba http://flybase.net/reports/FBgn0013277.html "FBgn0001232, FBgn0051449" protein_coding_gene "0001666=response to hypoxia, 0035080=heat shock-mediated polytene chromosome puffing, 0009408=response to heat" 0005875=microtubule associated complex "Hsp-70, hsp70Ba, Protein 70, dhsp70, Hsp70B, hsp70B, heat-shock protein 70, hsp70 Ba, CG31449, Hsp70, Dm-hsp70, 87C locus, Hsp 70, heat shock protein 70BA, hsp-70, Hsp70(87C), hsp70b, dHsp70, heat shock 70, HSP70, hsp70 87C, hsp70" "IPR013126=Heat shock protein 70 family, IPR018181=Heat shock protein 70, conserved site, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR029047=Heat shock protein 70kD, peptide-binding domain" CG31449 16-Dec-15 2015_12 "heat stress response defective,viable" DRSC21247 IEK -0.467713773 -2.303890615 -1.000773181 -2.105013559 1.780812858 1.367888199 FBgn0015621 Clp Clipper http://flybase.net/reports/FBgn0015621.html FBgn0014034 protein_coding_gene "0004521=endoribonuclease activity, 0008270=zinc ion binding, 0003676=nucleic acid binding" "0006378=mRNA polyadenylation, 0022008=neurogenesis, 0006379=mRNA cleavage" 0005847=mRNA cleavage and polyadenylation specificity factor complex "CPSF30, CLP, CG3642, clp, Single stranded-binding protein c6a, c6a, Ssb-c6a, Cpsf30" "IPR001878=Zinc finger, CCHC-type, IPR000571=Zinc finger, CCCH-type" CG3642 16-Dec-15 2015_12 ENSDARG00000020217(nar) WBGene00044329(cpsf-4) "ENSXETG00000009892(BC080440.1),ENSXETG00000004641(TEgg060n16.1)" ENSMUSG00000029625(Cpsf4) ENSG00000160917(CPSF4) " embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage -- adult stage , embryonic stage | stage <5 , adult stage && oogenesis stage | stage S3-8 " " ovary

, organism

, oocyte | posterior

" " larval stage , oogenesis stage , adult stage && oogenesis stage " " oocyte

, follicle cell

" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" DRSC00746 I 1.518303126 2.724712601 0.158953175 -0.758051477 0.078246147 0.275961644 FBgn0025151 ms(2)A5 ms(2)A5 http://flybase.net/reports/FBgn0025151.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0024256 acd(2)5N30 auditory courtship defective 5N30 http://flybase.net/reports/FBgn0024256.html gene "0008049=male courtship behavior, 0031223=auditory behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective,courtship behavior defective,male sterile" testis FBgn0004105 flrd393 flight reduced 393 http://flybase.net/reports/FBgn0004105.html gene 0007629=flight behavior flrd-393 16-Dec-15 2015_12 "courtship behavior defective,male,flight defective" FBgn0037487 CG14608 http://flybase.net/reports/FBgn0037487.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14608 16-Dec-15 2015_12 viable FBgn0263453 CR43476 http://flybase.net/reports/FBgn0263453.html non_protein_coding_gene CR43476 16-Dec-15 2015_12 FBgn0017486 Su(crc)2 Suppressor of cryptocephal 2 http://flybase.net/reports/FBgn0017486.html gene Su2 16-Dec-15 2015_12 FBgn0000608 e(we) enhancer of white-eosin http://flybase.net/reports/FBgn0000608.html gene en-w[e] 16-Dec-15 2015_12 "female sterile,recessive,visible" "wing vein,wing" FBgn0259353 EP-687 http://flybase.net/reports/FBgn0259353.html gene 16-Dec-15 2015_12 visible "wing hair,wing margin,chaeta" FBgn0260750 Mulk Multi-substrate lipid kinase http://flybase.net/reports/FBgn0260750.html "FBgn0032206, FBgn0051873, FBgn0015866" protein_coding_gene 0001729=ceramide kinase activity "0006672=ceramide metabolic process, 0007280=pole cell migration" "Dmulk, CG18162, CG31873, Multi-substrate Lipid kinase, anon-31BCb" "IPR001206=Diacylglycerol kinase, catalytic domain, IPR016064=NAD kinase/diacylglycerol kinase-like domain" CG31873 16-Dec-15 2015_12 ENSDARG00000009837(agk) WBGene00018674(F52C9.3) ENSXETG00000020198(AGK) ENSMUSG00000029916(Agk) ENSG00000006530(AGK) DRSC02658 E 0.91469936 -0.864726558 -4.092363166 0.862479657 -0.264882746 0.524823966 FBgn0263197 Patronin Patronin http://flybase.net/reports/FBgn0263197.html "FBgn0262637, FBgn0022085, FBgn0034233, FBgn0034234, FBgn0034235, FBgn0034236, FBgn0050102, FBgn0053130, FBgn0063154" protein_coding_gene "0051011=microtubule minus-end binding, 0008017=microtubule binding" "0007026=negative regulation of microtubule depolymerization, 0000022=mitotic spindle elongation, 0051013=microtubule severing" "0005813=centrosome, 0005819=spindle, 0030496=midbody" "ssp4, BcDNA:LD17191, CG18459, CG18462, Ssp4, CG6516, lethal (2) k07433, CG33130, CG18460, short spindle 4, l(2)k07433, CG30102" "IPR001715=Calponin homology domain, IPR014797=CKK domain, IPR011033=PRC-barrel-like, IPR022613=Calmodulin-regulated spectrin-associated protein, CH domain" CG33130 16-Dec-15 2015_12 "ENSDARG00000062173(camsap1l1),ENSDARG00000059965(LOC558673),ENSDARG00000035122(camsap1b),ENSDARG00000059475(si:dkey-209e8.1)" WBGene00004121(pqn-34) "ENSXETG00000005227(CAMSAP1L1),ENSXETG00000021592(CAMSAP1),ENSXETG00000002610(KIAA1543)" "ENSMUSG00000026933(Camsap1),ENSMUSG00000041570(Camsap1l1)" "ENSG00000130559(CAMSAP1),ENSG00000118200(CAMSAP1L1)" FBgn0005462 l(1)ts19 lethal (1) ts19 http://flybase.net/reports/FBgn0005462.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0005588 anon-alaE anon-alaE http://flybase.net/reports/FBgn0005588.html repeat_region "ALA-E6, ala-E, ala-B" 16-Dec-15 2015_12 FBgn0037307 Tim17a2 Tim17a2 http://flybase.net/reports/FBgn0037307.html FBgn0047052 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0015031=protein transport, 0006626=protein targeting to mitochondrion" 0005744=mitochondrial inner membrane presequence translocase complex "BcDNA:RH03914, CG14666" "IPR005678=Mitochondrial inner membrane translocase complex, subunit Tim17, IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24" CG14666 16-Dec-15 2015_12 YJL143W(TIM17) "viable,visible" trichogen cell FBgn0267323 CR45759 http://flybase.net/reports/FBgn0267323.html non_protein_coding_gene lincRNA.458 CR45759 16-Dec-15 2015_12 FBgn0259203 CG42307 http://flybase.net/reports/FBgn0259203.html protein_coding_gene CG42307 16-Dec-15 2015_12 FBgn0042101 CG18744 http://flybase.net/reports/FBgn0042101.html protein_coding_gene "IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain, IPR014756=Immunoglobulin E-set" CG18744 16-Dec-15 2015_12 viable FBgn0033136 Tsp42Eo Tetraspanin 42Eo http://flybase.net/reports/FBgn0033136.html FBgn0062933 protein_coding_gene 0016021=integral component of membrane "Dm.Tsp42Eo, BcDNA:RH51444, CG12838, tetraspanin 42E" "IPR000301=Tetraspanin, IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG12838 16-Dec-15 2015_12 viable FBgn0060906 l(3)S043418 lethal (3) S043418 http://flybase.net/reports/FBgn0060906.html gene 0434/18 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031657 CG3756 http://flybase.net/reports/FBgn0031657.html protein_coding_gene "0046983=protein dimerization activity, 0003899=DNA-directed RNA polymerase activity" "0006360=transcription from RNA polymerase I promoter, 0006351=transcription, DNA-templated, 0006383=transcription from RNA polymerase III promoter" "0005875=microtubule associated complex, 0005666=DNA-directed RNA polymerase III complex, 0005736=DNA-directed RNA polymerase I complex" "IPR011262=DNA-directed RNA polymerase, insert domain, IPR009025=DNA-directed RNA polymerase, RBP11-like dimerisation domain, IPR011263=DNA-directed RNA polymerase, RpoA/D/Rpb3-type" CG3756 16-Dec-15 2015_12 ENSDARG00000039400(polr1c) YPR110C(RPC40) WBGene00019275(H43I07.2) ENSXETG00000010882(POLR1C) ENSMUSG00000067148(Polr1c) ENSG00000171453(POLR1C) viable FBgn0044402 Scim25 Sensitized chromosome inheritance modifier 25 http://flybase.net/reports/FBgn0044402.html gene "0007062=sister chromatid cohesion, 0016321=female meiosis chromosome segregation, 0007067=mitotic nuclear division" 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "mitosis & nuclear chromosome,mitotic interphase,nuclear chromosome" FBgn0001052 Fs(3)Jut Female sterile (3) Jutas http://flybase.net/reports/FBgn0001052.html gene 0040016=embryonic cleavage "Fs(3)Sz13, Fs(3)Jutas, Jut" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0014306 l(3)neo53b lethal (3) neo53b http://flybase.net/reports/FBgn0014306.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043565 Su(hh)II Su(hh)II http://flybase.net/reports/FBgn0043565.html gene 16-Dec-15 2015_12 FBgn0011318 l(3)j1E7 lethal (3) j1E7 http://flybase.net/reports/FBgn0011318.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,polyphasic,recessive,female sterile" "ovariole,germline clone,egg" FBgn0051383 tRNA:CR31383 transfer RNA:CR31383 http://flybase.net/reports/FBgn0051383.html FBgn0060148 tRNA_gene 0033419=CUA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:L:TAG:AE002708-b, CR31383, AE002708.trna33-LeuTAG, chr3R.trna39-LeuTAG" CR31383 16-Dec-15 2015_12 FBgn0086234 whale whale http://flybase.net/reports/FBgn0086234.html gene 16-Dec-15 2015_12 FBgn0031882 Rab30 Rab30 http://flybase.net/reports/FBgn0031882.html protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding" "0046529=imaginal disc fusion, thorax closure, 0015031=protein transport, 0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction, 0008258=head involution, 0007391=dorsal closure, 0007390=germ-band shortening" "0005802=trans-Golgi network, 0005794=Golgi apparatus, 0045202=synapse, 0031982=vesicle, 0031410=cytoplasmic vesicle, 0005768=endosome" "AAF52477, DmRab30, rab30, Rab-30, CG9100, Q9VM50" "IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9100 16-Dec-15 2015_12 ENSDARG00000037884(rab30) WBGene00004282(rab-30) ENSXETG00000013633(rab30) ENSMUSG00000030643(Rab30) ENSG00000137502(RAB30) "partially lethal - majority die,visible" "adult thorax,mesothoracic tergum,adult thoracic sensillum,scutellum,embryonic epidermis,dorsal,embryonic head" FBgn0265584 CR44411 http://flybase.net/reports/FBgn0265584.html non_protein_coding_gene CR44411 16-Dec-15 2015_12 FBgn0267682 CR46018 http://flybase.net/reports/FBgn0267682.html non_protein_coding_gene CR46018 16-Dec-15 2015_12 FBgn0052370 tRNA:CR32370 transfer RNA:CR32370 http://flybase.net/reports/FBgn0052370.html FBgn0060289 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna45-AlaAGC, tRNA:A:AGC:AE002602, tRNA[[Ala]], CR32370, AE002602.trna11-AlaAGC" CR32370 16-Dec-15 2015_12 FBgn0065538 l(2)SH1068 lethal (2) SH1068 http://flybase.net/reports/FBgn0065538.html gene l(2)SH2 1068 16-Dec-15 2015_12 "lethal,recessive" FBgn0026015 Top3ë_ Topoisomerase 3ë_ http://flybase.net/reports/FBgn0026015.html protein_coding_gene "0003916=DNA topoisomerase activity, 0004520=endodeoxyribonuclease activity, 0003677=DNA binding, 0003917=DNA topoisomerase type I activity" "0006265=DNA topological change, 0051965=positive regulation of synapse assembly, 0000737=DNA catabolic process, endonucleolytic" "top3beta, Topoisomerase 3, top3[beta], Top3beta, Topo IIIbeta, Top3, dTop3beta, Top 3beta, Topoisomerase 3beta, topo III[beta], CG3458, top3, TOP3, topoisomerase 3beta" "IPR000380=DNA topoisomerase, type IA, IPR023406=DNA topoisomerase, type IA, active site, IPR006171=Toprim domain, IPR013824=DNA topoisomerase, type IA, central region, subdomain 1, IPR013826=DNA topoisomerase, type IA, central region, subdomain 3, IPR013497=DNA topoisomerase, type IA, central, IPR003601=DNA topoisomerase, type IA, domain 2, IPR003602=DNA topoisomerase, type IA, DNA-binding domain, IPR023405=DNA topoisomerase, type IA, core domain, IPR013825=DNA topoisomerase, type IA, central region, subdomain 2" CG3458 16-Dec-15 2015_12 ENSDARG00000027586(LOC100329289) YLR234W(TOP3) WBGene00012995(Y48C3A.14) ENSXETG00000018565(TOP3B) ENSMUSG00000022779(Top3b) ENSG00000100038(TOP3B) embryonic stage -- adult stage "neuroanatomy defective,viable,fertile" "embryonic/larval neuromuscular junction,NMJ bouton" FBgn0001016 fs(3)A7 female sterile (3) A7 http://flybase.net/reports/FBgn0001016.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0062610 Mod(var)1317 Mod(var)1317 http://flybase.net/reports/FBgn0062610.html gene 0006342=chromatin silencing 1317 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0067727 mez mertz http://flybase.net/reports/FBgn0067727.html gene "0045450=bicoid mRNA localization, 0045451=pole plasm oskar mRNA localization" 16-Dec-15 2015_12 lethal "egg,germline clone" FBgn0265954 CR44741 http://flybase.net/reports/FBgn0265954.html non_protein_coding_gene CR44741 16-Dec-15 2015_12 FBgn0004130 l(2)43Da lethal (2) 43Da http://flybase.net/reports/FBgn0004130.html gene 43Da 16-Dec-15 2015_12 lethal FBgn0262779 Su(E1)-M http://flybase.net/reports/FBgn0262779.html gene 16-Dec-15 2015_12 FBgn0039593 Sid Stress induced DNase http://flybase.net/reports/FBgn0039593.html protein_coding_gene "0004536=deoxyribonuclease activity, 0004540=ribonuclease activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0009617=response to bacterium, 1901562=response to paraquat, 0006979=response to oxidative stress" "0016020=membrane, 0005737=cytoplasm" "sid, Stress Induced DNase, CG9989" "IPR020821=Extracellular Endonuclease, subunit A, IPR001604=DNA/RNA non-specific endonuclease" CG9989 16-Dec-15 2015_12 FBgn0264916 CR44107 http://flybase.net/reports/FBgn0264916.html non_protein_coding_gene CR44107 16-Dec-15 2015_12 FBgn0038773 CG10887 http://flybase.net/reports/FBgn0038773.html protein_coding_gene "0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter" 0016593=Cdc73/Paf1 complex IPR007149=Leo1-like protein CG10887 16-Dec-15 2015_12 viable DRSC27820 K 0.068846572 -1.153143284 0.082754422 0.322834243 -2.403463983 -0.65468178 FBgn0019819 ecp eclipse http://flybase.net/reports/FBgn0019819.html gene ecl 16-Dec-15 2015_12 "viable,fertile,eye color defective" pigment cell FBgn0058170 CG40170 http://flybase.net/reports/FBgn0058170.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029711 Usf Usf http://flybase.net/reports/FBgn0029711.html protein_coding_gene "0046983=protein dimerization activity, 0070888=E-box binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006351=transcription, DNA-templated" 0005634=nucleus "DmUsf, dUSF2, bHLHb13, dUSF, Dm Usf, CG17592" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG17592 16-Dec-15 2015_12 "ENSDARG00000014463(usf2),ENSDARG00000041689(usf1),ENSDARG00000020228(si:dkey-211g8.3),ENSDARG00000021079" "ENSMUSG00000058239(Usf2),ENSMUSG00000026641(Usf1)" "ENSG00000105698(USF2),ENSG00000158773(USF1)" viable FBgn0002939 ninaD neither inactivation nor afterpotential D http://flybase.net/reports/FBgn0002939.html "FBgn0032662, FBgn0051783" protein_coding_gene 0005044=scavenger receptor activity "0007604=phototransduction, UV, 0016063=rhodopsin biosynthetic process, 0006952=defense response, 0007602=phototransduction, 0007603=phototransduction, visible light, 0046867=carotenoid transport, 0007155=cell adhesion" "0005887=integral component of plasma membrane, 0016020=membrane" "CG31783, NINAD, CG5750" IPR002159=CD36 antigen CG31783 16-Dec-15 2015_12 ENSXETG00000001195(SCARB1) "neurophysiology defective,viable" photoreceptor cell FBgn0067769 glissade glissade http://flybase.net/reports/FBgn0067769.html gene 0045451=pole plasm oskar mRNA localization gls 16-Dec-15 2015_12 "nurse cell,germline clone,egg chamber" FBgn0001786 l(1)M84 lethal (1) M84 http://flybase.net/reports/FBgn0001786.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0038342 B9d1 B9d1 http://flybase.net/reports/FBgn0038342.html protein_coding_gene 0042384=cilium assembly 0035869=ciliary transition zone "CG14870, B9D1" IPR010796=B9 domain CG14870 16-Dec-15 2015_12 ENSDARG00000011727(b9d1) ENSXETG00000022659(BC091609.1) ENSMUSG00000001039(B9d1) ENSG00000108641(B9D1) viable FBgn0011698 prp prickly pear http://flybase.net/reports/FBgn0011698.html gene 16-Dec-15 2015_12 FBgn0266442 CG45072 http://flybase.net/reports/FBgn0266442.html protein_coding_gene CG18682 CG45072 16-Dec-15 2015_12 viable FBgn0040708 CG15421 http://flybase.net/reports/FBgn0040708.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033669 PI31 http://flybase.net/reports/FBgn0033669.html protein_coding_gene "0007140=male meiosis, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0008584=male gonad development, 0043248=proteasome assembly, 0006974=cellular response to DNA damage stimulus" 0070864=sperm individualization complex "8979, DmPI31, dmPI31, cg8979, CG8979" "IPR021625=PI31 proteasome regulator, N-terminal" CG8979 16-Dec-15 2015_12 ENSDARG00000022652(zgc:92785) ENSMUSG00000032869(Psmf1) ENSG00000125818(PSMF1) "meiotic cell cycle defective,lethal,recessive,melanotic mass phenotype,body size defective,developmental rate defective,visible,body color defective,partially lethal - majority die,some die during pupal stage" "male germline cyst,trichogen cell,mesothoracic tergum,wing,tarsal segment,arista" FBgn0061087 l(3)S011832 lethal (3) S011832 http://flybase.net/reports/FBgn0061087.html gene 0118/32 16-Dec-15 2015_12 "lethal,recessive" FBgn0042701 CR12628 Microsomal glutathione S-transferase-like pseudogene http://flybase.net/reports/FBgn0042701.html "FBan0012628, FBgn0032985" pseudogene_attribute "Mgstl-Psi, CG12628, CT35150" CR12628 16-Dec-15 2015_12 FBgn0017381 l(1)3-64 lethal (1) 3-64 http://flybase.net/reports/FBgn0017381.html gene "3-64, lethal(1)3-64" 16-Dec-15 2015_12 "lethal,recessive" FBgn0002733 E(spl)më_-HLH "Enhancer of split më_, helix-loop-helix" http://flybase.net/reports/FBgn0002733.html protein_coding_gene "0046983=protein dimerization activity, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007219=Notch signaling pathway, 0007399=nervous system development, 0045892=negative regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development" 0005634=nucleus "HLHmbeta, E(spl)mbeta-HLH, Mbeta, E(spl)mbeta, mA, E(spl)beta, HLH-mbeta, E(spl) region transcript mbeta, E(spl)mbeta}, E(spl)-mbeta, Dm-mA, unnamed, m-beta, E(spl)mA, Enhancer of split m-beta, split locus enhancer protein mA, HLHmA, CG14548, E(spl)-Mbeta, E(spl), E(spl)mb, mbeta, Enhancer of split mbeta, HLHMbeta, E(Spl)mbeta, mb, E(spl) mbeta, E(Spl) HLH-Mbeta, E(spl)Mbeta, Enhancer of split region transcript HLHmA, bHLHb34" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG14548 16-Dec-15 2015_12 ENSDARG00000014722(her1) "visible,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "scutellar bristle,anterior crossvein,wing vein,macrochaeta,microchaeta,wing vein L5,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutum & macrochaetah-1J3,wing & macrochaetaptc-559.1,scutum & macrochaetaptc-559.1,ectopic" FBgn0267885 CR46173 http://flybase.net/reports/FBgn0267885.html pseudogene_attribute CG12717-related CR46173 16-Dec-15 2015_12 FBgn0061033 l(3)S023943 lethal (3) S023943 http://flybase.net/reports/FBgn0061033.html gene 0239/43 16-Dec-15 2015_12 "lethal,recessive" FBgn0028580 ms(2)35Bi male sterile (2) 35Bi http://flybase.net/reports/FBgn0028580.html gene 0007283=spermatogenesis ms(2)35Bi 16-Dec-15 2015_12 "male sterile,recessive" FBgn0005043 E(var)29BD Enhancer of variegation 29BD http://flybase.net/reports/FBgn0005043.html gene unnamed 16-Dec-15 2015_12 FBgn0005660 Ets21C Ets at 21C http://flybase.net/reports/FBgn0005660.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0042742=defense response to bacterium, 0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "ets21C, D-Ets-6, D-Ets6, D-ets-6, Ets6, Ets, ETS6, CG2914, ets21c" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain, IPR013761=Sterile alpha motif/pointed domain, IPR003118=Pointed domain" CG2914 16-Dec-15 2015_12 "ENSDARG00000054632(fli1a),ENSDARG00000040080(fli1b)" embryonic stage ventral nerve cord | restricted

"viable,fertile" FBgn0263980 CG43729 http://flybase.net/reports/FBgn0263980.html "FBan0008179, FBgn0034020, FBgn0085347, FBgn0050470, FBgn0034017, FBgn0034019, FBgn0034018, FBgn0085394, FBgn0262868" protein_coding_gene 0019992=diacylglycerol binding "0035556=intracellular signal transduction, 0045793=positive regulation of cell size, 0046331=lateral inhibition" "CG12958, Dm_2R:47664, CG34318, CG8179, Dm_2R:47672, CG30470, CG18625, CG12959, CG34365, CG14163, mdcds_11908, CG34318/CG34365/CG8179, CG43223" "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001452=SH3 domain" CG43729 16-Dec-15 2015_12 "ENSXETG00000023709(STAC2),ENSXETG00000004974(STAC),ENSXETG00000017156(stac3)" DRSC23183 K 1.706486097 1.875032981 FBgn0034452 Oseg6 Outer segment 6 http://flybase.net/reports/FBgn0034452.html protein_coding_gene "0042384=cilium assembly, 0035058=nonmotile primary cilium assembly" "0030991=intraciliary transport particle A, 0031513=nonmotile primary cilium" "oseg6, Wdr19, OSEG6, OSEG, Oseg6, CG11237, WDR19" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG11237 16-Dec-15 2015_12 ENSDARG00000037406 WBGene00001118(dyf-2) ENSXETG00000012870() ENSMUSG00000037890(Wdr19) ENSG00000157796(WDR19) viable FBgn0045978 PdL2B1 PdL2B1 http://flybase.net/reports/FBgn0045978.html gene unnamed 16-Dec-15 2015_12 "lethal,short lived,viable" FBgn0266235 CR44930 http://flybase.net/reports/FBgn0266235.html non_protein_coding_gene lincRNA.697 CR44930 16-Dec-15 2015_12 FBgn0015942 ftz::prd ftz::prd http://flybase.net/reports/FBgn0015942.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0023021 l(3)S001407b lethal (3) S001407b http://flybase.net/reports/FBgn0023021.html gene "14/7, l(3)S001407, 0014/07" 16-Dec-15 2015_12 "lethal,recessive" FBgn0037254 CG14651 http://flybase.net/reports/FBgn0037254.html FBan0014651 protein_coding_gene "0016887=ATPase activity, 0003777=microtubule motor activity" 0003341=cilium movement 0005858=axonemal dynein complex "IPR013602=Dynein heavy chain, domain-2, IPR026975=Dynein heavy chain 1, axonemal, IPR026983=Dynein heavy chain" CG14651 16-Dec-15 2015_12 viable FBgn0040802 CG12329 http://flybase.net/reports/FBgn0040802.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028681 SW140 SW140 http://flybase.net/reports/FBgn0028681.html gene unnamed 16-Dec-15 2015_12 viable FBgn0000973 fs(2)HO8 female sterile (2) HO8 http://flybase.net/reports/FBgn0000973.html gene fs(2)8B 16-Dec-15 2015_12 "female sterile,recessive" ovary FBgn0032835 CG16772 http://flybase.net/reports/FBgn0032835.html FBgn0044789 protein_coding_gene anon-WO0138581.5 CG16772 16-Dec-15 2015_12 viable FBgn0038849 CG7079 http://flybase.net/reports/FBgn0038849.html protein_coding_gene 0005615=extracellular space cg7079 IPR010562=Haemolymph juvenile hormone binding CG7079 16-Dec-15 2015_12 FBgn0262109 CR42862 http://flybase.net/reports/FBgn0262109.html "FBgn0052477, FBgn0025239, FBgn0035115, FBgn0046806, FBgn0260457, FBgn0035114" non_protein_coding_gene "CG16971, CG13878, anon-fast-evolving-1H7, BcDNA:GH06422, CR32477, CG32477, anon-EST:fe1H7" CR42862 16-Dec-15 2015_12 DRSC36563 EK -0.113180111 0.151278683 1.758689469 0.85449034 3.083665337 -0.224693987 FBgn0003167 pur purplish ruby http://flybase.net/reports/FBgn0003167.html gene 16-Dec-15 2015_12 "viable,recessive,eye color defective,visible" pigment cell FBgn0031417 CG3597 http://flybase.net/reports/FBgn0031417.html protein_coding_gene 0016491=oxidoreductase activity BVRA "IPR000683=Oxidoreductase, N-terminal, IPR016040=NAD(P)-binding domain" CG3597 16-Dec-15 2015_12 YML051W(GAL80) viable FBgn0065968 l(2)SH0007 lethal (2) SH0007 http://flybase.net/reports/FBgn0065968.html gene l(2)SH2 0007 16-Dec-15 2015_12 "lethal,recessive" FBgn0065935 l(2)SH0126 lethal (2) SH0126 http://flybase.net/reports/FBgn0065935.html gene l(2)SH2 0126 16-Dec-15 2015_12 "lethal,recessive" FBgn0020644 Lcp65Ab1 Lcp65Ab1 http://flybase.net/reports/FBgn0020644.html "FBgn0002536, FBgn0002540, FBgn0042117, FBgn0052400" protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0040003=chitin-based cuticle development, 0008363=larval chitin-based cuticle development" "0031012=extracellular matrix, 0005576=extracellular region" "LCP5, Lcp65A-b, Lcp-b1, Lcp65Abl, Lcp65Ab, Rho, Larval cuticle protein 10, Lcp10, CG18776, LCP65Ab1, Lcp-b, DCP-alpha, LCP10, CG32400, L[[3]]CP5, Lcp5, LCP-5, CP5" IPR000618=Insect cuticle protein CG32400 16-Dec-15 2015_12 " embryonic stage , larval stage " "electrophoretic variant,fast,slow" FBgn0026355 Su(SuRaf1)12 Su(SuRaf1)12 http://flybase.net/reports/FBgn0026355.html gene Su[Su(Raf)1]12 16-Dec-15 2015_12 "lethal,recessive" FBgn0262965 CR43276 http://flybase.net/reports/FBgn0262965.html pseudogene_attribute CR43276 16-Dec-15 2015_12 FBgn0034061 CG8386 http://flybase.net/reports/FBgn0034061.html protein_coding_gene 0046331=lateral inhibition "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR014806=Ubiquitin-fold modifier-conjugating enzyme 1" CG8386 16-Dec-15 2015_12 ENSDARG00000022340(ufc1) WBGene00008041(C40H1.6) ENSXETG00000017667(UFC1) ENSMUSG00000062963(Ufc1) ENSG00000143222(UFC1) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,tormogen cell" FBgn0085410 TrissinR Trissin receptor http://flybase.net/reports/FBgn0085410.html "FBgn0046569, FBgn0031744, FBgn0031743, FBgn0046570, FBgn0031742, FBgn0051645" protein_coding_gene "0008188=neuropeptide receptor activity, 0008528=G-protein coupled peptide receptor activity, 0004930=G-protein coupled receptor activity, 0004950=chemokine receptor activity" "0006935=chemotaxis, 0007186=G-protein coupled receptor signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "CG14004, CG14003, CG34381, trissin receptor, CG31645, anon-WO0170980.173, CG14002, anon-WO0170980.172" "IPR000355=Chemokine receptor family, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG34381 16-Dec-15 2015_12 "ENSDARG00000035236(npffr2.1),ENSDARG00000060702,ENSDARG00000033635(LOC564758)" WBGene00011578(T07D4.1) viable DRSC02335 IE -0.38479675 -3.247420011 -0.551870295 -1.878198683 -1.222471429 0.039422164 FBgn0004789 Indnc In dunce http://flybase.net/reports/FBgn0004789.html gene indnc 16-Dec-15 2015_12 FBgn0005229 l(3)R4 lethal of Roberts 4 http://flybase.net/reports/FBgn0005229.html gene l(3)B4 16-Dec-15 2015_12 "lethal,polyphasic,recessive" FBgn0266346 CngB Cyclic nucleotide-gated ion channel subunit B http://flybase.net/reports/FBgn0266346.html "FBgn0034656, FBgn0024813" protein_coding_gene 0005221=intracellular cyclic nucleotide activated cation channel activity "0006812=cation transport, 0019935=cyclic-nucleotide-mediated signaling, 0055085=transmembrane transport" 0017071=intracellular cyclic nucleotide activated cation channel complex "dCNCbeta, dmCNGB, Cyclic-nucleotide-gated ion channel protein beta-subunit, CG17922, Cncbeta" "IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain, IPR005821=Ion transport domain, IPR014710=RmlC-like jelly roll fold, IPR018488=Cyclic nucleotide-binding, conserved site" CG17922 16-Dec-15 2015_12 "ENSDARG00000042107,ENSDARG00000068242,ENSDARG00000061945(LOC562675)" WBGene00006525(tax-2) "ENSXETG00000013750(CNGB1),ENSXETG00000013712(CNGB3)" "ENSMUSG00000031789,ENSMUSG00000056494(Cngb3)" "ENSG00000070729(CNGB1),ENSG00000170289(CNGB3)" FBgn0067761 l(1)G0001 lethal (1) G0001 http://flybase.net/reports/FBgn0067761.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0011637 l(3)Lak lethal(3)Laker http://flybase.net/reports/FBgn0011637.html gene l(3)Lkr 16-Dec-15 2015_12 "flightless,dominant,lethal,recessive" FBgn0262577 CG43117 http://flybase.net/reports/FBgn0262577.html protein_coding_gene CG43117 16-Dec-15 2015_12 FBgn0030167 CG15252 http://flybase.net/reports/FBgn0030167.html protein_coding_gene CG15252 16-Dec-15 2015_12 viable FBgn0263940 BG00037 http://flybase.net/reports/FBgn0263940.html gene 16-Dec-15 2015_12 "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0052774 Muc4B Mucin 4B http://flybase.net/reports/FBgn0052774.html "FBgn0029699, FBgn0040903" protein_coding_gene 0005201=extracellular matrix structural constituent 0007306=eggshell chorion assembly "0042600=chorion, 0031012=extracellular matrix" "muc4B, Muc4B, CG15575, CG32774, CG15574" CG32774 16-Dec-15 2015_12 "lethal,partially lethal - majority die,visible" trichogen cell DRSC18063 IE -0.108804632 -1.83696519 -0.322308662 -1.842539069 1.230322538 0.938912377 FBgn0016877 l(2)39DEb lethal (2) 39DEb http://flybase.net/reports/FBgn0016877.html gene C87 16-Dec-15 2015_12 lethal FBgn0086295 aspn aspiny http://flybase.net/reports/FBgn0086295.html gene 0046847=filopodium assembly 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0037365 CG2104 http://flybase.net/reports/FBgn0037365.html protein_coding_gene 0008160=protein tyrosine phosphatase activator activity "IPR004327=Phosphotyrosyl phosphatase activator, PTPA" CG2104 16-Dec-15 2015_12 YIL153W(RRD1) ENSXETG00000018970(PPP2R4) viable FBgn0045972 PdL73A1 PdL73A1 http://flybase.net/reports/FBgn0045972.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0058192 CG40192 http://flybase.net/reports/FBgn0058192.html protein_coding_gene 16-Dec-15 2015_12 FBgn0032234 gny garnysstan http://flybase.net/reports/FBgn0032234.html protein_coding_gene 0046527=glucosyltransferase activity "0040003=chitin-based cuticle development, 0006487=protein N-linked glycosylation" "0005789=endoplasmic reticulum membrane, 0005783=endoplasmic reticulum" "alg6, dAlg6, Gny[, Dalg6, CG5091" "IPR004856=Glycosyl transferase, ALG6/ALG8" CG5091 16-Dec-15 2015_12 ENSDARG00000017617(alg6) YOR002W(ALG6) WBGene00007435(C08B11.8) ENSXETG00000010835(ALG6) ENSMUSG00000073792(Alg6) ENSG00000088035(ALG6) "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable" "cephalopharyngeal skeleton,germline clone,embryonic/first instar larval cuticle,denticle" FBgn0065126 l(3)SH140 lethal (3) SH140 http://flybase.net/reports/FBgn0065126.html gene l(2)SH3 140 16-Dec-15 2015_12 "lethal,recessive" FBgn0015962 l(2)46Cp lethal (2) 46Cp http://flybase.net/reports/FBgn0015962.html gene group 4 16-Dec-15 2015_12 "lethal,recessive" FBgn0040791 CG13697 http://flybase.net/reports/FBgn0040791.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060375 l(3)S136414b lethal (3) S136414b http://flybase.net/reports/FBgn0060375.html gene 1364/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0004978 ats abnormal tarsi http://flybase.net/reports/FBgn0004978.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,female sterile,lethal,partially,some die during immature adult stage" "tarsal segment,tarsal segment 2,tarsal segment 3,tarsal segment 4,metatarsus,pretarsus" FBgn0267567 CR45907 http://flybase.net/reports/FBgn0267567.html non_protein_coding_gene CR45907 16-Dec-15 2015_12 FBgn0045975 PdL43C1 PdL43C1 http://flybase.net/reports/FBgn0045975.html gene unnamed 16-Dec-15 2015_12 "lethal,short lived,recessive" FBgn0266317 CR44982 http://flybase.net/reports/FBgn0266317.html non_protein_coding_gene CR44982 16-Dec-15 2015_12 FBgn0259736 CG42390 http://flybase.net/reports/FBgn0259736.html "FBgn0053334, FBgn0038932" protein_coding_gene "CG33334, CG5740" CG42390 16-Dec-15 2015_12 FBgn0266646 CR45153 http://flybase.net/reports/FBgn0266646.html non_protein_coding_gene CR45153 16-Dec-15 2015_12 FBgn0015887 anon-6Ea anon-6Ea http://flybase.net/reports/FBgn0015887.html gene 16-Dec-15 2015_12 FBgn0033264 Nup50 Nucleoporin 50kD http://flybase.net/reports/FBgn0033264.html protein_coding_gene 0005515=protein binding "0007184=SMAD protein import into nucleus, 0006909=phagocytosis, 0022008=neurogenesis" 0005643=nuclear pore "Nup, nup50, Nup50, CG2158, Nuclear pore protein 50, Nucleoporin 50" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR015007=Nuclear pore complex, NUP2/50/61, IPR000156=Ran binding domain" CG2158 16-Dec-15 2015_12 ENSDARG00000017454(nup50) YLR335W(NUP2) WBGene00003802(npp-16) ENSXETG00000003053(nip50) "ENSMUSG00000016619(Nup50),ENSMUSG00000072878" ENSG00000093000(NUP50) "long lived,lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,trichogen cell,supernumerary,tormogen cell" FBgn0046661 anon-38C.43 anon-38C.43 http://flybase.net/reports/FBgn0046661.html gene 38C.43 16-Dec-15 2015_12 FBgn0265734 CR44541 http://flybase.net/reports/FBgn0265734.html non_protein_coding_gene CR44541 16-Dec-15 2015_12 FBgn0036327 CG10748 http://flybase.net/reports/FBgn0036327.html protein_coding_gene 0030060=L-malate dehydrogenase activity "0006099=tricarboxylic acid cycle, 0005975=carbohydrate metabolic process, 0006108=malate metabolic process" 0005759=mitochondrial matrix "IPR015955=Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR022383=Lactate/malate dehydrogenase, C-terminal, IPR010097=Malate dehydrogenase, type 1, IPR016040=NAD(P)-binding domain, IPR001557=L-lactate/malate dehydrogenase, IPR001252=Malate dehydrogenase, active site, IPR001236=Lactate/malate dehydrogenase, N-terminal" CG10748 16-Dec-15 2015_12 YKL085W(MDH1) viable FBgn0031066 COX6B Cytochrome c oxidase subunit 6B http://flybase.net/reports/FBgn0031066.html FBgn0064130 protein_coding_gene 0004129=cytochrome-c oxidase activity 0022008=neurogenesis 0005751=mitochondrial respiratory chain complex IV "CG14235, CcoVIb, COXG, Cytochrome c oxidase subunitVIb, Cytochrome c oxidase Polypeptide VIb, Cytochrome c oxidase subunit VIb, CoVIb, Cytochrome c oxidase polypeptide VIb, Cytochrome c oxidase VIb, Subunit VIb, VIb" "IPR003213=Cytochrome c oxidase, subunit VIb" CG14235 16-Dec-15 2015_12 "ENSDARG00000045230(zgc:92631),ENSDARG00000037860" YLR038C(COX12) WBGene00022170(Y71H2AM.5) ENSXETG00000017828(cox6b1) "ENSMUSG00000051811(Cox6b2),ENSMUSG00000036751(Cox6b1)" "ENSG00000126267(COX6B1),ENSG00000172912" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" DRSC27409 IK -1.673770547 -1.792033676 -0.553467068 -0.198414073 0.610369889 1.561194718 FBgn0031070 CG12702 http://flybase.net/reports/FBgn0031070.html protein_coding_gene lincRNA.1023 CG12702 16-Dec-15 2015_12 ENSMUSG00000033031(C330027C09Rik) ENSG00000163507(KIAA1524) viable FBgn0082579 zwi zwirbel http://flybase.net/reports/FBgn0082579.html gene 0010004=gastrulation involving germ band extension 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "mesoderm,presumptive embryonic/larval digestive system" FBgn0263353 CG11000 http://flybase.net/reports/FBgn0263353.html "FBgn0051555, FBgn0047238, FBgn0037380" protein_coding_gene "CG31555, BcDNA:HL04389" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG11000 16-Dec-15 2015_12 WBGene00009534(F38B7.3) FBgn0028743 Dhit Double hit http://flybase.net/reports/FBgn0028743.html protein_coding_gene "0005092=GDP-dissociation inhibitor activity, 0001965=G-protein alpha-subunit binding, 0005096=GTPase activator activity" "0008277=regulation of G-protein coupled receptor protein signaling pathway, 0038032=termination of G-protein coupled receptor signaling pathway" "0005886=plasma membrane, 0005737=cytoplasm" "EG:52C10.2, dhit, CG5036" "IPR024066=RGS, subdomain 1, IPR016137=RGS domain" CG5036 16-Dec-15 2015_12 ENSDARG00000038859(rgs20) "WBGene00004345(rgs-2),WBGene00004344(rgs-1)" ENSXETG00000008098(RGS20) "ENSMUSG00000019775(Rgs17),ENSMUSG00000002459(Rgs20)" "ENSG00000091844(RGS17),ENSG00000147509(RGS20)" wing margin bristle FBgn0262778 Su(E1)-L http://flybase.net/reports/FBgn0262778.html gene 16-Dec-15 2015_12 FBgn0004576 Pig2 Pre-intermoult gene 2 http://flybase.net/reports/FBgn0004576.html gene 0005198=structural molecule activity 0007594=puparial adhesion "pig2, Pig-2" 16-Dec-15 2015_12 FBgn0054008 CG34008 http://flybase.net/reports/FBgn0054008.html FBgn0082904 protein_coding_gene "unnamed, BP1002" CG34008 16-Dec-15 2015_12 FBgn0025471 qkr58E-6 quaking related 58E-6 http://flybase.net/reports/FBgn0025471.html gene qrk58E-6 16-Dec-15 2015_12 FBgn0026747 anon-25D26Aa anon-25D26Aa http://flybase.net/reports/FBgn0026747.html gene 16-Dec-15 2015_12 FBgn0015352 anon-99Ca anon-99Ca http://flybase.net/reports/FBgn0015352.html gene 16-Dec-15 2015_12 FBgn0067103 G6.A G6.A http://flybase.net/reports/FBgn0067103.html gene G6 16-Dec-15 2015_12 "visible,lethal,partially lethal - majority die" chaeta FBgn0265439 orb2::Mmus\Cpeb2 http://flybase.net/reports/FBgn0265439.html engineered_fusion_gene orb2[orb1RBD] 16-Dec-15 2015_12 "viable,learning defective,courtship behavior defective" FBgn0033169 CG11123 http://flybase.net/reports/FBgn0033169.html protein_coding_gene 0003723=RNA binding "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR001313=Pumilio RNA-binding repeat" CG11123 16-Dec-15 2015_12 YJL010C(NOP9) WBGene00014078(ZK792.5) ENSXETG00000008138(C14orf21) ENSMUSG00000019297(2610027L16Rik) ENSG00000196943(C14orf21) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0259242 CG42340 http://flybase.net/reports/FBgn0259242.html "FBgn0029872, FBgn0029871" protein_coding_gene 0005267=potassium channel activity 0071805=potassium ion transmembrane transport 0016020=membrane "CG12543, CG3367" "IPR003280=Two pore domain potassium channel, IPR013099=Potassium channel domain" CG42340 16-Dec-15 2015_12 DRSC18305 E -1.417026173 0.677930667 -0.240748222 1.581250051 -0.008698845 0.366282309 FBgn0016030 l(3)9D4 lethal (3) 9D4 http://flybase.net/reports/FBgn0016030.html gene 16-Dec-15 2015_12 lethal FBgn0260491 l(3)3425 http://flybase.net/reports/FBgn0260491.html gene "0048813=dendrite morphogenesis, 0007409=axonogenesis" 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,axon,dendrite" FBgn0025457 Bub3 Bub3 http://flybase.net/reports/FBgn0025457.html protein_coding_gene "0007052=mitotic spindle organization, 0007093=mitotic cell cycle checkpoint, 0007094=mitotic spindle assembly checkpoint" "0005654=nucleoplasm, 0005875=microtubule associated complex, 0000776=kinetochore" "BUB3, Dmbub3, bub3, dBUB3, CG7581" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat" CG7581 16-Dec-15 2015_12 WBGene00013209(bub-3) ENSXETG00000009564(BUB3) ENSMUSG00000066979(Bub3) ENSG00000154473(BUB3) " adult stage | male , larval stage " " spermatocyte

, neuroblast

" "viable,visible" trichogen cell FBgn0019883 anon-64Ea anon-64Ea http://flybase.net/reports/FBgn0019883.html gene unnamed 16-Dec-15 2015_12 FBgn0084551 Swg Swing http://flybase.net/reports/FBgn0084551.html gene 16-Dec-15 2015_12 "behavior defective,dominant,heat sensitive,neurophysiology defective,recessive" "indirect flight muscle,heat sensitive" FBgn0026616 ë±-Man-IIb ë±-Mannosidase class II b http://flybase.net/reports/FBgn0026616.html protein_coding_gene "0030246=carbohydrate binding, 0052767=mannosyl-oligosaccharide 1,6-alpha-mannosidase activity, 0008270=zinc ion binding, 0004572=mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity, 0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, 0004559=alpha-mannosidase activity" "0006517=protein deglycosylation, 0035010=encapsulation of foreign target, 0006491=N-glycan processing, 0006013=mannose metabolic process, 0016063=rhodopsin biosynthetic process" "0000139=Golgi membrane, 0012505=endomembrane system" "Golgi alpha-mannosidase IIb, alpha-M-II, alpha-Man-IIb, mannosidase II, CG4606, Man'ase, alpha-mannosidase, alpha-mannosidase-IIb, alpha-mannosidase 2, alpha Mannosidase IIb, alpha-Mannosidase class II b, DM-GII.2, alpha-Man-II b, alpha-D-mannosidase, GM, ManIIb, GTD#24/1" "IPR000602=Glycoside hydrolase family 38, N-terminal domain, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR015341=Glycoside hydrolase, family 38, central domain, IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR011013=Galactose mutarotase-like domain" CG4606 16-Dec-15 2015_12 "lethal,recessive,immune response defective,viable" FBgn0040532 CG8369 http://flybase.net/reports/FBgn0040532.html "FBgn0027745, FBgn0063255" protein_coding_gene 0048190=wing disc dorsal/ventral pattern formation "anon-EST:Posey161, BcDNA:GH11984" IPR002350=Kazal domain CG8369 16-Dec-15 2015_12 viable FBgn0025132 su(RpII140Z36)S15 su(RpII140Z36)S15 http://flybase.net/reports/FBgn0025132.html gene Z36[S15] 16-Dec-15 2015_12 FBgn0031980 RpL36A Ribosomal protein L36A http://flybase.net/reports/FBgn0031980.html FBgn0025270 protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0000022=mitotic spindle elongation" 0022625=cytosolic large ribosomal subunit "CG7424, anon-EST:fe1B2, anon-fast-evolving-1B2" "IPR011332=Zinc-binding ribosomal protein, IPR000552=Ribosomal protein L44e" CG7424 16-Dec-15 2015_12 ENSDARG00000058105(rpl36a) "YNL162W(RPL42A),YHR141C(RPL42B)" WBGene00004454(rpl-41) ENSXETG00000018150(rpl36a) "ENSMUSG00000049751(Rpl36al),ENSMUSG00000079435(Rpl36a),ENSMUSG00000078175(Gm6525)" ENSG00000165502(RPL36AL) lethal DRSC03055 IEK -1.798113552 -0.959610069 0.721300706 -3.360836949 0.408761397 4.045339765 FBgn0050488 antr antares http://flybase.net/reports/FBgn0050488.html protein_coding_gene "0032504=multicellular organism reproduction, 0046693=sperm storage, 0045434=negative regulation of female receptivity, post-mating" "0005615=extracellular space, 0005576=extracellular region" CG30488 "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG30488 16-Dec-15 2015_12 "mating behavior defective,female limited,female semi-fertile,viable" seminal receptacle FBgn0027585 CG8740 http://flybase.net/reports/FBgn0027585.html protein_coding_gene BcDNA:GH05582 CG8740 16-Dec-15 2015_12 "lethal,visible,planar polarity defective" trichogen cell FBgn0045979 PdL14B1 PdL14B1 http://flybase.net/reports/FBgn0045979.html gene unnamed 16-Dec-15 2015_12 "lethal,short lived,recessive" FBgn0259541 GG01233 http://flybase.net/reports/FBgn0259541.html gene 16-Dec-15 2015_12 visible wing FBgn0000325 clo close down http://flybase.net/reports/FBgn0000325.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile FBgn0001584 l(1)carot1 lethal (1) carot1 http://flybase.net/reports/FBgn0001584.html gene 16-Dec-15 2015_12 lethal FBgn0004387 Klp98A Kinesin-like protein at 98A http://flybase.net/reports/FBgn0004387.html protein_coding_gene "0005524=ATP binding, 0008017=microtubule binding, 0003777=microtubule motor activity, 1901981=phosphatidylinositol phosphate binding" "0045022=early endosome to late endosome transport, 0007018=microtubule-based movement" "0005871=kinesin complex, 0005768=endosome" "Klp98a, KLP6, CG5658, KIF16A/B, DmSNX23, Klp6, KIF 16A, DmKlp98A, KLP98A" "IPR019821=Kinesin motor domain, conserved site, IPR027640=Kinesin-like protein, IPR008984=SMAD/FHA domain, IPR001683=Phox homologous domain, IPR001752=Kinesin motor domain, IPR000253=Forkhead-associated (FHA) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG5658 16-Dec-15 2015_12 "ENSDARG00000010484(LOC570771),ENSDARG00000054448" ENSXETG00000003551(KIF16B) ENSMUSG00000038844(Kif16b) ENSG00000089177(KIF16B) viable FBgn0033802 CG17724 http://flybase.net/reports/FBgn0033802.html "FBgn0033804, FBgn0061358, FBgn0064120" protein_coding_gene "CG17724a, CG4037" CG17724 16-Dec-15 2015_12 "viable,fertile" FBgn0262275 mir-2280 mir-2280 stem loop http://flybase.net/reports/FBgn0262275.html miRNA_gene "dme-mir-2280, miR-2280, CR42982" CR42982 16-Dec-15 2015_12 viable FBgn0032511 ND-B22 NADH dehydrogenase (ubiquinone) B22 subunit http://flybase.net/reports/FBgn0032511.html protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "CG9306, NADH:ubiquinone oxidoreductase B22 subunit, NADH-ubiquinone oxidoreductase B22 subunit, NI2M, NADH ubiquinone oxidoreductase B22" CG9306 16-Dec-15 2015_12 ENSDARG00000041314(ndufb9) WBGene00015810(C16A3.5) ENSMUSG00000022354(Ndufb9) ENSG00000147684(NDUFB9) viable DRSC03193 K 0.471901099 -1.133314152 -1.079859272 0.820150589 1.603360279 -0.383777935 FBgn0030939 CG15041 http://flybase.net/reports/FBgn0030939.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011171 l(1)291-7 lethal (1) 291-7 http://flybase.net/reports/FBgn0011171.html FBgn0010199 gene 291-7 16-Dec-15 2015_12 "lethal,recessive" FBgn0266386 insc::pins http://flybase.net/reports/FBgn0266386.html engineered_fusion_gene insc::raps 16-Dec-15 2015_12 FBgn0038797 Dic2 Dicarboxylate carrier 2 http://flybase.net/reports/FBgn0038797.html protein_coding_gene "0022857=transmembrane transporter activity, 0015367=oxoglutarate:malate antiporter activity" "0006839=mitochondrial transport, 0055085=transmembrane transport" "0031966=mitochondrial membrane, 0005739=mitochondrion" "CG4323, DmDic2p" "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain, IPR002067=Mitochondrial carrier protein" CG4323 16-Dec-15 2015_12 ENSDARG00000025074(slc25a10) YLR348C(DIC1) ENSXETG00000019705(slc25a10) FBgn0065267 l(2)SH2067 lethal (2) SH2067 http://flybase.net/reports/FBgn0065267.html gene l(2)SH2 2067 16-Dec-15 2015_12 "lethal,recessive" FBgn0024321 NK7.1 NK7.1 http://flybase.net/reports/FBgn0024321.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG8524, Dm.HboxNK-7.1, NK-7.1" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR020479=Homeodomain, metazoa" CG8524 16-Dec-15 2015_12 WBGene00001096(dsc-1) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035428 CG14960 http://flybase.net/reports/FBgn0035428.html protein_coding_gene CG14960 16-Dec-15 2015_12 viable FBgn0025487 l(3)82Ea lethal (3) 82Ea http://flybase.net/reports/FBgn0025487.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0019761 l(1)72 lethal (1) 72 http://flybase.net/reports/FBgn0019761.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266525 CG45092 http://flybase.net/reports/FBgn0266525.html protein_coding_gene CG45092 16-Dec-15 2015_12 FBgn0028612 l(2)W13 lethal (2) W13 http://flybase.net/reports/FBgn0028612.html gene l(2R)W13 16-Dec-15 2015_12 "lethal,recessive" FBgn0041749 l(1)A106.1F1 lethal (1) A106.1F1 http://flybase.net/reports/FBgn0041749.html gene A106.1F1.L 16-Dec-15 2015_12 "lethal,recessive" FBgn0264086 CG43755 http://flybase.net/reports/FBgn0264086.html "FBgn0051920, FBgn0044566, FBgn0045216, FBgn0047313, FBgn0045202, FBgn0053992" protein_coding_gene "CG33992, BcDNA:GH10778, NEST:bs21f09, NEST:bs23f04, CG31920, anon-WO0140519.62" CG43755 16-Dec-15 2015_12 FBgn0265692 CR44499 http://flybase.net/reports/FBgn0265692.html non_protein_coding_gene lincRNA.956 CR44499 16-Dec-15 2015_12 FBgn0001783 l(1)M77 lethal (1) M77 http://flybase.net/reports/FBgn0001783.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011631 l(2)T57d13 lethal (2) T57d13 http://flybase.net/reports/FBgn0011631.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0002893 mus207 mutagen-sensitive 207 http://flybase.net/reports/FBgn0002893.html gene 0006302=double-strand break repair 16-Dec-15 2015_12 "DNA repair defective,chemical sensitive,radiation sensitive,recessive" FBgn0053475 CG33475 http://flybase.net/reports/FBgn0053475.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33475 16-Dec-15 2015_12 FBgn0001554 l(1)19Ad lethal (1) 19Ad http://flybase.net/reports/FBgn0001554.html gene 16-Dec-15 2015_12 lethal FBgn0264983 CR44134 http://flybase.net/reports/FBgn0264983.html non_protein_coding_gene CR44134 16-Dec-15 2015_12 FBgn0266728 CR45201 http://flybase.net/reports/FBgn0266728.html non_protein_coding_gene CR45201 16-Dec-15 2015_12 FBgn0266176 pre-mod(mdg4)-J http://flybase.net/reports/FBgn0266176.html protein_coding_gene CG44882 "IPR007588=Zinc finger, FLYWCH-type" CG44882 16-Dec-15 2015_12 FBgn0264617 CR43957 http://flybase.net/reports/FBgn0264617.html non_protein_coding_gene Mgn00541 CR43957 16-Dec-15 2015_12 FBgn0069115 mus215 mutagen-sensitive 215 http://flybase.net/reports/FBgn0069115.html gene 16-Dec-15 2015_12 "viable,chemical sensitive,female fertile,meiotic cell cycle defective,female" FBgn0065355 l(2)SH1767 lethal (2) SH1767 http://flybase.net/reports/FBgn0065355.html gene l(2)SH2 1767 16-Dec-15 2015_12 "lethal,recessive" FBgn0267697 CR46033 http://flybase.net/reports/FBgn0267697.html non_protein_coding_gene CR46033 16-Dec-15 2015_12 FBgn0052802 CG32802 http://flybase.net/reports/FBgn0052802.html protein_coding_gene 16-Dec-15 2015_12 DRSC25226 K -0.421410809 0.073822446 -0.85698047 0.148434421 -0.186454721 -1.596951708 FBgn0005214 l(3)ET5 lethal Elaine Tasaka 5 http://flybase.net/reports/FBgn0005214.html gene 16-Dec-15 2015_12 "lethal,cold sensitive,heat sensitive,male sterile" FBgn0035779 CG8562 http://flybase.net/reports/FBgn0035779.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis CT15463 "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A" CG8562 16-Dec-15 2015_12 viable FBgn0011596 fzo fuzzy onions http://flybase.net/reports/FBgn0011596.html "FBgn0044369, FBgn0044370, FBgn0044371" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0007005=mitochondrion organization, 0008053=mitochondrial fusion, 0030382=sperm mitochondrion organization, 0007287=Nebenkern assembly, 0007283=spermatogenesis" "0005740=mitochondrial envelope, 0016021=integral component of membrane, 0005886=plasma membrane, 0005741=mitochondrial outer membrane" "anon-WO0125274.25, anon-WO0125274.26, anon-WO0125274.1, CG4568" "IPR006884=Fzo/mitofusin HR2 domain, IPR030381=Dynamin-type guanine nucleotide-binding (G) domain, IPR027094=Mitofusin family, IPR027091=Transmembrane GTPase Fzo/Fzo1, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG4568 16-Dec-15 2015_12 "ENSDARG00000011884(LOC100329462),ENSDARG00000005121(mfn1)" YBR179C(FZO1) spermatogenesis && adult stage " Nebenkern

, spermatid

" "male sterile,recessive,viable,female fertile" "spermatid,Nebenkern,spermatid & mitochondrion,onion stage spermatid & mitochondrion,Nebenkern | germline clone,Nebenkern derivative" FBgn0263557 mir-4967 mir-4967 stem loop http://flybase.net/reports/FBgn0263557.html miRNA_gene "dme-mir-4967, CR43542" CR43542 16-Dec-15 2015_12 FBgn0263261 spa1 http://flybase.net/reports/FBgn0263261.html gene 0008406=gonad development sparse SGPs 1 16-Dec-15 2015_12 "gonad,gonadal sheath proper primordium" FBgn0038709 CG15025 http://flybase.net/reports/FBgn0038709.html protein_coding_gene CG15025 16-Dec-15 2015_12 viable FBgn0030851 CG8326 http://flybase.net/reports/FBgn0030851.html FBgn0043795 protein_coding_gene 0022008=neurogenesis BEST:LD29336 IPR026680=Coiled-coil domain-containing protein 137 CG8326 16-Dec-15 2015_12 ENSDARG00000038374(zgc:153477) ENSMUSG00000049957(Ccdc137) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0026302 anon-49Da anon-49Da http://flybase.net/reports/FBgn0026302.html gene cDNA3 16-Dec-15 2015_12 FBgn0054023 CG34023 http://flybase.net/reports/FBgn0054023.html FBgn0082834 protein_coding_gene "unnamed, BP1072" "IPR009003=Peptidase S1, PA clan" CG34023 16-Dec-15 2015_12 FBgn0086550 MRE19 mRNA-like ncRNA in embryogenesis 19 http://flybase.net/reports/FBgn0086550.html non_protein_coding_gene LD03248 16-Dec-15 2015_12 FBgn0000536 eas easily shocked http://flybase.net/reports/FBgn0000536.html "FBgn0043963, FBgn0044449" protein_coding_gene "0004305=ethanolamine kinase activity, 0004103=choline kinase activity" "0007638=mechanosensory behavior, 0007616=long-term memory, 0016310=phosphorylation, 0046959=habituation, 0009612=response to mechanical stimulus, 0016319=mushroom body development, 0007420=brain development, 0046337=phosphatidylethanolamine metabolic process, 0008306=associative learning, 0006646=phosphatidylethanolamine biosynthetic process, 0055059=asymmetric neuroblast division, 0001666=response to hypoxia" 0005737=cytoplasm "RE10142, ethanolamine kinase, PC80, EP770, CG3525, alpha lobes absent, unnamed, ala, alpha-lobe absent, RH11, Ethanolamine kinase, easily-shocked, EtnK" IPR011009=Protein kinase-like domain CG3525 16-Dec-15 2015_12 "ENSDARG00000019420(etnk1),ENSDARG00000070218,ENSDARG00000070213(etnk2)" WBGene00000515(ckc-1) "ENSMUSG00000030275(Etnk1),ENSMUSG00000070644(Etnk2)" "ENSG00000139163(ETNK1),ENSG00000143845(ETNK2)" "viable,behavior defective,recessive,fertile,neuroanatomy defective,lethal,wild-type,memory defective,mitotic cell cycle defective,bang sensitive,paralytic,neurophysiology defective,chemical conditional,drug conditional" "mushroom body alpha-lobe,mushroom body beta-lobe,adult mushroom body beta'-lobe,adult mushroom body alpha'-lobe,calyx of adult mushroom body,adult heart,mushroom body & neuron | somatic clone,adult heart ventral longitudinal muscle" FBgn0038321 CG6218 http://flybase.net/reports/FBgn0038321.html protein_coding_gene "IPR002731=ATPase, BadF/BadG/BcrA/BcrD type" CG6218 16-Dec-15 2015_12 ENSDARG00000059572(zgc:171682) WBGene00021057(W06B4.2) ENSXETG00000021541(NAGK) ENSMUSG00000034744(Nagk) ENSG00000124357(NAGK) "viable,fertile" DRSC15994 K -0.446154612 0.203588422 0.186444153 0.85682184 -1.100397164 1.719590348 FBgn0050365 spaw spacewatch http://flybase.net/reports/FBgn0050365.html "FBgn0033284, FBgn0065025" protein_coding_gene "BcDNA:AT04457, CG30365, spaw, CG2149, spacewatch" CG30365 16-Dec-15 2015_12 FBgn0036386 CG8833 http://flybase.net/reports/FBgn0036386.html protein_coding_gene 0003676=nucleic acid binding "0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" GPTC1 "IPR011666=Domain of unknown function DUF1604, IPR000467=G-patch domain" CG8833 16-Dec-15 2015_12 ENSDARG00000033418(gpatch1) WBGene00011109(R07E5.1) ENSXETG00000018276(gpatc1) ENSMUSG00000063808(Gpatch1) ENSG00000076650(GPATCH1) "partially lethal - majority die,some die during pupal stage" "germline cell,male" FBgn0035294 Mfap1 Microfibril-associated protein 1 http://flybase.net/reports/FBgn0035294.html protein_coding_gene 0005515=protein binding "0010389=regulation of G2/M transition of mitotic cell cycle, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" "0043234=protein complex, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0001527=microfibril" "microfibril-associated protein 1, CG1017, dmfap1" "IPR009730=Micro-fibrillar-associated protein 1, C-terminal" CG1017 16-Dec-15 2015_12 ENSDARG00000018241(mfap1) WBGene00009671(mfap-1) ENSXETG00000015470(mfap1) "ENSMUSG00000068479(Mfap1a),ENSMUSG00000048222(Mfap1b)" ENSG00000140259(MFAP1) "increased cell death,somatic clone,some die during larval stage,lethal - all die before end of larval stage,lethal,neuroanatomy defective" "wing disc,somatic clone,wing pouch,embryonic/larval neuroblast,ganglion mother cell" DRSC08154 I -0.341432633 1.621176125 -0.6308103 0.219067232 -0.832501431 -0.072645834 FBgn0021879 l(2)k13617 lethal (2) k13617 http://flybase.net/reports/FBgn0021879.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050499 CG30499 http://flybase.net/reports/FBgn0050499.html FBgn0033193 protein_coding_gene 0004750=ribulose-phosphate 3-epimerase activity "0005975=carbohydrate metabolic process, 0006098=pentose-phosphate shunt" CG1364 "IPR000056=Ribulose-phosphate 3-epimerase-like, IPR013785=Aldolase-type TIM barrel, IPR011060=Ribulose-phosphate binding barrel, IPR026019=Ribulose-phosphate 3-epimerase" CG30499 16-Dec-15 2015_12 "ENSDARG00000005251(rpe),ENSDARG00000069684" YJL121C(RPE1) WBGene00017272(F08F8.7) ENSXETG00000018617(RPE) ENSMUSG00000026005(Rpe) ENSG00000197713(RPE) "viable,fertile" FBgn0083983 mRpL34 mitochondrial ribosomal protein L34 http://flybase.net/reports/FBgn0083983.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0032543=mitochondrial translation" 0005762=mitochondrial large ribosomal subunit "Mitochondrial Ribosomal Protein L34, CG34147" IPR000271=Ribosomal protein L34 CG34147 16-Dec-15 2015_12 ENSG00000130312(MRPL34) lethal FBgn0262381 mir-276b mir-276b stem loop http://flybase.net/reports/FBgn0262381.html "FBgn0067716, FBgn0082179, FBgn0262197" miRNA_gene "dme-miR-276b, Mir-276b, miR-276, MiR-276b, miR-276b, CR42904, mir-276bS, dme-mir-276b, mir-276b, dme-mir-276, CR33586, CR33587" CR42904 16-Dec-15 2015_12 "visible,lethal,male limited" "wing,wing margin bristle,male limited" FBgn0052973 CG32973 http://flybase.net/reports/FBgn0052973.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053244 Ste:CG33244 Ste:CG33244 http://flybase.net/reports/FBgn0053244.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33244" "IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR000704=Casein kinase II, regulatory subunit" CG33244 16-Dec-15 2015_12 FBgn0011557 107.1 107.1 http://flybase.net/reports/FBgn0011557.html gene 16-Dec-15 2015_12 FBgn0045051 fs(1)242 female sterile (1) 242 http://flybase.net/reports/FBgn0045051.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "ovary,dorsal appendage" FBgn0085789 CR41506 http://flybase.net/reports/FBgn0085789.html FBan0041506 pseudogene_attribute CR41506 16-Dec-15 2015_12 FBgn0263938 BG00010 http://flybase.net/reports/FBgn0263938.html gene 16-Dec-15 2015_12 "long lived,male limited,starvation stress response defective,temperature response defective,female limited,locomotor behavior defective" FBgn0266558 EP3639 http://flybase.net/reports/FBgn0266558.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0025501 l(3)73Am lethal (3) 73Am http://flybase.net/reports/FBgn0025501.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263003 CG43311 http://flybase.net/reports/FBgn0263003.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053745 snmRNA:430:CR33745 snmRNA:430:CR33745 http://flybase.net/reports/FBgn0053745.html non_protein_coding_gene CR33745 CR33745 16-Dec-15 2015_12 FBgn0053410 5SrRNA:CR33410 5SrRNA:CR33410 http://flybase.net/reports/FBgn0053410.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33410 CR33410 16-Dec-15 2015_12 FBgn0028242 l(3)S001405 lethal (3) S001405 http://flybase.net/reports/FBgn0028242.html gene 0014/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0014384 sev::tor sev::tor http://flybase.net/reports/FBgn0014384.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 "visible,dominant" "mystery cell,primary pigment cell,cone cell,eye,ommatidium,photoreceptor cell R7" FBgn0019786 l(1)17 lethal (1) 17 http://flybase.net/reports/FBgn0019786.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032525 Hsp60D Hsp60D http://flybase.net/reports/FBgn0032525.html protein_coding_gene 0005524=ATP binding "0009408=response to heat, 0042026=protein refolding, 0006915=apoptotic process, 0006626=protein targeting to mitochondrion, 0006458='de novo' protein folding" 0005759=mitochondrial matrix CG16954 "IPR002423=Chaperonin Cpn60/TCP-1 family, IPR027409=GroEL-like apical domain, IPR027413=GroEL-like equatorial domain, IPR001844=Chaperonin Cpn60" CG16954 16-Dec-15 2015_12 "lethal,partially,visible,increased cell death,viable" "eye,eye disc" FBgn0027276 l(1)G0200 lethal (1) G0200 http://flybase.net/reports/FBgn0027276.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036921 RhoGDI RhoGDI http://flybase.net/reports/FBgn0036921.html protein_coding_gene 0005094=Rho GDP-dissociation inhibitor activity 0005737=cytoplasm CG7823 "IPR000406=Rho protein GDP-dissociation inhibitor, IPR014756=Immunoglobulin E-set, IPR024792=Rho GDP-dissociation inhibitor domain" CG7823 16-Dec-15 2015_12 "ENSDARG00000043795(arhgdia),ENSDARG00000004034(arhgdig)" YDL135C(RDI1) WBGene00004356(rhi-1) "ENSXETG00000025477(arhgdia),ENSXETG00000012139(arhgdig),ENSXETG00000002772(arhgdib)" "ENSMUSG00000025132(Arhgdia),ENSMUSG00000030220(Arhgdib),ENSMUSG00000073433(Arhgdig)" "ENSG00000141522(ARHGDIA),ENSG00000215642,ENSG00000111348(ARHGDIB),ENSG00000206156" "lethal,viable" FBgn0065499 l(2)SH1211 lethal (2) SH1211 http://flybase.net/reports/FBgn0065499.html gene l(2)SH2 1211 16-Dec-15 2015_12 "lethal,recessive" FBgn0264842 CR44050 http://flybase.net/reports/FBgn0264842.html non_protein_coding_gene CR44050 16-Dec-15 2015_12 FBgn0266378 CR45020 http://flybase.net/reports/FBgn0266378.html non_protein_coding_gene CR45020 16-Dec-15 2015_12 FBgn0011138 l(1)Q214 lethal (1) Q214 http://flybase.net/reports/FBgn0011138.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0034158 CG5522 http://flybase.net/reports/FBgn0034158.html protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0008321=Ral guanyl-nucleotide exchange factor activity" 0032485=regulation of Ral protein signal transduction "RasGPS, RalGPS" "IPR023578=Ras guanine nucleotide exchange factor domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR001849=Pleckstrin homology domain" CG5522 16-Dec-15 2015_12 "ENSDARG00000026519(ralgps2),ENSDARG00000068370(ralgps1)" ENSXETG00000021772() "ENSMUSG00000038831(Ralgps1),ENSMUSG00000026594(Ralgps2)" "ENSG00000136828(RALGPS1),ENSG00000116191(RALGPS2)" "viable,fertile" FBgn0026389 Or43a Odorant receptor 43a http://flybase.net/reports/FBgn0026389.html protein_coding_gene "0004984=olfactory receptor activity, 0004888=transmembrane signaling receptor activity, 0005549=odorant binding" "0051291=protein heterooligomerization, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "DOR43B.1, DOR87, AN14, Or43A, 43a, 43B1, or43a, Odorant receptor 87, Olfactory receptor 43B.1, DOR43a, Or, Dor87, Or43B.1, Or87, CG1854, OR43a, dor87, 43B.1" "IPR004117=Olfactory receptor, Drosophila" CG1854 16-Dec-15 2015_12 adult stage sensory neuron &&of antennal segment 3

"neurophysiology defective,viable" FBgn0052614 CG32614 http://flybase.net/reports/FBgn0052614.html protein_coding_gene 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0265003 koi klaroid http://flybase.net/reports/FBgn0265003.html "FBgn0033107, FBgn0028954, FBgn0033106" protein_coding_gene "0051647=nucleus localization, 0007097=nuclear migration" "0034993=LINC complex, 0034399=nuclear periphery, 0005639=integral component of nuclear inner membrane, 0048471=perinuclear region of cytoplasm, 0005637=nuclear inner membrane" "CG44154, BEST:LD11166, CG18584, Klaroid, CG3287, n(2)09967" "IPR012919=SUN domain, IPR018539=SUN domain-containing protein 1" CG44154 16-Dec-15 2015_12 FBgn0036991 CG5872 http://flybase.net/reports/FBgn0036991.html protein_coding_gene CG5872 16-Dec-15 2015_12 viable FBgn0034769 Obp58c Odorant-binding protein 58c http://flybase.net/reports/FBgn0034769.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp58c, AAF46892, CG13524" IPR006170=Pheromone/general odorant binding protein CG13524 16-Dec-15 2015_12 viable FBgn0052408 CG32408 http://flybase.net/reports/FBgn0052408.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029060 l(1)G0399 lethal (1) G0399 http://flybase.net/reports/FBgn0029060.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267871 CR46159 http://flybase.net/reports/FBgn0267871.html pseudogene_attribute CG12717-related CR46159 16-Dec-15 2015_12 FBgn0039233 CG7006 http://flybase.net/reports/FBgn0039233.html "FBgn0061419, FBgn0062030" protein_coding_gene 0003723=RNA binding "0040018=positive regulation of multicellular organism growth, 0042255=ribosome assembly" 0005634=nucleus "dNIP7, anon-WO0118547.410, BcDNA:GM12126" "IPR015947=PUA-like domain, IPR002478=PUA domain, IPR005155=Ribosome biogenesis factor NIP7-like, IPR016686=Ribosome biogenesis factor, NIP7" CG7006 16-Dec-15 2015_12 ENSDARG00000059075(nip7) YPL211W(NIP7) WBGene00016607(C43E11.9) ENSXETG00000017853(NIP7) ENSMUSG00000031917(Nip7) ENSG00000132603(NIP7) "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0051780 CG31780 http://flybase.net/reports/FBgn0051780.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG31780 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" FBgn0259349 C207 http://flybase.net/reports/FBgn0259349.html gene 16-Dec-15 2015_12 visible wing FBgn0002800 ms(1)16 male sterile (1) 16 http://flybase.net/reports/FBgn0002800.html gene 16-Dec-15 2015_12 "male sterile,female fertile,viable" "spermatid,spermatid axoneme,Nebenkern derivative,spermatozoon" FBgn0027228 l(1)G0298 lethal (1) G0298 http://flybase.net/reports/FBgn0027228.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0035496 CG14990 http://flybase.net/reports/FBgn0035496.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH97 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG14990 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" "viable,fertile" FBgn0005720 l(1)TK128 lethal (1) TK128 http://flybase.net/reports/FBgn0005720.html gene l128 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0065047 snoRNA:U3:54Ab snoRNA:U3:54Ab http://flybase.net/reports/FBgn0065047.html FBgn0053628 snoRNA_gene 0030556=rRNA modification guide activity 0005730=nucleolus "54A U3 snoRNA, U3 snoRNA, snoRNA U3, Dm-818, U3-snoRNA, CR33628" CR33628 16-Dec-15 2015_12 FBgn0035264 Oseg4 Outer segment 4 http://flybase.net/reports/FBgn0035264.html protein_coding_gene "0022008=neurogenesis, 0035058=nonmotile primary cilium assembly, 0042384=cilium assembly" "0031513=nonmotile primary cilium, 0030991=intraciliary transport particle A" "oseg4, OSEG, Wdr35, cytC40, Oseg4, WDR35, CG2069, OSEG4" "IPR017233=WD repeat protein 35, IPR001680=WD40 repeat, IPR011990=Tetratricopeptide-like helical domain, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG2069 16-Dec-15 2015_12 ENSDARG00000069269(si:ch211-206k20.4) WBGene00016935(ifta-1) ENSXETG00000008003(WDR35) ENSMUSG00000066643(Wdr35) ENSG00000118965(WDR35) "lethal,neuroanatomy defective,viable,partially lethal - majority die,recessive" ganglion mother cell FBgn0032039 CG13385 http://flybase.net/reports/FBgn0032039.html protein_coding_gene CG13385 16-Dec-15 2015_12 viable FBgn0033791 Drl-2 Derailed 2 http://flybase.net/reports/FBgn0033791.html FBgn0033790 protein_coding_gene "0005524=ATP binding, 0046982=protein heterodimerization activity, 0004713=protein tyrosine kinase activity" "0016055=Wnt signaling pathway, 0016201=synaptic target inhibition, 0007435=salivary gland morphogenesis, 0008045=motor neuron axon guidance, 0006468=protein phosphorylation" 0043235=receptor complex "drl-2, DNT-like, DRL-2, CG12463, CG3915, dnl, Derailed-2, doughnut-like, derailed-2" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR003306=WIF domain" CG3915 16-Dec-15 2015_12 WBGene00003007(lin-18) "viable,neuroanatomy defective" "presumptive embryonic salivary gland,antennal lobe,glomerulus,antennal lobe glomerulus VM7,antennal lobe glomerulus VL1" FBgn0001985 l(2)35De lethal (2) 35De http://flybase.net/reports/FBgn0001985.html FBgn0001988 gene "l(2)br46, l(2)35Dh, lethal(2)35Dh, br46, l35Dh" 16-Dec-15 2015_12 "visible,lethal,recessive" wing FBgn0261804 CG42750 http://flybase.net/reports/FBgn0261804.html "FBgn0051786, FBgn0032676, FBgn0259819, FBgn0051746, FBgn0032672, FBgn0032674, FBgn0032675, CG31746, CG15157" protein_coding_gene "0008235=metalloexopeptidase activity, 0008239=dipeptidyl-peptidase activity, 0016805=dipeptidase activity" 0006508=proteolysis "CG42400, CG31746, CG15158, CG7198, CG31786, CG15157, CG7167" "IPR008257=Renal dipeptidase family, IPR000180=Membrane dipeptidase, active site" CG42750 16-Dec-15 2015_12 FBgn0040816 CG12521 http://flybase.net/reports/FBgn0040816.html protein_coding_gene CG12521 16-Dec-15 2015_12 viable FBgn0004888 Scsë± Succinyl coenzyme A synthetase ë± subunit http://flybase.net/reports/FBgn0004888.html protein_coding_gene "0004776=succinate-CoA ligase (GDP-forming) activity, 0048037=cofactor binding" "0006099=tricarboxylic acid cycle, 0022008=neurogenesis" "0005739=mitochondrion, 0045244=succinate-CoA ligase complex (GDP-forming)" "scsalpha, succinyl-CoA synthetase alpha-subunit, CG1065, Succinyl coenzyme A synthatase, alpha subunit, Scs-alpha, Scsalpha, Succinyl coenzyme A synthetase alpha subunit" "IPR016102=Succinyl-CoA synthetase-like, IPR005811=ATP-citrate lyase/succinyl-CoA ligase, IPR016040=NAD(P)-binding domain, IPR003781=CoA-binding, IPR017440=ATP-citrate lyase/succinyl-CoA ligase, active site, IPR005810=Succinyl-CoA ligase, alpha subunit" CG1065 16-Dec-15 2015_12 ENSDARG00000052712(suclg1) YOR142W(LSC1) "WBGene00007350(C05G5.4),WBGene00017759(F23H11.3)" ENSXETG00000001690(suclg1) ENSMUSG00000052738(Suclg1) ENSG00000163541(SUCLG1) "viable,fertile,lethal,neuroanatomy defective,visible" "ganglion mother cell,trichogen cell" FBgn0037323 CG2663 http://flybase.net/reports/FBgn0037323.html protein_coding_gene "0008431=vitamin E binding, 0005215=transporter activity" 0006810=transport 0005622=intracellular alpha tocopherol transfer protein "IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG2663 16-Dec-15 2015_12 "viable,fertile" FBgn0060542 l(3)S099504 lethal (3) S099504 http://flybase.net/reports/FBgn0060542.html gene 0995/04 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0011182 l(1)294-16 lethal (1) 294-16 http://flybase.net/reports/FBgn0011182.html FBgn0010200 gene 294-16 16-Dec-15 2015_12 "lethal,recessive" FBgn0002159 l(2)pup lethal (2) pupal http://flybase.net/reports/FBgn0002159.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg" FBgn0037473 CG10068 http://flybase.net/reports/FBgn0037473.html protein_coding_gene 0005096=GTPase activator activity "0000281=mitotic cytokinesis, 0043547=positive regulation of GTPase activity, 0090175=regulation of establishment of planar polarity" "IPR006816=ELMO domain, IPR030724=ELMO domain-containing protein 2" CG10068 16-Dec-15 2015_12 ENSDARG00000052370(elmod2) ENSXETG00000014925(elmod2) "ENSMUSG00000035151(Elmod2),ENSMUSG00000041986(Elmod1)" "ENSG00000179387(ELMOD2),ENSG00000110675(ELMOD1)" viable "wing hair,supernumerary" FBgn0265161 CR44230 http://flybase.net/reports/FBgn0265161.html non_protein_coding_gene lincRNA.744 CR44230 16-Dec-15 2015_12 FBgn0264833 CR44041 http://flybase.net/reports/FBgn0264833.html non_protein_coding_gene CR44041 16-Dec-15 2015_12 FBgn0001025 fs(3)A16 female sterile (3) A16 http://flybase.net/reports/FBgn0001025.html gene 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oocyte" FBgn0262071 dlp::fz2 http://flybase.net/reports/FBgn0262071.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0034022 CG12964 http://flybase.net/reports/FBgn0034022.html protein_coding_gene CG12964 16-Dec-15 2015_12 viable FBgn0065758 l(2)SH0484 lethal (2) SH0484 http://flybase.net/reports/FBgn0065758.html gene l(2)SH2 0484 16-Dec-15 2015_12 "lethal,recessive" FBgn0066309 BPP.s BPP.s http://flybase.net/reports/FBgn0066309.html gene "BPPs, BPP" 16-Dec-15 2015_12 FBgn0037602 SLIRP2 SRA stem-loop interacting RNA binding protein 2 http://flybase.net/reports/FBgn0037602.html protein_coding_gene "0003676=nucleic acid binding, 0005515=protein binding, 0000166=nucleotide binding, 0003729=mRNA binding" 0046331=lateral inhibition 0035145=exon-exon junction complex "DmSLIRP2, CG8021, cg8021" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG8021 16-Dec-15 2015_12 ENSDARG00000041299(zgc:110796) "WBGene00011059(R06C1.4),WBGene00011155(R09B3.2),WBGene00011156(R09B3.3)" ENSXETG00000021349() ENSMUSG00000021040(1810035L17Rik) ENSG00000119705(SLIRP) "viable,visible" "chaeta,supernumerary,trichogen cell,wing" FBgn0022978 rrpC reduced receptor potential C http://flybase.net/reports/FBgn0022978.html gene 16-Dec-15 2015_12 FBgn0259896 NimC1 Nimrod C1 http://flybase.net/reports/FBgn0259896.html "FBgn0028545, FBgn0027847, FBgn0083073" protein_coding_gene "0006909=phagocytosis, 0042742=defense response to bacterium" "0005886=plasma membrane, 0016021=integral component of membrane" "Nimrod C1, BG:DS00180.10, nimrod C1, NimrodC1, nimrod, Nim, nimrodC1, P1, CT25688, NimC1, CG8942, nimC1, NimC" "IPR011489=EMI domain, IPR013032=EGF-like, conserved site, IPR000742=EGF-like domain, IPR009030=Insulin-like growth factor binding protein, N-terminal" CG8942 16-Dec-15 2015_12 ENSDARG00000039652(LOC100004638) "WBGene00018026(F35A5.4),WBGene00004104(pqn-13),WBGene00008559(F07H5.8)" ENSMUSG00000044476 FBgn0267646 CR45984 http://flybase.net/reports/FBgn0267646.html non_protein_coding_gene CR45984 16-Dec-15 2015_12 FBgn0000675 flp flipper http://flybase.net/reports/FBgn0000675.html gene 16-Dec-15 2015_12 "visible,sterile,body color defective,fertile" "wing,adult cuticle" FBgn0259288 EP-472 http://flybase.net/reports/FBgn0259288.html gene 16-Dec-15 2015_12 visible "wing,chaeta" FBgn0000401 cx curlex http://flybase.net/reports/FBgn0000401.html gene 16-Dec-15 2015_12 "visible,viable,reduced,male sterile,recessive" "wing,genitalia" FBgn0035334 CG8993 http://flybase.net/reports/FBgn0035334.html protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" "0006662=glycerol ether metabolic process, 0006974=cellular response to DNA damage stimulus, 0045454=cell redox homeostasis" 0005739=mitochondrion "thioredoxin, 8993" "IPR013766=Thioredoxin domain, IPR005746=Thioredoxin, IPR012336=Thioredoxin-like fold" CG8993 16-Dec-15 2015_12 ENSDARG00000034777(zgc:77127) WBGene00007099(trx-2) ENSXETG00000000246(txn2) ENSMUSG00000005354(Txn2) ENSG00000100348(TXN2) "viable,visible" trichogen cell FBgn0260328 GSd056 http://flybase.net/reports/FBgn0260328.html gene 16-Dec-15 2015_12 lethal FBgn0032973 CG6675 http://flybase.net/reports/FBgn0032973.html FBan0006675 protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0016298=lipase activity" 0016042=lipid catabolic process "IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family, IPR013818=Lipase, N-terminal" CG6675 16-Dec-15 2015_12 viable FBgn0032782 Rab9 Rab9 http://flybase.net/reports/FBgn0032782.html protein_coding_gene "0032403=protein complex binding, 0005525=GTP binding, 0003924=GTPase activity" "0042147=retrograde transport, endosome to Golgi, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport" "0031982=vesicle, 0055037=recycling endosome, 0005770=late endosome, 0005802=trans-Golgi network, 0045202=synapse, 0008021=synaptic vesicle, 0005769=early endosome" "146494_at, CG9994, DmRab9, rab9" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR003579=Small GTPase superfamily, Rab type" CG9994 16-Dec-15 2015_12 "ENSDARG00000045027(rab9a),ENSDARG00000062576(LOC100003363)" "ENSMUSG00000043463(Rab9b),ENSMUSG00000079316(Rab9)" viable "embryonic/larval dorsal trunk,mesothoracic tergum" FBgn0065235 l(2)SH2166 lethal (2) SH2166 http://flybase.net/reports/FBgn0065235.html gene l(2)SH2 2166 16-Dec-15 2015_12 "lethal,recessive" FBgn0053117 Victoria Victoria http://flybase.net/reports/FBgn0053117.html FBgn0032829 protein_coding_gene "0034644=cellular response to UV, 0009617=response to bacterium, 0034605=cellular response to heat" "0005615=extracellular space, 0005576=extracellular region" "CG33117, Turandot E, TotE, CG13963" IPR010825=Stress-inducible humoral factor Turandot CG33117 16-Dec-15 2015_12 FBgn0259949 Sfp23F Seminal fluid protein 23F http://flybase.net/reports/FBgn0259949.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0032504=multicellular organism reproduction, 0045861=negative regulation of proteolysis" 0005615=extracellular space "CG42459, Seminal fluid protein 23F" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42459 16-Dec-15 2015_12 FBgn0259469 C632 http://flybase.net/reports/FBgn0259469.html gene 16-Dec-15 2015_12 visible wing FBgn0036969 Spn77Bb Serpin 77Bb http://flybase.net/reports/FBgn0036969.html FBgn0036971 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "CG6266, Spn77, CG6663" "IPR023796=Serpin domain, IPR000215=Serpin family" CG6663 16-Dec-15 2015_12 "lethal,body color defective" mesothoracic tergum FBgn0069328 X-136-10 X-136-10 http://flybase.net/reports/FBgn0069328.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0033686 Hen1 http://flybase.net/reports/FBgn0033686.html protein_coding_gene "0008173=RNA methyltransferase activity, 0008171=O-methyltransferase activity" "0035194=posttranscriptional gene silencing by RNA, 0001510=RNA methylation" "PIMET, FBgn 33686, hen-1, Pimet, DmHen1, CG12367, hen1, Pimet/DmHen1, piRNA methyltransferase" "IPR026610=3'-RNA ribose 2'-O-methyltransferase, Hen1, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG12367 16-Dec-15 2015_12 ENSDARG00000018871(zgc:110175) WBGene00015349(C02F5.6) ENSMUSG00000045662(4921515J06Rik) "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0014992 l(2)47Aa lethal (2) 47Aa http://flybase.net/reports/FBgn0014992.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010323 Gsc Goosecoid http://flybase.net/reports/FBgn0010323.html "FBgn0004887, FBgn0008637, FBgn0010598" protein_coding_gene "0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0042803=protein homodimerization activity, 0046982=protein heterodimerization activity" "0006355=regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "l(2)05341, M72, D-Gsc, 60Mun1, CG2851, PPH25, gsc, Pph25, 60Mun2, Muenster 72, D-gsc, goosecoid" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG2851 16-Dec-15 2015_12 "ENSDARG00000017832,ENSDARG00000001859(dbx1b)" WBGene00006652(ttx-1) " embryonic stage | blastoderm , embryonic stage | stage 16 , embryonic stage | stage >=11 , embryonic stage , embryonic stage | stage >=10 " " procephalic neurogenic region

, embryonic stomatogastric nervous system

, stomodeum

, ring gland

, embryonic/larval foregut

, embryonic brain | restricted

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "stomatogastric nervous system,embryonic/larval foregut" FBgn0039744 CG15526 http://flybase.net/reports/FBgn0039744.html protein_coding_gene 0004540=ribonuclease activity 0008033=tRNA processing IPR002759=Ribonuclease P/MRP protein subunit CG15526 16-Dec-15 2015_12 "ENSDARG00000011152(rpp14),ENSDARG00000071574" ENSMUSG00000023156(Rpp14) ENSG00000163684(RPP14) viable DRSC15063 K -0.036205649 0.11048549 -1.163494847 0.450279742 -1.669813626 -0.947216445 FBgn0265552 l(3)KG06256 http://flybase.net/reports/FBgn0265552.html gene 16-Dec-15 2015_12 FBgn0083228 Frq2 Frequenin 2 http://flybase.net/reports/FBgn0083228.html FBgn0004120 protein_coding_gene 0005509=calcium ion binding "0007268=synaptic transmission, 0007528=neuromuscular junction development, 0016192=vesicle-mediated transport, 0046928=regulation of neurotransmitter secretion, 0007269=neurotransmitter secretion" 0008021=synaptic vesicle "frq2, frq, CG5907, Frq, unnamed, Frequenin, frequenin 2" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR028846=Recoverin family" CG5907 16-Dec-15 2015_12 "ENSDARG00000055229(ncs1a),ENSDARG00000054186(ncs1b)" YDR373W(FRQ1) WBGene00003563(ncs-1) ENSXETG00000001355(freq) ENSMUSG00000062661(Ncs1) ENSG00000107130(NCS1) "viable,fertile,neuroanatomy defective,neurophysiology defective,locomotor behavior defective" "type I bouton,embryonic/larval neuromuscular junction,NMJ bouton" FBgn0038204 CG14357 http://flybase.net/reports/FBgn0038204.html protein_coding_gene CG14357 16-Dec-15 2015_12 viable FBgn0065323 l(2)SH1912 lethal (2) SH1912 http://flybase.net/reports/FBgn0065323.html gene l(2)SH2 1912 16-Dec-15 2015_12 "lethal,recessive" FBgn0266871 CR45332 http://flybase.net/reports/FBgn0266871.html non_protein_coding_gene CR45332 16-Dec-15 2015_12 FBgn0263500 CR43489 http://flybase.net/reports/FBgn0263500.html non_protein_coding_gene lincRNA.801 CR43489 16-Dec-15 2015_12 FBgn0069403 KH2 KH2 http://flybase.net/reports/FBgn0069403.html gene 0016063=rhodopsin biosynthetic process 16-Dec-15 2015_12 FBgn0062623 Mod(var)1128 Mod(var)1128 http://flybase.net/reports/FBgn0062623.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1128 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0030839 CG5613 http://flybase.net/reports/FBgn0030839.html protein_coding_gene "0017022=myosin binding, 0033925=mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity" 0005737=cytoplasm "IPR005201=Glycoside hydrolase, family 85" CG5613 16-Dec-15 2015_12 WBGene00017164(eng-1) ENSXETG00000020214(ENGASE) ENSMUSG00000033857(Engase) ENSG00000167280(ENGASE) "viable,fertile" FBgn0260462 CG12163 http://flybase.net/reports/FBgn0260462.html "FBgn0037303, FBgn0046802, FBgn0062108" protein_coding_gene "0004869=cysteine-type endopeptidase inhibitor activity, 0004197=cysteine-type endopeptidase activity" "0035220=wing disc development, 0022416=chaeta development, 0035071=salivary gland cell autophagic cell death, 0006508=proteolysis, 0048102=autophagic cell death" "0098595=perivitelline space, 0045169=fusome" anon-WO0118547.305 "IPR013201=Cathepsin propeptide inhibitor domain (I29), IPR000169=Cysteine peptidase, cysteine active site, IPR000668=Peptidase C1A, papain C-terminal, IPR025661=Cysteine peptidase, asparagine active site, IPR013128=Peptidase C1A, IPR025660=Cysteine peptidase, histidine active site, IPR000010=Cystatin domain" CG12163 16-Dec-15 2015_12 viable FBgn0021585 DdbP2 Damage-specific DNA-binding protein 2 http://flybase.net/reports/FBgn0021585.html gene 0003684=damaged DNA binding 0005634=nucleus D-DDB P2 16-Dec-15 2015_12 FBgn0259526 B0511 http://flybase.net/reports/FBgn0259526.html gene 16-Dec-15 2015_12 visible wing FBgn0023051 l(1)3Al lethal (1) 3Al http://flybase.net/reports/FBgn0023051.html gene C2/5.6 16-Dec-15 2015_12 "lethal,recessive" FBgn0037442 godzilla godzilla E3 ubiquitin protein ligase http://flybase.net/reports/FBgn0037442.html protein_coding_gene "0061630=ubiquitin protein ligase activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0016197=endosomal transport" 0005768=endosome "godzilla, CG10277, godzilla[CG10277]" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR003137=PA domain, IPR001841=Zinc finger, RING-type" CG10277 16-Dec-15 2015_12 "ENSDARG00000019438(rnf13),ENSDARG00000017636(LOC100333827)" WBGene00007666(C18B12.4) "ENSXETG00000020089(rnf13),ENSXETG00000015314(RNF167)" "ENSMUSG00000036503(Rnf13),ENSMUSG00000040746(Rnf167)" "ENSG00000082996(RNF13),ENSG00000108523(RNF167)" viable "endosomeBx-MS1096,rhabdomere R7,endosomegodzillaëÓ1)" FBgn0039203 CG13618 http://flybase.net/reports/FBgn0039203.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG13618 16-Dec-15 2015_12 "viable,fertile" FBgn0086375 EP3377 http://flybase.net/reports/FBgn0086375.html gene 16-Dec-15 2015_12 FBgn0051126 CG31126 http://flybase.net/reports/FBgn0051126.html FBgn0039216 protein_coding_gene 0048812=neuron projection morphogenesis CG13621 IPR002634=BolA protein CG31126 16-Dec-15 2015_12 ENSDARG00000039915(zgc:101119) WBGene00019658(K11H12.1) ENSMUSG00000015943(Bola1) ENSG00000178096(BOLA1) viable FBgn0264391 CR43839 http://flybase.net/reports/FBgn0264391.html non_protein_coding_gene CR43839 16-Dec-15 2015_12 FBgn0267259 CR45695 http://flybase.net/reports/FBgn0267259.html non_protein_coding_gene CR45695 16-Dec-15 2015_12 FBgn0031776 CG13993 http://flybase.net/reports/FBgn0031776.html FBgn0027693 protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding 0016272=prefoldin complex anon-EST:Posey288 "IPR009053=Prefoldin, IPR002777=Prefoldin beta-like" CG13993 16-Dec-15 2015_12 ENSDARG00000014536(pfdn1) WBGene00007443(pfd-1) ENSXETG00000018313(PFDN1) ENSMUSG00000024346(Pfdn1) ENSG00000113068(PFDN1) viable embryonic/larval salivary gland FBgn0267653 CR45991 http://flybase.net/reports/FBgn0267653.html non_protein_coding_gene CR45991 16-Dec-15 2015_12 FBgn0034572 CG9346 http://flybase.net/reports/FBgn0034572.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003723=RNA binding" 0006396=RNA processing 0005654=nucleoplasm cg9346 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006569=CID domain, IPR000061=SWAP/Surp, IPR008942=ENTH/VHS, IPR000504=RNA recognition motif domain, IPR006903=RNA polymerase II-binding domain, IPR013170=mRNA splicing factor Cwf21 domain" CG9346 16-Dec-15 2015_12 ENSDARG00000061490(wu:fa03e02) WBGene00015581(C07H6.4) ENSXETG00000022133(SR140) ENSMUSG00000032407(2610101N10Rik) ENSG00000163714(U2SURP) viable FBgn0028946 Or35a Odorant receptor 35a http://flybase.net/reports/FBgn0028946.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "BG:BACR44L22.5, 35a, CG17868, OR35a, DOR91, 36E.1, BACR44L22.5" "IPR004117=Olfactory receptor, Drosophila" CG17868 16-Dec-15 2015_12 "neurophysiology defective,chemosensitive behavior defective,smell perception defective" olfactory sensory organ FBgn0001436 l(1)7Bd lethal (1) 7Bd http://flybase.net/reports/FBgn0001436.html gene "l(1)VA156, l(1)N63, l(1)RC21" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262750 Mst77Y-1 Male-specific transcript 77Y 1 http://flybase.net/reports/FBgn0262750.html nuclear_gene "0035093=spermatogenesis, exchange of chromosomal proteins" 0000785=chromatin 16-Dec-15 2015_12 FBgn0040519 CG15219 http://flybase.net/reports/FBgn0040519.html "FBan0015219, FBgn0063093" protein_coding_gene "BcDNA:LP09525, cg15219" CG15219 16-Dec-15 2015_12 viable DRSC03715 I -1.502898229 0.098089064 -0.321104769 0.773287686 0.230297516 -1.362630671 FBgn0019783 l(1)22 lethal (1) 22 http://flybase.net/reports/FBgn0019783.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022285 l(2)IR10 lethal (2) IR10 http://flybase.net/reports/FBgn0022285.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027590 GstE12 Glutathione S transferase E12 http://flybase.net/reports/FBgn0027590.html protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GSTE12, Glutathione transferase, gste12, CG16936, Glutathione S-transferase, BcDNA:GH04753, GST" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like" CG16936 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0260053 2L2416 http://flybase.net/reports/FBgn0260053.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0024626 l(2)k16616 lethal (2) k16616 http://flybase.net/reports/FBgn0024626.html gene 166/16 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0043022 snRNA:U5:38ABa snRNA:U5:38ABa http://flybase.net/reports/FBgn0043022.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "U5:38ABa, CR32881, U5 38ABa, 38A U5, U5-38ABa, K2, U5snRNA, small nuclear RNA U5, U5 snRNA, U5, U5var:38ABa, snRNA:U5, dU5, U5 small nuclear RNA" CR32881 16-Dec-15 2015_12 FBgn0031022 CG12204 http://flybase.net/reports/FBgn0031022.html protein_coding_gene CG12204 16-Dec-15 2015_12 viable FBgn0024759 EC70 EC70 http://flybase.net/reports/FBgn0024759.html gene 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation" FBgn0003694 thb thin bristle http://flybase.net/reports/FBgn0003694.html gene 16-Dec-15 2015_12 "visible,recessive,viable,female,reduced,female fertile" "macrochaeta,vibrissae,eye,wing vein L5,posterior crossvein" FBgn0029664 CG10802 http://flybase.net/reports/FBgn0029664.html FBgn0027766 protein_coding_gene "0003676=nucleic acid binding, 0004813=alanine-tRNA ligase activity, 0005524=ATP binding" 0006419=alanyl-tRNA aminoacylation anon-EST:Posey113 "IPR012947=Threonyl/alanyl tRNA synthetase, SAD, IPR009000=Translation protein, beta-barrel domain, IPR018163=Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR018164=Alanyl-tRNA synthetase, class IIc, N-terminal, IPR018165=Alanyl-tRNA synthetase, class IIc, core domain" CG10802 16-Dec-15 2015_12 ENSDARG00000015747(aarsd1) YNL040W() ENSXETG00000013644() ENSMUSG00000075528(1700113I22Rik) ENSG00000108825(AARSD1) "viable,visible" mesothoracic tergum FBgn0041596 l(2)PJ25 lethal (2) PJ25 http://flybase.net/reports/FBgn0041596.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052278 CG32278 http://flybase.net/reports/FBgn0052278.html FBgn0035408 protein_coding_gene CG12032 CG32278 16-Dec-15 2015_12 viable FBgn0030951 CG6873 http://flybase.net/reports/FBgn0030951.html protein_coding_gene 0003779=actin binding "0030042=actin filament depolymerization, 0022008=neurogenesis" 0015629=actin cytoskeleton "adf, cofilin homologue, Adf/cofilin-like" "IPR002108=Actin-depolymerising factor homology domain, IPR029006=ADF-H/Gelsolin-like domain, IPR017904=ADF/Cofilin/Destrin" CG6873 16-Dec-15 2015_12 "ENSDARG00000021124(cfl2l),ENSDARG00000014106(cfl2),ENSDARG00000012972(cfl1)" YLL050C(COF1) WBGene00006794(unc-60) "ENSXETG00000003016(BC091019.1),ENSXETG00000026161(cfl1),ENSXETG00000012301(cfl2)" "ENSMUSG00000015932(Dstn),ENSMUSG00000056201(Cfl1),ENSMUSG00000062929(Cfl2)" "ENSG00000172757(CFL1),ENSG00000165410(CFL2),ENSG00000125868(DSTN)" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026085 dgt4 dim ë_-tubulin 4 http://flybase.net/reports/FBgn0026085.html FBgn0062844 protein_coding_gene "0007088=regulation of mitotic nuclear division, 0007052=mitotic spindle organization" "0070652=HAUS complex, 0005819=spindle, 0005875=microtubule associated complex" "BcDNA:SD26403, mitotic spindle density 3, EG:EG0007.10, EG0007.10, CG4865, Dgt4, msd3" CG4865 16-Dec-15 2015_12 "viable,fertile" DRSC18659 I 2.256989241 1.348787123 0.236628882 0.218943915 -0.369896802 -0.98703201 FBgn0039395 CG14546 http://flybase.net/reports/FBgn0039395.html protein_coding_gene CG14546 16-Dec-15 2015_12 viable FBgn0060554 l(3)S097416 lethal (3) S097416 http://flybase.net/reports/FBgn0060554.html gene 0974/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0029177 EP1421 EP1421 http://flybase.net/reports/FBgn0029177.html gene "P277, EP(X)1421" 16-Dec-15 2015_12 FBgn0029849 Efr ER GDP-fucose transporter http://flybase.net/reports/FBgn0029849.html protein_coding_gene "0005460=UDP-glucose transmembrane transporter activity, 0005461=UDP-glucuronic acid transmembrane transporter activity, 0005464=UDP-xylose transmembrane transporter activity, 0005462=UDP-N-acetylglucosamine transmembrane transporter activity, 0005456=CMP-N-acetylneuraminate transmembrane transporter activity, 0005458=GDP-mannose transmembrane transporter activity, 0005457=GDP-fucose transmembrane transporter activity, 0005338=nucleotide-sugar transmembrane transporter activity" "0036066=protein O-linked fucosylation, 0015782=CMP-N-acetylneuraminate transport, 0015788=UDP-N-acetylglucosamine transport, 0015786=UDP-glucose transport, 0036084=GDP-fucose import into endoplasmic reticulum lumen, 0015790=UDP-xylose transport, 0015787=UDP-glucuronic acid transport, 0015784=GDP-mannose transport, 0055085=transmembrane transport, 0015783=GDP-fucose transport, 0015012=heparan sulfate proteoglycan biosynthetic process" "0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005794=Golgi apparatus" "ER GFP-fucose transporter, CG3774, Efr" IPR013657=UAA transporter CG3774 16-Dec-15 2015_12 "ENSDARG00000045382,ENSDARG00000071087(slc35b4),ENSDARG00000071079" YEL004W(YEA4) WBGene00017480(F15B10.1) ENSMUSG00000018999(Slc35b4) ENSG00000205060(SLC35B4) "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "wing vein L5,posterior crossvein" FBgn0041176 Ubx::Hmed\Lox4 Lox4 http://flybase.net/reports/FBgn0041176.html engineered_fusion_gene 16-Dec-15 2015_12 "leg,ectopic,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0259380 EP-450 http://flybase.net/reports/FBgn0259380.html gene 16-Dec-15 2015_12 visible "wing hair,wing" FBgn0004917 rls restless http://flybase.net/reports/FBgn0004917.html gene 16-Dec-15 2015_12 behavior defective FBgn0051239 CG31239 http://flybase.net/reports/FBgn0051239.html protein_coding_gene 16-Dec-15 2015_12 FBgn0067407 Or98P Odorant receptor 98a pseudogene http://flybase.net/reports/FBgn0067407.html FBgn0053345 pseudogene_attribute CR33345 CR33345 16-Dec-15 2015_12 DRSC22948 K 0.159327548 -0.158541804 -0.471928784 0.383432689 -0.130482054 1.615035794 FBgn0005434 l(1)v11 lethal (1) v11 http://flybase.net/reports/FBgn0005434.html gene l(1)11 16-Dec-15 2015_12 FBgn0024901 anon-a25 anon-a25 http://flybase.net/reports/FBgn0024901.html repeat_region a25 16-Dec-15 2015_12 FBgn0261373 CG33228 http://flybase.net/reports/FBgn0261373.html "FBgn0053228, FBgn0035048, FBgn0065735" protein_coding_gene "unnamed, l(2)SH2 0542, CG4806, lethal (2) SH0542, l(2)SH0542" CG33228 16-Dec-15 2015_12 "lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0028007 l(3)S115415 lethal (3) S115415 http://flybase.net/reports/FBgn0028007.html gene l(3)s036809 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0053773 CG33773 http://flybase.net/reports/FBgn0053773.html FBgn0082845 protein_coding_gene "unnamed, BP1061" IPR010512=Protein of unknown function DUF1091 CG33773 16-Dec-15 2015_12 FBgn0085535 CG40923 http://flybase.net/reports/FBgn0085535.html FBan0040923 protein_coding_gene 16-Dec-15 2015_12 FBgn0265511 CR44373 http://flybase.net/reports/FBgn0265511.html non_protein_coding_gene CR44373 16-Dec-15 2015_12 FBgn0040841 CG13286 http://flybase.net/reports/FBgn0040841.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065283 l(2)SH2024 lethal (2) SH2024 http://flybase.net/reports/FBgn0065283.html gene l(2)SH2 2024 16-Dec-15 2015_12 "lethal,recessive" FBgn0262817 CG43188 http://flybase.net/reports/FBgn0262817.html protein_coding_gene "MIP03057, noncoding_5956" CG43188 16-Dec-15 2015_12 FBgn0034402 CG15084 http://flybase.net/reports/FBgn0034402.html protein_coding_gene IPR007590=CWC16 protein CG15084 16-Dec-15 2015_12 ENSDARG00000041533(zgc:103496) WBGene00014250(ZK1307.9) ENSXETG00000025830(CCDC130) ENSMUSG00000004994(Ccdc130) ENSG00000104957(CCDC130) FBgn0031816 CG16947 http://flybase.net/reports/FBgn0031816.html FBgn0027732 protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination 0000151=ubiquitin ligase complex anon-EST:Posey20 "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR008913=Zinc finger, CHY-type, IPR004039=Rubredoxin-type fold, IPR001841=Zinc finger, RING-type, IPR017921=Zinc finger, CTCHY-type" CG16947 16-Dec-15 2015_12 ENSDARG00000016710(rchy1) ENSXETG00000000332(rchy1) ENSMUSG00000029397(Rchy1) ENSG00000163743(RCHY1) FBgn0015430 l(1)2BCb lethal (1) 2BCb http://flybase.net/reports/FBgn0015430.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263546 mir-4985 mir-4985 stem loop http://flybase.net/reports/FBgn0263546.html miRNA_gene "CR43531, dme-mir-4985" CR43531 16-Dec-15 2015_12 FBgn0033032 kune kune-kune http://flybase.net/reports/FBgn0033032.html protein_coding_gene "0019991=septate junction assembly, 0035159=regulation of tube length, open tracheal system, 0060857=establishment of glial blood-brain barrier" "0005918=septate junction, 0016021=integral component of membrane, 0005919=pleated septate junction" "kune-kune, CG1298, kune, Kune, Kune-kune" IPR004031=PMP-22/EMP/MP20/Claudin superfamily CG1298 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,embryonic/larval tracheal system" FBgn0043487 ins inseparabile http://flybase.net/reports/FBgn0043487.html gene 16-Dec-15 2015_12 FBgn0260616 2L3194 http://flybase.net/reports/FBgn0260616.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0069994 BG01856 BG01856 http://flybase.net/reports/FBgn0069994.html gene 16-Dec-15 2015_12 stress response defective FBgn0001466 l(1)7Fc lethal (1) 7Fc http://flybase.net/reports/FBgn0001466.html gene "JC18, l(1)GE208" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0011859 tRNA:G3:22BCa transfer RNA:gly3:22BCa http://flybase.net/reports/FBgn0011859.html "FBgn0003776, FBgn0051667, FBgn0060226" tRNA_gene "0033462=GGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Gly-GCC], phe-tRNA-2, CR31667, chr2L.trna40-GlyGCC, tRNA:gly3:22BCa, tRNA:G:GCC:AE002638-a, AE002638.trna7-GlyGCC" CR31667 16-Dec-15 2015_12 FBgn0261524 lic licorne http://flybase.net/reports/FBgn0261524.html "FBgn0015763, FBgn0024952, FBgn0027251, FBgn0024327" protein_coding_gene "0005524=ATP binding, 0031435=mitogen-activated protein kinase kinase kinase binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0004708=MAP kinase kinase activity" "0007179=transforming growth factor beta receptor signaling pathway, 0040018=positive regulation of multicellular organism growth, 0001934=positive regulation of protein phosphorylation, 0002385=mucosal immune response, 0006468=protein phosphorylation, 0045793=positive regulation of cell size, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0007314=oocyte anterior/posterior axis specification, 0007309=oocyte axis specification, 0000165=MAPK cascade, 0000187=activation of MAPK activity" 0005737=cytoplasm "DmMKK3, DMKK3, DMKK3/lic, Mkk3, DMEK3, Licorne, MEK-kinase 3, MEK3, Mpk3, MKK3, p38MAPKK, l(1)G0252, CG12244, dMKK3, Mek3, D-MKK3, MEK3/MKK3, p38, MAP kinase kinase 3, Drosophila MAP kinase kinase 3" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG12244 16-Dec-15 2015_12 YJL128C(PBS2) WBGene00004758(sek-1) ENSXETG00000022954(map2k6) "ENSMUSG00000018932(Map2k3),ENSMUSG00000020623(Map2k6)" "ENSG00000034152(MAP2K3),ENSG00000108984(MAP2K6)" " oogenesis stage | stage >=S10 && adult stage | female , embryonic stage , oogenesis stage | stage >=S7 && adult stage | female " " oocyte

, anterior embryonic/larval midgut

, nurse cell

, posterior embryonic/larval midgut

,

ubiquitous " FBgn0011483 l(3)neo50 lethal (3) neo50 http://flybase.net/reports/FBgn0011483.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003546 su(b) suppressor of black http://flybase.net/reports/FBgn0003546.html gene 16-Dec-15 2015_12 "chemical sensitive,fertile,reduced" FBgn0026226 l(1)16Fo lethal (1) 16Fo http://flybase.net/reports/FBgn0026226.html gene ME-VII 16-Dec-15 2015_12 lethal FBgn0017404 dode dorsal deviant http://flybase.net/reports/FBgn0017404.html gene 0007409=axonogenesis 16-Dec-15 2015_12 "chordotonal organ & axon | lateral,commissure,longitudinal connective" FBgn0035372 CG12093 http://flybase.net/reports/FBgn0035372.html protein_coding_gene IPR021454=Protein of unknown function DUF3105 CG12093 16-Dec-15 2015_12 WBGene00012755(Y41C4A.8) "viable,fertile,lethal" FBgn0036501 CG7272 http://flybase.net/reports/FBgn0036501.html protein_coding_gene "IPR018178=Putative SWEET transporter, Insecta" CG7272 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0028026 l(3)S103505b lethal (3) S103505b http://flybase.net/reports/FBgn0028026.html gene "1035/05, l(3)S103505" 16-Dec-15 2015_12 "lethal,recessive" FBgn0029887 CG3198 http://flybase.net/reports/FBgn0029887.html protein_coding_gene 0003729=mRNA binding "0006376=mRNA splice site selection, 0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction, 0000398=mRNA splicing, via spliceosome" 0005685=U1 snRNP IPR004882=Luc7-related CG3198 16-Dec-15 2015_12 "WBGene00016811(C50D2.8),WBGene00022489(Y119D3B.12)" ENSXETG00000011062(TGas054e13.1) DRSC18292 K 1.358112281 -0.065196479 0.946636305 -0.197617692 -1.873500318 -1.03340516 FBgn0038451 CG14893 http://flybase.net/reports/FBgn0038451.html protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity CT34717 "IPR016040=NAD(P)-binding domain, IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase" CG14893 16-Dec-15 2015_12 viable FBgn0083028 snoRNA:ë¬18S-525k snoRNA:ë¬18S-525k http://flybase.net/reports/FBgn0083028.html snoRNA_gene "psi18S-525k, CR34569" CR34569 16-Dec-15 2015_12 FBgn0032820 fbp "fructose-1,6-bisphosphatase" http://flybase.net/reports/FBgn0032820.html FBgn0051692 protein_coding_gene "0042132=fructose 1,6-bisphosphate 1-phosphatase activity" 0005975=carbohydrate metabolic process "FbPase, CG31692, CG10611" "IPR000146=Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase, IPR028343=Fructose-1,6-bisphosphatase, IPR020548=Fructose-1,6-bisphosphatase, active site" CG31692 16-Dec-15 2015_12 "ENSDARG00000012366(fbp2),ENSDARG00000021366(fbp1a),ENSDARG00000020364(erlin2)" YLR377C(FBP1) WBGene00001404(fbp-1) "ENSXETG00000017586(fbp2),ENSXETG00000017588(),ENSXETG00000028086(),ENSXETG00000028088()" "ENSMUSG00000069805(Fbp1),ENSMUSG00000021456(Fbp2)" "ENSG00000165140(FBP1),ENSG00000130957(FBP2)" "viable,fertile" FBgn0004696 vt verticals http://flybase.net/reports/FBgn0004696.html gene 16-Dec-15 2015_12 FBgn0050184 CG30184 http://flybase.net/reports/FBgn0050184.html protein_coding_gene CG30184 16-Dec-15 2015_12 "viable,fertile" FBgn0036790 AstC-R1 Allatostatin C receptor 1 http://flybase.net/reports/FBgn0036790.html "FBgn0044362, FBgn0046506, FBgn0046508" protein_coding_gene "0008188=neuropeptide receptor activity, 0008261=allatostatin receptor activity, 0004994=somatostatin receptor activity" "0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "Allatostatin C receptor 1, star1, Drostar1, ASC-receptor, anon-WO0131005.19, ASTC receptor 1, anon-WO0170980.80, allatostatin C receptor 1, Drosophila allatostatin C receptor 1, CG7285, ASTC-R1, anon-WO0170980.79" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000586=Somatostatin receptor family" CG7285 16-Dec-15 2015_12 "ENSDARG00000028785,ENSDARG00000067925(LOC557645),ENSDARG00000003049(sstr1),ENSDARG00000059090(LOC100333578),ENSDARG00000069806(LOC560530)" WBGene00020086(R106.2) "ENSXETG00000005731(SSTR5),ENSXETG00000009978(SSTR2),ENSXETG00000016039(SSTR3)" "ENSMUSG00000047904(Sstr2),ENSMUSG00000050824(Sstr5),ENSMUSG00000035431(Sstr1),ENSMUSG00000044933(Sstr3),ENSMUSG00000037014(Sstr4)" "ENSG00000180616(SSTR2),ENSG00000162009(SSTR5),ENSG00000183473(SSTR3),ENSG00000139874(SSTR1),ENSG00000132671(SSTR4)" " larval stage , adult stage " " larval central nervous system | restricted

, lamina & glial cell

, pars intercerebralis | restricted

, monopolar laminar cell

" viable FBgn0261090 Sytë_ Synaptotagmin ë_ http://flybase.net/reports/FBgn0261090.html "FBgn0036464, FBgn0040807, FBgn0259235, FBgn0084189, FBgn0261088, FBgn0044815" protein_coding_gene 0005544=calcium-dependent phospholipid binding "0007269=neurotransmitter secretion, 0016079=synaptic vesicle exocytosis" "0016020=membrane, 0016021=integral component of membrane, 0008021=synaptic vesicle" "Syt V, syt13, Syt beta, CG42333, Synaptotagmin beta, sytbeta, SytV, synaptotagmin beta, CG13462, Synaptotagmin V, dsytbeta, unnamed, SYT-beta, CG3020, Syt13" "IPR000008=C2 domain, IPR001565=Synaptotagmin, IPR028692=Synaptotagmin-13" CG42333 16-Dec-15 2015_12 DRSC10351 K 0.204901643 -0.404321491 -0.274063165 -0.54566193 -0.33602231 -1.537949104 FBgn0027944 prg piragua http://flybase.net/reports/FBgn0027944.html gene 0007391=dorsal closure pra 16-Dec-15 2015_12 FBgn0086286 GS1027 http://flybase.net/reports/FBgn0086286.html gene 1027 16-Dec-15 2015_12 FBgn0084042 CG41482 http://flybase.net/reports/FBgn0084042.html FBan0041482 protein_coding_gene 16-Dec-15 2015_12 FBgn0037443 Dmtn Dementin http://flybase.net/reports/FBgn0037443.html FBgn0062058 protein_coding_gene 0007420=brain development 0012505=endomembrane system "dmtn, CG1021, anon-WO0118547.375" IPR019394=Predicted transmembrane coiled-coil 2 protein CG1021 16-Dec-15 2015_12 "ENSDARG00000060954,ENSDARG00000046007(tmcc2)" WBGene00015800(C15H9.4) "ENSXETG00000000973(TMCC2),ENSXETG00000001473(TMCC1),ENSXETG00000023832(TMCC3)" "ENSMUSG00000042066(Tmcc2),ENSMUSG00000030126(Tmcc1),ENSMUSG00000020023(Tmcc3)" "ENSG00000133069(TMCC2),ENSG00000172765(TMCC1),ENSG00000057704(TMCC3)" "partially lethal - majority die,recessive,majority die during pupal stage,short lived,visible,neuroanatomy defective,viable" "wing,optic lobe,medulla neuropil" FBgn0039304 CG10425 http://flybase.net/reports/FBgn0039304.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain" CG10425 16-Dec-15 2015_12 ENSDARG00000012021(kdsr) ENSXETG00000024121(KDSR) ENSMUSG00000009905(Kdsr) ENSG00000119537(KDSR) viable FBgn0067648 sd-8 sd-8 http://flybase.net/reports/FBgn0067648.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 8 16-Dec-15 2015_12 "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0061125 l(3)S003601 lethal (3) S003601 http://flybase.net/reports/FBgn0061125.html gene 0036/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0039084 CG10175 http://flybase.net/reports/FBgn0039084.html protein_coding_gene 0052689=carboxylic ester hydrolase activity 0008152=metabolic process "IPR002168=Lipase, GDXG, active site, IPR029058=Alpha/Beta hydrolase fold, IPR019826=Carboxylesterase type B, active site, IPR002018=Carboxylesterase, type B" CG10175 16-Dec-15 2015_12 WBGene00019652(K11G9.1) "viable,fertile" FBgn0267014 CR45458 http://flybase.net/reports/FBgn0267014.html pseudogene_attribute CR45458 16-Dec-15 2015_12 FBgn0034120 CG15710 http://flybase.net/reports/FBgn0034120.html protein_coding_gene 0046872=metal ion binding "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG15710 16-Dec-15 2015_12 FBgn0034642 CG15674 http://flybase.net/reports/FBgn0034642.html protein_coding_gene CG15674 16-Dec-15 2015_12 "viable,fertile" FBgn0041602 g11 g11 http://flybase.net/reports/FBgn0041602.html gene 16-Dec-15 2015_12 FBgn0005258 l(3)SG78 lethal (3) SG78 http://flybase.net/reports/FBgn0005258.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082673 Fas1::sns Fas1::sns http://flybase.net/reports/FBgn0082673.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0261876 Z2-2317 http://flybase.net/reports/FBgn0261876.html gene 0030431=sleep 16-Dec-15 2015_12 behavior defective FBgn0085465 CG34436 http://flybase.net/reports/FBgn0085465.html "FBan0016918, FBgn0039574" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH201, CG16918" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG34436 16-Dec-15 2015_12 viable FBgn0032720 mRpL13 mitochondrial ribosomal protein L13 http://flybase.net/reports/FBgn0032720.html FBgn0025194 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005739=mitochondrion" "CG10603, anon-fast-evolving-3C4, anon-EST:fe3C4, CG10602, L13" "IPR023564=Ribosomal protein L13 domain, IPR005822=Ribosomal protein L13" CG10603 16-Dec-15 2015_12 ENSDARG00000056903(mrpl13) YOR150W(MRPL23) WBGene00008769(F13G3.11) ENSXETG00000025658(mrpl13) ENSMUSG00000022370(Mrpl13) ENSG00000172172(MRPL13) "viable,visible" trichogen cell FBgn0044106 E(rst)C408 E(rst)C408 http://flybase.net/reports/FBgn0044106.html gene 0001745=compound eye morphogenesis C408 16-Dec-15 2015_12 FBgn0022232 l(2)k03002a lethal (2) k03002a http://flybase.net/reports/FBgn0022232.html gene l(2)k03002 16-Dec-15 2015_12 "lethal,recessive" FBgn0043385 EP566a EP566a http://flybase.net/reports/FBgn0043385.html gene "EP0566a, Hypothetical protein 1" 16-Dec-15 2015_12 FBgn0036620 CG4842 http://flybase.net/reports/FBgn0036620.html protein_coding_gene 0004022=alcohol dehydrogenase (NAD) activity "0055114=oxidation-reduction process, 0048812=neuron projection morphogenesis" "IPR002424=Alcohol dehydrogenase, insect-type, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002426=Alcohol dehydrogenase, Ceratitis-type" CG4842 16-Dec-15 2015_12 "ENSDARG00000026236(zgc:56585),ENSDARG00000012016(LOC565975)" ENSXETG00000016904(hpgd) ENSMUSG00000031613(Hpgd) ENSG00000164120(HPGD) viable FBgn0014359 ms(3)HB737 ms(3)HB737 http://flybase.net/reports/FBgn0014359.html gene ms(2)HB737 16-Dec-15 2015_12 FBgn0034279 CG18635 http://flybase.net/reports/FBgn0034279.html protein_coding_gene IPR018629=Transport protein XK CG18635 16-Dec-15 2015_12 ENSXETG00000008109(Q4VV72_XENTR) ENSMUSG00000035067(Xkr6) ENSG00000171044(XKR6) viable FBgn0086065 snoRNA:Me28S-G3113a http://flybase.net/reports/FBgn0086065.html snoRNA_gene "Me-28S-G3113a(Dm3112), Me28S-Gm3113a, CR34694, Dm3112a" CR34694 16-Dec-15 2015_12 FBgn0003284 Rsp Responder to Sd http://flybase.net/reports/FBgn0003284.html repeat_region "rsp, Receptor-of-SD, Responder, Rsp-Sd, Director, Ac-SD, Activator of SD, Dr, Receptor" 16-Dec-15 2015_12 "viable,fertile" FBgn0070018 BG01047 BG01047 http://flybase.net/reports/FBgn0070018.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "stress response defective,viable,smell perception defective" FBgn0085579 CG41253 http://flybase.net/reports/FBgn0085579.html FBan0041253 protein_coding_gene 16-Dec-15 2015_12 FBgn0003020 ota7 olfactory trap abnormal 7 http://flybase.net/reports/FBgn0003020.html gene 0007635=chemosensory behavior olfactory-trap-abnormal-7 16-Dec-15 2015_12 "neurophysiology defective,recessive,smell perception defective,dominant,partially" FBgn0010043 GstD7 Glutathione S transferase D7 http://flybase.net/reports/FBgn0010043.html FBgn0038026 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "GSTD7, gstD26, CG4371, gstd7, Gst, DmGstd7, DmGST26, GstD26, Glutathione S transferase D26, DmGSTD7" "IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal" CG4371 16-Dec-15 2015_12 YNL229C(URE2) larval stage

"viable,visible" trichogen cell FBgn0277422 l(3)psg19 http://flybase.net/reports/FBgn0277422.html gene psg19 16-Dec-15 2015_12 FBgn0064142 shkl shackleton http://flybase.net/reports/FBgn0064142.html gene 0035191=nuclear axial expansion shakleton 16-Dec-15 2015_12 "pole cell,maternal effect,cleavage nucleus,centrosome & cleavage nucleus | maternal effect,germline clone" FBgn0014871 Pt1 Protein 1 http://flybase.net/reports/FBgn0014871.html gene 16-Dec-15 2015_12 FBgn0259176 bun bunched http://flybase.net/reports/FBgn0259176.html "FBgn0010460, FBgn0010670, FBgn0011724, FBgn0014385, FBgn0051857" protein_coding_gene "0042803=protein homodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0007476=imaginal disc-derived wing morphogenesis, 0007422=peripheral nervous system development, 0001751=compound eye photoreceptor cell differentiation, 0046843=dorsal appendage formation, 0030307=positive regulation of cell growth, 0007297=ovarian follicle cell migration, 0002052=positive regulation of neuroblast proliferation, 0042246=tissue regeneration, 0008284=positive regulation of cell proliferation, 0007304=chorion-containing eggshell formation, 0009996=negative regulation of cell fate specification, 0030707=ovarian follicle cell development, 0048749=compound eye development, 0006355=regulation of transcription, DNA-templated, 0045746=negative regulation of Notch signaling pathway, 0043066=negative regulation of apoptotic process, 0008101=decapentaplegic signaling pathway, 0035282=segmentation, 0048477=oogenesis, 0016319=mushroom body development, 0035071=salivary gland cell autophagic cell death, 0008340=determination of adult lifespan, 0001709=cell fate determination, 0048102=autophagic cell death" "0005634=nucleus, 0005829=cytosol, 0005737=cytoplasm" "Bun, EP(2)0488, bnc, 1550, l(2)k02903, BunA, CG31857, unnamed, short-sighted, shs, l(2)02687, Dm_2L:60722, CG5461, l(2)00255, Bunched, Tsc22, TSC-22, CG42281, short sighted, shortsighted, l(2)rI043, l(2)06475, l(2)05479" IPR000580=TSC-22 / Dip / Bun CG42281 16-Dec-15 2015_12 ENSXETG00000020092(TSC22D2) ENSMUSG00000027806(Tsc22d2) "ENSG00000196428(TSC22D2),ENSG00000102804(TSC22D1)" pupal stage salivary gland

larval stage | third instar eye-antennal disc

DRSC01255 E 0.822401203 1.070763877 1.561412756 0.428048882 -0.468112426 -0.556152458 FBgn0264347 CR43803 http://flybase.net/reports/FBgn0264347.html non_protein_coding_gene CR43803 16-Dec-15 2015_12 FBgn0042170 CG18850 http://flybase.net/reports/FBgn0042170.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030545 CG11590 http://flybase.net/reports/FBgn0030545.html FBgn0063185 protein_coding_gene 0010038=response to metal ion BcDNA:GM24986 "IPR004323=Divalent ion tolerance protein, CutA, IPR011322=Nitrogen regulatory PII-like, alpha/beta" CG11590 16-Dec-15 2015_12 ENSDARG00000054288(zgc:63972) ENSXETG00000025575(CUTA) ENSMUSG00000024194(Cuta) ENSG00000112514(CUTA) lethal FBgn0042119 Cpr65Au Cuticular protein 65Au http://flybase.net/reports/FBgn0042119.html FBgn0063231 protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr65Au, CG18778, BcDNA:GH21145" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG18778 16-Dec-15 2015_12 viable FBgn0267131 CR45571 http://flybase.net/reports/FBgn0267131.html non_protein_coding_gene CR45571 16-Dec-15 2015_12 FBgn0030682 CG12380 http://flybase.net/reports/FBgn0030682.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001001 fs(2)TLM female sterile (2) TLM http://flybase.net/reports/FBgn0001001.html gene 16-Dec-15 2015_12 "female sterile,recessive,male sterile" "ovary,ovariole,testis" FBgn0015980 l(2)PC4-F lethal (2) PC4-F http://flybase.net/reports/FBgn0015980.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010063 M(2)34k M(2)34k http://flybase.net/reports/FBgn0010063.html gene 16-Dec-15 2015_12 FBgn0262450 mir-312 mir-312 stem loop http://flybase.net/reports/FBgn0262450.html "FBgn0067692, FBgn0262310" miRNA_gene "0007391=dorsal closure, 0008258=head involution, 0071732=cellular response to nitric oxide" "CR33616, dme-miR-312, mir-312, mIR-312, 312, miR-312, mIR-310s, CR43017, dme-mir-312, Dme-miR-312" CR43017 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" "wing,wing hair,wing vein,sensillum campaniformium,ectopic,wing sensillum" FBgn0005736 l(1)TK223 lethal (1) TK223 http://flybase.net/reports/FBgn0005736.html gene l223 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0027187 l(2)60A-E lethal (2) 60A-E http://flybase.net/reports/FBgn0027187.html gene 16-Dec-15 2015_12 lethal FBgn0060304 l(3)S148907 lethal (3) S148907 http://flybase.net/reports/FBgn0060304.html gene 1489/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0259395 C67 http://flybase.net/reports/FBgn0259395.html gene 16-Dec-15 2015_12 visible "wing,chaeta,ectopic" FBgn0033268 Obp44a Odorant-binding protein 44a http://flybase.net/reports/FBgn0033268.html FBgn0026297 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "44a, DmelObp44a, anon-EST:ParkEST107, odorant-binding protein 44a, obp44a, CG2297, Obp44a, bs11e05.y1, Odorant-binding protein 44a" IPR006170=Pheromone/general odorant binding protein CG2297 16-Dec-15 2015_12 "viable,fertile" DRSC06838 K 1.363238525 0.049177845 -0.346613267 0.092470403 -0.705920768 2.261098541 FBgn0034753 CG2852 http://flybase.net/reports/FBgn0034753.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0000413=protein peptidyl-prolyl isomerization, 0032504=multicellular organism reproduction, 0006457=protein folding" "0005576=extracellular region, 0012505=endomembrane system, 0005811=lipid particle, 0005615=extracellular space, 0005875=microtubule associated complex" "IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000=Cyclophilin-like domain, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG2852 16-Dec-15 2015_12 ENSDARG00000052887(ppib) "YHR057C(CPR2),YDR304C(CPR5)" "WBGene00000881(cyn-5),WBGene00000882(cyn-6)" ENSXETG00000010651(TGas114p17.1) ENSMUSG00000032383(Ppib) ENSG00000166794(PPIB) viable FBgn0033732 CG13157 http://flybase.net/reports/FBgn0033732.html protein_coding_gene CG13157 16-Dec-15 2015_12 viable FBgn0027549 CG7927 http://flybase.net/reports/FBgn0027549.html FBgn0046458 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity 0000122=negative regulation of transcription from RNA polymerase II promoter 0005634=nucleus "BcDNA:GH11023, anon-WO0172774.138" IPR006994=Transcription factor 25 CG7927 16-Dec-15 2015_12 ENSDARG00000040861(tcf25) YDR333C() WBGene00010620(K07A12.1) ENSXETG00000023414(TCF25) ENSMUSG00000001472(Tcf25) ENSG00000141002(TCF25) viable FBgn0033060 CG7849 http://flybase.net/reports/FBgn0033060.html protein_coding_gene "0003723=RNA binding, 0009982=pseudouridine synthase activity" "0001522=pseudouridine synthesis, 0006396=RNA processing" "IPR002501=Pseudouridine synthase II, IPR020103=Pseudouridine synthase, catalytic domain" CG7849 16-Dec-15 2015_12 ENSDARG00000028379(zgc:91836) ENSXETG00000003973(trub2) ENSMUSG00000039826(Trub2) ENSG00000167112(TRUB2) "viable,visible" trichogen cell FBgn0019850 anon-XIV anon-XIV http://flybase.net/reports/FBgn0019850.html gene XIV 16-Dec-15 2015_12 FBgn0027647 l(2)dC9 lethal (2) dC9 http://flybase.net/reports/FBgn0027647.html gene P368 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003693 tha thin arched http://flybase.net/reports/FBgn0003693.html gene 16-Dec-15 2015_12 "visible,viable,male,poor,male fertile" "macrochaeta,wing" FBgn0004548 l(4)102CDt lethal (4) 102CDt http://flybase.net/reports/FBgn0004548.html gene l(4)35 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028055 l(3)S094603 lethal (3) S094603 http://flybase.net/reports/FBgn0028055.html gene 0946/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0043592 E(roDOM)3222 E(roDOM)3222 http://flybase.net/reports/FBgn0043592.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0028047 l(3)S096611 lethal (3) S096611 http://flybase.net/reports/FBgn0028047.html gene 0966/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0265862 CR44651 http://flybase.net/reports/FBgn0265862.html non_protein_coding_gene lincRNA.365 CR44651 16-Dec-15 2015_12 FBgn0037129 CG14565 http://flybase.net/reports/FBgn0037129.html protein_coding_gene CG14565 16-Dec-15 2015_12 "viable,fertile" FBgn0022293 l(1)M95.1 lethal (1) M95.1 http://flybase.net/reports/FBgn0022293.html gene M95.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0010638 Sec61ë_ Sec61 ë_ subunit http://flybase.net/reports/FBgn0010638.html FBgn0033947 protein_coding_gene 0008565=protein transporter activity "0006616=SRP-dependent cotranslational protein targeting to membrane, translocation, 0048812=neuron projection morphogenesis, 0010507=negative regulation of autophagy" "0012505=endomembrane system, 0005784=Sec61 translocon complex" "Sec1, sec61beta, CG10130, DSec61beta, Sec61, l(2)07214, Sec61beta, Secbeta61, sec61b" "IPR016482=Protein transport protein SecG/Sec61-beta/Sbh, IPR030671=Protein transport Sec61-beta/Sbh" CG10130 16-Dec-15 2015_12 "YER087C-B(SBH1),YER019C-A(SBH2)" WBGene00021427(Y38F2AR.9) ENSXETG00000027356(SEC61B) "ENSMUSG00000053317(Sec61b),ENSMUSG00000067657" ENSG00000106803(SEC61B) "lethal,recessive,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,wild-type" "dorsal appendage,egg,chorion,embryonic/first instar larval cuticle,leg,germline clone,head,abdomen,posterior,denticle belt,epicuticle,endocuticle,embryonic/larval trachea,eye,somatic clone,ommatidium,rhabdomere,tarsal segment,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0032635 CG15141 http://flybase.net/reports/FBgn0032635.html FBgn0046264 protein_coding_gene 0008270=zinc ion binding BEST:LD24839 "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR003126=Zinc finger, UBR-type" CG15141 16-Dec-15 2015_12 ENSDARG00000005536(ubr7) WBGene00011912(T22C1.1) ENSXETG00000010305(UBR7) ENSMUSG00000041712(Ubr7) ENSG00000012963(UBR7) viable FBgn0050442 CG30442 http://flybase.net/reports/FBgn0050442.html "FBgn0046100, FBgn0063726" protein_coding_gene "BcDNA:AT17684, NEST:bs03e05" IPR009882=Gypsy 16-Dec-15 2015_12 FBgn0267826 CR46147 http://flybase.net/reports/FBgn0267826.html non_protein_coding_gene CR46147 16-Dec-15 2015_12 FBgn0027529 CG8920 http://flybase.net/reports/FBgn0027529.html protein_coding_gene BcDNA:LD21403 "IPR002999=Tudor domain, IPR025605=OST-HTH/LOTUS domain" CG8920 16-Dec-15 2015_12 "ENSDARG00000032808(tdrd7),ENSDARG00000052095(LOC100004703)" ENSXETG00000010171(Q5M7P8_XENTR) ENSMUSG00000035517(Tdrd7) ENSG00000196116(TDRD7) "viable,fertile" FBgn0017380 l(1)7-103 lethal (1) 7-103 http://flybase.net/reports/FBgn0017380.html gene 7-103 16-Dec-15 2015_12 "lethal,recessive" FBgn0030520 Pdcd4 Programmed cell death 4 ortholog http://flybase.net/reports/FBgn0030520.html protein_coding_gene "2000738=positive regulation of stem cell differentiation, 0030727=germarium-derived female germ-line cyst formation" 0005829=cytosol "CG10990, Programmed cell death 4" "IPR016024=Armadillo-type fold, IPR016021=MIF4G-like domain, IPR003891=Initiation factor eIF-4 gamma, MA3" CG10990 16-Dec-15 2015_12 "ENSDARG00000041022(pdcd4b),ENSDARG00000021702(pdcd4a)" ENSXETG00000025248(pdcd4) ENSMUSG00000024975(Pdcd4) ENSG00000150593(PDCD4) "viable,female fertile,male fertile,long lived,starvation stress response defective,female limited,temperature response defective,locomotor behavior defective" germarium FBgn0267645 CR45983 http://flybase.net/reports/FBgn0267645.html non_protein_coding_gene CR45983 16-Dec-15 2015_12 FBgn0263568 mir-4946 mir-4946 stem loop http://flybase.net/reports/FBgn0263568.html miRNA_gene "dme-mir-4946, CR43553" CR43553 16-Dec-15 2015_12 FBgn0260018 diplomatico diplomatico http://flybase.net/reports/FBgn0260018.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0082929 snoRNA:Me28S-G2703c snoRNA:Me28S-G2703c http://flybase.net/reports/FBgn0082929.html snoRNA_gene "CR34541, Me28S-Gm2703c, Me28S-G2703, Me28S-G2703c" CR34541 16-Dec-15 2015_12 FBgn0014854 htl::tor htl::tor http://flybase.net/reports/FBgn0014854.html engineered_fusion_gene Fr1::tor 16-Dec-15 2015_12 visible "wing,wing vein,ectopic,wing cell" FBgn0263475 snoRNA:CG16892-a http://flybase.net/reports/FBgn0263475.html snoRNA_gene CR43590 16-Dec-15 2015_12 FBgn0036237 viaf viral IAP-associated factor http://flybase.net/reports/FBgn0036237.html "FBgn0044799, FBgn0044800" protein_coding_gene 0043281=regulation of cysteine-type endopeptidase activity involved in apoptotic process 0005737=cytoplasm "anon-WO0134798.18, viaf1, VIAF, anon-WO0134798.17, CG18593" "IPR024253=Phosducin, thioredoxin-like domain, IPR012336=Thioredoxin-like fold" CG18593 16-Dec-15 2015_12 YOR281C(PLP2) ENSXETG00000021779(pdcl3) "ENSMUSG00000026078(Pdcl3),ENSMUSG00000029235(Pdcl2)" "ENSG00000115539(PDCL3),ENSG00000163440(PDCL2)" FBgn0265608 CG44426 http://flybase.net/reports/FBgn0265608.html protein_coding_gene lincRNA.1032 CG44426 16-Dec-15 2015_12 FBgn0067373 l(2)NC139 lethal (2) NC139 http://flybase.net/reports/FBgn0067373.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024291 Sirt1 Sirtuin 1 http://flybase.net/reports/FBgn0024291.html FBgn0046250 protein_coding_gene "0004407=histone deacetylase activity, 0017136=NAD-dependent histone deacetylase activity, 0070403=NAD+ binding, 0008134=transcription factor binding" "0008340=determination of adult lifespan, 0007584=response to nutrient, 2000253=positive regulation of feeding behavior, 0048149=behavioral response to ethanol, 0016575=histone deacetylation, 0042981=regulation of apoptotic process, 0006342=chromatin silencing, 0006355=regulation of transcription, DNA-templated, 0035065=regulation of histone acetylation" "0005654=nucleoplasm, 0005634=nucleus, 0005737=cytoplasm" "dsir2, CG5216, dSir2, Silent information regulator 2, sir2, DSir2, BEST:LD38188, l(2)05326, dmSRT406, D.mel1, Sir2, SIR2, Sir2L, dSIR2" "IPR026590=Sirtuin family, catalytic core domain, IPR026591=Sirtuin family, catalytic core small domain, IPR003000=Sirtuin family, IPR029035=DHS-like NAD/FAD-binding domain" CG5216 16-Dec-15 2015_12 ENSDARG00000039684(sirt5) YOR025W(HST3) ENSXETG00000023588(sirt1) ENSMUSG00000020063(Sirt1) ENSG00000096717(SIRT1) "lethal - all die before end of embryonic stage,some die during embryonic stage,short lived,long lived,male limited,female limited,viable,RU486 conditional,suppressor of variegation,dominant,non-suppressor of variegation,male,female,fertile,hypoactive,conditional,chemical resistant,enhancer of variegation,feeding behavior defective,visible,eye color defective,increased cell death,lethal,partially lethal - majority die,some die during pupal stage" "chromatinda.G32,nucleolusda.G32,eye,eye disc | third instar larval stage,wing" FBgn0085220 CG34191 http://flybase.net/reports/FBgn0085220.html protein_coding_gene "IPR029071=Ubiquitin-related domain, IPR005375=Ubiquitin-fold modifier 1" CG34191 16-Dec-15 2015_12 ENSDARG00000043857(ufm1) WBGene00044324(tag-277) ENSXETG00000027207(UFM1) ENSMUSG00000027746(Ufm1) ENSG00000120686(UFM1) FBgn0020326 anon-72Ea anon-72Ea http://flybase.net/reports/FBgn0020326.html gene "unnamed, 4A11" 16-Dec-15 2015_12 FBgn0014851 Eig71Ek Eig71Ek http://flybase.net/reports/FBgn0014851.html protein_coding_gene "0042742=defense response to bacterium, 0007552=metamorphosis" 0005576=extracellular region "L71-11, L71, EIG71-K, CG7325" IPR003475=Insect protein of unknown function CG7325 16-Dec-15 2015_12 FBgn0265641 CR44448 http://flybase.net/reports/FBgn0265641.html non_protein_coding_gene CR44448 16-Dec-15 2015_12 FBgn0037327 PEK pancreatic eIF-2ë± kinase http://flybase.net/reports/FBgn0037327.html FBgn0041196 protein_coding_gene "0004686=elongation factor-2 kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0017148=negative regulation of translation, 0010508=positive regulation of autophagy, 0006986=response to unfolded protein, 0006983=ER overload response, 0010389=regulation of G2/M transition of mitotic cell cycle" "0005788=endoplasmic reticulum lumen, 0005783=endoplasmic reticulum" "DpERK, PERK, pancreatic eIF2alpha kinase, pERK, perk, CG2087, DmPEK, Pek, DPERK, EIF2-like, pek, Perk, dPERK, PEK" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR027295=Quinonprotein alcohol dehydrogenase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR018391=Pyrrolo-quinoline quinone beta-propeller repeat, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG2087 16-Dec-15 2015_12 WBGene00003970(pek-1) ENSXETG00000001926(EIF2AK3) ENSMUSG00000031668(Eif2ak3) ENSG00000172071(EIF2AK3) "viable,fertile,mitotic cell cycle defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,conditional" "eye,temperature conditional,eye disc,eye disc posterior to the morphogenetic furrow,conditional" DRSC12361 E -0.196470071 0.339484588 -0.320764194 1.645681995 -0.288232431 0.511247855 FBgn0033582 CG9084 http://flybase.net/reports/FBgn0033582.html protein_coding_gene IPR005552=Scramblase CG9084 16-Dec-15 2015_12 YJR100C(AIM25) viable FBgn0036876 CG9451 http://flybase.net/reports/FBgn0036876.html protein_coding_gene 0003993=acid phosphatase activity 0016311=dephosphorylation "0005634=nucleus, 0070062=extracellular exosome" "IPR000560=Histidine phosphatase superfamily, clade-2, IPR029630=Venom acid phosphatase Acph-1, IPR029033=Histidine phosphatase superfamily" CG9451 16-Dec-15 2015_12 viable FBgn0014912 anon-4Ff anon-4Ff http://flybase.net/reports/FBgn0014912.html gene 16-Dec-15 2015_12 FBgn0030757 CG9902 http://flybase.net/reports/FBgn0030757.html protein_coding_gene CG9902 16-Dec-15 2015_12 viable FBgn0266740 CR45213 http://flybase.net/reports/FBgn0266740.html non_protein_coding_gene CR45213 16-Dec-15 2015_12 FBgn0266193 ftz-f1::smt3 http://flybase.net/reports/FBgn0266193.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0082682 E(ftz)3150 E(ftz)3150 http://flybase.net/reports/FBgn0082682.html gene 3150 16-Dec-15 2015_12 FBgn0087008 e(y)3 enhancer of yellow 3 http://flybase.net/reports/FBgn0087008.html "FBgn0000619, FBgn0027204, FBgn0027235, FBgn0027245, FBgn0028301, FBgn0031046, FBgn0026680" protein_coding_gene "0003682=chromatin binding, 0008270=zinc ion binding" "0045893=positive regulation of transcription, DNA-templated, 0048477=oogenesis, 0046427=positive regulation of JAK-STAT cascade, 0007480=imaginal disc-derived leg morphogenesis, 0045892=negative regulation of transcription, DNA-templated, 0016458=gene silencing, 0031936=negative regulation of chromatin silencing" "0005634=nucleus, 0070604=PBAF complex, 0005700=polytene chromosome, 0000792=heterochromatin, 0000791=euchromatin" "SAYP, l(1)G0266, supporter of activation of yellow protein, lethal (1) G0084, l(1)G0084, Supporter of Activation of Yellow Protein, CG12238, l(1)G0283, l(1)G0409, sayp, e(y)[3], l(1)G0381" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR019787=Zinc finger, PHD-finger, IPR001965=Zinc finger, PHD-type" CG12238 16-Dec-15 2015_12 DRSC19450 E -0.421212157 -0.357969731 1.354483158 -2.69363077 -1.410273557 -1.483712065 FBgn0032251 Nse4 Non-SMC element 4 http://flybase.net/reports/FBgn0032251.html protein_coding_gene 0019789=SUMO transferase activity 0006281=DNA repair "0005634=nucleus, 0030915=Smc5-Smc6 complex" "CG13142, Nse4" "IPR014854=Non-structural maintenance of chromosome element 4, C-terminal, IPR027786=Nse4/EID family" CG13142 16-Dec-15 2015_12 YDL105W(NSE4) WBGene00010409(H21P03.2) ENSXETG00000015589(NSMCE4A) ENSMUSG00000040331(Nsmce4a) viable FBgn0265418 CR44330 http://flybase.net/reports/FBgn0265418.html non_protein_coding_gene CR44330 16-Dec-15 2015_12 FBgn0085227 CG34198 http://flybase.net/reports/FBgn0085227.html protein_coding_gene CG34198 16-Dec-15 2015_12 FBgn0259858 Su(Ste):CR42427 Su(Ste):CR42427 http://flybase.net/reports/FBgn0259858.html non_protein_coding_gene CR42427 CR42427 16-Dec-15 2015_12 FBgn0002990 olfA olfactory A http://flybase.net/reports/FBgn0002990.html gene olfactory-A 16-Dec-15 2015_12 "smell perception defective,recessive,viable,fertile" FBgn0011113 l(1)Q74 lethal (1) Q74 http://flybase.net/reports/FBgn0011113.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0060679 l(3)S076903 lethal (3) S076903 http://flybase.net/reports/FBgn0060679.html gene 0769/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0002818 ms(2)2R male sterile (2) 2R http://flybase.net/reports/FBgn0002818.html gene 16-Dec-15 2015_12 male sterile FBgn0010511 l(2)02321 lethal (2) 02321 http://flybase.net/reports/FBgn0010511.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267630 CR45968 http://flybase.net/reports/FBgn0267630.html non_protein_coding_gene CR45968 16-Dec-15 2015_12 FBgn0067742 l(1)G0288 lethal (1) G0288 http://flybase.net/reports/FBgn0067742.html gene 16-Dec-15 2015_12 lethal FBgn0035849 ERR estrogen-related receptor http://flybase.net/reports/FBgn0035849.html protein_coding_gene "0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0008270=zinc ion binding, 0003707=steroid hormone receptor activity, 0005496=steroid binding" "0005975=carbohydrate metabolic process, 0043401=steroid hormone mediated signaling pathway, 0007283=spermatogenesis, 0006357=regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "NR3B4, CG7404, estrogen related receptor, Estrogen-Related Receptor, dERR" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR027289=Oestrogen-related receptor, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR024178=Oestrogen receptor/oestrogen-related receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR001723=Nuclear hormone receptor" CG7404 16-Dec-15 2015_12 "ENSDARG00000069266(esrra),ENSDARG00000004861(esrrg),ENSDARG00000011696(esrrgb),ENSDARG00000040151,ENSDARG00000015064(esrrd)" "ENSXETG00000013217(),ENSXETG00000020932(ESRRG),ENSXETG00000007211(ESRRA),ENSXETG00000016948()" "ENSMUSG00000021255(Esrrb),ENSMUSG00000026610(Esrrg),ENSMUSG00000024955(Esrra)" "ENSG00000119715(ESRRB),ENSG00000196482(ESRRG),ENSG00000173153(ESRRA)" "lethal - all die before end of second instar larval stage,some die during second instar larval stage" FBgn0020557 bb-ë¬ bb-ë¬ http://flybase.net/reports/FBgn0020557.html pseudogene_attribute "PsirDNA, 18S rRNA pseudogene" 16-Dec-15 2015_12 FBgn0266039 CR44804 http://flybase.net/reports/FBgn0266039.html non_protein_coding_gene lincRNA.223 CR44804 16-Dec-15 2015_12 FBgn0264401 FCG-D http://flybase.net/reports/FBgn0264401.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0005504 l(2)24EFb lethal (2) 24EFb http://flybase.net/reports/FBgn0005504.html gene l(2)Gr.II 16-Dec-15 2015_12 "lethal,recessive" FBgn0060594 l(3)S092302 lethal (3) S092302 http://flybase.net/reports/FBgn0060594.html gene 0923/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0033342 CG8258 http://flybase.net/reports/FBgn0033342.html protein_coding_gene "0042623=ATPase activity, coupled, 0051082=unfolded protein binding, 0005524=ATP binding" "0031122=cytoplasmic microtubule organization, 0007052=mitotic spindle organization, 0006457=protein folding" "0005832=chaperonin-containing T-complex, 0005886=plasma membrane, 0005875=microtubule associated complex" "Tcp1-theta, CCT8, TCP-1theta, Q7K3J0_DROME" "IPR002194=Chaperonin TCP-1, conserved site, IPR012721=T-complex protein 1, theta subunit, IPR027410=TCP-1-like chaperonin intermediate domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1), IPR027413=GroEL-like equatorial domain, IPR027409=GroEL-like apical domain" CG8258 16-Dec-15 2015_12 ENSDARG00000008243(cct8) YJL008C(CCT8) WBGene00021934(cct-8) ENSXETG00000020262(cct8) ENSMUSG00000025613(Cct8) ENSG00000156261(CCT8) FBgn0015293 Sebp3 Secretion enhancer-binding protein 3 http://flybase.net/reports/FBgn0015293.html gene 0000976=transcription regulatory region sequence-specific DNA binding 0045944=positive regulation of transcription from RNA polymerase II promoter 0005634=nucleus SEBP3 16-Dec-15 2015_12 larval stage | third instar embryonic/larval salivary gland

FBgn0001707 l(1)ESHS28 lethal (1) ESHS28 http://flybase.net/reports/FBgn0001707.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033539 Git G protein-coupled receptor kinase interacting ArfGAP http://flybase.net/reports/FBgn0033539.html protein_coding_gene "0032947=protein complex scaffold, 0005096=GTPase activator activity" "0043087=regulation of GTPase activity, 0046620=regulation of organ growth, 0035332=positive regulation of hippo signaling, 0007525=somatic muscle development" "0005737=cytoplasm, 0031252=cell leading edge" "CG16728, git, G-protein-coupled receptor kinase-interacting protein, CT37209, arfgap2, dGit, dgit" "IPR022018=ARF GTPase-activating protein GIT1, C-terminal, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR001164=Arf GTPase activating protein, IPR013724=GIT, Spa2 homology (SHD) domain" CG16728 16-Dec-15 2015_12 "ENSDARG00000061915(git2a),ENSDARG00000042791(git2b),ENSDARG00000039489(LOC568935)" WBGene00008805(git-1) "ENSXETG00000018638(GIT2),ENSXETG00000009445(GIT1)" "ENSMUSG00000011877(Git1),ENSMUSG00000041890(Git2)" "ENSG00000139436(GIT2),ENSG00000108262(GIT1)" "partially lethal - majority die,recessive" "wing,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,A1-7 ventral acute muscle 3,lateral transverse muscle,A1-7 lateral oblique muscle 1" FBgn0001069 Fs(3)Var Female sterile (3) Varas http://flybase.net/reports/FBgn0001069.html gene "Fs(3)Varas, Var, Fs(3)Sz24" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0026610 AT21 AT21 http://flybase.net/reports/FBgn0026610.html gene 16-Dec-15 2015_12 FBgn0038208 CG14355 http://flybase.net/reports/FBgn0038208.html protein_coding_gene CG14355 16-Dec-15 2015_12 viable FBgn0069112 mus218 mutagen-sensitive 218 http://flybase.net/reports/FBgn0069112.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0032364 CG4970 http://flybase.net/reports/FBgn0032364.html "FBgn0044692, FBgn0052953" protein_coding_gene "CG32953, anon-WO0140519.184" IPR025254=Domain of unknown function DUF4201 CG4970 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0265258 gbb::Hsap\BMP7 http://flybase.net/reports/FBgn0265258.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0070026 BG00378 BG00378 http://flybase.net/reports/FBgn0070026.html gene 16-Dec-15 2015_12 stress response defective FBgn0037070 CG11309 http://flybase.net/reports/FBgn0037070.html protein_coding_gene "IPR018247=EF-Hand 1, calcium-binding site, IPR000073=Alpha/beta hydrolase fold-1, IPR029058=Alpha/Beta hydrolase fold" CG11309 16-Dec-15 2015_12 ENSDARG00000032340(serhl) "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" ENSMUSG00000058586(Serhl) "ENSG00000183569(SERHL2),ENSG00000172250" "viable,fertile" FBgn0261585 CG42695 http://flybase.net/reports/FBgn0261585.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005148 l(2)DTS19 lethal (2) DTS19 http://flybase.net/reports/FBgn0005148.html gene DTS-L19 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0003675 Tcp Third cold paralytic http://flybase.net/reports/FBgn0003675.html gene "Third chromosome cold-sensitive paralytic, TCP" 16-Dec-15 2015_12 partially lethal - majority die FBgn0036663 CG9674 http://flybase.net/reports/FBgn0036663.html protein_coding_gene "0010181=FMN binding, 0016040=glutamate synthase (NADH) activity, 0051536=iron-sulfur cluster binding, 0005506=iron ion binding, 0050660=flavin adenine dinucleotide binding, 0004355=glutamate synthase (NADPH) activity" "0006537=glutamate biosynthetic process, 0055114=oxidation-reduction process" Glutamate synthase "IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR013785=Aldolase-type TIM barrel, IPR028261=Dihydroprymidine dehydrogenase domain II, IPR006982=Glutamate synthase, central-N, IPR006005=Glutamate synthase, NADH/NADPH, small subunit 1, IPR012220=Glutamate synthase, eukaryotic, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR002932=Glutamate synthase domain, IPR002489=Glutamate synthase, alpha subunit, C-terminal, IPR016040=NAD(P)-binding domain, IPR017932=Glutamine amidotransferase type 2 domain, IPR009051=Alpha-helical ferredoxin" CG9674 16-Dec-15 2015_12 YDL171C(GLT1) WBGene00012326(W07E11.1) "viable,fertile" FBgn0020802 ms(3)D120 ms(3)D120 http://flybase.net/reports/FBgn0020802.html gene 3-D120 16-Dec-15 2015_12 "chemical sensitive,recessive,male sterile" FBgn0020535 l(2)k06003 lethal (2) k06003 http://flybase.net/reports/FBgn0020535.html gene l(2)06003 16-Dec-15 2015_12 "lethal,recessive" FBgn0024187 syd sunday driver http://flybase.net/reports/FBgn0024187.html FBgn0035826 protein_coding_gene "0005078=MAP-kinase scaffold activity, 0019894=kinesin binding" "0046328=regulation of JNK cascade, 0008088=axon cargo transport" "0016020=membrane, 0030140=trans-Golgi network transport vesicle, 0016021=integral component of membrane, 0000139=Golgi membrane" "CG8110, JIP-3, jip3, Syd" "IPR011044=Quinoprotein amine dehydrogenase, beta chain-like, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019143=JNK/Rab-associated protein-1, N-terminal" CG8110 16-Dec-15 2015_12 ENSDARG00000062531 WBGene00006755(unc-16) ENSXETG00000011059(SPAG9) "ENSMUSG00000020859(Spag9),ENSMUSG00000024163(Mapk8ip3)" "ENSG00000008294(SPAG9),ENSG00000138834(MAPK8IP3)" "viable,fertile,neuroanatomy defective,hypoactive,recessive,behavior defective,lethal - all die before end of larval stage,some die during larval stage" "NMJ bouton,larva,abdominal segmental nerve,synaptic vesicle" FBgn0015976 l(2)PC4-B lethal (2) PC4-B http://flybase.net/reports/FBgn0015976.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015404 l(1)11BEa lethal (1) 11BEa http://flybase.net/reports/FBgn0015404.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026350 Su(dalyh)22C1 Su(dalyh)22C1 http://flybase.net/reports/FBgn0026350.html gene Su(da[lyh]) 16-Dec-15 2015_12 FBgn0053467 CG33467 http://flybase.net/reports/FBgn0053467.html protein_coding_gene unnamed "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG33467 16-Dec-15 2015_12 FBgn0035482 CG14985 http://flybase.net/reports/FBgn0035482.html protein_coding_gene IPR007330=MIT CG14985 16-Dec-15 2015_12 ENSDARG00000044766(mitd1) WBGene00013436(Y66D12A.10) ENSXETG00000019386(TEgg072n07.1) ENSMUSG00000026088(Mitd1) ENSG00000158411(MITD1) viable FBgn0083074 ms(3)o33 ms(3)o33 http://flybase.net/reports/FBgn0083074.html gene 16-Dec-15 2015_12 FBgn0002190 l(3)63Ba lethal (3) 63Ba http://flybase.net/reports/FBgn0002190.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0050457 CG30457 http://flybase.net/reports/FBgn0050457.html FBgn0034203 protein_coding_gene "CG30457-PA, CG17288" CG30457 16-Dec-15 2015_12 "viable,fertile" DRSC06661 E 0.555847597 -0.123067244 -1.306870128 1.664267094 -0.570767548 0.434728687 FBgn0069140 mcl(3)Z5502 mcl(3)Z5502 http://flybase.net/reports/FBgn0069140.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0065931 l(2)SH0134 lethal (2) SH0134 http://flybase.net/reports/FBgn0065931.html gene l(2)SH2 0134 16-Dec-15 2015_12 "lethal,recessive" FBgn0259268 C375 http://flybase.net/reports/FBgn0259268.html gene 16-Dec-15 2015_12 visible "wing hair,wing vein,chaeta" FBgn0039827 CG1544 http://flybase.net/reports/FBgn0039827.html protein_coding_gene "0030976=thiamine pyrophosphate binding, 0004591=oxoglutarate dehydrogenase (succinyl-transferring) activity" "0006099=tricarboxylic acid cycle, 0006091=generation of precursor metabolites and energy" 0031966=mitochondrial membrane "IPR005475=Transketolase-like, pyrimidine-binding domain, IPR011603=2-oxoglutarate dehydrogenase E1 component, IPR029061=Thiamin diphosphate-binding fold, IPR001017=Dehydrogenase, E1 component" CG1544 16-Dec-15 2015_12 ENSDARG00000016415(LOC100334699) WBGene00014098(ZK836.2) ENSXETG00000021954(DHTKD1) ENSMUSG00000025815(Dhtkd1) ENSG00000181192(DHTKD1) "viable,fertile" DRSC15036 K 0.161373115 -0.28246628 0.667221183 0.795827835 -1.710257735 -0.121167206 FBgn0035357 MEP-1 MEP-1 http://flybase.net/reports/FBgn0035357.html "FBgn0025995, FBgn0061858" protein_coding_gene "0005515=protein binding, 0046872=metal ion binding, 0003682=chromatin binding, 0070615=nucleosome-dependent ATPase activity" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis" "0005700=polytene chromosome, 0005654=nucleoplasm, 0016581=NuRD complex, 0005634=nucleus" "dMEP-1, CG1244, MEP-1, anon-EST:Liang-1.37, anon-WO0118547.584, MEP1, Q0E8J0_DROME, clone 1.37" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG1244 16-Dec-15 2015_12 WBGene00003218(mep-1) "ENSMUSG00000005621(Zfp592),ENSMUSG00000019338(Zfp687),ENSMUSG00000042439(Zfp532)" "lethal,recessive" DRSC29362 IK 4.475491095 -2.329759529 1.000530012 -0.046388653 1.722342271 1.761416358 FBgn0085288 CG34259 http://flybase.net/reports/FBgn0085288.html protein_coding_gene CG34259 16-Dec-15 2015_12 FBgn0036294 CG10654 http://flybase.net/reports/FBgn0036294.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like" CG10654 16-Dec-15 2015_12 viable FBgn0259284 EP-322 http://flybase.net/reports/FBgn0259284.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0001914 l(2)25Ba lethal (2) 25Ba http://flybase.net/reports/FBgn0001914.html gene "l(2)jf10, jf10" 16-Dec-15 2015_12 lethal FBgn0035097 CG13405 http://flybase.net/reports/FBgn0035097.html FBgn0063347 protein_coding_gene BcDNA:AT11049 CG13405 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267847 T:CRAT-PTS1 PTS1 peroxisomal matrix targeting signal of CRAT http://flybase.net/reports/FBgn0267847.html engineered_tag 16-Dec-15 2015_12 FBgn0027960 l(3)S147006 lethal (3) S147006 http://flybase.net/reports/FBgn0027960.html gene 1470/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0030221 Rab9Db Rab at 9Db http://flybase.net/reports/FBgn0030221.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0015031=protein transport, 0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction" 0031982=vesicle "CG9807, Rab GTPase 9Db" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain" CG9807 16-Dec-15 2015_12 FBgn0041764 aos::fng argos::fng http://flybase.net/reports/FBgn0041764.html engineered_fusion_gene argos::fng 16-Dec-15 2015_12 eye FBgn0034807 CG9897 http://flybase.net/reports/FBgn0034807.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH195 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG9897 16-Dec-15 2015_12 "viable,mating behavior defective,female limited" FBgn0001838 l(1)ts982 lethal (1) ts982 http://flybase.net/reports/FBgn0001838.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0004761 l(3)89Cb lethal (3) 89Cb http://flybase.net/reports/FBgn0004761.html gene 16-Dec-15 2015_12 lethal FBgn0000637 fbr fine bristles http://flybase.net/reports/FBgn0000637.html gene fb 16-Dec-15 2015_12 visible macrochaeta FBgn0000785 fs(1)A1578 female sterile (1) A1578 http://flybase.net/reports/FBgn0000785.html gene fs(1)1578 16-Dec-15 2015_12 "female sterile,recessive,lethal,non-rescuable maternal effect" egg FBgn0036426 CG9592 http://flybase.net/reports/FBgn0036426.html protein_coding_gene CG9592 16-Dec-15 2015_12 "viable,fertile" DRSC11078 I 2.214554638 -0.524720924 0.550581523 1.165977991 -0.079879246 -0.456965957 FBgn0016756 Usp47 Ubiquitin specific protease 47 http://flybase.net/reports/FBgn0016756.html "FBgn0013225, FBgn0047212" protein_coding_gene 0004843=ubiquitin-specific protease activity "0031935=regulation of chromatin silencing, 0042675=compound eye cone cell differentiation, 0006508=proteolysis, 0050821=protein stabilization, 0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" "0005737=cytoplasm, 0005634=nucleus" "Ubp64E, UBP, CG5486, D-Ubp-64E, BcDNA:LD12764, dUbp64, E(var)1, dUSP47, ubp64E, Ubp64, Ubiquitin-specific protease 64E, E-var(3)64E, ubp64, Q24574, D-UBP-64E, E(var)3-64E" "IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain" CG5486 16-Dec-15 2015_12 ENSDARG00000052715 WBGene00011507(T05H10.1) ENSXETG00000013696(USP47) ENSMUSG00000059263(Usp47) ENSG00000170242(USP47) " embryonic stage , embryonic stage -- adult stage "

ubiquitous "visible,viable,enhancer of variegation,dominant,fertile,lethal,short lived,locomotor behavior defective" "eye,ommatidium | adult stage,interommatidial bristle,eye disc | pupal stage,cone cell | pupal stage,photoreceptor cell | pupal stage,ommatidium,supernumerary,eye disc,cone cell,photoreceptor cell,testis,medial triple row,germline cell,male,wing" DRSC11313 K 1.281316321 0.412417825 0.074395258 0.357223098 -1.883589115 -1.576330818 FBgn0261060 Sfp93F Seminal fluid protein 93F http://flybase.net/reports/FBgn0261060.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG42608 16-Dec-15 2015_12 FBgn0062616 Mod(var)1250 Mod(var)1250 http://flybase.net/reports/FBgn0062616.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1250 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,viable" FBgn0266510 s-460 http://flybase.net/reports/FBgn0266510.html gene 16-Dec-15 2015_12 FBgn0026257 cav caravaggio http://flybase.net/reports/FBgn0026257.html FBgn0020360 protein_coding_gene "0042162=telomeric DNA binding, 0003735=structural constituent of ribosome, 0005515=protein binding, 0003696=satellite DNA binding" "0016233=telomere capping, 0000723=telomere maintenance, 0022008=neurogenesis" "0000782=telomere cap complex, 0000775=chromosome, centromeric region, 0000784=nuclear chromosome, telomeric region, 0005634=nucleus, 0000781=chromosome, telomeric region, 0005763=mitochondrial small ribosomal subunit" "1G5, HP1/ORC-associated protein, hoap, p55, Hoap, anon-EST:fe1G5, anon-fast-evolving-1G5, anonymous fast evolving gene IG5, Caravaggio, Anon1G5, CG6219, HOAP, HP1/ORC-Associated Protein, HP1 and Orc-associated protein, anon fe 1G5, anon1G5, Drosophila anonymous fast evolving 1G5" IPR026299=Mitochondrial 28S ribosomal protein S31 CG6219 16-Dec-15 2015_12 "lethal,male limited,maternal effect,partially lethal - majority die,dominant,recessive,neuroanatomy defective,suppressor of variegation,partially,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,body color defective,fertile" "neuroblast,mitotic metaphase,metaphase & condensed nuclear chromosome,chromosome, telomeric region,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0082357 HM210 HM210 http://flybase.net/reports/FBgn0082357.html gene 16-Dec-15 2015_12 FBgn0263553 mir-4913 mir-4913 stem loop http://flybase.net/reports/FBgn0263553.html miRNA_gene "CR43538, dme-mir-4913" CR43538 16-Dec-15 2015_12 FBgn0037619 CG8159 http://flybase.net/reports/FBgn0037619.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG8159 16-Dec-15 2015_12 WBGene00010770(K11D2.4) viable FBgn0026434 En(tkv*)3-3 En(tkv*)3-3 http://flybase.net/reports/FBgn0026434.html gene En(Tkv*)3-3 16-Dec-15 2015_12 FBgn0038763 CG4433 http://flybase.net/reports/FBgn0038763.html protein_coding_gene "IPR003737=N-acetylglucosaminyl phosphatidylinositol deacetylase-related, IPR024078=Putative deacetylase LmbE-like domain" CG4433 16-Dec-15 2015_12 ENSDARG00000067752(pigl) YMR281W(GPI12) ENSXETG00000006719(PIGL) ENSMUSG00000014245(Pigl) ENSG00000108474(PIGL) viable DRSC15577 K 0.232038324 0.205327486 -0.119173187 0.460269568 2.29121056 0.4943438 FBgn0037415 Osi8 Osiris 8 http://flybase.net/reports/FBgn0037415.html protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG15591" IPR012464=Protein of unknown function DUF1676 CG15591 16-Dec-15 2015_12 viable FBgn0065144 l(3)SH093 lethal (3) SH093 http://flybase.net/reports/FBgn0065144.html gene l(2)SH3 093 16-Dec-15 2015_12 "lethal,recessive" FBgn0031501 CG17261 http://flybase.net/reports/FBgn0031501.html protein_coding_gene CG17261 16-Dec-15 2015_12 FBgn0040814 CG14113 http://flybase.net/reports/FBgn0040814.html protein_coding_gene CG14113 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0040327 EY3-4 EY3-4 http://flybase.net/reports/FBgn0040327.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043068 MstProx::Tl MstProx::Tl http://flybase.net/reports/FBgn0043068.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0267943 CR46223 http://flybase.net/reports/FBgn0267943.html non_protein_coding_gene lincRNA.705 CR46223 16-Dec-15 2015_12 FBgn0040467 Dlip1 Dorsal interacting protein 1 http://flybase.net/reports/FBgn0040467.html FBgn0030095 protein_coding_gene "0003690=double-stranded DNA binding, 0008270=zinc ion binding" 0046331=lateral inhibition 0005634=nucleus "DIP1, Dip1, CG15367, dip1" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type" CG15367 16-Dec-15 2015_12 "viable,visible" "chaeta,mesothoracic tergum" FBgn0265670 CG44477 http://flybase.net/reports/FBgn0265670.html protein_coding_gene CG44477 16-Dec-15 2015_12 FBgn0265580 CR44407 http://flybase.net/reports/FBgn0265580.html non_protein_coding_gene CR44407 16-Dec-15 2015_12 FBgn0029899 CG14438 http://flybase.net/reports/FBgn0029899.html protein_coding_gene 0046872=metal ion binding "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG14438 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective,female sterile" neurite | pharate adult stage FBgn0015414 l(1)15ACa lethal (1) 15ACa http://flybase.net/reports/FBgn0015414.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263466 snoRNA:lola-a http://flybase.net/reports/FBgn0263466.html snoRNA_gene CR43581 16-Dec-15 2015_12 FBgn0040343 CG3713 http://flybase.net/reports/FBgn0040343.html "FBgn0040891, FBgn0063251" protein_coding_gene "BcDNA:GH13231, EG:BACR7A4.2" CG3713 16-Dec-15 2015_12 viable FBgn0260294 GSd079 http://flybase.net/reports/FBgn0260294.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0037310 Tim17b1 Tim17b1 http://flybase.net/reports/FBgn0037310.html FBgn0063326 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0006626=protein targeting to mitochondrion, 0015031=protein transport" 0005744=mitochondrial inner membrane presequence translocase complex "BcDNA:AT16284, CG1158" "IPR003397=Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24, IPR005678=Mitochondrial inner membrane translocase complex, subunit Tim17" CG1158 16-Dec-15 2015_12 YJL143W(TIM17) WBGene00017119(E04A4.5) viable FBgn0040113 l(2)AR-49 lethal (2) AR-49 http://flybase.net/reports/FBgn0040113.html gene 16-Dec-15 2015_12 lethal FBgn0262541 CG43095 http://flybase.net/reports/FBgn0262541.html protein_coding_gene CG43095 16-Dec-15 2015_12 FBgn0004181 Ebp Ejaculatory bulb protein http://flybase.net/reports/FBgn0004181.html "FBgn0028493, FBgn0044740" protein_coding_gene "0042628=mating plug formation, 0045297=post-mating behavior, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "peb, PEB-me, BcDNA:GH06048, P38, anon-WO0140519.140, ejaculatory bulb protein, CG2668, Peb, Protein ejaculatory bulb, PEB" CG2668 16-Dec-15 2015_12 viable FBgn0033301 CG12780 http://flybase.net/reports/FBgn0033301.html protein_coding_gene 0030246=carbohydrate binding "0051607=defense response to virus, 0009595=detection of biotic stimulus" 0009986=cell surface GNBP-like CG12780 16-Dec-15 2015_12 viable FBgn0066375 arap arap http://flybase.net/reports/FBgn0066375.html gene "0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 "learning defective,memory defective" FBgn0262540 CG43094 http://flybase.net/reports/FBgn0262540.html protein_coding_gene CG43094 16-Dec-15 2015_12 FBgn0261939 robo1::robo3 http://flybase.net/reports/FBgn0261939.html engineered_fusion_gene robo::robo3 16-Dec-15 2015_12 FBgn0266431 CG45061 http://flybase.net/reports/FBgn0266431.html protein_coding_gene "CG42262, CG32696, CG15246, CG15245" CG45061 16-Dec-15 2015_12 FBgn0085704 CG41578 http://flybase.net/reports/FBgn0085704.html FBan0041578 protein_coding_gene 16-Dec-15 2015_12 FBgn0010026 E(Dl)F14 Enhancer of Delta F14 http://flybase.net/reports/FBgn0010026.html gene 16-Dec-15 2015_12 FBgn0259363 EP-947 http://flybase.net/reports/FBgn0259363.html gene 16-Dec-15 2015_12 visible wing FBgn0265892 CR44681 http://flybase.net/reports/FBgn0265892.html non_protein_coding_gene CR44681 16-Dec-15 2015_12 FBgn0266872 CR45333 http://flybase.net/reports/FBgn0266872.html non_protein_coding_gene CR45333 16-Dec-15 2015_12 FBgn0023084 fldA flight defective A http://flybase.net/reports/FBgn0023084.html gene 0007517=muscle organ development unnamed 16-Dec-15 2015_12 "flightless,recessive" "indirect flight muscle,myofibril,mitochondrial membrane,nervous system,giant fiber neuron" FBgn0005137 l(2)39a lethal (2) 39a http://flybase.net/reports/FBgn0005137.html gene 16-Dec-15 2015_12 lethal FBgn0042159 CG18836 http://flybase.net/reports/FBgn0042159.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002113 l(2)ay lethal (2) ay http://flybase.net/reports/FBgn0002113.html gene 16-Dec-15 2015_12 lethal FBgn0267184 CR45624 http://flybase.net/reports/FBgn0267184.html non_protein_coding_gene CR45624 16-Dec-15 2015_12 FBgn0028836 CSN7 COP9 signalosome subunit 7 http://flybase.net/reports/FBgn0028836.html FBgn0033291 protein_coding_gene 0005515=protein binding "0048142=germarium-derived cystoblast division, 0007281=germ cell development, 0010388=cullin deneddylation, 0048140=male germ-line cyst encapsulation, 0051726=regulation of cell cycle, 0050821=protein stabilization, 0007095=mitotic G2 DNA damage checkpoint, 0036099=female germ-line stem cell maintenance, 0046331=lateral inhibition" "0008180=COP9 signalosome, 0034399=nuclear periphery" "COP9 complex homolog subunit 7, csn7, CG2038, Drosophila COP9 signalosome homolog 7, Dch7, CSN7b, CH7, Csn7" IPR000717=Proteasome component (PCI) domain CG2038 16-Dec-15 2015_12 ENSDARG00000022788 ENSXETG00000022761(COPS7B) "ENSMUSG00000026240(Cops7b),ENSMUSG00000030127(Cops7a)" "ENSG00000111652(COPS7A),ENSG00000144524(COPS7B)" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell" DRSC06807 K 0.0486661 -0.174383387 -0.62619243 0.156327332 1.168020166 2.699860172 FBgn0016037 mis-b mis-b http://flybase.net/reports/FBgn0016037.html gene 0007423=sensory organ development mis b 16-Dec-15 2015_12 FBgn0060628 l(3)S087106 lethal (3) S087106 http://flybase.net/reports/FBgn0060628.html gene 0871/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0034573 CG3295 http://flybase.net/reports/FBgn0034573.html protein_coding_gene "IPR027711=Rmd5, IPR024964=CTLH/CRA C-terminal to LisH motif domain, IPR027370=RING-type zinc-finger, LisH dimerisation motif, IPR013144=CRA domain, IPR006595=CTLH, C-terminal LisH motif, IPR006594=LIS1 homology motif" CG3295 16-Dec-15 2015_12 ENSDARG00000043359(rmnd5b) YDR255C(RMD5) WBGene00020301(T07D1.2) ENSXETG00000001924(TGas140j12.1) "ENSMUSG00000002222(Rmnd5a),ENSMUSG00000001054(Rmnd5b)" "ENSG00000153561(RMND5A),ENSG00000145916(RMND5B)" "viable,body color defective" mesothoracic tergum DRSC04356 EK 1.077589839 -1.086036782 -1.535579799 -0.357837638 2.759762461 0.018978343 FBgn0038819 Cpr92F Cuticular protein 92F http://flybase.net/reports/FBgn0038819.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG5494 IPR000618=Insect cuticle protein CG5494 16-Dec-15 2015_12 "viable,fertile" FBgn0016976 stnA stoned A http://flybase.net/reports/FBgn0016976.html "FBan0012500, FBgn0003533, FBgn0058306, FBgn0063778" protein_coding_gene 0005515=protein binding "0016079=synaptic vesicle exocytosis, 0048489=synaptic vesicle transport, 0048488=synaptic vesicle endocytosis, 0009612=response to mechanical stimulus, 0007629=flight behavior, 0007269=neurotransmitter secretion" "0030139=endocytic vesicle, 0008021=synaptic vesicle, 0005886=plasma membrane" "l(1)20Bc, 32, X-43, l8P1, x-3, stress-sensitive-C, STNA, CG12500, section 31, section 32, l(1)13-20, ORF1, 20, stn, 8P1, CG12473/CG12500, unnamed, 31, stoned, section 20, sesC, X-3, l(1)X-3, stonedA, X3, lR9-10, stn-A, CG40306" CG12500 16-Dec-15 2015_12 adult stage adult stage " adult thorax

, adult head

, adult abdomen

" "lethal - all die before end of embryonic stage,some die during embryonic stage,uncoordinated,recessive,neurophysiology defective,lethal,behavior defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,neuroanatomy defective,locomotor behavior defective,viable,bang sensitive,jumping defective,paralytic,partially lethal - majority die" "axon terminus,synaptic vesicle,multivesicular body,indirect flight muscle" FBgn0061149 l(3)85Da-2 lethal (3) 85Da-2 http://flybase.net/reports/FBgn0061149.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002168 l(2)Sp10 lethal (2) Sp10 http://flybase.net/reports/FBgn0002168.html gene 16-Dec-15 2015_12 lethal FBgn0040558 CG14361 http://flybase.net/reports/FBgn0040558.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085811 CR41598 http://flybase.net/reports/FBgn0085811.html FBan0041598 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0038866 CG5810 http://flybase.net/reports/FBgn0038866.html protein_coding_gene CT18214 "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG5810 16-Dec-15 2015_12 viable FBgn0262849 CR43213 http://flybase.net/reports/FBgn0262849.html pseudogene_attribute "noncoding_23159, noncoding_23161" CR43213 16-Dec-15 2015_12 FBgn0085537 CG40928 http://flybase.net/reports/FBgn0085537.html FBan0040928 protein_coding_gene 16-Dec-15 2015_12 FBgn0030894 CG7192 http://flybase.net/reports/FBgn0030894.html protein_coding_gene 0043130=ubiquitin binding 0032509=endosome transport via multivesicular body sorting pathway 0000813=ESCRT I complex "IPR023341=MABP domain, IPR018798=FAM125, IPR023340=UMA domain" CG7192 16-Dec-15 2015_12 "ENSMUSG00000031813(Fam125a),ENSMUSG00000038740(Fam125b)" "viable,fertile" FBgn0263859 P95 P95 http://flybase.net/reports/FBgn0263859.html gene 0007613=memory 16-Dec-15 2015_12 "memory defective,recessive" FBgn0051813 CG31813 http://flybase.net/reports/FBgn0051813.html "FBgn0028846, FBgn0064869" protein_coding_gene "BG:DS08249.4, BcDNA:RE62259" CG31813 16-Dec-15 2015_12 viable FBgn0001734 l(1)HM2 lethal (1) HM2 http://flybase.net/reports/FBgn0001734.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive" FBgn0065137 l(3)SH115 lethal (3) SH115 http://flybase.net/reports/FBgn0065137.html gene l(2)SH3 115 16-Dec-15 2015_12 "lethal,recessive" FBgn0039611 CG14528 http://flybase.net/reports/FBgn0039611.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR018497=Peptidase M13, C-terminal domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR024079=Metallopeptidase, catalytic domain" CG14528 16-Dec-15 2015_12 FBgn0061154 l(2)B73 lethal (2) B73 http://flybase.net/reports/FBgn0061154.html gene B73 16-Dec-15 2015_12 "lethal,recessive" FBgn0051755 SoYb Sister of Yb http://flybase.net/reports/FBgn0051755.html FBgn0032173 protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0010526=negative regulation of transposition, RNA-mediated" 0070725=Yb body "sister of Yb, CG5831, CG31755" "IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR002999=Tudor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG31755 16-Dec-15 2015_12 FBgn0047334 BG642312 BG642312 http://flybase.net/reports/FBgn0047334.html FBgn0053943 protein_coding_gene "0048042=regulation of post-mating oviposition, 0032504=multicellular organism reproduction" 0005615=extracellular space "BG642312(4h1), pncr010:3L, CG33943, CR33943, BcDNA:AT24650, 4h1, putative noncoding RNA 010:3L" CG33943 16-Dec-15 2015_12 viable FBgn0025560 anon-66Fa anon-66Fa http://flybase.net/reports/FBgn0025560.html gene 16-Dec-15 2015_12 FBgn0083972 CG34136 http://flybase.net/reports/FBgn0083972.html protein_coding_gene CG34136 16-Dec-15 2015_12 FBgn0000842 fs(1)M29 female sterile (1) M29 http://flybase.net/reports/FBgn0000842.html gene "fs(1)posterior midgut defect, fs(1)151" 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0033723 CG13155 http://flybase.net/reports/FBgn0033723.html protein_coding_gene CG13155 16-Dec-15 2015_12 "viable,fertile" FBgn0030230 Rph Rabphilin http://flybase.net/reports/FBgn0030230.html protein_coding_gene "0008565=protein transporter activity, 0005544=calcium-dependent phospholipid binding, 0017137=Rab GTPase binding" "0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0016079=synaptic vesicle exocytosis, 0007269=neurotransmitter secretion, 0048488=synaptic vesicle endocytosis, 0017157=regulation of exocytosis" "0016021=integral component of membrane, 0008021=synaptic vesicle, 0030141=secretory granule, 0030672=synaptic vesicle membrane" "Rabphilin-3A, CG11556, rabphilin-3A, dm-rabphilin" "IPR017455=Zinc finger, FYVE-related, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR010911=Rab-binding domain, IPR030538=Rab effector Noc2, IPR000008=C2 domain, IPR001565=Synaptotagmin, IPR011011=Zinc finger, FYVE/PHD-type" CG11556 16-Dec-15 2015_12 ENSDARG00000063436 WBGene00004316(rbf-1) ENSXETG00000011467(RPH3A) "ENSMUSG00000029608(Rph3a),ENSMUSG00000020848(Doc2b),ENSMUSG00000052301(Doc2a)" "ENSG00000089169(RPH3A),ENSG00000215770" FBgn0002337 l(3)87Bf lethal (3) 87Bf http://flybase.net/reports/FBgn0002337.html gene "l(3)ck18, 1418/03, ck18" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive" FBgn0035642 CG18586 http://flybase.net/reports/FBgn0035642.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase" CG18586 16-Dec-15 2015_12 viable FBgn0263613 CR43622 http://flybase.net/reports/FBgn0263613.html non_protein_coding_gene CR43622 16-Dec-15 2015_12 FBgn0085656 CG41495 http://flybase.net/reports/FBgn0085656.html FBan0041495 protein_coding_gene 16-Dec-15 2015_12 FBgn0041104 neuro-d4 neuro-d4 http://flybase.net/reports/FBgn0041104.html gene unnamed 16-Dec-15 2015_12 FBgn0031620 CG11929 http://flybase.net/reports/FBgn0031620.html protein_coding_gene CG11929 16-Dec-15 2015_12 viable FBgn0000447 Dhod Dihydroorotate dehydrogenase http://flybase.net/reports/FBgn0000447.html FBgn0024585 protein_coding_gene 0004152=dihydroorotate dehydrogenase activity "0055114=oxidation-reduction process, 0006207='de novo' pyrimidine nucleobase biosynthetic process" "0005758=mitochondrial intermembrane space, 0005743=mitochondrial inner membrane" "DHODH, DHOD, dihydroorotate dehydrogenase, dhod, l(3)s3512, CG9741" "IPR013785=Aldolase-type TIM barrel, IPR001295=Dihydroorotate dehydrogenase, conserved site, IPR005720=Dihydroorotate dehydrogenase domain, IPR005719=Dihydroorotate dehydrogenase, class 2" CG9741 16-Dec-15 2015_12 ENSDARG00000051889(dhodh) YKL216W(URA1) WBGene00020932(dhod-1) ENSXETG00000023444(dhodh) ENSMUSG00000031730(Dhodh) ENSG00000102967(DHODH) embryonic stage -- adult stage spermatogenesis && adult stage spermatid

"lethal,recessive,visible,viable,female fertile,wild-type,female sterile" "eye,arista,wing,wing hair" DRSC16647 K 0.139349397 0.006712879 0.262450955 -0.189907611 1.571456147 0.056783255 FBgn0034956 CG4324 http://flybase.net/reports/FBgn0034956.html protein_coding_gene 0015101=organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG4324 16-Dec-15 2015_12 "ENSDARG00000056833(LOC559162),ENSDARG00000014951(LOC555216)" "YNL065W(AQR1),YIL121W(QDR2),YIL120W(QDR1),YBR043C(QDR3),YBR180W(DTR1)" WBGene00014021(ZK637.1) ENSXETG00000022304(SVOP) ENSMUSG00000042078(Svop) ENSG00000166111(SVOP) viable FBgn0033195 CG1360 http://flybase.net/reports/FBgn0033195.html protein_coding_gene CG1360 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0039601 CG1523 http://flybase.net/reports/FBgn0039601.html protein_coding_gene "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG1523 16-Dec-15 2015_12 ENSDARG00000029600(wdr32) ENSXETG00000002243(wdr32) ENSMUSG00000035572(Dcaf10) "viable,visible" "embryonic/larval salivary gland,chaeta,supernumerary" DRSC15033 K 0.665839094 0.839717609 0.059182283 0.363573151 0.456537576 1.560785225 FBgn0263626 CR43635 http://flybase.net/reports/FBgn0263626.html non_protein_coding_gene lincRNA.676 CR43635 16-Dec-15 2015_12 FBgn0036292 CG10646 http://flybase.net/reports/FBgn0036292.html FBgn0046378 protein_coding_gene anon-WO0172774.52 "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG10646 16-Dec-15 2015_12 ENSDARG00000043417(zgc:101720) WBGene00013599(Y87G2A.11) ENSXETG00000006962(tssc1) ENSMUSG00000036613(Tssc1) ENSG00000032389(TSSC1) viable FBgn0243500 l(3)CB02667 http://flybase.net/reports/FBgn0243500.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0021782 l(3)95BCc lethal (3) 95BCc http://flybase.net/reports/FBgn0021782.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032190 CG5739 http://flybase.net/reports/FBgn0032190.html protein_coding_gene IPR029428=FAM195 16-Dec-15 2015_12 FBgn0264657 panting panting http://flybase.net/reports/FBgn0264657.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0261787 bru brunelleschi http://flybase.net/reports/FBgn0261787.html "FBgn0061518, FBgn0032872" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0043147=meiotic spindle stabilization, 0000916=actomyosin contractile ring contraction, 0007111=meiosis II cytokinesis, 0000281=mitotic cytokinesis, 0007112=male meiosis cytokinesis, 0006891=intra-Golgi vesicle-mediated transport, 0007110=meiosis I cytokinesis, 0048137=spermatocyte division, 0043087=regulation of GTPase activity" "0036063=acroblast, 0005794=Golgi apparatus, 0030008=TRAPP complex, 0005737=cytoplasm" "CG2478, 38D.28" "IPR013935=TRAPP II complex, Trs120" CG2478 16-Dec-15 2015_12 ENSDARG00000059149 YDR407C(TRS120) WBGene00007956(C35C5.6) ENSXETG00000023767(TRAPPC9) ENSMUSG00000047921(Trappc9) ENSG00000167632(TRAPPC9) DRSC02706 E -0.976472991 -0.828942793 0.803203958 1.592045874 -0.252788745 0.320603406 FBgn0033170 sPLA2 secretory Phospholipase A2 http://flybase.net/reports/FBgn0033170.html protein_coding_gene "0004623=phospholipase A2 activity, 0047498=calcium-dependent phospholipase A2 activity, 0005509=calcium ion binding" "0006644=phospholipid metabolic process, 0016042=lipid catabolic process" "sPLA[[2]], secretory phospholipase A[[2]], secreted phospholipase A2, CG11124, CG14507" "IPR001211=Phospholipase A2, IPR016090=Phospholipase A2 domain, IPR013090=Phospholipase A2, active site" CG11124 16-Dec-15 2015_12 ENSDARG00000069823(LOC100149324) "ENSXETG00000019260(PROCA1),ENSXETG00000016153(PLA2G3)" embryonic stage -- adult stage organism

viable FBgn0000906 fs(1)M116 female sterile (1) M116 http://flybase.net/reports/FBgn0000906.html gene 16-Dec-15 2015_12 egg FBgn0039481 Cpr97Eb Cuticular protein 97Eb http://flybase.net/reports/FBgn0039481.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG15884, CT33880, Cuticle protein-like" IPR000618=Insect cuticle protein CG15884 16-Dec-15 2015_12 "visible,lethal,viable" wing FBgn0265903 CR44692 http://flybase.net/reports/FBgn0265903.html non_protein_coding_gene CR44692 16-Dec-15 2015_12 FBgn0039855 CG1638 http://flybase.net/reports/FBgn0039855.html protein_coding_gene 0047617=acyl-CoA hydrolase activity bs31f06.y1 IPR029069=HotDog domain CG1638 16-Dec-15 2015_12 "ENSDARG00000058352(acot9),ENSDARG00000058390(zgc:123262)" "WBGene00019015(F57F4.1),WBGene00020311(T07D3.9)" ENSXETG00000006223(ACOT9) "ENSMUSG00000025287(Acot9),ENSMUSG00000047565(Acot10)" ENSG00000123130(ACOT9) "viable,fertile" FBgn0005070 fs(2)OW211 female sterile (2) OW211 http://flybase.net/reports/FBgn0005070.html gene 16-Dec-15 2015_12 FBgn0085760 CR40641 http://flybase.net/reports/FBgn0085760.html FBan0040641 rRNA_gene CR40641 16-Dec-15 2015_12 FBgn0266330 CR44995 http://flybase.net/reports/FBgn0266330.html non_protein_coding_gene CR44995 16-Dec-15 2015_12 FBgn0267330 KdelR KDEL receptor http://flybase.net/reports/FBgn0267330.html "FBgn0014230, FBgn0022268, FBgn0025374, FBgn0025713" protein_coding_gene 0005046=KDEL sequence binding "0006890=retrograde vesicle-mediated transport, Golgi to ER, 0006621=protein retention in ER lumen" "0016021=integral component of membrane, 0030140=trans-Golgi network transport vesicle, 0005783=endoplasmic reticulum" "l(2)k00311, ERD2, lethal (2) 31Em, l(2)31Em, ER lumen protein retaining receptor 2, dmErd2, BEST:CK00230, CG5183, Erd2, KDEL-receptor, CK00230" IPR000133=ER lumen protein retaining receptor CG5183 16-Dec-15 2015_12 "ENSDARG00000005254(kdelr2),ENSDARG00000037361(kdelr2l)" YBL040C(ERD2) "WBGene00001331(erd-2),WBGene00016195(C28H8.4)" "ENSXETG00000010606(kdelr1),ENSXETG00000027589(kdelr2)" "ENSMUSG00000002778(Kdelr1),ENSMUSG00000079111(Kdelr2)" "ENSG00000105438(KDELR1),ENSG00000136240(KDELR2)" FBgn0031484 CG3165 http://flybase.net/reports/FBgn0031484.html protein_coding_gene 0003676=nucleic acid binding IPR012337=Ribonuclease H-like domain CG3165 16-Dec-15 2015_12 "ENSMUSG00000031372(Trex2),ENSMUSG00000049734(Trex1)" "ENSG00000183479(TREX2),ENSG00000213689(TREX1)" viable FBgn0010782 l(3)02521 lethal (3) 02521 http://flybase.net/reports/FBgn0010782.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069399 KH6 KH6 http://flybase.net/reports/FBgn0069399.html gene 0016063=rhodopsin biosynthetic process 16-Dec-15 2015_12 FBgn0266179 CR44885 http://flybase.net/reports/FBgn0266179.html non_protein_coding_gene CR44885 16-Dec-15 2015_12 FBgn0267150 CR45590 http://flybase.net/reports/FBgn0267150.html non_protein_coding_gene CR45590 16-Dec-15 2015_12 FBgn0019748 l(1)815-9 lethal (1) 815-9 http://flybase.net/reports/FBgn0019748.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004549 l(4)102CDu lethal (4) 102CDu http://flybase.net/reports/FBgn0004549.html gene l(4)36 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0051533 CG31533 http://flybase.net/reports/FBgn0051533.html "FBgn0045282, FBgn0045773, FBgn0064991" protein_coding_gene "NEST:bs16a07, BcDNA:AT30147, BEST:LP07046" CG31533 16-Dec-15 2015_12 viable FBgn0000391 cui curvi http://flybase.net/reports/FBgn0000391.html gene curved 16-Dec-15 2015_12 visible wing FBgn0035557 CG11353 http://flybase.net/reports/FBgn0035557.html FBgn0046438 protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" anon-WO0172774.162 "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG11353 16-Dec-15 2015_12 viable FBgn0001012 fs(3)A3 female sterile (3) A3 http://flybase.net/reports/FBgn0001012.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0035807 CG7492 http://flybase.net/reports/FBgn0035807.html FBgn0025279 protein_coding_gene "PIF-like gene 4, DPLG4, anon-EST:fe1A11, anon-fast-evolving-1A11" IPR027806=Harbinger transposase-derived nuclease domain CG7492 16-Dec-15 2015_12 "ENSDARG00000043167(LOC100329261),ENSDARG00000071407,ENSDARG00000039687(zgc:194221),ENSDARG00000068405(LOC100149584),ENSDARG00000069964,ENSDARG00000069799,ENSDARG00000070301,ENSDARG00000069661,ENSDARG00000069697" "viable,fertile" FBgn0065539 l(2)SH1067 lethal (2) SH1067 http://flybase.net/reports/FBgn0065539.html gene l(2)SH2 1067 16-Dec-15 2015_12 "lethal,recessive" FBgn0265149 CR44218 http://flybase.net/reports/FBgn0265149.html non_protein_coding_gene CR44218 16-Dec-15 2015_12 FBgn0069225 gl(2R)14-22 gl(2R)14-22 http://flybase.net/reports/FBgn0069225.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic abdominal segment,germline clone,maternal effect" FBgn0013232 E(var)183 E(var)183 http://flybase.net/reports/FBgn0013232.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0015008 Actn3 ë± actinin 3 http://flybase.net/reports/FBgn0015008.html FBgn0038459 protein_coding_gene "0003779=actin binding, 0005509=calcium ion binding, 0051015=actin filament binding" 0051017=actin filament bundle assembly "alpha-actinin-like, acta-3, alpha-actinin3, CG8953, open reading frame 1, ORF1, dabp" IPR001715=Calponin homology domain CG8953 16-Dec-15 2015_12 ENSG00000214872(SMTNL1) viable FBgn0044124 E(rst)B47 E(rst)B47 http://flybase.net/reports/FBgn0044124.html gene 0001745=compound eye morphogenesis B47 16-Dec-15 2015_12 viable FBgn0001818 l(1)P3 lethal (1) P3 http://flybase.net/reports/FBgn0001818.html gene 16-Dec-15 2015_12 lethal FBgn0019730 l(1)XR49 lethal (1) XR49 http://flybase.net/reports/FBgn0019730.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010054 JmA Ju myoA http://flybase.net/reports/FBgn0010054.html gene "A, Jm A" 16-Dec-15 2015_12 aging defective FBgn0030791 CG9132 http://flybase.net/reports/FBgn0030791.html FBgn0052566 protein_coding_gene 0006897=endocytosis 0016020=membrane CG32566 "IPR012466=Adaptin ear-binding coat-associated protein 1 NECAP-1, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG9132 16-Dec-15 2015_12 ENSDARG00000020798(zgc:73124) WBGene00022453(Y110A2AR.3) ENSXETG00000013418(NECAP2) "ENSMUSG00000028923(Necap2),ENSMUSG00000030327(Necap1)" "ENSG00000089818(NECAP1),ENSG00000157191(NECAP2)" "viable,fertile" FBgn0038238 CG14854 http://flybase.net/reports/FBgn0038238.html protein_coding_gene CG14854 16-Dec-15 2015_12 viable FBgn0266226 CR44921 http://flybase.net/reports/FBgn0266226.html non_protein_coding_gene CR44921 16-Dec-15 2015_12 FBgn0003910 tyr1 tyrosine 1 http://flybase.net/reports/FBgn0003910.html gene "Tyrosinase, tyrosinase-1, tyrosinase, tyr-1" 16-Dec-15 2015_12 "visible,recessive,viable,fertile,body color defective" "adult,macrochaeta" FBgn0040465 Dlip3 Dorsal interacting protein 3 http://flybase.net/reports/FBgn0040465.html "FBgn0034302, FBgn0062195" protein_coding_gene "0042803=protein homodimerization activity, 0001099=basal RNA polymerase II transcription machinery binding, 0005515=protein binding, 0003677=DNA binding, 0003713=transcription coactivator activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0007469=antennal development, 0006955=immune response, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0045316=negative regulation of compound eye photoreceptor development, 0009953=dorsal/ventral pattern formation, 0042480=negative regulation of eye photoreceptor cell development, 0045893=positive regulation of transcription, DNA-templated" "0000228=nuclear chromosome, 0016604=nuclear body, 0005634=nucleus" "dorsal interacting protein 3, dip3, Dip3, CG12767, anon-WO0118547.169" "IPR004210=BESS motif, IPR006578=MADF domain" CG12767 16-Dec-15 2015_12 "partially lethal - majority die,some die during embryonic stage,visible,increased cell death,viable,partially lethal - majority live,fertile,immune response defective" "embryonic/larval cuticle | embryonic stage,rhabdomerehs.2sev,ommatidium,eye photoreceptor cell,cone cell,supernumerary,primary pigment cell,eye,crossvein,wing vein,cell non-autonomous,somatic clone,embryonic/larval cuticle" FBgn0260223 CG42497 http://flybase.net/reports/FBgn0260223.html protein_coding_gene Dromel_CG9878_FBtr0071676_tim10_uORF CG42497 16-Dec-15 2015_12 FBgn0001363 l(1)1Fb lethal (1) 1Fb http://flybase.net/reports/FBgn0001363.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037661 Ada Adenosine deaminase http://flybase.net/reports/FBgn0037661.html protein_coding_gene 0004000=adenosine deaminase activity "0043103=hypoxanthine salvage, 0046103=inosine biosynthetic process, 0006154=adenosine catabolic process" 0005829=cytosol "CG11994, ada, dADA, DmADA, unnamed, ADA, DrosADA" IPR001365=Adenosine/AMP deaminase domain CG11994 16-Dec-15 2015_12 "ENSDARG00000057044,ENSDARG00000012986(adal)" YNL141W(AAH1) WBGene00016632(C44B7.12) ENSXETG00000020337(ADAL) ENSMUSG00000027259(Adal) ENSG00000168803(ADAL) viable FBgn0265674 CR44481 http://flybase.net/reports/FBgn0265674.html non_protein_coding_gene lincRNA.114 CR44481 16-Dec-15 2015_12 FBgn0051674 CG31674 http://flybase.net/reports/FBgn0051674.html FBgn0032890 protein_coding_gene "0030267=glyoxylate reductase (NADP) activity, 0051287=NAD binding" 0055114=oxidation-reduction process CG9332 "IPR006139=D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040=NAD(P)-binding domain, IPR029753=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG31674 16-Dec-15 2015_12 YNL274C(GOR1) ENSG00000137106(GRHPR) "viable,fertile" FBgn0065722 l(2)SH0567 lethal (2) SH0567 http://flybase.net/reports/FBgn0065722.html gene l(2)SH2 0567 16-Dec-15 2015_12 "lethal,recessive" FBgn0024663 l(2)k06106 lethal (2) k06106 http://flybase.net/reports/FBgn0024663.html gene 61/6 16-Dec-15 2015_12 "lethal,recessive" FBgn0035379 spz5 spatzle 5 http://flybase.net/reports/FBgn0035379.html protein_coding_gene "0005121=Toll binding, 0008083=growth factor activity" "0008045=motor neuron axon guidance, 0031637=regulation of neuronal synaptic plasticity in response to neurotrophin, 0008063=Toll signaling pathway, 0007411=axon guidance, 0021556=central nervous system formation, 0007399=nervous system development, 0010941=regulation of cell death" 0005576=extracellular region "CT28115, CG9972, NT2, DNT2, Spz5" IPR029034=Cystine-knot cytokine CG9972 16-Dec-15 2015_12 "decreased cell death,fertile,viable,increased cell death,neuroanatomy defective" "intersegmental nerve branch ISNb of A1-7,intersegmental nerve branch ISNd of A1-7,segmental nerve branch SNa of A1-7" FBgn0263079 CG43338 http://flybase.net/reports/FBgn0263079.html "FBgn0263043, FBgn0051790, FBgn0032695, FBgn0261350, FBgn0086682" protein_coding_gene "CG31790, CG42627, CG15165" CG43338 16-Dec-15 2015_12 ENSMUSG00000019767(Gm221) ENSG00000120262(C6orf97) FBgn0035491 Dpy-30L2 Dpy-30-like 2 http://flybase.net/reports/FBgn0035491.html protein_coding_gene 0030317=sperm motility "CG11591, Dpy-30L2, Dpy-30-like 2, dpy-30L2" IPR007858=Dpy-30 motif CG11591 16-Dec-15 2015_12 ENSXETG00000008549(TEgg039d20.1) ENSMUSG00000024067(Dpy30) ENSG00000162961(DPY30) "viable,male sterile" spermatozoon FBgn0013560 l(3)ry69 lethal (3) ry69 http://flybase.net/reports/FBgn0013560.html gene l(3)69 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005106 gusE gustatory E http://flybase.net/reports/FBgn0005106.html gene 0030536=larval feeding behavior 16-Dec-15 2015_12 "taste perception defective,cold sensitive" FBgn0001978 stc shuttle craft http://flybase.net/reports/FBgn0001978.html FBgn0065412 protein_coding_gene "0008270=zinc ion binding, 0003697=single-stranded DNA binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007399=nervous system development, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "l(2)35Cb, l(2)br33, BcDNA:LD22726, BG:DS04929.4, Cf4, BcDNA.LD22726, br33, shuttlecraft, SHUTTLECRAFT, l35Cb, 151662_s_at, l(2)SH2 1565, Chorion-factor-4, CG3647, l(2)SH1565, LD22726" "IPR019786=Zinc finger, PHD-type, conserved site, IPR001374=R3H domain, IPR000967=Zinc finger, NF-X1-type, IPR001841=Zinc finger, RING-type" CG3647 16-Dec-15 2015_12 YNL023C(FAP1) WBGene00007048(tag-182) ENSXETG00000014997(NFX1) ENSMUSG00000028423(Nfx1) ENSG00000086102(NFX1) " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

embryonic stage | stage 13-17 " embryonic central nervous system | restricted

, larval brain | restricted

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,maternal effect,viable,short lived,female limited" "embryonic/first instar larval cuticle,maternal effect,denticle belt,intersegmental nerve,abdominal segmental nerve,ventral nerve cord,ventral nerve cord & abdominal segment 4 | maternal effect,ventral nerve cord & abdominal segment 5 | maternal effect,ventral nerve cord & abdominal segment 6 | maternal effect,ventral nerve cord & abdominal segment 7 | maternal effect,ventral nerve cord & abdominal segment 8 | maternal effect,presumptive embryonic/larval central nervous system,central nervous system" FBgn0267937 CR46217 http://flybase.net/reports/FBgn0267937.html non_protein_coding_gene lincRNA.761 CR46217 16-Dec-15 2015_12 FBgn0069401 KH4 KH4 http://flybase.net/reports/FBgn0069401.html gene 0016063=rhodopsin biosynthetic process 16-Dec-15 2015_12 FBgn0002807 ms(1)20Ab male sterile (1) 20Ab http://flybase.net/reports/FBgn0002807.html gene "ms(1)20B, ms(1)A" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0029134 Prosë_5 Proteasome ë_5 subunit http://flybase.net/reports/FBgn0029134.html "FBgn0033553, FBgn0062234" protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0008283=cell proliferation, 0051297=centrosome organization, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization, 0022008=neurogenesis" "0000502=proteasome complex, 0005654=nucleoplasm, 0005839=proteasome core complex, 0019774=proteasome core complex, beta-subunit complex, 0005829=cytosol" "CG12323, PSMB5, LD08717, beta-5, Prosbeta5, Beta-5, dbeta5, anon-WO0118547.116, beta5, 20S proteasome, Pros b5" "IPR023333=Proteasome B-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR016050=Proteasome beta-type subunit, conserved site, IPR001353=Proteasome, subunit alpha/beta, IPR000243=Peptidase T1A, proteasome beta-subunit" CG12323 16-Dec-15 2015_12 ENSDARG00000038723(LOC100331926) YPR103W(PRE2) WBGene00003951(pbs-5) ENSXETG00000026351() "ENSMUSG00000022193(Psmb5),ENSMUSG00000024338(Psmb8)" "ENSG00000100804(PSMB5),ENSG00000206298,ENSG00000204264(PSMB8),ENSG00000206234" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC07517 IEK -1.584937565 -2.414805182 -2.633388909 -2.372843508 1.509430394 1.131208971 FBgn0265709 CR44516 http://flybase.net/reports/FBgn0265709.html non_protein_coding_gene "incRNA.441, lincRNA.441" CR44516 16-Dec-15 2015_12 FBgn0259377 EP-429 http://flybase.net/reports/FBgn0259377.html gene 16-Dec-15 2015_12 visible wing FBgn0261448 su(rdgA)40 http://flybase.net/reports/FBgn0261448.html gene su(40) 16-Dec-15 2015_12 FBgn0053703 CG33703 http://flybase.net/reports/FBgn0053703.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33703 16-Dec-15 2015_12 FBgn0033685 OSCP1 Organic solute carrier partner 1 http://flybase.net/reports/FBgn0033685.html protein_coding_gene 0042803=protein homodimerization activity 0042384=cilium assembly "0005737=cytoplasm, 0005739=mitochondrion, 0005783=endoplasmic reticulum, 0005634=nucleus, 0005886=plasma membrane, 0005794=Golgi apparatus" "dOSCP1, CG13178" IPR019332=Organic solute carrier protein 1 CG13178 16-Dec-15 2015_12 WBGene00019996(R10F2.5) ENSXETG00000005258(BC079959.1) viable FBgn0011525 l(3)rP047 lethal (3) rP047 http://flybase.net/reports/FBgn0011525.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031374 CG7337 http://flybase.net/reports/FBgn0031374.html protein_coding_gene 0005515=protein binding 0007052=mitotic spindle organization 0000922=spindle pole Q0E8U7_DROME "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG7337 16-Dec-15 2015_12 "ENSDARG00000060312(si:ch211-152c12.2),ENSDARG00000033837" viable DRSC00081 K -1.267318624 -0.276615726 0.345236554 -0.186662664 0.760361489 1.941071617 FBgn0267298 CR45734 http://flybase.net/reports/FBgn0267298.html non_protein_coding_gene CR45734 16-Dec-15 2015_12 FBgn0052126 tRNA:CR32126 transfer RNA:CR32126 http://flybase.net/reports/FBgn0052126.html FBgn0060124 tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:P:AGG:AE002602-c, chr3L.trna24-ProAGG, AE002602.trna18-ProAGG, CR32126" CR32126 16-Dec-15 2015_12 FBgn0017371 l(2)C54 lethal (2) C54 http://flybase.net/reports/FBgn0017371.html gene C54 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0024995 CG2680 http://flybase.net/reports/FBgn0024995.html protein_coding_gene "0004721=phosphoprotein phosphatase activity, 0016791=phosphatase activity" 0006470=protein dephosphorylation 0005829=cytosol "3218519, EG:100G10.4, Phos2680" "IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR023215=Nitrophenylphosphatase-like domain, IPR023214=HAD-like domain" CG2680 16-Dec-15 2015_12 viable FBgn0038902 CG6800 http://flybase.net/reports/FBgn0038902.html FBgn0043015 protein_coding_gene "0005524=ATP binding, 0004693=cyclin-dependent protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation "AC014407, CDK7-like" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG6800 16-Dec-15 2015_12 ENSDARG00000003867(zgc:101530) WBGene00010349(H01G02.2) ENSMUSG00000021483(Cdk20) viable FBgn0262532 CR43086 http://flybase.net/reports/FBgn0262532.html pseudogene_attribute CR43086 16-Dec-15 2015_12 FBgn0065280 l(2)SH2036 lethal (2) SH2036 http://flybase.net/reports/FBgn0065280.html gene l(2)SH2 2036 16-Dec-15 2015_12 "lethal,recessive" FBgn0028304 l(1)G0378 lethal (1) G0378 http://flybase.net/reports/FBgn0028304.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0067873 Mod(Prat:bw)3-2 Mod(Prat:bw)3-2 http://flybase.net/reports/FBgn0067873.html gene Mod-3-2 16-Dec-15 2015_12 "lethal,recessive" FBgn0045477 Gr64c Gustatory receptor 64c http://flybase.net/reports/FBgn0045477.html "FBgn0035485, FBgn0052256, FBgn0063609" protein_coding_gene "0033041=sweet taste receptor activity, 0008527=taste receptor activity" "0050912=detection of chemical stimulus involved in sensory perception of taste, 0050916=sensory perception of sweet taste, 0050909=sensory perception of taste" 0016021=integral component of membrane "CG14986, gr64c, Dmel64c, Gr64, GR64c, CG32256" IPR009318=Gustatory receptor CG32256 16-Dec-15 2015_12 WBGene00001804(gur-3) taste perception defective FBgn0003304 rvn ravenoid http://flybase.net/reports/FBgn0003304.html gene raven 16-Dec-15 2015_12 FBgn0036932 CG14184 http://flybase.net/reports/FBgn0036932.html FBgn0061808 protein_coding_gene "0001919=regulation of receptor recycling, 0071230=cellular response to amino acid stimulus, 0032439=endosome localization, 0042632=cholesterol homeostasis, 0032008=positive regulation of TOR signaling, 0007040=lysosome organization, 0043410=positive regulation of MAPK cascade" 0071986=Ragulator complex "dp18, p18, anon-WO0118547.633" "IPR028209=LAMTOR1/MEH1, IPR026310=LAMTOR1-like" CG14184 16-Dec-15 2015_12 ENSXETG00000024963(BC064269.1) ENSMUSG00000030842(2400001E08Rik) ENSG00000149357(LAMTOR1) viable FBgn0259539 B0821 http://flybase.net/reports/FBgn0259539.html gene 16-Dec-15 2015_12 lethal "wing,macrochaeta,unguis,pretarsus" FBgn0260229 CG42503 http://flybase.net/reports/FBgn0260229.html protein_coding_gene 0006777=Mo-molybdopterin cofactor biosynthetic process 0005829=cytosol Dromel_CG10238_FBtr0084782_mocs2_uORF "IPR012675=Beta-grasp domain, IPR016155=Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp, IPR028887=Molybdopterin synthase sulfur carrier subunit, IPR003749=ThiamineS/Molybdopterin converting factor subunit 1, IPR010034=Molybdopterin converting factor, subunit 1" CG42503 16-Dec-15 2015_12 WBGene00019633(K10D2.7) FBgn0002761 mit(1)11 mitotic 11 http://flybase.net/reports/FBgn0002761.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0039844 CG1607 http://flybase.net/reports/FBgn0039844.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport 0016020=membrane Cg1607 IPR002293=Amino acid/polyamine transporter I CG1607 16-Dec-15 2015_12 "YGR055W(MUP1),YHL036W(MUP3)" "WBGene00000002(aat-1),WBGene00000004(aat-3)" "ENSXETG00000016585(),ENSXETG00000014603(slc7a8)" "ENSMUSG00000022180(Slc7a8),ENSMUSG00000030495(Slc7a10),ENSMUSG00000040010(Slc7a5)" "ENSG00000092068(SLC7A8),ENSG00000130876(SLC7A10)" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0010035 Est-20 Esterase 20 http://flybase.net/reports/FBgn0010035.html gene 0052689=carboxylic ester hydrolase activity 16-Dec-15 2015_12 FBgn0010787 l(3)02732 lethal (3) 02732 http://flybase.net/reports/FBgn0010787.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040715 CG15386 http://flybase.net/reports/FBgn0040715.html protein_coding_gene IPR027896=Protein of unknown function DUF4574 CG15386 16-Dec-15 2015_12 FBgn0004122 l(2)43Ba lethal (2) 43Ba http://flybase.net/reports/FBgn0004122.html gene 43Ba 16-Dec-15 2015_12 lethal FBgn0028573 prc pericardin http://flybase.net/reports/FBgn0028573.html "FBgn0025696, FBgn0036231" protein_coding_gene "0007507=heart development, 0035088=establishment or maintenance of apical/basal cell polarity, 0007508=larval heart development, 0002009=morphogenesis of an epithelium, 0016477=cell migration, 0061343=cell adhesion involved in heart morphogenesis" "0005605=basal lamina, 0005578=proteinaceous extracellular matrix" "PRC, EC11, pericardin, CG5700, pc, Prc, BEST:CK01593, PC, unnamed, Pc, CK01593, Pericardin" IPR009765=Pericardin-like prepeat CG5700 16-Dec-15 2015_12 ENSG00000129646(QRICH2) "viable,fertile,short lived,cell shape defective" "embryonic pericardial cell,cardioblast,embryonic dorsal vessel,embryonic/larval heart,embryonic/larval pericardial cell,embryonic/larval cardial cell,embryonic/larval alary muscle,embryonic/larval heart | third instar larval stage,embryonic/larval pericardial cell | third instar larval stage" FBgn0263987 spoon spoonbill http://flybase.net/reports/FBgn0263987.html "FBgn0082162, FBgn0029764, FBgn0047280" protein_coding_gene "0003723=RNA binding, 0051018=protein kinase A binding" "0006099=tricarboxylic acid cycle, 0006403=RNA localization, 0008298=intracellular mRNA localization, 0007298=border follicle cell migration, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0051276=chromosome organization, 0007616=long-term memory, 0060269=centripetally migrating follicle cell migration, 0046843=dorsal appendage formation, 0030837=negative regulation of actin filament polymerization, 0040040=thermosensory behavior, 0008070=maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded, 0008104=protein localization" "0005794=Golgi apparatus, 0005739=mitochondrion" "PKAAP, PKA anchor protein, AKAP Yu, CG3249, BcDNA:GM04319, yu, Yu, DAKAP550" "IPR004087=K Homology domain, IPR002999=Tudor domain, IPR004088=K Homology domain, type 1" CG3249 16-Dec-15 2015_12 ENSDARG00000006062(akap1b) ENSMUSG00000018428(Akap1) ENSG00000121057(AKAP1) FBgn0265672 CR44479 http://flybase.net/reports/FBgn0265672.html non_protein_coding_gene lincRNA.113 CR44479 16-Dec-15 2015_12 FBgn0061098 l(3)S009647 lethal (3) S009647 http://flybase.net/reports/FBgn0061098.html gene 0096/47 16-Dec-15 2015_12 "lethal,recessive" FBgn0036020 CG8336 http://flybase.net/reports/FBgn0036020.html protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding" "IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR013026=Tetratricopeptide repeat-containing domain, IPR029000=Cyclophilin-like domain, IPR011990=Tetratricopeptide-like helical domain" CG8336 16-Dec-15 2015_12 ENSDARG00000038835(ppid) YLR216C(CPR6) ENSXETG00000019484(ppid) ENSMUSG00000027804(Ppid) ENSG00000171497(PPID) viable FBgn0262654 l(3)ED220-2 http://flybase.net/reports/FBgn0262654.html gene 16-Dec-15 2015_12 "lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,lethal" FBgn0028108 l(3)S069605a lethal (3) S069605a http://flybase.net/reports/FBgn0028108.html gene l(3)S069605 16-Dec-15 2015_12 FBgn0267929 CR46210 http://flybase.net/reports/FBgn0267929.html non_protein_coding_gene lincRNA.63 CR46210 16-Dec-15 2015_12 FBgn0060627 l(3)S087113b lethal (3) S087113b http://flybase.net/reports/FBgn0060627.html gene 0871/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0266248 CR44943 http://flybase.net/reports/FBgn0266248.html non_protein_coding_gene lincRNA.780 CR44943 16-Dec-15 2015_12 FBgn0019774 l(1)37 lethal (1) 37 http://flybase.net/reports/FBgn0019774.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0014308 l(3)neo64 lethal (3) neo64 http://flybase.net/reports/FBgn0014308.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062659 EP3263 EP3263 http://flybase.net/reports/FBgn0062659.html gene EP(3)3263 16-Dec-15 2015_12 FBgn0020580 anon-59Ce anon-59Ce http://flybase.net/reports/FBgn0020580.html gene 16-Dec-15 2015_12 FBgn0259645 B0968 http://flybase.net/reports/FBgn0259645.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "antennal segment,tarsal segment,unguis,arista" FBgn0004064 Bsg95C Blastoderm-specific transcript 95C http://flybase.net/reports/FBgn0004064.html gene bsg95C 16-Dec-15 2015_12 FBgn0011787 mRpL12 mitochondrial ribosomal protein L12 http://flybase.net/reports/FBgn0011787.html "FBgn0011362, FBgn0011514, FBgn0035940, FBgn0061393" protein_coding_gene "0003735=structural constituent of ribosome, 0003682=chromatin binding" "0006412=translation, 0016049=cell growth, 0007005=mitochondrion organization" "0005811=lipid particle, 0005763=mitochondrial small ribosomal subunit, 0005739=mitochondrion, 0005762=mitochondrial large ribosomal subunit" "L7/12A, Mrp17, CG5012, L7, L7/L12, mitochondrial ribosomal protein L7/L12, BcDNA:RE53508, l(3)rL424, l(3)j4B2, Mitochondrial ribosomal protein L5/L17, l(3)10534, mRpL7-L12" "IPR008932=Ribosomal protein L7/L12, oligomerisation, IPR013823=Ribosomal protein L7/L12, C-terminal, IPR014719=Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like, IPR000206=Ribosomal protein L7/L12" CG5012 16-Dec-15 2015_12 ENSDARG00000038768(mrpl12) YGL068W(MNP1) WBGene00012361(W09D10.3) ENSXETG00000025483(mrlp12) ENSMUSG00000039640(Mrpl12) ENSG00000183093 "lethal,recessive,small body,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,cell autonomous,somatic clone,viable,visible" "mitochondrion | somatic clone,trichogen cell" DRSC10467 K 0.709586538 0.6313913 -0.005328982 0.212731362 1.869371354 0.606807903 FBgn0034808 CG9896 http://flybase.net/reports/FBgn0034808.html protein_coding_gene CG9896 16-Dec-15 2015_12 WBGene00016809(C50D2.6) "viable,fertile" DRSC04594 K 1.133703707 -0.26794073 0.004146416 -0.038912401 -1.81523824 -0.261263633 FBgn0266924 T:nls-Ude nuclear localisation signal of Ude http://flybase.net/reports/FBgn0266924.html engineered_tag 16-Dec-15 2015_12 FBgn0261996 CG42814 http://flybase.net/reports/FBgn0261996.html "FBgn0051063, FBan0031063, FBgn0039496" protein_coding_gene "0046872=metal ion binding, 0016818=hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" "CG31063, CG6001" "IPR000086=NUDIX hydrolase domain, IPR015797=NUDIX hydrolase domain-like, IPR004385=Nucleoside diphosphate pyrophosphatase" CG42814 16-Dec-15 2015_12 "viable,fertile" FBgn0013754 Bri Bri http://flybase.net/reports/FBgn0013754.html gene 16-Dec-15 2015_12 "visible,dominant" macrochaeta FBgn0052571 TwdlX TweedleX http://flybase.net/reports/FBgn0052571.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix CG32571 IPR004145=Domain of unknown function DUF243 CG32571 16-Dec-15 2015_12 FBgn0060324 l(3)S146607b lethal (3) S146607b http://flybase.net/reports/FBgn0060324.html gene 1466/07 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040564 CG12417 http://flybase.net/reports/FBgn0040564.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267735 CR46066 http://flybase.net/reports/FBgn0267735.html non_protein_coding_gene Mgn3779 CR46066 16-Dec-15 2015_12 FBgn0065071 snoRNA:Or-CD10 http://flybase.net/reports/FBgn0065071.html FBgn0053663 snoRNA_gene 0005730=nucleolus "snoR284, chrX:6376887..6376991, Dm-284, DmOr_cd10(SnoR284), snoRNA:284, CR33663" CR33663 16-Dec-15 2015_12 FBgn0260325 GSd303 http://flybase.net/reports/FBgn0260325.html gene 16-Dec-15 2015_12 lethal FBgn0265464 Traf6 TNF-receptor-associated factor 6 http://flybase.net/reports/FBgn0265464.html "FBgn0026318, FBgn0084488" protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0010508=positive regulation of autophagy, 0007165=signal transduction, 0008219=cell death, 0008063=Toll signaling pathway, 0000209=protein polyubiquitination, 0043122=regulation of I-kappaB kinase/NF-kappaB signaling, 0045087=innate immune response, 0007391=dorsal closure, 0050829=defense response to Gram-negative bacterium, 0045746=negative regulation of Notch signaling pathway, 0006952=defense response, 0031098=stress-activated protein kinase signaling cascade, 0050688=regulation of defense response to virus" 0005737=cytoplasm "TRAF, dtraf2, traf2, CG10961, dTraf2, DTRAF2, dTraf6, EP325, dTRAF6, tumor necrosis factor receptor 2, TNF-receptor-associated factor 2, Traf2, TRAF2, TRAF6, dTRAF2" "IPR013323=SIAH-type domain, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR002083=MATH/TRAF domain, IPR027139=TNF receptor-associated factor 6, IPR001841=Zinc finger, RING-type, IPR008974=TRAF-like, IPR018957=Zinc finger, C3HC4 RING-type" CG10961 16-Dec-15 2015_12 "ENSDARG00000028058(traf6),ENSDARG00000068731(si:ch211-124k10.1),ENSDARG00000022000(traf3)" ENSXETG00000007549(traf6) ENSMUSG00000027164(Traf6) ENSG00000175104(TRAF6) FBgn0002744 mib miniature bristles http://flybase.net/reports/FBgn0002744.html gene 16-Dec-15 2015_12 "visible,viable,male,male sterile,body color defective" "macrochaeta,wing,adult thorax,tergite,posterior" FBgn0266303 CR44968 http://flybase.net/reports/FBgn0266303.html non_protein_coding_gene CR44968 16-Dec-15 2015_12 FBgn0029026 l(3)77ABf lethal (3) 77ABf http://flybase.net/reports/FBgn0029026.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0052301 CG32301 http://flybase.net/reports/FBgn0052301.html FBgn0035320 protein_coding_gene 0004016=adenylate cyclase activity "0022416=chaeta development, 0006171=cAMP biosynthetic process, 0035556=intracellular signal transduction, 0007477=notum development" 0016021=integral component of membrane "CG8970, AC" "IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site" CG32301 16-Dec-15 2015_12 "viable,body color defective" "mesothoracic tergum,macrochaeta" FBgn0267472 CR45822 http://flybase.net/reports/FBgn0267472.html non_protein_coding_gene CR45822 16-Dec-15 2015_12 FBgn0033760 CG8785 http://flybase.net/reports/FBgn0033760.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport "IPR013057=Amino acid transporter, transmembrane domain" CG8785 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "WBGene00012804(Y43F4B.7),WBGene00020837(T27A1.5)" "viable,visible" trichogen cell FBgn0005164 l(2)G552 lethal (2) G552 http://flybase.net/reports/FBgn0005164.html gene 16-Dec-15 2015_12 lethal FBgn0022244 l(2)k02107a lethal (2) k02107a http://flybase.net/reports/FBgn0022244.html gene l(2)k02107 16-Dec-15 2015_12 "lethal,recessive" FBgn0053420 5SrRNA:CR33420 5SrRNA:CR33420 http://flybase.net/reports/FBgn0053420.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33420 CR33420 16-Dec-15 2015_12 FBgn0039525 CG5646 http://flybase.net/reports/FBgn0039525.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG5646 16-Dec-15 2015_12 viable FBgn0043455 CG5986 http://flybase.net/reports/FBgn0043455.html FBgn0039142 protein_coding_gene 0003723=RNA binding "0000398=mRNA splicing, via spliceosome" 0071004=U2-type prespliceosome BEST:LP03871 IPR024974=Sde2 N-terminal domain CG5986 16-Dec-15 2015_12 "visible,viable" "eye,dorsocentral bristle,scutellar bristle" FBgn0001471 l(1)8Ad lethal (1) 8Ad http://flybase.net/reports/FBgn0001471.html gene l(1)A86 16-Dec-15 2015_12 lethal FBgn0085576 CG41250 http://flybase.net/reports/FBgn0085576.html FBan0041250 protein_coding_gene 16-Dec-15 2015_12 FBgn0002608 M(2)d Minute (2) d http://flybase.net/reports/FBgn0002608.html gene 16-Dec-15 2015_12 FBgn0024331 Mdp-1 Macrophage derived proteoglycan-1 http://flybase.net/reports/FBgn0024331.html gene MDP-1 16-Dec-15 2015_12 FBgn0050082 CG30082 http://flybase.net/reports/FBgn0050082.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis CR30082 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG30082 16-Dec-15 2015_12 FBgn0014038 Su(tor)1-1 Su(tor)1-1 http://flybase.net/reports/FBgn0014038.html gene 16-Dec-15 2015_12 female sterile FBgn0265807 CR44596 http://flybase.net/reports/FBgn0265807.html non_protein_coding_gene lincRNA.122 CR44596 16-Dec-15 2015_12 FBgn0001027 Fs(3)Apc Female sterile (3) Apc http://flybase.net/reports/FBgn0001027.html gene "fs(3)Apc, Apc, Fs(3)Sz1" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,dominant" "egg,maternal effect,dorsal appendage" FBgn0082374 EP1547 EP1547 http://flybase.net/reports/FBgn0082374.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0065640 l(2)SH0761 lethal (2) SH0761 http://flybase.net/reports/FBgn0065640.html gene l(2)SH2 0761 16-Dec-15 2015_12 "lethal,recessive" FBgn0267609 CR45947 http://flybase.net/reports/FBgn0267609.html pseudogene_attribute CR45947 16-Dec-15 2015_12 FBgn0086031 snoRNA:Me28S-U1230 http://flybase.net/reports/FBgn0086031.html snoRNA_gene "Me28S-Um1230, CR34660" CR34660 16-Dec-15 2015_12 FBgn0046655 anon-38D.1 anon-38D.1 http://flybase.net/reports/FBgn0046655.html gene 38D.1 16-Dec-15 2015_12 FBgn0017572 Mo25 Mo25 http://flybase.net/reports/FBgn0017572.html FBgn0010713 protein_coding_gene 0001700=embryonic development via the syncytial blastoderm "0005737=cytoplasm, 0005634=nucleus" "mo25, Dmo25, dMo25, l(3)00274, CG4083" "IPR013878=Mo25-like, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG4083 16-Dec-15 2015_12 "ENSDARG00000036658(cab39l),ENSDARG00000043451(cab39),ENSDARG00000021374(cab39l1)" YKL189W(HYM1) "WBGene00019827(mop-25.1),WBGene00013140(mop-25.2)" "ENSXETG00000008260(CAB39),ENSXETG00000015659(CAB39L)" "ENSMUSG00000036707(Cab39),ENSMUSG00000021981(Cab39l)" "ENSG00000135932(CAB39),ENSG00000102547(CAB39L)" "visible,lethal,recessive,partially,rescuable maternal effect,somatic clone,lethal - all die before end of larval stage,some die during larval stage,viable,body color defective" "wing vein,embryonic/first instar larval cuticle,chaeta,somatic clone,supernumerary,wing margin,mesothoracic tergum" FBgn0065467 l(2)SH1338 lethal (2) SH1338 http://flybase.net/reports/FBgn0065467.html gene l(2)SH2 1338 16-Dec-15 2015_12 "lethal,recessive" FBgn0001258 ImpL3 Ecdysone-inducible gene L3 http://flybase.net/reports/FBgn0001258.html FBgn0035698 protein_coding_gene 0004459=L-lactate dehydrogenase activity "0007520=myoblast fusion, 0055114=oxidation-reduction process, 0019752=carboxylic acid metabolic process, 0005975=carbohydrate metabolic process, 0006096=glycolytic process, 0007525=somatic muscle development" 0005737=cytoplasm "ldh, IMP-L3, dmLDH, IMPL3, lactate dehydrogenase B, CG10160, lincRNA.S4223, Impl3, dLdha, Ld, Ecdysone-induced gene L3, lactic DH, Ldh, lactate/malate dehydrogenease, impl3, Imp-L3, LDH, dLDH, lactate dehydrogenase" "IPR015955=Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR001236=Lactate/malate dehydrogenase, N-terminal, IPR022383=Lactate/malate dehydrogenase, C-terminal, IPR011304=L-lactate dehydrogenase, IPR016040=NAD(P)-binding domain, IPR001557=L-lactate/malate dehydrogenase, IPR018177=L-lactate dehydrogenase, active site" CG10160 16-Dec-15 2015_12 "ENSDARG00000040856(ldha),ENSDARG00000071076(ldhbb),ENSDARG00000021574,ENSDARG00000019644(ldhba)" WBGene00002262(ldh-1) ENSXETG00000016974(ldhb) "ENSMUSG00000030246(Ldhb),ENSMUSG00000063229(Ldha),ENSMUSG00000030851(Ldhc)" "ENSG00000111716(LDHB),ENSG00000134333(LDHA),ENSG00000166796(LDHC),ENSG00000171989(LDHAL6B),ENSG00000166800(LDHAL6A)" " embryonic stage | stage >=15 , larval stage , embryonic stage && larval stage && adult stage " " embryonic/larval posterior spiracle

, imaginal disc

, pharyngeal muscle

, embryonic/larval proventriculus

" " prepupal stage , embryonic stage | stage >=15 , embryonic stage " " tarsal segment

, embryonic/larval posterior spiracle

, ventral thoracic disc

, pharyngeal muscle

, embryonic/larval somatic muscle

, embryonic/larval proventriculus

, tibia | presumptive

" viable "embryonic/larval somatic muscle,embryonic myoblast" DRSC11198 E 1.264845478 0.962645883 1.71608137 0.351887407 -0.146074946 0.163819377 FBgn0267977 mh maternal haploid http://flybase.net/reports/FBgn0267977.html "FBgn0030646, FBgn0002740" protein_coding_gene 0003677=DNA binding "0007067=mitotic nuclear division, 0006281=DNA repair, 0009650=UV protection" "0042585=germinal vesicle, 0001940=male pronucleus" "CG9203, fs(1)A1182, fs(1)1182, fs(1)maternal haploid" "IPR006642=Zinc finger, Rad18-type putative, IPR006640=SprT-like" CG9203 16-Dec-15 2015_12 WBGene00011834(T19B10.6) ENSXETG00000021416(C1orf124) ENSG00000010072(C1orf124) FBgn0011927 tRNA:M3:70Fa transfer RNA:met3:70Fa http://flybase.net/reports/FBgn0011927.html "FBgn0003814, FBgn0052142, FBgn0060145" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033436=AUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Met-ATG], chr3L.trna36-MetCAT, tRNA:met3:70Fa, AE002602.trna2-MetCAT, tRNA:M:CAT:AE002602-a, CR32142" CR32142 16-Dec-15 2015_12 FBgn0020641 Lcp65Ad Lcp65Ad http://flybase.net/reports/FBgn0020641.html FBgn0064917 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Lcp-d, BcDNA:LP05231, DMCLP65d, CG6955, DCP1, DmelLcp65Ad" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG6955 16-Dec-15 2015_12 " embryonic stage , pupal stage | 7-13 hr , larval stage " DRSC11211 K -0.438624407 0.595835479 0.026066446 -0.151176829 -0.014813563 2.170699421 FBgn0033380 Phax Phosphorylated adaptor for RNA export http://flybase.net/reports/FBgn0033380.html FBgn0043814 protein_coding_gene 0003723=RNA binding "0007399=nervous system development, 0006408=snRNA export from nucleus" "0005737=cytoplasm, 0005634=nucleus" "PHosphorylated Adaptor for RNA Export, BEST:GH22533, dPHAX, CG8069" "IPR019385=Phosphorylated adapter RNA export protein, RNA-binding domain" CG8069 16-Dec-15 2015_12 ENSDARG00000044298(phax) ENSXETG00000005189(PHAX) ENSMUSG00000008301(Phax) ENSG00000164902(PHAX) viable FBgn0025767 l(3)89Ci lethal (3) 89Ci http://flybase.net/reports/FBgn0025767.html gene l(3)M238 16-Dec-15 2015_12 "lethal,recessive" FBgn0084032 CG41472 http://flybase.net/reports/FBgn0084032.html FBan0041472 protein_coding_gene 16-Dec-15 2015_12 FBgn0004951 1688-10Ea 1.688 satellite-related 10Ea http://flybase.net/reports/FBgn0004951.html repeat_region "1.688, 1688-10E[d]" 16-Dec-15 2015_12 FBgn0038115 CG7966 http://flybase.net/reports/FBgn0038115.html protein_coding_gene 0008430=selenium binding "IPR015943=WD40/YVTN repeat-like-containing domain, IPR008826=Selenium-binding protein, IPR011042=Six-bladed beta-propeller, TolB-like" CG7966 16-Dec-15 2015_12 ENSDARG00000024717(selenbp1) WBGene00012538(Y37A1B.5) ENSXETG00000020722(SELENBP1) "ENSMUSG00000068874(Selenbp1),ENSMUSG00000068877(Selenbp2)" ENSG00000143416(SELENBP1) viable FBgn0263994 CG43737 http://flybase.net/reports/FBgn0263994.html "FBgn0030618, FBgn0030619" protein_coding_gene "CG15028, CG15029, Dm_X:77844" CG43737 16-Dec-15 2015_12 FBgn0025005 E(var)166-7 E(var)166-7 http://flybase.net/reports/FBgn0025005.html gene E-166/7 16-Dec-15 2015_12 FBgn0030651 CG12706 http://flybase.net/reports/FBgn0030651.html protein_coding_gene 16-Dec-15 2015_12 FBgn0020646 Lcp65Aë¬ Lcp65Aë¬ http://flybase.net/reports/FBgn0020646.html FBgn0042116 pseudogene_attribute "CR18775, Lcp-a[Psi], Lcp65APsi, LCP65Aapsi, DCP4[Psi], Lcp-Psi, CG18775, Larval cuticle protein Psi" CR18775 16-Dec-15 2015_12 FBgn0024877 l(2)52Fd lethal (2) 52Fd http://flybase.net/reports/FBgn0024877.html gene E3.27 16-Dec-15 2015_12 lethal FBgn0000848 fs(1)M36 female sterile (1) M36 http://flybase.net/reports/FBgn0000848.html gene unnamed 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0039183 Dis3 Dis3 http://flybase.net/reports/FBgn0039183.html protein_coding_gene 0000175=3'-5'-exoribonuclease activity "0006397=mRNA processing, 0022008=neurogenesis, 0010468=regulation of gene expression, 0071027=nuclear RNA surveillance" "0000177=cytoplasmic exosome (RNase complex), 0005634=nucleus, 0000176=nuclear exosome (RNase complex), 0005652=nuclear lamina" "taz, Tazman, dRrp44, dDis3, Rrp44, Dis3 ribonuclease, dis3, tazman, CG6413" "IPR022966=Ribonuclease II/R, conserved site, IPR029060=PIN domain-like, IPR002716=PIN domain, IPR012340=Nucleic acid-binding, OB-fold" CG6413 16-Dec-15 2015_12 ENSDARG00000060559(dis3) YOL021C(DIS3) WBGene00001001(dis-3) ENSXETG00000012344(DIS3) ENSMUSG00000033166(Dis3) ENSG00000083520(DIS3) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" DRSC16034 I 2.586474344 0.837758563 -0.474001732 -1.488087723 -0.888544752 0.737121566 FBgn0266752 CR45225 http://flybase.net/reports/FBgn0266752.html non_protein_coding_gene CR45225 16-Dec-15 2015_12 FBgn0033185 CG1603 http://flybase.net/reports/FBgn0033185.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction" "IPR006578=MADF domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1603 16-Dec-15 2015_12 WBGene00003380(mnm-2) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC06602 K 1.215293981 0.561216313 0.147574555 0.157335266 -2.00008282 -1.464007171 FBgn0010894 sinu sinuous http://flybase.net/reports/FBgn0010894.html FBgn0035613 protein_coding_gene "0007391=dorsal closure, 0035151=regulation of tube size, open tracheal system, 0060857=establishment of glial blood-brain barrier, 0003015=heart process, 0007424=open tracheal system development, 0061343=cell adhesion involved in heart morphogenesis, 0019991=septate junction assembly" "0005918=septate junction, 0016021=integral component of membrane, 0005886=plasma membrane" "Sinuous, CG10624, Sinu, 6524, i8, l(3)06524" IPR004031=PMP-22/EMP/MP20/Claudin superfamily CG10624 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die,visible" "embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,dorsal trunk primordium,heart primordium,septate junction,taenidial fold,presumptive embryonic/larval tracheal system,trichogen cell" FBgn0050178 CG30178 http://flybase.net/reports/FBgn0050178.html FBgn0034949 protein_coding_gene 0008270=zinc ion binding CG17263 "IPR001781=Zinc finger, LIM-type" CG30178 16-Dec-15 2015_12 WBGene00012379(Y1A5A.1) "ENSXETG00000022912(fhl3),ENSXETG00000002577(FHL2),ENSXETG00000001065(FHL5),ENSXETG00000019760(fhl1)" "ENSMUSG00000032643(Fhl3),ENSMUSG00000008136(Fhl2),ENSMUSG00000028259(Fhl5),ENSMUSG00000050035(Fhl4),ENSMUSG00000023092(Fhl1)" "ENSG00000183386(FHL3),ENSG00000115641(FHL2),ENSG00000112214(FHL5),ENSG00000022267(FHL1)" "lethal,recessive,viable" FBgn0067738 l(1)G0325 lethal (1) G0325 http://flybase.net/reports/FBgn0067738.html gene 16-Dec-15 2015_12 FBgn0035258 CG13931 http://flybase.net/reports/FBgn0035258.html protein_coding_gene CG13931 16-Dec-15 2015_12 viable FBgn0037133 CG7370 http://flybase.net/reports/FBgn0037133.html "FBgn0047265, FBgn0064946" protein_coding_gene BcDNA:GM07065 CG7370 16-Dec-15 2015_12 "viable,fertile" FBgn0265192 Snp Snipper http://flybase.net/reports/FBgn0265192.html "FBgn0265183, FBgn0259142, FBgn0034685" protein_coding_gene "0008311=double-stranded DNA 3'-5' exodeoxyribonuclease activity, 0008310=single-stranded DNA 3'-5' exodeoxyribonuclease activity, 0003676=nucleic acid binding, 0000175=3'-5'-exoribonuclease activity" 0071044=histone mRNA catabolic process "CG30327, CG42257, CG44248, CG6393, CG11478" "IPR013520=Exonuclease, RNase T/DNA polymerase III, IPR012337=Ribonuclease H-like domain" CG44248 16-Dec-15 2015_12 FBgn0014361 Mst58.1 Male-specific transcript 58.1 http://flybase.net/reports/FBgn0014361.html gene male-specific-transcript-58.1 16-Dec-15 2015_12 FBgn0082640 Pvr::Hsap\PDGFRA PGFRë± http://flybase.net/reports/FBgn0082640.html engineered_fusion_gene Pvr::Hsap\PGFRalpha 16-Dec-15 2015_12 FBgn0039536 unc80 http://flybase.net/reports/FBgn0039536.html protein_coding_gene 0005261=cation channel activity "0055080=cation homeostasis, 0045475=locomotor rhythm" 0034703=cation channel complex "CG18437, UNC80" CG18437 16-Dec-15 2015_12 WBGene00006812(unc-80) ENSXETG00000023691(UNC80) ENSMUSG00000055567(Unc80) "circadian behavior defective,viable" FBgn0035722 CG10075 http://flybase.net/reports/FBgn0035722.html protein_coding_gene 0007030=Golgi organization "IPR021150=Ubiquinol-cytochrome c chaperone/UPF0174, IPR007129=Ubiquinol-cytochrome c chaperone, CBP3" CG10075 16-Dec-15 2015_12 WBGene00016442(C35D10.5) ENSMUSG00000005882(Uqcc) ENSG00000101019(UQCC) "partially lethal - majority die,some die during pupal stage,viable" FBgn0260795 NaPi-III Na+-dependent inorganic phosphate cotransporter type III http://flybase.net/reports/FBgn0260795.html "FBgn0036137, FBgn0052078" protein_coding_gene "0015321=sodium-dependent phosphate transmembrane transporter activity, 0005315=inorganic phosphate transmembrane transporter activity, 0015114=phosphate ion transmembrane transporter activity" 0044341=sodium-dependent phosphate transport 0016020=membrane "CG42575, dPit, CR32078, CG7628, Dromel_CG7628_FBtr0076213_mORF" IPR001204=Phosphate transporter CG42575 16-Dec-15 2015_12 "ENSDARG00000060796(zgc:152990),ENSDARG00000010641(slc20a1b),ENSDARG00000020114(slc20a1a)" YBR296C(PHO89) "WBGene00015055(B0222.3),WBGene00015054(B0222.2),WBGene00017312(F09G2.3)" "ENSXETG00000009532(slc20a2),ENSXETG00000018957(slc20a1)" "ENSMUSG00000037656(Slc20a2),ENSMUSG00000027397(Slc20a1)" "ENSG00000144136(SLC20A1),ENSG00000168575(SLC20A2)" FBgn0005261 l(3)SG81 lethal (3) SG81 http://flybase.net/reports/FBgn0005261.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0004736 l(3)85Dc lethal (3) 85Dc http://flybase.net/reports/FBgn0004736.html gene 16-Dec-15 2015_12 lethal FBgn0046845 ird21 immune response deficient 21 http://flybase.net/reports/FBgn0046845.html gene 0006959=humoral immune response 16-Dec-15 2015_12 "lethal,recessive,immune response defective" FBgn0001225 Hsp26 Heat shock protein 26 http://flybase.net/reports/FBgn0001225.html FBgn0010231 protein_coding_gene 0017022=myosin binding "0009631=cold acclimation, 0008340=determination of adult lifespan, 0009408=response to heat" "0005875=microtubule associated complex, 0005737=cytoplasm" "DmHsp26, heat shock protein 26, 26K, HSP26, hsp26, small hsp locus 67B, Protein 26, hsp 26, CG4183, Hsp 26, 26, heat shock protein hsp26" "IPR008978=HSP20-like chaperone, IPR031107=Small heat shock protein HSP20, IPR002068=Alpha crystallin/Hsp20 domain, IPR001436=Alpha crystallin/Heat shock protein" CG4183 16-Dec-15 2015_12 "ENSDARG00000041065(hspb1),ENSDARG00000058362(LOC100331249),ENSDARG00000052447(cryabb),ENSDARG00000058365(hspb8)" "WBGene00004798(sip-1),WBGene00002020(hsp-16.49),WBGene00002015(hsp-16.1),WBGene00002018(hsp-16.41),WBGene00002016(hsp-16.2),WBGene00008592(F08H9.4)" " embryonic stage | early , prepupal stage " "viable,fertile,long lived,male,chemical resistant,female fertile,reduced" FBgn0063385 snoRNA:Me28S-A3407a http://flybase.net/reports/FBgn0063385.html snoRNA_gene "Me28S-A3407a, Me28S-A3407a(U29), U29snoRNA, snoRNA:U29:54Ea, CR32888" CR32888 16-Dec-15 2015_12 FBgn0010813 v(3)03699 v(3)03699 http://flybase.net/reports/FBgn0010813.html gene l(3)03699 16-Dec-15 2015_12 "viable,visible,recessive" "wing vein,posterior crossvein,tergite" FBgn0262160 CG9932 http://flybase.net/reports/FBgn0262160.html "FBgn0032469, FBgn0043346" protein_coding_gene 0046872=metal ion binding "0035220=wing disc development, 0022416=chaeta development" "elongation factor 4A, Ef4A, Elongation factor 4a, elF-4A, EP2317" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG9932 16-Dec-15 2015_12 ENSDARG00000063381 FBgn0019672 mor(1)7 mortality gene (1)7 http://flybase.net/reports/FBgn0019672.html gene 16-Dec-15 2015_12 short lived FBgn0014894 anon-10Aa anon-10Aa http://flybase.net/reports/FBgn0014894.html gene unnamed 16-Dec-15 2015_12 FBgn0267310 CR45746 http://flybase.net/reports/FBgn0267310.html non_protein_coding_gene CR45746 16-Dec-15 2015_12 FBgn0027125 l(3)IIIb lethal (3) IIIb http://flybase.net/reports/FBgn0027125.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0001418 l(1)6Db lethal (1) 6Db http://flybase.net/reports/FBgn0001418.html gene "l(1)EM24, EM24, l(1)EC224" 16-Dec-15 2015_12 lethal FBgn0020441 Est-17 Est-17 http://flybase.net/reports/FBgn0020441.html gene 0052689=carboxylic ester hydrolase activity 16-Dec-15 2015_12 FBgn0034406 Jheh3 Juvenile hormone epoxide hydrolase 3 http://flybase.net/reports/FBgn0034406.html protein_coding_gene "0004301=epoxide hydrolase activity, 0008096=juvenile hormone epoxide hydrolase activity, 0033961=cis-stilbene-oxide hydrolase activity" 0006719=juvenile hormone catabolic process 0043231=intracellular membrane-bounded organelle CG15106 "IPR016292=Epoxide hydrolase, IPR000639=Epoxide hydrolase-like, IPR010497=Epoxide hydrolase, N-terminal, IPR029058=Alpha/Beta hydrolase fold" CG15106 16-Dec-15 2015_12 ENSDARG00000042854(ephx1) WBGene00020909(W01A11.1) ENSXETG00000022654(EPHX1) ENSMUSG00000038776(Ephx1) ENSG00000143819(EPHX1) "viable,fertile" FBgn0003110 plk plucked http://flybase.net/reports/FBgn0003110.html gene 0008407=chaeta morphogenesis 16-Dec-15 2015_12 FBgn0033982 Cyp317a1 Cyp317a1 http://flybase.net/reports/FBgn0033982.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG17453, 317a1" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG17453 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0265908 CR44697 http://flybase.net/reports/FBgn0265908.html non_protein_coding_gene lincRNA.39 CR44697 16-Dec-15 2015_12 FBgn0032988 Tif-IA Tif-IA http://flybase.net/reports/FBgn0032988.html "FBan0003278, FBgn0032989, FBgn0032990" protein_coding_gene "0006356=regulation of transcription from RNA polymerase I promoter, 0042254=ribosome biogenesis" 0005736=DNA-directed RNA polymerase I complex "CG16938, CG5951, TifIA, TIf-IA, TIF-IA, CG3278, Tif-1A, tif1a, dTIF-IA, TIF-1A" IPR007991=RNA polymerase I specific transcription initiation factor RRN3 CG3278 16-Dec-15 2015_12 YKL125W(RRN3) WBGene00007980(C36E8.1) ENSXETG00000005536() ENSMUSG00000022682(Rrn3) ENSG00000085721(RRN3) "cell growth defective,somatic clone,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,partially lethal - majority die,some die during pupal stage" "female germline cell,mesothoracic tergum" DRSC03717 IE -1.606059088 0.218455113 -0.348822672 5.758255446 -0.251198359 -0.593740873 FBgn0025169 l(2)38EFb lethal (2) 38EFb http://flybase.net/reports/FBgn0025169.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0070050 3L-114-20 3L-114-20 http://flybase.net/reports/FBgn0070050.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 FBgn0265450 CR44350 http://flybase.net/reports/FBgn0265450.html non_protein_coding_gene CR44350 16-Dec-15 2015_12 FBgn0035392 CG1271 http://flybase.net/reports/FBgn0035392.html protein_coding_gene 0004370=glycerol kinase activity 0005975=carbohydrate metabolic process "IPR018484=Carbohydrate kinase, FGGY, N-terminal, IPR000577=Carbohydrate kinase, FGGY, IPR018485=Carbohydrate kinase, FGGY, C-terminal, IPR018483=Carbohydrate kinase, FGGY, conserved site" CG1271 16-Dec-15 2015_12 ENSDARG00000062864 WBGene00016939(C55B6.1) ENSXETG00000023572(GK5) ENSMUSG00000041440(Gk5) ENSG00000175066(GK5) viable FBgn0042640 fz::fz2 fz::fz2 http://flybase.net/reports/FBgn0042640.html engineered_fusion_gene 16-Dec-15 2015_12 "planar polarity defective,cell non-autonomous,visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing hair,cell non-autonomous,unguis,wing margin bristle,ectopic,wing,wing margin,mesothoracic tergum,leg,distal,ommatidium" FBgn0267680 CR46016 http://flybase.net/reports/FBgn0267680.html non_protein_coding_gene CR46016 16-Dec-15 2015_12 FBgn0016868 l(2)39Aa lethal (2) 39Aa http://flybase.net/reports/FBgn0016868.html "FBgn0016869, FBgn0016870" gene "l(2)39Ab, l(2)39Ac" 16-Dec-15 2015_12 lethal FBgn0001190 Hg Hang glider http://flybase.net/reports/FBgn0001190.html gene 16-Dec-15 2015_12 visible wing FBgn0014921 anon-72ABe anon-72ABe http://flybase.net/reports/FBgn0014921.html gene 16-Dec-15 2015_12 FBgn0001152 gt-4 giant 4 http://flybase.net/reports/FBgn0001152.html gene gt4 16-Dec-15 2015_12 "visible,viable,reduced" FBgn0016023 l(3)87Em lethal (3) 87Em http://flybase.net/reports/FBgn0016023.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260367 GSd426 http://flybase.net/reports/FBgn0260367.html gene 16-Dec-15 2015_12 lethal FBgn0035900 ZC3H3 ZC3H3 http://flybase.net/reports/FBgn0035900.html protein_coding_gene 0046872=metal ion binding "0051168=nuclear export, 0006378=mRNA polyadenylation" "CG6694, dZC3H3" "IPR000571=Zinc finger, CCCH-type" CG6694 16-Dec-15 2015_12 ENSXETG00000004937(Q3KUR6_XENTR) "viable,fertile" DRSC10696 IEK 2.929042558 -0.507586752 2.821172069 -3.08114176 0.270020129 2.495981433 FBgn0051454 CG31454 http://flybase.net/reports/FBgn0051454.html FBgn0037593 protein_coding_gene CG11740 IPR026749=Transmembrane protein 135 CG31454 16-Dec-15 2015_12 ENSDARG00000069157(tmem135) WBGene00019345(tmem-135) ENSXETG00000010432() ENSMUSG00000039428(Tmem135) ENSG00000166575(TMEM135) "viable,fertile" FBgn0266908 CR45368 http://flybase.net/reports/FBgn0266908.html non_protein_coding_gene CR45368 16-Dec-15 2015_12 FBgn0040346 CG3704 http://flybase.net/reports/FBgn0040346.html FBgn0029546 protein_coding_gene "0017076=purine nucleotide binding, 0003924=GTPase activity" "EG:BACR7A4.17, XAB1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR004130=GPN-loop GTPase, IPR030230=GPN-loop GTPase 1" CG3704 16-Dec-15 2015_12 ENSDARG00000043928(zgc:100927) YJR072C(NPA3) WBGene00001661(gop-2) ENSMUSG00000064037(Gpn1) ENSG00000115254 "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0021936 l(2)k10825 lethal (2) k10825 http://flybase.net/reports/FBgn0021936.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262026 CG42837 http://flybase.net/reports/FBgn0262026.html protein_coding_gene 2001019=positive regulation of retrograde axon cargo transport CG8446 CG42837 16-Dec-15 2015_12 FBgn0011261 Dmnd Dimethylnitrosamine demethylase http://flybase.net/reports/FBgn0011261.html gene 0004162=dimethylnitrosamine demethylase activity 0043231=intracellular membrane-bounded organelle DMN-d 16-Dec-15 2015_12 FBgn0260250 GSd219 http://flybase.net/reports/FBgn0260250.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0031561 IM33 Immune induced molecule 33 http://flybase.net/reports/FBgn0031561.html "FBgn0047018, FBgn0047049" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0009617=response to bacterium "CT37183, BcDNA:RH38008, DIM 33, BcDNA:RH05411, CG16712" "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG16712 16-Dec-15 2015_12 ENSDARG00000069736 ENSXETG00000016886(SPINT3) "ENSMUSG00000074595(Wfdc6a),ENSMUSG00000070531(Wfdc6b),ENSMUSG00000017733(Spinlw1)" ENSG00000168630 viable DRSC24513 K -0.116440151 0.182557992 0.308400543 0.533289974 0.371570296 -2.090654865 FBgn0053667 CG33667 http://flybase.net/reports/FBgn0053667.html protein_coding_gene CG33667 16-Dec-15 2015_12 FBgn0039953 CG17668 http://flybase.net/reports/FBgn0039953.html protein_coding_gene 16-Dec-15 2015_12 FBgn0029826 CG6041 http://flybase.net/reports/FBgn0029826.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region SP86 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG6041 16-Dec-15 2015_12 viable FBgn0037931 CG18476 http://flybase.net/reports/FBgn0037931.html FBgn0037932 protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus CG17822 "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG18476 16-Dec-15 2015_12 YPR186C(PZF1) viable FBgn0002487 l(3)SG47 lethal (3) SG47 http://flybase.net/reports/FBgn0002487.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0043033 l(2)42Cb lethal (2) 42Cb http://flybase.net/reports/FBgn0043033.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264490 Eip93F Ecdysone-induced protein 93F http://flybase.net/reports/FBgn0264490.html "FBgn0013948, FBgn0038920, FBgn0066001, FBgn0013585" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0008628=hormone-mediated apoptotic signaling pathway, 0048102=autophagic cell death, 0006911=phagocytosis, engulfment, 0071456=cellular response to hypoxia, 0035096=larval midgut cell programmed cell death, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0071390=cellular response to ecdysone, 0045893=positive regulation of transcription, DNA-templated, 0035071=salivary gland cell autophagic cell death, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0006914=autophagy, 0006355=regulation of transcription, DNA-templated" "0035327=transcriptionally active chromatin, 0005634=nucleus, 0005700=polytene chromosome" "anon-WO02059370.58, psg11, unnamed, Eip93, Eip93f, l(3)ry93, l(3)93, CG18389, eip93f, E93, lincRNA.833, lethal (3) ry93, Eip93F" "IPR009057=Homeodomain-like, IPR007889=DNA binding HTH domain, Psq-type" CG18389 16-Dec-15 2015_12 " prepupal stage | early , prepupal stage | late , prepupal stage | stage P1--pupal stage | stage P7 , prepupal stage | 12 hr , pupal stage | 196 hr " " pupal/adult digestive system

, imaginal disc

, embryonic/larval salivary gland

, embryonic/larval fat body

, organism

, larval central nervous system

" FBgn0042634 l(3)S099801b lethal (3) S099801b http://flybase.net/reports/FBgn0042634.html gene "0998/01, l(3)S099801, l(3)099801" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0262781 Su(E1)-O http://flybase.net/reports/FBgn0262781.html gene 16-Dec-15 2015_12 FBgn0029647 CG17959 http://flybase.net/reports/FBgn0029647.html protein_coding_gene CG17959 16-Dec-15 2015_12 viable FBgn0263882 l(3)C10 http://flybase.net/reports/FBgn0263882.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0010038 GstD2 Glutathione S transferase D2 http://flybase.net/reports/FBgn0010038.html FBgn0038021 protein_coding_gene "0004364=glutathione transferase activity, 0004602=glutathione peroxidase activity" 0006749=glutathione metabolic process 0005737=cytoplasm "GST D2, gstd21, CG4181, GstD21, glutathione-S-transferase D2, GST-D2, Gstd21, gstd2, Glutathione S transferase D21, Gst, GST, GSTD2, DmGSTD2, gstD21, gst D21, DmGST21" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal" CG4181 16-Dec-15 2015_12 YNL229C(URE2) adult stage "viable,fertile" FBgn0052634 CG32634 http://flybase.net/reports/FBgn0052634.html FBgn0062481 protein_coding_gene BcDNA:GM08788 16-Dec-15 2015_12 FBgn0016771 anon-59Da anon-59Da http://flybase.net/reports/FBgn0016771.html gene 16-Dec-15 2015_12 FBgn0260573 MENE-LL7 http://flybase.net/reports/FBgn0260573.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0042144 CG18821 http://flybase.net/reports/FBgn0042144.html protein_coding_gene 16-Dec-15 2015_12 FBgn0070054 2L-250-35 2L-250-35 http://flybase.net/reports/FBgn0070054.html gene 0007350=blastoderm segmentation 16-Dec-15 2015_12 "embryonic segment,germline clone,maternal effect" FBgn0259557 B0457 http://flybase.net/reports/FBgn0259557.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262900 CG43255 http://flybase.net/reports/FBgn0262900.html protein_coding_gene CG43255 16-Dec-15 2015_12 FBgn0004397 Vinc Vinculin http://flybase.net/reports/FBgn0004397.html "FBgn0015840, FBgn0024918" protein_coding_gene "0003779=actin binding, 0005198=structural molecule activity, 0051015=actin filament binding" "0007155=cell adhesion, 0048812=neuron projection morphogenesis, 0007016=cytoskeletal anchoring at plasma membrane, 0006909=phagocytosis, 0007160=cell-matrix adhesion" "0015629=actin cytoskeleton, 0005925=focal adhesion" "CG3299, Vin2EF, CT11081, Vin, vinculin, EG:103B4.1, vinc, Dmvincp, Vinculin at 2EF" "IPR000633=Vinculin, conserved site, IPR006077=Vinculin/alpha-catenin, IPR017997=Vinculin" CG3299 16-Dec-15 2015_12 WBGene00000942(deb-1) ENSMUSG00000021823(Vcl) ENSG00000035403(VCL) "viable,fertile" muscle attachment site FBgn0069331 X-100-6 X-100-6 http://flybase.net/reports/FBgn0069331.html gene 0007367=segment polarity determination 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,recessive,rescuable maternal effect,some die during embryonic stage,maternal effect" "embryonic segment,germline clone,maternal effect,denticle belt,ectopic" FBgn0266139 CR44845 http://flybase.net/reports/FBgn0266139.html non_protein_coding_gene CR44845 16-Dec-15 2015_12 FBgn0033616 CG7745 http://flybase.net/reports/FBgn0033616.html protein_coding_gene IPR006578=MADF domain CG7745 16-Dec-15 2015_12 viable FBgn0030694 CG15602 http://flybase.net/reports/FBgn0030694.html protein_coding_gene "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related" CG15602 16-Dec-15 2015_12 ENSDARG00000003642(zgc:92683) WBGene00011248(R11D1.10) ENSXETG00000021564(ZFYVE19) ENSMUSG00000068580(Zfyve19) ENSG00000166140(ZFYVE19) viable DRSC19671 K 0.056750037 -0.073950304 0.951909215 -0.134260156 2.473247619 0.572435689 FBgn0039972 CG17018 http://flybase.net/reports/FBgn0039972.html "FBan0017018, FBgn0039971, FBgn0063679" protein_coding_gene 0003676=nucleic acid binding 0010468=regulation of gene expression 0005777=peroxisome "BcDNA:RE40762, CG17410" "IPR024768=Meiosis arrest female protein 1, IPR000504=RNA recognition motif domain, IPR025605=OST-HTH/LOTUS domain" CG17018 16-Dec-15 2015_12 ENSMUSG00000060657(4921513D23Rik) viable FBgn0028941 CG16853 http://flybase.net/reports/FBgn0028941.html protein_coding_gene BG:BACR48E02.3 CG16853 16-Dec-15 2015_12 viable FBgn0266705 CR45195 http://flybase.net/reports/FBgn0266705.html non_protein_coding_gene CR45195 16-Dec-15 2015_12 FBgn0050398 CG30398 http://flybase.net/reports/FBgn0050398.html protein_coding_gene IPR007330=MIT CG30398 16-Dec-15 2015_12 ENSDARG00000044766(mitd1) WBGene00013436(Y66D12A.10) ENSXETG00000019386(TEgg072n07.1) ENSMUSG00000026088(Mitd1) ENSG00000158411(MITD1) viable FBgn0065360 l(2)SH1749 lethal (2) SH1749 http://flybase.net/reports/FBgn0065360.html gene l(2)SH2 1749 16-Dec-15 2015_12 "lethal,recessive" FBgn0031015 CG14197 http://flybase.net/reports/FBgn0031015.html protein_coding_gene 16-Dec-15 2015_12 FBgn0004543 l(4)102CDn lethal (4) 102CDn http://flybase.net/reports/FBgn0004543.html gene "l(4)CDn, l(4)28" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0036662 CG9706 http://flybase.net/reports/FBgn0036662.html protein_coding_gene 0008521=acetyl-CoA transporter activity 0016021=integral component of membrane "IPR024371=Acetyl-coenzyme A transporter 1, IPR020846=Major facilitator superfamily domain" CG9706 16-Dec-15 2015_12 ENSDARG00000020085(slc33a1) YBR220C() WBGene00012033(T26C5.3) ENSXETG00000012306(SLC33A1) ENSMUSG00000027822(Slc33a1) ENSG00000169359(SLC33A1) "partially lethal - majority die,some die during pupal stage" FBgn0028596 l(2)k07521 lethal (2) k07521 http://flybase.net/reports/FBgn0028596.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035663 CG6462 http://flybase.net/reports/FBgn0035663.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP127 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG6462 16-Dec-15 2015_12 viable FBgn0263526 mir-4971 mir-4971 stem loop http://flybase.net/reports/FBgn0263526.html miRNA_gene "CR43511, dme-mir-4971" CR43511 16-Dec-15 2015_12 FBgn0002902 mus305 mutagen-sensitive 305 http://flybase.net/reports/FBgn0002902.html gene mus(3)305 16-Dec-15 2015_12 "viable,chemical sensitive,recessive,radiation sensitive" FBgn0013392 anon-1Bc anon-1Bc http://flybase.net/reports/FBgn0013392.html gene T9 16-Dec-15 2015_12 " embryonic stage , pupal stage " FBgn0001738 l(1)HM8 lethal (1) HM8 http://flybase.net/reports/FBgn0001738.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,visible,female fertile" wing FBgn0024702 bcd::RpLP2 bcd::RpLP2 http://flybase.net/reports/FBgn0024702.html engineered_fusion_gene bcd::RpP1 16-Dec-15 2015_12 FBgn0066329 rigel rigel http://flybase.net/reports/FBgn0066329.html gene rig 16-Dec-15 2015_12 FBgn0022037 l(2)k08504 lethal (2) k08504 http://flybase.net/reports/FBgn0022037.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041600 gav gav http://flybase.net/reports/FBgn0041600.html gene 16-Dec-15 2015_12 FBgn0034688 CG11474 http://flybase.net/reports/FBgn0034688.html protein_coding_gene IPR002791=Domain of unknown function DUF89 CG11474 16-Dec-15 2015_12 ENSDARG00000055676(zgc:110816) YMR027W() WBGene00009290(F31D4.2) ENSXETG00000008483(BC075279.1) ENSMUSG00000061759(1700052N19Rik) ENSG00000146476(C6orf211) viable FBgn0037576 Or85a Odorant receptor 85a http://flybase.net/reports/FBgn0037576.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0046331=lateral inhibition" "0032590=dendrite membrane, 0016021=integral component of membrane" "CG7454, 85a, DOR31, DmOR85A, or85a, 85A.4" "IPR004117=Olfactory receptor, Drosophila" CG7454 16-Dec-15 2015_12 "viable,visible" chaeta FBgn0044396 Scim32 Sensitized chromosome inheritance modifier 32 http://flybase.net/reports/FBgn0044396.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0027154 l(3)3a lethal (3) 3a http://flybase.net/reports/FBgn0027154.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0265796 CR44585 http://flybase.net/reports/FBgn0265796.html non_protein_coding_gene CR44585 16-Dec-15 2015_12 FBgn0036482 CG13457 http://flybase.net/reports/FBgn0036482.html "FBgn0063729, FBgn0065009" protein_coding_gene "BcDNA:AT16542, BcDNA:AT15860" CG13457 16-Dec-15 2015_12 viable FBgn0051797 CG31797 http://flybase.net/reports/FBgn0051797.html "FBgn0032766, FBgn0032767" protein_coding_gene "CG15176, CT35089, CG15175" CG31797 16-Dec-15 2015_12 FBgn0083037 snoRNA:ë¬18S-525b snoRNA:ë¬18S-525b http://flybase.net/reports/FBgn0083037.html snoRNA_gene "CR34572, psi18S-525b" CR34572 16-Dec-15 2015_12 FBgn0033079 Fmo-2 Flavin-containing monooxygenase 2 http://flybase.net/reports/FBgn0033079.html protein_coding_gene "0050661=NADP binding, 0004497=monooxygenase activity, 0004499=N,N-dimethylaniline monooxygenase activity, 0050660=flavin adenine dinucleotide binding" 0055114=oxidation-reduction process "0005829=cytosol, 0005739=mitochondrion, 0043231=intracellular membrane-bounded organelle" "flavin-containing monooxygenase 2, DmFMO-2, CG3174, fmo2" "IPR016040=NAD(P)-binding domain, IPR000960=Flavin monooxygenase FMO, IPR020946=Flavin monooxygenase-like" CG3174 16-Dec-15 2015_12 "ENSDARG00000039211(zgc:77439),ENSDARG00000069158,ENSDARG00000069333(LOC793236)" YHR176W(FMO1) "WBGene00007254(C01H6.4),WBGene00016728(C46H11.2)" ENSXETG00000009098() "ENSMUSG00000051081(Gm4847),ENSMUSG00000026691(Fmo3),ENSMUSG00000026560(Fmo9),ENSMUSG00000040170(Fmo2),ENSMUSG00000040181(Fmo1),ENSMUSG00000028088(Fmo5),ENSMUSG00000026692(Fmo4)" "ENSG00000117507,ENSG00000007933(FMO3),ENSG00000010932(FMO1),ENSG00000094963(FMO2),ENSG00000076258(FMO4),ENSG00000131781(FMO5)" viable FBgn0040608 CG14246 http://flybase.net/reports/FBgn0040608.html "FBgn0052950, FBtr0085041, FBpp0084413, FBtr0085042, FBpp0084414" protein_coding_gene CG32950 CG14246 16-Dec-15 2015_12 FBgn0014285 l(3)64Ad lethal (3) 64Ad http://flybase.net/reports/FBgn0014285.html gene 16-Dec-15 2015_12 FBgn0016725 Roa Rough anteriorly http://flybase.net/reports/FBgn0016725.html gene 0042051=compound eye photoreceptor development 16-Dec-15 2015_12 "lethal,recessive" "ommatidium,interommatidial bristle,pigment cell" FBgn0063899 Rst(2)At Resistance to Asobara tabida http://flybase.net/reports/FBgn0063899.html gene Rat 16-Dec-15 2015_12 FBgn0259707 CG42361 http://flybase.net/reports/FBgn0259707.html "FBgn0035038, FBan0013588, FBgn0035037, FBan0003579" protein_coding_gene CG3579 IPR009218=Predicted HD phosphohydrolase CG42361 16-Dec-15 2015_12 viable FBgn0262440 mir-280 mir-280 stem loop http://flybase.net/reports/FBgn0262440.html "FBgn0067713, FBgn0262295" miRNA_gene "dme-miR-280, mir-280, CR33591, miR-280, CR43002" CR43002 16-Dec-15 2015_12 viable FBgn0063406 l(3)CG1 lethal (3) CG1 http://flybase.net/reports/FBgn0063406.html gene Complementation Group 1 16-Dec-15 2015_12 "lethal,recessive" FBgn0264993 CR44144 http://flybase.net/reports/FBgn0264993.html non_protein_coding_gene CR44144 16-Dec-15 2015_12 FBgn0031874 CG13775 http://flybase.net/reports/FBgn0031874.html protein_coding_gene "0003677=DNA binding, 0046983=protein dimerization activity" "IPR008906=HAT dimerisation domain, C-terminal, IPR003656=Zinc finger, BED-type, IPR012337=Ribonuclease H-like domain" CG13775 16-Dec-15 2015_12 "ENSDARG00000038872,ENSDARG00000054955,ENSDARG00000067485,ENSDARG00000032304,ENSDARG00000025412,ENSDARG00000068066,ENSDARG00000044926" WBGene00008283(C53D6.6) ENSXETG00000014526(ZBED4) ENSMUSG00000034333(Zbed4) ENSG00000100426(ZBED4) embryonic/larval hemocyte | third instar larval stage FBgn0265829 CR44618 http://flybase.net/reports/FBgn0265829.html non_protein_coding_gene lincRNA.98 CR44618 16-Dec-15 2015_12 FBgn0004224 l(3)84Fl lethal (3) 84Fl http://flybase.net/reports/FBgn0004224.html gene 16-Dec-15 2015_12 lethal FBgn0002644 man mandarin http://flybase.net/reports/FBgn0002644.html gene 16-Dec-15 2015_12 "visible,eye color defective" pigment cell FBgn0046258 CG12880 http://flybase.net/reports/FBgn0046258.html FBgn0039539 protein_coding_gene BEST:LD29228 CG12880 16-Dec-15 2015_12 "viable,visible,planar polarity defective" trichogen cell FBgn0022359 Sodh-2 Sorbitol dehydrogenase-2 http://flybase.net/reports/FBgn0022359.html protein_coding_gene "0008270=zinc ion binding, 0003939=L-iditol 2-dehydrogenase activity" 0055114=oxidation-reduction process "Sorbitol dehydrogenase 2, SODH-2, DM_7299382, Sdh, Sdh-2, CG4649" "IPR002085=Alcohol dehydrogenase superfamily, zinc-type, IPR013154=Alcohol dehydrogenase, N-terminal, IPR011032=GroES-like, IPR013149=Alcohol dehydrogenase, C-terminal, IPR016040=NAD(P)-binding domain, IPR002328=Alcohol dehydrogenase, zinc-type, conserved site" CG4649 16-Dec-15 2015_12 ENSDARG00000053405 "YJR159W(SOR1),YDL246C(SOR2),YLR070C(XYL2)" "WBGene00011004(R04B5.6),WBGene00011003(R04B5.5)" ENSXETG00000023897(sord) ENSMUSG00000027227(Sord) ENSG00000140263(SORD) " larval stage , adult stage , pupal stage " viable FBgn0065479 l(2)SH1295 lethal (2) SH1295 http://flybase.net/reports/FBgn0065479.html gene l(2)SH2 1295 16-Dec-15 2015_12 "lethal,recessive" FBgn0014339 lphB larval photokinesis B http://flybase.net/reports/FBgn0014339.html gene 0009416=response to light stimulus 16-Dec-15 2015_12 visual behavior defective FBgn0025633 CG13366 http://flybase.net/reports/FBgn0025633.html protein_coding_gene "0048734=proboscis morphogenesis, 0035220=wing disc development, 0045214=sarcomere organization, 0007527=adult somatic muscle development, 0048802=notum morphogenesis" "SPECC1L-ortholog, SPECC1L ortholog, AAD55419, split discs, EG:118B3.2" IPR001715=Calponin homology domain CG13366 16-Dec-15 2015_12 "ENSDARG00000006719(cytsaa),ENSDARG00000042232(cytsab),ENSDARG00000029480(si:dkey-13b16.2)" ENSXETG00000016155(SMTN) "ENSMUSG00000033444(Cytsa),ENSMUSG00000042331(Cytsb)" "ENSG00000100014(SPECC1L),ENSG00000128487(SPECC1)" "viable,sterile,flightless,partially lethal - majority die,some die during pharate adult stage" "indirect flight muscle,sarcomereMef2.PR,wing,proboscis,mesothoracic tergum" FBgn0010714 l(3)00281 lethal (3) 00281 http://flybase.net/reports/FBgn0010714.html gene 0045995=regulation of embryonic development 16-Dec-15 2015_12 "lethal,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,dorsal,maternal effect,head" FBgn0011089 l(1)Q49 lethal (1) Q49 http://flybase.net/reports/FBgn0011089.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0002382 l(3)93Cb lethal (3) 93Cb http://flybase.net/reports/FBgn0002382.html gene "l(3)er5, er5" 16-Dec-15 2015_12 "lethal,recessive" FBgn0028347 l(1)G0182 lethal (1) G0182 http://flybase.net/reports/FBgn0028347.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0024293 Spn43Ab Serpin 43Ab http://flybase.net/reports/FBgn0024293.html "FBgn0033146, FBgn0063808" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "Serine protease inhibitor 43Ab, spn43Ab, CG1865, SER2, Serine protease inhibitor 2, Ser2, anon-WO0118057.2" "IPR000215=Serpin family, IPR023796=Serpin domain, IPR023795=Serpin, conserved site" CG1865 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0261952 srw shrew http://flybase.net/reports/FBgn0261952.html "FBgn0003508, FBgn0035525" protein_coding_gene "0090098=positive regulation of decapentaplegic signaling pathway, 0010629=negative regulation of gene expression, 0007378=amnioserosa formation, 0009953=dorsal/ventral pattern formation" "CG11582, shrew" IPR006761=Twisted gastrulation (Tsg) protein CG11582 16-Dec-15 2015_12 FBgn0003230 ref(2)M refractory to sigma M http://flybase.net/reports/FBgn0003230.html gene Ref(2)Me 16-Dec-15 2015_12 FBgn0016122 Acer Angiotensin-converting enzyme-related http://flybase.net/reports/FBgn0016122.html FBgn0022076 protein_coding_gene "0004222=metalloendopeptidase activity, 0008241=peptidyl-dipeptidase activity, 0008270=zinc ion binding" "0007507=heart development, 0003007=heart morphogenesis, 0002027=regulation of heart rate, 0006508=proteolysis, 0045938=positive regulation of circadian sleep/wake cycle, sleep, 0030431=sleep" "0005576=extracellular region, 0016020=membrane, 0005615=extracellular space" "ACER, ACE, acer, l(2)k07704, CG10593, angiotensin-converting enzyme-related" "IPR001548=Peptidase M2, peptidyl-dipeptidase A" CG10593 16-Dec-15 2015_12 ENSDARG00000016918(ace2) WBGene00000039(acn-1) ENSMUSG00000015405(Ace2) ENSG00000130234(ACE2) " embryonic stage | stage 14-15 , embryonic stage&&larval stage&&adult stage " embryonic/larval dorsal vessel

"viable,fertile,circadian behavior defective,sleep defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,short lived" "heart primordium,adult heart chamber" FBgn0002132 l(2)K207 lethal (2) K207 http://flybase.net/reports/FBgn0002132.html gene 16-Dec-15 2015_12 lethal FBgn0019694 l(3)68Fg lethal (3) 68Fg http://flybase.net/reports/FBgn0019694.html gene l(3)68Fa 16-Dec-15 2015_12 lethal FBgn0027841 CstF-64 Cleavage stimulation factor 64 kilodalton subunit http://flybase.net/reports/FBgn0027841.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0006379=mRNA cleavage, 0022008=neurogenesis" 0005848=mRNA cleavage stimulating factor complex "CStF 64, cleavage stimulation factor, dCstF64, CstF 64, CG7697, CstF64" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR025742=Cleavage stimulation factor subunit 2, hinge domain, IPR000504=RNA recognition motif domain, IPR026896=Transcription termination and cleavage factor, C-terminal domain" CG7697 16-Dec-15 2015_12 ENSDARG00000044009(cstf2) YGL044C(RNA15) WBGene00000774(cpf-2) ENSXETG00000009642() "ENSMUSG00000031256(Cstf2),ENSMUSG00000053536(Cstf2t)" "ENSG00000101811(CSTF2),ENSG00000177613(CSTF2T)" embryonic stage -- adult stage "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC29486 K 0.038131594 1.094356806 -0.813179488 1.081138392 1.885097034 0.557258589 FBgn0050069 CG30069 http://flybase.net/reports/FBgn0050069.html "FBgn0033909, FBgn0033910" protein_coding_gene "CG8381, CG13017" CG30069 16-Dec-15 2015_12 "lethal,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" wing FBgn0023127 anon-10Abb anon-10Abb http://flybase.net/reports/FBgn0023127.html gene 21 16-Dec-15 2015_12 FBgn0026607 Act57B::Act88F Act57B::Act88F http://flybase.net/reports/FBgn0026607.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0267110 CR45550 http://flybase.net/reports/FBgn0267110.html non_protein_coding_gene CR45550 16-Dec-15 2015_12 FBgn0259717 CG42371 http://flybase.net/reports/FBgn0259717.html protein_coding_gene CG42371 16-Dec-15 2015_12 ENSMUSG00000062691 ENSG00000218739 FBgn0083251 E(smoDN)M Enhancer of smoDN group M http://flybase.net/reports/FBgn0083251.html gene 0007224=smoothened signaling pathway Group M 16-Dec-15 2015_12 "cell lethalcell lethal,somatic clone,lethal,recessive" FBgn0033092 CG9422 http://flybase.net/reports/FBgn0033092.html FBgn0063682 protein_coding_gene 0003676=nucleic acid binding "0009267=cellular response to starvation, 0022008=neurogenesis" BcDNA:RE35072 IPR002775=DNA/RNA-binding protein Alba-like CG9422 16-Dec-15 2015_12 ENSDARG00000070131(zgc:92794) "ENSXETG00000011501(C9orf23),ENSXETG00000025487(RPP25)" "ENSMUSG00000036114(2810432D09Rik),ENSMUSG00000062309(Rpp25)" "ENSG00000164967(C9orf23),ENSG00000178718(RPP25)" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0016781 anon-8Da anon-8Da http://flybase.net/reports/FBgn0016781.html gene 16-Dec-15 2015_12 FBgn0002767 mit(1)18 mitotic 18 http://flybase.net/reports/FBgn0002767.html gene 16-Dec-15 2015_12 FBgn0003216 rde reduced eye http://flybase.net/reports/FBgn0003216.html gene "0007629=flight behavior, 0001745=compound eye morphogenesis" 16-Dec-15 2015_12 flight defective "eye,maxillary palpus" FBgn0005275 Les Lesbian http://flybase.net/reports/FBgn0005275.html gene 16-Dec-15 2015_12 "courtship behavior defective,female" FBgn0003337 Scoop Scoop http://flybase.net/reports/FBgn0003337.html gene "Sc, Scp" 16-Dec-15 2015_12 "visible,viable,fertile,body color defective" "wing,abdomen" FBgn0021783 l(3)95BCb lethal (3) 95BCb http://flybase.net/reports/FBgn0021783.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038660 CG14291 http://flybase.net/reports/FBgn0038660.html protein_coding_gene "0016250=N-sulfoglucosamine sulfohydrolase activity, 0008484=sulfuric ester hydrolase activity" 0008152=metabolic process "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR024607=Sulfatase, conserved site, IPR000917=Sulfatase, IPR017850=Alkaline-phosphatase-like, core domain" CG14291 16-Dec-15 2015_12 ENSDARG00000032087(sgsh) ENSXETG00000019651(SGSH) ENSMUSG00000005043(Sgsh) ENSG00000181523(SGSH) viable FBgn0004557 Su(var)208 Suppressor of variegation 208 http://flybase.net/reports/FBgn0004557.html gene 208 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0261266 zuc zucchini http://flybase.net/reports/FBgn0261266.html "FBgn0004056, FBgn0032389" protein_coding_gene "0016891=endoribonuclease activity, producing 5'-phosphomonoesters" "0030717=karyosome formation, 0046843=dorsal appendage formation, 0048477=oogenesis, 0034587=piRNA metabolic process, 0031047=gene silencing by RNA" "0043186=P granule, 0005739=mitochondrion" "Zucchini, CG12314, Zuc, ZUC" IPR025202=Phospholipase D-like domain CG12314 16-Dec-15 2015_12 ENSDARG00000059951(zgc:162591) ENSXETG00000005747(TGas067k05.1) ENSMUSG00000043648(Pld6) ENSG00000179598(PLD6) FBgn0046875 Obp83g Odorant-binding protein 83g http://flybase.net/reports/FBgn0046875.html "FBgn0037401, FBgn0051558, FBgn0063042" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "83g, CG31558, CG15583, DmelObp83g, Obp83f, BcDNA:RE27306, obp83g" IPR006170=Pheromone/general odorant binding protein CG31558 16-Dec-15 2015_12 FBgn0039007 CCAP Crustacean cardioactive peptide http://flybase.net/reports/FBgn0039007.html protein_coding_gene "0071855=neuropeptide receptor binding, 0005184=neuropeptide hormone activity" "0008016=regulation of heart contraction, 0007218=neuropeptide signaling pathway, 0045823=positive regulation of heart contraction, 0010460=positive regulation of heart rate" "0005615=extracellular space, 0005576=extracellular region" "crustacean cardioactive peptide, CCAP prepropeptide, Ccap, CG4910, Crustacean Cardioactive Peptide, Cardioacceleratory peptide, DmCCAP, CCAP, ccap, Crustacean cardioactive peptide" IPR024276=Crustacean cardioactive peptide CG4910 16-Dec-15 2015_12 "viable,fertile,eclosion rhythm defective" FBgn0261647 Axud1 http://flybase.net/reports/FBgn0261647.html "FBgn0028485, FBgn0259279" protein_coding_gene 0043565=sequence-specific DNA binding "0008285=negative regulation of cell proliferation, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG4272, DAxud1, BcDNA:GH09817, C676" IPR023260=Cysteine/serine-rich nuclear protein family CG4272 16-Dec-15 2015_12 "ENSDARG00000038429(csrnp1b),ENSDARG00000031426(csrnp1a)" WBGene00016562(C41D11.3) "ENSXETG00000020836(CSRNP3),ENSXETG00000009634(CSRNP2),ENSXETG00000004234(CSRNP1)" "ENSG00000144655(CSRNP1),ENSG00000178662(CSRNP3)" FBgn0052226 Pex23 Peroxin 23 http://flybase.net/reports/FBgn0052226.html "FBgn0036965, FBgn0036966" protein_coding_gene 0030246=carbohydrate binding 0016021=integral component of membrane "DmelPex23, CG32226, CG18565, CG6468" "IPR006614=Peroxin/Ferlin domain, IPR001079=Galectin, carbohydrate recognition domain, IPR006624=Beta-propeller repeat TECPR, IPR010482=Peroxin domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG32226 16-Dec-15 2015_12 WBGene00011348(T01H3.2) ENSXETG00000024038(TECPR1) ENSMUSG00000066621(Tecpr1) ENSG00000205356(TECPR1) viable FBgn0030485 CG1998 http://flybase.net/reports/FBgn0030485.html protein_coding_gene "0000254=C-4 methylsterol oxidase activity, 0005506=iron ion binding" "0006633=fatty acid biosynthetic process, 0055114=oxidation-reduction process" IPR006694=Fatty acid hydroxylase CG1998 16-Dec-15 2015_12 ENSDARG00000023820(zgc:55420) YGR060W(ERG25) "WBGene00009902(F49E12.9),WBGene00009903(F49E12.10)" ENSXETG00000008410(C5orf4) ENSMUSG00000031604(Sc4mol) ENSG00000170271(C5orf4) "viable,visible" trichogen cell FBgn0266710 hog hog http://flybase.net/reports/FBgn0266710.html "FBgn0266546, FBgn0052595" protein_coding_gene CG32595 "IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG32595 16-Dec-15 2015_12 FBgn0266026 CR44791 http://flybase.net/reports/FBgn0266026.html non_protein_coding_gene CR44791 16-Dec-15 2015_12 FBgn0021851 l(2)k14602 lethal (2) k14602 http://flybase.net/reports/FBgn0021851.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050095 CG30095 http://flybase.net/reports/FBgn0050095.html FBgn0034077 protein_coding_gene CG8425 CG30095 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0040244 anon-57Bd anon-57Bd http://flybase.net/reports/FBgn0040244.html gene 16-Dec-15 2015_12 FBgn0001925 l(2)25Cf lethal (2) 25Cf http://flybase.net/reports/FBgn0001925.html gene "jf20, l(2)jf20" 16-Dec-15 2015_12 lethal FBgn0024500 Acp53Eb Accessory gland protein 53Eb http://flybase.net/reports/FBgn0024500.html gene 0007321=sperm displacement 16-Dec-15 2015_12 FBgn0058359 CG40359 http://flybase.net/reports/FBgn0058359.html FBan0040359 protein_coding_gene 16-Dec-15 2015_12 FBgn0027341 Gfat1 Glutamine:fructose-6-phosphate aminotransferase 1 http://flybase.net/reports/FBgn0027341.html "FBgn0058197, FBan0012449" protein_coding_gene "0030246=carbohydrate binding, 0004360=glutamine-fructose-6-phosphate transaminase (isomerizing) activity" "1901137=carbohydrate derivative biosynthetic process, 0005975=carbohydrate metabolic process" "GFAT, gfat1, CG12449, CG40197, Dmel/Gfat1, gfat, Gfat" "IPR001347=Sugar isomerase (SIS), IPR017932=Glutamine amidotransferase type 2 domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR005855=Glucosamine-fructose-6-phosphate aminotransferase, isomerising" CG12449 16-Dec-15 2015_12 ENSDARG00000044094(gfpt2) YKL104C(GFA1) "WBGene00008546(F07A11.2),WBGene00009035(F22B3.4)" ENSXETG00000008199(GFPT1) "ENSMUSG00000020363(Gfpt2),ENSMUSG00000029992(Gfpt1)" "ENSG00000131459(GFPT2),ENSG00000198380(GFPT1)" lethal FBgn0260959 MCPH1 Microcephalin http://flybase.net/reports/FBgn0260959.html "FBgn0260792, FBgn0033664, FBgn0033666, FBgn0050038, FBtr0088057, FBpp0087163, FBgn0086755" protein_coding_gene "0016319=mushroom body development, 0007279=pole cell formation, 0045448=mitotic cell cycle, embryonic, 0007067=mitotic nuclear division" 0005634=nucleus "CG8981, CG13184, mcph1, microcephalin, awol, Dmcph1, CG42572, absent without leave, CG30038" "IPR022047=Microcephalin-like, IPR001357=BRCT domain" CG42572 16-Dec-15 2015_12 DRSC28302 K -0.268755354 0.143628475 -0.369184272 0.395835503 -1.749423958 0.281462988 FBgn0015765 p38a p38a MAP kinase http://flybase.net/reports/FBgn0015765.html "FBgn0013952, FBgn0022991" protein_coding_gene "0016909=SAP kinase activity, 0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004707=MAP kinase activity" "0050832=defense response to fungus, 0042542=response to hydrogen peroxide, 0003007=heart morphogenesis, 0002385=mucosal immune response, 0045793=positive regulation of cell size, 0006952=defense response, 0038001=paracrine signaling, 0006979=response to oxidative stress, 0071276=cellular response to cadmium ion, 0072593=reactive oxygen species metabolic process, 0007165=signal transduction, 0042742=defense response to bacterium, 0008348=negative regulation of antimicrobial humoral response, 0042594=response to starvation, 0034614=cellular response to reactive oxygen species, 0006970=response to osmotic stress, 0071243=cellular response to arsenic-containing substance, 0009408=response to heat, 1900407=regulation of cellular response to oxidative stress, 0006955=immune response, 0000165=MAPK cascade, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0008340=determination of adult lifespan, 0006468=protein phosphorylation" 0005634=nucleus "p38A, p38, CG5475, Dp38, Dmp38a, p38Ka, p38 mitogen-activated protein kinase, D-MPK2, p38alpha, Erk2, p38a MAP kinase, Dp38a, Mpk2, mpk2, stress-activated kinase P38, D-P38a, dp38a, group 2, p38 alpha, DmMPK2, ERK2, p38a, P38, MAPK2, D-p38 MAPK, D-p38a, p38 MAP kinase, dp38, D-p38, dMPK2, Erk-kinase-like, DMPK2" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008352=Mitogen-activated protein (MAP) kinase, p38, IPR017441=Protein kinase, ATP binding site" CG5475 16-Dec-15 2015_12 "ENSDARG00000028721(mapk14b),ENSDARG00000045836(zgc:86905)" YLR113W(HOG1) WBGene00004055(pmk-1) ENSXETG00000022254(MAPK11) "ENSMUSG00000053436(Mapk14),ENSMUSG00000053137(Mapk11)" "ENSG00000112062(MAPK14),ENSG00000185386(MAPK11)" " embryonic stage | late , embryonic stage | early " embryonic/larval hindgut

"viable,reduced,fertile,stress response defective,recessive,starvation stress response defective,heat stress response defective,non-enhancer of variegation,non-suppressor of variegation,short lived,oxidative stress response defective,partially lethal - majority die,nutrition conditional,osmotic stress response defective,immune response defective" FBgn0267331 l(1)1Bb lethal (1) 1Bb http://flybase.net/reports/FBgn0267331.html FBgn0001337 gene "lethal(1)1Bb, EC4, l(1)G4, l(1)C84, l(1)EC4" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0262892 CR43247 http://flybase.net/reports/FBgn0262892.html non_protein_coding_gene "lincRNA.566, CG43247" CR43247 16-Dec-15 2015_12 FBgn0065837 l(2)SH0335 lethal (2) SH0335 http://flybase.net/reports/FBgn0065837.html gene l(2)SH2 0335 16-Dec-15 2015_12 "lethal,recessive" FBgn0040362 CG11379 http://flybase.net/reports/FBgn0040362.html FBgn0029563 protein_coding_gene "bs31h12.y1, EG:BACR42I17.4" CG11379 16-Dec-15 2015_12 viable FBgn0032406 CG14947 http://flybase.net/reports/FBgn0032406.html protein_coding_gene CG14947 16-Dec-15 2015_12 viable FBgn0026702 l(1)G0045 lethal (1) G0045 http://flybase.net/reports/FBgn0026702.html "FBgn0027222, FBgn0027523, FBgn0052763" protein_coding_gene 0004526=ribonuclease P activity 0001682=tRNA 5'-leader removal "CG4129, CG32763, BcDNA:LD21623, l(1)G0312" "IPR012590=POPLD, IPR009723=Ribonuclease P/MRP, subunit POP1" CG32763 16-Dec-15 2015_12 YNL221C(POP1) WBGene00015486(C05D11.9) ENSMUSG00000022325(Pop1) ENSG00000104356(POP1) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,male sterile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17739 E -0.527536317 -0.900057836 0.119432033 1.61636595 -0.341868931 -0.496413408 FBgn0263235 Phae2 Phaedra 2 http://flybase.net/reports/FBgn0263235.html "FBgn0029135, FBgn0032413" protein_coding_gene "0004222=metalloendopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "CG16997, SP147" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG16997 16-Dec-15 2015_12 FBgn0025752 l(3)93Dk lethal (3) 93Dk http://flybase.net/reports/FBgn0025752.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0051914 tRNA:CR31914 transfer RNA:CR31914 http://flybase.net/reports/FBgn0051914.html "FBgn0011841, FBgn0060258" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033458=GAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2L.trna33-AspGTC, tRNA[Asp-GTC], AE002690.trna23-AspGTC, tRNA[[Asp]], tRNA:D2:25D, CR31914, tRNA:asp2:25D, transfer RNA:asp2:25D, tRNA:D:GTC:AE002690-g" CR31914 16-Dec-15 2015_12 FBgn0001948 l(2)27Cc lethal (2) 27Cc http://flybase.net/reports/FBgn0001948.html gene "Complementation group C, C" 16-Dec-15 2015_12 lethal FBgn0262688 CR43158 http://flybase.net/reports/FBgn0262688.html pseudogene_attribute CR43158 16-Dec-15 2015_12 FBgn0263026 CG43321 http://flybase.net/reports/FBgn0263026.html FBgn0031880 protein_coding_gene CG13776 IPR018782=Uncharacterised protein family UPF0466 CG43321 16-Dec-15 2015_12 FBgn0020377 Sr-CII "Scavenger receptor class C, type II" http://flybase.net/reports/FBgn0020377.html FBgn0033700 protein_coding_gene "0005044=scavenger receptor activity, 0030247=polysaccharide binding" "0006955=immune response, 0006952=defense response" "0016020=membrane, 0005887=integral component of plasma membrane" "SR-CII, CG8856, Scavenger Receptor, CT25430, dSR-CII" "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001212=Somatomedin B domain, IPR000436=Sushi/SCR/CCP domain, IPR000998=MAM domain" CG8856 16-Dec-15 2015_12 "ENSDARG00000068475,ENSDARG00000024017" "ENSXETG00000020534(MEP1B),ENSXETG00000016251(Q5FVY5_XENTR)" "ENSMUSG00000026399(Cd55),ENSMUSG00000026401(Daf2)" FBgn0266562 EP2265 http://flybase.net/reports/FBgn0266562.html gene 16-Dec-15 2015_12 embryonic/larval salivary gland FBgn0036162 CG6140 http://flybase.net/reports/FBgn0036162.html protein_coding_gene 0004333=fumarate hydratase activity "0006106=fumarate metabolic process, 0006099=tricarboxylic acid cycle" "0045239=tricarboxylic acid cycle enzyme complex, 0005739=mitochondrion, 0005737=cytoplasm" "IPR024083=Fumarase/histidase, N-terminal, IPR022761=Fumarate lyase, N-terminal, IPR020557=Fumarate lyase, conserved site, IPR000362=Fumarate lyase family, IPR005677=Fumarate hydratase, class II, IPR008948=L-Aspartase-like, IPR018951=Fumarase C, C-terminal" CG6140 16-Dec-15 2015_12 ENSDARG00000068620 YPL262W(FUM1) ENSXETG00000006529(FH) FBgn0028390 anon-50ABd anon-50ABd http://flybase.net/reports/FBgn0028390.html gene D 16-Dec-15 2015_12 FBgn0065511 l(2)SH1170 lethal (2) SH1170 http://flybase.net/reports/FBgn0065511.html gene l(2)SH2 1170 16-Dec-15 2015_12 "lethal,recessive" FBgn0017626 Eig45Ab Eig45Ab http://flybase.net/reports/FBgn0017626.html gene "Ecdysone-induced gene 45A, Eig45-2" 16-Dec-15 2015_12 FBgn0065866 l(2)SH0265 lethal (2) SH0265 http://flybase.net/reports/FBgn0065866.html gene l(2)SH2 0265 16-Dec-15 2015_12 "lethal,recessive" FBgn0026144 CBP sarcoplasmic calcium-binding protein http://flybase.net/reports/FBgn0026144.html protein_coding_gene 0005509=calcium ion binding 0050829=defense response to Gram-negative bacterium "0005829=cytosol, 0005654=nucleoplasm, 0016529=sarcoplasmic reticulum" "BcDNA.GH12350, dCBP, cbp, sarcoplasmic calcium-binding protein, BcDNA:GH12350, CG1435, Ca2+ - binding protein, calcium binding protein" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG1435 16-Dec-15 2015_12 "viable,lethal,recessive" intersegmental nerve FBgn0050385 CG30385 http://flybase.net/reports/FBgn0050385.html "FBgn0033150, FBgn0065015" protein_coding_gene "BcDNA:AT12446, CG11074" CG30385 16-Dec-15 2015_12 ENSMUSG00000039110(Mycbpap) "partially lethal - majority die,some die during pupal stage" FBgn0046706 Haspin Haspin http://flybase.net/reports/FBgn0046706.html "FBgn0058080, FBgn0063167, FBan0040080" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0072354=histone kinase activity (H3-T3 specific), 0005524=ATP binding" "0035556=intracellular signal transduction, 0006468=protein phosphorylation" 0005634=nucleus "CG40080, BcDNA:LD07633, haspin" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR024604=Domain of unknown function DUF3635" CG40080 16-Dec-15 2015_12 "YBL009W(ALK2),YGL021W(ALK1)" "WBGene00017729(F22H10.5),WBGene00021483(Y40A1A.1),WBGene00007258(C01H6.9),WBGene00021214(Y18H1A.10)" ENSMUSG00000050107(Gsg2) ENSG00000177602(GSG2) FBgn0002264 l(3)69Ac lethal (3) 69Ac http://flybase.net/reports/FBgn0002264.html gene "rsg26, rose-gespleten region interval 26, l(3)rsg26" 16-Dec-15 2015_12 lethal FBgn0266904 CR45364 http://flybase.net/reports/FBgn0266904.html non_protein_coding_gene lincRNA.73 CR45364 16-Dec-15 2015_12 FBgn0266381 CR45023 http://flybase.net/reports/FBgn0266381.html non_protein_coding_gene CR45023 16-Dec-15 2015_12 FBgn0023022 l(3)A215.1M3 lethal (3) A215.1M3 http://flybase.net/reports/FBgn0023022.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083313 E(smoDN)1338 Enhancer of smoDN 1338 http://flybase.net/reports/FBgn0083313.html gene 16-Dec-15 2015_12 FBgn0001840 l(1)ts1126 lethal (1) ts1126 http://flybase.net/reports/FBgn0001840.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,visible,male sterile,body color defective" "abdominal tergite & macrochaeta | conditional ts,wing,heat sensitive,tergite" FBgn0002171 l(2)Sp14 lethal (2) Sp14 http://flybase.net/reports/FBgn0002171.html gene 16-Dec-15 2015_12 lethal FBgn0259401 EP-1013 http://flybase.net/reports/FBgn0259401.html gene 16-Dec-15 2015_12 visible wing vein FBgn0015794 Rab18 Rab18 http://flybase.net/reports/FBgn0015794.html FBgn0029784 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0008360=regulation of cell shape, 0032482=Rab protein signal transduction, 0007155=cell adhesion, 0015031=protein transport, 0016192=vesicle-mediated transport" "0005769=early endosome, 0043025=neuronal cell body, 0031982=vesicle" "DRabRP4, Rab18/RP4, CG3129, DRABR4, DmRab18, Rab18, Rab-RP4, 24639915, Rab-r4, rab18, AAF46057, rab-related protein 4, Rab-related protein 4, O18337" "IPR025662=Sigma-54 interaction domain, ATP-binding site 1, IPR003579=Small GTPase superfamily, Rab type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3129 16-Dec-15 2015_12 "ENSDARG00000035084,ENSDARG00000055291(rab18a)" WBGene00004277(rab-18) ENSXETG00000004556(rab18) ENSMUSG00000073639(Rab18) ENSG00000099246(RAB18) viable FBgn0035957 CG5144 http://flybase.net/reports/FBgn0035957.html protein_coding_gene 0004054=arginine kinase activity "IPR022413=ATP:guanido phosphotransferase, N-terminal, IPR022415=ATP:guanido phosphotransferase active site, IPR000749=ATP:guanido phosphotransferase, IPR022414=ATP:guanido phosphotransferase, catalytic domain, IPR014746=Glutamine synthetase/guanido kinase, catalytic domain" CG5144 16-Dec-15 2015_12 "ENSDARG00000035327(ckma),ENSDARG00000040565(ckmb),ENSDARG00000043257(ckbb),ENSDARG00000069752(ckba),ENSDARG00000039929(ckmt2),ENSDARG00000016598(ckmt1),ENSDARG00000069615(zgc:56085)" "ENSXETG00000019108(ckm),ENSXETG00000023038(ckb),ENSXETG00000027612(ckmt1)" "ENSMUSG00000030399(Ckm),ENSMUSG00000001270(Ckb),ENSMUSG00000000308(Ckmt1),ENSMUSG00000021622(Ckmt2)" "ENSG00000166165(CKB),ENSG00000104879(CKM),ENSG00000168775,ENSG00000166998,ENSG00000131730(CKMT2)" viable DRSC23349 EK -0.537180271 0.344312602 -1.928589298 0.084007894 -0.593226677 -1.584902688 FBgn0032637 CG5050 http://flybase.net/reports/FBgn0032637.html protein_coding_gene CG5050 16-Dec-15 2015_12 viable FBgn0001577 l(1)air4 lethal aberrant immune response 4 http://flybase.net/reports/FBgn0001577.html gene air4 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,embryonic/larval lymph gland,melanotic mass" FBgn0034215 Mtap Methylthioadenosine phosphorylase ortholog http://flybase.net/reports/FBgn0034215.html protein_coding_gene "0004645=phosphorylase activity, 0017061=S-methyl-5-thioadenosine phosphorylase activity" "0009116=nucleoside metabolic process, 0016310=phosphorylation" "CG4802, MTAP" "IPR010044=Methylthioadenosine phosphorylase (MTAP), IPR018099=Purine phosphorylase, family 2, conserved site, IPR001369=PNP/MTAP phosphorylase, IPR000845=Nucleoside phosphorylase domain" CG4802 16-Dec-15 2015_12 ENSDARG00000037261(mtap) YLR017W(MEU1) WBGene00015064(B0228.7) ENSXETG00000005467(Q5HZU2_XENTR) ENSMUSG00000062937(Mtap) ENSG00000099810(MTAP) "lethal,partially lethal - majority die" FBgn0053774 CG33774 http://flybase.net/reports/FBgn0053774.html FBgn0064935 protein_coding_gene 0004579=dolichyl-diphosphooligosaccharide-protein glycotransferase activity 0006487=protein N-linked glycosylation 0008250=oligosaccharyltransferase complex "BcDNA:GM20929, Dm_2R:21419" IPR018943=Oligosaccaryltransferase CG33774 16-Dec-15 2015_12 WBGene00011558(T07A5.5) ENSMUSG00000038803(2310016E02Rik) FBgn0266281 CR44966 http://flybase.net/reports/FBgn0266281.html non_protein_coding_gene CR44966 16-Dec-15 2015_12 FBgn0027134 l(3)93Ea lethal (3) 93Ea http://flybase.net/reports/FBgn0027134.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0002662 mat(2)cell-K maternal effect cellularisation defect K http://flybase.net/reports/FBgn0002662.html gene 0007349=cellularization "mat(2)cellRH36, cell-RH36" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage" "stage 5 embryo,maternal effect" FBgn0003005 opht opthalmoptera http://flybase.net/reports/FBgn0003005.html gene ophthalmoptera 16-Dec-15 2015_12 FBgn0037565 CG9626 http://flybase.net/reports/FBgn0037565.html protein_coding_gene Q9VHT6_DROME CG9626 16-Dec-15 2015_12 viable FBgn0029646 CG14423 http://flybase.net/reports/FBgn0029646.html protein_coding_gene CG14423 16-Dec-15 2015_12 viable FBgn0259760 ms(3)Z3-5231 http://flybase.net/reports/FBgn0259760.html gene "0007283=spermatogenesis, 0051276=chromosome organization" "165-104, ms(3)165-104" 16-Dec-15 2015_12 "viable,male sterile" "Y chromosome loop,spermatozoon" FBgn0035921 CG13305 http://flybase.net/reports/FBgn0035921.html FBgn0063034 protein_coding_gene "CT32600, BcDNA:RE33542" CG13305 16-Dec-15 2015_12 viable FBgn0266941 CR45392 http://flybase.net/reports/FBgn0266941.html non_protein_coding_gene lincRNA.596 CR45392 16-Dec-15 2015_12 FBgn0003257 r-l rudimentary-like http://flybase.net/reports/FBgn0003257.html protein_coding_gene "0004588=orotate phosphoribosyltransferase activity, 0004590=orotidine-5'-phosphate decarboxylase activity" "0044205='de novo' UMP biosynthetic process, 0006207='de novo' pyrimidine nucleobase biosynthetic process" 0005875=microtubule associated complex "UMP synthase, orotidine phosphate decarboxylase, Rudimentary-like, UMPS, CG3593, OPRT, ral, OMPDC" "IPR014732=Orotidine 5'-phosphate decarboxylase, IPR029057=Phosphoribosyltransferase-like, IPR004467=Orotate phosphoribosyl transferase domain, IPR018089=Orotidine 5'-phosphate decarboxylase, active site, IPR001754=Orotidine 5'-phosphate decarboxylase domain, IPR013785=Aldolase-type TIM barrel, IPR023031=Orotate phosphoribosyltransferase, IPR011060=Ribulose-phosphate binding barrel, IPR000836=Phosphoribosyltransferase domain" CG3593 16-Dec-15 2015_12 ENSDARG00000012215(umps) YEL021W(URA3) WBGene00011559(umps-1) ENSMUSG00000022814(Umps) ENSG00000114491(UMPS) embryonic stage "viable,fertile" DRSC22784 I 2.177167721 0.736069189 0.739114062 0.34410855 -0.154263108 -0.910030252 FBgn0262985 CG43293 http://flybase.net/reports/FBgn0262985.html protein_coding_gene CG43293 16-Dec-15 2015_12 FBgn0000618 e(y)2 enhancer of yellow 2 http://flybase.net/reports/FBgn0000618.html FBgn0030315 protein_coding_gene "0005515=protein binding, 0070742=C2H2 zinc finger domain binding, 0043035=chromatin insulator sequence binding, 0003713=transcription coactivator activity, 0001094=TFIID-class transcription factor binding, 0003682=chromatin binding" "0031936=negative regulation of chromatin silencing, 0045893=positive regulation of transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0016578=histone deubiquitination, 0016973=poly(A)+ mRNA export from nucleus" "0034399=nuclear periphery, 0071819=DUBm complex, 0005634=nucleus, 0000785=chromatin, 0005643=nuclear pore, 0000124=SAGA complex" "E(y)2, ENY2, Sus1, d, CG15191, e(y)[2]" "IPR018783=Transcription factor, enhancer of yellow 2" CG15191 16-Dec-15 2015_12 ENSDARG00000070046(eny2) YBR111W-A(SUS1) ENSXETG00000027483(ENY2) "ENSMUSG00000022338(Eny2),ENSMUSG00000043295(Gm16373)" ENSG00000120533(ENY2) "visible,recessive,viable,partially lethal - majority die,some die during pupal stage" "wing,eye,macrochaeta,mesothoracic tergum" FBgn0062603 Mod(var)1444 Mod(var)1444 http://flybase.net/reports/FBgn0062603.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1444 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0085711 CG41587 http://flybase.net/reports/FBgn0085711.html FBan0041587 protein_coding_gene 16-Dec-15 2015_12 FBgn0044461 EP3303 EP3303 http://flybase.net/reports/FBgn0044461.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "anterior fascicle & synapse,intersegmental nerve" FBgn0267175 CR45615 http://flybase.net/reports/FBgn0267175.html non_protein_coding_gene CR45615 16-Dec-15 2015_12 FBgn0027279 l(1)G0196 lethal (1) G0196 http://flybase.net/reports/FBgn0027279.html "FBgn0031192, FBgn0052502" protein_coding_gene "0000827=inositol-1,3,4,5,6-pentakisphosphate kinase activity, 0000832=inositol hexakisphosphate 5-kinase activity, 0003993=acid phosphatase activity, 0033857=diphosphoinositol-pentakisphosphate kinase activity" 0006020=inositol metabolic process 0005829=cytosol "CG14616, CG32502" "IPR029033=Histidine phosphatase superfamily, IPR000560=Histidine phosphatase superfamily, clade-2" CG14616 16-Dec-15 2015_12 YLR410W(VIP1) WBGene00018508(F46F11.1) "ENSXETG00000023862(HISPPD1),ENSXETG00000004653(HISPPD2A)" "ENSMUSG00000040648(Ppip5k2),ENSMUSG00000033526(Ppip5k1)" "ENSG00000145725(PPIP5K2),ENSG00000168781(PPIP5K1)" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" DRSC20591 IE 1.305293718 -1.50873131 -0.118072167 -1.641573426 -0.06570399 0.247059908 FBgn0021900 l(2)k12502b lethal (2) k12502b http://flybase.net/reports/FBgn0021900.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032625 CG15136 http://flybase.net/reports/FBgn0032625.html protein_coding_gene "IPR009818=Ataxin-2, C-terminal" CG15136 16-Dec-15 2015_12 viable FBgn0065682 l(2)SH0662 lethal (2) SH0662 http://flybase.net/reports/FBgn0065682.html gene l(2)SH2 0662 16-Dec-15 2015_12 "lethal,recessive" FBgn0032680 Ntf-2r Nuclear transport factor-2-related http://flybase.net/reports/FBgn0032680.html protein_coding_gene 0006606=protein import into nucleus 0005622=intracellular "Dntf-2, CG10174, Dntf-2r, Drosophila nuclear transport factor-2-related, Dntf-2R" "IPR002075=Nuclear transport factor 2, IPR018222=Nuclear transport factor 2, eukaryote" CG10174 16-Dec-15 2015_12 "ENSDARG00000056531(zgc:101555),ENSDARG00000014499(nutf2)" YER009W(NTF2) WBGene00004305(ran-4) ENSXETG00000026897(nutf2) ENSMUSG00000008450(Nutf2) ENSG00000102898(NUTF2) adult stage | male testis

"viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage FBgn0011704 RnrS Ribonucleoside diphosphate reductase small subunit http://flybase.net/reports/FBgn0011704.html FBgn0062214 protein_coding_gene "0004748=ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor" "0006260=DNA replication, 0022008=neurogenesis, 0009186=deoxyribonucleoside diphosphate metabolic process, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0055114=oxidation-reduction process" 0005971=ribonucleoside-diphosphate reductase complex "Rnr2, dRNR2, DmRNR2, RNrS, CG8975, Ribonucleotide reductase, RNRS, Rnrs, anon-WO0118547.148, rnr2, ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit, RNR2" "IPR030475=Ribonucleotide reductase small subunit, acitve site, IPR012348=Ribonucleotide reductase-related, IPR000358=Ribonucleotide reductase small subunit, IPR009078=Ferritin-like superfamily" CG8975 16-Dec-15 2015_12 ENSDARG00000020711(LOC100330864) YJL026W(RNR2) WBGene00004392(rnr-2) "ENSXETG00000003527(rrm2),ENSXETG00000004121(RRM2B)" ENSMUSG00000020649(Rrm2) ENSG00000171848(RRM2) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC07533 IEK -0.461226461 -3.13410515 -0.594178831 -2.859487957 2.544209042 2.992067892 FBgn0011896 tRNA:K2:50C transfer RNA:lys2:50C http://flybase.net/reports/FBgn0011896.html "FBgn0011886, FBgn0050242, FBgn0050507, FBgn0060179" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033444=AAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:lys2:50C, tRNA:K:CTT:AE002787-a, tRNAlys, CR30242, tRNA[Lys][[2]], chr2R.trna75-LysCTT, AE002787.trna16-LysCTT, tRNA:K2, CR30507" CR30507 16-Dec-15 2015_12 FBgn0005027 dw-sc dwarf with scute http://flybase.net/reports/FBgn0005027.html gene 16-Dec-15 2015_12 "visible,viable,reduced" "adult abdomen,adult thorax" FBgn0260745 mfas midline fasciclin http://flybase.net/reports/FBgn0260745.html "FBgn0024211, FBgn0025940, FBgn0043833, FBgn0044703, FBgn0015348" protein_coding_gene 0050839=cell adhesion molecule binding "0007409=axonogenesis, 0032504=multicellular organism reproduction, 0035207=negative regulation of hemocyte proliferation" "0005615=extracellular space, 0005886=plasma membrane" "anon-EST:Liang-97, anon-WO0140519.174, gh06752, CG3359, Midline Fasciclin, 87A7-9/7, clone 97, Mfas, anon-87Af, Midline fasciclin, BEST:GH06752" "IPR000782=FAS1 domain, IPR011489=EMI domain" CG3359 16-Dec-15 2015_12 "ENSDARG00000071586(tgfbi),ENSDARG00000061219(postn),ENSDARG00000043806(sb:cb925)" "ENSXETG00000015068(TGFBI),ENSXETG00000001812(POSTN)" "ENSMUSG00000035493(Tgfbi),ENSMUSG00000027750(Postn)" "ENSG00000120708(TGFBI),ENSG00000133110(POSTN)" FBgn0085715 CG41595 http://flybase.net/reports/FBgn0085715.html FBan0041595 protein_coding_gene 16-Dec-15 2015_12 FBgn0032004 CG8292 http://flybase.net/reports/FBgn0032004.html protein_coding_gene CG8292 16-Dec-15 2015_12 viable FBgn0061165 l(1)3As lethal (1) 3As http://flybase.net/reports/FBgn0061165.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051575 tRNA:CR31575 transfer RNA:CR31575 http://flybase.net/reports/FBgn0051575.html FBgn0060282 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA-ala, AE002708.trna43-AlaAGC, CR31575, tRNA:A:AGC:AE002708-g, tRNA[[Ala]], chr3R.trna49-AlaAGC" CR31575 16-Dec-15 2015_12 FBgn0011854 tRNA:E4:62Ad transfer RNA:glu4:62Ad http://flybase.net/reports/FBgn0011854.html "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052323, FBgn0060246" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033460=GAG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:E4, tRNA:glu4:62Ad, tRNA:E:CTC:AE002584-h, AE002584.trna10-GluCTC, tRNA:Glu, chr3L.trna10-GluCTC, CR32323" CR32323 16-Dec-15 2015_12 FBgn0014402 vah ventral abdominal hole http://flybase.net/reports/FBgn0014402.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "central nervous system,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt" FBgn0003418 sla slimma http://flybase.net/reports/FBgn0003418.html gene 16-Dec-15 2015_12 "visible,recessive,male fertile,viable,male,female,reduced,female sterile" "adult abdomen,wing" FBgn0031304 CG4552 http://flybase.net/reports/FBgn0031304.html protein_coding_gene 0005096=GTPase activator activity "0007298=border follicle cell migration, 0006909=phagocytosis, 0043087=regulation of GTPase activity" "IPR001763=Rhodanese-like domain, IPR000195=Rab-GTPase-TBC domain" CG4552 16-Dec-15 2015_12 ENSDARG00000044357(tbc1d23) WBGene00008974(tbc-1) ENSXETG00000011861(TBC1D23) ENSMUSG00000022749(Tbc1d23) ENSG00000036054(TBC1D23) "cell migration defective,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "border follicle cell,mesothoracic tergum" FBgn0011702 Res Resurrector http://flybase.net/reports/FBgn0011702.html gene Res1 16-Dec-15 2015_12 mitotic cell cycle defective "embryonic abdomen,cleavage nucleus" FBgn0266723 Trs31 TRAPP subunit 31 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266723.html "FBgn0044805, FBgn0033962" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0006888=ER to Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport" 0030008=TRAPP complex "Trs31, CG10153, Trs31p" "IPR007194=Transport protein particle (TRAPP) component, IPR016696=TRAPP I complex, subunit 5, IPR024096=NO signalling/Golgi transport ligand-binding domain" CG10153 16-Dec-15 2015_12 ENSDARG00000026068(trappc5) WBGene00013259(Y57A10A.16) ENSXETG00000001289(trappc5) ENSMUSG00000040236(Trappc5) ENSG00000181029(TRAPPC5) FBgn0029153 Menl-2 Malic enzyme like-2 http://flybase.net/reports/FBgn0029153.html "FBgn0034123, FBgn0050097, FBtr0087161, FBpp0086305, FBtr0087162, FBpp0086306, FBtr0087163, FBpp0086307, FBtr0087164, FBpp0086308, FBtr0087165, FBpp0086309, FBtr0087166, FBpp0086310" protein_coding_gene "0051287=NAD binding, 0046554=malate dehydrogenase (NADP+) activity, 0004473=malate dehydrogenase (decarboxylating) (NADP+) activity, 0004471=malate dehydrogenase (decarboxylating) (NAD+) activity" "0006108=malate metabolic process, 0055114=oxidation-reduction process" "Menl-2, CG7969, CG30097" "IPR016040=NAD(P)-binding domain, IPR001891=Malic oxidoreductase, IPR012302=Malic enzyme, NAD-binding, IPR012301=Malic enzyme, N-terminal domain" CG7969 16-Dec-15 2015_12 YKL029C(MAE1) FBgn0266102 CR44839 http://flybase.net/reports/FBgn0266102.html pseudogene_attribute CR44839 16-Dec-15 2015_12 FBgn0085423 CG34394 http://flybase.net/reports/FBgn0085423.html "FBgn0040712, FBgn0031527, FBgn0064872" protein_coding_gene "CG3304, BcDNA:RE58243, CG15411" IPR004182=GRAM domain CG34394 16-Dec-15 2015_12 "YLR072W(),YFL042C(),YDR326C(YSP2)" ENSXETG00000001240(GRAMD1B) "ENSMUSG00000040111(Gramd1b),ENSMUSG00000001248(Gramd1a)" "ENSG00000023171(GRAMD1B),ENSG00000089351(GRAMD1A),ENSG00000178075(GRAMD1C)" "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053341 CG33341 http://flybase.net/reports/FBgn0053341.html protein_coding_gene unnamed IPR006631=Protein of unknown function DM4/12 CG33341 16-Dec-15 2015_12 FBgn0085475 CG34446 http://flybase.net/reports/FBgn0085475.html "FBgn0050219, FBgn0034754, FBan0030219" protein_coding_gene "CG13513, CG30219" CG34446 16-Dec-15 2015_12 FBgn0001712 l(1)ESHS33 lethal (1) ESHS33 http://flybase.net/reports/FBgn0001712.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027521 CG3679 http://flybase.net/reports/FBgn0027521.html protein_coding_gene BcDNA:LD21675 CG3679 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0259389 C107 http://flybase.net/reports/FBgn0259389.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0033556 CG12343 http://flybase.net/reports/FBgn0033556.html protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" Syf2 IPR013260=mRNA splicing factor SYF2 CG12343 16-Dec-15 2015_12 ENSDARG00000004706(syf2) WBGene00019402(K04G7.11) ENSXETG00000022797(cbpin) ENSMUSG00000028821(Syf2) ENSG00000117614(SYF2) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" DRSC06135 E -0.220023632 0.515060148 1.792929796 0.956395364 -0.69217173 0.349297846 FBgn0028065 l(3)S091306 lethal (3) S091306 http://flybase.net/reports/FBgn0028065.html gene 0913/06 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002278 l(3)73Ac lethal (3) 73Ac http://flybase.net/reports/FBgn0002278.html gene l(3)std2 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0039360 CLS Cardiolipin synthase http://flybase.net/reports/FBgn0039360.html protein_coding_gene "0008808=cardiolipin synthase activity, 0017169=CDP-alcohol phosphatidyltransferase activity" "0006754=ATP biosynthetic process, 0007006=mitochondrial membrane organization, 0008654=phospholipid biosynthetic process" "0016020=membrane, 0016021=integral component of membrane" "cardiolipin synthase, CG4774" IPR000462=CDP-alcohol phosphatidyltransferase CG4774 16-Dec-15 2015_12 ENSDARG00000038000(zgc:85909) YDL142C(CRD1) WBGene00017763(crls-1) ENSXETG00000026037(CRLS1) ENSMUSG00000027357(Crls1) ENSG00000088766(CRLS1) viable mitochondrion FBgn0051912 CR31912 http://flybase.net/reports/FBgn0051912.html non_protein_coding_gene CG31912 CR31912 16-Dec-15 2015_12 FBgn0004208 l(3)84Ef lethal (3) 84Ef http://flybase.net/reports/FBgn0004208.html gene 16-Dec-15 2015_12 lethal FBgn0038868 CG5862 http://flybase.net/reports/FBgn0038868.html protein_coding_gene IPR019153=DDRGK domain containing protein CG5862 16-Dec-15 2015_12 WBGene00022865(ZK1236.7) ENSXETG00000021528(DDRGK1) ENSMUSG00000068290(Ddrgk1) ENSG00000198171(DDRGK1) "visible,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0052649 CG32649 http://flybase.net/reports/FBgn0052649.html FBgn0030430 protein_coding_gene 0004672=protein kinase activity "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" 0005739=mitochondrion CG4410 "IPR011009=Protein kinase-like domain, IPR004147=UbiB domain" CG32649 16-Dec-15 2015_12 "ENSDARG00000011955(LOC799071),ENSDARG00000020123(zgc:92578),ENSDARG00000032426(wu:fi03c06)" YGL119W(ABC1) WBGene00000767(coq-8) ENSXETG00000002574(ADCK4) "ENSMUSG00000026489(Cabc1),ENSMUSG00000003762(Adck4)" "ENSG00000123815(ADCK4),ENSG00000163050(ADCK3)" viable FBgn0000595 Etd Eye tissue determiner http://flybase.net/reports/FBgn0000595.html gene 16-Dec-15 2015_12 visible "eye,ventral" FBgn0034736 CG6018 http://flybase.net/reports/FBgn0034736.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "DmalphaE1-O, orphan alpha-esterase, alphaE1-O" "IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG6018 16-Dec-15 2015_12 "WBGene00020891(T28C12.4),WBGene00020892(T28C12.5)" viable FBgn0028067 l(3)S090609 lethal (3) S090609 http://flybase.net/reports/FBgn0028067.html gene 0906/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0262824 CG43195 http://flybase.net/reports/FBgn0262824.html protein_coding_gene CG43195 16-Dec-15 2015_12 FBgn0045498 Gr22d Gustatory receptor 22d http://flybase.net/reports/FBgn0045498.html "FBgn0045493, FBgn0051930" protein_coding_gene 0008527=taste receptor activity 0050912=detection of chemical stimulus involved in sensory perception of taste 0016021=integral component of membrane "CG31930, Gr22dP, Gustatory receptor 2940.2, CR31930, GR22d, Gr2940.2" IPR013604=7TM chemoreceptor CG31930 16-Dec-15 2015_12 FBgn0023549 Mct1 Monocarboxylate transporter 1 http://flybase.net/reports/FBgn0023549.html protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "CG3456, EG:103B4.3" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG3456 16-Dec-15 2015_12 ENSDARG00000042807(zgc:158390) "YNL125C(ESBP6),YKL221W(MCH2)" "WBGene00015676(C10E2.6),WBGene00020168(T02G5.12)" ENSXETG00000005121(SLC16A9) ENSMUSG00000009378(Slc16a12) ENSG00000163053(SLC16A14) FBgn0002813 ms(1)V7 male sterile (1) V7 http://flybase.net/reports/FBgn0002813.html gene 16-Dec-15 2015_12 male sterile FBgn0003246 rgt reduced pigment http://flybase.net/reports/FBgn0003246.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,body color defective" pigment cell FBgn0025740 PlexB Plexin B http://flybase.net/reports/FBgn0025740.html FBgn0024198 protein_coding_gene "0005515=protein binding, 0017154=semaphorin receptor activity" "0097374=sensory neuron axon guidance, 0007411=axon guidance, 0071526=semaphorin-plexin signaling pathway, 0035021=negative regulation of Rac protein signal transduction, 0071678=olfactory bulb axon guidance, 0035025=positive regulation of Rho protein signal transduction, 0008045=motor neuron axon guidance" 0005886=plasma membrane "plex B, plex, CG17245, plexB, unnamed, PLEXB, plexin and met-hepatocyte growth factor receptor-like, Plexin-B, plexin B, plexinB, PlexB, plexin-B, plexin" "IPR016201=Plexin-like fold, IPR031146=Invertebrate plexin-B, IPR013548=Plexin, cytoplasmic RasGAP domain, IPR013783=Immunoglobulin-like fold, IPR002165=Plexin repeat, IPR002909=IPT domain, IPR001627=Sema domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR031148=Plexin family, IPR008936=Rho GTPase activation protein, IPR014756=Immunoglobulin E-set" CG17245 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage >=9 , embryonic stage | early " " myoblast

, neuron

, embryonic central nervous system

,

ubiquitous " "viable,neuroanatomy defective,behavior defective,partially lethal - majority die" "intermediate longitudinal fascicle,MP1 tract,scolopidial neuron,adult olfactory receptor neuron,intersegmental nerve,segmental nerve branch SNa of A1-7,medial longitudinal fascicle,intersegmental nerve branch ISNb of A1-7,RP3 motor neuron" FBgn0021586 DdbP1 Damage-specific DNA-binding protein 1 http://flybase.net/reports/FBgn0021586.html gene "0004520=endodeoxyribonuclease activity, 0003684=damaged DNA binding" "0006296=nucleotide-excision repair, DNA incision, 5'-to lesion, 0006295=nucleotide-excision repair, DNA incision, 3'-to lesion" 0005634=nucleus D-DDB P1 16-Dec-15 2015_12 FBgn0005557 l(3)89Ea lethal (3) 89Ea http://flybase.net/reports/FBgn0005557.html "FBgn0002367, FBgn0002438" gene "lbl, lethal-left-of-Bithorax, lethal bithorax left, llB, l(3)lb, l(3)M182, llb, l(3)lB" 16-Dec-15 2015_12 "lethal,recessive" FBgn0036323 CG14118 http://flybase.net/reports/FBgn0036323.html protein_coding_gene "0046872=metal ion binding, 0016787=hydrolase activity, 0003676=nucleic acid binding" "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG14118 16-Dec-15 2015_12 "ENSDARG00000063613,ENSDARG00000071216,ENSDARG00000071224(si:ch211-133n4.4),ENSDARG00000071223(zgc:158445),ENSDARG00000063044,ENSDARG00000068523,ENSDARG00000069190(zgc:172339),ENSDARG00000068065,ENSDARG00000061611(LOC556323),ENSDARG00000060913,ENSDARG00000061822,ENSDARG00000070242(zgc:171534)" "viable,fertile" FBgn0028043 l(3)S098105 lethal (3) S098105 http://flybase.net/reports/FBgn0028043.html gene 0981/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0028235 l(3)S003220 lethal (3) S003220 http://flybase.net/reports/FBgn0028235.html gene "0797/09, 0016/04, 0248/36, 0032/20" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0039946 ATbp (A+T)-stretch binding protein http://flybase.net/reports/FBgn0039946.html "FBgn0058145, FBan0017172" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter" "CG40145, CG17172, ATBP" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG17172 16-Dec-15 2015_12 FBgn0031227 CG3709 http://flybase.net/reports/FBgn0031227.html FBgn0063788 protein_coding_gene "0009982=pseudouridine synthase activity, 0003723=RNA binding" 0001522=pseudouridine synthesis anon-WO0257455.7 "IPR020103=Pseudouridine synthase, catalytic domain" CG3709 16-Dec-15 2015_12 WBGene00012998(Y48C3A.20) ENSMUSG00000020280(Pus10) ENSG00000162927(PUS10) viable DRSC00629 K -0.770852368 0.174641344 0.112657422 -0.169489653 -1.562865549 -0.19446947 FBgn0051693 CG31693 http://flybase.net/reports/FBgn0051693.html "FBan0031693, FBgn0047305" protein_coding_gene 0005215=transporter activity "0055085=transmembrane transport, 0006810=transport" 0016021=integral component of membrane BcDNA:GH25177 IPR004680=Citrate transporter-like domain CG31693 16-Dec-15 2015_12 viable FBgn0040870 CG12454 http://flybase.net/reports/FBgn0040870.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036547 CG17032 http://flybase.net/reports/FBgn0036547.html protein_coding_gene CG17032 16-Dec-15 2015_12 viable FBgn0264564 CR43936 http://flybase.net/reports/FBgn0264564.html non_protein_coding_gene CG43936 CR43936 16-Dec-15 2015_12 FBgn0052794 CG32794 http://flybase.net/reports/FBgn0052794.html protein_coding_gene 16-Dec-15 2015_12 DRSC24423 EK -0.224904712 1.101181603 2.568057973 -0.36617677 -0.053480751 1.660054052 FBgn0000527 e ebony http://flybase.net/reports/FBgn0000527.html protein_coding_gene 0003833=beta-alanyl-dopamine synthase activity "0001692=histamine metabolic process, 0042440=pigment metabolic process, 0043042=amino acid adenylylation by nonribosomal peptide synthase, 0048067=cuticle pigmentation, 0007623=circadian rhythm, 0048066=developmental pigmentation, 0006583=melanin biosynthetic process from tyrosine, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0042417=dopamine metabolic process, 0048022=negative regulation of melanin biosynthetic process, 0045475=locomotor rhythm, 0007593=chitin-based cuticle sclerotization" 0005737=cytoplasm "NBAD-synthase, ebony, Ebony, CG3331" "IPR009081=Acyl carrier protein-like, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site, IPR025110=AMP-binding enzyme C-terminal domain" CG3331 16-Dec-15 2015_12 YBR115C(LYS2) " adult stage , larval stage | third instar , embryonic stage -- adult stage " " adult brain

, lamina

, ventral nerve cord | restricted

, larval brain | restricted

, thoracico-abdominal ganglion

, medulla

" "visible,recessive,locomotor rhythm defective,body color defective,neurophysiology defective,visual behavior defective,wild-type,optomotor response defective,viable,semidominant,reduced,heat stress response defective" "trident,adult cuticle,wing,synaptic vesicle,photoreceptor cell,embryonic/larval spiracle,retina,mesothoracic tergum" FBgn0000478 DNase2 Deoxyribonuclease 2 http://flybase.net/reports/FBgn0000478.html gene 0004530=deoxyribonuclease I activity "dnase2, acid DNase" 16-Dec-15 2015_12 FBgn0039836 CG1750 http://flybase.net/reports/FBgn0039836.html protein_coding_gene 0004479=methionyl-tRNA formyltransferase activity "0071951=conversion of methionyl-tRNA to N-formyl-methionyl-tRNA, 0009058=biosynthetic process" "IPR011034=Formyl transferase, C-terminal-like, IPR005794=Methionyl-tRNA formyltransferase, IPR002376=Formyl transferase, N-terminal, IPR005793=Formyl transferase, C-terminal, IPR015518=Methionine tRNA Formyltransferase-like" CG1750 16-Dec-15 2015_12 ENSDARG00000005448(zgc:152651) YBL013W(FMT1) ENSXETG00000006652(MTFMT) ENSMUSG00000059183(Mtfmt) ENSG00000103707(MTFMT) DRSC15240 IE 3.230558066 0.826541851 2.519156785 -0.80312832 -0.269521837 0.001367694 FBgn0267503 2SrRNA:CR45843 2S ribosomal RNA:CR45843 http://flybase.net/reports/FBgn0267503.html rRNA_gene CR45843 CR45843 16-Dec-15 2015_12 FBgn0062588 Mod(var)1650 Mod(var)1650 http://flybase.net/reports/FBgn0062588.html gene 0006342=chromatin silencing 1650 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0045967 Tabor\sORF sORF http://flybase.net/reports/FBgn0045967.html transposable_element_gene Pilgrim\sORF 16-Dec-15 2015_12 FBgn0026753 Vha13 Vacuolar H+ ATPase 13kD subunit http://flybase.net/reports/FBgn0026753.html "FBgn0010857, FBgn0061454" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0016820=hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances" "0015991=ATP hydrolysis coupled proton transport, 0001700=embryonic development via the syncytial blastoderm, 0015992=proton transport" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0016471=vacuolar proton-transporting V-type ATPase complex, 0033181=plasma membrane proton-transporting V-type ATPase complex" "VhaG, l(3)05113, Vacuolar H[+] ATPase G-subunit, vha13, chr3R:15469897..15470039, BcDNA:AT14009, CG6213, ATP6V1G" IPR005124=Vacuolar (H+)-ATPase G subunit CG6213 16-Dec-15 2015_12 ENSDARG00000022315(atp6v1g1) YHR039C-A(VMA10) WBGene00006919(vha-10) ENSXETG00000009966(ATP6V1G3) "ENSMUSG00000039105(Atp6v1g1),ENSMUSG00000024403(Atp6v1g2),ENSMUSG00000026394(Atp6v1g3)" "ENSG00000136888(ATP6V1G1),ENSG00000206334,ENSG00000213760(ATP6V1G2),ENSG00000206445,ENSG00000151418(ATP6V1G3)" "lethal,sterile,partially lethal,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/first instar larval cuticle,head,Malpighian tubule" DRSC16895 E -0.237432974 0.343555388 2.437103191 -1.222893602 0.460308761 0.563675719 FBgn0259230 lectin-22C lectin-22C http://flybase.net/reports/FBgn0259230.html "FBgn0040105, FBgn0031385, FBgn0259191" protein_coding_gene "0005534=galactose binding, 0030246=carbohydrate binding" "CG42295, Lectin, AC 004716A, AC004716a, Lectin 22C, CG15378, Lectin22C" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG42295 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000036655(Colec11),ENSMUSG00000038591(Colec10),ENSMUSG00000021795(Sftpd),ENSMUSG00000024863(Mbl2),ENSMUSG00000037780(Mbl1)" "ENSG00000118004(COLEC11),ENSG00000220191,ENSG00000165471(MBL2),ENSG00000184374(COLEC10),ENSG00000133661(SFTPD),ENSG00000182314,ENSG00000122854,ENSG00000122852(SFTPA1),ENSG00000185303(SFTPA2)" FBgn0281845 BG02222 http://flybase.net/reports/FBgn0281845.html gene 16-Dec-15 2015_12 FBgn0004609 NaDg ë_ N-acetyl D-glucosaminidase http://flybase.net/reports/FBgn0004609.html gene 0016231=beta-N-acetylglucosaminidase activity 0006036=cuticle chitin catabolic process "GlcNAc'ase, beta-N-acetylglucosaminidase, HEXOS-1, beta-D-hexosaminidaseI" 16-Dec-15 2015_12 FBgn0259740 CG42394 http://flybase.net/reports/FBgn0259740.html protein_coding_gene CG42394 16-Dec-15 2015_12 FBgn0014076 Vm32E Vitelline membrane 32E http://flybase.net/reports/FBgn0014076.html "FBgn0003981, FBgn0003982" protein_coding_gene 0008316=structural constituent of vitelline membrane 0007305=vitelline membrane formation involved in chorion-containing eggshell formation 0005615=extracellular space "VMP32E, Vm32Ea, Vm3, VM321, VM32E, CG16874, Vm32Ec" IPR013135=Vitelline membrane cysteine-rich domain CG16874 16-Dec-15 2015_12 " adult stage | female , adult stage && oogenesis stage | stage S10 " " organism

, follicle cell

" "viable,fertile" DRSC03474 E 0.801598598 -0.123650084 2.282082291 -0.942289365 -0.739870786 -0.966476544 FBgn0024676 l(2)k00312 lethal (2) k00312 http://flybase.net/reports/FBgn0024676.html gene 12-Mar 16-Dec-15 2015_12 "lethal,recessive" FBgn0058090 CG40090 http://flybase.net/reports/FBgn0058090.html protein_coding_gene 16-Dec-15 2015_12 FBgn0061178 ap::Bx ap::Bx http://flybase.net/reports/FBgn0061178.html engineered_fusion_gene 16-Dec-15 2015_12 visible "wing margin,ectopic,wing,ventral compartment,wing vein,wing vein L5,posterior crossvein,dorsal compartment,supernumerary,wing disc" FBgn0060563 l(3)S096703 lethal (3) S096703 http://flybase.net/reports/FBgn0060563.html gene 0967/03 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0035787 CG8543 http://flybase.net/reports/FBgn0035787.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle IPR022727=Pupal cuticle protein C1 CG8543 16-Dec-15 2015_12 viable FBgn0030583 CG14410 http://flybase.net/reports/FBgn0030583.html protein_coding_gene CG14410 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0262790 CG43171 http://flybase.net/reports/FBgn0262790.html protein_coding_gene "MIP03715, MIP03715_ORF_1" CG43171 16-Dec-15 2015_12 FBgn0003555 su(dpyov) suppressor of dumpyoblique-vortex http://flybase.net/reports/FBgn0003555.html gene "su(dp[ov]), su(dp)" 16-Dec-15 2015_12 "viable,fertile" FBgn0051579 tRNA:CR31579 transfer RNA:CR31579 http://flybase.net/reports/FBgn0051579.html FBgn0060286 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002708.trna15-AlaAGC, chr3R.trna21-AlaAGC, tRNA[[Ala]], CR31579, tRNA:A:AGC:AE002708-c" CR31579 16-Dec-15 2015_12 FBgn0034681 CG9308 http://flybase.net/reports/FBgn0034681.html protein_coding_gene 0005215=transporter activity "0048193=Golgi vesicle transport, 0016050=vesicle organization, 0006810=transport" "0016021=integral component of membrane, 0030142=Golgi to ER transport vesicle" p24 "IPR015720=TMP21-related, IPR009038=GOLD domain" CG9308 16-Dec-15 2015_12 YGL200C(EMP24) "viable,visible,partially lethal - majority die" trichogen cell DRSC28962 K 0.19099717 -0.043049805 -0.621223135 0.258237755 1.64036442 1.255758184 FBgn0259660 B0499 http://flybase.net/reports/FBgn0259660.html gene 16-Dec-15 2015_12 "lethal,visible" wing vein FBgn0030396 CG2556 http://flybase.net/reports/FBgn0030396.html protein_coding_gene CG2556 16-Dec-15 2015_12 "viable,fertile" FBgn0044510 mRpS5 mitochondrial ribosomal protein S5 http://flybase.net/reports/FBgn0044510.html "FBan0040049, FBgn0047104, FBgn0058049" protein_coding_gene "0003723=RNA binding, 0003735=structural constituent of ribosome" 0006412=translation 0005763=mitochondrial small ribosomal subunit "BcDNA:RE47909, CG40049, MRP-S5, MrpS5" "IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR013810=Ribosomal protein S5, N-terminal, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR014720=Double-stranded RNA-binding domain, IPR005324=Ribosomal protein S5, C-terminal, IPR000851=Ribosomal protein S5, IPR018192=Ribosomal protein S5, N-terminal, conserved site" CG40049 16-Dec-15 2015_12 ENSDARG00000062209(mrps5) WBGene00008452(mrps-5) ENSXETG00000022440(MRPS5) ENSMUSG00000027374(Mrps5) ENSG00000144029(MRPS5) FBgn0011152 l(1)Q228 lethal (1) Q228 http://flybase.net/reports/FBgn0011152.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0045065 bst brain storming http://flybase.net/reports/FBgn0045065.html gene 0007420=brain development 16-Dec-15 2015_12 viable "ellipsoid body,mushroom body beta-lobe" FBgn0259732 tal-3A http://flybase.net/reports/FBgn0259732.html protein_coding_gene "0007015=actin filament organization, 0002009=morphogenesis of an epithelium" "tal, CG42386, ORF3, ORF 3A, Dm3, Pep3, pri" CG42386 16-Dec-15 2015_12 FBgn0267274 CR45710 http://flybase.net/reports/FBgn0267274.html non_protein_coding_gene CR45710 16-Dec-15 2015_12 FBgn0028655 anon-35F-36Ab anon-35F-36Ab http://flybase.net/reports/FBgn0028655.html gene anon-35F/36Ab 16-Dec-15 2015_12 FBgn0013281 Inr-Adh Inverse-regulator-Adh http://flybase.net/reports/FBgn0013281.html gene Inr-A 16-Dec-15 2015_12 FBgn0033050 Pngl PNGase-like http://flybase.net/reports/FBgn0033050.html protein_coding_gene "0030246=carbohydrate binding, 0000224=peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity" 0006516=glycoprotein catabolic process "0005829=cytosol, 0005737=cytoplasm" "png1, PNGase, CG7865" "IPR018997=PUB domain, IPR002931=Transglutaminase-like, IPR008979=Galactose-binding domain-like, IPR006588=Peptide N glycanase, PAW domain, IPR006567=PUG domain" CG7865 16-Dec-15 2015_12 ENSDARG00000003205(ngly1) WBGene00010160(png-1) ENSXETG00000007285(NGLY1) ENSMUSG00000021785(Ngly1) ENSG00000151092(NGLY1) "partially lethal - majority die,viable,recessive,developmental rate defective,male sterile,female sterile,short lived,fertile" FBgn0022111 l(2)k06917 lethal (2) k06917 http://flybase.net/reports/FBgn0022111.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027093 Aats-arg Arginyl-tRNA synthetase http://flybase.net/reports/FBgn0027093.html FBgn0030698 protein_coding_gene "0004814=arginine-tRNA ligase activity, 0005524=ATP binding" 0006420=arginyl-tRNA aminoacylation "0017101=aminoacyl-tRNA synthetase multienzyme complex, 0005737=cytoplasm" "CG9020, ArgRS, RRS, Arginyl-tRNA Ligase" "IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR005148=Arginyl tRNA synthetase N-terminal domain, IPR008909=DALR anticodon binding, IPR001278=Arginine-tRNA ligase" CG9020 16-Dec-15 2015_12 "ENSDARG00000054530(rars),ENSDARG00000003234" WBGene00004679(rars-1) ENSXETG00000025551(rars) ENSMUSG00000018848(Rars) ENSG00000113643(RARS) embryonic stage " embryonic/larval salivary gland

,

ubiquitous " lethal FBgn0000669 fliC flightless C http://flybase.net/reports/FBgn0000669.html gene 0007629=flight behavior 16-Dec-15 2015_12 "flightless,recessive,heat sensitive,visible,lethal,maternal effect,female sterile,locomotor behavior defective,flight defective,behavior defective" FBgn0039648 CG14515 http://flybase.net/reports/FBgn0039648.html protein_coding_gene IPR002861=Reeler domain CG14515 16-Dec-15 2015_12 FBgn0261818 CG42760 http://flybase.net/reports/FBgn0261818.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262846 CG43210 http://flybase.net/reports/FBgn0262846.html protein_coding_gene CG43210 16-Dec-15 2015_12 FBgn0000316 cin cinnamon http://flybase.net/reports/FBgn0000316.html FBgn0026665 protein_coding_gene "0006777=Mo-molybdopterin cofactor biosynthetic process, 0001700=embryonic development via the syncytial blastoderm" "EG:BACR37P7.3, CG2945, fs(1)M50, l(1)G0142, CIN, l(1)1Ae" "IPR005111=MoeA, C-terminal, domain IV, IPR001453=MoaB/Mog domain, IPR008284=Molybdenum cofactor biosynthesis, conserved site, IPR005110=MoeA, N-terminal and linker domain" CG2945 16-Dec-15 2015_12 WBGene00003384(moc-1) ENSXETG00000011223(GPHN) ENSMUSG00000047454(Gphn) ENSG00000171723(GPHN) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,fertile,maternal effect,female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,eye color defective,some die during embryonic stage,heat sensitive" "pigment cell,egg" FBgn0250849 CG32388 http://flybase.net/reports/FBgn0250849.html "FBgn0045806, FBgn0044595, FBgn0047300, FBgn0052388, FBgn0063764, FBgn0066867" protein_coding_gene "BEST:GH26265, anon-SAGE:Wang-131, BcDNA:AT03632, anon-WO0140519.36, BcDNA:GH26265" CG32388 16-Dec-15 2015_12 FBgn0066095 MSu331 MSu331 http://flybase.net/reports/FBgn0066095.html gene 16-Dec-15 2015_12 FBgn0085521 CG40813 http://flybase.net/reports/FBgn0085521.html FBan0040813 protein_coding_gene "0000166=nucleotide binding, 0003676=nucleic acid binding" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG40813 16-Dec-15 2015_12 ENSDARG00000043666(zgc:109995) YNR054C(ESF2) WBGene00019005(F57B10.8) ENSXETG00000005684(ABT1) ENSMUSG00000036376(Abt1) ENSG00000146109(ABT1) FBgn0036059 nudE nudE http://flybase.net/reports/FBgn0036059.html protein_coding_gene 0008017=microtubule binding "0051642=centrosome localization, 0007080=mitotic metaphase plate congression, 0007060=male meiosis chromosome segregation, 0051298=centrosome duplication, 0007052=mitotic spindle organization, 0007298=border follicle cell migration, 0007294=germarium-derived oocyte fate determination" "0070732=spindle envelope, 0031616=spindle pole centrosome, 0005635=nuclear envelope, 0000776=kinetochore, 0005819=spindle" "NudE, DnudE, CG8104" "IPR006964=NUDE protein, C-terminal" CG8104 16-Dec-15 2015_12 "ENSDARG00000038190(ndel1b),ENSDARG00000010953(ndel1a),ENSDARG00000037900(zgc:114109)" "ENSXETG00000005528(BC080874.1),ENSXETG00000016342(TEgg108o19.1)" "ENSMUSG00000018736(Ndel1),ENSMUSG00000022678(Nde1)" "ENSG00000166579(NDEL1),ENSG00000072864(NDE1)" "viable,visible,body color defective,lethal,recessive,mitotic cell cycle defective" "oocyte,germline clone,trichogen cell,mesothoracic tergum,border follicle cell,somatic clone,condensed chromosome,centrosome,centrosome | supernumerary,spindle,spindle pole,spindle & primary spermatocyte in meiotic metaphase I,centrosome & spermatocyte,nucleus & onion stage spermatid,Nebenkern,condensed chromosomeAC1)" DRSC10962 I 2.09007903 0.507133779 0.603703944 -0.156565923 -0.352377824 0.188493545 FBgn0264287 Su(Mir)1-1A2-2 http://flybase.net/reports/FBgn0264287.html gene 16-Dec-15 2015_12 lethal FBgn0031690 CG7742 http://flybase.net/reports/FBgn0031690.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity IPR000195=Rab-GTPase-TBC domain CG7742 16-Dec-15 2015_12 ENSDARG00000013842(tbc1d19) ENSXETG00000000906(TBC1D19) ENSMUSG00000039178(Tbc1d19) ENSG00000109680(TBC1D19) viable FBgn0030715 Or13a Odorant receptor 13a http://flybase.net/reports/FBgn0030715.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "13F.1, CG12697, dOr13a, DOR38, 13a, or13a" "IPR004117=Olfactory receptor, Drosophila" CG12697 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0013934 Su(Pc)35CD Su(Pc)35CD http://flybase.net/reports/FBgn0013934.html gene "E(Pc)35CD, Su(Pc), E(Pc)28B" 16-Dec-15 2015_12 FBgn0050206 tRNA:CR30206 transfer RNA:CR30206 http://flybase.net/reports/FBgn0050206.html FBgn0060014 tRNA_gene 0033416=UGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002575.trna14-TrpCCA, tRNA:W:CCA:AE002575-d, chr2R.trna58-TrpCCA, CR30206" CR30206 16-Dec-15 2015_12 FBgn0014998 tlr-2 tld-related-2 http://flybase.net/reports/FBgn0014998.html gene 0008233=peptidase activity "0030509=BMP signaling pathway, 0007474=imaginal disc-derived wing vein specification" "tlr, tolloid-related" 16-Dec-15 2015_12 FBgn0013283 Jhbp-63 Juvenile hormone binding protein - 63kD http://flybase.net/reports/FBgn0013283.html gene 16-Dec-15 2015_12 FBgn0037281 CG1277 http://flybase.net/reports/FBgn0037281.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005422 l(1)adl11 lethal (1) adl11 http://flybase.net/reports/FBgn0005422.html gene l(1)adl-11 16-Dec-15 2015_12 "short lived,heat sensitive,lethal" FBgn0002145 l(2)K483 lethal (2) K483 http://flybase.net/reports/FBgn0002145.html gene 16-Dec-15 2015_12 lethal FBgn0037012 Rcd2 Reduction in Cnn dots 2 http://flybase.net/reports/FBgn0037012.html protein_coding_gene 0007099=centriole replication 0005886=plasma membrane "Rcd2, CT15369, Reduction in Cnn Dots 2, CG4786" IPR001007=VWFC domain CG4786 16-Dec-15 2015_12 "viable,fertile" DRSC11756 IEK 1.063383419 -2.281567593 0.719574409 -1.509769336 2.529112857 0.727687531 FBgn0053366 5SrRNA:CR33366 5SrRNA:CR33366 http://flybase.net/reports/FBgn0053366.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33366 CR33366 16-Dec-15 2015_12 FBgn0067087 JK1285 JK1285 http://flybase.net/reports/FBgn0067087.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0028619 l(2)34Ec lethal (2) 34Ec http://flybase.net/reports/FBgn0028619.html gene 16-Dec-15 2015_12 FBgn0086047 snoRNA:Me18S-G894 http://flybase.net/reports/FBgn0086047.html snoRNA_gene "CR34676, Me18S-Gm894" CR34676 16-Dec-15 2015_12 FBgn0039964 CG18246 http://flybase.net/reports/FBgn0039964.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038512 CG14330 http://flybase.net/reports/FBgn0038512.html protein_coding_gene CG14330 16-Dec-15 2015_12 viable FBgn0030164 CG1889 http://flybase.net/reports/FBgn0030164.html protein_coding_gene "Fibrinogen-related protein, AAF46536, FBpp0071344, AAN09619, FBpp0071343" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG1889 16-Dec-15 2015_12 "ENSDARG00000068369(angptl2),ENSDARG00000024030(zgc:194138),ENSDARG00000020265(angptl6),ENSDARG00000027582(angptl7)" "WBGene00016769(C49C8.5),WBGene00012782(Y43C5A.2)" "ENSMUSG00000004105(Angptl2),ENSMUSG00000033544(Angptl1),ENSMUSG00000038742(Angptl6)" "ENSG00000136859(ANGPTL2),ENSG00000130812(ANGPTL6)" viable FBgn0041767 anon-d43 anon-d43 http://flybase.net/reports/FBgn0041767.html gene d43 16-Dec-15 2015_12 FBgn0030829 CG12998 http://flybase.net/reports/FBgn0030829.html FBgn0061372 protein_coding_gene "CT32204, BcDNA:RH61745" CG12998 16-Dec-15 2015_12 viable FBgn0013307 Odc1 Ornithine decarboxylase 1 http://flybase.net/reports/FBgn0013307.html FBgn0002984 protein_coding_gene 0004586=ornithine decarboxylase activity 0006596=polyamine biosynthetic process "dodc1, CG8721, Ornithine decarboxylase-1, Odc-1, ornithine decarboxylase" "IPR002433=Ornithine decarboxylase, IPR009006=Alanine racemase/group IV decarboxylase, C-terminal, IPR029066=PLP-binding barrel, IPR022653=Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site, IPR022643=Orn/DAP/Arg decarboxylase 2, C-terminal, IPR022657=Orn/DAP/Arg decarboxylase 2, conserved site, IPR000183=Ornithine/DAP/Arg decarboxylase, IPR022644=Orn/DAP/Arg decarboxylase 2, N-terminal" CG8721 16-Dec-15 2015_12 ENSDARG00000007377(odc1) YKL184W(SPE1) WBGene00003844(odc-1) "ENSXETG00000003519(odc1),ENSXETG00000007373(TNeu085h23.1),ENSXETG00000004118(azin1)" "ENSMUSG00000011179(Odc1),ENSMUSG00000028789(Adc),ENSMUSG00000037458(Azin1),ENSMUSG00000023120(Gm853)" "ENSG00000115758(ODC1),ENSG00000142920(ADC),ENSG00000155096(AZIN1)" "delayed aging,memory defective,viable,visible,body color defective" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0001854 l(1)tsUC32 lethal (1) tsUC32 http://flybase.net/reports/FBgn0001854.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0029878 Pat1 Protein interacting with APP tail-1 http://flybase.net/reports/FBgn0029878.html protein_coding_gene "0006909=phagocytosis, 0060632=regulation of microtubule-based movement, 0045451=pole plasm oskar mRNA localization, 0007018=microtubule-based movement" 0005871=kinesin complex "pat1, PAT1, CG10695" "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG10695 16-Dec-15 2015_12 ENSDARG00000007566(appbp2) ENSXETG00000013509(APPBP2) ENSMUSG00000018481(Appbp2) ENSG00000062725(APPBP2) "viable,fertile" FBgn0062576 Mod(var)E113 Mod(var)E113 http://flybase.net/reports/FBgn0062576.html gene 0006342=chromatin silencing E113 16-Dec-15 2015_12 "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0026721 fat-spondin fat-spondin http://flybase.net/reports/FBgn0026721.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005576=extracellular region "CT21501, Dmel_CG6953, Fat-spondin, CG6953" "IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR009465=Spondin, N-terminal, IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR002861=Reeler domain, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site" CG6953 16-Dec-15 2015_12 WBGene00006893(spon-1) ENSXETG00000009063(SPON1) viable FBgn0000891 fs(1)M89 female sterile (1) M89 http://flybase.net/reports/FBgn0000891.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0015421 l(1)17Ag lethal (1) 17Ag http://flybase.net/reports/FBgn0015421.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261792 snRNP-U1-C small ribonucleoprotein particle U1 subunit C http://flybase.net/reports/FBgn0261792.html "FBgn0038667, FBgn0064828, FBgn0022969" protein_coding_gene "0008270=zinc ion binding, 0003729=mRNA binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis, 0007052=mitotic spindle organization, 0000387=spliceosomal snRNP assembly" "0030532=small nuclear ribonucleoprotein complex, 0005685=U1 snRNP, 0005634=nucleus, 0005692=U11 snRNP" "snRNPC, BcDNA:RH29440, U1C, snRNP-U1, CG5454, dU1-C, C" "IPR013085=Zinc finger, U1-C type, IPR003604=Zinc finger, U1-type, IPR017340=U1 small nuclear ribonucleoprotein C, IPR000690=Zinc finger, C2H2-type matrin" CG5454 16-Dec-15 2015_12 ENSDARG00000009871(snrpc) WBGene00017238(F08B4.7) ENSXETG00000024721(SNRPC) ENSMUSG00000024217(Snrpc) ENSG00000124562(SNRPC) DRSC15804 I 4.689201368 1.488234775 -0.191911559 0.703537372 -0.20867155 0.11260908 FBgn0065885 l(2)SH0228 lethal (2) SH0228 http://flybase.net/reports/FBgn0065885.html gene l(2)SH2 0228 16-Dec-15 2015_12 "lethal,recessive" FBgn0000175 bf brief http://flybase.net/reports/FBgn0000175.html gene 16-Dec-15 2015_12 "male sterile,viable,female fertile,poor,visible" macrochaeta FBgn0002281 l(3)73Af lethal (3) 73Af http://flybase.net/reports/FBgn0002281.html gene l(3)133.52 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0265417 CG44329 http://flybase.net/reports/FBgn0265417.html protein_coding_gene lincRNA.951 CG44329 16-Dec-15 2015_12 FBgn0069206 l(2)46Dh lethal (2) 46Dh http://flybase.net/reports/FBgn0069206.html gene Complementation group Z 16-Dec-15 2015_12 lethal FBgn0083050 snoRNA:ë¬18S-1377b snoRNA:ë¬18S-1377b http://flybase.net/reports/FBgn0083050.html snoRNA_gene "psi18S-1377b, CR34628, Psi18S-1377b" CR34628 16-Dec-15 2015_12 FBgn0000534 E(ade2) Enhancer of ade2 http://flybase.net/reports/FBgn0000534.html gene 16-Dec-15 2015_12 FBgn0060320 l(3)S147114 lethal (3) S147114 http://flybase.net/reports/FBgn0060320.html FBgn0060315 gene "l(3)S147506a, 1471/14, 1475/06" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033900 CG8257 http://flybase.net/reports/FBgn0033900.html protein_coding_gene "0005524=ATP binding, 0004817=cysteine-tRNA ligase activity" 0006423=cysteinyl-tRNA aminoacylation 0005829=cytosol "IPR024909=Cysteinyl-tRNA synthetase/mycothiol ligase, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR015273=Cysteinyl-tRNA synthetase, class Ia, DALR, IPR015803=Cysteine-tRNA ligase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG8257 16-Dec-15 2015_12 ENSXETG00000008210(Q6DJ95_XENTR) ENSMUSG00000056228(Cars2) ENSG00000134905(CARS2) "viable,visible" trichogen cell FBgn0060314 l(3)S147703 lethal (3) S147703 http://flybase.net/reports/FBgn0060314.html gene 1477/03 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0065970 l(2)45Da lethal (2) 45Da http://flybase.net/reports/FBgn0065970.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037520 CG18268 http://flybase.net/reports/FBgn0037520.html protein_coding_gene "IPR011021=Arrestin-like, N-terminal, IPR014756=Immunoglobulin E-set" CG18268 16-Dec-15 2015_12 viable FBgn0036133 CG7638 http://flybase.net/reports/FBgn0036133.html protein_coding_gene IPR019395=Transmembrane protein 161A/B CG7638 16-Dec-15 2015_12 "ENSDARG00000055989(tmem161b),ENSDARG00000012790(tmem161a)" WBGene00013601(Y87G2A.13) "ENSXETG00000011719(TMEM161B),ENSXETG00000014335(TEgg031b04.1)" "ENSMUSG00000035762(Tmem161b),ENSMUSG00000002342(Tmem161a)" "ENSG00000164180(TMEM161B),ENSG00000064545(TMEM161A)" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC22684 IK 2.884542988 0.755356983 1.302120481 1.33804857 0.993360314 1.543866353 FBgn0052767 CG32767 http://flybase.net/reports/FBgn0052767.html "FBgn0029742, FBgn0029743, FBgn0047261" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "BcDNA:GM08530, CG5113, i7, LD34931, CG5086" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG32767 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC18386 IEK 2.425877083 1.682998704 0.553123392 -1.80458811 1.799204937 2.693785 FBgn0052740 tRNA:CR32740 transfer RNA:CR32740 http://flybase.net/reports/FBgn0052740.html FBgn0060235 tRNA_gene 0033402=UUC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chrX.trna25-PheGAA, CR32740, tRNA:F:GAA:AE002566-b, AE002566.trna5-PheGAA" CR32740 16-Dec-15 2015_12 FBgn0032168 CG13126 http://flybase.net/reports/FBgn0032168.html FBgn0062171 protein_coding_gene "0005507=copper ion binding, 0008168=methyltransferase activity" 0006412=translation anon-WO0118547.208 "IPR007533=Cytochrome c oxidase assembly protein CtaG/Cox11, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR015324=Ribosomal protein Rsm22, bacterial-type" CG13126 16-Dec-15 2015_12 YKL155C(RSM22) WBGene00009305(F32A7.4) ENSXETG00000001747(METT11D1) ENSMUSG00000004561(Mett11d1) ENSG00000165792(METTL17) FBgn0261357 CG42634 http://flybase.net/reports/FBgn0261357.html "FBgn0032659, FBan0015149" protein_coding_gene CG15149 CG42634 16-Dec-15 2015_12 FBgn0028021 l(3)S104018b lethal (3) S104018b http://flybase.net/reports/FBgn0028021.html gene "1040/18, l(3)S104018" 16-Dec-15 2015_12 "lethal,recessive" FBgn0025484 l(3)Ax18 lethal (3) Ax18 http://flybase.net/reports/FBgn0025484.html gene Ax18 16-Dec-15 2015_12 "lethal,recessive" FBgn0028520 CG4891 http://flybase.net/reports/FBgn0028520.html FBgn0027927 protein_coding_gene "DS04095.1, BG:DS04095.1" CG4891 16-Dec-15 2015_12 viable FBgn0030501 BthD BthD selenoprotein http://flybase.net/reports/FBgn0030501.html protein_coding_gene 0008430=selenium binding "0051775=response to redox state, 0045454=cell redox homeostasis, 0007436=larval salivary gland morphogenesis" "0005737=cytoplasm, 0005794=Golgi apparatus" "dSelH, SelH, CG11177, BthDselenoprotein, dselM, dselH" "IPR011893=Selenoprotein, Rdx type" CG11177 16-Dec-15 2015_12 "decreased cell size,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,mesothoracic tergum" FBgn0002342 l(3)87Bk lethal (3) 87Bk http://flybase.net/reports/FBgn0002342.html gene l(3)ck23 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0002127 l(2)IP85 lethal (2) IP85 http://flybase.net/reports/FBgn0002127.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,embryonic/first instar larval cuticle" FBgn0022242 l(2)k02205 lethal (2) k02205 http://flybase.net/reports/FBgn0022242.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0053402 5SrRNA:CR33402 5SrRNA:CR33402 http://flybase.net/reports/FBgn0053402.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33402 CR33402 16-Dec-15 2015_12 FBgn0011910 tRNA:L3:49Fb transfer RNA:leu:49Fb http://flybase.net/reports/FBgn0011910.html "FBgn0003789, FBgn0050248, FBgn0050508, FBgn0060162" tRNA_gene "0033404=UUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:leu3:49Fb, leu-b, tRNA[Leu], AE002787.trna41-LeuCAA, tRNA:L:CAA:AE002787-b, chr2R.trna23-LeuCAA, DtL[b], CR30248, CR30508, tRNA[LEU]" CR30508 16-Dec-15 2015_12 male sterile spermatozoon FBgn0060855 l(3)S048219b lethal (3) S048219b http://flybase.net/reports/FBgn0060855.html gene 0482/19 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0083282 E(smoDN)219 Enhancer of smoDN 219 http://flybase.net/reports/FBgn0083282.html gene 16-Dec-15 2015_12 FBgn0038784 CG4362 http://flybase.net/reports/FBgn0038784.html protein_coding_gene 0019028=viral capsid "IPR004302=Chitin-binding, domain 3" CG4362 16-Dec-15 2015_12 "viable,fertile" FBgn0066360 l(1)8Da lethal (1) 8Da http://flybase.net/reports/FBgn0066360.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038611 CG14309 http://flybase.net/reports/FBgn0038611.html protein_coding_gene "0016798=hydrolase activity, acting on glycosyl bonds" "0016020=membrane, 0005811=lipid particle" "IPR005199=Glycoside hydrolase, family 79" CG14309 16-Dec-15 2015_12 viable FBgn0050065 CG30065 http://flybase.net/reports/FBgn0050065.html FBgn0061448 protein_coding_gene BcDNA:AT19876 CG30065 16-Dec-15 2015_12 viable FBgn0052824 CG32824 http://flybase.net/reports/FBgn0052824.html FBgn0042176 protein_coding_gene CG18859 16-Dec-15 2015_12 FBgn0260971 CG42594 http://flybase.net/reports/FBgn0260971.html "FBgn0029731, FBgn0052771, FBgn0029732, FBgn0052770" protein_coding_gene 0005267=potassium channel activity 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "CG32771, CG6952, CG32770, CG15470" "IPR003280=Two pore domain potassium channel, IPR013099=Potassium channel domain" CG42594 16-Dec-15 2015_12 DRSC17363 I 2.331603864 -0.262070574 0.128787111 0.28027347 0.049207114 -0.391003505 FBgn0005760 l(1)TK404 lethal (1) TK404 http://flybase.net/reports/FBgn0005760.html gene l404 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0082624 S(CycEJP)3.4 S(CycEJP)3.4 http://flybase.net/reports/FBgn0082624.html gene 3.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0038846 CG5697 http://flybase.net/reports/FBgn0038846.html FBgn0062946 protein_coding_gene BcDNA:RH32180 CG5697 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260342 GSd033 http://flybase.net/reports/FBgn0260342.html gene 16-Dec-15 2015_12 "wild-type,lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0000889 fs(1)M87 female sterile (1) M87 http://flybase.net/reports/FBgn0000889.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0266233 CR44928 http://flybase.net/reports/FBgn0266233.html non_protein_coding_gene lincRNA.687 CR44928 16-Dec-15 2015_12 FBgn0086915 Mst77F Male-specific transcript 77F http://flybase.net/reports/FBgn0086915.html "FBgn0000093, FBgn0002839" protein_coding_gene "0035092=sperm chromatin condensation, 0035093=spermatogenesis, exchange of chromosomal proteins, 0007290=spermatid nucleus elongation" "0005634=nucleus, 0005874=microtubule, 0036126=sperm flagellum, 0000785=chromatin" "ms(3)nc3, R1-18c, male sterile (3) nc3, nc3, CG3354, 18c, mst77F" CG3354 16-Dec-15 2015_12 pupal stage&&adult stage "male sterile,viable,fertile,partially lethal - majority die,some die during pupal stage" "nucleus & late spermatidri-79c),chromatin & late spermatidri-79c),spermatid,nucleus & late spermatid,chromatin & late spermatid,nucleus & spermatozoon" FBgn0035867 CG13671 http://flybase.net/reports/FBgn0035867.html protein_coding_gene IPR012336=Thioredoxin-like fold CG13671 16-Dec-15 2015_12 ENSXETG00000016620(TXNDC11) ENSMUSG00000022498(Txndc11) ENSG00000153066(TXNDC11) "viable,fertile" FBgn0043012 AP-2ìÄ "Adaptor Protein complex 2, ìÄ subunit" http://flybase.net/reports/FBgn0043012.html "FBgn0038875, FBgn0043468" protein_coding_gene 0008565=protein transporter activity "0007269=neurotransmitter secretion, 0006897=endocytosis, 0006886=intracellular protein transport, 0016183=synaptic vesicle coating, 0006901=vesicle coating, 0022008=neurogenesis" "0030122=AP-2 adaptor complex, 0008021=synaptic vesicle, 0030135=coated vesicle" "CG6056, AP-2sigma, aps2, AP2, cg6056, sigma2, AP-2 sigma" "IPR000804=Clathrin adaptor complex, small chain, IPR011012=Longin-like domain, IPR016635=Adaptor protein complex, sigma subunit, IPR022775=AP complex, mu/sigma subunit, IPR027156=AP-2 complex subunit sigma" CG6056 16-Dec-15 2015_12 ENSDARG00000026967(zgc:65827) YJR058C(APS2) WBGene00000157(aps-2) ENSXETG00000018283(ap2s1) ENSMUSG00000008036(Ap2s1) ENSG00000042753(AP2S1) "neuroanatomy defective,recessive,somatic clone,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,somatic clone,supernumerary,embryonic/larval brain" FBgn0083275 E(smoDN)2577 Enhancer of smoDN 2577 http://flybase.net/reports/FBgn0083275.html gene 16-Dec-15 2015_12 FBgn0083087 hys hyperswirl http://flybase.net/reports/FBgn0083087.html gene "0008340=determination of adult lifespan, 0007005=mitochondrion organization" 16-Dec-15 2015_12 "stress response defective,short lived,recessive,flight defective" flight muscle & mitochondrial inner membrane FBgn0051880 CG31880 http://flybase.net/reports/FBgn0051880.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065763 l(2)SH0476 lethal (2) SH0476 http://flybase.net/reports/FBgn0065763.html gene l(2)SH2 0476 16-Dec-15 2015_12 "lethal,recessive" FBgn0082987 snoRNA:ë¬28S-2444 snoRNA:ë¬28S-2444 http://flybase.net/reports/FBgn0082987.html snoRNA_gene "CR34546, psi28s-2444, chr2R:14957975..14958113, Psi 28S-2444" CR34546 16-Dec-15 2015_12 FBgn0029882 CG3226 http://flybase.net/reports/FBgn0029882.html protein_coding_gene 0007507=heart development 0005875=microtubule associated complex Q9W3Y3 "IPR007052=CS domain, IPR007699=SGS domain, IPR008978=HSP20-like chaperone, IPR015120=Siah interacting protein, N-terminal" CG3226 16-Dec-15 2015_12 ENSDARG00000014731(cacybp) ENSXETG00000020044(cacybp) ENSMUSG00000014226(Cacybp) ENSG00000116161(CACYBP) viable FBgn0020897 Su(osk)G23 Suppressor of oskar G23 http://flybase.net/reports/FBgn0020897.html gene G23 16-Dec-15 2015_12 FBgn0038839 Ktl Kctd12-like http://flybase.net/reports/FBgn0038839.html protein_coding_gene "0051260=protein homooligomerization, 0008049=male courtship behavior, 0002121=inter-male aggressive behavior, 0090327=negative regulation of locomotion involved in locomotory behavior, 0030431=sleep" 0005886=plasma membrane CG10830 "IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR003131=Potassium channel tetramerisation-type BTB domain" CG10830 16-Dec-15 2015_12 "ENSDARG00000071884,ENSDARG00000067507(kctd8),ENSDARG00000037507(kctd12b),ENSDARG00000053542(kctd12.2),ENSDARG00000020102(kctd16b),ENSDARG00000004648" WBGene00014848(VM106R.1) "ENSXETG00000015471(KCTD12),ENSXETG00000008440(),ENSXETG00000003081()" "ENSMUSG00000051401(Kctd16),ENSMUSG00000037653(Kctd8),ENSMUSG00000041633(Kctd12b)" "ENSG00000178695(KCTD12),ENSG00000183783(KCTD8),ENSG00000183775(KCTD16)" viable FBgn0000963 fs(2)eo4 female sterile (2) eo4 http://flybase.net/reports/FBgn0000963.html gene 0048477=oogenesis "fs(2)eoPB6, fs(2)eo-A" 16-Dec-15 2015_12 "female sterile,male sterile" FBgn0082621 S(CycEJP)43S1 S(CycEJP)43S1 http://flybase.net/reports/FBgn0082621.html gene 43S1 16-Dec-15 2015_12 "lethal,recessive" FBgn0266679 CR45169 http://flybase.net/reports/FBgn0266679.html non_protein_coding_gene CR45169 16-Dec-15 2015_12 FBgn0004118 nAChRë_2 nicotinic Acetylcholine Receptor ë_2 http://flybase.net/reports/FBgn0004118.html protein_coding_gene 0004889=acetylcholine-activated cation-selective channel activity "0006811=ion transport, 0007271=synaptic transmission, cholinergic, 0017085=response to insecticide" "0005887=integral component of plasma membrane, 0005892=acetylcholine-gated channel complex, 0045211=postsynaptic membrane" "beta[[2]], Dbeta2, AcrF, nAcRbeta, nAcr96Ac, nACRbeta, CG6798, second beta-like subunit of Drosophila, nAcRbeta-96A, Acr96Ac, nicotinic Acetylcholine Receptor beta 96A, nACR beta 96A, sbd, SBD, beta2, nAChRbeta2, nAChR, nAcRs" "IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR002394=Nicotinic acetylcholine receptor" CG6798 16-Dec-15 2015_12 "ENSDARG00000057025(chrna2b),ENSDARG00000006602(chrna2a),ENSDARG00000058393(chrna4),ENSDARG00000070724(LOC563696),ENSDARG00000057848,ENSDARG00000054497(LOC568467),ENSDARG00000055559(chrna6)" WBGene00006774(unc-38) ENSXETG00000017553(CHRNA2) "ENSMUSG00000032303(Chrna3),ENSMUSG00000031491(Chrna6),ENSMUSG00000027577(Chrna4),ENSMUSG00000022041(Chrna2)" "ENSG00000101204(CHRNA4),ENSG00000120903(CHRNA2),ENSG00000080644(CHRNA3),ENSG00000147434(CHRNA6)" "chemical resistant,viable,visible" "chaeta,supernumerary" FBgn0265881 CR44670 http://flybase.net/reports/FBgn0265881.html non_protein_coding_gene lincRNA.607 CR44670 16-Dec-15 2015_12 FBgn0036346 CG11251 http://flybase.net/reports/FBgn0036346.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR011234=Fumarylacetoacetase, C-terminal-related" CG11251 16-Dec-15 2015_12 ENSXETG00000004339(fahd2a) "viable,planar polarity defective" FBgn0266931 CR45382 http://flybase.net/reports/FBgn0266931.html non_protein_coding_gene CR45382 16-Dec-15 2015_12 FBgn0267447 CR45797 http://flybase.net/reports/FBgn0267447.html non_protein_coding_gene Mgn94071 CR45797 16-Dec-15 2015_12 FBgn0039300 RpS27 Ribosomal protein S27 http://flybase.net/reports/FBgn0039300.html FBgn0025532 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005811=lipid particle, 0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "Rp S27, anon-EST:Posey295, Q9VBU9_DROME, CG10423" "IPR023407=Ribosomal protein S27e, zinc-binding domain, IPR000592=Ribosomal protein S27e, IPR011332=Zinc-binding ribosomal protein" CG10423 16-Dec-15 2015_12 "ENSDARG00000055475(zgc:73262),ENSDARG00000023298(zgc:109888)" "YKL156W(RPS27A),YHR021C(RPS27B)" WBGene00004496(rps-27) ENSXETG00000024836() "ENSMUSG00000050621(Gm9846),ENSMUSG00000036781(Rps27l)" ENSG00000177954(RPS27) DRSC14244 EK -1.281564695 0.877475399 1.320068678 -2.01867904 1.680337223 3.498688029 FBgn0001536 l(1)14Bb lethal (1) 14Bb http://flybase.net/reports/FBgn0001536.html gene 16-Dec-15 2015_12 lethal FBgn0000574 elyC early C http://flybase.net/reports/FBgn0000574.html gene ely-C 16-Dec-15 2015_12 "lethal,maternal effect,recessive" "embryo,syncytial blastoderm embryo,maternal effect" FBgn0062699 EP1125 EP1125 http://flybase.net/reports/FBgn0062699.html gene EP(X)1125 16-Dec-15 2015_12 FBgn0002703 mei-1029 meiotic 1029 http://flybase.net/reports/FBgn0002703.html gene 1029 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0029053 l(1)G0455 lethal (1) G0455 http://flybase.net/reports/FBgn0029053.html gene 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" FBgn0001469 l(1)8Aa lethal (1) 8Aa http://flybase.net/reports/FBgn0001469.html gene "HC179, l(1)VE709, l(1)JV69" 16-Dec-15 2015_12 "female sterile,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,egg,maternal effect" FBgn0082972 snoRNA:ë¬28S-3316a snoRNA:ë¬28S-3316a http://flybase.net/reports/FBgn0082972.html snoRNA_gene "Psi 28S-3316a, CR34547, Psi28S-3316, Psi28S-3316a, psi28S-3316a" CR34547 16-Dec-15 2015_12 FBgn0264915 CR44106 http://flybase.net/reports/FBgn0264915.html non_protein_coding_gene CR44106 16-Dec-15 2015_12 FBgn0042149 CG18826 http://flybase.net/reports/FBgn0042149.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034657 LBR Lamin B receptor http://flybase.net/reports/FBgn0034657.html protein_coding_gene "0005521=lamin binding, 0004872=receptor activity" "0005637=nuclear inner membrane, 0005635=nuclear envelope" "CG17952, dLBR, lamin-B receptor" IPR001171=Ergosterol biosynthesis ERG4/ERG24 CG17952 16-Dec-15 2015_12 "ENSDARG00000014013(lbr),ENSDARG00000032816(tm7sf2),ENSDARG00000015564(dhcr7)" "ENSXETG00000018551(LBR),ENSXETG00000023319(TM7SF2)" "ENSMUSG00000004880(Lbr),ENSMUSG00000024799(Tm7sf2),ENSMUSG00000058454(Dhcr7)" "ENSG00000143815(LBR),ENSG00000149809(TM7SF2),ENSG00000172893(DHCR7)" viable FBgn0039189 CG18528 http://flybase.net/reports/FBgn0039189.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" 0006400=tRNA modification 0005622=intracellular "IPR005225=Small GTP-binding protein domain, IPR004520=tRNA modification GTPase MnmE, IPR018948=GTP-binding protein TrmE, N-terminal, IPR006073=GTP binding domain, IPR027266=GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1, IPR027368=tRNA modification GTPase MnmE domain 2, IPR025867=MnmE, helical domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG18528 16-Dec-15 2015_12 ENSDARG00000018650(gtpbp3) YMR023C(MSS1) WBGene00009557(F39B2.7) ENSXETG00000013066(GTPBP3) ENSMUSG00000007610(Gtpbp3) ENSG00000130299(GTPBP3) viable FBgn0263983 CG43732 http://flybase.net/reports/FBgn0263983.html protein_coding_gene Dm_3R:78579 CG43732 16-Dec-15 2015_12 FBgn0014958 fliN flightless N http://flybase.net/reports/FBgn0014958.html gene unnamed 16-Dec-15 2015_12 "flightless,recessive" FBgn0038194 Cyp6d5 Cyp6d5 http://flybase.net/reports/FBgn0038194.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG3050, 6d5, cytochrome P450, cyp6d5" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG3050 16-Dec-15 2015_12 "ENSDARG00000037874(LOC558473),ENSDARG00000037873(cyp3c1l2),ENSDARG00000070021(zgc:153269),ENSDARG00000015575(cyp3c1)" YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0020823 l(3)98Dd lethal (3) 98Dd http://flybase.net/reports/FBgn0020823.html gene "l(3)98D-Ed, M33, l(3)M3-3" 16-Dec-15 2015_12 "lethal,recessive" FBgn0261341 verm vermiform http://flybase.net/reports/FBgn0261341.html "FBgn0013991, FBgn0036901" protein_coding_gene "0008061=chitin binding, 0005041=low-density lipoprotein receptor activity, 0004099=chitin deacetylase activity" "0035159=regulation of tube length, open tracheal system, 0005975=carbohydrate metabolic process, 0006030=chitin metabolic process, 0007424=open tracheal system development, 0060439=trachea morphogenesis, 0007632=visual behavior, 0035001=dorsal trunk growth, open tracheal system" 0005576=extracellular region "Vermiform, LCBP1, LDLa domain containing chitin binding protein 1, hlm, helmsman, l(3)76BDx, N63, Verm, CG8756, DmCDA2" "IPR002557=Chitin binding domain, IPR002509=NodB homology domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG8756 16-Dec-15 2015_12 FBgn0026356 Su(SuRaf1)11 Su(SuRaf1)11 http://flybase.net/reports/FBgn0026356.html gene Su[Su(Raf)1]11 16-Dec-15 2015_12 "lethal,recessive" FBgn0053218 CR33218 http://flybase.net/reports/FBgn0053218.html FBgn0029611 non_protein_coding_gene "CT9762, CG2854, CG33218" CR33218 16-Dec-15 2015_12 FBgn0022356 Taf105 TBP-associated factor 105kD http://flybase.net/reports/FBgn0022356.html gene 0017025=TBP-class protein binding 0006383=transcription from RNA polymerase III promoter 0000126=transcription factor TFIIIB complex "TBP-associated factor, dTAF[[III]]105, TBP-associated factor 105kD, TAF" 16-Dec-15 2015_12 FBgn0051923 CG31923 http://flybase.net/reports/FBgn0051923.html FBgn0064789 protein_coding_gene BcDNA:RH63623 16-Dec-15 2015_12 FBgn0005441 l(1)v135 lethal (1) v135 http://flybase.net/reports/FBgn0005441.html gene l(1)135 16-Dec-15 2015_12 FBgn0002414 l(3)DTS1 lethal (3) DTS1 http://flybase.net/reports/FBgn0002414.html gene DTS-1 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,visible" FBgn0024238 Fim Fimbrin http://flybase.net/reports/FBgn0024238.html protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding" 0016321=female meiosis chromosome segregation "0005829=cytosol, 0070938=contractile ring, 0045179=apical cortex" "FIM, fim, CG8649, fimbrin, Plastin" "IPR001589=Actinin-type actin-binding domain, conserved site, IPR018247=EF-Hand 1, calcium-binding site, IPR001715=Calponin homology domain, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG8649 16-Dec-15 2015_12 "ENSDARG00000037655(pls3),ENSDARG00000023188(lcp1),ENSDARG00000039272(pls1)" YDR129C(SAC6) "ENSXETG00000003677(pls3),ENSXETG00000014954(lcp1),ENSXETG00000000598(PLS1)" "ENSMUSG00000049493(Pls1),ENSMUSG00000016382(Pls3),ENSMUSG00000021998(Lcp1)" "ENSG00000102024(PLS3),ENSG00000136167(LCP1),ENSG00000120756(PLS1)" "viable,fertile,meiotic cell cycle defective,dominant,partially lethal - majority die,some die during pupal stage" DRSC20243 I -0.266587214 -1.690036211 -0.615357685 -0.155843439 -0.883148216 -0.136374613 FBgn0266404 CR45044 http://flybase.net/reports/FBgn0266404.html non_protein_coding_gene CR45044 16-Dec-15 2015_12 FBgn0023074 l(1)19Eg lethal (1) 19Eg http://flybase.net/reports/FBgn0023074.html gene B2/32.16 16-Dec-15 2015_12 "lethal,recessive" FBgn0039519 Cyp6a18 Cyp6a18 http://flybase.net/reports/FBgn0039519.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG13977, 6a18, cytochrome P450" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG13977 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0013730 ry::Cvic\Xdh Xdh http://flybase.net/reports/FBgn0013730.html engineered_fusion_gene ry::Cvic\ry 16-Dec-15 2015_12 FBgn0065870 l(2)SH0259 lethal (2) SH0259 http://flybase.net/reports/FBgn0065870.html gene l(2)SH2 0259 16-Dec-15 2015_12 "lethal,recessive" FBgn0267924 CR46205 http://flybase.net/reports/FBgn0267924.html non_protein_coding_gene lincRNA.S592 CR46205 16-Dec-15 2015_12 FBgn0262844 CG43208 http://flybase.net/reports/FBgn0262844.html protein_coding_gene MB6.chr3R.pasa.10072 CG43208 16-Dec-15 2015_12 FBgn0022217 l(2)k03609 lethal (2) k03609 http://flybase.net/reports/FBgn0022217.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265660 CR44467 http://flybase.net/reports/FBgn0265660.html non_protein_coding_gene lincRNA.328 CR44467 16-Dec-15 2015_12 FBgn0052271 CG32271 http://flybase.net/reports/FBgn0052271.html FBgn0035417 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP176, CG11532" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG32271 16-Dec-15 2015_12 viable DRSC08198 E 1.437365142 0.619467499 2.21316184 0.176839796 -0.872755352 -0.417877818 FBgn0010313 corto corto http://flybase.net/reports/FBgn0010313.html "FBgn0010917, FBgn0011464, FBgn0011465, FBgn0016125, FBgn0066000" protein_coding_gene "0003682=chromatin binding, 0042802=identical protein binding, 0005515=protein binding, 0042803=protein homodimerization activity" "0045433=male courtship behavior, veined wing generated song production, 0010468=regulation of gene expression, 0007076=mitotic chromosome condensation, 0006342=chromatin silencing, 0007474=imaginal disc-derived wing vein specification, 0060429=epithelium development" "0005700=polytene chromosome, 0035102=PRC1 complex, 0035098=ESC/E(Z) complex, 0005634=nucleus, 0005813=centrosome" "anon-WO02059370.59, ccf, CG2530, l(3)07128, l(3)neo31, Corto, Ccf, Centrosomal and chromosomal factor, l(3)neo32, 7128, centrosomal and chromosomal factor, CP-1" CG2530 16-Dec-15 2015_12 " embryonic stage | >=4hr , larval stage && pupal stage && adult stage , embryonic stage -- adult stage " "song defective,viable,female sterile,lethal,recessive,visible,dominant,partially lethal - majority die,wild-type,somatic clone,polyphasic,mitotic cell cycle defective,heat sensitive,homeotic,size defective" "macrochaeta,chorion,wing vein,ectopic,crystal cell,plasmatocyte,germline cell,male,somatic clone,imaginal disc,embryonic/larval salivary gland,embryonic/larval lymph gland,embryonic/larval brain,ring gland,gastric caecum,melanotic mass,external sensory organ,adult abdomen & macrochaeta,posterior crossvein,adult head,eye,prothoracic tarsal segment 2,sex comb,adult thorax & macrochaeta,trichogen cell,supernumerary,humerus,humeral bristle,wing,arista,haltere,genitalia,scutellar bristle,leg,scutellum,male genitalia" DRSC22988 K -0.009539051 0.451617063 0.940864345 0.644641466 2.313807191 -0.208559288 FBgn0010937 l(3)09904c lethal (3) 09904c http://flybase.net/reports/FBgn0010937.html gene "l(3)09904, unnamed" 16-Dec-15 2015_12 "female sterile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "ovariole,germline clone,egg" FBgn0003414 Streak Streak http://flybase.net/reports/FBgn0003414.html gene Sk 16-Dec-15 2015_12 "lethal,recessive,body color defective" "wing,scutellum" FBgn0003212 rc red cells http://flybase.net/reports/FBgn0003212.html gene "red-blood-cells, rbc" 16-Dec-15 2015_12 FBgn0037107 CG7166 http://flybase.net/reports/FBgn0037107.html protein_coding_gene 0005576=extracellular region CT22143 "IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set" CG7166 16-Dec-15 2015_12 WBGene00006942(wrk-1) "viable,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039731 Sas-6 Spindle assembly abnormal 6 ortholog (C. elegans) http://flybase.net/reports/FBgn0039731.html protein_coding_gene "0007052=mitotic spindle organization, 0051297=centrosome organization, 0051298=centrosome duplication, 0007099=centriole replication, 0010457=centriole-centriole cohesion" "0005813=centrosome, 0005814=centriole" "SAS-6, Sas-6, DSas-6, SAS6, DSas6, Sas6, Dsas6, dsas-6, DSAS-6, CG15524, sas-6, spindle assembly abnormal 6" CG15524 16-Dec-15 2015_12 ENSDARG00000058346(sass6) "ENSXETG00000009182(TEgg065g15.1),ENSXETG00000013202(SASS6)" ENSMUSG00000027959(Sass6) ENSG00000156876(SASS6) "viable,fertile,partially lethal - majority die,some die during pupal stage,uncoordinated" "embryonic/larval brain,embryo,centriole,centrosome,centriole | ectopicmat.ë±Tub67C.THsimVP16,centriole | ectopic,spermatid,spermatocyte" FBgn0039596 CG10000 http://flybase.net/reports/FBgn0039596.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity "0009312=oligosaccharide biosynthetic process, 0032504=multicellular organism reproduction" dppGalNAcT10 "IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain, IPR029044=Nucleotide-diphospho-sugar transferases" CG10000 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0029771 CG12730 http://flybase.net/reports/FBgn0029771.html FBgn0047186 protein_coding_gene 0016020=membrane BcDNA:RE01432 IPR008253=Marvel domain CG12730 16-Dec-15 2015_12 FBgn0027329 Tcp-1ë¦ T-cp1ë¦ http://flybase.net/reports/FBgn0027329.html "FBgn0026695, FBgn0027326, FBgn0030681" protein_coding_gene "0005524=ATP binding, 0042623=ATPase activity, coupled, 0051082=unfolded protein binding" "0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0006457=protein folding, 0090307=mitotic spindle assembly, 0031122=cytoplasmic microtubule organization, 0007099=centriole replication" "0005811=lipid particle, 0005832=chaperonin-containing T-complex, 0005875=microtubule associated complex" "Tcp-1zeta, Tcp-1-zeta, Rcd3, T-cp1zeta, Reduction in Cnn Dots 3, TCP-1zeta, l(1)G0057, CCT6, CG8231, lethal (1) G0022, l(1)G0027, l(1)G0022, Lethal (1) G0022, L(1)g0022, Q9VXQ5_DROME, TCP-1-zeta" "IPR002194=Chaperonin TCP-1, conserved site, IPR012722=T-complex protein 1, zeta subunit, IPR027410=TCP-1-like chaperonin intermediate domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1), IPR027413=GroEL-like equatorial domain, IPR027409=GroEL-like apical domain" CG8231 16-Dec-15 2015_12 ENSDARG00000021252(cct6a) YDR188W(CCT6) WBGene00000381(cct-6) ENSXETG00000010077(cct6a) "ENSMUSG00000029447(Cct6a),ENSMUSG00000020698(Cct6b)" "ENSG00000146731(CCT6A),ENSG00000132141(CCT6B)" "lethal,some die during immature adult stage,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" DRSC20095 I 1.834662738 -0.061023917 0.965202838 -0.283467013 0.137629995 -0.33206413 FBgn0028621 l(2)06655 lethal (2) 06655 http://flybase.net/reports/FBgn0028621.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085575 CG41249 http://flybase.net/reports/FBgn0085575.html FBan0041249 protein_coding_gene 16-Dec-15 2015_12 FBgn0002563 Lsp1ë_ Larval serum protein 1 ë_ http://flybase.net/reports/FBgn0002563.html protein_coding_gene 0045735=nutrient reservoir activity 0046331=lateral inhibition "0005576=extracellular region, 0005811=lipid particle, 0005616=larval serum protein complex" "Lsp1-beta, LSP1beta, Lsp1b, Larval serum protein 1[beta], DmeLSP1b, larval serum protein 1, LSP-1beta, Lsp1, LSP-1, Lsp-1b, Larval serum protein 1 beta, LSP 1, Lsp-1beta, Lsp1[beta], Larval serum protein 1beta, Lsp1beta, LSP1, larval serum protein 1beta, LSP-1 beta, CG4178" "IPR008922=Uncharacterised domain, di-copper centre, IPR013788=Hemocyanin/hexamerin, IPR005204=Hemocyanin, N-terminal, IPR005203=Hemocyanin, C-terminal, IPR000896=Hemocyanin/hexamerin middle domain, IPR014756=Immunoglobulin E-set" CG4178 16-Dec-15 2015_12 " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

"electrophoretic variant,viable,visible" "egg,chaeta" FBgn0000913 fs(1)MY18 female sterile (1) MY18 http://flybase.net/reports/FBgn0000913.html gene fs(1)MY-18 16-Dec-15 2015_12 "viable,female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "pole cell,cephalic furrow,labral segment,embryonic/larval midgut" FBgn0014063 Su(tor)3-168 Su(tor)3-168 http://flybase.net/reports/FBgn0014063.html gene 16-Dec-15 2015_12 FBgn0267077 CR45521 http://flybase.net/reports/FBgn0267077.html non_protein_coding_gene CR45521 16-Dec-15 2015_12 FBgn0011119 l(1)Q80 lethal (1) Q80 http://flybase.net/reports/FBgn0011119.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0038237 Pde6 Phosphodiesterase 6 http://flybase.net/reports/FBgn0038237.html protein_coding_gene "0047555=3',5'-cyclic-GMP phosphodiesterase activity, 0004114=3',5'-cyclic-nucleotide phosphodiesterase activity" "0032240=negative regulation of nucleobase-containing compound transport, 0007165=signal transduction, 0046068=cGMP metabolic process" "0005886=plasma membrane, 0016324=apical plasma membrane" "PDE6, DmPDE6, DmPDE5/6, CG8279" "IPR023088=3'5'-cyclic nucleotide phosphodiesterase, IPR023174=3'5'-cyclic nucleotide phosphodiesterase, conserved site, IPR003607=HD/PDEase domain, IPR002073=3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003018=GAF domain, IPR029016=GAF domain-like" CG8279 16-Dec-15 2015_12 WBGene00016328(pde-5) "viable,fertile" FBgn0061014 l(3)S026020a lethal (3) S026020a http://flybase.net/reports/FBgn0061014.html gene 0260/20 16-Dec-15 2015_12 lethal FBgn0266094 CR44831 http://flybase.net/reports/FBgn0266094.html non_protein_coding_gene CR44831 16-Dec-15 2015_12 FBgn0031914 CG5973 http://flybase.net/reports/FBgn0031914.html protein_coding_gene 0005215=transporter activity 0006810=transport 0005622=intracellular "IPR011074=CRAL/TRIO, N-terminal domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251=CRAL-TRIO lipid binding domain" CG5973 16-Dec-15 2015_12 ENSDARG00000070644(ttpal) ENSXETG00000001776(TGas020k08.1) ENSMUSG00000017679(Ttpal) ENSG00000124120(TTPAL) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034784 CG9826 http://flybase.net/reports/FBgn0034784.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG9826 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,visible" trichogen cell FBgn0039017 CG6985 http://flybase.net/reports/FBgn0039017.html protein_coding_gene IPR018838=Domain of unknown function DUF2439 CG6985 16-Dec-15 2015_12 FBgn0001372 l(1)2Ae lethal (1) 2Ae http://flybase.net/reports/FBgn0001372.html gene l(1)BA12 16-Dec-15 2015_12 lethal "eye,wing,macrochaeta,maxillary palp bristle" FBgn0265072 CR44183 http://flybase.net/reports/FBgn0265072.html non_protein_coding_gene lincRNA.125 CR44183 16-Dec-15 2015_12 FBgn0020638 Lcp65Ag1 Lcp65Ag1 http://flybase.net/reports/FBgn0020638.html FBgn0002539 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" "0040003=chitin-based cuticle development, 0008363=larval chitin-based cuticle development" "0005576=extracellular region, 0031012=extracellular matrix" "DCP8-alpha, Lcp8, L[[3]]CP8, Lcp-g1, CG10530, LCP8" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG10530 16-Dec-15 2015_12 " embryonic stage , larval stage , pupal stage | 7-13 hr " "electrophoretic variant,slow" FBgn0043031 l(2)42Cd lethal (2) 42Cd http://flybase.net/reports/FBgn0043031.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037644 CG11964 http://flybase.net/reports/FBgn0037644.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR013180=Beta-catenin-like protein 1, N-terminal, IPR011989=Armadillo-like helical" CG11964 16-Dec-15 2015_12 ENSDARG00000011958 WBGene00019711(M01E11.2) ENSXETG00000017319(ctnnbl1) ENSMUSG00000027649(Ctnnbl1) ENSG00000132792(CTNNBL1) viable FBgn0065783 l(2)SH0440 lethal (2) SH0440 http://flybase.net/reports/FBgn0065783.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069208 l(1)XPG-L lethal (1) XPG-L http://flybase.net/reports/FBgn0069208.html gene 16-Dec-15 2015_12 FBgn0260024 rey-del-mundo rey del mundo http://flybase.net/reports/FBgn0260024.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0000153 b black http://flybase.net/reports/FBgn0000153.html "FBgn0005622, FBgn0020605" protein_coding_gene "0030170=pyridoxal phosphate binding, 0004068=aspartate 1-decarboxylase activity, 0004351=glutamate decarboxylase activity" "0007632=visual behavior, 0019752=carboxylic acid metabolic process, 0006212=uracil catabolic process, 0048066=developmental pigmentation, 0019483=beta-alanine biosynthetic process" "DmGad2, Aspartate 1-decarboxylase, Oregon-R glutamate decarboxylase, BG:DS00941.5, CG7811, Aspartate-alpha-decarboxylase, Glutamic acid decarboxylase 2, GAD[[2]], black, cDNA 1, B, ADC, DGad2, Black, Gad2, anon-34Db" "IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG7811 16-Dec-15 2015_12 "ENSXETG00000012672(CSAD),ENSXETG00000014481(TGas121d14.1)" "ENSMUSG00000023044(Csad),ENSMUSG00000056880(Gadl1)" ENSG00000139631(CSAD) adult stage " dorsal medial muscle

, lamina neuropil

, mesothoracic extracoxal depressor muscle 66

" "body color defective,viable,lethal,visual behavior defective,visible,recessive,dominant" "adult cuticle,wing vein,tarsal segment,trident,puparium" FBgn0044386 Scim8 Sensitized chromosome inheritance modifier 8 http://flybase.net/reports/FBgn0044386.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0005212 l(3)ET2 lethal Elaine Tasaka 2 http://flybase.net/reports/FBgn0005212.html gene 16-Dec-15 2015_12 "lethal,cold sensitive" FBgn0266992 CR45443 http://flybase.net/reports/FBgn0266992.html non_protein_coding_gene CR45671 CR45443 16-Dec-15 2015_12 FBgn0051643 CG31643 http://flybase.net/reports/FBgn0051643.html FBgn0046218 protein_coding_gene 0004672=protein kinase activity 0006468=protein phosphorylation "CG31643PA, BcDNA:LD32258" "IPR013579=FAST kinase-like protein, subdomain 2, IPR010622=FAST kinase leucine-rich, IPR013584=RAP domain" CG31643 16-Dec-15 2015_12 ENSDARG00000056128(fastkd1) ENSXETG00000018929(TEgg089k23.1) ENSMUSG00000027086(Fastkd1) ENSG00000138399(FASTKD1) FBgn0001733 l(1)HM1 lethal (1) HM1 http://flybase.net/reports/FBgn0001733.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female sterile" FBgn0037988 CG14740 http://flybase.net/reports/FBgn0037988.html FBgn0044699 protein_coding_gene 0004108=citrate (Si)-synthase activity "0006099=tricarboxylic acid cycle, 0006101=citrate metabolic process, 0044262=cellular carbohydrate metabolic process" 0005759=mitochondrial matrix "CS, anon-WO0140519.178" "IPR002020=Citrate synthase, IPR019810=Citrate synthase active site, IPR016142=Citrate synthase-like, large alpha subdomain" CG14740 16-Dec-15 2015_12 viable FBgn0031523 CG15408 http://flybase.net/reports/FBgn0031523.html protein_coding_gene 0005353=fructose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG15408 16-Dec-15 2015_12 viable FBgn0065340 l(2)SH1835 lethal (2) SH1835 http://flybase.net/reports/FBgn0065340.html gene l(2)SH2 1835 16-Dec-15 2015_12 "lethal,recessive" FBgn0052440 CG32440 http://flybase.net/reports/FBgn0052440.html FBgn0037079 protein_coding_gene "bs36c07.y1, CG5051" CG32440 16-Dec-15 2015_12 DRSC11480 K 0.045629048 -0.627357427 -0.122462445 0.67641815 1.609674388 3.659857788 FBgn0085823 CR41617 http://flybase.net/reports/FBgn0085823.html FBan0041617 rRNA_gene CR41617 16-Dec-15 2015_12 FBgn0260602 2L1685 http://flybase.net/reports/FBgn0260602.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0010296 ng4 new glue 4 http://flybase.net/reports/FBgn0010296.html protein_coding_gene 0005198=structural molecule activity "0007127=meiosis I, 0007594=puparial adhesion" 0005576=extracellular region "ng, CG10789, ng-4, EG:96G10.2" CG10789 16-Dec-15 2015_12 " larval stage | first instar -- larval stage | second instar , pupal stage " organism

viable FBgn0065255 l(2)SH2111 lethal (2) SH2111 http://flybase.net/reports/FBgn0065255.html gene l(2)SH2 2111 16-Dec-15 2015_12 "lethal,recessive" FBgn0026089 CG14817 http://flybase.net/reports/FBgn0026089.html protein_coding_gene 0005761=mitochondrial ribosome EG:63B12.11 "IPR016576=Ribosomal protein 63, mitochondrial" CG14817 16-Dec-15 2015_12 ENSDARG00000007285(mrp63) ENSMUSG00000021967(Mrp63) ENSG00000173141(MRP63) "viable,visible" trichogen cell FBgn0037671 VhaM8.9 Vacuolar H+ ATPase M8.9 accessory subunit http://flybase.net/reports/FBgn0037671.html protein_coding_gene "0005110=frizzled-2 binding, 0005109=frizzled binding, 0004872=receptor activity" "0048104=establishment of body hair or bristle planar orientation, 0015991=ATP hydrolysis coupled proton transport, 0001737=establishment of imaginal disc-derived wing hair orientation, 0060071=Wnt signaling pathway, planar cell polarity pathway, 0035317=imaginal disc-derived wing hair organization, 0090251=protein localization involved in establishment of planar polarity, 0016197=endosomal transport, 0016055=Wnt signaling pathway" "0009986=cell surface, 0016471=vacuolar proton-transporting V-type ATPase complex, 0005886=plasma membrane, 0016021=integral component of membrane, 0045177=apical part of cell, 0005622=intracellular" "VhaM8-9, VhaPRR, dPRR, vhaM8.9, ATP6AP2, CG8444" IPR012493=Renin receptor-like CG8444 16-Dec-15 2015_12 ENSDARG00000008735(atp6ap2) ENSXETG00000015523(atp6ap2) ENSMUSG00000031007(Atp6ap2) ENSG00000182220(ATP6AP2) "lethal,visible,somatic clone,planar polarity defective,viable,partially lethal - majority die,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "wing hair,somatic clone,chaeta,macrochaeta,microchaeta,wing,wing vein,ectopic,wing margin bristle,trichogen cell" FBgn0052249 CG32249 http://flybase.net/reports/FBgn0052249.html protein_coding_gene 0004871=signal transducer activity CG32249 16-Dec-15 2015_12 "ENSXETG00000002002(),ENSXETG00000010866(),ENSXETG00000007009(),ENSXETG00000015478(),ENSXETG00000013919(),ENSXETG00000013087(),ENSXETG00000007713(),ENSXETG00000004223(),ENSXETG00000003841(),ENSXETG00000015310(),ENSXETG00000022563(),ENSXETG00000007205()" "viable,fertile" FBgn0027342 fz4 frizzled 4 http://flybase.net/reports/FBgn0027342.html "FBgn0029938, FBgn0046616, FBgn0046624" protein_coding_gene "0017147=Wnt-protein binding, 0042813=Wnt-activated receptor activity, 0004888=transmembrane signaling receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007165=signal transduction, 0016055=Wnt signaling pathway" 0016021=integral component of membrane "Fz4, Dm Fz4, DFz4, anon-WO0170980.11, anon-WO0170980.10, Dfz4, CG4626, Frizzled 4" "IPR000539=Frizzled protein, IPR015526=Frizzled/secreted frizzled-related protein, IPR020067=Frizzled domain, IPR017981=GPCR, family 2-like, IPR026551=Frizzled-4" CG4626 16-Dec-15 2015_12 "fertile,viable" FBgn0033365 CG8170 http://flybase.net/reports/FBgn0033365.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP54 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG8170 16-Dec-15 2015_12 "WBGene00006625(try-7),WBGene00006624(try-6)" FBgn0051450 mRpS18A mitochondrial ribosomal protein S18A http://flybase.net/reports/FBgn0051450.html "FBgn0037596, FBgn0064776" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "CG31450, MRP-S18-(3), mitochondrial ribosomal protein S18c, mRpS18c, BcDNA:SD13983, CG11744" IPR001648=Ribosomal protein S18 CG31450 16-Dec-15 2015_12 ENSDARG00000024465(mrps18a) ENSMUSG00000023967(Mrps18a) "viable,visible" trichogen cell FBgn0000415 dal daughterless-like http://flybase.net/reports/FBgn0000415.html gene 0001700=embryonic development via the syncytial blastoderm "daughterless-abo-like, daughterless abnormal oocyte like, daughterless abo-like" 16-Dec-15 2015_12 "lethal,maternal effect,recessive,mitotic cell cycle defective,paternal effect" nucleus | embryonic stage 4 FBgn0030693 CG8974 http://flybase.net/reports/FBgn0030693.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG8974 16-Dec-15 2015_12 ENSDARG00000032997(zgc:73070) YER116C(SLX8) WBGene00004381(rnf-5) ENSXETG00000004178(RNF185) ENSMUSG00000020448(Rnf185) ENSG00000138942(RNF185) FBgn0001020 fs(3)A11 female sterile (3) A11 http://flybase.net/reports/FBgn0001020.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0051869 CG31869 http://flybase.net/reports/FBgn0051869.html "FBgn0032300, FBgn0032302" protein_coding_gene "CG18499, CG17130" IPR001007=VWFC domain CG31869 16-Dec-15 2015_12 DRSC02674 K -0.418021603 0.210328639 -0.620167535 0.565245583 1.794511888 -0.297636765 FBgn0011587 E(top)D105 Enhancer of torpedo D105 http://flybase.net/reports/FBgn0011587.html gene 16-Dec-15 2015_12 FBgn0084617 aqz aaquetzalli http://flybase.net/reports/FBgn0084617.html gene "0035282=segmentation, 0007391=dorsal closure, 0008258=head involution" 16-Dec-15 2015_12 FBgn0011093 l(1)Q53 lethal (1) Q53 http://flybase.net/reports/FBgn0011093.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0030838 CG5445 http://flybase.net/reports/FBgn0030838.html protein_coding_gene IPR009060=UBA-like CG5445 16-Dec-15 2015_12 ENSMUSG00000056692(D17Wsu92e) ENSG00000196821(C6orf106) "viable,fertile" FBgn0032663 CG15153 http://flybase.net/reports/FBgn0032663.html protein_coding_gene IPR000859=CUB domain CG15153 16-Dec-15 2015_12 viable FBgn0264336 CR43792 http://flybase.net/reports/FBgn0264336.html non_protein_coding_gene CR43792 16-Dec-15 2015_12 FBgn0000393 cur curvoid http://flybase.net/reports/FBgn0000393.html gene 16-Dec-15 2015_12 "visible,viable,reduced" wing FBgn0263519 mir-4964 mir-4964 stem loop http://flybase.net/reports/FBgn0263519.html miRNA_gene "dme-mir-4964, CR43504" CR43504 16-Dec-15 2015_12 FBgn0036585 CG13071 http://flybase.net/reports/FBgn0036585.html protein_coding_gene CG13071 16-Dec-15 2015_12 viable FBgn0065262 l(2)SH2085 lethal (2) SH2085 http://flybase.net/reports/FBgn0065262.html gene l(2)SH2 2085 16-Dec-15 2015_12 "lethal,recessive" FBgn0065840 l(2)SH0327 lethal (2) SH0327 http://flybase.net/reports/FBgn0065840.html gene l(2)SH2 0327 16-Dec-15 2015_12 "lethal,recessive" FBgn0014309 l(3)neo65 lethal (3) neo65 http://flybase.net/reports/FBgn0014309.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040356 CG12498 http://flybase.net/reports/FBgn0040356.html FBgn0029635 protein_coding_gene 0003677=DNA binding "0006352=DNA-templated transcription, initiation, 0006368=transcription elongation from RNA polymerase II promoter, 0016570=histone modification" 0016593=Cdc73/Paf1 complex EG:BACR43E12.1 "IPR004343=Plus-3 domain, IPR018144=Plus-3 domain, subgroup, IPR031102=RNA polymerase-associated protein Rtf1" CG12498 16-Dec-15 2015_12 viable FBgn0060696 l(3)S072912 lethal (3) S072912 http://flybase.net/reports/FBgn0060696.html gene 0729/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0266059 Su(var)304 http://flybase.net/reports/FBgn0266059.html gene 304 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0004503 fs(1)ë_a8 female sterile (1) ë_a8 http://flybase.net/reports/FBgn0004503.html gene 16-Dec-15 2015_12 FBgn0050353 CG30353 http://flybase.net/reports/FBgn0050353.html protein_coding_gene 16-Dec-15 2015_12 FBgn0027616 YT521-B YT521-B http://flybase.net/reports/FBgn0027616.html protein_coding_gene 0003723=RNA binding 0016070=RNA metabolic process 0016604=nuclear body "CG12076, dYT521-B, YT521, BcDNA:GH01918" IPR007275=YTH domain CG12076 16-Dec-15 2015_12 ENSDARG00000051953(ythdc1) ENSXETG00000017960(BC081325.1) ENSMUSG00000035851(Ythdc1) ENSG00000083896(YTHDC1) "visible,viable" eye DRSC08141 I 3.166926293 -1.195285742 -0.31178111 0.010607154 1.064379101 0.825103842 FBgn0037502 wa-cup walker cup http://flybase.net/reports/FBgn0037502.html protein_coding_gene 0007140=male meiosis "walker-cup, CG10113" "IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain" CG10113 16-Dec-15 2015_12 viable FBgn0267786 CR46117 http://flybase.net/reports/FBgn0267786.html non_protein_coding_gene CR46117 16-Dec-15 2015_12 FBgn0032002 CG8353 http://flybase.net/reports/FBgn0032002.html protein_coding_gene "0004126=cytidine deaminase activity, 0008270=zinc ion binding" 0009972=cytidine deamination "IPR006262=Cytidine deaminase, homotetrameric, IPR002125=Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016193=Cytidine deaminase-like, IPR016192=APOBEC/CMP deaminase, zinc-binding" CG8353 16-Dec-15 2015_12 "ENSDARG00000038199(cda),ENSDARG00000036426(zgc:103586)" YLR245C(CDD1) "WBGene00000392(cdd-2),WBGene00000391(cdd-1)" ENSMUSG00000028755(Cda) ENSG00000158825(CDA) "viable,visible" trichogen cell FBgn0051561 Osi16 Osiris 16 http://flybase.net/reports/FBgn0051561.html FBgn0037425 protein_coding_gene 0005887=integral component of plasma membrane "Osiris, CG10314, CG31561" IPR012464=Protein of unknown function DUF1676 CG31561 16-Dec-15 2015_12 viable FBgn0065146 l(3)SH082 lethal (3) SH082 http://flybase.net/reports/FBgn0065146.html gene l(2)SH3 082 16-Dec-15 2015_12 "lethal,recessive" FBgn0043555 Su(roDOM)345 Su(roDOM)345 http://flybase.net/reports/FBgn0043555.html gene 0001745=compound eye morphogenesis unnamed 16-Dec-15 2015_12 "lethal,recessive,somatic clone" FBgn0060834 l(3)S049906c lethal (3) S049906c http://flybase.net/reports/FBgn0060834.html gene 0499/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0001918 l(2)25Be lethal (2) 25Be http://flybase.net/reports/FBgn0001918.html gene "l(2)jf14, jf14" 16-Dec-15 2015_12 lethal FBgn0044492 DTD46.5 DTD46.5 http://flybase.net/reports/FBgn0044492.html gene 16-Dec-15 2015_12 viable FBgn0265458 CR44358 http://flybase.net/reports/FBgn0265458.html non_protein_coding_gene CR44358 16-Dec-15 2015_12 FBgn0020337 anon-65Ba anon-65Ba http://flybase.net/reports/FBgn0020337.html gene "transcript x, x" 16-Dec-15 2015_12 FBgn0060975 l(3)S028929b lethal (3) S028929b http://flybase.net/reports/FBgn0060975.html gene 0289/29 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0026187 pskl pop-sickle http://flybase.net/reports/FBgn0026187.html gene 0007338=single fertilization "CG18803, popsickle" 16-Dec-15 2015_12 FBgn0037224 TwdlF TweedleF http://flybase.net/reports/FBgn0037224.html FBan0014639 protein_coding_gene 0008010=structural constituent of chitin-based larval cuticle 0040003=chitin-based cuticle development 0005578=proteinaceous extracellular matrix CG14639 IPR004145=Domain of unknown function DUF243 CG14639 16-Dec-15 2015_12 viable FBgn0085536 CG40924 http://flybase.net/reports/FBgn0085536.html FBan0040924 protein_coding_gene 16-Dec-15 2015_12 FBgn0015607 Ca-ë±2 Ca2+-channel-protein-ë±2-subunit http://flybase.net/reports/FBgn0015607.html gene 0005245=voltage-gated calcium channel activity "0005886=plasma membrane, 0005891=voltage-gated calcium channel complex" DmCa1alpha2 16-Dec-15 2015_12 FBgn0030873 CG15814 http://flybase.net/reports/FBgn0030873.html protein_coding_gene 0008270=zinc ion binding "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG15814 16-Dec-15 2015_12 "ENSDARG00000060282(im:6907121),ENSDARG00000037647(zgc:56665)" WBGene00007626(rnf-121) ENSXETG00000023935(rnf121) ENSMUSG00000070426(Rnf121) "ENSG00000137522(RNF121),ENSG00000145428(RNF175)" viable FBgn0030000 CG2260 http://flybase.net/reports/FBgn0030000.html protein_coding_gene 0022008=neurogenesis "IPR019775=WD40 repeat, conserved site, IPR012952=BING4, C-terminal domain, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG2260 16-Dec-15 2015_12 ENSDARG00000010120(wdr46) YER082C(UTP7) WBGene00009211(F28D1.1) ENSXETG00000020398(WDR46) ENSMUSG00000024312(Wdr46) "ENSG00000204221,ENSG00000007816,ENSG00000206284" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0038247 Cad88C Cadherin 88C http://flybase.net/reports/FBgn0038247.html protein_coding_gene 0005509=calcium ion binding "0007424=open tracheal system development, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0044331=cell-cell adhesion mediated by cadherin, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "Dm Cad88C, CG3389, Cad88C, DCad88C, cad88C, CT11389" "IPR020894=Cadherin conserved site, IPR002126=Cadherin, IPR015919=Cadherin-like" CG3389 16-Dec-15 2015_12 WBGene00017576(cdh-8) ENSMUSG00000034918(Cdhr2) ENSG00000074276(CDHR2) viable FBgn0021965 l(2)k10105 lethal (2) k10105 http://flybase.net/reports/FBgn0021965.html gene 16-Dec-15 2015_12 "lethal,recessive" lysosome & larval fat body | somatic clone | cell autonomous FBgn0038261 CG14856 http://flybase.net/reports/FBgn0038261.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG14856 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0024204 ol4 oocyte localisation 4 http://flybase.net/reports/FBgn0024204.html gene 16-Dec-15 2015_12 FBgn0039159 mRpS24 mitochondrial ribosomal protein S24 http://flybase.net/reports/FBgn0039159.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005763=mitochondrial small ribosomal subunit" "Mitochondrial ribosomal protein S24, MrpS24, MRP-S24, CG13608" IPR026146=28S ribosomal protein S24 CG13608 16-Dec-15 2015_12 ENSDARG00000042517(mrps24) WBGene00023487(F33D4.8) ENSXETG00000018967(MRPS24) ENSMUSG00000020477(Mrps24) ENSG00000062582(MRPS24) FBgn0267230 CR45670 http://flybase.net/reports/FBgn0267230.html non_protein_coding_gene CR45670 16-Dec-15 2015_12 FBgn0037135 CG7414 http://flybase.net/reports/FBgn0037135.html FBgn0062150 protein_coding_gene anon-WO0118547.243 "IPR011387=Translation initiation factor 2A, IPR015943=WD40/YVTN repeat-like-containing domain, IPR013979=Translation initiation factor, beta propellor-like domain" CG7414 16-Dec-15 2015_12 ENSDARG00000044479(zgc:110460) YGR054W() WBGene00008480(E04D5.1) ENSXETG00000020093(EIF2A) ENSMUSG00000027810(Eif2a) ENSG00000144895(EIF2A) "viable,fertile" FBgn0267589 CR45927 http://flybase.net/reports/FBgn0267589.html non_protein_coding_gene Mgn3598 CR45927 16-Dec-15 2015_12 FBgn0084006 CG41441 http://flybase.net/reports/FBgn0084006.html FBan0041441 protein_coding_gene 16-Dec-15 2015_12 FBgn0032032 CG17294 http://flybase.net/reports/FBgn0032032.html protein_coding_gene "0016791=phosphatase activity, 0004427=inorganic diphosphatase activity" 0006796=phosphate-containing compound metabolic process "0005634=nucleus, 0005737=cytoplasm" "Phos17294, 15010468" "IPR023215=Nitrophenylphosphatase-like domain, IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR023214=HAD-like domain, IPR006355=HAD-superfamily hydrolase, subfamily IIA, hypothetical 2" CG17294 16-Dec-15 2015_12 ENSDARG00000060196(zgc:165670) WBGene00019522(K08B12.3) ENSMUSG00000025421(Hdhd2) ENSG00000167220(HDHD2) viable FBgn0020791 prn prunus http://flybase.net/reports/FBgn0020791.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0052832 CG32832 http://flybase.net/reports/FBgn0052832.html "FBgn0045218, FBgn0045341" protein_coding_gene 0006850=mitochondrial pyruvate transport 0005743=mitochondrial inner membrane "NEST:bs21e09, bs21e09.y1, NEST:bs10d12" IPR005336=Mitochondrial pyruvate carrier CG32832 16-Dec-15 2015_12 "YHR162W(),YGR243W(FMP43)" viable FBgn0010126 l(1)M54 lethal (1) M54 http://flybase.net/reports/FBgn0010126.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003091 Pkc53E Protein C kinase 53E http://flybase.net/reports/FBgn0003091.html FBgn0034167 protein_coding_gene "0004698=calcium-dependent protein kinase C activity, 0004674=protein serine/threonine kinase activity, 0004697=protein kinase C activity, 0019992=diacylglycerol binding, 0005524=ATP binding, 0008270=zinc ion binding" "0035556=intracellular signal transduction, 2000370=positive regulation of clathrin-mediated endocytosis, 0006468=protein phosphorylation, 0035206=regulation of hemocyte proliferation" 0005886=plasma membrane "PKC-53B, Protein kinase-C 53E, Dpkc1, PKC 53E, PKC 53B, PK-C, dPKC, protein kinase C, dPKC53E(br), PKC1, Protein kinase-c1, CG6622, DPKC, pkc53e, PKC-53E, PKC, PKC53E, Pkc1" "IPR017441=Protein kinase, ATP binding site, IPR014375=Protein kinase C, alpha/beta/gamma types, IPR017892=Protein kinase, C-terminal, IPR020454=Diacylglycerol/phorbol-ester binding, IPR000719=Protein kinase domain, IPR000008=C2 domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG6622 16-Dec-15 2015_12 "ENSDARG00000008723(prkcba),ENSDARG00000022254(prkcbb)" YBL105C(PKC1) WBGene00004033(pkc-2) ENSXETG00000017294(PRKCB) "ENSMUSG00000050965(Prkca),ENSMUSG00000052889(Prkcb),ENSMUSG00000078816(Prkcc)" "ENSG00000154229(PRKCA),ENSG00000166501(PRKCB),ENSG00000126583(PRKCG)" adult stage " retina

, adult brain

, adult head

" "visible,viable,fertile,size defective,dominant" "wing vein,ectopic,wing margin,wing blade" FBgn0061169 l(1)14Bc lethal (1) 14Bc http://flybase.net/reports/FBgn0061169.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034727 mRpS29 mitochondrial ribosomal protein S29 http://flybase.net/reports/FBgn0034727.html FBgn0062242 protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0006915=apoptotic process" 0005763=mitochondrial small ribosomal subunit "CG3633, anon-WO0118547.102, MRP-S29, DAP3" "IPR019368=Ribosomal protein S23/S29, mitochondrial, IPR008092=Ribosomal protein S29, mitochondrial, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3633 16-Dec-15 2015_12 WBGene00000933(dap-3) ENSXETG00000021441(DAP3) ENSMUSG00000068921(Dap3) ENSG00000132676(DAP3) "viable,lethal,recessive" FBgn0002816 ms(2)1R male sterile (2) 1R http://flybase.net/reports/FBgn0002816.html gene 16-Dec-15 2015_12 male sterile FBgn0263499 CR43488 http://flybase.net/reports/FBgn0263499.html non_protein_coding_gene CR43488 16-Dec-15 2015_12 FBgn0264284 Su(Mir)1E3-2 http://flybase.net/reports/FBgn0264284.html gene 16-Dec-15 2015_12 "viable,female sterile" FBgn0028332 l(1)G0285 lethal (1) G0285 http://flybase.net/reports/FBgn0028332.html gene 16-Dec-15 2015_12 "female sterile,lethal,recessive" FBgn0022757 Wmc5 Wee-Mik-Complementing 5 http://flybase.net/reports/FBgn0022757.html gene WMC5 16-Dec-15 2015_12 FBgn0031760 Tsp26A Tetraspanin 26A http://flybase.net/reports/FBgn0031760.html protein_coding_gene "0007298=border follicle cell migration, 0045747=positive regulation of Notch signaling pathway" 0016021=integral component of membrane "Dm.Tsp26A, CG9093" "IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG9093 16-Dec-15 2015_12 "ENSDARG00000070456(LOC100331029),ENSDARG00000070449(zgc:101855),ENSDARG00000069466,ENSDARG00000053183,ENSDARG00000055938(tspan14)" WBGene00006638(tsp-12) "ENSXETG00000009317(TSPAN5),ENSXETG00000019632(tspan17),ENSXETG00000003514(tspan14)" "ENSMUSG00000028152(Tspan5),ENSMUSG00000025875(Tspan17),ENSMUSG00000037824(Tspan14)" "ENSG00000168785(TSPAN5),ENSG00000108219(TSPAN14)" viable "sensory mother cell,somatic clone,supernumerary" FBgn0266721 ë_Snap2 ë_ Soluble NSF attachment protein 2 http://flybase.net/reports/FBgn0266721.html "FBgn0043017, FBgn0037789" protein_coding_gene 0005483=soluble NSF attachment protein activity "0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0016082=synaptic vesicle priming, 0007269=neurotransmitter secretion" "0031201=SNARE complex, 0005737=cytoplasm" "gammaSNAP, gammaSnap2, gammaSnap-2, CG6208, SNAP-31" "IPR000744=NSF attachment protein, IPR011990=Tetratricopeptide-like helical domain" CG6208 16-Dec-15 2015_12 "ENSDARG00000006617(napgl),ENSDARG00000043012" WBGene00013345(Y59A8B.8) ENSXETG00000004052(NAPG) ENSMUSG00000024581(Napg) ENSG00000134265(NAPG) FBgn0016738 SR3-8 SR3-8 http://flybase.net/reports/FBgn0016738.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001882 l(1)YL21 lethal (1) YL21 http://flybase.net/reports/FBgn0001882.html gene 16-Dec-15 2015_12 lethal FBgn0262960 CG43271 http://flybase.net/reports/FBgn0262960.html protein_coding_gene lincRNA.174 CG43271 16-Dec-15 2015_12 FBgn0022985 qkr58E-2 quaking related 58E-2 http://flybase.net/reports/FBgn0022985.html protein_coding_gene "0003729=mRNA binding, 0003723=RNA binding" "qkr58e-2, CG5821, qrk58E-2" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG5821 16-Dec-15 2015_12 "ENSDARG00000069469(khdrbs2),ENSDARG00000070475(khdrbs1b),ENSDARG00000052856(khdrbs1a),ENSDARG00000063548" "WBGene00013325(Y57G11C.36),WBGene00019509(K07H8.9)" "ENSXETG00000004451(KHDRBS2),ENSXETG00000009227(KHDRBS3),ENSXETG00000005246(pcbp2)" "ENSMUSG00000022332(Khdrbs3),ENSMUSG00000026058(Khdrbs2),ENSMUSG00000028790(Khdrbs1)" "ENSG00000131773(KHDRBS3),ENSG00000112232(KHDRBS2),ENSG00000121774(KHDRBS1)" viable FBgn0085504 CG40626 http://flybase.net/reports/FBgn0085504.html FBan0040626 protein_coding_gene 16-Dec-15 2015_12 FBgn0033903 CG8323 http://flybase.net/reports/FBgn0033903.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG8323 16-Dec-15 2015_12 ENSDARG00000014802(si:ch211-268m12.5) YKL120W(OAC1) "ENSMUSG00000018740(Slc25a35),ENSMUSG00000040740(Slc25a34)" ENSG00000162461(SLC25A34) viable FBgn0265788 CR44577 http://flybase.net/reports/FBgn0265788.html non_protein_coding_gene CR44577 16-Dec-15 2015_12 FBgn0037720 CG8312 http://flybase.net/reports/FBgn0037720.html protein_coding_gene "IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG8312 16-Dec-15 2015_12 WBGene00009930(F52D10.2) "ENSMUSG00000046546(Fam43a),ENSMUSG00000078235(Fam43b)" "ENSG00000185112(FAM43A),ENSG00000183114(FAM43B)" FBgn0001588 l(1)carot5 lethal (1) carot5 http://flybase.net/reports/FBgn0001588.html gene 16-Dec-15 2015_12 lethal FBgn0058461 CR40461 http://flybase.net/reports/FBgn0058461.html FBan0040461 pseudogene_attribute "His2B:CG40461, CG40461" CR40461 16-Dec-15 2015_12 FBgn0259262 EP-694 http://flybase.net/reports/FBgn0259262.html gene 16-Dec-15 2015_12 "visible,planar polarity defective" wing FBgn0060748 l(3)S065208 lethal (3) S065208 http://flybase.net/reports/FBgn0060748.html gene 0652/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0035473 mge maggie http://flybase.net/reports/FBgn0035473.html "FBgn0016009, FBgn0063105" protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0006886=intracellular protein transport "0005742=mitochondrial outer membrane translocase complex, 0005739=mitochondrion" "l(3)63Fc, l(3)SH3, CG14981, BcDNA:LP07226" IPR005683=Mitochondrial import receptor subunit Tom22 CG14981 16-Dec-15 2015_12 ENSDARG00000045146(tomm22) WBGene00021133(tomm-22) ENSXETG00000006896(tomm22) ENSMUSG00000022427(Tomm22) ENSG00000100216(TOMM22) "hypoactive,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" DRSC08721 E -0.77990629 0.393829993 -1.711823052 0.078029798 -0.008625811 -0.621413854 FBgn0004165 l(2)51F lethal (2) 51F http://flybase.net/reports/FBgn0004165.html gene 16-Dec-15 2015_12 lethal FBgn0265446 CR44346 http://flybase.net/reports/FBgn0265446.html non_protein_coding_gene lincRNA.171 CR44346 16-Dec-15 2015_12 FBgn0053729 snmRNA:430:CR33729 snmRNA:430:CR33729 http://flybase.net/reports/FBgn0053729.html non_protein_coding_gene CR33729 CR33729 16-Dec-15 2015_12 FBgn0039466 CG5521 http://flybase.net/reports/FBgn0039466.html FBgn0044456 protein_coding_gene 0005096=GTPase activator activity "0090630=activation of GTPase activity, 0043547=positive regulation of GTPase activity" "0005634=nucleus, 0005829=cytosol" EP3527 "IPR000331=Rap GTPase activating protein domain, IPR016024=Armadillo-type fold" CG5521 16-Dec-15 2015_12 "ENSMUSG00000021027(Ralgapa1),ENSMUSG00000037110(Ralgapa2)" "ENSG00000174373(RALGAPA1),ENSG00000188559(RALGAPA2)" viable DRSC15828 E 0.576511726 -0.132603265 0.926451329 -2.493724775 -0.442849858 0.463312455 FBgn0065663 l(2)SH0707 lethal (2) SH0707 http://flybase.net/reports/FBgn0065663.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001006 Fs(2)X10 Female sterile (2) X10 http://flybase.net/reports/FBgn0001006.html gene 16-Dec-15 2015_12 "female sterile,dominant" egg FBgn0065070 snoRNA:291 snoRNA:291 http://flybase.net/reports/FBgn0065070.html FBgn0053638 snoRNA_gene 0005730=nucleolus "SnoR291, Dm-291, DmOr_cd7, CR33638, snoR291" CR33638 16-Dec-15 2015_12 FBgn0033129 Tsp42Eh Tetraspanin 42Eh http://flybase.net/reports/FBgn0033129.html protein_coding_gene 0016021=integral component of membrane "CG12844, Dm.Tsp42Eh, tetraspanin 42E" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG12844 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0028526 CG15293 http://flybase.net/reports/FBgn0028526.html FBgn0027904 protein_coding_gene 0005576=extracellular region "HL03474, BG:DS01759.2, CT35241" CG15293 16-Dec-15 2015_12 viable FBgn0025750 l(3)93Dm lethal (3) 93Dm http://flybase.net/reports/FBgn0025750.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0030409 CG15728 http://flybase.net/reports/FBgn0030409.html protein_coding_gene CG15728 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0001856 l(1)tsUC88 lethal (1) tsUC88 http://flybase.net/reports/FBgn0001856.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0028737 Ef1ë_ Elongation factor 1 ë_ http://flybase.net/reports/FBgn0028737.html "FBgn0025828, FBgn0027858" protein_coding_gene "0003746=translation elongation factor activity, 0005085=guanyl-nucleotide exchange factor activity, 0003747=translation release factor activity" 0006414=translational elongation "0005829=cytosol, 0005811=lipid particle, 0005853=eukaryotic translation elongation factor 1 complex" "EG:EG0003.7, Elongation factor 1beta, unnamed, Elf 1 beta, BcDNA.LD24492, Ef1beta, CG6341, 154264_at, Elongation facto 1 beta, BcDNA:LD24492, Elongation factor 1 beta" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR001326=Translation elongation factor EF1B, beta/delta chains, conserved site, IPR018940=Elongation factor 1 beta central acidic region, eukaryote, IPR014038=Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange, IPR014717=Translation elongation factor EF1B/ribosomal protein S6" CG6341 16-Dec-15 2015_12 ENSDARG00000044521(eef1b2) YAL003W(EFB1) WBGene00018846(F54H12.6) ENSXETG00000010098(EF1B_XENTR) ENSMUSG00000025967(Eef1b2) ENSG00000114942(EEF1B2) "viable,fertile,visible,lethal - all die before end of pupal stage,some die during pupal stage" "dorsocentral bristle,scutellar bristle" FBgn0027152 l(3)64Da lethal (3) 64Da http://flybase.net/reports/FBgn0027152.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0002610 M(3)62A Minute (3) 62A http://flybase.net/reports/FBgn0002610.html gene M(3)LS1 16-Dec-15 2015_12 FBgn0030756 CG9903 http://flybase.net/reports/FBgn0030756.html protein_coding_gene 0008508=bile acid:sodium symporter activity 0016020=membrane IPR002657=Bile acid:sodium symporter/arsenical resistance protein Acr3 CG9903 16-Dec-15 2015_12 ENSDARG00000030090(zgc:85947) WBGene00044650(Y71G10AR.4) "ENSXETG00000012551(SLC10A6),ENSXETG00000009830(SLC10A4)" "ENSMUSG00000032806(Slc10a3),ENSMUSG00000058921(Slc10a5)" "ENSG00000126903(SLC10A3),ENSG00000205184" viable FBgn0283466 mir-9369 mir-9369 stem loop http://flybase.net/reports/FBgn0283466.html miRNA_gene dme-mir-9369 16-Dec-15 2015_12 FBgn0044393 Scim35 Sensitized chromosome inheritance modifier 35 http://flybase.net/reports/FBgn0044393.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0047314 CR31972 http://flybase.net/reports/FBgn0047314.html FBgn0051972 non_protein_coding_gene "BcDNA:GH10270, MRE27" 16-Dec-15 2015_12 FBgn0034225 veil veil http://flybase.net/reports/FBgn0034225.html FBgn0028966 protein_coding_gene "0000166=nucleotide binding, 0008253=5'-nucleotidase activity, 0046872=metal ion binding" 0009166=nucleotide catabolic process "5'-nucleotidase-precursor, CG4827, 5' nucleotidase precursor, NT5E-1, veil" "IPR008334=5'-Nucleotidase, C-terminal, IPR006179=5'-Nucleotidase/apyrase, IPR006146=5'-Nucleotidase, conserved site, IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG4827 16-Dec-15 2015_12 ENSDARG00000071017(LOC100334175) ENSXETG00000018096(NT5E) ENSMUSG00000032420(Nt5e) ENSG00000135318(NT5E) "wing,posterior compartment" FBgn0266574 tRNA:CR45107 transfer RNA:CR45107 http://flybase.net/reports/FBgn0266574.html "FBgn0050505, FBgn0011988, FBgn0050261, FBgn0060036" tRNA_gene 0033439=ACA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "transfer RNA:thr3:47F, tRNA:thr3:47F, CR45107, tRNA:T:TGT:AE002787-a, tRNA[Thr][[3]], tRNA[[Thr]], tRNA:T3:47F, CR30505, transfer RNA:CR30505, CR30261, tRNA:CR30505, chr2R.trna83-ThrTGT, AE002787.trna24-ThrTGT" CR45107 16-Dec-15 2015_12 FBgn0030306 Spase25 Spase 25-subunit http://flybase.net/reports/FBgn0030306.html protein_coding_gene 0008233=peptidase activity 0006465=signal peptide processing "0016021=integral component of membrane, 0012505=endomembrane system, 0005787=signal peptidase complex" CG1751 IPR009582=Signal peptidase complex subunit 2 CG1751 16-Dec-15 2015_12 ENSDARG00000042823(spcs2) WBGene00012550(Y37D8A.10) ENSXETG00000025356(SPCS2_XENTR) ENSMUSG00000035227(Spcs2) ENSG00000118363(SPCS2) "lethal,recessive" FBgn0265648 CR44455 http://flybase.net/reports/FBgn0265648.html non_protein_coding_gene CR44455 16-Dec-15 2015_12 FBgn0265817 CR44606 http://flybase.net/reports/FBgn0265817.html non_protein_coding_gene lincRNA.208 CR44606 16-Dec-15 2015_12 FBgn0082684 E(ftz)2828 E(ftz)2828 http://flybase.net/reports/FBgn0082684.html gene 2828 16-Dec-15 2015_12 FBgn0025697 santa-maria scavenger receptor acting in neural tissue and majority of rhodopsin is absent http://flybase.net/reports/FBgn0025697.html FBgn0031915 protein_coding_gene 0005044=scavenger receptor activity "0006952=defense response, 0016063=rhodopsin biosynthetic process, 0035071=salivary gland cell autophagic cell death, 0043052=thermotaxis, 0048102=autophagic cell death, 0016116=carotenoid metabolic process, 0007602=phototransduction, 0007155=cell adhesion" "0016020=membrane, 0005887=integral component of plasma membrane" "CK01577, CG12789, santa maria, SANTA-MARIA, BEST:CK01577, Santa Maria, santa-maria" IPR002159=CD36 antigen CG12789 16-Dec-15 2015_12 "WBGene00013039(scav-3),WBGene00013578(scav-2)" ENSXETG00000001195(SCARB1) "viable,neurophysiology defective,thermotaxis behavior defective,auditory perception defective" FBgn0069927 CG41124 http://flybase.net/reports/FBgn0069927.html FBan0041124 protein_coding_gene 16-Dec-15 2015_12 FBgn0051030 CG31030 http://flybase.net/reports/FBgn0051030.html "FBgn0027669, FBgn0039750, FBgn0064841" protein_coding_gene "0046933=proton-transporting ATP synthase activity, rotational mechanism, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033180=proton-transporting V-type ATPase, V1 domain" "anon-EST:Posey81, CG2176, BcDNA:RH09162" "IPR008388=ATPase, V1 complex, subunit S1" CG31030 16-Dec-15 2015_12 viable FBgn0011879 tRNA:CR30233 transfer RNA:CR30233 http://flybase.net/reports/FBgn0011879.html "FBgn0050233, FBgn0060273" tRNA_gene "0033455=GCA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002787.trna46-AlaTGC, chr2R.trna29-AlaTGC, CR30233, tRNA:A:TGC:AE002787-b" CR30233 16-Dec-15 2015_12 FBgn0005378 x10 x10 http://flybase.net/reports/FBgn0005378.html gene 16-Dec-15 2015_12 FBgn0259248 C649 http://flybase.net/reports/FBgn0259248.html gene 16-Dec-15 2015_12 visible wing FBgn0032419 CG17217 http://flybase.net/reports/FBgn0032419.html protein_coding_gene CG17217 16-Dec-15 2015_12 viable FBgn0069326 X-149-3 X-149-3 http://flybase.net/reports/FBgn0069326.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0261938 mtRNApol mitochondrial RNA polymerase http://flybase.net/reports/FBgn0261938.html "FBgn0031300, FBgn0261273" protein_coding_gene "0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity" "0006351=transcription, DNA-templated" 0005739=mitochondrion "mtRNA-pol, POLRMT, mt RNA pol, CG4644" "IPR024075=DNA-directed RNA polymerase, helix hairpin domain, IPR002092=DNA-directed RNA polymerase, phage-type, IPR029262=DNA-directed RNA polymerase N-terminal domain, IPR002885=Pentatricopeptide repeat" CG4644 16-Dec-15 2015_12 ENSDARG00000061658(polrmt) YFL036W(RPO41) ENSXETG00000006545(POLRMT) ENSMUSG00000020329(Polrmt) ENSG00000099821(POLRMT) "decreased cell number,conditional,visible,size defective" "eye disc,conditional,eye" DRSC00660 E -0.362440249 0.30775138 -1.590546869 -0.336535542 0.366524768 0.361129595 FBgn0014189 Hel25E Helicase at 25E http://flybase.net/reports/FBgn0014189.html "FBgn0001929, FBgn0008648, FBgn0021910" protein_coding_gene "0003676=nucleic acid binding, 0004004=ATP-dependent RNA helicase activity, 0003724=RNA helicase activity, 0005524=ATP binding" "0006406=mRNA export from nucleus, 0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0006338=chromatin remodeling, 0007052=mitotic spindle organization" "0005634=nucleus, 0005700=polytene chromosome, 0005681=spliceosomal complex, 0005875=microtubule associated complex" "l(2)25Eb, DmRH4, hel, RNA helicase, sz, jf26, lethal(2)25Eb, helicase, WM6, l(2)gdh-12, l(2)k11511, CG7269, UAP56, Wm6, Dbp25F, l(2)gdh12, l(2)jf26, HEL, uap56, Hel" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal" CG7269 16-Dec-15 2015_12 "ENSDARG00000015111(ddx39b),ENSDARG00000006225(ddx39a),ENSDARG00000036069(bat1)" YDL084W(SUB2) WBGene00001840(hel-1) ENSXETG00000020607(ddx39) "ENSMUSG00000019432(Bat1a),ENSMUSG00000005481(Ddx39)" "ENSG00000215412,ENSG00000215425,ENSG00000198563(DDX39B),ENSG00000123136(DDX39A)" " embryonic stage | gastrula , adult stage && oogenesis stage , larval stage , embryonic stage " " mitotic domain

, follicle cell

, nurse cell

, embryonic/larval salivary gland

" "viable,fertile,lethal,recessive,enhancer of variegation,dominant,wild-type,suppressor of variegation" "adult head,adult thorax,adult abdomen,egg,germline clone,dorsal appendage,egg chamber" DRSC03342 IE 5.410190957 0.401036352 3.24716355 -3.498219858 -0.788941865 -0.750247986 FBgn0265683 CR44490 http://flybase.net/reports/FBgn0265683.html non_protein_coding_gene lincRNA.102 CR44490 16-Dec-15 2015_12 FBgn0038878 CG3301 http://flybase.net/reports/FBgn0038878.html protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process FOHSDR "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG3301 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) "viable,fertile" FBgn0029658 CG14269 http://flybase.net/reports/FBgn0029658.html protein_coding_gene CG14269 16-Dec-15 2015_12 viable FBgn0031954 CG14537 http://flybase.net/reports/FBgn0031954.html FBgn0063741 protein_coding_gene BcDNA:AT11469 CG14537 16-Dec-15 2015_12 viable FBgn0012042 AttA Attacin-A http://flybase.net/reports/FBgn0012042.html "FBgn0044580, FBgn0064916" protein_coding_gene "0042742=defense response to bacterium, 0050830=defense response to Gram-positive bacterium, 0019731=antibacterial humoral response, 0050829=defense response to Gram-negative bacterium, 0006959=humoral immune response" 0005615=extracellular space "attacin-A, Att, Attacin-A precursor, CG10146, Att-A, AttacinA, Attacin A, anon-WO0140519.5, attacinA, BcDNA:LP05763, attacin A, ATT, att, att A, attA, Attacin, Att A, Attackin, attacin" "IPR005521=Attacin, C-terminal, IPR005520=Attacin, N-terminal" CG10146 16-Dec-15 2015_12 "immune response defective,short lived,conditional,viable,partially lethal - majority die,some die during pupal stage" FBgn0052330 tRNA:CR32330 transfer RNA:CR32330 http://flybase.net/reports/FBgn0052330.html FBgn0060253 tRNA_gene 0033460=GAG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna3-GluCTC, tRNA:E:CTC:AE002584-a, AE002584.trna3-GluCTC, CR32330" CR32330 16-Dec-15 2015_12 FBgn0020628 Mst57Ca Male-specific transcript 57C http://flybase.net/reports/FBgn0020628.html gene unnamed 16-Dec-15 2015_12 FBgn0021935 l(2)k10914 lethal (2) k10914 http://flybase.net/reports/FBgn0021935.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028300 l(1)G0382 lethal (1) G0382 http://flybase.net/reports/FBgn0028300.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028275 l(1)G0430 lethal (1) G0430 http://flybase.net/reports/FBgn0028275.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033413 prel preli-like http://flybase.net/reports/FBgn0033413.html FBgn0047196 protein_coding_gene "0070584=mitochondrion morphogenesis, 0048813=dendrite morphogenesis" "0005739=mitochondrion, 0030061=mitochondrial crista" "BcDNA:LD36516, CG8806, Preli, protein of relevant evolutionary and lymphoid interest-like, Preli-like" IPR006797=PRELI/MSF1 domain CG8806 16-Dec-15 2015_12 ENSDARG00000057423(prelid1) YLR193C(UPS1) WBGene00007144(B0334.4) ENSXETG00000007235(px19) ENSMUSG00000021486(Prelid1) ENSG00000169230(PRELID1) "neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" "mitochondrion & dorsal multidendritic neuron ddaC | somatic clone,dendrite & dorsal multidendritic neuron ddaC | somatic clone,mitochondrion & dorsal multidendritic neuron ddaC | somatic cloneppk.1.9,dendrite & dorsal multidendritic neuron ddaC | somatic cloneppk.1.9,dendrite & class IV dendritic arborising neuronppk.1.9,dendrite & abdominal anterior ventral multidendritic neuron vdaappk.1.9,trichogen cell,mesothoracic tergum" FBgn0267033 mamo maternal gene required for meiosis http://flybase.net/reports/FBgn0267033.html "FBgn0030532, FBgn0052611, FBgn0030535, FBgn0030533, FBgn0030534, FBgn0085375, FBgn0052606, FBgn0263115, FBgn0264981, FBgn0265867" protein_coding_gene "0046872=metal ion binding, 0043565=sequence-specific DNA binding, 0003682=chromatin binding" "1902275=regulation of chromatin organization, 0007143=female meiotic division, 0007276=gamete generation, 0035041=sperm chromatin decondensation, 0006357=regulation of transcription from RNA polymerase II promoter" "0005737=cytoplasm, 0000228=nuclear chromosome, 0005634=nucleus" "CG11082, CG11072, CG44132, CG34346, lincRNA.990, CG45477, CG11071, CG32611, CG11075, CG32606, CR44656" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like, IPR011333=POZ domain, IPR007087=Zinc finger, C2H2" CG45477 16-Dec-15 2015_12 "ENSXETG00000021754(ZBTB34),ENSXETG00000020042(ZBTB37)" "ENSMUSG00000050240(Hic2),ENSMUSG00000043099(Hic1)" "ENSG00000213588(ZBTB9),ENSG00000204210,ENSG00000206280,ENSG00000206207,ENSG00000169155(ZBTB43)" FBgn0261793 Trf2 TATA box binding protein-related factor 2 http://flybase.net/reports/FBgn0261793.html "FBgn0026758, FBgn0026762, FBgn0030036, FBgn0026705, FBgn0040181, FBgn0040163, FBgn0026688" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0001047=core promoter binding, 0003682=chromatin binding, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" "0035075=response to ecdysone, 0006352=DNA-templated transcription, initiation, 0035277=spiracle morphogenesis, open tracheal system, 0006366=transcription from RNA polymerase II promoter, 0022008=neurogenesis, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0048812=neuron projection morphogenesis, 0035209=pupal development, 0060963=positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter, 0035071=salivary gland cell autophagic cell death" "0001673=male germ cell nucleus, 0005667=transcription factor complex, 0005700=polytene chromosome, 0001674=female germ cell nucleus, 0005669=transcription factor TFIID complex, 0005634=nucleus" "p79/TRF2, l(1)G0295, dTRF2, lethal (1) G0071, lethal (1) G0295, CG18009, dTrf2, lethal (1) G0425, dTRF2L, dTRF2S, TBP related factor 2, TLF, TATA box-binding protein related factor 2, lethal (1) G0039, TRF2, CG11195, l(1)G0425, TBP-related factor 2, TBP-like factor, l(1)G0071, trf2, l(1)G0039" "IPR015445=TATA-Box binding protein-like, IPR000814=TATA-box binding protein, IPR012295=Beta2-adaptin/TBP, C-terminal domain" CG18009 16-Dec-15 2015_12 DRSC18727 IEK -2.991479759 -0.51407372 -1.263195336 -2.010648849 0.924045504 3.369782324 FBgn0262007 CG42825 http://flybase.net/reports/FBgn0262007.html "FBan0006640, FBgn0036068, FBgn0044601" protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "GH19118, anon-WO0140519.30, CG6640" "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG42825 16-Dec-15 2015_12 viable FBgn0012030 l(2)DTS18SP lethal (2) DTS18 Suzuki & Procunier http://flybase.net/reports/FBgn0012030.html FBgn0005147 gene DTS-L18 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive" FBgn0051668 CG31668 http://flybase.net/reports/FBgn0051668.html FBgn0031396 protein_coding_gene 0005215=transporter activity "0055085=transmembrane transport, 0006810=transport" 0016020=membrane "CG10879, CG31668-PB, dSLC5A12" "IPR001734=Sodium/solute symporter, IPR019900=Sodium/solute symporter, subgroup" CG31668 16-Dec-15 2015_12 YHL016C(DUR3) WBGene00014092(ZK822.5) viable FBgn0036711 CG13727 http://flybase.net/reports/FBgn0036711.html protein_coding_gene CG13727 16-Dec-15 2015_12 viable FBgn0035122 mRpL17 mitochondrial ribosomal protein L17 http://flybase.net/reports/FBgn0035122.html FBgn0063018 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "L17, mitochondrial ribosomal protein large subunit 17, BcDNA:RE43278, mRPL17, CG13880, mrpL17" IPR000456=Ribosomal protein L17 CG13880 16-Dec-15 2015_12 WBGene00021829(Y54E10A.7) ENSXETG00000027295(Q5I032_XENTR) ENSMUSG00000030879(Mrpl17) ENSG00000158042(MRPL17) "visible,recessive,somatic clone,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,eye disc,trichogen cell" FBgn0082583 tipsy tipsy http://flybase.net/reports/FBgn0082583.html gene 0048149=behavioral response to ethanol "tps, I79" 16-Dec-15 2015_12 chemical sensitive FBgn0037762 eloF elongase F http://flybase.net/reports/FBgn0037762.html protein_coding_gene 0009922=fatty acid elongase activity "0007619=courtship behavior, 0042810=pheromone metabolic process, 0042761=very long-chain fatty acid biosynthetic process, 0030497=fatty acid elongation" 0016021=integral component of membrane "CG16905, elongase" IPR002076=ELO family CG16905 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "courtship behavior defective,mating defective,viable" FBgn0029095 aru arouser http://flybase.net/reports/FBgn0029095.html FBgn0031290 protein_coding_gene 0003735=structural constituent of ribosome "0050803=regulation of synapse structure or activity, 0042048=olfactory behavior, 0007173=epidermal growth factor receptor signaling pathway, 0006412=translation, 0007613=memory, 0045471=response to ethanol" "0045202=synapse, 0005840=ribosome" "CG4276, EPS8L3" "IPR011332=Zinc-binding ribosomal protein, IPR029071=Ubiquitin-related domain, IPR001452=SH3 domain, IPR019954=Ubiquitin conserved site, IPR013625=Tensin phosphotyrosine-binding domain, IPR000626=Ubiquitin domain, IPR002906=Ribosomal protein S27a, IPR019956=Ubiquitin" CG4276 16-Dec-15 2015_12 "ENSDARG00000058108(LOC798252),ENSDARG00000018440(zgc:56041),ENSDARG00000005704(eps8l3)" WBGene00001330(eps-8) "ENSXETG00000003193(EPS8L1),ENSXETG00000022526(EPS8)" "ENSMUSG00000015766(Eps8),ENSMUSG00000006154(Eps8l1),ENSMUSG00000025504(Eps8l2)" "ENSG00000151491(EPS8),ENSG00000177106(EPS8L2),ENSG00000131037(EPS8L1)" "smell perception defective,memory defective,chemical sensitive,lethal,chemical resistant,heat sensitive,viable,visible" "bouton,supernumerary,mesothoracic tergum" FBgn0053537 tRNA:N5:60C transfer RNA:asn5:60C http://flybase.net/reports/FBgn0053537.html "FBgn0011940, FBgn0060135" tRNA_gene "0033442=AAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:N:GTT:AE002575, CR33537, tRNA:asn5:60C, AE002575.trna5-AsnGTT, chr2R.trna49-AsnGTT" CR33537 16-Dec-15 2015_12 FBgn0259989 CG42486 http://flybase.net/reports/FBgn0259989.html FBgn0260227 protein_coding_gene CG42501 IPR002350=Kazal domain CG42486 16-Dec-15 2015_12 FBgn0038731 CG11659 http://flybase.net/reports/FBgn0038731.html protein_coding_gene "0005324=long-chain fatty acid transporter activity, 0003824=catalytic activity" 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG11659 16-Dec-15 2015_12 FBgn0034145 CG5065 http://flybase.net/reports/FBgn0034145.html protein_coding_gene "0050062=long-chain-fatty-acyl-CoA reductase activity, 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity" "0008611=ether lipid biosynthetic process, 0010025=wax biosynthetic process" "0005777=peroxisome, 0005778=peroxisomal membrane" "IPR016040=NAD(P)-binding domain, IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase" CG5065 16-Dec-15 2015_12 "ENSDARG00000006899(far1),ENSDARG00000009262(si:dkey-97m3.1)" WBGene00022200(Y71H10A.2) ENSXETG00000009049(FAR1) "ENSMUSG00000030759(Far1),ENSMUSG00000030303(Far2)" "ENSG00000197601(FAR1),ENSG00000064763(FAR2)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034990 CG11406 http://flybase.net/reports/FBgn0034990.html protein_coding_gene 0004806=triglyceride lipase activity "IPR000073=Alpha/beta hydrolase fold-1, IPR029058=Alpha/Beta hydrolase fold, IPR025483=Lipase, eukaryotic" CG11406 16-Dec-15 2015_12 YKL140W(TGL1) "viable,fertile" FBgn0001813 l(1)nc2 lethal (1) nc2 http://flybase.net/reports/FBgn0001813.html gene l(1)1625 16-Dec-15 2015_12 lethal FBgn0060800 l(3)S057310 lethal (3) S057310 http://flybase.net/reports/FBgn0060800.html gene 0573/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0004546 l(4)102CDq lethal (4) 102CDq http://flybase.net/reports/FBgn0004546.html gene "l(4)CDq, l(4)32" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030181 CG12645 http://flybase.net/reports/FBgn0030181.html protein_coding_gene IPR006629=LPS-induced tumour necrosis factor alpha factor CG12645 16-Dec-15 2015_12 lethal FBgn0083038 snoRNA:ë¬18S-525a snoRNA:ë¬18S-525a http://flybase.net/reports/FBgn0083038.html snoRNA_gene "psi18S-525a, Psi 18S-525a, CR34570" CR34570 16-Dec-15 2015_12 FBgn0039137 CG13604 http://flybase.net/reports/FBgn0039137.html protein_coding_gene 0016791=phosphatase activity 0016311=dephosphorylation 0000127=transcription factor TFIIIC complex UBASH3A "IPR009097=RNA ligase/cyclic nucleotide phosphodiesterase, IPR029033=Histidine phosphatase superfamily, IPR013078=Histidine phosphatase superfamily, clade-1, IPR001452=SH3 domain, IPR009060=UBA-like, IPR015940=Ubiquitin-associated domain" CG13604 16-Dec-15 2015_12 ENSDARG00000061243(LOC558545) ENSXETG00000003900(UBASH3B) "ENSMUSG00000032020(Ubash3b),ENSMUSG00000042345(Ubash3a)" "ENSG00000154127(UBASH3B),ENSG00000160185(UBASH3A)" "viable,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0000680 flrdC flight reduced C http://flybase.net/reports/FBgn0000680.html gene 0007629=flight behavior 16-Dec-15 2015_12 "courtship behavior defective,jumping defective,visible,flight defective" wing FBgn0083141 Spn28B Serpin 28B http://flybase.net/reports/FBgn0083141.html FBgn0031924 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis, 0032504=multicellular organism reproduction, 0010951=negative regulation of endopeptidase activity" 0005615=extracellular space "Serine protease inhibitor 7, Spn28B, CG6717, Spn7" "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG6717 16-Dec-15 2015_12 "ENSDARG00000070396(serpinb1l2),ENSDARG00000055416(serpinb1),ENSDARG00000055431,ENSDARG00000057263(zgc:173729),ENSDARG00000059873,ENSDARG00000039849,ENSDARG00000014556" "ENSXETG00000027588(serpinb6),ENSXETG00000027590(BC087996.1),ENSXETG00000025592()" "ENSG00000206073(SERPINB4),ENSG00000057149(SERPINB3),ENSG00000197641(SERPINB13),ENSG00000166634(SERPINB12),ENSG00000166396(SERPINB7),ENSG00000117601(SERPINC1)" viable FBgn0065440 l(2)SH1459 lethal (2) SH1459 http://flybase.net/reports/FBgn0065440.html gene l(2)SH2 1459 16-Dec-15 2015_12 "lethal,recessive" FBgn0016634 E(gl)3B Enhancer of glass 3B http://flybase.net/reports/FBgn0016634.html gene 16-Dec-15 2015_12 "lethal,recessive" rhabdomere FBgn0002857 Mst47A Male-specific RNA 47A http://flybase.net/reports/FBgn0002857.html gene "mst-325, mst325" 16-Dec-15 2015_12 FBgn0051391 CG31391 http://flybase.net/reports/FBgn0051391.html "FBgn0037823, FBgn0065026" protein_coding_gene 0019902=phosphatase binding 0010923=negative regulation of phosphatase activity "BcDNA:AT04406, CG6471" IPR026142=Protein phosphatase 1 regulatory subunit 36 CG31391 16-Dec-15 2015_12 ENSMUSG00000052221(Gm70) ENSG00000165807(C14orf50) "viable,fertile" FBgn0051616 His-ë¬:CR31616 His-ë¬:CR31616 http://flybase.net/reports/FBgn0051616.html pseudogene_attribute "bs28b08.y1, CR31616" CR31616 16-Dec-15 2015_12 FBgn0267178 CR45618 http://flybase.net/reports/FBgn0267178.html non_protein_coding_gene CR45618 16-Dec-15 2015_12 FBgn0065852 l(2)SH0303 lethal (2) SH0303 http://flybase.net/reports/FBgn0065852.html gene l(2)SH2 0303 16-Dec-15 2015_12 "lethal,recessive" FBgn0005308 ms(1)RD7 male sterile (1) RD7 http://flybase.net/reports/FBgn0005308.html gene ms(1)RD-7 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective" "meiosis I & spindle | male,meiosis II & spindle | male,meiotic anaphase I & nuclear chromosome | male,spermatid & nucleus,meiotic cell cycle & centriole | male,spermatid,meiosis & nuclear chromosome" FBgn0085385 CG34356 http://flybase.net/reports/FBgn0085385.html "FBgn0036061, FBgn0036060" protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity" 0006468=protein phosphorylation "CG14163, CG12524" "IPR011989=Armadillo-like helical, IPR011009=Protein kinase-like domain, IPR016024=Armadillo-type fold, IPR000719=Protein kinase domain" CG34356 16-Dec-15 2015_12 YGL083W(SCY1) WBGene00022635(ZC581.9) "visible,body color defective,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum FBgn0060481 l(3)S110915 lethal (3) S110915 http://flybase.net/reports/FBgn0060481.html gene 1109/15 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0046677 anon-38C.18 anon-38C.18 http://flybase.net/reports/FBgn0046677.html gene 38C.18 16-Dec-15 2015_12 FBgn0037915 CG6790 http://flybase.net/reports/FBgn0037915.html "FBgn0044690, FBgn0046013" protein_coding_gene 0016740=transferase activity 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane "NEST:bs22e02, anon-WO0140519.186" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017852=GPI ethanolamine phosphate transferase 1, C-terminal, IPR007070=GPI ethanolamine phosphate transferase 1, IPR017850=Alkaline-phosphatase-like, core domain" CG6790 16-Dec-15 2015_12 viable FBgn0037880 CG17726 http://flybase.net/reports/FBgn0037880.html protein_coding_gene 0032981=mitochondrial respiratory chain complex I assembly 0005739=mitochondrion "IPR003788=Putative S-adenosyl-L-methionine-dependent methyltransferase MidA, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG17726 16-Dec-15 2015_12 ENSDARG00000033134(zgc:153989) WBGene00014227(ZK1128.1) ENSXETG00000000653(C2orf56) ENSMUSG00000024082(2410091C18Rik) ENSG00000003509(C2orf56) viable FBgn0020220 Crp22 Chromatin decondensation protein 22 http://flybase.net/reports/FBgn0020220.html gene "p22, unnamed" 16-Dec-15 2015_12 FBgn0002205 l(3)67BDc lethal (3) 67BDc http://flybase.net/reports/FBgn0002205.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal" FBgn0060706 l(3)S070717 lethal (3) S070717 http://flybase.net/reports/FBgn0060706.html gene 0707/17 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0038158 CG14370 http://flybase.net/reports/FBgn0038158.html protein_coding_gene CG14370 16-Dec-15 2015_12 viable FBgn0261882 l(2)35Bc lethal (2) 35Bc http://flybase.net/reports/FBgn0261882.html "FBgn0001973, FBgn0028925" protein_coding_gene "0000287=magnesium ion binding, 0008193=tRNA guanylyltransferase activity" "0022008=neurogenesis, 0008033=tRNA processing, 0006400=tRNA modification" 0005737=cytoplasm "l(2)br13, l(2)k08808, lethal group C1, l(2)br11, br4, lethal 13 in the black-reduced region, lethal 11 in the black-reduced region, C1, BG:DS00929.4, l(2)br4, CG4103, lethal 4 in the black-reduced region, l(2)br" "IPR024956=tRNAHis guanylyltransferase catalytic domain, IPR007537=tRNAHis guanylyltransferase Thg1, IPR025845=Thg1 C-terminal domain" CG4103 16-Dec-15 2015_12 ENSDARG00000038360(zgc:101609) YGR024C(THG1) ENSXETG00000007902(THG1L) ENSMUSG00000011254(Thg1l) ENSG00000113272(THG1L) FBgn0034513 CG13423 http://flybase.net/reports/FBgn0034513.html protein_coding_gene 0004197=cysteine-type endopeptidase activity 0006508=proteolysis "IPR004134=Peptidase C1B, bleomycin hydrolase" CG13423 16-Dec-15 2015_12 viable FBgn0029822 CG12236 http://flybase.net/reports/FBgn0029822.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like" CG12236 16-Dec-15 2015_12 "ENSDARG00000061110(zbtb44),ENSDARG00000070864(bcl6a)" "YPR015C(),YPR013C()" ENSXETG00000000723(NACC2) ENSG00000160877(NACC1) FBgn0261245 sing singles bar http://flybase.net/reports/FBgn0261245.html "FBgn0022723, FBgn0030771" protein_coding_gene "0007527=adult somatic muscle development, 0007520=myoblast fusion" 0016020=membrane "singles-bar, CG13011" IPR008253=Marvel domain CG13011 16-Dec-15 2015_12 FBgn0037747 CG8481 http://flybase.net/reports/FBgn0037747.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008080=N-acetyltransferase activity" "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG8481 16-Dec-15 2015_12 WBGene00016983(C56G2.15) ENSXETG00000007327(NAT6) "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0062698 EP1139 EP1139 http://flybase.net/reports/FBgn0062698.html gene EP(2)1139 16-Dec-15 2015_12 FBgn0067876 Mod(Prat:bw)3-10 Mod(Prat:bw)3-10 http://flybase.net/reports/FBgn0067876.html gene Mod-3-10 16-Dec-15 2015_12 suppressor of variegation FBgn0038833 CG15696 http://flybase.net/reports/FBgn0038833.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG15696 16-Dec-15 2015_12 "ENSDARG00000015674(msxc),ENSDARG00000008886(msxb)" viable FBgn0024359 ES1-1 Enhancer of GMR-sina 1-1 http://flybase.net/reports/FBgn0024359.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 "eye photoreceptor cell,somatic clone,ommatidium" FBgn0050436 CG30436 http://flybase.net/reports/FBgn0050436.html protein_coding_gene 16-Dec-15 2015_12 FBgn0250833 CG34461 http://flybase.net/reports/FBgn0250833.html "FBgn0085490, FBgn0035874, FBgn0066971" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Cpr66Ca, DmelCpr66Ca, CG7072, anon-SAGE:Wang-027" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG34461 16-Dec-15 2015_12 viable DRSC10767 E 0.104629907 0.610326479 2.001534317 0.405183842 -0.419032544 -1.26810773 FBgn0265107 CR44209 http://flybase.net/reports/FBgn0265107.html non_protein_coding_gene CR44209 16-Dec-15 2015_12 FBgn0005121 l(1)S9 lethal (1) S9 http://flybase.net/reports/FBgn0005121.html gene 16-Dec-15 2015_12 "lethal,polyphasic" "embryo,anterior,cleavage nucleus" FBgn0264567 CR43939 http://flybase.net/reports/FBgn0264567.html non_protein_coding_gene CR43939 16-Dec-15 2015_12 FBgn0005529 l(2)52ACf lethal (2) 52ACf http://flybase.net/reports/FBgn0005529.html gene unnamed 16-Dec-15 2015_12 FBgn0264863 CR44054 http://flybase.net/reports/FBgn0264863.html non_protein_coding_gene CR44054 16-Dec-15 2015_12 FBgn0061163 l(1)6C-157 lethal (1) 6C-157 http://flybase.net/reports/FBgn0061163.html gene 6C-157 16-Dec-15 2015_12 "lethal,recessive" FBgn0033258 CG8712 http://flybase.net/reports/FBgn0033258.html protein_coding_gene CG8712 16-Dec-15 2015_12 "viable,fertile" FBgn0002314 l(3)85Ae lethal (3) 85Ae http://flybase.net/reports/FBgn0002314.html gene L5 16-Dec-15 2015_12 lethal FBgn0037942 CG14721 http://flybase.net/reports/FBgn0037942.html protein_coding_gene "0005524=ATP binding, 0004788=thiamine diphosphokinase activity, 0030975=thiamine binding" "0006772=thiamine metabolic process, 0009229=thiamine diphosphate biosynthetic process" "IPR007371=Thiamin pyrophosphokinase, catalytic domain, IPR006282=Thiamin pyrophosphokinase, IPR007373=Thiamin pyrophosphokinase, vitamin B1-binding domain" CG14721 16-Dec-15 2015_12 ENSDARG00000038040(zgc:101685) YOR143C(THI80) WBGene00014027(tpk-1) ENSXETG00000015845(tpk1) ENSMUSG00000029735(Tpk1) ENSG00000196511(TPK1) "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0266169 CR44875 http://flybase.net/reports/FBgn0266169.html non_protein_coding_gene CR44875 16-Dec-15 2015_12 FBgn0025754 l(3)93DFh lethal (3) 93DFh http://flybase.net/reports/FBgn0025754.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0052792 ppk8 pickpocket 8 http://flybase.net/reports/FBgn0052792.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "CG32792, ppk29, ppk8, pickpocket 8" "IPR001873=Na+ channel, amiloride-sensitive" CG32792 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" WBGene00022815(asic-1) "ENSXETG00000001026(),ENSXETG00000018954(scnn1a)" ENSMUSG00000030340(Scnn1a) "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" "viable,touch sensitivity defective,fertile" FBgn0002488 l(3)SG48 lethal (3) SG48 http://flybase.net/reports/FBgn0002488.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0060692 l(3)S073403 lethal (3) S073403 http://flybase.net/reports/FBgn0060692.html gene 0734/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0037581 CG7352 http://flybase.net/reports/FBgn0037581.html protein_coding_gene CG7352 16-Dec-15 2015_12 viable FBgn0041753 hedera hedera http://flybase.net/reports/FBgn0041753.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0085517 CG40793 http://flybase.net/reports/FBgn0085517.html FBan0040793 protein_coding_gene 16-Dec-15 2015_12 FBgn0265927 CR44716 http://flybase.net/reports/FBgn0265927.html non_protein_coding_gene lincRNA.504 CR44716 16-Dec-15 2015_12 FBgn0024704 anon-86Ca anon-86Ca http://flybase.net/reports/FBgn0024704.html gene Group 1 16-Dec-15 2015_12 FBgn0041610 abd-A::Ubx abd-A::Ubx http://flybase.net/reports/FBgn0041610.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0053203 CG33203 http://flybase.net/reports/FBgn0053203.html "FBgn0039608, FBgn0039610, FBgn0039615, FBgn0051046" protein_coding_gene 0046331=lateral inhibition 0016021=integral component of membrane "CG14524, CG31046, CG14525, CG14522" IPR004254=AdipoR/Haemolysin-III-related CG33203 16-Dec-15 2015_12 ENSXETG00000018364(PAQR4) ENSMUSG00000023909(Paqr4) ENSG00000162073(PAQR4) "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0037953 CG14727 http://flybase.net/reports/FBgn0037953.html protein_coding_gene 16-Dec-15 2015_12 FBgn0259213 CG42313 http://flybase.net/reports/FBgn0259213.html "FBgn0053515, FBgn0028890, FBgn0028914, FBgn0032556, FBgn0032557, FBtr0080678, FBpp0080240, FBtr0080679, FBpp0080241, FBgn0032555" protein_coding_gene "CG15275, BG:SD01219.3, CG15277, 42313, CT35222, cg15277, BG:DS01219.3, BG:DS03144.1, CG33515, CG15276" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set" CG42313 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" DRSC02480 E 0.750418526 0.380029236 1.165203855 2.366792169 -0.257905605 0.812918767 FBgn0262812 CG43183 http://flybase.net/reports/FBgn0262812.html protein_coding_gene "DMG4-MB6.chr2R.8.009, DMG4-MB6.chr2R.8.009-MIP07212, lincRNA.270" CG43183 16-Dec-15 2015_12 FBgn0262433 mir-210 mir-210 stem loop http://flybase.net/reports/FBgn0262433.html "FBgn0067724, FBgn0262284" miRNA_gene "miR-210, CR42991, mir-210, CR33578, dme-mir-210, dme-miR-210" CR42991 16-Dec-15 2015_12 "visible,lethal,partially lethal - majority die" "wing,wing vein,wing margin,1st posterior cell" FBgn0029807 CG3108 http://flybase.net/reports/FBgn0029807.html protein_coding_gene "0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" 0006508=proteolysis "IPR000834=Peptidase M14, carboxypeptidase A, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide" CG3108 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036849 CG14079 http://flybase.net/reports/FBgn0036849.html protein_coding_gene CG14079 16-Dec-15 2015_12 ENSDARG00000021115(spata6) viable FBgn0003224 reduced-eyes reduced eyes http://flybase.net/reports/FBgn0003224.html gene re 16-Dec-15 2015_12 sterile ommatidium FBgn0032428 CG6405 http://flybase.net/reports/FBgn0032428.html protein_coding_gene 0005515=protein binding 0050709=negative regulation of protein secretion "0005634=nucleus, 0005737=cytoplasm" IPR009602=FAM92 protein CG6405 16-Dec-15 2015_12 ENSDARG00000004436(fam92a1) "ENSXETG00000014666(),ENSXETG00000017416(FAM92B)" "ENSMUSG00000028218(Fam92a),ENSMUSG00000042269(Fam92b)" "ENSG00000157021,ENSG00000188343(FAM92A1),ENSG00000153789(FAM92B)" viable embryonic/larval salivary gland FBgn0039261 CG6422 http://flybase.net/reports/FBgn0039261.html protein_coding_gene IPR007275=YTH domain CG6422 16-Dec-15 2015_12 "ENSDARG00000014498(yth2),ENSDARG00000057939(ythdf3),ENSDARG00000016447(ythdf1)" "ENSXETG00000020636(YTHDF2),ENSXETG00000021659(YTHDF3),ENSXETG00000027086(Q6P1V5_XENTR)" "ENSMUSG00000040025(Ythdf2),ENSMUSG00000038848(Ythdf1),ENSMUSG00000047213(Ythdf3)" "ENSG00000198492(YTHDF2),ENSG00000185728,ENSG00000149658(YTHDF1)" viable FBgn0261261 plx pollux http://flybase.net/reports/FBgn0261261.html "FBgn0004879, FBgn0037366, FBgn0083958" protein_coding_gene "0005096=GTPase activator activity, 0005178=integrin binding" "0033627=cell adhesion mediated by integrin, 0043087=regulation of GTPase activity" 0009986=cell surface "CG1093, CG42612, CG14674, Pollux, CG34122" "IPR000195=Rab-GTPase-TBC domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006020=PTB/PI domain, IPR021785=Protein of unknown function DUF3350" CG42612 16-Dec-15 2015_12 ENSDARG00000062081(tbc1d1) ENSXETG00000004713(TBC1D4) "ENSMUSG00000029174(Tbc1d1),ENSMUSG00000033083(Tbc1d4)" "ENSG00000136111(TBC1D4),ENSG00000065882(TBC1D1)" " adult stage , embryonic stage -- adult stage " organism

" embryonic stage | stage >=15 , embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 13-17 , embryonic stage | stage 5 , embryonic stage | stage >=13 " " embryonic/larval trachea

, neuron

, endocuticle

, neuron

, cell body

,

, longitudinal connective

" FBgn0038189 Art6 Arginine methyltransferase 6 http://flybase.net/reports/FBgn0038189.html protein_coding_gene 0016274=protein-arginine N-methyltransferase activity 0018216=peptidyl-arginine methylation 0005634=nucleus "DART6, CG9927" "IPR025799=Protein arginine N-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG9927 16-Dec-15 2015_12 viable FBgn0261844 pre-mod(mdg4)-V http://flybase.net/reports/FBgn0261844.html protein_coding_gene CG42776 "IPR007588=Zinc finger, FLYWCH-type" CG42776 16-Dec-15 2015_12 FBgn0038810 Srp72 Signal recognition particle protein 72 http://flybase.net/reports/FBgn0038810.html protein_coding_gene 0008312=7S RNA binding "0006614=SRP-dependent cotranslational protein targeting to membrane, 0033227=dsRNA transport" "0005786=signal recognition particle, endoplasmic reticulum targeting" "Srp72, CG5434" "IPR026270=Signal recognition particle, SRP72 subunit, IPR011990=Tetratricopeptide-like helical domain, IPR013699=Signal recognition particle, SRP72 subunit, RNA-binding, IPR019734=Tetratricopeptide repeat" CG5434 16-Dec-15 2015_12 ENSDARG00000014139(srp72) YPL210C(SRP72) WBGene00017245(F08D12.1) ENSXETG00000010205(srp72) ENSMUSG00000036323(Srp72) ENSG00000174780(SRP72) lethal FBgn0030027 CG1632 http://flybase.net/reports/FBgn0030027.html protein_coding_gene "0005041=low-density lipoprotein receptor activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis SPH198 "IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000082=SEA domain, IPR017343=Uncharacterised conserved protein UCP037987, IPR020067=Frizzled domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG1632 16-Dec-15 2015_12 ENSDARG00000044655(st14b) ENSMUSG00000005220(Corin) ENSG00000145244(CORIN) viable FBgn0035689 CG7376 http://flybase.net/reports/FBgn0035689.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding, 0005524=ATP binding" "0022008=neurogenesis, 0000209=protein polyubiquitination" SHPRH "IPR001841=Zinc finger, RING-type, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain, IPR001965=Zinc finger, PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013026=Tetratricopeptide repeat-containing domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR019734=Tetratricopeptide repeat" CG7376 16-Dec-15 2015_12 YLR247C(IRC20) WBGene00020235(T05A12.4) ENSMUSG00000039282(Shprh) ENSG00000146414(SHPRH) "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0028518 CG18480 http://flybase.net/reports/FBgn0028518.html "FBgn0027846, FBgn0032567" protein_coding_gene "BG:DS07108.4, BcDNA:LP11031, CT42128" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG18480 16-Dec-15 2015_12 "ENSDARG00000055132,ENSDARG00000060459(LOC797812),ENSDARG00000039500" "ENSXETG00000007822(LRFN2),ENSXETG00000021492(LRFN5),ENSXETG00000009607(LRFN3),ENSXETG00000005309(LRFN1),ENSXETG00000005310()" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0035335 mRpL23 mitochondrial ribosomal protein L23 http://flybase.net/reports/FBgn0035335.html FBgn0047103 protein_coding_gene "0000166=nucleotide binding, 0003735=structural constituent of ribosome" 0006412=translation 0005762=mitochondrial large ribosomal subunit "L23, CG1320, BcDNA:RE49852" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR012678=Ribosomal protein L23/L15e core domain, IPR013025=Ribosomal protein L25/L23" CG1320 16-Dec-15 2015_12 ENSDARG00000045696(mrpl23) WBGene00020348(T08B2.8) ENSXETG00000014017(mrpl23) "ENSMUSG00000075279(Mrpl23-ps1),ENSMUSG00000037772(Mrpl23)" ENSG00000214026(MRPL23) "viable,visible" trichogen cell FBgn0260089 2L1693 http://flybase.net/reports/FBgn0260089.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0038931 CG13407 http://flybase.net/reports/FBgn0038931.html protein_coding_gene CG13407 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0011885 tRNA:I:49Fe transfer RNA:ile:49Fe http://flybase.net/reports/FBgn0011885.html "FBgn0003788, FBgn0050247, FBgn0060196" tRNA_gene "0033433=AUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "ile-e, chr2R.trna22-IleAAT, tRNA:ile:49Fe, CR30247, AE002787.trna40-IleAAT, tRNA:I:AAT:AE002787-f, tRNA[Ile]" CR30247 16-Dec-15 2015_12 FBgn0060879 l(3)S045311 lethal (3) S045311 http://flybase.net/reports/FBgn0060879.html gene 0453/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0082639 R705.1 R705.1 http://flybase.net/reports/FBgn0082639.html gene 16-Dec-15 2015_12 crystal cell FBgn0031942 CG7203 http://flybase.net/reports/FBgn0031942.html protein_coding_gene CG7203 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0029785 RpL35 Ribosomal protein L35 http://flybase.net/reports/FBgn0029785.html "FBgn0025262, FBgn0026281, FBgn0063066" protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0051298=centrosome duplication, 0000022=mitotic spindle elongation" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "anon-EST:fe1C12, Rp L35, CG4111, RpL35e, BcDNA:RE09547, unnamed, anon-fast-evolving-1C12, anon-EST:Posey157" "IPR001854=Ribosomal protein L29, IPR018254=Ribosomal protein L29, conserved site" CG4111 16-Dec-15 2015_12 ENSDARG00000018334(rpl35) "YDL191W(RPL35A),YDL136W(RPL35B)" WBGene00004449(rpl-35) ENSXETG00000016843(BC059774.1) "ENSMUSG00000078193(Gm2000),ENSMUSG00000062997(Rpl35),ENSMUSG00000069439(Gm10269)" ENSG00000136942(RPL35) lethal DRSC18347 IEK -2.665714012 -0.782623179 -0.015926833 -2.818422194 -0.019687911 2.960935687 FBgn0051544 CG31544 http://flybase.net/reports/FBgn0051544.html protein_coding_gene IPR002172=Low-density lipoprotein (LDL) receptor class A repeat CG31544 16-Dec-15 2015_12 viable FBgn0261811 pico pico http://flybase.net/reports/FBgn0261811.html "FBgn0082586, FBgn0031079, FBgn0047191" protein_coding_gene 0008157=protein phosphatase 1 binding "0051781=positive regulation of cell division, 0045927=positive regulation of growth, 0007444=imaginal disc development, 0048639=positive regulation of developmental growth, 0008361=regulation of cell size, 0046331=lateral inhibition, 0007165=signal transduction, 0007015=actin filament organization" 0032433=filopodium tip "BcDNA:LP01106, john glenn, CG11940, Pico, jog, John Glenn" "IPR029071=Ubiquitin-related domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000159=Ras-associating (RA) domain, IPR001849=Pleckstrin homology domain" CG11940 16-Dec-15 2015_12 ENSDARG00000061732(si:dkey-1h24.3) WBGene00003243(mig-10) "ENSG00000173166(RAPH1),ENSG00000077420(APBB1IP)" FBgn0022330 gtw gtw http://flybase.net/reports/FBgn0022330.html gene 16-Dec-15 2015_12 visible "ommatidium,lamina" FBgn0016032 lbm late bloomer http://flybase.net/reports/FBgn0016032.html protein_coding_gene 0007416=synapse assembly "0005576=extracellular region, 0016021=integral component of membrane" "Dm.Tsp42Em, LBM, Late bloomer, tetraspanin 42E, Lbm, lbl, CG2374, latebloomer, Late Bloomer, Ibm" "IPR008952=Tetraspanin, EC2 domain, IPR018499=Tetraspanin/Peripherin" CG2374 16-Dec-15 2015_12 embryonic stage | stage 14 " RP neuron

, U neuron

, VUM neuron

, aCC neuron

" embryonic stage | stage 16 motor neuron

"neuroanatomy defective,viable" "synapse,RP3 motor neuron,RP3 neuron & synapse,growth cone,presynaptic ribbon" FBgn0039594 CG9990 http://flybase.net/reports/FBgn0039594.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0006810=transport "0043190=ATP-binding cassette (ABC) transporter complex, 0005886=plasma membrane" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR000412=ABC-2 transporter, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR013525=ABC-2 type transporter" CG9990 16-Dec-15 2015_12 ENSDARG00000071341 lethal FBgn0016905 l(3)X1 lethal (3) X1 http://flybase.net/reports/FBgn0016905.html gene X1 16-Dec-15 2015_12 FBgn0265449 CR44349 http://flybase.net/reports/FBgn0265449.html non_protein_coding_gene CR44349 16-Dec-15 2015_12 FBgn0038056 CG5961 http://flybase.net/reports/FBgn0038056.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO9 "IPR007330=MIT, IPR001810=F-box domain, IPR013026=Tetratricopeptide repeat-containing domain" CG5961 16-Dec-15 2015_12 ENSDARG00000011055(fbxo9) YLR097C(HRT3) ENSXETG00000015980(fbxo9) ENSMUSG00000001366(Fbxo9) ENSG00000112146(FBXO9) viable FBgn0029665 CG14270 http://flybase.net/reports/FBgn0029665.html protein_coding_gene IPR019322=Protein of unknown function DUF2366 CG14270 16-Dec-15 2015_12 ENSDARG00000037909(zgc:110046) WBGene00011017(R04F11.5) ENSXETG00000024867(BC084188.1) ENSMUSG00000048429(1810026J23Rik) ENSG00000142444(C19orf52) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0042711 Hex-t1 Hex-t1 http://flybase.net/reports/FBgn0042711.html "FBgn0029168, FBgn0039426, FBgn0053102" protein_coding_gene "0004396=hexokinase activity, 0008865=fructokinase activity, 0005524=ATP binding, 0004340=glucokinase activity, 0005536=glucose binding, 0019158=mannokinase activity" "0006096=glycolytic process, 0046835=carbohydrate phosphorylation, 0001678=cellular glucose homeostasis" 0005829=cytosol "DHK-453, CG54430, Hex, Hexokinase, CG33102, HEX-t1, hexokinase, Hexokinase-t1, HK, CG5443" "IPR022672=Hexokinase, N-terminal, IPR022673=Hexokinase, C-terminal, IPR001312=Hexokinase" CG33102 16-Dec-15 2015_12 "YFR053C(HXK1),YGL253W(HXK2)" viable FBgn0011186 l(1)294-44 lethal (1) 294-44 http://flybase.net/reports/FBgn0011186.html FBgn0010200 gene 294-44 16-Dec-15 2015_12 "lethal,recessive" FBgn0053385 5SrRNA:CR33385 5SrRNA:CR33385 http://flybase.net/reports/FBgn0053385.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33385 CR33385 16-Dec-15 2015_12 FBgn0030452 MFS10 Major Facilitator Superfamily Transporter 10 http://flybase.net/reports/FBgn0030452.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "AA202479, CG4330" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG4330 16-Dec-15 2015_12 "ENSDARG00000055190(slc17a5),ENSDARG00000039995" "YOR378W(),YML116W(ATR1),YMR279C()" ENSMUSG00000049624(Slc17a5) "viable,fertile" FBgn0036263 thoc6 thoc6 http://flybase.net/reports/FBgn0036263.html protein_coding_gene 0006406=mRNA export from nucleus 0000347=THO complex "CG5632, Thoc6, THOC6" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG5632 16-Dec-15 2015_12 ENSDARG00000037966(thoc6) ENSXETG00000011373(THOC6) ENSMUSG00000041319(Thoc6) ENSG00000131652(THOC6) "viable,fertile" FBgn0263651 CR43642 http://flybase.net/reports/FBgn0263651.html non_protein_coding_gene CR43642 16-Dec-15 2015_12 FBgn0017440 anon-21Cc anon-21Cc http://flybase.net/reports/FBgn0017440.html gene 16-Dec-15 2015_12 FBgn0028600 l(2)W7 lethal (2) W7 http://flybase.net/reports/FBgn0028600.html gene l(2R)W7 16-Dec-15 2015_12 "lethal,recessive" FBgn0067649 sd-6 sd-6 http://flybase.net/reports/FBgn0067649.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 6 16-Dec-15 2015_12 "viable,neurophysiology defective,somatic clone,phototaxis defective" FBgn0005689 Nc18A Neural conserved at 18A http://flybase.net/reports/FBgn0005689.html gene NC18A 16-Dec-15 2015_12 FBgn0017421 anon-75Ea anon-75Ea http://flybase.net/reports/FBgn0017421.html gene 16-Dec-15 2015_12 FBgn0030296 CG15196 http://flybase.net/reports/FBgn0030296.html protein_coding_gene CG15196 16-Dec-15 2015_12 "viable,fertile" FBgn0036979 CG13247 http://flybase.net/reports/FBgn0036979.html protein_coding_gene CG13247 16-Dec-15 2015_12 DRSC11695 K -0.527541286 -0.020453409 -0.107203607 0.548503251 -2.182188963 -1.418069493 FBgn0277429 l(3)psg24 http://flybase.net/reports/FBgn0277429.html gene psg24 16-Dec-15 2015_12 FBgn0001274 Is Isis http://flybase.net/reports/FBgn0001274.html gene 16-Dec-15 2015_12 FBgn0023124 anon-10Aj anon-10Aj http://flybase.net/reports/FBgn0023124.html gene 2 16-Dec-15 2015_12 FBgn0041249 Gr22f Gustatory receptor 22f http://flybase.net/reports/FBgn0041249.html FBgn0051932 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 22B.1, GR22b1, CG31932, GR22f, 22B.1, Gr22B1, GR22B.1" IPR013604=7TM chemoreceptor CG31932 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0083156 S(smoDN)1378 Suppressor of smoDN 1378 http://flybase.net/reports/FBgn0083156.html gene 16-Dec-15 2015_12 FBgn0023479 Tequila Tequila http://flybase.net/reports/FBgn0023479.html "FBgn0025714, FBgn0026292, FBgn0029083, FBgn0035961, FBgn0035962, FBgn0035963, FBgn0043819" protein_coding_gene "0004252=serine-type endopeptidase activity, 0008061=chitin binding, 0005044=scavenger receptor activity" "0007616=long-term memory, 0007614=short-term memory, 0006030=chitin metabolic process, 0006508=proteolysis" "0016020=membrane, 0005576=extracellular region" "anon-EST:ParkEST161, CK00198, CG18403, BEST:CK00198, CG4821, CG4948, SP72, graal, teq, tequila, Teq, CG18153, BEST:GH18038" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002557=Chitin binding domain, IPR001190=SRCR domain, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR017448=SRCR-like domain" CG4821 16-Dec-15 2015_12 "viable,fertile,memory defective,feeding behavior defective,RU486 conditional,partially lethal - majority die,some die during pupal stage" FBgn0043990 Su(rst)E122 Su(rst)E122 http://flybase.net/reports/FBgn0043990.html gene 0001745=compound eye morphogenesis E122 16-Dec-15 2015_12 FBgn0262695 Su(VGlut)B17 http://flybase.net/reports/FBgn0262695.html gene B17 16-Dec-15 2015_12 FBgn0005280 M(3)96A Minute (3) 96A http://flybase.net/reports/FBgn0005280.html gene 16-Dec-15 2015_12 FBgn0260996 CG42597 http://flybase.net/reports/FBgn0260996.html protein_coding_gene CG42597 16-Dec-15 2015_12 FBgn0034177 CG6796 http://flybase.net/reports/FBgn0034177.html protein_coding_gene "0005524=ATP binding, 0004816=asparagine-tRNA ligase activity, 0003676=nucleic acid binding" 0006421=asparaginyl-tRNA aminoacylation 0005737=cytoplasm "IPR004364=Aminoacyl-tRNA synthetase, class II (D/K/N), IPR002312=Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR018150=Aminoacyl-tRNA synthetase, class II (D/K/N)-like, IPR012340=Nucleic acid-binding, OB-fold, IPR004522=Asparagine-tRNA ligase, IPR004365=OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR006195=Aminoacyl-tRNA synthetase, class II" CG6796 16-Dec-15 2015_12 ENSDARG00000062614(zgc:153218) YCR024C(SLM5) WBGene00013447(Y66D12A.23) ENSMUSG00000018995(Nars2) ENSG00000137513(NARS2) viable FBgn0085626 CG41344 http://flybase.net/reports/FBgn0085626.html FBan0041344 protein_coding_gene 16-Dec-15 2015_12 FBgn0034154 CG5267 http://flybase.net/reports/FBgn0034154.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG5267 16-Dec-15 2015_12 viable FBgn0002599 M(2)39F Minute (2) 39F http://flybase.net/reports/FBgn0002599.html gene "M(2)H, M(2L)H, M(2)S5, M(2)S12" 16-Dec-15 2015_12 "developmental rate defective,dominant,visible,Minute" macrochaeta FBgn0265061 CR44172 http://flybase.net/reports/FBgn0265061.html non_protein_coding_gene CR44172 16-Dec-15 2015_12 FBgn0058416 CG40416 http://flybase.net/reports/FBgn0058416.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031920 CG6441 http://flybase.net/reports/FBgn0031920.html FBgn0044585 protein_coding_gene anon-WO0140519.45 "IPR009818=Ataxin-2, C-terminal" CG6441 16-Dec-15 2015_12 viable FBgn0028610 l(2)W15 lethal (2) W15 http://flybase.net/reports/FBgn0028610.html gene l(2R)W15 16-Dec-15 2015_12 "lethal,recessive" FBgn0053403 5SrRNA:CR33403 5SrRNA:CR33403 http://flybase.net/reports/FBgn0053403.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33403 CR33403 16-Dec-15 2015_12 FBgn0040393 CG14265 http://flybase.net/reports/FBgn0040393.html "FBgn0029652, FBgn0063017" protein_coding_gene "EG:96G10.8, BcDNA:RE43371" CG14265 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0267302 CR45738 http://flybase.net/reports/FBgn0267302.html non_protein_coding_gene CR45738 16-Dec-15 2015_12 FBgn0053450 5SrRNA:CR33450 5SrRNA:CR33450 http://flybase.net/reports/FBgn0053450.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33450 CR33450 16-Dec-15 2015_12 FBgn0015577 ë±-Est9 ë±-Esterase-9 http://flybase.net/reports/FBgn0015577.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0004104=cholinesterase activity" "fragment J, unnamed, Est9, alpha-Est9, Dm_3R:18691, aE9, J, alphaE9, CG1128, DmalphaE9" "IPR002018=Carboxylesterase, type B, IPR000997=Cholinesterase, IPR019826=Carboxylesterase type B, active site, IPR029058=Alpha/Beta hydrolase fold" CG1128 16-Dec-15 2015_12 "WBGene00020891(T28C12.4),WBGene00020892(T28C12.5)" viable FBgn0259787 l(2)914 http://flybase.net/reports/FBgn0259787.html gene 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" FBgn0264743 CG44001 http://flybase.net/reports/FBgn0264743.html FBgn0031674 protein_coding_gene "Dromel_CG31919_FBtr0079006_mORF, CG5822, CG31919" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG44001 16-Dec-15 2015_12 FBgn0042092 CG13773 http://flybase.net/reports/FBgn0042092.html FBgn0031867 protein_coding_gene BEST:GH23590 CG13773 16-Dec-15 2015_12 ENSDARG00000024416(twistnb) YOR340C(RPA43) ENSMUSG00000020561(Twistnb) ENSG00000105849(TWISTNB) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0058061 CG40061 http://flybase.net/reports/FBgn0058061.html protein_coding_gene 16-Dec-15 2015_12 FBgn0016674 Khc::Ggal\MLCK Khc::Ggal\MLCK http://flybase.net/reports/FBgn0016674.html engineered_fusion_gene 16-Dec-15 2015_12 "viable,neuroanatomy defective" "longitudinal connective,thoracic-abdominal embryonic fiber tract,vMP2 tract,MP1 tract,thoracic-abdominal pioneer tract,dMP2 neuron,vMP2 neuron,MP1 neuron,pCC neuron,intersegmental nerve" FBgn0024266 acd(2)5F3 auditory courtship defective 5F3 http://flybase.net/reports/FBgn0024266.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0033394 CG13740 http://flybase.net/reports/FBgn0033394.html protein_coding_gene 16-Dec-15 2015_12 FBgn0062525 l(3)88EFg lethal (3) 88EFg http://flybase.net/reports/FBgn0062525.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017416 bac backwards http://flybase.net/reports/FBgn0017416.html gene 0007409=axonogenesis 16-Dec-15 2015_12 "chordotonal organ & axon | lateral,commissure" FBgn0085717 CG41599 http://flybase.net/reports/FBgn0085717.html FBan0041599 protein_coding_gene 16-Dec-15 2015_12 FBgn0063424 l(2)44CDa lethal (2) 44CDa http://flybase.net/reports/FBgn0063424.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005077 fs(2)OW801 female sterile (2) OW801 http://flybase.net/reports/FBgn0005077.html gene 16-Dec-15 2015_12 FBgn0036094 CG14153 http://flybase.net/reports/FBgn0036094.html protein_coding_gene CG14153 16-Dec-15 2015_12 viable FBgn0026628 noco noco http://flybase.net/reports/FBgn0026628.html gene 0007417=central nervous system development 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,longitudinal connective" FBgn0001026 fs(3)A17 female sterile (3) A17 http://flybase.net/reports/FBgn0001026.html gene 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oocyte" FBgn0035800 CG7716 http://flybase.net/reports/FBgn0035800.html protein_coding_gene 0005200=structural constituent of cytoskeleton 0007020=microtubule nucleation "0000922=spindle pole, 0005813=centrosome" IPR007259=Gamma-tubulin complex component protein CG7716 16-Dec-15 2015_12 ENSXETG00000000787(TUBGCP2) viable FBgn0264660 short-round short round http://flybase.net/reports/FBgn0264660.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0020642 Lcp65Ac Lcp65Ac http://flybase.net/reports/FBgn0020642.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "Lcp-c, CG6956, DMLCP65c, DCP2, LCP65Ac" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG6956 16-Dec-15 2015_12 " embryonic stage , larval stage , pupal stage | 7-13 hr " "partially lethal - majority die,some die during pupal stage,viable" FBgn0004063 cwi crumpled wings http://flybase.net/reports/FBgn0004063.html gene 16-Dec-15 2015_12 "visible,heat sensitive" wing FBgn0263498 CR43487 http://flybase.net/reports/FBgn0263498.html non_protein_coding_gene lincRNA.695 CR43487 16-Dec-15 2015_12 FBgn0050056 CG30056 http://flybase.net/reports/FBgn0050056.html "FBgn0045109, FBgn0045372, FBgn0045381" protein_coding_gene "NEST:bs33g02, NEST:bs07h07, NEST:bs07b11" CG30056 16-Dec-15 2015_12 viable FBgn0067344 l(3)L1M lethal (3) L1M http://flybase.net/reports/FBgn0067344.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0266870 CR45331 http://flybase.net/reports/FBgn0266870.html non_protein_coding_gene CR45331 16-Dec-15 2015_12 FBgn0260013 blv bolivar http://flybase.net/reports/FBgn0260013.html gene 0030717=karyosome formation 16-Dec-15 2015_12 "chorion | germline clone,karyosome,chorion" FBgn0060846 l(3)S048718 lethal (3) S048718 http://flybase.net/reports/FBgn0060846.html gene 0487/18 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267365 l(2)SH0834 lethal (2) SH0834 http://flybase.net/reports/FBgn0267365.html "FBgn0065612, FBgn0032215" protein_coding_gene "CG5385, l(2)SH2 0834" CG5385 16-Dec-15 2015_12 DRSC02854 E -0.941651068 -0.655406794 0.217581508 -1.940626876 -0.241153634 0.739493771 FBgn0000178 bhe broad head http://flybase.net/reports/FBgn0000178.html gene 0008258=head involution 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" embryonic head FBgn0027636 ms(1)12 male sterile (1) 12 http://flybase.net/reports/FBgn0027636.html gene 16-Dec-15 2015_12 "male sterile,female fertile" FBgn0040896 CG14775 http://flybase.net/reports/FBgn0040896.html FBgn0047297 protein_coding_gene BcDNA:GH26828 16-Dec-15 2015_12 FBgn0040937 CG15248 http://flybase.net/reports/FBgn0040937.html protein_coding_gene 16-Dec-15 2015_12 FBgn0069192 l(3)L0189 lethal (3) L0189 http://flybase.net/reports/FBgn0069192.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052240 CG32240 http://flybase.net/reports/FBgn0052240.html "FBgn0045833, FBgn0064977" protein_coding_gene "BcDNA:GH04494, BEST:GH04494" CG32240 16-Dec-15 2015_12 viable FBgn0035263 CG12035 http://flybase.net/reports/FBgn0035263.html protein_coding_gene CG12035 16-Dec-15 2015_12 viable DRSC08238 E -0.486994658 -0.395484099 -1.576903366 -0.100743413 -0.131672173 -0.34905406 FBgn0019714 l(2)46CFn lethal (2) 46CFn http://flybase.net/reports/FBgn0019714.html gene "unnamed, 19.22, Complementation group N" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval digestive system,presumptive embryonic/larval tracheal system" FBgn0265731 CR44538 http://flybase.net/reports/FBgn0265731.html non_protein_coding_gene "incRNA.488, lincRNA.488" CR44538 16-Dec-15 2015_12 FBgn0264691 Lst8 http://flybase.net/reports/FBgn0264691.html "FBgn0086734, FBgn0030142" protein_coding_gene 0003924=GTPase activity "0031929=TOR signaling, 0045793=positive regulation of cell size" "0005737=cytoplasm, 0005834=heterotrimeric G-protein complex" "lst8, dLST8, dGbetaL, Gbl, CG3004" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat" CG3004 16-Dec-15 2015_12 ENSDARG00000003167(mlst8) YNL006W(LST8) WBGene00015697(C10H11.8) ENSXETG00000016102(gbl) ENSMUSG00000024142(Mlst8) ENSG00000167965(MLST8) FBgn0014239 l(2)31Fa lethal (2) 31Fa http://flybase.net/reports/FBgn0014239.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000934 fs(2)A4 female sterile (2) A4 http://flybase.net/reports/FBgn0000934.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0265765 CR44572 http://flybase.net/reports/FBgn0265765.html non_protein_coding_gene CR44572 16-Dec-15 2015_12 FBgn0267726 CG46059 http://flybase.net/reports/FBgn0267726.html protein_coding_gene "CR17567, CG17567" CG46059 16-Dec-15 2015_12 FBgn0065552 l(2)SH1033 lethal (2) SH1033 http://flybase.net/reports/FBgn0065552.html gene l(2)SH2 1033 16-Dec-15 2015_12 "lethal,recessive" FBgn0032513 CG6565 http://flybase.net/reports/FBgn0032513.html protein_coding_gene "0008289=lipid binding, 0008525=phosphatidylcholine transporter activity" "IPR023393=START-like domain, IPR002913=START domain" CG6565 16-Dec-15 2015_12 ENSXETG00000004319(STARD7) ENSMUSG00000027367(Stard7) ENSG00000084090(STARD7) FBgn0028079 l(3)S086112 lethal (3) S086112 http://flybase.net/reports/FBgn0028079.html gene 0861/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0027621 Pfrx 6-phosphofructo-2-kinase http://flybase.net/reports/FBgn0027621.html protein_coding_gene "0005524=ATP binding, 0003873=6-phosphofructo-2-kinase activity, 0004331=fructose-2,6-bisphosphate 2-phosphatase activity" "0006096=glycolytic process, 0007476=imaginal disc-derived wing morphogenesis, 0046835=carbohydrate phosphorylation, 0006003=fructose 2,6-bisphosphate metabolic process, 0006000=fructose metabolic process" 0005737=cytoplasm "fi-phosphofructo-2-kinase, CG3400, fructose 2,6 bisphosphatase, PFK2, phosphofructokinase" "IPR013079=6-phosphofructo-2-kinase, IPR003094=Fructose-2,6-bisphosphatase, IPR013078=Histidine phosphatase superfamily, clade-1, IPR001345=Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR029033=Histidine phosphatase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG3400 16-Dec-15 2015_12 "ENSDARG00000037140(pfkfb1),ENSDARG00000015810(LOC555486),ENSDARG00000029075(pfkfb4l),ENSDARG00000055540(pfkfb4),ENSDARG00000001953(pfkfb3),ENSDARG00000002037(LOC564852)" YJL155C(FBP26) "WBGene00022456(Y110A7A.6),WBGene00019295(K02B2.1)" "ENSXETG00000022029(PFKFB1),ENSXETG00000009362(pfkfb4),ENSXETG00000017108(PFKFB2),ENSXETG00000018121(PFKFB3)" "ENSMUSG00000025271(Pfkfb1),ENSMUSG00000025648(Pfkfb4),ENSMUSG00000026773(Pfkfb3),ENSMUSG00000026409(Pfkfb2)" "ENSG00000158571(PFKFB1),ENSG00000114268(PFKFB4),ENSG00000170525(PFKFB3),ENSG00000123836(PFKFB2)" "chemical resistant,viable,sleep defective,partially lethal - majority die,visible,partially lethal,conditional" mesothoracic tergum FBgn0046319 412\sORF2 sORF2 http://flybase.net/reports/FBgn0046319.html transposable_element_gene 16-Dec-15 2015_12 FBgn0036929 CG7668 http://flybase.net/reports/FBgn0036929.html "FBgn0047111, FBgn0062483" protein_coding_gene 0046331=lateral inhibition "FBpp0074674, AAF49079, BcDNA:GM07843, AAM11109, BcDNA:RE40293, AAN11645, Fibrinogen-related protein, FBpp0074673" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain" CG7668 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0052170 CG32170 http://flybase.net/reports/FBgn0052170.html FBgn0064895 protein_coding_gene "CT12913, BcDNA:RE28470" CG32170 16-Dec-15 2015_12 viable FBgn0026301 anon-7Ab anon-7Ab http://flybase.net/reports/FBgn0026301.html gene t2 16-Dec-15 2015_12 FBgn0085598 CG41283 http://flybase.net/reports/FBgn0085598.html FBan0041283 protein_coding_gene 16-Dec-15 2015_12 FBgn0015897 anon-99Da anon-99Da http://flybase.net/reports/FBgn0015897.html gene Gene 1 16-Dec-15 2015_12 FBgn0036392 CG17363 http://flybase.net/reports/FBgn0036392.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031289 CG13950 http://flybase.net/reports/FBgn0031289.html protein_coding_gene 0030246=carbohydrate binding "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001079=Galectin, carbohydrate recognition domain" CG13950 16-Dec-15 2015_12 viable FBgn0002826 ms(2)E5 male sterile (2) E5 http://flybase.net/reports/FBgn0002826.html gene "ms2.5, ms(2)2.5" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0044403 Scim24 Sensitized chromosome inheritance modifier 24 http://flybase.net/reports/FBgn0044403.html gene "0007076=mitotic chromosome condensation, 0007067=mitotic nuclear division, 0016321=female meiosis chromosome segregation" 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" mitosis & nuclear chromosome FBgn0000702 fltH flight defective H http://flybase.net/reports/FBgn0000702.html gene 16-Dec-15 2015_12 flightless "myofibril,flight muscle,Z disc,striated muscle thin filament,striated muscle myosin thick filament,sarcomere" FBgn0067732 l(1)G0502 lethal (1) G0502 http://flybase.net/reports/FBgn0067732.html gene 16-Dec-15 2015_12 lethal FBgn0013709 mt:tRNA:W mitochondrial tryptophan tRNA http://flybase.net/reports/FBgn0013709.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "tRNA[Trp], tRNAtrp, mtdbD00006295, CR34064" CR34064 16-Dec-15 2015_12 FBgn0266676 CR45166 http://flybase.net/reports/FBgn0266676.html non_protein_coding_gene CR45166 16-Dec-15 2015_12 FBgn0035438 PHGPx PHGPx http://flybase.net/reports/FBgn0035438.html FBgn0063799 protein_coding_gene "0004601=peroxidase activity, 0004602=glutathione peroxidase activity" "0006982=response to lipid hydroperoxide, 0006979=response to oxidative stress, 0055114=oxidation-reduction process" "0012505=endomembrane system, 0005737=cytoplasm, 0005794=Golgi apparatus, 0005739=mitochondrion" "DmPHGPx, PGTPx, DmGPx, glutathione peroxidase I, CG12013, phGpx, glutathione peroxidase, GTPx, anon-WO0257455.17, Gtpx-1, GPx, Glutathione Peroxidase, GTPx-1" "IPR012336=Thioredoxin-like fold, IPR000889=Glutathione peroxidase" CG12013 16-Dec-15 2015_12 "ENSDARG00000013302(zgc:56280),ENSDARG00000020415" "YBR244W(GPX2),YIR037W(HYR1),YKL026C(GPX1)" "WBGene00011045(R05H10.5),WBGene00009165(F26E4.12),WBGene00019846(R03G5.5)" ENSXETG00000007753() ENSMUSG00000075706(Gpx4) ENSG00000167468(GPX4) oxidative stress response defective FBgn0011116 l(1)Q77 lethal (1) Q77 http://flybase.net/reports/FBgn0011116.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0261736 EC2519 http://flybase.net/reports/FBgn0261736.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0014879 Set Set http://flybase.net/reports/FBgn0014879.html protein_coding_gene 0030332=cyclin binding 0006334=nucleosome assembly 0005634=nucleus "SET, CG4299, dSet, dSET, TAF-Ibeta" IPR002164=Nucleosome assembly protein (NAP) CG4299 16-Dec-15 2015_12 "ENSDARG00000003920(setb),ENSDARG00000031495(seta)" WBGene00005007(spr-2) ENSXETG00000012863(SET) "ENSMUSG00000054766(Set),ENSMUSG00000078159" ENSG00000119335(SET) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0020010 Fas1::Nrg Fas1::Nrg http://flybase.net/reports/FBgn0020010.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0058191 CG40191 http://flybase.net/reports/FBgn0058191.html "FBgn0043801, FBgn0063162, FBan0040191" protein_coding_gene "BcDNA:LD12604, BEST:HL02313, unnamed" IPR013763=Cyclin-like CG40191 16-Dec-15 2015_12 ENSDARG00000027078(c2orf24) WBGene00017311(F09G2.2) ENSMUSG00000033159(1810031K17Rik) ENSG00000115649(CNPPD1) DRSC21041 I -1.926119769 -0.024157811 -0.166481402 -0.005783387 0.773604807 0.282398526 FBgn0003198 rags rags http://flybase.net/reports/FBgn0003198.html gene 0001700=embryonic development via the syncytial blastoderm rag 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0037100 CapaR Capability receptor http://flybase.net/reports/FBgn0037100.html protein_coding_gene "0004930=G-protein coupled receptor activity, 0008188=neuropeptide receptor activity, 0001607=neuromedin U receptor activity" "0007589=body fluid secretion, 0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway, 0051928=positive regulation of calcium ion transport, 0071465=cellular response to desiccation" "0005887=integral component of plasma membrane, 0016323=basolateral plasma membrane, 0016021=integral component of membrane" "capa receptor, CAP2B-R, Capa receptor, capaR, Dm CG14575, CG14575, capa peptide receptor, CAPA receptor, CapaR" "IPR005390=Neuromedin U receptor, IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG14575 16-Dec-15 2015_12 "ENSDARG00000003944,ENSDARG00000022570(LOC566750)" WBGene00019616(nmur-2) ENSXETG00000001947(NMUR2) "ENSMUSG00000037393(Nmur2),ENSMUSG00000026237(Nmur1)" "ENSG00000132911(NMUR2),ENSG00000171596(NMUR1)" starvation stress response defective FBgn0037038 CG11037 http://flybase.net/reports/FBgn0037038.html protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space SP191 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG11037 16-Dec-15 2015_12 FBgn0004053 zen zerknullt http://flybase.net/reports/FBgn0004053.html "FBgn0013967, FBgn0019915" protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0010629=negative regulation of gene expression, 0009950=dorsal/ventral axis specification, 0007378=amnioserosa formation, 0007450=dorsal/ventral pattern formation, imaginal disc, 0048749=compound eye development, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "Zerknullt, ZEN VRE, zerknult, zerknullt 1, Zen, ZEN, CG1046, l(3)84Ad, dm-zen, zerknuellt, zen1, BG:DS00276.9, z1" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR020479=Homeodomain, metazoa" CG1046 16-Dec-15 2015_12 "ENSDARG00000023031(hoxa2b),ENSDARG00000000175(hoxb2a)" "WBGene00000452(ceh-31),WBGene00000451(ceh-30)" "ENSXETG00000010505(PHOX2A),ENSXETG00000021083(PHOX2B)" " embryonic stage | extended germ band , embryonic stage | stage 3 , embryonic stage | embryonic cycle 14 , embryonic stage , embryonic stage | stage 7-10 , embryonic stage | stage 4-6 , embryonic stage | stage 6-7 , embryonic stage | gastrula , embryonic stage | stage 4 " " dorsal ectoderm | restricted

, pole cell | restricted

,

dorsal <&> anterior embryo <&> posterior embryo , dorsal ectoderm

, amnioserosa primordium

,organism | dorsal , amnioserosa

" embryonic stage | stage 3-11 dorsal ectoderm | restricted

"lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal,heat sensitive,viable,recessive" "optic lobe,embryonic head,extended germ band embryo,cuticle,denticle belt,presumptive embryonic/larval central nervous system,ectoderm,dorsal,embryonic head epidermis,embryonic optic lobe primordium,retina,ventral" FBgn0041706 CG3253 http://flybase.net/reports/FBgn0041706.html FBgn0034977 protein_coding_gene "0008532=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity" "BEST:GH04269, dibeta3GnT1, L-gene" CG3253 16-Dec-15 2015_12 "WBGene00009032(F21H7.10),WBGene00017723(F22F7.6),WBGene00010694(K08H2.9),WBGene00011779(T15D6.4),WBGene00010167(F56H6.6),WBGene00008290(C54C8.2),WBGene00015982(C18G1.3)" ENSXETG00000020571() ENSMUSG00000047379(B3gnt1) ENSG00000174684(B3GNT1) viable FBgn0000244 by blistery http://flybase.net/reports/FBgn0000244.html "FBgn0021752, FBgn0037704, FBgn0047068" protein_coding_gene 0003779=actin binding "0007476=imaginal disc-derived wing morphogenesis, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0007016=cytoskeletal anchoring at plasma membrane" 0005925=focal adhesion "BcDNA:RE65113, 3R-B, tensin, CT26639, Tensin, CG9379" "IPR000980=SH2 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR013625=Tensin phosphotyrosine-binding domain" CG9379 16-Dec-15 2015_12 ENSDARG00000020845(LOC100334067) WBGene00006508(tag-163) "ENSXETG00000005595(TNS1),ENSXETG00000001823(TENC1)" "ENSMUSG00000020422(Tns3),ENSMUSG00000037003(Tenc1)" "ENSG00000136205(TNS3),ENSG00000111077(TENC1),ENSG00000079308(TNS1)" " larval stage | third instar , embryonic stage -- adult stage " " dorsal mesothoracic disc

, organism

" "visible,female sterile,partially,recessive,viable,somatic clone,increased cell death" "wing,thorax,somatic clone,distal,wing disc" FBgn0082192 arr::LpR2 arr::LpR2 http://flybase.net/reports/FBgn0082192.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0259445 C904.1 http://flybase.net/reports/FBgn0259445.html gene 16-Dec-15 2015_12 visible wing FBgn0263463 snoRNA:gcl-a http://flybase.net/reports/FBgn0263463.html snoRNA_gene ncRNA_47 CR43578 16-Dec-15 2015_12 FBgn0266099 CG44836 http://flybase.net/reports/FBgn0266099.html "FBgn0036628, FBgn0036626" protein_coding_gene "CG13035, rugose, CG13036" CG44836 16-Dec-15 2015_12 ENSDARG00000070281 ENSXETG00000021094(NSUN7) ENSMUSG00000029206(Nsun7) ENSG00000179299(NSUN7) FBgn0263409 CR43455 http://flybase.net/reports/FBgn0263409.html non_protein_coding_gene CR43455 16-Dec-15 2015_12 FBgn0013488 l(1)6PP19 lethal (1) 6PP19 http://flybase.net/reports/FBgn0013488.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg" FBgn0260620 2L2834 http://flybase.net/reports/FBgn0260620.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0027974 l(3)S140410 lethal (3) S140410 http://flybase.net/reports/FBgn0027974.html gene l(3)s140410 16-Dec-15 2015_12 "lethal,recessive" FBgn0266268 FeCH Ferrochelatase http://flybase.net/reports/FBgn0266268.html "FBgn0266190, FBgn0024891" protein_coding_gene 0004325=ferrochelatase activity 0006782=protoporphyrinogen IX biosynthetic process "0005875=microtubule associated complex, 0005743=mitochondrial inner membrane" "ferrochelatase, CG2098" "IPR019772=Ferrochelatase, active site, IPR001015=Ferrochelatase" CG2098 16-Dec-15 2015_12 ENSDARG00000003462 YOR176W(HEM15) WBGene00010645(K07G5.6) ENSXETG00000020888(FECH) ENSMUSG00000024588(Fech) ENSG00000066926(FECH) FBgn0030418 CG4004 http://flybase.net/reports/FBgn0030418.html FBgn0030419 protein_coding_gene 0005634=nucleus CG18137 IPR006578=MADF domain CG4004 16-Dec-15 2015_12 viable FBgn0022188 l(2)k05125a lethal (2) k05125a http://flybase.net/reports/FBgn0022188.html gene l(2)k05125 16-Dec-15 2015_12 "lethal,recessive" FBgn0035813 CG8492 http://flybase.net/reports/FBgn0035813.html protein_coding_gene 0003796=lysozyme activity 0019730=antimicrobial humoral response "IPR019799=Glycoside hydrolase, family 22, conserved site, IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain" CG8492 16-Dec-15 2015_12 "viable,stress response defective" DRSC21804 E 0.109284277 0.141112226 -0.361710087 -1.585771903 0.601162665 -0.427685864 FBgn0025152 ms(2)A4 ms(2)A4 http://flybase.net/reports/FBgn0025152.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0004977 Ata Arista http://flybase.net/reports/FBgn0004977.html gene "Arista, At" 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" "arista,wing hair,wing" FBgn0016836 l(1)MZ4 lethal (1) MZ4 http://flybase.net/reports/FBgn0016836.html gene M4 16-Dec-15 2015_12 "lethal,recessive" FBgn0031423 CG3557 http://flybase.net/reports/FBgn0031423.html protein_coding_gene CG3557 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0266946 CR45397 http://flybase.net/reports/FBgn0266946.html non_protein_coding_gene CR45397 16-Dec-15 2015_12 FBgn0265996 CR44771 http://flybase.net/reports/FBgn0265996.html non_protein_coding_gene lincRNA.144 CR44771 16-Dec-15 2015_12 FBgn0265965 CR44752 http://flybase.net/reports/FBgn0265965.html non_protein_coding_gene CR44752 16-Dec-15 2015_12 FBgn0265551 CR44401 http://flybase.net/reports/FBgn0265551.html non_protein_coding_gene CR44401 16-Dec-15 2015_12 FBgn0265097 CR44202 http://flybase.net/reports/FBgn0265097.html non_protein_coding_gene CG44202 CR44202 16-Dec-15 2015_12 FBgn0039265 CG11790 http://flybase.net/reports/FBgn0039265.html protein_coding_gene 0012505=endomembrane system IPR012336=Thioredoxin-like fold CG11790 16-Dec-15 2015_12 WBGene00017065(D2092.4) "viable,fertile" FBgn0053233 CG33233 http://flybase.net/reports/FBgn0053233.html FBgn0035365 protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CG12036 "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR005828=Major facilitator, sugar transporter-like" CG33233 16-Dec-15 2015_12 FBgn0037530 EMC1 ER Membrane protein Complex 1 http://flybase.net/reports/FBgn0037530.html FBgn0045351 protein_coding_gene "0012505=endomembrane system, 0072546=ER membrane protein complex" "NEST:bs09f06, CG2943" "IPR026895=ER membrane protein complex subunit 1, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR011678=Domain of unknown function DUF1620" CG2943 16-Dec-15 2015_12 ENSDARG00000057255(si:dkey-7c22.1) YCL045C(EMC1) WBGene00019209(H17B01.4) ENSXETG00000020829(KIAA0090) ENSMUSG00000078517(C230096C10Rik) ENSG00000127463(KIAA0090) viable FBgn0083004 snoRNA:ë¬28S-1175b snoRNA:ë¬28S-1175b http://flybase.net/reports/FBgn0083004.html snoRNA_gene "psi28s-1175b, CR34559" CR34559 16-Dec-15 2015_12 FBgn0058322 CG40322 http://flybase.net/reports/FBgn0058322.html protein_coding_gene 16-Dec-15 2015_12 FBgn0021922 l(2)k11241 lethal (2) k11241 http://flybase.net/reports/FBgn0021922.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004846 l(3)88Bd lethal (3) 88Bd http://flybase.net/reports/FBgn0004846.html gene l(3)M1 16-Dec-15 2015_12 lethal FBgn0000792 fs(1)de2 female sterile (1) defective eggs 2 http://flybase.net/reports/FBgn0000792.html gene de2 16-Dec-15 2015_12 female sterile "endochorion,dorsal appendage,chorion" FBgn0044332 9.35 9.35 http://flybase.net/reports/FBgn0044332.html gene 0008354=germ cell migration 16-Dec-15 2015_12 FBgn0060636 l(3)S084507b lethal (3) S084507b http://flybase.net/reports/FBgn0060636.html gene 0845/07 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031977 baf barrier to autointegration factor http://flybase.net/reports/FBgn0031977.html FBgn0046424 protein_coding_gene 0003677=DNA binding 0030717=karyosome formation "0005635=nuclear envelope, 0005654=nucleoplasm, 0005737=cytoplasm, 0005634=nucleus" "dBAF, BAF, Barrier-to-autointegration factor, anon-WO0172774.178, CG7380" "IPR004122=Barrier- to-autointegration factor, BAF" CG7380 16-Dec-15 2015_12 ENSDARG00000037009(zgc:77767) WBGene00000235(baf-1) "ENSXETG00000011430(BANF1),ENSXETG00000027034(BANF2)" ENSMUSG00000024844(Banf1) ENSG00000175334(BANF1) "lethal,recessive,neuroanatomy defective,female fertile,female sterile" "imaginal disc,embryonic/larval central nervous system,condensed nuclear chromosome,nuclear envelope,nuclear chromatin,karyosome" FBgn0046756 pncr017:3R putative noncoding RNA 017:3R http://flybase.net/reports/FBgn0046756.html FBgn0053945 non_protein_coding_gene "CR33945, BcDNA:SD10988" CR33945 16-Dec-15 2015_12 FBgn0051521 CG31521 http://flybase.net/reports/FBgn0051521.html protein_coding_gene 16-Dec-15 2015_12 FBgn0062657 EP3306 EP3306 http://flybase.net/reports/FBgn0062657.html gene EP(3)3306 16-Dec-15 2015_12 FBgn0023052 l(1)3Ak lethal (1) 3Ak http://flybase.net/reports/FBgn0023052.html gene "1200D15a, DCE-4, DCE-7" 16-Dec-15 2015_12 "lethal,recessive" FBgn0052255 Gr64f Gustatory receptor 64f http://flybase.net/reports/FBgn0052255.html "FBgn0035487, FBgn0045475, FBgn0045480" protein_coding_gene "0033041=sweet taste receptor activity, 0008527=taste receptor activity" "0050909=sensory perception of taste, 0050916=sensory perception of sweet taste, 0050912=detection of chemical stimulus involved in sensory perception of taste" 0016021=integral component of membrane "CG32255, Gr64A3, Dmel64f, Gr64, CG14988, DmGr64f, GR64f, Gustatory receptor 64A3" IPR009318=Gustatory receptor CG32255 16-Dec-15 2015_12 WBGene00001804(gur-3) "taste perception defective,viable" FBgn0036756 cln3 cln3 http://flybase.net/reports/FBgn0036756.html protein_coding_gene "0007040=lysosome organization, 0008593=regulation of Notch signaling pathway, 0015809=arginine transport, 0008340=determination of adult lifespan, 0007034=vacuolar transport, 0051453=regulation of intracellular pH, 0046328=regulation of JNK cascade, 0006979=response to oxidative stress" "0005770=late endosome, 0031301=integral component of organelle membrane, 0005764=lysosome, 0031982=vesicle" "ceroid-lipofuscinosis, neuronal 3, CG5582, CLN3" "IPR020846=Major facilitator superfamily domain, IPR018460=Batten's disease protein Cln3, subgroup, IPR003492=Batten's disease protein Cln3" CG5582 16-Dec-15 2015_12 ENSDARG00000037865(zgc:92244) YJL059W(YHC3) "WBGene00000540(cln-3.2),WBGene00000539(cln-3.1),WBGene00000541(cln-3.3)" ENSXETG00000008337(CLN3) ENSMUSG00000030720(Cln3) ENSG00000188603(CLN3) "fertile,viable,oxidative stress response defective,recessive,short lived,starvation stress response defective,female limited,visible,increased cell death,long lived" "eye,embryo | dorsal closure stage,wing disc,wing blade,wing margin,wing vein,ommatidium,interommatidial bristle" FBgn0250734 l(3)S001813 lethal (3) S001813 http://flybase.net/reports/FBgn0250734.html gene l(3)s001813 16-Dec-15 2015_12 lethal FBgn0267781 CR46112 http://flybase.net/reports/FBgn0267781.html non_protein_coding_gene CR46112 16-Dec-15 2015_12 FBgn0015899 anon-P1609-I anon-P1609-I http://flybase.net/reports/FBgn0015899.html gene 16-Dec-15 2015_12 FBgn0000642 fch fragile chorion http://flybase.net/reports/FBgn0000642.html gene 0007306=eggshell chorion assembly 16-Dec-15 2015_12 "lethal,maternal effect" chorion FBgn0039256 CG13647 http://flybase.net/reports/FBgn0039256.html protein_coding_gene 16-Dec-15 2015_12 FBgn0061034 l(3)S023941b lethal (3) S023941b http://flybase.net/reports/FBgn0061034.html gene 0239/41 16-Dec-15 2015_12 lethal FBgn0021962 l(2)k10111 lethal (2) k10111 http://flybase.net/reports/FBgn0021962.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052288 tRNA:CR32288 transfer RNA:CR32288 http://flybase.net/reports/FBgn0052288.html FBgn0060270 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR32288, tRNA:C:GCA:AE002584-c, chr3L.trna14-CysGCA, AE002584.trna14-CysGCA" CR32288 16-Dec-15 2015_12 FBgn0026565 CG1315 http://flybase.net/reports/FBgn0026565.html protein_coding_gene "0005524=ATP binding, 0004055=argininosuccinate synthase activity" "0000050=urea cycle, 0000053=argininosuccinate metabolic process, 0006526=arginine biosynthetic process" "argininosuccinate synthase, BG:DS00004.14, argininosuccinate synthase-like" "IPR018223=Argininosuccinate synthase, conserved site, IPR023434=Argininosuccinate synthase, type 1 subfamily, IPR024074=Argininosuccinate synthetase, catalytic/multimerisation domain body, IPR001518=Argininosuccinate synthase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG1315 16-Dec-15 2015_12 ENSDARG00000032564 YOL058W(ARG1) ENSXETG00000001347(Q5M8Z6_XENTR) "ENSMUSG00000076441(Ass1),ENSMUSG00000046687" ENSG00000130707(ASS1) "viable,fertile" FBgn0259352 C459 http://flybase.net/reports/FBgn0259352.html gene 16-Dec-15 2015_12 visible wing vein FBgn0022375 Pt-15A Adult protein-15A http://flybase.net/reports/FBgn0022375.html gene 16-Dec-15 2015_12 FBgn0028027 l(3)S103408 lethal (3) S103408 http://flybase.net/reports/FBgn0028027.html gene 1034/08 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0023015 l(3)S029910 lethal (3) S029910 http://flybase.net/reports/FBgn0023015.html FBgn0028016 gene "1029/10, 1064/14, 299/10, 0299/10, unnamed, l(3)S106414" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027199 l(2)23Ea lethal (2) 23Ea http://flybase.net/reports/FBgn0027199.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0037922 CG14711 http://flybase.net/reports/FBgn0037922.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR017956=AT hook, DNA-binding motif, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG14711 16-Dec-15 2015_12 WBGene00010770(K11D2.4) "ENSMUSG00000046792(Zfp787),ENSMUSG00000054716(Zfp771),ENSMUSG00000042097(Zfp239)" FBgn0033549 mms4 Methyl methanesulfonate sensitivity 4 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0033549.html protein_coding_gene "0003677=DNA binding, 0004518=nuclease activity" "EME1, CG12936" IPR006166=ERCC4 domain CG12936 16-Dec-15 2015_12 "ENSMUSG00000039055(Eme1),ENSMUSG00000073436" "ENSG00000154920(EME1),ENSG00000197774(EME2)" viable FBgn0026369 Sara Smad anchor for receptor activation http://flybase.net/reports/FBgn0026369.html FBgn0034630 protein_coding_gene "0046872=metal ion binding, 0005160=transforming growth factor beta receptor binding, 0008157=protein phosphatase 1 binding" "0007179=transforming growth factor beta receptor signaling pathway, 0048867=stem cell fate determination, 0008593=regulation of Notch signaling pathway, 0036335=intestinal stem cell homeostasis, 0008104=protein localization, 0098722=asymmetric stem cell division" 0005769=early endosome "CG15667, sara, dSARA, SARA, Smad Anchor for Receptor Activation" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR024608=Smad anchor for receptor activation, Smad-binding domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR000306=FYVE zinc finger, IPR017165=Zinc finger, FYVE-type, endofin, IPR022557=Domain of unknown function DUF3480" CG15667 16-Dec-15 2015_12 ENSXETG00000008057() ENSMUSG00000034557(Zfyve9) "ENSG00000157077(ZFYVE9),ENSG00000039319(ZFYVE16)" "neuroanatomy defective,lethal,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,increased cell death,visible,viable" "NMJ bouton | larval stage,wing vein,ectopic,posterior crossvein,wing disc,double row,triple row,wing margin,anterior compartment,posterior compartment,wing vein L5" FBgn0267213 CR45653 http://flybase.net/reports/FBgn0267213.html non_protein_coding_gene CR45653 16-Dec-15 2015_12 FBgn0066293 CheB42b Chemosensory protein B 42b http://flybase.net/reports/FBgn0066293.html "FBgn0033119, FBgn0053351" protein_coding_gene 0008289=lipid binding "0007606=sensory perception of chemical stimulus, 0043695=detection of pheromone" "0005576=extracellular region, 0005615=extracellular space" "CG33351, CG15241, CheB42b" "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG33351 16-Dec-15 2015_12 viable FBgn0035383 CG2107 http://flybase.net/reports/FBgn0035383.html protein_coding_gene 0004095=carnitine O-palmitoyltransferase activity SD01848p IPR000542=Acyltransferase ChoActase/COT/CPT CG2107 16-Dec-15 2015_12 ENSDARG00000038618(cpt2) YAR035W(YAT1) WBGene00011122(cpt-2) ENSXETG00000008070(cpt2) ENSMUSG00000028607(Cpt2) ENSG00000157184(CPT2) FBgn0040371 CG12470 http://flybase.net/reports/FBgn0040371.html "FBgn0029520, FBgn0045261, FBgn0045377" protein_coding_gene "NEST:bs07e10, NEST:bs17h08, EG:BACR37P7.5" CG12470 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0060709 l(3)S070310b lethal (3) S070310b http://flybase.net/reports/FBgn0060709.html gene 0703/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0023351 Di Dopachrome isomerase http://flybase.net/reports/FBgn0023351.html gene 0004167=dopachrome isomerase activity DI 16-Dec-15 2015_12 FBgn0038282 dpr9 defective proboscis extension response 9 http://flybase.net/reports/FBgn0038282.html "FBgn0053485, FBgn0038283, FBgn0038284, FBgn0051114, FBgn0063286" protein_coding_gene "0048149=behavioral response to ethanol, 0007606=sensory perception of chemical stimulus" "BcDNA:GH01517, CT34680, CG31114, CG33485, Dpr9, dpr9, Dpr-9, CG12601, CG14862, CG14863" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain, IPR013151=Immunoglobulin" CG33485 16-Dec-15 2015_12 "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" "hypoactive,conditional,chemical sensitive,viable" DRSC14986 E -0.247984611 -0.431636777 3.5418129 1.207681888 0.610142826 0.428325044 FBgn0014216 l(2)31Ca lethal (2) 31Ca http://flybase.net/reports/FBgn0014216.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027631 ms(1)294 ms(1)294 http://flybase.net/reports/FBgn0027631.html gene 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective" meiotic cell cycle | male FBgn0039002 CG17625 http://flybase.net/reports/FBgn0039002.html protein_coding_gene "IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain" CG17625 16-Dec-15 2015_12 "viable,fertile" FBgn0020875 anon-M53 anon-M53 http://flybase.net/reports/FBgn0020875.html gene 2-M53 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0003299 rue ruffled eye http://flybase.net/reports/FBgn0003299.html gene "ruffed eye, EdKs" 16-Dec-15 2015_12 "lethal,recessive,heat sensitive,visible" "eye,macrochaeta,heat sensitive" FBgn0041197 PH4ë±-RP prolyl-4-hydroxylase-a related protein http://flybase.net/reports/FBgn0041197.html gene 0004656=procollagen-proline 4-dioxygenase activity 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline 0016222=procollagen-proline 4-dioxygenase complex "PHa-RP, PH(II)a, PHaRP" 16-Dec-15 2015_12 FBgn0000903 fs(1)M112 female sterile (1) M112 http://flybase.net/reports/FBgn0000903.html gene fs(1)m112 16-Dec-15 2015_12 "egg,ocellar bristle" FBgn0065854 l(2)SH0300 lethal (2) SH0300 http://flybase.net/reports/FBgn0065854.html gene l(2)SH2 0300 16-Dec-15 2015_12 "lethal,recessive" FBgn0069232 gl(2L)210-31 gl(2L)210-31 http://flybase.net/reports/FBgn0069232.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "filzkorper,germline clone,maternal effect,embryonic/first instar larval cuticle" FBgn0060640 l(3)S084210b lethal (3) S084210b http://flybase.net/reports/FBgn0060640.html gene 0842/10 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0005373 x2 x2 http://flybase.net/reports/FBgn0005373.html gene 16-Dec-15 2015_12 FBgn0004986 Bridged Bridged http://flybase.net/reports/FBgn0004986.html gene Br 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" "wing,wing vein,wing vein L4" FBgn0036750 CG6034 http://flybase.net/reports/FBgn0036750.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process IPR002937=Amine oxidase CG6034 16-Dec-15 2015_12 viable FBgn0010342 Map60 Microtubule-associated protein 60 http://flybase.net/reports/FBgn0010342.html FBgn0015027 protein_coding_gene "0005515=protein binding, 0008017=microtubule binding" 0007017=microtubule-based process "0005875=microtubule associated complex, 0005813=centrosome, 0005634=nucleus" "CG1825, MAP60, DMAP 60, CP60, DMAP-60, unnamed, DMAP60, Cp60, CP-60, Centrosome associated protein 60" CG1825 16-Dec-15 2015_12 "viable,mitotic cell cycle defective" mitotic spindle | embryonic stage FBgn0001322 kno knobbyhead http://flybase.net/reports/FBgn0001322.html gene 16-Dec-15 2015_12 "visible,recessive,male fertile,reduced,viable,male" "adult head,eye,occipital foramen" FBgn0033859 fand fandango http://flybase.net/reports/FBgn0033859.html protein_coding_gene 0005515=protein binding "0006909=phagocytosis, 0008380=RNA splicing, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0071011=precatalytic spliceosome, 0000974=Prp19 complex, 0071013=catalytic step 2 spliceosome" "CG6197, fand, Xab2, Complementation group 7, Prp5, XAB2" "IPR019734=Tetratricopeptide repeat, IPR003107=HAT (Half-A-TPR) repeat, IPR011990=Tetratricopeptide-like helical domain" CG6197 16-Dec-15 2015_12 ENSDARG00000007092(xab2) YDR416W(SYF1) WBGene00016837(C50F2.3) ENSXETG00000002611(XAB2) ENSMUSG00000019470(Xab2) ENSG00000076924(XAB2) lethal DRSC06967 E -0.050016907 0.624100278 -0.551890458 1.523494889 -0.425418511 -0.750103459 FBgn0033623 CG13202 http://flybase.net/reports/FBgn0033623.html protein_coding_gene CG13202 16-Dec-15 2015_12 viable FBgn0020789 rABP50 ribosomal 'Alu-repeat' binding protein 50 http://flybase.net/reports/FBgn0020789.html gene 16-Dec-15 2015_12 FBgn0267672 CR46008 http://flybase.net/reports/FBgn0267672.html non_protein_coding_gene CR46008 16-Dec-15 2015_12 FBgn0030959 CG6961 http://flybase.net/reports/FBgn0030959.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" 2001020=regulation of response to DNA damage stimulus cg6961 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG6961 16-Dec-15 2015_12 ENSXETG00000013412(poldip3) ENSMUSG00000041815(Poldip3) FBgn0041579 AttC Attacin-C http://flybase.net/reports/FBgn0041579.html FBgn0033833 protein_coding_gene "0042742=defense response to bacterium, 0019731=antibacterial humoral response, 0006959=humoral immune response, 0009617=response to bacterium, 0006952=defense response, 0050830=defense response to Gram-positive bacterium" "0005576=extracellular region, 0005615=extracellular space" "Att, Drosophila Immune induced molecule 16, MPAC, DIM-16, C, DIM 16, CG4740, attacin-C, attacin C, attC, att C, Attacin C, Attacin, Attacin-C precursor, att, AttacinC, attacin, Attackin" "IPR005521=Attacin, C-terminal, IPR005520=Attacin, N-terminal" CG4740 16-Dec-15 2015_12 viable FBgn0002154 l(2)me lethal (2) meander http://flybase.net/reports/FBgn0002154.html gene lme 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval tracheal system,embryonic/larval salivary gland" FBgn0051467 CG31467 http://flybase.net/reports/FBgn0051467.html FBgn0037823 protein_coding_gene 0019902=phosphatase binding 0010923=negative regulation of phosphatase activity CG6471 IPR026142=Protein phosphatase 1 regulatory subunit 36 CG31467 16-Dec-15 2015_12 ENSMUSG00000052221(Gm70) ENSG00000165807(C14orf50) viable FBgn0033031 CG8245 http://flybase.net/reports/FBgn0033031.html protein_coding_gene "IPR008547=Protein of unknown function DUF829, TMEM53, IPR029058=Alpha/Beta hydrolase fold" CG8245 16-Dec-15 2015_12 ENSDARG00000038789(zgc:92204) "WBGene00015623(C09B8.4),WBGene00020402(T10B11.6)" ENSXETG00000001053(TMEM53) ENSMUSG00000048772(Tmem53) ENSG00000126106(TMEM53) viable DRSC04901 I -0.498945991 -2.257045038 -0.774888193 0.95911407 0.528937501 -0.253535406 FBgn0065123 l(3)SH144 lethal (3) SH144 http://flybase.net/reports/FBgn0065123.html gene l(2)SH3 144 16-Dec-15 2015_12 "lethal,recessive" FBgn0035889 mkg-p monkey king protein http://flybase.net/reports/FBgn0035889.html protein_coding_gene 0016779=nucleotidyltransferase activity "mkg-r, CG7163, mkgr, mkg, monkey-king" "IPR002934=Polymerase, nucleotidyl transferase domain, IPR015880=Zinc finger, C2H2-like" CG7163 16-Dec-15 2015_12 WBGene00019628(pup-2) ENSMUSG00000071645(Tut1) FBgn0016865 l(2)39ADc lethal (2) 39ADc http://flybase.net/reports/FBgn0016865.html gene K490 16-Dec-15 2015_12 lethal FBgn0037324 Orco Odorant receptor co-receptor http://flybase.net/reports/FBgn0037324.html protein_coding_gene "0015278=calcium-release channel activity, 0005549=odorant binding, 0005516=calmodulin binding, 0042803=protein homodimerization activity, 0004984=olfactory receptor activity" "0048149=behavioral response to ethanol, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell, 0042048=olfactory behavior, 0032880=regulation of protein localization, 0019236=response to pheromone, 0051291=protein heterooligomerization" "0016021=integral component of membrane, 0005886=plasma membrane, 0030425=dendrite, 0005929=cilium, 0032590=dendrite membrane" "DOR83b, OR83b, olfactory co-receptor, Olfactory coreceptor, Odorant receptor 83b, 83b, DmOrco, CG10609, Or83b, DOR45, DmORCO, olfactory receptor co-receptor, ORCO, 83A.2, odorant receptor 83b, or83b, odorant receptor coreceptor, orco, DmelOrco, OR83B, A45, vainsA, OR49" "IPR004117=Olfactory receptor, Drosophila" CG10609 16-Dec-15 2015_12 "smell perception defective,long lived,female,male,dominant,locomotor behavior defective,neurophysiology defective,chemosensitive behavior defective,viable,mating rhythm defective,behavior defective,hyperactive,conditional,hypoactive,chemical resistant,chemical sensitive" "antennal sense organ,olfactory receptor neuron,adult lateral horn type II neuron,antennal intermediate sensillum I2,embryonic/larval olfactory receptor neuron,adult olfactory receptor neuron" DRSC12358 K 0.522243793 0.068423385 0.303211691 -0.484643266 1.515488499 -0.486438237 FBgn0052057 dpr10 defective proboscis extension response 10 http://flybase.net/reports/FBgn0052057.html "FBgn0036069, FBgn0036071, FBgn0063023" protein_coding_gene 0007606=sensory perception of chemical stimulus "Dpr10, CT33762, CG14158, Dpr-10, CG14159, CG32057, dpr10, BcDNA:RE37920" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG32057 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) viable FBgn0264739 CG43997 http://flybase.net/reports/FBgn0264739.html FBgn0030811 protein_coding_gene CG12433 CG43997 16-Dec-15 2015_12 FBgn0039106 CG10301 http://flybase.net/reports/FBgn0039106.html protein_coding_gene "IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG10301 16-Dec-15 2015_12 FBgn0263659 CR43650 http://flybase.net/reports/FBgn0263659.html non_protein_coding_gene pri-mir-8 CR43650 16-Dec-15 2015_12 FBgn0015527 peng penguin http://flybase.net/reports/FBgn0015527.html protein_coding_gene 0003723=RNA binding 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces "pen, CG1685" "IPR016024=Armadillo-type fold, IPR001313=Pumilio RNA-binding repeat, IPR012959=CPL domain, IPR011989=Armadillo-like helical" CG1685 16-Dec-15 2015_12 ENSDARG00000063356 YDR496C(PUF6) WBGene00014165(puf-12) ENSXETG00000011707(KIAA0020) ENSMUSG00000041360(D19Bwg1357e) ENSG00000080608(KIAA0020) embryonic stage -- adult stage FBgn0051274 CG31274 http://flybase.net/reports/FBgn0051274.html "FBgn0064915, FBtr0083368, FBpp0082811, FBtr0083369, FBpp0082812" protein_coding_gene BcDNA:LP05795 CG31274 16-Dec-15 2015_12 FBgn0034321 CG14502 http://flybase.net/reports/FBgn0034321.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG14502 16-Dec-15 2015_12 viable FBgn0265671 CR44478 http://flybase.net/reports/FBgn0265671.html non_protein_coding_gene CR44478 16-Dec-15 2015_12 FBgn0261016 clos closca http://flybase.net/reports/FBgn0261016.html "FBgn0033432, FBgn0085393, FBgn0033433, FBgn0033435, FBgn0053479" protein_coding_gene "0007305=vitelline membrane formation involved in chorion-containing eggshell formation, 0008293=torso signaling pathway, 0007362=terminal region determination" 0005576=extracellular region "clos, CG33479, closca, CG12927, CG34364, CG1863, CG42600, CG12928" IPR009039=EAR CG42600 16-Dec-15 2015_12 FBgn0263020 CG43315 http://flybase.net/reports/FBgn0263020.html "FBan0013169, FBgn0033704" protein_coding_gene CG13169 CG43315 16-Dec-15 2015_12 FBgn0039344 CG4582 http://flybase.net/reports/FBgn0039344.html protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" 0016042=lipid catabolic process "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG4582 16-Dec-15 2015_12 viable FBgn0267051 CR45495 http://flybase.net/reports/FBgn0267051.html pseudogene_attribute CR45495 16-Dec-15 2015_12 FBgn0263050 CG43345 http://flybase.net/reports/FBgn0263050.html "FBgn0032926, FBan0009243" protein_coding_gene 0003824=catalytic activity CG9243 IPR001736=Phospholipase D/Transphosphatidylase CG43345 16-Dec-15 2015_12 embryonic/larval hemocyte | third instar larval stage FBgn0264366 CR43818 http://flybase.net/reports/FBgn0264366.html non_protein_coding_gene CR43818 16-Dec-15 2015_12 FBgn0034645 ND-B12 NADH dehydrogenase (ubiquinone) B12 subunit http://flybase.net/reports/FBgn0034645.html "FBgn0027667, FBgn0027680" protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone, 0006404=RNA import into nucleus" 0005747=mitochondrial respiratory chain complex I "CG10320, NADH:ubiquinone oxidoreductase B12 subunit, NADH-ubiquinone oxidoreductase B12 subunit, 10320, anon-EST:Posey47, NB2M, anon-EST:Posey84, NADH ubiquinone oxidoreductase B12" IPR012576=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 CG10320 16-Dec-15 2015_12 ENSXETG00000027496(ndufb3) ENSMUSG00000026032(Ndufb3) ENSG00000119013(NDUFB3) viable FBgn0065798 l(2)SH0413 lethal (2) SH0413 http://flybase.net/reports/FBgn0065798.html gene l(2)SH2 0413 16-Dec-15 2015_12 "lethal,recessive" FBgn0000626 eyh eyelisch http://flybase.net/reports/FBgn0000626.html gene 16-Dec-15 2015_12 visible eye FBgn0036460 CG5114 http://flybase.net/reports/FBgn0036460.html protein_coding_gene "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site" CG5114 16-Dec-15 2015_12 ENSDARG00000045019(LOC100330536) YIR012W(SQT1) ENSXETG00000014437(AAMP) ENSMUSG00000006299(Aamp) ENSG00000127837(AAMP) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC10482 I -1.532952799 -0.944726995 0.221737895 -0.932078526 0.32366935 0.448327039 FBgn0013282 Jhbp-30 Juvenile hormone binding protein - 30kD http://flybase.net/reports/FBgn0013282.html gene 16-Dec-15 2015_12 FBgn0042106 CG18754 http://flybase.net/reports/FBgn0042106.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP61 "IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG18754 16-Dec-15 2015_12 viable DRSC15387 IE 2.700545122 1.018025415 2.126006364 1.209857632 0.091656376 0.072972571 FBgn0267133 CR45573 http://flybase.net/reports/FBgn0267133.html non_protein_coding_gene CR45573 16-Dec-15 2015_12 FBgn0035290 dsb debris buster http://flybase.net/reports/FBgn0035290.html protein_coding_gene 0005044=scavenger receptor activity "0006952=defense response, 0090382=phagosome maturation, 0007155=cell adhesion" "0016020=membrane, 0005764=lysosome, 0045335=phagocytic vesicle, 0005887=integral component of plasma membrane" CG1887 IPR002159=CD36 antigen CG1887 16-Dec-15 2015_12 "WBGene00013039(scav-3),WBGene00013578(scav-2)" "viable,neuroanatomy defective,conditional,lethal - all die before end of embryonic stage" "dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional" FBgn0039251 Trf4-2 http://flybase.net/reports/FBgn0039251.html protein_coding_gene 0003887=DNA-directed DNA polymerase activity 0007062=sister chromatid cohesion 0005634=nucleus "CG17462, AAF56369, DmTRF4-2" "IPR002934=Polymerase, nucleotidyl transferase domain, IPR002058=PAP/25A-associated" CG17462 16-Dec-15 2015_12 "viable,fertile" FBgn0035432 ZnT63C Zinc transporter 63C http://flybase.net/reports/FBgn0035432.html protein_coding_gene 0005385=zinc ion transmembrane transporter activity "0055069=zinc ion homeostasis, 0006882=cellular zinc ion homeostasis, 0071577=zinc II ion transmembrane transport" "0016324=apical plasma membrane, 0016021=integral component of membrane, 0016323=basolateral plasma membrane, 0005886=plasma membrane" "dZnT1, CG17723, dZnT63C, cg17723, ZnT1" "IPR027469=Cation efflux protein transmembrane domain, IPR002524=Cation efflux protein" CG17723 16-Dec-15 2015_12 "ENSDARG00000005463(slc30a1),ENSDARG00000053896(zgc:162909)" "YMR243C(ZRC1),YOR316C(COT1)" WBGene00000393(cdf-1) ENSXETG00000014427(slc30a1) ENSMUSG00000037434(Slc30a1) ENSG00000170385(SLC30A1) "lethal - all die before end of larval stage,some die during larval stage,viable,fertile,some die during third instar larval stage,melanotic mass phenotype" melanotic mass DRSC21989 IE -2.056668053 -0.609320822 -3.064179068 0.258972772 0.220453203 -1.336939746 FBgn0266668 Exo84 Exo84 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266668.html "FBgn0266608, FBgn0260946, FBgn0086476, FBgn0042644, FBgn0039401, FBgn0045897, FBgn0043868" protein_coding_gene "0007269=neurotransmitter secretion, 0000916=actomyosin contractile ring contraction, 0007111=meiosis II cytokinesis, 0016080=synaptic vesicle targeting, 0043147=meiotic spindle stabilization, 0045199=maintenance of epithelial cell apical/basal polarity, 0032456=endocytic recycling, 0048812=neuron projection morphogenesis, 0007163=establishment or maintenance of cell polarity, 0016081=synaptic vesicle docking, 0007110=meiosis I cytokinesis, 0016192=vesicle-mediated transport, 0072659=protein localization to plasma membrane, 0007286=spermatid development" 0000145=exocyst "onion rings, exo84, CG6095, anon-WO0153538.55, Exo84p, onion ring, onr, DExo84" "IPR016159=Cullin repeat-like-containing domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG6095 16-Dec-15 2015_12 ENSDARG00000063211 YBR102C(EXO84) WBGene00013687(exoc-8) ENSXETG00000021410(EXOC8) ENSMUSG00000074030(Exoc8) ENSG00000116903(EXOC8) FBgn0060602 l(3)S091709 lethal (3) S091709 http://flybase.net/reports/FBgn0060602.html gene 0917/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0083317 E(smoDN)1124 Enhancer of smoDN 1124 http://flybase.net/reports/FBgn0083317.html gene 16-Dec-15 2015_12 FBgn0016673 Khc::Ggal\Cam Khc::Ggal\Cam http://flybase.net/reports/FBgn0016673.html engineered_fusion_gene Khc::mammal\Cam 16-Dec-15 2015_12 viable "dMP2 neuron,vMP2 neuron,MP1 neuron" FBgn0058383 CG40383 http://flybase.net/reports/FBgn0058383.html protein_coding_gene 16-Dec-15 2015_12 FBgn0051007 CG31007 http://flybase.net/reports/FBgn0051007.html "FBtr0085747, FBpp0085109" protein_coding_gene 0046331=lateral inhibition "IPR010625=CHCH, IPR009069=Cysteine alpha-hairpin motif superfamily" CG31007 16-Dec-15 2015_12 YMR002W(MIC17) "partially lethal - majority die,visible" "chaeta,supernumerary" FBgn0010134 l(1)tsW5 lethal (1) tsW5 http://flybase.net/reports/FBgn0010134.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0000736 fs(1)A59 female sterile (1) A59 http://flybase.net/reports/FBgn0000736.html gene 16-Dec-15 2015_12 "female sterile,recessive,female sterile soma-dependent" "egg,dorsal appendage" FBgn0013810 Dhc36C Dynein heavy chain at 36C http://flybase.net/reports/FBgn0013810.html protein_coding_gene "0004368=glycerol-3-phosphate dehydrogenase activity, 0003774=motor activity, 0042623=ATPase activity, coupled, 0003777=microtubule motor activity, 0016887=ATPase activity" "0003341=cilium movement, 0007605=sensory perception of sound, 0007018=microtubule-based movement, 0055114=oxidation-reduction process, 0006072=glycerol-3-phosphate metabolic process" "0005875=microtubule associated complex, 0009331=glycerol-3-phosphate dehydrogenase complex, 0005858=axonemal dynein complex" "Dhc, dhc, unnamed, DHC, dynein-related heavy chain polypeptide, CG5526, Dhc36c" "IPR004273=Dynein heavy chain domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000447=FAD-dependent glycerol-3-phosphate dehydrogenase, IPR024743=Dynein heavy chain, coiled coil stalk, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR003593=AAA+ ATPase domain, IPR026983=Dynein heavy chain, IPR026979=Dynein heavy chain 7, axonemal" CG5526 16-Dec-15 2015_12 ENSDARG00000060165(dnah7) ENSXETG00000022093(DNAH7) ENSMUSG00000041144 ENSG00000118997(DNAH7) " adult stage | female , adult stage | male , adult stage , embryonic stage " testis

"viable,auditory perception defective,neurophysiology defective" FBgn0085594 CG41278 http://flybase.net/reports/FBgn0085594.html FBan0041278 protein_coding_gene 16-Dec-15 2015_12 FBgn0264532 l(3)ffA http://flybase.net/reports/FBgn0264532.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0032365 CG14929 http://flybase.net/reports/FBgn0032365.html "FBgn0044692, FBgn0052953, FBtr0080239, FBpp0079826, FBtr0080240, FBpp0079827" protein_coding_gene "CG32953, anon-WO0140519.184" CG14929 16-Dec-15 2015_12 "viable,fertile" FBgn0051157 CG31157 http://flybase.net/reports/FBgn0051157.html protein_coding_gene CG31157 16-Dec-15 2015_12 viable DRSC29159 EK 0.854052555 -0.528582131 2.092233396 -0.162225655 -1.518057481 -0.643127875 FBgn0038074 Gnmt Glycine N-methyltransferase http://flybase.net/reports/FBgn0038074.html protein_coding_gene 0017174=glycine N-methyltransferase activity "1901054=sarcosine biosynthetic process, 0070328=triglyceride homeostasis, 0033353=S-adenosylmethionine cycle, 0009267=cellular response to starvation" "gnmt, CG6188" "IPR014369=Glycine/Sarcosine N-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG6188 16-Dec-15 2015_12 ENSDARG00000006840(gnmt) ENSMUSG00000002769(Gnmt) ENSG00000124713(GNMT) "viable,starvation stress response defective" FBgn0026393 Or43b Odorant receptor 43b http://flybase.net/reports/FBgn0026393.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "CG17853, DOR81, 43b, Or25A.1, OR43b, 25A.1/43, Olfactory receptor 25A.1, AN7, DOR25A.1" "IPR004117=Olfactory receptor, Drosophila" CG17853 16-Dec-15 2015_12 adult stage sensory neuron &&of antennal segment 3

"viable,fertile,smell perception defective" sensillum basiconicum DRSC07486 K 1.126410134 -0.1854825 0.90930995 -0.090260564 1.987378467 0.992276455 FBgn0043053 Ivk\pol pol http://flybase.net/reports/FBgn0043053.html transposable_element_gene "0003677=DNA binding, 0004523=RNA-DNA hybrid ribonuclease activity" 0006281=DNA repair 0005622=intracellular You\pol "IPR020847=AP endonuclease 1, binding site, IPR012337=Ribonuclease H-like domain, IPR005135=Endonuclease/exonuclease/phosphatase, IPR000477=Reverse transcriptase domain, IPR002156=Ribonuclease H domain" 16-Dec-15 2015_12 FBgn0002324 l(3)86Fc lethal (3) 86Fc http://flybase.net/reports/FBgn0002324.html gene "l(3)ck3, l(3)S063512" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" FBgn0259461 C790 http://flybase.net/reports/FBgn0259461.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta,ectopic" FBgn0261260 mgl Megalin http://flybase.net/reports/FBgn0261260.html "FBgn0085368, FBgn0085381, FBgn0030130, FBgn0030131, FBgn0044776" protein_coding_gene "0005509=calcium ion binding, 0005041=low-density lipoprotein receptor activity" "0030100=regulation of endocytosis, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0040003=chitin-based cuticle development" "0005829=cytosol, 0016324=apical plasma membrane, 0005886=plasma membrane" "CG34352, LDLR, CT7830, Dm CG34352, CG12654, LDLR-like, CG12139, CG42611, Megalin, CG15316, LDL-receptor-related protein, CG34339, SOSIE, anon-WO0140519.108" "IPR013032=EGF-like, conserved site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR001881=EGF-like calcium-binding domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR000033=LDLR class B repeat, IPR026823=Complement Clr-like EGF domain, IPR011042=Six-bladed beta-propeller, TolB-like, IPR009030=Insulin-like growth factor binding protein, N-terminal" CG42611 16-Dec-15 2015_12 WBGene00003071(lrp-1) ENSXETG00000016214(LRP2) ENSMUSG00000027070(Lrp2) ENSG00000081479(LRP2) FBgn0034229 CG4847 http://flybase.net/reports/FBgn0034229.html FBgn0046289 protein_coding_gene "0008234=cysteine-type peptidase activity, 0004197=cysteine-type endopeptidase activity" "0006508=proteolysis, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "cathepsinK, BEST:GH19547" "IPR013201=Cathepsin propeptide inhibitor domain (I29), IPR000169=Cysteine peptidase, cysteine active site, IPR013128=Peptidase C1A, IPR025661=Cysteine peptidase, asparagine active site, IPR000668=Peptidase C1A, papain C-terminal" CG4847 16-Dec-15 2015_12 viable FBgn0262457 mir-1015 mir-1015 stem loop http://flybase.net/reports/FBgn0262457.html "FBgn0250811, FBgn0262324" miRNA_gene "dme-mir-1015, CR43031, miR-1015" CR43031 16-Dec-15 2015_12 viable FBgn0028993 scro scarecrow http://flybase.net/reports/FBgn0028993.html "FBgn0040044, FBgn0040516, FBgn0042215, FBan0017594" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis" 0005634=nucleus "CG18452, scrou, mdcds_36132, CG17594, CG17595" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR020479=Homeodomain, metazoa" CG17594 16-Dec-15 2015_12 "ENSDARG00000012693,ENSDARG00000070551,ENSDARG00000010461(nkx2.1a),ENSDARG00000019835(nkx2.1b)" WBGene00001096(dsc-1) "ENSXETG00000023500(),ENSXETG00000002909()" "ENSMUSG00000001496(Nkx2-1),ENSMUSG00000054160(Nkx2-4)" "ENSG00000136352(NKX2-1),ENSG00000125816(NKX2-4)" neuroanatomy defective "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB" FBgn0085450 Snoo Sno oncogene http://flybase.net/reports/FBgn0085450.html "FBgn0031967, FBgn0065450, FBgn0031965" protein_coding_gene 0046332=SMAD binding "0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0048666=neuron development, 0048813=dendrite morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0090099=negative regulation of decapentaplegic signaling pathway" "0005634=nucleus, 0005737=cytoplasm" "SnoA, SnoI, dsnoN, lethal (2) SH1402, dsno, snoN, SnoN, Sno-oncogene, dSki, DskiL, CG7233, l(2)SH1402, CG7093, dSno, dSnoN, l(2)SH2 1402, Sno, CG34421, SnoN2" "IPR014890=c-SKI SMAD4-binding domain, IPR009061=Putative DNA-binding domain, IPR023216=Transcription regulator SKI/SnoN, IPR010919=SAND domain-like, IPR003380=Transforming protein Ski" CG34421 16-Dec-15 2015_12 "ENSDARG00000008034(skib),ENSDARG00000042151(skia),ENSDARG00000023933,ENSDARG00000022904(skilb)" "ENSXETG00000015978(SKI),ENSXETG00000009208(SKIL)" "ENSMUSG00000029050(Ski),ENSMUSG00000027660(Skil)" "ENSG00000157933(SKI),ENSG00000136603(SKIL)" FBgn0014367 nok next-of-kin http://flybase.net/reports/FBgn0014367.html gene 16-Dec-15 2015_12 FBgn0023076 Clk Clock http://flybase.net/reports/FBgn0023076.html protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0008134=transcription factor binding, 0046982=protein heterodimerization activity, 0005515=protein binding" "0003053=circadian regulation of heart rate, 0045893=positive regulation of transcription, DNA-templated, 0043066=negative regulation of apoptotic process, 0007623=circadian rhythm, 0048148=behavioral response to cocaine, 0008062=eclosion rhythm, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0045187=regulation of circadian sleep/wake cycle, sleep, 0032922=circadian regulation of gene expression, 0045475=locomotor rhythm, 0007622=rhythmic behavior, 0009266=response to temperature stimulus, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0009649=entrainment of circadian clock" "0005667=transcription factor complex, 0005737=cytoplasm, 0005634=nucleus" "dclk, CG7391, dClk, dClck, PAS1, Jerk, dCLOCK, dCLK/JRK, clock, bHLHe10, dclock, dCLK, Jrk, CLOCK, clk, jrk, dClock, CLK" "IPR001067=Nuclear translocator, IPR000014=PAS domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR001610=PAC motif" CG7391 16-Dec-15 2015_12 "ENSDARG00000011703(clock),ENSDARG00000003631(clock3),ENSDARG00000016536(npas2)" "ENSXETG00000021769(NPAS2),ENSXETG00000002385(),ENSXETG00000021064(CLOCK)" "ENSMUSG00000029238(Clock),ENSMUSG00000026077(Npas2)" "ENSG00000134852(CLOCK),ENSG00000170485(NPAS2)" "locomotor rhythm defective,viable,circadian rhythm defective,feeding behavior defective,recessive,semidominant,eclosion rhythm defective,sleep defective,visual behavior defective,dominant,behavior defective,circadian behavior defective,lethal" larval LN period neuron FBgn0034117 CG7997 http://flybase.net/reports/FBgn0034117.html protein_coding_gene 0004557=alpha-galactosidase activity "0046477=glycosylceramide catabolic process, 0016139=glycoside catabolic process, 0009311=oligosaccharide metabolic process" 0005737=cytoplasm CT24026 "IPR017853=Glycoside hydrolase superfamily, IPR000111=Glycoside hydrolase family 27/36, conserved site, IPR013785=Aldolase-type TIM barrel, IPR002241=Glycoside hydrolase, family 27, IPR013780=Glycosyl hydrolase, family 13, all-beta" CG7997 16-Dec-15 2015_12 ENSDARG00000020742(zgc:123333) WBGene00011095(gana-1) ENSXETG00000016614(NAGA) ENSMUSG00000022453(Naga) ENSG00000198951(NAGA) viable FBgn0085796 CR41539 http://flybase.net/reports/FBgn0085796.html FBan0041539 rRNA_gene CR41539 16-Dec-15 2015_12 FBgn0039923 MED26 Mediator complex subunit 26 http://flybase.net/reports/FBgn0039923.html FBgn0039922 protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006909=phagocytosis, 0006351=transcription, DNA-templated, 0006367=transcription initiation from RNA polymerase II promoter, 0010628=positive regulation of gene expression" "0005701=polytene chromosome chromocenter, 0031618=nuclear pericentric heterochromatin, 0070847=core mediator complex, 0016592=mediator complex" "CG1793, Mediator Subunit 26, Med26, CG1823, ARC 70, Arc70, dARC70" "IPR017923=Transcription factor IIS, N-terminal" CG1793 16-Dec-15 2015_12 DRSC17147 IEK -2.335622624 -2.171686628 -1.086576825 -1.836937941 1.904944065 3.320861283 FBgn0014215 l(2)31Bc lethal (2) 31Bc http://flybase.net/reports/FBgn0014215.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085411 CG34382 http://flybase.net/reports/FBgn0085411.html "FBgn0036055, FBgn0036054" protein_coding_gene "CG14166, CG14165" CG34382 16-Dec-15 2015_12 viable FBgn0010621 Cct5 T-complex Chaperonin 5 http://flybase.net/reports/FBgn0010621.html FBgn0027913 protein_coding_gene "0005524=ATP binding, 0051082=unfolded protein binding, 0042623=ATPase activity, coupled" "0090307=mitotic spindle assembly, 0006457=protein folding, 0022008=neurogenesis, 0007052=mitotic spindle organization" "0005875=microtubule associated complex, 0005832=chaperonin-containing T-complex" "l(2)06444, CG8439, TCP-1epsilon, cct5, CCT5, BcDNA:GM12270, BcDNA.GM12270, Tcp1-epsilon" "IPR027413=GroEL-like equatorial domain, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1), IPR027410=TCP-1-like chaperonin intermediate domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR002194=Chaperonin TCP-1, conserved site, IPR012718=T-complex protein 1, epsilon subunit, IPR027409=GroEL-like apical domain" CG8439 16-Dec-15 2015_12 ENSDARG00000045399(cct5) YJR064W(CCT5) WBGene00000380(cct-5) ENSXETG00000013995(cct5) ENSMUSG00000022234(Cct5) ENSG00000150753(CCT5) "lethal,recessive,partially lethal - majority die,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0014032 Sptr Sepiapterin reductase http://flybase.net/reports/FBgn0014032.html protein_coding_gene 0004757=sepiapterin reductase activity "0006729=tetrahydrobiopterin biosynthetic process, 0055114=oxidation-reduction process" "sptr, sepiapterin reductase, SR, CG12117" "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR006393=Sepiapterin reductase, IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain" CG12117 16-Dec-15 2015_12 "ENSDARG00000004406(spra),ENSDARG00000058553(LOC795445)" "ENSMUSG00000033735,ENSMUSG00000068303" ENSG00000116096(SPR) "viable,fertile" FBgn0004229 l(3)93Bc lethal (3) 93Bc http://flybase.net/reports/FBgn0004229.html gene "l(3)rlr1, rlr1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0041008 CG41132 http://flybase.net/reports/FBgn0041008.html protein_coding_gene CG12459 16-Dec-15 2015_12 FBgn0033645 CG13196 http://flybase.net/reports/FBgn0033645.html protein_coding_gene 0000902=cell morphogenesis 0016021=integral component of membrane IPR001507=Zona pellucida domain CG13196 16-Dec-15 2015_12 viable tracheal system | embryonic stage 16 FBgn0250740 l(3)S042302 lethal (3) S042302 http://flybase.net/reports/FBgn0250740.html gene l(3)s042302 16-Dec-15 2015_12 lethal FBgn0024322 Mut181 Mutant-181 http://flybase.net/reports/FBgn0024322.html gene 0007530=sex determination 16-Dec-15 2015_12 FBgn0084027 CG41466 http://flybase.net/reports/FBgn0084027.html FBan0041466 protein_coding_gene 16-Dec-15 2015_12 FBgn0061028 l(3)S024639a lethal (3) S024639a http://flybase.net/reports/FBgn0061028.html gene 0246/39 16-Dec-15 2015_12 lethal FBgn0031616 CG11932 http://flybase.net/reports/FBgn0031616.html protein_coding_gene 16-Dec-15 2015_12 FBgn0023108 anon-10Az anon-10Az http://flybase.net/reports/FBgn0023108.html gene 19 16-Dec-15 2015_12 FBgn0051550 CG31550 http://flybase.net/reports/FBgn0051550.html "FBgn0037333, FBgn0037334" protein_coding_gene 0044822=poly(A) RNA binding 0006396=RNA processing "CG12168, CG12167" "IPR000467=G-patch domain, IPR000061=SWAP/Surp" CG31550 16-Dec-15 2015_12 ENSXETG00000013044(TEgg031c04.1) ENSMUSG00000011306(Sf4) ENSG00000105705(SUGP1) viable FBgn0024212 lw long wing http://flybase.net/reports/FBgn0024212.html gene 16-Dec-15 2015_12 visible wing FBgn0051084 CR31084 http://flybase.net/reports/FBgn0051084.html FBgn0062899 non_protein_coding_gene "BcDNA:RH74240, CG31084" CR31084 16-Dec-15 2015_12 FBgn0037537 CG2767 http://flybase.net/reports/FBgn0037537.html protein_coding_gene 0008106=alcohol dehydrogenase (NADP+) activity "0055114=oxidation-reduction process, 0035220=wing disc development, 0022416=chaeta development" Aldo/keto reductase "IPR020471=Aldo/keto reductase subgroup, IPR018170=Aldo/keto reductase, conserved site, IPR001395=Aldo/keto reductase, IPR023210=NADP-dependent oxidoreductase domain" CG2767 16-Dec-15 2015_12 FBgn0266168 CR44874 http://flybase.net/reports/FBgn0266168.html non_protein_coding_gene CR44874 16-Dec-15 2015_12 FBgn0037169 CG11404 http://flybase.net/reports/FBgn0037169.html FBgn0063257 protein_coding_gene BcDNA:GH11730 CG11404 16-Dec-15 2015_12 viable FBgn0265079 CR44190 http://flybase.net/reports/FBgn0265079.html non_protein_coding_gene lincRNA.199 CR44190 16-Dec-15 2015_12 FBgn0024184 unc-4 unc-4 http://flybase.net/reports/FBgn0024184.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Paired HomeoDomain 1, DPHD-1, Unc4, CG6269, Dunc-4" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG6269 16-Dec-15 2015_12 "neuroanatomy defective,viable,visible" "chaeta,supernumerary" DRSC22074 K -0.22356879 -0.145218772 0.638486919 0.684621217 -1.680339485 -1.32180471 FBgn0002718 mell melanized-like http://flybase.net/reports/FBgn0002718.html gene 16-Dec-15 2015_12 visible "adult thorax,wing,eye,tergite" FBgn0266025 CR44790 http://flybase.net/reports/FBgn0266025.html non_protein_coding_gene lincRNA.17 CR44790 16-Dec-15 2015_12 FBgn0060728 l(3)S067712b lethal (3) S067712b http://flybase.net/reports/FBgn0060728.html gene 0677/12 16-Dec-15 2015_12 lethal FBgn0022967 snRNPD-U snRNPD-U http://flybase.net/reports/FBgn0022967.html gene "0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" D[U] 16-Dec-15 2015_12 FBgn0030837 CG8661 http://flybase.net/reports/FBgn0030837.html FBgn0063136 protein_coding_gene BcDNA:LP01183 CG8661 16-Dec-15 2015_12 viable FBgn0002189 l(3)63Ab lethal (3) 63Ab http://flybase.net/reports/FBgn0002189.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0036821 CG3961 http://flybase.net/reports/FBgn0036821.html protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity 0001676=long-chain fatty acid metabolic process "IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG3961 16-Dec-15 2015_12 "ENSDARG00000060317(wu:fa04h02),ENSDARG00000030514(acsl1),ENSDARG00000003854(zgc:101071)" YER015W(FAA2) WBGene00022037(acs-13) "ENSXETG00000016588(ACSL6),ENSXETG00000001539(acsl1)" "ENSMUSG00000018796(Acsl1),ENSMUSG00000020333(Acsl6),ENSMUSG00000024981(Acsl5)" "ENSG00000197142(ACSL5),ENSG00000164398(ACSL6),ENSG00000151726(ACSL1)" "viable,fertile" DRSC10391 IE -1.622428975 -0.143707811 2.315210167 0.302428544 -1.310459629 0.032454216 FBgn0025643 CG3588 http://flybase.net/reports/FBgn0025643.html protein_coding_gene EG:100G7.6 CG3588 16-Dec-15 2015_12 "viable,fertile" DRSC18473 K 0.532550617 0.405089508 0.290560623 0.27738661 1.129714892 -2.276060267 FBgn0034237 eIF3-S9 eIF3-S9 http://flybase.net/reports/FBgn0034237.html protein_coding_gene "0003743=translation initiation factor activity, 0031369=translation initiation factor binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0006413=translational initiation, 0006446=regulation of translational initiation" "0005852=eukaryotic translation initiation factor 3 complex, 0005829=cytosol" "eIF3 S9, CG4878, eIF3b, eIF3-s9, cg4878" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR000504=RNA recognition motif domain, IPR011400=Eukaryotic translation initiation factor 3 subunit B, IPR013979=Translation initiation factor, beta propellor-like domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG4878 16-Dec-15 2015_12 ENSDARG00000059654(eif3b) YOR361C(PRT1) WBGene00001225(eif-3.B) ENSXETG00000020593(EIF3B) ENSMUSG00000056076(Eif3b) ENSG00000106263(EIF3B) "viable,lethal" DRSC06900 EK -1.126676941 -1.278403783 -3.041365565 -4.406169217 0.759147943 2.10670504 FBgn0037571 CG11694 http://flybase.net/reports/FBgn0037571.html protein_coding_gene IPR007999=Protein of unknown function DUF745 CG11694 16-Dec-15 2015_12 viable DRSC24061 K -0.449894226 0.384366305 0.835273418 0.841928296 -1.568423904 0.330063119 FBgn0265362 CG44303 http://flybase.net/reports/FBgn0265362.html protein_coding_gene CG3184 CG44303 16-Dec-15 2015_12 FBgn0084012 CG41448 http://flybase.net/reports/FBgn0084012.html FBan0041448 protein_coding_gene 16-Dec-15 2015_12 FBgn0002402 l(3)99Dc lethal (3) 99Dc http://flybase.net/reports/FBgn0002402.html gene 16-Dec-15 2015_12 lethal FBgn0021930 l(2)k11038 lethal (2) k11038 http://flybase.net/reports/FBgn0021930.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028893 CG31819 http://flybase.net/reports/FBgn0028893.html "FBgn0051819, FBgn0061461" protein_coding_gene "BcDNA:AT12868, BG:DS02795.3" CG31819 16-Dec-15 2015_12 viable FBgn0031668 CG31917 http://flybase.net/reports/FBgn0031668.html "FBgn0031669, FBgn0047098, FBgn0051917" protein_coding_gene 0048812=neuron projection morphogenesis "0005634=nucleus, 0005737=cytoplasm, 0005700=polytene chromosome" "Dromel_CG31917_FBtr0079037_mORF, CG14038, BcDNA:RE52596, Dmp18" "IPR007529=Zinc finger, HIT-type" CG31917 16-Dec-15 2015_12 ENSDARG00000054574(zgc:112524) WBGene00016992(CD4.7) ENSXETG00000019429(znhit1) ENSMUSG00000059518(Znhit1) ENSG00000106400(ZNHIT1) DRSC02363 E 0.019076022 0.484132181 -3.067688777 -1.465305213 1.433021781 1.161602987 FBgn0267535 CR45875 http://flybase.net/reports/FBgn0267535.html non_protein_coding_gene CR45875 16-Dec-15 2015_12 FBgn0058296 CG40296 http://flybase.net/reports/FBgn0058296.html protein_coding_gene 16-Dec-15 2015_12 FBgn0028542 NimB4 Nimrod B4 http://flybase.net/reports/FBgn0028542.html FBgn0053115 protein_coding_gene 0042742=defense response to bacterium 0005576=extracellular region "nimB4, nimrodB4, NimB4, CG16882, DS00180.8, BG:DS00180.8, CT37470, nimrod B4, CG33115" IPR000742=EGF-like domain CG33115 16-Dec-15 2015_12 "ENSDARG00000038208,ENSDARG00000028168" ENSXETG00000011331(VWDE) viable FBgn0002236 l(3)68Bc lethal (3) 68Bc http://flybase.net/reports/FBgn0002236.html FBgn0002231 gene "l(3)I, Complementation group I, I, l(3)C557" 16-Dec-15 2015_12 "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051184 LSm3 http://flybase.net/reports/FBgn0051184.html "FBgn0039138, FBgn0064904" protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome, 0033962=cytoplasmic mRNA processing body assembly" "0005688=U6 snRNP, 0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex" "Lsm3, LSm3, BcDNA:RE11655, CG31184, CG5926" "IPR001163=LSM domain, eukaryotic/archaea-type, IPR010920=LSM domain" CG31184 16-Dec-15 2015_12 YLR438C-A(LSM3) WBGene00003077(lsm-3) ENSXETG00000011534(LSM3) ENSMUSG00000034192(Lsm3) ENSG00000170860(LSM3) FBgn0265186 CG44251 http://flybase.net/reports/FBgn0265186.html FBgn0033786 protein_coding_gene CG3884 "IPR024518=Domain of unknown function DUF3421, IPR006616=DM9 repeat" CG44251 16-Dec-15 2015_12 FBgn0002061 l(2)40Ff lethal (2) 40Ff http://flybase.net/reports/FBgn0002061.html gene "40Ff, 56-15, GroupVII, l(2L)D, l(2Lh)Ff" 16-Dec-15 2015_12 "lethal,dominant,recessive,partially lethal - majority die" FBgn0024721 Su(var)96B96D Su(var)96B96D http://flybase.net/reports/FBgn0024721.html gene unnamed 16-Dec-15 2015_12 FBgn0020406 Mcc Mcc http://flybase.net/reports/FBgn0020406.html gene 0008283=cell proliferation "DMCC, dMCC" 16-Dec-15 2015_12 FBgn0259579 B0741 http://flybase.net/reports/FBgn0259579.html gene 16-Dec-15 2015_12 visible "wing,chaeta" FBgn0020776 tondo tondo http://flybase.net/reports/FBgn0020776.html gene ton 16-Dec-15 2015_12 "female sterile,recessive" "follicle cell,egg,dorsal appendage" FBgn0263266 com3 http://flybase.net/reports/FBgn0263266.html gene "0007502=digestive tract mesoderm development, 0008406=gonad development" compaction defects 3 16-Dec-15 2015_12 "gonad,visceral mesoderm" FBgn0060880 l(3)S045305 lethal (3) S045305 http://flybase.net/reports/FBgn0060880.html gene 0453/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040855 CG15223 http://flybase.net/reports/FBgn0040855.html protein_coding_gene unnamed 16-Dec-15 2015_12 FBgn0040871 CG12479 http://flybase.net/reports/FBgn0040871.html protein_coding_gene 0005739=mitochondrion "Mitochondrial INner membrane Organizing System 1, Minos1a" IPR007512=Protein of unknown function DUF543 CG12479 16-Dec-15 2015_12 ENSDARG00000070217(zgc:153623) WBGene00018784(F54A3.5) ENSMUSG00000050608(2310028O11Rik) ENSG00000173436(C1orf151) FBgn0019813 fs(2)80 fs(2)80 http://flybase.net/reports/FBgn0019813.html gene 16-Dec-15 2015_12 FBgn0263848 CG43709 http://flybase.net/reports/FBgn0263848.html protein_coding_gene CG43709 16-Dec-15 2015_12 FBgn0050044 s-cup stanley-cup http://flybase.net/reports/FBgn0050044.html "FBgn0033746, FBgn0033747" protein_coding_gene "CG13152, CG13153, s-cup, CG30044, stanley-cup" CG30044 16-Dec-15 2015_12 viable FBgn0014000 Hf Helical Factor http://flybase.net/reports/FBgn0014000.html FBgn0032837 protein_coding_gene 0045087=innate immune response "CG10658, Os9, GH21, dhf, Drosophila Helical Factor, DHF, Olfactory-specific 9, helical factor" CG10658 16-Dec-15 2015_12 FBgn0015472 l(2)45ABb lethal (2) 45ABb http://flybase.net/reports/FBgn0015472.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0262370 mir-7 mir-7 stem loop http://flybase.net/reports/FBgn0262370.html "FBgn0046816, FBgn0262176" miRNA_gene "0048749=compound eye development, 0001751=compound eye photoreceptor cell differentiation, 0045747=positive regulation of Notch signaling pathway, 0045879=negative regulation of smoothened signaling pathway, 0007173=epidermal growth factor receptor signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0007307=eggshell chorion gene amplification" "CR33042, miR7, miR-7, 7, dme-miR-7-5p, Mir-7, CR42883, microRNA-7, mir7, mir-7, dme-mir-7, pri-miR-7" CR42883 16-Dec-15 2015_12 embryonic stage -- adult stage FBgn0013246 E(var)3-11 E(var)3-11 http://flybase.net/reports/FBgn0013246.html gene E-var(3)11 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0028855 CG15282 http://flybase.net/reports/FBgn0028855.html "FBgn0032547, FBgn0047164" protein_coding_gene "DS07721.3, BcDNA:RE15191, BG:DS07721.3" CG15282 16-Dec-15 2015_12 viable DRSC23090 K -0.421693563 -0.773259803 0.102128613 -0.305178565 0.632044407 1.769610313 FBgn0033784 CG13322 http://flybase.net/reports/FBgn0033784.html FBgn0062222 protein_coding_gene anon-WO0118547.137 "IPR005176=Potentiating neddylation domain, IPR014764=Defective-in-cullin neddylation protein" CG13322 16-Dec-15 2015_12 ENSDARG00000011493(zgc:154015) YLR128W(DCN1) ENSXETG00000016729(DCUN1D3) ENSMUSG00000048787(Dcun1d3) ENSG00000188215(DCUN1D3) viable FBgn0028009 l(3)S113208a lethal (3) S113208a http://flybase.net/reports/FBgn0028009.html gene "1132/08, l(3)S113208, 1132/8" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002398 l(3)96Fb lethal (3) 96Fb http://flybase.net/reports/FBgn0002398.html gene "C2, l(3)C2" 16-Dec-15 2015_12 "lethal,recessive" FBgn0025149 ms(2)A7 ms(2)A7 http://flybase.net/reports/FBgn0025149.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0040658 CG13516 http://flybase.net/reports/FBgn0040658.html FBgn0082870 protein_coding_gene "BP1036, unnamed" IPR006629=LPS-induced tumour necrosis factor alpha factor CG13516 16-Dec-15 2015_12 WBGene00013604(Y87G2A.18) FBgn0063907 Neurodegeneration-13 Neurodegeneration 13 http://flybase.net/reports/FBgn0063907.html gene ND13 16-Dec-15 2015_12 "central nervous system,eye" FBgn0005131 l(1)X20 lethal (1) X20 http://flybase.net/reports/FBgn0005131.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic epidermis,presumptive embryonic/larval central nervous system,gastrula embryo" FBgn0265447 CR44347 http://flybase.net/reports/FBgn0265447.html non_protein_coding_gene CR44347 16-Dec-15 2015_12 FBgn0034418 CG15118 http://flybase.net/reports/FBgn0034418.html FBgn0025243 protein_coding_gene 0005737=cytoplasm "anon-EST:fe1H12, anon-fast-evolving-1H12" "IPR002110=Ankyrin repeat, IPR003903=Ubiquitin interacting motif, IPR020683=Ankyrin repeat-containing domain, IPR021832=Ankyrin repeat domain-containing protein 13" CG15118 16-Dec-15 2015_12 "ENSDARG00000014652,ENSDARG00000061901(ankrd13a)" WBGene00015978(C18F10.7) "ENSXETG00000018665(Q640A6_XENTR),ENSXETG00000021327(ANKRD13B)" "ENSMUSG00000037907(Ankrd13b),ENSMUSG00000005986(Ankrd13d),ENSMUSG00000041870(Ankrd13a)" "ENSG00000198720(ANKRD13B),ENSG00000172932(ANKRD13D),ENSG00000076513(ANKRD13A)" "viable,fertile" FBgn0001694 l(1)ESHS15 lethal (1) ESHS15 http://flybase.net/reports/FBgn0001694.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267598 CR45936 http://flybase.net/reports/FBgn0267598.html non_protein_coding_gene lincRNA.600 CR45936 16-Dec-15 2015_12 FBgn0039562 Gp93 Glycoprotein 93 http://flybase.net/reports/FBgn0039562.html protein_coding_gene "0005524=ATP binding, 0051082=unfolded protein binding" "0061031=endodermal digestive tract morphogenesis, 0006950=response to stress, 0006457=protein folding, 0007494=midgut development" "0005615=extracellular space, 0005811=lipid particle, 0012505=endomembrane system" "CG5520, GP93, gp93, glycoprotein 93, Hsp90, dGRP94, CT17486, glycoprotein93, p93" "IPR020568=Ribosomal protein S5 domain 2-type fold, IPR001404=Heat shock protein Hsp90 family, IPR019805=Heat shock protein Hsp90, conserved site, IPR020575=Heat shock protein Hsp90, N-terminal, IPR003594=Histidine kinase-like ATPase, C-terminal domain" CG5520 16-Dec-15 2015_12 ENSDARG00000003570(hsp90b1) WBGene00011480(T05E11.3) ENSXETG00000005359(tra1) ENSMUSG00000020048(Hsp90b1) ENSG00000166598(HSP90B1) "viable,fertile,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,developmental rate defective" "embryonic/larval cuprophilic cell,septate junction,embryonic/larval oenocyte,embryonic/larval fat body" DRSC15827 E -0.326613733 0.895974235 1.91538078 0.147114738 -0.124336195 0.087335277 FBgn0031724 CG18266 http://flybase.net/reports/FBgn0031724.html FBgn0044575 protein_coding_gene anon-WO0140519.54 CG18266 16-Dec-15 2015_12 FBgn0005394 fs(2)lto4 female sterile (2) lto4 http://flybase.net/reports/FBgn0005394.html "FBgn0000992, FBgn0004822" gene 0007300=ovarian nurse cell to oocyte transport "fs(2)ltoQB3, fs(2)lo-E" 16-Dec-15 2015_12 female sterile FBgn0031653 Jon25Biii Jonah 25Biii http://flybase.net/reports/FBgn0031653.html FBgn0001284 protein_coding_gene "0004175=endopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "Jon25B, CG8871, Jon25, 25B, SP177, Jonah 25B" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG8871 16-Dec-15 2015_12 viable DRSC25069 K -0.078577165 0.108902711 -0.504271305 0.137678745 -2.23709514 -0.745318083 FBgn0086679 p pink http://flybase.net/reports/FBgn0086679.html "FBgn0037605, FBgn0003029" protein_coding_gene "0006726=eye pigment biosynthetic process, 0006622=protein targeting to lysosome, 0048072=compound eye pigmentation, 0060967=negative regulation of gene silencing by RNA, 0006727=ommochrome biosynthetic process" "0005737=cytoplasm, 0031084=BLOC-2 complex" "snb, CG9770, HPS5, Drosophila Hermansky-Pudlak Syndrome 5 subunit, pink, pink-peach, dHPS5, sunburst, NP_649810" "IPR017217=BLOC-2 complex, Hps5 subunit, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain" CG9770 16-Dec-15 2015_12 WBGene00012369(W09G3.6) ENSG00000110756(HPS5) FBgn0040075 rept reptin http://flybase.net/reports/FBgn0040075.html "FBgn0010908, FBgn0036854, FBgn0044525" protein_coding_gene "0005524=ATP binding, 0043141=ATP-dependent 5'-3' DNA helicase activity, 0003678=DNA helicase activity" "0016573=histone acetylation, 0006342=chromatin silencing, 0010629=negative regulation of gene expression, 0022008=neurogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0006338=chromatin remodeling, 0007095=mitotic G2 DNA damage checkpoint, 0043486=histone exchange" "0005875=microtubule associated complex, 0031011=Ino80 complex, 0035267=NuA4 histone acetyltransferase complex, 0000123=histone acetyltransferase complex, 0005634=nucleus, 0035102=PRC1 complex" "Reptin, psg10, CG9750, dReptin, REPT, drep, l(3)06945, Q9V3K3_DROME, Rept, dRep, anon-WO0142479.1, Tip48, Tip48/Reptin, rep, REP" "IPR003593=AAA+ ATPase domain, IPR010339=TIP49, C-terminal, IPR027238=RuvB-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9750 16-Dec-15 2015_12 ENSDARG00000055639(ruvbl2) YPL235W(RVB2) WBGene00020687(ruvb-2) ENSXETG00000025105(ruvbl2) ENSMUSG00000003868(Ruvbl2) ENSG00000183207(RUVBL2) "lethal,recessive,suppressor of variegation,dominant,non-suppressor of variegation,decreased cell number,somatic clone,developmental rate defective,cell autonomous,lethal - all die before end of larval stage,some die during larval stage,viable,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval midgut,leg,embryonic/larval salivary gland,embryonic/larval brain,somatic clone,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell" DRSC11388 IEK -2.702275932 -0.423170009 -0.586710865 -2.614957971 1.780186639 2.5063576 FBgn0267197 CR45637 http://flybase.net/reports/FBgn0267197.html non_protein_coding_gene CR45637 16-Dec-15 2015_12 FBgn0005453 l(1)v306 lethal (1) v306 http://flybase.net/reports/FBgn0005453.html gene l(1)306 16-Dec-15 2015_12 FBgn0022003 l(2)k09310 lethal (2) k09310 http://flybase.net/reports/FBgn0022003.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002131 l(2)K204 lethal (2) K204 http://flybase.net/reports/FBgn0002131.html gene 16-Dec-15 2015_12 lethal FBgn0028490 CG31705 http://flybase.net/reports/FBgn0028490.html "FBgn0051705, FBgn0063626" protein_coding_gene "BcDNA:GH07269, CG6528" CG31705 16-Dec-15 2015_12 viable DRSC01991 IE 1.040508387 -4.324584369 -1.217924123 -2.931299195 -0.480927052 0.352499438 FBgn0039006 Cyp6d4 Cyp6d4 http://flybase.net/reports/FBgn0039006.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" "0022416=chaeta development, 0035220=wing disc development, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "6d4, cytochrome P450, CG12800" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG12800 16-Dec-15 2015_12 "ENSDARG00000037874(LOC558473),ENSDARG00000037873(cyp3c1l2),ENSDARG00000070021(zgc:153269),ENSDARG00000015575(cyp3c1)" YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0033141 CG12831 http://flybase.net/reports/FBgn0033141.html protein_coding_gene CG12831 16-Dec-15 2015_12 viable FBgn0267412 CG45765 http://flybase.net/reports/FBgn0267412.html protein_coding_gene CG45765 16-Dec-15 2015_12 FBgn0003039 patch patched http://flybase.net/reports/FBgn0003039.html gene 16-Dec-15 2015_12 sternite FBgn0082167 pan::pygo pan::pygo http://flybase.net/reports/FBgn0082167.html engineered_fusion_gene 16-Dec-15 2015_12 "embryonic/first instar larval cuticle,denticle" FBgn0266253 CR44948 http://flybase.net/reports/FBgn0266253.html non_protein_coding_gene lincRNA.845 CR44948 16-Dec-15 2015_12 FBgn0053462 CG33462 http://flybase.net/reports/FBgn0053462.html "FBgn0034038, FBgn0050086" protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005576=extracellular region "SP41, CG30086, CG8215" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG33462 16-Dec-15 2015_12 WBGene00006621(try-3) viable DRSC22902 K -0.323571517 0.530967592 -0.041014595 -0.235753899 1.508322112 0.108144543 FBgn0083938 BG642163 BG642163 http://flybase.net/reports/FBgn0083938.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "BG642163(1a3), CG34102" CG34102 16-Dec-15 2015_12 "viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038808 Srp14 Signal recognition particle protein 14 http://flybase.net/reports/FBgn0038808.html FBgn0064879 protein_coding_gene "0008312=7S RNA binding, 0003729=mRNA binding, 0030942=endoplasmic reticulum signal peptide binding" 0006614=SRP-dependent cotranslational protein targeting to membrane "0005786=signal recognition particle, endoplasmic reticulum targeting" "CG5417, BcDNA:RE48595, Srp14" "IPR003210=Signal recognition particle, SRP14 subunit, IPR009018=Signal recognition particle, SRP9/SRP14 subunit" CG5417 16-Dec-15 2015_12 ENSDARG00000055935 ENSXETG00000000290(TGas091m22.1) ENSMUSG00000009549(Srp14) ENSG00000140319(SRP14) "lethal - all die before end of pupal stage,some die during pupal stage" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0041735 l(3)65AEa lethal (3) 65AEa http://flybase.net/reports/FBgn0041735.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065800 l(2)SH0410 lethal (2) SH0410 http://flybase.net/reports/FBgn0065800.html gene l(2)SH2 0410 16-Dec-15 2015_12 "lethal,recessive" FBgn0024178 y3-9 y3-9 http://flybase.net/reports/FBgn0024178.html gene 16-Dec-15 2015_12 FBgn0001019 fs(3)A10 female sterile (3) A10 http://flybase.net/reports/FBgn0001019.html gene 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oocyte" FBgn0001146 gs(2)M grandchildless M http://flybase.net/reports/FBgn0001146.html gene grandchildless on chromosome 2 of Mariol 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,partially,recessive,heat sensitive,grandchildless" "gonad,heat sensitive,pole cell" FBgn0064175 l(2)C805 lethal (2) C805 http://flybase.net/reports/FBgn0064175.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0005589 anon-alaD anon-alaD http://flybase.net/reports/FBgn0005589.html FBgn0004553 repeat_region "ALA-repeat, ala-D, ALA-D" 16-Dec-15 2015_12 FBgn0037462 sunz sungrazer http://flybase.net/reports/FBgn0037462.html "FBgn0061431, FBgn0064987" protein_coding_gene 0005509=calcium ion binding 0007140=male meiosis "BcDNA:AT31060, CG15179" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR028846=Recoverin family" CG15179 16-Dec-15 2015_12 FBgn0038693 unc79 http://flybase.net/reports/FBgn0038693.html "FBgn0045876, FBgn0046448" protein_coding_gene "0072347=response to anesthetic, 0045475=locomotor rhythm" "dunc79, anon-WO0172774.15, CG5237, DUNC79, anon-WO0153538.74, UNC79" "IPR024855=UNC79, IPR016024=Armadillo-type fold" CG5237 16-Dec-15 2015_12 WBGene00006811(unc-79) ENSXETG00000010308(KIAA1409) ENSMUSG00000021198(Unc79) ENSG00000133958(KIAA1409) "viable,fertile,circadian behavior defective,chemical sensitive,locomotor behavior defective" adult abdomen FBgn0260021 guantanamera guantanamera http://flybase.net/reports/FBgn0260021.html gene 16-Dec-15 2015_12 chorion | germline clone FBgn0038798 Or92a Odorant receptor 92a http://flybase.net/reports/FBgn0038798.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" 0007608=sensory perception of smell "0032590=dendrite membrane, 0016021=integral component of membrane" "92E.1, DOR111, Or92A, 92a, OR 92a, CG17916" "IPR004117=Olfactory receptor, Drosophila" CG17916 16-Dec-15 2015_12 viable FBgn0010087 Su(Dl)D107 Suppressor of Delta D107 http://flybase.net/reports/FBgn0010087.html gene 16-Dec-15 2015_12 FBgn0037143 CR7448 http://flybase.net/reports/FBgn0037143.html pseudogene_attribute 0008513=secondary active organic cation transmembrane transporter activity CG7448 IPR020846=Major facilitator superfamily domain CR7448 16-Dec-15 2015_12 FBgn0000777 fs(1)A1304 female sterile (1) A1304 http://flybase.net/reports/FBgn0000777.html gene 16-Dec-15 2015_12 female sterile FBgn0036277 CG10418 http://flybase.net/reports/FBgn0036277.html FBgn0047247 protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0022008=neurogenesis" "0071011=precatalytic spliceosome, 0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex, 0005688=U6 snRNP, 0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome" BcDNA:GM14851 "IPR001163=LSM domain, eukaryotic/archaea-type, IPR016654=U6 snRNA-associated Sm-like protein LSm2, IPR010920=LSM domain" CG10418 16-Dec-15 2015_12 ENSDARG00000070867(smx5) YBL026W(LSM2) WBGene00001808(gut-2) ENSXETG00000024077(lsm2) ENSMUSG00000007050(Lsm2) "ENSG00000172850,ENSG00000204392(LSM2),ENSG00000111987" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0060761 l(3)S063309 lethal (3) S063309 http://flybase.net/reports/FBgn0060761.html gene 0633/09 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037164 CG11438 http://flybase.net/reports/FBgn0037164.html protein_coding_gene 0008195=phosphatidate phosphatase activity "0090175=regulation of establishment of planar polarity, 0016311=dephosphorylation" 0016020=membrane "WUN-like, LPP-like, PAP2, Css1alpha" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG11438 16-Dec-15 2015_12 "ENSDARG00000059933(si:dkey-19f4.1),ENSDARG00000069940(zgc:158309),ENSDARG00000002231(LOC563806),ENSDARG00000028896(zgc:66434)" WBGene00018756(F53C3.13) "planar polarity defective,visible" "ommatidium,wing vein" FBgn0060575 l(3)S095708 lethal (3) S095708 http://flybase.net/reports/FBgn0060575.html gene 0957/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0264507 CR43906 http://flybase.net/reports/FBgn0264507.html non_protein_coding_gene CR43906 16-Dec-15 2015_12 FBgn0035673 CG6602 http://flybase.net/reports/FBgn0035673.html protein_coding_gene CG6602 16-Dec-15 2015_12 viable FBgn0060902 l(3)S043934b lethal (3) S043934b http://flybase.net/reports/FBgn0060902.html gene 0439/34 16-Dec-15 2015_12 "lethal,recessive" FBgn0263881 l(3)A57 http://flybase.net/reports/FBgn0263881.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0031315 CG14341 http://flybase.net/reports/FBgn0031315.html protein_coding_gene CG14341 16-Dec-15 2015_12 viable FBgn0259620 B0323 http://flybase.net/reports/FBgn0259620.html gene 16-Dec-15 2015_12 visible "wing hair,wing vein,unguis,tarsal segment,antennal segment,leg,arista" FBgn0003522 std staroid http://flybase.net/reports/FBgn0003522.html gene "Std, Stardust" 16-Dec-15 2015_12 "female semi-sterile,heat sensitive,male sterile,viable,reduced,small body" "eye,macrochaeta,heat sensitive,wing,thorax,wing vein L4,wing vein L5" FBgn0004654 Pgd Phosphogluconate dehydrogenase http://flybase.net/reports/FBgn0004654.html "FBgn0001395, FBgn0003073, FBgn0028299" protein_coding_gene "0050661=NADP binding, 0004616=phosphogluconate dehydrogenase (decarboxylating) activity, 0004679=AMP-activated protein kinase activity" "0055114=oxidation-reduction process, 0000187=activation of MAPK activity, 0006098=pentose-phosphate shunt" 0031588=AMP-activated protein kinase complex "6-Phosphogluconate dehydrogenase, l(1)2De, N1, EG:87B1.4, A7, 6pgdh, 6-PGD, 6-phosphogluconate dehydrogenase, Pdg, l(1)G0385, l35, 6PGD, l(1)Pgd-A, l(1)A7, l(1)Pgd, PGD, CG3724, l(1)N1, dehydrogenase, l(1)N3[90], 6Pgd, 6-Pgd, NADP-6 phosphogluconate dehydrogenase, l(1)2Dc, 6-phosphogluconate, 6-pgd, pgd, 6Pgdh, 6PGDH" "IPR006183=6-phosphogluconate dehydrogenase, IPR012284=6-phosphogluconate dehydrogenase, domain 3, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR006115=6-phosphogluconate dehydrogenase, NADP-binding, IPR028797=5'-AMP-activated protein kinase catalytic subunit alpha-1, IPR006114=6-phosphogluconate dehydrogenase, C-terminal, IPR006113=6-phosphogluconate dehydrogenase, decarboxylating, IPR006184=6-phosphogluconate-binding site, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR016040=NAD(P)-binding domain" CG3724 16-Dec-15 2015_12 ENSDARG00000015343(pgd) "YHR183W(GND1),YGR256W(GND2)" WBGene00012015(T25B9.9) ENSXETG00000022167(PGD) ENSMUSG00000028961(Pgd) ENSG00000142657(PGD) adult stage "electrophoretic variant,partially lethal - majority die,recessive,female sterile,lethal,lethal - all die before end of larval stage,some die during larval stage,maternal effect,viable,fertile" "oocyte,ovariole,germline clone,nurse cell & nucleus | germ-line clone,egg chamber,maternal effect" FBgn0000207 bot botch http://flybase.net/reports/FBgn0000207.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,embryonic segment" FBgn0020392 Nmt N-myristoyl transferase http://flybase.net/reports/FBgn0020392.html FBgn0011313 protein_coding_gene 0004379=glycylpeptide N-tetradecanoyltransferase activity "0007391=dorsal closure, 0022008=neurogenesis, 0006499=N-terminal protein myristoylation" "l(3)j1c7, Nmt1, l(3)j1C7, nmt, dNMT, 153290_at, CG7436" "IPR016181=Acyl-CoA N-acyltransferase, IPR022677=Myristoyl-CoA:protein N-myristoyltransferase, C-terminal, IPR000903=Myristoyl-CoA:protein N-myristoyltransferase, IPR022676=Myristoyl-CoA:protein N-myristoyltransferase, N-terminal, IPR022678=Myristoyl-CoA:protein N-myristoyltransferase, conserved site" CG7436 16-Dec-15 2015_12 "ENSDARG00000052966(nmt1a),ENSDARG00000021808,ENSDARG00000057206(si:dkeyp-94b4.2)" YLR195C(NMT1) WBGene00020549(nmt-1) "ENSXETG00000014634(NMT2),ENSXETG00000003237(NMT1)" "ENSMUSG00000020936(Nmt1),ENSMUSG00000026643(Nmt2)" "ENSG00000152465(NMT2),ENSG00000136448(NMT1)" "lethal,recessive,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,partially lethal - majority die,visible" "denticle belt,dorsal closure embryo,filzkorper,extended germ band embryo,cephalopharyngeal skeleton,presumptive embryonic/larval central nervous system,ventral nerve cord,presumptive embryonic/larval digestive system,embryonic leading edge cell,embryonic epidermis,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC11236 K 0.338702056 1.245028188 0.373205055 0.093269533 3.63558672 0.406519213 FBgn0266434 CG45064 http://flybase.net/reports/FBgn0266434.html protein_coding_gene CG9517 CG45064 16-Dec-15 2015_12 FBgn0022018 l(2)k09021 lethal (2) k09021 http://flybase.net/reports/FBgn0022018.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031768 CG12393 http://flybase.net/reports/FBgn0031768.html protein_coding_gene 0005515=protein binding 0007032=endosome organization 0055037=recycling endosome "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG12393 16-Dec-15 2015_12 "ENSDARG00000053257(zgc:153733),ENSDARG00000067546" FBgn0043548 anon-12Bb anon-12Bb http://flybase.net/reports/FBgn0043548.html gene cDNA F5 16-Dec-15 2015_12 FBgn0267502 5.8SrRNA:CR45842 5.8S ribosomal RNA:CR45842 http://flybase.net/reports/FBgn0267502.html rRNA_gene CR45842 CR45842 16-Dec-15 2015_12 FBgn0013240 E(var)212 E(var)212 http://flybase.net/reports/FBgn0013240.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0019967 Khc::nod Khc::nod http://flybase.net/reports/FBgn0019967.html engineered_fusion_gene "nod, Nod-KHC, Nod, unnamed" 16-Dec-15 2015_12 wild-type FBgn0035515 CG14997 http://flybase.net/reports/FBgn0035515.html FBgn0064976 protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process BcDNA:GH04863 "IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain" CG14997 16-Dec-15 2015_12 ENSDARG00000017034(sqrdl) "WBGene00008538(sqrd-1),WBGene00021183(Y9C9A.16)" ENSXETG00000022046(Sqrdl) ENSMUSG00000005803(Sqrdl) ENSG00000137767(SQRDL) "viable,fertile" FBgn0041780 Ssl2 Strictosidine synthase-like 2 http://flybase.net/reports/FBgn0041780.html FBgn0039624 protein_coding_gene 0016844=strictosidine synthase activity 0009058=biosynthetic process "DmSSl2, SSl2, CG11833" "IPR018119=Strictosidine synthase, conserved region, IPR011042=Six-bladed beta-propeller, TolB-like" CG11833 16-Dec-15 2015_12 ENSDARG00000017422(bscv) "WBGene00010197(F57C2.5),WBGene00007438(C08E8.2)" "ENSXETG00000007319(Q5FVB7_XENTR),ENSXETG00000012773(C20orf3)" ENSMUSG00000033096(2310001A20Rik) ENSG00000101474(C20orf3) viable DRSC14395 I -1.756612997 0.362420891 0.07190766 -0.344443221 0.138166162 -1.360729845 FBgn0066303 CG33932 http://flybase.net/reports/FBgn0066303.html "FBgn0031067, FBgn0052530, FBgn0053932, FBgn0061390, FBtr0089280, FBtr0089281, FBpp0088338" protein_coding_gene "CG32530-ORFB, CG12533, CG32530, BcDNA:RE70209" IPR019396=Transmembrane Fragile-X-F-associated protein CG33932 16-Dec-15 2015_12 ENSDARG00000052819(zgc:92808) WBGene00020299(T07A9.12) ENSMUSG00000078201(Tmem203) "ENSG00000187713(TMEM203),ENSG00000212862" FBgn0052515 CG32515 http://flybase.net/reports/FBgn0052515.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085784 CR41379 http://flybase.net/reports/FBgn0085784.html FBan0041379 pseudogene_attribute CR41379 16-Dec-15 2015_12 FBgn0034560 CG9235 http://flybase.net/reports/FBgn0034560.html protein_coding_gene 0004089=carbonate dehydratase activity "IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class" CG9235 16-Dec-15 2015_12 ENSXETG00000010291(PTPRG) FBgn0016708 Reg-13 Rhythmically expressed gene 13 http://flybase.net/reports/FBgn0016708.html gene "Drosophila Rhythmically expressed gene 13, Dreg-13" 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0065974 iab6-1.as iab6-1.as http://flybase.net/reports/FBgn0065974.html gene 6-1 as 16-Dec-15 2015_12 FBgn0001832 l(1)ts480 lethal (1) ts480 http://flybase.net/reports/FBgn0001832.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0060860 l(3)S047719 lethal (3) S047719 http://flybase.net/reports/FBgn0060860.html gene 0477/19 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0022752 anon-A1 anon-A1 http://flybase.net/reports/FBgn0022752.html gene A1 16-Dec-15 2015_12 FBgn0264263 CR43763 http://flybase.net/reports/FBgn0264263.html non_protein_coding_gene CR43763 16-Dec-15 2015_12 FBgn0037419 Osi12 Osiris 12 http://flybase.net/reports/FBgn0037419.html protein_coding_gene 0005887=integral component of plasma membrane "osi12, Osiris, CG1154" IPR012464=Protein of unknown function DUF1676 CG1154 16-Dec-15 2015_12 FBgn0015856 anon-13Aa anon-13Aa http://flybase.net/reports/FBgn0015856.html gene TS13 16-Dec-15 2015_12 FBgn0029947 CG1999 http://flybase.net/reports/FBgn0029947.html FBgn0044718 protein_coding_gene anon-WO0140519.160 CG1999 16-Dec-15 2015_12 FBgn0037223 TwdlU TweedleU http://flybase.net/reports/FBgn0037223.html FBan0014638 pseudogene_attribute "CG14638, CR14638" CR14638 16-Dec-15 2015_12 FBgn0260306 GSd214 http://flybase.net/reports/FBgn0260306.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0083985 CG34149 http://flybase.net/reports/FBgn0083985.html protein_coding_gene 0003677=DNA binding CG12757 IPR004210=BESS motif CG34149 16-Dec-15 2015_12 FBgn0053995 CG33995 http://flybase.net/reports/FBgn0053995.html protein_coding_gene Dromel_CG31919_FBtr0079006_uORF CG33995 16-Dec-15 2015_12 FBgn0262840 CG43204 http://flybase.net/reports/FBgn0262840.html protein_coding_gene chr2R_8318110_8318385.0 CG43204 16-Dec-15 2015_12 FBgn0022301 l(1)L62.4 lethal (1) L62.4 http://flybase.net/reports/FBgn0022301.html gene L62.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0013680 mt:ND2 mitochondrial NADH-ubiquinone oxidoreductase chain 2 http://flybase.net/reports/FBgn0013680.html FBgn0002867 protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity "0097031=mitochondrial respiratory chain complex I biogenesis, 0010918=positive regulation of mitochondrial membrane potential, 0042776=mitochondrial ATP synthesis coupled proton transport, 2001171=positive regulation of ATP biosynthetic process, 0006120=mitochondrial electron transport, NADH to ubiquinone" "0005743=mitochondrial inner membrane, 0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion, 0016021=integral component of membrane" "URF2, CG34063, nd2, NADH dehydrogenase subunit 2, nad2, ND2" "IPR001750=NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, IPR010933=NADH dehydrogenase subunit 2, C-terminal, IPR003917=NADH:ubiquinone oxidoreductase, chain 2" CG34063 16-Dec-15 2015_12 ENSDARG00000063899 ENSMUSG00000064345 ENSG00000198763 FBgn0267640 CR45978 http://flybase.net/reports/FBgn0267640.html non_protein_coding_gene lincRNA.556 CR45978 16-Dec-15 2015_12 FBgn0052602 Muc12Ea Mucin 12Ea http://flybase.net/reports/FBgn0052602.html FBgn0030561 protein_coding_gene 0005201=extracellular matrix structural constituent "0007304=chorion-containing eggshell formation, 0022008=neurogenesis" "0031012=extracellular matrix, 0042600=chorion" "CG5228, CG32602, Muc12Ea" CG32602 16-Dec-15 2015_12 ENSXETG00000004940() "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0027145 l(3)71DEb lethal (3) 71DEb http://flybase.net/reports/FBgn0027145.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0041134 l(2)44Fh lethal (2) 44Fh http://flybase.net/reports/FBgn0041134.html gene 16-Dec-15 2015_12 FBgn0030625 CG5877 http://flybase.net/reports/FBgn0030625.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" 0071013=catalytic step 2 spliceosome IPR013633=siRNA-mediated silencing protein NRDE-2 CG5877 16-Dec-15 2015_12 ENSXETG00000015708(C14orf102) ENSMUSG00000021179(BC002230) ENSG00000119720(C14orf102) "viable,fertile,visible" trichogen cell FBgn0011136 l(1)Q211 lethal (1) Q211 http://flybase.net/reports/FBgn0011136.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0005249 l(3)R260 lethal of Roberts 260 http://flybase.net/reports/FBgn0005249.html gene l(3)260 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0015821 Su(var)2-S29 Su(var)2-S29 http://flybase.net/reports/FBgn0015821.html gene 16-Dec-15 2015_12 "suppressor of variegation,dominant" pigment cell FBgn0085361 CG34332 http://flybase.net/reports/FBgn0085361.html protein_coding_gene CG34332 16-Dec-15 2015_12 FBgn0043032 l(2)42Cc lethal (2) 42Cc http://flybase.net/reports/FBgn0043032.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058256 CR40256 http://flybase.net/reports/FBgn0058256.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0034423 tbrd-2 testis-specifically expressed bromodomain containing protein-2 http://flybase.net/reports/FBgn0034423.html protein_coding_gene 0007283=spermatogenesis "0005730=nucleolus, 0016604=nuclear body, 0005634=nucleus, 0005694=chromosome, 0000790=nuclear chromatin" "7229, CG7229, tBRD-2, Gene 4" "IPR001487=Bromodomain, IPR018359=Bromodomain, conserved site, IPR027353=NET domain" CG7229 16-Dec-15 2015_12 "ENSXETG00000017067(brd2),ENSXETG00000013039(brd4),ENSXETG00000008571(BRDT),ENSXETG00000019589(brdt)" "ENSMUSG00000026918(Brd3),ENSMUSG00000024335(Brd2),ENSMUSG00000029279(Brdt)" "ENSG00000169925(BRD3),ENSG00000204256(BRD2),ENSG00000112526,ENSG00000215077,ENSG00000137948(BRDT)" viable FBgn0273453 slpr::Tak1 http://flybase.net/reports/FBgn0273453.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0031804 CG9500 http://flybase.net/reports/FBgn0031804.html protein_coding_gene 0005576=extracellular region "AAF52372, FBpp0078910, Fibrinogen-related protein" "IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1" CG9500 16-Dec-15 2015_12 ENSDARG00000060393(LOC567525) WBGene00017013(D1009.3) "ENSXETG00000019734(FGL2),ENSXETG00000016174()" "ENSMUSG00000026841(Fibcd1),ENSMUSG00000026938(Fcna),ENSMUSG00000026835(Fcnb)" "ENSG00000160339(FCN2),ENSG00000142748(FCN3),ENSG00000085265(FCN1),ENSG00000166482(MFAP4)" FBgn0039634 ë±-Man-Ib ë±-Mannosidase class I b http://flybase.net/reports/FBgn0039634.html protein_coding_gene "0005509=calcium ion binding, 0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity" 0035010=encapsulation of foreign target 0016020=membrane "alpha-Mannosidase class I b, dMas-3, alpha Mannosidase Ib, CG11874, ORE-11, mas-3" "IPR001382=Glycoside hydrolase, family 47" CG11874 16-Dec-15 2015_12 YJR131W(MNS1) "WBGene00020197(T03G11.4),WBGene00013881(ZC410.3)" ENSXETG00000000402(MAN1B1) ENSMUSG00000036646(Man1b1) "viable,fertile,immune response defective" DRSC14418 E 0.417179824 0.23203302 3.029793783 0.301880176 0.149487648 0.106651063 FBgn0032083 CG9541 http://flybase.net/reports/FBgn0032083.html protein_coding_gene "0005524=ATP binding, 0004017=adenylate kinase activity" 0006139=nucleobase-containing compound metabolic process "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000850=Adenylate kinase/UMP-CMP kinase" CG9541 16-Dec-15 2015_12 WBGene00008746(F13E6.2) ENSMUSG00000039058(Ak5) ENSG00000154027(AK5) "viable,fertile" DRSC03257 K 0.772889337 0.123674671 0.36955136 0.60960049 -0.068620609 1.829189526 FBgn0066367 diana diana http://flybase.net/reports/FBgn0066367.html gene "0048149=behavioral response to ethanol, 0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 "learning defective,memory defective,chemical sensitive" FBgn0262713 ifm(2)RS6 http://flybase.net/reports/FBgn0262713.html gene "0060361=flight, 0007527=adult somatic muscle development" 16-Dec-15 2015_12 "flightless,recessive" dorsal medial muscle FBgn0000531 E103 E103 http://flybase.net/reports/FBgn0000531.html gene 0005634=nucleus 90Bre 16-Dec-15 2015_12 FBgn0266180 CR44886 http://flybase.net/reports/FBgn0266180.html non_protein_coding_gene CR44886 16-Dec-15 2015_12 FBgn0038909 CG6569 http://flybase.net/reports/FBgn0038909.html protein_coding_gene CG6569 16-Dec-15 2015_12 viable FBgn0266024 CR44789 http://flybase.net/reports/FBgn0266024.html non_protein_coding_gene CR44789 16-Dec-15 2015_12 FBgn0001653 l(1)ds5 lethal (1) discs small 5 http://flybase.net/reports/FBgn0001653.html gene l(1)d.sml.-5 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086900 Cpr65Ax1 Cuticular protein 65Ax1 http://flybase.net/reports/FBgn0086900.html "FBgn0085299, FBgn0042115" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG34270, CG18774" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG34270 16-Dec-15 2015_12 FBgn0267547 CR45887 http://flybase.net/reports/FBgn0267547.html non_protein_coding_gene CR45887 16-Dec-15 2015_12 FBgn0000101 apb apterblister http://flybase.net/reports/FBgn0000101.html gene "0008587=imaginal disc-derived wing margin morphogenesis, 0007476=imaginal disc-derived wing morphogenesis" 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" "wing,alimentary canal" FBgn0028669 Vha100-3 Vacuolar H+ ATPase 100kD subunit 3 http://flybase.net/reports/FBgn0028669.html "FBgn0050329, FBgn0065027" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "Vha100-3, BcDNA:AT03238, vha100-3, CG30329, Vacuolar H[+] ATPase subunit 100-3" "IPR002490=V-type ATPase, V0 complex, 116kDa subunit family, IPR026028=ATPase, V0 complex, subunit 116kDa, eukaryotic" CG30329 16-Dec-15 2015_12 viable FBgn0005126 l(1)J770 lethal (1) J770 http://flybase.net/reports/FBgn0005126.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0036124 CG7839 http://flybase.net/reports/FBgn0036124.html FBgn0025205 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis" 0005634=nucleus "unnamed, anon-fast-evolving-2H6, anon-EST:fe2H6" "IPR005612=CCAAT-binding factor, IPR016024=Armadillo-type fold" CG7839 16-Dec-15 2015_12 ENSDARG00000045857 YDR060W(MAK21) WBGene00009084(F23B12.7) ENSXETG00000000654(CEBPZ) ENSMUSG00000024081(Cebpz) ENSG00000115816(CEBPZ) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0028480 CG17841 http://flybase.net/reports/FBgn0028480.html FBgn0025969 protein_coding_gene 0016021=integral component of membrane "clone 2.12, BcDNA:GH12326, anon-EST:Liang-2.12" IPR006634=TRAM/LAG1/CLN8 homology domain CG17841 16-Dec-15 2015_12 ENSDARG00000026875(LOC100331929) ENSXETG00000022464(FAM57A) "ENSMUSG00000058966(Fam57b),ENSMUSG00000069808(Fam57a)" "ENSG00000167695(FAM57A),ENSG00000149926(FAM57B)" "viable,fertile,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039086 CG16732 http://flybase.net/reports/FBgn0039086.html protein_coding_gene 0003851=2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG16732 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0036920 CG8004 http://flybase.net/reports/FBgn0036920.html protein_coding_gene 0006626=protein targeting to mitochondrion 0005741=mitochondrial outer membrane "IPR010987=Glutathione S-transferase, C-terminal-like" CG8004 16-Dec-15 2015_12 ENSDARG00000029415(mtx2) WBGene00022516(mtx-2) ENSXETG00000001802(mtx2) ENSMUSG00000027099(Mtx2) ENSG00000128654(MTX2) FBgn0013261 E(var)512 E(var)512 http://flybase.net/reports/FBgn0013261.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0264952 CR44121 http://flybase.net/reports/FBgn0264952.html non_protein_coding_gene lincRNA.S631 CR44121 16-Dec-15 2015_12 FBgn0053346 CG33346 http://flybase.net/reports/FBgn0053346.html protein_coding_gene "0016787=hydrolase activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "IPR001604=DNA/RNA non-specific endonuclease, IPR018524=DNA/RNA non-specific endonuclease, active site, IPR020821=Extracellular Endonuclease, subunit A" CG33346 16-Dec-15 2015_12 viable FBgn0025919 mei-160 mei-160 http://flybase.net/reports/FBgn0025919.html gene "0016321=female meiosis chromosome segregation, 0007131=reciprocal meiotic recombination" 16-Dec-15 2015_12 FBgn0030631 CG6227 http://flybase.net/reports/FBgn0030631.html protein_coding_gene "0003724=RNA helicase activity, 0003729=mRNA binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0005681=spliceosomal complex" "DmRH29, Prp5, cg6227" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site" CG6227 16-Dec-15 2015_12 ENSDARG00000053439(ddx46) YBR237W(PRP5) WBGene00018776(F53H1.1) ENSXETG00000010405(DDX46) ENSMUSG00000021500(Ddx46) ENSG00000145833(DDX46) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC19975 I 0.369306373 2.208352333 0.614375266 0.762608111 0.764859815 -1.096472677 FBgn0032192 CG5731 http://flybase.net/reports/FBgn0032192.html protein_coding_gene "0004557=alpha-galactosidase activity, 0008456=alpha-N-acetylgalactosaminidase activity" "0046477=glycosylceramide catabolic process, 0009311=oligosaccharide metabolic process, 0016139=glycoside catabolic process" 0005737=cytoplasm "IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR000111=Glycoside hydrolase family 27/36, conserved site, IPR017853=Glycoside hydrolase superfamily, IPR002241=Glycoside hydrolase, family 27, IPR013785=Aldolase-type TIM barrel" CG5731 16-Dec-15 2015_12 ENSDARG00000020742(zgc:123333) WBGene00011095(gana-1) ENSXETG00000016614(NAGA) ENSMUSG00000022453(Naga) ENSG00000198951(NAGA) viable FBgn0000378 crt crumpled tips http://flybase.net/reports/FBgn0000378.html gene 16-Dec-15 2015_12 "viable,visible,fertile,lethal,recessive,cell lethal,germline clone" wing FBgn0038761 CG17190 http://flybase.net/reports/FBgn0038761.html protein_coding_gene CG17190 16-Dec-15 2015_12 viable FBgn0021951 l(2)k10317 lethal (2) k10317 http://flybase.net/reports/FBgn0021951.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024552 l(3)L4060 lethal (3) L4060 http://flybase.net/reports/FBgn0024552.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022295 l(1)M76.3 lethal (1) M76.3 http://flybase.net/reports/FBgn0022295.html gene M76.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0038345 CG5213 http://flybase.net/reports/FBgn0038345.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003723=RNA binding" 0022008=neurogenesis cg5213 "IPR000504=RNA recognition motif domain, IPR002343=Paraneoplastic encephalomyelitis antigen, IPR012677=Nucleotide-binding alpha-beta plait domain" CG5213 16-Dec-15 2015_12 "YHR015W(MIP6),YFR023W(PES4)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0053447 5SrRNA:CR33447 5SrRNA:CR33447 http://flybase.net/reports/FBgn0053447.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33447 CR33447 16-Dec-15 2015_12 FBgn0033767 CG13148 http://flybase.net/reports/FBgn0033767.html protein_coding_gene CG13148 16-Dec-15 2015_12 "viable,fertile" DRSC06275 E 0.551626893 1.251402538 1.744400071 -0.75037224 -0.111677946 -0.061736654 FBgn0086285 GS32 http://flybase.net/reports/FBgn0086285.html gene 32 16-Dec-15 2015_12 FBgn0011682 P13 P13 http://flybase.net/reports/FBgn0011682.html gene Dmcks 16-Dec-15 2015_12 FBgn0031649 hoe2 hoepel2 http://flybase.net/reports/FBgn0031649.html protein_coding_gene 0005302=L-tyrosine transmembrane transporter activity 0055085=transmembrane transport "0016020=membrane, 0016021=integral component of membrane" CG15624 IPR004680=Citrate transporter-like domain CG15624 16-Dec-15 2015_12 ENSDARG00000061303(oca2) ENSXETG00000004157(OCA2) ENSMUSG00000030450(Oca2) ENSG00000104044(OCA2) viable FBgn0044069 E(rst)K45 E(rst)K45 http://flybase.net/reports/FBgn0044069.html gene 0001745=compound eye morphogenesis K45 16-Dec-15 2015_12 viable FBgn0011294 a5 antennal protein 5 http://flybase.net/reports/FBgn0011294.html protein_coding_gene 0008429=phosphatidylethanolamine binding "CG5430, A5" "IPR008914=Phosphatidylethanolamine-binding protein PEBP, IPR001858=Phosphatidylethanolamine-binding, conserved site" CG5430 16-Dec-15 2015_12 "YLR179C(),YLR178C(TFS1)" adult stage " antennal segment 3

, sensillum coeloconica of antennal segment 3

" "partially lethal - majority die,some die during pupal stage" FBgn0038720 CG6231 http://flybase.net/reports/FBgn0038720.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane Organic cation transporter "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG6231 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266062 Su(var)305 http://flybase.net/reports/FBgn0266062.html gene 305 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0038136 CG8774 http://flybase.net/reports/FBgn0038136.html protein_coding_gene "0008270=zinc ion binding, 0008237=metallopeptidase activity, 0004177=aminopeptidase activity" 0006508=proteolysis "IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571=ERAP1-like C-terminal domain" CG8774 16-Dec-15 2015_12 ENSDARG00000057064 WBGene00011587(T07F10.1) ENSXETG00000013333(ENPEP) ENSMUSG00000028024(Enpep) ENSG00000138792(ENPEP) "viable,fertile" FBgn0262877 CG43232 http://flybase.net/reports/FBgn0262877.html protein_coding_gene CG43232 16-Dec-15 2015_12 FBgn0023147 Su(mg)3-5 Suppressor of modifier of gypsy 3-5 http://flybase.net/reports/FBgn0023147.html gene 16-Dec-15 2015_12 FBgn0031902 Wnt6 Wnt oncogene analog 6 http://flybase.net/reports/FBgn0031902.html protein_coding_gene "0001664=G-protein coupled receptor binding, 0005102=receptor binding" "0060070=canonical Wnt signaling pathway, 0009798=axis specification, 0044719=regulation of imaginal disc-derived wing size, 0045893=positive regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0009952=anterior/posterior pattern specification, 0016055=Wnt signaling pathway" "0005576=extracellular region, 0005615=extracellular space, 0005886=plasma membrane" "DWnt6, wnt6, Wnt6, D-Wnt-6, CG4969, DWnt-6" "IPR018161=Wnt protein, conserved site, IPR005817=Wnt" CG4969 16-Dec-15 2015_12 "viable,size defective,fertile,visible" "wing,posterior,maxillary palpus,wing margin bristle,eye,head" FBgn0028083 l(3)S085009 lethal (3) S085009 http://flybase.net/reports/FBgn0028083.html gene 0850/09 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0027774 anon-69Db anon-69Db http://flybase.net/reports/FBgn0027774.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0031360 CG31937 http://flybase.net/reports/FBgn0031360.html FBgn0051937 protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process "CG17711, CT39259" "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR" CG31937 16-Dec-15 2015_12 ENSDARG00000003444(dhrs7) ENSXETG00000016955(dhrs7) ENSMUSG00000021094(Dhrs7) ENSG00000100612(DHRS7) viable FBgn0060881 l(3)S045002b lethal (3) S045002b http://flybase.net/reports/FBgn0060881.html gene 0450/02 16-Dec-15 2015_12 lethal FBgn0262905 CR43260 http://flybase.net/reports/FBgn0262905.html non_protein_coding_gene "CG43260, lincRNA.1020" CR43260 16-Dec-15 2015_12 FBgn0065058 snoRNA:684 snoRNA:684 http://flybase.net/reports/FBgn0065058.html FBgn0053794 snoRNA_gene 0005730=nucleolus "CR33794, snoR684, DmOr_cd6(SnoR684), Dm-684" CR33794 16-Dec-15 2015_12 FBgn0084590 gfr gang of four http://flybase.net/reports/FBgn0084590.html gene 0048749=compound eye development 16-Dec-15 2015_12 "visible,somatic clone,lethal,recessive,viable" "eye,somatic clone,primary pigment cell,cone cell,wing,wing vein L5,adult head" FBgn0026247 fldB flight defective B http://flybase.net/reports/FBgn0026247.html gene 0007517=muscle organ development AD170 16-Dec-15 2015_12 "flight defective,recessive,flightless,lethal" FBgn0037617 nom numerous disordered muscles http://flybase.net/reports/FBgn0037617.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0007526=larval somatic muscle development 0005634=nucleus "Numerous disordered muscles, CG8145" "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG8145 16-Dec-15 2015_12 WBGene00010770(K11D2.4) viable FBgn0031733 CG14006 http://flybase.net/reports/FBgn0031733.html protein_coding_gene 0004001=adenosine kinase activity 0006166=purine ribonucleoside salvage "IPR019358=NEMP family, IPR001805=Adenosine kinase, IPR029056=Ribokinase-like, IPR011611=Carbohydrate kinase PfkB" CG14006 16-Dec-15 2015_12 viable FBgn0260629 d01629 http://flybase.net/reports/FBgn0260629.html gene 16-Dec-15 2015_12 visible wing FBgn0026681 l(1)G0083 lethal (1) G0083 http://flybase.net/reports/FBgn0026681.html gene 16-Dec-15 2015_12 "partially lethal - majority die,male,female,recessive" FBgn0005230 l(3)R15 lethal of Roberts 15 http://flybase.net/reports/FBgn0005230.html gene l(3)15 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0262691 Su(VGlut)B6 http://flybase.net/reports/FBgn0262691.html gene B6 16-Dec-15 2015_12 FBgn0041088 volcano volcano http://flybase.net/reports/FBgn0041088.html gene "0001745=compound eye morphogenesis, 0008407=chaeta morphogenesis" 16-Dec-15 2015_12 FBgn0263577 mir-4910 mir-4910 stem loop http://flybase.net/reports/FBgn0263577.html miRNA_gene "dme-mir-4910, CR43562" CR43562 16-Dec-15 2015_12 FBgn0016901 l(3)72CDc lethal (3) 72CDc http://flybase.net/reports/FBgn0016901.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267678 CR46014 http://flybase.net/reports/FBgn0267678.html non_protein_coding_gene CR46014 16-Dec-15 2015_12 FBgn0020590 anon-57Cg anon-57Cg http://flybase.net/reports/FBgn0020590.html gene unnamed 16-Dec-15 2015_12 FBgn0265720 CR44527 http://flybase.net/reports/FBgn0265720.html non_protein_coding_gene "lincRNA.482, incRNA.482" CR44527 16-Dec-15 2015_12 FBgn0010044 GstD8 Glutathione S transferase D8 http://flybase.net/reports/FBgn0010044.html FBgn0038027 protein_coding_gene "0004364=glutathione transferase activity, 0004602=glutathione peroxidase activity" 0006749=glutathione metabolic process 0005737=cytoplasm "gstD8, GST, Gst, GST D27, gstd8, Glutathione S transferase D27, CG4421, GstD27, DmGSTD8, Glutathione-S-transferase, GSTD8, DmGST27, gstD27" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG4421 16-Dec-15 2015_12 YNL229C(URE2) viable FBgn0004521 l(4)102CDe lethal (4) 102CDe http://flybase.net/reports/FBgn0004521.html gene "l(4)CDe, l(4)PT-1, lethal(4) Powell, Tennessee-1, l(4)6" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260234 CG42508 http://flybase.net/reports/FBgn0260234.html protein_coding_gene CG42508 16-Dec-15 2015_12 FBgn0004556 Dbp73D Dead box protein 73D http://flybase.net/reports/FBgn0004556.html protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" 0022008=neurogenesis "CG9680, DBP73D, DmRH7" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal" CG9680 16-Dec-15 2015_12 ENSDARG00000025854(ddx51) YNR038W(DBP6) WBGene00022792(ZK686.2) ENSXETG00000022359(DDX51) ENSMUSG00000029504(Ddx51) ENSG00000185163(DDX51) " adult stage && oogenesis stage , embryonic stage&&larval stage&&adult stage " " egg chamber

, nurse cell

" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001531 l(1)11Fa lethal (1) 11Fa http://flybase.net/reports/FBgn0001531.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0052054 CG32054 http://flybase.net/reports/FBgn0052054.html "FBgn0036067, FBgn0046224" protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "BcDNA:GM13904, CG6645" "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG32054 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0025794 Su(var)503 Suppressor of variegation 503 http://flybase.net/reports/FBgn0025794.html gene Su-var(2)503 16-Dec-15 2015_12 FBgn0266928 CR45379 http://flybase.net/reports/FBgn0266928.html non_protein_coding_gene CR45379 16-Dec-15 2015_12 FBgn0038929 CG13408 http://flybase.net/reports/FBgn0038929.html protein_coding_gene CG13408 16-Dec-15 2015_12 WBGene00016809(C50D2.6) viable FBgn0261795 Ote::tkv http://flybase.net/reports/FBgn0261795.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0019935 Rsp80C Responder like http://flybase.net/reports/FBgn0019935.html repeat_region Rsp-like sequences 16-Dec-15 2015_12 FBgn0262216 mir-974 mir-974 stem loop http://flybase.net/reports/FBgn0262216.html miRNA_gene "CR42923, 974, miR-974, dme-mir-974" CR42923 16-Dec-15 2015_12 viable FBgn0003518 Stigmata Stigmata http://flybase.net/reports/FBgn0003518.html gene Sta 16-Dec-15 2015_12 "scutum,wing" FBgn0035636 Cralbp Cellular retinaldehyde binding protein http://flybase.net/reports/FBgn0035636.html protein_coding_gene "0016918=retinal binding, 0005215=transporter activity" 0006810=transport 0005622=intracellular "CG10546, CRALBP" "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG10546 16-Dec-15 2015_12 "ENSDARG00000053122(si:ch211-199i15.4),ENSDARG00000045808(rlbp1b),ENSDARG00000012504(rlbp1a)" "ENSXETG00000021635(CLVS1),ENSXETG00000023298(RLBP1L2)" "ENSMUSG00000041216(Clvs1),ENSMUSG00000019785(Clvs2),ENSMUSG00000039194(Rlbp1)" "ENSG00000177182(CLVS1),ENSG00000146352(CLVS2),ENSG00000140522(RLBP1)" FBgn0084118 1297 1297 http://flybase.net/reports/FBgn0084118.html gene 16-Dec-15 2015_12 FBgn0011640 lark lark http://flybase.net/reports/FBgn0011640.html protein_coding_gene "0003723=RNA binding, 0003676=nucleic acid binding, 0003729=mRNA binding, 0008270=zinc ion binding, 0000166=nucleotide binding" "0000398=mRNA splicing, via spliceosome, 0007623=circadian rhythm, 0030036=actin cytoskeleton organization, 0045995=regulation of embryonic development, 0048477=oogenesis, 0007562=eclosion, 0045475=locomotor rhythm, 0007067=mitotic nuclear division, 0007303=cytoplasmic transport, nurse cell to oocyte, 0008104=protein localization, 0008062=eclosion rhythm, 0040011=locomotion, 0045804=negative regulation of eclosion" "0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0005737=cytoplasm, 0071011=precatalytic spliceosome" "dLARK, LARK, CG8597, Lark" "IPR001878=Zinc finger, CCHC-type, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG8597 16-Dec-15 2015_12 "ENSDARG00000055080(rbm4.2),ENSDARG00000036386(rbm4.1),ENSDARG00000022129(zgc:56141)" WBGene00004384(rnp-1) ENSXETG00000026649(rbm4) "ENSMUSG00000033760(Rbm4b),ENSMUSG00000056951(Rbm4)" ENSG00000173914(RBM4B) "viable,eclosion rhythm defective,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective,heat sensitive,visible,flightless,female sterile,male fertile,female fertile,flight defective,lethal,recessive,behavior defective,dominant,eclosion defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die" "wing,scutellar bristle,posterior scutellar bristle,ectopic,embryo,germline clone,adult cuticle" DRSC11362 E 0.402631878 0.029104102 0.66748349 -2.107292227 -0.645745338 -0.153304046 FBgn0011934 tRNA:N5:42Ad transfer RNA:asn5:42Ad http://flybase.net/reports/FBgn0011934.html "FBgn0003759, FBgn0050319, FBgn0060127" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033442=AAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna10-AsnGTT, CR30319, tRNA:asn5:42Ad, tRNA:N:GTT:AE002769-g, AE002769.trna18-AsnGTT" CR30319 16-Dec-15 2015_12 FBgn0261241 Vps16A Vacuolar protein sorting 16A http://flybase.net/reports/FBgn0261241.html "FBgn0037674, FBgn0041173" protein_coding_gene 0019905=syntaxin binding "0016197=endosomal transport, 0007041=lysosomal transport, 0006886=intracellular protein transport, 0007033=vacuole organization, 0008057=eye pigment granule organization, 0000046=autophagic vacuole fusion, 0009267=cellular response to starvation, 0045746=negative regulation of Notch signaling pathway, 0035542=regulation of SNARE complex assembly, 0008333=endosome to lysosome transport" "0030897=HOPS complex, 0005764=lysosome, 0033263=CORVET complex, 0005776=autophagic vacuole, 0005829=cytosol, 0005768=endosome" "vps16A, Vps16, CG8454, dVps16A, V16, Vps16A, DmVps16" "IPR006925=Vps16, C-terminal, IPR016534=Vacuolar protein sorting-associated protein 16, IPR006926=Vps16, N-terminal" CG8454 16-Dec-15 2015_12 "ENSDARG00000059902(zgc:162584),ENSDARG00000071195,ENSDARG00000071146" YPL045W(VPS16) WBGene00006516(vps-16) ENSXETG00000027061(vps16) ENSMUSG00000027411(Vps16) ENSG00000215305(VPS16) FBgn0260006 drd drop dead http://flybase.net/reports/FBgn0260006.html "FBgn0000494, FBgn0069186, FBgn0053968, FBgn0027917, FBgn0052589, FBgn0086221" protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "0030421=defecation, 0048477=oogenesis, 0007586=digestion, 0009651=response to salt stress, 0022600=digestive system process, 0040003=chitin-based cuticle development" 0016021=integral component of membrane "CG33968, CG5652, drop-dead, beltless, lwf, lots wife, BcDNA:GM06434, blt, lot's wife, CG32589" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG33968 16-Dec-15 2015_12 FBgn0033259 CG11210 http://flybase.net/reports/FBgn0033259.html protein_coding_gene 0016020=membrane CT31310 "IPR003864=Calcium-dependent channel, 7TM region, putative phosphate" CG11210 16-Dec-15 2015_12 "ENSDARG00000004158(LOC100000800),ENSDARG00000003836(LOC100334023),ENSDARG00000031956(si:ch211-117l16.1)" "YOL084W(PHM7),YMR266W(RSN1)" "ENSXETG00000022650(TMEM63A),ENSXETG00000011072(TMEM63C),ENSXETG00000023485(TMEM63B)" "ENSMUSG00000036026(Tmem63b),ENSMUSG00000026519(Tmem63a),ENSMUSG00000034145(Tmem63c)" "ENSG00000137216(TMEM63B),ENSG00000196187(TMEM63A),ENSG00000165548(TMEM63C)" viable FBgn0063418 l(3)3450-E lethal (3) 3450-E http://flybase.net/reports/FBgn0063418.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0067397 Su(var)3-9::trx Su(var)3-9::trx http://flybase.net/reports/FBgn0067397.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0022238 lolal lola like http://flybase.net/reports/FBgn0022238.html "FBgn0025189, FBgn0034306, FBgn0043381, FBgn0046417" protein_coding_gene "0042803=protein homodimerization activity, 0005515=protein binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0031208=POZ domain binding" "0007426=tracheal outgrowth, open tracheal system, 0035167=larval lymph gland hemopoiesis, 0016458=gene silencing, 0006342=chromatin silencing, 0006357=regulation of transcription from RNA polymerase II promoter, 0007435=salivary gland morphogenesis" "0031519=PcG protein complex, 0005634=nucleus" "Ban, batman, l(2)kO2512, anon-WO0172774.186, EP0647, Lolal, Lola Like, LOLAL, EP647, bat, l(2)k02512, unnamed, 25/12, anon-fast-evolving-3D3, CG5738, ban, lola-like, Batman, anon-EST:fe3D3" "IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG5738 16-Dec-15 2015_12 "ENSDARG00000069621,ENSDARG00000002196(bach1)" "lethal,recessive,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "sex comb,ectopic,presumptive embryonic salivary gland,dorsal trunk primordium,macrochaeta,trichogen cell,tormogen cell,embryonic/larval brain" FBgn0035044 CG3663 http://flybase.net/reports/FBgn0035044.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process IPR000868=Isochorismatase-like CG3663 16-Dec-15 2015_12 "ENSDARG00000060069(isoc1),ENSDARG00000013371(isoc2)" WBGene00009436(F35G2.2) ENSXETG00000008281(ISOC1) ENSMUSG00000024601(Isoc1) ENSG00000066583(ISOC1) viable FBgn0265754 CR44561 http://flybase.net/reports/FBgn0265754.html non_protein_coding_gene lincRNA.550 CR44561 16-Dec-15 2015_12 FBgn0060904 l(3)S043901b lethal (3) S043901b http://flybase.net/reports/FBgn0060904.html gene 0439/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0016626 E(gl)2B Enhancer of glass 2B http://flybase.net/reports/FBgn0016626.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011081 l(1)Q39 lethal (1) Q39 http://flybase.net/reports/FBgn0011081.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0011452 l(3)neo8 lethal (3) neo8 http://flybase.net/reports/FBgn0011452.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030500 Ndc80 Ndc80 http://flybase.net/reports/FBgn0030500.html protein_coding_gene "0022008=neurogenesis, 0007052=mitotic spindle organization, 0007059=chromosome segregation, 0007080=mitotic metaphase plate congression, 0090307=mitotic spindle assembly" "0000776=kinetochore, 0031262=Ndc80 complex" "CG9938, dNdc80, NDC80, hec1, Hec1, dmNdc80" "IPR026099=Outer dense fibre protein 2-related, IPR005550=Kinetochore protein Ndc80" CG9938 16-Dec-15 2015_12 WBGene00003576(ndc-80) ENSMUSG00000024056(Ndc80) ENSG00000080986(NDC80) "mitotic cell cycle defective,female sterile,lethal,neuroanatomy defective,viable,visible,female fertile" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0250845 CG1288 http://flybase.net/reports/FBgn0250845.html "FBgn0037484, FBgn0046235, FBgn0062509, FBgn0066879" protein_coding_gene "anon-SAGE:Wang-119, BcDNA:AT26093, BEST:LP10010" CG1288 16-Dec-15 2015_12 DRSC12538 E -0.866037199 -0.632989434 0.042747043 -1.72151673 1.466689238 0.28427631 FBgn0026252 msk moleskin http://flybase.net/reports/FBgn0026252.html "FBgn0024487, FBgn0035837" protein_coding_gene "0030620=U2 snRNA binding, 0005515=protein binding, 0008320=protein transmembrane transporter activity, 0008536=Ran GTPase binding, 0030619=U1 snRNA binding, 0030621=U4 snRNA binding" "0016203=muscle attachment, 0035311=wing cell fate specification, 0007476=imaginal disc-derived wing morphogenesis, 0006606=protein import into nucleus, 0046331=lateral inhibition, 0007173=epidermal growth factor receptor signaling pathway, 0006608=snRNP protein import into nucleus, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0043524=negative regulation of neuron apoptotic process, 0016318=ommatidial rotation, 0007474=imaginal disc-derived wing vein specification, 0008586=imaginal disc-derived wing vein morphogenesis, 0000189=MAPK import into nucleus, 0030576=Cajal body organization, 0042675=compound eye cone cell differentiation, 0045465=R8 cell differentiation, 0048749=compound eye development, 0042052=rhabdomere development, 0008283=cell proliferation" "0005737=cytoplasm, 0005829=cytosol, 0048471=perinuclear region of cytoplasm, 0015030=Cajal body, 0005654=nucleoplasm, 0005634=nucleus, 0005938=cell cortex, 0005643=nuclear pore" "Msk, Corkscrew Interacting Protein-61, Moleskin, dim-7, S(ls)2, CG7935, diminished-7, Importin-7, Dim-7, dim7, importin-7, Imp7, Drosophila Importin-7, CIP-61, Dim7, 61, Imp7/8, DIM-7, DmRanBP7" "IPR013713=Exportin/Importin, Cse1-like, IPR011989=Armadillo-like helical, IPR001494=Importin-beta, N-terminal domain, IPR016024=Armadillo-type fold" CG7935 16-Dec-15 2015_12 "ENSDARG00000035751(ipo7),ENSDARG00000058159(ipo8)" YJR132W(NMD5) "ENSXETG00000024201(IPO7),ENSXETG00000007514(IPO8)" "ENSMUSG00000066232(Ipo7),ENSMUSG00000040029(Ipo8)" "ENSG00000205339(IPO7),ENSG00000133704(IPO8)" "lethal,recessive,visible,somatic clone,cell death defective,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,increased cell death,eye color defective,heat sensitive,lethal - all die during pupal stage,viable" "eye,somatic clone,ommatidium,primary pigment cell,secondary pigment cell,tertiary pigment cell,rhabdomere,cone cell,interommatidial bristle,rhabdomere R7,rhabdomere R8,ommatidial precursor cluster,photoreceptor cell R4,muscle fiber,wing,wing vein L4,wing vein L5,anterior crossvein,posterior crossvein,crossvein,heat sensitive,eye photoreceptor cell,pigment cell,muscle fiber | embryonic stage,chaeta,trichogen cell" FBgn0010167 pur1 purine requiring http://flybase.net/reports/FBgn0010167.html gene pur-1 16-Dec-15 2015_12 wing vein L4 FBgn0046122 E(To)13 E(To)13 http://flybase.net/reports/FBgn0046122.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005171 l(2)G572 lethal (2) G572 http://flybase.net/reports/FBgn0005171.html gene 16-Dec-15 2015_12 lethal FBgn0027250 l(1)G0254 lethal (1) G0254 http://flybase.net/reports/FBgn0027250.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0040554 CR17025 http://flybase.net/reports/FBgn0040554.html non_protein_coding_gene "CG17025, pri-mir-252" CR17025 16-Dec-15 2015_12 FBgn0037016 CG13252 http://flybase.net/reports/FBgn0037016.html protein_coding_gene IPR001007=VWFC domain CG13252 16-Dec-15 2015_12 viable FBgn0030032 CG15344 http://flybase.net/reports/FBgn0030032.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263612 CR43621 http://flybase.net/reports/FBgn0263612.html non_protein_coding_gene lincRNA.92 CR43621 16-Dec-15 2015_12 FBgn0044032 Mod(rst)K46 Mod(rst)K46 http://flybase.net/reports/FBgn0044032.html gene 0001745=compound eye morphogenesis K46 16-Dec-15 2015_12 FBgn0014863 Mlp84B Muscle LIM protein at 84B http://flybase.net/reports/FBgn0014863.html FBgn0011644 protein_coding_gene "0008307=structural constituent of muscle, 0008270=zinc ion binding" "0007519=skeletal muscle tissue development, 0060537=muscle tissue development, 0045214=sarcomere organization, 0090175=regulation of establishment of planar polarity, 0030154=cell differentiation" "0015629=actin cytoskeleton, 0005737=cytoplasm, 0005634=nucleus, 0030018=Z disc" "Muscle LIM protein, Muscle-specific LIM protein at 84B, DLim-3, LIM protein 84B, Mlp, MLP, Mlp84b, dMlp84B, Mlmu84B, DmLIM-3, mlp84B, mlp, CG1019, MLP84B" "IPR001781=Zinc finger, LIM-type" CG1019 16-Dec-15 2015_12 " embryonic stage -- adult stage , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage 16 " " pharyngeal muscle

, visceral mesoderm

, embryonic/larval somatic muscle

, somatic mesoderm

" embryonic stage " muscle attachment site

, pharyngeal muscle

, embryonic/larval somatic muscle

, larval visceral muscle

" "lethal,recessive,viable,visible" "pupal cuticle,muscle fiber,filamentous actin,trichogen cell,mesothoracic tergum" FBgn0001558 l(1)19Cc lethal (1) 19Cc http://flybase.net/reports/FBgn0001558.html gene "25C4, lElC1" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0060899 l(3)S044215b lethal (3) S044215b http://flybase.net/reports/FBgn0060899.html gene 0442/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000508 dsx-c88D doublesex cognate 88D http://flybase.net/reports/FBgn0000508.html gene dsx-c88 16-Dec-15 2015_12 FBgn0028592 l(3)00421 lethal (3) 00421 http://flybase.net/reports/FBgn0028592.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0004753 l(3)89Bf lethal (3) 89Bf http://flybase.net/reports/FBgn0004753.html gene 16-Dec-15 2015_12 lethal FBgn0036909 CG15881 http://flybase.net/reports/FBgn0036909.html FBgn0061418 protein_coding_gene "Ccdc58, BcDNA:HL01254" IPR019171=Caffeine-induced death protein 2 CG15881 16-Dec-15 2015_12 ENSDARG00000045351(zgc:73369) ENSXETG00000002796(CCDC58) ENSMUSG00000075229(Ccdc58) ENSG00000160124(CCDC58) "viable,fertile,immune response defective" FBgn0030807 CG13000 http://flybase.net/reports/FBgn0030807.html protein_coding_gene CG13000 16-Dec-15 2015_12 viable DRSC19519 I -0.128396254 -1.859094899 -0.943614089 0.242461374 0.01070667 0.643580336 FBgn0040850 CG15210 http://flybase.net/reports/FBgn0040850.html protein_coding_gene CG15210 16-Dec-15 2015_12 viable DRSC27768 K -0.269155104 0.119959772 0.225446542 0.477769682 2.063271969 0.325302084 FBgn0030731 Mfe2 peroxisomal Multifunctional enzyme type 2 http://flybase.net/reports/FBgn0030731.html protein_coding_gene "0080023=3R-hydroxyacyl-CoA dehydratase activity, 0016491=oxidoreductase activity, 0004300=enoyl-CoA hydratase activity, 0042803=protein homodimerization activity" "0008152=metabolic process, 0033540=fatty acid beta-oxidation using acyl-CoA oxidase" 0005777=peroxisome "Multifunctional enzyme type 2, CG3415, peroxisomal multifunctional enzyme type 2, MFE-2, DmMFE-2" "IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002539=MaoC-like domain, IPR029069=HotDog domain, IPR002347=Glucose/ribitol dehydrogenase" CG3415 16-Dec-15 2015_12 ENSDARG00000031873(hsd17b4) YKR009C(FOX2) WBGene00000991(dhs-28) ENSXETG00000017534(hsd17b4) ENSMUSG00000024507(Hsd17b4) ENSG00000133835(HSD17B4) viable FBgn0058032 CG40032 http://flybase.net/reports/FBgn0058032.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033072 CG17994 http://flybase.net/reports/FBgn0033072.html protein_coding_gene CG17994 16-Dec-15 2015_12 viable FBgn0000649 fdg fibrillar dysgenesis http://flybase.net/reports/FBgn0000649.html gene "l(1)fibrillardysgenesis, l(1)fdg" 16-Dec-15 2015_12 "lethal,heat sensitive" "muscle fiber,Z disc | embryonic stage" FBgn0262693 Su(VGlut)B12 http://flybase.net/reports/FBgn0262693.html gene B12 16-Dec-15 2015_12 FBgn0052264 CG32264 http://flybase.net/reports/FBgn0052264.html "FBgn0035456, FBgn0035457, FBgn0035459, FBgn0035460" protein_coding_gene "CG14978, CG10860, CG10857, CG12604" IPR004018=RPEL repeat CG32264 16-Dec-15 2015_12 "ENSDARG00000027172(phactr2),ENSDARG00000032221(phactr4)" WBGene00009174(F26H9.2) ENSXETG00000002268(PHACTR1) "ENSMUSG00000062866(Phactr2),ENSMUSG00000066043(Phactr4)" "ENSG00000112419(PHACTR2),ENSG00000204138(PHACTR4)" "viable,fertile" FBgn0016630 E(gl)2F Enhancer of glass 2F http://flybase.net/reports/FBgn0016630.html gene 16-Dec-15 2015_12 "lethal,recessive" rhabdomere FBgn0030274 Lint-1 l(3)mbt interacting protein 1 http://flybase.net/reports/FBgn0030274.html protein_coding_gene 0005700=polytene chromosome "CG1908, dLint-1" CG1908 16-Dec-15 2015_12 "viable,fertile" DRSC28176 IEK 2.902049034 -0.863166332 2.382078794 -1.335135865 -0.727501268 3.584519884 FBgn0020018 Ppox Protoporphyrinogen oxidase http://flybase.net/reports/FBgn0020018.html FBgn0046768 protein_coding_gene 0004729=oxygen-dependent protoporphyrinogen oxidase activity "0006783=heme biosynthetic process, 0055114=oxidation-reduction process" 0005743=mitochondrial inner membrane "protoporphyrinogen-oxidase, Protoporphyrinogen-oxidase, ESTS:9F2T, PPO, BcDNA:LD41392, CG5796" "IPR004572=Protoporphyrinogen oxidase, IPR002937=Amine oxidase, IPR027418=Protoporphyrinogen oxidase, C-terminal domain" CG5796 16-Dec-15 2015_12 ENSDARG00000025200 YER014W(HEM14) ENSXETG00000017673(PPOX) ENSMUSG00000062729(Ppox) ENSG00000143224(PPOX) "viable,lethal" DRSC17033 K 0.587372641 0.013652038 0.640129481 0.615431267 -1.612202663 0.462699958 FBgn0065762 l(2)SH0477 lethal (2) SH0477 http://flybase.net/reports/FBgn0065762.html gene l(2)SH2 0477 16-Dec-15 2015_12 "lethal,recessive" FBgn0004465 Su(P) Suppressor of ref(2)P sterility http://flybase.net/reports/FBgn0004465.html protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0009055=electron carrier activity" 0045454=cell redox homeostasis CG4086 "IPR004046=Glutathione S-transferase, C-terminal, IPR002109=Glutaredoxin, IPR011767=Glutaredoxin active site, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG4086 16-Dec-15 2015_12 ENSDARG00000068415(ptgesl) WBGene00011239(R11A8.5) ENSXETG00000012893(PTGES2) ENSMUSG00000026820(Ptges2) ENSG00000148334(PTGES2) "viable,fertile" FBgn0038649 CG7718 http://flybase.net/reports/FBgn0038649.html protein_coding_gene 0008444=CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity 0008654=phospholipid biosynthetic process PL D "IPR001736=Phospholipase D/Transphosphatidylase, IPR025202=Phospholipase D-like domain, IPR016270=Phospholipase D, phosphatidylserine synthase type" CG7718 16-Dec-15 2015_12 YCL004W(PGS1) WBGene00021677(pgs-1) ENSXETG00000009987(PGS1) ENSMUSG00000017715(Pgs1) ENSG00000087157(PGS1) "partially lethal - majority die,some die during pupal stage" FBgn0030562 CG9400 http://flybase.net/reports/FBgn0030562.html FBgn0044785 protein_coding_gene 0005576=extracellular region anon-WO0140519.10 "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG9400 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0032563 CG15258 http://flybase.net/reports/FBgn0032563.html protein_coding_gene CG15258 16-Dec-15 2015_12 viable FBgn0037829 CG14691 http://flybase.net/reports/FBgn0037829.html protein_coding_gene 0055085=transmembrane transport "0016021=integral component of membrane, 0008021=synaptic vesicle" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG14691 16-Dec-15 2015_12 viable FBgn0015467 l(2)44Fb lethal (2) 44Fb http://flybase.net/reports/FBgn0015467.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0260336 GSd433 http://flybase.net/reports/FBgn0260336.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0002280 l(3)73Ae lethal (3) 73Ae http://flybase.net/reports/FBgn0002280.html gene l(3)std18 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0023529 CG2918 http://flybase.net/reports/FBgn0023529.html protein_coding_gene "0006457=protein folding, 0032504=multicellular organism reproduction" "0005811=lipid particle, 0012505=endomembrane system, 0005615=extracellular space" "GRP170, CT9894, EG:25E8.1" "IPR013126=Heat shock protein 70 family, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR018181=Heat shock protein 70, conserved site, IPR029048=Heat shock protein 70kD, C-terminal domain" CG2918 16-Dec-15 2015_12 ENSDARG00000013670(hyou1) WBGene00011771(T14G8.3) ENSXETG00000010075(HYOU1) ENSMUSG00000032115(Hyou1) ENSG00000149428(HYOU1) lethal FBgn0030929 CG15043 http://flybase.net/reports/FBgn0030929.html FBgn0063022 protein_coding_gene BcDNA:RE41194 CG15043 16-Dec-15 2015_12 viable FBgn0053285 CG33285 http://flybase.net/reports/FBgn0053285.html "FBgn0045112, FBgn0045114" protein_coding_gene "NEST:bs33a04, NEST:bs33a07" CG33285 16-Dec-15 2015_12 FBgn0265490 BG01442 http://flybase.net/reports/FBgn0265490.html gene 16-Dec-15 2015_12 FBgn0039214 puf puffyeye http://flybase.net/reports/FBgn0039214.html "FBgn0045241, FBgn0064992" protein_coding_gene 0004843=ubiquitin-specific protease activity "0060968=regulation of gene silencing, 0035220=wing disc development, 0031647=regulation of protein stability, 0043687=post-translational protein modification, 0045824=negative regulation of innate immune response, 0002784=regulation of antimicrobial peptide production, 0030307=positive regulation of cell growth, 0045751=negative regulation of Toll signaling pathway, 0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 1900425=negative regulation of defense response to bacterium" 0005634=nucleus "Q9VC56, CG5794, BcDNA:AT28817, NEST:bs19d10, USP34, Usp34" "IPR011989=Armadillo-like helical, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain, IPR016024=Armadillo-type fold, IPR018200=Ubiquitin specific protease, conserved site" CG5794 16-Dec-15 2015_12 ENSXETG00000002218(USP34) ENSMUSG00000056342 ENSG00000115464(USP34) "some die during larval stage,some die during pupal stage,partially lethal - majority die,short lived,male sterile,size defective,viable,visible,lethal - all die before end of pupal stage,heat sensitive,decreased cell size,lethal - all die during pupal stage,increased cell death" "eye,ommatidium,wing,scutellar bristle,posterior,wing vein" FBgn0038528 CG14326 http://flybase.net/reports/FBgn0038528.html FBgn0047154 protein_coding_gene BcDNA:RE19820 CG14326 16-Dec-15 2015_12 viable FBgn0031746 CG9029 http://flybase.net/reports/FBgn0031746.html protein_coding_gene "0006952=defense response, 0032504=multicellular organism reproduction" 0005615=extracellular space CG9029 16-Dec-15 2015_12 viable FBgn0001869 l(1)XC78 lethal (1) XC78 http://flybase.net/reports/FBgn0001869.html gene 16-Dec-15 2015_12 FBgn0052088 sunn sisters unbound http://flybase.net/reports/FBgn0052088.html "FBgn0036200, FBtr0076116, FBpp0075847" protein_coding_gene "0051754=meiotic sister chromatid cohesion, centromeric" "0000775=chromosome, centromeric region" "CG32088, CG7308" CG32088 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0045862 btz barentsz http://flybase.net/reports/FBgn0045862.html "FBgn0016077, FBgn0039542" protein_coding_gene "0003723=RNA binding, 0031369=translation initiation factor binding" "0008380=RNA splicing, 0008103=oocyte microtubule cytoskeleton polarization, 0006397=mRNA processing, 0045450=bicoid mRNA localization, 0007318=pole plasm protein localization, 0045451=pole plasm oskar mRNA localization" "0005635=nuclear envelope, 0035145=exon-exon junction complex, 0005737=cytoplasm" "unnamed, wkl, Dm SELOR, Barentsz, barentz, CG12878, weak localizer, Btz" "IPR028544=Protein CASC3, IPR018545=Btz domain" CG12878 16-Dec-15 2015_12 ENSDARG00000029911(casc3) WBGene00012343(W08E3.2) ENSXETG00000024395(casc) ENSMUSG00000078676(Casc3) ENSG00000108349(CASC3) "wild-type,female sterile,cold sensitive,maternal effect,visible,partially lethal - majority die,some die during pupal stage" "pole cell,cold sensitive,ovary,ovariole,maternal effect,abdomen,embryonic abdominal segment,embryonic/first instar larval cuticle,denticle belt,microtubule & oocyte | oogenesis stage S9 | germ-line clone,trichogen cell,mesothoracic tergum" DRSC14566 I -1.690579569 -1.129018823 -0.172981651 1.078007625 0.037486648 -0.24751291 FBgn0065139 l(3)SH113 lethal (3) SH113 http://flybase.net/reports/FBgn0065139.html gene l(2)SH3 113 16-Dec-15 2015_12 "lethal,recessive" FBgn0265137 Spn42Da Serpin 42Da http://flybase.net/reports/FBgn0265137.html "FBgn0028985, FBgn0033111, FBgn0026360" protein_coding_gene "0004869=cysteine-type endopeptidase inhibitor activity, 0004867=serine-type endopeptidase inhibitor activity" "0030162=regulation of proteolysis, 0010955=negative regulation of protein processing, 0060570=negative regulation of peptide hormone processing, 0010951=negative regulation of endopeptidase activity" "0005576=extracellular region, 0005783=endoplasmic reticulum, 0005615=extracellular space" "neuroserpin, spn4, Spn4A, Spn4, sp4, Serp2, dSerp2, Serpin 4, Spn42Da, CG9453, Sp4, serpin 4, Serine protease inhibitor 4" "IPR023796=Serpin domain, IPR000215=Serpin family" CG9453 16-Dec-15 2015_12 ENSDARG00000034168(serpini1) "WBGene00005643(srp-2),WBGene00005648(srp-7),WBGene00005647(srp-6),WBGene00005644(srp-3),WBGene00005642(srp-1)" ENSXETG00000022866(SERPINI1) "ENSMUSG00000027834(Serpini1),ENSMUSG00000034139(Serpini2)" "ENSG00000163536(SERPINI1),ENSG00000114204(SERPINI2)" FBgn0030509 CG11162 http://flybase.net/reports/FBgn0030509.html protein_coding_gene "0000254=C-4 methylsterol oxidase activity, 0005506=iron ion binding" "0006633=fatty acid biosynthetic process, 0055114=oxidation-reduction process" IPR006694=Fatty acid hydroxylase CG11162 16-Dec-15 2015_12 YGR060W(ERG25) ENSMUSG00000031604(Sc4mol) viable FBgn0085605 CG41300 http://flybase.net/reports/FBgn0085605.html FBan0041300 protein_coding_gene 16-Dec-15 2015_12 FBgn0263486 scaRNA:ë¬U6-40 small Cajal body-specific RNA : ë¬U6-40 http://flybase.net/reports/FBgn0263486.html snoRNA_gene 0030565=snRNA pseudouridylation guide activity 0015030=Cajal body "snoRNA:skd-a, pugU6-40" CR43601 16-Dec-15 2015_12 FBgn0065615 l(2)SH0822 lethal (2) SH0822 http://flybase.net/reports/FBgn0065615.html gene l(2)SH2 0822 16-Dec-15 2015_12 "lethal,recessive" FBgn0020900 Su(osk)C37 Suppressor of oskar C37 http://flybase.net/reports/FBgn0020900.html gene C37 16-Dec-15 2015_12 FBgn0028352 l(1)G0166 lethal (1) G0166 http://flybase.net/reports/FBgn0028352.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014986 l(2)46Db lethal (2) 46Db http://flybase.net/reports/FBgn0014986.html gene "Group VIII, VIII" 16-Dec-15 2015_12 lethal FBgn0023050 l(1)3Am lethal (1) 3Am http://flybase.net/reports/FBgn0023050.html gene B2/45.10 16-Dec-15 2015_12 "lethal,recessive" FBgn0014352 ms(3)HB74 ms(3)HB74 http://flybase.net/reports/FBgn0014352.html gene 16-Dec-15 2015_12 FBgn0022973 snRNP200K snRNP200K http://flybase.net/reports/FBgn0022973.html gene "0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus" 200K/PRP8 16-Dec-15 2015_12 FBgn0025479 p35 p35 http://flybase.net/reports/FBgn0025479.html gene Dmp5 16-Dec-15 2015_12 FBgn0017462 TfIIH-97 Transcription factor IIH-97kD http://flybase.net/reports/FBgn0017462.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TfIIH, TFIIH" 16-Dec-15 2015_12 FBgn0065490 l(2)SH1237 lethal (2) SH1237 http://flybase.net/reports/FBgn0065490.html gene l(2)SH2 1237 16-Dec-15 2015_12 "lethal,recessive" FBgn0010465 l(2)00629 lethal (2) 00629 http://flybase.net/reports/FBgn0010465.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001547 l(1)16Fa lethal (1) 16Fa http://flybase.net/reports/FBgn0001547.html gene "I[[1]], MEI, ME-I" 16-Dec-15 2015_12 "lethal,non-rescuable maternal effect,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,polyphasic" "adult epidermis,somatic clone" FBgn0038426 mRpS33 mitochondrial ribosomal protein S33 http://flybase.net/reports/FBgn0038426.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "CG10406, MRP-S33" "IPR013219=Ribosomal protein S27/S33, mitochondrial" CG10406 16-Dec-15 2015_12 ENSDARG00000020015(mrps33) WBGene00009013(F21D5.8) ENSXETG00000004853(MRPS33) ENSMUSG00000029918(Mrps33) ENSG00000090263(MRPS33) "size defective,viable,visible" "adult heart,trichogen cell" FBgn0002207 l(3)67BDe lethal (3) 67BDe http://flybase.net/reports/FBgn0002207.html gene "l(3)e154A1, l(3)e49A4" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0024501 Acp31F Accessory gland protein 31F http://flybase.net/reports/FBgn0024501.html gene 16-Dec-15 2015_12 adult stage | male " male accessory gland main cell

, male accessory gland

" FBgn0085582 CR41257 http://flybase.net/reports/FBgn0085582.html FBan0041257 non_protein_coding_gene CG41257 CR41257 16-Dec-15 2015_12 FBgn0267363 JYalpha JYalpha http://flybase.net/reports/FBgn0267363.html "FBgn0040037, FBgn0085503, FBan0040625" protein_coding_gene "0005391=sodium:potassium-exchanging ATPase activity, 0005524=ATP binding, 0046872=metal ion binding" "0030317=sperm motility, 0006813=potassium ion transport, 0006812=cation transport, 0006814=sodium ion transport" "0005886=plasma membrane, 0016021=integral component of membrane, 0005890=sodium:potassium-exchanging ATPase complex" "CG17923, JYAlpha, CG40625, JY-alpha, CG45760" "IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR023214=HAD-like domain, IPR004014=Cation-transporting P-type ATPase, N-terminal, IPR006068=Cation-transporting P-type ATPase, C-terminal, IPR023299=P-type ATPase, cytoplasmic domain N, IPR005775=P-type ATPase, subfamily IIC, IPR001757=P-type ATPase, IPR023298=P-type ATPase, transmembrane domain" CG45760 16-Dec-15 2015_12 FBgn0003192 rab rabbit http://flybase.net/reports/FBgn0003192.html gene 16-Dec-15 2015_12 "viable,fertile,visible" "microchaeta,adult thorax,scutellum,wing" FBgn0082973 snoRNA:ë¬28S-3308 snoRNA:ë¬28S-3308 http://flybase.net/reports/FBgn0082973.html snoRNA_gene "Psi 28S-3308, chr3L:816004..816178, psi28s-3308, CR34632" CR34632 16-Dec-15 2015_12 FBgn0264665 stertorous stertorous http://flybase.net/reports/FBgn0264665.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "embryonic/larval tracheal system,eye,somatic clone" FBgn0263213 CR43383 http://flybase.net/reports/FBgn0263213.html pseudogene_attribute CR43383 16-Dec-15 2015_12 FBgn0013953 Esp Epidermal stripes and patches http://flybase.net/reports/FBgn0013953.html protein_coding_gene 0008271=secondary active sulfate transmembrane transporter activity "0008272=sulfate transport, 0055085=transmembrane transport, 0045434=negative regulation of female receptivity, post-mating" 0016021=integral component of membrane "epidermal stripes and patches, unnamed, CG7005" "IPR011547=SLC26A/SulP transporter domain, IPR001902=SLC26A/SulP transporter, IPR002645=STAS domain" CG7005 16-Dec-15 2015_12 "YLR092W(SUL2),YBR294W(SUL1)" ENSXETG00000019624(SLC26A11) "viable,fertile,partially lethal - majority die,some die during pupal stage,mating behavior defective,female limited,female semi-fertile" FBgn0036514 CG12301 http://flybase.net/reports/FBgn0036514.html protein_coding_gene "0022008=neurogenesis, 0006364=rRNA processing, 0009267=cellular response to starvation, 0016319=mushroom body development" 0032040=small-subunit processome "IPR006709=Small-subunit processome, Utp14" CG12301 16-Dec-15 2015_12 ENSDARG00000042520(si:dkey-251i10.3) YML093W(UTP14) WBGene00017855(F27C1.6) ENSXETG00000007465(Q66JC9_XENTR) "ENSMUSG00000063785(Utp14a),ENSMUSG00000079470(Utp14b)" "ENSG00000156697(UTP14A),ENSG00000214320" "neuroanatomy defective,lethal" "adult mushroom body,embryonic/larval neuroblast,ganglion mother cell" FBgn0004911 Eip63F-2 Ecdysone-induced protein 63F 2 http://flybase.net/reports/FBgn0004911.html FBgn0052265 non_protein_coding_gene "E63F, CG32265, Eip63Fb, E63-2, CR32265" CR32265 16-Dec-15 2015_12 " embryonic stage -- adult stage , larval stage " embryonic/larval salivary gland

FBgn0010702 l(2)s5211 lethal (2) s5211 http://flybase.net/reports/FBgn0010702.html gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0001177 hat half out http://flybase.net/reports/FBgn0001177.html gene l(3)84Ca 16-Dec-15 2015_12 "lethal,recessive" FBgn0266963 CR45414 http://flybase.net/reports/FBgn0266963.html non_protein_coding_gene CR45414 16-Dec-15 2015_12 FBgn0016040 mpl-2 male prothoracic leg 2 http://flybase.net/reports/FBgn0016040.html gene MPL-2 16-Dec-15 2015_12 FBgn0041837 Eth-AR206 Eth-AR206 http://flybase.net/reports/FBgn0041837.html gene Eth[AR]206 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0001697 l(1)ESHS18 lethal (1) ESHS18 http://flybase.net/reports/FBgn0001697.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024732 Drep1 DNA fragmentation factor-related protein 1 http://flybase.net/reports/FBgn0024732.html protein_coding_gene "0042981=regulation of apoptotic process, 0043066=negative regulation of apoptotic process, 0006309=apoptotic DNA fragmentation, 0045476=nurse cell apoptotic process" 0005622=intracellular "ICAD/DREP-1, Rep1, DREP-1/dICAD, Drep-1, Inhibitor of CAD, Drep1, dICAD, DFF45-related protein-1, ICAD, CG8357, DREP-1, drep1" "IPR003508=CIDE-N domain, IPR017299=DNA fragmentation factor subunit alpha" CG8357 16-Dec-15 2015_12 ENSDARG00000055770(dffa) ENSMUSG00000028974(Dffa) "viable,fertile,cell death defective,conditional" "ovary,chromatin | conditional,nurse cell,conditional,follicle cell,egg chamber" FBgn0000136 as ascute http://flybase.net/reports/FBgn0000136.html gene 16-Dec-15 2015_12 "visible,recessive" "scutellum,thorax,wing,eye" FBgn0060579 l(3)S095203b lethal (3) S095203b http://flybase.net/reports/FBgn0060579.html gene 0952/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0050320 CG30320 http://flybase.net/reports/FBgn0050320.html FBgn0064907 protein_coding_gene BcDNA:RE02263 16-Dec-15 2015_12 FBgn0035483 Mul1 Mitochondrial E3 ubiquitin protein ligase 1 homologue http://flybase.net/reports/FBgn0035483.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0090141=positive regulation of mitochondrial fission" "0031307=integral component of mitochondrial outer membrane, 0005777=peroxisome" "MUL1, CG1134" "IPR001841=Zinc finger, RING-type, IPR022170=Mitochondrial ubiquitin ligase activator of NFKB 1, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG1134 16-Dec-15 2015_12 "ENSDARG00000052527(mul1b),ENSDARG00000021398(mul1)" ENSXETG00000006837(MUL1) ENSMUSG00000041241(Mul1) ENSG00000090432(MUL1) "viable,fertile" FBgn0003947 Uf Unfolded http://flybase.net/reports/FBgn0003947.html gene 16-Dec-15 2015_12 "viable,fertile" wing FBgn0034335 GstE1 Glutathione S transferase E1 http://flybase.net/reports/FBgn0034335.html protein_coding_gene 0004364=glutathione transferase activity "0009408=response to heat, 0006749=glutathione metabolic process, 0006979=response to oxidative stress" 0005737=cytoplasm "gstE1, DmGSTE1, GSTE1, CG5164, gst-3, glutathione-S-transferase, glutathione-S-transferase E1, Gst55F, DmGSTE1-1, Gst3, Glutathione S-transferase, GST-3, GST3, Gst-theta 55F, CT16545, Gst-3, DmGST-3, GST-E1, gste1" "IPR004046=Glutathione S-transferase, C-terminal, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like" CG5164 16-Dec-15 2015_12 YLL060C(GTT2) " embryonic stage , embryonic stage -- adult stage , egg stage | unfertilized egg " "

ubiquitous , unfertilized egg | ubiquitous

" "lethal,viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0019800 l(1)05 lethal (1) 05 http://flybase.net/reports/FBgn0019800.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031444 CG9879 http://flybase.net/reports/FBgn0031444.html protein_coding_gene 0003677=DNA binding "0006352=DNA-templated transcription, initiation" "IPR012295=Beta2-adaptin/TBP, C-terminal domain, IPR000814=TATA-box binding protein" CG9879 16-Dec-15 2015_12 viable FBgn0265558 18.94 http://flybase.net/reports/FBgn0265558.html gene 16-Dec-15 2015_12 learning defective FBgn0039264 CG11786 http://flybase.net/reports/FBgn0039264.html protein_coding_gene CG11786 16-Dec-15 2015_12 FBgn0039396 CCAP-R Crustacean cardioactive peptide receptor http://flybase.net/reports/FBgn0039396.html "FBgn0039397, FBgn0046531, FBgn0046532, FBgn0053344" protein_coding_gene "0005000=vasopressin receptor activity, 0008188=neuropeptide receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway, 0018990=ecdysis, chitin-based cuticle" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "CG6111, CG14547, CCAP receptor, Cardioacceleratory peptide receptor, CG33344, anon-WO0170980.47, CCAP-R, Crustacean cardioactive peptide receptor, DCCAPR, CcapR, anon-WO0170980.46" "IPR001817=Vasopressin receptor, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG33344 16-Dec-15 2015_12 "ENSDARG00000044175(LOC100331744),ENSDARG00000033956(LOC100001530),ENSDARG00000045788(si:ch211-125a15.3),ENSDARG00000070520,ENSDARG00000029219,ENSDARG00000007436" "ENSXETG00000018781(AVPR1A),ENSXETG00000005930(AVPR1B),ENSXETG00000001441(OXTR),ENSXETG00000015741(),ENSXETG00000014233(AVPR2)" ENSMUSG00000043659(Npsr1) ENSG00000187258(NPSR1) " embryonic stage--larval stage , adult stage " head

viable FBgn0001047 fs(3)HO191 female sterile (3) HO191 http://flybase.net/reports/FBgn0001047.html gene fs(3)191A 16-Dec-15 2015_12 FBgn0261817 CG42759 http://flybase.net/reports/FBgn0261817.html protein_coding_gene CG42759 16-Dec-15 2015_12 FBgn0001172 Had ë_ Hydroxy acid dehydrogenase http://flybase.net/reports/FBgn0001172.html gene 0003973=(S)-2-hydroxy-acid oxidase activity HAD 16-Dec-15 2015_12 electrophoretic variant FBgn0050104 NT5E-2 Ecto-5'-nucleotidase 2 http://flybase.net/reports/FBgn0050104.html FBgn0034226 protein_coding_gene "0008253=5'-nucleotidase activity, 0000166=nucleotide binding, 0046872=metal ion binding" 0009166=nucleotide catabolic process "CG4837, CG30104" "IPR008334=5'-Nucleotidase, C-terminal, IPR006179=5'-Nucleotidase/apyrase, IPR006146=5'-Nucleotidase, conserved site, IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG30104 16-Dec-15 2015_12 ENSDARG00000071017(LOC100334175) ENSXETG00000018096(NT5E) ENSMUSG00000032420(Nt5e) ENSG00000135318(NT5E) "viable,fertile" FBgn0039487 gb genderblind http://flybase.net/reports/FBgn0039487.html FBgn0062114 protein_coding_gene 0015171=amino acid transmembrane transporter activity "0015734=taurine transport, 0007635=chemosensory behavior, 0042742=defense response to bacterium, 0006868=glutamine transport, 0008049=male courtship behavior, 0007619=courtship behavior, 0015813=L-glutamate transport, 0006909=phagocytosis, 0014047=glutamate secretion, 0003333=amino acid transmembrane transport" "0031594=neuromuscular junction, 0016020=membrane" "Genderblind, CG6070, Gb, anon-WO0118547.295" IPR002293=Amino acid/polyamine transporter I CG6070 16-Dec-15 2015_12 "ENSDARG00000055226(slc7a7),ENSDARG00000054423(slc7a6),ENSDARG00000020278(LOC566469)" "YGR055W(MUP1),YHL036W(MUP3)" WBGene00000003(aat-2) "neurophysiology defective,courtship behavior defective,male,immune response defective,short lived,conditional,smell perception defective,locomotor behavior defective,viable" "larval neuromuscular junction & postsynaptic membranetub.PU,larval neuromuscular junction & postsynaptic membrane,larval neuromuscular junction & postsynaptic membraneExel6206),embryonic/larval neuromuscular junction,larval neuromuscular junction & bouton" FBgn0083293 E(smoDN)2016 Enhancer of smoDN 2016 http://flybase.net/reports/FBgn0083293.html gene 16-Dec-15 2015_12 FBgn0040673 CG15234 http://flybase.net/reports/FBgn0040673.html FBgn0047219 protein_coding_gene BcDNA:LD10051 16-Dec-15 2015_12 viable FBgn0031216 Zir Zizimin-related http://flybase.net/reports/FBgn0031216.html FBgn0025528 protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0035010=encapsulation of foreign target, 0035011=melanotic encapsulation of foreign target, 0035023=regulation of Rho protein signal transduction, 0006909=phagocytosis" "Dm zir, CG11376, anon-EST:Posey54, FBgn 31216" "IPR027007=DHR-1 domain, IPR027357=DHR-2 domain, IPR010703=Dedicator of cytokinesis C-terminal, IPR021816=Dedicator of cytokinesis C/D, N-terminal, IPR026791=Dedicator of cytokinesis" CG11376 16-Dec-15 2015_12 "ENSDARG00000016072,ENSDARG00000035706,ENSDARG00000055225(dock8)" WBGene00018520(F46H5.4) ENSXETG00000001648(DOCK8) "ENSMUSG00000028556(Dock7),ENSMUSG00000032198(Dock6),ENSMUSG00000052085(Dock8)" "ENSG00000116641(DOCK7),ENSG00000130158(DOCK6),ENSG00000107099(DOCK8)" "immune response defective,recessive,viable" lamellocyte FBgn0035524 CG11583 http://flybase.net/reports/FBgn0035524.html FBgn0052253 protein_coding_gene 0019843=rRNA binding "0022008=neurogenesis, 0040018=positive regulation of multicellular organism growth, 0000027=ribosomal large subunit assembly" 0005730=nucleolus "CG32253, dBRX1" "IPR026532=Ribosome biogenesis protein BRX1, IPR007109=Brix domain, IPR004154=Anticodon-binding" CG11583 16-Dec-15 2015_12 ENSDARG00000024511(bxdc2) YOL077C(BRX1) WBGene00019678(K12H4.3) ENSXETG00000000703(BRIX1) ENSMUSG00000022247(Brix1) ENSG00000113460(BRIX1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0062637 EP950 EP950 http://flybase.net/reports/FBgn0062637.html gene 16-Dec-15 2015_12 FBgn0002070 l(2)49Dc lethal (2) 49Dc http://flybase.net/reports/FBgn0002070.html gene l(2)C 16-Dec-15 2015_12 "lethal,recessive,non-suppressor of variegation,dominant" FBgn0030665 CG15646 http://flybase.net/reports/FBgn0030665.html protein_coding_gene CG15646 16-Dec-15 2015_12 FBgn0037325 CG12147 http://flybase.net/reports/FBgn0037325.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0016055=Wnt signaling pathway, 0030177=positive regulation of Wnt signaling pathway" 0005737=cytoplasm "CKIalpha like, CKIa-like" "IPR011009=Protein kinase-like domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site" CG12147 16-Dec-15 2015_12 viable FBgn0262010 CG42828 http://flybase.net/reports/FBgn0262010.html "FBan0006784, FBgn0039074" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity CG6784 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42828 16-Dec-15 2015_12 "viable,fertile" FBgn0016943 strb starburst http://flybase.net/reports/FBgn0016943.html gene 16-Dec-15 2015_12 wing hair FBgn0267189 CR45629 http://flybase.net/reports/FBgn0267189.html non_protein_coding_gene CR45629 16-Dec-15 2015_12 FBgn0040033 CG15826 http://flybase.net/reports/FBgn0040033.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265901 CR44690 http://flybase.net/reports/FBgn0265901.html non_protein_coding_gene CR44690 16-Dec-15 2015_12 FBgn0000964 tj traffic jam http://flybase.net/reports/FBgn0000964.html "FBgn0020276, FBgn0032786" protein_coding_gene "0046982=protein heterodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity" "0007298=border follicle cell migration, 0008585=female gonad development, 0008584=male gonad development, 0035262=gonad morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0006351=transcription, DNA-templated, 0010467=gene expression" 0005634=nucleus "Traffic Jam, fs(2)eoPL3, TJ, DM13, maf1, Dmaf, maf-L, Traffic jam, female sterile(2)eo2, Traffic-Jam, fs(2)eo-B, Tj, fs(2)eo2, CG10034, PL3, Traffic-jam" "IPR004827=Basic-leucine zipper domain, IPR008917=Transcription factor, Skn-1-like, DNA-binding domain, IPR024874=Transcription factor Maf, IPR004826=Basic leucine zipper domain, Maf-type" CG10034 16-Dec-15 2015_12 "ENSDARG00000044155(mafl),ENSDARG00000051752,ENSDARG00000015890,ENSDARG00000017121(mafba)" "ENSXETG00000004936(mafa),ENSXETG00000000172(maf-2),ENSXETG00000019411(mafb),ENSXETG00000022130(maf)" "ENSMUSG00000055435(Maf),ENSMUSG00000047591(Mafa),ENSMUSG00000074622(Mafb)" "ENSG00000178573(MAF),ENSG00000204103(MAFB),ENSG00000182759(MAFA)" "developmental rate defective,female sterile,viable,recessive,sterile,male sterile" "border follicle cell,testis,ovary,testis & fusome,ovarian sheath,ectopic,terminal filament,somatic clone" FBgn0034346 CG12263 http://flybase.net/reports/FBgn0034346.html FBgn0044668 protein_coding_gene 0003824=catalytic activity 0008152=metabolic process anon-WO0140519.205 "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR002591=Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase, IPR017850=Alkaline-phosphatase-like, core domain" CG12263 16-Dec-15 2015_12 YLL031C(GPI13) WBGene00016159(C27A12.9) ENSXETG00000002364(PIGO) ENSMUSG00000028454(Pigo) ENSG00000165282(PIGO) "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0000112 ar abdomen rotatum http://flybase.net/reports/FBgn0000112.html gene 0007275=multicellular organismal development 16-Dec-15 2015_12 "male sterile,recessive,visible,viable,poor,fertile,female semi-sterile" "abdomen,male genitalia,puparium" FBgn0062561 P30 P30 http://flybase.net/reports/FBgn0062561.html gene 16-Dec-15 2015_12 FBgn0260720 CR42547 http://flybase.net/reports/FBgn0260720.html non_protein_coding_gene CR42547 16-Dec-15 2015_12 FBgn0005145 l(2)DTS8 lethal (2) DTS8 http://flybase.net/reports/FBgn0005145.html gene DTS-L8 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,recessive" FBgn0259105 dar7 dendritic arbor reduction 7 http://flybase.net/reports/FBgn0259105.html gene 0050775=positive regulation of dendrite morphogenesis 16-Dec-15 2015_12 FBgn0058406 CG40406 http://flybase.net/reports/FBgn0058406.html protein_coding_gene 16-Dec-15 2015_12 FBgn0262968 CR43279 http://flybase.net/reports/FBgn0262968.html non_protein_coding_gene lincRNA.961 CR43279 16-Dec-15 2015_12 FBgn0040992 CG10570 http://flybase.net/reports/FBgn0040992.html protein_coding_gene 0046331=lateral inhibition Dromel_CG10570_FBtr0081122_mORF CG10570 16-Dec-15 2015_12 "viable,visible" "chaeta,mesothoracic tergum" FBgn0024909 Taf7 TBP-associated factor 7 http://flybase.net/reports/FBgn0024909.html protein_coding_gene "0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0003700=sequence-specific DNA binding transcription factor activity" "0006367=transcription initiation from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" "0005634=nucleus, 0005669=transcription factor TFIID complex" "TAF7, TAF, TBP-associated factor 55kD, CG2670, E, TFIID, Taf55, TAF55, TAF[[II]], dTAF[[II]]55, anon-84Ec, TAF[[II]]55, unnamed, TBP-associated factor" "IPR006751=TAFII55 protein, conserved region" CG2670 16-Dec-15 2015_12 ENSDARG00000019572(taf7) YMR227C(TAF7) "ENSMUSG00000051316(Taf7),ENSMUSG00000074734,ENSMUSG00000009596(Taf7l)" "ENSG00000178913(TAF7),ENSG00000102387(TAF7L)" viable DRSC15445 K -1.420504708 0.186451639 -0.82137932 -0.171355117 1.66579907 2.55220475 FBgn0259727 CG42381 http://flybase.net/reports/FBgn0259727.html protein_coding_gene "Dromel_CG9865_FBtr0071680_cx9c_uorf1, CG9865(uORF1)" "IPR027179=Mature-T-Cell Proliferation I type, IPR009069=Cysteine alpha-hairpin motif superfamily" CG42381 16-Dec-15 2015_12 ENSMUSG00000079529 ENSG00000182712(MTCP1NB) FBgn0030357 Sclp Sclp http://flybase.net/reports/FBgn0030357.html protein_coding_gene 0003012=muscle system process "CT8171, CG2471, dSCLP" IPR001611=Leucine-rich repeat CG2471 16-Dec-15 2015_12 WBGene00010675(K08E7.8) ENSXETG00000025653(lrrc20) ENSMUSG00000037151(Lrrc20) ENSG00000172731(LRRC20) viable FBgn0034411 CG18605 http://flybase.net/reports/FBgn0034411.html protein_coding_gene CG18605 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" tormogen cell FBgn0060876 l(3)S045602 lethal (3) S045602 http://flybase.net/reports/FBgn0060876.html gene 0456/02 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266496 s-12 http://flybase.net/reports/FBgn0266496.html gene 16-Dec-15 2015_12 FBgn0262487 CG43077 http://flybase.net/reports/FBgn0262487.html protein_coding_gene CG43077 16-Dec-15 2015_12 FBgn0020859 cv-3 crossveinless 3 http://flybase.net/reports/FBgn0020859.html gene 0007474=imaginal disc-derived wing vein specification 16-Dec-15 2015_12 FBgn0267699 T:TM-Nrt membrane tethering sequence from Nrt http://flybase.net/reports/FBgn0267699.html engineered_tag 16-Dec-15 2015_12 FBgn0038691 CG5250 http://flybase.net/reports/FBgn0038691.html protein_coding_gene 0005391=sodium:potassium-exchanging ATPase activity "0006814=sodium ion transport, 0006813=potassium ion transport" 0005890=sodium:potassium-exchanging ATPase complex IPR000402=Sodium/potassium-transporting ATPase subunit beta CG5250 16-Dec-15 2015_12 viable FBgn0010488 NAT1 NAT1 http://flybase.net/reports/FBgn0010488.html FBgn0033780 protein_coding_gene 0003743=translation initiation factor activity "0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0022416=chaeta development, 0046331=lateral inhibition" 0005845=mRNA cap binding complex "CG3845, Nat1, dNAT1, l(2)01424, lethal (2) 01424" "IPR016024=Armadillo-type fold, IPR003891=Initiation factor eIF-4 gamma, MA3, IPR003307=W2 domain, IPR016021=MIF4G-like domain, IPR003890=MIF4G-like, type 3" CG3845 16-Dec-15 2015_12 "ENSDARG00000057167(eif4g2b),ENSDARG00000020377(eif4g2a)" ENSXETG00000013674(BC075569.1) ENSMUSG00000005610(Eif4g2) ENSG00000110321(EIF4G2) "viable,fertile,lethal,recessive,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0028382 cyp33 cyclophilin-33 http://flybase.net/reports/FBgn0028382.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003755=peptidyl-prolyl cis-trans isomerase activity, 0003723=RNA binding" "0006457=protein folding, 0000398=mRNA splicing, via spliceosome, 0006909=phagocytosis, 0000413=protein peptidyl-prolyl isomerization" "0005634=nucleus, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0000974=Prp19 complex" "CYP33, CG4886, Cyp33, Dcyp33" "IPR000504=RNA recognition motif domain, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR016304=Cyclophilin-type peptidyl-prolyl cis-trans isomerase E, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000=Cyclophilin-like domain" CG4886 16-Dec-15 2015_12 ENSDARG00000059270(ppie) WBGene00000889(cyn-13) ENSMUSG00000028651(Ppie) ENSG00000084072(PPIE) DRSC05666 E -0.455749141 0.52805237 -1.557667081 0.366418191 -0.546541561 1.278941332 FBgn0014067 Su(tor)3-337 Su(tor)3-337 http://flybase.net/reports/FBgn0014067.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003572 su(pd) suppressor of purpleoid http://flybase.net/reports/FBgn0003572.html gene 16-Dec-15 2015_12 FBgn0065185 l(2)SH2350 lethal (2) SH2350 http://flybase.net/reports/FBgn0065185.html gene l(2)SH2 2350 16-Dec-15 2015_12 "lethal,recessive" FBgn0060724 l(3)S068111b lethal (3) S068111b http://flybase.net/reports/FBgn0060724.html gene 0681/11 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085274 CG34245 http://flybase.net/reports/FBgn0085274.html protein_coding_gene CG34245 16-Dec-15 2015_12 FBgn0019792 l(1)11A lethal (1) 11A http://flybase.net/reports/FBgn0019792.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263447 CR43470 http://flybase.net/reports/FBgn0263447.html non_protein_coding_gene CR43470 16-Dec-15 2015_12 FBgn0265923 CR44712 http://flybase.net/reports/FBgn0265923.html non_protein_coding_gene lincRNA.1040 CR44712 16-Dec-15 2015_12 FBgn0261716 DJ913 http://flybase.net/reports/FBgn0261716.html gene 16-Dec-15 2015_12 chemical resistant FBgn0041136 l(2)44Ff lethal (2) 44Ff http://flybase.net/reports/FBgn0041136.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036226 CG7252 http://flybase.net/reports/FBgn0036226.html FBgn0047190 protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region BcDNA:LP01340 IPR002557=Chitin binding domain CG7252 16-Dec-15 2015_12 "WBGene00019833(R02F2.4),WBGene00015102(cpg-2)" viable DRSC21492 K -0.83438418 0.017571379 -0.75938183 0.500859948 1.543918243 -1.150629369 FBgn0013382 acj4 abnormal-chemosensory-jump-4 http://flybase.net/reports/FBgn0013382.html gene 0007636=chemosensory jump behavior 16-Dec-15 2015_12 "chemosensitive behavior defective,recessive" FBgn0011220 gor gorp http://flybase.net/reports/FBgn0011220.html gene 0007286=spermatid development 16-Dec-15 2015_12 male semi-sterile FBgn0265655 CR44462 http://flybase.net/reports/FBgn0265655.html non_protein_coding_gene lincRNA.310 CR44462 16-Dec-15 2015_12 FBgn0065500 l(2)SH1210 lethal (2) SH1210 http://flybase.net/reports/FBgn0065500.html gene l(2)SH2 1210 16-Dec-15 2015_12 "lethal,recessive" FBgn0027956 l(3)S148213 lethal (3) S148213 http://flybase.net/reports/FBgn0027956.html gene 1482/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0267439 CR45789 http://flybase.net/reports/FBgn0267439.html non_protein_coding_gene Mgn687 CR45789 16-Dec-15 2015_12 FBgn0031721 CG14017 http://flybase.net/reports/FBgn0031721.html protein_coding_gene IPR027887=Protein of unknown function DUF4464 CG14017 16-Dec-15 2015_12 ENSG00000197826(C4orf22) FBgn0065527 l(2)SH1117 lethal (2) SH1117 http://flybase.net/reports/FBgn0065527.html gene l(2)SH2 1117 16-Dec-15 2015_12 "lethal,recessive" FBgn0022942 Cbp80 cap binding protein 80 http://flybase.net/reports/FBgn0022942.html FBgn0025614 protein_coding_gene 0000339=RNA cap binding "0000398=mRNA splicing, via spliceosome, 0030422=production of siRNA involved in RNA interference, 0045292=mRNA cis splicing, via spliceosome, 0022008=neurogenesis, 0051028=mRNA transport, 0045071=negative regulation of viral genome replication, 0035195=gene silencing by miRNA" "0005846=nuclear cap binding complex, 0005634=nucleus, 0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "CBP80, EG:84H4.3, Cap-binding protein 80, cbp80, CG7035, Cap Binding Protein 80" "IPR027159=Nuclear cap-binding protein subunit 1, IPR016021=MIF4G-like domain, IPR003890=MIF4G-like, type 3, IPR015174=MIF4G-like, type 2, IPR015172=MIF4G-like, type 1, IPR016024=Armadillo-type fold" CG7035 16-Dec-15 2015_12 YMR125W(STO1) WBGene00018156(ncbp-1) ENSXETG00000010179(ncbp1) ENSMUSG00000028330(Ncbp1) ENSG00000136937(NCBP1) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" DRSC18450 I -1.825106617 0.10782246 -1.352524155 -0.831251279 -1.351898547 -1.352447638 FBgn0263748 CG43673 http://flybase.net/reports/FBgn0263748.html "FBan0033173, FBgn0053173, FBgn0030689" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region "CG8473, CG33173" IPR002557=Chitin binding domain CG43673 16-Dec-15 2015_12 FBgn0035246 CG13928 http://flybase.net/reports/FBgn0035246.html protein_coding_gene 0008270=zinc ion binding "IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR011011=Zinc finger, FYVE/PHD-type" CG13928 16-Dec-15 2015_12 "viable,fertile" FBgn0033397 Cyp4p3 Cyp4p3 http://flybase.net/reports/FBgn0033397.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "4p3, CG10843, cytochrome P450" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG10843 16-Dec-15 2015_12 YDR402C(DIT2) "partially lethal - majority die,some die during pupal stage" FBgn0085443 spri sprint http://flybase.net/reports/FBgn0085443.html "FBan0032680, FBgn0052680, FBgn0030211, FBgn0030212, FBgn0030213, FBgn0030214, FBgn0040944, FBgn0052674, FBgn0053175, FBgn0066810, FBgn0030216" protein_coding_gene "0017016=Ras GTPase binding, 0017112=Rab guanyl-nucleotide exchange factor activity, 0019901=protein kinase binding, 0005085=guanyl-nucleotide exchange factor activity, 0030971=receptor tyrosine kinase binding" "0048675=axon extension, 0032483=regulation of Rab protein signal transduction, 0006897=endocytosis, 0007165=signal transduction, 0007298=border follicle cell migration" "0030139=endocytic vesicle, 0005938=cell cortex" "CG15299, CG15298, anon-WO03040301.275, CG15301, sprint-b, CG12638, Rin1, CG15300, CG32674, Spri, Sprint, sprint-a, sprint, CG32680, CG15297, CG34414, CG33175" "IPR000159=Ras-associating (RA) domain, IPR000980=SH2 domain, IPR003123=VPS9 domain" CG34414 16-Dec-15 2015_12 WBGene00008183(tag-333) "ENSXETG00000009700(RIN2),ENSXETG00000010292(RIN3),ENSXETG00000020565(RIN1)" "ENSMUSG00000001768(Rin2),ENSMUSG00000044456(Rin3)" "ENSG00000132669(RIN2),ENSG00000100599(RIN3)" "viable,fertile" FBgn0020561 anon-VII-I8 anon-VII-I8 http://flybase.net/reports/FBgn0020561.html gene 16-Dec-15 2015_12 "Bolwig organ,Bolwig nerve" FBgn0031609 CG15443 http://flybase.net/reports/FBgn0031609.html protein_coding_gene 0046331=lateral inhibition "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG15443 16-Dec-15 2015_12 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0035845 CG13675 http://flybase.net/reports/FBgn0035845.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG13675 16-Dec-15 2015_12 FBgn0014117 anon-96Fa anon-96Fa http://flybase.net/reports/FBgn0014117.html gene G transcript 16-Dec-15 2015_12 " larval stage , adult stage " " eye-antennal disc

, adult head

" FBgn0014989 l(2)46De lethal (2) 46De http://flybase.net/reports/FBgn0014989.html gene "XI, Group XI" 16-Dec-15 2015_12 lethal FBgn0038090 CG10909 http://flybase.net/reports/FBgn0038090.html protein_coding_gene "0008168=methyltransferase activity, 0003723=RNA binding" "0008033=tRNA processing, 0006364=rRNA processing" 0030532=small nuclear ribonucleoprotein complex "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR000692=Fibrillarin" CG10909 16-Dec-15 2015_12 viable FBgn0082370 EP3269 EP3269 http://flybase.net/reports/FBgn0082370.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0259333 EP-405 http://flybase.net/reports/FBgn0259333.html gene 16-Dec-15 2015_12 visible "wing hair,wing,chaeta" FBgn0002512 l(3)Sp2 lethal (3) Sp2 http://flybase.net/reports/FBgn0002512.html gene 16-Dec-15 2015_12 lethal FBgn0011037 l(3)s3123 lethal (3) s3123 http://flybase.net/reports/FBgn0011037.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0063364 EP416 BEST:SD01859 http://flybase.net/reports/FBgn0063364.html gene "EP(3)0416, BEST:SD01859, SD01859" 16-Dec-15 2015_12 "germline cell,male" FBgn0038581 CG14314 http://flybase.net/reports/FBgn0038581.html protein_coding_gene "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG14314 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" viable FBgn0000745 fs(1)A273 female sterile (1) A273 http://flybase.net/reports/FBgn0000745.html gene 0048477=oogenesis "fs(1)M114, fs(1)K1075" 16-Dec-15 2015_12 "female sterile,recessive,female sterile soma-dependent" "dorsal appendage,egg,chorion" FBgn0027266 l(1)G0219 lethal (1) G0219 http://flybase.net/reports/FBgn0027266.html gene 16-Dec-15 2015_12 "lethal,recessive" adult abdomen FBgn0039543 CG12428 http://flybase.net/reports/FBgn0039543.html protein_coding_gene 0008458=carnitine O-octanoyltransferase activity 0006635=fatty acid beta-oxidation 0005777=peroxisome carnitine palmitoyltransferase IPR000542=Acyltransferase ChoActase/COT/CPT CG12428 16-Dec-15 2015_12 ENSDARG00000040352(crot) "WBGene00009622(F41E7.6),WBGene00011850(T20B3.1)" ENSMUSG00000003623(Crot) ENSG00000005469(CROT) FBgn0032967 CG1428 http://flybase.net/reports/FBgn0032967.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "gi20129693, gi19527787" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR017850=Alkaline-phosphatase-like, core domain, IPR004245=Protein of unknown function DUF229" CG1428 16-Dec-15 2015_12 FBgn0024562 l(3)L6241 lethal (3) L6241 http://flybase.net/reports/FBgn0024562.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266246 CR44941 http://flybase.net/reports/FBgn0266246.html non_protein_coding_gene lincRNA.757 CR44941 16-Dec-15 2015_12 FBgn0060617 l(3)S089303b lethal (3) S089303b http://flybase.net/reports/FBgn0060617.html gene 0893/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0027208 l(1)G0384 lethal (1) G0384 http://flybase.net/reports/FBgn0027208.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065409 l(2)SH1571 lethal (2) SH1571 http://flybase.net/reports/FBgn0065409.html gene l(2)SH2 1571 16-Dec-15 2015_12 "lethal,recessive" FBgn0267176 CR45616 http://flybase.net/reports/FBgn0267176.html non_protein_coding_gene CR45616 16-Dec-15 2015_12 FBgn0036132 CG18587 http://flybase.net/reports/FBgn0036132.html protein_coding_gene 16-Dec-15 2015_12 FBgn0020232 Antp::ro Antp::ro http://flybase.net/reports/FBgn0020232.html engineered_fusion_gene 16-Dec-15 2015_12 visible ommatidium FBgn0053060 CG33060 http://flybase.net/reports/FBgn0053060.html FBgn0036611 protein_coding_gene CG13057 IPR007858=Dpy-30 motif CG33060 16-Dec-15 2015_12 FBgn0261637 CG42720 http://flybase.net/reports/FBgn0261637.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060368 l(3)S138107 lethal (3) S138107 http://flybase.net/reports/FBgn0060368.html gene 1381/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0044516 ifm(2)RU664 indirect flight muscle (2) RU664 http://flybase.net/reports/FBgn0044516.html gene RU664 16-Dec-15 2015_12 "viable,visible,sterile,recessive,flight defective" "wing,indirect flight muscle" FBgn0038695 CG14280 http://flybase.net/reports/FBgn0038695.html protein_coding_gene IPR000859=CUB domain CG14280 16-Dec-15 2015_12 viable FBgn0011742 Arp2 Actin-related protein 2 http://flybase.net/reports/FBgn0011742.html protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005524=ATP binding, 0003779=actin binding" "0051489=regulation of filopodium assembly, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0072553=terminal button organization, 0007015=actin filament organization, 0008064=regulation of actin polymerization or depolymerization, 0000902=cell morphogenesis, 0007010=cytoskeleton organization, 0034314=Arp2/3 complex-mediated actin nucleation" "0015629=actin cytoskeleton, 0005884=actin filament, 0005885=Arp2/3 protein complex" "ARP2, Actin-related protein 14D, Arp2, ARP14D, CG9901, Arp14D, Actr14D, arp2, Actin-related protein 14 Da" "IPR027306=Actin-related protein 2, IPR004000=Actin family, IPR020902=Actin/actin-like conserved site" CG9901 16-Dec-15 2015_12 "ENSDARG00000070076(actr2b),ENSDARG00000052438(actr2),ENSDARG00000004658(zgc:101810)" YDL029W(ARP2) WBGene00000200(arx-2) ENSXETG00000014001(BC090611.1) ENSMUSG00000020152(Actr2) "ENSG00000138071(ACTR2),ENSG00000213985" " embryonic stage | stage >=9 , embryonic stage | stage 16 " " embryonic central nervous system | presumptive

, embryonic/larval proventriculus

, embryonic/larval hindgut

" "visible,somatic clone,somatic clone - Minute background,neuroanatomy defective,lethal,partially lethal - majority die" "microchaeta,dorsocentral bristle,eye,somatic clone,ommatidium,somatic clone - Minute background,lens,eye photoreceptor cell,eye disc,synapseC57,neuromuscular junctionC57,bouton,trichogen cell,supernumerary,tormogen cell,mesothoracic tergum,actin cytoskeletonHml.PG" DRSC19332 I -1.605137631 -1.471464785 -0.291184 -0.505553853 -0.185682894 -0.153769191 FBgn0016955 tilL touch insensitive larva L http://flybase.net/reports/FBgn0016955.html gene line 350 16-Dec-15 2015_12 "touch sensitivity defective,recessive,behavior defective" FBgn0266257 CR44952 http://flybase.net/reports/FBgn0266257.html non_protein_coding_gene lincRNA.882 CR44952 16-Dec-15 2015_12 FBgn0261735 EC2394 http://flybase.net/reports/FBgn0261735.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0052237 CG32237 http://flybase.net/reports/FBgn0052237.html "FBgn0035579, FBgn0035580, FBgn0063054" protein_coding_gene "BcDNA:RE17910, CG13703, CG13706" "IPR004019=YLP motif, IPR004011=GYR motif" CG32237 16-Dec-15 2015_12 viable FBgn0011146 l(1)Q222 lethal (1) Q222 http://flybase.net/reports/FBgn0011146.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0023447 dch dark chestnut http://flybase.net/reports/FBgn0023447.html gene 16-Dec-15 2015_12 visible pigment cell FBgn0015451 l(1)9Fk lethal (1) 9Fk http://flybase.net/reports/FBgn0015451.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022066 l(2)k08002 lethal (2) k08002 http://flybase.net/reports/FBgn0022066.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083974 CG34138 http://flybase.net/reports/FBgn0083974.html protein_coding_gene CG34138 16-Dec-15 2015_12 FBgn0005000 crs cru sterile http://flybase.net/reports/FBgn0005000.html gene 16-Dec-15 2015_12 male sterile FBgn0053730 snmRNA:430:CR33730 snmRNA:430:CR33730 http://flybase.net/reports/FBgn0053730.html non_protein_coding_gene CR33730 CR33730 16-Dec-15 2015_12 FBgn0012344 Dh44 Diuretic hormone 44 http://flybase.net/reports/FBgn0012344.html FBgn0037725 protein_coding_gene "0008613=diuretic hormone activity, 0001664=G-protein coupled receptor binding, 0005184=neuropeptide hormone activity, 0005179=hormone activity" "0007218=neuropeptide signaling pathway, 0045475=locomotor rhythm, 0009755=hormone-mediated signaling pathway, 0007589=body fluid secretion, 0007186=G-protein coupled receptor signaling pathway" "0005615=extracellular space, 0005576=extracellular region" "Drome-DH[[44]], Drm-DH, DH[[44]], drome-DH44, diuretic hormone, CG8348, Dh, Diuretic hormone, DH, DH 44, DH44, CRF, CRF-like peptide, diuretic hormone 44, Diuretic hormone 44, CRF-like diuretic hormone" "IPR018446=Corticotropin-releasing factor conserved site, IPR000187=Corticotropin-releasing factor" CG8348 16-Dec-15 2015_12 "locomotor rhythm defective,viable" FBgn0022269 l(2)k00302 lethal (2) k00302 http://flybase.net/reports/FBgn0022269.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065690 l(2)SH0644 lethal (2) SH0644 http://flybase.net/reports/FBgn0065690.html gene l(2)SH2 0644 16-Dec-15 2015_12 "lethal,recessive" FBgn0027544 CG2217 http://flybase.net/reports/FBgn0027544.html protein_coding_gene BcDNA:GH11688 CG2217 16-Dec-15 2015_12 viable FBgn0267975 vib vibrator http://flybase.net/reports/FBgn0267975.html "FBgn0262468, FBgn0260992, FBgn0026158, FBgn0038689, FBgn0044524, FBgn0046402, FBgn0046440, FBgn0046474, FBgn0083089, FBgn0011376, FBgn0011359, FBgn0011404, FBgn0024527, FBgn0028148, FBgn0028011, FBgn0028702" protein_coding_gene "0035091=phosphatidylinositol binding, 0005548=phospholipid transporter activity" "0033206=meiotic cytokinesis, 0007112=male meiosis cytokinesis, 0031566=actomyosin contractile ring maintenance, 0007111=meiosis II cytokinesis, 0000916=actomyosin contractile ring contraction, 0043147=meiotic spindle stabilization, 0006810=transport, 0007110=meiosis I cytokinesis, 0001700=embryonic development via the syncytial blastoderm, 0048137=spermatocyte division, 0000915=actomyosin contractile ring assembly" "0016006=Nebenkern, 0032154=cleavage furrow, 0005886=plasma membrane, 0005794=Golgi apparatus, 0070732=spindle envelope, 0031965=nuclear membrane" "anon-WO0172774.16, PITP-DM, lethal (3) S045002c, PITP, lethal (3) S110416, l(3)j4A3, l(3)j7A3, gio, l(3)j5A6, l(3)S110416, l(3)S045002c, Vib, anon-WO0172774.28, 1104/16, Vibrator, anon-WO0142479.3, l(3)j7C8, anon-WO0172774.12, lethal (3) j5A6, l(3)S045002, giotto, CG5269, 0450/02" "IPR001666=Phosphatidylinositol transfer protein, IPR023393=START-like domain" CG5269 16-Dec-15 2015_12 "ENSDARG00000039490(pitpna),ENSDARG00000036005(pitpnb),ENSDARG00000015310(pitpnbl),ENSDARG00000044091(LOC100333060)" WBGene00021854(Y54F10AR.1) "ENSXETG00000026298(pitpnb),ENSXETG00000002259(PITPNB)" "ENSMUSG00000050017(Pitpnb),ENSMUSG00000017781(Pitpna)" "ENSG00000180957(PITPNB),ENSG00000174238(PITPNA)" FBgn0004808 fs(2)ltoHL22 female sterile (2) ltoHL22 http://flybase.net/reports/FBgn0004808.html gene 0007304=chorion-containing eggshell formation HL22 16-Dec-15 2015_12 female sterile FBgn0005344 rstl roughestlike http://flybase.net/reports/FBgn0005344.html gene "lz-l, lozenge-like" 16-Dec-15 2015_12 "viable,reduced" eye FBgn0001118 gnd grounded http://flybase.net/reports/FBgn0001118.html gene 16-Dec-15 2015_12 "flightless,recessive" Z disc FBgn0027347 fra::robo1 fra::robo http://flybase.net/reports/FBgn0027347.html engineered_fusion_gene "Fra, Robo-DCC, fra::robo" 16-Dec-15 2015_12 "viable,fertile,neuroanatomy defective,lethal,partially" "commissure,RP3 motor neuron,transverse nerve,intersegmental nerve,cholinergic neuron,midline crossing tract | embryonic stage 16,longitudinal connective,axonelav.PLu,embryonic/larval somatic muscle,precursor" FBgn0065672 l(2)SH0680 lethal (2) SH0680 http://flybase.net/reports/FBgn0065672.html gene l(2)SH2 0680 16-Dec-15 2015_12 "lethal,recessive" FBgn0052160 CR32160 http://flybase.net/reports/FBgn0052160.html FBgn0061381 non_protein_coding_gene "CG32160, BcDNA:RH34065" CR32160 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0060524 l(3)S102012b lethal (3) S102012b http://flybase.net/reports/FBgn0060524.html gene 1020/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0083977 CG34141 http://flybase.net/reports/FBgn0083977.html protein_coding_gene CG34141 16-Dec-15 2015_12 FBgn0025876 opus\gag gag http://flybase.net/reports/FBgn0025876.html transposable_element_gene "yoyo\gag, yoyo\Gag, gag, ORF1" 16-Dec-15 2015_12 FBgn0266238 CR44933 http://flybase.net/reports/FBgn0266238.html non_protein_coding_gene lincRNA.702 CR44933 16-Dec-15 2015_12 FBgn0039890 CG2316 http://flybase.net/reports/FBgn0039890.html protein_coding_gene "0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005524=ATP binding" 0055085=transmembrane transport "0005778=peroxisomal membrane, 0043190=ATP-binding cassette (ABC) transporter complex" "IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG2316 16-Dec-15 2015_12 YPL147W(PXA1) WBGene00004061(pmp-4) ENSXETG00000007705() "ENSMUSG00000055782(Abcd2),ENSMUSG00000031378(Abcd1)" "ENSG00000173208(ABCD2),ENSG00000101986(ABCD1)" "viable,fertile" FBgn0065249 l(2)SH2135 lethal (2) SH2135 http://flybase.net/reports/FBgn0065249.html gene l(2)SH2 2135 16-Dec-15 2015_12 "lethal,recessive" FBgn0034923 Upf3 Upf3 http://flybase.net/reports/FBgn0034923.html protein_coding_gene 0000166=nucleotide binding "0016246=RNA interference, 0035195=gene silencing by miRNA, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" "UPF3, CG11184, upf3" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR005120=Regulator of nonsense-mediated decay, UPF3" CG11184 16-Dec-15 2015_12 "ENSDARG00000000489(upf3b),ENSDARG00000069297(upf3a)" WBGene00004882(smg-4) "ENSXETG00000007440(UPF3B),ENSXETG00000002572(UPF3A)" "ENSMUSG00000038398(Upf3a),ENSMUSG00000036572(Upf3b)" "ENSG00000125351(UPF3B),ENSG00000169062(UPF3A)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0014020 Rho1 Rho1 http://flybase.net/reports/FBgn0014020.html "FBgn0014021, FBgn0024874, FBgn0024880" protein_coding_gene "0003924=GTPase activity, 0019900=kinase binding, 0005515=protein binding, 0005525=GTP binding" "0007391=dorsal closure, 0071896=protein localization to adherens junction, 0007010=cytoskeleton organization, 1901739=regulation of myoblast fusion, 0007480=imaginal disc-derived leg morphogenesis, 0006897=endocytosis, 0030589=pseudocleavage involved in syncytial blastoderm formation, 0016203=muscle attachment, 0090254=cell elongation involved in imaginal disc-derived wing morphogenesis, 0048813=dendrite morphogenesis, 0010004=gastrulation involving germ band extension, 0035147=branch fusion, open tracheal system, 0031532=actin cytoskeleton reorganization, 0035159=regulation of tube length, open tracheal system, 0042249=establishment of planar polarity of embryonic epithelium, 0007422=peripheral nervous system development, 0016055=Wnt signaling pathway, 0030950=establishment or maintenance of actin cytoskeleton polarity, 0035006=melanization defense response, 0042060=wound healing, 0034613=cellular protein localization, 0007405=neuroblast proliferation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity, 0050770=regulation of axonogenesis, 0000281=mitotic cytokinesis, 0090251=protein localization involved in establishment of planar polarity, 0007298=border follicle cell migration, 0046664=dorsal closure, amnioserosa morphology change, 0007173=epidermal growth factor receptor signaling pathway, 0016318=ommatidial rotation, 0007349=cellularization, 0008354=germ cell migration, 0030036=actin cytoskeleton organization, 0006974=cellular response to DNA damage stimulus, 1903475=mitotic actomyosin contractile ring assembly, 0016476=regulation of embryonic cell shape, 0030239=myofibril assembly, 0051493=regulation of cytoskeleton organization, 0008045=motor neuron axon guidance, 0007015=actin filament organization, 0007424=open tracheal system development, 0007254=JNK cascade, 0007368=determination of left/right symmetry, 0035099=hemocyte migration, 0070593=dendrite self-avoidance, 0007395=dorsal closure, spreading of leading edge cells, 0007411=axon guidance, 0035298=regulation of Malpighian tubule size, 0090090=negative regulation of canonical Wnt signaling pathway, 0001745=compound eye morphogenesis, 0090303=positive regulation of wound healing, 0008347=glial cell migration, 0046663=dorsal closure, leading edge cell differentiation, 0007374=posterior midgut invagination, 0030866=cortical actin cytoskeleton organization, 0051489=regulation of filopodium assembly, 0007435=salivary gland morphogenesis, 0007370=ventral furrow formation, 0007369=gastrulation, 0007164=establishment of tissue polarity, 0035277=spiracle morphogenesis, open tracheal system, 0007377=germ-band extension, 0051017=actin filament bundle assembly, 0035149=lumen formation, open tracheal system, 0070252=actin-mediated cell contraction, 0007264=small GTPase mediated signal transduction, 0035317=imaginal disc-derived wing hair organization, 0045184=establishment of protein localization, 0045199=maintenance of epithelial cell apical/basal polarity, 0030334=regulation of cell migration" "0045179=apical cortex, 0005737=cytoplasm, 0044291=cell-cell contact zone, 0016324=apical plasma membrane, 0070451=cell hair, 0005886=plasma membrane, 0005938=cell cortex" "D-Rho1, dRho1, Rho A, RHO, RhoA kinase, dRhoA, RHO1, l(2)52Fa, DmRHO-A, 19549712, Dm Rho1, rho kinase, E3.10/J3.8, RhoA, rho1, 8416, DRho, dnRho, CG8416, RhoN19, Drho1, Rho, n(2)k07236, P48148, l(2)k02107b, rhoA, Rho GTPase, DrhoA, DRhoA, Rho kinase, AAF01186, rho1 kinase, DRho1, rho" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain" CG8416 16-Dec-15 2015_12 "ENSDARG00000015429(rhoac),ENSDARG00000026845(rhoaa),ENSDARG00000018328(rhoad),ENSDARG00000055766(rhoab),ENSDARG00000021309(rhoae)" YPR165W(RHO1) WBGene00004357(rho-1) "ENSXETG00000006898(TEgg047m10.1),ENSXETG00000005934(rhoa),ENSXETG00000009241(TNeu034e06.1)" "ENSMUSG00000007815(Rhoa),ENSMUSG00000002233(Rhoc)" ENSG00000067560(RHOA) " embryonic stage , embryonic stage -- adult stage , adult stage | female , pupal stage , P-stage " "

ubiquitous , organism

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,visible,some die during embryonic stage,planar polarity defective,somatic clone,cytokinesis defective,mitotic cell cycle defective,wound healing defective,non-suppressor of variegation,non-enhancer of variegation,maternal effect,cell shape defective,increased cell death,cell migration defective,conditional,phototaxis defective,chemical resistant,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" "adherens junction | pupal stageGMR.PF,eye | pupal stage,epithelial cell | pupal stage,hub cell,somatic clone,adherens junction | somatic clone,retina,eye,vacuoleGMR.PF,peripheral glial cell,presumptive embryonic salivary gland,embryonic hemocyte,filzkorper,circular visceral muscle primordium,cortical actin cytoskeleton & spiracular chamber,secondary pigment cell,tertiary pigment cell,photoreceptor cell,rhabdomere,ommatidium,pigment cell,interommatidial bristle,eye photoreceptor cell,morphogenetic furrow,wing hair,extended germ band embryo,embryonic/first instar larval cuticle,anterior,mushroom body & neuron | somatic clone,mushroom body & dendrite | somatic clone,dorsal closure embryo,embryonic epidermis,dorsal,embryonic dorsal epidermis,head,embryonic leading edge cell,embryo,embryonic head,embryonic/larval cuticle,ventral,abdominal ventral denticle belt,adult mushroom body,filopodium,embryonic/larval posterior spiracle,embryonic/larval dorsal trunk,mitotic telophase,mitotic telophase & spindle,actomyosin contractile ring,maternal effect,oocyte,nurse cell ring canal,denticle belt,leg,RP3 motor neuron,embryonic/first instar larval cuticle & embryonic head,embryonic segment,wing,supernumerary,tracheal primordium,presumptive embryonic/larval tracheal system,ommatidial precursor cluster,embryonic/larval trachea,filopodiumen-e16E,mesectoderm,ventral furrow,stomodeal invagination,amnioproctodeal invagination,anterior midgut primordium,mesoderm,embryonic Malpighian tubule tip cell,presumptive embryonic/larval muscle system,ventral longitudinal muscle,dorsal trunk primordium,imaginal disc | third instar larval stage,germline cell,ectopic,germline cell | embryonic stage,external sensory organ precursor cell,embryonic/larval midgut primordium,embryonic hindgut,embryonic/larval hindgut,cortical actin cytoskeleton & embryonic posterior spiracleems.HRE,primordium of embryonic/larval spiracle,posterior spiracle primordium,heat sensitive,border follicle cell,eye photoreceptor cell | third instar larval stage,lamina | third instar larval stage,filopodiumsrp.Hemo,embryonic/larval hemocyte | third instar larval stage,wing disc,disc epithelium proper & dorsal mesothoracic discptc-559.1,wing disc | third instar larval stage,wing blade,eye disc & photoreceptor cell & axonGMR.PF,Bolwig nerve,eye disc & subretinal glial cellGMR.PF,vertical lobe of adult mushroom body,peripheral glial cell | embryonic stage,sensory neuron & axonrepo,lateral trunk primordium,embryonic/larval dorsal anastomosis,mushroom body & dendriteTab2-201Y,mushroom body & dendrite | somatic cloneTab2-201Y,conditional | third instar larval stage,embryonic/larval hemolymph | third instar larval stage,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,anterior embryonic/larval midgut,vacuoleAppl.G1a,blastoderm embryo,germline clone,actin cytoskeleton | blastoderm stage | germline clone,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,actin filament & embryonic/larval tracheal systembtl.PS,adult cuticle,adult abdomen" DRSC07530 IE -1.087312644 -1.935045606 -0.616335897 -1.676516344 -0.002646985 -0.002958944 FBgn0034756 Cyp6d2 Cyp6d2 http://flybase.net/reports/FBgn0034756.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 1901563=response to camptothecin" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "6d2, cytochrome P450, CG4373" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG4373 16-Dec-15 2015_12 "ENSDARG00000037874(LOC558473),ENSDARG00000037873(cyp3c1l2),ENSDARG00000070021(zgc:153269),ENSDARG00000015575(cyp3c1)" YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "chemical sensitive,viable" FBgn0031220 CG4822 http://flybase.net/reports/FBgn0031220.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0043190=ATP-binding cassette (ABC) transporter complex "IPR003439=ABC transporter-like, IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain" CG4822 16-Dec-15 2015_12 "viable,lethal" FBgn0001666 l(1)EN1 lethal (1) from Eugene Nonautonomous 1 http://flybase.net/reports/FBgn0001666.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval salivary gland,gastric caecum,fat body" FBgn0036742 CG7497 http://flybase.net/reports/FBgn0036742.html "FBgn0046500, FBgn0046501, FBgn0046783" protein_coding_gene 0004930=G-protein coupled receptor activity "0007015=actin filament organization, 0007186=G-protein coupled receptor signaling pathway, 0008360=regulation of cell shape" 0016021=integral component of membrane "anon-WO0170980.88, anon-WO0170980.89, BcDNA:GH27361, CHED-related" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM, IPR008365=Prostanoid receptor" CG7497 16-Dec-15 2015_12 "ENSDARG00000011434,ENSDARG00000037033(si:ch211-13n20.1),ENSDARG00000038278,ENSDARG00000035415(ptger4b),ENSDARG00000059236(ptger4a),ENSDARG00000055781(LOC100000544)" "ENSMUSG00000071489(Ptgdr),ENSMUSG00000037759(Ptger2),ENSMUSG00000043017(Ptgir),ENSMUSG00000039942(Ptger4),ENSMUSG00000040016(Ptger3)" "ENSG00000168229(PTGDR),ENSG00000125384(PTGER2),ENSG00000160013(PTGIR),ENSG00000171522(PTGER4),ENSG00000050628(PTGER3),ENSG00000006638(TBXA2R)" "partially lethal - majority die,visible" trichogen cell FBgn0031322 CG5001 http://flybase.net/reports/FBgn0031322.html protein_coding_gene 0051082=unfolded protein binding "0009408=response to heat, 0006457=protein folding" "IPR018253=DnaJ domain, conserved site, IPR008971=HSP40/DnaJ peptide-binding, IPR002939=Chaperone DnaJ, C-terminal, IPR001623=DnaJ domain" CG5001 16-Dec-15 2015_12 "ENSDARG00000041394(dnajb1b),ENSDARG00000015831(dnajb1a),ENSDARG00000052881(LOC569466)" YNL007C(SIS1) WBGene00001031(dnj-13) "ENSXETG00000020601(dnajb4),ENSXETG00000013144(DNAJB4),ENSXETG00000014155(DNAJB5)" "ENSMUSG00000036052(Dnajb5),ENSMUSG00000028035(Dnajb4),ENSMUSG00000005483(Dnajb1)" "ENSG00000137094(DNAJB5),ENSG00000162616(DNAJB4),ENSG00000132002(DNAJB1)" "viable,fertile" DRSC26191 K -0.324679816 0.289097165 0.201279652 -0.285264351 -0.623457305 -2.252401078 FBgn0052105 CG32105 http://flybase.net/reports/FBgn0052105.html "FBgn0036275, FBgn0036276" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG10432, CG17615" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain, IPR001781=Zinc finger, LIM-type" CG32105 16-Dec-15 2015_12 YDL106C(PHO2) "ENSXETG00000013183(LMX1A),ENSXETG00000000641()" ENSMUSG00000026686(Lmx1a) "ENSG00000162761(LMX1A),ENSG00000136944(LMX1B)" FBgn0040666 CG12848 http://flybase.net/reports/FBgn0040666.html protein_coding_gene "IPR010625=CHCH, IPR009069=Cysteine alpha-hairpin motif superfamily" CG12848 16-Dec-15 2015_12 ENSDARG00000029100(chchd1) WBGene00016057(C24D10.6) ENSXETG00000010005(chchd1) ENSMUSG00000063787(Chchd1) ENSG00000172586(CHCHD1) "partially lethal - majority die,visible" "chaeta,supernumerary" FBgn0036142 CG7616 http://flybase.net/reports/FBgn0036142.html protein_coding_gene 0004672=protein kinase activity FBgn 36142 "IPR004147=UbiB domain, IPR011009=Protein kinase-like domain" CG7616 16-Dec-15 2015_12 ENSMUSG00000022550(Adck5) ENSG00000173137(ADCK5) viable FBgn0028605 l(2)W2 lethal (2) W2 http://flybase.net/reports/FBgn0028605.html gene l(2R)W2 16-Dec-15 2015_12 "lethal,recessive" FBgn0031774 CG9147 http://flybase.net/reports/FBgn0031774.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR016039=Thiolase-like, IPR008554=Glutaredoxin-like, IPR012336=Thioredoxin-like fold" CG9147 16-Dec-15 2015_12 "viable,fertile,visible" trichogen cell FBgn0003746 tre triangle eye http://flybase.net/reports/FBgn0003746.html gene 16-Dec-15 2015_12 "female sterile,viable,male fertile,visible" "wing,eye" FBgn0266022 CR44787 http://flybase.net/reports/FBgn0266022.html non_protein_coding_gene lincRNA.12 CR44787 16-Dec-15 2015_12 FBgn0026397 Or22b Odorant receptor 22b http://flybase.net/reports/FBgn0026397.html protein_coding_gene "0004984=olfactory receptor activity, 0004888=transmembrane signaling receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0030425=dendrite, 0016021=integral component of membrane, 0032590=dendrite membrane" "dor67, DOR22A.2, Odorant receptor 67, 22A.2, or22b, OR22b, 22b, Or67, Or22a/b, CG4231, Or22A.2, Dmel Or22b, AN12, DOR67, Dor67, dOr22b, Olfactory receptor 22A.2, DOR22b" "IPR004117=Olfactory receptor, Drosophila" CG4231 16-Dec-15 2015_12 adult stage sensory neuron &&of antennal segment 3

FBgn0040758 CG13166 http://flybase.net/reports/FBgn0040758.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035217 FucTD FucTD http://flybase.net/reports/FBgn0035217.html protein_coding_gene 0046920=alpha-(1->3)-fucosyltransferase activity 0006486=protein glycosylation 0016020=membrane CG9169 IPR001503=Glycosyl transferase family 10 CG9169 16-Dec-15 2015_12 viable FBgn0005590 scw screw http://flybase.net/reports/FBgn0005590.html "FBgn0002053, FBgn0003343, FBgn0046219, FBgn0051695" protein_coding_gene "0005160=transforming growth factor beta receptor binding, 0008083=growth factor activity, 0046982=protein heterodimerization activity" "0001708=cell fate specification, 0040007=growth, 0007378=amnioserosa formation, 0010629=negative regulation of gene expression, 0007179=transforming growth factor beta receptor signaling pathway, 0007502=digestive tract mesoderm development, 0007354=zygotic determination of anterior/posterior axis, embryo, 0030509=BMP signaling pathway, 0009953=dorsal/ventral pattern formation, 0008406=gonad development" "0005615=extracellular space, 0005576=extracellular region" "Screw, CG31695, SCW, mor2, l(2)IG76, l(2)37Ff, Scw, morphological defects 2, BcDNA:LD30945" "IPR015615=Transforming growth factor-beta-related, IPR029034=Cystine-knot cytokine, IPR001111=Transforming growth factor-beta, N-terminal, IPR017948=Transforming growth factor beta, conserved site, IPR001839=Transforming growth factor-beta, C-terminal" CG31695 16-Dec-15 2015_12 " embryonic stage , embryonic stage | 2-4 hr , embryonic stage | stage 4 " "wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,visible,partially lethal - majority die,some die during pupal stage,circadian rhythm defective,heat sensitive" "gonad,visceral mesoderm,crystal cell,embryonic leading edge cell,embryo,dorsal,cephalic furrow,embryonic/larval spiracle,posterior,denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,filzkorper,amnioserosa,embryonic/larval dorsal vessel,cephalopharyngeal skeleton,abdomen,extended germ band embryo,dorsal ectoderm,stage 14 embryo,embryonic/larval posterior spiracle,wing vein,ectopic,wing,compartment,distal" FBgn0004011 wgv wing variance http://flybase.net/reports/FBgn0004011.html gene 16-Dec-15 2015_12 "visible,male sterile,viable,male" wing FBgn0004440 prd5 paired-like 5 http://flybase.net/reports/FBgn0004440.html gene PRD gene 5 16-Dec-15 2015_12 embryonic stage | early FBgn0032067 LManIV Lysosomal ë±-mannosidase IV http://flybase.net/reports/FBgn0032067.html protein_coding_gene "0030246=carbohydrate binding, 0008270=zinc ion binding, 0004559=alpha-mannosidase activity" 0006013=mannose metabolic process 0005764=lysosome "LManIV, CG9465" "IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR015341=Glycoside hydrolase, family 38, central domain, IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR011013=Galactose mutarotase-like domain, IPR000602=Glycoside hydrolase family 38, N-terminal domain" CG9465 16-Dec-15 2015_12 WBGene00018877(aman-1) ENSXETG00000011609(MAN2B2) FBgn0277418 l(3)psg28 http://flybase.net/reports/FBgn0277418.html gene psg28 16-Dec-15 2015_12 FBgn0067332 su(Hw)BR-y-AS-C suppressor of Hairy wing Binding Region in the yellow achaete-scute region http://flybase.net/reports/FBgn0067332.html insulator "1A-2, 1A2, unnamed" 16-Dec-15 2015_12 FBgn0260943 Rbp6 RNA-binding protein 6 http://flybase.net/reports/FBgn0260943.html "FBgn0010260, FBgn0052169, FBgn0036699, FBgn0036700, FBgn0036701, FBgn0063045" protein_coding_gene "0008266=poly(U) RNA binding, 0000166=nucleotide binding, 0003727=single-stranded RNA binding, 0003729=mRNA binding" 0048864=stem cell development "0005844=polysome, 0005737=cytoplasm" "CG6573, RRM6, rbp6, CG14056, rrm6, CG32169, CG14055, BcDNA:RE25373" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG32169 16-Dec-15 2015_12 "ENSDARG00000031809(LOC100147844),ENSDARG00000058818(rbm38)" YOL123W(HRP1) FBgn0266617 CR45124 http://flybase.net/reports/FBgn0266617.html non_protein_coding_gene CR45124 16-Dec-15 2015_12 FBgn0004498 fs(1)ë_b4 female sterile (1) ë_b4 http://flybase.net/reports/FBgn0004498.html gene 16-Dec-15 2015_12 FBgn0005454 l(1)v361 lethal (1) v361 http://flybase.net/reports/FBgn0005454.html gene l(1)361 16-Dec-15 2015_12 FBgn0030425 CG3775 http://flybase.net/reports/FBgn0030425.html FBgn0043832 protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "zinc metalloprotease, BEST:GH06882" "IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13, IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain" CG3775 16-Dec-15 2015_12 DRSC19877 E -1.088592964 -1.224050489 -2.377314715 -2.825609375 0.242347627 0.695108768 FBgn0053987 CR33987 http://flybase.net/reports/FBgn0053987.html non_protein_coding_gene CR33987 16-Dec-15 2015_12 FBgn0051580 tRNA:CR31580 transfer RNA:CR31580 http://flybase.net/reports/FBgn0051580.html FBgn0060281 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3R.trna50-AlaAGC, CR31580, tRNA[[Ala]], AE002708.trna44-AlaAGC, tRNA:A:AGC:AE002708-h" CR31580 16-Dec-15 2015_12 FBgn0005325 NX Notch Xasta http://flybase.net/reports/FBgn0005325.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040129 l(2)22Aj lethal (2) 22Aj http://flybase.net/reports/FBgn0040129.html gene E 16-Dec-15 2015_12 "lethal,recessive" FBgn0070019 BG01046 BG01046 http://flybase.net/reports/FBgn0070019.html gene 0002121=inter-male aggressive behavior 16-Dec-15 2015_12 "stress response defective,behavior defective,recessive" FBgn0044126 E(rst)B246 E(rst)B246 http://flybase.net/reports/FBgn0044126.html gene 0001745=compound eye morphogenesis B246 16-Dec-15 2015_12 viable FBgn0036553 CG17027 http://flybase.net/reports/FBgn0036553.html protein_coding_gene 0008934=inositol monophosphate 1-phosphatase activity "0046855=inositol phosphate dephosphorylation, 0016311=dephosphorylation, 0046854=phosphatidylinositol phosphorylation" 0005737=cytoplasm "IMP, 152392_at" "IPR020550=Inositol monophosphatase, conserved site, IPR000760=Inositol monophosphatase, IPR020552=Inositol monophosphatase, Lithium-sensitive, IPR020583=Inositol monophosphatase, metal-binding site" CG17027 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0002452 l(3)SG5 lethal (3) SG5 http://flybase.net/reports/FBgn0002452.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0265187 CG44252 http://flybase.net/reports/FBgn0265187.html FBgn0050194 protein_coding_gene "0031957=very long-chain fatty acid-CoA ligase activity, 0015245=fatty acid transporter activity" "0008152=metabolic process, 0015908=fatty acid transport" 0016021=integral component of membrane CG30194 "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG44252 16-Dec-15 2015_12 "viable,fertile" FBgn0001445 l(1)7Cg lethal (1) 7Cg http://flybase.net/reports/FBgn0001445.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0060425 l(3)S126711 lethal (3) S126711 http://flybase.net/reports/FBgn0060425.html gene 1267/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0040192 l(1)G0185 lethal (1) G0185 http://flybase.net/reports/FBgn0040192.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260105 2L4771 http://flybase.net/reports/FBgn0260105.html gene 16-Dec-15 2015_12 "tracheal fusion cell,somatic clone,embryonic/larval dorsal trunk" FBgn0265794 CR44583 http://flybase.net/reports/FBgn0265794.html non_protein_coding_gene lincRNA.105 CR44583 16-Dec-15 2015_12 FBgn0032618 CG31743 http://flybase.net/reports/FBgn0032618.html FBgn0051743 protein_coding_gene 0008146=sulfotransferase activity 0016051=carbohydrate biosynthetic process 0016021=integral component of membrane "CG4826, 152851_at, dC4ST" "IPR005331=Sulfotransferase, IPR018011=Carbohydrate sulfotransferase-related" CG31743 16-Dec-15 2015_12 "ENSDARG00000004018,ENSDARG00000034375(chst11)" "ENSXETG00000004792(chst11),ENSXETG00000001882(CHST11),ENSXETG00000020585(chst12),ENSXETG00000027548(CHST8)" "ENSMUSG00000034612(Chst11),ENSMUSG00000060402(Chst8),ENSMUSG00000036599(Chst12)" "ENSG00000180767(CHST13),ENSG00000171310(CHST11)" FBgn0060755 l(3)SzB72Ca lethal (3) SzB72Ca http://flybase.net/reports/FBgn0060755.html gene "0643/01, l(3)S064301a" 16-Dec-15 2015_12 "lethal,recessive" FBgn0263959 BG01540 http://flybase.net/reports/FBgn0263959.html gene 16-Dec-15 2015_12 "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,male limited" FBgn0001553 l(1)19Ac lethal (1) 19Ac http://flybase.net/reports/FBgn0001553.html gene "l(1)EM19, EM19" 16-Dec-15 2015_12 lethal FBgn0040260 Ugt36Bc Ugt36Bc http://flybase.net/reports/FBgn0040260.html FBgn0032606 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG17932, AC 005121C" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG17932 16-Dec-15 2015_12 "WBGene00011006(ugt-47),WBGene00011564(ugt-50),WBGene00015141(ugt-46),WBGene00015965(ugt-48),WBGene00007070(ugt-49)" viable FBgn0267355 3L-079 http://flybase.net/reports/FBgn0267355.html nuclear_gene Gene_3L_079 16-Dec-15 2015_12 FBgn0027619 Adam Adam http://flybase.net/reports/FBgn0027619.html "FBgn0015482, FBgn0019724, FBgn0021866, FBgn0033470" protein_coding_gene 0003743=translation initiation factor activity "0006413=translational initiation, 0022008=neurogenesis" 0005852=eukaryotic translation initiation factor 3 complex "CG12131, E, l(2)46Cf, eIF3j, unnamed, 5.3, l(2)k13906, l(2)46CFd, Complementation group E, eIF3-S1, Q7K550_DROME" "IPR013906=Eukaryotic translation initiation factor 3 subunit J, IPR023194=Eukaryotic translation initiation factor 3-like domain" CG12131 16-Dec-15 2015_12 "ENSDARG00000012603(eif3ja),ENSDARG00000053370(eif3jb)" ENSXETG00000007840(eif3s1) "ENSMUSG00000027236(Eif3j),ENSMUSG00000043424(Gm9781)" ENSG00000104131(EIF3J) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0032665 CG15152 http://flybase.net/reports/FBgn0032665.html protein_coding_gene CG15152 16-Dec-15 2015_12 viable DRSC02453 K 0.024429725 0.104622304 -0.131175012 0.404384924 2.023839882 0.561828373 FBgn0267685 CR46021 http://flybase.net/reports/FBgn0267685.html non_protein_coding_gene CR46021 16-Dec-15 2015_12 FBgn0065828 l(2)SH0355 lethal (2) SH0355 http://flybase.net/reports/FBgn0065828.html gene l(2)SH2 0355 16-Dec-15 2015_12 "lethal,recessive" FBgn0013660 ms(2)neo5 ms(2)neo5 http://flybase.net/reports/FBgn0013660.html gene unnamed 16-Dec-15 2015_12 male sterile FBgn0262475 bru-2 bruno-2 http://flybase.net/reports/FBgn0262475.html "FBgn0043904, FBgn0032423, FBgn0051761, FBgn0051763" protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding, 0000166=nucleotide binding" 0017148=negative regulation of translation "CG6319, Dm Bru-2, CG31763, CG43065, bruno-2, bruno2, CG17008, CG31761, Bru-2" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG43065 16-Dec-15 2015_12 YCL011C(GBP2) WBGene00001340(etr-1) "ENSXETG00000020486(CELF4),ENSXETG00000014344(CELF5)" """DRSC01247, DRSC01246"" " IEK FBgn0263398 CG6364 http://flybase.net/reports/FBgn0263398.html "FBgn0262147, FBgn0039179" protein_coding_gene "0004849=uridine kinase activity, 0005524=ATP binding" "0006909=phagocytosis, 0008152=metabolic process" "CR42873, Uck2" "IPR006083=Phosphoribulokinase/uridine kinase, IPR000764=Uridine kinase-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6364 16-Dec-15 2015_12 "ENSDARG00000006074(uck2a),ENSDARG00000022213(uck2b),ENSDARG00000022218(uck1)" WBGene00007089(B0001.4) ENSXETG00000001482(UCK1) "ENSMUSG00000026558(Uck2),ENSMUSG00000002550(Uck1)" "ENSG00000143179(UCK2),ENSG00000130717(UCK1)" FBgn0259598 B0469 http://flybase.net/reports/FBgn0259598.html gene 16-Dec-15 2015_12 "visible,sterile" "submarginal cell,wing cell,tarsal segment,antennal segment,wing" FBgn0019728 l(2)148 lethal (2) 148 http://flybase.net/reports/FBgn0019728.html gene 16-Dec-15 2015_12 lethal FBgn0033874 CG6347 http://flybase.net/reports/FBgn0033874.html protein_coding_gene "0008234=cysteine-type peptidase activity, 0004197=cysteine-type endopeptidase activity" 0006508=proteolysis "IPR013201=Cathepsin propeptide inhibitor domain (I29), IPR025660=Cysteine peptidase, histidine active site, IPR013128=Peptidase C1A, IPR000668=Peptidase C1A, papain C-terminal" CG6347 16-Dec-15 2015_12 "viable,fertile" FBgn0265299 CR44272 http://flybase.net/reports/FBgn0265299.html non_protein_coding_gene CR44272 16-Dec-15 2015_12 FBgn0085426 Rgk3 "Rad, Gem/Kir family member 3" http://flybase.net/reports/FBgn0085426.html "FBan0015664, FBan0015663, FBgn0053949, FBgn0034610, FBgn0034609, FBgn0034608" protein_coding_gene 0005525=GTP binding "0007264=small GTPase mediated signal transduction, 1901386=negative regulation of voltage-gated calcium channel activity, 0015031=protein transport" 0016020=membrane "CG15660, CG15663, RGK3, Rgk3, CG34397, mdcds_15683, CG33949, mdcds_15673, CG15664" "IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type, IPR020849=Small GTPase superfamily, Ras type" CG34397 16-Dec-15 2015_12 "ENSMUSG00000031880(Rrad),ENSMUSG00000028214(Gem),ENSMUSG00000000359(Rem1),ENSMUSG00000022176(Rem2)" ENSG00000088320(REM1) viable FBgn0003680 ted trapped http://flybase.net/reports/FBgn0003680.html gene l(3)84Cf 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0086667 snoRNA:ë¬28S-3342 snoRNA:ë¬28S-3342 http://flybase.net/reports/FBgn0086667.html "FBgn0065061, FBgn0082964, FBgn0053787" snoRNA_gene 0005730=nucleolus "CR33787, psi28s-3342, Dm-644, snoRNA:644, Psi28S-3342(SnoR644), snoR644" CR33787 16-Dec-15 2015_12 FBgn0262321 mir-960 mir-960 stem loop http://flybase.net/reports/FBgn0262321.html miRNA_gene "0060259=regulation of feeding behavior, 0006955=immune response" "CR43028, miR-960, dme-mir-960, 960" CR43028 16-Dec-15 2015_12 visible FBgn0069910 CR41100 http://flybase.net/reports/FBgn0069910.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0263560 mir-4987 mir-4987 stem loop http://flybase.net/reports/FBgn0263560.html miRNA_gene "CR43545, dme-mir-4987" CR43545 16-Dec-15 2015_12 FBgn0033999 CG8093 http://flybase.net/reports/FBgn0033999.html protein_coding_gene "0016298=lipase activity, 0004806=triglyceride lipase activity" "0006629=lipid metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "Triglyceride lipase, CT22063" "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG8093 16-Dec-15 2015_12 ENSDARG00000018529(lipf) YKL140W(TGL1) "WBGene00021963(Y57E12B.3),WBGene00010062(F54F3.3),WBGene00020016(R11G11.14),WBGene00022642(ZK6.7),WBGene00009773(F46B6.8)" ENSXETG00000009273(lipA) "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" viable FBgn0260635 Diap1 Death-associated inhibitor of apoptosis 1 http://flybase.net/reports/FBgn0260635.html "FBgn0016903, FBgn0003691, FBgn0011383, FBgn0015246, FBgn0046835, FBgn0046836" protein_coding_gene "0005515=protein binding, 0031625=ubiquitin protein ligase binding, 1990381=ubiquitin-specific protease binding, 0008270=zinc ion binding, 0043027=cysteine-type endopeptidase inhibitor activity involved in apoptotic process, 0044390=ubiquitin-like protein conjugating enzyme binding, 0061663=NEDD8 ligase activity, 0004869=cysteine-type endopeptidase inhibitor activity, 0061630=ubiquitin protein ligase activity, 0031624=ubiquitin conjugating enzyme binding, 0089720=caspase binding" "0007289=spermatid nucleus differentiation, 0007298=border follicle cell migration, 0008354=germ cell migration, 0007275=multicellular organismal development, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 1990001=inhibition of cysteine-type endopeptidase activity involved in apoptotic process, 0070936=protein K48-linked ubiquitination, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0051865=protein autoubiquitination, 0000209=protein polyubiquitination, 0045116=protein neddylation, 0043154=negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, 0097340=inhibition of cysteine-type endopeptidase activity, 0048800=antennal morphogenesis, 0006915=apoptotic process, 0031398=positive regulation of protein ubiquitination, 2001271=negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis, 0007283=spermatogenesis, 0043066=negative regulation of apoptotic process, 0007423=sensory organ development, 0090263=positive regulation of canonical Wnt signaling pathway, 0045035=sensory organ precursor cell division, 0008407=chaeta morphogenesis" "0005634=nucleus, 0005737=cytoplasm" "inhibitor of apoptosis-1, diap1/thread, Drosophila inhibitor of apoptosis protein, E(rpr)3-1, Diap, degradation of inhibitors of apoptosis, diap, Inhibitor of Apoptosis Protein 1, dIAP-1, Drosophila Inhibitor of Apoptosis Protein-1, Iap1, Drosophila inhibitor of apoptosis, 1065/03, DIAP, inhibitor of apoptosis protein 1, TH, S048915, Drosophila inhibitor of apoptosis 1, diap-1, DIAPI, l(3)72CDe, Drosophila inhibitor of apoptosis protein 1, D-IAP1, DIAP-1, 0736/01, DIAP I, dIAP1, diap 1, l(3)j5C8, inhibitor of apoptotic protein 1, Drosophila Inhibitor of Apoptosis 1, CG12284, l(3)S030605, D-iap1, Drosophila thread/inhibitor of apoptosis protein-1, dIap1, l(3)72Dc, IAP1, Inhibitor of Apoptosis 1, Diap-1/Th, th, Drosophila Inhibitor of apoptosis protein 1, Thread, Drosophila IAP1, inhibitor of apoptosis, Diap-1, Drosophila Inhibitor of Apoptosis Protein, Diap1, thread, IAP, Drosophila Inhibitor of Apoptosis, Inhibitors of Apoptosis protein, l(3)S106503, DIAP1, dIAP, l(3)S030605b, Inhibitor of apoptosis 1, drosophila inhibitor of apoptosis protein, Drosophila Inhibitor of Apoptosis Protein 1, Drosophila inhibitor-of-apoptosis protein 1, diap1, lethal (3) 72CDe" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR001370=BIR repeat" CG12284 16-Dec-15 2015_12 WBGene00000250(bir-2) " embryonic stage , larval stage " "

ubiquitous , eye-antennal disc

" DRSC11404 IEK -0.43920138 -6.221428133 -2.699430873 -3.810293217 -0.584042549 16.1093693 FBgn0046647 anon-38D.2 anon-38D.2 http://flybase.net/reports/FBgn0046647.html gene 38D.2 16-Dec-15 2015_12 FBgn0260995 dpr21 defective proboscis extension response 21 http://flybase.net/reports/FBgn0260995.html protein_coding_gene "CG42596, Dpr21" "IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013106=Immunoglobulin V-set domain" CG42596 16-Dec-15 2015_12 FBgn0039104 CG10252 http://flybase.net/reports/FBgn0039104.html "FBgn0044748, FBgn0046295" protein_coding_gene 0016272=prefoldin complex "BEST:GH13953, bs30h03.y1, anon-WO0140519.133" IPR010736=Sperm-tail PG-rich repeat CG10252 16-Dec-15 2015_12 "ENSDARG00000014209(zgc:110183),ENSDARG00000021432(zgc:194430),ENSDARG00000042391(odf3l)" "ENSXETG00000006568(ODF3L2),ENSXETG00000015719(odf3)" "ENSMUSG00000035963(Odf3l2),ENSMUSG00000045620(Odf3l1),ENSMUSG00000025482(Odf3),ENSMUSG00000047394(Odf3b)" "ENSG00000181781(ODF3L2),ENSG00000182950(ODF3L1),ENSG00000177947(ODF3)" viable FBgn0036135 mRpL2 mitochondrial ribosomal protein L2 http://flybase.net/reports/FBgn0036135.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "L2, CG7636" "IPR008991=Translation protein SH3-like domain, IPR022666=Ribosomal Proteins L2, RNA binding domain, IPR022669=Ribosomal protein L2, C-terminal, IPR012340=Nucleic acid-binding, OB-fold, IPR014722=Ribosomal protein L2 domain 2, IPR002171=Ribosomal protein L2" CG7636 16-Dec-15 2015_12 ENSDARG00000062568 WBGene00018932(F56B3.8) ENSMUSG00000002767(Mrpl2) ENSG00000112651(MRPL2) "viable,visible" trichogen cell FBgn0065305 l(2)SH1971 lethal (2) SH1971 http://flybase.net/reports/FBgn0065305.html gene l(2)SH2 1971 16-Dec-15 2015_12 "lethal,recessive" FBgn0014936 anon-92Eb anon-92Eb http://flybase.net/reports/FBgn0014936.html gene sue 16-Dec-15 2015_12 FBgn0264870 CR44061 http://flybase.net/reports/FBgn0264870.html non_protein_coding_gene CR44061 16-Dec-15 2015_12 FBgn0011201 LysA Lysozyme A http://flybase.net/reports/FBgn0011201.html gene 0003796=lysozyme activity "IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain, IPR000974=Glycoside hydrolase, family 22, lysozyme, IPR019799=Glycoside hydrolase, family 22, conserved site" 16-Dec-15 2015_12 adult stage && larval stage FBgn0011174 l(1)291-44 lethal (1) 291-44 http://flybase.net/reports/FBgn0011174.html FBgn0010199 gene 291-44 16-Dec-15 2015_12 "lethal,recessive" FBgn0261582 CG42692 http://flybase.net/reports/FBgn0261582.html protein_coding_gene CG42692 16-Dec-15 2015_12 FBgn0033703 CG13170 http://flybase.net/reports/FBgn0033703.html protein_coding_gene CG13170 16-Dec-15 2015_12 viable DRSC06298 IE -1.582520474 -2.163717116 -0.840088367 -3.940983292 0.11281163 -1.008063469 FBgn0014886 Su(phl)43B Suppressor of pole hole 43B http://flybase.net/reports/FBgn0014886.html gene "Su(D-raf)43B, Suppressor of raf-like-oncogene" 16-Dec-15 2015_12 FBgn0031512 CG15404 http://flybase.net/reports/FBgn0031512.html protein_coding_gene CG15404 16-Dec-15 2015_12 viable FBgn0083083 l(2)49Fn l(2)49Fn http://flybase.net/reports/FBgn0083083.html gene 16-Dec-15 2015_12 "lethal,recessive,visible" wing FBgn0001898 l(2)21Fd lethal (2) 21Fd http://flybase.net/reports/FBgn0001898.html gene "l(2)neh12, l(2)neh-12" 16-Dec-15 2015_12 lethal FBgn0069920 CG41131 http://flybase.net/reports/FBgn0069920.html protein_coding_gene 16-Dec-15 2015_12 FBgn0063127 pncr002:3R putative noncoding RNA 002:3R http://flybase.net/reports/FBgn0063127.html FBgn0053938 non_protein_coding_gene "BcDNA:LP03188, CR33938" CR33938 16-Dec-15 2015_12 FBgn0085639 CG41389 http://flybase.net/reports/FBgn0085639.html FBan0041389 protein_coding_gene 16-Dec-15 2015_12 "ENSXETG00000008712(),ENSXETG00000011963(),ENSXETG00000022898(),ENSXETG00000014719(),ENSXETG00000004685(),ENSXETG00000024139()" FBgn0027539 CG5807 http://flybase.net/reports/FBgn0027539.html FBgn0062072 protein_coding_gene "anon-WO0118547.355, BcDNA:GH12663" "IPR008075=Lipocalin-1 receptor, IPR006876=LMBR1-like membrane protein" CG5807 16-Dec-15 2015_12 "ENSDARG00000024092(LOC557300),ENSDARG00000004745(lmbr1l)" WBGene00019877(R05D3.2) "ENSXETG00000011184(limr),ENSXETG00000013512(BC084916.1)" "ENSMUSG00000022999(Lmbr1l),ENSMUSG00000010721(Lmbr1)" "ENSG00000139636(LMBR1L),ENSG00000105983(LMBR1)" "viable,fertile" "germline cell,male" FBgn0083249 E(smoDN)O Enhancer of smoDN group O http://flybase.net/reports/FBgn0083249.html gene 0007224=smoothened signaling pathway Group O 16-Dec-15 2015_12 "lethal,recessive" FBgn0039488 CG6066 http://flybase.net/reports/FBgn0039488.html protein_coding_gene "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" 0071013=catalytic step 2 spliceosome IPR009269=Protein of unknown function DUF926 CG6066 16-Dec-15 2015_12 ENSDARG00000033450(zgc:136458) WBGene00017086(E01A2.4) ENSXETG00000007439(Q6GL16_XENTR) "ENSMUSG00000016409(Nkap),ENSMUSG00000059395(Nkapl)" "ENSG00000101882(NKAP),ENSG00000189134(NKAPL)" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female fertile,female sterile" "embryonic/larval neuroblast,ganglion mother cell" FBgn0267868 CR46156 http://flybase.net/reports/FBgn0267868.html non_protein_coding_gene CR46156 16-Dec-15 2015_12 FBgn0259603 B0519 http://flybase.net/reports/FBgn0259603.html gene 16-Dec-15 2015_12 visible wing FBgn0265840 CR44629 http://flybase.net/reports/FBgn0265840.html non_protein_coding_gene CR44629 16-Dec-15 2015_12 FBgn0024206 ol2 oocyte localisation 2 http://flybase.net/reports/FBgn0024206.html gene 16-Dec-15 2015_12 FBgn0069319 X-179-36 X-179-36 http://flybase.net/reports/FBgn0069319.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect" FBgn0036842 CG3797 http://flybase.net/reports/FBgn0036842.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG3797 16-Dec-15 2015_12 "WBGene00010904(ugt-62),WBGene00018206(ugt-61)" FBgn0034027 CG8187 http://flybase.net/reports/FBgn0034027.html protein_coding_gene IPR025164=Putative adhesin CG8187 16-Dec-15 2015_12 ENSDARG00000019142(LOC100332968) ENSXETG00000019736(FAM185A) ENSMUSG00000047221(Fam185a) "ENSG00000214439,ENSG00000222011(FAM185A)" viable FBgn0015695 E(cactE10)11 "Enhancer of cactusE10, number 11" http://flybase.net/reports/FBgn0015695.html gene unnamed 16-Dec-15 2015_12 FBgn0044445 EP912 EP912 http://flybase.net/reports/FBgn0044445.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0267679 CR46015 http://flybase.net/reports/FBgn0267679.html non_protein_coding_gene CR46015 16-Dec-15 2015_12 FBgn0051093 CG31093 http://flybase.net/reports/FBgn0051093.html "FBgn0039372, FBgn0063697" protein_coding_gene "BcDNA:AT30660, CG4964" CG31093 16-Dec-15 2015_12 FBgn0013480 l(1)1PP18 lethal (1) 1PP18 http://flybase.net/reports/FBgn0013480.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,rescuable maternal effect" "dorsal closure embryo,germline clone" FBgn0266037 CR44802 http://flybase.net/reports/FBgn0266037.html non_protein_coding_gene lincRNA.87 CR44802 16-Dec-15 2015_12 FBgn0058133 CG40133 http://flybase.net/reports/FBgn0058133.html FBan0040133 protein_coding_gene 16-Dec-15 2015_12 FBgn0020815 l(3)L0839 lethal (3) L0839 http://flybase.net/reports/FBgn0020815.html gene 16-Dec-15 2015_12 lethal FBgn0260662 U5-116k http://flybase.net/reports/FBgn0260662.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263108 BtbVII BTB-protein-VII http://flybase.net/reports/FBgn0263108.html "FBgn0012049, FBgn0035403, FBgn0062503" protein_coding_gene 0003677=DNA binding "CG11494, CG14956, BTB-VII, BcDNA:GH07729, BTBVII, CG43365, BTB protein VII" "IPR007889=DNA binding HTH domain, Psq-type, IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR009057=Homeodomain-like" CG43365 16-Dec-15 2015_12 ENSXETG00000000723(NACC2) ENSG00000160877(NACC1) DRSC08151 E -0.397614564 -1.031585472 1.589887515 -0.743215106 0.34181364 -0.218373287 FBgn0020884 Thin-wing Thin-wing http://flybase.net/reports/FBgn0020884.html gene Tn 16-Dec-15 2015_12 "visible,viable,fertile" wing FBgn0039741 CG7943 http://flybase.net/reports/FBgn0039741.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG7943 16-Dec-15 2015_12 "ENSDARG00000056163(zgc:73228),ENSDARG00000040463(LOC556422)" WBGene00011858(T20D3.5) ENSXETG00000018131(MCART6) ENSMUSG00000045973(Mcart1) "ENSG00000141437(MCART2),ENSG00000122696(MCART1)" viable FBgn0028184 l(3)S024120 lethal (3) S024120 http://flybase.net/reports/FBgn0028184.html gene 0241/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0264515 CR43914 http://flybase.net/reports/FBgn0264515.html non_protein_coding_gene "lincRNA.536, CG43914" CR43914 16-Dec-15 2015_12 FBgn0082334 HM786 HM786 http://flybase.net/reports/FBgn0082334.html gene 16-Dec-15 2015_12 FBgn0030544 CG13403 http://flybase.net/reports/FBgn0030544.html protein_coding_gene CG13403 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC19535 K 0.639832224 0.172376131 0.436685363 0.403573265 0.5687291 1.552636706 FBgn0001507 l(1)10Fa lethal (1) 10Fa http://flybase.net/reports/FBgn0001507.html FBgn0001618 gene "6, l(1)L6" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266903 CR45363 http://flybase.net/reports/FBgn0266903.html non_protein_coding_gene CR45363 16-Dec-15 2015_12 FBgn0033989 CG7639 http://flybase.net/reports/FBgn0033989.html protein_coding_gene 0019867=outer membrane IPR000184=Bacterial surface antigen (D15) CG7639 16-Dec-15 2015_12 "ENSDARG00000045814(samm50),ENSDARG00000039681(samm50l)" WBGene00001662(gop-3) ENSMUSG00000022437(Samm50) ENSG00000100347(SAMM50) "viable,visible" trichogen cell FBgn0067663 poached poached http://flybase.net/reports/FBgn0067663.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0040672 CG12476 http://flybase.net/reports/FBgn0040672.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065674 l(2)SH0677 lethal (2) SH0677 http://flybase.net/reports/FBgn0065674.html gene l(2)SH2 0677 16-Dec-15 2015_12 "lethal,recessive" FBgn0011361 ND-ACP NADH dehydrogenase (ubiquinone) acyl carrier protein http://flybase.net/reports/FBgn0011361.html FBgn0017568 protein_coding_gene "0031177=phosphopantetheine binding, 0000036=ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process" "0006120=mitochondrial electron transport, NADH to ubiquinone, 0006633=fatty acid biosynthetic process" 0005739=mitochondrion "NADH ubiquinone oxidoreductase ACP, mitochondrial acyl carrier protein of electron transport complex I, mitochondrial acyl carrier protein 1, NADH ubiquinone oxidoreductase acyl carrier protein, mitochondrial acyl carrier protein, mtacp1, ND-AcC, l(3)1303, CG9160, mtACP1, Acyl carrier protein, ACPM, NADH:ubiquinone oxidoreductase Acyl carrier, Mitochondrial acyl carrier protein 1, NADH-ubiquinone oxidoreductase acyl-carrier subunit, NADH-ubiquinone oxidoreductase acyl carrier protein, l(3)j4A6, mtACP" "IPR003231=Acyl carrier protein (ACP), IPR009081=Acyl carrier protein-like" CG9160 16-Dec-15 2015_12 "ENSDARG00000014915(ndufab1),ENSDARG00000058463(zgc:92607)" YKL192C(ACP1) WBGene00013237(Y56A3A.19) ENSXETG00000024430(ndufab1) ENSMUSG00000030869(Ndufab1) ENSG00000004779(NDUFAB1) " embryonic stage | stage >=14 , embryonic stage | stage >=15 , embryonic stage -- adult stage , adult stage && oogenesis stage | stage S10-11 " " embryonic/larval tracheal system

, embryonic/larval lateral trunk

, embryonic/larval dorsal trunk

, nurse cell

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,partially lethal - majority die,some die during pupal stage,viable" "spermatid,onion stage spermatid,germarium,trachea,trichogen cell,mesothoracic tergum" FBgn0263899 l(3)OL61 http://flybase.net/reports/FBgn0263899.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0000789 fs(1)C5 female sterile (1) C5 http://flybase.net/reports/FBgn0000789.html gene 16-Dec-15 2015_12 female sterile "chorion,ovary" FBgn0263470 snoRNA:Tudor-SN-a http://flybase.net/reports/FBgn0263470.html snoRNA_gene snoRNA:tudor-SN-a CR43585 16-Dec-15 2015_12 FBgn0053223 CG33223 http://flybase.net/reports/FBgn0053223.html protein_coding_gene "IPR000626=Ubiquitin domain, IPR029071=Ubiquitin-related domain, IPR015496=Ubiquilin" CG33223 16-Dec-15 2015_12 FBgn0038334 h-cup heineken-cup http://flybase.net/reports/FBgn0038334.html FBgn0044705 protein_coding_gene "CG6130, anon-WO0140519.172, h-cup, heineken-cup" IPR008555=Suppressor of IKBKE 1 CG6130 16-Dec-15 2015_12 viable FBgn0043383 EP596 EP596 http://flybase.net/reports/FBgn0043383.html gene EP0596 16-Dec-15 2015_12 visible "dorsocentral bristle,scutellar bristle,trichogen cell" FBgn0262948 CG43267 http://flybase.net/reports/FBgn0262948.html protein_coding_gene CG43267 16-Dec-15 2015_12 FBgn0051159 EF-G2 Elongation Factor G2 http://flybase.net/reports/FBgn0051159.html FBgn0038995 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003746=translation elongation factor activity" "0032790=ribosome disassembly, 0006414=translational elongation, 0032543=mitochondrial translation" 0005739=mitochondrion "CG6943, CG31159, dEF-G2" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR031157=Tr-type G domain, conserved site, IPR030851=Ribosome-releasing factor 2, mitochondrial, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain, IPR009022=Elongation factor G, III-V domain, IPR000640=Translation elongation factor EFG, V domain" CG31159 16-Dec-15 2015_12 ENSDARG00000005561(LOC100329815) YJL102W(MEF2) WBGene00022491(Y119D3B.14) ENSXETG00000005076(GFM2) ENSMUSG00000021666(Gfm2) ENSG00000164347(GFM2) FBgn0267619 CR45957 http://flybase.net/reports/FBgn0267619.html non_protein_coding_gene CR45957 16-Dec-15 2015_12 FBgn0002625 M(3)99B Minute (3) 99B http://flybase.net/reports/FBgn0002625.html gene "M(3)l, M(3)1, M" 16-Dec-15 2015_12 "Minute,dominant,visible,developmental rate defective" macrochaeta FBgn0046321 roX1-CES roX1 chromatin entry site http://flybase.net/reports/FBgn0046321.html region "roX1, roX1 DH site" 16-Dec-15 2015_12 FBgn0014323 l(3)ry151 lethal (3) ry151 http://flybase.net/reports/FBgn0014323.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050472 CG30472 http://flybase.net/reports/FBgn0050472.html protein_coding_gene CG30472 16-Dec-15 2015_12 viable FBgn0050047 CG30047 http://flybase.net/reports/FBgn0050047.html protein_coding_gene IPR007484=Peptidase M28 CG30047 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0027620 Acf ATP-dependent chromatin assembly factor large subunit http://flybase.net/reports/FBgn0027620.html FBgn0021749 protein_coding_gene "0003677=DNA binding, 0004402=histone acetyltransferase activity, 0070615=nucleosome-dependent ATPase activity, 0005515=protein binding, 0008270=zinc ion binding" "0016584=nucleosome positioning, 0007517=muscle organ development, 0031445=regulation of heterochromatin assembly, 0006333=chromatin assembly or disassembly, 0043462=regulation of ATPase activity, 0031497=chromatin assembly, 0042766=nucleosome mobilization, 0048813=dendrite morphogenesis, 0048666=neuron development, 0006355=regulation of transcription, DNA-templated, 0008544=epidermis development, 0006334=nucleosome assembly, 0007399=nervous system development, 0045892=negative regulation of transcription, DNA-templated" "0016589=NURF complex, 0005634=nucleus, 0008623=CHRAC, 0016590=ACF complex" "Chromatin Accessibility Complex, ACF/CHRAC, ATP-utilizing chromatin assembly and remodeling factor, ACF, Acf-1, dCHRAC, dACF, CHRAC, 175K protein, CG1966, p175, p170, p170/p185, ACF1, CHRAC-175, Acf1, CAF, acf1" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013136=WSTF/Acf1/Cbp146, IPR018501=DDT domain superfamily, IPR011011=Zinc finger, FYVE/PHD-type, IPR019787=Zinc finger, PHD-finger, IPR001487=Bromodomain, IPR018500=DDT domain, subgroup, IPR028935=WHIM3 domain, IPR028941=WHIM2 domain, IPR001965=Zinc finger, PHD-type" CG1966 16-Dec-15 2015_12 ENSDARG00000063233 WBGene00019217(H20J04.2) ENSMUSG00000035021(Baz1a) ENSG00000198604(BAZ1A) embryonic stage -- adult stage "viable,fertile,visible,mitotic cell cycle defective,cell death defective,lethal,partially lethal - majority die,recessive,developmental rate defective,suppressor of variegation,non-suppressor of variegation" "eye,ommatidium,antenna,ectopic,supernumerary,photoreceptor cell | third instar larval stage,eye disc | third instar larval stage,morphogenetic furrow,nucleus | third instar larval stage2314,embryonic/larval salivary gland | third instar larval stage,S phase,nucleus | blastoderm stage" FBgn0065761 l(2)SH0478 lethal (2) SH0478 http://flybase.net/reports/FBgn0065761.html gene l(2)SH2 0478 16-Dec-15 2015_12 "lethal,recessive" FBgn0062571 Mod(var)E1377 Mod(var)E1377 http://flybase.net/reports/FBgn0062571.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" E1377 16-Dec-15 2015_12 "partially lethal - majority die,recessive,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0026662 l(1)G0178 lethal (1) G0178 http://flybase.net/reports/FBgn0026662.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037590 Or85b Odorant receptor 85b http://flybase.net/reports/FBgn0037590.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "85b, DOR115, 85A.1, DmOR85b, CG11735" "IPR004117=Olfactory receptor, Drosophila" CG11735 16-Dec-15 2015_12 viable FBgn0061156 l(2)30Ba lethal (2) 30Ba http://flybase.net/reports/FBgn0061156.html gene K2 16-Dec-15 2015_12 "lethal,recessive" FBgn0063376 snoRNA:U76:54Eb snoRNA:U76:54Eb http://flybase.net/reports/FBgn0063376.html snoRNA_gene "U76snoRNA, CR32891" CR32891 16-Dec-15 2015_12 FBgn0035298 SCOT Succinyl-CoA:3-ketoacid CoA transferase http://flybase.net/reports/FBgn0035298.html "FBgn0027933, FBgn0064797" protein_coding_gene 0008260=3-oxoacid CoA-transferase activity 0046952=ketone body catabolic process 0005759=mitochondrial matrix "CT1116, citric acid synthetase, DmSCOT, 3-oxoacid-CoA-transferase, 3-oxoacid CoA-transferase, CG1140, BcDNA:RH54340, 3-oxoacid-CoA transferase, cDNA B" "IPR012792=3-oxoacid CoA-transferase, subunit A, IPR004164=Coenzyme A transferase active site, IPR014388=3-oxoacid CoA-transferase, IPR004165=Coenzyme A transferase family I, IPR012791=3-oxoacid CoA-transferase, subunit B, IPR004163=Coenzyme A transferase binding site" CG1140 16-Dec-15 2015_12 "ENSDARG00000013063(oxct1a),ENSDARG00000054319(oxct1b)" WBGene00007330(C05C10.3) ENSXETG00000005892() "ENSMUSG00000022186(Oxct1),ENSMUSG00000076438(Oxct2b),ENSMUSG00000076436(Oxct2a)" "ENSG00000083720(OXCT1),ENSG00000198754(OXCT2)" "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0032485 CG9426 http://flybase.net/reports/FBgn0032485.html protein_coding_gene 0003779=actin binding "0042994=cytoplasmic sequestering of transcription factor, 0051726=regulation of cell cycle" 0005737=cytoplasm Ipp "IPR006652=Kelch repeat type 1, IPR017096=BTB-kelch protein, IPR011705=BTB/Kelch-associated, IPR000210=BTB/POZ domain, IPR015916=Galactose oxidase, beta-propeller, IPR011333=POZ domain" CG9426 16-Dec-15 2015_12 ENSXETG00000003495(IPP) ENSMUSG00000028696(Ipp) ENSG00000197429(IPP) "viable,fertile" FBgn0025712 CG13920 http://flybase.net/reports/FBgn0025712.html FBgn0035250 protein_coding_gene "BEST:CK00246, CK00246" IPR029693=Transmembrane protein 35 CG13920 16-Dec-15 2015_12 ENSDARG00000052567(tmem35) ENSXETG00000007096() ENSMUSG00000033578(Tmem35) ENSG00000126950(TMEM35) "lethal,viable" FBgn0085645 CG41425 http://flybase.net/reports/FBgn0085645.html FBan0041425 protein_coding_gene 16-Dec-15 2015_12 FBgn0036874 brv1 brivido-1 http://flybase.net/reports/FBgn0036874.html protein_coding_gene "0005262=calcium channel activity, 0005509=calcium ion binding" "0070417=cellular response to cold, 0006816=calcium ion transport, 0050960=detection of temperature stimulus involved in thermoception" 0016020=membrane "CG9472, CT26822" "IPR003915=Polycystic kidney disease type 2 protein, IPR013122=Polycystin cation channel, PKD1/PKD2" CG9472 16-Dec-15 2015_12 "viable,cold stress response defective,recessive" FBgn0266701 CR45191 http://flybase.net/reports/FBgn0266701.html non_protein_coding_gene CR45191 16-Dec-15 2015_12 FBgn0262352 CG43050 http://flybase.net/reports/FBgn0262352.html protein_coding_gene "DMG8-chr2L.24.001, lincRNA.126" "IPR012674=Calycin, IPR011038=Calycin-like" CG43050 16-Dec-15 2015_12 FBgn0264722 CR43990 http://flybase.net/reports/FBgn0264722.html non_protein_coding_gene lincRNA.490 CR43990 16-Dec-15 2015_12 FBgn0260502 Pak::Pkn http://flybase.net/reports/FBgn0260502.html engineered_fusion_gene Pak-Pkn 16-Dec-15 2015_12 FBgn0036173 CG7394 http://flybase.net/reports/FBgn0036173.html FBgn0047099 protein_coding_gene 0001671=ATPase activator activity "0022008=neurogenesis, 0030150=protein import into mitochondrial matrix" "0001405=presequence translocase-associated import motor, 0005744=mitochondrial inner membrane presequence translocase complex" "BcDNA:RE52392, D.M.UKP, TIM14" IPR001623=DnaJ domain CG7394 16-Dec-15 2015_12 ENSDARG00000044420(dnajc19) YNL328C(MDJ2) WBGene00001039(dnj-21) ENSXETG00000010684(tim14) ENSMUSG00000022013(Dnajc15) ENSG00000205981(DNAJC19) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0086855 CG17078 http://flybase.net/reports/FBgn0086855.html "FBgn0031243, FBgn0017441" protein_coding_gene "unnamed, anon-21Cb" CG17078 16-Dec-15 2015_12 "ENSDARG00000068921,ENSDARG00000054974,ENSDARG00000068792,ENSDARG00000069779,ENSDARG00000071729,ENSDARG00000071728,ENSDARG00000068131,ENSDARG00000067616,ENSDARG00000002872(zgc:113210),ENSDARG00000069536,ENSDARG00000055263,ENSDARG00000068569,ENSDARG00000068945,ENSDARG00000057102,ENSDARG00000068773,ENSDARG00000057292,ENSDARG00000069579,ENSDARG00000068085,ENSDARG00000056264" "viable,body color defective" mesothoracic tergum FBgn0011131 l(1)Q205 lethal (1) Q205 http://flybase.net/reports/FBgn0011131.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0025137 su(RpII140Z36)S10 su(RpII140Z36)S10 http://flybase.net/reports/FBgn0025137.html gene Z36[S10] 16-Dec-15 2015_12 FBgn0250736 l(3)S002237 lethal (3) S002237 http://flybase.net/reports/FBgn0250736.html gene l(3)s002237 16-Dec-15 2015_12 lethal FBgn0060445 l(3)S122413a lethal (3) S122413a http://flybase.net/reports/FBgn0060445.html gene 1224/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0058456 18SrRNA:CR40456 18SrRNA:CR40456 http://flybase.net/reports/FBgn0058456.html rRNA_gene CR40456 16-Dec-15 2015_12 FBgn0266983 CR45434 http://flybase.net/reports/FBgn0266983.html non_protein_coding_gene CR45434 16-Dec-15 2015_12 FBgn0031310 Vps29 Vacuolar protein sorting 29 http://flybase.net/reports/FBgn0031310.html protein_coding_gene 0008565=protein transporter activity "0042147=retrograde transport, endosome to Golgi" "0031902=late endosome membrane, 0005768=endosome, 0030906=retromer complex, inner shell" "Vps29, DmVps29, CG4764, VPS29" "IPR028661=Vacuolar protein sorting-associated protein 29, Vps29, IPR024654=Calcineurin-like phosphoesterase domain, lpxH type, IPR029052=Metallo-dependent phosphatase-like, IPR000979=Phosphodiesterase MJ0936/Vps29" CG4764 16-Dec-15 2015_12 ENSDARG00000069521(vps29) YHR012W(VPS29) WBGene00014234(vps-29) ENSXETG00000024476(vps29) ENSMUSG00000029462(Vps29) ENSG00000111237(VPS29) "viable,fertile" FBgn0046335 en::Xlae\Meis3 Meis3 http://flybase.net/reports/FBgn0046335.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,heat sensitive,visible" "eye,ectopic,antenna,leg,distal,third segment of antenna,analia,genital disc" FBgn0065954 l(2)SH0065 lethal (2) SH0065 http://flybase.net/reports/FBgn0065954.html gene l(2)SH2 0065 16-Dec-15 2015_12 "lethal,recessive" FBgn0050031 CG30031 http://flybase.net/reports/FBgn0050031.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "endoproteinase I, endo-I" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG30031 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" FBgn0033627 CG13204 http://flybase.net/reports/FBgn0033627.html protein_coding_gene 0003677=DNA binding 13204 "IPR004210=BESS motif, IPR006578=MADF domain" CG13204 16-Dec-15 2015_12 ENSDARG00000068975 "viable,fertile" FBgn0023123 anon-10Ak anon-10Ak http://flybase.net/reports/FBgn0023123.html gene 3 16-Dec-15 2015_12 FBgn0266529 T:SS-BiP Signal sequence of Hsc70-3 http://flybase.net/reports/FBgn0266529.html engineered_tag 16-Dec-15 2015_12 FBgn0265082 Cdep Chondrocyte-derived ezrin-like domain containing protein ortholog (H. sapiens) http://flybase.net/reports/FBgn0265082.html "FBgn0051536, FBgn0037286, FBgn0037287, FBgn0062431, FBgn0063301, FBgn0085335" protein_coding_gene "0008092=cytoskeletal protein binding, 0003677=DNA binding, 0005089=Rho guanyl-nucleotide exchange factor activity, 0003779=actin binding" "0035023=regulation of Rho protein signal transduction, 0016601=Rac protein signal transduction" "0005856=cytoskeleton, 0005737=cytoplasm, 0019898=extrinsic component of membrane" "CG31536, CG34306, Cdep, CG2008, i23, CDEP, CG44193, BcDNA:RH50880, CG1283, BcDNA:AT26639" "IPR001849=Pleckstrin homology domain, IPR018979=FERM, N-terminal, IPR029071=Ubiquitin-related domain, IPR000299=FERM domain, IPR000219=Dbl homology (DH) domain, IPR014847=FERM adjacent (FA), IPR019749=Band 4.1 domain, IPR025898=Tc3 transposase, DNA binding domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR018980=FERM, C-terminal PH-like domain, IPR009057=Homeodomain-like, IPR019747=FERM conserved site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000798=Ezrin/radixin/moesin-like, IPR019748=FERM central domain" CG44193 16-Dec-15 2015_12 "ENSMUSG00000034066(Farp2),ENSMUSG00000025555(Farp1)" "ENSG00000006607(FARP2),ENSG00000152767(FARP1)" FBgn0263117 CG34377 http://flybase.net/reports/FBgn0263117.html "FBgn0040585, FBgn0085406, FBgn0038940, FBgn0038939, FBgn0040584" protein_coding_gene "CG13858, CG13861, CG13859, CG13860" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG34377 16-Dec-15 2015_12 FBgn0017623 Eig76Eb Eig76Eb http://flybase.net/reports/FBgn0017623.html gene "Eig76-2, Ecdysone-induced gene 76E" 16-Dec-15 2015_12 FBgn0025474 qkr58C quaking related 58C http://flybase.net/reports/FBgn0025474.html gene qrk58C 16-Dec-15 2015_12 FBgn0259971 CG42481 http://flybase.net/reports/FBgn0259971.html protein_coding_gene CG42481 16-Dec-15 2015_12 FBgn0028160 l(3)S041303 lethal (3) S041303 http://flybase.net/reports/FBgn0028160.html gene "l(3)041303, 0413/03" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0261633 CG42716 http://flybase.net/reports/FBgn0261633.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42716 16-Dec-15 2015_12 FBgn0027537 Nup93-1 Nucleoporin 93kD-1 http://flybase.net/reports/FBgn0027537.html protein_coding_gene "0005515=protein binding, 0017056=structural constituent of nuclear pore" "0006607=NLS-bearing protein import into nucleus, 0036228=protein targeting to nuclear inner membrane, 0007184=SMAD protein import into nucleus, 0006999=nuclear pore organization, 0034613=cellular protein localization" "0005643=nuclear pore, 0044615=nuclear pore nuclear basket" "Nup93, nup93, BcDNA:LD21129, CG11092" IPR007231=Nucleoporin interacting component Nup93/Nic96 CG11092 16-Dec-15 2015_12 ENSDARG00000003487(dye) YFR002W(NIC96) WBGene00003799(npp-13) ENSXETG00000018461(NUP93) ENSMUSG00000032939(Nup93) ENSG00000102900(NUP93) "visible,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266898 CR45358 http://flybase.net/reports/FBgn0266898.html non_protein_coding_gene CR45358 16-Dec-15 2015_12 FBgn0005273 l(3)SG93 lethal (3) SG93 http://flybase.net/reports/FBgn0005273.html gene l(3)V-13 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0016921 nompD no mechanoreceptor potential D http://flybase.net/reports/FBgn0016921.html gene nomp 16-Dec-15 2015_12 FBgn0005125 l(1)J413 lethal (1) J413 http://flybase.net/reports/FBgn0005125.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" testis FBgn0010724 l(3)00643 lethal (3) 00643 http://flybase.net/reports/FBgn0010724.html FBgn0011030 gene l(3)s2541 16-Dec-15 2015_12 "lethal,recessive" FBgn0002258 l(3)68Fc lethal (3) 68Fc http://flybase.net/reports/FBgn0002258.html gene "rose-gespleten region interval 20, l(3)rsg20, rsg20" 16-Dec-15 2015_12 "lethal,recessive" FBgn0039315 CG13658 http://flybase.net/reports/FBgn0039315.html protein_coding_gene "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG13658 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" FBgn0086694 Bre1 Bre1 http://flybase.net/reports/FBgn0086694.html "FBgn0035637, FBgn0010756" protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0016574=histone ubiquitination, 0016570=histone modification, 0007422=peripheral nervous system development, 0006909=phagocytosis" 0000790=nuclear chromatin "dBRE1, EC3-8, Bre-1, BRE1, CG10542, l(3)01640, bre1, bre-1, dBre1, lethal (3) 01640" "IPR018957=Zinc finger, C3HC4 RING-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG10542 16-Dec-15 2015_12 ENSDARG00000016664(LOC402838) YDL074C(BRE1) WBGene00007008(rfp-1) ENSXETG00000011951(RNF20) "ENSMUSG00000030816(Rnf40),ENSMUSG00000028309(Rnf20)" "ENSG00000103549(RNF40),ENSG00000155827(RNF20)" DRSC09742 IK -2.360815611 0.459077283 0.304333201 0.280659031 2.424965315 -0.290980604 FBgn0264831 CR44039 http://flybase.net/reports/FBgn0264831.html non_protein_coding_gene CR44039 16-Dec-15 2015_12 FBgn0263587 CR43612 http://flybase.net/reports/FBgn0263587.html non_protein_coding_gene CR43612 16-Dec-15 2015_12 FBgn0052428 CG32428 http://flybase.net/reports/FBgn0052428.html "FBgn0040631, FBgn0040632" protein_coding_gene "CG5145, CG13249" CG32428 16-Dec-15 2015_12 "viable,fertile,lethal" DRSC11697 IEK -1.964313201 -2.097166378 -1.186976646 -1.563281552 2.220659533 0.676294215 FBgn0067858 T:TM-sev Transmembrane and extracellular domain of sev http://flybase.net/reports/FBgn0067858.html engineered_tag T:sev 16-Dec-15 2015_12 FBgn0044055 HB\T T http://flybase.net/reports/FBgn0044055.html transposable_element_gene "0004803=transposase activity, 0003677=DNA binding" "0006313=transposition, DNA-mediated, 0015074=DNA integration" "IPR002492=Transposase, Tc1-like" 16-Dec-15 2015_12 FBgn0026608 Act42A::Act88F Act42A::Act88F http://flybase.net/reports/FBgn0026608.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0001835 l(1)ts612 lethal (1) ts612 http://flybase.net/reports/FBgn0001835.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0266000 CG44774 http://flybase.net/reports/FBgn0266000.html "FBgn0029738, FBgn0263836, FBgn0263837" protein_coding_gene "CR43698, CR43699, CG4068" IPR026065=FAM60A CG44774 16-Dec-15 2015_12 FBgn0262682 CR43152 http://flybase.net/reports/FBgn0262682.html non_protein_coding_gene CG43152 CR43152 16-Dec-15 2015_12 FBgn0003322 sbs stubs http://flybase.net/reports/FBgn0003322.html gene 16-Dec-15 2015_12 "viable,male fertile,female sterile,visible" "wing,wing vein L2,wing vein L3,eye" FBgn0003639 Su(wch) Suppressor of white-cherry http://flybase.net/reports/FBgn0003639.html gene "Suppressor of cherry, Su(w[ch2])" 16-Dec-15 2015_12 "lethal,recessive" FBgn0263345 CR43426 http://flybase.net/reports/FBgn0263345.html non_protein_coding_gene CR43426 16-Dec-15 2015_12 FBgn0032368 spag4 sperm-associated antigen 4 http://flybase.net/reports/FBgn0032368.html protein_coding_gene "0007286=spermatid development, 0030317=sperm motility, 0007283=spermatogenesis" "0005876=spindle microtubule, 0005879=axonemal microtubule, 0005634=nucleus, 0036064=ciliary basal body" "CG6589, dspag, giac, giacomo, Dspag4" IPR012919=SUN domain CG6589 16-Dec-15 2015_12 ENSDARG00000029638 "ENSMUSG00000040985(Sun3),ENSMUSG00000027480(Sun5)" "viable,male sterile,recessive,female fertile" "pre-elongation spermatid,elongation stage spermatid,spermatozoon,major mitochondrial derivative,minor mitochondrial derivative,individualization stage spermatid,cystic bulge,investment cone,waste bag" FBgn0040384 CG32795 http://flybase.net/reports/FBgn0040384.html "FBgn0029634, FBgn0040902, FBgn0052795" protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response" 0016021=integral component of membrane "CG2716, EG:BACN33B1.2, CG2766" IPR012926=TMPIT-like CG32795 16-Dec-15 2015_12 "ENSDARG00000030914(zgc:162139),ENSDARG00000042929(tmem120b),ENSDARG00000042379(zgc:103681)" WBGene00019716(M01G5.3) "ENSXETG00000003756(Q63ZG0_XENTR),ENSXETG00000008980(tmpit)" "ENSMUSG00000039886(Tmem120a),ENSMUSG00000054434(Tmem120b)" "ENSG00000188735(TMEM120B),ENSG00000189077" "viable,fertile,visible" pigment cell FBgn0000967 fs(2)eo7 female sterile (2) eo7 http://flybase.net/reports/FBgn0000967.html gene "0048477=oogenesis, 0008584=male gonad development, 0008585=female gonad development" "fs(2)eo-E, fs(2)eoPP22" 16-Dec-15 2015_12 "female sterile,male sterile" FBgn0070025 BG00459 BG00459 http://flybase.net/reports/FBgn0070025.html gene 16-Dec-15 2015_12 stress response defective FBgn0052450 CG32450 http://flybase.net/reports/FBgn0052450.html "FBgn0044650, FBgn0045809, FBgn0063221" protein_coding_gene "BcDNA:GH25462, BEST:GH25462, anon-WO0140519.221" CG32450 16-Dec-15 2015_12 viable FBgn0083237 EP2589 EP2589 http://flybase.net/reports/FBgn0083237.html gene 16-Dec-15 2015_12 FBgn0084937 3.1.38 3.1.38 http://flybase.net/reports/FBgn0084937.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0058390 CG40390 http://flybase.net/reports/FBgn0058390.html protein_coding_gene 16-Dec-15 2015_12 FBgn0066339 mus313 mus313 http://flybase.net/reports/FBgn0066339.html gene 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0014294 l(3)64Be lethal (3) 64Be http://flybase.net/reports/FBgn0014294.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0046887 Gr98b Gustatory receptor 98b http://flybase.net/reports/FBgn0046887.html "FBgn0039524, FBgn0041222, FBgn0045467, FBgn0051059" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "98B.2, CG31059, gustatory receptor 98b, GR98b, Gustatory receptor 98B.2, Gr98A1, GR98B.2, CG12884, Gr98B2" IPR013604=7TM chemoreceptor CG31059 16-Dec-15 2015_12 viable FBgn0263570 mir-4941 mir-4941 stem loop http://flybase.net/reports/FBgn0263570.html miRNA_gene "CR43555, dme-mir-4941" CR43555 16-Dec-15 2015_12 FBgn0050361 mtt mangetout http://flybase.net/reports/FBgn0050361.html "FBgn0020430, FBgn0033298, FBgn0033299, FBgn0046529, FBgn0046537" protein_coding_gene "0016595=glutamate binding, 0004930=G-protein coupled receptor activity, 0008066=glutamate receptor activity" "0008343=adult feeding behavior, 0017085=response to insecticide, 0007200=phospholipase C-activating G-protein coupled receptor signaling pathway" "0030425=dendrite, 0016021=integral component of membrane, 0005887=integral component of plasma membrane" "GluRB, DmGluRB, DmX receptor, Glu-RB, CG8692, anon-WO0170980.4, DmGluBR, CG18447, CG30361, anon-WO0170980.5, DmXR, mXr" "IPR000337=GPCR, family 3, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I, IPR000162=GPCR, family 3, metabotropic glutamate receptor, IPR017979=GPCR, family 3, conserved site, IPR011500=GPCR, family 3, nine cysteines domain, IPR017978=GPCR, family 3, C-terminal" CG30361 16-Dec-15 2015_12 "viable,feeding behavior defective,recessive" FBgn0058063 CG40063 http://flybase.net/reports/FBgn0058063.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263271 CG43397 http://flybase.net/reports/FBgn0263271.html protein_coding_gene CG43397 16-Dec-15 2015_12 FBgn0069974 CG40484 http://flybase.net/reports/FBgn0069974.html protein_coding_gene 16-Dec-15 2015_12 FBgn0038097 CG14384 http://flybase.net/reports/FBgn0038097.html protein_coding_gene CG14384 16-Dec-15 2015_12 viable FBgn0013350 dUTPase-i Deoxyuridine triphosphatase-inhibitor http://flybase.net/reports/FBgn0013350.html gene 0004858=dUTP pyrophosphatase inhibitor activity UTPase-i 16-Dec-15 2015_12 FBgn0065740 l(2)SH0527 lethal (2) SH0527 http://flybase.net/reports/FBgn0065740.html gene l(2)SH2 0527 16-Dec-15 2015_12 "lethal,recessive" FBgn0266111 ana3 anastral spindle 3 http://flybase.net/reports/FBgn0266111.html "FBgn0033718, FBgn0065728" protein_coding_gene "0044782=cilium organization, 0007052=mitotic spindle organization, 0051298=centrosome duplication, 0051297=centrosome organization, 0010457=centriole-centriole cohesion, 0032053=ciliary basal body organization, 0007099=centriole replication" "0036064=ciliary basal body, 0005814=centriole" "Ana3, lethal (2) SH0558, CG13162, l(2)SH0558, anastral spindle phenotype 3" "IPR029249=Rotatin, N-terminal, IPR030791=Rotatin" CG13162 16-Dec-15 2015_12 ENSG00000176225(RTTN) FBgn0033757 muskelin muskelin http://flybase.net/reports/FBgn0033757.html protein_coding_gene "0001556=oocyte maturation, 0001952=regulation of cell-matrix adhesion" 0005737=cytoplasm "unnamed, CG8811, Muskelin, DmMK" "IPR006652=Kelch repeat type 1, IPR010565=Muskelin, N-terminal, IPR015915=Kelch-type beta propeller, IPR008979=Galactose-binding domain-like, IPR006594=LIS1 homology motif, IPR006595=CTLH, C-terminal LisH motif" CG8811 16-Dec-15 2015_12 ENSDARG00000025576(mkln1) ENSXETG00000018173(MKLN1) ENSMUSG00000025609(Mkln1) ENSG00000128585(MKLN1) "viable,fertile" FBgn0053243 Ste:CG33243 Ste:CG33243 http://flybase.net/reports/FBgn0053243.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33243" "IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR000704=Casein kinase II, regulatory subunit" CG33243 16-Dec-15 2015_12 FBgn0065549 l(2)SH1042 lethal (2) SH1042 http://flybase.net/reports/FBgn0065549.html gene l(2)SH2 1042 16-Dec-15 2015_12 "lethal,recessive" FBgn0265319 tio::tsh http://flybase.net/reports/FBgn0265319.html engineered_fusion_gene Tsh/Tio 16-Dec-15 2015_12 "eye,ectopic,antennal disc,somatic clone,ventral" FBgn0065868 l(2)SH0261 lethal (2) SH0261 http://flybase.net/reports/FBgn0065868.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0084285 l(3)S026421 l(3)S026421 http://flybase.net/reports/FBgn0084285.html gene 16-Dec-15 2015_12 FBgn0024977 CG2709 http://flybase.net/reports/FBgn0024977.html protein_coding_gene 0008270=zinc ion binding EG:95B7.5 "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG2709 16-Dec-15 2015_12 WBGene00006976(zhp-3) "viable,fertile" FBgn0042132 CG18809 http://flybase.net/reports/FBgn0042132.html FBgn0064130 protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen, 0008340=determination of adult lifespan" 0005751=mitochondrial respiratory chain complex IV CG1809 CG18809 16-Dec-15 2015_12 ENSG00000123144(C19orf43) "long lived,female,RU486 conditional,viable" FBgn0259818 CG42399 http://flybase.net/reports/FBgn0259818.html "FBgn0031226, FBgn0031225, CG11620, CG4648" protein_coding_gene "CG4648, CG11620" "IPR024395=CLASP N-terminal domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG42399 16-Dec-15 2015_12 ENSMUSG00000035614(Fam179b) ENSG00000198718(FAM179B) DRSC00322 K 0.084648327 0.413390698 0.153032731 0.343758312 0.979525903 -1.520379021 FBgn0002606 M(2)58F Minute (2) 58F http://flybase.net/reports/FBgn0002606.html gene "M[[l']], Ml, M(2)l, M(2R)l" 16-Dec-15 2015_12 "developmental rate defective,dominant,visible,Minute,small body,lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,posterior dorsocentral bristle,posterior scutellar bristle,femur & macrochaeta,eye" FBgn0069129 mei(2)yoh7134 mei(2)yoh7134 http://flybase.net/reports/FBgn0069129.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0051339 CR31339 http://flybase.net/reports/FBgn0051339.html non_protein_coding_gene 16-Dec-15 2015_12 DRSC22960 K -0.966555257 1.077934321 -0.094877528 -0.100327325 0.092900065 2.179497644 FBgn0069155 mcl(3)Z2592 mcl(3)Z2592 http://flybase.net/reports/FBgn0069155.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0011888 tRNA:K2:42Ab transfer RNA:lys2:42Ab http://flybase.net/reports/FBgn0011888.html "FBgn0003795, FBgn0011886, FBgn0050311, FBgn0050516, FBgn0060187" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30311, tRNA:K:CTT:AE002769-b, 35SLys, tRNA Lys, CR30516, chr2R.trna95-LysCTT, tRNA:lys2:42Ab, tRNAlys, tRNA:K2, tRNA[Lys][[2]], AE002769.trna4-LysCTT" CR30516 16-Dec-15 2015_12 FBgn0265541 CR44391 http://flybase.net/reports/FBgn0265541.html pseudogene_attribute CR44391 16-Dec-15 2015_12 FBgn0085205 CG34176 http://flybase.net/reports/FBgn0085205.html protein_coding_gene CG34176 16-Dec-15 2015_12 FBgn0005553 l(3)85Ff lethal (3) 85Ff http://flybase.net/reports/FBgn0005553.html gene 16-Dec-15 2015_12 lethal FBgn0260622 2L2686 http://flybase.net/reports/FBgn0260622.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0084033 CG41473 http://flybase.net/reports/FBgn0084033.html FBan0041473 protein_coding_gene 16-Dec-15 2015_12 FBgn0040491 Buffy Buffy http://flybase.net/reports/FBgn0040491.html FBgn0033646 protein_coding_gene "0006915=apoptotic process, 0012501=programmed cell death, 0016239=positive regulation of macroautophagy, 0035234=ectopic germ cell programmed cell death, 0042981=regulation of apoptotic process, 0009267=cellular response to starvation, 0043068=positive regulation of programmed cell death, 0043066=negative regulation of apoptotic process" 0005783=endoplasmic reticulum "dbuffy, Bcl-2-48AE, Buffy/dBorg-2, Drob2, 48A-E Bcl-2-like, BUFFY, Buffy/DBorg-2, dBorg2, dBorg-2, dBORG-2/BUFFY, Buffy/Borg2, buffy, CG8238, Dbx" "IPR026298=Blc2 family, IPR026309=Bcl-2-related ovarian killer protein, IPR002475=Bcl2-like" CG8238 16-Dec-15 2015_12 "ENSDARG00000052129(boka),ENSDARG00000008807(bokb)" "ENSXETG00000025175(BCL2L1),ENSXETG00000014599(bcl2l2),ENSXETG00000024124(BCL2)" ENSMUSG00000026278(Bok) ENSG00000176720(BOK) pupal stage salivary gland

"viable,fertile,increased cell death,decreased cell death,conditional,mitotic cell cycle defective,lethal,partially,short lived" "presumptive embryonic/larval nervous system,glial cell" FBgn0060342 l(3)S143907 lethal (3) S143907 http://flybase.net/reports/FBgn0060342.html gene 1439/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0012002 tRNA:V3b:90BC transfer RNA:val3b:90BC http://flybase.net/reports/FBgn0012002.html "FBgn0011997, FBgn0051572, FBgn0060022" tRNA_gene "0033452=GUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3R.trna15-ValCAC, tRNA:V:CAC:AE002708-a, tRNA:val3b:90BC, Val, tRNA:V3b, CR31572, tRNA[Val][[3b]], valine tRNA, AE002708.trna9-ValCAC" CR31572 16-Dec-15 2015_12 FBgn0039273 CG9996 http://flybase.net/reports/FBgn0039273.html protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" dibeta3GnT5 "IPR002495=Glycosyl transferase, family 8, IPR029044=Nucleotide-diphospho-sugar transferases" CG9996 16-Dec-15 2015_12 "ENSDARG00000044191(gxylt2),ENSDARG00000022550(gxylt1)" "ENSXETG00000015929(GLT8D4),ENSXETG00000006794(GXYLT1)" "ENSMUSG00000030074(Gxylt2),ENSMUSG00000036197(Gxylt1)" "ENSG00000151233(GXYLT1),ENSG00000172986(GXYLT2)" "viable,fertile" FBgn0085635 CG41370 http://flybase.net/reports/FBgn0085635.html FBan0041370 protein_coding_gene 16-Dec-15 2015_12 FBgn0030061 CG1785 http://flybase.net/reports/FBgn0030061.html protein_coding_gene 0022008=neurogenesis IPR011687=Ribosome biogenesis protein Nop53/GLTSCR2 CG1785 16-Dec-15 2015_12 WBGene00012692(Y39B6A.33) ENSXETG00000002782(Q5M787_XENTR) ENSMUSG00000041560(Gltscr2) ENSG00000105373(GLTSCR2) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032074 Tsp29Fa Tetraspanin 29Fa http://flybase.net/reports/FBgn0032074.html protein_coding_gene 0016021=integral component of membrane "CG9494, Dm.Tsp29Fa" "IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain, IPR018503=Tetraspanin, conserved site" CG9494 16-Dec-15 2015_12 "ENSDARG00000038288(cd151),ENSDARG00000001781(si:dkey-21h14.7),ENSDARG00000068629(cd151l)" ENSMUSG00000025351(Cd63) ENSG00000135404(CD63) viable FBgn0003527 stil stand still http://flybase.net/reports/FBgn0003527.html protein_coding_gene "0030237=female sex determination, 0007275=multicellular organismal development, 0048477=oogenesis, 0046660=female sex differentiation" 0000790=nuclear chromatin "Stil, CG8592, STAND STILL, 152072_at, Y10276, Stand still" CG8592 16-Dec-15 2015_12 adult stage && oogenesis stage " nurse cell

, germarium

" " larval stage | third instar , adult stage | female && oogenesis stage , larval stage | first instar , adult stage | male , embryonic stage | stage >=11 , larval stage | second instar , adult stage && oogenesis stage | stage S1-13 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-10 " " spermatogonium

, germline cell

, spermatocyte

, male germline stem cell

, primary spermatocyte cyst

, nurse cell

, ovary

, testis | restricted

, oocyte

" "viable,fertile,wild-type,lethal,heat sensitive,sex-determination defective,recessive,female sterile" "ovary,germline cell,female,egg chamber,dorsal appendage,chorion,oocyte" FBgn0085243 CG34214 http://flybase.net/reports/FBgn0085243.html protein_coding_gene Dm_2R:92173 CG34214 16-Dec-15 2015_12 FBgn0084521 l(3)S046604 l(3)S046604 http://flybase.net/reports/FBgn0084521.html gene 16-Dec-15 2015_12 FBgn0028857 CG12448 http://flybase.net/reports/FBgn0028857.html protein_coding_gene 0032027=myosin light chain binding BG:DS07486.4 "IPR000048=IQ motif, EF-hand binding site" CG12448 16-Dec-15 2015_12 viable FBgn0266050 CG44815 http://flybase.net/reports/FBgn0266050.html protein_coding_gene CG44815 16-Dec-15 2015_12 FBgn0266207 CR44902 http://flybase.net/reports/FBgn0266207.html non_protein_coding_gene CR44902 16-Dec-15 2015_12 FBgn0013719 pbr postscutellar bristles http://flybase.net/reports/FBgn0013719.html gene psb 16-Dec-15 2015_12 "visible,recessive" FBgn0067867 Mod(Prat:bw)3-8 Mod(Prat:bw)3-8 http://flybase.net/reports/FBgn0067867.html gene Mod-3-8 16-Dec-15 2015_12 FBgn0065982 iab-5E.s iab-5E.s http://flybase.net/reports/FBgn0065982.html gene "IAB5, iab-5E s, 5E" 16-Dec-15 2015_12 FBgn0022122 l(2)k06608b lethal (2) k06608b http://flybase.net/reports/FBgn0022122.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261534 l(2)34Fc lethal (2) 34Fc http://flybase.net/reports/FBgn0261534.html "FBgn0001968, FBgn0028915, FBgn0026299, FBgn0062987" protein_coding_gene 0004252=serine-type endopeptidase activity 0005576=extracellular region "A2, CG7532, l34Fc, l(2)br8, lethal group A2, lethal 8 in the black-reduced region, anon-EST:ParkEST060, br8, DS01068.5, BcDNA:RE60882, BG:DS01068.5" IPR002861=Reeler domain CG7532 16-Dec-15 2015_12 ENSDARG00000067579 ENSXETG00000013191(sdfr2) FBgn0260859 Bet3 BET3 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0260859.html "FBgn0035992, FBgn0045027" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0006891=intra-Golgi vesicle-mediated transport, 0006888=ER to Golgi vesicle-mediated transport, 0022008=neurogenesis, 0033227=dsRNA transport, 0016192=vesicle-mediated transport" "0030008=TRAPP complex, 0005737=cytoplasm" "dBet3, Bet3p, CG3911, Bet3, BET3" "IPR016721=Bet3-like protein, IPR007194=Transport protein particle (TRAPP) component, IPR024096=NO signalling/Golgi transport ligand-binding domain" CG3911 16-Dec-15 2015_12 ENSDARG00000045364(trappc3) YKR068C(BET3) WBGene00014222(ZK1098.5) ENSXETG00000004378(trappc3) ENSMUSG00000028847(Trappc3) ENSG00000054116(TRAPPC3) FBgn0051164 Ir94a Ionotropic receptor 94a http://flybase.net/reports/FBgn0051164.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "CG31164, IR94a, DmelIR94a, ionotropic receptor 94a" CG31164 16-Dec-15 2015_12 viable FBgn0060566 l(3)S096512 lethal (3) S096512 http://flybase.net/reports/FBgn0060566.html gene 0965/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0039501 CG5987 http://flybase.net/reports/FBgn0039501.html protein_coding_gene 0004835=tubulin-tyrosine ligase activity 0006464=cellular protein modification process IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase CG5987 16-Dec-15 2015_12 ENSDARG00000054023(ttll6) ENSXETG00000027619(TTLL13) "ENSMUSG00000045467(Ttll13),ENSMUSG00000038756(Ttll6)" "ENSG00000170703(TTLL6),ENSG00000213471(TTLL13)" viable FBgn0037958 CG6962 http://flybase.net/reports/FBgn0037958.html protein_coding_gene 0050290=sphingomyelin phosphodiesterase D activity IPR024129=Sphingomyelin phosphodiesterase 4 CG6962 16-Dec-15 2015_12 ENSDARG00000020730(smpd4) ENSXETG00000004252(SMPD4) ENSMUSG00000005899(Smpd4) ENSG00000136699(SMPD4) "viable,fertile" DRSC16153 E 0.329211786 0.493030602 0.603497637 -1.911813895 -0.499866218 -0.389856999 FBgn0052449 tRNA:CR32449 transfer RNA:CR32449 http://flybase.net/reports/FBgn0052449.html FBgn0060266 tRNA_gene 0033414=UGC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002647.trna3-CysGCA, CR32449, tRNA:C:GCA:AE002647, chr3L.trna34-CysGCA" CR32449 16-Dec-15 2015_12 FBgn0261867 hby homebody http://flybase.net/reports/FBgn0261867.html gene 0035177=larval foraging behavior 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038925 Cchl Cytochrome c heme lyase http://flybase.net/reports/FBgn0038925.html protein_coding_gene 0004408=holocytochrome-c synthase activity 0018063=cytochrome c-heme linkage 0005743=mitochondrial inner membrane "cytochrome c heme lyase, cchl, CG6022, cchL, Cytochrome c haem lyase" IPR000511=Cytochrome c/c1 haem-lyase CG6022 16-Dec-15 2015_12 "ENSDARG00000028131(hccsa),ENSDARG00000003051(hccs)" YAL039C(CYC3) WBGene00011527(cchl-1) ENSXETG00000018924(hccs) ENSMUSG00000031352(Hccs) ENSG00000004961(HCCS) "visible,recessive,somatic clone,lethal,viable" "eye,somatic clone,eye disc,trichogen cell,mesothoracic tergum" FBgn0004897 fd96Ca forkhead domain 96Ca http://flybase.net/reports/FBgn0004897.html protein_coding_gene "0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0048806=genitalia development, 0048813=dendrite morphogenesis, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0009888=tissue development, 0007389=pattern specification process" "0005667=transcription factor complex, 0005634=nucleus" "Dmfd4, fd4, FD4, CG11921" "IPR018122=Fork head domain conserved site1, IPR001766=Fork head domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG11921 16-Dec-15 2015_12 "ENSDARG00000045569(foxb1.2),ENSDARG00000053650,ENSDARG00000069939,ENSDARG00000037475(LOC559714)" WBGene00003017(lin-31) "ENSXETG00000010836(BC088566.1),ENSXETG00000016337(FOXD2),ENSXETG00000016818(foxd1)" "ENSMUSG00000059246(Foxb1),ENSMUSG00000056829(Foxb2)" ENSG00000170608(FOXA3) embryonic stage " sensory neuron

, neuroblast

, head

, embryonic peripheral nervous system

" viable DRSC16946 E -0.211455591 -1.456618165 -0.273410425 -1.680186769 -0.015161358 -0.003099701 FBgn0069060 EP-M269 BEST:RE41386 http://flybase.net/reports/FBgn0069060.html gene "EST:RE41386, BEST:RE41386" 16-Dec-15 2015_12 "ventral nerve cord commissure,longitudinal connective" FBgn0046710 GIIIB GIIIB http://flybase.net/reports/FBgn0046710.html gene 0004623=phospholipase A2 activity 0005576=extracellular region dGIIIB 16-Dec-15 2015_12 FBgn0052703 Erk7 Extracellularly regulated kinase 7 http://flybase.net/reports/FBgn0052703.html "FBgn0030118, FBgn0030119" protein_coding_gene "0005524=ATP binding, 0004707=MAP kinase activity, 0004674=protein serine/threonine kinase activity" "0034198=cellular response to amino acid starvation, 0045792=negative regulation of cell size, 0007030=Golgi organization, 0050709=negative regulation of protein secretion, 0090278=negative regulation of peptide hormone secretion, 0034389=lipid particle organization, 0040015=negative regulation of multicellular organism growth, 0006468=protein phosphorylation, 0009267=cellular response to starvation" "0005635=nuclear envelope, 0005789=endoplasmic reticulum membrane, 0005737=cytoplasm" "CG2309, ERK7, CG32703, CG17441, Extracellularly regulated kinase 7" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site" CG32703 16-Dec-15 2015_12 ENSDARG00000023110(mapk7) ENSXETG00000013405(MAPK15) ENSMUSG00000063704(Mapk15) viable FBgn0054041 CG34041 http://flybase.net/reports/FBgn0054041.html "FBan0031018, FBgn0051018, FBgn0082873" protein_coding_gene "0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum "unnamed, BP1033, CG31018" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG34041 16-Dec-15 2015_12 FBgn0263290 CR43399 http://flybase.net/reports/FBgn0263290.html non_protein_coding_gene CR43399 16-Dec-15 2015_12 FBgn0038686 CG5555 http://flybase.net/reports/FBgn0038686.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0005737=cytoplasm "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011422=BRCA1-associated 2, IPR001607=Zinc finger, UBP-type, IPR001841=Zinc finger, RING-type" CG5555 16-Dec-15 2015_12 YHL010C(ETP1) WBGene00017144(EEED8.16) ENSXETG00000020916(BRAP) ENSMUSG00000029458(Brap) ENSG00000089234(BRAP) "visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,trichogen cell,mesothoracic tergum" FBgn0040115 l(2)23Db lethal (2) 23Db http://flybase.net/reports/FBgn0040115.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259917 CG42446 http://flybase.net/reports/FBgn0259917.html protein_coding_gene CG42446 16-Dec-15 2015_12 FBgn0266972 CR45423 http://flybase.net/reports/FBgn0266972.html "FBgn0265647, FBgn0265848" non_protein_coding_gene "CR44454, CR44637" CR45423 16-Dec-15 2015_12 FBgn0000345 com-d compressed dilapidator http://flybase.net/reports/FBgn0000345.html gene 16-Dec-15 2015_12 "visible,recessive" "leg,wing" FBgn0017432 anon-4Bb anon-4Bb http://flybase.net/reports/FBgn0017432.html gene Gene C 16-Dec-15 2015_12 FBgn0031049 Sec61ë_ Sec61 ë_ subunit http://flybase.net/reports/FBgn0031049.html protein_coding_gene "0008565=protein transporter activity, 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity" "0006616=SRP-dependent cotranslational protein targeting to membrane, translocation, 0010507=negative regulation of autophagy" 0005784=Sec61 translocon complex "Sec61, CG14214, Sec61gamma" "IPR022943=Preprotein translocase subunit SecE, IPR008158=Protein translocase SEC61 complex, gamma subunit, IPR001901=Protein translocase complex, SecE/Sec61-gamma subunit, IPR023391=Protein translocase SecE domain" CG14214 16-Dec-15 2015_12 ENSDARG00000018637(sec61g) YDR086C(SSS1) WBGene00001303(emo-1) ENSXETG00000015843(SEC61G) "ENSMUSG00000078974(Sec61g),ENSMUSG00000078109(Gm4184)" ENSG00000132432(SEC61G) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0267297 CR45733 http://flybase.net/reports/FBgn0267297.html non_protein_coding_gene CR45733 16-Dec-15 2015_12 FBgn0000473 Cyp6a2 Cytochrome P450-6a2 http://flybase.net/reports/FBgn0000473.html FBgn0010312 protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding, 0005506=iron ion binding" "0046680=response to DDT, 0055114=oxidation-reduction process, 0031000=response to caffeine" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "cyp6a2, cytochrome P450, CYP6a2, 6a2, P-450, P-450-B, CG9438, Cytochrome P450 6a2, Cytochrome P450 B1, 91-R, Cyp6a, cytochrome P450-B1, P450-B1, P450, 91R, Cyt-P450-B1, 143127_at, CYP6A2, P450-B, Cytochrome P450, Cyp6A2, unnamed" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG9438 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "chemical resistant,chemical sensitive,viable" FBgn0034049 bdg bedraggled http://flybase.net/reports/FBgn0034049.html protein_coding_gene "0005326=neurotransmitter transporter activity, 0005328=neurotransmitter:sodium symporter activity" "0007464=R3/R4 cell fate commitment, 0006836=neurotransmitter transport" 0016021=integral component of membrane CG8291 IPR000175=Sodium:neurotransmitter symporter CG8291 16-Dec-15 2015_12 "planar polarity defective,lethal,recessive,uncoordinated,locomotor behavior defective,flightless,viable" "ommatidium,eye photoreceptor cell,antennal disc,eye disc,somatic clone" DRSC07136 I -0.588875522 -2.53956738 -0.574093469 0.242152711 0.914409732 -0.067525446 FBgn0030903 CG15060 http://flybase.net/reports/FBgn0030903.html protein_coding_gene 16-Dec-15 2015_12 DRSC19634 IEK -0.468898151 -4.736403253 -0.944840268 -5.53699024 -4.030046297 -5.193921646 FBgn0001503 l(1)10Da lethal (1) 10Da http://flybase.net/reports/FBgn0001503.html FBgn0001862 gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect,partially lethal - majority die" "egg,germline clone" FBgn0003450 snk snake http://flybase.net/reports/FBgn0003450.html FBgn0015383 protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity, 0008233=peptidase activity" "0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway, 0006508=proteolysis, 0016485=protein processing" 0005576=extracellular region "SNK, Snake, l(3)87Dg, SP26, CG7996, Snk, me(3)4, c-SP26" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG7996 16-Dec-15 2015_12 "ENSXETG00000016792(plat),ENSXETG00000007245(F12),ENSXETG00000005495(HGFAC),ENSXETG00000018616(HABP2),ENSXETG00000010002(),ENSXETG00000004035(PRSS12)" "ENSMUSG00000025075(Habp2),ENSMUSG00000029102(Hgfac),ENSMUSG00000031538(Plat),ENSMUSG00000021822(Plau),ENSMUSG00000021492(F12),ENSMUSG00000027978(Prss12)" embryonic stage | 0-4 hr "wild-type,female sterile,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,lethal,maternal effect,viable" "embryonic/first instar larval cuticle,maternal effect,ventral,denticle belt,filzkorper" FBgn0052725 CG32725 http://flybase.net/reports/FBgn0052725.html protein_coding_gene 16-Dec-15 2015_12 FBgn0043049 anon-60Ad anon-60Ad http://flybase.net/reports/FBgn0043049.html gene 16-Dec-15 2015_12 FBgn0020524 ms(3)CB27 ms(3)CB27 http://flybase.net/reports/FBgn0020524.html gene 16-Dec-15 2015_12 "male sterile,recessive" FBgn0026236 kugi kugi http://flybase.net/reports/FBgn0026236.html gene 0007338=single fertilization "homer, homr" 16-Dec-15 2015_12 FBgn0001072 Fs(3)Zol Female sterile (3) Zolta http://flybase.net/reports/FBgn0001072.html gene "Fs(3)Zolta, Fs(3)Sz32" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0026634 ldlCp ldlCp-related protein http://flybase.net/reports/FBgn0026634.html protein_coding_gene "0006891=intra-Golgi vesicle-mediated transport, 0007030=Golgi organization, 0033227=dsRNA transport, 0006887=exocytosis, 0015031=protein transport" "0005802=trans-Golgi network, 0016020=membrane" "CG6177, ldl-Cp" "IPR024602=Conserved oligomeric Golgi complex, subunit 2, N-terminal, IPR024603=COG complex component, COG2, C-terminal, IPR009316=COG complex component, COG2" CG6177 16-Dec-15 2015_12 ENSDARG00000004037(cog2) WBGene00000585(cogc-2) ENSXETG00000023340(COG2) ENSMUSG00000031979(Cog2) ENSG00000135775(COG2) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0084179 fz::wg fz::wg http://flybase.net/reports/FBgn0084179.html engineered_fusion_gene 16-Dec-15 2015_12 embryonic/first instar larval cuticle FBgn0015528 pff parallel fused fascicles http://flybase.net/reports/FBgn0015528.html gene 16-Dec-15 2015_12 FBgn0085617 CG41327 http://flybase.net/reports/FBgn0085617.html FBan0041327 protein_coding_gene 16-Dec-15 2015_12 FBgn0266640 CR45147 http://flybase.net/reports/FBgn0266640.html non_protein_coding_gene CR45147 16-Dec-15 2015_12 FBgn0083023 snoRNA:ë¬18S-640d snoRNA:ë¬18S-640d http://flybase.net/reports/FBgn0083023.html snoRNA_gene "psi18s-640d, chr2L:20407188..20407294, CR34578" CR34578 16-Dec-15 2015_12 FBgn0065545 l(2)SH1052 lethal (2) SH1052 http://flybase.net/reports/FBgn0065545.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085765 2SrRNA-ë¬:CR40677 2S ribosomal RNA pseudogene:CR40677 http://flybase.net/reports/FBgn0085765.html FBan0040677 pseudogene_attribute CR40677 CR40677 16-Dec-15 2015_12 FBgn0084552 E-2c Enhancer on chromosome 2-complementation group c http://flybase.net/reports/FBgn0084552.html gene 16-Dec-15 2015_12 FBgn0263663 CR43654 http://flybase.net/reports/FBgn0263663.html non_protein_coding_gene CR43654 16-Dec-15 2015_12 FBgn0038840 CG5621 http://flybase.net/reports/FBgn0038840.html FBgn0044796 protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity" "0060025=regulation of synaptic activity, 0006811=ion transport" 0005886=plasma membrane "anon-WO0138359.5, DmelCG5621, DKaiRIC, CT17756" "IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320=Ionotropic glutamate receptor, IPR001508=Ionotropic glutamate receptor, metazoa, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I" CG5621 16-Dec-15 2015_12 ENSXETG00000017031(GRIK4) viable FBgn0267023 CR45467 http://flybase.net/reports/FBgn0267023.html non_protein_coding_gene CR45467 16-Dec-15 2015_12 FBgn0011124 l(1)Q86 lethal (1) Q86 http://flybase.net/reports/FBgn0011124.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0028371 jbug jitterbug http://flybase.net/reports/FBgn0028371.html "FBgn0034772, FBgn0034773, FBgn0040659, FBgn0041831, FBgn0050092" protein_coding_gene 0003779=actin binding "0009612=response to mechanical stimulus, 0048104=establishment of body hair or bristle planar orientation" "CG13525, Jbug, filamin, CG30092, CG11605, Filamin, AAF46896, CG3550" "IPR013783=Immunoglobulin-like fold, IPR001589=Actinin-type actin-binding domain, conserved site, IPR001298=Filamin/ABP280 repeat, IPR014756=Immunoglobulin E-set, IPR017868=Filamin/ABP280 repeat-like, IPR001715=Calponin homology domain" CG30092 16-Dec-15 2015_12 WBGene00016006(fln-2) "viable,fertile,bang sensitive,planar polarity defective" DRSC04167 K 0.271759414 -0.751950848 -0.585324758 -0.073074472 1.129731535 1.506923133 FBgn0267762 CR46093 http://flybase.net/reports/FBgn0267762.html non_protein_coding_gene CR46093 16-Dec-15 2015_12 FBgn0015393 hoip hoi-polloi http://flybase.net/reports/FBgn0015393.html FBgn0032137 protein_coding_gene 0003729=mRNA binding "0000398=mRNA splicing, via spliceosome, 0007399=nervous system development, 0007422=peripheral nervous system development, 0010608=posttranscriptional regulation of gene expression, 0042254=ribosome biogenesis, 0060415=muscle tissue morphogenesis" "0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus, 0005681=spliceosomal complex, 0005730=nucleolus, 0071011=precatalytic spliceosome" "CG3949, HOIP, Hoip, Hoi Polloi" "IPR018492=Ribosomal protein L7Ae/L8/Nhp2 family, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR004037=Ribosomal protein L7Ae conserved site, IPR029064=50S ribosomal protein L30e-like, IPR002415=H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote" CG3949 16-Dec-15 2015_12 "ENSDARG00000023299(nhp2l1),ENSDARG00000069878(zgc:56066)" YEL026W(SNU13) WBGene00010896(M28.5) ENSXETG00000026024(nhp2l1) "ENSMUSG00000063480(Nhp2l1),ENSMUSG00000063543(Gm5616)" ENSG00000100138(NHP2L1) "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "presumptive embryonic/larval peripheral nervous system,fascicle,embryonic somatic muscle,imaginal disc" DRSC03546 IEK -1.638928189 -0.985587344 -0.394625926 -7.665973904 -2.706352239 -0.931208665 FBgn0001103 gg goggle http://flybase.net/reports/FBgn0001103.html gene 0048477=oogenesis "l(1)7Fe, fs(1)C210, fs(1)N83" 16-Dec-15 2015_12 "visible,female sterile,male fertile,lethal,recessive,female fertile" "eye,ommatidium,adult head,wing,macrochaeta,trichome,trichome & adult abdomen,head bristle,oocyte" FBgn0263320 CG43401 http://flybase.net/reports/FBgn0263320.html protein_coding_gene CG43401 16-Dec-15 2015_12 FBgn0003186 qs quicksilver http://flybase.net/reports/FBgn0003186.html gene "l(1)10Fl, su(b)[18], faintoid, ftd, su(b)" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal,male,viable,cold sensitive,partially lethal - majority live,female" "cuticle,mouthpart,denticle belt,cephalopharyngeal skeleton,adult cuticle,male,macrochaeta,puparium" FBgn0263707 CG43659 http://flybase.net/reports/FBgn0263707.html protein_coding_gene Dm_2R:85606 CG43659 16-Dec-15 2015_12 FBgn0065657 l(2)SH0719 lethal (2) SH0719 http://flybase.net/reports/FBgn0065657.html gene l(2)SH2 0719 16-Dec-15 2015_12 "lethal,recessive" FBgn0085471 CG34442 http://flybase.net/reports/FBgn0085471.html "FBan0030070, FBgn0033930, FBgn0050070" protein_coding_gene CG30070 IPR006631=Protein of unknown function DM4/12 CG34442 16-Dec-15 2015_12 FBgn0003959 upw upward http://flybase.net/reports/FBgn0003959.html gene 16-Dec-15 2015_12 "wing,wing vein" FBgn0040524 CG11052 http://flybase.net/reports/FBgn0040524.html protein_coding_gene 0003998=acylphosphatase activity "IPR017968=Acylphosphatase, conserved site, IPR001792=Acylphosphatase-like domain, IPR020456=Acylphosphatase" CG11052 16-Dec-15 2015_12 viable FBgn0260486 Ziz Zizimin ortholog (H. sapiens) http://flybase.net/reports/FBgn0260486.html "FBgn0031919, FBgn0062907, FBgn0031921" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity 0035023=regulation of Rho protein signal transduction "CG42533, BcDNA:RH71439, Dm zizimin, CG6630, Dm ziz, CG15819" "IPR027007=DHR-1 domain, IPR027357=DHR-2 domain, IPR001849=Pleckstrin homology domain, IPR010703=Dedicator of cytokinesis C-terminal, IPR026791=Dedicator of cytokinesis, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG42533 16-Dec-15 2015_12 "ENSDARG00000016311(LOC562683),ENSDARG00000062485" WBGene00009065(F22G12.5) ENSXETG00000005142(DOCK10) "ENSMUSG00000025558(Dock9),ENSMUSG00000031093(Dock11),ENSMUSG00000038608(Dock10)" "ENSG00000088387(DOCK9),ENSG00000147251(DOCK11),ENSG00000135905(DOCK10)" FBgn0029662 CG12206 http://flybase.net/reports/FBgn0029662.html protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0009055=electron carrier activity" 0045454=cell redox homeostasis "IPR002109=Glutaredoxin, IPR012336=Thioredoxin-like fold" CG12206 16-Dec-15 2015_12 ENSDARG00000053692 ENSMUSG00000068082(Grxcr1) "ENSG00000204928(GRXCR2),ENSG00000215203(GRXCR1)" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267399 CR45761 http://flybase.net/reports/FBgn0267399.html non_protein_coding_gene CR45761 16-Dec-15 2015_12 FBgn0000716 fnc fine chaetae http://flybase.net/reports/FBgn0000716.html gene 16-Dec-15 2015_12 "visible,viable,male sterile,male,eye color defective" "macrochaeta,adult abdomen,wing,pigment cell,adult head" FBgn0011328 l(3)j2B9 lethal (3) j2B9 http://flybase.net/reports/FBgn0011328.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261706 CR42742 http://flybase.net/reports/FBgn0261706.html non_protein_coding_gene CR42742 16-Dec-15 2015_12 FBgn0020014 Egfr::Rat\Neu Neu http://flybase.net/reports/FBgn0020014.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0069925 CG41126 http://flybase.net/reports/FBgn0069925.html FBan0041126 protein_coding_gene 16-Dec-15 2015_12 FBgn0259357 C677 http://flybase.net/reports/FBgn0259357.html gene 16-Dec-15 2015_12 visible wing FBgn0087005 rtp retinophilin http://flybase.net/reports/FBgn0087005.html "FBgn0037302, FBgn0020322, FBgn0086684" protein_coding_gene 0043652=engulfment of apoptotic cell 0016028=rhabdomere "anon-83ABa, unnamed, Retinophilin, retin, uta, retinophilin, CG10233, undertaker, rtp, 9C4" IPR003409=MORN motif CG10233 16-Dec-15 2015_12 ENSDARG00000039062(morn4) ENSMUSG00000049670(Morn4) ENSG00000171160(MORN4) "neurophysiology defective,recessive,viable,body color defective" "rhabdomere,mesothoracic tergum" FBgn0082925 snoRNA:Or-aca1 snoRNA:Or-aca1 http://flybase.net/reports/FBgn0082925.html snoRNA_gene "CR34561, DmOr_aca1 snoRNA, Or-aca1, DmOr_aca1" CR34561 16-Dec-15 2015_12 FBgn0069987 BG02100 BG02100 http://flybase.net/reports/FBgn0069987.html gene 16-Dec-15 2015_12 stress response defective FBgn0043489 fs(3)66EFa fs(3)66EFa http://flybase.net/reports/FBgn0043489.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0001151 gt-3 giant on 3 http://flybase.net/reports/FBgn0001151.html gene "giant in chromosome 3, gt3" 16-Dec-15 2015_12 male sterile FBgn0060412 l(3)S130008b lethal (3) S130008b http://flybase.net/reports/FBgn0060412.html gene 1300/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0019874 anon-92Ee anon-92Ee http://flybase.net/reports/FBgn0019874.html gene unnamed 16-Dec-15 2015_12 FBgn0010171 sey scratched eyes http://flybase.net/reports/FBgn0010171.html gene 16-Dec-15 2015_12 "eye,heat sensitive" FBgn0040001 FASN3 Fatty acid synthase 3 http://flybase.net/reports/FBgn0040001.html FBan0017374 protein_coding_gene "0016788=hydrolase activity, acting on ester bonds, 0008270=zinc ion binding, 0016491=oxidoreductase activity, 0004312=fatty acid synthase activity" "0006633=fatty acid biosynthetic process, 0055114=oxidation-reduction process" 0005835=fatty acid synthase complex "FAS[CG17374], FAS, DM_7289423, CG17374, FASN[CG17374]" "IPR014043=Acyl transferase, IPR029058=Alpha/Beta hydrolase fold, IPR016040=NAD(P)-binding domain, IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase, IPR013149=Alcohol dehydrogenase, C-terminal, IPR009081=Acyl carrier protein-like, IPR001031=Thioesterase, IPR013968=Polyketide synthase, ketoreductase domain, IPR011032=GroES-like, IPR016039=Thiolase-like, IPR014030=Beta-ketoacyl synthase, N-terminal, IPR001227=Acyl transferase domain, IPR016036=Malonyl-CoA ACP transacylase, ACP-binding, IPR014031=Beta-ketoacyl synthase, C-terminal, IPR020843=Polyketide synthase, enoylreductase domain, IPR018201=Beta-ketoacyl synthase, active site, IPR020807=Polyketide synthase, dehydratase domain" CG17374 16-Dec-15 2015_12 "ENSDARG00000068882,ENSDARG00000068878(si:dkey-61p9.11),ENSDARG00000071470" lethal - all die during larval stage embryonic/larval spiracle | larval stage FBgn0035505 Teh2 tipE homolog 2 http://flybase.net/reports/FBgn0035505.html protein_coding_gene 0017080=sodium channel regulator activity 0002028=regulation of sodium ion transport 0016021=integral component of membrane "CG15004, TEH2" CG15004 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0036856 CG9666 http://flybase.net/reports/FBgn0036856.html protein_coding_gene "0009007=site-specific DNA-methyltransferase (adenine-specific) activity, 0003676=nucleic acid binding" 0032259=methylation Dromel_CG9666_FBtr0074991_mORF "IPR007848=Methyltransferase small domain, IPR002052=DNA methylase, N-6 adenine-specific, conserved site, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG9666 16-Dec-15 2015_12 ENSDARG00000068893(mettl5) WBGene00008008(C38D4.9) ENSXETG00000018894(Q569E1_XENTR) ENSMUSG00000051730(Mettl5) ENSG00000138382(METTL5) "lethal,viable,fertile,wild-type" FBgn0040294 POSH Plenty of SH3s http://flybase.net/reports/FBgn0040294.html "FBgn0021835, FBgn0026595, FBgn0034244" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0019901=protein kinase binding, 0061630=ubiquitin protein ligase activity, 0008270=zinc ion binding, 0030159=receptor signaling complex scaffold activity" "0008104=protein localization, 0045087=innate immune response, 0008340=determination of adult lifespan, 0007390=germ-band shortening, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0008103=oocyte microtubule cytoskeleton polarization, 0060548=negative regulation of cell death, 0042052=rhabdomere development, 0008258=head involution, 0007391=dorsal closure, 0045451=pole plasm oskar mRNA localization, 0022407=regulation of cell-cell adhesion, 0032494=response to peptidoglycan" 0005829=cytosol "plenty of SH3s, Plenty of SH3 Domains, Plenty of SH3 domains, DPOSH, dPOSH, Plenty-of-SH3s, 155116_at, GM09451, CG4909, BEST:GM09451, posh, l(2)k15815" "IPR001452=SH3 domain, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR018957=Zinc finger, C3HC4 RING-type" CG4909 16-Dec-15 2015_12 "ENSDARG00000070462(LOC100329529),ENSDARG00000070470(si:dkey-15j16.4)" WBGene00021549(Y44E3A.4) "ENSXETG00000004943(sh3md2),ENSXETG00000018646(SH3RF3)" "ENSMUSG00000031642(Sh3rf1),ENSMUSG00000037990(Sh3rf3)" ENSG00000154447(SH3RF1) " embryonic stage | early , wandering third instar larval stage " dorsal mesothoracic disc && ventral thoracic disc

"majority die during embryonic stage,some die during embryonic stage,viable,fertile,melanotic mass phenotype,immune response defective,lethal,recessive,lethal - all die before end of embryonic stage,long lived,planar polarity defective,visible,wild-type,lethal - all die before end of second instar larval stage" "embryonic dorsal epidermis,embryonic head epidermis,germ band,melanotic mass,filamentous actin,embryonic leading edge cell,adherens junction,wing hair,genitalia,tarsal segment,macrochaeta,wing,eye,embryonic dorsal epidermis | dorsal closure stage,adult external thorax" FBgn0000066 Aldox-2 Aldehyde oxidase 2 http://flybase.net/reports/FBgn0000066.html gene aldox2 16-Dec-15 2015_12 FBgn0020352 anon-34Fa anon-34Fa http://flybase.net/reports/FBgn0020352.html gene 527 16-Dec-15 2015_12 FBgn0065809 l(2)SH0388 lethal (2) SH0388 http://flybase.net/reports/FBgn0065809.html gene l(2)SH2 0388 16-Dec-15 2015_12 "lethal,recessive" FBgn0039742 CG15528 http://flybase.net/reports/FBgn0039742.html protein_coding_gene "0017017=MAP kinase tyrosine/serine/threonine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0000188=inactivation of MAPK activity, 0006470=protein dephosphorylation" MKP-like "IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR024950=Dual specificity phosphatase, IPR000340=Dual specificity phosphatase, catalytic domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR020422=Dual specificity protein phosphatase domain" CG15528 16-Dec-15 2015_12 "ENSDARG00000057625(zgc:101746),ENSDARG00000067564(zgc:153044),ENSDARG00000059697" "YIL113W(SDP1),YNL053W(MSG5)" WBGene00007302(C04F12.8) "ENSXETG00000011338(DUSP14),ENSXETG00000019946()" "ENSMUSG00000018648(Dusp14),ENSMUSG00000047205(Dusp18),ENSMUSG00000025043(Dusp21)" "ENSG00000161326(DUSP14),ENSG00000167065(DUSP18),ENSG00000189037(DUSP21)" viable FBgn0004423 gustD gustatory-defective D http://flybase.net/reports/FBgn0004423.html "FBgn0001156, FBgn0001161" gene "gust[x6], gust[x3]" 16-Dec-15 2015_12 "taste perception defective,heat sensitive,dominant,partially" FBgn0265852 CR44641 http://flybase.net/reports/FBgn0265852.html non_protein_coding_gene CR44641 16-Dec-15 2015_12 FBgn0002876 mul multiple http://flybase.net/reports/FBgn0002876.html FBgn0001681 gene "l(1)ESHS2, l(1)1Cb" 16-Dec-15 2015_12 "visible,female sterile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,polyphasic,cell lethal,germline clone" "eye,wing,macrochaeta" FBgn0052128 tRNA:CR32128 transfer RNA:CR32128 http://flybase.net/reports/FBgn0052128.html FBgn0060125 tRNA_gene 0033421=CCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:P:AGG:AE002602-b, AE002602.trna17-ProAGG, CR32128, chr3L.trna23-ProAGG" CR32128 16-Dec-15 2015_12 FBgn0263216 CG43386 http://flybase.net/reports/FBgn0263216.html "FBgn0030166, FBgn0047067, FBgn0030165" protein_coding_gene "CG15250, BcDNA:RE65233, CG15251" CG43386 16-Dec-15 2015_12 FBgn0024236 foi fear-of-intimacy http://flybase.net/reports/FBgn0024236.html "FBgn0013623, FBgn0024528, FBgn0026232, FBgn0035908" protein_coding_gene 0005385=zinc ion transmembrane transporter activity "0055085=transmembrane transport, 0022008=neurogenesis, 0007506=gonadal mesoderm development, 0035147=branch fusion, open tracheal system, 0008406=gonad development, 0006829=zinc II ion transport, 0035262=gonad morphogenesis, 0007417=central nervous system development, 0007280=pole cell migration, 0016477=cell migration, 0008354=germ cell migration" "0016323=basolateral plasma membrane, 0005886=plasma membrane, 0009986=cell surface" "cg6817, l(3)j8E8, kas, CG6817, kastchen, fear of intimacy, l(3)neo13, FOI, dFOI" IPR003689=Zinc/iron permease CG6817 16-Dec-15 2015_12 "ENSDARG00000005823(slc39a10),ENSDARG00000068143(LOC100333432)" YIL023C(YKE4) WBGene00021936(Y55F3BL.2) "ENSXETG00000022134(SLC39A10),ENSXETG00000014976(SLC39A6)" "ENSMUSG00000025986(Slc39a10),ENSMUSG00000024270(Slc39a6)" "ENSG00000196950(SLC39A10),ENSG00000141424(SLC39A6)" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,rescuable maternal effect,viable,visible,lethal - all die during larval stage" "commissure,eye disc,presumptive embryonic/larval central nervous system,midline glial cell,gonadal sheath proper primordium,fat body/gonad primordium,gonad,precursor,longitudinal connective,eye,anterior,ocellus,head bristle,interface glial cell,peripheral glial cell,somatic clone,glial cell & eye disc | cell non-autonomous | somatic clone,presumptive embryonic/larval muscle system,lateral transverse muscle,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,embryonic/first instar larval cuticle,germline clone,lateral trunk primordium,presumptive embryonic/larval tracheal system,germline cell,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC10719 IEK -2.094493419 -2.866492547 -1.258620713 -5.373954452 0.821453966 1.939419669 FBgn0000511 du dunkel http://flybase.net/reports/FBgn0000511.html gene 16-Dec-15 2015_12 "male fertile,female sterile,dominant,lethal,recessive,cold sensitive,visible,body color defective" wing FBgn0032430 CG6388 http://flybase.net/reports/FBgn0032430.html protein_coding_gene "0003723=RNA binding, 0004809=tRNA (guanine-N2-)-methyltransferase activity" 0006400=tRNA modification "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR002905=tRNA methyltransferase, Trm1" CG6388 16-Dec-15 2015_12 ENSDARG00000010978 YDR120C(TRM1) WBGene00006613(trm-1) ENSMUSG00000001909(Trmt1) ENSG00000104907(TRMT1) FBgn0038964 Nop56 Nop56 http://flybase.net/reports/FBgn0038964.html protein_coding_gene "0009267=cellular response to starvation, 0022008=neurogenesis" "0005730=nucleolus, 0030532=small nuclear ribonucleoprotein complex" "FBgn0038964, Dnop56, CG13849, DmNop56, nop56" "IPR012974=NOP5, N-terminal, IPR012976=NOSIC, IPR002687=Nop domain" CG13849 16-Dec-15 2015_12 ENSDARG00000012820(nop56) YLR197W(NOP56) WBGene00010627(K07C5.4) ENSXETG00000014962() ENSMUSG00000027405(Nop56) ENSG00000101361(NOP56) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0005745 l(1)TK237 lethal (1) TK237 http://flybase.net/reports/FBgn0005745.html gene l237 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0264417 FCO-B http://flybase.net/reports/FBgn0264417.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0085480 CG34451 http://flybase.net/reports/FBgn0085480.html "FBgn0082857, FBgn0053999" protein_coding_gene 0008378=galactosyltransferase activity 0006486=protein glycosylation CG33999 CG34451 16-Dec-15 2015_12 FBgn0266382 CR45024 http://flybase.net/reports/FBgn0266382.html non_protein_coding_gene CR45024 16-Dec-15 2015_12 FBgn0086388 BG01693 http://flybase.net/reports/FBgn0086388.html gene "0042048=olfactory behavior, 0002121=inter-male aggressive behavior" 16-Dec-15 2015_12 "viable,smell perception defective,behavior defective,recessive" FBgn0040046 CG12578 http://flybase.net/reports/FBgn0040046.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265947 CR44734 http://flybase.net/reports/FBgn0265947.html non_protein_coding_gene CR44734 16-Dec-15 2015_12 FBgn0011741 Arp6 Actin-related protein 6 http://flybase.net/reports/FBgn0011741.html protein_coding_gene 0003682=chromatin binding "0070828=heterochromatin organization, 0006338=chromatin remodeling" "0005634=nucleus, 0000785=chromatin" "CG11678, actr13E, Actin-related protein 13E, actin-related protein, ARP13E, Actr13E, ARP, Acrp, Arp13E, ARP(13E), arp4, dArp6, unnamed, Arp4" "IPR004000=Actin family, IPR030054=Actin-related protein 6" CG11678 16-Dec-15 2015_12 ENSDARG00000021370(actr6) WBGene00007434(C08B11.6) ENSXETG00000001885(TEgg077g12.1) ENSMUSG00000019948(Actr6) ENSG00000075089(ACTR6) embryonic stage -- adult stage "female fertile,viable,female semi-sterile" FBgn0069963 CG41049 http://flybase.net/reports/FBgn0069963.html FBan0041049 protein_coding_gene 16-Dec-15 2015_12 FBgn0051140 CG31140 http://flybase.net/reports/FBgn0051140.html "FBgn0039133, FBgn0039134, FBgn0051452" protein_coding_gene "0019992=diacylglycerol binding, 0004143=diacylglycerol kinase activity" "0007205=protein kinase C-activating G-protein coupled receptor signaling pathway, 0046331=lateral inhibition, 0016310=phosphorylation, 0070528=protein kinase C signaling, 0007186=G-protein coupled receptor signaling pathway" "0005737=cytoplasm, 0005634=nucleus" "CG5875, CG31452, DGKt, CG13600" "IPR029071=Ubiquitin-related domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000756=Diacylglycerol kinase, accessory domain, IPR000159=Ras-associating (RA) domain, IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR020454=Diacylglycerol/phorbol-ester binding, IPR001206=Diacylglycerol kinase, catalytic domain" CG31140 16-Dec-15 2015_12 WBGene00000958(dgk-1) ENSMUSG00000004815(Dgkq) ENSG00000145214(DGKQ) "viable,lethal,partially lethal - majority die,visible" "chaeta,supernumerary" FBgn0037090 Est-Q Esterase Q http://flybase.net/reports/FBgn0037090.html protein_coding_gene 0052689=carboxylic ester hydrolase activity CG7529 "IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site, IPR029058=Alpha/Beta hydrolase fold" CG7529 16-Dec-15 2015_12 viable FBgn0035914 CG6282 http://flybase.net/reports/FBgn0035914.html protein_coding_gene "0016627=oxidoreductase activity, acting on the CH-CH group of donors" 0006629=lipid metabolic process "0005737=cytoplasm, 0016021=integral component of membrane" "IPR001104=3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal, IPR010721=Protein of unknown function DUF1295" CG6282 16-Dec-15 2015_12 ENSDARG00000017811(si:ch211-210c8.6) ENSXETG00000013385() viable FBgn0000495 drg dregs http://flybase.net/reports/FBgn0000495.html gene 0001700=embryonic development via the syncytial blastoderm dreg 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,embryonic head" FBgn0036289 CG10657 http://flybase.net/reports/FBgn0036289.html FBgn0043794 protein_coding_gene "0016918=retinal binding, 0005215=transporter activity" "0046331=lateral inhibition, 0006810=transport" 0005622=intracellular "retinaldehyde-binding related protein, BEST:LD32330" "IPR011074=CRAL/TRIO, N-terminal domain, IPR001251=CRAL-TRIO lipid binding domain, IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport" CG10657 16-Dec-15 2015_12 "ENSDARG00000053122(si:ch211-199i15.4),ENSDARG00000045808(rlbp1b),ENSDARG00000012504(rlbp1a)" "ENSXETG00000021635(CLVS1),ENSXETG00000023298(RLBP1L2)" "ENSMUSG00000041216(Clvs1),ENSMUSG00000019785(Clvs2),ENSMUSG00000039194(Rlbp1)" "ENSG00000177182(CLVS1),ENSG00000146352(CLVS2),ENSG00000140522(RLBP1)" "viable,fertile,visible" "chaeta,trichogen cell" FBgn0067054 R13 R13 http://flybase.net/reports/FBgn0067054.html gene 16-Dec-15 2015_12 "partially lethal - majority die,eye color defective,lethal,viable" "eye,pigment cell" FBgn0060589 l(3)S093614 lethal (3) S093614 http://flybase.net/reports/FBgn0060589.html gene 0936/14 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0086243 grk::CHOp24 http://flybase.net/reports/FBgn0086243.html engineered_fusion_gene Grk-Emp 16-Dec-15 2015_12 FBgn0005060 fs(2)OW106 female sterile (2) OW106 http://flybase.net/reports/FBgn0005060.html gene 16-Dec-15 2015_12 FBgn0038326 CG5044 http://flybase.net/reports/FBgn0038326.html protein_coding_gene 0003860=3-hydroxyisobutyryl-CoA hydrolase activity 1903035=negative regulation of response to wounding "HIBCH, CT16187" IPR029045=ClpP/crotonase-like domain CG5044 16-Dec-15 2015_12 ENSDARG00000054867(hibch) YDR036C(EHD3) WBGene00017301(F09F7.4) ENSXETG00000015247(hibch) ENSMUSG00000041426(Hibch) ENSG00000198130(HIBCH) viable DRSC15705 E 0.151093013 0.74816046 -1.475587046 1.511774336 0.747955593 -0.305713664 FBgn0031976 CG7367 http://flybase.net/reports/FBgn0031976.html protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" "0006909=phagocytosis, 0016042=lipid catabolic process" TL "IPR000734=Triacylglycerol lipase family, IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold" CG7367 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0028154 l(3)S042420 lethal (3) S042420 http://flybase.net/reports/FBgn0028154.html gene 0424/20 16-Dec-15 2015_12 "lethal,recessive" FBgn0004989 c(1)a crossover suppressor on 1 http://flybase.net/reports/FBgn0004989.html gene crossover suppressor for chromosome 1 16-Dec-15 2015_12 meiotic cell cycle defective FBgn0262726 T:SS-nec Signal sequence of nec http://flybase.net/reports/FBgn0262726.html engineered_tag "necrotic secretion signal sequence, T:nec" 16-Dec-15 2015_12 FBgn0040970 CG15492 http://flybase.net/reports/FBgn0040970.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053387 5SrRNA:CR33387 5SrRNA:CR33387 http://flybase.net/reports/FBgn0053387.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33387 CR33387 16-Dec-15 2015_12 FBgn0020586 anon-57Ck anon-57Ck http://flybase.net/reports/FBgn0020586.html gene unnamed 16-Dec-15 2015_12 FBgn0003872 ttx tetrodotoxin-sensitive http://flybase.net/reports/FBgn0003872.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0031169 CG1494 http://flybase.net/reports/FBgn0031169.html protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" 0006810=transport 0043190=ATP-binding cassette (ABC) transporter complex "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR026082=ABC transporter A, ABCA" CG1494 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0085696 CG41566 http://flybase.net/reports/FBgn0085696.html FBan0041566 protein_coding_gene 16-Dec-15 2015_12 FBgn0019822 eK6 eK6 http://flybase.net/reports/FBgn0019822.html gene 0001745=compound eye morphogenesis 16-Dec-15 2015_12 FBgn0261395 Prosë±3T "Proteasome ë±3 subunit, Testis-specific" http://flybase.net/reports/FBgn0261395.html "FBgn0039819, FBgn0041192" protein_coding_gene 0004298=threonine-type endopeptidase activity 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0001673=male germ cell nucleus, 0019773=proteasome core complex, alpha-subunit complex" "prosalpha3T, Pros20S-alpha3t, Prosalpha3T, Proteasome alpha3T subunit, :Prosalpha3T, 20s proteasome, alpha3T, Proteasome 20S alpha3t subunit, CG1736, 20S proteasome" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR023332=Proteasome A-type subunit, IPR001353=Proteasome, subunit alpha/beta" CG1736 16-Dec-15 2015_12 YGR135W(PRE9) ENSXETG00000008877(psma4) FBgn0016930 Dyrk2 Dual-specificity tyrosine phosphorylation-regulated kinase 2 http://flybase.net/reports/FBgn0016930.html FBgn0027884 protein_coding_gene "0016740=transferase activity, 0004713=protein tyrosine kinase activity, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0042048=olfactory behavior, 0007608=sensory perception of smell, 0009416=response to light stimulus" 0005829=cytosol "smi35A, BG:DS01523.3, Dyrk2, dDYRK2, DYRK2, CG4551, Dual specificity tyrosine phosphorylation-regulated kinase, Dm2, DmDyrk2, DYRK, smell impaired 35A" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site" CG4551 16-Dec-15 2015_12 ENSDARG00000070734(dyrk4) YJL141C(YAK1) WBGene00003150(mbk-2) "ENSXETG00000023677(dyrk3),ENSXETG00000007333(DYRK2)" ENSMUSG00000030345(Dyrk4) ENSG00000010219(DYRK4) "viable,smell perception defective,neurophysiology defective,size defective,fertile,visible,behavior defective,recessive,chemosensitive behavior defective" "eye,interommatidial bristle,ectopic,supernumerary,ommatidium | adult stage,retina | pupal stage,tertiary pigment cell,ectopic | pupal stage,secondary pigment cell,cone cell,wing" FBgn0267099 CR45539 http://flybase.net/reports/FBgn0267099.html non_protein_coding_gene CR45539 16-Dec-15 2015_12 FBgn0011883 tRNA:I:49Fc transfer RNA:ile:49Fc http://flybase.net/reports/FBgn0011883.html "FBgn0003788, FBgn0050245, FBgn0050521, FBgn0060198" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033433=AUU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30521, tRNA:ile:49Fc, chr2R.trna20-IleAAT, tRNA[Ile], CR30245, tRNA:I:AAT:AE002787-d, ile-c, AE002787.trna38-IleAAT" CR30521 16-Dec-15 2015_12 FBgn0264941 CR44110 http://flybase.net/reports/FBgn0264941.html non_protein_coding_gene lincRNA.995 CR44110 16-Dec-15 2015_12 FBgn0014116 anon-93Fa anon-93Fa http://flybase.net/reports/FBgn0014116.html gene c159 16-Dec-15 2015_12 FBgn0001475 l(1)9Ee lethal (1) 9Ee http://flybase.net/reports/FBgn0001475.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0017364 l(3)89Br lethal (3) 89Br http://flybase.net/reports/FBgn0017364.html gene l(3)89Bp 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority live" "adult abdomen,wing" FBgn0015884 anon-64Bf anon-64Bf http://flybase.net/reports/FBgn0015884.html gene 16-Dec-15 2015_12 adult stage " antenna

, adult head

, leg

" FBgn0040682 CG14664 http://flybase.net/reports/FBgn0040682.html protein_coding_gene FBgn0040682 CG14664 16-Dec-15 2015_12 FBgn0085681 CG41549 http://flybase.net/reports/FBgn0085681.html FBan0041549 protein_coding_gene 16-Dec-15 2015_12 FBgn0022732 l(2)GPMG-18 lethal (2) GPMG-18 http://flybase.net/reports/FBgn0022732.html gene GPMG-18 16-Dec-15 2015_12 "lethal,recessive" FBgn0034364 CG5493 http://flybase.net/reports/FBgn0034364.html protein_coding_gene "0005506=iron ion binding, 0017172=cysteine dioxygenase activity" "0046439=L-cysteine metabolic process, 0055114=oxidation-reduction process" "IPR010300=Cysteine dioxygenase type I, IPR011051=RmlC-like cupin domain, IPR014710=RmlC-like jelly roll fold" CG5493 16-Dec-15 2015_12 ENSDARG00000043036 WBGene00018986(cdo-1) ENSXETG00000018739(cdo1) ENSMUSG00000033022(Cdo1) ENSG00000129596(CDO1) FBgn0011935 tRNA:N5:42Ae transfer RNA:asn5:42Ae http://flybase.net/reports/FBgn0011935.html "FBgn0003759, FBgn0050318, FBgn0050519, FBgn0060133" tRNA_gene "0033442=AAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:asn5:42Ae, chr2R.trna92-AsnGTT, tRNA:N:GTT:AE002769-a, AE002769.trna1-AsnGTT, CR30318, CR30519" CR30519 16-Dec-15 2015_12 FBgn0020903 Su(osk)2-O26 Suppressor of oskar 2-O26 http://flybase.net/reports/FBgn0020903.html gene O26 16-Dec-15 2015_12 FBgn0001061 Fs(3)Pal Female sterile (3) Palat http://flybase.net/reports/FBgn0001061.html gene "Fs(3)Palat, Fs(3)Sz19" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,maternal effect" FBgn0002824 ms(2)E3 male sterile (2) E3 http://flybase.net/reports/FBgn0002824.html gene ms2.3 16-Dec-15 2015_12 "male sterile,recessive" FBgn0027317 l(1)G0076 lethal (1) G0076 http://flybase.net/reports/FBgn0027317.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022219 l(2)k03501 lethal (2) k03501 http://flybase.net/reports/FBgn0022219.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010047 Hdl "Haplo-, diplo-lethal" http://flybase.net/reports/FBgn0010047.html gene Haplo-diplo lethal 16-Dec-15 2015_12 FBgn0061501 l(2)44Fo lethal (2) 44Fo http://flybase.net/reports/FBgn0061501.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039935 CG11224 http://flybase.net/reports/FBgn0039935.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065342 l(2)SH1833 lethal (2) SH1833 http://flybase.net/reports/FBgn0065342.html gene l(2)SH2 1833 16-Dec-15 2015_12 "lethal,recessive" FBgn0003137 Ppn Papilin http://flybase.net/reports/FBgn0003137.html "FBgn0039586, FBgn0039587, FBgn0053103" protein_coding_gene "0004867=serine-type endopeptidase inhibitor activity, 0008270=zinc ion binding, 0004222=metalloendopeptidase activity, 0005201=extracellular matrix structural constituent" 0030198=extracellular matrix organization "0005578=proteinaceous extracellular matrix, 0005604=basement membrane" "CG33103, CG1540, lacunin, CT3186, CG18436, Papilin precursor, lacunin-like, papilin, CT41988, ppl, ppn" "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR010909=PLAC, IPR013098=Immunoglobulin I-set, IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR010294=ADAM-TS Spacer 1, IPR013273=Peptidase M12B, ADAM-TS, IPR003598=Immunoglobulin subtype 2, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR008197=WAP-type 'four-disulfide core' domain" CG33103 16-Dec-15 2015_12 WBGene00016498 ENSG00000100767(PAPLN) "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,Malpighian tubule,embryonic/larval tracheal system" FBgn0002910 mw mottler of white http://flybase.net/reports/FBgn0002910.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0032256 RluA-2 RluA-2 http://flybase.net/reports/FBgn0032256.html protein_coding_gene "0009982=pseudouridine synthase activity, 0043723=2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity, 0003723=RNA binding" "0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response, 0001522=pseudouridine synthesis" "CG6187, yumo" "IPR020103=Pseudouridine synthase, catalytic domain, IPR006224=Pseudouridine synthase, RluC/RluD, conserved site, IPR002942=RNA-binding S4 domain, IPR006225=Pseudouridine synthase, RluC/RluD, IPR006145=Pseudouridine synthase, RsuA/RluB/C/D/E/F" CG6187 16-Dec-15 2015_12 ENSDARG00000060992(LOC565088) "YOL066C(RIB2),YDL036C(PUS9)" WBGene00019498(K07E8.7) ENSXETG00000015973(RPUSD2) ENSMUSG00000027324(Rpusd2) ENSG00000166133(RPUSD2) viable FBgn0261516 Sdic Sperm-specific dynein intermediate chain http://flybase.net/reports/FBgn0261516.html FBgn0025801 protein_coding_gene "0003774=motor activity, 0008017=microtubule binding, 0042623=ATPase activity, coupled" 0007018=microtubule-based movement "0030286=dynein complex, 0005858=axonemal dynein complex" "unnamed, sperm-specific dynein intermediate polypeptide chain" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR025956=Cytoplasmic dynein 1 intermediate chain 1/2" 16-Dec-15 2015_12 FBgn0267055 CR45499 http://flybase.net/reports/FBgn0267055.html pseudogene_attribute CR45499 16-Dec-15 2015_12 FBgn0267869 CR46157 http://flybase.net/reports/FBgn0267869.html pseudogene_attribute ade5-related CR46157 16-Dec-15 2015_12 FBgn0043470 ëÈTry ëÈTry http://flybase.net/reports/FBgn0043470.html FBgn0033619 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "lambdaTrypsin, lambdaTry, CG12350, SP76" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG12350 16-Dec-15 2015_12 "ENSDARG00000012860(tmprss4b),ENSDARG00000006693(tmprss4a)" viable FBgn0024789 Doc\gag gag http://flybase.net/reports/FBgn0024789.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "Doc ORF1, ORF1" "IPR001878=Zinc finger, CCHC-type, IPR006579=Pre-C2HC domain" 16-Dec-15 2015_12 FBgn0034021 CG8180 http://flybase.net/reports/FBgn0034021.html protein_coding_gene IPR002172=Low-density lipoprotein (LDL) receptor class A repeat CG8180 16-Dec-15 2015_12 viable DRSC07093 I -1.794501295 -0.396226069 -1.124513814 -0.668566947 0.508126096 1.180300476 FBgn0065630 l(2)SH0783 lethal (2) SH0783 http://flybase.net/reports/FBgn0065630.html gene l(2)SH2 0783 16-Dec-15 2015_12 "lethal,recessive" FBgn0262471 EP1504 http://flybase.net/reports/FBgn0262471.html gene 16-Dec-15 2015_12 FBgn0265916 CR44705 http://flybase.net/reports/FBgn0265916.html non_protein_coding_gene lincRNA.1014 CR44705 16-Dec-15 2015_12 FBgn0034870 CG13559 http://flybase.net/reports/FBgn0034870.html protein_coding_gene 0035208=positive regulation of hemocyte proliferation "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR006629=LPS-induced tumour necrosis factor alpha factor" CG13559 16-Dec-15 2015_12 viable FBgn0069966 CG41041 http://flybase.net/reports/FBgn0069966.html protein_coding_gene 16-Dec-15 2015_12 FBgn0051253 CG31253 http://flybase.net/reports/FBgn0051253.html FBgn0064878 protein_coding_gene BcDNA:RE50074 CG31253 16-Dec-15 2015_12 FBgn0028962 Aats-ala-m mitochondrial alanyl-tRNA synthetase http://flybase.net/reports/FBgn0028962.html protein_coding_gene "0003676=nucleic acid binding, 0004813=alanine-tRNA ligase activity, 0005524=ATP binding" 0006419=alanyl-tRNA aminoacylation 0005739=mitochondrion "CG4633, Dm mt AlaRS, AlaS" "IPR018165=Alanyl-tRNA synthetase, class IIc, core domain, IPR018164=Alanyl-tRNA synthetase, class IIc, N-terminal, IPR023033=Alanine-tRNA ligase, eukaryota/bacteria, IPR018162=Alanine-tRNA ligase, class IIc, anti-codon-binding domain, IPR002318=Alanine-tRNA ligase, class IIc, IPR009000=Translation protein, beta-barrel domain, IPR018163=Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR012947=Threonyl/alanyl tRNA synthetase, SAD" CG4633 16-Dec-15 2015_12 ENSXETG00000000001(AARS2) "viable,visible,planar polarity defective" trichogen cell FBgn0266985 CR45436 http://flybase.net/reports/FBgn0266985.html non_protein_coding_gene CR45436 16-Dec-15 2015_12 FBgn0000174 ber berrytail http://flybase.net/reports/FBgn0000174.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced,poor" "adult abdomen,wing,genitalia,wing hair,wing vein,anterior scutellar bristle,eye" FBgn0040770 CG12939 http://flybase.net/reports/FBgn0040770.html FBgn0033561 protein_coding_gene CG18354 16-Dec-15 2015_12 FBgn0060569 l(3)S096101 lethal (3) S096101 http://flybase.net/reports/FBgn0060569.html gene 0961/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0004093 l(2)60Da lethal (2) 60Da http://flybase.net/reports/FBgn0004093.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0066351 l(3)99DEd lethal (3) 99DEd http://flybase.net/reports/FBgn0066351.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004815 fs(2)ltoRN73 female sterile (2) ltoRN73 http://flybase.net/reports/FBgn0004815.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0028631 ksh-16 ksh-16 http://flybase.net/reports/FBgn0028631.html gene 16-Dec-15 2015_12 FBgn0260483 CG32714 http://flybase.net/reports/FBgn0260483.html "FBgn0052714, FBgn0030046, FBgn0047087" protein_coding_gene "CG1521, BcDNA:RE56803" 16-Dec-15 2015_12 FBgn0030831 CG12997 http://flybase.net/reports/FBgn0030831.html protein_coding_gene 16-Dec-15 2015_12 FBgn0260051 2L4449 http://flybase.net/reports/FBgn0260051.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0031684 ND-13A NADH dehydrogenase (ubiquinone) 13 kDa A subunit http://flybase.net/reports/FBgn0031684.html protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0005747=mitochondrial respiratory chain complex I "NADH ubiquinone oxidoreductase 13 kDa A, NUMM, NADH-ubiquinone oxidoreductase 13 kDa-A subunit, CG8680, NADH:ubiquinone oxidoreductase 13 kDa A subunit" "IPR019401=Zinc finger, CHCC-type, IPR016668=NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria" CG8680 16-Dec-15 2015_12 ENSDARG00000056583(ndufs6) WBGene00009051(nduf-6) ENSXETG00000008889(NDUFS6) ENSMUSG00000021606(Ndufs6) ENSG00000145494(NDUFS6) "viable,visible" trichogen cell FBgn0053551 tRNA:R:85Cb transfer RNA:arg:85Cb http://flybase.net/reports/FBgn0053551.html "FBgn0003756, FBgn0011947, FBgn0011967, FBgn0051444, FBgn0060075" tRNA_gene "0033431=CGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[arg], tRNA-Arg, CR33551, AE002708.trna2-ArgTCG, CR31444, tRNA:R:TCG:AE002708-b, chr3R.trna8-ArgTCG, tRNA:arg85Cb, tRNA:R1, transfer RNA:arg1, tRNA:arg1" CR33551 16-Dec-15 2015_12 FBgn0022334 f4 f4 http://flybase.net/reports/FBgn0022334.html gene 0007140=male meiosis 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" "spermatocyte,primary spermatocyte cyst" FBgn0046114 Gclm Glutamate-cysteine ligase modifier subunit http://flybase.net/reports/FBgn0046114.html FBgn0039001 protein_coding_gene "0019899=enzyme binding, 0030234=enzyme regulator activity, 0035226=glutamate-cysteine ligase catalytic subunit binding" "0006974=cellular response to DNA damage stimulus, 0035229=positive regulation of glutamate-cysteine ligase activity, 0048149=behavioral response to ethanol, 0008355=olfactory learning, 0007616=long-term memory, 0071722=detoxification of arsenic-containing substance, 0007611=learning or memory, 0006750=glutathione biosynthetic process" "0017109=glutamate-cysteine ligase complex, 0005829=cytosol" "unnamed, Gcsl, DmGCSl, gamma-Glutamylcysteine synthetase regulatory subunit, 4919, box, GCSl, GCLm, DmGCLM, GCLM, CG4919, gclm" IPR023210=NADP-dependent oxidoreductase domain CG4919 16-Dec-15 2015_12 ENSDARG00000018953(gclm) WBGene00017084(E01A2.1) ENSXETG00000008224(gclm) ENSMUSG00000028124(Gclm) ENSG00000023909(GCLM) "viable,fertile,memory defective,chemical sensitive" FBgn0000206 boss bride of sevenless http://flybase.net/reports/FBgn0000206.html "FBgn0024699, FBgn0024700" protein_coding_gene "0005118=sevenless binding, 0030297=transmembrane receptor protein tyrosine kinase activator activity, 0005102=receptor binding, 0004888=transmembrane signaling receptor activity, 0004930=G-protein coupled receptor activity" "0007601=visual perception, 0055088=lipid homeostasis, 0007165=signal transduction, 0007465=R7 cell fate commitment, 0045466=R7 cell differentiation, 0045500=sevenless signaling pathway, 0048749=compound eye development, 0045470=R8 cell-mediated photoreceptor organization, 0009749=response to glucose, 0007186=G-protein coupled receptor signaling pathway, 0042593=glucose homeostasis, 0050730=regulation of peptidyl-tyrosine phosphorylation, 0045467=R7 cell development" "0005886=plasma membrane, 0005771=multivesicular body, 0016021=integral component of membrane, 0005887=integral component of plasma membrane, 0031528=microvillus membrane" "BOSS, Bos, Bride of Sevenless, F transcript, Boss, CG8285, F, Bride of sevenless, X55887" "IPR002956=Bride of sevenless protein, IPR017978=GPCR, family 3, C-terminal" CG8285 16-Dec-15 2015_12 "ENSG00000013588(GPRC5A),ENSG00000111291(GPRC5D),ENSG00000170412(GPRC5C),ENSG00000167191(GPRC5B)" " larval stage , adult stage " " imaginal disc

, adult head

" " larval stage , larval stage | third instar , pupal stage ," " ventral thoracic disc

, photoreceptor cell R1 && photoreceptor cell R3 && photoreceptor cell R4 && photoreceptor cell R6 && photoreceptor cell R7

, retina

, ocellus

, morphogenetic furrow | posterior

, eye-antennal disc

, cone cell

, photoreceptor cell R1--8

, morphogenetic furrow | anterior

, photoreceptor cell R8 | presumptive

, mystery cell

" "viable,visible,lethal,recessive,wild-type,small body,stress response defective" "photoreceptor cell R7,ectopic,eye,embryonic/larval oenocyte" DRSC16916 K 0.164044398 0.535942943 0.088379514 0.061172234 0.257120177 -1.643773927 FBgn0065210 l(2)SH2262 lethal (2) SH2262 http://flybase.net/reports/FBgn0065210.html gene l(2)SH2 2262 16-Dec-15 2015_12 "lethal,recessive" FBgn0060459 l(3)S117708b lethal (3) S117708b http://flybase.net/reports/FBgn0060459.html gene 1177/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0062268 Limbr1 Limbr1 http://flybase.net/reports/FBgn0062268.html gene D-Limbr1 16-Dec-15 2015_12 FBgn0032253 LManI Lysosomal ë±-mannosidase I http://flybase.net/reports/FBgn0032253.html protein_coding_gene "0030246=carbohydrate binding, 0008270=zinc ion binding, 0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, 0004559=alpha-mannosidase activity" 0006013=mannose metabolic process 0005764=lysosome "LManI, CG5322" "IPR000602=Glycoside hydrolase family 38, N-terminal domain, IPR027291=Glycoside hydrolase 38/57, N-terminal domain, IPR028995=Glycoside hydrolase, families 57/38, central domain, IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR011682=Glycosyl hydrolase family 38, C-terminal, IPR015341=Glycoside hydrolase, family 38, central domain, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR011013=Galactose mutarotase-like domain" CG5322 16-Dec-15 2015_12 WBGene00018877(aman-1) ENSXETG00000011609(MAN2B2) ENSMUSG00000005142(Man2b1) ENSG00000104774(MAN2B1) "viable,fertile" FBgn0267347 squ squash http://flybase.net/reports/FBgn0267347.html "FBgn0002652, FBgn0032594, FBgn0069054, FBgn0020558" protein_coding_gene "0048477=oogenesis, 0031047=gene silencing by RNA, 0046843=dorsal appendage formation" 0043186=P granule "adjacent-to-grapes, mat(2)cell-A, SQU, atg, mat(2)cellHK35, Squash, CG4711" CG4711 16-Dec-15 2015_12 FBgn0004404 RpS14b Ribosomal protein S14b http://flybase.net/reports/FBgn0004404.html "FBgn0002585, FBgn0025283, FBgn0025314, FBgn0025318, FBgn0025321, FBgn0029982" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "S14, anon-EST:Posey154, anon-EST:Posey115, RPS14B, S14b, anon-EST:Posey131, RpS14B, RpS14, rpS14B, anon-EST:Posey77, CG1527" "IPR018102=Ribosomal S11, conserved site, IPR001971=Ribosomal protein S11" CG1527 16-Dec-15 2015_12 ENSDARG00000036629(rps14) "YJL191W(RPS14B),YCR031C(RPS14A)" WBGene00004483(rps-14) ENSXETG00000015815(RPS14) "ENSMUSG00000024608(Rps14),ENSMUSG00000061848(Gm5805)" ENSG00000164587(RPS14) DRSC18711 EK 0.349278098 0.264528208 4.689497469 -2.682965472 1.54500985 2.59026072 FBgn0039623 CG1951 http://flybase.net/reports/FBgn0039623.html protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0032504=multicellular organism reproduction" "IPR011009=Protein kinase-like domain, IPR016024=Armadillo-type fold, IPR000719=Protein kinase domain, IPR011989=Armadillo-like helical" CG1951 16-Dec-15 2015_12 "ENSDARG00000069255,ENSDARG00000032627(si:ch211-244b2.1)" YGL083W(SCY1) WBGene00022635(ZC581.9) ENSXETG00000006690(SCYL2) ENSMUSG00000069539(Scyl2) ENSG00000136021(SCYL2) viable FBgn0030595 CG14406 http://flybase.net/reports/FBgn0030595.html protein_coding_gene CG14406 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0035279 Cpr62Ba Cuticular protein 62Ba http://flybase.net/reports/FBgn0035279.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr62Ba, CG13934" IPR000618=Insect cuticle protein CG13934 16-Dec-15 2015_12 viable FBgn0262403 mir-278 mir-278 stem loop http://flybase.net/reports/FBgn0262403.html "FBgn0086369, FBgn0082178, FBgn0043373, FBgn0043361, FBgn0262238" miRNA_gene "0043066=negative regulation of apoptotic process, 0048132=female germ-line stem cell asymmetric division" "mir-278, micro RNA hidden in a nirvana, CR33589, EP2316, EP1229, dme-mir-278, CR42945, EP(2)1229, dme-miR-278, mirvana, Mir-278, miR-278" CR42945 16-Dec-15 2015_12 FBgn0266991 CR45442 http://flybase.net/reports/FBgn0266991.html non_protein_coding_gene CR45672 CR45442 16-Dec-15 2015_12 FBgn0039929 CG11076 http://flybase.net/reports/FBgn0039929.html protein_coding_gene CG11076 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0002862 Mst87F Male-specific RNA 87F http://flybase.net/reports/FBgn0002862.html FBgn0046285 protein_coding_gene 0005198=structural molecule activity 0007283=spermatogenesis 0036126=sperm flagellum "mst(3)gl-9, mst87F, mst-9, BEST:GH23081, mst(3)gl9, bs35f12.y1, CG17956, Mst, mst(3)87F" CG17956 16-Dec-15 2015_12 FBgn0030374 CG15734 http://flybase.net/reports/FBgn0030374.html protein_coding_gene "IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG15734 16-Dec-15 2015_12 viable FBgn0037312 CG11999 http://flybase.net/reports/FBgn0037312.html FBgn0046257 protein_coding_gene "0012505=endomembrane system, 0016020=membrane" "CG-11999, BEST:LD29996" "IPR016093=MIR motif, IPR027005=Glycosyltransferase 39-like" CG11999 16-Dec-15 2015_12 "ENSDARG00000035631(sdf2l1),ENSDARG00000024026(sdf2)" WBGene00020038(R12E2.13) "ENSXETG00000027007(sdf2),ENSXETG00000018564(sdf2l1)" "ENSMUSG00000002064(Sdf2),ENSMUSG00000022769(Sdf2l1)" "ENSG00000132581(SDF2),ENSG00000128228(SDF2L1)" "viable,fertile" FBgn0004233 l(3)93Bg lethal (3) 93Bg http://flybase.net/reports/FBgn0004233.html gene rlr5 16-Dec-15 2015_12 "lethal,recessive" FBgn0065899 l(2)SH0203 lethal (2) SH0203 http://flybase.net/reports/FBgn0065899.html gene l(2)SH2 0203 16-Dec-15 2015_12 "lethal,recessive" FBgn0035132 mthl10 methuselah-like 10 http://flybase.net/reports/FBgn0035132.html "FBgn0046574, FBgn0046575" protein_coding_gene 0004930=G-protein coupled receptor activity "0042594=response to starvation, 0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan" 0016021=integral component of membrane "anon-WO0170980.167, mthl-10, mth-like 10, Mth-like 10, anon-WO0170980.166, CG17061, mth2" "IPR010596=Methuselah, N-terminal domain, IPR023311=Methuselah ectodomain, domain 2, IPR000832=GPCR, family 2, secretin-like, IPR017981=GPCR, family 2-like" CG17061 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" FBgn0084654 l(3)S135703 l(3)S135703 http://flybase.net/reports/FBgn0084654.html gene 16-Dec-15 2015_12 FBgn0051223 CG31223 http://flybase.net/reports/FBgn0051223.html FBgn0038831 protein_coding_gene 0022008=neurogenesis CG15694 CG31223 16-Dec-15 2015_12 ENSXETG00000023323(znhit2) ENSG00000174276(ZNHIT2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0267272 CR45708 http://flybase.net/reports/FBgn0267272.html non_protein_coding_gene CR45708 16-Dec-15 2015_12 FBgn0085326 CG34297 http://flybase.net/reports/FBgn0085326.html protein_coding_gene "IPR019734=Tetratricopeptide repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG34297 16-Dec-15 2015_12 WBGene00016375(C33H5.8) FBgn0029518 CG13376 http://flybase.net/reports/FBgn0029518.html protein_coding_gene CG13376 16-Dec-15 2015_12 FBgn0063918 Max-element\gag-pol gag-pol http://flybase.net/reports/FBgn0063918.html transposable_element_gene "0003676=nucleic acid binding, 0004190=aspartic-type endopeptidase activity, 0008270=zinc ion binding" "0006508=proteolysis, 0015074=DNA integration" "IPR012337=Ribonuclease H-like domain, IPR001995=Peptidase A2A, retrovirus, catalytic, IPR001584=Integrase, catalytic core, IPR005312=Protein of unknown function DUF1759, IPR001878=Zinc finger, CCHC-type, IPR008042=Retrotransposon, Pao, IPR008737=Peptidase aspartic, putative, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0264306 BG01402 http://flybase.net/reports/FBgn0264306.html gene 0002121=inter-male aggressive behavior 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0032449 CG17036 http://flybase.net/reports/FBgn0032449.html protein_coding_gene 0008518=reduced folate carrier activity 0006810=transport 0005886=plasma membrane "IPR020846=Major facilitator superfamily domain, IPR002666=Reduced folate carrier" CG17036 16-Dec-15 2015_12 "ENSDARG00000059712(LOC100329244),ENSDARG00000061103(slc19a3),ENSDARG00000006447(LOC557854)" "WBGene00018138(folt-2),WBGene00044738(folt-3)" "ENSXETG00000002422(SLC19A2),ENSXETG00000008390(TGas049p21.1),ENSXETG00000014773(BC075531.1),ENSXETG00000011482(SLC19A1)" "ENSMUSG00000038496(Slc19a3),ENSMUSG00000040918(Slc19a2)" "ENSG00000117479(SLC19A2),ENSG00000135917(SLC19A3),ENSG00000173638(SLC19A1)" viable FBgn0267517 5.8SrRNA-ë¬:CR45857 5.8S ribosomal RNA pseudogene:CR45857 http://flybase.net/reports/FBgn0267517.html pseudogene_attribute CR45857 CR45857 16-Dec-15 2015_12 FBgn0011623 l(2)rot lethal (2) relative of tid http://flybase.net/reports/FBgn0011623.html gene "1(2)rot, relative of 1(2)tid" 16-Dec-15 2015_12 FBgn0260039 siren3 siren 3 http://flybase.net/reports/FBgn0260039.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0029005 limber limber http://flybase.net/reports/FBgn0029005.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 dendrite | dorsal | embryonic stage FBgn0267595 CR45933 http://flybase.net/reports/FBgn0267595.html pseudogene_attribute CG40948 CR45933 16-Dec-15 2015_12 FBgn0033266 Socs44A Suppressor of Cytokine Signaling at 44A http://flybase.net/reports/FBgn0033266.html protein_coding_gene "0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0046426=negative regulation of JAK-STAT cascade" "dmSocs44A, Socs44E, Socs44a, SOCS, socs44A, CG2160, Suppressor of Cytokine Signaling at 44E, SOCS44A, Suppressor of Cytokine Signaling at 44a, socs42A" "IPR001496=SOCS box domain, IPR028413=Suppressor of cytokine signalling, IPR000980=SH2 domain" CG2160 16-Dec-15 2015_12 "ENSDARG00000060316(cish),ENSDARG00000016773(socs8),ENSDARG00000045557(socs2),ENSDARG00000025428(socs3a),ENSDARG00000026611(socs3b)" "ENSXETG00000022744(socs5),ENSXETG00000012209(socs4)" "ENSMUSG00000037104(Socs5),ENSMUSG00000048379(Socs4)" "ENSG00000120833(SOCS2),ENSG00000114737(CISH),ENSG00000184557(SOCS3),ENSG00000185338(SOCS1)" "visible,viable,fertile" "wing vein L3,wing vein,ectopic" FBgn0028070 l(3)S090302 lethal (3) S090302 http://flybase.net/reports/FBgn0028070.html gene 0903/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0065452 l(2)SH1397 lethal (2) SH1397 http://flybase.net/reports/FBgn0065452.html gene l(2)SH2 1397 16-Dec-15 2015_12 "lethal,recessive" FBgn0085211 RpS28-like Ribosomal protein S28-like http://flybase.net/reports/FBgn0085211.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0002181=cytoplasmic translation" 0022627=cytosolic small ribosomal subunit CG34182 "IPR012340=Nucleic acid-binding, OB-fold, IPR000289=Ribosomal protein S28e" CG34182 16-Dec-15 2015_12 FBgn0035091 CG3829 http://flybase.net/reports/FBgn0035091.html protein_coding_gene 0005044=scavenger receptor activity "0048102=autophagic cell death, 0007155=cell adhesion, 0006952=defense response, 0035071=salivary gland cell autophagic cell death" "0005887=integral component of plasma membrane, 0016020=membrane" IPR002159=CD36 antigen CG3829 16-Dec-15 2015_12 "WBGene00013039(scav-3),WBGene00013578(scav-2)" viable FBgn0024615 nate not enough anterior extension http://flybase.net/reports/FBgn0024615.html gene 0001746=Bolwig's organ morphogenesis 16-Dec-15 2015_12 viable "Bolwig organ,Bolwig nerve" FBgn0085807 CR41590 http://flybase.net/reports/FBgn0085807.html FBan0041590 rRNA_gene CR41590 16-Dec-15 2015_12 FBgn0045851 l(4)102Fa lethal (4) 102Fa http://flybase.net/reports/FBgn0045851.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264706 CR43975 http://flybase.net/reports/FBgn0264706.html pseudogene_attribute CR43975 16-Dec-15 2015_12 FBgn0002790 Mpe Monoplane http://flybase.net/reports/FBgn0002790.html gene Mpl 16-Dec-15 2015_12 "sterile,semidominant,visible,dominant,viable,poor,flightless,courtship behavior defective" wing FBgn0024202 otb outback http://flybase.net/reports/FBgn0024202.html gene 0007391=dorsal closure 16-Dec-15 2015_12 FBgn0051380 CG31380 http://flybase.net/reports/FBgn0051380.html FBgn0039372 protein_coding_gene CG4964 "IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain" CG31380 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" FBgn0265614 CR44432 http://flybase.net/reports/FBgn0265614.html non_protein_coding_gene CR44432 16-Dec-15 2015_12 FBgn0039019 HP1c Heterochromatin Protein 1c http://flybase.net/reports/FBgn0039019.html protein_coding_gene "0035064=methylated histone binding, 0005515=protein binding, 0003682=chromatin binding" "0031940=positive regulation of chromatin silencing at telomere, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0043234=protein complex, 0005705=polytene chromosome interband, 0000791=euchromatin" "HP1, hp1c, HP1c, Heterochromatin protein 1c, CG6990, HP1C, heterochromatin protein 1c, Hp1c" "IPR016197=Chromo domain-like, IPR023779=Chromo domain, conserved site, IPR023780=Chromo domain, IPR017984=Chromo domain subgroup, IPR008251=Chromo shadow domain, IPR000953=Chromo/chromo shadow domain" CG6990 16-Dec-15 2015_12 WBGene00001995(hpl-1) "viable,fertile" FBgn0060495 l(3)S108116b lethal (3) S108116b http://flybase.net/reports/FBgn0060495.html gene 1081/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0000890 fs(1)M88 female sterile (1) M88 http://flybase.net/reports/FBgn0000890.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0260746 Ect3 Ectoderm-expressed 3 http://flybase.net/reports/FBgn0260746.html "FBgn0037977, FBgn0015349" protein_coding_gene 0004565=beta-galactosidase activity "0035071=salivary gland cell autophagic cell death, 0005975=carbohydrate metabolic process, 0048102=autophagic cell death" 0005764=lysosome "beta-galactosidase, CG3132, anon-87Ag, 87A7-9/8, Beta-galactosidase, Ect3" "IPR031330=Glycoside hydrolase 35, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR019801=Glycoside hydrolase, family 35, conserved site, IPR008979=Galactose-binding domain-like, IPR026283=Beta-galactosidase 1-like, IPR025300=Beta-galactosidase jelly roll domain, IPR017853=Glycoside hydrolase superfamily, IPR001944=Glycoside hydrolase, family 35" CG3132 16-Dec-15 2015_12 "ENSDARG00000036415(glb1),ENSDARG00000029955(glb1l)" "WBGene00011832(T19B10.3),WBGene00019225(H22K11.2)" "ENSXETG00000015609(glb1),ENSXETG00000019291(BC084140.1)" "ENSMUSG00000045594(Glb1),ENSMUSG00000026200" "ENSG00000170266(GLB1),ENSG00000163521(GLB1L)" " pupal stage , embryonic stage | cellular blastoderm " " salivary gland

, dorsal ectoderm anlage | restricted

" DRSC15462 I -0.494737721 2.551120895 -0.537365667 0.17019997 0.668161845 -0.216668487 FBgn0042163 CG18843 http://flybase.net/reports/FBgn0042163.html protein_coding_gene 16-Dec-15 2015_12 FBgn0045843 RacGAP84C Rac GTPase activating protein at 84C http://flybase.net/reports/FBgn0045843.html FBgn0060294 protein_coding_gene "0005096=GTPase activator activity, 0019992=diacylglycerol binding, 0017048=Rho GTPase binding" "0001745=compound eye morphogenesis, 0007266=Rho protein signal transduction, 0007283=spermatogenesis" "GAP84C, P1.7, rnRacGap, RotundRacGAP, rnprot; racGAP, RacGAP84C, RotundRACGAP, rnracGAP, RnRacGAP, rnRacGAP, rnRac-GAP, rotund RacGAP, CG2595, RacGAP(84C), rnracGap, RhoGAP-84C8, rnGAP, rnprot1.7" "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG2595 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,partially,some die during embryonic stage,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "wing,crossvein,ectopic,wing vein,macrochaeta & thorax,abdomen,dorsal closure embryo,embryonic/first instar larval cuticle,eye,embryonic epidermis,ventral,embryonic leading edge cell,embryonic leading edge cell & actin filamentptc-559.1,ommatidium,retina,eye photoreceptor cell" FBgn0030563 ë_NACtes2 http://flybase.net/reports/FBgn0030563.html protein_coding_gene CG18157 IPR002715=Nascent polypeptide-associated complex NAC domain CG18157 16-Dec-15 2015_12 FBgn0031618 CG11931 http://flybase.net/reports/FBgn0031618.html protein_coding_gene 16-Dec-15 2015_12 FBgn0041588 eIF2D eukaryotic translation initiation factor 2D http://flybase.net/reports/FBgn0041588.html "FBgn0046221, FBgn0051426" protein_coding_gene 0003743=translation initiation factor activity 0006413=translational initiation 0005737=cytoplasm "BcDNA:LD24540, ligatin, CG31426, eIF2D, Ligatin" "IPR004521=Uncharacterised domain CHP00451, IPR003121=SWIB/MDM2 domain, IPR002478=PUA domain, IPR015947=PUA-like domain, IPR001950=Translation initiation factor SUI1" CG31426 16-Dec-15 2015_12 ENSDARG00000012929(lgtn) YDR117C(TMA64) WBGene00016113(C25H3.4) ENSXETG00000023678(lgtn) ENSMUSG00000026427(Lgtn) ENSG00000143486(EIF2D) "viable,fertile" DRSC13916 E 0.074211636 0.271515023 1.572202701 0.301264646 0.184957385 0.209256852 FBgn0013249 E(var)3-14 E(var)3-14 http://flybase.net/reports/FBgn0013249.html gene E-var(3)14 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0010127 l(1)adl2 lethal (1) adult http://flybase.net/reports/FBgn0010127.html gene "adl-2, l(1)adl-2, addB" 16-Dec-15 2015_12 "hypoactive,lethal,heat sensitive,some die during immature adult stage,recessive" FBgn0260464 CG9288 http://flybase.net/reports/FBgn0260464.html FBgn0038182 protein_coding_gene Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_mORF "IPR011053=Single hybrid motif, IPR002930=Glycine cleavage system H-protein" CG9288 16-Dec-15 2015_12 "viable,fertile" FBgn0030439 CG12716 http://flybase.net/reports/FBgn0030439.html protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion IPR002350=Kazal domain CG12716 16-Dec-15 2015_12 viable FBgn0017460 TfIIIC Transcription factor IIIC http://flybase.net/reports/FBgn0017460.html gene 0006383=transcription from RNA polymerase III promoter "IIIC, TFIIIC" 16-Dec-15 2015_12 FBgn0037622 CG8202 http://flybase.net/reports/FBgn0037622.html protein_coding_gene "IPR029705=UPF0505 family, IPR029707=UPF0505, invertebrates/plants" CG8202 16-Dec-15 2015_12 ENSDARG00000020041(zgc:163107) WBGene00017837(F26G1.1) ENSMUSG00000030982(9030624J02Rik) ENSG00000103544(C16orf62) viable FBgn0053252 CG33252 http://flybase.net/reports/FBgn0053252.html protein_coding_gene CG33252 16-Dec-15 2015_12 viable FBgn0069307 X-63-3 X-63-3 http://flybase.net/reports/FBgn0069307.html gene 0007367=segment polarity determination 16-Dec-15 2015_12 "terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0045442 mthl12 methuselah-like 12 http://flybase.net/reports/FBgn0045442.html "FBgn0052853, FBgn0063602" protein_coding_gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan, 0042594=response to starvation" 0016021=integral component of membrane "Mthl12, Mth-like-12, CG32853, Mth-like 12" "IPR017981=GPCR, family 2-like, IPR023311=Methuselah ectodomain, domain 2, IPR010596=Methuselah, N-terminal domain, IPR022343=GCR1-cAMP receptor" CG32853 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" viable FBgn0060804 l(3)S056906 lethal (3) S056906 http://flybase.net/reports/FBgn0060804.html gene 0569/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0259871 Su(Ste):CR42440 Su(Ste):CR42440 http://flybase.net/reports/FBgn0259871.html non_protein_coding_gene CR42440 CR42440 16-Dec-15 2015_12 FBgn0015019 Cctë_ Cctë_ http://flybase.net/reports/FBgn0015019.html protein_coding_gene "0005524=ATP binding, 0042623=ATPase activity, coupled, 0051082=unfolded protein binding" "0007052=mitotic spindle organization, 0006457=protein folding, 0090307=mitotic spindle assembly, 0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" "0005832=chaperonin-containing T-complex, 0005737=cytoplasm, 0005875=microtubule associated complex" "Cct3, predicted gene Y, Y, vine, Cctgamma, cctgamma, TCPG_DROME, Cct-gamma, CCT-gamma protein, CCTgamma-like, TCP-1 Subunit 3gamma, Tcp-1gamma, chaperonin-containing t-complex protein-1 gamma subunit like, CG8977, Tcp1-gamma, Cctg, cctg, Tcp-1-gamma, geneY, cct-gamma" "IPR012719=T-complex protein 1, gamma subunit, IPR002194=Chaperonin TCP-1, conserved site, IPR027413=GroEL-like equatorial domain, IPR027409=GroEL-like apical domain, IPR027410=TCP-1-like chaperonin intermediate domain, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1)" CG8977 16-Dec-15 2015_12 ENSDARG00000016173(cct3) YJL014W(CCT3) WBGene00018782(cct-3) ENSMUSG00000001416(Cct3) ENSG00000163468(CCT3) lethal "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0261847 CG42779 http://flybase.net/reports/FBgn0261847.html protein_coding_gene CG42779 16-Dec-15 2015_12 FBgn0004203 l(3)84Ea lethal (3) 84Ea http://flybase.net/reports/FBgn0004203.html gene 16-Dec-15 2015_12 lethal FBgn0265162 CR44231 http://flybase.net/reports/FBgn0265162.html non_protein_coding_gene CR44231 16-Dec-15 2015_12 FBgn0002734 E(spl)më«-HLH "Enhancer of split më«, helix-loop-helix" http://flybase.net/reports/FBgn0002734.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity, 0043565=sequence-specific DNA binding" "0048749=compound eye development, 0045466=R7 cell differentiation, 0007219=Notch signaling pathway, 0007399=nervous system development, 0045892=negative regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007525=somatic muscle development, 0048052=R1/R6 cell differentiation" 0005634=nucleus "CG8328, E(Spl)-HLH-mdelta, mdelta0.5, E(spl)delta, HLHmC, HLH-mdelta, HLHmdelta, HLHMdelta, md, E(spl) mdelta, mdelta, mC, bHLHc14, split locus enhancer protein mC, E(Spl) HLH-m delta, E(spl) region transcript mdelta, HLHMD, E(spl)mC, E(spl)-mdelta, E(spl)Mdelta, Enhancer of split region transcript HLHmC, E(spl)mdelta" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG8328 16-Dec-15 2015_12 ENSDARG00000014722(her1) "visible,lethal - all die before end of P-stage,some die during pharate adult stage,viable" "scutellar bristle,wing vein,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutum & macrochaetah-1J3,macrochaeta,photoreceptor cell R8,eye,microchaeta,adult thorax,ommatidium,photoreceptor cell R7,ectopic,photoreceptor cell R1,photoreceptor cell R6,trichogen cell" FBgn0015834 Trip1 Trip1 http://flybase.net/reports/FBgn0015834.html protein_coding_gene 0003743=translation initiation factor activity "0006412=translation, 0006413=translational initiation" "0005875=microtubule associated complex, 0005852=eukaryotic translation initiation factor 3 complex, 0005829=cytosol" "eIF3i, eIF-3beta, DmTRIP, CG8882, eIF3-S2" "IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat, IPR027525=Eukaryotic translation initiation factor 3 subunit I, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG8882 16-Dec-15 2015_12 ENSDARG00000017445(eif3s2) YMR146C(TIF34) WBGene00001232(eif-3.I) ENSXETG00000005247(eif3s2) ENSMUSG00000028798(Eif3i) ENSG00000084623(EIF3I) lethal DRSC03464 IE 0.086258597 -2.043262567 0.215513546 -3.301775125 -0.077499966 0.725667591 FBgn0034263 CG10934 http://flybase.net/reports/FBgn0034263.html FBgn0044751 protein_coding_gene anon-WO0140519.130 CG10934 16-Dec-15 2015_12 DRSC06017 K -0.235655961 0.242543662 -1.297166757 0.084469433 -0.323908376 -4.129704198 FBgn0266400 CR45040 http://flybase.net/reports/FBgn0266400.html non_protein_coding_gene lincRNA.856 CR45040 16-Dec-15 2015_12 FBgn0264791 CR44021 http://flybase.net/reports/FBgn0264791.html non_protein_coding_gene CR44021 16-Dec-15 2015_12 FBgn0084018 CG41456 http://flybase.net/reports/FBgn0084018.html FBan0041456 protein_coding_gene 16-Dec-15 2015_12 FBgn0005481 l(1)ts1233 lethal (1) ts1233 http://flybase.net/reports/FBgn0005481.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0036557 mRpS31 mitochondrial ribosomal protein S31 http://flybase.net/reports/FBgn0036557.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "MRP-S31, CG5904, RpS31" IPR026299=Mitochondrial 28S ribosomal protein S31 CG5904 16-Dec-15 2015_12 ENSDARG00000057855(mrps31) ENSXETG00000020699(MRPS31) ENSMUSG00000031533(Mrps31) ENSG00000102738(MRPS31) "viable,visible" trichogen cell FBgn0085767 CR40685 http://flybase.net/reports/FBgn0085767.html FBan0040685 rRNA_gene 16-Dec-15 2015_12 FBgn0263503 CR43492 http://flybase.net/reports/FBgn0263503.html non_protein_coding_gene CR43492 16-Dec-15 2015_12 FBgn0032284 CG7294 http://flybase.net/reports/FBgn0032284.html FBgn0061406 protein_coding_gene BcDNA:RE28280 CG7294 16-Dec-15 2015_12 viable FBgn0061086 l(3)S012124 lethal (3) S012124 http://flybase.net/reports/FBgn0061086.html gene 0121/24 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052819 CG32819 http://flybase.net/reports/FBgn0052819.html protein_coding_gene tektin IPR000435=Tektin CG32819 16-Dec-15 2015_12 ENSDARG00000045038(tekt3) WBGene00019828(R02E12.4) ENSXETG00000019577(tekt3) "ENSMUSG00000042189(Tekt3),ENSMUSG00000039179(Tekt5)" "ENSG00000125409(TEKT3),ENSG00000153060(TEKT5)" FBgn0013439 dsx::ftz dsx::ftz http://flybase.net/reports/FBgn0013439.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0005152 l(2)G93 lethal (2) G93 http://flybase.net/reports/FBgn0005152.html gene 16-Dec-15 2015_12 lethal FBgn0020924 H-39 H-39 http://flybase.net/reports/FBgn0020924.html gene 16-Dec-15 2015_12 FBgn0038183 CG9286 http://flybase.net/reports/FBgn0038183.html protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity IPR025602=BCP1 family CG9286 16-Dec-15 2015_12 ENSDARG00000004948(bccip) WBGene00022851(ZK1127.4) ENSXETG00000025198(bccip) ENSMUSG00000030983(Bccip) ENSG00000107949(BCCIP) "viable,fertile" FBgn0002950 nofA no object fixation A http://flybase.net/reports/FBgn0002950.html gene S100 16-Dec-15 2015_12 behavior defective eye FBgn0085328 CG34299 http://flybase.net/reports/FBgn0085328.html protein_coding_gene CG34299 16-Dec-15 2015_12 FBgn0035043 CG4781 http://flybase.net/reports/FBgn0035043.html protein_coding_gene "4781, CT15357" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG4781 16-Dec-15 2015_12 viable DRSC04488 I 1.59029473 1.21024675 0.731745296 0.384197866 0.644260174 0.659019684 FBgn0038549 CG17802 http://flybase.net/reports/FBgn0038549.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG17802 16-Dec-15 2015_12 WBGene00004335(ref-2) "partially lethal - majority die,some die during pupal stage" FBgn0264649 liquid-filled liquid filled http://flybase.net/reports/FBgn0264649.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0263750 CG43675 http://flybase.net/reports/FBgn0263750.html "FBgn0053936, FBgn0037681, FBgn0053188" protein_coding_gene "CG33936, BcDNA:RE70963, CG33188, CG33187, CG16750, drn, anon-85Da, CG16751, CG33937, CG3393" CG43675 16-Dec-15 2015_12 FBgn0043458 CG12084 http://flybase.net/reports/FBgn0043458.html FBgn0035224 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0051438=regulation of ubiquitin-protein transferase activity 0031462=Cul2-RING ubiquitin ligase complex "LD02105, BEST:LD02105" "IPR000225=Armadillo, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG12084 16-Dec-15 2015_12 ENSDARG00000009257(zgc:77346) WBGene00020762(zer-1) ENSXETG00000012865(ZER1) ENSMUSG00000039686(Zer1) ENSG00000160445(ZER1) "visible,viable" "dorsocentral bristle,scutellar bristle,trichogen cell,thecogen cell,tormogen cell,eye" FBgn0017630 Eig19C Eig19C http://flybase.net/reports/FBgn0017630.html gene "Eig19, Ecdysone-induced gene 19C" 16-Dec-15 2015_12 FBgn0044096 E(rst)D160 E(rst)D160 http://flybase.net/reports/FBgn0044096.html gene 0001745=compound eye morphogenesis D160 16-Dec-15 2015_12 FBgn0026267 ap::Lim3 ap::Lim3 http://flybase.net/reports/FBgn0026267.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0011367 l(3)j4D1 lethal (3) j4D1 http://flybase.net/reports/FBgn0011367.html FBgn0011384 gene l(3)j5D1 16-Dec-15 2015_12 "lethal,recessive" FBgn0034974 CG16786 http://flybase.net/reports/FBgn0034974.html protein_coding_gene CG16786 16-Dec-15 2015_12 viable FBgn0032258 CG7456 http://flybase.net/reports/FBgn0032258.html protein_coding_gene 0005515=protein binding 0007030=Golgi organization 0017119=Golgi transport complex "IPR013167=Conserved oligomeric Golgi complex, subunit 4" CG7456 16-Dec-15 2015_12 ENSDARG00000054264(zgc:136860) YPR105C(COG4) WBGene00021784(cogc-4) ENSXETG00000015847(COG4) ENSMUSG00000031753(Cog4) ENSG00000103051(COG4) FBgn0060697 l(3)S072517b lethal (3) S072517b http://flybase.net/reports/FBgn0060697.html gene 0725/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0086323 JV47 http://flybase.net/reports/FBgn0086323.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0020870 anon-Q212 anon-Q212 http://flybase.net/reports/FBgn0020870.html gene 2-Q212 16-Dec-15 2015_12 "fertile,chemical sensitive,recessive" FBgn0027096 A45 A45 http://flybase.net/reports/FBgn0027096.html gene 16-Dec-15 2015_12 FBgn0028060 l(3)S093411 lethal (3) S093411 http://flybase.net/reports/FBgn0028060.html gene 0934/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0011720 TA7-1a TA7-1a http://flybase.net/reports/FBgn0011720.html gene 16-Dec-15 2015_12 FBgn0021584 DdbP3 Damage-specific DNA-binding protein 3 http://flybase.net/reports/FBgn0021584.html gene 0003684=damaged DNA binding 0005634=nucleus D-DDB P3 16-Dec-15 2015_12 FBgn0014299 l(3)64Bj lethal (3) 64Bj http://flybase.net/reports/FBgn0014299.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267545 CR45885 http://flybase.net/reports/FBgn0267545.html non_protein_coding_gene CR45885 16-Dec-15 2015_12 FBgn0267539 CR45879 http://flybase.net/reports/FBgn0267539.html non_protein_coding_gene CR45879 16-Dec-15 2015_12 FBgn0259367 EP-439 http://flybase.net/reports/FBgn0259367.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0052548 CG32548 http://flybase.net/reports/FBgn0052548.html "FBgn0030920, FBgn0040881, FBgn0044538" protein_coding_gene "anon-WO0140519.88, CG15051, CG6306" CG32548 16-Dec-15 2015_12 viable DRSC19627 IK 0.362626637 1.586092267 1.146392202 0.373259188 2.196985735 0.224353377 FBgn0001931 l(2)25Ed lethal (2) 25Ed http://flybase.net/reports/FBgn0001931.html gene "l(2)gdh-8, jf28, l(2)jf28, l(2)gdh8" 16-Dec-15 2015_12 "lethal,recessive" FBgn0034471 Obp56e Odorant-binding protein 56e http://flybase.net/reports/FBgn0034471.html protein_coding_gene 0005549=odorant binding "0032504=multicellular organism reproduction, 0007606=sensory perception of chemical stimulus" "0005576=extracellular region, 0005615=extracellular space" "56e, DmelObp56e, CG8462, Odorant binding protein 56e, obp56e" IPR006170=Pheromone/general odorant binding protein CG8462 16-Dec-15 2015_12 "behavior defective,viable" FBgn0005385 rsd raised http://flybase.net/reports/FBgn0005385.html gene 0030047=actin modification "modification, mod" 16-Dec-15 2015_12 "flightless,dominant,cold sensitive,visible,recessive,courtship behavior defective,male,flight defective" wing FBgn0052813 CG32813 http://flybase.net/reports/FBgn0052813.html "FBgn0029576, FBgn0040894, FBgn0045875" protein_coding_gene "CG11446, CG14771, anon-WO0153538.75" IPR028002=Myb/SANT-like DNA-binding domain CG32813 16-Dec-15 2015_12 ENSXETG00000013983(TNeu005j19.1) "viable,fertile" "embryonic/larval hemocyte | third instar larval stage,lamellocyte | third instar larval stage" FBgn0025621 CG16989 http://flybase.net/reports/FBgn0025621.html protein_coding_gene EG:34F3.4 "IPR011989=Armadillo-like helical, IPR025283=Domain of unknown function DUF4042, IPR016024=Armadillo-type fold" CG16989 16-Dec-15 2015_12 ENSXETG00000007964(HEATR6) ENSMUSG00000000976(Heatr6) ENSG00000068097(HEATR6) viable FBgn0052657 CR32657 http://flybase.net/reports/FBgn0052657.html FBgn0046287 non_protein_coding_gene BEST:GH20356 CR32657 16-Dec-15 2015_12 FBgn0031530 pgant2 polypeptide GalNAc transferase 2 http://flybase.net/reports/FBgn0031530.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process 0005795=Golgi stack "unnamed, PGANT2, CG3254" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR001173=Glycosyltransferase 2-like, IPR000772=Ricin B, lectin domain" CG3254 16-Dec-15 2015_12 ENSDARG00000003829(si:dkey-162b3.1) WBGene00001629(gly-4) ENSXETG00000023332(GALNT2) ENSMUSG00000031977 ENSG00000143641(GALNT2) viable FBgn0264776 CG44014 http://flybase.net/reports/FBgn0264776.html FBgn0038346 protein_coding_gene CG14872 "IPR011038=Calycin-like, IPR012674=Calycin" CG44014 16-Dec-15 2015_12 viable FBgn0259325 C277 http://flybase.net/reports/FBgn0259325.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing" FBgn0043481 l(3)66EFe lethal (3) 66EFe http://flybase.net/reports/FBgn0043481.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065917 l(2)SH0167 lethal (2) SH0167 http://flybase.net/reports/FBgn0065917.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039565 CG4884 http://flybase.net/reports/FBgn0039565.html protein_coding_gene 0003723=RNA binding IPR002942=RNA-binding S4 domain CG4884 16-Dec-15 2015_12 ENSXETG00000019267(C6orf203) ENSMUSG00000019797(1700021F05Rik) ENSG00000130349(C6orf203) viable FBgn0003931 snRNA:U4:38AB small nuclear RNA U4 at 38AB http://flybase.net/reports/FBgn0003931.html FBgn0003929 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005687=U4 snRNP "CR32879, U4 small nuclear RNA, U4-38AB, U4:38AB, small nuclear RNA U4, U4-1, K3, 38A U4, snRNA:U4:40AB, U4snRNA, U4 snRNA, dU4, U4-2, U4-38A, snRNA:U4, U4snRNA40AB, chr2L:19806693..19806927, U4" CR32879 16-Dec-15 2015_12 FBgn0031844 CG13771 http://flybase.net/reports/FBgn0031844.html protein_coding_gene 0047617=acyl-CoA hydrolase activity IPR029069=HotDog domain CG13771 16-Dec-15 2015_12 "ENSDARG00000058352(acot9),ENSDARG00000058390(zgc:123262)" "WBGene00019015(F57F4.1),WBGene00020311(T07D3.9)" ENSXETG00000006223(ACOT9) "ENSMUSG00000025287(Acot9),ENSMUSG00000047565(Acot10)" ENSG00000123130(ACOT9) viable FBgn0034722 Rtf1 Rtf1 http://flybase.net/reports/FBgn0034722.html protein_coding_gene 0003677=DNA binding "0051571=positive regulation of histone H3-K4 methylation, 0045893=positive regulation of transcription, DNA-templated, 0006368=transcription elongation from RNA polymerase II promoter, 0006352=DNA-templated transcription, initiation, 0045747=positive regulation of Notch signaling pathway" "0035327=transcriptionally active chromatin, 0016593=Cdc73/Paf1 complex, 0005634=nucleus" "CG10955, dRtf1" "IPR031102=RNA polymerase-associated protein Rtf1, IPR004343=Plus-3 domain, IPR018144=Plus-3 domain, subgroup" CG10955 16-Dec-15 2015_12 ENSDARG00000008947(rtf1) WBGene00009103(F25B3.6) ENSXETG00000017903(BC076973.1) ENSMUSG00000027304(Rtf1) ENSG00000137815(RTF1) "lethal - all die before end of pupal stage,some die during pupal stage,viable,temperature conditional,visible,partially lethal - majority die" "wing,mesothoracic tergum" DRSC04085 I -0.954981181 2.250319973 1.215004919 0.446577289 0.203364778 1.37106682 FBgn0065879 l(2)SH0238 lethal (2) SH0238 http://flybase.net/reports/FBgn0065879.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001690 l(1)ESHS11 lethal (1) ESHS11 http://flybase.net/reports/FBgn0001690.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014301 l(3)7-8 lethal (3) 7-8 http://flybase.net/reports/FBgn0014301.html gene 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0051221 CG31221 http://flybase.net/reports/FBgn0051221.html "FBgn0027710, FBgn0038707, FBgn0040570, FBgn0064956" protein_coding_gene 0030228=lipoprotein particle receptor activity "CG11625, anon-EST:Posey251, CG7237, BcDNA:GH25289" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG31221 16-Dec-15 2015_12 WBGene00010290(F58H1.7) "viable,fertile" FBgn0001836 l(1)ts613 lethal (1) ts613 http://flybase.net/reports/FBgn0001836.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0010848 l(3)04713 lethal (3) 04713 http://flybase.net/reports/FBgn0010848.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive,visible" wing FBgn0001133 grau grauzone http://flybase.net/reports/FBgn0001133.html "FBgn0034571, FBgn0053133" protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000987=core promoter proximal region sequence-specific DNA binding" "0007343=egg activation, 0007143=female meiotic division, 0007349=cellularization, 0007279=pole cell formation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0045143=homologous chromosome segregation, 0006357=regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG3282, CG33133, Grauzone" "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG33133 16-Dec-15 2015_12 " adult stage | male , adult stage && oogenesis stage , adult stage | female , embryonic stage--pupal stage " ovary

" adult stage && oogenesis stage , oogenesis stage | stage S1-10B && adult stage | female " " follicle cell

, nurse cell

, ovary

, germarium

" "female sterile,recessive,meiotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,lethal,partially,partially lethal - majority die,some die during pupal stage" pole cell DRSC04691 E -0.101847388 -0.919589448 -3.90744993 -0.576881711 -0.621854505 0.108150322 FBgn0010590 Prosë_1 Proteasome ë_1 subunit http://flybase.net/reports/FBgn0010590.html FBgn0034064 protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0019774=proteasome core complex, beta-subunit complex, 0005839=proteasome core complex, 0000502=proteasome complex" "beta1, l(2)05070, prosbeta1, CG8392, 8392, lethal (2) 05070, Beta-1, 1(2)05070, Prosbeta1, beta-1" "IPR000243=Peptidase T1A, proteasome beta-subunit, IPR001353=Proteasome, subunit alpha/beta, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR023333=Proteasome B-type subunit, IPR016050=Proteasome beta-type subunit, conserved site" CG8392 16-Dec-15 2015_12 ENSDARG00000002240(psmb6) YJL001W(PRE3) WBGene00003947(pbs-1) ENSXETG00000026029(psmb9) "ENSMUSG00000018286(Psmb6),ENSMUSG00000024337(Psmb9)" ENSG00000142507(PSMB6) "lethal,recessive" DRSC07159 IEK -1.639963265 -2.125326226 -2.902983217 -3.388561255 -0.323908376 -4.129704198 FBgn0037059 CG10510 http://flybase.net/reports/FBgn0037059.html protein_coding_gene CG10510 16-Dec-15 2015_12 viable DRSC11614 I 1.725416842 -0.234737116 -0.524937808 -0.464230522 -0.296325743 0.054704433 FBgn0034472 CG8517 http://flybase.net/reports/FBgn0034472.html protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" "0006974=cellular response to DNA damage stimulus, 0006662=glycerol ether metabolic process, 0045454=cell redox homeostasis" 0005739=mitochondrion "mtr, 8517, thioredoxin" "IPR005746=Thioredoxin, IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG8517 16-Dec-15 2015_12 ENSDARG00000034777(zgc:77127) WBGene00007099(trx-2) ENSXETG00000000246(txn2) ENSMUSG00000005354(Txn2) ENSG00000100348(TXN2) viable DRSC07205 E -0.024693221 0.767235203 -1.631516982 -0.2398146 1.106853669 0.287317181 FBgn0004443 prd10 paired-like 10 http://flybase.net/reports/FBgn0004443.html gene PRD gene 10 16-Dec-15 2015_12 embryonic stage | early FBgn0021975 l(2)k09927 lethal (2) k09927 http://flybase.net/reports/FBgn0021975.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262588 CG43125 http://flybase.net/reports/FBgn0262588.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan" CG43125 16-Dec-15 2015_12 FBgn0052707 APC4 Anaphase Promoting Complex subunit 4 http://flybase.net/reports/FBgn0052707.html FBgn0030083 protein_coding_gene 0004842=ubiquitin-protein transferase activity "0030071=regulation of mitotic metaphase/anaphase transition, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process" 0005680=anaphase-promoting complex "CG32707, Anaphase Promoting Complex 4, CG4350" "IPR024977=Anaphase-promoting complex subunit 4, WD40 domain, IPR017169=Anaphase-promoting complex subunit 4, metazoa, IPR024789=Anaphase-promoting complex subunit 4, IPR024790=Anaphase-promoting complex subunit 4 long domain, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG32707 16-Dec-15 2015_12 ENSDARG00000032237(zgc:101872) ENSXETG00000000957(ANAPC4) ENSMUSG00000029176(Anapc4) ENSG00000053900(ANAPC4) "viable,visible" "trichogen cell,tormogen cell" FBgn0031542 CG15414 http://flybase.net/reports/FBgn0031542.html protein_coding_gene CG15414 16-Dec-15 2015_12 viable DRSC00429 K -0.43623813 0.489870477 0.478888065 -0.22614717 1.704886919 0.552620098 FBgn0004949 amy amethyst http://flybase.net/reports/FBgn0004949.html gene 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0061480 somatostatin somatostatin http://flybase.net/reports/FBgn0061480.html gene 0005184=neuropeptide hormone activity "somatostatin-like, SS" 16-Dec-15 2015_12 FBgn0025885 Inos Inos http://flybase.net/reports/FBgn0025885.html FBgn0033176 protein_coding_gene 0004512=inositol-3-phosphate synthase activity "0006021=inositol biosynthetic process, 0008654=phospholipid biosynthetic process" 0005737=cytoplasm "bs36h12.y1, INOS, myo-inositol-1-phosphate-synthase, CG11143" "IPR002587=Myo-inositol-1-phosphate synthase, IPR013021=Myo-inositol-1-phosphate synthase, GAPDH-like, IPR016040=NAD(P)-binding domain" CG11143 16-Dec-15 2015_12 YJL153C(INO1) WBGene00012148(VF13D12L.1) ENSXETG00000022938(ISYNA1) ENSMUSG00000019139(Isyna1) ENSG00000105655(ISYNA1) viable FBgn0014914 anon-4Fh anon-4Fh http://flybase.net/reports/FBgn0014914.html gene 16-Dec-15 2015_12 FBgn0265732 CR44539 http://flybase.net/reports/FBgn0265732.html non_protein_coding_gene CR44539 16-Dec-15 2015_12 FBgn0260862 Vti1a Vesicle transport through interaction with t-SNAREs 1a http://flybase.net/reports/FBgn0260862.html "FBgn0044803, FBgn0035156" protein_coding_gene 0005484=SNAP receptor activity "0006906=vesicle fusion, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport" "0030173=integral component of Golgi membrane, 0031201=SNARE complex" "CG3279, Vti1, VTI1 ortholog (S. cerevisiae), VTI1, Vti1a" "IPR007705=Vesicle transport v-SNARE, N-terminal, IPR010989=t-SNARE, IPR027027=GOSR2/Membrin/Bos1" CG3279 16-Dec-15 2015_12 ENSDARG00000045065(vti1a) YMR197C(VTI1) WBGene00013302(vti-1) ENSXETG00000025900(vti1b) ENSMUSG00000024983(Vti1a) ENSG00000151532(VTI1A) DRSC08563 I -0.532764176 2.111289253 -0.281285637 -0.936740179 0.770927513 -0.396170296 FBgn0003162 Pu Punch http://flybase.net/reports/FBgn0003162.html protein_coding_gene "0060308=GTP cyclohydrolase I regulator activity, 0003934=GTP cyclohydrolase I activity" "2000274=regulation of epithelial cell migration, open tracheal system, 0048067=cuticle pigmentation, 0046654=tetrahydrofolate biosynthetic process, 0008363=larval chitin-based cuticle development, 0043095=regulation of GTP cyclohydrolase I activity, 0035185=preblastoderm mitotic cell cycle, 0048072=compound eye pigmentation, 0006728=pteridine biosynthetic process, 0009880=embryonic pattern specification, 0006729=tetrahydrobiopterin biosynthetic process" 0005737=cytoplasm "l(2)57Cf, GTP cyclohydrolase, Gr, GCH1, Grape, GTPC, CG9441, DGTPCH, GTP cyclohydrolase I isoform c, GTP cyclohydrolase I, p[Gr], GTPCH, unpigmented, punch, upi" "IPR018234=GTP cyclohydrolase I, conserved site, IPR001474=GTP cyclohydrolase I, IPR020602=GTP cyclohydrolase I domain" CG9441 16-Dec-15 2015_12 "ENSDARG00000070453(zgc:195269),ENSDARG00000013340(gch2)" YGR267C(FOL2) WBGene00000298(cat-4) ENSXETG00000012214(Q6DIE0_XENTR) ENSMUSG00000037580(Gch1) ENSG00000131979(GCH1) embryonic stage | early organism

"sterile,lethal,recessive,eye color defective,viable,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,rescuable maternal effect,partially,poor,body color defective" "pigment cell,macrochaeta,eye,trident,embryonic/first instar larval cuticle,cuticle,head,nucleus | embryonic stage 4,nuclear chromosome | embryonic stage 4,chromatin | embryonic stage 4,extended germ band embryo,pole cell,embryonic/larval dorsal trunk,embryonic/larval tracheal system,wing,cephalopharyngeal skeleton" FBgn0026777 Rad23 Rad23 http://flybase.net/reports/FBgn0026777.html protein_coding_gene 0003684=damaged DNA binding "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006289=nucleotide-excision repair" "0005634=nucleus, 0005737=cytoplasm" "rad23, RAD23, CG1836, DHR23" "IPR029071=Ubiquitin-related domain, IPR015360=XPC-binding domain, IPR009060=UBA-like, IPR000626=Ubiquitin domain, IPR006636=Heat shock chaperonin-binding, IPR015940=Ubiquitin-associated domain, IPR004806=UV excision repair protein Rad23" CG1836 16-Dec-15 2015_12 "ENSDARG00000021550(rad23b),ENSDARG00000058984(zgc:123349),ENSDARG00000020001(rad23a)" YEL037C(RAD23) WBGene00013924(rad-23) ENSXETG00000005751(rad23b) "ENSMUSG00000028426(Rad23b),ENSMUSG00000003813(Rad23a)" "ENSG00000119318(RAD23B),ENSG00000179262(RAD23A)" viable FBgn0039026 CG7029 http://flybase.net/reports/FBgn0039026.html protein_coding_gene 0008157=protein phosphatase 1 binding CG7029 16-Dec-15 2015_12 viable DRSC16177 E -0.296893218 -0.159975559 -1.056713404 1.515975083 0.360864618 0.742387924 FBgn0031324 CG14342 http://flybase.net/reports/FBgn0031324.html protein_coding_gene CG14342 16-Dec-15 2015_12 viable DRSC00372 IE 0.085131312 -4.555334239 -0.50539243 -2.27714765 1.383548247 -1.487996887 FBgn0029689 CG6428 http://flybase.net/reports/FBgn0029689.html protein_coding_gene "0004622=lysophospholipase activity, 0004067=asparaginase activity" 0006520=cellular amino acid metabolic process CG-6428 "IPR006033=L-asparaginase, type I, IPR006034=Asparaginase/glutaminase, IPR027473=L-asparaginase, C-terminal domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR027474=L-asparaginase, N-terminal, IPR020827=Asparaginase/glutaminase, active site 1, IPR027475=Asparaginase/glutaminase, active site 2" CG6428 16-Dec-15 2015_12 ENSDARG00000052942(zgc:171644) WBGene00007756(C27A7.5) ENSXETG00000023076(ASPG) ENSMUSG00000037686(Aspg) ENSG00000166183(ASPG) "viable,fertile" FBgn0262364 CG43062 http://flybase.net/reports/FBgn0262364.html protein_coding_gene CG43062 16-Dec-15 2015_12 FBgn0011125 l(1)Q87 lethal (1) Q87 http://flybase.net/reports/FBgn0011125.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0034202 CG17287 http://flybase.net/reports/FBgn0034202.html protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0008270=zinc ion binding" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17287 16-Dec-15 2015_12 YNL326C(PFA3) FBgn0005708 l(1)TK111 lethal (1) TK111 http://flybase.net/reports/FBgn0005708.html gene l111 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0050048 CG30048 http://flybase.net/reports/FBgn0050048.html protein_coding_gene "IPR001024=PLAT/LH2 domain, IPR002859=PKD/REJ-like domain, IPR014010=REJ domain" CG30048 16-Dec-15 2015_12 viable FBgn0000295 Cg9E Collagen-like 9E http://flybase.net/reports/FBgn0000295.html gene "DCg9, Cg9" 16-Dec-15 2015_12 FBgn0065921 l(2)SH0154 lethal (2) SH0154 http://flybase.net/reports/FBgn0065921.html gene l(2)SH2 0154 16-Dec-15 2015_12 "lethal,recessive" FBgn0267262 CR45698 http://flybase.net/reports/FBgn0267262.html non_protein_coding_gene CR45698 16-Dec-15 2015_12 FBgn0039465 Tsp97E Tetraspanin 97E http://flybase.net/reports/FBgn0039465.html protein_coding_gene 0016021=integral component of membrane "Tspan31, CG6323, Dm.Tsp97E" "IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG6323 16-Dec-15 2015_12 "ENSDARG00000021970,ENSDARG00000070479(tspan13b),ENSDARG00000068883(tspan13a)" "ENSXETG00000009659(sas),ENSXETG00000022794(tspan13)" "ENSMUSG00000020577(Tspan13),ENSMUSG00000006736(Tspan31)" "ENSG00000106537(TSPAN13),ENSG00000135452(TSPAN31)" viable FBgn0002897 mus211 mutagen-sensitive 211 http://flybase.net/reports/FBgn0002897.html gene 16-Dec-15 2015_12 "chemical sensitive,radiation sensitive,viable,fertile" FBgn0023008 l(3)S104101 lethal (3) S104101 http://flybase.net/reports/FBgn0023008.html gene "unnamed, 1041/01, 1041/1" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0052191 CG32191 http://flybase.net/reports/FBgn0052191.html FBgn0036755 protein_coding_gene 0003943=N-acetylgalactosamine-4-sulfatase activity 0008152=metabolic process CG5584 "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR000917=Sulfatase, IPR017850=Alkaline-phosphatase-like, core domain, IPR024607=Sulfatase, conserved site" CG32191 16-Dec-15 2015_12 ENSDARG00000063359(LOC563783) WBGene00006310(sul-3) "ENSXETG00000015525(ARSJ),ENSXETG00000000542(ARSB),ENSXETG00000011881(ARSI)" "ENSMUSG00000042082(Arsb),ENSMUSG00000036412(Arsi),ENSMUSG00000046561(Arsj)" "ENSG00000183876(ARSI),ENSG00000113273(ARSB),ENSG00000180801(ARSJ)" viable FBgn0014091 anon-31Eb anonymous at 31E-b http://flybase.net/reports/FBgn0014091.html gene 16-Dec-15 2015_12 FBgn0062640 EP873 EP873 http://flybase.net/reports/FBgn0062640.html gene EP(2)0873 16-Dec-15 2015_12 FBgn0065790 l(2)SH0430 lethal (2) SH0430 http://flybase.net/reports/FBgn0065790.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032407 Pex19 Peroxin 19 http://flybase.net/reports/FBgn0032407.html FBgn0066310 protein_coding_gene "0007399=nervous system development, 0007031=peroxisome organization" 0005777=peroxisome "CG5325, BEST:GH03076, PEX19, Peroxisomal farnesylated protein, DmelPex19, Pex-19" IPR006708=Pex19 protein CG5325 16-Dec-15 2015_12 ENSDARG00000004891(pex19) WBGene00004201(prx-19) ENSXETG00000008120() ENSMUSG00000003464(Pex19) ENSG00000162735(PEX19) viable FBgn0262598 mtsh mitoshell http://flybase.net/reports/FBgn0262598.html "FBgn0064157, FBgn0032019" protein_coding_gene "0010635=regulation of mitochondrial fusion, 0007005=mitochondrion organization, 0007283=spermatogenesis, 0055050=astral spindle assembly involved in male meiosis, 0007112=male meiosis cytokinesis" "mitoshell, CG7795" CG7795 16-Dec-15 2015_12 FBgn0035766 eco Establishment of cohesion http://flybase.net/reports/FBgn0035766.html "FBtr0076882, FBpp0076592" protein_coding_gene "0016407=acetyltransferase activity, 0008080=N-acetyltransferase activity" "0007064=mitotic sister chromatid cohesion, 0016573=histone acetylation, 0007052=mitotic spindle organization" 0000790=nuclear chromatin "eco, ECO, Deco, CG8598, Drosophila eco1, deco, Eco1" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase, IPR028009=N-acetyltransferase ESCO, acetyl-transferase domain, IPR028005=N-acetyltransferase ESCO, zinc-finger" CG8598 16-Dec-15 2015_12 ENSDARG00000014685(esco2) ENSXETG00000020442(ESCO2) "ENSMUSG00000022034(Esco2),ENSMUSG00000024293(Esco1)" ENSG00000171320(ESCO2) "mitotic cell cycle defective,viable,visible" "mitotic cell cycle,mitosis & nuclear chromosome,trichogen cell,mesothoracic tergum" DRSC11006 IE 1.559047661 -0.70971592 1.012590465 -1.536702315 -0.663683118 0.008937135 FBgn0061074 l(3)S016603b lethal (3) S016603b http://flybase.net/reports/FBgn0061074.html gene 0166/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0004869 l(3)62Cb lethal (3) 62Cb http://flybase.net/reports/FBgn0004869.html gene 16-Dec-15 2015_12 lethal FBgn0083113 W7 W7 http://flybase.net/reports/FBgn0083113.html gene 16-Dec-15 2015_12 viable wing FBgn0060968 l(3)S030009 lethal (3) S030009 http://flybase.net/reports/FBgn0060968.html gene 0300/09 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065120 l(3)SH149 lethal (3) SH149 http://flybase.net/reports/FBgn0065120.html gene l(2)SH3 149 16-Dec-15 2015_12 "lethal,recessive" FBgn0082369 EP3281 EP3281 http://flybase.net/reports/FBgn0082369.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0041232 CG32395 http://flybase.net/reports/FBgn0041232.html FBgn0052395 protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "CG32395, Gustatory receptor 65C.1, Gr65a, Gr65C1, GR65C.1, 65C.1" IPR013604=7TM chemoreceptor CG32395 16-Dec-15 2015_12 FBgn0053770 CG33770 http://flybase.net/reports/FBgn0053770.html FBgn0037173 protein_coding_gene CG14458 "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG33770 16-Dec-15 2015_12 viable FBgn0263660 CR43651 http://flybase.net/reports/FBgn0263660.html non_protein_coding_gene pri-mir-14 CR43651 16-Dec-15 2015_12 FBgn0060442 l(3)S123304b lethal (3) S123304b http://flybase.net/reports/FBgn0060442.html gene 1233/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0001379 l(1)2Bk lethal (1) 2Bk http://flybase.net/reports/FBgn0001379.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041742 l(2)44Fq lethal (2) 44Fq http://flybase.net/reports/FBgn0041742.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020331 anon-6A7 anon-6A7 http://flybase.net/reports/FBgn0020331.html gene "6A7, unnamed" 16-Dec-15 2015_12 FBgn0262009 CG42827 http://flybase.net/reports/FBgn0262009.html "FBan0006784, FBgn0039074" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity CG6784 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42827 16-Dec-15 2015_12 viable FBgn0028597 l(2)k05113a lethal (2) k05113a http://flybase.net/reports/FBgn0028597.html gene l(2)k05113 16-Dec-15 2015_12 "lethal,recessive" FBgn0261378 mgg maggot http://flybase.net/reports/FBgn0261378.html gene mgt 16-Dec-15 2015_12 "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "dorsal appendage,ovary" FBgn0041826 KA16-II KA16-II http://flybase.net/reports/FBgn0041826.html gene 16-Dec-15 2015_12 "flightless,recessive" FBgn0260264 GSd222 http://flybase.net/reports/FBgn0260264.html gene 16-Dec-15 2015_12 lethal FBgn0004675 E(A53g) Enhancer of abnormal abdomen-53g http://flybase.net/reports/FBgn0004675.html gene "Enhancer of abnormal abdomen, E(A)" 16-Dec-15 2015_12 FBgn0266933 CR45384 http://flybase.net/reports/FBgn0266933.html non_protein_coding_gene CR45384 16-Dec-15 2015_12 FBgn0260296 GSd421 http://flybase.net/reports/FBgn0260296.html gene 16-Dec-15 2015_12 lethal FBgn0029835 CG5921 http://flybase.net/reports/FBgn0029835.html protein_coding_gene 0030507=spectrin binding 0000086=G2/M transition of mitotic cell cycle 0045177=apical part of cell IPR001478=PDZ domain CG5921 16-Dec-15 2015_12 ENSDARG00000051876(ush1c) ENSMUSG00000030838(Ush1c) ENSG00000006611(USH1C) viable FBgn0042179 CG18869 http://flybase.net/reports/FBgn0042179.html "FBgn0044780, FBgn0045873" protein_coding_gene "0016758=transferase activity, transferring hexosyl groups" 0008152=metabolic process "unnamed, anon-WO0153538.77, anon-WO0140519.104, Tes36" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG18869 16-Dec-15 2015_12 viable FBgn0004981 Bit Bitten http://flybase.net/reports/FBgn0004981.html gene 0007476=imaginal disc-derived wing morphogenesis 16-Dec-15 2015_12 "visible,dominant,lethal,recessive,flight defective" wing FBgn0260029 siren5 siren 5 http://flybase.net/reports/FBgn0260029.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0038260 CG14855 http://flybase.net/reports/FBgn0038260.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain" CG14855 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0032484 kek4 kekkon4 http://flybase.net/reports/FBgn0032484.html protein_coding_gene 0042059=negative regulation of epidermal growth factor receptor signaling pathway 0005887=integral component of plasma membrane "kekkon-like, CG9431, CT26742" "IPR007110=Immunoglobulin-like domain, IPR013151=Immunoglobulin, IPR000483=Cysteine-rich flanking region, C-terminal, IPR001611=Leucine-rich repeat, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG9431 16-Dec-15 2015_12 "ENSDARG00000007856,ENSDARG00000055578(rtn4rl1),ENSDARG00000052012(rtn4rl2a),ENSDARG00000037495(rtn4rl2b),ENSDARG00000025697(rtn4r)" WBGene00021353(Y37E3.13) "ENSXETG00000024115(LRIT3),ENSXETG00000005631(LRIT2)" "ENSMUSG00000035653(Lrfn5),ENSMUSG00000040490(Lrfn2),ENSMUSG00000030600(Lrfn1),ENSMUSG00000036957(Lrfn3),ENSMUSG00000045045(Lrfn4)" ENSG00000177021 "auditory perception defective,viable" FBgn0065469 l(2)SH1335 lethal (2) SH1335 http://flybase.net/reports/FBgn0065469.html gene l(2)SH2 1335 16-Dec-15 2015_12 "lethal,recessive" FBgn0028124 l(3)S058209b lethal (3) S058209b http://flybase.net/reports/FBgn0028124.html gene "l(3)S058209, 0582/09" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0037176 CG14456 http://flybase.net/reports/FBgn0037176.html protein_coding_gene "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG14456 16-Dec-15 2015_12 FBgn0000160 bas bang-sensitive http://flybase.net/reports/FBgn0000160.html gene "0009612=response to mechanical stimulus, 0007638=mechanosensory behavior" bas-A 16-Dec-15 2015_12 "bang sensitive,neurophysiology defective,paralytic,behavior defective,semidominant,heat sensitive,recessive" abdominal 1 dorsal longitudinal muscle FBgn0037578 CG9601 http://flybase.net/reports/FBgn0037578.html protein_coding_gene "28573184, PNKP" "IPR008984=SMAD/FHA domain, IPR013954=Polynucleotide kinase 3 phosphatase, IPR006551=Polynucleotide 3'-phosphatase, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000253=Forkhead-associated (FHA) domain, IPR006549=HAD-superfamily hydrolase,subfamily IIIA, IPR006550=Polynucleotide kinase 3-phosphatase, metazoan, IPR023214=HAD-like domain" CG9601 16-Dec-15 2015_12 ENSDARG00000068521(zgc:153084) WBGene00009010(F21D5.5) ENSMUSG00000002963(Pnkp) ENSG00000039650(PNKP) viable FBgn0011141 l(1)Q217 lethal (1) Q217 http://flybase.net/reports/FBgn0011141.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0267504 28SrRNA:CR45844 28S ribosomal RNA:CR45844 http://flybase.net/reports/FBgn0267504.html rRNA_gene CR45844 CR45844 16-Dec-15 2015_12 FBgn0000762 fs(1)A508 female sterile (1) A508 http://flybase.net/reports/FBgn0000762.html gene fs(1)508 16-Dec-15 2015_12 "female sterile,recessive,visible" "egg,macrochaeta" FBgn0038639 CG7705 http://flybase.net/reports/FBgn0038639.html protein_coding_gene CG7705 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0026755 Ugt37b1 UDP-glycosyltransferase 37b1 http://flybase.net/reports/FBgn0026755.html FBgn0031790 protein_coding_gene "0008194=UDP-glycosyltransferase activity, 0016758=transferase activity, transferring hexosyl groups" 0006011=UDP-glucose metabolic process 0016021=integral component of membrane "CG9481, DmeUgt37b1, AC 005285A" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG9481 16-Dec-15 2015_12 "WBGene00007073(ugt-2),WBGene00007072(ugt-1),WBGene00013903(ugt-3),WBGene00020592(ugt-12),WBGene00020594(ugt-10),WBGene00020593(ugt-11),WBGene00020587(ugt-9),WBGene00019234(ugt-8),WBGene00019232(ugt-13),WBGene00019235(H23N18.4),WBGene00019233(ugt-14)" viable FBgn0265180 CG44245 http://flybase.net/reports/FBgn0265180.html FBgn0034603 protein_coding_gene 0007498=mesoderm development CG9480 CG44245 16-Dec-15 2015_12 FBgn0259520 B2001 http://flybase.net/reports/FBgn0259520.html gene 16-Dec-15 2015_12 visible "tarsal segment,anterior crossvein,wing vein L3,arista" FBgn0032003 CG8349 http://flybase.net/reports/FBgn0032003.html protein_coding_gene "0008270=zinc ion binding, 0004126=cytidine deaminase activity" 0009972=cytidine deamination "IPR002125=Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016192=APOBEC/CMP deaminase, zinc-binding, IPR006263=Cytidine deaminase, homodimeric, IPR016193=Cytidine deaminase-like" CG8349 16-Dec-15 2015_12 YLR245C(CDD1) "WBGene00000392(cdd-2),WBGene00000391(cdd-1)" FBgn0036740 Vps60 Vacuolar protein sorting 60 http://flybase.net/reports/FBgn0036740.html FBgn0023102 protein_coding_gene "0030713=ovarian follicle cell stalk formation, 0032509=endosome transport via multivesicular body sorting pathway, 0046426=negative regulation of JAK-STAT cascade, 0007034=vacuolar transport, 0050680=negative regulation of epithelial cell proliferation, 0045807=positive regulation of endocytosis, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation" 0000815=ESCRT III complex "CG6259, unnamed, Chmp5, anon-74EFb, VPS60, bs36h07.y1" IPR005024=Snf7 family CG6259 16-Dec-15 2015_12 "ENSDARG00000041900(chmp5),ENSDARG00000038855(LOC558613)" YDR486C(VPS60) WBGene00018290(F41E6.9) ENSXETG00000004991(chmp5) ENSMUSG00000028419(Chmp5) ENSG00000086065(CHMP5) "lethal,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage" "epithelium,somatic clone,interfollicle cell,female germline cyst" FBgn0263462 snoRNA:Dek-a http://flybase.net/reports/FBgn0263462.html snoRNA_gene "chr2R:12372273..12372375, snoRNA:dek-a, snoHACA_04" CR43577 16-Dec-15 2015_12 FBgn0030012 CG18262 http://flybase.net/reports/FBgn0030012.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG18262 16-Dec-15 2015_12 FBgn0261400 didy disjunction dysfunction http://flybase.net/reports/FBgn0261400.html protein_coding_gene Disjunction dysfunction 16-Dec-15 2015_12 FBgn0263744 CR43669 http://flybase.net/reports/FBgn0263744.html FBgn0051782 pseudogene_attribute CG31782 CR43669 16-Dec-15 2015_12 FBgn0020501 CU58 Cible d'Ubx 58 http://flybase.net/reports/FBgn0020501.html gene 58 16-Dec-15 2015_12 FBgn0031287 CG4291 http://flybase.net/reports/FBgn0031287.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding, 0017058=FH1 domain binding" "0000398=mRNA splicing, via spliceosome" "0005686=U2 snRNP, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex" "IPR003604=Zinc finger, U1-type, IPR013085=Zinc finger, U1-C type, IPR001202=WW domain, IPR000690=Zinc finger, C2H2-type matrin" CG4291 16-Dec-15 2015_12 WBGene00010159(F56G4.4) ENSXETG00000018896(wbp4) ENSMUSG00000022023(Wbp4) ENSG00000120688(WBP4) viable FBgn0265213 fs(2)Z2-1896 http://flybase.net/reports/FBgn0265213.html gene 16-Dec-15 2015_12 female sterile FBgn0022400 Gase2 Gastric serine protease 2 http://flybase.net/reports/FBgn0022400.html gene 0008236=serine-type peptidase activity 16-Dec-15 2015_12 FBgn0003135 pph polyphenic http://flybase.net/reports/FBgn0003135.html gene "pph-61, polyphene 61" 16-Dec-15 2015_12 "small body,viable,female semi-sterile,recessive" "eye,wing,scutellar bristle" FBgn0020830 l(2)PW8 "Pullman, Washington 8" http://flybase.net/reports/FBgn0020830.html gene 16-Dec-15 2015_12 "partially lethal - majority die,female" FBgn0039776 PH4ë±EFB prolyl-4-hydroxylase-alpha EFB http://flybase.net/reports/FBgn0039776.html "FBgn0039775, FBgn0046215, FBgn0051022" protein_coding_gene "0005506=iron ion binding, 0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0031418=L-ascorbic acid binding" "0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0055114=oxidation-reduction process" "0005783=endoplasmic reticulum, 0012505=endomembrane system, 0016222=procollagen-proline 4-dioxygenase complex" "BcDNA:SD05564, PH4-aEFB, CG31022, propyl-4-hydroxylase-alpha EFB, CG1473, CG12088, PH4alphaEFB, PH4alpha-EFB" "IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG31022 16-Dec-15 2015_12 "ENSDARG00000071700(si:ch211-146f4.5),ENSDARG00000033537(LOC556879),ENSDARG00000071082(p4ha1),ENSDARG00000010085(p4ha2)" "WBGene00004025(phy-2),WBGene00001077(dpy-18)" "ENSXETG00000006154(P4HA1),ENSXETG00000006987(p4ha2)" "ENSMUSG00000019916(P4ha1),ENSMUSG00000018906(P4ha2)" "ENSG00000122884(P4HA1),ENSG00000072682(P4HA2)" "viable,fertile" DRSC14473 K 0.539286455 -0.83753037 0.923775169 0.047495267 -1.611860053 -1.067961506 FBgn0037949 CG17360 http://flybase.net/reports/FBgn0037949.html FBgn0064826 protein_coding_gene BcDNA:RH29885 "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG17360 16-Dec-15 2015_12 ENSG00000116786(PLEKHM2) "viable,fertile" FBgn0041103 nht no hitter http://flybase.net/reports/FBgn0041103.html FBgn0028851 protein_coding_gene "0046982=protein heterodimerization activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" "0010468=regulation of gene expression, 0007283=spermatogenesis, 0006367=transcription initiation from RNA polymerase II promoter" "0001673=male germ cell nucleus, 0005669=transcription factor TFIID complex, 0005730=nucleolus" "BG:DS07851.6, CG15259, TFIID, dmTAF4b, dTAF4L, Nht, nohitter, TAF4, dTAF[[II]]110, DS07851.6" IPR007900=Transcription initiation factor TFIID component TAF4 CG15259 16-Dec-15 2015_12 "male sterile,viable,body color defective" mesothoracic tergum FBgn0053359 5SrRNA:CR33359 5SrRNA:CR33359 http://flybase.net/reports/FBgn0053359.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33359 CR33359 16-Dec-15 2015_12 FBgn0033516 CG12898 http://flybase.net/reports/FBgn0033516.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG12898 16-Dec-15 2015_12 viable FBgn0003087 pim pimples http://flybase.net/reports/FBgn0003087.html protein_coding_gene "0008406=gonad development, 0051298=centrosome duplication, 0002064=epithelial cell development, 0000281=mitotic cytokinesis, 0007443=Malpighian tubule morphogenesis, 0022008=neurogenesis, 0007502=digestive tract mesoderm development, 0007399=nervous system development, 0000070=mitotic sister chromatid segregation, 0051306=mitotic sister chromatid separation" "0005634=nucleus, 0005737=cytoplasm" "Pim, fragmented gonads 2, PIM, PIMPLES, securin, Securin, CG5052, frag2, l(2)31Df" IPR006940=Securin sister-chromatid separation inhibitor CG5052 16-Dec-15 2015_12 " embryonic stage , embryonic stage&&pupal stage&&adult stage , embryonic stage | early , larval stage | third instar " " embryonic central nervous system

,

ubiquitous " "mitotic cell cycle defective,recessive,lethal,wild-type,increased cell death,cytokinesis defective,lethal - all die before end of embryonic stage,some die during embryonic stage,sterile,visible,neuroanatomy defective,viable" "gonad,gonadal sheath proper primordium,visceral mesoderm,embryonic Malpighian tubule,Malpighian tubule,embryonic head,embryonic/first instar larval cuticle,epidermal cell,centrosome,epithelial cell,metaphase plate,mitotic M phasenos.bcd3'UTR.TGCN4,nuclear chromosomenos.bcd3'UTR.TGCN4,mitotic M phaseda.G32,nuclear chromosomeda.G32,eye,ommatidium,wing,metaphase platenos.bcd3'UTR.TGCN4,embryonic/larval neuroblast,ganglion mother cell" DRSC03591 E -0.492675508 -1.179457277 1.667406989 -4.573222412 0.868451076 0.215224666 FBgn0000947 fs(2)A17 female sterile (2) A17 http://flybase.net/reports/FBgn0000947.html gene 16-Dec-15 2015_12 "female sterile,recessive" "egg chamber,ovary,oocyte" FBgn0085729 CG42227 http://flybase.net/reports/FBgn0085729.html FBan0041432 protein_coding_gene 16-Dec-15 2015_12 FBgn0053635 CG33635 http://flybase.net/reports/FBgn0053635.html protein_coding_gene 0042802=identical protein binding 0006895=Golgi to endosome transport "0000139=Golgi membrane, 0016021=integral component of membrane" "unnamed, BP1075, HDC00027" "IPR011691=Vesicle transport protein, SFT2-like, IPR007305=Vesicle transport protein, Got1/SFT2-like" CG33635 16-Dec-15 2015_12 ENSDARG00000070284(sft2d3) YBL102W(SFT2) WBGene00007690(C18E9.10) ENSXETG00000014211(TEgg049d06.1) ENSMUSG00000044982(Sft2d3) ENSG00000173349(SFT2D3) viable FBgn0039309 CG11891 http://flybase.net/reports/FBgn0039309.html "FBgn0053091, FBtr0084818, FBpp0084193, FBtr0084819, FBpp0084194, FBtr0084820, FBpp0084195" protein_coding_gene "CG33091, CT37044" "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG11891 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" FBgn0029120 Su(Sxlfs)46 Su(Sxlfs)46 http://flybase.net/reports/FBgn0029120.html gene 16-Dec-15 2015_12 FBgn0031032 CG14204 http://flybase.net/reports/FBgn0031032.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "0035220=wing disc development, 0022416=chaeta development" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG14204 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" FBgn0283463 mir-997-2 mir-997-2 stem loop http://flybase.net/reports/FBgn0283463.html miRNA_gene "miR-997, dme-mir-997-2, hp-mir-997-2" 16-Dec-15 2015_12 FBgn0028403 Shaq Shaq http://flybase.net/reports/FBgn0028403.html gene 0005643=nuclear pore 16-Dec-15 2015_12 FBgn0022147 l(2)k06019 lethal (2) k06019 http://flybase.net/reports/FBgn0022147.html gene 16-Dec-15 2015_12 "lethal,recessive" crystal cell FBgn0263606 Hsc20 Heat shock protein cognate 20 http://flybase.net/reports/FBgn0263606.html "FBgn0005547, FBgn0085275" protein_coding_gene 0051087=chaperone binding "0051259=protein oligomerization, 0006457=protein folding" 0005739=mitochondrion "lethal (3) 72Do, l(3)72Do, heat shock protein cognate 20, CG34246" "IPR001623=DnaJ domain, IPR004640=Co-chaperone Hsc20, IPR009073=Co-chaperone HscB, C-terminal oligomerisation domain" CG34246 16-Dec-15 2015_12 YGL018C(JAC1) WBGene00001033(dnj-15) ENSXETG00000026948(HSCB) ENSMUSG00000043510(Hscb) ENSG00000100209(HSCB) FBgn0259583 B2029 http://flybase.net/reports/FBgn0259583.html gene 16-Dec-15 2015_12 visible leg FBgn0052724 CR32724 http://flybase.net/reports/FBgn0052724.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0004739 l(3)85Df lethal (3) 85Df http://flybase.net/reports/FBgn0004739.html gene 16-Dec-15 2015_12 lethal FBgn0014205 l(1)16Fl lethal (1) 16Fl http://flybase.net/reports/FBgn0014205.html gene 16-Dec-15 2015_12 "hypoactive,visible,lethal - all die before end of pupal stage,recessive,some die during pupal stage" macrochaeta FBgn0024232 gprs gprs http://flybase.net/reports/FBgn0024232.html FBgn0042196 protein_coding_gene "CG5967, CG18471, Gprs" "IPR000210=BTB/POZ domain, IPR011705=BTB/Kelch-associated, IPR011333=POZ domain" CG18471 16-Dec-15 2015_12 viable FBgn0013555 l(3)ry141 lethal (3) ry141 http://flybase.net/reports/FBgn0013555.html gene l(3)141 16-Dec-15 2015_12 "lethal,recessive" FBgn0054051 CG34051 http://flybase.net/reports/FBgn0054051.html FBgn0082663 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "BP1077, HDC03337, unnamed" CG34051 16-Dec-15 2015_12 FBgn0034564 CG9344 http://flybase.net/reports/FBgn0034564.html FBgn0063016 protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0005688=U6 snRNP, 0005732=small nucleolar ribonucleoprotein complex, 0030532=small nuclear ribonucleoprotein complex" BcDNA:RE43665 "IPR016487=Sm-like protein Lsm6/SmF, IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type" CG9344 16-Dec-15 2015_12 ENSDARG00000036995(lsm6) YDR378C(LSM6) WBGene00003080(lsm-6) ENSXETG00000023683(LSM6) "ENSMUSG00000031683(Lsm6),ENSMUSG00000058567(Gm10043)" ENSG00000164167(LSM6) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0265712 CR44519 http://flybase.net/reports/FBgn0265712.html non_protein_coding_gene CR44519 16-Dec-15 2015_12 FBgn0019684 mle::z mle::z http://flybase.net/reports/FBgn0019684.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 FBgn0010178 tu(2)2 tu(2)2 http://flybase.net/reports/FBgn0010178.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,partially lethal - majority die" FBgn0013554 l(3)ry133 lethal (3) ry133 http://flybase.net/reports/FBgn0013554.html gene l(3)133 16-Dec-15 2015_12 "lethal,recessive" FBgn0034962 MAN1 MAN1 http://flybase.net/reports/FBgn0034962.html FBgn0046220 protein_coding_gene 0030514=negative regulation of BMP signaling pathway "0012505=endomembrane system, 0005639=integral component of nuclear inner membrane" "dMAN1, BcDNA:LD24895, dMan1, CG3167" "IPR003887=LEM domain, IPR011015=LEM/LEM-like domain, IPR018996=Inner nuclear membrane protein MAN1" CG3167 16-Dec-15 2015_12 ENSDARG00000015824(lemd3) ENSXETG00000013841(LEMD3) ENSMUSG00000048661(Lemd3) "ENSG00000174106(LEMD3),ENSG00000161904(LEMD2)" "short lived,male sterile,female semi-sterile,flightless,neuroanatomy defective,locomotor rhythm defective,neurophysiology defective,partially lethal - majority die,some die during pharate adult stage,viable,fertile,lethal,recessive,rescuable maternal effect,visible,locomotor behavior defective,female sterile,partially,some die during pupal stage" "wing vein,ectopic,posterior crossvein,anterior crossvein,wing vein L4,wing blade,wing,testis,ovary" FBgn0054029 CG34029 http://flybase.net/reports/FBgn0054029.html FBgn0082840 protein_coding_gene "unnamed, BP1066" CG34029 16-Dec-15 2015_12 FBgn0045468 Gr93d Gustatory receptor 93d http://flybase.net/reports/FBgn0045468.html "FBgn0041226, FBgn0051335" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "93F.4, GR93d, CG31335, Gustatory receptor 93F.4, Gr93F4, DmGr93d, GR93F.4" IPR013604=7TM chemoreceptor CG31335 16-Dec-15 2015_12 viable embryonic/larval hemocyte | third instar larval stage FBgn0001023 fs(3)A14 female sterile (3) A14 http://flybase.net/reports/FBgn0001023.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0264484 CR43892 http://flybase.net/reports/FBgn0264484.html non_protein_coding_gene CR43892 16-Dec-15 2015_12 FBgn0085210 CG34181 http://flybase.net/reports/FBgn0085210.html protein_coding_gene CG34181 16-Dec-15 2015_12 FBgn0263480 snoRNA:Irbp-a http://flybase.net/reports/FBgn0263480.html snoRNA_gene snoRNA:irbp-a CR43595 16-Dec-15 2015_12 FBgn0267454 CR45804 http://flybase.net/reports/FBgn0267454.html non_protein_coding_gene CR45804 16-Dec-15 2015_12 FBgn0030552 mRpL38 mitochondrial ribosomal protein L38 http://flybase.net/reports/FBgn0030552.html protein_coding_gene "0003735=structural constituent of ribosome, 0008429=phosphatidylethanolamine binding" 0006412=translation 0005762=mitochondrial large ribosomal subunit "mitochondrial ribosomal protein L3a, MRP-L3, mRpL3a, CG15871" IPR008914=Phosphatidylethanolamine-binding protein PEBP CG15871 16-Dec-15 2015_12 ENSDARG00000039667(LOC100334022) WBGene00021327(Y34D9A.1) ENSXETG00000016963(mrpl38) ENSMUSG00000020775(Mrpl38) ENSG00000204316(MRPL38) "viable,visible" trichogen cell FBgn0033762 ZnT49B Zinc transporter 49B http://flybase.net/reports/FBgn0033762.html protein_coding_gene 0008324=cation transmembrane transporter activity "0055085=transmembrane transport, 0006812=cation transport" 0016021=integral component of membrane "CG8632, cg8632, dZnT49B" "IPR009061=Putative DNA-binding domain, IPR002524=Cation efflux protein, IPR022656=XPA C- terminal, IPR027469=Cation efflux protein transmembrane domain" CG8632 16-Dec-15 2015_12 ENSDARG00000057272(slc30a9) WBGene00022174(Y71H2AM.9) ENSXETG00000021074(SLC30A9) ENSMUSG00000029221(Slc30a9) ENSG00000014824(SLC30A9) "viable,visible" trichogen cell FBgn0031459 CG2862 http://flybase.net/reports/FBgn0031459.html protein_coding_gene 0008252=nucleotidase activity "IPR011146=HIT-like domain, IPR019808=Histidine triad, conserved site, IPR001310=Histidine triad (HIT) protein" CG2862 16-Dec-15 2015_12 ENSDARG00000040128(zgc:103764) YDL125C(HNT1) WBGene00009002(hint-1) ENSXETG00000008278(hint1) ENSMUSG00000020267(Hint1) ENSG00000169567(HINT1) DRSC26502 K 0.314245589 -0.868546306 -0.34541095 -0.323914662 0.050671809 -1.944829843 FBgn0028384 cof condensed figures http://flybase.net/reports/FBgn0028384.html gene 16-Dec-15 2015_12 FBgn0036888 CG9330 http://flybase.net/reports/FBgn0036888.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0043190=ATP-binding cassette (ABC) transporter complex "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain" CG9330 16-Dec-15 2015_12 YFR009W(GCN20) WBGene00018339(abcf-3) ENSXETG00000017277(ABCF3) ENSMUSG00000003234(Abcf3) ENSG00000161204(ABCF3) "viable,fertile,visible" trichogen cell FBgn0035960 CG4942 http://flybase.net/reports/FBgn0035960.html protein_coding_gene "0008535=respiratory chain complex IV assembly, 0051205=protein insertion into membrane" "0016021=integral component of membrane, 0005743=mitochondrial inner membrane" IPR001708=Membrane insertase OXA1/ALB3/YidC CG4942 16-Dec-15 2015_12 ENSDARG00000039638(LOC100330020) YGR062C(COX18) WBGene00021932(Y55F3AR.1) ENSXETG00000008131(COX18) ENSMUSG00000035505(Cox18) ENSG00000163626(COX18) viable FBgn0011276 HLH3B Helix loop helix protein 3B http://flybase.net/reports/FBgn0011276.html protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" 0005634=nucleus "CG2655, bHLHa20, HLH3b, EG:155E2.2, DroSCL" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG2655 16-Dec-15 2015_12 " pupal stage , embryonic stage | stage >=8 " ventral midline

viable FBgn0046631 anon-38E.5 anon-38E.5 http://flybase.net/reports/FBgn0046631.html gene 38E.5 16-Dec-15 2015_12 FBgn0022750 anon-D2b anon-D2b http://flybase.net/reports/FBgn0022750.html gene D2 16-Dec-15 2015_12 FBgn0003166 pun puny http://flybase.net/reports/FBgn0003166.html gene 16-Dec-15 2015_12 "male fertile,female fertile,viable,reduced,visible,recessive" "wing,eye" FBgn0038038 CG5167 http://flybase.net/reports/FBgn0038038.html protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process 0005811=lipid particle Saccheropin dehydrogenase "IPR016040=NAD(P)-binding domain, IPR005097=Saccharopine dehydrogenase, NADP binding domain" CG5167 16-Dec-15 2015_12 "ENSDARG00000024564(sccpdhb),ENSDARG00000033665,ENSDARG00000014512" "WBGene00017719(F22F7.1),WBGene00017720(F22F7.2)" ENSXETG00000007895(SCCPDH) ENSMUSG00000038936(Sccpdh) ENSG00000143653(SCCPDH) viable FBgn0034156 CG5348 http://flybase.net/reports/FBgn0034156.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane IPR004837=Sodium/calcium exchanger membrane region CG5348 16-Dec-15 2015_12 "WBGene00003574(ncx-9),WBGene00003573(ncx-8),WBGene00003575(ncx-10),WBGene00003571(ncx-6)" ENSMUSG00000032754(Slc24a6) ENSG00000089060(SLC24A6) "viable,visible" trichogen cell FBgn0060808 l(3)S054910b lethal (3) S054910b http://flybase.net/reports/FBgn0060808.html gene 0549/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0266351 CR45000 http://flybase.net/reports/FBgn0266351.html non_protein_coding_gene CR45000 16-Dec-15 2015_12 FBgn0065503 l(2)SH1202 lethal (2) SH1202 http://flybase.net/reports/FBgn0065503.html gene l(2)SH2 1202 16-Dec-15 2015_12 "lethal,recessive" FBgn0260343 GSd247 http://flybase.net/reports/FBgn0260343.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0267573 CR45913 http://flybase.net/reports/FBgn0267573.html non_protein_coding_gene pri-mir-1002_mir-968 CR45913 16-Dec-15 2015_12 FBgn0039937 fd102C forkhead domain 102C http://flybase.net/reports/FBgn0039937.html protein_coding_gene "0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003690=double-stranded DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding" "0009888=tissue development, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0007389=pattern specification process, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0005667=transcription factor complex, 0005634=nucleus" "fd102C, CG11152, Dmcg11152" "IPR018122=Fork head domain conserved site1, IPR001766=Fork head domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG11152 16-Dec-15 2015_12 "ENSMUSG00000032998(Foxj3),ENSMUSG00000003154(Foxj2)" FBgn0002933 ng1 new glue 1 http://flybase.net/reports/FBgn0002933.html FBgn0010372 protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "CG10781, EG:96G10.5, SC1, ng, new glue protein, nested, new glue, ng-1, ngp" CG10781 16-Dec-15 2015_12 larval stage | third instar FBgn0053129 CG33129 http://flybase.net/reports/FBgn0053129.html "FBgn0032319, FBgn0032320" protein_coding_gene "0012505=endomembrane system, 0005811=lipid particle" "CG6087, CG6089" "IPR019308=Protein of unknown function DUF2359, TMEM214, IPR016024=Armadillo-type fold" CG33129 16-Dec-15 2015_12 ENSMUSG00000038828(Tmem214) ENSG00000119777(TMEM214) "viable,fertile" FBgn0002691 mc microchaetae http://flybase.net/reports/FBgn0002691.html gene "microchaete, tb-53, mc-like" 16-Dec-15 2015_12 "visible,recessive,viable,fertile" "microchaeta & adult thorax,macrochaeta,scutellum & macrochaeta,eye,wing,tergite,female,microchaeta,scutellar bristle,head bristle,wing margin bristle,adult abdomen & sclerite" FBgn0260768 CG42566 http://flybase.net/reports/FBgn0260768.html "FBgn0034760, FBan0013512" protein_coding_gene 0008270=zinc ion binding CG13512 "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase, IPR006629=LPS-induced tumour necrosis factor alpha factor" CG42566 16-Dec-15 2015_12 FBgn0037734 trbd trabid http://flybase.net/reports/FBgn0037734.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 0008270=zinc ion binding" "0070536=protein K63-linked deubiquitination, 0016579=protein deubiquitination, 0030177=positive regulation of Wnt signaling pathway" "0005634=nucleus, 0005737=cytoplasm" "CG9448, unnamed, trbd, Trabid, Q9VH90" "IPR001876=Zinc finger, RanBP2-type, IPR003323=OTU domain" CG9448 16-Dec-15 2015_12 "ENSDARG00000063190(zranb1b),ENSDARG00000060257" ENSXETG00000023629(ZRANB1) ENSMUSG00000030967(Zranb1) ENSG00000019995(ZRANB1) "viable,fertile,locomotor behavior defective,short lived" heart primordium FBgn0262550 Mod(GMroX1)8 http://flybase.net/reports/FBgn0262550.html gene 16-Dec-15 2015_12 FBgn0259434 EP-158 http://flybase.net/reports/FBgn0259434.html gene 16-Dec-15 2015_12 visible wing vein FBgn0044322 jockey\ORF ORF http://flybase.net/reports/FBgn0044322.html transposable_element_gene D-element\ORF 16-Dec-15 2015_12 FBgn0001873 l(1)XN75a lethal (1) XN75a http://flybase.net/reports/FBgn0001873.html gene 16-Dec-15 2015_12 FBgn0265738 CR44545 http://flybase.net/reports/FBgn0265738.html non_protein_coding_gene "incRNA.496, lincRNA.496" CR44545 16-Dec-15 2015_12 FBgn0052056 scramb1 scramblase 1 http://flybase.net/reports/FBgn0052056.html "FBgn0036077, FBtr0076301, FBpp0076030, FBtr0076302, FBpp0076031, FBtr0076303, FBpp0076032" protein_coding_gene 0017128=phospholipid scramblase activity "0007268=synaptic transmission, 0017121=phospholipid scrambling, 0048812=neuron projection morphogenesis" "CG6590, Scramblase, CT20492, Scramb1, CG32056" "IPR025659=Tubby C-terminal-like domain, IPR005552=Scramblase" CG32056 16-Dec-15 2015_12 "ENSDARG00000069432(zgc:77051),ENSDARG00000004514,ENSDARG00000068446(si:ch211-137i24.5)" YJR100C(AIM25) "WBGene00011935(scrm-1),WBGene00014200(scrm-2),WBGene00015437(scrm-3)" "ENSXETG00000015514(),ENSXETG00000001630()" "ENSMUSG00000032369(Plscr1),ENSMUSG00000032372(Plscr2)" "ENSG00000188313(PLSCR1),ENSG00000163746(PLSCR2)" "viable,fertile" DRSC09724 K 0.108980203 -0.493186742 -0.043814901 -0.104756792 -0.019891358 -1.683817184 FBgn0002808 ms(1)401 male sterile (1) 401 http://flybase.net/reports/FBgn0002808.html gene 16-Dec-15 2015_12 "male sterile,recessive" "spermatocyte & nucleus,spermatocyte & nucleolus,Y chromosome loop" FBgn0052827 CG32827 http://flybase.net/reports/FBgn0052827.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019738 l(1)91-3 lethal (1) 91-3 http://flybase.net/reports/FBgn0019738.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0266172 pre-mod(mdg4)-E http://flybase.net/reports/FBgn0266172.html protein_coding_gene CG44878 CG44878 16-Dec-15 2015_12 FBgn0038675 CG6013 http://flybase.net/reports/FBgn0038675.html protein_coding_gene "IPR009071=High mobility group box domain, IPR010422=Coiled-coil domain-containing protein 124/Lso1/Lso2" CG6013 16-Dec-15 2015_12 ENSDARG00000043502(ccdc124) WBGene00022268(Y73E7A.1) ENSXETG00000013543(TTpA004i15.1) ENSMUSG00000007721(Ccdc124) ENSG00000007080(CCDC124) viable FBgn0038080 CG12279 http://flybase.net/reports/FBgn0038080.html FBgn0047005 protein_coding_gene "0004792=thiosulfate sulfurtransferase activity, 0051082=unfolded protein binding" 0006457=protein folding BcDNA:RH54517 "IPR001307=Thiosulphate sulfurtransferase, conserved site, IPR001763=Rhodanese-like domain" CG12279 16-Dec-15 2015_12 ENSDARG00000071567(LOC563265) "YOR286W(RDL2),YOR285W(RDL1)" ENSMUSG00000028251(2610029I01Rik) ENSG00000215845(TSTD1) "viable,fertile" FBgn0021852 l(2)k14601 lethal (2) k14601 http://flybase.net/reports/FBgn0021852.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051068 CG31068 http://flybase.net/reports/FBgn0051068.html FBgn0065019 protein_coding_gene BcDNA:AT10318 CG31068 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0039508 CG3368 http://flybase.net/reports/FBgn0039508.html protein_coding_gene SD09067p "IPR016024=Armadillo-type fold, IPR019442=Domain of unknown function DUF2428, death-receptor-like" CG3368 16-Dec-15 2015_12 viable embryonic/larval hemocyte | third instar larval stage DRSC15485 K 0.486685737 -0.08246026 0.329580723 0.370907528 1.658436237 -0.150253754 FBgn0085600 CG41286 http://flybase.net/reports/FBgn0085600.html FBan0041286 protein_coding_gene 16-Dec-15 2015_12 FBgn0035570 CG13712 http://flybase.net/reports/FBgn0035570.html protein_coding_gene 0032879=regulation of localization HL4 IPR007970=Protein of unknown function DUF733 CG13712 16-Dec-15 2015_12 embryonic stage | embryonic cycle 14 blastoderm embryo | striped

viable FBgn0061031 l(3)S024421 lethal (3) S024421 http://flybase.net/reports/FBgn0061031.html gene 0244/21 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267205 CR45645 http://flybase.net/reports/FBgn0267205.html non_protein_coding_gene CR45645 16-Dec-15 2015_12 FBgn0084024 CG41463 http://flybase.net/reports/FBgn0084024.html FBan0041463 protein_coding_gene 16-Dec-15 2015_12 FBgn0263256 CG43394 http://flybase.net/reports/FBgn0263256.html "FBgn0051607, FBgn0064896, FBgn0051900" protein_coding_gene "BcDNA:RE27850, CG31607, CG31900" CG43394 16-Dec-15 2015_12 DRSC01013 E -1.151415306 -0.448441508 2.779887731 0.921811947 -1.279607288 0.043368998 FBgn0259659 B0183 http://flybase.net/reports/FBgn0259659.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "leg,unguis,arista" FBgn0002341 l(3)87Bj lethal (3) 87Bj http://flybase.net/reports/FBgn0002341.html gene "l(3)ck22, ck22" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0261006 snoRNA:83E4-5 http://flybase.net/reports/FBgn0261006.html snoRNA_gene Dm83E4-5 CR43568 16-Dec-15 2015_12 FBgn0033088 PGAP3 Post-GPI attachment to proteins 3 ortholog (H. sapiens) http://flybase.net/reports/FBgn0033088.html protein_coding_gene "0016788=hydrolase activity, acting on ester bonds" 0006505=GPI anchor metabolic process 0031227=intrinsic component of endoplasmic reticulum membrane CG3271 IPR007217=Per1-like CG3271 16-Dec-15 2015_12 ENSDARG00000057531(zgc:171485) YCR044C(PER1) WBGene00019806(R01B10.4) ENSXETG00000015142(PGAP3) ENSMUSG00000038208(Pgap3) ENSG00000161395(PGAP3) "viable,partially lethal - majority die,some die during pupal stage" FBgn0062568 Mod(var)E226 Mod(var)E226 http://flybase.net/reports/FBgn0062568.html gene 0006342=chromatin silencing E226 16-Dec-15 2015_12 "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0065919 l(2)SH0159 lethal (2) SH0159 http://flybase.net/reports/FBgn0065919.html gene l(2)SH2 0159 16-Dec-15 2015_12 "lethal,recessive" FBgn0011257 ms(2)43C male sterile (2)43C http://flybase.net/reports/FBgn0011257.html gene 0007286=spermatid development 16-Dec-15 2015_12 male sterile "spermatid,Nebenkern" FBgn0044334 682 682 http://flybase.net/reports/FBgn0044334.html gene 0007268=synaptic transmission Line 682 16-Dec-15 2015_12 FBgn0264087 Slob Slowpoke binding protein http://flybase.net/reports/FBgn0264087.html "FBgn0024290, FBgn0031927" protein_coding_gene "0004672=protein kinase activity, 0005515=protein binding" "0006468=protein phosphorylation, 0042594=response to starvation, 0050804=regulation of synaptic transmission, 0042391=regulation of membrane potential, 0007274=neuromuscular synaptic transmission" 0005737=cytoplasm "CG43756, SLOWPOKE-binding protein, giant slob, slob, CG13792, CG6772, SLO-binding protein, Slowpoke channel binding protein" IPR011009=Protein kinase-like domain CG43756 16-Dec-15 2015_12 FBgn0038239 CG14850 http://flybase.net/reports/FBgn0038239.html protein_coding_gene CG14850 16-Dec-15 2015_12 viable FBgn0002934 ni-B nicked of Bridges http://flybase.net/reports/FBgn0002934.html gene "nicked, ni-2, ni" 16-Dec-15 2015_12 "visible,recessive" wing FBgn0067343 l(3)L3D lethal (3) L3D http://flybase.net/reports/FBgn0067343.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266318 CR44983 http://flybase.net/reports/FBgn0266318.html non_protein_coding_gene CR44983 16-Dec-15 2015_12 FBgn0033179 p47 p47 http://flybase.net/reports/FBgn0033179.html FBgn0062165 protein_coding_gene "0042052=rhabdomere development, 0031468=nuclear envelope reassembly" "0005634=nucleus, 0005737=cytoplasm" "p47 a variant, anon-WO0118547.216, dp47, CG11139" "IPR029071=Ubiquitin-related domain, IPR001012=UBX domain, IPR009060=UBA-like, IPR012989=SEP domain" CG11139 16-Dec-15 2015_12 ENSDARG00000006375(nsfl1c) YBL058W(SHP1) WBGene00022381(ubxn-2) ENSXETG00000018210(ubxd4) "ENSMUSG00000027455(Nsfl1c),ENSMUSG00000028243(Ubxn2b)" "ENSG00000088833(NSFL1C),ENSG00000215114(UBXN2B)" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0265885 CR44674 http://flybase.net/reports/FBgn0265885.html non_protein_coding_gene lincRNA.613 CR44674 16-Dec-15 2015_12 FBgn0044515 l(2)Jan344 lethal (2) Jan344 http://flybase.net/reports/FBgn0044515.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030734 CG9911 http://flybase.net/reports/FBgn0030734.html FBgn0030736 protein_coding_gene 0003756=protein disulfide isomerase activity 0045454=cell redox homeostasis 0012505=endomembrane system "CG9912, LD41494p" "IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold" CG9911 16-Dec-15 2015_12 ENSDARG00000019008(erp44) WBGene00016278(C30H7.2) ENSXETG00000013069(txndc4) ENSMUSG00000028343(Erp44) ENSG00000023318(ERP44) "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0037759 CG8526 http://flybase.net/reports/FBgn0037759.html protein_coding_gene "0004622=lysophospholipase activity, 0004067=asparaginase activity" 0006520=cellular amino acid metabolic process "IPR006034=Asparaginase/glutaminase, IPR027475=Asparaginase/glutaminase, active site 2, IPR027474=L-asparaginase, N-terminal, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR027473=L-asparaginase, C-terminal domain, IPR006033=L-asparaginase, type I" CG8526 16-Dec-15 2015_12 ENSDARG00000052942(zgc:171644) WBGene00007756(C27A7.5) ENSXETG00000023076(ASPG) ENSMUSG00000037686(Aspg) ENSG00000166183(ASPG) FBgn0267621 CR45959 http://flybase.net/reports/FBgn0267621.html non_protein_coding_gene CR45959 16-Dec-15 2015_12 FBgn0065533 l(2)SH1104 lethal (2) SH1104 http://flybase.net/reports/FBgn0065533.html gene l(2)SH2 1104 16-Dec-15 2015_12 "lethal,recessive" FBgn0000924 fs(1)ne12 female sterile (1) no eggs 12 http://flybase.net/reports/FBgn0000924.html gene "ne12, fs(1)ne[12]" 16-Dec-15 2015_12 "female sterile,recessive" "endochorion,dorsal appendage,chorion" FBgn0011098 l(1)Q58 lethal (1) Q58 http://flybase.net/reports/FBgn0011098.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0027569 cert ceramide transfer protein http://flybase.net/reports/FBgn0027569.html protein_coding_gene "0035620=ceramide transporter activity, 0097001=ceramide binding, 0070273=phosphatidylinositol-4-phosphate binding" "0035621=ER to Golgi ceramide transport, 0035627=ceramide transport, 0006665=sphingolipid metabolic process" "0005794=Golgi apparatus, 0005783=endoplasmic reticulum" "Dcert, dcert, BcDNA:GH07688, CERT, CG7207" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR002913=START domain, IPR023393=START-like domain, IPR001849=Pleckstrin homology domain" CG7207 16-Dec-15 2015_12 "ENSDARG00000024325(col4a3bp),ENSDARG00000063542" WBGene00009120(F25H2.6) ENSXETG00000005085(col4a3bp) ENSMUSG00000021669(Col4a3bp) ENSG00000113163(COL4A3BP) "viable,fertile,short lived,locomotor behavior defective,heat stress response defective,stress response defective" plasma membrane FBgn0010092 Su(vg)E4 Suppressor of vestigial E4 http://flybase.net/reports/FBgn0010092.html gene vg[[EMS4]] 16-Dec-15 2015_12 FBgn0040507 ACXD ACXD http://flybase.net/reports/FBgn0040507.html FBgn0035319 protein_coding_gene 0004016=adenylate cyclase activity "0009190=cyclic nucleotide biosynthetic process, 0035556=intracellular signal transduction" 0016021=integral component of membrane "AC, CG5712, DACXD" "IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase" CG5712 16-Dec-15 2015_12 " adult stage , embryonic stage | late , larval stage | late " FBgn0259859 Su(Ste):CR42428 Su(Ste):CR42428 http://flybase.net/reports/FBgn0259859.html non_protein_coding_gene CR42428 CR42428 16-Dec-15 2015_12 FBgn0019746 l(1)83A lethal (1) 83A http://flybase.net/reports/FBgn0019746.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016723 Reg-9 Rhythmically expressed gene 9 http://flybase.net/reports/FBgn0016723.html gene "Dreg-9, Drosophila Rhythmically expressed gene 9" 16-Dec-15 2015_12 " adult stage , embryonic stage | late " adult head

FBgn0021976 l(2)k09924 lethal (2) k09924 http://flybase.net/reports/FBgn0021976.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264697 CR43966 http://flybase.net/reports/FBgn0264697.html non_protein_coding_gene CR43966 16-Dec-15 2015_12 FBgn0053536 tRNA:CR33536 transfer RNA:CR33536 http://flybase.net/reports/FBgn0053536.html FBgn0060152 tRNA_gene "0033403=UUA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002708.trna28-LeuTAA, chr3R.trna34-LeuTAA, CR33536, tRNA:L:TAA:AE002708-a" CR33536 16-Dec-15 2015_12 FBgn0001410 l(1)3Bf lethal (1) 3Bf http://flybase.net/reports/FBgn0001410.html gene "ZW-11, zw11, l[a5], zw-11, l(1)zw11" 16-Dec-15 2015_12 "lethal,recessive,maternal effect,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,female reproductive system,egg" FBgn0053742 snmRNA:430:CR33742 snmRNA:430:CR33742 http://flybase.net/reports/FBgn0053742.html non_protein_coding_gene CR33742 CR33742 16-Dec-15 2015_12 FBgn0034330 CG18107 http://flybase.net/reports/FBgn0034330.html FBgn0047044 protein_coding_gene BcDNA:RH09147 IPR013172=Immune-induced protein Dim CG18107 16-Dec-15 2015_12 viable FBgn0035041 CG13594 http://flybase.net/reports/FBgn0035041.html protein_coding_gene CG13594 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011658 meringue meringue http://flybase.net/reports/FBgn0011658.html gene "0048477=oogenesis, 0007296=vitellogenesis" 16-Dec-15 2015_12 FBgn0040941 CG15308 http://flybase.net/reports/FBgn0040941.html protein_coding_gene CG15308 16-Dec-15 2015_12 "viable,fertile" FBgn0259559 GG01082 http://flybase.net/reports/FBgn0259559.html gene 16-Dec-15 2015_12 visible "mediproboscis,wing" FBgn0003735 tov tiny ovaries http://flybase.net/reports/FBgn0003735.html gene 16-Dec-15 2015_12 female sterile ovary FBgn0036363 CG10140 http://flybase.net/reports/FBgn0036363.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG10140 16-Dec-15 2015_12 viable FBgn0024617 ms59I-26A ms59I-26A http://flybase.net/reports/FBgn0024617.html gene 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective,cytokinesis defective" FBgn0037937 Fer3 48 related 3 http://flybase.net/reports/FBgn0037937.html FBgn0062470 protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0045892=negative regulation of transcription, DNA-templated, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "ntwist, N-twist, nato3, nephew of atonal 3, BcDNA:LD04689, bHLHa32, Dnato3, CG6913" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG6913 16-Dec-15 2015_12 "ENSDARG00000030347(mespb),ENSDARG00000017078(mespa)" ENSMUSG00000073043(Atoh1) "ENSG00000176009(ASCL3),ENSG00000205899(BHLHA9)" " embryonic stage | stage 11-16 , embryonic stage | stage 13-16 " " ventral nerve cord primordium | segmentally repeated & restricted

, embryonic procephalic segment | restricted

" FBgn0060409 l(3)S130509 lethal (3) S130509 http://flybase.net/reports/FBgn0060409.html gene 1305/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000807 Fs(2)G Female sterile of Grell http://flybase.net/reports/FBgn0000807.html gene Fs(2)D 16-Dec-15 2015_12 "female sterile,dominant,male fertile,viable,reduced,heat sensitive,visible" "egg chamber,ovary,oviduct,oocyte,macrochaeta,wing,heat sensitive,adult thorax" FBgn0263208 CR43378 http://flybase.net/reports/FBgn0263208.html pseudogene_attribute CR43378 16-Dec-15 2015_12 FBgn0063549 Dm88\rt rt http://flybase.net/reports/FBgn0063549.html transposable_element_gene "IPR013103=Reverse transcriptase, RNA-dependent DNA polymerase" 16-Dec-15 2015_12 FBgn0023106 anon-13Fb anon-13Fb http://flybase.net/reports/FBgn0023106.html gene 16-Dec-15 2015_12 FBgn0020584 anon-59Ca anon-59Ca http://flybase.net/reports/FBgn0020584.html gene 16-Dec-15 2015_12 FBgn0259942 Ttd7 TRPL translocation defect 7 http://flybase.net/reports/FBgn0259942.html protein_coding_gene TRPL translocation defect 7 16-Dec-15 2015_12 FBgn0261545 CG42663 http://flybase.net/reports/FBgn0261545.html "FBgn0033772, FBgn0033771, FBgn0062877, FBgn0040756" protein_coding_gene 0008340=determination of adult lifespan "CG13486, CG18356, CG12488, BcDNA:SD15892" IPR026163=Nck-associated protein 5-like CG42663 16-Dec-15 2015_12 ENSXETG00000009780(KIAA1602) """DRSC06158, DRSC06404"" " IEK FBgn0082191 l(3)Me10 lethal (3) Me10 http://flybase.net/reports/FBgn0082191.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone,decreased cell size,decreased cell number,size defective,cell autonomous,cell non-autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage" "chaeta,somatic clone,wing,adult abdomen,mesothoracic tergum,wing hair,microchaeta,macrochaeta" FBgn0010428 anon-61C anon-61C http://flybase.net/reports/FBgn0010428.html FBgn0010430 repeat_region 16-Dec-15 2015_12 FBgn0038545 CG7713 http://flybase.net/reports/FBgn0038545.html protein_coding_gene dmCG7713 CG7713 16-Dec-15 2015_12 lethal FBgn0040732 CG16926 http://flybase.net/reports/FBgn0040732.html protein_coding_gene 141315_at CG16926 16-Dec-15 2015_12 viable FBgn0001557 l(1)19Cb lethal (1) 19Cb http://flybase.net/reports/FBgn0001557.html gene 16-398 16-Dec-15 2015_12 "lethal,recessive" FBgn0014923 anon-72ABg anon-72ABg http://flybase.net/reports/FBgn0014923.html gene 16-Dec-15 2015_12 FBgn0004231 l(3)93Be lethal (3) 93Be http://flybase.net/reports/FBgn0004231.html gene rlr3 16-Dec-15 2015_12 lethal FBgn0038458 VhaM9.7-d Vacuolar H+ ATPase M9.7 subunit d http://flybase.net/reports/FBgn0038458.html protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033179=proton-transporting V-type ATPase, V0 domain, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "CG14909, vhaM9.7-4, Vacuolar H[+] ATPase subunit M9.7-d" "IPR017385=ATPase, V0 complex, subunit e1/e2, metazoa, IPR008389=ATPase, V0 complex, subunit e1/e2" CG14909 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0002361 l(3)87Ei lethal (3) 87Ei http://flybase.net/reports/FBgn0002361.html gene "l(3)s9, l(3)S9, S9, l(3)m102" 16-Dec-15 2015_12 lethal FBgn0264568 CR43940 http://flybase.net/reports/FBgn0264568.html non_protein_coding_gene CR43940 16-Dec-15 2015_12 FBgn0002015 l(2)36Fh lethal (2) 36Fh http://flybase.net/reports/FBgn0002015.html gene l(2)E50 16-Dec-15 2015_12 lethal FBgn0083307 E(smoDN)1485 Enhancer of smoDN 1485 http://flybase.net/reports/FBgn0083307.html gene 16-Dec-15 2015_12 FBgn0003197 rag ragged http://flybase.net/reports/FBgn0003197.html gene 16-Dec-15 2015_12 wing margin FBgn0016863 l(2)39ADa lethal (2) 39ADa http://flybase.net/reports/FBgn0016863.html gene B819 16-Dec-15 2015_12 lethal FBgn0040730 CG15127 http://flybase.net/reports/FBgn0040730.html FBgn0034466 protein_coding_gene CG18365 CG15127 16-Dec-15 2015_12 viable FBgn0259264 EP-689 http://flybase.net/reports/FBgn0259264.html gene 16-Dec-15 2015_12 visible wing hair FBgn0260368 GSd203 http://flybase.net/reports/FBgn0260368.html gene 16-Dec-15 2015_12 lethal FBgn0001678 l(1)EN16 lethal (1) from Eugene Nonautonomous 16 http://flybase.net/reports/FBgn0001678.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260322 GSd457 http://flybase.net/reports/FBgn0260322.html gene 16-Dec-15 2015_12 lethal FBgn0053375 5SrRNA:CR33375 5SrRNA:CR33375 http://flybase.net/reports/FBgn0053375.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33375 CR33375 16-Dec-15 2015_12 FBgn0002014 l(2)36Fg lethal (2) 36Fg http://flybase.net/reports/FBgn0002014.html gene l(2)E20 16-Dec-15 2015_12 lethal FBgn0002097 l(2)57Cc lethal (2) 57Cc http://flybase.net/reports/FBgn0002097.html gene 16-Dec-15 2015_12 lethal FBgn0260592 2L2475 http://flybase.net/reports/FBgn0260592.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0044018 SY2-2 SY2-2 http://flybase.net/reports/FBgn0044018.html gene 16-Dec-15 2015_12 FBgn0038404 CG8925 http://flybase.net/reports/FBgn0038404.html protein_coding_gene 0015226=carnitine transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily, IPR005829=Sugar transporter, conserved site" CG8925 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0028232 l(3)S003704 lethal (3) S003704 http://flybase.net/reports/FBgn0028232.html gene 0037/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0040895 CG14773 http://flybase.net/reports/FBgn0040895.html protein_coding_gene 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17950 IE 0.733114108 1.531585814 8.741944617 -1.333350713 -1.299148299 -0.447122001 FBgn0016079 xerox xerox http://flybase.net/reports/FBgn0016079.html repeat_region 16-Dec-15 2015_12 FBgn0262066 SG46 http://flybase.net/reports/FBgn0262066.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0015761 Mei66F Meiotic 66F-67A http://flybase.net/reports/FBgn0015761.html gene 16-Dec-15 2015_12 FBgn0027168 l(2)IH1 lethal (2) IH1 http://flybase.net/reports/FBgn0027168.html gene unnamed 16-Dec-15 2015_12 lethal FBgn0011091 l(1)Q51 lethal (1) Q51 http://flybase.net/reports/FBgn0011091.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0267167 CR45607 http://flybase.net/reports/FBgn0267167.html non_protein_coding_gene CR45607 16-Dec-15 2015_12 FBgn0043865 SA-2 Stromalin-2 http://flybase.net/reports/FBgn0043865.html "FBgn0035220, FBgn0043933" protein_coding_gene "0005730=nucleolus, 0000794=condensed nuclear chromosome, 0005634=nucleus" "pairing failure-1, SNM, snm, CG1, stromalin in meiosis, anon-WO0109301.35, Complementation group 1, CG13916, pf-1" "IPR016024=Armadillo-type fold, IPR020839=Stromalin conservative domain, IPR013721=STAG" CG13916 16-Dec-15 2015_12 YIL026C(IRR1) meiotic cell cycle defective "meiosis I & nuclear chromosome,G2 phase & nuclear chromosome" FBgn0069213 hoernchen hoernchen http://flybase.net/reports/FBgn0069213.html gene "0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded" hrn 16-Dec-15 2015_12 "viable,female sterile,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect" FBgn0016896 l(3)64Cf lethal (3) 64Cf http://flybase.net/reports/FBgn0016896.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265623 Su(z)2 Suppressor of zeste 2 http://flybase.net/reports/FBgn0265623.html "FBgn0008654, FBgn0000118, FBgn0022134, FBgn0003645" protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0006342=chromatin silencing "0005725=intercalary heterochromatin, 0035102=PRC1 complex, 0005634=nucleus" "Suppressor of zeste 3, Arp, Aristapedioid, Suppressor of zeste (2), Aristopedoid, Su(Z)2, Suppressor 2 of zeste, CG3905, SU(Z)2, su(z)3, SUZ2, Supressor of zeste 2, l(2)k06344, Suz2, su(z)2, Suppressor of Zeste 3, Suppressor of zeste two, Su(z)3, Su(z)[[2]], Suppressor of zeste (3), Su(z)2D" "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR018957=Zinc finger, C3HC4 RING-type" CG3905 16-Dec-15 2015_12 FBgn0264545 CG43924 http://flybase.net/reports/FBgn0264545.html protein_coding_gene CG43924 16-Dec-15 2015_12 FBgn0085648 CG41429 http://flybase.net/reports/FBgn0085648.html FBan0041429 protein_coding_gene 16-Dec-15 2015_12 FBgn0028033 l(3)S101902 lethal (3) S101902 http://flybase.net/reports/FBgn0028033.html gene 1019/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0060797 l(3)S057806 lethal (3) S057806 http://flybase.net/reports/FBgn0060797.html gene 0578/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0011980 tRNA:S774:12Ec transfer RNA:ser774:12Ec http://flybase.net/reports/FBgn0011980.html "FBgn0003830, FBgn0011968, FBgn0052612, FBgn0060067" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033405=UCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "unnamed, 774-1, transfer RNA:ser, AE002593.trna15-SerAGA, tRNA[[Ser]], tRNA:ser774:12Ec, CR32612, tRNA:S:AGA:AE002593-e, chrX.trna24-SerAGA, tRNA:ser, tRNA:S, Ser-tRNA-4-7" CR32612 16-Dec-15 2015_12 FBgn0264338 CR43794 http://flybase.net/reports/FBgn0264338.html non_protein_coding_gene lincRNA.386 CR43794 16-Dec-15 2015_12 FBgn0031018 CG12200 http://flybase.net/reports/FBgn0031018.html protein_coding_gene 0008270=zinc ion binding "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site" CG12200 16-Dec-15 2015_12 "WBGene00008387(D1081.9),WBGene00018867(F55A12.10)" ENSMUSG00000071425(Gm10332) ENSG00000215277(LOC100507650) viable FBgn0062679 EP2086 EP2086 http://flybase.net/reports/FBgn0062679.html gene EP(2)2086 16-Dec-15 2015_12 FBgn0028179 l(3)S024639b lethal (3) S024639b http://flybase.net/reports/FBgn0028179.html gene "0246/39, l(3)S024639" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0050295 Ipk1 Ipk1 http://flybase.net/reports/FBgn0050295.html "FBgn0034555, FBgn0034556, FBgn0034557" protein_coding_gene "0005524=ATP binding, 0035299=inositol pentakisphosphate 2-kinase activity" 0032958=inositol phosphate biosynthetic process "CG15229, CG15228, CG15230, dmIpk1, CG30295" IPR009286=Inositol-pentakisphosphate 2-kinase CG30295 16-Dec-15 2015_12 ENSDARG00000003446(ippk) WBGene00012466(Y17G7B.13) ENSXETG00000020924(IPPK) ENSMUSG00000021385(Ippk) ENSG00000127080(IPPK) "partially lethal - majority die,some die during pupal stage" FBgn0035511 Cpr64Ab Cuticular protein 64Ab http://flybase.net/reports/FBgn0035511.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG15007, DmelCpr64Ab" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG15007 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0035988 CG3982 http://flybase.net/reports/FBgn0035988.html protein_coding_gene bs12d10.y1 CG3982 16-Dec-15 2015_12 lethal FBgn0050238 tRNA:CR30238 transfer RNA:CR30238 http://flybase.net/reports/FBgn0050238.html FBgn0011847 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "transfer RNA:glu4:53A, tRNA:glu4:53A, chr2R.trna72-GluTTC, tRNA:E4:53A, tRNA:Glu, CR30238" CR30238 16-Dec-15 2015_12 FBgn0005386 ash1 "absent, small, or homeotic discs 1" http://flybase.net/reports/FBgn0005386.html "FBgn0000138, FBgn0004672, FBgn0005228" protein_coding_gene "0042800=histone methyltransferase activity (H3-K4 specific), 0003682=chromatin binding, 0003677=DNA binding, 0046974=histone methyltransferase activity (H3-K9 specific), 0018024=histone-lysine N-methyltransferase activity, 0008270=zinc ion binding, 0042054=histone methyltransferase activity, 0042799=histone methyltransferase activity (H4-K20 specific), 0035035=histone acetyltransferase binding" "0048096=chromatin-mediated maintenance of transcription, 0048477=oogenesis, 0018991=oviposition, 0006355=regulation of transcription, DNA-templated, 0016571=histone methylation, 0051568=histone H3-K4 methylation, 0001700=embryonic development via the syncytial blastoderm" "0000785=chromatin, 0005700=polytene chromosome, 0043234=protein complex, 0005634=nucleus" "discs absent, small, or homeotic-1, ash, l(3)76BDb, ASH1, CG8887, Ash 1, dash, Ash1, ash-1, Absent, small or homeotic discs 1, absent, small or homeotic discs 1, l(3)SG29a, absent small or homeotic 1, discs absent, small, or homeotic, Absent, small, or homeotic disc 1, Ash" "IPR017956=AT hook, DNA-binding motif, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR001214=SET domain, IPR001025=Bromo adjacent homology (BAH) domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR006560=AWS domain, IPR001965=Zinc finger, PHD-type, IPR003616=Post-SET domain" CG8887 16-Dec-15 2015_12 WBGene00003040(lin-59) " adult stage && oogenesis stage , embryonic stage | early , embryonic stage -- adult stage , larval stage | third instar " " nurse cell

, imaginal disc

" "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,lethal,short lived,lethal - all die before end of P-stage,some die during pharate adult stage,visible,homeotic,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,non-suppressor of variegation,non-enhancer of variegation,suppressor of variegation,dominant,female limited,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,viable" "abdominal segment 2,abdominal segment 7,male,ovary,heat sensitive,wing,haltere,ectopic,imaginal disc,heart primordium,abdominal segment,metathoracic segment,abdominal segment 6,haltere disc" FBgn0267720 CR46053 http://flybase.net/reports/FBgn0267720.html non_protein_coding_gene CR46053 16-Dec-15 2015_12 FBgn0040093 lectin-46Ca lectin-46Ca http://flybase.net/reports/FBgn0040093.html FBgn0033445 protein_coding_gene "0030246=carbohydrate binding, 0005534=galactose binding" "0032504=multicellular organism reproduction, 0046008=regulation of female receptivity, post-mating, 0046692=sperm competition, 0008104=protein localization" "0005615=extracellular space, 0009986=cell surface" "CG1656, Lectin-46Ca, Lectin-46CA, AC007330a, AC 007330A, lectin-44Ca" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG1656 16-Dec-15 2015_12 "mating rhythm defective,viable" FBgn0264546 CG43925 http://flybase.net/reports/FBgn0264546.html protein_coding_gene CG43925 16-Dec-15 2015_12 FBgn0086404 BG02745 http://flybase.net/reports/FBgn0086404.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0003990 vs vesiculated http://flybase.net/reports/FBgn0003990.html gene bw 16-Dec-15 2015_12 "visible,viable,fertile,partially lethal - majority live,reduced,male,female" wing FBgn0033993 CG8089 http://flybase.net/reports/FBgn0033993.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR003604=Zinc finger, U1-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG8089 16-Dec-15 2015_12 "viable,fertile" FBgn0011719 Su(top) Suppressor of torpedo http://flybase.net/reports/FBgn0011719.html gene 16-Dec-15 2015_12 FBgn0050089 CG30089 http://flybase.net/reports/FBgn0050089.html "FBgn0034040, FBgn0034041, FBgn0040745" protein_coding_gene "CG12966, CG12305, CG12967" CG30089 16-Dec-15 2015_12 "neuroanatomy defective,viable" "ectoderm derivative,neuron,longitudinal connective,ventral nerve cord" DRSC06267 E 0.222556357 0.631911206 7.425979346 0.506528203 0.00366233 -0.69295859 FBgn0012035 Akr Aldo-keto reductase http://flybase.net/reports/FBgn0012035.html gene 0004033=aldo-keto reductase (NADP) activity 16-Dec-15 2015_12 FBgn0052024 CG32024 http://flybase.net/reports/FBgn0052024.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG32024 16-Dec-15 2015_12 FBgn0022236 l(2)k02520 lethal (2) k02520 http://flybase.net/reports/FBgn0022236.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037461 CG15177 http://flybase.net/reports/FBgn0037461.html protein_coding_gene 0005509=calcium ion binding "IPR028846=Recoverin family, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG15177 16-Dec-15 2015_12 "viable,fertile" FBgn0050232 tRNA:CR30232 transfer RNA:CR30232 http://flybase.net/reports/FBgn0050232.html FBgn0060274 tRNA_gene 0033455=GCA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002787.trna12-AlaTGC, tRNA[[Ala]], chr2R.trna70-AlaTGC, tRNA:A:TGC:AE002787-a, CR30232" CR30232 16-Dec-15 2015_12 FBgn0010228 HmgZ HMG protein Z http://flybase.net/reports/FBgn0010228.html FBgn0063041 protein_coding_gene 0003677=DNA binding 0005634=nucleus "HMG-Z, hmgz, BcDNA:RE28596, HMG1, HMG Z, CG17921, hmg-Z, dHMG-Z, clone 1.58, anon-EST:Liang-1.58" IPR009071=High mobility group box domain CG17921 16-Dec-15 2015_12 "YMR072W(ABF2),YPR052C(NHP6A),YBR089C-A(NHP6B)" WBGene00001971(hmg-1.1) " embryonic stage , larval stage | first instar " viable rhabdomere R7 DRSC03888 E -0.382273936 1.177141099 2.270112586 0.403115766 0.231879163 0.515644364 FBgn0002865 Mst98Ca Male-specific RNA 98Ca http://flybase.net/reports/FBgn0002865.html protein_coding_gene 0007286=spermatid development 0036126=sperm flagellum "mst(3)gl-12, MST98Ca, Mst, mst336, CG11719, Mst98C, Mst98CE" CG11719 16-Dec-15 2015_12 viable DRSC16749 K 0.701349684 -0.173249827 0.24635948 0.425580395 -2.226765935 0.470420068 FBgn0015570 ë±-Est2 ë±-Esterase-2 http://flybase.net/reports/FBgn0015570.html protein_coding_gene 0052689=carboxylic ester hydrolase activity 0005811=lipid particle "B, alpha-Esterase-2, aE2, Alpha-Est2, unnamed, alphaE2, alpha-EST2, DmalphaE2, alpha-esterase 2, fragment B, alpha-Est2, CG2505" "IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG2505 16-Dec-15 2015_12 "WBGene00020891(T28C12.4),WBGene00020892(T28C12.5)" viable FBgn0065952 l(2)SH0069 lethal (2) SH0069 http://flybase.net/reports/FBgn0065952.html gene l(2)SH2 0069 16-Dec-15 2015_12 "lethal,recessive" FBgn0002810 ms(1)516 male sterile (1) 516 http://flybase.net/reports/FBgn0002810.html gene 16-Dec-15 2015_12 "male sterile,recessive,meiotic cell cycle defective,male" "meiosis II & spindle | male,spermatid & nucleus,meiosis II & chromosome, pericentric region,Nebenkern,meiotic cell cycle & centriole | male,meiosis II & aster | male,meiosis II & nuclear chromosome | male,spermatid" FBgn0061044 l(3)S023639 lethal (3) S023639 http://flybase.net/reports/FBgn0061044.html gene 0236/39 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052712 CG32712 http://flybase.net/reports/FBgn0052712.html protein_coding_gene CG32712 16-Dec-15 2015_12 FBgn0266994 CR45445 http://flybase.net/reports/FBgn0266994.html non_protein_coding_gene CR45445 16-Dec-15 2015_12 FBgn0046697 Ppr-Y Ppr-Y http://flybase.net/reports/FBgn0046697.html "FBgn0058440, FBan0040440" protein_coding_gene 0008599=protein phosphatase type 1 regulator activity 0006470=protein dephosphorylation "PprY, CG40440, PPr-Y" IPR001611=Leucine-rich repeat CG40440 16-Dec-15 2015_12 ENSDARG00000041300(lrrc48) WBGene00019842(R02F11.4) ENSXETG00000012155(LRRC48) ENSMUSG00000056598(Lrrc48) ENSG00000171962(LRRC48) FBgn0039928 Cals Calsyntenin-1 http://flybase.net/reports/FBgn0039928.html protein_coding_gene 0005509=calcium ion binding "0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0044331=cell-cell adhesion mediated by cadherin, 0007268=synaptic transmission, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" "0005887=integral component of plasma membrane, 0005576=extracellular region, 0045211=postsynaptic membrane" "CG11059, Cals, cals, DCad102F, Calsyntenin-1, CALS, calsyntenin-1, CT30877, calsyntenin-1-like, Cad102F" "IPR015919=Cadherin-like, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR026914=Calsyntenin, IPR002126=Cadherin" CG11059 16-Dec-15 2015_12 "ENSDARG00000031720(clstn1),ENSDARG00000060637(clstn2),ENSDARG00000060638(LOC569664),ENSDARG00000038734" WBGene00000403(casy-1) "ENSXETG00000020738(CLSTN2),ENSXETG00000023916(CLSTN3)" "ENSMUSG00000032452(Clstn2),ENSMUSG00000039953(Clstn1),ENSMUSG00000008153(Clstn3)" "ENSG00000158258(CLSTN2),ENSG00000171603(CLSTN1),ENSG00000139182(CLSTN3)" "viable,fertile" FBgn0067403 Rst(2)DDT-EMS1 Resistant to DDT on II EMS1 http://flybase.net/reports/FBgn0067403.html gene Rst(2)DDT 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0265984 CR44763 http://flybase.net/reports/FBgn0265984.html non_protein_coding_gene lincRNA.377 CR44763 16-Dec-15 2015_12 FBgn0030341 p24-1 p24-related-1 http://flybase.net/reports/FBgn0030341.html FBgn0025988 protein_coding_gene 0005215=transporter activity "0006892=post-Golgi vesicle-mediated transport, 0061357=positive regulation of Wnt protein secretion, 0048193=Golgi vesicle transport, 0000003=reproduction, 0022008=neurogenesis, 0048042=regulation of post-mating oviposition" "0030135=coated vesicle, 0030133=transport vesicle, 0016021=integral component of membrane" "anon-EST:Liang-1.45, clone 1.45, p24.1, p26/p24gamma4, p24, CG1967" "IPR015720=TMP21-related, IPR009038=GOLD domain" CG1967 16-Dec-15 2015_12 "ENSDARG00000046022(tmed7),ENSDARG00000028816(tmed3)" WBGene00019003(F57B10.5) ENSXETG00000018742(tmed7) "ENSMUSG00000032353(Tmed3),ENSMUSG00000033184" ENSG00000166557(TMED3) "viable,fertile,lethal,neuroanatomy defective,female semi-sterile,male sterile,male semi-sterile" "embryonic/larval neuroblast,ganglion mother cell,wing margin" FBgn0267090 CR45534 http://flybase.net/reports/FBgn0267090.html non_protein_coding_gene CR45534 16-Dec-15 2015_12 FBgn0085562 CG41232 http://flybase.net/reports/FBgn0085562.html FBan0041232 protein_coding_gene 16-Dec-15 2015_12 FBgn0005090 fs(2)OWc2 female sterile (2) OWc2 http://flybase.net/reports/FBgn0005090.html gene 16-Dec-15 2015_12 FBgn0266594 CR45119 http://flybase.net/reports/FBgn0266594.html non_protein_coding_gene CR45119 16-Dec-15 2015_12 FBgn0051860 ZnT33D Zinc transporter 33D http://flybase.net/reports/FBgn0051860.html FBgn0032418 protein_coding_gene 0005385=zinc ion transmembrane transporter activity "0006829=zinc II ion transport, 0006882=cellular zinc ion homeostasis, 0055085=transmembrane transport" "0005622=intracellular, 0016021=integral component of membrane, 0016323=basolateral plasma membrane" "cg31860, CG17215, CG31860, dZnT33D" "IPR002524=Cation efflux protein, IPR027469=Cation efflux protein transmembrane domain" CG31860 16-Dec-15 2015_12 "ENSDARG00000021305(slc30a2),ENSDARG00000057629" WBGene00011821(cdf-2) ENSXETG00000009196(Q6DF59_XENTR) ENSMUSG00000022315(Slc30a8) "lethal,visible,some die during pupal stage,body color defective,lethal - all die during larval stage" "eye,adult thorax,humeral bristle" FBgn0065704 l(2)SH0618 lethal (2) SH0618 http://flybase.net/reports/FBgn0065704.html gene l(2)SH2 0618 16-Dec-15 2015_12 "lethal,recessive" FBgn0041771 anon-d29 anon-d29 http://flybase.net/reports/FBgn0041771.html gene d29 16-Dec-15 2015_12 FBgn0032638 SPH93 http://flybase.net/reports/FBgn0032638.html protein_coding_gene 0004252=serine-type endopeptidase activity "0050830=defense response to Gram-positive bacterium, 0006508=proteolysis" "SPH93, CG6639, c-SPH93" "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG6639 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" "lethal,viable" FBgn0023080 h::Kr h::Kr http://flybase.net/reports/FBgn0023080.html engineered_fusion_gene 16-Dec-15 2015_12 "viable,partially" "abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8" FBgn0024263 acd(2)5M38 auditory courtship defective 5M38 http://flybase.net/reports/FBgn0024263.html gene "0031223=auditory behavior, 0008049=male courtship behavior" unnamed 16-Dec-15 2015_12 "viable,auditory perception defective" FBgn0005354 su(faswb) suppressor of facet-strawberry http://flybase.net/reports/FBgn0005354.html gene 16-Dec-15 2015_12 FBgn0029693 CG6379 http://flybase.net/reports/FBgn0029693.html protein_coding_gene "0003676=nucleic acid binding, 0004483=mRNA (nucleoside-2'-O-)-methyltransferase activity" "0080009=mRNA methylation, 0006370=7-methylguanosine mRNA capping, 0097309=cap1 mRNA methylation" 0005634=nucleus "IPR000467=G-patch domain, IPR030376=Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1, IPR002877=Ribosomal RNA methyltransferase FtsJ domain, IPR025816=RrmJ-type ribose 2-O-methyltransferase domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG6379 16-Dec-15 2015_12 ENSDARG00000030830(ftsjd2) WBGene00013160(Y53F4B.13) ENSXETG00000009964(FTSJD2) ENSMUSG00000024019(Ftsjd2) ENSG00000137200(FTSJD2) "viable,fertile" FBgn0265169 CR44238 http://flybase.net/reports/FBgn0265169.html non_protein_coding_gene CR44238 16-Dec-15 2015_12 FBgn0069179 mcl(2)Z2641 mcl(2)Z2641 http://flybase.net/reports/FBgn0069179.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0250834 CG33308 http://flybase.net/reports/FBgn0250834.html "FBgn0082664, FBgn0053308, FBgn0086609, FBgn0066956" protein_coding_gene "BP1076, HDC02577, CG33308, unnamed, anon-SAGE:Wang-042" CG33308 16-Dec-15 2015_12 DRSC01419 IE 0.165505781 -1.779915254 -1.763961375 -1.239442783 0.615520235 -0.825164962 FBgn0259224 CG42324 http://flybase.net/reports/FBgn0259224.html "FBgn0035450, FBgn0035451" protein_coding_gene "CG14972, CG14973" CG42324 16-Dec-15 2015_12 FBgn0011066 l(1)Q19 lethal (1) Q19 http://flybase.net/reports/FBgn0011066.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0014224 l(2)31Ec lethal (2) 31Ec http://flybase.net/reports/FBgn0014224.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085817 CR41607 http://flybase.net/reports/FBgn0085817.html FBan0041607 rRNA_gene CR41607 16-Dec-15 2015_12 FBgn0011449 l(3)neo5 lethal (3) neo5 http://flybase.net/reports/FBgn0011449.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035817 CG7409 http://flybase.net/reports/FBgn0035817.html protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding CT16169 "IPR031107=Small heat shock protein HSP20, IPR008978=HSP20-like chaperone, IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain" CG7409 16-Dec-15 2015_12 WBGene00002021(hsp-17) viable DRSC10842 K 0.697776589 0.820126421 -0.181723297 0.842768195 0.565623854 1.514161403 FBgn0033108 CG15236 http://flybase.net/reports/FBgn0033108.html protein_coding_gene CG15236 16-Dec-15 2015_12 "viable,fertile" FBgn0034403 CG18190 http://flybase.net/reports/FBgn0034403.html protein_coding_gene 0008017=microtubule binding 0005875=microtubule associated complex "IPR001715=Calponin homology domain, IPR004953=EB1, C-terminal, IPR027328=Microtubule-associated protein RP/EB" CG18190 16-Dec-15 2015_12 FBgn0039911 CG1909 http://flybase.net/reports/FBgn0039911.html protein_coding_gene "0033130=acetylcholine receptor binding, 0043495=protein anchor, 0008270=zinc ion binding" "0007271=synaptic transmission, cholinergic" 0005886=plasma membrane "IPR001841=Zinc finger, RING-type, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019568=Rapsyn, myristoylation/linker region, N-terminal, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG1909 16-Dec-15 2015_12 ENSDARG00000041133(rapsn) WBGene00004507(rpy-1) ENSXETG00000009048(rapsn) ENSMUSG00000002104(Rapsn) ENSG00000165917(RAPSN) viable FBgn0030628 CG9114 http://flybase.net/reports/FBgn0030628.html protein_coding_gene CG9114 16-Dec-15 2015_12 "viable,fertile" DRSC20155 K 0.027022366 1.355397897 -0.251801936 -0.017977546 -1.70615625 -0.539850059 FBgn0265598 Bx Beadex http://flybase.net/reports/FBgn0265598.html "FBgn0001183, FBgn0000242, FBgn0004958, FBgn0015251, FBgn0030935" protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding" "0036011=imaginal disc-derived leg segmentation, 0035218=leg disc development, 0007476=imaginal disc-derived wing morphogenesis, 0022414=reproductive process, 0002121=inter-male aggressive behavior, 0035483=gastric emptying, 0022416=chaeta development, 0042220=response to cocaine, 0045475=locomotor rhythm, 0006909=phagocytosis, 0045893=positive regulation of transcription, DNA-templated" 0005634=nucleus "fliH, DLMO, hdp-a, hdp, rhombotin, Rhombotin, Bd, CG6500, Dlmo, dttg, dLmo, hld, Pointedoid, LIM-only, Ptd, CG15048, Rho, beadex/dLMO, heldup a, dLMO, CG10548, flightless-H, CG44425, Lmo, beadex, LMO, held-up, dlmo" "IPR001781=Zinc finger, LIM-type" CG44425 16-Dec-15 2015_12 FBgn0085738 CR40503 http://flybase.net/reports/FBgn0085738.html FBan0040503 rRNA_gene 16-Dec-15 2015_12 FBgn0038213 CG9624 http://flybase.net/reports/FBgn0038213.html protein_coding_gene CG9624 16-Dec-15 2015_12 viable FBgn0024711 anon-63Ea anon-63Ea http://flybase.net/reports/FBgn0024711.html gene Gene 17 16-Dec-15 2015_12 FBgn0038719 CG16727 http://flybase.net/reports/FBgn0038719.html protein_coding_gene 0015101=organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG16727 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0039787 CG9702 http://flybase.net/reports/FBgn0039787.html protein_coding_gene "0005215=transporter activity, 0015381=high-affinity sulfate transmembrane transporter activity" "0055085=transmembrane transport, 0008272=sulfate transport" 0016021=integral component of membrane "IPR002645=STAS domain, IPR001902=SLC26A/SulP transporter, IPR011547=SLC26A/SulP transporter domain" CG9702 16-Dec-15 2015_12 "YLR092W(SUL2),YBR294W(SUL1)" ENSXETG00000019624(SLC26A11) "partially lethal - majority die,some die during pupal stage" FBgn0001637 l(1)dn17 lethal (1) discs normal 17 http://flybase.net/reports/FBgn0001637.html gene l(1)d.norm.-17 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016731 SR3-10 Suppressor of Ras85D 3-10 http://flybase.net/reports/FBgn0016731.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052274 Drsl1 Drosomycin-like 1 http://flybase.net/reports/FBgn0052274.html FBgn0035441 protein_coding_gene "0006952=defense response, 0050832=defense response to fungus" 0005576=extracellular region "Dro-H, Drs-like, Drs-l, Drs-I, Dro1, dro1b, Dro-1, Drs-lC, drosomycin-1b, Drosomycin-like C, drosomycin, drosomycin-H, Drosomycin-1, Drosomycin-like, CG11520, drosomycin-1, CG32274" "IPR003614=Knottin, scorpion toxin-like" CG32274 16-Dec-15 2015_12 viable FBgn0263488 CR43603 http://flybase.net/reports/FBgn0263488.html non_protein_coding_gene unsRNA:CG10576-a CR43603 16-Dec-15 2015_12 FBgn0038280 CG14861 http://flybase.net/reports/FBgn0038280.html protein_coding_gene 0005509=calcium ion binding "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG14861 16-Dec-15 2015_12 WBGene00012980(Y48B6A.6) viable FBgn0263474 scaRNA:ë¬U2-38.40.42 small Cajal body-specific RNA : ë¬U2-38.40.42 http://flybase.net/reports/FBgn0263474.html snoRNA_gene 0030565=snRNA pseudouridylation guide activity 0015030=Cajal body "pugU2-38/40/42, snoRNA:bur-a" CR43589 16-Dec-15 2015_12 FBgn0033829 CG17062 http://flybase.net/reports/FBgn0033829.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034072 Dg Dystroglycan http://flybase.net/reports/FBgn0034072.html protein_coding_gene "0008307=structural constituent of muscle, 0005509=calcium ion binding, 0005515=protein binding" "0016334=establishment or maintenance of polarity of follicular epithelium, 0045214=sarcomere organization, 0007309=oocyte axis specification, 0031532=actin cytoskeleton reorganization, 0007314=oocyte anterior/posterior axis specification, 0006110=regulation of glycolytic process, 0007295=growth of a germarium-derived egg chamber, 0060025=regulation of synaptic activity, 0007016=cytoskeletal anchoring at plasma membrane, 1903798=regulation of production of miRNAs involved in gene silencing by miRNA, 0007163=establishment or maintenance of cell polarity, 0007411=axon guidance, 0035088=establishment or maintenance of apical/basal cell polarity, 0007474=imaginal disc-derived wing vein specification, 0030010=establishment of cell polarity, 0046716=muscle cell cellular homeostasis, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0007293=germarium-derived egg chamber formation, 0016203=muscle attachment" "0005886=plasma membrane, 0009925=basal plasma membrane, 0030018=Z disc, 0042383=sarcolemma, 0031594=neuromuscular junction, 0016010=dystrophin-associated glycoprotein complex, 0016011=dystroglycan complex, 0030315=T-tubule" "DmDG, DG, alphaDystroglycan, Dystroglican, dystroglycan, CG18250, CT41273, atsugari, dys, dg, atu, dystroglycan-like, dgn" "IPR015919=Cadherin-like, IPR006644=Dystroglycan-type cadherin-like, IPR027468=Alpha-dystroglycan domain 2, IPR030398=DG-type SEA domain, IPR008465=Dystroglycan, IPR013783=Immunoglobulin-like fold" CG18250 16-Dec-15 2015_12 ENSMUSG00000039952(Dag1) "behavior defective,thermotaxis behavior defective,cell polarity defective,neurophysiology defective,visible,partially lethal - majority live,viable,lethal - all die before end of larval stage,some die during third instar larval stage,germline clone,neuroanatomy defective,somatic clone,cell autonomous,cell non-autonomous,locomotor behavior defective,conditional,partially lethal - majority die,some die during larval stage" "oocyte,embryonic/larval neuromuscular junction,crossvein,stress fiber,follicle cell,egg,maternal effect,stress fiber | cell autonomous | somatic clone,cell autonomous,somatic clone,hemocyte,leg,wing,eye,stage S6 oocyte,germline clone,embryonic/larval muscle system,muscle attachment site,sarcomere | second instar larval stage,posterior crossvein,ring canal,eye photoreceptor cell,lamina plexus,eye disc,cell non-autonomous,glial cell,oocyte associated follicle cell,embryonic/larval muscle system | third instar larval stage,sarcomere | third instar larval stagetub.PU,indirect flight muscle,conditional,lamina plexus | third instar larval stage,eye disc | third instar larval stage,eye photoreceptor cell | third instar larval stage,sarcomere | third instar larval stagehow-24B" FBgn0041752 hexe hexe http://flybase.net/reports/FBgn0041752.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,recessive,lethal,hyperplasia,chemical resistant,dominant" "polytene chromosome,melanotic mass,embryonic/larval brain,salivary gland" FBgn0002649 Margin Margin http://flybase.net/reports/FBgn0002649.html gene Mar 16-Dec-15 2015_12 "lethal,recessive" wing FBgn0001387 l(1)2Bs lethal (1) 2Bs http://flybase.net/reports/FBgn0001387.html gene 16-Dec-15 2015_12 lethal FBgn0021934 l(2)k11009 lethal (2) k11009 http://flybase.net/reports/FBgn0021934.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040752 Prosap Prosap http://flybase.net/reports/FBgn0040752.html "FBgn0033895, FBgn0047309, FBgn0050483, FBgn0062213" protein_coding_gene "0030160=GKAP/Homer scaffold activity, 0005515=protein binding" 0097107=postsynaptic density assembly 0014069=postsynaptic density "anon-WO0118547.149, CG13354, ProSAP, Shank, BcDNA:GH23107, D-ProSAP, CG30483, CG8122" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR001452=SH3 domain, IPR011511=Variant SH3 domain, IPR001478=PDZ domain" CG30483 16-Dec-15 2015_12 "ENSDARG00000063054(shank3),ENSDARG00000063332" WBGene00006444(shn-1) "ENSXETG00000015689(),ENSXETG00000000210(SHANK1)" "ENSMUSG00000022623(Shank3),ENSMUSG00000037541(Shank2),ENSMUSG00000038738(Shank1)" "ENSG00000161681(SHANK1),ENSG00000162105(SHANK2)" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0032640 Sgt small glutamine-rich tetratricopeptide containing protein http://flybase.net/reports/FBgn0032640.html protein_coding_gene 0007274=neuromuscular synaptic transmission "CG5094, dsgt" "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR001440=Tetratricopeptide repeat 1, IPR019734=Tetratricopeptide repeat" CG5094 16-Dec-15 2015_12 "ENSDARG00000019941(zgc:55741),ENSDARG00000016769(sgta)" YOR007C(SGT2) WBGene00019893(sgt-1) "ENSXETG00000003714(sgta),ENSXETG00000000452(SGTB)" "ENSMUSG00000042743(Sgtb),ENSMUSG00000004937(Sgta)" "ENSG00000197860(SGTB),ENSG00000104969(SGTA)" viable DRSC02812 I -0.062351427 -2.370778344 -0.873431057 1.249921019 0.3761155 -0.086711019 FBgn0051703 CG31703 http://flybase.net/reports/FBgn0051703.html FBan0031703 protein_coding_gene 0003677=DNA binding "0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter" 0016593=Cdc73/Paf1 complex "IPR031102=RNA polymerase-associated protein Rtf1, IPR004343=Plus-3 domain" CG31703 16-Dec-15 2015_12 FBgn0283435 CR46279 http://flybase.net/reports/FBgn0283435.html pseudogene_attribute CG12717-related CR46279 16-Dec-15 2015_12 FBgn0264525 ff12 http://flybase.net/reports/FBgn0264525.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" FBgn0262484 CG43074 http://flybase.net/reports/FBgn0262484.html protein_coding_gene CG43074 16-Dec-15 2015_12 FBgn0020804 ms(3)A81 ms(3)A81 http://flybase.net/reports/FBgn0020804.html gene 3-A81 16-Dec-15 2015_12 "male sterile,recessive,female sterile,partially,chemical sensitive" FBgn0015827 T-D14.1 T-D14.1 http://flybase.net/reports/FBgn0015827.html gene 16-Dec-15 2015_12 FBgn0263077 CG43340 http://flybase.net/reports/FBgn0263077.html "FBgn0050492, FBan0030492, FBgn0263045, FBgn0027604, FBgn0050494, FBgn0033197, FBgn0033198, FBgn0040781, FBgn0063175" protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis "BcDNA:GH02712, CT6764, BcDNA:HL07907, CG30492, CG2080, CG2088, CG17984, CG17983, CG30494" "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG43340 16-Dec-15 2015_12 FBgn0033130 Tsp42Ei Tetraspanin 42Ei http://flybase.net/reports/FBgn0033130.html protein_coding_gene 0016021=integral component of membrane "Tsp42EI, tetraspanin 42E, CG12843, Dm.Tsp42Ei" "IPR008952=Tetraspanin, EC2 domain, IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin" CG12843 16-Dec-15 2015_12 "viable,fertile" FBgn0266429 AstA-R1 Allatostatin A receptor 1 http://flybase.net/reports/FBgn0266429.html "FBgn0266387, FBgn0028961, FBgn0024990, FBgn0040320" protein_coding_gene "0008188=neuropeptide receptor activity, 0004930=G-protein coupled receptor activity, 0008261=allatostatin receptor activity" "0007218=neuropeptide signaling pathway, 0007186=G-protein coupled receptor signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "CG2872, AST-R, GR, AlstR, DAR-1, DGR, Allatostatin Receptor, ASA-receptor, D.AlstR1, ASR, Galanin Receptor, DAR1, EG:121E7.2" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR000405=Galanin receptor family, IPR017452=GPCR, rhodopsin-like, 7TM" CG2872 16-Dec-15 2015_12 "ENSDARG00000067563(kiss1rb),ENSDARG00000002728(kiss1ra)" WBGene00013974(npr-9) "ENSXETG00000012621(GALR2),ENSXETG00000009147(),ENSXETG00000006335(),ENSXETG00000014693(GALR1)" "ENSMUSG00000020793(Galr2),ENSMUSG00000047429(Galr3),ENSMUSG00000024553(Galr1)" "ENSG00000166573(GALR1),ENSG00000182687(GALR2)" FBgn0034262 swi2 swi2 http://flybase.net/reports/FBgn0034262.html protein_coding_gene "0035556=intracellular signal transduction, 0035075=response to ecdysone, 0035073=pupariation" CG14485 CG14485 16-Dec-15 2015_12 viable FBgn0053769 CG33769 http://flybase.net/reports/FBgn0053769.html FBgn0037173 protein_coding_gene CG14458 "IPR010512=Protein of unknown function DUF1091, IPR006617=Protein of unknown function DM8" CG33769 16-Dec-15 2015_12 FBgn0262769 Su(E1)-C http://flybase.net/reports/FBgn0262769.html gene 16-Dec-15 2015_12 FBgn0005203 l(3)bt lethal brain tumor http://flybase.net/reports/FBgn0005203.html gene "lethal (3) brain tumor, l(2)brain tumor" 16-Dec-15 2015_12 "tumorigenic,lethal,heat sensitive" "embryonic/larval brain,heat sensitive" FBgn0020835 l(2)M7 Massachusetts 7 http://flybase.net/reports/FBgn0020835.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005262 l(3)SG82 lethal (3) SG82 http://flybase.net/reports/FBgn0005262.html gene 16-Dec-15 2015_12 "lethal,recessive,heat sensitive" FBgn0011108 l(1)Q69 lethal (1) Q69 http://flybase.net/reports/FBgn0011108.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0000424 de deacon http://flybase.net/reports/FBgn0000424.html gene 16-Dec-15 2015_12 visible "wing,adult thorax,adult abdomen,eye" FBgn0005340 Rf-c Roof c http://flybase.net/reports/FBgn0005340.html gene Roof-c 16-Dec-15 2015_12 wing FBgn0034543 CG30152 http://flybase.net/reports/FBgn0034543.html FBgn0050152 protein_coding_gene "FAM96a, CG10404, Cg30152" IPR002744=Domain of unknown function DUF59 CG30152 16-Dec-15 2015_12 ENSMUSG00000032381(Fam96a) ENSG00000166797(FAM96A) "viable,lethal" FBgn0082332 HM804 HM804 http://flybase.net/reports/FBgn0082332.html gene 16-Dec-15 2015_12 FBgn0263906 l(3)F582 http://flybase.net/reports/FBgn0263906.html gene 16-Dec-15 2015_12 "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0040949 CG13998 http://flybase.net/reports/FBgn0040949.html protein_coding_gene 0007305=vitelline membrane formation involved in chorion-containing eggshell formation 0042600=chorion CG13998 16-Dec-15 2015_12 viable DRSC02330 K -0.295862336 -0.063338005 -0.046679701 0.558545054 0.021816116 1.749932245 FBgn0011893 tRNA:K2:42Eb transfer RNA:lys2:42Eb http://flybase.net/reports/FBgn0011893.html "FBgn0003796, FBgn0011886, FBgn0050301, FBgn0060181" tRNA_gene "0033444=AAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:K2, tRNA[Lys][[2]], tRNA:lys2:42Eb, chr2R.trna90-LysCTT, AE002778.trna3-LysCTT, CR30301, tRNAlys, tRNA:K:CTT:AE002778-c" CR30301 16-Dec-15 2015_12 FBgn0069425 JJF024 JJF024 http://flybase.net/reports/FBgn0069425.html gene 16-Dec-15 2015_12 stress response defective FBgn0053496 CR33496 http://flybase.net/reports/FBgn0053496.html pseudogene_attribute CG33496 CR33496 16-Dec-15 2015_12 "ENSDARG00000053593(LOC100329372),ENSDARG00000013335(LOC100333447)" FBgn0003523 Ste Stellate http://flybase.net/reports/FBgn0003523.html FBgn0063181 protein_coding_gene 0019887=protein kinase regulator activity 0007283=spermatogenesis "0005737=cytoplasm, 0005956=protein kinase CK2 complex, 0005634=nucleus" "eSte, stellate, ste, euchromatic Stellate, CG32605, euSte, BcDNA:GM31840, Ste eu, euchromatic Ste" "IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR000704=Casein kinase II, regulatory subunit" 16-Dec-15 2015_12 "viable,fertile" spermatocyte FBgn0031052 CG14215 http://flybase.net/reports/FBgn0031052.html protein_coding_gene IPR025151=ELYS-like domain CG14215 16-Dec-15 2015_12 ENSMUSG00000026491(Ahctf1) ENSG00000153207(AHCTF1) "viable,fertile" FBgn0262323 mir-252 mir-252 stem loop http://flybase.net/reports/FBgn0262323.html miRNA_gene 0007517=muscle organ development "dme-miR-252-5p, CR43030, miR-252, 252, dme-miR-252, dme-mir-252" CR43030 16-Dec-15 2015_12 "lethal,visible" "eye,wing,wing vein,wing vein L5,wing margin,wing margin bristle" FBgn0010357 ë_Try ë_Trypsin http://flybase.net/reports/FBgn0010357.html FBgn0033622 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "beta, betaTry, CG18211, SP119, betaTrypsin, Try, DmBetaTry" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG18211 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" " larval stage | third instar , adult stage " larval digestive system | restricted

viable FBgn0058203 CG40203 http://flybase.net/reports/FBgn0058203.html FBan0040203 protein_coding_gene 16-Dec-15 2015_12 FBgn0028574 pp45 pp45 http://flybase.net/reports/FBgn0028574.html gene 16-Dec-15 2015_12 FBgn0000400 cvw convexwing http://flybase.net/reports/FBgn0000400.html gene convex wing 16-Dec-15 2015_12 "viable,fertile,visible,recessive" "wing,tergite,female,microchaeta & adult abdomen | female" FBgn0264974 rho::ru http://flybase.net/reports/FBgn0264974.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0001757 l(1)M5 lethal (1) M5 http://flybase.net/reports/FBgn0001757.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039659 CG14506 http://flybase.net/reports/FBgn0039659.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" cg14506 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG14506 16-Dec-15 2015_12 "viable,fertile" FBgn0029526 CR18166 http://flybase.net/reports/FBgn0029526.html FBgn0043840 pseudogene_attribute "CG18166, CG13372, BEST:GH02584" CR18166 16-Dec-15 2015_12 DRSC17249 E -1.374136868 0.977437101 1.78543844 -0.156882764 -0.079455441 -0.104201653 FBgn0259737 CG42391 http://flybase.net/reports/FBgn0259737.html protein_coding_gene CG42391 16-Dec-15 2015_12 WBGene00019483(K07D4.2) FBgn0264902 CR44093 http://flybase.net/reports/FBgn0264902.html non_protein_coding_gene CR44093 16-Dec-15 2015_12 FBgn0031621 Elba3 Early boundary activity 3 http://flybase.net/reports/FBgn0031621.html protein_coding_gene "0030674=protein binding, bridging" 0031937=positive regulation of chromatin silencing "0005677=chromatin silencing complex, 0005634=nucleus" "CG15634, early boundary factor, Elba" CG15634 16-Dec-15 2015_12 viable FBgn0001541 l(1)14DEc lethal (1) 14DEc http://flybase.net/reports/FBgn0001541.html gene 16-Dec-15 2015_12 lethal FBgn0028351 l(1)G0167 lethal (1) G0167 http://flybase.net/reports/FBgn0028351.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0023081 gek genghis khan http://flybase.net/reports/FBgn0023081.html "FBgn0010655, FBgn0044829, FBgn0061181" protein_coding_gene "0019992=diacylglycerol binding, 0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0008039=synaptic target recognition, 0008154=actin polymerization or depolymerization, 0008064=regulation of actin polymerization or depolymerization, 0035556=intracellular signal transduction, 0006468=protein phosphorylation" "0030426=growth cone, 0030424=axon" "Genghis Kahn, Genghis khan, l(2)09373, MRCKalpha, anon-WO0200864.1, Mrck, Myotonic dystrophy kinase related, CG4012, MdaPk, chingis khan, Gek, dMRCK" "IPR014930=Myotonic dystrophy protein kinase, coiled coil, IPR001180=Citron homology (CNH) domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001849=Pleckstrin homology domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR017892=Protein kinase, C-terminal, IPR000095=CRIB domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG4012 16-Dec-15 2015_12 "ENSDARG00000058760,ENSDARG00000016464(zgc:174985),ENSDARG00000019383(cdc42bpb)" WBGene00006437(mrck-1) "ENSXETG00000022112(CDC42BPA),ENSXETG00000023097(CDC42BPG)" "ENSMUSG00000026490(Cdc42bpa),ENSMUSG00000021279(Cdc42bpb)" "ENSG00000143776(CDC42BPA),ENSG00000198752(CDC42BPB),ENSG00000171219(CDC42BPG)" "neuroanatomy defective,recessive,somatic clone,viable,visible,fertile,lethal,maternal effect,wild-type,lethal - all die before end of larval stage,some die during larval stage" "eye photoreceptor cell,somatic clone,lamina plexus,lamina,growth cone,eye,embryonic/larval optic stalk,photoreceptor cell R7,eye photoreceptor cell | third instar larval stage,embryonic/larval optic stalk | third instar larval stage,lamina | third instar larval stage,eye | adult stage,embryonic/first instar larval cuticle,maternal effect" FBgn0000019 abr abero http://flybase.net/reports/FBgn0000019.html gene 16-Dec-15 2015_12 "viable,poor,visible,recessive" "ommatidium,abdomen,macrochaeta,microchaeta,wing,anterior dorsocentral bristle" FBgn0019809 gcm2 gcm2 http://flybase.net/reports/FBgn0019809.html FBgn0032133 protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0042690=negative regulation of crystal cell differentiation, 0030182=neuron differentiation, 0008283=cell proliferation, 0035165=embryonic crystal cell differentiation, 0042387=plasmatocyte differentiation, 0042063=gliogenesis, 0042688=crystal cell differentiation, 0048813=dendrite morphogenesis, 0021782=glial cell development, 0035164=embryonic plasmatocyte differentiation, 0006355=regulation of transcription, DNA-templated, 0010001=glial cell differentiation" 0005634=nucleus "glide2, CG3858, dGCM2, Gcm2, glide glide2, glial cells missing 2, FBgn0019809" IPR003902=Transcription regulator GCM domain CG3858 16-Dec-15 2015_12 ENSDARG00000045413(gcm2) ENSXETG00000027375(GCM1) ENSMUSG00000023333(Gcm1) ENSG00000124827(GCM2) " embryonic stage | stage 12-15 , embryonic stage | stage 5-11 , embryonic stage | stage 9-11 " " lateral ectoderm

, head mesoderm

, CNS glial cell | subset

, interface glial cell

, neuroblast NB1-3

" "neuroanatomy defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "dorsal multidendritic neuron ddaD,abdominal ventral multidendritic neuron v'dap,crystal cell primordium,crystal cell,embryonic/larval glial cell,ectopic,glial cell,outer photoreceptor cell,somatic clone,optic lobe,medulla cortex & glial cell | somatic clone" FBgn0053666 CG33666 http://flybase.net/reports/FBgn0053666.html protein_coding_gene CG33666 16-Dec-15 2015_12 FBgn0262568 CG43108 http://flybase.net/reports/FBgn0262568.html protein_coding_gene lincRNA.338 CG43108 16-Dec-15 2015_12 FBgn0069429 JJF007 JJF007 http://flybase.net/reports/FBgn0069429.html gene 16-Dec-15 2015_12 stress response defective FBgn0065514 l(2)SH1156 lethal (2) SH1156 http://flybase.net/reports/FBgn0065514.html gene l(2)SH2 1156 16-Dec-15 2015_12 "lethal,recessive" FBgn0000069 Alp Abnormal leg pattern http://flybase.net/reports/FBgn0000069.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,sex comb,metatarsus,tarsal segment 2" FBgn0261940 robo1::robo2 http://flybase.net/reports/FBgn0261940.html engineered_fusion_gene "Robo1:2, Robo2:1, robo::lea" 16-Dec-15 2015_12 neuroanatomy defective "longitudinal connective,tract,ectopic | embryonic stage" FBgn0039413 CG14556 http://flybase.net/reports/FBgn0039413.html protein_coding_gene CG14556 16-Dec-15 2015_12 FBgn0267008 CR45452 http://flybase.net/reports/FBgn0267008.html non_protein_coding_gene CR45452 16-Dec-15 2015_12 FBgn0263118 tx taxi http://flybase.net/reports/FBgn0263118.html "FBgn0008649, FBgn0003904" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0070888=E-box binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043425=bHLH transcription factor binding, 0046982=protein heterodimerization activity" "0007474=imaginal disc-derived wing vein specification, 0007525=somatic muscle development, 0033627=cell adhesion mediated by integrin, 0006355=regulation of transcription, DNA-templated, 0007498=mesoderm development, 0016203=muscle attachment" 0005634=nucleus "Dei, CG5441, taxi wings, bHLHc10, Delilah, delilah, dei, del" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG5441 16-Dec-15 2015_12 "ENSDARG00000056130(neurog1),ENSDARG00000016951" "ENSMUSG00000027967(Neurog2),ENSMUSG00000048904(Neurog1),ENSMUSG00000044312(Neurog3)" DRSC16931 E 0.489344248 0.145368523 2.07876987 -0.764703101 0.402146852 0.5388644 FBgn0034159 CG15615 http://flybase.net/reports/FBgn0034159.html protein_coding_gene IPR009078=Ferritin-like superfamily CG15615 16-Dec-15 2015_12 "ENSXETG00000006596(),ENSXETG00000010614(),ENSXETG00000000005()" DRSC06568 I 0.521183675 -2.149566102 0.391009478 -0.426665101 0.129843834 -0.578738269 FBgn0052549 CG32549 http://flybase.net/reports/FBgn0052549.html "FBgn0030916, FBgn0030917, FBgn0040879" protein_coding_gene 0008253=5'-nucleotidase activity 0006139=nucleobase-containing compound metabolic process 0005829=cytosol "CG6278, CG6267, 24643016, 45555989, 24643014, 45555998, CG6247" "IPR008380=HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase, IPR016695=Purine 5'-nucleotidase, IPR023214=HAD-like domain" CG32549 16-Dec-15 2015_12 "ENSDARG00000058231(nt5c2b),ENSDARG00000039399(nt5c2a),ENSDARG00000034852(nt5c2l1)" WBGene00022201(Y71H10B.1) ENSXETG00000018955(NT5DC4) ENSMUSG00000025041(Nt5c2) ENSG00000076685(NT5C2) "viable,fertile" FBgn0029651 CG10782 http://flybase.net/reports/FBgn0029651.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001310 kk kinky http://flybase.net/reports/FBgn0001310.html gene 16-Dec-15 2015_12 visible macrochaeta FBgn0260944 Rbp1 RNA-binding protein 1 http://flybase.net/reports/FBgn0260944.html "FBgn0010252, FBgn0010254" protein_coding_gene "0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0045292=mRNA cis splicing, via spliceosome, 0008380=RNA splicing, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0031440=regulation of mRNA 3'-end processing, 0000398=mRNA splicing, via spliceosome, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0010468=regulation of gene expression, 0006376=mRNA splice site selection" "0005634=nucleus, 0035327=transcriptionally active chromatin" "rbp1, Rbp1D, rrm11, RRM1, RNA-binding protein 11, Rbp11, Rbp-1, CG17136, RRM11, RBP1, rrm1" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG17136 16-Dec-15 2015_12 "ENSDARG00000025397(sfrs3a),ENSDARG00000059360(sfrs3b)" "ENSMUSG00000078134,ENSMUSG00000071172(Srsf3)" " adult stage , larval stage | third instar , embryonic stage -- adult stage , pupal stage " FBgn0065671 l(2)SH0682 lethal (2) SH0682 http://flybase.net/reports/FBgn0065671.html gene l(2)SH2 0682 16-Dec-15 2015_12 "lethal,recessive" FBgn0067338 mir-60 mir-60 http://flybase.net/reports/FBgn0067338.html miRNA_gene miR-60 16-Dec-15 2015_12 FBgn0267895 CR46183 http://flybase.net/reports/FBgn0267895.html pseudogene_attribute CG12717-related CR46183 16-Dec-15 2015_12 FBgn0011279 Obp69a Odorant-binding protein 69a http://flybase.net/reports/FBgn0011279.html protein_coding_gene "0005549=odorant binding, 0008145=phenylalkylamine binding, 0005550=pheromone binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "pbprp1, Pbprp1, PBP1, DmelObp69a, CG10436, pbprp-1, Obp69a, 69a, PB-PRP1, PBPRP-1, Pheromone-binding protein-related protein 1" IPR006170=Pheromone/general odorant binding protein CG10436 16-Dec-15 2015_12 adult stage " sensillum trichodeum of antennal segment 3

, antennal segment 3 | anterior

" viable embryonic/larval hemocyte | third instar larval stage FBgn0011627 l(2)T56j7 lethal (2) T56j7 http://flybase.net/reports/FBgn0011627.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0053052 CG33052 http://flybase.net/reports/FBgn0053052.html FBgn0036719 protein_coding_gene CG3882 IPR007033=RAB6-interacting golgin CG33052 16-Dec-15 2015_12 ENSMUSG00000040124(Gorab) viable FBgn0001269 inv invected http://flybase.net/reports/FBgn0001269.html protein_coding_gene 0043565=sequence-specific DNA binding "0050832=defense response to fungus, 0048100=wing disc anterior/posterior pattern formation, 0007474=imaginal disc-derived wing vein specification, 0007400=neuroblast fate determination, 0007476=imaginal disc-derived wing morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0007386=compartment pattern specification" 0005634=nucleus "engrailed-invected, Engrailed/Invected, Inv, er, IV, engrailed-related, CG17835, in, Invected, transcript group IV" "IPR019737=Homeobox engrailed-type, conserved site, IPR019549=Homeobox engrailed, C-terminal, IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif, IPR020479=Homeodomain, metazoa, IPR000747=Homeodomain engrailed, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG17835 16-Dec-15 2015_12 "ENSG00000163064(EN1),ENSG00000164778(EN2)" " embryonic stage | contracted germ band , embryonic stage | extended germ band , embryonic stage | stage 13 , larval stage | third instar " " inclusive hindgut primordium

, organism | segmentally repeated

,organism | segmentally repeated & posterior compartment , dorsal mesothoracic disc | posterior compartment

" "visible,dominant,immune response defective,viable,homeotic,heat sensitive" "wing,segment,cuticle,denticle belt,wing vein,ectopic,anterior/posterior compartment boundary,longitudinal connective,commissure,presumptive embryonic/larval muscle system,embryonic hindgut,anterior crossvein,wing vein L1,wing vein L2,anterior" FBgn0052690 CR32690 http://flybase.net/reports/FBgn0052690.html FBgn0045768 non_protein_coding_gene "BEST:LP10814, CG32690" CR32690 16-Dec-15 2015_12 FBgn0036829 Ir75d Ionotropic receptor 75d http://flybase.net/reports/FBgn0036829.html protein_coding_gene "0015276=ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" 0050907=detection of chemical stimulus involved in sensory perception "0016021=integral component of membrane, 0016020=membrane" "ionotropic receptor 75d, IR75d, DmelIR75d, lr75d, CT33663, CG14076" IPR001320=Ionotropic glutamate receptor CG14076 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0040373 CG3038 http://flybase.net/reports/FBgn0040373.html FBgn0029515 protein_coding_gene "0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, 0016757=transferase activity, transferring glycosyl groups" 0006486=protein glycosylation 0016020=membrane "EG:BACR37P7.1, GalT3, dbeta3GnT" "IPR002659=Glycosyl transferase, family 31" CG3038 16-Dec-15 2015_12 "viable,fertile" FBgn0034284 CG14491 http://flybase.net/reports/FBgn0034284.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG14491 16-Dec-15 2015_12 FBgn0045057 fs(1)164 female sterile (1) 164 http://flybase.net/reports/FBgn0045057.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "nurse cell & nucleus,egg chamber" FBgn0035956 Doc2 Dorsocross2 http://flybase.net/reports/FBgn0035956.html protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0061327=anterior Malpighian tubule development, 0035051=cardiocyte differentiation, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG5187, Doc, dorsocross, Dm-DOC2, doc2, Dorsocross" "IPR001699=Transcription factor, T-box, IPR002070=Transcription factor, Brachyury, IPR008967=p53-like transcription factor, DNA-binding, IPR018186=Transcription factor, T-box, conserved site" CG5187 16-Dec-15 2015_12 WBGene00006543(tbx-2) ENSXETG00000004260(TEgg048b09.1) ENSMUSG00000030699(Tbx6) embryonic stage--pupal stage " embryonic stage , embryonic stage | stage 9-16 , embryonic stage | stage 15-16 , embryonic stage | stage 5-15 , embryonic stage | stage 5-11 " " cardioblast | subset

, parasegment && ectoderm && mesoderm | dorsal & restricted

, embryonic anterior Malpighian tubule

, amnioserosa

, organism | dorso-lateral

, abdominal lateral pentascolopidial chordotonal organ lch5

, mesoderm | restricted

, dorsal pouch

, procephalic neurogenic region

" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,viable" "wing vein,ectopic,wing,extended germ band embryo,embryonic pericardial cell,cardioblast,supernumerary,somatic mesoderm,distal,leg,arista" FBgn0051809 CG31809 http://flybase.net/reports/FBgn0051809.html protein_coding_gene 0016229=steroid dehydrogenase activity 0008202=steroid metabolic process "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG31809 16-Dec-15 2015_12 YBR159W(IFA38) ENSMUSG00000034189(Hsdl1) ENSG00000103160(HSDL1) FBgn0038530 AttD Attacin-D http://flybase.net/reports/FBgn0038530.html protein_coding_gene "0050830=defense response to Gram-positive bacterium, 0019731=antibacterial humoral response" "0005576=extracellular region, 0031201=SNARE complex" "AttacinD, att, attacin D, Attacin D, CG7629, attacin-D, att D, Att, Attackin, attacin, attD, Attacin" "IPR005520=Attacin, N-terminal, IPR005521=Attacin, C-terminal" CG7629 16-Dec-15 2015_12 viable FBgn0038930 CG5778 http://flybase.net/reports/FBgn0038930.html FBgn0063252 protein_coding_gene "BcDNA:GH13168, CT18134" CG5778 16-Dec-15 2015_12 viable FBgn0040116 l(2)23Da lethal (2) 23Da http://flybase.net/reports/FBgn0040116.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0062667 EP3087 EP3087 http://flybase.net/reports/FBgn0062667.html gene EP(3)3087 16-Dec-15 2015_12 FBgn0038135 CG8773 http://flybase.net/reports/FBgn0038135.html protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" "0033227=dsRNA transport, 0006508=proteolysis" "IPR024571=ERAP1-like C-terminal domain, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase" CG8773 16-Dec-15 2015_12 ENSDARG00000057064 WBGene00011587(T07F10.1) ENSXETG00000013333(ENPEP) ENSMUSG00000028024(Enpep) ENSG00000138792(ENPEP) viable FBgn0028920 CG8997 http://flybase.net/reports/FBgn0028920.html protein_coding_gene "DS00941.12, CT25774, BG:DS00941.12" IPR010562=Haemolymph juvenile hormone binding CG8997 16-Dec-15 2015_12 viable FBgn0050120 CG30120 http://flybase.net/reports/FBgn0050120.html protein_coding_gene CG30120 16-Dec-15 2015_12 viable FBgn0038188 Art9 Arginine methyltransferase 9 http://flybase.net/reports/FBgn0038188.html protein_coding_gene 0016274=protein-arginine N-methyltransferase activity 0018216=peptidyl-arginine methylation 0005634=nucleus "DART9, CG9929" "IPR025799=Protein arginine N-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG9929 16-Dec-15 2015_12 viable FBgn0001669 l(1)EN5 lethal (1) from Eugene Nonautonomous 5 http://flybase.net/reports/FBgn0001669.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0016679 Mab3C7 Monoclonal antibody 3C7 http://flybase.net/reports/FBgn0016679.html gene 16-Dec-15 2015_12 FBgn0005330 P48 P48 http://flybase.net/reports/FBgn0005330.html gene 16-Dec-15 2015_12 optomotor response defective FBgn0039944 CG17162 http://flybase.net/reports/FBgn0039944.html "FBgn0022354, FBgn0058460, FBan0017162" protein_coding_gene "anon-20Ea, unnamed, CG40460, FBgn0058460" CG17162 16-Dec-15 2015_12 FBgn0013552 l(3)ry119 lethal (3) ry119 http://flybase.net/reports/FBgn0013552.html gene l(3)119 16-Dec-15 2015_12 "visible,recessive,partially lethal - majority die,lethal" eye FBgn0031651 mRpL24 mitochondrial ribosomal protein L24 http://flybase.net/reports/FBgn0031651.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005840=ribosome" "RpL24, L24, CG8849" "IPR005824=KOW, IPR003256=Ribosomal protein L24, IPR008991=Translation protein SH3-like domain, IPR014722=Ribosomal protein L2 domain 2, IPR005825=Ribosomal protein L24/L26, conserved site" CG8849 16-Dec-15 2015_12 ENSDARG00000019222(mrpl24) WBGene00019076(F59A3.3) ENSXETG00000018514(Q6DEN6_XENTR) ENSMUSG00000019710(Mrpl24) ENSG00000143314(MRPL24) "viable,visible" trichogen cell FBgn0037786 CG5361 http://flybase.net/reports/FBgn0037786.html protein_coding_gene 0004035=alkaline phosphatase activity 0008152=metabolic process "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase, IPR017850=Alkaline-phosphatase-like, core domain" CG5361 16-Dec-15 2015_12 FBgn0036765 CG7408 http://flybase.net/reports/FBgn0036765.html protein_coding_gene 0003943=N-acetylgalactosamine-4-sulfatase activity "0008152=metabolic process, 0042742=defense response to bacterium" "IPR017850=Alkaline-phosphatase-like, core domain, IPR000917=Sulfatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR024607=Sulfatase, conserved site" CG7408 16-Dec-15 2015_12 ENSDARG00000063359(LOC563783) WBGene00006310(sul-3) "ENSXETG00000015525(ARSJ),ENSXETG00000000542(ARSB),ENSXETG00000011881(ARSI)" "ENSMUSG00000042082(Arsb),ENSMUSG00000036412(Arsi),ENSMUSG00000046561(Arsj)" "ENSG00000183876(ARSI),ENSG00000113273(ARSB),ENSG00000180801(ARSJ)" "viable,fertile" FBgn0050046 CG30046 http://flybase.net/reports/FBgn0050046.html FBgn0033711 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "CT39323, CG17740" "IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR002861=Reeler domain, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR009465=Spondin, N-terminal" CG30046 16-Dec-15 2015_12 "ENSDARG00000023694(spon1b),ENSDARG00000010029(spon1a)" ENSXETG00000009063(SPON1) ENSMUSG00000038156(Spon1) ENSG00000152268(SPON1) viable FBgn0034921 DCP1 Decapping protein 1 http://flybase.net/reports/FBgn0034921.html FBgn0062201 protein_coding_gene "0005515=protein binding, 0050072=m7G(5')pppN diphosphatase activity" "0035195=gene silencing by miRNA, 0045451=pole plasm oskar mRNA localization, 0000956=nuclear-transcribed mRNA catabolic process, 2000637=positive regulation of gene silencing by miRNA, 0010603=regulation of cytoplasmic mRNA processing body assembly, 0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" "0005737=cytoplasm, 0000932=cytoplasmic mRNA processing body, 0043186=P granule" "DCP1, anon-WO0118547.163, CG11183, dDCP1, Dcp1, Dcp-1, Dcp1p, dDcp1" "IPR010334=Dcp1-like decapping, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG11183 16-Dec-15 2015_12 ENSDARG00000045484(LOC568176) WBGene00021929(dcap-1) "ENSXETG00000000899(DCP1B),ENSXETG00000015662(DCP1A)" ENSMUSG00000041477(Dcp1b) ENSG00000151065(DCP1B) "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,germline clone,maternal effect,female sterile,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "egg chamber,germline clone,cytoplasmic mRNA processing body, with DCP1tT2.R57A,embryonic abdominal segment,maternal effect,embryo,anterior,pole cell,cytoplasmic mRNA processing body, with DCP1442P" DRSC04091 K 0.69075801 0.550145052 0.586366348 -0.336515974 -1.968295973 -0.020591001 FBgn0065810 l(2)SH0386 lethal (2) SH0386 http://flybase.net/reports/FBgn0065810.html gene l(2)SH2 0386 16-Dec-15 2015_12 "lethal,recessive" FBgn0010157 logo longitudinal gone http://flybase.net/reports/FBgn0010157.html gene 16-Dec-15 2015_12 longitudinal connective FBgn0263414 CR43460 http://flybase.net/reports/FBgn0263414.html non_protein_coding_gene CR43460 16-Dec-15 2015_12 FBgn0065173 l(3)SH019 lethal (3) SH019 http://flybase.net/reports/FBgn0065173.html gene l(2)SH3 019 16-Dec-15 2015_12 "lethal,recessive" FBgn0065524 l(2)SH1121 lethal (2) SH1121 http://flybase.net/reports/FBgn0065524.html gene l(2)SH2 1121 16-Dec-15 2015_12 "lethal,recessive" FBgn0005002 Cyd Curlyoid http://flybase.net/reports/FBgn0005002.html gene 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" wing FBgn0005110 Humeral-patch Humeral patch http://flybase.net/reports/FBgn0005110.html gene Hup 16-Dec-15 2015_12 FBgn0259466 EP-610 http://flybase.net/reports/FBgn0259466.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0065633 l(2)SH0775 lethal (2) SH0775 http://flybase.net/reports/FBgn0065633.html gene l(2)SH2 0775 16-Dec-15 2015_12 "lethal,recessive" FBgn0029141 P(3)93B P(3)93B http://flybase.net/reports/FBgn0029141.html gene 16-Dec-15 2015_12 FBgn0084135 EP1410 EP1410 http://flybase.net/reports/FBgn0084135.html gene 16-Dec-15 2015_12 FBgn0034500 CG11200 Carbonyl reductase http://flybase.net/reports/FBgn0034500.html protein_coding_gene 0004090=carbonyl reductase (NADPH) activity 0008152=metabolic process 0012505=endomembrane system "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG11200 16-Dec-15 2015_12 YOR246C() ENSMUSG00000063897 viable FBgn0000760 fs(1)A475 female sterile (1) A475 http://flybase.net/reports/FBgn0000760.html gene 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive,lethal,rescuable maternal effect" FBgn0030877 Arp8 Actin-related protein 8 http://flybase.net/reports/FBgn0030877.html protein_coding_gene 0043140=ATP-dependent 3'-5' DNA helicase activity 0006338=chromatin remodeling "0005634=nucleus, 0031011=Ino80 complex" "arp8, CG7846, dArp8, actin related protein 8" "IPR004000=Actin family, IPR027668=Actin-related protein 8/Plant actin-related protein 9" CG7846 16-Dec-15 2015_12 YOR141C(ARP8) ENSMUSG00000015971(Actr8) ENSG00000113812(ACTR8) FBgn0023107 anon-13Fa anon-13Fa http://flybase.net/reports/FBgn0023107.html gene 16-Dec-15 2015_12 FBgn0019948 Phm Peptidylglycine-ë±-hydroxylating monooxygenase http://flybase.net/reports/FBgn0019948.html protein_coding_gene "0004504=peptidylglycine monooxygenase activity, 0005507=copper ion binding" "0055114=oxidation-reduction process, 0001519=peptide amidation, 0009620=response to fungus, 0032504=multicellular organism reproduction, 0007613=memory, 0006518=peptide metabolic process" "0016020=membrane, 0005615=extracellular space" "Peptidyl gycine alpha hydroxylating monooxygenase, PHM, Peptidylglycine-alpha-hydroxylating monooxygenase, peptidylglycine-alpha-hydroxylating monooxygenase, dPHM, CG3832, peptidylglycine alpha-hydroxylating monooxygenase" "IPR014783=Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site, IPR000323=Copper type II, ascorbate-dependent monooxygenase, N-terminal, IPR014784=Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR008977=PHM/PNGase F domain, IPR000720=Peptidyl-glycine alpha-amidating monooxygenase, IPR024548=Copper type II ascorbate-dependent monooxygenase, C-terminal" CG3832 16-Dec-15 2015_12 ENSDARG00000068342 WBGene00022144(Y71G12B.4) larval stage " larval central nervous system

, embryonic/larval endocrine system

, embryonic/larval digestive system

, SE2 neuron

" "lethal,recessive,partially,viable,memory defective" "mouthpart,supernumerary,puparium,pupa" FBgn0037960 mthl5 methuselah-like 5 http://flybase.net/reports/FBgn0037960.html "FBgn0046513, FBgn0046514" protein_coding_gene 0004930=G-protein coupled receptor activity "0042594=response to starvation, 0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan" 0016021=integral component of membrane "Mth-like 5, Mth-5, anon-WO0170980.70, CG6965, anon-WO0170980.71, mth-like 5" "IPR017981=GPCR, family 2-like, IPR000832=GPCR, family 2, secretin-like" CG6965 16-Dec-15 2015_12 viable FBgn0015275 Pc::Su(var)205 Pc::Su(var)205 http://flybase.net/reports/FBgn0015275.html engineered_fusion_gene "HP1-Polycomb, POLYCOMB/HP1" 16-Dec-15 2015_12 FBgn0260955 CG42587 http://flybase.net/reports/FBgn0260955.html protein_coding_gene CG42587 16-Dec-15 2015_12 FBgn0265268 CG18234 http://flybase.net/reports/FBgn0265268.html "FBgn0036794, FBgn0066943" protein_coding_gene "0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding, 0005506=iron ion binding" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum anon-SAGE:Wang-055 "IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG18234 16-Dec-15 2015_12 FBgn0036160 CG12289 http://flybase.net/reports/FBgn0036160.html FBgn0062516 protein_coding_gene "0008865=fructokinase activity, 0004454=ketohexokinase activity" 0046835=carbohydrate phosphorylation 0005737=cytoplasm BcDNA:AT04143 "IPR029056=Ribokinase-like, IPR011611=Carbohydrate kinase PfkB" CG12289 16-Dec-15 2015_12 ENSDARG00000029874(khk) ENSXETG00000001220(KHK) ENSMUSG00000029162(Khk) ENSG00000138030(KHK) viable FBgn0005365 UB597 UB597 http://flybase.net/reports/FBgn0005365.html gene 16-Dec-15 2015_12 eye FBgn0001714 l(1)ESHS35 lethal (1) ESHS35 http://flybase.net/reports/FBgn0001714.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267121 CR45561 http://flybase.net/reports/FBgn0267121.html non_protein_coding_gene CR45561 16-Dec-15 2015_12 FBgn0034240 MESR4 Misexpression suppressor of ras 4 http://flybase.net/reports/FBgn0034240.html "FBgn0043379, FBgn0043387" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "2001020=regulation of response to DNA damage stimulus, 0010468=regulation of gene expression, 0044255=cellular lipid metabolic process, 0046580=negative regulation of Ras protein signal transduction, 0071456=cellular response to hypoxia" "EP988, EP0988, EP(2)0988, Mesr4, misexpression suppressor of Ras4, Misexpression of Ras 4, EP0386, MSR4, CG4903" "IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR019787=Zinc finger, PHD-finger" CG4903 16-Dec-15 2015_12 "lethal,visible,mitotic cell cycle defective,viable,partially lethal - majority die" "adult abdomen & macrochaeta-537.4,tormogen cell,trichogen cell,ectopic,thecogen cell,dorsocentral bristle,scutellar bristle,wing" FBgn0010886 l(3)06404 lethal (3) 06404 http://flybase.net/reports/FBgn0010886.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000670 fliD flightless D http://flybase.net/reports/FBgn0000670.html gene 0007629=flight behavior 16-Dec-15 2015_12 "flightless,heat sensitive" FBgn0015493 l(3)65ACc lethal (3) 65ACc http://flybase.net/reports/FBgn0015493.html gene "Distal W5.4 Group III, III" 16-Dec-15 2015_12 "lethal,recessive" FBgn0052225 CG32225 http://flybase.net/reports/FBgn0052225.html protein_coding_gene 0016020=membrane IPR002000=Lysosome-associated membrane glycoprotein CG32225 16-Dec-15 2015_12 ENSXETG00000015086(C20orf103) viable FBgn0032087 CG9568 http://flybase.net/reports/FBgn0032087.html FBgn0044693 protein_coding_gene "FBgn 32087, anon-WO0140519.183" CG9568 16-Dec-15 2015_12 viable FBgn0013250 E(var)3-4 E(var)3-4 http://flybase.net/reports/FBgn0013250.html gene E-var(3)4 16-Dec-15 2015_12 "enhancer of variegation,dominant,suppressor of variegation" FBgn0000359 Cp36 Chorion protein 36 http://flybase.net/reports/FBgn0000359.html FBgn0000428 protein_coding_gene 0005213=structural constituent of chorion "0007306=eggshell chorion assembly, 0048477=oogenesis, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "Dms36, S36, cp36, CG1478, defective chorion 2, s365, dec[[2]], Shell-36, s36-1, dec2, dec-2, s36, CP36, E4, fs(1)C2" IPR008449=Chorion S36/S38 CG1478 16-Dec-15 2015_12 " oogenesis stage | stage S10-14 , adult stage && oogenesis stage | >=stage S10B " follicle cell

adult stage | female " ovary

{ v mus101K451 } , ovary

{ v fs(1)A1059K1 } , ovary

, ovary

{ 0 swa6 } " "female sterile,viable" "chorion,dorsal appendage,egg,maternal effect,chorion | maternal effect,endochorion,vitelline membrane" FBgn0264950 CR44119 http://flybase.net/reports/FBgn0264950.html non_protein_coding_gene CR44119 16-Dec-15 2015_12 FBgn0260812 inaF-D inaF-D http://flybase.net/reports/FBgn0260812.html "FBgn0023077, FBgn0046450, FBtr0073614, FBpp0073451, FBgn0260765" protein_coding_gene "0005246=calcium channel regulator activity, 0016247=channel regulator activity" "0016056=rhodopsin mediated signaling pathway, 0016058=maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling, 0009416=response to light stimulus, 0042391=regulation of membrane potential" 0016020=membrane "anon-WO0172774.148, CG2457, CG42563, InaF, inaF, INAF" "IPR029162=TRP-interacting helix, InaF motif" CG42563 16-Dec-15 2015_12 adult stage " eye

, head

" FBgn0011197 l(1)304-60 lethal (1) 304-60 http://flybase.net/reports/FBgn0011197.html FBgn0010203 gene 304-60 16-Dec-15 2015_12 "lethal,recessive" FBgn0032385 CG16964 http://flybase.net/reports/FBgn0032385.html FBgn0064974 protein_coding_gene BcDNA:GH05159 CG16964 16-Dec-15 2015_12 "viable,visible,planar polarity defective" trichogen cell FBgn0051524 CG31524 http://flybase.net/reports/FBgn0051524.html protein_coding_gene "0031418=L-ascorbic acid binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0005506=iron ion binding" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum "IPR013026=Tetratricopeptide repeat-containing domain, IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR011990=Tetratricopeptide-like helical domain, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR019734=Tetratricopeptide repeat" CG31524 16-Dec-15 2015_12 viable FBgn0051407 CG31407 http://flybase.net/reports/FBgn0051407.html "FBgn0045089, FBgn0045111" protein_coding_gene "NEST:bs35f01, NEST:bs33d08" CG31407 16-Dec-15 2015_12 viable FBgn0266896 CR45356 http://flybase.net/reports/FBgn0266896.html non_protein_coding_gene lincRNA.165 CR45356 16-Dec-15 2015_12 FBgn0082320 LpR2::Hsap\LRP1 LRP1 http://flybase.net/reports/FBgn0082320.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0036579 CG5027 http://flybase.net/reports/FBgn0036579.html protein_coding_gene "0003756=protein disulfide isomerase activity, 0005509=calcium ion binding" 0045454=cell redox homeostasis 0016021=integral component of membrane LD24073p "IPR001393=Calsequestrin, IPR013766=Thioredoxin domain, IPR017937=Thioredoxin, conserved site, IPR012336=Thioredoxin-like fold" CG5027 16-Dec-15 2015_12 ENSDARG00000038894(tmx3) WBGene00022836(ZK973.11) ENSXETG00000015637(TMX3) ENSMUSG00000024614(Tmx3) ENSG00000166479(TMX3) "viable,male semi-sterile,female semi-sterile,fertile" FBgn0028366 l(1)G0006 lethal (1) G0006 http://flybase.net/reports/FBgn0028366.html gene 16-Dec-15 2015_12 "lethal,recessive,male sterile" FBgn0065849 l(2)SH0309 lethal (2) SH0309 http://flybase.net/reports/FBgn0065849.html gene l(2)SH2 0309 16-Dec-15 2015_12 "lethal,recessive" FBgn0038405 CG8927 http://flybase.net/reports/FBgn0038405.html "FBtr0083254, FBpp0082708" protein_coding_gene 0042302=structural constituent of cuticle IPR000618=Insect cuticle protein CG8927 16-Dec-15 2015_12 viable FBgn0026391 Or33b Odorant receptor 33b http://flybase.net/reports/FBgn0026391.html protein_coding_gene "0004984=olfactory receptor activity, 0004888=transmembrane signaling receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "AN1, dor72, Or72, DOR33B.2, Or33B.2, Olfactory receptor 33B.2, 33b, CG16961, 33B.2, DOR72" "IPR004117=Olfactory receptor, Drosophila" CG16961 16-Dec-15 2015_12 sensory neuron &&of antennal segment 3

"smell perception defective,viable" FBgn0003553 Su(crc) Suppressor of cryptocephal http://flybase.net/reports/FBgn0003553.html gene Su(crc)1 16-Dec-15 2015_12 FBgn0003894 Tul Turneduplike http://flybase.net/reports/FBgn0003894.html gene 16-Dec-15 2015_12 FBgn0263460 snoRNA:CG31191-a http://flybase.net/reports/FBgn0263460.html snoRNA_gene snoHACA_06 CR43575 16-Dec-15 2015_12 FBgn0267570 CR45910 http://flybase.net/reports/FBgn0267570.html non_protein_coding_gene pri-mir-1000 CR45910 16-Dec-15 2015_12 FBgn0032587 CG5953 http://flybase.net/reports/FBgn0032587.html protein_coding_gene 0046331=lateral inhibition IPR006578=MADF domain CG5953 16-Dec-15 2015_12 "viable,fertile,lethal,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0000356 Cp16 Chorion protein 16 http://flybase.net/reports/FBgn0000356.html protein_coding_gene 0005213=structural constituent of chorion "0007306=eggshell chorion assembly, 0007275=multicellular organismal development, 0046843=dorsal appendage formation" 0042600=chorion "Dms16, Ov31, CP16, cp16, Chorion prot 16, s16-1, s16, S16, X16715, Chorion Protein 16, melcp16, CG6533" IPR008450=Chorion S16 CG6533 16-Dec-15 2015_12 " oogenesis stage | stage S11-14 , adult stage | female , adult stage && oogenesis stage | stage S13-14 " follicle cell

adult stage | female " ovary

, ovary

{ v mus101K451 } , ovary

{ 0 swa6 } , ovary

{ v fs(1)A1059K1 } " viable dorsal appendage DRSC25549 K -0.069607707 -0.21796029 -0.037792742 0.134395584 2.559367076 0.952596382 FBgn0051971 tRNA:CR31971 transfer RNA:CR31971 http://flybase.net/reports/FBgn0051971.html FBgn0011841 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2L.trna8-AspGTC, transfer RNA:asp2:25D, tRNA:asp2:25D, tRNA[[Asp]], tRNA:D2:25D, tRNA[Asp-GTC], CR31971" CR31971 16-Dec-15 2015_12 FBgn0014959 fod friend of diaphanous http://flybase.net/reports/FBgn0014959.html gene 16-Dec-15 2015_12 " adult stage | male , adult stage | female , spermatogenesis && adult stage " male germline stem cell

FBgn0026865 Helena\RTase Helena element reverse transcriptase http://flybase.net/reports/FBgn0026865.html transposable_element_gene 16-Dec-15 2015_12 FBgn0040794 CG13056 http://flybase.net/reports/FBgn0040794.html protein_coding_gene IPR007614=Retinin-like protein CG13056 16-Dec-15 2015_12 viable FBgn0039718 CG15517 http://flybase.net/reports/FBgn0039718.html protein_coding_gene CG15517 16-Dec-15 2015_12 "viable,visible,body color defective" mesothoracic tergum FBgn0026602 Ady43A Ady43A http://flybase.net/reports/FBgn0026602.html FBgn0033152 protein_coding_gene "0004001=adenosine kinase activity, 0016773=phosphotransferase activity, alcohol group as acceptor" "Adk43A, CG1851, ady43A, DmAdk3, Ady" "IPR029056=Ribokinase-like, IPR011611=Carbohydrate kinase PfkB, IPR002173=Carbohydrate/puine kinase, PfkB, conserved site" CG1851 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC05917 E -0.131282107 0.108905316 3.485213347 0.014319792 0.663603673 0.672466372 FBgn0032189 Ripë± RPA-interacting protein ë± http://flybase.net/reports/FBgn0032189.html protein_coding_gene "CG18145, dRIPalpha, Tes83, Ripalpha" "IPR028156=RPA-interacting protein, IPR028159=RPA-interacting protein, C-terminal domain" CG18145 16-Dec-15 2015_12 FBgn0011624 l(2)T56i24 lethal (2) T56i24 http://flybase.net/reports/FBgn0011624.html FBgn0005177 gene 16-Dec-15 2015_12 lethal FBgn0045443 mthl11 methuselah-like 11 http://flybase.net/reports/FBgn0045443.html FBgn0051147 protein_coding_gene 0004930=G-protein coupled receptor activity "0008340=determination of adult lifespan, 0042594=response to starvation, 0007186=G-protein coupled receptor signaling pathway" 0016021=integral component of membrane "Mth-like 11, Mth-like-11, CG31147" "IPR017981=GPCR, family 2-like, IPR010596=Methuselah, N-terminal domain, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR023311=Methuselah ectodomain, domain 2" CG31147 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" viable FBgn0011974 tRNA:S474:12Eh transfer RNA:ser474:12Eh http://flybase.net/reports/FBgn0011974.html "FBgn0003826, FBgn0011968, FBgn0052615, FBgn0060071" tRNA_gene "0033405=UCU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:S, Ser-tRNA-4-7, tRNA:ser474:12Eh, CR32615, tRNA[[Ser]], 474, AE002593.trna8-SerAGA, tRNA:S:AGA:AE002593-a, tRNA:ser, chrX.trna12-SerAGA, unnamed, transfer RNA:ser" CR32615 16-Dec-15 2015_12 FBgn0002386 l(3)93Db lethal (3) 93Db http://flybase.net/reports/FBgn0002386.html gene "er8, l(3)er8" 16-Dec-15 2015_12 "lethal,recessive" FBgn0262380 mir-309 mir-309 stem loop http://flybase.net/reports/FBgn0262380.html "FBgn0067695, FBgn0262196" miRNA_gene "CR42903, dme-mir-309, CR33613, miR-309, mir-309" CR42903 16-Dec-15 2015_12 viable FBgn0011881 tRNA:I:49Fa transfer RNA:ile:49Fa http://flybase.net/reports/FBgn0011881.html "FBgn0003788, FBgn0052839, FBgn0052842, FBgn0060201" tRNA_gene "0033433=AUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002787.trna18-IleAAT, tRNA:I:AAT:AE002787-a, tRNA[Ile], ile-a, tRNA:ile:49Fa, CR32839, CR32842, chr2R.trna77-IleAAT" CR32842 16-Dec-15 2015_12 FBgn0039920 CG11360 http://flybase.net/reports/FBgn0039920.html protein_coding_gene "0008270=zinc ion binding, 0044822=poly(A) RNA binding" "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus cg11360 "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG11360 16-Dec-15 2015_12 "ENSDARG00000058369(zgc:158350),ENSDARG00000039418" ENSXETG00000022367(rkhd1) "ENSMUSG00000048696(Mex3d),ENSMUSG00000057706,ENSMUSG00000037253(Mex3c)" "ENSG00000183496(MEX3B),ENSG00000176624(MEX3C),ENSG00000181588(MEX3D),ENSG00000203759" viable DRSC17134 K -0.333672061 1.108008442 0.543618397 -0.192115487 0.416747053 -1.69475814 FBgn0031101 CG1631 http://flybase.net/reports/FBgn0031101.html protein_coding_gene CG1631 16-Dec-15 2015_12 viable FBgn0000679 flrdB flight reduced B http://flybase.net/reports/FBgn0000679.html gene 0007629=flight behavior 16-Dec-15 2015_12 "jumping defective,flight defective" FBgn0012004 tRNA:V3b:92Bb transfer RNA:val3b:92Bb http://flybase.net/reports/FBgn0012004.html "FBgn0003855, FBgn0011997, FBgn0012005, FBgn0012006, FBgn0051430, FBgn0060021" tRNA_gene "0033452=GUG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:V:CAC:AE002708-b, tRNA:V3b:92Bc, tRNA:val3b:92Bb, AE002708.trna20-ValCAC, CR31430, transfer RNA:val3b:92Bc, tRNA:V3b, tRNA[Val][[3b]], tRNA:val3b:92Bc, tRNA:val3b:92Bd, transfer RNA:val3b:92Bd, valine tRNA, chr3R.trna26-ValCAC, tRNA:V3b:92Bd" CR31430 16-Dec-15 2015_12 FBgn0014046 Su(tor)2-187-3 Su(tor)2-187-3 http://flybase.net/reports/FBgn0014046.html gene 16-Dec-15 2015_12 FBgn0033315 ë_3GalTII Galactosyltransferase II http://flybase.net/reports/FBgn0033315.html protein_coding_gene 0008378=galactosyltransferase activity "0015012=heparan sulfate proteoglycan biosynthetic process, 0006486=protein glycosylation, 0030206=chondroitin sulfate biosynthetic process, 0006024=glycosaminoglycan biosynthetic process" 0016020=membrane "GalTII, dGAGbeta3GalTII, dbeta3GalTII, Galactosyltransferase II, CG8734" "IPR002659=Glycosyl transferase, family 31" CG8734 16-Dec-15 2015_12 ENSDARG00000038414(LOC572324) WBGene00005020(sqv-2) ENSXETG00000001036(b3galt6) ENSMUSG00000050796(B3galt6) ENSG00000176022(B3GALT6) "visible,viable" "wing,eye,interommatidial bristle" FBgn0040043 CG17643 http://flybase.net/reports/FBgn0040043.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005464 l(1)ts79 lethal (1) ts79 http://flybase.net/reports/FBgn0005464.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0061023 l(3)S025240 lethal (3) S025240 http://flybase.net/reports/FBgn0061023.html gene 0252/40 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031531 CG8840 http://flybase.net/reports/FBgn0031531.html protein_coding_gene CG8840 16-Dec-15 2015_12 viable FBgn0029573 CG14770 http://flybase.net/reports/FBgn0029573.html protein_coding_gene CG14770 16-Dec-15 2015_12 viable FBgn0262731 pncr013:4 putative noncoding RNA 013:4 http://flybase.net/reports/FBgn0262731.html "FBgn0041005, FBgn0053941, FBgn0063212, FBgn0086530" non_protein_coding_gene "MRE3, CR33941, CT32596, mRNA-like ncRNA in embryogenesis 3, BcDNA:GM01028, CG13303" CR33941 16-Dec-15 2015_12 FBgn0038692 CG3773 http://flybase.net/reports/FBgn0038692.html "FBgn0025224, FBgn0025225" protein_coding_gene "anon-EST:fe2D10, anon-fast-evolving-2D12, anon-fast-evolving-2D10, anon-EST:fe2D12, unnamed" CG3773 16-Dec-15 2015_12 ENSXETG00000026056() ENSMUSG00000032199(Grinl1a) lethal FBgn0060629 l(3)S086102b lethal (3) S086102b http://flybase.net/reports/FBgn0060629.html gene 0861/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0019877 anon-69Af anon-69Af http://flybase.net/reports/FBgn0019877.html gene 16-Dec-15 2015_12 larval stage--adult stage FBgn0014199 l(1)16Ff lethal (1) 16Ff http://flybase.net/reports/FBgn0014199.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "oogonial cell,germline clone,macrochaeta,wing vein" FBgn0010176 tu(1)R tu(1)R http://flybase.net/reports/FBgn0010176.html gene tu-R 16-Dec-15 2015_12 partially lethal - majority die macrochaeta FBgn0001070 Fs(3)Ven Female sterile (3) Vencellin http://flybase.net/reports/FBgn0001070.html gene "0009950=dorsal/ventral axis specification, 0046843=dorsal appendage formation" "Fs(3)Vencellin, Fs(3)Sz31" 16-Dec-15 2015_12 female sterile "egg,dorsal appendage" FBgn0044476 EP1321 EP1321 http://flybase.net/reports/FBgn0044476.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0003865 tsg twisted gastrulation http://flybase.net/reports/FBgn0003865.html FBgn0001519 protein_coding_gene 0008201=heparin binding "0030510=regulation of BMP signaling pathway, 0007354=zygotic determination of anterior/posterior axis, embryo, 0045165=cell fate commitment, 0017015=regulation of transforming growth factor beta receptor signaling pathway, 0010629=negative regulation of gene expression, 0007362=terminal region determination, 0008293=torso signaling pathway" 0005576=extracellular region "CG1502, RF32, l(1)11Ab, lethal(1)11Ac, Twisted gastrulation, l(1)tsg, l(1)RF32, Tsg, l(1)11Ac, dTsg" IPR006761=Twisted gastrulation (Tsg) protein CG1502 16-Dec-15 2015_12 ENSDARG00000033428 "ENSXETG00000004048(twsg1),ENSXETG00000014602(Q5FVZ5_XENTR)" ENSMUSG00000024098(Twsg1) ENSG00000128791(TWSG1) " embryonic stage | stage 4,5 , embryonic stage | stage 7 , embryonic stage | 1.5-3 hr , embryonic stage | stage 4-5 , embryonic stage | early " " parasegment 4--10 | dorsal

, posterior transverse furrow

, organism | 90-100% egg length

" "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,viable,lethal,wild-type,visible" "mitotic domain 1,mitotic domain 5,mitotic domain 6,salivary gland,embryo,amnioserosa,wing,wing vein,ectopic" FBgn0020279 lig lingerer http://flybase.net/reports/FBgn0020279.html FBgn0033253 protein_coding_gene 0005515=protein binding "0045571=negative regulation of imaginal disc growth, 0007620=copulation, 0060179=male mating behavior, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0045893=positive regulation of transcription, DNA-templated, 0046426=negative regulation of JAK-STAT cascade" "0000932=cytoplasmic mRNA processing body, 0005737=cytoplasm" "CG8715, transcription unit A, Lingerer" "IPR009060=UBA-like, IPR022166=Protein of unknown function DUF3697, ubiquitin-associated protein 2" CG8715 16-Dec-15 2015_12 "ENSDARG00000011396,ENSDARG00000060065(zgc:158399),ENSDARG00000063219(ubap2l)" "ENSXETG00000002157(),ENSXETG00000015342(UBAP2L)" "ENSMUSG00000042520(Ubap2l),ENSMUSG00000028433(Ubap2)" "ENSG00000137073(UBAP2),ENSG00000143569(UBAP2L)" "viable,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,recessive,mating defective,male,locomotor behavior defective,lethal - all die during pupal stage,male fertile,female fertile,reduced,lethal,size defective,somatic clone,nutrition conditional,increased cell death" "wing disc,eye,somatic clone,ommatidium,supernumerary,wing,nutrition conditional" DRSC07247 I -0.320694351 -2.586310091 -0.912449 1.146442677 -0.315473804 -0.87806481 FBgn0053356 5SrRNA-ë¬:CR33356 5SrRNA-ë¬:CR33356 http://flybase.net/reports/FBgn0053356.html pseudogene_attribute CR33356 CR33356 16-Dec-15 2015_12 FBgn0000130 Ars-region8 Autonomous replicating sequence region 8 http://flybase.net/reports/FBgn0000130.html region "ars413, Ars sequence 8, Ars8" 16-Dec-15 2015_12 FBgn0050338 CG30338 http://flybase.net/reports/FBgn0050338.html protein_coding_gene "IPR017359=Uncharacterised conserved protein UCP038021, RWD, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR010541=Domain of unknown function DUF1115, IPR006575=RWD domain" CG30338 16-Dec-15 2015_12 ENSDARG00000055426(si:dkey-177p2.14) "ENSXETG00000022672(RWDD2A),ENSXETG00000020254(RWDD2B)" "ENSMUSG00000032417(Rwdd2a),ENSMUSG00000041079(Rwdd2b)" "ENSG00000156253(RWDD2B),ENSG00000013392(RWDD2A)" viable FBgn0003730 ton tonochaetae http://flybase.net/reports/FBgn0003730.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced" "macrochaeta,eye,ommatidium,wing,wing vein,crossvein" FBgn0015422 l(1)17Da lethal (1) 17Da http://flybase.net/reports/FBgn0015422.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0019644 ATPsynB "ATP synthase, subunit B" http://flybase.net/reports/FBgn0019644.html protein_coding_gene "0046933=proton-transporting ATP synthase activity, rotational mechanism, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0006909=phagocytosis, 0015986=ATP synthesis coupled proton transport, 0015992=proton transport" "0005739=mitochondrion, 0005811=lipid particle, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATP syn-b, ATPsyn-b, Fo-ATP synthase subunit b, F0/F1 ATP synthase B, ATP synthase, b, ATPF, ATP synthase, subunit b, CG8189, ATP synthase B chain, ATP synthase B chain, mt precursor" "IPR008688=ATPase, F0 complex, B chain/subunit B/MI25, IPR013837=ATPase, F0 complex, B chain/subunit B" CG8189 16-Dec-15 2015_12 ENSDARG00000011553(atp5f1) YPL078C(ATP4) "WBGene00000207(asb-2),WBGene00000206(asb-1)" ENSXETG00000022255(atp5f1) ENSMUSG00000000563(Atp5f1) ENSG00000116459(ATP5F1) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC09659 E -1.159347393 -0.09285039 -0.192487128 -3.083890496 0.061939286 0.481505071 FBgn0259312 C762 http://flybase.net/reports/FBgn0259312.html gene 16-Dec-15 2015_12 visible wing vein FBgn0010785 l(3)02634 lethal (3) 02634 http://flybase.net/reports/FBgn0010785.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067086 JK1469 JK1469 http://flybase.net/reports/FBgn0067086.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0024667 l(2)k05001 lethal (2) k05001 http://flybase.net/reports/FBgn0024667.html gene 50/1 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0040890 ksh kish http://flybase.net/reports/FBgn0040890.html protein_coding_gene 0046907=intracellular transport "0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "CG14199, kish, ksh" IPR009653=Protein of unknown function DUF1242 CG14199 16-Dec-15 2015_12 ENSDARG00000059400(zgc:101127) YNL024C-A(KSH1) WBGene00010639(K07F5.15) ENSXETG00000027813(TNeu030j15.1) "ENSMUSG00000012422,ENSMUSG00000073376" ENSG00000174695(TMEM167A) lethal FBgn0031791 AANATL2 Arylalkylamine N-acyltransferase-like 2 http://flybase.net/reports/FBgn0031791.html protein_coding_gene "0004059=aralkylamine N-acetyltransferase activity, 0019186=acyl-CoA N-acyltransferase activity" "arylalkylamine N-acyltransferase-like 2, CG9486, AANATL2" "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG9486 16-Dec-15 2015_12 viable FBgn0065183 l(3)A143.1F3 lethal (3) A143.1F3 http://flybase.net/reports/FBgn0065183.html gene 16-Dec-15 2015_12 "lethal,partially,recessive" FBgn0015006 Abl::Hsap\ABL1 ABL1 http://flybase.net/reports/FBgn0015006.html engineered_fusion_gene 16-Dec-15 2015_12 wild-type FBgn0266653 CR45160 http://flybase.net/reports/FBgn0266653.html non_protein_coding_gene CR45160 16-Dec-15 2015_12 FBgn0051005 qless qless http://flybase.net/reports/FBgn0051005.html "FBgn0039834, FBgn0040627, FBgn0062019" protein_coding_gene 0000010=trans-hexaprenyltranstransferase activity "0008299=isoprenoid biosynthetic process, 0014019=neuroblast development, 0098780=response to mitochondrial depolarisation, 0043066=negative regulation of apoptotic process" "CG3684, CG31005, CG15565, anon-WO0118547.422" "IPR008949=Isoprenoid synthase domain, IPR000092=Polyprenyl synthetase, IPR017446=Polyprenyl synthetase-related" CG31005 16-Dec-15 2015_12 ENSDARG00000017910(pdss1) YBR003W(COQ1) WBGene00000761(coq-1) ENSXETG00000018798(PDSS1) ENSMUSG00000026784(Pdss1) ENSG00000148459(PDSS1) "neuroanatomy defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell death,stress response defective,hyperactive,dominant,uncoordinated,flightless" "embryonic/larval neuroblast,somatic clone" DRSC15103 E 0.445433751 -0.338554017 -1.591838408 -0.096138518 0.203029373 0.489316527 FBgn0028964 AER-d AER-d http://flybase.net/reports/FBgn0028964.html region 16-Dec-15 2015_12 FBgn0016666 Hrp54 Hrp54 http://flybase.net/reports/FBgn0016666.html gene 0003697=single-stranded DNA binding hrp54 16-Dec-15 2015_12 FBgn0015890 anon-75Cd anon-75Cd http://flybase.net/reports/FBgn0015890.html gene 16-Dec-15 2015_12 FBgn0014887 Su(phl)6 Suppressor of pole hole 6 http://flybase.net/reports/FBgn0014887.html gene "Suppressor of raf-like-oncogene, Su(D-raf)6" 16-Dec-15 2015_12 FBgn0262813 CG43184 http://flybase.net/reports/FBgn0262813.html protein_coding_gene chr3L_13830834_13831226.0 CG43184 16-Dec-15 2015_12 FBgn0066098 MCP-4.s MCP-4.s http://flybase.net/reports/FBgn0066098.html gene MCP-4 s 16-Dec-15 2015_12 FBgn0044873 E(Mer)IIb E(Mer)IIb http://flybase.net/reports/FBgn0044873.html gene "IIb, Group IIb" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,visible" "wing vein,ectopic" FBgn0002890 mus204 mutagen-sensitive 204 http://flybase.net/reports/FBgn0002890.html gene 16-Dec-15 2015_12 "female fertile,reduced,meiotic cell cycle defective,DNA repair defective,chemical sensitive,recessive,radiation sensitive" FBgn0082932 snoRNA:Me28S-G1083d snoRNA:Me28S-G1083d http://flybase.net/reports/FBgn0082932.html snoRNA_gene 0030562=rRNA 2'-O-ribose methylation guide activity 0000451=rRNA 2'-O-methylation 0005730=nucleolus "DmSnR60, CR34565, Me28S-Gm1083d, DmSnR60d" CR34565 16-Dec-15 2015_12 FBgn0267271 CR45707 http://flybase.net/reports/FBgn0267271.html non_protein_coding_gene CR45707 16-Dec-15 2015_12 FBgn0040485 BobC Brother of Bearded C http://flybase.net/reports/FBgn0040485.html FBgn0026561 gene 0005515=protein binding "Bob, Brother of Bearded, Bob-C" 16-Dec-15 2015_12 FBgn0037647 RagA-B Ras-related GTP binding A/B ortholog (H. sapiens) http://flybase.net/reports/FBgn0037647.html protein_coding_gene "0003924=GTPase activity, 0046982=protein heterodimerization activity, 0005525=GTP binding" "0010506=regulation of autophagy, 0032008=positive regulation of TOR signaling, 0009267=cellular response to starvation, 0030307=positive regulation of cell growth" "RagA, CG11968, Rag, dRagB, dRagA, Gtr1" "IPR006762=Gtr1/RagA G protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG11968 16-Dec-15 2015_12 YML121W(GTR1) WBGene00006414(raga-1) ENSXETG00000000887(rraga) "ENSMUSG00000070934(Rraga),ENSMUSG00000041658(Rragb)" "ENSG00000155876(RRAGA),ENSG00000083750(RRAGB)" "increased cell size,stress response defective,size defective,increased cell number,visible,decreased cell size,decreased cell number,viable" "wing,posterior compartment,autophagic vacuoleunspecified" FBgn0267261 CR45697 http://flybase.net/reports/FBgn0267261.html non_protein_coding_gene CR45697 16-Dec-15 2015_12 FBgn0024649 l(2)k09316 lethal (2) k09316 http://flybase.net/reports/FBgn0024649.html gene 93/16 16-Dec-15 2015_12 "lethal,recessive" FBgn0020660 eIF-4B Eukaryotic initiation factor 4B http://flybase.net/reports/FBgn0020660.html "FBgn0040057, FBan0010837" protein_coding_gene "0003743=translation initiation factor activity, 0000166=nucleotide binding, 0003729=mRNA binding" "0008283=cell proliferation, 0006413=translational initiation, 0046427=positive regulation of JAK-STAT cascade" 0005829=cytosol "eIF-4B-S, eIF-4B-L, eIF4B, eIF-4b, eIF4B-L, Eif4B, eIf4b, eIF4B-S, EIF-4B, CG10837, Dm-eIF4B" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG10837 16-Dec-15 2015_12 "ENSDARG00000017439(eif4ba),ENSDARG00000010194(eif4bb)" ENSXETG00000001829(eif4b) ENSMUSG00000058655(Eif4b) ENSG00000063046(EIF4B) "viable,cell lethal,conditional,cell growth defective,visible" "eye,ommatidium,chaeta,supernumerary" FBgn0005723 l(1)TK132 lethal (1) TK132 http://flybase.net/reports/FBgn0005723.html gene l132 16-Dec-15 2015_12 "lethal,recessive" lamina FBgn0022993 ors outer rhabdomeres small http://flybase.net/reports/FBgn0022993.html gene 16-Dec-15 2015_12 rhabdomere FBgn0261403 sxc super sex combs http://flybase.net/reports/FBgn0261403.html "FBgn0067375, FBgn0003658, FBgn0261392, FBgn0040295, FBan0010392, FBgn0027591" protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0016757=transferase activity, transferring glycosyl groups" "0006493=protein O-linked glycosylation, 0006486=protein glycosylation, 0045475=locomotor rhythm, 0035220=wing disc development" "l(2)NC130, dO-GnT, l(2)02637, Sxc, BcDNA:GH04245, O-linked N-acetylglucosamine transferase, O-glycosyltransferase, SXC, ogt, Ogt, CG10392, lethal (2) NC130, OGT, sxc/Ogt, P1201" "IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1, IPR011990=Tetratricopeptide-like helical domain, IPR029489=O-GlcNAc transferase, C-terminal, IPR013026=Tetratricopeptide repeat-containing domain" CG10392 16-Dec-15 2015_12 "ENSDARG00000057702(ogt.1),ENSDARG00000057705" WBGene00003858(ogt-1) ENSXETG00000023153(Q5BL53_XENTR) ENSMUSG00000034160(Ogt) ENSG00000147162(OGT) DRSC04911 E -1.095205936 -0.335277595 -1.981941137 0.199378581 0.589845769 -1.203506137 FBgn0024550 l(3)L3930 lethal (3) L3930 http://flybase.net/reports/FBgn0024550.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003712 thick thick http://flybase.net/reports/FBgn0003712.html gene tk 16-Dec-15 2015_12 visible "tarsal segment,leg,wing" FBgn0016729 Rst(2)Lb Resistance to Leptopilina boulardi http://flybase.net/reports/FBgn0016729.html gene "Rlb, rlb" 16-Dec-15 2015_12 FBgn0032218 CG5381 http://flybase.net/reports/FBgn0032218.html protein_coding_gene CG5381 16-Dec-15 2015_12 viable FBgn0011696 Pebp2ë_ Pebp2ë_ http://flybase.net/reports/FBgn0011696.html gene 0003713=transcription coactivator activity 0045944=positive regulation of transcription from RNA polymerase II promoter 0005634=nucleus 16-Dec-15 2015_12 FBgn0033842 cbc crowded by cid http://flybase.net/reports/FBgn0033842.html protein_coding_gene "0022008=neurogenesis, 0006388=tRNA splicing, via endonucleolytic cleavage and ligation, 0031124=mRNA 3'-end processing" "0000214=tRNA-intron endonuclease complex, 0005849=mRNA cleavage factor complex" "CG5970, cg5970" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR010655=Pre-mRNA cleavage complex subunit Clp1, IPR028606=Polyribonucleotide 5-hydroxyl-kinase Clp1" CG5970 16-Dec-15 2015_12 ENSDARG00000063663(LOC565621) YOR250C(CLP1) WBGene00010304(clpf-1) ENSXETG00000007088(TEgg012h01.1) ENSMUSG00000027079(Clp1) ENSG00000172409(CLP1) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0263487 scaRNA:ë¬U5-44 small Cajal body-specific RNA : ë¬U5-44 http://flybase.net/reports/FBgn0263487.html snoRNA_gene 0015030=Cajal body "snoRNA:tra2-a, pugU5-44" CR43602 16-Dec-15 2015_12 FBgn0026593 CG5707 http://flybase.net/reports/FBgn0026593.html FBgn0035314 protein_coding_gene "BEST:HL03644, HL03644" "IPR000073=Alpha/beta hydrolase fold-1, IPR029058=Alpha/Beta hydrolase fold" CG5707 16-Dec-15 2015_12 "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" "ENSG00000183569(SERHL2),ENSG00000172250" "viable,fertile" FBgn0065447 l(2)SH1406 lethal (2) SH1406 http://flybase.net/reports/FBgn0065447.html gene l(2)SH2 1406 16-Dec-15 2015_12 "lethal,recessive" FBgn0024220 ird8 immune response deficient 8 http://flybase.net/reports/FBgn0024220.html gene 0006963=positive regulation of antibacterial peptide biosynthetic process ird 16-Dec-15 2015_12 "viable,lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0039154 Npc2f Niemann-Pick type C-2f http://flybase.net/reports/FBgn0039154.html FBgn0064913 protein_coding_gene 0032934=sterol binding 0015918=sterol transport "CG6164, BcDNA:LP08842, npc2f" "IPR014756=Immunoglobulin E-set, IPR003172=MD-2-related lipid-recognition domain" CG6164 16-Dec-15 2015_12 "viable,fertile" FBgn0042104 CG18747 http://flybase.net/reports/FBgn0042104.html protein_coding_gene Q9I7L1_DROME "IPR011022=Arrestin C-terminal-like domain, IPR011021=Arrestin-like, N-terminal, IPR014756=Immunoglobulin E-set" CG18747 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" "ENSXETG00000013606(ARRDC2),ENSXETG00000018085(arrdc3),ENSXETG00000002108(ARRDC4),ENSXETG00000011050(TXNIP)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" "ENSG00000105643(ARRDC2),ENSG00000113369(ARRDC3),ENSG00000140450(ARRDC4),ENSG00000117289(TXNIP)" viable FBgn0010725 l(3)00714 lethal (3) 00714 http://flybase.net/reports/FBgn0010725.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0020618 Rack1 Receptor of activated protein kinase C 1 http://flybase.net/reports/FBgn0020618.html protein_coding_gene 0005080=protein kinase C binding "0016243=regulation of autophagic vacuole size, 0035220=wing disc development, 0044829=positive regulation by host of viral genome replication, 0042335=cuticle development, 0000398=mRNA splicing, via spliceosome, 0009267=cellular response to starvation, 0048477=oogenesis, 0046716=muscle cell cellular homeostasis, 0018991=oviposition, 0075522=IRES-dependent viral translational initiation, 0007626=locomotory behavior, 0045725=positive regulation of glycogen biosynthetic process" "0071011=precatalytic spliceosome, 0005776=autophagic vacuole, 0005829=cytosol, 0005737=cytoplasm, 0005875=microtubule associated complex, 0071013=catalytic step 2 spliceosome" "i173, CG7111, Receptor for Activated C Kinase 1, RACK1, receptor for activated protein kinase C1, Guanine nucleotide-binding protein beta-subunit like protein, rack1, dRack1" "IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG7111 16-Dec-15 2015_12 ENSDARG00000041619(gnb2l1) YMR116C(ASC1) WBGene00010556(rack-1) ENSXETG00000024447(gnb2l1) ENSMUSG00000020372(Gnb2l1) ENSG00000204628(GNB2L1) "sterile,lethal - all die before end of larval stage,some die during larval stage,recessive,viable,visible,lethal,germline clone" "wing,cuticle,ovary,female germline stem cell,egg,trichogen cell,egg chamber,ring canal,germline clone,embryonic/larval fat body,glycogen granule,autophagic vacuole,embryonic/larval fat body | larval stage,autophagic vacuoleFRT.RnorCD2.Act5C,glycogen granuleFRT.RnorCD2.Act5C" DRSC23796 IK 0.401673533 2.122076413 0.301394475 -0.388200723 -0.941632822 2.548208513 FBgn0038407 CG6126 http://flybase.net/reports/FBgn0038407.html protein_coding_gene 0015101=organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CT19169 "IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain" CG6126 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "viable,fertile" DRSC15971 K -0.424372815 0.135434695 -0.221225313 0.518501601 1.015269836 1.854469737 FBgn0003434 slw slope wing http://flybase.net/reports/FBgn0003434.html gene 16-Dec-15 2015_12 "fertile,viable,visible,recessive" wing FBgn0050183 CG30183 http://flybase.net/reports/FBgn0050183.html "FBgn0034891, FBgn0034892" protein_coding_gene "CG4530, CG4093" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG30183 16-Dec-15 2015_12 viable DRSC04472 K 0.178345619 0.125936328 0.136915914 0.584630082 2.112812131 0.743870314 FBgn0058356 CG40356 http://flybase.net/reports/FBgn0058356.html protein_coding_gene 16-Dec-15 2015_12 FBgn0259306 C242 http://flybase.net/reports/FBgn0259306.html gene 16-Dec-15 2015_12 visible "wing,chaeta" FBgn0264744 CG44002 http://flybase.net/reports/FBgn0264744.html "FBgn0085435, FBgn0031510" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0003677=DNA binding" 0005634=nucleus "CG34406-2, CG34406, CG18555" "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG44002 16-Dec-15 2015_12 viable FBgn0010660 Nup214 Nucleoporin 214kD http://flybase.net/reports/FBgn0010660.html FBgn0034798 protein_coding_gene 0005515=protein binding "0090204=protein localization to nuclear pore, 0000059=protein import into nucleus, docking, 0046826=negative regulation of protein export from nucleus, 0007184=SMAD protein import into nucleus" "0005875=microtubule associated complex, 0005643=nuclear pore" "nup214, CAN/Nup214, CAN, CG3820, DCAN, Nup 214, dCAN, NUP214, Nup214, Nup, DNup214, l(2)10444, Nucleoporin 214" IPR015943=WD40/YVTN repeat-like-containing domain CG3820 16-Dec-15 2015_12 ENSDARG00000016212 WBGene00003800(npp-14) ENSXETG00000001475(NUP214) ENSMUSG00000001855(Nup214) ENSG00000126883(NUP214) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,cell growth defective" DRSC04421 K -0.47133738 0.850111723 0.055715324 0.325548257 1.741295498 -0.728281174 FBgn0015697 E(cactE10)81 "Enhancer of cactusE10, number 81" http://flybase.net/reports/FBgn0015697.html gene unnamed 16-Dec-15 2015_12 FBgn0036030 CG6767 http://flybase.net/reports/FBgn0036030.html protein_coding_gene "0004749=ribose phosphate diphosphokinase activity, 0000287=magnesium ion binding" "0007476=imaginal disc-derived wing morphogenesis, 0009165=nucleotide biosynthetic process, 0009156=ribonucleoside monophosphate biosynthetic process" "IPR029099=Ribose-phosphate pyrophosphokinase, N-terminal domain, IPR029057=Phosphoribosyltransferase-like, IPR000842=Phosphoribosyl pyrophosphate synthetase, conserved site, IPR005946=Ribose-phosphate diphosphokinase" CG6767 16-Dec-15 2015_12 "ENSDARG00000037506(prps1b),ENSDARG00000015524(prps1a)" "YBL068W(PRS4),YER099C(PRS2)" WBGene00020107(R151.2) ENSXETG00000014636(prps1) "ENSMUSG00000031432(Prps1),ENSMUSG00000079104(Gm5081),ENSMUSG00000025742(Prps2)" "ENSG00000147224(PRPS1),ENSG00000101911(PRPS2)" "viable,visible" trichogen cell DRSC08994 E -0.081210179 -0.074642132 -0.754761928 1.866865352 -0.850509604 0.86300685 FBgn0003352 seg short egg http://flybase.net/reports/FBgn0003352.html gene 0048477=oogenesis l(1)SE 16-Dec-15 2015_12 visible egg FBgn0001435 l(1)7Bc lethal (1) 7Bc http://flybase.net/reports/FBgn0001435.html gene 16-Dec-15 2015_12 "lethal,recessive,polyphasic,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011828 Pxn Peroxidasin http://flybase.net/reports/FBgn0011828.html protein_coding_gene "0020037=heme binding, 0004601=peroxidase activity" "0055114=oxidation-reduction process, 0006909=phagocytosis, 0006979=response to oxidative stress, 0030198=extracellular matrix organization" 0005578=proteinaceous extracellular matrix "Protein X, CG12002, peroxydasin, Dpxn, peroxidasin, CT1239, pxn, DmPxd-a" "IPR003591=Leucine-rich repeat, typical subtype, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR010255=Haem peroxidase, IPR001611=Leucine-rich repeat, IPR000372=Leucine-rich repeat N-terminal domain, IPR019791=Haem peroxidase, animal, IPR001007=VWFC domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG12002 16-Dec-15 2015_12 "WBGene00004256(pxn-1),WBGene00004257(pxn-2)" ENSMUSG00000020674(Pxdn) ENSG00000130508(PXDN) " larval stage , embryonic stage " " gastric caecum

, embryonic/larval fat body

, hemocyte

" embryonic stage " organism

, hemocyte

" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266454 CG45079 http://flybase.net/reports/FBgn0266454.html protein_coding_gene CG45079 16-Dec-15 2015_12 FBgn0022667 Dep2 Dep2 http://flybase.net/reports/FBgn0022667.html gene 0003677=DNA binding 0005634=nucleus DEP2 16-Dec-15 2015_12 FBgn0259854 Su(Ste):CR42423 Su(Ste):CR42423 http://flybase.net/reports/FBgn0259854.html non_protein_coding_gene CR42423 CR42423 16-Dec-15 2015_12 FBgn0263743 CG43668 http://flybase.net/reports/FBgn0263743.html FBgn0034550 protein_coding_gene 0016020=membrane CG15226 IPR002000=Lysosome-associated membrane glycoprotein CG43668 16-Dec-15 2015_12 FBgn0005752 l(1)TK307 lethal (1) TK307 http://flybase.net/reports/FBgn0005752.html gene l307 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0036707 CG13724 http://flybase.net/reports/FBgn0036707.html protein_coding_gene CG13724 16-Dec-15 2015_12 viable DRSC10053 E -1.455881331 0.426437307 2.806769261 -0.406840833 1.472298735 1.192553512 FBgn0028525 c(2)M crossover suppressor on 2 of Manheim http://flybase.net/reports/FBgn0028525.html protein_coding_gene "0007126=meiotic nuclear division, 0000712=resolution of meiotic recombination intermediates, 0007131=reciprocal meiotic recombination" "0008278=cohesin complex, 0000795=synaptonemal complex" "MEI-910, c(2)m, alpha-kleisin, CG4249, DS02740.10, C(2)M, BG:DS02740.10, mei-910" "IPR006910=Rad21/Rec8-like protein, N-terminal" CG4249 16-Dec-15 2015_12 adult stage | female && oogenesis stage | stage S1-7 presumptive oocyte && oocyte

"meiotic cell cycle defective,female fertile,viable,female,germline clone" FBgn0028260 l(3)66Ea lethal (3) 66Ea http://flybase.net/reports/FBgn0028260.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0260220 KG01932 http://flybase.net/reports/FBgn0260220.html gene 16-Dec-15 2015_12 visible "sex comb,sex comb tooth" FBgn0039029 CG4704 http://flybase.net/reports/FBgn0039029.html protein_coding_gene 0005509=calcium ion binding "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG4704 16-Dec-15 2015_12 viable FBgn0085518 CG40794 http://flybase.net/reports/FBgn0085518.html FBan0040794 protein_coding_gene 16-Dec-15 2015_12 FBgn0250895 zaa36f12 http://flybase.net/reports/FBgn0250895.html gene zaa36f12y1 16-Dec-15 2015_12 FBgn0038906 CG13416 http://flybase.net/reports/FBgn0038906.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005264 l(3)SG84 lethal (3) SG84 http://flybase.net/reports/FBgn0005264.html gene l(3)2614 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0032269 w-cup world cup http://flybase.net/reports/FBgn0032269.html FBgn0063696 protein_coding_gene 0007140=male meiosis "CG7363, world-cup, BcDNA:AT31112" CG7363 16-Dec-15 2015_12 viable FBgn0026738 CG7857 http://flybase.net/reports/FBgn0026738.html protein_coding_gene 0004843=ubiquitin-specific protease activity 0016579=protein deubiquitination "Q9VUN9, anon-Becker1" IPR003323=OTU domain CG7857 16-Dec-15 2015_12 ENSDARG00000022675(otud6b) YHL013C(OTU2) WBGene00009007(F21D5.2) ENSXETG00000014596(BC087978.1) "ENSMUSG00000040550(Otud6b),ENSMUSG00000051582(Otud6a)" "ENSG00000155100(OTUD6B),ENSG00000189401(OTUD6A)" "viable,fertile" FBgn0085712 CG41588 http://flybase.net/reports/FBgn0085712.html FBan0041588 protein_coding_gene 16-Dec-15 2015_12 FBgn0045059 fs(1)140 female sterile (1) 140 http://flybase.net/reports/FBgn0045059.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "nurse cell & actin filament,nurse cell & nucleus" FBgn0014174 fs(?)A253.1M3 fs(?)A253.1M3 http://flybase.net/reports/FBgn0014174.html gene unnamed 16-Dec-15 2015_12 "lethal,cold sensitive,female sterile" FBgn0031784 CG9222 http://flybase.net/reports/FBgn0031784.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0048812=neuron projection morphogenesis, 0006468=protein phosphorylation" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG9222 16-Dec-15 2015_12 "ENSG00000212122(TSSK1B),ENSG00000206203(TSSK2)" viable FBgn0004931 a(1)HM26 abnormal abdomen HM26 http://flybase.net/reports/FBgn0004931.html gene l(1)HM26 16-Dec-15 2015_12 "visible,recessive,cold sensitive" "tergite,sternite" FBgn0026351 Su(SuRaf1)IV Su(SuRaf1)IV http://flybase.net/reports/FBgn0026351.html gene Su[Su(Raf)1]IV 16-Dec-15 2015_12 "lethal,recessive" FBgn0260857 Bet1 BET1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0260857.html "FBgn0036855, FBgn0062942, FBgn0045028" protein_coding_gene "0005484=SNAP receptor activity, 0019905=syntaxin binding" "0016192=vesicle-mediated transport, 0022008=neurogenesis, 0006888=ER to Golgi vesicle-mediated transport" 0031201=SNARE complex "G14084, BET1, BcDNA:RH40423, CG14084, bs16e01.y1, Bet1, Dm Bet1" IPR000727=Target SNARE coiled-coil homology domain CG14084 16-Dec-15 2015_12 ENSDARG00000034885(bet1) WBGene00043064(nbet-1) ENSXETG00000027380(bet1) ENSMUSG00000032757(Bet1) ENSG00000105829(BET1) FBgn0067757 l(1)G0068 lethal (1) G0068 http://flybase.net/reports/FBgn0067757.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0052572 CG32572 http://flybase.net/reports/FBgn0052572.html "FBgn0030783, FBgn0030784" protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior, 0016319=mushroom body development" "CG13006, CG13007" CG32572 16-Dec-15 2015_12 "behavior defective,recessive,viable" "mushroom body alpha-lobe,mushroom body beta-lobe,adult mushroom body alpha'-lobe,adult mushroom body beta'-lobe" FBgn0060735 l(3)S067111b lethal (3) S067111b http://flybase.net/reports/FBgn0060735.html gene 0671/11 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033347 CG8248 http://flybase.net/reports/FBgn0033347.html protein_coding_gene CG8248 16-Dec-15 2015_12 viable FBgn0011092 l(1)Q52 lethal (1) Q52 http://flybase.net/reports/FBgn0011092.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0038144 CG8870 http://flybase.net/reports/FBgn0038144.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP38 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG8870 16-Dec-15 2015_12 viable FBgn0000451 ect ectodermal http://flybase.net/reports/FBgn0000451.html "FBgn0010018, FBgn0036073, FBgn0036074" protein_coding_gene 0035295=tube development 0005634=nucleus "Ifl, Interferon-like protein, Difl, CG6611, DROECT, CG11965" CG6611 16-Dec-15 2015_12 "viable,visible,body color defective" mesothoracic tergum DRSC11343 I 0.372803533 1.64264382 1.157198897 0.428907946 1.197435646 0.768581437 FBgn0086401 BG02491 http://flybase.net/reports/FBgn0086401.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0037719 bocks bocksbeutel http://flybase.net/reports/FBgn0037719.html protein_coding_gene "0005635=nuclear envelope, 0016021=integral component of membrane, 0005654=nucleoplasm, 0005737=cytoplasm" "emerin, bocksbeutel, Bocksbeutel, CG9424, Bocks" "IPR011015=LEM/LEM-like domain, IPR003887=LEM domain" CG9424 16-Dec-15 2015_12 viable FBgn0065202 l(2)SH2292 lethal (2) SH2292 http://flybase.net/reports/FBgn0065202.html gene l(2)SH2 2292 16-Dec-15 2015_12 "lethal,recessive" FBgn0033848 CG13330 http://flybase.net/reports/FBgn0033848.html protein_coding_gene CG13330 16-Dec-15 2015_12 FBgn0014164 fez freeze http://flybase.net/reports/FBgn0014164.html gene 0008049=male courtship behavior 16-Dec-15 2015_12 "courtship behavior defective,male,recessive,visible,mating defective" "eye,tergite,male" FBgn0023072 l(1)1Aj lethal (1) 1Aj http://flybase.net/reports/FBgn0023072.html gene 1200C30b 16-Dec-15 2015_12 "lethal,recessive" FBgn0020362 anon-1C2 anon-1C2 http://flybase.net/reports/FBgn0020362.html gene "unnamed, 1C2" 16-Dec-15 2015_12 FBgn0036468 CG13461 http://flybase.net/reports/FBgn0036468.html protein_coding_gene CG13461 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0267927 CR46208 http://flybase.net/reports/FBgn0267927.html non_protein_coding_gene lincRNA.93 CR46208 16-Dec-15 2015_12 FBgn0016071 sog::Xlae\chordin sog::Xlae\chordin http://flybase.net/reports/FBgn0016071.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0065551 l(2)SH1035 lethal (2) SH1035 http://flybase.net/reports/FBgn0065551.html gene l(2)SH2 1035 16-Dec-15 2015_12 "lethal,recessive" FBgn0032815 CG10462 http://flybase.net/reports/FBgn0032815.html FBgn0062418 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" BcDNA:SD07008 "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG10462 16-Dec-15 2015_12 viable FBgn0264471 CR43879 http://flybase.net/reports/FBgn0264471.html non_protein_coding_gene CR43879 16-Dec-15 2015_12 FBgn0260936 scny scrawny http://flybase.net/reports/FBgn0260936.html "FBgn0035633, FBgn0062147, FBgn0010777" protein_coding_gene 0004843=ubiquitin-specific protease activity "1902459=positive regulation of stem cell maintenance, 0007591=molting cycle, chitin-based cuticle, 0045824=negative regulation of innate immune response, 0040007=growth, 0031937=positive regulation of chromatin silencing, 0042981=regulation of apoptotic process, 0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0035616=histone H2B conserved C-terminal lysine deubiquitination, 1900425=negative regulation of defense response to bacterium" "0005654=nucleoplasm, 0005730=nucleolus, 0005634=nucleus" "Q9VRP5, scrawny, Ubiquitin specific protease 36, scny, ubiquitin C-terminal hydrolase 36, et, emperor's thumb, Usp36, dUSP36, lethal (3) 02331, Ubiquitin-specific protease 36, ubiquitin-specific protease 36, mule, Scrawny, 2331, CG5505, USP36, dUsp36, Scny, anon-WO0118547.247, l(3)02331" "IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site" CG5505 16-Dec-15 2015_12 "ENSDARG00000032327(usp36),ENSDARG00000021448(eif2ak1)" "ENSMUSG00000051306(Usp42),ENSMUSG00000033909(Usp36)" "ENSG00000055483(USP36),ENSG00000106346(USP42)" pupal stage salivary gland

DRSC10509 IK -0.459841582 4.216582236 1.474476616 0.373148875 0.292412577 1.564232427 FBgn0024506 A359 A359 http://flybase.net/reports/FBgn0024506.html gene 16-Dec-15 2015_12 FBgn0016775 anon-73Bc anon-73Bc http://flybase.net/reports/FBgn0016775.html gene cDNA M 16-Dec-15 2015_12 FBgn0069194 l(2)hemo lethal (2) hemo http://flybase.net/reports/FBgn0069194.html gene 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" melanotic mass FBgn0065988 hrn heron http://flybase.net/reports/FBgn0065988.html gene "0016319=mushroom body development, 0048813=dendrite morphogenesis" 16-Dec-15 2015_12 "decreased cell number,somatic clone,neuroanatomy defective" "embryonic/larval mushroom body,somatic clone,adult mushroom body" FBgn0050506 tRNA:CR30506 transfer RNA:CR30506 http://flybase.net/reports/FBgn0050506.html "FBgn0011988, FBgn0050258, FBgn0060035" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033439=ACA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR30258, tRNA:thr3:47F, tRNA[Thr][[3]], AE002787.trna25-ThrTGT, CR30506, tRNA:T:TGT:AE002787-b, tRNA[[Thr]], tRNA:T3:47F, transfer RNA:thr3:47F, chr2R.trna84-ThrTGT" CR30506 16-Dec-15 2015_12 FBgn0036915 Prp3 Precursor RNA processing 3 http://flybase.net/reports/FBgn0036915.html protein_coding_gene 0044822=poly(A) RNA binding "0031935=regulation of chromatin silencing, 0000398=mRNA splicing, via spliceosome" "0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0046540=U4/U6 x U5 tri-snRNP complex, 0005687=U4 snRNP, 0005688=U6 snRNP" "dPrp3, PRPF3, Prp3, CG7757" "IPR013881=Pre-mRNA-splicing factor 3, IPR010541=Domain of unknown function DUF1115, IPR027104=U4/U6 small nuclear ribonucleoprotein Prp3" CG7757 16-Dec-15 2015_12 ENSDARG00000058430(prpf3) YDR473C(PRP3) WBGene00010844(M03C11.7) ENSXETG00000018654(prpf3) ENSMUSG00000015748(Prpf3) ENSG00000117360(PRPF3) "lethal - all die before end of P-stage,some die during P-stage,lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC10912 IE -0.930121959 2.676026069 -0.582410855 1.526208198 -1.216069414 -0.568723918 FBgn0022120 l(2)k06617 lethal (2) k06617 http://flybase.net/reports/FBgn0022120.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085300 Cpr65Ay Cuticular protein 65Ay http://flybase.net/reports/FBgn0085300.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG34271 "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG34271 16-Dec-15 2015_12 FBgn0015498 l(3)65CEb lethal (3) 65CEb http://flybase.net/reports/FBgn0015498.html gene "XI, Distal W5.4 Group XI" 16-Dec-15 2015_12 lethal FBgn0026641 l(2)k09015a lethal (2) k09015a http://flybase.net/reports/FBgn0026641.html gene l(2)k09015 16-Dec-15 2015_12 lethal "retina,somatic clone" FBgn0261243 Psa Puromycin sensitive aminopeptidase http://flybase.net/reports/FBgn0261243.html "FBgn0035226, FBgn0024513" protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "CG1009, dPSA, puromycin-sensitive-aminopeptidase, PSA, l(3)06226, dPsa, lethal (3) 06226, puromycin-sensitive aminopeptidase" "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain" CG1009 16-Dec-15 2015_12 ENSDARG00000044943 "YHR047C(AAP1),YKL157W(APE2)" WBGene00003914(pam-1) ENSXETG00000014725() ENSMUSG00000001441(Npepps) ENSG00000141279(NPEPPS) FBgn0065113 mok mimic of kojak http://flybase.net/reports/FBgn0065113.html gene 0048800=antennal morphogenesis 16-Dec-15 2015_12 FBgn0002203 l(3)67BDa lethal (3) 67BDa http://flybase.net/reports/FBgn0002203.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of larval stage,some die during larval stage" FBgn0030663 CG8117 http://flybase.net/reports/FBgn0030663.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "0006368=transcription elongation from RNA polymerase II promoter, 0022008=neurogenesis" 0005634=nucleus dCrsp70 "IPR017890=Transcription elongation factor S-IIM, IPR001222=Zinc finger, TFIIS-type, IPR003618=Transcription elongation factor S-II, central domain" CG8117 16-Dec-15 2015_12 YGL043W(DST1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0015927 demented demented http://flybase.net/reports/FBgn0015927.html gene 16-Dec-15 2015_12 FBgn0260575 MENE-DD3 http://flybase.net/reports/FBgn0260575.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0003936 snRNA:U5:35D small nuclear RNA U5 at 35EF http://flybase.net/reports/FBgn0003936.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "snRNA:U5, U5-35D, snRNA4, dU5, K2, snRNA:U5:35EF, U5snRNA, snRNA3, U5snRNA35EF, U5 snRNA 35D, U5 small nuclear RNA, U5 snRNA, U5, small nuclear RNA U5, U5:35D, CR32877, snRNA[[3]]" CR32877 16-Dec-15 2015_12 FBgn0065246 l(2)SH2138 lethal (2) SH2138 http://flybase.net/reports/FBgn0065246.html gene l(2)SH2 2138 16-Dec-15 2015_12 "lethal,recessive" FBgn0014235 l(2)31Er lethal (2) 31Er http://flybase.net/reports/FBgn0014235.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0024580 l(3)rM060 lethal (3) rM060 http://flybase.net/reports/FBgn0024580.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014154 e(S)X enhancer of S on X http://flybase.net/reports/FBgn0014154.html gene 16-Dec-15 2015_12 FBgn0058459 28SrRNA:CR40459 28SrRNA:CR40459 http://flybase.net/reports/FBgn0058459.html rRNA_gene CR40459 16-Dec-15 2015_12 FBgn0051249 CG31249 http://flybase.net/reports/FBgn0051249.html FBgn0038537 protein_coding_gene "CG7477, Q9VEG8" IPR019265=Protein of unknown function UPF0568 CG31249 16-Dec-15 2015_12 ENSDARG00000009253(zgc:56576) ENSXETG00000012195(C14orf166) ENSMUSG00000021807(2700060E02Rik) ENSG00000087302(C14orf166) "viable,fertile,body color defective" mesothoracic tergum FBgn0023164 Su(mg)1-3 Suppressor of modifier of gypsy 1-3 http://flybase.net/reports/FBgn0023164.html gene 16-Dec-15 2015_12 FBgn0001954 l(2)28Ac lethal (2) 28Ac http://flybase.net/reports/FBgn0001954.html gene "Complementation group L, L" 16-Dec-15 2015_12 lethal FBgn0019794 l(1)105 lethal (1) 105 http://flybase.net/reports/FBgn0019794.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052751 CG32751 http://flybase.net/reports/FBgn0052751.html FBgn0029847 protein_coding_gene "0016811=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" 0006807=nitrogen compound metabolic process "Pantetheine hydrolase, CG3648" "IPR012101=Biotinidase, eukaryotic, IPR003010=Carbon-nitrogen hydrolase" CG32751 16-Dec-15 2015_12 ENSDARG00000006926 "ENSXETG00000000104(BC087969.1),ENSXETG00000008991(BTD)" "ENSMUSG00000021900(Btd),ENSMUSG00000037440(Vnn1),ENSMUSG00000020010(Vnn3)" "ENSG00000169814(BTD),ENSG00000112299(VNN1),ENSG00000112303(VNN2),ENSG00000093134" FBgn0004232 l(3)93Bf lethal (3) 93Bf http://flybase.net/reports/FBgn0004232.html gene rlr4 16-Dec-15 2015_12 lethal FBgn0026370 SRPK SR Protein Kinase http://flybase.net/reports/FBgn0026370.html "FBgn0034015, FBgn0064783" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0018105=peptidyl-serine phosphorylation, 0006468=protein phosphorylation, 0007056=spindle assembly involved in female meiosis, 0030717=karyosome formation" "0005634=nucleus, 0005737=cytoplasm" "CG8174, dSRPK, srpk, BcDNA:SD03158, SRPK, cuaba, dSRPK1" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG8174 16-Dec-15 2015_12 "ENSDARG00000005916(LOC566605),ENSDARG00000000857(mapk14a),ENSDARG00000031560(srpk1b)" YMR216C(SKY1) WBGene00004980(spk-1) "ENSXETG00000000426(srpk1),ENSXETG00000000735(SRPK3),ENSXETG00000023173(SRPK2)" "ENSMUSG00000004865(Srpk1),ENSMUSG00000062604(Srpk2),ENSMUSG00000002007(Srpk3)" "ENSG00000096063(SRPK1),ENSG00000135250(SRPK2),ENSG00000184343(SRPK3)" "female sterile,viable,male sterile" "karyosome,meiotic spindleED2436),germline clone,chorion,chorion | germline clone,oocyte" FBgn0043841 vir-1 virus-induced RNA 1 http://flybase.net/reports/FBgn0043841.html "FBgn0032426, FBgn0032427, FBgn0051764" protein_coding_gene 0051607=defense response to virus "CG5453, Vir-1, virus-induced 1, Vir1, virus induced RNA-1, BEST:GH02216, vir-1, CG31764, vir1, CG15493, virus-induced RNA1" CG31764 16-Dec-15 2015_12 "viable,fertile" embryonic/larval salivary gland DRSC02863 EK -0.168889965 0.24012127 2.588054971 -1.972258025 -1.506284053 0.387521769 FBgn0262148 CR42874 http://flybase.net/reports/FBgn0262148.html non_protein_coding_gene CR42874 16-Dec-15 2015_12 FBgn0266652 CR45159 http://flybase.net/reports/FBgn0266652.html non_protein_coding_gene CR45159 16-Dec-15 2015_12 FBgn0020856 fs(2)261505 female sterile(2)261505 http://flybase.net/reports/FBgn0020856.html gene fs(2)B 16-Dec-15 2015_12 "female sterile,recessive" FBgn0005426 l(1)adl15 lethal (1) adl15 http://flybase.net/reports/FBgn0005426.html gene l(1)adl-15 16-Dec-15 2015_12 "lethal,heat sensitive,short lived,partially lethal - majority die" FBgn0035855 CG7366 http://flybase.net/reports/FBgn0035855.html FBgn0044691 protein_coding_gene anon-WO0140519.185 CG7366 16-Dec-15 2015_12 "viable,fertile" FBgn0036687 CG6652 http://flybase.net/reports/FBgn0036687.html protein_coding_gene 0006909=phagocytosis "IPR028933=Lebercilin domain, IPR026188=Lebercilin-like" CG6652 16-Dec-15 2015_12 ENSMUSG00000045275(Lca5l) viable FBgn0065224 l(2)SH2215 lethal (2) SH2215 http://flybase.net/reports/FBgn0065224.html gene l(2)SH2 2215 16-Dec-15 2015_12 "lethal,recessive" FBgn0034283 CG14492 http://flybase.net/reports/FBgn0034283.html protein_coding_gene "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG14492 16-Dec-15 2015_12 viable FBgn0043483 l(3)66EFc lethal (3) 66EFc http://flybase.net/reports/FBgn0043483.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043881 mecA mechanosensory A http://flybase.net/reports/FBgn0043881.html gene 0050954=sensory perception of mechanical stimulus 16-Dec-15 2015_12 FBgn0023001 melt melted http://flybase.net/reports/FBgn0023001.html FBgn0066864 protein_coding_gene "0010314=phosphatidylinositol-5-phosphate binding, 0035091=phosphatidylinositol binding" "0008286=insulin receptor signaling pathway, 0007422=peripheral nervous system development, 2001020=regulation of response to DNA damage stimulus, 0030730=sequestering of triglyceride, 0045464=R8 cell fate specification, 0001708=cell fate specification, 0007398=ectoderm development" 0005886=plasma membrane "anon-WO03014152.10, Melted, Q9VS24_DROME, 1441/14, Melt, CG8624, dMelt" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG8624 16-Dec-15 2015_12 ENSDARG00000031095(veph) WBGene00019615(K10B4.3) ENSXETG00000012240(VEPH1) ENSMUSG00000027831(Veph1) ENSG00000197415(VEPH1) "large body,small body,viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective" "wing,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval nervous system,photoreceptor cell R8 of pale ommatidium,supernumerary,photoreceptor cell R8 of yellow ommatidium" FBgn0085713 CG41589 http://flybase.net/reports/FBgn0085713.html FBan0041589 protein_coding_gene 16-Dec-15 2015_12 FBgn0032811 CG10268 http://flybase.net/reports/FBgn0032811.html FBgn0062883 protein_coding_gene 0004631=phosphomevalonate kinase activity "0008299=isoprenoid biosynthetic process, 0006695=cholesterol biosynthetic process" 0005777=peroxisome "BcDNA:SD12705, MevPK" "IPR005919=Higher eukaryotic phosphomevalonate kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10268 16-Dec-15 2015_12 ENSDARG00000070798(zgc:162701) WBGene00009335(F32D8.13) ENSMUSG00000027952(Pmvk) ENSG00000163344(PMVK) "partially lethal - majority die,some die during pupal stage" FBgn0036043 CG8177 http://flybase.net/reports/FBgn0036043.html "FBgn0027707, FBgn0064871" protein_coding_gene "0015301=anion:anion antiporter activity, 0005452=inorganic anion exchanger activity" 0006820=anion transport 0016021=integral component of membrane "BcDNA:RE59468, DAE, anon-EST:Posey259" "IPR003020=Bicarbonate transporter, eukaryotic, IPR013769=Band 3 cytoplasmic domain, IPR011531=Bicarbonate transporter, C-terminal, IPR016152=Phosphotransferase/anion transporter, IPR001717=Anion exchange protein" CG8177 16-Dec-15 2015_12 "ENSDARG00000028173(slc4a2a),ENSDARG00000052330(slc4a2b),ENSDARG00000053678" ENSXETG00000007160(SLC4A3) "ENSMUSG00000006576(Slc4a3),ENSMUSG00000028962(Slc4a2)" "ENSG00000114923(SLC4A3),ENSG00000164889(SLC4A2),ENSG00000004939(SLC4A1)" viable FBgn0262237 mir-2491 mir-2491 stem loop http://flybase.net/reports/FBgn0262237.html miRNA_gene "CR42944, dme-mir-2491" CR42944 16-Dec-15 2015_12 viable FBgn0035880 CG17352 http://flybase.net/reports/FBgn0035880.html protein_coding_gene CT33100 "IPR000859=CUB domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG17352 16-Dec-15 2015_12 viable FBgn0033598 Cpr47Eb Cuticular protein 47Eb http://flybase.net/reports/FBgn0033598.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG13224, DmelCpr47Eb" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG13224 16-Dec-15 2015_12 viable FBgn0010168 reticulated reticulated http://flybase.net/reports/FBgn0010168.html gene "Dret2, ret, dRet" 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced" "wing,wing vein,eye,postvertical bristle" FBgn0000012 abb abbreviated http://flybase.net/reports/FBgn0000012.html gene 16-Dec-15 2015_12 "visible,recessive" "macrochaeta,posterior scutellar bristle" FBgn0014964 gypsy\env gypsy\envelope http://flybase.net/reports/FBgn0014964.html transposable_element_gene "Gypsy Env, DmeGypV env, ENV, gypsy ENV-like ORF3, env, ORF3" IPR009882=Gypsy 16-Dec-15 2015_12 adult stage && oogenesis stage follicle cell

adult stage && oogenesis stage follicle cell

FBgn0051891 CG31891 http://flybase.net/reports/FBgn0051891.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002751 mit mitotic loss inducer http://flybase.net/reports/FBgn0002751.html gene 16-Dec-15 2015_12 "fertile,viable,mitotic cell cycle defective,maternal effect,recessive" FBgn0033774 CG12374 http://flybase.net/reports/FBgn0033774.html FBgn0044565 protein_coding_gene "0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" 0006508=proteolysis anon-WO0140519.63 "IPR009020=Proteinase inhibitor, propeptide, IPR000834=Peptidase M14, carboxypeptidase A, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide" CG12374 16-Dec-15 2015_12 ENSXETG00000008034() "ENSMUSG00000011463(Cpb1),ENSMUSG00000071553(Cpa2),ENSMUSG00000054446(Cpa1),ENSMUSG00000029788(Cpa5),ENSMUSG00000001865(Cpa3),ENSMUSG00000042501(Cpa6),ENSMUSG00000021999(Cpb2)" "ENSG00000158516(CPA2),ENSG00000091704(CPA1),ENSG00000158525(CPA5),ENSG00000153002(CPB1)" viable FBgn0033356 CG8229 http://flybase.net/reports/FBgn0033356.html FBgn0064765 protein_coding_gene 0032783=ELL-EAF complex Uspl1l CG8229 16-Dec-15 2015_12 "viable,fertile" FBgn0037472 CG10098 http://flybase.net/reports/FBgn0037472.html protein_coding_gene CG10098 16-Dec-15 2015_12 "ENSDARG00000016611,ENSDARG00000043497(si:ch211-184m19.2)" "ENSXETG00000008487(SCRN3),ENSXETG00000021947(SCRN2),ENSXETG00000012057(SCRN1)" "ENSMUSG00000008226(Scrn3),ENSMUSG00000020877(Scrn2),ENSMUSG00000019124(Scrn1)" "ENSG00000144306(SCRN3),ENSG00000141295(SCRN2),ENSG00000136193(SCRN1)" viable FBgn0267665 CR46003 http://flybase.net/reports/FBgn0267665.html non_protein_coding_gene Dm_3L:48631 CR46003 16-Dec-15 2015_12 FBgn0046679 anon-38C.1 anon-38C.1 http://flybase.net/reports/FBgn0046679.html gene 38C.1 16-Dec-15 2015_12 FBgn0005333 podG podoptera of Goldschmidt http://flybase.net/reports/FBgn0005333.html gene pod-G 16-Dec-15 2015_12 visible wing FBgn0050090 CG30090 http://flybase.net/reports/FBgn0050090.html "FBgn0034038, FBgn0064961" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP41, BcDNA:GH21666, CG8215" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG30090 16-Dec-15 2015_12 WBGene00006621(try-3) "viable,fertile" FBgn0260459 CG14106 http://flybase.net/reports/FBgn0260459.html FBgn0036358 protein_coding_gene "IPR027012=Enkurin domain, IPR027710=Enkurin domain-containing protein 1" CG14106 16-Dec-15 2015_12 viable FBgn0014064 Su(tor)3-293 Su(tor)3-293 http://flybase.net/reports/FBgn0014064.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028515 EndoGI Endonuclease G inhibitor http://flybase.net/reports/FBgn0028515.html FBgn0027856 protein_coding_gene "0016817=hydrolase activity, acting on acid anhydrides, 0008428=ribonuclease inhibitor activity, 0042162=telomeric DNA binding, 0003684=damaged DNA binding" "0045747=positive regulation of Notch signaling pathway, 0000723=telomere maintenance, 0060702=negative regulation of endoribonuclease activity, 0006310=DNA recombination, 0006303=double-strand break repair via nonhomologous end joining, 0008045=motor neuron axon guidance" "0043564=Ku70:Ku80 complex, 0005634=nucleus" "CG4930, dEndoGI, endoGI, BG:DS07473.2" "IPR014893=Ku, C-terminal, IPR024193=Ku80" CG4930 16-Dec-15 2015_12 "flight defective,visible,somatic clone,increased cell number,neuroanatomy defective,partially lethal - majority die,some die during third instar larval stage,uncoordinated,small body,lethal,recessive,male sterile,female fertile" "eye,somatic clone,wing disc,wing,posterior,wing vein,wing margin bristle,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,segmental nerve branch SNc of A1-7,intersegmental nerve,leg" FBgn0085470 lmgB lemming B http://flybase.net/reports/FBgn0085470.html "FBan0018042, FBgn0029004" protein_coding_gene "CG34441, ORF2, Dromel_CG18042_FBtr0079695_lmg_mORF" CG34441 16-Dec-15 2015_12 FBgn0023426 sauf sauf http://flybase.net/reports/FBgn0023426.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0065290 l(2)SH2013 lethal (2) SH2013 http://flybase.net/reports/FBgn0065290.html gene l(2)SH2 2013 16-Dec-15 2015_12 "lethal,recessive" FBgn0260257 GSd471 http://flybase.net/reports/FBgn0260257.html gene 16-Dec-15 2015_12 lethal FBgn0034375 CG12613 http://flybase.net/reports/FBgn0034375.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033763 CG8646 http://flybase.net/reports/FBgn0033763.html protein_coding_gene 0003943=N-acetylgalactosamine-4-sulfatase activity 0008152=metabolic process "IPR024607=Sulfatase, conserved site, IPR000917=Sulfatase, IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG8646 16-Dec-15 2015_12 ENSDARG00000063359(LOC563783) WBGene00006310(sul-3) "ENSXETG00000015525(ARSJ),ENSXETG00000000542(ARSB),ENSXETG00000011881(ARSI)" "ENSMUSG00000042082(Arsb),ENSMUSG00000036412(Arsi),ENSMUSG00000046561(Arsj)" "ENSG00000183876(ARSI),ENSG00000113273(ARSB),ENSG00000180801(ARSJ)" lethal FBgn0040182 l(1)G0279 lethal (1) G0279 http://flybase.net/reports/FBgn0040182.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002534 Lcp3 Larval cuticle protein 3 http://flybase.net/reports/FBgn0002534.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" "0008363=larval chitin-based cuticle development, 0040003=chitin-based cuticle development" 0031012=extracellular matrix "CG2043, Gene III, L[[3]]CP3, 3, CP3, LcpIII, cuticle p. III, DMLCP3, lcp3, LCP3, III, LCP-3, DmelLcp3" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG2043 16-Dec-15 2015_12 " larval stage | third instar stage 2 , larval stage | late third instar larval stage " " integumentary system

, organism

" "electrophoretic variant,viable" FBgn0262005 CG42823 http://flybase.net/reports/FBgn0262005.html "FBgn0054053, FBgn0082653" protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "BP1087, CG34053, HDC14119" IPR002350=Kazal domain CG42823 16-Dec-15 2015_12 FBgn0021916 l(2)k11328 lethal (2) k11328 http://flybase.net/reports/FBgn0021916.html gene l(2)113/28 16-Dec-15 2015_12 "lethal,recessive" FBgn0043578 PGRP-SB1 PGRP-SB1 http://flybase.net/reports/FBgn0043578.html FBgn0036658 protein_coding_gene "0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0008270=zinc ion binding" "0006955=immune response, 0009253=peptidoglycan catabolic process, 0006952=defense response" "0005887=integral component of plasma membrane, 0005576=extracellular region, 0005875=microtubule associated complex" "peptidoglycan receptor protein SB1, 142657_at, protein-like, PGRP-SB, PGRP SB1, peptidoglycan recognition, Peptidoglycan-recognition protein-SB1 precursor, CG9681, Peptidoglycan recognition protein SB1" "IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein, IPR017331=Peptidoglycan recognition protein, PGRP-S" CG9681 16-Dec-15 2015_12 "ENSDARG00000023215,ENSDARG00000068382(pglyrp5)" FBgn0000221 brn brainiac http://flybase.net/reports/FBgn0000221.html FBgn0005387 protein_coding_gene "0008378=galactosyltransferase activity, 0046981=beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity, 0008375=acetylglucosaminyltransferase activity" "0007298=border follicle cell migration, 0030707=ovarian follicle cell development, 0006486=protein glycosylation, 0001744=optic lobe placode formation, 0007293=germarium-derived egg chamber formation, 0016333=morphogenesis of follicular epithelium, 0048477=oogenesis, 0007299=ovarian follicle cell-cell adhesion, 0006688=glycosphingolipid biosynthetic process, 0042248=maintenance of polarity of follicular epithelium" "0016020=membrane, 0005576=extracellular region" "Brainiac, Brn, Gene B, CG4934, EG:EG0007.6, l(1)6P6, fs(1)A107, brc, fs(1)107" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR002659=Glycosyl transferase, family 31" CG4934 16-Dec-15 2015_12 "ENSDARG00000043482(zgc:86586),ENSDARG00000058066(LOC100002020),ENSDARG00000054373(LOC561028),ENSDARG00000058100(zgc:171538),ENSDARG00000053133(zgc:91787),ENSDARG00000038489(b3gnt7),ENSDARG00000041616(LOC798799),ENSDARG00000068219(si:dkey-224e22.3),ENSDARG00000052376(si:ch211-213b8.3),ENSDARG00000037611" WBGene00000270(bre-5) " adult stage && oogenesis stage , adult stage , oogenesis stage , embryonic stage " germarium | restricted

"lethal,rescuable maternal effect,cold sensitive,neurogenic phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,heat sensitive,neuroanatomy defective,female sterile,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "follicle cell,dorsal appendage,cold sensitive,germline cell,female,ovary,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina plexus" FBgn0260041 siren6 siren 6 http://flybase.net/reports/FBgn0260041.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0069415 JJF157 JJF157 http://flybase.net/reports/FBgn0069415.html gene 16-Dec-15 2015_12 stress response defective FBgn0037881 GCC88 GCC88 ortholog (H. sapiens) http://flybase.net/reports/FBgn0037881.html protein_coding_gene "0042803=protein homodimerization activity, 0030306=ADP-ribosylation factor binding, 0017137=Rab GTPase binding" "0048193=Golgi vesicle transport, 0000042=protein targeting to Golgi" "0000138=Golgi trans cisterna, 0005794=Golgi apparatus" "CG10703, GCC88, dGCC88" IPR000237=GRIP CG10703 16-Dec-15 2015_12 ENSDARG00000045541(gcc1) ENSXETG00000023063(GCC1) ENSMUSG00000029708(Gcc1) ENSG00000179562(GCC1) viable DRSC29299 K 0.380894362 0.101980666 0.292371011 0.106995776 -1.664256578 0.233616632 FBgn0040074 retinin retinin http://flybase.net/reports/FBgn0040074.html FBgn0036611 protein_coding_gene 0005615=extracellular space "Retinin, 4A11, CG13057" IPR007614=Retinin-like protein CG13057 16-Dec-15 2015_12 FBgn0065271 l(2)SH2057 lethal (2) SH2057 http://flybase.net/reports/FBgn0065271.html gene l(2)SH2 2057 16-Dec-15 2015_12 "lethal,recessive" FBgn0065624 l(2)SH0798 lethal (2) SH0798 http://flybase.net/reports/FBgn0065624.html gene l(2)SH2 0798 16-Dec-15 2015_12 "lethal,recessive" FBgn0035064 Aats-tyr-m mitochondrial tyrosyl-tRNA synthetase http://flybase.net/reports/FBgn0035064.html FBgn0025256 protein_coding_gene "0005524=ATP binding, 0003723=RNA binding, 0004831=tyrosine-tRNA ligase activity" 0070184=mitochondrial tyrosyl-tRNA aminoacylation 0005739=mitochondrion "anon-EST:fe1E12, anon-fast-evolving-1E12, Aatm, unnamed, CG16912" "IPR002305=Aminoacyl-tRNA synthetase, class Ic, IPR002307=Tyrosine-tRNA ligase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR002942=RNA-binding S4 domain, IPR024107=Tyrosine-tRNA ligase, bacterial-type, type 1, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR024088=Tyrosine-tRNA ligase, bacterial-type" CG16912 16-Dec-15 2015_12 ENSDARG00000054271(cdkn1b) YPL097W(MSY1) WBGene00006968(yars-1) ENSXETG00000012271(YARS2) ENSMUSG00000022792(Yars2) ENSG00000139131(YARS2) "viable,visible" trichogen cell FBgn0065171 l(3)SH023 lethal (3) SH023 http://flybase.net/reports/FBgn0065171.html gene l(2)SH3 023 16-Dec-15 2015_12 "lethal,recessive" FBgn0015906 atx abortex http://flybase.net/reports/FBgn0015906.html gene 16-Dec-15 2015_12 "lethal,recessive,rescuable maternal effect" "epidermis,ventral" FBgn0035316 CG15878 http://flybase.net/reports/FBgn0035316.html protein_coding_gene CG15878 16-Dec-15 2015_12 viable DRSC08486 K 0.272749717 0.133171915 0.672399514 -0.172274909 -0.185288507 1.67590223 FBgn0030005 CG2120 http://flybase.net/reports/FBgn0030005.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG2120 16-Dec-15 2015_12 viable FBgn0034011 CG8160 http://flybase.net/reports/FBgn0034011.html protein_coding_gene 0005576=extracellular region CG8160 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0038151 yellow-e2 yellow-e2 http://flybase.net/reports/FBgn0038151.html protein_coding_gene 0016853=isomerase activity 0042438=melanin biosynthetic process 0005576=extracellular region "CG17044, e2, Yellow-d3, yel-e2" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG17044 16-Dec-15 2015_12 FBgn0002493 l(3)SG53 lethal (3) SG53 http://flybase.net/reports/FBgn0002493.html gene l(3)1803 R16 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0051870 CG31870 http://flybase.net/reports/FBgn0051870.html "FBgn0045159, FBgn0045240, FBgn0062511" protein_coding_gene "bs19e04.y1, NEST:bs19e04, bs28a02.y1, NEST:bs28a02, BcDNA:AT11120" IPR010736=Sperm-tail PG-rich repeat CG31870 16-Dec-15 2015_12 FBgn0031201 CG12446 http://flybase.net/reports/FBgn0031201.html FBan0012446 protein_coding_gene IPR005240=Protein of unknown function DUF389 CG12446 16-Dec-15 2015_12 viable FBgn0040837 CG8620 http://flybase.net/reports/FBgn0040837.html protein_coding_gene CG8620 16-Dec-15 2015_12 FBgn0067785 anon-i232 anon-i232 http://flybase.net/reports/FBgn0067785.html gene "i232, XM080537.1" 16-Dec-15 2015_12 FBgn0063783 l(3)8B lethal (3) 8B http://flybase.net/reports/FBgn0063783.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0065789 l(2)SH0431 lethal (2) SH0431 http://flybase.net/reports/FBgn0065789.html gene l(2)SH2 0431 16-Dec-15 2015_12 "lethal,recessive" FBgn0037046 CG10581 http://flybase.net/reports/FBgn0037046.html protein_coding_gene "0098519=nucleotide phosphatase activity, acting on free nucleotides" 0007476=imaginal disc-derived wing morphogenesis "IPR003593=AAA+ ATPase domain, IPR004948=Nucleoside-triphosphatase, THEP1 type, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10581 16-Dec-15 2015_12 ENSDARG00000021853(zgc:92420) ENSXETG00000014584(C1orf57) ENSMUSG00000031851(2310079N02Rik) ENSG00000135778(NTPCR) viable FBgn0085254 CG34225 http://flybase.net/reports/FBgn0085254.html protein_coding_gene CG34225 16-Dec-15 2015_12 FBgn0002954 nofI no object fixation I http://flybase.net/reports/FBgn0002954.html gene 16-Dec-15 2015_12 "eye color defective,visual behavior defective" "rhabdomere | adult stage,pigment cell,optic lobe" FBgn0014051 Su(tor)2-280 Su(tor)2-280 http://flybase.net/reports/FBgn0014051.html gene 16-Dec-15 2015_12 FBgn0053357 5SrRNA:CR33357 5SrRNA:CR33357 http://flybase.net/reports/FBgn0053357.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33357 CR33357 16-Dec-15 2015_12 FBgn0082599 bek bek http://flybase.net/reports/FBgn0082599.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage" "metathoracic ventral denticle belt,germline clone,maternal effect,embryonic segment,stage 5 embryo" FBgn0051953 CR31953 http://flybase.net/reports/FBgn0051953.html FBgn0063614 pseudogene_attribute CG31953 CR31953 16-Dec-15 2015_12 FBgn0039054 Cow Carrier of Wingless http://flybase.net/reports/FBgn0039054.html protein_coding_gene "0017147=Wnt-protein binding, 0005509=calcium ion binding" "0030111=regulation of Wnt signaling pathway, 0035592=establishment of protein localization to extracellular region, 0006858=extracellular transport" "0005578=proteinaceous extracellular matrix, 0005615=extracellular space" "CG13830, carrier of Wingless, cow" "IPR011992=EF-hand domain pair, IPR019577=SPARC/Testican, calcium-binding domain, IPR000716=Thyroglobulin type-1, IPR002048=EF-hand domain, IPR002350=Kazal domain, IPR018247=EF-Hand 1, calcium-binding site" CG13830 16-Dec-15 2015_12 "ENSDARG00000070266(spock3),ENSDARG00000068968" ENSXETG00000006147(SPOCK2) "ENSMUSG00000056222(Spock1),ENSMUSG00000054162(Spock3),ENSMUSG00000058297(Spock2)" "ENSG00000196104(SPOCK3),ENSG00000152377(SPOCK1),ENSG00000107742(SPOCK2)" viable FBgn0023079 h::kni h::kni http://flybase.net/reports/FBgn0023079.html engineered_fusion_gene 16-Dec-15 2015_12 "viable,partially" FBgn0036646 CR18217 http://flybase.net/reports/FBgn0036646.html pseudogene_attribute CG18217 CR18217 16-Dec-15 2015_12 FBgn0031488 CG17265 http://flybase.net/reports/FBgn0031488.html protein_coding_gene 0016246=RNA interference "IPR019359=Protein of unknown function DUF2216, coiled-coil" CG17265 16-Dec-15 2015_12 "ENSDARG00000005232(ccdc85ca),ENSDARG00000039497(ccdc85a)" "ENSXETG00000025464(CCDC85C),ENSXETG00000006078(CCDC85A)" ENSG00000205476(CCDC85C) lethal FBgn0032313 CG14070 http://flybase.net/reports/FBgn0032313.html protein_coding_gene 0016021=integral component of membrane IPR002995=Surfeit locus 4 CG14070 16-Dec-15 2015_12 viable FBgn0259451 C325 http://flybase.net/reports/FBgn0259451.html gene 16-Dec-15 2015_12 visible wing FBgn0003413 siw side wings http://flybase.net/reports/FBgn0003413.html gene 16-Dec-15 2015_12 "viable,male,reduced,male sterile,recessive,visible" wing FBgn0004414 msopa male-specific opa containing gene http://flybase.net/reports/FBgn0004414.html FBgn0040640 protein_coding_gene "0006952=defense response, 0032504=multicellular organism reproduction" 0005615=extracellular space "Dromsopa, Drosophila male specific opa containing gene, CG14560" CG14560 16-Dec-15 2015_12 "viable,lethal" FBgn0267886 CR46174 http://flybase.net/reports/FBgn0267886.html pseudogene_attribute Mst35Ba-related CR46174 16-Dec-15 2015_12 FBgn0050177 CG30177 http://flybase.net/reports/FBgn0050177.html protein_coding_gene IPR004345=TB2/DP1/HVA22-related protein CG30177 16-Dec-15 2015_12 viable FBgn0262619 DNA-ligI DNA ligase I http://flybase.net/reports/FBgn0262619.html "FBgn0004596, FBgn0013774, FBgn0034922" protein_coding_gene "0005524=ATP binding, 0003910=DNA ligase (ATP) activity, 0003677=DNA binding" "0051103=DNA ligation involved in DNA repair, 0071897=DNA biosynthetic process, 0006310=DNA recombination" "0005737=cytoplasm, 0043596=nuclear replication fork" "CG5602, DmDNA Lig I, LIG1" "IPR016059=DNA ligase, ATP-dependent, conserved site, IPR012310=DNA ligase, ATP-dependent, central, IPR012309=DNA ligase, ATP-dependent, C-terminal, IPR012308=DNA ligase, ATP-dependent, N-terminal, IPR012340=Nucleic acid-binding, OB-fold, IPR000977=DNA ligase, ATP-dependent" CG5602 16-Dec-15 2015_12 ENSDARG00000060041(si:dkeyp-35b8.5) YDL164C(CDC9) WBGene00002985(lig-1) ENSXETG00000008805(LIG1) ENSMUSG00000056394(Lig1) ENSG00000105486(LIG1) embryonic stage | early-mid FBgn0058470 CG40470 http://flybase.net/reports/FBgn0058470.html FBan0040470 protein_coding_gene "0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR024571=ERAP1-like C-terminal domain" CG40470 16-Dec-15 2015_12 FBgn0065782 l(2)SH0441 lethal (2) SH0441 http://flybase.net/reports/FBgn0065782.html gene l(2)SH2 0441 16-Dec-15 2015_12 "lethal,recessive" FBgn0265164 CR44233 http://flybase.net/reports/FBgn0265164.html non_protein_coding_gene CR44233 16-Dec-15 2015_12 FBgn0086370 sra sarah http://flybase.net/reports/FBgn0086370.html "FBgn0020250, FBgn0010860, FBgn0026629, FBgn0046492, FBgn0061526" protein_coding_gene 0005515=protein binding "0030431=sleep, 0007616=long-term memory, 0007126=meiotic nuclear division, 0045924=regulation of female receptivity, 0046008=regulation of female receptivity, post-mating, 0007343=egg activation, 0007005=mitochondrion organization, 0070884=regulation of calcineurin-NFAT signaling cascade, 0035039=male pronucleus assembly, 0007127=meiosis I, 0008355=olfactory learning, 0007143=female meiotic division" "0005759=mitochondrial matrix, 0005634=nucleus, 0005737=cytoplasm" "anon-WO0118547.92, nebula, sara, Sra, CG6072, lethal (3) 05203, Sarah, anon-WO0172774.10, l(3)05203, 89B11, 89B, sarah, nla" IPR006931=Calcipressin CG6072 16-Dec-15 2015_12 "ENSDARG00000032623(rcan3),ENSDARG00000021869(zgc:85746),ENSDARG00000041157(rcan1),ENSDARG00000003109(zgc:100963)" WBGene00004321(rcn-1) "ENSXETG00000016260(dscr1l1),ENSXETG00000003636(BC074532.1)" "ENSMUSG00000039601(Rcan2),ENSMUSG00000059713(Rcan3),ENSMUSG00000022951(Rcan1)" "ENSG00000172348(RCAN2),ENSG00000117602(RCAN3),ENSG00000159200(RCAN1)" FBgn0021832 l(2)k15826 lethal (2) k15826 http://flybase.net/reports/FBgn0021832.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065826 l(2)SH0359 lethal (2) SH0359 http://flybase.net/reports/FBgn0065826.html gene l(2)SH2 0359 16-Dec-15 2015_12 "lethal,recessive" FBgn0033389 Rad51C Rad51C http://flybase.net/reports/FBgn0033389.html protein_coding_gene "0008094=DNA-dependent ATPase activity, 0000150=recombinase activity" "0006281=DNA repair, 0006310=DNA recombination" "dmRad51C, CG2412, Dm CG2412" "IPR013632=DNA recombination and repair protein Rad51, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG2412 16-Dec-15 2015_12 viable FBgn0033296 Mal-A7 Maltase A7 http://flybase.net/reports/FBgn0033296.html protein_coding_gene "0043169=cation binding, 0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process "CG11669, CT36683, mal_A7, Drome_A7" "IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR015902=Glycoside hydrolase, family 13, IPR013781=Glycoside hydrolase, catalytic domain" CG11669 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable FBgn0034755 CG3746 http://flybase.net/reports/FBgn0034755.html protein_coding_gene CG3746 16-Dec-15 2015_12 viable FBgn0036881 Cpr76Bd Cuticular protein 76Bd http://flybase.net/reports/FBgn0036881.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG9299, DmelCpr76Bd" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG9299 16-Dec-15 2015_12 "viable,visible" tergite FBgn0264367 CR43819 http://flybase.net/reports/FBgn0264367.html non_protein_coding_gene lincRNA.168 CR43819 16-Dec-15 2015_12 FBgn0020784 sDBP-X satellite DNA binding protein X http://flybase.net/reports/FBgn0020784.html gene 0003677=DNA binding pX 16-Dec-15 2015_12 FBgn0266885 CR45346 http://flybase.net/reports/FBgn0266885.html non_protein_coding_gene CR45346 16-Dec-15 2015_12 FBgn0266642 CR45149 http://flybase.net/reports/FBgn0266642.html non_protein_coding_gene CR45149 16-Dec-15 2015_12 FBgn0067363 l(2)NC45 lethal (2) NC45 http://flybase.net/reports/FBgn0067363.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065227 l(2)SH2207 lethal (2) SH2207 http://flybase.net/reports/FBgn0065227.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029990 CG2233 http://flybase.net/reports/FBgn0029990.html protein_coding_gene CG2233 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0003516 Stumpy Stumpy http://flybase.net/reports/FBgn0003516.html gene St 16-Dec-15 2015_12 "lethal,male" "wing,abdomen,eye,macrochaeta" FBgn0022175 l(2)k05419a lethal (2) k05419a http://flybase.net/reports/FBgn0022175.html gene l(2)k05419 16-Dec-15 2015_12 "lethal,recessive" FBgn0013514 l(1)14Af lethal (1) 14Af http://flybase.net/reports/FBgn0013514.html gene "l(1)13Fi, l(1)XIII, XIII" 16-Dec-15 2015_12 "lethal,recessive" FBgn0265637 CR44444 http://flybase.net/reports/FBgn0265637.html non_protein_coding_gene lincRNA.262 CR44444 16-Dec-15 2015_12 FBgn0032856 CG16798 http://flybase.net/reports/FBgn0032856.html protein_coding_gene 38C.41 CG16798 16-Dec-15 2015_12 viable FBgn0052564 CG32564 http://flybase.net/reports/FBgn0052564.html FBgn0030825 protein_coding_gene CG5095 CG32564 16-Dec-15 2015_12 "ENSXETG00000015080(),ENSXETG00000015480(),ENSXETG00000001378(),ENSXETG00000003613(),ENSXETG00000013355(),ENSXETG00000006375(),ENSXETG00000013595(),ENSXETG00000021278(),ENSXETG00000014082(),ENSXETG00000025634(),ENSXETG00000012800(),ENSXETG00000014412(),ENSXETG00000022340(),ENSXETG00000013141()" FBgn0013579 l(3)82Fg lethal (3) 82Fg http://flybase.net/reports/FBgn0013579.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0000328 clv-2 cloven thorax 2 http://flybase.net/reports/FBgn0000328.html gene "Clv, Cloven" 16-Dec-15 2015_12 "male sterile,recessive,visible,partially lethal - majority die,dominant" "adult thorax,wing,dorsal" FBgn0014296 l(3)64Bg lethal (3) 64Bg http://flybase.net/reports/FBgn0014296.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038463 CG3534 http://flybase.net/reports/FBgn0038463.html protein_coding_gene 0004856=xylulokinase activity "0046835=carbohydrate phosphorylation, 0005997=xylulose metabolic process" 0070062=extracellular exosome "IPR018485=Carbohydrate kinase, FGGY, C-terminal, IPR018484=Carbohydrate kinase, FGGY, N-terminal" CG3534 16-Dec-15 2015_12 ENSDARG00000043260(zgc:64119) YGR194C(XKS1) WBGene00011147(R08D7.7) ENSXETG00000012361() ENSMUSG00000035769(Xylb) ENSG00000093217(XYLB) viable FBgn0259708 CG42362 http://flybase.net/reports/FBgn0259708.html "FBgn0034648, FBan0015675" protein_coding_gene CG15675 CG42362 16-Dec-15 2015_12 FBgn0042150 CG18827 http://flybase.net/reports/FBgn0042150.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083010 snoRNA:ë¬28S-1135c snoRNA:ë¬28S-1135c http://flybase.net/reports/FBgn0083010.html snoRNA_gene "CR34604, Psi28S-1135c, psi28S-1135c" CR34604 16-Dec-15 2015_12 FBgn0014464 Cp7Fa Chorion protein a at 7F http://flybase.net/reports/FBgn0014464.html "FBgn0030042, FBgn0030043, FBgn0053962, FBtr0071199, FBpp0071146, FBtr0071200, FBpp0071147" protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion "A, CG15348, CG33962, CG15349" CG33962 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage S10B-13 , oogenesis stage | stage S12-13 " follicle cell

"visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0067090 I10 I10 http://flybase.net/reports/FBgn0067090.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0037940 CG14720 http://flybase.net/reports/FBgn0037940.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG14720 16-Dec-15 2015_12 viable FBgn0037797 CG12420 http://flybase.net/reports/FBgn0037797.html protein_coding_gene CG12420 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0262851 CR43215 http://flybase.net/reports/FBgn0262851.html pseudogene_attribute "noncoding_23159, noncoding_23161" CR43215 16-Dec-15 2015_12 FBgn0028145 l(3)S045608 lethal (3) S045608 http://flybase.net/reports/FBgn0028145.html gene 0456/08 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0052448 CG32448 http://flybase.net/reports/FBgn0052448.html protein_coding_gene IPR026686=UPF0708 protein C6orf162 CG32448 16-Dec-15 2015_12 ENSDARG00000071040(zgc:112287) ENSXETG00000025086(TEgg033e03.1) ENSMUSG00000028295(1810030N24Rik) ENSG00000111850(C6orf162) "viable,fertile" DRSC22657 I 2.542714952 -0.263531391 1.199729296 0.103431017 0.083664237 0.023627844 FBgn0005065 fs(2)OW205 female sterile (2) OW205 http://flybase.net/reports/FBgn0005065.html gene 16-Dec-15 2015_12 FBgn0085209 CG34180 http://flybase.net/reports/FBgn0085209.html protein_coding_gene CG34180 16-Dec-15 2015_12 FBgn0033980 Cyp6a20 Cyp6a20 http://flybase.net/reports/FBgn0033980.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" "0002118=aggressive behavior, 0050829=defense response to Gram-negative bacterium, 0055114=oxidation-reduction process" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG10245, p450, 6a20" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG10245 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0261680 CG42727 http://flybase.net/reports/FBgn0261680.html "FBgn0051392, FBan0031392, FBgn0038322" protein_coding_gene "CG12258, CG31392" IPR029063=S-adenosyl-L-methionine-dependent methyltransferase CG42727 16-Dec-15 2015_12 FBgn0026306 anon-16Fc anon-16Fc http://flybase.net/reports/FBgn0026306.html gene HL-IV 16-Dec-15 2015_12 FBgn0052087 CG32087 http://flybase.net/reports/FBgn0052087.html FBgn0036200 protein_coding_gene CG7308 CG32087 16-Dec-15 2015_12 viable FBgn0004188 snRNA:U6:96Aa small nuclear RNA U6 at 96Aa http://flybase.net/reports/FBgn0004188.html "FBgn0003455, FBgn0003939, FBgn0003940, FBgn0051379" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005688=U6 snRNP "DU6-1, dU6, snRNA4, snRNA:U6, K1, small nuclear RNA U6, U6 RNA, snRNA[[4]], snRNA-b, U6, small nuclear RNA b, U6:96Aa, snRNA6, CR31379, U6snRNA96Aa, U6-1, U6-1 small nuclear RNA, U6snRNA, U6-96Aa, U6 snRNA" CR31379 16-Dec-15 2015_12 FBgn0063920 M(UAS-dsh)8-4 M(UAS-dsh)8-4 http://flybase.net/reports/FBgn0063920.html gene 0016055=Wnt signaling pathway UAS-dsh M[8-4] 16-Dec-15 2015_12 FBgn0020292 l(2)39DEp lethal (2) 39DEp http://flybase.net/reports/FBgn0020292.html gene I259 16-Dec-15 2015_12 lethal FBgn0014250 l(2)60Ac lethal (2) 60Ac http://flybase.net/reports/FBgn0014250.html gene 16-Dec-15 2015_12 lethal FBgn0016050 obx obelix http://flybase.net/reports/FBgn0016050.html gene 0007422=peripheral nervous system development 16-Dec-15 2015_12 "lethal,recessive,some die during immature adult stage" "presumptive embryonic/larval peripheral nervous system,neuron,fascicle" FBgn0060400 l(3)S131909b lethal (3) S131909b http://flybase.net/reports/FBgn0060400.html gene 1319/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0025608 Faf2 Fas-associated factor http://flybase.net/reports/FBgn0025608.html protein_coding_gene "Faf, UBX domain 8 like, GT#49, Faf2, CG10372, FFAF, Fly Fas-associated factor" "IPR012336=Thioredoxin-like fold, IPR001012=UBX domain, IPR029071=Ubiquitin-related domain, IPR006577=UAS" CG10372 16-Dec-15 2015_12 ENSDARG00000052374(zgc:194819) YDL091C(UBX3) ENSXETG00000010945(TNeu075m11.1) ENSMUSG00000025873(Faf2) ENSG00000113194(FAF2) "viable,fertile" FBgn0032972 CG10834 http://flybase.net/reports/FBgn0032972.html FBan0010834 protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex "IPR016561=Dynein light chain roadblock-type 1/2, IPR004942=Roadblock/LAMTOR2 domain" CG10834 16-Dec-15 2015_12 FBgn0013239 E(var)211 E(var)211 http://flybase.net/reports/FBgn0013239.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0044059 GTD74-295-1 GTD74-295-1 http://flybase.net/reports/FBgn0044059.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036951 CG7017 http://flybase.net/reports/FBgn0036951.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG7017 16-Dec-15 2015_12 viable FBgn0033726 Cpr49Ad Cuticular protein 49Ad http://flybase.net/reports/FBgn0033726.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG8836 "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG8836 16-Dec-15 2015_12 FBgn0037409 Osi24 Osiris 24 http://flybase.net/reports/FBgn0037409.html protein_coding_gene CG15589 CG15589 16-Dec-15 2015_12 viable FBgn0001014 fs(3)A5 female sterile (3) A5 http://flybase.net/reports/FBgn0001014.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0265708 CR44515 http://flybase.net/reports/FBgn0265708.html non_protein_coding_gene "lincRNA.440, incRNA.440" CR44515 16-Dec-15 2015_12 FBgn0028601 l(2)W6 lethal (2) W6 http://flybase.net/reports/FBgn0028601.html gene l(2R)W6 16-Dec-15 2015_12 "lethal,recessive" FBgn0034982 CG4065 http://flybase.net/reports/FBgn0034982.html FBgn0023100 protein_coding_gene 0005737=cytoplasm anon-EST:Nelson1 "IPR007244=NatC N(alpha)-terminal acetyltransferase, Mak10 subunit" CG4065 16-Dec-15 2015_12 ENSDARG00000012378 YEL053C(MAK10) WBGene00020719(T23B12.4) ENSMUSG00000021555(Naa35) ENSG00000135040(NAA35) viable FBgn0034877 levy levy http://flybase.net/reports/FBgn0034877.html FBgn0047055 protein_coding_gene "0004129=cytochrome-c oxidase activity, 0030234=enzyme regulator activity" "0006123=mitochondrial electron transport, cytochrome c to oxygen, 0008340=determination of adult lifespan" "0005811=lipid particle, 0005751=mitochondrial respiratory chain complex IV" "COXE, BcDNA:RH03295, Cytochrome c oxidase Polypeptide VIA, COXD, Cytochrome c oxidase VIa, VIa, Cytochrome c oxidase polypeptide VIa, CG17280, Cytochrome c oxidase subunit 6A, COX6A, Cytochrome c oxidase Polypeptide VIa" "IPR001349=Cytochrome c oxidase, subunit VIa" CG17280 16-Dec-15 2015_12 "ENSDARG00000022438(cox6a1),ENSDARG00000054588(zgc:103594)" YGL191W(COX13) WBGene00006519(tag-174) "ENSXETG00000012222(),ENSXETG00000027544(cox6a1)" "ENSMUSG00000041697(Cox6a1),ENSMUSG00000030785(Cox6a2)" "ENSG00000111775(COX6A1),ENSG00000156885(COX6A2)" "viable,paralytic,heat sensitive,short lived,bang sensitive,neuroanatomy defective" "adult brain,optic lobe" DRSC04289 E -0.683115008 -0.259176279 -1.584119705 -0.38076981 -0.025054032 -0.439776477 FBgn0061133 l(3)S001917 lethal (3) S001917 http://flybase.net/reports/FBgn0061133.html gene 0019/17 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0030440 CG15719 http://flybase.net/reports/FBgn0030440.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033180=proton-transporting V-type ATPase, V1 domain" "IPR008218=ATPase, V1 complex, subunit F, IPR005772=ATPase, V1 complex, subunit F, eukaryotic" CG15719 16-Dec-15 2015_12 FBgn0262806 CR43177 http://flybase.net/reports/FBgn0262806.html pseudogene_attribute CG43177 CR43177 16-Dec-15 2015_12 FBgn0000348 cop copper http://flybase.net/reports/FBgn0000348.html gene 16-Dec-15 2015_12 "eye color defective,recessive,visible,viable,fertile" "pigment cell,wing" FBgn0265271 CG14717 http://flybase.net/reports/FBgn0265271.html "FBgn0037938, FBgn0066872" protein_coding_gene 0052689=carboxylic ester hydrolase activity anon-SAGE:Wang-126 "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG14717 16-Dec-15 2015_12 FBgn0035099 CG6845 http://flybase.net/reports/FBgn0035099.html FBgn0046266 protein_coding_gene 0016021=integral component of membrane BEST:LD22345 IPR012858=Dendritic cell-specific transmembrane protein-like CG6845 16-Dec-15 2015_12 ENSDARG00000018957 WBGene00007117(spe-42) "ENSXETG00000005468(),ENSXETG00000003334()" ENSG00000163354(DCST2) FBgn0011050 l(1)Q3 lethal (1) Q3 http://flybase.net/reports/FBgn0011050.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0000546 EcR Ecdysone receptor http://flybase.net/reports/FBgn0000546.html "FBgn0011242, FBgn0021762, FBgn0033064, FBgn0062534" protein_coding_gene "0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0005515=protein binding, 0008270=zinc ion binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0046982=protein heterodimerization activity, 0070491=repressing transcription factor binding, 0005496=steroid binding, 0001225=RNA polymerase II transcription coactivator binding, 0001047=core promoter binding, 0000976=transcription regulatory region sequence-specific DNA binding, 0003677=DNA binding, 0004884=ecdysteroid hormone receptor activity" "0007443=Malpighian tubule morphogenesis, 0018990=ecdysis, chitin-based cuticle, 0007298=border follicle cell migration, 0043457=regulation of cellular respiration, 0043401=steroid hormone mediated signaling pathway, 0043065=positive regulation of apoptotic process, 0007476=imaginal disc-derived wing morphogenesis, 0048738=cardiac muscle tissue development, 0010002=cardioblast differentiation, 0007291=sperm individualization, 0035075=response to ecdysone, 0007155=cell adhesion, 0035180=larval wandering behavior, 0048813=dendrite morphogenesis, 0007488=histoblast morphogenesis, 0006914=autophagy, 0007422=peripheral nervous system development, 0035073=pupariation, 0007286=spermatid development, 0035076=ecdysone receptor-mediated signaling pathway, 0048666=neuron development, 0007552=metamorphosis, 0035188=hatching, 0016322=neuron remodeling, 0044130=negative regulation of growth of symbiont in host, 0008258=head involution, 0035053=dorsal vessel heart proper cell fate commitment, 0010506=regulation of autophagy, 0008362=chitin-based embryonic cuticle biosynthetic process, 0006357=regulation of transcription from RNA polymerase II promoter, 0006911=phagocytosis, engulfment, 0007616=long-term memory, 0007561=imaginal disc eversion, 0045892=negative regulation of transcription, DNA-templated, 0045938=positive regulation of circadian sleep/wake cycle, sleep, 0007517=muscle organ development, 0008544=epidermis development, 0045893=positive regulation of transcription, DNA-templated, 0035193=larval central nervous system remodeling, 0035297=regulation of Malpighian tubule diameter, 0007468=regulation of rhodopsin gene expression, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007406=negative regulation of neuroblast proliferation, 0008340=determination of adult lifespan, 0007281=germ cell development, 0035071=salivary gland cell autophagic cell death, 0048477=oogenesis, 0042220=response to cocaine, 0016319=mushroom body development, 0007390=germ-band shortening, 0040034=regulation of development, heterochronic, 0035206=regulation of hemocyte proliferation, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0030425=dendrite, 0008231=repressor ecdysone receptor complex, 0005700=polytene chromosome, 0008230=ecdysone receptor holocomplex, 0008232=activator ecdysone receptor complex, 0005737=cytoplasm, 0005634=nucleus" "DmEcR, ECR, EcR-B1, ecdysone receptor, Ecr, ecdysteroid receptor, ecdysterone receptor, EcR-A, CG8347, dmEcR, EcR-B, ECR-C, anon-WO0229075.1, CG1765, ecdysone receptor complex, EcRB-1, EcdR, Dhr23, Ecdyson Receptor 1b, EcRB, EcRC, long island expressway, Ecdysone Receptor, NR1H1, EcRB1, snt, ecr, lie, DEcR, snaggletooth, male sterile(2)42A, EcR1b, ms(2)42A, Ecr1B, dECR, ms(2)06410, EcRA" "IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR003069=Ecdysteroid receptor, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG1765 16-Dec-15 2015_12 WBGene00003638(nhr-48) " embryonic stage | late , larval stage | second instar , pupal stage | early , larval stage--adult stage , pupal stage | mid , embryonic stage | mid , embryonic stage | >=3 hr , larval stage | first instar , pupal stage , larval stage | late third instar larval stage , larval stage | third instar , embryonic stage | 0-3 hr " organism

" prepupal stage , adult stage && oogenesis stage , larval stage | first instar , larval stage | late third instar larval stage , pupal stage | >=12 hr , pupal stage , embryonic stage , adult stage , embryonic stage | early " " ventral thoracic disc

, follicle cell

, epidermis

, eye-antennal disc

, embryonic/larval trachea

, imaginal disc

, embryonic/larval midgut

, organism

, neuron | subset

, salivary gland imaginal ring

, histoblast nest

, foregut imaginal ring

, nurse cell

, ovary

, hindgut imaginal ring

, prothoracic gland

, Malpighian tubule

, ventral nervous system | restricted

, larval muscle system

, midgut imaginal island

, embryonic/larval salivary gland

, dorsal metathoracic disc

, labial disc

, embryonic/larval fat body

" "lethal,recessive,heat sensitive,sleep defective,dominant,long lived,male,RU486 conditional,short lived,female,neuroanatomy defective,visible,size defective,male sterile,partially lethal - majority die,partially,cell death defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,feeding behavior defective,locomotor behavior defective,female sterile,some die during pupal stage,some die during third instar larval stage,courtship behavior defective,conditional,memory defective,decreased cell death,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,male fertile,lethal - all die before end of pupal stage,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,small body,developmental rate defective,cell shape defective,decreased cell size,circadian rhythm defective" "germline cell,supernumerary,heat sensitive,female germline cell,somatic clone,photoreceptor,lobe system of adult mushroom body,mushroom body beta-lobe,eye,mushroom body gamma-lobe | adult stage,adult mushroom body,spermatid,spermatozoon,primary spermatocyte cyst,spermatid & nucleus,wing,wing vein,ectopic,wing vein L3,anterior crossvein,leg,fusome | heat sensitive,cephalopharyngeal skeleton,embryonic/larval cuticle,embryonic/larval posterior spiracle,ventral thoracic disc,gastric caecum,embryonic/larval salivary gland | embryonic stage,midgut imaginal island,pupa,embryonic/larval midgut,adult midgut,salivary gland,germ band,puparium,puparial operculum,head,mouth hooks,egg chamber,germline clone,stage S14 oocyte,follicle cell,midgut constriction,embryo,embryonic/larval tracheal system,pupal cuticle,anterior pupal spiracle,embryonic/larval salivary gland,nurse cell ring canal,neuron & ventral nerve cord,gamma-lobe & neuron,adult brain,larva,nurse cell & nucleus | conditional ts,tergite,peripodial epithelium,histoblast nest,embryonic head,labral segment,epipharyngeal sclerite,dorsal pouch,Tv neuron & axonFMRFa.PS,neurohemal organ,ommatidium,pigment cell,wing disc,synapseMhc.PW,mesothoracic ventral neurosecretory neuron & axonFMRFa.PS,metathoracic ventral thoracic neurosecretory neuron & axonFMRFa.PS,prothoracic ventral neurosecretory neuron & axonFMRFa.PS,motor neuron,prepupal cuticle,germarium cap cell,border follicle cell,dorsal appendage,egg operculum,chorion,maternal effect,posterior scutellar bristle,imaginal disc,polytene chromosome puffSgs3.PD,embryonic/larval salivary gland | third instar larval stage,embryonic/larval salivary gland | prepupal stage,embryonic/larval salivary gland | pupal stage,autophagic vacuoleLsp2.PH,embryonic/larval fat body,mushroom body | P-stage,glial cell & brain & pupa | conditional tsTab2-201Y,dorsal closure embryo,extended germ band embryo,embryonic/first instar larval cuticle,neuron & ventral nerve cordCrz.PC,embryonic/larval epidermis,pupal epidermis,dendritic arborizing neuron | P-stage,embryonic/larval Malpighian tubule | larval stage,embryonic/larval Malpighian tubule Type II cell,wing margin,wing hair,embryonic/larval neuromuscular junction | larval stage,transverse nerve,reticular neuropil associated glial cell,gamma Kenyon cell,synapsealrm.PD,lysosomeLsp2.PH,fat body,autolysosomeLsp2.PH,microtubule & dorsal multidendritic neuron ddaC | pupal stageppk.PG,dendrite109(2)80,dorsal multidendritic neuron ddaC,oocyte,neuroblast,larval neuromere,CSD interneuron,midgut,denticle belt,embryo | dorsal closure stage,embryo | embryonic stage 14,amnioserosa,polar follicle cell,Tv neuron & filopodiumFMRFa.PS" FBgn0038440 Gr89a Gustatory receptor 89a http://flybase.net/reports/FBgn0038440.html protein_coding_gene 0008527=taste receptor activity 0050912=detection of chemical stimulus involved in sensory perception of taste 0016021=integral component of membrane "Gr89a, CG14901, GR89a" IPR013604=7TM chemoreceptor CG14901 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0265157 CR44226 http://flybase.net/reports/FBgn0265157.html non_protein_coding_gene lincRNA.835 CR44226 16-Dec-15 2015_12 FBgn0053825 His1:CG33825 His1:CG33825 http://flybase.net/reports/FBgn0053825.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0005634=nucleus, 0000786=nucleosome" CG33825 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5, IPR005818=Linker histone H1/H5, domain H15" CG33825 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0001825 l(1)ts lethal (1) ts http://flybase.net/reports/FBgn0001825.html gene lethal (1) temperature sensitive 16-Dec-15 2015_12 "lethal,cold sensitive" FBgn0029751 CG17764 http://flybase.net/reports/FBgn0029751.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" "0030532=small nuclear ribonucleoprotein complex, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005688=U6 snRNP, 0071013=catalytic step 2 spliceosome" CG17764 16-Dec-15 2015_12 viable FBgn0002805 ms(1)19Fd male sterile (1) 19Fd http://flybase.net/reports/FBgn0002805.html gene 16-Dec-15 2015_12 male sterile FBgn0005435 l(1)v25 lethal (1) v25 http://flybase.net/reports/FBgn0005435.html gene l(1)25 16-Dec-15 2015_12 FBgn0025549 unc-119 unc-119 http://flybase.net/reports/FBgn0025549.html protein_coding_gene 0007399=nervous system development "anon-EST:Posey123, Unc-119, Unc119, dm unc-119, CG1659, DmUNC-119" "IPR014756=Immunoglobulin E-set, IPR008015=GMP phosphodiesterase, delta subunit" CG1659 16-Dec-15 2015_12 "ENSDARG00000009629(unc119.1),ENSDARG00000044362(unc119b),ENSDARG00000034453" WBGene00006843(unc-119) ENSXETG00000012243(UNC119B) ENSMUSG00000046562(Unc119b) "ENSG00000109103(UNC119),ENSG00000175970(UNC119B)" viable FBgn0028837 CSN6 COP9 signalosome subunit 6 http://flybase.net/reports/FBgn0028837.html protein_coding_gene "0008237=metallopeptidase activity, 0008270=zinc ion binding, 0046983=protein dimerization activity" "0050821=protein stabilization, 0046331=lateral inhibition, 0036099=female germ-line stem cell maintenance, 0007281=germ cell development, 0007095=mitotic G2 DNA damage checkpoint, 0048140=male germ-line cyst encapsulation, 0010388=cullin deneddylation" 0008180=COP9 signalosome "Dch6, COP9 complex homolog subunit 6, Drosophila COP9 signalosome homolog 6, CG6932, CH6, Q9VCY3, Csn6" "IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR024969=Rpn11/EIF3F, C-terminal" CG6932 16-Dec-15 2015_12 WBGene00000818(csn-6) ENSXETG00000009101(cops6) ENSMUSG00000019494(Cops6) ENSG00000168090(COPS6) "lethal,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,locomotor behavior defective,short lived" "embryonic/larval brain,chaeta,supernumerary,trichogen cell,mesothoracic tergum,scutellar bristle" DRSC16593 K -0.011801496 -0.535545111 0.164144701 1.168583481 3.257681893 2.858732957 FBgn0033527 CG11777 http://flybase.net/reports/FBgn0033527.html FBgn0062984 protein_coding_gene "0005515=protein binding, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding, 0000209=protein polyubiquitination" 0071013=catalytic step 2 spliceosome "BcDNA:RE61564, cg11777" "IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000=Cyclophilin-like domain" CG11777 16-Dec-15 2015_12 ENSDARG00000033370(zgc:86715) WBGene00000886(cyn-10) ENSXETG00000018176(ppil3) ENSMUSG00000026035(Ppil3) ENSG00000115934 FBgn0015399 kek1 kekkon-1 http://flybase.net/reports/FBgn0015399.html "FBgn0005766, FBgn0028957" protein_coding_gene "0005154=epidermal growth factor receptor binding, 0048019=receptor antagonist activity" "0022008=neurogenesis, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0007175=negative regulation of epidermal growth factor-activated receptor activity, 0048477=oogenesis, 0000281=mitotic cytokinesis" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "l(2)01433, uns, Kekkon, kek-1, NB1, Dmkek1, kekkonI, Kekkon 1, Kekkon1, CG12283, Kek, Kekkon-1, CT18186, kek, Kek-1, kekon, kekkon, Kekon-1, n(2)k07332, SD01674, kekkon1, Kek1, KEK1, unstrung, BEST:GM02380, GM02380" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR003591=Leucine-rich repeat, typical subtype, IPR007110=Immunoglobulin-like domain, IPR000483=Cysteine-rich flanking region, C-terminal, IPR001611=Leucine-rich repeat" CG12283 16-Dec-15 2015_12 "ENSDARG00000071230(sc:d0343),ENSDARG00000027602(zgc:63670)" ENSXETG00000017309(slitl2) ENSMUSG00000043110(Lrrn4) "ENSG00000139211(AMIGO2),ENSG00000181754(AMIGO1),ENSG00000176020(AMIGO3)" " adult stage | female , embryonic stage " " ovary

, antenno-maxillary complex

, central nervous system

, peripheral nervous system | restricted

" "visible,lethal,recessive,neuroanatomy defective,viable" "wing vein,ectopic,dorsal appendage,maternal effect,egg,chorion | dorsalCY2,eye,chorion,wing vein L4,embryo,photoreceptor cell,ommatidium,wing vein L5,posterior crossvein,border follicle cell,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0066125 E(sda)I E(sda)I http://flybase.net/reports/FBgn0066125.html gene Line I 16-Dec-15 2015_12 "lethal,recessive" FBgn0050072 Obp50c Odorant-binding protein 50c http://flybase.net/reports/FBgn0050072.html "FBtr0087553, FBpp0086681" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp50c, CG30072" IPR006170=Pheromone/general odorant binding protein CG30072 16-Dec-15 2015_12 viable FBgn0001523 l(1)11Db lethal (1) 11Db http://flybase.net/reports/FBgn0001523.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone" FBgn0043351 EP3390 EP3390 http://flybase.net/reports/FBgn0043351.html gene EP(3)3390 16-Dec-15 2015_12 FBgn0016637 E64 E64 http://flybase.net/reports/FBgn0016637.html gene 16-Dec-15 2015_12 "behavior defective,recessive" FBgn0023212 EloB Elongin B http://flybase.net/reports/FBgn0023212.html FBgn0038807 protein_coding_gene "0007474=imaginal disc-derived wing vein specification, 0007526=larval somatic muscle development" "0070449=elongin complex, 0005875=microtubule associated complex, 0008023=transcription elongation factor complex" "d-elongin B, Elongin-B, Elo-B, CG4204, elongin B, ElonginB" "IPR029071=Ubiquitin-related domain, IPR000626=Ubiquitin domain" CG4204 16-Dec-15 2015_12 ENSDARG00000037980(tceb2) WBGene00001235(elb-1) ENSXETG00000018362(TCEB2) "ENSMUSG00000055839(Tceb2),ENSMUSG00000057534" ENSG00000103363(TCEB2) "lethal - all die before end of second instar larval stage,visible,dominant,lethal,viable,partially lethal - majority die" "wing vein L5,trichogen cell" FBgn0043999 Su(rst)C451 Su(rst)C451 http://flybase.net/reports/FBgn0043999.html gene 0001745=compound eye morphogenesis C451 16-Dec-15 2015_12 viable FBgn0016783 anon-91Aa anon-91Aa http://flybase.net/reports/FBgn0016783.html gene 16-Dec-15 2015_12 FBgn0032488 CG16812 http://flybase.net/reports/FBgn0032488.html protein_coding_gene 0005634=nucleus "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG16812 16-Dec-15 2015_12 WBGene00010002(F53F8.5) ENSXETG00000016954(TGas092l21.1) ENSMUSG00000049643(2310022A10Rik) ENSG00000160392(C19orf47) viable FBgn0051323 CG31323 http://flybase.net/reports/FBgn0051323.html FBgn0039416 protein_coding_gene CG14558 CG31323 16-Dec-15 2015_12 WBGene00044176(C30G7.2) "viable,fertile" FBgn0043859 pf-7 pairing failure-7 http://flybase.net/reports/FBgn0043859.html gene 0007140=male meiosis "CG7, Complementation group 7" 16-Dec-15 2015_12 FBgn0030438 CG15721 http://flybase.net/reports/FBgn0030438.html protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion IPR002350=Kazal domain CG15721 16-Dec-15 2015_12 "viable,fertile" DRSC19688 K -0.55107081 0.446321077 0.560768003 0.011024459 1.772834023 1.159722573 FBgn0028467 CG11070 http://flybase.net/reports/FBgn0028467.html protein_coding_gene 0034450=ubiquitin-ubiquitin ligase activity "0016567=protein ubiquitination, 0006511=ubiquitin-dependent protein catabolic process" 0000151=ubiquitin ligase complex "E4 A, CG 11070, BcDNA:LD34475, AABU01002759.1, UBE4A, UFD2a" "IPR019474=Ubiquitin conjugation factor E4, core, IPR003613=U box domain, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG11070 16-Dec-15 2015_12 ENSDARG00000040571(ube4a) ENSXETG00000010112(UBE4A) ENSMUSG00000059890(Ube4a) ENSG00000110344(UBE4A) viable FBgn0264868 CR44059 http://flybase.net/reports/FBgn0264868.html non_protein_coding_gene lincRNA.34 CR44059 16-Dec-15 2015_12 FBgn0259415 EP-256 http://flybase.net/reports/FBgn0259415.html gene 16-Dec-15 2015_12 visible "wing vein,chaeta" FBgn0261396 Rpn3 Regulatory particle non-ATPase 3 http://flybase.net/reports/FBgn0261396.html "FBgn0000486, FBgn0261364" protein_coding_gene "0008270=zinc ion binding, 0030234=enzyme regulator activity" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0042176=regulation of protein catabolic process" "0005838=proteasome regulatory particle, 0000502=proteasome complex, 0008541=proteasome regulatory particle, lid subcomplex" "diphenol oxidase A2, l(2)37Bf[+], DoxA2, Dox, CG42641, DXA2_DROME, p58, RPN3, l(2)37Bf, Diphenol oxidase A2, S3, Diphenol oxidase-A2, Dox-A2, CG10484" "IPR011990=Tetratricopeptide-like helical domain, IPR013586=26S proteasome regulatory subunit, C-terminal, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR013143=PCI/PINT associated module, IPR000717=Proteasome component (PCI) domain" CG42641 16-Dec-15 2015_12 ENSDARG00000018124 YER021W(RPN3) WBGene00004460(rpn-3) ENSXETG00000018552(PSMD3) ENSMUSG00000017221(Psmd3) ENSG00000108344(PSMD3) DRSC03318 IEK -3.072967016 -2.161496591 -2.378906512 -1.502394518 0.545816097 -2.63213844 FBgn0058167 CG40167 http://flybase.net/reports/FBgn0058167.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034839 CG13540 http://flybase.net/reports/FBgn0034839.html protein_coding_gene CG13540 16-Dec-15 2015_12 viable FBgn0002397 l(3)96Fa lethal (3) 96Fa http://flybase.net/reports/FBgn0002397.html gene l(3)C1 16-Dec-15 2015_12 "lethal,recessive" FBgn0267767 CR46098 http://flybase.net/reports/FBgn0267767.html non_protein_coding_gene CR46098 16-Dec-15 2015_12 FBgn0050375 CG30375 http://flybase.net/reports/FBgn0050375.html FBgn0033281 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG2280, SP80" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR000859=CUB domain" CG30375 16-Dec-15 2015_12 "ENSDARG00000060754(LOC557248),ENSDARG00000061173(st14a),ENSDARG00000062758" ENSXETG00000017920(BC076994.1) "ENSMUSG00000031995(St14),ENSMUSG00000016942(Tmprss6),ENSMUSG00000033177(Tmprss7)" "ENSG00000149418(ST14),ENSG00000187045(TMPRSS6),ENSG00000176040(TMPRSS7)" viable FBgn0019629 C62 C62 http://flybase.net/reports/FBgn0019629.html gene 16-Dec-15 2015_12 viable "scutum,dorsocentral bristle,posterior postalar bristle,scutellar bristle,macrochaeta" FBgn0037121 Rpb8 Rpb8 http://flybase.net/reports/FBgn0037121.html protein_coding_gene "0007095=mitotic G2 DNA damage checkpoint, 0006366=transcription from RNA polymerase II promoter" "0005665=DNA-directed RNA polymerase II, core complex" "RPB8, CG11246" "IPR012340=Nucleic acid-binding, OB-fold, IPR005570=RNA polymerase, Rpb8" CG11246 16-Dec-15 2015_12 ENSDARG00000038505(LOC792188) YOR224C(RPB8) WBGene00017830(rpb-8) ENSXETG00000017291(POLR2H) ENSMUSG00000021018(Polr2h) ENSG00000163882(POLR2H) lethal DRSC11642 IEK -1.310579089 2.207122293 -0.995848603 -1.839451888 2.473319941 1.434588309 FBgn0002799 ms(1)14 male sterile (1) 14 http://flybase.net/reports/FBgn0002799.html gene 16-Dec-15 2015_12 "male sterile,female fertile,viable" spermatid FBgn0038540 CG14321 http://flybase.net/reports/FBgn0038540.html protein_coding_gene CG14321 16-Dec-15 2015_12 viable FBgn0038412 Zip89B Zinc/iron regulated transporter-related protein 89B http://flybase.net/reports/FBgn0038412.html protein_coding_gene 0046873=metal ion transmembrane transporter activity "0030001=metal ion transport, 0055085=transmembrane transport" 0016324=apical plasma membrane "Zinc-iron transporter, dZip3, cg6898, dZip89B, CG6898, Zinc/iron transporter-related protein 3, Zinc/iron regulated transporter-related protein 3, ZIP3, Zip3" IPR003689=Zinc/iron permease CG6898 16-Dec-15 2015_12 ENSDARG00000058257(slc39a1) "YLR130C(ZRT2),YGL255W(ZRT1)" "WBGene00018897(F55F8.9),WBGene00017936(F30B5.7),WBGene00014669(C06G8.3),WBGene00013207(Y54G9A.4)" "ENSXETG00000001746(SLC39A2),ENSXETG00000004651(slc39a1),ENSXETG00000019914(TEgg075o04.1),ENSXETG00000003715(SLC39A3)" "ENSMUSG00000052310(Slc39a1),ENSMUSG00000046822(Slc39a3),ENSMUSG00000072572(Slc39a2)" ENSG00000165794(SLC39A2) "viable,developmental rate defective" FBgn0262473 Tl Toll http://flybase.net/reports/FBgn0262473.html "FBgn0003717, FBgn0062707" protein_coding_gene "0070976=TIR domain binding, 0019955=cytokine binding, 0004888=transmembrane signaling receptor activity, 0005515=protein binding" "0007352=zygotic specification of dorsal/ventral axis, 0019732=antifungal humoral response, 0006952=defense response, 0007416=synapse assembly, 0009617=response to bacterium, 0000281=mitotic cytokinesis, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0050830=defense response to Gram-positive bacterium, 0009880=embryonic pattern specification, 0035007=regulation of melanization defense response, 0050832=defense response to fungus, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0030097=hemopoiesis, 0035172=hemocyte proliferation, 0006955=immune response, 0045087=innate immune response, 0007507=heart development, 0009620=response to fungus, 0016201=synaptic target inhibition, 0009950=dorsal/ventral axis specification, 0002229=defense response to oomycetes, 0008063=Toll signaling pathway, 0019730=antimicrobial humoral response, 0007165=signal transduction, 0006967=positive regulation of antifungal peptide biosynthetic process, 0045610=regulation of hemocyte differentiation" "0016021=integral component of membrane, 0005769=early endosome, 0043234=protein complex, 0005886=plasma membrane, 0009897=external side of plasma membrane, 0005887=integral component of plasma membrane, 0005737=cytoplasm" "TOL, Toll1, Fs(3)Tl, mel(3)10, toll receptor, EP(3)1051, CT17414, T1, Fs(1)Tl, EP1051, dToll, Toll, Protein toll precursor, Toll receptor, mat(3)9, mel(3)9, dToll1, Toll-1, toll, TL, toll-1, CG5490, tl" "IPR026906=Leucine rich repeat 5, IPR001611=Leucine-rich repeat, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR000372=Leucine-rich repeat N-terminal domain, IPR000483=Cysteine-rich flanking region, C-terminal, IPR003591=Leucine-rich repeat, typical subtype" CG5490 16-Dec-15 2015_12 "ENSDARG00000019742,ENSDARG00000022048(tlr4bb)" embryonic stage&&pupal stage " embryonic stage | syncytial blastoderm , embryonic stage | embryonic cycle < 13 , embryonic stage | embryonic cycle 14 " FBgn0051028 CG31028 http://flybase.net/reports/FBgn0051028.html FBgn0039750 protein_coding_gene 0046872=metal ion binding "0006801=superoxide metabolic process, 0055114=oxidation-reduction process" CG2176 "IPR001424=Superoxide dismutase, copper/zinc binding domain" CG31028 16-Dec-15 2015_12 viable FBgn0266358 CR45006 http://flybase.net/reports/FBgn0266358.html non_protein_coding_gene CR45006 16-Dec-15 2015_12 FBgn0011906 tRNA:L2:44EF transfer RNA:leu2:44EF http://flybase.net/reports/FBgn0011906.html "FBgn0050292, FBgn0060154" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033420=CUG codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:leu2:44EF, tRNA[LEU], AE002787.trna30-LeuCAG, tRNA:L:CAG:AE002787, CR30292, tRNA[Leu][[2]], chr2R.trna12-LeuCAG, tRNA[Leu]" CR30292 16-Dec-15 2015_12 FBgn0036525 CG13451 http://flybase.net/reports/FBgn0036525.html protein_coding_gene FBgn0036525 16-Dec-15 2015_12 FBgn0015908 bangdoo bangdoo http://flybase.net/reports/FBgn0015908.html gene 0003677=DNA binding 0005634=nucleus 16-Dec-15 2015_12 FBgn0067733 l(1)G0497 lethal (1) G0497 http://flybase.net/reports/FBgn0067733.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0010086 SteXh Stellate in X heterochromatin http://flybase.net/reports/FBgn0010086.html "FBgn0005668, FBgn0014123" repeat_region "Heterochromatic Moderately Repetitive element, anon-Xh1, Ste het, heterochromatic Ste, Ste2, heterochromatic Stellate, Stellate 1, Ste1, hetSte, Stellate, HMR, SCLR, heterochromatic moderate repeat, HMR-element, Ste, unnamed, Stellate 1; Stellate 2, hSte" 16-Dec-15 2015_12 FBgn0052772 CG32772 http://flybase.net/reports/FBgn0052772.html "FBgn0029734, FBgn0029735" protein_coding_gene "0046872=metal ion binding, 0003677=DNA binding, 0003676=nucleic acid binding" "CG6911, CG15469" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR017956=AT hook, DNA-binding motif, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG32772 16-Dec-15 2015_12 "YPR015C(),YPR013C()" WBGene00009448(zfp-2) viable FBgn0037055 CG10519 http://flybase.net/reports/FBgn0037055.html FBgn0062474 protein_coding_gene BcDNA:GM10489 16-Dec-15 2015_12 FBgn0065867 l(2)SH0263 lethal (2) SH0263 http://flybase.net/reports/FBgn0065867.html gene l(2)SH2 0263 16-Dec-15 2015_12 "lethal,recessive" FBgn0020599 anon-3Bc anon-3Bc http://flybase.net/reports/FBgn0020599.html gene "I, Coding Region I" 16-Dec-15 2015_12 FBgn0083035 snoRNA:ë¬18S-525d snoRNA:ë¬18S-525d http://flybase.net/reports/FBgn0083035.html snoRNA_gene "psi18S-525d, CR34575" CR34575 16-Dec-15 2015_12 FBgn0036773 CG13698 http://flybase.net/reports/FBgn0036773.html protein_coding_gene CG13698 16-Dec-15 2015_12 viable FBgn0060421 l(3)S128010b lethal (3) S128010b http://flybase.net/reports/FBgn0060421.html gene 1280/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0051464 CG31464 http://flybase.net/reports/FBgn0051464.html FBgn0037564 protein_coding_gene CG11673 CG31464 16-Dec-15 2015_12 FBgn0060863 l(3)S047331 lethal (3) S047331 http://flybase.net/reports/FBgn0060863.html gene 0473/31 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0032916 CG9257 http://flybase.net/reports/FBgn0032916.html protein_coding_gene 0012505=endomembrane system IPR021720=Malectin CG9257 16-Dec-15 2015_12 ENSDARG00000059630(mlec) WBGene00018423(F44E2.10) ENSXETG00000012272(MLEC) ENSMUSG00000048578(Mlec) ENSG00000110917(MLEC) viable FBgn0001090 bnb bangles and beads http://flybase.net/reports/FBgn0001090.html protein_coding_gene "0042063=gliogenesis, 0007275=multicellular organismal development" "GAP43, CG7088, Gap43, Bnb, Bangles and beads, Bangles-n-beads" CG7088 16-Dec-15 2015_12 embryonic stage " epidermis

, mesectoderm

, embryonic central nervous system

, subesophageal ganglion

, supraesophageal ganglion

, amnioserosa

, glial cell

" "lethal,heat sensitive" "embryonic epidermis,presumptive embryonic/larval central nervous system" FBgn0267012 CR45456 http://flybase.net/reports/FBgn0267012.html non_protein_coding_gene CR45456 16-Dec-15 2015_12 FBgn0013435 Cdc2rk Cdc2-related kinase http://flybase.net/reports/FBgn0013435.html protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0004693=cyclin-dependent protein serine/threonine kinase activity" "0006468=protein phosphorylation, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "cdc2-related-kinase, CG1362, Dcdrk, cdc2rk" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG1362 16-Dec-15 2015_12 ENSDARG00000059862 ENSXETG00000000185(cdk10) ENSMUSG00000033862(Cdk10) ENSG00000185324(CDK10) " embryonic stage , embryonic stage -- adult stage "

ubiquitous viable FBgn0000555 E(f) Enhancer of forked http://flybase.net/reports/FBgn0000555.html gene "If, Intensifier of forked, I-f" 16-Dec-15 2015_12 "visible,recessive,viable,reduced,fertile,poor" "macrochaeta,posterior scutellar bristle" FBgn0259956 Sfp24C1 Seminal fluid protein 24C1 http://flybase.net/reports/FBgn0259956.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0032504=multicellular organism reproduction 0005615=extracellular space "CG42466, Seminal fluid protein 24C1" IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42466 16-Dec-15 2015_12 FBgn0038700 CG3734 http://flybase.net/reports/FBgn0038700.html protein_coding_gene 0008236=serine-type peptidase activity 0006508=proteolysis "IPR029058=Alpha/Beta hydrolase fold, IPR008758=Peptidase S28" CG3734 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0263461 snoRNA:CG32479-a http://flybase.net/reports/FBgn0263461.html snoRNA_gene chr3L:874744..875006 CR43576 16-Dec-15 2015_12 FBgn0065821 l(2)SH0367 lethal (2) SH0367 http://flybase.net/reports/FBgn0065821.html gene l(2)SH2 0367 16-Dec-15 2015_12 "lethal,recessive" FBgn0060509 l(3)S104315 lethal (3) S104315 http://flybase.net/reports/FBgn0060509.html gene 1043/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0262035 CG42846 http://flybase.net/reports/FBgn0262035.html protein_coding_gene CG42846 16-Dec-15 2015_12 FBgn0019791 l(1)12 lethal (1) 12 http://flybase.net/reports/FBgn0019791.html gene tsl(1)12 16-Dec-15 2015_12 "male sterile,heat sensitive,lethal,male,recessive" primary gonial cell FBgn0031489 CG17224 http://flybase.net/reports/FBgn0031489.html protein_coding_gene 0004850=uridine phosphorylase activity "0009166=nucleotide catabolic process, 0009116=nucleoside metabolic process" 0005737=cytoplasm "IPR010059=Uridine phosphorylase, eukaryotic, IPR000845=Nucleoside phosphorylase domain, IPR018017=Nucleoside phosphorylase" CG17224 16-Dec-15 2015_12 viable FBgn0039269 veli veli http://flybase.net/reports/FBgn0039269.html FBgn0064161 protein_coding_gene "0008582=regulation of synaptic growth at neuromuscular junction, 0007163=establishment or maintenance of cell polarity, 0007298=border follicle cell migration" "0045211=postsynaptic membrane, 0035003=subapical complex" "DLin-7, d-Veli, Lin-7, lin7, dLin-7, CG7662, DLin7, Flin-7, dVeli, dLin7, Dveli, lin-7, Veli, D-veli" "IPR001478=PDZ domain, IPR004172=L27 domain, IPR014775=L27 domain, C-terminal" CG7662 16-Dec-15 2015_12 "ENSDARG00000027322(lin7c),ENSDARG00000013414(lin7a)" WBGene00002996(lin-7) "ENSXETG00000014525(LIN7A),ENSXETG00000000264(LIN7B)" "ENSMUSG00000027162(Lin7c),ENSMUSG00000003872(Lin7b),ENSMUSG00000019906(Lin7a)" "ENSG00000148943(LIN7C),ENSG00000104863(LIN7B),ENSG00000111052(LIN7A)" "viable,fertile,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "eye photoreceptor cell,neuromuscular junction,trichogen cell,border follicle cell,chaeta,supernumerary" FBgn0025790 TBPH TAR DNA-binding protein-43 homolog http://flybase.net/reports/FBgn0025790.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003697=single-stranded DNA binding, 1990605=GU repeat RNA binding" "0007528=neuromuscular junction development, 0007417=central nervous system development, 2000331=regulation of terminal button organization, 1900006=positive regulation of dendrite development, 0007274=neuromuscular synaptic transmission, 0008345=larval locomotory behavior, 0043524=negative regulation of neuron apoptotic process, 0033119=negative regulation of RNA splicing, 0007628=adult walking behavior, 0008582=regulation of synaptic growth at neuromuscular junction, 0070507=regulation of microtubule cytoskeleton organization, 0007416=synapse assembly, 0072553=terminal button organization, 0008344=adult locomotory behavior, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0048812=neuron projection morphogenesis, 0033143=regulation of intracellular steroid hormone receptor signaling pathway, 0007626=locomotory behavior" "0048471=perinuclear region of cytoplasm, 0031673=H zone, 0005634=nucleus" "tbph, dmTDP43, TDP43, dtar, CG10327, dTDP, Tar DNA binding protein homolog, TDP-43, dTDP-43, TBPH, TAR DNA binding protein" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG10327 16-Dec-15 2015_12 "ENSDARG00000040031(tardbp),ENSDARG00000004452(tardbpl)" WBGene00006514(tdp-1) ENSXETG00000006317(tardbp) ENSMUSG00000041459(Tardbp) ENSG00000120948(TARDBP) " pupal stage , embryonic stage " "locomotor behavior defective,neuroanatomy defective,partially lethal - majority die,some die during pharate adult stage,viable,learning defective,lethal,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,visible,increased cell death,fertile,recessive,short lived,lethal - all die before end of P-stage,some die during third instar larval stage,gravitaxis defective,jump response defective,neurophysiology defective,progressive" "NMJ bouton,lobe system of adult mushroom body,NMJ bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage,eye,embryonic/larval neuromuscular junction | larval stage,NMJ bouton | larval stage,synaptic vesicle | larval stageD42,motor neuron | larval stage,ommatidium,type I bouton,embryonic/larval neuromuscular junction,ring neuron,progressive,adult mushroom body,axoney-OK107" FBgn0065046 snoRNA:U3:9B snoRNA:U3:9B http://flybase.net/reports/FBgn0065046.html FBgn0053662 snoRNA_gene 0030556=rRNA modification guide activity 0005730=nucleolus "snoRNA U3, chrX:10193506..10193607, CR33662, Dm-830, U3 snoRNA, U3-snoRNA, 9B U3 snoRNA" CR33662 16-Dec-15 2015_12 FBgn0065313 l(2)SH1936 lethal (2) SH1936 http://flybase.net/reports/FBgn0065313.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0262768 Su(E1)-B http://flybase.net/reports/FBgn0262768.html gene 16-Dec-15 2015_12 FBgn0039816 CG11317 http://flybase.net/reports/FBgn0039816.html protein_coding_gene 0046872=metal ion binding 0022008=neurogenesis "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG11317 16-Dec-15 2015_12 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0035313 CG13810 http://flybase.net/reports/FBgn0035313.html protein_coding_gene CG13810 16-Dec-15 2015_12 FBgn0267940 CR46220 http://flybase.net/reports/FBgn0267940.html non_protein_coding_gene lincRNA.906 CR46220 16-Dec-15 2015_12 FBgn0001819 l(1)rr lethal (1) ring gland rudimentary http://flybase.net/reports/FBgn0001819.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" ring gland FBgn0260310 GSd459 http://flybase.net/reports/FBgn0260310.html gene 16-Dec-15 2015_12 lethal FBgn0038313 CG4338 http://flybase.net/reports/FBgn0038313.html protein_coding_gene "IPR022968=Ribosome biogenesis protein, IPR007209=RNase L inhibitor RLI, possible metal-binding domain, IPR007177=Domain of unknown function DUF367" CG4338 16-Dec-15 2015_12 ENSDARG00000038567(zgc:92086) YOR006C(TSR3) WBGene00018679(F52C12.2) ENSXETG00000021589(C16orf42) ENSMUSG00000015126(0610007P22Rik) ENSG00000007520(C16orf42) "viable,fertile" FBgn0004058 olfF olfactory F http://flybase.net/reports/FBgn0004058.html gene olfactory-F 16-Dec-15 2015_12 "smell perception defective,recessive" FBgn0022371 Pt-3 Larval protein-3 http://flybase.net/reports/FBgn0022371.html gene 16-Dec-15 2015_12 FBgn0010421 TfIIFë_ Transcription factor TFIIFë_ http://flybase.net/reports/FBgn0010421.html FBgn0011350 protein_coding_gene "0001096=TFIIF-class transcription factor binding, 0003824=catalytic activity, 0004003=ATP-dependent DNA helicase activity" "0060261=positive regulation of transcription initiation from RNA polymerase II promoter, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0005674=transcription factor TFIIF complex, 0005634=nucleus" "TFIIF small subunit, RAP30, T2FB_DROME, TfIIF, dTFIIF30, TFIIFbeta, l(3)j3C1, TFIIF, CG6538, TfIIFbeta, F[[S]], factor 5" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR003196=Transcription initiation factor IIF, beta subunit, IPR011039=Transcription Factor IIF, Rap30/Rap74, interaction" CG6538 16-Dec-15 2015_12 "ENSDARG00000069910(gtf2f2),ENSDARG00000069897,ENSDARG00000006816(gtf2f2b)" YGR005C(TFG2) WBGene00012694(Y39B6A.36) ENSMUSG00000067995(Gtf2f2) ENSG00000188342(GTF2F2) "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005486 l(1)ts1681 lethal (1) ts1681 http://flybase.net/reports/FBgn0005486.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0260759 CG42557 http://flybase.net/reports/FBgn0260759.html "FBgn0039725, FBan0007866" protein_coding_gene CG7866 IPR028039=Coiled-coil domain containing protein 32 CG42557 16-Dec-15 2015_12 FBgn0039811 CG15550 http://flybase.net/reports/FBgn0039811.html protein_coding_gene CG15550 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0002485 l(3)SG45 lethal (3) SG45 http://flybase.net/reports/FBgn0002485.html FBgn0004725 gene "l(3)dsl-5, l(3)dsl5, l(3)7m-68" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,mitotic cell cycle,cell cycle" FBgn0082810 Dmc dymeclin http://flybase.net/reports/FBgn0082810.html gene 0008589=regulation of smoothened signaling pathway dDMC 16-Dec-15 2015_12 FBgn0262830 LAS110 http://flybase.net/reports/FBgn0262830.html nuclear_gene 0060968=regulation of gene silencing 16-Dec-15 2015_12 "lethal,male limited" FBgn0029183 E(Khc)ek3 E(Khc)ek3 http://flybase.net/reports/FBgn0029183.html gene 16-Dec-15 2015_12 FBgn0067422 E(TS2)2 E(TS2)2 http://flybase.net/reports/FBgn0067422.html gene 16-Dec-15 2015_12 FBgn0044380 anon-AE002870.1 anon-AE002870.1 http://flybase.net/reports/FBgn0044380.html gene unnamed 16-Dec-15 2015_12 FBgn0261509 haf hattifattener http://flybase.net/reports/FBgn0261509.html "FBgn0260797, FBgn0031349" protein_coding_gene 0008045=motor neuron axon guidance "CT33985, tartan/capricious-like, CG14351" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG14351 16-Dec-15 2015_12 ENSXETG00000014298(LRCH3) FBgn0027580 PCB Pyruvate carboxylase http://flybase.net/reports/FBgn0027580.html FBgn0033455 protein_coding_gene "0005524=ATP binding, 0046872=metal ion binding, 0004075=biotin carboxylase activity, 0004736=pyruvate carboxylase activity, 0009374=biotin binding, 0003677=DNA binding" "0006094=gluconeogenesis, 0006090=pyruvate metabolic process" "0005759=mitochondrial matrix, 0005875=microtubule associated complex, 0005811=lipid particle, 0005739=mitochondrion" "Pyruvate carboxylase, GH06348, BcDNA:GH06348, CG1516, pyruvate carboxylase, pyruvate carboxykinase, PC, BcDNA, Q0E9E2_DROME" "IPR011761=ATP-grasp fold, IPR013785=Aldolase-type TIM barrel, IPR013816=ATP-grasp fold, subdomain 2, IPR000891=Pyruvate carboxyltransferase, IPR013815=ATP-grasp fold, subdomain 1, IPR016185=Pre-ATP-grasp domain, IPR011053=Single hybrid motif, IPR011054=Rudiment single hybrid motif, IPR005479=Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR009057=Homeodomain-like, IPR005930=Pyruvate carboxylase, IPR005481=Biotin carboxylase-like, N-terminal domain, IPR005482=Biotin carboxylase, C-terminal, IPR000089=Biotin/lipoyl attachment, IPR003379=Carboxylase, conserved domain, IPR001882=Biotin-binding site, IPR011764=Biotin carboxylation domain" CG1516 16-Dec-15 2015_12 "ENSDARG00000000972(zgc:123047),ENSDARG00000051939(pc)" "YGL062W(PYC1),YBR218C(PYC2)" WBGene00004258(pyc-1) ENSXETG00000008415(PC) ENSMUSG00000024892(Pcx) ENSG00000173599(PC) "partially lethal - majority die,some die during pupal stage" FBgn0002762 mit(1)12 mitotic 12 http://flybase.net/reports/FBgn0002762.html gene 0007067=mitotic nuclear division 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0262397 mir-2c mir-2c stem loop http://flybase.net/reports/FBgn0262397.html "FBgn0067339, FBgn0262229" miRNA_gene "0046716=muscle cell cellular homeostasis, 0060548=negative regulation of cell death, 0045947=negative regulation of translational initiation" "CR33560, miR-2c, dme-miR-2c, miR-2, mir-2c, CR42936, miR2, miR2c, dme-mir-2c" CR42936 16-Dec-15 2015_12 embryonic stage -- adult stage viable FBgn0039531 CG5611 http://flybase.net/reports/FBgn0039531.html protein_coding_gene "0008416=delta5-delta2,4-dienoyl-CoA isomerase activity" 0008152=metabolic process "IPR001753=Crotonase superfamily, IPR029045=ClpP/crotonase-like domain" CG5611 16-Dec-15 2015_12 ENSDARG00000038876(zgc:101569) WBGene00001152(ech-3) "ENSXETG00000024634(),ENSXETG00000024633()" DRSC15843 E 1.449253694 -0.802747175 1.734222086 1.050123633 -1.279591895 -0.70113598 FBgn0030291 CG1738 http://flybase.net/reports/FBgn0030291.html FBgn0063062 protein_coding_gene BcDNA:RE11532 IPR027973=Protein of unknown function DUF4602 CG1738 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0002158 l(2)pm lethal (2) polymorph http://flybase.net/reports/FBgn0002158.html gene 16-Dec-15 2015_12 lethal "pupa,muscle system" FBgn0013231 E(var)182 E(var)182 http://flybase.net/reports/FBgn0013231.html gene 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0013541 l(2)ry53 lethal (2) ry53 http://flybase.net/reports/FBgn0013541.html gene "unnamed, l(2)53" 16-Dec-15 2015_12 lethal FBgn0001935 l(2)25Fa lethal (2) 25Fa http://flybase.net/reports/FBgn0001935.html gene "l(2)TE9, l(2)gdh-14" 16-Dec-15 2015_12 "lethal,recessive" FBgn0259413 C167 http://flybase.net/reports/FBgn0259413.html gene 16-Dec-15 2015_12 "visible,lethal" "wing,chaeta" FBgn0003329 scd sex combs distal http://flybase.net/reports/FBgn0003329.html gene "sex comb distal, l(1)9Fd" 16-Dec-15 2015_12 "prothoracic tarsal segment 2 & sex comb,sex comb,ectopic" FBgn0024692 fs(1)ne11 fs(1)ne11 http://flybase.net/reports/FBgn0024692.html gene ne11 16-Dec-15 2015_12 "female sterile,recessive" oocyte FBgn0044499 DTD44.4 DTD44.4 http://flybase.net/reports/FBgn0044499.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069084 sbe schraube http://flybase.net/reports/FBgn0069084.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0042155 CG18832 http://flybase.net/reports/FBgn0042155.html protein_coding_gene 16-Dec-15 2015_12 FBgn0086033 snoRNA:Me28S-A2486 http://flybase.net/reports/FBgn0086033.html snoRNA_gene "Me28S-A2486, CR34662, Me28S-Am2486" CR34662 16-Dec-15 2015_12 FBgn0085204 CG34175 http://flybase.net/reports/FBgn0085204.html protein_coding_gene CG34175 16-Dec-15 2015_12 FBgn0052195 CG32195 http://flybase.net/reports/FBgn0052195.html protein_coding_gene "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG32195 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0277432 M95 http://flybase.net/reports/FBgn0277432.html gene 16-Dec-15 2015_12 FBgn0069313 X-200-22 X-200-22 http://flybase.net/reports/FBgn0069313.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0031129 CG1324 http://flybase.net/reports/FBgn0031129.html FBgn0044683 protein_coding_gene anon-WO0140519.192 CG1324 16-Dec-15 2015_12 "viable,fertile,body color defective" mesothoracic tergum FBgn0001992 Cyp303a1 Cyp303a1 http://flybase.net/reports/FBgn0001992.html FBgn0032583 protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity" "0007423=sensory organ development, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "BG:DS02740.6, 303a1, CYP303A1-Dm, l(2)35Fb, CG4163, nompH, I(2)35Fb, Cyp303A1, lethal(2)35Fb" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG4163 16-Dec-15 2015_12 "uncoordinated,flightless,locomotor behavior defective,neurophysiology defective,partially lethal - majority die,recessive,lethal,neuroanatomy defective,chemosensitive behavior defective" "wing,macrochaeta,socket,trichogen cell" FBgn0000938 fs(2)A8 female sterile (2) A8 http://flybase.net/reports/FBgn0000938.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0036643 Syx8 Syntaxin 8 http://flybase.net/reports/FBgn0036643.html protein_coding_gene 0005484=SNAP receptor activity "0022008=neurogenesis, 0016192=vesicle-mediated transport, 0016081=synaptic vesicle docking, 0006906=vesicle fusion, 0007269=neurotransmitter secretion" "0005886=plasma membrane, 0031201=SNARE complex" "DmSyx8, Syntaxin, dSyntaxin8, CG4109, Dm Syx8, SYX8, syntaxin, Syx" IPR000727=Target SNARE coiled-coil homology domain CG4109 16-Dec-15 2015_12 ENSDARG00000041311(stx8) ENSXETG00000019532(stx8) ENSMUSG00000020903(Stx8) ENSG00000170310(STX8) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0065579 l(2)SH0943 lethal (2) SH0943 http://flybase.net/reports/FBgn0065579.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058388 CG40388 http://flybase.net/reports/FBgn0058388.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002903 mus306 mutagen-sensitive 306 http://flybase.net/reports/FBgn0002903.html gene 0006302=double-strand break repair mutagen sensitive 306 16-Dec-15 2015_12 "chemical sensitive,DNA repair defective,fertile,semidominant,female fertile" FBgn0065491 l(2)SH1233 lethal (2) SH1233 http://flybase.net/reports/FBgn0065491.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067085 K34 K34 http://flybase.net/reports/FBgn0067085.html gene 16-Dec-15 2015_12 "lethal,viable" FBgn0015439 l(1)5DEa lethal (1) 5DEa http://flybase.net/reports/FBgn0015439.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000358 Cp19 Chorion protein 19 http://flybase.net/reports/FBgn0000358.html protein_coding_gene 0005213=structural constituent of chorion "0007306=eggshell chorion assembly, 0007275=multicellular organismal development" 0042600=chorion "CP19, s19-1, S19, CG6524, Shell-19, Dms19, C.s19, s19, cp19, unnamed" "IPR005649=Chorion 2, IPR009611=Chorion S19, C-terminal" CG6524 16-Dec-15 2015_12 " oogenesis stage | >=stage S10 , adult stage | female , adult stage | female && oogenesis stage | stage S13-14 " follicle cell

adult stage | female " ovary

{ 0 swa6 } , ovary

, ovary

{ v mus101K451 } , ovary

{ v fs(1)A1059K1 } " viable FBgn0001360 l(1)1EFi lethal (1) 1EFi http://flybase.net/reports/FBgn0001360.html gene l(1)BA9 16-Dec-15 2015_12 lethal FBgn0001843 l(1)ts1843 lethal (1) ts1843 http://flybase.net/reports/FBgn0001843.html gene 16-Dec-15 2015_12 lethal FBgn0060323 l(3)S146705 lethal (3) S146705 http://flybase.net/reports/FBgn0060323.html gene 1467/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0259449 C407 http://flybase.net/reports/FBgn0259449.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0036522 CG7372 http://flybase.net/reports/FBgn0036522.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7372 16-Dec-15 2015_12 WBGene00021689(Y48G8AL.10) "viable,visible" mesothoracic tergum FBgn0011845 tRNA:D:96A transfer RNA:asp:96A http://flybase.net/reports/FBgn0011845.html "FBgn0051540, FBgn0060257" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033458=GAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[Asp-GTC], tRNA:asp:96A, CR31540, tRNA[Asp], chr3R.trna36-AspGTC, tRNA:D:GTC:AE002708-a, Asp.tRNA, tRNA[[Asp]], AE002708.trna30-AspGTC" CR31540 16-Dec-15 2015_12 FBgn0060657 l(3)S082808b lethal (3) S082808b http://flybase.net/reports/FBgn0060657.html gene 0828/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0004486 l(1)air13 lethal aberrant immune response 13 http://flybase.net/reports/FBgn0004486.html gene "air13, l(1)air[13]" 16-Dec-15 2015_12 "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0001307 Ki Kinked http://flybase.net/reports/FBgn0001307.html gene 16-Dec-15 2015_12 "viable,visible,dominant,heat sensitive,fertile" "macrochaeta,microchaeta" FBgn0261058 Sfp38D Seminal fluid protein 38D http://flybase.net/reports/FBgn0261058.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space IPR019617=Domain of unknown function DUF2489 CG42606 16-Dec-15 2015_12 FBgn0043029 l(2)42Ea lethal (2) 42Ea http://flybase.net/reports/FBgn0043029.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052507 CG32507 http://flybase.net/reports/FBgn0052507.html protein_coding_gene CG32507 16-Dec-15 2015_12 FBgn0051573 tRNA:CR31573 transfer RNA:CR31573 http://flybase.net/reports/FBgn0051573.html "FBgn0004266, FBgn0060113" tRNA_gene "0033423=CCA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:P:TGG:AE002708-b, chr3R.trna19-ProTGG, transfer RNA:?:90Ce, CR31573, AE002708.trna13-ProTGG, tRNA:-?:90Ce" CR31573 16-Dec-15 2015_12 FBgn0030979 CG14190 http://flybase.net/reports/FBgn0030979.html protein_coding_gene CG14190 16-Dec-15 2015_12 viable FBgn0016773 anon-70Db anon-70Db http://flybase.net/reports/FBgn0016773.html gene "gamma1 transcript, gamma1" 16-Dec-15 2015_12 FBgn0030816 CG16700 http://flybase.net/reports/FBgn0030816.html protein_coding_gene "0015495=gamma-aminobutyric acid:proton symporter activity, 0015171=amino acid transmembrane transporter activity" "0003333=amino acid transmembrane transport, 0022008=neurogenesis" 0008021=synaptic vesicle "IPR013057=Amino acid transporter, transmembrane domain" CG16700 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0019870 l(3)96Ad lethal (3) 96Ad http://flybase.net/reports/FBgn0019870.html gene "291.3, anon-96Ad" 16-Dec-15 2015_12 "lethal,recessive" FBgn0052071 CG32071 http://flybase.net/reports/FBgn0052071.html FBgn0036129 protein_coding_gene CG6261 CG32071 16-Dec-15 2015_12 FBgn0083994 CR41352 http://flybase.net/reports/FBgn0083994.html FBan0041352 non_protein_coding_gene CG41352 CR41352 16-Dec-15 2015_12 FBgn0037127 CG14566 http://flybase.net/reports/FBgn0037127.html protein_coding_gene CG14566 16-Dec-15 2015_12 FBgn0035624 Eaf6 Esa1-associated factor 6 http://flybase.net/reports/FBgn0035624.html protein_coding_gene 0016573=histone acetylation 0035267=NuA4 histone acetyltransferase complex "dEaf6, CG12756, Eaf6" "IPR015418=Histone H4 acetyltransferase, NuA4 complex, Eaf6" CG12756 16-Dec-15 2015_12 ENSDARG00000059167 WBGene00015001(B0025.4) ENSXETG00000017466(Q68ER9_XENTR) ENSMUSG00000028863(Meaf6) "viable,visible" mesothoracic tergum FBgn0267873 CR46161 http://flybase.net/reports/FBgn0267873.html pseudogene_attribute Mst35Ba-related CR46161 16-Dec-15 2015_12 FBgn0260987 vtd verthandi http://flybase.net/reports/FBgn0260987.html "FBgn0003993, FBgn0002297, FBgn0027941, FBgn0058222, FBan0017436, FBgn0026057" protein_coding_gene 0003682=chromatin binding "0010628=positive regulation of gene expression, 0090307=mitotic spindle assembly, 0000278=mitotic cell cycle, 0016322=neuron remodeling, 0070193=synaptonemal complex organization, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0006289=nucleotide-excision repair, 0007064=mitotic sister chromatid cohesion" "0005721=pericentric heterochromatin, 0005705=polytene chromosome interband, 0000775=chromosome, centromeric region, 0008278=cohesin complex, 0000795=synaptonemal complex, 0005634=nucleus" "Rad21/Scc1, Rad21, cohesin, Cohesin, CG40222, DmRAD21, RAD21, CG17436, lethal(3)80Fh, l(3)Lh3, 80Fh, Drad21, DRad21, VTD, l(3)80Fh, alpha kleisin, DRAD21, lethal 3, scc1, dRad21, l3, rad21, alpha-kleisin, Scc1, drad21" "IPR006910=Rad21/Rec8-like protein, N-terminal, IPR006909=Rad21/Rec8-like protein, C-terminal, eukaryotic, IPR023093=Rad21/Rec8-like protein, C-terminal" CG17436 16-Dec-15 2015_12 "ENSDARG00000006092(rad21),ENSDARG00000069772,ENSDARG00000035655(si:ch211-246f9.1)" WBGene00004737(scc-1) ENSXETG00000020783(RAD21) ENSMUSG00000022314(Rad21) ENSG00000164754(RAD21) " embryonic stage | stage 10 , larval stage | third instar , adult stage | male , embryonic stage | stage >=12 , embryonic stage | stage 11-14 , adult stage | female , embryonic stage , embryonic stage | stage 12 , pupal stage " " neuroblast

ventral compartment , eye-antennal disc | restricted

, midgut primordium

, embryonic brain

, embryonic/larval midgut | restricted

, embryonic/larval hindgut | restricted

, ventral nerve cord

, procephalic neuroblast

, neuroblast &&of larval brain

, inclusive hindgut primordium

" FBgn0260011 NimC4 Nimrod C4 http://flybase.net/reports/FBgn0260011.html "FBgn0028876, FBgn0084507" protein_coding_gene 0001786=phosphatidylserine binding "0006911=phagocytosis, engulfment, 0006909=phagocytosis, 0043277=apoptotic cell clearance, 0043652=engulfment of apoptotic cell" "0016021=integral component of membrane, 0005886=plasma membrane" "NimC4, six-microns-under, nimC4, nimrod C4, CT35247, BG:DS05899.3, six microns under, CG16876, simu" IPR000742=EGF-like domain CG16876 16-Dec-15 2015_12 FBgn0027345 fs(2)E9a fs(2)E9a http://flybase.net/reports/FBgn0027345.html FBgn0000962 gene "fs(2)E9, fs2.9, female sterile(2)E9" 16-Dec-15 2015_12 female fertile FBgn0038491 CG5292 http://flybase.net/reports/FBgn0038491.html FBgn0061398 protein_coding_gene "0008270=zinc ion binding, 0004131=cytosine deaminase activity" "BcDNA:RE41712, unnamed" "IPR002125=Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016193=Cytidine deaminase-like" CG5292 16-Dec-15 2015_12 ENSDARG00000041944(adat2) YJL035C(TAD2) WBGene00010436(JC8.4) ENSXETG00000009790(ADAT2) ENSMUSG00000019808(Adat2) ENSG00000189007(ADAT2) viable FBgn0030272 CG15201 http://flybase.net/reports/FBgn0030272.html FBgn0047048 protein_coding_gene 0005615=extracellular space "DIGF-5, BcDNA:RH06304" CG15201 16-Dec-15 2015_12 viable FBgn0260307 GSd328 http://flybase.net/reports/FBgn0260307.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" ventral nerve cord FBgn0082830 DC238 DC238 http://flybase.net/reports/FBgn0082830.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 FBgn0265254 CR44268 http://flybase.net/reports/FBgn0265254.html non_protein_coding_gene CR44268 16-Dec-15 2015_12 FBgn0031265 CG2794 http://flybase.net/reports/FBgn0031265.html protein_coding_gene "0016798=hydrolase activity, acting on glycosyl bonds, 0016773=phosphotransferase activity, alcohol group as acceptor" "IPR011611=Carbohydrate kinase PfkB, IPR002173=Carbohydrate/puine kinase, PfkB, conserved site, IPR029056=Ribokinase-like, IPR007342=Pseudouridine-5'-phosphate glycosidase" CG2794 16-Dec-15 2015_12 ENSDARG00000070830(zgc:136858) WBGene00020765(T24C12.3) "partially lethal - majority die,some die during pupal stage" FBgn0039635 CG11876 http://flybase.net/reports/FBgn0039635.html protein_coding_gene 0004739=pyruvate dehydrogenase (acetyl-transferring) activity "0006086=acetyl-CoA biosynthetic process from pyruvate, 0031122=cytoplasmic microtubule organization, 0006090=pyruvate metabolic process" "0045254=pyruvate dehydrogenase complex, 0005875=microtubule associated complex, 0005811=lipid particle, 0005739=mitochondrion" "E1beta, CG 11876, Pyruvate dehydrogenase E1beta subunit, PDHB" "IPR029061=Thiamin diphosphate-binding fold, IPR027110=Pyruvate dehydrogenase E1 component subunit beta, IPR005475=Transketolase-like, pyrimidine-binding domain, IPR013177=Domain of unknown function DUF1713, mitochondria, IPR009014=Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II" CG11876 16-Dec-15 2015_12 ENSDARG00000021346(pdhb) YBR221C(PDB1) WBGene00015413(C04C3.3) ENSXETG00000008685(pdhb) ENSMUSG00000021748(Pdhb) ENSG00000168291(PDHB) "wing disc | third instar larval stage,mitochondrionen-e16E" FBgn0016824 l(1)MZ11 lethal (1) MZ11 http://flybase.net/reports/FBgn0016824.html gene M11 16-Dec-15 2015_12 "lethal,recessive" FBgn0020569 anon-88Aa anon-88Aa http://flybase.net/reports/FBgn0020569.html gene unnamed 16-Dec-15 2015_12 FBgn0061108 l(3)S007818b lethal (3) S007818b http://flybase.net/reports/FBgn0061108.html gene 0078/18 16-Dec-15 2015_12 "lethal,recessive" FBgn0029535 CG14635 http://flybase.net/reports/FBgn0029535.html protein_coding_gene CG14635 16-Dec-15 2015_12 "viable,fertile" DRSC17945 I 1.74071811 -0.67331785 0.016961067 0.180855488 1.333578398 0.465194152 FBgn0022714 22w 22w http://flybase.net/reports/FBgn0022714.html gene 16-Dec-15 2015_12 mitotic cell cycle defective "nuclear chromosome,larval brain & nuclear chromosome" FBgn0004045 Yp1 Yolk protein 1 http://flybase.net/reports/FBgn0004045.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0005198=structural molecule activity" "0007548=sex differentiation, 0007296=vitellogenesis" "0005875=microtubule associated complex, 0005811=lipid particle" "YP[[1]], CG2985, fs(1)A1163, DmYP1, Yok protein 1, yp, yolk-protein 1, vitellogenin, yolk protein I, yolk protein 1, YP, VIT1Dm, yp-1, YP1, YP-1, fs(1)1163, yp1, yolk protein, VG1, YPI" "IPR000734=Triacylglycerol lipase family, IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal" CG2985 16-Dec-15 2015_12 "electrophoretic variant,female sterile,dominant,heat sensitive,recessive,female sterile soma-dependent,viable,body color defective" "adult fat body,heat sensitive,egg,mesothoracic tergum" FBgn0060981 l(3)S028317 lethal (3) S028317 http://flybase.net/reports/FBgn0060981.html gene 0283/17 16-Dec-15 2015_12 "lethal,recessive" FBgn0023025 l(2)KN13 lethal (2) KN13 http://flybase.net/reports/FBgn0023025.html gene 16-Dec-15 2015_12 FBgn0267210 CR45650 http://flybase.net/reports/FBgn0267210.html non_protein_coding_gene CR45650 16-Dec-15 2015_12 FBgn0083024 snoRNA:ë¬18S-640c snoRNA:ë¬18S-640c http://flybase.net/reports/FBgn0083024.html snoRNA_gene "psi18s-640c, CR34576" CR34576 16-Dec-15 2015_12 FBgn0261575 tobi target of brain insulin http://flybase.net/reports/FBgn0261575.html "FBgn0086730, FBgn0039330" protein_coding_gene "0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process 0017177=glucosidase II complex "alpha-Glucosidase, CG11909, CT33098" "IPR000322=Glycoside hydrolase family 31, IPR013785=Aldolase-type TIM barrel, IPR017853=Glycoside hydrolase superfamily" CG11909 16-Dec-15 2015_12 ENSDARG00000059678(LOC556083) ENSXETG00000019146(KIAA1161) ENSMUSG00000046312(AI464131) ENSG00000164976(KIAA1161) FBgn0033485 RpLP0-like Ribosomal protein LP0-like http://flybase.net/reports/FBgn0033485.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0042254=ribosome biogenesis" 0022625=cytosolic large ribosomal subunit "FBgn0033485, CG1381" IPR001790=Ribosomal protein L10P CG1381 16-Dec-15 2015_12 ENSDARG00000007130(zgc:110388) YKL009W(MRT4) WBGene00017347(F10E7.5) ENSXETG00000020828(BC077055.1) ENSMUSG00000028741(Mrto4) ENSG00000053372(MRTO4) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0030541 CG11584 http://flybase.net/reports/FBgn0030541.html protein_coding_gene IPR022727=Pupal cuticle protein C1 CG11584 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0259742 CG42360 http://flybase.net/reports/FBgn0259742.html "FBan0003579, FBgn0035037, FBgn0259706, FBgn0035038" protein_coding_gene "CG3579, CG13588" "IPR021869=Ribonuclease Zc3h12a-like, NYN domain" CG42360 16-Dec-15 2015_12 ENSDARG00000057491(n4bp1) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0265680 CR44487 http://flybase.net/reports/FBgn0265680.html non_protein_coding_gene lincRNA.185 CR44487 16-Dec-15 2015_12 FBgn0085212 CG34183 http://flybase.net/reports/FBgn0085212.html protein_coding_gene IPR007308=Protein of unknown function DUF408 CG34183 16-Dec-15 2015_12 "YER139C(RTR1),YDR066C(RTR2)" FBgn0025124 su(RpII140Z36)S4 su(RpII140Z36)S4 http://flybase.net/reports/FBgn0025124.html gene Z36[S4] 16-Dec-15 2015_12 FBgn0262482 CG43072 http://flybase.net/reports/FBgn0262482.html protein_coding_gene chr3L_21058978_21059336.0 CG43072 16-Dec-15 2015_12 FBgn0004664 ms(3)HO5A male sterile (3) HO5A http://flybase.net/reports/FBgn0004664.html "FBgn0002834, FBgn0002836, FBgn0005313" gene "male sterile(3)m1, ms(3)ml[5A], ms(1)m1, ms(3)m1" 16-Dec-15 2015_12 "male sterile,recessive" testis FBgn0028081 l(3)S085301 lethal (3) S085301 http://flybase.net/reports/FBgn0028081.html gene 0853/01 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027195 l(2)39CDa lethal (2) 39CDa http://flybase.net/reports/FBgn0027195.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0035781 CG8560 http://flybase.net/reports/FBgn0035781.html protein_coding_gene "0004180=carboxypeptidase activity, 0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" 0006508=proteolysis CT14378 "IPR000834=Peptidase M14, carboxypeptidase A, IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR009020=Proteinase inhibitor, propeptide" CG8560 16-Dec-15 2015_12 "WBGene00020281(T06A4.1),WBGene00021213(Y18H1A.9)" viable FBgn0024563 l(3)L6332 lethal (3) L6332 http://flybase.net/reports/FBgn0024563.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0086026 snoRNA:Me28S-G2596 http://flybase.net/reports/FBgn0086026.html snoRNA_gene "CR34655, Me28S-Gm2596" CR34655 16-Dec-15 2015_12 FBgn0014997 snRNA:U1:21D::snRNA:U1:82Ea snRNA:U1:21D::snRNA:U1:82Ea http://flybase.net/reports/FBgn0014997.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023048 l(1)3Ao lethal (1) 3Ao http://flybase.net/reports/FBgn0023048.html gene 15-Nov 16-Dec-15 2015_12 "lethal,recessive" FBgn0267915 CR46196 http://flybase.net/reports/FBgn0267915.html non_protein_coding_gene lincRNA.60 CR46196 16-Dec-15 2015_12 FBgn0259551 B1512 http://flybase.net/reports/FBgn0259551.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing vein L3,wing margin,wing sensillum,ectopic,tarsal segment,antennal segment,arista,leg,third segment of antenna,chaeta" FBgn0000982 fs(2)HO297 female sterile (2) HO297 http://flybase.net/reports/FBgn0000982.html gene fs(2)297A 16-Dec-15 2015_12 FBgn0034318 CG14500 http://flybase.net/reports/FBgn0034318.html protein_coding_gene 0030246=carbohydrate binding "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG14500 16-Dec-15 2015_12 viable FBgn0085740 CR40508 http://flybase.net/reports/FBgn0085740.html FBan0040508 rRNA_gene CR40508 16-Dec-15 2015_12 FBgn0265676 CR44483 http://flybase.net/reports/FBgn0265676.html non_protein_coding_gene CR44483 16-Dec-15 2015_12 FBgn0267703 CR46036 http://flybase.net/reports/FBgn0267703.html non_protein_coding_gene CR46036 16-Dec-15 2015_12 FBgn0069439 EMS2 EMS2 http://flybase.net/reports/FBgn0069439.html gene 0009651=response to salt stress 16-Dec-15 2015_12 FBgn0086036 snoRNA:Me18S-A934 http://flybase.net/reports/FBgn0086036.html snoRNA_gene "Me18S-Am934, CR34665" CR34665 16-Dec-15 2015_12 FBgn0023055 l(1)3ABa lethal (1) 3ABa http://flybase.net/reports/FBgn0023055.html gene "D3/22.61, A2/7" 16-Dec-15 2015_12 "lethal,recessive" FBgn0087011 CG41520 http://flybase.net/reports/FBgn0087011.html "FBan0041520, FBgn0085665, FBgn0058067, FBgn0039962, FBgn0058109" protein_coding_gene "CG17443, CG40067, CG40109" "IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG41520 16-Dec-15 2015_12 "ENSDARG00000030364(angpt1),ENSDARG00000020741(fga),ENSDARG00000014946(LOC100332825),ENSDARG00000053906(angpt2)" WBGene00020516(T15B7.1) ENSXETG00000026093(FGA) "ENSMUSG00000031465(Angpt2),ENSMUSG00000022309(Angpt1),ENSMUSG00000027460(Angpt4)" FBgn0032509 CG6523 http://flybase.net/reports/FBgn0032509.html protein_coding_gene "0009055=electron carrier activity, 0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" 0045454=cell redox homeostasis "Grx3, Grx4" "IPR012336=Thioredoxin-like fold, IPR013766=Thioredoxin domain, IPR002109=Glutaredoxin, IPR004480=Monothiol glutaredoxin-related" CG6523 16-Dec-15 2015_12 ENSDARG00000031439(glrx3) "YER174C(GRX4),YDR098C(GRX3)" WBGene00017062(D2063.3) ENSXETG00000011308(txnl2) ENSMUSG00000031068(Glrx3) ENSG00000108010(GLRX3) viable FBgn0021876 l(2)k13704 lethal (2) k13704 http://flybase.net/reports/FBgn0021876.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011051 l(1)Q4 lethal (1) Q4 http://flybase.net/reports/FBgn0011051.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0020526 mit(3)R72 mitotic R72 http://flybase.net/reports/FBgn0020526.html gene 16-Dec-15 2015_12 FBgn0085239 CG34210 http://flybase.net/reports/FBgn0085239.html protein_coding_gene IPR029375=Protein of unknown function DUF4558 CG34210 16-Dec-15 2015_12 FBgn0014252 l(2)60Ae lethal (2) 60Ae http://flybase.net/reports/FBgn0014252.html gene 16-Dec-15 2015_12 lethal FBgn0030768 CG9723 http://flybase.net/reports/FBgn0030768.html protein_coding_gene IPR019358=NEMP family CG9723 16-Dec-15 2015_12 ENSDARG00000061062 WBGene00017328(F10C5.2) ENSXETG00000004426(BC091583.1) ENSMUSG00000040195(Tmem194) "ENSG00000166881(TMEM194A),ENSG00000189362(TMEM194B)" viable FBgn0259178 5PtaseI 5PtaseI http://flybase.net/reports/FBgn0259178.html "FBgn0051107, FBgn0039263, FBgn0051110, FBgn0064867" protein_coding_gene "0046030=inositol trisphosphate phosphatase activity, 0004445=inositol-polyphosphate 5-phosphatase activity" "0046855=inositol phosphate dephosphorylation, 0046856=phosphatidylinositol dephosphorylation, 0016311=dephosphorylation" "IPP, dm5PtaseI, CG42283, BcDNA:RE64196, CG7613, CG31110, CG31107" "IPR000300=Inositol polyphosphate-related phosphatase, IPR005135=Endonuclease/exonuclease/phosphatase" CG42283 16-Dec-15 2015_12 FBgn0028239 l(3)S001925 lethal (3) S001925 http://flybase.net/reports/FBgn0028239.html gene 0019/25 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0021971 l(2)k10003a lethal (2) k10003a http://flybase.net/reports/FBgn0021971.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027538 ë_4GalNAcTA ë_4GalNAcTA http://flybase.net/reports/FBgn0027538.html FBgn0062226 protein_coding_gene "0033207=beta-1,4-N-acetylgalactosaminyltransferase activity, 0033842=N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity, 0008376=acetylgalactosaminyltransferase activity" "0007291=sperm individualization, 0006044=N-acetylglucosamine metabolic process, 0005975=carbohydrate metabolic process, 0008344=adult locomotory behavior, 0007528=neuromuscular junction development, 0006688=glycosphingolipid biosynthetic process, 0009247=glycolipid biosynthetic process" 0005794=Golgi apparatus "b4GalNAcTA, beta4GalTA, beta4GalNacTA, beta4GalNAcTA, DmGalT, beta4GalNAcT1, BcDNA:GH13356, beta4Gal-NAcTA, CG8536, anon-WO0118547.128, dbeta4GalTA, beta1,4-N-acetylgalactosaminyltransferase" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR003859=Beta-1,4-galactosyltransferase, IPR027995=Galactosyltransferase, N-terminal, IPR027791=Galactosyltransferase, C-terminal" CG8536 16-Dec-15 2015_12 "ENSDARG00000052326(zgc:154116),ENSDARG00000002634(LOC100332735),ENSDARG00000018853(wu:fd56f09),ENSDARG00000004798(zgc:101780),ENSDARG00000062329(LOC561756)" WBGene00000269(bre-4) "ENSXETG00000002874(TGas115g12.1),ENSXETG00000023017(b4galt3),ENSXETG00000003265(B4GALT2),ENSXETG00000024146(b4galt1),ENSXETG00000023016(B4GALT4)" "ENSMUSG00000028413(B4galt1),ENSMUSG00000028541(B4galt2),ENSMUSG00000052423(B4galt3),ENSMUSG00000022793(B4galt4)" "ENSG00000117411(B4GALT2),ENSG00000086062(B4GALT1),ENSG00000158850(B4GALT3),ENSG00000121578(B4GALT4)" "fertile,viable,bang sensitive,locomotor behavior defective,neuroanatomy defective,neurophysiology defective,sleep defective" "embryonic/larval neuromuscular junction,NMJ bouton,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,sarcomere & abdominal ventral longitudinal muscle 3ë_4GalNAcTA20.1),sarcomere & abdominal ventral longitudinal muscle 4ë_4GalNAcTA20.1)" FBgn0010647 l(2)08307a lethal (2) 08307a http://flybase.net/reports/FBgn0010647.html gene l(2)08307 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0010041 GstD5 Glutathione S transferase D5 http://flybase.net/reports/FBgn0010041.html FBgn0038024 protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "gstd5, DmGST24, D5, Gst, Glutathione S transferase D24, glutathione-S-transferase D5, GST, GSTD5, gstD24, GstD24, DmGSTD5, CG12242" "IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold" CG12242 16-Dec-15 2015_12 YNL229C(URE2) viable FBgn0085686 CG41555 http://flybase.net/reports/FBgn0085686.html FBan0041555 protein_coding_gene 16-Dec-15 2015_12 FBgn0039685 Obp99b Odorant-binding protein 99b http://flybase.net/reports/FBgn0039685.html "FBgn0063111, FBgn0064137" protein_coding_gene 0005549=odorant binding "0042048=olfactory behavior, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0019236=response to pheromone, 0007606=sensory perception of chemical stimulus" 0005576=extracellular region "CG7592, obp99b, turn on sex-specificity, tsx, Odorant binding protein 99B, General odorant-binding protein 99b precursor, 99b, Odorant Binding Protein 99b, OBP99b, Odordant-binding protein 99b, DmelObp99b, Obp99d, BcDNA:LP06572" IPR006170=Pheromone/general odorant binding protein CG7592 16-Dec-15 2015_12 "mating defective,female,viable" DRSC16264 E -0.051477676 -1.147726077 -1.871766633 -0.33853945 0.646867704 -0.792500403 FBgn0039900 Syt7 Synaptotagmin 7 http://flybase.net/reports/FBgn0039900.html FBgn0039901 protein_coding_gene 0005544=calcium-dependent phospholipid binding "0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0016079=synaptic vesicle exocytosis, 0006887=exocytosis" "0016020=membrane, 0008021=synaptic vesicle, 0016528=sarcoplasm, 0016021=integral component of membrane, 0005764=lysosome, 0031982=vesicle" "Syt VII, Synaptotagmin VII, Syt 7, synaptotagmin 7, dsyt7, CG2381, SYT7, Syt7, unnamed, syt7, CG10322" "IPR001565=Synaptotagmin, IPR015427=Synaptotagmin 7, IPR000008=C2 domain" CG2381 16-Dec-15 2015_12 ENSDARG00000063568(LOC561429) ENSMUSG00000024743(Syt7) ENSG00000011347(SYT7) viable FBgn0260779 GatA "Glutamyl-tRNA(Gln) amidotransferase, subunit A" http://flybase.net/reports/FBgn0260779.html "FBgn0086360, FBgn0027658, FBgn0067781, FBgn0028061" protein_coding_gene 0050567=glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity "0006412=translation, 0048477=oogenesis, 0030717=karyosome formation" 0005739=mitochondrion "0929/02, glutamyl-tRNA amidotransferase subunit A, benedict, lethal (3) S092902, CG6007, gatA, glutamyl-tRNA amidotransferase A, l(3)S092902, bene" "IPR000120=Amidase, IPR023631=Amidase signature domain, IPR004412=Glutamyl-tRNA(Gln) amidotransferase A subunit" CG6007 16-Dec-15 2015_12 ENSDARG00000032704(qrsl1) YMR293C(HER2) WBGene00021508(Y41D4A.6) ENSXETG00000027717(QRSL1) ENSMUSG00000019863(Qrsl1) ENSG00000130348(QRSL1) FBgn0259569 B2022 http://flybase.net/reports/FBgn0259569.html gene 16-Dec-15 2015_12 visible "anterior crossvein,tarsal segment" FBgn0001492 l(1)10Bc lethal (1) 10Bc http://flybase.net/reports/FBgn0001492.html gene "l(1)G15, l(1)GLM15, 10Bb" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,egg,dorsal appendage" FBgn0001242 hypoA hypoactive A http://flybase.net/reports/FBgn0001242.html gene 0007629=flight behavior hypoactive-A 16-Dec-15 2015_12 "bang sensitive,optomotor response defective,locomotor behavior defective,flight defective" FBgn0259411 C752 http://flybase.net/reports/FBgn0259411.html gene 16-Dec-15 2015_12 visible "wing,chaeta,ectopic" FBgn0060600 l(3)S091904b lethal (3) S091904b http://flybase.net/reports/FBgn0060600.html gene 0919/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0003459 stwl stonewall http://flybase.net/reports/FBgn0003459.html protein_coding_gene 0003677=DNA binding "0008104=protein localization, 0042262=DNA protection, 0006325=chromatin organization, 0030727=germarium-derived female germ-line cyst formation, 0006355=regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated, 0030718=germ-line stem cell maintenance, 0035167=larval lymph gland hemopoiesis, 0070828=heterochromatin organization, 0007294=germarium-derived oocyte fate determination" "0005634=nucleus, 0005730=nucleolus, 0005654=nucleoplasm" "snw, 84, alpha transcript, Stonewall, CG3836, fs(3)02024, Stwl" "IPR006578=MADF domain, IPR004210=BESS motif" CG3836 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-7 " " female germline stem cell

, germarium region 1--3

, oocyte

, nurse cell

" "lethal,heat sensitive,hyperplasia,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,recessive,viable,fertile,neuroanatomy defective,male fertile,suppressor of variegation,dominant,chemical sensitive,female fertile,visible" "wing margin,wing pouch,wing disc,wing hinge,wing hinge primordium,eye,ovary,egg chamber,embryonic/larval salivary gland | larval stage,neurite | pharate adult stage,germline cell,female,heat sensitive,female germline stem cell,somatic clone,supernumerary" FBgn0021830 l(2)k16005 lethal (2) k16005 http://flybase.net/reports/FBgn0021830.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267819 CR46144 http://flybase.net/reports/FBgn0267819.html non_protein_coding_gene CR46144 16-Dec-15 2015_12 FBgn0019766 l(1)54B2 lethal (1) 54B2 http://flybase.net/reports/FBgn0019766.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037019 Pex16 Peroxin 16 http://flybase.net/reports/FBgn0037019.html protein_coding_gene "0048137=spermatocyte division, 0007031=peroxisome organization, 0042760=very long-chain fatty acid catabolic process, 0007283=spermatogenesis" 0005777=peroxisome "CG3947, DmelPex16, PEX16, peroxin 16, pex16" "IPR013919=Peroxisome membrane protein, Pex16" CG3947 16-Dec-15 2015_12 ENSDARG00000058202(pex16) ENSXETG00000001027(PEX16) ENSMUSG00000027222(Pex16) ENSG00000121680(PEX16) "viable,eye color defective,flight defective,recessive,locomotor behavior defective,short lived,neuroanatomy defective,male sterile,small body,fertile,cytokinesis defective" "peroxisomeNP5021,peroxisomenos.UTR.THsimVP16,peroxisome,dendrite,testis,lobula plate" FBgn0013949 Elal Elastin-like http://flybase.net/reports/FBgn0013949.html protein_coding_gene 0035094=response to nicotine "elastin-like, Ela, CG7021" CG7021 16-Dec-15 2015_12 viable FBgn0004187 snRNA:U1:95Cc small nuclear RNA U1 at 95Cc http://flybase.net/reports/FBgn0004187.html "FBgn0003915, FBgn0003918, FBgn0051185" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005685=U1 snRNP "U1-95.3, small nuclear RNA U1, U1, 95C U1, U1 snRNA, K5, U1:95C, CR31185, U1snRNA95Cc, snRNA:U1, U1snRNA, snRNA-U1-95.3, U1:95Cc, U1c-95Cc" CR31185 16-Dec-15 2015_12 FBgn0267111 CR45551 http://flybase.net/reports/FBgn0267111.html non_protein_coding_gene "lincRNA.724, lincRNA.723" CR45551 16-Dec-15 2015_12 FBgn0035521 VhaM9.7-a Vacuolar H+ ATPase M9.7 subunit a http://flybase.net/reports/FBgn0035521.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0015078=hydrogen ion transmembrane transporter activity" 0015991=ATP hydrolysis coupled proton transport "0005886=plasma membrane, 0016471=vacuolar proton-transporting V-type ATPase complex, 0033179=proton-transporting V-type ATPase, V0 domain, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "CG1268, vhaM9.7-1, Vacuolar H[+] ATPase subunit M9.7-a" "IPR017385=ATPase, V0 complex, subunit e1/e2, metazoa, IPR008389=ATPase, V0 complex, subunit e1/e2" CG1268 16-Dec-15 2015_12 "ENSDARG00000059057(zgc:109987),ENSDARG00000039642(zgc:103433)" WBGene00009882(vha-17) ENSXETG00000024781(ATP6V0E1) "ENSMUSG00000039347(Atp6v0e2),ENSMUSG00000015575(Atp6v0e)" ENSG00000113732(ATP6V0E1) "partially lethal - majority die,some die during pupal stage" FBgn0030537 CG12480 http://flybase.net/reports/FBgn0030537.html protein_coding_gene CG12480 16-Dec-15 2015_12 "ENSXETG00000021168(),ENSXETG00000010508(),ENSXETG00000014464(CIZ1),ENSXETG00000026829(),ENSXETG00000021960()" viable FBgn0000782 fs(1)A1528 female sterile (1) A1528 http://flybase.net/reports/FBgn0000782.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,non-rescuable maternal effect" egg FBgn0015854 anon-12Ea anon-12Ea http://flybase.net/reports/FBgn0015854.html gene unnamed 16-Dec-15 2015_12 FBgn0023030 l(2)C43 lethal (2) C43 http://flybase.net/reports/FBgn0023030.html gene unnamed 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0000740 fs(1)A120 female sterile (1) A120 http://flybase.net/reports/FBgn0000740.html gene 0048477=oogenesis "fs(1)571, fs(1)120" 16-Dec-15 2015_12 "female sterile,recessive,female sterile soma-dependent,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect,embryo" FBgn0036677 CG13023 http://flybase.net/reports/FBgn0036677.html protein_coding_gene CG13023 16-Dec-15 2015_12 viable FBgn0065713 l(2)SH0581 lethal (2) SH0581 http://flybase.net/reports/FBgn0065713.html gene l(2)SH2 0581 16-Dec-15 2015_12 "lethal,recessive" FBgn0003350 sdx spreadex http://flybase.net/reports/FBgn0003350.html gene spx 16-Dec-15 2015_12 semi-fertile "wing,abdomen,female" FBgn0083016 snoRNA:ë¬18S-841d snoRNA:ë¬18S-841d http://flybase.net/reports/FBgn0083016.html snoRNA_gene "CR34555, psi18S-841d, Psi18S-841d" CR34555 16-Dec-15 2015_12 FBgn0265059 CR44170 http://flybase.net/reports/FBgn0265059.html non_protein_coding_gene CR44170 16-Dec-15 2015_12 FBgn0069215 gl-l glass-like http://flybase.net/reports/FBgn0069215.html gene 0048749=compound eye development 16-Dec-15 2015_12 FBgn0032271 CG7329 http://flybase.net/reports/FBgn0032271.html protein_coding_gene 0004806=triglyceride lipase activity ORE-4 "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG7329 16-Dec-15 2015_12 ENSDARG00000018529(lipf) "YLR020C(YEH2),YLL012W(YEH1)" "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" viable FBgn0038550 CG17801 http://flybase.net/reports/FBgn0038550.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG17801 16-Dec-15 2015_12 WBGene00004335(ref-2) "viable,fertile,female fertile" FBgn0040014 CG17412 http://flybase.net/reports/FBgn0040014.html protein_coding_gene 16-Dec-15 2015_12 FBgn0082363 EP605 EP605 http://flybase.net/reports/FBgn0082363.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0266494 s-112.1 http://flybase.net/reports/FBgn0266494.html gene 16-Dec-15 2015_12 FBgn0040266 Transpac\gag gag http://flybase.net/reports/FBgn0040266.html transposable_element_gene 16-Dec-15 2015_12 FBgn0262553 Mod(GMroX1)163 http://flybase.net/reports/FBgn0262553.html gene 16-Dec-15 2015_12 FBgn0264643 disjointed disjointed http://flybase.net/reports/FBgn0264643.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" Disjointed 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0024432 Dlc90F Dynein light chain 90F http://flybase.net/reports/FBgn0024432.html "FBgn0010833, FBgn0017467" protein_coding_gene "0051959=dynein light intermediate chain binding, 0045505=dynein intermediate chain binding, 0042623=ATPase activity, coupled, 0042803=protein homodimerization activity" "0008340=determination of adult lifespan, 2001019=positive regulation of retrograde axon cargo transport, 0007018=microtubule-based movement, 0007286=spermatid development, 0007067=mitotic nuclear division" "0005875=microtubule associated complex, 0005868=cytoplasmic dynein complex, 0030286=dynein complex" "unnamed, TcTex-1, l(3)04091, dtctex-1, dlc90F, Tctex1, CG12363, bs35g12.y1, Tctex-1, dynein light chain; tctex-1, Tctex, tctex, tctex-1" IPR005334=Tctex-1 CG12363 16-Dec-15 2015_12 "ENSDARG00000071348(si:dkey-148f10.4),ENSDARG00000045909(si:ch211-51e12.3)" WBGene00008764(dylt-1) "ENSMUSG00000000579(Dynlt1c),ENSMUSG00000079732(Dynlt1f),ENSMUSG00000079728(Dynlt1e)" ENSG00000146425(DYNLT1) "male sterile,recessive,partially lethal - majority die,viable,male semi-sterile,male fertile,long lived,visible,body color defective" "spermatozoon,spermatid,spermatocyte,centrosomeExel6178),Nebenkern,trichogen cell,mesothoracic tergum" FBgn0060862 l(3)S047523 lethal (3) S047523 http://flybase.net/reports/FBgn0060862.html gene 0475/23 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0265457 CR44357 http://flybase.net/reports/FBgn0265457.html non_protein_coding_gene CR44357 16-Dec-15 2015_12 FBgn0028418 Lk Leucokinin http://flybase.net/reports/FBgn0028418.html FBgn0036429 protein_coding_gene "0005179=hormone activity, 0005184=neuropeptide hormone activity, 0008613=diuretic hormone activity" "0019722=calcium-mediated signaling, 0007218=neuropeptide signaling pathway, 0007204=positive regulation of cytosolic calcium ion concentration, 0007589=body fluid secretion, 2000252=negative regulation of feeding behavior" 0005615=extracellular space "Drosokinin, Leucokinin-like, LCK, DLK, CG13480, lk, myokinin-like, Lk, drosokinin, kinin, LK, leucokinin precursor, leukokinin, leucokinin, pp, leukokinin neuropeptide, Leucokinin-1, Leukokinin, Leucokinin, Leuk, Drm-KIN" CG13480 16-Dec-15 2015_12 viable FBgn0000861 fs(1)M55 female sterile (1) M55 http://flybase.net/reports/FBgn0000861.html gene 16-Dec-15 2015_12 female sterile FBgn0043997 Su(rst)C94 Su(rst)C94 http://flybase.net/reports/FBgn0043997.html gene 0001745=compound eye morphogenesis C94 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0040607 CG14244 http://flybase.net/reports/FBgn0040607.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG14244 16-Dec-15 2015_12 viable FBgn0035315 CG8960 http://flybase.net/reports/FBgn0035315.html protein_coding_gene CG8960 16-Dec-15 2015_12 viable FBgn0040333 brv3 brivido-3 http://flybase.net/reports/FBgn0040333.html FBgn0029632 protein_coding_gene "0005509=calcium ion binding, 0005262=calcium channel activity" "0006816=calcium ion transport, 0009409=response to cold" 0016020=membrane "CG13762, EG:BACR7C10.7, CT33244" "IPR003915=Polycystic kidney disease type 2 protein, IPR013122=Polycystin cation channel, PKD1/PKD2" CG13762 16-Dec-15 2015_12 "cold stress response defective,viable" FBgn0263509 CR43498 http://flybase.net/reports/FBgn0263509.html non_protein_coding_gene CR43498 16-Dec-15 2015_12 FBgn0086082 snoRNA:Or-CD11 http://flybase.net/reports/FBgn0086082.html snoRNA_gene "Or-CD11, orphan CD11, CR34711" CR34711 16-Dec-15 2015_12 FBgn0052820 CG32820 http://flybase.net/reports/FBgn0052820.html protein_coding_gene tektin IPR000435=Tektin CG32820 16-Dec-15 2015_12 ENSDARG00000045038(tekt3) WBGene00019828(R02E12.4) ENSXETG00000019577(tekt3) "ENSMUSG00000042189(Tekt3),ENSMUSG00000039179(Tekt5)" "ENSG00000125409(TEKT3),ENSG00000153060(TEKT5)" FBgn0084167 LA00508 LA00508 http://flybase.net/reports/FBgn0084167.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014026 RpL7A Ribosomal protein L7A http://flybase.net/reports/FBgn0014026.html protein_coding_gene 0003735=structural constituent of ribosome "0000022=mitotic spindle elongation, 0051298=centrosome duplication, 0051297=centrosome organization, 0006412=translation, 0007052=mitotic spindle organization, 0042254=ribosome biogenesis" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "Surf3/rpL7a, Rp L7A, L7A, RpL7a, L7a, CG3314, Surf-3/rpL7a" "IPR001921=Ribosomal protein L7A/L8, IPR029064=50S ribosomal protein L30e-like, IPR018492=Ribosomal protein L7Ae/L8/Nhp2 family, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR004037=Ribosomal protein L7Ae conserved site" CG3314 16-Dec-15 2015_12 ENSDARG00000019230(rpl7a) "YHL033C(RPL8A),YLL045C(RPL8B)" WBGene00004419(rpl-7A) ENSXETG00000005009(rpl7a) "ENSMUSG00000066452(Gm8226),ENSMUSG00000062647(Rpl7a),ENSMUSG00000062758(Gm16477),ENSMUSG00000062358,ENSMUSG00000068579(Rpl7a-ps3),ENSMUSG00000070289(Rpl7a-ps10),ENSMUSG00000071052(Rpl7a-ps5),ENSMUSG00000070778(Rpl7a-ps8),ENSMUSG00000062874,ENSMUSG00000078177(Gm4877)" ENSG00000148303(RPL7A) embryonic stage -- adult stage "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC18709 IEK -2.402057537 -0.552404103 1.555604982 -2.805914739 0.916620787 3.82610895 FBgn0028932 CG16890 http://flybase.net/reports/FBgn0028932.html protein_coding_gene 0005515=protein binding BG:DS00797.4 IPR019129=Folate-sensitive fragile site protein Fra10Ac1 CG16890 16-Dec-15 2015_12 ENSDARG00000016608(fra10ac1) WBGene00086566(C08H9.16) ENSXETG00000026367(C10orf4) ENSMUSG00000054237(5730455O13Rik) ENSG00000148690(FRA10AC1) "viable,fertile" DRSC01890 K 0.025850593 -0.454425889 -1.007377534 0.112200837 -0.117288693 2.097772151 FBgn0010064 M(2)38k M(2)38k http://flybase.net/reports/FBgn0010064.html gene M(2)[38k4] 16-Dec-15 2015_12 "Minute,visible" macrochaeta FBgn0086320 JR107 http://flybase.net/reports/FBgn0086320.html gene 16-Dec-15 2015_12 "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0029021 l(3)77CDa lethal (3) 77CDa http://flybase.net/reports/FBgn0029021.html gene 16-Dec-15 2015_12 "lethal,recessive,wild-type" FBgn0005103 gusA gustatory A http://flybase.net/reports/FBgn0005103.html gene 0030536=larval feeding behavior 16-Dec-15 2015_12 "taste perception defective,cold sensitive" FBgn0028615 l(2)W10 lethal (2) W10 http://flybase.net/reports/FBgn0028615.html gene l(2R)W10 16-Dec-15 2015_12 "lethal,recessive" FBgn0040695 CG14976 http://flybase.net/reports/FBgn0040695.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267483 CR45833 http://flybase.net/reports/FBgn0267483.html non_protein_coding_gene CR45833 16-Dec-15 2015_12 FBgn0051189 CG31189 http://flybase.net/reports/FBgn0051189.html FBgn0038848 protein_coding_gene 0005615=extracellular space "CG7096-C, CG7096" IPR010562=Haemolymph juvenile hormone binding CG31189 16-Dec-15 2015_12 viable FBgn0263558 mir-4980 mir-4980 stem loop http://flybase.net/reports/FBgn0263558.html miRNA_gene "CR43543, dme-mir-4980" CR43543 16-Dec-15 2015_12 FBgn0014965 gypsy\gag gypsy element gag http://flybase.net/reports/FBgn0014965.html transposable_element_gene "gag, ORF1, GAG, Gag" 16-Dec-15 2015_12 FBgn0037406 Osi1 Osiris 1 http://flybase.net/reports/FBgn0037406.html protein_coding_gene 0005887=integral component of plasma membrane "osi1, Osiris, CG15585" IPR012464=Protein of unknown function DUF1676 CG15585 16-Dec-15 2015_12 viable FBgn0011094 l(1)Q54 lethal (1) Q54 http://flybase.net/reports/FBgn0011094.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0035021 CG4622 http://flybase.net/reports/FBgn0035021.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "IPR001878=Zinc finger, CCHC-type, IPR006568=PSP, proline-rich" CG4622 16-Dec-15 2015_12 ENSDARG00000034982(zcchc8) "WBGene00014018(ZK632.11),WBGene00021332(Y34D9A.7)" ENSXETG00000007797(ZCCHC8) ENSMUSG00000029427(Zcchc8) ENSG00000033030(ZCCHC8) "viable,fertile" FBgn0013325 RpL11 Ribosomal protein L11 http://flybase.net/reports/FBgn0013325.html "FBgn0021801, FBgn0062462" protein_coding_gene "0005515=protein binding, 0003735=structural constituent of ribosome" "0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0006412=translation, 0051298=centrosome duplication" "0005730=nucleolus, 0005840=ribosome, 0000228=nuclear chromosome, 0005703=polytene chromosome puff, 0005737=cytoplasm, 0022625=cytosolic large ribosomal subunit" "Rp L11, ribosomal protein DL11, RPL11, chr2R:14957112..14957299, EST A, BcDNA:LD17235, CG7726, l(2)k16914, L11, DL11, 60S ribosomal protein L11" "IPR020929=Ribosomal protein L5, conserved site, IPR022803=Ribosomal protein L5 domain, IPR031309=Ribosomal protein L5, C-terminal, IPR031310=Ribosomal protein L5, N-terminal, IPR002132=Ribosomal protein L5" CG7726 16-Dec-15 2015_12 ENSDARG00000043509(rpl11) "YPR102C(RPL11A),YGR085C(RPL11B)" "WBGene00004423(rpl-11.2),WBGene00004422(rpl-11.1)" ENSXETG00000001178(RPL11) "ENSMUSG00000059291(Rpl11),ENSMUSG00000070343(Gm10288),ENSMUSG00000058064(Gm10036),ENSMUSG00000066592(Gm7589)" ENSG00000142676(RPL11) embryonic stage -- adult stage "lethal,recessive" DRSC07537 IEK -2.489937133 -2.24200888 1.791292245 -3.948174523 3.608686076 2.673291962 FBgn0037071 CG7632 http://flybase.net/reports/FBgn0037071.html protein_coding_gene "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG7632 16-Dec-15 2015_12 ENSDARG00000032340(serhl) "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" ENSMUSG00000058586(Serhl) "ENSG00000183569(SERHL2),ENSG00000172250" viable FBgn0003938 snRNA:U5:63BC small nuclear RNA U5 at 63A http://flybase.net/reports/FBgn0003938.html FBgn0003932 snRNA_gene "0000398=mRNA splicing, via spliceosome" 0005682=U5 snRNP "small nuclear RNA U5, U5snRNA63A, U5, U5 snRNA, U5:63BC, snRNA[[3]], K2, snRNA:U5:63A, snRNA3, U5snRNA, chr3L:3074339..3074497, 63B U5, U5-63BC, U5 small nuclear RNA, U5 snRNA 63BC, snRNA4, snRNA:U5, CR32908, dU5" CR32908 16-Dec-15 2015_12 FBgn0034871 CG3906 http://flybase.net/reports/FBgn0034871.html protein_coding_gene IPR010629=Insect allergen-related CG3906 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0263774 CG43691 http://flybase.net/reports/FBgn0263774.html "FBgn0033832, FBgn0033831" protein_coding_gene "CG17050, CG17049" CG43691 16-Dec-15 2015_12 FBgn0035501 CG1299 http://flybase.net/reports/FBgn0035501.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "c-SP18, SP18" "IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG1299 16-Dec-15 2015_12 ENSG00000178297(TMPRSS9) viable FBgn0260810 EP3-1789 http://flybase.net/reports/FBgn0260810.html gene 16-Dec-15 2015_12 FBgn0001532 l(1)11Fb lethal (1) 11Fb http://flybase.net/reports/FBgn0001532.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0032289 CG6431 http://flybase.net/reports/FBgn0032289.html protein_coding_gene 0004806=triglyceride lipase activity chr2L_10724193_10724543.0 "IPR029058=Alpha/Beta hydrolase fold, IPR013818=Lipase, N-terminal, IPR000734=Triacylglycerol lipase family" CG6431 16-Dec-15 2015_12 viable FBgn0029890 CG4095 http://flybase.net/reports/FBgn0029890.html protein_coding_gene 0004333=fumarate hydratase activity "0006099=tricarboxylic acid cycle, 0006106=fumarate metabolic process" "0045239=tricarboxylic acid cycle enzyme complex, 0005739=mitochondrion, 0005737=cytoplasm" "IPR008948=L-Aspartase-like, IPR018951=Fumarase C, C-terminal, IPR005677=Fumarate hydratase, class II, IPR000362=Fumarate lyase family, IPR020557=Fumarate lyase, conserved site, IPR022761=Fumarate lyase, N-terminal, IPR024083=Fumarase/histidase, N-terminal" CG4095 16-Dec-15 2015_12 ENSDARG00000068620 YPL262W(FUM1) WBGene00001503(fum-1) ENSXETG00000006529(FH) ENSMUSG00000026526(Fh1) ENSG00000091483(FH) viable FBgn0260361 GSd431 http://flybase.net/reports/FBgn0260361.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0010411 RpS18 Ribosomal protein S18 http://flybase.net/reports/FBgn0010411.html "FBgn0014916, FBgn0025222, FBgn0062939" protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" "0006412=translation, 0000022=mitotic spindle elongation, 0006413=translational initiation, 0042254=ribosome biogenesis, 0007052=mitotic spindle organization" "0005730=nucleolus, 0005840=ribosome, 0022627=cytosolic small ribosomal subunit, 0000228=nuclear chromosome, 0015935=small ribosomal subunit, 0005737=cytoplasm, 0005829=cytosol" "rpS18, S18, BcDNA:RH43343, anon-fast-evolving-2D3, anon-EST:Posey27, M(2)56F, CG8900, transcription unit B, Rps18, B, RS18_DROME, unnamed, anon-56Fa, anon-EST:fe2D3" "IPR001892=Ribosomal protein S13, IPR018269=Ribosomal protein S13, conserved site, IPR010979=Ribosomal protein S13-like, H2TH, IPR027437=30s ribosomal protein S13, C-terminal" CG8900 16-Dec-15 2015_12 ENSDARG00000020153(rps18) "YDR450W(RPS18A),YML026C(RPS18B)" WBGene00004487(rps-18) ENSXETG00000020394(RPS18) "ENSMUSG00000008668(Rps18),ENSMUSG00000061330(Gm11361),ENSMUSG00000069117(Gm10260)" "ENSG00000096150,ENSG00000182498,ENSG00000206212" embryonic stage -- adult stage "lethal,viable,female fertile,female sterile" DRSC07540 IEK -1.688397032 -1.147814398 -2.981956834 -3.962467269 1.842357222 4.272608323 FBgn0014899 anon-10Af anon-10Af http://flybase.net/reports/FBgn0014899.html gene unnamed 16-Dec-15 2015_12 FBgn0040568 CG12331 http://flybase.net/reports/FBgn0040568.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036102 CG12523 http://flybase.net/reports/FBgn0036102.html FBgn0062974 protein_coding_gene BcDNA:RE74758 CG12523 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC09895 K 0.047105887 -0.143025395 -0.00241957 0.091430416 3.05753048 1.03766784 FBgn0001556 l(1)19Ca lethal (1) 19Ca http://flybase.net/reports/FBgn0001556.html gene "17-457, 17-238" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0001797 l(1)Mb46 lethal (1) Mb46 http://flybase.net/reports/FBgn0001797.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031051 Ranbp21 Ranbp21 http://flybase.net/reports/FBgn0031051.html protein_coding_gene 0008536=Ran GTPase binding 0006886=intracellular protein transport "Exp-5, Exportin-5, RanBP21, Exportin 5, dmExp5, CG12234, Exp5" "IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical, IPR013598=Exportin-1/Importin-beta-like" CG12234 16-Dec-15 2015_12 ENSDARG00000002303(si:ch211-286m4.4) YDR335W(MSN5) ENSXETG00000010883() ENSMUSG00000067150(Xpo5) ENSG00000124571(XPO5) "viable,visible" trichogen cell FBgn0010133 l(1)tsW4 lethal (1) tsW4 http://flybase.net/reports/FBgn0010133.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0029580 CG14778 http://flybase.net/reports/FBgn0029580.html protein_coding_gene "0016021=integral component of membrane, 0005778=peroxisomal membrane" IPR007248=Mpv17/PMP22 CG14778 16-Dec-15 2015_12 YLR251W(SYM1) FBgn0039751 CG1983 http://flybase.net/reports/FBgn0039751.html protein_coding_gene 0030170=pyridoxal phosphate binding "IPR029066=PLP-binding barrel, IPR001608=Alanine racemase, N-terminal, IPR011078=Uncharacterised protein family UPF0001" CG1983 16-Dec-15 2015_12 ENSDARG00000060288(prosc) YBL036C() WBGene00017286(F09E5.8) ENSMUSG00000031485(Prosc) ENSG00000147471(PROSC) "viable,visible" trichogen cell FBgn0019815 eve::ftz::Mmus\En1 En1 http://flybase.net/reports/FBgn0019815.html engineered_fusion_gene eve::ftz::Mus\En1 16-Dec-15 2015_12 FBgn0032363 CG6509 http://flybase.net/reports/FBgn0032363.html protein_coding_gene "0007298=border follicle cell migration, 0046331=lateral inhibition, 0019730=antimicrobial humoral response" "LD32687, Dlg5, DLG5" "IPR001452=SH3 domain, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR001478=PDZ domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008144=Guanylate kinase-like domain" CG6509 16-Dec-15 2015_12 WBGene00009678(F44D12.1) ENSXETG00000018090(DLG5) ENSMUSG00000021782(Dlg5) ENSG00000151208(DLG5) "viable,visible" "border follicle cell,chaeta,supernumerary,mesothoracic tergum" DRSC02964 K -0.098174318 0.473062568 -0.917604602 0.780943502 0.622059393 1.846124625 FBgn0003424 slgB sluggish B http://flybase.net/reports/FBgn0003424.html gene 16-Dec-15 2015_12 "phototaxis defective,male,female,mating defective,courtship behavior defective,behavior defective" FBgn0001512 l(1)10Ff lethal (1) 10Ff http://flybase.net/reports/FBgn0001512.html gene 16-Dec-15 2015_12 lethal FBgn0040678 CG15586 http://flybase.net/reports/FBgn0040678.html protein_coding_gene 16-Dec-15 2015_12 FBgn0042133 CG18810 http://flybase.net/reports/FBgn0042133.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005794=Golgi apparatus "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG18810 16-Dec-15 2015_12 ENSDARG00000036364(zdhhc24) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) viable FBgn0082958 snoRNA:ë¬28S-3405c snoRNA:ë¬28S-3405c http://flybase.net/reports/FBgn0082958.html snoRNA_gene "psi28s-3405c, CR34621, chr3R:24427860..24427959" CR34621 16-Dec-15 2015_12 FBgn0030411 CG2540 http://flybase.net/reports/FBgn0030411.html protein_coding_gene "IPR006840=ChaC-like protein, IPR013024=Butirosin biosynthesis, BtrG-like" CG2540 16-Dec-15 2015_12 ENSDARG00000055078(chac2) YER163C() ENSMUSG00000020309(Chac2) ENSG00000143942(CHAC2) viable DRSC19856 K 0.370326627 0.461557943 0.378474815 0.286391636 -1.596268165 -0.210272847 FBgn0033543 CG12338 http://flybase.net/reports/FBgn0033543.html protein_coding_gene "0008445=D-aspartate oxidase activity, 0071949=FAD binding" "0055114=oxidation-reduction process, 0046416=D-amino acid metabolic process" 0005777=peroxisome "IPR023209=D-amino-acid oxidase, IPR006076=FAD dependent oxidoreductase, IPR006181=D-amino acid oxidase, conserved site" CG12338 16-Dec-15 2015_12 "ENSXETG00000021315(DDO),ENSXETG00000022308(DAO)" "ENSMUSG00000063428(Ddo),ENSMUSG00000042096(Dao)" "ENSG00000203797(DDO),ENSG00000110887(DAO)" "viable,fertile" FBgn0004756 l(3)89Bi lethal (3) 89Bi http://flybase.net/reports/FBgn0004756.html gene 16-Dec-15 2015_12 lethal FBgn0028071 l(3)S090001 lethal (3) S090001 http://flybase.net/reports/FBgn0028071.html gene 0900/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0005114 l(1)272-13 lethal (1) 272-13 http://flybase.net/reports/FBgn0005114.html gene 16-Dec-15 2015_12 lethal FBgn0035151 CG17129 http://flybase.net/reports/FBgn0035151.html protein_coding_gene CG17129 16-Dec-15 2015_12 "viable,fertile" FBgn0250862 CG42237 http://flybase.net/reports/FBgn0250862.html FBgn0003193 protein_coding_gene "0004623=phospholipase A2 activity, 0005509=calcium ion binding" "0006644=phospholipid metabolic process, 0016042=lipid catabolic process" "C133, CG4346, PLA2, phospholipase A2" "IPR001211=Phospholipase A2, IPR013090=Phospholipase A2, active site, IPR016090=Phospholipase A2 domain" CG42237 16-Dec-15 2015_12 viable FBgn0034371 SP2637 SP2637 http://flybase.net/reports/FBgn0034371.html FBgn0043808 protein_coding_gene "0008418=protein-N-terminal asparagine amidohydrolase activity, 0004067=asparaginase activity" "BEST:GH24992, CG5473, dm-ntan1" IPR026750=Protein N-terminal asparagine amidohydrolase CG5473 16-Dec-15 2015_12 ENSDARG00000042135(zgc:77869) ENSMUSG00000022681(Ntan1) ENSG00000157045(NTAN1) "viable,fertile" FBgn0020559 anon-XII-F3 anon-XII-F3 http://flybase.net/reports/FBgn0020559.html gene 16-Dec-15 2015_12 Bolwig nerve FBgn0014291 l(3)64Bb lethal (3) 64Bb http://flybase.net/reports/FBgn0014291.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263985 CR43734 http://flybase.net/reports/FBgn0263985.html pseudogene_attribute CR43734 16-Dec-15 2015_12 FBgn0261731 EC2364 http://flybase.net/reports/FBgn0261731.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0262848 CR43212 http://flybase.net/reports/FBgn0262848.html pseudogene_attribute "noncoding_23159, noncoding_23161" CR43212 16-Dec-15 2015_12 FBgn0082348 HM415 HM415 http://flybase.net/reports/FBgn0082348.html gene 16-Dec-15 2015_12 FBgn0011479 l(3)neo46 lethal (3) neo46 http://flybase.net/reports/FBgn0011479.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261628 CG42711 http://flybase.net/reports/FBgn0261628.html protein_coding_gene CG42711 16-Dec-15 2015_12 FBgn0267552 CR45892 http://flybase.net/reports/FBgn0267552.html non_protein_coding_gene CR45892 16-Dec-15 2015_12 FBgn0259368 EP-575 http://flybase.net/reports/FBgn0259368.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0260076 2L4744 http://flybase.net/reports/FBgn0260076.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0002884 mus109 mutagen-sensitive 109 http://flybase.net/reports/FBgn0002884.html gene "mus-109, mus(1)109, l(1)9Aa, mus107, l(1)19-65, mus(1)107" 16-Dec-15 2015_12 "chemical sensitive,mitotic cell cycle defective,recessive,lethal,radiation sensitive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "mitosis & nuclear chromosome,imaginal disc,cell cycle" FBgn0052493 tRNA:CR32493 transfer RNA:CR32493 http://flybase.net/reports/FBgn0052493.html FBgn0060101 tRNA_gene 0033427=CAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:Q:TTG:AE002566, chrX.trna26-GlnTTG, AE002566.trna6-GlnTTG, CR32493" CR32493 16-Dec-15 2015_12 FBgn0034464 CG11018 http://flybase.net/reports/FBgn0034464.html FBgn0044761 protein_coding_gene anon-WO0140519.121 CG11018 16-Dec-15 2015_12 viable DRSC28771 K -0.146720555 0.278794802 0.192827345 -0.530770145 -1.627485798 0.085867644 FBgn0002251 l(3)68Ec lethal (3) 68Ec http://flybase.net/reports/FBgn0002251.html gene "rose-gespleten region interval 13, l(3)rsg13, rsg13" 16-Dec-15 2015_12 lethal FBgn0044127 E(rst)B203 E(rst)B203 http://flybase.net/reports/FBgn0044127.html gene 0001745=compound eye morphogenesis B203 16-Dec-15 2015_12 viable "eye,cone cell,secondary pigment cell,ectopic,tertiary pigment cell" FBgn0002619 M(3)82BC Minute (3) 82BC http://flybase.net/reports/FBgn0002619.html gene "M, M(3)S39, Minute" 16-Dec-15 2015_12 "Minute,dominant,visible" macrochaeta FBgn0277420 l(3)psg23 http://flybase.net/reports/FBgn0277420.html gene psg23 16-Dec-15 2015_12 FBgn0002669 mat(2)ea-F maternal effect early arrest F http://flybase.net/reports/FBgn0002669.html gene "mat(2)earlyRL4, early-RL4" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0016676 Mab11B5 Monoclonal antibody 11B5 http://flybase.net/reports/FBgn0016676.html gene 16-Dec-15 2015_12 FBgn0266649 CR45156 http://flybase.net/reports/FBgn0266649.html non_protein_coding_gene CR45156 16-Dec-15 2015_12 FBgn0033061 CG14590 http://flybase.net/reports/FBgn0033061.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression "IPR002893=Zinc finger, MYND-type, IPR001214=SET domain" CG14590 16-Dec-15 2015_12 viable FBgn0022758 Wmc4 Wee-Mik-Complementing 4 http://flybase.net/reports/FBgn0022758.html gene WMC4 16-Dec-15 2015_12 FBgn0061046 l(3)S023634 lethal (3) S023634 http://flybase.net/reports/FBgn0061046.html gene 0236/34 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0002846 msd(gl) modifier of sexual dimorphism of glass http://flybase.net/reports/FBgn0002846.html gene 16-Dec-15 2015_12 FBgn0259546 B0472 http://flybase.net/reports/FBgn0259546.html gene 16-Dec-15 2015_12 visible "tarsal segment,leg,unguis,wing,arista,mesothoracic tergum" FBgn0065498 l(2)SH1214 lethal (2) SH1214 http://flybase.net/reports/FBgn0065498.html gene l(2)SH2 1214 16-Dec-15 2015_12 "lethal,recessive" FBgn0032169 CG4709 http://flybase.net/reports/FBgn0032169.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR000571=Zinc finger, CCCH-type, IPR000467=G-patch domain" CG4709 16-Dec-15 2015_12 ENSDARG00000027403(zgpat) WBGene00016383(C33H5.17) ENSMUSG00000027582(Zgpat) ENSG00000197114(ZGPAT) viable FBgn0259123 ponchik ponchik http://flybase.net/reports/FBgn0259123.html gene 16-Dec-15 2015_12 FBgn0086032 snoRNA:Me28S-C437 http://flybase.net/reports/FBgn0086032.html snoRNA_gene "Me28S-Cm437, CR34661" CR34661 16-Dec-15 2015_12 FBgn0013600 l(3)B48.1M3 lethal (3) B48.1M3 http://flybase.net/reports/FBgn0013600.html gene 16-Dec-15 2015_12 lethal FBgn0003643 Su(y3P) Suppressor of yellow-P http://flybase.net/reports/FBgn0003643.html gene "su-y[31e], Suppressor of yellow-3 of Patterson" 16-Dec-15 2015_12 FBgn0063928 GS2035 GS2035 http://flybase.net/reports/FBgn0063928.html gene 16-Dec-15 2015_12 long lived FBgn0065568 l(2)SH0973 lethal (2) SH0973 http://flybase.net/reports/FBgn0065568.html gene l(2)SH2 0973 16-Dec-15 2015_12 "lethal,recessive" FBgn0263623 CR43632 http://flybase.net/reports/FBgn0263623.html non_protein_coding_gene CR43632 16-Dec-15 2015_12 FBgn0020223 Chr1 Chloroform resistant 1 http://flybase.net/reports/FBgn0020223.html gene unnamed 16-Dec-15 2015_12 "chemical resistant,dominant" FBgn0033124 Tsp42Ec Tetraspanin 42Ec http://flybase.net/reports/FBgn0033124.html protein_coding_gene 0016021=integral component of membrane "tetraspanin 42E, Dm.Tsp42Ec, CG12847" "IPR000301=Tetraspanin, IPR018499=Tetraspanin/Peripherin, IPR008952=Tetraspanin, EC2 domain" CG12847 16-Dec-15 2015_12 viable FBgn0036212 CG11597 http://flybase.net/reports/FBgn0036212.html protein_coding_gene 0004722=protein serine/threonine phosphatase activity "0046331=lateral inhibition, 0070262=peptidyl-serine dephosphorylation, 0006470=protein dephosphorylation" "0005634=nucleus, 0005737=cytoplasm, 0000159=protein phosphatase type 2A complex" "PP4-like, PP4" "IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase" CG11597 16-Dec-15 2015_12 "viable,visible" "chaeta,trichogen cell" FBgn0003274 RpLP2 Ribosomal protein LP2 http://flybase.net/reports/FBgn0003274.html "FBgn0003736, FBgn0062859" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0006414=translational elongation" "0022625=cytosolic large ribosomal subunit, 0022626=cytosolic ribosome, 0005840=ribosome" "Temporal-protein-1, rpA1, bs34h02.y1, Ribosomal protein P1, Tp1, chr2R:12101099..12101299, RpP1, ACIDIC RIBOSOMAL PROTEIN LP2, CG4918, Ribosomal protein A1, BcDNA:SD22208, LP2, T1, RpA1, Temporal protein 1, RplP2, RLA2_DROME" IPR027534=Ribosomal protein L12 family CG4918 16-Dec-15 2015_12 "ENSDARG00000011201(rplp2l),ENSDARG00000022833(rplp2)" "YDR382W(RPP2B),YOL039W(RPP2A)" "WBGene00004410(rla-2),WBGene00016493(C37A2.7)" ENSXETG00000019024(rplp2) ENSMUSG00000025508(Rplp2) ENSG00000177600(RPLP2) viable DRSC07539 IEK -1.768852739 -1.733591978 -4.094998839 -5.591663459 -0.22835269 1.966046873 FBgn0013710 mt:tRNA:Y mitochondrial tyrosine tRNA http://flybase.net/reports/FBgn0013710.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006297, CR34066, tRNA[Tyr], tRNAtyr" CR34066 16-Dec-15 2015_12 FBgn0003196 Raf-oncogene-2 Raf oncogene 2 http://flybase.net/reports/FBgn0003196.html gene "raf2, Raf2, Draf-2" 16-Dec-15 2015_12 FBgn0023435 jew jewel http://flybase.net/reports/FBgn0023435.html gene 16-Dec-15 2015_12 visible pigment cell FBgn0037195 CG11226 http://flybase.net/reports/FBgn0037195.html FBgn0063728 protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis BcDNA:AT16729 CG11226 16-Dec-15 2015_12 "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0065465 l(2)SH1344 lethal (2) SH1344 http://flybase.net/reports/FBgn0065465.html gene l(2)SH2 1344 16-Dec-15 2015_12 "lethal,recessive" FBgn0060291 snoRNA:U49:66Db snoRNA:U49:66Db http://flybase.net/reports/FBgn0060291.html snoRNA_gene "Dmel\U49b, Me28S-C3341(U49), CR32910, U49b" CR32910 16-Dec-15 2015_12 FBgn0262994 CR43302 http://flybase.net/reports/FBgn0262994.html non_protein_coding_gene CR43302 16-Dec-15 2015_12 FBgn0035970 CG4483 http://flybase.net/reports/FBgn0035970.html protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0008270=zinc ion binding" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase, IPR001452=SH3 domain" CG4483 16-Dec-15 2015_12 WBGene00010892(M18.8) ENSXETG00000018774(ZDHHC6) ENSMUSG00000024982(Zdhhc6) ENSG00000023041(ZDHHC6) viable FBgn0039758 CG9737 http://flybase.net/reports/FBgn0039758.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006909=phagocytosis, 0006508=proteolysis" "SP5, c-SP5" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR022700=Proteinase, regulatory CLIP domain, IPR006604=Disulphide knot CLIP" CG9737 16-Dec-15 2015_12 viable FBgn0259607 B1116 http://flybase.net/reports/FBgn0259607.html gene 16-Dec-15 2015_12 visible "tarsal segment,proboscis" FBgn0005281 M(3)d Minute (3) d http://flybase.net/reports/FBgn0005281.html gene 16-Dec-15 2015_12 FBgn0020542 l(1)18DEc lethal (1) 18DEc http://flybase.net/reports/FBgn0020542.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023511 Edem1 "ER degradation enhancer, mannosidase alpha-like 1" http://flybase.net/reports/FBgn0023511.html protein_coding_gene "0005509=calcium ion binding, 0004571=mannosyl-oligosaccharide 1,2-alpha-mannosidase activity" "0030433=ER-associated ubiquitin-dependent protein catabolic process, 0008340=determination of adult lifespan, 0030968=endoplasmic reticulum unfolded protein response" 0016020=membrane "EDEM1, DM-pI, Edem1, EG:86E4.2, EG.86E4.2, edem1, CG3810" "IPR001382=Glycoside hydrolase, family 47" CG3810 16-Dec-15 2015_12 YHR204W(MNL1) ENSXETG00000007449(BC076880.1) ENSMUSG00000038312(Edem2) ENSG00000088298(EDEM2) "viable,long lived,dominant,partially lethal - majority die,some die during pharate adult stage" FBgn0005764 l(1)TK411 lethal (1) TK411 http://flybase.net/reports/FBgn0005764.html gene l411 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0032701 CG10341 http://flybase.net/reports/FBgn0032701.html protein_coding_gene 0003723=RNA binding "0001522=pseudouridine synthesis, 0042254=ribosome biogenesis, 0022008=neurogenesis" 0005732=small nucleolar ribonucleoprotein complex "IPR007504=H/ACA ribonucleoprotein complex, subunit Gar1/Naf1, IPR009000=Translation protein, beta-barrel domain" CG10341 16-Dec-15 2015_12 ENSDARG00000057929(si:dkey-22l11.5) WBGene00009132(F25H8.2) ENSMUSG00000014907 ENSG00000145414(NAF1) "lethal,neuroanatomy defective" ganglion mother cell FBgn0260587 2L2436 http://flybase.net/reports/FBgn0260587.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0040738 CG14504 http://flybase.net/reports/FBgn0040738.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085793 CR41510 http://flybase.net/reports/FBgn0085793.html FBan0041510 non_protein_coding_gene 16-Dec-15 2015_12 FBgn0000988 mama maternal metaphase arrest http://flybase.net/reports/FBgn0000988.html gene "maternal(2)late oogenesis-DF6, mat(2)lto-DF6, fs(2)ltoDF6, fs(2)lo-A, fs(2)lto5, female sterile(2)lto5" 16-Dec-15 2015_12 "lethal,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,female sterile,mitotic cell cycle defective,male fertile,reduced" "oocyte,maternal effect,adult fat body,yolk,adult corpus allatum,pre-blastoderm embryo,female" FBgn0001405 l(1)3Ag lethal (1) 3Ag http://flybase.net/reports/FBgn0001405.html gene 0003729=mRNA binding "l(1)zw13, zw-13, ZW-13, zw13, zeste-white 13" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" female reproductive system FBgn0014127 barr barren http://flybase.net/reports/FBgn0014127.html protein_coding_gene "0003682=chromatin binding, 0072587=DNA topoisomerase (ATP-hydrolyzing) activator activity, 0044547=DNA topoisomerase binding, 0005515=protein binding" "0048567=ectodermal digestive tract morphogenesis, 0002009=morphogenesis of an epithelium, 0006099=tricarboxylic acid cycle, 0007424=open tracheal system development, 0007443=Malpighian tubule morphogenesis, 0016458=gene silencing, 0000070=mitotic sister chromatid segregation, 0007076=mitotic chromosome condensation, 0022008=neurogenesis, 0008258=head involution, 0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0007067=mitotic nuclear division, 0051306=mitotic sister chromatid separation" "0005634=nucleus, 0000793=condensed chromosome, 0000785=chromatin, 0000775=chromosome, centromeric region, 0000796=condensin complex" "Barr, CapH, Barren, barren, Cap-H, CAP-H, CG10726, dCap-H, CG14684, 38B.3" IPR022816=Condensin complex subunit 2/barren CG10726 16-Dec-15 2015_12 ENSDARG00000061468(ncaph) YBL097W(BRN1) ENSXETG00000001245(brrn1) ENSMUSG00000034906(Ncaph) ENSG00000121152(NCAPH) embryonic stage | early

ubiquitous "viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,suppressor of variegation,dominant,enhancer of variegation,non-enhancer of variegation,partially,wild-type,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "peripheral nervous system,neuron,presumptive embryonic/larval peripheral nervous system,multidendritic neuron,chordotonal organ,lateral,embryonic Malpighian tubule,embryonic/larval proventriculus,midgut constriction,embryonic head,embryonic/larval trachea,embryonic epidermis,embryonic/larval pharynx,mitotic cell cycle,chromosome,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell" DRSC03488 IE 2.922058063 0.268740856 2.419523358 -0.498801451 0.714604813 0.591708005 FBgn0039626 Slu7 Slu7 http://flybase.net/reports/FBgn0039626.html protein_coding_gene "0008270=zinc ion binding, 0030628=pre-mRNA 3'-splice site binding" "0007052=mitotic spindle organization, 0000398=mRNA splicing, via spliceosome, 0000389=mRNA 3'-splice site recognition" "0005681=spliceosomal complex, 0016607=nuclear speck" "SLU7, CG1420" "IPR021715=Pre-mRNA splicing Prp18-interacting factor, IPR001878=Zinc finger, CCHC-type" CG1420 16-Dec-15 2015_12 ENSDARG00000038870(slu7) ENSXETG00000016536(TGas066l21.1) ENSMUSG00000020409(Slu7) ENSG00000164609(SLU7) lethal FBgn0051908 CG31908 http://flybase.net/reports/FBgn0051908.html FBgn0063616 protein_coding_gene CG8761 "IPR024642=SUZ-C domain, IPR024771=SUZ domain" CG31908 16-Dec-15 2015_12 FBgn0070010 BG01353 BG01353 http://flybase.net/reports/FBgn0070010.html gene 16-Dec-15 2015_12 stress response defective FBgn0039507 mrt martik http://flybase.net/reports/FBgn0039507.html protein_coding_gene "0008355=olfactory learning, 0007611=learning or memory" "Martik, CG3361" CG3361 16-Dec-15 2015_12 "memory defective,viable,fertile" FBgn0085624 CG41339 http://flybase.net/reports/FBgn0085624.html FBan0041339 protein_coding_gene 16-Dec-15 2015_12 FBgn0029752 TrxT Thioredoxin T http://flybase.net/reports/FBgn0029752.html protein_coding_gene "0015036=disulfide oxidoreductase activity, 0016491=oxidoreductase activity, 0015035=protein disulfide oxidoreductase activity" "0045454=cell redox homeostasis, 0006457=protein folding, 0006662=glycerol ether metabolic process, 0006974=cellular response to DNA damage stimulus" "0000806=Y chromosome, 0005634=nucleus" "DmTrxT, CG3315, 3315, thioredoxin, ThioredoxinT, DmelTrxT" "IPR013766=Thioredoxin domain, IPR017937=Thioredoxin, conserved site, IPR012336=Thioredoxin-like fold, IPR005746=Thioredoxin" CG3315 16-Dec-15 2015_12 "ENSDARG00000044125(zgc:92903),ENSDARG00000031435(zgc:56493)" "YGR209C(TRX2),YLR043C(TRX1)" WBGene00015062(trx-1) "ENSXETG00000002592(txn),ENSXETG00000010267()" ENSMUSG00000028367(Txn1) ENSG00000136810(TXN) "chemical resistant,long lived,viable" FBgn0024851 mus113 mus113 http://flybase.net/reports/FBgn0024851.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0025882 snoRNA:MeU6-A47 snoRNA:MeU6-A47 http://flybase.net/reports/FBgn0025882.html FBgn0052519 snoRNA_gene 0005730=nucleolus "CR32519, Z30 small nucleolar RNA, snoRNA:Z30, mgU6-47, MeU6-A47(Z30), chrX:21197545..21197641, mgU6-47 snoRNA" CR32519 16-Dec-15 2015_12 FBgn0003521 stb short bristle http://flybase.net/reports/FBgn0003521.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile" macrochaeta FBgn0267158 CR45598 http://flybase.net/reports/FBgn0267158.html non_protein_coding_gene CR45598 16-Dec-15 2015_12 FBgn0060867 l(3)S047214 lethal (3) S047214 http://flybase.net/reports/FBgn0060867.html gene 0472/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0261380 mRpL37 mitochondrial ribosomal protein L37 http://flybase.net/reports/FBgn0261380.html "FBgn0037833, FBgn0261355" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "mRpL2a, MRP-L2, MRpL37, CG6547, mitochondrial ribosomal protein L2a, CG42632" IPR010793=Ribosomal protein L37/S30 CG42632 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0005718 l(1)TK125 lethal (1) TK125 http://flybase.net/reports/FBgn0005718.html gene l125 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0014011 Rac2 Rac2 http://flybase.net/reports/FBgn0014011.html protein_coding_gene "0005525=GTP binding, 0019901=protein kinase binding, 0003924=GTPase activity" "0090303=positive regulation of wound healing, 0008104=protein localization, 0006909=phagocytosis, 0034334=adherens junction maintenance, 0007435=salivary gland morphogenesis, 0030032=lamellipodium assembly, 0002009=morphogenesis of an epithelium, 0051017=actin filament bundle assembly, 0010883=regulation of lipid storage, 0050770=regulation of axonogenesis, 0007390=germ-band shortening, 0002118=aggressive behavior, 0007520=myoblast fusion, 0000902=cell morphogenesis, 0035011=melanotic encapsulation of foreign target, 0007266=Rho protein signal transduction, 0008103=oocyte microtubule cytoskeleton polarization, 0042052=rhabdomere development, 0046331=lateral inhibition, 0035099=hemocyte migration, 0042742=defense response to bacterium, 0007254=JNK cascade, 0007424=open tracheal system development, 0002433=immune response-regulating cell surface receptor signaling pathway involved in phagocytosis, 0008258=head involution, 0007391=dorsal closure, 0045451=pole plasm oskar mRNA localization, 0035010=encapsulation of foreign target, 0046843=dorsal appendage formation, 0016203=muscle attachment, 0007631=feeding behavior, 0031532=actin cytoskeleton reorganization, 0007394=dorsal closure, elongation of leading edge cells, 0007617=mating behavior, 0007426=tracheal outgrowth, open tracheal system" 0005622=intracellular "DmRAC2, Rac1, Drac1b, Rac1b, rac2, RacB, DRac2, DRacB, D-Rac2, P48554, Rac-2, Rac, Drac2, D-Rac 2, Rac GTPase, CG8556" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type" CG8556 16-Dec-15 2015_12 "ENSDARG00000030947,ENSDARG00000002951,ENSDARG00000020795(zgc:175209),ENSDARG00000040651(rac3)" "WBGene00000424(ced-10),WBGene00004287(rac-2)" "ENSXETG00000027593(Rac1),ENSXETG00000004629(BC087999.1)" "ENSMUSG00000018012(Rac3),ENSMUSG00000001847(Rac1)" "ENSG00000169750(RAC3),ENSG00000128340(RAC2),ENSG00000136238(RAC1)" " embryonic stage | pre-blastoderm , embryonic stage | stage 12-13 , embryonic stage , embryonic stage | stage 5-6 , embryonic stage | >stage 13 , embryonic stage | stage 11-13 , embryonic stage -- adult stage " " organism | ubiquitous

, visceral mesoderm

, organism | pair rule

,

ubiquitous , head mesoderm

, somatic mesoderm

" "visible,immune response defective,viable,neuroanatomy defective,feeding behavior defective,short lived,long lived,recessive,behavior defective,male limited,locomotor behavior defective,courtship behavior defective,neurophysiology defective,male fertile,cell shape defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "embryonic somatic muscle,embryonic pericardial cell,eye,ommatidium,wing,wing vein,mesoderm,embryonic myoblast,muscle founder cell,supernumerary,pericardial cell,peripheral glial cell,serotonergic neuron,plasmatocyte,lamellocyte,embryonic/larval hemocyte,retina,photoreceptor,pigment cell,chaeta,dorsal appendage,posterior" DRSC11262 I -0.146412449 -2.529934619 -0.305536688 -0.693342144 -0.593383139 0.239970457 FBgn0259846 Su(Ste):CR42415 Su(Ste):CR42415 http://flybase.net/reports/FBgn0259846.html non_protein_coding_gene CR42415 CR42415 16-Dec-15 2015_12 FBgn0063491 GstE9 Glutathione S transferase E9 http://flybase.net/reports/FBgn0063491.html FBgn0034343 protein_coding_gene 0004364=glutathione transferase activity "0006749=glutathione metabolic process, 0009636=response to toxic substance" 0005737=cytoplasm "GST3-1, CG17534, GSTE9, Gst3-1, E9, gste9, Glutathion S-transferase, DmGSTE9, CT38753" "IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal" CG17534 16-Dec-15 2015_12 YLL060C(GTT2) viable FBgn0069306 X-72-7 X-72-7 http://flybase.net/reports/FBgn0069306.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0027779 VhaSFD Vacuolar H+-ATPase SFD subunit http://flybase.net/reports/FBgn0027779.html protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" "0033227=dsRNA transport, 0015991=ATP hydrolysis coupled proton transport, 0008340=determination of adult lifespan" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0005886=plasma membrane, 0033181=plasma membrane proton-transporting V-type ATPase complex" "V1 H subunit, vhaSFD, V-ATPase subunit H, Vacuolar H+-ATPase SFD subunit, V-ATPase H-subunit, V-ATPase, ATP6V1H, CG17332, 144191_at" "IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR004908=ATPase, V1 complex, subunit H, IPR011987=ATPase, V1 complex, subunit H, C-terminal" CG17332 16-Dec-15 2015_12 ENSDARG00000006370(atp6v1h) YPR036W(VMA13) WBGene00020507(vha-15) ENSXETG00000008095(ATP6V1H) ENSMUSG00000033793(Atp6v1h) ENSG00000047249(ATP6V1H) "viable,size defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,long lived,lethal - all die before end of pupal stage,some die during pupal stage" "eye disc,somatic clone,multivesicular body | larval stage | somatic clone,Malpighian tubule" FBgn0023068 l(1)20Ai lethal (1) 20Ai http://flybase.net/reports/FBgn0023068.html gene C2/44.1 16-Dec-15 2015_12 "lethal,recessive" FBgn0002559 lot lot http://flybase.net/reports/FBgn0002559.html gene lot-235 16-Dec-15 2015_12 FBgn0267032 CR45476 http://flybase.net/reports/FBgn0267032.html non_protein_coding_gene CR45476 16-Dec-15 2015_12 FBgn0003920 snRNA:U2:14B small nuclear RNA U2 at 14B http://flybase.net/reports/FBgn0003920.html FBgn0003919 snRNA_gene "0000398=mRNA splicing, via spliceosome" "0015030=Cajal body, 0005686=U2 snRNP" "U2 snRNA, CR32913, K6, U2-14B, dU2, U2snRNA14B, U2, snRNA:U2, U2:14B, 14B U2, small nuclear RNA U2, U2snRNA" CR32913 16-Dec-15 2015_12 FBgn0038371 Pbp45 PSEA-binding protein 45kD http://flybase.net/reports/FBgn0038371.html FBgn0022383 protein_coding_gene "0005515=protein binding, 0003677=DNA binding, 0003681=bent DNA binding, 0043565=sequence-specific DNA binding" "0042795=snRNA transcription from RNA polymerase II promoter, 0042796=snRNA transcription from RNA polymerase III promoter, 0065004=protein-DNA complex assembly" 0019185=snRNA-activating protein complex "DmPBP45, DmSNAPc, DmPBP, Drosophila melanogaster PSE-binding protein 45-kDa subunit, CG9597, SNAP43, PSEA-binding protein, DmSNAP43" "IPR019188=Small nuclear RNA activating complex (SNAPc), subunit SNAP43" CG9597 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0060757 l(3)S063818 lethal (3) S063818 http://flybase.net/reports/FBgn0060757.html gene 0638/18 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0065658 l(2)SH0718 lethal (2) SH0718 http://flybase.net/reports/FBgn0065658.html gene l(2)SH2 0718 16-Dec-15 2015_12 "lethal,recessive" FBgn0262612 CG43138 http://flybase.net/reports/FBgn0262612.html protein_coding_gene CG43138 16-Dec-15 2015_12 FBgn0002553 lix little isoxanthopterin http://flybase.net/reports/FBgn0002553.html gene 0004154=dihydropterin oxidase activity 16-Dec-15 2015_12 wild-type testis pigment cell FBgn0065284 l(2)SH2023 lethal (2) SH2023 http://flybase.net/reports/FBgn0065284.html gene l(2)SH2 2023 16-Dec-15 2015_12 "lethal,recessive" FBgn0065159 l(3)SH045 lethal (3) SH045 http://flybase.net/reports/FBgn0065159.html gene l(2)SH3 045 16-Dec-15 2015_12 "lethal,recessive" FBgn0020357 anon-28Cf anon-28Cf http://flybase.net/reports/FBgn0020357.html gene 538 16-Dec-15 2015_12 FBgn0016777 anon-77Ba anon-77Ba http://flybase.net/reports/FBgn0016777.html gene "transcript A, A" 16-Dec-15 2015_12 FBgn0032193 CG5727 http://flybase.net/reports/FBgn0032193.html FBgn0063170 protein_coding_gene BcDNA:LD02427 CG5727 16-Dec-15 2015_12 viable FBgn0003556 su(dx)r "suppressor of deltex, recessive" http://flybase.net/reports/FBgn0003556.html gene "su[X]-dx, suppressor of deltex, suppressor in X chromosome of deltex, su(dx)" 16-Dec-15 2015_12 FBgn0060934 l(3)S041405 lethal (3) S041405 http://flybase.net/reports/FBgn0060934.html gene 0414/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266124 ghi ghiberti http://flybase.net/reports/FBgn0266124.html "FBgn0083090, FBgn0052038" protein_coding_gene 0004758=serine C-palmitoyltransferase activity "0000916=actomyosin contractile ring contraction, 0007111=meiosis II cytokinesis, 0043147=meiotic spindle stabilization, 0030148=sphingolipid biosynthetic process, 0007110=meiosis I cytokinesis, 0007476=imaginal disc-derived wing morphogenesis" 0017059=serine C-palmitoyltransferase complex "CG32038, fro, frodo" CG32038 16-Dec-15 2015_12 FBgn0029710 CG3568 http://flybase.net/reports/FBgn0029710.html protein_coding_gene CG3568 16-Dec-15 2015_12 viable FBgn0005156 l(2)G121 lethal (2) G121 http://flybase.net/reports/FBgn0005156.html gene 16-Dec-15 2015_12 lethal FBgn0042129 OS9 Olfactory-specific 9 http://flybase.net/reports/FBgn0042129.html protein_coding_gene 0007608=sensory perception of smell 0005634=nucleus "OS9, CG18806" CG18806 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264648 ivy ivy http://flybase.net/reports/FBgn0264648.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0259648 B1022 http://flybase.net/reports/FBgn0259648.html gene 16-Dec-15 2015_12 visible "submarginal cell,wing vein,anterior crossvein" FBgn0023117 anon-10Aq anon-10Aq http://flybase.net/reports/FBgn0023117.html gene 9 16-Dec-15 2015_12 FBgn0051637 CG31637 http://flybase.net/reports/FBgn0051637.html "FBgn0031827, FBgn0031828, FBgn0062239" protein_coding_gene 0008146=sulfotransferase activity "CG13765, anon-WO0118547.107, CG9551, d6ST1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000863=Sulfotransferase domain" CG31637 16-Dec-15 2015_12 "ENSDARG00000058071(LOC100002270),ENSDARG00000070640,ENSDARG00000061070(LOC559721),ENSDARG00000061357(zgc:194879),ENSDARG00000044341(LOC563748)" "ENSXETG00000019025(TNeu013b01.1),ENSXETG00000001015(CHST1),ENSXETG00000014798(),ENSXETG00000003576(),ENSXETG00000022131(chst2),ENSXETG00000004136(CHST7)" "ENSMUSG00000035930(Chst4),ENSMUSG00000031952(Chst5),ENSMUSG00000037347(Chst7),ENSMUSG00000033350(Chst2),ENSMUSG00000057337(Chst3),ENSMUSG00000027221(Chst1)" "ENSG00000140835(CHST4),ENSG00000183196(CHST6),ENSG00000135702(CHST5),ENSG00000147119(CHST7),ENSG00000175040(CHST2),ENSG00000175264(CHST1),ENSG00000122863(CHST3)" "viable,visible" trichogen cell DRSC03263 E -0.510386318 1.233864253 1.894499972 -0.401475802 -0.328418541 -0.165569235 FBgn0031320 CG5126 http://flybase.net/reports/FBgn0031320.html protein_coding_gene "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG5126 16-Dec-15 2015_12 "viable,fertile" FBgn0040382 CG5273 http://flybase.net/reports/FBgn0040382.html FBgn0029534 protein_coding_gene 0042752=regulation of circadian rhythm EG:BACR19J1.3 CG5273 16-Dec-15 2015_12 "viable,fertile,locomotor rhythm defective" FBgn0032609 CG13280 http://flybase.net/reports/FBgn0032609.html protein_coding_gene 0016491=oxidoreductase activity "IPR016040=NAD(P)-binding domain, IPR000683=Oxidoreductase, N-terminal" CG13280 16-Dec-15 2015_12 YML051W(GAL80) FBgn0261506 CG42654 http://flybase.net/reports/FBgn0261506.html protein_coding_gene CG42654 16-Dec-15 2015_12 FBgn0021769 nori-6 nori-6 http://flybase.net/reports/FBgn0021769.html gene 16-Dec-15 2015_12 "paralytic,heat sensitive" FBgn0037792 TAF1B TATA box-binding protein-associated factor RNA polymerase I subunit B http://flybase.net/reports/FBgn0037792.html protein_coding_gene "0001164=RNA polymerase I CORE element sequence-specific DNA binding, 0001187=RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity" "1901838=positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter, 0001189=RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript" "0005668=RNA polymerase transcription factor SL1 complex, 0005730=nucleolus" CG6241 IPR021752=Transcription initiation factor Rrn7 CG6241 16-Dec-15 2015_12 ENSDARG00000028937(taf1b) ENSXETG00000007011(TAF1B) ENSG00000115750(TAF1B) FBgn0060493 l(3)S108408c lethal (3) S108408c http://flybase.net/reports/FBgn0060493.html gene 1084/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0033292 Cyp4ad1 Cyp4ad1 http://flybase.net/reports/FBgn0033292.html FBgn0040498 protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "4ad1, cytochrome P450, CYP4-related, CG2110, BEST:LD02646" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG2110 16-Dec-15 2015_12 YMR015C(ERG5) FBgn0267468 CR45818 http://flybase.net/reports/FBgn0267468.html non_protein_coding_gene CR45818 16-Dec-15 2015_12 FBgn0085282 CG34253 http://flybase.net/reports/FBgn0085282.html protein_coding_gene CG32194 CG34253 16-Dec-15 2015_12 FBgn0265656 CR44463 http://flybase.net/reports/FBgn0265656.html non_protein_coding_gene lincRNA.315 CR44463 16-Dec-15 2015_12 FBgn0000375 crooked-setae crooked setae http://flybase.net/reports/FBgn0000375.html gene crk 16-Dec-15 2015_12 "visible,recessive,viable,fertile" "macrochaeta,acrostichal bristle,tergite,scutellar bristle,microchaeta & adult thorax,microchaeta & adult abdomen | female,female" FBgn0265585 CR44412 http://flybase.net/reports/FBgn0265585.html non_protein_coding_gene CR44412 16-Dec-15 2015_12 FBgn0060675 l(3)S077513b lethal (3) S077513b http://flybase.net/reports/FBgn0060675.html gene 0775/13 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000655 fi frail http://flybase.net/reports/FBgn0000655.html gene 16-Dec-15 2015_12 "visible,viable,reduced" "wing,macrochaeta" FBgn0013320 Pcp56 Pupal-cuticle-protein-56kD http://flybase.net/reports/FBgn0013320.html gene 16-Dec-15 2015_12 FBgn0036422 CG3868 http://flybase.net/reports/FBgn0036422.html protein_coding_gene 0005615=extracellular space CG3868 16-Dec-15 2015_12 "viable,fertile" FBgn0003526 sth small thin http://flybase.net/reports/FBgn0003526.html gene 16-Dec-15 2015_12 "female sterile,male fertile,viable,visible" "macrochaeta,adult abdomen,eye,wing" FBgn0005698 l(1)TK101 lethal (1) TK101 http://flybase.net/reports/FBgn0005698.html gene l101 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0028494 CG6424 http://flybase.net/reports/FBgn0028494.html "FBgn0045920, FBgn0045921, FBgn0045922, FBgn0061523" protein_coding_gene "anon-WO0153538.34, BcDNA:GH05095, anon-WO0153538.32, anon-WO0153538.33, anon-WO0118547.96, GH05095" CG6424 16-Dec-15 2015_12 "ENSXETG00000023661(FAM13A),ENSXETG00000003827(FAM13B)" "ENSMUSG00000037709(Fam13a),ENSMUSG00000036501(Fam13b),ENSMUSG00000043259(Fam13c)" viable FBgn0265629 CG44437 http://flybase.net/reports/FBgn0265629.html protein_coding_gene CG1903 CG44437 16-Dec-15 2015_12 FBgn0039771 Osi23 Osiris 23 http://flybase.net/reports/FBgn0039771.html protein_coding_gene 0005887=integral component of plasma membrane "CG15538, Osiris" IPR012464=Protein of unknown function DUF1676 CG15538 16-Dec-15 2015_12 viable FBgn0060447 l(3)S122211 lethal (3) S122211 http://flybase.net/reports/FBgn0060447.html gene 1222/11 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0043847 412\ORF3 ORF3 http://flybase.net/reports/FBgn0043847.html transposable_element_gene "0003676=nucleic acid binding, 0004190=aspartic-type endopeptidase activity" "0015074=DNA integration, 0006508=proteolysis" ORF3 "IPR021109=Aspartic peptidase domain, IPR001969=Aspartic peptidase, active site, IPR015416=Zinc finger, H2C2-type, histone UAS binding, IPR018061=Peptidase A2A, retrovirus RVP subgroup, IPR001995=Peptidase A2A, retrovirus, catalytic, IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain, IPR000477=Reverse transcriptase domain" 16-Dec-15 2015_12 FBgn0083030 snoRNA:ë¬18S-525i snoRNA:ë¬18S-525i http://flybase.net/reports/FBgn0083030.html snoRNA_gene "psi18S-525i, CR34584" CR34584 16-Dec-15 2015_12 FBgn0005452 l(1)v252 lethal (1) v252 http://flybase.net/reports/FBgn0005452.html gene l(1)252 16-Dec-15 2015_12 FBgn0039349 Ssadh Succinic semialdehyde dehydrogenase http://flybase.net/reports/FBgn0039349.html FBgn0062014 protein_coding_gene "0004777=succinate-semialdehyde dehydrogenase (NAD+) activity, 0009013=succinate-semialdehyde dehydrogenase [NAD(P)+] activity" "0055114=oxidation-reduction process, 0009450=gamma-aminobutyric acid catabolic process" 0005739=mitochondrion "anon-WO0118547.428, DmSSADH, SSADH, CG4685, succinic semialdehyde dehydrogenase" "IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR010102=Succinate semialdehyde dehydrogenase, IPR016163=Aldehyde dehydrogenase, C-terminal, IPR016161=Aldehyde/histidinol dehydrogenase, IPR015590=Aldehyde dehydrogenase domain, IPR029510=Aldehyde dehydrogenase, glutamic acid active site" CG4685 16-Dec-15 2015_12 ENSDARG00000003698(LOC100330723) YBR006W(UGA2) WBGene00000113(alh-7) ENSXETG00000021961(ALDH5A1) ENSMUSG00000035936(Aldh5a1) ENSG00000112294(ALDH5A1) "viable,visible" "chaeta,supernumerary" DRSC15621 K 0.063487575 0.113194854 0.067524299 0.612225239 0.02546745 2.944768066 FBgn0017544 SAR Scaffold Attachment Region http://flybase.net/reports/FBgn0017544.html region "dSAR, MAR, MAR/SAR" 16-Dec-15 2015_12 FBgn0036505 CG7945 http://flybase.net/reports/FBgn0036505.html FBgn0036506 protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding CG17014 CG7945 16-Dec-15 2015_12 ENSDARG00000035005(bag2) WBGene00006760(unc-23) ENSXETG00000022850(bag2) ENSMUSG00000042215(Bag2) ENSG00000112208(BAG2) viable FBgn0000902 fs(1)M111 female sterile (1) M111 http://flybase.net/reports/FBgn0000902.html gene 16-Dec-15 2015_12 female sterile FBgn0044339 17.6\gag gag http://flybase.net/reports/FBgn0044339.html transposable_element_gene gag 16-Dec-15 2015_12 FBgn0027518 CG7609 http://flybase.net/reports/FBgn0027518.html protein_coding_gene 0005053=peroxisome matrix targeting signal-2 binding 0007031=peroxisome organization 0035859=Seh1-associated complex "FBtr0085543, SEA2, BcDNA:LD21720" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site" CG7609 16-Dec-15 2015_12 ENSDARG00000025507(wdr24) YOL138C(RTC1) ENSMUSG00000025737(Wdr24) ENSG00000127580(WDR24) "viable,male fertile,female fertile,fertile" FBgn0038485 CG5255 http://flybase.net/reports/FBgn0038485.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP141 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG5255 16-Dec-15 2015_12 viable FBgn0082941 snoRNA:Me28S-A992 snoRNA:Me28S-A992 http://flybase.net/reports/FBgn0082941.html snoRNA_gene "Me28S-A992, CR34538, Me28S-Am992" CR34538 16-Dec-15 2015_12 FBgn0259576 B0617 http://flybase.net/reports/FBgn0259576.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment,unguis,arista" FBgn0046876 Obp83ef Odorant-binding protein 83ef http://flybase.net/reports/FBgn0046876.html "FBgn0037401, FBgn0051557" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "OBP83e, Odorant-binding protein 83f, Obp83e, CG31557, Pseudogene 83e, Obp83f, 83f-1, CG15583, DmelObp83ef, 83f, 83f-2" IPR006170=Pheromone/general odorant binding protein CG31557 16-Dec-15 2015_12 "viable,fertile" FBgn0052357 tRNA:CR32357 transfer RNA:CR32357 http://flybase.net/reports/FBgn0052357.html "FBgn0011917, FBgn0003808, FBgn0011918, FBgn0060142" tRNA_gene 0033436=AUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:M2:72Fb, chr3L.trna30-MetCAT, CR32357, AE002602.trna25-MetCAT, tRNA[[2]][Met], transfer RNA:met2:72Fb, transfer RNA:met2:72Fa, tRNA:M2:72Fa, tRNA:met2:72Fb, tRNA:M:CAT:AE002602-d, tRNA:met2:72Fa" CR32357 16-Dec-15 2015_12 FBgn0266105 mei-826 meiotic 826 http://flybase.net/reports/FBgn0266105.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female" FBgn0022336 dc dosach http://flybase.net/reports/FBgn0022336.html gene dos 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" spindle | maternal effect FBgn0259625 B0211 http://flybase.net/reports/FBgn0259625.html gene 16-Dec-15 2015_12 visible wing FBgn0030707 CG8916 http://flybase.net/reports/FBgn0030707.html protein_coding_gene "0004890=GABA-A receptor activity, 0005230=extracellular ligand-gated ion channel activity" 0006811=ion transport 0016021=integral component of membrane "IPR001390=Gamma-aminobutyric-acid A receptor, alpha subunit, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006201=Neurotransmitter-gated ion-channel, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG8916 16-Dec-15 2015_12 viable FBgn0259408 C272 http://flybase.net/reports/FBgn0259408.html gene 16-Dec-15 2015_12 visible "wing,chaeta,ectopic" FBgn0260762 CG42560 http://flybase.net/reports/FBgn0260762.html "FBan0030182, FBgn0050182" protein_coding_gene CG30182 CG42560 16-Dec-15 2015_12 FBgn0052061 CG32061 http://flybase.net/reports/FBgn0052061.html FBgn0036084 protein_coding_gene CG8040 CG32061 16-Dec-15 2015_12 FBgn0022148 l(2)k06006 lethal (2) k06006 http://flybase.net/reports/FBgn0022148.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085590 CG41272 http://flybase.net/reports/FBgn0085590.html FBan0041272 protein_coding_gene 16-Dec-15 2015_12 FBgn0005759 l(1)TK403 lethal (1) TK403 http://flybase.net/reports/FBgn0005759.html gene l403 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0026324 Taf10b TBP-associated factor 10b http://flybase.net/reports/FBgn0026324.html protein_coding_gene "0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0004402=histone acetyltransferase activity, 0005515=protein binding" "0006367=transcription initiation from RNA polymerase II promoter, 0043966=histone H3 acetylation" "0005634=nucleus, 0005737=cytoplasm, 0005669=transcription factor TFIID complex, 0000124=SAGA complex" "dmTAF10b, TAFII16, CG3069, TAF[[II]]16, TBP-associated factor, TBP-associated factor 16kD, TAF10b, TafII16, TAF[[II]], dtafII16, dTAF10b, Taf10, Taf16, TAF, TFIID, dTAF[[II]]16" "IPR003923=Transcription initiation factor TFIID, 23-30kDa subunit" CG3069 16-Dec-15 2015_12 ENSDARG00000068641(si:dkey-72l14.8) YDR167W(TAF10) WBGene00006392(taf-10) ENSXETG00000004906(TAF10) "ENSMUSG00000043866(Taf10),ENSMUSG00000071151" "viable,visible" trichogen cell DRSC26605 EK -0.871836093 1.259682869 -2.992211385 0.647254997 0.832574505 1.76930272 FBgn0011122 l(1)Q83 lethal (1) Q83 http://flybase.net/reports/FBgn0011122.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0034715 Oatp58Db Organic anion transporting polypeptide 58Db http://flybase.net/reports/FBgn0034715.html protein_coding_gene 0008514=organic anion transmembrane transporter activity "0006810=transport, 0015711=organic anion transport" 0016020=membrane "CG3382, 58Db, oatp 58Db" "IPR004156=Organic anion transporter polypeptide OATP, IPR020846=Major facilitator superfamily domain" CG3382 16-Dec-15 2015_12 Malpighian tubule FBgn0013478 l(1)1P2 lethal (1) 1P2 http://flybase.net/reports/FBgn0013478.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,rescuable maternal effect" "segment,germline clone" FBgn0051495 CG31495 http://flybase.net/reports/FBgn0051495.html FBgn0063630 protein_coding_gene 0005524=ATP binding CG9931 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG31495 16-Dec-15 2015_12 DRSC16762 K 0.327626616 0.509443831 -0.480955318 0.197594255 -0.729128987 1.518086278 FBgn0069938 CG41106 http://flybase.net/reports/FBgn0069938.html FBan0041106 protein_coding_gene 0035307=positive regulation of protein dephosphorylation 0071595=Nem1-Spo7 phosphatase complex IPR019168=Nuclear envelope phosphatase-regulatory subunit 1 CG41106 16-Dec-15 2015_12 FBgn0050286 CG30286 http://flybase.net/reports/FBgn0050286.html FBgn0034635 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP37, CG10450, SPH37" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG30286 16-Dec-15 2015_12 WBGene00006621(try-3) viable FBgn0052511 CR32511 http://flybase.net/reports/FBgn0052511.html pseudogene_attribute CG32511 CR32511 16-Dec-15 2015_12 "viable,fertile" FBgn0053690 CG33690 http://flybase.net/reports/FBgn0053690.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33690 16-Dec-15 2015_12 FBgn0027626 ss(2)28Aa ss(2)28Aa http://flybase.net/reports/FBgn0027626.html FBgn0027638 gene mfs(2)28Aa 16-Dec-15 2015_12 "semi-sterile,recessive" FBgn0060531 l(3)S101206a lethal (3) S101206a http://flybase.net/reports/FBgn0060531.html gene 1012/06 16-Dec-15 2015_12 lethal FBgn0034488 CG11208 http://flybase.net/reports/FBgn0034488.html FBgn0062177 protein_coding_gene "0000287=magnesium ion binding, 0030976=thiamine pyrophosphate binding, 0008949=oxalyl-CoA decarboxylase activity" 0001561=fatty acid alpha-oxidation 0005777=peroxisome anon-WO0118547.196 "IPR012001=Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain, IPR011766=Thiamine pyrophosphate enzyme, C-terminal TPP-binding, IPR029035=DHS-like NAD/FAD-binding domain, IPR012000=Thiamine pyrophosphate enzyme, central domain, IPR029061=Thiamin diphosphate-binding fold" CG11208 16-Dec-15 2015_12 ENSDARG00000020529(hacl1) YEL020C() WBGene00007143(B0334.3) ENSXETG00000008992(TEgg098b20.1) ENSMUSG00000021884(Hacl1) ENSG00000131373(HACL1) "partially lethal - majority die,some die during pupal stage" FBgn0067670 ovo::Bole\ovo ovo http://flybase.net/reports/FBgn0067670.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0262975 cnc cap-n-collar http://flybase.net/reports/FBgn0262975.html "FBgn0000338, FBgn0010824, FBgn0039062, FBgn0039063, FBgn0045881, FBgn0045892, FBgn0040590, FBgn0047182" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0046982=protein heterodimerization activity" "0007310=oocyte dorsal/ventral axis specification, 0008359=regulation of bicoid mRNA localization, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008340=determination of adult lifespan, 0008103=oocyte microtubule cytoskeleton polarization, 0042070=maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification, 0007317=regulation of pole plasm oskar mRNA localization, 0007350=blastoderm segmentation, 0045451=pole plasm oskar mRNA localization, 0060465=pharynx development, 0048813=dendrite morphogenesis, 0045450=bicoid mRNA localization, 0060322=head development, 0006979=response to oxidative stress" "0005634=nucleus, 0005703=polytene chromosome puff" "BcDNA:RE05559, Cap'n'collar, cap and collar, CNC_DROME, Cap'n'collar B, CG4566, Cap 'n' collar, anon-WO0153538.6, cap n collar, Cnc, CG4578, CNC, l(3)03921, CG13826, cap ""n"" collar, anon-WO0153538.7, cap'n'collar, cap 'n' collar, CG17894, 5134, l(3)j5E7, Nrf2, CG43286, DM12, cnc-C" "IPR008917=Transcription factor, Skn-1-like, DNA-binding domain, IPR004827=Basic-leucine zipper domain, IPR004826=Basic leucine zipper domain, Maf-type" CG43286 16-Dec-15 2015_12 ENSDARG00000042824(nfe2l2) "WBGene00004804(skn-1),WBGene00020961(sknr-1)" "ENSXETG00000021958(NFE2L1),ENSXETG00000012174(TGas039m22.1),ENSXETG00000001808(TEgg072h09.1)" " embryonic stage | stage >14 , embryonic stage | stage >=6 , embryonic stage | early " "

ubiquitous , embryonic labral segment

, embryonic mandibular segment

" FBgn0014349 ms(2)HB194 ms(2)HB194 http://flybase.net/reports/FBgn0014349.html gene 16-Dec-15 2015_12 FBgn0060330 l(3)S146006b lethal (3) S146006b http://flybase.net/reports/FBgn0060330.html gene "l(3)S146006, 1460/06" 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0017580 M(1)14E M(1)14E http://flybase.net/reports/FBgn0017580.html gene 16-Dec-15 2015_12 FBgn0013571 l(3)ry82 lethal (3) ry82 http://flybase.net/reports/FBgn0013571.html gene l(3)82 16-Dec-15 2015_12 "lethal,recessive" FBgn0039774 CDase Ceramidase http://flybase.net/reports/FBgn0039774.html FBgn0062033 protein_coding_gene 0017040=ceramidase activity "0045494=photoreceptor cell maintenance, 0016079=synaptic vesicle exocytosis, 0007268=synaptic transmission, 0035187=hatching behavior, 0046514=ceramide catabolic process, 0031629=synaptic vesicle fusion to presynaptic membrane, 0006665=sphingolipid metabolic process" "0005737=cytoplasm, 0005576=extracellular region" "cdase, CG1471, fcd, slab, anon-WO0118547.407, ceramidase, slug-a-bed" "IPR031331=Neutral/alkaline non-lysosomal ceramidase, C-terminal, IPR031329=Neutral/alkaline non-lysosomal ceramidase, N-terminal, IPR006823=Neutral/alkaline nonlysosomal ceramidase" CG1471 16-Dec-15 2015_12 ENSDARG00000012829(asah2) ENSXETG00000006612() ENSMUSG00000024887(Asah2) ENSG00000188611(ASAH2) "locomotor behavior defective,recessive,neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,increased cell death,lethal" "synaptic vesicle,synaptic vesicleslab-3),eye photoreceptor cell,rhabdomere,eye disc" FBgn0033403 CG13739 http://flybase.net/reports/FBgn0033403.html FBgn0046789 protein_coding_gene BcDNA:GH21254 CG13739 16-Dec-15 2015_12 lethal heart primordium FBgn0065381 l(2)SH1666 lethal (2) SH1666 http://flybase.net/reports/FBgn0065381.html gene l(2)SH2 1666 16-Dec-15 2015_12 "lethal,recessive" FBgn0065901 l(2)SH0200 lethal (2) SH0200 http://flybase.net/reports/FBgn0065901.html gene l(2)SH2 0200 16-Dec-15 2015_12 "lethal,recessive" FBgn0022203 l(2)k04512 lethal (2) k04512 http://flybase.net/reports/FBgn0022203.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0043845 Ama::Nrg Ama::Nrg http://flybase.net/reports/FBgn0043845.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0038771 CG4390 http://flybase.net/reports/FBgn0038771.html protein_coding_gene 0018738=S-formylglutathione hydrolase activity 0046294=formaldehyde catabolic process "IPR029058=Alpha/Beta hydrolase fold, IPR000801=Putative esterase, IPR014186=S-formylglutathione hydrolase" CG4390 16-Dec-15 2015_12 ENSDARG00000019496(esd) YJL068C() WBGene00013018(Y48G10A.1) ENSXETG00000015425(Q5M8U4_XENTR) ENSMUSG00000021996(Esd) ENSG00000139684(ESD) FBgn0053239 Ste:CG33239 Ste:CG33239 http://flybase.net/reports/FBgn0053239.html FBgn0052605 protein_coding_gene 0019887=protein kinase regulator activity 0045859=regulation of protein kinase activity 0005956=protein kinase CK2 complex "CG32605, CG33239" "IPR000704=Casein kinase II, regulatory subunit, IPR016150=Casein kinase II, regulatory subunit, beta-sheet, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG33239 16-Dec-15 2015_12 FBgn0038146 CG9799 http://flybase.net/reports/FBgn0038146.html protein_coding_gene "0006364=rRNA processing, 0009267=cellular response to starvation" 0032040=small-subunit processome "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR007319=Small-subunit processome, Utp21, IPR001680=WD40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG9799 16-Dec-15 2015_12 ENSDARG00000004774(wdr36) YLR409C(UTP21) WBGene00012887(Y45F10D.7) ENSXETG00000011004(WDR36) ENSMUSG00000038299(Wdr36) ENSG00000134987(WDR36) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC16567 E 1.477590584 0.453170864 1.884111752 0.185797449 0.800098502 0.442015867 FBgn0005211 l(3)hd lethal (3) head defect http://flybase.net/reports/FBgn0005211.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" head FBgn0024588 l(2)k02615 lethal (2) k02615 http://flybase.net/reports/FBgn0024588.html gene 26/15 16-Dec-15 2015_12 "lethal,recessive" FBgn0037659 Kdm2 Lysine (K)-specific demethylase 2 http://flybase.net/reports/FBgn0037659.html protein_coding_gene "0034647=histone demethylase activity (H3-trimethyl-K4 specific), 0008270=zinc ion binding, 0003677=DNA binding, 0004842=ubiquitin-protein transferase activity" "0007379=segment specification, 0070544=histone H3-K36 demethylation, 0033522=histone H2A ubiquitination, 0034721=histone H3-K4 demethylation, trimethyl-H3-K4-specific, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0007526=larval somatic muscle development" "0005634=nucleus, 0019005=SCF ubiquitin ligase complex, 0031519=PcG protein complex" "KDM2, FBXL19, dRING-associated factor 1, dKDM2, dkdm2, dRAF1, JmjC domain-containing histone demethylase 1, dKdm2, JHDM1, CG11033" "IPR002857=Zinc finger, CXXC-type, IPR006553=Leucine-rich repeat, cysteine-containing subtype, IPR003347=JmjC domain, IPR001810=F-box domain" CG11033 16-Dec-15 2015_12 ENSDARG00000059653(zgc:158441) ENSXETG00000015793(fbxl11) "ENSMUSG00000029475(Kdm2b),ENSMUSG00000054611(Kdm2a)" "ENSG00000089094(KDM2B),ENSG00000173120(KDM2A)" "lethal,viable,partially lethal - majority die,recessive" nucleolus FBgn0028963 Or49b Odorant receptor 49b http://flybase.net/reports/FBgn0028963.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "DOR105, AN13, 49D.1, 49b, CG17584" "IPR004117=Olfactory receptor, Drosophila" CG17584 16-Dec-15 2015_12 viable FBgn0262335 mir-2492 mir-2492 stem loop http://flybase.net/reports/FBgn0262335.html miRNA_gene "CR43042, dme-mir-2492" CR43042 16-Dec-15 2015_12 viable FBgn0085474 CG34445 http://flybase.net/reports/FBgn0085474.html "FBgn0050219, FBan0030219, FBgn0034754" protein_coding_gene "CG30219, CG13513" IPR006629=LPS-induced tumour necrosis factor alpha factor CG34445 16-Dec-15 2015_12 "viable,fertile" FBgn0039664 CG2006 http://flybase.net/reports/FBgn0039664.html protein_coding_gene IPR005636=DTW CG2006 16-Dec-15 2015_12 ENSDARG00000059386(dtwd1) WBGene00175030(Y53C12A.10) ENSXETG00000008787(TEgg073n17.1) ENSMUSG00000023330(Dtwd1) "ENSG00000104047(DTWD1),ENSG00000214280" FBgn0027971 l(3)S142909 lethal (3) S142909 http://flybase.net/reports/FBgn0027971.html gene 1429/09 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035377 CG14952 http://flybase.net/reports/FBgn0035377.html protein_coding_gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC08412 IEK -1.85987366 -3.989084073 -3.913683202 -5.010327823 1.619893523 3.329087426 FBgn0014380 RhoL Rho-like http://flybase.net/reports/FBgn0014380.html "FBgn0019864, FBgn0020619" protein_coding_gene "0003924=GTPase activity, 0005509=calcium ion binding, 0005525=GTP binding" "0007298=border follicle cell migration, 0035011=melanotic encapsulation of foreign target, 0007155=cell adhesion, 0022409=positive regulation of cell-cell adhesion, 0008360=regulation of cell shape, 0007498=mesoderm development, 0030707=ovarian follicle cell development, 0035099=hemocyte migration, 0006974=cellular response to DNA damage stimulus, 0007264=small GTPase mediated signal transduction" 0005622=intracellular "DRhoL, Rhol, D-RhoL, rhol, Rho-like, 9366, Drac3, rho-like, CG9366, Rho-Like, DmRHO-L, RhoL/Rac3, rol, rhoL, RhoG, anon-EST:CL1c2, Rac3, Mes1, G" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain" CG9366 16-Dec-15 2015_12 " embryonic stage | stage >5 , embryonic stage | stage 11 , embryonic stage -- adult stage , embryonic stage | late , embryonic stage | stage 5 , embryonic stage | stage >11 , embryonic stage , embryonic stage | stage 6-10 , embryonic stage | cellular blastoderm " " mesoderm

, head mesoderm

, hemocyte

, mesoderm anlage

,

ubiquitous , ventral furrow

, ventral furrow | anterior

" "immune response defective,neuroanatomy defective,viable,lethal" "intersegmental nerve,anterior fascicle & synapse | supernumerary,nurse cell,follicle cell,border follicle cell,polar follicle cell,hemocyte" DRSC16824 IE -0.271317847 -2.091840094 0.509538778 1.628428859 0.146224726 0.784276087 FBgn0034439 CG10062 http://flybase.net/reports/FBgn0034439.html FBgn0044645 protein_coding_gene anon-WO0140519.226 IPR007484=Peptidase M28 CG10062 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) "viable,visible" trichogen cell FBgn0029736 CG4041 http://flybase.net/reports/FBgn0029736.html protein_coding_gene "0005524=ATP binding, 0005096=GTPase activator activity, 0004672=protein kinase activity" "0006468=protein phosphorylation, 0043087=regulation of GTPase activity, 0007030=Golgi organization" "IPR000195=Rab-GTPase-TBC domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR001763=Rhodanese-like domain" CG4041 16-Dec-15 2015_12 ENSDARG00000013667(tbck) WBGene00016352(tbck-1) ENSXETG00000027870(TBCK) ENSMUSG00000028030(Tbck) ENSG00000145348(TBCK) viable FBgn0038745 CG4538 http://flybase.net/reports/FBgn0038745.html protein_coding_gene "0051082=unfolded protein binding, 0004252=serine-type endopeptidase activity, 0005524=ATP binding" "0006508=proteolysis, 0006457=protein folding" "0009368=endopeptidase Clp complex, 0005739=mitochondrion" ClpX "IPR003593=AAA+ ATPase domain, IPR019489=Clp ATPase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR004487=Clp protease, ATP-binding subunit ClpX" CG4538 16-Dec-15 2015_12 ENSDARG00000067796(LOC100332309) YBR227C(MCX1) WBGene00008412(D2030.2) ENSXETG00000006656(clpx) ENSMUSG00000015357(Clpx) ENSG00000166855(CLPX) "viable,visible" "trichogen cell,supernumerary" FBgn0033580 CG13231 http://flybase.net/reports/FBgn0033580.html protein_coding_gene CG13231 16-Dec-15 2015_12 viable DRSC26554 K -0.282507257 0.420596799 0.103653311 -0.233349374 0.779226089 -2.05662281 FBgn0016850 l(1)N31 lethal (1) N31 http://flybase.net/reports/FBgn0016850.html gene N31 16-Dec-15 2015_12 "lethal,recessive" FBgn0038070 CG6753 http://flybase.net/reports/FBgn0038070.html protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process "IPR006693=Partial AB-hydrolase lipase domain, IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold" CG6753 16-Dec-15 2015_12 YKL140W(TGL1) ENSXETG00000009273(lipA) viable FBgn0037547 CG7910 http://flybase.net/reports/FBgn0037547.html protein_coding_gene "0016884=carbon-nitrogen ligase activity, with glutamine as amido-N-donor, 0017064=fatty acid amide hydrolase activity" 0051726=regulation of cell cycle "IPR023631=Amidase signature domain, IPR000120=Amidase" CG7910 16-Dec-15 2015_12 YDR242W(AMD2) ENSMUSG00000034171(Faah) FBgn0067347 l(3)95Ee lethal (3) 95Ee http://flybase.net/reports/FBgn0067347.html gene 16-Dec-15 2015_12 "lethal,recessive" "eye,somatic clone,wing vein,wing margin,macrochaeta,embryo" FBgn0014085 anon-20ABb anon-20ABb http://flybase.net/reports/FBgn0014085.html gene 16-Dec-15 2015_12 FBgn0065269 l(2)SH2060 lethal (2) SH2060 http://flybase.net/reports/FBgn0065269.html gene l(2)SH2 2060 16-Dec-15 2015_12 "lethal,recessive" FBgn0035311 CR15821 http://flybase.net/reports/FBgn0035311.html pseudogene_attribute CG15821 CR15821 16-Dec-15 2015_12 FBgn0061511 fs(2)AL289 fs(2)AL289 http://flybase.net/reports/FBgn0061511.html gene AL289 16-Dec-15 2015_12 "female sterile,heat sensitive" FBgn0040655 CG15659 http://flybase.net/reports/FBgn0040655.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034880 ItgaPS5 Integrin alphaPS5 subunit http://flybase.net/reports/FBgn0034880.html protein_coding_gene "0046982=protein heterodimerization activity, 0004872=receptor activity, 0050839=cell adhesion molecule binding" "0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0001555=oocyte growth, 0007155=cell adhesion, 0033627=cell adhesion mediated by integrin, 0007160=cell-matrix adhesion" "0008305=integrin complex, 0016021=integral component of membrane" "alphaPS5 integrin, ItgalphaPS5, CG5372, alpha-PS5, integrin alphaPS5 subunit, CT17068, alphaPS5, Integrin alphaPS5 subunit" "IPR000413=Integrin alpha chain, IPR013519=Integrin alpha beta-propellor, IPR013649=Integrin alpha-2" CG5372 16-Dec-15 2015_12 viable DRSC04501 K -0.429958661 -0.457652414 -0.058476411 -0.415311309 3.064318978 1.05594683 FBgn0027656 h::hkb h::hkb http://flybase.net/reports/FBgn0027656.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal,female" FBgn0001564 l(1)19Fe lethal (1) 19Fe http://flybase.net/reports/FBgn0001564.html gene "W4, l(1)W-4, 16, W-4, section 16, w-4" 16-Dec-15 2015_12 "lethal,recessive" FBgn0033212 LRR Leucine-rich repeat http://flybase.net/reports/FBgn0033212.html FBgn0033211 protein_coding_gene 0017024=myosin I binding "0050777=negative regulation of immune response, 0042384=cilium assembly, 0017085=response to insecticide, 1901223=negative regulation of NIK/NF-kappaB signaling, 0006955=immune response" 0005927=muscle tendon junction "leucine-rich repeat, Dcarmil, CG1399, Dmel\LRR, CG1576" "IPR003590=Leucine-rich repeat, ribonuclease inhibitor subtype, IPR001611=Leucine-rich repeat" CG1399 16-Dec-15 2015_12 ENSDARG00000063700 WBGene00010641(crml-1) "ENSMUSG00000021338(Lrrc16a),ENSMUSG00000022211(Lrrc16b)" "ENSG00000079691(LRRC16A),ENSG00000186648(LRRC16B)" viable FBgn0000644 Fcp3C Follicle cell protein 3C http://flybase.net/reports/FBgn0000644.html FBgn0041573 protein_coding_gene "CG4015, EG:140G11.2, Ecp3C, VMP3C" CG4015 16-Dec-15 2015_12 " oogenesis stage | stage S9-11 , adult stage && oogenesis stage " follicle cell

"viable,fertile" FBgn0017556 Prosë±4T2 "Proteasome ë±4 subunit, Testis-specific 2" http://flybase.net/reports/FBgn0017556.html protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0019773=proteasome core complex, alpha-subunit complex" "alpha4t2_dm, alpha4t2, unnamed, Pros28.1B, dalpha7, pros28.1B, alpha4T2, 20S proteasome, Prosalpha4T2, Proteasome 28kD subunit 1B, a4-t2, testes-specific proteasome subunit, 20s proteasome, CG4569" "IPR023332=Proteasome A-type subunit, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR001353=Proteasome, subunit alpha/beta" CG4569 16-Dec-15 2015_12 YOL038W(PRE6) WBGene00003925(pas-4) "partially lethal - majority die,some die during pupal stage" FBgn0266534 CG45095 http://flybase.net/reports/FBgn0266534.html protein_coding_gene CG45095 16-Dec-15 2015_12 FBgn0032462 CG16800 http://flybase.net/reports/FBgn0032462.html protein_coding_gene CG16800 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0266620 CR45127 http://flybase.net/reports/FBgn0266620.html non_protein_coding_gene CR45127 16-Dec-15 2015_12 FBgn0065166 l(3)SH033 lethal (3) SH033 http://flybase.net/reports/FBgn0065166.html gene l(2)SH3 033 16-Dec-15 2015_12 "lethal,recessive" FBgn0010679 l(2)s1864 lethal (2) s1864 http://flybase.net/reports/FBgn0010679.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033363 CG13744 http://flybase.net/reports/FBgn0033363.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP67, c-SP67" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG13744 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0051647 CR31647 http://flybase.net/reports/FBgn0051647.html FBgn0063057 non_protein_coding_gene "CG31647, BcDNA:RE16275" CR31647 16-Dec-15 2015_12 FBgn0016970 l(2)k10201 lethal (2) k10201 http://flybase.net/reports/FBgn0016970.html "FBgn0033409, FBgn0033410" protein_coding_gene 0046872=metal ion binding 0007275=multicellular organismal development "CG8803, B, CG13951" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG13951 16-Dec-15 2015_12 "lethal,recessive,wild-type,viable" FBgn0028892 CG4161 http://flybase.net/reports/FBgn0028892.html protein_coding_gene 0051998=protein carboxyl O-methyltransferase activity 0006479=protein methylation BG:DS03023.2 IPR002791=Domain of unknown function DUF89 CG4161 16-Dec-15 2015_12 ENSDARG00000055676(zgc:110816) YMR027W() WBGene00009290(F31D4.2) ENSXETG00000008483(BC075279.1) ENSMUSG00000061759(1700052N19Rik) ENSG00000146476(C6orf211) "partially lethal - majority die,some die during pupal stage" FBgn0260384 GSd464 http://flybase.net/reports/FBgn0260384.html gene 16-Dec-15 2015_12 lethal FBgn0014357 ms(2)HB441 ms(2)HB441 http://flybase.net/reports/FBgn0014357.html gene 16-Dec-15 2015_12 FBgn0032181 CG13133 http://flybase.net/reports/FBgn0032181.html protein_coding_gene "IPR031107=Small heat shock protein HSP20, IPR002068=Alpha crystallin/Hsp20 domain, IPR008978=HSP20-like chaperone" CG13133 16-Dec-15 2015_12 FBgn0010800 l(3)03471 lethal (3) 03471 http://flybase.net/reports/FBgn0010800.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014207 l(1)17Ab lethal (1) 17Ab http://flybase.net/reports/FBgn0014207.html gene 17516 16-Dec-15 2015_12 lethal FBgn0060377 l(3)S135409 lethal (3) S135409 http://flybase.net/reports/FBgn0060377.html gene 1354/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0001576 l(1)3063 lethal (1) 3063 http://flybase.net/reports/FBgn0001576.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030494 Cpr12A Cuticular protein 12A http://flybase.net/reports/FBgn0030494.html FBgn0063080 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG15757, BcDNA:LP12385" IPR000618=Insect cuticle protein CG15757 16-Dec-15 2015_12 viable FBgn0264005 Hmx H6-like-homeobox http://flybase.net/reports/FBgn0264005.html "FBgn0038522, FBgn0085448, FBgn0038521, FBgn0014858, FBgn0038520" protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "CG34419, CG5829, DHmx, CG18139, CG5832, CG43748" "IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG43748 16-Dec-15 2015_12 "WBGene00004024(php-3),WBGene00003779(nob-1)" "ENSMUSG00000035187(Nkx6-1),ENSMUSG00000041309(Nkx6-2),ENSMUSG00000063672(Nkx6-3)" ENSG00000188620(HMX3) FBgn0053282 CG33282 http://flybase.net/reports/FBgn0053282.html FBgn0031521 protein_coding_gene 0015145=monosaccharide transmembrane transporter activity "0015749=monosaccharide transport, 0055085=transmembrane transport" "0016021=integral component of membrane, 0016020=membrane" CG15407 "IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site" CG33282 16-Dec-15 2015_12 viable FBgn0082989 snoRNA:ë¬28S-2442a snoRNA:ë¬28S-2442a http://flybase.net/reports/FBgn0082989.html snoRNA_gene "Psi 28S-2442a, CR34613, psi28s-2442a" CR34613 16-Dec-15 2015_12 FBgn0032549 CG4650 http://flybase.net/reports/FBgn0032549.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH197 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG4650 16-Dec-15 2015_12 viable FBgn0011851 tRNA:E4:62Aa transfer RNA:glu4:62Aa http://flybase.net/reports/FBgn0011851.html "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052327, FBgn0060250" tRNA_gene "0033460=GAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3L.trna6-GluCTC, AE002584.trna6-GluCTC, tRNA:E:CTC:AE002584-d, tRNA:Glu, CR32327, tRNA:E4, tRNA:glu4:62Aa" CR32327 16-Dec-15 2015_12 FBgn0262776 Su(E1)-J http://flybase.net/reports/FBgn0262776.html gene 16-Dec-15 2015_12 FBgn0053741 snmRNA:430:CR33741 snmRNA:430:CR33741 http://flybase.net/reports/FBgn0053741.html non_protein_coding_gene CR33741 CR33741 16-Dec-15 2015_12 FBgn0037769 CG12419 http://flybase.net/reports/FBgn0037769.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0011097 l(1)Q57 lethal (1) Q57 http://flybase.net/reports/FBgn0011097.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0000194 bla bladderwing http://flybase.net/reports/FBgn0000194.html gene 16-Dec-15 2015_12 "visible,partially lethal - majority die,female,female sterile,lethal,maternal effect,recessive,male sterile,viable,male,reduced,male fertile" "wing,eye" FBgn0016827 l(1)MZ14 lethal (1) MZ14 http://flybase.net/reports/FBgn0016827.html gene M14 16-Dec-15 2015_12 "lethal,recessive" FBgn0266349 CR44998 http://flybase.net/reports/FBgn0266349.html non_protein_coding_gene CR44998 16-Dec-15 2015_12 FBgn0060416 l(3)S129515 lethal (3) S129515 http://flybase.net/reports/FBgn0060416.html gene 1295/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0266231 CR44926 http://flybase.net/reports/FBgn0266231.html non_protein_coding_gene lincRNA.685 CR44926 16-Dec-15 2015_12 FBgn0019764 l(1)5g11 lethal (1) 5g11 http://flybase.net/reports/FBgn0019764.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0045854 en(lz)Y en(lz)Y http://flybase.net/reports/FBgn0045854.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0036024 CG18180 http://flybase.net/reports/FBgn0036024.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP151 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG18180 16-Dec-15 2015_12 viable FBgn0032724 CG10428 http://flybase.net/reports/FBgn0032724.html protein_coding_gene "IPR025714=Methyltransferase domain, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR010987=Glutathione S-transferase, C-terminal-like" CG10428 16-Dec-15 2015_12 ENSDARG00000036494(gstcd) ENSXETG00000014108(GSTCD) ENSMUSG00000028018(Gstcd) ENSG00000138780(GSTCD) FBgn0016960 tkv::tor tkv::tor http://flybase.net/reports/FBgn0016960.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0065463 l(2)SH1357 lethal (2) SH1357 http://flybase.net/reports/FBgn0065463.html gene l(2)SH2 1357 16-Dec-15 2015_12 "lethal,recessive" FBgn0004982 Bld Blond http://flybase.net/reports/FBgn0004982.html gene 16-Dec-15 2015_12 "viable,fertile,visible,dominant" "macrochaeta,microchaeta" FBgn0004633 CAT-repeat CAT repeat http://flybase.net/reports/FBgn0004633.html repeat_region 16-Dec-15 2015_12 FBgn0026305 anon-16Fd anon-16Fd http://flybase.net/reports/FBgn0026305.html gene HL-III 16-Dec-15 2015_12 FBgn0052636 CR32636 http://flybase.net/reports/FBgn0052636.html FBgn0040863 non_protein_coding_gene "CG15746, CG32636" CR32636 16-Dec-15 2015_12 FBgn0031701 TotM Turandot M http://flybase.net/reports/FBgn0031701.html protein_coding_gene "0050830=defense response to Gram-positive bacterium, 0009617=response to bacterium, 0034605=cellular response to heat" "0005576=extracellular region, 0005615=extracellular space" "Turandot M, Turandot, CG14027, Tot M, totM, TOTM, tot" IPR010825=Stress-inducible humoral factor Turandot CG14027 16-Dec-15 2015_12 viable FBgn0029877 CG17717 http://flybase.net/reports/FBgn0029877.html FBgn0061447 protein_coding_gene 0008270=zinc ion binding BcDNA:AT19932 "IPR011016=Zinc finger, RING-CH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG17717 16-Dec-15 2015_12 "ENSG00000099785(MARCH2),ENSG00000173926(MARCH3)" FBgn0264727 CR43995 http://flybase.net/reports/FBgn0264727.html non_protein_coding_gene CR43995 16-Dec-15 2015_12 FBgn0029066 l(1)G0280 lethal (1) G0280 http://flybase.net/reports/FBgn0029066.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025728 tra2::U2af50 tra2::U2af50 http://flybase.net/reports/FBgn0025728.html engineered_fusion_gene TRA-2/dU2AF[50] 16-Dec-15 2015_12 FBgn0030056 CG11284 http://flybase.net/reports/FBgn0030056.html protein_coding_gene 0004089=carbonate dehydratase activity CG11285 "IPR018433=Carbonic anhydrase, putative, insect, IPR001148=Alpha carbonic anhydrase, IPR023561=Carbonic anhydrase, alpha-class" CG11284 16-Dec-15 2015_12 viable FBgn0266734 CR45207 http://flybase.net/reports/FBgn0266734.html non_protein_coding_gene CR45207 16-Dec-15 2015_12 FBgn0262164 Z0189 http://flybase.net/reports/FBgn0262164.html gene gene ; SO:0000704 16-Dec-15 2015_12 viable photoreceptor cell R7 FBgn0002209 l(3)67BDg lethal (3) 67BDg http://flybase.net/reports/FBgn0002209.html gene 16-Dec-15 2015_12 lethal FBgn0020300 geko geko http://flybase.net/reports/FBgn0020300.html "FBgn0036779, FBgn0040790, FBgn0047124" protein_coding_gene "0045471=response to ethanol, 0007608=sensory perception of smell, 0048149=behavioral response to ethanol" "gk, CG13696, geko, CT33153, Geko, CG13695, BcDNA:RE30284" CG13695 16-Dec-15 2015_12 smell perception defective FBgn0050209 tRNA:CR30209 transfer RNA:CR30209 http://flybase.net/reports/FBgn0050209.html FBgn0060015 tRNA_gene 0033416=UGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002575.trna12-TrpCCA, chr2R.trna56-TrpCCA, CR30209, tRNA:W:CCA:AE002575-c" CR30209 16-Dec-15 2015_12 FBgn0003728 tnt tent http://flybase.net/reports/FBgn0003728.html gene 16-Dec-15 2015_12 "male sterile,visible" "macrochaeta,wing" FBgn0023453 ches chestnut http://flybase.net/reports/FBgn0023453.html gene 16-Dec-15 2015_12 visible pigment cell FBgn0004735 l(3)85Db lethal (3) 85Db http://flybase.net/reports/FBgn0004735.html gene 16-Dec-15 2015_12 lethal FBgn0051263 CG31263 http://flybase.net/reports/FBgn0051263.html protein_coding_gene 16-Dec-15 2015_12 FBgn0031161 CG15445 http://flybase.net/reports/FBgn0031161.html protein_coding_gene 0022008=neurogenesis NUB1 "IPR015940=Ubiquitin-associated domain, IPR029071=Ubiquitin-related domain, IPR009060=UBA-like" CG15445 16-Dec-15 2015_12 ENSDARG00000061417(LOC100330264) ENSMUSG00000028954(Nub1) ENSG00000013374(NUB1) "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0020564 anon-II-E9 anon-II-E9 http://flybase.net/reports/FBgn0020564.html gene 16-Dec-15 2015_12 Bolwig nerve FBgn0053177 CG33177 http://flybase.net/reports/FBgn0053177.html FBgn0030609 protein_coding_gene 0004364=glutathione transferase activity CG5579 "IPR001129=Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein, IPR023352=Membrane associated eicosanoid/glutathione metabolism-like domain" CG33177 16-Dec-15 2015_12 "ENSDARG00000032618(mgst1),ENSDARG00000022165(zgc:92357)" ENSXETG00000014173(PTGES) ENSMUSG00000008540(Mgst1) ENSG00000008394(MGST1) FBgn0061486 road regulator of armadillo http://flybase.net/reports/FBgn0061486.html gene 0016055=Wnt signaling pathway 0005634=nucleus 16-Dec-15 2015_12 FBgn0003647 Su(z)6 Suppressor of zeste 6 http://flybase.net/reports/FBgn0003647.html gene 16-Dec-15 2015_12 male sterile pigment cell FBgn0039043 CG17121 http://flybase.net/reports/FBgn0039043.html protein_coding_gene "0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site" CG17121 16-Dec-15 2015_12 "YDL114W(),YLR426W()" "partially lethal - majority die,some die during pupal stage" FBgn0051097 CG31097 http://flybase.net/reports/FBgn0051097.html FBgn0039318 protein_coding_gene 0022008=neurogenesis CG13665 "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG31097 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0065774 l(2)SH0456 lethal (2) SH0456 http://flybase.net/reports/FBgn0065774.html gene l(2)SH2 0456 16-Dec-15 2015_12 "lethal,recessive" FBgn0030421 CG3812 http://flybase.net/reports/FBgn0030421.html protein_coding_gene 0003841=1-acylglycerol-3-phosphate O-acyltransferase activity 0008654=phospholipid biosynthetic process "0016020=membrane, 0000502=proteasome complex" "AGPAT1, AGPAT2" "IPR002123=Phospholipid/glycerol acyltransferase, IPR004552=1-acyl-sn-glycerol-3-phosphate acyltransferase" CG3812 16-Dec-15 2015_12 ENSDARG00000068437(agpat2) YDL052C(SLC1) WBGene00011543(acl-2) ENSXETG00000005222(AGPAT1) "ENSMUSG00000034254(Agpat1),ENSMUSG00000026922(Agpat2)" "ENSG00000206255,ENSG00000206324,ENSG00000204310(AGPAT1),ENSG00000169692(AGPAT2)" "viable,fertile" FBgn0061068 l(3)S018812b lethal (3) S018812b http://flybase.net/reports/FBgn0061068.html gene 0188/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0022353 anon-25Da anon-25Da http://flybase.net/reports/FBgn0022353.html gene e1 16-Dec-15 2015_12 FBgn0014044 Su(tor)2-180 Su(tor)2-180 http://flybase.net/reports/FBgn0014044.html gene 16-Dec-15 2015_12 "female sterile,semidominant" FBgn0262808 CG43179 http://flybase.net/reports/FBgn0262808.html protein_coding_gene chr3R_10081851_10082659.0 CG43179 16-Dec-15 2015_12 FBgn0010541 l(2)03497 lethal (2) 03497 http://flybase.net/reports/FBgn0010541.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0261454 scaRNA:MeU4-A65 small Cajal body-specific RNA : MeU4-A65 http://flybase.net/reports/FBgn0261454.html snoRNA_gene 0030563=snRNA 2'-O-ribose methylation guide activity 0015030=Cajal body "scaRNA:mgU4-65, scaRNA:CG7510-a, mgU4-65" CR43571 16-Dec-15 2015_12 FBgn0034802 CG3800 http://flybase.net/reports/FBgn0034802.html "FBgn0025228, FBgn0025268, FBgn0034801, FBgn0045797" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "CG11716, anon-fast-evolving-2B6, anon-EST:fe2B6, unnamed, BEST:GM06241, anon-EST:fe1B4, anon-fast-evolving-1B4" "IPR001878=Zinc finger, CCHC-type" CG3800 16-Dec-15 2015_12 "ENSDARG00000070922(wu:fj34c03),ENSDARG00000045776(zff9),ENSDARG00000059405" YNL255C(GIS2) WBGene00019537(K08D12.3) ENSXETG00000025147(znf9) "ENSMUSG00000030057(Cnbp),ENSMUSG00000031330(Zcchc13)" "ENSG00000169714(CNBP),ENSG00000187969(ZCCHC13)" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0085514 CG40754 http://flybase.net/reports/FBgn0085514.html FBan0040754 protein_coding_gene 16-Dec-15 2015_12 FBgn0020443 Elf Ef1ë±-like factor http://flybase.net/reports/FBgn0020443.html protein_coding_gene "0003924=GTPase activity, 0003747=translation release factor activity, 0005525=GTP binding, 0008079=translation termination factor activity" 0006415=translational termination 0005829=cytosol "DSUP35, CG6382, eRF3, delf, Dsup35, dsup35, eukaryotic release factor 3, elf" "IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR031157=Tr-type G domain, conserved site, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR009818=Ataxin-2, C-terminal, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR004160=Translation elongation factor EFTu/EF1A, C-terminal" CG6382 16-Dec-15 2015_12 "ENSDARG00000014123(gspt1l),ENSDARG00000031048(gspt1)" YDR172W(SUP35) WBGene00010405(H19N07.1) ENSXETG00000005540() "ENSMUSG00000062203(Gspt1),ENSMUSG00000071723(Gspt2)" "ENSG00000103342(GSPT1),ENSG00000189369(GSPT2)" adult stage | male " testis

, spermatid

, spermatogonium

, spermatocyte

" "viable,fertile,lethal,recessive,male sterile,cytokinesis defective,lethal - all die before end of larval stage,some die during larval stage" "onion stage spermatid,Nebenkern,aster" FBgn0063407 l(3)3450-P lethal (3) 3450-P http://flybase.net/reports/FBgn0063407.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020529 l(3)CB24 lethal (3) CB24 http://flybase.net/reports/FBgn0020529.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031832 CG9596 http://flybase.net/reports/FBgn0031832.html protein_coding_gene "0046331=lateral inhibition, 0030488=tRNA methylation" 0031515=tRNA (m1A) methyltransferase complex IPR017423=tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 CG9596 16-Dec-15 2015_12 ENSDARG00000042344(trmt6) YNL062C(GCD10) WBGene00014120(ZK858.7) ENSXETG00000004501(BC076885.1) ENSMUSG00000037376(Trmt6) ENSG00000089195(TRMT6) "viable,fertile,visible" "chaeta,trichogen cell" FBgn0025355 SuUR Suppressor of Under-Replication http://flybase.net/reports/FBgn0025355.html FBgn0036120 protein_coding_gene 0003682=chromatin binding "0006260=DNA replication, 0008156=negative regulation of DNA replication, 0051276=chromosome organization, 0032877=positive regulation of DNA endoreduplication, 0042023=DNA endoreduplication, 0031507=heterochromatin assembly, 0006333=chromatin assembly or disassembly" "0000775=chromosome, centromeric region, 0005721=pericentric heterochromatin, 0000792=heterochromatin, 0005725=intercalary heterochromatin, 0005700=polytene chromosome, 0005724=nuclear telomeric heterochromatin, 0005634=nucleus" "Dromel_CG7869_FBtr0076203_suur_mORF, CG7869, Su(UR)ES, Suppressor of underreplication, SU(UR), Suppressor of Under- replication, Su(UR), Suppressor of UnderReplication, Suppressor of Underreplication protein, SUUR, suppressor of under-replication, Suppressor of Underreplication, su(UR)ES, suppressor of underreplication" IPR027417=P-loop containing nucleoside triphosphate hydrolase CG7869 16-Dec-15 2015_12 "viable,fertile,suppressor of variegation,dominant,enhancer of variegation,wild-type,female sterile,partially,female fertile,size defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "polytene chromosomeSgs3.PD,polytene chromosome & salivary gland | conditional - heat sensitiveSgs3.PD,intercalary heterochromatinSgs3.PD,embryonic/larval salivary gland,polytene chromosome weak point,intercalary heterochromatin,polytene chromosome band,polytene chromosome,heterochromatin,beta-heterochromatin,alpha-heterochromatin,polytene chromosome band & salivary gland | ectopic,polytene chromosomeAB1,salivary gland" FBgn0267580 CR45920 http://flybase.net/reports/FBgn0267580.html non_protein_coding_gene pri-mir-316 CR45920 16-Dec-15 2015_12 FBgn0030794 CG13005 http://flybase.net/reports/FBgn0030794.html protein_coding_gene CG13005 16-Dec-15 2015_12 viable FBgn0264435 CR43853 http://flybase.net/reports/FBgn0264435.html non_protein_coding_gene lincRNA.142 CR43853 16-Dec-15 2015_12 FBgn0004488 l(1)air15 lethal aberrant immune response 15 http://flybase.net/reports/FBgn0004488.html gene "air15, l(1)air[15]" 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0020415 Idgf2 Imaginal disc growth factor 2 http://flybase.net/reports/FBgn0020415.html FBgn0027923 protein_coding_gene "0008084=imaginal disc growth factor receptor binding, 0004568=chitinase activity" "0007444=imaginal disc development, 0005975=carbohydrate metabolic process, 0006032=chitin catabolic process" 0005576=extracellular region "BG:DS02780.4, IDGF, idgf2, IDGF-2, IDGF2, CG4475, DmIDGF2" "IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain, IPR011583=Chitinase II, IPR015520=Imaginal disc growth factor, IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain" CG4475 16-Dec-15 2015_12 " embryonic stage , larval stage | third instar , embryonic stage && larval stage , adult stage && oogenesis stage " " yolk

, lymph gland

, embryonic/larval salivary gland

, ventral furrow | vicinity of

, oocyte

, embryonic/larval fat body

, imaginal disc

, amnioproctodeal invagination | vicinity of

, embryonic/larval tracheal system

, cephalic furrow | vicinity of

, nurse cell

, ring gland

, larval brain

, larval optic lobe

" FBgn0029105 alpha-catenin-related alpha-catenin related http://flybase.net/reports/FBgn0029105.html FBgn0034941 protein_coding_gene "0003779=actin binding, 0051015=actin filament binding" "0007155=cell adhesion, 0007266=Rho protein signal transduction" 0005915=zonula adherens "CG2987, alpha-catenin-related, alpha-catenin-Related" "IPR030045=Alpha-catulin 1, IPR006077=Vinculin/alpha-catenin" CG2987 16-Dec-15 2015_12 ENSDARG00000018162(si:ch211-254e15.1) WBGene00000832(ctn-1) ENSXETG00000018934(CTNNAL1) ENSMUSG00000038816(Ctnnal1) ENSG00000119326(CTNNAL1) viable FBgn0004800 fs(2)ltoQZ47 female sterile (2) ltoQZ47 http://flybase.net/reports/FBgn0004800.html gene "0007297=ovarian follicle cell migration, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile FBgn0026653 l(2)3A2 lethal (2) 3A2 http://flybase.net/reports/FBgn0026653.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0052488 CG32488 http://flybase.net/reports/FBgn0052488.html FBgn0035386 protein_coding_gene "0004721=phosphoprotein phosphatase activity, 0004035=alkaline phosphatase activity, 0016791=phosphatase activity" 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" "Phos32488, CG2077, 20151345" "IPR023215=Nitrophenylphosphatase-like domain, IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR006349=2-phosphoglycolate phosphatase, eukaryotic, IPR023214=HAD-like domain" CG32488 16-Dec-15 2015_12 YDL236W(PHO13) "WBGene00016892(C53A3.2),WBGene00019604(K09H11.7),WBGene00018424(F44E7.2)" "ENSMUSG00000043445(Pgp),ENSMUSG00000068221(Pdxp)" FBgn0037332 Hcs Holocarboxylase synthetase http://flybase.net/reports/FBgn0037332.html FBgn0045161 protein_coding_gene "0004080=biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity, 0004077=biotin-[acetyl-CoA-carboxylase] ligase activity" "0018054=peptidyl-lysine biotinylation, 0009408=response to heat, 0071110=histone biotinylation" 0005700=polytene chromosome "HSC, HCS, CG14670, NEST:bs27h05, holocarboxylase synthetase" "IPR003142=Biotin protein ligase, C-terminal, IPR004408=Biotin--acetyl-CoA-carboxylase ligase, IPR004143=Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain" CG14670 16-Dec-15 2015_12 YDL141W(BPL1) WBGene00000259(bpl-1) ENSXETG00000013028(HLCS) ENSMUSG00000040820(Hlcs) ENSG00000159267(HLCS) "short lived,heat stress response defective,male,female,viable,fertile" FBgn0053156 CG33156 http://flybase.net/reports/FBgn0053156.html "FBgn0033854, FBgn0050063" protein_coding_gene 0003951=NAD+ kinase activity "0019674=NAD metabolic process, 0006741=NADP biosynthetic process" "0005634=nucleus, 0005737=cytoplasm" "CG6152, CG30063" "IPR002504=NAD kinase, IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR017438=Inorganic polyphosphate/ATP-NAD kinase, domain 1, IPR017437=ATP-NAD kinase, PpnK-type, all-beta" CG33156 16-Dec-15 2015_12 "ENSDARG00000006577,ENSDARG00000060362(nadk)" "YEL041W(YEF1),YJR049C(UTR1)" ENSXETG00000019605(Q6DJ74_XENTR) ENSMUSG00000029063(Nadk) ENSG00000008130(NADK) viable FBgn0021800 Reph Regulator of eph expression http://flybase.net/reports/FBgn0021800.html FBgn0031572 protein_coding_gene "0048013=ephrin receptor signaling pathway, 0007422=peripheral nervous system development" "reph, l(2)k16918, regulator of eph expression, CG3920, lethal (2) k16918" CG3920 16-Dec-15 2015_12 "neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,lethal,recessive,viable,fertile,visible" "commissure,longitudinal connective,medulla neuropil | third instar larval stage,lamina furrow,cell autonomous,somatic clone,mesothoracic tergum" FBgn0038958 CG13857 http://flybase.net/reports/FBgn0038958.html protein_coding_gene CG13857 16-Dec-15 2015_12 viable FBgn0060327 l(3)S146508 lethal (3) S146508 http://flybase.net/reports/FBgn0060327.html gene 1465/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0263975 CR43727 http://flybase.net/reports/FBgn0263975.html pseudogene_attribute CR43727 16-Dec-15 2015_12 FBgn0002975 ny notchy http://flybase.net/reports/FBgn0002975.html gene 16-Dec-15 2015_12 "visible,cold sensitive" "wing,cold sensitive" FBgn0023049 l(1)3An lethal (1) 3An http://flybase.net/reports/FBgn0023049.html gene C3/47.16 16-Dec-15 2015_12 "lethal,recessive" FBgn0027578 CG14526 http://flybase.net/reports/FBgn0027578.html FBgn0039614 protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis 0005576=extracellular region BcDNA:GH07188 "IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13, IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain" CG14526 16-Dec-15 2015_12 viable FBgn0014237 l(2)31Et lethal (2) 31Et http://flybase.net/reports/FBgn0014237.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0004983 bleg black leg http://flybase.net/reports/FBgn0004983.html gene 16-Dec-15 2015_12 "visible,recessive,body color defective" "leg,wing" FBgn0039271 CG11839 http://flybase.net/reports/FBgn0039271.html protein_coding_gene 0005515=protein binding 0005654=nucleoplasm "CT36969, Znf830" CG11839 16-Dec-15 2015_12 WBGene00011411(sel-13) ENSXETG00000010494(ccdc16) ENSMUSG00000046010(Zfp830) ENSG00000198783(ZNF830) "viable,neurophysiology defective" embryonic/larval neuromuscular junction | larval stage FBgn0038033 CG10097 http://flybase.net/reports/FBgn0038033.html "FBgn0044571, FBgn0052919, FBtr0082603, FBpp0082073, FBtr0082604, FBpp0082074, FBtr0082605, FBpp0082075" protein_coding_gene 0080019=fatty-acyl-CoA reductase (alcohol-forming) activity "anon-WO0140519.58, CT28427, CG32919" "IPR013120=Male sterility, NAD-binding, IPR026055=Fatty acyl-CoA reductase, IPR016040=NAD(P)-binding domain" CG10097 16-Dec-15 2015_12 "viable,fertile" FBgn0005326 Osw Outspreadwing http://flybase.net/reports/FBgn0005326.html gene Outspread wing 16-Dec-15 2015_12 visible wing FBgn0267890 CR46178 http://flybase.net/reports/FBgn0267890.html pseudogene_attribute CG12717-related CR46178 16-Dec-15 2015_12 FBgn0053371 5SrRNA-ë¬:CR33371 5SrRNA-ë¬:CR33371 http://flybase.net/reports/FBgn0053371.html pseudogene_attribute CR33371 CR33371 16-Dec-15 2015_12 FBgn0267687 CR46023 http://flybase.net/reports/FBgn0267687.html non_protein_coding_gene CR46023 16-Dec-15 2015_12 FBgn0065700 l(2)SH0623 lethal (2) SH0623 http://flybase.net/reports/FBgn0065700.html gene l(2)SH2 0623 16-Dec-15 2015_12 "lethal,recessive" FBgn0002855 Acp26Aa Accessory gland protein 26Aa http://flybase.net/reports/FBgn0002855.html protein_coding_gene "0005179=hormone activity, 0042802=identical protein binding" "0048042=regulation of post-mating oviposition, 0030728=ovulation, 0018991=oviposition, 0045297=post-mating behavior, 0007618=mating, 0046692=sperm competition, 0032504=multicellular organism reproduction" "0005576=extracellular region, 0005615=extracellular space" "accessory protein 26A, Accessory gland-specific peptide 26Aa, Acp26a, ovulin, mst355a, Acp26Aab, Accessory gland peptide 26Aa, Acp, Ovulin, mst 355a, CG8982, accessory gland-specific peptide 26Aa, Acp26A, Mst26A, Mst26Aa, msP355a" IPR004315=Male Drosophila accessory gland secretory protein CG8982 16-Dec-15 2015_12 " adult stage | male , pupal stage&&adult stage " male accessory gland

" adult stage | female , adult stage | male " " genital chamber

, adult hemolymph

, male accessory gland secondary cell

, male accessory gland

, male accessory gland main cell

" "viable,fertile" "egg,supernumerary" FBgn0039851 mey morpheyus http://flybase.net/reports/FBgn0039851.html protein_coding_gene "0003383=apical constriction, 0016476=regulation of embryonic cell shape" 0016021=integral component of membrane "CG12063, mey, morpheyus" "IPR001507=Zona pellucida domain, IPR003609=PAN/Apple domain" CG12063 16-Dec-15 2015_12 "WBGene00009541(cutl-17),WBGene00018256(cutl-28)" FBgn0265895 CR44684 http://flybase.net/reports/FBgn0265895.html non_protein_coding_gene CR44684 16-Dec-15 2015_12 FBgn0061072 l(3)S017014a lethal (3) S017014a http://flybase.net/reports/FBgn0061072.html gene 0170/14 16-Dec-15 2015_12 "lethal,recessive" FBgn0035699 CG13300 http://flybase.net/reports/FBgn0035699.html protein_coding_gene CG13300 16-Dec-15 2015_12 lethal FBgn0063597 CS3-2 "Calcineurin suppressor, chromosome 3, group 2" http://flybase.net/reports/FBgn0063597.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020579 anon-59Cf anon-59Cf http://flybase.net/reports/FBgn0020579.html gene 16-Dec-15 2015_12 FBgn0043535 Obp57a Odorant-binding protein 57a http://flybase.net/reports/FBgn0043535.html "FBgn0050141, FBgn0063475" protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "General odorant-binding protein 57a precursor, DmelObp57a, Obp57c, 57a, anon-AE003792.1, unnamed, OBP57a, obp57a, Obp-f, CG30141" IPR006170=Pheromone/general odorant binding protein CG30141 16-Dec-15 2015_12 viable FBgn0023187 Mabfb45 Monoclonal antibody fb45 http://flybase.net/reports/FBgn0023187.html gene MAB fb45 16-Dec-15 2015_12 FBgn0005694 Aef1 Adult enhancer factor 1 http://flybase.net/reports/FBgn0005694.html protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding" 0000122=negative regulation of transcription from RNA polymerase II promoter 0005634=nucleus "CG5683, AEF-1, Adh enhancer factor 1" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG5683 16-Dec-15 2015_12 "YPR015C(),YPR013C()" WBGene00015138(B0310.2) "viable,fertile" FBgn0005366 Va Venae abnormels http://flybase.net/reports/FBgn0005366.html gene Venae abnormeis 16-Dec-15 2015_12 wing vein FBgn0062682 EP1570 EP1570 http://flybase.net/reports/FBgn0062682.html gene EP(X)1570 16-Dec-15 2015_12 FBgn0267460 CR45810 http://flybase.net/reports/FBgn0267460.html non_protein_coding_gene CR45810 16-Dec-15 2015_12 FBgn0259974 Sfp84E Seminal fluid protein 84E http://flybase.net/reports/FBgn0259974.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 84E, CG42484" CG42484 16-Dec-15 2015_12 FBgn0061509 l(2)24Aa lethal (2) 24Aa http://flybase.net/reports/FBgn0061509.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032291 CG17118 http://flybase.net/reports/FBgn0032291.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity 0048813=dendrite morphogenesis 0005634=nucleus IPR007714=Cilia/flagella-associated protein 20/WDR90/C3orf67 CG17118 16-Dec-15 2015_12 "viable,fertile" FBgn0262178 mir-981 mir-981 stem loop http://flybase.net/reports/FBgn0262178.html miRNA_gene "dme-mir-981, CR42885, miR-981" CR42885 16-Dec-15 2015_12 "lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,wing disc,wing,wing margin,1st posterior cell" FBgn0030892 CG7206 http://flybase.net/reports/FBgn0030892.html protein_coding_gene "IPR029060=PIN domain-like, IPR002716=PIN domain" CG7206 16-Dec-15 2015_12 viable FBgn0265939 CR44726 http://flybase.net/reports/FBgn0265939.html non_protein_coding_gene lincRNA.127 CR44726 16-Dec-15 2015_12 FBgn0002453 l(3)SG6 lethal (3) SG6 http://flybase.net/reports/FBgn0002453.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0039118 CG10208 http://flybase.net/reports/FBgn0039118.html protein_coding_gene CT28701 IPR018959=Domain of unknown function DUF1989 CG10208 16-Dec-15 2015_12 "viable,fertile" FBgn0010388 Dro Drosocin http://flybase.net/reports/FBgn0010388.html "FBgn0062947, FBgn0067904" protein_coding_gene "0009617=response to bacterium, 0006952=defense response, 0050829=defense response to Gram-negative bacterium, 0019731=antibacterial humoral response, 0050830=defense response to Gram-positive bacterium, 0042742=defense response to bacterium" 0005576=extracellular region "DIM-15, drc, Drosophila Immune induced molecule 11, Drosophila Immune induced molecule 9, dros, dro, Dro1, Drosophila Immune induced molecule 15, Drosocin, DIM 9, BcDNA:RH31634, Drc, CG10816, IM15, Dros, drosocin, DROC, 143609_at, Drs, Drosocin precursor, DIM 15, DIM 11" CG10816 16-Dec-15 2015_12 viable DRSC07406 K 0.408037513 0.207729541 0.773140263 -0.313391777 2.727205213 0.473020341 FBgn0038258 CG7362 http://flybase.net/reports/FBgn0038258.html protein_coding_gene "0030955=potassium ion binding, 0000287=magnesium ion binding, 0004743=pyruvate kinase activity" "0006909=phagocytosis, 0006096=glycolytic process" "IPR015813=Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR015794=Pyruvate kinase, alpha/beta, IPR001697=Pyruvate kinase, IPR018209=Pyruvate kinase, active site, IPR015793=Pyruvate kinase, barrel, IPR015795=Pyruvate kinase, C-terminal" CG7362 16-Dec-15 2015_12 viable FBgn0259722 CG42376 http://flybase.net/reports/FBgn0259722.html protein_coding_gene 0004129=cytochrome-c oxidase activity 0005739=mitochondrion "IPR003213=Cytochrome c oxidase, subunit VIb" CG42376 16-Dec-15 2015_12 ENSDARG00000069597(si:ch211-258f14.5) YMR244C-A() ENSXETG00000016226(C1orf31) ENSMUSG00000051671(1810063B05Rik) ENSG00000168275(C1orf31) FBgn0030973 CG7332 http://flybase.net/reports/FBgn0030973.html protein_coding_gene "IPR011992=EF-hand domain pair, IPR025257=Domain of unknown function DUF4205" CG7332 16-Dec-15 2015_12 ENSDARG00000028715(zgc:153892) ENSXETG00000020297(Q6NX27_XENTR) ENSMUSG00000026767(Fam188a) ENSG00000148481(FAM188A) viable FBgn0084653 Su(dpp)YE5 Su(dpp)YE5 http://flybase.net/reports/FBgn0084653.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,amnioserosa" FBgn0017550 Rga Regena http://flybase.net/reports/FBgn0017550.html FBgn0010819 protein_coding_gene 0005515=protein binding "0006402=mRNA catabolic process, 0006355=regulation of transcription, DNA-templated, 0007095=mitotic G2 DNA damage checkpoint, 0046331=lateral inhibition, 0017148=negative regulation of translation" "0005634=nucleus, 0005737=cytoplasm, 0030014=CCR4-NOT complex" "regena, CG2161, RGA, CG2138, Not2, NOT2, l(3)03834, not2" IPR007282=NOT2/NOT3/NOT5 CG2161 16-Dec-15 2015_12 WBGene00003825(ntl-2) ENSXETG00000011385(CNOT2) "lethal,viable,fertile,partially lethal - majority die,recessive,visible,lethal - all die before end of larval stage,some die during larval stage,suppressor of variegation,dominant" "terminalia,chaeta,supernumerary" FBgn0266899 CR45359 http://flybase.net/reports/FBgn0266899.html non_protein_coding_gene CR45359 16-Dec-15 2015_12 FBgn0016054 phr6-4 (6-4)-photolyase http://flybase.net/reports/FBgn0016054.html protein_coding_gene 0003914=DNA (6-4) photolyase activity 0006281=DNA repair "D6-4, Dm 64, phr(6-4), CG2488, photolyase, 64PHR, (6-4) photolyase, 6-4 photolyase, (6-4)photolyase, 38D.25" "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR006050=DNA photolyase, N-terminal, IPR005101=Cryptochrome/photolyase FAD-binding domain" CG2488 16-Dec-15 2015_12 "ENSDARG00000019498(cry5),ENSDARG00000045768(cry1a),ENSDARG00000024049(cry3),ENSDARG00000011583,ENSDARG00000069074(cry2a)" YOR386W(PHR1) "ENSXETG00000003913(),ENSXETG00000016951(CRY1)" "ENSMUSG00000068742(Cry2),ENSMUSG00000020038(Cry1)" "ENSG00000121671(CRY2),ENSG00000008405(CRY1)" adult stage && oogenesis stage ovary

viable FBgn0004588 Eig71Ea Ecdysone-induced gene 71Ea http://flybase.net/reports/FBgn0004588.html protein_coding_gene "0007552=metamorphosis, 0042742=defense response to bacterium" 0005576=extracellular region "L71, I, CG16931, gene I, Gene I, gene-I, 71E-Gene-I, L71-1" IPR003475=Insect protein of unknown function CG16931 16-Dec-15 2015_12 viable FBgn0082578 EP917 BEST:RE29262 http://flybase.net/reports/FBgn0082578.html gene BEST:RE29262 16-Dec-15 2015_12 "germline cell,male" FBgn0000884 fs(1)M82 female sterile (1) M82 http://flybase.net/reports/FBgn0000884.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0267731 CR46062 http://flybase.net/reports/FBgn0267731.html non_protein_coding_gene CR46062 16-Dec-15 2015_12 FBgn0082373 EP2031 EP2031 http://flybase.net/reports/FBgn0082373.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0061498 l(2)45Ao lethal (2) 45Ao http://flybase.net/reports/FBgn0061498.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0031998 SLC5A11 Sodium/solute co-transporter-like 5A11 http://flybase.net/reports/FBgn0031998.html protein_coding_gene 0008523=sodium-dependent multivitamin transmembrane transporter activity "0008343=adult feeding behavior, 0055085=transmembrane transport, 0051780=behavioral response to nutrient" 0016020=membrane "NA-dependent multivitamin transporter, CG8451, cupcake, sodium/solute co-transporter-like 5A11, CG8451-PA" "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG8451 16-Dec-15 2015_12 YHL016C(DUR3) WBGene00014092(ZK822.5) "feeding behavior defective,chemical resistant,short lived,viable" FBgn0038165 Task6 TWIK-related acid-sensitive K+ channel 6 http://flybase.net/reports/FBgn0038165.html "FBgn0043907, FBgn0043908, FBgn0043909, FBgn0043910, FBgn0043911, FBgn0043912, FBgn0043913, FBgn0043914, FBgn0043955" protein_coding_gene "0046982=protein heterodimerization activity, 0005267=potassium channel activity" 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "anon-WO0109301.54, anon-WO0109301.56, dTASK-6, Task6, anon-WO0109301.53, anon-WO0109301.55, anon-WO0109301.57, anon-WO0109301.58, CG9637, K2P-TASK6, anon-WO0109301.11, anon-WO0109301.59, anon-WO0109301.60" "IPR013099=Potassium channel domain, IPR003280=Two pore domain potassium channel, IPR003092=Two pore domain potassium channel, TASK family" CG9637 16-Dec-15 2015_12 "ENSDARG00000043466(kcnk3),ENSDARG00000052898(LOC571330)" WBGene00006318(sup-9) ENSXETG00000022828() "ENSMUSG00000049265(Kcnk3),ENSMUSG00000036760(Kcnk9),ENSMUSG00000035238(Kcnk15)" "ENSG00000169427(KCNK9),ENSG00000171303(KCNK3)" "visible,partially lethal - majority die,some die during pupal stage,lethal" mesothoracic tergum FBgn0265346 CR44300 http://flybase.net/reports/FBgn0265346.html non_protein_coding_gene CR44300 16-Dec-15 2015_12 FBgn0027079 Aats-val Valyl-tRNA synthetase http://flybase.net/reports/FBgn0027079.html "FBgn0010542, FBgn0010671, FBgn0033805, FBgn0043789" protein_coding_gene "0002161=aminoacyl-tRNA editing activity, 0004832=valine-tRNA ligase activity, 0005524=ATP binding, 0004818=glutamate-tRNA ligase activity" "0006438=valyl-tRNA aminoacylation, 0022008=neurogenesis" 0005737=cytoplasm "BEST:LD45671, ValRS, l(2)rI255, VRS, CG4062, ld45671, l(2)03531" "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR013155=Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR009008=Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR002303=Valine-tRNA ligase, IPR019499=Valyl-tRNA synthetase, tRNA-binding arm, IPR002300=Aminoacyl-tRNA synthetase, class Ia" CG4062 16-Dec-15 2015_12 ENSDARG00000056717(vars2) YGR094W(VAS1) WBGene00006936(vars-2) ENSXETG00000024076(VARS) ENSMUSG00000007029(Vars) "ENSG00000204394(VARS),ENSG00000096171" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0002815 ms(2)1 male sterile (2) 1 http://flybase.net/reports/FBgn0002815.html gene 16-Dec-15 2015_12 "male sterile,female fertile" spermatozoon FBgn0020654 Mucin-D Mucin-D http://flybase.net/reports/FBgn0020654.html gene "0005576=extracellular region, 0035182=female germline ring canal outer rim, 0045171=intercellular bridge" "Gp90, mucin-D, GP, unnamed, D-mucin, Mucin-D" 16-Dec-15 2015_12 FBgn0002925 ncn nurse cell number http://flybase.net/reports/FBgn0002925.html gene 0048477=oogenesis ncn-I 16-Dec-15 2015_12 "female sterile,tumorigenic" "nurse cell,egg,egg chamber" FBgn0019851 anon-XIII anon-XIII http://flybase.net/reports/FBgn0019851.html gene XIII 16-Dec-15 2015_12 FBgn0041844 E(Sev-CycE)D45 E(Sev-CycE)D45 http://flybase.net/reports/FBgn0041844.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267007 CR45451 http://flybase.net/reports/FBgn0267007.html non_protein_coding_gene CR45451 16-Dec-15 2015_12 FBgn0283462 IMPPP Immune induced molecule prepropeptide http://flybase.net/reports/FBgn0283462.html "FBgn0033835, FBgn0067899, FBgn0067898, FBgn0067896, FBgn0067902" protein_coding_gene "0008063=Toll signaling pathway, 0019731=antibacterial humoral response, 0006959=humoral immune response, 0009617=response to bacterium, 0006952=defense response" "0005615=extracellular space, 0005576=extracellular region" "DIM10, IM8, DIM-12, DIM 12, Immune induced molecule 6, DIM 24 family precursor, DIM-24, DIM 24, Immune induced molecule 10, IM5, immune-induced molecule 10, CG18279, im10, DIM 10, DIM 20, DIM 6, Immune induced molecule 5, DIM12, Immune induced molecule 20, IM6, DIM 5, DIM-10, DIM 8, DIM 13, Immune induced molecule 8, IM20, DIM-13, DIM13, IM10, Immune-induced peptides precursor" CG18279 16-Dec-15 2015_12 FBgn0063365 EP853 BEST:RE60986 http://flybase.net/reports/FBgn0063365.html gene "BEST:RE60986, EP(2)0853, RE60986" 16-Dec-15 2015_12 FBgn0016659 H1 haemolymph protein 1 http://flybase.net/reports/FBgn0016659.html gene 16-Dec-15 2015_12 FBgn0031384 CG4238 http://flybase.net/reports/FBgn0031384.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process "0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" "IPR013761=Sterile alpha motif/pointed domain, IPR000569=HECT domain, IPR013783=Immunoglobulin-like fold, IPR001298=Filamin/ABP280 repeat, IPR014756=Immunoglobulin E-set, IPR017868=Filamin/ABP280 repeat-like, IPR001660=Sterile alpha motif domain" CG4238 16-Dec-15 2015_12 ENSDARG00000021691 ENSXETG00000013271(BC088585.1) ENSMUSG00000042350(1110018G07Rik) ENSG00000119682(KIAA0317) viable FBgn0266588 CR45113 http://flybase.net/reports/FBgn0266588.html non_protein_coding_gene CR45113 16-Dec-15 2015_12 FBgn0038704 CG5316 http://flybase.net/reports/FBgn0038704.html protein_coding_gene "0003684=damaged DNA binding, 0033699=DNA 5'-adenosine monophosphate hydrolase activity" "0000398=mRNA splicing, via spliceosome, 0000012=single strand break repair" 0071011=precatalytic spliceosome "IPR011146=HIT-like domain, IPR019808=Histidine triad, conserved site, IPR001310=Histidine triad (HIT) protein, IPR015880=Zinc finger, C2H2-like, IPR026963=Aprataxin" CG5316 16-Dec-15 2015_12 "viable,fertile" FBgn0051828 CG31828 http://flybase.net/reports/FBgn0051828.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0083150 S(smoDN)2472 Suppressor of smoDN 2472 http://flybase.net/reports/FBgn0083150.html gene 16-Dec-15 2015_12 FBgn0013557 l(3)ry160 lethal (3) ry160 http://flybase.net/reports/FBgn0013557.html gene l(3)160 16-Dec-15 2015_12 "lethal,recessive" FBgn0003968 vao varied outspread http://flybase.net/reports/FBgn0003968.html gene 16-Dec-15 2015_12 "male sterile,recessive,viable,poor,visible,male,eye color defective,body color defective,lethal" "pigment cell,wing" FBgn0266583 Nrt::spi http://flybase.net/reports/FBgn0266583.html engineered_fusion_gene Nrt-Spi 16-Dec-15 2015_12 "photoreceptor,ectopic,somatic clone,eye disc" FBgn0265060 CR44171 http://flybase.net/reports/FBgn0265060.html non_protein_coding_gene CG44171 CR44171 16-Dec-15 2015_12 FBgn0027238 l(1)G0277 lethal (1) G0277 http://flybase.net/reports/FBgn0027238.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0038008 CG3942 http://flybase.net/reports/FBgn0038008.html protein_coding_gene "2001070=starch binding, 0008081=phosphoric diester hydrolase activity" 0006629=lipid metabolic process "IPR030395=Glycerophosphodiester phosphodiesterase domain, IPR013783=Immunoglobulin-like fold, IPR002044=Carbohydrate binding module family 20, IPR013784=Carbohydrate-binding-like fold, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG3942 16-Dec-15 2015_12 "WBGene00011511(T05H10.7),WBGene00019612(K10B3.6)" viable FBgn0065048 snoRNA:U3:54Aa snoRNA:U3:54Aa http://flybase.net/reports/FBgn0065048.html FBgn0053921 snoRNA_gene 0030556=rRNA modification guide activity 0005730=nucleolus "Dm-818, snoRNA U3, 54A U3 snoRNA, DmU3a(U3), U3 snoRNA, CR33921, U3-snoRNA" CR33921 16-Dec-15 2015_12 FBgn0010947 l(3)10585 lethal (3) 10585 http://flybase.net/reports/FBgn0010947.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0066322 zlo zloday http://flybase.net/reports/FBgn0066322.html gene "0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 memory defective FBgn0000044 Act57B Actin 57B http://flybase.net/reports/FBgn0000044.html "FBgn0019861, FBgn0050294, FBgn0065030" protein_coding_gene 0005200=structural constituent of cytoskeleton "0051297=centrosome organization, 0000281=mitotic cytokinesis, 0007507=heart development, 0051533=positive regulation of NFAT protein import into nucleus, 0050807=regulation of synapse organization, 0098529=neuromuscular junction development, skeletal muscle fiber, 0007010=cytoskeleton organization" "0005884=actin filament, 0005886=plasma membrane, 0005875=microtubule associated complex" "Act57A, Act57b, anon-EST:CL2c12, Actin57B, actin57B, Actin 57B, act57A, actin, chr2R:16452771..16452966, BEST:RE38067, Act57, actin 57B, act 57A, F-actin, act57b, CG30294, act57B, Actin, T10, M, C, CG10067" "IPR004000=Actin family, IPR020902=Actin/actin-like conserved site, IPR004001=Actin, conserved site" CG10067 16-Dec-15 2015_12 YFL039C(ACT1) " larval stage , embryonic stage | late , embryonic stage " " embryonic/larval somatic muscle

, mesoderm

, larval muscle system

, pharyngeal muscle

" "lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" germline cyst DRSC04042 I -0.96138894 -1.990773338 0.092595138 -1.057395086 -0.488582698 1.177050775 FBgn0010173 RpA-70 Replication Protein A 70 http://flybase.net/reports/FBgn0010173.html protein_coding_gene 0003697=single-stranded DNA binding "0048812=neuron projection morphogenesis, 0007095=mitotic G2 DNA damage checkpoint, 0006310=DNA recombination, 0006260=DNA replication, 0007052=mitotic spindle organization, 0006261=DNA-dependent DNA replication, 0006281=DNA repair" "0005662=DNA replication factor A complex, 0005875=microtubule associated complex, 0005634=nucleus" "RpA1, dRP-A, CG9633, RPA1, dmrpa1, RP-A, Drosophila Replication Protein A, RPA70, RPA 70, Single stranded-binding protein 70, i164, RPA, RpA70, D-RPA70, DmRPA, Ssb-70, D-SSB, Rpa-70, DRP-A, RPA 70 kDa" "IPR004591=Replication factor A protein 1, IPR007199=Replication factor-A protein 1, N-terminal, IPR004365=OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR013955=Replication factor A, C-terminal, IPR012340=Nucleic acid-binding, OB-fold" CG9633 16-Dec-15 2015_12 ENSDARG00000003938(rpa1) YAR007C(RFA1) WBGene00017546(rpa-1) ENSXETG00000013538(rpa1) ENSMUSG00000000751(Rpa1) ENSG00000132383(RPA1) embryonic stage "viable,fertile,lethal,partially lethal - majority die,visible,neuroanatomy defective" "mesothoracic tergum,lamina anlage,medulla anlage,larval optic anlage,larval outer optic anlage,somatic clone" FBgn0020417 I-element\gag I element gag http://flybase.net/reports/FBgn0020417.html transposable_element_gene "unnamed, I factor ORF1, ORF1, I factor Gag, IF ORF1, I-element ORF1, ORF1p" 16-Dec-15 2015_12 FBgn0084041 CG41481 http://flybase.net/reports/FBgn0084041.html FBan0041481 protein_coding_gene 16-Dec-15 2015_12 FBgn0011115 l(1)Q76 lethal (1) Q76 http://flybase.net/reports/FBgn0011115.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0001099 gdl gonadal http://flybase.net/reports/FBgn0001099.html "FBgn0053088, FBgn0053756" protein_coding_gene "0007283=spermatogenesis, 0048477=oogenesis" "CG7268, CG33756, CG33088" IPR010849=DiGeorge syndrome critical 6 CG33756 16-Dec-15 2015_12 ENSDARG00000005500(zgc:101841) ENSXETG00000021658() ENSMUSG00000003531(Dgcr6) "ENSG00000183628(DGCR6),ENSG00000128185(DGCR6L)" " adult stage | male , adult stage | female " " oocyte

, nurse cell

, testis

" FBgn0053784 CG33784 http://flybase.net/reports/FBgn0053784.html protein_coding_gene HDC12790 IPR010512=Protein of unknown function DUF1091 CG33784 16-Dec-15 2015_12 FBgn0019666 p56 p56 http://flybase.net/reports/FBgn0019666.html gene 16-Dec-15 2015_12 FBgn0052713 CG32713 http://flybase.net/reports/FBgn0052713.html protein_coding_gene "IPR000626=Ubiquitin domain, IPR015496=Ubiquilin, IPR029071=Ubiquitin-related domain" CG32713 16-Dec-15 2015_12 FBgn0052412 QC Glutaminyl cyclase http://flybase.net/reports/FBgn0052412.html FBgn0035646 protein_coding_gene 0016603=glutaminyl-peptide cyclotransferase activity "0017186=peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase" 0005576=extracellular region "CG10487, CG32412, DromeQC" IPR007484=Peptidase M28 CG32412 16-Dec-15 2015_12 YFR018C() WBGene00010418(H27A22.1) "viable,visible" "chaeta,supernumerary" FBgn0015255 M(2)201 M(2)201 http://flybase.net/reports/FBgn0015255.html gene 16-Dec-15 2015_12 macrochaeta FBgn0039013 CG4813 http://flybase.net/reports/FBgn0039013.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0005737=cytoplasm "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG4813 16-Dec-15 2015_12 "ENSDARG00000060929(zgc:153254),ENSDARG00000060479" ENSXETG00000001054(TEgg019o12.1) ENSMUSG00000028677(Rnf220) ENSG00000187147(RNF220) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001756 l(1)M4 lethal (1) M4 http://flybase.net/reports/FBgn0001756.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005195 l(2)Sp9b lethal (2) Sp9b http://flybase.net/reports/FBgn0005195.html gene 16-Dec-15 2015_12 lethal FBgn0084369 E-2fb Enhancer on chromosome 2-complementation group fb http://flybase.net/reports/FBgn0084369.html gene E-2f 16-Dec-15 2015_12 FBgn0084423 l(3)S024833 l(3)S024833 http://flybase.net/reports/FBgn0084423.html gene 16-Dec-15 2015_12 FBgn0005495 l(1)tsG1 lethal (1) tsG1 http://flybase.net/reports/FBgn0005495.html gene 16-Dec-15 2015_12 "lethal,cold sensitive" FBgn0025781 Cdc16 Cell division cycle 16 ortholog http://flybase.net/reports/FBgn0025781.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0090302=APC-Cdc20 complex activity" "0007067=mitotic nuclear division, 0045842=positive regulation of mitotic metaphase/anaphase transition, 0022008=neurogenesis, 0000278=mitotic cell cycle, 0030071=regulation of mitotic metaphase/anaphase transition" 0005680=anaphase-promoting complex "CDC16, Dmcdc16, APC6, Cdc16, Apc6, CG6759, cdc16" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1" CG6759 16-Dec-15 2015_12 ENSDARG00000055470(cdc16) YKL022C(CDC16) ENSG00000130177(CDC16) "increased cell death,mitotic cell cycle defective,lethal,neuroanatomy defective,viable,visible,melanotic mass phenotype" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,melanotic mass | third instar larval stage" FBgn0060632 l(3)S085208 lethal (3) S085208 http://flybase.net/reports/FBgn0060632.html gene 0852/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0000850 fs(1)M39 female sterile (1) M39 http://flybase.net/reports/FBgn0000850.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0002605 M(2)56F Minute (2) 56F http://flybase.net/reports/FBgn0002605.html gene "RpS18, M(2)173, l(2)56Fc" 16-Dec-15 2015_12 "visible,dominant,lethal,recessive,viable,Minute" macrochaeta FBgn0001011 fs(3)A2 female sterile (3) A2 http://flybase.net/reports/FBgn0001011.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0065605 l(2)SH0850 lethal (2) SH0850 http://flybase.net/reports/FBgn0065605.html gene l(2)SH2 0850 16-Dec-15 2015_12 "lethal,recessive" FBgn0004055 uzip unzipped http://flybase.net/reports/FBgn0004055.html protein_coding_gene "0007409=axonogenesis, 0007413=axonal fasciculation, 0007411=axon guidance" "0005886=plasma membrane, 0016021=integral component of membrane" "not-zipper, CG3533, Unzipped, zip, zipper, nzip" CG3533 16-Dec-15 2015_12 viable FBgn0260356 GSd236 http://flybase.net/reports/FBgn0260356.html gene 16-Dec-15 2015_12 lethal "ventral nerve cord,longitudinal connective" FBgn0028517 CG18478 http://flybase.net/reports/FBgn0028517.html FBgn0032569 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "DS07108.5, BG:DS07108.5, SPH157" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG18478 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" FBgn0259950 CG42460 http://flybase.net/reports/FBgn0259950.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG42460 16-Dec-15 2015_12 FBgn0043784 Bari1\ORF ORF http://flybase.net/reports/FBgn0043784.html transposable_element_gene "0003677=DNA binding, 0004803=transposase activity" "0015074=DNA integration, 0006313=transposition, DNA-mediated" Bari-1 "IPR009057=Homeodomain-like, IPR002492=Transposase, Tc1-like" 16-Dec-15 2015_12 FBgn0000603 E(var)302 Enhancer of variegation 302 http://flybase.net/reports/FBgn0000603.html gene En(var)302 16-Dec-15 2015_12 "viable,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0261636 CR42719 http://flybase.net/reports/FBgn0261636.html "FBgn0052345, FBgn0046990" non_protein_coding_gene "CG32345, CG42719, BcDNA:SD03580" CR42719 16-Dec-15 2015_12 FBgn0052243 CG32243 http://flybase.net/reports/FBgn0052243.html FBgn0063061 protein_coding_gene BcDNA:RE12890 CG32243 16-Dec-15 2015_12 viable DRSC08105 I 1.587919693 0.34373819 -0.155439225 0.627376982 0.133158093 1.436929838 FBgn0030465 CG15743 http://flybase.net/reports/FBgn0030465.html protein_coding_gene "0008934=inositol monophosphate 1-phosphatase activity, 0004441=inositol-1,4-bisphosphate 1-phosphatase activity" "0007165=signal transduction, 0046854=phosphatidylinositol phosphorylation, 0016311=dephosphorylation, 0006796=phosphate-containing compound metabolic process, 0006661=phosphatidylinositol biosynthetic process" "0012505=endomembrane system, 0005737=cytoplasm" "IPR020550=Inositol monophosphatase, conserved site, IPR000760=Inositol monophosphatase" CG15743 16-Dec-15 2015_12 ENSDARG00000058114(zgc:123256) WBGene00012390(Y6B3B.5) ENSXETG00000005659(impa3) ENSMUSG00000066324(Impad1) ENSG00000104331(IMPAD1) "viable,fertile" FBgn0259381 C500 http://flybase.net/reports/FBgn0259381.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0037197 CG13239 http://flybase.net/reports/FBgn0037197.html protein_coding_gene CG13239 16-Dec-15 2015_12 viable FBgn0033862 CG6209 http://flybase.net/reports/FBgn0033862.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" mst101(2) CG6209 16-Dec-15 2015_12 viable DRSC06968 K 0.256120799 0.14358835 0.090447844 -0.047401748 2.115177604 0.965855701 FBgn0038073 CG14395 http://flybase.net/reports/FBgn0038073.html protein_coding_gene CG14395 16-Dec-15 2015_12 viable FBgn0083266 E(smoDN)461 Enhancer of smoDN 461 http://flybase.net/reports/FBgn0083266.html gene 16-Dec-15 2015_12 FBgn0086300 lent lengthy http://flybase.net/reports/FBgn0086300.html gene "0048813=dendrite morphogenesis, 0046847=filopodium assembly" 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" "dendrite | larval stage,dendrite & filopodium & larva,dorsal multidendritic neuron ddaA & filopodium" FBgn0019693 l(3)68Fh lethal (3) 68Fh http://flybase.net/reports/FBgn0019693.html gene l(3)68Fc 16-Dec-15 2015_12 lethal FBgn0267238 CR45678 http://flybase.net/reports/FBgn0267238.html non_protein_coding_gene lincRNA.628 CR45678 16-Dec-15 2015_12 FBgn0060329 l(3)S146315 lethal (3) S146315 http://flybase.net/reports/FBgn0060329.html gene 1463/15 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0051382 tRNA:CR31382 transfer RNA:CR31382 http://flybase.net/reports/FBgn0051382.html FBgn0060256 tRNA_gene 0033458=GAC codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:D:GTC:AE002708-b, AE002708.trna31-AspGTC, chr3R.trna37-AspGTC, tRNA[[Asp]], CR31382, tRNA[Asp-GTC]" CR31382 16-Dec-15 2015_12 FBgn0011288 Snap25 Synaptosomal-associated protein 25kDa http://flybase.net/reports/FBgn0011288.html "FBan0040452, FBgn0039960, FBgn0039996" protein_coding_gene "0000149=SNARE binding, 0005515=protein binding, 0005484=SNAP receptor activity" "0007274=neuromuscular synaptic transmission, 0048172=regulation of short-term neuronal synaptic plasticity, 0007269=neurotransmitter secretion, 0006906=vesicle fusion, 0031629=synaptic vesicle fusion to presynaptic membrane, 0016081=synaptic vesicle docking, 0006893=Golgi to plasma membrane transport, 0048489=synaptic vesicle transport, 0016192=vesicle-mediated transport, 0016082=synaptic vesicle priming, 0007268=synaptic transmission" "0043195=terminal bouton, 0005737=cytoplasm, 0005886=plasma membrane, 0016020=membrane, 0031201=SNARE complex, 0031083=BLOC-1 complex, 0045202=synapse" "SNAP25, synaptosomal-associated protein 25, Synapse protein 25, CG17884, CG40452, SNAP-25, snap-25, CG17676, snp25" "IPR000928=SNAP-25, IPR000727=Target SNARE coiled-coil homology domain" CG40452 16-Dec-15 2015_12 "ENSDARG00000020609(snap25a),ENSDARG00000040965(zgc:101731),ENSDARG00000058117(snap25b)" WBGene00004364(ric-4) ENSXETG00000015096(snap25) ENSMUSG00000027273(Snap25) ENSG00000132639(SNAP25) " adult stage , larval stage , embryonic stage | stage>=14 " " optic lobe

, abdominal neuromere

, subesophageal ganglion

, thoracico-abdominal ganglion

, ventral nerve cord

, neuron

, adult brain

" " embryonic stage | stage >=14 , embryonic stage | stage 16 " " ventral nerve cord

, chordotonal organ

" "paralytic,heat sensitive,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal,viable,neurophysiology defective,temperature conditional,neuroanatomy defective" "neuromuscular junction,neuromuscular junction | temperature conditional1-16),t-bar" FBgn0044033 Mod(rst)K35 Mod(rst)K35 http://flybase.net/reports/FBgn0044033.html gene 0001745=compound eye morphogenesis K35 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0005081 fs(2)OW805 female sterile (2) OW805 http://flybase.net/reports/FBgn0005081.html gene 16-Dec-15 2015_12 FBgn0038924 CG6028 http://flybase.net/reports/FBgn0038924.html protein_coding_gene 0003824=catalytic activity 0008152=metabolic process "IPR011234=Fumarylacetoacetase, C-terminal-related" CG6028 16-Dec-15 2015_12 ENSDARG00000020169(zgc:85683) ENSXETG00000004339(fahd2a) ENSMUSG00000027371(Fahd2a) "ENSG00000115042(FAHD2A),ENSG00000144199(FAHD2B)" FBgn0069223 gl(2R)2-11 gl(2R)2-11 http://flybase.net/reports/FBgn0069223.html gene 0009952=anterior/posterior pattern specification 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic abdominal segment,germline clone,maternal effect,embryo,posterior" FBgn0267771 CR46102 http://flybase.net/reports/FBgn0267771.html non_protein_coding_gene CR46102 16-Dec-15 2015_12 FBgn0065933 l(2)SH0130 lethal (2) SH0130 http://flybase.net/reports/FBgn0065933.html gene l(2)SH2 0130 16-Dec-15 2015_12 "lethal,recessive" FBgn0260866 dnr1 defense repressor 1 http://flybase.net/reports/FBgn0260866.html "FBgn0034738, FBgn0084288" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0030431=sleep, 0002814=negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0016567=protein ubiquitination, 0006955=immune response, 0007476=imaginal disc-derived wing morphogenesis" 0005856=cytoskeleton "DNR1, Defense repressor I, Dnr1, CG12489, defense repressor 1, dnr1, Defense repressor 1" "IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000299=FERM domain, IPR001841=Zinc finger, RING-type, IPR029071=Ubiquitin-related domain, IPR018979=FERM, N-terminal" CG12489 16-Dec-15 2015_12 "ENSDARG00000008859(mylipa),ENSDARG00000055118(mylipb)" ENSXETG00000015431(mylip) FBgn0035592 CG10674 http://flybase.net/reports/FBgn0035592.html protein_coding_gene IPR005351=Uncharacterised protein family UPF0139 CG10674 16-Dec-15 2015_12 ENSDARG00000025554(zgc:73111) WBGene00019607(K10B2.4) ENSXETG00000025826(C19orf56) ENSMUSG00000059355(BC056474) ENSG00000105583(C19orf56) "viable,fertile" FBgn0052536 CG32536 http://flybase.net/reports/FBgn0052536.html FBgn0031009 protein_coding_gene CG8020 IPR017025=Cancer-associated antigen RCAS1 CG32536 16-Dec-15 2015_12 DRSC20074 E 0.021298851 -0.090543383 1.510196946 0.503022244 0.024750045 -0.043207404 FBgn0034069 CG8401 http://flybase.net/reports/FBgn0034069.html protein_coding_gene CG8401 16-Dec-15 2015_12 viable FBgn0267732 CR46063 http://flybase.net/reports/FBgn0267732.html non_protein_coding_gene CR46063 16-Dec-15 2015_12 FBgn0259398 C909 http://flybase.net/reports/FBgn0259398.html gene 16-Dec-15 2015_12 visible wing vein FBgn0267427 CR45780 http://flybase.net/reports/FBgn0267427.html pseudogene_attribute CR45780 16-Dec-15 2015_12 FBgn0027582 CG6230 http://flybase.net/reports/FBgn0027582.html protein_coding_gene "0015662=ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, 0000166=nucleotide binding, 0046872=metal ion binding" 0006812=cation transport "0012505=endomembrane system, 0016021=integral component of membrane" "dCOD1, BcDNA:GH06032" "IPR001757=P-type ATPase, IPR006544=P-type ATPase, subfamily V, IPR023214=HAD-like domain, IPR018303=P-type ATPase, phosphorylation site, IPR008250=P-type ATPase, A domain, IPR023299=P-type ATPase, cytoplasmic domain N" CG6230 16-Dec-15 2015_12 ENSDARG00000029931(LOC100329877) YEL031W(SPF1) WBGene00007514(C10C6.6) ENSXETG00000000635(ATP13A1) ENSMUSG00000031862(Atp13a1) ENSG00000105726(ATP13A1) "viable,visible" trichogen cell FBgn0036210 CG14130 http://flybase.net/reports/FBgn0036210.html protein_coding_gene 0006631=fatty acid metabolic process 0005739=mitochondrion IPR027450=Alpha-ketoglutarate-dependent dioxygenase AlkB-like CG14130 16-Dec-15 2015_12 ENSDARG00000037906(alkbh7) WBGene00012920(Y46G5A.35) ENSXETG00000005578(ALKBH7) ENSMUSG00000002661(Alkbh7) ENSG00000125652(ALKBH7) viable FBgn0038519 Prx3 Peroxiredoxin 3 http://flybase.net/reports/FBgn0038519.html protein_coding_gene "0004601=peroxidase activity, 0008379=thioredoxin peroxidase activity, 0016209=antioxidant activity" "0045454=cell redox homeostasis, 0042744=hydrogen peroxide catabolic process, 0008340=determination of adult lifespan, 0043066=negative regulation of apoptotic process, 0055114=oxidation-reduction process, 0006909=phagocytosis" 0005739=mitochondrion "Prx5037, DPx5037, dPrx3, peroxiredoxin 5037, mTPx, Peroxiredoxin 5037, peroxiredoxin 3, CG5826, mtTPx, thioredoxin-peroxidase-3, DPx-5037, Thioredoxin peroxidase 3, mitochondrial peroxiredoxin" "IPR019479=Peroxiredoxin, C-terminal, IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336=Thioredoxin-like fold" CG5826 16-Dec-15 2015_12 ENSDARG00000032102(prdx3) ENSXETG00000010229(prdx3) ENSMUSG00000024997(Prdx3) ENSG00000165672(PRDX3) "stress response defective,increased cell death,viable" FBgn0039194 CG13614 http://flybase.net/reports/FBgn0039194.html protein_coding_gene IPR006631=Protein of unknown function DM4/12 CG13614 16-Dec-15 2015_12 viable FBgn0004705 l(2)56Fg lethal (2) 56Fg http://flybase.net/reports/FBgn0004705.html gene l(2)56F 16-Dec-15 2015_12 lethal FBgn0086420 l(3)CHd lethal (3) CHd http://flybase.net/reports/FBgn0086420.html gene complementation group 6 16-Dec-15 2015_12 "lethal,recessive" FBgn0003242 Roof Roof http://flybase.net/reports/FBgn0003242.html gene Rf 16-Dec-15 2015_12 wing FBgn0267754 CR46085 http://flybase.net/reports/FBgn0267754.html non_protein_coding_gene CR46085 16-Dec-15 2015_12 FBgn0061038 l(3)S023837b lethal (3) S023837b http://flybase.net/reports/FBgn0061038.html gene 0238/37 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0264662 spikes spikes http://flybase.net/reports/FBgn0264662.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0034398 CG15098 http://flybase.net/reports/FBgn0034398.html protein_coding_gene dmCG15098 CG15098 16-Dec-15 2015_12 viable DRSC06527 E -0.806457665 -1.413043159 -0.209431783 -1.526684042 -0.834180608 0.54635129 FBgn0026076 UBL3 UBL3 http://flybase.net/reports/FBgn0026076.html protein_coding_gene "CG9038, HCG-1, MUB, Ubiquitin-like 3, Ubl3" "IPR000626=Ubiquitin domain, IPR029071=Ubiquitin-related domain" CG9038 16-Dec-15 2015_12 lethal FBgn0021825 DCTN2-p50 "Dynactin 2, p50 subunit" http://flybase.net/reports/FBgn0021825.html FBgn0033338 protein_coding_gene "0051028=mRNA transport, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 2001019=positive regulation of retrograde axon cargo transport, 0051642=centrosome localization, 0007051=spindle organization, 0007018=microtubule-based movement, 0022008=neurogenesis, 0008283=cell proliferation" "0005869=dynactin complex, 0031982=vesicle, 0005739=mitochondrion" "dDyn, P50, p50, p50/Dmn, p50/dynamitin, p50/Dynamitin, l(2)k16218, Dmn, dynamitin, Dynamitin, DMN, l(2)k16109, dmn, p50-dynamitin, p50[Dmn], CG8269, dyna, p50 dynamitin" IPR028133=Dynamitin CG8269 16-Dec-15 2015_12 ENSDARG00000031388(dctn2) WBGene00001018(dnc-2) ENSXETG00000006234(dctn2) ENSMUSG00000025410(Dctn2) ENSG00000175203(DCTN2) "lethal,recessive,viable,fertile,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte,germline clone,stage S9 oocyte & nucleus,dorsal appendage,embryonic/larval nervous system,oocyte & nucleusmat.ë±Tub67C.THsimVP16,embryonic/larval neuroblast,ganglion mother cell" FBgn0013622 l(3)neo12 lethal (3) neo12 http://flybase.net/reports/FBgn0013622.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034750 CG3732 http://flybase.net/reports/FBgn0034750.html protein_coding_gene 0008270=zinc ion binding "IPR001876=Zinc finger, RanBP2-type, IPR017337=Uncharacterised conserved protein UCP037956, zinc finger Ran-binding" CG3732 16-Dec-15 2015_12 ENSDARG00000044332(zranb2) WBGene00021295(Y25C1A.8) ENSXETG00000024108(ZRANB2) ENSMUSG00000028180(Zranb2) ENSG00000132485(ZRANB2) FBgn0264982 CR44133 http://flybase.net/reports/FBgn0264982.html non_protein_coding_gene CR44133 16-Dec-15 2015_12 FBgn0065344 l(2)SH1821 lethal (2) SH1821 http://flybase.net/reports/FBgn0065344.html gene l(2)SH2 1821 16-Dec-15 2015_12 "lethal,recessive" FBgn0000860 fs(1)M54 female sterile (1) M54 http://flybase.net/reports/FBgn0000860.html gene 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0015231 God Godzilla http://flybase.net/reports/FBgn0015231.html gene "0007348=regulation of syncytial blastoderm mitotic cell cycle, 0008595=anterior/posterior axis specification, embryo, 0008586=imaginal disc-derived wing vein morphogenesis" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "wing vein,embryonic abdomen,maternal effect" FBgn0031775 CG9150 http://flybase.net/reports/FBgn0031775.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002198=Short-chain dehydrogenase/reductase SDR" CG9150 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) viable FBgn0032345 CG14921 http://flybase.net/reports/FBgn0032345.html protein_coding_gene 0007605=sensory perception of sound "IPR007052=CS domain, IPR008978=HSP20-like chaperone" CG14921 16-Dec-15 2015_12 ENSG00000128845 "viable,auditory perception defective,neurophysiology defective" FBgn0004697 wapm wings apart mimic http://flybase.net/reports/FBgn0004697.html gene wings-apart mimic 16-Dec-15 2015_12 "viable,female fertile" wing FBgn0003666 taw tawny http://flybase.net/reports/FBgn0003666.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile,body color defective" "adult head,adult thorax,adult abdomen,wing,tergite,female" FBgn0041709 yellow-g yellow-g http://flybase.net/reports/FBgn0041709.html FBgn0035327 protein_coding_gene 0016853=isomerase activity "0048067=cuticle pigmentation, 0042438=melanin biosynthetic process" 0005576=extracellular region "g, CG5717, yell-g" "IPR011044=Quinoprotein amine dehydrogenase, beta chain-like, IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG5717 16-Dec-15 2015_12 "female sterile,male fertile,viable,visible" "chorion,stage S14 oocyte & vitelline membrane,trichogen cell" FBgn0031267 Ipk2 Ipk2 http://flybase.net/reports/FBgn0031267.html protein_coding_gene "0047326=inositol tetrakisphosphate 5-kinase activity, 0008440=inositol-1,4,5-trisphosphate 3-kinase activity, 0000823=inositol-1,4,5-trisphosphate 6-kinase activity" "0046427=positive regulation of JAK-STAT cascade, 0032958=inositol phosphate biosynthetic process" 0005654=nucleoplasm "CG13688, dmIpk2" IPR005522=Inositol polyphosphate kinase CG13688 16-Dec-15 2015_12 ENSDARG00000029291(zgc:158331) WBGene00014081(ZK795.1) ENSXETG00000005113(IPMK) ENSMUSG00000060733(Ipmk) ENSG00000151151(IPMK) viable FBgn0039441 TwdlN TweedleN http://flybase.net/reports/FBgn0039441.html "FBgn0047152, FBgn0064870" protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix "BcDNA:RE20092, chr3R:22457526..22457631, BcDNA:RE59605, CG5476" IPR004145=Domain of unknown function DUF243 CG5476 16-Dec-15 2015_12 viable FBgn0026221 l(3)04704a lethal (3) 04704a http://flybase.net/reports/FBgn0026221.html gene l(3)04704 16-Dec-15 2015_12 lethal FBgn0261283 SREBP Sterol regulatory element binding protein http://flybase.net/reports/FBgn0261283.html "FBgn0015234, FBgn0063456, FBgn0260652" protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0055089=fatty acid homeostasis, 0006633=fatty acid biosynthetic process, 0006909=phagocytosis, 0045893=positive regulation of transcription, DNA-templated, 0042304=regulation of fatty acid biosynthetic process, 1903146=regulation of mitochondrion degradation, 0032933=SREBP signaling pathway, 0000902=cell morphogenesis" "0005634=nucleus, 0016020=membrane, 0005789=endoplasmic reticulum membrane, 0031965=nuclear membrane" "HlH106, dSREBP, srebp, sterol regulatory element-binding protein, HLH106, Drosophila sterol regulatory element binding protein, dsrebp, dSrebp, transcription factor Sterol regulatory element binding protein, CG8522, Sterol regulatory element-binding protein, lethal (3) 76BDw, SREBF1, l(3)76BDw, sterol-responsive element-binding protein, Srebp, Helix loop helix protein 106, SREBP, Sterol Regulatory Element Binding Protein" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG8522 16-Dec-15 2015_12 ENSDARG00000063438(srebf2) WBGene00004735(sbp-1) ENSXETG00000017449(SREBF2) "ENSMUSG00000020538(Srebf1),ENSMUSG00000022463(Srebf2)" "ENSG00000072310(SREBF1),ENSG00000198911(SREBF2)" embryonic stage -- adult stage DRSC11182 EK -0.799301338 0.365729695 2.730670112 -1.900429543 -2.127117432 -1.669485193 FBgn0032668 CG17681 http://flybase.net/reports/FBgn0032668.html protein_coding_gene 0008080=N-acetyltransferase activity "IPR013653=FR47-like, IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG17681 16-Dec-15 2015_12 ENSDARG00000051954(LOC799646) "ENSG00000166840(GLYATL1),ENSG00000203972(GLYATL3),ENSG00000156689(GLYATL2),ENSG00000149124(GLYAT)" viable DRSC02632 K -0.181148511 -0.40662878 -0.950649978 0.058977011 -1.533088565 -0.629538505 FBgn0033879 CG6543 http://flybase.net/reports/FBgn0033879.html FBgn0033878 protein_coding_gene 0004300=enoyl-CoA hydratase activity 0006635=fatty acid beta-oxidation "0005875=microtubule associated complex, 0005759=mitochondrial matrix, 0005811=lipid particle, 0005739=mitochondrion" "Echs1, CG18645" "IPR018376=Enoyl-CoA hydratase/isomerase, conserved site, IPR014748=Crontonase, C-terminal, IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily" CG6543 16-Dec-15 2015_12 ENSDARG00000001578(echs1) WBGene00001155(ech-6) ENSMUSG00000025465(Echs1) ENSG00000127884(ECHS1) "viable,fertile,immune response defective" FBgn0061048 l(3)S023447 lethal (3) S023447 http://flybase.net/reports/FBgn0061048.html gene 0234/47 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0003635 Su(var)330 Suppressor of variegation 330 http://flybase.net/reports/FBgn0003635.html gene 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant" FBgn0264562 Hr4 Hr4 http://flybase.net/reports/FBgn0264562.html "FBgn0043372, FBgn0026087, FBgn0023546, FBgn0263775, FBgn0260432" protein_coding_gene "0008270=zinc ion binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0003707=steroid hormone receptor activity" "0040007=growth, 0043401=steroid hormone mediated signaling pathway, 0030518=intracellular steroid hormone receptor signaling pathway, 0006355=regulation of transcription, DNA-templated, 0007552=metamorphosis, 0035073=pupariation, 0048638=regulation of developmental growth, 0071456=cellular response to hypoxia" 0005634=nucleus "EP1232, DHR4, NR6A2, CG42527, EG:BACH61I5.1, CG43692, CG3600, CG43934, null, CG16902, GRF, EP(X)1232, EG:133E12.2" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR024767=Pre-mRNA-splicing factor 38, C-terminal, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG43934 16-Dec-15 2015_12 DRSC18599 E -0.222993089 -1.247564109 -0.904588725 -3.012265174 0.202447379 0.984270182 FBgn0266512 s-484 http://flybase.net/reports/FBgn0266512.html gene 16-Dec-15 2015_12 FBgn0262031 CR42842 http://flybase.net/reports/FBgn0262031.html pseudogene_attribute CR42842 16-Dec-15 2015_12 FBgn0086553 MRE22 mRNA-like ncRNA in embryogenesis 22 http://flybase.net/reports/FBgn0086553.html non_protein_coding_gene LD33458 16-Dec-15 2015_12 FBgn0053217 CG33217 http://flybase.net/reports/FBgn0053217.html "FBan0033217, FBgn0063058" protein_coding_gene BcDNA:RE15216 IPR016024=Armadillo-type fold CG33217 16-Dec-15 2015_12 ENSXETG00000017229(PELP1) FBgn0013496 l(1)14Ae lethal (1) 14Ae http://flybase.net/reports/FBgn0013496.html gene "l(1)13Fh, I, l(1)I" 16-Dec-15 2015_12 "lethal,recessive" FBgn0039419 CG12290 http://flybase.net/reports/FBgn0039419.html "FBgn0046528, FBgn0046530" protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.50, lincRNA.S7704, anon-WO0170980.49" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG12290 16-Dec-15 2015_12 viable FBgn0082185 l(3)SzB93Ba lethal (3) SzB93Ba http://flybase.net/reports/FBgn0082185.html gene 16-Dec-15 2015_12 lethal FBgn0260456 CG4806 http://flybase.net/reports/FBgn0260456.html FBgn0035048 protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" 0022008=neurogenesis cg4806 "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG4806 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0037026 CG3634 http://flybase.net/reports/FBgn0037026.html protein_coding_gene IPR007311=ST7 CG3634 16-Dec-15 2015_12 ENSDARG00000032603(st7l) WBGene00008686(F11A10.5) ENSXETG00000021764(st7) "ENSMUSG00000029534(St7),ENSMUSG00000045576(St7l)" "ENSG00000004866(ST7),ENSG00000007341(ST7L)" viable DRSC11747 K 0.946812598 0.626548924 -0.342703977 0.242481315 1.754114206 1.217061446 FBgn0086785 Vps36 Vacuolar protein sorting 36 http://flybase.net/reports/FBgn0086785.html "FBgn0036375, FBgn0024559" protein_coding_gene "0043130=ubiquitin binding, 0032266=phosphatidylinositol-3-phosphate binding, 0003730=mRNA 3'-UTR binding" "0042981=regulation of apoptotic process, 0008593=regulation of Notch signaling pathway, 0008283=cell proliferation, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0007224=smoothened signaling pathway" "0000814=ESCRT II complex, 0005768=endosome" "CG10711, l(3)L5212, lethal (3) L5212, Vps36, vps36" "IPR007286=EAP30, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR021648=Vacuolar protein sorting protein 36, GLUE domain" CG10711 16-Dec-15 2015_12 ENSDARG00000057021(vps36) WBGene00008919(vps-36) ENSXETG00000020707(vps36) ENSMUSG00000031479(Vps36) ENSG00000136100(VPS36) DRSC09785 I 1.744984239 -0.254723909 0.871794262 0.345305041 0.324132878 0.13887001 FBgn0004223 l(3)84Fk lethal (3) 84Fk http://flybase.net/reports/FBgn0004223.html gene 16-Dec-15 2015_12 lethal FBgn0032878 CG9316 http://flybase.net/reports/FBgn0032878.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "38E.9, FBXL10" CG9316 16-Dec-15 2015_12 viable FBgn0005073 fs(2)OW214 female sterile (2) OW214 http://flybase.net/reports/FBgn0005073.html gene 16-Dec-15 2015_12 FBgn0082861 BP1045 BP1045 http://flybase.net/reports/FBgn0082861.html gene unnamed 16-Dec-15 2015_12 FBgn0266219 CR44914 http://flybase.net/reports/FBgn0266219.html non_protein_coding_gene CR44914 16-Dec-15 2015_12 FBgn0035858 CG13674 http://flybase.net/reports/FBgn0035858.html protein_coding_gene CG13674 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC10033 IE -1.903780055 0.736353061 2.187046671 0.734606717 -1.01302419 -0.288072535 FBgn0005023 dpl duplicated legs http://flybase.net/reports/FBgn0005023.html gene dl 16-Dec-15 2015_12 "visible,recessive" "tarsal segment,tibia" FBgn0050272 MFS1 Major Facilitator Superfamily Transporter 1 http://flybase.net/reports/FBgn0050272.html FBgn0034781 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "CG11682, CG30272" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG30272 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" viable FBgn0019846 anon-XX anon-XX http://flybase.net/reports/FBgn0019846.html gene XX 16-Dec-15 2015_12 FBgn0262339 mir-982 mir-982 stem loop http://flybase.net/reports/FBgn0262339.html miRNA_gene "CR43046, dme-mir-982, miR-982" CR43046 16-Dec-15 2015_12 "lethal,visible" "wing,wing margin,wing vein" FBgn0069239 gl(1)145-32 gl(1)145-32 http://flybase.net/reports/FBgn0069239.html gene 0007362=terminal region determination 16-Dec-15 2015_12 "terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryo,germline clone,maternal effect" FBgn0025511 fs(3)82EFe fs(3)82EFe http://flybase.net/reports/FBgn0025511.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0003307 rwi red wine http://flybase.net/reports/FBgn0003307.html gene rw 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0041774 Winnebago Winnebago http://flybase.net/reports/FBgn0041774.html gene 16-Dec-15 2015_12 FBgn0029905 Nf-YC Nuclear factor Y-box C http://flybase.net/reports/FBgn0029905.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0046982=protein heterodimerization activity" "0008589=regulation of smoothened signaling pathway, 0035222=wing disc pattern formation, 0006355=regulation of transcription, DNA-templated, 0007411=axon guidance" "0016602=CCAAT-binding factor complex, 0005634=nucleus" "CG3075, nf-yc, nuclear factor Y-box C, NF-YC-like, NF-YC" "IPR027170=Transcriptional activator NFYC/HAP5 subunit, IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072=Histone-fold" CG3075 16-Dec-15 2015_12 ENSXETG00000025363(nfyc) ENSMUSG00000032897(Nfyc) ENSG00000066136(NFYC) "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,visible" "axon & photoreceptor cell R7 | somatic clone,lamina,axon & photoreceptor cell R7,axon & photoreceptor cell R8,wing,wing vein,supernumerary" FBgn0005309 ms(1)RD15 male sterile (1) RD15 http://flybase.net/reports/FBgn0005309.html gene 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective" "meiotic cell cycle | male,meiotic cell cycle & spindle | male,spermatid & centriole,spermatid,meiosis I" FBgn0034085 Ptp52F Protein tyrosine phosphatase 52F http://flybase.net/reports/FBgn0034085.html protein_coding_gene 0004725=protein tyrosine phosphatase activity "0006470=protein dephosphorylation, 0008045=motor neuron axon guidance, 0007411=axon guidance, 0007399=nervous system development" 0005886=plasma membrane "DPTP52F, ptp52F, CT18044, Ptp52F, PTP52F, CG18243" "IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain, IPR003961=Fibronectin type III, IPR000242=PTP type protein phosphatase, IPR013783=Immunoglobulin-like fold" CG18243 16-Dec-15 2015_12 "neuroanatomy defective,viable" "segmental nerve branch SNa of A1-7,fascicle,central nervous system,longitudinal connective,intersegmental nerve,abdominal segmental nerve,pCC neuron,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,motor neuron" FBgn0045049 fs(1)259 female sterile (1) 259 http://flybase.net/reports/FBgn0045049.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "egg chamber,oocyte,supernumerary" FBgn0065537 l(2)SH1072 lethal (2) SH1072 http://flybase.net/reports/FBgn0065537.html gene l(2)SH2 1072 16-Dec-15 2015_12 "lethal,recessive" FBgn0050432 CG30432 http://flybase.net/reports/FBgn0050432.html protein_coding_gene CG30432 16-Dec-15 2015_12 FBgn0041163 aya aya http://flybase.net/reports/FBgn0041163.html gene 0008586=imaginal disc-derived wing vein morphogenesis 16-Dec-15 2015_12 FBgn0040907 mRpL33 mitochondrial ribosomal protein L33 http://flybase.net/reports/FBgn0040907.html FBgn0063244 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005739=mitochondrion" "BcDNA:GH15938, L33, CG3712" IPR011332=Zinc-binding ribosomal protein CG3712 16-Dec-15 2015_12 ENSMUSG00000029142(Mrpl33) ENSG00000163797 "viable,visible" trichogen cell FBgn0084516 mod(mdg4)::su(Hw) mod(mdg4)::su(Hw) http://flybase.net/reports/FBgn0084516.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0053912 CG33912 http://flybase.net/reports/FBgn0053912.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33912 16-Dec-15 2015_12 FBgn0037741 CG16908 http://flybase.net/reports/FBgn0037741.html protein_coding_gene 0046331=lateral inhibition "IPR016441=TEL2-interacting protein 1, IPR016024=Armadillo-type fold" CG16908 16-Dec-15 2015_12 ENSDARG00000004114(tti1) WBGene00011225(R10H10.7) ENSXETG00000017321(KIAA0406) ENSMUSG00000027650(2610036D13Rik) ENSG00000101407(TTI1) "lethal,viable,visible" "embryonic/larval brain,chaeta,trichogen cell" DRSC15163 K -0.024561478 0.126636288 -0.045799447 0.112178151 1.567168949 1.206019869 FBgn0013646 mfs(3)8 mfs(3)8 http://flybase.net/reports/FBgn0013646.html gene 16-Dec-15 2015_12 "male sterile,female sterile" FBgn0000263 cb club http://flybase.net/reports/FBgn0000263.html gene 16-Dec-15 2015_12 "visible,recessive" "wing,sternopleural bristle" FBgn0041095 scarecrow scarecrow http://flybase.net/reports/FBgn0041095.html gene 16-Dec-15 2015_12 FBgn0031579 CG15422 http://flybase.net/reports/FBgn0031579.html protein_coding_gene CG15422 16-Dec-15 2015_12 viable FBgn0086396 BG02314 http://flybase.net/reports/FBgn0086396.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "viable,smell perception defective" FBgn0036619 Cpr72Ec Cuticular protein 72Ec http://flybase.net/reports/FBgn0036619.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development "0031012=extracellular matrix, 0005615=extracellular space" "CT15377, CG4784" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG4784 16-Dec-15 2015_12 viable FBgn0000542 ec echinus http://flybase.net/reports/FBgn0000542.html FBgn0025376 protein_coding_gene "0008157=protein phosphatase 1 binding, 0004843=ubiquitin-specific protease activity" "0046672=positive regulation of compound eye retinal cell programmed cell death, 0046667=compound eye retinal cell programmed cell death, 0046666=retinal cell programmed cell death, 0006511=ubiquitin-dependent protein catabolic process, 0016318=ommatidial rotation" "Q1W9Q0, EG:EG0002.3, Ec, CG2904" "IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889=Ubiquitin specific protease domain" CG2904 16-Dec-15 2015_12 ENSXETG00000010009(USP54) ENSMUSG00000034235(Usp54) "visible,recessive,decreased cell death,viable,wild-type,short lived,lethal - all die before end of pupal stage,some die during pupal stage" "eye,retina,ommatidium,wing,adult abdomen,adult thorax,dorsocentral bristle,posterior notopleural bristle,primary pigment cell,cone cell,inter-ommatidial precursor cell,supernumerary,primary pigment cell precursor" FBgn0036880 Cpr76Bc Cuticular protein 76Bc http://flybase.net/reports/FBgn0036880.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG9295, DmelCpr76Bc" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG9295 16-Dec-15 2015_12 viable FBgn0052683 CG32683 http://flybase.net/reports/FBgn0052683.html "FBgn0030199, FBgn0030201, FBgn0030203" protein_coding_gene 0007165=signal transduction 0005886=plasma membrane "CG15303, CG2883, CG2881" "IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain, IPR014756=Immunoglobulin E-set, IPR014752=Arrestin, C-terminal, IPR000698=Arrestin, IPR014753=Arrestin, N-terminal" CG32683 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC17990 EK 0.346733423 -0.094888709 1.660604206 0.425483092 1.540212108 1.287898166 FBgn0028901 CG18109 http://flybase.net/reports/FBgn0028901.html FBgn0032572 protein_coding_gene 0007020=microtubule nucleation "0000922=spindle pole, 0005815=microtubule organizing center" "DS02252.3, BG:DS02252.3" "IPR015697=Gamma-tubulin complex component/Spindle pole body component, IPR007259=Gamma-tubulin complex component protein" CG18109 16-Dec-15 2015_12 FBgn0062622 Mod(var)1144 Mod(var)1144 http://flybase.net/reports/FBgn0062622.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1144 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0263207 CR43377 http://flybase.net/reports/FBgn0263207.html pseudogene_attribute CR43377 16-Dec-15 2015_12 FBgn0001902 l(2)22Ac lethal (2) 22Ac http://flybase.net/reports/FBgn0001902.html gene "l(2)neh-16, l(2)neh16" 16-Dec-15 2015_12 lethal FBgn0001193 Hia Hiatus http://flybase.net/reports/FBgn0001193.html gene 16-Dec-15 2015_12 "viable,visible,dominant" wing vein L2 FBgn0032725 Nedd8 Nedd8 http://flybase.net/reports/FBgn0032725.html protein_coding_gene "0048812=neuron projection morphogenesis, 0051438=regulation of ubiquitin-protein transferase activity, 0008283=cell proliferation, 0030431=sleep, 0036099=female germ-line stem cell maintenance, 0008589=regulation of smoothened signaling pathway, 0030162=regulation of proteolysis, 0031647=regulation of protein stability, 0045116=protein neddylation, 0022008=neurogenesis" 0005634=nucleus "neural precursor cell-expressed developmentally downregulated, nedd8, NEDD8, dNEDD8, CG10679" "IPR000626=Ubiquitin domain, IPR019954=Ubiquitin conserved site, IPR029071=Ubiquitin-related domain, IPR019956=Ubiquitin" CG10679 16-Dec-15 2015_12 ENSDARG00000007989(nedd8) WBGene00003587(ned-8) ENSXETG00000027217(nedd8) ENSMUSG00000010376(Nedd8) ENSG00000129559(NEDD8) "lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,female sterile,germline clone,sleep defective" "embryonic/larval salivary gland,adult mushroom body,eye disc,somatic clone,neuron & gamma-lobe,ovary,germline clone,embryonic/larval neuroblast,ganglion mother cell" DRSC02092 E 0.900720889 0.817908229 1.97614075 1.156351074 0.111308176 0.509694476 FBgn0069191 l(3)c00014 lethal (3) c00014 http://flybase.net/reports/FBgn0069191.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0260492 l(3)3456 http://flybase.net/reports/FBgn0260492.html gene 0007409=axonogenesis 16-Dec-15 2015_12 neuroanatomy defective "dendritic arborizing neuron,axon" FBgn0053311 CG33311 http://flybase.net/reports/FBgn0053311.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005727 l(1)TK202 lethal (1) TK202 http://flybase.net/reports/FBgn0005727.html gene l202 16-Dec-15 2015_12 "lethal,recessive" FBgn0036321 CG14120 http://flybase.net/reports/FBgn0036321.html protein_coding_gene "0046872=metal ion binding, 0016787=hydrolase activity, 0003676=nucleic acid binding" "IPR001604=DNA/RNA non-specific endonuclease, IPR020821=Extracellular Endonuclease, subunit A" CG14120 16-Dec-15 2015_12 viable FBgn0267639 CR45977 http://flybase.net/reports/FBgn0267639.html non_protein_coding_gene CR45977 16-Dec-15 2015_12 FBgn0045052 fs(1)234 female sterile (1) 234 http://flybase.net/reports/FBgn0045052.html gene 0048477=oogenesis 16-Dec-15 2015_12 female sterile "germline cell,follicle cell" FBgn0037560 CR18228 http://flybase.net/reports/FBgn0037560.html pseudogene_attribute CG18228 CR18228 16-Dec-15 2015_12 "viable,fertile" FBgn0265549 CR44399 http://flybase.net/reports/FBgn0265549.html non_protein_coding_gene lincRNA.176 CR44399 16-Dec-15 2015_12 FBgn0050016 CG30016 http://flybase.net/reports/FBgn0050016.html FBgn0043525 protein_coding_gene 0033971=hydroxyisourate hydrolase activity 0006144=purine nucleobase metabolic process "unnamed, anon-AE003828.1" "IPR023416=Transthyretin/hydroxyisourate hydrolase, superfamily, IPR000895=Transthyretin/hydroxyisourate hydrolase, IPR014306=Hydroxyisourate hydrolase" CG30016 16-Dec-15 2015_12 ENSDARG00000068644(urah) "WBGene00011181(R09H10.3),WBGene00022808(ZK697.8)" ENSXETG00000019849() ENSMUSG00000025481(1190003J15Rik) ENSG00000118271(TTR) "viable,fertile" FBgn0266116 CR44842 http://flybase.net/reports/FBgn0266116.html non_protein_coding_gene CR44842 16-Dec-15 2015_12 FBgn0031276 CG12506 http://flybase.net/reports/FBgn0031276.html protein_coding_gene cg12506 CG12506 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0052194 CR32194 http://flybase.net/reports/FBgn0052194.html FBgn0047181 non_protein_coding_gene "CG32194, BcDNA:RE06388" CR32194 16-Dec-15 2015_12 FBgn0032217 CG4972 http://flybase.net/reports/FBgn0032217.html protein_coding_gene 0009966=regulation of signal transduction "0012505=endomembrane system, 0016020=membrane" Q9VKZ7_DROME IPR016574=Nicalin CG4972 16-Dec-15 2015_12 "ENSDARG00000058861(LOC100332139),ENSDARG00000012126(zgc:109965)" WBGene00011488(nra-2) ENSXETG00000014348(ncln) ENSMUSG00000020238(Ncln) ENSG00000125912(NCLN) "viable,fertile" FBgn0053137 CG33137 http://flybase.net/reports/FBgn0053137.html FBgn0033801 protein_coding_gene CG4023 "IPR006617=Protein of unknown function DM8, IPR010512=Protein of unknown function DUF1091" CG33137 16-Dec-15 2015_12 FBgn0032408 CG6712 http://flybase.net/reports/FBgn0032408.html protein_coding_gene 0003723=RNA binding 0042254=ribosome biogenesis 0005730=nucleolus ORF2 "IPR004154=Anticodon-binding, IPR007109=Brix domain" CG6712 16-Dec-15 2015_12 ENSDARG00000005738(LOC100334965) YHR088W(RPF1) WBGene00009711(F44G4.1) ENSXETG00000008642(BXDC5) ENSMUSG00000028187(Rpf1) ENSG00000117133(RPF1) " adult stage | female , embryonic stage , embryonic stage | early , adult stage && oogenesis stage | stage S10 " " neuroblast

, embryonic digestive system

, ovary

, organism | ubiquitous

, nurse cell

" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC21690 E 0.792483366 -0.565693137 1.795607302 -0.114702031 -0.782523078 0.358861328 FBgn0266913 CR45373 http://flybase.net/reports/FBgn0266913.html non_protein_coding_gene CR45373 16-Dec-15 2015_12 FBgn0037117 CG11248 http://flybase.net/reports/FBgn0037117.html protein_coding_gene CG11248 16-Dec-15 2015_12 "viable,fertile" FBgn0263040 CG43335 http://flybase.net/reports/FBgn0263040.html FBgn0038351 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH73, CG5302" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG43335 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0019752 l(1)815-22 lethal (1) 815-22 http://flybase.net/reports/FBgn0019752.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010145 l(3)62Bj lethal (3) 62Bj http://flybase.net/reports/FBgn0010145.html gene "l(3)dre7, dre7" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0000624 Eye Eyeless dominant on 2 http://flybase.net/reports/FBgn0000624.html gene "ey-II[D], Eyeless dominant in chromosome 2" 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "eye,antenna" FBgn0036403 CG6661 http://flybase.net/reports/FBgn0036403.html protein_coding_gene "0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, 0003842=1-pyrroline-5-carboxylate dehydrogenase activity" "0055114=oxidation-reduction process, 0006560=proline metabolic process" 0005759=mitochondrial matrix "PUT2, CR33944" "IPR015590=Aldehyde dehydrogenase domain, IPR016161=Aldehyde/histidinol dehydrogenase, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR016163=Aldehyde dehydrogenase, C-terminal" CG6661 16-Dec-15 2015_12 viable FBgn0051216 Naam Nicotinamide amidase http://flybase.net/reports/FBgn0051216.html "FBgn0038728, FBgn0038729, FBgn0046372, FBgn0046373" protein_coding_gene "0005509=calcium ion binding, 0008936=nicotinamidase activity" "0006979=response to oxidative stress, 0008152=metabolic process, 0008340=determination of adult lifespan, 0043524=negative regulation of neuron apoptotic process" "anon-WO0172774.59, nicotinamide amidase, CG31216, Nicotinamidase, anon-WO0172774.60, D-NAAM, CG7500, AAM52663, CG7444" "IPR000868=Isochorismatase-like, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG31216 16-Dec-15 2015_12 YGL037C(PNC1) "WBGene00021395(pnc-1),WBGene00013336(pnc-2)" "long lived,viable,auditory perception defective" FBgn0053318 CR33318 http://flybase.net/reports/FBgn0053318.html FBgn0032905 pseudogene_attribute CG18078 CR33318 16-Dec-15 2015_12 FBgn0260038 33AA12 http://flybase.net/reports/FBgn0260038.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0267994 CR46261 http://flybase.net/reports/FBgn0267994.html non_protein_coding_gene CR46261 16-Dec-15 2015_12 FBgn0040296 Ocho Ocho http://flybase.net/reports/FBgn0040296.html "FBgn0036457, FBgn0036458" protein_coding_gene 0005515=protein binding "0007219=Notch signaling pathway, 0007423=sensory organ development" "ocho, DmelCG3396, CG5138, CG3396" IPR029686=Enhancer of split malpha/m4 CG3396 16-Dec-15 2015_12 viable FBgn0020867 auk auk http://flybase.net/reports/FBgn0020867.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces "gon, gonfle" 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone" FBgn0003503 srd small round http://flybase.net/reports/FBgn0003503.html gene 16-Dec-15 2015_12 "viable,fertile,visible,eye color defective" "eye,pigment cell,postvertical bristle" FBgn0027127 l(3)H94 lethal (3) H94 http://flybase.net/reports/FBgn0027127.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0004074 ovt ovarian tumor http://flybase.net/reports/FBgn0004074.html gene 16-Dec-15 2015_12 "female sterile,recessive" FBgn0264736 ato::Bmor\ato http://flybase.net/reports/FBgn0264736.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0264526 ff27 http://flybase.net/reports/FBgn0264526.html gene 16-Dec-15 2015_12 "meiotic cell cycle defective,male" spermatid FBgn0038732 CG11391 http://flybase.net/reports/FBgn0038732.html protein_coding_gene "0003824=catalytic activity, 0005324=long-chain fatty acid transporter activity" 0008152=metabolic process "IPR020845=AMP-binding, conserved site, IPR000873=AMP-dependent synthetase/ligase, IPR025110=AMP-binding enzyme C-terminal domain" CG11391 16-Dec-15 2015_12 "viable,fertile" FBgn0060452 l(3)S119607b lethal (3) S119607b http://flybase.net/reports/FBgn0060452.html gene 1196/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0264913 CG44104 http://flybase.net/reports/FBgn0264913.html protein_coding_gene 16-Dec-15 2015_12 FBgn0033422 Or45b Odorant receptor 45b http://flybase.net/reports/FBgn0033422.html protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0016021=integral component of membrane" "45F.1, DOR107, CG12931, 45b" "IPR004117=Olfactory receptor, Drosophila" CG12931 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0033358 CG8216 http://flybase.net/reports/FBgn0033358.html protein_coding_gene Apis-ITG-like CG8216 16-Dec-15 2015_12 viable FBgn0001037 fs(3)G5 female sterile (3) G5 http://flybase.net/reports/FBgn0001037.html gene fs(3)5 16-Dec-15 2015_12 "female sterile,male fertile" "ovariole,egg chamber" FBgn0035517 CG1265 http://flybase.net/reports/FBgn0035517.html FBgn0063067 protein_coding_gene BcDNA:RE09466 "IPR016817=Mannose-P-dolichol utilization defect 1 protein, IPR006603=PQ-loop repeat" CG1265 16-Dec-15 2015_12 ENSDARG00000054251(pqlc3) ENSMUSG00000045679(Pqlc3) ENSG00000162976(PQLC3) viable embryonic/larval hemocyte | third instar larval stage FBgn0069991 BG01950 BG01950 http://flybase.net/reports/FBgn0069991.html gene 16-Dec-15 2015_12 "stress response defective,long lived,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0001742 l(1)HM12 lethal (1) HM12 http://flybase.net/reports/FBgn0001742.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0039897 CG1674 http://flybase.net/reports/FBgn0039897.html protein_coding_gene 0030018=Z disc CG1674 16-Dec-15 2015_12 viable FBgn0016831 l(1)MZ18 lethal (1) MZ18 http://flybase.net/reports/FBgn0016831.html gene M18 16-Dec-15 2015_12 "lethal,recessive" FBgn0029708 CG3556 http://flybase.net/reports/FBgn0029708.html protein_coding_gene 0031419=cobalamin binding 0015889=cobalamin transport "IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR002157=Cobalamin (vitamin B12)-binding transporter, eukaryotic, IPR019554=Soluble ligand binding domain" CG3556 16-Dec-15 2015_12 "viable,fertile" FBgn0015951 jnh jekyll and hyde http://flybase.net/reports/FBgn0015951.html gene 16-Dec-15 2015_12 FBgn0261999 CG42817 http://flybase.net/reports/FBgn0261999.html "FBgn0028859, FBan0012455, FBgn0032581, FBgn0044794" protein_coding_gene "BG:DS07473.1, DS07473.1A, CG12455" "IPR002035=von Willebrand factor, type A, IPR004010=Cache domain, IPR013608=VWA N-terminal" CG42817 16-Dec-15 2015_12 "viable,fertile" FBgn0085667 CG41522 http://flybase.net/reports/FBgn0085667.html FBan0041522 protein_coding_gene 16-Dec-15 2015_12 FBgn0266839 CR45301 http://flybase.net/reports/FBgn0266839.html non_protein_coding_gene CR45301 16-Dec-15 2015_12 FBgn0031080 CG12655 http://flybase.net/reports/FBgn0031080.html protein_coding_gene CG12655 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC20678 K -0.322108592 0.608937546 0.392324931 0.316238674 -2.160465362 -0.060984946 FBgn0003702 tht thickset http://flybase.net/reports/FBgn0003702.html gene 16-Dec-15 2015_12 "male fertile,viable,male,poor,visible" "eye,ommatidium" FBgn0029087 enPRE engrailed Polycomb group response element http://flybase.net/reports/FBgn0029087.html regulatory_region en PRE 16-Dec-15 2015_12 FBgn0001035 fs(3)G2 female sterile (3) G2 http://flybase.net/reports/FBgn0001035.html gene fs(3)2 16-Dec-15 2015_12 "female sterile,male sterile,partially,viable,poor,male semi-sterile" "egg chamber,oocyte" FBgn0031043 NAA20 N(alpha)-acetyltransferase 20 http://flybase.net/reports/FBgn0031043.html protein_coding_gene "0019186=acyl-CoA N-acyltransferase activity, 0004402=histone acetyltransferase activity" "NAA20 ortholog, DmAAF48987, dNAA20, CG14222" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG14222 16-Dec-15 2015_12 ENSDARG00000039493 YPR131C(NAT3) WBGene00022394(Y97E10AL.3) ENSMUSG00000002728(Naa20) ENSG00000173418(NAA20) "viable,visible" mesothoracic tergum FBgn0062656 EP339 EP339 http://flybase.net/reports/FBgn0062656.html gene EP(3)0339 16-Dec-15 2015_12 FBgn0036600 CG13043 http://flybase.net/reports/FBgn0036600.html FBgn0047040 protein_coding_gene "CT32262, BcDNA:RH10371" IPR007614=Retinin-like protein CG13043 16-Dec-15 2015_12 "viable,fertile" FBgn0085669 CG41526 http://flybase.net/reports/FBgn0085669.html FBan0041526 protein_coding_gene 16-Dec-15 2015_12 FBgn0032750 CG10495 http://flybase.net/reports/FBgn0032750.html FBgn0062174 protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0017150=tRNA dihydrouridine synthase activity" "0055114=oxidation-reduction process, 0008033=tRNA processing" anon-WO0118547.200 "IPR001269=tRNA-dihydrouridine synthase, IPR013785=Aldolase-type TIM barrel, IPR018517=tRNA-dihydrouridine synthase, conserved site" CG10495 16-Dec-15 2015_12 ENSDARG00000006567(zgc:92033) YLR405W(DUS4) WBGene00016674(C45G9.2) ENSXETG00000005925(dus4l) ENSMUSG00000020648(Dus4l) ENSG00000105865(DUS4L) FBgn0032520 CG10859 http://flybase.net/reports/FBgn0032520.html protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled" 0007018=microtubule-based movement "0005868=cytoplasmic dynein complex, 0005875=microtubule associated complex, 0030286=dynein complex" unnamed "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG10859 16-Dec-15 2015_12 WBGene00016165(C27F2.1) viable FBgn0005010 Din Dinty http://flybase.net/reports/FBgn0005010.html gene 16-Dec-15 2015_12 "visible,dominant,viable,fertile" "wing vein L2,supraalar bristle,anterior postalar bristle,wing" FBgn0265751 CR44558 http://flybase.net/reports/FBgn0265751.html non_protein_coding_gene lincRNA.543 CR44558 16-Dec-15 2015_12 FBgn0033667 reb rebuf http://flybase.net/reports/FBgn0033667.html protein_coding_gene "0006031=chitin biosynthetic process, 0060439=trachea morphogenesis, 0006035=cuticle chitin biosynthetic process, 0006355=regulation of transcription, DNA-templated" "0045177=apical part of cell, 0005737=cytoplasm" CG13183 "IPR008984=SMAD/FHA domain, IPR001132=SMAD domain, Dwarfin-type, IPR017855=SMAD domain-like" CG13183 16-Dec-15 2015_12 viable FBgn0265340 CR44294 http://flybase.net/reports/FBgn0265340.html non_protein_coding_gene CR44294 16-Dec-15 2015_12 FBgn0050088 CG30088 http://flybase.net/reports/FBgn0050088.html FBgn0034038 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP41, CG8215" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG30088 16-Dec-15 2015_12 WBGene00006621(try-3) viable DRSC24797 K -0.160133368 -0.036267953 -0.530845363 -0.751119297 -3.224469765 0.838176669 FBgn0265689 CR44496 http://flybase.net/reports/FBgn0265689.html non_protein_coding_gene CR44496 16-Dec-15 2015_12 FBgn0267989 CR46256 http://flybase.net/reports/FBgn0267989.html non_protein_coding_gene CR46256 16-Dec-15 2015_12 FBgn0036260 Rh7 Rhodopsin 7 http://flybase.net/reports/FBgn0036260.html "FBgn0046540, FBgn0046541" protein_coding_gene 0008020=G-protein coupled photoreceptor activity "0007601=visual perception, 0007186=G-protein coupled receptor signaling pathway" 0016021=integral component of membrane "CG5638, anon-WO0170980.34, DMELRH7, Rhodopsin, anon-WO0170980.35, rh7, Rh, rhodopsin" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR027430=Visual pigments (opsins) retinal binding site, IPR017452=GPCR, rhodopsin-like, 7TM, IPR001760=Opsin" CG5638 16-Dec-15 2015_12 viable FBgn0022144 l(2)k06107 lethal (2) k06107 http://flybase.net/reports/FBgn0022144.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0040785 CG12554 http://flybase.net/reports/FBgn0040785.html protein_coding_gene 16-Dec-15 2015_12 FBgn0267223 CR45663 http://flybase.net/reports/FBgn0267223.html non_protein_coding_gene CR45663 16-Dec-15 2015_12 FBgn0044077 E(rst)H94 E(rst)H94 http://flybase.net/reports/FBgn0044077.html gene 0001745=compound eye morphogenesis H94 16-Dec-15 2015_12 viable FBgn0000686 l(1)adl16 lethal (1) adl16 http://flybase.net/reports/FBgn0000686.html FBgn0010122 gene "flight reduced I, l(1)adl-16, l(1)DC359, flrdI, l(1)DC836" 16-Dec-15 2015_12 "lethal,heat sensitive,visible,short lived" "proboscis,heat sensitive,adult abdomen" FBgn0041168 anon-A3 anon-A3 http://flybase.net/reports/FBgn0041168.html gene A3 16-Dec-15 2015_12 FBgn0024610 olf702 olfactory 702 http://flybase.net/reports/FBgn0024610.html gene 16-Dec-15 2015_12 FBgn0015829 TfIIEë_ Transcription factor IIEë_ http://flybase.net/reports/FBgn0015829.html protein_coding_gene "0022008=neurogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0005634=nucleus, 0005673=transcription factor TFIIE complex" "dTFIIES, TFIIbeta, CG1276, TFIIE, TfIIE, TFIIEbeta, TfIIEbeta, TFIIE small subunit, dTFIIE-S, E[[S]]" "IPR016656=Transcription initiation factor TFIIE, beta subunit, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR003166=Transcription factor TFIIE beta subunit, DNA-binding domain" CG1276 16-Dec-15 2015_12 ENSDARG00000012672(gtf2e2) YKR062W(TFA2) WBGene00010054(F54D5.11) ENSXETG00000011291(gtf2e2) ENSMUSG00000031585(Gtf2e2) ENSG00000197265(GTF2E2) "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0023524 CG3078 http://flybase.net/reports/FBgn0023524.html protein_coding_gene EG:30B8.6 IPR020846=Major facilitator superfamily domain CG3078 16-Dec-15 2015_12 DRSC18531 E -0.041557708 -0.845271116 -2.186401317 -0.522114799 -0.829104816 -0.612514432 FBgn0044010 Su(rst)B16 Su(rst)B16 http://flybase.net/reports/FBgn0044010.html gene 0001745=compound eye morphogenesis B16 16-Dec-15 2015_12 viable eye FBgn0034456 Ir56b Ionotropic receptor 56b http://flybase.net/reports/FBgn0034456.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 56b, CG15121, DmelIR56b, IR56b" CG15121 16-Dec-15 2015_12 viable DRSC06543 K 0.787165879 0.054280992 0.40471128 0.024213006 -0.778892273 -2.013111928 FBgn0263652 CR43643 http://flybase.net/reports/FBgn0263652.html non_protein_coding_gene CR43643 16-Dec-15 2015_12 FBgn0266704 CR45194 http://flybase.net/reports/FBgn0266704.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0036169 Fuca ë±-L-fucosidase http://flybase.net/reports/FBgn0036169.html "FBgn0053047, FBtr0076156, FBpp0075887, FBtr0076157, FBpp0075888, FBtr0076158, FBpp0075889" protein_coding_gene "0042806=fucose binding, 0004560=alpha-L-fucosidase activity" "0006004=fucose metabolic process, 0042742=defense response to bacterium, 0016139=glycoside catabolic process" "Fuca_Dm, CG6128, DmFuca, alpha-L-fucosidase, CG33047" "IPR013781=Glycoside hydrolase, catalytic domain, IPR016286=Alpha-L-fucosidase, metazoa-type, IPR017853=Glycoside hydrolase superfamily, IPR000933=Glycoside hydrolase, family 29" CG6128 16-Dec-15 2015_12 "ENSDARG00000044073(fuca2),ENSDARG00000035890(fuca1),ENSDARG00000035879(zgc:101116)" WBGene00012225(W03G11.3) ENSXETG00000009786(fuca2) "ENSMUSG00000019810(Fuca2),ENSMUSG00000028673(Fuca1)" "ENSG00000001036(FUCA2),ENSG00000179163(FUCA1)" "viable,fertile" FBgn0015366 bnd-35 bnd-35 http://flybase.net/reports/FBgn0015366.html gene 16-Dec-15 2015_12 FBgn0014454 Acp1 Adult cuticle protein 1 http://flybase.net/reports/FBgn0014454.html protein_coding_gene 0008012=structural constituent of adult chitin-based cuticle "acp1, CG7216, CG7216-PA, Adult Cuticle Protein 1, Dacp-1" CG7216 16-Dec-15 2015_12 adult stage " epidermis &&of adult head

, epidermis &&of adult thorax

" FBgn0022742 anon-UJB6 anon-UJB6 http://flybase.net/reports/FBgn0022742.html gene 16-Dec-15 2015_12 FBgn0031318 CG4887 http://flybase.net/reports/FBgn0031318.html protein_coding_gene "0008270=zinc ion binding, 0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome cg4887 "IPR001876=Zinc finger, RanBP2-type, IPR000504=RNA recognition motif domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR000467=G-patch domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG4887 16-Dec-15 2015_12 YNL224C(SQS1) WBGene00020346(T08B2.5) ENSXETG00000007303(RBM5) "ENSMUSG00000032580(Rbm5),ENSMUSG00000031060(Rbm10)" "ENSG00000003756(RBM5),ENSG00000182872(RBM10)" "viable,visible" trichogen cell FBgn0024694 en::ftz::Mmus\En1 En1 http://flybase.net/reports/FBgn0024694.html engineered_fusion_gene en::ftz::Mus\En1 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" denticle belt FBgn0004194 snRNA:U2:84Cb small nuclear RNA U2 at 84Cb http://flybase.net/reports/FBgn0004194.html "FBgn0003919, FBgn0003924" snRNA_gene "0000398=mRNA splicing, via spliceosome" 0015030=Cajal body "U2 snRNA, U2snRNA, U2, small nuclear RNA U2, snRNA:U2, dU2, U2snRNA84Cb" 16-Dec-15 2015_12 FBgn0265515 su(comt6)S14 suppressor of comatose6 S14 http://flybase.net/reports/FBgn0265515.html gene 16-Dec-15 2015_12 FBgn0067773 fragile-locus-C fragile locus C http://flybase.net/reports/FBgn0067773.html gene 0007343=egg activation 16-Dec-15 2015_12 "lethal,maternal effect" FBgn0260035 32C40 http://flybase.net/reports/FBgn0260035.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0035430 CG12009 http://flybase.net/reports/FBgn0035430.html protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG12009 16-Dec-15 2015_12 viable FBgn0262902 CR43257 http://flybase.net/reports/FBgn0262902.html non_protein_coding_gene CR43257 16-Dec-15 2015_12 FBgn0014466 Cp7Fc Chorion protein c at 7F http://flybase.net/reports/FBgn0014466.html FBgn0030045 protein_coding_gene 0007304=chorion-containing eggshell formation 0042600=chorion "s37, CG15351, E, D" CG15351 16-Dec-15 2015_12 " oogenesis stage | stage S11-12 , adult stage | female && oogenesis stage | stage S10-13 , adult stage && oogenesis stage | stage S10B-13 " "

, organism

, follicle cell

" viable FBgn0031903 Wnt10 Wnt oncogene analog 10 http://flybase.net/reports/FBgn0031903.html protein_coding_gene "0005102=receptor binding, 0001664=G-protein coupled receptor binding" "0042067=establishment of ommatidial planar polarity, 0001737=establishment of imaginal disc-derived wing hair orientation, 0009798=axis specification, 0007435=salivary gland morphogenesis, 0060070=canonical Wnt signaling pathway, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0008585=female gonad development, 0009952=anterior/posterior pattern specification, 0016055=Wnt signaling pathway" "0005615=extracellular space, 0005886=plasma membrane, 0005576=extracellular region" "wnt10, Wnt10, DWnt-10, CG4971, D-Wnt-10, Dm DWnt10, DWnt10" "IPR005817=Wnt, IPR018161=Wnt protein, conserved site" CG4971 16-Dec-15 2015_12 "ENSDARG00000017155(wnt10a),ENSDARG00000040925(wnt10b)" "ENSMUSG00000026167(Wnt10a),ENSMUSG00000022996(Wnt10b)" "ENSG00000135925(WNT10A),ENSG00000169884(WNT10B)" FBgn0003296 rub rubroad http://flybase.net/reports/FBgn0003296.html gene 16-Dec-15 2015_12 "visible,recessive" "eye,wing,abdomen,male genitalia,tergite,wing vein" FBgn0033716 Den1 Deneddylase 1 http://flybase.net/reports/FBgn0033716.html protein_coding_gene 0019784=NEDD8-specific protease activity "0000338=protein deneddylation, 0043065=positive regulation of apoptotic process" "DEN1, deneddylase 1, CG8493" "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG8493 16-Dec-15 2015_12 ENSDARG00000019595(zgc:153043) WBGene00006738(ulp-3) "ENSXETG00000005208(),ENSXETG00000014299()" ENSMUSG00000051705(Senp8) ENSG00000166192(SENP8) "viable,fertile" FBgn0032161 CG4594 http://flybase.net/reports/FBgn0032161.html protein_coding_gene 0004165=dodecenoyl-CoA delta-isomerase activity 0008152=metabolic process 0005739=mitochondrion "IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily" CG4594 16-Dec-15 2015_12 ENSDARG00000018002 ENSXETG00000017302(dci) ENSMUSG00000024132(Dci) ENSG00000167969(ECI1) "viable,fertile" FBgn0005005 Dented Dented http://flybase.net/reports/FBgn0005005.html gene De 16-Dec-15 2015_12 "visible,semidominant,viable,fertile" "adult thorax,wing" FBgn0260428 CG42523 http://flybase.net/reports/FBgn0260428.html protein_coding_gene CG42523 16-Dec-15 2015_12 FBgn0024543 l(3)L3051 lethal (3) L3051 http://flybase.net/reports/FBgn0024543.html gene Mgn095159 16-Dec-15 2015_12 "lethal,recessive" FBgn0028349 l(1)G0175 lethal (1) G0175 http://flybase.net/reports/FBgn0028349.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "chaeta,wing" FBgn0039297 CG11852 http://flybase.net/reports/FBgn0039297.html protein_coding_gene 0005615=extracellular space CT33073 IPR010562=Haemolymph juvenile hormone binding CG11852 16-Dec-15 2015_12 viable FBgn0030589 CG9519 http://flybase.net/reports/FBgn0030589.html protein_coding_gene "0008812=choline dehydrogenase activity, 0016491=oxidoreductase activity, 0050660=flavin adenine dinucleotide binding" "0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process" Dm GMCtheta1 "IPR012132=Glucose-methanol-choline oxidoreductase, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG9519 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) viable FBgn0265705 CR44512 http://flybase.net/reports/FBgn0265705.html non_protein_coding_gene CR44512 16-Dec-15 2015_12 FBgn0003095 pl pleated http://flybase.net/reports/FBgn0003095.html gene 16-Dec-15 2015_12 visible "wing,cold sensitive" FBgn0031879 uif uninflatable http://flybase.net/reports/FBgn0031879.html protein_coding_gene "0005112=Notch binding, 0005509=calcium ion binding" "0045746=negative regulation of Notch signaling pathway, 0035152=regulation of tube architecture, open tracheal system, 0046716=muscle cell cellular homeostasis" 0016324=apical plasma membrane "SP1070, CG9138, Poly-EGF, poly-EGF, CT26172, Uif, sp1070, uif, uninflatable, Uninflatable" "IPR003410=HYR domain, IPR016187=C-type lectin fold, IPR000421=Coagulation factor 5/8 C-terminal domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001368=TNFR/NGFR cysteine-rich region, IPR016186=C-type lectin-like, IPR001881=EGF-like calcium-binding domain, IPR000859=CUB domain, IPR000436=Sushi/SCR/CCP domain, IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR001304=C-type lectin, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR008979=Galactose-binding domain-like, IPR011641=Tyrosine-protein kinase ephrin type A/B receptor-like, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG9138 16-Dec-15 2015_12 WBGene00018546(F47C12.1) ENSMUSG00000028369(Svep1) ENSG00000165124(SVEP1) "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,small body,feeding behavior defective,partially lethal - majority die,visible" "embryonic/larval tracheal system,embryo,cephalopharyngeal skeleton,embryonic/larval dorsal trunk,taenidium,chaeta,supernumerary,trichogen cell,mesothoracic tergum,wing margin,wing vein,notal microchaeta,eye" FBgn0266001 CR44775 http://flybase.net/reports/FBgn0266001.html non_protein_coding_gene CR44775 16-Dec-15 2015_12 FBgn0040979 CG15285 http://flybase.net/reports/FBgn0040979.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083246 EB4 EB4 http://flybase.net/reports/FBgn0083246.html gene 16-Dec-15 2015_12 FBgn0266682 CR45172 http://flybase.net/reports/FBgn0266682.html non_protein_coding_gene CR45172 16-Dec-15 2015_12 FBgn0052823 Sdic3 Sperm-specific dynein intermediate chain 3 http://flybase.net/reports/FBgn0052823.html protein_coding_gene 0003777=microtubule motor activity 0007018=microtubule-based movement "0036126=sperm flagellum, 0005858=axonemal dynein complex" "Sdic:CG32823, CG32823" "IPR025956=Cytoplasmic dynein 1 intermediate chain 1/2, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG32823 16-Dec-15 2015_12 "ENSDARG00000005756(dync1i2a),ENSDARG00000022487,ENSDARG00000060948(zgc:158394),ENSDARG00000063383(dync1i2b)" YDR488C(PAC11) WBGene00015927(dyci-1) "ENSXETG00000020285(dnci2),ENSXETG00000020277(DYNC1I1)" "ENSMUSG00000027012(Dync1i2),ENSMUSG00000029757(Dync1i1)" "ENSG00000077380(DYNC1I2),ENSG00000158560(DYNC1I1)" FBgn0069923 CG41128 http://flybase.net/reports/FBgn0069923.html "FBgn0047001, FBan0041128" protein_coding_gene 0005739=mitochondrion "RH61753p, Minos1b, BcDNA:RH61753, Mitochondrial INner membrane Organizing System 1" IPR007512=Protein of unknown function DUF543 CG41128 16-Dec-15 2015_12 ENSDARG00000070217(zgc:153623) WBGene00018784(F54A3.5) ENSMUSG00000050608(2310028O11Rik) ENSG00000173436(C1orf151) FBgn0259755 ms(2)Fra-38 http://flybase.net/reports/FBgn0259755.html gene "0007283=spermatogenesis, 0051276=chromosome organization" 16-Dec-15 2015_12 male sterile "Y chromosome loop,Nebenkern,spermatozoon" FBgn0037358 elm ethanol sensitive with low memory http://flybase.net/reports/FBgn0037358.html protein_coding_gene 0005509=calcium ion binding 0005886=plasma membrane "CG2185, elm, ethanol sensitive with low memory" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG2185 16-Dec-15 2015_12 ENSDARG00000052859(zgc:63904) "WBGene00014109(ZK856.8),WBGene00019108(F59D6.7)" ENSXETG00000017901(chp) "ENSMUSG00000014077(1500003O03Rik),ENSMUSG00000030865(2010110P09Rik)" "ENSG00000187446(CHP),ENSG00000166869(CHP2)" "chemical sensitive,memory defective,viable,fertile" FBgn0024532 l(3)L0580 lethal (3) L0580 http://flybase.net/reports/FBgn0024532.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0033570 ND-B14 NADH dehydrogenase (ubiquinone) B14 subunit http://flybase.net/reports/FBgn0033570.html FBgn0047142 protein_coding_gene "0003954=NADH dehydrogenase activity, 0008137=NADH dehydrogenase (ubiquinone) activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "BcDNA:RE25411, NB4M, NADH:ubiquinone oxidoreductase B14 subunit, FBpp0087333, CG7712, NADH ubiquinone oxidoreductase B14, NADH-ubiquinone oxidoreductase B14 subunit" "IPR016488=NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6, IPR008011=Complex 1 LYR protein" CG7712 16-Dec-15 2015_12 ENSDARG00000038028(ndufa6) WBGene00013308(nuo-3) ENSXETG00000000256(NDUFA6) ENSMUSG00000022450(Ndufa6) ENSG00000184983(NDUFA6) FBgn0259305 EP-731 http://flybase.net/reports/FBgn0259305.html gene 16-Dec-15 2015_12 visible wing FBgn0278600 CG46270 http://flybase.net/reports/FBgn0278600.html protein_coding_gene CG46270 16-Dec-15 2015_12 FBgn0039909 ND-49 NADH dehydrogenase (ubiquinone) 49 kDa subunit http://flybase.net/reports/FBgn0039909.html protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0051287=NAD binding, 0003954=NADH dehydrogenase activity, 0048038=quinone binding" "0046331=lateral inhibition, 0006120=mitochondrial electron transport, NADH to ubiquinone, 0048812=neuron projection morphogenesis" "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "NADH:ubiquinone oxidoreductase 49 kDa subunit, NUCM, CG 1970, CG1970, NADH-ubiquinone oxidoreductase 49 kDa subunit, NADH ubiquinone oxidoreductase 49 kDa, FBpp0088174" "IPR029014=NiFe hydrogenase-like, IPR014029=NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site, IPR022885=NAD(P)H-quinone oxidoreductase subunit D/H, IPR001135=NADH-quinone oxidoreductase, subunit D" CG1970 16-Dec-15 2015_12 ENSDARG00000007526(ndufs2) "WBGene00001520(gas-1),WBGene00006463(nduf-2.2)" ENSXETG00000025925(ndufs2) ENSMUSG00000013593(Ndufs2) ENSG00000158864(NDUFS2) "viable,visible" "chaeta,trichogen cell,adult heart,RU486 conditional" FBgn0267058 CR45502 http://flybase.net/reports/FBgn0267058.html non_protein_coding_gene CR45502 16-Dec-15 2015_12 FBgn0060868 l(3)S047212b lethal (3) S047212b http://flybase.net/reports/FBgn0060868.html gene 0472/12 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0036466 CG18581 http://flybase.net/reports/FBgn0036466.html protein_coding_gene CG18581 16-Dec-15 2015_12 viable FBgn0014069 Su(tor)3-8 Su(tor)3-8 http://flybase.net/reports/FBgn0014069.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0031040 CG14210 http://flybase.net/reports/FBgn0031040.html FBgn0047147 protein_coding_gene 0022008=neurogenesis BcDNA:RE23450 IPR005579=Cgr1-like CG14210 16-Dec-15 2015_12 WBGene00012739(Y40B1B.7) "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC19566 I -1.335384013 -1.846094513 0.148512678 -0.75149321 -0.006131984 -0.705589035 FBgn0037317 CG14667 http://flybase.net/reports/FBgn0037317.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR022755=Zinc finger, double-stranded RNA binding, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like" CG14667 16-Dec-15 2015_12 viable FBgn0028073 l(3)S089004 l(3)S089004 http://flybase.net/reports/FBgn0028073.html FBgn0028072 gene "l(3)S089302, 0893/02, 0890/04" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte nucleus,nurse cell & nucleusS089004S089004),follicle cell,nurse cell & nucleusS089004S089302)" FBgn0040210 iab-2PRE iab-2 Polycomb group response element http://flybase.net/reports/FBgn0040210.html regulatory_region 16-Dec-15 2015_12 FBgn0032924 Nbr Nibbler http://flybase.net/reports/FBgn0032924.html protein_coding_gene "0003676=nucleic acid binding, 0044748=3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing" 0044747=mature miRNA 3'-end processing 0030529=ribonucleoprotein complex "CG9247, nibbler, nbr" "IPR002562=3'-5' exonuclease domain, IPR012337=Ribonuclease H-like domain" CG9247 16-Dec-15 2015_12 "WBGene00014220(ZK1098.3),WBGene00003504(mut-7)" ENSXETG00000003957(EXD3) ENSG00000187609(EXD3) "viable,fertile,partially lethal - majority die,sterile,lethal,some die during pupal stage" FBgn0000831 fs(1)M13 female sterile (1) M13 http://flybase.net/reports/FBgn0000831.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,female sterile,lethal,some die during embryonic stage" "egg,maternal effect,chorion | maternal effect,chorion" FBgn0038159 CG14369 http://flybase.net/reports/FBgn0038159.html protein_coding_gene CG14369 16-Dec-15 2015_12 viable FBgn0004494 Ether-resistant Ether-resistant http://flybase.net/reports/FBgn0004494.html gene Eth 16-Dec-15 2015_12 "radiation sensitive,chemical resistant,dominant" FBgn0033473 CG12128 http://flybase.net/reports/FBgn0033473.html protein_coding_gene "IPR012340=Nucleic acid-binding, OB-fold, IPR003750=Putative RNA methyltransferase, IPR029026=tRNA (guanine-N1-)-methyltransferase, N-terminal, IPR029028=Alpha/beta knot methyltransferases" CG12128 16-Dec-15 2015_12 ENSDARG00000019707(zgc:101748) "YMR310C(),YGR283C()" WBGene00015160(B0361.6) ENSXETG00000004745(TNeu130l24.1) ENSMUSG00000039660(D2Wsu81e) ENSG00000198917(C9orf114) viable FBgn0029019 l(3)77CDe lethal (3) 77CDe http://flybase.net/reports/FBgn0029019.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0020621 Pkn Protein kinase N http://flybase.net/reports/FBgn0020621.html "FBgn0004459, FBgn0010625, FBgn0015480, FBgn0028556, FBgn0033398, FBgn0033399" protein_coding_gene "0004697=protein kinase C activity, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding, 0005515=protein binding" "0046777=protein autophosphorylation, 0006468=protein phosphorylation, 0031532=actin cytoskeleton reorganization, 0090303=positive regulation of wound healing, 0007391=dorsal closure, 0007472=wing disc morphogenesis, 0007165=signal transduction" "0005737=cytoplasm, 0005829=cytosol" "CG2055, CT6637, Protein kinase N, CG2049, Dpkn, l(2)06736, protein kinase c related, PRK2, Pk?3, pkn, 3-2, Protein kinase related to protein kinase N, Protein kinase-like 45C, dPKN, CT6660, protein kinase N, l(2)45Ca, Pk45C, v(2)rG232, DPKN, PKC-related, PKN" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR008271=Serine/threonine-protein kinase, active site, IPR000008=C2 domain, IPR011009=Protein kinase-like domain, IPR017892=Protein kinase, C-terminal, IPR000719=Protein kinase domain, IPR011072=HR1 rho-binding repeat" CG2049 16-Dec-15 2015_12 "ENSDARG00000006705(LOC571965),ENSDARG00000060184(LOC560840)" WBGene00016980(C56G2.5) ENSXETG00000020605(PKN1) "ENSMUSG00000057672(Pkn1),ENSMUSG00000004591(Pkn2)" "ENSG00000123143(PKN1),ENSG00000065243(PKN2)" "wound healing defective,viable,lethal,polyphasic,recessive,visible,partially lethal - majority die,male sterile,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,fertile" "dorsal closure embryo,germline clone,embryonic epidermis,dorsal,wing,wing margin bristle,wing vein,ectopic,wing hair,supernumerary,anterior wing margin,posterior wing margin,ommatidium" DRSC06809 I 0.666745006 -1.745623325 -0.118369712 -0.884659075 -0.673451338 -0.225938992 FBgn0060583 l(3)S094503 lethal (3) S094503 http://flybase.net/reports/FBgn0060583.html gene 0945/03 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0032382 Mal-B2 Maltase B2 http://flybase.net/reports/FBgn0032382.html protein_coding_gene "0043169=cation binding, 0004558=alpha-1,4-glucosidase activity" 0005975=carbohydrate metabolic process "mal_B2, Drome_B2, CG14935, FBgn0032382" "IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR017853=Glycoside hydrolase superfamily, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR015902=Glycoside hydrolase, family 13" CG14935 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable FBgn0262243 mir-964 mir-964 stem loop http://flybase.net/reports/FBgn0262243.html miRNA_gene "0006955=immune response, 0060259=regulation of feeding behavior" "miR964, 964, dme-miR-964-5p, dme-mir-964, miR-964, CR42950" CR42950 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein" FBgn0044494 DTD45.7 DTD45.7 http://flybase.net/reports/FBgn0044494.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260377 GSd230 http://flybase.net/reports/FBgn0260377.html gene 16-Dec-15 2015_12 lethal FBgn0069302 X-97-26 X-97-26 http://flybase.net/reports/FBgn0069302.html gene 0007367=segment polarity determination 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,terminal phenotype,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0066099 MCP-3.s MCP-3.s http://flybase.net/reports/FBgn0066099.html gene MCP-3 s 16-Dec-15 2015_12 FBgn0029778 RhoGAP5A Rho GTPase activating protein at 5A http://flybase.net/reports/FBgn0029778.html protein_coding_gene "0019992=diacylglycerol binding, 0005096=GTPase activator activity" "0007480=imaginal disc-derived leg morphogenesis, 0043408=regulation of MAPK cascade, 0043547=positive regulation of GTPase activity, 0034334=adherens junction maintenance, 0043087=regulation of GTPase activity, 0016337=single organismal cell-cell adhesion, 0048749=compound eye development" "RhoGAP5A, CG3208, RhoGAP" "IPR008936=Rho GTPase activation protein, IPR000980=SH2 domain, IPR020454=Diacylglycerol/phorbol-ester binding, IPR000198=Rho GTPase-activating protein domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR017356=N-chimaerin" CG3208 16-Dec-15 2015_12 "ENSDARG00000011845,ENSDARG00000032493(chn1)" YBR260C(RGD1) WBGene00015267(chin-1) "ENSXETG00000015003(CHN1),ENSXETG00000012047(CHN2)" "ENSMUSG00000004633(Chn2),ENSMUSG00000056486(Chn1)" "ENSG00000128656(CHN1),ENSG00000106069(CHN2)" "viable,fertile,planar polarity defective" FBgn0032295 CG12299 http://flybase.net/reports/FBgn0032295.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG12299 16-Dec-15 2015_12 YNL027W(CRZ1) DRSC23611 EK 0.574095059 0.093929516 3.669384071 -2.502723193 0.237569401 2.819134157 FBgn0050360 Mal-A6 Maltase A6 http://flybase.net/reports/FBgn0050360.html FBgn0033295 protein_coding_gene "0003824=catalytic activity, 0043169=cation binding" 0005975=carbohydrate metabolic process "CG30360, Drome_A6, mal_A6, CG8689" "IPR013781=Glycoside hydrolase, catalytic domain, IPR015902=Glycoside hydrolase, family 13, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily" CG30360 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable FBgn0267913 CR46194 http://flybase.net/reports/FBgn0267913.html non_protein_coding_gene CR46194 16-Dec-15 2015_12 FBgn0259951 Sfp24Ba Seminal fluid protein 24Ba http://flybase.net/reports/FBgn0259951.html protein_coding_gene "0004867=serine-type endopeptidase inhibitor activity, 0030414=peptidase inhibitor activity" "0045861=negative regulation of proteolysis, 0032504=multicellular organism reproduction" 0005615=extracellular space "CG42461, SFP24BA, Seminal fluid protein 24Ba" "IPR020901=Proteinase inhibitor I2, Kunitz, conserved site, IPR002223=Pancreatic trypsin inhibitor Kunitz domain" CG42461 16-Dec-15 2015_12 FBgn0017425 anon-68Ec anon-68Ec http://flybase.net/reports/FBgn0017425.html gene T3 16-Dec-15 2015_12 FBgn0000127 Ars-region5 Autonomous replicating sequence region 5 http://flybase.net/reports/FBgn0000127.html region "Ars5, BgHS500, Ars sequence 5" 16-Dec-15 2015_12 FBgn0259868 Su(Ste):CR42437 Su(Ste):CR42437 http://flybase.net/reports/FBgn0259868.html non_protein_coding_gene CR42437 CR42437 16-Dec-15 2015_12 FBgn0036761 MED19 Mediator complex subunit 19 http://flybase.net/reports/FBgn0036761.html protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0008134=transcription factor binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter" 0016592=mediator complex "Med19, CG5546" "IPR019403=Mediator complex, subunit Med19, metazoa" CG5546 16-Dec-15 2015_12 "ENSDARG00000037392(LOC100334968),ENSDARG00000009472(med19b)" WBGene00007019(mdt-19) ENSMUSG00000027080(Med19) ENSG00000156603(MED19) "lethal - all die during pupal stage,lethal,visible,lethal - all die during embryonic stage,germline clone,maternal effect,cell lethalcell lethal,somatic clone,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "anterior pupal spiracle,maxillary palpus,dorsal pedicellar sensillum campaniformium,somatic clone - Minute background" DRSC10516 IK -1.047498301 2.637731814 0.46131678 0.636877539 3.906288687 2.161548203 FBgn0002459 l(3)SG12 lethal (3) SG12 http://flybase.net/reports/FBgn0002459.html gene l(3)J151 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0067353 l(3)95EFc lethal (3) 95EFc http://flybase.net/reports/FBgn0067353.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267263 CR45699 http://flybase.net/reports/FBgn0267263.html non_protein_coding_gene CR45699 16-Dec-15 2015_12 FBgn0037468 CG1943 http://flybase.net/reports/FBgn0037468.html protein_coding_gene 0048190=wing disc dorsal/ventral pattern formation CG1943 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0024214 l(3)E22 lethal (3) E22 http://flybase.net/reports/FBgn0024214.html gene 16-Dec-15 2015_12 lethal FBgn0266738 CR45211 http://flybase.net/reports/FBgn0266738.html non_protein_coding_gene CR45211 16-Dec-15 2015_12 FBgn0028986 Spn38F Serpin 38F http://flybase.net/reports/FBgn0028986.html FBgn0032892 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0050829=defense response to Gram-negative bacterium, 0010951=negative regulation of endopeptidase activity, 0032504=multicellular organism reproduction, 0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis" 0005615=extracellular space "Spn3, sp3, serpin 3, Sp3, Spn38F, CG9334, Serine protease inhibitor 3" "IPR023796=Serpin domain, IPR000215=Serpin family" CG9334 16-Dec-15 2015_12 "ENSDARG00000070396(serpinb1l2),ENSDARG00000055416(serpinb1),ENSDARG00000055431,ENSDARG00000057263(zgc:173729),ENSDARG00000059873,ENSDARG00000039849,ENSDARG00000014556" "ENSXETG00000027588(serpinb6),ENSXETG00000027590(BC087996.1),ENSXETG00000025592()" "ENSG00000206073(SERPINB4),ENSG00000057149(SERPINB3),ENSG00000197641(SERPINB13),ENSG00000166634(SERPINB12),ENSG00000166396(SERPINB7),ENSG00000117601(SERPINC1)" viable FBgn0027376 rha rha http://flybase.net/reports/FBgn0027376.html FBgn0044579 protein_coding_gene 0005694=chromosome "CG11908, anon-WO0140519.50, RADHA" IPR022136=Domain of unknown function DUF3668 CG11908 16-Dec-15 2015_12 ENSMUSG00000048799(Cep120) "viable,fertile" FBgn0053409 5SrRNA:CR33409 5SrRNA:CR33409 http://flybase.net/reports/FBgn0053409.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33409 CR33409 16-Dec-15 2015_12 FBgn0065365 l(2)SH1722 lethal (2) SH1722 http://flybase.net/reports/FBgn0065365.html gene l(2)SH2 1722 16-Dec-15 2015_12 "lethal,recessive" FBgn0261554 CG42672 http://flybase.net/reports/FBgn0261554.html "FBgn0050386, FBgn0050387, FBgn0034615, FBgn0034616" protein_coding_gene "CG10074, CG30387, CG30386, CG15665" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR011646=KAP family P-loop domain, IPR013761=Sterile alpha motif/pointed domain" CG42672 16-Dec-15 2015_12 "ENSDARG00000017338(kidins220b),ENSDARG00000031240(kidins220a)" WBGene00006490(tag-144) ENSXETG00000008271(KIDINS220) ENSMUSG00000036333(Kidins220) ENSG00000134313(KIDINS220) DRSC04256 IEK -1.378880952 -6.427472136 -1.688549914 -6.668325594 -5.98001899 -5.378363508 FBgn0263380 CR43432 http://flybase.net/reports/FBgn0263380.html non_protein_coding_gene chr3L:14942577..14942904 CR43432 16-Dec-15 2015_12 FBgn0010729 l(3)00835 lethal (3) 00835 http://flybase.net/reports/FBgn0010729.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011599 gui guillotined http://flybase.net/reports/FBgn0011599.html gene 0007409=axonogenesis 16-Dec-15 2015_12 "chordotonal organ & axon | lateral,RP1 motor neuron,RP3 motor neuron" FBgn0002462 l(3)SG15 lethal (3) SG15 http://flybase.net/reports/FBgn0002462.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" imaginal disc FBgn0010551 Phb2 Prohibitin 2 http://flybase.net/reports/FBgn0010551.html "FBgn0034395, FBgn0062207, FBgn0067804" protein_coding_gene "0016020=membrane, 0005811=lipid particle, 0005739=mitochondrion" "phb2, l (2) 03709, anon-WO0118547.157, l(2)03709, anon-WO02079478.4, CG15081, lethal (2) 03709" "IPR001107=Band 7 protein, IPR000163=Prohibitin" CG15081 16-Dec-15 2015_12 ENSDARG00000002202(zgc:86841) YGR231C(PHB2) WBGene00004015(phb-2) ENSXETG00000023919(phb2) ENSMUSG00000004264(Phb2) ENSG00000215021(PHB2) "lethal,partially lethal - majority die,visible,recessive" mesothoracic tergum DRSC06512 IE -2.195367449 -2.532544615 -2.073026724 -1.834112871 0.215769438 -0.378994529 FBgn0028936 NimB5 Nimrod B5 http://flybase.net/reports/FBgn0028936.html FBgn0032539 protein_coding_gene 0042742=defense response to bacterium 0005576=extracellular region "NimB5, nimB5, nimrod B5, BG:DS00180.9, CG16873" "IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000742=EGF-like domain, IPR013032=EGF-like, conserved site" CG16873 16-Dec-15 2015_12 "ENSDARG00000038208,ENSDARG00000028168" viable FBgn0062270 huc29DE hydroxyurea- and (or) caffeine-sensitive 29DE http://flybase.net/reports/FBgn0062270.html gene "Huc-29DE, huc, huc[29DE], HU- or caffeine-sensitive 29DE, HU- and caffeine-dependent 29D-E" 16-Dec-15 2015_12 "chemical sensitive,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,drug conditional,ommatidium,eye photoreceptor cell" FBgn0004757 l(3)89Bj lethal (3) 89Bj http://flybase.net/reports/FBgn0004757.html gene 16-Dec-15 2015_12 lethal FBgn0267602 CR45940 http://flybase.net/reports/FBgn0267602.html non_protein_coding_gene CR45940 16-Dec-15 2015_12 FBgn0011794 l(3)j6C3 lethal (3) j6C3 http://flybase.net/reports/FBgn0011794.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003871 ttr tetrapter http://flybase.net/reports/FBgn0003871.html gene tetraptera 16-Dec-15 2015_12 haltere FBgn0032058 CG9289 http://flybase.net/reports/FBgn0032058.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "glutactin-like, CT26467" "IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG9289 16-Dec-15 2015_12 "viable,fertile" FBgn0034063 CG8389 http://flybase.net/reports/FBgn0034063.html protein_coding_gene 0015355=secondary active monocarboxylate transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8389 16-Dec-15 2015_12 "viable,fertile" DRSC07158 IEK 2.121757431 0.614778668 1.640739893 2.612725654 2.862972285 -0.622564141 FBgn0266628 CR45135 http://flybase.net/reports/FBgn0266628.html non_protein_coding_gene CR45135 16-Dec-15 2015_12 FBgn0267683 CR46019 http://flybase.net/reports/FBgn0267683.html non_protein_coding_gene CR46019 16-Dec-15 2015_12 FBgn0033216 CG1946 http://flybase.net/reports/FBgn0033216.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" IPR007130=Diacylglycerol acyltransferase CG1946 16-Dec-15 2015_12 "ENSDARG00000019228(mogat2),ENSDARG00000018846(dgat2),ENSDARG00000003635(LOC565116),ENSDARG00000070072" YOR245C(DGA1) "WBGene00019464(K07B1.4),WBGene00021818(Y53G8B.2),WBGene00020910(W01A11.2),WBGene00010296(F59A1.10)" "ENSXETG00000002935(mogat1),ENSXETG00000004012(mogat2),ENSXETG00000015062(),ENSXETG00000023190(),ENSXETG00000025317(dgat2)" "ENSMUSG00000052396(Mogat2),ENSMUSG00000012187(Mogat1),ENSMUSG00000030747(Dgat2),ENSMUSG00000067597(Dgat2l6),ENSMUSG00000031220(Awat2),ENSMUSG00000015665(Awat1)" "ENSG00000166391(MOGAT2),ENSG00000124003(MOGAT1),ENSG00000062282(DGAT2),ENSG00000106384(MOGAT3),ENSG00000204195(AWAT1),ENSG00000184210(DGAT2L6),ENSG00000147160(AWAT2)" viable FBgn0011014 l(3)s1922 lethal (3) s1922 http://flybase.net/reports/FBgn0011014.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000369 cr-b cream b http://flybase.net/reports/FBgn0000369.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0259573 B0176 http://flybase.net/reports/FBgn0259573.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing,wing vein,chaeta,ectopic" FBgn0040111 l(3)tk11 lethal (3) tk11 http://flybase.net/reports/FBgn0040111.html gene tk11 16-Dec-15 2015_12 "lethal,recessive" FBgn0037572 CG11698 http://flybase.net/reports/FBgn0037572.html protein_coding_gene IPR007999=Protein of unknown function DUF745 CG11698 16-Dec-15 2015_12 viable FBgn0259364 C596 http://flybase.net/reports/FBgn0259364.html gene 16-Dec-15 2015_12 visible wing FBgn0262338 mir-2499 mir-2499 stem loop http://flybase.net/reports/FBgn0262338.html miRNA_gene "CR43045, dme-mir-2499" CR43045 16-Dec-15 2015_12 viable FBgn0259456 EP-820 http://flybase.net/reports/FBgn0259456.html gene 16-Dec-15 2015_12 visible "wing vein,wing,chaeta" FBgn0052319 CG32319 http://flybase.net/reports/FBgn0052319.html FBgn0035221 protein_coding_gene 0008080=N-acetyltransferase activity 0006473=protein acetylation CG12083 "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG32319 16-Dec-15 2015_12 YPR051W(MAK3) ENSXETG00000011990(NAA30) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0026657 l(2)18E4 lethal (2) 18E4 http://flybase.net/reports/FBgn0026657.html gene 0007298=border follicle cell migration 16-Dec-15 2015_12 "lethal,recessive" "border follicle cell,somatic clone" FBgn0263075 l(3)10477 lethal (3) 10477 http://flybase.net/reports/FBgn0263075.html FBgn0010943 gene 16-Dec-15 2015_12 partially lethal - majority die FBgn0260397 Su(var)3-3 Suppressor of variegation 3-3 http://flybase.net/reports/FBgn0260397.html "FBgn0259698, FBgn0003594, FBgn0036954, FBgn0036955" protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity, 0003677=DNA binding, 0032453=histone demethylase activity (H3-K4 specific)" "0008593=regulation of Notch signaling pathway, 0048477=oogenesis, 0006325=chromatin organization, 0006355=regulation of transcription, DNA-templated, 0034720=histone H3-K4 demethylation, 0055114=oxidation-reduction process, 0016458=gene silencing, 0070828=heterochromatin organization, 0007474=imaginal disc-derived wing vein specification" "0005634=nucleus, 0017053=transcriptional repressor complex" "Flavoprotein, SU(VAR)3-3, CG17149, Dmel\LSD1, Suvar(3)3, lsd1, dLSD1, Hdm, Lsd1, Histone demethylase, dLsd1, Dmel/HDM, Su-var(3)3, histone lysine-specific demethylase 1, Dmel/LSD1" "IPR002937=Amine oxidase, IPR009057=Homeodomain-like, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR007526=SWIRM domain, IPR017366=Histone lysine-specific demethylase" CG17149 16-Dec-15 2015_12 "ENSDARG00000060679(kdm1a),ENSDARG00000060722" YMR020W(FMS1) "WBGene00005010(spr-5),WBGene00000137(amx-1),WBGene00011615(lsd-1)" ENSXETG00000003698(KDM1A) ENSMUSG00000036940(Kdm1a) ENSG00000004487(KDM1A) DRSC10250 K 0.033335981 -0.026503002 0.65577557 0.80469299 -1.729937607 -0.311198969 FBgn0005549 l(3)73Bd lethal (3) 73Bd http://flybase.net/reports/FBgn0005549.html gene 16-Dec-15 2015_12 lethal FBgn0001594 l(1)carot11 lethal (1) carot11 http://flybase.net/reports/FBgn0001594.html gene 16-Dec-15 2015_12 lethal FBgn0033252 CG12769 http://flybase.net/reports/FBgn0033252.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG12769 16-Dec-15 2015_12 ENSDARG00000037068(ikzf4) WBGene00019960(ztf-16) "ENSXETG00000015684(znfn1a1),ENSXETG00000009449(IKZF4),ENSXETG00000003127(IKZF2),ENSXETG00000015152(IKZF3)" "ENSG00000030419(IKZF2),ENSG00000123411(IKZF4),ENSG00000185811(IKZF1),ENSG00000161405(IKZF3)" viable FBgn0031033 CG14219 http://flybase.net/reports/FBgn0031033.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG14219 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" FBgn0265428 CR44340 http://flybase.net/reports/FBgn0265428.html non_protein_coding_gene CR44340 16-Dec-15 2015_12 FBgn0266997 ë±-Cat::shg ë±-Cat::shg http://flybase.net/reports/FBgn0266997.html "FBgn0266760, FBgn0065043" engineered_fusion_gene "DE-cadherin::alpha-Catenin, shg::alpha-Cat, DEcad::alphaCat, E-Cadherin:alpha-Catenin, DEcad-alpha-Cat, alpha-catenin, DE-cadherin" 16-Dec-15 2015_12 FBgn0017450 abof about face http://flybase.net/reports/FBgn0017450.html gene 0007409=axonogenesis 16-Dec-15 2015_12 "chordotonal organ & axon | lateral,commissure,longitudinal connective" FBgn0030376 CG2750 http://flybase.net/reports/FBgn0030376.html FBgn0044758 protein_coding_gene anon-WO0140519.124 CG2750 16-Dec-15 2015_12 "viable,fertile" FBgn0033458 CG18446 http://flybase.net/reports/FBgn0033458.html protein_coding_gene 0046872=metal ion binding "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG18446 16-Dec-15 2015_12 ENSMUSG00000016503(Gtf3a) FBgn0033480 mRpL42 mitochondrial ribosomal protein L42 http://flybase.net/reports/FBgn0033480.html FBgn0047062 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005763=mitochondrial small ribosomal subunit, 0005761=mitochondrial ribosome" "BcDNA:RE72116, mitochondrial ribosomal protein S32, MRP-S32, MRPL31, mRpS32, CG12921" "IPR019346=Ribosomal protein S32, mitochondrial" CG12921 16-Dec-15 2015_12 WBGene00003066(lpl-1) ENSMUSG00000062981(Mrpl42) ENSG00000198015(MRPL42) "viable,visible" trichogen cell DRSC06235 K -0.463332973 -0.664110389 -0.623800943 0.100174478 1.594816047 1.992712776 FBgn0038725 CG6184 http://flybase.net/reports/FBgn0038725.html protein_coding_gene IPR027295=Quinonprotein alcohol dehydrogenase-like domain CG6184 16-Dec-15 2015_12 viable FBgn0025562 anon-36Aa anon-36Aa http://flybase.net/reports/FBgn0025562.html gene cDNA I 16-Dec-15 2015_12 FBgn0065591 l(2)SH0901 lethal (2) SH0901 http://flybase.net/reports/FBgn0065591.html gene l(2)SH2 0901 16-Dec-15 2015_12 "lethal,recessive" FBgn0039767 CG2218 http://flybase.net/reports/FBgn0039767.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0034450=ubiquitin-ubiquitin ligase activity" 0016567=protein ubiquitination 0005634=nucleus "BT044264.1, UIP5" "IPR003613=U box domain, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG2218 16-Dec-15 2015_12 ENSDARG00000058563(LOC402829) ENSXETG00000027330(Q6DFT1_XENTR) ENSMUSG00000027300(Ubox5) ENSG00000185019(UBOX5) viable FBgn0015386 en::ftz en::ftz http://flybase.net/reports/FBgn0015386.html engineered_fusion_gene 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" denticle belt FBgn0026261 bonsai bonsai http://flybase.net/reports/FBgn0026261.html FBgn0034749 protein_coding_gene 0003735=structural constituent of ribosome "0040008=regulation of growth, 0006412=translation" "0005763=mitochondrial small ribosomal subunit, 0005739=mitochondrion" "DmMRPS15, MRP-S15, mRpS15, Bonsai, CG4207" "IPR009068=S15/NS1, RNA-binding, IPR000589=Ribosomal protein S15, IPR005290=Ribosomal protein S15, bacterial-type" CG4207 16-Dec-15 2015_12 ENSDARG00000031153 WBGene00010624(K07A12.7) ENSXETG00000005257(mrps15) " embryonic stage -- adult stage , embryonic stage | extended germ band , larval stage , embryonic stage | late , embryonic stage | early " " anterior midgut inclusive primordium && posterior midgut inclusive primordium

, larval midgut

, embryonic midgut | restricted

, organism | ubiquitous

" "visible,recessive,size defective,developmental rate defective,lethal - all die before end of larval stage,partially,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" "adult,anterior larval midgut & mitochondrion,trichogen cell,mesothoracic tergum" FBgn0266540 CG45101 http://flybase.net/reports/FBgn0266540.html protein_coding_gene Dmel_SuUR_uORF CG45101 16-Dec-15 2015_12 FBgn0044081 E(rst)H42 E(rst)H42 http://flybase.net/reports/FBgn0044081.html gene 0001745=compound eye morphogenesis H42 16-Dec-15 2015_12 viable FBgn0003088 Pin Pin http://flybase.net/reports/FBgn0003088.html gene "Tac, Tack" 16-Dec-15 2015_12 "lethal,recessive,viable,visible,dominant" "macrochaeta,heat sensitive,mesothoracic bristle,metathoracic bristle,wing,female,scutellar bristle,thorax & macrochaeta,adult cuticle,cuticle" FBgn0265053 CR44168 http://flybase.net/reports/FBgn0265053.html non_protein_coding_gene CR44168 16-Dec-15 2015_12 FBgn0051088 CG31088 http://flybase.net/reports/FBgn0051088.html protein_coding_gene CG31088 16-Dec-15 2015_12 viable FBgn0003286 Rst(1)str Resistant to streptomycin http://flybase.net/reports/FBgn0003286.html gene "str-R, Resistance (1) streptomycin" 16-Dec-15 2015_12 chemical resistant ribosome FBgn0260046 33AA14 http://flybase.net/reports/FBgn0260046.html gene 16-Dec-15 2015_12 "visible,somatic clone" "wing,somatic clone" FBgn0028116 l(3)S063813 lethal (3) S063813 http://flybase.net/reports/FBgn0028116.html gene 0638/13 16-Dec-15 2015_12 "lethal,recessive" FBgn0031474 CG2991 http://flybase.net/reports/FBgn0031474.html protein_coding_gene 0008270=zinc ion binding "CT10107, CT42388" "IPR009457=Domain of unknown function DUF1084, IPR011016=Zinc finger, RING-CH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG2991 16-Dec-15 2015_12 viable FBgn0000917 fs(1)ne3 female sterile (1) no eggs 3 http://flybase.net/reports/FBgn0000917.html gene "fs(1)ne[3], ne3" 16-Dec-15 2015_12 "female sterile,recessive,female sterile germline-dependent" "endochorion,dorsal appendage,chorion,oocyte" FBgn0261843 pre-mod(mdg4)-W http://flybase.net/reports/FBgn0261843.html protein_coding_gene CG42775 "IPR007588=Zinc finger, FLYWCH-type" CG42775 16-Dec-15 2015_12 FBgn0038630 CG14305 http://flybase.net/reports/FBgn0038630.html protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG14305 16-Dec-15 2015_12 ENSDARG00000017994(si:dkey-11n6.4) "WBGene00044388(C27D6.11),WBGene00012638(Y38H8A.4),WBGene00015230(tag-344)" "ENSMUSG00000041566(Tssk1),ENSMUSG00000045521(Tssk2)" "ENSG00000212122(TSSK1B),ENSG00000206203(TSSK2)" viable DRSC14784 K -0.041856088 0.610597618 -0.185199853 0.252780545 1.538494444 -0.094858458 FBgn0005459 l(1)v459 lethal (1) v459 http://flybase.net/reports/FBgn0005459.html gene l(1)459 16-Dec-15 2015_12 FBgn0028029 l(3)S103012b lethal (3) S103012b http://flybase.net/reports/FBgn0028029.html gene "l(3)S103012, 1030/12" 16-Dec-15 2015_12 "lethal,recessive" FBgn0062591 Mod(var)1557 Mod(var)1557 http://flybase.net/reports/FBgn0062591.html gene 1557 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,partially lethal - majority die,recessive" FBgn0003739 Tpl Triplolethal http://flybase.net/reports/FBgn0003739.html gene "tpl, Triplo-lethal" 16-Dec-15 2015_12 FBgn0041716 srn stern http://flybase.net/reports/FBgn0041716.html gene 16-Dec-15 2015_12 "lethal,chemical resistant,dominant,recessive,melanotic mass phenotype,tumorigenic" "salivary gland,polytene chromosome,melanotic mass,embryonic/larval brain" FBgn0053012 CG33012 http://flybase.net/reports/FBgn0053012.html "FBgn0033719, FBgn0050041" protein_coding_gene "CG13161, CG30041" IPR007484=Peptidase M28 CG33012 16-Dec-15 2015_12 YBR074W() WBGene00015206(B0495.7) ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) viable FBgn0083984 CG34148 http://flybase.net/reports/FBgn0083984.html protein_coding_gene IPR029245=Protein of unknown function DUF4528 CG34148 16-Dec-15 2015_12 ENSDARG00000069240(zgc:162898) ENSG00000189227(C15orf61) FBgn0005132 l(1)Y8 lethal (1) Y8 http://flybase.net/reports/FBgn0005132.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0058292 CG40292 http://flybase.net/reports/FBgn0058292.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040877 CG12994 http://flybase.net/reports/FBgn0040877.html protein_coding_gene CG12994 16-Dec-15 2015_12 viable DRSC19514 IE -0.601459047 -1.978444665 1.602566356 -0.058730736 0.15757832 -0.632486273 FBgn0052360 tRNA:CR32360 transfer RNA:CR32360 http://flybase.net/reports/FBgn0052360.html FBgn0060158 tRNA_gene 0033420=CUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr3L.trna42-LeuCAG, tRNA:L:CAG:AE002602-d, AE002602.trna8-LeuCAG, CR32360" CR32360 16-Dec-15 2015_12 FBgn0027997 l(3)S123208 lethal (3) S123208 http://flybase.net/reports/FBgn0027997.html gene "1232/08, 1282/02, 0542/11" 16-Dec-15 2015_12 "lethal,recessive" FBgn0025129 su(RpII140Z36)S18 su(RpII140Z36)S18 http://flybase.net/reports/FBgn0025129.html gene Z36[S18] 16-Dec-15 2015_12 FBgn0250869 CG42240 http://flybase.net/reports/FBgn0250869.html protein_coding_gene CG15893 CG42240 16-Dec-15 2015_12 FBgn0013403 anon-14Bb anon-14Bb http://flybase.net/reports/FBgn0013403.html FBgn0014079 gene 16-Dec-15 2015_12 adult stage FBgn0039948 CG17865 http://flybase.net/reports/FBgn0039948.html protein_coding_gene 16-Dec-15 2015_12 FBgn0036329 CG11262 http://flybase.net/reports/FBgn0036329.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane IPR004680=Citrate transporter-like domain CG11262 16-Dec-15 2015_12 viable FBgn0030122 CG16892 http://flybase.net/reports/FBgn0030122.html protein_coding_gene 0006913=nucleocytoplasmic transport "0005643=nuclear pore, 0012505=endomembrane system" Aladin "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain" CG16892 16-Dec-15 2015_12 ENSDARG00000019547(aaas) ENSXETG00000012664(AAAS) ENSMUSG00000036678(Aaas) ENSG00000094914(AAAS) "viable,fertile" FBgn0002051 l(2)37Fd lethal (2) 37Fd http://flybase.net/reports/FBgn0002051.html gene l(2)OE55 16-Dec-15 2015_12 lethal FBgn0013706 mt:tRNA:S:UCN mitochondrial serine UCN tRNA http://flybase.net/reports/FBgn0013706.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "serine[UCN] tRNA, mtdbD00006311, tRNA[Ser(UCN)], mt-tRNA[Ser] (UGA), CR34091, tRNA-Ser, tRNA[Ser]" CR34091 16-Dec-15 2015_12 FBgn0003278 RpI135 RNA polymerase I 135kD subunit http://flybase.net/reports/FBgn0003278.html FBgn0021812 protein_coding_gene "0032549=ribonucleoside binding, 0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0022008=neurogenesis, 0006360=transcription from RNA polymerase I promoter" "0005634=nucleus, 0005736=DNA-directed RNA polymerase I complex" "CG4033, RP135, l(2)k16513, RPI135, DmRP135, RNA polymerase I, Rpl135, RpIII135" "IPR015712=DNA-directed RNA polymerase, subunit 2, IPR007121=RNA polymerase, beta subunit, conserved site, IPR007642=RNA polymerase Rpb2, domain 2, IPR007641=RNA polymerase Rpb2, domain 7, IPR007120=DNA-directed RNA polymerase, subunit 2, domain 6, IPR007645=RNA polymerase Rpb2, domain 3, IPR009674=RNA polymerase I, Rpa2 specific, IPR007644=RNA polymerase, beta subunit, protrusion" CG4033 16-Dec-15 2015_12 "ENSDARG00000068942,ENSDARG00000068626" YPR010C(RPA135) WBGene00008781(F14B4.3) ENSXETG00000013749(POLR1B) ENSMUSG00000027395(Polr1b) ENSG00000125630(POLR1B) adult stage "viable,lethal,developmental rate defective,decreased cell size,somatic clone,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,embryonic/larval fat body,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0014071 TART-element\gag TART-open reading frame 1 http://flybase.net/reports/FBgn0014071.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "0000781=chromosome, telomeric region, 0005634=nucleus" "TART[mel] Gag, TART ORF1, TART-element\ORF1, TART A ORF1, TART gag, TART-repeat\ORF1, ORF1, TART Gag, gag" "IPR006579=Pre-C2HC domain, IPR001878=Zinc finger, CCHC-type" 16-Dec-15 2015_12 FBgn0030101 CG12118 http://flybase.net/reports/FBgn0030101.html protein_coding_gene 0009235=cobalamin metabolic process IPR019362=Methylmalonic aciduria and homocystinuria type D protein CG12118 16-Dec-15 2015_12 "ENSDARG00000005870(mmadhc),ENSDARG00000041602(zgc:92335)" ENSXETG00000004524(TNeu087l22.1) ENSMUSG00000026766(Mmadhc) viable FBgn0030373 CG12721 http://flybase.net/reports/FBgn0030373.html FBgn0062990 protein_coding_gene BcDNA:RE60404 CG12721 16-Dec-15 2015_12 "viable,female sterile" FBgn0003050 pod-foot pod foot http://flybase.net/reports/FBgn0003050.html gene pdf 16-Dec-15 2015_12 "visible,recessive,fertile,viable" "pretarsus,tarsal segment 3,tarsal segment 4,tarsal segment" FBgn0050469 Ir52b Ionotropic receptor 52b http://flybase.net/reports/FBgn0050469.html FBgn0034024 protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 52b, CG12961, IF52b, CG30469, DmelIR52b, IR52b" CG30469 16-Dec-15 2015_12 viable FBgn0039277 CG13650 http://flybase.net/reports/FBgn0039277.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain" CG13650 16-Dec-15 2015_12 viable FBgn0024362 CG11412 http://flybase.net/reports/FBgn0024362.html protein_coding_gene 0008080=N-acetyltransferase activity 0016573=histone acetylation "DmAAF45606, EG:8D8.6, NAA30" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG11412 16-Dec-15 2015_12 WBGene00015074(B0238.10) ENSMUSG00000036282(Naa30) ENSG00000139977(NAA30) "viable,fertile" FBgn0039398 CG14540 http://flybase.net/reports/FBgn0039398.html protein_coding_gene IPR006990=Tweety CG14540 16-Dec-15 2015_12 viable DRSC14884 IEK -1.564750473 -1.524808493 -1.861985442 0.676072232 2.444436797 1.002984555 FBgn0259715 CG42369 http://flybase.net/reports/FBgn0259715.html "FBgn0031810, FBgn0031809, FBan0009511" protein_coding_gene "CG9508, CT26922, CG9511, CG13981, CG33295" CG42369 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0267957 CR46237 http://flybase.net/reports/FBgn0267957.html non_protein_coding_gene lincRNA.294 CR46237 16-Dec-15 2015_12 FBgn0000552 Edg84A Ecdysone-dependent gene 84A http://flybase.net/reports/FBgn0000552.html "FBgn0004776, FBtr0081688, FBpp0081186" protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008011=structural constituent of pupal chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "cc1, cuticle-like cluster, unnamed, EDG84, BG:DS00004.8, ecdysone-dependent gene-84A-1, EDG84A, EDG-84, EDG-84A, CG2345, Edg84, cuticle cluster 1, DmelEDG84A, DM-EDG84" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG2345 16-Dec-15 2015_12 prepupal stage epidermis

"viable,visible" trichogen cell FBgn0004565 l(3)63Da lethal (3) 63Da http://flybase.net/reports/FBgn0004565.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029676 HIP-R Hsc/Hsp70-interacting protein related http://flybase.net/reports/FBgn0029676.html "FBgn0052789, FBgn0025274" protein_coding_gene "0031072=heat shock protein binding, 0051087=chaperone binding, 0030544=Hsp70 protein binding" 0070389=chaperone cofactor-dependent protein refolding "0005829=cytosol, 0043234=protein complex" "CG2947, anon-fast-evolving-1A9, anon-EST:fe1A9, Hip, HIP-R" "IPR019734=Tetratricopeptide repeat, IPR013105=Tetratricopeptide repeat 2, IPR011990=Tetratricopeptide-like helical domain, IPR006636=Heat shock chaperonin-binding, IPR013026=Tetratricopeptide repeat-containing domain" CG2947 16-Dec-15 2015_12 ENSDARG00000021973(st13) WBGene00011735(T12D8.8) ENSXETG00000022971(st13) ENSMUSG00000022403(St13) "ENSG00000100380(ST13),ENSG00000212789" FBgn0060983 l(3)S028304 lethal (3) S028304 http://flybase.net/reports/FBgn0060983.html gene 0283/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0260942 bond james bond http://flybase.net/reports/FBgn0260942.html "FBgn0083096, FBgn0038985" protein_coding_gene 0009922=fatty acid elongase activity "0051225=spindle assembly, 0042761=very long-chain fatty acid biosynthetic process, 0030497=fatty acid elongation, 0007110=meiosis I cytokinesis, 0000915=actomyosin contractile ring assembly, 0007111=meiosis II cytokinesis, 0007112=male meiosis cytokinesis, 0000212=meiotic spindle organization" 0016021=integral component of membrane "bond, James bond, CG6921" IPR002076=ELO family CG6921 16-Dec-15 2015_12 "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" FBgn0034569 dgt3 dim ë_-tubulin 3 http://flybase.net/reports/FBgn0034569.html protein_coding_gene "0007088=regulation of mitotic nuclear division, 0007052=mitotic spindle organization" "0070652=HAUS complex, 0005875=microtubule associated complex" "dim, Dgt3, CG3221" CG3221 16-Dec-15 2015_12 viable FBgn0025591 His2Bë¬ Histone H2B pseudogene http://flybase.net/reports/FBgn0025591.html pseudogene_attribute PsiH2B 16-Dec-15 2015_12 FBgn0265062 CR44173 http://flybase.net/reports/FBgn0265062.html non_protein_coding_gene "CG44173, lincRNA.809" CR44173 16-Dec-15 2015_12 FBgn0028131 l(3)S051309 lethal (3) S051309 http://flybase.net/reports/FBgn0028131.html gene 0513/09 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0052404 Cpr65Aw Cuticular protein 65Aw http://flybase.net/reports/FBgn0052404.html FBgn0035684 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "C32404, CG10461, CG32404, DmelCpr65Aw" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG32404 16-Dec-15 2015_12 viable FBgn0039479 CG14257 http://flybase.net/reports/FBgn0039479.html protein_coding_gene CG14257 16-Dec-15 2015_12 viable FBgn0002306 sas stranded at second http://flybase.net/reports/FBgn0002306.html protein_coding_gene 0004872=receptor activity "0002168=instar larval development, 0007411=axon guidance" "0016324=apical plasma membrane, 0005887=integral component of plasma membrane" "SAS, Stranded at Second, responsible for dominant phenotype, CG2507, Sas, stranded-at-second, Stranded-at-second, stranded at Second, l(3)84Cd, Stranded at second, rfd" "IPR003961=Fibronectin type III, IPR013783=Immunoglobulin-like fold, IPR001007=VWFC domain" CG2507 16-Dec-15 2015_12 " adult stage , embryonic stage | stage 15,16 , larval stage | third instar , larval stage , embryonic stage | stage 12-16 , embryonic stage | stage 15-16 " " mouthpart

, trachea

, imaginal disc

, wing

, epidermis

, eye

, embryonic/larval esophagus

, embryonic/larval foregut

, embryonic/larval pharynx

, embryonic/larval proventriculus

, reproductive system

, leg

, embryonic/larval hindgut

" "some die during larval stage,partially lethal - majority die,viable,fertile,lethal - all die before end of larval stage,polyphasic,cold sensitive,lethal,recessive,neuroanatomy defective" "embryonic/larval cuticle,embryonic/larval trachea,embryonic/larval tracheal system,longitudinal connective,anterior commissure,longitudinal connective | embryonic stage 16" FBgn0044087 E(rst)E370 E(rst)E370 http://flybase.net/reports/FBgn0044087.html gene 0001745=compound eye morphogenesis E370 16-Dec-15 2015_12 viable "eye,retina" FBgn0266951 CR45402 http://flybase.net/reports/FBgn0266951.html non_protein_coding_gene CR45402 16-Dec-15 2015_12 FBgn0060964 l(3)S032110 lethal (3) S032110 http://flybase.net/reports/FBgn0060964.html gene 0321/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0026150 ApepP Aminopeptidase P http://flybase.net/reports/FBgn0026150.html protein_coding_gene "0070006=metalloaminopeptidase activity, 0004177=aminopeptidase activity" 0006508=proteolysis 0005829=cytosol "DAP-P, AP-P, Apep[P], Daminopep-p, CG6291" "IPR000994=Peptidase M24, structural domain, IPR028980=Creatinase/Aminopeptidase P, N-terminal, IPR000587=Creatinase, N-terminal, IPR029149=Creatinase/Aminopeptidase P/Spt16, N-terminal" CG6291 16-Dec-15 2015_12 ENSDARG00000029011(xpnpep1) YLL029W(FRA1) "WBGene00000155(app-1),WBGene00021555(Y45G5AM.2)" ENSXETG00000007460(XPNPEP2) ENSMUSG00000025027(Xpnpep1) ENSG00000108039(XPNPEP1) FBgn0264485 CR43893 http://flybase.net/reports/FBgn0264485.html non_protein_coding_gene CR43893 16-Dec-15 2015_12 FBgn0038380 CG14877 http://flybase.net/reports/FBgn0038380.html protein_coding_gene "0004872=receptor activity, 0004383=guanylate cyclase activity" "IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region" CG14877 16-Dec-15 2015_12 WBGene00020132 ENSXETG00000025388() "partially lethal - majority die,some die during pupal stage" FBgn0027932 Akap200 A kinase anchor protein 200 http://flybase.net/reports/FBgn0027932.html "FBgn0061414, FBgn0062168, FBgn0062223" protein_coding_gene 0051018=protein kinase A binding "0090175=regulation of establishment of planar polarity, 0046580=negative regulation of Ras protein signal transduction, 0008104=protein localization, 0048102=autophagic cell death, 0048149=behavioral response to ethanol, 0035071=salivary gland cell autophagic cell death" "0005737=cytoplasm, 0005811=lipid particle, 0005886=plasma membrane" "AKAP200, Akap 200, akap200, anon-WO0118547.213, EP(2)2254, MESR2, dpo, BcDNA:LP02734, A kinase anchor protein, anon-WO0118547.134, CG13388, DAKAP200" CG13388 16-Dec-15 2015_12 " embryonic stage -- adult stage , adult stage " adult head

"viable,reduced,lethal,recessive,visible,wild-type,fertile,female fertile,hyperactive,conditional,chemical resistant" "mesothoracic tergum & chaeta | supernumeraryN22-14),nurse cell,egg chamber,mesothoracic tergum & macrochaeta | supernumeraryN22-14),inner nurse cell ring canal rim,outer nurse cell ring canal rim,antenna,wing vein,wing" FBgn0263992 CR43735 http://flybase.net/reports/FBgn0263992.html non_protein_coding_gene CR43735 16-Dec-15 2015_12 FBgn0031283 CG15880 http://flybase.net/reports/FBgn0031283.html protein_coding_gene IPR019402=Frag1/DRAM/Sfk1 CG15880 16-Dec-15 2015_12 viable FBgn0053407 5SrRNA:CR33407 5SrRNA:CR33407 http://flybase.net/reports/FBgn0053407.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33407 CR33407 16-Dec-15 2015_12 FBgn0086444 l(2)37Cb lethal (2) 37Cb http://flybase.net/reports/FBgn0086444.html "FBgn0002030, FBgn0032759" protein_coding_gene "0003724=RNA helicase activity, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0003676=nucleic acid binding" "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome" "cg10689, CG10689, l(2)E104, Cb" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011709=Domain of unknown function DUF1605, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR007502=Helicase-associated domain, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650=Helicase, C-terminal" CG10689 16-Dec-15 2015_12 ENSDARG00000013150(dhx16) WBGene00003392(mog-4) ENSXETG00000024069(DHX16) ENSMUSG00000024422(Dhx16) "ENSG00000204560(DHX16),ENSG00000206397,ENSG00000206486" FBgn0260873 CG42583 http://flybase.net/reports/FBgn0260873.html protein_coding_gene CG42583 16-Dec-15 2015_12 FBgn0034407 DptB Diptericin B http://flybase.net/reports/FBgn0034407.html FBgn0064827 protein_coding_gene "0006959=humoral immune response, 0050830=defense response to Gram-positive bacterium, 0019731=antibacterial humoral response" 0005615=extracellular space "dptB, Diptericin, CG10794, diptericin B, dptlp, Diptericin-B, 147473_at, DiptericinB, BcDNA:RH29451, diptericin-like protein, DiptB, Diptercin B, dpt B, Dpt, Diptericin B" "IPR005521=Attacin, C-terminal" CG10794 16-Dec-15 2015_12 viable FBgn0017361 l(3)C106 lethal (3) C106 http://flybase.net/reports/FBgn0017361.html gene C106 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0011391 l(3)j6B4 lethal (3) j6B4 http://flybase.net/reports/FBgn0011391.html gene l(3)J6B4 16-Dec-15 2015_12 "lethal,recessive" FBgn0032801 CG10165 http://flybase.net/reports/FBgn0032801.html protein_coding_gene 0016021=integral component of membrane "IPR006593=Cytochrome b561/ferric reductase transmembrane, IPR004877=Cytochrome b561 domain" CG10165 16-Dec-15 2015_12 "ENSDARG00000044114(cyb561d2),ENSDARG00000055295(cyb561d1)" ENSXETG00000025206(Cyb561d2) "ENSG00000174151(CYB561D1),ENSG00000114395(CYB561D2)" viable FBgn0044871 Gos28 "Golgi SNARE, 28 kDa" http://flybase.net/reports/FBgn0044871.html FBgn0038637 protein_coding_gene 0005484=SNAP receptor activity "0006906=vesicle fusion, 0006888=ER to Golgi vesicle-mediated transport, 0006891=intra-Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport, 0048209=regulation of vesicle targeting, to, from or within Golgi, 0048193=Golgi vesicle transport" "0016021=integral component of membrane, 0000138=Golgi trans cisterna, 0031201=SNARE complex, 0000139=Golgi membrane, 0016020=membrane, 0005801=cis-Golgi network" "CG7700, gos28, FSG28, Gos28, dgos28, dGos28, GOS28" "IPR023601=Golgi SNAP receptor complex, subunit 1" CG7700 16-Dec-15 2015_12 ENSDARG00000026654(gosr1) YHL031C(GOS1) WBGene00017273(gos-28) ENSXETG00000008037(gosr1) ENSMUSG00000010392(Gosr1) ENSG00000108587(GOSR1) "viable,fertile" DRSC22859 E 0.906258817 0.626511151 0.87016003 2.004989606 0.936239691 1.26130472 FBgn0085345 CG34316 http://flybase.net/reports/FBgn0085345.html protein_coding_gene "Dm_3R:60797, JHBP" IPR010562=Haemolymph juvenile hormone binding CG34316 16-Dec-15 2015_12 FBgn0005442 l(1)v139 lethal (1) v139 http://flybase.net/reports/FBgn0005442.html gene l(1)139 16-Dec-15 2015_12 FBgn0035440 CG14969 http://flybase.net/reports/FBgn0035440.html protein_coding_gene IPR019172=Osteopetrosis-associated transmembrane protein 1 precursor CG14969 16-Dec-15 2015_12 ENSDARG00000069808(si:ch73-257c13.3) WBGene00009627(F42A8.3) ENSXETG00000014857(OSTM1) ENSMUSG00000038280(Ostm1) ENSG00000081087(OSTM1) viable FBgn0067657 sd-10 sd-10 http://flybase.net/reports/FBgn0067657.html gene "0007270=neuron-neuron synaptic transmission, 0042331=phototaxis" complementation group 10 16-Dec-15 2015_12 "neurophysiology defective,somatic clone,lethal,recessive,phototaxis defective" FBgn0053796 CG33796 http://flybase.net/reports/FBgn0053796.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33796 16-Dec-15 2015_12 FBgn0002225 l(3)68Ae lethal (3) 68Ae http://flybase.net/reports/FBgn0002225.html FBgn0002226 gene "Complementation group J, l(3)J, l(3)68Ae', l(3)C206, J" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051890 tRNA:CR31890 transfer RNA:CR31890 http://flybase.net/reports/FBgn0051890.html "FBgn0011843, FBgn0060261" tRNA_gene "0033458=GAC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2L.trna17-AspGTC, tRNA:D2:29E, CR31890, tRNA:asp2:29E, tRNA[[Asp]], transfer RNA:asp2:29E, tRNA[Asp-GTC], AE002690.trna8-AspGTC, tRNA:D:GTC:AE002690-d" CR31890 16-Dec-15 2015_12 FBgn0267035 CR45479 http://flybase.net/reports/FBgn0267035.html non_protein_coding_gene CR45479 16-Dec-15 2015_12 FBgn0050354 UQCR-11L Ubiquinol-cytochrome c reductase 11 kDa subunit-like http://flybase.net/reports/FBgn0050354.html FBgn0045437 protein_coding_gene 0008121=ubiquinol-cytochrome-c reductase activity "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" 0005750=mitochondrial respiratory chain complex III "UCRH, NEST:bs01g03, CG30354, Ubiquinol-cytochrome C reductase complex 11 kDa protein, Ubiquinol-cytochrome c reductase 11 kDa protein" "IPR003422=Cytochrome b-c1 complex, subunit 6, IPR023184=Ubiquinol-cytochrome C reductase hinge domain" CG30354 16-Dec-15 2015_12 ENSDARG00000059128 WBGene00012094(T27E9.2) ENSXETG00000004366(UQCRH) ENSMUSG00000063882(Uqcrh) ENSG00000173660(UQCRH) viable FBgn0011181 l(1)291-100 lethal (1) 291-100 http://flybase.net/reports/FBgn0011181.html FBgn0010199 gene 291-100 16-Dec-15 2015_12 "lethal,recessive" FBgn0004220 l(3)84Fh lethal (3) 84Fh http://flybase.net/reports/FBgn0004220.html gene 16-Dec-15 2015_12 lethal FBgn0263001 CR43309 http://flybase.net/reports/FBgn0263001.html non_protein_coding_gene lincRNA.648 CR43309 16-Dec-15 2015_12 FBgn0262559 Mdh2 Malate dehydrogenase 2 http://flybase.net/reports/FBgn0262559.html "FBgn0002700, FBgn0038587" protein_coding_gene "0030060=L-malate dehydrogenase activity, 0016615=malate dehydrogenase activity" "0035070=salivary gland histolysis, 0005975=carbohydrate metabolic process, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0006099=tricarboxylic acid cycle, 0006108=malate metabolic process, 0035071=salivary gland cell autophagic cell death, 0035096=larval midgut cell programmed cell death, 0043068=positive regulation of programmed cell death, 0035209=pupal development, 0043067=regulation of programmed cell death" "0005811=lipid particle, 0005739=mitochondrion, 0005759=mitochondrial matrix" "MDH-2, L-Malate dehydrogenase, psg7, Malate dehydrogenase, Mdh, CG 7998, malate dehydrogenase, CG7998, mMdh, mitochondrial malate dehydrogenase, lethal (3) persistent salivary gland 7, mitochondrial-Mdh, Malic DH, l(3)psg7, mdh2" "IPR010097=Malate dehydrogenase, type 1, IPR016040=NAD(P)-binding domain, IPR001557=L-lactate/malate dehydrogenase, IPR022383=Lactate/malate dehydrogenase, C-terminal, IPR015955=Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR001236=Lactate/malate dehydrogenase, N-terminal" CG7998 16-Dec-15 2015_12 ENSDARG00000043371 YKL085W(MDH1) WBGene00003162(mdh-1) ENSXETG00000008976(mdh2) ENSMUSG00000019179(Mdh2) ENSG00000146701(MDH2) FBgn0039521 CG5402 http://flybase.net/reports/FBgn0039521.html FBgn0044539 protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space anon-WO0140519.87 CG5402 16-Dec-15 2015_12 viable FBgn0060941 l(3)S039606b lethal (3) S039606b http://flybase.net/reports/FBgn0060941.html gene 0396/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0267559 CR45899 http://flybase.net/reports/FBgn0267559.html non_protein_coding_gene lincRNA.701 CR45899 16-Dec-15 2015_12 FBgn0011725 twin twin http://flybase.net/reports/FBgn0011725.html "FBgn0039166, FBgn0039168, FBgn0045815, FBgn0051137" protein_coding_gene 0005515=protein binding "0006357=regulation of transcription from RNA polymerase II promoter, 0006402=mRNA catabolic process, 0000288=nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, 0048477=oogenesis, 0048132=female germ-line stem cell asymmetric division, 0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0017148=negative regulation of translation" "0005737=cytoplasm, 0005829=cytosol, 0030014=CCR4-NOT complex" "CT39331, Ccr4, twn, CG5534, ccr4, Twin, CG31137, CG17741, BEST:GH20274, CCR4" "IPR001611=Leucine-rich repeat, IPR005135=Endonuclease/exonuclease/phosphatase, IPR003591=Leucine-rich repeat, typical subtype" CG31137 16-Dec-15 2015_12 "ENSDARG00000008255(cnot6),ENSDARG00000022001(zgc:171797),ENSDARG00000054597(cnot6l)" YAL021C(CCR4) WBGene00000376(ccr-4) ENSXETG00000000372(CNOT6L) "ENSMUSG00000034724(Cnot6l),ENSMUSG00000020362(Cnot6)" "ENSG00000138767(CNOT6L),ENSG00000113300(CNOT6)" "viable,female sterile,male fertile,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,fertile,neuroanatomy defective" "egg chamber,nurse cell ring canal,supernumerary,oocyte,female germline stem cell,cell autonomous,germline clone,nurse cell,syncytial blastoderm embryo,maternal effect,embryonic head,embryonic/larval neuromuscular junction,type Ib terminal bouton | supernumerary | third instar larval stage" FBgn0003101 PL(2)sp-G2 Polygenic locus sternopleural G2 http://flybase.net/reports/FBgn0003101.html gene PL(2)sp[G2] 16-Dec-15 2015_12 FBgn0028896 CG17329 http://flybase.net/reports/FBgn0028896.html FBgn0063724 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0005634=nucleus "DS02740.5, BcDNA:AT18988, BG:DS02740.5" "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG17329 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0260437 CR42532 http://flybase.net/reports/FBgn0260437.html pseudogene_attribute CR42532 16-Dec-15 2015_12 FBgn0043892 l(1)U93 lethal (1) U93 http://flybase.net/reports/FBgn0043892.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/first instar larval cuticle,salivary gland" FBgn0005599 yemG3b yema gene 3b http://flybase.net/reports/FBgn0005599.html FBgn0004042 gene "yT3b, unnamed, yG3b" 16-Dec-15 2015_12 " larval stage--adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage--pupal stage , embryonic stage | 12-18 hr , embryonic stage | embryonic stage <=8 " " spermatocyte

, ovary

, central nervous system | restricted

, imaginal disc

, hindgut

, organism

" FBgn0022289 l(2)05559b lethal (2) 05559b http://flybase.net/reports/FBgn0022289.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0069310 X-28-2 X-28-2 http://flybase.net/reports/FBgn0069310.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal,germline clone,recessive,rescuable maternal effect" FBgn0262123 l(2)41Ab lethal (2) 41Ab http://flybase.net/reports/FBgn0262123.html "FBgn0002064, FBan0041265, FBgn0085586, FBgn0058214, FBgn0058334" protein_coding_gene "0003341=cilium movement, 0070286=axonemal dynein complex assembly" 0005737=cytoplasm "1(2R)B, l(2)EMS45-10, l(2R)B, 41Ab, CG40214, CG40334, CG41265, GroupI" CG41265 16-Dec-15 2015_12 ENSDARG00000016813 ENSXETG00000004200() ENSMUSG00000039963(Ccdc40) ENSG00000141519(CCDC40) FBgn0067312 CheB38a Chemosensory protein B 38a http://flybase.net/reports/FBgn0067312.html "FBgn0032887, FBgn0053320" protein_coding_gene 0008289=lipid binding "0007606=sensory perception of chemical stimulus, 0043695=detection of pheromone" "0005615=extracellular space, 0005576=extracellular region" "38E.23, CheB38a, CG9329, CG33320" "IPR006601=Uncharacterised protein family DM11, Drosophila melanogaster" CG33320 16-Dec-15 2015_12 DRSC03205 I -0.290018803 -1.575845456 -0.474739078 -0.083109136 -0.602848841 -0.684576244 FBgn0267153 CR45593 http://flybase.net/reports/FBgn0267153.html non_protein_coding_gene CR45593 16-Dec-15 2015_12 FBgn0026060 Mipp2 Multiple inositol polyphosphate phosphatase 2 http://flybase.net/reports/FBgn0026060.html "FBgn0026701, FBgn0029065" protein_coding_gene "0003993=acid phosphatase activity, 0034417=bisphosphoglycerate 3-phosphatase activity" "0016311=dephosphorylation, 0031929=TOR signaling" "0031931=TORC1 complex, 0070062=extracellular exosome" "l(1)G0050, l(1)G0303, CG4317" "IPR029033=Histidine phosphatase superfamily, IPR004083=Regulatory associated protein of TOR, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR000560=Histidine phosphatase superfamily, clade-2, IPR015943=WD40/YVTN repeat-like-containing domain, IPR016274=Histidine acid phosphatase, eukaryotic" CG4317 16-Dec-15 2015_12 ENSDARG00000045172(minpp1b) ENSXETG00000006618(MINPP1) ENSMUSG00000024896(Minpp1) ENSG00000107789(MINPP1) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" "third instar larva,synapse,neuromuscular junction" FBgn0005277 M(1)k Minute (1) k http://flybase.net/reports/FBgn0005277.html gene Minute 1(k) 16-Dec-15 2015_12 FBgn0040397 CG3655 http://flybase.net/reports/FBgn0040397.html FBgn0029557 protein_coding_gene "RE126B2, EG:103E12.3" IPR008166=Glycosyltransferase family 92 CG3655 16-Dec-15 2015_12 ENSDARG00000053345(LOC100334791) WBGene00012941(Y47D3B.4) "ENSXETG00000026707(),ENSXETG00000026391()" "viable,fertile" FBgn0030086 CG7033 http://flybase.net/reports/FBgn0030086.html protein_coding_gene "0051082=unfolded protein binding, 0005524=ATP binding" "0051298=centrosome duplication, 0031122=cytoplasmic microtubule organization, 0022008=neurogenesis, 0006457=protein folding, 0090307=mitotic spindle assembly, 0007052=mitotic spindle organization" "0005875=microtubule associated complex, 0072686=mitotic spindle, 0005811=lipid particle, 0005832=chaperonin-containing T-complex, 0005737=cytoplasm" "TCP-1 Subunit 2beta, Tcp1-beta, SD02216p, TCP-1beta, Q8IRM8_DROME, Cct2, Q9W392_DROME, TCP1beta, CCT2" "IPR002194=Chaperonin TCP-1, conserved site, IPR012716=T-complex protein 1, beta subunit, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR027410=TCP-1-like chaperonin intermediate domain, IPR017998=Chaperone tailless complex polypeptide 1 (TCP-1), IPR027413=GroEL-like equatorial domain, IPR027409=GroEL-like apical domain" CG7033 16-Dec-15 2015_12 ENSDARG00000041754 YIL142W(CCT2) WBGene00000378(cct-2) ENSXETG00000001410(cct2) ENSMUSG00000034024(Cct2) ENSG00000166226(CCT2) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,neuroblast | larval stage" DRSC18415 E 0.182125564 -1.116146489 0.10599678 -2.029641783 -0.263740098 0.134988671 FBgn0030555 Fbxl4 F box and leucine-rich-repeat gene 4 http://flybase.net/reports/FBgn0030555.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0016059=deactivation of rhodopsin mediated signaling, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process" 0019005=SCF ubiquitin ligase complex "dFbxl4, CG1839, FBXL4" IPR001810=F-box domain CG1839 16-Dec-15 2015_12 ENSDARG00000026941(fbxl4) ENSXETG00000001389(FBXL4) ENSMUSG00000040410(Fbxl4) ENSG00000112234(FBXL4) "viable,fertile" FBgn0041613 X-element\ORF1 ORF1 http://flybase.net/reports/FBgn0041613.html transposable_element_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "0006313=transposition, DNA-mediated" "IPR001878=Zinc finger, CCHC-type, IPR006579=Pre-C2HC domain" 16-Dec-15 2015_12 FBgn0262369 mir-31b mir-31b stem loop http://flybase.net/reports/FBgn0262369.html "FBgn0067684, FBgn0262175" miRNA_gene "0035282=segmentation, 0046716=muscle cell cellular homeostasis" "miR-31b, mir-31b, miR-31, dme-miR-31b, CR42882, CR33568, dme-mir-31b" CR42882 16-Dec-15 2015_12 "viable,visible,lethal" "wing,wing margin bristle,wing vein L5,wing margin" FBgn0034968 RpL12 Ribosomal protein L12 http://flybase.net/reports/FBgn0034968.html FBgn0002611 protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "Q9W1B9_DROME, anon-EST:Posey236, L12, CG3195, Rpl12, RPL12, Rp L12" "IPR020784=Ribosomal protein L11, N-terminal, IPR020783=Ribosomal protein L11, C-terminal, IPR000911=Ribosomal protein L11/L12, IPR020785=Ribosomal protein L11, conserved site" CG3195 16-Dec-15 2015_12 ENSDARG00000006691(rpl12) "YEL054C(RPL12A),YDR418W(RPL12B)" WBGene00004424(rpl-12) ENSXETG00000003944(rpl12) "ENSMUSG00000063328(Gm9396),ENSMUSG00000069682(Gm10275),ENSMUSG00000080054(Rpl12-ps1),ENSMUSG00000066983(Gm16519)" ENSG00000197958(RPL12) "lethal,viable,developmental rate defective" DRSC04344 IE -2.554521324 -2.286701748 1.784145929 -4.843007321 0.689624812 1.196897334 FBgn0266717 Bruce BIR repeat containing ubiquitin-conjugating enzyme http://flybase.net/reports/FBgn0266717.html "FBgn0037808, FBgn0041108" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0061631=ubiquitin conjugating enzyme activity" "0032465=regulation of cytokinesis, 0009267=cellular response to starvation, 0045849=negative regulation of nurse cell apoptotic process, 0048477=oogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0012501=programmed cell death, 0043066=negative regulation of apoptotic process, 0000209=protein polyubiquitination, 0007286=spermatid development, 0016242=negative regulation of macroautophagy, 0007291=sperm individualization" "CG6303, dBruce, Bruce, mod86, BRUCE, dBRUCE, bruce, dbruce" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR001370=BIR repeat, IPR000608=Ubiquitin-conjugating enzyme E2, IPR022103=Baculoviral IAP repeat-containing protein 6, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG6303 16-Dec-15 2015_12 ENSXETG00000017697(BIRC6) ENSMUSG00000024073(Birc6) ENSG00000115760(BIRC6) FBgn0002885 mus111 mutagen-sensitive 111 http://flybase.net/reports/FBgn0002885.html gene mus(1)111 16-Dec-15 2015_12 "radiation sensitive,chemical sensitive,female sterile,recessive" FBgn0260780 wisp wispy http://flybase.net/reports/FBgn0260780.html "FBgn0024180, FBgn0000835, FBgn0030353" protein_coding_gene 0004652=polynucleotide adenylyltransferase activity "0007056=spindle assembly involved in female meiosis, 0007344=pronuclear fusion, 0002805=regulation of antimicrobial peptide biosynthetic process, 0008298=intracellular mRNA localization, 0035046=pronuclear migration, 0007343=egg activation, 0007052=mitotic spindle organization, 0006378=mRNA polyadenylation, 0043631=RNA polyadenylation, 0001556=oocyte maturation, 0035044=sperm aster formation, 0007017=microtubule-based process" "Toll pathway activation mediating protein, DmCG15737, wispy, female sterile(1)M19, WISPY, Wisp, TAMP, fs(1)M19, temprano, CG15737" IPR002058=PAP/25A-associated CG15737 16-Dec-15 2015_12 "ENSDARG00000055385(LOC100333585),ENSDARG00000071511(papd4)" "YOL115W(PAP2),YNL299W(TRF5)" WBGene00001596(gld-2) ENSMUSG00000042167(Papd4) ENSG00000164329(PAPD4) FBgn0013470 l(1)10P11 lethal (1) 10P11 http://flybase.net/reports/FBgn0013470.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" "egg,germline clone,segment" FBgn0005703 l(1)TK106 lethal (1) TK106 http://flybase.net/reports/FBgn0005703.html gene l106 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0025927 l(1)43 lethal (1) 43 http://flybase.net/reports/FBgn0025927.html gene "l-43, lethal-43" 16-Dec-15 2015_12 "lethal,recessive" FBgn0024757 EC88 EC88 http://flybase.net/reports/FBgn0024757.html gene 16-Dec-15 2015_12 "enhancer of variegation,female,non-enhancer of variegation,male" FBgn0051204 CG31204 http://flybase.net/reports/FBgn0051204.html "FBgn0039845, FBgn0064998" protein_coding_gene "CG15569, BcDNA:AT25127" CG31204 16-Dec-15 2015_12 viable FBgn0083296 E(smoDN)1875 Enhancer of smoDN 1875 http://flybase.net/reports/FBgn0083296.html gene 16-Dec-15 2015_12 FBgn0067369 l(2)NC192 lethal (2) NC192 http://flybase.net/reports/FBgn0067369.html gene NC192 16-Dec-15 2015_12 "lethal,recessive" FBgn0011884 tRNA:I:49Fd transfer RNA:ile:49Fd http://flybase.net/reports/FBgn0011884.html "FBgn0003788, FBgn0050246, FBgn0060197" tRNA_gene "0033433=AUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "ile-d, tRNA[Ile], tRNA:I:AAT:AE002787-e, chr2R.trna21-IleAAT, tRNA:ile:49Fd, AE002787.trna39-IleAAT, CR30246" CR30246 16-Dec-15 2015_12 FBgn0036952 CG6933 http://flybase.net/reports/FBgn0036952.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region IPR002557=Chitin binding domain CG6933 16-Dec-15 2015_12 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0086063 snoRNA:Me28S-C788a http://flybase.net/reports/FBgn0086063.html snoRNA_gene "CR34692, DmSnR58a, Me28S-C788a(DmSnR58), Me28S-Cm788a" CR34692 16-Dec-15 2015_12 FBgn0065318 l(2)SH1923 lethal (2) SH1923 http://flybase.net/reports/FBgn0065318.html gene l(2)SH2 1923 16-Dec-15 2015_12 "lethal,recessive" FBgn0052259 CG32259 http://flybase.net/reports/FBgn0052259.html FBgn0045168 protein_coding_gene NEST:bs27e11 CG32259 16-Dec-15 2015_12 viable FBgn0266764 CR45229 http://flybase.net/reports/FBgn0266764.html non_protein_coding_gene CR45229 16-Dec-15 2015_12 FBgn0010027 E(Dl)F167 Enhancer of Delta F167 http://flybase.net/reports/FBgn0010027.html gene 16-Dec-15 2015_12 FBgn0028222 l(3)S007403a lethal (3) S007403a http://flybase.net/reports/FBgn0028222.html gene "l(3)s007403, l(3)S007403, 0074/03" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030116 CR17438 http://flybase.net/reports/FBgn0030116.html pseudogene_attribute CG17438 CR17438 16-Dec-15 2015_12 FBgn0266731 CR45204 http://flybase.net/reports/FBgn0266731.html non_protein_coding_gene CR45204 16-Dec-15 2015_12 FBgn0016802 l(1)K4 lethal (1) K4 http://flybase.net/reports/FBgn0016802.html gene K4 16-Dec-15 2015_12 "lethal,recessive" FBgn0263502 CR43491 http://flybase.net/reports/FBgn0263502.html non_protein_coding_gene CR43491 16-Dec-15 2015_12 FBgn0265845 CR44634 http://flybase.net/reports/FBgn0265845.html non_protein_coding_gene CR44634 16-Dec-15 2015_12 FBgn0011819 Orf5C Orf5C http://flybase.net/reports/FBgn0011819.html gene "anon-5C, unnamed, X-peptide" 16-Dec-15 2015_12 FBgn0266132 c65 http://flybase.net/reports/FBgn0266132.html gene 0042332=gravitaxis 16-Dec-15 2015_12 gravitaxis defective FBgn0035251 CG7967 http://flybase.net/reports/FBgn0035251.html protein_coding_gene 0001671=ATPase activator activity 0032509=endosome transport via multivesicular body sorting pathway "0005771=multivesicular body, 1990621=Vps4-Vta1 complex" "IPR023175=Vacuolar protein sorting-associate protein Vta1/Callose synthase, N-terminal domain" CG7967 16-Dec-15 2015_12 ENSDARG00000013732(vta1) YLR181C(VTA1) ENSXETG00000021109(TGas087d17.1) ENSMUSG00000019868(Vta1) ENSG00000009844(VTA1) FBgn0035688 CG10289 http://flybase.net/reports/FBgn0035688.html protein_coding_gene PpV[[R]] IPR007587=SIT4 phosphatase-associated protein family CG10289 16-Dec-15 2015_12 "ENSDARG00000013379(saps3),ENSDARG00000045540(ppp6r2),ENSDARG00000069654" "YJL098W(SAP185),YKR028W(SAP190),YFR040W(SAP155),YGL229C(SAP4)" WBGene00008166(saps-1) "ENSXETG00000023068(SAPS2),ENSXETG00000002985(SAPS3),ENSXETG00000022927(SAPS1)" "ENSMUSG00000036561(Ppp6r2),ENSMUSG00000024908(Ppp6r3),ENSMUSG00000052296(Ppp6r1)" "ENSG00000110075(PPP6R3),ENSG00000100239(PPP6R2),ENSG00000105063(PPP6R1)" "partially lethal - majority die,some die during pupal stage" FBgn0013279 Hsp70Bc Heat-shock-protein-70Bc http://flybase.net/reports/FBgn0013279.html "FBgn0001232, FBgn0038059" protein_coding_gene "0009408=response to heat, 0031427=response to methotrexate, 0035080=heat shock-mediated polytene chromosome puffing, 0001666=response to hypoxia" 0005875=microtubule associated complex "hsp-70, dHsp70, Hsp 70, 87C locus, Hsp70A7d, Dm-hsp70, Hsp70, heat-shock-protein 70bc, CG6489, Hsp70Bbc, Hsp70-BC, hsp70B, heat-shock protein 70, Protein 70, Hsp-70, hsp70, Hsp70B, dhsp70, Hsp70Bd, hsp70Bc, Hsp-70Bc, HSP70, hsp70 87C, Hsp70(87C), HSP70Bc, heat shock 70, heat shock protein 70, Bc" "IPR013126=Heat shock protein 70 family, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site" CG6489 16-Dec-15 2015_12 "aging defective,male limited,heat sensitive" DRSC16053 E -0.484495433 -1.336312072 -4.955363662 -2.221734912 0.00255059 0.957092036 FBgn0005078 fs(2)OW802 female sterile (2) OW802 http://flybase.net/reports/FBgn0005078.html gene 16-Dec-15 2015_12 FBgn0040272 Su(Rex) Su(Rex) http://flybase.net/reports/FBgn0040272.html gene 16-Dec-15 2015_12 FBgn0267684 CR46020 http://flybase.net/reports/FBgn0267684.html non_protein_coding_gene CR46020 16-Dec-15 2015_12 FBgn0065143 l(3)SH094 lethal (3) SH094 http://flybase.net/reports/FBgn0065143.html gene l(2)SH3 094 16-Dec-15 2015_12 "lethal,recessive" FBgn0086078 snoRNA:Me28S-A774b http://flybase.net/reports/FBgn0086078.html snoRNA_gene "DmU18b, Me28S-Am774b, CR34707" CR34707 16-Dec-15 2015_12 FBgn0259444 EP-36 http://flybase.net/reports/FBgn0259444.html gene 16-Dec-15 2015_12 visible "wing vein,wing" FBgn0033010 Atf6 Atf6 http://flybase.net/reports/FBgn0033010.html FBan0003136 protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0042803=protein homodimerization activity" "0006355=regulation of transcription, DNA-templated" "atf6, DM15, CG3136, ATF6" IPR004827=Basic-leucine zipper domain CG3136 16-Dec-15 2015_12 ENSDARG00000012656(si:ch211-199m3.9) ENSXETG00000005164() "ENSMUSG00000026663(Atf6),ENSMUSG00000015461(Atf6b)" "ENSG00000118217(ATF6),ENSG00000168468,ENSG00000213676(ATF6B)" "viable,fertile" DRSC19797 I 1.943321295 0.336647229 -0.058478207 0.345330912 -0.260409425 -0.10536524 FBgn0001923 l(2)25Cd lethal (2) 25Cd http://flybase.net/reports/FBgn0001923.html gene "l(2)jf18, jf18" 16-Dec-15 2015_12 lethal FBgn0011576 Cyp4d2 Cytochrome P450-4d2 http://flybase.net/reports/FBgn0011576.html "FBgn0010219, FBgn0010384" protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "Cyt-P450-4D2, Cyp4D2, cytochrome P-450, P450, Cytochrome P450 4D2, 4d2, CG3466, P-450, EG:152A3.4, CYP4D2, cytochrome P450" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG3466 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0033742 CG8550 http://flybase.net/reports/FBgn0033742.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR018497=Peptidase M13, C-terminal domain" CG8550 16-Dec-15 2015_12 "fertile,viable" FBgn0038814 CG15923 http://flybase.net/reports/FBgn0038814.html protein_coding_gene "0051726=regulation of cell cycle, 0010826=negative regulation of centrosome duplication, 0042384=cilium assembly" 0036038=TCTN-B9D complex IPR019170=Meckelin CG15923 16-Dec-15 2015_12 WBGene00018042(F35D2.4) "ENSXETG00000014689(TMEM67),ENSXETG00000017418()" ENSMUSG00000049488(Tmem67) ENSG00000164953(TMEM67) partially lethal - majority die FBgn0051950 CG31950 http://flybase.net/reports/FBgn0051950.html protein_coding_gene 0030532=small nuclear ribonucleoprotein complex "IPR001163=LSM domain, eukaryotic/archaea-type, IPR010920=LSM domain" CG31950 16-Dec-15 2015_12 ENSDARG00000067677(lsmd1) ENSXETG00000015633(LSMD1) ENSMUSG00000059278(Lsmd1) viable DRSC00160 I 1.576241843 -0.194312383 0.031320643 -0.919928899 -0.698711682 -1.256418018 FBgn0022737 en::sr en::sr http://flybase.net/reports/FBgn0022737.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 "embryonic/larval somatic muscle,muscle fiber | embryonic stage,ventral oblique muscle | embryonic stage" FBgn0065292 l(2)SH2004 lethal (2) SH2004 http://flybase.net/reports/FBgn0065292.html gene l(2)SH2 2004 16-Dec-15 2015_12 "lethal,recessive" FBgn0260079 2L4508 http://flybase.net/reports/FBgn0260079.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0022328 l(1)A13.3 lethal (1) A13.3 http://flybase.net/reports/FBgn0022328.html gene A13.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0001546 l(1)15Ba lethal (1) 15Ba http://flybase.net/reports/FBgn0001546.html gene l(1)g27a 16-Dec-15 2015_12 "lethal,recessive" FBgn0085415 CG34386 http://flybase.net/reports/FBgn0085415.html "FBgn0034297, FBgn0034298" protein_coding_gene "CG14496, CG14497" CG34386 16-Dec-15 2015_12 WBGene00010449(K01A11.1) "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0035563 CG13716 http://flybase.net/reports/FBgn0035563.html protein_coding_gene 0032879=regulation of localization HL1 IPR007970=Protein of unknown function DUF733 CG13716 16-Dec-15 2015_12 viable FBgn0005163 l(2)G341 lethal (2) G341 http://flybase.net/reports/FBgn0005163.html gene 16-Dec-15 2015_12 lethal FBgn0264370 CR43822 http://flybase.net/reports/FBgn0264370.html non_protein_coding_gene CR43822 16-Dec-15 2015_12 FBgn0002547 lfl little fly-like http://flybase.net/reports/FBgn0002547.html FBgn0011265 gene "l(1)19Fa, 11, section 10, 10, B-56, l(1)B56, J22, section 11, Little fly like, l(1)HM46, section 13, 13, B-96" 16-Dec-15 2015_12 "lethal,recessive,male,visible,cell lethal,germline clone,viable,reduced,lethal - all die before end of larval stage,some die during larval stage" "adult thorax & microchaeta,adult thorax & macrochaeta,head bristle,eye,wing,posterior crossvein,ocellar bristle,postvertical bristle,humeral bristle" FBgn0051898 CG31898 http://flybase.net/reports/FBgn0051898.html FBgn0047203 protein_coding_gene BcDNA:LD28680 CG31898 16-Dec-15 2015_12 "viable,fertile" FBgn0264742 CG44000 http://flybase.net/reports/FBgn0264742.html FBgn0031674 protein_coding_gene "CG31919, CG5822, Dromel_CG31919_FBtr0079006_mORF" CG44000 16-Dec-15 2015_12 FBgn0021954 l(2)k10239 lethal (2) k10239 http://flybase.net/reports/FBgn0021954.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0025626 CG4281 http://flybase.net/reports/FBgn0025626.html protein_coding_gene EG:22E5.7 IPR026291=G patch domain-containing protein 2 CG4281 16-Dec-15 2015_12 "lethal,recessive,viable,visible" trichogen cell FBgn0053772 CG33772 http://flybase.net/reports/FBgn0053772.html FBgn0082875 protein_coding_gene "unnamed, BP1031" IPR010512=Protein of unknown function DUF1091 CG33772 16-Dec-15 2015_12 viable FBgn0036959 CG6951 http://flybase.net/reports/FBgn0036959.html FBgn0061863 protein_coding_gene "0008270=zinc ion binding, 0004132=dCMP deaminase activity" anon-WO0118547.579 "IPR015517=Deoxycytidylate deaminase-related, IPR016192=APOBEC/CMP deaminase, zinc-binding, IPR016193=Cytidine deaminase-like, IPR002125=Cytidine and deoxycytidylate deaminases, zinc-binding" CG6951 16-Dec-15 2015_12 ENSDARG00000036990(dctd) WBGene00014034(ZK643.2) ENSXETG00000019042(dctd) ENSMUSG00000031562(Dctd) ENSG00000129187(DCTD) viable FBgn0024763 EC33 EC33 http://flybase.net/reports/FBgn0024763.html gene 16-Dec-15 2015_12 "enhancer of variegation,non-enhancer of variegation" FBgn0032957 CG2225 http://flybase.net/reports/FBgn0032957.html protein_coding_gene CG2225 16-Dec-15 2015_12 "viable,fertile" FBgn0005491 l(1)ts2641 lethal (1) ts2641 http://flybase.net/reports/FBgn0005491.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,female sterile" FBgn0010294 ng2 new glue 2 http://flybase.net/reports/FBgn0010294.html FBgn0063074 protein_coding_gene 0005198=structural molecule activity 0007594=puparial adhesion 0005576=extracellular region "BcDNA:RE05239, CG14266, EG:96G10.4, ng, ng-2" CG14266 16-Dec-15 2015_12 FBgn0005602 yemG3c yema gene 3c http://flybase.net/reports/FBgn0005602.html FBgn0004042 gene "yT0.7, yG0.7, yG3c/0.7, yG3c, unnamed, yT3c" 16-Dec-15 2015_12 " larval stage--adult stage , adult stage && oogenesis stage , embryonic stage | stage <= 8 , embryonic stage , embryonic stage | 12-18 hr , embryonic stage | stage <=8 , embryonic stage--larval stage , embryonic stage -- adult stage , larval stage--pupal stage , larval stage , pupal stage " " spermatocyte

, ovary

, organism

, lymph gland | restricted

, central nervous system | restricted

, imaginal disc

, hindgut

" FBgn0260655 l(3)76BDm lethal (3) 76BDm http://flybase.net/reports/FBgn0260655.html "FBgn0036894, FBgn0084349, FBgn0024548" protein_coding_gene 0006888=ER to Golgi vesicle-mediated transport 0030008=TRAPP complex "lethal (3) L3809, l(3)76BDm, CG8793, l(3)L3809" "IPR024420=TRAPP III complex, Trs85, IPR011990=Tetratricopeptide-like helical domain, IPR013935=TRAPP II complex, Trs120" CG8793 16-Dec-15 2015_12 WBGene00018512(F46F11.9) ENSXETG00000004734(KIAA1012) ENSMUSG00000033382(D030074E01Rik) ENSG00000153339(TRAPPC8) FBgn0263383 CR43435 http://flybase.net/reports/FBgn0263383.html non_protein_coding_gene CR43435 16-Dec-15 2015_12 FBgn0010844 l(3)04629 lethal (3) 04629 http://flybase.net/reports/FBgn0010844.html gene "6/24, 0006/24" 16-Dec-15 2015_12 "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0060656 l(3)S082901 lethal (3) S082901 http://flybase.net/reports/FBgn0060656.html gene 0829/01 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0010424 TpnC73F Troponin C at 73F http://flybase.net/reports/FBgn0010424.html protein_coding_gene 0005509=calcium ion binding "TnC73F, DmTnC3, unnamed, DmTpnC73F, tpnC73F, CG7930, TNC73F, DmTpnCIa, TpnCIa, troponin C, TpnC Ia, TroponinC73F, TNC, TnC, troponin C73F" "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG7930 16-Dec-15 2015_12 WBGene00006583(tnc-2) " larval stage , pupal stage , embryonic stage | late , embryonic stage -- adult stage " organism

"lethal,viable" FBgn0259365 C327.2 http://flybase.net/reports/FBgn0259365.html gene 16-Dec-15 2015_12 visible "wing vein,wing margin" FBgn0027561 CG18659 http://flybase.net/reports/FBgn0027561.html "FBgn0042194, FBgn0050347, FBgn0050348, FBgn0062216, FBgn0062219" protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0006897=endocytosis, 0032483=regulation of Rab protein signal transduction" 0030136=clathrin-coated vesicle "anon-WO0118547.140, CG8059, anon-WO0118547.145, BcDNA:GH08789, CG30347, CG30348" "IPR005113=uDENN domain, IPR005112=dDENN domain, IPR001194=DENN domain" CG18659 16-Dec-15 2015_12 ENSDARG00000014592(dennd1a) WBGene00004375(rme-4) "ENSMUSG00000035392(Dennd1a),ENSMUSG00000056268(Dennd1b),ENSMUSG00000002668(Dennd1c)" FBgn0034416 CG15109 http://flybase.net/reports/FBgn0034416.html protein_coding_gene CG15109 16-Dec-15 2015_12 viable FBgn0039257 tnc tenectin http://flybase.net/reports/FBgn0039257.html protein_coding_gene "0005201=extracellular matrix structural constituent, 0005178=integrin binding" "0007472=wing disc morphogenesis, 0035296=regulation of tube diameter, 0060562=epithelial tube morphogenesis, 0048803=imaginal disc-derived male genitalia morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0048619=embryonic hindgut morphogenesis" "0031012=extracellular matrix, 0005615=extracellular space" "Tenectin, Mucin related 96B, Tnc, CG13648, Mur96B" IPR001007=VWFC domain CG13648 16-Dec-15 2015_12 "viable,lethal,visible" "embryonic/larval hindgut,embryonic large intestine,embryonic small intestine,embryonic/larval dorsal trunk,male genitalia,wing,wing margin,embryonic/larval salivary gland,embryonic Malpighian tubule,primary trachea,mesothoracic tergum" FBgn0069093 p170 p170 http://flybase.net/reports/FBgn0069093.html gene 16-Dec-15 2015_12 FBgn0267106 CG45546 http://flybase.net/reports/FBgn0267106.html protein_coding_gene "IPR002919=Trypsin Inhibitor-like, cysteine rich domain" CG45546 16-Dec-15 2015_12 FBgn0027166 l(2)K2 lethal (2) K2 http://flybase.net/reports/FBgn0027166.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0041156 exex extra-extra http://flybase.net/reports/FBgn0041156.html FBgn0035828 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0007417=central nervous system development, 0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0046331=lateral inhibition, 0061101=neuroendocrine cell differentiation, 0007412=axon target recognition" 0005634=nucleus "CG8254, hb9, dHb9, HB9, dhb9, DHB9, Hb9, Extra-extra" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa" CG8254 16-Dec-15 2015_12 WBGene00000584(cog-1) ENSXETG00000005051(MEOX2) ENSG00000130675(MNX1) "neuroanatomy defective,viable,visible" "intersegmental nerve branch ISNb of A1-7,transverse nerve,embryonic ventral nervous system & neuron,intersegmental nerve,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,axon | embryonic stage,growth cone | embryonic stage,EW1 neuron,EW2 neuron,EW3 neuron,neuromuscular junction | embryonic stage,neuron,lateral,presumptive embryonic/larval central nervous system,abdominal segmental nerve | embryonic stage,intersegmental nerve | embryonic stage,longitudinal connective | embryonic stage,chaeta,supernumerary" FBgn0262755 Mst77Y-6ë¬ Male-specific pseudogene 77Y 6 http://flybase.net/reports/FBgn0262755.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0011649 Mads-1 Mads-1 http://flybase.net/reports/FBgn0011649.html gene 16-Dec-15 2015_12 FBgn0266406 CR45046 http://flybase.net/reports/FBgn0266406.html non_protein_coding_gene CR45046 16-Dec-15 2015_12 FBgn0014100 anon-44DE anon-44DE http://flybase.net/reports/FBgn0014100.html gene 16-Dec-15 2015_12 FBgn0001938 l(2)25Fd lethal (2) 25Fd http://flybase.net/reports/FBgn0001938.html gene l(2)gdh-16 16-Dec-15 2015_12 "lethal,recessive" FBgn0044379 anon-AE003450.1 anon-AE003450.1 http://flybase.net/reports/FBgn0044379.html gene 16-Dec-15 2015_12 FBgn0033192 Corin Corin http://flybase.net/reports/FBgn0033192.html protein_coding_gene "0005044=scavenger receptor activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis 0016020=membrane "DCorin, SP75, CG2105" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001190=SRCR domain, IPR020067=Frizzled domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR017448=SRCR-like domain" CG2105 16-Dec-15 2015_12 ENSMUSG00000037129(Tmprss13) ENSG00000137747(TMPRSS13) viable DRSC06818 IE 1.596393932 -0.11992282 -0.121184606 2.284410419 0.285736736 -0.015319946 FBgn0020588 anon-57Ci anon-57Ci http://flybase.net/reports/FBgn0020588.html gene unnamed 16-Dec-15 2015_12 FBgn0011310 l(3)j1B9 lethal (3) j1B9 http://flybase.net/reports/FBgn0011310.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022186 l(2)k05204 lethal (2) k05204 http://flybase.net/reports/FBgn0022186.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0250732 gfzf GST-containing FLYWCH zinc-finger protein http://flybase.net/reports/FBgn0250732.html "FBpp0081126, FBtr0081608, FBpp0081125, FBtr0081607, FBgn0051492, FBgn0051329, FBgn0037479, FBgn0053546, FBgn0002305" protein_coding_gene "0003676=nucleic acid binding, 0004364=glutathione transferase activity, 0043295=glutathione binding" "0046579=positive regulation of Ras protein signal transduction, 0007095=mitotic G2 DNA damage checkpoint, 0070374=positive regulation of ERK1 and ERK2 cascade, 0022008=neurogenesis" 0005737=cytoplasm "GFZF, dGFZF, Suppressor of Killer of prune, CG31492, CG33546, CG31329, cg10065, CG10065, lethal (3) 84Cc, Su(Kpn), l(3)84Cc" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR004046=Glutathione S-transferase, C-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR007588=Zinc finger, FLYWCH-type" CG33546 16-Dec-15 2015_12 DRSC12506 I -1.368200364 -2.331916139 -0.757068307 -0.032619127 0.525888467 -0.276407695 FBgn0001952 l(2)28Aa lethal (2) 28Aa http://flybase.net/reports/FBgn0001952.html gene "J, Complementation group J" 16-Dec-15 2015_12 lethal "wing vein,wing hair,sex comb" FBgn0041710 yellow-f yellow-f http://flybase.net/reports/FBgn0041710.html FBgn0038104 protein_coding_gene 0004167=dopachrome isomerase activity "0042435=indole-containing compound biosynthetic process, 0042438=melanin biosynthetic process, 0048066=developmental pigmentation, 0006583=melanin biosynthetic process from tyrosine, 0048067=cuticle pigmentation" 0005576=extracellular region "yellow f, yell-f, CG18550" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017996=Major royal jelly protein/Protein yellow" CG18550 16-Dec-15 2015_12 viable FBgn0264267 CR43767 http://flybase.net/reports/FBgn0264267.html non_protein_coding_gene CR43767 16-Dec-15 2015_12 FBgn0052988 CG32988 http://flybase.net/reports/FBgn0052988.html FBgn0040960 protein_coding_gene CG18663 CG32988 16-Dec-15 2015_12 viable FBgn0015518 ms(2)HB30 male sterile (2) HB30 http://flybase.net/reports/FBgn0015518.html gene 16-Dec-15 2015_12 FBgn0065846 l(2)SH0318 lethal (2) SH0318 http://flybase.net/reports/FBgn0065846.html gene l(2)SH2 0318 16-Dec-15 2015_12 "lethal,recessive" FBgn0044462 EP3289 EP3289 http://flybase.net/reports/FBgn0044462.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "germline cell,male,anterior fascicle & synapse,intersegmental nerve" FBgn0262992 CR43300 http://flybase.net/reports/FBgn0262992.html non_protein_coding_gene CR43300 16-Dec-15 2015_12 FBgn0060985 l(3)S028206b lethal (3) S028206b http://flybase.net/reports/FBgn0060985.html gene 0282/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0267590 CR45928 http://flybase.net/reports/FBgn0267590.html non_protein_coding_gene CR45928 16-Dec-15 2015_12 FBgn0003366 sev sevenless http://flybase.net/reports/FBgn0003366.html "FBgn0022796, FBgn0026795, FBgn0026831, FBgn0026832" protein_coding_gene "0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0008288=boss receptor activity, 0005515=protein binding, 0005524=ATP binding" "0042067=establishment of ommatidial planar polarity, 0006468=protein phosphorylation, 0008293=torso signaling pathway, 0045467=R7 cell development, 0046534=positive regulation of photoreceptor cell differentiation, 0045464=R8 cell fate specification, 0018108=peptidyl-tyrosine phosphorylation, 0007465=R7 cell fate commitment, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0045466=R7 cell differentiation, 0008595=anterior/posterior axis specification, embryo, 0045678=positive regulation of R7 cell differentiation" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "HD-265, Sev, 7less, 7LES, DROSEV, SEV, CG18085, Sevenless, CT3980, DROSEV1, sev(AC)[[14]], DmHD-265" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR017441=Protein kinase, ATP binding site, IPR003961=Fibronectin type III, IPR013783=Immunoglobulin-like fold, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR002011=Tyrosine-protein kinase, receptor class II, conserved site, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR000033=LDLR class B repeat, IPR000719=Protein kinase domain" CG18085 16-Dec-15 2015_12 ENSMUSG00000019893(Ros1) ENSG00000047936(ROS1) " adult stage , larval stage | third instar " " imaginal disc

, adult head

" "viable,fertile,neuroanatomy defective,phototaxis defective,wild-type,visual behavior defective,heat sensitive,visible,recessive,lethal,partially,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "photoreceptor cell R7,eye,supernumerary,ommatidium,distal medullary amacrine neuron Dm8,rhabdomere R7,heat sensitive,photoreceptor cell R8,photoreceptor cell R8 of yellow ommatidium,ectopic,photoreceptor cell R7 of pale ommatidium,photoreceptor cell,photoreceptor cell R8 of pale ommatidium,pale ommatidium,somatic clone,rhabdomere,photoreceptor cell R6,photoreceptor cell R1,eye photoreceptor cell,denticle belt,embryonic/first instar larval cuticle,embryonic head,cone cell,embryonic/larval tracheal system" FBgn0032129 jp junctophilin http://flybase.net/reports/FBgn0032129.html FBgn0032128 protein_coding_gene 0030314=junctional membrane complex "JP, CG4405, CG13115" IPR003409=MORN motif CG4405 16-Dec-15 2015_12 "ENSDARG00000029590(LOC569861),ENSDARG00000069653,ENSDARG00000059534,ENSDARG00000028625(jph2),ENSDARG00000038826(jph1b),ENSDARG00000058603" WBGene00002179(jph-1) "ENSXETG00000001770(JPH2),ENSXETG00000017402(JPH3),ENSXETG00000011834(jph1)" "ENSMUSG00000017817(Jph2),ENSMUSG00000042686,ENSMUSG00000025318(Jph3)" "ENSG00000104369(JPH1),ENSG00000154118(JPH3),ENSG00000149596(JPH2)" "viable,fertile,lethal" FBgn0266925 CR45376 http://flybase.net/reports/FBgn0266925.html non_protein_coding_gene CR45376 16-Dec-15 2015_12 FBgn0052153 tRNA:CR32153 transfer RNA:CR32153 http://flybase.net/reports/FBgn0052153.html "FBgn0011917, FBgn0003808, FBgn0011918, FBgn0060143" tRNA_gene 0033436=AUG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:met2:72Fb, CR32153, tRNA:met2:72Fa, tRNA:M2:72Fb, chr3L.trna29-MetCAT, AE002602.trna24-MetCAT, tRNA[[2]][Met], transfer RNA:met2:72Fb, tRNA:M:CAT:AE002602-c, transfer RNA:met2:72Fa, tRNA:M2:72Fa" CR32153 16-Dec-15 2015_12 FBgn0034325 CG18539 http://flybase.net/reports/FBgn0034325.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG18539 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0034291 CG5770 http://flybase.net/reports/FBgn0034291.html FBgn0061413 protein_coding_gene BcDNA:LP06072 IPR007931=Protein of unknown function DUF725 CG5770 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0003262 rmp rumpled http://flybase.net/reports/FBgn0003262.html gene rm 16-Dec-15 2015_12 "viable,fertile,visible" "wing,macrochaeta,postvertical bristle" FBgn0087039 Sbp2 SECIS-binding protein 2 http://flybase.net/reports/FBgn0087039.html "FBgn0045076, FBgn0035869" protein_coding_gene "0035613=RNA stem-loop binding, 0035368=selenocysteine insertion sequence binding" 0001514=selenocysteine incorporation 0030529=ribonucleoprotein complex "SECIS Binding Protein 2, CG7066, SBP2" "IPR029064=50S ribosomal protein L30e-like, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45" CG7066 16-Dec-15 2015_12 FBgn0278604 dmt dalmatian http://flybase.net/reports/FBgn0278604.html "FBgn0084681, FBgn0016792, FBgn0062098" protein_coding_gene "0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0007431=salivary gland development, 0007399=nervous system development, 0007064=mitotic sister chromatid cohesion, 0043066=negative regulation of apoptotic process, 0007428=primary branching, open tracheal system, 0060438=trachea development, 0071478=cellular response to radiation" "0000785=chromatin, 0000792=heterochromatin, 0005634=nucleus" "Dalmatian, s048103, anon-WO0118547.317, CG8374, Dmt, anduril, aul, 0481/03" IPR018605=Sororin protein CG8374 16-Dec-15 2015_12 DRSC16932 E -0.20827368 -1.479261786 -0.70036734 -2.705504916 -0.254537113 -0.387448276 FBgn0043799 CG31381 http://flybase.net/reports/FBgn0043799.html FBgn0051381 protein_coding_gene 0046872=metal ion binding 0006400=tRNA modification BEST:LD10347 "IPR018022=tRNA dimethylallyltransferase, IPR022755=Zinc finger, double-stranded RNA binding, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG31381 16-Dec-15 2015_12 ENSDARG00000032876(si:ch211-194e15.1) YOR274W(MOD5) WBGene00001740(gro-1) ENSXETG00000010952(trit1) ENSMUSG00000028653(Trit1) ENSG00000043514(TRIT1) viable FBgn0259759 ms(3)Z5802 http://flybase.net/reports/FBgn0259759.html gene "0007283=spermatogenesis, 0051276=chromosome organization" "167-072, ms(3)167-72" 16-Dec-15 2015_12 "viable,male sterile" Y chromosome loop FBgn0065044 wkp weak processes http://flybase.net/reports/FBgn0065044.html gene 0016319=mushroom body development 16-Dec-15 2015_12 "neuroanatomy defective,somatic clone" "embryonic/larval mushroom body,somatic clone" FBgn0037526 CG10092 http://flybase.net/reports/FBgn0037526.html protein_coding_gene "0004814=arginine-tRNA ligase activity, 0005524=ATP binding" 0006420=arginyl-tRNA aminoacylation 0005739=mitochondrion "atl, arginyl tRNA ligase" "IPR008909=DALR anticodon binding, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR001278=Arginine-tRNA ligase, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site" CG10092 16-Dec-15 2015_12 ENSDARG00000032277(rars2) "YHR091C(MSR1),YDR341C()" WBGene00004680(rars-2) ENSXETG00000019802(RARS2) ENSMUSG00000028292(Rars2) ENSG00000146282(RARS2) "visible,recessive,somatic clone" "eye,somatic clone,eye disc" DRSC14186 IK 2.61426818 -0.490853208 0.056437149 0.339983349 2.935498272 -0.209491786 FBgn0083947 CG34111 http://flybase.net/reports/FBgn0083947.html FBgn0040592 protein_coding_gene CG13825 16-Dec-15 2015_12 viable FBgn0060859 l(3)S047909 lethal (3) S047909 http://flybase.net/reports/FBgn0060859.html gene 0479/09 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262413 mir-9b mir-9b stem loop http://flybase.net/reports/FBgn0262413.html "FBgn0067679, FBgn0262253" miRNA_gene 0008587=imaginal disc-derived wing margin morphogenesis "mir-9, miR-9, pri-miR-9b, mir-9B, CR33563, miR-9b, CR42960, miR9b, mir-9b, 9b, miRNA-9b, dme-mir-9b" CR42960 16-Dec-15 2015_12 embryonic stage -- adult stage "visible,lethal" "eye,wing,wing margin,wing margin bristle,triple row" FBgn0039490 CG5882 http://flybase.net/reports/FBgn0039490.html protein_coding_gene CG5882 16-Dec-15 2015_12 ENSDARG00000069435 ENSMUSG00000046585(Ccdc147) ENSG00000120051(CCDC147) "viable,visible" "chaeta,supernumerary" FBgn0039491 CG6059 http://flybase.net/reports/FBgn0039491.html protein_coding_gene CG6059 16-Dec-15 2015_12 viable FBgn0014184 Oda Ornithine decarboxylase antizyme http://flybase.net/reports/FBgn0014184.html "FBgn0010521, FBgn0014270" protein_coding_gene 0008073=ornithine decarboxylase inhibitor activity 0030154=cell differentiation "0005654=nucleoplasm, 0005829=cytosol" "antizyme, l(2)k09037, ornithine decarboxylase antizyme, orthinine decarboyxlase antizyme, l(2)02833, AZ, guf, gut feeling, Ornithine Deacarboxylase Antizyme, oda, gutfeeling, Antizyme, CG16747, ODA, D-AZ" "IPR002993=Ornithine decarboxylase antizyme, IPR029918=Ornithine decarboxylase antizyme, invertebrates, IPR016181=Acyl-CoA N-acyltransferase" CG16747 16-Dec-15 2015_12 ENSXETG00000013655(BC059754.1) "ENSMUSG00000035242(Oaz1),ENSMUSG00000040652(Oaz2-ps),ENSMUSG00000028141(Oaz3)" "ENSG00000143450(OAZ3),ENSG00000180304(OAZ2),ENSG00000104904(OAZ1)" " embryonic stage | early , embryonic stage | stage >=14 , embryonic stage | stage 7-11 , embryonic stage | stage >=11 , embryonic stage -- adult stage , embryonic stage , embryonic stage | stage 12 " "

ubiquitous , embryonic/larval somatic muscle

, mesoderm

, embryonic/larval midgut

, fat body primordium

, embryonic/larval foregut

, Malpighian tubule primordium

, posterior midgut proper primordium

, embryonic peripheral nervous system

" "viable,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval salivary gland,class IV dendritic arborizing neuron,somatic clone,embryonic/larval brain,embryonic/larval lymph gland,imaginal disc,salivary gland imaginal ring,wing disc,haltere disc,ventral thoracic disc" FBgn0050198 tRNA:CR30198 transfer RNA:CR30198 http://flybase.net/reports/FBgn0050198.html FBgn0060277 tRNA_gene 0033456=GCG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "chr2R.trna50-AlaCGC, tRNA:A:CGC:AE002575-a, tRNA[[Ala]], CR30198, AE002575.trna6-AlaCGC" CR30198 16-Dec-15 2015_12 FBgn0035675 CG6610 http://flybase.net/reports/FBgn0035675.html FBgn0062991 protein_coding_gene 0005515=protein binding "0000398=mRNA splicing, via spliceosome" "0030532=small nuclear ribonucleoprotein complex, 0005681=spliceosomal complex, 0005688=U6 snRNP" BcDNA:RE60135 "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type" CG6610 16-Dec-15 2015_12 ENSDARG00000071573(zgc:171959) YER146W(LSM5) WBGene00003079(lsm-5) ENSXETG00000026465(LSM5) ENSG00000106355(LSM5) FBgn0085659 CG41498 http://flybase.net/reports/FBgn0085659.html FBan0041498 protein_coding_gene 16-Dec-15 2015_12 FBgn0030723 dpr18 defective proboscis extension response 18 http://flybase.net/reports/FBgn0030723.html protein_coding_gene 0007606=sensory perception of chemical stimulus "CT34788, dpr18, CG14948, Dpr18, Dpr-18" "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013151=Immunoglobulin" CG14948 16-Dec-15 2015_12 ENSMUSG00000048534(Amica1) "viable,visible" mesothoracic tergum FBgn0058382 CG40382 http://flybase.net/reports/FBgn0058382.html FBan0040382 protein_coding_gene 16-Dec-15 2015_12 FBgn0051268 CG31268 http://flybase.net/reports/FBgn0051268.html protein_coding_gene IPR008160=Collagen triple helix repeat CG31268 16-Dec-15 2015_12 "viable,fertile" FBgn0264553 CR43932 http://flybase.net/reports/FBgn0264553.html non_protein_coding_gene CR43932 16-Dec-15 2015_12 FBgn0065906 l(2)SH0191 lethal (2) SH0191 http://flybase.net/reports/FBgn0065906.html gene l(2)SH2 0191 16-Dec-15 2015_12 "lethal,recessive" FBgn0030883 CG7772 http://flybase.net/reports/FBgn0030883.html protein_coding_gene 0000266=mitochondrial fission 0005743=mitochondrial inner membrane bs13c01.y1 IPR019560=Mitochondrial 18kDa protein CG7772 16-Dec-15 2015_12 WBGene00077690(mtp-18) ENSXETG00000016147() ENSMUSG00000004748(1700020C11Rik) ENSG00000100010 "viable,fertile" FBgn0265991 Zasp52 Z band alternatively spliced PDZ-motif protein 52 http://flybase.net/reports/FBgn0265991.html "FBgn0083919, FBgn0034042, FBgn0034043, FBgn0034044, FBgn0050084, FBgn0028659" protein_coding_gene "0051371=muscle alpha-actinin binding, 0008270=zinc ion binding, 0005515=protein binding" "0030239=myofibril assembly, 0061061=muscle structure development" "0016323=basolateral plasma membrane, 0045177=apical part of cell, 0045178=basal part of cell, 0005925=focal adhesion, 0030018=Z disc, 0001725=stress fiber, 0031252=cell leading edge, 0005927=muscle tendon junction, 0005915=zonula adherens" "Zasp, tun, Z(210), unnamed, CG12969, Zbp210, CG12968, ZASP52, CG30084, zasp52, zasp, Z band alternatively spliced PDZ-motif protein, dzasp, zetalin, Z-band-protein-210, CG8242, tungus" "IPR001781=Zinc finger, LIM-type, IPR018247=EF-Hand 1, calcium-binding site, IPR006643=ZASP, IPR001478=PDZ domain" CG30084 16-Dec-15 2015_12 WBGene00001132(alp-1) DRSC06269 I -2.114324652 -3.937319585 -1.254712741 -0.048463324 1.252106299 1.1167684 FBgn0033853 CG6145 http://flybase.net/reports/FBgn0033853.html protein_coding_gene 0003951=NAD+ kinase activity "0006741=NADP biosynthetic process, 0048812=neuron projection morphogenesis, 0019674=NAD metabolic process" "0005634=nucleus, 0005737=cytoplasm" CT19307 "IPR002504=NAD kinase, IPR017437=ATP-NAD kinase, PpnK-type, all-beta, IPR017438=Inorganic polyphosphate/ATP-NAD kinase, domain 1, IPR016064=NAD kinase/diacylglycerol kinase-like domain" CG6145 16-Dec-15 2015_12 "ENSDARG00000006577,ENSDARG00000060362(nadk)" "YEL041W(YEF1),YJR049C(UTR1)" ENSXETG00000019605(Q6DJ74_XENTR) ENSMUSG00000029063(Nadk) ENSG00000008130(NADK) viable FBgn0069945 CG41090 http://flybase.net/reports/FBgn0069945.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065857 l(2)SH0288 lethal (2) SH0288 http://flybase.net/reports/FBgn0065857.html gene l(2)SH2 0288 16-Dec-15 2015_12 "lethal,recessive" FBgn0028149 l(3)S044823 lethal (3) S044823 http://flybase.net/reports/FBgn0028149.html gene 0448/23 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0023512 eIF2B-ëµ eIF2B-ëµ http://flybase.net/reports/FBgn0023512.html FBgn0063784 protein_coding_gene "0016779=nucleotidyltransferase activity, 0003743=translation initiation factor activity, 0005085=guanyl-nucleotide exchange factor activity" 0006413=translational initiation "0005829=cytosol, 0005851=eukaryotic translation initiation factor 2B complex" "elf2B-epsilon, CG3806, eIF2B-epsilon, eIF2Bepsilon, EG:86E4.1, eIF-2bepsilon" "IPR005835=Nucleotidyl transferase domain, IPR016024=Armadillo-type fold, IPR001451=Hexapeptide repeat, IPR029044=Nucleotide-diphospho-sugar transferases, IPR003307=W2 domain, IPR016021=MIF4G-like domain" CG3806 16-Dec-15 2015_12 YDR211W(GCD6) WBGene00008428(D2085.3) ENSXETG00000014293(EIF2B5) ENSMUSG00000003235(Eif2b5) ENSG00000145191(EIF2B5) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031109 Obp19a Odorant-binding protein 19a http://flybase.net/reports/FBgn0031109.html protein_coding_gene 0005549=odorant binding "0019236=response to pheromone, 0007606=sensory perception of chemical stimulus, 0042048=olfactory behavior" 0005576=extracellular region "DmelObp19a, odorant-binding protein 19a, 19a, CG11748, OBP19a" IPR006170=Pheromone/general odorant binding protein CG11748 16-Dec-15 2015_12 viable FBgn0028476 Usp1 Ubiquitin specific protease 1 http://flybase.net/reports/FBgn0028476.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" 0005634=nucleus "LD22910, Q8I077, CG15817, BcDNA:LD22910" "IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG15817 16-Dec-15 2015_12 ENSDARG00000056414(usp1) ENSXETG00000013819(USP1) ENSG00000162607(USP1) "viable,fertile,locomotor behavior defective" FBgn0024185 trg trithoraxgleich http://flybase.net/reports/FBgn0024185.html gene 0008354=germ cell migration 16-Dec-15 2015_12 "gonad,precursor" FBgn0265762 CG44569 http://flybase.net/reports/FBgn0265762.html protein_coding_gene CG44569 16-Dec-15 2015_12 FBgn0065306 l(2)SH1968 lethal (2) SH1968 http://flybase.net/reports/FBgn0065306.html gene l(2)SH2 1968 16-Dec-15 2015_12 "lethal,recessive" FBgn0024239 feng feng http://flybase.net/reports/FBgn0024239.html gene 0007411=axon guidance 16-Dec-15 2015_12 FBgn0263330 CR43411 http://flybase.net/reports/FBgn0263330.html non_protein_coding_gene CR43411 16-Dec-15 2015_12 FBgn0067739 l(1)G0314 lethal (1) G0314 http://flybase.net/reports/FBgn0067739.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0061177 bcd::Ubx bcd::Ubx http://flybase.net/reports/FBgn0061177.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0266669 Sec3 Sec3 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266669.html "FBgn0266609, FBgn0086475, FBgn0066325, FBgn0036718" protein_coding_gene "0005546=phosphatidylinositol-4,5-bisphosphate binding" "0016081=synaptic vesicle docking, 0016080=synaptic vesicle targeting" 0000145=exocyst "CG3885, sec3" "IPR028258=Exocyst complex component Sec3, PIP2-binding N-terminal domain, IPR019160=Exocyst complex, component 1/SEC3" CG3885 16-Dec-15 2015_12 ENSDARG00000043019(exoc1) WBGene00018703(sec-3) ENSXETG00000021068(EXOC1) ENSMUSG00000036435(Exoc1) ENSG00000090989(EXOC1) FBgn0060720 l(3)SzB63Cb lethal (3) SzB63Cb http://flybase.net/reports/FBgn0060720.html gene "l(3)S068609a, 0686/09" 16-Dec-15 2015_12 "lethal,lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0083969 CG34133 http://flybase.net/reports/FBgn0083969.html "FBan0007814, FBgn0039715, FBgn0051035, FBgn0062023" protein_coding_gene "CG7814, CG31035, anon-WO0118547.417" "IPR020472=G-protein beta WD-40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG34133 16-Dec-15 2015_12 ENSDARG00000060249(LOC569045) YCR084C(TUP1) WBGene00006369(sym-4) ENSXETG00000003671(WDR44) ENSMUSG00000036769(Wdr44) ENSG00000131725(WDR44) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004202 l(3)84Dd lethal (3) 84Dd http://flybase.net/reports/FBgn0004202.html gene 16-Dec-15 2015_12 lethal FBgn0013707 mt:tRNA:T mitochondrial threonine tRNA http://flybase.net/reports/FBgn0013707.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "tRNA-Thr, CR34087, tRNA[Thr], mtdbD00006309" CR34087 16-Dec-15 2015_12 FBgn0032681 CG10283 http://flybase.net/reports/FBgn0032681.html protein_coding_gene "IPR029311=Coiled-coil domain-containing protein 50, N-terminal" CG10283 16-Dec-15 2015_12 "ENSDARG00000054822,ENSDARG00000053857(zgc:162431)" ENSXETG00000006027() ENSG00000152492(CCDC50) FBgn0065536 l(2)SH1078 lethal (2) SH1078 http://flybase.net/reports/FBgn0065536.html gene l(2)SH2 1078 16-Dec-15 2015_12 "lethal,recessive" FBgn0260793 2mit http://flybase.net/reports/FBgn0260793.html "FBgn0038119, FBgn0038120" protein_coding_gene 0007614=short-term memory "CT38314, CT28541, CG17319, CG42573, CG10148" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG42573 16-Dec-15 2015_12 ENSXETG00000014980() FBgn0001599 l(1)CP9 lethal (1) CP9 http://flybase.net/reports/FBgn0001599.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030947 CG6696 http://flybase.net/reports/FBgn0030947.html protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis 0017090=meprin A complex "IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR001506=Peptidase M12A, astacin" CG6696 16-Dec-15 2015_12 "WBGene00003526(nas-7),WBGene00003527(nas-8),WBGene00003534(nas-15)" ENSXETG00000015923() ENSMUSG00000050468(Astl) ENSG00000188886(ASTL) "viable,visible" mesothoracic tergum FBgn0032132 CG4382 http://flybase.net/reports/FBgn0032132.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR029058=Alpha/Beta hydrolase fold, IPR002018=Carboxylesterase, type B" CG4382 16-Dec-15 2015_12 "ENSDARG00000041595(ces3),ENSDARG00000041569(ces2),ENSDARG00000070915" "ENSMUSG00000031877(2210023G05Rik),ENSMUSG00000061825(Ces2),ENSMUSG00000050097(BC015286),ENSMUSG00000031884(Gm9756),ENSMUSG00000031886(Ces5),ENSMUSG00000055730(Ces6),ENSMUSG00000062826(2310038E17Rik),ENSMUSG00000056973(Ces3),ENSMUSG00000061959(Es22),ENSMUSG00000057074(Ces1),ENSMUSG00000057400(Es1),ENSMUSG00000078964(Gm5158),ENSMUSG00000031725(AU018778),ENSMUSG00000071047(Gm4976),ENSMUSG00000074156(2310039D24Rik),ENSMUSG00000069922(Es31),ENSMUSG00000062181(Gm4738),ENSMUSG00000060560(Ces8),ENSMUSG00000058019(Ces7)" "viable,visible" "wing vein,ectopic" FBgn0000288 cff control of female fertility http://flybase.net/reports/FBgn0000288.html gene cf 16-Dec-15 2015_12 FBgn0016761 Z(400-600) Z-band-protein-400/600 http://flybase.net/reports/FBgn0016761.html gene "unnamed, Z(400/600), Zbp400/600" 16-Dec-15 2015_12 FBgn0024319 Nach Nach http://flybase.net/reports/FBgn0024319.html protein_coding_gene 0005272=sodium channel activity "0006814=sodium ion transport, 0035002=liquid clearance, open tracheal system" 0016021=integral component of membrane "pickpocket 4, ppk4, CG8178, PPK4" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG8178 16-Dec-15 2015_12 WBGene00006748(unc-8) "ENSXETG00000012423(SCNN1G),ENSXETG00000027567(SCNN1B)" "ENSMUSG00000000216(Scnn1g),ENSMUSG00000030873(Scnn1b)" "ENSG00000166828(SCNN1G),ENSG00000168447(SCNN1B)" "viable,lethal" adult tracheal system FBgn0065569 l(2)SH0971 lethal (2) SH0971 http://flybase.net/reports/FBgn0065569.html gene l(2)SH2 0971 16-Dec-15 2015_12 "lethal,recessive" FBgn0060887 l(3)S044632b lethal (3) S044632b http://flybase.net/reports/FBgn0060887.html gene 0446/32 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0011776 l(2)25Eg lethal (2) 25Eg http://flybase.net/reports/FBgn0011776.html gene "l(2)gdh1, Df(2L)sc19-4, l(2)gdh-1" 16-Dec-15 2015_12 "lethal,recessive" FBgn0267482 CR45832 http://flybase.net/reports/FBgn0267482.html non_protein_coding_gene CR45832 16-Dec-15 2015_12 FBgn0039760 CG9682 http://flybase.net/reports/FBgn0039760.html FBgn0044629 protein_coding_gene anon-WO0140519.240 CG9682 16-Dec-15 2015_12 viable FBgn0260619 2L2983 http://flybase.net/reports/FBgn0260619.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0043887 l(3)S118502b lethal (3) S118502b http://flybase.net/reports/FBgn0043887.html gene "1185/02, l(3)S118502" 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0061170 l(1)12Da lethal (1) 12Da http://flybase.net/reports/FBgn0061170.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037687 CG8132 http://flybase.net/reports/FBgn0037687.html protein_coding_gene 0000257=nitrilase activity 0006807=nitrogen compound metabolic process IPR003010=Carbon-nitrogen hydrolase CG8132 16-Dec-15 2015_12 ENSDARG00000017590(nit2) YLR351C(NIT3) ENSXETG00000011864(nit2) ENSMUSG00000022751(Nit2) ENSG00000114021(NIT2) "viable,fertile" FBgn0261807 CG42753 http://flybase.net/reports/FBgn0261807.html protein_coding_gene CG42753 16-Dec-15 2015_12 FBgn0086601 snoRNA:ë¬28S-3327c snoRNA:ë¬28S-3327c http://flybase.net/reports/FBgn0086601.html "FBgn0053753, FBgn0065062, FBgn0082965" snoRNA_gene 0005730=nucleolus "pug28S-3327, CR33753, Psi28S-3327c, chr3L:13017350..13017456, snoRNA:586, Dm-586, psi28S-3327c, snoR586" CR33753 16-Dec-15 2015_12 FBgn0263889 l(3)D67 http://flybase.net/reports/FBgn0263889.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0011882 tRNA:I:49Fb transfer RNA:ile:49Fb http://flybase.net/reports/FBgn0011882.html "FBgn0003788, FBgn0050244, FBgn0060199" tRNA_gene "0033433=AUU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2R.trna19-IleAAT, tRNA:ile:49Fb, CR30244, tRNA[Ile], Transfer RNA:ile:49Fb, AE002787.trna37-IleAAT, ile-b, tRNA:I:AAT:AE002787-c" CR30244 16-Dec-15 2015_12 FBgn0002627 M(3)99E Minute (3) 99E http://flybase.net/reports/FBgn0002627.html gene "M(3)g, M[[g]]" 16-Dec-15 2015_12 "visible,dominant" "posterior dorsocentral bristle,posterior scutellar bristle,femur & macrochaeta" FBgn0039651 Cyt-c1L Cytochrome c1-like http://flybase.net/reports/FBgn0039651.html protein_coding_gene "0020037=heme binding, 0045153=electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity" "0006119=oxidative phosphorylation, 0006122=mitochondrial electron transport, ubiquinol to cytochrome c" 0005750=mitochondrial respiratory chain complex III "Ubiquinol-cytochrome c reductase Cytochrome C1, heme protein, CY1, Cytochrome c1, heme protein, mitochondrial, CG14508" "IPR002326=Cytochrome c1, IPR009056=Cytochrome c-like domain, IPR021157=Cytochrome c1, transmembrane anchor, C-terminal" CG14508 16-Dec-15 2015_12 ENSDARG00000038075(cyc1) YOR065W(CYT1) WBGene00000869(cyc-1) ENSMUSG00000022551(Cyc1) ENSG00000179091(CYC1) FBgn0011555 ëüTry ëüTrypsin http://flybase.net/reports/FBgn0011555.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "Try, thetaTrypsin, thetaTry, SP139, DmThetaTry, CG12385" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG12385 16-Dec-15 2015_12 "ENSDARG00000039728(ctrb1),ENSDARG00000018367(zgc:136461),ENSDARG00000039730(zgc:112160),ENSDARG00000068680(ctrl),ENSDARG00000010378(zgc:171592)" viable FBgn0001424 l(1)6Dh lethal (1) 6Dh http://flybase.net/reports/FBgn0001424.html gene 16-Dec-15 2015_12 lethal FBgn0036825 RpL26 Ribosomal protein L26 http://flybase.net/reports/FBgn0036825.html protein_coding_gene 0003735=structural constituent of ribosome "0000022=mitotic spindle elongation, 0006412=translation, 0007052=mitotic spindle organization" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "Rp L26, RPL26, L26, lincRNA.S5499, CG6846" "IPR005824=KOW, IPR005756=Ribosomal protein L26/L24P, eukaryotic/archaeal, IPR005825=Ribosomal protein L24/L26, conserved site, IPR014722=Ribosomal protein L2 domain 2, IPR008991=Translation protein SH3-like domain" CG6846 16-Dec-15 2015_12 ENSDARG00000039641(rpl26) "YGR034W(RPL26B),YLR344W(RPL26A)" WBGene00004440(rpl-26) ENSXETG00000024782(rpl26) "ENSMUSG00000060938(Rpl26),ENSMUSG00000063754(Gm10136),ENSMUSG00000059150(Rpl26-ps4),ENSMUSG00000066489(Rpl26-ps2)" "ENSG00000037241(RPL26L1),ENSG00000161970(RPL26)" lethal DRSC10726 IEK -0.323388734 -1.79363646 2.129367017 -4.48033862 0.524731367 1.66337956 FBgn0082612 T:SS-Drs Signal sequence of Drosomycin http://flybase.net/reports/FBgn0082612.html engineered_tag "Drosomycin signal sequence, T:Drs" 16-Dec-15 2015_12 FBgn0264792 CR44022 http://flybase.net/reports/FBgn0264792.html non_protein_coding_gene CR44022 16-Dec-15 2015_12 FBgn0031229 CG3436 http://flybase.net/reports/FBgn0031229.html protein_coding_gene 0044822=poly(A) RNA binding "0007067=mitotic nuclear division, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0071013=catalytic step 2 spliceosome, 0005682=U5 snRNP" "IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site" CG3436 16-Dec-15 2015_12 ENSDARG00000023160(snrnp40) "WBGene00008586(F08G12.2),WBGene00015974(C18E3.5)" ENSXETG00000012910(wdr57) ENSMUSG00000074088(Snrnp40) ENSG00000060688(SNRNP40) viable DRSC00605 E 0.55168266 -0.624085032 3.05702244 -0.861831248 1.254604501 1.12681866 FBgn0001121 Go Gold tip http://flybase.net/reports/FBgn0001121.html gene 16-Dec-15 2015_12 "visible,dominant,cold sensitive,lethal,recessive" "trichome,cold sensitive,macrochaeta" FBgn0020541 l(2)DTS4 lethal (2) DTS4 http://flybase.net/reports/FBgn0020541.html gene DTSL4 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,dominant,heat sensitive,some die during pupal stage" FBgn0265468 CR44361 http://flybase.net/reports/FBgn0265468.html non_protein_coding_gene CR44361 16-Dec-15 2015_12 FBgn0004628 CabP23 Calcium-binding protein 23kD http://flybase.net/reports/FBgn0004628.html FBgn0004121 gene 0005509=calcium ion binding 16-Dec-15 2015_12 " adult stage , adult stage && oogenesis stage " " ovary

, pupal/adult digestive system

, adult head

" FBgn0015824 T-B9.3 T-B9.3 http://flybase.net/reports/FBgn0015824.html gene 16-Dec-15 2015_12 FBgn0085759 CR40640 http://flybase.net/reports/FBgn0085759.html FBan0040640 rRNA_gene CR40640 16-Dec-15 2015_12 FBgn0085309 CG34280 http://flybase.net/reports/FBgn0085309.html protein_coding_gene IPR002350=Kazal domain CG34280 16-Dec-15 2015_12 FBgn0035086 CG12851 http://flybase.net/reports/FBgn0035086.html protein_coding_gene CG12851 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC04131 K 0.032654993 0.150901008 -0.480427001 0.077997968 2.978870617 -0.238076377 FBgn0038128 Ravus Ravus http://flybase.net/reports/FBgn0038128.html protein_coding_gene 0003677=DNA binding 0000790=nuclear chromatin CG15889 IPR004210=BESS motif CG15889 16-Dec-15 2015_12 "non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0051118 RabX4 RabX4 http://flybase.net/reports/FBgn0051118.html FBgn0039231 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport" "0045202=synapse, 0043025=neuronal cell body, 0055037=recycling endosome, 0031982=vesicle" "AAF56345, CG13638, CG31118, DmRabX4, rabX4" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type" CG31118 16-Dec-15 2015_12 FBgn0016000 l(3)2h lethal (3) 2h http://flybase.net/reports/FBgn0016000.html gene l(3L)2h 16-Dec-15 2015_12 FBgn0038241 CG8087 http://flybase.net/reports/FBgn0038241.html protein_coding_gene CG8087 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031468 CG2975 http://flybase.net/reports/FBgn0031468.html protein_coding_gene "0048531=beta-1,3-galactosyltransferase activity" "0006486=protein glycosylation, 0032504=multicellular organism reproduction" 0016021=integral component of membrane dC1GalT4 IPR003378=Fringe-like CG2975 16-Dec-15 2015_12 viable FBgn0004670 Crown Crown http://flybase.net/reports/FBgn0004670.html gene Crn 16-Dec-15 2015_12 "lethal,recessive,visible,dominant,body color defective" FBgn0083026 snoRNA:ë¬18S-640a snoRNA:ë¬18S-640a http://flybase.net/reports/FBgn0083026.html snoRNA_gene "psi18s-640a, CR34571, Psi 18S-640a" CR34571 16-Dec-15 2015_12 FBgn0266348 CR44997 http://flybase.net/reports/FBgn0266348.html non_protein_coding_gene CR44997 16-Dec-15 2015_12 FBgn0259313 EP-1008 http://flybase.net/reports/FBgn0259313.html gene 16-Dec-15 2015_12 visible wing vein FBgn0039737 CG7920 http://flybase.net/reports/FBgn0039737.html "FBgn0045917, FBgn0045918, FBgn0046309" protein_coding_gene 0008411=4-hydroxybutyrate CoA-transferase activity "0006084=acetyl-CoA metabolic process, 0022008=neurogenesis" "0005829=cytosol, 0005739=mitochondrion, 0005811=lipid particle" "BEST:GH02390, i130, anon-WO0153538.37, anon-WO0153538.36, GH02390.5prime, 4-hydroxybutyrate Co-A transferase" "IPR003702=Acetyl-CoA hydrolase/transferase, IPR026888=Acetyl-CoA hydrolase/transferase C-terminal domain" CG7920 16-Dec-15 2015_12 WBGene00016630(C44B7.10) ENSXETG00000019876() "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0002702 fme focal melanosis http://flybase.net/reports/FBgn0002702.html gene me 16-Dec-15 2015_12 "lethal,visible" "femur,tibia" FBgn0039656 CG11951 http://flybase.net/reports/FBgn0039656.html protein_coding_gene "0008270=zinc ion binding, 0004177=aminopeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis "IPR024571=ERAP1-like C-terminal domain, IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG11951 16-Dec-15 2015_12 "viable,fertile" FBgn0264818 CR44026 http://flybase.net/reports/FBgn0264818.html non_protein_coding_gene CR44026 16-Dec-15 2015_12 FBgn0065100 snmRNA:254 small non-messenger RNA 254 http://flybase.net/reports/FBgn0065100.html FBgn0053705 non_protein_coding_gene "chr2L:21668100..21668302, CR33705, Dm-254" CR33705 16-Dec-15 2015_12 FBgn0053923 CG33923 http://flybase.net/reports/FBgn0053923.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33923 16-Dec-15 2015_12 FBgn0039924 PIP4K Phosphatidylinositol 5-phosphate 4-kinase http://flybase.net/reports/FBgn0039924.html protein_coding_gene "0016308=1-phosphatidylinositol-4-phosphate 5-kinase activity, 0016309=1-phosphatidylinositol-5-phosphate 4-kinase activity" "0007015=actin filament organization, 0007155=cell adhesion, 0040018=positive regulation of multicellular organism growth, 0032006=regulation of TOR signaling, 0046854=phosphatidylinositol phosphorylation, 0016310=phosphorylation, 0030307=positive regulation of cell growth, 0008360=regulation of cell shape" 0005886=plasma membrane "dPIP4K, phosphatidylinositol 5-phosphate 4-kinase, PIP5K 102E, CG17471" "IPR023610=Phosphatidylinositol-4-phosphate 5-kinase, IPR027483=Phosphatidylinositol-4-phosphate 5-kinase, C-terminal, IPR027484=Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR002498=Phosphatidylinositol-4-phosphate 5-kinase, core" CG17471 16-Dec-15 2015_12 "ENSDARG00000031020(pip5k2),ENSDARG00000063544(LOC555920),ENSDARG00000003776(LOC560360)" WBGene00004088(ppk-2) "ENSXETG00000023725(PIP5K2B),ENSXETG00000006229(pip5k2c)" "ENSMUSG00000018547(Pip4k2b),ENSMUSG00000026737(Pip4k2a),ENSMUSG00000025417(Pip4k2c)" "ENSG00000141720(PIP4K2B),ENSG00000150867(PIP4K2A),ENSG00000166908(PIP4K2C)" "small body,developmental rate defective,decreased cell size,large body,increased cell size" "embryonic/larval salivary gland,embryonic/larval salivary gland | larval stage" FBgn0001917 l(2)25Bd lethal (2) 25Bd http://flybase.net/reports/FBgn0001917.html gene "l(2)jf13, jf13" 16-Dec-15 2015_12 lethal FBgn0264668 truncated truncated http://flybase.net/reports/FBgn0264668.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040827 CG13315 http://flybase.net/reports/FBgn0040827.html FBgn0064815 protein_coding_gene BcDNA:RH39779 CG13315 16-Dec-15 2015_12 viable FBgn0038850 CG17279 http://flybase.net/reports/FBgn0038850.html protein_coding_gene 0005615=extracellular space IPR010562=Haemolymph juvenile hormone binding CG17279 16-Dec-15 2015_12 FBgn0002772 Mlc1 Myosin alkali light chain 1 http://flybase.net/reports/FBgn0002772.html protein_coding_gene "0000146=microfilament motor activity, 0005509=calcium ion binding" "0006936=muscle contraction, 0007498=mesoderm development" "0005859=muscle myosin complex, 0016459=myosin complex, 0005829=cytosol" "Myosin, Myosin Light Chain-1, Myosin alkali light chain l, CG5596, myosin light chain, DmMLC1, ELC, mlc, LC1, Mlc-1, mlcl, MLC, Myosin light chain alkali, FBgn0002772, Myosin 3R alkali light chain l, chr3R:23484557..23484663, MlcI, MLC1, Mlci, mlc-alk, MLC-ALK, mlc1" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR029655=Myosin light chain alkali" CG5596 16-Dec-15 2015_12 " adult stage ,, pupal stage | late , larval stage && adult stage , embryonic stage | late , larval stage " " tubular muscle

, indirect flight muscle

" " larval stage , adult stage " " tubular muscle

, adult abdomen

, adult head

, leg

, indirect flight muscle

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0069245 cst croissant http://flybase.net/reports/FBgn0069245.html gene "0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded" 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect" FBgn0032734 CG15169 http://flybase.net/reports/FBgn0032734.html protein_coding_gene CG15169 16-Dec-15 2015_12 viable FBgn0065739 l(2)SH0529 lethal (2) SH0529 http://flybase.net/reports/FBgn0065739.html gene l(2)SH2 0529 16-Dec-15 2015_12 "lethal,recessive" FBgn0005032 e(N8) enhancer of Notch-8 http://flybase.net/reports/FBgn0005032.html gene 16-Dec-15 2015_12 wing FBgn0043796 CG12219 http://flybase.net/reports/FBgn0043796.html FBgn0029862 protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" 0005634=nucleus BEST:LD26135 "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR015880=Zinc finger, C2H2-like" CG12219 16-Dec-15 2015_12 "ENSG00000158805(ZNF276),ENSG00000161914(ZNF653)" viable DRSC24690 K -0.220727953 0.896963033 -0.405255396 0.762622391 -1.649840128 -0.004041397 FBgn0265645 CR44452 http://flybase.net/reports/FBgn0265645.html non_protein_coding_gene lincRNA.279 CR44452 16-Dec-15 2015_12 FBgn0000133 Ars-region11 Autonomous replicating sequence region 11 http://flybase.net/reports/FBgn0000133.html region "Ars11, Ars sequence 11, DmARS-6" 16-Dec-15 2015_12 FBgn0259540 B2008 http://flybase.net/reports/FBgn0259540.html gene 16-Dec-15 2015_12 visible "anterior crossvein,tarsal segment,arista,unguis" FBgn0264554 CR43933 http://flybase.net/reports/FBgn0264554.html non_protein_coding_gene CG43933 CR43933 16-Dec-15 2015_12 FBgn0260364 GSd500 http://flybase.net/reports/FBgn0260364.html gene 16-Dec-15 2015_12 lethal FBgn0020839 l(2)CP241 "Canonsburg, PA 241" http://flybase.net/reports/FBgn0020839.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029765 CG16756 http://flybase.net/reports/FBgn0029765.html FBgn0047033 protein_coding_gene 0003796=lysozyme activity 0019730=antimicrobial humoral response BcDNA:RH17440 "IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain, IPR019799=Glycoside hydrolase, family 22, conserved site" CG16756 16-Dec-15 2015_12 ENSDARG00000057789(lyz) "ENSG00000151033(LYZL2),ENSG00000120563(LYZL1),ENSG00000141316(SPACA3),ENSG00000171478(SPACA5B),ENSG00000171489(SPACA5),ENSG00000161572(LYZL6),ENSG00000157093(LYZL4)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0260380 GSd406 http://flybase.net/reports/FBgn0260380.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve" FBgn0020560 anon-VIII-E7 anon-VIII-E7 http://flybase.net/reports/FBgn0020560.html gene 16-Dec-15 2015_12 Bolwig nerve FBgn0000648 fd furled http://flybase.net/reports/FBgn0000648.html gene 16-Dec-15 2015_12 visible "proboscis,mouthpart" FBgn0035924 CG6576 http://flybase.net/reports/FBgn0035924.html protein_coding_gene CG6576 16-Dec-15 2015_12 viable FBgn0032436 CG5418 http://flybase.net/reports/FBgn0032436.html protein_coding_gene "IPR001910=Inosine/uridine-preferring nucleoside hydrolase domain, IPR023186=Inosine/uridine-preferring nucleoside hydrolase" CG5418 16-Dec-15 2015_12 "ENSDARG00000042124(si:dkey-4e7.3),ENSDARG00000056203(si:dkey-98p3.7)" YDR400W(URH1) "WBGene00012834(Y43F8C.13),WBGene00017436(F13H8.3)" "ENSXETG00000000637(BC090126.1),ENSXETG00000019416(TGas057p14.1)" viable FBgn0037023 CG3698 http://flybase.net/reports/FBgn0037023.html protein_coding_gene CG3698 16-Dec-15 2015_12 viable FBgn0060780 l(3)S060706 lethal (3) S060706 http://flybase.net/reports/FBgn0060780.html gene 0607/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0020363 anon-1A1 anon-1A1 http://flybase.net/reports/FBgn0020363.html gene 1A1 16-Dec-15 2015_12 FBgn0032882 Ns4 Nucleostemin ortholog (H. sapiens) 4 http://flybase.net/reports/FBgn0032882.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0042254=ribosome biogenesis 0005829=cytosol "CG9320, dmNS4, nucleostemin 4, NS4, 38E.14, ns4" "IPR030378=Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006073=GTP binding domain" CG9320 16-Dec-15 2015_12 ENSDARG00000061789(gnl1) ENSXETG00000024087(GNL1) ENSMUSG00000024429(Gnl1) "ENSG00000206412,ENSG00000206492,ENSG00000204590(GNL1)" "viable,fertile" FBgn0032052 PIG-U "Phosphatidylinositol glycan anchor biosynthesis, class U ortholog (H. sapiens)" http://flybase.net/reports/FBgn0032052.html protein_coding_gene "0042996=regulation of Golgi to plasma membrane protein transport, 0006506=GPI anchor biosynthetic process" 0016021=integral component of membrane CG13089 IPR009600=GPI transamidase subunit PIG-U CG13089 16-Dec-15 2015_12 YLR459W(GAB1) WBGene00011914(T22C1.3) ENSXETG00000019472(cdc91l1) ENSMUSG00000038383(Pigu) ENSG00000101464(PIGU) "viable,visible" "rhabdomere,somatic clone,trichogen cell" FBgn0038304 CG12241 http://flybase.net/reports/FBgn0038304.html protein_coding_gene 0005096=GTPase activator activity "IPR004012=RUN domain, IPR000195=Rab-GTPase-TBC domain, IPR001452=SH3 domain" CG12241 16-Dec-15 2015_12 ENSDARG00000019038(sgsm3) WBGene00018281(tbc-18) ENSXETG00000006329(SGSM3) ENSMUSG00000042303(Sgsm3) ENSG00000100359(SGSM3) DRSC14481 E 1.164780678 0.64435379 1.800264879 -0.144473291 -0.696742662 -0.266888965 FBgn0267458 CR45808 http://flybase.net/reports/FBgn0267458.html non_protein_coding_gene CR45808 16-Dec-15 2015_12 FBgn0037204 CG11131 http://flybase.net/reports/FBgn0037204.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "IPR004019=YLP motif, IPR004011=GYR motif" CG11131 16-Dec-15 2015_12 viable FBgn0014944 anon-99A anon-99A http://flybase.net/reports/FBgn0014944.html gene unnamed 16-Dec-15 2015_12 FBgn0038548 CG17806 http://flybase.net/reports/FBgn0038548.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR003604=Zinc finger, U1-type, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG17806 16-Dec-15 2015_12 WBGene00004335(ref-2) "viable,fertile" FBgn0082949 snoRNA:Me18S-U1356a snoRNA:Me18S-U1356a http://flybase.net/reports/FBgn0082949.html snoRNA_gene "Me18S-Um1356a, CR34644, Me18S-U1356a" CR34644 16-Dec-15 2015_12 FBgn0005054 fs(1)ne13 female sterile (1) no eggs 13 http://flybase.net/reports/FBgn0005054.html gene "ne13, fs(1)ne[13]" 16-Dec-15 2015_12 "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0260470 SP555 SP555 http://flybase.net/reports/FBgn0260470.html "FBgn0040280, FBgn0031671, FBan0014041, FBgn0031672, FBgn0045318, FBgn0063746" protein_coding_gene 0035556=intracellular signal transduction "CG14041, dmSSBa, BcDNA:AT09933, NEST:bs13e02" "IPR003877=SPRY domain, IPR001496=SOCS box domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001870=B30.2/SPRY domain" CG14041 16-Dec-15 2015_12 DRSC02367 E 0.249012002 1.134647573 1.527442319 0.407993433 0.210067434 -0.775739987 FBgn0038583 CG7183 http://flybase.net/reports/FBgn0038583.html protein_coding_gene IPR025066=Protein of unknown function DUF4078 CG7183 16-Dec-15 2015_12 ENSDARG00000023858(zgc:113409) ENSXETG00000004821(C3orf19) ENSMUSG00000034083(C130022K22Rik) ENSG00000154781(C3orf19) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069924 CG41127 http://flybase.net/reports/FBgn0069924.html FBan0041127 protein_coding_gene 16-Dec-15 2015_12 FBgn0002476 l(3)SG31 lethal (3) SG31 http://flybase.net/reports/FBgn0002476.html FBgn0004718 gene "l(3)B14, l(3)ds14, l(3)2612" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle,mitosis & nuclear chromosome,mitotic cell cycle" FBgn0032109 CG17005 http://flybase.net/reports/FBgn0032109.html protein_coding_gene CG17005 16-Dec-15 2015_12 viable FBgn0086917 spok spookier http://flybase.net/reports/FBgn0086917.html "FBgn0086781, FBgn0041338, FBgn0058123, FBan0041624, FBgn0085726" protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0016491=oxidoreductase activity, 0020037=heme binding" "0006697=ecdysone biosynthetic process, 0055114=oxidation-reduction process, 0007591=molting cycle, chitin-based cuticle" "307a2p, Cyp307a2, cytochrome P450, CG40123, Dmspok, spook 2, CYP307A2, CG41624, Cyp307a2p, Cyp307a2Psi, spo2" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG41624 16-Dec-15 2015_12 FBgn0062531 l(3)02727a lethal (3) 02727a http://flybase.net/reports/FBgn0062531.html gene P02727 16-Dec-15 2015_12 "lethal,recessive" FBgn0036023 CG18179 http://flybase.net/reports/FBgn0036023.html FBgn0043787 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BEST:LP02275, SP152" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG18179 16-Dec-15 2015_12 viable FBgn0083149 S(smoDN)2629 Suppressor of smoDN 2629 http://flybase.net/reports/FBgn0083149.html gene 16-Dec-15 2015_12 FBgn0003090 pk prickle http://flybase.net/reports/FBgn0003090.html "FBgn0003477, FBgn0033151, FBgn0040783" protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding" "0001738=morphogenesis of a polarized epithelium, 0045185=maintenance of protein location, 0007163=establishment or maintenance of cell polarity, 0008104=protein localization, 0045773=positive regulation of axon extension, 0045746=negative regulation of Notch signaling pathway, 0042067=establishment of ommatidial planar polarity, 0016348=imaginal disc-derived leg joint morphogenesis, 0001736=establishment of planar polarity, 0001737=establishment of imaginal disc-derived wing hair orientation, 0045184=establishment of protein localization, 1902669=positive regulation of axon guidance" "0016020=membrane, 0005737=cytoplasm" "prickle-spiny legs, spiny legs, pkM, CG12830, sple, pk-sple, Pk, CG11084, prickle-spiny-legs, Sple, Prickle, Pk-Sple" "IPR010442=PET domain, IPR001781=Zinc finger, LIM-type" CG11084 16-Dec-15 2015_12 "ENSDARG00000037593(prickle2),ENSDARG00000045694(prickle1b),ENSDARG00000040649(prickle1a),ENSDARG00000020982(zgc:152958)" WBGene00022727(prkl-1) "ENSXETG00000006535(PRICKLE2),ENSXETG00000006797(prickle1)" "ENSMUSG00000030020(Prickle2),ENSMUSG00000036158(Prickle1),ENSMUSG00000031145(Prickle3)" "ENSG00000163637(PRICKLE2),ENSG00000139174(PRICKLE1),ENSG00000012211(PRICKLE3)" " pupal stage | 28-34hr , embryonic stage , larval stage , larval stage | third instar " " wing

, ventral midline

, imaginal disc

, morphogenetic furrow | posterior to

, leg

, cephalic furrow

, dorsal mesothoracic disc

, eye disc

" "visible,recessive,planar polarity defective,visual behavior defective,viable,fertile,cell polarity defective,dominant,cell autonomous,somatic clone,cell non-autonomous,gravitaxis defective,cold sensitive" "ommatidium,tarsal segment 3,tarsal segment 4,tarsal segment 3 & joint,tarsal segment 4 & joint,eye,wing hair,leg & macrochaeta,leg & trichome,wing,scutum,abdomen,leg,joint,ectopic,abdominal tergite & macrochaeta,abdominal sternite & macrochaeta,tarsal segment,triple row,mesothoracic tergum & sensory mother cell & spindle,dorsal wing blade,trichome & costal cell,somatic clone,cell non-autonomous,cell autonomous,trichome & adult abdomen | somatic clone | cell autonomous,wing cell,eye photoreceptor cell,tarsal segment & joint,photoreceptor cell R4,precursor,tarsal segment 1 & joint,tarsal segment 2,abdomen & macrochaeta,trichome,metatarsus,posterior,thorax,wing & cell,anterior,wing & pupa & cellen-e16E,wing hair & cell & pupaen-e16E,tarsal segment 1 & jointda.G32,tarsal segment 1 & jointC-765,wing hair & 1st posterior cellptc-559.1,wing blade,trichome & adult abdomen | posterior compartmentë±Tub84B.PL,trichome & adult abdomen | somatic clone | posterior compartmentë±Tub84B.PL,trichome & adult abdomen" DRSC06178 E -0.938733806 -1.368047133 -1.118800096 2.026803618 0.859928835 1.384656696 FBgn0060828 l(3)S050910 lethal (3) S050910 http://flybase.net/reports/FBgn0060828.html gene 0509/10 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0038191 CG9925 http://flybase.net/reports/FBgn0038191.html protein_coding_gene 0008270=zinc ion binding "0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response" "IPR002999=Tudor domain, IPR002893=Zinc finger, MYND-type" CG9925 16-Dec-15 2015_12 viable FBgn0028092 l(3)S079311b lethal (3) S079311b http://flybase.net/reports/FBgn0028092.html gene "0793/11, l(3)S079311" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037104 CG14574 http://flybase.net/reports/FBgn0037104.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0025478 p40 p40 http://flybase.net/reports/FBgn0025478.html gene 16-Dec-15 2015_12 FBgn0046844 ird24 immune response deficient 24 http://flybase.net/reports/FBgn0046844.html gene 0006959=humoral immune response 16-Dec-15 2015_12 "lethal,recessive,immune response defective" FBgn0005051 fll flyless http://flybase.net/reports/FBgn0005051.html gene 16-Dec-15 2015_12 flight defective FBgn0028866 CG18420 http://flybase.net/reports/FBgn0028866.html FBgn0032552 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BG:DS06874.6, DS06874.6, SPH111" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG18420 16-Dec-15 2015_12 WBGene00006621(try-3) viable FBgn0250743 l(3)S113302 lethal (3) S113302 http://flybase.net/reports/FBgn0250743.html gene l(3)s113302 16-Dec-15 2015_12 lethal FBgn0020056 E(wa)736 E(wa)736 http://flybase.net/reports/FBgn0020056.html gene E736 16-Dec-15 2015_12 eye color defective pigment cell FBgn0082364 EP569 EP569 http://flybase.net/reports/FBgn0082364.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0262210 mir-927 mir-927 stem loop http://flybase.net/reports/FBgn0262210.html miRNA_gene "dme-mir-927, miR-927, CR42917" CR42917 16-Dec-15 2015_12 "lethal,male,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage" "eye,female,wing,wing margin" FBgn0000334 cml caramel http://flybase.net/reports/FBgn0000334.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0001627 l(1)dn4 lethal (1) discs normal 4 http://flybase.net/reports/FBgn0001627.html gene l(1)d.norm.-4 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028370 kek3 kekkon-3 http://flybase.net/reports/FBgn0028370.html FBgn0027924 protein_coding_gene "0005887=integral component of plasma membrane, 0005886=plasma membrane" "CG4192, BG:DS04862.1, CT12629, kekkon, Kekkon-3" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003591=Leucine-rich repeat, typical subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat" CG4192 16-Dec-15 2015_12 "ENSDARG00000037493(lrrc4c),ENSDARG00000016739(sc:d0316),ENSDARG00000004597,ENSDARG00000014792,ENSDARG00000069402(lrrc4.1),ENSDARG00000003020(LOC566572)" "ENSXETG00000016016(ELFN2),ENSXETG00000022994()" ENSMUSG00000043110(Lrrn4) "ENSG00000173621(LRFN4),ENSG00000156564(LRFN2),ENSG00000126243(LRFN3),ENSG00000165379(LRFN5),ENSG00000128011(LRFN1)" viable FBgn0060506 l(3)S104903a lethal (3) S104903a http://flybase.net/reports/FBgn0060506.html gene 1049/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0013402 anon-14Ba anon-14Ba http://flybase.net/reports/FBgn0013402.html FBgn0014078 gene 16-Dec-15 2015_12 adult stage FBgn0050148 CG30148 http://flybase.net/reports/FBgn0050148.html "FBgn0034516, FBgn0063318" protein_coding_gene "BcDNA:AT18611, CG13429" CG30148 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0031431 CG3515 http://flybase.net/reports/FBgn0031431.html protein_coding_gene "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG3515 16-Dec-15 2015_12 YKL018W(SWD2) viable FBgn0259399 EP-872 http://flybase.net/reports/FBgn0259399.html gene 16-Dec-15 2015_12 visible wing FBgn0283480 Alp2 Alkaline phosphatase 2 http://flybase.net/reports/FBgn0283480.html "FBgn0004474, FBgn0034711" protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "Aph-2, CG3290" "IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase, IPR018299=Alkaline phosphatase, active site, IPR017850=Alkaline-phosphatase-like, core domain" CG3290 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" FBgn0038319 mRpL9 mitochondrial ribosomal protein L9 http://flybase.net/reports/FBgn0038319.html FBgn0051478 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "CG31478, CG4923, L9" "IPR000244=Ribosomal protein L9, IPR009027=Ribosomal protein L9/RNase H1, N-terminal, IPR020070=Ribosomal protein L9, N-terminal" CG31478 16-Dec-15 2015_12 ENSDARG00000063249(mrpl9) WBGene00015025(B0205.11) ENSMUSG00000028140(Mrpl9) ENSG00000143436(MRPL9) "viable,fertile,visible,planar polarity defective" "trichogen cell,tormogen cell" FBgn0021833 l(2)k15819 lethal (2) k15819 http://flybase.net/reports/FBgn0021833.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0035092 Nplp1 Neuropeptide-like precursor 1 http://flybase.net/reports/FBgn0035092.html protein_coding_gene "0048018=receptor agonist activity, 0005184=neuropeptide hormone activity" "0010753=positive regulation of cGMP-mediated signaling, 0007218=neuropeptide signaling pathway" "0005615=extracellular space, 0005576=extracellular region" "NPLP1, MTYamide peptide, IPNa, APK peptide, MTY-amide, MTYamide, neuropeptide-like precursor 1, CG3441, MTYa, Neuropeptide like precursor 1, nplp1, APK, Neuropeptide like precursor protein 1, VQQ, IPNamide, IPNamide peptide, NPLP-1" CG3441 16-Dec-15 2015_12 "viable,fertile" DRSC04370 K -0.125560189 0.05307003 1.217589562 0.567209623 -0.16942877 2.431181704 FBgn0266855 CR45316 http://flybase.net/reports/FBgn0266855.html non_protein_coding_gene lincRNA.321 CR45316 16-Dec-15 2015_12 FBgn0014960 fs(1)A1103 female sterile (1) A1103 http://flybase.net/reports/FBgn0014960.html gene fs(1)1103 16-Dec-15 2015_12 FBgn0065401 l(2)SH1603 lethal (2) SH1603 http://flybase.net/reports/FBgn0065401.html gene l(2)SH2 1603 16-Dec-15 2015_12 "lethal,recessive" FBgn0262520 l(3)psg1 lethal (3) persistent salivary gland 1 http://flybase.net/reports/FBgn0262520.html gene 0043067=regulation of programmed cell death 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during P-stage" embryonic/larval salivary gland FBgn0265635 CR44442 http://flybase.net/reports/FBgn0265635.html non_protein_coding_gene lincRNA.256 CR44442 16-Dec-15 2015_12 FBgn0082948 snoRNA:Me18S-U1356b snoRNA:Me18S-U1356b http://flybase.net/reports/FBgn0082948.html snoRNA_gene "CR34645, Me18S-Um1356b" CR34645 16-Dec-15 2015_12 FBgn0027150 l(3)70Ae lethal (3) 70Ae http://flybase.net/reports/FBgn0027150.html gene Ly-2 16-Dec-15 2015_12 "lethal,recessive" FBgn0045857 e(Pi3K92E)beta e(Pi3K92E)beta http://flybase.net/reports/FBgn0045857.html gene beta 16-Dec-15 2015_12 FBgn0000806 fs(1)de17 female sterile (1) defective eggs 17 http://flybase.net/reports/FBgn0000806.html gene de17 16-Dec-15 2015_12 "female sterile,recessive" "endochorion,dorsal appendage" FBgn0265528 CR44378 http://flybase.net/reports/FBgn0265528.html non_protein_coding_gene lincRNA.326 16-Dec-15 2015_12 FBgn0085451 CG34422 http://flybase.net/reports/FBgn0085451.html "FBgn0030965, FBgn0030967" protein_coding_gene 0003677=DNA binding 0006909=phagocytosis "0070822=Sin3-type complex, 0005634=nucleus" "CG7282, Q9VWP3_DROME, ARID4B, CG7274" "IPR012603=RBB1NT, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR001606=ARID DNA-binding domain, IPR025995=RNA binding activity-knot of a chromodomain" CG34422 16-Dec-15 2015_12 "ENSMUSG00000039219(Arid4b),ENSMUSG00000048118(Arid4a)" "ENSG00000032219(ARID4A),ENSG00000054267(ARID4B)" "visible,viable,partially lethal - majority die" "wing,trichogen cell" DRSC20031 IE -2.046217144 0.653269786 -1.990817488 0.187659604 0.774209984 1.443258322 FBgn0260335 GSd452 http://flybase.net/reports/FBgn0260335.html gene 16-Dec-15 2015_12 lethal FBgn0029834 CG5937 http://flybase.net/reports/FBgn0029834.html protein_coding_gene 0005086=ARF guanyl-nucleotide exchange factor activity "0016192=vesicle-mediated transport, 0032012=regulation of ARF protein signal transduction" 0005802=trans-Golgi network "IPR016024=Armadillo-type fold, IPR015403=Domain of unknown function DUF1981, Sec7 associated, IPR000904=Sec7 domain" CG5937 16-Dec-15 2015_12 ENSXETG00000010774(KIAA1244) ENSMUSG00000019852(D10Bwg1379e) ENSG00000112379(KIAA1244) "viable,visible" "chaeta,supernumerary" FBgn0039590 CG10011 http://flybase.net/reports/FBgn0039590.html protein_coding_gene "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG10011 16-Dec-15 2015_12 ENSXETG00000022980(ANKRD50) ENSG00000151458(ANKRD50) "viable,fertile" FBgn0262981 CR43289 http://flybase.net/reports/FBgn0262981.html non_protein_coding_gene CG43289 CR43289 16-Dec-15 2015_12 FBgn0015466 l(2)44Fa lethal (2) 44Fa http://flybase.net/reports/FBgn0015466.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive" FBgn0262513 Vha16-4 Vacuolar H+ ATPase 16kD subunit 4 http://flybase.net/reports/FBgn0262513.html "FBgn0028666, FBgn0034169" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0015078=hydrogen ion transmembrane transporter activity" "0015991=ATP hydrolysis coupled proton transport, 0015992=proton transport" "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "Vacuolar H[+] ATPase subunit 16-4, vha16-4, CG9013, Vha16-4" "IPR002379=V-ATPase proteolipid subunit C-like domain, IPR000245=V-ATPase proteolipid subunit, IPR011555=V-ATPase proteolipid subunit C, eukaryotic" CG9013 16-Dec-15 2015_12 FBgn0001803 l(1)Mc28 lethal (1) Mc28 http://flybase.net/reports/FBgn0001803.html gene 16-Dec-15 2015_12 "lethal,recessive" "macrochaeta,somatic clone,wing hair" FBgn0060556 l(3)S097406b lethal (3) S097406b http://flybase.net/reports/FBgn0060556.html gene 0974/06 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0066318 26D19 26D19 http://flybase.net/reports/FBgn0066318.html gene 0016319=mushroom body development 16-Dec-15 2015_12 "embryonic/larval mushroom body,somatic clone" FBgn0043019 ttk::Hsap\BCL6 BCL6 http://flybase.net/reports/FBgn0043019.html engineered_fusion_gene 16-Dec-15 2015_12 visible "eye,ommatidium,photoreceptor cell R7,eye photoreceptor cell" FBgn0260589 2L3189 http://flybase.net/reports/FBgn0260589.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0004016 wk weak http://flybase.net/reports/FBgn0004016.html gene 16-Dec-15 2015_12 "viable,reduced" "wing,abdomen,macrochaeta" FBgn0051026 CR31026 http://flybase.net/reports/FBgn0051026.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0027506 EDTP Egg-derived tyrosine phosphatase http://flybase.net/reports/FBgn0027506.html FBgn0062229 protein_coding_gene 0004725=protein tyrosine phosphatase activity "0016311=dephosphorylation, 0048477=oogenesis, 0006470=protein dephosphorylation" "BcDNA:LD23181, CG6542, D-EDTP, anon-WO0118547.124" "IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site, IPR010569=Myotubularin-like phosphatase domain" CG6542 16-Dec-15 2015_12 ENSDARG00000059642(mtmr14) ENSXETG00000017860(MTMR14) ENSMUSG00000030269(Mtmr14) ENSG00000163719(MTMR14) "viable,fertile,lethal,recessive,some die during embryonic stage" "ovary,germline clone" FBgn0013685 mt:ND6 mitochondrial NADH-ubiquinone oxidoreductase chain 6 http://flybase.net/reports/FBgn0013685.html FBgn0002867 protein_coding_gene 0008137=NADH dehydrogenase (ubiquinone) activity 0055114=oxidation-reduction process "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "nd6, CG34089, URF6, nad6, ND6" "IPR001457=NADH:ubiquinone/plastoquinone oxidoreductase, chain 6" CG34089 16-Dec-15 2015_12 FBgn0000284 cf cleft http://flybase.net/reports/FBgn0000284.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile" "wing,crossvein,wing vein L4" FBgn0003897 tur turnip http://flybase.net/reports/FBgn0003897.html gene 0008355=olfactory learning 16-Dec-15 2015_12 "learning defective,memory defective" FBgn0264994 CR44145 http://flybase.net/reports/FBgn0264994.html non_protein_coding_gene CR44145 16-Dec-15 2015_12 FBgn0060796 l(3)S058004b lethal (3) S058004b http://flybase.net/reports/FBgn0060796.html gene 0580/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0029531 CG13362 http://flybase.net/reports/FBgn0029531.html protein_coding_gene CG13362 16-Dec-15 2015_12 viable FBgn0015938 fits fades in the stretch http://flybase.net/reports/FBgn0015938.html gene 16-Dec-15 2015_12 FBgn0262116 RNASEK Ribonuclease kappa http://flybase.net/reports/FBgn0262116.html "FBgn0058127, FBan0040127, FBgn0027746, FBgn0063194, FBgn0067378" protein_coding_gene 0004521=endoribonuclease activity "0098586=cellular response to virus, 0009303=rRNA transcription" "ribonuclease kappa, l(2)NC110, BcDNA:GM16138, dRNASEK, NC110, GM16138, lethal (2) NC110, anon-EST:Posey156, CG40127" IPR026770=Ribonuclease kappa CG40127 16-Dec-15 2015_12 "ENSDARG00000069461(rnaseka),ENSDARG00000069336(rnasekb)" WBGene00009881(F49C12.12) ENSXETG00000017228(RNASEK) ENSMUSG00000040904(Rnasek) ENSG00000219200(RNASEK) "lethal,recessive" DRSC21641 IE -0.292381395 -1.824657266 -0.246721731 -1.78561779 -0.538696196 0.000388191 FBgn0266932 CR45383 http://flybase.net/reports/FBgn0266932.html non_protein_coding_gene CR45383 16-Dec-15 2015_12 FBgn0040616 CG12871 http://flybase.net/reports/FBgn0040616.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040363 CG11384 http://flybase.net/reports/FBgn0040363.html FBgn0029562 protein_coding_gene EG:BACR42I17.3 IPR008166=Glycosyltransferase family 92 CG11384 16-Dec-15 2015_12 ENSDARG00000053345(LOC100334791) WBGene00012941(Y47D3B.4) "ENSXETG00000026707(),ENSXETG00000026391()" FBgn0038281 RpL10Aa Ribosomal protein L10Aa http://flybase.net/reports/FBgn0038281.html FBgn0063342 protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" "0006412=translation, 0006909=phagocytosis, 0022008=neurogenesis" 0022625=cytosolic large ribosomal subunit "Rpl10Aa, BcDNA:AT11516, CG3843" "IPR023674=Ribosomal protein L1-like, IPR016094=Ribosomal protein L1, 2-layer alpha/beta-sandwich, IPR002143=Ribosomal protein L1, IPR016095=Ribosomal protein L1, 3-layer alpha/beta-sandwich, IPR028364=Ribosomal protein L1/ribosomal biogenesis protein" CG3843 16-Dec-15 2015_12 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC15518 EK -0.513803554 -1.207790896 0.325754437 -1.5958244 0.55805702 1.646782289 FBgn0002339 l(3)87Bh lethal (3) 87Bh http://flybase.net/reports/FBgn0002339.html gene "l(3)ck20, ck20" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0053159 CG33159 http://flybase.net/reports/FBgn0053159.html FBgn0035417 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP176, CG11532" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG33159 16-Dec-15 2015_12 FBgn0036899 tey teyrha-meyrha http://flybase.net/reports/FBgn0036899.html protein_coding_gene "0045892=negative regulation of transcription, DNA-templated, 0008039=synaptic target recognition" 0005634=nucleus "CG8780, teyrha-meyhra, teyrha meyrha" CG8780 16-Dec-15 2015_12 "visible,lethal,neuroanatomy defective,viable" "costal cell,distal costal vein,medial costal vein,wing vein,ectopic,eye,abdominal segment motor neuron,A1-7 ventral longitudinal muscle 1" FBgn0001853 l(1)tsUC19 lethal (1) tsUC19 http://flybase.net/reports/FBgn0001853.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0039369 CG17195 http://flybase.net/reports/FBgn0039369.html protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0008270=zinc ion binding" 0018345=protein palmitoylation 0005783=endoplasmic reticulum CG17195-PA "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG17195 16-Dec-15 2015_12 YOL003C(PFA4) WBGene00008606(dhhc-1) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) "partially lethal - majority die,some die during pupal stage" FBgn0040121 l(2)23Dc lethal (2) 23Dc http://flybase.net/reports/FBgn0040121.html gene l(2)23Ca 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0058250 CG40250 http://flybase.net/reports/FBgn0058250.html protein_coding_gene 16-Dec-15 2015_12 FBgn0030301 HP5 Heterochromatin protein 5 http://flybase.net/reports/FBgn0030301.html protein_coding_gene 0010369=chromocenter CG1745 CG1745 16-Dec-15 2015_12 "viable,fertile,suppressor of variegation,dominant" FBgn0000219 bright bright http://flybase.net/reports/FBgn0000219.html gene bri 16-Dec-15 2015_12 "visible,recessive,eye color defective" "eye,pigment cell,Malpighian tubule" FBgn0038851 dmrt93B doublesex-Mab related 93B http://flybase.net/reports/FBgn0038851.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "unnamed, dmrt93b, CG5737" "IPR001275=DM DNA-binding domain, IPR026607=DMRT/protein doublesex/protein male abnormal 3, IPR005173=DMRTA motif" CG5737 16-Dec-15 2015_12 ENSDARG00000039412(dmrta2) WBGene00007776(dmd-4) ENSG00000176399(DMRTA1) viable FBgn0022960 vimar visceral mesodermal armadillo-repeats http://flybase.net/reports/FBgn0022960.html "FBgn0021806, FBgn0027729" protein_coding_gene 0017160=Ral GTPase binding "0042052=rhabdomere development, 1901216=positive regulation of neuron death, 0006099=tricarboxylic acid cycle, 0046716=muscle cell cellular homeostasis" 0005886=plasma membrane "visceral mesoderm armadillo repeats, l(2)k16722, Visceral mesodermal armadillo repeats, CG3572, Visceral mesodermal armadillo-repeats, Vimar, anon-EST:Posey213" "IPR000225=Armadillo, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG3572 16-Dec-15 2015_12 "ENSDARG00000056080,ENSDARG00000013046" ENSXETG00000007529(RAP1GDS1) ENSMUSG00000028149(Rap1gds1) ENSG00000138698(RAP1GDS1) " embryonic stage | stage 1-4 , larval stage | first instar , embryonic stage--larval stage , adult stage | female , embryonic stage | stage 9-17 " organism

"viable,fertile,lethal,recessive" FBgn0000300 cgd congested http://flybase.net/reports/FBgn0000300.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,embryonic/larval midgut" FBgn0039053 CG6738 http://flybase.net/reports/FBgn0039053.html protein_coding_gene 0004046=aminoacylase activity 0006520=cellular amino acid metabolic process 0005737=cytoplasm "IPR002933=Peptidase M20, IPR010159=N-acyl-L-amino-acid amidohydrolase, IPR011650=Peptidase M20, dimerisation domain" CG6738 16-Dec-15 2015_12 "ENSDARG00000004845(LOC100001620),ENSDARG00000038475(zgc:55605)" "WBGene00007507(C10C5.3),WBGene00007508(C10C5.4),WBGene00007509(C10C5.5),WBGene00015509(C06A6.4)" ENSXETG00000000089(acy1) ENSMUSG00000023262(Acy1) ENSG00000114786(ACY1) viable FBgn0005741 l(1)TK233 lethal (1) TK233 http://flybase.net/reports/FBgn0005741.html gene l233 16-Dec-15 2015_12 lethal FBgn0065394 l(2)SH1622 lethal (2) SH1622 http://flybase.net/reports/FBgn0065394.html gene l(2)SH2 1622 16-Dec-15 2015_12 "lethal,recessive" FBgn0010097 ë_Tub37C ë_-Tubulin at 37C http://flybase.net/reports/FBgn0010097.html FBgn0001003 protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005525=GTP binding, 0003924=GTPase activity" "0007020=microtubule nucleation, 0031122=cytoplasmic microtubule organization, 0051663=oocyte nucleus localization involved in oocyte dorsal/ventral axis specification, 0007017=microtubule-based process, 0007057=spindle assembly involved in female meiosis I, 0051316=attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation" "0005819=spindle, 0005813=centrosome, 0072687=meiotic spindle, 0005874=microtubule, 0005875=microtubule associated complex, 0005815=microtubule organizing center, 0005737=cytoplasm, 0008275=gamma-tubulin small complex, 0045298=tubulin complex" "gamma-tubulin, D.m.GAMMA-37C, gamma-tubulin (37C), CG17566, TW1, gamma-tub37CD, GTU88*, gamma-Tub37C, gammaTub2, Gamma Tubulin at 37C, gamma-Tubulin, gamma Tubulin2, gammatub, female sterile(2)Ted Wright 1, fsTW1, g-Tubulin, gamma-tub37C, tubulin, gammaTub, gammaTub37CD, gamma Tub37CD, fs(2)TW1, gammaTub37C, gamma tubulin, gamma-tubulin-2, gamma-tubulin37C, gammaTUB, PL10, gammaTub37c, gammaTubulin, gama-tubulin, gamma[mat], maternal gamma-tubulin, gamma-Tub, gammaTUB37C, gammatubulin, fs(2)TWI, Rb1011, 37CD gamma-tubulin" "IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR000217=Tubulin, IPR003008=Tubulin/FtsZ, GTPase domain, IPR002454=Gamma tubulin, IPR023123=Tubulin, C-terminal, IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal" CG17566 16-Dec-15 2015_12 ENSDARG00000015610(tubgl) YLR212C(TUB4) WBGene00006540(tbg-1) ENSXETG00000014898() "ENSMUSG00000035198(Tubg1),ENSMUSG00000045007(Tubg2)" "ENSG00000131462(TUBG1),ENSG00000037042(TUBG2)" "female sterile,recessive,male fertile,meiotic cell cycle defective,wild-type,mitotic cell cycle defective,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,viable" "condensed nuclear chromosome,meiotic spindle,oocyte nucleus,meiotic metaphase I,cleavage stage embryo,spindle,centrosome | maternal effectTE37C-7),polar body nucleus,oocyte,nucleus,spindle & oocyte,egg & spindleTE37C-7),condensed nuclear chromosomeExel6043),meiotic spindleExel6043),spindle | cleavage stage | maternal effect,spindle | embryonic stage,aster | embryonic stage,embryo & mitosis & nuclear chromosome,maternal effect,spindle | maternal effectTE37C-7),ovariole,germline clone" FBgn0065681 l(2)SH0664 lethal (2) SH0664 http://flybase.net/reports/FBgn0065681.html gene l(2)SH2 0664 16-Dec-15 2015_12 "lethal,recessive" FBgn0022747 anon-E9 anon-E9 http://flybase.net/reports/FBgn0022747.html gene E9 16-Dec-15 2015_12 FBgn0003115 plw pale wing http://flybase.net/reports/FBgn0003115.html gene 16-Dec-15 2015_12 "viable,poor,body color defective" "wing,macrochaeta" FBgn0004148 l(2)57Ab lethal (2) 57Ab http://flybase.net/reports/FBgn0004148.html gene 16-Dec-15 2015_12 "lethal,visible,recessive" FBgn0283437 PPO1 Prophenoloxidase 1 http://flybase.net/reports/FBgn0283437.html "FBgn0261362, FBgn0003081, FBgn0004627, FBgn0000165, FBgn0261382" protein_coding_gene "0036264=dopamine monooxygenase activity, 0036263=L-DOPA monooxygenase activity, 0004097=catechol oxidase activity, 0004503=monophenol monooxygenase activity" "0050830=defense response to Gram-positive bacterium, 0035314=scab formation, 0042417=dopamine metabolic process, 0042381=hemolymph coagulation, 0042060=wound healing, 0035006=melanization defense response, 0035011=melanotic encapsulation of foreign target, 0009611=response to wounding, 0050832=defense response to fungus" 0005576=extracellular region "Monophenoloxidase, ProPO A1, ProPO54, CG42639, pro-phenol oxidase A1, Mox, bc, pro-PO, CG5779, Phox, Bc, proPO-A1, ProPO, A1, prophenol oxidase A1, Monophenol oxidase, PO54, DmePPOA1, PPO, Black Cell, phenoloxidase, i12, PO, A[[1]], PO A1, Black cells, Prophenoloxidase, Diphenol oxidase A1 subunit, Black cell, Prophenoloxidase A1, black cells, Dox-A1, pro-POA[[1]], proPO, proPO A[[1]], DoxA1, pro-A, ProPo, Propo, prophenoloxidase A[[1]], proPO54, prophenoloxidase" "IPR002227=Tyrosinase copper-binding domain, IPR014756=Immunoglobulin E-set, IPR000896=Hemocyanin/hexamerin middle domain, IPR005203=Hemocyanin, C-terminal, IPR005204=Hemocyanin, N-terminal, IPR013788=Hemocyanin/hexamerin, IPR008922=Uncharacterised domain, di-copper centre" CG42639 16-Dec-15 2015_12 FBgn0087041 CG42231 http://flybase.net/reports/FBgn0087041.html protein_coding_gene CG42231 16-Dec-15 2015_12 FBgn0054049 CG34049 http://flybase.net/reports/FBgn0054049.html FBgn0082841 protein_coding_gene 0005576=extracellular region "unnamed, BP1065" "IPR018244=Allergen V5/Tpx-1-related, conserved site, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG34049 16-Dec-15 2015_12 FBgn0259378 C865 http://flybase.net/reports/FBgn0259378.html gene 16-Dec-15 2015_12 visible wing vein FBgn0264841 CR44049 http://flybase.net/reports/FBgn0264841.html non_protein_coding_gene CR44049 16-Dec-15 2015_12 FBgn0263385 CR43437 http://flybase.net/reports/FBgn0263385.html non_protein_coding_gene CR43437 16-Dec-15 2015_12 FBgn0267863 CR46151 http://flybase.net/reports/FBgn0267863.html pseudogene_attribute CR46151 16-Dec-15 2015_12 FBgn0051119 HDAC11 Histone deacetylase 11 http://flybase.net/reports/FBgn0051119.html protein_coding_gene 0004407=histone deacetylase activity 0016575=histone deacetylation 0000118=histone deacetylase complex "HDAC11, dmHDA403, HdacX, CG31119, HDACX, dHDAC11, Histone deacetylase X, DHDACX, Hdac11" "IPR023801=Histone deacetylase domain, IPR000286=Histone deacetylase superfamily" CG31119 16-Dec-15 2015_12 ENSDARG00000037346(zgc:91942) WBGene00007953(hdac-11) ENSMUSG00000034245(Hdac11) ENSG00000163517(HDAC11) FBgn0020893 Su(osk)K2 Suppressor of oskar K2 http://flybase.net/reports/FBgn0020893.html gene K2 16-Dec-15 2015_12 FBgn0002628 M(3)100CF Minute (3) 100CF http://flybase.net/reports/FBgn0002628.html gene "unnamed, M(3)f" 16-Dec-15 2015_12 "female sterile,Minute,dominant,visible" macrochaeta FBgn0260347 GSd456 http://flybase.net/reports/FBgn0260347.html gene 16-Dec-15 2015_12 lethal FBgn0000703 fltI flight defective I http://flybase.net/reports/FBgn0000703.html gene 16-Dec-15 2015_12 flight defective FBgn0051128 CG31128 http://flybase.net/reports/FBgn0051128.html FBgn0063761 protein_coding_gene BcDNA:AT04449 CG31128 16-Dec-15 2015_12 viable DRSC13675 K 0.643136191 0.129282895 0.031972839 0.647969477 5.545474686 0.590315916 FBgn0261356 CG42633 http://flybase.net/reports/FBgn0261356.html FBgn0037833 protein_coding_gene CG6547 CG42633 16-Dec-15 2015_12 DRSC16061 K 0.202706458 0.381547892 1.011542126 -0.114301083 0.588897376 -1.708518502 FBgn0266419 CR45059 http://flybase.net/reports/FBgn0266419.html non_protein_coding_gene CR45059 16-Dec-15 2015_12 FBgn0035578 CG13707 http://flybase.net/reports/FBgn0035578.html protein_coding_gene CG13707 16-Dec-15 2015_12 viable FBgn0051231 CG31231 http://flybase.net/reports/FBgn0051231.html "FBgn0044533, FBgn0047317, FBgn0065003" protein_coding_gene "anon-WO0140519.92, BcDNA:GH08511, BcDNA:AT20662" IPR025254=Domain of unknown function DUF4201 CG31231 16-Dec-15 2015_12 ENSMUSG00000050677(Ccdc96) "partially lethal - majority die,some die during pupal stage" FBgn0267304 CR45740 http://flybase.net/reports/FBgn0267304.html non_protein_coding_gene CR45740 16-Dec-15 2015_12 FBgn0024228 hopR-90E hop-responsive-90E http://flybase.net/reports/FBgn0024228.html gene unnamed 16-Dec-15 2015_12 FBgn0011161 l(1)Q240 lethal (1) Q240 http://flybase.net/reports/FBgn0011161.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0031713 CG7277 http://flybase.net/reports/FBgn0031713.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016709=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" "0055114=oxidation-reduction process, 0006744=ubiquinone biosynthetic process" "IPR000689=Ubiquinone biosynthesis monooxygenase COQ6, IPR010971=Ubiquinone biosynthesis hydroxylase UbiH/COQ6, IPR018168=Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site, IPR002938=FAD-binding domain" CG7277 16-Dec-15 2015_12 ENSDARG00000060380(coq6) YGR255C(COQ6) WBGene00000766(coq-6) ENSXETG00000002853(coq6) ENSMUSG00000021235(Coq6) ENSG00000119723(COQ6) viable FBgn0033927 CR10102 http://flybase.net/reports/FBgn0033927.html pseudogene_attribute "Arc3, dArc3, CG10102" CR10102 16-Dec-15 2015_12 "viable,fertile,hyperactive,conditional,chemical resistant" DRSC05963 I -0.693321263 -1.649586046 -0.156981717 -0.806360034 -0.613843433 0.264347466 FBgn0032822 CG10466 http://flybase.net/reports/FBgn0032822.html FBgn0044613 protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" "cg10466, anon-WO0140519.255" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10466 16-Dec-15 2015_12 YIR005W(IST3) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0043482 l(3)66EFd lethal (3) 66EFd http://flybase.net/reports/FBgn0043482.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263630 mir-3641 mir-3641 stem loop http://flybase.net/reports/FBgn0263630.html "FBgn0262136, FBgn0263535" miRNA_gene CR43520 CR43520 16-Dec-15 2015_12 FBgn0002126 l(2)IIJ59 lethal (2) IIJ59 http://flybase.net/reports/FBgn0002126.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0019775 l(1)36 lethal (1) 36 http://flybase.net/reports/FBgn0019775.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267293 CR45729 http://flybase.net/reports/FBgn0267293.html non_protein_coding_gene CR45729 16-Dec-15 2015_12 FBgn0004555 mosaic-wings mosaic wings http://flybase.net/reports/FBgn0004555.html gene mow 16-Dec-15 2015_12 "visible,recessive" wing FBgn0002917 na narrow abdomen http://flybase.net/reports/FBgn0002917.html "FBgn0004144, FBgn0030560" protein_coding_gene "0005216=ion channel activity, 0005261=cation channel activity, 0005245=voltage-gated calcium channel activity" "0042752=regulation of circadian rhythm, 0006811=ion transport, 0072347=response to anesthetic, 0055085=transmembrane transport, 0022008=neurogenesis, 0007623=circadian rhythm, 0035176=social behavior, 0050975=sensory perception of touch, 0008344=adult locomotory behavior, 0048512=circadian behavior, 0045475=locomotor rhythm" "0016020=membrane, 0043679=axon terminus, 0043025=neuronal cell body" "CG1517, har, Dmalpha1U, har 38, Dma1U, har85, har 85, harA, Na, NARROW ABDOMEN, alpha1U, NALCN, har38, NA, halothane-resistant" "IPR028823=Sodium leak channel non-selective protein, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR005821=Ion transport domain" CG1517 16-Dec-15 2015_12 ENSDARG00000001835(nalcn) "WBGene00003558(nca-2),WBGene00003557" ENSMUSG00000000197(Nalcn) ENSG00000102452(NALCN) adult stage " supraesophageal ganglion

subset , optic lobe

subset , ellipsoid body

subset " "viable,fertile,chemical sensitive,locomotor behavior defective,locomotor rhythm defective,circadian behavior defective,wild-type,chemical resistant,recessive,gravitaxis defective,visible,behavior defective,lethal,partially,partially lethal - majority die,some die during pupal stage,flight defective,neuroanatomy defective,touch sensitivity defective" "adult abdomen,adult head,wing,thorax,mesothoracic tergum,ganglion mother cell,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0004438 prd1 paired-like 1 http://flybase.net/reports/FBgn0004438.html gene PRD gene 1 16-Dec-15 2015_12 " embryonic stage | <8-12 hr , oogenesis stage " FBgn0259945 Ttd11 TRPL translocation defect 11 http://flybase.net/reports/FBgn0259945.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019759 l(1)75B1 lethal (1) 75B1 http://flybase.net/reports/FBgn0019759.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263741 CG43666 http://flybase.net/reports/FBgn0263741.html FBgn0034550 protein_coding_gene 0016020=membrane CG15226 IPR002000=Lysosome-associated membrane glycoprotein CG43666 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pharate adult stage" trichogen cell FBgn0039889 Arl4 ADP ribosylation factor-like 4 http://flybase.net/reports/FBgn0039889.html FBgn0063303 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0007264=small GTPase mediated signal transduction 0005622=intracellular "CG 2219, BcDNA:AT26185, Q9V4B2, CG2219, Arl4, ARL4B" "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR024156=Small GTPase superfamily, ARF type" CG2219 16-Dec-15 2015_12 "ENSDARG00000032708(arl4cb),ENSDARG00000057606(arl4ca),ENSDARG00000033182(arl4l)" "ENSXETG00000010915(arl7),ENSXETG00000011342(arl4a)" "ENSMUSG00000049866(Arl4c),ENSMUSG00000047446(Arl4a)" "ENSG00000188042(ARL4C),ENSG00000122644(ARL4A)" viable FBgn0264675 CR43960 http://flybase.net/reports/FBgn0264675.html non_protein_coding_gene CR43960 16-Dec-15 2015_12 FBgn0069238 gl(1)170-20 gl(1)170-20 http://flybase.net/reports/FBgn0069238.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "viable,terminal phenotype,germline clone,maternal effect" "filzkorper,germline clone,maternal effect,embryo" FBgn0082637 S(CycEJP)13S1 S(CycEJP)13S1 http://flybase.net/reports/FBgn0082637.html gene 13S1 16-Dec-15 2015_12 "lethal,recessive" FBgn0030090 fend forked end http://flybase.net/reports/FBgn0030090.html FBgn0062929 protein_coding_gene 0008045=motor neuron axon guidance 0005886=plasma membrane "Dromel_CG12664_FBtr0071349_ld14_mORF, BcDNA:RH56795, LD14, CG12664, ld14, fend, forked end, Forked end" CG12664 16-Dec-15 2015_12 "neuroanatomy defective,viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" "motor neuron | third instar larval stage,intersegmental nerve | third instar larval stage,embryonic/larval neuromuscular junction,ectopic,intersegmental nerve,mesothoracic tergum" FBgn0043866 palido palido http://flybase.net/reports/FBgn0043866.html gene 0007346=regulation of mitotic cell cycle 16-Dec-15 2015_12 FBgn0026341 Su(tor)2-164-14 Su(tor)2-164-14 http://flybase.net/reports/FBgn0026341.html gene 16-Dec-15 2015_12 FBgn0033916 Usp20-33 Ubiquitin specific protease 20/33 http://flybase.net/reports/FBgn0033916.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0007399=nervous system development" "Usp20, USP20, CG8494, Usp33, Q7JW61" "IPR028889=Ubiquitin specific protease domain, IPR018200=Ubiquitin specific protease, conserved site, IPR006615=Peptidase C19, ubiquitin-specific peptidase, DUSP domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG8494 16-Dec-15 2015_12 "ENSDARG00000016163(usp33),ENSDARG00000027501(usp20)" "ENSXETG00000013118(usp33),ENSXETG00000012844(USP20)" "ENSMUSG00000026854(Usp20),ENSMUSG00000025437(Usp33)" "ENSG00000136878(USP20),ENSG00000077254(USP33)" "viable,short lived,locomotor behavior defective" FBgn0015961 l(2)46Co lethal (2) 46Co http://flybase.net/reports/FBgn0015961.html gene group 3 16-Dec-15 2015_12 "lethal,recessive" FBgn0029976 snz snazarus http://flybase.net/reports/FBgn0029976.html protein_coding_gene "0035091=phosphatidylinositol binding, 0005543=phospholipid binding" "0038032=termination of G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan" 0016020=membrane "CG1514, DmSNX25, Snz" "IPR003114=Phox-associated domain, IPR016137=RGS domain, IPR001683=Phox homologous domain, IPR013937=Sorting nexin, C-terminal" CG1514 16-Dec-15 2015_12 ENSDARG00000013828 YML104C(MDM1) WBGene00013803(Y116A8C.26) ENSXETG00000022783(SNX13) ENSMUSG00000038291(Snx25) ENSG00000109762(SNX25) "long lived,recessive,fertile,female fertile,viable,maternal effect" FBgn0060585 l(3)S094105b lethal (3) S094105b http://flybase.net/reports/FBgn0060585.html gene 0941/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0015429 l(1)2BCa lethal (1) 2BCa http://flybase.net/reports/FBgn0015429.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0038509 CG14332 http://flybase.net/reports/FBgn0038509.html protein_coding_gene CG14332 16-Dec-15 2015_12 viable FBgn0034902 CG5532 http://flybase.net/reports/FBgn0034902.html protein_coding_gene 0016020=membrane "IPR005349=Uncharacterised protein family UPF0136, Transmembrane" CG5532 16-Dec-15 2015_12 ENSDARG00000070232(zgc:163080) YJR085C() "ENSXETG00000001071(),ENSXETG00000015964(TMEM14A)" ENSMUSG00000021361(Tmem14c) "ENSG00000111843(TMEM14C),ENSG00000137210(TMEM14B)" viable FBgn0030502 tth toothrin http://flybase.net/reports/FBgn0030502.html FBgn0025209 protein_coding_gene 0006909=phagocytosis "anon-EST:fe2G7, anon-fast-evolving-2G7, CG12175, toothreen" IPR025750=Requiem/DPF N-terminal domain CG12175 16-Dec-15 2015_12 "viable,body color defective,visible,partially lethal - majority die,some die during pupal stage" "mesothoracic tergum,trichogen cell" FBgn0050417 tbrd-3 testis-specifically expressed bromodomain containing protein-3 http://flybase.net/reports/FBgn0050417.html FBgn0034845 protein_coding_gene "0005694=chromosome, 0005730=nucleolus" "CG17692, tBRD-3, CG30417" "IPR027353=NET domain, IPR001487=Bromodomain" CG30417 16-Dec-15 2015_12 WBGene00017423(F13C5.2) "viable,visible" trichogen cell FBgn0037686 RpL34b Ribosomal protein L34b http://flybase.net/reports/FBgn0037686.html "FBgn0025253, FBgn0025263" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "anon-fast-evolving-1E8, unnamed, anon-fast-evolving-1C10, anon-EST:fe1C10, RpL34b, L34b, Rp L34b, CG9354, RpL34, anon-EST:fe1E8" "IPR018065=Ribosomal protein L34e, conserved site, IPR008195=Ribosomal protein L34Ae" CG9354 16-Dec-15 2015_12 ENSDARG00000029500(rpl34) "YIL052C(RPL34B),YER056C-A(RPL34A)" WBGene00004448(rpl-34) "ENSXETG00000021095(rpl34a),ENSXETG00000020482()" "ENSMUSG00000062006(Rpl34),ENSMUSG00000066116(Gm10154),ENSMUSG00000060730(Gm10086),ENSMUSG00000061669(Gm6404),ENSMUSG00000078128(Gm2178)" ENSG00000109475(RPL34) viable DRSC16475 IK -1.761711107 -0.148091675 0.095935249 -0.014494017 -1.8112065 -0.499384114 FBgn0014888 Su(phl)7 Suppressor of pole hole 7 http://flybase.net/reports/FBgn0014888.html gene "Suppressor of raf-like-oncogene, Su(D-raf)7" 16-Dec-15 2015_12 FBgn0000759 fs(1)A473 female sterile (1) A473 http://flybase.net/reports/FBgn0000759.html gene fs(1)473 16-Dec-15 2015_12 "female sterile soma-dependent,recessive" egg FBgn0039872 salt salty dog http://flybase.net/reports/FBgn0039872.html protein_coding_gene 0008507=sodium:iodide symporter activity 0055085=transmembrane transport 0016323=basolateral plasma membrane "CG2196, dSLC5A7, salty" "IPR001734=Sodium/solute symporter, IPR019900=Sodium/solute symporter, subgroup" CG2196 16-Dec-15 2015_12 YHL016C(DUR3) "stress response defective,viable" FBgn0267923 CR46204 http://flybase.net/reports/FBgn0267923.html non_protein_coding_gene lincRNA.172 CR46204 16-Dec-15 2015_12 FBgn0044128 E(rst)A5 E(rst)A5 http://flybase.net/reports/FBgn0044128.html gene 0001745=compound eye morphogenesis A5 16-Dec-15 2015_12 viable FBgn0263665 CR43656 http://flybase.net/reports/FBgn0263665.html non_protein_coding_gene CR43656 16-Dec-15 2015_12 FBgn0060510 l(3)S104210a lethal (3) S104210a http://flybase.net/reports/FBgn0060510.html gene 1042/10 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0020894 Su(osk)H1 Suppressor of oskar H1 http://flybase.net/reports/FBgn0020894.html gene H1 16-Dec-15 2015_12 FBgn0266981 CR45432 http://flybase.net/reports/FBgn0266981.html non_protein_coding_gene CR45432 16-Dec-15 2015_12 FBgn0050430 CG30430 http://flybase.net/reports/FBgn0050430.html "FBgn0045148, FBgn0045163, FBgn0045263, FBgn0045290, FBgn0045293, FBgn0045301, FBgn0045316, FBgn0045322, FBgn0045414, FBgn0045425, FBgn0045435" protein_coding_gene "NEST:bs13e09, NEST:bs15d07, NEST:bs01g11, NEST:bs29b02, NEST:bs12g08, NEST:bs04a11, NEST:bs27g03, NEST:bs14e02, NEST:bs02g04, NEST:bs15a10, NEST:bs17g03" CG30430 16-Dec-15 2015_12 viable FBgn0014951 bwl bow-legged http://flybase.net/reports/FBgn0014951.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,poor" "wing,femur,tibia,macrochaeta,leg" FBgn0266725 CR45198 http://flybase.net/reports/FBgn0266725.html non_protein_coding_gene CR45198 16-Dec-15 2015_12 FBgn0000794 fs(1)de5 female sterile (1) defective eggs 5 http://flybase.net/reports/FBgn0000794.html gene de5 16-Dec-15 2015_12 female sterile "endochorion,dorsal appendage,chorion" FBgn0267877 CR46165 http://flybase.net/reports/FBgn0267877.html pseudogene_attribute CG12717-related CR46165 16-Dec-15 2015_12 FBgn0040120 l(2)23Dd lethal (2) 23Dd http://flybase.net/reports/FBgn0040120.html gene l(2)23Cb 16-Dec-15 2015_12 "lethal,recessive" FBgn0065150 l(3)SH070 lethal (3) SH070 http://flybase.net/reports/FBgn0065150.html gene l(2)SH3 070 16-Dec-15 2015_12 "lethal,recessive" FBgn0261737 EC3959 http://flybase.net/reports/FBgn0261737.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0031966 CG14532 http://flybase.net/reports/FBgn0031966.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065122 l(3)SH145 lethal (3) SH145 http://flybase.net/reports/FBgn0065122.html gene l(2)SH3 145 16-Dec-15 2015_12 "lethal,recessive" FBgn0058279 CG40279 http://flybase.net/reports/FBgn0058279.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266487 CG45086 http://flybase.net/reports/FBgn0266487.html protein_coding_gene Dromel_CG17759_galpha49b_uORF CG45086 16-Dec-15 2015_12 FBgn0043580 MESK3 Misexpression Suppressor of KDN 3 http://flybase.net/reports/FBgn0043580.html gene 0046579=positive regulation of Ras protein signal transduction 16-Dec-15 2015_12 viable FBgn0036787 CG4306 http://flybase.net/reports/FBgn0036787.html protein_coding_gene 0003839=gamma-glutamylcyclotransferase activity "0042381=hemolymph coagulation, 0006750=glutathione biosynthetic process" 0005576=extracellular region "IPR013024=Butirosin biosynthesis, BtrG-like, IPR017939=Gamma-glutamylcyclotransferase" CG4306 16-Dec-15 2015_12 ENSDARG00000005085(ggct) WBGene00016629(C44B7.7) ENSXETG00000022014(TEgg096f01.1) ENSMUSG00000002797(Ggct) ENSG00000006625(GGCT) FBgn0032876 Cen Centrocortin http://flybase.net/reports/FBgn0032876.html protein_coding_gene 0005515=protein binding 0040016=embryonic cleavage "0032154=cleavage furrow, 0005813=centrosome" "CG1962, cen, centrocortin, 38E.1" IPR026079=Cerebellar degeneration-related protein 2 CG1962 16-Dec-15 2015_12 "ENSDARG00000026834(zgc:77462),ENSDARG00000035952,ENSDARG00000037359" "ENSXETG00000016662(Q6GL55_XENTR),ENSXETG00000012504(CDR2L)" "ENSMUSG00000030878(Cdr2),ENSMUSG00000050910(Cdr2l)" "viable,fertile,partially lethal - majority die,maternal effect" "cleavage furrow | embryonic stage | maternal effectFs(2)Ket-RX32),spindle | embryonic stage | maternal effectFs(2)Ket-RX32),cleavage furrow | embryonic stagenos.UTR.THsimVP16" FBgn0000550 Edg64CD Ecdysone-dependent gene 64CD http://flybase.net/reports/FBgn0000550.html gene Edg64 16-Dec-15 2015_12 prepupal stage epidermis

FBgn0052843 Dh31-R Diuretic hormone 31 Receptor http://flybase.net/reports/FBgn0052843.html "FBgn0033824, FBgn0033825, FBgn0046596, FBgn0046597" protein_coding_gene "0008036=diuretic hormone receptor activity, 0008188=neuropeptide receptor activity, 0004948=calcitonin receptor activity" 0007186=G-protein coupled receptor signaling pathway "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "CG17043, DH31-R1, CG17415, anon-WO0170980.137, anon-WO0170980.136, DH[[31]] receptor, DH31, DH31-R, dh31-R1, DH31-receptor, Calcitonin-like diuretic hormone receptor, Diuretic hormone 31 receptor 1, DmeCG32843, CG32843, DH31R, Dh31-R1, DH31 Receptor" "IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR003287=GPCR, family 2, calcitonin receptor family, IPR017981=GPCR, family 2-like, IPR017983=GPCR, family 2, secretin-like, conserved site, IPR000832=GPCR, family 2, secretin-like" CG32843 16-Dec-15 2015_12 "ENSDARG00000011473(calcrla),ENSDARG00000028845,ENSDARG00000011571(LOC567131),ENSDARG00000033955" ENSXETG00000013895(calcr) "ENSMUSG00000059588(Calcrl),ENSMUSG00000023964(Calcr)" "ENSG00000064989(CALCRL),ENSG00000004948(CALCR)" "viable,fertile" FBgn0266804 CR45266 http://flybase.net/reports/FBgn0266804.html non_protein_coding_gene CR45266 16-Dec-15 2015_12 FBgn0011984 tRNA:S7:23Ea transfer RNA:ser7:23Ea http://flybase.net/reports/FBgn0011984.html "FBgn0003831, FBgn0011968, FBgn0011979, FBgn0051951, FBgn0060065" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033405=UCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:ser, 777-3, CR31951, Ser-tRNA-7, AE002638.trna2-SerAGA, chr2L.trna35-SerAGA, tRNA:ser7:23Ea, tRNA[[Ser]], transfer RNA:ser, tRNA[Ser], transfer RNA:ser7, tRNA:ser7, tRNA-Ser7, tRNA:S:AGA:AE002638-a, tRNA:S, tRNA[[7]][Ser], tRNA ser7, tRNA:S7, tRNA[Ser][[7]]" CR31951 16-Dec-15 2015_12 FBgn0002193 l(3)63Bd lethal (3) 63Bd http://flybase.net/reports/FBgn0002193.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0044113 E(rst)C210 E(rst)C210 http://flybase.net/reports/FBgn0044113.html gene 0001745=compound eye morphogenesis C210 16-Dec-15 2015_12 FBgn0266647 CG45154 http://flybase.net/reports/FBgn0266647.html protein_coding_gene CR45154 CG45154 16-Dec-15 2015_12 FBgn0262869 Gfrl Glial cell line-derived neurotrophic family receptor-like http://flybase.net/reports/FBgn0262869.html "FBgn0261342, FBgn0261970, FBgn0083954, FBan0017205, FBgn0038794, FBgn0064953, FBgn0040573, FBgn0083955, FBpp0083305, FBtr0083897, FBpp0083304, FBtr0083896, FBgn0038793, FBgn0038792, FBgn0038791, FBgn0053518, FBgn0259820" protein_coding_gene "0050839=cell adhesion molecule binding, 0016167=glial cell-derived neurotrophic factor receptor activity" "0031362=anchored component of external side of plasma membrane, 0016020=membrane" "CG43224, CG34119, CG34118, CG4342, CG42401, munin, CG17203, mun, CG42801, CG42625, CG17208, GDNF Receptor-like, CG33518, BcDNA:GH26447, CG17205, CG17204, DmGfrl" IPR016017=GDNF/GAS1 CG43224 16-Dec-15 2015_12 FBgn0263563 mir-4956 mir-4956 stem loop http://flybase.net/reports/FBgn0263563.html miRNA_gene "dme-mir-4956, CR43548" CR43548 16-Dec-15 2015_12 FBgn0031858 CG17378 http://flybase.net/reports/FBgn0031858.html protein_coding_gene IPR022096=SBF1/SBF2 domain CG17378 16-Dec-15 2015_12 ENSDARG00000041599(zgc:91860) ENSXETG00000017409(KIAA0513) ENSMUSG00000031824(6430548M08Rik) ENSG00000135709(KIAA0513) "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0001792 l(1)Mb22 lethal (1) Mb22 http://flybase.net/reports/FBgn0001792.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031195 CG17600 http://flybase.net/reports/FBgn0031195.html FBgn0031193 protein_coding_gene 0016021=integral component of membrane CG17602 IPR007237=CD20-like family CG17600 16-Dec-15 2015_12 "viable,fertile" DRSC22753 I 1.741452663 -0.072786419 0.335203846 0.048923869 -0.906583808 0.016171867 FBgn0005733 l(1)TK218 lethal (1) TK218 http://flybase.net/reports/FBgn0005733.html gene l218 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0065625 l(2)SH0795 lethal (2) SH0795 http://flybase.net/reports/FBgn0065625.html gene l(2)SH2 0795 16-Dec-15 2015_12 "lethal,recessive" FBgn0005728 l(1)TK203 lethal (1) TK203 http://flybase.net/reports/FBgn0005728.html gene l203 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0039308 CG11889 http://flybase.net/reports/FBgn0039308.html "FBgn0053091, FBtr0084818, FBpp0084193, FBtr0084819, FBpp0084194, FBtr0084820, FBpp0084195" protein_coding_gene CG33091 "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG11889 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" DRSC14426 I 1.858612401 0.064515664 0.518968489 0.345428587 0.126351437 0.223857066 FBgn0002163 l(2)Sp7 lethal (2) Sp7 http://flybase.net/reports/FBgn0002163.html gene 16-Dec-15 2015_12 lethal FBgn0013558 l(3)2 lethal (3) 2 http://flybase.net/reports/FBgn0013558.html gene 16-Dec-15 2015_12 lethal FBgn0015924 crq croquemort http://flybase.net/reports/FBgn0015924.html "FBgn0011572, FBgn0044547, FBgn0051655" protein_coding_gene 0005044=scavenger receptor activity "0006909=phagocytosis, 0006911=phagocytosis, engulfment, 0048102=autophagic cell death, 0006955=immune response, 0042116=macrophage activation, 0006952=defense response, 0035071=salivary gland cell autophagic cell death, 0060099=regulation of phagocytosis, engulfment, 0002433=immune response-regulating cell surface receptor signaling pathway involved in phagocytosis, 0006915=apoptotic process, 0007155=cell adhesion, 0050764=regulation of phagocytosis, 0090382=phagosome maturation" "0005887=integral component of plasma membrane, 0016020=membrane" "CD36, Cqr, Croquemort, CD36-like, cqr, CG31655, CRQ, cqm, Cd36, CG4280, Crq, D-CD36, anon-WO0140519.8" IPR002159=CD36 antigen CG4280 16-Dec-15 2015_12 ENSXETG00000001195(SCARB1) " larval stage , embryonic stage | stage >=11 " " embryonic/larval hemocyte

, hemocyte

" "neuroanatomy defective,conditional,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional,phagolysosomeal),presumptive embryonic/larval central nervous system,embryonic/larval glial cell" FBgn0267188 CR45628 http://flybase.net/reports/FBgn0267188.html non_protein_coding_gene CR45628 16-Dec-15 2015_12 FBgn0028864 CG18477 http://flybase.net/reports/FBgn0028864.html FBgn0032568 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "BG:DS07108.1, SPH69" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG18477 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" FBgn0036010 Ir67a Ionotropic receptor 67a http://flybase.net/reports/FBgn0036010.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "DmelIR67a, IR67a, CG12525, ionotropic receptor 67a" CG12525 16-Dec-15 2015_12 viable FBgn0033352 PAN2 PAN2 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0033352.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 0004535=poly(A)-specific ribonuclease activity, 0003676=nucleic acid binding, 0005515=protein binding" "0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0006397=mRNA processing" 0031251=PAN complex "Pan2, PAN2, pan2, CG8232, A1Z7K9" "IPR028889=Ubiquitin specific protease domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR030843=PAB-dependent poly(A)-specific ribonuclease subunit PAN2, IPR028881=PAN2 domain, IPR013520=Exonuclease, RNase T/DNA polymerase III, IPR012337=Ribonuclease H-like domain, IPR017986=WD40-repeat-containing domain" CG8232 16-Dec-15 2015_12 YGL094C(PAN2) WBGene00017951(F31E3.4) ENSXETG00000009434(usp52) ENSMUSG00000005682(Pan2) ENSG00000135473(PAN2) "viable,fertile" FBgn0064140 sl(2)AM1 sl(2)AM1 http://flybase.net/reports/FBgn0064140.html gene unnamed 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0026206 mei-P26 meiotic P26 http://flybase.net/reports/FBgn0026206.html FBgn0027551 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" "0007281=germ cell development, 0007276=gamete generation, 0016567=protein ubiquitination, 0007126=meiotic nuclear division" 0005737=cytoplasm "mei-P26, CG12218, Mei-P26, BcDNA:GH10646, mei-p26, MEI-P26, AF145661" "IPR001258=NHL repeat, IPR003649=B-box, C-terminal, IPR013017=NHL repeat, subgroup, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000315=B-box-type zinc finger, IPR017907=Zinc finger, RING-type, conserved site, IPR011042=Six-bladed beta-propeller, TolB-like" CG12218 16-Dec-15 2015_12 "female sterile,recessive,neurophysiology defective,male fertile,meiotic cell cycle defective,semidominant,female fertile,reduced,wild-type,viable,sterile,male sterile,lethal" "egg chamber,nurse cell,egg,ovary,nucleolus & ovary,testis,ventral nerve cord,presumptive embryonic/larval peripheral nervous system,spermatozoon,spermatid,oocyte,male germline cyst,nucleolus,spermatocyte cyst" FBgn0035742 CG8629 http://flybase.net/reports/FBgn0035742.html FBgn0047118 protein_coding_gene "0004857=enzyme inhibitor activity, 0000062=fatty-acyl-CoA binding, 0050809=diazepam binding" 0042049=cellular acyl-CoA homeostasis BcDNA:RE33457 "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000582=Acyl-CoA-binding protein, ACBP" CG8629 16-Dec-15 2015_12 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0266673 Sec10 Sec10 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266673.html "FBgn0042694, FBgn0266613, FBgn0266665, FBgn0027103" protein_coding_gene 0008013=beta-catenin binding "0016080=synaptic vesicle targeting, 0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0048278=vesicle docking, 0006887=exocytosis, 0090522=vesicle tethering involved in exocytosis, 0016081=synaptic vesicle docking" 0000145=exocyst "CG6159, dSec10, sec10, Sec10p, P71, dsec10" IPR009976=Exocyst complex component Sec10-like CG6159 16-Dec-15 2015_12 ENSDARG00000060323(zgc:175220) YLR166C(SEC10) WBGene00016376(sec-10) ENSXETG00000011995(EXOC5) ENSMUSG00000061244(Exoc5) ENSG00000070367(EXOC5) FBgn0002100 l(2)57Da lethal (2) 57Da http://flybase.net/reports/FBgn0002100.html gene l(2)57CDb 16-Dec-15 2015_12 lethal FBgn0000911 fs(1)M121 female sterile (1) M121 http://flybase.net/reports/FBgn0000911.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0050075 CG30075 http://flybase.net/reports/FBgn0050075.html protein_coding_gene "IPR011990=Tetratricopeptide-like helical domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG30075 16-Dec-15 2015_12 viable FBgn0037364 Rab23 Rab23 http://flybase.net/reports/FBgn0037364.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0015031=protein transport, 0001738=morphogenesis of a polarized epithelium, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0007224=smoothened signaling pathway" "0045202=synapse, 0043025=neuronal cell body, 0005886=plasma membrane, 0055037=recycling endosome, 0005737=cytoplasm, 0031982=vesicle" "rab23, CG2108, DmRab23, Q9VNG6" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type" CG2108 16-Dec-15 2015_12 ENSDARG00000004151(rab23) ENSXETG00000004449(rab23) ENSMUSG00000004768(Rab23) ENSG00000112210(RAB23) "viable,visible,partially lethal - majority die,recessive,planar polarity defective" "wing hair,cell autonomous,somatic clone,wing,microchaeta,leg,tergite,sternite" FBgn0030686 mRpL3 mitochondrial ribosomal protein L3 http://flybase.net/reports/FBgn0030686.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005762=mitochondrial large ribosomal subunit, 0005763=mitochondrial small ribosomal subunit" "CG8288, L3" "IPR019927=Ribosomal protein L3, bacterial/organelle-type, IPR000597=Ribosomal protein L3, IPR009000=Translation protein, beta-barrel domain" CG8288 16-Dec-15 2015_12 ENSDARG00000003511(mrpl3) YGR220C(MRPL9) WBGene00016142(C26E6.6) ENSXETG00000001845(Mrpl3) ENSMUSG00000032563(Mrpl3) ENSG00000114686(MRPL3) "viable,fertile,visible" trichogen cell FBgn0261976 Psf2 Psf2 http://flybase.net/reports/FBgn0261976.html "FBgn0031599, FBgn0065620" protein_coding_gene 0043138=3'-5' DNA helicase activity "0046331=lateral inhibition, 0030261=chromosome condensation, 0006271=DNA strand elongation involved in DNA replication, 0022008=neurogenesis, 1900087=positive regulation of G1/S transition of mitotic cell cycle, 0032784=regulation of DNA-templated transcription, elongation" "0000811=GINS complex, 0005634=nucleus" "l(2)SH2 0805, CG18013, l(2)SH0805, P{lacW}l(2)SH0805[SH0805], lethal (2) SH0805" "IPR021151=GINS complex, IPR007257=DNA replication complex GINS protein Psf2" CG18013 16-Dec-15 2015_12 ENSDARG00000002304(gins2) YJL072C(PSF2) WBGene00009287(F31C3.5) ENSXETG00000004469(psf2) ENSMUSG00000031821(Gins2) ENSG00000131153(GINS2) DRSC00516 IE 2.123951156 0.970750155 2.543377399 1.346589113 -0.566711336 -1.002815819 FBgn0060381 l(3)S134612b lethal (3) S134612b http://flybase.net/reports/FBgn0060381.html gene 1346/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0030407 CG2543 http://flybase.net/reports/FBgn0030407.html protein_coding_gene "0005524=ATP binding, 0004326=tetrahydrofolylpolyglutamate synthase activity" 0046901=tetrahydrofolylpolyglutamate biosynthetic process "0005737=cytoplasm, 0005739=mitochondrion" "IPR001645=Folylpolyglutamate synthetase, IPR004101=Mur ligase, C-terminal, IPR018109=Folylpolyglutamate synthetase, conserved site, IPR013221=Mur ligase, central, IPR023600=Folylpolyglutamate synthase, eukaryota" CG2543 16-Dec-15 2015_12 ENSDARG00000044809(fpgs) YOR241W(MET7) WBGene00017777(F25B5.6) ENSXETG00000022007() ENSMUSG00000009566(Fpgs) ENSG00000136877(FPGS) "lethal,recessive,viable" FBgn0264659 scrub scrub http://flybase.net/reports/FBgn0264659.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0013224 E(hopTum) Enhancer of hopTum http://flybase.net/reports/FBgn0013224.html gene 16-Dec-15 2015_12 FBgn0051066 CG31066 http://flybase.net/reports/FBgn0051066.html protein_coding_gene 16-Dec-15 2015_12 FBgn0261360 CG42637 http://flybase.net/reports/FBgn0261360.html FBgn0260654 protein_coding_gene "0004872=receptor activity, 0005524=ATP binding, 0004383=guanylate cyclase activity, 0004672=protein kinase activity" "0019934=cGMP-mediated signaling, 0009190=cyclic nucleotide biosynthetic process, 0006468=protein phosphorylation" 0005887=integral component of plasma membrane "IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828=Receptor, ligand binding region, IPR028082=Periplasmic binding protein-like I, IPR011009=Protein kinase-like domain" CG42637 16-Dec-15 2015_12 FBgn0038730 CG6300 http://flybase.net/reports/FBgn0038730.html protein_coding_gene "0005324=long-chain fatty acid transporter activity, 0003824=catalytic activity" 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR020845=AMP-binding, conserved site, IPR000873=AMP-dependent synthetase/ligase" CG6300 16-Dec-15 2015_12 DRSC16014 IK -0.226074953 2.040708663 0.507068893 -0.321835425 1.830274522 1.075702349 FBgn0014411 Vps26 Vacuolar protein sorting 26 http://flybase.net/reports/FBgn0014411.html protein_coding_gene 0008565=protein transporter activity "0006605=protein targeting, 0006886=intracellular protein transport, 0007040=lysosome organization, 0042147=retrograde transport, endosome to Golgi" "0030906=retromer complex, inner shell, 0005768=endosome" "dVps26, DmVps26, vps26, dvps26, anon-sts13, ESTS:131F2S, Dvps26, EG:63B12.8, 131F2S, CG14804" IPR028934=Vacuolar protein sorting protein 26 related CG14804 16-Dec-15 2015_12 "ENSDARG00000015823(si:ch211-277g22.3),ENSDARG00000055433(vps26bl)" YJL053W(PEP8) WBGene00006931(vps-26) ENSXETG00000008335(TTpA009m02.1) ENSMUSG00000031988(Vps26b) "ENSG00000151502(VPS26B),ENSG00000122958(VPS26A)" "neurophysiology defective,progressive,visible,partially lethal - majority die,some die during pupal stage" "photoreceptor cell,progressive,rhabdomere,endosome,lysosome,trichogen cell,mesothoracic tergum" FBgn0036040 CG6749 http://flybase.net/reports/FBgn0036040.html protein_coding_gene "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG6749 16-Dec-15 2015_12 "ENSDARG00000062398,ENSDARG00000006636(sc:d0319),ENSDARG00000041912" ENSXETG00000015538(IGFALS) ENSG00000099769(IGFALS) viable FBgn0085384 CG34355 http://flybase.net/reports/FBgn0085384.html "FBgn0039123, FBgn0040596" protein_coding_gene "lincRNA.840, CG12492, CG13818" "IPR019545=DM13 domain, IPR005018=DOMON domain" CG34355 16-Dec-15 2015_12 WBGene00020921(W01C8.5) FBgn0027562 CG10345 http://flybase.net/reports/FBgn0027562.html protein_coding_gene 0005044=scavenger receptor activity "0006952=defense response, 0007155=cell adhesion" "0005887=integral component of plasma membrane, 0016020=membrane" "BcDNA:GH08773, BcDNA" "IPR002159=CD36 antigen, IPR005428=Adhesion molecule CD36" CG10345 16-Dec-15 2015_12 "viable,fertile" FBgn0033809 CG4630 http://flybase.net/reports/FBgn0033809.html protein_coding_gene 0015226=carnitine transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG4630 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" "partially lethal - majority die,some die during pupal stage" FBgn0002515 l(3)Sp9 lethal (3) Sp9 http://flybase.net/reports/FBgn0002515.html gene 16-Dec-15 2015_12 lethal FBgn0004532 l(4)102ABh lethal (4) 102ABh http://flybase.net/reports/FBgn0004532.html gene "lethal(4) Solway, Tennessee-3, l(4)ST-3, l(4)25, l(4)ABh" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266302 CR44967 http://flybase.net/reports/FBgn0266302.html non_protein_coding_gene CR44967 16-Dec-15 2015_12 FBgn0043877 mecE mechanosensory E http://flybase.net/reports/FBgn0043877.html gene 0050954=sensory perception of mechanical stimulus 16-Dec-15 2015_12 FBgn0039436 TwdlB TweedleB http://flybase.net/reports/FBgn0039436.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix "CG6478, Tweedle B" IPR004145=Domain of unknown function DUF243 CG6478 16-Dec-15 2015_12 FBgn0028264 l(2)46Ck lethal (2) 46Ck http://flybase.net/reports/FBgn0028264.html gene "Q, Complementation group Q" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0261284 bou boudin http://flybase.net/reports/FBgn0261284.html "FBgn0001425, FBgn0029927, FBgn0047134" protein_coding_gene "0035152=regulation of tube architecture, open tracheal system, 0019991=septate junction assembly" "0005576=extracellular region, 0046658=anchored component of plasma membrane" "l(1)jnL4, BcDNA:RE28342, l(1)6Ea, lethal (1) 6Ea, Boudin, JNXL4, CG14430, jnL4" CG14430 16-Dec-15 2015_12 FBgn0082633 S(CycEJP)2.4 S(CycEJP)2.4 http://flybase.net/reports/FBgn0082633.html gene Complementation group 2.4 16-Dec-15 2015_12 "lethal,recessive" FBgn0044813 T:ZnF-su(Hw) Zinc-finger DNA-binding domain of su(Hw) http://flybase.net/reports/FBgn0044813.html engineered_tag "T:su(Hw), suppressor of Hairy wing DNA binding domain" 16-Dec-15 2015_12 FBgn0035410 CG14964 http://flybase.net/reports/FBgn0035410.html protein_coding_gene 0017022=myosin binding CT34810 "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set" CG14964 16-Dec-15 2015_12 viable FBgn0038465 Irc Immune-regulated catalase http://flybase.net/reports/FBgn0038465.html protein_coding_gene "0020037=heme binding, 0004096=catalase activity, 0004601=peroxidase activity" "0055114=oxidation-reduction process, 0006979=response to oxidative stress" "peroxidase, Peroxidase, immune-regulated catalase, immune-related catalase, CG8913, IRC" "IPR010255=Haem peroxidase, IPR019791=Haem peroxidase, animal" CG8913 16-Dec-15 2015_12 "chemical sensitive,immune response defective,short lived,conditional" FBgn0001062 Fs(3)Pil Female sterile (3) Pilis http://flybase.net/reports/FBgn0001062.html gene "Fs(3)Pilis, Fs(3)Sz20" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0020574 anon-59Ck anon-59Ck http://flybase.net/reports/FBgn0020574.html gene 16-Dec-15 2015_12 FBgn0024602 oop out of place http://flybase.net/reports/FBgn0024602.html gene 0001746=Bolwig's organ morphogenesis 16-Dec-15 2015_12 viable "Bolwig organ,Bolwig nerve" FBgn0005304 ms(1)6S male sterile (1) 6S http://flybase.net/reports/FBgn0005304.html gene 16-Dec-15 2015_12 male sterile "spermatozoon,spermatid axoneme,Nebenkern derivative,acrosomal granule,spermatid & nucleus" FBgn0262251 mir-977 mir-977 stem loop http://flybase.net/reports/FBgn0262251.html miRNA_gene "977, CR42958, dme-mir-977, miR-977" CR42958 16-Dec-15 2015_12 "lethal,visible" "eye,wing" FBgn0266978 CR45429 http://flybase.net/reports/FBgn0266978.html non_protein_coding_gene CR45429 16-Dec-15 2015_12 FBgn0032699 CG10383 http://flybase.net/reports/FBgn0032699.html protein_coding_gene "0016788=hydrolase activity, acting on ester bonds" "0006886=intracellular protein transport, 0006505=GPI anchor metabolic process, 0008340=determination of adult lifespan" "IPR029058=Alpha/Beta hydrolase fold, IPR011989=Armadillo-like helical, IPR012908=GPI inositol-deacylase PGAP1-like, IPR016024=Armadillo-type fold" CG10383 16-Dec-15 2015_12 ENSDARG00000056121(serac1) WBGene00008925(F17H10.1) ENSXETG00000023344(SERAC1) ENSG00000122335(SERAC1) "long lived,viable" FBgn0001901 l(2)22Ab lethal (2) 22Ab http://flybase.net/reports/FBgn0001901.html gene "l(2)neh-15, l(2)neh15" 16-Dec-15 2015_12 lethal FBgn0086367 t tan http://flybase.net/reports/FBgn0086367.html "FBgn0003662, FBgn0030106" protein_coding_gene "0003832=beta-alanyl-dopamine hydrolase activity, 0031964=beta-alanyl-histamine hydrolase activity, 0016787=hydrolase activity" "0001692=histamine metabolic process, 0048067=cuticle pigmentation, 0001694=histamine biosynthetic process, 0007601=visual perception, 0042416=dopamine biosynthetic process, 0007629=flight behavior" 0005829=cytosol "on-transient defective, Tan, CG12120, tan" IPR005079=Peptidase C45 CG12120 16-Dec-15 2015_12 FBgn0067881 Mod(Prat:bw)2-1 Mod(Prat:bw)2-1 http://flybase.net/reports/FBgn0067881.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0267620 CR45958 http://flybase.net/reports/FBgn0267620.html non_protein_coding_gene CR45958 16-Dec-15 2015_12 FBgn0020288 l(2)k06407 lethal (2) k06407 http://flybase.net/reports/FBgn0020288.html gene lp 16-Dec-15 2015_12 "lethal,recessive" FBgn0039979 CR40282 http://flybase.net/reports/FBgn0039979.html "FBan0017706, FBgn0058282" pseudogene_attribute "CG40282, CG17706" CR40282 16-Dec-15 2015_12 DRSC07814 I 1.836631432 -0.577866393 1.075018821 1.125845627 -0.665061477 -0.836474188 FBgn0035886 Jon66Ci Jonah 66Ci http://flybase.net/reports/FBgn0035886.html FBgn0001287 protein_coding_gene "0004175=endopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "SP171, Jon66C, Jonah 66C, CG7118, 66C" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG7118 16-Dec-15 2015_12 "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0037618 CG11762 http://flybase.net/reports/FBgn0037618.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus i36 "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG11762 16-Dec-15 2015_12 WBGene00010770(K11D2.4) DRSC14376 K 0.378752336 -0.699848862 -0.970844117 -0.166193664 1.759686141 -0.060889491 FBgn0036451 CG9425 http://flybase.net/reports/FBgn0036451.html protein_coding_gene 0046872=metal ion binding "IPR011990=Tetratricopeptide-like helical domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR003593=AAA+ ATPase domain, IPR000571=Zinc finger, CCCH-type" CG9425 16-Dec-15 2015_12 ENSDARG00000030560(zgc:77407) ENSXETG00000015395(HELZ) ENSMUSG00000020721(Helz) ENSG00000198265(HELZ) heart primordium FBgn0030466 CG15744 http://flybase.net/reports/FBgn0030466.html protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "CT35992, unnamed, Q7KV24_DROME" "IPR001611=Leucine-rich repeat, IPR003599=Immunoglobulin subtype, IPR007110=Immunoglobulin-like domain, IPR003591=Leucine-rich repeat, typical subtype, IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR017981=GPCR, family 2-like, IPR000483=Cysteine-rich flanking region, C-terminal, IPR000832=GPCR, family 2, secretin-like" CG15744 16-Dec-15 2015_12 "ENSXETG00000024325(GPR124),ENSXETG00000020470(GPR125)" "ENSMUSG00000029090(Gpr125),ENSMUSG00000031486(Gpr124)" "ENSG00000152990(GPR125),ENSG00000020181(GPR124)" viable FBgn0011777 l(2)DTS18WF lethal (2) DTS18 Wright & Falke http://flybase.net/reports/FBgn0011777.html FBgn0005147 gene "DTS18, l(2)DTS18" 16-Dec-15 2015_12 "lethal,dominant,heat sensitive,female sterile" FBgn0040332 EY2-5 EY2-5 http://flybase.net/reports/FBgn0040332.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082993 snoRNA:ë¬28S-1936 snoRNA:ë¬28S-1936 http://flybase.net/reports/FBgn0082993.html snoRNA_gene "psi28s-1936, CR34530" CR34530 16-Dec-15 2015_12 FBgn0083062 sgo smeagol http://flybase.net/reports/FBgn0083062.html gene "0007111=meiosis II cytokinesis, 0007110=meiosis I cytokinesis, 0051225=spindle assembly, 0000915=actomyosin contractile ring assembly" 16-Dec-15 2015_12 "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic cell cycle | male,contractile ring & meiotic cell cycle | male,spermatid & nucleus | supernumerarymbc-R1),spindle & meiotic cell cycle | malembc-R1),contractile ring & meiotic cell cycle | malembc-R1)" FBgn0039768 CG15533 http://flybase.net/reports/FBgn0039768.html protein_coding_gene 0004767=sphingomyelin phosphodiesterase activity "0006685=sphingomyelin catabolic process, 0006684=sphingomyelin metabolic process" "aSMase, Acid Sphingomyelinase" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR008139=Saposin B type domain, IPR029052=Metallo-dependent phosphatase-like, IPR011160=Sphingomyelin phosphodiesterase" CG15533 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0082950 snoRNA:Me18S-G1952 snoRNA:Me18S-G1952 http://flybase.net/reports/FBgn0082950.html snoRNA_gene "CR34536, Me18S-G1952" CR34536 16-Dec-15 2015_12 FBgn0060787 l(3)S059508 lethal (3) S059508 http://flybase.net/reports/FBgn0060787.html gene 0595/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0033002 CG17589 http://flybase.net/reports/FBgn0033002.html protein_coding_gene 16-Dec-15 2015_12 FBgn0265891 CR44680 http://flybase.net/reports/FBgn0265891.html non_protein_coding_gene CR44680 16-Dec-15 2015_12 FBgn0033349 CG8243 http://flybase.net/reports/FBgn0033349.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity gap40 IPR001164=Arf GTPase activating protein CG8243 16-Dec-15 2015_12 "ENSDARG00000031302(smap1),ENSDARG00000061446(si:dkeyp-89d7.2)" YIL044C(AGE2) WBGene00012359(W09D10.1) "ENSXETG00000017900(SMAP1),ENSXETG00000004776(SMAP2)" "ENSMUSG00000032870(Smap2),ENSMUSG00000026155(Smap1)" "ENSG00000112305(SMAP1),ENSG00000084070(SMAP2)" lethal FBgn0267901 CR46189 http://flybase.net/reports/FBgn0267901.html pseudogene_attribute CG12717-related CR46189 16-Dec-15 2015_12 FBgn0001217 Hsc70-2 Heat shock protein cognate 2 http://flybase.net/reports/FBgn0001217.html protein_coding_gene 0051082=unfolded protein binding "0009408=response to heat, 0006457=protein folding" 0005739=mitochondrion "heat shock protein cognate-2, HSP7B_DROME, HSC70-2, dhsc70, Hsp cognate 2, HSC2, CG7756, Hsc70, Hsc2, HSC70, hsc2, Hsc70.2, Hs protein cognate 2, Hsc-2, hsc70, HSC-70" "IPR013126=Heat shock protein 70 family, IPR018181=Heat shock protein 70, conserved site, IPR029048=Heat shock protein 70kD, C-terminal domain, IPR029047=Heat shock protein 70kD, peptide-binding domain" CG7756 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0017438 anon-28Ca anon-28Ca http://flybase.net/reports/FBgn0017438.html gene unnamed 16-Dec-15 2015_12 FBgn0029700 CG15576 http://flybase.net/reports/FBgn0029700.html protein_coding_gene CG15576 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0044388 Scim6 Sensitized chromosome inheritance modifier 6 http://flybase.net/reports/FBgn0044388.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0262593 Shab Shaker cognate b http://flybase.net/reports/FBgn0262593.html "FBgn0003383, FBgn0035381" protein_coding_gene "0005251=delayed rectifier potassium channel activity, 0005249=voltage-gated potassium channel activity" "0048812=neuron projection morphogenesis, 0060025=regulation of synaptic activity, 0008016=regulation of heart contraction, 0051260=protein homooligomerization, 0001508=action potential, 0008345=larval locomotory behavior, 0007268=synaptic transmission, 0006813=potassium ion transport, 0055085=transmembrane transport" "0008076=voltage-gated potassium channel complex, 0005886=plasma membrane, 0016021=integral component of membrane" "dShab, Shaker, CG43128, shab, shb, CG9965, Kv2, CG1066" "IPR003131=Potassium channel tetramerisation-type BTB domain, IPR005821=Ion transport domain, IPR003971=Potassium channel, voltage dependent, Kv9, IPR000210=BTB/POZ domain, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR028325=Voltage-gated potassium channel, IPR011333=POZ domain, IPR003091=Potassium channel, IPR003968=Potassium channel, voltage dependent, Kv" CG43128 16-Dec-15 2015_12 "ENSDARG00000060095(LOC555284),ENSDARG00000038862(kcnb2)" ENSXETG00000016003(KCNB1) " embryonic stage | late , pupal stage " FBgn0058358 CG40358 http://flybase.net/reports/FBgn0058358.html protein_coding_gene 16-Dec-15 2015_12 FBgn0053427 5SrRNA:CR33427 5SrRNA:CR33427 http://flybase.net/reports/FBgn0053427.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33427 CR33427 16-Dec-15 2015_12 FBgn0266416 CR45056 http://flybase.net/reports/FBgn0266416.html non_protein_coding_gene CR45056 16-Dec-15 2015_12 FBgn0042693 PP2A-B' PP2A-B' http://flybase.net/reports/FBgn0042693.html "FBgn0038572, FBgn0038573, FBgn0047274, FBgn0062021" protein_coding_gene 0008601=protein phosphatase type 2A regulator activity "0043066=negative regulation of apoptotic process, 0006470=protein dephosphorylation, 0006914=autophagy, 0070328=triglyceride homeostasis, 0007528=neuromuscular junction development, 0007165=signal transduction, 0045498=sex comb development, 0097479=synaptic vesicle localization, 0007274=neuromuscular synaptic transmission" 0000159=protein phosphatase type 2A complex "dPP2A, PP2A B' regulatory subunit, Well Rounded, PP2A B', PP2A-B, i234, regulatory B' subunit of PP2A, dPP2A,B', PP2A[B'-1], PP2A, PP2A B' subunit, B'/PR61, well-rounded, protein phosphatase 2A, protein phosphatase 2A B', pp2A-B', B56-1, dB56-1, B', dPP2A-B56-1, Protein phosphatase 2A regulatory B subunit, CG 7913, Wrd, CG7913, well rounded, CG7901, protein phosphatase 2A-B', BcDNA:GM05554, wrd, anon-WO0118547.420" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR002554=Protein phosphatase 2A, regulatory B subunit, B56" CG7913 16-Dec-15 2015_12 "ENSDARG00000014428(zgc:77529),ENSDARG00000031200(ppp2r5c)" YOR014W(RTS1) WBGene00007554(pptr-2) ENSXETG00000010224(PPP2R5C) "ENSMUSG00000059409(Ppp2r5d),ENSMUSG00000017843(Ppp2r5c)" "ENSG00000112640(PPP2R5D),ENSG00000078304(PPP2R5C)" "viable,female fertile,male fertile,fertile,short lived,partially lethal - majority die,lethal,visible,neuroanatomy defective,recessive,neurophysiology defective" "salivary gland,NMJ bouton | larval stage,neuromuscular junction | larval stage,bouton & neuromuscular junction | larval stage,microtubule & neuromuscular junction | larval stage,bouton & neuromuscular junction | larval stageDG4),neuromuscular junction,bouton" FBgn0037469 Dpck Dephospho-CoA kinase http://flybase.net/reports/FBgn0037469.html protein_coding_gene "0004140=dephospho-CoA kinase activity, 0005524=ATP binding" 0015937=coenzyme A biosynthetic process 0012505=endomembrane system "CG1939, DPCK, dephospho-CoA kinase, dDPCK" "IPR001977=Dephospho-CoA kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG1939 16-Dec-15 2015_12 ENSDARG00000061638(dcakd) YDR196C(CAB5) WBGene00011500(T05G5.5) ENSXETG00000003179(DCAKD) ENSMUSG00000020935(Dcakd) ENSG00000172992(DCAKD) "viable,visible,fertile" "trichogen cell,mesothoracic tergum" FBgn0261722 fwe flower http://flybase.net/reports/FBgn0261722.html "FBgn0259121, FBgn0036533, FBgn0062151" protein_coding_gene 0005262=calcium channel activity "0048488=synaptic vesicle endocytosis, 0043525=positive regulation of neuron apoptotic process, 0046530=photoreceptor cell differentiation, 0042981=regulation of apoptotic process" "0044214=spanning component of plasma membrane, 0030285=integral component of synaptic vesicle membrane" "Flower, flower, dFwe, CG6151, anon-WO0118547.242" "IPR024947=Calcium channel flower, IPR019365=TVP18/Calcium channel flower" CG6151 16-Dec-15 2015_12 ENSDARG00000068209 WBGene00008973(F20D1.1) ENSXETG00000006883(C9orf7) ENSMUSG00000015488(5930434B04Rik) ENSG00000160325(C9orf7) FBgn0265653 CR44460 http://flybase.net/reports/FBgn0265653.html non_protein_coding_gene lincRNA.351 CR44460 16-Dec-15 2015_12 FBgn0032645 CG15142 http://flybase.net/reports/FBgn0032645.html protein_coding_gene IPR019187=Cyclin-dependent kinase 2-associated protein CG15142 16-Dec-15 2015_12 ENSDARG00000069700(cdk2ap2) partially lethal - majority die FBgn0003004 oph ophthalmopedia http://flybase.net/reports/FBgn0003004.html gene 16-Dec-15 2015_12 visible "eye disc,eye" FBgn0013699 mt:tRNA:L:UUR mitochondrial leucine UUR tRNA http://flybase.net/reports/FBgn0013699.html FBgn0002867 tRNA_gene 0030533=triplet codon-amino acid adaptor activity 0006412=translation 0005739=mitochondrion "mtdbD00006298, CR34068" CR34068 16-Dec-15 2015_12 FBgn0265948 CR44735 http://flybase.net/reports/FBgn0265948.html non_protein_coding_gene lincRNA.162 CR44735 16-Dec-15 2015_12 FBgn0046708 GIIID GIIID http://flybase.net/reports/FBgn0046708.html gene 0004623=phospholipase A2 activity 0005576=extracellular region dGIIID 16-Dec-15 2015_12 FBgn0036240 CG6928 http://flybase.net/reports/FBgn0036240.html protein_coding_gene "0005215=transporter activity, 0015381=high-affinity sulfate transmembrane transporter activity" "0055085=transmembrane transport, 0008272=sulfate transport" 0016021=integral component of membrane "IPR001902=SLC26A/SulP transporter, IPR002645=STAS domain, IPR011547=SLC26A/SulP transporter domain" CG6928 16-Dec-15 2015_12 "YLR092W(SUL2),YBR294W(SUL1)" ENSXETG00000019624(SLC26A11) "viable,fertile" FBgn0014991 l(2)46Dg lethal (2) 46Dg http://flybase.net/reports/FBgn0014991.html gene "XIII, Group XIII" 16-Dec-15 2015_12 lethal FBgn0083154 S(smoDN)166 Suppressor of smoDN 166 http://flybase.net/reports/FBgn0083154.html gene 16-Dec-15 2015_12 FBgn0044473 EP1534 EP1534 http://flybase.net/reports/FBgn0044473.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective FBgn0052374 CG32374 http://flybase.net/reports/FBgn0052374.html FBgn0035796 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG8528, SP148" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG32374 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0053396 5SrRNA:CR33396 5SrRNA:CR33396 http://flybase.net/reports/FBgn0053396.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33396 CR33396 16-Dec-15 2015_12 FBgn0044817 Ste12DOR Stellate 12D orphon http://flybase.net/reports/FBgn0044817.html FBgn0052616 protein_coding_gene 0019887=protein kinase regulator activity 0005956=protein kinase CK2 complex "Stellate orphon, SteDOR, SC-1, Ste, CG32616" "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical, IPR016150=Casein kinase II, regulatory subunit, beta-sheet" CG32616 16-Dec-15 2015_12 FBgn0051518 tRNA:CR31518 transfer RNA:CR31518 http://flybase.net/reports/FBgn0051518.html "FBgn0011875, FBgn0060209" tRNA_gene "0033463=GGA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:gly:90DE, AE002708.trna19-GlyTCC, chr3R.trna25-GlyTCC, tRNA:G:90DE, CR31518, tRNA:G:TCC:AE002708-b, tRNA[Gly][[GGA]], tRNA:gly:90DE" CR31518 16-Dec-15 2015_12 FBgn0033499 CG12914 http://flybase.net/reports/FBgn0033499.html protein_coding_gene CG12914 16-Dec-15 2015_12 viable FBgn0032286 CG7300 http://flybase.net/reports/FBgn0032286.html protein_coding_gene CG7300 16-Dec-15 2015_12 FBgn0034032 CG8195 http://flybase.net/reports/FBgn0034032.html protein_coding_gene 0016021=integral component of membrane IPR000620=EamA domain CG8195 16-Dec-15 2015_12 "ENSDARG00000014487(LOC100001581),ENSDARG00000059850(LOC100332537)" "YML018C(),YDR438W(THI74)" WBGene00015009(B0041.5) "ENSXETG00000011984(SLC35F4),ENSXETG00000014564(SLC35F3)" ENSMUSG00000026342(Slc35f5) ENSG00000115084(SLC35F5) viable FBgn0266591 CG45116 http://flybase.net/reports/FBgn0266591.html protein_coding_gene CG45116 16-Dec-15 2015_12 FBgn0051092 LpR2 Lipophorin receptor 2 http://flybase.net/reports/FBgn0051092.html "FBgn0039361, FBgn0039362" protein_coding_gene "0071813=lipoprotein particle binding, 0005509=calcium ion binding, 0005041=low-density lipoprotein receptor activity" "0032370=positive regulation of lipid transport, 0048812=neuron projection morphogenesis" 0005886=plasma membrane "a2M-receptor-like, lipophorin receptor 2, LDLR, low-density lipoprotein receptor, LDL-receptor-related protein, lpr2, LDLR-like, LpR2, CG31092, Lpr2, CG4823, CG4834" "IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR011042=Six-bladed beta-propeller, TolB-like, IPR013032=EGF-like, conserved site, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR001881=EGF-like calcium-binding domain, IPR000033=LDLR class B repeat, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG31092 16-Dec-15 2015_12 ENSDARG00000006257(vldlr) WBGene00020481(T13C2.6) "ENSXETG00000011709(VLDLR),ENSXETG00000008073(LRP8),ENSXETG00000009352(LDLR)" "ENSMUSG00000024924(Vldlr),ENSMUSG00000028613,ENSMUSG00000032193(Ldlr)" "ENSG00000147852(VLDLR),ENSG00000130164(LDLR),ENSG00000157193(LRP8)" "viable,female sterile,fertile" lipid particle FBgn0266831 CR45293 http://flybase.net/reports/FBgn0266831.html non_protein_coding_gene CR45293 16-Dec-15 2015_12 FBgn0260321 GSd206 http://flybase.net/reports/FBgn0260321.html gene 16-Dec-15 2015_12 lethal FBgn0266979 CR45430 http://flybase.net/reports/FBgn0266979.html non_protein_coding_gene CR45430 16-Dec-15 2015_12 FBgn0085534 CG40910 http://flybase.net/reports/FBgn0085534.html FBan0040910 protein_coding_gene 16-Dec-15 2015_12 FBgn0026742 anon-45Ab anon-45Ab http://flybase.net/reports/FBgn0026742.html gene CLOT5200 16-Dec-15 2015_12 FBgn0086231 S149 http://flybase.net/reports/FBgn0086231.html gene 0003714=transcription corepressor activity 16-Dec-15 2015_12 FBgn0030148 CG3106 http://flybase.net/reports/FBgn0030148.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG3106 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" viable FBgn0060886 l(3)S044729 lethal (3) S044729 http://flybase.net/reports/FBgn0060886.html gene 0447/29 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0060424 l(3)S127508 lethal (3) S127508 http://flybase.net/reports/FBgn0060424.html gene 1275/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0262980 CG43288 http://flybase.net/reports/FBgn0262980.html protein_coding_gene lincRNA.945 CG43288 16-Dec-15 2015_12 FBgn0261610 CG42699 http://flybase.net/reports/FBgn0261610.html "FBgn0029803, FBgn0029808" protein_coding_gene "CG15770, CG4064" CG42699 16-Dec-15 2015_12 FBgn0060647 l(3)S083805 lethal (3) S083805 http://flybase.net/reports/FBgn0060647.html gene 0838/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0065101 snmRNA:204 small non-messenger RNA 204 http://flybase.net/reports/FBgn0065101.html FBgn0053657 non_protein_coding_gene "CR33657, Dm-204" CR33657 16-Dec-15 2015_12 FBgn0020866 bsd bashed http://flybase.net/reports/FBgn0020866.html gene 16-Dec-15 2015_12 FBgn0001893 l(2)21Dg lethal (2) 21Dg http://flybase.net/reports/FBgn0001893.html gene "l(2)neh-7, l(2)neh7" 16-Dec-15 2015_12 lethal FBgn0259875 Su(Ste):CR42444 Su(Ste):CR42444 http://flybase.net/reports/FBgn0259875.html non_protein_coding_gene "RR41456, CR42444" CR42444 16-Dec-15 2015_12 FBgn0021797 l(2)k17003 lethal (2) k17003 http://flybase.net/reports/FBgn0021797.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0031106 Syx16 Syntaxin 16 http://flybase.net/reports/FBgn0031106.html protein_coding_gene "0005484=SNAP receptor activity, 0005515=protein binding" "0007269=neurotransmitter secretion, 0048193=Golgi vesicle transport, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0016081=synaptic vesicle docking" "0016021=integral component of membrane, 0031201=SNARE complex, 0005764=lysosome, 0005794=Golgi apparatus, 0005886=plasma membrane, 0000139=Golgi membrane" "syntaxin 16, Syntaxin16, CG1467, Dm Syx16, dSyx 16, SYX16, Syx, dSyntaxin16, Syntaxin, DmSyx16, dSyx16, syntaxin" "IPR000727=Target SNARE coiled-coil homology domain, IPR010989=t-SNARE, IPR006012=Syntaxin/epimorphin, conserved site" CG1467 16-Dec-15 2015_12 ENSDARG00000003307(stx16) "YOL018C(TLG2),YOR036W(PEP12)" WBGene00022534(syn-16) ENSXETG00000004193(STX16) ENSMUSG00000027522(Stx16) ENSG00000124222(STX16) viable FBgn0065263 l(2)SH2079 lethal (2) SH2079 http://flybase.net/reports/FBgn0065263.html gene l(2)SH2 2079 16-Dec-15 2015_12 "lethal,recessive" FBgn0019853 anon-VIII anon-VIII http://flybase.net/reports/FBgn0019853.html gene VIII 16-Dec-15 2015_12 FBgn0027344 fs(2)E9b fs(2)E9b http://flybase.net/reports/FBgn0027344.html FBgn0000962 gene "fs2.9, fs(2)E9, female sterile(2)E9" 16-Dec-15 2015_12 female fertile FBgn0040704 CG11930 http://flybase.net/reports/FBgn0040704.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060878 l(3)S045507a lethal (3) S045507a http://flybase.net/reports/FBgn0060878.html gene 0455/07 16-Dec-15 2015_12 lethal FBgn0041135 l(2)44Fg lethal (2) 44Fg http://flybase.net/reports/FBgn0041135.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0003281 rs rose http://flybase.net/reports/FBgn0003281.html gene 16-Dec-15 2015_12 "male sterile,recessive,visible,eye color defective,fertile,good,viable,heat sensitive" "Malpighian tubule,pigment cell,ocellus pigment granule" FBgn0038211 CG9649 http://flybase.net/reports/FBgn0038211.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" "0022008=neurogenesis, 0006508=proteolysis" SP55 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG9649 16-Dec-15 2015_12 "ENSDARG00000068726(LOC100002060),ENSDARG00000007988(masp2)" "ENSMUSG00000027249(F2),ENSMUSG00000031444(F10),ENSMUSG00000059481(Plg),ENSMUSG00000024386(Proc),ENSMUSG00000031138(F9),ENSMUSG00000031443(F7)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0283438 CG46280 http://flybase.net/reports/FBgn0283438.html FBgn0038111 protein_coding_gene CG12360 "IPR002816=Pheromone shutdown, TraB" CG46280 16-Dec-15 2015_12 FBgn0259847 Su(Ste):CR42416 Su(Ste):CR42416 http://flybase.net/reports/FBgn0259847.html non_protein_coding_gene CR42416 CR42416 16-Dec-15 2015_12 FBgn0003319 Sb Stubble http://flybase.net/reports/FBgn0003319.html FBgn0010169 protein_coding_gene 0004252=serine-type endopeptidase activity "0016335=morphogenesis of larval imaginal disc epithelium, 0006508=proteolysis, 0051017=actin filament bundle assembly, 0035220=wing disc development, 0007010=cytoskeleton organization" "0016020=membrane, 0005886=plasma membrane" "sbd, stubbloid, st-sb, CG4316, c-SP56, Stubble-stubbloid, SP56, Sb-sbd" "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG4316 16-Dec-15 2015_12 "ENSDARG00000023111(plg),ENSDARG00000031855(mst1),ENSDARG00000063316,ENSDARG00000045544(hgfa)" ENSMUSG00000022857(Tmprss15) pupal stage " imaginal disc

, epidermis &&of leg | presumptive

, epidermis &&of wing | presumptive

" "visible,lethal,recessive,dominant,partially lethal - majority die,viable,poor,reduced,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,size defective" "chaeta,ventral thoracic disc,tibia,denticle belt,macrochaeta,ocellar bristle,metatarsus,leg,heat sensitive,adult thorax,dorsal,adult thorax & chaeta | conditional ts,prothoracic femur,microchaeta & actin filament,microchaeta & actin filamentsbd45),embryonic/first instar larval cuticle,anterior,wing vein L3,wing vein L4,anterior crossvein,wing,wing vein,ectopic,posterior crossvein" FBgn0034196 CG15605 http://flybase.net/reports/FBgn0034196.html FBgn0063310 protein_coding_gene BcDNA:AT23338 "IPR006575=RWD domain, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG15605 16-Dec-15 2015_12 viable FBgn0261907 Spc105R::Dwil\Spc105R http://flybase.net/reports/FBgn0261907.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0045495 Gr28b Gustatory receptor 28b http://flybase.net/reports/FBgn0045495.html "FBgn0031917, FBgn0041218, FBgn0045496" protein_coding_gene 0008527=taste receptor activity "0040040=thermosensory behavior, 0046957=negative phototaxis, 0007631=feeding behavior, 0006955=immune response, 0050909=sensory perception of taste, 0042742=defense response to bacterium, 0007602=phototransduction, 0035006=melanization defense response" 0016021=integral component of membrane "28A3, Gr28b.d, Gr28bB, Gr28A3, Gr28be, Gr28b.b, Gr28A4, Gr28bD, Gustatory receptor LU.2, GR28b, GrLU2, Gr28b.c, GRLU.2, GR28B, Gr28bE, Gustatory receptor 28A4, Gr28bC, Gr28b.e, LU.2, CG13788, gr28b, Gr28b.a, Gr28bA" IPR013604=7TM chemoreceptor CG13788 16-Dec-15 2015_12 "temperature response defective,viable,fertile,feeding behavior defective,long lived,immune response defective,conditional,neurophysiology defective" FBgn0085595 CG41279 http://flybase.net/reports/FBgn0085595.html FBan0041279 protein_coding_gene 16-Dec-15 2015_12 FBgn0031745 rau rau http://flybase.net/reports/FBgn0031745.html protein_coding_gene "0042803=protein homodimerization activity, 0017016=Ras GTPase binding" "0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0021782=glial cell development, 0045743=positive regulation of fibroblast growth factor receptor signaling pathway, 0045467=R7 cell development" CG8965 "IPR029071=Ubiquitin-related domain, IPR000159=Ras-associating (RA) domain" CG8965 16-Dec-15 2015_12 WBGene00012279(W05B10.4) "viable,fertile,male sterile" "eye,photoreceptor cell R7,embryonic/larval optic stalk surface glial cell,fascicle,photoreceptor cell R7 | third instar larval stage,supernumerary,fascicle | third instar larval stage" FBgn0051740 CG31740 http://flybase.net/reports/FBgn0051740.html "FBgn0045811, FBgn0063622, FBgn0063713" protein_coding_gene "BEST:GH22513, BcDNA:AT23551" CG31740 16-Dec-15 2015_12 viable FBgn0265849 CR44638 http://flybase.net/reports/FBgn0265849.html non_protein_coding_gene CR44638 16-Dec-15 2015_12 FBgn0041139 l(2)44Dc lethal (2) 44Dc http://flybase.net/reports/FBgn0041139.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260349 GSd314 http://flybase.net/reports/FBgn0260349.html gene 16-Dec-15 2015_12 lethal FBgn0005754 l(1)TK309 lethal (1) TK309 http://flybase.net/reports/FBgn0005754.html gene l309 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0011134 l(1)Q209 lethal (1) Q209 http://flybase.net/reports/FBgn0011134.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0028667 Vha16-3 Vacuolar H+ ATPase 16kD subunit 3 http://flybase.net/reports/FBgn0028667.html "FBgn0036163, FBgn0052090" protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "CG7547, Vacuolar H[+] ATPase subunit 16-3, CG32090, vha16-3, Vha16-3" "IPR002379=V-ATPase proteolipid subunit C-like domain, IPR000245=V-ATPase proteolipid subunit, IPR011555=V-ATPase proteolipid subunit C, eukaryotic" CG32090 16-Dec-15 2015_12 ENSDARG00000057853(atp6v0c) YEL027W(CUP5) WBGene00006912(vha-3) ENSXETG00000024442(atpv0c) ENSMUSG00000024121(Atp6v0c) ENSG00000185883(ATP6V0C) viable FBgn0050034 CG30034 http://flybase.net/reports/FBgn0050034.html protein_coding_gene 16-Dec-15 2015_12 viable FBgn0003426 slip slipshod http://flybase.net/reports/FBgn0003426.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic segment" FBgn0040784 karr karr http://flybase.net/reports/FBgn0040784.html protein_coding_gene 0007275=multicellular organismal development CG15323 CG15323 16-Dec-15 2015_12 "partially lethal - majority live,male limited,some die during larval stage,male fertile" FBgn0016978 snRNP-U1-70K small ribonucleoprotein particle U1 subunit 70K http://flybase.net/reports/FBgn0016978.html "FBgn0003458, FBgn0010508" protein_coding_gene "0030619=U1 snRNA binding, 0003723=RNA binding, 0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0048025=negative regulation of mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis, 0043484=regulation of RNA splicing, 0007052=mitotic spindle organization" "0005634=nucleus, 0005685=U1 snRNP, 0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0005692=U11 snRNP, 0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex" "Dm70K, snRNP27D, snRNP70K, U1-70K, U1 snRNP, U1snRNP-70K, U1 70k, l(2)02107, U1 70K, U1, dU1-70K, 70K, U1-70k, U1 70K snRNP, small nuclear ribonucleoprotein 70K, snRNP, U170K, U1 snRNP-specific 70K protein, CG8749" "IPR000504=RNA recognition motif domain, IPR022023=U1 small nuclear ribonucleoprotein of 70kDa N-terminal, IPR012677=Nucleotide-binding alpha-beta plait domain" CG8749 16-Dec-15 2015_12 ENSDARG00000037932(lin7b) YIL061C(SNP1) WBGene00004390(rnp-7) ENSXETG00000022919(snrp70) ENSMUSG00000063511(Snrnp70) ENSG00000104852(SNRNP70) "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0259536 GG01274 http://flybase.net/reports/FBgn0259536.html gene 16-Dec-15 2015_12 visible "wing,tarsal segment,unguis" FBgn0032228 CG5367 http://flybase.net/reports/FBgn0032228.html protein_coding_gene 0004197=cysteine-type endopeptidase activity 0006508=proteolysis "IPR013201=Cathepsin propeptide inhibitor domain (I29), IPR000668=Peptidase C1A, papain C-terminal, IPR013128=Peptidase C1A, IPR025660=Cysteine peptidase, histidine active site" CG5367 16-Dec-15 2015_12 "lethal,recessive,viable" FBgn0261429 CR42646 http://flybase.net/reports/FBgn0261429.html non_protein_coding_gene CR41445 CR42646 16-Dec-15 2015_12 FBgn0001586 l(1)carot3 lethal (1) carot3 http://flybase.net/reports/FBgn0001586.html gene "34, l(1)34, l34" 16-Dec-15 2015_12 "lethal,recessive" FBgn0262508 CG43078 http://flybase.net/reports/FBgn0262508.html "FBgn0052352, FBgn0035912, FBgn0035913, FBgn0052353, FBgn0052355" protein_coding_gene "CG32353, CG32352, lincRNA.473, CG32355, CG17926, CG6239" CG43078 16-Dec-15 2015_12 FBgn0266744 CR45217 http://flybase.net/reports/FBgn0266744.html non_protein_coding_gene CR45217 16-Dec-15 2015_12 FBgn0003713 tkd thickoid http://flybase.net/reports/FBgn0003713.html gene 16-Dec-15 2015_12 "partially lethal - majority live,fertile,large body" "wing,leg,eye,male genitalia" FBgn0027589 CG1688 http://flybase.net/reports/FBgn0027589.html "FBgn0043917, FBgn0043919, FBgn0043920, FBgn0043921, FBgn0043954" protein_coding_gene 0005267=potassium channel activity 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "anon-WO0109301.47, anon-WO0109301.12, anon-WO0109301.48, BcDNA:GH04802, anon-WO0109301.49, anon-WO0109301.50" "IPR003280=Two pore domain potassium channel, IPR013099=Potassium channel domain" CG1688 16-Dec-15 2015_12 ENSXETG00000004192(KCNK18) "ENSMUSG00000046410(Kcnk6),ENSMUSG00000033998(Kcnk1),ENSMUSG00000023387,ENSMUSG00000024957(Kcnk4)" "ENSG00000099337(KCNK6),ENSG00000135750(KCNK1),ENSG00000095981(KCNK16),ENSG00000173338(KCNK7)" "partially lethal - majority die,some die during pupal stage,viable" FBgn0065279 l(2)SH2041 lethal (2) SH2041 http://flybase.net/reports/FBgn0065279.html gene l(2)SH2 2041 16-Dec-15 2015_12 "lethal,recessive" FBgn0029131 Debcl Death executioner Bcl-2 homologue http://flybase.net/reports/FBgn0029131.html "FBgn0029509, FBgn0033080, FBgn0053134" protein_coding_gene "0043524=negative regulation of neuron apoptotic process, 0043066=negative regulation of apoptotic process, 0043067=regulation of programmed cell death, 0010623=developmental programmed cell death, 0009267=cellular response to starvation, 0035234=ectopic germ cell programmed cell death, 0046902=regulation of mitochondrial membrane permeability, 0006915=apoptotic process, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0060561=apoptotic process involved in morphogenesis, 0010212=response to ionizing radiation, 0070050=neuron cellular homeostasis, 0016239=positive regulation of macroautophagy, 0006914=autophagy" "0005741=mitochondrial outer membrane, 0005740=mitochondrial envelope, 0005739=mitochondrion" "dBORG-1/DROB-1/DEBCL/dBOK, debcl, debc1, debcl/Borg1, dBrog-1, dborg1, borg1/debcl, Bok, Drob-1/Debcl/dBorg-1/DBok, Drob-1/Debcl/dBorg-1/dBok, Debcl/dBorg-1/dBok/Drob-1, deborg, DBok, Drob-1/Debcl/dBORG-1, Drob-1, bcl-2, dBorg1, debok, dBok, Dbok, dbok/debcl, death inducing Bcl-2-like protein, CG33134, dbok, dBorg01, BG1, dBorg-1, death executioner Bcl-2 homologue, BOK, dBOK, Debcl, Debcl/Drob-1/dBorg-1/dBok, drob-1, CG12397, Bok(Debcl), Debcl/dBorg-1/dRob-1, DEBCL, Bcl-2" "IPR026309=Bcl-2-related ovarian killer protein, IPR026298=Blc2 family, IPR002475=Bcl2-like" CG33134 16-Dec-15 2015_12 "ENSDARG00000052129(boka),ENSDARG00000008807(bokb)" "ENSXETG00000025175(BCL2L1),ENSXETG00000014599(bcl2l2),ENSXETG00000024124(BCL2)" ENSMUSG00000026278(Bok) ENSG00000176720(BOK) " larval stage | third instar , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | early , embryonic stage | stage 11 , embryonic stage | stage 14-16 , embryonic stage | stage 5 " " brain | resticted

, oocyte

, eye disc

, posterior midgut proper primordium

, ventral thoracic disc

, eye-antennal disc | resticted

, nurse cell

, dorsal mesothoracic disc

, embryonic/larval midgut

,

ubiquitous , proctodeum

, embryonic head segment | restricted

, embryonic/larval salivary gland duct

" "viable,fertile,radiation sensitive,decreased cell death,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,short lived,locomotor behavior defective,conditional,cell death defective,increased cell death,long lived,visible,neuroanatomy defective,somatic clone" "wing margin,conditional,scutellar bristle,supernumerary,male genitalia,vagina,maxillary palpus,tergite,sternite,melanotic mass,ventral nerve cord,Bolwig organ,midline glial cell,central nervous system,ectopic,eye,pigment cell,interommatidial bristle,eye photoreceptor cell,ommatidium,eye disc,posterior,wing,salivary gland,mitochondrion & dorsal multidendritic neuron ddaCppk.1.9,dendrite & dorsal multidendritic neuron ddaC | somatic cloneppk.1.9,dendrite & class IV dendritic arborising neuronppk.1.9,dendrite & abdominal anterior ventral multidendritic neuron vdaappk.1.9" FBgn0014342 mia meiosis I arrest http://flybase.net/reports/FBgn0014342.html FBgn0037337 protein_coding_gene 0046982=protein heterodimerization activity "0048515=spermatid differentiation, 0007283=spermatogenesis, 0007126=meiotic nuclear division, 0006367=transcription initiation from RNA polymerase II promoter, 0007286=spermatid development, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0007141=male meiosis I, 0010468=regulation of gene expression" "0005669=transcription factor TFIID complex, 0005730=nucleolus, 0001673=male germ cell nucleus" "TAF60-2, TFIID, dTAF[[II]]60-2, ms(3)570, dmTAF6b, TBP-associated factor 6-like, Taf6L, dTAF[[II]]60, dTAF6L, CG10390, Meiosis I arrest, TAF6L, TAF[[II]]60-2, TAF[[II]], TBP-associated factor 60kD-2, Mia, Taf60-2, TAF6-like, TAF" "IPR011989=Armadillo-like helical, IPR009072=Histone-fold, IPR011442=TAF6, C-terminal HEAT repeat domain" CG10390 16-Dec-15 2015_12 WBGene00006387(taf-6.1) "viable,fertile,male sterile,recessive" "testis,spermatocyte" FBgn0060767 l(3)S062314 lethal (3) S062314 http://flybase.net/reports/FBgn0060767.html gene 0623/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0265143 CR44212 http://flybase.net/reports/FBgn0265143.html non_protein_coding_gene CR44212 16-Dec-15 2015_12 FBgn0084049 CR41440 http://flybase.net/reports/FBgn0084049.html "FBan0041440, FBgn0058287" pseudogene_attribute CG40287 CR41440 16-Dec-15 2015_12 FBgn0032240 CG17768 http://flybase.net/reports/FBgn0032240.html "FBgn0032241, FBgn0051990, FBgn0064888, FBtr0080048, FBpp0079638, FBtr0080049, FBpp0079639" protein_coding_gene 0017070=U6 snRNA binding "0000398=mRNA splicing, via spliceosome" 0046540=U4/U6 x U5 tri-snRNP complex "CG5356, BcDNA:RE35747, CG31990" "IPR010920=LSM domain, IPR027141=Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3, IPR001163=LSM domain, eukaryotic/archaea-type" CG17768 16-Dec-15 2015_12 ENSDARG00000023852(lsm4) YER112W(LSM4) WBGene00003078(lsm-4) ENSXETG00000024933(lsm4) ENSMUSG00000031848(Lsm4) ENSG00000130520(LSM4) DRSC02845 E -0.548537209 -0.021259324 -0.76578505 1.738559685 -0.873071949 0.149291831 FBgn0029994 CG2254 http://flybase.net/reports/FBgn0029994.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process 0005811=lipid particle "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR002347=Glucose/ribitol dehydrogenase" CG2254 16-Dec-15 2015_12 "YDL114W(),YLR426W()" viable FBgn0036039 Naa60 N(alpha)-acetyltransferase 60 http://flybase.net/reports/FBgn0036039.html protein_coding_gene "0004402=histone acetyltransferase activity, 0004596=peptide alpha-N-acetyltransferase activity, 0010485=H4 histone acetyltransferase activity" "0007059=chromosome segregation, 0043967=histone H4 acetylation, 0017196=N-terminal peptidyl-methionine acetylation" 0005737=cytoplasm "NAA60, Hat4, CG18177, NatF, dNAA60, dNaa60, dNatF, DmAAF50213" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG18177 16-Dec-15 2015_12 ENSDARG00000061185(nat15) WBGene00009277(F30F8.10) ENSMUSG00000005982(Nat15) ENSG00000122390(NAA60) viable FBgn0043041 l(2)42Ab lethal (2) 42Ab http://flybase.net/reports/FBgn0043041.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0260004 Snmp1 Sensory neuron membrane protein 1 http://flybase.net/reports/FBgn0260004.html "FBgn0259485, FBgn0038867" protein_coding_gene 0005044=scavenger receptor activity "0007166=cell surface receptor signaling pathway, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0055088=lipid homeostasis, 0007155=cell adhesion, 0006952=defense response, 0035073=pupariation, 0019236=response to pheromone" "0005887=integral component of plasma membrane, 0043025=neuronal cell body, 0030425=dendrite, 0016020=membrane" "SNMP1, Sensory Neuron Membrane Protein, CG7000, sensory neuron membrane protein, Snmp, snmp1, Sensory neuron membrane protein, snmp, SNMP" "IPR002159=CD36 antigen, IPR005428=Adhesion molecule CD36" CG7000 16-Dec-15 2015_12 FBgn0030058 CG11294 http://flybase.net/reports/FBgn0030058.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus CT31519 "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG11294 16-Dec-15 2015_12 "ENSDARG00000009922(dmbx1a),ENSDARG00000002510" "ENSMUSG00000021848(Otx2),ENSMUSG00000041578(Crx)" "ENSG00000165588(OTX2),ENSG00000115507(OTX1),ENSG00000105392(CRX)" lethal DRSC17777 K -0.411349728 -0.018532853 0.471724701 0.604063744 2.537995597 0.883912606 FBgn0037834 Art1 Arginine methyltransferase 1 http://flybase.net/reports/FBgn0037834.html protein_coding_gene "0035241=protein-arginine omega-N monomethyltransferase activity, 0044020=histone methyltransferase activity (H4-R3 specific), 0016274=protein-arginine N-methyltransferase activity, 0035242=protein-arginine omega-N asymmetric methyltransferase activity, 0042054=histone methyltransferase activity" "0016571=histone methylation, 0019919=peptidyl-arginine methylation, to asymmetrical-dimethyl arginine, 0043985=histone H4-R3 methylation" "dart1, DART1, CG6554, arginine methyltransferase 1, Dart, Arg methyltransferase 1" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025799=Protein arginine N-methyltransferase" CG6554 16-Dec-15 2015_12 "ENSDARG00000010246(prmt1),ENSDARG00000040633,ENSDARG00000045760(prmt8b)" YBR034C(HMT1) WBGene00013766(prmt-1) "ENSXETG00000002877(hrmt1l2),ENSXETG00000016651(PRMT8)" "ENSMUSG00000052429(Prmt1),ENSMUSG00000030350(Prmt8)" "ENSG00000126457(PRMT1),ENSG00000111218(PRMT8)" "developmental rate defective,recessive,visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,viable,partially lethal" posterior crossvein FBgn0263877 D76 http://flybase.net/reports/FBgn0263877.html gene 16-Dec-15 2015_12 "decreased cell number,somatic clone" "embryonic/larval neuroblast,somatic clone,embryonic/larval brain" FBgn0044872 FucTC FucTC http://flybase.net/reports/FBgn0044872.html "FBan0040305, FBgn0058305" protein_coding_gene "0008417=fucosyltransferase activity, 0046920=alpha-(1->3)-fucosyltransferase activity" 0006486=protein glycosylation "0016020=membrane, 0005886=plasma membrane" "CG40305, alpha1,3-fucosyltransferase" IPR001503=Glycosyl transferase family 10 CG40305 16-Dec-15 2015_12 WBGene00001505(fut-1) "ENSMUSG00000036587(Fut7),ENSMUSG00000049307(Fut4),ENSMUSG00000055373(Fut9)" FBgn0052861 snRNA:U4atac:83A snRNA:U4atac:83A http://flybase.net/reports/FBgn0052861.html snRNA_gene CR32861 16-Dec-15 2015_12 FBgn0037015 cmpy crimpy http://flybase.net/reports/FBgn0037015.html protein_coding_gene "0005520=insulin-like growth factor binding, 0005515=protein binding" "0007528=neuromuscular junction development, 0038056=negative regulation of BMP signaling pathway by negative regulation of BMP secretion, 0001558=regulation of cell growth, 0030514=negative regulation of BMP signaling pathway" 0005576=extracellular region CG13253 "IPR011390=Insulin-like growth factor binding protein-related protein (IGFBP-rP), MAC25, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000867=Insulin-like growth factor-binding protein, IGFBP" CG13253 16-Dec-15 2015_12 "viable,female sterile,recessive,neuroanatomy defective" "type I bouton,supernumerary,supernumerary | third instar larval stage,type I bouton | third instar larval stage" FBgn0038756 CG4783 http://flybase.net/reports/FBgn0038756.html protein_coding_gene GH26202 CG4783 16-Dec-15 2015_12 viable FBgn0046628 anon-AE003550.1 anon-AE003550.1 http://flybase.net/reports/FBgn0046628.html gene unnamed 16-Dec-15 2015_12 FBgn0060578 l(3)S095204b lethal (3) S095204b http://flybase.net/reports/FBgn0060578.html gene 0952/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0063908 Neurodegeneration-11 Neurodegeneration 11 http://flybase.net/reports/FBgn0063908.html gene ND11 16-Dec-15 2015_12 central nervous system FBgn0037153 olf413 olf413 http://flybase.net/reports/FBgn0037153.html "FBgn0037154, FBgn0037155, FBgn0053185" protein_coding_gene "0005507=copper ion binding, 0004500=dopamine beta-monooxygenase activity" 0055114=oxidation-reduction process "0005615=extracellular space, 0005829=cytosol" "CG14461, CG12673, CG7495, Olf413, CR33185" "IPR024548=Copper type II ascorbate-dependent monooxygenase, C-terminal, IPR005018=DOMON domain, IPR008977=PHM/PNGase F domain, IPR000945=Dopamine beta-hydroxylase-related, IPR014784=Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR000323=Copper type II, ascorbate-dependent monooxygenase, N-terminal" CG12673 16-Dec-15 2015_12 ENSXETG00000011974(MOXD1) DRSC11833 EK -0.70812888 -0.193917478 1.990539255 0.209447807 2.0015963 0.41620867 FBgn0035285 CG12025 http://flybase.net/reports/FBgn0035285.html protein_coding_gene "IPR008590=Protein of unknown function DUF872, transmembrane" CG12025 16-Dec-15 2015_12 ENSMUSG00000024845(Tmem134) ENSG00000172663(TMEM134) viable DRSC08230 K -0.329521731 0.54658605 0.29287442 0.923480631 -1.025185482 1.601113619 FBgn0036610 CG13058 http://flybase.net/reports/FBgn0036610.html protein_coding_gene CG13058 16-Dec-15 2015_12 viable DRSC27898 K 0.506108483 0.295712528 -0.190027776 -0.021719054 0.399866532 1.67877551 FBgn0053436 5SrRNA:CR33436 5SrRNA:CR33436 http://flybase.net/reports/FBgn0053436.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33436 CR33436 16-Dec-15 2015_12 FBgn0264464 CR43872 http://flybase.net/reports/FBgn0264464.html non_protein_coding_gene CG43872 CR43872 16-Dec-15 2015_12 FBgn0039312 CG10514 http://flybase.net/reports/FBgn0039312.html protein_coding_gene CT29508 "IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227" CG10514 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0005111 l(1)3C3 lethal (1) 3C3 http://flybase.net/reports/FBgn0005111.html gene 16-Dec-15 2015_12 FBgn0000100 RpLP0 Ribosomal protein LP0 http://flybase.net/reports/FBgn0000100.html FBgn0010752 protein_coding_gene "0003735=structural constituent of ribosome, 0003906=DNA-(apurinic or apyrimidinic site) lyase activity" "0042254=ribosome biogenesis, 0006281=DNA repair, 0006412=translation" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit, 0005737=cytoplasm, 0005634=nucleus" "ACIDIC RIBOSOMAL PROTEIN LP0, 60S ribosomal protein P0, Apurinic endonuclease 3, l(3)0154, Ape, p0, PO, Ribosomal protein P0, RpP0, LP0, Rplp0, l(3)01544, RLA0, CG7490, Ap3, RPL P0, ribosomal protein P0, P0, AP3, P35, RpPO" "IPR001790=Ribosomal protein L10P, IPR030670=60S acidic ribosomal protein P0" CG7490 16-Dec-15 2015_12 ENSDARG00000051783(rplp0) YLR340W(RPP0) WBGene00004408(rla-0) ENSXETG00000026942(rplp0) ENSMUSG00000067274(Rplp0) ENSG00000089157(RPLP0) "lethal,recessive,suppressor of variegation,dominant,non-suppressor of variegation,wild-type" DRSC22110 IEK -0.366955874 -1.517568525 2.914994774 -3.874587585 2.093225315 4.288150414 FBgn0000279 CecC Cecropin C http://flybase.net/reports/FBgn0000279.html FBgn0062945 protein_coding_gene "0019731=antibacterial humoral response, 0050832=defense response to fungus, 0042742=defense response to bacterium, 0050829=defense response to Gram-negative bacterium, 0050830=defense response to Gram-positive bacterium, 0006959=humoral immune response" "0005576=extracellular region, 0005615=extracellular space" "cecropin C, BcDNA:RH33561, cecropin, cecC, Cec, Cecropin-C, Cec-C, CG1373, cec, Cecropin-C precursor, Cecropin" "IPR020400=Cecropin, diptera, IPR000875=Cecropin" CG1373 16-Dec-15 2015_12 FBgn0001335 l(1)1Ad lethal (1) 1Ad http://flybase.net/reports/FBgn0001335.html gene "lEC2, l(1)EC2, EC2, l(1)2804, l[EC2]" 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0010214 Prl Proxless http://flybase.net/reports/FBgn0010214.html gene 16-Dec-15 2015_12 visible "costal cell,wing vein L2,wing vein L5,wing vein L6,alula,anterior crossvein,posterior crossvein" FBgn0031308 CG4749 http://flybase.net/reports/FBgn0031308.html FBgn0061625 protein_coding_gene 0008168=methyltransferase activity anon-WO0118547.81 "IPR023267=RNA (C5-cytosine) methyltransferase, IPR001678=SAM-dependent methyltransferase RsmB/NOP2-type, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG4749 16-Dec-15 2015_12 ENSDARG00000021324(nsun4) WBGene00021476(Y39G10AR.21) ENSXETG00000024501(nsun4) ENSMUSG00000028706(Nsun4) ENSG00000117481(NSUN4) viable FBgn0011852 tRNA:E4:62Ab transfer RNA:glu4:62Ab http://flybase.net/reports/FBgn0011852.html "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052326, FBgn0060249" tRNA_gene "0033460=GAG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr3L.trna7-GluCTC, tRNA:glu4:62Ab, CR32326, tRNA:E4, AE002584.trna7-GluCTC, tRNA:Glu, tRNA:E:CTC:AE002584-e" CR32326 16-Dec-15 2015_12 FBgn0010125 l(1)M1 lethal (1) M1 http://flybase.net/reports/FBgn0010125.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0010147 l(3)96Fe lethal (3) 96Fe http://flybase.net/reports/FBgn0010147.html gene l(3)B128 16-Dec-15 2015_12 "lethal,recessive" FBgn0032632 CG6380 http://flybase.net/reports/FBgn0032632.html protein_coding_gene 0004864=protein phosphatase inhibitor activity "0043666=regulation of phosphoprotein phosphatase activity, 0009966=regulation of signal transduction" IPR007062=Protein phosphatase inhibitor 2 (IPP-2) CG6380 16-Dec-15 2015_12 viable FBgn0266182 CR44888 http://flybase.net/reports/FBgn0266182.html non_protein_coding_gene CR44888 16-Dec-15 2015_12 FBgn0266115 CR44841 http://flybase.net/reports/FBgn0266115.html non_protein_coding_gene CR44841 16-Dec-15 2015_12 FBgn0040376 CG13759 http://flybase.net/reports/FBgn0040376.html "FBgn0029624, FBgn0061449" protein_coding_gene 0008080=N-acetyltransferase activity "EG:BACR25B3.5, BcDNA:AT19803, CT33239" IPR016181=Acyl-CoA N-acyltransferase CG13759 16-Dec-15 2015_12 "WBGene00010887(M7.12),WBGene00010884(M7.8),WBGene00011046(R05H10.7),WBGene00020940(W02D7.4),WBGene00020941(W02D7.5),WBGene00011042(R05H10.1)" FBgn0025613 CG3081 http://flybase.net/reports/FBgn0025613.html protein_coding_gene EG:84H4.4 CG3081 16-Dec-15 2015_12 viable FBgn0035792 CG7548 http://flybase.net/reports/FBgn0035792.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle IPR022727=Pupal cuticle protein C1 CG7548 16-Dec-15 2015_12 viable DRSC29043 K 0.377572115 0.706384869 0.503823625 0.038220683 -0.852142161 -4.992974036 FBgn0038926 CG13409 http://flybase.net/reports/FBgn0038926.html protein_coding_gene CG13409 16-Dec-15 2015_12 ENSDARG00000045910(si:ch211-51e12.4) ENSXETG00000023341(TEgg001l15.1) ENSMUSG00000038141(Tmem181a) ENSG00000146433(TMEM181) viable FBgn0012010 tRNA:V4:70BCb transfer RNA:val4:70BCb http://flybase.net/reports/FBgn0012010.html "FBgn0003858, FBgn0012007, FBgn0052124, FBgn0060031" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033449=GUU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA-Val-4, tRNA[Val][[4]], tRNA:V:AAC:AE002602-b, chr3L.trna27-ValAAC, AE002602.trna22-ValAAC, valine tRNA, val-tRNA-4, CR32124, tRNA[Val-AAC], tRNA:val4:70BCb, tRNA:V4" CR32124 16-Dec-15 2015_12 FBgn0030372 CG12722 http://flybase.net/reports/FBgn0030372.html protein_coding_gene 16-Dec-15 2015_12 FBgn0065695 l(2)SH0637 lethal (2) SH0637 http://flybase.net/reports/FBgn0065695.html gene l(2)SH2 0637 16-Dec-15 2015_12 "lethal,recessive" FBgn0033303 Cyp6a15ë¬ Cyp6a15ë¬ http://flybase.net/reports/FBgn0033303.html pseudogene_attribute "Cyp6a15p, CG14753, CR14753, 6a15p" CR14753 16-Dec-15 2015_12 DRSC07377 E -0.515407516 0.18445392 0.340902742 2.080053596 0.144111646 1.39981789 FBgn0039184 CG6432 http://flybase.net/reports/FBgn0039184.html protein_coding_gene 0003987=acetate-CoA ligase activity 0008152=metabolic process "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase" CG6432 16-Dec-15 2015_12 ENSDARG00000032218(acss3) ENSXETG00000014528(ACSS3) ENSMUSG00000035948(Acss3) ENSG00000111058(ACSS3) viable FBgn0030053 CG12081 http://flybase.net/reports/FBgn0030053.html protein_coding_gene 0003682=chromatin binding 0000790=nuclear chromatin "IPR011043=Galactose oxidase/kelch, beta-propeller, IPR015916=Galactose oxidase, beta-propeller, IPR006652=Kelch repeat type 1" CG12081 16-Dec-15 2015_12 ENSDARG00000039840(zgc:91813) WBGene00009978(F53E4.1) ENSXETG00000000566(KLHDC3) ENSMUSG00000063576(Klhdc3) ENSG00000124702(KLHDC3) viable FBgn0024840 rK(2)639 rK(2)639 http://flybase.net/reports/FBgn0024840.html gene 16-Dec-15 2015_12 FBgn0058224 CG40224 http://flybase.net/reports/FBgn0058224.html protein_coding_gene 16-Dec-15 2015_12 FBgn0001043 fs(3)HO29 female sterile (3) HO29 http://flybase.net/reports/FBgn0001043.html gene fs(3)29A 16-Dec-15 2015_12 female sterile "oocyte,ovary" FBgn0266854 CR45315 http://flybase.net/reports/FBgn0266854.html pseudogene_attribute CR45315 16-Dec-15 2015_12 FBgn0003607 Su(var)205 Suppressor of variegation 205 http://flybase.net/reports/FBgn0003607.html protein_coding_gene "0042393=histone binding, 0003729=mRNA binding, 0003696=satellite DNA binding, 0035064=methylated histone binding, 0000182=rDNA binding, 0005515=protein binding, 0003682=chromatin binding, 0003723=RNA binding" "0045892=negative regulation of transcription, DNA-templated, 0033697=positive regulation of extent of heterochromatin assembly, 0051276=chromosome organization, 0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis, 0044026=DNA hypermethylation, 0006343=establishment of chromatin silencing, 0034773=histone H4-K20 trimethylation, 0042981=regulation of apoptotic process, 0000723=telomere maintenance, 0006342=chromatin silencing, 0016458=gene silencing, 0031507=heterochromatin assembly, 0045893=positive regulation of transcription, DNA-templated, 0031060=regulation of histone methylation, 0030702=chromatin silencing at centromere, 1900111=positive regulation of histone H3-K9 dimethylation" "0000780=condensed nuclear chromosome, centromeric region, 0035012=polytene chromosome, telomeric region, 0005634=nucleus, 0005694=chromosome, 0000781=chromosome, telomeric region, 0005701=polytene chromosome chromocenter, 0005720=nuclear heterochromatin, 0005700=polytene chromosome, 0000792=heterochromatin, 0000791=euchromatin, 0000793=condensed chromosome, 0005703=polytene chromosome puff, 0005721=pericentric heterochromatin, 0005704=polytene chromosome band, 0000775=chromosome, centromeric region" "Hp1, Su(Var)2-5, su(var)205, E(var)29A, HP-1, heterochromatic protein, heterochromatin-protein-1, C1A9-nuclear-antigen, Su(var)2-05, hp1, Su(var)2-501, SU(VAR)205, Su(var)205, Heterochromatin protein-1, heterochromatin protein-1, Heterochromatin protein 1A, Heterochromatic Protein 1a, Su-var(2)5, Suvar2-5, dHP1, Heterochromatin Protein 1a, Heterochromatin protein 1, Su[var]205, suppressor of variegated 205, Su(var)[205], Hp1a, heterochromatin-binding protein, Histone Protein 1, Heterochromatin Protein 1A, hp1a, HP1-VS, Su(var)2-5, Heterochromatin Protein 1, Su(var), CBX5, E(var)29, Suvar(2)5, heterochromatin protein 1, CG8409, FBgn0003607, dHP-1a, DmHP-1, HP1A, DmHP1, HP1, Su[Var]205, Su(var)29A, HP1alpha, heterochromatin protein 1a, HP1a, Suppressor of variegation 205" "IPR023780=Chromo domain, IPR023779=Chromo domain, conserved site, IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR008251=Chromo shadow domain, IPR017984=Chromo domain subgroup" CG8409 16-Dec-15 2015_12 ENSDARG00000061187(cbx5) WBGene00001995(hpl-1) adult stage larval stage larval salivary gland

"lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,wild-type,non-enhancer of variegation,suppressor of variegation,recessive,dominant,non-suppressor of variegation,lethal,increased cell death,neuroanatomy defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,female sterile" "wing,posterior,wing disc,eye disc,eye,neuroblast,neuroblast & larval brain,polytene chromosome2055),chromosome, telomeric region2055),mitosis & nuclear chromosome2055),imaginal disc,polytene chromosome | male2055),meiosis & nuclear chromosome | male,chromosome, telomeric region,melanotic mass,mitosis & chromosome, telomeric region,prothoracic gland,gastric caecum,embryonic/larval optic lobe,chromosome, telomeric region2054),mitosis & nuclear chromosome2054),polytene chromosome2054),polytene chromosome | male2054),polytene chromosome20503),mitotic cell cycle, with Su(var)205a.cDLa,mitotic cell cycle, with Su(var)205cDLa,polytene chromosome,embryonic/larval neuroblast,ganglion mother cell" FBgn0001765 l(1)M25 lethal (1) M25 http://flybase.net/reports/FBgn0001765.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0021920 l(2)k11303 lethal (2) k11303 http://flybase.net/reports/FBgn0021920.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0032130 CG3838 http://flybase.net/reports/FBgn0032130.html "FBgn0045353, FBgn0061998" protein_coding_gene 0003677=DNA binding "anon-WO0118547.445, NEST:bs09e08, bs09e08.y1" "IPR004210=BESS motif, IPR006578=MADF domain" CG3838 16-Dec-15 2015_12 viable FBgn0035591 CG4611 http://flybase.net/reports/FBgn0035591.html protein_coding_gene IPR002885=Pentatricopeptide repeat CG4611 16-Dec-15 2015_12 ENSXETG00000009891() ENSMUSG00000029624(Ptcd1) ENSG00000106246(PTCD1) "viable,visible" trichogen cell FBgn0266201 CR44896 http://flybase.net/reports/FBgn0266201.html non_protein_coding_gene CR44896 16-Dec-15 2015_12 FBgn0067784 arr::fz2 arr::fz2 http://flybase.net/reports/FBgn0067784.html engineered_fusion_gene 16-Dec-15 2015_12 "wing vein,ectopic,wing margin bristle,denticle row 3,denticle row 4,denticle row 5,denticle row 6" FBgn0267881 CR46169 http://flybase.net/reports/FBgn0267881.html pseudogene_attribute Mst35Ba-related CR46169 16-Dec-15 2015_12 FBgn0031313 CG5080 http://flybase.net/reports/FBgn0031313.html protein_coding_gene 0005886=plasma membrane CT16297 CG5080 16-Dec-15 2015_12 FBgn0065860 l(2)SH0277 lethal (2) SH0277 http://flybase.net/reports/FBgn0065860.html gene l(2)SH2 0277 16-Dec-15 2015_12 "lethal,recessive" FBgn0014279 oho51 overgrown hematopoietic organs 51 http://flybase.net/reports/FBgn0014279.html FBgn0016987 gene 0048542=lymph gland development "l(2)k21105, l(2)211/5, l(2)211/15" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0061102 l(3)S008806b lethal (3) S008806b http://flybase.net/reports/FBgn0061102.html gene 0088/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0024755 EP2585 EP2585 http://flybase.net/reports/FBgn0024755.html gene 16-Dec-15 2015_12 FBgn0066374 arl arleekin http://flybase.net/reports/FBgn0066374.html gene "0007611=learning or memory, 0008355=olfactory learning" Arleekin 16-Dec-15 2015_12 memory defective FBgn0044353 Quasimodo\gag gag http://flybase.net/reports/FBgn0044353.html transposable_element_gene cruiser\gag 16-Dec-15 2015_12 FBgn0039219 CG13630 http://flybase.net/reports/FBgn0039219.html protein_coding_gene "0008235=metalloexopeptidase activity, 0004177=aminopeptidase activity" 0006508=proteolysis MAP1A "IPR001714=Peptidase M24, methionine aminopeptidase, IPR000994=Peptidase M24, structural domain, IPR002467=Peptidase M24A, methionine aminopeptidase, subfamily 1" CG13630 16-Dec-15 2015_12 ENSDARG00000033440(metap1) YLR244C(MAP1) WBGene00003129(map-1) ENSXETG00000009315(METAP1) ENSMUSG00000005813(Metap1) ENSG00000164024(METAP1) FBgn0002498 l(3)SG59 lethal (3) SG59 http://flybase.net/reports/FBgn0002498.html gene 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0263541 mir-4986 mir-4986 stem loop http://flybase.net/reports/FBgn0263541.html miRNA_gene "CR43526, dme-mir-4986" CR43526 16-Dec-15 2015_12 FBgn0260749 Utx Utx histone demethylase http://flybase.net/reports/FBgn0260749.html "FBgn0032207, FBgn0015865" protein_coding_gene "0001047=core promoter binding, 0071558=histone demethylase activity (H3-K27 specific), 0032452=histone demethylase activity, 0005515=protein binding" "0045893=positive regulation of transcription, DNA-templated, 0071480=cellular response to gamma radiation, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0045746=negative regulation of Notch signaling pathway, 0071390=cellular response to ecdysone, 0071557=histone H3-K27 demethylation, 1990248=regulation of transcription from RNA polymerase II promoter in response to DNA damage, 0061086=negative regulation of histone H3-K27 methylation, 0010508=positive regulation of autophagy, 0045498=sex comb development, 1902465=negative regulation of histone H3-K27 trimethylation, 0042060=wound healing, 0016577=histone demethylation, 0035078=induction of programmed cell death by ecdysone, 0008285=negative regulation of cell proliferation, 0051568=histone H3-K4 methylation" "0044666=MLL3/4 complex, 0005705=polytene chromosome interband, 0005700=polytene chromosome, 0035327=transcriptionally active chromatin, 0005634=nucleus" "anon-31BCa, utx, UTX, CG5640, dUtx, dUTX" "IPR013026=Tetratricopeptide repeat-containing domain, IPR001440=Tetratricopeptide repeat 1, IPR019734=Tetratricopeptide repeat, IPR003347=JmjC domain, IPR011990=Tetratricopeptide-like helical domain" CG5640 16-Dec-15 2015_12 "ENSDARG00000061759,ENSDARG00000059794(kdm6al)" WBGene00017046(utx-1) ENSXETG00000004822() "ENSMUSG00000037369(Kdm6a),ENSMUSG00000068457(Uty)" "ENSG00000147050(KDM6A),ENSG00000183878(UTY)" DRSC02872 I 0.98005238 1.6028577 0.172204273 1.073779263 0.070810418 0.419056625 FBgn0028634 ifm(2)RU8 indirect flight muscle (2) RU8 http://flybase.net/reports/FBgn0028634.html gene 0007517=muscle organ development 0005703=polytene chromosome puff 16-Dec-15 2015_12 "visible,recessive,flight defective,viable" "wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0067768 grl gerlache http://flybase.net/reports/FBgn0067768.html gene 0045450=bicoid mRNA localization 16-Dec-15 2015_12 female sterile "egg chamber,germline clone,egg" FBgn0017393 l(1)10Bt lethal (1) 10Bt http://flybase.net/reports/FBgn0017393.html gene HM416 16-Dec-15 2015_12 "lethal,recessive" FBgn0029828 CG6067 http://flybase.net/reports/FBgn0029828.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG6067 16-Dec-15 2015_12 viable FBgn0039498 CG17991 http://flybase.net/reports/FBgn0039498.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination "0005789=endoplasmic reticulum membrane, 0005741=mitochondrial outer membrane" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011016=Zinc finger, RING-CH-type" CG17991 16-Dec-15 2015_12 viable DRSC15294 E -0.712540775 -0.010846381 -2.085254885 0.499660178 0.352392115 -0.411384865 FBgn0267089 CR45533 http://flybase.net/reports/FBgn0267089.html non_protein_coding_gene CR45533 16-Dec-15 2015_12 FBgn0029856 CG11700 http://flybase.net/reports/FBgn0029856.html FBgn0052744 protein_coding_gene 0031386=protein tag "2000242=negative regulation of reproductive process, 0008340=determination of adult lifespan, 0016567=protein ubiquitination" 0005875=microtubule associated complex "CG11700, anon-sts41, poly-ub, Ubiquitin, ESTS:199A6T, ESTS:143G11T, ubiquitin, Ubi-p5E5, CR11700" "IPR019954=Ubiquitin conserved site, IPR000626=Ubiquitin domain, IPR019956=Ubiquitin, IPR029071=Ubiquitin-related domain" CG11700 16-Dec-15 2015_12 "viable,short lived,male" DRSC17794 IEK -2.64849259 -0.379170482 13.06703615 -3.640441366 -6.451732882 -2.769467211 FBgn0058269 CG40269 http://flybase.net/reports/FBgn0058269.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002688 mbmB mushroom body miniature B http://flybase.net/reports/FBgn0002688.html gene 0016319=mushroom body development "rem, mushroom-body-miniature-B, mbmB[N806], reduced-mushroom-bodies, mbm[B]" 16-Dec-15 2015_12 "female sterile,behavior defective,locomotor behavior defective,female limited,partially lethal - majority die" "ellipsoid body,nodulus,adult central complex,calyx of larval mushroom body,lobe system of adult mushroom body,adult mushroom body,calyx of adult mushroom body" FBgn0028200 l(3)S019203 lethal (3) S019203 http://flybase.net/reports/FBgn0028200.html gene "0192/03, 0955/15, 1003/03, 0019/06, 1026/09, 1367/03, 1232/13, l(3)S141715, 0281/08, 1426/01, 1145/13, 0229/11, 1417/15" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0025592 Gyk Glycerol kinase http://flybase.net/reports/FBgn0025592.html FBgn0035108 protein_coding_gene 0004370=glycerol kinase activity "0005975=carbohydrate metabolic process, 0046167=glycerol-3-phosphate biosynthetic process" "glycerol kinase, dGyk, CG18374" "IPR005999=Glycerol kinase, IPR018485=Carbohydrate kinase, FGGY, C-terminal, IPR000577=Carbohydrate kinase, FGGY, IPR018484=Carbohydrate kinase, FGGY, N-terminal, IPR018483=Carbohydrate kinase, FGGY, conserved site" CG18374 16-Dec-15 2015_12 ENSDARG00000053456(zgc:172295) YHL032C(GUT1) WBGene00020007(R11F4.1) ENSXETG00000018610() "ENSMUSG00000050553(Gk2),ENSMUSG00000025059(Gyk),ENSMUSG00000053624(Gykl1)" "ENSG00000196475(GK2),ENSG00000198814(GK)" "chemical sensitive,fertile,recessive" DRSC08534 K 0.544527395 -1.37606805 0.10335999 0.099666296 -0.264762194 2.158484 FBgn0026756 Ugt37a1 UDP-glycosyltransferase 37a1 http://flybase.net/reports/FBgn0026756.html FBgn0032855 protein_coding_gene "0016758=transferase activity, transferring hexosyl groups, 0008194=UDP-glycosyltransferase activity" 0006011=UDP-glucose metabolic process 0016021=integral component of membrane "38C.41, CG11012, DmUgt37a1, DmeUgt37a1" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG11012 16-Dec-15 2015_12 "WBGene00007073(ugt-2),WBGene00007072(ugt-1),WBGene00013903(ugt-3),WBGene00020592(ugt-12),WBGene00020594(ugt-10),WBGene00020593(ugt-11),WBGene00020587(ugt-9),WBGene00019234(ugt-8),WBGene00019232(ugt-13),WBGene00019235(H23N18.4),WBGene00019233(ugt-14)" viable FBgn0061090 l(3)S011406 lethal (3) S011406 http://flybase.net/reports/FBgn0061090.html gene 0114/06 16-Dec-15 2015_12 "lethal,recessive" FBgn0026238 gus gustavus http://flybase.net/reports/FBgn0026238.html "FBan0002944, FBgn0033008, FBgn0033009" protein_coding_gene 0005515=protein binding "0007281=germ cell development, 0007314=oocyte anterior/posterior axis specification, 0035556=intracellular signal transduction, 0046843=dorsal appendage formation, 0045732=positive regulation of protein catabolic process" "0005938=cell cortex, 0005634=nucleus, 0031466=Cul5-RING ubiquitin ligase complex, 0045495=pole plasm, 0005737=cytoplasm" "i25, A11, GUS, CG2946, dmSSB4, GUSTAVUS, Gustavus, CG2944, Gus" "IPR003877=SPRY domain, IPR001870=B30.2/SPRY domain, IPR001496=SOCS box domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG2944 16-Dec-15 2015_12 ENSDARG00000056515(spsb1) WBGene00021596(spsb-2) "ENSXETG00000008188(SPSB4),ENSXETG00000012079(SPSB1)" "ENSMUSG00000039911(Spsb1),ENSMUSG00000046997(Spsb4)" "ENSG00000171621(SPSB1),ENSG00000175093(SPSB4)" " embryonic stage | 0-4 hr , adult stage | female " " adult stage && O | stage S6-9 , adult stage " " oocyte

, germarium && nurse cell

, stage S10 oocyte

" "visible,lethal - all die before end of embryonic stage,maternal effect,partially lethal - majority live,viable,fertile,female sterile,some die during embryonic stage" "pole cell,maternal effect,embryo,egg,wing blade,wing margin,ectopic,wing vein,oocyte,oocyte nucleus,stage S8 oocyte,stage S9 oocyte,chorion,dorsal appendage,abdominal ventral denticle belt" DRSC04886 E 1.402502072 -0.681186038 2.250235052 -1.772525788 0.381602547 0.079378174 FBgn0065066 snoRNA:Me28S-A2564 http://flybase.net/reports/FBgn0065066.html FBgn0053778 snoRNA_gene 0030555=RNA modification guide activity 0005730=nucleolus "snoRNA:442, snoR442, CR33778, Me28S-A2564(SnoR442), Dm-442" CR33778 16-Dec-15 2015_12 FBgn0022704 Ca-3 Carbonic anhydrase-3 http://flybase.net/reports/FBgn0022704.html gene CA-3 16-Dec-15 2015_12 FBgn0030683 CG8239 http://flybase.net/reports/FBgn0030683.html protein_coding_gene "0004163=diphosphomevalonate decarboxylase activity, 0005524=ATP binding" "0008299=isoprenoid biosynthetic process, 0019287=isopentenyl diphosphate biosynthetic process, mevalonate pathway" 0005829=cytosol "MVD, MevPPD" "IPR029765=Diphosphomevalonate decarboxylase, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR006204=GHMP kinase N-terminal domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR005935=Diphosphomevalonate/phosphomevalonate decarboxylase, IPR013750=GHMP kinase, C-terminal domain" CG8239 16-Dec-15 2015_12 ENSDARG00000026089(LOC100331425) YNR043W(MVD1) WBGene00012984(Y48B6A.13) ENSXETG00000017427(mvd) ENSMUSG00000006517(Mvd) ENSG00000167508(MVD) "viable,visible" tormogen cell FBgn0039417 CG6073 http://flybase.net/reports/FBgn0039417.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR007205=Protein HGH1 N-terminal, IPR011989=Armadillo-like helical, IPR007206=Protein HGH1 C-terminal" CG6073 16-Dec-15 2015_12 ENSDARG00000035696(brp16) YGR187C(HGH1) WBGene00021900(Y54H5A.2) ENSMUSG00000022554(Brp16) "ENSG00000179801,ENSG00000186979" viable FBgn0083020 snoRNA:ë¬18S-640g snoRNA:ë¬18S-640g http://flybase.net/reports/FBgn0083020.html snoRNA_gene "psi18s-640g, CR34585" CR34585 16-Dec-15 2015_12 FBgn0001511 l(1)10Fe lethal (1) 10Fe http://flybase.net/reports/FBgn0001511.html gene "l(1)L17, 17" 16-Dec-15 2015_12 "lethal,germline clone,recessive,rescuable maternal effect,neurogenic phenotype,partially" FBgn0002803 ms(1)19Fb male sterile (1) 19Fb http://flybase.net/reports/FBgn0002803.html gene ms(1)C 16-Dec-15 2015_12 "male sterile,recessive" FBgn0016854 l(1)N35 lethal (1) N35 http://flybase.net/reports/FBgn0016854.html gene N35 16-Dec-15 2015_12 "lethal,recessive" FBgn0005577 ota5 olfactory trap abnormal 5 http://flybase.net/reports/FBgn0005577.html gene 0007635=chemosensory behavior olfactory-trap-abnormal-5 16-Dec-15 2015_12 "smell perception defective,male" FBgn0060737 l(3)S066905 lethal (3) S066905 http://flybase.net/reports/FBgn0060737.html gene 0669/05 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0016867 l(2)39ADe lethal (2) 39ADe http://flybase.net/reports/FBgn0016867.html gene N6 16-Dec-15 2015_12 lethal FBgn0085492 CG40505 http://flybase.net/reports/FBgn0085492.html FBan0040505 protein_coding_gene 16-Dec-15 2015_12 FBgn0000291 Cg98F-99A Collagen-like 88F-99A http://flybase.net/reports/FBgn0000291.html gene "DCg5, Cg5" 16-Dec-15 2015_12 FBgn0263956 BG01085 http://flybase.net/reports/FBgn0263956.html gene 16-Dec-15 2015_12 "long lived,male limited" FBgn0267496 2SrRNA:CR45836 2S ribosomal RNA:CR45836 http://flybase.net/reports/FBgn0267496.html rRNA_gene CR45836 CR45836 16-Dec-15 2015_12 FBgn0266106 mei-105 meiotic 105 http://flybase.net/reports/FBgn0266106.html gene 0007143=female meiotic division 16-Dec-15 2015_12 "viable,meiotic cell cycle defective,female" FBgn0082995 snoRNA:ë¬28S-1837b snoRNA:ë¬28S-1837b http://flybase.net/reports/FBgn0082995.html snoRNA_gene "Psi28S-1837b, psi28S-1837b, CR34639" CR34639 16-Dec-15 2015_12 FBgn0041243 Gr43a Gustatory receptor 43a http://flybase.net/reports/FBgn0041243.html FBgn0033161 protein_coding_gene "0033041=sweet taste receptor activity, 0008527=taste receptor activity" "0071332=cellular response to fructose stimulus, 0060259=regulation of feeding behavior, 0050909=sensory perception of taste, 0008343=adult feeding behavior, 0050916=sensory perception of sweet taste, 0032098=regulation of appetite" 0016021=integral component of membrane "gr43a, Gustatory receptor 43C.1, CG1712, GR43a, 43C1, Gr43C1, GR43C.1, DmGr43a, 43C.1" IPR013604=7TM chemoreceptor CG1712 16-Dec-15 2015_12 "feeding behavior defective,taste perception defective,viable" prothoracic leg taste bristle chemosensory neuron FBgn0010593 l(2)05287 lethal (2) 05287 http://flybase.net/reports/FBgn0010593.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0044009 Su(rst)B183 Su(rst)B183 http://flybase.net/reports/FBgn0044009.html gene 0001745=compound eye morphogenesis B183 16-Dec-15 2015_12 viable FBgn0033504 CAP CAP http://flybase.net/reports/FBgn0033504.html "FBgn0033503, FBgn0033505" protein_coding_gene 0017166=vinculin binding "0016203=muscle attachment, 0050954=sensory perception of mechanical stimulus, 0007605=sensory perception of sound" 0005925=focal adhesion "Rexin/CAP, CG3451, rexin, CAP/Vinexin, cap, CG18409, Rexin, DCAP, CG18408" "IPR003127=SoHo domain, IPR001452=SH3 domain" CG18408 16-Dec-15 2015_12 "ENSDARG00000003046(sorbs2a),ENSDARG00000061603(si:ch211-51g4.4)" "ENSG00000095637(SORBS1),ENSG00000154556(SORBS2)" "viable,fertile,behavior defective,auditory perception defective,neuroanatomy defective,lethal - all die before end of embryonic stage,partially,some die during embryonic stage" "scolopale cell,Johnston organ,muscle attachment site,muscle attachment site | larval stage" FBgn0260458 PGRP-LD Peptidoglycan recognition protein LD http://flybase.net/reports/FBgn0260458.html "FBgn0035635, FBgn0052912, FBgn0053717, FBtr0077105, FBpp0076811, FBtr0077106, FBpp0076812, FBtr0077107, FBpp0076813, FBtr0077108, FBpp0076814, FBtr0077109, FBpp0076815" protein_coding_gene "0008745=N-acetylmuramoyl-L-alanine amidase activity, 0042834=peptidoglycan binding, 0008270=zinc ion binding" "0009253=peptidoglycan catabolic process, 0006955=immune response" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "Peptidoglycan recognition protein-LD, CG32912, CG5523, CG33717" "IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510=Peptidoglycan recognition protein, IPR002502=N-acetylmuramoyl-L-alanine amidase domain" CG33717 16-Dec-15 2015_12 DRSC10512 I -2.112498321 0.092584615 0.287240874 0.655018972 0.069938496 -0.054833937 FBgn0265510 CR44372 http://flybase.net/reports/FBgn0265510.html non_protein_coding_gene CR44372 16-Dec-15 2015_12 FBgn0020236 ATPCL ATP citrate lyase http://flybase.net/reports/FBgn0020236.html "FBgn0010490, FBgn0044698" protein_coding_gene "0005524=ATP binding, 0003878=ATP citrate synthase activity, 0048037=cofactor binding" "0006101=citrate metabolic process, 0006085=acetyl-CoA biosynthetic process, 0044262=cellular carbohydrate metabolic process" "0005737=cytoplasm, 0005811=lipid particle" "dATPCL, BcDNA:LD21334, ATP-citrate lyase, anon-WO0140519.179, DmATPCL, l(2)01466, l(2)k09217, ATP citrate lyase, n(2)k09217, CG8322, ACL" "IPR003781=CoA-binding, IPR016102=Succinyl-CoA synthetase-like, IPR005810=Succinyl-CoA ligase, alpha subunit, IPR028097=FAM91, C-terminal domain, IPR017440=ATP-citrate lyase/succinyl-CoA ligase, active site, IPR016143=Citrate synthase-like, small alpha subdomain, IPR013816=ATP-grasp fold, subdomain 2, IPR017866=Succinyl-CoA synthetase, beta subunit, conserved site, IPR014608=ATP-citrate synthase, IPR028091=FAM91, N-terminal domain, IPR002020=Citrate synthase, IPR013650=ATP-grasp fold, succinyl-CoA synthetase-type, IPR005811=ATP-citrate lyase/succinyl-CoA ligase, IPR016040=NAD(P)-binding domain, IPR016142=Citrate synthase-like, large alpha subdomain" CG8322 16-Dec-15 2015_12 "ENSDARG00000055652,ENSDARG00000017738(aclya)" "WBGene00007150(B0365.1),WBGene00016995(D1005.1)" ENSXETG00000002292(ACLY) ENSMUSG00000020917(Acly) ENSG00000131473(ACLY) "viable,lethal,recessive,partially lethal - majority die,visible,some die during pupal stage" "trichogen cell,supernumerary,mesothoracic tergum" FBgn0051663 CG31663 http://flybase.net/reports/FBgn0051663.html "FBgn0031370, FBgn0040720, FBgn0063216" protein_coding_gene "BcDNA:GH27779, CG15360, CG15359" "IPR020846=Major facilitator superfamily domain, IPR024989=Major facilitator superfamily associated domain" CG31663 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0011472 l(3)neo39 lethal (3) neo39 http://flybase.net/reports/FBgn0011472.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0039335 Vps33B Vacuolar protein sorting 33B http://flybase.net/reports/FBgn0039335.html protein_coding_gene "0019905=syntaxin binding, 0005515=protein binding" "0006955=immune response, 0006904=vesicle docking involved in exocytosis, 0035542=regulation of SNARE complex assembly, 0016192=vesicle-mediated transport, 0016197=endosomal transport, 0090307=mitotic spindle assembly, 0007476=imaginal disc-derived wing morphogenesis" "0030897=HOPS complex, 0033263=CORVET complex" "Vps33b, dVps33B, Vps 33B, VPS33b, CG5127" "IPR027482=Sec1-like, domain 2, IPR001619=Sec1-like protein, IPR027121=Vacuolar protein sorting-associated protein 33" CG5127 16-Dec-15 2015_12 "viable,immune response defective" FBgn0004029 ww wider wing http://flybase.net/reports/FBgn0004029.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,female,reduced,female fertile,male fertile" wing FBgn0010101 amiel amiel http://flybase.net/reports/FBgn0010101.html gene Amiel 16-Dec-15 2015_12 "courtship behavior defective,male,recessive,mating defective" FBgn0003664 Thar Thickened arista http://flybase.net/reports/FBgn0003664.html gene Ta 16-Dec-15 2015_12 "visible,semidominant,lethal,recessive" arista FBgn0030508 CG15760 http://flybase.net/reports/FBgn0030508.html protein_coding_gene IPR021684=Uncharacterised protein family WW domain-binding protein 1 CG15760 16-Dec-15 2015_12 viable FBgn0263993 CG43736 http://flybase.net/reports/FBgn0263993.html "FBgn0064122, FBgn0029916, FBgn0029917, FBgn0052737, FBgn0053691, FBtr0070996, FBpp0070956, FBtr0070997, FBtr0070998, FBpp0070958, FBtr0070999, FBgn0064121, FBgn0029918, FBgn0053692, FBpp0070957, FBpp0070959" protein_coding_gene 0007476=imaginal disc-derived wing morphogenesis "CG14433, CG32737 ORF A, CG4564, CG33692, CG32737-ORFB, CG32737, CG33691, CG32737-ORFA, CG4571" CG43736 16-Dec-15 2015_12 FBgn0060558 l(3)S097301b lethal (3) S097301b http://flybase.net/reports/FBgn0060558.html gene "l(3)097301, 0973/01" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0262301 mir-979 mir-979 stem loop http://flybase.net/reports/FBgn0262301.html miRNA_gene "CR43008, dme-mir-979, miR-979" CR43008 16-Dec-15 2015_12 viable FBgn0039041 CG13838 http://flybase.net/reports/FBgn0039041.html protein_coding_gene IPR022788=Uncharacterised protein family UPF0184 CG13838 16-Dec-15 2015_12 FBgn0042687 Tirant\env env http://flybase.net/reports/FBgn0042687.html transposable_element_gene "ORF3, env" IPR009882=Gypsy 16-Dec-15 2015_12 FBgn0067871 Mod(Prat:bw)3-4 Mod(Prat:bw)3-4 http://flybase.net/reports/FBgn0067871.html gene Mod-3-4 16-Dec-15 2015_12 enhancer of variegation FBgn0035194 Psf1 Psf1 http://flybase.net/reports/FBgn0035194.html protein_coding_gene 0043138=3'-5' DNA helicase activity "0022008=neurogenesis, 0046331=lateral inhibition, 1900087=positive regulation of G1/S transition of mitotic cell cycle" 0000811=GINS complex "CG9187-PA, CG9187, psf1" "IPR005339=GINS complex, subunit Psf1" CG9187 16-Dec-15 2015_12 "ENSDARG00000068633,ENSDARG00000007624" YDR013W(PSF1) WBGene00011275(R53.6) ENSXETG00000027032(GINS1) ENSMUSG00000027454(Gins1) ENSG00000101003(GINS1) "lethal,neuroanatomy defective,viable,visible" "rhabdomere R7,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0013644 mfs(2)ry10 mfs(2)ry10 http://flybase.net/reports/FBgn0013644.html gene "unnamed, mfs(2)10" 16-Dec-15 2015_12 "male sterile,female sterile" FBgn0062519 substance-P substance P http://flybase.net/reports/FBgn0062519.html gene 0005184=neuropeptide hormone activity SP 16-Dec-15 2015_12 FBgn0038130 CG8630 http://flybase.net/reports/FBgn0038130.html protein_coding_gene 0004768=stearoyl-CoA 9-desaturase activity "0006629=lipid metabolic process, 0055114=oxidation-reduction process" "IPR005804=Fatty acid desaturase domain, IPR015876=Fatty acid desaturase, type 1, core" CG8630 16-Dec-15 2015_12 YGL055W(OLE1) "WBGene00001398(fat-6),WBGene00001399(fat-7),WBGene00001397(fat-5)" lethal DRSC16441 EK 1.150896546 0.343532663 2.859822058 -0.968624992 -0.567219876 -1.568681694 FBgn0029529 CG13365 http://flybase.net/reports/FBgn0029529.html FBgn0063102 protein_coding_gene BcDNA:LP07417 CG13365 16-Dec-15 2015_12 viable FBgn0265854 CR44643 http://flybase.net/reports/FBgn0265854.html non_protein_coding_gene CR44643 16-Dec-15 2015_12 FBgn0016648 En(en)eg-1 En(en)eg-1 http://flybase.net/reports/FBgn0016648.html gene 16-Dec-15 2015_12 "wing vein,trichome of the posterior wing margin" FBgn0266221 CR44916 http://flybase.net/reports/FBgn0266221.html non_protein_coding_gene CR44916 16-Dec-15 2015_12 FBgn0264824 CR44032 http://flybase.net/reports/FBgn0264824.html non_protein_coding_gene CG44032 CR44032 16-Dec-15 2015_12 FBgn0031538 CG3246 http://flybase.net/reports/FBgn0031538.html protein_coding_gene 0008289=lipid binding "IPR017943=Bactericidal permeability-increasing protein, alpha/beta domain, IPR010562=Haemolymph juvenile hormone binding" CG3246 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0060616 l(3)S089707b lethal (3) S089707b http://flybase.net/reports/FBgn0060616.html gene 0897/07 16-Dec-15 2015_12 "lethal,recessive" FBgn0053459 CG33459 http://flybase.net/reports/FBgn0053459.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "HDC06756, unnamed" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG33459 16-Dec-15 2015_12 WBGene00006621(try-3) "lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0260783 9-220 http://flybase.net/reports/FBgn0260783.html gene 16-Dec-15 2015_12 chemical sensitive FBgn0025816 MBP1 MBT-binding protein 1 http://flybase.net/reports/FBgn0025816.html gene 16-Dec-15 2015_12 FBgn0052183 Ccn Ccn http://flybase.net/reports/FBgn0052183.html "FBgn0036748, FBgn0040792" protein_coding_gene 0008083=growth factor activity 0022008=neurogenesis "CG13735, CG13736, dCCN, CG32183" "IPR001007=VWFC domain, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR006207=Cystine knot, C-terminal" CG32183 16-Dec-15 2015_12 "ENSDARG00000006823(cyr61),ENSDARG00000035422(cyr61l1),ENSDARG00000023062(zgc:85866),ENSDARG00000027360(si:ch211-106h11.3),ENSDARG00000070586(si:ch211-173b8.2),ENSDARG00000042934(ctgf),ENSDARG00000054331(wisp1a),ENSDARG00000037138,ENSDARG00000071048(wisp3)" "ENSXETG00000003094(Q5BL74_XENTR),ENSXETG00000008245(CTGF),ENSXETG00000003135(NOV),ENSXETG00000010987(WISP1),ENSXETG00000023462(),ENSXETG00000027362(BC087808.1)" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval neuroblast FBgn0259677 CG42346 http://flybase.net/reports/FBgn0259677.html "FBan0040500, FBgn0069968, FBgn0069939, FBan0041105" protein_coding_gene "CG40500, CG40500-PA, CG41105" "IPR001611=Leucine-rich repeat, IPR026906=Leucine rich repeat 5, IPR013783=Immunoglobulin-like fold, IPR003961=Fibronectin type III, IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal" CG42346 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell FBgn0261086 Syt14 Synaptotagmin 14 http://flybase.net/reports/FBgn0261086.html "FBgn0084789, FBgn0037233, FBan0009778" protein_coding_gene 0005544=calcium-dependent phospholipid binding "0048812=neuron projection morphogenesis, 0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport" 0016021=integral component of membrane "Syt16, CG9778, syt14, Syt 14, synaptotagmin 14, syt16, dsyt14" IPR000008=C2 domain CG9778 16-Dec-15 2015_12 "ENSDARG00000030761,ENSDARG00000010934,ENSDARG00000001891" ENSXETG00000000217(SYT14) "ENSMUSG00000016200(Syt14),ENSMUSG00000044912(Syt16)" "ENSG00000143469(SYT14),ENSG00000139973(SYT16)" FBgn0067321 C45 C45 http://flybase.net/reports/FBgn0067321.html gene 16-Dec-15 2015_12 "visible,lethal,viable" chaeta FBgn0043883 mdg1\ORF ORF http://flybase.net/reports/FBgn0043883.html transposable_element_gene 0003676=nucleic acid binding 0015074=DNA integration "IPR001584=Integrase, catalytic core, IPR012337=Ribonuclease H-like domain" 16-Dec-15 2015_12 FBgn0021775 mmei-1 mmei-1 http://flybase.net/reports/FBgn0021775.html gene 0007140=male meiosis m1 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" "spermatocyte,primary spermatocyte cyst,onion stage spermatid,spermatozoon" FBgn0261594 M(3)93A Minute (3) 93A http://flybase.net/reports/FBgn0261594.html gene 16-Dec-15 2015_12 FBgn0265721 CR44528 http://flybase.net/reports/FBgn0265721.html non_protein_coding_gene "lincRNA.435, incRNA.435" CR44528 16-Dec-15 2015_12 FBgn0060930 l(3)S042008 lethal (3) S042008 http://flybase.net/reports/FBgn0060930.html gene 0420/08 16-Dec-15 2015_12 "lethal,recessive" FBgn0086442 mib2 mind bomb 2 http://flybase.net/reports/FBgn0086442.html "FBgn0032742, FBgn0002024" protein_coding_gene "0008270=zinc ion binding, 0032038=myosin II heavy chain binding, 0004842=ubiquitin-protein transferase activity, 0032033=myosin II light chain binding" "0046716=muscle cell cellular homeostasis, 0000209=protein polyubiquitination, 0007520=myoblast fusion" "0031430=M band, 0030018=Z disc, 0005737=cytoplasm" "lethal (2) 37Be, i115, Be, mindbomb2, l(2)37Be, suelto, mib1/2, mind bomb 2, D-mibl, Mind bomb 2, CG17492, Mib-2" "IPR001841=Zinc finger, RING-type, IPR000433=Zinc finger, ZZ-type, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR010606=Mib-herc2" CG17492 16-Dec-15 2015_12 ENSDARG00000008424 WBGene00012933(Y47D3A.22) ENSXETG00000019608(MIB2) ENSMUSG00000029060(Mib2) ENSG00000197530(MIB2) FBgn0051098 CG31098 http://flybase.net/reports/FBgn0051098.html "FBgn0039317, FBgn0064903, FBgn0064951" protein_coding_gene "BcDNA:RE13429, BcDNA:GH27183, CG10634" "IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like" CG31098 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0013247 E(var)3-12 E(var)3-12 http://flybase.net/reports/FBgn0013247.html gene E-var(3)12 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0039510 CG3339 http://flybase.net/reports/FBgn0039510.html protein_coding_gene "0016887=ATPase activity, 0003777=microtubule motor activity, 0042623=ATPase activity, coupled, 0003774=motor activity, 0005524=ATP binding" 0007018=microtubule-based movement "0005868=cytoplasmic dynein complex, 0005875=microtubule associated complex, 0030286=dynein complex" "IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013594=Dynein heavy chain, domain-1, IPR004273=Dynein heavy chain domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR011704=ATPase, dynein-related, AAA domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR026983=Dynein heavy chain" CG3339 16-Dec-15 2015_12 viable DRSC13821 E -0.064717041 -0.092012619 1.69188237 1.00368574 0.509122396 -0.379680867 FBgn0265138 Gr22c Gustatory receptor 22c http://flybase.net/reports/FBgn0265138.html "FBgn0045499, FBgn0045492, FBgn0051929, FBgn0041214" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "Gustatory receptor 2940.3, GR22c, GRLU.6, CG31929, Gustatory receptor LU.6, LU.6, Gr2940.3, GrLU6" IPR013604=7TM chemoreceptor CG31929 16-Dec-15 2015_12 FBgn0020341 anon-5Ca anon-5Ca http://flybase.net/reports/FBgn0020341.html gene unnamed 16-Dec-15 2015_12 FBgn0065415 l(2)SH1550 lethal (2) SH1550 http://flybase.net/reports/FBgn0065415.html gene l(2)SH2 1550 16-Dec-15 2015_12 "lethal,recessive" FBgn0265831 CR44620 http://flybase.net/reports/FBgn0265831.html non_protein_coding_gene lincRNA.986 CR44620 16-Dec-15 2015_12 FBgn0051083 CG31083 http://flybase.net/reports/FBgn0051083.html FBgn0064839 protein_coding_gene BcDNA:RH14203 16-Dec-15 2015_12 FBgn0033827 CG17047 http://flybase.net/reports/FBgn0033827.html protein_coding_gene IPR000859=CUB domain CG17047 16-Dec-15 2015_12 viable FBgn0035300 CG1139 http://flybase.net/reports/FBgn0035300.html protein_coding_gene 0015171=amino acid transmembrane transporter activity "0040007=growth, 0003333=amino acid transmembrane transport" "IPR013057=Amino acid transporter, transmembrane domain" CG1139 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "WBGene00012804(Y43F4B.7),WBGene00020837(T27A1.5)" "increased cell number,decreased cell number,increased cell size,viable" "ommatidium,eye,wing" FBgn0264748 CG44006 http://flybase.net/reports/FBgn0264748.html protein_coding_gene CG34252 CG44006 16-Dec-15 2015_12 FBgn0020399 Mst89B Mst89B http://flybase.net/reports/FBgn0020399.html protein_coding_gene 0007283=spermatogenesis 0005737=cytoplasm CG6864 CG6864 16-Dec-15 2015_12 " larval stage | third instar , spermatogenesis && adult stage , pupal stage , adult stage " testis

viable FBgn0053200 VepD Ventrally-expressed protein D http://flybase.net/reports/FBgn0053200.html "FBgn0019857, FBgn0041089" protein_coding_gene 0007275=multicellular organismal development "vepD, ventrally-expressed-protein-D, anon-EST:CL57, ventrally expressed protein-D, CG33200, D" CG33200 16-Dec-15 2015_12 " embryonic stage | stage >5 , embryonic stage | stage 5 " " mesoderm

, mesoderm anlage | segmentally repeated

" FBgn0085506 CG40635 http://flybase.net/reports/FBgn0085506.html FBan0040635 protein_coding_gene 0019887=protein kinase regulator activity 0005956=protein kinase CK2 complex "IPR000704=Casein kinase II, regulatory subunit, IPR016149=Casein kinase II, regulatory subunit, alpha-helical" CG40635 16-Dec-15 2015_12 FBgn0052518 tRNA:CR32518:ë¬ transfer RNA:CR32518:pseudogene http://flybase.net/reports/FBgn0052518.html FBgn0060203 pseudogene_attribute "chrX.trna19-IleAAT, CR32518, AE002620.trna2-IleAAT, tRNA:IPsi:AAT:AE002620" CR32518 16-Dec-15 2015_12 FBgn0259618 B1516 http://flybase.net/reports/FBgn0259618.html gene 16-Dec-15 2015_12 lethal FBgn0085253 CG34224 http://flybase.net/reports/FBgn0085253.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006355=regulation of transcription, DNA-templated" "IPR001289=CCAAT-binding transcription factor, subunit B" CG34224 16-Dec-15 2015_12 FBgn0000829 fs(1)M8 female sterile (1) M8 http://flybase.net/reports/FBgn0000829.html gene 16-Dec-15 2015_12 "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0030828 CG5162 http://flybase.net/reports/FBgn0030828.html protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" "0016042=lipid catabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG5162 16-Dec-15 2015_12 viable DRSC19935 K 0.34369369 -0.902714744 -1.295961033 0.219595043 1.569173165 -0.17514515 FBgn0060337 l(3)S144606 lethal (3) S144606 http://flybase.net/reports/FBgn0060337.html gene 1446/06 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0000709 fliI flightless I http://flybase.net/reports/FBgn0000709.html FBgn0001732 protein_coding_gene "0003779=actin binding, 0005509=calcium ion binding" "0010004=gastrulation involving germ band extension, 0051014=actin filament severing, 0007527=adult somatic muscle development, 0030239=myofibril assembly, 0007629=flight behavior" "Fli-I, fli-I, W2, 15, DCA3-19, FLI-I, l(1)18-80, lgluful-2, l(1)W-2, CT3691, l(1)19Fd, unnamed, sdby, fltO, flightless, gluful-2, Flightless-I, CG1484, l(1)ESHS53, BcDNA:LD21753, standby, w-2, EN3, lDCB2-19, fli I, section 15, fli, fltI" "IPR003591=Leucine-rich repeat, typical subtype, IPR029919=Protein flightless-1, IPR029006=ADF-H/Gelsolin-like domain, IPR001611=Leucine-rich repeat, IPR007123=Gelsolin-like domain, IPR007122=Villin/Gelsolin" CG1484 16-Dec-15 2015_12 ENSDARG00000059701(flii) WBGene00001443(fli-1) ENSXETG00000005767(flii) ENSMUSG00000002812(Flii) ENSG00000177731(FLII) embryonic stage -- adult stage "lethal,recessive,flightless,heat sensitive,flight defective,germline clone,maternal effect,non-rescuable maternal effect,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,partially lethal - majority die" "indirect flight muscle,myofibril,Z disc,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,striated muscle thin filament,embryonic abdominal segment & epidermis | germ-line clone,embryo,maternal effect,embryonic epidermis,mesoderm,gastrula embryo,germline clone,non-rescuable maternal effect,blastoderm embryo,sarcomere,striated muscle myosin thick filament,muscle cell,myofibrilMef2.PR" DRSC20578 I -0.14884126 2.114245027 -0.21130229 -0.142839063 0.841405066 -0.024045431 FBgn0259534 GG01365 http://flybase.net/reports/FBgn0259534.html gene 16-Dec-15 2015_12 visible "wing,proximal,tarsal segment,wing vein,chaeta,ectopic" FBgn0036448 mop myopic http://flybase.net/reports/FBgn0036448.html protein_coding_gene 0004725=protein tyrosine phosphatase activity "0006470=protein dephosphorylation, 0002775=antimicrobial peptide production, 0045752=positive regulation of Toll signaling pathway, 0051225=spindle assembly, 0040008=regulation of growth, 0045742=positive regulation of epidermal growth factor receptor signaling pathway" "0005768=endosome, 0031982=vesicle" "myopic, mop, slaughterhouse-five, sfv, CG9311" "IPR000242=PTP type protein phosphatase, IPR004328=BRO1 domain, IPR025304=ALIX V-shaped domain, IPR029021=Protein-tyrosine phosphatase-like" CG9311 16-Dec-15 2015_12 "ENSDARG00000070124(ptp23a),ENSDARG00000070870(si:dkeyp-114f9.2)" WBGene00001215(ego-2) ENSXETG00000020359(PTPN23) ENSMUSG00000036057(Ptpn23) ENSG00000076201(PTPN23) "lethal,recessive,size defective,somatic clone,visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell number" "eye,somatic clone,wing vein,eye photoreceptor cell,eye disc,inter-ommatidial cell,supernumerary" FBgn0011985 tRNA:S7:23Eb transfer RNA:ser7:23Eb http://flybase.net/reports/FBgn0011985.html "FBgn0003831, FBgn0011968, FBgn0011979, FBgn0051734, FBgn0060064" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033405=UCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:S:AGA:AE002638-b, tRNA:ser, 777-4, tRNA[Ser], transfer RNA:ser, chr2L.trna7-SerAGA, AE002638.trna14-SerAGA, tRNA[[Ser]], tRNA:S, CR31734, transfer RNA:ser7, tRNA:ser7:23Eb, tRNA:ser7, tRNA[Ser][[7]], tRNA:S7, tRNA[[7]][Ser]" CR31734 16-Dec-15 2015_12 FBgn0051166 tRNA:CR31166 transfer RNA:CR31166 http://flybase.net/reports/FBgn0051166.html "FBgn0011968, FBgn0011969, FBgn0011972, FBgn0060058" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033446=AGC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:ser, transfer RNA:ser2b:94A, tRNA:S:GCT:AE002708-b, tRNA:S2b, tRNA[[Ser]], transfer RNA:ser2b, tRNA:S2b:94A, CR31166, tRNA[Ser][[2b]], chr3R.trna33-SerGCT, transfer RNA:ser, tRNA:ser2b, tRNA:S, tRNA:ser2b:94A, AE002708.trna27-SerGCT" CR31166 16-Dec-15 2015_12 FBgn0000402 cxb calyx bulging http://flybase.net/reports/FBgn0000402.html gene 16-Dec-15 2015_12 "female sterile,behavior defective" "ellipsoid body,nodulus,lobe system of adult mushroom body,calyx of adult mushroom body" FBgn0051631 tRNA:CR31631 transfer RNA:CR31631 http://flybase.net/reports/FBgn0051631.html FBgn0060087 tRNA_gene 0033448=AGG codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002690.trna1-ArgCCT, tRNA:R:CCT:AE002690, CR31631, chr2L.trna9-ArgCCT" CR31631 16-Dec-15 2015_12 FBgn0029027 l(3)77ABd lethal (3) 77ABd http://flybase.net/reports/FBgn0029027.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001306 Kg Kugel http://flybase.net/reports/FBgn0001306.html gene "Ch, Ch[V], Chubby, Chubby of Valencia" 16-Dec-15 2015_12 "viable,fertile,visible,reduced" "larva,pupa,adult" FBgn0001723 l(1)ESHS44 lethal (1) ESHS44 http://flybase.net/reports/FBgn0001723.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265742 CR44549 http://flybase.net/reports/FBgn0265742.html non_protein_coding_gene CR44549 16-Dec-15 2015_12 FBgn0266930 CR45381 http://flybase.net/reports/FBgn0266930.html non_protein_coding_gene CR45381 16-Dec-15 2015_12 FBgn0034988 cN-IIIB cytosolic 5'-nucleotidase IIIB http://flybase.net/reports/FBgn0034988.html protein_coding_gene "0008252=nucleotidase activity, 0000287=magnesium ion binding, 0008253=5'-nucleotidase activity" "1901069=guanosine-containing compound catabolic process, 0009158=ribonucleoside monophosphate catabolic process" 0005829=cytosol "cNIII-like, cytosolic nucleotidase III-like, 16769374, CG3362" "IPR023214=HAD-like domain, IPR006434=Pyrimidine 5'-nucleotidase, eukaryotic" CG3362 16-Dec-15 2015_12 "WBGene00012423(Y10G11A.1),WBGene00017775(F25B5.3)" "ENSXETG00000021122(NT5C3),ENSXETG00000002290()" "ENSMUSG00000017176(Nt5c3l),ENSMUSG00000029780(Nt5c3)" "ENSG00000141698(NT5C3L),ENSG00000122643(NT5C3)" "viable,fertile" FBgn0036696 CG14057 http://flybase.net/reports/FBgn0036696.html protein_coding_gene 0004526=ribonuclease P activity "0046331=lateral inhibition, 0022008=neurogenesis, 0008033=tRNA processing, 0009267=cellular response to starvation" 0005634=nucleus "IPR016819=Ribonuclease P/MRP protein subunit Pop5, IPR002759=Ribonuclease P/MRP protein subunit" CG14057 16-Dec-15 2015_12 ENSDARG00000053452(pop5) YAL033W(POP5) WBGene00013422(Y66A7A.2) ENSMUSG00000060152(Pop5) ENSG00000167272(POP5) "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,chaeta" FBgn0060321 l(3)S146912 lethal (3) S146912 http://flybase.net/reports/FBgn0060321.html gene 1469/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0025679 Bteb2 Bteb2 http://flybase.net/reports/FBgn0025679.html protein_coding_gene "0046872=metal ion binding, 0043565=sequence-specific DNA binding" 0045944=positive regulation of transcription from RNA polymerase II promoter 0005634=nucleus "BteB2, BTEB2, CG2932" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG2932 16-Dec-15 2015_12 "ENSDARG00000067727,ENSDARG00000062510" YMR037C(MSN2) ENSG00000119138(KLF9) "viable,fertile" FBgn0067069 N12 N12 http://flybase.net/reports/FBgn0067069.html gene 16-Dec-15 2015_12 "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0044119 E(rst)B92 E(rst)B92 http://flybase.net/reports/FBgn0044119.html gene 0001745=compound eye morphogenesis B92 16-Dec-15 2015_12 FBgn0039639 CG14512 http://flybase.net/reports/FBgn0039639.html protein_coding_gene "0016758=transferase activity, transferring hexosyl groups, 0030246=carbohydrate binding" 0030259=lipid glycosylation "dAlg13, Alg13" "IPR007235=Glycosyl transferase, family 28, C-terminal" CG14512 16-Dec-15 2015_12 ENSDARG00000011026(zgc:92907) YGL047W(ALG13) WBGene00011193(R10D12.12) ENSXETG00000023418() "ENSMUSG00000031286(Glt28d2),ENSMUSG00000079411(Alg13)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC14864 IE -2.520487323 0.397045261 1.578561822 0.708834874 0.474462802 -0.116763955 FBgn0262974 CR43285 http://flybase.net/reports/FBgn0262974.html non_protein_coding_gene CG43285 CR43285 16-Dec-15 2015_12 FBgn0023160 Su(mg)1-8 Suppressor of modifier of gypsy 1-8 http://flybase.net/reports/FBgn0023160.html gene 16-Dec-15 2015_12 FBgn0060422 l(3)S127816 lethal (3) S127816 http://flybase.net/reports/FBgn0060422.html gene 1278/16 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0052766 CR32766 http://flybase.net/reports/FBgn0052766.html non_protein_coding_gene 16-Dec-15 2015_12 FBgn0050156 CG30156 http://flybase.net/reports/FBgn0050156.html "FBgn0045831, FBgn0065028" protein_coding_gene 0022008=neurogenesis "BcDNA:AT02529, BEST:GH05253" "IPR015399=Domain of unknown function DUF1977, DnaJ-like, IPR001623=DnaJ domain" CG30156 16-Dec-15 2015_12 YMR161W(HLJ1) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0028115 l(3)S064301 lethal (3) S064301 http://flybase.net/reports/FBgn0028115.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265555 12.82 http://flybase.net/reports/FBgn0265555.html gene 16-Dec-15 2015_12 learning defective FBgn0062518 752 752 http://flybase.net/reports/FBgn0062518.html gene 0007179=transforming growth factor beta receptor signaling pathway #752 16-Dec-15 2015_12 FBgn0022377 Pt-13 Larval protein-13 http://flybase.net/reports/FBgn0022377.html gene 16-Dec-15 2015_12 FBgn0031900 CG13786 http://flybase.net/reports/FBgn0031900.html protein_coding_gene CG13786 16-Dec-15 2015_12 viable DRSC02289 I 0.427471052 2.009075973 0.751574122 -1.433574657 0.464278943 -0.241209096 FBgn0038476 kuk kugelkern http://flybase.net/reports/FBgn0038476.html protein_coding_gene "0008344=adult locomotory behavior, 0006997=nucleus organization, 0007569=cell aging, 0016331=morphogenesis of embryonic epithelium, 0007349=cellularization" "0005811=lipid particle, 0005637=nuclear inner membrane" "char, Kugelkern, Kugelkem, Kugelkern/Charleston, charleston, kuk/char, Kuk, CG5175" CG5175 16-Dec-15 2015_12 "viable,fertile,short lived,gravitaxis defective,partially lethal - majority die" "nucleus | embryonic stage,nuclear envelope | embryonic stage 5P5), with Df(3R)C4,nucleus | embryonic stage 5P5), with Df(3R)C4,stage 6 embryo,epithelial cell,cell-cell junctionP5), with Df(3R)C4,longitudinal muscle,nucleus | adult stageMhc.Switch.PO,brain,nucleus | adult stageelav.Switch.PO,nucleus | adult stage,embryo,nucleus | embryonic stage 9,nucleus | gastrula stage,nucleus | blastoderm stage" FBgn0014328 l(3)ry73 lethal (3) ry73 http://flybase.net/reports/FBgn0014328.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050017 CG30017 http://flybase.net/reports/FBgn0050017.html "FBgn0045926, FBgn0045933, FBgn0047236" protein_coding_gene "BcDNA:HL05382, anon-WO0153538.29, anon-WO0153538.22" 16-Dec-15 2015_12 viable FBgn0260067 2L1663 http://flybase.net/reports/FBgn0260067.html gene 16-Dec-15 2015_12 "lethal,viable" "embryonic/larval tracheal system,somatic clone" FBgn0010081 Rst(3)mth2 Resistance (3) malathion 2 http://flybase.net/reports/FBgn0010081.html gene 16-Dec-15 2015_12 FBgn0069969 CG40498 http://flybase.net/reports/FBgn0069969.html FBan0040498 protein_coding_gene CG40498 16-Dec-15 2015_12 FBgn0259739 CG42393 http://flybase.net/reports/FBgn0259739.html protein_coding_gene CG42393 16-Dec-15 2015_12 FBgn0267452 CR45802 http://flybase.net/reports/FBgn0267452.html non_protein_coding_gene CR45802 16-Dec-15 2015_12 FBgn0260867 CG42577 http://flybase.net/reports/FBgn0260867.html protein_coding_gene CG42577 16-Dec-15 2015_12 FBgn0085188 CG34159 http://flybase.net/reports/FBgn0085188.html protein_coding_gene CG5739 IPR029428=FAM195 CG34159 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067063 O18 O18 http://flybase.net/reports/FBgn0067063.html gene 16-Dec-15 2015_12 "eye color defective,lethal,partially lethal - majority die" pigment cell FBgn0015035 Cyp4e3 Cytochrome P450-4e3 http://flybase.net/reports/FBgn0015035.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane, 0005811=lipid particle" "4e3, cytochrome P450, cyp4e3, Cytochrome P450, Cyp4E3, P450, P-450, CG4105" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG4105 16-Dec-15 2015_12 YMR015C(ERG5) "partially lethal - majority die,some die during pupal stage" DRSC03306 K 0.076295432 0.387234698 0.031325567 -0.111789663 2.446970416 1.177269737 FBgn0083068 CG33947 putative noncoding RNA 011:3L http://flybase.net/reports/FBgn0083068.html "FBgn0046307, FBgn0053947, FBgn0063280" protein_coding_gene 0005829=cytosol "BEST:GH03576, CR33947, BcDNA:GH03576, pncr011:3L, GH03576" CG33947 16-Dec-15 2015_12 FBgn0028606 l(2)W19 lethal (2) W19 http://flybase.net/reports/FBgn0028606.html gene l(2R)W19 16-Dec-15 2015_12 "lethal,recessive" FBgn0266488 CG45087 http://flybase.net/reports/FBgn0266488.html protein_coding_gene Dromel_CG17725_FBtr0086701_pepck_uORF CG45087 16-Dec-15 2015_12 FBgn0037573 eIF4AIII eIF4AIII http://flybase.net/reports/FBgn0037573.html "FBgn0004221, FBgn0062067" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0003743=translation initiation factor activity" "0045451=pole plasm oskar mRNA localization, 0070374=positive regulation of ERK1 and ERK2 cascade, 0006413=translational initiation, 0008380=RNA splicing, 0046579=positive regulation of Ras protein signal transduction, 1903040=exon-exon junction complex assembly, 0000398=mRNA splicing, via spliceosome, 0006974=cellular response to DNA damage stimulus" "0045495=pole plasm, 0071011=precatalytic spliceosome, 0005634=nucleus, 0071013=catalytic step 2 spliceosome, 0016281=eukaryotic translation initiation factor 4F complex" "eIF4A, 7483, eIF4A-III, eIF4A3, eukaryotic translation initiation factor 4AIII, DmRH28, anon-WO0118547.364, l(3)84Fi, EIF4AIII, lethal(3)84Fi, CG7483" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain" CG7483 16-Dec-15 2015_12 ENSDARG00000014472(LOC100330671) YDR021W(FAL1) "WBGene00018007(F33D11.10),WBGene00022029(Y65B4A.6)" ENSXETG00000013720(ddx48) "ENSMUSG00000025580(Eif4a3),ENSMUSG00000060782" ENSG00000141543(EIF4A3) "lethal,germline clone,increased cell death" "cytoskeleton & oocyte | germ-line clone,nucleus & oocyte | germ-line clone,oocyte associated follicle cell,germline clone" DRSC26402 EK -0.76018031 -0.259375491 -0.782895709 -2.002493802 -2.276678911 -3.853109736 FBgn0259709 CG42363 http://flybase.net/reports/FBgn0259709.html "FBgn0034648, FBan0015675" protein_coding_gene CG15675 CG42363 16-Dec-15 2015_12 FBgn0032123 Oatp30B Organic anion transporting polypeptide 30B http://flybase.net/reports/FBgn0032123.html protein_coding_gene "0008514=organic anion transmembrane transporter activity, 0005215=transporter activity" 0015711=organic anion transport 0016021=integral component of membrane "CG3811, oatp 30B, oatp30B" "IPR002350=Kazal domain, IPR004156=Organic anion transporter polypeptide OATP, IPR020846=Major facilitator superfamily domain" CG3811 16-Dec-15 2015_12 ENSDARG00000071685(LOC556735) ENSXETG00000015232(SLCO5A1) ENSMUSG00000025938(Slco5a1) ENSG00000137571(SLCO5A1) "viable,fertile,visible,planar polarity defective" trichogen cell FBgn0019960 Mitofilin Mitofilin http://flybase.net/reports/FBgn0019960.html protein_coding_gene "0070584=mitochondrion morphogenesis, 0022008=neurogenesis" "0005739=mitochondrion, 0005743=mitochondrial inner membrane" "Motor-protein, CG6455, dmitofilin, Motor protein, CG 6455" IPR019133=Mitochondrial inner membrane protein Mitofilin CG6455 16-Dec-15 2015_12 ENSDARG00000057454(immt) "WBGene00020511(immt-1),WBGene00012315(immt-2)" ENSMUSG00000052337(Immt) ENSG00000132305(IMMT) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0028538 Sec71 Sec71 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0028538.html FBgn0027855 protein_coding_gene "0005515=protein binding, 0005086=ARF guanyl-nucleotide exchange factor activity" "0006888=ER to Golgi vesicle-mediated transport, 0006891=intra-Golgi vesicle-mediated transport, 0016192=vesicle-mediated transport, 0032012=regulation of ARF protein signal transduction" "0005794=Golgi apparatus, 0005802=trans-Golgi network" "BG:DS00797.7, Sec71, BIG1, CG7578, sec71" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR023394=Sec7 domain, alpha orthogonal bundle, IPR015403=Domain of unknown function DUF1981, Sec7 associated, IPR000904=Sec7 domain" CG7578 16-Dec-15 2015_12 ENSDARG00000063474 YDR170C(SEC7) WBGene00012386(agef-1) ENSXETG00000001785(ARFGEF2) "ENSMUSG00000074582(Arfgef2),ENSMUSG00000067851(Arfgef1)" "ENSG00000066777(ARFGEF1),ENSG00000124198(ARFGEF2)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC01893 I 1.728272202 0.876243531 1.280913621 -0.6216505 0.831588109 0.510418398 FBgn0004929 A-p Abnormal abdomen polygenic http://flybase.net/reports/FBgn0004929.html gene "Asy, Asymmetric, AA" 16-Dec-15 2015_12 FBgn0069214 gsu goldstaub http://flybase.net/reports/FBgn0069214.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic/first instar larval cuticle,germline clone,maternal effect,egg,pre-blastoderm embryo" FBgn0010106 ctw cut wing http://flybase.net/reports/FBgn0010106.html gene 16-Dec-15 2015_12 FBgn0263888 l(3)D24 http://flybase.net/reports/FBgn0263888.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0022744 anon-J7 anon-J7 http://flybase.net/reports/FBgn0022744.html gene J7 16-Dec-15 2015_12 FBgn0052654 Sec16 Sec16 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0052654.html "FBgn0030404, FBgn0030405, FBgn0061391" protein_coding_gene 0017016=Ras GTPase binding "0003400=regulation of COPII vesicle coating, 0070863=positive regulation of protein exit from endoplasmic reticulum, 0007029=endoplasmic reticulum organization, 0034198=cellular response to amino acid starvation, 0070973=protein localization to endoplasmic reticulum exit site, 0007030=Golgi organization" "0016020=membrane, 0070971=endoplasmic reticulum exit site" "sec26, CG2551, CG32654, dSec16, BcDNA:RE70141, Sec16, CG18079, sec16, dsec16" "IPR024880=COPII coat assembly protein, Sec16, IPR024298=Ancestral coatomer element 1, Sec16/Sec31" CG32654 16-Dec-15 2015_12 "WBGene00017419(F13B9.1),WBGene00013985(ZK512.5)" ENSMUSG00000026924(Sec16a) "ENSG00000148396(SEC16A),ENSG00000120341(SEC16B)" viable FBgn0265662 CR44469 http://flybase.net/reports/FBgn0265662.html non_protein_coding_gene lincRNA.932 CR44469 16-Dec-15 2015_12 FBgn0267161 CR45601 http://flybase.net/reports/FBgn0267161.html non_protein_coding_gene CR45601 16-Dec-15 2015_12 FBgn0065907 l(2)SH0190 lethal (2) SH0190 http://flybase.net/reports/FBgn0065907.html gene l(2)SH2 0190 16-Dec-15 2015_12 "lethal,recessive" FBgn0260722 CR42549 http://flybase.net/reports/FBgn0260722.html non_protein_coding_gene CR42549 16-Dec-15 2015_12 FBgn0267139 CR45579 http://flybase.net/reports/FBgn0267139.html non_protein_coding_gene lincRNA.749 CR45579 16-Dec-15 2015_12 FBgn0030336 CG1578 http://flybase.net/reports/FBgn0030336.html protein_coding_gene "IPR002761=Diphthamide synthase domain, IPR030662=Diphthine--ammonia ligase/Uncharacterised protein MJ0570, IPR006175=YjgF/YER057c/UK114 family, IPR013813=Endoribonuclease L-PSP/chorismate mutase-like, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG1578 16-Dec-15 2015_12 YLR143W() ENSXETG00000012897(ATPBD4) "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell DRSC19729 I 1.698509628 1.070807487 0.401884905 -0.256272057 -0.236248209 0.260020972 FBgn0034023 Ir52a Ionotropic receptor 52a http://flybase.net/reports/FBgn0034023.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 52a, DmelIR52a, IR52a, CG12960" CG12960 16-Dec-15 2015_12 viable FBgn0065206 l(2)SH2279 lethal (2) SH2279 http://flybase.net/reports/FBgn0065206.html gene l(2)SH2 2279 16-Dec-15 2015_12 "lethal,recessive" FBgn0058164 CG40164 http://flybase.net/reports/FBgn0058164.html FBan0040164 protein_coding_gene 16-Dec-15 2015_12 FBgn0265379 CR44320 http://flybase.net/reports/FBgn0265379.html non_protein_coding_gene lincRNA.859 CR44320 16-Dec-15 2015_12 FBgn0050345 CG30345 http://flybase.net/reports/FBgn0050345.html protein_coding_gene 0005215=transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG30345 16-Dec-15 2015_12 ENSDARG00000026149(slc46a1) YJL163C() "WBGene00021159(Y4C6B.5),WBGene00009582(F40F9.5),WBGene00012811(Y43F8A.5)" ENSXETG00000023785(SLC46A1) "ENSMUSG00000020829(Slc46a1),ENSMUSG00000029650(Slc46a3)" "ENSG00000076351(SLC46A1),ENSG00000139508(SLC46A3)" "viable,fertile" FBgn0265955 CR44742 http://flybase.net/reports/FBgn0265955.html non_protein_coding_gene lincRNA.44 CR44742 16-Dec-15 2015_12 FBgn0264303 CG43781 http://flybase.net/reports/FBgn0264303.html FBgn0035765 protein_coding_gene CG8600 CG43781 16-Dec-15 2015_12 "fertile,viable" FBgn0004792 sat satin http://flybase.net/reports/FBgn0004792.html FBgn0000998 gene "0007307=eggshell chorion gene amplification, 0007304=chorion-containing eggshell formation" fs(2)SC46 16-Dec-15 2015_12 female sterile FBgn0003966 vac vacuolated http://flybase.net/reports/FBgn0003966.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" wing FBgn0038672 CG6005 http://flybase.net/reports/FBgn0038672.html protein_coding_gene 0042060=wound healing CG6005 16-Dec-15 2015_12 ENSXETG00000009521(ARMC9) ENSMUSG00000062590(Armc9) ENSG00000135931(ARMC9) viable FBgn0060903 l(3)S043925b lethal (3) S043925b http://flybase.net/reports/FBgn0060903.html gene 0439/25 16-Dec-15 2015_12 "lethal,recessive" FBgn0010527 l(2)03050 lethal (2) 03050 http://flybase.net/reports/FBgn0010527.html gene 16-Dec-15 2015_12 "lethal,recessive,partially,rescuable maternal effect" embryonic/first instar larval cuticle FBgn0026340 Su(tor)2-187-2 Su(tor)2-187-2 http://flybase.net/reports/FBgn0026340.html gene 16-Dec-15 2015_12 FBgn0038432 CG14883 http://flybase.net/reports/FBgn0038432.html protein_coding_gene 0008889=glycerophosphodiester phosphodiesterase activity "0006629=lipid metabolic process, 0006071=glycerol metabolic process, 0048812=neuron projection morphogenesis" "IPR004129=Glycerophosphoryl diester phosphodiesterase, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG14883 16-Dec-15 2015_12 ENSDARG00000055108(zgc:56068) "WBGene00022532(ZC155.4),WBGene00011929(T22G5.1),WBGene00020446(T12B3.3),WBGene00011644(T09B9.3),WBGene00010092(F55C5.2)" ENSXETG00000021746(mir16) ENSMUSG00000033917(Gde1) ENSG00000006007(GDE1) viable FBgn0266398 CR45038 http://flybase.net/reports/FBgn0266398.html non_protein_coding_gene CR45038 16-Dec-15 2015_12 FBgn0069184 mcl(2)Z0198 mcl(2)Z0198 http://flybase.net/reports/FBgn0069184.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0037241 CG14646 http://flybase.net/reports/FBgn0037241.html "FBan0014646, FBgn0062060" protein_coding_gene anon-WO0118547.373 IPR018801=Putative transmembrane protein precursor CG14646 16-Dec-15 2015_12 WBGene00007941(C34F6.7) ENSXETG00000003875(TMEM129) ENSMUSG00000019295(Tmem129) ENSG00000168936(TMEM129) "viable,fertile" FBgn0023223 E(Egfr)C12 Enhancer of Egfr C12 http://flybase.net/reports/FBgn0023223.html gene 16-Dec-15 2015_12 FBgn0019904 anon-14Bf anon-14Bf http://flybase.net/reports/FBgn0019904.html gene ORF 16-Dec-15 2015_12 FBgn0260061 2L2816 http://flybase.net/reports/FBgn0260061.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0260586 2L2677 http://flybase.net/reports/FBgn0260586.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0010360 UVhs UV and heat shock response http://flybase.net/reports/FBgn0010360.html gene 16-Dec-15 2015_12 FBgn0266394 CR45034 http://flybase.net/reports/FBgn0266394.html non_protein_coding_gene CR45034 16-Dec-15 2015_12 FBgn0031207 CG13356 http://flybase.net/reports/FBgn0031207.html protein_coding_gene 0016491=oxidoreductase activity 16-Dec-15 2015_12 FBgn0261849 CG42781 http://flybase.net/reports/FBgn0261849.html protein_coding_gene MIP22495 CG42781 16-Dec-15 2015_12 FBgn0004079 Ars-region14 Autonomous replicating sequence region 14 http://flybase.net/reports/FBgn0004079.html region "Ars sequence 14, Ars14" 16-Dec-15 2015_12 FBgn0034219 mthl4 methuselah-like 4 http://flybase.net/reports/FBgn0034219.html "FBgn0046524, FBgn0046525" protein_coding_gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan, 0042594=response to starvation" 0016021=integral component of membrane "CG6536, anon-WO0170980.55, anon-WO0170980.56, methuselah-like 4, mth-like 4, Mth-like 4" "IPR017981=GPCR, family 2-like, IPR023311=Methuselah ectodomain, domain 2, IPR010596=Methuselah, N-terminal domain, IPR000832=GPCR, family 2, secretin-like" CG6536 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" FBgn0053317 CR33317 http://flybase.net/reports/FBgn0053317.html "FBgn0032903, FBgn0032905" pseudogene_attribute "CG18078, CG33317, CG18092, cg18092" CR33317 16-Dec-15 2015_12 FBgn0052227 gogo golden goal http://flybase.net/reports/FBgn0052227.html "FBgn0036961, FBgn0036963" protein_coding_gene 0004872=receptor activity "0007411=axon guidance, 0031290=retinal ganglion cell axon guidance, 0072499=photoreceptor cell axon guidance" "0030424=axon, 0005886=plasma membrane, 0016021=integral component of membrane, 0030426=growth cone" "Golden Goal, CT33316, CG13815, CG32227, Gogo, CG13817" "IPR000859=CUB domain, IPR000884=Thrombospondin type-1 (TSP1) repeat" CG32227 16-Dec-15 2015_12 "neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,somatic clone" "photoreceptor cell R8,medulla layer M1,transmedullary neuron Tm20,trichogen cell,mesothoracic tergum,medulla,somatic clone,lamina,photoreceptor cell R7,multidendritic neuron,photoreceptor cell" FBgn0026609 Abl::Hsap\ABL1::Hsap\BCR Abl::Hsap\ABL1::Hsap\BCR http://flybase.net/reports/FBgn0026609.html FBgn0024503 engineered_fusion_gene "Bcr-Abl, BcrAbl, Abl::Hsap\BCR, Bcr/Abl" 16-Dec-15 2015_12 "viable,fertile,visible,neuroanatomy defective" "presumptive embryonic/larval central nervous system,ventral nerve cord commissure,longitudinal connective,lens,eye,ommatidium,eye photoreceptor cell,rhabdomerehs.2sev,interommatidial bristle,secondary pigment cell,tertiary pigment cell,ventral adult lateral neuron & axonP2.4.Pdf,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,longitudinal connective | embryonic stage 16,midline crossing tract,ectopic,longitudinal connective | embryonic stage" FBgn0267637 CR45975 http://flybase.net/reports/FBgn0267637.html non_protein_coding_gene CR45975 16-Dec-15 2015_12 FBgn0005283 M(3)S35 Minute (3) S35 http://flybase.net/reports/FBgn0005283.html gene M(3)f 16-Dec-15 2015_12 "Minute,dominant,visible" macrochaeta FBgn0261934 dikar dikar http://flybase.net/reports/FBgn0261934.html "FBgn0052393, FBgn0035712, FBgn0052394" protein_coding_gene "0008355=olfactory learning, 0007616=long-term memory, 0007611=learning or memory" "Dikar, CG32394, CG32393, CG42799, CG10115" "IPR028942=WHIM1 domain, IPR001487=Bromodomain" CG42799 16-Dec-15 2015_12 ENSMUSG00000071226(Cecr2) """DRSC22261, DRSC09699"" " IE FBgn0052262 CG32262 http://flybase.net/reports/FBgn0052262.html FBgn0035463 protein_coding_gene 0016021=integral component of membrane CG10854 IPR007248=Mpv17/PMP22 CG32262 16-Dec-15 2015_12 YOR292C() ENSMUSG00000035559(Mpv17l2) ENSG00000127226 "partially lethal - majority die,some die during pupal stage" FBgn0047000 CG33946 putative noncoding RNA 008:3L http://flybase.net/reports/FBgn0047000.html FBgn0053946 protein_coding_gene "pncr008:3L, BcDNA:RH62830, CR33946" CG33946 16-Dec-15 2015_12 FBgn0031127 CG1835 http://flybase.net/reports/FBgn0031127.html "FBgn0044653, FBgn0063222" protein_coding_gene "anon-WO0140519.219, BcDNA:GH25431" CG1835 16-Dec-15 2015_12 viable FBgn0051475 CG31475 http://flybase.net/reports/FBgn0051475.html "FBgn0038687, FBgn0038688" protein_coding_gene 0005509=calcium ion binding 0048812=neuron projection morphogenesis "CG14281, CG3768" "IPR018247=EF-Hand 1, calcium-binding site, IPR027240=Calcium-binding protein CAB45, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG31475 16-Dec-15 2015_12 ENSDARG00000070682(sdf4) WBGene00016965(C56C10.9) ENSXETG00000001037(sdf4) ENSMUSG00000029076(Sdf4) ENSG00000078808(SDF4) FBgn0040669 CG14602 http://flybase.net/reports/FBgn0040669.html protein_coding_gene 16-Dec-15 2015_12 FBgn0060592 l(3)S093008 lethal (3) S093008 http://flybase.net/reports/FBgn0060592.html gene 0930/08 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0000425 DebA Developmental embryonic A http://flybase.net/reports/FBgn0000425.html protein_coding_gene 0005886=plasma membrane "CG17967, Deb-A, Deb" 16-Dec-15 2015_12 FBgn0000158 bam bag of marbles http://flybase.net/reports/FBgn0000158.html protein_coding_gene "0003730=mRNA 3'-UTR binding, 0000900=translation repressor activity, nucleic acid binding" "0001708=cell fate specification, 0048132=female germ-line stem cell asymmetric division, 0007140=male meiosis, 0030727=germarium-derived female germ-line cyst formation, 0030721=spectrosome organization, 0035212=cell competition in a multicellular organism, 0045479=vesicle targeting to fusome, 0030718=germ-line stem cell maintenance, 0017148=negative regulation of translation, 0042078=germ-line stem cell division, 0007282=cystoblast division, 0045478=fusome organization, 0007284=spermatogonial cell division, 0007283=spermatogenesis, 0098730=male germline stem cell symmetric division, 0007281=germ cell development, 0048477=oogenesis, 0007276=gamete generation, 0048135=female germ-line cyst formation, 0001709=cell fate determination" "0045170=spectrosome, 0045169=fusome, 0005737=cytoplasm" "Bag of marbles, transcript alpha, Bag-of-marbles, bag of marble, Bag-of-Marbles, fs(3)neo61, BamC, Bag of Marbles, BAM, ham, CG10422, bag-of-marbles, BamF, Bam, Bam-C, alpha" CG10422 16-Dec-15 2015_12 " spermatogenesis && adult stage , adult stage && oogenesis stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage S10 " " testis

, cystoblast

, ovary

, nurse cell

, centripetally migrating follicle cell

, cystocyte

" "female sterile,recessive,male semi-sterile,viable,fertile,male sterile,tumorigenic,increased cell number,wild-type,decreased cell number,heat sensitive,hyperplasia,cytokinesis defective,cell cycle defective,female fertile,poor" "ovary,ovariole,spermatid,spermatocyte cyst,spermatozoon,sperm individualization complex,egg chamber,germline cell,female,fusome,testis,spermatogonial cyst,male,hub cell,male germline stem cell,primary gonial cell,female germline stem cell,heat sensitive,germline cyst,germarium,ectopic,germarium & germ cell,cyst progenitor cell,male limited,spermatogonium,germline stem cell,female germline cell,germline clone,supernumerary,germarium cap cell,stem cell fusome,escort cell,escort stem cell,nurse cell fusome,cystoblast,spermatocyte" FBgn0267212 CR45652 http://flybase.net/reports/FBgn0267212.html non_protein_coding_gene CR45652 16-Dec-15 2015_12 FBgn0085647 CG41428 http://flybase.net/reports/FBgn0085647.html FBan0041428 protein_coding_gene 16-Dec-15 2015_12 FBgn0051460 CG31460 http://flybase.net/reports/FBgn0051460.html "FBgn0037597, FBgn0064862" protein_coding_gene "BcDNA:RE67710, CG11745" IPR018614=Uncharacterised protein family KRTCAP2 CG31460 16-Dec-15 2015_12 ENSDARG00000070386(zgc:153260) ENSMUSG00000042747(Krtcap2) ENSG00000163463(KRTCAP2) "viable,fertile" FBgn0035144 Kah Kahuli http://flybase.net/reports/FBgn0035144.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0000122=negative regulation of transcription from RNA polymerase II promoter 0000228=nuclear chromosome "scratch-like 1, scratch 3, CG17181, kahuli, kah" "IPR029794=Transcriptional repressor SCRATCH 1/2, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG17181 16-Dec-15 2015_12 "ENSXETG00000027366(TNeu114d14.1),ENSXETG00000024006(snai2)" "visible,viable,fertile" "eye,adult thorax,adult cuticle,chaeta" FBgn0266205 CR44900 http://flybase.net/reports/FBgn0266205.html non_protein_coding_gene CR44900 16-Dec-15 2015_12 FBgn0050509 tRNA:CR30509 transfer RNA:CR30509 http://flybase.net/reports/FBgn0050509.html "FBgn0050243, FBgn0060195" tRNA_gene 0033433=AUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "tRNA:I:AAT:AE002787-g, CR30243, chr2R.trna24-IleAAT, AE002787.trna42-IleAAT, CR30509" CR30509 16-Dec-15 2015_12 FBgn0086169 nkd::Btau\recoverin http://flybase.net/reports/FBgn0086169.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0001044 fs(3)HO115 female sterile (3) HO115 http://flybase.net/reports/FBgn0001044.html gene fs(3)115A 16-Dec-15 2015_12 female sterile oocyte FBgn0044415 Scim12 Sensitized chromosome inheritance modifier 12 http://flybase.net/reports/FBgn0044415.html gene 0016321=female meiosis chromosome segregation 0005634=nucleus 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant,mitotic cell cycle defective" "mitosis & nuclear chromosome,metaphase & condensed nuclear chromosome,nuclear chromosome" FBgn0003531 stmB stambha B http://flybase.net/reports/FBgn0003531.html gene stm-B 16-Dec-15 2015_12 "paralytic,recessive,heat sensitive" FBgn0024761 EC69 EC69 http://flybase.net/reports/FBgn0024761.html gene 16-Dec-15 2015_12 "enhancer of variegation,female,non-enhancer of variegation,male" FBgn0060892 l(3)S044612 lethal (3) S044612 http://flybase.net/reports/FBgn0060892.html gene 0446/12 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0264949 CR44118 http://flybase.net/reports/FBgn0264949.html non_protein_coding_gene CR44118 16-Dec-15 2015_12 FBgn0083986 CG34150 http://flybase.net/reports/FBgn0083986.html protein_coding_gene IPR008011=Complex 1 LYR protein CG34150 16-Dec-15 2015_12 ENSMUSG00000020268(Lyrm7) ENSG00000186687(LYRM7) FBgn0031177 CG14582 http://flybase.net/reports/FBgn0031177.html protein_coding_gene 16-Dec-15 2015_12 FBgn0023411 Ars-region42 Autonomous replicating sequence region 42 http://flybase.net/reports/FBgn0023411.html region "dARS42, Ars42" 16-Dec-15 2015_12 FBgn0053221 CR33221 http://flybase.net/reports/FBgn0053221.html FBgn0039556 pseudogene_attribute "CG33221, CG12260" CR33221 16-Dec-15 2015_12 FBgn0259112 CR42254 http://flybase.net/reports/FBgn0259112.html "FBgn0050478, FBgn0033965" non_protein_coding_gene "CG42254, CG12854, mdcds_11485, CR30478" CR42254 16-Dec-15 2015_12 FBgn0085777 CR40959 http://flybase.net/reports/FBgn0085777.html FBan0040959 rRNA_gene CR40959 16-Dec-15 2015_12 FBgn0001034 Fs(3)Far Farkas http://flybase.net/reports/FBgn0001034.html gene 0007344=pronuclear fusion "Far, Fs(3)Farkas, Fs(3)Sz8" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus | maternal effect,female pronucleus | maternal effect" FBgn0031700 CG14022 http://flybase.net/reports/FBgn0031700.html FBgn0062920 protein_coding_gene 0003998=acylphosphatase activity BcDNA:RH62365 "IPR001792=Acylphosphatase-like domain, IPR020456=Acylphosphatase" CG14022 16-Dec-15 2015_12 ENSXETG00000027759(acyp2) ENSMUSG00000060923(Acyp2) ENSG00000170634(ACYP2) "viable,body color defective" mesothoracic tergum FBgn0005312 ms(3)10R male sterile (3) 10R http://flybase.net/reports/FBgn0005312.html gene 16-Dec-15 2015_12 "male sterile,recessive,female sterile" "seminal vesicle,spermatid,spermatid & nucleus,spermatid axoneme,Nebenkern derivative,acrosomal granule" FBgn0016625 E(gl)2A Enhancer of glass 2A http://flybase.net/reports/FBgn0016625.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0029524 CG3176 http://flybase.net/reports/FBgn0029524.html FBgn0062924 protein_coding_gene BcDNA:RH59219 IPR022773=Siva CG3176 16-Dec-15 2015_12 ENSXETG00000024697(TEgg104k06.1) ENSMUSG00000064326(Siva1) DRSC18288 I 0.283302752 -2.077113422 -0.489477945 0.35674044 0.563331233 -0.477990687 FBgn0010909 msn misshapen http://flybase.net/reports/FBgn0010909.html "FBgn0010797, FBgn0024520, FBgn0035351" protein_coding_gene "0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0042656=JUN kinase kinase kinase kinase activity, 0008349=MAP kinase kinase kinase kinase activity, 0004674=protein serine/threonine kinase activity" "0007097=nuclear migration, 0007476=imaginal disc-derived wing morphogenesis, 0007411=axon guidance, 0009611=response to wounding, 0046529=imaginal disc fusion, thorax closure, 0007391=dorsal closure, 0016476=regulation of embryonic cell shape, 0007254=JNK cascade, 0001748=optic lobe placode development, 0046580=negative regulation of Ras protein signal transduction, 0006468=protein phosphorylation, 0001736=establishment of planar polarity, 0048477=oogenesis, 0000185=activation of MAPKKK activity, 0008360=regulation of cell shape, 0008594=photoreceptor cell morphogenesis" "0005938=cell cortex, 0070938=contractile ring" "Nik, JNKKKK, NIK, MESR5, DMSN, unnamed, l(3)06946, l(3)03349, HGK, l(3)6286, CG16973, Msn, mishappen, Mishappen, msm, l(3)j1E2, MSN, Misshapen, 6286" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR001180=Citron homology (CNH) domain" CG16973 16-Dec-15 2015_12 "ENSDARG00000035360(LOC100333250),ENSDARG00000056218(tnika),ENSDARG00000009031" YHR102W(KIC1) ENSXETG00000004324() "ENSMUSG00000020827(Mink1),ENSMUSG00000026074(Map4k4)" "ENSG00000071054(MAP4K4),ENSG00000154310(TNIK),ENSG00000141503(MINK1)" "lethal,partially lethal - majority die,recessive,neuroanatomy defective,maternal effect,poor,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,visible,planar polarity defective,somatic clone,wild-type,chemical sensitive" "lamina,photoreceptor cell | precursor & nucleusunspecified, msnDN.UAS,eye photoreceptor cell & axon,medulla,eye photoreceptor cell & growth cone,photoreceptor cell & axon,lamina plexus,embryonic/first instar larval cuticle,maternal effect,adult thorax,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,frontal ganglion,stomodeal nerve,microchaeta & scutumap-md544,wing hair,eye,ommatidium,rhabdomerehs.2sev,eye photoreceptor cell,ommatidial precursor cluster,eye photoreceptor cell & axonGMR.PF,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF,photoreceptor cell R6 & axonGMR.PF,photoreceptor cell R7 & axonGMR.PF,photoreceptor cell R8 & axonGMR.PF,intersegmental nerve,embryonic/larval salivary gland,axon69B, msnP656A,P659A.UAS,photoreceptor & axon69B, msnP656A,P659A.UAS,eye disc,somatic clone,rhabdomere,photoreceptor cell R4,photoreceptor cell | precursor & nucleus | somatic clone,photoreceptor & axon | somatic clone,lamina neuropil,dorsal,eye photoreceptor cell & axon | somatic clone,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,egg,precursor,wing disc,germline clone,neuron,dorsal closure embryo,embryonic segment,filamentous actin | dorsal closure stage,follicle cell,actin filament | somatic clone,egg chamber,photoreceptor cell | precursor & nucleusunspecified, msn03349,photoreceptor cell | precursor & nucleusunspecified,myosin II complex | dorsal closure stagee22c,embryonic leading edge cell,filamentous actin | dorsal closure stagee22c,myosin II complex | dorsal closure stageLE,filamentous actin | dorsal closure stageLE,ventral furrow,axon69B, msn102,photoreceptor & axon69B, msn102" FBgn0003301 rut rutabaga http://flybase.net/reports/FBgn0003301.html FBgn0044471 protein_coding_gene "0008294=calcium- and calmodulin-responsive adenylate cyclase activity, 0004016=adenylate cyclase activity" "0048675=axon extension, 0007186=G-protein coupled receptor signaling pathway, 0030431=sleep, 0007612=learning, 0007613=memory, 0008340=determination of adult lifespan, 0019933=cAMP-mediated signaling, 0007619=courtship behavior, 0048149=behavioral response to ethanol, 0009190=cyclic nucleotide biosynthetic process, 0006171=cAMP biosynthetic process, 0007614=short-term memory, 0090328=regulation of olfactory learning, 0007591=molting cycle, chitin-based cuticle, 0008355=olfactory learning, 0001661=conditioned taste aversion, 0007268=synaptic transmission, 0009408=response to heat, 0010738=regulation of protein kinase A signaling, 0008306=associative learning, 0007274=neuromuscular synaptic transmission, 0007625=grooming behavior, 0007617=mating behavior, 0007611=learning or memory, 0006979=response to oxidative stress, 0007528=neuromuscular junction development" "0005886=plasma membrane, 0016020=membrane, 0005887=integral component of plasma membrane" "unnamed, rutabage, CG9533, AC, Rutabaga, EP1603, RUT, Rut, Rut-AC, RUTABAGA, Ac12F" "IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR009398=Adenylate cyclase, conserved domain" CG9533 16-Dec-15 2015_12 WBGene00000071(acy-4) ENSXETG00000015663(ADCY1) ENSMUSG00000020431(Adcy1) ENSG00000164742(ADCY1) " adult stage , larval stage " " adult brain

, adult mushroom body

, mushroom body

, subesophageal ganglion

, optic lobe

" adult stage " mushroom body beta-lobe

, mushroom body gamma-lobe

, pedunculus

, optic lobe

, calyx of mushroom body

, adult brain

, subesophageal ganglion

, mushroom body

" "memory defective,learning defective,semidominant,neurophysiology defective,recessive,chemical sensitive,immune response defective,visual behavior defective,optomotor response defective,smell perception defective,taste perception defective,starvation stress response defective,neuroanatomy defective,locomotor behavior defective,drug conditional,lethal - all die before end of larval stage,some die during larval stage,behavior defective,thermotaxis behavior defective,sleep defective,viable" "neuromuscular junction,adult brain,axon & motor neuron | conditional ts,multidendritic neuron,embryonic/larval neuromuscular junction,macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval somatic muscle,growth cone & embryonic neuron,cell body & giant fibers,central nervous system,dense body,synapse,calyx of adult mushroom body,RP3 neuron & synapse,RP3 neuron & synaptic vesicle,neuromuscular junction | larval stage,neuromuscular junction & abdominal 4 ventral longitudinal muscle 4 & larva,neuromuscular junction & abdominal 4 ventral longitudinal muscle 3 & larva,varicosity | third instar larval stage,axon | third instar larval stage,neuromuscular junction | third instar larval stage,NMJ bouton,aCC neuron,RP2 motor neuron,supernumerary,NMJ bouton | larval stage" DRSC22976 K 0.8915598 2.983827794 FBgn0039676 ppk20 pickpocket 20 http://flybase.net/reports/FBgn0039676.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport "0016020=membrane, 0016021=integral component of membrane" "CG7577, PPK20" "IPR001873=Na+ channel, amiloride-sensitive" CG7577 16-Dec-15 2015_12 "viable,lethal" FBgn0051845 CR31845 http://flybase.net/reports/FBgn0051845.html non_protein_coding_gene CG31845 CR31845 16-Dec-15 2015_12 FBgn0033929 Tfb1 TFB1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0033929.html FBgn0010631 protein_coding_gene 0000990=core RNA polymerase binding transcription factor activity "0006289=nucleotide-excision repair, 0009411=response to UV, 0001113=transcriptional open complex formation at RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0001111=promoter clearance from RNA polymerase II promoter" "0005675=holo TFIIH complex, 0000439=core TFIIH complex, 0005634=nucleus" "TfBl, l(2)06949, CG8151, TFB1, l(2)06950, Tfb1, p62, Dmp62" "IPR013876=TFIIH p62 subunit, N-terminal, IPR005607=BSD domain, IPR027079=TFIIH subunit Tfb1/p62, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG8151 16-Dec-15 2015_12 ENSDARG00000026701(zgc:92126) YDR311W(TFB1) WBGene00019821(R02D3.3) ENSXETG00000018992(gtf2h1) ENSMUSG00000006599(Gtf2h1) ENSG00000110768(GTF2H1) embryonic stage -- adult stage "lethal,recessive,radiation sensitive,dominant,conditional,visible,partially lethal - majority die,some die during pupal stage" "adult cuticle,conditional,trichogen cell,mesothoracic tergum" DRSC07082 I -1.682262925 0.794798871 -0.641031415 -0.04223141 0.510236888 0.156893115 FBgn0011046 l(3)AFA7 lethal (3) AFA7 http://flybase.net/reports/FBgn0011046.html FBgn0005200 gene 16-Dec-15 2015_12 lethal FBgn0259324 C359 http://flybase.net/reports/FBgn0259324.html gene 16-Dec-15 2015_12 visible "wing,wing margin,chaeta" FBgn0259148 CG42263 http://flybase.net/reports/FBgn0259148.html protein_coding_gene CG42263 16-Dec-15 2015_12 FBgn0003577 su(sc)r "suppressor of scute, recessive" http://flybase.net/reports/FBgn0003577.html gene "su(sc), suppressor of scute" 16-Dec-15 2015_12 male sterile "wing,male" FBgn0020329 anon-6F7 anon-6F7 http://flybase.net/reports/FBgn0020329.html gene "unnamed, 6F7" 16-Dec-15 2015_12 FBgn0026265 bao beatoangelico http://flybase.net/reports/FBgn0026265.html gene 16-Dec-15 2015_12 FBgn0021786 l(3)02624 lethal (3) 02624 http://flybase.net/reports/FBgn0021786.html gene l(2)02624 16-Dec-15 2015_12 lethal FBgn0013943 E(var)3-201 E(var)3-201 http://flybase.net/reports/FBgn0013943.html gene 16-Dec-15 2015_12 FBgn0001887 l(2)21Da lethal (2) 21Da http://flybase.net/reports/FBgn0001887.html gene "l(2)neh1, l(2)neh-1" 16-Dec-15 2015_12 lethal FBgn0065108 ppk16 pickpocket 16 http://flybase.net/reports/FBgn0065108.html "FBgn0032146, FBgn0054059" protein_coding_gene 0005272=sodium channel activity "0006814=sodium ion transport, 0060025=regulation of synaptic activity" 0016021=integral component of membrane "CG34059, PPK16, CG4110, pickpocket16" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG34059 16-Dec-15 2015_12 "WBGene00016063(C24G7.1),WBGene00016064(acd-1),WBGene00009073(F23B2.3),WBGene00020903(T28F2.7),WBGene00016066(C24G7.4),WBGene00017879(F28A12.1),WBGene00001465(flr-1)" "ENSXETG00000012423(SCNN1G),ENSXETG00000027567(SCNN1B)" "ENSMUSG00000000216(Scnn1g),ENSMUSG00000030873(Scnn1b)" "ENSG00000166828(SCNN1G),ENSG00000168447(SCNN1B)" "neurophysiology defective,viable" FBgn0033196 CG1358 http://flybase.net/reports/FBgn0033196.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane FLVCR haem transporter "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG1358 16-Dec-15 2015_12 "ENSDARG00000031506(LOC100330297),ENSDARG00000038957(LOC565210),ENSDARG00000031587(flvcr1)" WBGene00015632(C09D4.1) "ENSXETG00000027282(TNeu125d23.1),ENSXETG00000014366(FLVCR1)" "ENSMUSG00000034258(Mfsd7c),ENSMUSG00000066595(Mfsd7b)" "ENSG00000119686(FLVCR2),ENSG00000162769(FLVCR1)" "viable,locomotor rhythm defective" DRSC06405 E -0.696118612 -0.878601477 -0.306235294 -2.177564499 0.541026459 0.095443917 FBgn0039009 CG13842 http://flybase.net/reports/FBgn0039009.html protein_coding_gene IPR026700=Coiled-coil domain-containing protein 142 CG13842 16-Dec-15 2015_12 viable FBgn0005483 l(1)ts1343 lethal (1) ts1343 http://flybase.net/reports/FBgn0005483.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0010020 E(Dl)9P39.3 Enhancer of Delta 9P39.3 http://flybase.net/reports/FBgn0010020.html gene 16-Dec-15 2015_12 FBgn0022132 l(2)k06402 lethal (2) k06402 http://flybase.net/reports/FBgn0022132.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043587 EP595a EP595a http://flybase.net/reports/FBgn0043587.html gene EP0595a 16-Dec-15 2015_12 FBgn0065215 l(2)SH2252 lethal (2) SH2252 http://flybase.net/reports/FBgn0065215.html gene l(2)SH2 2252 16-Dec-15 2015_12 "lethal,recessive" FBgn0043564 Su(hh)III Su(hh)III http://flybase.net/reports/FBgn0043564.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0066338 nov novichok http://flybase.net/reports/FBgn0066338.html gene "0007611=learning or memory, 0008355=olfactory learning" 16-Dec-15 2015_12 "learning defective,memory defective" FBgn0039165 CG6204 http://flybase.net/reports/FBgn0039165.html protein_coding_gene GH20028p IPR027417=P-loop containing nucleoside triphosphate hydrolase CG6204 16-Dec-15 2015_12 "ENSXETG00000003560(),ENSXETG00000007360()" ENSMUSG00000051278(4930422G04Rik) ENSG00000188014 viable DRSC15991 K 0.480711348 0.344115532 0.059433672 0.74330294 2.064624694 -0.040557557 FBgn0014056 Su(tor)2-4 Su(tor)2-4 http://flybase.net/reports/FBgn0014056.html gene 16-Dec-15 2015_12 eye FBgn0005183 l(2)S7 lethal of Seto 7 http://flybase.net/reports/FBgn0005183.html gene 16-Dec-15 2015_12 "sterile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032188 CG13137 http://flybase.net/reports/FBgn0032188.html protein_coding_gene "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG13137 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0265750 CR44557 http://flybase.net/reports/FBgn0265750.html non_protein_coding_gene CR44557 16-Dec-15 2015_12 FBgn0052655 CG32655 http://flybase.net/reports/FBgn0052655.html protein_coding_gene CG32655 16-Dec-15 2015_12 FBgn0003117 pnr pannier http://flybase.net/reports/FBgn0003117.html FBgn0038393 protein_coding_gene "0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0000983=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0001103=RNA polymerase II repressing transcription factor binding, 0046982=protein heterodimerization activity, 0008270=zinc ion binding, 0005515=protein binding, 0001085=RNA polymerase II transcription factor binding" "0048542=lymph gland development, 0045893=positive regulation of transcription, DNA-templated, 0061320=pericardial nephrocyte differentiation, 0007350=blastoderm segmentation, 0007498=mesoderm development, 0045892=negative regulation of transcription, DNA-templated, 0060047=heart contraction, 0008407=chaeta morphogenesis, 0007507=heart development, 0007179=transforming growth factor beta receptor signaling pathway, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042440=pigment metabolic process, 0035050=embryonic heart tube development, 0007389=pattern specification process, 0022416=chaeta development, 0030154=cell differentiation, 0007510=cardioblast cell fate determination, 0007398=ectoderm development, 0010002=cardioblast differentiation, 0035051=cardiocyte differentiation, 0002805=regulation of antimicrobial peptide biosynthetic process, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007391=dorsal closure, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "GATAa/Pannier, Pannier, CG3978, Pnr, PANNIER, dGATAa, PNR, CG3978-PA, l(3)89B3, dGATAa/pannier, GATA4, GATAa, GATA, prn" "IPR000679=Zinc finger, GATA-type, IPR013088=Zinc finger, NHR/GATA-type" CG3978 16-Dec-15 2015_12 "ENSDARG00000017821(gata5),ENSDARG00000035831,ENSDARG00000035759(gata4)" "ENSXETG00000000673(gata4),ENSXETG00000003144(gata6),ENSXETG00000005127(gata5)" "ENSMUSG00000021944(Gata4),ENSMUSG00000005836(Gata6),ENSMUSG00000015627(Gata5)" "ENSG00000136574(GATA4),ENSG00000141448(GATA6),ENSG00000130700(GATA5)" " embryonic stage | stage 11 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | stage 6-17 , embryonic stage | 2-12 hr , embryonic stage | stage 8 , embryonic stage | stage 13-15 , embryonic stage | stage 13 , larval stage | third instar stage 2 , larval stage | late third instar larval stage , embryonic stage | stage 6-9 " " dorsal ectoderm

, epidermis | restricted

, organism | 30-60% egg length & dorsal

, organism | 20-60% egg length

, epidermis | dorsal

, proctodeum | anterior to

, posterior spiracle primordium

, cardiogenic mesoderm

, dorsal mesothoracic disc | restricted

, amnioserosa

, eye-antennal disc | restricted

" "visible,somatic clone,cell non-autonomous,recessive,planar polarity defective,short lived,dominant,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,viable,fertile,poor" "embryonic/larval cuticle,cardioblast,embryonic pericardial cell,mesothoracic tergum,medial,somatic clone,adult abdomen,embryonic/larval lymph gland,heart primordium,scutellum,mesothoracic cleft,cardiogenic mesoderm,eye,dorsal,eye disc,photoreceptor cell,ectopic,cell non-autonomous,adult head,antenna,eye equator,embryonic dorsal epidermis,amnioserosa,anterior dorsocentral bristle,posterior dorsocentral bristle,adult heart,dorsocentral bristle,macrochaeta,supernumerary,dorsal medial muscle,scutellar bristle,anterior vertical bristle,postvertical bristle,head,adult thorax,chaeta,epidermis,embryonic garland cell,lymph gland primordium,wing vein,presutural bristle,embryonic epidermis,embryonic/larval pericardial cell,embryo,anterior orbital bristle,wing,scutum,sensory mother cell,embryonic/larval dorsal vessel,embryonic/larval somatic muscle,embryonic/larval visceral muscle,lateral,cell autonomous,microchaeta,postnotum,denticle belt,ventral nerve cord,sternite,tergite,posterior compartment,anterior compartment,embryonic/first instar larval cuticle" FBgn0015239 Hr78 Hormone-receptor-like in 78 http://flybase.net/reports/FBgn0015239.html protein_coding_gene "0003677=DNA binding, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding" "0048102=autophagic cell death, 0045089=positive regulation of innate immune response, 0007424=open tracheal system development, 0043401=steroid hormone mediated signaling pathway, 0050829=defense response to Gram-negative bacterium, 0035002=liquid clearance, open tracheal system, 0035071=salivary gland cell autophagic cell death, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "NR2D1, DHR78, X receptor at 78E/F, XR78E/F, HR78, CG7199, Dhr78, Hr78D" "IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001628=Zinc finger, nuclear hormone receptor-type" CG7199 16-Dec-15 2015_12 "ENSDARG00000045527(nr2c1),ENSDARG00000042477(nr2c2)" WBGene00022423(nhr-41) "ENSXETG00000023840(nr2c1),ENSXETG00000004817(NR2C2)" "ENSMUSG00000005893(Nr2c2),ENSMUSG00000005897(Nr2c1)" "ENSG00000177463(NR2C2),ENSG00000120798(NR2C1)" " larval stage&&prepupal stage , embryonic stage&&larval stage&&prepupal stage , embryonic stage , larval stage " "

ubiquitous , embryonic/larval salivary gland

" "wild-type,lethal - all die before end of larval stage,recessive,some die during larval stage,female semi-sterile,maternal effect,lethal,neuroanatomy defective,partially lethal - majority die,visible,body color defective,viable" "embryonic/larval tracheal system,embryonic/larval trachea,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000303 ChAT Choline acetyltransferase http://flybase.net/reports/FBgn0000303.html FBgn0064131 protein_coding_gene 0004102=choline O-acetyltransferase activity "0008292=acetylcholine biosynthetic process, 0007274=neuromuscular synaptic transmission" "CT23399, choline acetyl transferase, choline acetyltransferase, l(3)91Cc, Cholinacetyltransferase, Cat, DChAT, ChAt, Cha, CG12345, Choline-acetyltransferase, choline-O-acetyltransferase, dChAT, CHAT, ChaT, ChAT, cha, CLAT_DROME" IPR000542=Acyltransferase ChoActase/COT/CPT CG12345 16-Dec-15 2015_12 ENSDARG00000015854(chat) YML042W(CAT2) WBGene00000481(cha-1) ENSXETG00000005624(CHAT) ENSMUSG00000021919(Chat) ENSG00000070748(CHAT) adult stage "viable,fertile,phototaxis defective,lethal,recessive,wild-type,locomotor behavior defective,behavior defective,heat sensitive,neuroanatomy defective,somatic clone,neurophysiology defective,paralytic,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye photoreceptor cell & axon & stage 2 third instar larva | somatic clone | conditional ts,eye photoreceptor cell & axon & pupa | somatic clone | conditional ts,lamina anlage,cell non-autonomous,somatic clone,heat sensitive,aCC neuron,RP2 motor neuron,dorsal medial muscle,motor neuron,dendrite" FBgn0263842 CG43703 http://flybase.net/reports/FBgn0263842.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG43703 16-Dec-15 2015_12 FBgn0002357 l(3)87Ee lethal (3) 87Ee http://flybase.net/reports/FBgn0002357.html gene "G7, l(3)G7" 16-Dec-15 2015_12 "lethal,recessive,non-enhancer of variegation,non-suppressor of variegation" FBgn0261958 EU119 http://flybase.net/reports/FBgn0261958.html gene 16-Dec-15 2015_12 viable FBgn0034265 Snx16 Sorting nexin 16 http://flybase.net/reports/FBgn0034265.html protein_coding_gene "0035091=phosphatidylinositol binding, 0005515=protein binding" "0030510=regulation of BMP signaling pathway, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0030111=regulation of Wnt signaling pathway, 0001881=receptor recycling" "0005769=early endosome, 0005771=multivesicular body, 0031594=neuromuscular junction" "CG6410, DmSNX16, sorting nexin 16" IPR001683=Phox homologous domain CG6410 16-Dec-15 2015_12 ENSXETG00000010427(snx16) "neuroanatomy defective,viable,body color defective" "NMJ bouton,supernumerary,multivesicular body,mesothoracic tergum" FBgn0027380 Idefix\pol pol http://flybase.net/reports/FBgn0027380.html transposable_element_gene "0004190=aspartic-type endopeptidase activity, 0003676=nucleic acid binding" "0006508=proteolysis, 0015074=DNA integration" "pol, ORF2" "IPR001969=Aspartic peptidase, active site, IPR021109=Aspartic peptidase domain, IPR000477=Reverse transcriptase domain, IPR012337=Ribonuclease H-like domain, IPR001584=Integrase, catalytic core" 16-Dec-15 2015_12 FBgn0037697 GstZ2 Glutathione S transferase Z2 http://flybase.net/reports/FBgn0037697.html protein_coding_gene "0016034=maleylacetoacetate isomerase activity, 0004364=glutathione transferase activity" "0009072=aromatic amino acid family metabolic process, 0006559=L-phenylalanine catabolic process, 0006749=glutathione metabolic process, 0006572=tyrosine catabolic process" 0005737=cytoplasm "CG9363, cg9363, GSTZ2, gstz2" "IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal, IPR005955=Maleylacetoacetate isomerase" CG9363 16-Dec-15 2015_12 ENSDARG00000027984(zgc:92869) "WBGene00001790(gst-42),WBGene00001791(gst-43),WBGene00021817(Y53G8B.1)" ENSXETG00000011079(GSTZ1) ENSMUSG00000021033(Gstz1) ENSG00000100577(GSTZ1) FBgn0039178 CG6356 http://flybase.net/reports/FBgn0039178.html protein_coding_gene 0008513=secondary active organic cation transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG6356 16-Dec-15 2015_12 "YML123C(PHO84),YCR098C(GIT1)" viable FBgn0014115 anon-84Bd anon-84Bd http://flybase.net/reports/FBgn0014115.html gene X 16-Dec-15 2015_12 " embryonic stage | blastoderm , embryonic stage | stage 6 , embryonic stage | 0-6hr " " organism | 50-70% egg length

, thoracic segment

, cephalic furrow

, cephalic furrow | anterior to

, procephalic segment

, cephalic furrow | posterior to

" FBgn0033869 Cpr50Cb Cuticular protein 50Cb http://flybase.net/reports/FBgn0033869.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG6305, DmelCpr50Cb" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG6305 16-Dec-15 2015_12 viable FBgn0060520 l(3)S102611 lethal (3) S102611 http://flybase.net/reports/FBgn0060520.html gene 1026/11 16-Dec-15 2015_12 "lethal,recessive" FBgn0001831 l(1)ts445a lethal (1) ts445a http://flybase.net/reports/FBgn0001831.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0028277 l(1)G0424 lethal (1) G0424 http://flybase.net/reports/FBgn0028277.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022733 l(2)GPMG-14 lethal (2) GPMG-14 http://flybase.net/reports/FBgn0022733.html gene GPMG-14 16-Dec-15 2015_12 "lethal,recessive" FBgn0011784 l(3)05050 lethal (3) 05050 http://flybase.net/reports/FBgn0011784.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0267145 CR45585 http://flybase.net/reports/FBgn0267145.html non_protein_coding_gene CR45585 16-Dec-15 2015_12 FBgn0050435 CG30435 http://flybase.net/reports/FBgn0050435.html protein_coding_gene 16-Dec-15 2015_12 FBgn0002052 l(2)37Fe lethal (2) 37Fe http://flybase.net/reports/FBgn0002052.html gene l(2)E3 16-Dec-15 2015_12 lethal FBgn0042630 Sox21b Sox21b http://flybase.net/reports/FBgn0042630.html "FBgn0036412, FBgn0036413, FBgn0043569, FBgn0052139" protein_coding_gene "0008301=DNA binding, bending, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Sox B2-2, SoxB2.2, CG32139, sox-like, CG13483, CG6419, SOXB2.2" IPR009071=High mobility group box domain CG32139 16-Dec-15 2015_12 YKL032C(IXR1) WBGene00004771(sem-2) ENSMUSG00000061517(Sox21) "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC23005 K -1.699856266 -1.577460019 FBgn0019936 RpS20 Ribosomal protein S20 http://flybase.net/reports/FBgn0019936.html "FBgn0025315, FBgn0025320, FBgn0025322" protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" 0006412=translation "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "ribosomal protein S20, anon-EST:Posey122, anon-EST:Posey147, CG15693, Rps20, anon-EST:Posey111" "IPR005729=Ribosomal protein S10, eukaryotic/archaeal, IPR027486=Ribosomal protein S10 domain, IPR001848=Ribosomal protein S10, IPR018268=Ribosomal protein S10, conserved site" CG15693 16-Dec-15 2015_12 ENSDARG00000036044(rps20) YHL015W(RPS20) WBGene00004489(rps-20) ENSXETG00000005652(rps20) ENSMUSG00000028234(Rps20) ENSG00000008988(RPS20) embryonic stage

ubiquitous lethal DRSC16836 EK 0.282185572 1.008886325 1.67700678 -2.643814823 2.589184646 1.862470273 FBgn0053460 CG33460 http://flybase.net/reports/FBgn0053460.html "FBgn0034038, FBgn0050086" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG8215, SP41, CG30086, CR33460" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan" CG33460 16-Dec-15 2015_12 FBgn0262789 CR43170 http://flybase.net/reports/FBgn0262789.html pseudogene_attribute chr3LHet_2277384_2278053.0 CR43170 16-Dec-15 2015_12 FBgn0263410 CR43456 http://flybase.net/reports/FBgn0263410.html non_protein_coding_gene lincRNA.846 CR43456 16-Dec-15 2015_12 FBgn0065238 l(2)SH2161 lethal (2) SH2161 http://flybase.net/reports/FBgn0065238.html gene l(2)SH2 2161 16-Dec-15 2015_12 "lethal,recessive" FBgn0033529 CG17765 http://flybase.net/reports/FBgn0033529.html protein_coding_gene 0005509=calcium ion binding "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG17765 16-Dec-15 2015_12 ENSDARG00000023989(zgc:100787) ENSXETG00000017650(PEF1) ENSMUSG00000028779(Pef1) ENSG00000162517(PEF1) viable FBgn0259596 B1511 http://flybase.net/reports/FBgn0259596.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,arista" FBgn0266417 CG45057 http://flybase.net/reports/FBgn0266417.html "FBgn0036616, FBgn0085278, FBgn0266385" protein_coding_gene 0048812=neuron projection morphogenesis "mdcds_27436, CG34249, CG45027, HDC10482, CG4893" IPR008907=P25-alpha CG45057 16-Dec-15 2015_12 "ENSDARG00000030463(tppp3),ENSDARG00000035338(LOC559490),ENSDARG00000067585" WBGene00016321(C32E8.3) ENSXETG00000000345(TPPP3) "ENSMUSG00000014846(Tppp3),ENSMUSG00000021573(Tppp),ENSMUSG00000008813(Tppp2)" "ENSG00000159713(TPPP3),ENSG00000171368(TPPP),ENSG00000179636(TPPP2)" FBgn0250907 Cht3 Chitinase 3 http://flybase.net/reports/FBgn0250907.html "FBgn0022701, FBan0018140, FBgn0063117, FBgn0022703" protein_coding_gene "0008061=chitin binding, 0004568=chitinase activity" "0005975=carbohydrate metabolic process, 0006036=cuticle chitin catabolic process" 0005576=extracellular region "DmCHT1, DmCHT10, CHT3, chitinase-1, Cht1, Chitinase 1, chitinase-3, DmCHT3, CG18140, BcDNA:LP04696, Chitinase, CHT1, chitinase 3, Cht10, CG18140-PA3, CG17682" "IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR011583=Chitinase II, IPR029070=Chitinase insertion domain, IPR001579=Glycoside hydrolase, chitinase active site, IPR017853=Glycoside hydrolase superfamily, IPR002557=Chitin binding domain" CG18140 16-Dec-15 2015_12 WBGene00008842(F15A4.8) FBgn0005526 l(2)52ACc lethal (2) 52ACc http://flybase.net/reports/FBgn0005526.html gene unnamed 16-Dec-15 2015_12 FBgn0000304 chal chalice http://flybase.net/reports/FBgn0000304.html gene "0007297=ovarian follicle cell migration, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile "follicle cell,chorion,dorsal appendage" FBgn0263390 Nha2 Na+/H+ hydrogen antiporter 2 http://flybase.net/reports/FBgn0263390.html "FBgn0051052, FBgn0039032, FBgn0039035, FBgn0262841" protein_coding_gene "0015299=solute:proton antiporter activity, 0022821=potassium ion antiporter activity" "0009306=protein secretion, 0071805=potassium ion transmembrane transport, 0003096=renal sodium ion transport" "0005794=Golgi apparatus, 0016021=integral component of membrane, 0005903=brush border" "CG43205, CG31052, Transport and Golgi organization 12, CG43442, CG4693, CG4682, nha2, TANGO12, tango12, DmNHA2, DMG8-chr3R.34.001, Tango12" IPR006153=Cation/H+ exchanger CG43442 16-Dec-15 2015_12 "WBGene00009618(F41E7.2),WBGene00009617(F41E7.1),WBGene00010214(F57G8.5)" ENSXETG00000021321() FBgn0038498 beat-IIa beaten path IIa http://flybase.net/reports/FBgn0038498.html "FBgn0038497, FBgn0063055" protein_coding_gene "0016198=axon choice point recognition, 0007415=defasciculation of motor neuron axon, 0007155=cell adhesion, 0007275=multicellular organismal development, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules" "0005887=integral component of plasma membrane, 0005576=extracellular region" "CG14334, Beaten path IIa, CG14335, BcDNA:RE17794, CT33965, beat IIa, Beat-IIa" IPR003599=Immunoglobulin subtype CG14334 16-Dec-15 2015_12 "viable,fertile" FBgn0005642 wdn wings down http://flybase.net/reports/FBgn0005642.html "FBgn0003509, FBgn0004006, FBgn0004365" protein_coding_gene "0003677=DNA binding, 0046872=metal ion binding" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "serendipity-cognate, CG1454, pqp, Sryc, sry h-l, pourquoi-pas?, pourquoi-pas, sry-c, Serendipity cognate, sry-h1" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG1454 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | early " " oocyte

, nurse cell

" " adult stage && oogenesis stage | stage S1-6 , embryonic stage&&larval stage , adult stage && oogenesis stage | stage S9-10 , adult stage && oogenesis stage | stage >= S7 " " nurse cell

, oocyte

" "viable,fertile,wild-type,visible,recessive,lethal,maternal effect" "wing,maternal effect,anterior crossvein,posterior crossvein,dorsocentral bristle,postalar bristle,scutellar bristle" DRSC17095 E -1.144200891 0.886990845 -1.538075829 0.492230152 1.420399096 1.115790984 FBgn0065334 l(2)SH1866 lethal (2) SH1866 http://flybase.net/reports/FBgn0065334.html gene l(2)SH2 1866 16-Dec-15 2015_12 "lethal,recessive" FBgn0034517 Cpr57A Cuticular protein 57A http://flybase.net/reports/FBgn0034517.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG18066, Cpr57A" IPR000618=Insect cuticle protein CG18066 16-Dec-15 2015_12 viable FBgn0030641 CG6299 http://flybase.net/reports/FBgn0030641.html protein_coding_gene "0017089=glycolipid transporter activity, 0051861=glycolipid binding" 0046836=glycolipid transport 0005737=cytoplasm IPR014830=Glycolipid transfer protein domain CG6299 16-Dec-15 2015_12 ENSDARG00000061921(gltp) ENSXETG00000018625(GLTP) ENSMUSG00000011884(Gltp) ENSG00000139433(GLTP) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0036766 CG5506 http://flybase.net/reports/FBgn0036766.html FBgn0063082 protein_coding_gene BcDNA:LP12049 "IPR024518=Domain of unknown function DUF3421, IPR006616=DM9 repeat" CG5506 16-Dec-15 2015_12 viable FBgn0036381 CG8745 http://flybase.net/reports/FBgn0036381.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0004587=ornithine-oxo-acid transaminase activity, 0008453=alanine-glyoxylate transaminase activity" "0019544=arginine catabolic process to glutamate, 0035094=response to nicotine" 0005739=mitochondrion "IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR005814=Aminotransferase class-III, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG8745 16-Dec-15 2015_12 "ENSDARG00000035544(agxt2l1),ENSDARG00000040566(zgc:123007)" WBGene00020139(T01B11.2) ENSXETG00000021098(AGXT2L1) "ENSMUSG00000019232(Agxt2l1),ENSMUSG00000020359(Agxt2l2)" "ENSG00000164089(AGXT2L1),ENSG00000175309(AGXT2L2)" viable FBgn0033178 CG11127 http://flybase.net/reports/FBgn0033178.html protein_coding_gene CG11127 16-Dec-15 2015_12 viable FBgn0002847 msf misformed http://flybase.net/reports/FBgn0002847.html gene 16-Dec-15 2015_12 "visible,recessive" "wing,leg,eye" FBgn0005021 Darkened-eye Darkened eye http://flybase.net/reports/FBgn0005021.html gene Dke 16-Dec-15 2015_12 "eye color defective,dominant,lethal,recessive" "pigment cell,ommatidium" FBgn0262140 CG42866 http://flybase.net/reports/FBgn0262140.html protein_coding_gene CG42866 16-Dec-15 2015_12 FBgn0065685 l(2)SH0659 lethal (2) SH0659 http://flybase.net/reports/FBgn0065685.html gene l(2)SH2 0659 16-Dec-15 2015_12 "lethal,recessive" FBgn0087003 tal tarsal-less http://flybase.net/reports/FBgn0087003.html "FBgn0053327, FBgn0047214, FBgn0082915, FBgn0041592, FBgn0028207" gene_with_polycistronic_transcript "0002009=morphogenesis of an epithelium, 0009792=embryo development ending in birth or egg hatching, 0045604=regulation of epidermal cell differentiation, 0002064=epithelial cell development, 0035107=appendage morphogenesis, 0016348=imaginal disc-derived leg joint morphogenesis, 0007015=actin filament organization, 0007424=open tracheal system development, 0008593=regulation of Notch signaling pathway, 0032231=regulation of actin filament bundle assembly, 0030162=regulation of proteolysis" "BcDNA:LD11162, polished rice, tarsalless, MRE29, CR33327, lethal (3) S011041, pncr001:3R, l(3)S011041, pri, tal, tarsel-less, pncr001:3, npcr001:3R, putative noncoding RNA 001:3R" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal,recessive,visible,somatic clone" "tarsal segment,leg,sex comb,ectopic,tibia,metatarsus,cephalopharyngeal skeleton,embryonic head,joint,somatic clone,ventral thoracic disc,tracheal branch primordium,denticle belt,denticle,posterior spiracle primordium,dorsal hair,embryonic/larval posterior spiracle,taenidial fold,embryonic/larval dorsal branch,embryonic/larval transverse connective,embryonic/larval trachea,external sensory organ,mesothoracic tergum,wing vein L3,wing vein,leg sensillum" FBgn0267828 Fatp Fatty acid (long chain) transport protein http://flybase.net/reports/FBgn0267828.html "FBgn0021953, FBgn0032263, FBgn0061183, FBgn0266458" protein_coding_gene "0003824=catalytic activity, 0005324=long-chain fatty acid transporter activity" "0070328=triglyceride homeostasis, 0015909=long-chain fatty acid transport, 0008152=metabolic process" "0012505=endomembrane system, 0005886=plasma membrane" "CG7400, anon-WO0121795.74, Dromel_CG7400_FBtr0080133_fatp_uORF, fatty acid transport protein, CG46149, dFATP, l(2)k10307, Fatty acid transport protein, Dromel_CG7400_FBtr0080133_fatp_mORF, CG45083, fatp, dFatp" "IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site, IPR025110=AMP-binding enzyme C-terminal domain" CG46149 16-Dec-15 2015_12 "ENSDARG00000017047(zgc:112138),ENSDARG00000006240(slc27a1),ENSDARG00000038352(LOC100333606)" YBR041W(FAT1) "WBGene00017012(acs-22),WBGene00009218(acs-20)" "ENSXETG00000023888(),ENSXETG00000016111(Q4QQR1_XENTR),ENSXETG00000008282(SLC27A6)" "ENSMUSG00000031808(Slc27a1),ENSMUSG00000059316(Slc27a4)" "ENSG00000130304(SLC27A1),ENSG00000167114(SLC27A4)" "lethal,recessive,neurophysiology defective,cell autonomous,somatic clone,conditional,feeding behavior defective,dominant,long lived,female,heat stress response defective,male limited,cold stress response defective,female limited,oxidative stress response defective,starvation stress response defective,viable,partially lethal - majority die" "eye photoreceptor cell,somatic clone,cell autonomous,conditional,adult heart" FBgn0028902 Tektin-A Tektin A http://flybase.net/reports/FBgn0028902.html FBgn0044635 protein_coding_gene 0008017=microtubule binding 0007017=microtubule-based process 0005875=microtubule associated complex "Tektin-A, anon-WO0140519.235, BG:DS02252.2, TEKTIN A, CG4767" IPR000435=Tektin CG4767 16-Dec-15 2015_12 ENSDARG00000028899(zgc:162848) WBGene00019828(R02E12.4) viable FBgn0003321 sbr small bristles http://flybase.net/reports/FBgn0003321.html "FBgn0030236, FBgn0030238" protein_coding_gene "0000166=nucleotide binding, 0003723=RNA binding" "0006378=mRNA polyadenylation, 0051168=nuclear export, 0016973=poly(A)+ mRNA export from nucleus, 0007616=long-term memory, 0030534=adult behavior, 0006406=mRNA export from nucleus" "0005635=nuclear envelope, 0005737=cytoplasm, 0031965=nuclear membrane, 0005654=nucleoplasm" "locus 1, nxf1, NXF1-p15, nuclear export factor 1, DmNXF1, CG17335, Dm nxf1, DNXF-1, sbt, NXF1, PABPr, l(1)G1, CG1664, shorter-bristles, l(1)9Fd, l(1)ts, dTap, NFX1, Nxf1, CT4634, l(1)ts403" "IPR001611=Leucine-rich repeat, IPR009060=UBA-like, IPR005637=TAP C-terminal (TAP-C) domain, IPR015245=Nuclear RNA export factor Tap, RNA-binding domain, IPR030217=Nuclear RNA export factor, IPR002075=Nuclear transport factor 2, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR018222=Nuclear transport factor 2, eukaryote" CG1664 16-Dec-15 2015_12 "ENSDARG00000055076(nxf1),ENSDARG00000009898" YPL169C(MEX67) "WBGene00003834(nxf-1),WBGene00003835(nxf-2)" ENSXETG00000019442(nxf1) "ENSMUSG00000010097(Nxf1),ENSMUSG00000031410(Nxf7),ENSMUSG00000009941(Nxf2),ENSMUSG00000057000(Nxf3)" "ENSG00000162231(NXF1),ENSG00000185945(NXF2B),ENSG00000185554(NXF2),ENSG00000147206(NXF3),ENSG00000126952(NXF5)" "lethal,heat sensitive,visible,viable,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,recessive,male sterile,female sterile,meiotic cell cycle defective,semidominant,partially,sterile,memory defective,germline clone,somatic clone,small body,mitotic cell cycle defective,male,reduced,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "muscle attachment site,intersegmental nerve,macrochaeta,primary spermatocyte cyst,axoneme,meiosis & nuclear chromosome,scutellar bristle,mesothoracic bristle,metathoracic bristle,head bristle,leg,wing,longitudinal connective,egg chamber,germline clone,somatic clone,embryonic somatic muscle,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4" DRSC20368 IEK 2.191213222 -0.665544386 1.739542964 -0.478426527 0.738271394 1.702083552 FBgn0002284 Prosë_6 Proteasome ë_6 subunit http://flybase.net/reports/FBgn0002284.html FBgn0010150 protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0005839=proteasome core complex, 0000502=proteasome complex" "Proteasome 26kD subunit, Prosbeta6, l(3)DTS-5, Beta-6, Pros26-DTS, Pros26, Proteasome subunit 20S, pros26beta6, pros26B, b6, beta6 proteosome subunit, l(3)73Ai, DTS-5, PSMB1, pros26, 20S proteasome, CG4097, beta6_dm, PSB1_DROME, beta6, l(3)DTS5, beta-6, DTS5" "IPR016050=Proteasome beta-type subunit, conserved site, IPR001353=Proteasome, subunit alpha/beta, IPR023333=Proteasome B-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal" CG4097 16-Dec-15 2015_12 ENSDARG00000009640(psmb1) YBL041W(PRE7) WBGene00003952(pbs-6) ENSXETG00000008557(psmb1) ENSMUSG00000014769(Psmb1) ENSG00000008018(PSMB1) "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,heat sensitive,dominant,visible,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,hypoactive" "macrochaeta,tormogen cell,ectopic,thecogen cell,eo neuron,trichogen cell,eye,ommatidial precursor cluster,heat sensitive,microchaeta,imaginal disc,adult abdomen,adult head,wing vein,socket,eo sensory structure,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,abdominal sternite 6,ommatidium" DRSC11256 IEK -2.262374369 -2.258087669 -0.230988713 -3.380115822 1.641247707 0.286082559 FBgn0039792 CG2267 http://flybase.net/reports/FBgn0039792.html FBgn0044711 protein_coding_gene anon-WO0140519.167 CG2267 16-Dec-15 2015_12 viable FBgn0051016 CG31016 http://flybase.net/reports/FBgn0051016.html FBgn0039791 protein_coding_gene "0005506=iron ion binding, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, 0004656=procollagen-proline 4-dioxygenase activity, 0031418=L-ascorbic acid binding" "0055114=oxidation-reduction process, 0018401=peptidyl-proline hydroxylation to 4-hydroxy-L-proline, 0032504=multicellular organism reproduction" "0016222=procollagen-proline 4-dioxygenase complex, 0005783=endoplasmic reticulum" CG9708 "IPR006620=Prolyl 4-hydroxylase, alpha subunit, IPR011990=Tetratricopeptide-like helical domain, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG31016 16-Dec-15 2015_12 viable FBgn0265952 CR44739 http://flybase.net/reports/FBgn0265952.html non_protein_coding_gene lincRNA.190 CR44739 16-Dec-15 2015_12 FBgn0038035 lig3 DNA ligase III http://flybase.net/reports/FBgn0038035.html protein_coding_gene "0003910=DNA ligase (ATP) activity, 0005524=ATP binding, 0003677=DNA binding" "0071897=DNA biosynthetic process, 0051103=DNA ligation involved in DNA repair, 0006266=DNA ligation, 0006273=lagging strand elongation, 0006310=DNA recombination, 0006289=nucleotide-excision repair" "0005739=mitochondrion, 0005694=chromosome, 0005634=nucleus" "lig 3, Lig3, LIG3, CG17227, ligase III" "IPR001357=BRCT domain, IPR012308=DNA ligase, ATP-dependent, N-terminal, IPR012340=Nucleic acid-binding, OB-fold, IPR000977=DNA ligase, ATP-dependent, IPR012310=DNA ligase, ATP-dependent, central, IPR016059=DNA ligase, ATP-dependent, conserved site, IPR012309=DNA ligase, ATP-dependent, C-terminal" CG17227 16-Dec-15 2015_12 ENSDARG00000052553(zgc:112973) ENSXETG00000019634(LIG3) ENSMUSG00000020697(Lig3) ENSG00000005156(LIG3) "viable,fertile" FBgn0041622 Or69a Odorant receptor 69a http://flybase.net/reports/FBgn0041622.html "FBgn0053264, FBgn0036326, FBgn0052116" protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" 0007608=sensory perception of smell "0016021=integral component of membrane, 0032590=dendrite membrane" "or69a, CG17902, Or69b, 69a, Odorant receptor 69b, 69b, DOR83, 69F.1, Or69ab, Or69A, CG32116, CG33264, Or69aA, Or69aB, DOR82" "IPR004117=Olfactory receptor, Drosophila" CG33264 16-Dec-15 2015_12 viable FBgn0069421 JJF077 JJF077 http://flybase.net/reports/FBgn0069421.html gene 16-Dec-15 2015_12 stress response defective FBgn0053406 5SrRNA:CR33406 5SrRNA:CR33406 http://flybase.net/reports/FBgn0053406.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33406 CR33406 16-Dec-15 2015_12 FBgn0034743 RpS16 Ribosomal protein S16 http://flybase.net/reports/FBgn0034743.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0022627=cytosolic small ribosomal subunit, 0005840=ribosome" "S16, CG4046, Rp S16, bs32d05.y1" "IPR020568=Ribosomal protein S5 domain 2-type fold, IPR000754=Ribosomal protein S9, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR020574=Ribosomal protein S9, conserved site" CG4046 16-Dec-15 2015_12 ENSDARG00000045487(rps16) "YDL083C(RPS16B),YMR143W(RPS16A)" WBGene00004485(rps-16) ENSXETG00000018809(rps16) "ENSMUSG00000060419(Rps16-ps2),ENSMUSG00000037563(Rps16)" ENSG00000105193(RPS16) lethal DRSC04442 EK -1.305202557 -1.279659626 -0.366458655 -2.632320288 1.560714645 3.790963013 FBgn0039952 CG17879 http://flybase.net/reports/FBgn0039952.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266264 CR44959 http://flybase.net/reports/FBgn0266264.html non_protein_coding_gene CR44959 16-Dec-15 2015_12 FBgn0067651 sd-4 sd-4 http://flybase.net/reports/FBgn0067651.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 4 16-Dec-15 2015_12 "viable,neurophysiology defective,somatic clone,phototaxis defective" FBgn0025335 CG4585 http://flybase.net/reports/FBgn0025335.html protein_coding_gene "anon-60Ab, unnamed, undefined 2, dCCS4, CK00282, UD2" CG4585 16-Dec-15 2015_12 viable DRSC04475 E 0.14897857 0.367915066 2.440009505 -0.664420502 0.023270135 -0.708386497 FBgn0065424 l(2)SH1516 lethal (2) SH1516 http://flybase.net/reports/FBgn0065424.html gene l(2)SH2 1516 16-Dec-15 2015_12 "lethal,recessive" FBgn0066356 l(3)128 lethal (3) 128 http://flybase.net/reports/FBgn0066356.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0262441 mir-313 mir-313 stem loop http://flybase.net/reports/FBgn0262441.html "FBgn0067691, FBgn0262296" miRNA_gene "0035282=segmentation, 0007390=germ-band shortening, 0050803=regulation of synapse structure or activity, 0008258=head involution" "mIR-310s, Dme-miR-313, mIR-31, CR43003, mir-313, CR33617, dme-miR-313, dme-mir-313, miR-313" CR43003 16-Dec-15 2015_12 "viable,visible,lethal,partially lethal - majority die" "wing,wing vein,wing margin,ectopic" FBgn0265844 CR44633 http://flybase.net/reports/FBgn0265844.html non_protein_coding_gene CR44633 16-Dec-15 2015_12 FBgn0040047 CG17413 http://flybase.net/reports/FBgn0040047.html protein_coding_gene 16-Dec-15 2015_12 FBgn0022276 l(2)45Ai lethal (2) 45Ai http://flybase.net/reports/FBgn0022276.html gene l(2)k00116 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038742 Arc42 Arc42 http://flybase.net/reports/FBgn0038742.html protein_coding_gene "0003995=acyl-CoA dehydrogenase activity, 0050660=flavin adenine dinucleotide binding, 0001104=RNA polymerase II transcription cofactor activity" "0048813=dendrite morphogenesis, 0006367=transcription initiation from RNA polymerase II promoter, 0055114=oxidation-reduction process" 0016592=mediator complex "dARC42, CG4703" "IPR009075=Acyl-CoA dehydrogenase/oxidase C-terminal, IPR013786=Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR006089=Acyl-CoA dehydrogenase, conserved site, IPR009100=Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR006091=Acyl-CoA oxidase/dehydrogenase, central domain" CG4703 16-Dec-15 2015_12 ENSDARG00000030781(acads) ENSXETG00000012275(acads) ENSMUSG00000029545(Acads) ENSG00000122971(ACADS) "visible,viable,fertile" wing DRSC14340 I 1.823805719 -0.129825336 1.436923689 0.174879457 -0.592074067 -0.423361034 FBgn0038539 Atg8b Autophagy-related 8b http://flybase.net/reports/FBgn0038539.html protein_coding_gene 0031386=protein tag 0016236=macroautophagy 0005776=autophagic vacuole "Atg8, Autophagy-specific gene 8b, unnamed, ATG8, Atg8B, autophagy-specific gene 8b, autophagy related gene 8, ATG8b, CG12334, atg8b, atg8B" "IPR029071=Ubiquitin-related domain, IPR004241=Autophagy protein Atg8 ubiquitin-like" CG12334 16-Dec-15 2015_12 YBL078C(ATG8) viable FBgn0004740 l(3)85Dg lethal (3) 85Dg http://flybase.net/reports/FBgn0004740.html gene 16-Dec-15 2015_12 lethal FBgn0062587 Mod(var)1657 Mod(var)1657 http://flybase.net/reports/FBgn0062587.html gene 0006342=chromatin silencing 1657 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0028099 l(3)S073002a lethal (3) S073002a http://flybase.net/reports/FBgn0028099.html gene "l(3)S073002, 1382/10, 1152/14, 1323/04" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000784 fs(1)A1561 female sterile (1) A1561 http://flybase.net/reports/FBgn0000784.html gene fs(1)1561 16-Dec-15 2015_12 female sterile soma-dependent FBgn0028939 NimC2 Nimrod C2 http://flybase.net/reports/FBgn0028939.html FBgn0032541 protein_coding_gene 0006909=phagocytosis 0016021=integral component of membrane "nimrod C2, CT40902, nimC2, NimC2, CG18146, DS00180.14, BG:DS00180.14, CG18146-PB" "IPR003341=Cysteine rich repeat, tripleX, IPR000742=EGF-like domain" CG18146 16-Dec-15 2015_12 ENSDARG00000039652(LOC100004638) "WBGene00018026(F35A5.4),WBGene00004104(pqn-13),WBGene00008559(F07H5.8)" ENSMUSG00000044476 viable FBgn0020325 anon-73DFa anon-73DFa http://flybase.net/reports/FBgn0020325.html gene 521 16-Dec-15 2015_12 FBgn0027273 l(1)G0203 lethal (1) G0203 http://flybase.net/reports/FBgn0027273.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0263661 CR43652 http://flybase.net/reports/FBgn0263661.html non_protein_coding_gene CR43652 16-Dec-15 2015_12 FBgn0065438 l(2)SH1468 lethal (2) SH1468 http://flybase.net/reports/FBgn0065438.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001656 l(1)ds10 lethal (1) discs small 10 http://flybase.net/reports/FBgn0001656.html gene l(1)1-74 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" imaginal disc FBgn0262177 mir-375 mir-375 stem loop http://flybase.net/reports/FBgn0262177.html miRNA_gene "dme-miR-375-3p, dme-miR-375, miR-375, CR42884, dme-mir-375" CR42884 16-Dec-15 2015_12 "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" wing FBgn0032222 CG5037 http://flybase.net/reports/FBgn0032222.html protein_coding_gene 0008495=protoheme IX farnesyltransferase activity "0006783=heme biosynthetic process, 0008535=respiratory chain complex IV assembly, 0048034=heme O biosynthetic process" 0016021=integral component of membrane "Protoheme IX farnesyltransferase, COXX" "IPR006369=Protohaem IX farnesyltransferase, IPR000537=UbiA prenyltransferase family, IPR030470=UbiA prenyltransferase conserved site" CG5037 16-Dec-15 2015_12 ENSDARG00000034309(cox10) YPL172C(COX10) WBGene00012895(Y46G5A.2) ENSMUSG00000042148(Cox10) ENSG00000006695(COX10) "viable,fertile,visible" trichogen cell FBgn0010863 l(3)05279 lethal (3) 05279 http://flybase.net/reports/FBgn0010863.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003603 Su(var)3-12 Suppressor of variegation 3-12 http://flybase.net/reports/FBgn0003603.html gene "Su-var(3)12, Suvar(3)12" 16-Dec-15 2015_12 FBgn0036618 Cpr72Eb Cuticular protein 72Eb http://flybase.net/reports/FBgn0036618.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix CG12255 "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG12255 16-Dec-15 2015_12 "viable,fertile" FBgn0264948 CR44117 http://flybase.net/reports/FBgn0264948.html non_protein_coding_gene CR44117 16-Dec-15 2015_12 FBgn0044026 PK11 Pocket 11 http://flybase.net/reports/FBgn0044026.html gene 0050909=sensory perception of taste 16-Dec-15 2015_12 FBgn0266445 CG45075 http://flybase.net/reports/FBgn0266445.html FBgn0042122 protein_coding_gene "CG18783, CG9167" CG45075 16-Dec-15 2015_12 FBgn0024681 l(1)LefEM20 lethal (1) LefEM20 http://flybase.net/reports/FBgn0024681.html gene EM20 16-Dec-15 2015_12 FBgn0020578 anon-59Cg anon-59Cg http://flybase.net/reports/FBgn0020578.html gene 16-Dec-15 2015_12 FBgn0016878 l(2)39DEc lethal (2) 39DEc http://flybase.net/reports/FBgn0016878.html gene D490 16-Dec-15 2015_12 lethal FBgn0022968 snRNPD-L snRNPD-L http://flybase.net/reports/FBgn0022968.html gene "0030532=small nuclear ribonucleoprotein complex, 0005634=nucleus" D[L] 16-Dec-15 2015_12 FBgn0052476 mthl14 methuselah-like 14 http://flybase.net/reports/FBgn0052476.html FBgn0047120 protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "CG32476, BcDNA:RE31310" CG32476 16-Dec-15 2015_12 viable FBgn0010153 l(3)tl lethal (3) tumorous larvae http://flybase.net/reports/FBgn0010153.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,recessive,lethal - all die before end of larval stage,some die during larval stage" "larval salivary gland & embryo & polytene chromosome,embryonic/larval fat body,embryonic/larval digestive system,melanotic mass,embryonic/larval hemocyte" FBgn0085303 CG34274 http://flybase.net/reports/FBgn0085303.html protein_coding_gene IPR011990=Tetratricopeptide-like helical domain CG34274 16-Dec-15 2015_12 WBGene00016375(C33H5.8) FBgn0261607 M(2)28DE Minute (2) 28DE http://flybase.net/reports/FBgn0261607.html gene 16-Dec-15 2015_12 FBgn0065366 l(2)SH1719 lethal (2) SH1719 http://flybase.net/reports/FBgn0065366.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0037199 CG11137 http://flybase.net/reports/FBgn0037199.html FBgn0063146 protein_coding_gene 0012505=endomembrane system "CT31141, BcDNA:LD31024" "IPR009445=Protein of unknown function DUF1077, TMEM85" CG11137 16-Dec-15 2015_12 YGL231C(EMC4) WBGene00022776(ZK616.6) ENSXETG00000017003(BC059737.1) ENSMUSG00000027131(Tmem85) ENSG00000128463(TMEM85) viable FBgn0029999 CG1575 http://flybase.net/reports/FBgn0029999.html protein_coding_gene "IPR016024=Armadillo-type fold, IPR024679=Pre-rRNA-processing protein IPI1/Testis-expressed sequence 10 protein" CG1575 16-Dec-15 2015_12 ENSDARG00000055885(tex10) ENSMUSG00000028345(Tex10) ENSG00000136891(TEX10) "viable,visible" "trichogen cell,mesothoracic tergum" DRSC18069 K -1.053744179 0.514752277 -0.351634025 0.299704524 -1.513680532 -0.017940009 FBgn0005305 ms(1)202 male sterile (1) 202 http://flybase.net/reports/FBgn0005305.html gene 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective" "meiotic cell cycle | male,meiotic cell cycle & nuclear chromosome | male,meiotic cell cycle & spindle | male" FBgn0036760 CG5567 http://flybase.net/reports/FBgn0036760.html protein_coding_gene "0016791=phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0004035=alkaline phosphatase activity" 0006470=protein dephosphorylation "0005737=cytoplasm, 0005634=nucleus" "Phos5567, 24666141" "IPR006357=HAD-superfamily hydrolase, subfamily IIA, IPR023215=Nitrophenylphosphatase-like domain, IPR023214=HAD-like domain, IPR006349=2-phosphoglycolate phosphatase, eukaryotic" CG5567 16-Dec-15 2015_12 "ENSDARG00000029695(pgp),ENSDARG00000038315(zgc:194409)" YDL236W(PHO13) "WBGene00016892(C53A3.2),WBGene00019604(K09H11.7),WBGene00018424(F44E7.2)" ENSXETG00000016097(PGP) "ENSMUSG00000043445(Pgp),ENSMUSG00000068221(Pdxp)" "ENSG00000184207(PGP),ENSG00000221912" viable FBgn0004885 tok tolkin http://flybase.net/reports/FBgn0004885.html protein_coding_gene "0008270=zinc ion binding, 0004872=receptor activity, 0005509=calcium ion binding, 0004222=metalloendopeptidase activity" "0006898=receptor-mediated endocytosis, 0008045=motor neuron axon guidance, 0008586=imaginal disc-derived wing vein morphogenesis, 0010629=negative regulation of gene expression, 0016485=protein processing, 0007415=defasciculation of motor neuron axon, 0007411=axon guidance" 0016020=membrane "Tlr-1, piranha, tld-related-1, tolloid-related 1, tlr-1, CT21251, tlr1, tolloid-related, Tolloid-related, Tok, Tolkin, CG6863, tlr, Tlr, tldr-1, tldr1, TOK" "IPR028876=Cubilin, IPR000859=CUB domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR001506=Peptidase M12A, astacin, IPR018097=EGF-like calcium-binding, conserved site, IPR015446=Bone morphogenetic protein 1/tolloid-like protein, IPR000742=EGF-like domain, IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR001881=EGF-like calcium-binding domain" CG6863 16-Dec-15 2015_12 "ENSDARG00000037429(tll1),ENSDARG00000028053(bmp1b),ENSDARG00000055884,ENSDARG00000028071(bmp1a)" WBGene00003555(nas-39) "ENSXETG00000007493(TLL2),ENSXETG00000010536(bmp1),ENSXETG00000017032(TLL1)" "ENSMUSG00000025013(Tll2),ENSMUSG00000022098(Bmp1),ENSMUSG00000053626(Tll1)" "ENSG00000038295(TLL1),ENSG00000095587(TLL2),ENSG00000168487(BMP1)" " larval stage | third instar , embryonic stage , embryonic stage | stage >=12 , embryonic stage | stage 17 , embryonic stage | stage 10 , embryonic stage | blastoderm , embryonic stage | stage >=14 , embryonic stage | cellular blastoderm , embryonic stage | stage 10-11 , embryonic stage -- adult stage , larval stage " " morphogenetic furrow | anterior to

, amnioproctodeal invagination

, visceral mesoderm

, larval brain

, sensillum basiconicum

, embryonic/larval pharynx

, imaginal disc

, peripheral nervous system precursor cluster

, mesectoderm | vicinity of

,

dorsal , peripheral nervous system | restricted

, larval optic lobe

, central nervous system | restricted

, stomodeal invagination

, corpus allatum primordium

, larval outer optic anlage

, somatic mesoderm

, embryonic optic lobe primordium

, eye-antennal disc

, embryonic/larval proventriculus

, larval corpus allatum

" "visible,viable,fertile,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,neuroanatomy defective,developmental rate defective" "wing,embryonic/larval brain,imaginal disc,crossvein,longitudinal connective,intersegmental nerve,A1-7 ventral longitudinal muscle 1,embryonic/larval neuromuscular junction,abdominal segmental nerve,anterior crossvein,posterior crossvein,larval neuromuscular junction & abdominal dorsal acute muscle 1,larval neuromuscular junction & abdominal dorsal oblique muscle 1,larval neuromuscular junction & abdominal dorsal acute muscle 2,larval neuromuscular junction & abdominal dorsal oblique muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 1,larval neuromuscular junction & abdominal lateral transverse muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 3,larval neuromuscular junction & abdominal lateral transverse muscle 4,larval neuromuscular junction & abdominal ventral longitudinal muscle 1,larval neuromuscular junction & abdominal ventral longitudinal muscle 2,larval neuromuscular junction & abdominal ventral longitudinal muscle 3,larval neuromuscular junction & abdominal ventral longitudinal muscle 4,larval neuromuscular junction & abdominal ventral acute muscle 1,larval neuromuscular junction & abdominal ventral acute muscle 2,larval neuromuscular junction & abdominal ventral acute muscle 3,larval neuromuscular junction & abdominal ventral oblique muscle 4,larval neuromuscular junction & abdominal ventral oblique muscle 5,larval neuromuscular junction & abdominal ventral oblique muscle 6,segmental nerve,presumptive embryonic/larval central nervous system" FBgn0023489 Pph13 PvuII-PstI homology 13 http://flybase.net/reports/FBgn0023489.html FBgn0008638 protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0042803=protein homodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0007468=regulation of rhodopsin gene expression, 0042052=rhabdomere development, 0045893=positive regulation of transcription, DNA-templated, 0042051=compound eye photoreceptor development, 0006355=regulation of transcription, DNA-templated, 0042463=ocellus photoreceptor cell development" 0005634=nucleus "Mu, 60Mun1, hazy, Munster, CG2819, pph13, PPH13" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG2819 16-Dec-15 2015_12 ENSXETG00000004360(DMBX1) ENSMUSG00000005917(Otx1) " adult stage , embryonic stage | stage 17 , embryonic stage | stage >=12 " " eye

, photoreceptor cell &&of retina

, medulla

, Bolwig's organ | presumptive

, lamina

, Bolwig's organ | precursor

" "viable,visible,neurophysiology defective,lethal - all die before end of pupal stage,some die during pupal stage" "retina,rhabdomere,subrhabdomeral cisterna,rhabdomere of eye photoreceptor cell" FBgn0035947 Srp68 Signal recognition particle protein 68 http://flybase.net/reports/FBgn0035947.html protein_coding_gene "0005047=signal recognition particle binding, 0003729=mRNA binding, 0008312=7S RNA binding, 0030942=endoplasmic reticulum signal peptide binding" 0006614=SRP-dependent cotranslational protein targeting to membrane "0005786=signal recognition particle, endoplasmic reticulum targeting" "Srp68, CG5064" IPR026258=Signal recognition particle subunit SRP68 CG5064 16-Dec-15 2015_12 ENSDARG00000020820(srp68) YPL243W(SRP68) WBGene00010097(F55C5.8) ENSXETG00000012631(SRP68) ENSMUSG00000020780(Srp68) ENSG00000167881(SRP68) lethal "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0035600 Cyt-c1 Cytochrome c1 http://flybase.net/reports/FBgn0035600.html FBgn0027754 protein_coding_gene "0045153=electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity, 0020037=heme binding" "0006122=mitochondrial electron transport, ubiquinol to cytochrome c, 0006119=oxidative phosphorylation" "0005750=mitochondrial respiratory chain complex III, 0005811=lipid particle, 0005739=mitochondrion" "CY1, Ubiquinol-cytochrome c reductase Cytochrome C1, heme protein, anon-EST:Posey141, Ubiquinol-cytochrome c oxidoreductase Cytochrome C1, Ubiquinol-cytochrome c reductase Cytochrome c1, heme protein, Cytochrome c1, heme protein, mitochondrial, CG4769" "IPR021157=Cytochrome c1, transmembrane anchor, C-terminal, IPR002326=Cytochrome c1, IPR009056=Cytochrome c-like domain" CG4769 16-Dec-15 2015_12 ENSDARG00000038075(cyc1) YOR065W(CYT1) WBGene00000869(cyc-1) ENSMUSG00000022551(Cyc1) ENSG00000179091(CYC1) "developmental rate defective,RU486 conditional,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,adult heart,RU486 conditional" FBgn0028425 JhI-21 JhI-21 http://flybase.net/reports/FBgn0028425.html FBgn0032403 protein_coding_gene "0015179=L-amino acid transmembrane transporter activity, 0015171=amino acid transmembrane transporter activity" "0003333=amino acid transmembrane transport, 0060356=leucine import, 0050832=defense response to fungus" 0016020=membrane "CG12317, JHI-21, Jhl-21, unnamed" IPR002293=Amino acid/polyamine transporter I CG12317 16-Dec-15 2015_12 ENSDARG00000051887(LOC100333274) "YGR055W(MUP1),YHL036W(MUP3)" "immune response defective,partially lethal - majority die,some die during pupal stage,viable" "hemocyte,plasmatocyte,crystal cell" FBgn0033450 Lsm11 Lsm11 http://flybase.net/reports/FBgn0033450.html protein_coding_gene 0005515=protein binding "0000381=regulation of alternative mRNA splicing, via spliceosome, 0006398=histone mRNA 3'-end processing" "0035363=histone locus body, 0016604=nuclear body, 0005634=nucleus, 0071204=histone pre-mRNA 3'end processing complex, 0071254=cytoplasmic U snRNP body, 0005683=U7 snRNP" "CG12924, dLsm11, LSM11" "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type" CG12924 16-Dec-15 2015_12 ENSDARG00000053025(lsm11) ENSXETG00000001499(LSM11) ENSMUSG00000044847(Lsm11) ENSG00000155858(LSM11) "fertile,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,recessive" embryonic/larval somatic muscle FBgn0052107 CG32107 http://flybase.net/reports/FBgn0052107.html protein_coding_gene CG32107 16-Dec-15 2015_12 viable FBgn0002022 Catsup Catecholamines up http://flybase.net/reports/FBgn0002022.html "FBgn0022172, FBgn0032743" protein_coding_gene "0030234=enzyme regulator activity, 0046873=metal ion transmembrane transporter activity" "0055085=transmembrane transport, 0030001=metal ion transport, 2000274=regulation of epithelial cell migration, open tracheal system, 0007298=border follicle cell migration, 0042069=regulation of catecholamine metabolic process, 0007300=ovarian nurse cell to oocyte transport" "0005887=integral component of plasma membrane, 0097038=perinuclear endoplasmic reticulum, 0030424=axon, 0016020=membrane, 0043025=neuronal cell body, 0045202=synapse, 0008021=synaptic vesicle, 0005622=intracellular" "l(2)k05402, l(2)37Bc, l(2)E13, Catecholamines up, catsup, cg10449, fs(2)ltoQT50, dCATSUP, l(2)k05424, CG10449, Bc" IPR003689=Zinc/iron permease CG10449 16-Dec-15 2015_12 ENSDARG00000036388(slc39a7) WBGene00006494(hke-4.2) ENSXETG00000020367(SLC39A7) ENSMUSG00000024327(Slc39a7) "ENSG00000112473(SLC39A7),ENSG00000206288,ENSG00000206217" "lethal,lethal - all die during first instar larval stage,visible,recessive,somatic clone,wild-type,female sterile,heat sensitive,female fertile,melanotic mass phenotype,dominant,hyperactive,grooming behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable,chemical resistant,cold sensitive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,body color defective,lethal - all die during larval stage,male,female" "border follicle cell,somatic clone,wing margin,wing blade,crystal cell,melanotic mass,egg,germline clone,dorsal appendage,embryonic/larval dorsal trunk,embryonic/larval tracheal system,adult cuticle,eye,macrochaeta,embryonic/larval salivary gland,pupal cuticle,adult cuticle & adult abdomen,hemolymph,epidermis,adult cuticle & abdomen,macrochaeta & adult abdomen,tergite,adult thorax,wing" FBgn0051165 tRNA:CR31165 transfer RNA:CR31165 http://flybase.net/reports/FBgn0051165.html "FBgn0011968, FBgn0011969, FBgn0011972, FBgn0060059" tRNA_gene "0033446=AGC codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:ser2b, tRNA[Ser][[2b]], transfer RNA:ser, tRNA:ser2b, tRNA:S, tRNA:ser, tRNA:ser2b:94A, AE002708.trna26-SerGCT, transfer RNA:ser2b:94A, CR31165, tRNA:S:GCT:AE002708-a, tRNA:S2b, tRNA[[Ser]], tRNA:S2b:94A, chr3R.trna32-SerGCT" CR31165 16-Dec-15 2015_12 FBgn0263248 CG43391 http://flybase.net/reports/FBgn0263248.html protein_coding_gene CG43391 16-Dec-15 2015_12 FBgn0004749 l(3)89Bb lethal (3) 89Bb http://flybase.net/reports/FBgn0004749.html gene 16-Dec-15 2015_12 lethal FBgn0038749 Xport exit protein of rhodopsin and TRP http://flybase.net/reports/FBgn0038749.html protein_coding_gene "0016063=rhodopsin biosynthetic process, 0071482=cellular response to light stimulus, 0072321=chaperone-mediated protein transport, 0001895=retina homeostasis, 0090314=positive regulation of protein targeting to membrane, 0007603=phototransduction, visible light" 0097038=perinuclear endoplasmic reticulum "xport, CG4468" CG4468 16-Dec-15 2015_12 "neurophysiology defective,viable" "rhabdomere of eye photoreceptor cell,conditional,endoplasmic reticulum,Golgi apparatus" FBgn0052193 CG32193 http://flybase.net/reports/FBgn0052193.html protein_coding_gene 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000856 fs(1)M49 female sterile (1) M49 http://flybase.net/reports/FBgn0000856.html gene 16-Dec-15 2015_12 female sterile FBgn0022961 tardiness tardiness http://flybase.net/reports/FBgn0022961.html gene t 16-Dec-15 2015_12 FBgn0001074 fs(4)34 female sterile (4) 34 http://flybase.net/reports/FBgn0001074.html gene 16-Dec-15 2015_12 female sterile FBgn0031908 CG5177 http://flybase.net/reports/FBgn0031908.html protein_coding_gene 0004805=trehalose-phosphatase activity 0005992=trehalose biosynthetic process 0005576=extracellular region "trehalose-phosphatase, 21430192, 28603684" "IPR023214=HAD-like domain, IPR006379=HAD-superfamily hydrolase, subfamily IIB, IPR003337=Trehalose-phosphatase" CG5177 16-Dec-15 2015_12 viable FBgn0044468 EP2315 EP2315 http://flybase.net/reports/FBgn0044468.html gene unnamed 16-Dec-15 2015_12 anterior fascicle & synapse | supernumerary FBgn0085705 CG41579 http://flybase.net/reports/FBgn0085705.html FBan0041579 protein_coding_gene 16-Dec-15 2015_12 FBgn0036948 CG7298 http://flybase.net/reports/FBgn0036948.html FBgn0026283 protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" 0006030=chitin metabolic process 0005576=extracellular region anon-EST:ParkEST398 IPR002557=Chitin binding domain CG7298 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0034729 CG10344 http://flybase.net/reports/FBgn0034729.html protein_coding_gene "0019706=protein-cysteine S-palmitoyltransferase activity, 0008270=zinc ion binding" 0018345=protein palmitoylation 0005783=endoplasmic reticulum "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG10344 16-Dec-15 2015_12 ENSDARG00000036364(zdhhc24) YOL003C(PFA4) WBGene00008606(dhhc-1) ENSXETG00000011428(ZDHHC24) ENSMUSG00000006463(Zdhhc24) ENSG00000174165(ZDHHC24) "viable,visible" mesothoracic tergum FBgn0040164 l(1)G0422 lethal (1) G0422 http://flybase.net/reports/FBgn0040164.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0058264 CG40264 http://flybase.net/reports/FBgn0058264.html protein_coding_gene 16-Dec-15 2015_12 FBgn0034507 CG11192 http://flybase.net/reports/FBgn0034507.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP82 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG11192 16-Dec-15 2015_12 ENSMUSG00000032091(Tmprss4) "ENSG00000137648(TMPRSS4),ENSG00000166682(TMPRSS5),ENSG00000105707(HPN)" viable FBgn0265467 CR44360 http://flybase.net/reports/FBgn0265467.html non_protein_coding_gene CR44360 16-Dec-15 2015_12 FBgn0010438 mtSSB mitochondrial single stranded DNA-binding protein http://flybase.net/reports/FBgn0010438.html protein_coding_gene 0003697=single-stranded DNA binding "0000002=mitochondrial genome maintenance, 0006260=DNA replication" "0005739=mitochondrion, 0000262=mitochondrial chromosome" "mitochondrial single-stranded DNA-binding, mitochondrial single strand binding protein, DmmtSSB, lopo, 0046/13, low power, SSB_DROME, c3a, CG4337, mitochondrial single-stranded DNA-binding protein, SSB" "IPR011344=Single-stranded DNA-binding protein, IPR012340=Nucleic acid-binding, OB-fold, IPR000424=Primosome PriB/single-strand DNA-binding" CG4337 16-Dec-15 2015_12 ENSDARG00000039350(zgc:110325) WBGene00019800(mtss-1) ENSXETG00000020197(SSBP1) ENSMUSG00000029911(Ssbp1) ENSG00000106028(SSBP1) " embryonic stage -- adult stage , embryonic stage , embryonic stage | early , oogenesis stage && adult stage | female " " posterior midgut proper primordium

,

ubiquitous , ovary

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, anterior midgut proper primordium

" "viable,fertile,lethal,recessive,cell growth defective,wild-type,visible" "larval midgut & mitochondrion,trichogen cell" DRSC17005 EK 0.896460492 0.067973094 2.029190659 0.144965595 1.784392763 -0.427941742 FBgn0034853 Ice1 Interacts with the C terminus of ELL 1 http://flybase.net/reports/FBgn0034853.html protein_coding_gene 0003682=chromatin binding "0022008=neurogenesis, 0007052=mitotic spindle organization, 0042795=snRNA transcription from RNA polymerase II promoter" 0032783=ELL-EAF complex "dICE1, CG13550, ICE1" CG13550 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0051465 CG31465 http://flybase.net/reports/FBgn0051465.html FBgn0038913 protein_coding_gene CG6670 CG31465 16-Dec-15 2015_12 "viable,fertile" FBgn0004799 fs(2)ltoHE41 female sterile (2) ltoHE41 http://flybase.net/reports/FBgn0004799.html gene "0007297=ovarian follicle cell migration, 0048477=oogenesis" 16-Dec-15 2015_12 female sterile FBgn0029666 CG10803 http://flybase.net/reports/FBgn0029666.html protein_coding_gene 0003723=RNA binding IPR008858=TROVE domain CG10803 16-Dec-15 2015_12 ENSXETG00000017224(TROVE2) ENSMUSG00000018199(Trove2) ENSG00000116747(TROVE2) viable FBgn0001746 l(1)HM18 lethal (1) HM18 http://flybase.net/reports/FBgn0001746.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female fertile" FBgn0053333 CG33333 http://flybase.net/reports/FBgn0053333.html protein_coding_gene CG33333 16-Dec-15 2015_12 viable FBgn0266702 CR45192 http://flybase.net/reports/FBgn0266702.html non_protein_coding_gene CR45192 16-Dec-15 2015_12 FBgn0000705 fltK flight defective K http://flybase.net/reports/FBgn0000705.html gene 16-Dec-15 2015_12 "flightless,jumping defective,partially" FBgn0264478 CG43886 http://flybase.net/reports/FBgn0264478.html protein_coding_gene lincRNA.469 CG43886 16-Dec-15 2015_12 FBgn0260621 2L2798 http://flybase.net/reports/FBgn0260621.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0041172 ade4 ade4 http://flybase.net/reports/FBgn0041172.html gene 16-Dec-15 2015_12 "eye color defective,recessive,auxotroph" pigment cell FBgn0264350 CR43806 http://flybase.net/reports/FBgn0264350.html non_protein_coding_gene CR43806 16-Dec-15 2015_12 FBgn0065357 l(2)SH1756 lethal (2) SH1756 http://flybase.net/reports/FBgn0065357.html gene l(2)SH2 1756 16-Dec-15 2015_12 "lethal,recessive" FBgn0065328 l(2)SH1894 lethal (2) SH1894 http://flybase.net/reports/FBgn0065328.html gene l(2)SH2 1894 16-Dec-15 2015_12 "lethal,recessive" FBgn0063386 snoRNA:Me18S-A28a http://flybase.net/reports/FBgn0063386.html snoRNA_gene "snoRNA:U27:54Ec, CR32902, U27snoRNA, Me18S-A28a(U27)" CR32902 16-Dec-15 2015_12 FBgn0262075 JC13 http://flybase.net/reports/FBgn0262075.html gene 0072347=response to anesthetic 16-Dec-15 2015_12 "chemical sensitive,recessive" FBgn0036708 CG13725 http://flybase.net/reports/FBgn0036708.html protein_coding_gene CG13725 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum FBgn0002909 mus312 mutagen-sensitive 312 http://flybase.net/reports/FBgn0002909.html FBgn0035764 protein_coding_gene "0005515=protein binding, 0017108=5'-flap endonuclease activity" "0045132=meiotic chromosome segregation, 0006260=DNA replication, 0000712=resolution of meiotic recombination intermediates, 0007131=reciprocal meiotic recombination, 0006281=DNA repair, 0000715=nucleotide-excision repair, DNA damage recognition, 0008283=cell proliferation, 0035825=reciprocal DNA recombination, 0007095=mitotic G2 DNA damage checkpoint" "0033557=Slx1-Slx4 complex, 0043234=protein complex" "mus(3)312, MUS312, CG8601" IPR018574=Structure-specific endonuclease subunit Slx4 CG8601 16-Dec-15 2015_12 "radiation sensitive,chemical sensitive,recessive,meiotic cell cycle defective,viable" presumptive oocyte DRSC11008 K 0.007082853 0.322142703 0.156995852 -0.08572813 2.086020639 0.284607949 FBgn0004785 anon-g anon guanine-rich sequence http://flybase.net/reports/FBgn0004785.html repeat_region 16-Dec-15 2015_12 FBgn0061151 l(2)K152 lethal (2) K152 http://flybase.net/reports/FBgn0061151.html gene K152 16-Dec-15 2015_12 "lethal,recessive" FBgn0028899 CG31817 http://flybase.net/reports/FBgn0028899.html "FBgn0051817, FBgn0066376, FBgn0066377" protein_coding_gene "BG:DS02740.18, anon-WO03042407.99, anon-WO03042407.98, DS02740.18" CG31817 16-Dec-15 2015_12 viable DRSC01537 IEK -1.706612885 0.726853781 -1.925911061 0.065487358 2.558978342 0.492616223 FBgn0025502 l(3)73Al lethal (3) 73Al http://flybase.net/reports/FBgn0025502.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0011020 Sas-4 Spindle assembly abnormal 4 ortholog (C. elegans) http://flybase.net/reports/FBgn0011020.html FBgn0037480 protein_coding_gene "0040011=locomotion, 0008356=asymmetric cell division, 0007140=male meiosis, 0007052=mitotic spindle organization, 0042384=cilium assembly, 0051299=centrosome separation, 0046785=microtubule polymerization, 0007099=centriole replication, 0051298=centrosome duplication, 0051297=centrosome organization, 0035186=syncytial blastoderm mitotic cell cycle" "0000242=pericentriolar material, 0045298=tubulin complex, 0005814=centriole" "sas4, lethal (3) s2214, l(3)s2214, CG10061, DSas4, d-SAS-4, Sas-4, SAS-4, D-sas4, Dsas-4, Sas4, SAS4, l(3)S2214, DSAS-4, Dsas4, D-Sas4, sas-4, Drosophila Sas-4, dsas-4, DSas-4, CPAP" "IPR026581=T-complex protein 10 family, IPR009852=T-complex protein 10, C-terminal domain" CG10061 16-Dec-15 2015_12 ENSMUSG00000064128(Cenpj) ENSG00000151849(CENPJ) "mitotic cell cycle defective,cytokinesis defective,uncoordinated,mating defective,male sterile,lethal,recessive,cell polarity defective,somatic clone,cell cycle defective,meiotic cell cycle defective,developmental rate defective,some die during immature adult stage,viable,visible" "male germline stem cell,spermatid axoneme,aster, with Sas-4s2214,embryonic/larval brain,spindle,neuroblast,centriole,centrosome,cilium,flagellum (obsolete ),spermatid,sensory neuron,primary spermatocyte,aster, with Sas-4ëÓT.TAvicGFP,centriole | ectopicmat.ë±Tub67C.THsimVP16,trichogen cell,supernumerary" FBgn0034451 TBCB tubulin-binding cofactor B http://flybase.net/reports/FBgn0034451.html protein_coding_gene "0007309=oocyte axis specification, 0031122=cytoplasmic microtubule organization, 0035089=establishment of apical/basal cell polarity" "0005813=centrosome, 0072686=mitotic spindle, 0005737=cytoplasm, 0005634=nucleus, 0005856=cytoskeleton, 0005938=cell cortex" "CG11242, dTBCB" "IPR000626=Ubiquitin domain, IPR029071=Ubiquitin-related domain, IPR000938=CAP Gly-rich domain" CG11242 16-Dec-15 2015_12 "ENSDARG00000068404(tbcb),ENSDARG00000068112" YNL148C(ALF1) WBGene00009987(F53F4.3) ENSXETG00000019070(TBCB) ENSMUSG00000006095(Tbcb) ENSG00000105254(TBCB) "cell cycle defective,recessive,cell polarity defective,germline clone,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile,partially lethal - majority live,visible" "oocyte,germline clone,nurse cell,somatic clone,follicle cell,neuroblast,wing" FBgn0031097 obst-A obstructor-A http://flybase.net/reports/FBgn0031097.html protein_coding_gene "0008061=chitin binding, 0016490=structural constituent of peritrophic membrane" "0040003=chitin-based cuticle development, 0010716=negative regulation of extracellular matrix disassembly, 0006030=chitin metabolic process" 0005615=extracellular space "Obstructor-A, CG17052, obstructor, obst" IPR002557=Chitin binding domain CG17052 16-Dec-15 2015_12 "lethal,small body,lethal - all die before end of larval stage,recessive,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval tracheal system,embryonic/first instar larval cuticle,cuticle,taenidial fold,trichogen cell" FBgn0031016 kek5 kekkon5 http://flybase.net/reports/FBgn0031016.html protein_coding_gene "0030510=regulation of BMP signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway" "0005887=integral component of plasma membrane, 0005886=plasma membrane" "CG12199, kekkon-like, CT10486, Kek5, Kekkon5" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003591=Leucine-rich repeat, typical subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR001611=Leucine-rich repeat" CG12199 16-Dec-15 2015_12 "ENSDARG00000007856,ENSDARG00000055578(rtn4rl1),ENSDARG00000052012(rtn4rl2a),ENSDARG00000037495(rtn4rl2b),ENSDARG00000025697(rtn4r)" WBGene00021353(Y37E3.13) "ENSXETG00000024115(LRIT3),ENSXETG00000005631(LRIT2)" "ENSMUSG00000035653(Lrfn5),ENSMUSG00000040490(Lrfn2),ENSMUSG00000030600(Lrfn1),ENSMUSG00000036957(Lrfn3),ENSMUSG00000045045(Lrfn4)" "ENSG00000173621(LRFN4),ENSG00000156564(LRFN2),ENSG00000126243(LRFN3),ENSG00000165379(LRFN5),ENSG00000128011(LRFN1)" "viable,fertile,visible,recessive,short lived,size defective" "crossvein,wing blade,anterior crossvein,wing,posterior crossvein,scutellar bristle,supernumerary,mesothoracic tergum" FBgn0031467 Cpr23B Cuticular protein 23B http://flybase.net/reports/FBgn0031467.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG2973, DmelCpr23B" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG2973 16-Dec-15 2015_12 viable DRSC00555 E -0.803928344 1.448963303 3.57083133 -0.411181556 0.487095223 0.551315949 FBgn0027108 Inx2 Innexin 2 http://flybase.net/reports/FBgn0027108.html "FBgn0026672, FBgn0026693, FBgn0026703, FBgn0026707, FBgn0027220, FBgn0027325, FBgn0028356, FBgn0029062" protein_coding_gene 0005243=gap junction channel activity "0042048=olfactory behavior, 0007440=foregut morphogenesis, 0010496=intercellular transport, 0007154=cell communication, 0016331=morphogenesis of embryonic epithelium, 0030727=germarium-derived female germ-line cyst formation, 0007293=germarium-derived egg chamber formation" "0016324=apical plasma membrane, 0005921=gap junction, 0016327=apicolateral plasma membrane" "Dm-inx, Dm-inx2, Innexin2, Ix2, inx-2, l(1)G0043, FBpp0291074, l(1)G0157, innexin2, l(1)G0036, l(1)G0364, l(1)G0035, INX-2, l(1)G0059, pas related protein 33, D-inx-2, CG4590, Inx2, Innexin, Innexin-2, prp33, innexin 2, l(1)G0118, kropf, l(1)G0317, inx2" IPR000990=Innexin CG4590 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" "lethal,recessive,female,lethal - all die during embryonic stage,viable,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,visual behavior defective,female sterile,feeding behavior defective,small body,increased cell death,rescuable maternal effect,cell shape defective,partially lethal - majority die,smell perception defective,partially,lethal - all die before end of pupal stage,some die during pupal stage,visible,lethal - all die during first instar larval stage" "ovary,germarium,female germline cell,synaptic vesicleMz709,photoreceptor cell,embryonic hindgut,embryonic Malpighian tubule,presumptive embryonic salivary gland,presumptive embryonic/larval tracheal system,embryonic foregut,embryonic/first instar larval cuticle,rescuable maternal effect,embryonic head,embryonic segment,embryonic epidermis,embryonic/larval proventriculus,proventriculus primordium,trichogen cell,egg chamber" FBgn0262739 AGO1 Argonaute-1 http://flybase.net/reports/FBgn0262739.html "FBgn0026611, FBgn0010586, FBgn0022056, FBgn0022275, FBgn0063793, FBgn0086551" protein_coding_gene "0019899=enzyme binding, 0035198=miRNA binding, 0003743=translation initiation factor activity, 0005515=protein binding" "0007416=synapse assembly, 0007367=segment polarity determination, 0030422=production of siRNA involved in RNA interference, 0030423=targeting of mRNA for destruction involved in RNA interference, 0035196=production of miRNAs involved in gene silencing by miRNA, 0006402=mRNA catabolic process, 0017148=negative regulation of translation, 0090328=regulation of olfactory learning, 0046959=habituation, 0035195=gene silencing by miRNA, 0030727=germarium-derived female germ-line cyst formation, 0016246=RNA interference, 0035279=mRNA cleavage involved in gene silencing by miRNA, 0036099=female germ-line stem cell maintenance, 0007294=germarium-derived oocyte fate determination, 0006342=chromatin silencing" "0005850=eukaryotic translation initiation factor 2 complex, 0005737=cytoplasm, 0016442=RISC complex, 0005634=nucleus, 0048471=perinuclear region of cytoplasm, 0030529=ribonucleoprotein complex" "l(2)4845, argonaute 1, argonaute-1, l(2)k08121, Ago, Argonaute 1, anon-WO0257455.29, Argonaute protein 1, l(2)04845, l(2)k00208, CG6671, Dm Ago1, Ago-1, MRE20, mRNA-like ncRNA in embryogenesis 20, dAGO1, argonaute1, DmAgo1, Argonaute, dAgo1, AGO-1, ARGONAUTE-1, ago1-1, ago1, Argonaute1, Agp1, Ago1" "IPR012337=Ribonuclease H-like domain, IPR003100=PAZ domain, IPR003165=Piwi domain, IPR014811=Argonaute, linker 1 domain" CG6671 16-Dec-15 2015_12 "ENSDARG00000059882,ENSDARG00000059888(LOC567622),ENSDARG00000063079(eif2c3),ENSDARG00000015279,ENSDARG00000061268(LOC570630)" "WBGene00000105(alg-1),WBGene00000106(alg-2)" "ENSXETG00000023755(eif2c2),ENSXETG00000004364(EIF2C1),ENSXETG00000027042(EIF2C3)" "ENSMUSG00000041530(Eif2c1),ENSMUSG00000028842(Eif2c3),ENSMUSG00000036698" "ENSG00000092847(EIF2C1),ENSG00000126070(EIF2C3),ENSG00000134698(EIF2C4),ENSG00000123908(EIF2C2)" DRSC05912 I -2.003046054 2.415274581 1.091121184 0.605080755 1.17027256 1.378684056 FBgn0039449 CG6425 http://flybase.net/reports/FBgn0039449.html protein_coding_gene CG6425 16-Dec-15 2015_12 "viable,fertile" FBgn0025736 puri puri http://flybase.net/reports/FBgn0025736.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "wing,somatic clone" FBgn0036398 upSET upSET http://flybase.net/reports/FBgn0036398.html protein_coding_gene "0001047=core promoter binding, 0042054=histone methyltransferase activity, 0008270=zinc ion binding" "0048477=oogenesis, 0006343=establishment of chromatin silencing, 0070868=heterochromatin organization involved in chromatin silencing, 0016573=histone acetylation" "0005700=polytene chromosome, 0035327=transcriptionally active chromatin, 0005634=nucleus" CG9007 "IPR001965=Zinc finger, PHD-type, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR001214=SET domain, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG9007 16-Dec-15 2015_12 ENSDARG00000007523 "ENSMUSG00000029004,ENSMUSG00000034269(Setd5)" "ENSG00000005483(MLL5),ENSG00000168137(SETD5)" "viable,female sterile,recessive" "egg chamber,nurse cell,heart primordium" FBgn0264642 denuded denuded http://flybase.net/reports/FBgn0264642.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0019675 mor(1)4 mortality gene (1)4 http://flybase.net/reports/FBgn0019675.html gene 16-Dec-15 2015_12 short lived FBgn0004506 fs(1)K4 female sterile (1) K4 http://flybase.net/reports/FBgn0004506.html gene 16-Dec-15 2015_12 "female sterile germline-dependent,recessive" egg FBgn0266633 CR45140 http://flybase.net/reports/FBgn0266633.html non_protein_coding_gene CR45140 16-Dec-15 2015_12 FBgn0050234 tRNA:CR30234 transfer RNA:CR30234 http://flybase.net/reports/FBgn0050234.html FBgn0060169 tRNA_gene 0033417=CUU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002787.trna13-LeuAAG, chr2R.trna71-LeuAAG, CR30234, tRNA:L:AAG:AE002787-a" CR30234 16-Dec-15 2015_12 FBgn0067061 P270 P270 http://flybase.net/reports/FBgn0067061.html gene 16-Dec-15 2015_12 neurophysiology defective FBgn0033191 CG1598 http://flybase.net/reports/FBgn0033191.html "FBgn0043826, FBgn0064939" protein_coding_gene "0005524=ATP binding, 0015446=arsenite-transmembrane transporting ATPase activity" "BEST:GH10483, gh10483, BcDNA:GM18141" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR016300=Arsenical pump ATPase, ArsA/GET3, IPR027542=Arsenical pump ATPase, ArsA/GET3, eukaryotic, IPR025723=Anion-transporting ATPase-like domain" CG1598 16-Dec-15 2015_12 ENSDARG00000018190(asna1) YDL100C(GET3) WBGene00014025(asna-1) ENSXETG00000004767(ASNA1) ENSMUSG00000052456(Asna1) ENSG00000198356(ASNA1) viable DRSC06598 K -0.435135758 -0.093731261 -0.713471094 0.138290512 -1.530166423 -0.33084254 FBgn0035245 GC gamma-glutamyl carboxylase http://flybase.net/reports/FBgn0035245.html protein_coding_gene 0008488=gamma-glutamyl carboxylase activity "0017187=peptidyl-glutamic acid carboxylation, 0018214=protein carboxylation" "DgammaC, dGC, gammaC, gamma-glutamyl carboxylase, CG13927, dgammaC, gamma-glutamyl-carboxylase" "IPR011020=HTTM, IPR007782=Vitamin K-dependent gamma-carboxylase" CG13927 16-Dec-15 2015_12 ENSXETG00000001264(GGCX) ENSMUSG00000053460(Ggcx) ENSG00000115486(GGCX) "viable,fertile" FBgn0051704 CG31704 http://flybase.net/reports/FBgn0051704.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0032504=multicellular organism reproduction, 0006508=proteolysis" 0005615=extracellular space IPR002350=Kazal domain CG31704 16-Dec-15 2015_12 "ENSDARG00000071806,ENSDARG00000071808(zgc:158852)" ENSMUSG00000024503(Spink3) ENSG00000128040(SPINK2) "viable,lethal - all die before end of pupal stage,some die during pupal stage" DRSC22118 I -0.083424612 -2.815756413 1.002525336 0.0670848 -0.51600523 -0.140750912 FBgn0005178 l(2)S1 lethal of Seto http://flybase.net/reports/FBgn0005178.html gene 16-Dec-15 2015_12 lethal puparium FBgn0086203 S(ls)5 http://flybase.net/reports/FBgn0086203.html gene 16-Dec-15 2015_12 FBgn0024314 Plap Phospholipase A2 activator protein http://flybase.net/reports/FBgn0024314.html FBgn0031316 protein_coding_gene 0016005=phospholipase A2 activator activity 0045169=fusome "dPLAP, UFD3, plap, dmPLAP, CG5105" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR015155=PLAA family ubiquitin binding, PFU, IPR019775=WD40 repeat, conserved site, IPR013535=PUL domain" CG5105 16-Dec-15 2015_12 ENSDARG00000042728(plaa) YKL213C(DOA1) WBGene00007333(ufd-3) ENSXETG00000009385(PLAA) ENSMUSG00000028577(Plaa) ENSG00000137055(PLAA) "viable,fertile" FBgn0065406 l(2)SH1580 lethal (2) SH1580 http://flybase.net/reports/FBgn0065406.html gene l(2)SH2 1580 16-Dec-15 2015_12 "lethal,recessive" FBgn0265073 CR44184 http://flybase.net/reports/FBgn0265073.html non_protein_coding_gene CR44184 16-Dec-15 2015_12 FBgn0086912 mbm mushroom body miniature http://flybase.net/reports/FBgn0086912.html "FBgn0002687, FBgn0031242" protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "0007632=visual behavior, 0016319=mushroom body development, 0007628=adult walking behavior, 0007612=learning, 0008355=olfactory learning" "MB miniature, mushroom bodies small, mus, CG11604, mushroom-body-miniature, mushroom bodies miniature" "IPR001878=Zinc finger, CCHC-type" CG11604 16-Dec-15 2015_12 FBgn0051071 tRNA:CR31071 transfer RNA:CR31071 http://flybase.net/reports/FBgn0051071.html FBgn0060098 tRNA_gene 0033427=CAA codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "AE002708.trna35-GlnTTG, tRNA:Q:TTG:AE002708-b, chr3R.trna41-GlnTTG, CR31071" CR31071 16-Dec-15 2015_12 FBgn0005120 l(1)m lethal (1) malignant http://flybase.net/reports/FBgn0005120.html gene l-mal 16-Dec-15 2015_12 "lethal,melanotic mass phenotype" melanotic mass FBgn0036195 CG6053 http://flybase.net/reports/FBgn0036195.html protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled" "0007018=microtubule-based movement, 0007605=sensory perception of sound" "0005875=microtubule associated complex, 0005868=cytoplasmic dynein complex" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site" CG6053 16-Dec-15 2015_12 ENSDARG00000004541(zgc:162235) WBGene00016165(C27F2.1) ENSXETG00000012829(DNAI2) ENSMUSG00000034706(Dnaic2) ENSG00000171595(DNAI2) "auditory perception defective,neurophysiology defective,viable" FBgn0085219 CG34190 http://flybase.net/reports/FBgn0085219.html protein_coding_gene CG34190 16-Dec-15 2015_12 FBgn0264566 CG43938 http://flybase.net/reports/FBgn0264566.html protein_coding_gene CG43938 16-Dec-15 2015_12 FBgn0040767 CG13233 http://flybase.net/reports/FBgn0040767.html protein_coding_gene 16-Dec-15 2015_12 FBgn0011693 Pdh Photoreceptor dehydrogenase http://flybase.net/reports/FBgn0011693.html protein_coding_gene "0004022=alcohol dehydrogenase (NAD) activity, 0004745=retinol dehydrogenase activity" "0042574=retinal metabolic process, 0042572=retinol metabolic process, 0006909=phagocytosis, 0055114=oxidation-reduction process" "pdh, pigment cell dehydrogenase reductase, pcdr, CG4899" "IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002424=Alcohol dehydrogenase, insect-type" CG4899 16-Dec-15 2015_12 "ENSDARG00000026236(zgc:56585),ENSDARG00000012016(LOC565975)" ENSXETG00000016904(hpgd) ENSMUSG00000031613(Hpgd) ENSG00000164120(HPGD) "viable,fertile,neurophysiology defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" rhabdomere FBgn0033042 Tsp42A Tetraspanin 42A http://flybase.net/reports/FBgn0033042.html protein_coding_gene 0016021=integral component of membrane "Dm.Tsp42A, CG14468" "IPR008952=Tetraspanin, EC2 domain" CG14468 16-Dec-15 2015_12 viable FBgn0032210 CYLD cylindromatosis ortholog (H. sapiens) http://flybase.net/reports/FBgn0032210.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 0003700=sequence-specific DNA binding transcription factor activity" "0042742=defense response to bacterium, 0008340=determination of adult lifespan, 0031098=stress-activated protein kinase signaling cascade, 0006979=response to oxidative stress, 0045088=regulation of innate immune response, 0016579=protein deubiquitination, 0055090=acylglycerol homeostasis, 0006511=ubiquitin-dependent protein catabolic process" 0005634=nucleus "Q8IPC5, cyld, CG5603, Cyld, cylindromatosis, CYLD, dCYLD" "IPR028889=Ubiquitin specific protease domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR000938=CAP Gly-rich domain" CG5603 16-Dec-15 2015_12 ENSDARG00000060058(cylda) WBGene00009594(cyld-1) ENSXETG00000000105(CYLD) ENSMUSG00000036712(Cyld) ENSG00000083799(CYLD) "viable,fertile,short lived,recessive,oxidative stress response defective,visible,immune response defective,locomotor behavior defective" "scutellum,adult fat body,lipid particle,lipid particle | supernumerary" FBgn0263624 CR43633 http://flybase.net/reports/FBgn0263624.html non_protein_coding_gene CR43633 16-Dec-15 2015_12 FBgn0085305 CG34276 http://flybase.net/reports/FBgn0085305.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity CG5470 IPR002223=Pancreatic trypsin inhibitor Kunitz domain CG34276 16-Dec-15 2015_12 viable FBgn0034937 fzr2 fizzy-related 2 http://flybase.net/reports/FBgn0034937.html protein_coding_gene "0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation, 0007140=male meiosis, 0010458=exit from mitosis" "FZR2, CG16783" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site" CG16783 16-Dec-15 2015_12 YGL003C(CDH1) " adult stage , pupal stage&&adult stage " " spermatocyte

, testis

" viable FBgn0267203 CR45643 http://flybase.net/reports/FBgn0267203.html non_protein_coding_gene CR45643 16-Dec-15 2015_12 FBgn0265743 CR44550 http://flybase.net/reports/FBgn0265743.html non_protein_coding_gene CR44550 16-Dec-15 2015_12 FBgn0024760 EC7 EC7 http://flybase.net/reports/FBgn0024760.html gene 16-Dec-15 2015_12 enhancer of variegation FBgn0030701 CG16952 http://flybase.net/reports/FBgn0030701.html protein_coding_gene "IPR011705=BTB/Kelch-associated, IPR000210=BTB/POZ domain, IPR011333=POZ domain" CG16952 16-Dec-15 2015_12 ENSDARG00000003069(btbd7) WBGene00016540(C39F7.5) ENSXETG00000010307(BTBD7) ENSMUSG00000041702(Btbd7) ENSG00000011114(BTBD7) "viable,fertile" FBgn0264961 CR44130 http://flybase.net/reports/FBgn0264961.html non_protein_coding_gene CR44130 16-Dec-15 2015_12 FBgn0026730 aos::sty argos::sty http://flybase.net/reports/FBgn0026730.html engineered_fusion_gene argos::sty 16-Dec-15 2015_12 FBgn0010473 tutl turtle http://flybase.net/reports/FBgn0010473.html "FBgn0004699, FBgn0031593, FBgn0031594, FBgn0031595" protein_coding_gene 0098632=protein binding involved in cell-cell adhesion "0008039=synaptic target recognition, 0048814=regulation of dendrite morphogenesis, 0007422=peripheral nervous system development, 0007414=axonal defasciculation, 0030537=larval behavior, 0007411=axon guidance, 0070593=dendrite self-avoidance, 0046331=lateral inhibition, 0007638=mechanosensory behavior, 0008344=adult locomotory behavior, 0016199=axon midline choice point recognition, 0045467=R7 cell development, 0007629=flight behavior" 0005887=integral component of plasma membrane "jf4, mdcds_7441, l(2)24Df, lethal(2)24Df, CG15426, Tutl, CT35490, l(2)jf4, CT35489, CG15428, CG15427, l(2)01085, Turtle" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain" CG15427 16-Dec-15 2015_12 "ENSXETG00000008342(IGSF9B),ENSXETG00000008115(IGSF9)" ENSMUSG00000037995(Igsf9) ENSG00000085552(IGSF9) "touch sensitivity defective,neuroanatomy defective,somatic clone,partially lethal - majority live,behavior defective,recessive,flightless,lethal,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,viable,visible,lethal - all die before end of pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "dendrite & dorsal multidendritic neuron ddaE,dendrite & dorsal multidendritic neuron ddaC,dendrite & dorsal multidendritic neuron ddaEed-dp),dendrite & dorsal multidendritic neuron ddaE | somatic clone,dendrite & dorsal multidendritic neuron ddaC | somatic clone,photoreceptor cell R7,intersegmental nerve branch ISNb of A1-7,intersegmental nerve branch ISNd of A1-7,optic chiasma,lateral medial fascicle,ventral nerve cord commissure,medial longitudinal fascicle,intermediate longitudinal fascicle,lateral longitudinal fascicle,midline crossing tract,somatic clone,photoreceptor cell R8,dendrite & dorsal multidendritic neuron ddaCppk.1.9,chaeta,supernumerary,mesothoracic tergum,longitudinal connective,commissure,transverse nerve,optic lobe,neuropil" DRSC00442 I 1.685338574 0.820241912 -0.400300591 -0.139576424 -0.046393783 0.060334327 FBgn0011259 Sema-1a Sema-1a http://flybase.net/reports/FBgn0011259.html "FBgn0021877, FBgn0063028" protein_coding_gene "0030215=semaphorin receptor binding, 0008201=heparin binding, 0005515=protein binding" "0008045=motor neuron axon guidance, 0007416=synapse assembly, 0048854=brain morphogenesis, 0016199=axon midline choice point recognition, 0048813=dendrite morphogenesis, 0008039=synaptic target recognition, 2000305=semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance, 0007411=axon guidance, 0031987=locomotion involved in locomotory behavior, 0045792=negative regulation of cell size, 0001964=startle response" "0005886=plasma membrane, 0016021=integral component of membrane" "CG18405, D-Sema I, sema1a, D-Sema-I, Fasciclin-IV, Semaphorin1a, Semaphorin-1, sema, CT26404, sema-1a, D-SemaI, Dsema-I, D-semaI, BcDNA:RE36155, semaphorin 1, D-Sema 1a, Semaphorin-1a, semaphorin-1a, semaphorin I, SemaI, semaphorin1a, Sema-I, Dsema 1a, Fas-IV, Sema1a, Sema1A, semiphorin, FasIV, d-semaI, Sema 1a, Semaphorin 1a, d-sema I, sema 1a, semaphorin, Semaphorin-1A, sema-I, l(2)k13702, SEMA-1A" "IPR027231=Semaphorin, IPR016201=Plexin-like fold, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001627=Sema domain, IPR002165=Plexin repeat" CG18405 16-Dec-15 2015_12 "ENSDARG00000011533(zgc:112012),ENSDARG00000002748(sema6d),ENSDARG00000018879,ENSDARG00000061976(LOC100148883)" WBGene00004889(smp-1) "ENSXETG00000014232(SEMA3A),ENSXETG00000007320(),ENSXETG00000005431(SEMA3D),ENSXETG00000007874(sema3c),ENSXETG00000007312(Q5U4Y0_XENTR),ENSXETG00000007179(sema3f)" "ENSMUSG00000038777(Sema6c),ENSMUSG00000001227(Sema6b),ENSMUSG00000019647(Sema6a),ENSMUSG00000027200(Sema6d)" "ENSG00000167680(SEMA6B),ENSG00000092421(SEMA6A),ENSG00000137872(SEMA6D),ENSG00000143434(SEMA6C)" embryonic stage " central nervous system

, embryonic peripheral nervous system

, sense organ | lateral

, embryonic neuron

" "viable,lethal,recessive,partially lethal - majority die,neuroanatomy defective,somatic clone,cell non-autonomous,heat sensitive,neurophysiology defective,some die during pupal stage" "segmental nerve,intersegmental nerve,synapse,synapse | ectopic,abdominal ventral longitudinal muscle & synapse,transverse nerve,longitudinal connective,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina,lateral longitudinal fascicle,RP3 neuron & synapse,RP5 neuron & synapse,presumptive embryonic/larval central nervous system,axon & beta'-lobe | somatic clone,axon & alpha'-lobe | somatic clone,axon & antennal glomerulus DL1 | somatic clone | cell autonomous,dendrite & antennal glomerulus DL1 | somatic clone,dendrite & antennal glomerulus DA1 | somatic clone,dendrite & antennal glomerulus DC3 | somatic clone,axon & antennal glomerulus DA1 | somatic clone,axon & antennal glomerulus DC3 | somatic clone,axon & antennal glomerulus VM2 | somatic clone,adult olfactory receptor neuron Or33c/85e,cell non-autonomous,somatic clone,adult olfactory receptor neuron Or46a,adult olfactory receptor neuron Or42a,adult olfactory receptor neuron Or59c,axon & eye photoreceptor cell,eye photoreceptor cell & lamina,axon & lamina,axon & eye photoreceptor cell | somatic clone | cell autonomous,axon & lamina | somatic clone | somatic clone | cell autonomous,eye photoreceptor cell & lamina | somatic clone | cell autonomous,abdominal segmental nerve,adult olfactory receptor neuron Or71a,adult olfactory receptor neuron Or43a,adult olfactory receptor neuron Or83c,adult olfactory receptor neuron Or88a,adult olfactory receptor neuron Or23a,adult olfactory receptor neuron Or35a,adult olfactory receptor neuron Or67b,adult olfactory receptor neuron Or47b,eye photoreceptor cell,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,posterior commissure,anterior commissure,posterior commissure | embryonic stage,axon & eye photoreceptor cellN22-5),eye photoreceptor cell & laminaN22-5),axon & laminaN22-5),abdominal intersegmental nerve,ventral nerve cord,motor neuron,giant fiber neuron,heat sensitive,intersegmental nerve | embryonic stage,segmental nerve | embryonic stage,dendrite & antennal glomerulus | somatic cloneGH146,axon & eye photoreceptor cellGMR.PF,axon & laminaGMR.PF,eye photoreceptor cell & laminaGMR.PF,axon & medullaGMR.PF,eye photoreceptor cell & medullaGMR.PF,nerve terminal & lamina plexusGMR.PF,eye photoreceptor cell | third instar larval stage,lamina | third instar larval stage,photoreceptor cell R1 & lamina,photoreceptor cell R2 & lamina,photoreceptor cell R3 & lamina,photoreceptor cell R4 & lamina,photoreceptor cell R5 & lamina,photoreceptor cell R7 & lamina" FBgn0034396 CG15097 http://flybase.net/reports/FBgn0034396.html protein_coding_gene 0003779=actin binding Dm.CG15097 "IPR011705=BTB/Kelch-associated, IPR006652=Kelch repeat type 1, IPR011043=Galactose oxidase/kelch, beta-propeller, IPR011333=POZ domain, IPR000210=BTB/POZ domain, IPR015916=Galactose oxidase, beta-propeller, IPR017096=BTB-kelch protein" CG15097 16-Dec-15 2015_12 ENSDARG00000037324(LOC569221) ENSMUSG00000078484(Klhl17) ENSG00000187961(KLHL17) viable FBgn0259340 C839 http://flybase.net/reports/FBgn0259340.html gene 16-Dec-15 2015_12 visible "wing hair,chaeta,ectopic" FBgn0032883 CG9323 http://flybase.net/reports/FBgn0032883.html protein_coding_gene "0002151=G-quadruplex RNA binding, 0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0008026=ATP-dependent helicase activity, 0004386=helicase activity" "cg9323, 38E.15" "IPR011545=DEAD/DEAH box helicase domain, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR007502=Helicase-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011709=Domain of unknown function DUF1605" CG9323 16-Dec-15 2015_12 ENSDARG00000061922(si:dkey-119o24.1) ENSXETG00000007768(DHX36) ENSMUSG00000027770(Dhx36) ENSG00000174953(DHX36) "viable,fertile,lethal" FBgn0024929 Su(var)2-b4801 Su(var)2-b4801 http://flybase.net/reports/FBgn0024929.html gene Su-var(2)b4801 16-Dec-15 2015_12 FBgn0266449 Kr-h2 Kruppel homolog 2 http://flybase.net/reports/FBgn0266449.html "FBgn0028419, FBgn0001326, FBgn0041608" protein_coding_gene "0012505=endomembrane system, 0016021=integral component of membrane" "Kr-H2, CG9159, Kr-h, anon-26Ba, Kruppel homolog, unnamed" IPR005344=Per33/Pom33 family CG9159 16-Dec-15 2015_12 ENSDARG00000041332(tmem33) WBGene00012555(Y37D8A.17) ENSXETG00000021080(TMEM33) ENSMUSG00000037720(Tmem33) ENSG00000109133(TMEM33) FBgn0017378 l(1)HM409 lethal (1) HM409 http://flybase.net/reports/FBgn0017378.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030614 CG9072 http://flybase.net/reports/FBgn0030614.html protein_coding_gene "0051082=unfolded protein binding, 0015631=tubulin binding" 0007021=tubulin complex assembly IPR004226=Tubulin binding cofactor A CG9072 16-Dec-15 2015_12 YOR265W(RBL2) lethal FBgn0022306 l(1)L25.7 lethal (1) L25.7 http://flybase.net/reports/FBgn0022306.html gene L25.7 16-Dec-15 2015_12 "lethal,recessive" FBgn0263531 mir-4955 mir-4955 stem loop http://flybase.net/reports/FBgn0263531.html miRNA_gene "dme-mir-4955, CR43516" CR43516 16-Dec-15 2015_12 FBgn0023166 Su(mg)1-1 Suppressor of modifier of gypsy 1-1 http://flybase.net/reports/FBgn0023166.html gene 16-Dec-15 2015_12 FBgn0267578 CR45918 http://flybase.net/reports/FBgn0267578.html non_protein_coding_gene pri-mir-987 CR45918 16-Dec-15 2015_12 FBgn0034716 Oatp58Dc Organic anion transporting polypeptide 58Dc http://flybase.net/reports/FBgn0034716.html protein_coding_gene "0008514=organic anion transmembrane transporter activity, 0015347=sodium-independent organic anion transmembrane transporter activity" "0015711=organic anion transport, 0031427=response to methotrexate" 0016021=integral component of membrane "organic anion transporting polypeptide, oatp 58Dc, OATP, CG3380, OATP58Dc" "IPR004156=Organic anion transporter polypeptide OATP, IPR002350=Kazal domain, IPR020846=Major facilitator superfamily domain" CG3380 16-Dec-15 2015_12 viable FBgn0040206 krz kurtz http://flybase.net/reports/FBgn0040206.html "FBgn0028053, FBgn0039888" protein_coding_gene 0005515=protein binding "0042335=cuticle development, 0035204=negative regulation of lamellocyte differentiation, 0060189=positive regulation of protein desumoylation, 0031647=regulation of protein stability, 0002168=instar larval development, 0035641=locomotory exploration behavior, 0045751=negative regulation of Toll signaling pathway, 0045746=negative regulation of Notch signaling pathway, 0061099=negative regulation of protein tyrosine kinase activity, 0007369=gastrulation, 0050728=negative regulation of inflammatory response" 0005737=cytoplasm "Kurz, kurtz, unnamed, beta-arrestin, Kurtz, Krz, 0952/14, CG1487, l(3)S095214, kurtz-arrestin" "IPR014752=Arrestin, C-terminal, IPR014756=Immunoglobulin E-set, IPR017864=Arrestin, conserved site, IPR011022=Arrestin C-terminal-like domain, IPR011021=Arrestin-like, N-terminal, IPR000698=Arrestin, IPR014753=Arrestin, N-terminal" CG1487 16-Dec-15 2015_12 "ENSDARG00000011545(arrb2b),ENSDARG00000039215(arrb2a)" WBGene00000195(arr-1) "ENSXETG00000009605(ARRB1),ENSXETG00000017230(ARRB2)" "ENSMUSG00000018909(Arrb1),ENSMUSG00000060216(Arrb2)" "ENSG00000137486(ARRB1),ENSG00000141480(ARRB2)" " adult stage && oogenesis stage , larval stage | third instar , adult stage , embryonic stage , embryonic stage | stage 17 , embryonic stage | stage 16 , embryonic stage | stage <=8 , embryonic stage -- adult stage " " nurse cell

, larval deuterocerebrum

, ventral nerve cord | ventral

, oocyte

, cirri

, embryonic central nervous system

, embryonic/larval fat body

, dorsal pouch

, eye-antennal disc

, antennal sense organ

, organism | ubiquitous

, cephalopharyngeal skeleton

, dorsal mesothoracic disc | restricted

, embryonic/larval trachea

" "visible,somatic clone,melanotic mass phenotype,recessive,increased cell death,size defective,lethal - all die before end of larval stage,some die during third instar larval stage,sterile,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,locomotor behavior defective,viable,wild-type" "wing blade,somatic clone,imaginal disc,wing vein,1st posterior cell,ectopic,macrochaeta,melanotic mass,embryonic/larval fat body,lamellocyte,embryonic/first instar larval cuticle,presumptive embryonic/larval nervous system" FBgn0000664 fle femaleless http://flybase.net/reports/FBgn0000664.html gene "file(3)100, fle(3)100" 16-Dec-15 2015_12 "lethal,female,viable,male" FBgn0034721 CG11298 http://flybase.net/reports/FBgn0034721.html FBgn0063348 protein_coding_gene 0031110=regulation of microtubule polymerization or depolymerization BcDNA:AT10824 IPR000956=Stathmin family CG11298 16-Dec-15 2015_12 viable FBgn0266517 s-563.2 http://flybase.net/reports/FBgn0266517.html gene 16-Dec-15 2015_12 FBgn0002514 l(3)Sp6 lethal (3) Sp6 http://flybase.net/reports/FBgn0002514.html gene 16-Dec-15 2015_12 lethal FBgn0015354 anon-99Cc anon-99Cc http://flybase.net/reports/FBgn0015354.html gene 16-Dec-15 2015_12 FBgn0039588 CG12413 http://flybase.net/reports/FBgn0039588.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003743=translation initiation factor activity" "0006413=translational initiation, 0006412=translation" 0005739=mitochondrion "IPR023115=Translation initiation factor IF- 2, domain 3, IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12413 16-Dec-15 2015_12 ENSDARG00000063213(mtif2) YOL023W(IFM1) WBGene00009771(F46B6.6) ENSMUSG00000020459(Mtif2) ENSG00000085760(MTIF2) FBgn0031905 gudu gudu http://flybase.net/reports/FBgn0031905.html protein_coding_gene 0007291=sperm individualization "CG5155, Gudu" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR026959=Armadillo repeat-containing protein 4, IPR000225=Armadillo" CG5155 16-Dec-15 2015_12 ENSDARG00000055128 ENSXETG00000004553(ARMC4) ENSMUSG00000061802(Armc4) ENSG00000169126(ARMC4) "viable,male sterile" "spermatozoon,spermatid,sperm individualization complextub.PU,sperm individualization complexbam.THsimVP16" FBgn0259199 Snup Snurportin http://flybase.net/reports/FBgn0259199.html "FBgn0035362, FBgn0035363, FBan0032297, FBgn0052297" protein_coding_gene "0030621=U4 snRNA binding, 0030619=U1 snRNA binding, 0030620=U2 snRNA binding" "0015030=Cajal body, 0071254=cytoplasmic U snRNP body" "dSNUP, CG1247, CG42303, CG32297" CG42303 16-Dec-15 2015_12 ENSDARG00000008395(snupn) WBGene00017746(F23F1.5) ENSXETG00000015280(SNUPN) ENSMUSG00000055334(Snupn) ENSG00000169371(SNUPN) FBgn0014229 l(2)31Ej lethal (2) 31Ej http://flybase.net/reports/FBgn0014229.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0045073 Stim Stromal interaction molecule http://flybase.net/reports/FBgn0045073.html FBgn0030709 protein_coding_gene "0048763=calcium-induced calcium release activity, 0015279=store-operated calcium channel activity" "0032237=activation of store-operated calcium channel activity, 0007476=imaginal disc-derived wing morphogenesis, 0051533=positive regulation of NFAT protein import into nucleus, 0002115=store-operated calcium entry, 0022416=chaeta development, 0007155=cell adhesion" "0012505=endomembrane system, 0005886=plasma membrane" "dStim, stim1, stromal interaction molecule 1, CG9126, D-STIM, STIM, stromal interaction molecule, dstim, dSTIM, C-Stim, D-Stim, Drosophila Stromal interaction molecule" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG9126 16-Dec-15 2015_12 "ENSDARG00000060723(si:dkey-24p1.5),ENSDARG00000061560(LOC100005700),ENSDARG00000001776(LOC563901)" WBGene00021910(stim-1) ENSXETG00000018384(stim1) "ENSMUSG00000030987(Stim1),ENSMUSG00000039156(Stim2)" "ENSG00000167323(STIM1),ENSG00000109689(STIM2)" "visible,increased cell death,hypoactive,lethal - all die before end of larval stage,some die during larval stage,lethal,viable" "posterior wing margin,anterior wing margin,embryonic/larval fat body,mesothoracic tergum,microchaeta & mesothoracic tergumpnr-MD237,wing vein,eye,ommatidium,interommatidial bristle,microchaeta,wing margin bristle,ectopic,wing vein L5,distal,wing,wing hair,sensillum campaniformium,wing disc,S2 cell-line,trichogen cell,supernumerary" FBgn0085580 CG41254 http://flybase.net/reports/FBgn0085580.html FBan0041254 protein_coding_gene 16-Dec-15 2015_12 FBgn0030243 CG2186 http://flybase.net/reports/FBgn0030243.html protein_coding_gene CG2186 16-Dec-15 2015_12 ENSMUSG00000048271(Rbm33) ENSG00000184863(RBM33) "viable,fertile" DRSC19838 I 1.657352386 -0.836288979 1.092989747 -0.587815437 0.934306152 -0.253974705 FBgn0028506 CG4455 http://flybase.net/reports/FBgn0028506.html "FBgn0026574, FBgn0027876" protein_coding_gene "LD27171, BEST:LD27171, BG:DS09218.3" CG4455 16-Dec-15 2015_12 "viable,fertile,female fertile,visible,partially lethal - majority die" "eye,macrochaeta" FBgn0000866 fs(1)M61 female sterile (1) M61 http://flybase.net/reports/FBgn0000866.html gene 16-Dec-15 2015_12 FBgn0083254 E(smoDN)B-right Enhancer of smoDN group B-right http://flybase.net/reports/FBgn0083254.html gene 0007224=smoothened signaling pathway Group B-right 16-Dec-15 2015_12 "lethal,recessive,cell lethalcell lethal,somatic clone" FBgn0031861 CG17375 http://flybase.net/reports/FBgn0031861.html protein_coding_gene CG17375 16-Dec-15 2015_12 viable FBgn0013688 mt:srRNA mitochondrial small ribosomal RNA http://flybase.net/reports/FBgn0013688.html "FBgn0002867, FBgn0025234" rRNA_gene 0007279=pole cell formation "0005739=mitochondrion, 0005763=mitochondrial small ribosomal subunit, 0043186=P granule" "rRNA-12s, 12S rRNA, mtsrRNA, Small Subunit rRNA, anon-EST:fe2A4, mtrRNA, small rRNA, 12 s rRNA, anon-fast-evolving-2A4, srRNA, CR34096, 12S, rRNA-12 S, snRNA-d, 12 S rRNA, msrRNA" CR34096 16-Dec-15 2015_12 embryonic stage | stage 1-3 pole granule

FBgn0051805 CG31805 http://flybase.net/reports/FBgn0051805.html protein_coding_gene 0042060=wound healing CG31805 16-Dec-15 2015_12 viable FBgn0020643 Lcp65Ab2 Lcp65Ab2 http://flybase.net/reports/FBgn0020643.html "FBgn0002536, FBgn0042114, FBgn0047112" protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "LCP65Ab2, BcDNA:RE39879, L[[3]]CP5, Lcp-b, Lcp5, LCP-5, CP5, LCP5, Lcp65A-b, Lcp-b2, Lcp65Ab, DCP-beta, CG18773" IPR000618=Insect cuticle protein CG18773 16-Dec-15 2015_12 " larval stage , embryonic stage " FBgn0043467 064Ya 064Ya http://flybase.net/reports/FBgn0043467.html gene 0048149=behavioral response to ethanol unnamed 16-Dec-15 2015_12 chemical sensitive FBgn0024897 b6 b6 http://flybase.net/reports/FBgn0024897.html FBgn0025380 protein_coding_gene 0008030=neuronal pentraxin receptor activity "EG:9D2.1, B6, CG3100" IPR013320=Concanavalin A-like lectin/glucanase domain CG3100 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum FBgn0266208 CR44903 http://flybase.net/reports/FBgn0266208.html non_protein_coding_gene CR44903 16-Dec-15 2015_12 FBgn0037042 CG12984 http://flybase.net/reports/FBgn0037042.html protein_coding_gene CG12984 16-Dec-15 2015_12 "viable,fertile" FBgn0015714 Cyp6a17 Cytochrome P450-6a17 http://flybase.net/reports/FBgn0015714.html FBgn0033977 protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0040040=thermosensory behavior" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG10241, 6a17, Cyp6a17, cytochrome P450, ESTS:61D6S, 61D6S, Cyp6A17, cyp6a17" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG10241 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "temperature response defective,viable,fertile" FBgn0034292 CG5767 http://flybase.net/reports/FBgn0034292.html protein_coding_gene CT18118 IPR007931=Protein of unknown function DUF725 CG5767 16-Dec-15 2015_12 FBgn0036654 CG9692 http://flybase.net/reports/FBgn0036654.html protein_coding_gene CG9692 16-Dec-15 2015_12 male fertile FBgn0043016 91R 91R http://flybase.net/reports/FBgn0043016.html gene 91-R 16-Dec-15 2015_12 FBgn0267800 CR46125 http://flybase.net/reports/FBgn0267800.html non_protein_coding_gene CR46125 16-Dec-15 2015_12 FBgn0039202 CG13622 http://flybase.net/reports/FBgn0039202.html protein_coding_gene CG13622 16-Dec-15 2015_12 viable FBgn0016980 snRNA:K8 small nuclear RNA K8 http://flybase.net/reports/FBgn0016980.html snRNA_gene K8 16-Dec-15 2015_12 FBgn0000024 Ace Acetylcholine esterase http://flybase.net/reports/FBgn0000024.html protein_coding_gene "0004104=cholinesterase activity, 0042803=protein homodimerization activity, 0052689=carboxylic ester hydrolase activity, 0003990=acetylcholinesterase activity" "0006581=acetylcholine catabolic process, 0007268=synaptic transmission, 0007271=synaptic transmission, cholinergic, 0042426=choline catabolic process, 0042331=phototaxis, 0046683=response to organophosphorus, 0001507=acetylcholine catabolic process in synaptic cleft, 0046681=response to carbamate" "0005737=cytoplasm, 0045202=synapse, 0005886=plasma membrane, 0016020=membrane" "Acetylcholinesterase, acetylcholinesterase, l(3)87Ed, DmAChE, ace-2, dmAChE, AcChE, dAChE, FBgn0000024, CHE, ACE, acetyl choline esterase, AChE, AchE, CG17907, l(3)26, ache, ace, acetylcholine esterase" "IPR000997=Cholinesterase, IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site, IPR001445=Acetylcholinesterase, insect, IPR019819=Carboxylesterase type B, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG17907 16-Dec-15 2015_12 ENSDARG00000031796(ache) WBGene00000035(ace-1) "ENSXETG00000006497(),ENSXETG00000008731(),ENSXETG00000017226(ACHE)" "ENSMUSG00000023328(Ache),ENSMUSG00000027792(Bche)" "ENSG00000114200(BCHE),ENSG00000087085(ACHE)" "lethal,recessive,viable,fertile,neuroanatomy defective,wild-type,chemical resistant,partially lethal - majority die,phototaxis defective,heat sensitive,somatic clone,neurophysiology defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,non-enhancer of variegation,non-suppressor of variegation,locomotor behavior defective,electrophoretic variant,uncoordinated,suppressor of variegation,partially,optomotor response defective,visual behavior defective,courtship behavior defective,cold sensitive,mating defective,hypoactive,male,paralytic" "NMJ bouton,eye photoreceptor cell & axon & stage 2 third instar larva | somatic clone,eye photoreceptor cell & axon & stage 2 third instar larva | somatic clone | cell non-autonomous,aCC neuron,RP2 motor neuron,adult brain & neuropil | conditional ts,central nervous system,somatic clone" FBgn0030969 Usp39 Ubiquitin specific protease 39 http://flybase.net/reports/FBgn0030969.html protein_coding_gene "0008270=zinc ion binding, 0004843=ubiquitin-specific protease activity, 0036459=ubiquitinyl hydrolase activity" "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome "CG7288, Q9VWP1" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001607=Zinc finger, UBP-type, IPR028889=Ubiquitin specific protease domain" CG7288 16-Dec-15 2015_12 ENSDARG00000041908(usp39) YFR005C(SAD1) WBGene00017280(F09D1.1) ENSXETG00000001269(USP39) ENSMUSG00000056305(Usp39) ENSG00000168883(USP39) "visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,locomotor behavior defective,heat sensitive" "wing,wing margin bristle,scutellar bristle" DRSC20032 IEK -0.534067363 1.788545429 -1.239257427 2.267994632 2.148869973 -0.579149805 FBgn0000735 fs(1)1867 female sterile (1) 1867 http://flybase.net/reports/FBgn0000735.html gene 16-Dec-15 2015_12 "female sterile soma-dependent,recessive,visible,dominant" "ovariole,oocyte,follicle cell,macrochaeta" FBgn0002632 E(spl)m6-BFM "Enhancer of split m6, Bearded family member" http://flybase.net/reports/FBgn0002632.html protein_coding_gene "0031625=ubiquitin protein ligase binding, 0005515=protein binding" "0001708=cell fate specification, 0007219=Notch signaling pathway, 0007423=sensory organ development" "Enhancer of split region transcript m6, CG8354, Enhancer of Split Region Transcript m6, m6, E(spl) region transcript m6, HLHm6, E(spl)m6, DmelCG8354, M6, E(spl)M6" CG8354 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage , embryonic stage | stage 13-15 , embryonic stage | 10-14 hr " " dorsal mesothoracic disc | restricted

, embryonic central nervous system

, ventral nerve cord

,

segmentally repeated , embryonic peripheral nervous system

, embryonic brain

, embryonic/larval midgut | restricted

" "visible,viable" "macrochaeta,microchaeta,sensory mother cell,medial triple row,chemosensory ventral triple row bristle,dorsal triple row,sensillum campaniformium of dorsal radius,wing margin,wing margin bristle" FBgn0010403 Obp83b Odorant-binding protein 83b http://flybase.net/reports/FBgn0010403.html protein_coding_gene "0005549=odorant binding, 0005550=pheromone binding" 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp83b, PBP-H1, Pheromone-binding protein Homolog 1, Obp83b, obp83b, Os-E, CG11422, Olfactory-specific E, 83b, OS-E" IPR006170=Pheromone/general odorant binding protein CG11422 16-Dec-15 2015_12 adult stage " antennal segment 3

, sensillum trichodeum of antennal segment 3

" "viable,fertile" FBgn0035997 phol pleiohomeotic like http://flybase.net/reports/FBgn0035997.html protein_coding_gene "0003677=DNA binding, 0043565=sequence-specific DNA binding, 0046872=metal ion binding" 0016458=gene silencing 0005634=nucleus "Pleiohomeotic-like, Phol, Pho-like, PHO-like, pleiohomeotic-like, PHO-LIKE, Pleiohomeotic like, pho-like, PHOL, CG3445" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG3445 16-Dec-15 2015_12 "ENSDARG00000042796(yy1a),ENSDARG00000027978(yy1b)" WBGene00018990(klf-1) ENSXETG00000002527() "viable,fertile,male fertile,female sterile,recessive,lethal,maternal effect,germline clone" DRSC10367 I -0.055054956 1.730562385 -0.107335836 -0.09410573 0.105551327 0.242137691 FBgn0086072 snoRNA:Or-CD11a http://flybase.net/reports/FBgn0086072.html snoRNA_gene "DmOr_cd11a, CR34701, Or-cd11a" CR34701 16-Dec-15 2015_12 FBgn0267070 CR45514 http://flybase.net/reports/FBgn0267070.html non_protein_coding_gene CR45514 16-Dec-15 2015_12 FBgn0005113 l(1)184 lethal (1) 184 http://flybase.net/reports/FBgn0005113.html gene 16-Dec-15 2015_12 lethal eye FBgn0050298 tRNA:CR30298 transfer RNA:CR30298 http://flybase.net/reports/FBgn0050298.html "FBgn0011988, FBgn0060042" tRNA_gene "0033437=ACU codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:T3:47F, transfer RNA:thr3:47F, chr2R.trna87-ThrAGT, CR30298, tRNA[Thr][[3]], tRNA:T:AGT:AE002787-b, tRNA:thr3:47F, AE002787.trna28-ThrAGT, tRNA[[Thr]]" CR30298 16-Dec-15 2015_12 FBgn0026560 CD98 CD98 http://flybase.net/reports/FBgn0026560.html gene 16-Dec-15 2015_12 FBgn0082193 arm::pan arm::pan http://flybase.net/reports/FBgn0082193.html engineered_fusion_gene 16-Dec-15 2015_12 "embryonic/first instar larval cuticle,denticle,ectopic" FBgn0014320 l(3)ry146 lethal (3) ry146 http://flybase.net/reports/FBgn0014320.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0067653 sd-2 sd-2 http://flybase.net/reports/FBgn0067653.html gene "0007270=neuron-neuron synaptic transmission, 0042331=phototaxis" complementation group 2 16-Dec-15 2015_12 "lethal,neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective" "photoreceptor cell & axon | somatic clone,medulla,somatic clone,lamina" FBgn0000470 dlv deltoid veins http://flybase.net/reports/FBgn0000470.html gene devoid veins 16-Dec-15 2015_12 "viable,fertile,visible,body color defective" "wing,wing vein,eye,adult thorax,adult abdomen" FBgn0043028 l(2)42Eb lethal (2) 42Eb http://flybase.net/reports/FBgn0043028.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0028336 l(1)G0255 lethal (1) G0255 http://flybase.net/reports/FBgn0028336.html "FBgn0027231, FBgn0029889" protein_coding_gene 0004333=fumarate hydratase activity "0006106=fumarate metabolic process, 0006099=tricarboxylic acid cycle" "0045239=tricarboxylic acid cycle enzyme complex, 0005739=mitochondrion, 0005737=cytoplasm" "CG 4094, CG4094, FBgn0029889, l(1)G0255, l(1)G0290" "IPR024083=Fumarase/histidase, N-terminal, IPR022761=Fumarate lyase, N-terminal, IPR000362=Fumarate lyase family, IPR020557=Fumarate lyase, conserved site, IPR005677=Fumarate hydratase, class II, IPR008948=L-Aspartase-like, IPR018951=Fumarase C, C-terminal" CG4094 16-Dec-15 2015_12 ENSDARG00000068620 YPL262W(FUM1) WBGene00001503(fum-1) ENSXETG00000006529(FH) ENSMUSG00000026526(Fh1) ENSG00000091483(FH) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" trichogen cell FBgn0039153 CG5463 http://flybase.net/reports/FBgn0039153.html protein_coding_gene 0050567=glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity 0006425=glutaminyl-tRNA aminoacylation 0005739=mitochondrion "IPR018027=Asn/Gln amidotransferase, IPR003789=Aspartyl/glutamyl-tRNA amidotransferase subunit B-related, IPR006075=Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic, IPR017959=Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E, IPR004413=Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit" CG5463 16-Dec-15 2015_12 ENSDARG00000037309(zgc:103736) YBL080C(PET112) WBGene00016524(C39B5.6) ENSMUSG00000028085(Pet112l) ENSG00000059691(PET112) "partially lethal - majority die,visible" trichogen cell FBgn0053172 CG33172 http://flybase.net/reports/FBgn0053172.html FBgn0030689 protein_coding_gene CG8473 "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG33172 16-Dec-15 2015_12 YPL183C(RTT10) WBGene00013204(Y54E5B.2) ENSXETG00000009340(WDR6) ENSMUSG00000066357(Wdr6) ENSG00000178252(WDR6) viable FBgn0010659 l(2)10425 lethal (2) 10425 http://flybase.net/reports/FBgn0010659.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0022156 l(2)k05812 lethal (2) k05812 http://flybase.net/reports/FBgn0022156.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264817 pre-lola-G http://flybase.net/reports/FBgn0264817.html protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" CG44025 "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG44025 16-Dec-15 2015_12 FBgn0028280 l(1)G0417 lethal (1) G0417 http://flybase.net/reports/FBgn0028280.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0044035 Mod(rst)D264 Mod(rst)D264 http://flybase.net/reports/FBgn0044035.html gene 0001745=compound eye morphogenesis D264 16-Dec-15 2015_12 viable eye FBgn0267424 CR45777 http://flybase.net/reports/FBgn0267424.html pseudogene_attribute CR45777 16-Dec-15 2015_12 FBgn0031688 Cyp28d2 Cyp28d2 http://flybase.net/reports/FBgn0031688.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity, 0004497=monooxygenase activity, 0005506=iron ion binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "28d2, CG6081, cytochrome P450" "IPR017972=Cytochrome P450, conserved site, IPR002403=Cytochrome P450, E-class, group IV, IPR001128=Cytochrome P450" CG6081 16-Dec-15 2015_12 YHR007C(ERG11) viable FBgn0065559 l(2)SH0997 lethal (2) SH0997 http://flybase.net/reports/FBgn0065559.html gene l(2)SH2 0997 16-Dec-15 2015_12 "lethal,recessive" FBgn0066364 fey forever young http://flybase.net/reports/FBgn0066364.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal" FBgn0000628 eym eye missing http://flybase.net/reports/FBgn0000628.html gene 16-Dec-15 2015_12 "visible,recessive,fertile,partially lethal - majority die,some die during pupal stage" eye FBgn0264343 CG43799 http://flybase.net/reports/FBgn0264343.html protein_coding_gene CG43799 16-Dec-15 2015_12 FBgn0036878 Cpr76Ba Cuticular protein 76Ba http://flybase.net/reports/FBgn0036878.html protein_coding_gene "0008012=structural constituent of adult chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG9283, DmelCpr76Ba" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG9283 16-Dec-15 2015_12 viable DRSC27858 K -0.065101407 -0.495237729 -0.032128727 0.483682273 4.070953529 1.864960554 FBgn0262763 Mst77Y-14ë¬ Male-specific pseudogene 77Y 14 http://flybase.net/reports/FBgn0262763.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0265938 CR44725 http://flybase.net/reports/FBgn0265938.html non_protein_coding_gene CR44725 16-Dec-15 2015_12 FBgn0060799 l(3)S057401 lethal (3) S057401 http://flybase.net/reports/FBgn0060799.html gene 0574/01 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0005049 extended extended http://flybase.net/reports/FBgn0005049.html gene ext 16-Dec-15 2015_12 "visible,viable,fertile" wing FBgn0004495 exb extreme bar http://flybase.net/reports/FBgn0004495.html gene 16-Dec-15 2015_12 visible "eye,ocellus" FBgn0033033 scaf scarface http://flybase.net/reports/FBgn0033033.html FBgn0033034 protein_coding_gene 0004252=serine-type endopeptidase activity "0048803=imaginal disc-derived male genitalia morphogenesis, 0006508=proteolysis" 0005615=extracellular space "CG15900, CG11066, Scarface, scarface, scarf, SPH142" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG11066 16-Dec-15 2015_12 "viable,partially lethal - majority die,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "adult head,embryonic/first instar larval cuticle" FBgn0021746 Bm Bumpy http://flybase.net/reports/FBgn0021746.html gene 16-Dec-15 2015_12 "lethal,recessive,visible,dominant" "ommatidium,eye" FBgn0060819 l(3)S052401b lethal (3) S052401b http://flybase.net/reports/FBgn0060819.html gene 0524/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0265523 Smr Smrter http://flybase.net/reports/FBgn0265523.html "FBgn0263865, FBgn0024308, FBgn0028313, FBgn0045877, FBgn0030416, FBgn0027321, FBgn0029797, FBgn0261376" protein_coding_gene "0003677=DNA binding, 0003682=chromatin binding, 0003714=transcription corepressor activity, 0005515=protein binding" "0006909=phagocytosis, 0045746=negative regulation of Notch signaling pathway, 0007346=regulation of mitotic cell cycle, 0045892=negative regulation of transcription, DNA-templated, 0007476=imaginal disc-derived wing morphogenesis" "0005829=cytosol, 0017053=transcriptional repressor complex, 0005700=polytene chromosome, 0005654=nucleoplasm" "SMRTER, SMRT-related ecdysone receptor-interacting factor, smr, silencing mediator of retinoid and thyroid hormone receptors-related ecdysone receptor-interacting factor, l(1)G0060, CG12719, Smarter, lethal (1) G0060, SMRT-related ecdysone receptor interacting factor, SMR, E52, lincRNA.983, anon-WO0153538.73, SANT domain protein, CG4013, l(1)G0361" "IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like, IPR017884=SANT domain" CG4013 16-Dec-15 2015_12 ENSXETG00000006720(ncor1) "ENSMUSG00000029478(Ncor2),ENSMUSG00000018501(Ncor1)" "ENSG00000141027(NCOR1),ENSG00000196498(NCOR2)" DRSC22986 K 2.858334109 0.224767518 FBgn0264477 CG43885 http://flybase.net/reports/FBgn0264477.html protein_coding_gene CG43885 16-Dec-15 2015_12 FBgn0260358 GSd238 http://flybase.net/reports/FBgn0260358.html gene 16-Dec-15 2015_12 lethal FBgn0069944 CG41096 http://flybase.net/reports/FBgn0069944.html protein_coding_gene 16-Dec-15 2015_12 FBgn0003318 soft-brown soft brown http://flybase.net/reports/FBgn0003318.html gene sb 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0035853 UbcE2M Ubiquitin conjugating enzyme E2M http://flybase.net/reports/FBgn0035853.html FBgn0062104 protein_coding_gene "0019788=NEDD8 transferase activity, 0004842=ubiquitin-protein transferase activity, 0018169=ribosomal S6-glutamic acid ligase activity" "0045116=protein neddylation, 0006464=cellular protein modification process, 0045879=negative regulation of smoothened signaling pathway" "CG7375, anon-WO0118547.309, dUbc12, UbcD12, Ubiquitin conjugating enzyme 12, Ubc12" "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG7375 16-Dec-15 2015_12 ENSDARG00000025754(zgc:77005) YLR306W(UBC12) ENSXETG00000018326(ube2m) ENSMUSG00000005575(Ube2m) ENSG00000130725(UBE2M) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC10828 E 0.468169387 0.234486297 2.395199241 1.465022276 1.067751269 -0.147040037 FBgn0033388 CG8046 http://flybase.net/reports/FBgn0033388.html protein_coding_gene 0004368=glycerol-3-phosphate dehydrogenase activity "0055085=transmembrane transport, 0006072=glycerol-3-phosphate metabolic process, 0055114=oxidation-reduction process" "0009331=glycerol-3-phosphate dehydrogenase complex, 0016021=integral component of membrane" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily, IPR000447=FAD-dependent glycerol-3-phosphate dehydrogenase" CG8046 16-Dec-15 2015_12 ENSDARG00000026149(slc46a1) YJL163C() "WBGene00021159(Y4C6B.5),WBGene00009582(F40F9.5),WBGene00012811(Y43F8A.5)" ENSXETG00000023785(SLC46A1) "ENSMUSG00000020829(Slc46a1),ENSMUSG00000029650(Slc46a3)" "ENSG00000076351(SLC46A1),ENSG00000139508(SLC46A3)" viable FBgn0024271 ZAM\gag gag http://flybase.net/reports/FBgn0024271.html transposable_element_gene "ZAM gag, ORF1, gag" 16-Dec-15 2015_12 FBgn0262146 MtnE Metallothionein E http://flybase.net/reports/FBgn0262146.html protein_coding_gene 0046872=metal ion binding "0010043=response to zinc ion, 0010272=response to silver ion, 0046689=response to mercury ion, 0046688=response to copper ion, 0071585=detoxification of cadmium ion" "CG42872, DMG8-chr3R.29.007" "IPR000966=Metallothionein, family 5, Diptera" CG42872 16-Dec-15 2015_12 FBgn0061506 l(2)24Ad lethal (2) 24Ad http://flybase.net/reports/FBgn0061506.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0061487 plpg polyplegic http://flybase.net/reports/FBgn0061487.html gene 0007386=compartment pattern specification 16-Dec-15 2015_12 FBgn0060309 l(3)S148016 lethal (3) S148016 http://flybase.net/reports/FBgn0060309.html gene 1480/16 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053287 CG33287 http://flybase.net/reports/FBgn0053287.html FBgn0037041 protein_coding_gene CG12982 IPR022110=Casc1 domain CG33287 16-Dec-15 2015_12 "viable,fertile" FBgn0005731 l(1)TK207 lethal (1) TK207 http://flybase.net/reports/FBgn0005731.html gene l207 16-Dec-15 2015_12 "lethal,recessive" "eye,lamina" FBgn0034460 CG18367 http://flybase.net/reports/FBgn0034460.html FBgn0040731 protein_coding_gene CG15123 CG18367 16-Dec-15 2015_12 viable FBgn0030571 CG14414 http://flybase.net/reports/FBgn0030571.html FBgn0063363 protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" "BcDNA:AT01764, cg14414" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG14414 16-Dec-15 2015_12 ENSDARG00000044255(rbm18) ENSXETG00000016328(rbm18) ENSMUSG00000026889(Rbm18) ENSG00000119446(RBM18) "viable,fertile,visible" trichogen cell FBgn0019692 l(3)68Fi lethal (3) 68Fi http://flybase.net/reports/FBgn0019692.html gene l(3)68Fe 16-Dec-15 2015_12 lethal FBgn0263327 CR43408 http://flybase.net/reports/FBgn0263327.html non_protein_coding_gene CR43408 16-Dec-15 2015_12 FBgn0085525 CG40849 http://flybase.net/reports/FBgn0085525.html FBan0040849 protein_coding_gene 16-Dec-15 2015_12 FBgn0266948 CR45399 http://flybase.net/reports/FBgn0266948.html non_protein_coding_gene CR45399 16-Dec-15 2015_12 FBgn0262431 mir-1003 mir-1003 stem loop http://flybase.net/reports/FBgn0262431.html "FBgn0250799, FBgn0262280" miRNA_gene 0035278=negative regulation of translation involved in gene silencing by miRNA "CR42987, 1003, dme-mir-1003, miR-1003" CR42987 16-Dec-15 2015_12 "visible,viable,lethal" "wing,wing vein" FBgn0053424 5SrRNA:CR33424 5SrRNA:CR33424 http://flybase.net/reports/FBgn0053424.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33424 CR33424 16-Dec-15 2015_12 FBgn0082366 EP3645 EP3645 http://flybase.net/reports/FBgn0082366.html gene 16-Dec-15 2015_12 increased cell death spermatogonium FBgn0022360 Scbp Soluble calcium-binding protein http://flybase.net/reports/FBgn0022360.html gene 0005509=calcium ion binding SCBP 16-Dec-15 2015_12 FBgn0000690 flrdN flight reduced N http://flybase.net/reports/FBgn0000690.html gene 16-Dec-15 2015_12 "jumping defective,flightless,heat sensitive,flight defective" FBgn0031312 Tango14 Transport and Golgi organization 14 http://flybase.net/reports/FBgn0031312.html FBgn0062416 protein_coding_gene "0016765=transferase activity, transferring alkyl or aryl (other than methyl) groups" "0009306=protein secretion, 0035220=wing disc development" 0005783=endoplasmic reticulum "Tango 14, CG4775, lethal (2) k00619, TANGO14, BcDNA:SD10843, l(2)k00619" IPR001441=Decaprenyl diphosphate synthase-like CG4775 16-Dec-15 2015_12 ENSDARG00000027813(nus1) ENSXETG00000025077(NUS1) ENSMUSG00000023068(Nus1) ENSG00000153989(NUS1) "lethal,recessive" FBgn0052333 CG32333 http://flybase.net/reports/FBgn0052333.html "FBgn0035200, FBgn0035201" protein_coding_gene "CG9146, CG9137" "IPR029058=Alpha/Beta hydrolase fold, IPR022122=Protein FAM135, IPR007751=Domain of unknown function DUF676, lipase-like" CG32333 16-Dec-15 2015_12 ENSDARG00000059843(LOC566435) WBGene00015635(C09D4.4) ENSXETG00000017907(FAM135A) "ENSMUSG00000026153(Fam135a),ENSMUSG00000036800" "ENSG00000082269(FAM135A),ENSG00000147724(FAM135B)" "viable,fertile,visible" "antenna,leg,ectopic" FBgn0042166 CG18846 http://flybase.net/reports/FBgn0042166.html protein_coding_gene 16-Dec-15 2015_12 FBgn0261067 LSm1 http://flybase.net/reports/FBgn0261067.html "FBgn0034600, FBgn0259792" protein_coding_gene "0006396=RNA processing, 0000398=mRNA splicing, via spliceosome, 0033962=cytoplasmic mRNA processing body assembly" "0030532=small nuclear ribonucleoprotein complex, 0005681=spliceosomal complex" "CG4279, Lsm1" "IPR001163=LSM domain, eukaryotic/archaea-type, IPR010920=LSM domain" CG4279 16-Dec-15 2015_12 ENSDARG00000043177(zgc:101136) YJL124C(LSM1) WBGene00003076(lsm-1) ENSXETG00000009004(lsm1) ENSMUSG00000037296(Lsm1) ENSG00000175324(LSM1) FBgn0266763 CR45228 http://flybase.net/reports/FBgn0266763.html non_protein_coding_gene CR45228 16-Dec-15 2015_12 FBgn0035623 mthl2 methuselah-like 2 http://flybase.net/reports/FBgn0035623.html "FBgn0046544, FBgn0046545" protein_coding_gene 0004930=G-protein coupled receptor activity "0008340=determination of adult lifespan, 0007186=G-protein coupled receptor signaling pathway, 0042594=response to starvation" 0016021=integral component of membrane "anon-WO0170980.28, Methuselah-like 2, Mth-like 2, CG17795, anon-WO0170980.29, Mth-2, mth-like 2" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR010596=Methuselah, N-terminal domain, IPR023311=Methuselah ectodomain, domain 2, IPR017981=GPCR, family 2-like, IPR000832=GPCR, family 2, secretin-like" CG17795 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" "viable,fertile" FBgn0065164 l(3)SH035 lethal (3) SH035 http://flybase.net/reports/FBgn0065164.html gene l(2)SH3 035 16-Dec-15 2015_12 "lethal,recessive" FBgn0026260 bundled bundled http://flybase.net/reports/FBgn0026260.html gene 16-Dec-15 2015_12 FBgn0032369 CG6614 http://flybase.net/reports/FBgn0032369.html protein_coding_gene "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1" CG6614 16-Dec-15 2015_12 viable FBgn0069104 mus320 mutagen-sensitive 320 http://flybase.net/reports/FBgn0069104.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0045479 Gr64a Gustatory receptor 64a http://flybase.net/reports/FBgn0045479.html "FBgn0035485, FBgn0041217, FBgn0052261" protein_coding_gene "0008527=taste receptor activity, 0033041=sweet taste receptor activity" "0050916=sensory perception of sweet taste, 0050909=sensory perception of taste, 0007637=proboscis extension reflex, 0050912=detection of chemical stimulus involved in sensory perception of taste, 0034289=detection of maltose stimulus, 0051594=detection of glucose, 0009731=detection of sucrose stimulus" 0016021=integral component of membrane "GR64a, Gustatory receptor LU.3, Gr64, CG32261, LU.3, Gr64A1, CG14986, Dmel64a, GRLU.3, GrLU3" IPR009318=Gustatory receptor CG32261 16-Dec-15 2015_12 WBGene00001804(gur-3) "taste perception defective,neurophysiology defective,proboscis extension reflex defective,viable,fertile" large labellar taste bristle DRSC21713 IE 2.459680437 -0.244616344 1.609006979 0.421405181 0.022541583 -0.355117504 FBgn0039956 CG17418 http://flybase.net/reports/FBgn0039956.html protein_coding_gene 16-Dec-15 2015_12 FBgn0035007 CG3492 http://flybase.net/reports/FBgn0035007.html FBgn0044615 protein_coding_gene "0051082=unfolded protein binding, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0000413=protein peptidyl-prolyl isomerization, 0006457=protein folding" anon-WO0140519.253 "IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000=Cyclophilin-like domain" CG3492 16-Dec-15 2015_12 viable FBgn0085293 CG34264 http://flybase.net/reports/FBgn0085293.html protein_coding_gene HDC07730 CG34264 16-Dec-15 2015_12 FBgn0034322 CG18536 http://flybase.net/reports/FBgn0034322.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG18536 16-Dec-15 2015_12 viable FBgn0260469 CR14578 http://flybase.net/reports/FBgn0260469.html "FBgn0040059, FBgn0058105, FBan0014578" pseudogene_attribute "CG14578, CG40105" CR14578 16-Dec-15 2015_12 FBgn0264810 Pburs Partner of Bursicon http://flybase.net/reports/FBgn0264810.html "FBgn0003161, FBgn0032546" protein_coding_gene "0071855=neuropeptide receptor binding, 0005184=neuropeptide hormone activity" "0007593=chitin-based cuticle sclerotization, 0007186=G-protein coupled receptor signaling pathway, 0018990=ecdysis, chitin-based cuticle, 0090175=regulation of establishment of planar polarity" "0031395=bursicon neuropeptide hormone complex, 0005576=extracellular region" "Burs beta, CG15284, bursicon beta-subunit, bursbeta, burs-beta, pupal, partner of bursicon, A, bur &gr;, pads-b, Bur beta, Partner of bursicon, bursicon beta, burs beta, pup, PBURS, partner of burs, pu, Bursicon beta subunit, bursicon, Partner of burs, Bursbeta, pburs, lethal group A" CG15284 16-Dec-15 2015_12 FBgn0005296 mei-2606 meiotic 2606 http://flybase.net/reports/FBgn0005296.html gene "meiotic 2696, mei-2696, 2606" 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0032768 CG17564 http://flybase.net/reports/FBgn0032768.html protein_coding_gene IPR025252=Domain of unknown function DUF4200 CG17564 16-Dec-15 2015_12 ENSDARG00000035550(LOC100001777) "ENSG00000186710(CCDC42B),ENSG00000161973(CCDC42)" viable FBgn0060747 l(3)S065303 lethal (3) S065303 http://flybase.net/reports/FBgn0060747.html gene 0653/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0243586 Tb Tubby http://flybase.net/reports/FBgn0243586.html "FBgn0039446, FBgn0003668" protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0010171=body morphogenesis, 0040003=chitin-based cuticle development" 0005578=proteinaceous extracellular matrix "TweedleA, TwdlA, CG5480, Tu" IPR004145=Domain of unknown function DUF243 CG5480 16-Dec-15 2015_12 DRSC15815 K 0.312675537 -0.15122553 0.12419505 -0.311329107 1.526959221 0.787314656 FBgn0065457 l(2)SH1385 lethal (2) SH1385 http://flybase.net/reports/FBgn0065457.html gene l(2)SH2 1385 16-Dec-15 2015_12 "lethal,recessive" FBgn0039272 CG11836 http://flybase.net/reports/FBgn0039272.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP23 "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG11836 16-Dec-15 2015_12 "ENSDARG00000056324(zgc:123295),ENSDARG00000046140(zgc:112038),ENSDARG00000055644(zgc:101788),ENSDARG00000070713(zgc:162180),ENSDARG00000070710(wu:fk80d04),ENSDARG00000061858(zgc:153968),ENSDARG00000056773(zgc:163079),ENSDARG00000052064(LOC571079),ENSDARG00000063444,ENSDARG00000070518,ENSDARG00000019714" WBGene00006619(try-1) ENSXETG00000010124(TEgg123i01.1) "ENSMUSG00000054537(Tmprss11e),ENSMUSG00000048764(Tmprss11f)" "lethal,recessive,viable" FBgn0013619 l(3)W33B lethal (3) W33B http://flybase.net/reports/FBgn0013619.html gene 16-Dec-15 2015_12 lethal FBgn0037206 CG12768 http://flybase.net/reports/FBgn0037206.html protein_coding_gene IPR006578=MADF domain CG12768 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265977 CR44756 http://flybase.net/reports/FBgn0265977.html non_protein_coding_gene CR44756 16-Dec-15 2015_12 FBgn0001631 l(1)dn8 lethal (1) discs normal 8 http://flybase.net/reports/FBgn0001631.html gene l(1)d.norm.-8 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037207 Mes2 Mesoderm-expressed 2 http://flybase.net/reports/FBgn0037207.html protein_coding_gene "0002168=instar larval development, 0001700=embryonic development via the syncytial blastoderm, 0007444=imaginal disc development, 0018990=ecdysis, chitin-based cuticle" 0005634=nucleus "adfR, Mes2, mes2, CG11100" IPR006578=MADF domain CG11100 16-Dec-15 2015_12 embryonic stage | cellular blastoderm mesoderm anlage

"lethal,hypoactive,body size defective,germline clone,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of larval stage,some die during larval stage" "embryonic/first instar larval cuticle,germline clone,embryonic dorsal epidermis | dorsal closure stage,embryonic leading edge cell,embryonic epidermis,wing,haltere" DRSC11632 IEK -0.095494179 -1.597528568 -3.332453545 -0.469981367 1.194888558 5.160337761 FBgn0062608 Mod(var)1328 Mod(var)1328 http://flybase.net/reports/FBgn0062608.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1328 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0065432 l(2)SH1489 lethal (2) SH1489 http://flybase.net/reports/FBgn0065432.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0051054 CR31054 http://flybase.net/reports/FBgn0051054.html pseudogene_attribute CG31054 CR31054 16-Dec-15 2015_12 DRSC22134 E 0.535374978 0.875818253 2.354701031 1.503626397 -0.033511893 -0.329952562 FBgn0031636 CG12194 http://flybase.net/reports/FBgn0031636.html FBgn0027769 protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane anon-EST:Posey105 "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG12194 16-Dec-15 2015_12 ENSXETG00000012456(MFSD1) ENSMUSG00000027775(Mfsd1) ENSG00000118855(MFSD1) viable FBgn0266430 CG45060 http://flybase.net/reports/FBgn0266430.html protein_coding_gene "CG32696, CG42262, CG15245, CG15246" CG45060 16-Dec-15 2015_12 viable FBgn0267862 CR46150 http://flybase.net/reports/FBgn0267862.html pseudogene_attribute CG12717-related CR46150 16-Dec-15 2015_12 FBgn0031273 CG2839 http://flybase.net/reports/FBgn0031273.html protein_coding_gene "IPR016186=C-type lectin-like, IPR001304=C-type lectin, IPR016187=C-type lectin fold" CG2839 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC00544 K -0.8759697 0.366147364 -0.375135352 0.837865786 -0.097954025 -1.552084745 FBgn0259651 B0326 http://flybase.net/reports/FBgn0259651.html gene 16-Dec-15 2015_12 visible "wing sensillum,ectopic,chaeta,wing,distal" FBgn0025756 l(3)93DFf lethal (3) 93DFf http://flybase.net/reports/FBgn0025756.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0064168 l(3)68.43 lethal (3) 68.43 http://flybase.net/reports/FBgn0064168.html gene "0007300=ovarian nurse cell to oocyte transport, 0007301=female germline ring canal formation" 68.43 16-Dec-15 2015_12 lethal "nurse cell ring canal,germline clone" FBgn0037772 Spn85F Serpin 85F http://flybase.net/reports/FBgn0037772.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity 0005615=extracellular space CG12807 "IPR023795=Serpin, conserved site, IPR000215=Serpin family, IPR023796=Serpin domain" CG12807 16-Dec-15 2015_12 FBgn0037998 CG4848 http://flybase.net/reports/FBgn0037998.html protein_coding_gene CG4848 16-Dec-15 2015_12 WBGene00003258(cogc-1) ENSXETG00000009979(COG1) ENSMUSG00000018661(Cog1) ENSG00000166685(COG1) viable FBgn0021923 l(2)k11226 lethal (2) k11226 http://flybase.net/reports/FBgn0021923.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0065294 l(2)SH2002 lethal (2) SH2002 http://flybase.net/reports/FBgn0065294.html gene l(2)SH2 2002 16-Dec-15 2015_12 "lethal,recessive" FBgn0263706 CG43658 http://flybase.net/reports/FBgn0263706.html "FBgn0030843, FBgn0030842" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0035025=positive regulation of Rho protein signal transduction, 0035023=regulation of Rho protein signal transduction, 0007480=imaginal disc-derived leg morphogenesis" "CG8557, CG12432" "IPR000219=Dbl homology (DH) domain, IPR001849=Pleckstrin homology domain, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG43658 16-Dec-15 2015_12 "ENSXETG00000011608(ARHGEF10),ENSXETG00000014794(ARHGEF10L)" "ENSMUSG00000071176(Arhgef10),ENSMUSG00000040964(Arhgef10l)" "ENSG00000104728(ARHGEF10),ENSG00000074964(ARHGEF10L)" FBgn0261113 Xrp1 http://flybase.net/reports/FBgn0261113.html "FBgn0038661, FBgn0025952, FBgn0010781" protein_coding_gene "0046983=protein dimerization activity, 0003677=DNA binding" "0009987=cellular process, 0042048=olfactory behavior, 0007476=imaginal disc-derived wing morphogenesis, 0051276=chromosome organization, 0008285=negative regulation of cell proliferation" "anon-EST:Liang-2.44, DM28, clone 2.44, xrp1, 2515, lethal (3) 02515, l(3)02515, XRP1, CG17836" "IPR017956=AT hook, DNA-binding motif" CG17836 16-Dec-15 2015_12 FBgn0083081 linc lincoyan http://flybase.net/reports/FBgn0083081.html gene 16-Dec-15 2015_12 FBgn0026563 CG1979 http://flybase.net/reports/FBgn0026563.html FBgn0063238 protein_coding_gene "BG:DS00464.1, BcDNA:GH19145" CG1979 16-Dec-15 2015_12 viable DRSC24707 K 0.552827875 -0.045677339 -0.735371262 -0.29379157 -1.000593264 -1.635708155 FBgn0085404 CG34375 http://flybase.net/reports/FBgn0085404.html "FBgn0039037, FBgn0039036" protein_coding_gene 0008270=zinc ion binding "0006511=ubiquitin-dependent protein catabolic process, 0007275=multicellular organismal development" 0005634=nucleus "CG13835, CG13834" "IPR004162=E3 ubiquitin-protein ligase SIN-like, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001478=PDZ domain, IPR001841=Zinc finger, RING-type" CG34375 16-Dec-15 2015_12 viable FBgn0265736 CR44543 http://flybase.net/reports/FBgn0265736.html non_protein_coding_gene CR44543 16-Dec-15 2015_12 FBgn0025473 qkr58E-4 quaking related 58E-4 http://flybase.net/reports/FBgn0025473.html gene qrk58E-4 16-Dec-15 2015_12 FBgn0016691 ATPsynO "ATP synthase, oligomycin sensitivity conferring protein" http://flybase.net/reports/FBgn0016691.html protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism" "0015992=proton transport, 0015986=ATP synthesis coupled proton transport" "0005756=mitochondrial proton-transporting ATP synthase, central stalk, 0005811=lipid particle, 0005739=mitochondrion" "ATPO_DROME, ATPO, ATP synthase OSCP, Oscp, OLIGOMYCIN SENSITIVITY CONFERRING PROTEIN, Oligimycin sensitive-conferring protein, Oligomycin sensitivity-conferring protein, oligomycin sensitivity conferring protein precursor, ATP synthase oligomycin sensitivity conferral protein, OSCP, F0/F1 ATP synthase OSCP, CG4307" "IPR026015=F1F0 ATP synthase OSCP/delta subunit, N-terminal domain, IPR000711=ATPase, OSCP/delta subunit" CG4307 16-Dec-15 2015_12 ENSDARG00000001788(atp5o) YDR298C(ATP5) WBGene00000230(atp-3) ENSXETG00000014198(atp5o) "ENSMUSG00000022956(Atp5o),ENSMUSG00000042962(Gm5436)" ENSG00000159186 "lethal,RU486 conditional,developmental rate defective,female sterile,short lived,male,female,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0001520 l(1)11Ad lethal (1) 11Ad http://flybase.net/reports/FBgn0001520.html gene "A4, l(1)VA213" 16-Dec-15 2015_12 "lethal,recessive" FBgn0010872 l(3)05652 lethal (3) 05652 http://flybase.net/reports/FBgn0010872.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive,visible" wing FBgn0004974 NucIII Nuclease III http://flybase.net/reports/FBgn0004974.html gene "0004519=endonuclease activity, 0004527=exonuclease activity, 0004530=deoxyribonuclease I activity, 0004540=ribonuclease activity, 0004536=deoxyribonuclease activity" 16-Dec-15 2015_12 FBgn0039650 Mesh1 Metazoan SpoT homolog-1 http://flybase.net/reports/FBgn0039650.html protein_coding_gene "0008893=guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity" "0042594=response to starvation, 0015971=guanosine tetraphosphate catabolic process" "metazoan SpoT homolog-1, CG11900, Q9VAM9" IPR003607=HD/PDEase domain CG11900 16-Dec-15 2015_12 ENSDARG00000020473(hddc3) WBGene00014148(ZK909.3) ENSXETG00000009763(TGas060e07.1) ENSMUSG00000030532(Hddc3) ENSG00000184508(HDDC3) "viable,small body,stress response defective" FBgn0261515 CG10485 http://flybase.net/reports/FBgn0261515.html FBgn0034969 protein_coding_gene 16-Dec-15 2015_12 FBgn0024150 Ac78C Adenylyl cyclase 78C http://flybase.net/reports/FBgn0024150.html FBgn0040639 protein_coding_gene 0004016=adenylate cyclase activity "0035556=intracellular signal transduction, 0006171=cAMP biosynthetic process, 0010353=response to trehalose, 0009744=response to sucrose, 0031000=response to caffeine, 0001582=detection of chemical stimulus involved in sensory perception of sweet taste" 0005886=plasma membrane "Adenylyl cyclase, AC78C, CG10554, unnamed, DAC78C, DAC78C-s, AC 78C, CG10564" "IPR009398=Adenylate cyclase, conserved domain, IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787=Nucleotide cyclase" CG10564 16-Dec-15 2015_12 "ENSDARG00000031783(adcy8),ENSDARG00000032838" ENSMUSG00000022376(Adcy8) ENSG00000155897(ADCY8) " embryonic stage | stage 7-8 , embryonic stage | >= 8 hr , embryonic stage | 2-4 hr , adult stage , embryonic stage | late , larval stage , embryonic stage | stage 4-8 " " anterior transverse furrow

,

ubiquitous , cephalic furrow

, posterior transverse furrow

" chemosensitive behavior defective FBgn0260114 2L4105 http://flybase.net/reports/FBgn0260114.html gene 16-Dec-15 2015_12 "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0266690 CR45180 http://flybase.net/reports/FBgn0266690.html non_protein_coding_gene CR45180 16-Dec-15 2015_12 FBgn0263944 BG00472 http://flybase.net/reports/FBgn0263944.html gene 16-Dec-15 2015_12 "starvation stress response defective,temperature response defective,gravitaxis defective,long lived,male limited" FBgn0050077 Blos1 "Biogenesis of lysosome-related organelles complex 1, subunit 1" http://flybase.net/reports/FBgn0050077.html FBgn0033944 protein_coding_gene 0005515=protein binding "0008355=olfactory learning, 0048489=synaptic vesicle transport, 0050808=synapse organization, 0007274=neuromuscular synaptic transmission, 0008057=eye pigment granule organization" 0031083=BLOC-1 complex "BLOS1, blos1, NP_725401, CG30077, BLOC-1 subunit 1, CG10127" IPR009395=Biogenesis of lysosome-related organelles complex 1 subunit 1 CG30077 16-Dec-15 2015_12 ENSDARG00000014171(LOC556597) WBGene00011872(T20G5.10) ENSXETG00000017483(BLOC1S1) ENSMUSG00000025349(Bloc1s1) ENSG00000135441(BLOC1S1) "viable,fertile,eye color defective,recessive,neurophysiology defective,courtship behavior defective,male,hyperactive" photoreceptor cell pigment granule FBgn0011975 tRNA:S4:12Ea transfer RNA:ser4:12Ea http://flybase.net/reports/FBgn0011975.html "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052621, FBgn0060063" tRNA_gene "0033408=UCG codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "CR32621, transfer RNA:ser, Ser-tRNA-4, chrX.trna6-SerCGA, tRNA:ser4:12Ea, tRNA:S4, unnamed, Ser tRNA[Ser], tRNA:S, AE002593.trna2-SerCGA, tRNA:ser, transfer RNA:ser4, tRNA:S:CGA:AE002593-a, 444-1, tRNA[[Ser]], tRNA:ser4, tRNA[Ser], tRNA-Ser" CR32621 16-Dec-15 2015_12 FBgn0069220 gl(2R)62-37 gl(2R)62-37 http://flybase.net/reports/FBgn0069220.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal,recessive,germline clone,non-rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0053506 CG33506 http://flybase.net/reports/FBgn0053506.html FBgn0033974 protein_coding_gene CG10220 IPR026620=Transmembrane protein 177 CG33506 16-Dec-15 2015_12 ENSDARG00000031900(LOC100329996) ENSXETG00000027285(TMEM177) ENSMUSG00000036975(Tmem177) ENSG00000144120(TMEM177) viable FBgn0015526 pdg pigment cell degeneration http://flybase.net/reports/FBgn0015526.html gene 16-Dec-15 2015_12 FBgn0263533 mir-4973 mir-4973 stem loop http://flybase.net/reports/FBgn0263533.html miRNA_gene "dme-mir-4973, CR43518" CR43518 16-Dec-15 2015_12 FBgn0051576 tRNA:CR31576 transfer RNA:CR31576 http://flybase.net/reports/FBgn0051576.html FBgn0060284 tRNA_gene 0033453=GCU codon-amino acid adaptor activity 0006412=translation 0005829=cytosol "CR31576, tRNA[[Ala]], AE002708.trna17-AlaAGC, tRNA:A:AGC:AE002708-e, chr3R.trna23-AlaAGC" CR31576 16-Dec-15 2015_12 FBgn0038890 CG7956 http://flybase.net/reports/FBgn0038890.html protein_coding_gene 0042578=phosphoric ester hydrolase activity "IPR002013=SAC domain, IPR022158=Inositol phosphatase" CG7956 16-Dec-15 2015_12 ENSG00000198825(INPP5F) viable FBgn0085454 CG34425 http://flybase.net/reports/FBgn0085454.html "FBan0012584, FBgn0084028, FBgn0037257, FBan0041467" protein_coding_gene "CG41467, CG12584" CG34425 16-Dec-15 2015_12 FBgn0037574 Coq2 Coenzyme Q biosynthesis protein 2 http://flybase.net/reports/FBgn0037574.html protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0008412=4-hydroxybenzoate octaprenyltransferase activity" "0006360=transcription from RNA polymerase I promoter, 0006743=ubiquinone metabolic process, 0050830=defense response to Gram-positive bacterium, 0050829=defense response to Gram-negative bacterium, 0008340=determination of adult lifespan, 0006744=ubiquinone biosynthetic process, 0050832=defense response to fungus, 0048009=insulin-like growth factor receptor signaling pathway" "0005743=mitochondrial inner membrane, 0016021=integral component of membrane, 0005666=DNA-directed RNA polymerase III complex, 0005736=DNA-directed RNA polymerase I complex" "CG9613, COQ2, small boy, coq2, sbo, coenzyme Q biosynthesis protein 2" "IPR000537=UbiA prenyltransferase family, IPR030470=UbiA prenyltransferase conserved site, IPR006370=4-hydroxybenzoate polyprenyltransferase" CG9613 16-Dec-15 2015_12 ENSDARG00000059510(zgc:162600) YNR041C(COQ2) WBGene00000762(coq-2) ENSXETG00000017968(COQ2) ENSMUSG00000029319(Coq2) ENSG00000173085(COQ2) "developmental rate defective,small body,long lived,dominant,locomotor rhythm defective,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,short lived,visible,somatic clone,immune response defective,viable" "eye,somatic clone,eye disc,trichogen cell" DRSC16516 I -1.524945042 0.318123817 0.30773614 0.429396918 1.231857689 -0.094780411 FBgn0034660 lox2 lysyl oxidase-like 2 http://flybase.net/reports/FBgn0034660.html protein_coding_gene "0005044=scavenger receptor activity, 0005507=copper ion binding, 0004720=protein-lysine 6-oxidase activity" "0007155=cell adhesion, 0006464=cellular protein modification process, 0055114=oxidation-reduction process" 0016020=membrane "dmlox-2, Dmloxl-2, CG4402" "IPR017448=SRCR-like domain, IPR001695=Lysyl oxidase, IPR001190=SRCR domain" CG4402 16-Dec-15 2015_12 "ENSDARG00000044074(loxl2b),ENSDARG00000044010(loxl2a),ENSDARG00000039563(loxl3),ENSDARG00000025089" "ENSXETG00000015828(LOXL4),ENSXETG00000007773(LOXL2)" "ENSMUSG00000000693(Loxl3),ENSMUSG00000034205(Loxl2),ENSMUSG00000025185(Loxl4)" "ENSG00000134013(LOXL2),ENSG00000115318(LOXL3),ENSG00000138131(LOXL4)" adult stage organism

viable FBgn0047135 CG32276 http://flybase.net/reports/FBgn0047135.html FBgn0052276 protein_coding_gene 0006464=cellular protein modification process "0005840=ribosome, 0005783=endoplasmic reticulum" BcDNA:RE27904 IPR010580=Stress-associated endoplasmic reticulum protein CG32276 16-Dec-15 2015_12 "ENSDARG00000068699(serp2),ENSDARG00000025493(zgc:56419),ENSDARG00000039008(zgc:85858)" "WBGene00020374(T09A12.5),WBGene00010337(F59F4.2)" "ENSXETG00000026808(SERP2),ENSXETG00000018832(serp1)" "ENSMUSG00000052584(Serp2),ENSMUSG00000027808(Serp1)" "ENSG00000120742(SERP1),ENSG00000151778(SERP2)" "viable,fertile" FBgn0010032 E(Dl)KP420 Enhancer of Delta KP420 http://flybase.net/reports/FBgn0010032.html gene 16-Dec-15 2015_12 FBgn0260277 GSd415 http://flybase.net/reports/FBgn0260277.html gene 16-Dec-15 2015_12 lethal FBgn0065755 l(2)SH0489 lethal (2) SH0489 http://flybase.net/reports/FBgn0065755.html gene l(2)SH2 0489 16-Dec-15 2015_12 "lethal,recessive" FBgn0069989 BG02058 BG02058 http://flybase.net/reports/FBgn0069989.html gene 16-Dec-15 2015_12 stress response defective FBgn0085229 CG34200 http://flybase.net/reports/FBgn0085229.html protein_coding_gene Dm_2R:4171 CG34200 16-Dec-15 2015_12 FBgn0002036 CG10561 http://flybase.net/reports/FBgn0002036.html "FBgn0026744, FBgn0026745, FBgn0043051" protein_coding_gene 0016491=oxidoreductase activity 0055114=oxidation-reduction process 0005737=cytoplasm "TU37C1, anon-37Cd, TuC1, ORF2, anon-37Cb, Cs, unnamed, ORF1, TU37C2, anon-37Cc, cs, lethal(2)37Cs, ORF3, C2, anon-37Cs, transcription unit 37C2, l(2)37Cs, transcription unit No. 2" IPR002937=Amine oxidase CG10561 16-Dec-15 2015_12 " adult stage , adult stage | female , embryonic stage , larval stage | third instar , adult stage | male " " ovary

, adult head

, adult thorax

, adult abdomen

, testis

" "viable,fertile" FBgn0065348 l(2)SH1810 lethal (2) SH1810 http://flybase.net/reports/FBgn0065348.html gene l(2)SH2 1810 16-Dec-15 2015_12 "lethal,recessive" FBgn0040125 l(2)23CDc lethal (2) 23CDc http://flybase.net/reports/FBgn0040125.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0085668 CG41524 http://flybase.net/reports/FBgn0085668.html FBan0041524 protein_coding_gene 16-Dec-15 2015_12 FBgn0259521 B2002 http://flybase.net/reports/FBgn0259521.html gene 16-Dec-15 2015_12 visible "tarsal segment,arista" FBgn0025470 qkr58E-7 quaking related 58E-7 http://flybase.net/reports/FBgn0025470.html gene qrk58E-7 16-Dec-15 2015_12 FBgn0061132 l(3)S002302 lethal (3) S002302 http://flybase.net/reports/FBgn0061132.html "FBgn0061022, FBgn0061083, FBgn0061106" gene "0123/11, l(3)S008136, 0023/02, 0252/47, 0081/36, l(3)S012311, l(3)S025247" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0082368 EP3367 EP3367 http://flybase.net/reports/FBgn0082368.html gene 16-Dec-15 2015_12 "germline cell,male" FBgn0034426 CG10476 http://flybase.net/reports/FBgn0034426.html protein_coding_gene IPR016181=Acyl-CoA N-acyltransferase CG10476 16-Dec-15 2015_12 FBgn0267191 CR45631 http://flybase.net/reports/FBgn0267191.html non_protein_coding_gene CR45631 16-Dec-15 2015_12 FBgn0281840 corset corset http://flybase.net/reports/FBgn0281840.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 FBgn0038290 CG6912 http://flybase.net/reports/FBgn0038290.html "FBgn0044665, FBgn0061871" protein_coding_gene "anon-WO0118547.571, anon-WO0140519.208" CG6912 16-Dec-15 2015_12 viable DRSC16132 EK 0.148206363 0.501328654 -1.898239973 0.219199093 -0.161911793 1.535408873 FBgn0046635 anon-38E.17 anon-38E.17 http://flybase.net/reports/FBgn0046635.html gene 38E.17 16-Dec-15 2015_12 FBgn0050257 tRNA:CR30257 transfer RNA:CR30257 http://flybase.net/reports/FBgn0050257.html "FBgn0011988, FBgn0060034" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033439=ACA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "transfer RNA:thr3:47F, tRNA:T:TGT:AE002787-c, tRNA:thr3:47F, chr2R.trna14-ThrTGT, tRNA[Thr][[3]], CR30257, AE002787.trna32-ThrTGT, tRNA[[Thr]], tRNA:T3:47F" CR30257 16-Dec-15 2015_12 FBgn0038095 Cyp304a1 Cyp304a1 http://flybase.net/reports/FBgn0038095.html FBgn0040492 protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0017143=insecticide metabolic process" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "Cyp304A1, CG7241, 304a1, BcDNA:LP06355, CYP304A1-Dm, cytochrome P450" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG7241 16-Dec-15 2015_12 "fertile,viable" DRSC16623 E 0.269554489 -0.466004842 0.256393564 1.938710036 -0.433945256 -0.121090342 FBgn0035552 CG11350 http://flybase.net/reports/FBgn0035552.html protein_coding_gene 0022008=neurogenesis CG1135 "IPR004019=YLP motif, IPR004011=GYR motif" CG11350 16-Dec-15 2015_12 "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08181 K -1.050918125 -0.098297352 -0.159072562 -0.214522969 -1.503847229 1.242225675 FBgn0070044 3R-196-22 3R-196-22 http://flybase.net/reports/FBgn0070044.html gene 0007379=segment specification 16-Dec-15 2015_12 "terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0052420 tRNA:CR32420 transfer RNA:CR32420 http://flybase.net/reports/FBgn0052420.html "FBgn0011995, FBgn0011996, FBgn0060018" tRNA_gene "0033451=GUA codon-amino acid adaptor activity, 0030533=triplet codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA:V3a:64D, transfer RNA:val3a:64D, chr3L.trna20-ValTAC, AE002602.trna14-ValTAC, CR32420, tRNA[Val][[3a]], valine tRNA, tRNA:V:TAC:AE002602-b, tRNA:val3a:64D, tRNA:V3a" CR32420 16-Dec-15 2015_12 FBgn0266912 CR45372 http://flybase.net/reports/FBgn0266912.html non_protein_coding_gene CR45372 16-Dec-15 2015_12 FBgn0083245 EB5 EB5 http://flybase.net/reports/FBgn0083245.html gene 16-Dec-15 2015_12 FBgn0020351 anon-43AB anon-43AB http://flybase.net/reports/FBgn0020351.html gene 555 16-Dec-15 2015_12 FBgn0005633 fln flightin http://flybase.net/reports/FBgn0005633.html FBgn0010036 protein_coding_gene "0008307=structural constituent of muscle, 0097493=structural molecule activity conferring elasticity" "0007527=adult somatic muscle development, 0071688=striated muscle myosin thick filament assembly, 0045214=sarcomere organization, 0014703=oscillatory muscle contraction, 0030241=skeletal muscle myosin thick filament assembly" "0031672=A band, 0043292=contractile fiber, 0005863=striated muscle myosin thick filament" "Ftn, flightin, CG7445, Flightin, Fln, mp27" CG7445 16-Dec-15 2015_12 " pupal stage , adult stage " indirect flight muscle

" adult stage , pupal stage " indirect flight muscle

"flightless,visible,viable,fertile,recessive,flight defective,locomotor behavior defective" "sarcomere, with fln0,M band, with fln0,A band, with fln0,indirect flight muscle,myofibril, with fln0,wing,dorsal medial muscle,dorsal medial muscle & myofibril,dorsal medial muscle & sarcomere,dorsal medial muscle & striated muscle thick filament,dorsal medial muscle & striated muscle thin filament,indirect flight muscle & striated muscle thick filament,indirect flight muscle & sarcomere,indirect flight muscle & Z disc,indirect flight muscle & striated muscle thin filament,indirect flight muscle & myofibril,indirect flight muscle & muscle tendon junction,sarcomere, with flnëÓC44.Act88F,M band, with flnëÓC44.Act88F,A band, with flnëÓC44.Act88F,myofibril, with flnëÓC44.Act88F" FBgn0032265 CG18301 http://flybase.net/reports/FBgn0032265.html protein_coding_gene "0016788=hydrolase activity, acting on ester bonds" "IPR000073=Alpha/beta hydrolase fold-1, IPR029058=Alpha/Beta hydrolase fold, IPR025483=Lipase, eukaryotic" CG18301 16-Dec-15 2015_12 ENSDARG00000018529(lipf) YKL140W(TGL1) ENSXETG00000009273(lipA) "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" viable FBgn0003913 tyw tiny wing http://flybase.net/reports/FBgn0003913.html gene 16-Dec-15 2015_12 partially lethal - majority live "wing,posterior scutellar bristle,macrochaeta,head,thorax" FBgn0261697 tectonic tectonic http://flybase.net/reports/FBgn0261697.html "FBgn0031783, FBan0009227, FBgn0261684" protein_coding_gene 0008589=regulation of smoothened signaling pathway 0005615=extracellular space "CG42731, Tectonic, CG9227" IPR011677=Domain of unknown function DUF1619 CG42731 16-Dec-15 2015_12 FBgn0031929 CG18585 http://flybase.net/reports/FBgn0031929.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR000834=Peptidase M14, carboxypeptidase A, IPR009020=Proteinase inhibitor, propeptide" CG18585 16-Dec-15 2015_12 "ENSDARG00000021339(cpa5),ENSDARG00000030915(cpa1),ENSDARG00000043722(cpa4),ENSDARG00000010146(cpa2)" YHR132C(ECM14) "WBGene00020281(T06A4.1),WBGene00021213(Y18H1A.9)" ENSXETG00000016293() "ENSMUSG00000011463(Cpb1),ENSMUSG00000071553(Cpa2),ENSMUSG00000054446(Cpa1),ENSMUSG00000029788(Cpa5),ENSMUSG00000001865(Cpa3),ENSMUSG00000042501(Cpa6),ENSMUSG00000021999(Cpb2)" "ENSG00000158516(CPA2),ENSG00000091704(CPA1),ENSG00000158525(CPA5),ENSG00000153002(CPB1)" viable FBgn0266153 CR44859 http://flybase.net/reports/FBgn0266153.html non_protein_coding_gene CR44859 16-Dec-15 2015_12 FBgn0005169 l(2)G566 lethal (2) G566 http://flybase.net/reports/FBgn0005169.html gene 16-Dec-15 2015_12 lethal FBgn0004703 l(2)56Fe lethal (2) 56Fe http://flybase.net/reports/FBgn0004703.html gene l(2)56F 16-Dec-15 2015_12 lethal FBgn0069144 mcl(3)Z4141 mcl(3)Z4141 http://flybase.net/reports/FBgn0069144.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0002828 ms(2)E7 male sterile (2) E7 http://flybase.net/reports/FBgn0002828.html gene "ms2.7, ms(2)2.7" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0063405 l(3)CG2 lethal (3) CG2 http://flybase.net/reports/FBgn0063405.html gene Complementation Group 2 16-Dec-15 2015_12 "lethal,recessive" FBgn0023159 Su(mg)1-9 Suppressor of modifier of gypsy 1-9 http://flybase.net/reports/FBgn0023159.html gene 16-Dec-15 2015_12 FBgn0020531 l(3)319.4 lethal (3) 319.4 http://flybase.net/reports/FBgn0020531.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002905 mus308 mutagen-sensitive 308 http://flybase.net/reports/FBgn0002905.html protein_coding_gene "0003677=DNA binding, 0003887=DNA-directed DNA polymerase activity, 0004386=helicase activity, 0005524=ATP binding" "0006261=DNA-dependent DNA replication, 0097681=double-strand break repair via alternative nonhomologous end joining, 0006289=nucleotide-excision repair, 0006281=DNA repair" "Mus308, CG6019, PolQ, 0443/09, DNA polymerase theta, AAF54858, Pol theta, mus-308, POLQ, Nuc3, Nuclease-3, pol theta" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001098=DNA-directed DNA polymerase, family A, palm domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR002298=DNA polymerase A, IPR012337=Ribonuclease H-like domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR003583=Helix-hairpin-helix DNA-binding motif, class 1" CG6019 16-Dec-15 2015_12 WBGene00020964(polq-1) ENSMUSG00000034206(Polq) ENSG00000051341(POLQ) oogenesis stage && adult stage | female ovary

"male sterile,chemical sensitive,DNA repair defective,recessive,visible,radiation sensitive,viable,lethal,female fertile,poor" wing FBgn0263323 CR43404 http://flybase.net/reports/FBgn0263323.html non_protein_coding_gene "lincRNA.89, CG43404" CR43404 16-Dec-15 2015_12 FBgn0037413 Osi5 Osiris 5 http://flybase.net/reports/FBgn0037413.html protein_coding_gene 0005887=integral component of plasma membrane "CG15590, Osiris" IPR012464=Protein of unknown function DUF1676 CG15590 16-Dec-15 2015_12 viable FBgn0040062 yip4 yippee interacting protein 4 http://flybase.net/reports/FBgn0040062.html gene 16-Dec-15 2015_12 FBgn0052396 CG32396 http://flybase.net/reports/FBgn0052396.html FBgn0043453 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0005200=structural constituent of cytoskeleton" "0007017=microtubule-based process, 0051258=protein polymerization" 0005874=microtubule "CG8339, unnamed, CT42364" "IPR008280=Tubulin/FtsZ, C-terminal, IPR017975=Tubulin, conserved site, IPR002453=Beta tubulin, IPR000217=Tubulin, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR013838=Beta tubulin, autoregulation binding site" CG32396 16-Dec-15 2015_12 viable FBgn0038250 CG3505 http://flybase.net/reports/FBgn0038250.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "proPO-AE, SPH9" "IPR022700=Proteinase, regulatory CLIP domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR006604=Disulphide knot CLIP, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG3505 16-Dec-15 2015_12 viable FBgn0010183 tu(2)K tu(2)K http://flybase.net/reports/FBgn0010183.html gene 16-Dec-15 2015_12 FBgn0261709 CR42746 http://flybase.net/reports/FBgn0261709.html non_protein_coding_gene CR42746 16-Dec-15 2015_12 FBgn0062606 Mod(var)1367 Mod(var)1367 http://flybase.net/reports/FBgn0062606.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1367 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0014055 Su(tor)2-399 Su(tor)2-399 http://flybase.net/reports/FBgn0014055.html gene 16-Dec-15 2015_12 FBgn0262191 mir-2497 mir-2497 stem loop http://flybase.net/reports/FBgn0262191.html miRNA_gene "CR42898, dme-mir-2497" CR42898 16-Dec-15 2015_12 viable FBgn0267509 5.8SrRNA-ë¬:CR45849 5.8S ribosomal RNA pseudogene:CR45849 http://flybase.net/reports/FBgn0267509.html pseudogene_attribute CR45849 CR45849 16-Dec-15 2015_12 FBgn0065573 l(2)SH0956 lethal (2) SH0956 http://flybase.net/reports/FBgn0065573.html gene l(2)SH2 0956 16-Dec-15 2015_12 "lethal,recessive" FBgn0015221 Fer2LCH Ferritin 2 light chain homologue http://flybase.net/reports/FBgn0015221.html "FBgn0010705, FBgn0011018, FBgn0011321, FBgn0011490, FBgn0011491, FBgn0026287, FBgn0039763" protein_coding_gene "0008198=ferrous iron binding, 0008199=ferric iron binding" "0009620=response to fungus, 0045475=locomotor rhythm, 0042381=hemolymph coagulation, 0022416=chaeta development, 0097459=iron ion import into cell, 0006879=cellular iron ion homeostasis, 1990461=detoxification of iron ion" "0005794=Golgi apparatus, 0012505=endomembrane system, 0005576=extracellular region, 0008043=intracellular ferritin complex" "Ferritin 2 Light Chain Homologue, ferritin, CG1469, fer2, Fer2LC, Fe2LCH, fer2lch, Ferritin, ferritin light chain, Ferritin-Heavy, l(3)neo63, l(3)07016, FerLCH, 2LCH, Ferritin L, Fer-H, l(3)00035, Ferritin-Light, l(3)neo60, ferritin LCH, anon-EST:ParkEST264, Ferritin 2 light chain, LCH, l(3)j2A3, unnamed, ferritin 2 light chain, l(3)s2083" "IPR012347=Ferritin-related, IPR009078=Ferritin-like superfamily, IPR001519=Ferritin, IPR008331=Ferritin/DPS protein domain, IPR009040=Ferritin- like diiron domain" CG1469 16-Dec-15 2015_12 "lethal,viable,fertile,recessive,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,locomotor rhythm defective,circadian rhythm defective,gravitaxis defective,progressive" DRSC16672 K 0.290855981 -0.32930079 -0.942798565 -0.540428811 -2.349865675 -2.256859738 FBgn0263573 mir-4942 mir-4942 stem loop http://flybase.net/reports/FBgn0263573.html miRNA_gene "dme-mir-4942, CR43558" CR43558 16-Dec-15 2015_12 FBgn0042137 CG18814 http://flybase.net/reports/FBgn0042137.html protein_coding_gene 0004022=alcohol dehydrogenase (NAD) activity "0055114=oxidation-reduction process, 0006066=alcohol metabolic process" "IPR002425=Alcohol dehydrogenase, Drosophila-type, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain, IPR002424=Alcohol dehydrogenase, insect-type" CG18814 16-Dec-15 2015_12 "ENSDARG00000026236(zgc:56585),ENSDARG00000012016(LOC565975)" ENSXETG00000016904(hpgd) ENSMUSG00000031613(Hpgd) ENSG00000164120(HPGD) viable FBgn0051888 tRNA:CR31888 transfer RNA:CR31888 http://flybase.net/reports/FBgn0051888.html "FBgn0011843, FBgn0060260" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033458=GAC codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "tRNA[[Asp]], transfer RNA:asp2:29E, tRNA:D:GTC:AE002690-e, tRNA:D2:29E, chr2L.trna30-AspGTC, tRNA:asp2:29E, AE002690.trna21-AspGTC, CR31888, tRNA[Asp-GTC]" CR31888 16-Dec-15 2015_12 FBgn0062613 Mod(var)1294 Mod(var)1294 http://flybase.net/reports/FBgn0062613.html gene 0006342=chromatin silencing 1294 16-Dec-15 2015_12 "suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0044413 Scim14 Sensitized chromosome inheritance modifier 14 http://flybase.net/reports/FBgn0044413.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0029048 l(1)G0473 lethal (1) G0473 http://flybase.net/reports/FBgn0029048.html gene 16-Dec-15 2015_12 "female sterile,lethal,recessive" FBgn0034121 CG6262 http://flybase.net/reports/FBgn0034121.html protein_coding_gene "0015927=trehalase activity, 0004555=alpha,alpha-trehalase activity" 0005991=trehalose metabolic process "IPR001661=Glycoside hydrolase, family 37, IPR008928=Six-hairpin glycosidase-like" CG6262 16-Dec-15 2015_12 "YDR001C(NTH1),YBR001C(NTH2)" WBGene00006607(tre-1) ENSXETG00000021551(TREH) ENSMUSG00000032098(Treh) ENSG00000118094(TREH) viable FBgn0265579 CG44406 http://flybase.net/reports/FBgn0265579.html protein_coding_gene CG44406 16-Dec-15 2015_12 FBgn0020349 anon-44CDa anon-44CDa http://flybase.net/reports/FBgn0020349.html gene 536 16-Dec-15 2015_12 FBgn0005289 mei-1966 meiotic 1966 http://flybase.net/reports/FBgn0005289.html gene 1966 16-Dec-15 2015_12 "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0026615 4-Oct 4-Oct http://flybase.net/reports/FBgn0026615.html gene "0045177=apical part of cell, 0005737=cytoplasm" 16-Dec-15 2015_12 FBgn0040561 CG14844 http://flybase.net/reports/FBgn0040561.html protein_coding_gene 16-Dec-15 2015_12 FBgn0005663 dodeca dodeca http://flybase.net/reports/FBgn0005663.html repeat_region "Dodeca, dodecasatellite, Dodeca satellite" 16-Dec-15 2015_12 FBgn0266469 nuss http://flybase.net/reports/FBgn0266469.html gene 16-Dec-15 2015_12 "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0085666 CG41521 http://flybase.net/reports/FBgn0085666.html FBan0041521 protein_coding_gene 16-Dec-15 2015_12 FBgn0028210 l(3)S011004 lethal (3) S011004 http://flybase.net/reports/FBgn0028210.html gene 0110/04 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" FBgn0034327 CG14505 http://flybase.net/reports/FBgn0034327.html protein_coding_gene "IPR023231=GSKIP domain, IPR007967=Protein of unknown function DUF727" CG14505 16-Dec-15 2015_12 ENSXETG00000013951(C14orf129) ENSMUSG00000044715(4933433P14Rik) viable FBgn0039694 fig fos intronic gene http://flybase.net/reports/FBgn0039694.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0004721=phosphoprotein phosphatase activity" "0006470=protein dephosphorylation, 0016311=dephosphorylation" "fos-intronic gene, fos intron gene, CG7615" IPR001932=PPM-type phosphatase domain CG7615 16-Dec-15 2015_12 YHR076W(PTC7) "partially lethal - majority die,some die during pupal stage" FBgn0031747 CG9021 http://flybase.net/reports/FBgn0031747.html protein_coding_gene IPR010629=Insect allergen-related CG9021 16-Dec-15 2015_12 viable FBgn0037342 CG2931 http://flybase.net/reports/FBgn0037342.html protein_coding_gene "0000166=nucleotide binding, 0003676=nucleic acid binding, 0003729=mRNA binding" "0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" cg2931 "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG2931 16-Dec-15 2015_12 ENSDARG00000039910(rbm42) WBGene00021901(tag-262) ENSXETG00000017599(TNeu057g23.1) ENSMUSG00000036733(Rbm42) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,tormogen cell,mesothoracic tergum" DRSC12324 K 1.367713832 0.217355838 0.627371263 0.881955292 -1.792911199 -1.485319361 FBgn0036302 sowah sosondowah http://flybase.net/reports/FBgn0036302.html FBgn0064944 protein_coding_gene "Sosondowah, CG10632, BcDNA:GM09162" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG10632 16-Dec-15 2015_12 "ENSMUSG00000045314(Ankrd56),ENSMUSG00000044352(Ankrd43),ENSMUSG00000071286(Ankrd57)" "viable,fertile" DRSC09186 I 1.758314236 -0.161173028 0.784277486 0.200808964 0.924051238 -0.248672762 FBgn0020295 kiwi kiwi http://flybase.net/reports/FBgn0020295.html gene 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces 16-Dec-15 2015_12 "lethal,recessive,visible,somatic clone" "wing,somatic clone,larva" FBgn0001675 l(1)EN12 lethal (1) from Eugene Nonautonomous 12 http://flybase.net/reports/FBgn0001675.html gene 16-Dec-15 2015_12 "lethal,recessive,body color defective" adult cuticle FBgn0060864 l(3)S047324 lethal (3) S047324 http://flybase.net/reports/FBgn0060864.html gene 0473/24 16-Dec-15 2015_12 "lethal,recessive" FBgn0035024 CG11414 http://flybase.net/reports/FBgn0035024.html protein_coding_gene "0008270=zinc ion binding, 0044822=poly(A) RNA binding" 0007067=mitotic nuclear division "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR001841=Zinc finger, RING-type" CG11414 16-Dec-15 2015_12 ENSDARG00000014945(znf598) YDR266C() WBGene00016888(C52E12.1) ENSXETG00000022671(ZNF598) ENSMUSG00000041130(Zfp598) ENSG00000167962(ZNF598) viable FBgn0022229 l(2)k03105 lethal (2) k03105 http://flybase.net/reports/FBgn0022229.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0027157 l(2)T-14.3 lethal (2) T-14.3 http://flybase.net/reports/FBgn0027157.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0003086 Pig1 Pre-intermoult gene 1 http://flybase.net/reports/FBgn0003086.html protein_coding_gene "gland specific gene, unnamed, pig1, gsg, CG10790, Pig-1, EG:96G10.1, Pre-intermolt gene 1" CG10790 16-Dec-15 2015_12 larval stage " embryonic/larval salivary gland

, organism

" viable FBgn0002922 nau nautilus http://flybase.net/reports/FBgn0002922.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0046983=protein dimerization activity" "0016204=determination of muscle attachment site, 0006355=regulation of transcription, DNA-templated, 0007517=muscle organ development, 0007526=larval somatic muscle development, 0016202=regulation of striated muscle tissue development" "0005737=cytoplasm, 0005634=nucleus" "Nautilus, MYOD, Dmyd, MyoD, CG10250, NAU, Mdrf, myogenic determination, Nau" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR002546=Myogenic basic muscle-specific protein" CG10250 16-Dec-15 2015_12 "ENSDARG00000030110(myod1),ENSDARG00000007277(myf5)" "ENSXETG00000014520(myf5),ENSXETG00000001320(myod1)" "ENSMUSG00000009471(Myod1),ENSMUSG00000000435(Myf5)" "ENSG00000129152(MYOD1),ENSG00000111049(MYF5)" " embryonic stage , embryonic stage && larval stage " " somatic mesoderm

{ e bib* } , somatic mesoderm

{ e N* } , larval muscle system

, larval somatic muscle

{ e Dl* } , somatic mesoderm

{ e mam* } , somatic mesoderm

{ e amx* } , somatic mesoderm

{ e Nj* } , somatic mesoderm

{ e neur* } , somatic mesoderm

, somatic mesoderm

{ e E(spl)* } " " embryonic stage | stage >=11 , embryonic stage | stage >=14 " "

segmentally repeated , somatic muscle &&of telson

, pharyngeal muscle

, larval muscle system

, abdominal 1 ventral longitudinal muscle 1

, abdominal 1 ventral acute muscle 2

, abdominal 1 ventral acute muscle 1

, ventral oblique muscle

, abdominal 1--7 ventral oblique muscle 5

, abdominal 1--7 ventral oblique muscle 4

, anterior spiracle retractor muscle

, abdominal 2--7 ventral oblique muscle 6

" "female sterile,viable,sterile,recessive,lethal,flightless,locomotor behavior defective,partially" "A1-7 dorsal oblique muscle 4,abdominal 1 dorsal acute muscle 3,embryonic/larval somatic muscle,presumptive embryonic/larval muscle system,germline clone,A1-7 dorsal acute muscle 3,A1-7 dorsal oblique muscle 3,myoblast,cardioblast,somatic mesoderm,egg,egg chamber,midgut constriction" FBgn0065443 l(2)SH1452 lethal (2) SH1452 http://flybase.net/reports/FBgn0065443.html gene l(2)SH2 1452 16-Dec-15 2015_12 "lethal,recessive" FBgn0024516 l(3)j14E7 lethal (3) j14E7 http://flybase.net/reports/FBgn0024516.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0016646 ER3-4 ER3-4 http://flybase.net/reports/FBgn0016646.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265837 CR44626 http://flybase.net/reports/FBgn0265837.html non_protein_coding_gene CR44626 16-Dec-15 2015_12 FBgn0003500 srb smaller body http://flybase.net/reports/FBgn0003500.html gene "sby-62, small body 62" 16-Dec-15 2015_12 "viable,female fertile,reduced,size defective" macrochaeta FBgn0037276 CG17387 http://flybase.net/reports/FBgn0037276.html protein_coding_gene CG17387 16-Dec-15 2015_12 ENSDARG00000016485 ENSXETG00000019437(CCDC39) ENSMUSG00000027676(Ccdc39) ENSG00000145075(CCDC39) viable FBgn0262444 mir-1013 mir-1013 stem loop http://flybase.net/reports/FBgn0262444.html "FBgn0250809, FBgn0262303" miRNA_gene "dme-mir-1013, CR43010, miR-1013" CR43010 16-Dec-15 2015_12 viable FBgn0002829 ms(2)E8 male sterile (2) E8 http://flybase.net/reports/FBgn0002829.html gene "ms(2)2.8, ms2.8" 16-Dec-15 2015_12 "male sterile,recessive" FBgn0035480 CG14984 http://flybase.net/reports/FBgn0035480.html protein_coding_gene CG14984 16-Dec-15 2015_12 viable FBgn0002792 MRF Male recombination factor http://flybase.net/reports/FBgn0002792.html gene "Male Recombination, Mister, MRF, MR" 16-Dec-15 2015_12 FBgn0001530 l(1)11Ef lethal (1) 11Ef http://flybase.net/reports/FBgn0001530.html gene 16-Dec-15 2015_12 lethal FBgn0035393 CG16753 http://flybase.net/reports/FBgn0035393.html protein_coding_gene CG16753 16-Dec-15 2015_12 ENSDARG00000071500(si:dkeyp-84a8.8) FBgn0014312 l(3)ry107 lethal (3) ry107 http://flybase.net/reports/FBgn0014312.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0264631 black-hole black hole http://flybase.net/reports/FBgn0264631.html gene "0060439=trachea morphogenesis, 0007430=terminal branching, open tracheal system" 16-Dec-15 2015_12 "embryonic/larval tracheal system,eye,somatic clone,terminal tracheal cell" FBgn0015960 l(2)40Aa lethal (2) 40Aa http://flybase.net/reports/FBgn0015960.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0025497 l(3)73Bg lethal (3) 73Bg http://flybase.net/reports/FBgn0025497.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043572 S(faf)86 S(faf)86 http://flybase.net/reports/FBgn0043572.html gene 16-Dec-15 2015_12 "viable,wild-type" FBgn0263564 mir-4914 mir-4914 stem loop http://flybase.net/reports/FBgn0263564.html miRNA_gene "dme-mir-4914, CR43549" CR43549 16-Dec-15 2015_12 FBgn0030719 eIF5 eIF5 http://flybase.net/reports/FBgn0030719.html FBgn0025193 protein_coding_gene 0003743=translation initiation factor activity "0006413=translational initiation, 0022008=neurogenesis" 0005829=cytosol "anon-fast-evolving-3C6, CG9177, EIf5, unnamed, anon-EST:fe3C6" "IPR016024=Armadillo-type fold, IPR016189=Translation initiation factor IF2/IF5, N-terminal, IPR016190=Translation initiation factor IF2/IF5, zinc-binding, IPR003307=W2 domain, IPR016021=MIF4G-like domain, IPR002735=Translation initiation factor IF2/IF5" CG9177 16-Dec-15 2015_12 ENSDARG00000003681(eif5) YPR041W(TIF5) WBGene00016496(C37C3.2) ENSXETG00000012766(eif5) ENSMUSG00000021282(Eif5) ENSG00000100664(EIF5) "lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective" "ganglion mother cell,embryonic/larval neuroblast" FBgn0065832 l(2)SH0348 lethal (2) SH0348 http://flybase.net/reports/FBgn0065832.html gene l(2)SH2 0348 16-Dec-15 2015_12 "lethal,recessive" FBgn0263601 mib1 mind bomb 1 http://flybase.net/reports/FBgn0263601.html "FBgn0036558, FBgn0016899, FBgn0005535" protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0061630=ubiquitin protein ligase activity, 0004842=ubiquitin-protein transferase activity" "0046331=lateral inhibition, 0045807=positive regulation of endocytosis, 0007476=imaginal disc-derived wing morphogenesis, 0045747=positive regulation of Notch signaling pathway, 0000209=protein polyubiquitination, 0007219=Notch signaling pathway, 0006897=endocytosis, 0008587=imaginal disc-derived wing margin morphogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0048749=compound eye development, 0001745=compound eye morphogenesis, 0008104=protein localization, 0008593=regulation of Notch signaling pathway, 0016567=protein ubiquitination, 0007423=sensory organ development" "0005737=cytoplasm, 0045179=apical cortex" "Mind bomb 1, Mib1, dmib1, MIB1, l(3)72Db, Mib, CG5841, lethal (3) 72Db, D-mib, mindbomb1, Mind bomb1, mind bomb1, Dmib, l(3)72CDa, Mindbomb1, mib, Mind bomb-1, mib1/2, lethal (3) 72CDa, Mindbomb, D-mib1, Mind Bomb, mind-bomb, Mindbomb 1" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR010606=Mib-herc2, IPR000433=Zinc finger, ZZ-type, IPR001841=Zinc finger, RING-type" CG5841 16-Dec-15 2015_12 ENSDARG00000008424 WBGene00012933(Y47D3A.22) ENSXETG00000003146(MIB1) ENSMUSG00000024294(Mib1) ENSG00000101752(MIB1) DRSC10550 I 1.116112117 1.524076813 1.119387857 -0.048132077 -0.040790088 -0.247937495 FBgn0015445 l(1)7Do lethal (1) 7Do http://flybase.net/reports/FBgn0015445.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060684 l(3)S075901 lethal (3) S075901 http://flybase.net/reports/FBgn0060684.html gene 0759/01 16-Dec-15 2015_12 "lethal,recessive" FBgn0014240 l(2)32Aa lethal (2) 32Aa http://flybase.net/reports/FBgn0014240.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0259967 Sfp53D Seminal fluid protein 53D http://flybase.net/reports/FBgn0259967.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "HDC06796, Seminal fluid protein 53D, CG42477" CG42477 16-Dec-15 2015_12 FBgn0032435 Oatp33Eb Organic anion transporting polypeptide 33Eb http://flybase.net/reports/FBgn0032435.html protein_coding_gene "0015347=sodium-independent organic anion transmembrane transporter activity, 0008514=organic anion transmembrane transporter activity" "0006810=transport, 0015711=organic anion transport" 0016020=membrane "oatp 33Eb, CG6417" "IPR020846=Major facilitator superfamily domain, IPR002350=Kazal domain, IPR004156=Organic anion transporter polypeptide OATP" CG6417 16-Dec-15 2015_12 viable FBgn0065130 l(3)SH133 lethal (3) SH133 http://flybase.net/reports/FBgn0065130.html gene l(2)SH3 133 16-Dec-15 2015_12 "lethal,recessive" FBgn0015799 Rbf Retinoblastoma-family protein http://flybase.net/reports/FBgn0015799.html protein_coding_gene "0008134=transcription factor binding, 0005515=protein binding, 0044212=transcription regulatory region DNA binding, 0003677=DNA binding, 0001012=RNA polymerase II regulatory region DNA binding" "1900117=regulation of execution phase of apoptosis, 0010629=negative regulation of gene expression, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0010941=regulation of cell death, 0007307=eggshell chorion gene amplification, 0051726=regulation of cell cycle, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0042023=DNA endoreduplication, 0043066=negative regulation of apoptotic process, 0008285=negative regulation of cell proliferation, 0042127=regulation of cell proliferation, 0007095=mitotic G2 DNA damage checkpoint, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0007113=endomitotic cell cycle, 0008156=negative regulation of DNA replication, 0042594=response to starvation, 0051101=regulation of DNA binding, 0008361=regulation of cell size" "0031523=Myb complex, 0005634=nucleus, 0000785=chromatin, 0035189=Rb-E2F complex" "retinoblastoma factor-1, Rbf1, rbf, retinoblastoma factor, FBF, Rb, rbf1, CG7413, RbF, rb, RBF1, Rb1, dRBF, retinoblastoma-family protein, pRb, EG:34F3.3, Retinoblastoma, retinoblastoma family protein 1, RB, retinoblastoma, retinoblastoma-family homolog, RBF" "IPR024599=Retinoblastoma-associated protein, N-terminal, IPR002720=Retinoblastoma-associated protein, A-box, IPR028309=Retinoblastoma protein family, IPR002719=Retinoblastoma-associated protein, B-box, IPR013763=Cyclin-like" CG7413 16-Dec-15 2015_12 "ENSDARG00000045636,ENSDARG00000008141(rbl1)" WBGene00003020(lin-35) "ENSXETG00000000346(RBL2),ENSXETG00000007414(RBL1)" "ENSMUSG00000027641(Rbl1),ENSMUSG00000031666(Rbl2)" "ENSG00000080839(RBL1),ENSG00000103479(RBL2)" "viable,fertile,sterile,increased cell death,recessive,somatic clone,cell growth defective,increased cell number,visible,wild-type,lethal,germline clone,rescuable maternal effect,some die during second instar larval stage,some die during third instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage,mitotic cell cycle defective,neuroanatomy defective,decreased cell number,developmental rate defective,immune response defective,partially" "chorion,follicle cell & cell cycle,S phase | ectopic & eye disc | posterior,eye disc,eye,follicle cell,mitotic cell cycle,somatic clone,eye disc anterior to the morphogenetic furrow,morphogenetic furrow,ommatidium,eye disc posterior to the morphogenetic furrow,interommatidial bristle,pigment cell,ectopic,scutellar bristle,embryonic epidermis,embryonic/larval midgut primordium,embryonic epidermis & S phase | germ-line clone,S phase | ectopic,embryonic epidermis & S phase,wing disc,cone cell,eye photoreceptor cell,wing margin,mitotic cell cycle | somatic clone,submarginal cell,anterior crossvein,wing,posterior compartment,abdomen,chaeta,mesothoracic tergum" FBgn0040618 CG14063 http://flybase.net/reports/FBgn0040618.html protein_coding_gene 16-Dec-15 2015_12 FBgn0010656 l(2)09639 lethal (2) 09639 http://flybase.net/reports/FBgn0010656.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0023153 Su(mg)2-6 Suppressor of modifier of gypsy 2-6 http://flybase.net/reports/FBgn0023153.html gene 16-Dec-15 2015_12 FBgn0031456 Trn-SR Transportin-Serine/Arginine rich http://flybase.net/reports/FBgn0031456.html FBgn0025293 protein_coding_gene "0005515=protein binding, 0008536=Ran GTPase binding" "0006606=protein import into nucleus, 0022008=neurogenesis, 0035048=splicing factor protein import into nucleus, 0048024=regulation of mRNA splicing, via spliceosome, 0006406=mRNA export from nucleus" "0005634=nucleus, 0005737=cytoplasm" "transportin, anon-EST:Posey294, CG2848, Transportin-serine/arginine rich, dTRN-SR, TNPO3" "IPR013598=Exportin-1/Importin-beta-like, IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG2848 16-Dec-15 2015_12 ENSDARG00000045680(tnpo3) YOR160W(MTR10) WBGene00006647(tsr-1) ENSXETG00000015009(TNPO3) ENSMUSG00000012535(Tnpo3) ENSG00000064419(TNPO3) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" FBgn0026092 E(ltv)319 E(ltv)319 http://flybase.net/reports/FBgn0026092.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0050081 Ir51b Ionotropic receptor 51b http://flybase.net/reports/FBgn0050081.html protein_coding_gene 0015276=ligand-gated ion channel activity 0009593=detection of chemical stimulus 0016021=integral component of membrane "ionotropic receptor 51b, DmelIR51b, CG30081, IR51b" CG30081 16-Dec-15 2015_12 viable FBgn0031090 Rab35 Rab35 http://flybase.net/reports/FBgn0031090.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0032482=Rab protein signal transduction, 1990182=exosomal secretion, 0016192=vesicle-mediated transport, 0015031=protein transport, 0000281=mitotic cytokinesis, 0006909=phagocytosis" "0031982=vesicle, 0005811=lipid particle, 0045202=synapse, 0043025=neuronal cell body, 0005886=plasma membrane" "Q95RH7, rab35, CG9575, DRab35, dRab35, DmRab35" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type" CG9575 16-Dec-15 2015_12 "ENSDARG00000058425(rab35),ENSDARG00000063142,ENSDARG00000037967(LOC100003902)" WBGene00004284(rab-35) "ENSXETG00000026943(rab35),ENSXETG00000011370(BC061274.1)" ENSMUSG00000029518(Rab35) ENSG00000111737(RAB35) "neurophysiology defective,partially lethal - majority die" embryonic/larval neuromuscular junction FBgn0062653 EP3714 EP3714 http://flybase.net/reports/FBgn0062653.html gene EP(3)3714 16-Dec-15 2015_12 FBgn0023119 anon-10Ao anon-10Ao http://flybase.net/reports/FBgn0023119.html gene 7 16-Dec-15 2015_12 FBgn0011705 rost rolling stone http://flybase.net/reports/FBgn0011705.html protein_coding_gene "0007520=myoblast fusion, 0007519=skeletal muscle tissue development" 0016020=membrane CG9552 CG9552 16-Dec-15 2015_12 " embryonic stage | stage 16-17 , embryonic stage | 0-4 hr , embryonic stage | early , adult stage && oogenesis stage , embryonic stage | stage 12 , embryonic stage | stage 13-17 , embryonic stage , embryonic stage | >=8-12 hr , adult stage , embryonic stage | stage 12-14 " " gonad | restricted

, nurse cell

, embryonic head

, embryonic central nervous system | restricted

, muscle system | restricted

, embryonic brain | restricted

, mesoderm

segmentally repeated " "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "somatic muscle,myoblast,segment border muscle,ectopic,embryonic/larval somatic muscle,ventral,lateral longitudinal muscle 1,lateral oblique muscle 1" FBgn0260454 CG17139 http://flybase.net/reports/FBgn0260454.html "FBgn0032307, FBgn0032306, FBgn0051722" protein_coding_gene "0008308=voltage-gated anion channel activity, 0015267=channel activity" "0055085=transmembrane transport, 0006820=anion transport" 0005741=mitochondrial outer membrane "CG31722, CG31722-A" "IPR023614=Porin domain, IPR027246=Eukaryotic porin/Tom40" CG17139 16-Dec-15 2015_12 FBgn0013597 l(3)B14.1M3 lethal (3) B14.1M3 http://flybase.net/reports/FBgn0013597.html gene 16-Dec-15 2015_12 lethal FBgn0045035 tefu telomere fusion http://flybase.net/reports/FBgn0045035.html FBgn0038308 protein_coding_gene "0004672=protein kinase activity, 0035173=histone kinase activity" "0031000=response to caffeine, 0016233=telomere capping, 0045824=negative regulation of innate immune response, 0051276=chromosome organization, 0030717=karyosome formation, 0006348=chromatin silencing at telomere, 0000706=meiotic DNA double-strand break processing, 1990164=histone H2A phosphorylation, 0006468=protein phosphorylation, 0034351=negative regulation of glial cell apoptotic process, 0000723=telomere maintenance, 0016310=phosphorylation, 0007095=mitotic G2 DNA damage checkpoint, 1901215=negative regulation of neuron death, 0045494=photoreceptor cell maintenance, 0007093=mitotic cell cycle checkpoint" 0005634=nucleus "tef, ataxia telengiesctasia mutated, ataxia telangiectasia mutated, ATM, atm/tefu, Drosophila ATM, CG6535, Atm, unnamed, atm, ataxia-telangiectasia mutated, Tefu, A-T mutated, dATM" "IPR014009=PIK-related kinase, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR011009=Protein kinase-like domain, IPR003152=FATC domain" CG6535 16-Dec-15 2015_12 ENSMUSG00000034218(Atm) ENSG00000149311(ATM) "neuroanatomy defective,increased cell number,decreased cell death,increased cell death,temperature conditional,locomotor behavior defective,gravitaxis defective,short lived,long lived,visible,somatic clone,DNA repair defective,cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,mitotic cell cycle defective,lethal - all die during pupal stage,female sterile,radiation sensitive,lethal - all die before end of P-stage,majority die during pharate adult stage,lethal,maternal effect,lethal - all die during embryonic stage,non-rescuable maternal effect,viable,heat sensitive,female,male,semidominant,conditional,dominant,progressive,radiation resistant,cell non-autonomous" "rhabdomere of eye photoreceptor cell,eye disc posterior to the morphogenetic furrow | third instar larval stage,eye photoreceptor cell | third instar larval stage,eye,eye photoreceptor cell,temperature conditional,neuropil,lamina,neuron,glial cell,optic lobe,antenna,wing,leg,chaeta,somatic clone,embryonic/larval neuroblast,metaphase & condensed nuclear chromosome,anaphase & condensed nuclear chromosome,chromosome, telomeric region,macrochaeta,wing disc,eye disc,mitosis & nuclear chromosome,cleavage nucleus,germline clone,maternal effect,spindle | germline clone | maternal effect,chorion | germline clone | maternal effect,dorsal appendage,mitosis & nuclear chromosome | maternal effect | germ-line clone,condensed chromosome,chromosome, telomeric region | embryonic stage | maternal effect, with tefuZIII-5190,ommatidium,interommatidial bristle,chromosome & neuroblast | third instar larval stage 2,heat sensitive,adult thorax & chaeta | conditional tsPG4),eye-antennal disc,anterior,karyosome,cell non-autonomous,chromosome, telomeric region | embryonic stage | maternal effect, with tefustg" FBgn0267936 CR46216 http://flybase.net/reports/FBgn0267936.html non_protein_coding_gene lincRNA.620 CR46216 16-Dec-15 2015_12 FBgn0024177 zpg zero population growth http://flybase.net/reports/FBgn0024177.html FBgn0035706 protein_coding_gene 0005243=gap junction channel activity "0007281=germ cell development, 0010496=intercellular transport" "0005921=gap junction, 0016021=integral component of membrane, 0005886=plasma membrane" "Inx4, inx-4, Innexin-4, CG10125, Dm-inx4, inx4, FBpp0076692, Innexin 4, Zpg, innexin 4" IPR000990=Innexin CG10125 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" " embryonic stage | stage 13 , embryonic stage | blastoderm , adult stage , adult stage | male " " germline cell

, pole cell

, spermatogonium

" " adult stage | female && oogenesis stage | stage S6-7 , larval stage | third instar , adult stage " " egg chamber

, spermatogonium

, germarium

, ovariole | stage 8-9

, primary spermatocyte cyst

" "lethal,recessive,viable,male sterile,female sterile" "ovary,female germline cell,testis,male germline stem cell,primary gonial cell,spermatogonium,hub cell,supernumerary,cyst cell,egg chamber,female germline stem cell,germ cell & germarium,cystoblast,cystocyte,nurse cell fusome" FBgn0030725 CG8958 http://flybase.net/reports/FBgn0030725.html protein_coding_gene "IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like, IPR014710=RmlC-like jelly roll fold" CG8958 16-Dec-15 2015_12 ENSMUSG00000038085 ENSG00000149646(C20orf152) viable FBgn0053463 CG33463 http://flybase.net/reports/FBgn0053463.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33463 16-Dec-15 2015_12 DRSC22915 K 0.106040764 -0.202488313 0.613337695 -0.304039787 -1.15425978 1.570047847 FBgn0261805 CG42751 http://flybase.net/reports/FBgn0261805.html protein_coding_gene CG42751 16-Dec-15 2015_12 FBgn0267050 CG45494 http://flybase.net/reports/FBgn0267050.html protein_coding_gene CG45494 16-Dec-15 2015_12 FBgn0038657 CG14293 http://flybase.net/reports/FBgn0038657.html protein_coding_gene 16-Dec-15 2015_12 FBgn0019953 NucU NucU http://flybase.net/reports/FBgn0019953.html gene 0004536=deoxyribonuclease activity 0006308=DNA catabolic process unnamed 16-Dec-15 2015_12 FBgn0033247 Nup44A Nucleoporin at 44A http://flybase.net/reports/FBgn0033247.html protein_coding_gene 0017056=structural constituent of nuclear pore "0007293=germarium-derived egg chamber formation, 1903432=regulation of TORC1 signaling, 0010507=negative regulation of autophagy, 0048477=oogenesis, 0007184=SMAD protein import into nucleus, 0007346=regulation of mitotic cell cycle, 0051445=regulation of meiotic cell cycle" "0005643=nuclear pore, 0005635=nuclear envelope, 0044754=autolysosome, 0043234=protein complex, 0005764=lysosome, 0035859=Seh1-associated complex" "nup44A, seh1, Nup44A, Nup44A/Seh1, Nucleoporin-44A, nucleoporin-44A, Seh1, CG8722, Nucleoporin 44A, FBgn 33247" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR020472=G-protein beta WD-40 repeat" CG8722 16-Dec-15 2015_12 ENSDARG00000004280(seh1l) YGL100W(SEH1) WBGene00003804(npp-18) ENSXETG00000019668(seh1l) ENSMUSG00000079614(Seh1l) ENSG00000085415(SEH1L) "viable,recessive,female semi-sterile,visible,partially lethal - majority die,some die during pupal stage" "egg chamber,germarium,oocyte,centriole,microtubule,eye,trichogen cell,mesothoracic tergum" DRSC07248 I -0.27118393 1.546647239 0.146521244 0.36702857 -0.022626356 -0.35121396 FBgn0061200 Nup153 Nucleoporin 153kD http://flybase.net/reports/FBgn0061200.html FBgn0030762 protein_coding_gene "0005487=nucleocytoplasmic transporter activity, 0031490=chromatin DNA binding, 0017056=structural constituent of nuclear pore, 0008270=zinc ion binding" "0051298=centrosome duplication, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006607=NLS-bearing protein import into nucleus, 0007184=SMAD protein import into nucleus, 0006325=chromatin organization, 0006999=nuclear pore organization, 0006338=chromatin remodeling, 0022008=neurogenesis, 0006606=protein import into nucleus" "0005813=centrosome, 0072686=mitotic spindle, 0034399=nuclear periphery, 0005634=nucleus, 0005643=nuclear pore, 0044613=nuclear pore central transport channel, 0005635=nuclear envelope, 0005719=nuclear euchromatin" "NUP153, nup153, dNup153, CG4453, Nup153, dmNup153, Nucleoporin 153, Nup 153" "IPR001876=Zinc finger, RanBP2-type" CG4453 16-Dec-15 2015_12 ENSDARG00000020323(LOC571621) WBGene00003793(npp-7) ENSMUSG00000021374(Nup153) ENSG00000124789(NUP153) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,male germline cell,cyst progenitor cell,germline stem cell" DRSC19904 IE -1.964488456 -2.705440451 6.118500721 -5.615081464 0.116589008 -0.007277346 FBgn0267592 CCY Coiled-Coils Y http://flybase.net/reports/FBgn0267592.html "FBgn0045229, FBgn0046337, FBgn0085546, FBan0040968, FBgn0261335, FBgn0085541, FBan0040948" protein_coding_gene "NEST:bs20e03, CCY, CG45930, bs20e03.y1, CG42620, Ccy, CG40948, CG40968, ccy" CG45930 16-Dec-15 2015_12 FBgn0262510 CR43080 http://flybase.net/reports/FBgn0262510.html pseudogene_attribute "CG43080, CG4164" CR43080 16-Dec-15 2015_12 FBgn0261848 CG42780 http://flybase.net/reports/FBgn0261848.html protein_coding_gene "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG42780 16-Dec-15 2015_12 FBgn0265761 CR44568 http://flybase.net/reports/FBgn0265761.html non_protein_coding_gene lincRNA.982 CR44568 16-Dec-15 2015_12 FBgn0030065 CG12075 http://flybase.net/reports/FBgn0030065.html protein_coding_gene IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) CG12075 16-Dec-15 2015_12 "viable,fertile" FBgn0014243 l(2)32Ad lethal (2) 32Ad http://flybase.net/reports/FBgn0014243.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0013539 l(2)ry50 lethal (2) ry50 http://flybase.net/reports/FBgn0013539.html gene "unnamed, l(2)50" 16-Dec-15 2015_12 lethal FBgn0265828 CR44617 http://flybase.net/reports/FBgn0265828.html non_protein_coding_gene CR44617 16-Dec-15 2015_12 FBgn0086305 scnt scanty http://flybase.net/reports/FBgn0086305.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0039523 CG12885 http://flybase.net/reports/FBgn0039523.html protein_coding_gene CG12885 16-Dec-15 2015_12 "viable,fertile" FBgn0036419 CG13482 http://flybase.net/reports/FBgn0036419.html protein_coding_gene CG13482 16-Dec-15 2015_12 viable FBgn0010359 ë_Try ë_Trypsin http://flybase.net/reports/FBgn0010359.html "FBgn0050028, FBgn0061399" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "gammaTrypsin, DmGammaTry, endo-I, SPH180, gamma-Try, Try, gummaTrypsin, BcDNA:RE40325, CG30028, endoproteinase I, gamma" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG30028 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" " larval stage | third instar , adult stage " larval digestive system | restricted

FBgn0053139 Ranbp11 Ranbp11 http://flybase.net/reports/FBgn0053139.html FBgn0034036 protein_coding_gene 0008536=Ran GTPase binding 0006886=intracellular protein transport "impbeta11, CG8212, imp-beta11, importin-beta11, SP49, ran-binding protein 11, CG33139" "IPR001494=Importin-beta, N-terminal domain, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG33139 16-Dec-15 2015_12 ENSDARG00000054224(zgc:91897) YPL125W(KAP120) ENSXETG00000014823(ipo11) ENSMUSG00000042590(Ipo11) ENSG00000086200(IPO11) "some die during pharate adult stage,neurophysiology defective,lethal - all die before end of P-stage,phototaxis defective,somatic clone,viable,body color defective" "bouton,neuromuscular junctionëÓM22-103),mesothoracic tergum" FBgn0266326 CR44991 http://flybase.net/reports/FBgn0266326.html non_protein_coding_gene CR44991 16-Dec-15 2015_12 FBgn0031191 Cp110 http://flybase.net/reports/FBgn0031191.html FBgn0052501 protein_coding_gene 0007099=centriole replication 0005814=centriole "DCP110, CG32501, CG14617, CP110" "IPR000048=IQ motif, EF-hand binding site" CG14617 16-Dec-15 2015_12 ENSMUSG00000033904(6330503K22Rik) ENSG00000103540(CCP110) "viable,lethal - all die before end of pupal stage,fertile" "axoneme,spermatocyte,centriole,wing disc" FBgn0002134 l(2)K215 lethal (2) K215 http://flybase.net/reports/FBgn0002134.html gene 16-Dec-15 2015_12 lethal FBgn0051700 CR31700 http://flybase.net/reports/FBgn0051700.html FBan0031700 pseudogene_attribute CG31700 CR31700 16-Dec-15 2015_12 FBgn0020907 Scp2 Sarcoplasmic calcium-binding protein 2 http://flybase.net/reports/FBgn0020907.html FBgn0025677 protein_coding_gene "0005509=calcium ion binding, 0003924=GTPase activity" 0016529=sarcoplasmic reticulum "SCP2, CE, Drosophila Ca[2+]-binding protein A.2, Dcabp-A.2, Ca2+-sensing low molecular weight GTPase, Cex, CG14904, Calexcitin, cex, Cex Ca2+-sensing low molecular weight, dSCP2, JHDK" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG14904 16-Dec-15 2015_12 WBGene00023408(cex-2) adult stage neuron &&of adult brain | restricted

viable FBgn0016705 Reg-10 Rhythmically expressed gene 10 http://flybase.net/reports/FBgn0016705.html gene "Drosophila Rhythmically expressed gene 10, Dreg-10" 16-Dec-15 2015_12 adult stage adult head

FBgn0019790 l(1)13 lethal (1) 13 http://flybase.net/reports/FBgn0019790.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0060711 l(3)S070204 lethal (3) S070204 http://flybase.net/reports/FBgn0060711.html gene 0702/04 16-Dec-15 2015_12 "lethal,recessive" FBgn0000399 cvl-5 crossveinless-like 5 http://flybase.net/reports/FBgn0000399.html gene cvl 16-Dec-15 2015_12 "visible,recessive" crossvein FBgn0003550 Suc Sucrase http://flybase.net/reports/FBgn0003550.html gene "SUCR, Sucr" 16-Dec-15 2015_12 FBgn0004647 N Notch http://flybase.net/reports/FBgn0004647.html "FBgn0000311, FBgn0002916, FBgn0017616, FBgn0024967, FBgn0026804" protein_coding_gene "0004872=receptor activity, 0005515=protein binding, 0004888=transmembrane receptor activity, 0005509=calcium ion binding" "0007293=germarium-derived egg chamber formation,0007460=R8 cell fate commitment,0007219=Notch signaling pathway,0007478=leg disc morphogenesis,0016360=sensory organ precursor cell fate determination,0042689=regulation of crystal cell differentiation,0016333=morphogenesis of follicular epithelium,0046329=-ve regulation of JNK cascade,0040008=regulation of growth,0046843=dorsal appendage formation,0050768=-ve regulation of neurogenesis,0035286=leg segmentation,0007450=dorsal/ventral pattern formation,imaginal disc,0007314=oocyte anterior/posterior axis specification,0007398=ectoderm development,0042686=regulation of cardioblast cell fate specification,0007015=actin filament organization,0048666=neuron development,0007346=regulation of mitotic cell cycle,0050767=regulation of neurogenesis,0007424=open tracheal system development,0007473=wing disc proximal/distal pattern formation,0007476=imaginal disc-derived wing morphogenesis,0035171=lamellocyte differentiation,0030720=oocyte localization involved in germarium-derived egg chamber formation,0035172=hemocyte proliferation,0007411=axon guidance,0009952=anterior/posterior pattern formation,0001708=cell fate specification,0046331=lateral inhibition,0035153=epithelial cell type specification,open tracheal system,0007451=dorsal/ventral lineage restriction,imaginal disc,0046667=compound eye retinal cell programmed cell death,0016330=second mitotic wave involved in compound eye morphogenesis,0035111=leg joint morphogenesis,0045944=+ve regulation of transcription from RNA pol II promoter,0007519=skeletal muscle tissue development,0045463=R8 cell development,0007422=peripheral nervous system development,0001745=compound eye morphogenesis,0035214=eye-antennal disc development,0008284=+ve regulation of cell proliferation,0007391=dorsal closure,0007419=ventral cord development,0010001=glial cell differentiation,0000122=-ve regulation of transcription from RNA pol II promoter,0008356=asymmetric cell division,0045316=-ve regulation of compound eye photoreceptor development,0045747=+ve regulation of Notch signaling pathway,0035155=-ve regulation of terminal cell fate specification,open tracheal system,0007447=imaginal disc pattern formation,0035157=-ve regulation of fusion cell fate specification,0030707=ovarian follicle cell development,0008347=glial cell migration,0035162=embryonic hemopoiesis,0035165=embryonic crystal cell differentiation,0045750=+ve regulation of S phase of mitotic cell cycle,0048749=compound eye development,0035170=lymph gland crystal cell differentiation,0045465=R8 cell differentiation,0008407=bristle morphogenesis,0007464=R3/R4 cell fate commitment,0042676=compound eye cone cell fate commitment,0048863=stem cell differentiation,0045595=regulation of cell differentiation,0007521=muscle cell fate determination,0030708=germarium-derived female germ-line cyst encapsulation,0007423=sensory organ development,0007297=ovarian follicle cell migration,0045468=regulation of R8 cell spacing in compound eye,0008045=motor axon guidance,0048190=wing disc dorsal/ventral pattern formation,0007616=long-term memory,0045466=R7 cell differentiation,0048477=oogenesis,0008587=imaginal disc-derived wing margin morphogenesis,0007155=cell adhesion,0007440=foregut morphogenesis,0007615=anesthesia-resistant memory,0007446=imaginal disc growth,0007403=glial cell fate determination,0030713=ovarian follicle cell stalk formation,0007474=imaginal disc-derived wing vein specification,0048542=lymph gland development,0001737=establishment of imaginal disc-derived wing hair orientation,0045165=cell fate commitment,0007498=mesoderm development,0030718=germ-line stem cell maintenance,0042688=crystal cell differentiation,0046666=retinal cell programmed cell death,0035167=larval lymph gland hemopoiesis,0048052=R1/R6 cell differentiation,0007298=border follicle cell migration,0042067=establishment of ommatidial planar polarity,0007157=heterophilic cell-cell adhesion,0009608=response to symbiont" "0043234=protein complex, 0005622=intracellular, 0005634=nucleus, 0005886=plasma membrane, 0005887=integral to plasma membrane, 0016021=integral to membrane, 0031410=cytoplasmic vesicle, 0035003=subapical complex, 0005912=adherens junction" "co, nd, Notc, shd, Ax, Abruptex, facet, 16-55, 1.1, fa, EG:163A10.2, EG:140G11.1, Chopped, anon-EST:Liang-1.12, Co, l(1)Ax, split, CT13012, Notch, n[fah], notchoid, notch, spl, dNotch, strawberry, l(1)3Cb, l(1)N, clone 1.12, Confluens, swb, CG3936, Chp, 16-178" "IPR000800=Notch domain, IPR008297=Notch, IPR011656=Notch, NODP domain, IPR020683=Ankyrin repeat-containing domain, IPR006209=EGF, IPR002110=Ankyrin repeat, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR006210=Epidermal growth factor-like, IPR013032=EGF-like region, conserved site, IPR013111=EGF, extracellular, IPR001881=EGF-like calcium-binding, IPR010660=Notch, NOD domain, IPR000742=Epidermal growth factor-like, type 3, IPR013091=EGF calcium-binding, IPR018097=EGF-like calcium-binding, conserved site" CG3936 16-Dec-15 2015_12 "ENSDARG00000052139(notch3),ENSDARG00000043130(notch2)" WBGene00003482(mua-3) "ENSXETG00000000757(NOTCH1),ENSXETG00000017225(),ENSXETG00000002570(NOTCH3)" "ENSMUSG00000027878(Notch2),ENSMUSG00000026923(Notch1)" "ENSG00000148400(NOTCH1),ENSG00000134250(NOTCH2)" " embryonic stage | stage 17 , embryonic stage | stage 15 , embryonic stage , pupal stage , embryonic stage | stage 14 , embryonic stage | stage 1-16 , embryonic stage -- adult stage , adult stage , embryonic stage | stage 13 , embryonic stage | stage 10 , larval stage " " foregut

, ventral nerve cord

, ventral nerve cord primordium

, embryonic epidermis

, visual primordium

, procephalic neurogenic region

, embryonic central nervous system | resricted

" " adult stage && oogenesis stage , pupal stage , larval stage | third instar " " germarium region 3

, oocyte

, leg & joint | distal

, germarium region 2

, nurse cell

, germarium region 1

, ventral thoracic disc

, follicle cell

" "visible,dominant,neuroanatomy defective,hyperplasia,heat sensitive,lethal,recessive,neurogenic phenotype,somatic clone,decreased cell number,wild-type,viable,semi-lethal,cold sensitive,reduced,partially,fertile,planar polarity defective,memory defective,increased cell death,size defective,female sterile,immune response defective,decreased cell death,cell shape defective,courtship behavior defective,temperature conditional,mitotic cell cycle defective,poor,germline clone,maternal effect,male,female,female limited,sterile,female fertile,homeotic,chemosensitive behavior defective,increased cell number,cell non-autonomous" "wing blade-vein-margin,embryo/larva nervous system-brain,lamina anlage,medulla anlage,larval outer optic anlage,abdominal ventral multidendritic neuron,leg,prothoracic tibial- mesothoracic apical bristle,external sensory organ,vMP2&RP2&dMP2& pioneer neuron,neuroblast,embryo/larva CNS&PNS,wing disc,ectoderm,ventral nerve cord,epidermis,embryo/larva foregut-hindgut-tracheal system-salivary gland,adult thoracic sensillum,Malpighian tubule & primordium,tracheal branch primordium,follicle cell,centripetally migrating-polar-interfollicle cell,mitotic cell cycle,ventral thoracic disc,embryo/larva somatic muscle,joint,leg sensillum,tibia,femur,egg chamber,embryo epidermis & myoblast,macrochaeta,sensory mother cell,pCC&aCC&RP2sib&U&eo&multidendritic neuron,dorsal-ventral double row,segment border muscle,wing sensillum,embryo/larva dorsal vessel,support cell of the dorsal bipolar dendritic cell,scolopidial ligament cell,proventriculus inner/intermediate/outer layer primordium,embryo proventriculus,keyhole structure,midline glial cell,procrystal cell,embryo/1st instar larva cuticle,germline cyst,oocyte,anterior-posterior scutellar bristle,adult/embryo/larva midgut,germarium cap cell,ventral nerve cord primordium,chaeta,fascicle,eye,ommatidium,optic lobe,cortex of lamina,medulla/lamina neuropil,primary/secondary/tertiary pigment cell,lens, CNS,embryo/larva pericardial cell & stomatogastric nervous system,microchaeta,medulla,ocellar bristle,photoreceptor cell,ganglion mother cell,mushroom body,tormogen cell,medial triple row,dorsal triple row,sensillum campaniformium of anterior crossvein,antennal sense organ,trichome of the posterior wing margin,basal stalk,female germline stem cell,S2 cell-line, extended germ band embryo,abdominal dorsal acute muscle,pericardial cell,dorsal-mesothoracic-metathoracic acute muscle 1,dorsocentral-mesothoracic tarsal bristle,mesothoracic leg sensillum,mesothoracic metatarsus,supraalar-presutural-scutellar-sternopleural-orbital bristle,vibrissae,photoreceptor,head,twin sensillum of margin,wing nerve,antenna,mechanosensory sensory organ,subperineurial glial cell,ovary,pigment cell,border follicle cell,embryo/larva dorsal branch,nurse follicle cell,lymph gland primordium,cardioblast,embryo/larva lymph gland-lateral trunk-dorsal trunk,glial cell,chorion,dorsal appendage,nurse cell,oocyte associated follicle cell,trichogen cell,thecogen cell,longitudinal connective,eye-antennal disc,sensillum trichodeum-basiconicum-coeloconicum of antennal segment,sacculus,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,ovariole,dorsal pouch,adult head,oocyte nucleus,egg,intersegmental nerve,ventral midline,neuromere,dorsal multidendritic neuron ddaD&ddaE,crystal cell,metatarsus,hub cell,vMP2 tract,filopodium,ocellus,posterior notopleural-anterior-posterior supraalar bristle,posterior postalar-metathoracic bristle,costal vein,glioblast,posterior wing margin,embryo/larva corpus cardiacum,corpus cardiacum primordium,thorax,cuticle,salivary gland,postvertical bristle,muscle founder cell,sense organ,submarginal cell,antennal disc,morphogenetic furrow,adult thorax,NMJ bouton,embryo/larva NMJ,dorsal-ventral compartment boundary of the wing,Usib &EL & sensory neuron,embryo heart cardioblast,embryo/larva trachea,myoblast,embryo large intestine,C1 chordotonal organ precursor cell,oenocyte primordium,mesothoracic-metathoracic-prothoracic dorsal oblique muscle,transverse & acute muscle,visceral& somatic mesoderm,subesophageal ganglion neuron,tarsal segment,external sensory organ precursor cell,ommatidial precursor cluster,lobula,bract,follicle stem cell,embryo/larva muscle system,abdominal-mesothoracic-metathoracic-prothoracic intersegmental nerve,adult midgut precursor cell|late,myoblast,segmental nerve,adult muscle precursor cell,anterior crossvein,socket,male genitalia,cone cell,retina|adult stage,enterocyte of posterior adult midgut epithelium,intestinal stem cell,enteroendocrine cell" FBgn0000157 Dll Distal-less http://flybase.net/reports/FBgn0000157.html "FBgn0010474, FBgn0026807, FBgn0063133" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007485=imaginal disc-derived male genitalia development, 0035215=genital disc development, 0035114=imaginal disc-derived appendage morphogenesis, 0048264=determination of ventral identity, 0048728=proboscis development, 0010629=negative regulation of gene expression, 0007480=imaginal disc-derived leg morphogenesis, 0007469=antennal development, 0007487=analia development, 0008587=imaginal disc-derived wing margin morphogenesis, 0007479=leg disc proximal/distal pattern formation, 0007449=proximal/distal pattern formation, imaginal disc, 0045893=positive regulation of transcription, DNA-templated, 0042048=olfactory behavior, 0016319=mushroom body development, 0010092=specification of organ identity, 0021553=olfactory nerve development" 0005634=nucleus "l(2)387, Brista, dll, DLL, dl, Ba, CG3629, l(2)01092, E(Arp), En(Arp), 2.7, distalless, BcDNA:LP01770, distal-less, Art, Enhancer of Arp, Distall-less, Distalless" "IPR000047=Helix-turn-helix motif, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG3629 16-Dec-15 2015_12 "ENSDARG00000011956(dlx4a),ENSDARG00000071560(dlx4b)" "ENSMUSG00000023391(Dlx2),ENSMUSG00000029755(Dlx5),ENSMUSG00000001510(Dlx3)" "ENSG00000115844(DLX2),ENSG00000105880(DLX5),ENSG00000064195(DLX3)" " larval stage | second instar , larval stage | first instar , embryonic stage , larval stage | third instar " embryonic stage | extended germ band " maxillary segment

, dorsal prothoracic disc primordium

, labral segment

, labial disc primordium

, dorsal metathoracic disc primordium

" "visible,dominant,lethal,homeotic,recessive,chemosensitive behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,neuroanatomy defective,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,cold sensitive,lethal - all die before end of larval stage,some die during larval stage" "antenna,tarsal segment,distal,third segment of antenna,leg,ectopic,mushroom body pedunculus | embryonic stage 12,Kenyon cell | embryonic stage 12,mushroom body vertical lobe | embryonic stage 12,mushroom body medial lobe | embryonic stage 12,unguis,prothoracic metatarsus,sex comb,hypostomal sclerite,embryonic/larval labial organ,antennal sense organ,terminal organ,Keilin's organ,femur,tibia,arista,metatarsus,proximal,dorsal organ,mushroom body pedunculus,Kenyon cell,mushroom body vertical lobe,mushroom body medial lobe,somatic clone,wing margin bristle,cell autonomous,adult cuticle,anal plate,ventral thoracic disc,trochanter,macrochaeta & leg | somatic clone,mesothoracic femoral bract,mesothoracic tibial bract,metathoracic femoral bract,metathoracic tibial bract,prothoracic femoral bract,prothoracic tibial bract,second segment of antenna,dorsal triple row,medial triple row,ventral triple row,dorsal double row,ventral double row,wing vein,cell non-autonomous,wing,posterior compartment,anterior compartment,wing & macrochaeta | somatic clone,male,epiproct,female,distiproboscis,tibia & macrochaeta,macrochaeta,antennal segment 2 & macrochaeta,femur & macrochaeta,adult hindgut,female gonopod,cold sensitive,peripheral nervous system,adult head,female genitalia,male genitalia,analia,precursor,eye,haltere,head,wing margin,joint,bract" DRSC04610 I -1.913149107 0.038014634 -0.577701054 0.271201117 0.538541364 -1.361151523 FBgn0037678 CG16749 http://flybase.net/reports/FBgn0037678.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP91 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG16749 16-Dec-15 2015_12 "ENSMUSG00000030713(Klk7),ENSMUSG00000064023(Klk8),ENSMUSG00000054046(Klk13),ENSMUSG00000067616(Klk11),ENSMUSG00000074155(Klk5),ENSMUSG00000044737(Klk14),ENSMUSG00000044485(Klk1b11),ENSMUSG00000059042(Klk1b9),ENSMUSG00000044430(Klk12),ENSMUSG00000055193(Klk15),ENSMUSG00000050063(Klk6),ENSMUSG00000066515(Klk1b3),ENSMUSG00000063177(Klk1b27),ENSMUSG00000063133(Klk1b1),ENSMUSG00000063903(Klk1),ENSMUSG00000063713(Klk1b24),ENSMUSG00000066516(Klk1b21),ENSMUSG00000030693(Klk10),ENSMUSG00000053719(Klk1b26),ENSMUSG00000060177(Klk1b22),ENSMUSG00000066513(Klk1b4),ENSMUSG00000066512(Klk1b5),ENSMUSG00000063089(Klk1b8),ENSMUSG00000006948(Klk4),ENSMUSG00000047884(Klk9),ENSMUSG00000038968(Klk1b16)" "ENSG00000167759(KLK13),ENSG00000167757(KLK11),ENSG00000129455(KLK8),ENSG00000167755(KLK6),ENSG00000129437(KLK14),ENSG00000167754(KLK5),ENSG00000167751(KLK2),ENSG00000142515(KLK3),ENSG00000174562(KLK15),ENSG00000213022(KLK9),ENSG00000169035(KLK7),ENSG00000167748(KLK1),ENSG00000186474(KLK12),ENSG00000167749(KLK4),ENSG00000129451(KLK10)" viable FBgn0267445 Su(Ste):CR45795 Supressor of Stellate:CR45795 http://flybase.net/reports/FBgn0267445.html non_protein_coding_gene CR45795 CR45795 16-Dec-15 2015_12 FBgn0039832 CG15563 http://flybase.net/reports/FBgn0039832.html protein_coding_gene CG15563 16-Dec-15 2015_12 viable DRSC15101 EK 0.311745021 -0.64290603 -2.435719221 0.158246264 2.426189718 0.454117504 FBgn0067099 H66 H66 http://flybase.net/reports/FBgn0067099.html gene 16-Dec-15 2015_12 "visible,lethal" "chaeta,trichogen cell" FBgn0052185 edin elevated during infection http://flybase.net/reports/FBgn0052185.html protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0006959=humoral immune response, 0050830=defense response to Gram-positive bacterium" "0005576=extracellular region, 0005615=extracellular space" "Edin, CG32185" CG32185 16-Dec-15 2015_12 "partially lethal - majority die,short lived,immune response defective,conditional,viable,visible" trichogen cell DRSC09488 E 0.922479154 0.499418105 1.652986544 0.985368951 -1.086590042 0.494352404 FBgn0039114 Lsd-1 Lipid storage droplet-1 http://flybase.net/reports/FBgn0039114.html protein_coding_gene "0019915=lipid storage, 0006642=triglyceride mobilization, 0010883=regulation of lipid storage, 0022008=neurogenesis, 0034389=lipid particle organization, 0010898=positive regulation of triglyceride catabolic process, 1990044=protein localization to lipid particle" "0005811=lipid particle, 0032994=protein-lipid complex" "Lsdp1, LSDP1, DmPLIN1, perilipin, lsd1, Lipid storage droplets surface binding protein, plin1, LSD-1, Lsd1, PLIN1, CG10374, lipid storage droplet protein 1" IPR004279=Perilipin CG10374 16-Dec-15 2015_12 "ENSDARG00000042332(plin2),ENSDARG00000013711,ENSDARG00000054048(LOC100001938)" "ENSMUSG00000011305(Plin5),ENSMUSG00000024197(Plin3),ENSMUSG00000028494(Plin2),ENSMUSG00000030546(Plin1)" "ENSG00000105355(PLIN3),ENSG00000147872(PLIN2),ENSG00000214456(PLIN5)" "starvation stress response defective,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable,stress response defective,large body" "embryonic/larval fat body,lipid particle,ganglion mother cell,mesothoracic tergum,lipid particlefat" FBgn0019681 mor(1)10 mortality gene (1)10 http://flybase.net/reports/FBgn0019681.html gene 16-Dec-15 2015_12 short lived FBgn0038510 CG14331 http://flybase.net/reports/FBgn0038510.html protein_coding_gene CG14331 16-Dec-15 2015_12 viable FBgn0035238 CG12104 http://flybase.net/reports/FBgn0035238.html protein_coding_gene IPR009071=High mobility group box domain CG12104 16-Dec-15 2015_12 "ENSDARG00000032317(tox),ENSDARG00000035773,ENSDARG00000063420(zgc:175137)" viable FBgn0058081 CG40081 http://flybase.net/reports/FBgn0058081.html protein_coding_gene 16-Dec-15 2015_12 FBgn0025820 JTBR JTBR http://flybase.net/reports/FBgn0025820.html "FBgn0025210, FBgn0035275, FBgn0063663" protein_coding_gene 0016021=integral component of membrane "BcDNA:RH07980, dJTBR, CG1935, Jumping Translocation Breakpoint, unnamed, dJTB-like, anon-fast-evolving-2G4, anon-EST:fe2G4" IPR008657=Jumping translocation breakpoint CG1935 16-Dec-15 2015_12 WBGene00002180(jtr-1) ENSMUSG00000027937(Jtb) ENSG00000143543(JTB) FBgn0067633 70 70 http://flybase.net/reports/FBgn0067633.html gene 16-Dec-15 2015_12 "viable,fertile,courtship behavior defective,female" FBgn0067743 l(1)G0284 lethal (1) G0284 http://flybase.net/reports/FBgn0067743.html FBgn0045042 gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0045980 niki nimA-like kinase http://flybase.net/reports/FBgn0045980.html FBgn0039230 protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity" "0006468=protein phosphorylation, 0048812=neuron projection morphogenesis" 0005929=cilium "Niki, CG10951, NEK1" "IPR000408=Regulator of chromosome condensation, RCC1, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG10951 16-Dec-15 2015_12 ENSDARG00000045626(nek8) WBGene00021461(nekl-1) "ENSXETG00000019232(nek8),ENSXETG00000013239(NEK9)" "ENSMUSG00000017405(Nek8),ENSMUSG00000034290(Nek9)" "ENSG00000160602(NEK8),ENSG00000119638(NEK9)" "lethal,viable" FBgn0016664 Hrp44 Hrp44 http://flybase.net/reports/FBgn0016664.html gene 0003697=single-stranded DNA binding "0005634=nucleus, 0005730=nucleolus" hrp44 16-Dec-15 2015_12 FBgn0034639 CG15673 http://flybase.net/reports/FBgn0034639.html protein_coding_gene CG15673 16-Dec-15 2015_12 viable FBgn0037896 ninaG ninaG http://flybase.net/reports/FBgn0037896.html protein_coding_gene "0016491=oxidoreductase activity, 0050660=flavin adenine dinucleotide binding, 0016614=oxidoreductase activity, acting on CH-OH group of donors" "0001523=retinoid metabolic process, 0055114=oxidation-reduction process, 0046154=rhodopsin metabolic process, 0006810=transport, 0007601=visual perception" "NinaG, CG6728" "IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal" CG6728 16-Dec-15 2015_12 "viable,fertile,neurophysiology defective" "rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rough endoplasmic reticulum & eye photoreceptor cell,eye" FBgn0060360 l(3)S140009b lethal (3) S140009b http://flybase.net/reports/FBgn0060360.html gene 1400/09 16-Dec-15 2015_12 "lethal,recessive" FBgn0263632 mir-3642 mir-3642 stem loop http://flybase.net/reports/FBgn0263632.html "FBgn0262132, FBgn0263549" miRNA_gene CR43534 CR43534 16-Dec-15 2015_12 viable FBgn0264840 CR44048 http://flybase.net/reports/FBgn0264840.html non_protein_coding_gene CR44048 16-Dec-15 2015_12 FBgn0003160 pts ponte thermosensible http://flybase.net/reports/FBgn0003160.html gene 16-Dec-15 2015_12 "female sterile,recessive,heat sensitive" FBgn0036804 Sgf11 SAGA associated factor 11kDa http://flybase.net/reports/FBgn0036804.html protein_coding_gene 0005515=protein binding "0006325=chromatin organization, 0016578=histone deubiquitination, 0007412=axon target recognition, 0008347=glial cell migration, 0051726=regulation of cell cycle, 0006355=regulation of transcription, DNA-templated" "0071819=DUBm complex, 0000124=SAGA complex, 0005634=nucleus" "Sgf11, dSgf11, CG13379" "IPR013246=SAGA complex, Sgf11 subunit" CG13379 16-Dec-15 2015_12 "lethal,recessive,neuroanatomy defective,enhancer of variegation,dominant,viable,fertile,body color defective" "axon & photoreceptor cell R2,axon & photoreceptor cell R3,axon & photoreceptor cell R4,axon & photoreceptor cell R5,ventral interface glial cell,dorsal interface glial cell,mesothoracic tergum" FBgn0264867 CR44058 http://flybase.net/reports/FBgn0264867.html non_protein_coding_gene lincRNA.33 CR44058 16-Dec-15 2015_12 FBgn0011766 E2f1 E2F transcription factor 1 http://flybase.net/reports/FBgn0011766.html "FBgn0010918, FBgn0011343, FBgn0011351, FBgn0011520, FBgn0011767, FBgn0013944, FBgn0016652" protein_coding_gene "0005515=protein binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0008134=transcription factor binding, 0001012=RNA polymerase II regulatory region DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007476=imaginal disc-derived wing morphogenesis, 0019730=antimicrobial humoral response, 0010628=positive regulation of gene expression, 0000082=G1/S transition of mitotic cell cycle, 0035167=larval lymph gland hemopoiesis, 0007444=imaginal disc development, 0040007=growth, 0000083=regulation of transcription involved in G1/S transition of mitotic cell cycle, 0048666=neuron development, 1900117=regulation of execution phase of apoptosis, 0048813=dendrite morphogenesis, 0060537=muscle tissue development, 0007307=eggshell chorion gene amplification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0008284=positive regulation of cell proliferation, 0051726=regulation of cell cycle, 0045893=positive regulation of transcription, DNA-templated, 0042023=DNA endoreduplication, 0045850=positive regulation of nurse cell apoptotic process, 0035206=regulation of hemocyte proliferation, 0045476=nurse cell apoptotic process, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0035189=Rb-E2F complex, 0005634=nucleus" "E(var)93E, dE2F1, E(var)3-95E, E2F1, CG6376, l(3)rM729, E2F, l(3)j3C2, de2f1, E(var)3-93E, E2F transcription factor, dE2f, E2-promoter binding factor, l(3)j3B1, Evar(3)164, DRTF1/E2F, E2f, DmE2F-1, e2f1, Dp, e2f, l(3)07172, E(Sev-CycE)3A, E2F-1, dE2f1, dE2F, def21, E2f1, drosE2F1" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR015633=E2F Family, IPR003316=E2F/DP family, winged-helix DNA-binding domain" CG6376 16-Dec-15 2015_12 "ENSDARG00000029358(e2f4),ENSDARG00000038812" "ENSXETG00000000021(E2F3),ENSXETG00000021428(E2F1)" "ENSMUSG00000016477(E2f3),ENSMUSG00000018983(E2f2),ENSMUSG00000027490(E2f1)" "ENSG00000112242(E2F3),ENSG00000007968(E2F2),ENSG00000101412(E2F1)" " embryonic stage , embryonic stage | stage 16 , embryonic stage | stage 7 , embryonic stage | stage >=12 , embryonic stage | stage 13 , embryonic stage | stage 8-11 , embryonic stage | stage 1 , embryonic stage | stage 1-4 , embryonic stage | stage 9-11 , embryonic stage | stage 12 , embryonic stage | stage >=10 , embryonic stage | early " " embryonic central nervous system

, embryonic/larval midgut

, ventral furrow

, embryonic brain

, anterior embryonic/larval midgut

, embryonic/larval foregut

, mesoderm

,

ubiquitous , neuroblast

, embryonic central nervous system | restricted

, posterior embryonic/larval midgut

" "female sterile,visible,increased cell death,heat sensitive,radiation resistant,cell non-autonomous,increased cell number,neuroanatomy defective,homeotic,partially lethal - majority die,lethal,cell death defective,viable,partially,recessive,mitotic cell cycle defective,fertile,decreased cell size,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,enhancer of variegation,melanotic mass phenotype,behavior defective,dominant,decreased cell death,maternal effect,female fertile,male fertile,non-suppressor of variegation,non-enhancer of variegation,some die during pupal stage,increased cell size,somatic clone,suppressor of variegation,wild-type" "eye,heterochromatin & nurse cell, with E2f191,ommatidium,1st posterior cell,wing,wing disc,cell non-autonomous,neuroblast NB6-4 of thorax,ectopic,neuroblast NB6-4 of abdomen,wing vein,wing blade,wing pouch,abdomen,macrochaeta,nurse cell,chorion,follicle cell,ovary,heterochromatin & nurse celle-BS2),nuclear chromosome & nurse celle-BS2),nuclear membrane & nurse celle-BS2),polar body nucleus,oocyte,egg,dorsal appendage,posterior | third instar larval stage,mitotic cell cycle,antenna,interommatidial bristle,heart primordium,anterior midgut primordium,posterior midgut primordium,eye disc posterior to the morphogenetic furrow,posterior compartment,imaginal disc,embryonic/larval optic lobe,eye disc,eye disc & mitotic cell cycle,epidermis,peripheral nervous system,chordotonal organ,heterochromatin & nurse cell, with E2f1hs.PD,neuroblast NB6-4,embryonic thorax & neuron,eye-antennal disc,eye photoreceptor cell,rhabdomere,midgut primordium & S phase,follicle stem cell,somatic clone,trichogen cell,mesothoracic tergum,larval outer optic anlage,photoreceptor cell,central nervous system,neuroblast,larval optic anlage" DRSC16655 IEK -3.069120889 -2.378068942 -2.579935112 -2.670236433 10.0646481 14.85815627 FBgn0030933 CG6470 http://flybase.net/reports/FBgn0030933.html FBgn0044744 protein_coding_gene 0046872=metal ion binding anon-WO0140519.137 "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG6470 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052783 CG32783 http://flybase.net/reports/FBgn0052783.html protein_coding_gene CG32783 16-Dec-15 2015_12 FBgn0013678 mt:Cyt-b mitochondrial Cytochrome b http://flybase.net/reports/FBgn0013678.html "FBgn0002867, FBgn0025273" protein_coding_gene "0009055=electron carrier activity, 0008121=ubiquinol-cytochrome-c reductase activity" "0007283=spermatogenesis, 0006122=mitochondrial electron transport, ubiquinol to cytochrome c" "0045275=respiratory chain complex III, 0005750=mitochondrial respiratory chain complex III" "Cyt-b, Cytochrome-b, cyt b, Cyt b, mitochondrial cytochrome b, CytB, unnamed, mt:cyt-b, cytb, cytochrome b, anon-fast-evolving-1B1, Cytob, Cyt B, CG34090, Cytochrome b, Cytb, CYTB, anon-EST:fe1B1" "IPR027387=Cytochrome b/b6-like domain, IPR005797=Cytochrome b/b6, N-terminal, IPR030689=Cytochrome b, IPR016174=Di-haem cytochrome, transmembrane, IPR005798=Cytochrome b/b6, C-terminal" CG34090 16-Dec-15 2015_12 ENSDARG00000063924 "Q0105(COB),Q0120(BI4)" WBGene00000829(ctb-1) ENSMUSG00000064370 ENSG00000198727 "short lived,maternal effect,male sterile" "testis,maternal effect,spermatid" FBgn0085754 CR40597 http://flybase.net/reports/FBgn0085754.html FBan0040597 rRNA_gene CR40597 16-Dec-15 2015_12 FBgn0031707 CG14020 http://flybase.net/reports/FBgn0031707.html protein_coding_gene "0007030=Golgi organization, 0045930=negative regulation of mitotic cell cycle" IPR019306=Transmembrane protein 231 CG14020 16-Dec-15 2015_12 ENSDARG00000042272(tmem231) ENSXETG00000003575(TMEM231) ENSMUSG00000031951(Tmem231) ENSG00000205084(TMEM231) "viable,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0264439 CR43857 http://flybase.net/reports/FBgn0264439.html non_protein_coding_gene CR43857 16-Dec-15 2015_12 FBgn0005047 E(var)55 Enhancer of variegation 55 http://flybase.net/reports/FBgn0005047.html gene 16-Dec-15 2015_12 FBgn0002577 m miniature http://flybase.net/reports/FBgn0002577.html FBgn0030333 protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0003383=apical constriction, 0000902=cell morphogenesis, 0016476=regulation of embryonic cell shape, 0007015=actin filament organization, 0007476=imaginal disc-derived wing morphogenesis, 0035017=cuticle pattern formation, 0007160=cell-matrix adhesion, 0009913=epidermal cell differentiation" "0016324=apical plasma membrane, 0016021=integral component of membrane" "Miniature, min, CG9369, Min, M" IPR001507=Zona pellucida domain CG9369 16-Dec-15 2015_12 WBGene00009961(cutl-7) "visible,viable,recessive,semidominant,fertile,female sterile,dominant,male fertile,male sterile,body color defective" "wing,denticle,macrochaeta" FBgn0022811 E(faf)E337 Enhancer of faf E337 http://flybase.net/reports/FBgn0022811.html gene 16-Dec-15 2015_12 "viable,visible" eye FBgn0001762 l(1)M19 lethal (1) M19 http://flybase.net/reports/FBgn0001762.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040169 l(1)G0362 lethal (1) G0362 http://flybase.net/reports/FBgn0040169.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003082 phr photorepair http://flybase.net/reports/FBgn0003082.html "FBgn0011299, FBgn0014003" protein_coding_gene 0003904=deoxyribodipyrimidine photo-lyase activity 0006281=DNA repair "CPD photolyase, DNA photolyase, photolyase, Dm CPD, anonOV1, anonymous ovarian cDNA 1, Phl, CG11205-PA, C2PHR, Photolyase, anon-OV1, CG11205" "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR006050=DNA photolyase, N-terminal, IPR005101=Cryptochrome/photolyase FAD-binding domain, IPR008148=DNA photolyase, class 2" CG11205 16-Dec-15 2015_12 ENSDARG00000054999(zgc:66475) "DNA repair defective,viable" FBgn0015768 Mst317 Male-specific transcript 317 http://flybase.net/reports/FBgn0015768.html gene 16-Dec-15 2015_12 FBgn0046301 CG7148 http://flybase.net/reports/FBgn0046301.html FBgn0037136 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex "FBXL12, BEST:GH10766" CG7148 16-Dec-15 2015_12 viable FBgn0051742 Prosë_5R2 Proteasome ë_5 subunit-related 2 http://flybase.net/reports/FBgn0051742.html FBgn0043961 protein_coding_gene "0004298=threonine-type endopeptidase activity, 0004175=endopeptidase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0019774=proteasome core complex, beta-subunit complex, 0000502=proteasome complex" "Prosbeta5R2, AE003657 - proteasome beta subunit, beta5R2, CG31742, anon-AE003657.1, 31742" "IPR016050=Proteasome beta-type subunit, conserved site, IPR000243=Peptidase T1A, proteasome beta-subunit, IPR001353=Proteasome, subunit alpha/beta, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR023333=Proteasome B-type subunit" CG31742 16-Dec-15 2015_12 YPR103W(PRE2) WBGene00003951(pbs-5) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263576 mir-4919 mir-4919 stem loop http://flybase.net/reports/FBgn0263576.html miRNA_gene "CR43561, dme-mir-4919, miR-4919" CR43561 16-Dec-15 2015_12 FBgn0038390 Rbf2 Retinoblastoma-family protein 2 http://flybase.net/reports/FBgn0038390.html protein_coding_gene "0008134=transcription factor binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0044212=transcription regulatory region DNA binding, 0003677=DNA binding" "2000134=negative regulation of G1/S transition of mitotic cell cycle, 0051726=regulation of cell cycle, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0031523=Myb complex, 0005634=nucleus, 0035189=Rb-E2F complex" "CG5083, RBF2, rbf2, RB" "IPR024599=Retinoblastoma-associated protein, N-terminal, IPR002720=Retinoblastoma-associated protein, A-box, IPR028309=Retinoblastoma protein family, IPR002719=Retinoblastoma-associated protein, B-box, IPR013763=Cyclin-like" CG5083 16-Dec-15 2015_12 WBGene00003020(lin-35) FBgn0051942 tRNA:CR31942 transfer RNA:CR31942 http://flybase.net/reports/FBgn0051942.html FBgn0060074 tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033447=AGA codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "chr2L.trna1-ArgTCT, AE002638.trna8-ArgTCT, tRNA:R:TCT:AE002638-a, CR31942" CR31942 16-Dec-15 2015_12 FBgn0037837 CG14693 http://flybase.net/reports/FBgn0037837.html protein_coding_gene "IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like, IPR014710=RmlC-like jelly roll fold" CG14693 16-Dec-15 2015_12 ENSMUSG00000038085 ENSG00000149646(C20orf152) "viable,fertile,auditory perception defective" DRSC14916 E -0.240566947 0.810442391 1.64201163 0.337215676 -0.715837331 -0.504737787 FBgn0016993 ms(3)1104C ms(3)1104C http://flybase.net/reports/FBgn0016993.html gene 16-Dec-15 2015_12 FBgn0266631 CR45138 http://flybase.net/reports/FBgn0266631.html non_protein_coding_gene CR45138 16-Dec-15 2015_12 FBgn0002525 Lam Lamin http://flybase.net/reports/FBgn0002525.html "FBgn0001930, FBgn0010582, FBgn0014344" protein_coding_gene "0005198=structural molecule activity, 0005515=protein binding" "0007417=central nervous system development, 0035262=gonad morphogenesis, 0090435=protein localization to nuclear envelope, 0007084=mitotic nuclear envelope reassembly, 0046331=lateral inhibition, 0006342=chromatin silencing, 0007097=nuclear migration, 0050777=negative regulation of immune response, 0048546=digestive tract morphogenesis, 0007569=cell aging, 0008285=negative regulation of cell proliferation, 0051297=centrosome organization, 0006998=nuclear envelope organization, 0008344=adult locomotory behavior, 0071763=nuclear membrane organization, 0031081=nuclear pore distribution, 0001745=compound eye morphogenesis, 0070870=heterochromatin maintenance involved in chromatin silencing, 0007430=terminal branching, open tracheal system, 0040003=chitin-based cuticle development, 0007283=spermatogenesis" "0005638=lamin filament, 0005811=lipid particle, 0005813=centrosome, 0072686=mitotic spindle, 0005634=nucleus, 0005635=nuclear envelope, 0005637=nuclear inner membrane, 0005875=microtubule associated complex, 0005652=nuclear lamina" "Lam(Dm0), B-type Lamin, alpha-Lamin, lamin Dm0, LaminDm, Dm(0), l(2)gdh-7, LAM, nlam, lamin Dm, DM[[O]], Lam Dm[[0]], nuclear lamin, Lamin D, Lam[[Dm0]], jf27, DmLamin, LamDm[[o]], LamDm, Dm[[0]], lamin A, Lamin Dm0, l(2)04643, lamin D[[m0]], Dm[[1]], lamin Dm[[0]], lamDm[[0]], intermediate filament-like lamina, Lamin D[[o]], LamDm[[0]], 2459, misguided, l(2)25Ec, lamin D[[m]]0, Dmo, l(2)jf27, Dm1, Lamin DmO, misg, D5, CG6944, l(2)gdh7, Lamin B, DmO, LaminDm0, n-lamin, lamin D[[0]], Dm[[2]], lethal(2)25Ec, Dm[[mit]], lam, lamin, Lamin Dmo, LamDm0, Lamin-B, Dm0, lamDm0, Lamin, Lamin Dm[[0]], misrouted, Dm[[o]], Dm, 74/76, D[[m0]], B-type lamin, lamin B, Dm2" "IPR027696=Lamin, IPR001322=Lamin Tail Domain, IPR001664=Intermediate filament protein" CG6944 16-Dec-15 2015_12 "ENSDARG00000009933(lmnb2),ENSDARG00000044299(lmnb1),ENSDARG00000013415(lmna)" WBGene00003052(lmn-1) "ENSXETG00000001795(lmnb2),ENSXETG00000005162(lmnb1),ENSXETG00000024161(LMNA),ENSXETG00000015792(lmna)" "ENSMUSG00000024590(Lmnb1),ENSMUSG00000062075(Lmnb2),ENSMUSG00000028063(Lmna)" "ENSG00000113368(LMNB1),ENSG00000176619(LMNB2),ENSG00000160789(LMNA)" " embryonic stage -- adult stage , embryonic stage " " embryonic stage , embryonic stage -- adult stage , embryonic stage | early , larval stage , oogenesis stage " "lethal,partially lethal - majority die,locomotor behavior defective,gravitaxis defective,viable,fertile,sterile,female sterile,recessive,male sterile,partially,flightless,uncoordinated,flight defective,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,some die during third instar larval stage,wild-type,female,germline clone,developmental rate defective,cell growth defective,partially lethal - majority live,visible,short lived,temperature conditional" "presumptive embryonic/larval muscle system,ovary,ovariole,oocyte,spermatozoon,nuclear pore,annulate lamellae,nuclear membrane,eye disc & nucleus | ectopic | somatic clone,presumptive embryonic/larval tracheal system,egg chamber,germline clone,egg,dorsal appendage,supernumerary,nurse cell,dorsal branch primordium,ganglionic branch primordium,nucleus & eye photoreceptor cell & eye disc,nuclear inner membrane,nuclear outer membrane,gamete,female,nuclear membrane | pharate adult stage,pigment cell,adult cuticle,cystocyte & nucleus & pharate adult,gonad | male & pharate adult,eye & nucleus & pharate adult,subesophageal ganglion,adult midgut,longitudinal muscle,eye,rhabdomerecl-h4),eye disc & nucleus | ectopiccl-h4),rhabdomere,eye disc & nucleus | ectopic,ommatidium,nucleus | adult stageMhc.Switch.PO,adult fat body,nucleus | adult stageSwitch1.106,brain,nucleus | adult stageelav.Switch.PO,chaeta,trichogen cell,cyst progenitor cell,germline stem cell,cyst cell,male germline cell" FBgn0027587 CG7028 http://flybase.net/reports/FBgn0027587.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0008360=regulation of cell shape, 0006468=protein phosphorylation, 0007155=cell adhesion, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" "0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome" "prp4, FBgn0027587, PRP4, BcDNA:GH04978" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG7028 16-Dec-15 2015_12 "ENSDARG00000040310(prpf4b),ENSDARG00000008784(zgc:56223)" WBGene00004186(prpf-4) ENSXETG00000011416(PRPF4B) ENSMUSG00000021413(Prpf4b) ENSG00000112739(PRPF4B) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0001257 ImpL2 Ecdysone-inducible gene L2 http://flybase.net/reports/FBgn0001257.html protein_coding_gene 0005520=insulin-like growth factor binding "0007155=cell adhesion, 0046627=negative regulation of insulin receptor signaling pathway, 0046628=positive regulation of insulin receptor signaling pathway, 0008340=determination of adult lifespan, 0010888=negative regulation of lipid storage" "0005615=extracellular space, 0005576=extracellular region" "IMP-L2, IMPL2, CG15009, CT34862, Imp-L2, ImpL-2, Imp-12, ecdysone-inducible gene L2, neural and ectodermal development factor, GH28, Imaginal morphogenesis protein-late 2, Imaginal morphogenesis protein-Late 2" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG15009 16-Dec-15 2015_12 "WBGene00006981(zig-4),WBGene00006980(zig-3),WBGene00006979(zig-2)" " embryonic stage | stage 8 , embryonic stage | stage 15-16 , embryonic stage | stage 9 , embryonic stage | stage 15-17 , embryonic stage | stage 15,16 , embryonic stage | cellular blastoderm " " neurogenic region

, embryonic/larval esophagus

, tracheal pit

, embryonic/larval pharynx

, bipolar dendrite neuron

, embryonic/larval posterior spiracle

, frontal head air sac

,

pair-rule " " embryonic stage | stage 16-17 , embryonic stage | stage 16,17 " " embryonic optic lobe primordium

, bipolar dendrite neuron

, procephalic segment

, multidendritic neuron

" "viable,fertile,hyperplasia,large body,stress response defective,lethal,small body,decreased cell size,somatic clone,developmental rate defective,long lived,female limited,RU486 conditional,short lived,wild-type" "ovary,eye" DRSC08666 K 0.091502141 -0.661047689 -0.522718027 -0.000434487 0.215414036 -1.501459974 FBgn0011570 cpb capping protein beta http://flybase.net/reports/FBgn0011570.html "FBgn0015012, FBgn0061517" protein_coding_gene "0046982=protein heterodimerization activity, 0003779=actin binding" "0035220=wing disc development, 0007018=microtubule-based movement, 0010591=regulation of lamellipodium assembly, 0030832=regulation of actin filament length, 0051016=barbed-end actin filament capping, 0007015=actin filament organization, 0030036=actin cytoskeleton organization, 0000902=cell morphogenesis, 0007298=border follicle cell migration, 0051490=negative regulation of filopodium assembly, 0007303=cytoplasmic transport, nurse cell to oocyte, 0046329=negative regulation of JNK cascade, 0045887=positive regulation of synaptic growth at neuromuscular junction" "0008290=F-actin capping protein complex, 0005737=cytoplasm, 0005912=adherens junction, 0005869=dynactin complex" "actin capping protein beta, bnd, J, capping protein Beta, CAPB_DROME, CapZ, CG17158, Capping proteins beta, capping protein beta, CP, Capping Protein, CP-beta, Ancpbeta, capping proteinbeta, Capping protein beta, Capping-protein-beta, burned, CP beta subunit, CPB, Cpb, capping protein, Capping protein, F-actin capping protein" "IPR001698=F-actin-capping protein subunit beta, IPR019771=F-actin capping protein, beta subunit, conserved site" CG17158 16-Dec-15 2015_12 ENSDARG00000046004 YIL034C(CAP2) WBGene00000293(cap-2) ENSXETG00000017607(CAPZB) ENSMUSG00000028745(Capzb) ENSG00000077549(CAPZB) embryonic stage -- adult stage " adult stage , embryonic stage -- adult stage " " muscle cell &&of thorax

, macrochaeta

" "wild-type,visible,recessive,somatic clone,lethal,cell migration defective,partially lethal - majority die,developmental rate defective,fertile,male,semi-sterile,dominant,female,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "eye,somatic clone,ommatidium,eye photoreceptor cell,interommatidial bristle,wing,adult abdomen,chaeta,eye photoreceptor cell & nucleus | somatic clone,border follicle cell,wing disc,rhabdomere,filopodium | supernumerary,trichogen cell & actin filament & pupa,sternopleural bristle,macrochaeta,egg,maternal effect,actin filament & egg chamber,nurse cell,macrochaeta & head,macrochaeta & thorax,actin cytoskeleton & eye disc | somatic clone,actin filament & dorsal mesothoracic disc & pupa | somatic clone,NMJ bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0060810 l(3)S054516 lethal (3) S054516 http://flybase.net/reports/FBgn0060810.html gene 0545/16 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038072 CG6225 http://flybase.net/reports/FBgn0038072.html protein_coding_gene 0004177=aminopeptidase activity 0022008=neurogenesis "IPR000994=Peptidase M24, structural domain, IPR028980=Creatinase/Aminopeptidase P, N-terminal, IPR000587=Creatinase, N-terminal, IPR029149=Creatinase/Aminopeptidase P/Spt16, N-terminal" CG6225 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible,body color defective" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0015268 Nap1 Nucleosome assembly protein 1 http://flybase.net/reports/FBgn0015268.html protein_coding_gene 0042393=histone binding "0035041=sperm chromatin decondensation, 0006338=chromatin remodeling, 0006334=nucleosome assembly, 0006355=regulation of transcription, DNA-templated" "0016590=ACF complex, 0005634=nucleus, 0005737=cytoplasm, 0005739=mitochondrion, 0005886=plasma membrane" "nucleosome assembly protein 1, dNap1, CG5330, Nap-1, dNap, NAP-1, dNAP-1, dNAP1, p56/dCAF-4, NAP1, nap1" IPR002164=Nucleosome assembly protein (NAP) CG5330 16-Dec-15 2015_12 "ENSDARG00000002400(nap1l1),ENSDARG00000068872,ENSDARG00000068868(nap1l4b),ENSDARG00000070560(nap1l4a)" YKR048C(NAP1) WBGene00017075(D2096.8) "ENSXETG00000013323(nap1l1),ENSXETG00000003664(NAP1L4)" "ENSMUSG00000058799(Nap1l1),ENSMUSG00000059119(Nap1l4)" "ENSG00000187109(NAP1L1),ENSG00000205531(NAP1L4)" " embryonic stage -- adult stage , embryonic stage | early " "viable,fertile,wild-type,suppressor of variegation,dominant,lethal,visible,partially lethal - majority die,some die during pupal stage" "investment cone,trichogen cell,mesothoracic tergum,eye" DRSC04626 K 0.252295169 0.308294835 -0.333035488 0.168113061 -1.530143096 1.261653866 FBgn0003867 tsl torso-like http://flybase.net/reports/FBgn0003867.html protein_coding_gene 0005122=torso binding "0008293=torso signaling pathway, 0009880=embryonic pattern specification, 0007362=terminal region determination, 0040018=positive regulation of multicellular organism growth, 0008595=anterior/posterior axis specification, embryo" 0005576=extracellular region "Torso-like, fs(3)00617, fs(3)torso-like, Dm-tsl, Tsl, torso like, torsolike, CG6705, Torsolike" IPR020864=Membrane attack complex component/perforin (MACPF) domain CG6705 16-Dec-15 2015_12 adult stage && oogenesis stage " follicle cell | posterior

, border follicle cell

, centripetally migrating follicle cell

" " embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | 0-9 hr " " embryonic/larval tracheal system

, organism | 80-100% egg length

, ventral nervous system

, organism | 0-20% egg length

, vitelline membrane

anterior & posterior " "developmental rate defective,female sterile,recessive,reduced,lethal,heat sensitive,wild-type,maternal effect,viable,visible,size defective,decreased cell size" "dorsal bridge,embryonic/first instar larval cuticle,denticle belt,abdominal segment 8,anal pad,abdominal 11 anal tuft,posterior spiracle primordium,filzkorper,head,embryonic/larval spiracle,ectopic,mouthpart,embryonic segment,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,telson,labrum,ocular segment,cephalic furrow,cephalopharyngeal skeleton,embryonic abdominal segment 8,embryo,anterior,posterior,embryonic head,embryonic telson,abdominal 8 ventral denticle belt,maternal effect,terminalia,embryonic thorax,embryonic abdomen,wing hair" FBgn0023023 CRMP Collapsin Response Mediator Protein http://flybase.net/reports/FBgn0023023.html "FBgn0027906, FBgn0062660" protein_coding_gene 0004157=dihydropyrimidinase activity "0007265=Ras protein signal transduction, 0051642=centrosome localization, 0006207='de novo' pyrimidine nucleobase biosynthetic process, 0045747=positive regulation of Notch signaling pathway, 0007613=memory" 0005737=cytoplasm "pyd2, dihydropyrimidine amidohydrolase, BcDNA:HL02693, Pyd2, EP3238, EP(3)3238, CG1411, dihydropyrimidinase, Collapsin Response Mediating Protein, unnamed, Collapsin response mediator protein, l(3)83Ba, DHP, crmp" "IPR011059=Metal-dependent hydrolase, composite domain, IPR011778=Hydantoinase/dihydropyrimidinase, IPR006680=Amidohydrolase-related" CG1411 16-Dec-15 2015_12 "ENSDARG00000038974,ENSDARG00000032083(dpysl2),ENSDARG00000056742(crmp1),ENSDARG00000057316(dpysl4),ENSDARG00000002587(dpysl3),ENSDARG00000011141(dpysl5a),ENSDARG00000059311" "WBGene00000964(dhp-2),WBGene00000963(dhp-1)" "ENSXETG00000004066(DPYS),ENSXETG00000012718(dpysl3),ENSXETG00000023585(dpysl4)" "ENSMUSG00000022304(Dpys),ENSMUSG00000024501(Dpysl3),ENSMUSG00000022048(Dpysl2),ENSMUSG00000029121(Crmp1),ENSMUSG00000025478(Dpysl4)" "ENSG00000147647(DPYS),ENSG00000092964(DPYSL2),ENSG00000113657(DPYSL3),ENSG00000072832(CRMP1),ENSG00000157851(DPYSL5),ENSG00000151640(DPYSL4)" "chemical sensitive,viable,fertile,memory defective,circadian behavior defective,recessive" "external sensory organ precursor cell I,somatic clone,centrosome | somatic clone,centrosomeneur-P72" FBgn0010637 l(2)07206 lethal (2) 07206 http://flybase.net/reports/FBgn0010637.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001579 l(1)AL1 lethal (1) AL1 http://flybase.net/reports/FBgn0001579.html gene 16-Dec-15 2015_12 "lethal,short lived" FBgn0060700 l(3)S071802b lethal (3) S071802b http://flybase.net/reports/FBgn0060700.html gene 0718/02 16-Dec-15 2015_12 "lethal,recessive" FBgn0003174 pwn pawn http://flybase.net/reports/FBgn0003174.html FBgn0033157 protein_coding_gene 0005509=calcium ion binding "0046331=lateral inhibition, 0007602=phototransduction, 0008407=chaeta morphogenesis" "l(2)pwn, pawn, CG11101, N-like, CT31067, Pawn" "IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR001881=EGF-like calcium-binding domain, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site" CG11101 16-Dec-15 2015_12 "viable,fertile,neurophysiology defective,partially lethal - majority die,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,germline clone" "chaeta,eye,microvillus & rhabdomere | distal,retina,macrochaeta,cornea" FBgn0037824 CG14684 http://flybase.net/reports/FBgn0037824.html protein_coding_gene 0051726=regulation of cell cycle CG14684 16-Dec-15 2015_12 viable FBgn0260613 2L2366 http://flybase.net/reports/FBgn0260613.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 viable "dorsal air sac primordium,somatic clone" FBgn0001030 Fs(3)Ber Female sterile (3) Bercel http://flybase.net/reports/FBgn0001030.html gene "Fs(3)Sz4, Fs(3)Bercel" 16-Dec-15 2015_12 "visible,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0003520 stau staufen http://flybase.net/reports/FBgn0003520.html protein_coding_gene "0003729=mRNA binding, 0003725=double-stranded RNA binding, 0003730=mRNA 3'-UTR binding, 0008017=microtubule binding" "0055059=asymmetric neuroblast division, 0007318=pole plasm protein localization, 0045450=bicoid mRNA localization, 0046011=regulation of oskar mRNA translation, 0007317=regulation of pole plasm oskar mRNA localization, 0046012=positive regulation of oskar mRNA translation, 0019094=pole plasm mRNA localization, 0045451=pole plasm oskar mRNA localization, 0010606=positive regulation of cytoplasmic mRNA processing body assembly, 0007316=pole plasm RNA localization, 0006403=RNA localization, 0008595=anterior/posterior axis specification, embryo, 0007315=pole plasm assembly, 0008298=intracellular mRNA localization, 0045167=asymmetric protein localization involved in cell fate determination, 0048477=oogenesis, 0007017=microtubule-based process, 0008104=protein localization, 0007616=long-term memory, 0007400=neuroblast fate determination" "0045179=apical cortex, 0005737=cytoplasm, 0045180=basal cortex, 0045177=apical part of cell, 0000932=cytoplasmic mRNA processing body, 0009925=basal plasma membrane, 0005938=cell cortex, 0005875=microtubule associated complex, 0016324=apical plasma membrane" "Stauffen, STAU, Stau, dStau, Staufen, CG5753, Dmstau, Stauf, STAUFEN" IPR014720=Double-stranded RNA-binding domain CG5753 16-Dec-15 2015_12 "ENSDARG00000044182(stau1),ENSDARG00000026801(stau2)" WBGene00018857(stau-1) "ENSXETG00000001783(TTpA004b17.1),ENSXETG00000011826(BC088555.1)" "ENSG00000040341(STAU2),ENSG00000124214(STAU1)" " adult stage && oogenesis stage | stage S6 , adult stage && oogenesis stage | stage S6-10 , adult stage && oogenesis stage | stage S3-4 , egg stage | fertilized egg " " oocyte | presumptive

, nurse cell

, female germline stem cell

, fertilized egg | ubiquitous

" " embryonic stage | stage 13 , oogenesis stage | stage S6-8 , oogenesis stage | stage S3-4 , embryonic stage | stage 1 , adult stage && oogenesis stage | stage >=S10B , adult stage && oogenesis stage | stage S10 , embryonic stage | extended germ band , embryonic stage | early , adult stage , adult stage && oogenesis stage | stage S8-10B " " central nervous system

, polar follicle cell

posterior , oocyte | presumptive

,

terminal , nurse cell

, organism | 90-100% egg length

, oocyte | posterior

, embryonic nervous system

, organism | anterior

, pole plasm

, stage S11 oocyte | anterior

, organism | posterior

, organism | 0-10% egg length

" "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,germline clone,non-rescuable maternal effect,wild-type,memory defective,heat sensitive,lethal,male sterile,female sterile,grandchildless,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,somatic clone" "embryonic head,maternal effect,embryonic abdomen,germline clone,embryo,posterior,pole cell,abdominal segment,pole granule,embryonic abdominal segment,cephalic furrow,anterior,pole plasm,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,RP2 motor neuron,somatic clone" FBgn0004691 rss reduced scutellars and sternitals http://flybase.net/reports/FBgn0004691.html gene 16-Dec-15 2015_12 "scutellar bristle,sternite" FBgn0001822 l(1)tl lethal (1) tracheae lacking http://flybase.net/reports/FBgn0001822.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0004865 Eip78C Ecdysone-induced protein 78C http://flybase.net/reports/FBgn0004865.html "FBgn0046387, FBgn0046388" protein_coding_gene "0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding, 0003707=steroid hormone receptor activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0043401=steroid hormone mediated signaling pathway, 0006355=regulation of transcription, DNA-templated, 0002165=instar larval or pupal development" 0005634=nucleus "Eip78D, Eip 78C, nuclear hormone receptor, dE78, NR1E1, DR-78, E78A, anon-WO0172774.44, ecdysone induced protein 78C, E78D, CG18023, E78, EIP78C, E78B, anon-WO0172774.42, Eip78" "IPR013088=Zinc finger, NHR/GATA-type, IPR001723=Nuclear hormone receptor, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG18023 16-Dec-15 2015_12 "ENSDARG00000003820(nr1d2a),ENSDARG00000009594(nr1d2b),ENSDARG00000033160(nr1d1),ENSDARG00000031161(nr1d4a),ENSDARG00000059370" WBGene00004786(sex-1) "ENSXETG00000024397(NR1D1),ENSXETG00000003869(NR1D2)" "ENSMUSG00000021775(Nr1d2),ENSMUSG00000020889(Nr1d1)" "ENSG00000126368(NR1D1),ENSG00000174738(NR1D2)" " larval stage | 32-48 hr , L | third instar stage 2-- P | stage P4 , larval stage | third instar stage 2-- P | stage P4 , pupal stage | 48-56 hr , third instar larval stage L2-- prepupal stage | stage P4 , larval stage | third instar stage 2--P | stage P4 " organism

"viable,fertile,female fertile,male fertile,visible,partially lethal - majority die,some die during pupal stage" "ommatidium,eye,dorsal appendage" FBgn0011241 cbx crossbronx http://flybase.net/reports/FBgn0011241.html FBgn0033456 protein_coding_gene 0004842=ubiquitin-protein transferase activity "0042742=defense response to bacterium, 0007291=sperm individualization, 0007286=spermatid development, 0016567=protein ubiquitination" "ms(2)46C, CG10536, male sterile(2)46C, ms(2)05704, Ft1, Cbx" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG10536 16-Dec-15 2015_12 ENSDARG00000026862(aktip) WBGene00006714(ubc-19) ENSXETG00000008091(fts) ENSMUSG00000031667(Aktip) ENSG00000166971(AKTIP) "viable,fertile,male sterile,recessive,neuroanatomy defective,somatic clone" "spermatid,crystal cell,spermatozoon,primary spermatocyte cyst,spermatid & nucleus,neuroblast,somatic clone" FBgn0001522 l(1)11Da lethal (1) 11Da http://flybase.net/reports/FBgn0001522.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone" FBgn0028639 ifm(2)RU3 indirect flight muscle (2) RU3 http://flybase.net/reports/FBgn0028639.html gene "0060361=flight, 0007527=adult somatic muscle development, 0007517=muscle organ development" 0005703=polytene chromosome puff 16-Dec-15 2015_12 "visible,recessive,flight defective,fertile,viable,reduced,lethal,flightless" "wing,dorsal medial muscle,indirect flight muscle" FBgn0027963 l(3)S145709 lethal (3) S145709 http://flybase.net/reports/FBgn0027963.html gene 1457/09 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069318 X-183-12 X-183-12 http://flybase.net/reports/FBgn0069318.html gene 0016331=morphogenesis of embryonic epithelium 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,recessive,rescuable maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0037783 Npc2c Niemann-Pick type C-2c http://flybase.net/reports/FBgn0037783.html protein_coding_gene 0032934=sterol binding "0022008=neurogenesis, 0015918=sterol transport" "npc2c, DmML5A, CG3934" "IPR003172=MD-2-related lipid-recognition domain, IPR014756=Immunoglobulin E-set" CG3934 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0061198 HSPC300 http://flybase.net/reports/FBgn0061198.html FBgn0050173 protein_coding_gene "0010592=positive regulation of lamellipodium assembly, 0021551=central nervous system morphogenesis, 0008582=regulation of synaptic growth at neuromuscular junction, 0008360=regulation of cell shape, 0051259=protein oligomerization, 0051491=positive regulation of filopodium assembly" "HSPC300, CG30173, Syntaxin Interacting Protein 1, dHSPC, SIP1, Brk1" CG30173 16-Dec-15 2015_12 ENSDARG00000041974(zgc:86903) ENSXETG00000027883() ENSMUSG00000033940(6720456B07Rik) ENSG00000219870 "lethal,recessive,maternal effect,neuroanatomy defective,dominant,partially,viable,cell shape defective,visible,planar polarity defective" "presumptive embryonic/larval central nervous system,maternal effect,longitudinal connective,ventral nerve cord commissure,embryonic/larval neuromuscular junction,mesothoracic bristle,chaeta,supernumerary" DRSC22880 I 1.547867006 0.220774459 -0.241300541 0.077786401 -0.005323899 -0.225236162 FBgn0004901 Prat Phosphoribosylamidotransferase http://flybase.net/reports/FBgn0004901.html protein_coding_gene 0004044=amidophosphoribosyltransferase activity "0006189='de novo' IMP biosynthetic process, 0040016=embryonic cleavage, 0008340=determination of adult lifespan, 0048477=oogenesis, 0009113=purine nucleobase biosynthetic process" "CG2867, DmPrat, transcript D" "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR017932=Glutamine amidotransferase type 2 domain, IPR029057=Phosphoribosyltransferase-like, IPR005854=Amidophosphoribosyltransferase" CG2867 16-Dec-15 2015_12 ENSDARG00000004517(ppat) YMR300C(ADE4) WBGene00011407(T04A8.5) ENSXETG00000005618(Q6P2Z4_XENTR) ENSMUSG00000029246(Ppat) ENSG00000128059(PPAT) "lethal,recessive,partially lethal - majority die,visible,aging defective,dominant,female,partially,short lived,conditional,maternal effect,melanotic necrosis,increased cell death,some die during pupal stage,female sterile,viable" "posterior crossvein,follicle cell,border follicle cell,nurse cell & nucleus,oocyte,egg chamber,cycle 6 embryo,maternal effect,cycle 7 embryo,cycle 8 embryo,cycle 9 embryo,cycle 10 embryo,cycle 11 embryo,cycle 12 embryo,cycle 13 embryo,polar body nucleus,yolk nucleus,cleavage nucleus,nurse cell & nucleusdsx43),embryonic abdominal segment,larval abdominal segment,wing,leg,wing disc,tergite | pharate adult stage" FBgn0000721 for foraging http://flybase.net/reports/FBgn0000721.html "FBgn0000443, FBgn0010629, FBgn0031555, FBgn0044607, FBgn0063202, FBgn0066013" protein_coding_gene "0004690=cyclic nucleotide-dependent protein kinase activity, 0004692=cGMP-dependent protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0008016=regulation of heart contraction, 0032095=regulation of response to food, 0009744=response to sucrose, 0030536=larval feeding behavior, 0007616=long-term memory, 0007631=feeding behavior, 0046959=habituation, 0008345=larval locomotory behavior, 0007614=short-term memory" "0005886=plasma membrane, 0005829=cytosol" "FOR/PKG, Pkg24A, PKG, CG10033, dg2, Dg2, Pkg2, anon-WO02059370.47, For, 142251_at, DG2, BcDNA:GM08338, l(2)06860, anon-WO0140519.260" "IPR011009=Protein kinase-like domain, IPR014710=RmlC-like jelly roll fold, IPR000719=Protein kinase domain, IPR018488=Cyclic nucleotide-binding, conserved site, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR018490=Cyclic nucleotide-binding-like, IPR000961=AGC-kinase, C-terminal, IPR000595=Cyclic nucleotide-binding domain, IPR002374=cGMP-dependent kinase, IPR008271=Serine/threonine-protein kinase, active site" CG10033 16-Dec-15 2015_12 ENSDARG00000020656(prkg1a) ENSMUSG00000052920(Prkg1) ENSG00000185532(PRKG1) "learning defective,lethal,wild-type,chemical resistant,heat sensitive,recessive,viable,fertile,dominant,hyperactive,behavior defective,neurophysiology defective,semidominant,memory defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,hypoactive,short lived,RU486 conditional,locomotor behavior defective,visible,partially lethal - majority die" "crystal cell,adult heart,axon terminus | larval stage,embryonic/larval tracheal system,adult Malpighian tubule,mesothoracic tergum" DRSC00195 I -0.864213044 -1.521181525 -0.542813679 0.130915826 0.639699844 0.586525244 FBgn0005558 ey eyeless http://flybase.net/reports/FBgn0005558.html "FBgn0000616, FBgn0004525, FBgn0004547, FBgn0010156" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0005515=protein binding" "0030182=neuron differentiation, 0006357=regulation of transcription from RNA polymerase II promoter, 0008347=glial cell migration, 0048749=compound eye development, 0001745=compound eye morphogenesis, 0008284=positive regulation of cell proliferation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007455=eye-antennal disc morphogenesis, 0048854=brain morphogenesis, 0030307=positive regulation of cell growth, 0016319=mushroom body development, 0043704=photoreceptor cell fate specification, 0048036=central complex development, 0045893=positive regulation of transcription, DNA-templated, 0007420=brain development, 0007628=adult walking behavior, 0043567=regulation of insulin-like growth factor receptor signaling pathway, 0006355=regulation of transcription, DNA-templated, 0040018=positive regulation of multicellular organism growth" "0005634=nucleus, 0005667=transcription factor complex" "tumor-head-63, Pax6, EY, Ey/Pax6, Eyeless, l(4)102CDh, eye, Pax-6, l(4)33, DPax-6, EYEL, CG1464, l(4)102CDr, pax6, OK107, Ey" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001523=Paired domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG1464 16-Dec-15 2015_12 "ENSDARG00000045936(pax6b),ENSDARG00000045045(pax6a)" WBGene00006870(vab-3) ENSXETG00000008175(PAX6) " embryonic stage | stage 9-11 , pupal stage , embryonic stage , embryonic stage -- adult stage , embryonic stage | stage 9-10 , larval stage | third instar , embryonic stage | stage 12 , adult stage , embryonic stage | stage 16-17 " " tritocerebral neuroblast | subset

, eye-antennal disc | primordium

, protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | restricted

, eye-antennal disc | anterior

, Bolwig's organ

, procephalic neurogenic region && embryonic antennal segment | restricted

, adult head

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic intercalary segment | restricted

, embryonic central nervous system

" " embryonic stage | stage 9-11 , embryonic stage | stage 9-10 " " procephalic neurogenic region && embryonic intercalary segment | restricted

, protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic antennal segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | restricted

, tritocerebral neuroblast | subset

" "viable,increased cell death,lethal,partially,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,neuroanatomy defective,locomotor behavior defective,small body,decreased cell size,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,eye color defective" "neuropil & mushroom body & pupa,ellipsoid body,adult mushroom body,eye,ectopic,antenna,eye disc,eye-antennal disc,ommatidium,medial branch of mushroom body,optic lobe,retina,Kenyon cell,medulla,somatic clone,embryonic/larval optic lobe,adult head,head,heat sensitive,gena,vibrissae,anterior vertical bristle,posterior vertical bristle,photoreceptor cell,lamina anlage glial cell,subretinal glial cell,adult central complex,adult brain,lamina,cell body rind of medulla,serpentine layer,lobula,lobula plate,fan-shaped body,protocerebral bridge,mushroom body & neuron,lobe system of adult mushroom body,calyx of adult mushroom body,wing,adult pars intercerebralis,median bundle,neurite,maxillary palpus,third segment of antenna,arista,embryonic/larval hemolymph,eye | pharate adult stage,wing disc,wing hinge,antennal disc & eye | ectopicdpp.blk1,ventral thoracic disc & eye | ectopicdpp.blk1,proboscis & ommatidium | ectopicdpp.blk1,haltere & ommatidium | ectopicdpp.blk1,leg,proximal,haltere,leg & eye | ectopicdpp.blk1,eye photoreceptor cell | ectopic & antennal discdpp.blk1,eye photoreceptor cell & dorsal mesothoracic disc | ectopicdpp.blk1,eye photoreceptor cell & ventral thoracic disc | ectopicdpp.blk1,photoreceptor,ectopic | third instar larval stage,wing & eye | ectopicupd-E132,leg & eye | ectopicupd-E132,antenna & eye | ectopicupd-E132,haltere & eye | ectopicupd-E132,posterior,anterior/posterior compartment boundary,tibia,head bristle,neuron,haltere disc,ventral thoracic disc,wing & eye | ectopicMS941,vertical branch of mushroom body,vertical lobe of adult mushroom body,ventral nerve cord,commissure,longitudinal connective,intersegmental nerve,segmental nerve,glial cell,embryonic brain,embryonic central brain neuron,tritocerebral commissure,circumesophageal tract,rhabdomerelz-gal4" FBgn0015279 Pi3K92E Pi3K92E http://flybase.net/reports/FBgn0015279.html FBgn0014938 protein_coding_gene "0017124=SH3 domain binding, 0016303=1-phosphatidylinositol-3-kinase activity, 0046934=phosphatidylinositol-4,5-bisphosphate 3-kinase activity, 0001727=lipid kinase activity, 0035005=1-phosphatidylinositol-4-phosphate 3-kinase activity, 0035004=phosphatidylinositol 3-kinase activity" "0060074=synapse maturation, 0002168=instar larval development, 0048813=dendrite morphogenesis, 0035264=multicellular organism growth, 0006914=autophagy, 0008286=insulin receptor signaling pathway, 0045927=positive regulation of growth, 0046620=regulation of organ growth, 0005975=carbohydrate metabolic process, 0006629=lipid metabolic process, 0045727=positive regulation of translation, 0002164=larval development, 0006979=response to oxidative stress, 0051124=synaptic growth at neuromuscular junction, 0007390=germ-band shortening, 0048477=oogenesis, 0050773=regulation of dendrite development, 0048169=regulation of long-term neuronal synaptic plasticity, 0051823=regulation of synapse structural plasticity, 2000377=regulation of reactive oxygen species metabolic process, 0040014=regulation of multicellular organism growth, 0045793=positive regulation of cell size, 0009267=cellular response to starvation, 0036335=intestinal stem cell homeostasis, 0055115=entry into diapause, 0046854=phosphatidylinositol phosphorylation, 0007436=larval salivary gland morphogenesis, 0016310=phosphorylation, 0042127=regulation of cell proliferation, 0045572=positive regulation of imaginal disc growth, 0007552=metamorphosis, 0030307=positive regulation of cell growth, 0048015=phosphatidylinositol-mediated signaling, 0010507=negative regulation of autophagy, 0016049=cell growth, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0016322=neuron remodeling, 0030536=larval feeding behavior, 0007346=regulation of mitotic cell cycle, 0008361=regulation of cell size, 0046622=positive regulation of organ growth" "0005943=phosphatidylinositol 3-kinase complex, class IA" "Pi3K92D, dPI3K[92E], PI3Kinase92E, Pi3K, dP13K, rea, PI-3 kinase, PiK92E, Phosphoinositide-3 Kinase, type-1 PI3K, DP110, Pi3K92E|p110, phosphoinositide 3-kinase, dp110alpha, PI3-kinase, phosphatidylinositol 3-kinase, phosphatidylinositol-3 kinase, PI[[3]]K, Phosphotidylinositol 3 kinase, Phosphatidylinositol-3-kinase, PI3'K, Pi3k, CG4141, p110 PI3 kinase, anon-92Ed, dp110, dPI3K, PI3K-92E/Dp110, Dp110, Dpp110, PI3K, insulin-regulated PI3 kinase, PI3 kinase, pi3k92e, phosphoinositide 3 kinase Dp110, PI3k, p120, dP110, PI3K-dp110, dPI 3-kinase, PI(3)K, PI3K-92D, Pi3Kp110, phospho-inositol-3 kinase at 92E, PI 3-kinase, PI3K92E, PI3K-Dp110, PI-3-K, Dmp110, class I PI(3)K, p110, Dp110/PI3K" "IPR003113=Phosphatidylinositol 3-kinase adaptor-binding (PI3K ABD) domain, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR029071=Ubiquitin-related domain, IPR000008=C2 domain, IPR001263=Phosphoinositide 3-kinase, accessory (PIK) domain, IPR002420=Phosphatidylinositol 3-kinase, C2 domain, IPR011009=Protein kinase-like domain, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR000341=Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain, IPR016024=Armadillo-type fold, IPR015433=Phosphatidylinositol Kinase" CG4141 16-Dec-15 2015_12 ENSDARG00000003250(pik3cd) WBGene00000090(age-1) ENSXETG00000008254(PIK3CB) "ENSMUSG00000039936(Pik3cd),ENSMUSG00000032462(Pik3cb)" "ENSG00000051382(PIK3CB),ENSG00000171608(PIK3CD)" "wild-type,small body,somatic clone,lethal,viable,recessive,planar polarity defective,decreased cell size,neurophysiology defective,visible,chemical resistant,heat sensitive,neuroanatomy defective,size defective,decreased cell number,cell autonomous,cell non-autonomous,large body,cell size defective,developmental rate defective,increased cell number,wound healing defective,locomotor behavior defective,cell death defective,smell perception defective,long lived,RU486 conditional,semi-sterile,short lived,chemical sensitive,increased cell growth,increased cell size,hyperplasia,feeding behavior defective,cell growth defective,stress response defective,fertile,partially lethal - majority die,some die during pupal stage,some die during larval stage,photoperiod response variant,decreased cell death,starvation stress response defective,decreased cell growth,female sterile" "egg chamber,germline clone,fat body,larva,imaginal disc,ommatidium,somatic clone,embryo,embryonic leading edge cell,head capsule,wing,embryonic/larval neuromuscular junction | third instar larval stage,wing blade,embryonic/larval neuroblast,dorsal multidendritic neuron ddaC | pupal stage,dendrite | larval stageppk.PG,1st posterior cell,eye,synapse,chaeta,mesothoracic tergum,wing & celldpp.blk1,prothoracic gland,wing disc,posterior compartment,imaginal disc & cell,germ band,neuron,supernumerary,embryonic/first instar larval cuticle,antennal lobe,synapseGH298,intrinsic neuron,synapsekra-krasavietz,antennal lobe glomerulus DM2,synapseGH298, kra-krasavietz,synapseMef2.247,adult mushroom body,synapseD42,axonD42,motor neuron,bouton,synapseC57,adult gut,heat sensitive,RU486 conditional,interommatidial bristle,somatic clone | third instar larval stage,embryonic/larval fat body,embryo | dorsal closure stage,embryonic/larval peripheral nervous system | third instar larval stage,plasmatocyte,ectopic,mitotic cell cycle | somatic clone,ommatidial precursor cluster,eye disc,embryonic/larval digestive system,embryonic/larval Malpighian tubule,embryonic/larval epidermis,cell surface & nurse cell | somatic clone,posterior,ring canal,embryonic/larval salivary gland,puparium,lysosomeLsp2.PH,autophagic vacuoleLsp2.PH,ellipsoid body,synapse | supernumerary796,dendrite796,embryonic/larval neuromuscular junction,synapse | supernumeraryD42,dendritesmid-C161,cell bodysmid-C161,dorsal multidendritic neuron ddaC,neuropil,dendrite | somatic cloneVGlut-OK371,cell body | somatic cloneVGlut-OK371,gastric caecum,embryonic/larval fat body | third instar larval stage,autolysosome | third instar larval stage,embryonic/larval gut | third instar larval stage,ovary" FBgn0032901 sky skywalker http://flybase.net/reports/FBgn0032901.html "FBgn0032902, FBgn0041002, FBgn0061988" protein_coding_gene 0005096=GTPase activator activity "0007274=neuromuscular synaptic transmission, 0007268=synaptic transmission, 1903422=negative regulation of synaptic vesicle recycling, 0043087=regulation of GTPase activity" "0031594=neuromuscular junction, 0043195=terminal bouton" "CG14399, anon-WO0118547.455, CG9340, CG9339" "IPR000195=Rab-GTPase-TBC domain, IPR006571=TLDc domain" CG9339 16-Dec-15 2015_12 WBGene00016292(tbc-7) "ENSXETG00000019537(),ENSXETG00000020284(TBC1D24)" ENSMUSG00000036473(Tbc1d24) ENSG00000162065(TBC1D24) "some die during pupal stage,neurophysiology defective,lethal - all die before end of pupal stage,lethal,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable" "embryonic/larval neuromuscular junction,neuromuscular junction" DRSC03215 IE -0.666370575 1.587509982 -1.63347697 2.520195685 0.130835993 -0.00250038 FBgn0027633 ms(1)280 ms(1)280 http://flybase.net/reports/FBgn0027633.html gene 16-Dec-15 2015_12 male sterile FBgn0260591 2L3298 http://flybase.net/reports/FBgn0260591.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0050325 CG30325 http://flybase.net/reports/FBgn0050325.html protein_coding_gene CG30325 16-Dec-15 2015_12 viable FBgn0036126 CG6272 http://flybase.net/reports/FBgn0036126.html FBgn0063258 protein_coding_gene "0046982=protein heterodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" "BcDNA:GH10915, DM10, CT19628" "IPR031106=CCAAT/enhancer-binding protein C/EBP, IPR004827=Basic-leucine zipper domain" CG6272 16-Dec-15 2015_12 WBGene00016754(C48E7.11) ENSXETG00000027337(cebpg) ENSMUSG00000056216(Cebpg) ENSG00000153879(CEBPG) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC10612 E -0.239751538 0.212987481 -0.145804849 1.8747706 -0.990761968 1.115964596 FBgn0014007 Ptp69D Protein tyrosine phosphatase 69D http://flybase.net/reports/FBgn0014007.html protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0005001=transmembrane receptor protein tyrosine phosphatase activity, 0004728=receptor signaling protein tyrosine phosphatase activity" "0008045=motor neuron axon guidance, 0007411=axon guidance, 0006470=protein dephosphorylation, 0046331=lateral inhibition, 0007414=axonal defasciculation, 0007415=defasciculation of motor neuron axon, 0048813=dendrite morphogenesis, 0097155=fasciculation of sensory neuron axon" "0030424=axon, 0005886=plasma membrane" "R-PTP 69D, Ptp69d, DPTP, Dptp69D, dptp69D, PTP69D, ptp69d, PTPase, 69D, CT30751, protein tyrosine phosphatase PTP69D, Ptp, DPTP69D, CG10975, dptp69d, ptp69D" "IPR000242=PTP type protein phosphatase, IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR029021=Protein-tyrosine phosphatase-like, IPR013783=Immunoglobulin-like fold, IPR016130=Protein-tyrosine phosphatase, active site, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG10975 16-Dec-15 2015_12 larval stage | third instar " lamina plexus | anterior

, medulla neuropil

, lamina neuropil

, larval optic neuropil

" "neuroanatomy defective,wild-type,lethal,partially,heat sensitive,viable,recessive,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective,body color defective,visible" "dendritic arborizing neuron,axon,dendrite,photoreceptor cell & axon | somatic clone,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,medulla,somatic clone,RP neuron & axon,central nervous system,abdominal segmental nerve,intersegmental nerve,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina plexus,glial cell & lamina,mesothoracic tergum,chaeta,supernumerary" DRSC11258 K 1.101237795 -0.227048802 1.034879981 -0.472699704 3.452830469 0.743735015 FBgn0051774 fred friend of echinoid http://flybase.net/reports/FBgn0051774.html "FBgn0031577, FBgn0031578, FBgn0040709" protein_coding_gene "0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0035018=adult chitin-based cuticle pattern formation, 0001745=compound eye morphogenesis, 0007423=sensory organ development" "CG3390, CG3393, Friend of Echinoid, CT11413, CG12675, CG31774, Fred" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR013151=Immunoglobulin" CG31774 16-Dec-15 2015_12 WBGene00018215(igcm-1) " embryonic stage , larval stage | third instar " " organism

, eye disc

ubiquitous , dorsal mesothoracic disc

ubiquitous " "increased cell death,viable" "ommatidium,somatic clone,ommatidial precursor cluster,adult cuticle,mesothoracic tergum,scutellum,macrochaeta,ectopic,dorsal mesothoracic disc & sensory mother cell | dorsal | ectopicpnr-MD237,eye,dorsal mesothoracic disc & sensory mother cell | ectopicap-md544" FBgn0001320 kni knirps http://flybase.net/reports/FBgn0001320.html "FBgn0003253, FBgn0017615" protein_coding_gene "0070491=repressing transcription factor binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0005515=protein binding, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048813=dendrite morphogenesis, 0045892=negative regulation of transcription, DNA-templated, 0035151=regulation of tube size, open tracheal system, 0008544=epidermis development, 0007354=zygotic determination of anterior/posterior axis, embryo, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007427=epithelial cell migration, open tracheal system, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0035290=trunk segmentation, 0007517=muscle organ development, 0007088=regulation of mitotic nuclear division, 0007424=open tracheal system development" 0005634=nucleus "Kn, CG4717, Kni, knr, NR0A1, KNIRPS, ri, radius incompletus, KNI, kn, Knirps" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR013088=Zinc finger, NHR/GATA-type" CG4717 16-Dec-15 2015_12 " embryonic stage | cellular blastoderm , embryonic stage | stage 4 , embryonic stage , embryonic stage | early , larval stage | third instar , embryonic stage | blastoderm " "

30-50% egg length ,

20-40% egg length ,

anterior , wing vein L2 | precursor

,

70-100% egg length , organism | 30-50% egg length

" "viable,fertile,wild-type,visible,heat sensitive,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,embryonic/larval segmentation phenotype,dominant,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal branch primordium,wing vein,heat sensitive,wing,ectopic,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,abdomen,wing vein L2,mesothoracic ventral denticle belt,mesothoracic segment,ventral,distal,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,extended germ band embryo,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 2,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 4,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 6,embryonic/first instar larval cuticle & abdominal segment 7,macrophage,embryo,abdominal segment,embryonic/larval dorsal anastomosis,adherens junction & embryonic dorsal trunkbtl.PS,dorsal trunk primordium,metathoracic femur,adult thorax & macrochaetaBx-MS1096" FBgn0001083 fw furrowed http://flybase.net/reports/FBgn0001083.html protein_coding_gene 0030246=carbohydrate binding "0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0042067=establishment of ommatidial planar polarity, 0035317=imaginal disc-derived wing hair organization, 0007423=sensory organ development, 0050821=protein stabilization, 0007476=imaginal disc-derived wing morphogenesis" 0043296=apical junction complex "CT3745, Furrowed, wrinkled, CG1500, fw-like, wr" "IPR008979=Galactose-binding domain-like, IPR006585=Fucolectin tachylectin-4 pentraxin-1, IPR000436=Sushi/SCR/CCP domain, IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold, IPR000421=Coagulation factor 5/8 C-terminal domain" CG1500 16-Dec-15 2015_12 WBGene00008314(C54G4.4) "ENSXETG00000004772(),ENSXETG00000007710(),ENSXETG00000025787()" "ENSG00000174175(SELP),ENSG00000007908(SELE)" " larval stage | first instar -- larval stage | third instar , embryonic stage -- adult stage " " larval brain | restricted

, embryonic/larval proventriculus | restricted

" larval stage | first instar -- larval stage | third instar " larval brain | restricted

, embryonic/larval proventriculus | restricted

" "viable,visible,lethal,partially,female,planar polarity defective,somatic clone,fertile,wild-type,male fertile,female fertile,male,reduced,eye color defective,sterile,female sterile,recessive,poor,partially lethal - majority live,partially lethal - majority die,some die during pupal stage" "eye,adult head,scutellum,notopleural bristle,macrochaeta,posterior scutellar bristle,retina,ommatidium,interommatidial bristle,microchaeta,eye & macrochaeta,lamina,eye photoreceptor cell,cone cell,pigment cell,chaeta,trichome,wing hair,mesothoracic tergum,scutellar bristle,postalar bristle,wing,arista,scutoscutellar suture,embryonic/larval anal pad,pupal spiracle,ovariole,testis sheath,Malpighian tubule,acrostichal bristle,wing vein,trichogen cell" FBgn0003158 ptg pentagon http://flybase.net/reports/FBgn0003158.html gene "0007608=sensory perception of smell, 0048477=oogenesis" "crown, cro, 3D18, fs(1)M71" 16-Dec-15 2015_12 "smell perception defective,recessive,lethal,visible,female sterile,partially,body color defective" "trident,scutellum" FBgn0260015 trin trinidad http://flybase.net/reports/FBgn0260015.html gene 0030717=karyosome formation 16-Dec-15 2015_12 viable "karyosome,chorion | germline clone" FBgn0014135 bnl branchless http://flybase.net/reports/FBgn0014135.html "FBgn0010906, FBgn0013633" protein_coding_gene "0008083=growth factor activity, 0005104=fibroblast growth factor receptor binding" "0007427=epithelial cell migration, open tracheal system, 0035215=genital disc development, 0007426=tracheal outgrowth, open tracheal system, 0046847=filopodium assembly, 2000274=regulation of epithelial cell migration, open tracheal system, 0006935=chemotaxis, 0001763=morphogenesis of a branching structure, 0000187=activation of MAPK activity, 0007429=secondary branching, open tracheal system, 0008347=glial cell migration, 0050918=positive chemotaxis, 0007424=open tracheal system development, 0008543=fibroblast growth factor receptor signaling pathway, 0007430=terminal branching, open tracheal system, 0035231=cytoneme assembly, 0007428=primary branching, open tracheal system, 0035152=regulation of tube architecture, open tracheal system" 0005576=extracellular region "CG4608, fibroblast growth factor protein, l(3)06916, l(3)neo52, Bnl, BNL, FGF, fibroblast growth factor, DFGF, DmBnl, fibroblast growth factor), Branchless, Fibroblast Growth Factor" "IPR008996=Cytokine, IL-1-like, IPR002209=Fibroblast growth factor family" CG4608 16-Dec-15 2015_12 WBGene00002881(let-756) " embryonic stage , embryonic stage | stage >=11 , larval stage | third instar " " cephalic furrow

, posterior transverse furrow

, tracheal air sac | surrounding

, dorsal mesothoracic disc | anterior/posterior compartment boundary & vicinity of & dorsal & restricted

" "lethal,recessive,cell migration defective,visible,somatic clone,cell adhesion defective,hyperplasia,heat sensitive,viable" "embryonic/larval tracheal system,air sac tracheoblast of dorsal air sac primordium,cell non-autonomous,somatic clone,embryonic/larval trachea,lateral H branch,lateral G branch,embryonic/larval ganglionic branch,presumptive embryonic/larval tracheal system,tracheal metamere 1,tracheal metamere 2,tracheal metamere 3,tracheal metamere 4,tracheal metamere 5,tracheal metamere 6,tracheal metamere 7,tracheal metamere 8,tracheal metamere 9,tracheal metamere 10,ganglionic branch primordium,embryonic/larval dorsal trunk,eye,subretinal glial cell,ommatidium,actin cytoskeleton | pupal stage | somatic clone,tracheal system,air sac tracheoblast of dorsal mesothoracic disc & filopodium,dorsal air sac primordium,heat sensitive,air sac tracheoblast of dorsal mesothoracic disc & filopodium | somatic clone | cell non-autonomous,trachea,embryonic tracheal system & filopodium | ectopicbtl.PS,embryonic/larval dorsal branch,embryonic/larval lateral trunk,visceral branch,tracheal tip cell | embryonic stage,pupal abdominal trachea,tracheal metamere" FBgn0030057 Ppt1 Palmitoyl-protein thioesterase 1 http://flybase.net/reports/FBgn0030057.html protein_coding_gene "0098599=palmitoyl hydrolase activity, 0008474=palmitoyl-(protein) hydrolase activity" "0006897=endocytosis, 0002084=protein depalmitoylation, 0098734=macromolecule depalmitoylation, 1902667=regulation of axon guidance, 1900244=positive regulation of synaptic vesicle endocytosis, 0048665=neuron fate specification, 0008340=determination of adult lifespan" 0005764=lysosome "DmPpt1, Palmitoyl-protein Thioesterase 1, PPT1, CG12108, Palmitoyl Protein Thioesterase 1, ppt1, palmitoyl-protein thioesterase 1" "IPR002472=Palmitoyl protein thioesterase, IPR029058=Alpha/Beta hydrolase fold, IPR030294=Palmitoyl-protein thioesterase 1" CG12108 16-Dec-15 2015_12 ENSDARG00000039980(ppt1) WBGene00004092(ppt-1) ENSXETG00000001183(ppt1) ENSMUSG00000028657(Ppt1) ENSG00000131238(PPT1) " adult stage , embryonic stage | 0-18hr , larval stage | third instar , pupal stage , " " adult thorax

, adult head

, testis

, ovary

,

" " larval stage | third instar , pupal stage , adult stage , , embryonic stage | 0-18hr " " adult head

, testis

, adult thorax

,

, ovary

" "lethal,partially,visible,increased cell death,neuroanatomy defective,short lived,recessive,locomotor behavior defective,neurophysiology defective,endocytosis defective,viable" "rhabdomere of eye photoreceptor cell,eye,eye photoreceptor cell,ommatidium,adult brain,ganglion mother cell GMC4-2a,RP2 motor neuron,RP2sib neuron,aCC neuron,supernumerary,pCC neuron,longitudinal connective,midline neuron,ectopic,lch5 neuron,embryonic/larval neuromuscular junction,garland cell" FBgn0001291 Jra Jun-related antigen http://flybase.net/reports/FBgn0001291.html "FBgn0002124, FBgn0015487, FBgn0017591, FBgn0023037" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0005515=protein binding, 0008134=transcription factor binding, 0046982=protein heterodimerization activity" "0006909=phagocytosis, 0006357=regulation of transcription from RNA polymerase II promoter, 0000165=MAPK cascade, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0010259=multicellular organismal aging, 0051124=synaptic growth at neuromuscular junction, 0001736=establishment of planar polarity, 0007465=R7 cell fate commitment, 0007254=JNK cascade, 0046844=micropyle formation, 0008348=negative regulation of antimicrobial humoral response, 0007391=dorsal closure, 0007464=R3/R4 cell fate commitment, 0046843=dorsal appendage formation, 0042060=wound healing, 0046529=imaginal disc fusion, thorax closure, 0045823=positive regulation of heart contraction" "0005634=nucleus, 0005737=cytoplasm, 0005667=transcription factor complex" "d-Jun, AP1, dJra, D-Jun, D-jun, CG2275, dJun, d-JRA, V, cJun, dJUN, l(2R)IA109, JUN, Complementation group V, l(2)IA109, lethal(2)IA109, Jun, jun, jra, activator protein 1, dAP-1, c-Jun, djun, DJUN, AP-1, D-jun/Jra, lethal(2)1A109, d-jun, Djun, JRA, Jun oncogene, DJun, l(2)46Ef, DM14, dm-Jun, Jun related antigen, dJRA" "IPR008917=Transcription factor, Skn-1-like, DNA-binding domain, IPR005643=Jun-like transcription factor, IPR004827=Basic-leucine zipper domain, IPR002112=Transcription factor Jun" CG2275 16-Dec-15 2015_12 "ENSDARG00000067850(jund),ENSDARG00000043531(jun),ENSDARG00000015246,ENSDARG00000036470,ENSDARG00000028415(zgc:153924)" WBGene00000793(crh-1) "ENSXETG00000006441(JUND),ENSXETG00000011124(JUN),ENSXETG00000010199(),ENSXETG00000004766(junb)" "ENSMUSG00000071076(Jund),ENSMUSG00000052684(Jun),ENSMUSG00000052837(Junb)" "ENSG00000130522(JUND),ENSG00000177606(JUN),ENSG00000171223(JUNB)" " embryonic stage , embryonic stage -- adult stage "

ubiquitous " larval stage | third instar , embryonic stage | stage >=12 , embryonic stage " " cone cell

, photoreceptor cell

, morphogenetic furrow | posterior to

, mystery cell

, dorsal ectoderm

, cephalic furrow

, ommatidial precursor cluster

, amnioserosa

" "neurophysiology defective,neuroanatomy defective,somatic clone,visible,dominant,planar polarity defective,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,lethal - all die before end of prepupal stage,some die during prepupal stage,partially lethal - majority die,some die during pupal stage,hypoactive" "adult heart,RU486 conditional,bouton,neuromuscular junction | larval stage,eye,NMJ bouton,somatic clone,embryonic/larval neuromuscular junction,indirect flight muscle motor neuron MN5,dendriteD42, GAL80Cha.3.3P,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,RP2 motor neuron,eye photoreceptor cell,photoreceptor cell R7,cone cell,ommatidium,ectopic,rhabdomere,supernumerary,photoreceptor cell R4,eye disc,ommatidial precursor cluster,embryonic/first instar larval cuticle,heat sensitive,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R5,photoreceptor cell R6,dorsal,embryonic dorsal epidermis,head,epidermis,embryo,anterior,embryonic epidermis,dorsal appendage,maternal effect,micropyle,dorsal closure embryo,midline primordium,photoreceptor cell,commissure,adult thorax,mesothoracic tergum" DRSC07447 IE 3.841476113 1.989327101 2.622856322 1.513888039 -0.2808174 -1.133893617 FBgn0001614 l(1)dd10 lethal (1) discs degenerate 10 http://flybase.net/reports/FBgn0001614.html gene "l(1)d deg-10, l(1)d.deg.10, l(1)d.deg.-10" 16-Dec-15 2015_12 "mitotic cell cycle defective,cell lethal,germline clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0036574 elg1 elg1 homolog http://flybase.net/reports/FBgn0036574.html protein_coding_gene "0022008=neurogenesis, 0048477=oogenesis" CG16838 "IPR003593=AAA+ ATPase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG16838 16-Dec-15 2015_12 ENSDARG00000070568 WBGene00013156(Y53F4B.9) ENSMUSG00000017550(Atad5) ENSG00000176208(ATAD5) "female sterile,viable,visible,lethal,neuroanatomy defective" "nurse cell,macrochaeta,germline clone,embryonic/larval neuroblast" FBgn0052573 CG32573 http://flybase.net/reports/FBgn0052573.html "FBgn0030767, FBgn0040876" protein_coding_gene "Dromel_CG32573_FBtr0074315_mORF, CG4524, CG13013" CG32573 16-Dec-15 2015_12 viable FBgn0005771 noc no ocelli http://flybase.net/reports/FBgn0005771.html "FBgn0001971, FBgn0002947" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding, 0005515=protein binding" "0001752=compound eye photoreceptor fate commitment, 0035214=eye-antennal disc development, 0007424=open tracheal system development, 0008283=cell proliferation, 0006357=regulation of transcription from RNA polymerase II promoter, 0010629=negative regulation of gene expression, 0008056=ocellus development, 0007420=brain development, 0002121=inter-male aggressive behavior, 0035220=wing disc development, 0035218=leg disc development" 0005634=nucleus "Noc, no-ocelli, nocA, el, noc[A], l(2)35Ba/nocA, l35Ba, br22, l(2)35Ba, l(2)br22, CG4491, BG:DS04641.1" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG4491 16-Dec-15 2015_12 "ENSDARG00000018492(znf503),ENSDARG00000035563(znf703),ENSDARG00000067720" WBGene00006580(tlp-1) "ENSXETG00000024347(znf503),ENSXETG00000009866(ZNF503)" ENSMUSG00000039081(Zfp503) "ENSG00000183779(ZNF703),ENSG00000165655(ZNF503)" " embryonic stage | stage 5 , embryonic stage | stage 8-12 , embryonic stage | stage 10-12 , embryonic stage -- adult stage , embryonic stage | stage 5-6 , embryonic stage | stage 8 , embryonic stage | stage 9 " " organism | 90-100% egg length

, labral segment

, stomodeum

, tracheal primordium | surrounding

, ectoderm | stripes

, ventral nerve cord primordium | 50-90% egg length , procephalic segment

, ventral neurogenic region | striped

" "viable,visible,recessive,behavior defective,lethal,lethal - all die before end of larval stage,some die during larval stage" "ocellus,anterior postalar bristle,microchaeta,ocellar bristle,head bristle,postvertical bristle,lateral ocellus,medial ocellus,lateral trunk anterior branch,ganglionic branch primordium,dorsal branch primordium,supraesophageal ganglion,macrochaeta" FBgn0011648 Mad Mothers against dpp http://flybase.net/reports/FBgn0011648.html "FBgn0000105, FBgn0013945, FBgn0022270, FBgn0024356" protein_coding_gene "0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0001102=RNA polymerase II activating transcription factor binding, 0001105=RNA polymerase II transcription coactivator activity, 0003677=DNA binding, 0005515=protein binding, 0030618=transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0007424=open tracheal system development, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0045705=negative regulation of salivary gland boundary specification, 0061353=BMP signaling pathway involved in Malpighian tubule cell chemotaxis, 0035019=somatic stem cell maintenance, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007488=histoblast morphogenesis, 0007507=heart development, 0050803=regulation of synapse structure or activity, 0045595=regulation of cell differentiation, 0007480=imaginal disc-derived leg morphogenesis, 0042078=germ-line stem cell division, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0006357=regulation of transcription from RNA polymerase II promoter, 0030718=germ-line stem cell maintenance, 0001745=compound eye morphogenesis, 0007391=dorsal closure, 0030707=ovarian follicle cell development, 0007476=imaginal disc-derived wing morphogenesis, 0060799=transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification, 0048100=wing disc anterior/posterior pattern formation, 0008586=imaginal disc-derived wing vein morphogenesis, 0035290=trunk segmentation, 0007179=transforming growth factor beta receptor signaling pathway, 0010629=negative regulation of gene expression" "0005667=transcription factor complex, 0005634=nucleus, 0005737=cytoplasm" "E(zen)2, phosphorylated Smad, pMAD, mothers against decapentaplegic, mothers against decapentaplegi, l(2)k00237, Mother against DPP, Mothers against decapentaplegic, apg, CG12399, Mother against Dpp, c28, pSmad, l(2)K00237, 2/23, phospho-Smad, pMad, dMAD, Smad, MAD, apang, Mothers Against Dpp, Mothers against Dpp, Mat, Mother against decapentaplegic, PMad, phosphoSmad, P-mad, mad, dMad, Smad1, Mothers against Decapentaplegic, p-Mad, Mothers against DPP, Mothers against decapentaplegi, Mothers Against Decapentaplegic, P-Mad, mothers against dpp, En(vvl)" "IPR003619=MAD homology 1, Dwarfin-type, IPR017855=SMAD domain-like, IPR013019=MAD homology, MH1, IPR001132=SMAD domain, Dwarfin-type, IPR013790=Dwarfin, IPR008984=SMAD/FHA domain" CG12399 16-Dec-15 2015_12 "ENSDARG00000037238(smad5),ENSDARG00000027199(smad1),ENSDARG00000021938(smad9)" WBGene00004856(sma-2) ENSXETG00000026047(smad1) "ENSMUSG00000031681(Smad1),ENSMUSG00000021540(Smad5),ENSMUSG00000027796(Smad9)" "ENSG00000170365(SMAD1),ENSG00000113658(SMAD5),ENSG00000120693(SMAD9)" embryonic stage -- adult stage embryonic stage

ubiquitous "visible,recessive,sterile,heat sensitive,short lived,RU486 conditional,lethal,neuroanatomy defective,dominant,neurophysiology defective,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,wild-type,viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile,germline clone,rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,small body,mitotic cell cycle defective,cell autonomous,size defective,partially lethal - majority live,increased cell death,conditional" "tarsal segment,heat sensitive,tibia,wing vein L4,wing vein L5,abdominal segment,neuromuscular junction,NMJ bouton,wing,embryonic/larval neuromuscular junction,leg,distal,imaginal disc,photoreceptor cell,somatic clone,eye,embryonic/larval fat body,embryonic/larval optic lobe,embryonic/larval midgut,anterior,testis,germline clone,eye disc,posterior,cell non-autonomous,embryonic/larval dorsal branch,wing disc,eye disc | third instar larval stage,eye-antennal disc,morphogenetic furrow,ommatidium,frons,ectopic,wing vein,wing cell,maternal effect,embryonic/first instar larval cuticle,synapse,t-bar,histoblast,histoblast nest,embryonic/larval somatic muscle,bouton,neuromuscular junctionC28),fat body,denticle belt,female germline stem cell,gastric caecum,embryonic/larval tracheal system,embryonic/larval ventral anastomosis,egg,egg chamber,ovariole,crystal cell,pleurum,male germline stem cell,germarium,wing vein L3,cell autonomous,wing vein L2,tergite,interommatidial bristle,secondary pigment cell,tertiary pigment cell,adult midgut precursor cell,wing margin,ventral,posterior crossvein,wing margin bristle,crossvein,neuromuscular junctionMhc.PW,bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage,wing disc | third instar larval stage,anterior wing margin,temperature conditional,dorsal triple row,wing sensillum,medial triple row,supernumerary,wing pouch,ovary,wing blade" FBgn0041203 LIMK1 LIM-kinase1 http://flybase.net/reports/FBgn0041203.html FBgn0030402 protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0008270=zinc ion binding, 0005524=ATP binding" "0007560=imaginal disc morphogenesis, 0048749=compound eye development, 0048812=neuron projection morphogenesis, 0007416=synapse assembly, 0006468=protein phosphorylation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0051124=synaptic growth at neuromuscular junction, 0050770=regulation of axonogenesis, 0001736=establishment of planar polarity, 0030036=actin cytoskeleton organization" 0005737=cytoplasm "im kinase, Limk, LimK1, LIMK-1, Lim kinase, LimK, D-Limk, LIM Kinase1, limk, LIM-kinase 1, D-LIMK1, dLIMK, dLIMK1, LIM domain protein kinase, Lim Kinase, Lim-kinase, LIM kinase, DLIMK1, Dlimk, CG1848, LIM-DOMAIN KINASE, DLIMK, LIMK, LIM-kinase" "IPR000719=Protein kinase domain, IPR001781=Zinc finger, LIM-type, IPR001478=PDZ domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG1848 16-Dec-15 2015_12 "ENSDARG00000063651(limk1),ENSDARG00000005104(limk2),ENSDARG00000003022" ENSXETG00000010324(LIMK1) "ENSMUSG00000029674(Limk1),ENSMUSG00000020451(Limk2)" "ENSG00000106683(LIMK1),ENSG00000182541(LIMK2)" "neuroanatomy defective,somatic clone,viable,fertile,cell polarity defective,lethal,heat sensitive,visible" "intersegmental nerve branch ISNb of A1-7 | embryonic stage,adult olfactory receptor neuron Or59c,somatic clone,intersegmental nerve branch ISNb of A1-7,wing hair,leg,wing,femur,tibia,wing vein,dorsal mesothoracic disc & actin filamenten-e16E,adult mushroom body,lobe system of adult mushroom body,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,antennal lobe,antennal lobe glomerulus DM6,antennal lobe glomerulus VA6,antennal lobe glomerulus,ectopic" FBgn0062658 EP3283 EP3283 http://flybase.net/reports/FBgn0062658.html gene EP(3)3283 16-Dec-15 2015_12 visible "wing margin bristle,wing vein,supernumerary" FBgn0044826 Pak3 Pak3 http://flybase.net/reports/FBgn0044826.html "FBgn0038430, FBgn0062119" protein_coding_gene "0042803=protein homodimerization activity, 0048365=Rac GTPase binding, 0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" "0007015=actin filament organization, 0051965=positive regulation of synapse assembly, 0007520=myoblast fusion, 0006468=protein phosphorylation, 0046777=protein autophosphorylation" "0001726=ruffle, 0031941=filamentous actin, 0005737=cytoplasm" "pak3, PAK3, dPAK3, DmPAK3, D-Pak3, CG14895, Dpak3, DPak3, DPAK3, anon-WO0118547.285, dpak3, p21-activated kinase 3, PaK3" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000095=CRIB domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG14895 16-Dec-15 2015_12 YHL007C(STE20) "viable,lethal,recessive,neuroanatomy defective,lethal - all die before end of first instar larval stage,lethal - all die before end of larval stage,partially lethal - majority die,partially lethal - majority live,neurophysiology defective,visible" "embryonic/larval cuticle,embryonic myoblast,filamentous actin,embryonic/larval neuromuscular junction,NMJ bouton,microtubuleelav.PU,trichogen cell" DRSC15017 IE 0.490081115 -2.488027712 1.089344813 -1.623929002 -0.376350973 -1.156488887 FBgn0034331 CG15067 http://flybase.net/reports/FBgn0034331.html FBgn0027666 protein_coding_gene 0022008=neurogenesis anon-EST:Posey85 IPR013172=Immune-induced protein Dim CG15067 16-Dec-15 2015_12 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC06502 IE 2.247974115 1.64130564 2.476690802 -0.529705473 -0.049395078 0.079836396 FBgn0026320 Tom Twin of m4 http://flybase.net/reports/FBgn0026320.html "FBgn0025249, FBgn0026264" protein_coding_gene 0005515=protein binding "0001708=cell fate specification, 0016360=sensory organ precursor cell fate determination, 0007219=Notch signaling pathway, 0001736=establishment of planar polarity, 0007423=sensory organ development, 0045746=negative regulation of Notch signaling pathway" 0005737=cytoplasm "CG5185, Barbu, anon-fast-evolving-1F6, barbu, unnamed, tom, anon-EST:fe1F6, DmelCG5185, Twin of M4, Bbu, bbu/tom" IPR029686=Enhancer of split malpha/m4 CG5185 16-Dec-15 2015_12 " embryonic stage | stage 14 , P | stage P4 , embryonic stage | stage 4 , larval stage | third instar , embryonic stage | stage 5 , embryonic stage , embryonic stage | stage 9-12 , larval stage | first instar , embryonic stage | stage 7-11 , embryonic stage | stage 9 , embryonic stage | stage 11 " " lymph gland

, sensillum campaniformium &&of wing

, organism | 90-100% egg length

, morphogenetic furrow | vicinity of

, organism | 0-100% egg length & lateral

, organism | 0-100% egg length & dorsal

, morphogenetic furrow | anterior to

, eye disc

, morphogenetic furrow | posterior to

, ectoderm | restricted

, mesoderm

, ventral neurogenic region

, ventral midline

, embryonic/larval tracheal pit | precursor

, organism | 30-70% egg length

" " embryonic stage , embryonic stage | stage 9 , embryonic stage | blastoderm , embryonic stage | stage 14 , embryonic stage | stage 11 " " mesoderm

, ventral midline

, ventral neurogenic region

, ectoderm | restricted

, lymph gland

, embryonic/larval tracheal pit | precursor

" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,planar polarity defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal,neuroanatomy defective,viable" "macrochaeta,adult head,scutellar bristle,scutum & microchaeta,eye,ommatidium,interommatidial bristle,somatic clone,eye photoreceptor cell,central nervous system,peripheral nervous system,embryonic head,dorsocentral bristle,ectopic,scutum & microchaeta | ectopicpnr-MD237,head bristle,lens,microchaeta,microchaeta & leg-537.4,leg sensillum,external sensory organ precursor cell & dorsal mesothoracic disc-537.4,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,sensory mother cell,supernumerary,sensory neuron,chaeta,secondary neuroblast,apterous-expressing neuron of the lateral cluster of the thorax,orbital bristle,tormogen cell,cardioblast,abdominal 1 dorsal acute muscle 1,A1-7 segment border muscle,embryonic/larval somatic muscle" DRSC27660 K 0.591661259 0.114705723 -0.014509481 0.189382676 -2.187553072 0.165898328 FBgn0013820 Dl::N Dl::N http://flybase.net/reports/FBgn0013820.html engineered_fusion_gene "N, unnamed, Notch intracellular domain" 16-Dec-15 2015_12 "visible,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,cell death defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cell shape defective,somatic clone,lethal" "chordotonal organ precursor cell & ventral thoracic disc-109-68,external sensory organ precursor cell,trichogen cell,photoreceptor cell R8,eye,polar follicle cell,supernumerary,ventral thoracic disc,joint,leg,unguis,wing disc,dorsal compartment,ventral compartment,neuron,EW1 neuron,EW2 neuron,EW3 neuron,GW neuron,ectopic,EW3 neuron | larval stage,embryonic/larval somatic muscle,epidermis,muscle founder cell,presumptive embryonic/larval nervous system,presumptive embryonic/larval central nervous system,embryonic segment,prothoracic metatarsus,prothoracic tarsal segment 3,sex comb,somatic clone,border follicle cell,ventral,eye disc,dorsal,embryonic hindgut,embryonic large intestine,embryonic/larval trachea,embryonic/larval trachea & tracheal tip cellbtl.PS,embryonic/larval dorsal trunk,basal stalk,microtubule109(3)9,abdominal dorsal bipolar neuron dbp,embryonic/larval glial cell,dorsal multidendritic neuron,photoreceptor cell R1,photoreceptor cell R6,oocyte,embryonic/larval optic lobe,temperature conditional,medulla anlage,larval outer optic anlage,male genitalia,secondary neuroblast,supernumerary | third instar larval stage,type II neuroblast" FBgn0035049 Mmp1 Matrix metalloproteinase 1 http://flybase.net/reports/FBgn0035049.html FBgn0022198 protein_coding_gene "0008270=zinc ion binding, 0005509=calcium ion binding, 0004222=metalloendopeptidase activity" "0048102=autophagic cell death, 0007591=molting cycle, chitin-based cuticle, 0042246=tissue regeneration, 0007424=open tracheal system development, 0035001=dorsal trunk growth, open tracheal system, 0007155=cell adhesion, 0006508=proteolysis, 0071711=basement membrane organization, 0035071=salivary gland cell autophagic cell death, 0097156=fasciculation of motor neuron axon, 0042060=wound healing, 0007505=adult fat body development, 0002168=instar larval development, 0035159=regulation of tube length, open tracheal system, 0030198=extracellular matrix organization, 0034769=basement membrane disassembly, 0045216=cell-cell junction organization, 0007561=imaginal disc eversion" "0031012=extracellular matrix, 0030425=dendrite" "l(2)k04809, Dm1-MMP, MMP1, Mmp 1, Matrix Metalloprotinase 1, dmmp1, matrix metalloprotease 1, Matrix metalloproteinase-1, dMMP1, mmp1, metalloproteinase, Matrix metalloprotease 1, matrix metalloprotease, MMP-1, MMp1, Matrix metalloproteinase1, matrix metalloproteinase 1, CG4859, dm1-MMP, Matrix Metalloproteinase 1, matrix metalloproteinase-1" "IPR001818=Peptidase M10, metallopeptidase, IPR018486=Hemopexin, conserved site, IPR002477=Peptidoglycan binding-like, IPR021190=Peptidase M10A, IPR000585=Hemopexin-like domain, IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR016293=Peptidase M10A, stromelysin-type, IPR018487=Hemopexin-like repeats" CG4859 16-Dec-15 2015_12 "ENSDARG00000008388(mmp14b),ENSDARG00000002235(mmp14a)" "ENSXETG00000022669(mmp14),ENSXETG00000013710(MMP16),ENSXETG00000002702(MMP24),ENSXETG00000011375(MMP25)" "ENSMUSG00000000957(Mmp14),ENSMUSG00000031790(Mmp15),ENSMUSG00000028226(Mmp16),ENSMUSG00000027612(Mmp24)" "ENSG00000157227(MMP14),ENSG00000102996(MMP15),ENSG00000156103(MMP16),ENSG00000125966(MMP24)" pupal stage salivary gland

"viable,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,hypoactive,developmental rate defective,some die during third instar larval stage,small body,size defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval fat body,embryonic/larval dorsal trunk,embryonic/larval posterior spiracle,embryonic/larval dorsal branch,wing,head,third instar larva,trachea,embryonic/larval trachea,embryonic/larval transverse connective,taenidium,ectopic,mesothoracic tergum,dendritic arborizing neuron,second instar larval cuticle,macrochaeta & adult thoraxdpp.PH,adult thoracic sensillum,chaeta,head | pupal stage,wing | pupal stage,embryonic/larval dorsal branch | third instar larval stage,leg,basement membrane | pupal stage" FBgn0002732 E(spl)më±-BFM "Enhancer of split më±, Bearded family member" http://flybase.net/reports/FBgn0002732.html protein_coding_gene "0005515=protein binding, 0031625=ubiquitin protein ligase binding" "0007423=sensory organ development, 0001708=cell fate specification, 0007219=Notch signaling pathway" "CG8337, HLHmalpha, E(spl) malpha, DmelCG8337, E(spl) region transcript malpha, E(spl)ma, E(spl)malpha, E(spl)mmalpha, malpha" IPR029686=Enhancer of split malpha/m4 CG8337 16-Dec-15 2015_12 " embryonic stage | stage 8-17 , larval stage | third instar , embryonic stage | stage >7 , prepupal stage | stage P4 , prepupal stage | stage P4--pupal stage | stage P6 , embryonic stage | stage 6,7 , pupal stage | stage P6 " " ventral neurogenic region

, wing vein

, mesoderm

, sensillum campaniformium &&of wing

, morphogenetic furrow

, wing | restricted

, mesectoderm

, wing blade

, morphogenetic furrow | posterior to

, proneural cluster &&of dorsal mesothoracic disc

, proneural cluster &&of ventral thoracic disc

, wing cell

, wing margin

, dorsal mesothoracic disc | restricted

, proneural cluster

, eye disc

, ventral thoracic disc

" "visible,lethal,partially lethal - majority die,body color defective" "sensillum campaniformium,central nervous system,peripheral nervous system,adult sense organ,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,macrochaeta,ectopic,sensory mother cell,microchaeta,scutellar bristle,dorsocentral bristle,macrochaeta & scutumpnr-MD237,microchaeta & scutumpnr-MD237,trichogen cell,tormogen cell,thecogen cell,eo neuron,dorsal row & sensory mother cellap-md544,mesothoracic tergum" DRSC16994 E -0.285062749 -0.730975619 0.389453266 -2.278889564 1.049517815 0.346547471 FBgn0003118 pnt pointed http://flybase.net/reports/FBgn0003118.html "FBgn0004060, FBgn0005657, FBgn0010925, FBgn0011309" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0070491=repressing transcription factor binding, 0005515=protein binding" "0009997=negative regulation of cardioblast cell fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007362=terminal region determination, 0007455=eye-antennal disc morphogenesis, 0007429=secondary branching, open tracheal system, 0008284=positive regulation of cell proliferation, 0006909=phagocytosis, 0061320=pericardial nephrocyte differentiation, 0060439=trachea morphogenesis, 0007427=epithelial cell migration, open tracheal system, 0007424=open tracheal system development, 0007476=imaginal disc-derived wing morphogenesis, 0008340=determination of adult lifespan, 0060438=trachea development, 0007428=primary branching, open tracheal system, 0008293=torso signaling pathway, 0045467=R7 cell development, 0007426=tracheal outgrowth, open tracheal system, 0048190=wing disc dorsal/ventral pattern formation, 2001234=negative regulation of apoptotic signaling pathway, 0035225=determination of genital disc primordium, 0048747=muscle fiber development, 0007507=heart development, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0007422=peripheral nervous system development, 0007265=Ras protein signal transduction, 0050767=regulation of neurogenesis, 0030707=ovarian follicle cell development, 0006355=regulation of transcription, DNA-templated, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0045610=regulation of hemocyte differentiation, 0007464=R3/R4 cell fate commitment, 0007173=epidermal growth factor receptor signaling pathway" 0005634=nucleus "PNTP2, EK3-2, pnt-P1, no terminal cell clones-R, Pointed, Pnt2, ETS2, unnamed, pntP2, Pnt, pointedP2, 0998/12, Pointed-P2, PntP2, pnt-P2, pointed-RC, DMPOINT1A, Ets, pointed, D-Ets-2, 0608/07, pointed-P1, ets94F, Ets protein Pointed P2, ptd, pointed P2, Point2, pointed-P2, POINT, l(3)07825, E(E2F)3D, EC3-2, Ets at 58AB, pntegfr, PNT-P1, pnt, Pointed2, 0123/09, Ets94F, l(3)j1B7, PntP1, l(3)s118306, Ets2, PNTP1, Ets58AB, PointedP2, EY3-1, Pnt-P1, png, 3520, D-ets-2, Pointed-P1, CG17077" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain, IPR013761=Sterile alpha motif/pointed domain, IPR003118=Pointed domain" CG17077 16-Dec-15 2015_12 ENSDARG00000018308(ets2) "ENSXETG00000022781(ETS1),ENSXETG00000023724(ETS2)" "ENSMUSG00000032035(Ets1),ENSMUSG00000022895(Ets2)" "ENSG00000134954(ETS1),ENSG00000157557(ETS2)" " embryonic stage | stage 12-13 , embryonic stage | stage >=11 , embryonic stage | stage 12-14 , larval stage | third instar , embryonic stage | stage 6-12 , larval stage , embryonic stage , embryonic stage | early " " mesoderm

, embryonic/larval tracheal system

, interface glial cell

, ommatidium | restricted

, morphogenetic furrow | posterior to

, lateral ventral neurectoderm

, VUM neuron

, morphogenetic furrow

, maxillary segment

, imaginal disc primordium

, mandibular segment

, midline glial cell

, labial segment

, organism | 100% egg length

" larval stage " morphogenetic furrow | subset

, ommatidium | precursor

" "viable,fertile,cell polarity defective,planar polarity defective,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,dominant,neuroanatomy defective,somatic clone,mitotic cell cycle defective,homeotic,female sterile,female semi-sterile,size defective" "embryo,cardioblast,ectopic,ommatidium,photoreceptor,photoreceptor cell R7,eye photoreceptor cell,eye,interface glial cell,presumptive embryonic/larval central nervous system,midline glial cell,dorsal neurohemal organ,germarium,spectrosome | supernumeraryunspecified,embryonic/larval dorsal branch & terminal tracheal cell | somatic clone,terminal tracheal cell,embryonic/larval tracheal system,stomatogastric nervous system,macrochaeta,embryonic pericardial cell,lch5 neuron,midgut,abdominal 1 anterior commissure,abdominal 2 anterior commissure,abdominal 3 anterior commissure,abdominal 4 anterior commissure,abdominal 5 anterior commissure,abdominal 6 anterior commissure,abdominal 7 anterior commissure,abdominal 8 anterior commissure,abdominal 1 posterior commissure,abdominal 2 posterior commissure,abdominal 3 posterior commissure,abdominal 4 posterior commissure,abdominal 5 posterior commissure,abdominal 6 posterior commissure,abdominal 7 posterior commissure,abdominal 8 posterior commissure,wing,embryonic/first instar larval cuticle,ventral,adult salivary gland primordium,gastric caecum,midgut constriction 1,midgut chamber 3,visceral mesoderm,embryonic Malpighian tubule,embryonic ventral epidermis,dorsal appendage,maternal effect,somatic clone,dorsal air sac primordium,type II neuroblast,embryonic/larval glial cell,anterior fascicle sensory neuron,posterior fascicle sensory neuron,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,embryonic/larval ganglionic branch,lateral trunk anterior branch,lateral trunk posterior branch,embryonic/larval trachea,tracheal metamere,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,dorsal branch primordium,commissure,ventral nerve cord,eye disc,mitotic cell cycle | somatic clone,Bolwig nerve,presumptive embryonic/larval tracheal system,Malpighian tubule,genital disc primordium,mesoderm,embryonic/larval pericardial cell,A1-7 dorsal acute muscle 1,A1-7 ventral acute muscle 2,precursor,denticle belt,exit glial cell,glial cell,trachea,tracheal fusion cell,supernumerary,ommatidial precursor cluster,embryonic/larval dorsal trunk,bract,abdominal neuromere,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,cephalopharyngeal skeleton,anterior commissure,ganglionic branch primordium,photoreceptor cell R1,photoreceptor cell R6,wing disc,central nervous system,melanotic mass,hemocyte,antenna,morphogenetic furrow,submarginal cell,wing vein L4,pigment cell,photoreceptor cell R8,rhabdomere R8,muscle founder cell,dorsal oblique muscle,pericardial cell,dorsal acute muscle,cone cell,embryonic/larval brain,ventral nerve cord | larval stage,secondary neuroblast,ectopic | larval stage" DRSC23204 K 1.09824732 2.796468736 FBgn0001645 l(1)dn25 lethal (1) discs normal 25 http://flybase.net/reports/FBgn0001645.html gene "l(1)d norm-25, l(1)d.norm.-25" 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014058 Su(tor)2-48 Su(tor)2-48 http://flybase.net/reports/FBgn0014058.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0021875 Zfrp8 Zinc finger protein RP-8 http://flybase.net/reports/FBgn0021875.html FBgn0034981 protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" "0035162=embryonic hemopoiesis, 0048103=somatic stem cell division, 0008283=cell proliferation, 0048477=oogenesis" "0005634=nucleus, 0005737=cytoplasm" "CG3260, zfrp8, programmed cell death 2, PDCD2, zinc finger RP8, 137/5, l(2)k13705" "IPR002893=Zinc finger, MYND-type, IPR007320=Programmed cell death protein 2, C-terminal" CG3260 16-Dec-15 2015_12 ENSDARG00000007892(pdcd2) YOL022C(TSR4) WBGene00011116(pdcd-2) ENSXETG00000008555(PDCD2) ENSMUSG00000014771(Pdcd2) ENSG00000071994(PDCD2) "lethal,recessive,developmental rate defective,hyperplasia,lethal - all die before end of larval stage,some die during larval stage,melanotic necrosis,viable" "female germline stem cell,ovariole,spectrosomenos.UTR.THsimVP16,follicle stem cell,somatic clone,female germline cyst,germline clone,spectrosome | germline clone,embryonic/larval lymph gland,embryonic/larval hemocyte,supernumerary,lamellocyte,plasmatocyte,crystal cell,melanotic mass" DRSC04352 K 0.781602195 0.115796747 -0.053186287 0.613806657 2.21922239 1.274304349 FBgn0010452 trn tartan http://flybase.net/reports/FBgn0010452.html FBgn0025231 protein_coding_gene "0007436=larval salivary gland morphogenesis, 0016477=cell migration, 0007476=imaginal disc-derived wing morphogenesis, 0007424=open tracheal system development, 0008045=motor neuron axon guidance, 0035147=branch fusion, open tracheal system, 0007155=cell adhesion" 0005886=plasma membrane "anon-fast-evolving-2B1, CT31487, 0024/05, TARTAN, unnamed, anon-EST:fe2B1, 0641/17, Tartan, CG11280" "IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat, IPR000483=Cysteine-rich flanking region, C-terminal, IPR003591=Leucine-rich repeat, typical subtype" CG11280 16-Dec-15 2015_12 "ENSDARG00000062400(LOC558051),ENSDARG00000059430,ENSDARG00000060115(lrrn1)" WBGene00022129(Y71F9B.8) "ENSXETG00000005147(LRRN1),ENSXETG00000024194()" "ENSMUSG00000036295(Lrrn3),ENSMUSG00000026443(Lrrn2),ENSMUSG00000034648(Lrrn1)" "ENSG00000173114(LRRN3),ENSG00000175928(LRRN1),ENSG00000170382(LRRN2)" " embryonic stage | stage >=8 , embryonic stage | stage 15-16 , larval stage | third instar , embryonic stage | stage 15,16 , embryonic stage | stage 16,17 , larval stage&&pupal stage , embryonic stage | stage 5 , embryonic stage -- adult stage " " sense organ | precursor

, embryonic/larval hindgut

, ventral thoracic disc

, stomodeum

, morphogenetic furrow | anterior

, proctodeum

, central nervous system

, larval outer optic anlage

,

pair rule , embryonic peripheral nervous system | restricted

, eye-antennal disc

, larval inner optic anlage

, dorsal mesothoracic disc

, peripheral nervous system

, morphogenetic furrow | posterior to

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during immature adult stage,somatic clone,viable" "lch5 neuron,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,A1-7 lateral transverse muscle 4,A1-7 dorsal transverse muscle 1,embryonic/larval salivary gland,presumptive embryonic/larval peripheral nervous system,embryonic/larval somatic muscle,antennal lobe projection neuron lPN,somatic clone,dendrite | somatic clone,lateral trunk primordium,pretarsus,dorsal trunk primordium,intersegmental nerve,motor neuron,wing disc,ventral compartment,ventral thoracic disc,motor neuron | larval stage" FBgn0000440 dft deformed tergites http://flybase.net/reports/FBgn0000440.html gene 16-Dec-15 2015_12 "visible,male fertile,poor,partially lethal - majority live,viable,male,male sterile" "eye,wing,macrochaeta,posterior scutellar bristle,dorsocentral bristle,adult abdomen,adult abdomen & microchaeta" FBgn0025761 l(3)93DFa lethal (3) 93DFa http://flybase.net/reports/FBgn0025761.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0035026 Fcp1 TFIIF-interacting CTD phosphatase http://flybase.net/reports/FBgn0035026.html protein_coding_gene 0008420=CTD phosphatase activity "0022008=neurogenesis, 0006470=protein dephosphorylation" "0005700=polytene chromosome, 0005634=nucleus" "fcp1, CG12252, TFIIF-interacting CTD phosphatase, 21483550, RNApolymerase II carboxyl-terminal domain phosphatase, DmFcp1, Dmfcp1" "IPR023214=HAD-like domain, IPR004274=FCP1 homology domain, IPR011947=FCP1-like phosphatase, phosphatase domain, IPR001357=BRCT domain" CG12252 16-Dec-15 2015_12 ENSDARG00000017522(ctdp1) YMR277W(FCP1) WBGene00009479(fcp-1) ENSXETG00000000856(ctdp1) ENSMUSG00000033323(Ctdp1) ENSG00000060069(CTDP1) "lethal - all die during third instar larval stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,visible,increased cell death,wild-type,lethal - all die before end of prepupal stage,some die during third instar larval stage,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval neuroblast,ganglion mother cell,wing,eye,imaginal disc,polytene chromosome puff,polytene chromosome puffhs.PB,egg,maternal effect" FBgn0023130 a6 a6 http://flybase.net/reports/FBgn0023130.html protein_coding_gene 0005549=odorant binding 0001700=embryonic development via the syncytial blastoderm "EG:9D2.3, CG3771" CG3771 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0003240 rey rough eye http://flybase.net/reports/FBgn0003240.html gene "re, rougheye-like" 16-Dec-15 2015_12 "female sterile,visible,recessive,female fertile,poor,viable,female" "eye,adult thorax" FBgn0000926 fs(1)se female sterile (1) small eggs http://flybase.net/reports/FBgn0000926.html gene fs(1)107 16-Dec-15 2015_12 "female sterile,recessive" egg chamber FBgn0038454 CG10324 http://flybase.net/reports/FBgn0038454.html protein_coding_gene "0003676=nucleic acid binding, 0005515=protein binding" 0022008=neurogenesis 0005654=nucleoplasm "IPR026822=Spp2/MOS2, G-patch domain, IPR000467=G-patch domain" CG10324 16-Dec-15 2015_12 ENSDARG00000029612(t54l) WBGene00011237(R11A8.2) ENSXETG00000007727(gpkow) ENSMUSG00000031148(Gpkow) ENSG00000068394(GPKOW) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0013764 Chi Chip http://flybase.net/reports/FBgn0013764.html "FBgn0020536, FBgn0024338" protein_coding_gene "0001085=RNA polymerase II transcription factor binding, 0008134=transcription factor binding, 0003712=transcription cofactor activity, 0005515=protein binding, 0030274=LIM domain binding" "0007350=blastoderm segmentation, 0010468=regulation of gene expression, 0007399=nervous system development, 0007563=regulation of eclosion, 0022416=chaeta development, 0007411=axon guidance, 0007476=imaginal disc-derived wing morphogenesis, 0045893=positive regulation of transcription, DNA-templated, 0070983=dendrite guidance, 0006351=transcription, DNA-templated, 0006909=phagocytosis, 0048749=compound eye development, 0008407=chaeta morphogenesis" 0005634=nucleus "l(2)k04405, dLdb, LDB, CG3924, dLDB/Chip, l(2)04405, Ldb, Chip, chip, CHIP" "IPR002691=LIM-domain binding protein, IPR029005=LIM-domain binding protein/SEUSS" CG3924 16-Dec-15 2015_12 ENSDARG00000010137(ldb1a) WBGene00002261(ldb-1) ENSXETG00000001714(ldb1) "ENSMUSG00000039706(Ldb2),ENSMUSG00000025223(Ldb1)" "ENSG00000169744(LDB2),ENSG00000198728(LDB1)" embryonic stage -- adult stage " larval stage , embryonic stage && larval stage " " embryonic/larval fat body

,

, embryonic/larval salivary gland

, imaginal disc

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,visible,somatic clone,size defective,wild-type,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,non-rescuable maternal effect,neuroanatomy defective,eclosion defective,heat sensitive,partially lethal - majority die,some die during pupal stage" "eye,ectopic,somatic clone,head capsule,vibrissae,rostral membrane,ocellus,antenna,maxillary palpus,eye-antennal disc,somatic clone - Minute background,photoreceptor cell,somatic clone | third instar larval stage,thorax,wing,embryo,dorsocentral bristle,posterior postalar bristle,scutellar bristle,supernumerary,adult thorax,wing margin,dorsal compartment,wing disc,leg,tarsal segment 4,unguis,interneuron,embryonic/larval neuron,germline clone,embryonic/first instar larval cuticle,adult antennal lobe projection neuron,antennal lobe projection neuron adPN,antennal lobe glomerulus VA1,antennal lobe glomerulus D,antennal lobe glomerulus DL1,antennal lobe glomerulus VM7,antennal lobe glomerulus VA3,antennal lobe glomerulus VM2,antennal lobe glomerulus DM6,antennal lobe glomerulus DA1,antennal lobe glomerulus VA5,antennal lobe glomerulus DM5,antennal lobe glomerulus DM2,antennal lobe glomerulus DM1,subesophageal ganglion,pretarsus,antennal lobe glomerulus VA1v,dorsal/ventral compartment boundary,distal,heat sensitive,alula,mesothoracic tergum,anterior dorsocentral bristle,posterior dorsocentral bristle,chaeta,trichogen cell" DRSC04602 K -0.519128937 -0.283141601 0.672925901 0.111594062 1.616826259 0.749218418 FBgn0024798 Dipr Distal into proximal http://flybase.net/reports/FBgn0024798.html gene 16-Dec-15 2015_12 "wild-type,viable,visible,dominant,homeotic,body color defective" "wing,distal,dorsal triple row,medial triple row,ventral triple row,trichome of the posterior wing margin,wing hair,wing vein,proximal,capitellum,tarsal segment 2,tarsal segment 3,tarsal segment 4,prothoracic tarsal segment 2,sex comb,ectopic,basal cylinder,pseudotrachea,metatarsus" FBgn0027233 l(1)G0286 lethal (1) G0286 http://flybase.net/reports/FBgn0027233.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0010602 lwr lesswright http://flybase.net/reports/FBgn0010602.html "FBgn0010523, FBgn0015755, FBgn0022761" protein_coding_gene "0008134=transcription factor binding, 0019789=SUMO transferase activity, 0031072=heat shock protein binding, 0061665=SUMO ligase activity, 0033134=ubiquitin activating enzyme binding" "0007391=dorsal closure, 0007143=female meiotic division, 0035172=hemocyte proliferation, 0016321=female meiosis chromosome segregation, 0035204=negative regulation of lamellocyte differentiation, 0008354=germ cell migration, 0035207=negative regulation of hemocyte proliferation, 0006606=protein import into nucleus, 0016925=protein sumoylation, 0030721=spectrosome organization, 0006464=cellular protein modification process, 0007095=mitotic G2 DNA damage checkpoint, 0045751=negative regulation of Toll signaling pathway, 0006959=humoral immune response, 0071560=cellular response to transforming growth factor beta stimulus, 0007352=zygotic specification of dorsal/ventral axis" "0005634=nucleus, 0000780=condensed nuclear chromosome, centromeric region, 0000940=condensed chromosome outer kinetochore" "Lesswright, Lwr, semi, i56, Ubiquitin conjugating enzyme 9, ubiquitin-conjugating enzyme 9, Ubc 9, Ubc-9, i105, DmUbc9, ubc9, l(2)02858, dUBC9, dUbc9, l(2)05486, CG3018, l(2)05487, DUbc9, semushi, Iwr, unnamed, hunchback-like, FBgn0010602, l(2)01519, Ubc9, UBC9, UbcD9, Dmubc9, hbl, dip4" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2, IPR027230=SUMO-conjugating enzyme Ubc9, IPR023313=Ubiquitin-conjugating enzyme, active site" CG3018 16-Dec-15 2015_12 "ENSDARG00000052649(ube2i2),ENSDARG00000007438" YDL064W(UBC9) WBGene00006706(ubc-9) ENSXETG00000004027(ube2i) ENSMUSG00000015120(Ube2i) ENSG00000103275(UBE2I) " embryonic stage , embryonic stage | syncytial blastoderm "

anterior " embryonic stage , adult stage | female " organism

"immune response defective,tumorigenic,lethal,recessive,rescuable maternal effect,maternal effect,neuroanatomy defective,somatic clone,melanotic mass phenotype,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,partially,enhancer of variegation,partially lethal - majority die,visible,wild-type,mitotic cell cycle defective,germline clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval fat body,embryonic/larval hemocoel,embryonic epidermis,embryonic head,embryonic thoracic segment,embryonic abdominal segment,leg,adult head,wing,eye,neuroblast,somatic clone,embryonic/larval hemocyte,supernumerary,lamellocyte,plasmatocyte,hemocyte,crystal cell,melanotic mass,hemocyte & nucleus | supernumerary,embryonic/first instar larval cuticle,adult antennal lobe projection neuron DL1 adPN,antennal lobe glomerulus DL1,dendrite | somatic clone,eye disc" DRSC00828 E 0.9479729 -0.705051992 1.685084091 -0.070291204 -0.529128007 0.962574336 FBgn0005614 trpl transient receptor potential-like http://flybase.net/reports/FBgn0005614.html FBgn0042195 protein_coding_gene "0015279=store-operated calcium channel activity, 0005262=calcium channel activity, 0046982=protein heterodimerization activity, 0005261=cation channel activity, 0010461=light-activated ion channel activity, 0005515=protein binding, 0005516=calmodulin binding, 0042802=identical protein binding" "0009416=response to light stimulus, 0006816=calcium ion transport, 0070588=calcium ion transmembrane transport, 0007603=phototransduction, visible light, 0007589=body fluid secretion, 0019722=calcium-mediated signaling, 0006812=cation transport, 0007605=sensory perception of sound, 0071454=cellular response to anoxia" "0034703=cation channel complex, 0016028=rhabdomere, 0016027=inaD signaling complex, 0035997=rhabdomere microvillus membrane, 0005886=plasma membrane, 0030425=dendrite" "CG1694, dTrpL, TrpL, trp-l, TRPL, TRP-Like, Transient Receptor Potential-Like, DmTRPL, trp-like, transient receptor potential-like, TRP-like, trpL, Trpl, CG18345, dTRPL" "IPR013555=Transient receptor ion channel domain, IPR005821=Ion transport domain, IPR004729=Transient receptor potential channel, IPR002153=Transient receptor potential channel, canonical, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG18345 16-Dec-15 2015_12 "ENSDARG00000062183(LOC566436),ENSDARG00000070504,ENSDARG00000070507(LOC555897),ENSDARG00000060837" WBGene00006615(trp-2) "ENSXETG00000001811(TRPC4),ENSXETG00000012403(TRPC5)" "ENSMUSG00000027748(Trpc4),ENSMUSG00000041710(Trpc5)" "ENSG00000133107(TRPC4),ENSG00000072315(TRPC5)" adult stage photoreceptor cell

adult stage rhabdomere

"neurophysiology defective,visual behavior defective,chemosensitive behavior defective,taste perception defective,thermotaxis behavior defective,wild-type,auditory perception defective,viable" "photoreceptor cell,photoreceptor,photoreceptor cell & axon,S-type sensilla S6,eye photoreceptor cell,L-type sensilla L2,Malpighian tubule" DRSC06729 K 0.633569824 0.210869085 0.16445543 1.097994 1.539794396 -0.998261165 FBgn0025286 RpL31 Ribosomal protein L31 http://flybase.net/reports/FBgn0025286.html "FBgn0033430, FBgn0062997" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "Rp L31, CG1821, BcDNA:RE59131, M(2)45F, anon-EST:Posey68" "IPR020052=Ribosomal protein L31e, conserved site, IPR000054=Ribosomal protein L31e, IPR023621=Ribosomal protein L31e domain" CG1821 16-Dec-15 2015_12 ENSDARG00000053365(zgc:136896) "YLR406C(RPL31B),YDL075W(RPL31A)" WBGene00004445(rpl-31) ENSXETG00000024667(Q6DEN9_XENTR) "ENSMUSG00000073702(Rpl31),ENSMUSG00000067870(Gm8759),ENSMUSG00000059999(Gm10072),ENSMUSG00000072255(Gm16382),ENSMUSG00000051723,ENSMUSG00000058607(Gm6635),ENSMUSG00000066389(Rpl31-ps1),ENSMUSG00000059827(Gm5670)" ENSG00000071082(RPL31) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC06716 IEK -1.722202266 -1.725588729 -1.417356415 -3.706249868 -0.831050641 2.684574962 FBgn0002791 mr morula http://flybase.net/reports/FBgn0002791.html FBgn0034947 protein_coding_gene "0031625=ubiquitin protein ligase binding, 0090302=APC-Cdc20 complex activity" "0045886=negative regulation of synaptic growth at neuromuscular junction, 0050804=regulation of synaptic transmission, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0051726=regulation of cell cycle" "0000151=ubiquitin ligase complex, 0005680=anaphase-promoting complex" "dAPC2, APC2/mr, APC2, MR, Morula, CG3060, Apc2" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR016158=Cullin homology, IPR001373=Cullin, N-terminal, IPR014786=Anaphase-promoting complex subunit 2, C-terminal" CG3060 16-Dec-15 2015_12 ENSDARG00000005832(anapc2) YLR127C(APC2) WBGene00000143(apc-2) ENSXETG00000022932(ANAPC2) ENSMUSG00000026965(Anapc2) ENSG00000176248(ANAPC2) "viable,fertile,lethal,partially,neurophysiology defective,neuroanatomy defective,recessive,mitotic cell cycle defective,somatic clone,germline clone,visible,sterile,female sterile" "embryonic/larval neuromuscular junction,NMJ bouton,supernumerary,nurse cell & nuclear chromosome,nurse cell & spindle,eye,somatic clone,macrochaeta,mitotic cell cycle | larval stage | somatic clone,mitotic cell cycle | germline clone,spindle | germline clone,hindgut imaginal ring,embryonic/larval salivary gland,ring gland,nurse cell,spindle | maternal effect,nuclear chromosome | maternal effect,nurse cell & nucleus,follicle cell,nurse cell ring canal,egg,embryo,mitotic cell cycle | embryonic stage,polar body nucleus,spindle | embryonic stage,tergite,trichogen cell,mesothoracic tergum" DRSC04332 K -0.379924778 -0.188079924 1.327161857 -0.056307541 0.277123298 -1.897025145 FBgn0036516 CG7656 http://flybase.net/reports/FBgn0036516.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0022008=neurogenesis, 0000209=protein polyubiquitination" "IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2, IPR023313=Ubiquitin-conjugating enzyme, active site" CG7656 16-Dec-15 2015_12 "ENSDARG00000012627(cdc34b),ENSDARG00000069708(cdc34a),ENSDARG00000058740(ube2r2)" YDR054C(CDC34) WBGene00006702(ubc-3) "ENSXETG00000002154(UBE2R2),ENSXETG00000006555(cdc34)" "ENSMUSG00000036241(Ube2r2),ENSMUSG00000020307(Cdc34),ENSMUSG00000020870" "ENSG00000107341(UBE2R2),ENSG00000099804(CDC34)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,chaeta,supernumerary,mesothoracic tergum" DRSC10900 K 0.469023476 0.3818229 0.319878193 0.088338656 1.51916032 0.468978563 FBgn0000357 Cp18 Chorion protein 18 http://flybase.net/reports/FBgn0000357.html FBgn0004941 protein_coding_gene 0005213=structural constituent of chorion "0007275=multicellular organismal development, 0007306=eggshell chorion assembly" 0042600=chorion "s18-1, Dms18, CP18, unnamed, Chorion Protein 18, E5, CG6517, s18, S18, Shell-18, s-18, ACE3, cp18, S-18, chorion protein 18" IPR005649=Chorion 2 CG6517 16-Dec-15 2015_12 " oogenesis stage | stage S11-14 , adult stage && oogenesis stage | stage S13-14 , adult stage | female " follicle cell

" adult stage | female , adult stage && oogenesis stage | stage S13-14 , embryonic stage , oogenesis stage | stage S13-14 " " ovary

{ v fs(1)A1059K1 } , follicle cell

, ovary

{ 0 swa6 } , vitelline membrane

, ovary

, ovary

{ v mus101K451 } " viable FBgn0020307 dve defective proventriculus http://flybase.net/reports/FBgn0020307.html "FBgn0010496, FBgn0041142" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003680=AT DNA binding" "0016348=imaginal disc-derived leg joint morphogenesis, 0015677=copper ion import, 0007476=imaginal disc-derived wing morphogenesis, 0048608=reproductive structure development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0007494=midgut development" "0005829=cytosol, 0005634=nucleus" "compass, l(2)01738, CG5799, DVE, Defective proventriculus, Dve-s, Defective Proventriculus, Dve, dep, unnamed, SATB1" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like" CG5799 16-Dec-15 2015_12 WBGene00022861(dve-1) "ENSMUSG00000023927(Satb1),ENSMUSG00000038331(Satb2)" "ENSG00000182568(SATB1),ENSG00000119042(SATB2)" " embryonic stage | stage >=9 , embryonic stage | stage 13 , embryonic stage | stage 12 , embryonic stage | stage 16 , embryonic stage | stage 13-17 , embryonic stage | 0-18 hr , embryonic stage | stage 9 " " anterior midgut proper primordium | restricted

, ventral nerve cord | restricted

, posterior midgut proper primordium | anterior

, embryonic/larval pharynx | vicinity of

, proventriculus outer layer

, embryonic/larval midgut | restricted

, embryonic brain | restricted

, mesectoderm | restricted

" " embryonic stage | stage 16 , larval stage | third instar , embryonic stage | stage >=11 , embryonic stage | stage >=13 , embryonic stage | stage 10 " " proventriculus outer layer

, dorsal mesothoracic disc | restricted

, anterior midgut proper primordium | restricted

, posterior embryonic/larval midgut | restricted

, specialised larval midgut cell | precursor

, mid embryonic/larval midgut | restricted

, stomodeum

" "mating behavior defective,female,visible,partially lethal - majority die,partially lethal,small body,recessive,lethal,viable,fertile,somatic clone,lethal - all die before end of larval stage,some die during larval stage" "male accessory gland,male accessory gland main cell,cuprophilic cell,wing,midgut,proventriculus,male accessory gland secondary cell,larva,embryonic/larval midgut,somatic clone,wing margin bristle,ectopic,proximal,wing vein L2,wing vein L5,distal,wing disc,embryonic/larval proventriculus,proventriculus outer layer,proventriculus inner layer,joint,tarsal segment,dorsal | pharate adult stage,eye disc,male limited,heat sensitive" FBgn0004132 boca boca http://flybase.net/reports/FBgn0004132.html "FBgn0033193, FBgn0050498" protein_coding_gene "0016055=Wnt signaling pathway, 0006888=ER to Golgi vesicle-mediated transport, 0048728=proboscis development, 0048477=oogenesis, 0006612=protein targeting to membrane, 0032799=low-density lipoprotein receptor particle metabolic process" "0005737=cytoplasm, 0012505=endomembrane system, 0045177=apical part of cell, 0005788=endoplasmic reticulum lumen, 0005783=endoplasmic reticulum" "l(2)43Ea, Boca, CG30498, CG1364, lethal(2)43Ea, dmBoca" IPR019330=Mesoderm development candidate 2 CG30498 16-Dec-15 2015_12 ENSDARG00000063030 WBGene00017293(bmy-1) ENSXETG00000012980(MESDC2) ENSMUSG00000038503(Mesdc2) ENSG00000117899(MESDC2) "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage,viable" "wing margin bristle,cell autonomous,somatic clone,cell non-autonomous,ectopic,dorsocentral bristle,eye,adult head,dorsal,wing disc,ventral thoracic disc,distal,yolk,germline clone,proboscis" FBgn0036577 CG13073 http://flybase.net/reports/FBgn0036577.html protein_coding_gene 0022008=neurogenesis CG13073 16-Dec-15 2015_12 "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0060611 l(3)S090303 lethal (3) S090303 http://flybase.net/reports/FBgn0060611.html gene 0903/03 16-Dec-15 2015_12 "lethal,recessive" FBgn0062625 Mod(var)1116 Mod(var)1116 http://flybase.net/reports/FBgn0062625.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1116 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,viable" FBgn0019662 qm quemao http://flybase.net/reports/FBgn0019662.html protein_coding_gene "0004161=dimethylallyltranstransferase activity, 0004337=geranyltranstransferase activity, 0004311=farnesyltranstransferase activity" "0008354=germ cell migration, 0022008=neurogenesis, 0008299=isoprenoid biosynthetic process, 0048477=oogenesis, 0035050=embryonic heart tube development" "geranylgeranyl pyrophosphate synthase, CG8593, que mao, GGPPS/qm, GGPPS, bro2" "IPR017446=Polyprenyl synthetase-related, IPR008949=Isoprenoid synthase domain, IPR000092=Polyprenyl synthetase" CG8593 16-Dec-15 2015_12 ENSDARG00000023627 YPL069C(BTS1) ENSXETG00000013068(TEgg066f14.1) ENSMUSG00000021302(Ggps1) ENSG00000152904(GGPS1) embryonic stage -- adult stage "wild-type,viable,fertile,visible,recessive,female fertile,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,germline clone,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,partially lethal - majority die" "nurse cell ring canal,germline clone,egg chamber,macrochaeta,adult thorax & macrochaeta,sternopleural bristle,head bristle,sex comb,adult abdomen,adult cuticle & abdomen,macrochaeta & adult abdomen,pole cell,larva,cephalopharyngeal skeleton,embryonic pericardial cell,cardioblast,pole cell & embryonic nervous system,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0037838 CG4089 http://flybase.net/reports/FBgn0037838.html protein_coding_gene 0006464=cellular protein modification process IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase CG4089 16-Dec-15 2015_12 WBGene00010630(ttll-15) viable FBgn0038869 CG3353 http://flybase.net/reports/FBgn0038869.html protein_coding_gene "IPR001214=SET domain, IPR002893=Zinc finger, MYND-type, IPR016024=Armadillo-type fold" CG3353 16-Dec-15 2015_12 ENSDARG00000071669(smyd5) ENSXETG00000011764(smyd5) ENSMUSG00000033706(Smyd5) ENSG00000135632(SMYD5) "neuroanatomy defective,viable" "Kenyon cell,adult mushroom body" DRSC15483 E 0.322704837 0.241112724 2.368212694 1.115961955 -0.985748929 -0.633077595 FBgn0052685 ZAP3 http://flybase.net/reports/FBgn0052685.html "FBgn0030175, FBgn0030176, FBgn0040939" protein_coding_gene 0008157=protein phosphatase 1 binding 0048812=neuron projection morphogenesis 0005634=nucleus "CG12647, CG32685, CG2971, CG12646" "IPR026314=YLP motif-containing protein 1, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG32685 16-Dec-15 2015_12 ENSDARG00000043680(si:ch211-59d15.5) ENSXETG00000013269(YLPM1) ENSMUSG00000021244(Ylpm1) ENSG00000119596(YLPM1) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC18249 I -0.030640317 1.643603085 0.449084824 0.451095422 -0.436420371 -0.495052033 FBgn0038168 omd oocyte maintenance defects http://flybase.net/reports/FBgn0038168.html protein_coding_gene "0034472=snRNA 3'-end processing, 0022008=neurogenesis" 0032039=integrator complex "CG9591, IntS5, Integrator 5, Omd" "IPR029445=Integrator complex subunit 5, N-terminal, IPR029444=Integrator complex subunit 5, C-terminal" CG9591 16-Dec-15 2015_12 ENSXETG00000005479(INTS5) ENSMUSG00000071652(Ints5) ENSG00000185085(INTS5) "lethal,female fertile,poor,viable,fertile,neuroanatomy defective,partially lethal - majority die,visible" "wing,wing vein,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC16507 IK -0.914094748 -1.81691891 0.212004658 -0.764237089 -1.720575785 -0.004080548 FBgn0035574 RhoGEF64C Rho guanine nucleotide exchange factor at 64C http://flybase.net/reports/FBgn0035574.html "FBgn0035573, FBgn0052239, FBgn0062671" protein_coding_gene "0005089=Rho guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity" "0007480=imaginal disc-derived leg morphogenesis, 0002121=inter-male aggressive behavior, 0007411=axon guidance, 0035025=positive regulation of Rho protein signal transduction, 0035277=spiracle morphogenesis, open tracheal system" 0045179=apical cortex "CG32239, Guanine nucleotide exchange factor 64C, CG13710, EP(3)3035, guanine nucleotide exchange factor, Guanine nucleotide exchange factor, GEF(64C), EP3035, GEF, Gef64C, RhoGEF, Rho guanine nucleotide exchange factor, Guanine nucleotide exchange factor GEF64C, GEF64C, CG13709, RhoGef64C, RhoGEF64C" "IPR000219=Dbl homology (DH) domain, IPR001849=Pleckstrin homology domain" CG32239 16-Dec-15 2015_12 embryonic stage " embryonic central nervous system

,

ubiquitous " "viable,neuroanatomy defective,behavior defective,recessive,long lived,starvation stress response defective,temperature response defective,gravitaxis defective,male limited,fertile,visible,partially lethal - majority die,some die during pupal stage" "ventral nerve cord commissure,longitudinal connective,commissure,eye,actin filament & embryonic/larval tracheal systembtl.PS,mesothoracic tergum" DRSC08319 K -0.147860124 -0.752479413 -0.605524131 0.337786363 0.540863757 2.51310002 FBgn0261268 Cul3 Cullin 3 http://flybase.net/reports/FBgn0261268.html "FBgn0001980, FBgn0027882, FBgn0051829" protein_coding_gene "0031625=ubiquitin protein ligase binding, 0004842=ubiquitin-protein transferase activity" "0007476=imaginal disc-derived wing morphogenesis, 0006511=ubiquitin-dependent protein catabolic process, 0007291=sperm individualization, 0048813=dendrite morphogenesis, 0030162=regulation of proteolysis, 0045187=regulation of circadian sleep/wake cycle, sleep, 0001745=compound eye morphogenesis, 0007409=axonogenesis, 0007283=spermatogenesis, 0030431=sleep, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0016567=protein ubiquitination, 0007423=sensory organ development, 0045475=locomotor rhythm" "0000152=nuclear ubiquitin ligase complex, 0031463=Cul3-RING ubiquitin ligase complex, 0005737=cytoplasm, 0035324=female germline ring canal" "gft/dCul-3, l(2)35Cd, DMcul-3, Cul3, CG31829, dCul-3, cul3, gft, CUL3, dCul3, l(2)06430, cullin 3, CUL-3, l(2)br34, medusa, CG42616, cul-3, cullin3, Cullin3, mds, Cullin, br34, Cul-3, cullin-3, CG11861, BG:DS07851.2, Cullin-3, Cullin 3, guftagu, l35Cd" "IPR016157=Cullin, conserved site, IPR016159=Cullin repeat-like-containing domain, IPR001373=Cullin, N-terminal, IPR016158=Cullin homology, IPR019559=Cullin protein, neddylation domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG42616 16-Dec-15 2015_12 "some die during embryonic stage,recessive,locomotor rhythm defective,male fertile,male sterile,partially,lethal - all die before end of embryonic stage,lethal - all die before end of larval stage,some die during larval stage,lethal,germline clone,maternal effect,visible,somatic clone,neuroanatomy defective,sleep defective,partially lethal - majority die,viable,RU486 conditional" "dorsal appendage,germline clone,maternal effect,egg,wing,somatic clone,wing vein,wing vein L3,sensillum campaniformium of dorsal radius,ectopic,sensillum campaniformium,wing hair,external sensory organ,microchaeta,macrochaeta,trichogen cell,sensory mother cell,cell autonomous,wing disc,neuron & mushroom body,spermatid,nurse cell ring canal,filamentous actin,neuron & beta-lobe,neuron & gamma-lobe,neuron & alpha-lobe,wing vein L4,anterior crossvein,mesothoracic tergum & macrochaeta-4512,scutellum & macrochaeta-4512,sensillum campaniformium & wing-4512,wing margin bristle" FBgn0003973 ven venation http://flybase.net/reports/FBgn0003973.html gene 16-Dec-15 2015_12 "small body,sterile" "wing vein,wing vein L3,crossvein,eye,macrochaeta" FBgn0259669 B0942 http://flybase.net/reports/FBgn0259669.html gene 16-Dec-15 2015_12 visible "tarsal segment,unguis,arista,anterior crossvein" FBgn0035458 ppk27 pickpocket 27 http://flybase.net/reports/FBgn0035458.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "pickpocket 27, ppk27, CG10858" "IPR001873=Na+ channel, amiloride-sensitive" CG10858 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage,viable" FBgn0004643 Zw10 Zeste-white 10 http://flybase.net/reports/FBgn0004643.html "FBgn0000016, FBgn0002765, FBgn0029627, FBtr0070441, FBpp0070425" protein_coding_gene 0005515=protein binding "0007107=membrane addition at site of cytokinesis, 0048193=Golgi vesicle transport, 0007094=mitotic spindle assembly checkpoint, 0007112=male meiosis cytokinesis, 0036090=cleavage furrow ingression, 0007059=chromosome segregation, 0007060=male meiosis chromosome segregation, 0007030=Golgi organization, 0000278=mitotic cell cycle, 0022008=neurogenesis, 0000070=mitotic sister chromatid segregation" "0036063=acroblast, 0005783=endoplasmic reticulum, 0051233=spindle midzone, 0000776=kinetochore, 0005737=cytoplasm, 0005634=nucleus, 0005795=Golgi stack, 1990423=RZZ complex, 0005828=kinetochore microtubule, 0000940=condensed chromosome outer kinetochore, 0070939=Dsl1p complex" "l(1)6-99, CG9900, abe, Mit(1)15, mit(1)15, abnormal-eye, Zw10, l(1)3Af, Zeste-White 10, Dsl1, zw-10, EG:BACR7C10.3, l(1)zw10, ZW10, dZW10, mitotic 15, ZW-10, mit(l)15, zw10" "IPR009361=RZZ complex, subunit Zw10" CG9900 16-Dec-15 2015_12 ENSDARG00000018738(zw10) WBGene00017643(czw-1) ENSXETG00000022977(ZW10) ENSMUSG00000032264(Zw10) ENSG00000086827(ZW10) " embryonic stage--pupal stage , adult stage | female " " larval stage | third instar , embryonic stage | syncytial blastoderm , spermatogenesis && adult stage , embryonic stage | 0-16 hr " " onion stage spermatid

, spermatocyte

" "cytokinesis defective,meiotic cell cycle defective,lethal,recessive,male sterile,partially lethal - majority die,polyphasic,mitotic cell cycle defective,female sterile,visible,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,viable,male fertile,wild-type,heat sensitive,neuroanatomy defective" "scutellar bristle,anterior vertical bristle,posterior vertical bristle,spermatid,Nebenkern,nuclear chromosome | embryonic stage | germline clone,eye,wing,wing vein,dorsocentral bristle,ocellar bristle,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,spermatozoon,testis,onion stage spermatid,egg,germline clone,maternal effect,female reproductive system,macrochaeta & thorax,macrochaeta & head,nucleus | embryonic stage | germline clone,Golgi stack,contractile ring,spindle,cleavage furrow,acroblast,neuroblast,wing vein L4,secondary spermatocyte,spermatocyte,meiotic cell cycle,mitotic anaphase,nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0010382 CycE Cyclin E http://flybase.net/reports/FBgn0010382.html "FBgn0001984, FBgn0010318, FBgn0015389, FBgn0022237" protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0005515=protein binding" "0006275=regulation of DNA replication, 0008360=regulation of cell shape, 0007277=pole cell development, 0048665=neuron fate specification, 0045035=sensory organ precursor cell division, 0042127=regulation of cell proliferation, 0060564=negative regulation of APC-Cdc20 complex activity, 0006974=cellular response to DNA damage stimulus, 0007400=neuroblast fate determination, 0000082=G1/S transition of mitotic cell cycle, 0035736=cell proliferation involved in compound eye morphogenesis, 0035019=somatic stem cell maintenance, 0044719=regulation of imaginal disc-derived wing size, 0001932=regulation of protein phosphorylation, 0048477=oogenesis, 0007155=cell adhesion, 0007423=sensory organ development, 1900087=positive regulation of G1/S transition of mitotic cell cycle, 0007259=JAK-STAT cascade, 0007422=peripheral nervous system development, 0000278=mitotic cell cycle, 0007096=regulation of exit from mitosis, 0007307=eggshell chorion gene amplification, 0043065=positive regulation of apoptotic process" "0005634=nucleus, 0019908=nuclear cyclin-dependent protein kinase holoenzyme complex" "dCyclinE, cyclin-E, CDI7, CyeE, unnamed, cycline E, DmcycE, l35Dd, cyclinE, Cyc E, l(2)br37, Cyclin, l(2)k02602, br37, CYCE, D-CycE, fond, DmcyclinE, Cyclin-dependent kinase interactor 7, l(2)05206, 3938, l(2)k05007, CyclE, cyclin E, cycline, cycE, Cdi7, dCycE, CG3938, Cyclin-E, CycEI, l(2)35Dd, l(2)k02514, fondue, cdi7, BG:DS07108.3, dm-cycE, DmCycE, CyclinE, Cyc" "IPR013763=Cyclin-like, IPR004367=Cyclin, C-terminal domain, IPR006671=Cyclin, N-terminal" CG3938 16-Dec-15 2015_12 WBGene00000871(cye-1) "ENSMUSG00000002068(Ccne1),ENSMUSG00000028212(Ccne2)" " embryonic stage | stage >=10 , embryonic stage , embryonic stage | early , embryonic stage | stage 5 , embryonic stage | stage >10 , embryonic stage | stage 8-11 , embryonic stage | 1-2hr " " Malpighian tubule | restricted

, epidermis | dorsal

, organism | striped

, peripheral nervous system | restricted

, embryonic central nervous system | restricted

, embryonic/larval hindgut

, embryonic central nervous system

, neuroblast

, peripheral nervous system

, anterior embryonic/larval midgut

,

posterior , posterior embryonic/larval midgut

" " larval stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage " " eye-antennal disc | restricted

, lamina anlage

, oocyte

, nurse cell

, larval inner optic anlage

, morphogenetic furrow | posterior to

, larval outer optic anlage

, follicle cell

" "visible,viable,female sterile,neuroanatomy defective,recessive,lethal,lethal - all die during embryonic stage,lethal - all die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,mitotic cell cycle defective,partially,lethal - all die before end of larval stage,sterile,some die during larval stage,fertile,meiotic cell cycle defective,size defective,heat sensitive,homeotic,increased cell number,somatic clone,decreased cell size,wild-type,increased cell death" "neuroblast NB6-4 of thorax,glial cell,ectopic,eye,neuroblast NB6-4a,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,wing vein,ommatidium,ventral nerve cord commissure,macrochaeta,heterochromatin & nurse cell,nurse cell & nucleus,nurse cell,egg chamber,germinal vesicle,oocyte,dorsal appendage,cystocyte,anterior midgut proper primordium & mitotic cell cycle,wing vein L5,larval outer optic anlage,wing,distal,posterior,interommatidial bristle,pigment cell,eye photoreceptor cell,eye disc,wing hair,follicle stem cell,somatic clone,egg,chorion,mitotic cell cycle | ectopic | heat sensitive,extended germ band embryo,heat sensitive,embryonic epidermis,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,eye-antennal disc,S phase | ectopic,morphogenetic furrow,anterior,embryo,wing cell,RP2 motor neuron,neuroblast NB4-2,ganglion mother cell,embryonic hindgut,neuroblast NB6-4 of abdomen,mitotic cell cycle | embryonic stageprd.RG1,G1 phase & external sensory organ precursor cell IIIbneur-P72,tormogen cell,thecogen cell,neuron & embryonic abdomen | ectopic-537.4,glial cell & eye disc | ectopicbi-omb-Gal4,embryonic/larval salivary gland,follicle cell & nucleus | somatic clone,S phase | ectopicF4,larval salivary gland & embryo & nucleusF4,embryonic segment,posterior compartment,wing blade,aCC neuron,pCC neuron,embryonic/larval salivary gland | embryonic stage,presumptive embryonic salivary gland,ommatidial precursor cluster,adult brain,tracheole,cell non-autonomous,macrochaeta & thorax,neuroblast NB6-4" DRSC03295 IEK -4.699781408 -5.940046543 -1.197202356 -5.348837529 7.114616203 7.56278251 FBgn0010328 woc without children http://flybase.net/reports/FBgn0010328.html FBgn0039502 protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0003682=chromatin binding, 0003677=DNA binding" "0016233=telomere capping, 0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis, 0006697=ecdysone biosynthetic process, 0006357=regulation of transcription from RNA polymerase II promoter" "0043234=protein complex, 0005634=nucleus, 0035012=polytene chromosome, telomeric region, 0000792=heterochromatin, 0000791=euchromatin, 0005705=polytene chromosome interband" "Without Children, with out children, Without children, Woc, WOC, CG5965" "IPR017956=AT hook, DNA-binding motif, IPR011017=TRASH domain, IPR021893=Protein of unknown function DUF3504, IPR010507=Zinc finger, MYM-type" CG5965 16-Dec-15 2015_12 "ENSDARG00000035821(si:ch211-173p18.3),ENSDARG00000035823(si:ch211-173p18.1),ENSDARG00000057681" "ENSXETG00000020876(ZMYM3),ENSXETG00000002643(),ENSXETG00000009675()" "ENSMUSG00000042446,ENSMUSG00000021945(Zmym2),ENSMUSG00000031310(Zmym3)" "ENSG00000146463(ZMYM4),ENSG00000121741(ZMYM2),ENSG00000147130(ZMYM3)" "lethal,recessive,viable,fertile,partially lethal - majority die,sterile,visible,female fertile,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,female semi-sterile,lethal - all die before end of larval stage,some die during third instar larval stage" "ring gland,prothoracic gland,nuclear chromosome,hemocyte,embryonic/larval lymph gland,imaginal disc,embryonic/larval brain,embryonic/larval proventriculus,wing,wing vein,eye,chromosome, telomeric region,ganglion mother cell,trichogen cell,polytene chromosome,chromosome, telomeric regionmbtP)" FBgn0002921 Atpë± Na pump ë± subunit http://flybase.net/reports/FBgn0002921.html "FBgn0004667, FBgn0010739, FBgn0010749, FBgn0011344, FBgn0011348, FBgn0011389, FBgn0011518, FBgn0014319, FBgn0024511, FBgn0038844" protein_coding_gene "0008324=cation transmembrane transporter activity, 0005391=sodium:potassium-exchanging ATPase activity, 0005524=ATP binding, 0046872=metal ion binding" "0007626=locomotory behavior, 0007630=jump response, 0001894=tissue homeostasis, 0050905=neuromuscular process, 0009612=response to mechanical stimulus, 0019991=septate junction assembly, 0008340=determination of adult lifespan, 0035152=regulation of tube architecture, open tracheal system, 0008344=adult locomotory behavior, 0008360=regulation of cell shape, 0035158=regulation of tube diameter, open tracheal system, 0007268=synaptic transmission, 0007605=sensory perception of sound, 0006813=potassium ion transport, 0006812=cation transport, 0060439=trachea morphogenesis, 0009266=response to temperature stimulus, 0051124=synaptic growth at neuromuscular junction, 0006814=sodium ion transport, 0001700=embryonic development via the syncytial blastoderm, 0035159=regulation of tube length, open tracheal system" "0005886=plasma membrane, 0005890=sodium:potassium-exchanging ATPase complex, 0016323=basolateral plasma membrane, 0005918=septate junction, 0005634=nucleus, 0005737=cytoplasm" "l(3)04492, Na[+]-K[+]-ATPase alpha[[5]]-subunit, Na[+]-K[+] ATPase, sodium pump alpha-subunit, Na[ +] , K[ +] -ATPase, Na[+], K[+] -ATPase, ATPalpha, Na[+] pump alpha subunit, Na,K-ATPase alpha subunit, l(3)01453, (Na[+] + K[+])-ATPase alpha-subunit, alpha-subunit of ATPase, ATPase alpha subunit, Atpa, Na,K-ATPase alpha, Na pump alpha subunit, Atp a, Na[+]K[+]-ATPase, l(3)j3B7, Na/K-ATPase, Sodium pump alpha subunit, ATP-alpha, dnATPase, Na[+],K[+]-ATPase alpha subunit, Na+,K+ ATPase alpha-subunit, Na[+],K[+]-ATPase alpha-subunit, Na[+]K[+] ATPase, ATPase alpha, Na-p, ATPa, (Na[+]/k[+])-ATPase, l(3)ry136, Na,K-ATPase alpha-subunit, l(3)01164, Na[+]/K[+]-ATPase, Na+-K+-ATPase, Da-47, Na[+], K[+] ATPase alpha, Na, K ATPase a subunit, Na[+]K[+] ATPase alpha subunit, Na/K-ATPase alpha-subunit, (Na[+],K[+])ATPase alpha subunit, Na[+]/K[+] ATPase, Atpalpha, JY, Na[+]/K[+] ATPase alpha subunit, Na,K ATPase, CG5670, l(3)rM454, Na+/K+ ATPase alpha subunit, Na[+],K[+]-ATPase, sodium/potassium transporting ATPase alpha, Na/K ATPase, Na,K ATPase alpha subunit, Na,K-ATPase, Na[+]K[+]ATPase, NaK, l(3)j3B2, Na[+],K[+] ATPase alpha subunit, unnamed, Na[+]/K[+]ATPase, atpalpha, l(3)j6A4, Na[+]/K[+] ATPase (alpha subunit), NaK ATPase, ATPBagr" "IPR023214=HAD-like domain, IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR023298=P-type ATPase, transmembrane domain, IPR001757=P-type ATPase, IPR023299=P-type ATPase, cytoplasmic domain N, IPR005775=P-type ATPase, subfamily IIC, IPR006068=Cation-transporting P-type ATPase, C-terminal, IPR004014=Cation-transporting P-type ATPase, N-terminal" CG5670 16-Dec-15 2015_12 "ENSDARG00000036815(atp1a3b),ENSDARG00000018259(atp1a3a),ENSDARG00000002791(atp1a1),ENSDARG00000019856(atp1a1b),ENSDARG00000001870(atp1a1a.4),ENSDARG00000010472(atp1a2a),ENSDARG00000039131(atp1a1a.3),ENSDARG00000007739(atp1a1a.2)" WBGene00001137(eat-6) "ENSXETG00000023811(ATP1A3),ENSXETG00000020366(atp1a1),ENSXETG00000008125()" "ENSMUSG00000033161(Atp1a1),ENSMUSG00000007097(Atp1a2),ENSMUSG00000040907(Atp1a3),ENSMUSG00000007107" "ENSG00000105409(ATP1A3),ENSG00000163399(ATP1A1),ENSG00000018625(ATP1A2)" " larval stage , embryonic stage -- adult stage , adult stage " " embryonic/larval salivary gland

, abdomen

, larval brain

, head

, thorax

, Malpighian tubule

, adult head

, adult thorax

" adult stage " adult brain

, indirect flight muscle

, thoracico-abdominal ganglion

, optic lobe

, retina

, photoreceptor cell

, Malpighian tubule

, tubular muscle

" "lethal,bang sensitive,dominant,locomotor behavior defective,partially lethal - majority die,neuroanatomy defective,viable,heat sensitive,long lived,short lived,locomotor rhythm defective,fertile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,paralytic,neurophysiology defective,chemical sensitive,hypoactive,conditional,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority live,fully,rescuable maternal effect,cold sensitive,phototaxis defective,chemical resistant,partially,behavior defective,circadian behavior defective,auditory perception defective" "adult brain,thoracico-abdominal ganglion,flight muscle,neuromuscular junction,NMJ bouton,supernumerary,embryonic/first instar larval cuticle,segment,embryonic segment,septate junction,presumptive embryonic/larval tracheal system,ganglionic branch primordium,dorsal trunk primordium,dorsal medial muscle,embryonic/larval dorsal trunk,embryonic/larval ganglionic branch,presumptive embryonic salivary gland,embryonic somatic muscle,tracheal branch primordium,Malpighian tubule,Johnston organ" FBgn0039044 p53 p53 http://flybase.net/reports/FBgn0039044.html "FBgn0051325, FBgn0053336" protein_coding_gene "0001097=TFIIH-class transcription factor binding, 0031624=ubiquitin conjugating enzyme binding, 0000976=transcription regulatory region sequence-specific DNA binding, 0001047=core promoter binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0031625=ubiquitin protein ligase binding, 0008134=transcription factor binding" "2000685=positive regulation of cellular response to X-ray, 0042594=response to starvation, 0071480=cellular response to gamma radiation, 0009411=response to UV, 0040015=negative regulation of multicellular organism growth, 0006974=cellular response to DNA damage stimulus, 0045893=positive regulation of transcription, DNA-templated, 0007405=neuroblast proliferation, 0048477=oogenesis, 0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0009267=cellular response to starvation, 0035234=ectopic germ cell programmed cell death, 0008340=determination of adult lifespan, 0042127=regulation of cell proliferation, 0007131=reciprocal meiotic recombination, 1990248=regulation of transcription from RNA polymerase II promoter in response to DNA damage, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0090278=negative regulation of peptide hormone secretion, 0042246=tissue regeneration, 0006357=regulation of transcription from RNA polymerase II promoter, 0046533=negative regulation of photoreceptor cell differentiation, 0046620=regulation of organ growth, 0014016=neuroblast differentiation, 0006915=apoptotic process, 0042771=intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, 0010212=response to ionizing radiation, 0045787=positive regulation of cell cycle, 0008219=cell death, 0016239=positive regulation of macroautophagy, 0009314=response to radiation, 0006282=regulation of DNA repair, 0030330=DNA damage response, signal transduction by p53 class mediator" "0005634=nucleus, 0035327=transcriptionally active chromatin" "CG31325, D-p53, p53-like regulator of apoptosis and cell cycle, CG10873, protein 53, Dm-P53, dmp53, Drosophila p53, DmP53, DMP53, Dp53, Dmp53, CG33336, dp53, prac" "IPR024631=Transcription factor p53, C-terminal, Drosophila, IPR008967=p53-like transcription factor, DNA-binding, IPR002117=p53 tumour suppressor family, IPR012346=p53/RUNT-type transcription factor, DNA-binding domain, IPR011615=p53, DNA-binding domain" CG33336 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage S10 , embryonic stage | stage 10 , adult stage | female , embryonic stage -- adult stage , embryonic stage | stage 16 , embryonic stage , adult stage , larval stage " " oocyte

, embryonic/larval foregut

, nurse cell

, mesoderm

, germline cell

, embryonic/larval hindgut

, embryonic/larval hindgut | restricted

, embryonic/larval midgut

" "viable,fertile,visible,increased cell death,decreased cell number,germline clone,hyperplasia,lethal - all die before end of pupal stage,decreased cell death,radiation resistant,long lived,RU486 conditional,chemical resistant,conditional,female,neuroanatomy defective,wild-type,mitotic cell cycle defective,size defective,lethal,somatic clone,increased cell size,cell death defective,radiation sensitive,short lived,chemical sensitive,recessive,sterile,partially,aging defective,partially lethal - majority die" "eye,wing,ommatidium,interommatidial bristle,ovary,germline cell,egg chamber,wing disc,oocyte,pole cell,posterior compartment,conditional,neuroblast | larval stage,eye disc,posterior,photoreceptor cell R7,cone cell,posterior | third instar larval stage,photoreceptor cell R7 | third instar larval stage,somatic clone,mitochondrion | somatic clone,embryonic/larval neuroblast,outer photoreceptor cell,neuroblast" FBgn0040068 Vav Vav ortholog (H. sapiens) http://flybase.net/reports/FBgn0040068.html "FBgn0031007, FBgn0062507" protein_coding_gene "0019992=diacylglycerol binding, 0005085=guanyl-nucleotide exchange factor activity, 0030676=Rac guanyl-nucleotide exchange factor activity" "0016477=cell migration, 0007155=cell adhesion, 0035011=melanotic encapsulation of foreign target, 0007015=actin filament organization, 0007411=axon guidance, 0007391=dorsal closure, 0090630=activation of GTPase activity, 0007409=axonogenesis, 0007417=central nervous system development, 0008360=regulation of cell shape, 0072499=photoreceptor cell axon guidance, 0031532=actin cytoskeleton reorganization, 0007520=myoblast fusion, 0007424=open tracheal system development" "CG7893, vav, Vav, BcDNA:GH01128, DmVav, DroVav" "IPR001849=Pleckstrin homology domain, IPR001452=SH3 domain, IPR000219=Dbl homology (DH) domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000980=SH2 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001715=Calponin homology domain" CG7893 16-Dec-15 2015_12 ENSDARG00000044718(LOC556413) YAL041W(CDC24) WBGene00006887(vav-1) "ENSXETG00000019578(vav2),ENSXETG00000007366(VAV1),ENSXETG00000009944(VAV3)" "ENSMUSG00000034116(Vav1),ENSMUSG00000033721(Vav3),ENSMUSG00000009621(Vav2)" "ENSG00000134215(VAV3),ENSG00000141968(VAV1),ENSG00000160293(VAV2)" "neuroanatomy defective,cell migration defective,visible,lethal,recessive,female limited,partially lethal - majority die,male limited,locomotor behavior defective,some die during pupal stage,immune response defective" "embryonic/larval epidermis | embryonic stage,embryonic myoblast,longitudinal connective | embryonic stage,embryonic/larval peripheral nervous system | embryonic stage,longitudinal visceral muscle primordium,embryonic/larval dorsal trunk | embryonic stage,embryonic/larval dorsal branch | embryonic stage,eye,longitudinal connective,midline crossing tract,photoreceptor,lamina,medulla,ellipsoid body,male limited,somatic clone,trichogen cell" FBgn0262332 mir-968 mir-968 stem loop http://flybase.net/reports/FBgn0262332.html miRNA_gene "CR43039, miR-968" CR43039 16-Dec-15 2015_12 "lethal,visible,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing | pharate adult stage,wing,mesothoracic tergum" FBgn0032600 BuGZ Bub3 interacting GLEBS and Zinc finger domain protein http://flybase.net/reports/FBgn0032600.html FBgn0062458 protein_coding_gene "0003677=DNA binding, 0046872=metal ion binding" 0048813=dendrite morphogenesis "Dm_2L:87597, lincRNA.S1359, BcDNA:LD27810, CG17912" "IPR003656=Zinc finger, BED-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG17912 16-Dec-15 2015_12 "ENSDARG00000015538(znf207a),ENSDARG00000015572(znf207b)" WBGene00007105(B0035.1) ENSXETG00000026635(znf207) ENSMUSG00000017421(Zfp207) ENSG00000010244(ZNF207) "neuroanatomy defective,partially lethal - majority die,some die during pupal stage" ventral multidendritic neuron vdaB DRSC02642 E 0.820141082 -0.820133766 0.254625491 -2.534114865 -0.589687324 0.424317235 FBgn0069096 nap napoleon http://flybase.net/reports/FBgn0069096.html gene "0008595=anterior/posterior axis specification, embryo" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic abdomen,germline clone,maternal effect,embryo,posterior" FBgn0032006 Pvr PDGF- and VEGF-receptor related http://flybase.net/reports/FBgn0032006.html protein_coding_gene "0005017=platelet-derived growth factor-activated receptor activity, 0005021=vascular endothelial growth factor-activated receptor activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0005515=protein binding, 0004713=protein tyrosine kinase activity, 0005524=ATP binding" "0007419=ventral cord development, 0048010=vascular endothelial growth factor receptor signaling pathway, 0000022=mitotic spindle elongation, 0045087=innate immune response, 0007435=salivary gland morphogenesis, 0008360=regulation of cell shape, 0043410=positive regulation of MAPK cascade, 0036335=intestinal stem cell homeostasis, 0006468=protein phosphorylation, 0042386=hemocyte differentiation, 0035167=larval lymph gland hemopoiesis, 0007298=border follicle cell migration, 0007443=Malpighian tubule morphogenesis, 0043066=negative regulation of apoptotic process, 0006974=cellular response to DNA damage stimulus, 0030036=actin cytoskeleton organization, 0007516=hemocyte development, 0019730=antimicrobial humoral response, 0007015=actin filament organization, 0035099=hemocyte migration, 0045610=regulation of hemocyte differentiation, 0038202=TORC1 signaling, 0048803=imaginal disc-derived male genitalia morphogenesis, 0035172=hemocyte proliferation, 0030097=hemopoiesis, 0032869=cellular response to insulin stimulus, 0030031=cell projection assembly, 0061327=anterior Malpighian tubule development" 0005886=plasma membrane "VGR1, PDGF- and VEGF-related receptor, Vegfr-b, CG8222, CT24332, Vgr1, VEGFR, stai, 8222, stasis, Vegfr, PDGF/VEGF receptor, PDGF- and VEGF Receptor related, Vegf, platelet-derived growth factor/vascular endothelial growth factor receptor, DmVEGFR, pvr, Vegfr-c, PDGF- and VEGF-Receptor Related, PVF receptor, vgr1, Vascular endothelial growth factor receptor-1 like, VEGFR-A, PVR, Vascular endothelial growth factor receptor, VEGF receptor, PDGF- and VEGF- receptor related" "IPR000719=Protein kinase domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR013783=Immunoglobulin-like fold, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013106=Immunoglobulin V-set domain, IPR013098=Immunoglobulin I-set, IPR017441=Protein kinase, ATP binding site, IPR007110=Immunoglobulin-like domain" CG8222 16-Dec-15 2015_12 "ENSDARG00000015815(kdrl),ENSDARG00000019371(flt1),ENSDARG00000015717(flt4),ENSDARG00000017321(kdr)" "WBGene00006896(ver-3),WBGene00006897(ver-4),WBGene00006894(ver-1)" ENSXETG00000008399(FLT4) "ENSMUSG00000029648(Flt1),ENSMUSG00000062960(Kdr),ENSMUSG00000020357(Flt4)" "ENSG00000102755(FLT1),ENSG00000128052(KDR),ENSG00000037280(FLT4)" " embryonic stage | stage >8 , embryonic stage , larval stage , embryonic stage | stage 11-13 " " embryonic hemocyte

, ventral midline

restricted , larval hemocyte

, embryonic trachea

" " embryonic stage | stage 16 , adult stage " " midline glial cell | subset

, follicle cell

, embryonic hemocyte

" "increased cell death,lethal,recessive,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,somatic clone,temperature conditional,decreased cell size,neuroanatomy defective,tumorigenic,immune response defective,partially,lethal - all die before end of pupal stage,some die during pupal stage,visible,partially lethal - majority die" "Kc167 cell-line,embryonic hemocyte,macrophage,border follicle cell,hemocyte,somatic clone,embryonic/larval hemocyte,ventral nerve cord,embryonic anterior Malpighian tubule,thorax,intestinal stem cell,temperature conditional,enteroblast of posterior adult midgut epithelium,longitudinal connective,embryonic/larval glial cell,presumptive embryonic/larval central nervous system,actin filament | ectopicslbo.2.6,centripetally migrating follicle cell,centripetally migrating follicle cell & actin filamentslbo.2.6,follicle cell,follicle cell & actin filament | somatic clone,hemocyte | larval stage,melanotic mass,lamellocyte,embryonic/first instar larval cuticle,wing disc | larval stage,ventral nerve cord | embryonic stage,border follicle cell & filopodiumslbo.2.6,male terminalia,adult external abdomen,dorsal,male genitalia,dorsal mesothoracic disc & actin filamentptc-559.1,dorsal mesothoracic disc & actin filament & pupa | ectopicBx-MS1096,wing,mesothoracic tergum,microchaeta,actin filament | ectopic,cortical actin cytoskeleton & oocyte associated follicle cellslbo.2.6,adult midgut,enteroendocrine cell,supernumerary,enterocyte,dorsal mesothoracic disc & actin filament | ectopicdpp.blk1,wing disc,trichogen cell,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage" DRSC03080 IEK -3.774866373 -8.350750738 -8.966135791 2.42315247 1.951037086 2.523491109 FBgn0028671 Vha100-1 Vacuolar H+ ATPase 100kD subunit 1 http://flybase.net/reports/FBgn0028671.html FBgn0027533 protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0005516=calmodulin binding, 0009881=photoreceptor activity" "0009416=response to light stimulus, 0048388=endosomal lumen acidification, 0051452=intracellular pH reduction, 0000046=autophagic vacuole fusion, 0015991=ATP hydrolysis coupled proton transport" "0000220=vacuolar proton-transporting V-type ATPase, V0 domain, 0045202=synapse, 0008021=synaptic vesicle, 0005886=plasma membrane, 0005769=early endosome" "Vacuolar H[+] ATPase subunit 100-1, neuron-specific V[[0]] subunit a1, vha100-1, V0, BcDNA:LD21248, vha, Vacuolar ATPase V0, subunit a1, v100, V100, CG1709, v0a1, Vha100-1, V0-ATPase a1" "IPR002490=V-type ATPase, V0 complex, 116kDa subunit family, IPR026028=ATPase, V0 complex, subunit 116kDa, eukaryotic" CG1709 16-Dec-15 2015_12 "ENSDARG00000015174(atp6v0a1b),ENSDARG00000020847(atp6v0a1a)" "YOR270C(VPH1),YMR054W(STV1)" WBGene00006768(unc-32) ENSXETG00000007635(ATP6V0A1) "ENSMUSG00000019302(Atp6v0a1),ENSMUSG00000038600(Atp6v0a4)" "ENSG00000033627(ATP6V0A1),ENSG00000105929(ATP6V0A4)" "visible,phototaxis defective,somatic clone,neurophysiology defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,conditional,lethal,viable" "eye,eye photoreceptor cell,synaptic vesicle & eye photoreceptor cell | somatic clone,eye photoreceptor cell & synapse | somatic clone,photoreceptor cell,rhabdomere | conditional" FBgn0002623 M(3)96C Minute (3) 96C http://flybase.net/reports/FBgn0002623.html gene "M(3)be, M(3R)be, M(3)36e" 16-Dec-15 2015_12 "developmental rate defective,dominant,visible,Minute" "macrochaeta,posterior crossvein,wing,wing vein L2" FBgn0013723 pfy puffy http://flybase.net/reports/FBgn0013723.html gene 16-Dec-15 2015_12 "visible,dominant,female,sex-determination defective,viable,male" "female genitalia,prothoracic leg,female,sex comb,ectopic,polytene chromosome | male" FBgn0001432 l(1)7Ab lethal (1) 7Ab http://flybase.net/reports/FBgn0001432.html gene "jnR2, l(1)jnR2" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0002812 ms(1)V1 male sterile (1) V1 http://flybase.net/reports/FBgn0002812.html gene 16-Dec-15 2015_12 male sterile FBgn0000953 Fs(2)Dor Female sterile (2) Dorog http://flybase.net/reports/FBgn0000953.html gene "Dorog, Fs(2)Sz3" 16-Dec-15 2015_12 "female sterile germline-dependent,dominant" dorsal appendage FBgn0264639 curlicue curlicue http://flybase.net/reports/FBgn0264639.html gene "0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis" 16-Dec-15 2015_12 "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0011656 Mef2 Myocyte enhancer factor 2 http://flybase.net/reports/FBgn0011656.html "FBgn0010437, FBgn0019710, FBgn0047353" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity, 0003677=DNA binding, 0004222=metalloendopeptidase activity, 0001158=enhancer sequence-specific DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0001205=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0007517=muscle organ development, 0006366=transcription from RNA polymerase II promoter, 0007519=skeletal muscle tissue development, 0045475=locomotor rhythm, 0016202=regulation of striated muscle tissue development, 0007520=myoblast fusion, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0052576=carbohydrate storage, 0007496=anterior midgut development, 0019730=antimicrobial humoral response, 0019915=lipid storage, 0007498=mesoderm development, 0010468=regulation of gene expression, 0006355=regulation of transcription, DNA-templated, 0030707=ovarian follicle cell development, 0007507=heart development, 0048747=muscle fiber development" 0005634=nucleus "Myocyte Enhancer Factor-2, mef2, Mef-2, DMef-2, DMEF2, SD04091, Myocyte Enhancing Factor 2, dMef2, mef2c, mef, DMEF-2, myocyte enhancer factor 2, Drosophila myocyte-specific enhancer factor 2, mb247, unnamed, Group C, Drosophila-myocyte enhancer factor 2, l(2)46CFr, Myocyte enhancer factor 2, DMedf2, BEST:SD04091, MEF-2, C, Dmef, CG1429, Dmef-2, Myocyte enhancing factor 2, D-mef2, Dmef2, dmef2, 22.21, Myocyte-enhancer factor-2, Myocyte enhancer factor-2, Mef, D-Mef2, dMEF2, D-MEF2, Myocyte-specific enhancer factor 2, myocyte enhancer factor-2, DMef2, mef-2, dMEf2, myocyte-specific enhancer factor 2, MEF2, Myocyte-enhancer factor 2, Complementation group C" "IPR019503=Peptidase M66 domain, IPR002100=Transcription factor, MADS-box, IPR022102=Holliday junction regulator protein family C-terminal" CG1429 16-Dec-15 2015_12 "ENSDARG00000057527,ENSDARG00000031756(mef2a),ENSDARG00000040237(mef2d),ENSDARG00000009418(mef2cb)" "YBR182C(SMP1),YPL089C(RLM1)" WBGene00003182(mef-2) "ENSXETG00000007038(MEF2C),ENSXETG00000018788(MEF2A),ENSXETG00000020378(MEF2D)" "ENSMUSG00000030557(Mef2a),ENSMUSG00000001419(Mef2d),ENSMUSG00000005583(Mef2c)" "ENSG00000068305(MEF2A),ENSG00000081189(MEF2C),ENSG00000116604(MEF2D)" " embryonic stage , embryonic stage | stage 13 , embryonic stage | stage >10 , embryonic stage | late , embryonic stage | stage 10 , embryonic stage | stage 5 , embryonic stage -- adult stage , adult stage , embryonic stage | stage 5-9 , embryonic stage | extended germ band , embryonic stage | stage 6,7 " " cardioblast

, embryonic/larval heart

, embryonic somatic muscle

, visceral mesoderm

, embryonic visceral muscle

, embryonic visceral muscle | precursor

, larval visceral muscle

, pharyngeal muscle | precursor

, embryonic somatic muscle | precursor

, somatic mesoderm

,

pair rule , embryonic/larval dorsal vessel

, mesoderm

, mesoderm | primordium

, ventral furrow

, embryonic/larval somatic muscle

, embryonic fat body

, pericardial cell

" " embryonic stage | stage 6 , embryonic stage | extended germ band , embryonic stage | late , embryonic stage | mid , embryonic stage | stage >=11 , embryonic stage | stage >=10 , embryonic stage | stage 13 , embryonic stage | stage 6-10 , embryonic stage | stage 14 " " ventral furrow

, mesoderm

, pharyngeal muscle

, somatic mesoderm

, head mesoderm

, cardioblast

, visceral mesoderm

, visceral muscle

, larval visceral muscle

, embryonic/larval somatic muscle

, embryonic/larval dorsal vessel

, embryonic myoblast

, somatic muscle

, embryonic/larval heart

, mesoderm | segmentally repeated

" "lethal,partially,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,short lived,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,locomotor rhythm defective,heat sensitive,flightless,viable,female sterile,polyphasic,partially lethal - majority die,flight defective" "embryonic/larval muscle system,gastric caecum primordium,adult somatic muscle,mesothoracic extracoxal depressor muscle 66,dorsal medial muscle | pupal stage,indirect flight muscle | pupal stage,embryonic/larval cardial cell,embryonic/larval somatic muscle,embryonic/larval midgut,embryonic visceral muscle,muscle fiber,myoblast,muscle founder cell,embryonic myoblast,neuromuscular junction | embryonic stage,tormogen cell,presumptive embryonic/larval muscle system,heat sensitive,lateral transverse muscle,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,embryonic/larval dorsal vessel,dorsal medial muscle,coxal tergal remotor muscle,lateral oblique dorsal muscle,tergosternal muscle,somatic muscle,embryonic/larval heart,intersegmental nerve,pharyngeal muscle,midgut constriction,muscle attachment site,A1-7 dorsal acute muscle 1,egg,dorsal appendage,centripetally migrating follicle cell,oblique muscle,anterior embryonic/larval midgut,gastric caecum,denticle belt,embryonic/first instar larval cuticle,dorsal closure embryo,trachea,embryonic epidermis,embryonic/larval midgut | embryonic stage,cardioblast,embryonic/larval pericardial cell,A1-7 lateral transverse muscle,A1-7 lateral transverse muscle 4,eye,adult head,antenna,wing,trichogen cell,mesothoracic tergum" FBgn0021750 Aats-ser Seryl-tRNA synthetase http://flybase.net/reports/FBgn0021750.html protein_coding_gene "0005524=ATP binding, 0004828=serine-tRNA ligase activity" "0070158=mitochondrial seryl-tRNA aminoacylation, 0006434=seryl-tRNA aminoacylation" 0005737=cytoplasm "DmSRS2, SRS, unnamed, CG4938, seryl-tRNA synthetase, SerRS, Aat-Ser" "IPR002317=Serine-tRNA ligase, type1, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR002314=Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)" CG4938 16-Dec-15 2015_12 ENSDARG00000020115(sars2) YHR011W(DIA4) WBGene00005662(sars-2) ENSXETG00000005332(SARS2) ENSMUSG00000070699(Sars2) ENSG00000104835(FBXO17) embryonic stage embryonic/larval salivary gland

"lethal,visible,heat sensitive,short lived,locomotor behavior defective" "wing,1st posterior cell,anterior crossvein,mitochondrion, with Dcr-2UAS.cDa, ,mitochondrial matrix, with Dcr-2UAS.cDa, ,mitochondrial crista, with Dcr-2UAS.cDa, " FBgn0000180 bib big brain http://flybase.net/reports/FBgn0000180.html protein_coding_gene "0015267=channel activity, 0005372=water transmembrane transporter activity, 0005261=cation channel activity, 0005216=ion channel activity" "0016337=single organismal cell-cell adhesion, 0044719=regulation of imaginal disc-derived wing size, 0007219=Notch signaling pathway, 0007399=nervous system development, 0007498=mesoderm development, 0030707=ovarian follicle cell development, 0055085=transmembrane transport, 0046331=lateral inhibition, 0007398=ectoderm development" "0031410=cytoplasmic vesicle, 0005887=integral component of plasma membrane, 0005912=adherens junction, 0005886=plasma membrane, 0016021=integral component of membrane" "Bib, l(2)neo91, Big brain, m-bib, l(2)neo66, EP(2)2278, CG4722, BIB_DROME" "IPR023271=Aquaporin-like, IPR022357=Major intrinsic protein, conserved site, IPR000425=Major intrinsic protein" CG4722 16-Dec-15 2015_12 "ENSG00000165269(AQP7),ENSG00000181997,ENSG00000186466,ENSG00000176115,ENSG00000165272(AQP3),ENSG00000103569(AQP9),ENSG00000143595(AQP10)" " embryonic stage | stage 5 , embryonic stage | stage 9-12 , embryonic stage | stage 5-12 " " organism | ubiquitous

, mesoderm

, organism

, ectoderm | restricted

" " embryonic stage | stage 13-15 , embryonic stage | stage 7 , larval stage | third instar , pupal stage | 24 hr , embryonic stage | stage 13 , embryonic stage | stage >=7 , embryonic stage | stage 11 , embryonic stage | stage 16 " " posterior embryonic/larval midgut

, amnioproctodeal invagination

, proneural cluster &&of dorsal mesothoracic disc

, eo neuron

, tormogen cell

, stomodeal invagination

, embryonic/larval dorsal vessel

, ectoderm

, epidermis

, ventral midline

, trichogen cell

, Malpighian tubule

, pupal epidermis

, sense organ &&of dorsal mesothoracic disc

, flight muscle | precursor

, embryonic/larval tracheal pit

, ventral nervous system | subset

, wing vein | precursor

, thecogen cell

, amnioserosa

, adepithelial cell of dorsal mesothoracic disc | restricted

, adult myoblast | precursor

" "visible,lethal,neurogenic phenotype,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,neuroanatomy defective,viable,body color defective,size defective" "scutellar bristle,ectopic,macrochaeta,embryonic epidermis,eye photoreceptor cell,somatic clone,supernumerary,rhabdomere | somatic clone | supernumerary,multidendritic neuron,embryonic/larval dorsal vessel,precursor,embryonic/larval salivary gland,embryonic Malpighian tubule,stomatogastric nervous system,optic lobe,embryonic/larval somatic muscle,neuroblast,cardioblast,sensory mother cell,peripheral glial cell,presumptive embryonic/larval central nervous system,microchaeta,presumptive embryonic/larval nervous system,embryonic myoblast,embryonic/larval nervous system,embryonic/larval oenocyte precursor,nervous system,ventral,embryonic/first instar larval cuticle,ectoderm,germline clone,sense organ,chaeta,mesothoracic tergum,wing,posterior" FBgn0000719 fog folded gastrulation http://flybase.net/reports/FBgn0000719.html "FBan0009559, FBgn0069907, FBgn0069908, FBgn0069909, FBtr0077342, FBpp0077034" protein_coding_gene "0007362=terminal region determination, 0008360=regulation of cell shape, 0007369=gastrulation, 0003384=apical constriction involved in gastrulation, 0007370=ventral furrow formation, 0007435=salivary gland morphogenesis, 0007472=wing disc morphogenesis, 0007374=posterior midgut invagination, 0040034=regulation of development, heterochronic, 0007509=mesoderm migration involved in gastrulation, 0008293=torso signaling pathway, 0070252=actin-mediated cell contraction, 0016331=morphogenesis of embryonic epithelium, 0021782=glial cell development, 0007399=nervous system development, 0007498=mesoderm development, 0000266=mitochondrial fission, 0007411=axon guidance, 0007476=imaginal disc-derived wing morphogenesis" "0005576=extracellular region, 0005737=cytoplasm" "l(1)114, Folded gastrulation, l(1)16-3-190, CR41108, CR41110, l114, M67, CG9559, CR41109, Fog, l(1)20Ba, 114" CG9559 16-Dec-15 2015_12 " embryonic stage | stage 6 , embryonic stage | stage 5 " "

posterior , posterior midgut proper primordium

,

ventral , ventral furrow

,

dorsal ,

0-10% egg length " "some die during first instar larval stage,some die during second instar larval stage,lethal - all die before end of larval stage,neuroanatomy defective,wild-type,cell migration defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,partially,developmental rate defective,viable,visible" "posterior embryonic/larval midgut,interface glial cell,glial cell projectionrepo,segmental nerve branch SNa of A1-7,fascicle,embryonic/larval central nervous system,motor neuron,glial cell projectionhtl.POS,embryonic head,dorsal,embryo,lateral,ventral furrow,amnioproctodeal invagination,salivary gland,mesoderm,embryonic/larval hindgut,Malpighian tubule,extended germ band embryo,posterior endoderm,posterior midgut primordium,presumptive embryonic salivary gland,endoderm,ventral midline,hub cell,adherens junctionmat.ë±Tub67C.THsimVP16,wing disc,wing,chaeta,supernumerary,mesothoracic tergum" FBgn0015222 Fer1HCH Ferritin 1 heavy chain homologue http://flybase.net/reports/FBgn0015222.html "FBgn0010717, FBgn0011426, FBgn0039762, FBgn0043793" protein_coding_gene "0008199=ferric iron binding, 0008198=ferrous iron binding" "1990461=detoxification of iron ion, 0097459=iron ion import into cell, 0006879=cellular iron ion homeostasis, 0009791=post-embryonic development, 0009620=response to fungus, 0008283=cell proliferation" "0005576=extracellular region, 0008043=intracellular ferritin complex, 0005875=microtubule associated complex, 0005794=Golgi apparatus, 0045169=fusome" "Ferritin H, ferritin HCH, CG2216, 1HCH, BEST:LD36673, ferritin H, fer1hch, ferritin 1 heavy chain homolog, Fer1, Ferritin-Heavy, FER1, Ferritin, Fer1HC, ferritin 1 heavy chain, Fer-L, fer1, Fe1HCH, T9, ferritin subunit 1, HCH, T21, FerHCH, unnamed, Ferritin 1 heavy chain, l(3)j10B4, ferritin heavy chain, ferritin, l(3)00451, Ferritin-Light, FER1HCH" "IPR008331=Ferritin/DPS protein domain, IPR009040=Ferritin- like diiron domain, IPR001519=Ferritin, IPR009078=Ferritin-like superfamily, IPR012347=Ferritin-related" CG2216 16-Dec-15 2015_12 "lethal,recessive,female fertile,germline clone,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority live,small body,visible,partially lethal - majority die,some die during pupal stage,circadian rhythm defective,gravitaxis defective,progressive,locomotor rhythm defective" "trichogen cell,mesothoracic tergum" FBgn0027948 msps mini spindles http://flybase.net/reports/FBgn0027948.html FBgn0044745 protein_coding_gene "0005515=protein binding, 0015631=tubulin binding, 0008017=microtubule binding" "0007067=mitotic nuclear division, 0045450=bicoid mRNA localization, 0007143=female meiotic division, 0007344=pronuclear fusion, 0007411=axon guidance, 0007029=endoplasmic reticulum organization, 0016325=oocyte microtubule cytoskeleton organization, 0048477=oogenesis, 0090063=positive regulation of microtubule nucleation, 0007017=microtubule-based process, 0000022=mitotic spindle elongation, 0031122=cytoplasmic microtubule organization" "0005813=centrosome, 0035371=microtubule plus-end, 0005875=microtubule associated complex, 0000922=spindle pole" "Dis1, Mini spindles, MINISPINDLES, TOG, CG5000, XMAP215, Mini-spindles, MSPS, minispindles, mini-spindles, Minispindles, Mini Spindles, Msps, anon-WO0140519.136" "IPR021133=HEAT, type 2, IPR024395=CLASP N-terminal domain, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG5000 16-Dec-15 2015_12 ENSDARG00000005446(ckap5) WBGene00006994(zyg-9) ENSXETG00000001986(CKAP5) ENSMUSG00000040549(Ckap5) ENSG00000175216(CKAP5) "size defective,heat sensitive,neuroanatomy defective,female sterile,viable,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,mitotic cell cycle defective,partially lethal - majority die,visible" "retina,heat sensitive,MP1 neuron,lateral longitudinal fascicle,intersegmental nerve branch ISNb of A1-7,nurse cell & microtubule,oocyte & microtubule,follicle cell & microtubule,oocyte,microtubule & nurse cell | oogenesis stage S8,microtubule & nurse cell | oogenesis stage S9,microtubule & nurse cell | oogenesis stage S10B,microtubule & oocyte | oogenesis stage S10B,oocyte nucleus,mitotic cell cycle,mitotic anaphase,mitotic anaphase & nuclear chromosome,mitotic cell cycle & spindle,cytoplasmic microtubule & embryonic/larval hemocyte,spindle,spindle pole,cytoplasmic microtubule,pronucleus,eye,macrochaeta,adult cuticle & abdomen,oocyte & spindle,mesothoracic tergum" FBgn0262446 mir-137 mir-137 stem loop http://flybase.net/reports/FBgn0262446.html "FBgn0082181, FBgn0262305" miRNA_gene "miR-137, 2R:11128979, CR43012, mir-137, dme-mir-318, CR33575, dme-mir-137" CR43012 16-Dec-15 2015_12 "visible,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" "wing vein,wing margin,wing" FBgn0013563 Pex1 Peroxin 1 http://flybase.net/reports/FBgn0013563.html "FBgn0024587, FBgn0026223, FBgn0028085, FBgn0036409, FBgn0046338, FBgn0046339, FBgn0046340, FBgn0046489, FBgn0046490, FBgn0046491" protein_coding_gene "0042623=ATPase activity, coupled, 0005524=ATP binding" "0007031=peroxisome organization, 0007422=peripheral nervous system development, 0048137=spermatocyte division, 0021782=glial cell development, 0007417=central nervous system development, 0006625=protein targeting to peroxisome" "0005778=peroxisomal membrane, 0005777=peroxisome" "l(3)02402, PEX1, DmCAB51031.1, anon-WO0172774.99, anon-WO0172774.101, pex1, anon-WO0172774.100, anon-WO0172774.102, CG6760, anon-WO0172774.96, l(3)70Da, 0848/07, peroxin 1, l(3)S084807, lethal (3) 70Da, l(3)s4868, DmelPex1, l(3)084807, anon-WO0172774.98" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR029067=CDC48 domain 2-like, IPR025653=Peroxisome biogenesis factor 1, IPR015342=Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR009010=Aspartate decarboxylase-like domain" CG6760 16-Dec-15 2015_12 YKL197C(PEX1) WBGene00004191(prx-1) ENSXETG00000003420(PEX1) ENSMUSG00000005907(Pex1) ENSG00000127980(PEX1) "lethal,recessive,cytokinesis defective,meiotic cell cycle defective,body size defective,locomotor behavior defective,developmental rate defective,feeding behavior defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,increased cell death,partially lethal - majority die,viable" "spermatid,testis,ventral nerve cord,peripheral nervous system,central nervous system,eye-antennal disc primordium,embryonic brain,Malpighian tubule primordium,anterior spiracle primordium,posterior spiracle primordium,embryonic/larval glial cell,embryonic/larval salivary gland" FBgn0002344 l(3)87Bm lethal (3) 87Bm http://flybase.net/reports/FBgn0002344.html gene l(3)ck25 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0011327 Uch-L5 Ubiquitin carboxy-terminal hydrolase L5 ortholog http://flybase.net/reports/FBgn0011327.html "FBgn0027061, FBgn0028558" protein_coding_gene "0004843=ubiquitin-specific protease activity, 0008242=omega peptidase activity" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination, 0022008=neurogenesis, 0006511=ubiquitin-dependent protein catabolic process" "0005838=proteasome regulatory particle, 0005737=cytoplasm, 0005634=nucleus, 0000502=proteasome complex" "Ubiquitin C-terminal hydrolase, BcDNA:LD24440, CG3431, l(3)j2B8, p37A, UCH, dUCH37, uch-L3, BcDNA.LD24440, ubiquitin C-terminal hydrolase, Uch37, Uch-L3, Ubiquitin C-terminal hydrolase related, UCH 37, Q9XZ61" "IPR001578=Peptidase C12, ubiquitin carboxyl-terminal hydrolase, IPR017390=Ubiquitinyl hydrolase, UCH37 type" CG3431 16-Dec-15 2015_12 ENSDARG00000042635(uchl5) WBGene00006724(ubh-4) ENSXETG00000017223(UCHL5) ENSMUSG00000018189(Uchl5) ENSG00000116750(UCHL5) "lethal,short lived,lethal - all die before end of pupal stage,some die during pupal stage,recessive,partially lethal - majority die,visible,neuroanatomy defective,viable" "eye,wing hair,wing,tarsal segment & joint & pharate adult,leg,fourth segment of antenna,arista,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0060597 l(3)S092006b lethal (3) S092006b http://flybase.net/reports/FBgn0060597.html gene 0920/06 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0030574 CG9413 http://flybase.net/reports/FBgn0030574.html protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport 0016020=membrane IPR002293=Amino acid/polyamine transporter I CG9413 16-Dec-15 2015_12 ENSDARG00000005894(slc7a9) "YGR055W(MUP1),YHL036W(MUP3)" ENSXETG00000018268(SLC7A9) ENSMUSG00000030492(Slc7a9) ENSG00000021488(SLC7A9) "viable,fertile,lethal,recessive" FBgn0027977 l(3)S139101 lethal (3) S139101 http://flybase.net/reports/FBgn0027977.html gene 1391/01 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0004138 l(2)43Eg lethal (2) 43Eg http://flybase.net/reports/FBgn0004138.html gene 16-Dec-15 2015_12 lethal FBgn0003206 Ras64B Ras oncogene at 64B http://flybase.net/reports/FBgn0003206.html FBgn0063029 protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding, 0019003=GDP binding" 0007265=Ras protein signal transduction 0016020=membrane "ras-2, BcDNA:RE36103, Ras, D-ras2, RAS2, Dmras64B, small GTP binding protein, RAS64B, c-ras2, D-ras-2, DRas2, CG1167, Ras2, ras2, C-ras2, ras, Dras64B, Dm-ras-64B, RAS, ras oncogene, Dras2" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020849=Small GTPase superfamily, Ras type, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG1167 16-Dec-15 2015_12 ENSDARG00000036252(rras2) WBGene00004310(ras-1) ENSXETG00000005505(MRAS) ENSMUSG00000055723(Rras2) ENSG00000133818(RRAS2) " adult stage , larval stage | third instar , embryonic stage " " adult brain | resticted

, dorsal mesothoracic disc

, thoracico-abdominal ganglion

, eye-antennal disc

, garland cell

, embryonic central nervous system

, antenno-maxillary complex

, larval brain | restricted

, genital disc

" "lethal,maternal effect,visible,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,cell polarity defective,female,lethal - all die before end of pupal stage,some die during pupal stage,small body,heat sensitive,viable" "ommatidium,maternal effect,dorsal triple row,medial triple row,ventral triple row,anterior sternopleural bristle,middle sternopleural bristle,posterior sternopleural bristle,ventral sternopleural bristle,upper humeral bristle,lower humeral bristle,humeral sclerite,ventral wing blade,dorsal wing blade,embryonic head,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,eye,photoreceptor cell,wing vein,ectopic,wing" DRSC08689 IE -0.179531449 -2.164211685 -2.53675042 -2.056523671 -0.520522795 -1.37855724 FBgn0069336 UY2635 UY2635 http://flybase.net/reports/FBgn0069336.html gene unnamed 16-Dec-15 2015_12 "neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell,mushroom body & axonc739,mushroom body beta-lobe" FBgn0000497 ds dachsous http://flybase.net/reports/FBgn0000497.html protein_coding_gene "0005509=calcium ion binding, 0045296=cadherin binding, 0004872=receptor activity, 0050839=cell adhesion molecule binding, 0004871=signal transducer activity" "0007480=imaginal disc-derived leg morphogenesis, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0090175=regulation of establishment of planar polarity, 0035159=regulation of tube length, open tracheal system, 0045198=establishment of epithelial cell apical/basal polarity, 0035222=wing disc pattern formation, 0044331=cell-cell adhesion mediated by cadherin, 0030010=establishment of cell polarity, 0000904=cell morphogenesis involved in differentiation, 0007476=imaginal disc-derived wing morphogenesis, 0008283=cell proliferation, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0016318=ommatidial rotation, 0048592=eye morphogenesis, 0045317=equator specification, 0042067=establishment of ommatidial planar polarity, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0018149=peptide cross-linking, 0007164=establishment of tissue polarity, 0090176=microtubule cytoskeleton organization involved in establishment of planar polarity, 0016337=single organismal cell-cell adhesion, 0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity" "0005887=integral component of plasma membrane, 0005886=plasma membrane, 0016021=integral component of membrane" "Daschous, Ds, dachs, Dachsous, cad2, l(2)05142, CG17941, CT39575, EP-822, cadherin-2" "IPR020894=Cadherin conserved site, IPR002126=Cadherin, IPR015919=Cadherin-like" CG17941 16-Dec-15 2015_12 ENSDARG00000056655 WBGene00019994(cdh-1) ENSXETG00000001810(DCHS2) ENSG00000166341(DCHS1) " larval stage | third instar , embryonic stage | stage 16 , embryonic stage | stage 14 , embryonic stage | stage 11 , embryonic stage | stage 10 , embryonic stage | stage 6 " " scabellum &&of haltere | anlagen

, labial disc

, antennal segment 1 | anlagen

, eye-antennal disc

, intersegmental apodeme

, frontal head air sac | anterior

, mushroom body

, arista | anlagen

, genital disc

, dorsal prothoracic disc

, embryonic/larval anterior spiracle

, ventral thoracic disc

, larval labral segment sense organ

, intercalary segment

, ventral thoracic disc | presumptive

, labial organ

, tracheal pit

, antennal segment 2 | anlagen

, procephalic segment

, labrum

, dorsal metathoracic disc

,

segment polarity , optic lobe

, dorsopharyngeal organ

, haltere pedicel | anlagen

, dorsal mesothoracic disc

, organism | pair rule

, mesothoracic pleurum | anlagen

, capitellum &&of haltere | anlagen

, postpronotum | anlagen

" "visible,planar polarity defective,viable,fertile,lethal,recessive,size defective,cell polarity defective,cell non-autonomous,somatic clone,heat sensitive,reduced,female sterile,cell shape defective,increased cell number,some die during immature adult stage,hyperplasia,male fertile,cold sensitive" "wing,wing vein,chaeta,ectopic,wing hair,leg,thorax,eye,anterior crossvein,tarsal segment,joint,tegula,humeral sclerite,wing hinge,costal vein,wing margin,anterior,posterior,scutum,scutellum,wing disc,crossvein,wing blade,proximal,glial cell & larval optic lobe,axon & larval optic lobe,trichome & abdominal tergite | somatic clone | cell non-autonomousë±Tub84B.PL,denticle belt,heat sensitive,trichome & abdominal tergite,coxa,ommatidium,eye equator,microtubule,somatic clone,eye disc,adult fat body,photoreceptor cell R3,photoreceptor cell R4,adult cuticle,microchaeta,macrochaeta,tergite,cell non-autonomous,embryonic/larval dorsal trunk,adult abdomen,costal vein & trichome,anterior compartment,posterior compartment,cold sensitive,posterior crossvein,wing hair & wing basal cellsalm-459.2,denticle row 2,denticle row 3,denticle row 1,mesothoracic tergum" DRSC00815 K 0.91954613 -0.348848985 -0.109239953 -0.030905422 -0.535949543 1.834294955 FBgn0031057 Ubqn Ubiquilin http://flybase.net/reports/FBgn0031057.html "FBgn0019902, FBgn0045787" protein_coding_gene 0070628=proteasome binding 0042982=amyloid precursor protein metabolic process 0005829=cytosol "Chap, dUbqln, Ubiquilin, Ubqn, BEST:LD26923, dUbqn, ubiquilin, clone 5.42, ubiquilin 1, unnamed, DSK2, UBQLN1, ubqn, CG14224, UBQLN homolog, anon-18DEa, Dsk2" "IPR006636=Heat shock chaperonin-binding, IPR015940=Ubiquitin-associated domain, IPR000626=Ubiquitin domain, IPR009060=UBA-like, IPR015496=Ubiquilin, IPR029071=Ubiquitin-related domain" CG14224 16-Dec-15 2015_12 ENSDARG00000052975(ubin) WBGene00008852(F15C11.2) "ENSXETG00000016764(ubqln1),ENSXETG00000020399(ubqln4)" "ENSMUSG00000005312(Ubqln1),ENSMUSG00000050148(Ubqln2),ENSMUSG00000008604(Ubqln4)" "ENSG00000135018(UBQLN1),ENSG00000188021(UBQLN2),ENSG00000160803(UBQLN4)" "lethal - all die before end of P-stage,some die during pharate adult stage,lethal,short lived,male limited,increased cell death,neuroanatomy defective,partially lethal - majority die,visible,viable" "air bubble | pharate adult stage,head | pharate adult stage,eye | pharate adult stage,leg | pharate adult stage,wing | pharate adult stage,wing vein,ectopic,neuropil,wing vein L4,wing vein L5,anterior crossvein,posterior crossvein,wing vein L3,wing margin,wing cell,wing,crossvein,eye photoreceptor cell,pigment cell,trichogen cell,mesothoracic tergum" FBgn0015989 l(2)PC4-S lethal (2) PC4-S http://flybase.net/reports/FBgn0015989.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0001689 l(1)ESHS10 lethal (1) ESHS10 http://flybase.net/reports/FBgn0001689.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0005632 faf fat facets http://flybase.net/reports/FBgn0005632.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 0005515=protein binding" "0008583=mystery cell differentiation, 0050829=defense response to Gram-negative bacterium, 0016579=protein deubiquitination, 0007349=cellularization, 0008354=germ cell migration, 0035192=nuclear cortical migration, 0009950=dorsal/ventral axis specification, 0006897=endocytosis, 0045824=negative regulation of innate immune response, 0045861=negative regulation of proteolysis, 0006511=ubiquitin-dependent protein catabolic process" 0005737=cytoplasm "fat-facets, CG1945, BcDNA:LD22582, BcDNA.LD22582, P55824, Fat facets, Fat, Faf, Fat Facets" "IPR018200=Ubiquitin specific protease, conserved site, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR016024=Armadillo-type fold, IPR028889=Ubiquitin specific protease domain" CG1945 16-Dec-15 2015_12 ENSDARG00000013708(usp9) ENSXETG00000015489() "ENSMUSG00000031010(Usp9x),ENSMUSG00000069044(Usp9y)" "ENSG00000124486(USP9X),ENSG00000114374(USP9Y)" adult stage && oogenesis stage " nurse cell

, germarium

" " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S10 , larval stage , larval stage | third instar , oogenesis stage&&larval stage , larval stage&&spermatogenesis " " nurse cell

, oocyte | posterior

, eye-antennal disc

, morphogenetic furrow | anterior to

, ovary

, testis

, embryonic/larval digestive system

" "visible,neurophysiology defective,neuroanatomy defective,viable,recessive,female sterile,wild-type,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,partially lethal - majority die,maternal effect" "rhabdomere R7,dorsocentral bristle,trichogen cell,scutellar bristle,adult abdominal sensillum & trichogen cell-537.4,synapse,bouton,supernumerary,synapse | supernumerary,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,anterior fascicle & bouton,neuromuscular junction,wing sensillum,ectopic,adult mushroom body,eye,ommatidium,giant fiber neuron,tergotrochanteral muscle motor neuron,synapseOK307,synaptic vesicle,embryonic/larval central nervous system,neurite | pharate adult stage,embryonic/first instar larval cuticle,non-rescuable maternal effect,embryonic head,filzkorper,cone cell,eye photoreceptor cell,syncytial blastoderm embryo,maternal effect,denticle belt,eye photoreceptor cell & ommatidium | ectopic | somatic clone,denticle,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,pole cell" FBgn0001790 l(1)Mb15 lethal (1) Mb15 http://flybase.net/reports/FBgn0001790.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053514 CG33514 http://flybase.net/reports/FBgn0053514.html "FBgn0035535, FBgn0035536" protein_coding_gene "0005215=transporter activity, 0008431=vitamin E binding" "0022008=neurogenesis, 0006810=transport" 0005622=intracellular "CG15017, CG15018" "IPR001071=Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251=CRAL-TRIO lipid binding domain, IPR011074=CRAL/TRIO, N-terminal domain" CG33514 16-Dec-15 2015_12 "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell" DRSC08471 K -0.344285829 -0.857186342 0.641568006 -0.887781557 -1.677563834 -0.928097129 FBgn0014010 Rab5 Rab5 http://flybase.net/reports/FBgn0014010.html FBgn0022048 protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding" "0007298=border follicle cell migration, 0007349=cellularization, 0035088=establishment or maintenance of apical/basal cell polarity, 0016321=female meiosis chromosome segregation, 0015031=protein transport, 0008285=negative regulation of cell proliferation, 0007067=mitotic nuclear division, 0048813=dendrite morphogenesis, 0006897=endocytosis, 0048803=imaginal disc-derived male genitalia morphogenesis, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0048227=plasma membrane to endosome transport, 0016192=vesicle-mediated transport, 0035220=wing disc development, 0007220=Notch receptor processing, 0030100=regulation of endocytosis, 0016189=synaptic vesicle to endosome fusion, 0032482=Rab protein signal transduction, 0050803=regulation of synapse structure or activity, 0007409=axonogenesis, 0048675=axon extension, 0046664=dorsal closure, amnioserosa morphology change, 0048488=synaptic vesicle endocytosis, 0006325=chromatin organization, 0048477=oogenesis, 0016348=imaginal disc-derived leg joint morphogenesis, 0034058=endosomal vesicle fusion" "0005886=plasma membrane, 0045202=synapse, 0043025=neuronal cell body, 0005769=early endosome, 0005811=lipid particle, 0031982=vesicle" "DmRab5, BAA88244, Rab-5, RAB5a, RAB5, Rab, AAF51265, Drab5, CG3664, DRab5, drab5, Dm Rab5, dRab5, rab5, Rab-protein 5, l(2)k08232" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG3664 16-Dec-15 2015_12 "ENSDARG00000018602(rab5aa),ENSDARG00000007257(rab5ab),ENSDARG00000026712(rab5c)" "YOR089C(VPS21),YNL093W(YPT53)" WBGene00004268(rab-5) "ENSXETG00000014007(rab5c),ENSXETG00000002305(rab5a),ENSXETG00000006194(Q6DJ60_XENTR)" "ENSMUSG00000017831(Rab5a),ENSMUSG00000019173(Rab5c),ENSMUSG00000000711(Rab5b)" "ENSG00000144566(RAB5A),ENSG00000108774(RAB5C),ENSG00000111540(RAB5B)" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal,recessive,partially lethal - majority die,fertile,poor,flightless,locomotor behavior defective,meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,paralytic,hyperplasia,somatic clone,large body,neuroanatomy defective,increased cell growth,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,viable,increased cell death,body color defective" "crystal cell,synaptic vesicle & larval neuromuscular junction,mitosis & nuclear chromosome,endosomeneur-P72,sensory mother cell,external sensory organ precursor cell IIb,external sensory organ precursor cell IIa,supernumerary,adult cuticle,presumptive embryonic/larval nervous system,germline clone,endosome & embryonic nervous system,follicle cell,somatic clone,eye-antennal disc,eye disc,wing disc,yolk granule | germline clone,egg,endocytic vesicle | germline clone,dendrite | somatic clone | third instar larval stage,axon | somatic clone | third instar larval stage,eye photoreceptor cell,synapseGMR.PF,axon terminusGMR.PF,photoreceptor cell,synapsehs.PS,endosomehs.PS,photoreceptor cell & synaptic vesiclehs.PS,nerve terminal & synaptic vesicle,dendrite | third instar larval stageppk.1.9,axon | third instar larval stageppk.1.9,syncytial blastoderm embryo,synaptic vesiclehs.PS,nerve terminal & synaptic vesiclehs.PS,wing margin bristle,ectopic,egg chamber & basement membrane | apicalslbo.2.6,border follicle cell,polar follicle cell,endocytic vesicleslbo.2.6,wing,dendrite | third instar larval stageunspecified,axon | third instar larval stageunspecified,amnioserosa,embryonic dorsal epidermis,embryonic/larval dorsal trunk,NMJ bouton | third instar larval stage,NMJ bouton | adult stage,class IV dendritic arborizing neuron | third instar larval stage,endocytic vesicleunspecified,wing blade,posterior compartment,epithelium,female germline cyst,adult thorax,male genitalia,muscle tendon junctionMef2.PR,embryonic/larval neuromuscular junction,early endosomeCU1,wing hair,vesicleeg-Mz360,scutellar bristle,endosomeBx-MS1096,rhabdomereGMR.PF" DRSC00777 EK 0.807389352 -1.234961499 0.174691036 -5.995475044 0.209746363 -1.965172754 FBgn0034067 CG8399 http://flybase.net/reports/FBgn0034067.html FBgn0026300 protein_coding_gene 0000293=ferric-chelate reductase activity 0055114=oxidation-reduction process 0016021=integral component of membrane "SDR2, sdr2, stromal cell-derived receptor 2, anon-EST:ParkEST009" "IPR006593=Cytochrome b561/ferric reductase transmembrane, IPR005018=DOMON domain, IPR004877=Cytochrome b561 domain, IPR002861=Reeler domain" CG8399 16-Dec-15 2015_12 WBGene00007339(C05D12.1) "ENSXETG00000011666(FRRS1),ENSXETG00000013197()" ENSMUSG00000033386(Frrs1) ENSG00000156869(FRRS1) "viable,visible" trichogen cell FBgn0000568 Eip75B Ecdysone-induced protein 75B http://flybase.net/reports/FBgn0000568.html "FBgn0010914, FBgn0011342, FBgn0011386, FBgn0011430, FBgn0011438, FBgn0013628, FBgn0043377, FBgn0046398, FBgn0046399, FBgn0047288" protein_coding_gene "0004887=thyroid hormone receptor activity, 0020037=heme binding, 0003677=DNA binding, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding" "0007591=molting cycle, chitin-based cuticle, 0019730=antimicrobial humoral response, 0035075=response to ecdysone, 0048477=oogenesis, 0006355=regulation of transcription, DNA-templated, 0010468=regulation of gene expression, 0007553=regulation of ecdysteroid metabolic process, 0018990=ecdysis, chitin-based cuticle, 0043401=steroid hormone mediated signaling pathway" 0005634=nucleus "l(3)j5E1, l(3)neo25, Eip75A, anon-WO0172774.32, E75A, DmE75A, dE75, eip75B, NR1D3, E75-C, DmE75B, BcDNA:GM02640, E75C, anon-WO0172774.31, Ecdysone inducible protein 75B, l(3)j3A6, E75B, 57B, E75, ecdysone-induced protein 75, 75B, EP1121b, Eip75 A, l(3)j12E8, l(3)07041, Eip75, Mgn00274, E75 nuclear receptor, l(3)j11A6, CG8127, Rev-Erb" "IPR001728=Thyroid hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR001723=Nuclear hormone receptor, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG8127 16-Dec-15 2015_12 larval stage | late third instar larval stage embryonic/larval salivary gland

"developmental rate defective,large body,lethal,lethal - all die during pupal stage,viable,fertile,visible,recessive,partially lethal - majority die,lethal - all die before end of second instar larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority live,flightless,uncoordinated,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,long lived,starvation stress response defective,male limited" "wing,egg,germline clone,follicle cell,oocyte,germline cell,female,embryonic/larval midgut,midgut constriction 1,midgut chamber 3,mouth hooks,embryonic/larval anterior spiracle,eye" FBgn0004583 ex expanded http://flybase.net/reports/FBgn0004583.html "FBgn0000220, FBgn0000610, FBgn0002118, FBgn0010479, FBgn0021897" protein_coding_gene 0005515=protein binding "0035329=hippo signaling, 0008101=decapentaplegic signaling pathway, 0035331=negative regulation of hippo signaling, 0032456=endocytic recycling, 0042327=positive regulation of phosphorylation, 0042127=regulation of cell proliferation, 0007050=cell cycle arrest, 0001745=compound eye morphogenesis, 0046621=negative regulation of organ growth, 0007096=regulation of exit from mitosis, 0045892=negative regulation of transcription, DNA-templated, 0046620=regulation of organ growth, 0045595=regulation of cell differentiation, 0009966=regulation of signal transduction, 0007298=border follicle cell migration, 0007165=signal transduction, 0042981=regulation of apoptotic process, 0045571=negative regulation of imaginal disc growth, 0008285=negative regulation of cell proliferation, 0007444=imaginal disc development, 0040008=regulation of growth, 0001751=compound eye photoreceptor cell differentiation" "0016324=apical plasma membrane, 0005856=cytoskeleton, 0005915=zonula adherens" "CG4114, l(2)01270, l(2)ey, Ex, brl, braille, 1270, Expanded" "IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019748=FERM central domain, IPR018980=FERM, C-terminal PH-like domain, IPR029071=Ubiquitin-related domain, IPR000299=FERM domain, IPR019749=Band 4.1 domain" CG4114 16-Dec-15 2015_12 WBGene00001493(frm-7) larval stage imaginal disc

larval stage " dorsal mesothoracic disc

, imaginal disc

, ventral thoracic disc

" "lethal,recessive,visible,somatic clone,mitotic cell cycle defective,viable,increased cell number,cell non-autonomous,fertile,hyperplasia,cell migration defective,decreased cell size,partially lethal - majority die,planar polarity defective,cold sensitive,uncoordinated,decreased cell number,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell death,size defective" "eye,somatic clone,interommatidial bristle,supernumerary,ommatidium,cell autonomous,cell non-autonomous,retina,eye disc,eye-antennal disc,wing disc,photoreceptor cell,spermatogonial cyst,vibrissae,anterior scutellar bristle,wing,pigment cell,border follicle cell,leg,thorax,anterior crossvein,posterior crossvein,interommatidial bristle & eye disc & pupa,imaginal disc,wing vein,adult thorax,adult abdomen,antenna,postgenal sensillum,cold sensitive,adult head,embryonic/larval optic lobe,antennal sense organ,head,prothoracic tarsal segment 3,prothoracic tarsal segment 4,prothoracic tarsal segment 5,mesothoracic tarsal segment 3,mesothoracic tarsal segment 4,mesothoracic tarsal segment 5,metathoracic tarsal segment 3,metathoracic tarsal segment 4,metathoracic tarsal segment 5,arista,haltere disc,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc,embryonic/larval glial cell,ectopic,wing margin,anterior,eye photoreceptor cell,cone cell,inter-ommatidial cell | pupal stage,eye disc | third instar larval stage,morphogenetic furrow | third instar larval stage,1st posterior cell,mesothoracic tergum,inter-ommatidial cell,posterior" FBgn0069228 gl(2L)37-36 gl(2L)37-36 http://flybase.net/reports/FBgn0069228.html gene 0007379=segment specification 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0011746 ana anachronism http://flybase.net/reports/FBgn0011746.html protein_coding_gene 0008083=growth factor activity "0040007=growth, 0007406=negative regulation of neuroblast proliferation" 0005576=extracellular region "Anachronism, medullaless, med, CG8084" "IPR001111=Transforming growth factor-beta, N-terminal" CG8084 16-Dec-15 2015_12 " larval stage , embryonic stage | stage >13 " " optic lobe

, larval central nervous system | restricted

, glial cell

, larval brain

, embryonic central nervous system | restricted

, ventral nerve cord

" " embryonic stage | stage >13 , larval stage " " embryonic central nervous system | restricted

, larval central nervous system | restricted

, optic lobe

, larval brain

, ventral nerve cord

, glial cell

" "viable,smell perception defective,recessive,wild-type" "type I neuroblast,somatic clone,neuroblast,thoracic neuroblast,optic lobe & neuroblast" DRSC07579 E 0.886816569 -0.305318874 1.442945115 -1.723643439 0.76349373 0.1621361 FBgn0011655 Med Medea http://flybase.net/reports/FBgn0011655.html "FBgn0002479, FBgn0002509, FBgn0013946, FBgn0027760" protein_coding_gene "0030616=transforming growth factor beta receptor, common-partner cytoplasmic mediator activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005515=protein binding" "0045887=positive regulation of synaptic growth at neuromuscular junction, 0030509=BMP signaling pathway, 0009953=dorsal/ventral pattern formation, 0045705=negative regulation of salivary gland boundary specification, 0035019=somatic stem cell maintenance, 0008283=cell proliferation, 0048666=neuron development, 0007179=transforming growth factor beta receptor signaling pathway, 0007507=heart development, 0031290=retinal ganglion cell axon guidance, 0009950=dorsal/ventral axis specification, 0007476=imaginal disc-derived wing morphogenesis, 0030718=germ-line stem cell maintenance, 0007480=imaginal disc-derived leg morphogenesis, 0042078=germ-line stem cell division, 0006355=regulation of transcription, DNA-templated, 0030707=ovarian follicle cell development" "0005667=transcription factor complex, 0005634=nucleus, 0005737=cytoplasm" "SMAD4, CG1775, l(3)12m-137, MED, dSmad4, E(zen)3, med, l(3)XIIm137, lethal(3)SG36, lethal(3)SG70, Smad4, Media, medea, l(3)11m-254, l(3)SG70, l(3)SG36, anon-EST:Posey121" "IPR001132=SMAD domain, Dwarfin-type, IPR008984=SMAD/FHA domain, IPR013790=Dwarfin, IPR013019=MAD homology, MH1, IPR017855=SMAD domain-like, IPR003619=MAD homology 1, Dwarfin-type" CG1775 16-Dec-15 2015_12 "ENSDARG00000045094(si:dkey-222b8.1),ENSDARG00000070428(LOC100151181),ENSDARG00000069153,ENSDARG00000012649(LOC100333050),ENSDARG00000023527" WBGene00004858(sma-4) ENSXETG00000022355(SMAD4) " embryonic stage | stage 16 , embryonic stage | stage 14 , embryonic stage | stage 7 , embryonic stage | stage 4 , embryonic stage | >=stage 14 " " midgut constriction 2

, ectoderm

, mesoderm

,

anterior , endoderm

, embryonic central nervous system | restricted

" "visible,neuroanatomy defective,neurophysiology defective,small body,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,cell growth defective,somatic clone,viable,lethal - all die before end of embryonic stage,germline clone,rescuable maternal effect,some die during embryonic stage,maternal effect" "wing vein,ectopic,wing,leg,bouton,neuromuscular junction,neuromuscular junctionKpn-A),embryonic/larval somatic muscle,embryonic/larval central nervous system,imaginal disc,cell cycle,embryonic/first instar larval cuticle,denticle belt,larval head,eye,somatic clone,amnioserosa,lamina,eye photoreceptor cell stalk,gastric caecum,embryonic/larval midgut,midgut constriction 2,female germline stem cell,germarium,male germline stem cell,germline clone,follicle stem cell,follicle cell,crystal cell,synapse,t-bar,filzkorper,dorso-lateral,posterior crossvein,wing vein L4,dorsal cluster neuron,chorion | maternal effect | somatic clone,egg operculum,maternal effect,eye disc,fat body,wing disc,adult thorax,tibia,femur,tarsal segment 4,embryonic epidermis,pretarsus,ventral,cell non-autonomous,wing hinge,cell autonomous,wing margin,morphogenetic furrow" FBgn0000585 erratic erratic http://flybase.net/reports/FBgn0000585.html gene 0001700=embryonic development via the syncytial blastoderm "l(2)31El, err" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0262404 mir-996 mir-996 stem loop http://flybase.net/reports/FBgn0262404.html "FBgn0259157, FBgn0262240" miRNA_gene "dme-mir-996, miR-996, 996, miR996, CR42947" CR42947 16-Dec-15 2015_12 "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030711 Rrp47 http://flybase.net/reports/FBgn0030711.html protein_coding_gene 0010468=regulation of gene expression "lincRNA.1007, Rrp47, dRrp47, CG8928" "IPR007146=Sas10/Utp3/C1D, IPR011082=Exosome-associated factor Rrp47/DNA strand repair C1D" CG8928 16-Dec-15 2015_12 ENSDARG00000021112(c1d) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000543 ecd ecdysoneless http://flybase.net/reports/FBgn0000543.html FBgn0035324 protein_coding_gene 0070990=snRNP binding "0009608=response to symbiont, 0007443=Malpighian tubule morphogenesis, 0042810=pheromone metabolic process, 0008258=head involution, 0022008=neurogenesis, 0008362=chitin-based embryonic cuticle biosynthetic process, 1903220=positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity, 0002168=instar larval development, 0007030=Golgi organization, 0006697=ecdysone biosynthetic process, 0007281=germ cell development, 0048542=lymph gland development, 0007390=germ-band shortening, 0048477=oogenesis, 0016319=mushroom body development, 0000398=mRNA splicing, via spliceosome, 0002165=instar larval or pupal development, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0007591=molting cycle, chitin-based cuticle" 0005737=cytoplasm "l(3)ecd, ecd-1, Ed, ecdysone, CG5714, l(3)ecd-1, ecd1, echinoid, l(3)62Db, ecdl, Echinoid, l(3)ecd1" IPR010770=Ecd family CG5714 16-Dec-15 2015_12 ENSDARG00000022944(LOC100334770) ENSXETG00000023586(ECD) ENSMUSG00000021810(Ecd) ENSG00000122882(ECD) unfertilized egg stage egg

"increased cell death,visible,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,small body,immune response defective,heat sensitive,recessive,short lived,lethal,female sterile,temperature conditional,neuroanatomy defective,developmental rate defective,locomotor behavior defective,neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,germline clone,dominant,partially,maternal effect,viable" "wing disc,anterior crossvein,1st posterior cell,prothoracic gland,macrochaeta & adult thorax,embryonic/larval lymph gland,eye,heat sensitive,morphogenetic furrow,egg chamber,nurse cell,follicle cell,yolk,egg,blastoderm embryo,stomodeal invagination,amnioproctodeal invagination,extended germ band embryo,lamellocyte,hemocyte,eye-antennal disc,ventral thoracic disc,macrochaeta & adult thorax | conditional ts,larva,vitelline membrane,chorion,Golgi stack | heat sensitive,dorsal closure embryo,embryonic/first instar larval cuticle,border follicle cell,synapse | heat sensitive,NMJ bouton,embryonic/larval neuromuscular junction,embryonic/larval Malpighian tubule Type II cell,female germline cell,supernumerary,fusome | heat sensitive,lobe system of adult mushroom body,mushroom body beta-lobe,mouth hooks,germline clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0024836 stan starry night http://flybase.net/reports/FBgn0024836.html FBgn0026246 protein_coding_gene "0004872=receptor activity, 0005509=calcium ion binding, 0005057=receptor signaling protein activity, 0004888=transmembrane signaling receptor activity, 0004930=G-protein coupled receptor activity, 0050839=cell adhesion molecule binding" "0016358=dendrite development, 0048813=dendrite morphogenesis, 0090175=regulation of establishment of planar polarity, 0035159=regulation of tube length, open tracheal system, 0016055=Wnt signaling pathway, 0045773=positive regulation of axon extension, 0030177=positive regulation of Wnt signaling pathway, 0007409=axonogenesis, 0007464=R3/R4 cell fate commitment, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0016318=ommatidial rotation, 0007165=signal transduction, 0001738=morphogenesis of a polarized epithelium, 0048057=R3/R4 development, 0070593=dendrite self-avoidance, 0007411=axon guidance, 0007367=segment polarity determination, 0030178=negative regulation of Wnt signaling pathway, 0050770=regulation of axonogenesis, 0001736=establishment of planar polarity, 0016319=mushroom body development, 0051963=regulation of synapse assembly, 0007164=establishment of tissue polarity, 1902669=positive regulation of axon guidance, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0042067=establishment of ommatidial planar polarity, 0007186=G-protein coupled receptor signaling pathway, 0045746=negative regulation of Notch signaling pathway" "0005911=cell-cell junction, 0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "STAN, CG11895, fmi, fmi/stan, serpentine cadherin, Stan, Flamingo, Flam, flamingo, Fmi, Starry Night, starry Night, CT20776, Starry night" "IPR001879=GPCR, family 2, extracellular hormone receptor domain, IPR002049=Laminin EGF domain, IPR013032=EGF-like, conserved site, IPR017981=GPCR, family 2-like, IPR015919=Cadherin-like, IPR001881=EGF-like calcium-binding domain, IPR002126=Cadherin, IPR001791=Laminin G domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR000203=GPS motif, IPR000832=GPCR, family 2, secretin-like, IPR020894=Cadherin conserved site, IPR000742=EGF-like domain" CG11895 16-Dec-15 2015_12 "ENSDARG00000069185(celsr1a),ENSDARG00000058259,ENSDARG00000055825" WBGene00000398 "ENSXETG00000016189(CELSR3),ENSXETG00000023306(CELSR1)" "ENSMUSG00000016028(Celsr1),ENSMUSG00000068740(Celsr2),ENSMUSG00000023473(Celsr3)" "ENSG00000075275(CELSR1),ENSG00000143126(CELSR2),ENSG00000008300(CELSR3)" " embryonic stage--pupal stage , pupal stage " wing

" larval stage | third instar , pupal stage | early , pupal stage " " lamina & neuron

restricted , photoreceptor cell

, ovarian sheath cell

, medulla && neuron

" "partially lethal - majority die,neuroanatomy defective,planar polarity defective,viable,fertile,decreased cell number,somatic clone,recessive,cell autonomous,lethal,cell non-autonomous,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,cell polarity defective,body size defective,developmental rate defective,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,dominant" "dorsal multidendritic neuron ddaC,dendrite | third instar larval stage,photoreceptor cell R8,somatic clone,class IV dendritic arborizing neuron,wing hair,ommatidium,embryonic/larval mushroom body,adult mushroom body,calyx of adult mushroom body,photoreceptor cell R4,cell non-autonomous,dendrite | dorsal | embryonic stage,dorsal multidendritic neuron,dorsal multidendritic neuron ddaE,multidendritic neuron,neuromuscular junction | ectopic,wing,thorax,leg,adult thorax,precursor,wing cell,trichome & abdominal tergite,cell autonomous,embryonic/larval dorsal trunk,embryonic/larval neuron,dorsal wing blade,eye photoreceptor cell,longitudinal connective,2nd posterior cell & wing hair,macrochaeta,microchaeta & scutum,dorsocentral bristle,presumptive embryonic/larval peripheral nervous system,photoreceptor cell & axon,photoreceptor cell R8 & axon,photoreceptor cell R8 & axon & growth cone,photoreceptor cell R3,dendritic arborizing neuron,axon & photoreceptor cell R8 | somatic clone,trichome & pleural membrane | somatic clone,neuromuscular junction | ectopicstan2),neuromuscular junctionstan2),intersegmental nerve,microchaeta,trichome & adult abdomenptc-559.1,wing hair & 1st posterior cellptc-559.1,ectopic,sensory mother cell & spindleap-md52,vertical lobe of adult mushroom body,axon & photoreceptor cell R8 | somatic clone, standsRNA.extra.UAS,axon & photoreceptor cell R8 | somatic clone, standsRNA.intra.UAS,supernumerary" FBgn0004795 retn retained http://flybase.net/reports/FBgn0004795.html "FBgn0010517, FBgn0014151, FBgn0063144" protein_coding_gene "0000976=transcription regulatory region sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0070491=repressing transcription factor binding" "0045893=positive regulation of transcription, DNA-templated, 0048477=oogenesis, 0042063=gliogenesis, 0007435=salivary gland morphogenesis, 0048813=dendrite morphogenesis, 0007517=muscle organ development, 0009880=embryonic pattern specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045924=regulation of female receptivity, 0007431=salivary gland development, 0008049=male courtship behavior, 0007411=axon guidance, 0009952=anterior/posterior pattern specification" 0005634=nucleus "Retained, Dead ringer, unnamed, EHMT, 2535, DRI, Dead Ringer/Retain, retn/dri, Retn, Dri, EY2-10, CG5403, dri, dead-ringer, l(2)02535, dead ringer, BcDNA:LD35748" "IPR023334=REKLES domain, IPR001606=ARID DNA-binding domain" CG5403 16-Dec-15 2015_12 "ENSDARG00000067729(arid3a),ENSDARG00000070843,ENSDARG00000070474(arid3b)" WBGene00000476(cfi-1) "ENSXETG00000010647(ARID3B),ENSXETG00000021613(arid3a)" "ENSMUSG00000019564(Arid3a),ENSMUSG00000004661(Arid3b)" "ENSG00000116017(ARID3A),ENSG00000179361(ARID3B)" " embryonic stage | stage 15,16 , embryonic stage | stage 5-7 , embryonic stage | <2hr , embryonic stage | 3-5 hr , embryonic stage | 2-3hr " " anterior embryonic/larval midgut

, organism | 0-30% egg length

,

ubiquitous , labral segment

, pharyngeal muscle

, posterior embryonic/larval midgut

, organism | 70-100% egg length

, mesoderm

, embryonic/larval hindgut

,

40-60% egg length , embryonic/larval salivary gland duct

" " embryonic stage | 2-3hr , embryonic stage | stage 15,16 , embryonic stage , embryonic stage | 3-5 hr , embryonic stage | <2hr " "

0-25% egg length , amnioserosa

, embryonic salivary gland

,

75-100% egg length , mesoderm

, embryonic/larval foregut

, embryonic ventral nervous system | segmentally repeated

,

40-60% egg length ,

ubiquitous , ring gland

, embryonic brain | restricted

" "neuroanatomy defective,somatic clone,lethal,partially,courtship behavior defective,female,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,visible,female sterile,fertile,reduced,behavior defective,rescuable maternal effect,mitotic cell cycle defective,germline clone" "embryonic/larval somatic muscle,egg,germline clone,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,mushroom body beta-lobe,adult mushroom body,subesophageal ganglion,somatic clone,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,embryonic/larval hindgut,wing vein,sensillum campaniformium,wing sensillum,neuron,longitudinal connective,interface glial cell,syncytial blastoderm embryo,embryonic segment,extended germ band embryo,cephalopharyngeal skeleton,hypostomal sclerite,lateral process,somatic muscle,pharyngeal muscle,embryonic/larval pericardial cell,dorsal closure embryo,embryonic hindgut,embryonic/larval glial cell,axonMZ1580" FBgn0026623 ripp rippchen http://flybase.net/reports/FBgn0026623.html gene "0007391=dorsal closure, 0007494=midgut development, 0008258=head involution, 0007417=central nervous system development" rip 16-Dec-15 2015_12 "presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,glial cell,midline glial cell,ectopic" FBgn0026091 E(ltv)335 E(ltv)335 http://flybase.net/reports/FBgn0026091.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003170 pvt postverticalless http://flybase.net/reports/FBgn0003170.html gene 16-Dec-15 2015_12 "visible,male fertile,viable,female sterile" "wing,adult thorax & microchaeta,postvertical bristle,adult head,eye" FBgn0031604 Elp3 Elongator complex protein 3 http://flybase.net/reports/FBgn0031604.html protein_coding_gene "0008607=phosphorylase kinase regulator activity, 0016407=acetyltransferase activity, 0004402=histone acetyltransferase activity, 0051536=iron-sulfur cluster binding" "0006357=regulation of transcription from RNA polymerase II promoter, 2000289=regulation of photoreceptor cell axon guidance, 0018394=peptidyl-lysine acetylation, 0051124=synaptic growth at neuromuscular junction, 0016573=histone acetylation, 0007626=locomotory behavior, 0030431=sleep, 0048789=cytoskeletal matrix organization at active zone, 0002168=instar larval development, 0030097=hemopoiesis, 0050808=synapse organization" "0005634=nucleus, 0008023=transcription elongation factor complex, 0005737=cytoplasm, 0045202=synapse" "elp3, dmHAG408, elp-3, elongator protein 3, D-elp3, ELP3, CG15433, Dmel\ELP3, Elp3, Dmel/ELP3, Elongator protein 3, HAT, Elongator Protein 3" "IPR006638=Elongator protein 3/MiaB/NifB, IPR007197=Radical SAM, IPR023404=Radical SAM, alpha/beta horseshoe, IPR000182=GNAT domain, IPR005910=Histone acetyltransferase ELP3, IPR016181=Acyl-CoA N-acyltransferase" CG15433 16-Dec-15 2015_12 ENSDARG00000042005(elp3) YPL086C(ELP3) WBGene00014123(elpc-3) ENSXETG00000021151(elp3) ENSMUSG00000022031(Elp3) ENSG00000134014(ELP3) "lethal,neurophysiology defective,neuroanatomy defective,viable,visible,heat sensitive,hyperactive,partially lethal - majority die,some die during pupal stage,sleep defective" "presynaptic cytoskeletal matrix assembled at active zones,photoreceptor cell,trichogen cell,NMJ bouton,type I bouton" FBgn0015245 Hsp60 Heat shock protein 60 http://flybase.net/reports/FBgn0015245.html "FBgn0001483, FBgn0001749, FBgn0004659, FBgn0010375" protein_coding_gene "0051082=unfolded protein binding, 0005524=ATP binding" "0009408=response to heat, 0042026=protein refolding, 0034605=cellular response to heat, 0006626=protein targeting to mitochondrion, 0006457=protein folding, 0006458='de novo' protein folding, 0007005=mitochondrion organization" "0005743=mitochondrial inner membrane, 0005739=mitochondrion, 0005811=lipid particle, 0005759=mitochondrial matrix, 0005875=microtubule associated complex" "cpn60, heat shock protein 60 kDa, l(1)HM21, SSP 7506, 60-kDa heat shock protein, mitochondrial, Hsp60A, heat shock protein 60, l(1)10Ac, 12, DmHsp60, Hsp 60, hsp60, IEF16, l(1)L12, HSP60A, d-hsp60, lethal(1)10Ac, Mmp-P1, CG12101, l(1)dp025, BP5, HSP60, hsp60A, Dmhsp60, l(1)BP5, Mitochondrial matrix protein P1, Cpn60, G62, l(1)G8, HEAT SHOCK PROTEIN 60" "IPR001844=Chaperonin Cpn60, IPR027409=GroEL-like apical domain, IPR018370=Chaperonin Cpn60, conserved site, IPR002423=Chaperonin Cpn60/TCP-1 family, IPR027413=GroEL-like equatorial domain" CG12101 16-Dec-15 2015_12 ENSDARG00000056160(hspd1) YLR259C(HSP60) WBGene00002025(hsp-60) ENSXETG00000007509(HSPD1) ENSMUSG00000025980(Hspd1) ENSG00000144381(HSPD1) "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,wild-type,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,polyphasic,cell lethal,germline clone,cold sensitive" "tergite,blastoderm embryo" FBgn0050359 Mal-A5 Maltase A5 http://flybase.net/reports/FBgn0050359.html FBgn0033295 protein_coding_gene "0003824=catalytic activity, 0043169=cation binding" 0005975=carbohydrate metabolic process "mal_A5, Drome_A5, CG8689, CG30359" "IPR013781=Glycoside hydrolase, catalytic domain, IPR015902=Glycoside hydrolase, family 13, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR017853=Glycoside hydrolase superfamily" CG30359 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) viable FBgn0016031 lama lamina ancestor http://flybase.net/reports/FBgn0016031.html protein_coding_gene "0046843=dorsal appendage formation, 0002121=inter-male aggressive behavior, 0007444=imaginal disc development" 0005576=extracellular region CG10645 IPR007000=Phospholipase B-like CG10645 16-Dec-15 2015_12 "ENSDARG00000059366(zgc:158619),ENSDARG00000063313(plbd1)" "WBGene00021852(Y54F10AM.8),WBGene00008607(F09B12.3),WBGene00012544(Y37D8A.2)" ENSXETG00000017657(PLBD2) "ENSMUSG00000029598(Plbd2),ENSMUSG00000030214(Plbd1)" "ENSG00000151176(PLBD2),ENSG00000121316(PLBD1)" "behavior defective,recessive,learning defective,viable,fertile" "germline cell,male,dorsal appendage" DRSC11361 K 0.233100554 0.391387124 0.451408271 0.574265529 -1.841436218 0.602202598 FBgn0001417 l(1)6Da lethal (1) 6Da http://flybase.net/reports/FBgn0001417.html gene 16-Dec-15 2015_12 "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" female reproductive system FBgn0023440 grape Grape http://flybase.net/reports/FBgn0023440.html gene gra 16-Dec-15 2015_12 visible FBgn0060769 l(3)S062118b lethal (3) S062118b http://flybase.net/reports/FBgn0060769.html gene 0621/18 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0010399 Nmdar1 NMDA receptor 1 http://flybase.net/reports/FBgn0010399.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0004972=N-methyl-D-aspartate selective glutamate receptor activity" "0050975=sensory perception of touch, 0035235=ionotropic glutamate receptor signaling pathway, 0007616=long-term memory, 0072375=medium-term memory, 0006811=ion transport, 0042331=phototaxis, 0007476=imaginal disc-derived wing morphogenesis, 0008306=associative learning, 0008355=olfactory learning" "0016021=integral component of membrane, 0008328=ionotropic glutamate receptor complex" "Nmdar, NMDA, NMDAR1, dNR1, NMdar1, CG2902, dsNR1, NMDA receptor I, NMDAR, NR1, nmr, NMDA R1, DMNMDAR1, DrNR1, DmelNmdar1, NRI, NMDA receptor, DNMDAR-I, DNmdar, dnmdar-I" "IPR001320=Ionotropic glutamate receptor, IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region, IPR018882=Calmodulin-binding domain C0, NMDA receptor, NR1 subunit, IPR001508=Ionotropic glutamate receptor, metazoa, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG2902 16-Dec-15 2015_12 "ENSDARG00000027828(grin1a),ENSDARG00000025728(grin1b)" WBGene00003774(nmr-1) ENSXETG00000022933(GRIN1) ENSMUSG00000026959(Grin1) ENSG00000176884(GRIN1) "memory defective,heat sensitive,RU486 conditional,viable,recessive,learning defective,partially lethal - majority die,mating defective,dominant,phototaxis defective,neuroanatomy defective,touch sensitivity defective" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0261725 EC282 http://flybase.net/reports/FBgn0261725.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000009 Abnormal-abdomen Abnormal abdomen http://flybase.net/reports/FBgn0000009.html gene "Abnormal, A" 16-Dec-15 2015_12 "visible,semidominant,viable,female,female fertile" "tergite,cuticle,microchaeta & abdomen,macrochaeta & abdomen,sternite" FBgn0001064 Fs(3)Ros Female sterile (3) Rosd http://flybase.net/reports/FBgn0001064.html gene "Fs(3)Sz30, Fs(3)Rosd" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,maternal effect" FBgn0259572 B0016 http://flybase.net/reports/FBgn0259572.html gene 16-Dec-15 2015_12 visible wing FBgn0067756 l(1)G0073 lethal (1) G0073 http://flybase.net/reports/FBgn0067756.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0004680 fb fine bristle http://flybase.net/reports/FBgn0004680.html gene 16-Dec-15 2015_12 "visible,viable,fertile,recessive" "macrochaeta,wing" FBgn0001801 l(1)Mc23 lethal (1) Mc23 http://flybase.net/reports/FBgn0001801.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031629 Clect27 C-type lectin 27kD http://flybase.net/reports/FBgn0031629.html protein_coding_gene 0030246=carbohydrate binding CG3244 "IPR016186=C-type lectin-like, IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin, IPR016187=C-type lectin fold" CG3244 16-Dec-15 2015_12 "visible,lethal,viable,fertile" "wing,anterior crossvein" FBgn0066324 toi toi http://flybase.net/reports/FBgn0066324.html gene "0008355=olfactory learning, 0007611=learning or memory, 0007632=visual behavior, 0008542=visual learning" Toi 16-Dec-15 2015_12 "memory defective,visual behavior defective,recessive,learning defective,neurophysiology defective" FBgn0028577 pUf68 poly U binding factor 68kD http://flybase.net/reports/FBgn0028577.html FBgn0062032 protein_coding_gene "0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding, 0008266=poly(U) RNA binding" "0000380=alternative mRNA splicing, via spliceosome, 0022008=neurogenesis, 0051726=regulation of cell cycle, 0006376=mRNA splice site selection, 0001558=regulation of cell growth, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome, 0007282=cystoblast division" "0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0043234=protein complex, 0071011=precatalytic spliceosome" "CG12085, pUbsf, PUF60, half-pint, Half pint, anon-WO0118547.408, DPUF68, dFIR, HFP, Half-pint, half pint, PUF68, puf68, polyU binding splicing factor, Puf68, hfp, Puf60, Hfp, Fir, pUF68" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006532=Poly-U binding splicing factor, half-pint" CG12085 16-Dec-15 2015_12 "ENSDARG00000032175(puf60a),ENSDARG00000001241(puf60b)" WBGene00004389(rnp-6) ENSXETG00000012469(PUF60) ENSMUSG00000002524(Puf60) ENSG00000179950(PUF60) " embryonic stage | stage 1-4 , embryonic stage | stage 4-6 , adult stage | female " " organism

, ovary

" oogenesis stage ovary

"viable,developmental rate defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,large body,increased cell death,mitotic cell cycle defective,cytokinesis defective,lethal - all die before end of P-stage,some die during pharate adult stage,somatic clone,increased cell growth,male sterile,female sterile,fertile,neuroanatomy defective,visible,partially lethal - majority die" "melanotic mass,leg,wing,sex comb,scutellar bristle,wing disc,eye disc,mitosis & nuclear chromosome[-],actomyosin contractile ring[-],somatic clone | third instar larval stage,egg chamber,karyosome,nurse cell & nuclear chromosome,dorsal appendage,egg,nurse cell,ring canal,ovary,germline clone,eye,ommatidium,eye disc | larval stage,wing vein,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08731 EK -0.373983275 0.419950369 -1.802455968 0.71895447 2.597959698 1.819433007 FBgn0032704 Jwa Jwa ortholog http://flybase.net/reports/FBgn0032704.html protein_coding_gene 0045471=response to ethanol 0012505=endomembrane system "djwa, GH05842p, CG10373" IPR004895=Prenylated rab acceptor PRA1 CG10373 16-Dec-15 2015_12 "ENSDARG00000032535(praf2),ENSDARG00000016238(arl6ip5b),ENSDARG00000044192(arl6ip5a)" WBGene00017070(praf-3) ENSXETG00000025139(ARL6IP5) "ENSMUSG00000035199(Arl6ip5),ENSMUSG00000031149(Praf2)" "ENSG00000144746(ARL6IP5),ENSG00000102050" "chemical resistant,chemical sensitive,partially lethal - majority die,chemical conditional,viable" FBgn0015270 Orc2 Origin recognition complex subunit 2 http://flybase.net/reports/FBgn0015270.html "FBgn0001009, FBgn0002365" protein_coding_gene "0003682=chromatin binding, 0003677=DNA binding" "0006270=DNA replication initiation, 0006342=chromatin silencing, 0006260=DNA replication, 0030261=chromosome condensation, 0007052=mitotic spindle organization, 0006261=DNA-dependent DNA replication, 0007076=mitotic chromosome condensation, 0022008=neurogenesis, 0007307=eggshell chorion gene amplification, 0008283=cell proliferation" "0000792=heterochromatin, 0005664=nuclear origin of replication recognition complex, 0005723=alpha-heterochromatin, 0005634=nucleus" "ORC2, k43, l(3)A5, lethal(3)88Ab, DmORC2, CG3041, dOrc2, origin recognition complex 2, Orc-2, DmOrc2p, l(3)88Ab, DmORC 2, l(3)SG44, rDmORC, origin recognition complex, DmOrc2, fs(3)293, l(3)k43, ORC, Origin Recognition Complex subunit 2, orc2, l(3)K43, l(3)dsl5, Orc2p, fs(3)293-19" "IPR007220=Origin recognition complex, subunit 2" CG3041 16-Dec-15 2015_12 YBR060C(ORC2) WBGene00003882(orc-2) ENSXETG00000004151(ORC2L) ENSMUSG00000026037(Orc2l) ENSG00000115942(ORC2) embryonic stage && larval stage embryonic stage | 0-4hr "lethal,wild-type,lethal - all die before end of pupal stage,recessive,some die during pupal stage,suppressor of variegation,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,viable,female sterile,cold sensitive,neuroanatomy defective,visible" "polytene chromosome | larval stage,mitotic metaphase,mitosis & nuclear chromosome,nuclear chromosome,imaginal disc,mitotic cell cycle,chromosome, centromeric region,nuclear chromosome | larval stage,chromatin | larval stage,follicle cell,spindle,cell cycle,mitotic metaphase293ë_7),mitosis & nuclear chromosome293ë_7),chorion,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,wing" FBgn0004622 TkR99D Tachykinin-like receptor at 99D http://flybase.net/reports/FBgn0004622.html "FBgn0011021, FBgn0044356, FBgn0044366" protein_coding_gene "0008188=neuropeptide receptor activity, 0004995=tachykinin receptor activity" "0007218=neuropeptide signaling pathway, 0050805=negative regulation of synaptic transmission, 0007217=tachykinin receptor signaling pathway, 0042048=olfactory behavior, 0007186=G-protein coupled receptor signaling pathway, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0016021=integral component of membrane, 0005886=plasma membrane, 0005887=integral component of plasma membrane" "TAKR99D, Takr99D, anon-WO0131005.11, dtkr, l(3)s2222, tachykinin receptor, Tachykinin receptor, Drosophila tachykinin receptor, CG7887, DmTRPR, TLR2_DROME, DTKR, Tak-r, DTK receptor, anon-WO0131005.9, Dtkr, TKR99D" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR001681=Neurokinin receptor" CG7887 16-Dec-15 2015_12 "ENSDARG00000043918(LOC100333270),ENSDARG00000003054(LOC559201),ENSDARG00000035533(LOC100003539),ENSDARG00000016025(LOC564017)" WBGene00016761(C49A9.7) ENSXETG00000008524(TACR1) "ENSMUSG00000028172(Tacr3),ENSMUSG00000030043(Tacr1),ENSMUSG00000020081(Tacr2)" "ENSG00000169836(TACR3),ENSG00000115353(TACR1),ENSG00000075073(TACR2)" " embryonic stage--pupal stage , adult stage , embryonic stage | stage >=14 " " subesophageal ganglion

, adult brain cortex

, embryonic neuron

, adult head

, neuron &&of adult nervous system

, central nervous system

, embryonic brain

, embryonic ventral nervous system | restricted

" "smell perception defective,neurophysiology defective,viable,fertile" "synaptic vesicleOrco.2.642.THsimVP22,antennal lobe glomerulus DM1,chemical conditional,antennal lobe glomerulus DM5,antennal lobe glomerulus DM2,antennal lobe glomerulus VM2" FBgn0015754 Lis-1 Lissencephaly-1 http://flybase.net/reports/FBgn0015754.html FBgn0021892 protein_coding_gene "0030234=enzyme regulator activity, 0045502=dynein binding, 0042623=ATPase activity, coupled" "0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 2001019=positive regulation of retrograde axon cargo transport, 0048814=regulation of dendrite morphogenesis, 0030381=chorion-containing eggshell pattern formation, 0051642=centrosome localization, 0007018=microtubule-based movement, 0072499=photoreceptor cell axon guidance, 0006886=intracellular protein transport, 0051225=spindle assembly, 0030473=nuclear migration along microtubule, 0051647=nucleus localization, 0048813=dendrite morphogenesis, 0046716=muscle cell cellular homeostasis, 0050790=regulation of catalytic activity, 0010970=microtubule-based transport, 0008298=intracellular mRNA localization, 0051299=centrosome separation, 0007093=mitotic cell cycle checkpoint, 0030510=regulation of BMP signaling pathway, 0042052=rhabdomere development, 0030716=oocyte fate determination, 0007283=spermatogenesis, 0007298=border follicle cell migration, 0045478=fusome organization, 0007294=germarium-derived oocyte fate determination, 0030706=germarium-derived oocyte differentiation, 0007303=cytoplasmic transport, nurse cell to oocyte, 0008104=protein localization, 0051383=kinetochore organization, 0048135=female germ-line cyst formation, 0034501=protein localization to kinetochore, 0016319=mushroom body development, 0048477=oogenesis, 0008088=axon cargo transport, 0019827=stem cell maintenance, 0007405=neuroblast proliferation" "0005828=kinetochore microtubule, 0030426=growth cone, 0030424=axon, 0005938=cell cortex, 0030425=dendrite, 0005813=centrosome, 0043025=neuronal cell body, 0031616=spindle pole centrosome, 0030286=dynein complex, 0000922=spindle pole, 0000776=kinetochore, 0005869=dynactin complex" "platelet-activating factor acetylhydrolase Ib beta-subunit homolog, lis1, DmLIS1, lissencephaly-1, DLis-1, DLis1, DLIS1, dLis1, Dlis-1, l(2)k13209, lis-1, D-Lis1, Lis1, LIS-1, CG8440, l(2R)W8, Lis 1, Paf-AHbeta, Dlis1, DLIS-1, n(2)k11702" "IPR001680=WD40 repeat, IPR006594=LIS1 homology motif, IPR017252=Dynein regulator LIS1, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG8440 16-Dec-15 2015_12 "ENSDARG00000026595(pafah1b1b),ENSDARG00000032013(pafah1b1a)" WBGene00003047(lis-1) ENSXETG00000019410(pafah1b1) ENSMUSG00000020745(Pafah1b1) ENSG00000007168(PAFAH1B1) " embryonic stage | early , adult stage && oogenesis stage | stage S4-7 , embryonic stage -- adult stage , adult stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10 " " oocyte

, ovary

, germarium | restricted

, nurse cell

" " embryonic stage -- adult stage , adult stage " ovary

"lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,sterile,male sterile,viable,fertile,female sterile,wild-type,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage" "photoreceptor cell & nucleus,dorsal appendage,spindle,cyst progenitor cell,spindle pole centrosome,spermatocyte,centrosome,spermatid,investment cone,Nebenkern,oocyte,oocyte nucleus,microtubule,egg chamber,nurse cell,supernumerary,microtubule organizing centerJp8),border follicle cell,somatic clone,egg,germline clone,nurse cell fusome,embryonic/larval mushroom body,adult mushroom body,dendrite | somatic clone,dendrite & abdominal dorsal multidendritic neuron ddaC | somatic clone,class IV dendritic arborizing neuron,germline stem cell,spindle | germline clone,cystoblast,germarium,germ band,embryonic/larval brain,centrosome & spermatocyte" FBgn0016047 nompA no mechanoreceptor potential A http://flybase.net/reports/FBgn0016047.html FBgn0033617 protein_coding_gene "0007605=sensory perception of sound, 0050954=sensory perception of mechanical stimulus, 0048813=dendrite morphogenesis" "0031012=extracellular matrix, 0005576=extracellular region" "nomp, Nomp-A, NompA, NOMPA, CG13207" "IPR001507=Zona pellucida domain, IPR003609=PAN/Apple domain" CG13207 16-Dec-15 2015_12 WBGene00016422(noah-1) "wild-type,auditory perception defective,locomotor behavior defective,recessive,uncoordinated,behavior defective,viable" "mechanosensory sensory organ,external sensory organ,eo neuron,sensillum campaniformium & wing vein L3 & adult,dendritic cap cell,Johnston's organ & scolopidium,Johnston's organ & dendritic cap cell,wing,leg,macrochaeta,adult antennal nerve,arista" FBgn0037131 CG14564 http://flybase.net/reports/FBgn0037131.html protein_coding_gene CG14564 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0001391 l(1)2Cc lethal (1) 2Cc http://flybase.net/reports/FBgn0001391.html gene l(1)VE651 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,polyphasic" "ovariole,germline clone,nurse cell,ovary" FBgn0001276 ix intersex http://flybase.net/reports/FBgn0001276.html FBgn0033625 protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0008134=transcription factor binding" "0060548=negative regulation of cell death, 0006357=regulation of transcription from RNA polymerase II promoter, 0019101=female somatic sex determination, 0048804=imaginal disc-derived female genitalia morphogenesis, 0007548=sex differentiation, 0007530=sex determination, 0035263=genital disc sexually dimorphic development, 0018993=somatic sex determination" 0016592=mediator complex "Intersex, Mediator complex subunit 29, CG13201, MED29" "IPR021018=Mediator complex, subunit Med29, metazoa" CG13201 16-Dec-15 2015_12 ENSDARG00000026448(med29) ENSXETG00000027298(MED29) ENSMUSG00000003444(Med29) ENSG00000063322(MED29) "visible,heat sensitive,semi-sterile,recessive,sex-determination defective,lethal,female sterile,male semi-sterile,female,male,courtship behavior defective,viable" "anal plate,ectopic,male terminalia,female terminalia,sex comb,female genitalia,male genitalia,tergite,sternite,abdominal tergite 6,female,gonopod long bristle,prothoracic metatarsal segment transverse row bristle,genital arch,lateral plate,penis,female genital disc,male genital disc primordium,heat sensitive,testis,spermatozoon,leg,male" DRSC06325 K -1.210506272 0.094251509 -0.164227534 0.445319919 1.742714767 1.999702295 FBgn0031424 VGlut Vesicular glutamate transporter http://flybase.net/reports/FBgn0031424.html protein_coding_gene "0005313=L-glutamate transmembrane transporter activity, 0005326=neurotransmitter transporter activity, 0005316=high-affinity inorganic phosphate:sodium symporter activity" "0035249=synaptic transmission, glutamatergic, 0055085=transmembrane transport, 0016057=regulation of membrane potential in photoreceptor cell, 0015813=L-glutamate transport" "0031982=vesicle, 0030285=integral component of synaptic vesicle membrane, 0016021=integral component of membrane, 0008021=synaptic vesicle" "DVGLUT, Vglut, MFS11, dvGlut, DV-Glut, dVGlut, vGluT, DVGluT, vGLUT, DVGlut, vGlut, Drosophila vesicular glutamate transporter, DvGluT, VGluT, vglut, dvglut, dvGluT, vesicular glutamate transporter, DvGlut, VGLUT, dVGLUT, CG9887" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG9887 16-Dec-15 2015_12 "ENSDARG00000036150,ENSDARG00000041150(slc17a6b),ENSDARG00000001127(slc17a6a),ENSDARG00000016480(slc17a7),ENSDARG00000057538,ENSDARG00000057728(slc17a8)" "YGR260W(TNA1),YIL166C()" WBGene00001135(eat-4) "ENSXETG00000008393(SLC17A6),ENSXETG00000003399(SLC17A7)" "ENSMUSG00000070570(Slc17a7),ENSMUSG00000030500(Slc17a6),ENSMUSG00000019935(Slc17a8)" "ENSG00000104888(SLC17A7),ENSG00000091664(SLC17A6),ENSG00000179520(SLC17A8)" "viable,neurophysiology defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,courtship behavior defective,male,lethal,flightless,uncoordinated,gravitaxis defective,female semi-sterile,fertile,phototaxis defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,synaptic vesicleBG380,neuromuscular junction,synaptic vesicle,neuropil,antennal lobe,synaptic vesicleVGlut2)" FBgn0026722 drosha drosha http://flybase.net/reports/FBgn0026722.html protein_coding_gene "0004525=ribonuclease III activity, 0003723=RNA binding, 0003725=double-stranded RNA binding" "0009267=cellular response to starvation, 0016319=mushroom body development, 0035070=salivary gland histolysis, 0030727=germarium-derived female germ-line cyst formation, 0031053=primary miRNA processing, 0022008=neurogenesis, 0007294=germarium-derived oocyte fate determination, 0016075=rRNA catabolic process" 0005634=nucleus "DROSHA, CG8730, Drosha" "IPR011907=Ribonuclease III, IPR000999=Ribonuclease III domain, IPR014720=Double-stranded RNA-binding domain" CG8730 16-Dec-15 2015_12 ENSDARG00000055563(rnasen) WBGene00009163(drsh-1) ENSMUSG00000022191(Rnasen) ENSG00000113360(DROSHA) "lethal,majority die during prepupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,somatic clone,neuroanatomy defective,majority die during larval stage,recessive,visible,viable" "imaginal disc,eye disc,mushroom body,somatic clone,alpha/beta Kenyon cell,alpha'/beta' Kenyon cell,gamma Kenyon cell,adult antennal lobe projection neuron adPN,oocyte,germline clone,embryonic/larval central nervous system,mushroom body gamma-lobe,adult antennal lobe projection neuron DL1 adPN,eye,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" DRSC07607 K -0.404120021 0.69733676 -0.479870126 1.08626846 3.117829275 0.943331097 FBgn0010078 RpL23 Ribosomal protein L23 http://flybase.net/reports/FBgn0010078.html protein_coding_gene "0017022=myosin binding, 0003735=structural constituent of ribosome" "0007052=mitotic spindle organization, 0022008=neurogenesis, 0000022=mitotic spindle elongation, 0006412=translation" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "ribosomal protein L23, TA01212p, RL17, Ribosomal protein L17A, L23, RpL17A, rpl23, CG3661, RPL17A, L17, Rpl17A" "IPR023571=Ribosomal protein L14 domain, IPR000218=Ribosomal protein L14b/L23e, IPR019972=Ribosomal protein L14 conserved site" CG3661 16-Dec-15 2015_12 ENSDARG00000053457(rpl23) "YER117W(RPL23B),YBL087C(RPL23A)" WBGene00004435(rpl-23) ENSXETG00000023719(rpl23) ENSMUSG00000071415(Rpl23) ENSG00000125691(RPL23) embryonic stage -- adult stage "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC04648 IEK -1.925582823 -1.865109659 -1.952796805 -5.500934793 1.243973576 2.38477189 FBgn0051482 CG31482 http://flybase.net/reports/FBgn0051482.html FBgn0037457 protein_coding_gene 0005576=extracellular region CG2337 "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG31482 16-Dec-15 2015_12 ENSDARG00000016837(glipr2l) WBGene00008604(F09B9.5) ENSMUSG00000028480(Glipr2) ENSG00000122694(GLIPR2) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12582 EK 0.168624687 -0.060099751 1.856435593 0.428152346 2.047727519 0.90411248 FBgn0024944 Oamb Octopamine receptor in mushroom bodies http://flybase.net/reports/FBgn0024944.html FBgn0040576 protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0004989=octopamine receptor activity" "0008049=male courtship behavior, 0030728=ovulation, 0060278=regulation of ovulation, 0006874=cellular calcium ion homeostasis, 0007211=octopamine or tyramine signaling pathway, 0007612=learning, 0051482=positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway" "0005886=plasma membrane, 0016021=integral component of membrane, 0005887=integral component of plasma membrane" "octopamine receptor OAMB, OAMB-1a, Dmoa1, Dm-OAMB, OAMB-AS, octopamine mushroom body receptor, octopamine-activated G-protein-coupled receptor, OctR, OAMB, OctR1, DmOCT1B, Oamb a, CG15698, DmOctalpha1Rb, octopamine receptor, DmOAMB, CG3856, GPCR, Oamb b, OAMB-K3, oamb" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG3856 16-Dec-15 2015_12 "ENSDARG00000024101(LOC568614),ENSDARG00000028725(LOC798498)" WBGene00004778(ser-3) "ENSXETG00000010368(ADRA1D),ENSXETG00000022213(ADRA1B)" "ENSMUSG00000045875(Adra1a),ENSMUSG00000050541(Adra1b)" "ENSG00000170214(ADRA1B),ENSG00000120907(ADRA1A)" " adult stage , adult stage | female " " mushroom body

, adult head

, oviduct | restricted

" "female semi-sterile,recessive,courtship behavior defective,male,learning defective,viable,female sterile,sleep defective,female fertile,memory defective" "oviduct,uterus,ovariole" DRSC15120 E -0.378260395 0.242586236 1.843658388 0.658452024 -0.446755209 0.010954094 FBgn0003416 sl small wing http://flybase.net/reports/FBgn0003416.html FBgn0011825 protein_coding_gene "0004435=phosphatidylinositol phospholipase C activity, 0004871=signal transducer activity" "0009395=phospholipid catabolic process, 0032868=response to insulin, 0045596=negative regulation of cell differentiation, 0007298=border follicle cell migration, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0030307=positive regulation of cell growth, 0035556=intracellular signal transduction" "PLCgammaDmel, PLC-gamma D, PLC&ygr;, PLC-gammaD, Phospholipase C gamma, CG4200, PLCgamma1, p145, PLC, plc-gammad, phospholipase Cgamma, phospholipase C gamma, PLCgamma, plc-gamma, PLC-gamma, DPLCgamma, Plcgamma, Small wing" "IPR001452=SH3 domain, IPR000008=C2 domain, IPR016279=Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma, IPR001192=Phosphoinositide phospholipase C family, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR000980=SH2 domain, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR011992=EF-hand domain pair, IPR015359=Phosphoinositide-specific phospholipase C, EF-hand-like domain, IPR001711=Phospholipase C, phosphatidylinositol-specific, Y domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG4200 16-Dec-15 2015_12 "ENSDARG00000017411,ENSDARG00000038442" YPL268W(PLC1) WBGene00004038(plc-3) "ENSXETG00000003578(PLCG2),ENSXETG00000019423(PLCG1)" "ENSMUSG00000016933(Plcg1),ENSMUSG00000034330(Plcg2)" "ENSG00000124181(PLCG1),ENSG00000197943(PLCG2)" " embryonic stage , embryonic stage -- adult stage " " anterior midgut proper primordium

, endoderm

, posterior midgut proper primordium

" "visible,viable,fertile,recessive,planar polarity defective,increased cell number,size defective,decreased cell size,somatic clone,dominant,lethal" "wing,ommatidium,photoreceptor cell R7,eye,wing vein,ectopic,interommatidial bristle,eye photoreceptor cell,cone cell,primary pigment cell,supernumerary,wing blade,primary segmental branch,rhabdomere | adult stage | somatic clone,somatic clone" DRSC20377 I 1.606927127 1.194586477 -0.428440558 0.719180748 0.757135179 -1.033673659 FBgn0053113 Rtnl1 Reticulon-like1 http://flybase.net/reports/FBgn0053113.html "FBgn0031666, FBgn0031667" protein_coding_gene "0042048=olfactory behavior, 0007029=endoplasmic reticulum organization, 0002121=inter-male aggressive behavior" "0030424=axon, 0005790=smooth endoplasmic reticulum, 0005783=endoplasmic reticulum, 0045169=fusome, 0005811=lipid particle, 0005737=cytoplasm, 0005829=cytosol, 0012505=endomembrane system" "Rtnl1, CG8895, G9, Reticulon, reticulon-like 1, reticulon-like1, CG33113, Reticulon-like1, Rtnl-1, Reticulon-like 1, rtnl1, CG18623, Retl1, reticulon, 142893_at" IPR003388=Reticulon CG33113 16-Dec-15 2015_12 "ENSDARG00000006497(rtn1a),ENSDARG00000021143(rtn1b)" ENSMUSG00000021087(Rtn1) ENSG00000115310(RTN4) "smell perception defective,viable,behavior defective,recessive,fertile,learning defective,short lived,heat sensitive" "embryonic/larval hemocyte | third instar larval stage,wing,posterior compartment" DRSC00851 K 0.390863167 -0.63775802 -0.140181985 0.475994984 -0.224553958 1.882254429 FBgn0031062 CG14230 http://flybase.net/reports/FBgn0031062.html FBgn0019898 protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003676=nucleic acid binding" 0022008=neurogenesis "anon-18DEe, cg14230, Nol8, unnamed, clone 9.42" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG14230 16-Dec-15 2015_12 ENSXETG00000020913(NOL8) ENSMUSG00000021392(Nol8) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC19586 IE 2.595735414 1.758411778 1.555101871 1.043312794 -1.371202873 1.068996085 FBgn0023172 RhoGEF2 Rho guanine nucleotide exchange factor 2 http://flybase.net/reports/FBgn0023172.html "FBgn0010569, FBgn0020519" protein_coding_gene "0019992=diacylglycerol binding, 0005089=Rho guanyl-nucleotide exchange factor activity" "0016476=regulation of embryonic cell shape, 0038032=termination of G-protein coupled receptor signaling pathway, 0035025=positive regulation of Rho protein signal transduction, 0007377=germ-band extension, 0070252=actin-mediated cell contraction, 0050770=regulation of axonogenesis, 0008360=regulation of cell shape, 0007369=gastrulation, 0007277=pole cell development, 0007370=ventral furrow formation, 0007375=anterior midgut invagination, 0035277=spiracle morphogenesis, open tracheal system, 0016331=morphogenesis of embryonic epithelium, 0031532=actin cytoskeleton reorganization, 0007374=posterior midgut invagination, 0007349=cellularization, 0007015=actin filament organization, 0090254=cell elongation involved in imaginal disc-derived wing morphogenesis, 0030589=pseudocleavage involved in syncytial blastoderm formation" "0045178=basal part of cell, 0016324=apical plasma membrane, 0045177=apical part of cell, 0005826=actomyosin contractile ring, 0030478=actin cap, 0045179=apical cortex, 0016328=lateral plasma membrane" "T2, rhogef2, unnamed, dRhoGEF, guanine nucleotide exchange factor 2, DRhoGEF2, Shar pei, akkordion, shar pei, CG9635, shar, Transcription unit 2, l(2)04291, RhoGEF2, Rho-GEF2, dRhoGEF2, RhoGF2, DRhoGEF, DrhoGEF2, Gef2, RG2, RhoGef2, Su(Rho1)2B, RhoGEF, rhoGEF2" "IPR015212=Regulator of G protein signalling-like domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR015721=Rho GTP exchange factor, IPR001849=Pleckstrin homology domain, IPR016137=RGS domain, IPR000219=Dbl homology (DH) domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001478=PDZ domain" CG9635 16-Dec-15 2015_12 WBGene00006468(rhgf-1) "ENSXETG00000023808(ARHGEF11),ENSXETG00000017018(ARHGEF12)" "ENSMUSG00000059495(Arhgef12),ENSMUSG00000041977(Arhgef11),ENSMUSG00000040940(Arhgef1)" "ENSG00000196914(ARHGEF12),ENSG00000132694(ARHGEF11),ENSG00000076928(ARHGEF1)" embryonic stage | stage <9 organism

"lethal,partially,visible,recessive,rescuable maternal effect,mitotic cell cycle defective,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,cell shape defective,conditional,female sterile,germline clone" "actin filament & embryonic/larval tracheal systembtl.PS,wing,wing disc,embryonic ventral epidermis,rescuable maternal effect,embryonic/first instar larval cuticle,germline clone,maternal effect,ventral,extended germ band embryo,anterior midgut primordium,posterior midgut primordium,blastoderm embryo,pole cell,actin cytoskeleton | blastoderm stage | germline clone,nucleus | blastoderm stage | germline clone,furrow canal,pole cell & cytoskeleton | germ-line clone,ventral midline,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,posterior spiracle primordium,embryonic/larval hemocyte | third instar larval stage,conditional | third instar larval stage,presumptive embryonic salivary gland,somatic clone,epithelial cell,amnioproctodeal invagination,mesectoderm,ventral furrow,stage 5 embryo,stomodeal invagination,mesoderm anlage" DRSC29373 K -0.112535073 -0.320274153 -0.995043335 -0.577791948 0.836836252 1.547629849 FBgn0042641 frc fringe connection http://flybase.net/reports/FBgn0042641.html "FBgn0010706, FBgn0010784, FBgn0011338, FBgn0024567, FBgn0028107, FBgn0036721, FBgn0046363, FBgn0046381" protein_coding_gene "0015165=pyrimidine nucleotide-sugar transmembrane transporter activity, 0005461=UDP-glucuronic acid transmembrane transporter activity, 0005460=UDP-glucose transmembrane transporter activity, 0005462=UDP-N-acetylglucosamine transmembrane transporter activity, 0005464=UDP-xylose transmembrane transporter activity, 0015297=antiporter activity, 0005458=GDP-mannose transmembrane transporter activity, 0005459=UDP-galactose transmembrane transporter activity, 0005457=GDP-fucose transmembrane transporter activity" "0007220=Notch receptor processing, 0015781=pyrimidine nucleotide-sugar transport, 0007447=imaginal disc pattern formation, 0007476=imaginal disc-derived wing morphogenesis, 0015787=UDP-glucuronic acid transport, 0015785=UDP-galactose transport, 0015788=UDP-N-acetylglucosamine transport, 0015786=UDP-glucose transport, 0015790=UDP-xylose transport, 0009880=embryonic pattern specification, 0001745=compound eye morphogenesis, 0007423=sensory organ development, 0007367=segment polarity determination" "0005797=Golgi medial cisterna, 0005794=Golgi apparatus" "UST74C, FRC, l(3)j2E3, ust74C, anon-WO0172774.5, frc, l(3)S070006, UDP-sugar transporter in 74C, l(3)10098, dFRC, anon-WO0172774.7, l(3)L6750, CG3874, Fringe-connection, Fringe connection, l(3)00073, UDP-GlcNAc/UDP-GlcUA, Frc, l(3)02619" IPR004853=Sugar phosphate transporter domain CG3874 16-Dec-15 2015_12 "ENSDARG00000011973(slc35d1a),ENSDARG00000027986(slc35d1b)" "YGL225W(VRG4),YER039C(HVG1)" WBGene00005025(sqv-7) ENSXETG00000012400(SLC35D1) ENSMUSG00000028521(Slc35d1) ENSG00000116704(SLC35D1) "cell polarity defective,lethal,visible,somatic clone,recessive,rescuable maternal effect,segment polarity phenotype,partially,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during second instar larval stage,some die during pupal stage,viable" "wing margin,ectopic,somatic clone,eye,ommatidium,wing vein,macrochaeta,anterior scutellar bristle,anterior postalar bristle,posterior postalar bristle,embryonic/first instar larval cuticle,embryonic segment,mesoderm,germline clone,cuticle,denticle belt,wing,anterior,wing margin bristle,joint,leg,eye photoreceptor cell,presumptive embryonic/larval nervous system,antenna" FBgn0004638 drk downstream of receptor kinase http://flybase.net/reports/FBgn0004638.html FBgn0021869 protein_coding_gene "0005515=protein binding, 0005118=sevenless binding, 0005070=SH3/SH2 adaptor activity" "0038202=TORC1 signaling, 0008355=olfactory learning, 0007614=short-term memory, 0007265=Ras protein signal transduction, 0001700=embryonic development via the syncytial blastoderm, 0045678=positive regulation of R7 cell differentiation, 0008595=anterior/posterior axis specification, embryo, 0008293=torso signaling pathway, 0007613=memory, 0007476=imaginal disc-derived wing morphogenesis, 0007015=actin filament organization, 0008306=associative learning, 0008360=regulation of cell shape, 0043410=positive regulation of MAPK cascade, 0045500=sevenless signaling pathway, 0007175=negative regulation of epidermal growth factor-activated receptor activity" "0005737=cytoplasm, 0005886=plasma membrane, 0005654=nucleoplasm" "Grb-2, Grb2/drk, Downstream of receptor kinase, Grb/drk, crkl, Drk, l(2)10626, 24/1, downstream of receptor kinases, Grb2, GRB2, P1112, downstream receptor kinase, Su(sev)R1, l(2)k13809, Drk/Grb2, CG6033, Enhancer of sevenless-2B, downstream of receptor kinase, E(sev)2B, DRK" "IPR001452=SH3 domain, IPR000980=SH2 domain" CG6033 16-Dec-15 2015_12 "ENSDARG00000038059(grb2),ENSDARG00000014709(zgc:103549)" WBGene00004774(sem-5) ENSXETG00000012520(grb2) ENSMUSG00000059923(Grb2) ENSG00000177885(GRB2) " embryonic stage , larval stage | third instar " " eye-antennal disc

, imaginal disc

" " larval stage | third instar , adult stage , pupal stage " " eye-antennal disc

, photoreceptor cell | presumptive

" "visible,dominant,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,fully,rescuable maternal effect,learning defective,neuroanatomy defective,memory defective" "wing,wing vein,ectopic,posterior,imaginal disc,embryonic/first instar larval cuticle,head,abdomen,intersegmental nerve,anterior fascicle & synapse | supernumerary,macrochaeta,dorsal air sac primordium,somatic clone,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,photoreceptor cell R7" DRSC07606 IEK -1.843913625 -4.651346134 -2.640024829 -0.42432868 -1.101126595 -3.522966956 FBgn0000615 exu exuperantia http://flybase.net/reports/FBgn0000615.html protein_coding_gene "0007317=regulation of pole plasm oskar mRNA localization, 0045451=pole plasm oskar mRNA localization, 0001700=embryonic development via the syncytial blastoderm, 0045450=bicoid mRNA localization, 0008595=anterior/posterior axis specification, embryo, 0007300=ovarian nurse cell to oocyte transport, 0007283=spermatogenesis, 0000398=mRNA splicing, via spliceosome, 0046331=lateral inhibition, 0008359=regulation of bicoid mRNA localization" "0000932=cytoplasmic mRNA processing body, 0071011=precatalytic spliceosome, 0005737=cytoplasm" "bs30h09.y1, exu1, Exuperantia, CG8994, Exu" CG8994 16-Dec-15 2015_12 " pupal stage , adult stage && oogenesis stage , adult stage | female , adult stage | male , larval stage | late , embryonic stage | early " " germarium

, oocyte

, nurse cell

" " adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage | stage S7-8 , adult stage && oogenesis stage , spermatogenesis && adult stage " " centripetally migrating follicle cell

, oocyte

, nurse cell

, testis

" "lethal,maternal effect,male sterile,female sterile,viable,fertile,visible,partially lethal - majority die,wild-type,long lived,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,female fertile" "tarsal segment,wing vein,labrum,embryonic head,anterior,embryonic labral segment,embryonic antennal segment,embryonic maxillary segment,embryonic thorax,prothoracic ventral denticle belt,embryonic abdomen,posterior,embryo,embryonic/first instar larval cuticle,cephalic furrow,maternal effect,chaeta,supernumerary" DRSC07615 EK -0.272565888 0.306883623 1.780965503 0.238000339 1.713752638 -0.286602726 FBgn0023518 trr trithorax-related http://flybase.net/reports/FBgn0023518.html FBgn0019895 protein_coding_gene "0042054=histone methyltransferase activity, 0005102=receptor binding, 0008270=zinc ion binding, 0003713=transcription coactivator activity, 0003677=DNA binding, 0042800=histone methyltransferase activity (H3-K4 specific)" "0051568=histone H3-K4 methylation, 0035332=positive regulation of hippo signaling, 0016571=histone methylation, 0007224=smoothened signaling pathway, 0048749=compound eye development, 1900114=positive regulation of histone H3-K9 trimethylation, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0045893=positive regulation of transcription, DNA-templated" "0005634=nucleus, 0005700=polytene chromosome, 0044666=MLL3/4 complex" "Trithorax-related, TRR, anon-2Bb, Trr, unnamed, trithorax related, CG3848, trithorax-related protein, EG:63B12.3" "IPR003889=FY-rich, C-terminal, IPR001214=SET domain, IPR015722=Histone-lysine N-methyltransferase Trr, IPR003888=FY-rich, N-terminal, IPR003616=Post-SET domain, IPR001965=Zinc finger, PHD-type" CG3848 16-Dec-15 2015_12 WBGene00011729(set-16) "ENSG00000055609(MLL3),ENSG00000167548(MLL2)" " oogenesis stage | stage >=S10 && adult stage | female , embryonic stage | early , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 8-11 , embryonic stage | stage >=13 , larval stage | third instar , oogenesis stage | stage >=S8 && adult stage | female " " oocyte

,

ubiquitous , mesoderm

, anterior embryonic/larval midgut

, embryonic brain

, ventral nerve cord

, posterior embryonic/larval midgut

, imaginal disc

, embryonic/larval salivary gland

, nurse cell

" "viable,fertile,wild-type,non-enhancer of variegation,non-suppressor of variegation,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "eye,ommatidium,morphogenetic furrow,somatic clone,wing vein" FBgn0035769 CTCF CTCF http://flybase.net/reports/FBgn0035769.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000976=transcription regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0046872=metal ion binding, 0043035=chromatin insulator sequence binding" "0006349=regulation of gene expression by genetic imprinting, 0007379=segment specification, 0045892=negative regulation of transcription, DNA-templated, 0043007=maintenance of rDNA" 0005634=nucleus "CCCTC-binding factor, dCTCF, CCCTC-Binding Factor, CG8591" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG8591 16-Dec-15 2015_12 ENSDARG00000056621(ctcf) WBGene00012385(Y5F2A.4) ENSXETG00000015615(CTCF) "ENSMUSG00000005698(Ctcf),ENSMUSG00000070495(Ctcfl)" "ENSG00000102974(CTCF),ENSG00000124092(CTCFL)" "viable,fertile,enhancer of variegation,non-enhancer of variegation,lethal,recessive,suppressor of variegation,non-suppressor of variegation,partially lethal - majority live,visible,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during pupal stage" "wing,male genitalia,abdominal segment 4,abdominal tergite 5,abdominal sternite 6,abdominal tergite 7,abdominal sternite bristle,abdominal sternite 7,abdominal tergite 7 & abdominal sternite bristle0463),abdominal sternite 6 & abdominal sternite bristle,abdominal tergite 4,abdominal sternite 5,abdominal segment 5,abdominal tergite 7 & abdominal sternite bristle,abdominal sternite 6 & abdominal sternite bristle0463)" FBgn0066120 E(sda)O E(sda)O http://flybase.net/reports/FBgn0066120.html gene "0009612=response to mechanical stimulus, 0007638=mechanosensory behavior" Line O 16-Dec-15 2015_12 bang sensitive FBgn0003720 tll tailless http://flybase.net/reports/FBgn0003720.html protein_coding_gene "0008270=zinc ion binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003707=steroid hormone receptor activity, 0003677=DNA binding" "0055057=neuroblast division, 0002121=inter-male aggressive behavior, 0043401=steroid hormone mediated signaling pathway, 0001708=cell fate specification, 0023061=signal release, 0045165=cell fate commitment, 0001746=Bolwig's organ morphogenesis, 0009948=anterior/posterior axis specification, 0051726=regulation of cell cycle, 0048749=compound eye development, 0007362=terminal region determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035271=ring gland development, 0014019=neuroblast development, 0007369=gastrulation, 0016319=mushroom body development, 0008293=torso signaling pathway, 0001748=optic lobe placode development, 0006351=transcription, DNA-templated" 0005634=nucleus "TLL, Tailless, Tailles, CG1378, Tll, dm-tll, NR2E2, TAILLESS" "IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type" CG1378 16-Dec-15 2015_12 ENSDARG00000017107(nr2e1) WBGene00003657(nhr-67) " embryonic stage | stage 7,8 , embryonic stage , embryonic stage | stage 4 , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | syncytial blastoderm , embryonic stage | stage 15 , embryonic stage | stage 10,11 , embryonic stage | stage 10 , embryonic stage | stage 9,10 , embryonic stage | early , embryonic stage | stage 4-17 , embryonic stage && larval stage " " Pc3 neuroblast

, procephalic neuroblast

, organism | 80-100% egg length

, optic lobe | primoridum

, organism | 70-90% egg length

,

0-20% egg length , Pc2 neuroblast

, visual primordium

,

90-100% egg length , embryonic protocerebral neuromere

, posterior protocerebral neuroblast

, intercalary segment

,

terminal ,

0-10% egg length , posterior deuterocerebral neuromere

, organism | 0-20% egg length

, larval brain

, Pa4 neuroblast

,

posterior , Pa3 neuroblast

, protocerebrum

, organism | 80-90% egg length

, procephalic neurogenic region

, optic lobe

" " embryonic stage | stage 4 , embryonic stage | syncytial blastoderm , embryonic stage | stage 5 " " organism | 80-100% egg length

,

0-20% egg length , organism | 70-90% egg length

, organism | 0-20% egg length

" "lethal,recessive,behavior defective,male limited,neuroanatomy defective,cell cycle defective,wild-type,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially,increased cell death,viable,visible" "embryonic/larval optic lobe,Bolwig organ,anterior protocerebral neuromere,posterior protocerebral neuromere,mushroom body | adult stage,adult mushroom body,brain | larval stage,brain | pupal stage,embryonic small intestine,gonad,embryonic dorsal epidermis,abdominal segment 8,telson,embryo,cephalopharyngeal skeleton,filzkorper,embryonic/larval anus,embryonic/larval posterior spiracle,embryonic/larval hindgut,Malpighian tubule,longitudinal visceral muscle primordium,embryonic abdominal segment 8,anal pad,Malpighian tubule primordium,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,tracheal pit,embryonic hindgut,mushroom body neuroblast,somatic clone,embryonic/larval gut,denticle belt & abdominal segment 8,embryonic brain,embryonic central brain,pars intercerebralis,protocerebrum,ganglion mother cell,corpus cardiacum primordium,embryonic/larval mushroom body,embryonic/larval protocerebrum,presumptive embryonic/larval central nervous system,trichogen cell" FBgn0000448 Hr46 Hormone receptor-like in 46 http://flybase.net/reports/FBgn0000448.html "FBgn0019719, FBgn0026805, FBgn0033496" protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0004887=thyroid hormone receptor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0016319=mushroom body development, 0040034=regulation of development, heterochronic, 0043401=steroid hormone mediated signaling pathway, 0007552=metamorphosis, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG33183, Dhr3, l(2)k09242, DHR3, 12.6, NR1F4, Hormone receptor-like 46, dHR3, hr46, HR3, CG11823, DmRORalpha, CG12208, D, 2.4, unnamed, Hormone receptor 3, Complementation group D, l(2)46CFi, Hr3, hormone receptor 3" "IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR001728=Thyroid hormone receptor, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type" CG33183 16-Dec-15 2015_12 "ENSDARG00000033498(rorb),ENSDARG00000001910(rorab),ENSDARG00000017780,ENSDARG00000057231(rorca),ENSDARG00000031768(roraa)" WBGene00003622(nhr-23) "ENSXETG00000021123(RORA),ENSXETG00000008148(RORB)" "ENSMUSG00000036192(Rorb),ENSMUSG00000032238(Rora),ENSMUSG00000028150(Rorc)" "ENSG00000198963(RORB),ENSG00000069667(RORA),ENSG00000143365(RORC)" " larval stage | first instar , embryonic stage | mid , pupal stage , larval stage | third instar , larval stage | second instar " "developmental rate defective,large body,viable,fertile,female sterile,decreased cell number,cell non-autonomous,partially lethal - majority die,some die during larval stage,lethal,recessive,increased cell death,conditional,lethal - all die before end of embryonic stage,some die during embryonic stage,polyphasic,visible,heat sensitive,somatic clone,neuroanatomy defective" "eye disc,conditional,wing,wing hair,heat sensitive,presumptive embryonic/larval peripheral nervous system,trachea & cuticle,taenidial fold,puparium,adult head,embryonic/larval salivary gland,somatic clone,macrochaeta & adult head | somatic clone,macrochaeta & adult thorax | somatic clone,adult cuticle,macrochaeta,macrochaeta & adult abdomen | somatic clone,macrochaeta & adult abdomen,longitudinal connective,posterior,adult mushroom body,trichogen cell" FBgn0010516 wal walrus http://flybase.net/reports/FBgn0010516.html "FBgn0027557, FBgn0027893, FBgn0044469" protein_coding_gene "0009055=electron carrier activity, 0050660=flavin adenine dinucleotide binding" "0007424=open tracheal system development, 0048567=ectodermal digestive tract morphogenesis, 0002009=morphogenesis of an epithelium, 0006119=oxidative phosphorylation, 0008258=head involution, 0007443=Malpighian tubule morphogenesis" "0005811=lipid particle, 0005759=mitochondrial matrix, 0017133=mitochondrial electron transfer flavoprotein complex" "CG8996, ETF, BcDNA:LD07532, unnamed, ETFA, Etf, l(2)02516, P447, Electron transfer flavoprotein, Electron transfer flavoprotein alpha-subunit, Electron transfer flavoprotein alpha subunit, BcDNA:GH09945, EP2253, BcDNA.LD07532" "IPR018206=Electron transfer flavoprotein, alpha subunit, C-terminal, conserved site, IPR029035=DHS-like NAD/FAD-binding domain, IPR014731=Electron transfer flavoprotein, alpha subunit, C-terminal, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR014730=Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, IPR001308=Electron transfer flavoprotein, alpha subunit" CG8996 16-Dec-15 2015_12 YPR004C(AIM45) WBGene00009187(F27D4.1) ENSXETG00000015322(etfa) ENSMUSG00000032314(Etfa) ENSG00000140374(ETFA) "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,maternal effect,neuroanatomy defective,viable" "Malpighian tubule primordium,embryonic Malpighian tubule,embryonic/larval pharynx,embryonic/larval proventriculus,embryonic/larval esophagus,midgut constriction,embryonic head,embryonic/larval trachea,embryonic/first instar larval cuticle,maternal effect,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0002565 Lsp2 Larval serum protein 2 http://flybase.net/reports/FBgn0002565.html FBgn0036251 protein_coding_gene 0045735=nutrient reservoir activity "0016201=synaptic target inhibition, 0008045=motor neuron axon guidance" "0005811=lipid particle, 0005576=extracellular region, 0005616=larval serum protein complex" "CG11538, Pt-1, LHP, LSP2, C23, Lsp-2, larval serum protein 2, CG6806, Protein-1, LSP-2, DmeLSP2, LSP 2, Larval serum protein-2, larval-hemolymph-protein" "IPR000896=Hemocyanin/hexamerin middle domain, IPR014756=Immunoglobulin E-set, IPR008922=Uncharacterised domain, di-copper centre, IPR013788=Hemocyanin/hexamerin, IPR005204=Hemocyanin, N-terminal, IPR005203=Hemocyanin, C-terminal" CG6806 16-Dec-15 2015_12 " larval stage | second instar -- larval stage | third instar , larval stage | third instar , adult stage " " embryonic/larval fat body

, adult head | restricted

" larval stage | second instar -- larval stage | third instar embryonic/larval fat body

"lethal,recessive,visible" tergite FBgn0035145 MED14 Mediator complex subunit 14 http://flybase.net/reports/FBgn0035145.html protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0005515=protein binding" "0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex, 0070847=core mediator complex" "Trap170, p160, CG12031, Med14, dTRAP170" "IPR013947=Mediator complex, subunit Med14" CG12031 16-Dec-15 2015_12 ENSDARG00000009953(med14) WBGene00004343(rgr-1) ENSXETG00000015502(MED14) ENSMUSG00000064127 ENSG00000180182(MED14) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC08235 IK -0.817226408 2.553172308 -0.18232037 0.476510348 2.008226034 5.287924467 FBgn0038607 hmw hemingway http://flybase.net/reports/FBgn0038607.html FBgn0044677 protein_coding_gene "0050910=detection of mechanical stimulus involved in sensory perception of sound, 0007288=sperm axoneme assembly, 0007283=spermatogenesis, 0044458=motile cilium assembly, 0007291=sperm individualization" "Hmw, anon-WO0140519.198, CG7669" IPR029488=KIAA1430 homologue CG7669 16-Dec-15 2015_12 ENSDARG00000056381(zgc:85910) ENSMUSG00000031631(4933411K20Rik) "viable,male sterile,female fertile,auditory perception defective,neurophysiology defective" "spermatozoon,spermatid axoneme" FBgn0024592 l(2)k04102 lethal (2) k04102 http://flybase.net/reports/FBgn0024592.html gene 41/2 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0044823 Spec2 Spec2 http://flybase.net/reports/FBgn0044823.html "FBgn0037349, FBgn0046780, FBgn0064769" protein_coding_gene "0005198=structural molecule activity, 0017048=Rho GTPase binding" "0009966=regulation of signal transduction, 0035023=regulation of Rho protein signal transduction" "0005938=cell cortex, 0005886=plasma membrane" "SPEC, Small Protein Effector of Cdc42 2, BcDNA:LD24607, CG14672, dSPEC, SPEC2, dSPEC2" IPR000095=CRIB domain CG14672 16-Dec-15 2015_12 ENSDARG00000023724(cdc42se1) "ENSXETG00000008962(cdc42se2),ENSXETG00000022051(TEgg060j13.1)" ENSMUSG00000052298(Cdc42se2) ENSG00000158985(CDC42SE2) "viable,fertile" "germline cell,male" FBgn0030240 CG2202 http://flybase.net/reports/FBgn0030240.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type" CG2202 16-Dec-15 2015_12 YPR186C(PZF1) WBGene00010770(K11D2.4) viable DRSC19841 IEK 3.282157117 2.841580072 -2.664796867 -0.144167584 1.690292163 1.124090199 FBgn0033246 ACC Acetyl-CoA carboxylase http://flybase.net/reports/FBgn0033246.html FBgn0033245 protein_coding_gene "0046872=metal ion binding, 0003989=acetyl-CoA carboxylase activity, 0005524=ATP binding, 0004075=biotin carboxylase activity" "0071329=cellular response to sucrose stimulus, 0040008=regulation of growth, 0000902=cell morphogenesis, 1903827=regulation of cellular protein localization, 0009744=response to sucrose, 0030111=regulation of Wnt signaling pathway, 0005977=glycogen metabolic process, 0006633=fatty acid biosynthetic process, 0008593=regulation of Notch signaling pathway, 0019432=triglyceride biosynthetic process" "0005737=cytoplasm, 0005811=lipid particle" "FBgn0043811, CG11198, Acetyl CoA carboxylase, Acetyl-CoA carboxylase, acetyl coenzyme A carboxylase, acetyl coA carboxylase, ACoT, acetyl CoA carboxylase, acetyl-CoA carboxylase, dACC, A1Z784_DROME, aceto-acetyl-CoA-thiolase, CG8723, DmACC, ACC, acetyl-coenzyme A carboxylase" "IPR000022=Carboxyl transferase, IPR011054=Rudiment single hybrid motif, IPR005482=Biotin carboxylase, C-terminal, IPR005481=Biotin carboxylase-like, N-terminal domain, IPR001882=Biotin-binding site, IPR000089=Biotin/lipoyl attachment, IPR011764=Biotin carboxylation domain, IPR013816=ATP-grasp fold, subdomain 2, IPR011761=ATP-grasp fold, IPR013537=Acetyl-CoA carboxylase, central domain, IPR013815=ATP-grasp fold, subdomain 1, IPR029045=ClpP/crotonase-like domain, IPR011053=Single hybrid motif, IPR011762=Acetyl-coenzyme A carboxyltransferase, N-terminal, IPR016185=Pre-ATP-grasp domain, IPR005479=Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR011763=Acetyl-coenzyme A carboxyltransferase, C-terminal" CG11198 16-Dec-15 2015_12 "ENSDARG00000059638,ENSDARG00000061994(LOC556236)" "YNR016C(ACC1),YMR207C(HFA1)" WBGene00004076(pod-2) "ENSXETG00000008955(ACACA),ENSXETG00000022294(ACACB)" "ENSMUSG00000020532(Acaca),ENSMUSG00000042010(Acacb)" "ENSG00000132142(ACACA),ENSG00000076555(ACACB)" "lethal - all die during larval stage,feeding behavior defective,visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during embryonic stage,viable,recessive" "embryonic/larval oenocyte | second instar larval stage,embryonic/larval tracheal system | larval stage,embryonic/larval spiracle | larval stage,wing,embryonic/larval brain,embryonic/larval fat body,embryonic/larval oenocyte" DRSC06059 IE -1.446129177 -2.893552572 -1.810274686 2.022327349 0.424030367 -0.579232127 FBgn0011763 Dp DP transcription factor http://flybase.net/reports/FBgn0011763.html FBgn0002082 protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008134=transcription factor binding, 0005515=protein binding" "0007113=endomitotic cell cycle, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0006357=regulation of transcription from RNA polymerase II promoter, 0010628=positive regulation of gene expression, 0045476=nurse cell apoptotic process, 0045850=positive regulation of nurse cell apoptotic process, 0048477=oogenesis, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0000278=mitotic cell cycle, 0051726=regulation of cell cycle, 0006355=regulation of transcription, DNA-templated, 0007307=eggshell chorion gene amplification" "0005634=nucleus, 0031523=Myb complex, 0035189=Rb-E2F complex" "DDP1, dDp, TFPD2, l(2)vr10, DP, dp, DP1, CG4654, dimerization partner, lethal(2)49Fk, l(2)49Fk, vr10, Dp1, dDP, DmDP, dDP1, 49Fk" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR003316=E2F/DP family, winged-helix DNA-binding domain, IPR015648=Transcription factor DP, IPR014889=Transcription factor DP, C-terminal" CG4654 16-Dec-15 2015_12 "ENSDARG00000019293(tfdp1l),ENSDARG00000016304(tfdp1),ENSDARG00000042835(tfdp2)" "ENSXETG00000014750(TFDP2),ENSXETG00000017776(tfdp1)" "ENSMUSG00000032411(Tfdp2),ENSMUSG00000038482(Tfdp1)" "ENSG00000114126(TFDP2),ENSG00000198176(TFDP1),ENSG00000183434(TFDP3)" " larval stage | third instar , embryonic stage | early , embryonic stage " " testis

, spermatocyte

, larval brain

, morphogenetic furrow | anterior to

, morphogenetic furrow | posterior to

, ventral nerve cord

, eye disc

, ventral thoracic disc

, antennal disc

, optic lobe

, embryonic central nervous system

" "viable,fertile,neuroanatomy defective,locomotor behavior defective,cell death defective,wild-type,female sterile,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of pupal stage,visible,some die during pupal stage,decreased cell death,sterile,partially lethal - majority live,germline clone,non-suppressor of variegation,dominant,lethal - all die before end of larval stage,some die during larval stage" "dopaminergic neuron,nurse cell,eye,heterochromatin & nurse cell, with Dpa2,mitotic cell cycle,thorax & macrochaeta,head & macrochaeta,abdomen,wing disc,nucleus,ommatidium,interommatidial bristle,wing vein,macrochaeta,chorion,follicle cell & nucleus,tergite,ovary,heterochromatin & nurse cellvg56),nuclear membrane & nurse cellvg56),polar body nucleus,follicle cell,dorsal appendage,germline clone,egg,embryonic/first instar larval cuticle,nurse cell & actin filament | germ-line clone,ectopic,anterior midgut proper primordium & S phase,eye disc,oocyte,chorion | germline clone,heterochromatin & nurse cell, with Dphs.PD,trichogen cell,mesothoracic tergum" DRSC07402 IEK -3.77733035 -2.912652207 3.79602552 -4.226216377 11.03756704 12.63605456 FBgn0267407 crl courtless http://flybase.net/reports/FBgn0267407.html gene "0007283=spermatogenesis, 0008049=male courtship behavior, 0007140=male meiosis" "UbcD7, Col, col" 16-Dec-15 2015_12 "male sterile,recessive,courtship behavior defective,male,female fertile,meiotic cell cycle defective" "spermatid,meiotic cell cycle | male" FBgn0030937 CG15042 http://flybase.net/reports/FBgn0030937.html protein_coding_gene CG15042 16-Dec-15 2015_12 "viable,visible" "chaeta,supernumerary" FBgn0035598 CG4669 http://flybase.net/reports/FBgn0035598.html FBgn0044681 protein_coding_gene anon-WO0140519.194 CG4669 16-Dec-15 2015_12 viable FBgn0044347 l(2)k9 lethal (2) k9 http://flybase.net/reports/FBgn0044347.html gene 16-Dec-15 2015_12 lethal FBgn0032706 Irk3 Inwardly rectifying potassium channel 3 http://flybase.net/reports/FBgn0032706.html protein_coding_gene 0005242=inward rectifier potassium channel activity "0042391=regulation of membrane potential, 0006813=potassium ion transport, 0035220=wing disc development" 0016021=integral component of membrane "CG10369, irk3, dKirIII" "IPR016449=Potassium channel, inwardly rectifying, Kir, IPR014756=Immunoglobulin E-set, IPR013518=Potassium channel, inwardly rectifying, Kir, cytoplasmic" CG10369 16-Dec-15 2015_12 "viable,short lived,nutrition conditional,touch sensitivity defective,visible,size defective,partially lethal - majority die,lethal" "wing,wing vein,wing hinge" FBgn0027653 l(1)CL lethal (1) Cell Lethal http://flybase.net/reports/FBgn0027653.html gene "l(1)cl, CLX" 16-Dec-15 2015_12 "cell lethalcell lethal,somatic clone,lethal,recessive" "eye,somatic clone" FBgn0260345 GSd405 http://flybase.net/reports/FBgn0260345.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0051852 Tap42 Two A-associated protein of 42kDa http://flybase.net/reports/FBgn0051852.html FBgn0032510 protein_coding_gene "0022008=neurogenesis, 0009966=regulation of signal transduction" "CG31852, Tap-42/CG31852, CG6537, dTap42" IPR007304=TAP42-like protein CG31852 16-Dec-15 2015_12 ENSDARG00000002184(zgc:55347) YMR028W(TAP42) WBGene00022193(ppfr-4) ENSXETG00000023188() "ENSMUSG00000031221(Igbp1),ENSMUSG00000046717(Igbp1b)" ENSG00000089289(IGBP1) "lethal - all die before end of larval stage,recessive,some die during third instar larval stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "spindle,mitosis,embryonic/larval brain,embryonic/larval neuroblast,ganglion mother cell" DRSC24168 K 0.167445607 -0.098296183 0.217375471 -0.517962664 0.154041177 2.605901039 FBgn0041191 Rheb Ras homolog enriched in brain ortholog (H. sapiens) http://flybase.net/reports/FBgn0041191.html FBgn0037343 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0016049=cell growth, 0030307=positive regulation of cell growth, 0010507=negative regulation of autophagy, 0007446=imaginal disc growth, 2000377=regulation of reactive oxygen species metabolic process, 0007264=small GTPase mediated signal transduction, 0045793=positive regulation of cell size, 0000082=G1/S transition of mitotic cell cycle, 0032008=positive regulation of TOR signaling, 0007411=axon guidance, 0042594=response to starvation, 0090070=positive regulation of ribosome biogenesis, 0006629=lipid metabolic process, 0005975=carbohydrate metabolic process, 0045727=positive regulation of translation, 0010506=regulation of autophagy, 0035264=multicellular organism growth, 0051124=synaptic growth at neuromuscular junction, 0042331=phototaxis, 0042254=ribosome biogenesis" 0016020=membrane "RHEB, CG1081, Ras homology enriched in brain, DmRheb, RAS homolog enriched in brain, RheB, dRheb, Ras homologue enriched in brain, DReb, Ras homolog enriched in brain, Dm Rheb, rheb, Rheb, Q9VND8" "IPR020849=Small GTPase superfamily, Ras type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain" CG1081 16-Dec-15 2015_12 ENSDARG00000039162(rheb) WBGene00010038(rheb-1) ENSXETG00000009724(RHEB) ENSMUSG00000028945(Rheb) ENSG00000106615(RHEB) "lethal,recessive,increased cell size,somatic clone,large body,neuroanatomy defective,cell death defective,lethal - all die before end of larval stage,some die during larval stage,small body,cell size defective,developmental rate defective,eclosion rhythm defective,dominant,drug conditional,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,decreased cell size,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,partially lethal - majority die,decreased cell number,visible,chemical sensitive,nutrition conditional,phototaxis defective,neurophysiology defective,mitotic cell cycle defective,increased cell death" "embryonic/larval neuroblast,eye,ommatidium,fat body,somatic clone,synapse796,wing disc,somatic clone | third instar larval stage,embryonic/larval fat body,embryonic/larval hindgut,head,interommatidial bristle,supernumerary,antenna,embryonic/larval neuromuscular junction | third instar larval stage,adult brain,wing,imaginal disc,embryonic/larval salivary gland,ovary,G1 phase,S phase,dorsal compartment,posterior compartment,anterior compartment,photoreceptor cell R7,nutrition conditional,photoreceptor cell R8,embryonic/larval neuromuscular junction,embryonic/larval principal midgut epithelial cell,temperature conditional,intestinal stem cell,photoreceptor cell,salivary gland,conditional,mitotic cell cycle,nucleolusen-e16E,1st posterior cell,rhabdomereGMR.PU" DRSC12148 I -0.508815162 2.423755694 -1.342542655 0.372589988 0.982622258 0.553414123 FBgn0065244 l(2)SH2141 lethal (2) SH2141 http://flybase.net/reports/FBgn0065244.html gene l(2)SH2 2141 16-Dec-15 2015_12 "lethal,recessive" FBgn0033167 CG1701 http://flybase.net/reports/FBgn0033167.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space CG1701 16-Dec-15 2015_12 viable FBgn0040070 Trx-2 thioredoxin-2 http://flybase.net/reports/FBgn0040070.html "FBgn0032134, FBgn0051884, FBgn0062183" protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" "0006974=cellular response to DNA damage stimulus, 0006662=glycerol ether metabolic process, 0008340=determination of adult lifespan, 0050832=defense response to fungus, 0045454=cell redox homeostasis, 0006979=response to oxidative stress" 0005634=nucleus "thioredoxin, CG3864, DmTrx-2, 31884, Thioredoxin-2, DTrx-2, Trx, CG31884, DmelTrx-2, anon-WO0118547.188, dmtrx-2" "IPR005746=Thioredoxin, IPR013766=Thioredoxin domain, IPR012336=Thioredoxin-like fold, IPR017937=Thioredoxin, conserved site" CG31884 16-Dec-15 2015_12 "ENSDARG00000044125(zgc:92903),ENSDARG00000031435(zgc:56493)" "YGR209C(TRX2),YLR043C(TRX1)" WBGene00021548(Y44E3A.3) "ENSXETG00000002592(txn),ENSXETG00000010267()" ENSMUSG00000028367(Txn1) ENSG00000136810(TXN) " larval stage , " " imaginal disc

,

" "chemical resistant,immune response defective,long lived,viable,fertile,short lived,locomotor behavior defective,conditional,chemical sensitive,oxidative stress response defective,male fertile" crystal cell FBgn0004569 aos argos http://flybase.net/reports/FBgn0004569.html "FBgn0010878, FBgn0011388, FBgn0011502, FBgn0011505, FBgn0011527, FBgn0014382, FBgn0020286" protein_coding_gene "0048019=receptor antagonist activity, 0005154=epidermal growth factor receptor binding" "0045596=negative regulation of cell differentiation, 0042067=establishment of ommatidial planar polarity, 0007482=haltere development, 0009996=negative regulation of cell fate specification, 2000737=negative regulation of stem cell differentiation, 0007472=wing disc morphogenesis, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0001654=eye development, 0050768=negative regulation of neurogenesis, 0007455=eye-antennal disc morphogenesis, 0060233=oenocyte delamination, 0035215=genital disc development, 0007474=imaginal disc-derived wing vein specification, 0016318=ommatidial rotation, 0007476=imaginal disc-derived wing morphogenesis, 0007411=axon guidance, 0043065=positive regulation of apoptotic process, 0046331=lateral inhibition, 0030707=ovarian follicle cell development" 0005576=extracellular region "l(3)05845, sty, aos, giant lens, l(3)rJ472, rlt, roulette, CG4531, strawberry, Aos, Argos, l(3)rQ526, DmAos, l(3)rJ812, arg, l(3)05959, gil, l(3)j5E11, argos" "IPR021633=Antagonist of EGFR signalling, Argos" CG4531 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage 9-16 , larval stage | third instar " " organism | pair rule

, midline glial cell

, epidermis | ventral

, eye-antennal disc

" "song defective,viable,fertile,partially lethal - majority die,visible,lethal,partially,cell polarity defective,somatic clone,recessive,dominant,wild-type,visual behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,heat sensitive,increased cell death,decreased cell number,increased cell size,size defective,body color defective,some die during pupal stage" "midgut,eye,wing vein L4,dorsal appendage,maternal effect,rhabdomere,eye photoreceptor cell,optic lobe,mystery cell,cone cell,interommatidial bristle & eye | precursor,ommatidium,photoreceptor cell,ectopic,midline glial cell,retina,pigment cell,somatic clone,wing,eye photoreceptor cell & axon,lens,lamina,medulla,lobula,optic nerve,bract,supernumerary,posterior compartment,photoreceptor cell R3,photoreceptor cell R4,ommatidial precursor cluster,posterior,denticle belt,abdominal lateral pentascolopidial chordotonal organ lch5,embryonic/larval oenocyte,dorsal acute muscle,pericardial cell,precursor,dorsal oblique muscle,1st posterior cell,2nd posterior cell,presumptive embryonic/larval central nervous system,chordotonal organ,lateral,photoreceptor cell R8,hypocerebral ganglion,embryonic/larval recurrent nerve,frontal ganglion,embryonic/larval optic lobe,hypostomal sclerite,genital disc primordium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R5,photoreceptor cell R6,embryonic head,embryonic ventral epidermis,oenocyte primordium,embryonic/larval oenocyte precursor,embryonic/larval brain,embryonic/larval neuroblast,heat sensitive,secondary pigment cell,tertiary pigment cell,Malpighian tubule,wing vein,commissure,ventral nerve cord,maxillary palpus,interommatidial bristle,abdominal sternite bristle,retina & axon,lamina & glial cell,embryonic/larval optic neuropil,mesothoracic dorsal triscolopidial chordotonal organ dch3,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,visual primordium,wing vein L5,mesothoracic tibial bract,mesothoracic tarsal segment 1 & bract-537.4,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,taste bristle & leg | ectopic-537.4,mesothoracic tarsal segment 1 & bract | dorsalDll-md23,mesothoracic tarsal segment 1 & bractDll-md23,adult apodeme & legDll-md23,unguis,taste bristle & leg | ectopicDll-md23,microchaeta & mesothoracic tergum-C253,macrochaeta & mesothoracic tergum-C253,anterior supraalar bristle,posterior supraalar bristle,posterior postalar bristle,anterior postalar bristle,anterior dorsocentral bristle,anterior scutellar bristle,posterior scutellar bristle,anterior crossvein,embryonic/larval salivary gland,Bolwig organ,Bolwig nerve,glial cell & antennal dischs.PB,mesothoracic tergum,wing disc,pretarsus,crossvein,wing vein L3,posterior crossvein,photoreceptor,egg,egg operculum,chorion,micropyle,wing vein L2,chaeta" FBgn0036844 Mkp3 Mitogen-activated protein kinase phosphatase 3 http://flybase.net/reports/FBgn0036844.html FBgn0036845 protein_coding_gene "0016791=phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0017017=MAP kinase tyrosine/serine/threonine phosphatase activity" "0016337=single organismal cell-cell adhesion, 0042127=regulation of cell proliferation, 0043409=negative regulation of MAPK cascade, 0006470=protein dephosphorylation, 0002385=mucosal immune response, 0007428=primary branching, open tracheal system, 0000188=inactivation of MAPK activity, 0035160=maintenance of epithelial integrity, open tracheal system, 0007474=imaginal disc-derived wing vein specification" "0005737=cytoplasm, 0005829=cytosol" "MAPK phosphatase 3, CG14081, unnamed, MKP-3-like, MKP3, MAPK phosphatase-3, Map kinase phosphatase 3, CG14080, ERK-inhibitory phosphatase, MAP Kinase Phosphatase 3, mkp3, DMKP-3, dMKP3, mkp-3, MKP-like, Drosophila MKP-3, Dmkp3" "IPR020422=Dual specificity protein phosphatase domain, IPR008343=Mitogen-activated protein (MAP) kinase phosphatase, IPR001763=Rhodanese-like domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR024950=Dual specificity phosphatase, IPR029021=Protein-tyrosine phosphatase-like" CG14080 16-Dec-15 2015_12 "ENSDARG00000032738(LOC100330065),ENSDARG00000070914(dusp6)" WBGene00003043(lip-1) "ENSXETG00000021871(dusp6),ENSXETG00000007698(DUSP9)" "ENSMUSG00000053716(Dusp7),ENSMUSG00000019960(Dusp6),ENSMUSG00000031383(Dusp9)" "ENSG00000164086(DUSP7),ENSG00000139318(DUSP6),ENSG00000130829(DUSP9)" larval stage | third instar eye disc | posterior to morphogenetic furrow & stripe

"visible,wild-type,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,cell shape defective,short lived,increased cell death,partially lethal - majority die" "eye,wing vein,supernumerary,eye photoreceptor cell,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R7,ectopic,dorsal branch primordium,photoreceptor cell,midgut,tracheal branch primordium,tracheolar cell,ganglionic branch primordium,embryonic trachea & cortical actin cytoskeletonbtl.PS,adult posterior midgut epithelium,wing vein L2,wing vein L3,wing vein L4,wing vein L5,wing,wing hinge,macrochaeta,mesothoracic tergum" DRSC10085 EK 0.583683296 0.176752916 -1.726001296 -0.337152188 -1.576055112 -0.134120798 FBgn0000137 ase asense http://flybase.net/reports/FBgn0000137.html protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0042803=protein homodimerization activity, 0046982=protein heterodimerization activity" "0007400=neuroblast fate determination, 0061382=Malpighian tubule tip cell differentiation, 0006355=regulation of transcription, DNA-templated, 0007422=peripheral nervous system development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007417=central nervous system development, 0008407=chaeta morphogenesis, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0022416=chaeta development, 0045839=negative regulation of mitotic nuclear division, 0007399=nervous system development" 0005634=nucleus "EG:165H7.2, T1A, T1a, sc/T8, as-T8, AS-C T8ase, T1, ASC, ascT8, Asense, bHLHc28, CG3258, AS-T8, T8, Ase, AS-C T8" "IPR015660=Achaete-scute transcription factor-related, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG3258 16-Dec-15 2015_12 WBGene00001950(hlh-3) "ENSMUSG00000020052(Ascl1),ENSMUSG00000009248(Ascl2)" " larval stage | third instar , embryonic stage , embryonic stage | stage >=10 , embryonic stage | stage >=11 , embryonic stage | stage 8-11 " " morphogenetic furrow | posterior to

, ganglion mother cell

, embryonic optic lobe primordium

, posterior embryonic/larval midgut

, larval optic lobe

, stage 2 neuroblast

, imaginal disc

, antennal disc

, neuroblast

, procephalic neurogenic region

, sensory mother cell

, labrum

, embryonic/larval midgut

, stage 3 neuroblast

, precursor cell of the stomatogastric nervous system

, larval central nervous system

, embryonic peripheral nervous system

, dorsal mesothoracic disc

, stage 1 neuroblast

, larval optic lobe | anlagen

, ventral thoracic disc

, posterior midgut proper primordium

, eye disc

, embryonic central nervous system

, embryonic ganglion mother cell

, larval brain | restricted

, optic lobe

" " embryonic stage , larval stage | third instar , embryonic stage | stage >=10 " " stage 1 neuroblast

, stage 3 neuroblast

, embryonic ganglion mother cell

, sensory mother cell

, larval optic lobe

, embryonic/larval midgut

, dorsal mesothoracic disc

, stage 2 neuroblast

, larval brain | restricted

, neuroblast

, antennal disc

, ventral thoracic disc

, larval optic lobe | anlagen

" "visible,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,viable" "macrochaeta,heat sensitive,microchaeta,sense organ,external sensory organ,ectopic,wing sensillum,sensillum campaniformium | ectopic & wingC-765,chaeta | ectopic & mesothoracic tergumC-765,mechanosensory chaeta,sensory mother cell,embryonic/larval optic lobe" FBgn0011818 oaf out at first http://flybase.net/reports/FBgn0011818.html "FBgn0004866, FBgn0005565" protein_coding_gene "0007399=nervous system development, 0016321=female meiosis chromosome segregation, 0007562=eclosion" "transcript-near-decapentaplegic, tnd, transcript near decapentaplegic, l(2)22Fb, near dpp complementation group 1, out at first, l(2)ND1, CG9884" IPR026315=Out at first protein CG9884 16-Dec-15 2015_12 ENSXETG00000017014(Q4QQN6_XENTR) ENSMUSG00000032014(Oaf) ENSG00000184232(OAF) " adult stage && oogenesis stage , larval stage | third instar && spermatogenesis , embryonic stage , oogenesis stage && adult stage | female , embryonic stage | stage >15 , embryonic stage | stage 11 " " oocyte

, spermatocyte

,

ubiquitous , ovary

, gonad

, ventral midline | segmentally repeated

, nurse cell

, embryonic brain

, ventral nerve cord | segmentally repeated

, germ band | restricted

, testis

" "viable,male fertile,female fertile,lethal,recessive,meiotic cell cycle defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" "wing,peripheral nervous system,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,dorsal closure embryo" FBgn0031144 CG1529 http://flybase.net/reports/FBgn0031144.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1529 16-Dec-15 2015_12 viable FBgn0031282 Pex12 Peroxin 12 http://flybase.net/reports/FBgn0031282.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding, 0008022=protein C-terminus binding" "0007031=peroxisome organization, 0048137=spermatocyte division, 0007286=spermatid development, 0006625=protein targeting to peroxisome" "0005779=integral component of peroxisomal membrane, 0005777=peroxisome" "PEX12, CG3639, peroxin 12, DmelPex12, pex12" "IPR006845=Pex, N-terminal, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017375=Peroxisome assembly protein 12, IPR001841=Zinc finger, RING-type" CG3639 16-Dec-15 2015_12 ENSDARG00000035149(pex12) YMR026C(PEX12) WBGene00004197(prx-12) ENSXETG00000013481(PEX12) ENSMUSG00000018733(Pex12) ENSG00000108733(PEX12) "male sterile,developmental rate defective,cytokinesis defective,meiotic cell cycle defective,viable" "spermatid,testis" FBgn0260054 2L2648 http://flybase.net/reports/FBgn0260054.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0037045 CG10584 http://flybase.net/reports/FBgn0037045.html FBgn0061727 protein_coding_gene anon-WO0118547.713 "IPR019410=Lysine methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG10584 16-Dec-15 2015_12 ENSDARG00000055437(zgc:172067) YNL024C() ENSXETG00000008690(C16orf68) ENSMUSG00000039345(BC024814) ENSG00000067365(METTL22) viable embryonic/larval hemocyte | third instar larval stage FBgn0004363 porin porin http://flybase.net/reports/FBgn0004363.html "FBgn0016759, FBgn0022189, FBgn0024919, FBgn0066003" protein_coding_gene 0008308=voltage-gated anion channel activity "0007005=mitochondrion organization, 0055085=transmembrane transport, 0044070=regulation of anion transport, 0007602=phototransduction, 0030382=sperm mitochondrion organization, 0007291=sperm individualization, 0006839=mitochondrial transport, 0006811=ion transport" "0005739=mitochondrion, 0005811=lipid particle, 0016006=Nebenkern, 0005875=microtubule associated complex, 0005741=mitochondrial outer membrane" "DVDAC, cg6647, Porin, CG6647, PORIN, anon-WO02059370.56, VDAC, Voltage-dependent anion-selective channel, porin 1, POR-1, DmVDAC, DmPorin1, mitochondrial porin, Porin 1, Vdac, l(2)k05123, voltage-dependent anion channel" "IPR027246=Eukaryotic porin/Tom40, IPR001925=Porin, eukaryotic type, IPR023614=Porin domain" CG6647 16-Dec-15 2015_12 "ENSDARG00000013623(vdac2),ENSDARG00000021564(zgc:56235),ENSDARG00000003695(vdac3),ENSDARG00000045132(vdac1)" "YNL055C(POR1),YIL114C(POR2)" WBGene00019900(R05G6.7) "ENSXETG00000009865(vdac2),ENSXETG00000015952(vdac1),ENSXETG00000016789(vdac3)" "ENSMUSG00000021771(Vdac2),ENSMUSG00000020402(Vdac1),ENSMUSG00000008892(Vdac3)" "ENSG00000172974,ENSG00000165637(VDAC2),ENSG00000213585(VDAC1),ENSG00000078668(VDAC3)" "neurophysiology defective,recessive,male fertile,lethal,viable,fertile,short lived,locomotor behavior defective,male sterile,male semi-fertile,female fertile,bang sensitive,female semi-sterile,partially lethal - majority die,some die during larval stage,flight defective" "photoreceptor,mitochondrionMef2.PR,indirect flight muscle,mitochondrion,testis,seminal vesicle,embryonic/larval neuromuscular junction,cystic bulge,waste bag,Nebenkern,mitochondrionBSC143)" FBgn0027499 wde windei http://flybase.net/reports/FBgn0027499.html protein_coding_gene 0005694=chromosome "Windei, CG12340, i10, i119, BcDNA:LD26050, Wde, LD26050" "IPR026085=Activating transcription factor 7-interacting protein, IPR003961=Fibronectin type III" CG12340 16-Dec-15 2015_12 ENSMUSG00000030213(Atf7ip) ENSG00000171681(ATF7IP) "female sterile,recessive,lethal - all die before end of P-stage,some die during P-stage,germline clone,viable,visible,female fertile" "ovariole,oocyte,germline clone,trichogen cell" FBgn0027356 Amph Amphiphysin http://flybase.net/reports/FBgn0027356.html protein_coding_gene 0005543=phospholipid binding "0008104=protein localization, 0042052=rhabdomere development, 0007269=neurotransmitter secretion, 0006937=regulation of muscle contraction, 0048488=synaptic vesicle endocytosis, 0006897=endocytosis, 0045313=rhabdomere membrane biogenesis, 0006887=exocytosis" "0005737=cytoplasm, 0045202=synapse, 0005886=plasma membrane, 0032154=cleavage furrow" "dAmphiphysin, Amp, Damp, amph, DAMP, damph, CG8604, dAmph, dAmp, amphiphysin" "IPR004148=BAR domain, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR001452=SH3 domain, IPR003005=Amphiphysin" CG8604 16-Dec-15 2015_12 "ENSDARG00000042114(LOC563561),ENSDARG00000058820,ENSDARG00000007663(amph)" YDR388W(RVS167) WBGene00010272(amph-1) ENSXETG00000000473(BIN1) "ENSMUSG00000021314(Amph),ENSMUSG00000024381(Bin1)" "ENSG00000136717(BIN1),ENSG00000110934(BIN2)" " embryonic stage | stage 17 , embryonic stage | stage 16 , embryonic stage | stage 13 " " embryonic/larval pharynx

, embryonic/larval hindgut

, embryonic epidermis

, embryonic/larval foregut

, embryonic peripheral nervous system

, pharyngeal muscle

" "hypoactive,viable,fertile,neuroanatomy defective,flightless,neurophysiology defective" "anterior fascicle & synapse,macrochaeta,neuromuscular junction | larval stage,rhabdomere,motor neuron,indirect flight muscle,indirect flight muscle & myofibril,T-tubule,NMJ bouton,rhabdomereGMR.PF,rhabdomere | ectopicGMR.PF" DRSC07578 E 0.300095718 -0.242797624 -1.514751064 -0.138475636 0.824212647 -0.082022781 FBgn0033649 pyr pyramus http://flybase.net/reports/FBgn0033649.html protein_coding_gene 0005104=fibroblast growth factor receptor binding "0021782=glial cell development, 0007507=heart development, 0007498=mesoderm development, 0010002=cardioblast differentiation, 0007442=hindgut morphogenesis, 0007509=mesoderm migration involved in gastrulation, 0007523=larval visceral muscle development, 0060252=positive regulation of glial cell proliferation, 0051451=myoblast migration, 0008347=glial cell migration, 0007526=larval somatic muscle development, 0008543=fibroblast growth factor receptor signaling pathway, 0061320=pericardial nephrocyte differentiation" "Pyr, CG13194, Pyramus, DFGF8-2, FGF8-like2, DmPyr, fgf8-like" "IPR008996=Cytokine, IL-1-like" CG13194 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,cell migration defective,increased cell death" "glial cell,mesoderm,embryonic somatic muscle,embryonic dorsal vessel,embryonic cardioblast,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,segment border muscle,embryonic/larval midgut longitudinal visceral muscle,longitudinal visceral muscle primordium,cell non-autonomous,longitudinal visceral muscle primordium | embryonic stage 12,longitudinal visceral muscle primordium | embryonic stage 13,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 17,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 15,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 14" FBgn0002466 sti sticky http://flybase.net/reports/FBgn0002466.html "FBgn0036295, FBgn0062046" protein_coding_gene "0005524=ATP binding, 0019992=diacylglycerol binding, 0004674=protein serine/threonine kinase activity" "2000431=regulation of cytokinesis, actomyosin contractile ring assembly, 0000915=actomyosin contractile ring assembly, 0035556=intracellular signal transduction, 0006468=protein phosphorylation, 0006325=chromatin organization, 0000281=mitotic cytokinesis, 0007112=male meiosis cytokinesis, 0032465=regulation of cytokinesis, 0032956=regulation of actin cytoskeleton organization" 0005826=actomyosin contractile ring "citron, DCK, Citron, citron kinase, l(3)SG21, Citron K, Sticky, STI, CITRON, cit, CG10522, Citron kinase, Citron Kinase, anon-WO0118547.388, CIT-K, l(3)7m-62, Drosophila citron kinase, l(3)7m62, sti/Citron, dck" "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001180=Citron homology (CNH) domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal" CG10522 16-Dec-15 2015_12 ENSXETG00000012183(CIT) ENSMUSG00000029516(Cit) ENSG00000122966(CIT) "partially lethal - majority die,lethal,cytokinesis defective,lethal - all die before end of P-stage,recessive,some die during P-stage,lethal - all die before end of prepupal stage,some die during prepupal stage,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,male sterile,female semi-sterile,some die during third instar larval stage,heat sensitive,visible,suppressor of variegation,dominant,female sterile,viable,enhancer of variegation" "presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & neuroniro-2),embryonic/larval brain,imaginal disc,contractile ringiro-2),embryonic/larval neuroblast,neuroblast & chromosome,neuroblast,neuroblast & chromosomeF10),S2 cell-line,neuroblast & condensed chromosome,testis,spermatocyte,chromosome | ectopic,filamentous actin,nucleus,actomyosin contractile ring | ectopic,spermatid & NebenkernE44),spermatid & nucleus | supernumeraryE44),spermatocyte ring canal,spermatid & Nebenkern,spermatid & nucleus | supernumerary,eye,ommatidium,eye & ommatidium,nucleus & follicle cell | conditional - heat sensitive,heat sensitive,interommatidial bristle,nucleusey.PB,follicle cell" FBgn0005583 l(1)dh2 lethal (1) discs heterogeneous 2 http://flybase.net/reports/FBgn0005583.html "FBgn0001619, FBgn0001620" gene "l(1)d.het.-2, l(1)het2" 16-Dec-15 2015_12 "mitotic cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0035572 CG13711 http://flybase.net/reports/FBgn0035572.html protein_coding_gene 0032879=regulation of localization HL5 IPR007970=Protein of unknown function DUF733 CG13711 16-Dec-15 2015_12 viable FBgn0001841 l(1)ts1251 lethal (1) ts1251 http://flybase.net/reports/FBgn0001841.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,male sterile" humeral disc FBgn0050271 CG30271 http://flybase.net/reports/FBgn0050271.html "FBgn0034779, FBgn0065004" protein_coding_gene "BcDNA:AT17081, CG13528" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG30271 16-Dec-15 2015_12 "viable,partially lethal - majority die,some die during pupal stage" DRSC30044 K -0.085158772 0.273780846 0.228308577 0.531737044 -1.707474229 -0.065409875 FBgn0015391 glu gluon http://flybase.net/reports/FBgn0015391.html "FBgn0027863, FBgn0062208" protein_coding_gene "0005524=ATP binding, 0000166=nucleotide binding, 0046982=protein heterodimerization activity, 0003682=chromatin binding, 0016887=ATPase activity, 0003677=DNA binding" "0051304=chromosome separation, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0007076=mitotic chromosome condensation, 0000819=sister chromatid segregation, 0000070=mitotic sister chromatid segregation" "0000785=chromatin, 0000796=condensin complex, 0000793=condensed chromosome, 0005737=cytoplasm, 0005694=chromosome, 0005634=nucleus" "DmSMC4, l(2)k08819, Smc4, Gluon, CG11397, anon-WO0118547.156, SMC4, DmSMC4/gluon, gluon, dSMC4, BcDNA.LD20207, BcDNA:LD20207" "IPR024704=Structural maintenance of chromosomes protein, IPR010935=SMCs flexible hinge, IPR003395=RecF/RecN/SMC, N-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG11397 16-Dec-15 2015_12 ENSDARG00000038882(smc4) YLR086W(SMC4) WBGene00004874(smc-4) ENSXETG00000008717(smc4l1) ENSMUSG00000034349(Smc4) ENSG00000113810(SMC4) "increased cell death,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,non-suppressor of variegation,suppressor of variegation,partially,viable,visible" "adult brain,mitosis & nuclear chromosome,mitotic cell cycle,presumptive embryonic/larval peripheral nervous system,mitotic domain & mitotic anaphase,chromosome,mesothoracic tergum" DRSC03539 I 2.387783831 0.299615719 0.443412305 1.163079801 0.028829645 -0.068903575 FBgn0001776 l(1)M55 lethal (1) M55 http://flybase.net/reports/FBgn0001776.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0036666 TSG101 Tumor susceptibility gene 101 http://flybase.net/reports/FBgn0036666.html FBgn0082594 protein_coding_gene "0005515=protein binding, 0043130=ubiquitin binding" "0036258=multivesicular body assembly, 0045571=negative regulation of imaginal disc growth, 0035090=maintenance of apical/basal cell polarity, 0015031=protein transport, 0045926=negative regulation of growth, 0060439=trachea morphogenesis, 0044130=negative regulation of growth of symbiont in host, 0006464=cellular protein modification process, 0046425=regulation of JAK-STAT cascade, 0060429=epithelium development, 0032509=endosome transport via multivesicular body sorting pathway, 0007293=germarium-derived egg chamber formation, 0007430=terminal branching, open tracheal system" 0000813=ESCRT I complex "CG9712, ESCRT-I, ept, DmTSG101, burs, tsg101, dTSg101, tumor suppressor protein 101, erupted, dTsg101, vps23, dVps23, Tsg1-1, Erupted, Ept, Tsg101, Tumor susceptibility gene 101 ortholog (H. sapiens), Tumor Susceptibility Gene-101" "IPR008883=Ubiquitin E2 variant, N-terminal, IPR017916=Steadiness box (SB) domain, IPR016135=Ubiquitin-conjugating enzyme/RWD-like" CG9712 16-Dec-15 2015_12 "ENSDARG00000011897(LOC100333057),ENSDARG00000040854(tsg101)" YCL008C(STP22) WBGene00015658(tsg-101) ENSMUSG00000014402(Tsg101) ENSG00000074319(TSG101) "lethal,recessive,partially lethal - majority die,hyperplasia,cell non-autonomous,somatic clone,large body,lethal - all die before end of pupal stage,some die during pupal stage,visible" "eye,somatic clone,head,eye-antennal disc,cell non-autonomous,eye photoreceptor cell,ommatidium,rhabdomere & eye photoreceptor cell | somatic clone,eye disc,oocyte,vesicle,yolk granule,epithelium,interfollicle cell,female germline cyst,wing,terminal tracheal cell,embryonic/larval tracheal system" FBgn0015838 Vang Van Gogh http://flybase.net/reports/FBgn0015838.html FBgn0020780 protein_coding_gene "0005109=frizzled binding, 0005515=protein binding" "0042067=establishment of ommatidial planar polarity, 0070593=dendrite self-avoidance, 0001736=establishment of planar polarity, 1902669=positive regulation of axon guidance, 0090175=regulation of establishment of planar polarity, 0045773=positive regulation of axon extension, 0007298=border follicle cell migration, 0007163=establishment or maintenance of cell polarity, 0001738=morphogenesis of a polarized epithelium" "0005886=plasma membrane, 0016021=integral component of membrane" "strabismus, Sltrabismus, vang/stbm, CG8075, vangogh/strabismus, Vang gogh, Stbm, Stb, stb, Vang-gogh, van-gogh, van gogh, VanGogh, vang, stbm/vang, Strabismus, Van Gogh/Strabismus, strabismus/Van Gogh, stbm, Vang/Stbm" IPR009539=Strabismus CG8075 16-Dec-15 2015_12 ENSDARG00000004305(vangl1) WBGene00015171(vang-1) ENSXETG00000005842(vangl2) "ENSMUSG00000027860(Vangl1),ENSMUSG00000026556(Vangl2)" "ENSG00000173218(VANGL1),ENSG00000162738(VANGL2)" " pupal stage | >24 hr , pupal stage | <24 hr , larval stage | third instar " " wing

, dorsal mesothoracic disc

" "visible,recessive,planar polarity defective,somatic clone,dominant,heat sensitive,semidominant,cell non-autonomous,viable,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially,cell polarity defective" "wing basal cell 1 & wing hair,wing,adult thorax,leg,adult abdomen,tarsal segment,ommatidium,somatic clone,eye photoreceptor cell,wing hair,thorax,pigment cell,abdomen,cell non-autonomous,dorsal wing blade,trichome & adult abdomen | somatic clone,trichome & adult abdomen | somatic clone | cell non-autonomous,embryo,maternal effect,eye,photoreceptor cell R3,photoreceptor cell R4,rhabdomere,cone cell,secondary pigment cell,tertiary pigment cell,macrochaeta & prothoracic segment,mesothoracic bristle,metathoracic bristle,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,trichome & adult thorax,trichome & adult head,tarsal segment 2,tarsal segment 3,tarsal segment 4,trichome,trichome & adult abdomen,trichome & pleural membrane,trichome & pleural membrane | somatic clone,trichome & pleural membrane | somatic clone | cell non-autonomous,wing cell,border follicle cell,polar follicle cell,trichome & adult abdomenë±Tub84B.PL,trichome & adult abdomen | somatic cloneë±Tub84B.PL,trichome & adult abdomen | somatic clone | cell non-autonomousë±Tub84B.PL,trichogen cell,supernumerary" FBgn0003339 Scr Sex combs reduced http://flybase.net/reports/FBgn0003339.html FBgn0002844 protein_coding_gene "0042803=protein homodimerization activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007381=specification of segmental identity, labial segment, 0045498=sex comb development, 0007432=salivary gland boundary specification, 0007379=segment specification, 0006357=regulation of transcription from RNA polymerase II promoter, 0007494=midgut development, 0007548=sex differentiation, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "CG1030, Sex Combs Reduced, l(3)84Af, Multiple sex comb, DmScr, scr, Msc, sex-combs reduced, sex combs reduced, BG:DS07876.2, Multi sex combs, SCR" "IPR001827=Homeobox protein, antennapedia type, conserved site, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR017995=Homeobox protein, antennapedia type, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG1030 16-Dec-15 2015_12 "ENSDARG00000013057(hoxb5a),ENSDARG00000054030(hoxb5b)" WBGene00003024(lin-39) ENSXETG00000000722(HOXA7) ENSG00000197576(HOXA4) " embryonic stage | 6.2-7.2 hr , embryonic stage | stage 11-17 , larval stage , embryonic stage , embryonic stage | >10.2-11.2 hr , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | 2.5-3.1 hr , embryonic stage | stage 9,10 , embryonic stage--pupal stage , embryonic stage | cellular blastoderm , embryonic stage | stage 14 " " ectoderm &&of embryonic labial segment

, embryonic labial segment

, labial disc

, embryonic brain

, ventral nerve cord | restricted

, ectoderm &&of embryonic prothoracic segment | restricted

, mesoderm &&of embryonic prothoracic segment

, embryonic central nervous system | restricted

, adepithelial cell of dorsal mesothoracic disc

, dorsal prothoracic disc

, embryonic myoblast &&of embryonic prothoracic segment

, adepithelial cell of ventral mesothoracic disc

, embryonic prothoracic segment

, parasegment 4 | anterior

{ + tsh-, Antp*, Df(3R)P9 } , ventral prothoracic disc

, embryonic central nervous system

, ventral mesothoracic disc | restricted

, labial segment

, cephalic furrow | posterior to

, ectoderm &&of parasegment 2

, prothoracic segment

, parasegment 3

{ + tsh-, Antp* } , embryonic subesophageal neuromere

, embryonic/larval pharynx

, parasegment 3

{ + tsh-, Antp*, Df(3R)P9 } , mesoderm &&of parasegment 3

, visceral mesoderm &&of anterior embryonic/larval midgut

, prothoracic segment &&of ectoderm | ventral

, parasegment 2

, dorsal mesothoracic disc | restricted

, subesophageal ganglion

, larval central nervous system

, embryonic nervous system

, parasegment 3

, visceral mesoderm &&of posterior embryonic/larval midgut

, parasegment 4 | anterior

" " embryonic stage , embryonic stage | stage 13-17 , embryonic stage | extended germ band , embryonic stage | >7.2 hr , embryonic stage | stage 11,12 , embryonic stage | stage 13-14 , embryonic stage | stage >13 , larval stage | third instar ,, embryonic stage | late extended germ band , larval stage , embryonic stage | stage 11-12 , embryonic stage | stage >14 , embryonic stage | stage 8 , embryonic stage | stage 6 , embryonic stage | stage 5 , embryonic stage | stage 13-15 , embryonic stage | stage 17 , embryonic stage | mid-late , embryonic stage | stage 12-14 , embryonic stage | >6.2-7.2 hr , adult stage , embryonic stage | stage 16 , embryonic stage | stage 13 " " posterior embryonic/larval midgut

, visceral mesoderm

, cephalic furrow | posterior to

, visceral mesoderm

{ - ftz*/prd* } , visceral mesoderm

{ 0 run* } , visceral mesoderm

{ v Antp- } , prothoracic segment

, labial segment

, visceral mesoderm &&of embryonic/larval midgut &&ofparasegment 4

, epidermis &&of prothoracic segment

, labial disc

, parasegment 4 visceral mesoderm

{ $ ftz* } , visceral mesoderm

{ - opa* } , ectoderm &&of embryonic prothoracic segment

, visceral mesoderm

{ $ kni* } , ventral thoracic disc

{ - Pc3/brm2 } , prothoracic segment &&of ectoderm

, visceral mesoderm &&of anterior embryonic/larval midgut

, ventral thoracic disc

, parasegment 3

, visceral mesoderm

{ 0 en* } , visceral mesoderm

{ $ eve4 } , embryonic/larval salivary gland

, subesophageal ganglion

, visceral mesoderm &&of posterior embryonic/larval midgut

, visceral mesoderm

{ - eve3 } , embryonic labial segment &&of ectoderm

, parasegment 2--4

, visceral mesoderm

{ - opa*/prd* } , ectoderm | restricted

, embryonic subesophageal neuromere

, parasegment 2 &&of ectoderm

, ventral nerve cord | restricted

, visceral mesoderm

{ 0 odd* } , hypostomal sclerite | ventral to

, parasegment 3 &&of embryonic central nervous system

, epidermis &&of labial segment

, maxillary segment | posterior

, gastric caecum

, dorsal ridge

, visceral mesoderm

{ 0 prd* } , parasegment 2

, visceral mesoderm

{ $ Kr* } , prothoracic segment | anterior

, visceral mesoderm

{ 0 wg* } , visceral mesoderm

{ 0 h* } , ectoderm &&of embryonic labial segment

, visceral mesoderm

{ - hb* } , parasegment 2 &&of embryonic central nervous system

, visceral mesoderm

{ 0 odd*/eve* } , ventral prothoracic disc

, dorsal thoracic disc

, embryonic central nervous system | restricted

, parasegment 2,3 &&of embryonic central nervous system

, prothoracic segment | lateral

" "visible,dominant,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,homeotic,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,polyphasic,viable,somatic clone,cold sensitive,partially,wild-type,some die during pupal stage" "sex comb,pseudotrachea,metathoracic leg,male,ectopic,mesothoracic leg,prothoracic leg,mesothoracic leg & sex comb | ectopic,metathoracic leg & sex comb | ectopic,mesothoracic leg & sex comb | ectopic | conditional ts,T1 beard,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic thoracic segment,embryonic head,embryonic/larval salivary gland,supernumerary,third segment of antenna,arista,tarsal segment,eye,mesothoracic leg & sex comb | ectopic, with Dp(3;Y)77ab,metathoracic leg & sex comb | ectopic, with Dp(3;Y)77ab,antenna,adult salivary gland primordium,heat sensitive,larval mesothoracic segment,larval metathoracic segment,adult head,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,cephalopharyngeal skeleton,maxillary palpus,labellum,occiput,larval head,dorsal closure embryo,prothoracic segment,adult labial segment,labial segment,salivary gland imaginal ring,proboscis,pronotum,somatic clone,sex comb tooth,labial disc,embryonic/larval labial organ,haltere,metathoracic laterotergite,wing,scutum,embryonic prothoracic segment,embryonic labial segment,presumptive embryonic/larval peripheral nervous system,distal,mesothoracic leg & sex comb | ectopic77ab), with Df(3R)Scr,metathoracic leg & sex comb | ectopic77ab), with Df(3R)Scr,cell autonomous,sternopleural bristle,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,cold sensitive,salivary gland,metathoracic tarsal bristle transverse row,prothoracic tarsal segment,mesothoracic tarsal segment,metathoracic tarsal segment,pretarsus,prothoracic ventral intersegmental muscle,metathoracic ventral acute muscle,embryonic/larval midgut primordium,embryonic gastric caecum & parasegment 3how-24B,embryonic gastric caecum & parasegment 7how-24B,midgut chamber 2,gastric caecum primordium,embryonic tritocerebrum,mesothoracic tergum" FBgn0020386 Pdk1 Phosphoinositide-dependent kinase 1 http://flybase.net/reports/FBgn0020386.html FBgn0035098 protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0045793=positive regulation of cell size, 0051124=synaptic growth at neuromuscular junction, 0007476=imaginal disc-derived wing morphogenesis, 0045471=response to ethanol, 0046620=regulation of organ growth, 0030307=positive regulation of cell growth, 0001558=regulation of cell growth, 0008286=insulin receptor signaling pathway, 0040018=positive regulation of multicellular organism growth, 0007548=sex differentiation, 0006468=protein phosphorylation, 0048477=oogenesis, 0006974=cellular response to DNA damage stimulus, 0043066=negative regulation of apoptotic process, 0007283=spermatogenesis, 0007166=cell surface receptor signaling pathway" "0031594=neuromuscular junction, 0005886=plasma membrane, 0005737=cytoplasm, 0005829=cytosol" "DSTPK61, PK61C, PDK-1, dPDK, Phosphoinositide dependent kinase 1, PDK1, PDK, pdk1, 1210, phosphoinositide-dependent kinase 1, Pk61C, Pk61c/PDK1, Pk61C|PDK1, serine/threonine protein kinase, pk61c, CG1201, CG1210, Dstpk61, dPDK1, Pk61C/PDK1, dSTPK61, Protein kinase 61C, dPDK-1, Pdk1, PDK1/Pk61C, protein kinase 61C" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR008271=Serine/threonine-protein kinase, active site" CG1210 16-Dec-15 2015_12 "ENSDARG00000062304(pdpk1a),ENSDARG00000018285(pdpk1b)" WBGene00003965(pdk-1) ENSXETG00000004025() "partially lethal - majority die,small body,neuroanatomy defective,lethal,recessive,chemical resistant,male limited,viable,male sterile,developmental rate defective,decreased cell size,somatic clone,cell autonomous,visible,increased cell size,chemical sensitive,increased cell death,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "motor neuron,NMJ bouton,embryonic/larval neuromuscular junction,supernumerary | third instar larval stage,macrochaeta,eye,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,adult head,wing disc,somatic clone,wing,embryonic/larval neuroblast,ommatidium,germline cell,male,embryonic ventral epidermis" DRSC08682 IEK -0.829272514 2.353649497 -1.292842261 -1.88418029 0.232151716 1.806230039 FBgn0004650 fs(1)N female sterile (1) Nasrat http://flybase.net/reports/FBgn0004650.html "FBgn0000750, FBgn0000914, FBgn0024367" protein_coding_gene "0008595=anterior/posterior axis specification, embryo, 0048477=oogenesis, 0007306=eggshell chorion assembly, 0007362=terminal region determination, 0007304=chorion-containing eggshell formation, 0007305=vitelline membrane formation involved in chorion-containing eggshell formation" "0005737=cytoplasm, 0005576=extracellular region, 0009897=external side of plasma membrane, 0060388=vitelline envelope, 0045172=germline ring canal" "Fs(1)N, fs(1)Nasrat, CG11411, nas, Nas, EG:8D8.1, fs(1)[nas], unnamed, Nasrat, fs(1)K1540, 8D8.1, 371, fs(1)M6, fs(1)Nas, fs(1)A371" CG11411 16-Dec-15 2015_12 "female sterile,neuroanatomy defective,female sterile soma-dependent,recessive,terminal phenotype,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,wild-type,heat sensitive,female sterile germline-dependent,viable" "vitelline membrane,intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse,egg,cephalopharyngeal skeleton,maternal effect,head,anterior,telson,abdominal segment 8,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,labrum,ocular segment,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic telson,proctodeum,wing vein L2,wing vein L3,oocyte" FBgn0000327 clv-1 cloven thorax 1 http://flybase.net/reports/FBgn0000327.html gene 16-Dec-15 2015_12 "visible,dominant,partially lethal - majority die,cold sensitive" adult thorax FBgn0010562 l(2)03996 lethal (2) 03996 http://flybase.net/reports/FBgn0010562.html gene 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0003660 Syb Synaptobrevin http://flybase.net/reports/FBgn0003660.html "FBgn0005620, FBgn0019711, FBgn0023032" protein_coding_gene 0005484=SNAP receptor activity "0035149=lumen formation, open tracheal system, 0007269=neurotransmitter secretion, 0048489=synaptic vesicle transport, 0016192=vesicle-mediated transport, 0016081=synaptic vesicle docking" "0008021=synaptic vesicle, 0016021=integral component of membrane, 0005886=plasma membrane, 0031201=SNARE complex" "l(2)46El, VAMP, 21.15, VAMP2, l(2)46CFq, SYB, Vamp, J, synaptobrevin, syb, dVAMP, Vesicle-associated membrane protein, CG12210, END1-2, Complementation group J, VAMP3, unnamed, c-Syb" IPR001388=Synaptobrevin CG12210 16-Dec-15 2015_12 "ENSDARG00000056877(vamp2),ENSDARG00000070137,ENSDARG00000070161(vamp3)" "YAL030W(SNC1),YOR327C(SNC2)" WBGene00004897(snb-1) ENSXETG00000025515(vamp3) " adult stage , embryonic stage | stage 13 , embryonic stage | early , embryonic stage -- adult stage , embryonic stage | extended germ band , embryonic stage | contracted germ band " " pupal/adult digestive system

, Malpighian tubule primordium

, adult head

, inclusive hindgut primordium

, posterior midgut proper primordium

, anterior midgut proper primordium

, stomodeum

" "lethal,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,ommatidium,embryonic/larval tracheal system" FBgn0024754 Flo1 Flotillin 1 http://flybase.net/reports/FBgn0024754.html protein_coding_gene 0005198=structural molecule activity "0005886=plasma membrane, 0016600=flotillin complex, 0005737=cytoplasm" "flo, FLO[Dm]-1, flotillin-1, Flotillin1, flotillin, flo1, Flo1, FLO1, Flo[Dm], Flotillin, CG8200, reggie2, Flo-1, Flotillin-1, CK02126, Flo, FLO[Dm], reggie-2" "IPR001107=Band 7 protein, IPR027705=Flotillin family" CG8200 16-Dec-15 2015_12 "ENSDARG00000037998(flot1b),ENSDARG00000001710(flot1)" ENSXETG00000024085(FLOT1) ENSMUSG00000059714(Flot1) "ENSG00000137312(FLOT1),ENSG00000206480,ENSG00000206379" embryonic stage | stage >=12 " ventral nerve cord

, embryonic brain

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC28122 K -0.388800432 -0.179426376 -0.03545058 0.459484138 -2.492884144 -0.178372016 FBgn0250788 ë_-Spec ë_ Spectrin http://flybase.net/reports/FBgn0250788.html "FBgn0027278, FBgn0026686, FBgn0026676, FBgn0025269, FBgn0003471, FBgn0026229" protein_coding_gene "0030506=ankyrin binding, 0003779=actin binding, 0008017=microtubule binding, 0005516=calmodulin binding, 0008092=cytoskeletal protein binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding, 0005200=structural constituent of cytoskeleton, 0051015=actin filament binding" "0007399=nervous system development, 0007026=negative regulation of microtubule depolymerization, 0007409=axonogenesis, 0072499=photoreceptor cell axon guidance, 0045478=fusome organization, 0007274=neuromuscular synaptic transmission, 0007009=plasma membrane organization, 0007411=axon guidance, 0050807=regulation of synapse organization, 0030721=spectrosome organization, 0048790=maintenance of presynaptic active zone structure, 0016199=axon midline choice point recognition, 0042062=long-term strengthening of neuromuscular junction" "0016327=apicolateral plasma membrane, 0005811=lipid particle, 0016328=lateral plasma membrane, 0031594=neuromuscular junction, 0008091=spectrin, 0045170=spectrosome, 0045169=fusome, 0005886=plasma membrane, 0030424=axon" "kus, Specbeta, betaspec, beta-spec, l(1)G0198, Spec, l(1)G0074, karussell, SPEC8, spectrin, i6, Spectrin, Spec-beta, anon-fast-evolving-1B3, betaSpec, i168, CG5870, b-Spec, beta-Spec, b spectrin, beta-spectrin, beta Spectrin, anon-EST:fe1B3, l(1)G0108, beta, beta-Spectrin, beta spectrin, B-spec, Beta-spectrin" "IPR002017=Spectrin repeat, IPR001589=Actinin-type actin-binding domain, conserved site, IPR016343=Spectrin, beta subunit, IPR018159=Spectrin/alpha-actinin, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001715=Calponin homology domain, IPR001605=Pleckstrin homology domain, spectrin-type, IPR001849=Pleckstrin homology domain" CG5870 16-Dec-15 2015_12 "ENSDARG00000036402,ENSDARG00000053956(LOC558044),ENSDARG00000030490(sptb)" WBGene00006803(unc-70) ENSXETG00000002566(SPTBN4) "ENSMUSG00000020315(Spnb2),ENSMUSG00000067889(Spnb3),ENSMUSG00000021061(Spnb1)" "ENSG00000115306(SPTBN1),ENSG00000173898(SPTBN2),ENSG00000070182(SPTB)" " embryonic stage , embryonic stage | stage 10 " " larval visceral muscle

, embryonic/larval trachea

, mesoderm

, epidermis

, inclusive hindgut primordium

, embryonic/larval foregut | precursor

, embryonic/larval somatic muscle

" " embryonic stage | early , adult stage && oogenesis stage , embryonic stage | mid & late , embryonic stage | mid , embryonic stage | mid-late , adult stage && oogenesis stage | early , embryonic stage | late " " amnioproctodeal invagination

, follicle cell

, ventral furrow

, embryonic/larval somatic muscle

, ventral midline

, embryonic/larval hindgut

, embryonic/larval trachea

, spectrosome &&of germarium

, epidermis

, larval visceral muscle

, fusome &&of germarium

, pharyngeal muscle

, cephalic furrow

, embryonic/larval salivary gland

, embryonic/larval esophagus

, amnioserosa

" FBgn0053892 His2B:CG33892 His2B:CG33892 http://flybase.net/reports/FBgn0053892.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome "His2b:CG33892, CG33892" "IPR000558=Histone H2B, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33892 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0020865 cass cassowary http://flybase.net/reports/FBgn0020865.html gene "0048598=embryonic morphogenesis, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces" "cas, bladderwrack, bad" 16-Dec-15 2015_12 "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" "wing,somatic clone,embryonic/first instar larval cuticle,dorsal,embryonic/larval somatic muscle" FBgn0028315 l(1)G0356 lethal (1) G0356 http://flybase.net/reports/FBgn0028315.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" adult abdomen FBgn0264664 steeple steeple http://flybase.net/reports/FBgn0264664.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0034744 Vps20 Vacuolar protein sorting 20 http://flybase.net/reports/FBgn0034744.html FBgn0027684 protein_coding_gene "0007034=vacuolar transport, 0050680=negative regulation of epithelial cell proliferation, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0030713=ovarian follicle cell stalk formation, 0008593=regulation of Notch signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0032509=endosome transport via multivesicular body sorting pathway" 0000815=ESCRT III complex "anon-EST:Posey40, ESCRT-III, vps20, Vps20, DmVPS20, CG4071" IPR005024=Snf7 family CG4071 16-Dec-15 2015_12 "ENSDARG00000070978(LOC100147988),ENSDARG00000021202(chmp6l)" YMR077C(VPS20) WBGene00022027(vps-20) ENSXETG00000013409(CHMP6) ENSMUSG00000025371(Chmp6) ENSG00000176108(CHMP6) "increased cell number,lethal,partially lethal - majority die,visible" "eye,somatic clone,epithelium,interfollicle cell,female germline cyst,trichogen cell,mesothoracic tergum" FBgn0036007 path pathetic http://flybase.net/reports/FBgn0036007.html "FBgn0062062, FBgn0062128" protein_coding_gene 0015171=amino acid transmembrane transporter activity "0040007=growth, 0048813=dendrite morphogenesis, 0040008=regulation of growth, 0032536=regulation of cell projection size, 0044719=regulation of imaginal disc-derived wing size, 0097484=dendrite extension, 0003333=amino acid transmembrane transport" "0043025=neuronal cell body, 0005886=plasma membrane, 0030425=dendrite, 0030424=axon, 0036019=endolysosome" "CG3424, anon-WO0118547.370, pth, Pathetic, anon-WO0118547.271, Path" "IPR013057=Amino acid transporter, transmembrane domain" CG3424 16-Dec-15 2015_12 ENSDARG00000039661 "YNL101W(AVT4),YKL146W(AVT3)" "WBGene00012804(Y43F4B.7),WBGene00020837(T27A1.5)" "small body,decreased cell number,decreased cell size,developmental rate defective,eclosion rhythm defective,female sterile,increased cell size,increased cell number,viable,size defective" "wing,ommatidium,adult salivary gland,adult fat body,eye,posterior" FBgn0061001 l(3)S026821 lethal (3) S026821 http://flybase.net/reports/FBgn0061001.html gene 0268/21 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0016078 wun wunen http://flybase.net/reports/FBgn0016078.html FBgn0017369 protein_coding_gene "0016791=phosphatase activity, 0008195=phosphatidate phosphatase activity, 0042803=protein homodimerization activity" "0009880=embryonic pattern specification, 0035233=germ cell repulsion, 0007280=pole cell migration, 0019991=septate junction assembly, 0035234=ectopic germ cell programmed cell death, 0007424=open tracheal system development, 0050829=defense response to Gram-negative bacterium, 0008354=germ cell migration, 0045824=negative regulation of innate immune response, 0016311=dephosphorylation" "0005886=plasma membrane, 0016020=membrane, 0016021=integral component of membrane, 0005918=septate junction, 0045177=apical part of cell" "LPP-like, CG8804, l(2)k16806, Wun, Wunen" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG8804 16-Dec-15 2015_12 "ENSDARG00000059933(si:dkey-19f4.1),ENSDARG00000069940(zgc:158309),ENSDARG00000002231(LOC563806),ENSDARG00000028896(zgc:66434)" WBGene00018756(F53C3.13) "ENSXETG00000011144(ppap2b),ENSXETG00000000375(ppap2a),ENSXETG00000026886(ppap2c)" "ENSMUSG00000028517(Ppap2b),ENSMUSG00000021759(Ppap2a),ENSMUSG00000052151(Ppap2c)" "ENSG00000067113(PPAP2A),ENSG00000141934(PPAP2C),ENSG00000162407(PPAP2B)" " embryonic stage | late , embryonic stage " " embryonic central nervous system

, ectoderm | restricted

, posterior midgut proper primordium | dorsal

, inclusive hindgut primordium

" "learning defective,viable,fertile,lethal,recessive,neuroanatomy defective,wild-type,female sterile,partially lethal - majority die" "embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval transverse connective,germline cell,female,male,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,embryonic proventriculus,presumptive embryonic/larval digestive system,synapse,bouton" FBgn0001959 l(2)34Db lethal (2) 34Db http://flybase.net/reports/FBgn0001959.html gene "l(2)br20, l(2)br21, l(2)br18, lethal 21 in the black-reduced region, 34Db, lethal 18 in the black-reduced region, l(2)06311, l34Db, lethal 20 in the black-reduced region, br20" 16-Dec-15 2015_12 "lethal,recessive,female sterile,male sterile,visible" "eye,ocellar bristle,posterior scutellar bristle,macrochaeta,wing" FBgn0003882 tub tube http://flybase.net/reports/FBgn0003882.html "FBan0010520, FBgn0015226" protein_coding_gene "0019904=protein domain specific binding, 0005515=protein binding" "0007352=zygotic specification of dorsal/ventral axis, 0019732=antifungal humoral response, 0006952=defense response, 0009620=response to fungus, 0030097=hemopoiesis, 0035172=hemocyte proliferation, 0048262=determination of dorsal/ventral asymmetry, 0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway" "0005886=plasma membrane, 0005737=cytoplasm, 0005829=cytosol" "Tube, TUBE, CG10520" "IPR029397=Tube Death domain, IPR011029=Death-like domain, IPR000488=Death domain" CG10520 16-Dec-15 2015_12 " embryonic stage -- adult stage , adult stage && oogenesis stage " oocyte

"viable,fertile,lethal,maternal effect,dorsal/ventral axis specification defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,cold sensitive,heat sensitive" "embryonic/first instar larval cuticle,hemocyte,embryonic/larval hemolymph,embryonic/larval hemocyte,embryonic/larval somatic muscle,segment border muscle,epidermis" DRSC22800 EK -1.214803202 0.694340053 -1.777558022 1.236314012 1.876121648 -0.064118413 FBgn0031759 lid little imaginal discs http://flybase.net/reports/FBgn0031759.html FBgn0010658 protein_coding_gene "0034647=histone demethylase activity (H3-trimethyl-K4 specific), 0032453=histone demethylase activity (H3-K4 specific), 0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, 0008270=zinc ion binding, 0005515=protein binding, 0043992=histone acetyltransferase activity (H3-K9 specific), 0003677=DNA binding" "0043970=histone H3-K9 acetylation, 0034720=histone H3-K4 demethylation, 0006325=chromatin organization, 0007526=larval somatic muscle development, 0055114=oxidation-reduction process, 0045475=locomotor rhythm" "0005634=nucleus, 0070822=Sin3-type complex" "KDM5, l(2)10424, LID, dKDM5/LID, Little imaginal discs, dJARID1, Lid, CG9088, little imaginal disks" "IPR001965=Zinc finger, PHD-type, IPR001606=ARID DNA-binding domain, IPR003347=JmjC domain, IPR019787=Zinc finger, PHD-finger, IPR004198=Zinc finger, C5HC2-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR003349=JmjN domain, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR013637=Lysine-specific demethylase-like domain" CG9088 16-Dec-15 2015_12 "ENSDARG00000057093(kdm5ba),ENSDARG00000003098(kdm5bb),ENSDARG00000006124(kdm5c)" "YDR096W(GIS1),YER169W(RPH1)" WBGene00004319(rbr-2) "ENSXETG00000007973(KDM5B),ENSXETG00000003642(KDM5A),ENSXETG00000007178()" "ENSMUSG00000042207(Kdm5b),ENSMUSG00000030180(Kdm5a),ENSMUSG00000025332(Kdm5c),ENSMUSG00000056673(Kdm5d)" "ENSG00000073614(KDM5A),ENSG00000117139(KDM5B),ENSG00000012817(KDM5D),ENSG00000126012(KDM5C)" "viable,female sterile,short lived,male,chemical sensitive,lethal,partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,dominant,locomotor rhythm defective,visible" "imaginal disc,embryonic/larval optic lobe,macrochaeta,supernumerary,mesothoracic tergum" FBgn0263979 Caf1-55 "Chromatin assembly factor 1, p55 subunit" http://flybase.net/reports/FBgn0263979.html "FBgn0025477, FBgn0016688, FBgn0015610, FBgn0263347, FBgn0086202" protein_coding_gene "0042803=protein homodimerization activity, 0005515=protein binding, 0042393=histone binding, 0042826=histone deacetylase binding, 0046976=histone methyltransferase activity (H3-K27 specific), 0035035=histone acetyltransferase binding, 0042054=histone methyltransferase activity, 0070615=nucleosome-dependent ATPase activity, 0003682=chromatin binding, 0031491=nucleosome binding, 0046974=histone methyltransferase activity (H3-K9 specific)" "0042766=nucleosome mobilization, 0016571=histone methylation, 0006342=chromatin silencing, 0016573=histone acetylation, 0007307=eggshell chorion gene amplification, 0006334=nucleosome assembly, 0006281=DNA repair, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048666=neuron development, 0006335=DNA replication-dependent nucleosome assembly, 0007379=segment specification, 0061085=regulation of histone H3-K27 methylation, 0048813=dendrite morphogenesis, 0016584=nucleosome positioning, 0031497=chromatin assembly, 0007346=regulation of mitotic cell cycle, 0000281=mitotic cytokinesis, 0007517=muscle organ development, 0048812=neuron projection morphogenesis, 0006351=transcription, DNA-templated, 0008284=positive regulation of cell proliferation" "0005667=transcription factor complex, 0005700=polytene chromosome, 0035098=ESC/E(Z) complex, 0033186=CAF-1 complex, 0016581=NuRD complex, 0070822=Sin3-type complex, 0016589=NURF complex, 0016590=ACF complex, 0031523=Myb complex, 0005634=nucleus, 0035097=histone methyltransferase complex" "CAF-1, CAF1-p55, RbAp48, 154659_at, p55CAF1, NURF55, chromatin assembly factor 1, Chromatin associated factor-1 subunit, CAF1-55, dCAF-1, MSI1/RbAp48/CAC3/LIN-53, NURF 55, Nurf, p55 CAF1, RbAp46/48, Chromatin Assembly Factor 1, Chromatin assembly factor 1, caf-1, Chromatin Assembly Factor-1, NURF-55, 55, Chromatin assembly factor 1 subunit, d-CAF1, Caf1/p55, dCAF1-p55, NURF, unnamed, Nurf55/CAF1, dCAF-1 p55, p55/NURF-55, Caf1p55, p55, Nurf 55, Nurf55, caf1 p55, Caf-1, RBAP48, Nucleosome remodeling factor, Nucleosome remodeling factor - 55kD, CAF1, Nurf-55, dNURF, dCAF1, Caf1, p55,CAF1, S(ls)3, caf1, CAF1p55, P55, dCAF-1-p55, CG4236" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR022052=Histone-binding protein RBBP4, N-terminal, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG4236 16-Dec-15 2015_12 "ENSDARG00000015208(rbb4l),ENSDARG00000029058(rbb4)" YEL056W(HAT2) WBGene00003036(lin-53) ENSXETG00000026983(rbbp7) ENSMUSG00000057236(Rbbp4) ENSG00000162521(RBBP4) embryonic stage--larval stage DRSC16596 I -2.289954258 -2.716505732 -0.339223968 -0.625909046 0.093045386 0.100834671 FBgn0002566 lt light http://flybase.net/reports/FBgn0002566.html "FBan0018028, FBgn0032992" protein_coding_gene 0008270=zinc ion binding "0046907=intracellular transport, 0006727=ommochrome biosynthetic process, 0007033=vacuole organization, 0000046=autophagic vacuole fusion, 0008340=determination of adult lifespan, 0009267=cellular response to starvation, 0035542=regulation of SNARE complex assembly, 0045746=negative regulation of Notch signaling pathway, 0006726=eye pigment biosynthetic process, 0007041=lysosomal transport, 0033227=dsRNA transport, 0007220=Notch receptor processing, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0006897=endocytosis" 0030897=HOPS complex "Lt, vps41, pinkoid, Vps41, Dm-lt(het), CG18028, pink-wing, l(2)40Fb" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR016024=Armadillo-type fold, IPR016902=Vacuolar protein sorting-associated protein 41, IPR017986=WD40-repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR000547=Clathrin, heavy chain/VPS, 7-fold repeat, IPR001841=Zinc finger, RING-type, IPR001680=WD40 repeat" CG18028 16-Dec-15 2015_12 ENSDARG00000063573(si:ch211-146l10.2) YDR080W(VPS41) WBGene00017974(vps-41) ENSXETG00000016782(VPS41) ENSMUSG00000041236(Vps41) ENSG00000006715(VPS41) " larval stage , larval stage | third instar , egg stage | unfertilized egg , embryonic stage -- adult stage , embryonic stage , adult stage | female " " embryonic/larval fat body

, larval brain

, unfertilized egg | ubiquitous

, Malpighian tubule

, larval digestive system

, embryonic/larval circulatory system

, unfertilized egg

,

ubiquitous , imaginal disc

, gonad

, ovary

, larval salivary gland

" "wild-type,short lived,male,eye color defective,lethal,partially,recessive,viable,dominant,lethal - all die before end of pupal stage,some die during pupal stage,visible,enhancer of variegation,suppressor of variegation,sterile" "ocellus pigment granule,pigment cell,embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditionallt45),autophagic vacuole | supernumerary | wandering third instar larval stage | nutrition conditionallt45),Malpighian tubule,wing,eye,somatic clone,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0030985 Obp18a Odorant-binding protein 18a http://flybase.net/reports/FBgn0030985.html FBgn0062952 protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "obp18a, 18a, DmelObp18a, BcDNA:RH25665, CG15883" IPR006170=Pheromone/general odorant binding protein CG15883 16-Dec-15 2015_12 viable FBgn0027283 l(1)G0179 lethal (1) G0179 http://flybase.net/reports/FBgn0027283.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0020626 Osbp Oxysterol binding protein http://flybase.net/reports/FBgn0020626.html protein_coding_gene 0008142=oxysterol binding "0006886=intracellular protein transport, 0007030=Golgi organization, 0007291=sperm individualization" "0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "oxysterol binding protein, Oxysterol Binding Protein, OSBP-Dm, CG6708, osbp, oxysterol-binding protein" "IPR001849=Pleckstrin homology domain, IPR018494=Oxysterol-binding protein, conserved site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000648=Oxysterol-binding protein" CG6708 16-Dec-15 2015_12 "ENSDARG00000022772(si:ch211-106a19.1),ENSDARG00000053487(LOC794414),ENSDARG00000004634(si:ch211-149g8.3),ENSDARG00000020098" "YDL019C(OSH2),YAR042W(SWH1)" WBGene00012930(obr-1) ENSXETG00000020714(OSBP) "ENSMUSG00000024687(Osbp),ENSMUSG00000020435(Osbp2)" "ENSG00000110048(OSBP),ENSG00000184792(OSBP2)" "visible,viable,male semi-sterile,male sterile" "wing,adult thorax,adult cuticle,Golgi apparatusCCAP.PP,individualization stage spermatid" FBgn0264654 missing-parts missing parts http://flybase.net/reports/FBgn0264654.html gene 0060439=trachea morphogenesis 16-Dec-15 2015_12 neuroanatomy defective "embryonic/larval dorsal trunk,terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0037379 CG10979 http://flybase.net/reports/FBgn0037379.html protein_coding_gene 0046872=metal ion binding 0022008=neurogenesis "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG10979 16-Dec-15 2015_12 "ENSDARG00000070501,ENSDARG00000004594,ENSDARG00000039843(zgc:63570)" ENSG00000048405(ZNF800) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum" FBgn0028513 CG9254 http://flybase.net/reports/FBgn0028513.html protein_coding_gene 0005436=sodium:phosphate symporter activity 0055085=transmembrane transport 0016021=integral component of membrane "BG:DS07660.1, DS07660.1" "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG9254 16-Dec-15 2015_12 "YOR378W(),YML116W(ATR1),YMR279C()" viable FBgn0031260 Spp Signal peptide peptidase http://flybase.net/reports/FBgn0031260.html protein_coding_gene "0042500=aspartic endopeptidase activity, intramembrane cleaving" "0006465=signal peptide processing, 0034620=cellular response to unfolded protein, 0007424=open tracheal system development" "0016020=membrane, 0016021=integral component of membrane, 0005783=endoplasmic reticulum" "signal peptide peptidase, shanti, spp, CG11840, DmSPP, Signal Peptide Peptidase, SPP, Signal peptide protease" "IPR006639=Presenilin/signal peptide peptidase, IPR007369=Peptidase A22B, signal peptide peptidase" CG11840 16-Dec-15 2015_12 ENSDARG00000037846(hm13) YKL100C() WBGene00011481(imp-2) ENSXETG00000024014(HM13) ENSMUSG00000019188(H13) ENSG00000101294(HM13) "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,viable" "heart primordium,embryonic/larval tracheal system,wing,posterior compartment,trichogen cell" FBgn0040158 l(1)G0451 lethal (1) G0451 http://flybase.net/reports/FBgn0040158.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263885 l(3)B27 http://flybase.net/reports/FBgn0263885.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0032196 CG5708 http://flybase.net/reports/FBgn0032196.html protein_coding_gene 0008270=zinc ion binding "IPR001781=Zinc finger, LIM-type" CG5708 16-Dec-15 2015_12 "ENSDARG00000054749(lmo4b),ENSDARG00000013853(lmo4a),ENSDARG00000052657,ENSDARG00000015849(zgc:56628)" "ENSXETG00000023465(lmo4l),ENSXETG00000023295(lmo4)" ENSMUSG00000028266(Lmo4) ENSG00000143013(LMO4) viable FBgn0004859 ci cubitus interruptus http://flybase.net/reports/FBgn0004859.html "FBgn0000314, FBgn0000315, FBgn0010154, FBgn0010155, FBgn0017411, FBgn0019831" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0044212=transcription regulatory region DNA binding, 0046872=metal ion binding, 0005515=protein binding, 0042803=protein homodimerization activity, 0001205=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0030858=positive regulation of epithelial cell differentiation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035277=spiracle morphogenesis, open tracheal system, 0035017=cuticle pattern formation, 0007346=regulation of mitotic cell cycle, 1900087=positive regulation of G1/S transition of mitotic cell cycle, 0048100=wing disc anterior/posterior pattern formation, 0048477=oogenesis, 0007224=smoothened signaling pathway, 0007367=segment polarity determination, 0035217=labial disc development, 0002385=mucosal immune response, 0035224=genital disc anterior/posterior pattern formation, 0060914=heart formation, 0048666=neuron development, 0048813=dendrite morphogenesis, 0008544=epidermis development, 0007350=blastoderm segmentation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0030707=ovarian follicle cell development, 0006355=regulation of transcription, DNA-templated, 0048592=eye morphogenesis" "0005737=cytoplasm, 0043234=protein complex, 0035301=Hedgehog signaling complex, 0005634=nucleus, 0016020=membrane" "Ci/Gli, l(4)102ABc, Ci155, ciD, CG2125, Siah, CID, ci155, Cubitus interuptus, Ci[D], cubitus-interruptus-dominant, Cell, cubitus-interruptus-Dominant, CI, ci[D], Cubitus Interruptus, l(4)13, Ci, l(4)17, Ci/GLI, cubitus-interruptus, ci-D, Cubitus-interruptus, cubitus interuptus, Cubitis Interruptus, CiD, Gli, cubitis interruptus, Cubitus Interuptus, Cubitus interruptus, Ce" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG2125 16-Dec-15 2015_12 "ENSDARG00000025641(gli2a),ENSDARG00000020884,ENSDARG00000052131(gli3),ENSDARG00000033680" "ENSXETG00000001856(GLI3),ENSXETG00000011189(GLI2),ENSXETG00000017144(GLI1)" "ENSMUSG00000021318(Gli3),ENSMUSG00000048402(Gli2)" "ENSG00000106571(GLI3),ENSG00000074047(GLI2)" " embryonic stage , embryonic stage | cellular blastoderm , embryonic stage | gastrula , embryonic stage | stage 7 , larval stage , embryonic stage | extended germ band " " mesectoderm

, embryonic central nervous system

,

ubiquitous ,

, embryonic/larval hindgut

, segment

, ectoderm

,

segment polarity , imaginal disc | anterior

, embryonic/larval foregut

, ectoderm | striped

, mesoderm

" larval stage | third instar " dorsal mesothoracic disc | anterior compartment & proximal to anterior/posterior compartment boundary

, male genital disc | restricted

, female genital disc | restricted

" "visible,neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,cold sensitive,lethal - all die before end of pupal stage,some die during pupal stage,viable,somatic clone,mitotic cell cycle defective,cell autonomous,sterile,wild-type,segment polarity phenotype,partially,homeotic" "eye,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,dorsal multidendritic neuron ddaD,wing vein,embryonic epidermis,wing vein L4,wing vein L5,embryonic/first instar larval cuticle,leg,wing,ommatidial precursor cluster,anterior compartment,ventral thoracic disc,wing disc,antenna,ommatidium,somatic clone,wing blade,wing vein L2,wing vein L3,ectopic,wing vein L4 & sensillum campaniformium | ectopic | somatic clone,wing vein L4 & wing sensillum | ectopic | somatic clone,denticle belt,denticle,denticle row 2,denticle row 3,denticle row 4,follicle stem cell,anterior,ventral,denticle row 1,supernumerary,eye disc,cell autonomous,prothoracic ventral denticle belt,ocellus,ocellar bristle,scutellar bristle,postvertical bristle,Bolwig organ,denticle row 5,denticle row 6,embryo,posterior compartment,embryonic/larval dorsal vessel,mesothoracic tarsal bristle longitudinal row 1,wing margin bristle,alula,wing margin,posterior,keyhole structure,trichome of the posterior wing margin,cold sensitive,interfollicle cell,interommatidial bristle,retina,lamina,lamina & neuron | precursorë±Tub84B.PP,1st posterior cell,thorax,head capsule,dorsal,embryonic/larval dorsal branch,egg chamber,germarium,morphogenetic furrow,tracheal tip cell | embryonic stage,filzkorper,stigmatophore,larval thoracic segment,larval abdominal segment,pseudotrachea,anal plate,adult hindgut,proximal,S phase | ectopic | somatic clone,S phase | ectopicbbg-C96,sensory mother cell,anterior crossvein,distal,glial cell & eye disc | somatic clone,dorsal branch primordium" FBgn0040290 RecQ4 RecQ4 helicase http://flybase.net/reports/FBgn0040290.html FBgn0035846 protein_coding_gene "0005524=ATP binding, 0003697=single-stranded DNA binding, 0008270=zinc ion binding, 0043140=ATP-dependent 3'-5' DNA helicase activity, 0003678=DNA helicase activity, 0004386=helicase activity, 0008094=DNA-dependent ATPase activity" "0045740=positive regulation of DNA replication, 0002164=larval development, 0006302=double-strand break repair, 0006284=base-excision repair, 0006260=DNA replication, 0036292=DNA rewinding, 0006281=DNA repair, 0007307=eggshell chorion gene amplification, 0032508=DNA duplex unwinding, 0008284=positive regulation of cell proliferation, 0051301=cell division, 0010971=positive regulation of G2/M transition of mitotic cell cycle, 0048477=oogenesis, 0007095=mitotic G2 DNA damage checkpoint, 0006310=DNA recombination" "0000785=chromatin, 0005634=nucleus, 0005737=cytoplasm" "DmRECQ4, cg7487, CG7487, RECQL4, dRecQ4, RecQ4" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR021110=DNA replication/checkpoint protein, IPR004589=DNA helicase, ATP-dependent, RecQ type, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR001878=Zinc finger, CCHC-type" CG7487 16-Dec-15 2015_12 ENSXETG00000016582(RECQL4) ENSMUSG00000033762(Recql4) ENSG00000160957 "female sterile,partially lethal - majority live,cell cycle defective,radiation sensitive,developmental rate defective,recessive,germline clone,decreased cell size,endomitotic cell cycle defective,mitotic cell cycle defective,DNA repair defective,chemical sensitive,decreased cell number,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,viable,lethal,lethal - all die before end of larval stage,some die during larval stage" "egg,spiracle,oocyte,germline clone,cell & larval brain,cell & larval salivary gland,chromosome,cell & dorsal mesothoracic disc,eye,somatic clone,ommatidium,chorion,salivary gland,fat body,salivary gland imaginal ring,embryonic/larval brain" DRSC11265 K -0.481176399 0.152407668 -0.69920523 -0.452088587 3.123122742 1.432279476 FBgn0011785 BRWD3 BRWD3 http://flybase.net/reports/FBgn0011785.html "FBgn0011039, FBgn0039181, FBgn0040598, FBgn0051132, FBgn0061821, FBgn0061922" protein_coding_gene "0035562=negative regulation of chromatin binding, 0046427=positive regulation of JAK-STAT cascade, 0035096=larval midgut cell programmed cell death, 0046532=regulation of photoreceptor cell differentiation, 0006909=phagocytosis, 0010468=regulation of gene expression, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007095=mitotic G2 DNA damage checkpoint" "l(3)s5349, dBRWD3, psg13, CG18670, anon-WO0118547.520, l(3)05842, anon-WO0118547.620, ramshackle, CG6400, CG31132, ram, Brwd3, lethal (3) 05842, brwd3" "IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001487=Bromodomain, IPR018359=Bromodomain, conserved site, IPR001680=WD40 repeat" CG31132 16-Dec-15 2015_12 ENSDARG00000015970 "ENSXETG00000011747(PHIP),ENSXETG00000023728(BRWD1)" "ENSMUSG00000063663(Brwd3),ENSMUSG00000032253(Phip),ENSMUSG00000022914(Brwd1)" "ENSG00000165288(BRWD3),ENSG00000146247(PHIP),ENSG00000185658(BRWD1)" "lethal,recessive,partially lethal - majority die,visible,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval salivary gland,embryonic/larval midgut,eye,somatic clone,eye disc & nucleus | somatic clone,eye disc & actin cytoskeleton | somatic clone,rhabdomere & eye disc & pupa,wing vein,ectopic" DRSC15369 IEK -2.152006821 -1.467909399 -4.566517352 0.332917226 1.55042762 1.978675559 FBgn0021880 l(2)k13604 lethal (2) k13604 http://flybase.net/reports/FBgn0021880.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0034433 EndoB Endophilin B http://flybase.net/reports/FBgn0034433.html protein_coding_gene "0042171=lysophosphatidic acid acyltransferase activity, 0005543=phospholipid binding" "0030100=regulation of endocytosis, 0097320=membrane tubulation, 0007296=vitellogenesis, 0061024=membrane organization" "0005737=cytoplasm, 0016020=membrane" "D-EndoB, Endophilin, CG9834, endophilin B, EndoB, endoB, D-endoB, endophilin" "IPR001452=SH3 domain, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR004148=BAR domain" CG9834 16-Dec-15 2015_12 "ENSDARG00000035470(sh3glb2),ENSDARG00000045294(zgc:110259),ENSDARG00000071489,ENSDARG00000010956(sh3glb1),ENSDARG00000008983(zgc:158183)" WBGene00001335(erp-1) "ENSXETG00000012895(sh3glb2),ENSXETG00000000487(sh3glb1)" "ENSMUSG00000037062(Sh3glb1),ENSMUSG00000026860(Sh3glb2)" "ENSG00000148341(SH3GLB2),ENSG00000097033(SH3GLB1)" "lethal,recessive,female semi-sterile,partially lethal - majority die,visible" "yolk granule,oocyte,egg chamber,mesothoracic tergum,eye" FBgn0264404 FCG-G http://flybase.net/reports/FBgn0264404.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0060938 l(3)S040506 lethal (3) S040506 http://flybase.net/reports/FBgn0060938.html gene 0405/06 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0034998 CG13577 http://flybase.net/reports/FBgn0034998.html protein_coding_gene 0022008=neurogenesis CG13577 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0067357 l(3)8E276 lethal (3) 8E276 http://flybase.net/reports/FBgn0067357.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0083187 M(smoDN)K Modifier of smoDN group K http://flybase.net/reports/FBgn0083187.html gene 0007224=smoothened signaling pathway Group K 16-Dec-15 2015_12 "lethal,recessive,cell lethalcell lethal,somatic clone" FBgn0022084 l(2)k07502b lethal (2) k07502b http://flybase.net/reports/FBgn0022084.html gene "75/2, l(2)k07502B, l(2)k07502" 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0013576 mtd mustard http://flybase.net/reports/FBgn0013576.html "FBgn0027705, FBgn0037311, FBgn0040681, FBgn0052464" protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 2000648=positive regulation of stem cell proliferation, 0002218=activation of innate immune response, 0050829=defense response to Gram-negative bacterium" "0005634=nucleus, 0005737=cytoplasm" "late puff gene at 82F, CG10199, anon-EST:Posey263, CG10196, L82, CG32464, l(3)82FD, L(3)82Fd, l(3)82Fd" "IPR018392=LysM domain, IPR006571=TLDc domain" CG32464 16-Dec-15 2015_12 ENSDARG00000063310(si:dkeyp-84f11.5) WBGene00018700(F52E1.13) ENSXETG00000011699(NCOA7) "ENSMUSG00000039697(Ncoa7),ENSMUSG00000022307(Oxr1)" "ENSG00000111912(NCOA7),ENSG00000164830(OXR1)" "viable,fertile,oxidative stress response defective,stress response defective,lethal,recessive,eye color defective,some die during immature adult stage,visible,wild-type" "intestinal stem cell,pigment cell,trichogen cell,mesothoracic tergum" FBgn0024230 Hs2st Heparan sulfate 2-O-sulfotransferase http://flybase.net/reports/FBgn0024230.html FBgn0032784 protein_coding_gene 0004394=heparan sulfate 2-O-sulfotransferase activity "0007424=open tracheal system development, 0007165=signal transduction" 0016021=integral component of membrane "heparan-sulfate-2-sulfotransferase, dHS2ST, CG10234, 2-O sulfotransferase, Hs2st-2, dmHs2st, heparan sulfate 2-O-sulfotransferase, DmHs2st, HS2ST, HS 2-O, Hs2st, dmHS-2OST" "IPR007734=Heparan sulphate 2-O-sulfotransferase, IPR005331=Sulfotransferase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10234 16-Dec-15 2015_12 ENSDARG00000062078(hs2st1a) WBGene00002029(hst-2) ENSXETG00000013450(HS2ST1) ENSMUSG00000040151(Hs2st1) ENSG00000153936(HS2ST1) "increased mortality during development,viable,partially lethal - majority die" "interfollicle cell,ovariole,imaginal tracheoblast,dorsal branch,presumptive embryonic/larval tracheal system" DRSC03348 K -1.054025722 0.12617455 0.283607147 -0.221522725 1.6198076 0.141712734 FBgn0020653 Trxr-1 Thioredoxin reductase-1 http://flybase.net/reports/FBgn0020653.html "FBgn0027292, FBgn0028303, FBgn0029045, FBgn0040148, FBgn0066832, FBgn0066833" protein_coding_gene "0004791=thioredoxin-disulfide reductase activity, 0016209=antioxidant activity, 0050660=flavin adenine dinucleotide binding, 0042803=protein homodimerization activity, 0004362=glutathione-disulfide reductase activity" "0008340=determination of adult lifespan, 0006974=cellular response to DNA damage stimulus, 0055114=oxidation-reduction process, 0022008=neurogenesis, 0045454=cell redox homeostasis, 0001666=response to hypoxia" "0005875=microtubule associated complex, 0005739=mitochondrion, 0005737=cytoplasm, 0005829=cytosol" "DmTrxR, Thioredoxin reductase, dmtrxr-1, dTrxR, l(1)G0477, l(1)G0379, disulfide reductase, thioredoxin reductase, CG2151, anon-WO03040301.187, DmTrxR-1, TRR, Gr, GR, trxr-1, thioredoxin reductase-1, DmTR, TrxR-1, DTR, l(1)G0481, anon-WO03040301.185, 2151, TrxR, Trx, Glutathione reductase, DmTrx, TH, l(1)G0154, Trxr1, gr, Dm-TrxR, glutathione reductase" "IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR006338=Thioredoxin/glutathione reductase selenoprotein, IPR012999=Pyridine nucleotide-disulphide oxidoreductase, class I, active site, IPR016156=FAD/NAD-linked reductase, dimerisation domain, IPR004099=Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain" CG2151 16-Dec-15 2015_12 ENSDARG00000017864 YPL091W(GLR1) WBGene00015553(trxr-1) ENSXETG00000006307(TXNRD2) ENSMUSG00000075704(Txnrd2) ENSG00000184470(TXNRD2) embryonic stage -- adult stage "viable,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,wild-type,partially lethal - majority die,partially,developmental rate defective,male sterile,female,aging defective,lethal - all die before end of larval stage,some die during larval stage,stress response defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "adult abdomen,ganglion mother cell" FBgn0014859 Hr38 Hormone receptor-like in 38 http://flybase.net/reports/FBgn0014859.html FBgn0010510 protein_coding_gene "0003707=steroid hormone receptor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding" "0006909=phagocytosis, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0043401=steroid hormone mediated signaling pathway, 0042335=cuticle development, 0006355=regulation of transcription, DNA-templated, 0008544=epidermis development" 0005634=nucleus "Dhr38, 38E.3, CG1864, NR4A4, dHR38, DHR38, l(2)02306, hormone receptor-like in 38, HR38, 38E.7, hormone receptor 38, hr38" "IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR001628=Zinc finger, nuclear hormone receptor-type" CG1864 16-Dec-15 2015_12 "ENSDARG00000017007,ENSDARG00000044532(nr4a2b),ENSDARG00000055854(nr4a3)" "ENSMUSG00000028341(Nr4a3),ENSMUSG00000026826(Nr4a2)" "ENSG00000153234(NR4A2),ENSG00000119508(NR4A3),ENSG00000123358(NR4A1)" " embryonic stage , embryonic stage--pupal stage , larval stage&&prepupal stage " "lethal,recessive,visible,some die during immature adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,heat sensitive,viable" "embryonic/larval hemocyte | third instar larval stage,adult cuticle,joint,adult epidermis,leg,pupal epidermis,pupal cuticle" FBgn0015905 ast asteroid http://flybase.net/reports/FBgn0015905.html protein_coding_gene "0001752=compound eye photoreceptor fate commitment, 0007526=larval somatic muscle development, 0001745=compound eye morphogenesis, 0008586=imaginal disc-derived wing vein morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0007173=epidermal growth factor receptor signaling pathway" "S[r], Star-recessive, Star/asteroid, CG4426" "IPR026832=Asteroid, IPR029060=PIN domain-like" CG4426 16-Dec-15 2015_12 "ENSDARG00000062530,ENSDARG00000070132(aste1)" ENSXETG00000002328(ASTE1) ENSMUSG00000032567(Aste1) ENSG00000034533(ASTE1) " embryonic stage , larval stage | third instar , embryonic stage -- adult stage " morphogenetic furrow | anterior to

"visible,dominant,recessive,viable,wild-type,female sterile,lethal,partially" "wing vein,ectopic,wing,ommatidium,wing vein L2,wing vein L3,wing vein L4,wing vein L5,eye,embryonic somatic muscle,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 4" FBgn0000482 dor deep orange http://flybase.net/reports/FBgn0000482.html protein_coding_gene "0019905=syntaxin binding, 0005515=protein binding, 0008270=zinc ion binding" "0045746=negative regulation of Notch signaling pathway, 0035542=regulation of SNARE complex assembly, 0008333=endosome to lysosome transport, 0051301=cell division, 0007032=endosome organization, 0000046=autophagic vacuole fusion, 0009267=cellular response to starvation, 0008340=determination of adult lifespan, 0008057=eye pigment granule organization, 0016197=endosomal transport, 0007041=lysosomal transport, 0006728=pteridine biosynthetic process, 0007220=Notch receptor processing, 0006727=ommochrome biosynthetic process, 0007298=border follicle cell migration, 0006726=eye pigment biosynthetic process, 0006622=protein targeting to lysosome, 0048072=compound eye pigmentation, 0006897=endocytosis" "0030897=HOPS complex, 0033263=CORVET complex, 0045202=synapse, 0005768=endosome, 0005764=lysosome" "unnamed, l(1)2Bw, CG3093, dor1, l(1)2Be, l(1)7, Dor, l(1)76, EG:171E4.1, Deep orange, Dof, Deep Orange, Vps18, Deep-orange" "IPR000547=Clathrin, heavy chain/VPS, 7-fold repeat, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR007810=Pep3/Vps18/deep orange" CG3093 16-Dec-15 2015_12 ENSDARG00000070433(vps18) YLR148W(PEP3) WBGene00021058(vps-18) ENSXETG00000021575(VPS18) ENSMUSG00000034216(Vps18) ENSG00000104142(VPS18) embryonic stage -- adult stage " larval stage , pupal stage , adult stage | female , embryonic stage , adult stage | male " ovary

"lethal,viable,visible,heat sensitive,cold sensitive,short lived,female,male,eye color defective,recessive,lethal - all die before end of larval stage,some die during larval stage,male sterile,melanotic mass phenotype,male fertile,female fertile,reduced,cell death defective,decreased cell death,lethal - all die before end of pupal stage,some die during pupal stage,sterile,somatic clone,male limited,some die during third instar larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage" "eye,heat sensitive,thorax & macrochaeta | conditional cs,wing,late endosome,pigment cell,synapse,bouton,egg chamber,nurse cell,spermatogonial cyst,male germline cell,ovariole,germline clone,egg,Malpighian tubule,adult foregut,adult midgut,adult hindgut,somatic clone,eye photoreceptor cell,endosome | somatic clone,border follicle cell,polar follicle cell,embryonic/larval fat body,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0040985 CG6115 http://flybase.net/reports/FBgn0040985.html FBgn0063241 protein_coding_gene BcDNA:GH16758 IPR008011=Complex 1 LYR protein CG6115 16-Dec-15 2015_12 ENSDARG00000045827(zgc:162127) WBGene00012780(Y42A5A.5) ENSXETG00000004720(LYRM5) ENSMUSG00000040370(Lyrm5) ENSG00000205707(LYRM5) "viable,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02931 E -0.357015753 -1.028328435 -2.012748375 0.190264759 -0.643274271 -0.630016028 FBgn0060380 l(3)S135107 lethal (3) S135107 http://flybase.net/reports/FBgn0060380.html gene 1351/07 16-Dec-15 2015_12 "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0060960 l(3)S032414 lethal (3) S032414 http://flybase.net/reports/FBgn0060960.html gene 0324/14 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0029873 CG3918 http://flybase.net/reports/FBgn0029873.html protein_coding_gene "0003676=nucleic acid binding, 0008270=zinc ion binding" "IPR001878=Zinc finger, CCHC-type" CG3918 16-Dec-15 2015_12 ENSDARG00000043728(zgc:123019) WBGene00015746(C13F10.7) ENSXETG00000000461(TNeu060i09.1) ENSMUSG00000021716(Srsf12ip1) ENSG00000153006(SREK1IP1) "viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" DRSC28834 K -1.549512016 0.259407506 FBgn0036741 CG7510 http://flybase.net/reports/FBgn0036741.html FBgn0023103 protein_coding_gene "0055085=transmembrane transport, 0035556=intracellular signal transduction" 0016021=integral component of membrane "unnamed, anon-74EFa" "IPR004776=Auxin efflux carrier, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000591=DEP domain" CG7510 16-Dec-15 2015_12 "ENSDARG00000071086(LOC100005567),ENSDARG00000070332" ENSXETG00000008486(GPR155) ENSMUSG00000041762(Gpr155) ENSG00000163328(GPR155) "partially lethal - majority die,visible" mesothoracic tergum FBgn0034109 CG7747 http://flybase.net/reports/FBgn0034109.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0000413=protein peptidyl-prolyl isomerization, 0000398=mRNA splicing, via spliceosome, 0000209=protein polyubiquitination, 0006457=protein folding" "0005634=nucleus, 0071013=catalytic step 2 spliceosome" "NM 137269.2, CYC4" "IPR029000=Cyclophilin-like domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR027799=Replication termination factor 2, RING-finger" CG7747 16-Dec-15 2015_12 ENSDARG00000002016(ppil2) WBGene00000880(cyn-4) ENSXETG00000018594(TGas104a07.1) ENSMUSG00000022771(Ppil2) ENSG00000100023(PPIL2) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031298 Atg4a Autophagy-related 4a http://flybase.net/reports/FBgn0031298.html protein_coding_gene 0004197=cysteine-type endopeptidase activity "0010506=regulation of autophagy, 0010508=positive regulation of autophagy, 0035096=larval midgut cell programmed cell death" 0005829=cytosol "Atg4a, Atg4, atg4, AUT2, APG4, ATG4, Autophagy-specific gene 4, CG4428, Autophagy-specific gene 4a" IPR005078=Peptidase C54 CG4428 16-Dec-15 2015_12 "ENSDARG00000014531(atg4a),ENSDARG00000052104(atg4b)" YNL223W(ATG4) WBGene00013595(atg-4.1) "ENSXETG00000002981(ATG4B),ENSXETG00000012854(apg4a)" "ENSMUSG00000026280(Atg4b),ENSMUSG00000079418(Atg4a)" "ENSG00000168397(ATG4B),ENSG00000215697,ENSG00000101844(ATG4A)" "starvation stress response defective,somatic clone,viable" "embryonic/larval fat body,somatic clone | third instar larval stage,lysosome | somatic clone | third instar larval stage,autophagic vacuole | somatic clone | third instar larval stage" FBgn0003996 w white http://flybase.net/reports/FBgn0003996.html "FBgn0000561, FBgn0026792, FBgn0026850" protein_coding_gene "0005524=ATP binding, 0004888=transmembrane signaling receptor activity, 0005395=eye pigment precursor transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0008049=male courtship behavior, 0006726=eye pigment biosynthetic process, 0070731=cGMP transport, 0042332=gravitaxis, 0048072=compound eye pigmentation, 0006727=ommochrome biosynthetic process, 0006856=eye pigment precursor transport, 0042441=eye pigment metabolic process, 0042401=cellular biogenic amine biosynthetic process, 0007613=memory" "0005887=integral component of plasma membrane, 0043190=ATP-binding cassette (ABC) transporter complex, 0031410=cytoplasmic vesicle" "c23, enhancer of garnet, modifier of garnet, W, CG2759, mini-white, e(g), white[+], White, unnamed, EG:BACN33B1.1, w(AT)[[13]], mw, m(g), Hid, DMWHITE, BACN33B1.1" "IPR005284=Pigment precursor permease, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013525=ABC-2 type transporter, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG2759 16-Dec-15 2015_12 YCR011C(ADP1) WBGene00015479(wht-1) ENSXETG00000000340(abcg2) " larval stage , adult stage | female , adult stage | male , adult stage " head

"visible,recessive,eye color defective,conditional,courtship behavior defective,male,dominant,female,suppressor of variegation,viable,fertile,cold sensitive,heat sensitive,gravitaxis defective,chemical conditional,male fertile,male limited,wild-type,behavior defective,semidominant,chemical resistant,locomotor behavior defective,memory defective,long lived,modifier of variegation,body color defective" "pigment cell,embryonic/larval Malpighian tubule,testis pigment cell,Malpighian tubule,eye,conditional,male,female,ventral,ocellus,testis,cold sensitive,main segment of Malpighian tubule,ocellus pigment granule,retina,ommatidium,adult cuticle" FBgn0031973 Spn28Dc Serpin 28Dc http://flybase.net/reports/FBgn0031973.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0010951=negative regulation of endopeptidase activity, 0035009=negative regulation of melanization defense response, 0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis, 0009611=response to wounding" 0005615=extracellular space "Serpin-28D, Dm-serpin-28D, Spn28D, Dm-Spn28D, Serpin 28D, spn28D, CG7219, Spn28Dc" "IPR000215=Serpin family, IPR023796=Serpin domain" CG7219 16-Dec-15 2015_12 "viable,body color defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,recessive,wound healing defective,melanotic mass phenotype" "ptilinum,ptilinal suture,adult cuticle,melanotic mass,adult spiracle,haltere foramen,adult external abdomen,trachea,spiracle,pupa" FBgn0003312 sad shadow http://flybase.net/reports/FBgn0003312.html FBgn0037957 protein_coding_gene "0042768=ecdysteroid 2-hydroxylase activity, 0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" "0008258=head involution, 0007494=midgut development, 0007391=dorsal closure, 0007417=central nervous system development, 0008045=motor neuron axon guidance, 0055114=oxidation-reduction process, 0006697=ecdysone biosynthetic process" "0005739=mitochondrion, 0016020=membrane" "karmoisin ghost, CG14728, CYP315A1, Sad, 315a1, Cyp315a1, ecdysteroid hydroxylase, cytochrome P450" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG14728 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,recessive,viable" "presumptive embryonic/larval central nervous system,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,embryo,posterior,mitochondrion,axonExel7310),midgut constriction,embryonic/larval tracheal system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,embryonic/larval neuron,ectopic,longitudinal connective,glial cell,midline glial cell" FBgn0000394 cv crossveinless http://flybase.net/reports/FBgn0000394.html FBgn0029790 protein_coding_gene "0007630=jump response, 0048636=positive regulation of muscle organ development" "CG12410, crossvein, cv-1, tsg2, Crossveinless, Tsg2, twisted gastrulation 2, Cv" IPR006761=Twisted gastrulation (Tsg) protein CG12410 16-Dec-15 2015_12 ENSDARG00000033428 "ENSXETG00000004048(twsg1),ENSXETG00000014602(Q5FVZ5_XENTR)" ENSMUSG00000024098(Twsg1) ENSG00000128791(TWSG1) "viable,fertile,visible,recessive,jumping defective,partially,partially lethal - majority die,body color defective" "eye,anterior crossvein,posterior crossvein,crossvein,wing vein,wing vein L3,wing vein L4,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,mesothoracic tergum" FBgn0011722 Tig Tiggrin http://flybase.net/reports/FBgn0011722.html protein_coding_gene 0005178=integrin binding "0033628=regulation of cell adhesion mediated by integrin, 0031589=cell-substrate adhesion, 0007411=axon guidance, 0033627=cell adhesion mediated by integrin, 0034446=substrate adhesion-dependent cell spreading, 0006909=phagocytosis" "0031012=extracellular matrix, 0005578=proteinaceous extracellular matrix, 0005604=basement membrane" "TIG, CT36389, tiggrin, CG11527, tig" "IPR016084=Haem oxygenase-like, multi-helical" CG11527 16-Dec-15 2015_12 " embryonic stage | stage 14 , embryonic stage | stage 12 " " fat body

, hemocyte

" " embryonic stage , embryonic stage&&larval stage , adult stage " " metameric furrow

, hemocyte

, commissure

, muscle attachment site

, mesothoracic extracoxal depressor muscle 66

, embryonic/larval fat body

" "partially lethal - majority die,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "abdominal 7 segment border muscle,embryonic/larval somatic muscle,adult abdomen,wing,pupa,air bubble,fascicle,abdominal 2 ventral longitudinal muscle 3,abdominal 3 ventral longitudinal muscle 3,abdominal 4 ventral longitudinal muscle 3,abdominal 5 ventral longitudinal muscle 3,abdominal 6 ventral longitudinal muscle 3,abdominal 7 ventral longitudinal muscle 3,abdominal 2 ventral longitudinal muscle 4,abdominal 3 ventral longitudinal muscle 4,abdominal 4 ventral longitudinal muscle 4,abdominal 5 ventral longitudinal muscle 4,abdominal 6 ventral longitudinal muscle 4,abdominal 7 ventral longitudinal muscle 4,abdominal 2 lateral oblique muscle 1,abdominal 3 lateral oblique muscle 1,abdominal 4 lateral oblique muscle 1,abdominal 5 lateral oblique muscle 1,abdominal 6 lateral oblique muscle 1,abdominal 7 lateral oblique muscle 1,abdominal 2 segment border muscle,abdominal 3 segment border muscle,abdominal 4 segment border muscle,abdominal 5 segment border muscle,abdominal 6 segment border muscle" FBgn0002931 net net http://flybase.net/reports/FBgn0002931.html FBgn0031215 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity" "0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0008586=imaginal disc-derived wing vein morphogenesis, 0007474=imaginal disc-derived wing vein specification" 0005634=nucleus "Shout, shout, Group IId, bHLHc42, CG11450" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG11450 16-Dec-15 2015_12 WBGene00001954(hlh-10) "ENSXETG00000015485(Q6DEU8_XENTR),ENSXETG00000025372(Q6P1T1_XENTR),ENSXETG00000010956(Q5XGD6_XENTR)" "visible,dominant,recessive,semidominant,wild-type,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing vein,ectopic,1st posterior cell,marginal cell,submarginal cell,2nd posterior cell,3rd posterior cell,distal,posterior cell,wing vein L3,wing vein L4,wing vein L5" FBgn0000928 fs(1)Yb female sterile (1) Yb http://flybase.net/reports/FBgn0000928.html "FBgn0000897, FBgn0024974" protein_coding_gene "0007281=germ cell development, 0048477=oogenesis, 0048103=somatic stem cell division, 0030713=ovarian follicle cell stalk formation, 0042078=germ-line stem cell division, 0030718=germ-line stem cell maintenance" "0070725=Yb body, 0005737=cytoplasm" "female sterile(1)M104, EG:95B7.8, YB, Yb, no ovaries, CG2706, female sterile(1)Yb, fs(1)Y[b], fs(1)M104, nov" IPR027417=P-loop containing nucleoside triphosphate hydrolase CG2706 16-Dec-15 2015_12 " adult stage && oogenesis stage , larval stage && pupal stage && adult stage " " terminal filament

, ovariole

, epithelial sheath

" "female sterile,recessive,viable,male fertile,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,female fertile" "egg chamber,germarium,germline stem cell,follicle cell,egg,dorsal appendage,basal stalk,ovary,germline cyst,spectrosome,ovariole,maternal effect,nurse cell spectrosome,female germline stem cell,supernumerary,interfollicle cell" FBgn0028426 JhI-1 Juvenile hormone-inducible protein 1 http://flybase.net/reports/FBgn0028426.html FBgn0033506 protein_coding_gene "0016891=endoribonuclease activity, producing 5'-phosphomonoesters" "0022008=neurogenesis, 0045727=positive regulation of translation, 0046331=lateral inhibition, 0006388=tRNA splicing, via endonucleolytic cleavage and ligation, 0048477=oogenesis, 0036093=germ cell proliferation, 0042779=tRNA 3'-trailer cleavage, 0042780=tRNA 3'-end processing, 0030307=positive regulation of cell growth, 0001558=regulation of cell growth, 0006409=tRNA export from nucleus" "0005739=mitochondrion, 0005634=nucleus" "RNZ, dRNaseZ, tRNase Z, JHI-1, CG3298, unnamed, dRNase Z, dtRNaseZ, tRNAse Z" "IPR027794=tRNase Z endonuclease, IPR001279=Metallo-beta-lactamase" CG3298 16-Dec-15 2015_12 ENSDARG00000034060 YKR079C(TRZ1) WBGene00001983(hoe-1) ENSXETG00000012596(TEgg121f24.1) ENSMUSG00000020549(Elac2) ENSG00000006744(ELAC2) "lethal,lethal - all die before end of second instar larval stage,decreased cell size,cell autonomous,somatic clone,size defective,sterile,temperature conditional,lethal - all die before end of larval stage,mitotic cell cycle defective,neuroanatomy defective,partially lethal - majority die,some die during pharate adult stage,viable,visible,female limited,decreased cell growth,some die during third instar larval stage,recessive" "fat body,cell autonomous,somatic clone,eye disc,egg chamber,temperature conditional,oocyte,supernumerary,nurse cell,follicle cell,female germline cyst,testis,spermatogonium,spermatid,male germline cyst,Nebenkern,wing disc,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum,dorsal wing blade,female limited,wing blade,scutellum,eye,ommatidium,eye-antennal disc,head capsule" FBgn0061478 suo solofuso http://flybase.net/reports/FBgn0061478.html gene 0007060=male meiosis chromosome segregation 16-Dec-15 2015_12 "lethal,viable,sterile" "chromosome,metaphase & condensed nuclear chromosome,spindle,mitotic metaphase,metaphase & condensed nuclear chromosome & spermatocyte" FBgn0037351 RpL13A Ribosomal protein L13A http://flybase.net/reports/FBgn0037351.html "FBgn0025276, FBgn0026282" protein_coding_gene 0003735=structural constituent of ribosome "0007219=Notch signaling pathway, 0006412=translation, 0051298=centrosome duplication, 0008407=chaeta morphogenesis" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "putative ribosomal L13 protein, anon-EST:Posey125, anon-fast-evolving-1A5, 60S ribosomal protein L13A, M(3)83B, L13a2, Rp L13A, chr3R:1451210..1451407, Ribosomal protein L13a, cg1475, CG1475, ribosomal protein L13a, L13A, bs25f04.y1, unnamed, anon-EST:fe1A5" "IPR005822=Ribosomal protein L13, IPR023563=Ribosomal protein L13, conserved site, IPR005755=Ribosomal protein L13, eukaryotic/archaeal, IPR023564=Ribosomal protein L13 domain" CG1475 16-Dec-15 2015_12 ENSDARG00000044093(rpl13a) "YIL133C(RPL16A),YNL069C(RPL16B)" WBGene00004428(rpl-16) ENSXETG00000014144(rpl13a) "ENSMUSG00000003426,ENSMUSG00000062083(Rpl13a-ps1)" "ENSG00000142541(RPL13A),ENSG00000136149" "Minute,dominant,visible,lethal" macrochaeta DRSC12265 EK 0.103944708 -0.519731393 -1.126374924 -4.553400539 1.928877073 1.350087872 FBgn0010067 M(3)39b M(3)39b http://flybase.net/reports/FBgn0010067.html gene 16-Dec-15 2015_12 "female sterile,Minute,visible" macrochaeta FBgn0021872 Xbp1 X box binding protein-1 http://flybase.net/reports/FBgn0021872.html "FBgn0025990, FBgn0034593" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0042803=protein homodimerization activity" "0034976=response to endoplasmic reticulum stress, 0006990=positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response, 0030968=endoplasmic reticulum unfolded protein response, 0022416=chaeta development, 0006355=regulation of transcription, DNA-templated, 0035220=wing disc development, 0046331=lateral inhibition" 0005634=nucleus "X-box binding protein, X box binding protein 1, CG9415, Dxbp-1, xbp-1, dXbp-1, XBP-1, xbp1, XbpI, l(2)k13803, X-box-binding protein 1, XBP1, anon-EST:Liang-1.41, 138/3, Xbp-1, CG 9415, DM18, clone 1.41" IPR004827=Basic-leucine zipper domain CG9415 16-Dec-15 2015_12 ENSDARG00000035622(xbp1) WBGene00006959(xbp-1) ENSXETG00000027416(xbp1) ENSMUSG00000020484(Xbp1) ENSG00000100219(XBP1) "lethal,recessive,hypoactive,developmental rate defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,neuroanatomy defective,partially lethal - majority die,viable,visible,eye color defective" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,imaginal disc,wing,macrochaeta,supernumerary,scutum,scutellar bristle,chaeta,tormogen cell,eye,retina,photoreceptor cell,eye photoreceptor cell" FBgn0041733 mer-on-3 merlin on 3 http://flybase.net/reports/FBgn0041733.html gene "mer, merlin" 16-Dec-15 2015_12 "viable,chemical resistant,dominant,melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,tumorigenic" "salivary gland,melanotic mass,polytene chromosome,embryonic/larval brain" FBgn0035005 CG3483 http://flybase.net/reports/FBgn0035005.html FBgn0044772 protein_coding_gene "0051287=NAD binding, 0004449=isocitrate dehydrogenase (NAD+) activity, 0000287=magnesium ion binding" 0055114=oxidation-reduction process 0005759=mitochondrial matrix anon-WO0140519.111 "IPR024084=Isopropylmalate dehydrogenase-like domain, IPR001804=Isocitrate and isopropylmalate dehydrogenases family" CG3483 16-Dec-15 2015_12 viable FBgn0066333 pon::pins pon::raps http://flybase.net/reports/FBgn0066333.html engineered_fusion_gene pon::raps 16-Dec-15 2015_12 cell polarity defective neuroblast FBgn0065805 l(2)SH0396 lethal (2) SH0396 http://flybase.net/reports/FBgn0065805.html gene l(2)SH2 0396 16-Dec-15 2015_12 "lethal,recessive" FBgn0000562 egl egalitarian http://flybase.net/reports/FBgn0000562.html protein_coding_gene "0008408=3'-5' exonuclease activity, 0003729=mRNA binding" "0048477=oogenesis, 0006139=nucleobase-containing compound metabolic process, 0007436=larval salivary gland morphogenesis, 0007310=oocyte dorsal/ventral axis specification, 0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 0051028=mRNA transport, 0007294=germarium-derived oocyte fate determination, 0008298=intracellular mRNA localization, 0016325=oocyte microtubule cytoskeleton organization" "Egl, CG4051, egal, Egalitarian, EGL" "IPR002562=3'-5' exonuclease domain, IPR012337=Ribonuclease H-like domain" CG4051 16-Dec-15 2015_12 WBGene00015680(egal-1) adult stage && oogenesis stage oocyte

"O, adult stage && oogenesis stage " " germarium region 1 && germline cyst

, germarium region 3 && oocyte

posterior , germarium region 2b && presumptive oocyte | anterior , germarium region 2a && presumptive oocyte | anterior , germarium

" "female sterile,recessive,neuroanatomy defective,wild-type,viable" "ovary,germline cyst,vitellarium,nurse cell ring canal,anterior fascicle & synapse,embryonic/larval salivary gland,centrosome,oocyte,synaptonemal complex,synaptonemal complex | ectopic,nurse cell,ectopic,germarium region 2a,embryonic neuroblast,embryonic neuroblast & spindle,egg chamber,supernumerary,microtubule organizing centerbw-S46),microtubulebw-S46),embryonic epidermis,synapse,bouton,karyosome,lipid particlenos.UTR.THsimVP16,border follicle cell" FBgn0060993 l(3)S027335b lethal (3) S027335b http://flybase.net/reports/FBgn0060993.html gene 0273/35 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028692 Rpn2 Regulatory particle non-ATPase 2 http://flybase.net/reports/FBgn0028692.html protein_coding_gene "0008270=zinc ion binding, 0030234=enzyme regulator activity" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006974=cellular response to DNA damage stimulus, 0042176=regulation of protein catabolic process" "0005838=proteasome regulatory particle, 0000502=proteasome complex, 0008540=proteasome regulatory particle, base subcomplex" "CG11888, rpn2, S1, RPN2, 11888, PSMC1, p110, Rpn2, dRpn2" "IPR016024=Armadillo-type fold, IPR016642=26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit, IPR011989=Armadillo-like helical, IPR002015=Proteasome/cyclosome repeat" CG11888 16-Dec-15 2015_12 ENSDARG00000003189(psmd1) YIL075C(RPN2) WBGene00004459(rpn-2) ENSXETG00000009522(psmd1) ENSMUSG00000026229(Psmd1) ENSG00000173692(PSMD1) "lethal,decreased cell size,somatic clone" "fat body,somatic clone,autolysosomeCg.PA,autophagic vacuoleCg.PA" DRSC16839 IEK -2.709784312 -5.922021597 -3.147256482 -3.783050735 -1.013027346 -1.83673734 FBgn0028484 Ack Activated Cdc42 kinase http://flybase.net/reports/FBgn0028484.html FBgn0060299 protein_coding_gene "0042169=SH2 domain binding, 0005524=ATP binding, 0004715=non-membrane spanning protein tyrosine kinase activity, 0004713=protein tyrosine kinase activity" "0007391=dorsal closure, 0007286=spermatid development, 0034613=cellular protein localization, 0043066=negative regulation of apoptotic process, 0018108=peptidyl-tyrosine phosphorylation, 0007165=signal transduction, 0006468=protein phosphorylation" "0030136=clathrin-coated vesicle, 0005737=cytoplasm, 0071944=cell periphery" "DAck, Ack, ACK2, p145, ACK, DACK, CG14992, BcDNA:GH10777" "IPR000719=Protein kinase domain, IPR030220=Activated CDC42 kinase 1, IPR001452=SH3 domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR009060=UBA-like, IPR015940=Ubiquitin-associated domain, IPR017441=Protein kinase, ATP binding site, IPR020635=Tyrosine-protein kinase, catalytic domain" CG14992 16-Dec-15 2015_12 "ENSDARG00000062261,ENSDARG00000063281" ENSXETG00000003076(TNK2) ENSMUSG00000022791(Tnk2) ENSG00000061938(TNK2) "viable,visible,male sterile,female fertile,partially lethal - majority die,heat sensitive,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,some die during pupal stage" "sperm individualization complex,individualization stage spermatid,eye,elongation stage spermatid,spermatozoon,interommatidial bristle,supernumerary,pigment cell,embryo | dorsal closure stage,embryonic/first instar larval cuticle,heat sensitive,embryo,ommatidium,embryonic head,wing,wing vein,ectopic,mesothoracic tergum" FBgn0005194 l(2)S61 lethal of Seto 61 http://flybase.net/reports/FBgn0005194.html gene 16-Dec-15 2015_12 "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" "wing,leg,prepupa" FBgn0036153 CG7573 http://flybase.net/reports/FBgn0036153.html protein_coding_gene 0004222=metalloendopeptidase activity 0071586=CAAX-box protein processing 0016020=membrane "IPR001915=Peptidase M48, IPR027057=CAAX prenyl protease 1" CG7573 16-Dec-15 2015_12 "viable,fertile" FBgn0003406 sic sichel http://flybase.net/reports/FBgn0003406.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,cold sensitive,some die during embryonic stage,lethal" "denticle belt,maternal effect,cephalopharyngeal skeleton,embryo,cold sensitive,syncytial blastoderm embryo,ventral arm of pharyngeal sclerite" FBgn0033731 Cpr49Ah Cuticular protein 49Ah http://flybase.net/reports/FBgn0033731.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0022008=neurogenesis, 0040003=chitin-based cuticle development" 0031012=extracellular matrix "DmelCpr49Ah, CG8515" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG8515 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" DRSC07204 K -0.149871348 0.330760995 -0.604172435 -0.282381074 1.87566841 -0.019478545 FBgn0036248 ssp sunspot http://flybase.net/reports/FBgn0036248.html protein_coding_gene "0008013=beta-catenin binding, 0003677=DNA binding" "0032877=positive regulation of DNA endoreduplication, 0022008=neurogenesis, 0045572=positive regulation of imaginal disc growth, 0045893=positive regulation of transcription, DNA-templated" "0005635=nuclear envelope, 0016604=nuclear body" "Ssp, Sunspot, CG17153" "IPR026095=Myb/SANT-like DNA-binding domain-containing protein, IPR003656=Zinc finger, BED-type" CG17153 16-Dec-15 2015_12 "melanotic mass phenotype,decreased cell number,somatic clone,endomitotic cell cycle defective,lethal - all die before end of larval stage,some die during third instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "imaginal disc,embryonic/larval central nervous system,nucleus,embryonic/larval salivary gland,nucleusdpp.blk1,embryonic/larval neuroblast,mesothoracic tergum" DRSC10252 K -0.416058253 -0.94582291 -1.344245275 -0.40928378 1.502665533 -0.441335137 FBgn0003601 Su(var)3-10 Suppressor of variegation 3-10 http://flybase.net/reports/FBgn0003601.html gene Su-var(3)10 16-Dec-15 2015_12 "lethal,recessive,suppressor of variegation,dominant" FBgn0051989 Cap-D3 Chromosome associated protein D3 http://flybase.net/reports/FBgn0051989.html "FBgn0031712, FBgn0031714, FBgn0064854" protein_coding_gene "0003682=chromatin binding, 0035064=methylated histone binding" "1903775=regulation of DNA double-strand break processing, 0045950=negative regulation of mitotic recombination, 0051276=chromosome organization, 0007060=male meiosis chromosome segregation, 0051304=chromosome separation, 0007076=mitotic chromosome condensation" "0000796=condensin complex, 0000775=chromosome, centromeric region, 0000799=nuclear condensin complex, 0005634=nucleus" "CG6922, BcDNA:RE74832, CapD3, CG31989, CAP-D3, CG14019, CAP-D2, dCap-D3, cap-D3" "IPR016024=Armadillo-type fold, IPR026971=Condensin subunit 1/Condensin-2 complex subunit D3, IPR012371=Condensin-2 complex subunit D3, IPR011989=Armadillo-like helical" CG31989 16-Dec-15 2015_12 ENSXETG00000008336(NCAPD3) ENSMUSG00000035024(Ncapd3) ENSG00000151503(NCAPD3) "viable,male fertile,female fertile,male sterile,meiotic cell cycle defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,immune response defective" "primary spermatocyte in meiotic prophase I,primary spermatocyte in meiotic anaphase I,polytene chromosome & nurse cellExel7023),trichogen cell" FBgn0061515 endos endosulfine http://flybase.net/reports/FBgn0061515.html "FBgn0026212, FBgn0036401" protein_coding_gene "0017098=sulfonylurea receptor binding, 0004864=protein phosphatase inhibitor activity" "0051445=regulation of meiotic cell cycle, 0007088=regulation of mitotic nuclear division, 0007584=response to nutrient, 0034048=negative regulation of protein phosphatase type 2A activity, 0048477=oogenesis, 0030104=water homeostasis, 0007052=mitotic spindle organization, 0035308=negative regulation of protein dephosphorylation, 0007067=mitotic nuclear division" "End, l(3)S067006, 0670/06, alpha-endosulfine, CG6513, Endosulfine, dendos" IPR006760=Endosulphine CG6513 16-Dec-15 2015_12 "ENSDARG00000032532(arpp19a),ENSDARG00000039880(arpp19b),ENSDARG00000061644(si:dkey-30o16.6),ENSDARG00000036944(ensa)" WBGene00010730(K10C3.2) "ENSXETG00000026684(ensa),ENSXETG00000027097(arpp19)" "ENSMUSG00000038619(Ensa),ENSMUSG00000007656(Arpp19)" "ENSG00000128989(ARPP19),ENSG00000204637,ENSG00000143420(ENSA),ENSG00000177261" larval stage | third instar " Malpighian tubule

, larval brain

, embryonic/larval proventriculus

" "lethal,mitotic cell cycle defective,meiotic cell cycle defective,female sterile,recessive,visible,male sterile,lethal - all die before end of P-stage,some die during pharate adult stage,male fertile,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,stage S14 oocyte,follicle cell,egg,germline clone,oocyte,spindle & oocyte,spindle | embryonic stage | maternal effect,wing,tergite,leg,chaeta,embryonic/larval brain" DRSC10658 IK 1.710128713 1.215033052 0.865044774 0.521656318 0.316794094 1.962498917 FBgn0002441 l(3)mbt lethal (3) malignant brain tumor http://flybase.net/reports/FBgn0002441.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0043035=chromatin insulator sequence binding, 0005515=protein binding" "0007517=muscle organ development, 0035190=syncytial nuclear migration, 0007405=neuroblast proliferation, 0007347=regulation of preblastoderm mitotic cell cycle, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0010629=negative regulation of gene expression, 0048813=dendrite morphogenesis, 0008285=negative regulation of cell proliferation" "0031523=Myb complex, 0005634=nucleus, 0005737=cytoplasm, 0005700=polytene chromosome" "L(3)MBT, dl(3)MBT, CG5954, dL(3)mbt, L(3)mbt, L(3)MBT/LIN-61, tumor-supressor, mbt, MBT, L3mbt, l(3)malignant braintumor" "IPR003118=Pointed domain, IPR013761=Sterile alpha motif/pointed domain, IPR004092=Mbt repeat" CG5954 16-Dec-15 2015_12 " larval stage | third instar , larval stage | second instar , embryonic stage | >=0-3 hr , larval stage | first instar , embryonic stage | 0-3 hr , pupal stage , embryonic stage | stage 16 , embryonic stage | stage 16-17 , embryonic stage | 3-6 hr , adult stage | female , embryonic stage | stage 5 , embryonic stage | stage 1 , embryonic stage | stage 10 , larval stage&&pupal stage , larval stage && pupal stage , embryonic stage | stage 9 " " larval inner optic anlage

, larval brain

, subesophageal ganglion

, embryonic/larval foregut

, embryonic/larval hindgut

,

ubiquitous , imaginal disc

, ring gland

, embryonic/larval midgut

, procephalic neurogenic region

, lymph gland

, cephalic furrow

, muscle cell

, embryonic/larval fat body

, larval outer optic anlage

" "neuroanatomy defective,lethal,tumorigenic,recessive,wild-type,hyperplasia,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,maternal effect,female sterile,viable" "larval inner optic anlage,larval outer optic anlage,embryonic/larval brain,heat sensitive,neuroblast,ganglion mother cell,imaginal disc,wing disc,embryonic/larval optic lobe,ventral nerve cord,pole cell,germline clone,maternal effect,cleavage nucleus,ovary,germarium,egg" DRSC16983 EK 0.249292801 -0.021047596 1.368087409 -1.736603065 1.146873024 2.077337472 FBgn0040237 bor belphegor http://flybase.net/reports/FBgn0040237.html "FBgn0038409, FBgn0040482" protein_coding_gene 0005524=ATP binding "0005739=mitochondrion, 0005737=cytoplasm" "Belphegor, CP89BC, Cytoplasmic Protein 89BC, Bor, ATAD3A, CG6815, dATAD3A" "IPR003593=AAA+ ATPase domain, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR021911=ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523" CG6815 16-Dec-15 2015_12 ENSDARG00000071559 WBGene00010015(atad-3) ENSXETG00000012959(Atad3a) ENSMUSG00000029036(Atad3a) "ENSG00000197785(ATAD3A),ENSG00000160072(ATAD3B),ENSG00000219860" "female fertile,male sterile,meiotic cell cycle defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,female semi-sterile" "centrosome, with asund93,spermatocyte,spermatid,trichogen cell" FBgn0015509 Cul1 Cullin 1 http://flybase.net/reports/FBgn0015509.html "FBgn0020308, FBgn0022252" protein_coding_gene 0031625=ubiquitin protein ligase binding "0007095=mitotic G2 DNA damage checkpoint, 0016322=neuron remodeling, 0043066=negative regulation of apoptotic process, 0016567=protein ubiquitination, 0032007=negative regulation of TOR signaling, 0030163=protein catabolic process, 0046627=negative regulation of insulin receptor signaling pathway, 0006511=ubiquitin-dependent protein catabolic process" "0019005=SCF ubiquitin ligase complex, 0005634=nucleus, 0000152=nuclear ubiquitin ligase complex" "lin19-like, Lin19, Cul1[Ex], l(2)k01207, cullin1, dCUL1, CG1877, lin-19-like, Cul-1, lin-19/cul-1, Cullin-1, Q9V312, Cullin1, lin 19, Cullin 1, lin19, dCul-1, CUL1, l(2)02074, dCul1, cullin-1, Lin-19, dmCUL1, dCullin, cul-1, Cul1, cul1, Cullin, dCullin1" "IPR016157=Cullin, conserved site, IPR019559=Cullin protein, neddylation domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR016159=Cullin repeat-like-containing domain, IPR001373=Cullin, N-terminal, IPR016158=Cullin homology" CG1877 16-Dec-15 2015_12 "ENSDARG00000019239(cul1a),ENSDARG00000007691(cul1b)" YDL132W(CDC53) "WBGene00000836(cul-1),WBGene00000841(cul-6)" ENSXETG00000020148(CUL1) ENSMUSG00000029686(Cul1) ENSG00000055130(CUL1) "neuroanatomy defective,somatic clone,decreased cell death,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,visible,increased cell death,lethal,female sterile,germline clone" "dorsal multidendritic neuron ddaC,somatic clone,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaF,gamma Kenyon cell,alpha/beta Kenyon cell,dorsal multidendritic neuron ddaC | pupal stage,eye,wing,wing disc,eye disc,neuroblast,ovary,germline clone" DRSC07645 IK -0.297609348 1.528001415 -0.085725353 0.866010574 -0.692103751 2.337846572 FBgn0004244 Rdl Resistant to dieldrin http://flybase.net/reports/FBgn0004244.html FBgn0010390 protein_coding_gene "0016917=GABA receptor activity, 0005230=extracellular ligand-gated ion channel activity, 0004890=GABA-A receptor activity" "0002121=inter-male aggressive behavior, 0006811=ion transport, 0050805=negative regulation of synaptic transmission, 0046682=response to cyclodiene, 0042749=regulation of circadian sleep/wake cycle, 0009612=response to mechanical stimulus, 0030431=sleep, 0042493=response to drug, 0090328=regulation of olfactory learning" "0016021=integral component of membrane, 0030424=axon, 0005886=plasma membrane, 0030425=dendrite" "Resistance to dieldrin, Resistant to Dieldrin, LCCH1, GABA[[A]]R, gaba, Rd1, DmRDL, CG10537, GABA[[A]] receptor, DmRdl, unnamed, Resistance to Dieldrin, resistant to dieldrin, GABA receptor, GABA A beta-subunit, resistance to dieldrin, GABA, RDL, GABA[[A]], CT29555, rdl, GABAr" "IPR006201=Neurotransmitter-gated ion-channel, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR002289=Gamma-aminobutyric-acid A receptor, beta subunit, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain" CG10537 16-Dec-15 2015_12 "ENSDARG00000058103(glra4b),ENSDARG00000006865(glra4a),ENSDARG00000052769(glrbb),ENSDARG00000019169(LOC100333924),ENSDARG00000052782(glrba)" WBGene00017389(lgc-38) "ENSMUSG00000038257(Glra3),ENSMUSG00000018595(Glra4),ENSMUSG00000018589(Glra2),ENSMUSG00000000263(Glra1),ENSMUSG00000028020(Glrb)" adult stage adult head

"lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,chemical resistant,heat stress response defective,wild-type,chemical sensitive,dominant,some die during immature adult stage,semidominant,behavior defective,heat sensitive,male sterile,viable,learning defective,circadian behavior defective,neuroanatomy defective" "VUM neuron,aCC neuron,RP2 motor neuron,intersegmental nerve,abdominal intersegmental nerve,mesothoracic intersegmental nerve,metathoracic intersegmental nerve,prothoracic intersegmental nerve,U neuron" FBgn0001565 Hlc Helicase http://flybase.net/reports/FBgn0001565.html protein_coding_gene "0003676=nucleic acid binding, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" 0022008=neurogenesis "unnamed, HM-44, CG1666, HLC, lA112, l(1)19Ff, l(1)A112, section 14, l(1)S-19F6, 7, A112, l(1)11P1, DmRH10, hlc, l(1)8-1, 11P1, section 7, 14, l11P1, helicase, RNA helicase gene, lethal(1)19Ff" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR014014=RNA helicase, DEAD-box type, Q motif" CG1666 16-Dec-15 2015_12 ENSDARG00000020913(ddx56) YLR276C(DBP9) WBGene00016073(C24H12.4) ENSXETG00000019000(DDX56) ENSMUSG00000004393(Ddx56) ENSG00000136271(DDX56) " larval stage , adult stage && oogenesis stage , embryonic stage -- adult stage , adult stage , pupal stage | late " " embryonic/larval fat body

, ovary

, larval brain

, imaginal disc

, embryonic/larval salivary gland

, adult brain

, brain

" "viable,fertile,wild-type,lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "central nervous system,peripheral nervous system,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0029925 CG3040 http://flybase.net/reports/FBgn0029925.html protein_coding_gene CT9706 "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG3040 16-Dec-15 2015_12 ENSDARG00000043938(lrrc57) ENSXETG00000000060(LRRC57) ENSMUSG00000027286(Lrrc57) ENSG00000180979(LRRC57) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0034258 eIF3-S8 eIF3-S8 http://flybase.net/reports/FBgn0034258.html protein_coding_gene "0003743=translation initiation factor activity, 0031369=translation initiation factor binding" 0006413=translational initiation "0005852=eukaryotic translation initiation factor 3 complex, 0005739=mitochondrion, 0005829=cytosol" "eIF3c, eIF3-s8, CG4954" "IPR027516=Eukaryotic translation initiation factor 3 subunit C, IPR000717=Proteasome component (PCI) domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR008905=Eukaryotic translation initiation factor 3 subunit C, N-terminal domain" CG4954 16-Dec-15 2015_12 ENSDARG00000016443(eif3c) YMR309C(NIP1) WBGene00001226(eif-3.C) ENSXETG00000002941(eif3s8) ENSMUSG00000030738(Eif3c) "ENSG00000184110(EIF3C),ENSG00000205609(EIF3CL)" "lethal,recessive" DRSC06905 IE -2.087736444 -0.950672904 -3.280064155 -3.808465902 0.154091937 1.027664046 FBgn0020440 Fak Focal adhesion kinase http://flybase.net/reports/FBgn0020440.html protein_coding_gene "0005524=ATP binding, 0004713=protein tyrosine kinase activity, 0004871=signal transducer activity" "0007229=integrin-mediated signaling pathway, 0007016=cytoskeletal anchoring at plasma membrane, 0007172=signal complex assembly, 0043407=negative regulation of MAP kinase activity, 0006468=protein phosphorylation, 0008360=regulation of cell shape, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0042059=negative regulation of epidermal growth factor receptor signaling pathway" "0061177=type Is terminal bouton, 0005925=focal adhesion, 0005856=cytoskeleton, 0061176=type Ib terminal bouton" "Dfak56, CT28129, protein tyrosine kinase 2, Fak, dFak, fak56, DFak, Focal Adhesion Kinase, DmFAK, Dfak, Fak56, DFAK, DFak56, FAK, CG10023, fak, Focal adhesion kinase, focal adhesion kinase homolog, focal adhesion kinase, Fak56D, FAK65D, ptk2" "IPR019749=Band 4.1 domain, IPR019748=FERM central domain, IPR005189=Focal adhesion kinase, targeting (FAT) domain, IPR008266=Tyrosine-protein kinase, active site, IPR029071=Ubiquitin-related domain, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000299=FERM domain" CG10023 16-Dec-15 2015_12 "ENSDARG00000004672(ptk2.1),ENSDARG00000022841,ENSDARG00000039577(snx17)" "ENSXETG00000023764(ptk2),ENSXETG00000017538(Q5XH98_XENTR)" "ENSMUSG00000022607(Ptk2),ENSMUSG00000059456(Ptk2b)" "ENSG00000169398(PTK2),ENSG00000120899(PTK2B)" " embryonic stage -- adult stage , embryonic stage | stage 16 , embryonic stage | stage >=14 , embryonic stage && larval stage , embryonic stage , embryonic stage | stage 13 " " muscle attachment site

, embryonic brain

, organism

,

ubiquitous , embryonic central nervous system

, midgut primordium

" " adult stage && oogenesis stage | stage S9 , embryonic stage -- adult stage , embryonic stage , pupal stage | early , embryonic stage | stage >=13 , embryonic stage | stage 16 , adult stage && oogenesis stage | stage S1-6 , adult stage && oogenesis stage " " border follicle cell

, embryonic central nervous system

, ovarian sheath cell

, muscle attachment site

, egg chamber

,

ubiquitous , follicle cell

, embryonic/larval midgut

" "neuroanatomy defective,viable,fertile,neurophysiology defective,visible,female" "neuromuscular junction | third instar larval stageelav.PU,NMJ bouton,supernumerary | third instar larval stage,axon & eye photoreceptor cell,embryonic/larval optic stalk,subretinal glial cell,synapse,bouton,neuromuscular junction | third instar larval stage,wing,female,posterior,muscle attachment site | embryonic stage,medial longitudinal fascicle | embryonic stage,lateral longitudinal fascicle | embryonic stage,supernumerary" FBgn0016690 Opl Opthalmopedia-like http://flybase.net/reports/FBgn0016690.html gene 0035214=eye-antennal disc development 16-Dec-15 2015_12 "lethal,recessive" "retina,rhabdomere" FBgn0063777 vacu vacuous http://flybase.net/reports/FBgn0063777.html gene 0007417=central nervous system development ND12 16-Dec-15 2015_12 "paralytic,heat sensitive,short lived,neurophysiology defective,locomotor behavior defective,flight defective" "central nervous system,optic lobe,thoracico-abdominal ganglion,brain" FBgn0011836 Taf2 TBP-associated factor 2 http://flybase.net/reports/FBgn0011836.html protein_coding_gene "0008134=transcription factor binding, 0008270=zinc ion binding, 0008237=metallopeptidase activity, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, 0043565=sequence-specific DNA binding, 0001129=TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly" "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0046427=positive regulation of JAK-STAT cascade, 0007221=positive regulation of transcription of Notch receptor target, 0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0005634=nucleus, 0005669=transcription factor TFIID complex" "TAFII150, TAF[II]150, TFIID, TAF, dTAF[[II]]150, TAF150, TBP-associated factor, Taf[[II]]150, TAF[[II]]150, dTAF II 150, CG6711, TafII150, TBP-associated factor 150kD, TAF2, dTAF150, Taf150, dTAFII150, TAF[[II]]" "IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR016024=Armadillo-type fold" CG6711 16-Dec-15 2015_12 ENSDARG00000038423(taf2) YCR042C(TAF2) WBGene00006383(taf-2) ENSMUSG00000037343(Taf2) ENSG00000064313(TAF2) "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female sterile" "embryonic/larval neuroblast,ganglion mother cell" DRSC11298 IEK -1.896211508 1.472208839 -1.587347023 0.243070858 1.335717424 1.797060189 FBgn0263251 vnc variable nurse cells http://flybase.net/reports/FBgn0263251.html "FBgn0042626, FBgn0002213, FBgn0036064" protein_coding_gene "0004402=histone acetyltransferase activity, 0004596=peptide alpha-N-acetyltransferase activity" "0022008=neurogenesis, 0048477=oogenesis" "Dromel_CG11989_FBtr0076348_ard1_mORF, Arrest defective 1, l(3)67BDk, ARD1, variable nurse cell, dArd1, Arrest Defective1, arrest defective1, Ard1, NAA10, ard1, CG11989, lethal (3) 67BDk, DmAAF50178" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG11989 16-Dec-15 2015_12 "ENSDARG00000071057(naa10),ENSDARG00000071060(LOC100331779)" YHR013C(ARD1) WBGene00019505(K07H8.3) ENSXETG00000021724(ard1a) "ENSMUSG00000031388(Naa10),ENSMUSG00000024571(Txnl4a),ENSMUSG00000046000(Naa11)" "ENSG00000102030(NAA10),ENSG00000156269(NAA11)" DRSC09867 I 0.354908156 1.615056328 0.90515488 0.742195521 -0.302816717 1.291736301 FBgn0250746 Prosë_7 Proteasome ë_7 subunit http://flybase.net/reports/FBgn0250746.html "FBgn0243587, FBgn0062092, FBgn0037314" protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" "0051297=centrosome organization, 0008283=cell proliferation, 0051603=proteolysis involved in cellular protein catabolic process, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006974=cellular response to DNA damage stimulus, 0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0090307=mitotic spindle assembly, 0022008=neurogenesis" "0000502=proteasome complex, 0005839=proteasome core complex" "beta-4, CG12000, anon-WO0118547.326, beta7, Proteasome beta4 subunit, Beta-7, Prosbeta7, 12000, 154275_at, GC12000, Prot. beta4, beta-7, Prosbeta4, beta-type 4 subunit" "IPR001353=Proteasome, subunit alpha/beta, IPR016050=Proteasome beta-type subunit, conserved site, IPR016295=Proteasome endopeptidase complex, beta subunit, IPR023333=Proteasome B-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal" CG12000 16-Dec-15 2015_12 ENSDARG00000054696(psmb4) YFR050C(PRE4) WBGene00003953(pbs-7) ENSMUSG00000005779(Psmb4) ENSG00000159377(PSMB4) DRSC12186 IEK -1.783588051 -3.804350521 -1.529653384 -1.839486055 1.916898999 0.446617913 FBgn0035510 Cpr64Aa Cuticular protein 64Aa http://flybase.net/reports/FBgn0035510.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "DmelCpr64Aa, CG15006" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG15006 16-Dec-15 2015_12 viable DRSC08460 E -1.310413269 -0.426565918 -1.598642077 0.42905313 0.578638093 0.58421029 FBgn0037149 CG14561 http://flybase.net/reports/FBgn0037149.html protein_coding_gene CG14561 16-Dec-15 2015_12 DRSC11722 K 0.242298741 0.47774807 -0.773237905 0.277628679 1.509449882 -0.020575639 FBgn0050441 CG30441 http://flybase.net/reports/FBgn0050441.html FBan0030441 protein_coding_gene 0042384=cilium assembly "0030992=intraciliary transport particle B, 0005929=cilium" IFT20 IPR028172=Intraflagellar transport protein 20 CG30441 16-Dec-15 2015_12 ENSDARG00000040556(ift20) WBGene00022465(Y110A7A.20) ENSXETG00000019444(TGas049d15.1) ENSMUSG00000001105(Ift20) ENSG00000109083(IFT20) viable DRSC22660 E 1.102991943 0.397278837 0.142389746 1.898136379 -0.87807626 -1.153295885 FBgn0039773 CG2224 http://flybase.net/reports/FBgn0039773.html protein_coding_gene 0004843=ubiquitin-specific protease activity 0016579=protein deubiquitination "Amsh, Q9VA71" "IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR015063=USP8 dimerisation domain" CG2224 16-Dec-15 2015_12 "ENSDARG00000054501(LOC100329968),ENSDARG00000003085(LOC570542),ENSDARG00000003033" ENSXETG00000007783(STAMBP) "ENSMUSG00000006906(Stambp),ENSMUSG00000024776(Stambpl1)" "ENSG00000124356(STAMBP),ENSG00000138134(STAMBPL1)" "viable,locomotor behavior defective" DRSC24269 K 0.125453121 -0.520729184 -0.687133403 -0.295994943 -1.688873431 -0.897009077 FBgn0030141 Gga "Golgi-localized, ë_-adaptin ear containing, ARF binding protein" http://flybase.net/reports/FBgn0030141.html protein_coding_gene "0008565=protein transporter activity, 0005515=protein binding, 0032050=clathrin heavy chain binding" "0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0006892=post-Golgi vesicle-mediated transport" "0005737=cytoplasm, 0005829=cytosol, 0030131=clathrin adaptor complex, 0048471=perinuclear region of cytoplasm, 0030136=clathrin-coated vesicle, 0005802=trans-Golgi network" "Gga, Golgi-localized, gamma-adaptin ear containing, ARF binding protein, DmGGA1, CG3002, dGGA, Golgi-localised, gamma-ear containing, ADP ribosylation factor-binding, dmGGA, GGA" "IPR013041=Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR002014=VHS domain, IPR008152=Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR008153=Clathrin adaptor, gamma-adaptin, appendage, IPR008942=ENTH/VHS, IPR004152=GAT domain" CG3002 16-Dec-15 2015_12 "ENSDARG00000038537(gga1),ENSDARG00000058987(LOC100334661),ENSDARG00000013479(gga3)" "ENSXETG00000016005(gga1),ENSXETG00000012511(GGA3)" "ENSMUSG00000033128(Gga1),ENSMUSG00000020740(Gga3),ENSMUSG00000030872(Gga2)" "ENSG00000100083(GGA1),ENSG00000125447(GGA3),ENSG00000103365(GGA2)" "viable,fertile,chemical sensitive,starvation stress response defective,partially lethal - majority die,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,neuroanatomy defective,progressive,visible,size defective,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere R7,retina,photoreceptor cell,cell body rind of lamina,vacuoleGMR.PF,eye photoreceptor cell,rhabdomere of eye photoreceptor cell,pigment granuleGMR.PF, ey.PH,progressive,eye,interommatidial bristle" FBgn0070049 3L-200-14 3L-200-14 http://flybase.net/reports/FBgn0070049.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect" FBgn0036727 CG7589 http://flybase.net/reports/FBgn0036727.html protein_coding_gene 0016933=extracellular-glycine-gated ion channel activity "0006811=ion transport, 0006909=phagocytosis" 0016021=integral component of membrane "ligand-gated chloride channel, CT23187" "IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006201=Neurotransmitter-gated ion-channel, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG7589 16-Dec-15 2015_12 "viable,lethal" DRSC10887 K -0.222288924 -0.172182367 -0.021731693 0.189480702 1.662892238 -1.225848599 FBgn0030864 CG8173 http://flybase.net/reports/FBgn0030864.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" 0006468=protein phosphorylation "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG8173 16-Dec-15 2015_12 ENSDARG00000007221(pbk) ENSXETG00000020438(pbk) ENSMUSG00000022033(Pbk) ENSG00000168078(PBK) "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0016926 Pino Pinocchio http://flybase.net/reports/FBgn0016926.html "FBgn0031303, FBgn0062225" protein_coding_gene "0042048=olfactory behavior, 2001020=regulation of response to DNA damage stimulus" "pinocchio, smell impaired 21F, smell imparied 21 F, CG4710, smi21F, smell impaired 21 F, anon-WO0118547.131" CG4710 16-Dec-15 2015_12 "viable,neurophysiology defective,smell perception defective,behavior defective,recessive,male,female,fertile" antenna DRSC00662 E -0.019324024 -0.781028941 1.098479244 -2.74748845 -1.029107647 0.344127355 FBgn0060431 l(3)S125816b lethal (3) S125816b http://flybase.net/reports/FBgn0060431.html gene 16-Dec-15 2015_12 lethal FBgn0005133 l(1)Y12 lethal (1) Y12 http://flybase.net/reports/FBgn0005133.html gene 16-Dec-15 2015_12 "visible,lethal - all die before end of embryonic stage,some die during embryonic stage" wing FBgn0036298 nst nesthocker http://flybase.net/reports/FBgn0036298.html protein_coding_gene "0000287=magnesium ion binding, 0004610=phosphoacetylglucosamine mutase activity" "0060438=trachea development, 0006048=UDP-N-acetylglucosamine biosynthetic process, 0045743=positive regulation of fibroblast growth factor receptor signaling pathway, 0005975=carbohydrate metabolic process, 0001707=mesoderm formation" 0005829=cytosol CG10627 "IPR005843=Alpha-D-phosphohexomutase, C-terminal, IPR005844=Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR016066=Alpha-D-phosphohexomutase, conserved site, IPR016055=Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR016657=Phosphoacetylglucosamine mutase" CG10627 16-Dec-15 2015_12 ENSDARG00000024654(pgm3) YEL058W(PCM1) WBGene00009006(F21D5.1) ENSXETG00000022673(PGM3) ENSMUSG00000056131(Pgm3) ENSG00000013375(PGM3) "lethal,viable" "mesoderm,germline clone,embryonic/larval dorsal trunk" FBgn0004478 l(1)air2 lethal aberrant immune response 2 http://flybase.net/reports/FBgn0004478.html gene air2 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "embryonic/larval brain,embryonic/larval lymph gland,melanotic mass" FBgn0037917 wkd whacked http://flybase.net/reports/FBgn0037917.html protein_coding_gene 0005096=GTPase activator activity "0035149=lumen formation, open tracheal system, 0007430=terminal branching, open tracheal system, 0043087=regulation of GTPase activity, 0060439=trachea morphogenesis" 0030175=filopodium "cg5344, CG5344, Whacked, Wkd" IPR000195=Rab-GTPase-TBC domain CG5344 16-Dec-15 2015_12 ENSDARG00000060096(LOC562628) WBGene00019915(tbc-10) "ENSXETG00000016143(),ENSXETG00000018905(TBC1D10B)" "ENSMUSG00000034412(Tbc1d10a),ENSMUSG00000040247(Tbc1d10c)" "ENSG00000099992(TBC1D10A),ENSG00000169221(TBC1D10B),ENSG00000175463(TBC1D10C)" "lethal,viable,lethal - all die before end of P-stage,some die during pharate adult stage" "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,tracheal fusion cell" DRSC15777 K 0.629129246 0.312149591 0.370484696 0.653728399 1.575268059 -1.403527005 FBgn0028189 l(3)S023549 lethal (3) S023549 http://flybase.net/reports/FBgn0028189.html FBgn0060613 gene "l(3)S090101, 0235/49, 0901/01" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0061043 l(3)S023723 lethal (3) S023723 http://flybase.net/reports/FBgn0061043.html gene 0237/23 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0003462 Sod Superoxide dismutase http://flybase.net/reports/FBgn0003462.html protein_coding_gene "0005507=copper ion binding, 0042803=protein homodimerization activity, 0008270=zinc ion binding, 0016209=antioxidant activity, 0004784=superoxide dismutase activity" "0006979=response to oxidative stress, 0001306=age-dependent response to oxidative stress, 2000331=regulation of terminal button organization, 0055114=oxidation-reduction process, 0019430=removal of superoxide radicals, 0007568=aging, 0006801=superoxide metabolic process, 0008340=determination of adult lifespan, 1903146=regulation of mitochondrion degradation" "0005777=peroxisome, 0005634=nucleus, 0005829=cytosol, 0005737=cytoplasm, 0005739=mitochondrion" "Cu[2+]/Zn[2+]SOD, Sod-1, copper and zinc SOD, SOD1, sod1, Cu/Zn SOD, SOD-1, CuSOD, Cu,Zn SOD, heart morphogenesis ; GO:0003007 | IMP, Cu/Zn-Superoxide dismutase, Cu-Zn superoxide dismutase, cSOD, superoxido dismutase, dismutase, To, CuZnSOD, CuZn superoxide dismutase, superoxide dismutase, dSOD1, copper-zinc superoxide dismutase, Cu-Zn SOD, Cu[2+]Zn[2+] superoxide dismutase, l(3)68Af', CuZn-superoxide dismutase (SOD)1, CuZn-superoxide dismutase, superoxide dismutatase, super oxide dismutase, ZnSod, CuZn SOD, Superoxide dismutase 1, Cu[2+] Zn[2+] superoxide dismutase, reactive oxygen species metabolic process ; GO:0072593 | IMP, Cu/Zn sod, SOD2, CG11793, paracrine signaling ; GO:0038001 | IMP, copper-zinc superoxide, CuZn-SOD, Tetrazolium oxidase, Cu/Zn superoxide dismutase, superoxide-dismutase, Complementation group G, Cu,Zn Sod, CuZn-SOD1, Mn SOD, l(3)G, Cu,Zn-SOD, l(3)108, SOD, Mn superoxide dismutase, Superoxidase dismutase, tetrazolium oxidase-1, SODC_DROME, sod, superoxide dismutase 1, Cu/ZnSOD, Cu, Zn superoxide dismutase, cytoplasmic Cu/ZnSOD, Sod1, cSod, G, To-1" "IPR018152=Superoxide dismutase, copper/zinc, binding site, IPR001424=Superoxide dismutase, copper/zinc binding domain" CG11793 16-Dec-15 2015_12 ENSDARG00000043848(sod1) YJR104C(SOD1) "WBGene00004930(sod-1),WBGene00007036(sod-5)" ENSXETG00000007350(SOD1) ENSMUSG00000022982(Sod1) ENSG00000142168(SOD1) "viable,chemical sensitive,oxidative stress response defective,male sterile,lethal,recessive,female fertile,reduced,short lived,radiation sensitive,partially,heat sensitive,visible,long lived,chemical conditional,behavior defective,wild-type,electrophoretic variant,partially lethal - majority die,female limited,male limited,calorie restriction conditional,locomotor behavior defective" "adult heart,photoreceptor cell,primary pigment cell,secondary pigment cell,adult brain,trichogen cell" FBgn0053885 His4:CG33885 His4:CG33885 http://flybase.net/reports/FBgn0053885.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33885 "IPR009072=Histone-fold, IPR001951=Histone H4, IPR019809=Histone H4, conserved site" CG33885 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0031866 Nlg2 Neuroligin 2 http://flybase.net/reports/FBgn0031866.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0042043=neurexin family protein binding, 0004872=receptor activity" "0035176=social behavior, 0045433=male courtship behavior, veined wing generated song production, 0007416=synapse assembly, 0048065=male courtship behavior, veined wing extension, 0007628=adult walking behavior, 0007274=neuromuscular synaptic transmission, 0002121=inter-male aggressive behavior, 0050808=synapse organization, 0051124=synaptic growth at neuromuscular junction, 0060074=synapse maturation" "0045202=synapse, 0009986=cell surface, 0005887=integral component of plasma membrane" "dnlg2, DNlg2, neuroligin 2, CG13772, neuroligin, dnl2, nl2" "IPR002018=Carboxylesterase, type B, IPR019819=Carboxylesterase type B, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG13772 16-Dec-15 2015_12 "ENSDARG00000062376(nlgn3b),ENSDARG00000062581(nlgn3a)" WBGene00006412(nlg-1) "ENSMUSG00000063887(Nlgn1),ENSMUSG00000031302(Nlgn3),ENSMUSG00000051790(Nlgn2)" "ENSG00000146938(NLGN4X),ENSG00000196338(NLGN3),ENSG00000165246(NLGN4Y),ENSG00000169760(NLGN1),ENSG00000169992(NLGN2)" "viable,neuroanatomy defective,neurophysiology defective,fertile,locomotor behavior defective,song defective,behavior defective,courtship behavior defective,male" "embryonic/larval neuromuscular junction,NMJ bouton,presynaptic active zone | supernumerary,subsynaptic reticulum,postsynaptic density,bouton,t-bar,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage,supernumerary | third instar larval stage,synapse | embryonic stage,synapse | larval stage" DRSC03578 IE 1.903573478 -0.243028619 1.739972964 0.428813502 -0.059217772 -0.539347002 FBgn0024208 obk obake http://flybase.net/reports/FBgn0024208.html gene 0035214=eye-antennal disc development 16-Dec-15 2015_12 "visible,recessive" "antenna,second segment of antenna,supernumerary,third segment of antenna,arista,maxillary segment,eye,head & macrochaeta,maxillary palpus,wing vein" FBgn0035917 Zasp66 Z band alternatively spliced PDZ-motif protein 66 http://flybase.net/reports/FBgn0035917.html FBgn0045924 protein_coding_gene "0008157=protein phosphatase 1 binding, 0051371=muscle alpha-actinin binding" "0030239=myofibril assembly, 0007498=mesoderm development" 0030018=Z disc "anon-WO0153538.30, Zasp66, ZASP66, CG6416, Zaps66" "IPR001478=PDZ domain, IPR006643=ZASP, IPR017351=LIM and senescent cell antigen-like-containing domain protein 1" CG6416 16-Dec-15 2015_12 "ENSDARG00000011023(pdlim3a),ENSDARG00000014248,ENSDARG00000019845(pdlim1),ENSDARG00000068973(pdlim4),ENSDARG00000069956(pdlim2),ENSDARG00000056322(ldb3a),ENSDARG00000038267(pdlim5)" "ENSXETG00000001563(pdlim3),ENSXETG00000008826(pdlim1),ENSXETG00000016579(pdlim4),ENSXETG00000003653(ldb3),ENSXETG00000007240(pdlim7),ENSXETG00000019217(enh)" "ENSMUSG00000055044(Pdlim1),ENSMUSG00000031636(Pdlim3),ENSMUSG00000020388(Pdlim4),ENSMUSG00000022090(Pdlim2)" "viable,fertile,lethal,flightless,majority die during pupal stage,partially lethal" "indirect flight muscle,myofibril, with Dcr-2UAS.cDa, Mef2.PR,Z disc, with Dcr-2UAS.cDa, Mef2.PR,M band, with Dcr-2UAS.cDa, Mef2.PR,Z discMef2.PR" FBgn0000119 arr arrow http://flybase.net/reports/FBgn0000119.html "FBgn0022055, FBgn0025707, FBgn0033841, FBgn0040307" protein_coding_gene "0005041=low-density lipoprotein receptor activity, 0017147=Wnt-protein binding, 0042813=Wnt-activated receptor activity" "0044332=Wnt signaling pathway involved in dorsal/ventral axis specification, 0060070=canonical Wnt signaling pathway, 0007616=long-term memory, 0001745=compound eye morphogenesis, 0016055=Wnt signaling pathway, 0048076=regulation of compound eye pigmentation, 0006622=protein targeting to lysosome, 0007399=nervous system development" "0005769=early endosome, 0005770=late endosome, 0005886=plasma membrane" "CK00539, LDL-related protein 6, CG5912, LRP6, Dm Arrow, LDLR-like, LRP5/6, LRP/Arr, Irp6, LRP5/6/Arrow, l(2)k08131, LRP, Dm Arr, Arr, Arrow, BEST:CK00539, CT15575" "IPR017049=Low density lipoprotein receptor-related protein, 5/6, IPR000033=LDLR class B repeat, IPR011042=Six-bladed beta-propeller, TolB-like, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000742=EGF-like domain" CG5912 16-Dec-15 2015_12 ENSDARG00000006921(lrp5) "ENSXETG00000010024(LRP5),ENSXETG00000008917(LRP6)" "ENSMUSG00000030201(Lrp6),ENSMUSG00000024913(Lrp5)" "ENSG00000070018(LRP6),ENSG00000162337(LRP5)" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,cell lethal,partially,somatic clone,planar polarity defective,visible,cell non-autonomous,increased cell death,cell growth defective,viable,memory defective,RU486 conditional,partially lethal - majority die,some die during pupal stage" "macrochaeta,midgut constriction 2,gastric caecum,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,eye,head,cuticle,photoreceptor cell,somatic clone,eye disc,embryonic/first instar larval cuticle,denticle,embryonic epidermis,ommatidium,denticle belt,wing,wing margin bristle,ectopic,interommatidial bristle,maternal effect,retina,wing disc,secondary pigment cell,tertiary pigment cell,wing sensillum" FBgn0040623 Spase12 Spase 12-subunit http://flybase.net/reports/FBgn0040623.html FBgn0051042 protein_coding_gene 0008233=peptidase activity 0006465=signal peptide processing "0005787=signal peptidase complex, 0016021=integral component of membrane" "CG31042, CG11500, spase12" IPR009542=Microsomal signal peptidase 12kDa subunit CG11500 16-Dec-15 2015_12 ENSDARG00000059298(spcs1) WBGene00016395(C34B2.10) ENSXETG00000013668(SPCS1) ENSMUSG00000021917(Spcs1) ENSG00000114902(SPCS1) "lethal - all die during embryonic stage,recessive,visible,somatic clone,planar polarity defective,melanotic mass phenotype" "eye,somatic clone,leg,antenna,melanotic mass,ommatidium,interommatidial bristle" FBgn0004561 Su(var)321 Suppressor of variegation 321 http://flybase.net/reports/FBgn0004561.html gene Su(var)231 16-Dec-15 2015_12 "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0065339 l(2)SH1838 lethal (2) SH1838 http://flybase.net/reports/FBgn0065339.html gene l(2)SH2 1838 16-Dec-15 2015_12 "lethal,recessive" FBgn0013352 Antp::Ubx Antp::Ubx http://flybase.net/reports/FBgn0013352.html engineered_fusion_gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "Keilin's organ,mesothoracic tracheal pit,metathoracic tracheal pit,metathoracic ventral denticle belt,denticle belt,embryonic/first instar larval cuticle" FBgn0028310 l(1)G0369 lethal (1) G0369 http://flybase.net/reports/FBgn0028310.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0053876 His2B:CG33876 His2B:CG33876 http://flybase.net/reports/FBgn0053876.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33876 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000558=Histone H2B" CG33876 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0000636 Fas3 Fasciclin 3 http://flybase.net/reports/FBgn0000636.html protein_coding_gene "0016200=synaptic target attraction, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007611=learning or memory, 0007411=axon guidance, 0007476=imaginal disc-derived wing morphogenesis, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0008355=olfactory learning, 0008039=synaptic target recognition, 0007409=axonogenesis, 0007413=axonal fasciculation, 0030707=ovarian follicle cell development" "0005918=septate junction, 0005920=smooth septate junction, 0016323=basolateral plasma membrane, 0016021=integral component of membrane, 0031965=nuclear membrane, 0031594=neuromuscular junction, 0055037=recycling endosome, 0005886=plasma membrane, 0016328=lateral plasma membrane, 0005829=cytosol, 0005737=cytoplasm" "FsciclinIII, Fasiclin III, Fas-III, Fasciclin-3, Fas-3, fasIII, fasciclin III, FascIII, FasciclinIII, fascilin III, Fas III, Fasciclin-III, Fasciclin3, fas3, Fasciclin, Fasicilin III, Fasciclin III, Fascicilin III, fasciclinIII, fasciclin3, fascIII, fasciclin 3, Fasiciclin III, FAS3, CG5803, fas-III, FasIIIface, FAS III, Fas, fas III, FasIII, FASIII, Fascilin III, fasiclin III" "IPR013783=Immunoglobulin-like fold, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain" CG5803 16-Dec-15 2015_12 "ENSDARG00000035158(LOC566921),ENSDARG00000005368(mcamb)" " embryonic stage | stage 12 , adult stage , adult stage && oogenesis stage , embryonic stage | stage 15-17 , embryonic stage " " visceral mesoderm

, germarium && follicle cell

, polar follicle cell

, RP3 neuron

, embryonic/larval visceral muscle

" "lethal,memory defective,neuroanatomy defective,viable,recessive,behavior defective,visible,partially lethal - majority die,some die during pupal stage" "aCC neuron,abdominal segmental nerve,RP3 motor neuron,abdominal 2 ventral longitudinal muscle 3,abdominal 3 ventral longitudinal muscle 3,abdominal 4 ventral longitudinal muscle 3,abdominal 5 ventral longitudinal muscle 3,abdominal 6 ventral longitudinal muscle 3,abdominal 7 ventral longitudinal muscle 3,abdominal 2 ventral longitudinal muscle 4,abdominal 3 ventral longitudinal muscle 4,abdominal 4 ventral longitudinal muscle 4,abdominal 5 ventral longitudinal muscle 4,abdominal 6 ventral longitudinal muscle 4,abdominal 7 ventral longitudinal muscle 4,RP3 neuron & growth cone,abdominal ventral muscle,dorsal appendage,maternal effect,trichogen cell,mesothoracic tergum" FBgn0024188 san separation anxiety http://flybase.net/reports/FBgn0024188.html FBgn0033626 protein_coding_gene "0008080=N-acetyltransferase activity, 0004402=histone acetyltransferase activity, 0005504=fatty acid binding" "0046331=lateral inhibition, 0007067=mitotic nuclear division, 0048812=neuron projection morphogenesis, 0007064=mitotic sister chromatid cohesion" "0008280=cohesin core heterodimer, 0031248=protein acetyltransferase complex, 0005737=cytoplasm" "DmAAF34715, span, CG12352, Complementation group 2, atado, NAA50, sanpodo" "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG12352 16-Dec-15 2015_12 ENSDARG00000027825(naa50) WBGene00018238(F40F4.7) ENSXETG00000009909(Q5XGA9_XENTR) ENSMUSG00000022698(Naa50) ENSG00000121579(NAA50) "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,mitotic cell cycle defective,immune response defective,viable,visible" "embryonic/larval brain,imaginal disc,nucleus | embryonic stage 4 | germline clone,SO0000340chromosome | embryonic stage 4 | germline clone,chromosome & larval neuroblast,somatic clone,follicle cell,mitotic cell cycle,mitosis & nuclear chromosome,chaeta,trichogen cell,tormogen cell" DRSC07695 K 1.001119951 0.111055785 0.322090571 -0.275285957 0.565148296 1.761717976 FBgn0060514 l(3)S103914b lethal (3) S103914b http://flybase.net/reports/FBgn0060514.html gene 1039/14 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005734 l(1)TK219 lethal (1) TK219 http://flybase.net/reports/FBgn0005734.html gene l219 16-Dec-15 2015_12 "lethal,recessive" FBgn0013531 MED20 Mediator complex subunit 20 http://flybase.net/reports/FBgn0013531.html "FBgn0031983, FBgn0042121" protein_coding_gene "0001104=RNA polymerase II transcription cofactor activity, 0003713=transcription coactivator activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter" "0016592=mediator complex, 0005634=nucleus" "med20, Transcription mediator-related, Med20, Trf-proximal, Mediator, Trfp, CG18780, dTrap26, Srb2/TRFP, lethal(2)28DE, CG18267, TrfP, dTrfp, l(2)28DE, p29, Tmr" "IPR013921=Mediator complex, subunit Med20" CG18780 16-Dec-15 2015_12 ENSDARG00000046006(med20) WBGene00007020(mdt-20) ENSXETG00000011847(MED20) ENSMUSG00000073387(Med20) ENSG00000124641(MED20) spermatogenesis && adult stage " testis

, spermatocyte

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069134 mcl(3)Z6259 mcl(3)Z6259 http://flybase.net/reports/FBgn0069134.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0002930 nec necrotic http://flybase.net/reports/FBgn0002930.html "FBgn0024292, FBgn0028676, FBgn0033148, FBgn0063807" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0019732=antifungal humoral response, 0006952=defense response, 0010951=negative regulation of endopeptidase activity, 0006955=immune response, 0045751=negative regulation of Toll signaling pathway, 0009620=response to fungus, 0030162=regulation of proteolysis, 0008063=Toll signaling pathway" 0005615=extracellular space "CG1857, Spn43Ac, serpin43Ac, Ser3, SER3, NEC, Necrotic, Serine protease inhibitor 3, Nec, necrotic serpin, anon-WO0118057.3" "IPR023795=Serpin, conserved site, IPR023796=Serpin domain, IPR000215=Serpin family" CG1857 16-Dec-15 2015_12 "wild-type,short lived,heat sensitive,partially lethal - majority live,lethal,recessive,visible,melanotic necrosis,female sterile,some die during immature adult stage,non-enhancer of variegation,non-suppressor of variegation" "joint,adult integumentary system,adult epidermis,adult abdomen,adult cuticle" FBgn0028516 ZnT35C Zinc transporter 35C http://flybase.net/reports/FBgn0028516.html FBgn0027920 protein_coding_gene "0046873=metal ion transmembrane transporter activity, 0005385=zinc ion transmembrane transporter activity" "0006812=cation transport, 0010043=response to zinc ion, 0055085=transmembrane transport" "0016021=integral component of membrane, 0005622=intracellular, 0016324=apical plasma membrane" "dZnT35C, cg3994, CG3994, BG:DS07295.1" "IPR027469=Cation efflux protein transmembrane domain, IPR002524=Cation efflux protein" CG3994 16-Dec-15 2015_12 "ENSDARG00000021305(slc30a2),ENSDARG00000057629" WBGene00011821(cdf-2) ENSXETG00000009196(Q6DF59_XENTR) ENSMUSG00000022315(Slc30a8) ENSG00000158014(SLC30A2) "chemical resistant,viable,chemical sensitive,melanotic mass phenotype" melanotic mass FBgn0003545 sub subito http://flybase.net/reports/FBgn0003545.html "FBgn0013911, FBgn0034273" protein_coding_gene "0008017=microtubule binding, 0003774=motor activity, 0003777=microtubule motor activity, 0005524=ATP binding" "0051257=meiotic spindle midzone assembly, 0000278=mitotic cell cycle, 0007018=microtubule-based movement, 0000212=meiotic spindle organization, 0007091=metaphase/anaphase transition of mitotic cell cycle, 0016321=female meiosis chromosome segregation, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division" "0005875=microtubule associated complex, 0051233=spindle midzone, 0005873=plus-end kinesin complex, 0005871=kinesin complex, 0005876=spindle microtubule" "Mklp2, double-or-nothing, KIF20A/B, CG12298, Dub, KIF 20A, DmSub, SUB, mei-1794, Double or nothing, Sub, subito, DmKlp54E, Subito" "IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12298 16-Dec-15 2015_12 "ENSDARG00000044491(LOC325449),ENSDARG00000010332(zgc:56231),ENSDARG00000040110,ENSDARG00000071009" "female sterile,recessive,lethal,maternal effect,mitotic cell cycle defective,meiotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,female fertile,reduced,visible,dominant,heat sensitive,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,viable" "spindle,spindle & oocyte,brain,spindle microtubule | larval stage,spindle pole & oocyte,karyosome,spindlePclXM82),chromosome, centromeric regionPC4),eye,wing,wing margin,heat sensitive,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,macrochaeta,spindle midzone & oocyte,chaeta,supernumerary,trichogen cell,spindle microtubule & oocytenos.UTR.THsimVP16,spindle microtubule & stage S14 oocytenos.UTR.THsimVP16,spindle | ectopicnos.UTR.THsimVP16,oocyte" FBgn0053898 His2B:CG33898 His2B:CG33898 http://flybase.net/reports/FBgn0053898.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33898 "IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33898 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053908 His2B:CG33908 His2B:CG33908 http://flybase.net/reports/FBgn0053908.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33908 "IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33908 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053899 His4:CG33899 His4:CG33899 http://flybase.net/reports/FBgn0053899.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33899 "IPR019809=Histone H4, conserved site, IPR001951=Histone H4, IPR009072=Histone-fold" CG33899 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0053887 His4:CG33887 His4:CG33887 http://flybase.net/reports/FBgn0053887.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33887 "IPR009072=Histone-fold, IPR001951=Histone H4, IPR019809=Histone H4, conserved site" CG33887 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0026620 tacc transforming acidic coiled-coil protein http://flybase.net/reports/FBgn0026620.html protein_coding_gene "0005515=protein binding, 0008017=microtubule binding" "0008104=protein localization, 0007279=pole cell formation, 0007344=pronuclear fusion, 0007097=nuclear migration, 0000226=microtubule cytoskeleton organization, 0007143=female meiotic division, 0007026=negative regulation of microtubule depolymerization, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0035046=pronuclear migration" "0000235=astral microtubule, 0005813=centrosome, 0000242=pericentriolar material, 0005875=microtubule associated complex, 0005876=spindle microtubule, 0000922=spindle pole" "TACCdm, D-TACC, acc, CG9765, D-tacc, D. melanogaster transforming acidic coiled coil, dTACC, dtacc, Drosophila Transforming Acidic Coiled-Coil protein, DTACC, d-tacc, transforming acidic coiled-coil, TACC, Drosophila transforming acidic coiled-coil" IPR007707=Transforming acidic coiled-coil CG9765 16-Dec-15 2015_12 "ENSDARG00000005454(tacc3),ENSDARG00000062790" ENSMUSG00000037313(Tacc3) embryonic stage organism

"mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,female sterile" "astral microtubule,centrosome | ectopic,spindle & oocyte,embryonic/larval salivary gland,spindle,aster,mitotic cell cycle,nucleus | embryonic stage,microtubule,pericentriolar material,centrosome,pronucleus,oocyte & spindle110),pole cell" DRSC12388 K -0.164039046 0.566755502 -0.196411409 0.731475413 1.941975919 -0.013831568 FBgn0062581 Mod(var)242 Mod(var)242 http://flybase.net/reports/FBgn0062581.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 242 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,lethal,recessive" FBgn0017571 Mow Modifier of white http://flybase.net/reports/FBgn0017571.html gene mow 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,suppressor of variegation,lethal" pigment cell FBgn0002696 mdg midgoid http://flybase.net/reports/FBgn0002696.html gene 16-Dec-15 2015_12 "visible,recessive,male sterile,viable,male,reduced,body color defective" FBgn0035520 CG11586 http://flybase.net/reports/FBgn0035520.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" "0000398=mRNA splicing, via spliceosome" "IPR022755=Zinc finger, double-stranded RNA binding, IPR003604=Zinc finger, U1-type, IPR015880=Zinc finger, C2H2-like" CG11586 16-Dec-15 2015_12 ENSDARG00000004956(zmat2) YDL098C(SNU23) WBGene00022794(ZK686.4) ENSXETG00000016118(ZMAT2) ENSMUSG00000001383(Zmat2) ENSG00000146007(ZMAT2) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0052423 shep alan shepard http://flybase.net/reports/FBgn0052423.html "FBgn0027668, FBgn0035595, FBgn0035597, FBgn0035599, FBgn0046389, FBgn0062176, FBgn0062425, FBgn0063142" protein_coding_gene "0003723=RNA binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0009629=response to gravity, 0016322=neuron remodeling, 0007552=metamorphosis, 0034976=response to endoplasmic reticulum stress, 0008344=adult locomotory behavior, 0042332=gravitaxis, 0008050=female courtship behavior" 0005829=cytosol "Shep, alan, BcDNA:LD40028, cg10668, anon-WO0118547.198, CG32423, alan shepard, anon-WO0172774.41, BcDNA:RH63980, CG10649, alan-shepard, anon-EST:Posey83, CG10647, CG10668" "IPR002343=Paraneoplastic encephalomyelitis antigen, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG32423 16-Dec-15 2015_12 "ENSDARG00000044179,ENSDARG00000056150(zgc:100836),ENSDARG00000044574(rbms3)" "ENSXETG00000021787(),ENSXETG00000016204(RBMS1)" "ENSMUSG00000040043(Rbms2),ENSMUSG00000026970(Rbms1),ENSMUSG00000039607(Rbms3)" "ENSG00000144642(RBMS3),ENSG00000076067(RBMS2),ENSG00000153250(RBMS1)" "viable,gravitaxis defective,fertile,lethal" DRSC09765 E 0.185809986 0.84776836 -0.533988261 1.687702344 0.264859607 -0.044039804 FBgn0003677 Tcr Third chromosome ë± methyl dopa-resistant http://flybase.net/reports/FBgn0003677.html gene "Third chromosome resistant, l(3)Tcr, Third chromosome resistance" 16-Dec-15 2015_12 "chemical resistant,dominant,lethal,recessive,uncoordinated" FBgn0042134 Capr Caprin http://flybase.net/reports/FBgn0042134.html "FBgn0046032, FBgn0062143" protein_coding_gene 0003723=RNA binding "0045571=negative regulation of imaginal disc growth, 0007349=cellularization, 0009794=regulation of mitotic cell cycle, embryonic" "0030529=ribonucleoprotein complex, 0005811=lipid particle, 0005829=cytosol, 0005737=cytoplasm" "dFAP, dFMRP-associated protein, anon-WO0118547.253, NEST:bs19b07, CG18811" IPR028816=Caprin CG18811 16-Dec-15 2015_12 "ENSDARG00000009346(caprin1a),ENSDARG00000054272(caprin1b),ENSDARG00000020749(caprin2)" "ENSXETG00000003985(m11s1),ENSXETG00000007516(CAPRIN2)" ENSMUSG00000030309(Caprin2) ENSG00000110888(CAPRIN2) "size defective,somatic clone,somatic clone - Minute background,nutrition conditional,viable,mitotic cell cycle defective,maternal effect,fertile,visible,partially lethal - majority die,some die during pupal stage" "ommatidium,somatic clone,somatic clone - Minute background,trichogen cell" FBgn0052594 be ben http://flybase.net/reports/FBgn0052594.html "FBgn0019865, FBgn0030601, FBgn0030602, FBgn0043007" protein_coding_gene "0007274=neuromuscular synaptic transmission, 0007616=long-term memory" "CG32594, anon-EST:CL1a5, ben, E protein, CG15026, CG5530, E, BEST:LD10566, Gene A" IPR011050=Pectin lyase fold/virulence factor CG32594 16-Dec-15 2015_12 " embryonic stage | stage >5 , embryonic stage | stage 5 , embryonic stage | stage 11 , embryonic stage | stage 8 , embryonic stage " " mesoderm

, mesoderm anlage

, mesectoderm

, head

, vitellophage

, yolk

" "neuroanatomy defective,viable,lethal,recessive,memory defective,neurophysiology defective" synapse FBgn0260814 EY04392 http://flybase.net/reports/FBgn0260814.html gene 16-Dec-15 2015_12 "neuroanatomy defective,visible" "embryonic/larval central nervous system,neurite | pharate adult stage,adult brain,adult central nervous system,wing" FBgn0016716 Reg-20 Rhythmically expressed gene 20 http://flybase.net/reports/FBgn0016716.html gene "Drosophila Rhythmically expressed gene 20, Dreg-20" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " adult head

FBgn0015291 Sebp1 Secretion enhancer-binding protein 1 http://flybase.net/reports/FBgn0015291.html gene 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding "0006355=regulation of transcription, DNA-templated" 0005634=nucleus 16-Dec-15 2015_12 larval stage | third instar embryonic/larval salivary gland

FBgn0000212 brm brahma http://flybase.net/reports/FBgn0000212.html FBgn0036554 protein_coding_gene "0003713=transcription coactivator activity, 0016887=ATPase activity, 0008094=DNA-dependent ATPase activity, 0005524=ATP binding, 0042393=histone binding, 0005515=protein binding" "0008587=imaginal disc-derived wing margin morphogenesis, 0006909=phagocytosis, 0006357=regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0043044=ATP-dependent chromatin remodeling, 0048477=oogenesis, 0035329=hippo signaling, 0043974=histone H3-K27 acetylation, 0036335=intestinal stem cell homeostasis, 0007406=negative regulation of neuroblast proliferation, 0048096=chromatin-mediated maintenance of transcription, 0045893=positive regulation of transcription, DNA-templated, 0070983=dendrite guidance, 0045742=positive regulation of epidermal growth factor receptor signaling pathway, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0007409=axonogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0022008=neurogenesis, 0035172=hemocyte proliferation, 2000648=positive regulation of stem cell proliferation, 0048666=neuron development, 0048813=dendrite morphogenesis, 0045088=regulation of innate immune response, 0008586=imaginal disc-derived wing vein morphogenesis, 0007474=imaginal disc-derived wing vein specification" "0070604=PBAF complex, 0005634=nucleus, 0035060=brahma complex" "l(3)72Aa, CG5942, BRM, Brm @ Kto, dBRM, BRD, Complementation group 3.5, E(E2F)3A, Brahma, dSNF2, CG18438, Brm" "IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain, IPR018359=Bromodomain, conserved site, IPR001487=Bromodomain, IPR029295=Snf2 ATP coupling domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR006576=BRK domain, IPR014012=Helicase/SANT-associated domain, IPR014978=Glutamine-Leucine-Glutamine, QLQ, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG5942 16-Dec-15 2015_12 "ENSDARG00000004314(LOC100329898),ENSDARG00000008904(smarca2)" "YOR290C(SNF2),YIL126W(STH1)" WBGene00004204(psa-4) ENSXETG00000009355(SMARCA4) "ENSMUSG00000032187(Smarca4),ENSMUSG00000024921(Smarca2)" "ENSG00000127616(SMARCA4),ENSG00000080503(SMARCA2)" ", adult stage | female , embryonic stage--pupal stage " unfertilized egg

" larval stage , larval stage | third instar " " larval salivary gland

, ventral thoracic disc

, dorsal mesothoracic disc

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,visible,viable,fertile,lethal,enhancer of variegation,dominant,male,homeotic,somatic clone,cell shape defective,wild-type,increased cell size,lethal - all die before end of P-stage,partially,some die during pharate adult stage,heat sensitive,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" "dendritic arborizing neuron,axon,dendrite,wing,eye,ommatidium,macrochaeta,abdominal segment 6,mechanosensory chaeta & adult head | somatic clone,mechanosensory chaeta & adult thorax | somatic clone,mechanosensory chaeta & adult abdomen | somatic clone,embryonic/larval hemocyte,humeral bristle,adult antennal lobe projection neuron DL1 adPN,somatic clone,adult abdominal segment 6,adult abdominal segment 5,ectopic,photoreceptor cell,eye disc,wing sensillum,wing margin bristle,wing vein,posterior,proximal,wing vein L5,distal,posterior crossvein,sensillum campaniformium,macrochaeta & wing69B,prothoracic leg,sex comb,mechanosensory chaeta,sensillum campaniformium & wing69B,thecogen cell,tormogen cell,eo neuron,wing disc | third instar larval stage,capitellum & macrochaeta,haltere,capitellum,wing margin,wing hair,embryonic/larval neuroblast,ganglion mother cell,type II neuroblast,supernumerary" DRSC11330 IEK -0.969023502 -2.462179569 -2.086064123 0.36355782 0.607310471 2.423519817 FBgn0040252 Ugt86Dh Ugt86Dh http://flybase.net/reports/FBgn0040252.html FBgn0037869 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "AC 006491H, CG4772" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG4772 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0029768 SPR Sex peptide receptor http://flybase.net/reports/FBgn0029768.html FBgn0029767 protein_coding_gene 0008528=G-protein coupled peptide receptor activity "0045434=negative regulation of female receptivity, post-mating, 0048042=regulation of post-mating oviposition, 0007186=G-protein coupled receptor signaling pathway" "0005886=plasma membrane, 0016021=integral component of membrane" "SPR, CG12731, CG16752, sex peptide receptor" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR019427=7TM GPCR, serpentine receptor class w (Srw), IPR017452=GPCR, rhodopsin-like, 7TM" CG16752 16-Dec-15 2015_12 WBGene00009629(sprr-2) "partially lethal - majority die,some die during pupal stage,courtship behavior defective,female,behavior defective,viable,mating behavior defective" DRSC18114 K 0.874683259 0.44488452 -0.077779679 0.333115431 -0.594402872 -1.591679647 FBgn0002989 okr okra http://flybase.net/reports/FBgn0002989.html FBgn0017554 protein_coding_gene "0005524=ATP binding, 0004003=ATP-dependent DNA helicase activity" "0006338=chromatin remodeling, 0048477=oogenesis, 0045003=double-strand break repair via synthesis-dependent strand annealing, 0000724=double-strand break repair via homologous recombination, 0006281=DNA repair, 0046843=dorsal appendage formation, 0006310=DNA recombination, 0030261=chromosome condensation, 0007131=reciprocal meiotic recombination, 0008298=intracellular mRNA localization, 0006302=double-strand break repair, 0006417=regulation of translation, 0010212=response to ionizing radiation" "RAD54, Okr, DmRad54, Rad54, Okra, CG3736, DhR54, DmRAD54, Ras54, rad54, Dmrad54, RAD54L, okra" "IPR000330=SNF2-related, N-terminal domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG3736 16-Dec-15 2015_12 ENSDARG00000018623 YGL163C(RAD54) WBGene00004298(rad-54) ENSXETG00000004369(rad54l) ENSMUSG00000028702(Rad54l) ENSG00000085999(RAD54L) " oogenesis stage , oogenesis stage && adult stage | female , embryonic stage--pupal stage " ovary

"wild-type,viable,female fertile,reduced,female sterile,chemical sensitive,recessive,radiation sensitive,male fertile,maternal effect,sterile,fertile,meiotic cell cycle defective,rescuable maternal effect,DNA repair defective" "eye disc,conditional,metaphase & condensed nuclear chromosome | conditional qualifier,presumptive oocyte,karyosome,dorsal appendage,chorion | maternal effect,chorion,nucleus,egg,oocyte,micropyle,follicle cell" FBgn0027088 Aats-gly Glycyl-tRNA synthetase http://flybase.net/reports/FBgn0027088.html FBgn0036477 protein_coding_gene "0004820=glycine-tRNA ligase activity, 0005524=ATP binding" "0006426=glycyl-tRNA aminoacylation, 0048813=dendrite morphogenesis, 0035167=larval lymph gland hemopoiesis" "0005737=cytoplasm, 0005739=mitochondrion" "GRS, dGars, team, CG6778, Gars, terminal arbors missing, GARS, gars, glycyl-tRNA synthetase, GlyRS, Aat-gly" "IPR004154=Anticodon-binding, IPR027031=Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR009068=S15/NS1, RNA-binding, IPR000738=WHEP-TRS domain, IPR002314=Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR002315=Glycyl-tRNA synthetase" CG6778 16-Dec-15 2015_12 ENSDARG00000059070(si:dkey-276i5.1) "YBR121C(GRS1),YPR081C(GRS2)" WBGene00001744(gars-1) ENSXETG00000018474(gars) ENSMUSG00000029777(Gars) ENSG00000106105(GARS) embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "neuroanatomy defective,somatic clone,lethal,partially lethal - majority live,viable,partially lethal - majority die,majority die during P-stage,gravitaxis defective,progressive,neurophysiology defective,visible,lethal - all die before end of first instar larval stage,lethal - all die before end of pupal stage" "adult antennal lobe projection neuron DL1 adPN,somatic clone,neuroblast ALad1,gamma Kenyon cell,giant fiber neuron,eye" FBgn0034646 Rae1 Rae1 http://flybase.net/reports/FBgn0034646.html protein_coding_gene 0005515=protein binding "0007283=spermatogenesis, 0051297=centrosome organization, 0006406=mRNA export from nucleus, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0007141=male meiosis I, 0010506=regulation of autophagy, 2000045=regulation of G1/S transition of mitotic cell cycle, 0000278=mitotic cell cycle, 0051726=regulation of cell cycle" "0005635=nuclear envelope, 0005643=nuclear pore, 0005634=nucleus, 0036126=sperm flagellum, 0016006=Nebenkern" "dmrae1, CG9862, rae1" "IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG9862 16-Dec-15 2015_12 ENSDARG00000007196(rae1) YER107C(GLE2) WBGene00003803(npp-17) ENSXETG00000011270(RAE1) ENSMUSG00000027509(Rae1) ENSG00000101146(RAE1) "viable,male sterile,recessive,meiotic cell cycle defective,mitotic cell cycle defective,body size defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,visible" "Nebenkern,primary spermatocyte,onion stage spermatid,elongation stage spermatid,spermatozoon,meiotic spindle,centriole,centrosome,embryonic/larval neuromuscular junction,embryonic/larval somatic muscle,synapse,NMJ bouton,synapseXE-2900),trichogen cell,mesothoracic tergum" FBgn0020057 E(wa)709 E(wa)709 http://flybase.net/reports/FBgn0020057.html gene E709 16-Dec-15 2015_12 eye color defective pigment cell FBgn0069175 mcl(2)Z4635 mcl(2)Z4635 http://flybase.net/reports/FBgn0069175.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile FBgn0028183 l(3)S024135 lethal (3) S024135 http://flybase.net/reports/FBgn0028183.html gene 0241/35 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053803 His3:CG33803 His3:CG33803 http://flybase.net/reports/FBgn0053803.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33803 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG33803 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053839 His3:CG33839 His3:CG33839 http://flybase.net/reports/FBgn0053839.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33839 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG33839 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053863 His3:CG33863 His3:CG33863 http://flybase.net/reports/FBgn0053863.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33863 "IPR000164=Histone H3/CENP-A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33863 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0022023 eIF-3p40 Eukaryotic initiation factor 3 p40 subunit http://flybase.net/reports/FBgn0022023.html FBgn0027910 protein_coding_gene 0003743=translation initiation factor activity "0045747=positive regulation of Notch signaling pathway, 0006413=translational initiation, 0022008=neurogenesis" "0005829=cytosol, 0005852=eukaryotic translation initiation factor 3 complex" "CG9124, eIf3-p44, Q9U9Q4, eIF-3, eIF3-S3, eIF3h, l(2)k09003, BcDNA:GM14618" "IPR000555=JAB1/MPN/MOV34 metalloenzyme domain, IPR027524=Eukaryotic translation initiation factor 3 subunit H" CG9124 16-Dec-15 2015_12 ENSDARG00000036116(eif3hb) WBGene00001231(eif-3.H) ENSXETG00000007407(eif3s3) ENSMUSG00000022312(Eif3h) ENSG00000147677(EIF3H) "lethal,recessive,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "ganglion mother cell,embryonic/larval neuroblast,wing,wing margin bristle" FBgn0003701 thr three rows http://flybase.net/reports/FBgn0003701.html FBgn0015333 protein_coding_gene "0008406=gonad development, 0051298=centrosome duplication, 0007424=open tracheal system development, 0000281=mitotic cytokinesis, 0007443=Malpighian tubule morphogenesis, 0051306=mitotic sister chromatid separation, 0007440=foregut morphogenesis, 0002009=morphogenesis of an epithelium, 0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0007502=digestive tract mesoderm development, 0000070=mitotic sister chromatid segregation, 0008258=head involution, 0007442=hindgut morphogenesis, 0051533=positive regulation of NFAT protein import into nucleus" 0005737=cytoplasm "anch, CG5785, THR, frag1, fragmented gonads 1, Three rows, anarchist, Separase, three row, Thr, ana" CG5785 16-Dec-15 2015_12 " embryonic stage | cellular blastoderm , embryonic stage , larval stage | third instar , embryonic stage | syncytial blastoderm , embryonic stage | stage 13 , embryonic stage | extended germ band , adult stage " "

ubiquitous , ventral nerve cord

, embryonic central nervous system

, embryonic brain | restricted

, embryonic peripheral nervous system

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,mitotic cell cycle defective,heat sensitive,cytokinesis defective,visible,maternal effect,cold sensitive,partially lethal - majority die,some die during pupal stage" "mitosis | embryonic stage,presumptive embryonic/larval peripheral nervous system,gonad,gonadal sheath proper primordium,visceral mesoderm,Malpighian tubule,embryonic/larval foregut,embryonic/larval hindgut,midgut constriction,embryonic head,embryonic epidermis,embryonic/larval trachea,cycle 15 embryo & anaphase & condensed nuclear chromosome,cleavage nucleus,metaphase plate,embryonic/larval esophagus,denticle belt,mitotic cell cycle | embryonic stage,eye,ommatidium,syncytial blastoderm embryo,maternal effect,stage 5 embryo,centrosome | maternal effect,aster | maternal effect,mesothoracic tergum" DRSC07706 E -1.276969475 -0.650594425 0.304746002 -2.971042431 0.164730376 -0.963548781 FBgn0001169 H Hairless http://flybase.net/reports/FBgn0001169.html protein_coding_gene "0003714=transcription corepressor activity, 0005515=protein binding" "0045746=negative regulation of Notch signaling pathway, 0008052=sensory organ boundary specification, 0035019=somatic stem cell maintenance, 0036335=intestinal stem cell homeostasis, 0044719=regulation of imaginal disc-derived wing size, 0016360=sensory organ precursor cell fate determination, 0010941=regulation of cell death, 0008587=imaginal disc-derived wing margin morphogenesis, 0046331=lateral inhibition, 0048190=wing disc dorsal/ventral pattern formation, 0008586=imaginal disc-derived wing vein morphogenesis, 0007219=Notch signaling pathway" 0005634=nucleus "hairless, CG5460, Hairy" CG5460 16-Dec-15 2015_12 " embryonic stage , pupal stage | >16 hr , adult stage && oogenesis stage , embryonic stage | early , pupal stage | early , larval stage | third instar stage 2 " " mesoderm

, embryonic central nervous system

, tormogen cell

, labral segment

, nurse cell

, central nervous system

, posterior embryonic/larval midgut

, head

, epithelial cell &&of dorsal mesothoracic disc

, cephalic furrow

, imaginal disc

, anterior embryonic/larval midgut

, procephalic segment

" "visible,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell death,decreased cell number,somatic clone,heat sensitive,size defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,viable,partially lethal - majority die,some die during pupal stage" "sensory mother cell,eo neuron,thecogen cell,ectopic,tormogen cell,photoreceptor cell,somatic clone,eye,cone cell | pupal stage,eye disc | pupal stage,wing disc,wing blade,wing margin,wing vein,wing margin bristle,eye disc,ommatidium,wing,campaniform sensillum of anterior crossvein,precursor,sensillum campaniformium of dorsal radius,dorsal row & sensory mother cellap-md544,adult cuticle,macrochaeta,heat sensitive,intestinal stem cell,supernumerary,cone cell,microchaeta,wing disc | third instar larval stage,wing vein L5,anterior orbital bristle,ocellar bristle,mesothoracic tergum & macrochaeta | somatic clone,cell autonomous,medial triple row,socket,sense organ,trichogen cell,chaeta,postvertical bristle,occipital bristle,wing vein L2,wing vein L4,neuron,macrochaeta & head,macrochaeta & scutum,scutellar bristle,eo sensory structure,microchaeta & tormogen cell | conditional ts,wing & macrochaeta,wing vein L3,anterior dorsocentral bristle,head bristle,microchaeta & trichogen cell,upper humeral bristle,posterior orbital bristle,posterior vertical bristle,presutural bristle,posterior postalar bristle,posterior crossvein,dorsal hair,microchaeta & scutum,mesothoracic tergum & macrochaeta,macrochaeta & adult head,adult head & microchaeta,sternopleural bristle,interfollicle cell,adult head & macrochaeta,adult thorax & macrochaeta,leg sensillum,adult abdominal sensillum,adult abdominal sensillum & sternite,dorsal mesothoracic disc & cell,head & macrochaeta,scutum & macrochaeta,external sensory organ precursor cell,wing & microchaeta | ectopicen-e16E,embryonic hindgut,haltere,adult thorax,adult thorax & macrochaetaT113,muscle founder cell,embryonic/larval somatic muscle,peripheral nervous system,tracheal branch primordium,mesothoracic tergum" FBgn0020054 E(wa)761 E(wa)761 http://flybase.net/reports/FBgn0020054.html gene E761 16-Dec-15 2015_12 eye color defective pigment cell FBgn0020412 JIL-1 JIL-1 kinase http://flybase.net/reports/FBgn0020412.html "FBgn0003592, FBgn0062055" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0035175=histone kinase activity (H3-S10 specific), 0005524=ATP binding" "0016572=histone phosphorylation, 0031936=negative regulation of chromatin silencing, 0016321=female meiosis chromosome segregation, 0006468=protein phosphorylation, 0000723=telomere maintenance, 0006325=chromatin organization, 0048477=oogenesis, 0051276=chromosome organization" "0005634=nucleus, 0005700=polytene chromosome, 0016456=X chromosome located dosage compensation complex, transcription activating, 0000790=nuclear chromatin, 0000228=nuclear chromosome, 0005703=polytene chromosome puff" "unnamed, JIL, Su-var(3)103, Su(var)3-103, JIL1, anon-WO0118547.379, JIL-1 histone H3S10 kinase, mAb2A, MSK1, 2Ab17, CG6297, JIL-1 histone kinase, Jil1, MSK, Jil-1, Su-var(3)1, IL-1, Suppressor of variegation 3-1, JIL-1 kinase, Su(var)3-1, JIL-1" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR017892=Protein kinase, C-terminal, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG6297 16-Dec-15 2015_12 "ENSDARG00000044436(si:dkey-273o13.5),ENSDARG00000060551(LOC565173)" "ENSG00000100784(RPS6KA5),ENSG00000162302(RPS6KA4)" "viable,modifier of variegation,enhancer of variegation,suppressor of variegation,fertile,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,visible,homeotic,lethal,recessive,meiotic cell cycle defective,dominant,partially lethal - majority die,mitotic cell cycle defective,female sterile,non-suppressor of variegation,wild-type" "polytene chromosome | larval stagehs.PB,intersegmental nerve,abdominal sternite 6,male,abdominal sternite 5,ectopic,ovary,spindle[-],chromatin[-],nucleus[-],polytene chromosome[-],polytene chromosome,polytene chromosome | male,polytene chromosome band | male,euchromatin,polytene chromosome interband,embryonic/larval neuroblast,spindle | third instar larval stage,polytene chromosome | larval stage,egg,ovariole,egg chamber,nurse cell,oocyte nucleus" DRSC11200 I -0.716145845 3.977689898 -0.259961019 1.137845901 0.206385358 -0.21727481 FBgn0038118 timeout timeout http://flybase.net/reports/FBgn0038118.html "FBgn0038116, FBgn0038117, FBgn0038121, FBgn0041714" protein_coding_gene "0009649=entrainment of circadian clock, 0000077=DNA damage checkpoint" "CG14382, CG7855, CG8148, timeless2, CG14381, dtim2, TIM2, tim2, timeless 2" "IPR006906=Timeless protein, IPR007725=Timeless C-terminal" CG7855 16-Dec-15 2015_12 WBGene00006571(tim-1) ENSXETG00000021816(TIMELESS) ENSMUSG00000039994(Timeless) ENSG00000111602(TIMELESS) "lethal - all die before end of P-stage,recessive,some die during P-stage,viable,fertile,locomotor rhythm defective,dominant,lethal - all die before end of pupal stage,some die during pupal stage,visible" "SO0000340chromosome | larval stageExel6167),SO0000340chromosome | larval stage,head,eye,trichogen cell" FBgn0001809 l(1)ml lethal (1) melanomalike http://flybase.net/reports/FBgn0001809.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "melanotic mass,egg chamber,maternal effect" FBgn0005348 sf-3 safranin on 3 http://flybase.net/reports/FBgn0005348.html gene safranin in chromosome 3 16-Dec-15 2015_12 "visible,recessive,eye color defective" pigment cell FBgn0004531 l(4)102CDb lethal (4) 102CDb http://flybase.net/reports/FBgn0004531.html gene "l(4)23, l(4)AM-3" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005636 nvy nervy http://flybase.net/reports/FBgn0005636.html protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0007411=axon guidance, 0007517=muscle organ development, 0008407=chaeta morphogenesis" 0005634=nucleus "Nervy, Nvy, CG3385, nervy" "IPR002893=Zinc finger, MYND-type, IPR013293=Nervy, IPR014896=NHR2-like, IPR003894=TAFH/NHR1, IPR013289=Eight-Twenty-One" CG3385 16-Dec-15 2015_12 "ENSDARG00000003680(runx1t1),ENSDARG00000059898" "ENSXETG00000011259(),ENSXETG00000014592(RUNX1T1),ENSXETG00000021431(CBFA2T2)" "ENSMUSG00000006362(Cbfa2t3),ENSMUSG00000006586(Runx1t1),ENSMUSG00000038533(Cbfa2t2)" "ENSG00000129993(CBFA2T3),ENSG00000079102(RUNX1T1),ENSG00000078699(CBFA2T2)" embryonic stage | stage >=9 " central nervous system | restricted

, embryonic peripheral nervous system | restricted

, neuroblast

" "neuroanatomy defective,lethal,viable" "sensory mother cell,somatic clone,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,lateral longitudinal fascicle,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,abdominal segmental nerve,mechanosensory sensory organ & thoraxpnr-MD237,medial longitudinal fascicle,adult thorax & mechanosensory sensory organ-537.4,adult thorax | dorsal & mechanosensory sensory organpnr-MD237,cell non-autonomous,adult thorax & mechanosensory sensory organ | somatic cloneë±Tub84B.PZ,mechanosensory neuron,thecogen cell,mechanosensory sensory organ,cuticle" DRSC04705 E 1.024897471 0.402026107 2.644289032 0.137988583 -0.121210071 1.06207011 FBgn0027169 l(2)ESH1 lethal (2) ESH1 http://flybase.net/reports/FBgn0027169.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0025172 l(2)38Dd lethal (2) 38Dd http://flybase.net/reports/FBgn0025172.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0082634 S(CycEJP)2.13 S(CycEJP)2.13 http://flybase.net/reports/FBgn0082634.html gene 2.13 16-Dec-15 2015_12 "lethal,recessive" FBgn0260496 l(3)7 http://flybase.net/reports/FBgn0260496.html gene 16-Dec-15 2015_12 neuroanatomy defective dendritic arborizing neuron FBgn0003002 opa odd paired http://flybase.net/reports/FBgn0003002.html protein_coding_gene "0046872=metal ion binding, 0001205=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007494=midgut development, 0008354=germ cell migration, 0007365=periodic partitioning, 0006357=regulation of transcription from RNA polymerase II promoter, 0007455=eye-antennal disc morphogenesis, 0008101=decapentaplegic signaling pathway" 0005634=nucleus "CG1133, odd-paired, Opa, Odd-paired, Odd paired, GLI-Kr zinc finger pair-rule protein" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1133 16-Dec-15 2015_12 "ENSDARG00000016022(zic5),ENSDARG00000031307(zic4),ENSDARG00000071497(zic3),ENSDARG00000015567(zic1),ENSDARG00000015554(zic2a),ENSDARG00000037178(zic2b),ENSDARG00000071496(zic6)" "ENSXETG00000018872(ZIC5),ENSXETG00000015467(ZIC1),ENSXETG00000018864(ZIC2),ENSXETG00000015475(ZIC4),ENSXETG00000024458(TGas128g07.1)" "ENSMUSG00000061524(Zic2),ENSMUSG00000032368(Zic1),ENSMUSG00000067860(Zic3),ENSMUSG00000036972(Zic4),ENSMUSG00000041703(Zic5)" "ENSG00000043355(ZIC2),ENSG00000152977(ZIC1),ENSG00000156925(ZIC3),ENSG00000174963(ZIC4),ENSG00000139800(ZIC5)" " embryonic stage | stage 6 , embryonic stage | stage 5 , embryonic stage | stage 7 , embryonic stage | stage 11-12 , embryonic stage | stage 5,6 , embryonic stage--pupal stage , embryonic stage | stage 13-17 " " mesoderm

, organism | 10-80% egg length

, organism | striped

, visceral mesoderm

,

20-80% egg length , organism | 80% egg length

, visceral mesoderm &&of parasegment 9--12

, parasegment 5 &&of visceral mesoderm

, ectoderm

" " embryonic stage | stage 5-7 , embryonic stage | stage 7 " "

20-80% egg length , organism | striped

" "visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,heat sensitive,pair rule phenotype" "heart primordium,adult head,somatic clone,ventral,eye,rostral membrane,vibrissae,maxillary palpus,antenna,heat sensitive,gena,denticle belt,embryonic segment,midgut constriction,embryonic/first instar larval cuticle,embryonic maxillary segment,gonadal sheath proper primordium,fat body/gonad primordium,embryonic/larval cuticle,eye disc,antennal disc,arista,supernumerary,adult antennal segment" DRSC26411 K -0.960754575 -0.001004104 -0.145380117 0.055374035 -0.453412534 1.948458852 FBgn0035147 Gale UDP-galactose 4'-epimerase http://flybase.net/reports/FBgn0035147.html protein_coding_gene "0003974=UDP-N-acetylglucosamine 4-epimerase activity, 0003978=UDP-glucose 4-epimerase activity" "0006012=galactose metabolic process, 0035167=larval lymph gland hemopoiesis" "UDP-gal 4' epimerase, GALE, dGALE, CG12030" "IPR005886=UDP-glucose 4-epimerase GalE, IPR016040=NAD(P)-binding domain, IPR008089=Nucleotide sugar epimerase" CG12030 16-Dec-15 2015_12 ENSDARG00000002401(gale) WBGene00008132(gale-1) ENSXETG00000001170(gale) ENSMUSG00000028671(Gale) ENSG00000117308(GALE) "lethal,recessive,small body,germline clone,viable,chemical sensitive,short lived,chemical conditional,temperature conditional,sterile,heat sensitive,partially lethal - majority die,body color defective" mesothoracic tergum FBgn0001301 kel kelch http://flybase.net/reports/FBgn0001301.html protein_coding_gene 0003779=actin binding "0007297=ovarian follicle cell migration, 0007303=cytoplasmic transport, nurse cell to oocyte, 0048477=oogenesis, 0007300=ovarian nurse cell to oocyte transport, 0007301=female germline ring canal formation, 0030717=karyosome formation, 0007349=cellularization, 0030036=actin cytoskeleton organization, 0030723=ovarian fusome organization" "0035324=female germline ring canal, 0045172=germline ring canal, 0005938=cell cortex, 0035183=female germline ring canal inner rim" "CG7210, kelch, Kelch, Kel, Dm.Ring_canal/KELC_DROME" "IPR015916=Galactose oxidase, beta-propeller, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR006652=Kelch repeat type 1, IPR011705=BTB/Kelch-associated" CG7210 16-Dec-15 2015_12 " oogenesis stage && adult stage | female , adult stage | male , adult stage | female " ovary

" adult stage && oogenesis stage , pupal stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >S1 , larval stage | third instar , adult stage " " egg chamber

, ovary

, germarium region 3 && nurse cell ring canal

, nurse cell ring canal

, imaginal disc

, testis

, ring canal

" "female sterile,recessive,increased cell death,cell shape defective,wild-type" "nurse cell ring canal,egg chamber,nurse cell,nurse cell & actin filament,oocyte & actin filament,nurse cell ring canal rim,oocyte,interfollicle cell,nurse cell fusome,karyosome,nurse cell & nucleus,actin filament,filamentous actin,actin filament & nurse cell ring canal,egg,nurse cell & plasma membrane,inner nurse cell ring canal rim" FBgn0027568 Cand1 Cullin-associated and neddylation-dissociated 1 http://flybase.net/reports/FBgn0027568.html protein_coding_gene "0005515=protein binding, 0008134=transcription factor binding" "2000435=negative regulation of protein neddylation, 0031647=regulation of protein stability" "BcDNA:GH07774, CG5366, Cullin-associated and neddylation-dissociated 1, Cand1, dmCAND1, CAND1" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR013932=TATA-binding protein interacting (TIP20)" CG5366 16-Dec-15 2015_12 "ENSDARG00000017841(cand1),ENSDARG00000005749(si:dkey-72g22.1)" WBGene00013606(cand-1) "ENSXETG00000007328(cand1),ENSXETG00000001455(CAND2)" "ENSMUSG00000020114(Cand1),ENSMUSG00000030319(Cand2)" ENSG00000111530(CAND1) "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0000739 fs(1)A117 female sterile (1) A117 http://flybase.net/reports/FBgn0000739.html gene 16-Dec-15 2015_12 "female semi-sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,embryo" FBgn0259529 GG01317 http://flybase.net/reports/FBgn0259529.html gene 16-Dec-15 2015_12 visible wing FBgn0261786 mi minus http://flybase.net/reports/FBgn0261786.html "FBgn0002743, FBgn0034873, FBgn0065616" protein_coding_gene "0008284=positive regulation of cell proliferation, 0007113=endomitotic cell cycle, 0007300=ovarian nurse cell to oocyte transport, 0045931=positive regulation of mitotic cell cycle, 0051726=regulation of cell cycle, 0040018=positive regulation of multicellular organism growth, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation" "CG5360, l(2)SH0818, l(2)SH2 0818, lethal (2) SH0818" CG5360 16-Dec-15 2015_12 DRSC04498 IK 1.657612351 -1.764990709 -0.614552745 0.378570198 1.509233575 1.77435855 FBgn0038256 CG7530 http://flybase.net/reports/FBgn0038256.html protein_coding_gene 0016021=integral component of membrane IPR004254=AdipoR/Haemolysin-III-related CG7530 16-Dec-15 2015_12 "ENSDARG00000044253(paqr3b),ENSDARG00000017703(paqr3a)" YLR023C(IZH3) WBGene00013457(paqr-3) ENSXETG00000009529(PAQR3) ENSMUSG00000055725(Paqr3) ENSG00000163291(PAQR3) "chemical resistant,viable" FBgn0052177 Ndfip Nedd4 family interacting protein http://flybase.net/reports/FBgn0052177.html "FBgn0025964, FBgn0036744, FBgn0064124" protein_coding_gene 0050699=WW domain binding "0008593=regulation of Notch signaling pathway, 0035220=wing disc development" "0005770=late endosome, 0000151=ubiquitin ligase complex" "dNdfip, CG32177, clone 2.19, anon-EST:Liang-2.19, unnamed, CG8056" CG32177 16-Dec-15 2015_12 "ENSDARG00000013979(ndfip1),ENSDARG00000008057(ndfip1l),ENSDARG00000033928" "ENSXETG00000019569(NFIP1_XENTR),ENSXETG00000017809(NDFIP2)" "ENSMUSG00000053253(Ndfip2),ENSMUSG00000024425(Ndfip1)" "ENSG00000102471(NDFIP2),ENSG00000131507(NDFIP1)" "viable,fertile" "wing margin bristle,supernumerary,wing vein" FBgn0010114 hig hikaru genki http://flybase.net/reports/FBgn0010114.html protein_coding_gene "0008039=synaptic target recognition, 0007155=cell adhesion" "0043083=synaptic cleft, 0005576=extracellular region, 0043025=neuronal cell body" "CT6282, CG2040, HIG, Hikaru genki" "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR000436=Sushi/SCR/CCP domain, IPR007110=Immunoglobulin-like domain" CG2040 16-Dec-15 2015_12 " embryonic stage , adult stage , embryonic stage | mid-late , embryonic stage | stage >=10 " " RP neuron

, head

, pCC neuron

, central nervous system | restricted

, supraesophageal ganglion

" "viable,fertile,hypoactive,uncoordinated,locomotor behavior defective,lethal,some die during immature adult stage,recessive,flightless,behavior defective,wild-type" central nervous system DRSC22827 E 0.838339721 0.405379199 1.855433716 0.368394615 -0.249686251 -0.241128801 FBgn0000404 CycA Cyclin A http://flybase.net/reports/FBgn0000404.html "FBgn0010826, FBgn0011353, FBgn0044754" protein_coding_gene "0005515=protein binding, 0016538=cyclin-dependent protein serine/threonine kinase regulator activity" "0000086=G2/M transition of mitotic cell cycle, 0046331=lateral inhibition, 0007096=regulation of exit from mitosis, 0022008=neurogenesis, 0009794=regulation of mitotic cell cycle, embryonic, 0000070=mitotic sister chromatid segregation, 0007067=mitotic nuclear division, 0055059=asymmetric neuroblast division, 0007422=peripheral nervous system development, 0045841=negative regulation of mitotic metaphase/anaphase transition, 0035186=syncytial blastoderm mitotic cell cycle, 0035561=regulation of chromatin binding, 0007088=regulation of mitotic nuclear division" "0019908=nuclear cyclin-dependent protein kinase holoenzyme complex, 0045170=spectrosome, 0045169=fusome, 0005737=cytoplasm, 0005634=nucleus" "1329/16, 0033/02, CG5940, CyclinA, 0521/06, S(rux)3B, l(3)68Ea, cyclin A, DmcycA, 0040/24, l(3)183, Suppressor of rux 3B, rose-gespleten region interval 11, rsg11, CYCA, l(3)neo114, 0245/34, 1449/05, anon-WO0140519.128, 0104/07, l(3)j3C8, Cyc A, CLD3, l(3)rsg11, l(3)03946, 0545/13, cycA, dCycA, 0046/23, hari, cyclinA" "IPR013763=Cyclin-like, IPR004367=Cyclin, C-terminal domain, IPR006671=Cyclin, N-terminal" CG5940 16-Dec-15 2015_12 ENSDARG00000043236(ccna1) WBGene00013981(ZK507.6) "ENSXETG00000001016(CCNA2),ENSXETG00000013224(ccna1)" "ENSMUSG00000027715(Ccna2),ENSMUSG00000027793(Ccna1)" "ENSG00000133101(CCNA1),ENSG00000145386(CCNA2)" " oogenesis stage | stage S9-10 && adult stage | female , larval stage , adult stage | female , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage , embryonic stage | early " " nurse cell

, larval brain

, germarium

, ovary

, imaginal disc

, organism

,

ubiquitous " " embryonic stage | early , larval stage , embryonic stage | syncytial blastoderm , embryonic stage " " larval central nervous system

, peripheral nervous system

, imaginal disc

, embryonic central nervous system

" "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during immature adult stage,visible,wild-type,neuroanatomy defective,cell migration defective,viable,reduced" "embryonic/larval dorsal trunk,embryonic/larval transverse connective,ganglion mother cell GMC1-1a,ganglion mother cell GMC4-2a,EL neuron,embryonic epidermis,neuron,mitotic cell cycleprd.RG1,RP2sib neuron,aCC neuron,precursor,pCC neuron,U neuron,larval outer optic anlage,chordotonal organ,neuron & peripheral nervous system,eye,mitotic cell cycle & epidermis & embryo,mitotic cell cycle,egg chamber,S phase | ectopic,amnioserosa,pole cell,egg chamber & cell,egg chamber & mitotic cell cycle,mitotic cell cycle & eye,cell cycle,metaphase & condensed nuclear chromosome,anaphase & condensed nuclear chromosome,embryonic pericardial cell,abdominal segment 2 & cardioblast,abdominal segment 3 & cardioblast,abdominal segment 4 & cardioblast,abdominal segment 5 & cardioblast,abdominal segment 6 & cardioblast,abdominal segment 7 & cardioblast,cardioblast,embryonic/larval glial cell,embryonic/larval tracheal system,embryonic/larval ganglionic branch,embryonic ganglion mother cell,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,neuroblast NB7-3,EW neuron,GW neuron,neuroblast NB6-4 of thorax,neuroblast NB6-4 of abdomen,dorsal neurohemal organ,eye disc,embryonic/larval salivary gland | embryonic stage,nurse cell fusome,S phase | ectopichs.2sev,male germline stem cell,ommatidium,chaeta,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,female germline stem cell,germarium" DRSC11123 IEK -2.114436164 -1.442374368 -0.290036912 -2.217212947 2.826154442 3.090742543 FBgn0000711 flw flapwing http://flybase.net/reports/FBgn0000711.html "FBgn0003131, FBgn0029072, FBgn0030197, FBgn0030198, FBgn0066854" protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0017018=myosin phosphatase activity" "0046329=negative regulation of JNK cascade, 0007059=chromosome segregation, 0006470=protein dephosphorylation, 0007476=imaginal disc-derived wing morphogenesis, 0007301=female germline ring canal formation, 0007300=ovarian nurse cell to oocyte transport, 0007155=cell adhesion, 0031991=regulation of actomyosin contractile ring contraction, 0016203=muscle attachment, 0002168=instar larval development, 0007498=mesoderm development, 0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 0014706=striated muscle tissue development" 0000164=protein phosphatase type 1 complex "protein phosphatase 1, PP1 b9C, flapwing, PP1beta-9C, Flapwing, Protein phosphatase 1beta at 9C, Flap wing, PP-1, anon-WO03040301.120, PP1cbeta, PP1B_DROME, PP1c, Pp1beta-9C, PP1 beta9c, PP1, PP1beta9C, FLW, PP1beta, Pp1beta9C, XE55, CG2096, flap wing, DmPp1-9C, FLW/PP1B, CG15305, l(1)G0172, Pp1-9C, PP1 9C, PP19C" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like" CG2096 16-Dec-15 2015_12 ENSDARG00000044153(ppp1cb) YER133W(GLC7) WBGene00001747(gsp-1) ENSMUSG00000014956(Ppp1cb) ENSG00000213639(PPP1CB) embryonic stage -- adult stage pupal stage "increased cell number,recessive,somatic clone,cell polarity defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,male,female,lethal,lethal - all die before end of pupal stage,wild-type,flightless,dominant,viable,visible,cell shape defective,locomotor behavior defective,partially lethal - majority live,mitotic cell cycle defective,majority die during larval stage,some die during pupal stage,small body" "nurse cell ring canal,germline clone,oocyte,somatic clone,follicle cell,posterior,egg,maternal effect,wing,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,myofibril,Z disc,indirect flight muscle,adult cuticle & adult thorax,epithelium,egg chamber,actin cytoskeleton,mesothoracic extracoxal depressor muscle 66,embryonic/larval muscle system,posterior crossvein,anterior scutellar bristle,eye,tergosternal muscle 47a,tergosternal muscle 47b,tergosternal muscle 47c,dorsal medial muscle 45c,dorsal medial muscle 45d,dorsal medial muscle 45e,dorsal medial muscle 45f,dorsal medial muscle 45a,dorsal medial muscle 45b,adult thorax,chromosome & larval neuroblast,anaphase,ventral intersegmental muscle,eye disc,wing disc" DRSC18774 I 0.563194382 -2.018698823 0.476967334 -0.306611364 1.024617341 0.538164871 FBgn0000147 aurA aurora A http://flybase.net/reports/FBgn0000147.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0004712=protein serine/threonine/tyrosine kinase activity" "0018105=peptidyl-serine phosphorylation, 0051298=centrosome duplication, 0007017=microtubule-based process, 0008105=asymmetric protein localization, 1903827=regulation of cellular protein localization, 0007100=mitotic centrosome separation, 0007098=centrosome cycle, 0045167=asymmetric protein localization involved in cell fate determination, 0051297=centrosome organization, 0006468=protein phosphorylation, 0007279=pole cell formation, 0050767=regulation of neurogenesis, 0051294=establishment of spindle orientation, 0098725=symmetric cell division, 0051299=centrosome separation" "0005737=cytoplasm, 0005813=centrosome" "aurora-A, ck[10], l(3)ck10, aurora, Aurora A kinase, Aurora-A kinase, early-A, AuroraA, l(3)87Ac, aur-A, aur, aurora A, Aurora-A, Aurora A, Aur-A, AurA, A-type Aurora kinase, fruhe2, Aurora, 87A7-9/2, ck10, CG3068, aurA, auroraA, Aurora Kinase" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR030616=Aurora kinase" CG3068 16-Dec-15 2015_12 "ENSDARG00000012485(zgc:100912),ENSDARG00000037640(aurkb)" YPL209C(IPL1) WBGene00000098(air-1) "ENSXETG00000012032(stk6),ENSXETG00000009097(TGas109c10.1)" "ENSMUSG00000027496(Aurka),ENSMUSG00000020897(Aurkb)" "ENSG00000087586(AURKA),ENSG00000178999(AURKB),ENSG00000105146(AURKC)"

"mitotic cell cycle defective,visible,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,recessive,female sterile,viable,wild-type,somatic clone,sterile,lethal,maternal effect,some die during pharate adult stage,endomitotic cell cycle defective,lethal - all die during P-stage,partially lethal - majority die" "spindle,neuroblast,socket,ectopic,somatic clone,trichogen cell,thecogen cell,eo neuron,tormogen cell,sensory mother cell,centrosome,embryonic/larval neuroblast,embryonic/larval brain,mitotic metaphase & larval brainT-47),mitotic metaphase & larval brainT-61),microtubule & neuroblast & larvaT-61),aster & neuroblast & larvaT-61),centrosome & neuroblast & larvaT-61),centriole & neuroblast & larva | ectopicT-61),mitotic metaphase & larval brainP-79),mitotic metaphase & larval brain,centrosome & neuroblast & larva,macrochaeta,eye,egg chamber,neuroblast | supernumerary & larva,neuroblast | supernumerary & larval brain,supernumerary,spindle & neuroblast & larva,spindle & sensory mother cell & pupa,neuroblast | supernumerary & brain,pole cell,centrosome | embryonic stage,nucleus | embryonic stage,mitotic cell cycle,embryonic/larval central nervous system,subperineurial glial cell,metaphase & condensed nuclear chromosome,aster,microtubule | maternal effect" DRSC16905 IE 2.154148415 0.190328205 0.463149751 -2.094677985 -0.892165187 -0.314323816 FBgn0031654 Jon25Bii Jonah 25Bii http://flybase.net/reports/FBgn0031654.html FBgn0001284 protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0022008=neurogenesis" "Jon25, SP112, CG8869, Jonah 25B, Jon25B, 25B" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG8869 16-Dec-15 2015_12 "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" "viable,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" FBgn0041775 tral trailer hitch http://flybase.net/reports/FBgn0041775.html "FBgn0027756, FBgn0036296, FBgn0045828, FBgn0046345, FBgn0066038" protein_coding_gene 0005515=protein binding "0006888=ER to Golgi vesicle-mediated transport, 0000226=microtubule cytoskeleton organization, 0007310=oocyte dorsal/ventral axis specification, 0030036=actin cytoskeleton organization" "0005829=cytosol, 0005783=endoplasmic reticulum, 0005875=microtubule associated complex, 0043186=P granule, 0045169=fusome" "TRAL, p70, Scd6p, Lsm15, CG10686, DmLSm15, Trailer hitch, p67, anon-WO0172774.89, Trailer Hitch, BEST:GH08269, anon-WO02059370.24, Tral, Trailer-Hitch, LSm15, anon-EST:Posey139" "IPR025762=DFDF domain, IPR010920=LSM domain, IPR025761=FFD box, IPR019050=FDF domain, IPR025609=Lsm14 N-terminal, IPR025768=TFG box" CG10686 16-Dec-15 2015_12 "ENSDARG00000011408(zgc:77202),ENSDARG00000006600(lsm14a),ENSDARG00000025386(zgc:55673)" YPR129W(SCD6) "ENSXETG00000002359(Q6NVR8_XENTR),ENSXETG00000001997(FA61B_XENTR)" "ENSMUSG00000039108(Lsm14b),ENSMUSG00000066568(Lsm14a)" "ENSG00000105216(LSM14A),ENSG00000149657(LSM14B)" "lethal,female sterile,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,maternal effect,chorion | anterior,microtubule & oocyte,cycle 12 embryo,cycle 13 embryo,nurse cell,germline clone,egg,chorion | anterioriro-2)" DRSC09779 EK -0.519761582 -0.449039362 -1.804201807 -5.122807187 1.088618331 4.142742509 FBgn0002471 l(3)SG26 lethal (3) SG26 http://flybase.net/reports/FBgn0002471.html FBgn0004712 gene "l(3)ds-2, l(3)g26, l(3)ds2, l(3)B2" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,imaginal disc primordium,testis,ovary,central nervous system,mitotic cell cycle" FBgn0051371 CG31371 http://flybase.net/reports/FBgn0051371.html FBgn0039781 protein_coding_gene "0004656=procollagen-proline 4-dioxygenase activity, 0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" 0055114=oxidation-reduction process 0005783=endoplasmic reticulum CG15542 "IPR011990=Tetratricopeptide-like helical domain, IPR013547=Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG31371 16-Dec-15 2015_12 viable FBgn0003185 qrt quartet http://flybase.net/reports/FBgn0003185.html FBgn0004728 gene "l(3)CR215, l(3)c21R, l(3)c21r, l(3)C21, l(3)B1, l(3)ds-1, l(3)SG56, l(3)ds1" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,maternal effect,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc,centrosome | maternal effect | heat sensitive,spindle | maternal effect | heat sensitive,mitosis & nuclear chromosome | conditional ts | maternal effect,embryo,nucleus | embryonic stage | maternal effect | heat sensitive" FBgn0026398 Or22a Odorant receptor 22a http://flybase.net/reports/FBgn0026398.html protein_coding_gene "0004888=transmembrane signaling receptor activity, 0004984=olfactory receptor activity, 0005549=odorant binding" "0007608=sensory perception of smell, 0050911=detection of chemical stimulus involved in sensory perception of smell" "0030425=dendrite, 0071683=sensory dendrite, 0016021=integral component of membrane, 0032590=dendrite membrane" "Or53, DOR22a, DOR22A.1, Dmel22a, Dmel Or22a, dor53, dOr22a, DOR53, Dor53, 22a, OR22a, Olfactory receptor 22A.1, DmOr22a, Or22a/b, AN11, Or22A.1, CG12193, Odorant receptor 53, 22A.1" "IPR004117=Olfactory receptor, Drosophila" CG12193 16-Dec-15 2015_12 adult stage sensory neuron &&of antennal segment 3

neurophysiology defective olfactory receptor neuron FBgn0016081 fry furry http://flybase.net/reports/FBgn0016081.html "FBgn0010771, FBgn0036021, FBgn0036025, FBgn0036027, FBgn0052045" protein_coding_gene 0005515=protein binding "0050773=regulation of dendrite development, 0007476=imaginal disc-derived wing morphogenesis, 0048814=regulation of dendrite morphogenesis, 0035316=non-sensory hair organization, 0008407=chaeta morphogenesis, 0016055=Wnt signaling pathway, 0035317=imaginal disc-derived wing hair organization, 0070593=dendrite self-avoidance, 0042052=rhabdomere development, 0045860=positive regulation of protein kinase activity, 0048800=antennal morphogenesis, 0048601=oocyte morphogenesis" "0045177=apical part of cell, 0005938=cell cortex, 0030425=dendrite, 0030424=axon, 0005737=cytoplasm, 0044297=cell body" "RE-B, CG14171, Suppressor of GMR-sina 3-7, Furry, SS3-7, yeti, CG32045, CG6780, l(3)02240, Fry, CG6774" "IPR016024=Armadillo-type fold, IPR025481=Cell morphogenesis protein C-terminal, IPR025614=Cell morphogenesis protein N-terminal, IPR029473=Cell morphogenesis central region" CG32045 16-Dec-15 2015_12 "ENSDARG00000056001(fryb),ENSDARG00000039986" YIL129C(TAO3) WBGene00004728(sax-2) ENSXETG00000004391(FRYL) "ENSMUSG00000056602(Fry),ENSMUSG00000070733(Fryl)" "ENSG00000073910(FRY),ENSG00000075539(FRYL)" "viable,fertile,neuroanatomy defective,visible,lethal,recessive,cell autonomous,somatic clone,lethal - all die before end of larval stage,some die during larval stage,sterile,poor" "multidendritic neuron & dendrite | supernumerary,multidendritic neuron & dendrite,dorsal multidendritic neuron ddaC,arista,wing hair,supernumerary,adult abdomen & chaeta,leg & chaeta,mesothoracic tergum & chaeta,triple row,head bristle,cell autonomous,somatic clone,wing cell,ectopic,ovary,egg,rhabdomere,dendrite | cell autonomous | somatic clone | supernumerary,multidendritic neuron & dendrite | somatic clone,photoreceptor cell & eye disc | somatic clone,follicle cell,actin filament | somatic clone,egg chamber" DRSC10709 K 0.348784729 -0.805535142 -0.35183424 0.22606273 0.863359078 1.691806549 FBgn0011737 Wee1 Wee1 kinase http://flybase.net/reports/FBgn0011737.html FBgn0010519 protein_coding_gene "0004715=non-membrane spanning protein tyrosine kinase activity, 0005524=ATP binding, 0004713=protein tyrosine kinase activity, 0004672=protein kinase activity, 0000287=magnesium ion binding" "0018108=peptidyl-tyrosine phosphorylation, 0051299=centrosome separation, 0051225=spindle assembly, 0001700=embryonic development via the syncytial blastoderm, 0007067=mitotic nuclear division, 0045448=mitotic cell cycle, embryonic, 0051642=centrosome localization, 0000278=mitotic cell cycle, 0000280=nuclear division, 0007093=mitotic cell cycle checkpoint, 0006468=protein phosphorylation, 0045736=negative regulation of cyclin-dependent protein serine/threonine kinase activity" "0005875=microtubule associated complex, 0005634=nucleus" "Wee, Wee1, Wee 1, dWee1, Wee1 kinase, wee, Dwee, Wee1 ortholog (S. pombe), dwee1, CG4488, Dwee1, wee1, WEE1" "IPR017441=Protein kinase, ATP binding site, IPR017164=Wee1-like protein kinase, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG4488 16-Dec-15 2015_12 "ENSDARG00000041587(wee1),ENSDARG00000012718(wee2)" WBGene00006938(wee-1.1) ENSXETG00000018363(PKMYT1) ENSMUSG00000031016(Wee1) "ENSG00000166483(WEE1),ENSG00000214102(WEE2)" " embryonic stage | stage 14 , embryonic stage | stage 14-17 , embryonic stage | stage 6 , embryonic stage | stage 7 , larval stage | first instar , embryonic stage | , embryonic/larval midgut

, embryonic/larval hindgut

, embryonic central nervous system

, pole cell

, mesoderm anlage

, larval brain

, organism | ubiquitous

" "female sterile,recessive,wild-type,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,visible,mitotic cell cycle defective,chemical sensitive,male fertile,non-rescuable maternal effect,viable" "nucleus | embryonic cycle 12,ommatidium,wing margin,chaeta & adult thorax | dorsalap-md544,wing,scutellum,chaeta & adult thorax | dorsalpnr-MD237,adult thorax,interommatidial bristle,mitotic cell cycleunspecified,anaphase & centrosome & cycle 13 embryo | maternal effect,anaphase & centrosome & cycle 12 embryo | maternal effect,spindle | embryonic cycle 13 | maternal effect,spindle | embryonic cycle 12 | maternal effect,microtubule organizing center | embryonic cycle 13 | maternal effect,microtubule organizing center | embryonic cycle 12 | maternal effect,interphase & centrosome & cycle 12 embryo | maternal effect,metaphase & centrosome & cycle 12 embryo | maternal effect,nucleus | ectopic | embryonic stage 4 | maternal effect,mitotic interphase | maternal effect,mitotic anaphase | embryonic cycle 12 | maternal effect,mitotic telophase | embryonic cycle 12 | maternal effect,aster | embryonic cycle 12 | maternal effect,aster | embryonic cycle 13 | maternal effect,anaphase & condensed nuclear chromosome & cycle 13 embryo | maternal effect,mitotic cell cycle,nucleus | embryonic cycle 11" FBgn0011278 lbe ladybird early http://flybase.net/reports/FBgn0011278.html FBgn0010394 protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0045664=regulation of neuron differentiation, 0007520=myoblast fusion, 0007483=genital disc morphogenesis, 0007517=muscle organ development, 0007417=central nervous system development, 0051450=myoblast proliferation, 0048813=dendrite morphogenesis, 0007507=heart development, 0048666=neuron development, 0007519=skeletal muscle tissue development, 0016477=cell migration, 0007501=mesodermal cell fate specification, 0042659=regulation of cell fate specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 1901739=regulation of myoblast fusion, 0006355=regulation of transcription, DNA-templated, 0008544=epidermis development, 0007480=imaginal disc-derived leg morphogenesis" 0005634=nucleus "Lb, Ladybird early, Hox11-D125, lady-bird-early, NK?, ladybird, Ladybird, Lbe, CG6545, lb" "IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif, IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG6545 16-Dec-15 2015_12 WBGene00003377(mls-2) "ENSXETG00000027771(HMX2),ENSXETG00000015419()" ENSMUSG00000034968(Lbx2) " embryonic stage | late , embryonic stage | stage 10-11 , embryonic stage | stage 13 , embryonic stage | stage 10-13 , embryonic stage | stage 15 , embryonic stage | stage 11 " " central nervous system | restricted

, embryonic neuroblast

, ectoderm | ventral

, dorsal ectoderm &&of abdominal segment 1--7

, embryonic peripheral nervous system | restricted

, segment border muscle

, epidermis | dorsal

, epidermis | segmentally repeated

" " embryonic stage | stage 13 , embryonic stage | stage 9-11 , embryonic stage | stage 10-13 , embryonic stage | stage 10-11 , embryonic stage | stage 15 , embryonic stage | late , embryonic stage | stage >8 " " ectoderm | ventral

, tritocerebral neuroblast | subset

, dorsal ectoderm &&of abdominal segment 1--7

, deuterocerebral neuroblast | subset

, ectoderm &&of embryonic gnathal segment

, protocerebral neuroblast | subset

, epidermis | dorsal

, embryonic peripheral nervous system | restricted

, anal pad | primordium

, central nervous system | restricted

, segment border muscle

, procephalic neurogenic region | restricted

" "locomotor behavior defective,lethal,viable" "embryonic/larval pericardial cell,embryonic cardioblast,embryonic/larval somatic muscle,adult heart,adult heart muscle,embryonic/larval dorsal vessel,precursor,dorsal denticle,EL neuron,central nervous system,exit glial cell,ectopic,glial cell,intersegmental nerve,prothoracic segmental nerve,segment border muscle,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,abdominal 1 ventral adult muscle precursor cell,abdominal 2 ventral adult muscle precursor cell,abdominal 3 ventral adult muscle precursor cell,abdominal 4 ventral adult muscle precursor cell,abdominal 5 ventral adult muscle precursor cell,abdominal 6 ventral adult muscle precursor cell,abdominal 7 ventral adult muscle precursor cell,lateral,A1-7 dorsal acute muscle 1,A1-7 dorsal oblique muscle 1,cardiac outflow muscle,aorta primordium,muscle fiber,myoblast,tarsal levator muscle,dorsal acute muscle 1,dorsal transverse muscle,ventral acute muscle 2,nucleus | supernumerarykirre.PR" FBgn0039283 danr distal antenna-related http://flybase.net/reports/FBgn0039283.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005515=protein binding" "0048749=compound eye development, 0006355=regulation of transcription, DNA-templated, 0021556=central nervous system formation, 0007379=segment specification" 0005634=nucleus "hern, Tintin, Distal antenna related, CG13651, Danr, distal antenna related, hernandez" "IPR007889=DNA binding HTH domain, Psq-type, IPR009057=Homeodomain-like" CG13651 16-Dec-15 2015_12 " pupal stage | early , larval stage | third instar " " eye-antennal disc | restricted

, antennal disc | restricted & central

, eye disc | restricted

" "visible,viable,neuroanatomy defective,lethal" "tarsal segment,third segment of antenna,basal cylinder,somatic clone,bract,ectopic,antennal segment 3 & macrochaeta | ectopicDll-md23,arista,eye,ommatidium,interommatidial bristle,ventral nerve cord,presumptive embryonic/larval nervous system,germ band,leg,distal,antenna,unguis,rostral membrane,wing,wing margin bristle" FBgn0034180 Ehbp1 Eps15 homology domain containing protein-binding protein 1 http://flybase.net/reports/FBgn0034180.html protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding" "0045035=sensory organ precursor cell division, 0045747=positive regulation of Notch signaling pathway" "0031941=filamentous actin, 0005938=cell cortex" "CG15609, dEHBP-1, dEHBP1, EHBP1, 2R11" "IPR019448=EEIG1/EHBP1 N-terminal domain, IPR001715=Calponin homology domain, IPR022735=Domain of unknown function DUF3585" CG15609 16-Dec-15 2015_12 ENSDARG00000057353 WBGene00009098(ehbp-1) ENSXETG00000013029(EHBP1) "ENSMUSG00000042302(Ehbp1),ENSMUSG00000024937(Ehbp1l1)" "ENSG00000115504(EHBP1),ENSG00000173442(EHBP1L1)" "visible,body color defective,partially lethal - majority die,some die during pupal stage,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,recessive,lethal" "mesothoracic tergum,chaeta,somatic clone" FBgn0025615 Torsin Torsin http://flybase.net/reports/FBgn0025615.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" "0048085=adult chitin-containing cuticle pigmentation, 0042053=regulation of dopamine metabolic process, 0051085=chaperone mediated protein folding requiring cofactor, 0043104=positive regulation of GTP cyclohydrolase I activity, 0071426=ribonucleoprotein complex export from nucleus, 0006457=protein folding, 0040011=locomotion" "0005783=endoplasmic reticulum, 0005635=nuclear envelope, 0005788=endoplasmic reticulum lumen" "torsin, DmTorp4a, dtor, EG:84H4.1, Torp4a, torp4a, TORP4A, CG3024, dtorsin, unnamed" "IPR017378=Torsin 1/2, IPR010448=Torsin, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR030553=Torsin-like protein" CG3024 16-Dec-15 2015_12 "ENSDARG00000055856(zgc:194342),ENSDARG00000036089,ENSDARG00000026895(zgc:77727),ENSDARG00000038889,ENSDARG00000025612(tor2a)" "WBGene00003870(ooc-5),WBGene00006598(tor-2),WBGene00006597(tor-1)" "ENSXETG00000023595(TGas090b21.1),ENSXETG00000012843(TEgg003a03.1),ENSXETG00000005251(TGas135g09.1)" "ENSMUSG00000026848(Tor1b),ENSMUSG00000026849(Tor1a),ENSMUSG00000009563(Tor2a),ENSMUSG00000060519(Tor3a)" "ENSG00000136827(TOR1A),ENSG00000136816(TOR1B),ENSG00000160404(TOR2A),ENSG00000186283(TOR3A)" "partially lethal - majority die,male sterile,body color defective,locomotor behavior defective,neuroanatomy defective,viable" "chaeta,dopaminergic neuron,NMJ bouton,NMJ bouton | third instar larval stage" FBgn0260066 2L3642 http://flybase.net/reports/FBgn0260066.html gene 16-Dec-15 2015_12 "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0002633 E(spl)m7-HLH "Enhancer of split m7, helix-loop-helix" http://flybase.net/reports/FBgn0002633.html "FBgn0020009, FBgn0020922" protein_coding_gene "0008134=transcription factor binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity" "2001020=regulation of response to DNA damage stimulus, 0048666=neuron development, 0048813=dendrite morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0031987=locomotion involved in locomotory behavior, 0001964=startle response, 0048854=brain morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development" 0005634=nucleus "E(SPL)m7, Enhancer of split m7, E(spl) m7, bHLHb35, HLHm7, M7, m7, E(spl)-M7, E(spl)M7, E(spl) region transcript 7, E(spl)m7, HlHm7, En(spl)m7, HLH-m7, ESPL, E(spl)-m7, E(spl) region transcript m7, CG8361" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG8361 16-Dec-15 2015_12 "ENSDARG00000069675(her8.2),ENSDARG00000016363(her8a)" " embryonic stage | stage 11-14 , embryonic stage | stage 5 , embryonic stage | 6-10 hr , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 7-11 , embryonic stage | stage 11-12 " " stomatogastric nervous system | primordium

, vitellophage

, supraesophageal ganglion

, epidermis | restricted

, ectoderm

, posterior midgut proper primordium

, mesoderm

, organism | striped

, optic lobe | primordium

" "visible,viable,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective" "chaeta,mesothoracic tergum,macrochaeta,microchaeta,adult thorax,ectopic,scutum & macrochaetah-1J3,wing & macrochaetaptc-559.1,scutum & macrochaetaptc-559.1,wing,scutum,campaniform sensillum of anterior crossvein,leg & macrochaeta30A,wing & macrochaeta69B,wing vein,dorsal mesothoracic disc & sensory mother cell455.2,sensory mother cell,wing & sensory mother cell455.2,eye,interommatidial bristle,scutellar bristle,adult mesothoracic segment,scutellum & macrochaetah-1J3,wing vein L2,wing vein L4,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,mesothoracic tergum & macrochaeta-C253,anterior wing margin,intersegmental nerve" FBgn0004510 Ets97D Ets at 97D http://flybase.net/reports/FBgn0004510.html FBgn0003727 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0009267=cellular response to starvation, 0006541=glutamine metabolic process, 0010821=regulation of mitochondrion organization, 0006355=regulation of transcription, DNA-templated, 0045451=pole plasm oskar mRNA localization, 0007005=mitochondrion organization" 0005634=nucleus "DELG, tne, tny, d-elg, tiny, Ets, elg, Ets like gene, tiny eggs, Elg, delg, Delg, D-elg, D-Elg, CG6338" "IPR013761=Sterile alpha motif/pointed domain, IPR003118=Pointed domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR024668=GA-binding protein alpha subunit, N-terminal, IPR000418=Ets domain, IPR016312=Transcription factor, GA-binding, alpha subunit" CG6338 16-Dec-15 2015_12 ENSDARG00000069289(gabpa) ENSXETG00000013611(GABPA) ENSMUSG00000008976(Gabpa) ENSG00000154727(GABPA) embryonic stage "

ubiquitous , pole cell

" "wild-type,female sterile,lethal,recessive,developmental rate defective,viable,visible,partially lethal - majority die,some die during pupal stage" "chorion,dorsal appendage,egg,nurse cell & nuclear chromosome,follicle cell,fat body,mitochondrion,mitochondrial chromosome,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,egg chamber,germline clone,border follicle cell,trichogen cell" DRSC27682 K -0.590114826 0.114597255 -0.022913361 0.106784789 0.432117482 -1.844911779 FBgn0002336 l(3)87Be lethal (3) 87Be http://flybase.net/reports/FBgn0002336.html gene "unnamed, 0545/01, 0643/07, l(3)ck17, ck17" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069337 UY2506 UY2506 http://flybase.net/reports/FBgn0069337.html gene unnamed 16-Dec-15 2015_12 neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body alpha-lobe,mushroom body beta-lobe" FBgn0053500 CG33500 http://flybase.net/reports/FBgn0053500.html protein_coding_gene "inverted repeat 1, unnamed" CG33500 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC09115 K 1.714254629 1.483153396 FBgn0020914 Outspan Outspan http://flybase.net/reports/FBgn0020914.html gene 16-Dec-15 2015_12 visible wing FBgn0061496 l(2)45Aq lethal (2) 45Aq http://flybase.net/reports/FBgn0061496.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0263894 D40 http://flybase.net/reports/FBgn0263894.html gene 16-Dec-15 2015_12 "cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0002981 Oce Ocellarless http://flybase.net/reports/FBgn0002981.html gene 16-Dec-15 2015_12 "visible,recessive,viable,fertile,dominant" "ocellar bristle,postvertical bristle,macrochaeta,scutellar bristle,wing,ocellus,head & macrochaeta,wing vein L5,posterior crossvein" FBgn0010015 CanA1 Calcineurin A1 http://flybase.net/reports/FBgn0010015.html "FBgn0004466, FBgn0005780" protein_coding_gene "0016787=hydrolase activity, 0004722=protein serine/threonine phosphatase activity, 0004723=calcium-dependent protein serine/threonine phosphatase activity" "0006470=protein dephosphorylation, 0007269=neurotransmitter secretion, 0030431=sleep, 0072375=medium-term memory, 0045088=regulation of innate immune response, 0071731=response to nitric oxide, 0016192=vesicle-mediated transport" "0008021=synaptic vesicle, 0005955=calcineurin complex" "D14, Protein phosphatase D14, calcineurin, CnnA21EF, unnamed, Calcineurin, PpD14, Calcineurin A, DmCanA1-100B, canA, protein phosphatase from PCR fragment D14, PP2B, Can, CnA, CNA1, Cana1, pMY4, CG1455, CAN A1/PP2B, canA1, PP2B 21EF" "IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase" CG1455 16-Dec-15 2015_12 "YML057W(CMP2),YLR433C(CNA1)" WBGene00006527(tax-6) "sleep defective,locomotor behavior defective,partially lethal - majority die,some die during pupal stage,visible,memory defective,hypoactive" "trichogen cell,mesothoracic tergum" FBgn0026418 Hsc70Cb Hsc70Cb http://flybase.net/reports/FBgn0026418.html "FBgn0010707, FBgn0010924, FBgn0013562, FBgn0026569, FBgn0027982, FBgn0028258, FBgn0028259, FBgn0062110" protein_coding_gene 0051087=chaperone binding 0006457=protein folding "0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus" "anon-WO0118547.302, l(3)S134802, 1342/17, HSC70, Hsc70, l(3)S134217, 1348/02, l(3)70Ca, l(3)07621, HSP110, hsc70cb, l(3)70Cb, BEST:LD32772, LD32772, 1485/13, l(3)148513, l(3)134217, HSC70cb, l(3)S148513, 0318/20, l(3)00082, CG6603, HSP110-1, 0041/12, HSC-70, hsc70Cb, dHsp110" "IPR029048=Heat shock protein 70kD, C-terminal domain, IPR018181=Heat shock protein 70, conserved site, IPR029047=Heat shock protein 70kD, peptide-binding domain, IPR013126=Heat shock protein 70 family" CG6603 16-Dec-15 2015_12 "ENSDARG00000018989(hspa4),ENSDARG00000053544(wu:fc07b10),ENSDARG00000019874(LOC557824),ENSDARG00000004754(hspa4l)" "YPL106C(SSE1),YBR169C(SSE2)" WBGene00016250(C30C11.4) "ENSXETG00000027138(hsp4a),ENSXETG00000019175(hsph1)" "ENSMUSG00000025757(Hspa4l),ENSMUSG00000020361(Hspa4),ENSMUSG00000029657(Hsph1)" "ENSG00000164070(HSPA4L),ENSG00000170606(HSPA4),ENSG00000120694(HSPH1)" larval stage | third instar " embryonic/larval proventriculus

, larval brain

, embryonic/larval salivary gland

, embryonic/larval midgut

, embryonic/larval hindgut

, imaginal disc

, Malpighian tubule

, gastric caecum

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "arista,trichogen cell,mesothoracic tergum" DRSC26538 K -0.366952366 -0.421282707 -0.365583218 0.31177533 1.832017136 0.193143432 FBgn0003744 trc tricornered http://flybase.net/reports/FBgn0003744.html "FBgn0014866, FBgn0028111" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0005515=protein binding" "0048800=antennal morphogenesis, 0035556=intracellular signal transduction, 0035317=imaginal disc-derived wing hair organization, 0006468=protein phosphorylation, 0007476=imaginal disc-derived wing morphogenesis, 0007165=signal transduction, 0070593=dendrite self-avoidance, 0048814=regulation of dendrite morphogenesis, 0040018=positive regulation of multicellular organism growth, 0048813=dendrite morphogenesis, 0022416=chaeta development" "0005634=nucleus, 0005737=cytoplasm, 0030424=axon, 0044297=cell body, 0005938=cell cortex, 0030425=dendrite, 0070451=cell hair, 0071944=cell periphery" "tricorner, Ndr, RE-D, NDR, l(3)76BDa, l(3)S066917, Nuclear Dbf2-related protein kinase, Trc, CG8637, 0669/17, dmTRC, Tricornered" "IPR017892=Protein kinase, C-terminal, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG8637 16-Dec-15 2015_12 "ENSDARG00000019973(zgc:55572),ENSDARG00000018516(LOC567906),ENSDARG00000045482(stk38l)" YNL161W(CBK1) WBGene00004727(sax-1) "ENSXETG00000016625(STK38),ENSXETG00000020514(stk38l)" "ENSMUSG00000024006(Stk38),ENSMUSG00000001630(Stk38l)" "ENSG00000211455(STK38L),ENSG00000112079(STK38)" "visible,somatic clone,lethal,recessive,cell shape defective,lethal - all die before end of embryonic stage,some die during embryonic stage,developmental rate defective,viable,planar polarity defective,neuroanatomy defective,female fertile,lethal - all die before end of pupal stage,some die during pupal stage" "multidendritic neuron & dendrite | supernumerary477,multidendritic neuron & dendrite477,wing hair,somatic clone,supernumerary,arista,cell autonomous,denticle,antenna,arista lateral,wing,trichome,macrochaeta,trichogen cell,adult abdominal sensillum,dendritic arborizing neuron,dendrite,denticle belt,multidendritic neuron & dendrite | supernumerary,multidendritic neuron & dendrite,dendrite | cell autonomous | somatic clone | supernumerary,multidendritic neuron & dendrite | somatic clone,egg,dorsal multidendritic neuron ddaC,follicle cell,actin filament | somatic clone,egg chamber" FBgn0010288 Uch Ubiquitin carboxy-terminal hydrolase http://flybase.net/reports/FBgn0010288.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0006511=ubiquitin-dependent protein catabolic process, 0016579=protein deubiquitination" 0005875=microtubule associated complex "UCH-D19, CG4265, ubiquitin C-terminal hydrolase, UBL, dUch, ubiquitin carboxyterminal hydrolase, uch, uch-D, Uch-D, ubiquitin carboxyl terminal hydrolase, UCH, UCH-D, P35122" "IPR001578=Peptidase C12, ubiquitin carboxyl-terminal hydrolase" CG4265 16-Dec-15 2015_12 ENSDARG00000030177(uchl3) YJR099W(YUH1) "WBGene00006723(ubh-3),WBGene00006722(ubh-2),WBGene00006721(ubh-1)" ENSXETG00000004711(uchl3) "ENSMUSG00000022111(Uchl3),ENSMUSG00000035337(Uchl4),ENSMUSG00000029223(Uchl1)" "ENSG00000118939(UCHL3),ENSG00000154277(UCHL1)" " adult stage && oogenesis stage , spermatogenesis && adult stage " " nurse cell

, oocyte

, spermatocyte

" "viable,fertile" FBgn0029003 mab-21 mab-21 http://flybase.net/reports/FBgn0029003.html FBgn0029832 protein_coding_gene "mab-2, CG4746" "IPR024810=Mab-21 domain, IPR020950=Protein male abnormal 21-related" CG4746 16-Dec-15 2015_12 "ENSDARG00000055089(mab21l1),ENSDARG00000015266(mab21l2)" WBGene00003112(mab-21) ENSXETG00000017124(MAB21L1) "ENSMUSG00000056947(Mab21l1),ENSMUSG00000057777(Mab21l2)" "ENSG00000181541(MAB21L2),ENSG00000180660(MAB21L1)" "viable,fertile" FBgn0041205 key kenny http://flybase.net/reports/FBgn0041205.html FBgn0035066 protein_coding_gene 0005515=protein binding "0051607=defense response to virus, 2000647=negative regulation of stem cell proliferation, 0006955=immune response, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0002230=positive regulation of defense response to virus by host, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0019730=antimicrobial humoral response, 0030163=protein catabolic process, 0008063=Toll signaling pathway" "0005634=nucleus, 0005737=cytoplasm, 0008385=IkappaB kinase complex" "Dmikkgamma, KEY, IKKg, IKK, IKKG, DmIKKgamma, dmIKKgamma, dIKK, IKKgamma, dIKK-gamma, DmIKK-gamma, Kenny, IKK[[gamma]], kenny, Kenney, CG16910, Key, IKK-gamma" "IPR015880=Zinc finger, C2H2-like" CG16910 16-Dec-15 2015_12 "ENSDARG00000002663(optn),ENSDARG00000017037(ikbkg)" ENSXETG00000009111(OPTN) "ENSMUSG00000026672(Optn),ENSMUSG00000004221(Ikbkg)" "viable,fertile,immune response defective,recessive,oxidative stress response defective" intestinal stem cell FBgn0025161 l(2)GA1019 lethal (2) GA1019 http://flybase.net/reports/FBgn0025161.html gene GA1019 16-Dec-15 2015_12 "lethal,recessive,cytokinesis defective" ganglion mother cell GMC4-2a FBgn0002868 MtnA Metallothionein A http://flybase.net/reports/FBgn0002868.html "FBgn0045904, FBgn0045909, FBgn0045911, FBgn0064964" protein_coding_gene 0046872=metal ion binding "0055065=metal ion homeostasis, 0010038=response to metal ion" "anon-WO0153538.42, DrosMtn, metallothionein A, mtnA, CG9470, MTN, Mtn, anon-WO0153538.44, metallothionein, anon-WO0153538.49, BcDNA:GH18460, metallothionein N" "IPR000966=Metallothionein, family 5, Diptera" CG9470 16-Dec-15 2015_12 "chemical sensitive,viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum,trichogen cell" FBgn0039747 AdoR Adenosine receptor http://flybase.net/reports/FBgn0039747.html "FBgn0046615, FBgn0046617" protein_coding_gene 0001609=G-protein coupled adenosine receptor activity "0022008=neurogenesis, 0007268=synaptic transmission, 0090281=negative regulation of calcium ion import, 0001973=adenosine receptor signaling pathway, 0006109=regulation of carbohydrate metabolic process, 0007186=G-protein coupled receptor signaling pathway, 0090279=regulation of calcium ion import, 0008306=associative learning, 0030819=positive regulation of cAMP biosynthetic process" 0016021=integral component of membrane "adoR, anon-WO0170980.110, dADOR, CG9753, adenosine receptor, anon-WO0170980.109, DmAdoR, dAdoR" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG9753 16-Dec-15 2015_12 "visible,melanotic mass phenotype,lethal,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,viable,learning defective,recessive,neurophysiology defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,melanotic mass,scutellum,scutellar bristle,adult external abdomen,embryonic/larval neuromuscular junction,motor neuron,synapse,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0021796 Tor Target of rapamycin http://flybase.net/reports/FBgn0021796.html FBgn0032466 protein_coding_gene "0043621=protein self-association, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0008144=drug binding" "0048813=dendrite morphogenesis, 2000331=regulation of terminal button organization, 0035264=multicellular organism growth, 0016242=negative regulation of macroautophagy, 0040018=positive regulation of multicellular organism growth, 2001023=regulation of response to drug, 0007525=somatic muscle development, 0007411=axon guidance, 0007584=response to nutrient, 0001934=positive regulation of protein phosphorylation, 2000377=regulation of reactive oxygen species metabolic process, 0045793=positive regulation of cell size, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 0009594=detection of nutrient, 0048142=germarium-derived cystoblast division, 0042331=phototaxis, 0051124=synaptic growth at neuromuscular junction, 0040007=growth, 0007520=myoblast fusion, 0001558=regulation of cell growth, 0030307=positive regulation of cell growth, 0032456=endocytic recycling, 0016310=phosphorylation, 0008406=gonad development, 0006974=cellular response to DNA damage stimulus, 0090070=positive regulation of ribosome biogenesis, 0046622=positive regulation of organ growth" "0031931=TORC1 complex, 0031932=TORC2 complex" "dTOR, Target-of-rapamycin, TOR, Target-of-Rapamycin, tor, Tor|TOR, CT24817, target of rapamycin kinase, CT24745, CG5092, Target Of Rapamycin, dtor, Target of Rapamycin, l(2)k17004, FRAP/TOR, unnamed, 5092, CT16317, DmTOR, mTOR, target-of-rapamycin, TORC1, target of rapamycin, dTor" "IPR014009=PIK-related kinase, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR003152=FATC domain, IPR011009=Protein kinase-like domain, IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR009076=Rapamycin-binding domain, IPR019734=Tetratricopeptide repeat, IPR016024=Armadillo-type fold, IPR024585=Domain of unknown function DUF3385, target of rapamycin protein, IPR011989=Armadillo-like helical, IPR003151=PIK-related kinase, FAT, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain" CG5092 16-Dec-15 2015_12 ENSDARG00000053196(mtor) "YJR066W(TOR1),YKL203C(TOR2)" WBGene00002583(let-363) ENSMUSG00000028991(Mtor) ENSG00000198793(MTOR) "neuroanatomy defective,somatic clone,small body,lethal,recessive,body size defective,decreased cell size,gravitaxis defective,wild-type,mitotic cell cycle defective,developmental rate defective,cell size defective,decreased cell number,lethal - all die before end of larval stage,some die during larval stage,sterile,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,chemical sensitive,dominant,lethal - all die before end of second instar larval stage,some die during second instar larval stage,long lived,visible,size defective,increased cell size,some die during third instar larval stage" "axon | somatic clone,dendrite | somatic clone,anterior fascicle & synapse,intersegmental nerve,larva,larval salivary gland & nucleus,fat body,vesicle,nucleus,intestinal stem cell,chemical conditional,salivary gland imaginal ring,cell cycle,dorsal mesothoracic disc & nucleolus,embryonic/larval fat body,somatic clone,dendritic arborizing neuron,eye disc,embryonic/larval salivary gland,ovary,testis,head,segment border muscle,embryonic/larval somatic muscle,embryonic myoblast,embryonic/larval neuroblast,hemocyte | larval stage,wing,posterior,lysosomeLsp2.PH,autophagic vacuoleLsp2.PH,autophagic vacuoleGMR.PU,eye,mitotic cell cycle | somatic clone,eye-antennal disc primordium" DRSC02811 I -2.259015858 2.217170773 0.006915707 0.300893799 -0.136363955 0.08512951 FBgn0003447 sn singed http://flybase.net/reports/FBgn0003447.html FBgn0040925 protein_coding_gene "0051015=actin filament binding, 0003779=actin binding, 0030674=protein binding, bridging" "0009913=epidermal cell differentiation, 0008407=chaeta morphogenesis, 0048812=neuron projection morphogenesis, 0030034=microvillar actin bundle assembly, 0048800=antennal morphogenesis, 0035017=cuticle pattern formation, 0035099=hemocyte migration, 0030036=actin cytoskeleton organization, 0007163=establishment or maintenance of cell polarity, 0048477=oogenesis, 0035317=imaginal disc-derived wing hair organization, 0046847=filopodium assembly, 0042060=wound healing, 0051017=actin filament bundle assembly, 0016358=dendrite development, 0007015=actin filament organization" "0043005=neuron projection, 0015629=actin cytoskeleton, 0005737=cytoplasm, 0031941=filamentous actin, 0043025=neuronal cell body" "Singed, fs(1)K1421, Fascin, CG32858, fs(1)A1057, SN, fs(1)K473, fs(1)K418, fascin, fs(1)K743, fs(1)M45, CG1536, CG15331, Sn" "IPR008999=Actin cross-linking, IPR022768=Fascin domain, IPR010431=Fascin, IPR024703=Fascin, metazoans" CG32858 16-Dec-15 2015_12 "ENSDARG00000059680(fscn1),ENSDARG00000037747(LOC100334097),ENSDARG00000006460,ENSDARG00000059574(LOC798075)" "ENSXETG00000015030(FSCN2),ENSXETG00000007501(fscn1)" "ENSMUSG00000029581(Fscn1),ENSMUSG00000025380(Fscn2)" "ENSG00000075618(FSCN1),ENSG00000186765(FSCN2)" " pupal stage , embryonic stage | early , adult stage && oogenesis stage | mid-late , adult stage , oogenesis stage | mid-late " ovary

" pupal stage , oogenesis stage | stage S9 && adult stage | female , oogenesis stage | stage S10 && adult stage | female " " tormogen cell

, border follicle cell

, macrochaeta

, oocyte

, socket

" "female sterile,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,viable,fertile,visible,partially,sterile,neuroanatomy defective,female fertile,reduced,male fertile,cell polarity defective,cell migration defective,female" "macrochaeta,microchaeta,dorsal appendage,egg,maternal effect,orbital bristle,chaeta,lateral multidendritic neuron ldaB,dorsal multidendritic neuron ddaC,denticle belt,actin filament & egg chamber,macrochaeta & actin filament,nurse cell ring canal,plasmatocyte,neuron,actin filament & neuron,nurse cell,egg chamber,oocyte,nurse cell & nucleus,macrophage,arista,microchaeta & actin filament,denticle,wing hair" FBgn0000535 eag ether a go-go http://flybase.net/reports/FBgn0000535.html protein_coding_gene "0022843=voltage-gated cation channel activity, 0000155=phosphorelay sensor kinase activity, 0005249=voltage-gated potassium channel activity" "0007612=learning, 0007608=sensory perception of smell, 0007619=courtship behavior, 0048150=behavioral response to ether, 0051259=protein oligomerization, 0008016=regulation of heart contraction, 0007629=flight behavior, 0042066=perineurial glial growth, 0006813=potassium ion transport, 0071805=potassium ion transmembrane transport, 0042391=regulation of membrane potential, 0007611=learning or memory, 0000160=phosphorelay signal transduction system" "0005886=plasma membrane, 0008076=voltage-gated potassium channel complex, 0005887=integral component of plasma membrane" "EAG, CG10952, ether-a-gogo, ether-a-go-go, Eag, CIKE, Ether-a-go-go, ether-a go-go" "IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like, IPR030171=Potassium voltage-gated channel subfamily H member 5, IPR000700=PAS-associated, C-terminal, IPR003938=Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR003949=Potassium channel, voltage-dependent, EAG, IPR014710=RmlC-like jelly roll fold, IPR001610=PAC motif, IPR005821=Ion transport domain, IPR000014=PAS domain, IPR030170=Potassium voltage-gated channel subfamily H member 1" CG10952 16-Dec-15 2015_12 "ENSDARG00000024167(kcnh1),ENSDARG00000023236(LOC568733),ENSDARG00000043220(kcnh5a),ENSDARG00000069117(LOC100331767)" WBGene00001171(egl-2) ENSXETG00000000225(KCNH1) "ENSMUSG00000034402(Kcnh5),ENSMUSG00000058248(Kcnh1)" "ENSG00000140015(KCNH5),ENSG00000143473(KCNH1)" adult stage adult head

"neurophysiology defective,behavior defective,learning defective,smell perception defective,memory defective,taste perception defective,chemical sensitive,recessive,hyperactive,heat sensitive,viable,courtship behavior defective,song defective" "adult brain,neuromuscular junction,synapse,leg" FBgn0053276 CG33276 http://flybase.net/reports/FBgn0053276.html FBgn0043540 protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0034227=tRNA thio-modification" "0005576=extracellular region, 0005737=cytoplasm" "anon-AE003558.1, unnamed" "IPR015221=Ubiquitin-related modifier 1, IPR012675=Beta-grasp domain, IPR016155=Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp" CG33276 16-Dec-15 2015_12 YIL008W(URM1) ENSMUSG00000069020(Urm1) ENSG00000167118(URM1) viable FBgn0010329 Tbh Tyramine ë_ hydroxylase http://flybase.net/reports/FBgn0010329.html FBgn0012186 protein_coding_gene "0004500=dopamine beta-monooxygenase activity, 0016715=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, 0005507=copper ion binding" "0048149=behavioral response to ethanol, 0055114=oxidation-reduction process, 0006589=octopamine biosynthetic process, 0007613=memory, 0007612=learning, 0050795=regulation of behavior, 0008345=larval locomotory behavior, 0007629=flight behavior, 0043059=regulation of forward locomotion, 0002118=aggressive behavior, 0048047=mating behavior, sex discrimination, 0030728=ovulation, 0040011=locomotion, 0071927=octopamine signaling pathway, 0002121=inter-male aggressive behavior, 0008049=male courtship behavior" "tyramine beta-hydroxylase, TbetaM, tyramine-beta-hydroxylase, TBetah, tyroside beta-hydroxylase, DBH, Tbetah, T beta h, Dopamine beta hydroxylase, TBh, tyramine beta hydroxylase, TbH, tyramine beta-monooxygenase, TBH, tbh, tyrosine beta hydroxylase, TBetaH, CG1543, Dbh, Tyramine beta hydroxylase, Tyramine Beta Hydroxylase, TbetaH, Tyramine beta-hydroxylase, tbetah" "IPR014784=Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR000945=Dopamine beta-hydroxylase-related, IPR008977=PHM/PNGase F domain, IPR005018=DOMON domain, IPR024548=Copper type II ascorbate-dependent monooxygenase, C-terminal, IPR028460=Tyramine beta-hydroxylase/Dopamine beta-hydroxylase, IPR020611=Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site, IPR000323=Copper type II, ascorbate-dependent monooxygenase, N-terminal" CG1543 16-Dec-15 2015_12 ENSDARG00000069446(dbh) WBGene00006541(tbh-1) ENSXETG00000023110(DBH) ENSMUSG00000000889(Dbh) ENSG00000123454(DBH) adult stage | female " ovary | restricted & vicinity of

, ventral nervous system | restricted & ventral & medial

, oviduct | vicinity of

" "viable,male fertile,female sterile,behavior defective,heat sensitive,fertile,memory defective,locomotor behavior defective,locomotor rhythm defective,neurophysiology defective,male,recessive,mating behavior defective,female limited,courtship behavior defective,neuroanatomy defective,female,flight defective,learning defective,conditional,starvation stress response defective,chemosensitive behavior defective" "larva,gustatory receptor neuron,multidendritic neuron,type I bouton,type II bouton,embryonic/larval neuromuscular junction" FBgn0001987 Gli Gliotactin http://flybase.net/reports/FBgn0001987.html protein_coding_gene "0042043=neurexin family protein binding, 0052689=carboxylic ester hydrolase activity, 0004872=receptor activity" "0008065=establishment of blood-nerve barrier, 0061343=cell adhesion involved in heart morphogenesis, 0019991=septate junction assembly, 0007416=synapse assembly, 0048515=spermatid differentiation, 0007298=border follicle cell migration, 0035151=regulation of tube size, open tracheal system, 0008039=synaptic target recognition, 0035321=maintenance of imaginal disc-derived wing hair orientation, 0016321=female meiosis chromosome segregation" "0005887=integral component of plasma membrane, 0061689=tricellular tight junction, 0009986=cell surface, 0005886=plasma membrane, 0005918=septate junction, 0045202=synapse" "BG:DS09217.3, CG3903, n(2)k09033, gliotactin, l(2)35Dg, l(2)br45, gli" "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR002018=Carboxylesterase, type B" CG3903 16-Dec-15 2015_12 WBGene00018878(glit-1) " embryonic stage , embryonic stage | stage 12 " " exit glial cell

, peripheral glial cell

, epidermis

, midline glial cell

" " embryonic stage , larval stage , embryonic stage | stage >=13 , embryonic stage | stage 12 , embryonic stage | stage 13-14 " " segmental nerve

, peripheral nervous system

, peripheral glial cell

, ventral thoracic disc

, epidermis

, eye-antennal disc

, thoracico-abdominal ganglion | medial

, exit glial cell

, embryonic/larval trachea

, midline glial cell

, embryonic/larval hindgut

, intersegmental nerve

" "lethal,increased cell number,increased cell death,viable,fertile,visible,neuroanatomy defective,meiotic cell cycle defective,dominant,recessive,cell polarity defective,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,cell lethalcell lethal,somatic clone" "border follicle cell,somatic clone,wing disc,embryonic/larval salivary gland,macrochaeta,tormogen cell,scutellar bristle,dorsocentral bristle,intersegmental nerve,anterior fascicle & synapse,dorsal trunk primordium,embryonic salivary gland & epithelial cell,septate junction,wing hair,embryonic peripheral glial cell 4,intermediate peripheral glial cell of ISN,embryonic peripheral glial cell 10,peripheral glial cell 4 of SNc,wing,distal,pleated septate junction,epithelial cell,embryonic/first instar larval cuticle,trichogen cell" FBgn0003575 su(sable) suppressor of sable http://flybase.net/reports/FBgn0003575.html protein_coding_gene "0003729=mRNA binding, 0046872=metal ion binding, 0003723=RNA binding" "0045892=negative regulation of transcription, DNA-templated, 0071027=nuclear RNA surveillance" "0005700=polytene chromosome, 0005654=nucleoplasm, 0035327=transcriptionally active chromatin, 0005634=nucleus" "su[2]-s, suppressor-of-sable, CG6222, su-v, su(s), Suppressor of sable, EG:115C2.3, su-s" "IPR000571=Zinc finger, CCCH-type" CG6222 16-Dec-15 2015_12 "ENSMUSG00000059273(Zc3h4),ENSMUSG00000042851(Zc3h6)" "ENSG00000130749(ZC3H4),ENSG00000188177(ZC3H6)" " adult stage , embryonic stage -- adult stage , embryonic stage " " larval stage | third instar , embryonic stage " salivary gland

"viable,good,wild-type,reduced,male sterile,recessive,cold sensitive,partially lethal - majority live,lethal,male fertile,partially,partially lethal - majority die,visible,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0001234 Hsrìä Heat shock RNA ìä http://flybase.net/reports/FBgn0001234.html FBgn0051400 non_protein_coding_gene "0030162=regulation of proteolysis, 0048477=oogenesis, 0032270=positive regulation of cellular protein metabolic process, 0043065=positive regulation of apoptotic process, 0008104=protein localization, 0035063=nuclear speck organization, 0009408=response to heat, 0046330=positive regulation of JNK cascade" "0000785=chromatin, 0035062=omega speckle" "n(3)05241, l(3)93De, hsr omega, Hsr omega, CR31400, hsromega, Heat-shock response factor-omega, Hsromega-n, hsr-omega, hrsomega, Hsr93D, Heat shock RNA omicron, Heat-shock RNA omega, Heat shock RNA omega, heat-shock RNA-omega, l(3)er3, heat- shock RNA omega, hsrw, heat-shock RNA ohgr, 93D locus, l(3)05241, unnamed, er3, HSRomega, Hsromega, Hsr-omega, heat shock RNA omega" CR31400 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage -- adult stage , adult stage | male , embryonic stage | stage >=5 , oogenesis stage , larval stage--adult stage , spermatogenesis " " embryonic/larval proventriculus

, prothoracic gland

, gastric caecum

, embryonic/larval midgut | restricted

, larval optic lobe

, embryonic/larval salivary gland

, embryonic/larval hindgut

, Malpighian tubule

, male reproductive system | restricted

, organism

, nurse cell

, ventral nerve cord

, imaginal disc

, testis | restricted

" "partially lethal - majority die,fertile,heat stress response defective,recessive,viable,male fertile,female fertile,visible,semi-fertile" "rhabdomere,ommatidium,ommatidial precursor cluster" FBgn0000167 bch branch http://flybase.net/reports/FBgn0000167.html gene 0035293=chitin-based larval cuticle pattern formation 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" denticle belt FBgn0038593 Vps39 Vacuolar protein sorting 39 http://flybase.net/reports/FBgn0038593.html protein_coding_gene "0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0009267=cellular response to starvation, 0035542=regulation of SNARE complex assembly, 0008593=regulation of Notch signaling pathway, 0048812=neuron projection morphogenesis, 0000046=autophagic vacuole fusion" 0030897=HOPS complex "CG7146, dVps39, vps39, Vps39" "IPR001180=Citron homology (CNH) domain, IPR019452=Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1, IPR017986=WD40-repeat-containing domain, IPR000547=Clathrin, heavy chain/VPS, 7-fold repeat, IPR019453=Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2" CG7146 16-Dec-15 2015_12 ENSDARG00000061508(tgfbrap1) YDL077C(VAM6) WBGene00011625(vps-39) ENSXETG00000000301(VPS39) ENSMUSG00000027291(Vps39) ENSG00000166887(VPS39) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum,embryonic/larval fat body,somatic clone,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0015544 spag spaghetti http://flybase.net/reports/FBgn0015544.html "FBgn0021904, FBgn0034984" protein_coding_gene "0030544=Hsp70 protein binding, 0051879=Hsp90 protein binding, 0051087=chaperone binding" "2000672=negative regulation of motor neuron apoptotic process, 0007446=imaginal disc growth, 0007444=imaginal disc development, 0046529=imaginal disc fusion, thorax closure, 0008283=cell proliferation, 1904059=regulation of locomotor rhythm" 0005737=cytoplasm "CG13570, l(2)k12101, Spag, Spaghetti" "IPR025986=RNA-polymerase II-associated protein 3-like, C-terminal domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat" CG13570 16-Dec-15 2015_12 ENSXETG00000014674(TNeu057e12.1) ENSMUSG00000022466(Rpap3) ENSG00000005175(RPAP3) "lethal,recessive,melanotic mass phenotype,visible,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,neuroanatomy defective,wild-type,lethal - all die during pupal stage" "imaginal disc,embryonic/larval lymph gland,melanotic mass & hemocoel,wing,trichome,secondary lobe of embryonic/larval lymph gland,tertiary lobe of embryonic/larval lymph gland,melanotic mass,synapse" FBgn0039559 Mes-4 Mes-4 http://flybase.net/reports/FBgn0039559.html protein_coding_gene "0018024=histone-lysine N-methyltransferase activity, 0008270=zinc ion binding, 0008134=transcription factor binding, 0042054=histone methyltransferase activity, 0031490=chromatin DNA binding, 0003712=transcription cofactor activity" "0018992=germ-line sex determination, 0016458=gene silencing" "0000228=nuclear chromosome, 0005721=pericentric heterochromatin, 0005700=polytene chromosome" "dMES-4, CG4976, MES-4, dMes-4" "IPR001214=SET domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR003616=Post-SET domain, IPR001841=Zinc finger, RING-type, IPR001965=Zinc finger, PHD-type, IPR000313=PWWP domain, IPR019787=Zinc finger, PHD-finger, IPR006560=AWS domain" CG4976 16-Dec-15 2015_12 "ENSDARG00000062765,ENSDARG00000026225(whsc1),ENSDARG00000060705,ENSDARG00000060016" "ENSMUSG00000021488(Nsd1),ENSMUSG00000057406(Whsc1),ENSMUSG00000054823(Whsc1l1)" "ENSG00000165671(NSD1),ENSG00000109685(WHSC1),ENSG00000147548(WHSC1L1)" viable FBgn0030159 CG9689 http://flybase.net/reports/FBgn0030159.html FBgn0062505 protein_coding_gene "BcDNA:GH05731, lincRNA.S9020" CG9689 16-Dec-15 2015_12 viable FBgn0259628 B1368 http://flybase.net/reports/FBgn0259628.html gene 16-Dec-15 2015_12 visible "submarginal cell,wing vein,posterior cell,wing,tarsal segment" FBgn0069162 mcl(3)Z1898 mcl(3)Z1898 http://flybase.net/reports/FBgn0069162.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0040765 luna luna http://flybase.net/reports/FBgn0040765.html "FBgn0033575, FBgn0053473" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding, 0003677=DNA binding" "0035185=preblastoderm mitotic cell cycle, 0006355=regulation of transcription, DNA-templated, 0000070=mitotic sister chromatid segregation" 0005634=nucleus "CG33473, lincRNA.284, Klf, LUNA, CG9087, DKLF, CG17326, KLF" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG33473 16-Dec-15 2015_12 ENSDARG00000043821(klf7l) WBGene00013970(ZK337.2) ENSXETG00000016394(KLF7) "ENSMUSG00000025959(Klf7),ENSMUSG00000000078(Klf6)" ENSG00000102554(KLF5) larval stage | third instar eye-antennal disc

"lethal - all die during embryonic stage,germline clone,mitotic cell cycle defective,maternal effect,oxidative stress response defective,visible,lethal,melanotic necrosis" "eye,ommatidium,interommatidial bristle,supernumerary,pigment cell,eye photoreceptor cell,photoreceptor cell" FBgn0038156 CG14372 http://flybase.net/reports/FBgn0038156.html FBgn0082833 protein_coding_gene "14372, CT34011, BP1073, unnamed" "IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013162=CD80-like, immunoglobulin C2-set, IPR013106=Immunoglobulin V-set domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG14372 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" "viable,body color defective" mesothoracic tergum FBgn0026597 Axn Axin http://flybase.net/reports/FBgn0026597.html FBgn0028152 protein_coding_gene "0005096=GTPase activator activity, 0008013=beta-catenin binding, 0019901=protein kinase binding" "0010941=regulation of cell death, 0007507=heart development, 0016055=Wnt signaling pathway, 0048477=oogenesis, 0038032=termination of G-protein coupled receptor signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0042594=response to starvation, 0006909=phagocytosis, 0007455=eye-antennal disc morphogenesis, 0035019=somatic stem cell maintenance, 0030178=negative regulation of Wnt signaling pathway, 0007447=imaginal disc pattern formation" "0005634=nucleus, 0005737=cytoplasm, 0005886=plasma membrane" "D-Axin, l(3)S044230, Axin, D-axin, APC, din, GSK3beta, Daxin, daxin, CG7926, axin, 0442/30, d-Axin, dAXIN, dAxin, d-axin, Dm Axin, axn, DAxin, Axn" "IPR029071=Ubiquitin-related domain, IPR001158=DIX domain, IPR024066=RGS, subdomain 1, IPR014936=Axin beta-catenin binding, IPR016137=RGS domain" CG7926 16-Dec-15 2015_12 "ENSDARG00000026534(axin1),ENSDARG00000014147(axin2)" WBGene00004202(pry-1) "ENSXETG00000013607(AXIN2),ENSXETG00000012143(AXIN1),ENSXETG00000010058(axin2)" "ENSMUSG00000024182(Axin1),ENSMUSG00000000142(Axin2)" "ENSG00000103126(AXIN1),ENSG00000168646(AXIN2)" embryonic stage -- adult stage embryonic stage "partially lethal - majority live,maternal effect,some die during embryonic stage,lethal,majority die during embryonic stage,lethal - all die before end of P-stage,lethal - all die during embryonic stage,recessive,visible,somatic clone,cell shape defective,lethal - all die before end of embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,viable,wild-type,mitotic cell cycle defective,neuroanatomy defective" "denticle row 1,maternal effect,denticle belt,embryonic/first instar larval cuticle,denticle row,ectopic,wing,somatic clone,wing margin bristle,follicle stem cell,germline cyst,follicle cell,G1 phase | somatic clone,cell autonomous,macrochaeta,leg,adult abdomen,adult abdomen & macrochaeta | somatic clone,intestinal stem cell,germline clone,wing disc,denticle,supernumerary,sternite,wing margin,embryonic/larval cuticle | embryonic stage,eye disc,eye,frons,adult cuticle,mitotic cell cycle | somatic clone,photoreceptor cell,wing & chaeta | ectopic | somatic clone,embryonic epidermis,morphogenetic furrow,ovary,mesothoracic tergum,trichome of the posterior wing margin,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval lateral trunk,tracheal tip cell,ventral thoracic disc,abdominal sternite bristle,multidendritic neuron,dorsal medial muscle,indirect flight muscle,adult heart,tracheal fusion cell" DRSC14120 IK 2.752572319 -2.201592853 -0.290373448 0.405321213 2.560180287 1.811448276 FBgn0261869 caboose caboose http://flybase.net/reports/FBgn0261869.html gene 0035177=larval foraging behavior cbs 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085005 ey::eyg ey::eyg http://flybase.net/reports/FBgn0085005.html engineered_fusion_gene 16-Dec-15 2015_12 "eye,ectopic,ventral,eye | pharate adult stage,wing disc" FBgn0031059 CG14229 http://flybase.net/reports/FBgn0031059.html FBgn0047121 protein_coding_gene BcDNA:RE31307 CG14229 16-Dec-15 2015_12 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0020887 Su(z)12 Su(z)12 http://flybase.net/reports/FBgn0020887.html "FBgn0025924, FBgn0036917" protein_coding_gene "0005515=protein binding, 0046976=histone methyltransferase activity (H3-K27 specific), 0042054=histone methyltransferase activity, 0031491=nucleosome binding" "0016571=histone methylation, 0022008=neurogenesis, 0048813=dendrite morphogenesis, 0048666=neuron development, 2001229=negative regulation of response to gamma radiation, 0008283=cell proliferation, 0007517=muscle organ development" "0035098=ESC/E(Z) complex, 0035097=histone methyltransferase complex, 0005704=polytene chromosome band, 0005634=nucleus" "Su(z)[12], SUZ12, l(3)76BDo, Suppressor-of-zeste-12, Suppressor of zeste 12, SU(Z)12, Suppressor of zeste[12], Su(Z)12, CG8013, su(z)12" "IPR015880=Zinc finger, C2H2-like, IPR019135=Polycomb protein, VEFS-Box" CG8013 16-Dec-15 2015_12 "ENSDARG00000070256(suz12a),ENSDARG00000052022(suz12b)" ENSXETG00000020055(SUZ12) ENSMUSG00000017548(Suz12) ENSG00000178691(SUZ12) "suppressor of variegation,dominant,decreased cell number,somatic clone,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,visible,lethal,homeotic,viable" "egg,germline clone,neuroblast,somatic clone,dendrite & dendritic arborising neuron | somatic clone,wing,cell non-autonomous,wing hinge,cell autonomous,embryonic abdominal segment,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic head segment,dendrite & dendritic arborising neuron,dendrite & dendritic arborising neuron125),ovary,dendrite & dorsal multidendritic neuron ddaC | somatic clone,sex comb,ectopic,mesothoracic metatarsus,antenna,leg,haltere,metathoracic metatarsus,dendrite & dendritic arborising neuron122),embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0030994 HP1D3csd Heterochromatin Protein 1D3 chromoshadow domain http://flybase.net/reports/FBgn0030994.html protein_coding_gene 0003682=chromatin binding 0051276=chromosome organization 0000785=chromatin "HP1D3csd, CG14193" IPR016197=Chromo domain-like CG14193 16-Dec-15 2015_12 "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0060523 l(3)S102303b lethal (3) S102303b http://flybase.net/reports/FBgn0060523.html gene 1023/03 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0004921 Gë_1 G protein ë_ 1 http://flybase.net/reports/FBgn0004921.html FBgn0022062 protein_coding_gene "0003924=GTPase activity, 0004871=signal transducer activity" "0007155=cell adhesion, 0007015=actin filament organization, 0045176=apical protein localization, 0022008=neurogenesis, 0007391=dorsal closure, 0007637=proboscis extension reflex, 0003015=heart process, 0035050=embryonic heart tube development, 0055059=asymmetric neuroblast division, 0008360=regulation of cell shape, 0007186=G-protein coupled receptor signaling pathway, 0061343=cell adhesion involved in heart morphogenesis" "0005834=heterotrimeric G-protein complex, 0005886=plasma membrane" "Gg1, Gbetagamma, Ggamma, Ggamma1, bro4, G protein subunit gamma1, G-protein gamma subunit 1, Ggamma-1, D-G[[gamma]]1, G protein gamma1, G protein gamma 1, dg1alpha, G[[gamma]], G[[gamma1]], G protein Gg1, CG8261, l(2)k08017" "IPR015898=G-protein gamma-like domain, IPR001770=G-protein, gamma subunit" CG8261 16-Dec-15 2015_12 "ENSDARG00000038693(gng7),ENSDARG00000003375(gng12a),ENSDARG00000070003(LOC100332296),ENSDARG00000056831(gng2),ENSDARG00000009553(gng3),ENSDARG00000052380(LOC100000320),ENSDARG00000062537(LOC100330260),ENSDARG00000042970(gng8),ENSDARG00000039830(gng5)" WBGene00001681(gpc-1) "ENSXETG00000026842(gng7),ENSXETG00000016492(gng2),ENSXETG00000024886(),ENSXETG00000025073()" "ENSMUSG00000036402(Gng12),ENSMUSG00000048240(Gng7),ENSMUSG00000043004(Gng2),ENSMUSG00000071658(Gng3),ENSMUSG00000021303(Gng4),ENSMUSG00000063594(Gng8),ENSMUSG00000068523(Gng5),ENSMUSG00000038607(Gng10),ENSMUSG00000078297(Gm3150),ENSMUSG00000032766(Gng11)" "ENSG00000172380(GNG12),ENSG00000213611,ENSG00000186469(GNG2),ENSG00000168243(GNG4),ENSG00000162188(GNG3),ENSG00000167414(GNG8),ENSG00000174021(GNG5),ENSG00000133136,ENSG00000182625,ENSG00000127920(GNG11)" " oogenesis stage && adult stage | female , adult stage , adult stage && oogenesis stage , adult stage | female , embryonic stage | 18-21 hr , adult stage | male , larval stage | third instar , embryonic stage | 7-12 hr " " ovary

, subesophageal ganglion

, oocyte

, adult thorax

, thorax

, embryonic brain

, head

, imaginal disc

, larval brain

, adult head

, adult abdomen

, embryonic nervous system

, optic lobe

, ventral nerve cord

, nurse cell

, adult brain

,

ubiquitous " "lethal,recessive,cell polarity defective,neurophysiology defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,taste perception defective,neuroanatomy defective,viable,visible" "embryonic pericardial cell,cardioblast,neuroblast,spindle & neuroblast,ganglion mother cell,embryonic neuroblast,embryonic/larval neuroblast,mesothoracic tergum,gastrula embryo,germline clone" FBgn0002774 mle maleless http://flybase.net/reports/FBgn0002774.html protein_coding_gene "0008026=ATP-dependent helicase activity, 0005524=ATP binding, 0003724=RNA helicase activity, 0003725=double-stranded RNA binding, 0003682=chromatin binding, 0003723=RNA binding, 0004386=helicase activity" "0007549=dosage compensation, 0016457=dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome, 0048675=axon extension, 0031453=positive regulation of heterochromatin assembly, 0008340=determination of adult lifespan, 0045433=male courtship behavior, veined wing generated song production, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0009047=dosage compensation by hyperactivation of X chromosome" "0000785=chromatin, 0005700=polytene chromosome, 0005634=nucleus, 0000228=nuclear chromosome, 0005694=chromosome, 0005737=cytoplasm, 0072487=MSL complex, 0005665=DNA-directed RNA polymerase II, core complex, 0016456=X chromosome located dosage compensation complex, transcription activating, 0000805=X chromosome" "Mle, MLE, mls, CG11680, nap[ts], maleless-no-action potential, male-lethal, male lethal, mll, no-action-potential, nap, male-killer, Maleless, mak, no action potential" "IPR007502=Helicase-associated domain, IPR011709=Domain of unknown function DUF1605, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR014720=Double-stranded RNA-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG11680 16-Dec-15 2015_12 WBGene00004355(rha-1) ENSXETG00000012515(dhx9) ENSMUSG00000042699(Dhx9) ENSG00000135829(DHX9) embryonic stage -- adult stage " adult stage | female , adult stage | male " "viable,fertile,behavior defective,recessive,heat sensitive,lethal - all die before end of larval stage,some die during third instar larval stage,male sterile,lethal,male,some die during larval stage,wild-type,partially,male limited,paralytic,chemical resistant,chemical sensitive,neurophysiology defective,short lived,song defective,neuroanatomy defective,locomotor behavior defective,poor,male fertile,partially lethal - majority live,partially lethal - majority die,some die during pupal stage" "wing,abdomen & macrochaeta,spermatozoon,heat sensitive,chromosome,embryonic/larval heart,neuromuscular junction & synapse | conditional ts,synapse | ectopic | heat sensitive,adult brain,axon & motor neuron | conditional ts,embryonic/larval neuromuscular junction,NMJ bouton,giant fiber neuron,polytene chromosome" FBgn0016736 SR3-6 Suppressor of Ras85D 3-6 http://flybase.net/reports/FBgn0016736.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052095 CG32095 http://flybase.net/reports/FBgn0052095.html "FBgn0045834, FBgn0046807" protein_coding_gene "BcDNA:GH03217, PIF-like gene 3, DPLG3, BEST:GH03217" IPR027806=Harbinger transposase-derived nuclease domain CG32095 16-Dec-15 2015_12 "ENSDARG00000054117,ENSDARG00000058874(zgc:113227),ENSDARG00000067963,ENSDARG00000052288,ENSDARG00000027676(LOC100334834),ENSDARG00000052286,ENSDARG00000067592" ENSXETG00000020129() viable FBgn0030328 Amun Amun http://flybase.net/reports/FBgn0030328.html "FBgn0043369, FBgn0066859, FBgn0066860, FBgn0066861" protein_coding_gene "0048749=compound eye development, 0022416=chaeta development, 0035220=wing disc development" 0005634=nucleus "anon-WO03040301.104, anon-WO03040301.107, anon-WO03040301.105, CG2446, EP1503" CG2446 16-Dec-15 2015_12 ENSDARG00000004274(zgc:112496) "visible,body color defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,neuroanatomy defective,lethal,recessive" "eye,macrochaeta & mesothoracic tergum | supernumerary-537.4,macrochaeta & mesothoracic tergum | ectopic-537.4,macrochaeta & mesothoracic tergum-537.4,macrochaeta & mesothoracic tergum | supernumeraryptc-559.1,macrochaeta & mesothoracic tergum | ectopicptc-559.1,macrochaeta & mesothoracic tergumptc-559.1,microchaeta & mesothoracic tergumsr-md710,microchaeta & mesothoracic tergumpnr-MD237,trichogen cell,mesothoracic tergum,neuron & mesothoracic tergum primordium | pupal stagepnr-MD237,trichogen cell & mesothoracic tergum primordium | pupal stagepnr-MD237,sensory mother cell & mesothoracic tergum primordium | pupal stagepnr-MD237,microchaeta & mesothoracic tergum | somatic clone,tormogen cell,scutellar bristle,ectopic" DRSC28058 K 0.003791622 0.983694793 0.37657063 -0.095783708 0.802718505 1.831132343 FBgn0067306 D10 D10 http://flybase.net/reports/FBgn0067306.html gene 16-Dec-15 2015_12 "visible,partially lethal - majority die,viable" ommatidium FBgn0038197 foxo "forkhead box, sub-group O" http://flybase.net/reports/FBgn0038197.html FBgn0062059 protein_coding_gene "0003690=double-stranded DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0019901=protein kinase binding, 0043565=sequence-specific DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0008301=DNA binding, bending, 0008134=transcription factor binding, 0031490=chromatin DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0001558=regulation of cell growth, 0001578=microtubule bundle formation, 0006171=cAMP biosynthetic process, 0045475=locomotor rhythm, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006697=ecdysone biosynthetic process, 0001745=compound eye morphogenesis, 0010888=negative regulation of lipid storage, 0045893=positive regulation of transcription, DNA-templated, 0006974=cellular response to DNA damage stimulus, 0040015=negative regulation of multicellular organism growth, 0007623=circadian rhythm, 0042594=response to starvation, 1900078=positive regulation of cellular response to insulin stimulus, 0007476=imaginal disc-derived wing morphogenesis, 0034599=cellular response to oxidative stress, 0008340=determination of adult lifespan, 0045792=negative regulation of cell size, 0040014=regulation of multicellular organism growth, 0009617=response to bacterium, 0032925=regulation of activin receptor signaling pathway, 0009267=cellular response to starvation, 0005977=glycogen metabolic process, 0016241=regulation of macroautophagy, 0007389=pattern specification process, 0046626=regulation of insulin receptor signaling pathway, 0006979=response to oxidative stress, 0035206=regulation of hemocyte proliferation, 0008285=negative regulation of cell proliferation, 0007520=myoblast fusion, 0036099=female germ-line stem cell maintenance, 0040008=regulation of growth, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0048813=dendrite morphogenesis, 0008286=insulin receptor signaling pathway, 0046627=negative regulation of insulin receptor signaling pathway, 2000253=positive regulation of feeding behavior, 0009888=tissue development, 0010506=regulation of autophagy, 0000122=negative regulation of transcription from RNA polymerase II promoter, 2000130=positive regulation of octopamine signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0046620=regulation of organ growth, 0040027=negative regulation of vulval development, 0007525=somatic muscle development, 0034198=cellular response to amino acid starvation" "0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus, 0005667=transcription factor complex" "3143, Q95V55, forkhead box, subgroup O, foxO, forkhead box-containing protein, O subfamily, DmQ95V5, forkhead transcription factor, FOXO1, dFoxo, foxo|dFOXO, dFOXO, fd88A, Forkhead box O, Foxo, anon-WO0118547.374, Forkhead bOX-containing protein, subfamily O, dFoxO, cg3143, dfoxo, Forkhead Box O, CG3143, FoxO, FKHR, Afx, Dfoxo, FOXO, Forkhead box type O, Forkhead box, forkhead box sub-group O" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain" CG3143 16-Dec-15 2015_12 "ENSDARG00000061549(foxo1b),ENSDARG00000063540(foxo1a),ENSDARG00000023058(foxo3a),ENSDARG00000042904(foxo3b),ENSDARG00000055792,ENSDARG00000024619(si:ch211-206a7.2)" "ENSXETG00000020899(FOXO4),ENSXETG00000014847(FOXO3),ENSXETG00000012944(FOXO6),ENSXETG00000016048(foxo1a)" "ENSMUSG00000044167(Foxo1),ENSMUSG00000048756(Foxo3),ENSMUSG00000042903(Foxo4),ENSMUSG00000052135(Foxo6)" "ENSG00000118689(FOXO3),ENSG00000150907(FOXO1),ENSG00000184481(FOXO4),ENSG00000204060" "decreased cell number,viable,fertile,visible,neuroanatomy defective,stress response defective,aging defective,short lived,nutrition conditional,developmental rate defective,small body,oxidative stress response defective,circadian rhythm defective,immune response defective,increased cell death,long lived,RU486 conditional,locomotor behavior defective,body size defective,mitotic cell cycle defective,chemosensitive behavior defective,female,female fertile,reduced,chemical resistant,wild-type,lethal - all die before end of larval stage,some die during larval stage,feeding behavior defective,lethal,heat sensitive,decreased cell size,somatic clone,starvation stress response defective,male limited,temperature response defective" "germarium cap cell,embryonic/larval neuromuscular junction,type I bouton,microtubule,wing,segment border muscle,A1-7 dorsal acute muscle 1,embryonic/larval somatic muscle,embryonic myoblast,eye,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,muscle cell,supernumerary,synaptic vesicle,ommatidium,mushroom body neuroblast,eye disc,adult heart,neurite | pharate adult stage,retina,adult brain,abdominal adult fat mass,microtubuleRapGAP1-OK6,anterior crossvein,interommatidial bristle,wing cell,embryonic/larval neuroblast,adult gut,heat sensitive,adult anterior midgut epithelium,embryonic/larval fat body,somatic clone,synaptic vesicleRapGAP1-OK6,bouton,dorsal appendage,drug conditional,chorion,microtubuleD42,adult,intestinal stem cell,microtubuleelav.PLu" DRSC13017 K -2.306068294 -0.355575985 FBgn0053523 Vap-33B VAMP-associated protein of 33kDa ortholog B http://flybase.net/reports/FBgn0053523.html "FBgn0035650, FBgn0035651, FBgn0052410, FBgn0064970, FBtr0077033, FBpp0076741, FBtr0077034, FBpp0076742, FBtr0077035, FBpp0076743, FBtr0077036, FBpp0076744" protein_coding_gene 0022008=neurogenesis 0012505=endomembrane system "CG32410, CG10727, BcDNA:GH09028, CG10977, MSP protein, CG33523" "IPR001251=CRAL-TRIO lipid binding domain, IPR000535=Major sperm protein (MSP) domain, IPR008962=PapD-like, IPR011074=CRAL/TRIO, N-terminal domain" CG33523 16-Dec-15 2015_12 ENSDARG00000026024(mospd2) WBGene00015148(B0336.11) ENSXETG00000009990(mospd2) ENSMUSG00000061778 ENSG00000130150(MOSPD2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,anterior fascicle & synapse,intersegmental nerve" FBgn0000382 csw corkscrew http://flybase.net/reports/FBgn0000382.html "FBgn0004637, FBgn0026663, FBgn0029599, FBgn0066824, FBgn0066826, FBgn0066827" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0004726=non-membrane spanning protein tyrosine phosphatase activity, 0004728=receptor signaling protein tyrosine phosphatase activity, 0005515=protein binding" "0007362=terminal region determination, 0045500=sevenless signaling pathway, 0006911=phagocytosis, engulfment, 0045314=regulation of compound eye photoreceptor development, 0006470=protein dephosphorylation, 0008543=fibroblast growth factor receptor signaling pathway, 0007424=open tracheal system development, 0043066=negative regulation of apoptotic process, 0007173=epidermal growth factor receptor signaling pathway, 0007418=ventral midline development, 0016311=dephosphorylation, 0007444=imaginal disc development, 0007428=primary branching, open tracheal system, 0008595=anterior/posterior axis specification, embryo, 0008293=torso signaling pathway, 0007498=mesoderm development, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0000278=mitotic cell cycle, 0007427=epithelial cell migration, open tracheal system, 0007465=R7 cell fate commitment" 0005737=cytoplasm "SHP-2, Enhancer of sevenless 1A, 19-106, l(1)2Dd, anon-WO03040301.219, Corkscrew, CG3954, EG:BACN25G24.2, l(1)2Db, l(1)GA114, E(sev)1A, Shp2/csw, l(1)G0170, anon-WO03040301.207, CSW, csw/SHP-2, anon-WO03040301.209, Csw/Shp2, Shp-2, l(1)csw, Csw" "IPR000980=SH2 domain, IPR000242=PTP type protein phosphatase, IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain" CG3954 16-Dec-15 2015_12 "ENSDARG00000012340(zgc:63553),ENSDARG00000020334(LOC100330785),ENSDARG00000013916(ptpn6)" YER075C(PTP3) WBGene00004214(ptp-2) "ENSXETG00000001760(BC089648.1),ENSXETG00000004305(PTPN11),ENSXETG00000023918(PTPN6)" "ENSMUSG00000043733(Ptpn11),ENSMUSG00000004266(Ptpn6)" "ENSG00000179295(PTPN11),ENSG00000111679(PTPN6)" " embryonic stage | late , larval stage--adult stage , embryonic stage "

ubiquitous "visible,somatic clone,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,wild-type,dominant,increased cell death,germline clone,rescuable maternal effect,maternal effect,viable,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" "tarsal segment,wing vein L5,ommatidium,interommatidial bristle,eye,somatic clone,eye disc,chromosome & larval neuroblast,metaphase,eye photoreceptor cell,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R7,photoreceptor cell,precursor,outer photoreceptor cell,mesoderm,germline clone,embryonic/first instar larval cuticle,neurogenic region,tracheal precursor cell,embryonic epidermis,posterior,embryo,maternal effect,embryonic head,photoreceptor,egg chamber,chorion | maternal effect | somatic clone,amnioproctodeal invagination,Malpighian tubule primordium,commissure,longitudinal connective,arista,unguis,A1-7 dorsal acute muscle 1,A1-7 ventral acute muscle 2,wing vein,chorion | maternal effect,denticle belt,extended germ band embryo,distal,wing vein L2,wing vein L4,dorsal appendage,embryonic/larval pericardial cell,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval midgut,ectopic,wing,crossvein,trichogen cell,mesothoracic tergum" DRSC18756 IK -1.266121735 -2.893023686 -0.059697079 -0.111770866 -3.561355118 -3.747142596 FBgn0029123 SoxN SoxNeuro http://flybase.net/reports/FBgn0029123.html "FBgn0010277, FBgn0032070" protein_coding_gene "0005515=protein binding, 0031490=chromatin DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity" "0007411=axon guidance, 0030111=regulation of Wnt signaling pathway, 0007417=central nervous system development, 0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "Sox-neuro, DM64, Sox B1, SOX29F, Sry-related DM64, soxneuro, Sry-rDM64, Sox-Neuro, CG18024, SOXB1, soxN" "IPR031268=Transcription factor SOX-1, IPR009071=High mobility group box domain, IPR022097=Transcription factor SOX" CG18024 16-Dec-15 2015_12 "ENSDARG00000008131(sox1b),ENSDARG00000069866(sox1a),ENSDARG00000070913(sox2),ENSDARG00000053569(sox3),ENSDARG00000040266(sox19b),ENSDARG00000060801" YKL032C(IXR1) WBGene00004771(sem-2) "ENSXETG00000001902(SOX1),ENSXETG00000026292(sox2),ENSXETG00000007607(sox3)" "ENSMUSG00000079994(Sox1),ENSMUSG00000045179(Sox3),ENSMUSG00000074637(Sox2)" "ENSG00000182968(SOX1),ENSG00000134595(SOX3),ENSG00000181449(SOX2)" " embryonic stage | stage 10 , embryonic stage | stage 12 , embryonic stage | stage 8 " " ventral neurogenic region

, ventral nerve cord primordium && embryonic central nervous system | restricted

, ventral nerve cord primordium

" " embryonic stage | stage 10 , embryonic stage | stage 12 , embryonic stage | stage 8 " " ventral nerve cord primordium

, ventral nerve cord primordium | restricted && central nervous system | restricted

, ventral neurogenic region

" "neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage,lethal" "denticle,ectopic,cell autonomous,embryonic head,midgut constriction,denticle belt,RP2 motor neuron,EL neuron,aCC neuron,pCC neuron,ganglion mother cell,stage 1 neuroblast,neuroblast NB3-5,neuroblast NB2-5,neuroblast NB5-3,neuroblast NB3-2,neuroblast NB5-6,neuroblast NB7-4,neuroblast NB2-2,neuroblast NB4-2,neuroblast NB6-2,neuroblast NB7-2,neuroblast NB3-1,neuroblast NB4-1,neuroblast NB6-1,neuroblast NB6-4,stage 2 neuroblast,stage 3 neuroblast,stage 4 neuroblast,stage 5 neuroblast,neuroblast NB2-1,neuroblast NB2-4,neuroblast NB3-3,neuroblast NB4-4,neuroblast NB5-4,neuroblast NB5-1,neuroblast NB4-3,neuroblast NB5-5,neuroblast NB7-3,neuroblast NB1-1,neuroblast MP2,neuroblast NB5-2,embryonic/first instar larval cuticle,axon & ventral nerve cord,anterior commissure,posterior commissure,longitudinal connective,commissure,extended germ band embryo,embryonic/larval neuron,EG neuron,embryonic/larval glial cell,neuroblast NB7-1,embryonic neuroblast,U neuron,connective,adult head,axon & ventral nerve cordelav.PLu,wing,thorax,leg,eye,denticle row" FBgn0005198 gig gigas http://flybase.net/reports/FBgn0005198.html protein_coding_gene "0004679=AMP-activated protein kinase activity, 0019900=kinase binding, 0005096=GTPase activator activity, 0005515=protein binding" "0006974=cellular response to DNA damage stimulus, 0007584=response to nutrient, 0001934=positive regulation of protein phosphorylation, 0008340=determination of adult lifespan, 0030178=negative regulation of Wnt signaling pathway, 0043491=protein kinase B signaling, 0048477=oogenesis, 0030308=negative regulation of cell growth, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0046627=negative regulation of insulin receptor signaling pathway, 0051726=regulation of cell cycle, 0048009=insulin-like growth factor receptor signaling pathway, 0046621=negative regulation of organ growth, 0038202=TORC1 signaling, 1902350=cellular response to chloroquine, 0006909=phagocytosis, 0042325=regulation of phosphorylation, 0006629=lipid metabolic process, 0071456=cellular response to hypoxia, 0035069=larval midgut histolysis, 0010508=positive regulation of autophagy, 0046331=lateral inhibition, 0007165=signal transduction, 0043547=positive regulation of GTPase activity, 0045792=negative regulation of cell size, 0008285=negative regulation of cell proliferation, 2000331=regulation of terminal button organization, 0032007=negative regulation of TOR signaling" "0033596=TSC1-TSC2 complex, 0005737=cytoplasm, 0005634=nucleus" "Gigas, gigas, Tsc2/gig, ME 109, TSC2, lethal(3)109, dTsc2, gig|Tsc2, tsc2, l(3)109, Tuberous sclerosis complex 2, 6975, dTSC2, CG6975, C1, Tsc2" "IPR018515=Tuberin-type domain, IPR003913=Tuberin, IPR024584=Tuberin, N-terminal, IPR016024=Armadillo-type fold, IPR000331=Rap GTPase activating protein domain" CG6975 16-Dec-15 2015_12 ENSXETG00000015935(TSC2) ENSMUSG00000002496(Tsc2) ENSG00000103197(TSC2) "size defective,wild-type,visible,recessive,lethal - all die before end of larval stage,some die during larval stage,melanotic mass phenotype,lethal,neuroanatomy defective,smell perception defective,somatic clone,increased cell size,decreased cell number,cell autonomous,cell non-autonomous,grooming behavior defective,large body,decreased cell growth,decreased cell death,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,body color defective,partially lethal - majority die" "oocyte,germline clone,eye,ommatidium,wing,wing margin bristle,photoreceptor cell,cone cell,pigment cell,interommatidial bristle,rhabdomere,antenna,somatic clone,adult antennal nerve,antennal lobe,antennal lobe glomerulus V,microchaeta,macrochaeta,mesothoracic tergum,anterior scutellar bristle & neuron | somatic clone,anterior notopleural bristle & neuron | somatic clone,posterior notopleural bristle & neuron | somatic clone,humeral bristle & neuron | somatic clone,vertical bristle & neuron | somatic clone,embryonic/larval neuromuscular junction,NMJ bouton,cell cycle,eye disc,wing disc,eye disc & S phase | ectopic | somatic clone,eye disc & mitotic cell cycle | ectopic | somatic clone,intestinal stem cell,enteroendocrine cell,embryonic/larval neuromuscular junction | third instar larval stage,chaeta,supernumerary,trichogen cell,embryonic/larval fat body,somatic clone | third instar larval stage" DRSC11351 I 0.432825097 -1.781679599 0.212737057 0.312569377 -0.801507522 -0.471950549 FBgn0000229 bsk basket http://flybase.net/reports/FBgn0000229.html "FBgn0015248, FBgn0032199" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0004707=MAP kinase activity, 0004705=JUN kinase activity, 0005515=protein binding, 0005524=ATP binding" "0071907=determination of digestive tract left/right asymmetry, 0000165=MAPK cascade, 0009408=response to heat, 0048812=neuron projection morphogenesis, 0071243=cellular response to arsenic-containing substance, 0034614=cellular response to reactive oxygen species, 0034599=cellular response to oxidative stress, 0007254=JNK cascade, 0043652=engulfment of apoptotic cell, 0035313=wound healing, spreading of epidermal cells, 0046844=micropyle formation, 0048675=axon extension, 0048674=collateral sprouting of injured axon, 0006979=response to oxidative stress, 0001736=establishment of planar polarity, 0006952=defense response, 0007258=JUN phosphorylation, 0009267=cellular response to starvation, 0048615=embryonic anterior midgut (ectodermal) morphogenesis, 0042060=wound healing, 0006468=protein phosphorylation, 0046529=imaginal disc fusion, thorax closure, 0035006=melanization defense response, 0048666=neuron development, 0016055=Wnt signaling pathway, 0048803=imaginal disc-derived male genitalia morphogenesis, 0046843=dorsal appendage formation, 0019731=antibacterial humoral response, 0043508=negative regulation of JUN kinase activity, 0007391=dorsal closure, 0030707=ovarian follicle cell development, 0007411=axon guidance, 0010508=positive regulation of autophagy, 0007298=border follicle cell migration, 0071276=cellular response to cadmium ion" "0030424=axon, 0030425=dendrite" "BSK, Jun N-terminal kinase, DJNK, jnk, DBSK/JNK, D-JNK, Jun-kinase, pJNK, c-Jun-N-terminal Kinase, SAPKa, c-Jun N-terminal kinase, Jun kinase, Basket, DJNK/bsk, Bsk, CG5680, c-Jun aminoterminal kinase, Jnk, D-junk, dJNK, JUN kinase, JNK/SAPK, Jun N-terminal Kinase, Jun NH2-terminal Kinase, JNK, Junk, Jun-N-terminal Kinase" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008351=Mitogen-activated protein (MAP) kinase, JNK, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG5680 16-Dec-15 2015_12 "ENSDARG00000025747(mapk10),ENSDARG00000009870(LOC100333971),ENSDARG00000031888(zgc:172209)" WBGene00002178(jnk-1) "ENSXETG00000006199(MAPK10),ENSXETG00000021691(MAPK8)" "ENSMUSG00000046709(Mapk10),ENSMUSG00000021936(Mapk8),ENSMUSG00000020366(Mapk9)" "ENSG00000109339(MAPK10),ENSG00000107643(MAPK8),ENSG00000050748(MAPK9)" " adult stage | male , embryonic stage | stage 6,7 , adult stage | female , larval stage | third instar , embryonic stage , embryonic stage && larval stage && pupal stage ,, embryonic stage | early , embryonic stage | stage >=8 " " posterior transverse furrow

, dorsal mesothoracic disc

, embryonic epidermis

, embryonic central nervous system

, embryonic peripheral nervous system

, fat body

, imaginal disc

, eye disc

, cephalic furrow

, anterior transverse furrow

,

ubiquitous , hemocyte

, embryonic brain

" "neuroanatomy defective,somatic clone,cell death defective,nutrition conditional,viable,fertile,chemical sensitive,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,progressive,visible,wound healing defective,lethal,neurophysiology defective,planar polarity defective,stress response defective,RU486 conditional,conditional,long lived,oxidative stress response defective,starvation stress response defective,increased cell death,decreased cell growth,chemical resistant,short lived,heat sensitive" "Kenyon cell,somatic clone,axon | somatic clone,egg chamber,nutrition conditional,follicle cell,nurse cell,embryonic epidermis,dorsal,embryonic/first instar larval cuticle,axon & dorsal cluster neuron | somatic clone,stage 13 embryo,stage 14 embryo,stage 15 embryo,filamentous actin,amnioserosa,embryonic dorsal epidermis,anterior,neuroblast,progressive,alpha/beta Kenyon cell,gamma Kenyon cell,photoreceptor cell,ommatidium,embryo,axon | pupal stage | somatic clone,tract,dorsal closure embryo,germline clone,eye,lamina,neuron,eye photoreceptor cell,wing disc,thorax,medulla,axon & dorsal cluster neuronato.3.6,axoney-OK107,embryonic leading edge cell,embryonic abdominal segment,male genitalia,adult thorax,peripodial epithelium,embryonic/larval hemolymph | third instar larval stage,mesothoracic cleft,ectopic,bouton,neuromuscular junction | larval stage,synapse,segmental nerve,conditional,adult gut,RU486 conditional,autophagic vacuole | third instar larval stage | chemical conditional,embryonic/larval gut,chemical conditional,adult,embryonic/larval fat body,ventral furrow,intestinal stem cell,mesothoracic tergum,heat sensitive" FBgn0265575 yin yin http://flybase.net/reports/FBgn0265575.html "FBgn0015565, FBgn0085365, FBgn0024847" protein_coding_gene 0005427=proton-dependent oligopeptide secondary active transmembrane transporter activity 0006857=oligopeptide transport 0005887=integral component of plasma membrane "CG2913, EG:EG0002.1, OPT1, oligopeptide transporter 1, CG34336, OpT1, CG44402, opt, opt1, Yin" "IPR000109=Proton-dependent oligopeptide transporter family, IPR018456=PTR2 family proton/oligopeptide symporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR004768=Oligopeptide transporter" CG44402 16-Dec-15 2015_12 "ENSDARG00000044528(slc15a1b),ENSDARG00000032010(slc15a2)" YKR093W(PTR2) "WBGene00003876(pept-2),WBGene00003877(pept-1)" ENSXETG00000012024(SLC15A2) "ENSMUSG00000022899(Slc15a2),ENSMUSG00000025557(Slc15a1)" "ENSG00000163406(SLC15A2),ENSG00000088386(SLC15A1)" " adult stage | female , adult stage , adult stage && oogenesis stage | stage S10-11 , embryonic stage -- adult stage , adult stage && oogenesis stage , spermatogenesis && adult stage , embryonic stage | <3 hr , adult stage && oogenesis stage | stage >=S11 " " seminal receptacle

, nurse cell

, posterior adult hindgut | restricted

, ovary

, primary spermatocyte cyst | restricted

, adult midgut | restricted

, spermathecal duct

, oviduct

, adult head

, oocyte

" " adult stage , spermatogenesis && adult stage , adult stage && oogenesis stage | stage S9-14 , embryonic stage " " adult antennal nerve

, primary spermatocyte cyst | restricted

, oocyte

, mushroom body alpha-lobe

, oviduct

, adult fat body

, adult midgut | restricted

, spermathecal duct

, posterior adult hindgut | restricted

, yolk

, uterus

, neuropil

, adult rectal papilla | basal

, seminal receptacle

" FBgn0025800 Smox Smad on X http://flybase.net/reports/FBgn0025800.html "FBgn0024186, FBgn0024304, FBgn0040171" protein_coding_gene "0005515=protein binding, 0005072=transforming growth factor beta receptor, cytoplasmic mediator activity, 0031490=chromatin DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007411=axon guidance, 0007476=imaginal disc-derived wing morphogenesis, 0006355=regulation of transcription, DNA-templated, 0048666=neuron development, 0007179=transforming growth factor beta receptor signaling pathway, 0048813=dendrite morphogenesis, 0010507=negative regulation of autophagy, 0090256=regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis, 0016319=mushroom body development, 0008340=determination of adult lifespan, 0007346=regulation of mitotic cell cycle" 0005667=transcription factor complex "DSMAD2, sisters against dpp, Smad, Sad, dSmad2, dsmad2, Smad2, l(1)G0348, temporarily deranged, dSMAD2, Smox/dSmad2, SMOX, smad2, DSmad2, ted, smox, CG2262, Sisters against dpp, SMAD2, SmoX, sad, tmp" "IPR001132=SMAD domain, Dwarfin-type, IPR008984=SMAD/FHA domain, IPR013790=Dwarfin, IPR017855=SMAD domain-like, IPR013019=MAD homology, MH1, IPR003619=MAD homology 1, Dwarfin-type" CG2262 16-Dec-15 2015_12 "ENSDARG00000036096(smad3a),ENSDARG00000010207(smad3b),ENSDARG00000006389(smad2)" WBGene00004856(sma-2) ENSXETG00000020292(Q5U4Q3_XENTR) "ENSMUSG00000032402(Smad3),ENSMUSG00000024563(Smad2)" "ENSG00000166949(SMAD3),ENSG00000175387(SMAD2)" " embryonic stage -- adult stage , larval stage | third instar , adult stage | female , embryonic stage | stage >=6 , embryonic stage , embryonic stage | pre-blastoderm , embryonic stage | 0-2 hr " " imaginal disc

, mesoderm

, larval brain | restricted

, organism

" "neuroanatomy defective,germline clone,long lived,flight defective,progressive,RU486 conditional,visible,partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,cell growth defective,size defective,mitotic cell cycle defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,decreased cell size,lethal,viable,fertile" "abdominal segmental nerve,germline clone,adult somatic muscle,progressive,lysosome | progressiveMhc.PW,autophagic vacuoleMhc.PW,wing,chaeta,embryonic/larval anal pad,embryonic/larval brain,axon & eye photoreceptor cell,lamina anlage glial cell,medulla neuropil glial cell,larval inner optic anlage,larval outer optic anlage,gamma-lobe & neuron | somatic clone,gamma-lobe & dendrite | somatic clone,photoreceptor cell R7 & axon,photoreceptor cell R8 & axon,lamina,medulla neuropil,dorsal cluster neuron & axon | somatic clone,dorsal cluster neuron & neurite | somatic clone,protocerebrum,somatic clone,optic lobe,fascicle,photoreceptor cell R7,dorsal cluster neuron,wing disc,transmedullary neuron Tm20,wing blade,wing disc | larval stage,wing disc | third instar larval stage" DRSC18716 I -0.139699492 2.03074549 0.635918563 -1.243442561 0.248026268 -0.602609689 FBgn0000411 D Dichaete http://flybase.net/reports/FBgn0000411.html "FBgn0010271, FBgn0010273, FBgn0010274, FBgn0010275, FBgn0010276, FBgn0013641, FBgn0014030" protein_coding_gene "0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003730=mRNA 3'-UTR binding, 0003700=sequence-specific DNA binding transcription factor activity" "0060810=intracellular mRNA localization involved in pattern specification process, 0007411=axon guidance, 0007442=hindgut morphogenesis, 0007420=brain development, 0009950=dorsal/ventral axis specification, 0002168=instar larval development, 0014019=neuroblast development, 0007417=central nervous system development, 0035120=post-embryonic appendage morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0007350=blastoderm segmentation, 0010468=regulation of gene expression, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045893=positive regulation of transcription, DNA-templated, 0070983=dendrite guidance, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005737=cytoplasm" "Sry-rDM10, DM23, DM63, Sry-rDM36, DM10, dichaete, Sry-rDM33, fish, Sry-related DM10, l(3)LG9, Sry-rDM23, Sox70D, fish hook, SOXB2.1, Sry-related DM63, loD, Sry-related DM33, Sry-rDM63, Sox70, SOXDP, Sox box protein 70D, DM33, DM36, Fish-Hook, SOX70, Sry-related DM36, CG5893, lethal of Dichaete, Sry-related DM23, SOX70D, Sox B2-1, fish-hook" IPR009071=High mobility group box domain CG5893 16-Dec-15 2015_12 WBGene00004949(sox-2) " embryonic stage | stage 6 , embryonic stage | embryonic cycle 13 , embryonic stage | stage 13 , embryonic stage | embryonic cycle 14 , embryonic stage | extended germ band , embryonic stage | stage 6-8 , embryonic stage | early , embryonic stage | stage 4 " " ventral neurogenic region | restricted

, organism | 10-70% egg length

, embryonic brain

, embryonic/larval hindgut

,

50% egg length , ventral neurogenic region | medial

, organism | 10-30% egg length

, ventral nerve cord | restricted

, embryonic/larval pharynx

, procephalic neurogenic region

" "viable,fertile,neuroanatomy defective,visible,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,germline clone,partially lethal - majority die,eye color defective,some die during pupal stage,partially lethal - majority live" "wing,proximal,wing vein L3,medial costal vein,alula,embryonic/larval central nervous system,commissure | embryonic stage,tract | embryonic stage,longitudinal connective | embryonic stage,axon | embryonic stagesim.P3.7,axon | embryonic stagepros.C20,posterior,wing hinge,embryonic segment,embryonic head,ventral nerve cord commissure,longitudinal connective,midline glial cell,RP2 motor neuron,supernumerary,aCC neuron,pCC neuron,EL neuron,neuroblast NB5-3,embryonic epidermis,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,neuroblast NB6-1,neuroblast NB4-1,first segment of antenna,somatic clone,adult cuticle & adult head | somatic clone,tibia,tarsal segment,presumptive embryonic/larval central nervous system,neuroblast NB1-1,dorsal appendage,germline clone,chorion | germline clone,embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 4,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,anterior,abdominal segment,denticle belt,larval hindgut & embryo & cellfz-GS1a),hindgut,embryonic tritocerebrum,embryonic deuterocerebrum,sensillum campaniformium of dorsal radius Sc25,sensillum campaniformium of dorsal radius Sc12,sensillum campaniformium of ventral radius Sc5,haltere,macrochaeta & adult thorax,eye,ommatidium,interommatidial bristle,leg,arista,third segment of antenna,pigment cell,eye-antennal disc,antenna,macrochaeta,ectopic,tarsal segment 2,tarsal segment 3,tarsal segment 4,distal,morphogenetic furrow,anterior commissure,posterior commissure,trichogen cell,mesothoracic tergum,adult antennal lobe projection neuron,dendrite,axon,local interneuron of adult antennal lobe,adult olfactory receptor neuron Or47b,adult olfactory receptor neuron Or88a" FBgn0039234 nct nicastrin http://flybase.net/reports/FBgn0039234.html FBgn0043964 protein_coding_gene "0016485=protein processing, 0007219=Notch signaling pathway, 0007010=cytoskeleton organization, 0007220=Notch receptor processing, 0045463=R8 cell development, 0046331=lateral inhibition, 0006509=membrane protein ectodomain proteolysis, 0008594=photoreceptor cell morphogenesis, 0045314=regulation of compound eye photoreceptor development" "0070765=gamma-secretase complex, 0055037=recycling endosome, 0005770=late endosome, 0005886=plasma membrane, 0016021=integral component of membrane" "Nic, dNicastrin, CG7012, agoraphobic, ST96B, Nicastrin, nic, Nct, S5A, agro, dNct" IPR008710=Nicastrin CG7012 16-Dec-15 2015_12 WBGene00000148(aph-2) ENSXETG00000027247(NCSTN) ENSMUSG00000003458(Ncstn) ENSG00000162736(NCSTN) "viable,visible,lethal,recessive,germline clone,neurogenic phenotype,wild-type,lethal - all die before end of larval stage,some die during larval stage,partially lethal,somatic clone,increased cell number,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell number" "eye,embryonic epidermis,germline clone,presumptive embryonic/larval nervous system,wing,somatic clone,wing vein,wing disc,wing margin,wing margin bristle,follicle cell,oocyte,cell non-autonomous,germinal vesicle | cell non-autonomous,cytoskeleton & follicle cell | somatic clone,larva,sensory mother cell & dorsal mesothoracic disc,presumptive embryonic/larval central nervous system,microchaeta,neuroblast,adult head,external sensory organ precursor cell,supernumerary,antennal disc,eye disc,eye photoreceptor cell,ventral thoracic disc,photoreceptor cell R8,nucleus | somatic clone | wandering third instar larval stage" FBgn0005561 sv shaven http://flybase.net/reports/FBgn0005561.html "FBgn0003468, FBgn0003649, FBgn0004541, FBgn0020913" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0001158=enhancer sequence-specific DNA binding" "0042676=compound eye cone cell fate commitment, 0007517=muscle organ development, 0048813=dendrite morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042673=regulation of retinal cone cell fate specification, 0048666=neuron development, 0042682=regulation of compound eye cone cell fate specification, 0045676=regulation of R7 cell differentiation, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Dpax-2, dPax2, DPax-2, Sv, D-pax-2, spa-sv, d-Pax2, pax2/sparkling, Sparkling, poliert, DPax2, Cat, D-pax2, D-Pax2, PAX2, Pax2/5/8, l(4)40, Pax258, Shaven, sparkling poliert, sparklin poliert, Dpax2, shaven/sparkling, sparkling, pol, en(lz)4G/I, dPax258, Pax2, CG11049, Cataract, spa" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001523=Paired domain, IPR009057=Homeodomain-like" CG11049 16-Dec-15 2015_12 "ENSDARG00000028148(pax2a),ENSDARG00000032578(pax2b),ENSDARG00000037383(pax5),ENSDARG00000015879" "ENSXETG00000006547(PAX5),ENSXETG00000014206(pax2),ENSXETG00000001272(PAX8)" "ENSMUSG00000014030(Pax5),ENSMUSG00000004231(Pax2),ENSMUSG00000026976(Pax8)" "ENSG00000196092(PAX5),ENSG00000075891(PAX2),ENSG00000125618(PAX8)" " larval stage , embryonic stage " " ventral nerve cord

, morphogenetic furrow | posterior to

, dorsal mesothoracic disc

, larval brain

, antennal disc

, embryonic nervous system

, eye disc

, ventral thoracic disc

, peripheral nervous system

" " pupal stage , larval stage , pupal stage | early " " mechanosensory chaeta

, cone cell | precursor

, eye disc

, primary pigment cell | precursor

" "visible,recessive,uncoordinated,sterile,behavior defective,lethal,increased cell death,wild-type,viable,dominant,fertile,cold sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,short lived,somatic clone,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,cone cell,eye photoreceptor cell,inter-ommatidial precursor cell,supernumerary,pseudocone,lens,ommatidium,interommatidial bristle,macrochaeta,scutum & macrochaeta,scutum & microchaeta,scutum & macrochaeta & trichogen cell,scutum & macrochaeta & tormogen cell,anterior dorsocentral bristle & trichogen cell,posterior dorsocentral bristle & tormogen cell,microchaeta,chaeta,scutum & microchaeta & trichogen cell,rhabdomere,primary pigment cell,pigment cell,eye disc,somatic clone,anterior dorsocentral bristle & tormogen cell,trichogen cell,thecogen cell,wing,posterior,unguis,retina,adult head,antenna,external sensory organ,ectopic,tormogen cell,scutum & macrochaeta & trichogen cell | conditional tshs.PB,scutum & macrochaeta & tormogen cell | conditional tshs.PB,head bristle & trichogen cell | conditional tshs.PB,head bristle & tormogen cell | conditional tshs.PB,orbital bristle & trichogen cell | conditional tshs.PB,scutum & microchaeta & trichogen cell | conditional tshs.PB,head bristle & trichogen cellBx-MS1096,head bristle & tormogen cellBx-MS1096,scutum & microchaeta & trichogen cellBx-MS1096,scutum & microchaeta & tormogen cellBx-MS1096,rhabdomere R7" FBgn0260618 2L1682 http://flybase.net/reports/FBgn0260618.html gene "0007427=epithelial cell migration, open tracheal system" 16-Dec-15 2015_12 "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0003733 tor torso http://flybase.net/reports/FBgn0003733.html protein_coding_gene "0004714=transmembrane receptor protein tyrosine kinase activity, 0004713=protein tyrosine kinase activity, 0005524=ATP binding" "0008293=torso signaling pathway, 0006468=protein phosphorylation, 0040015=negative regulation of multicellular organism growth, 0046777=protein autophosphorylation, 0030381=chorion-containing eggshell pattern formation, 0007369=gastrulation, 0007280=pole cell migration, 0038083=peptidyl-tyrosine autophosphorylation, 0046957=negative phototaxis, 0007552=metamorphosis, 0007362=terminal region determination, 0001709=cell fate determination, 0008595=anterior/posterior axis specification, embryo, 0007443=Malpighian tubule morphogenesis, 0006355=regulation of transcription, DNA-templated" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "spliced, Tor, splc, TOR, CG1389, torso, Torso" "IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR008266=Tyrosine-protein kinase, active site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR003961=Fibronectin type III, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG1389 16-Dec-15 2015_12 "WBGene00002200(kin-16),WBGene00002199(kin-15),WBGene00003862(old-1),WBGene00003863(old-2),WBGene00002211(kin-30),WBGene00011168(R09D1.12),WBGene00002205(kin-23),WBGene00006895(ver-2)" ENSXETG00000009382(TEK) " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >S10 , embryonic stage | early , adult stage | female , embryonic stage " " germarium

, oocyte

,

ubiquitous ,

medial , nurse cell

" " embryonic stage , embryonic stage | syncytial blastoderm " "

posterior | gradient ,

medial " "viable,fertile,neurophysiology defective,phototaxis defective,lethal,maternal effect,recessive,wild-type,partially lethal - majority die,large body,developmental rate defective,terminal phenotype,germline clone,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,female sterile,hypoactive,dominant,cold sensitive,female sterile germline-dependent,hyperactive,size defective,heat sensitive,visible,small body,male limited" "ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,abdominal segment 9,abdominal segment 10,telson,labrum,ocular segment,cephalic furrow,cephalopharyngeal skeleton,filzkorper,embryonic/larval anus,embryonic/larval posterior spiracle,germline cell,embryonic epidermis,embryonic labial segment,dorsal bridge,embryonic abdominal segment 7,embryonic abdominal segment 8,embryo,germline clone,maternal effect,stomatogastric nervous system,embryonic/larval labral segment sense organ,dorsopharyngeal organ,pharyngeal monoscolopidial chordotonal organ,embryonic/larval optic lobe,embryonic/larval brain,labral segment,embryonic/larval esophagus,embryonic/larval labral nerve,adult labral sense organ,head,abdominal segment 11,embryonic/first instar larval cuticle,embryonic labral segment,posterior midgut primordium,extended germ band embryo,embryonic head,endoderm,visceral mesoderm,posterior,denticle belt,ectopic,cold sensitive,embryonic abdominal segment,embryonic telson,embryonic anal pad,abdominal 11 anal tuft,embryonic/larval midgut,pole cell,salivary gland common duct primordium,gastrula embryo,abdomen,abdominal 8 ventral denticle belt,heat sensitive,anterior midgut primordium,embryonic abdominal segment 4,embryonic thoracic segment,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 5,abdominal segment,wing,pupa" FBgn0003145 prd paired http://flybase.net/reports/FBgn0003145.html protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0007366=periodic partitioning by pair rule gene, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005667=transcription factor complex" "Prd, Paired, PRD, pr, CG6716" "IPR001356=Homeobox domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001523=Paired domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG6716 16-Dec-15 2015_12 "ENSDARG00000010192(pax3a),ENSDARG00000028348" "ENSXETG00000018527(PAX7),ENSXETG00000007640(pax3)" "ENSMUSG00000028736(Pax7),ENSMUSG00000004872(Pax3)" "ENSG00000135903(PAX3),ENSG00000009709(PAX7)" " embryonic stage | syncytial blastoderm , embryonic stage | cellular blastoderm , embryonic stage "

segment polarity " embryonic stage | stage 4-5 , adult stage | male , embryonic stage | early , embryonic stage | stage 11 , embryonic stage | stage 7-8 , embryonic stage | stage >11 " " organism | anterior & dorsal

, male accessory gland main cell

, organism | 60-80% egg length

, embryonic maxillary segment

,

segment polarity , embryonic labial segment

, embryonic mandibular segment

, male accessory gland secondary cell

,

odd pair rule , embryonic central nervous system | restricted

, embryonic labral segment

" "pair rule phenotype,male sterile,wild-type,lethal,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "RP2 motor neuron,EL neuron,U neuron,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 2 ventral denticle belt,cuticle,denticle belt,male accessory gland,abdomen & cuticle & adult,larval midgut & embryo & epidermis,heart primordium,embryonic abdominal segment 1 & muscle founder cell,embryonic abdominal segment 3 & muscle founder cell,embryonic abdominal segment 1 & cardioblast,embryonic abdominal segment 3 & cardioblast,embryonic labial segment,embryonic/larval cuticle,cephalic furrow,prothoracic ventral denticle belt,metathoracic ventral denticle belt,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,embryonic/first instar larval cuticle & mesothoracic segment,syncytial blastoderm embryo,eye,adult head,antenna" FBgn0015396 jumu jumeau http://flybase.net/reports/FBgn0015396.html "FBgn0010887, FBgn0013264, FBgn0015660" protein_coding_gene "0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0000976=transcription regulatory region sequence-specific DNA binding, 0003682=chromatin binding, 0008301=DNA binding, bending, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048813=dendrite morphogenesis, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0048666=neuron development, 0009888=tissue development, 0007391=dorsal closure, 0050832=defense response to fungus, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007476=imaginal disc-derived wing morphogenesis, 0006325=chromatin organization, 0007389=pattern specification process, 0007000=nucleolus organization, 0051302=regulation of cell division, 0008105=asymmetric protein localization, 0035050=embryonic heart tube development, 0048749=compound eye development, 0007517=muscle organ development, 0007400=neuroblast fate determination" "0005701=polytene chromosome chromocenter, 0005634=nucleus, 0005700=polytene chromosome, 0005667=transcription factor complex, 0005730=nucleolus, 0000785=chromatin, 0000791=euchromatin" "Dmjumu, Scim31, jumu/Dom, l(3)06142, Dwhn, Jumeau, Domina, Dom, Whn, E(var)631, CG4029, l(3)06439, winged-helix nude, Jumu, winged-helix nude-like, jumeaux, 5295" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain" CG4029 16-Dec-15 2015_12 "ENSG00000176302(FOXR1),ENSG00000189299(FOXR2)" "viable,immune response defective,enhancer of variegation,dominant,suppressor of variegation,lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,fertile,some die during embryonic stage,neuroanatomy defective,heat sensitive,meiotic cell cycle defective,mitotic cell cycle defective,partially lethal - majority die,wild-type" "polytene chromosomeG61,nucleolusG61,embryonic/larval salivary gland,nucleolusSgs4.PH,euchromatinSgs4.PH,polytene chromosomeSgs4.PH,hemocyte,plasmatocyte,wing,wing margin bristle,wing margin,posterior,wing hair,wing vein L5,macrochaeta,eye,ommatidium,rhabdomere,polytene chromosome,nucleolus,RP2 motor neuron,ectopic,embryonic/larval cardial cell,embryonic head,embryo,wing disc,somatic clone,embryonic/larval neuron,mitosis & nuclear chromosome,heat sensitive,photoreceptor cell,interommatidial bristle,supernumerary,adult thoracic sensillum,wing vein,RP2sib neuron,embryonic/larval pericardial cell" DRSC16651 K 0.351399047 0.470103079 0.27236188 -1.325118169 1.497283943 1.994049592 FBgn0013263 Trl Trithorax-like http://flybase.net/reports/FBgn0013263.html "FBgn0036445, FBgn0053261, FBgn0005691, FBgn0010008, FBgn0010418, FBgn0011024, FBgn0025220" protein_coding_gene "0046872=metal ion binding, 0008134=transcription factor binding, 0005515=protein binding, 0042803=protein homodimerization activity, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0031208=POZ domain binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003682=chromatin binding" "0007549=dosage compensation, 0045892=negative regulation of transcription, DNA-templated, 0006355=regulation of transcription, DNA-templated, 0007476=imaginal disc-derived wing morphogenesis, 0007283=spermatogenesis, 0048477=oogenesis, 0035186=syncytial blastoderm mitotic cell cycle, 0051259=protein oligomerization, 0031497=chromatin assembly, 0031937=positive regulation of chromatin silencing, 0006325=chromatin organization, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0000280=nuclear division, 0045893=positive regulation of transcription, DNA-templated" "0005634=nucleus, 0000791=euchromatin, 0005721=pericentric heterochromatin, 0000785=chromatin, 0005700=polytene chromosome" "Adh transcription factor 2, trl, Adf-2, l(3)s2325, E(var)62, Trl-GAGA, Gaf, gaga, Nc70F, GAGA element, Trithorax-related, anon-EST:fe2E12, Neural conserved at 70F, CG9343, GAF, Gaga, Adf-2-519, Trithorax like, GAGA-factor, trithorax-like, anon-fast-evolving-2E12, NC70F, GAGA Factor, TRL, unnamed, Adf2, transcription-factor-Adh2, GAGA factor, CG33261, TRITHORAX-LIKE, TfGAGA/Adf-2, E(var)3-trl, GAGA transcription factor, GAGA" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR015318=Zinc finger, GAGA-binding factor, IPR011333=POZ domain, IPR007087=Zinc finger, C2H2" CG33261 16-Dec-15 2015_12 ENSXETG00000000723(NACC2) ENSG00000160877(NACC1) "partially lethal - majority die,heat sensitive,male fertile,female sterile,female semi-sterile,female sterile germline-dependent,germline clone,lethal,recessive,homeotic,semi-fertile,maternal effect,some die during embryonic stage,conditional,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,enhancer of variegation,male,viable,female,reduced,meiotic cell cycle defective,non-suppressor of variegation" "egg,dorsal appendage,ovary,egg chamber,oocyte,nurse cell,actin filament,abdominal segment 5,ectopic,abdominal segment 6,wing margin,mitosis & nuclear chromosome[-],chromatin[-],mitosis & nuclear chromosome,chromatin,wing,eye,sex comb,microchaeta & abdominal segment 6 | ectopic,imaginal disc,micropyle,denticle belt,embryo,anterior,microchaeta,somatic clone,macrochaeta,proboscis,maxillary palpus,mesothoracic tergum,adult abdominal segment 6,adult abdominal segment 5,trichogen cell" FBgn0004861 ph-p polyhomeotic proximal http://flybase.net/reports/FBgn0004861.html "FBgn0003077, FBgn0029600, FBgn0029601" protein_coding_gene "0003682=chromatin binding, 0001047=core promoter binding, 0003677=DNA binding, 0044547=DNA topoisomerase binding, 0008270=zinc ion binding, 0051087=chaperone binding, 0005515=protein binding" "0035186=syncytial blastoderm mitotic cell cycle, 0030713=ovarian follicle cell stalk formation, 0021954=central nervous system neuron development, 0035075=response to ecdysone, 0006342=chromatin silencing, 0016458=gene silencing, 0030708=germarium-derived female germ-line cyst encapsulation, 0045892=negative regulation of transcription, DNA-templated, 0000070=mitotic sister chromatid segregation" "0005730=nucleolus, 0035102=PRC1 complex, 0005634=nucleus" "dPh, ph, phm, CG18412, Ph, PhP, polyhomeotic, polyhomeotic proxima, Polyhomeotic, CG18414, Ph-p, EG:87B1.5, ph-proximal, PH, Polyhomeotic proximal, php, ph[p], Polyhomeotic Proximal, PH-p, ph-P, PHP, polyhomeotic-proximal, Polyhomeotic-proximal, ph[P]" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR012313=Zinc finger, FCS-type" CG18412 16-Dec-15 2015_12 "ENSDARG00000013224(zgc:56685),ENSDARG00000056695(phc2)" ENSXETG00000009212(PHC3) ENSMUSG00000040669(Phc1) "ENSG00000111752(PHC1),ENSG00000173889(PHC3),ENSG00000179899,ENSG00000134686(PHC2)" " adult stage && oogenesis stage | stage S1-10 , embryonic stage -- adult stage , embryonic stage | cellular blastoderm , embryonic stage , larval stage | third instar , embryonic stage | stage >=12 , adult stage && oogenesis stage , embryonic stage | blastoderm , embryonic stage | stage 8-11 " " follicle cell

,

50-90% egg length , ectoderm | striped

, ventral thoracic disc

, embryonic central nervous system

, dorsal metathoracic disc

,

ubiquitous , germarium

, nurse cell

, dorsal mesothoracic disc

,

50-80% egg length ,

10-30% egg length , eye-antennal disc

, parasegment | restricted

, germ band

" " larval stage | third instar , embryonic stage | late , embryonic stage " " eye-antennal disc

, dorsal mesothoracic disc

, sensillum campaniformium

, embryonic peripheral nervous system

, dorsal metathoracic disc

, ventral thoracic disc

, cell body

,

ubiquitous , embryonic central nervous system

" "visible,recessive,homeotic,viable,mitotic cell cycle defective,partially lethal - majority die,lethal,wild-type,neuroanatomy defective,somatic clone,eye color defective,dominant,suppressor of variegation,heat sensitive,some die during pupal stage,tumorigenic,neoplasia,large body,developmental rate defective,small body,lethal - all die before end of pupal stage" "sex comb,mesothoracic leg,metathoracic leg,abdominal segment 6,ovary,interfollicle cell,egg chamber,germarium region 2b,germarium region 3,germline cyst,wing,haltere,ectopic,germarium,polar follicle cell,wing disc,eye,optic lobe neuron,somatic clone,Kenyon cell,antennal lobe,dorsal cluster neuron,ellipsoid body,genitalia,anaphase | embryonic stage,telophase | embryonic stage,nucleus | embryonic stage,posterior compartment,abdominal segment 1,abdominal segment 4,humerus,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,adult abdominal segment 4,adult abdominal segment 5,larval abdominal segment 4,larval abdominal segment 5,prothoracic leg,sex comb tooth,mesothoracic leg & sex comb | ectopic,wing disc posterior compartment,heat sensitive,mouth hooks,pupa" FBgn0004618 gl glass http://flybase.net/reports/FBgn0004618.html "FBgn0001107, FBgn0002960, FBtr0083584, FBpp0083005, FBtr0083585, FBpp0083006" protein_coding_gene "0046872=metal ion binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0035271=ring gland development, 0043153=entrainment of circadian clock by photoperiod, 0007605=sensory perception of sound, 0009649=entrainment of circadian clock, 0006355=regulation of transcription, DNA-templated, 0010114=response to red light, 0001752=compound eye photoreceptor fate commitment, 0060086=circadian temperature homeostasis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042051=compound eye photoreceptor development" 0005634=nucleus "E(sina)5, none, Glass, Gla, glass, SY3-3, no-ocelli--narrow-eyes, rh, CG7672, Enhancer of seven in absentia 5, gla, Suppressor of GMR-sina 3-2, rauhig, GLASS, SS3-2" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG7672 16-Dec-15 2015_12 "ENSMUSG00000054715(Zscan22),ENSMUSG00000061894(Zscan20),ENSMUSG00000024276(Zfp397),ENSMUSG00000024274(Zfp397os),ENSMUSG00000037017(Zscan21),ENSMUSG00000021327(Zkscan3),ENSMUSG00000025602(Zfp202),ENSMUSG00000054931(Zkscan4),ENSMUSG00000030757(Zkscan2),ENSMUSG00000029729(Zkscan1),ENSMUSG00000036721(Zscan12),ENSMUSG00000029627(Zkscan14),ENSMUSG00000063894(Zfp192),ENSMUSG00000022228,ENSMUSG00000030380(Mzf1),ENSMUSG00000021514(Zfp369),ENSMUSG00000063488(Zfp167),ENSMUSG00000070420(Zfp498),ENSMUSG00000073176(Zfp449),ENSMUSG00000078768(Zfp566),ENSMUSG00000047036(Zfp445),ENSMUSG00000034800(Zfp661),ENSMUSG00000071256(Zfp213),ENSMUSG00000051469(Zfp191)" " pupal stage , adult stage , larval stage | third instar " " adult head

, morphogenetic furrow

, eye-antennal disc

" " larval stage | third instar , larval stage | third instar && P-stage , embryonic stage , larval stage | third instar && P " " morphogenetic furrow

, secondary pigment cell

, brain | restricted

, eye-antennal disc

, cone cell

, morphogenetic furrow | vicinity of

, larval brain | restricted

, Bolwig's organ

, ocellus

, eye disc posterior to the morphogenetic furrow

, organism | restricted

, primary pigment cell

, photoreceptor cell

, tertiary pigment cell

" "visible,eye color defective,viable,lethal,heat sensitive,wild-type,recessive,good,fertile,locomotor behavior defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,auditory perception defective,neurophysiology defective,locomotor rhythm defective,behavior defective,reduced" "retina,ommatidium,eye photoreceptor cell,ocellus lens,eye,ocellus,rhabdomere,lamina,ocellus retinula cell,pigment cell,ocellus pigment granule,secondary pigment cell,tertiary pigment cell,embryonic/larval salivary gland,heat sensitive,retina & fascicle | somatic clone,photoreceptor cell R7,corpus cardiacum primordium,Bolwig organ primordium,Bolwig nerve,Bolwig organ,ring gland,embryonic/larval corpus cardiacum,photoreceptor cell,larval LN period neuron,serotonergic LP1 neuron,optic nerve,retina & axon,primary pigment cell,eyelet,photoreceptor cell & axon,eyelet photoreceptor,medulla,optic lobe,Pdf neuron,DN1 neuron" FBgn0002431 hyd hyperplastic discs http://flybase.net/reports/FBgn0002431.html FBgn0002317 protein_coding_gene "0043130=ubiquitin binding, 0008270=zinc ion binding, 0034450=ubiquitin-ubiquitin ligase activity, 0004842=ubiquitin-protein transferase activity, 0003723=RNA binding" "0030162=regulation of proteolysis, 0000209=protein polyubiquitination, 0045879=negative regulation of smoothened signaling pathway, 0007289=spermatid nucleus differentiation, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0007283=spermatogenesis, 0007446=imaginal disc growth, 0007444=imaginal disc development, 0008585=female gonad development, 0007281=germ cell development, 0042127=regulation of cell proliferation, 0007455=eye-antennal disc morphogenesis, 0007112=male meiosis cytokinesis, 0048749=compound eye development" "0005737=cytoplasm, 0005634=nucleus" "l(3)SG33, CG9484, l(3)c43, UBE 3A, l(3)85Ea, l(3)C43, c43, l(3)C43-3, l[[3]]c43, NP_524296.2, HYD, Hyd" "IPR002004=Polyadenylate-binding protein/Hyperplastic disc protein, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR024725=E3 ubiquitin ligase EDD, ubiquitin-associated domain, IPR015940=Ubiquitin-associated domain, IPR000569=HECT domain, IPR003126=Zinc finger, UBR-type" CG9484 16-Dec-15 2015_12 ENSDARG00000018192 WBGene00009460(F36A2.13) ENSMUSG00000037487(Ubr5) ENSG00000104517(UBR5) embryonic stage -- adult stage embryonic stage -- adult stage "lethal - all die before end of larval stage,some die during larval stage,viable,cytokinesis defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,heat sensitive,lethal,hyperplasia,male sterile,visible,somatic clone,increased cell death,female sterile,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die" "primary spermatocyte cyst,elongation stage spermatid,nucleus,meiotic primary spermatocyte,centrosome,spindle,spermatogonium,imaginal disc,wing disc,posterior compartment,somatic clone,eye disc,cell non-autonomous,eye,photoreceptor cell,ectopic,ovary,eye-antennal disc,heat sensitive,haltere disc,leg,wing,haltere,antenna,egg,germline clone,testis,mesothoracic tergum" DRSC28294 K -0.336435446 -1.28369594 0.468662914 -0.457280126 -2.094176548 -0.811346785 FBgn0010105 comm commissureless http://flybase.net/reports/FBgn0010105.html protein_coding_gene "0005515=protein binding, 0050699=WW domain binding" "0007399=nervous system development, 0006897=endocytosis, 0048813=dendrite morphogenesis, 0008038=neuron recognition, 0050773=regulation of dendrite development, 0070983=dendrite guidance, 0007411=axon guidance, 0002092=positive regulation of receptor internalization, 0031623=receptor internalization, 0016199=axon midline choice point recognition, 0007416=synapse assembly" "0031982=vesicle, 0005770=late endosome, 0030139=endocytic vesicle, 0005794=Golgi apparatus, 0005886=plasma membrane" "CG17943, Comm, Commissureless, Commisureless" CG17943 16-Dec-15 2015_12 " embryonic stage | stage 12-16 , embryonic stage | stage 10 , embryonic stage | stage 6-10 , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage >=10 " " ventral midline | restricted

, ganglion mother cell

,

segment polarity , midline glial cell

, neuroblast

, visceral mesoderm

, organism | pair rule

, epidermis

, embryonic central nervous system | presumptive | segmentally repeated pattern

" " embryonic stage | stage 10 , embryonic stage | stage 12-16 , embryonic stage , embryonic stage | stage 6-10 , embryonic stage | stage >=10 , embryonic stage | stage 5 " " neuroblast

, ventral midline | restricted

, ventral nerve cord commissure

,

segment polarity , midline glial cell

, neuron

, visceral mesoderm

, embryonic central nervous system | presumptive | segmentally repeated pattern

, organism | pair rule

, epidermis | longitudinal stripes

, ganglion mother cell

" "neuroanatomy defective,lethal,recessive,uncoordinated,lethal - all die before end of larval stage,some die during larval stage,cell autonomous,somatic clone,viable" "embryonic/larval neuron,ventral nerve cord commissure,commissure,longitudinal connective,mesothoracic dorsal triscolopidial chordotonal organ dch3,metathoracic dorsal triscolopidial chordotonal organ dch3,dMP2 neuron,embryonic/larval central nervous system,presumptive embryonic/larval central nervous system,midline crossing tract,ventral nerve cord commissure & larval brain | somatic clone,tritocerebral commissure,ventral anastomosis 0,ventral anastomosis 1,ventral anastomosis 2,ventral nerve cord,anterior commissure,posterior commissure,intersegmental nerve,midline glial cell,abdominal segmental nerve,axon | cell autonomous,neuroblast NB3-1,cell autonomous,neuroblast NB5-6,RP3 motor neuron,RP2 motor neuron,aCC neuron,V neuron,connective,ganglionic branch primordium,embryonic ventral nervous system,giant fiber neuron,antennal lobe glomerulus,antennal commissure,chordotonal organ & embryo & nerve terminal12.1,pCC neuron,motor neuron,dendriteeve.CQ2,longitudinal connective | embryonic stage,somatic clone,neuropil,dendrite | somatic cloneVGlut-OK371,longitudinal connective | embryonic stage 16,midline crossing tract | embryonic stage 16,dorsal branch | third instar larval stage" DRSC11336 I -0.559750369 1.500904487 0.856985588 0.671218101 -0.458750341 -1.099834365 FBgn0011739 wts warts http://flybase.net/reports/FBgn0011739.html FBgn0013549 protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0060253=negative regulation of glial cell proliferation, 0007067=mitotic nuclear division, 0045892=negative regulation of transcription, DNA-templated, 0048814=regulation of dendrite morphogenesis, 0046621=negative regulation of organ growth, 0043065=positive regulation of apoptotic process, 0001708=cell fate specification, 0045464=R8 cell fate specification, 0072089=stem cell proliferation, 0010212=response to ionizing radiation, 0042771=intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, 0060439=trachea morphogenesis, 0000082=G1/S transition of mitotic cell cycle, 0007298=border follicle cell migration, 0007446=imaginal disc growth, 0008285=negative regulation of cell proliferation, 0035329=hippo signaling, 0006468=protein phosphorylation, 0045570=regulation of imaginal disc growth, 0042127=regulation of cell proliferation, 0008360=regulation of cell shape, 0048749=compound eye development, 0007430=terminal branching, open tracheal system" "0005737=cytoplasm, 0005912=adherens junction" "miracle-gro, Dlats, warts/D-lats, LARGE tumor suppressor, Lats/Warts, lts, WTS/LATS, Warts, wart, Wts, LATS1, Large Tumor Suppressor, large tumor supressor, CG12072, lats, warts, l(3)100Aa, Warts/Lats, MENE (3R)-G, dmLATS, warts/large tumour suppressor, LATS, Wts/Lats, warts/lats, Lats, large tumor suppressor, wts/lats, Warts kinase" "IPR017441=Protein kinase, ATP binding site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR028741=Serine/threonine-protein kinase LATS1/ Warts, IPR028742=Serine/threonine-protein kinase LATS2, IPR000719=Protein kinase domain" CG12072 16-Dec-15 2015_12 ENSDARG00000003751(lats1) WBGene00007047(wts-1) "ENSMUSG00000040021(Lats1),ENSMUSG00000021959(Lats2)" "ENSG00000131023(LATS1),ENSG00000150457(LATS2)" " embryonic stage -- adult stage , adult stage | male , adult stage | female , embryonic stage | 0-4hr " "lethal,recessive,tumorigenic,neuroanatomy defective,visible,increased cell number,hyperplasia,partially lethal - majority die,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during third instar larval stage,somatic clone,male sterile,female sterile,decreased cell death,progressive,cell migration defective,stress response defective,mitotic cell cycle defective,size defective,neoplasia,partially,viable,body color defective,heat sensitive,increased cell growth" "eye disc,somatic clone,photoreceptor cell R8 of yellow ommatidium,photoreceptor cell R8 of pale ommatidium,supernumerary,rhabdomere R8,dorsal multidendritic neuron ddaC,eye,wing disc,retinal pigment cell,ectopic,ommatidium,pigment cell,head,wing,cell cycle | somatic clone,eye photoreceptor cell,progressive,border follicle cell,dorsal multidendritic neuron ddaC | somatic clone & dendritic tree,inter-ommatidial cell,intestinal stem cell,class IV dendritic arborizing neuron,dendrite,ommatidial precursor cluster,morphogenetic furrow,embryonic/larval central nervous system,pupa,imaginal disc,wing hair,posterior compartment,mesothoracic tergum,eye disc | third instar larval stage,embryonic/larval brain | third instar larval stage,embryonic/larval glial cell | third instar larval stage,terminal tracheal cell,embryonic/larval tracheal system,wing disc posterior compartment" FBgn0034970 yki yorkie http://flybase.net/reports/FBgn0034970.html protein_coding_gene "0005515=protein binding, 0008134=transcription factor binding, 0003713=transcription coactivator activity" "0072089=stem cell proliferation, 0001708=cell fate specification, 0002011=morphogenesis of an epithelial sheet, 0007298=border follicle cell migration, 0040008=regulation of growth, 0003007=heart morphogenesis, 0051568=histone H3-K4 methylation, 0045927=positive regulation of growth, 0060252=positive regulation of glial cell proliferation, 0035212=cell competition in a multicellular organism, 0008283=cell proliferation, 0007468=regulation of rhodopsin gene expression, 0043066=negative regulation of apoptotic process, 0045893=positive regulation of transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005770=late endosome, 0005634=nucleus, 0031410=cytoplasmic vesicle, 0005737=cytoplasm, 0005764=lysosome" "Yki, YKI, YAP, yap, CG4005, Yorkie" IPR001202=WW domain CG4005 16-Dec-15 2015_12 "ENSG00000137693(YAP1),ENSG00000018408(WWTR1)" "neuroanatomy defective,visible,size defective,increased cell number,somatic clone,mitotic cell cycle defective,hyperplasia,lethal,cell lethalcell lethal,increased cell size,cell shape defective,progressive,decreased cell death,increased cell growth,cell size defective,decreased cell number,cell migration defective,partially,lethal - all die before end of larval stage,some die during larval stage,tumorigenic,neoplasia,lethal - all die before end of pupal stage,some die during pupal stage" "larval outer optic anlage,larval inner optic anlage,eye,wing disc,posterior compartment,eye disc,intestinal stem cell,somatic clone,wing,eye photoreceptor cell,progressive,interommatidial bristle,supernumerary,pigment cell,eye-antennal disc,eye disc posterior to the morphogenetic furrow,epithelial cell,adult cuticle,adherens junctionen-e16E,cell autonomous,cell non-autonomous,interommatidial bristle | somatic cloneFRT.Act5C,border follicle cell,leg,haltere,follicle cell,eye disc | third instar larval stage,embryonic/larval brain | third instar larval stage,ventral nerve cord | third instar larval stage,embryonic/larval optic stalk | third instar larval stage,embryonic/larval glial cell | third instar larval stage,larval optic anlage,eye disc | larval stage,wing pouch,intestinal stem cell of posterior adult midgut epithelium,adult head,mesothoracic tergum,inter-ommatidial cell | pupal stage" DRSC28304 K 0.177098259 0.086929076 -0.360707193 0.149956402 0.866679245 2.651596454 FBgn0034659 CG4021 http://flybase.net/reports/FBgn0034659.html protein_coding_gene 0003723=RNA binding 0016607=nuclear speck cg4021 "IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG4021 16-Dec-15 2015_12 WBGene00022101(Y69A2AR.32) "male fertile,viable" FBgn0032507 CG9377 http://flybase.net/reports/FBgn0032507.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH166, c-SPH166" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG9377 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" viable FBgn0011225 jar jaguar http://flybase.net/reports/FBgn0011225.html "FBgn0004452, FBgn0010074" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0003779=actin binding, 0032027=myosin light chain binding, 0051015=actin filament binding, 0008017=microtubule binding, 0003774=motor activity, 0070856=myosin VI light chain binding, 0042623=ATPase activity, coupled, 0005516=calmodulin binding" "0007015=actin filament organization, 0008363=larval chitin-based cuticle development, 0032880=regulation of protein localization, 0007298=border follicle cell migration, 0045175=basal protein localization, 0045167=asymmetric protein localization involved in cell fate determination, 0055057=neuroblast division, 0007291=sperm individualization, 0061024=membrane organization, 0047497=mitochondrion transport along microtubule, 0007286=spermatid development, 0030589=pseudocleavage involved in syncytial blastoderm formation, 0055059=asymmetric neuroblast division, 0051647=nucleus localization, 0007051=spindle organization, 0006997=nucleus organization, 0030048=actin filament-based movement, 0007297=ovarian follicle cell migration, 0007560=imaginal disc morphogenesis, 0032956=regulation of actin cytoskeleton organization, 0030317=sperm motility, 0008104=protein localization, 0007391=dorsal closure, 0045921=positive regulation of exocytosis, 0040001=establishment of mitotic spindle localization, 0019749=cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte, 0030036=actin cytoskeleton organization, 0007283=spermatogenesis, 0048477=oogenesis, 0045217=cell-cell junction maintenance, 0032970=regulation of actin filament-based process, 0007552=metamorphosis, 0016333=morphogenesis of follicular epithelium" "0005875=microtubule associated complex, 0070864=sperm individualization complex, 0005938=cell cortex, 0045172=germline ring canal, 0031941=filamentous actin, 0031476=myosin VI complex, 0030139=endocytic vesicle, 0045178=basal part of cell, 0030426=growth cone, 0070865=investment cone, 0005737=cytoplasm, 0043234=protein complex, 0016461=unconventional myosin complex, 0016459=myosin complex" "95F myosin, myosin heavy chain, M6, 95F, Myosin VI, JAG, Myosin heavy chain at 95F, dMyoVI, Jar, Dm 95F, Dm95F, Myosin heavy chain, myosin VI, 95F unconventional myosin, unnamed, MHC95F, CG5695, MyoVI, Dro95F, ms(3)06746, 95F MHC, unconventional myosin VI, Jaguar, Mhc95F, jag, myosin 95F, myosin-VI, MYOVI, 95F Myosin, myosins VI, myo VI" "IPR001609=Myosin head, motor domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR004009=Myosin, N-terminal, SH3-like, IPR000048=IQ motif, EF-hand binding site" CG5695 16-Dec-15 2015_12 "ENSDARG00000044016(myo6a),ENSDARG00000042141(myo6b)" "WBGene00004969(spe-15),WBGene00002041(hum-8)" ENSXETG00000003610(myo6) ENSMUSG00000033577(Myo6) ENSG00000196586(MYO6) " embryonic stage , adult stage " " larval stage , adult stage , oogenesis stage | stage S9 , oogenesis stage | stage S9-10 , embryonic stage | late , oogenesis stage | stage S10 " " larval brain

, adult head

, adult thorax

, border follicle cell

, follicle cell

, gonad

, adult brain

" "partially lethal - majority die,male sterile,female fertile,embryonic/larval segmentation phenotype,male semi-sterile,recessive,viable,sterile,fertile,lethal,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,small body,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" "neuroblast & spindle, with jardsRNA.2,neuroblast & spindle, with jardsRNA.1,denticle belt,investment cone, with jar1/Df(3R)crb87-5,spermatid cyst,spermatozoon,spermatid,investment cone,investment conecrb87-5),seminal vesicle,investment conecrb87-5), with jarDel-N-Gtail.Hsp83.TAvicGFP,investment conecrb87-5), with jarmRRL.Hsp83.TAvicGFP,investment conecrb87-5), with jarmWKA.Hsp83.TAvicGFP,investment conecrb87-5), with jarmLWY.Hsp83.TAvicGFP,investment conecrb87-5), with jarHNPMD.Hsp83.TAvicGFP,dorsal closure embryo,embryonic leading edge cell,amnioserosa & actin filament,embryonic epidermis,lateral,posterior spiracle primordium,neuroblast & spindlemat.ë±Tub67C.THsimVP16,dorsal denticle,third instar larval cuticle,wing,leg,follicle cell,egg chamber,nurse cell & nucleusc532,follicle cell & nucleusc532,centripetally migrating follicle cell,border follicle cell,filopodium & border follicle cellslbo.2.6,trichogen cell,tormogen cell,male genitalia" FBgn0010583 dock dreadlocks http://flybase.net/reports/FBgn0010583.html FBgn0041141 protein_coding_gene "0005515=protein binding, 0005158=insulin receptor binding, 0050839=cell adhesion molecule binding, 0005070=SH3/SH2 adaptor activity, 0019901=protein kinase binding" "0008286=insulin receptor signaling pathway, 0046627=negative regulation of insulin receptor signaling pathway, 0007409=axonogenesis, 0007411=axon guidance, 0007520=myoblast fusion" 0005737=cytoplasm "CG3727, Dock, Nck, DOCK, doc, Dreadlocks, dck, l(2)04723, Dm0447" "IPR001452=SH3 domain, IPR017304=Cytoplasmic protein NCK, IPR000980=SH2 domain" CG3727 16-Dec-15 2015_12 "ENSDARG00000043361(zgc:92024),ENSDARG00000018206(nck2a)" WBGene00006410(nck-1) "ENSXETG00000022688(nck1),ENSXETG00000021669(nck2)" "ENSMUSG00000032475(Nck1),ENSMUSG00000066877(Nck2)" "ENSG00000158092(NCK1),ENSG00000071051(NCK2)" " embryonic stage | stage 14 , embryonic stage&&pupal stage&&adult stage " " embryonic brain

, ventral nerve cord

" larval stage | third instar " eye-antennal disc

, lamina neuropil

, neuron

, medulla neuropil

" "lethal,recessive,maternal effect,neuroanatomy defective,lethal - all die before end of pupal stage,uncoordinated,some die during pupal stage,somatic clone,cell non-autonomous,wild-type,visible,viable" "Bolwig nerve,longitudinal connective,embryonic/larval somatic muscle,RP3 neuron & synapse,maternal effect,photoreceptor cell & axon,ventral nerve cord commissure,VUM neuron,lamina neuropil,lamina anlage,medulla anlage,embryonic/larval optic lobe,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina,medulla,eye photoreceptor cell & growth cone,photoreceptor & axon,photoreceptor cell R7 & axon,photoreceptor & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,somatic clone,pCC neuron,MP1 neuron,neuron,photoreceptor cell,lamina plexus,embryonic/larval optic stalk,larval outer optic anlage,larval inner optic anlage,lobula,antennal lobe,antennal lobe & neuropil,antennal lobe glomerulus DM2,antennal lobe glomerulus DM3,cell non-autonomous,adult antennal nerve,antennal lobe glomerulus,ectopic,glial cell & antennal lobe,neuron & antennal lobe,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell & axon | somatic clone,RP3 motor neuron,neuromuscular junction | embryonic stage,eye" DRSC00812 I -0.020510833 -1.633869854 -0.184981699 -0.111917552 0.223467851 -0.688179154 FBgn0010303 hep hemipterous http://flybase.net/reports/FBgn0010303.html "FBgn0013490, FBgn0029076, FBgn0030446, FBgn0040188" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0008545=JUN kinase kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0004672=protein kinase activity, 0004708=MAP kinase kinase activity" "0045610=regulation of hemocyte differentiation, 0007391=dorsal closure, 0030707=ovarian follicle cell development, 0043507=positive regulation of JUN kinase activity, 0030381=chorion-containing eggshell pattern formation, 0007561=imaginal disc eversion, 0034769=basement membrane disassembly, 0046843=dorsal appendage formation, 0048666=neuron development, 0070328=triglyceride homeostasis, 0046847=filopodium assembly, 0035006=melanization defense response, 0046529=imaginal disc fusion, thorax closure, 0042060=wound healing, 0001736=establishment of planar polarity, 0071276=cellular response to cadmium ion, 0007298=border follicle cell migration, 0046528=imaginal disc fusion, 0045893=positive regulation of transcription, DNA-templated, 0048675=axon extension, 0007254=JNK cascade, 0043652=engulfment of apoptotic cell, 0046844=micropyle formation, 0010508=positive regulation of autophagy, 0007395=dorsal closure, spreading of leading edge cells, 0007411=axon guidance, 0071243=cellular response to arsenic-containing substance, 0009408=response to heat, 0006357=regulation of transcription from RNA polymerase II promoter, 0000165=MAPK cascade, 0046330=positive regulation of JNK cascade, 0051017=actin filament bundle assembly, 0030032=lamellipodium assembly, 0033500=carbohydrate homeostasis, 0006468=protein phosphorylation, 0008340=determination of adult lifespan" 0030424=axon "MAP2K7, JNKK, dJNKK, Hep/Mkk7, JNK-kinase, CG4353, DMKK7, JNK-Kinase, HEP, Mitogen-activated protein kinase kinase 7, MKK7, l(1)G0208, D-MKK7, MAPKK, dMKK7, DHEP/MKK7, hep/JNKK, Hep, DJNKK, hem, JNK kinase, hp, Hempiterous, Hemipterous, HEP/MKK7, l(1)G0107, l(1)7P1, CG2190, hrp, Mkk7" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG4353 16-Dec-15 2015_12 " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal,recessive,visible,chemical sensitive,lethal - all die before end of embryonic stage,viable,female,rescuable maternal effect,neuroanatomy defective,stress response defective,some die during embryonic stage,maternal effect,dominant,increased cell death,heat sensitive,lethal - all die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,male,wild-type,somatic clone,wound healing defective,mitotic cell cycle defective,small body,heat stress response defective,cell lethal,partially,cell shape defective,planar polarity defective,size defective,hyperplasia,temperature conditional,tumorigenic,partially lethal - majority live,cell death defective,chemical resistant,RU486 conditional,long lived,short lived" "adult thorax,chaeta,cuticle,dorsal,rescuable maternal effect,embryonic leading edge cell,embryonic dorsal epidermis,eye,wing,thorax,leg,mesothoracic tergum,wing disc,dorsal appendage,embryonic/first instar larval cuticle,embryonic epidermis,dorsal closure embryo,amnioserosa,embryonic leading edge cell & actin filament,adult head,adult mesothoracic segment,macrochaeta,maternal effect,axon & dorsal cluster neuron,maxillary palpus,female terminalia,germline clone,eye disc,imaginal disc,Kenyon cell,somatic clone,axon | somatic clone,eye-antennal disc,ventral thoracic disc,interommatidial bristle,pigment cell,micropyle,egg chamber,anterior,embryonic leading edge cell & filopodium,dorsal mesothoracic disc & cytoskeleton,cuticle & thorax,cuticle & abdomen,cephalopharyngeal skeleton,cuticle & thorax | germ-line clone,cuticle & abdomen | germ-line clone,peripodial epithelium & dorsal mesothoracic disc & prepupa,peripodial stalk & dorsal mesothoracic disc & prepupa,follicle cell,basement membrane | pupal stage,neuron,lamina,eye photoreceptor cell,embryonic maxillary segment,ommatidial precursor cluster,autolysosome | third instar larval stage,autophagic vacuole | third instar larval stage,embryonic/larval gut | third instar larval stage,embryonic/larval fat body | third instar larval stage,adult gut,temperature conditional,lamellocyte,melanotic mass,ventral adult lateral neuron & axonP2.4.Pdf,axon & dorsal cluster neuronato.3.6,wing vein,wing margin,wing vein L5,neuroblast | larval stage,scutellum,adult thorax & macrochaetapnr-MD237,ommatidium,genital disc,ventral furrow,heat sensitive" DRSC19839 K 0.835328143 1.228856735 0.385846125 0.591701195 -0.614963357 -1.538616774 FBgn0000163 baz bazooka http://flybase.net/reports/FBgn0000163.html "FBgn0040145, FBgn0042632" protein_coding_gene "0070300=phosphatidic acid binding, 0035091=phosphatidylinositol binding, 0005080=protein kinase C binding, 0005515=protein binding" "0008594=photoreceptor cell morphogenesis, 0008105=asymmetric protein localization, 0007309=oocyte axis specification, 0007314=oocyte anterior/posterior axis specification, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0007377=germ-band extension, 0007416=synapse assembly, 0002009=morphogenesis of an epithelium, 0007299=ovarian follicle cell-cell adhesion, 0007043=cell-cell junction assembly, 0090250=cell-cell adhesion involved in establishment of planar polarity, 0060446=branching involved in open tracheal system development, 0007294=germarium-derived oocyte fate determination, 0000281=mitotic cytokinesis, 0045175=basal protein localization, 0007163=establishment or maintenance of cell polarity, 0007298=border follicle cell migration, 0051490=negative regulation of filopodium assembly, 0030709=border follicle cell delamination, 0045196=establishment or maintenance of neuroblast polarity, 0040001=establishment of mitotic spindle localization, 0001738=morphogenesis of a polarized epithelium, 0045176=apical protein localization, 0035089=establishment of apical/basal cell polarity, 0008356=asymmetric cell division, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0055059=asymmetric neuroblast division, 2000040=regulation of planar cell polarity pathway involved in axis elongation, 0072002=Malpighian tubule development, 0090175=regulation of establishment of planar polarity, 0045186=zonula adherens assembly, 0016325=oocyte microtubule cytoskeleton organization, 0045167=asymmetric protein localization involved in cell fate determination" "0016327=apicolateral plasma membrane, 0035003=subapical complex, 0045179=apical cortex, 0005914=spot adherens junction, 0005913=cell-cell adherens junction, 0043296=apical junction complex, 0005915=zonula adherens, 0016324=apical plasma membrane, 0005912=adherens junction, 0045177=apical part of cell, 0005938=cell cortex" "D-Par3, CG5055, bazooka, Par3, par-3, Bazooka/Par-3, BAZ, Bazooka/Par3, Baz/Par3, Bazooka, dPar-3, Baz, Par-3, l(1)G0484, PAR3, Bazooka-Par3, Baz/Par-3, PAR-3, D-par3" "IPR001478=PDZ domain, IPR021922=Domain of unknown function DUF3534" CG5055 16-Dec-15 2015_12 ENSDARG00000010583(pard3) "ENSXETG00000006955(pard3),ENSXETG00000012407(Q5XGI8_XENTR)" "ENSMUSG00000025812(Pard3),ENSMUSG00000052062(Pard3b)" "ENSG00000116117(PARD3B),ENSG00000148498(PARD3)" embryonic stage " epithelial cell | apical

, neuroblast | apical

" " adult stage | female ,, embryonic stage " " germline cell

, stage S3 oocyte

anterior , neuroblast | apical

, stage S5 oocyte

anterior , epithelial cell | apical

" "female sterile,germline clone,lethal,recessive,increased cell death,viable,fertile,cell migration defective,planar polarity defective,cell polarity defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,cell shape defective,somatic clone,neurophysiology defective,neuroanatomy defective,partially lethal - majority die,visible" "photoreceptor cell & eye | somatic clone,embryonic neuroblast & spindle | germ-line clone,dorsal appendage,germline clone,maternal effect,oocyte nucleus,microtubule | germline clone,embryonic epidermis,embryonic/first instar larval cuticle,border follicle cell,embryonic abdominal segment,microtubule,embryo,terminal tracheal cell,somatic clone,follicle cell,oocyte,nurse cell,egg chamber,nurse cell fusome,epithelial cell,oocyte & centrosome | germ-line clone,oocyte & microtubule | germ-line clone,embryonic epidermis & spindle,embryonic ganglion mother cell,presumptive embryonic/larval central nervous system,embryonic leading edge cell,zonula adherens,adherens junction,neuroblast,dorsal,ventral,bouton,eye photoreceptor cell & eye disc & pupa | somatic clone,eye photoreceptor cell & eye disc & pupa | somatic clone | cell non-autonomous,eye,embryonic head,spot adherens junction,ommatidium,embryonic Malpighian tubule,late extended germ band embryo,presumptive embryonic/larval nervous system,embryonic/larval cuticle,ectopic,zonula adherens | somatic clone,germ band,egg,microtubuleunspecified,macrochaeta,trichogen cell,supernumerary,embryonic/larval neuromuscular junction,NMJ bouton" FBgn0020278 loco locomotion defects http://flybase.net/reports/FBgn0020278.html FBgn0038997 protein_coding_gene "0005057=receptor signaling protein activity, 0005096=GTPase activator activity, 0001965=G-protein alpha-subunit binding" "0006979=response to oxidative stress, 0003015=heart process, 0055059=asymmetric neuroblast division, 0008105=asymmetric protein localization, 0007303=cytoplasmic transport, nurse cell to oocyte, 0030866=cortical actin cytoskeleton organization, 0009408=response to heat, 0060857=establishment of glial blood-brain barrier, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0010001=glial cell differentiation, 0050832=defense response to fungus, 0007419=ventral cord development, 0042594=response to starvation, 0008277=regulation of G-protein coupled receptor protein signaling pathway, 0038032=termination of G-protein coupled receptor signaling pathway, 0019991=septate junction assembly" "0005886=plasma membrane, 0005737=cytoplasm, 0045179=apical cortex" "CG17229, CG5248, Loco, dLoco, Locomotion defect, Locomotion defects" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR024066=RGS, subdomain 1, IPR003109=GoLoco motif, IPR001478=PDZ domain, IPR029071=Ubiquitin-related domain, IPR016137=RGS domain, IPR003116=Raf-like Ras-binding, IPR006020=PTB/PI domain" CG5248 16-Dec-15 2015_12 "ENSDARG00000036774(rgs12),ENSDARG00000009610(wu:fc13d03)" ENSMUSG00000029101(Rgs12) ENSG00000159788(RGS12) " embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 16 " " glial cell

, embryonic peripheral nervous system

, lateral ectoderm | dorsal

, lateral ectoderm | restricted

, embryonic/larval tracheal system

" "immune response defective,viable,fertile,male semi-sterile,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,behavior defective,mitotic cell cycle defective,locomotor behavior defective,paralytic,visible" "hemocyte,testis,male accessory gland,anterior ejaculatory duct,axon | embryonic stage,embryonic/larval glial cell,longitudinal connective,lateral cord surface glia & nucleus,lateral cord surface glia & cell cortex & cortical cytoskeleton,lateral cord surface glia & septate junction,egg,ventral,dorsal appendage,neuroblast,spindle & mitotic domain 9,glial cell,subperineurial glial cell,yolk,embryonic foregut,embryonic/larval midgut primordium,embryonic/first instar larval cuticle,embryonic head,dorsal,tormogen cell" FBgn0011202 dia diaphanous http://flybase.net/reports/FBgn0011202.html FBgn0022100 protein_coding_gene "0003779=actin binding, 0005515=protein binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding, 0017048=Rho GTPase binding" "0051225=spindle assembly, 0031532=actin cytoskeleton reorganization, 0007110=meiosis I cytokinesis, 0045448=mitotic cell cycle, embryonic, 0030589=pseudocleavage involved in syncytial blastoderm formation, 0097320=membrane tubulation, 0045010=actin nucleation, 0030838=positive regulation of actin filament polymerization, 0022008=neurogenesis, 0007015=actin filament organization, 0000915=actomyosin contractile ring assembly, 0035011=melanotic encapsulation of foreign target, 0009306=protein secretion, 0007349=cellularization, 0007283=spermatogenesis, 0007111=meiosis II cytokinesis, 0000281=mitotic cytokinesis, 0003383=apical constriction, 0007279=pole cell formation, 0007605=sensory perception of sound, 0051489=regulation of filopodium assembly, 0090303=positive regulation of wound healing, 0008104=protein localization, 0032507=maintenance of protein location in cell, 0007424=open tracheal system development, 0016476=regulation of embryonic cell shape" "0005737=cytoplasm, 0043234=protein complex, 0012506=vesicle membrane, 0035230=cytoneme, 0005912=adherens junction, 0016324=apical plasma membrane, 0005938=cell cortex, 0005884=actin filament, 0032154=cleavage furrow, 0045177=apical part of cell" "DIA, 38E.16, ms(2)04138, Diaphanous, Dias, l(2)k07135, Dia, CG1768" "IPR027658=Formin, protein diaphanous, IPR010465=DRF autoregulatory, IPR014767=Diaphanous autoregulatory (DAD) domain, IPR010472=Formin, FH3 domain, IPR014768=Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR010473=Formin, GTPase-binding domain, IPR015425=Formin, FH2 domain, IPR016024=Armadillo-type fold" CG1768 16-Dec-15 2015_12 ENSDARG00000009519(zgc:100947) YIL159W(BNR1) WBGene00000872(cyk-1) ENSXETG00000018132(DIAPH2) "ENSMUSG00000034480(Diap2),ENSMUSG00000022021(Diap3),ENSMUSG00000024456(Diap1)" "ENSG00000147202(DIAPH2),ENSG00000139734(DIAPH3)" " adult stage | female , adult stage | male " "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,non-rescuable maternal effect,cytokinesis defective,auditory perception defective,dominant,neurophysiology defective,somatic clone,wound healing defective,viable,fertile,male sterile,female sterile,wild-type,meiotic cell cycle defective,male,mitotic cell cycle defective,maternal effect,cell shape defective,neuroanatomy defective,partially lethal - majority die,visible,immune response defective" "contractile ring & meiotic cell cycle | male,spindle & meiotic cell cycle | male,imaginal disc,larval central nervous system & neuroblast,actin filament & embryonic/larval tracheal systembtl.PS,filopodium | ectopicen-e16E,epidermal cell,embryonic leading edge cell,furrow canal,germline clone,cycle 11 embryo,cytoskeleton | embryonic stage | germline clone,nucleus | embryonic stage | germline clone,pole cell,gastrula embryo,dorsal closure embryo,embryonic head,denticle belt,embryonic/first instar larval cuticle,actin filament | embryonic stage | germline clone,microtubule | embryonic stage | germline clone,centrosome | embryonic stage | germline clone,pole bud,blastoderm embryo,ventral furrow,non-rescuable maternal effect,actin filament & embryonic/larval tracheal system,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,morphogenetic furrow,somatic clone,epithelium,follicle cell,egg chamber,filopodium,lamellipodium,tormogen cell,bract,organism | dorsal closure stage | maternal effect,amnioserosa,maternal effect,filopodiumen-e16E,lamellipodiumen-e16E,testis,spermatocyte,spermatid,Nebenkern,cyst cell,spermatid & nucleus | supernumerary,spermatid & nucleus | supernumeraryTW84),spindle & meiotic cell cycle | maleTW84),contractile ring & meiotic cell cycle | maleTW84),eye,ectoderm,border follicle cell,tracheal fusion cell,embryonic/larval dorsal trunk,embryonic epidermis,organism | dorsal closure stagec381,epithelial cell,presumptive embryonic/larval central nervous system,commissure,connective,air sac primordium | third instar larval stage,S2 cell-line & spindle microtubule,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,wing" DRSC03519 K 0.67371844 -0.02539349 0.114864457 -0.298054878 -1.62014316 0.014326413 FBgn0011592 fra frazzled http://flybase.net/reports/FBgn0011592.html protein_coding_gene 0005042=netrin receptor activity "0016199=axon midline choice point recognition, 0008347=glial cell migration, 0070983=dendrite guidance, 0008045=motor neuron axon guidance, 0007411=axon guidance, 0050773=regulation of dendrite development, 0048813=dendrite morphogenesis, 0007432=salivary gland boundary specification" "0016021=integral component of membrane, 0043025=neuronal cell body, 0098595=perivitelline space, 0030424=axon, 0030425=dendrite, 0005886=plasma membrane" "Fra, CG8581, deleted in colorectal cancer, CT24981, DCC, Netrin-receptor, frazzled, Deleted in Colorectal Carcinoma, DCC/Frazzled, Frazzled" "IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR010560=Neogenin, C-terminal, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set" CG8581 16-Dec-15 2015_12 "ENSDARG00000018556,ENSDARG00000008937(neo1)" WBGene00006776(unc-40) ENSXETG00000005195(NEO1) "ENSMUSG00000060534(Dcc),ENSMUSG00000032340(Neo1)" "ENSG00000187323(DCC),ENSG00000067141(NEO1)" embryonic stage " embryonic central nervous system

, embryonic/larval digestive system

" " embryonic stage | late , embryonic stage | stage >=13 , embryonic stage | stage >=12 , embryonic stage | stage 13-17 " " intersegmental nerve

, epidermis

, longitudinal connective

, ventral nerve cord commissure

, segmental nerve

, embryonic/larval midgut

, neuron

, motor nerve

" "behavior defective,neuroanatomy defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,viable,female sterile,female fertile" "ventral nerve cord commissure | embryonic stage,EW neuron,EG neuron,presumptive embryonic/larval central nervous system,ventral nerve cord commissure,pCC neuron & axon,intersegmental nerve,longitudinal connective,SP1 neuron,commissure,anterior commissure,posterior commissure,presumptive embryonic salivary gland,dMP2 neuron,fascicle,Bolwig nerve,motor neuron,dendrite,interface glial cell,class IV dendritic arborizing neuron,commissure & embryo & axon,RP3 motor neuron,lamina,optic lobe,somatic clone,photoreceptor cell R8 stalk,neuropil,dendrite | somatic clone,dendrite | somatic cloneVGlut-OK371" FBgn0004657 mys myospheroid http://flybase.net/reports/FBgn0004657.html "FBgn0001448, FBgn0001811, FBgn0002992, FBgn0020759, FBgn0025177, FBgn0027260, FBgn0028333, FBgn0029991" protein_coding_gene "0050839=cell adhesion molecule binding, 0046982=protein heterodimerization activity, 1990430=extracellular matrix protein binding, 0004872=receptor activity, 0005515=protein binding" "0007517=muscle organ development, 0007160=cell-matrix adhesion, 0008360=regulation of cell shape, 0045214=sarcomere organization, 0030336=negative regulation of cell migration, 0035160=maintenance of epithelial integrity, open tracheal system, 0007377=germ-band extension, 0021551=central nervous system morphogenesis, 0008340=determination of adult lifespan, 0007508=larval heart development, 0034446=substrate adhesion-dependent cell spreading, 0007427=epithelial cell migration, open tracheal system, 0007015=actin filament organization, 0007608=sensory perception of smell, 0007411=axon guidance, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0033627=cell adhesion mediated by integrin, 0035099=hemocyte migration, 0007298=border follicle cell migration, 0035001=dorsal trunk growth, open tracheal system, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0051492=regulation of stress fiber assembly, 0030718=germ-line stem cell maintenance, 0007391=dorsal closure, 0006930=substrate-dependent cell migration, cell extension, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0007431=salivary gland development, 0007494=midgut development, 0003344=pericardium morphogenesis, 0016340=calcium-dependent cell-matrix adhesion, 0048803=imaginal disc-derived male genitalia morphogenesis, 0007417=central nervous system development, 0016203=muscle attachment, 0007155=cell adhesion, 0016477=cell migration, 0007426=tracheal outgrowth, open tracheal system, 0031589=cell-substrate adhesion" "0031252=cell leading edge, 0005887=integral component of plasma membrane, 0005927=muscle tendon junction, 0008305=integrin complex, 0016328=lateral plasma membrane, 0009925=basal plasma membrane, 0005886=plasma membrane, 0043034=costamere, 0005925=focal adhesion" "lethal myospheroid, non-jumper-42, beta1, integrin betaPS subunit, CT40473, PS integrin beta subunit, beta-PS, beta[[mys]]-integrin, PS, l(1)mys, Integrin betaPS, EM28, beta-Integrin, beta-Int, PSbeta, olfactory C, beta PS integrin, betaPS.*integrin, l(1)7Dn, olfC, beta-PS Integrin, beta[[PS]] integrin subunit, beta-PS1 integrin, betaPS1, l(1)968, betaInt, beta integrin, Myospheroid, l(1)EM28, betaPS, beta-int, olfactory-C, beta-PS integrin, Integrin betaPS subunit, integrin-betaPS, betaIntegrin, CG1560, beta[[mys]], integrin betaPS, BetaPS, Myospheriod, beta[[PS]], l(1)G0233, MAb6G11, beta1 integrin, Integrin-betaPS, l(1)93p, bPS, lethal(1)myospheroid, beta[[PS]] integrin, PS-beta-integrin, integrinbeta, betaPS-integrin, PS[[beta]], beta-PS-Integrin, betaps-integrin, l(1)7Db, PSbeta-integrin, myospheriod, beta[[PS]]-integrin, ItgbPS, BetaPS integrin, betaPS-Integrin, BetaPS-Int, b[[PS]], integrin beta[[PS]], Mys, integrin beta[[PS]] subunit, lethal(1)93 pupal, l(1)DA551, beta[[P]]S, nj42, betaPS integrin, betaPS Int, betamys, myo-spheroid, beta-integrin, l(1)G0281, integrin PSbeta" "IPR002035=von Willebrand factor, type A, IPR015812=Integrin beta subunit, IPR000742=EGF-like domain, IPR012896=Integrin beta subunit, tail, IPR014836=Integrin beta subunit, cytoplasmic domain, IPR013111=EGF-like domain, extracellular, IPR002369=Integrin beta subunit, N-terminal, IPR016201=Plexin-like fold" CG1560 16-Dec-15 2015_12 "ENSDARG00000071863(itgb1a),ENSDARG00000001822,ENSDARG00000053255,ENSDARG00000053232(itgb1b.1),ENSDARG00000022689(itgb1b.2),ENSDARG00000045070(itgb3b)" WBGene00003930(pat-3) ENSXETG00000019163(ITGB3) "ENSMUSG00000025809(Itgb1),ENSMUSG00000000290(Itgb2),ENSMUSG00000020689(Itgb3)" "ENSG00000150093(ITGB1),ENSG00000160255(ITGB2),ENSG00000056345,ENSG00000139626(ITGB7)" " embryonic stage , embryonic stage | stage 15-16 , larval stage | third instar " " embryonic/larval hindgut

, muscle attachment site

, tendon cell | restricted & muscle fiber | vicinity of muscle attachment site

, embryonic/larval pharynx

, embryonic/larval midgut

" "visible,somatic clone,viable,male,lethal,lethal - all die before end of first instar larval stage,smell perception defective,recessive,partially lethal - majority die,wild-type,heat sensitive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,cell shape defective,partially,reduced,germline clone,rescuable maternal effect,flightless,lethal - all die before end of pupal stage,some die during pupal stage" ",haltere,amnioserosa,extended germ band embryo,visceral mesoderm,somatic muscle,central nervous system,muscle fiber,embryo | dorsal closure stage,germ band,muscle tendon junction,wing,neuromuscular junction,male genitalia,dorsal closure embryo,embryonic epidermis,bouton,egg chamber,chorion,follicle cell,eye,stomodeum,tendon cell,embryonic somatic muscle,germ layer,midgut primordium,embryonic/larval somatic muscle,embryonic/larval midgut,embryonic/first instar larval cuticle,cardial valve,Z disc,anterior midgut primordium,salivary gland common duct primordium,posterior midgut primordium,presumptive embryonic salivary gland,circular visceral muscle primordium,muscle attachment site,embryonic/larval visceral branch,gastric caecum,embryonic/larval proventriculus,abdominal segment border muscle,abdominal lateral longitudinal muscle,abdominal ventral longitudinal muscle,ventral nerve cord,embryonic dorsal epidermis,pericardial cell,dorsal superficial trachea,embryonic/larval salivary gland,leg,tergite,adult cuticle,ommatidium,rhabdomere,terminal tracheal cell,wing blade,interfollicle cell,female germline cyst,dorsal trunk primordium,stress fiber,filamentous actin,fascicle,embryonic heart cardioblast,vertical lobe of adult mushroom body,stage S14 oocyte,retina,pigment cell,anterior crossvein,crossvein,dorsal wing blade,ventral wing blade,hub cell,genitalia,dorsal medial muscle,posterior spiracle primordium,ë±,F11,male germline stem cell,dorsal multidendritic neuron ddaC |,dorsal multidendritic neuron ddaC,cardial cell | adult stage,border follicle cell" FBgn0011824 CG4038 http://flybase.net/reports/FBgn0011824.html protein_coding_gene 0030515=snoRNA binding "0009267=cellular response to starvation, 0031118=rRNA pseudouridine synthesis, 0022008=neurogenesis" "0005730=nucleolus, 0005654=nucleoplasm, 0031429=box H/ACA snoRNP complex, 0005732=small nucleolar ribonucleoprotein complex" "dGAR1, Pen101, GCR 101, CG4038-PA, GCR101, anon-Pen101, GCR101 SnRNP" "IPR021154=H/ACA ribonucleoprotein complex, subunit Gar1, IPR009000=Translation protein, beta-barrel domain, IPR007504=H/ACA ribonucleoprotein complex, subunit Gar1/Naf1" CG4038 16-Dec-15 2015_12 "ENSDARG00000068150,ENSDARG00000068155" YHR089C(GAR1) WBGene00022046(Y66H1A.4) ENSXETG00000024114(nola1) ENSMUSG00000028010(Gar1) ENSG00000109534(GAR1) "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000140 asp abnormal spindle http://flybase.net/reports/FBgn0000140.html "FBgn0014939, FBgn0062123" protein_coding_gene "0008017=microtubule binding, 0032027=myosin light chain binding" "0051383=kinetochore organization, 0007282=cystoblast division, 0030706=germarium-derived oocyte differentiation, 0007051=spindle organization, 0030954=astral microtubule nucleation, 0007017=microtubule-based process, 0048854=brain morphogenesis, 0051297=centrosome organization, 0048477=oogenesis, 0000132=establishment of mitotic spindle orientation, 0051295=establishment of meiotic spindle localization, 0007097=nuclear migration, 0000226=microtubule cytoskeleton organization, 0051642=centrosome localization, 0030723=ovarian fusome organization, 0007052=mitotic spindle organization, 0048132=female germ-line stem cell asymmetric division, 0030037=actin filament reorganization involved in cell cycle" "0005813=centrosome, 0005875=microtubule associated complex, 0005815=microtubule organizing center, 0000922=spindle pole" "Asp, CG6875, ASP, anon-WO0118547.279, unnamed, Abnormal spindle protein, abnormal spindle protein, Dm Asp, Abnormal spindle, abnormal spindles, anon-96Aa, Abnormal spindles" "IPR029955=Abnormal spindle-like microcephaly-associated protein, IPR027401=Myosin-like IQ motif-containing domain, IPR001715=Calponin homology domain, IPR000048=IQ motif, EF-hand binding site" CG6875 16-Dec-15 2015_12 ENSDARG00000071442(aspm) WBGene00008107(aspm-1) ENSXETG00000009955(ASPM) ENSG00000066279(ASPM) embryonic stage && larval stage && adult stage "partially lethal - majority die,recessive,viable,female sterile,lethal,wild-type,maternal effect,mitotic cell cycle defective,male sterile,visible,meiotic cell cycle defective,male,cytokinesis defective,female semi-sterile,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,female,semi-sterile,cell adhesion defective,neuroanatomy defective,increased cell death,somatic clone" "eye,macrochaeta,germline cyst,embryonic/larval brain,spindle | maternal effect,wing,spermatocyte & spindle,spermatocyte & aster,ovariole,egg chamber,oocyte nucleus,spermatocyte & spindleHdë_1),centrosome,microtubule organizing center,larval brain & neuroblast & centrosome,larval brain & neuroblast & mitotic cell cycle,larval brain & neuroblast & aster,larval brain & neuroblast & spindle,Nebenkern,onion stage spermatid & nucleus,aster | male,spermatocyte & centrosome,meiotic telophase II & spindle,meiotic telophase II & contractile ring,fusome,imaginal disc,spermatid,spindle,embryonic/larval neuroblast,adult head,germarium & spindle,germarium & microtubule,nurse cell ring canal,germarium,actomyosin contractile ring | male,spermatocyte ring canal,oocyte,spermatocyte,spermatocyte & microtubule organizing center,spermatocyte & microtubule,spindle | ectopic,anaphase & condensed nuclear chromosome,mitotic cell cycle,optic lobe,optic lobe forming neuroblast,lamina,mitotic spindle | third instar larval stage,somatic clone | third instar larval stage,mitotic spindle | somatic clone | third instar larval stageë±Tub84B.PC" FBgn0034246 Dcr-2 Dicer-2 http://flybase.net/reports/FBgn0034246.html protein_coding_gene "0004386=helicase activity, 0003677=DNA binding, 0016887=ATPase activity, 0004525=ribonuclease III activity, 0005524=ATP binding, 0035197=siRNA binding, 0003725=double-stranded RNA binding" "0002230=positive regulation of defense response to virus by host, 0030422=production of siRNA involved in RNA interference, 0030423=targeting of mRNA for destruction involved in RNA interference, 0098586=cellular response to virus, 0007626=locomotory behavior, 0033227=dsRNA transport, 0031054=pre-miRNA processing, 0009047=dosage compensation by hyperactivation of X chromosome, 0016246=RNA interference, 0035087=siRNA loading onto RISC involved in RNA interference, 0051607=defense response to virus, 0070868=heterochromatin organization involved in chromatin silencing, 0006342=chromatin silencing, 0006379=mRNA cleavage, 0009597=detection of virus" "0016442=RISC complex, 0005634=nucleus, 0005737=cytoplasm" "cg6493, dcr, dicer-2, Dcr2, Dicer2, DICER-2, dic2, DCR-2, dicer2, dicer, CG6493, DICER, DICER2, Dicer 2, Dcr, Dicer, DCR2, dcr-2, dcr2" "IPR014720=Double-stranded RNA-binding domain, IPR001650=Helicase, C-terminal, IPR005034=Dicer dimerisation domain, IPR006935=Helicase/UvrB, N-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR000999=Ribonuclease III domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003100=PAZ domain" CG6493 16-Dec-15 2015_12 "locomotor behavior defective,sleep defective,RU486 conditional,touch sensitivity defective,neuroanatomy defective,viable,lethal,locomotor rhythm defective,short lived,male,heat sensitive,visible,flightless,some die during pupal stage,flight defective,chemical resistant,partially lethal,neurophysiology defective,lethal - all die during pupal stage,partially lethal - majority die,learning defective,courtship behavior defective,grooming behavior defective,female,mating behavior defective,planar polarity defective,progressive,gravitaxis defective,partially lethal - majority live,male sterile,meiotic cell cycle defective,wild-type,immune response defective,recessive,stress response defective,suppressor of variegation,dominant,conditional,partially" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3, mriGD7508,sensory dendrite | larval stage, with Nmdar1GD2808, 1003.3,sensory dendrite | larval stage, with Nmdar2GD3192, 1003.3,sensory dendrite | larval stage1003.3, rpkGD3621,sensory dendrite | larval stage1003.3, naGD1172,sensory dendrite | larval stage1003.3, nompCKK105819,wing,wing margin bristle,H zoneMef2.PR, Zasp52KK101276,indirect flight muscle,myofibrilMef2.PR, Zasp52KK101276,Z discMef2.PR, Zasp52KK101276,M bandMef2.PR, Zasp52KK101276,H zoneMef2.PR, Zasp52dsRNA.ex16.UAS,myofibrilMef2.PR, Zasp66KK112973,Z discMef2.PR, Zasp66KK112973,M bandMef2.PR, Zasp66KK112973,posterior compartment,heat sensitive,1st posterior cell,anterior crossvein,mitochondrion, with Aats-serdsRNA.UAS.WIZ, ,mitochondrial matrix, with Aats-serdsRNA.UAS.WIZ, ,mitochondrial crista, with Aats-serdsRNA.UAS.WIZ, ,ommatidium,rhabdomere, with Cep89KK103260, GMR.PF,mitochondrion, with Cep89KK103260, GMR.PF,eye photoreceptor cell,wing vein,wing hair,embryonic/larval neuromuscular junction | larval stage,embryonic/larval neuromuscular junction | third instar larval stage,presynaptic active zoneelav.PU, simjKK107461,myofibril, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,striated muscle thin filament, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,striated muscle myosin thick filament, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,sarcomere, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,M band, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,Z disc, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,Nebenkern,primary spermatocyte,onion stage spermatid,apterous-expressing neuron of the lateral cluster of the thorax,septate junction, with McrKK104742, ap-md544" FBgn0002576 lz lozenge http://flybase.net/reports/FBgn0002576.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0044212=transcription regulatory region DNA binding, 0005524=ATP binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0006952=defense response, 0048477=oogenesis, 0035165=embryonic crystal cell differentiation, 0035170=lymph gland crystal cell differentiation, 0045467=R7 cell development, 0046672=positive regulation of compound eye retinal cell programmed cell death, 0048749=compound eye development, 0035162=embryonic hemopoiesis, 0035168=larval lymph gland hemocyte differentiation, 0042675=compound eye cone cell differentiation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0030097=hemopoiesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0001709=cell fate determination, 0007486=imaginal disc-derived female genitalia development, 0016360=sensory organ precursor cell fate determination, 0035314=scab formation, 0042688=crystal cell differentiation, 0042981=regulation of apoptotic process, 0042060=wound healing, 0007165=signal transduction, 0035163=embryonic hemocyte differentiation, 0030154=cell differentiation, 0048592=eye morphogenesis, 0045165=cell fate commitment, 0035211=spermathecum morphogenesis, 0007469=antennal development" 0005634=nucleus "CG1689, fs(1)M69, Lz, fs(1)A1569, amx, spe, Lozenge, spectacled" "IPR000040=Acute myeloid leukemia 1 protein (AML1)/Runt, IPR012346=p53/RUNT-type transcription factor, DNA-binding domain, IPR008967=p53-like transcription factor, DNA-binding, IPR013524=Runt domain" CG1689 16-Dec-15 2015_12 WBGene00004393(rnt-1) ENSXETG00000001029(RUNX3) "ENSMUSG00000022952(Runx1),ENSMUSG00000039153(Runx2),ENSMUSG00000070691(Runx3)" "ENSG00000020633(RUNX3),ENSG00000159216(RUNX1)" "increased cell death,visible,recessive,semidominant,female sterile,eye color defective,viable,fertile,dominant,male fertile,female fertile,heat sensitive,lethal,female,wild-type,smell perception defective,increased cell number,decreased cell death,cold sensitive,male sterile,poor,partially,wound healing defective,neuroanatomy defective,male,male semi-sterile,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "third segment of antenna,ommatidium,eye,lens,interommatidial bristle,pigment cell,cone cell,optic lobe,photoreceptor cell R7,spermathecum,female accessory gland,unguis,ovary,sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,maxillary palp sensillum basiconicum,eye disc,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,posterior,lamina,retina,sensillum coeloconicum of antennal segment 3,cell body rind of lamina,prothoracic unguis,mesothoracic unguis,metathoracic unguis,photoreceptor cell R2,photoreceptor cell R5,ectopic,tarsal segment,spermathecal duct,supernumerary,heat sensitive,sensillum basiconicum,crystal cell,antennal sense organ,precursor,secondary pigment cell,tertiary pigment cell,temperature conditional,antenna,maxillary palpus,embryonic/larval optic stalk,sensillum trichodeum,medulla,lobula,lobula plate,pulvillus,cell non-autonomous,somatic clone,pigment granule | cell non-autonomous | somatic clone,ommatidial precursor cluster,antennal lobe glomerulus DL2,antennal lobe glomerulus V,antennal lobe glomerulus VL2,antennal lobe glomerulus,eye-antennal disc,sensillum coeloconicum & antennal segment 3,fascicle & antennal segment 3,antennal commissure,adult antennal nerve,hemocyte,plasmatocyte,dorsal closure embryo" DRSC18790 IE 0.46296584 -2.834996802 -0.281992306 -1.696294956 -0.793218918 0.713147481 FBgn0259752 ms(3)Z2203 http://flybase.net/reports/FBgn0259752.html gene "0007283=spermatogenesis, 0051276=chromosome organization" "162-039, ms(3)162-39" 16-Dec-15 2015_12 "male sterile,viable,meiotic cell cycle defective,male" "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,chromosome & primary spermatocyte,spindle" FBgn0261875 Z2-0557 http://flybase.net/reports/FBgn0261875.html gene 0030431=sleep 16-Dec-15 2015_12 behavior defective FBgn0015574 ë±-Est6 ë±-Esterase-6 http://flybase.net/reports/FBgn0015574.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "fragment G, E, F, fragment E, unnamed, fragment F, DmalphaE6, aE6, Esterase-6, alpha-Est6, alphaE6, G, CG1108" "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold" CG1108 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" viable FBgn0036641 Smn survival motor neuron http://flybase.net/reports/FBgn0036641.html FBgn0025499 protein_coding_gene "0051393=alpha-actinin binding, 0003723=RNA binding" "0030240=skeletal muscle thin filament assembly, 0000387=spliceosomal snRNP assembly, 0035154=terminal cell fate specification, open tracheal system, 0022618=ribonucleoprotein complex assembly, 0007528=neuromuscular junction development" "0031594=neuromuscular junction, 0030018=Z disc, 0005737=cytoplasm, 0005634=nucleus, 0071254=cytoplasmic U snRNP body, 0015030=Cajal body, 0031674=I band" "CG16725, l(3)73Ao, DmSMN, survival of motor neurons, dSMN, smn, SMN, Survival of Motor Neurons, Survival Motor Neuron" "IPR002999=Tudor domain, IPR010304=Survival motor neuron" CG16725 16-Dec-15 2015_12 ENSDARG00000018494(smn1) "ENSXETG00000018189(),ENSXETG00000004912()" ENSMUSG00000021645(Smn1) "ENSG00000205571(SMN2),ENSG00000172062(SMN1)" "small body,locomotor behavior defective,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,neuroanatomy defective,developmental rate defective,some die during third instar larval stage,partially lethal - majority die,some die during pupal stage,flight defective,jumping defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die during pupal stage,neurophysiology defective,size defective,locomotor rhythm defective,lethal - all die before end of pupal stage,lethal,visible,germline clone,non-rescuable maternal effect,female sterile,uncoordinated,increased cell death,flightless,viable,fertile" "NMJ bouton,NMJ bouton | third instar larval stage,embryonic/larval neuromuscular junction,embryonic/larval somatic muscle,wing vein L4,wing vein L5,posterior crossvein,dorsal medial muscle,indirect flight muscle,indirect flight muscle motor neuron,striated muscle thin filament,embryonic/larval trachea,tracheal lumen" FBgn0005278 Sam-S S-adenosylmethionine Synthetase http://flybase.net/reports/FBgn0005278.html "FBgn0011287, FBgn0031218" protein_coding_gene "0005524=ATP binding, 0004478=methionine adenosyltransferase activity" "0022416=chaeta development, 0035220=wing disc development, 0006730=one-carbon metabolic process, 0006556=S-adenosylmethionine biosynthetic process" "S-adenosylmethionine synthetase, METK, m(2)21ab, S-Adenosylmethionine synthetase, CG2674, M(2)21A-B, M(2)21AB, Su(z)5, Minute (2) 21AB, SamS, Sam-S, Methionine adenosyl transferase" "IPR022636=S-adenosylmethionine synthetase superfamily, IPR022631=S-adenosylmethionine synthetase, conserved site, IPR002133=S-adenosylmethionine synthetase, IPR022629=S-adenosylmethionine synthetase, central domain, IPR022630=S-adenosylmethionine synthetase, C-terminal, IPR022628=S-adenosylmethionine synthetase, N-terminal" CG2674 16-Dec-15 2015_12 "ENSDARG00000039605(mat1a),ENSDARG00000037121(zgc:110847)" "YDR502C(SAM2),YLR180W(SAM1)" "WBGene00015540(sams-4),WBGene00015538(sams-3),WBGene00006416(sams-5),WBGene00013652(sams-2),WBGene00008205(sams-1)" "ENSXETG00000003530(MAT1A),ENSXETG00000001263(mat2a)" "ENSMUSG00000053907(Mat2a),ENSMUSG00000037798(Mat1a)" "ENSG00000168906(MAT2A),ENSG00000151224(MAT1A)" " embryonic stage -- adult stage , adult stage | female " ovary

"visible,partially lethal - majority die,some die during pupal stage,suppressor of variegation,dominant,lethal,recessive,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage" "trichogen cell,mesothoracic tergum,macrochaeta,germline clone,scutellar bristle,tergite,male genitalia,eye" DRSC00758 E 0.630570168 1.319451612 1.036792331 -4.220513748 -0.485952449 0.404377586 FBgn0040857 CG11366 http://flybase.net/reports/FBgn0040857.html protein_coding_gene 16-Dec-15 2015_12 FBgn0085438 CG34409 http://flybase.net/reports/FBgn0085438.html "FBgn0037738, FBgn0051411, FBgn0051412" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG12949, CG31412, SP12, CG31411, c-SP12" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG34409 16-Dec-15 2015_12 "viable,visible" trichogen cell FBgn0004509 Fur1 Furin 1 http://flybase.net/reports/FBgn0004509.html "FBgn0010236, FBgn0024579, FBgn0039334" protein_coding_gene 0004252=serine-type endopeptidase activity "0001941=postsynaptic membrane organization, 0006508=proteolysis, 0097688=glutamate receptor clustering, 0016485=protein processing, 0008039=synaptic target recognition, 0097090=presynaptic membrane organization" "0005886=plasma membrane, 0030173=integral component of Golgi membrane, 0016021=integral component of membrane, 0005795=Golgi stack" "Dfur1, Klip1, l(3)rL205, fur-1, fur[1], Furl, furin, CG10772, Dfurin1, fur1, dKLIP-1, dFurin 1, dFur1, furin1, Furin1, Furin-like protease, Furin" "IPR009020=Proteinase inhibitor, propeptide, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR022398=Peptidase S8, subtilisin, His-active site, IPR006212=Furin-like repeat, IPR023827=Peptidase S8, subtilisin, Asp-active site, IPR008979=Galactose-binding domain-like, IPR015500=Peptidase S8, subtilisin-related, IPR023828=Peptidase S8, subtilisin, Ser-active site, IPR002884=Proprotein convertase, P, IPR000209=Peptidase S8/S53 domain" CG10772 16-Dec-15 2015_12 ENSDARG00000002600(pcsk1) WBGene00002232(kpc-1) ENSXETG00000015462(FURIN) ENSG00000175426(PCSK1) " embryonic stage , adult stage , adult stage && oogenesis stage , embryonic stage | stage 16 , adult stage | female " " embryonic/larval hindgut

, embryonic central nervous system | restricted

, labral segment

, adult brain cortex

, anal pad

, nurse cell

, central nervous system | restricted

, oocyte

, oenocyte

, embryonic/larval pharynx

, follicle cell

, embryonic/larval posterior spiracle

, central nervous system

, fat body

, subesophageal ganglion

, embryonic/larval trachea

, oviduct

, tracheal pit

, antenno-maxillary complex

" "viable,fertile,lethal,recessive,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0062530 l(3)88EFb lethal (3) 88EFb http://flybase.net/reports/FBgn0062530.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0038341 AdamTS-A ADAM metallopeptidase with thrombospondin type 1 motif A http://flybase.net/reports/FBgn0038341.html FBgn0038340 protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" "0006508=proteolysis, 0007427=epithelial cell migration, open tracheal system, 0007436=larval salivary gland morphogenesis, 0008078=mesodermal cell migration, 0007280=pole cell migration" 0005578=proteinaceous extracellular matrix "CG6107, CG14869, AdamTS-A, CT19033" "IPR001590=Peptidase M12B, ADAM/reprolysin, IPR013273=Peptidase M12B, ADAM-TS, IPR024079=Metallopeptidase, catalytic domain, IPR012314=Peptidase M12B, GON-ADAMTSs, IPR002870=Peptidase M12B, propeptide, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR010294=ADAM-TS Spacer 1" CG14869 16-Dec-15 2015_12 WBGene00001650(gon-1) "ENSMUSG00000030022,ENSMUSG00000022449(Adamts20)" "ENSG00000163638(ADAMTS9),ENSG00000173157(ADAMTS20)" "cell migration defective,viable" "germline cell,longitudinal visceral muscle primordium,embryonic/larval visceral branch,embryonic/larval salivary gland" DRSC14992 K -0.380311723 0.363173196 0.497270764 0.318829286 1.827039026 0.50338303 FBgn0028345 l(1)G0213 lethal (1) G0213 http://flybase.net/reports/FBgn0028345.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259356 EP-773 http://flybase.net/reports/FBgn0259356.html gene 16-Dec-15 2015_12 visible "wing vein,wing hair,wing margin" FBgn0038739 CG4686 http://flybase.net/reports/FBgn0038739.html FBgn0062514 protein_coding_gene BcDNA:AT09463 IPR006696=Protein of unknown function DUF423 CG4686 16-Dec-15 2015_12 WBGene00013720(Y106G6H.8) ENSMUSG00000070394(1810027O10Rik) ENSG00000205544(C17orf61) "viable,fertile" FBgn0002624 M(3)96CF Minute (3) 96CF http://flybase.net/reports/FBgn0002624.html gene "M[[j]], M(3)j, M(3)Sp" 16-Dec-15 2015_12 "Minute,dominant,visible,female sterile,male fertile,developmental rate defective" "macrochaeta,wing,wing vein,adult abdomen,posterior dorsocentral bristle,posterior scutellar bristle,femur & macrochaeta" FBgn0034230 CG4853 http://flybase.net/reports/FBgn0034230.html protein_coding_gene 0005088=Ras guanyl-nucleotide exchange factor activity "0043547=positive regulation of GTPase activity, 0046579=positive regulation of Ras protein signal transduction, 0016319=mushroom body development" "IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR023578=Ras guanine nucleotide exchange factor domain, IPR030710=Ras-GEF domain-containing family member 1B, IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR019804=Ras guanine-nucleotide exchange factor, conserved site" CG4853 16-Dec-15 2015_12 WBGene00019902(R05G6.10) "neuroanatomy defective,viable" "antennal lobe,adult mushroom body" FBgn0011481 Ssdp Sequence-specific single-stranded DNA-binding protein http://flybase.net/reports/FBgn0011481.html FBgn0038580 protein_coding_gene 0003697=single-stranded DNA binding "0035220=wing disc development, 0006355=regulation of transcription, DNA-templated, 0048812=neuron projection morphogenesis" 0005634=nucleus "ssdp, l(3)neo48, CG7187, Sequence-specific single-strand DNA-binding protein" "IPR006594=LIS1 homology motif, IPR008116=Sequence-specific single-strand DNA-binding protein" CG7187 16-Dec-15 2015_12 "ENSDARG00000056483(ssbp4),ENSDARG00000015991(LOC798086),ENSDARG00000058237(ssbp3),ENSDARG00000057395(si:ch211-130m23.3),ENSDARG00000030155(zgc:63791)" WBGene00012990(Y48C3A.8) "ENSXETG00000022940(),ENSXETG00000019994(ssbp3),ENSXETG00000027809(SSBP2)" "ENSMUSG00000061887(Ssbp3),ENSMUSG00000003992(Ssbp2),ENSMUSG00000070003(Ssbp4)" "ENSG00000157216(SSBP3),ENSG00000145687(SSBP2),ENSG00000130511(SSBP4)" "lethal,recessive,partially lethal - majority die,partially,germline clone,visible,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "anterior scutellar bristle,supernumerary,posterior scutellar bristle,wing,mesothoracic tergum,macrochaeta,somatic clone,dorsal,cell non-autonomous,wing margin bristle,ectopic,adult cuticle,scutellar bristle" FBgn0005129 l(1)w lethal (1) w http://flybase.net/reports/FBgn0005129.html gene 16-Dec-15 2015_12 "lethal,female,recessive" FBgn0002723 Met Methoprene-tolerant http://flybase.net/reports/FBgn0002723.html protein_coding_gene "0005500=juvenile hormone binding, 0042803=protein homodimerization activity, 0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0003700=sequence-specific DNA binding transcription factor activity" "0050793=regulation of developmental process, 0043069=negative regulation of programmed cell death, 0006355=regulation of transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "met, Rst(1)JH, MET, DmMet, methoprene tolerant, Methoprene-tolerant protein, bHLHe59, Met, methoprene-tolerant, Mett, Methoprene-tolerant, juvenile hormone resistance, Resistance (1) Juvenile H, CG1705, Met/Met1, Resistance to Juvenile Hormone" "IPR001610=PAC motif, IPR000014=PAS domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG1705 16-Dec-15 2015_12 " adult stage | female , embryonic stage , embryonic stage -- adult stage " "chemical resistant,visible,partially lethal - majority die,some die during larval stage,lethal - all die before end of larval stage,lethal,viable,dominant,recessive,wild-type,chemical sensitive,female fertile,reduced,lethal - all die before end of pupal stage,partially,some die during pupal stage,female semi-sterile,semidominant" "eye,embryonic/larval fat body | wandering third instar larval stage,ommatidium,abdominal sternite bristle,male genitalia,stage S8 oocyte,stage S9 oocyte,stage S10 oocyte,stage S11 oocyte,stage S12 oocyte,stage S13 oocyte,stage S14 oocyte,ovary,optic lobe,photoreceptor cell R7,photoreceptor cell R8,lobula,lobula plate,tarsal segment 1 & joint,tarsal segment 2 & joint,leg sensillum" FBgn0086424 l(3)CHh lethal (3) CHh http://flybase.net/reports/FBgn0086424.html gene complementation group 10 16-Dec-15 2015_12 "lethal,recessive" FBgn0262319 mir-1000 mir-1000 stem loop http://flybase.net/reports/FBgn0262319.html miRNA_gene "1903295=negative regulation of glutamate secretion, neurotransmission" "CR43026, dme-mir-1000, miR-1000" CR43026 16-Dec-15 2015_12 "viable,visible,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing vein,wing vein L5,wing margin" FBgn0030241 feo fascetto http://flybase.net/reports/FBgn0030241.html FBgn0001477 protein_coding_gene 0008017=microtubule binding "0022008=neurogenesis, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0043148=mitotic spindle stabilization, 0000916=actomyosin contractile ring contraction, 0051533=positive regulation of NFAT protein import into nucleus, 0000281=mitotic cytokinesis, 0051298=centrosome duplication" "0005737=cytoplasm, 0005813=centrosome, 0051233=spindle midzone" "EA86, Feo, l(1)9Fe, Fascetto, lethal(1)9Fe, CG11207, Q54, l(1)BP1, PRC1" "IPR007145=Microtubule-associated protein, MAP65/Ase1/PRC1" CG11207 16-Dec-15 2015_12 "ENSDARG00000005993(prc1b),ENSDARG00000010511(prc1a),ENSDARG00000005098(zgc:86764)" YOR058C(ASE1) "ENSXETG00000015449(PRC1),ENSXETG00000018081()" ENSMUSG00000038943(Prc1) ENSG00000198901(PRC1) "lethal,recessive,cytokinesis defective,cell lethal,germline clone,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,cold sensitive,neuroanatomy defective" "posterior supraalar bristle,cold sensitive,mitotic telophase & spindle,mitotic telophase & contractile ring,spermatocyte,testis,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,epithelium,female germline cyst" FBgn0036746 Crtc CREB-regulated transcription coactivator http://flybase.net/reports/FBgn0036746.html protein_coding_gene 0008140=cAMP response element binding protein binding "0051289=protein homotetramerization, 0042594=response to starvation, 0032793=positive regulation of CREB transcription factor activity, 0006979=response to oxidative stress" "0005634=nucleus, 0005737=cytoplasm" "CG6064, CRTC, cg6064, ORE-12, dTORC, TORC1, TORC" "IPR024785=Transducer of regulated CREB activity, C-terminal, IPR024786=CREB-regulated transcription coactivator, IPR024783=Transducer of regulated CREB activity, N-terminal" CG6064 16-Dec-15 2015_12 "ENSDARG00000053872,ENSDARG00000052114(crtc3)" WBGene00021237(Y20F4.2) "ENSXETG00000011199(CRTC1),ENSXETG00000001294(BC088575.1)" "ENSMUSG00000027936(Crtc2),ENSMUSG00000003575(Crtc1),ENSMUSG00000030527(Crtc3)" "ENSG00000160741(CRTC2),ENSG00000140577(CRTC3),ENSG00000105662(CRTC1)" "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,short lived,stress response defective" "eye,ommatidium,interommatidial bristle" FBgn0005592 btl breathless http://flybase.net/reports/FBgn0005592.html "FBgn0000436, FBgn0000654, FBgn0004412, FBgn0004420, FBgn0004600, FBgn0019834, FBgn0022794, FBgn0052134, FBgn0063611" protein_coding_gene "0005524=ATP binding, 0005007=fibroblast growth factor-activated receptor activity, 0004713=protein tyrosine kinase activity" "0001763=morphogenesis of a branching structure, 0007498=mesoderm development, 0040018=positive regulation of multicellular organism growth, 0007417=central nervous system development, 0035215=genital disc development, 0030517=negative regulation of axon extension, 0007426=tracheal outgrowth, open tracheal system, 0060438=trachea development, 0006468=protein phosphorylation, 0007428=primary branching, open tracheal system, 0046847=filopodium assembly, 0060439=trachea morphogenesis, 0008543=fibroblast growth factor receptor signaling pathway, 0007424=open tracheal system development, 0007427=epithelial cell migration, open tracheal system, 0007430=terminal branching, open tracheal system, 0035153=epithelial cell type specification, open tracheal system, 0007298=border follicle cell migration, 0007517=muscle organ development, 0000187=activation of MAPK activity, 0008347=glial cell migration, 0007429=secondary branching, open tracheal system, 0007492=endoderm development, 0007435=salivary gland morphogenesis, 0060446=branching involved in open tracheal system development" "0035230=cytoneme, 0005886=plasma membrane" "Dfr-2, dev, FGF receptor, D-FGFR, l(3)00208, HD-311, CG6714, CT20816, Fgf-r, fgf-r, DFR2, Tk2, Btl, dtk2, dFGFR, 0844/01, Fibroblast growth factor receptor 1, FGFR1, FGFR, lambdatop, no terminal cell clones-L, devenir, CG32134, fibrobast growth factor receptor, Dtk2, BTL/FGFR2, Breathless, fibroblast growth factor receptor, DmHD-311, Fibroblast-growth-factor-receptor, DFGF-R1" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR008266=Tyrosine-protein kinase, active site, IPR013151=Immunoglobulin, IPR013098=Immunoglobulin I-set, IPR017441=Protein kinase, ATP binding site, IPR007110=Immunoglobulin-like domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG32134 16-Dec-15 2015_12 "ENSDARG00000004782(fgfr3),ENSDARG00000069105(fgfr4),ENSDARG00000011027(fgfr1a),ENSDARG00000011190,ENSDARG00000058115" WBGene00001184(egl-15) "ENSXETG00000002396(),ENSXETG00000016775(fgfr1),ENSXETG00000015592(FGFR2),ENSXETG00000007231(fgfr4)" "ENSMUSG00000030849(Fgfr2),ENSMUSG00000031565(Fgfr1),ENSMUSG00000054252(Fgfr3),ENSMUSG00000005320(Fgfr4)" "ENSG00000066468(FGFR2),ENSG00000077782(FGFR1),ENSG00000160867(FGFR4),ENSG00000068078(FGFR3)" " embryonic stage | stage 12 , embryonic stage | stage >=10 , embryonic stage | stage 6-8 , embryonic stage | stage >=8 , embryonic stage , embryonic stage | stage >=13 , embryonic stage | stage >5 , embryonic stage | stage 11 " " midline glial cell

, VUM neuron

, embryonic/larval tracheal system

, anterior midgut proper primordium

, tracheal pit

, tracheal primordium

, posterior midgut proper primordium

, ventral midline

, embryonic/larval salivary gland

, tracheal pit

{ v btl6-81&Dgr;1 } " embryonic stage " tracheal pit

, embryonic/larval trachea

, ventral midline

" "lethal,viable,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,visible,somatic clone,neuroanatomy defective,cell migration defective" "terminal tracheal cell,somatic clone,embryonic/larval dorsal branch & terminal tracheal cell | somatic clone,embryonic/larval tracheal system,embryonic/larval dorsal branch,embryonic/larval trachea,presumptive embryonic/larval tracheal system,ganglionic branch primordium,visceral branch primordium,tracheal branch primordium,dorsal trunk primordium,embryonic tracheal system & filopodium,tracheal tip cell & filopodium,dorsal branch primordium,dorsal air sac primordium,embryonic/larval dorsal trunk,air sac tracheoblast of dorsal air sac primordium,air sac tracheoblast of dorsal mesothoracic disc & filopodium,lateral trunk anterior branch,embryonic/larval muscle system,tracheal primordium,tracheal pit,eye,actin cytoskeleton | pupal stage | somatic clone,midline glial cell,embryonic/larval ganglionic branch,lateral G branch,coiled tracheole,pupal tracheal system,axon & dorsal cluster neuron & adult brainato.3.6,pupal abdominal trachea,filopodium,axon & dorsal cluster neuronato.3.6,chorion,embryo,denticle belt,ectopic,tracheal lumen,subretinal glial cell,somatic clone | third instar larval stage" DRSC11331 I 1.660711391 0.980699045 0.688982689 0.895770908 -0.502397429 -0.591115356 FBgn0028500 Rich RIC1 homolog http://flybase.net/reports/FBgn0028500.html protein_coding_gene "0017137=Rab GTPase binding, 0017112=Rab guanyl-nucleotide exchange factor activity" "0060078=regulation of postsynaptic membrane potential, 0043547=positive regulation of GTPase activity, 0035418=protein localization to synapse, 0045467=R7 cell development, 0050808=synapse organization, 0032483=regulation of Rab protein signal transduction, 0007411=axon guidance" "0016023=cytoplasmic membrane-bounded vesicle, 0005794=Golgi apparatus" "ric1 homologue, CG9063, ric1 homolog, 3L6, BcDNAGH03694, rich, BcDNA:GH03694" "IPR009771=Ribosome control protein 1, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG9063 16-Dec-15 2015_12 WBGene00011071(R06F6.8) ENSXETG00000000582(KIAA1432) ENSMUSG00000038658(C030046E11Rik) ENSG00000107036(KIAA1432) "lethal,recessive,neurophysiology defective,somatic clone,neuroanatomy defective,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "optic cartridge,somatic clone,photoreceptor cell R7,cell autonomous,trichogen cell,mesothoracic tergum" FBgn0003475 spir spire http://flybase.net/reports/FBgn0003475.html "FBgn0029122, FBgn0032854, FBgn0040997" protein_coding_gene "0003779=actin binding, 0005515=protein binding, 0008017=microtubule binding" "0016192=vesicle-mediated transport, 0045451=pole plasm oskar mRNA localization, 0045010=actin nucleation, 0007015=actin filament organization, 0007316=pole plasm RNA localization, 0030717=karyosome formation, 0051493=regulation of cytoskeleton organization, 0030036=actin cytoskeleton organization, 0048477=oogenesis, 0007315=pole plasm assembly, 0051639=actin filament network formation, 0030029=actin filament-based process, 0007304=chorion-containing eggshell formation" "0005737=cytoplasm, 0005938=cell cortex" "CG10076, spire, CG18621, p150-Spir, 38C.37, 38C.34, Spir, NP2788, p150Spir, l(2)08327, Spire" "IPR011011=Zinc finger, FYVE/PHD-type, IPR011019=KIND domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR003124=WH2 domain, IPR029901=Protein Spire" CG10076 16-Dec-15 2015_12 "ENSDARG00000035868(zgc:153436),ENSDARG00000038445,ENSDARG00000003084(zgc:103506)" ENSXETG00000019863(SPIRE2) "ENSMUSG00000010154(Spire2),ENSMUSG00000024533(Spire1)" "ENSG00000134278(SPIRE1),ENSG00000204991(SPIRE2)" "oxidative stress response defective,female sterile,viable,grandchildless,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,lethal,maternal effect,female semi-sterile" "embryo,germline clone,maternal effect,posterior,stage S8 oocyte & microtubule,egg chamber,chorion | maternal effect,pole cell,embryonic abdomen,egg,follicle cell,dorsal appendage,blastoderm embryo,karyosome,oocyte nucleus,oocyte,filamentous actin | oogenesis stage S9,actin filamentExel6046),actin filament, with Df(2L)Exel6046, nos.UTR.THsimVP16" FBgn0002622 RpS3 Ribosomal protein S3 http://flybase.net/reports/FBgn0002622.html FBgn0010267 protein_coding_gene "0003906=DNA-(apurinic or apyrimidinic site) lyase activity, 0008534=oxidized purine nucleobase lesion DNA N-glycosylase activity, 0003723=RNA binding, 0003735=structural constituent of ribosome" "0006412=translation, 0043524=negative regulation of neuron apoptotic process, 0006974=cellular response to DNA damage stimulus, 0006281=DNA repair, 0007067=mitotic nuclear division" "0005634=nucleus, 0005737=cytoplasm, 0005840=ribosome, 0016363=nuclear matrix, 0022627=cytosolic small ribosomal subunit, 0005875=microtubule associated complex" "dS3, M(3)B, Minute, M(3)95A, rpS3, Mw, Rp S3, ribosomal protein S3, M(3)B2, Rps3, chr3R:19185518..19185701, 6779, M, M(3)Fla, M[[w]], rps3, M(3)124, X72921, RPS3, CG6779, M95A, RS3, S3, M(3R)w, M(3)w, rps3 gene, DmRpS3, Minute(3)95A" "IPR004044=K Homology domain, type 2, IPR018280=Ribosomal protein S3, conserved site, IPR005703=Ribosomal protein S3, eukaryotic/archaeal, IPR009019=K homology domain, prokaryotic type, IPR001351=Ribosomal protein S3, C-terminal, IPR015946=K homology domain-like, alpha/beta, IPR004087=K Homology domain" CG6779 16-Dec-15 2015_12 ENSDARG00000046119(rps3) YNL178W(RPS3) WBGene00004472(rps-3) ENSXETG00000010729(rps3) ENSMUSG00000030744(Rps3) ENSG00000149273(RPS3) "lethal,recessive,visible,dominant,female fertile,reduced,Minute,size defective,viable,male sterile,female sterile,cell lethal,developmental rate defective,fertile,small body" "scutellar bristle,macrochaeta,adult heart,eye-antennal disc,wing disc,male genitalia,testis,primary spermatocyte cyst,germarium,egg chamber,ovariole,eye" DRSC16838 EK -1.457786632 0.186830685 -0.64497703 -3.473035645 0.796679579 3.822449427 FBgn0003255 rk rickets http://flybase.net/reports/FBgn0003255.html protein_coding_gene "0004930=G-protein coupled receptor activity, 0016500=protein-hormone receptor activity, 0008188=neuropeptide receptor activity" "0007564=regulation of chitin-based cuticle tanning, 0007186=G-protein coupled receptor signaling pathway, 0001837=epithelial to mesenchymal transition, 0007218=neuropeptide signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "Rickets, Glycoprotein hormone receptor II, BG:DS00180.13, CG8930, leucine-rich repeat-containing G protein-coupled receptor 2, rk/CG8930, CT25644, LGR2, DLGR2, glycoprotein-hormone-receptor-II, DLGR-2, glycoprotein hormone receptor II" "IPR001611=Leucine-rich repeat, IPR017452=GPCR, rhodopsin-like, 7TM, IPR002131=Glycoprotein hormone receptor family, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR003591=Leucine-rich repeat, typical subtype" CG8930 16-Dec-15 2015_12 "ENSDARG00000018648,ENSDARG00000060542(LOC558825)" "ENSMUSG00000050199(Lgr4),ENSMUSG00000020140(Lgr5),ENSMUSG00000042793(Lgr6)" "ENSG00000139292(LGR5),ENSG00000133067(LGR6),ENSG00000205213(LGR4)" " embryonic stage , pupal stage " "lethal - all die before end of embryonic stage,recessive,visible,viable,fertile,some die during embryonic stage,decreased cell death,partially lethal - majority die,mating defective,male,reduced,behavior defective,developmental rate defective,small body,body color defective,lethal,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,locomotor behavior defective" "wing,leg,tarsal segment,adult cuticle,neurosecretory neuron,metathoracic leg,macrochaeta,posterior scutellar bristle,heat sensitive,abdomen,haltere,pupal cuticle,metathoracic tarsal segment,mesothoracic tergum" FBgn0002552 lin lines http://flybase.net/reports/FBgn0002552.html FBgn0033346 protein_coding_gene "0008293=torso signaling pathway, 0007440=foregut morphogenesis, 0007362=terminal region determination, 0035277=spiracle morphogenesis, open tracheal system, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035220=wing disc development, 0008544=epidermis development, 0009880=embryonic pattern specification, 0048617=embryonic foregut morphogenesis, 0048619=embryonic hindgut morphogenesis, 0007442=hindgut morphogenesis, 0009946=proximal/distal axis specification" "0005737=cytoplasm, 0005634=nucleus" "CG11770, Lin" "IPR029415=Protein Lines, C-terminal, IPR024875=Protein Lines" CG11770 16-Dec-15 2015_12 embryonic stage " inclusive hindgut primordium

, embryonic epidermis

, mesoderm

, stomodeum

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,lethal,visible,somatic clone,increased cell death,partially lethal - majority die,some die during pupal stage" "denticle row 1,denticle row 2,denticle row 3,denticle row 4,denticle belt,denticle,ectopic,dorsal denticle,embryonic hindgut,dorsal thick hair,dorsal fine hair,embryonic/larval posterior spiracle,embryonic/larval hindgut,embryonic Malpighian tubule,embryonic/larval somatic muscle,dorsal,abdominal segment 8,embryonic foregut,keyhole structure,embryonic dorsal epidermis,embryonic large intestine,embryonic proventriculus,embryonic epidermis,embryonic head,embryonic segment,anterior,embryonic abdominal segment 8,anal plate,primordium of embryonic/larval spiracle,disc epithelium proper & dorsal mesothoracic disc | somatic clone,wing hinge primordium,somatic clone,heart primordium,photoreceptor cell,eye,denticle belt & abdominal segment 8,mouthpart,anal pad,hindgut proper primordium,prothoracic tarsal segment,cell autonomous,antenna,peripodial epithelium & dorsal mesothoracic discptc-559.1,eye disc,peripodial epithelium & dorsal mesothoracic discUbx-lac1-Gal4,adult thorax,peripodial epithelium & dorsal mesothoracic disc | somatic clone,antennal disc,head capsule,prescutum,sex comb,arista,basal cylinder,third segment of antenna,mesothoracic tergum" FBgn0005613 Sox15 Sox box protein 15 http://flybase.net/reports/FBgn0005613.html "FBgn0024287, FBgn0040750" protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0043066=negative regulation of apoptotic process, 0045892=negative regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0035220=wing disc development, 0008285=negative regulation of cell proliferation, 0022416=chaeta development" 0005634=nucleus "CG13945, Dsox-15, SoxF, CG8404, SOX50E, Sox F, SOX15, SoxE, Sox50E, DSox-15, SOXF" IPR009071=High mobility group box domain CG8404 16-Dec-15 2015_12 "ENSXETG00000005746(),ENSXETG00000006348(SOX10),ENSXETG00000022348()" ENSMUSG00000024176(Sox8) "visible,locomotor behavior defective,neurophysiology defective,partially lethal - majority die,recessive,size defective,increased cell number,increased cell death,short lived,some die during pupal stage" "wing hinge,joint,mechanosensory chaeta,tormogen cell,eo dendrite,wing sclerite,alula,wing hinge primordium,wing blade,trichogen cell" DRSC07555 K 0.204688004 -0.765390591 -0.915025291 -1.224853626 1.594020322 -0.073472382 FBgn0051525 CG31525 http://flybase.net/reports/FBgn0051525.html FBan0031525 protein_coding_gene CG31525 16-Dec-15 2015_12 viable FBgn0069309 X-31-10 X-31-10 http://flybase.net/reports/FBgn0069309.html gene 0007399=nervous system development 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,neurogenic phenotype,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" FBgn0039132 AP-1ìÄ "Adaptor Protein complex 1, ìÄ subunit" http://flybase.net/reports/FBgn0039132.html FBgn0043469 protein_coding_gene "0030276=clathrin binding, 0008565=protein transporter activity" "0007269=neurotransmitter secretion, 0048749=compound eye development, 0046907=intracellular transport, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0042051=compound eye photoreceptor development, 0016183=synaptic vesicle coating, 0006901=vesicle coating, 0007411=axon guidance" "0008021=synaptic vesicle, 0030121=AP-1 adaptor complex, 0030135=coated vesicle" "AP-1sigma1, AP-1sigma, cg5864, CG5864, AP1sigma1, aps1, AP-1[sigma], sigma1" "IPR011012=Longin-like domain, IPR000804=Clathrin adaptor complex, small chain, IPR022775=AP complex, mu/sigma subunit, IPR016635=Adaptor protein complex, sigma subunit" CG5864 16-Dec-15 2015_12 "ENSDARG00000058504(ap1s2),ENSDARG00000056803(ap1s1)" YLR170C(APS1) WBGene00000159(aps-1) ENSXETG00000022468(ap1s2) "ENSMUSG00000031367(Ap1s2),ENSMUSG00000004849(Ap1s1)" "ENSG00000182287(AP1S2),ENSG00000106367(AP1S1)" "viable,visible,body color defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum,eye,ommatidium,photoreceptor cell R7,photoreceptor cell R8" FBgn0005012 dipp-3 defective in phototaxis plasticity 3 http://flybase.net/reports/FBgn0005012.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0084370 C20 C20 http://flybase.net/reports/FBgn0084370.html gene 16-Dec-15 2015_12 eye color defective pigment cell FBgn0020388 Gcn5 Gcn5 ortholog http://flybase.net/reports/FBgn0020388.html FBgn0046345 protein_coding_gene "0010485=H4 histone acetyltransferase activity, 0004402=histone acetyltransferase activity, 0010484=H3 histone acetyltransferase activity, 0003682=chromatin binding" "0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0043966=histone H3 acetylation, 0016573=histone acetylation, 0043967=histone H4 acetylation, 0007517=muscle organ development, 0007412=axon target recognition, 0006338=chromatin remodeling" "0005634=nucleus, 0005703=polytene chromosome puff, 0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0005700=polytene chromosome, 0000124=SAGA complex" "Ada4, GCN5, Pcaf, PCAF, CG4107, dGcn5, dGCN5, gcn5, dmGCN5, KAT, dKAT2, dGCN5 HAT, anon-WO0172774.89, dPCAF, Gcn5/Pcaf, dmHAG401, Gcn5/PCAF, dGcn5i, p/CAF, P/CAF, Gcn5, KAT2" "IPR001487=Bromodomain, IPR009464=PCAF, N-terminal, IPR018359=Bromodomain, conserved site, IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain, IPR016376=Histone acetylase PCAF" CG4107 16-Dec-15 2015_12 ENSDARG00000062634(kat2b) WBGene00021636(pcaf-1) "ENSXETG00000002303(KAT2A),ENSXETG00000014008(KAT2B)" "ENSMUSG00000000708(Kat2b),ENSMUSG00000053208(Gm5109),ENSMUSG00000020918(Kat2a)" "ENSG00000108773(KAT2A),ENSG00000114166(KAT2B)" embryonic stage -- adult stage "lethal,partially lethal - majority die,some die during pharate adult stage,viable,visible,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of larval stage,some die during larval stage" "metathoracic leg,wing,eye,ommatidium,adult cuticle & adult abdomen,cuticle & abdomen & pharate adult,femur,trichogen cell,wing disc,posterior compartment,wing vein,tarsal segment,wing margin,cuticle & abdomen & pharate adultesg-NP5153,ovary,stage S5 oocyte,stage S6 oocyte,prepupa,polytene chromosome puff | wandering third instar larval stage,imaginal disc,eye photoreceptor cell,intestinal stem cell" DRSC26932 K -0.073088845 0.437495193 -1.089664747 0.105412039 1.710966674 1.922924509 FBgn0000674 flo fiber loop http://flybase.net/reports/FBgn0000674.html gene flo[N115] 16-Dec-15 2015_12 axon & optic lobe FBgn0020840 l(2)CA61 lethal (2) CA61 http://flybase.net/reports/FBgn0020840.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003346 RanGAP Ran GTPase activating protein http://flybase.net/reports/FBgn0003346.html protein_coding_gene 0005096=GTPase activator activity "0022008=neurogenesis, 0043547=positive regulation of GTPase activity, 0045132=meiotic chromosome segregation, 0006611=protein export from nucleus, 0006913=nucleocytoplasmic transport" "0048471=perinuclear region of cytoplasm, 0005737=cytoplasm" "rangap, CG9999, SD, Ran, Ran GTPase Activating Protein, Sd, RanGAP, CT28175, RanGap1, Segregation Distorter, ranGAP, RanGap, Scl, dRanGAP, ranGap, Sd-RanGAP, Sd-RanGap, RGP1_DROME, Segregation distorter" "IPR009109=Ran-GTPase activating protein 1, C-terminal, IPR027038=Ran GTPase-activating protein" CG9999 16-Dec-15 2015_12 "ENSDARG00000056059(rangap1),ENSDARG00000041317(zgc:154097)" YMR235C(RNA1) ENSXETG00000006331(RANGAP1) ENSMUSG00000022391(Rangap1) ENSG00000100401(RANGAP1) " adult stage , pupal stage " " adult stage | male , embryonic stage , adult stage , larval stage " " testis

, larval salivary gland

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,meiotic cell cycle defective,dominant" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,spermatid,embryonic/larval salivary gland" DRSC22003 K 0.748988278 0.123681811 0.059167357 1.145165847 1.516206825 0.165668162 FBgn0015600 toc toucan http://flybase.net/reports/FBgn0015600.html "FBgn0010486, FBgn0063149" protein_coding_gene 0019901=protein kinase binding "0007476=imaginal disc-derived wing morphogenesis, 0030707=ovarian follicle cell development, 0000070=mitotic sister chromatid segregation, 0007052=mitotic spindle organization, 0035186=syncytial blastoderm mitotic cell cycle" "0031965=nuclear membrane, 0000922=spindle pole, 0030496=midbody, 0005938=cell cortex, 0005876=spindle microtubule, 0005634=nucleus, 0005819=spindle, 0005813=centrosome" "l(2)05527, BcDNA:LD27161, Toc, CG9660, l(2)01361, BA34, l(2)k08224, unnamed, l(2)K08224" CG9660 16-Dec-15 2015_12 "ENSMUSG00000029651(Mtus2),ENSMUSG00000045636(Mtus1)" " adult stage && oogenesis stage | stage S3-8 , embryonic stage | early , adult stage , adult stage && oogenesis stage | late " " oocyte | posterior

, follicle cell | posterior

" "viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile,recessive,mitotic cell cycle defective,lethal,reduced" "spindle pole,spindle,fertilized egg,germline clone,dorsal appendage,egg,egg chamber,interfollicle cell,follicle cell,germarium,nurse follicle cell,spindlemat.ë±Tub67C.THsimVP16,spindle polemat.ë±Tub67C.THsimVP16,nuclear chromosomemat.ë±Tub67C.THsimVP16,spindle microtubulemat.ë±Tub67C.THsimVP16,kinetochore microtubulemat.ë±Tub67C.THsimVP16" DRSC00169 K 0.174891936 0.116633383 -0.132749219 0.854268538 0.835230738 1.988998114 FBgn0040341 CG11664 http://flybase.net/reports/FBgn0040341.html FBgn0029536 protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0032504=multicellular organism reproduction" 0005615=extracellular space "EG:BACR7A4.3, SP193" "IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG11664 16-Dec-15 2015_12 viable FBgn0003608 Su(var)206 Suppressor of variegation 206 http://flybase.net/reports/FBgn0003608.html gene 206 16-Dec-15 2015_12 "lethal,recessive,viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0040283 SMC1 Structural maintenance of chromosomes 1 http://flybase.net/reports/FBgn0040283.html FBgn0039146 protein_coding_gene "0003677=DNA binding, 0003682=chromatin binding, 0046982=protein heterodimerization activity, 0005524=ATP binding" "0007062=sister chromatid cohesion, 0016322=neuron remodeling, 0007064=mitotic sister chromatid cohesion, 0016319=mushroom body development, 0048813=dendrite morphogenesis, 0010629=negative regulation of gene expression" "0008278=cohesin complex, 0035327=transcriptionally active chromatin, 0005634=nucleus, 0005694=chromosome, 0005700=polytene chromosome" "smc1, Smc1 cohesin subunit, cohesin complex subunit SMC1, SMC1, dSMC1, cohesin subunit SMC1, cohesin, Smc1, AAF56231, DmSMC1, CG6057" "IPR024704=Structural maintenance of chromosomes protein, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR028468=Structural maintenance of chromosomes protein 1, IPR010935=SMCs flexible hinge, IPR003395=RecF/RecN/SMC, N-terminal" CG6057 16-Dec-15 2015_12 "ENSDARG00000058203,ENSDARG00000055754(smc1a)" YFL008W(SMC1) WBGene00001860(him-1) ENSXETG00000024747(SMC1A) "ENSMUSG00000041133(Smc1a),ENSMUSG00000022432(Smc1b)" "ENSG00000072501(SMC1A),ENSG00000077935(SMC1B)" "neuroanatomy defective,somatic clone,lethal,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,viable,fertile,visible,planar polarity defective" "mushroom body gamma-lobe,somatic clone,adult antennal lobe projection neuron VA3 adPN,antennal lobe projection neuron adPN,antennal lobe projection neuron lPN,antennal lobe projection neuron vPN,adult mushroom body,condensed chromosome,mesothoracic tergum,wing hair" DRSC16846 K -0.326822007 1.259834194 -0.551732022 0.475591937 0.885983003 1.701964689 FBgn0004368 Ptp4E Protein tyrosine phosphatase 4E http://flybase.net/reports/FBgn0004368.html protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0005001=transmembrane receptor protein tyrosine phosphatase activity" "0007417=central nervous system development, 0006470=protein dephosphorylation, 0007424=open tracheal system development, 0008045=motor neuron axon guidance" "0005886=plasma membrane, 0030424=axon, 0043025=neuronal cell body, 0016324=apical plasma membrane" "R-PTP 4E, PTP4E, 4E, unnamed, CT21187, CG6899, DPTP4E, PtP4E" "IPR000387=Tyrosine specific protein phosphatases domain, IPR000242=PTP type protein phosphatase, IPR003961=Fibronectin type III, IPR016130=Protein-tyrosine phosphatase, active site, IPR013783=Immunoglobulin-like fold, IPR029021=Protein-tyrosine phosphatase-like" CG6899 16-Dec-15 2015_12 WBGene00009717(dep-1) ENSXETG00000011378(PTPRB) ENSMUSG00000020154(Ptprb) ENSG00000127329(PTPRB) "viable,partially lethal - majority die,some die during pupal stage,fertile,neuroanatomy defective" ventral nerve cord FBgn0003612 Su(var)2-10 Suppressor of variegation 2-10 http://flybase.net/reports/FBgn0003612.html FBgn0010550 protein_coding_gene "0017151=DEAD/H-box RNA helicase binding, 0003677=DNA binding, 0008270=zinc ion binding" "0007095=mitotic G2 DNA damage checkpoint, 0046426=negative regulation of JAK-STAT cascade, 0048749=compound eye development, 0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0007446=imaginal disc growth, 0046425=regulation of JAK-STAT cascade, 0030261=chromosome condensation, 0030097=hemopoiesis, 0042176=regulation of protein catabolic process, 0022008=neurogenesis, 0051276=chromosome organization" "0005737=cytoplasm, 0005634=nucleus, 0035012=polytene chromosome, telomeric region, 0005700=polytene chromosome, 0005652=nuclear lamina, 0005654=nucleoplasm" "DmPias, Suvar(2)10, DPIAS, ZIMP, SU(VAR)2-10, Su(Var)2-10, pias, ZimpB, dPIAS, Su(var)-10, ZimpA, zimp, suppressor of variegation 2-10, CG8068, i184, l(2)03697, dpias, PIAS, CLOT2057, Dpias, protein inhibitor of activated STAT, zinc finger-containing Miz1 PIAS3-like, Su-var(2)10" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR023321=PINIT domain, IPR003034=SAP domain, IPR004181=Zinc finger, MIZ-type" CG8068 16-Dec-15 2015_12 "ENSDARG00000062445(si:dkey-9i9.1),ENSDARG00000036094(LOC564496),ENSDARG00000059831(pias2)" "YOR156C(NFI1),YDR409W(SIZ1)" WBGene00001574(gei-17) "ENSXETG00000007813(PIAS1),ENSXETG00000018642(PIAS3),ENSXETG00000021519(PIAS2)" "ENSMUSG00000032405(Pias1),ENSMUSG00000028101(Pias3),ENSMUSG00000025423(Pias2)" "ENSG00000033800(PIAS1),ENSG00000131788(PIAS3),ENSG00000078043(PIAS2)" " embryonic stage , embryonic stage | early , embryonic stage && adult stage , adult stage && oogenesis stage | stage >=S10 " "

ubiquitous , egg chamber

" "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,melanotic mass phenotype,mitotic cell cycle defective,meiotic cell cycle defective,dominant,suppressor of variegation,visible,wild-type,immune response defective,conditional,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "lens,somatic clone,eye,ommatidium,photoreceptor cell,polytene chromosome2-102),polytene chromosome2-101),interphase & nuclear chromosome2-101),polytene chromosome2-10Pex74a),border follicle cell,interphase & nuclear chromosome2-102),adult gut,embryonic/larval neuroblast,ganglion mother cell" DRSC07721 K 0.305912607 -0.833541624 0.479179244 -0.784448279 1.629817576 0.362200045 FBgn0013765 cnn centrosomin http://flybase.net/reports/FBgn0013765.html "FBgn0002675, FBgn0020264, FBgn0033839" protein_coding_gene "0005515=protein binding, 0008017=microtubule binding" "0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0055059=asymmetric neuroblast division, 0007417=central nervous system development, 0007494=midgut development, 0030997=regulation of centriole-centriole cohesion, 0008356=asymmetric cell division, 0000226=microtubule cytoskeleton organization, 0040016=embryonic cleavage, 0007098=centrosome cycle, 0016321=female meiosis chromosome segregation, 0007279=pole cell formation, 0051297=centrosome organization, 0008594=photoreceptor cell morphogenesis, 0007017=microtubule-based process, 0007099=centriole replication, 0000280=nuclear division" "0005737=cytoplasm, 0005813=centrosome, 0000242=pericentriolar material, 0016459=myosin complex, 0000922=spindle pole, 0005875=microtubule associated complex, 0005814=centriole" "cen, oblivious, CG 4832, Centrosmin, Cnn, mat(2)syn-C, CNN, obv, mfs, mat(2)synHK21, maternal effect syncytial blastoderm arrest C, Cnn1, CG18370, CG4832, Centrosomin" "IPR012943=Centrosomin, N-terminal motif 1" CG4832 16-Dec-15 2015_12 ENSDARG00000024219(zgc:55582) "ENSMUSG00000039298(Cdk5rap2),ENSMUSG00000038170(Pde4dip)" ENSG00000136861(CDK5RAP2) " embryonic stage | stage 10 , embryonic stage | stage 14 , embryonic stage | early , embryonic stage | stage 6,7 , embryonic stage | stage 5 , embryonic stage | stage 11 , adult stage | male , embryonic stage | stage 11-16 , adult stage | female " " neuroblast

, brain

, ventral furrow

, central nervous system

, peripheral nervous system

, cephalic furrow

, testis

, visceral mesoderm | restricted

, ovary

" " embryonic stage | stage 14-16 , embryonic stage | stage 6,7 , embryonic stage | stage 11 , embryonic stage | stage 5 , adult stage && oogenesis stage , adult stage | male , embryonic stage | stage 14 , embryonic stage | stage 4 , spermatogenesis && adult stage , embryonic stage , embryonic stage | stage 10 " " visceral mesoderm &&of midgut constriction 2

, ventral furrow

, peripheral nervous system

, ovary

, visceral mesoderm &&of gastric caecum

, spermatocyte

, testis

, brain

,

, central nervous system

, cephalic furrow

, neuroblast

, spermatogonium

" "viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,male sterile,meiotic cell cycle defective,dominant,male fertile,wild-type,female sterile,recessive,mitotic cell cycle defective,cytokinesis defective,male,cell cycle defective,non-suppressor of variegation,partially lethal - majority die,some die during pupal stage" "centriole,centrosomenos.UTR.THsimVP16,centriolar satellitenos.UTR.THsimVP16,centrosome | embryonic stage 4,pericentriolar material | embryonic stage 4,spindle | embryonic stage 4,embryonic cortex & actin filament,embryo,centrosome,spindle,mitotic cell cycle,spindle microtubule,maternal effect,nucleus | embryonic stage | maternal effect,nuclear chromosome | embryonic stage | maternal effect,spindle | embryonic stage | maternal effect,meiotic cell cycle | male,meiosis I & aster,spermatocyte,spermatid,male germline stem cell,supernumerary,cyst progenitor cell,cleavage furrow | embryonic stage,spindle | embryonic stage,pole cell,wing,neuroblast,male germline stem cell & spindle,male germline stem cell & centrosome,centrosome & male germline stem cell,somatic clone,ganglion mother cell,axoneme,spermatocyte & spindle,astral microtubule" DRSC07596 E 0.662958831 0.383168078 -0.308911937 2.657951947 0.045307453 -0.166702686 FBgn0025743 mbt mushroom bodies tiny http://flybase.net/reports/FBgn0025743.html "FBgn0025244, FBgn0026024, FBgn0044827" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0017048=Rho GTPase binding, 0004702=receptor signaling protein serine/threonine kinase activity" "0001751=compound eye photoreceptor cell differentiation, 0007010=cytoskeleton organization, 0046331=lateral inhibition, 0045315=positive regulation of compound eye photoreceptor development, 0006468=protein phosphorylation, 0045792=negative regulation of cell size, 0016319=mushroom body development, 0007030=Golgi organization, 0018105=peptidyl-serine phosphorylation, 0048749=compound eye development, 2000047=regulation of cell-cell adhesion mediated by cadherin, 0000187=activation of MAPK activity" "0005913=cell-cell adherens junction, 0005737=cytoplasm, 0005886=plasma membrane, 0005912=adherens junction" "STE20, Mushroom bodies tiny, Ste20, anon-fast-evolving-1G7, DmPAK2, anon-EST:fe1G7, DmMBT, dPAK2, Mbt, unnamed, Pak2, CG18582, PAK" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR000095=CRIB domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG18582 16-Dec-15 2015_12 "ENSDARG00000027564,ENSDARG00000052405(si:ch211-158b22.3)" WBGene00006443(pak-2) "ENSXETG00000015090(PAK7),ENSXETG00000005314(PAK4)" "ENSMUSG00000039913(Pak7),ENSMUSG00000030602(Pak4)" "ENSG00000101349(PAK7),ENSG00000130669(PAK4)" "viable,visible,recessive,fertile,body color defective,partially lethal - majority die,some die during pupal stage" "rhabdomere & eye photoreceptor cell,eye,ommatidium,eye photoreceptor cell,rhabdomere & eye photoreceptor cellelav.PLu,nucleus & eye photoreceptor cell | third instar larval stageelav.PLu,filamentous actin & eye photoreceptor cell | third instar larval stageelav.PLu,ommatidial precursor cluster | third instar larval stage,ommatidium | pupal stage P7,filamentous actin & ommatidium | pupal stage P7elav.PLu,cone cell | pupal stage P7,interommatidial bristle | pupal stage P7,pigment cell & retina | pupal stage P7elav.PLu,Kenyon cell,macrochaeta,lobe system of adult mushroom body,adult mushroom body,calyx of adult mushroom body,mushroom body & neuroblast,rhabdomere,ommatidial precursor cluster,interommatidial bristle,cone cell,supernumerary,adherens junction & ommatidium | pupal stage P7elav.PLu,chaeta,mesothoracic tergum" FBgn0002938 ninaC neither inactivation nor afterpotential C http://flybase.net/reports/FBgn0002938.html "FBgn0026796, FBgn0026835" protein_coding_gene "0005524=ATP binding, 0042623=ATPase activity, coupled, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0003774=motor activity, 0035091=phosphatidylinositol binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0005516=calmodulin binding" "0009416=response to light stimulus, 0033227=dsRNA transport, 0007010=cytoskeleton organization, 0007603=phototransduction, visible light, 0007604=phototransduction, UV, 0016059=deactivation of rhodopsin mediated signaling, 0006886=intracellular protein transport, 0006468=protein phosphorylation, 0045494=photoreceptor cell maintenance, 1990146=protein localization to rhabdomere, 0008104=protein localization, 0016062=adaptation of rhodopsin mediated signaling" "0005737=cytoplasm, 0005875=microtubule associated complex, 0016028=rhabdomere, 0016459=myosin complex, 0005856=cytoskeleton, 0016461=unconventional myosin complex, 0042385=myosin III complex, 0016027=inaD signaling complex" "either inactivation nor afterpotential C, neither inactivation nor afterpotential-C, NINA C, CG 5125, CT16120, myosin-III, NINAC myosin III, Dm NinaC, ninac, NinaC, Neither inactivation nor after potential C, Neither Inactivation Nor Afterpotential C, Nina C, CG54125, Droninac, myosin III, 2.2, NINAC, DRONINAC, CT42491, CG5125" "IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001609=Myosin head, motor domain, IPR000048=IQ motif, EF-hand binding site, IPR000719=Protein kinase domain" CG5125 16-Dec-15 2015_12 "ENSDARG00000010186(myo3a),ENSDARG00000006892(myo3b)" WBGene00003247(mig-15) "ENSXETG00000018850(MYO3B),ENSXETG00000018713(MYO3A)" "ENSMUSG00000042064(Myo3b),ENSMUSG00000025716(Myo3a)" "ENSG00000071909(MYO3B),ENSG00000095777(MYO3A)" adult stage head

adult stage " rhabdomere

, ocellus rhabdomere

, adult head

" "neurophysiology defective,visual behavior defective,wild-type,behavior defective,recessive,phototaxis defective,viable" "eye photoreceptor cell,eye,retina,photoreceptor cell,ommatidium,rhabdomere,male genitalia" FBgn0011591 fng fringe http://flybase.net/reports/FBgn0011591.html FBgn0011797 protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0008194=UDP-glycosyltransferase activity, 0033829=O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity" "0006004=fucose metabolic process, 0036011=imaginal disc-derived leg segmentation, 0007219=Notch signaling pathway, 0007293=germarium-derived egg chamber formation, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0045747=positive regulation of Notch signaling pathway, 0048477=oogenesis, 0048190=wing disc dorsal/ventral pattern formation, 0036099=female germ-line stem cell maintenance, 0008593=regulation of Notch signaling pathway, 0001708=cell fate specification, 0007476=imaginal disc-derived wing morphogenesis, 0045746=negative regulation of Notch signaling pathway, 0007450=dorsal/ventral pattern formation, imaginal disc, 0048749=compound eye development, 0035017=cuticle pattern formation, 0001745=compound eye morphogenesis, 0008587=imaginal disc-derived wing margin morphogenesis, 0006493=protein O-linked glycosylation" "0005795=Golgi stack, 0005797=Golgi medial cisterna, 0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005794=Golgi apparatus, 0030173=integral component of Golgi membrane" "D-Fng, frg, D-fng, Frg, fg, Fringe, fringe, CG10580, Fng, l(3)rG554, Dfng" "IPR003378=Fringe-like, IPR017374=Fringe" CG10580 16-Dec-15 2015_12 "ENSDARG00000019746(rfng),ENSDARG00000037879(lfng),ENSDARG00000042925(mfng)" ENSXETG00000021768(LFNG) "ENSMUSG00000025158(Rfng),ENSMUSG00000029570(Lfng),ENSMUSG00000018169(Mfng)" "ENSG00000169733(RFNG),ENSG00000106003(LFNG),ENSG00000100060(MFNG)" " adult stage && oogenesis stage | stage S2-4 , larval stage | second instar , larval stage | third instar , adult stage && oogenesis stage | stage S5 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S6-9 , adult stage && oogenesis stage | stage S10 " " polar follicle cell

, dorsal mesothoracic disc | dorsal

, dorsal mesothoracic disc | restricted

, follicle cell

, follicle cell &&of germarium region 2b

, follicle cell | subset

" "partially lethal - majority live,lethal,recessive,visible,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,dominant,cell non-autonomous,somatic clone,viable,cell shape defective,partially,decreased cell number" "wing,femur,somatic clone,tibia,wing vein L4,eye,ovary,interfollicle cell,follicle cell,denticle,ectopic,wing vein,ommatidium,photoreceptor,heat sensitive,egg chamber,dorsal appendage,egg,wing margin,anterior/posterior compartment boundary,trochanter,proventriculus inner layer primordium,proventriculus intermediate layer primordium,proventriculus outer layer primordium,embryonic proventriculus,keyhole structure,ocellar triangle,cell non-autonomous,eye equator,ventral,coxa,joint,cell autonomous,metatarsus,tarsal segment 2,tarsal segment 3,tarsal segment 4,antenna,maternal effect,wing disc,polar follicle cell,border follicle cell,nurse follicle cell,centripetally migrating follicle cell,oocyte,dorsal,filamentous actin & denticle field primordium,denticle row,pretarsus,eye disc,supernumerary,dorsal mesothoracic disc & filamentous actin | anterior/posterior compartment boundaryptc-559.1,wing margin bristle,leg,leg & jointDll-md23,anterior dorsocentral bristle,scutum,germarium cap cell,female germline stem cell" FBgn0010258 Rbp4 RNA-binding protein 4 http://flybase.net/reports/FBgn0010258.html protein_coding_gene "0003729=mRNA binding, 0003727=single-stranded RNA binding, 0000166=nucleotide binding" 0006397=mRNA processing 0005737=cytoplasm "Tsr, rrm4, CG9654, Testis specific RRM protein, RRM4, tsr, TSR" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG9654 16-Dec-15 2015_12 " pupal stage , adult stage | male , larval stage | third instar " adult stage | male " spermatid

, spermatocyte

, testis

" "male fertile,partially,female fertile,viable" FBgn0002579 RpL36 Ribosomal protein L36 http://flybase.net/reports/FBgn0002579.html "FBgn0025295, FBgn0040151, FBgn0047325" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005730=nucleolus, 0005840=ribosome, 0000228=nuclear chromosome, 0022625=cytosolic large ribosomal subunit, 0005737=cytoplasm" "M(1)Bld, EG:115C2.7, Minute(1)1B, l(1)1Bj, anon-EST:Posey274, BcDNA:AT29875, Vi, Rp L36, l(1)G0471, L36a, Viability, M(1)1B, Minute(1)Blond, CG7622" IPR000509=Ribosomal protein L36e CG7622 16-Dec-15 2015_12 ENSDARG00000013012(rpl36) "YPL249C-A(RPL36B),YMR194W(RPL36A)" WBGene00004450(rpl-36) ENSXETG00000027840(rpl36) "ENSMUSG00000066478(Gm5745),ENSMUSG00000057863(Rpl36),ENSMUSG00000066629(Rpl36-ps3),ENSMUSG00000066771(Gm5614),ENSMUSG00000064081(Gm8973)" "ENSG00000130255(RPL36),ENSG00000215696,ENSG00000215905" " embryonic stage , adult stage " "lethal,recessive,male sterile,wild-type,viable,reduced,visible,dominant,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" macrochaeta DRSC18708 EK -1.151808359 -0.472142542 4.061574815 -3.220535998 1.694584021 3.04597881 FBgn0030964 Pvf1 PDGF- and VEGF-related factor 1 http://flybase.net/reports/FBgn0030964.html "FBgn0029073, FBgn0044470" protein_coding_gene "0005172=vascular endothelial growth factor receptor binding, 0005102=receptor binding, 0008083=growth factor activity, 0008201=heparin binding" "2000683=regulation of cellular response to X-ray, 0007298=border follicle cell migration, 0007443=Malpighian tubule morphogenesis, 0035099=hemocyte migration, 0060548=negative regulation of cell death, 0030031=cell projection assembly, 0061327=anterior Malpighian tubule development, 0007435=salivary gland morphogenesis, 0048010=vascular endothelial growth factor receptor signaling pathway" "0005576=extracellular region, 0005737=cytoplasm, 0016020=membrane" "Pvf, vegf1, PVFs, DmVEGF-1, PVF, PVF1, VEGF2-B, l(1)G0146, pvf1, unnamed, CG7103, EP1624, Vegf17E, PDGF (platelet-derived growth factor)- and VEGF (vascular endothelial growth factor)-related factor 1, VEGF, Vegf17e-a, Vegf17e-b" "IPR000072=PDGF/VEGF domain, IPR029034=Cystine-knot cytokine" CG7103 16-Dec-15 2015_12 WBGene00004249(pvf-1) " embryonic stage | stage 10-15 , embryonic stage | stage 10-12 , embryonic stage | stage 13 , embryonic stage | stage >12 " " embryonic salivary gland

, posterior ectoderm

restricted , embryonic trachea

, embryonic trachea

restricted , Malpighian tubule

" "viable,reduced,fertile,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,partially lethal - majority die,recessive,wild-type" "border follicle cell,male terminalia,ejaculatory bulb,embryonic dorsal epidermis,intersegmental nerve,anterior fascicle & synapse,embryonic anterior Malpighian tubule,border follicle cell & filopodiumslbo.2.6,somatic clone,adult external abdomen,dorsal,cell non-autonomous" FBgn0038224 ATPsynE "ATP synthase, subunit E" http://flybase.net/reports/FBgn0038224.html protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0015986=ATP synthesis coupled proton transport, 0015992=proton transport" "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), 0005811=lipid particle" "CG3321, c550, anon-88Bd, ATPJ, ATP synthase E chain, ATP synthase e chain, F0/F1 ATP synthase E" "IPR008386=ATPase, F0 complex, subunit E, mitochondrial" CG3321 16-Dec-15 2015_12 ENSDARG00000068940(atp5i) ENSXETG00000026838(ATP5I) ENSMUSG00000050856(Atp5k) ENSG00000169020(ATP5I) "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0001311 kkv krotzkopf verkehrt http://flybase.net/reports/FBgn0001311.html "FBgn0013580, FBgn0037319, FBgn0043004" protein_coding_gene 0004100=chitin synthase activity "0006031=chitin biosynthetic process, 0007430=terminal branching, open tracheal system, 0007424=open tracheal system development, 0035158=regulation of tube diameter, open tracheal system, 0035159=regulation of tube length, open tracheal system, 0007443=Malpighian tubule morphogenesis, 0009611=response to wounding, 0060439=trachea morphogenesis, 0006035=cuticle chitin biosynthetic process, 0008362=chitin-based embryonic cuticle biosynthetic process, 0001838=embryonic epithelial tube formation" "0045177=apical part of cell, 0016021=integral component of membrane, 0005737=cytoplasm" "CG2666, Blimp, chitin synthase-1, Krotzkopf verkehrt, Kkv, DmCS-1, l(3)82Fh, krotzkopf-verkehrt, ChSB, Chitin Syn1, CS-1, CS-1/kkv, blimp, Chitin Synthase B, DmeChSB, short of breath, Chitin synthase 1" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR004835=Chitin synthase" CG2666 16-Dec-15 2015_12 "ENSDARG00000068951(si:ch211-219a15.4),ENSDARG00000068946(si:ch211-264e16.2),ENSDARG00000068947(si:ch211-264e16.1)" "YNL192W(CHS1),YBR038W(CHS2)" WBGene00000497(chs-2) "visible,somatic clone,neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "cephalopharyngeal skeleton,wing hair,somatic clone,embryonic epidermis,embryonic/first instar larval cuticle,rhabdomere of eye photoreceptor cell,embryo,denticle belt,embryonic/larval tracheal system,Malpighian tubule,ureter,embryonic/larval trachea,cuticle,presumptive embryonic/larval tracheal system,pupal epidermis,embryonic/larval dorsal trunk,dorsal trunk primordium,embryonic/larval dorsal trunk & procuticle,epicuticle,procuticle,hypostomal sclerite,vertical bridge,median tooth,terminal tracheal cell,eye" FBgn0043985 Su(rst)E290 Su(rst)E290 http://flybase.net/reports/FBgn0043985.html gene 0001745=compound eye morphogenesis E290 16-Dec-15 2015_12 viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0260365 GSd419 http://flybase.net/reports/FBgn0260365.html gene 16-Dec-15 2015_12 lethal FBgn0001330 kz kurz http://flybase.net/reports/FBgn0001330.html protein_coding_gene "0003676=nucleic acid binding, 0004386=helicase activity, 0008026=ATP-dependent helicase activity, 0005524=ATP binding" 0022008=neurogenesis 0005634=nucleus "EG:30B8.2, N8, N1, l(1)2Eb, CG3228, l67, l(1)N4" "IPR011545=DEAD/DEAH box helicase domain, IPR002464=DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR007502=Helicase-associated domain, IPR011709=Domain of unknown function DUF1605" CG3228 16-Dec-15 2015_12 ENSDARG00000062612(dhx37) YMR128W(ECM16) WBGene00015525(rha-2) ENSXETG00000001202(DHX37) ENSMUSG00000029480(Dhx37) ENSG00000150990(DHX37) " oogenesis stage && adult stage | female , embryonic stage | 0-6 hr " ovary

"lethal,recessive,wild-type,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0003401 shu shutdown http://flybase.net/reports/FBgn0003401.html FBgn0034912 protein_coding_gene "0003755=peptidyl-prolyl cis-trans isomerase activity, 0005528=FK506 binding" "0018208=peptidyl-proline modification, 0006457=protein folding, 0034587=piRNA metabolic process, 0048477=oogenesis" "0016020=membrane, 0070725=Yb body, 0043186=P granule, 0005737=cytoplasm" "Shu, CG4735, Shutdown, shut down" "IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR013105=Tetratricopeptide repeat 2, IPR011990=Tetratricopeptide-like helical domain" CG4735 16-Dec-15 2015_12 ENSDARG00000030133(si:dkey-189h5.5) ENSXETG00000024716(fkbp6) ENSMUSG00000040013(Fkbp6) ENSG00000077800(FKBP6) "viable,fertile,wild-type,female sterile,male sterile,recessive" "egg,dorsal appendage,egg chamber,oocyte,germline clone,nurse follicle cell,ovariole,germline cell,female,fusome | femaleb23)" FBgn0041342 Cct1 CTP:phosphocholine cytidylyltransferase 1 http://flybase.net/reports/FBgn0041342.html FBgn0035230 protein_coding_gene 0004105=choline-phosphate cytidylyltransferase activity "0006656=phosphatidylcholine biosynthetic process, 0042067=establishment of ommatidial planar polarity, 0007476=imaginal disc-derived wing morphogenesis, 0008340=determination of adult lifespan, 0009058=biosynthetic process, 0048477=oogenesis, 0006897=endocytosis, 0001654=eye development" 0005634=nucleus "CCT1, CTP:phosphocholine cytidylyltransferase, cct1, CG1049, cytidylyltransferase 1, Phosphocholine cytidylyltransferase, CT41283, Cct" "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR004821=Cytidyltransferase-like domain" CG1049 16-Dec-15 2015_12 "ENSDARG00000011233(pcyt1aa),ENSDARG00000004492(pcyt1ab),ENSDARG00000058162(pcyt1ba),ENSDARG00000044456" WBGene00017241(F08C6.2) "ENSXETG00000003079(PCYT1A),ENSXETG00000021820(PCYT1B)" "ENSMUSG00000005615(Pcyt1a),ENSMUSG00000035246(Pcyt1b)" "ENSG00000161217(PCYT1A),ENSG00000102230(PCYT1B)" "viable,partially lethal - majority live,developmental rate defective,planar polarity defective,female sterile,somatic clone,long lived,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,wild-type" "oocyte,egg chamber,germline cyst,ommatidium,eye photoreceptor cell,somatic clone,photoreceptor cell R3,photoreceptor cell R4,egg,maternal effect,fat body,lipid particle,ovariole,nurse cell spectrosome,female germline stem cell,basal stalk,dorsal appendage,egg operculum,germline clone,rhabdomere | larval stage | somatic clone,coated pit,coated vesicle,late endosome | larval stage,crossvein,supernumerary" DRSC08157 I -0.366494648 -1.658417982 -0.36197269 -0.70565282 -0.276655102 -0.387285075 FBgn0021818 cnk connector enhancer of ksr http://flybase.net/reports/FBgn0021818.html "FBgn0044753, FBgn0063794" protein_coding_gene "0019899=enzyme binding, 0005515=protein binding" "0070374=positive regulation of ERK1 and ERK2 cascade, 0008293=torso signaling pathway, 0046579=positive regulation of Ras protein signal transduction, 0007265=Ras protein signal transduction, 0007165=signal transduction, 0007476=imaginal disc-derived wing morphogenesis, 0007426=tracheal outgrowth, open tracheal system, 0008595=anterior/posterior axis specification, embryo, 0008586=imaginal disc-derived wing vein morphogenesis, 0001751=compound eye photoreceptor cell differentiation" "0005886=plasma membrane, 0045177=apical part of cell, 0005913=cell-cell adherens junction, 0005737=cytoplasm" "connector enhancer of KSR, anon-WO0257455.27, EK2-3, Connector Enhancer of KSR, connector enhancer of Ksr, CG6556, Cnk, CNK, EC2-3, Connector enhancer of KSR, l(2)k16314, anon-WO0140519.129, enhancer of KDN, Connector enhancer of Ksr" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR001849=Pleckstrin homology domain, IPR001478=PDZ domain, IPR017874=CRIC domain" CG6556 16-Dec-15 2015_12 ENSDARG00000032932(cnksr1) "ENSXETG00000010286(CNKSR2),ENSXETG00000017815(),ENSXETG00000009188(CNKSR1)" "ENSMUSG00000025658(Cnksr2),ENSMUSG00000028841(Cnksr1)" ENSG00000149970(CNKSR2) "viable,fertile,neuroanatomy defective,lethal,lethal - all die before end of larval stage,some die during larval stage,visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,wild-type" "synapse,imaginal disc,wing,wing vein,dorsal air sac primordium,somatic clone,eye,wing vein L4,eye photoreceptor cell,photoreceptor cell R7,ectopic,photoreceptor" DRSC07595 IEK -0.022204422 -5.816006724 -0.795623919 -6.929504739 -7.442955435 -5.343142981 FBgn0084745 fang fangorn http://flybase.net/reports/FBgn0084745.html gene "0007428=primary branching, open tracheal system" 16-Dec-15 2015_12 "presumptive embryonic/larval tracheal system,dorsal branch primordium,lateral trunk anterior branch" FBgn0039761 CG18404 http://flybase.net/reports/FBgn0039761.html FBgn0044778 protein_coding_gene 0022008=neurogenesis anon-WO0140519.106 CG18404 16-Dec-15 2015_12 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0034964 IntS1 Integrator 1 http://flybase.net/reports/FBgn0034964.html protein_coding_gene "0016180=snRNA processing, 0034472=snRNA 3'-end processing" 0032039=integrator complex "Int1, CG3173" "IPR022145=Domain of unknown function DUF3677, IPR016024=Armadillo-type fold" CG3173 16-Dec-15 2015_12 ENSDARG00000059631(ints1) WBGene00015499(C06A5.1) ENSXETG00000018110() ENSMUSG00000029547(Ints1) ENSG00000164880(INTS1) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04343 I 0.389503672 -2.503927134 0.560152028 -0.512653638 0.310050932 -0.942329829 FBgn0029068 l(1)G0236 lethal (1) G0236 http://flybase.net/reports/FBgn0029068.html gene 16-Dec-15 2015_12 "partially lethal - majority die,recessive,lethal" wing FBgn0025730 tbi tibi http://flybase.net/reports/FBgn0025730.html gene 16-Dec-15 2015_12 "lethal,polyphasic,rescuable maternal effect,visible,recessive" wing FBgn0026058 OdsH Ods-site homeobox http://flybase.net/reports/FBgn0026058.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0032504=multicellular organism reproduction" "0005634=nucleus, 0005615=extracellular space" "odsH, odsh, CG6352, OdsH[mel]" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG6352 16-Dec-15 2015_12 "ENSDARG00000020961(uncx),ENSDARG00000037760(uncx4.1)" WBGene00001174(egl-5) "viable,male fertile,reduced,male semi-sterile" "male germline stem cell,primary gonial cell,spermatogonium" FBgn0028688 Rpn7 Regulatory particle non-ATPase 7 http://flybase.net/reports/FBgn0028688.html "FBgn0046486, FBgn0046488" protein_coding_gene 0005515=protein binding "0022008=neurogenesis, 0006508=proteolysis, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005838=proteasome regulatory particle, 0008541=proteasome regulatory particle, lid subcomplex, 0000502=proteasome complex" "S10a, CG5378, 141231_at, anon-WO0172774.103, anon-WO0172774.106, Rpn7, p42A" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019585=26S proteasome, regulatory subunit Rpn7, IPR000717=Proteasome component (PCI) domain" CG5378 16-Dec-15 2015_12 ENSDARG00000070674(psmd6) YPR108W(RPN7) WBGene00004463(rpn-7) ENSXETG00000006537(psmd6) ENSMUSG00000021737(Psmd6) ENSG00000163636(PSMD6) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC16841 IEK -2.240030176 -4.280276004 -2.423479903 -2.107371086 1.638402825 -1.421385723 FBgn0000910 fs(1)M120 female sterile (1) M120 http://flybase.net/reports/FBgn0000910.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0004745 l(3)85Fb lethal (3) 85Fb http://flybase.net/reports/FBgn0004745.html gene 16-Dec-15 2015_12 lethal FBgn0000492 Dr Drop http://flybase.net/reports/FBgn0000492.html "FBgn0002849, FBgn0015510, FBgn0020528" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0007419=ventral cord development, 0035309=wing and notum subfield formation, 0007517=muscle organ development, 0009953=dorsal/ventral pattern formation, 0007485=imaginal disc-derived male genitalia development, 0007420=brain development, 0007400=neuroblast fate determination, 0007398=ectoderm development, 0042659=regulation of cell fate specification, 0007450=dorsal/ventral pattern formation, imaginal disc, 0007476=imaginal disc-derived wing morphogenesis, 0006355=regulation of transcription, DNA-templated, 0035222=wing disc pattern formation, 0007417=central nervous system development, 0021782=glial cell development, 0010629=negative regulation of gene expression, 0007389=pattern specification process" 0005634=nucleus "Drop, msh1, l(3)FA30, Muscle segment homeobox, lottchen, Msx, msh-1, Muscle specific homeobox, Dr-distal, Msh, muscle segment homeobox, CG1897, Dr/msh, msh, muscle-specific homeodomain, muscle-specific homeodomain 1, 153515_at, ltt, 99B, muscle specific homeobox" "IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG1897 16-Dec-15 2015_12 " embryonic stage | stage 11-13 , embryonic stage , embryonic stage | stage 11 , embryonic stage | stage 5-8 , embryonic stage | stage >=11 , embryonic stage | stage 10-12 , larval stage , embryonic stage | stage >=13 , embryonic stage | stage 12-15 , embryonic stage | stage 9-11 , embryonic stage | stage 9-12 , embryonic stage | stage 10,11 , embryonic stage | stage 4 , embryonic stage | stage 8 , embryonic stage -- adult stage , embryonic stage && pupal stage && adult stage " " embryonic/larval fat body

, embryonic/larval hindgut

, neuroblast NB2-4

, lateral ectoderm

, embryonic peripheral nervous system

, neuroblast

, dorsal mesothoracic disc | restricted

, external sensory organ precursor cell

, embryonic/larval foregut

, embryonic central nervous system

, somatic mesoderm

, salivary gland body primordium

, optic lobe | precursor

, ventral nerve cord primordium

, peripheral glial cell | precursor

, embryonic brain | precursor

, neuroblast NB4-3

, neuroblast NB5-4

, dorsal ectoderm

, neuroblast NB3-4

, central nervous system

, neuroblast NB6-4

" embryonic stage | stage 9-11 " ventral neurogenic region && embryonic intercalary segment | dorsal

, tritocerebral neuroblast | subset & dorsal

, procephalic neuroblast | subset & dorsal

, ventral neurogenic region && embryonic antennal segment | dorsal

, deuterocerebral neuroblast | subset & dorsal

" "lethal,neuroanatomy defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,uncoordinated,visible,dominant,viable,reduced,increased cell death,locomotor behavior defective,somatic clone,mitotic cell cycle defective,Minute,partially lethal - majority die,wild-type,semidominant,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,behavior defective" "genital disc,ejaculatory duct,male accessory gland,vas deferens,testis,apodeme,hypandrium,clasper long bristle,clasper,genital arch,posterior lobe,lateral plate,cardioblast,pericardial cell,heart primordium,glial cell,embryonic tritocerebrum,basal procephalic longitudinal glia cluster,deutero/tritocerebral embryonic fiber tract founder cluster,macrochaeta,eye,ommatidium,five-cell ommatidial precursor cluster,wing,wing margin,alula,wing vein,medial-most cell body glial cell,medial cell body glial cell,neuroblast,neuron,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,abdominal dorsal oblique muscle,mesothoracic lateral transverse muscle,metathoracic lateral transverse muscle,abdominal lateral transverse muscle,metathoracic ventral acute muscle,abdominal ventral acute muscle,wing hinge,wing sclerite,sensillum campaniformium of proximal dorsal radius,scutellum,scutum,chaeta,tegula,presumptive embryonic/larval central nervous system,neuropil associated CNS glial cell,frontal connective,embryonic/larval cervical connective,embryonic/larval tritocerebral commissure,embryonic/larval subesophageal ganglion,segment border muscle,RP2 motor neuron,longitudinal connective,commissure,U neuron,A1-7 ventral longitudinal muscle,A1-7 ventral oblique muscle 1,A1-7 ventral oblique muscle 2,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,mesothoracic dorsal acute muscle 3,metathoracic dorsal acute muscle,abdominal dorsal acute muscle,mesothoracic lateral longitudinal muscle,metathoracic lateral longitudinal muscle 1,abdominal lateral longitudinal muscle,abdominal dorsal transverse muscle,dorsal oblique muscle,dorsal transverse muscle,dorsal acute muscle,,A1-7 dorsal acute muscle 1,A1-7 dorsal oblique muscle 1,hypodermal muscle of larval abdominal 9,ventral midline,aCC neuron,pCC neuron,fpCC neuron,wing sensillum,mesothoracic tergum,morphogenetic furrow,interommatidial bristle,lens,embryonic/larval somatic muscle,trichogen cell" DRSC22708 IEK -0.975651904 -1.698039058 -1.607172171 -4.951681106 0.795958059 1.538469143 FBgn0002945 nkd naked cuticle http://flybase.net/reports/FBgn0002945.html "FBgn0036840, FBgn0036841" protein_coding_gene "0030165=PDZ domain binding, 0008270=zinc ion binding" "0007367=segment polarity determination, 0030178=negative regulation of Wnt signaling pathway, 0014018=neuroblast fate specification" "0005737=cytoplasm, 0005634=nucleus" "Naked cuticle, CG11614, Nkd, Naked, naked, CG18224" IPR011992=EF-hand domain pair CG11614 16-Dec-15 2015_12 "ENSDARG00000055271(nkd2),ENSDARG00000020053(nkd1),ENSDARG00000013174" "ENSMUSG00000031661(Nkd1),ENSMUSG00000021567(Nkd2)" " embryonic stage , larval stage , embryonic stage | early " " ventral thoracic disc

, organism | gap-rule

, imaginal disc

,

segmentally repeated , dorsal mesothoracic disc

" embryonic stage

segmentally repeated "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,somatic clone,wild-type,cell growth defective,planar polarity defective,lethal - all die before end of P-stage,some die during pharate adult stage,viable,fertile" "embryonic/first instar larval cuticle,sternite,denticle belt,cuticle,T1 beard,cephalopharyngeal skeleton,primordium of embryonic/larval spiracle,embryonic head,posterior spiracle primordium,embryonic/larval dorsal vessel,interommatidial bristle,somatic clone,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic gnathal segment,embryonic/larval somatic muscle,neuroblast NB7-3,neuroblast NB6-4,ectopic,embryonic epidermis & embryonic abdominal segment,embryonic epidermis,embryonic/larval spiracle,filzkorper,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval brain,Keilin's organ,abdominal ventral denticle belt,eye,abdominal sternite bristle,leg,wing,scutum,haltere,ventral,wing margin bristle,anterior crossvein,antenna,wing disc,dorsal compartment,wing hair,supernumerary" DRSC11376 K 0.358801754 -0.050080399 0.507997887 -0.31332821 0.511758555 -1.588749481 FBgn0004872 piwi piwi http://flybase.net/reports/FBgn0004872.html protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding, 0005515=protein binding" "0048133=male germ-line stem cell asymmetric division, 0007279=pole cell formation, 0001709=cell fate determination, 0030718=germ-line stem cell maintenance, 0031047=gene silencing by RNA, 0042078=germ-line stem cell division, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0006342=chromatin silencing, 0070868=heterochromatin organization involved in chromatin silencing, 0010529=negative regulation of transposition, 0016441=posttranscriptional gene silencing, 0000335=negative regulation of transposition, DNA-mediated, 0048132=female germ-line stem cell asymmetric division, 0016246=RNA interference, 0017145=stem cell division" "0000785=chromatin, 0031933=telomeric heterochromatin, 0005700=polytene chromosome, 0070725=Yb body, 0000791=euchromatin, 0005634=nucleus, 0005654=nucleoplasm, 0005829=cytosol, 0005737=cytoplasm, 0010369=chromocenter" "Piwi, PIWI, CG6122, P-element induced wimpy testis" "IPR003165=Piwi domain, IPR003100=PAZ domain, IPR012337=Ribonuclease H-like domain" CG6122 16-Dec-15 2015_12 "WBGene00004178(prg-1),WBGene00004179(prg-2)" " adult stage && oogenesis stage , embryonic stage | early " " ovary

, germarium region 2b

, terminal filament basal cell

, germarium region 2a

, epithelial sheath

" "female sterile,recessive,male sterile,suppressor of variegation,lethal,non-rescuable maternal effect,mitotic cell cycle defective,germline clone,increased cell death,viable,fertile,non-suppressor of variegation,dominant,enhancer of variegation,wild-type,male fertile" "ovary,testis,ovariole,egg,female germline stem cell,cell autonomous,somatic clone,non-rescuable maternal effect,germarium,germline cyst,cystoblast,embryo,germline clone,embryonic head,syncytial blastoderm embryo,male germline stem cell,pole cell,maternal effect,embryonic/larval cuticle,cephalopharyngeal skeleton,egg chamber,nurse cell spectrosome,ectopic,germline cell,female,spectrosome | ectopichs.PB,spectrosomehs.PB,supernumerary,heat sensitive,dorsal appendage" FBgn0005142 l(2)ff10 lethal (2) ff10 http://flybase.net/reports/FBgn0005142.html gene 16-Dec-15 2015_12 "lethal,recessive" "lens,somatic clone,cone cell,ommatidium" FBgn0035169 CG13890 http://flybase.net/reports/FBgn0035169.html protein_coding_gene 0004165=dodecenoyl-CoA delta-isomerase activity "0050829=defense response to Gram-negative bacterium, 0008152=metabolic process" "0005811=lipid particle, 0005777=peroxisome" "IPR001753=Crotonase superfamily, IPR029045=ClpP/crotonase-like domain" CG13890 16-Dec-15 2015_12 ENSDARG00000045461(zgc:92030) "YLR284C(ECI1),YOR180C(DCI1)" WBGene00001153(ech-4) ENSXETG00000018066(PECI) "ENSMUSG00000021416(1810022C23Rik),ENSMUSG00000021417(Peci)" ENSG00000198721(ECI2) "viable,fertile,long lived,oxidative stress response defective,starvation stress response defective" FBgn0030703 MSBP membrane steroid binding protein http://flybase.net/reports/FBgn0030703.html protein_coding_gene 0035100=ecdysone binding "0012505=endomembrane system, 0005886=plasma membrane" "Membrane steroid binding protein, dm_MSBP, CG9066, Steroid binding protein" IPR001199=Cytochrome b5-like heme/steroid binding domain CG9066 16-Dec-15 2015_12 "ENSDARG00000054172(pgrmc1),ENSDARG00000030237(pgrmc2)" YPL170W(DAP1) WBGene00006890(vem-1) ENSXETG00000022520(pcrmc2) "ENSMUSG00000006373(Pgrmc1),ENSMUSG00000049940(Pgrmc2)" "ENSG00000101856(PGRMC1),ENSG00000164040(PGRMC2)" viable FBgn0025686 Amnionless Amnionless ortholog http://flybase.net/reports/FBgn0025686.html FBgn0031246 protein_coding_gene "0097017=renal protein absorption, 0097206=nephrocyte filtration, 0046331=lateral inhibition" 0016021=integral component of membrane "BEST:CK02467, dAMN, Amnionless, CK02467, CG11592" IPR026112=Amnionless CG11592 16-Dec-15 2015_12 ENSDARG00000062947 ENSXETG00000012751(AMN) ENSG00000166126(AMN) "chemical sensitive,viable,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval pericardial cell,chaeta" FBgn0024355 Fab-8 Fab-8 http://flybase.net/reports/FBgn0024355.html insulator "PTS, Frontabdominal-8, Fab8" 16-Dec-15 2015_12 visible eye FBgn0034484 CG11044 http://flybase.net/reports/FBgn0034484.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO10 IPR001810=F-box domain CG11044 16-Dec-15 2015_12 "ENSDARG00000021882,ENSDARG00000000722(fbxl3a),ENSDARG00000037738(LOC564855)" WBGene00019294(K02A6.3) ENSMUSG00000070388(Fbxo39) "viable,fertile" DRSC06026 E -1.115933391 -0.396187338 -1.541271919 0.301541866 -0.54102196 0.454534871 FBgn0005655 PCNA Proliferating cell nuclear antigen http://flybase.net/reports/FBgn0005655.html "FBgn0002895, FBgn0003045, FBgn0004700, FBgn0010513, FBgn0010677" protein_coding_gene "0003677=DNA binding, 0030337=DNA polymerase processivity factor activity" "0006298=mismatch repair, 0006275=regulation of DNA replication, 0006261=DNA-dependent DNA replication, 0006289=nucleotide-excision repair, 0006272=leading strand elongation, 0019730=antimicrobial humoral response, 0022008=neurogenesis, 0007307=eggshell chorion gene amplification, 0006260=DNA replication, 0007052=mitotic spindle organization" "0043626=PCNA complex, 0005875=microtubule associated complex" "pcna, proliferating-cell nuclear antigen, Mus209, dPCNA, mutagen-sensitive 209, l(2)02448, mus 209, DmPCNA, PCNA, Pcna, l(2)56Fa, l(2)s1534, l(2)56F, Proliferating-cell-nuclear-antigen, PCNA/mus209, MUS209, mus209, CG9193, 53/13, proliferating cell nuclear antigen" "IPR000730=Proliferating cell nuclear antigen, PCNA, IPR022648=Proliferating cell nuclear antigen, PCNA, N-terminal, IPR022649=Proliferating cell nuclear antigen, PCNA, C-terminal, IPR022659=Proliferating cell nuclear antigen, PCNA, conserved site" CG9193 16-Dec-15 2015_12 ENSDARG00000054155(pcna) YBR088C(POL30) WBGene00003955(pcn-1) ENSXETG00000008193(Q66KJ8_XENTR) ENSMUSG00000027342(Pcna) ENSG00000132646(PCNA) " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

egg stage | fertilized egg " male pronucleus

, female pronucleus

" "lethal,neuroanatomy defective,endomitotic cell cycle defective,recessive,wild-type,cold sensitive,female sterile,suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,DNA repair defective,female" "embryonic/larval neuroblast,ganglion mother cell,subperineurial glial cell,larval outer optic anlage,mitotic cell cycle,mitotic metaphase,spindle,mitosis & nuclear chromosome,chromosome, centromeric region,macrochaeta,posterior scutellar bristle,nurse cell,ectopic,larval optic anlage,somatic clone,sex comb,prothoracic leg,ovary,ovariole,follicle cell,nucleus | embryonic stage 4" DRSC07653 K -1.086117722 -0.269921659 -1.363834348 -0.752420911 2.665192719 4.660477752 FBgn0060302 ms28E ms28E http://flybase.net/reports/FBgn0060302.html gene 16-Dec-15 2015_12 spermatid FBgn0013672 mt:ATPase6 mitochondrial ATPase subunit 6 http://flybase.net/reports/FBgn0013672.html FBgn0002867 protein_coding_gene "0046933=proton-transporting ATP synthase activity, rotational mechanism, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" "0040011=locomotion, 0050877=neurological system process, 0015986=ATP synthesis coupled proton transport, 0042776=mitochondrial ATP synthesis coupled proton transport, 0043462=regulation of ATPase activity, 0046716=muscle cell cellular homeostasis, 0070050=neuron cellular homeostasis, 0008340=determination of adult lifespan" "0005739=mitochondrion, 0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATPase 6, ATP6, mtATP6, mitochondrial ATP6, ATPase6, CG34073, ATPase 6 gene, atp6" "IPR000568=ATPase, F0 complex, subunit A, IPR023011=ATPase, F0 complex, subunit A, active site" CG34073 16-Dec-15 2015_12 ENSDARG00000063911 Q0085(ATP6) WBGene00010960(MTCE.12) ENSMUSG00000064357 ENSG00000198899 "paralytic,short lived,neuroanatomy defective,locomotor behavior defective,bang sensitive,progressive,neurophysiology defective,developmental rate defective,stress response defective" "adult somatic muscle,flight muscle,thoracico-abdominal ganglion,mitochondrial crista,mitochondrial inner membrane" FBgn0013486 l(1)5PP1 lethal (1) 5PP1 http://flybase.net/reports/FBgn0013486.html gene 16-Dec-15 2015_12 "lethal,recessive,germline clone,maternal effect" "embryonic/first instar larval cuticle,germline clone" FBgn0028341 Ptpmeg2 Protein tyrosine phosphatase Meg2 http://flybase.net/reports/FBgn0028341.html "FBgn0030146, FBgn0030147, FBgn0052697" protein_coding_gene "0004726=non-membrane spanning protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0022008=neurogenesis, 0006909=phagocytosis, 0006470=protein dephosphorylation" 0005829=cytosol "PTP-Meg2, CG32697, dMeg2, CG3101, unnamed, L(1)G0232, MEG2, l(1)G0232, lG0232, lethal (1) G0232, CG3102" "IPR011074=CRAL/TRIO, N-terminal domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR029021=Protein-tyrosine phosphatase-like, IPR001251=CRAL-TRIO lipid binding domain, IPR016130=Protein-tyrosine phosphatase, active site, IPR000242=PTP type protein phosphatase" CG32697 16-Dec-15 2015_12 ENSXETG00000017990() ENSMUSG00000032290(Ptpn9) ENSG00000169410(PTPN9) "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0004876 cdi center divider http://flybase.net/reports/FBgn0004876.html FBgn0010912 protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0045873=negative regulation of sevenless signaling pathway, 0006468=protein phosphorylation, 0001700=embryonic development via the syncytial blastoderm, 0007015=actin filament organization" "0005737=cytoplasm, 0045177=apical part of cell" "91F gene, Center divider, unnamed, 91F, l(3)07013, centrer divider, CDI/TSKI, Cdi, Cdi/TESK1, CG6027, cdi/TESK1, central divider, B9.3, Centre divider" "IPR017441=Protein kinase, ATP binding site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG6027 16-Dec-15 2015_12 "viable,lethal,recessive,fertile,fully,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,body color defective" "photoreceptor cell R7,filamentous actin | somatic clone,intersegmental nerve,anterior fascicle & synapse,macrochaeta,embryonic head,embryonic segment,embryonic/first instar larval cuticle,head,segment,nervous system,actin filament | somatic cloneGMR.PU, mRpL55UAS.cSa,mesothoracic tergum" FBgn0017579 RpL14 Ribosomal protein L14 http://flybase.net/reports/FBgn0017579.html "FBgn0025288, FBgn0025308" protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0043524=negative regulation of neuron apoptotic process, 0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0051297=centrosome organization" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome, 0022626=cytosolic ribosome" "rpl14, L14, Minute (3)66D, Rp L14, ribosomal protein L14, M(3), M66D, 60 S ribosomal protein L14, CG6253, M(3)66D, anon-EST:Posey193U, M(3)66, Minute(3)66D, RPL14, anon-EST:Posey6" "IPR014722=Ribosomal protein L2 domain 2, IPR008991=Translation protein SH3-like domain, IPR002784=Ribosomal protein L14" CG6253 16-Dec-15 2015_12 ENSDARG00000036174(rpl14) "YKL006W(RPL14A),YHL001W(RPL14B)" WBGene00004426(rpl-14) "ENSXETG00000022018(rpl14),ENSXETG00000000809()" ENSMUSG00000025794(Rpl14) "ENSG00000188846(RPL14),ENSG00000139239" embryonic stage -- adult stage "visible,dominant,lethal,heat sensitive,Minute,some die during immature adult stage,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,developmental rate defective,partially lethal - majority live,cell growth defective,somatic clone,cell non-autonomous" "macrochaeta,chaeta,heat sensitive,anterior scutellar bristle,posterior scutellar bristle,posterior dorsocentral bristle,adult head,eye-antennal disc,thoracico-abdominal ganglion | pharate adult stage,embryonic/larval salivary gland,eye,interommatidial bristle,pigment cell,ommatidium,cornea,pseudocone,leg,wing,wing vein,arista,scutellum,postvertical bristle,microchaeta,wing disc,scutellar bristle" DRSC11269 EK -0.68890909 -0.967008998 0.145064601 -4.900551248 0.662543845 2.842837956 FBgn0034511 GNBP-like3 GNBP-like 3 http://flybase.net/reports/FBgn0034511.html protein_coding_gene 0030246=carbohydrate binding "0098542=defense response to other organism, 0009595=detection of biotic stimulus, 0009620=response to fungus" 0009986=cell surface "GNBP-like, Gram-negative binding protein-like protein, CG13422, GNBPlike 3" CG13422 16-Dec-15 2015_12 "immune response defective,short lived,conditional,viable" FBgn0005307 ms(1)RA40 male sterile (1) RA40 http://flybase.net/reports/FBgn0005307.html gene 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective" "meiotic cell cycle | male,meiotic cell cycle & spindle | male,spermatid" FBgn0021895 ytr yantar http://flybase.net/reports/FBgn0021895.html FBgn0034916 protein_coding_gene 0003729=mRNA binding "0030097=hemopoiesis, 0000398=mRNA splicing, via spliceosome, 0042386=hemocyte differentiation" 0071011=precatalytic spliceosome "bgcn, l(2)k13108, YTR, l(2)k13214, CG18426, l(2)60A-F, b(2)gcn" IPR013957=Domain of unknown function DUF1777 CG18426 16-Dec-15 2015_12 ENSDARG00000035625(snrnp27) WBGene00011035(R05D11.7) ENSXETG00000008518(Q6DDA4_XENTR) ENSMUSG00000001158(Snrnp27) ENSG00000124380(SNRNP27) "lethal,recessive,viable,fertile" "hemocyte,supernumerary,lamellocyte,embryonic/larval lymph gland,hemocyte & nucleus | supernumerary,crystal cell,embryonic/larval hemocyte" FBgn0001851 l(1)ts6225 lethal (1) ts6225 http://flybase.net/reports/FBgn0001851.html gene 16-Dec-15 2015_12 "lethal,heat sensitive" FBgn0020836 l(2)M10 Massachusetts 10 http://flybase.net/reports/FBgn0020836.html gene l(2)Mass.-10 16-Dec-15 2015_12 "lethal,recessive,visible,sterile" "pigment cell,wing" FBgn0004914 Hnf4 Hepatocyte nuclear factor 4 http://flybase.net/reports/FBgn0004914.html FBgn0032062 protein_coding_gene "0008270=zinc ion binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003707=steroid hormone receptor activity, 0043565=sequence-specific DNA binding" "0007498=mesoderm development, 0006355=regulation of transcription, DNA-templated, 0016042=lipid catabolic process, 0008610=lipid biosynthetic process, 0034440=lipid oxidation, 0043401=steroid hormone mediated signaling pathway, 0007492=endoderm development" 0005634=nucleus "Hnf-4, hepatocyte nuclear factor 4, DmHNF4, HNF-4(D), Hepatocyte nuclear factor 4 homologue, dHNF-4, dHNF4, HNF4, CG9310, HNF4alpha, HNF-4, Hnf-4h, NR2A4" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000003=Retinoid X receptor/HNF4, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type" CG9310 16-Dec-15 2015_12 WBGene00003628(nhr-35) "ENSMUSG00000017688(Hnf4g),ENSMUSG00000017950(Hnf4a)" "ENSG00000101076(HNF4A),ENSG00000164749(HNF4G)" " embryonic stage | stage 1-2 , embryonic stage | stage 11 , embryonic stage | stage 14-15 , embryonic stage " " posterior midgut proper primordium

, Malpighian tubule

, embryonic/larval salivary gland

, anterior midgut proper primordium

, embryonic/larval fat body

" "viable,fertile,stress response defective,eclosion defective,lethal,some die during immature adult stage,recessive" FBgn0000247 ca claret http://flybase.net/reports/FBgn0000247.html "FBgn0039699, FBgn0039700, FBgn0039701, FBgn0051037" protein_coding_gene "0017137=Rab GTPase binding, 0017112=Rab guanyl-nucleotide exchange factor activity" "0010506=regulation of autophagy, 0006856=eye pigment precursor transport, 0032483=regulation of Rab protein signal transduction, 0006727=ommochrome biosynthetic process, 0060967=negative regulation of gene silencing by RNA, 0008057=eye pigment granule organization, 0010883=regulation of lipid storage" "CG18134, bw-p, CG18133, Claret, bw[G], CG7799, CG31037, Rab32 GEF" "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG31037 16-Dec-15 2015_12 "visible,recessive,eye color defective,wild-type,female sterile,male sterile,viable" "ocellus,pigment cell,eye,Malpighian tubule,wing,abdomen,primary pigment cell pigment granule,secondary pigment cell pigment granule,tertiary pigment cell pigment granule,male genitalia,female genitalia" FBgn0045866 bai baiser http://flybase.net/reports/FBgn0045866.html "FBgn0039262, FBgn0061395" protein_coding_gene 0005215=transporter activity "0000003=reproduction, 0009953=dorsal/ventral pattern formation, 0048042=regulation of post-mating oviposition, 0048193=Golgi vesicle transport, 0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0016192=vesicle-mediated transport" "0016021=integral component of membrane, 0012505=endomembrane system, 0005795=Golgi stack" "150547_at, Baiser, p24, BcDNA:RE52411, BAI, CG11785, p23" "IPR009038=GOLD domain, IPR015720=TMP21-related" CG11785 16-Dec-15 2015_12 ENSDARG00000041391(tmed10) YML012W(ERV25) WBGene00009829(F47G9.1) "ENSXETG00000013236(TGas127a10.1),ENSXETG00000020604(BC080371.1)" ENSMUSG00000021248(Tmed10) ENSG00000170348(TMED10) "partially lethal - majority die,lethal,maternal effect,partially lethal - majority live,recessive,female sterile,male semi-sterile,germline clone,non-rescuable maternal effect,viable,female semi-sterile" "embryonic/first instar larval cuticle,dorsal,germline clone,wing vein,ectopic" FBgn0020521 pio piopio http://flybase.net/reports/FBgn0020521.html FBgn0035030 protein_coding_gene "0007424=open tracheal system development, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0040005=chitin-based cuticle attachment to epithelium, 0008362=chitin-based embryonic cuticle biosynthetic process" 0045177=apical part of cell "Piopio, CG30167, CG3541, piopio, PioPio, Pio" IPR001507=Zona pellucida domain CG3541 16-Dec-15 2015_12 "WBGene00011443(cutl-11),WBGene00013180(cutl-10),WBGene00013960(cutl-8),WBGene00012165(cutl-6),WBGene00010893(cutl-9),WBGene00000853(cut-6),WBGene00012304(cutl-4),WBGene00021025(cutl-13),WBGene00017351(cutl-5),WBGene00009979(cutl-1),WBGene00013145(cutl-2)" "viable,fertile,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval tracheal system,wing,somatic clone,embryonic/larval somatic muscle,segment,posterior,cerebral branch,ventral cephalic branch,pharyngeal branch,dorsal branch,visceral branch,lateral trunk anterior branch,lateral trunk posterior branch,adult external thorax,wing blade,cytoplasmic microtubule & wing | somatic clone,embryonic/first instar larval cuticle,embryonic/larval tracheal system,endocuticle" FBgn0002359 l(3)87Eg lethal (3) 87Eg http://flybase.net/reports/FBgn0002359.html FBgn0011806 gene "l(3)m17, 1437/04, l(3)s2149, 0616/17, m17" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" FBgn0000559 EF2 Elongation factor 2 http://flybase.net/reports/FBgn0000559.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003746=translation elongation factor activity" "0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0006414=translational elongation, 0006412=translation" "0005875=microtubule associated complex, 0005811=lipid particle, 0005829=cytosol, 0005737=cytoplasm" "CG2238, eF2, Ef2, EF2b, Elongation factor 2, EF-2, Ef2b, anon-EST:Liang-1.44, Elongation factor 2b, eEF2, ef2b, EF-2b, EF2, clone 1.44, eukaryotic translation elongation factor 2b, chr2L:21668915..21669164" "IPR009022=Elongation factor G, III-V domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR005517=Translation elongation factor EFG/EF2, domain IV, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000640=Translation elongation factor EFG, V domain, IPR005225=Small GTP-binding protein domain, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR031157=Tr-type G domain, conserved site, IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain" CG2238 16-Dec-15 2015_12 "ENSDARG00000003016(eef2l),ENSDARG00000035256(eef2l2),ENSDARG00000042094(zgc:113191)" "YOR133W(EFT1),YDR385W(EFT2)" WBGene00001167(eft-2) "ENSXETG00000021508(Q5FVX0_XENTR),ENSXETG00000006391(Q6P3N8_XENTR)" ENSMUSG00000034994(Eef2) ENSG00000167658(EEF2) lethal DRSC03737 IE -1.978513292 -1.655755324 -0.951468627 -2.780725022 -1.305737747 0.318067274 FBgn0032816 Nf-YB Nuclear factor Y-box B http://flybase.net/reports/FBgn0032816.html FBgn0062432 protein_coding_gene "0000976=transcription regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity" "0045893=positive regulation of transcription, DNA-templated, 0043066=negative regulation of apoptotic process, 0045678=positive regulation of R7 cell differentiation, 0043410=positive regulation of MAPK cascade, 0006351=transcription, DNA-templated, 0048749=compound eye development" 0016602=CCAAT-binding factor complex "dNF-YB, BcDNA:RH50436, NF-YB, CG10447, nuclear factor Y-box B" "IPR009072=Histone-fold, IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain" CG10447 16-Dec-15 2015_12 "ENSDARG00000068879(LOC556791),ENSDARG00000045611(nfybb),ENSDARG00000039185(nfyba)" YBL021C(HAP3) ENSXETG00000019656(NFYB) ENSMUSG00000020248(Nfyb) ENSG00000120837(NFYB) "viable,increased cell death,mitotic cell cycle defective" "eye,ommatidium,interommatidial bristle,eye disc posterior to the morphogenetic furrow,photoreceptor cell R7 | third instar larval stage" FBgn0052350 Vps11 Vacuolar protein sorting 11 http://flybase.net/reports/FBgn0052350.html "FBan0032350, FBgn0062459" protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0015031=protein transport, 0007041=lysosomal transport, 0016197=endosomal transport, 0016574=histone ubiquitination, 0000046=autophagic vacuole fusion, 0009267=cellular response to starvation, 0035542=regulation of SNARE complex assembly" "0030897=HOPS complex, 0033263=CORVET complex" "vacuolar protein sorting 11, BcDNA:LD20292, Vps11, CG32350" "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR016528=Vacuolar protein sorting-associated protein 11" CG32350 16-Dec-15 2015_12 ENSDARG00000036338(zgc:112329) WBGene00011067(vps-11) "ENSXETG00000010083(),ENSXETG00000010084()" ENSMUSG00000032127(Vps11) ENSG00000160695 "viable,body color defective" "embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditional,autophagic vacuole | supernumerary | wandering third instar larval stage | nutrition conditional,mesothoracic tergum,somatic clone,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0000802 fs(1)de13 female sterile (1) defective eggs 13 http://flybase.net/reports/FBgn0000802.html gene de13 16-Dec-15 2015_12 female sterile "dorsal appendage,chorion,endochorion" FBgn0038068 CG11600 http://flybase.net/reports/FBgn0038068.html protein_coding_gene 0004806=triglyceride lipase activity 0006629=lipid metabolic process "IPR006693=Partial AB-hydrolase lipase domain, IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold" CG11600 16-Dec-15 2015_12 YKL140W(TGL1) viable DRSC14332 K 0.298879353 -0.287267075 -0.23162695 0.356861871 0.775563978 -1.601275645 FBgn0033687 CG8407 http://flybase.net/reports/FBgn0033687.html protein_coding_gene "0042623=ATPase activity, coupled" "0007017=microtubule-based process, 0007018=microtubule-based movement" "0030286=dynein complex, 0005875=microtubule associated complex" "IPR001372=Dynein light chain, type 1/2" CG8407 16-Dec-15 2015_12 "ENSDARG00000053360,ENSDARG00000031116(zgc:100999)" ENSXETG00000006905(dnal4) ENSMUSG00000022420(Dnalc4) ENSG00000100246(DNAL4) viable FBgn0000332 Cma Comma http://flybase.net/reports/FBgn0000332.html gene 16-Dec-15 2015_12 "visible,dominant,flightless,lethal,recessive" "dorsal mesothorax,dorsocentral bristle,adult cuticle,myofibril & indirect flight muscle" FBgn0021765 scu scully http://flybase.net/reports/FBgn0021765.html FBgn0001550 protein_coding_gene "0004303=estradiol 17-beta-dehydrogenase activity, 0047022=7-beta-hydroxysteroid dehydrogenase (NADP+) activity, 0047035=testosterone dehydrogenase (NAD+) activity, 0018454=acetoacetyl-CoA reductase activity, 0016229=steroid dehydrogenase activity, 0003857=3-hydroxyacyl-CoA dehydrogenase activity" "0006637=acyl-CoA metabolic process, 0008209=androgen metabolic process, 0008205=ecdysone metabolic process, 0008202=steroid metabolic process, 0006631=fatty acid metabolic process, 0008210=estrogen metabolic process" "0005875=microtubule associated complex, 0005829=cytosol, 0005739=mitochondrion, 0005811=lipid particle" "HLII, CG7113, lethal(1)17Ad, Scully, l(1)16Fd, HL-X, 17beta-HSD10, 3-hydroxyacyl-CoA dehydrogenase, l(1)17Ad, haplo-lethal region II, Scu" "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site" CG7113 16-Dec-15 2015_12 ENSDARG00000017781(hsd17b10) WBGene00000181(ard-1) ENSXETG00000007721(hadh2) ENSMUSG00000025260(Hsd17b10) ENSG00000072506(HSD17B10) " adult stage | female , larval stage | third instar , larval stage , embryonic stage , embryonic stage | late , adult stage | male " " imaginal disc

, gonad

, Malpighian tubule

, gonad | primordium

, embryonic/larval salivary gland

, epithelial cell &&of midgut

, larval central nervous system

" "lethal,some die during pupal stage,viable,fertile,recessive,wild-type,neurophysiology defective,germline clone,polyphasic,lethal - all die before end of pupal stage" "oogonial cell,germline clone,spermatocyte,testis,spermatocyte & mitochondrion,ommatidium,somatic clone,eye photoreceptor cell,rhabdomere,eye photoreceptor cell & mitochondrion | somatic clone,spermatocyte & nucleolus" FBgn0036099 CG11811 http://flybase.net/reports/FBgn0036099.html protein_coding_gene 0004385=guanylate kinase activity 0006163=purine nucleotide metabolic process "0005737=cytoplasm, 0005634=nucleus" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR020590=Guanylate kinase, conserved site, IPR017665=Guanylate kinase, IPR008144=Guanylate kinase-like domain" CG11811 16-Dec-15 2015_12 "ENSDARG00000005776(guk1),ENSDARG00000030340(zgc:86776)" YDR454C(GUK1) WBGene00020190(T03F1.8) ENSXETG00000013914(BC064272.1) ENSMUSG00000020444(Guk1) "viable,fertile,visible" trichogen cell FBgn0000308 chic chickadee http://flybase.net/reports/FBgn0000308.html FBgn0013731 protein_coding_gene "0003779=actin binding, 0005515=protein binding, 0005546=phosphatidylinositol-4,5-bisphosphate binding" "0007488=histoblast morphogenesis, 0045451=pole plasm oskar mRNA localization, 0007391=dorsal closure, 0007015=actin filament organization, 0007411=axon guidance, 0030717=karyosome formation, 0035193=larval central nervous system remodeling, 0000902=cell morphogenesis, 0000915=actomyosin contractile ring assembly, 0007420=brain development, 0007300=ovarian nurse cell to oocyte transport, 0008154=actin polymerization or depolymerization, 0048680=positive regulation of axon regeneration, 0035019=somatic stem cell maintenance, 0042060=wound healing, 0051491=positive regulation of filopodium assembly, 0007436=larval salivary gland morphogenesis, 0016322=neuron remodeling, 0032507=maintenance of protein location in cell, 0030041=actin filament polymerization, 0007283=spermatogenesis, 0000281=mitotic cytokinesis, 0036098=male germ-line stem cell maintenance" "0005737=cytoplasm, 0043005=neuron projection, 0048471=perinuclear region of cytoplasm" "chickadee, stranded, Chic, Chickadee, Chi, GH4, chickaddee, CG9553, D88, DProfilin, sand, Profilin, profilin, l(2)27/7, chi, chicadee" "IPR005455=Profilin, IPR027310=Profilin conserved site" CG9553 16-Dec-15 2015_12 YOR122C(PFY1) WBGene00003991(pfn-3) "ENSXETG00000015309(),ENSXETG00000020090(PFN2)" ENSMUSG00000020639(Pfn4) ENSG00000176732(PFN4) " adult stage | male , oogenesis stage && adult stage | female " ovary

" embryonic stage | stage 16 , embryonic stage -- adult stage , adult stage && oogenesis stage , embryonic stage " " ventral nerve cord

, nurse cell

, follicle cell

, border follicle cell

" "female sterile,recessive,male sterile,visible,neuroanatomy defective,somatic clone,lethal,female semi-sterile,cell shape defective,dominant,maternal effect,wound healing defective,male fertile,female fertile,poor,viable,fertile,male semi-sterile,cytokinesis defective,male,partially lethal - majority die,axis specification defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,onion stage spermatid,aster & meiotic cell cycle | male,nurse cell,border follicle cell,oocyte,egg chamber,nurse cell ring canal,egg,karyosome,embryonic/larval salivary gland,stage S8 oocyte,maternal effect,chorion | maternal effect,dorsal appendage,follicle cell,somatic clone,stress fiber | somatic clone,testis,contractile ring & meiotic cell cycle | male,spindle & meiotic cell cycle | male,secondary spermatocyte,spermatocyte,cleavage furrow & spermatocyte,longitudinal connective,filopodium,adult mushroom body,follicle cell & actin filament | somatic clone,embryonic/larval neuron,intersegmental nerve,filopodiumGpdhA),motor neuron,spermatocyte ring canal,spermatid,meiotic cell cycle,Nebenkern,crossvein,ectopic,embryonic/first instar larval cuticle,dorsal,embryonic dorsal epidermis,embryonic leading edge cell,photoreceptor cell & eye disc | somatic clone,actin filament & eye disc | somatic clone,morphogenetic furrow,wing,embryonic somatic muscle,anterior embryonic/larval midgut,embryonic proventriculus,cyst cell,sternopleural bristle,germarium,microchaeta,LNv neuron,ventral adult lateral neuron & commissureP2.4.Pdf,histoblast nest,adult abdomen,embryonic epidermis,trichogen cell & actin filament & pupa" FBgn0017418 ari-1 ariadne 1 http://flybase.net/reports/FBgn0017418.html FBgn0014203 protein_coding_gene "0031624=ubiquitin conjugating enzyme binding, 0061630=ubiquitin protein ligase activity, 0046983=protein dimerization activity, 0008270=zinc ion binding" "0016567=protein ubiquitination, 0048477=oogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0007029=endoplasmic reticulum organization, 0050769=positive regulation of neurogenesis" "0005737=cytoplasm, 0005634=nucleus" "ARI1_DROME, ariadne, AAS65398.1, Ariadne-1, Ariadne, Ari-1, CG5659, l(1)16Fj, ari-1a, ari, HL-V" "IPR031127=E3 ubiquitin ligase RBR family, IPR018957=Zinc finger, C3HC4 RING-type, IPR002867=IBR domain, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG5659 16-Dec-15 2015_12 "ENSDARG00000003616(arih1),ENSDARG00000036870(arih1l)" YKR017C() "WBGene00016158(ari-1),WBGene00016156(C27A12.6),WBGene00016157(C27A12.7),WBGene00013538(tag-349)" ENSMUSG00000025234(Arih1) ENSG00000166233(ARIH1) " embryonic stage -- adult stage , adult stage && oogenesis stage , adult stage | female , adult stage , larval stage " " nurse cell

, gonad

, follicle cell

, adult central nervous system

,

ubiquitous " " embryonic stage -- adult stage , egg stage | unfertilized egg " unfertilized egg

"visible,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,viable,partially lethal - majority die,fertile,lethal - all die before end of pupal stage,some die during pupal stage,poor,lethal,female sterile,germline clone,non-rescuable maternal effect,neuroanatomy defective,somatic clone,neurophysiology defective,flightless,jumping defective,courtship behavior defective,male,locomotor behavior defective" "wing,coxal tergal remotor muscle,mesothoracic extracoxal depressor muscle 66,ovariole,germline cyst,rhabdomere R1,somatic clone,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,photoreceptor cell R1 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R2 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R3 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R4 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R5 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R6 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R7 & rough endoplasmic reticulum | somatic clone,optic lobe,adult brain,thoracico-abdominal ganglion,cervical connective,macrochaeta" DRSC21603 IK 1.063687657 1.596058135 0.029016339 0.002714213 1.508595669 1.122542465 FBgn0028241 l(3)S001620a lethal (3) S001620a http://flybase.net/reports/FBgn0028241.html gene "0016/20, l(3)S001620" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0001202 hook hook http://flybase.net/reports/FBgn0001202.html protein_coding_gene 0008017=microtubule binding "0006909=phagocytosis, 0030705=cytoskeleton-dependent intracellular transport, 0008340=determination of adult lifespan, 0045467=R7 cell development, 0006897=endocytosis, 0016197=endosomal transport" "0005768=endosome, 0005737=cytoplasm, 0045202=synapse" "CG10653, Hook, dHk, hk" IPR008636=Hook-related protein family CG10653 16-Dec-15 2015_12 ENSDARG00000042946(hook1) "ENSXETG00000010213(hook3),ENSXETG00000004765(HOOK2),ENSXETG00000008880(HOOK1)" "ENSMUSG00000037234(Hook3),ENSMUSG00000028572(Hook1),ENSMUSG00000052566(Hook2)" "ENSG00000168172(HOOK3),ENSG00000134709(HOOK1),ENSG00000095066(HOOK2)" embryonic stage -- adult stage "viable,fertile,visible,recessive,wild-type,short lived,male,neurophysiology defective,neuroanatomy defective" "macrochaeta,macrochaeta & head,macrochaeta & thorax,ommatidium,multivesicular body,lysosome,endosome,synapse,bouton,supernumerary,glial cell,eye disc" DRSC03545 K -0.376992752 -0.102187248 0.066822142 0.431928205 0.251338682 -1.565422544 FBgn0000068 alo alopecia http://flybase.net/reports/FBgn0000068.html gene 16-Dec-15 2015_12 "viable,good,male,female,reduced,male fertile,female fertile,visible,recessive,fertile" microchaeta & adult abdomen FBgn0036927 CG7433 http://flybase.net/reports/FBgn0036927.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0003867=4-aminobutyrate transaminase activity" "0009448=gamma-aminobutyric acid metabolic process, 0006520=cellular amino acid metabolic process" "0005759=mitochondrial matrix, 0005739=mitochondrion" 149085_at "IPR015424=Pyridoxal phosphate-dependent transferase, IPR004631=4-aminobutyrate aminotransferase, eukaryotic, IPR005814=Aminotransferase class-III, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2" CG7433 16-Dec-15 2015_12 ENSDARG00000006031(abat) YGR019W(UGA1) WBGene00001794(gta-1) ENSXETG00000008691(ABAT) ENSMUSG00000057880 ENSG00000183044(ABAT) "viable,fertile" FBgn0026432 Grip163 Grip163 http://flybase.net/reports/FBgn0026432.html FBgn0036238 protein_coding_gene 0043015=gamma-tubulin binding "0051298=centrosome duplication, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division" "0005813=centrosome, 0000922=spindle pole, 0008274=gamma-tubulin ring complex" "Dgrips163, DGrip163, GCP6, CG5688, grip163, Dgrip163" IPR007259=Gamma-tubulin complex component protein CG5688 16-Dec-15 2015_12 ENSDARG00000005553 ENSXETG00000022264(TUBGCP6) ENSMUSG00000033790(Tubgcp5) ENSG00000153575(TUBGCP5) "lethal,viable,mitotic cell cycle defective,partially lethal - majority live,female sterile" "S2 cell-line,spindle,adult external abdomen" FBgn0052036 CG32036 http://flybase.net/reports/FBgn0052036.html FBgn0036006 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG3426 IPR002557=Chitin binding domain CG32036 16-Dec-15 2015_12 "viable,fertile" DRSC10362 E 0.172613795 -0.355815965 2.113244976 0.378479261 0.485455217 0.4156102 FBgn0017561 Ork1 Open rectifier K+ channel 1 http://flybase.net/reports/FBgn0017561.html "FBgn0046859, FBgn0046860, FBgn0046861" protein_coding_gene "0022841=potassium ion leak channel activity, 0005267=potassium channel activity, 0042803=protein homodimerization activity" "0045475=locomotor rhythm, 0006813=potassium ion transport, 0071805=potassium ion transmembrane transport, 0002027=regulation of heart rate" "0005886=plasma membrane, 0016021=integral component of membrane, 0034705=potassium channel complex" "anon-WO0161006.1, ORK, ORK-1, dOrk, dORK1, dOrk1, open rectifier potassium channel, d-ORK1, ORK1, CG1615, Open rectifier K+ channel 1, anon-WO0161006.22, K[[2P]], DorK, ork1, dORK, anon-WO0161006.23, KCNK0" "IPR003280=Two pore domain potassium channel, IPR013099=Potassium channel domain" CG1615 16-Dec-15 2015_12 "ENSDARG00000062849(LOC563228),ENSDARG00000045956(k2p10.1),ENSDARG00000007151(zgc:123268),ENSDARG00000055123(LOC559728),ENSDARG00000029227" "WBGene00006675(twk-22),WBGene00006674(twk-21)" "ENSXETG00000007210(KCNK4),ENSXETG00000016610(KCNK10),ENSXETG00000023120(KCNK2),ENSXETG00000009961(KCNK5)" ENSMUSG00000023243(Kcnk5) "ENSG00000182450(KCNK4),ENSG00000100433(KCNK10),ENSG00000082482(KCNK2)" " adult stage , embryonic stage && larval stage && adult stage , adult stage && oogenesis stage " " adult muscle system

, adult brain

, ovary

" "neuroanatomy defective,viable,fertile,lethal,locomotor rhythm defective,phototaxis defective,sleep defective,neurophysiology defective,behavior defective,developmental rate defective,small body,visual behavior defective" "embryonic/larval olfactory receptor neuron | first instar larval stage,embryonic/larval heart,projection neuron,Kenyon cell,presynaptic active zoneMz19" FBgn0067647 sd-9 sd-9 http://flybase.net/reports/FBgn0067647.html gene "0042331=phototaxis, 0007270=neuron-neuron synaptic transmission" complementation group 9 16-Dec-15 2015_12 "neurophysiology defective,somatic clone,neuroanatomy defective,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "photoreceptor cell & axon | somatic clone,lamina,somatic clone,medulla,lobula plate,lobula" FBgn0015795 Rab7 Rab7 http://flybase.net/reports/FBgn0015795.html protein_coding_gene "0032403=protein complex binding, 0005525=GTP binding, 0003924=GTPase activity" "0048102=autophagic cell death, 0032510=endosome to lysosome transport via multivesicular body sorting pathway, 0035071=salivary gland cell autophagic cell death, 0008333=endosome to lysosome transport, 0008593=regulation of Notch signaling pathway, 0044130=negative regulation of growth of symbiont in host, 0033227=dsRNA transport, 0016197=endosomal transport, 0032482=Rab protein signal transduction, 0006897=endocytosis, 0016192=vesicle-mediated transport, 1990182=exosomal secretion, 0015031=protein transport, 0048190=wing disc dorsal/ventral pattern formation" "0031982=vesicle, 0031902=late endosome membrane, 0005811=lipid particle, 0005770=late endosome, 0045202=synapse, 0043025=neuronal cell body, 0005886=plasma membrane" "AAF56218, DRab7, RAB7, rab7, Rab-protein 7, DRAB7, DmRab7, dRab7, Rab-r7, CG5915, Drab7, drab7, O76742, Rab-7, Dm Rab7" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG5915 16-Dec-15 2015_12 "ENSDARG00000020497(rab7),ENSDARG00000033654,ENSDARG00000021287(zgc:91909)" YML001W(YPT7) WBGene00004271(rab-7) ENSXETG00000016176(rab7) ENSMUSG00000079477(Rab7) ENSG00000075785(RAB7A) "neuroanatomy defective,lethal - all die before end of pupal stage,recessive,neurophysiology defective,progressive,somatic clone,dominant,viable,fertile,lethal,visible,immune response defective" "dorsal multidendritic neuron ddaC,photoreceptor,progressive,somatic clone,rhabdomere | progressive | somatic clone,synapse | progressive | somatic clone,rhabdomere,synapse,wing,posterior compartment,late endosomeunspecified,glial cell,eye disc,endosomehh-Gal4,endosomeptc-559.1,multivesicular bodyptc-559.1,lysosomeCY2,vesicleeg-Mz360,oocyte,mitochondrial derivativemat.ë±Tub67C.THsimVP16,phagocytic vesicleHml.ëÓ,hemocyte | adult stage" FBgn0023010 l(3)S074205 lethal (3) S074205 http://flybase.net/reports/FBgn0023010.html gene "0742/05, unnamed, 742/5" 16-Dec-15 2015_12 "lethal,recessive,partially lethal - majority die" FBgn0083070 omt omelette http://flybase.net/reports/FBgn0083070.html gene "0007110=meiosis I cytokinesis, 0007111=meiosis II cytokinesis, 0000916=actomyosin contractile ring contraction, 0043147=meiotic spindle stabilization" 16-Dec-15 2015_12 "meiotic cell cycle defective,male,cytokinesis defective,recessive" "spermatid & nucleus | supernumerarye-F1),Nebenkern,spindle & meiotic telophase I | malee-F1),contractile ring & meiotic telophase I | malee-F1),spindle & meiotic telophase II | malee-F1),contractile ring & meiotic telophase II | malee-F1),spermatid & nucleus | supernumerary,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male" FBgn0033096 Zip42C.1 Zinc/iron regulated transporter-related protein 42C.1 http://flybase.net/reports/FBgn0033096.html protein_coding_gene "0005385=zinc ion transmembrane transporter activity, 0046873=metal ion transmembrane transporter activity" "0008344=adult locomotory behavior, 0055069=zinc ion homeostasis, 0008340=determination of adult lifespan, 0071578=zinc II ion transmembrane import" "0016324=apical plasma membrane, 0005622=intracellular, 0016323=basolateral plasma membrane" "Zinc/iron transporter-related protein 1, CG9428, ZIP1, dZIP1, cg9428, Zip1, dZip1, dZip42C.1, Zinc/iron regulated transporter-related protein 1" IPR003689=Zinc/iron permease CG9428 16-Dec-15 2015_12 ENSDARG00000058257(slc39a1) "YLR130C(ZRT2),YGL255W(ZRT1)" "WBGene00018897(F55F8.9),WBGene00017936(F30B5.7),WBGene00014669(C06G8.3),WBGene00013207(Y54G9A.4)" "ENSXETG00000001746(SLC39A2),ENSXETG00000004651(slc39a1),ENSXETG00000019914(TEgg075o04.1),ENSXETG00000003715(SLC39A3)" "ENSMUSG00000052310(Slc39a1),ENSMUSG00000046822(Slc39a3),ENSMUSG00000072572(Slc39a2)" "ENSG00000143570(SLC39A1),ENSG00000141873(SLC39A3)" "visible,conditional,chemical sensitive,lethal - all die during larval stage,chemical resistant,locomotor behavior defective,short lived,viable,melanotic mass phenotype" "eye,conditional,melanotic mass" FBgn0031390 tho2 tho2 http://flybase.net/reports/FBgn0031390.html FBgn0051671 protein_coding_gene "0048477=oogenesis, 0006406=mRNA export from nucleus, 0031990=mRNA export from nucleus in response to heat stress" "0000347=THO complex, 0005634=nucleus" "Tho2, THO2, CG31671, CG4263, macadamia" "IPR021726=THO complex, subunitTHOC2, N-terminal, IPR021418=THO complex, subunitTHOC2, C-terminal" CG31671 16-Dec-15 2015_12 ENSDARG00000037503(thoc2) YNL139C(THO2) WBGene00015813(thoc-2) ENSXETG00000016195(THOC2) ENSMUSG00000037475(Thoc2) ENSG00000125676(THOC2) "viable,fertile,lethal,cell polarity defective,germline clone,visible,somatic clone,female fertile" "egg chamber,germline clone,oocyte,centrosome | germline clone,macrochaeta,somatic clone,mesothoracic tergum" DRSC00646 I 2.327689702 1.046641532 -0.14126571 1.034547605 -0.536008577 1.457503326 FBgn0060831 l(3)S050116b lethal (3) S050116b http://flybase.net/reports/FBgn0060831.html gene "l(3)S050116, 0501/16" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0261870 pky pokey http://flybase.net/reports/FBgn0261870.html gene 16-Dec-15 2015_12 "behavior defective,recessive,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015993 l(2)k06712 lethal (2) k06712 http://flybase.net/reports/FBgn0015993.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system" FBgn0004098 l(2)60Df lethal (2) 60Df http://flybase.net/reports/FBgn0004098.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0041097 robo3 roundabout 3 http://flybase.net/reports/FBgn0041097.html "FBgn0031328, FBgn0031330" protein_coding_gene 0008046=axon guidance receptor activity "0007411=axon guidance, 0008038=neuron recognition, 0008406=gonad development, 0007419=ventral cord development, 0048036=central complex development, 0016319=mushroom body development" "0005886=plasma membrane, 0030424=axon" "ROBO3, CG5423, Robo 3, CG14345, robo3, CT17158, Robo3, Roundabout 3, Robo-3, roundabout 3, dRobo-3" "IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG5423 16-Dec-15 2015_12 embryonic stage | stage 13-15 embryonic central nervous system

"neuroanatomy defective,viable,somatic clone,partially lethal - majority die,recessive,male,neurophysiology defective,partially,fertile" "photoreceptor cell R8,medulla,somatic clone,eye photoreceptor cell,olfactory neuron & antennal lobeSG18.1,olfactory neuron & antennal lobelz-gal4,antennal lobe glomerulus,ectopic,embryonic/larval neuron,ventral nerve cord commissure,VL fascicle,dendritic arborizing neuron,lateral multidendritic neuron ldaA,longitudinal connective,intermediate longitudinal fascicle,medial longitudinal fascicle,interface glial cell,chordotonal organ & embryo & nerve terminal,antennal lobe glomerulus DM2,olfactory neuron & antennal lobe | somatic clone,ellipsoid body,mushroom body gamma-lobe,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,gonad,germline cell,prothoracic leg taste bristle chemosensory neuron,male,eye,giant fiber neuron,abdominal basiconical sensillum dbd & embryo & nerve terminal12.1" DRSC00684 I 1.744209997 -0.130005281 0.003825148 -0.593864269 -0.362651588 -0.359816461 FBgn0010575 sbb scribbler http://flybase.net/reports/FBgn0010575.html "FBgn0034320, FBgn0041106, FBgn0050117" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003714=transcription corepressor activity, 0046872=metal ion binding" "0042461=photoreceptor cell development, 0007412=axon target recognition, 0045570=regulation of imaginal disc growth, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0008345=larval locomotory behavior, 0007476=imaginal disc-derived wing morphogenesis, 0007411=axon guidance, 0045879=negative regulation of smoothened signaling pathway, 0048190=wing disc dorsal/ventral pattern formation" 0005634=nucleus "mtv, bks, l(2)04440, sbb/mtv, brakeless, disc6, Scribbler, Bks, GM04742, Sbb, Brakeless, Group IIa, master of thickveins, CG5580, mother of thick-vein, Master of thickveins" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG5580 16-Dec-15 2015_12 "ENSXETG00000010257(ZNF608),ENSXETG00000010648()" "ENSMUSG00000040524(Zfp609),ENSMUSG00000052713(Zfp608)" "ENSG00000168916(ZNF608),ENSG00000180357(ZNF609)" " adult stage , larval stage&&pupal stage&&adult stage , larval stage && pupal stage && adult stage , larval stage , embryonic stage | early , embryonic stage , larval stage && pupal stage " " abdomen

, thorax

, eye disc | ubiquitous

, ring gland

,

ubiquitous , larval central nervous system

, ventral nerve cord | medial

, ventral thoracic disc

, head

, eye-antennal disc

, embryonic central nervous system

, larval optic lobe

, dorsal mesothoracic disc

, larval brain

" " larval stage , larval stage | third instar " " eye disc | ubiquitous

, morphogenetic furrow | posterior to

, eye disc

, morphogenetic furrow | anterior to

, photoreceptor cell

" "viable,lethal,recessive,visible,dominant,fertile,stress response defective,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,behavior defective,wild-type,somatic clone,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,denticle belt,maternal effect,intersegmental nerve,anterior fascicle & synapse | supernumerary,macrochaeta,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,lamina plexus,photoreceptor cell R1 & neuron,photoreceptor cell R2 & neuron,photoreceptor cell R3 & neuron,photoreceptor cell R4 & neuron,photoreceptor cell R5 & neuron,photoreceptor cell R6 & neuron,wing vein L5,photoreceptor cell R1 & neuron | somatic clone,photoreceptor cell R2 & neuron | somatic clone,photoreceptor cell R3 & neuron | somatic clone,photoreceptor cell R4 & neuron | somatic clone,photoreceptor cell R5 & neuron | somatic clone,photoreceptor cell R6 & neuron | somatic clone,somatic clone,wing vein,ectopic,triple row,double row,wing vein L3,wing vein L4,unguis,arista,antennal segment 3 sensillum,sensillum trichodeum of antennal segment 3,ocellar triangle,trichome of the posterior wing margin,embryonic abdominal segment,rescuable maternal effect,wing margin,ocellus,interocellar bristle,ocellar bristle,photoreceptor cell R1 & axon | somatic clone, with sbbA.GMR.THsapMYC,photoreceptor cell R2 & axon | somatic clone, with sbbA.GMR.THsapMYC,photoreceptor cell R3 & axon | somatic clone, with sbbA.GMR.THsapMYC,photoreceptor cell R4 & axon | somatic clone, with sbbA.GMR.THsapMYC,photoreceptor cell R5 & axon | somatic clone, with sbbA.GMR.THsapMYC,photoreceptor cell R6 & axon | somatic clone, with sbbA.GMR.THsapMYC,photoreceptor cell R7,photoreceptor cell & axon | somatic clone,photoreceptor cell R1 & axon | somatic clone, with sbb1,photoreceptor cell R2 & axon | somatic clone, with sbb1,photoreceptor cell R3 & axon | somatic clone, with sbb1,photoreceptor cell R4 & axon | somatic clone, with sbb1,photoreceptor cell R5 & axon | somatic clone, with sbb1,photoreceptor cell R6 & axon | somatic clone, with sbb1,photoreceptor cell R1 & axon | somatic clone, with sbb2,photoreceptor cell R2 & axon | somatic clone, with sbb2,photoreceptor cell R3 & axon | somatic clone, with sbb2,photoreceptor cell R4 & axon | somatic clone, with sbb2,photoreceptor cell R5 & axon | somatic clone, with sbb2,photoreceptor cell R6 & axon | somatic clone, with sbb2,haltere disc,leg,posterior compartment" DRSC05723 IE 1.508348941 -0.006327346 0.272014744 1.543460602 -0.872873362 -1.149669912 FBgn0039346 CG5079 http://flybase.net/reports/FBgn0039346.html protein_coding_gene CG5079 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027289 l(1)G0164 lethal (1) G0164 http://flybase.net/reports/FBgn0027289.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037613 Cks85A Cyclin-dependent kinase subunit 85A http://flybase.net/reports/FBgn0037613.html FBgn0063209 protein_coding_gene 0016538=cyclin-dependent protein serine/threonine kinase regulator activity "0007067=mitotic nuclear division, 0000278=mitotic cell cycle, 0007113=endomitotic cell cycle" 0019005=SCF ubiquitin ligase complex "BcDNA:GM01344, CG9790, Cks, cks85A" "IPR000789=Cyclin-dependent kinase, regulatory subunit" CG9790 16-Dec-15 2015_12 YBR135W(CKS1) WBGene00001051(cks-1) "developmental rate defective,endomitotic cell cycle defective,mitotic cell cycle defective,heat sensitive,increased cell death,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,visible,viable" "embryonic/larval salivary gland,embryonic/larval brain,eye disc,heat sensitive,wing disc,wing hair,trichogen cell" FBgn0002427 l(3)F31 lethal (3) F31 http://flybase.net/reports/FBgn0002427.html gene l(3)31 16-Dec-15 2015_12 "cell lethal,cell autonomous,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone,wing hair,abdomen,abdomen & macrochaeta | somatic clone" FBgn0000751 fs(1)A383 female sterile (1) A383 http://flybase.net/reports/FBgn0000751.html gene fs(1)1162 16-Dec-15 2015_12 "female sterile,recessive,lethal,non-rescuable maternal effect,mitotic cell cycle defective" "blastoderm embryo,embryo" FBgn0004379 Klp67A Kinesin-like protein at 67A http://flybase.net/reports/FBgn0004379.html "FBgn0044647, FBgn0046473, FBgn0060914" protein_coding_gene "0005524=ATP binding, 0003774=motor activity, 0003777=microtubule motor activity, 0008017=microtubule binding" "0007110=meiosis I cytokinesis, 0007052=mitotic spindle organization, 0051225=spindle assembly, 0007019=microtubule depolymerization, 0016346=male meiotic chromosome movement towards spindle pole, 0007018=microtubule-based movement, 0090307=mitotic spindle assembly, 0031134=sister chromatid biorientation, 0055047=generative cell mitosis, 0007100=mitotic centrosome separation, 0051231=spindle elongation, 0007060=male meiosis chromosome segregation, 0007059=chromosome segregation, 0007054=spindle assembly involved in male meiosis I, 0007141=male meiosis I" "0072686=mitotic spindle, 0005876=spindle microtubule, 0005737=cytoplasm, 1990023=mitotic spindle midzone, 0005828=kinetochore microtubule, 0005634=nucleus, 0005871=kinesin complex, 0000776=kinetochore, 0005875=microtubule associated complex" "l(3)S042705, Klp3, Kin-8, anon-WO0140519.224, Kinesin 8, KIF 18A, kinesin-8, KRP67A, DmKlp67A, CG10923, 0427/05, KLP67A, lethal (3) S042705, KLP3, kinesin like protein 67a, KIF18A/B, Klp67, anon-WO0172774.120, Kinesin-8, klp67A" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001752=Kinesin motor domain, IPR027640=Kinesin-like protein" CG10923 16-Dec-15 2015_12 ENSDARG00000008022(zgc:55995) YGL216W(KIP3) "ENSXETG00000004282(KIF18A),ENSXETG00000021253(KIF18B)" ENSMUSG00000027115(Kif18a) ENSG00000121621(KIF18A) " adult stage | male , adult stage | female , embryonic stage && larval stage && pupal stage " " testis

, ovary

" "male sterile,meiotic cell cycle defective,male,mitotic cell cycle defective,cytokinesis defective,female semi-sterile,fertile,partially lethal - majority die,recessive" "S2 cell-line,cytoplasmic microtubule,meiosis I | male29A6),meiosis II | male29A6),spermatocyte & aster | ectopic29A6),spermatocyte & astral microtubule29A6),spermatocyte & spindle | supernumerary29A6),spermatocyte & contractile ring29A6),spermatid & Nebenkern29A6),spermatid & nucleus29A6),spermatocyte & centrosome | supernumerary29A6),spermatocyte & condensed nuclear chromosome29A6),centrosome | blastoderm stage | maternal effect29A6),spindle | blastoderm stage | maternal effect29A6),mitotic anaphase B | blastoderm stage | maternal effect29A6),mitotic metaphase | blastoderm stage | maternal effect29A6),spindle microtubule | blastoderm stage | maternal effect29A6),spindle | embryonic stage 429A6),spermatocyte & nuclear chromosome29A6)[-],mitotic prometaphase & nuclear chromosome | male29A6)[-],meiotic anaphase II & condensed nuclear chromosome | male29A6)[-],spermatocyte & nuclear chromosome29A6),mitotic prometaphase & nuclear chromosome | male29A6),meiotic anaphase II & condensed nuclear chromosome | male29A6),spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,spindle" DRSC11205 E 1.197851509 -0.137680852 5.318506803 -2.263573812 0.193512512 -0.245765969 FBgn0000524 dx deltex http://flybase.net/reports/FBgn0000524.html FBgn0026856 protein_coding_gene "0005112=Notch binding, 0061630=ubiquitin protein ligase activity, 0005515=protein binding, 0008270=zinc ion binding" "0008593=regulation of Notch signaling pathway, 0045746=negative regulation of Notch signaling pathway, 0016567=protein ubiquitination, 0016348=imaginal disc-derived leg joint morphogenesis, 0035220=wing disc development, 0007220=Notch receptor processing, 0045747=positive regulation of Notch signaling pathway, 0006897=endocytosis, 0007219=Notch signaling pathway, 0016055=Wnt signaling pathway" 0005737=cytoplasm "DMDELTEX, CG3929, Dx, Deltex" "IPR004170=WWE domain, IPR018123=WWE domain, subgroup, IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG3929 16-Dec-15 2015_12 "ENSXETG00000016413(DTX1),ENSXETG00000008968(dtx2),ENSXETG00000011970(DTX4)" "ENSMUSG00000039982(Dtx4),ENSMUSG00000029603(Dtx1),ENSMUSG00000004947(Dtx2)" "ENSG00000135144(DTX1),ENSG00000110042(DTX4),ENSG00000091073(DTX2)" " adult stage | female , embryonic stage--pupal stage , embryonic stage | early " "visible,viable,fertile,recessive,lethal,maternal effect,flightless,dominant,male sterile,heat sensitive,increased cell number,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "wing vein,wing margin bristle,wing,ommatidium,photoreceptor cell R3,ectopic,photoreceptor cell R4,interocellar bristle,ocellus,eye,microchaeta,macrochaeta,trichogen cell,tormogen cell,socket,thecogen cell,eo neuron,thorax & macrochaeta,distal,ocellar bristle,acrostichal bristle,wing margin,joint,leg,sensory mother cell,anterior crossvein,wing disc,ventral,microchaeta & mesothoracic tergumpnr-MD237" FBgn0022739 btl::Egfr btl::Egfr http://flybase.net/reports/FBgn0022739.html engineered_fusion_gene "lambda-top, lambda-EGFR, EGFR[lambdatop], lambdatop, lambdaTop, lambdaTOP, lambda-DER, unnamed, lambda-TOP, top" 16-Dec-15 2015_12 "visible,increased cell size,somatic clone,decreased cell death,heat sensitive,neuroanatomy defective,homeotic,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell number,neoplasia" "wing,border follicle cell,chorion,wing vein,ectopic,dorsal appendage,egg,anterior,embryonic/first instar larval cuticle,ganglionic branch 1 | embryonic stage,mesothoracic tergum & macrochaeta | ectopic-C253,mitotic cell cycle | somatic clone,photoreceptor cell,somatic clone,wing vein L3,wing vein L4,tarsal segment,pleurum,ommatidium,muscle founder cell | embryonic stage,mesoderm,denticle belt,mesothoracic tergum,mesothoracic pleurum,wing margin & axon tractBx-MS1096,posterior,embryonic abdominal segment,supernumerary,eye disc,heat sensitive,actin filament & follicle cell,optic cartridge,secondary pigment cell,precursor,tertiary pigment cell,eye photoreceptor cell,wing disc,capitellum,wing margin bristle,dorsal branch primordium,embryonic trachea & cortical actin cytoskeletonbtl.PS,maternal effect,adult midgut precursor cell | third instar larval stage,larval inner optic anlage,muscle attachment site,lamellocyte | larval stage,glial cell,supernumerary | third instar larval stage,embryonic/larval brain | third instar larval stage,adult brain" FBgn0003142 Pri Prickly http://flybase.net/reports/FBgn0003142.html gene Pr 16-Dec-15 2015_12 "viable,recessive,reduced,visible,lethal" "macrochaeta,posterior dorsocentral bristle,scutellar bristle" FBgn0025741 PlexA Plexin A http://flybase.net/reports/FBgn0025741.html FBgn0062490 protein_coding_gene "0071889=14-3-3 protein binding, 0017154=semaphorin receptor activity, 0008201=heparin binding, 0005515=protein binding, 0008046=axon guidance receptor activity" "0008045=motor neuron axon guidance, 0016199=axon midline choice point recognition, 2000305=semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance, 0007411=axon guidance, 0097374=sensory neuron axon guidance" 0016020=membrane "PlexA1, D-Plex A, Plexin A, plexA, DPlexA, plexin A, PlexA, Plex1, plex A, plexin-A, CG11081, BcDNA:GM05237, lincRNA.927, PlexinA, plexin, plex" "IPR014756=Immunoglobulin E-set, IPR002909=IPT domain, IPR002165=Plexin repeat, IPR031148=Plexin family, IPR001627=Sema domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR016201=Plexin-like fold, IPR013783=Immunoglobulin-like fold, IPR013548=Plexin, cytoplasmic RasGAP domain, IPR008936=Rho GTPase activation protein" CG11081 16-Dec-15 2015_12 "ENSDARG00000007172(plxna3),ENSDARG00000061275,ENSDARG00000019328(plxna4),ENSDARG00000060372" WBGene00004047(plx-1) "ENSXETG00000018635(PLXNA1),ENSXETG00000011446(PLXNA4),ENSXETG00000017724(PLXNA2)" "ENSMUSG00000026640(Plxna2),ENSMUSG00000029765(Plxna4),ENSMUSG00000030084(Plxna1),ENSMUSG00000031398(Plxna3)" "ENSG00000076356(PLXNA2),ENSG00000221866(PLXNA4),ENSG00000114554(PLXNA1),ENSG00000130827(PLXNA3)" " embryonic stage | early , embryonic stage | stage >=9 , embryonic stage " "

ubiquitous , embryonic central nervous system

, neuron

, myoblast

" "neuroanatomy defective,viable,visible" "eye photoreceptor cell | third instar larval stage,lamina | third instar larval stage,adult olfactory receptor neuron Or33c/85e,adult olfactory receptor neuron Or46a,adult olfactory receptor neuron Or42a,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,longitudinal connective,abdominal segmental nerve,filamentous actin,macrochaeta,wing disc,longitudinal connective | embryonic stage,embryonic/larval central nervous system,intersegmental nerve,transverse nerve,fascicle,ectopic,central nervous system" FBgn0003129 Poxm Pox meso http://flybase.net/reports/FBgn0003129.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007526=larval somatic muscle development, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis" 0005634=nucleus "pox meso, CG9610, Paired box mesodermal, Pox-meso, P29, Pox-m, poxm, Paired box-meso, pox-meso, meso" "IPR001523=Paired domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR009057=Homeodomain-like" CG9610 16-Dec-15 2015_12 "ENSDARG00000008203(zgc:158781),ENSDARG00000053829(pax9)" "ENSXETG00000023497(PAX1),ENSXETG00000002907(PAX9)" "ENSMUSG00000001497(Pax9),ENSMUSG00000037034(Pax1)" "ENSG00000198807(PAX9),ENSG00000125813(PAX1)" embryonic stage mesoderm | restricted

embryonic stage somatic mesoderm

"neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "dorsal multidendritic neuron ddaC,A1-7 ventral oblique muscle 2,A1-7 dorsal transverse muscle 1,embryonic/larval somatic muscle,A2-7 ventral transverse muscle 1,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,A1-7 ventral oblique muscle 1,A1-7 dorsal oblique muscle 3,A1-7 dorsal oblique muscle 4,A1-7 dorsal acute muscle 3,A1-7 lateral oblique muscle 1,A1-7 lateral transverse muscle 4,abdominal lateral adult muscle precursor cell,ectopic,eye,adult head,antenna,dorsal,dorso-lateral,A1-7 dorsal acute muscle 1,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 5,abdominal dorsal adult muscle precursor cell,mesothoracic tergum" FBgn0000085 ano anomogenitals http://flybase.net/reports/FBgn0000085.html gene ang 16-Dec-15 2015_12 "visible,recessive,partially lethal - majority die,male sterile,viable,male,poor" "macrochaeta & head,macrochaeta & thorax,microchaeta & head,microchaeta & thorax,male genitalia,mesothoracic suture,macrochaeta & adult head,macrochaeta & adult thorax,microchaeta & adult thorax,microchaeta & adult abdomen" FBgn0011230 poe purity of essence http://flybase.net/reports/FBgn0011230.html "FBgn0010161, FBgn0011240, FBgn0015532, FBgn0025867, FBgn0031982" protein_coding_gene "0008270=zinc ion binding, 0005516=calmodulin binding" "0007286=spermatid development, 0007291=sperm individualization, 0042066=perineurial glial growth" 0043186=P granule "ms(2)27C, ms(2)5970, male sterile(2)3420, calo, Calossin, pushover, push, ms(2)01659, CG14472, ms(2)3420, POE_DROME, POE, Calo, unnamed, male sterile(2)27C, Purity of Essence, 3420, Poe" "IPR017986=WD40-repeat-containing domain, IPR003126=Zinc finger, UBR-type, IPR025704=E3 ubiquitin ligase, UBR4" CG14472 16-Dec-15 2015_12 ENSDARG00000009549(si:dkey-7c22.2) WBGene00016650(C44E4.1) ENSXETG00000020830() ENSMUSG00000066036(Ubr4) ENSG00000127481(UBR4) adult stage "neuroanatomy defective,male sterile,recessive,viable,behavior defective,meiotic cell cycle defective,female fertile,uncoordinated,neurophysiology defective,body color defective" "synapse,bouton,spermatozoon,primary spermatocyte cyst,intersegmental nerve,anterior fascicle & synapse,surface associated glial cell,cystic bulge,mesothoracic tergum" DRSC03593 E -0.418358187 -1.427905976 -2.684670334 -0.127114069 -1.157997125 0.099671892 FBgn0015589 Apc APC-like http://flybase.net/reports/FBgn0015589.html FBgn0039604 protein_coding_gene "0008017=microtubule binding, 0008013=beta-catenin binding" "0007420=brain development, 0007411=axon guidance, 0031334=positive regulation of protein complex assembly, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0030111=regulation of Wnt signaling pathway, 0035293=chitin-based larval cuticle pattern formation, 0006886=intracellular protein transport, 0021550=medulla oblongata development, 0008258=head involution, 0030951=establishment or maintenance of microtubule cytoskeleton polarity, 0030178=negative regulation of Wnt signaling pathway, 0007447=imaginal disc pattern formation, 0007405=neuroblast proliferation, 0016337=single organismal cell-cell adhesion, 0007017=microtubule-based process, 0030720=oocyte localization involved in germarium-derived egg chamber formation" "0030424=axon, 0005875=microtubule associated complex, 0045177=apical part of cell, 0005737=cytoplasm" "adenomatous polyposis coli, Adenomatous Polyposis Coli, d-APC, D-APC, Dm APC1, Adenomatous polyposis coli, dAPC1, D-APC1, Adenomatous polyposis coli 1, CG1451, dapc1, apc, dApc, apc1, adenomatous polyposis coli 1, Apc1, dAPC, APC-like, apc 1, DAPC, APC, Adenomatous Polyposis Coli protein, APC1" "IPR000225=Armadillo, IPR026818=Adenomatous polyposis coli (APC) family, IPR016024=Armadillo-type fold, IPR009223=Adenomatous polyposis coli protein, cysteine-rich repeat, IPR011989=Armadillo-like helical, IPR009240=Adenomatous polyposis coli protein, 15 residue repeat" CG1451 16-Dec-15 2015_12 ENSXETG00000021501(APC) "ENSMUSG00000005871(Apc),ENSMUSG00000020135(Apc2)" "ENSG00000134982(APC),ENSG00000115266(APC2)" " embryonic stage | stage >13 , embryonic stage | early " " embryonic nervous system

, epidermis

" " embryonic stage | stage >12 , embryonic stage | late , larval stage | third instar " " embryonic nervous system

, neuron

, tendon cell

, ventral nerve cord commissure

, motor neuron

, longitudinal connective

" "increased cell death,viable,lethal,recessive,heat sensitive,cell lethal" "eye photoreceptor cell,hub cell,male germline stem cell,supernumerary,neuron & retina & pupa,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,photoreceptor cell,photoreceptor,male germline stem cell & spindle3450),male germline stem cell & centrosome3450)" FBgn0062590 Mod(var)1602 Mod(var)1602 http://flybase.net/reports/FBgn0062590.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1602 16-Dec-15 2015_12 "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0025637 SkpA SKP1-related A http://flybase.net/reports/FBgn0025637.html "FBgn0026694, FBgn0026706, FBgn0028296, FBgn0040198, FBgn0066818, FBgn0066819, FBgn0066820" protein_coding_gene "0005515=protein binding, 0004842=ubiquitin-protein transferase activity" "0030261=chromosome condensation, 0046627=negative regulation of insulin receptor signaling pathway, 0031647=regulation of protein stability, 0007067=mitotic nuclear division, 0010824=regulation of centrosome duplication, 0045931=positive regulation of mitotic cell cycle, 0022008=neurogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0051298=centrosome duplication, 0046329=negative regulation of JNK cascade, 0007095=mitotic G2 DNA damage checkpoint, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0016322=neuron remodeling, 0042023=DNA endoreduplication, 0043066=negative regulation of apoptotic process" "0005813=centrosome, 0005819=spindle, 0019005=SCF ubiquitin ligase complex, 0005875=microtubule associated complex" "anon-WO03040301.238, EG:115C2.4, dskpA, spkA, anon-WO03040301.234, skpA, SKPA, l(1)G0389, anon-WO03040301.236, dSkpA, dSKP1, dSkp-1, l(1)G0058, Skp, l(1)G0037, l(1)G0109, Skp1, SKP1, SkpA, CG16983, Skp1-related gene A" "IPR001232=S-phase kinase-associated protein 1-like, IPR016072=SKP1 component, dimerisation, IPR016897=S-phase kinase-associated protein 1, IPR011333=POZ domain, IPR016073=SKP1 component, POZ domain" CG16983 16-Dec-15 2015_12 ENSDARG00000003151(skp1) YDR328C(SKP1) "WBGene00004807(skr-1),WBGene00004808(skr-2)" ENSXETG00000016095(SKP1A) ENSMUSG00000036309(Skp1a) ENSG00000113558(SKP1) "neuroanatomy defective,maternal effect,viable,decreased cell death,conditional,radiation resistant,partially,size defective,increased cell death,lethal,recessive,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,fertile,somatic clone,mitotic cell cycle defective,heat sensitive" "NMJ bouton,maternal effect,embryonic/larval neuromuscular junction,prothoracic tarsal segment,joint,dorsal multidendritic neuron ddaC | pupal stage,wing,wing disc,melanotic mass,embryonic/larval digestive system,ganglion mother cell,gamma Kenyon cell,somatic clone,imaginal disc,embryonic/larval central nervous system,centrosome | supernumerary,chromatin,larval fat body & nucleus,larval foregut & nucleus,larval midgut & nucleus,larval hindgut & nucleus,NMJ bouton | larval stage,embryonic/larval neuroblast" DRSC18833 I 2.312574259 2.845588964 0.557065114 0.533257668 -0.76476465 0.833672225 FBgn0037375 kat-60L1 katanin p60-like 1 http://flybase.net/reports/FBgn0037375.html protein_coding_gene "0016887=ATPase activity, 0008017=microtubule binding, 0008568=microtubule-severing ATPase activity, 0005524=ATP binding" "0016322=neuron remodeling, 0051013=microtubule severing, 0007017=microtubule-based process, 0050775=positive regulation of dendrite morphogenesis" "0005874=microtubule, 0008352=katanin complex, 0005875=microtubule associated complex, 0005783=endoplasmic reticulum" "CG1193, DmCG1193, Katanin-p60L1, kat-60L1, katanin p60-like 1" "IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR015415=Vps4 oligomerisation, C-terminal, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR028596=Katanin p60 subunit A1" CG1193 16-Dec-15 2015_12 YER047C(SAP1) WBGene00003183(mei-1) "short lived,viable,stress response defective,heat stress response defective,neuroanatomy defective,visible,fertile" "dendrite,class IV dendritic arborizing neuron,dendrite & dorsal multidendritic neuron ddaC | pupal stageppk.PG,dendriteppk.1.9,dorsal multidendritic neuron ddaC,chaeta,supernumerary,trichogen cell,dendrite & dorsal multidendritic neuron ddaC | pupal stage,microtubule & dorsal multidendritic neuron ddaC | pupal stage,dendrite & dorsal multidendritic neuron ddaC | pupal stageExel6145)" FBgn0011249 dolly-1 double loops of the Y 1 http://flybase.net/reports/FBgn0011249.html gene "0007283=spermatogenesis, 0007286=spermatid development, 0051276=chromosome organization" "P1784, ms(3)03817, male sterile (3) 80, double loops of the Y-1, ms(3)80" 16-Dec-15 2015_12 "male sterile,recessive" "Y chromosome loop,spermatozoon" FBgn0002749 mis misproportioned http://flybase.net/reports/FBgn0002749.html gene 16-Dec-15 2015_12 "visible,recessive,viable,male,female,partially,male fertile,female fertile,reduced,body color defective" "adult abdomen,macrochaeta,microchaeta,male,female,tergite,trichome & adult abdomen | female,wing" FBgn0000442 Pkg21D "Protein kinase, cGMP-dependent at 21D" http://flybase.net/reports/FBgn0000442.html protein_coding_gene "0004692=cGMP-dependent protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0030551=cyclic nucleotide binding" "0006468=protein phosphorylation, 0007526=larval somatic muscle development" 0005737=cytoplasm "PKG, PKG-21D, pkg21D, DG1, PKG 21D, CG3324, cGMP-dependent protein kinase 21D, Pkg1, dg1, cGMP, Dg1" "IPR018488=Cyclic nucleotide-binding, conserved site, IPR011009=Protein kinase-like domain, IPR014710=RmlC-like jelly roll fold, IPR008271=Serine/threonine-protein kinase, active site, IPR018490=Cyclic nucleotide-binding-like, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000595=Cyclic nucleotide-binding domain, IPR017441=Protein kinase, ATP binding site, IPR002374=cGMP-dependent kinase, IPR000719=Protein kinase domain" CG3324 16-Dec-15 2015_12 WBGene00001173(egl-4) "ENSXETG00000021539(PRKG2),ENSXETG00000006462()" embryonic stage -- adult stage "cell migration defective,viable,visible,planar polarity defective" "embryonic/larval salivary gland,A1-7 ventral oblique muscle,mesothoracic tergum,A1-7 ventral acute muscle" FBgn0261868 lkd lackadaisical http://flybase.net/reports/FBgn0261868.html gene 0035177=larval foraging behavior 16-Dec-15 2015_12 "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037420 CG15597 http://flybase.net/reports/FBgn0037420.html protein_coding_gene CG15597 16-Dec-15 2015_12 "viable,fertile,planar polarity defective" DRSC12283 K -0.601711519 0.52267631 -0.333738615 0.245724655 -1.543827833 -1.314560493 FBgn0052150 CG32150 http://flybase.net/reports/FBgn0052150.html "FBgn0036539, FBgn0036540" protein_coding_gene "CG15714, CG12712" IPR029071=Ubiquitin-related domain CG32150 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002561 l(1)sc lethal of scute http://flybase.net/reports/FBgn0002561.html protein_coding_gene "0043565=sequence-specific DNA binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity" "0045893=positive regulation of transcription, DNA-templated, 0061382=Malpighian tubule tip cell differentiation, 0007400=neuroblast fate determination, 0007518=myoblast fate determination, 0007419=ventral cord development, 0006357=regulation of transcription from RNA polymerase II promoter, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0007417=central nervous system development, 0007422=peripheral nervous system development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0022008=neurogenesis" "0005667=transcription factor complex, 0005634=nucleus" "l-sc, ascT3, Lethal-scute, lsc, l'sc, Lethal of Scute, l(1)1Ba, lethal of Scute, CG3839, ASC-T3, T3, L'Sc, L(1)sc, EG:198A6.2, sc/T3, bHLHc28, l[1]sc, AS-C T3, Lethal of scute, lethal at scute, Lethal(1)scute, L'sc, AS-T3" "IPR015660=Achaete-scute transcription factor-related, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG3839 16-Dec-15 2015_12 "ENSDARG00000038386(ascl1a),ENSDARG00000009702(ascl1b)" WBGene00001958(hlh-14) "ENSMUSG00000020052(Ascl1),ENSMUSG00000009248(Ascl2)" "ENSG00000139352(ASCL1),ENSG00000183734(ASCL2)" " embryonic stage , embryonic stage | early , embryonic stage | stage 11,12 " " organism | pair rule

, posterior embryonic/larval midgut

, procephalic segment

, procephalic neuroblast

, optic lobe

, procephalic neurogenic region

, embryonic peripheral nervous system

,

ubiquitous , ventral midline

, epidermoblast

, Malpighian tubule

, labral segment

, embryonic stomatogastric nervous system

, embryonic ganglion mother cell

, neurogenic region

, neuroblast

, cephalic furrow

, stomodeum

, larval optic lobe | presumptive

, central nervous system

, ectoderm

" " embryonic stage , embryonic stage | stage 8-11 , embryonic stage | stage 9-11 , embryonic stage | stage >8 " " epidermoblast

{ + Dl* } , procephalic neurogenic region | restricted

, procephalic neuroblast | subset

, epidermoblast

, deuterocerebral neuroblast | subset

, neuroblast

{ + N* } , tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

" "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal,neuroanatomy defective" "embryonic cardioblast,macrochaeta,microchaeta,sense organ,embryonic/larval somatic muscle,macrochaeta & scutellum455.2,scutellar bristle,ectopic,macrochaeta & abdominal sternite 1-537.4,macrochaeta & abdominal sternite 2-537.4,macrochaeta & abdominal sternite 3-537.4,macrochaeta & abdominal sternite 4-537.4,macrochaeta & abdominal sternite 5-537.4,macrochaeta & abdominal sternite 6-537.4,macrochaeta & pronotumh-540.3,macrochaeta & scutumh-540.3,macrochaeta & metathoracic laterotergiteh-540.3,macrochaeta & mesothoracic laterotergiteh-540.3,microchaeta & pronotumh-540.3,microchaeta & scutumh-540.3,microchaeta & metathoracic laterotergiteh-540.3,microchaeta & mesothoracic laterotergiteh-540.3,wing vein,macrochaeta & wing564.2,scutellum & microchaetaptc-559.1,sensory mother cell & dorsal mesothoracic dip-md544,embryonic/larval maxillary chordotonal organ with two scolopidia,monoscolopidial chordotonal organ,lateral ventral neurectoderm,medial ventral neurectoderm,intermediate ventral neurectoderm,stage 1 neuroblast,ganglion mother cell" FBgn0000273 Pka-C1 "Protein kinase, cAMP-dependent, catalytic subunit 1" http://flybase.net/reports/FBgn0000273.html "FBgn0000353, FBgn0010695" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004691=cAMP-dependent protein kinase activity" "0007228=positive regulation of hh target transcription factor activity, 0045879=negative regulation of smoothened signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0042981=regulation of apoptotic process, 0007611=learning or memory, 0007622=rhythmic behavior, 0050804=regulation of synaptic transmission, 0008359=regulation of bicoid mRNA localization, 0008355=olfactory learning, 0007615=anesthesia-resistant memory, 0007480=imaginal disc-derived leg morphogenesis, 0007448=anterior/posterior pattern specification, imaginal disc, 0007317=regulation of pole plasm oskar mRNA localization, 0048749=compound eye development, 0007613=memory, 0007612=learning, 0008103=oocyte microtubule cytoskeleton polarization, 0048477=oogenesis, 0040040=thermosensory behavior, 0019933=cAMP-mediated signaling, 0006468=protein phosphorylation, 0045475=locomotor rhythm, 0045187=regulation of circadian sleep/wake cycle, sleep, 0007314=oocyte anterior/posterior axis specification, 0048149=behavioral response to ethanol" "0005886=plasma membrane, 0030425=dendrite, 0005737=cytoplasm, 0005952=cAMP-dependent protein kinase complex, 0044297=cell body" "DCO, l(2)s4402, Protein Kinase A, catalytic subunit of cAMP-dependent protein kinase, Cos-1, Pka-C, CdkA, pkA, dPKA, PKAC1, PKAcA, Protein kinase A, C, costal-1, l(2)01272, pka, Cos, CG4379, cos1, cAMP-dependent protein kinase, Costal-1, Dco, pka-c1, PkaC1, Pka, PKA CI, Dc0, pka-C1, unnamed, PKA-C1, l(2)cos[[1]], pka C1, pKA, cAMP-dependent protein kinase 1, 6353, Cos1, DC0, PKA catalytic subunit, protein kinase A, PKA Cl, dcO, dco, catalytic subunit of PKA, PKAc, PKA, Dcpk, Costal" "IPR017441=Protein kinase, ATP binding site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG4379 16-Dec-15 2015_12 "ENSDARG00000059125(prkacbb),ENSDARG00000016809(prkacab),ENSDARG00000014134(prkacaa),ENSDARG00000001782(prkacba)" "YPL203W(TPK2),YKL166C(TPK3),YJL164C(TPK1)" WBGene00002189(kin-1) ENSXETG00000008649(prkaca) "ENSMUSG00000005469(Prkaca),ENSMUSG00000005034(Prkacb)" "ENSG00000072062(PRKACA),ENSG00000142875(PRKACB),ENSG00000165059(PRKACG)" " adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage " " optic lobe

, mushroom body

, germarium

, oocyte

, adult brain

, thoracico-abdominal ganglion

, nurse cell

" " adult stage | female , adult stage , larval stage | third instar , embryonic stage -- adult stage , adult stage | male " " ovary

, mushroom body beta-lobe

, larval brain

, mushroom body alpha-lobe

, mushroom body

, mushroom body gamma-lobe

, calyx of mushroom body

, testis

, dorsal mesothoracic disc

, male accessory gland

" "lethal,recessive,wild-type,locomotor rhythm defective,viable,visible,circadian rhythm defective,behavior defective,thermotaxis behavior defective,planar polarity defective,somatic clone,female sterile,partially lethal - majority die,cell non-autonomous,chemical sensitive,dominant,memory defective,lethal - all die before end of embryonic stage,germline clone,some die during embryonic stage,partially lethal - majority live,heat sensitive,cold sensitive,temperature conditional,lethal - all die before end of P-stage,decreased cell death,neurophysiology defective,lethal - all die during third instar larval stage,smell perception defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,fertile,tumorigenic,developmental rate defective,partially" "wing,anterior compartment,scutum,leg,Malpighian tubule,eye disc,somatic clone,eye equator,ectopic,ommatidium,morphogenetic furrow,egg,eye,eye-antennal disc,cell non-autonomous,follicle cell,border follicle cell,polar follicle cell,egg chamber,germline clone,nurse cell,oocyte,germline cell,oocyte & microtubule | germ-line clone,microtubule organizing center | germline clone,sex comb,haltere,antenna,adult abdomen & cuticle | anterior compartment,adult abdomen & macrochaeta | anterior compartment,adult abdomen & microchaeta | anterior compartment,eye photoreceptor cell,mesothoracic tergum & macrochaeta | somatic clone | cell non-autonomous,macrochaeta,neuromuscular junction,neuron,female gonopod,gonopod thorn bristle,epiproct,hypoproct,spermathecum,genital arch,lateral plate,clasper,penis,anal plate,wing disc,wing vein L3,adult thorax,mesothoracic tergum,anterior,wing vein,melanotic mass,adult,wing margin bristle" DRSC03399 I -0.280794596 -2.390903532 0.083802859 -0.221914834 -0.923124491 0.056834023 FBgn0035142 Hipk Homeodomain interacting protein kinase http://flybase.net/reports/FBgn0035142.html protein_coding_gene "0004672=protein kinase activity, 0008013=beta-catenin binding, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0008134=transcription factor binding" "0006468=protein phosphorylation, 0043067=regulation of programmed cell death, 0008587=imaginal disc-derived wing margin morphogenesis, 0048749=compound eye development, 0035265=organ growth, 0042332=gravitaxis, 0008586=imaginal disc-derived wing vein morphogenesis, 0045747=positive regulation of Notch signaling pathway, 0010628=positive regulation of gene expression, 0035332=positive regulation of hippo signaling, 0030177=positive regulation of Wnt signaling pathway, 0050821=protein stabilization" 0005634=nucleus "dhipk2, Homeodomain interacting protein kinase, Hipk, Homeodomain-interacting protein kinase 2, homeodomain interactin protein kinase, HIPK, CG17090, HIPK2, Homeodomain-interacting protein kinase, homeodomain-interacting protein kinase, homeodomain interacting protein kinase, hipk" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG17090 16-Dec-15 2015_12 "ENSDARG00000063594,ENSDARG00000042518(hipk2)" WBGene00001994(hpk-1) "ENSXETG00000001698(hipk1),ENSXETG00000014419(HIPK2)" "ENSMUSG00000061436(Hipk2),ENSMUSG00000008730(Hipk1),ENSMUSG00000027177(Hipk3)" "ENSG00000064393(HIPK2),ENSG00000163349(HIPK1),ENSG00000110422(HIPK3)" "gravitaxis defective,visible,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,size defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,fertile,female sterile,cell death defective,somatic clone,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage" "eye,ectopic,ventral,eye photoreceptor cell,somatic clone,wing vein L2,posterior crossvein,wing margin,eye disc,ventral wing blade,wing disc | third instar larval stage,wing vein,intersegmental nerve,wing,imaginal disc epithelial cell,central nervous system,ommatidium" FBgn0036144 GlcAT-P GlcAT-P http://flybase.net/reports/FBgn0036144.html protein_coding_gene "0046987=N-acetyllactosamine beta-1,3-glucuronosyltransferase activity, 0046988=asioloorosomucoid beta-1,3-glucuronosyltransferase activity, 0015020=glucuronosyltransferase activity, 0046989=galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity, 0015018=galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity" "0030166=proteoglycan biosynthetic process, 0006688=glycosphingolipid biosynthetic process, 0009101=glycoprotein biosynthetic process, 0007422=peripheral nervous system development" 0016020=membrane "DmGlcAT-BSII, CG6207, DGlcAT-P, dGlcAT-BSII" "IPR005027=Glycosyl transferase, family 43, IPR029044=Nucleotide-diphospho-sugar transferases" CG6207 16-Dec-15 2015_12 embryonic stage -- adult stage "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "ventral nerve cord,leg,wing,VUM neuron,embryonic/larval peripheral nervous system,peripheral glial cell" DRSC10604 I -1.582716408 3.612300375 -0.77375302 0.406575206 0.703467433 1.331497757 FBgn0039907 lgs legless http://flybase.net/reports/FBgn0039907.html protein_coding_gene "0001105=RNA polymerase II transcription coactivator activity, 0008013=beta-catenin binding, 0005515=protein binding" "0007367=segment polarity determination, 0008587=imaginal disc-derived wing margin morphogenesis, 0016055=Wnt signaling pathway, 0030111=regulation of Wnt signaling pathway, 0030177=positive regulation of Wnt signaling pathway" 0005634=nucleus "Lgl, legless;, Dm Lgs, Lgs, CG2041, Legless, BCL9" "IPR024670=B-cell lymphoma 9, beta-catenin binding domain" CG2041 16-Dec-15 2015_12 "ENSDARG00000036687(LOC100330966),ENSDARG00000055054(bcl9l)" "ENSXETG00000016298(),ENSXETG00000010069(BCL9L)" "ENSMUSG00000038256(Bcl9),ENSMUSG00000063382(Bcl9l)" "ENSG00000186174(BCL9L),ENSG00000116128(BCL9)" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,recessive,germline clone,segment polarity phenotype,cell lethal,cell autonomous,somatic clone,viable" "mesothoracic tergum,ectopic,wing,sternite,pleurum,leg,antenna,embryonic/first instar larval cuticle,denticle,imaginal disc,maternal effect,wing margin" FBgn0037924 CG14712 http://flybase.net/reports/FBgn0037924.html protein_coding_gene 0022008=neurogenesis CG14712 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC14935 I 2.867307026 0.927766685 0.926790328 -1.294797621 -0.695530517 -1.341958083 FBgn0040292 Pth Pth http://flybase.net/reports/FBgn0040292.html gene 16-Dec-15 2015_12 "visible,dominant" "wing,ectopic,scutum" FBgn0001253 ImpE1 Ecdysone-inducible gene E1 http://flybase.net/reports/FBgn0001253.html "FBgn0035884, FBgn0035885, FBgn0052356, FBgn0062446" protein_coding_gene 0007561=imaginal disc eversion 0019898=extrinsic component of membrane "CG32356, CT22003, Imp-E1, Y1-like, IMP-E1, CT33103, CG7116, BcDNA:RE39082, CG13668" "IPR006149=EB domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat" CG32356 16-Dec-15 2015_12 "viable,fertile,lethal" FBgn0065270 l(2)SH2059 lethal (2) SH2059 http://flybase.net/reports/FBgn0065270.html gene l(2)SH2 2059 16-Dec-15 2015_12 "lethal,recessive" FBgn0011080 l(1)Q36 lethal (1) Q36 http://flybase.net/reports/FBgn0011080.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0040066 wds will die slowly http://flybase.net/reports/FBgn0040066.html "FBgn0001403, FBgn0027252, FBgn0029626" protein_coding_gene 0004402=histone acetyltransferase activity "0016573=histone acetylation, 0051568=histone H3-K4 methylation, 0007095=mitotic G2 DNA damage checkpoint, 0022008=neurogenesis, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0006338=chromatin remodeling" "0005875=microtubule associated complex, 0044666=MLL3/4 complex, 0005671=Ada2/Gcn5/Ada3 transcription activator complex, 0044665=MLL1/2 complex, 0005634=nucleus, 0044545=NSL complex, 0048188=Set1C/COMPASS complex" "zw8, CG17437, l(1)16-94, Will die slowly, Wds, EG:BACR25B3.7, lethal(1)3Ad, l(1)G0251, WD5, l(1)3Ad, zw-8, l(1)zw8, WDS, WDR5" "IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG17437 16-Dec-15 2015_12 ENSDARG00000016903(wdr5) YBR175W(SWD3) WBGene00006474(swd-3.1) ENSXETG00000019588(wdr5) ENSMUSG00000026917(Wdr5) ENSG00000196363(WDR5) "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,cell lethal,germline clone,heat sensitive,female sterile,visible,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg,germline clone,female reproductive system,macrochaeta,posterior vertical bristle,posterior scutellar bristle,wing,wing vein,wing vein L2,wing vein L3,wing vein L5,ovary,ganglion mother cell" DRSC18852 E -1.048100407 0.009038524 0.007493099 -3.005349953 -0.441487964 0.136647376 FBgn0005254 l(3)SG73 lethal (3) SG73 http://flybase.net/reports/FBgn0005254.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0052298 CG32298 http://flybase.net/reports/FBgn0052298.html FBgn0045346 protein_coding_gene NEST:bs10a03 CG32298 16-Dec-15 2015_12 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0031261 nAChRë_3 nicotinic Acetylcholine Receptor ë_3 http://flybase.net/reports/FBgn0031261.html protein_coding_gene 0004889=acetylcholine-activated cation-selective channel activity "0006811=ion transport, 0007271=synaptic transmission, cholinergic" "0005892=acetylcholine-gated channel complex, 0045211=postsynaptic membrane, 0016021=integral component of membrane" "Dbeta3, nAcR-21Beta, nAChR, nAcRbeta-21C, CG11822, nicotinic acetylcholine receptor beta 21C, CT33131" "IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR002394=Nicotinic acetylcholine receptor, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006201=Neurotransmitter-gated ion-channel" CG11822 16-Dec-15 2015_12 viable FBgn0030224 CG12637 http://flybase.net/reports/FBgn0030224.html protein_coding_gene IPR009961=Protein of unknown function DUF1487 CG12637 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0000256 capu cappuccino http://flybase.net/reports/FBgn0000256.html FBgn0031576 protein_coding_gene "0003779=actin binding, 0008017=microtubule binding" "0007015=actin filament organization, 0007316=pole plasm RNA localization, 0045010=actin nucleation, 0030029=actin filament-based process, 0045451=pole plasm oskar mRNA localization, 0007315=pole plasm assembly, 0048477=oogenesis, 0007304=chorion-containing eggshell formation" "0005884=actin filament, 0005938=cell cortex, 0005737=cytoplasm" "Cappuccino, Capu, Cappucino, capp, cappucino, CG3399, CG15420" "IPR001265=Formin homology family, Cappuccino subfamily, IPR015425=Formin, FH2 domain" CG3399 16-Dec-15 2015_12 ENSXETG00000016228(FMN2) "ENSMUSG00000028354(Fmn2),ENSMUSG00000044042(Fmn1)" ENSG00000155816(FMN2) " larval stage | third instar , oogenesis stage , adult stage | female , oogenesis stage | stage S4-9 , adult stage | male , oogenesis stage | stage S4-11 , embryonic stage | 0-24hr , oogenesis stage | stage S1-13 " " germarium region 2a && germarium region 2b && germarium region 3

, ovary

, oocyte

, follicle cell

, nurse cell

" "viable,fertile,female sterile,lethal,maternal effect,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,dorsal/ventral axis specification defective,female semi-sterile" "embryonic abdominal segment,dorsal appendage,pole cell,pole granule,chorion | maternal effect,embryo,maternal effect,embryonic abdomen,egg,egg chamber,follicle cell,blastoderm embryo,germline clone,posterior,stage S8 oocyte,microtubule,filamentous actin | oogenesis stage S9,oocyte,oocyte nucleus,chorion,actin filament,nurse cell ring canal,actin filamentnos.UTR.THsimVP16, capuI706A.UAS.PT.RA.TAvicGFP,nurse follicle cell,filamentous actin | oogenesis stage S9ed1),actin filamentnos.UTR.THsimVP16, capu1" FBgn0036726 QIL1 QIL1 http://flybase.net/reports/FBgn0036726.html protein_coding_gene "1903850=regulation of cristae formation, 0022008=neurogenesis" CG7603 IPR026769=MICOS complex subunit Mic13 CG7603 16-Dec-15 2015_12 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0013510 l(1)VA624 lethal (1) VA624 http://flybase.net/reports/FBgn0013510.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0265174 PIG-V "Phosphatidylinositol glycan anchor biosynthesis, class V ortholog (H. sapiens)" http://flybase.net/reports/FBgn0265174.html FBgn0034171 protein_coding_gene 0000030=mannosyltransferase activity "0051205=protein insertion into membrane, 0045052=protein insertion into ER membrane by GPI attachment sequence, 0042996=regulation of Golgi to plasma membrane protein transport, 0006506=GPI anchor biosynthetic process, 0070863=positive regulation of protein exit from endoplasmic reticulum, 0045313=rhabdomere membrane biogenesis" 0005789=endoplasmic reticulum membrane "gpi-mt2, CG6657, CG44239, GPI mannosyltransferase II" IPR007315=GPI mannosyltransferase 2 CG44239 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,viable,neuroanatomy defective,progressive" "rhabdomere,somatic clone,rhabdomere microvillus | somatic clone,progressive,eye photoreceptor cell" FBgn0028142 l(3)S047418 lethal (3) S047418 http://flybase.net/reports/FBgn0028142.html gene 0474/18 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060734 l(3)S067205b lethal (3) S067205b http://flybase.net/reports/FBgn0060734.html gene 0672/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0037218 aux auxilin http://flybase.net/reports/FBgn0037218.html FBgn0062044 protein_coding_gene "0004672=protein kinase activity, 0005524=ATP binding" "0001745=compound eye morphogenesis, 0006468=protein phosphorylation, 1901215=negative regulation of neuron death, 0007219=Notch signaling pathway, 0016191=synaptic vesicle uncoating, 0007291=sperm individualization" 0005795=Golgi stack "DNAJC6, auxillin, Auxillin/DNAJC6, anon-WO0118547.393, CG1107, GAK, auxilin, Auxilin, Auxillin, dAux, Aux" "IPR029021=Protein-tyrosine phosphatase-like, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR001623=DnaJ domain, IPR014020=Tensin phosphatase, C2 domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR000008=C2 domain" CG1107 16-Dec-15 2015_12 ENSDARG00000039384 ENSXETG00000020390(DNAJC6) "ENSMUSG00000062234(Gak),ENSMUSG00000028528(Dnajc6)" "ENSG00000178950(GAK),ENSG00000116675(DNAJC6)" "female sterile,male sterile,neuroanatomy defective,maternal effect,viable,visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,lethal - all die before end of pupal stage,some die during pupal stage" "wing vein,eye,heat sensitive,ommatidium,outer photoreceptor cell,supernumerary,vibrissae,anterior sternopleural bristle,ectopic,scutellar bristle,notopleural bristle,posterior crossvein,inner photoreceptor cell,ventral nerve cord,maternal effect,presumptive embryonic/larval peripheral nervous system,eye photoreceptor cell,sternopleural bristle,cystic bulge,individualization stage spermatid,male germline stem cell,embryo,epidermis,wing,wing blade,ommatidial precursor cluster,somatic clone" FBgn0019972 Drice Death related ICE-like caspase http://flybase.net/reports/FBgn0019972.html protein_coding_gene "0004197=cysteine-type endopeptidase activity, 1990525=BIR domain binding, 0097200=cysteine-type endopeptidase activity involved in execution phase of apoptosis, 0097153=cysteine-type endopeptidase activity involved in apoptotic process" "0012501=programmed cell death, 0006915=apoptotic process, 0035070=salivary gland histolysis, 0035103=sterol regulatory element binding protein cleavage, 0046668=regulation of retinal cell programmed cell death, 0010165=response to X-ray, 0045476=nurse cell apoptotic process, 0048515=spermatid differentiation, 0010623=developmental programmed cell death, 2001269=positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, 0046672=positive regulation of compound eye retinal cell programmed cell death, 0016322=neuron remodeling" 0005737=cytoplasm "DRICE, DrIce, interleukin-1beta-converting enzyme, ice, Drive, drICE, ICE, drice, caspase-3, caspase 3, Ice, DrICE, Drice, crice, drIce, CG7788" "IPR011600=Peptidase C14, caspase domain, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR015917=Peptidase C14A, caspase precursor p45, core, IPR016129=Peptidase C14, ICE, catalytic subunit p20, active site, IPR002138=Peptidase C14, caspase non-catalytic subunit p10, IPR029030=Caspase-like domain" CG7788 16-Dec-15 2015_12 "ENSDARG00000016228,ENSDARG00000017905(casp3a),ENSDARG00000055045(casp3b)" WBGene00000417(ced-3) "ENSXETG00000016471(casp7),ENSXETG00000001537(CASP3)" "ENSMUSG00000025076(Casp7),ENSMUSG00000031628(Casp3)" "ENSG00000165806(CASP7),ENSG00000164305(CASP3)" " pupal stage , embryonic stage -- adult stage " salivary gland

oogenesis stage | stage S10-12 nurse cell

"partially lethal - majority die,some die during pupal stage,visible,decreased cell death,viable,fertile,cell death defective,neuroanatomy defective,increased cell death,short lived,developmental rate defective,partially,tumorigenic,radiation resistant,drug conditional,male fertile,somatic clone,lethal - all die before end of pupal stage,some die during larval stage,wild-type,semi-sterile,some die during embryonic stage" "eye,eye disc,neuron,peptidergic neuron,ectopic,arista,male genitalia,adult abdomen,wing,retina,midline glial cell,spermatid cyst,somatic clone,wing disc,spermatogonial cyst,male germline cell,dendriteppk.PG,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage" DRSC27804 K -0.320751614 0.434879514 -0.075726339 0.151745721 -0.711337791 1.745874793 FBgn0000504 dsx doublesex http://flybase.net/reports/FBgn0000504.html protein_coding_gene "0005515=protein binding, 0042803=protein homodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0008270=zinc ion binding, 0003729=mRNA binding, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048086=negative regulation of developmental pigmentation, 0045498=sex comb development, 0019102=male somatic sex determination, 0008049=male courtship behavior, 0046660=female sex differentiation, 0007485=imaginal disc-derived male genitalia development, 0035215=genital disc development, 0048071=sex-specific pigmentation, 0007486=imaginal disc-derived female genitalia development, 0045497=female analia development, 0007417=central nervous system development, 0007530=sex determination, 0018993=somatic sex determination, 0006357=regulation of transcription from RNA polymerase II promoter, 0045496=male analia development, 0045892=negative regulation of transcription, DNA-templated, 0035263=genital disc sexually dimorphic development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0019101=female somatic sex determination, 0006355=regulation of transcription, DNA-templated, 0000398=mRNA splicing, via spliceosome, 0007283=spermatogenesis, 0045893=positive regulation of transcription, DNA-templated, 0007483=genital disc morphogenesis, 0007619=courtship behavior, 0045433=male courtship behavior, veined wing generated song production, 0007548=sex differentiation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0046661=male sex differentiation, 0045570=regulation of imaginal disc growth, 0016199=axon midline choice point recognition" 0005634=nucleus "double sex, dsxF, Dsx, Dmdsx, DSX, doublesex, CG11094, Hermaphrodite, ix-62c, Doublesex, Hr, dsxM, intersex-62c" "IPR026607=DMRT/protein doublesex/protein male abnormal 3, IPR014932=Doublesex dimerisation, IPR001275=DM DNA-binding domain" CG11094 16-Dec-15 2015_12 ENSXETG00000015285(DMRT3) ENSMUSG00000024837(Dmrt1) ENSG00000143006(DMRTB1) "sex-determination defective,viable,fertile,male fertile,reduced,female fertile,dominant,female,chemical sensitive,neuroanatomy defective,courtship behavior defective,male,recessive,hyperactive,visible,heat sensitive,lethal,male sterile,partially,sterile,body color defective,female sterile,partially lethal - majority die,some die during pupal stage" "female accessory gland,spermathecum,prothoracic tarsal bristle,gonadal sheath proper primordium,female,female terminalia,female genitalia,female gonopod,prothoracic leg,female analia,anal plate,gonad,genitalia,germline cell,adult fruitless pMP-e (female) neuron,ectopic,genital disc,eye,leg,clasper,heat sensitive,penis,lateral plate,macrochaeta,embryonic/first instar larval cuticle,male analia,ovary,adult abdominal segment 6,male,male genitalia,sex comb,male accessory gland,flight muscle,male limited,testis,egg chamber,somatic clone,hub cell,epiproct,abdominal sternite 6,adult cuticle & abdominal segment 5 | female,adult cuticle & abdominal segment 6 | female,prothoracic leg taste bristle chemosensory neuron,adult abdominal segment 7,terminalia,abdominal tergite 7,serotonergic neuron,female genital disc,mesothoracic tergum" DRSC16934 I 1.921675821 0.1522242 -0.017176227 0.119665101 0.555135033 0.410370857 FBgn0053126 NLaz Neural Lazarillo http://flybase.net/reports/FBgn0053126.html "FBgn0031336, FBgn0063669" protein_coding_gene "0008289=lipid binding, 0031409=pigment binding" "0033500=carbohydrate homeostasis, 0008340=determination of adult lifespan, 0032504=multicellular organism reproduction, 0070328=triglyceride homeostasis, 0006979=response to oxidative stress" 0005615=extracellular space "BcDNA:RE67583, CT33980, DNLaz, Nlaz, CG33126, CG16933, neural Lazarillo" "IPR000566=Lipocalin/cytosolic fatty-acid binding domain, IPR012674=Calycin, IPR022271=Lipocalin, ApoD type, IPR011038=Calycin-like, IPR003057=Invertebrate colouration protein" CG33126 16-Dec-15 2015_12 "ENSDARG00000057437(zgc:123339),ENSDARG00000060345(zgc:153593),ENSDARG00000060350" ENSMUSG00000022548(Apod) ENSG00000189058(APOD) "stress response defective,short lived,starvation stress response defective,chemical sensitive,courtship behavior defective,long lived,viable" FBgn0000108 Appl ë_ amyloid protein precursor-like http://flybase.net/reports/FBgn0000108.html FBgn0028498 protein_coding_gene "0046914=transition metal ion binding, 0005515=protein binding, 0008201=heparin binding" "0007422=peripheral nervous system development, 0007399=nervous system development, 0007614=short-term memory, 0016319=mushroom body development, 0050808=synapse organization, 0007611=learning or memory, 0048678=response to axon injury, 0007616=long-term memory, 0051602=response to electrical stimulus, 0048812=neuron projection morphogenesis, 1901215=negative regulation of neuron death" "0005576=extracellular region, 0005886=plasma membrane" "APP-like, Abeta, appl, APPL, CG7727, BcDNA:GH04413, amyloid precursor protein-like, Amyloid Precursor Protein-like, beta-amyloid-protein-precursor-like, APP, amyloid precursor protein, Amyloid Precursor-Like Protein, Beta amyloid protein precursor-like, beta amyloid protein precursor-like, EG:65F1.5" "IPR008154=Amyloidogenic glycoprotein, extracellular, IPR019543=Beta-amyloid precursor protein C-terminal, IPR019745=Amyloidogenic glycoprotein, intracellular domain, conserved site, IPR024329=Amyloidogenic glycoprotein, E2 domain, IPR015849=Amyloidogenic glycoprotein, heparin-binding, IPR011178=Amyloidogenic glycoprotein, copper-binding, IPR019744=Amyloidogenic glycoprotein, extracellular domain conserved site" CG7727 16-Dec-15 2015_12 "ENSDARG00000055543(appb),ENSDARG00000054864(aplp2),ENSDARG00000059036(appa)" WBGene00000149(apl-1) "ENSXETG00000013612(app),ENSXETG00000014638(APLP2)" "ENSMUSG00000006651(Aplp1),ENSMUSG00000031996(Aplp2)" "ENSG00000142192(APP),ENSG00000084234(APLP2)" " pupal stage && adult stage , embryonic stage , larval stage , larval stage | third instar , embryonic stage -- adult stage , adult stage " " retina

, embryonic central nervous system

, optic lobe

, eye-antennal disc

, larval central nervous system

, central nervous system

, subesophageal ganglion

, peripheral nervous system

, head

" " embryonic stage , pupal stage && adult stage , larval stage , pupal stage&&adult stage , adult stage , pupal stage " " longitudinal connective

, medulla neuropil

, embryonic central nervous system

, ventral nerve cord commissure

, mushroom body

, neuromere &&of larval mesothoracic segment

, lamina

, photoreceptor cell

, ventral nerve cord

, peripheral nervous system

, Kenyon cell

, adult brain

, optic nerve

, larval optic stalk

, thoracico-abdominal ganglion

, lobula

, neuromere &&of larval metathoracic segment

, photoreceptor cell R1--8

, eye-antennal disc

, larval brain

, neuromere &&of larval abdominal segment 8

, lobe system of mushroom body

, neuromere &&of larval prothoracic segment

" "memory defective,neuroanatomy defective,viable,fertile,neurophysiology defective,visual behavior defective,visible,short lived,planar polarity defective,partially lethal - majority die,wild-type,increased cell death,phototaxis defective,progressive" "macrochaeta,bouton,ectopic,scutellar bristle,sternopleural bristle,NMJ bouton,anterior scutellar bristle,posterior scutellar bristle,embryonic/larval nervous system,adult brain,photoreceptor cell,photoreceptor cell R3,mechanosensory sensory organ,trichogen cell,eo neuron,ventral adult lateral neuron & dendritic treeP2.4.Pdf,wing,crossvein,wing vein,wing pouch,cell body rind of lamina,retina" FBgn0011274 Dif Dorsal-related immunity factor http://flybase.net/reports/FBgn0011274.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0005515=protein binding" "0035206=regulation of hemocyte proliferation, 0006952=defense response, 0006974=cellular response to DNA damage stimulus, 0050830=defense response to Gram-positive bacterium, 0048935=peripheral nervous system neuron development, 0006955=immune response, 0002781=antifungal peptide production, 0045087=innate immune response, 0035070=salivary gland histolysis, 0009620=response to fungus, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042387=plasmatocyte differentiation, 0008063=Toll signaling pathway, 0010628=positive regulation of gene expression, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0035171=lamellocyte differentiation, 0006967=positive regulation of antifungal peptide biosynthetic process, 0050832=defense response to fungus" "0005737=cytoplasm, 0005634=nucleus" "6794, CG6794, DIF, Dorsal-related transcription factor, Dorsal related immunity factor, dorsal-related immunity factor, Dorsal-like immunity factor, dif" "IPR030492=Rel homology domain, conserved site, IPR002909=IPT domain, IPR011363=Dorsal/Dif protein, IPR013783=Immunoglobulin-like fold, IPR014756=Immunoglobulin E-set, IPR000451=NF-kappa-B/Dorsal, IPR008967=p53-like transcription factor, DNA-binding, IPR011539=Rel homology domain (RHD), DNA-binding domain" CG6794 16-Dec-15 2015_12 ENSDARG00000055276(rel) "ENSMUSG00000020275(Rel),ENSMUSG00000024927(Rela)" "ENSG00000173039(RELA),ENSG00000162924(REL)" " larval stage , pupal stage , adult stage " larval stage embryonic/larval fat body

"immune response defective,viable,fertile,visible,stress response defective,cold sensitive,dominant,recessive,short lived,conditional,lethal,partially" "macrochaeta,mesothoracic tergum,salivary gland,heat sensitive,ectopic,cold sensitive,dorsocentral bristle,embryonic/larval hemocyte,supernumerary,lamellocyte,plasmatocyte" FBgn0041621 Or82a Odorant receptor 82a http://flybase.net/reports/FBgn0041621.html "FBan0031519, FBgn0051519" protein_coding_gene "0004984=olfactory receptor activity, 0005549=odorant binding" "0032504=multicellular organism reproduction, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0032590=dendrite membrane, 0005615=extracellular space, 0016021=integral component of membrane" "DOR61, 82a, DmOR82A, CG31519" "IPR004117=Olfactory receptor, Drosophila" CG31519 16-Dec-15 2015_12 "smell perception defective,viable" FBgn0002656 mat(2)cell-E maternal effect cellularisation defect E http://flybase.net/reports/FBgn0002656.html gene 0007349=cellularization mat(2)cellQA13 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0065426 l(2)SH1514 lethal (2) SH1514 http://flybase.net/reports/FBgn0065426.html gene l(2)SH2 1514 16-Dec-15 2015_12 "lethal,recessive" FBgn0053644 CG33644 http://flybase.net/reports/FBgn0053644.html protein_coding_gene IPR010512=Protein of unknown function DUF1091 CG33644 16-Dec-15 2015_12 viable FBgn0035608 blanks blanks http://flybase.net/reports/FBgn0035608.html protein_coding_gene 0035197=siRNA binding "0007291=sperm individualization, 0016246=RNA interference, 0031935=regulation of chromatin silencing" "0005634=nucleus, 0005737=cytoplasm" "lump, CG10630" IPR014720=Double-stranded RNA-binding domain CG10630 16-Dec-15 2015_12 "female fertile,male sterile,recessive,lethal,viable" "sperm individualization complex,individualization stage spermatid,spermatozoon,elongation stage spermatid" FBgn0083945 CG34109 http://flybase.net/reports/FBgn0083945.html "FBan0013129, FBgn0032183, FBgn0032185, FBgn0040966" protein_coding_gene 0022008=neurogenesis "CG12441, CG13129, CG13128" IPR005240=Protein of unknown function DUF389 CG34109 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable" ganglion mother cell FBgn0046294 CG12699 http://flybase.net/reports/FBgn0046294.html "FBgn0034207, FBgn0044736, FBgn0045194" protein_coding_gene "bs24f01.y1, NEST:bs24f01, BEST:GH14656, anon-WO0140519.144, GH14656" CG12699 16-Dec-15 2015_12 viable FBgn0032859 Arpc2 "Actin-related protein 2/3 complex, subunit 2" http://flybase.net/reports/FBgn0032859.html FBgn0062209 protein_coding_gene "0003779=actin binding, 0005200=structural constituent of cytoskeleton" "0034314=Arp2/3 complex-mediated actin nucleation, 0030031=cell projection assembly, 0008064=regulation of actin polymerization or depolymerization, 0046331=lateral inhibition, 0000902=cell morphogenesis, 0030866=cortical actin cytoskeleton organization, 0008360=regulation of cell shape" "0070938=contractile ring, 0045179=apical cortex, 0005885=Arp2/3 protein complex" "ARC-P34, ArcP34, ARC-p34, CG10954, Arpc2, p34, Arc-p34, 38C.47, ARPC2, ARPC2/p34, anon-WO0118547.154" IPR007188=Actin-related protein 2/3 complex subunit 2 CG10954 16-Dec-15 2015_12 ENSDARG00000018496(LOC100329800) YNR035C(ARC35) WBGene00021170(arx-4) ENSXETG00000027920(Q6GL82_XENTR) ENSMUSG00000006304(Arpc2) ENSG00000163466(ARPC2) "cell shape defective,visible,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,ommatidium,rhabdomere,chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC02113 I -1.282558552 -1.569719312 0.213656071 -0.452729051 -0.061080942 -0.060350133 FBgn0040348 CG3703 http://flybase.net/reports/FBgn0040348.html FBgn0029548 protein_coding_gene 0048812=neuron projection morphogenesis "BACR7A4.15, EG:BACR7A4.15" IPR004012=RUN domain CG3703 16-Dec-15 2015_12 WBGene00020572(T19D7.4) ENSMUSG00000035007(Rundc1) ENSG00000198863(RUNDC1) "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0011781 l(2)rG270 lethal (2) rG270 http://flybase.net/reports/FBgn0011781.html gene 0048477=oogenesis 16-Dec-15 2015_12 "female sterile,lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone,egg" FBgn0003267 ro rough http://flybase.net/reports/FBgn0003267.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0001012=RNA polymerase II regulatory region DNA binding, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0045464=R8 cell fate specification, 0045680=negative regulation of R8 cell differentiation, 0007460=R8 cell fate commitment, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048749=compound eye development, 0048054=R2/R5 cell differentiation, 0007463=R2/R5 cell fate commitment, 0042067=establishment of ommatidial planar polarity" 0005634=nucleus "Ro, Rough, DROROUGH, CG6348" "IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG6348 16-Dec-15 2015_12 larval stage | third instar " photoreceptor cell R2..5

{ + vehs.sev } , mystery cell

" "planar polarity defective,recessive,visible,heat sensitive,lethal,wild-type,viable,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "photoreceptor cell R3,ectopic,precursor,photoreceptor cell R4,photoreceptor cell R2,photoreceptor cell R5,ommatidium,eye photoreceptor cell,cone cell,eye,heat sensitive,photoreceptor cell R7,cell autonomous,somatic clone,photoreceptor cell R1,photoreceptor cell R6,retina,lens,primary pigment cell,macrochaeta,photoreceptor cell R8,supernumerary,morphogenetic furrow" DRSC17046 IE 0.045058179 -2.522851831 -1.553791393 -2.060778036 0.48289213 -0.650627194 FBgn0026371 SAK Sak kinase http://flybase.net/reports/FBgn0026371.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0046777=protein autophosphorylation, 0007288=sperm axoneme assembly, 0006468=protein phosphorylation, 0051297=centrosome organization, 0035186=syncytial blastoderm mitotic cell cycle, 0051298=centrosome duplication, 0007052=mitotic spindle organization, 0031647=regulation of protein stability, 0045732=positive regulation of protein catabolic process, 0046599=regulation of centriole replication, 0007099=centriole replication, 0007140=male meiosis" 0005814=centriole "Sak, SAK, SAK/PLK4, plk4, Polo-like kinase 4, DmSAK, sak, CG7186, SAK/PLK, PLK4, Sak kinase, Plk4" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain, IPR000959=POLO box duplicated domain" CG7186 16-Dec-15 2015_12 ENSDARG00000004576(plk4) ENSXETG00000022522(PLK4) ENSMUSG00000025758(Plk4) ENSG00000142731(PLK4) "mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,developmental rate defective,male sterile,sterile,meiotic cell cycle defective,lethal,partially,some die during immature adult stage,uncoordinated,recessive,neuroanatomy defective" "embryo,centriolemat.ë±Tub67C.THsimVP16,centrosome,neuroblast,supernumerary,centrosome | supernumerary,centrosome & larval brain,spindle & larval brain,centriole & larval brain,centriole & primary spermatocyte,spindle & primary spermatocyte,centrosome & primary spermatocyte,astral microtubule & primary spermatocyte,spermatid axoneme,spermatid,spermatozoon,centriole,spermatocyte,spindle,primary spermatocyte,presumptive embryonic/larval peripheral nervous system,neuron,longitudinal connective,ventral nerve cord,embryonic/larval brain,centriole | ectopicmat.ë±Tub67C.THsimVP16,centriole | supernumerarymat.ë±Tub67C.THsimVP16" FBgn0031997 PGAP5 Post-GPI attachment to proteins 5 ortholog (H. sapiens) http://flybase.net/reports/FBgn0031997.html protein_coding_gene 0016787=hydrolase activity CG8455 "IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG8455 16-Dec-15 2015_12 ENSDARG00000045416(mppe1) YDR182W(CDC1) WBGene00015238(B0511.13) ENSXETG00000019699(MPPE1) ENSMUSG00000062526(Mppe1) ENSG00000154889(MPPE1) lethal FBgn0003360 sesB stress-sensitive B http://flybase.net/reports/FBgn0003360.html "FBgn0001474, FBgn0001601, FBgn0001665, FBgn0005428, FBgn0005676, FBgn0027300, FBgn0028338, FBgn0040166, FBgn0064129, FBgn0066004" protein_coding_gene "0022857=transmembrane transporter activity, 0005471=ATP:ADP antiporter activity" "0034599=cellular response to oxidative stress, 0001508=action potential, 0051480=cytosolic calcium ion homeostasis, 0008340=determination of adult lifespan, 0015867=ATP transport, 0009612=response to mechanical stimulus, 0048477=oogenesis, 0007629=flight behavior, 0010507=negative regulation of autophagy, 0006839=mitochondrial transport, 0055085=transmembrane transport, 0040011=locomotion, 2001171=positive regulation of ATP biosynthetic process, 0007268=synaptic transmission, 0015866=ADP transport, 0051560=mitochondrial calcium ion homeostasis, 0070050=neuron cellular homeostasis, 0051900=regulation of mitochondrial depolarization, 0051124=synaptic growth at neuromuscular junction, 0046716=muscle cell cellular homeostasis, 0048489=synaptic vesicle transport" "0016021=integral component of membrane, 0005743=mitochondrial inner membrane, 0005739=mitochondrion, 0005811=lipid particle, 0031966=mitochondrial membrane" "A/A-T, unnamed, l(1)9Ed, A/A-T/sesB, CG16944, ANT1, ANT, l(1)G0247, Drosophila ANT, ses B, l(1)S12, l(1)EM31, l(1)DC701, anon-WO02059370.55, Adenine nucleotide translocase, l(1)G0126, stress sensitive B, l(1)G0386, Stress-sensitive B, l(1)9Fa, SesB, ADP,ATP carrier protein, orangi, dANT, adenine nuclear translocase, Hmr, ADP/ATP translocase, EM12, ADT2, lethal(1)9Ed, jive, S12" "IPR002067=Mitochondrial carrier protein, IPR002113=Adenine nucleotide translocator 1, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG16944 16-Dec-15 2015_12 "ENSDARG00000027355(slc25a4),ENSDARG00000005853(slc25a6),ENSDARG00000071483,ENSDARG00000071480(slc25a5),ENSDARG00000042521(si:dkey-251i10.1)" "YBL030C(PET9),YBR085W(AAC3),YMR056C(AAC1)" "WBGene00020140(ant-1.4),WBGene00010485(ant-1.3),WBGene00006439(ant-1.1),WBGene00007057(ant-1.2)" "ENSXETG00000025740(slc25a4),ENSXETG00000025466(slc25a5)" "ENSMUSG00000016319(Slc25a5),ENSMUSG00000031633(Slc25a4),ENSMUSG00000067161(Gm5560)" "ENSG00000005022(SLC25A5),ENSG00000169100(SLC25A6),ENSG00000151729(SLC25A4)" " embryonic stage | mid-late , adult stage " "paralytic,conditional,neuroanatomy defective,neurophysiology defective,lethal,recessive,viable,fertile,male,oxidative stress response defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,partially lethal - majority die,heat sensitive,flightless,female,reduced,cold sensitive,female sterile,short lived,locomotor behavior defective,bang sensitive,hypoactive,developmental rate defective,auditory perception defective,courtship behavior defective,male limited,majority die during embryonic stage,maternal effect,lethal - all die before end of larval stage,some die during larval stage,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,behavior defective,lethal - all die before end of P-stage,some die during pharate adult stage" "NMJ bouton,supernumerary,ovariole,germline clone,eye,somatic clone,embryonic/larval Malpighian tubule,mitochondrion | larval stagec42,mitochondrion | larval stagec710,mitochondrion | larval stageUro.PT,mitochondrion | larval stagehs.PB,thoracico-abdominal ganglion,flight muscle,neuromuscular junction,Malpighian tubule,mitochondrion,egg chamber,maternal effect,trichogen cell,mesothoracic tergum" DRSC20371 E -0.27849747 -0.003666531 -2.499123017 0.120338607 -1.147290991 -0.47908395 FBgn0043001 Chrac-16 Chromatin accessibility complex 16kD protein http://flybase.net/reports/FBgn0043001.html "FBgn0030363, FBgn0040209, FBgn0062993" protein_coding_gene "0046982=protein heterodimerization activity, 0043565=sequence-specific DNA binding, 0070615=nucleosome-dependent ATPase activity" "0042766=nucleosome mobilization, 0006974=cellular response to DNA damage stimulus" 0008623=CHRAC "CHRAC-16, CHRAC, joey, Chrac16, CG15736, BcDNA:RE59557, Chrac-16, 15736, 20K protein, CHRAC16" "IPR003958=Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072=Histone-fold" CG15736 16-Dec-15 2015_12 ENSDARG00000042337(zgc:110753) WBGene00013150(Y53F4B.3) ENSMUSG00000068391(Chrac1) ENSG00000104472(CHRAC1) viable DRSC20343 E 1.03258003 0.781101856 6.631703228 -0.2884066 -0.31536503 0.5793855 FBgn0013997 Nrx-IV Neurexin IV http://flybase.net/reports/FBgn0013997.html FBgn0002261 protein_coding_gene 0004888=transmembrane signaling receptor activity "0008366=axon ensheathment, 0008104=protein localization, 0061343=cell adhesion involved in heart morphogenesis, 0008065=establishment of blood-nerve barrier, 0016080=synaptic vesicle targeting, 0019991=septate junction assembly, 0016081=synaptic vesicle docking, 0045216=cell-cell junction organization, 0003015=heart process, 0007391=dorsal closure, 0008039=synaptic target recognition, 0060857=establishment of glial blood-brain barrier, 0035151=regulation of tube size, open tracheal system, 0007163=establishment or maintenance of cell polarity, 0021682=nerve maturation" "0005919=pleated septate junction, 0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005918=septate junction, 0005886=plasma membrane" "neurexin IV, NRX, Nrx, Neurexin IV, Dnrx, l(3)68Ff, Neurexin-4, CG682, Neurexin 4, Neurexin-IV, rose-gespleten region interval 23, neurexin, Neurexin, NeurexinIV, CT21123, NRX IV, nrx-IV, rsg23, Nx IV, Nrx IV, CG6827, neurexinIV, l(3)rsg23, nrxIV, NrxIV, nrx IV, nrx" "IPR008979=Galactose-binding domain-like, IPR003585=Neurexin/syndecan/glycophorin C, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000421=Coagulation factor 5/8 C-terminal domain, IPR000742=EGF-like domain" CG6827 16-Dec-15 2015_12 WBGene00003772(nlr-1) "ENSXETG00000010874(),ENSXETG00000020201(CNTNAP1)" "ENSMUSG00000039419(Cntnap2),ENSMUSG00000070695(Cntnap5a),ENSMUSG00000038048(Cntnap5c),ENSMUSG00000031772(Cntnap4),ENSMUSG00000067028(Cntnap5b),ENSMUSG00000033063(Cntnap3),ENSMUSG00000017167(Cntnap1)" "ENSG00000174469(CNTNAP2),ENSG00000155052(CNTNAP5),ENSG00000152910(CNTNAP4),ENSG00000106714(CNTNAP3),ENSG00000154529(CNTNAP3B),ENSG00000108797(CNTNAP1)" " embryonic stage | stage >=11 , embryonic stage -- adult stage " " chordotonal organ

, central nervous system | restricted

, glial cell

, embryonic/larval proventriculus

, embryonic/larval pharynx

, tracheal system

, peripheral nervous system | restricted

, embryonic/larval esophagus

, scolopidium

, epidermis

, embryonic/larval salivary gland

, embryonic/larval hindgut

" "viable,learning defective,neuroanatomy defective,lethal,recessive,decreased cell number,somatic clone,visible,paralytic,neurophysiology defective" "embryonic/larval salivary gland,germline cell,male,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,embryonic/larval brain,somatic clone,eye,wing,wing vein,leg,axolemma & nerve,epithelium,embryonic/first instar larval cuticle,dorsal,embryonic epidermis,neuromuscular junction,pleated septate junction,embryonic ganglionic branch & embryonic tracheole,dorsal trunk primordium,scolopidium,central nervous system,presumptive embryonic/larval tracheal system,abdominal lateral pentascolopidial chordotonal organ lch5,scolopidium & abdominal lateral pentascolopidial chordotonal organ lch5,septate junction & peripheral glial cell,septate junction" FBgn0034627 EfSec EfSec http://flybase.net/reports/FBgn0034627.html protein_coding_gene "0003924=GTPase activity, 0003746=translation elongation factor activity, 0005525=GTP binding" "0006451=translational readthrough, 0006414=translational elongation" "eEFsec, EFsec, EFSec, deEFsec, Efsec, SelB/eEFsec, Eftu, dEFsec, CG9841" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain" CG9841 16-Dec-15 2015_12 ENSDARG00000004696(eefsec) WBGene00008133(selb-1) ENSXETG00000002066(EEFSEC) ENSMUSG00000033216(Eefsec) ENSG00000132394(EEFSEC) "fertile,viable,short lived,chemical conditional" DRSC04571 I 1.546270683 0.216073631 0.930844801 -0.457775557 -1.479550061 -0.85808628 FBgn0004620 GluRIIA Glutamate receptor IIA http://flybase.net/reports/FBgn0004620.html protein_coding_gene "0004970=ionotropic glutamate receptor activity, 0008066=glutamate receptor activity, 0015277=kainate selective glutamate receptor activity, 0005234=extracellular-glutamate-gated ion channel activity" "0060074=synapse maturation, 0007268=synaptic transmission, 0035249=synaptic transmission, glutamatergic, 0030510=regulation of BMP signaling pathway, 0007274=neuromuscular synaptic transmission, 0046928=regulation of neurotransmitter secretion, 0006811=ion transport, 0060025=regulation of synaptic activity" "0097482=muscle cell postsynaptic density, 0008328=ionotropic glutamate receptor complex, 0045211=postsynaptic membrane, 0031594=neuromuscular junction, 0005886=plasma membrane" "DGluRIIA, DgluRII, DmelGluRIIA, glutamate receptor subunit IIA, DGluR-IIA, GluRII-A, gluRIIA, DGluR-II, GluR2a, Glu-RIIA, DGluRIIa, GluRII, dGluRII, GluR, glutamate IIA receptor, dglurIIA, GlurIIA, D-GluRIIA, dGluRIIA, glutamate receptor, GluR-IIA, unnamed, GluRIIa, dglur-IIA, Glu-RII, gluriia, glurIIA, DGluR2a, CG6992, glutamate receptor IIA, GluR[[IIa]], GluR2" "IPR001828=Receptor, ligand binding region, IPR001508=Ionotropic glutamate receptor, metazoa, IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR028082=Periplasmic binding protein-like I" CG6992 16-Dec-15 2015_12 embryonic stage | stage 17 larval neuromuscular junction

"wild-type,neurophysiology defective,viable,neuroanatomy defective,recessive,locomotor behavior defective,heat sensitive,lethal" "NMJ bouton,synapse, with Df(2L)SP22, Df(2L)cl-h4, ,synapse,synaptic vesicle,bouton,embryonic/larval neuromuscular junction,neuromuscular junction,t-bar,heat sensitive,type I bouton,synapse, with Df(2L)SP22, Df(2L)cl-h4, RapGAP1-OK6,presynaptic active zone membrane, with Df(2L)SP22, Df(2L)cl-h4, RapGAP1-OK6,postsynaptic membrane, with Df(2L)SP22, Df(2L)cl-h4, RapGAP1-OK6,synaptic vesiclehow-24B,neuromuscular junction | larval stagehow-24B,synapseMhc.PW,neuromuscular junction | larval stageMhc.PW" FBgn0038320 Sra-1 specifically Rac1-associated protein 1 http://flybase.net/reports/FBgn0038320.html protein_coding_gene 0017048=Rho GTPase binding "0030866=cortical actin cytoskeleton organization, 0006909=phagocytosis, 0001745=compound eye morphogenesis, 0008360=regulation of cell shape, 0030031=cell projection assembly, 0033627=cell adhesion mediated by integrin, 0007411=axon guidance, 0050807=regulation of synapse organization, 0000902=cell morphogenesis" "0045177=apical part of cell, 0045202=synapse, 0031209=SCAR complex, 0005737=cytoplasm" "Sra1/PIR121, sra1, CG4931, dSra, Specifically Rac1-associated protein 1, Sra1, cyfip, Sra, sra-1, DSra-1, PIR121, PIR121/Sra-1, Sra-1/CYFIP, CYFIP1/2, CYFIP, specifically, Rac-1 associated protein 1" "IPR009828=Protein of unknown function DUF1394, IPR008081=Cytoplasmic FMR1-interacting" CG4931 16-Dec-15 2015_12 "ENSDARG00000044345(cyfip1),ENSDARG00000036375(zgc:194528)" WBGene00001579(gex-2) ENSXETG00000001502(CYFIP2) "ENSMUSG00000020340(Cyfip2),ENSMUSG00000030447(Cyfip1)" "ENSG00000068793(CYFIP1),ENSG00000055163(CYFIP2)" "visible,viable,fertile,partially lethal - majority live,lethal - all die before end of P-stage,some die during pharate adult stage,cell shape defective,lethal,recessive,neuroanatomy defective,dominant,germline clone,somatic clone" "eye | adult stage,photoreceptor | adult stage,eye,cone cell,ommatidium,retina,lens,interommatidial bristle,rhabdomere | pharate adult stage,photoreceptor,rhabdomere | pupal stage,microchaeta,trichogen cell & actin filament & pupa.PC,adult head & macrochaeta.PC,intersegmental nerve,axon,neuromuscular junction & synapse,longitudinal connective,commissure,synapse,bouton,presumptive embryonic/larval central nervous system,germline clone,embryonic/larval neuromuscular junction,somatic clone,rhabdomere | adult stage | somatic clone,S2 cell-line & filopodium | ectopic,S2 cell-line & actin filament | ectopic,photoreceptor cell & growth cone & larval brainey.PH,photoreceptor cell | wandering third instar larval stage,larval neuromuscular junction & bouton" FBgn0002683 mat(3)1 maternal lethal 1 http://flybase.net/reports/FBgn0002683.html gene 0048477=oogenesis 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,non-rescuable maternal effect" "cycle 14 embryo,maternal effect,pole cell,non-rescuable maternal effect,blastoderm embryo,nucleus | blastoderm stage | non-rescuable maternal effect,syncytial blastoderm embryo" FBgn0014391 sun stunted http://flybase.net/reports/FBgn0014391.html "FBgn0014975, FBgn0040875, FBgn0047007, FBgn0047155" protein_coding_gene "0001664=G-protein coupled receptor binding, 0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism, 0046933=proton-transporting ATP synthase activity, rotational mechanism, 0046961=proton-transporting ATPase activity, rotational mechanism" "0015992=proton transport, 0015986=ATP synthesis coupled proton transport, 0006979=response to oxidative stress, 0046331=lateral inhibition, 0045745=positive regulation of G-protein coupled receptor protein signaling pathway, 0008340=determination of adult lifespan" "0000275=mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), 0005615=extracellular space" "Sun, ATP synthase epsilon chain, ATPsynepsilon, ATPE, ATP5E, BcDNA:RH48911, CG9032, ATP synthase Epsilon chain, ATP synthase, epsilon subunit, Stunted, F0/F1 ATP synthase Epsilon, l(1)XV, BcDNA:RE19513, l(1)13Fe" "IPR006721=ATPase, F1 complex, epsilon subunit, mitochondrial" CG9032 16-Dec-15 2015_12 YPL271W(ATP15) "WBGene00022582(ZC262.5),WBGene00017982(F32D1.2)" ENSMUSG00000016252(Atp5e) "ENSG00000124172(ATP5E),ENSG00000180389" "female sterile,lethal,partially,viable,recessive,wild-type,visible,long lived,stress response defective,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,dominant,chemical resistant,partially lethal - majority die,some die during pupal stage" "wing,nucleus | embryonic cycle 14 | germline clone | maternal effect,centrosome | germline clone | maternal effect,spindle | germline clone | maternal effect,nucleus | embryonic cycle 12 | germline clone | maternal effect,nucleus | embryonic cycle 13 | germline clone | maternal effect,nucleus | embryonic stage 5 | germline clone | maternal effect,egg,germline clone,maternal effect,chaeta,trichogen cell" FBgn0260341 GSd427 http://flybase.net/reports/FBgn0260341.html gene 16-Dec-15 2015_12 "lethal,neuroanatomy defective,viable" "ventral nerve cord,intersegmental nerve,eye photoreceptor cell" FBgn0000063 Mps1 Monopolar spindle 1 http://flybase.net/reports/FBgn0000063.html FBgn0038534 protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity" "0000705=achiasmate meiosis I, 0016321=female meiosis chromosome segregation, 0001666=response to hypoxia, 0007100=mitotic centrosome separation, 0032837=distributive segregation, 0007126=meiotic nuclear division, 0000278=mitotic cell cycle, 0007143=female meiotic division, 0007094=mitotic spindle assembly checkpoint, 0033316=meiotic spindle assembly checkpoint, 0043060=meiotic metaphase I plate congression, 0044779=meiotic spindle checkpoint, 0006468=protein phosphorylation, 0033046=negative regulation of sister chromatid segregation" "0000776=kinetochore, 0000942=condensed nuclear chromosome outer kinetochore, 0005813=centrosome, 0005819=spindle" "altered disjunction, CG7643, Msp1, ald, monopolar spindles 1, Mps1, mps1, dMps1, Ald/Mps1, TKK" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG7643 16-Dec-15 2015_12 YDL028C(MPS1) ENSG00000112742(TTK) "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,mitotic cell cycle defective,conditional,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,female,viable,fertile,germline clone,partially lethal - majority die" "eye,ommatidium,wing,mitotic cell cycle | germline clone,anaphase & condensed nuclear chromosome | germ-line clone,nucleus | germline clone,polar body nucleus,germline clone,kinetochore | embryonic stage 5mat.ë±Tub67C.THsimVP16,meiosis & nuclear chromosomeED5780),meiosis & nuclear chromosome,oocyte,spindle microtubule & oocyte,spindle pole & oocyte,chromosome & oocyte" FBgn0001515 l(1)10Fi lethal (1) 10Fi http://flybase.net/reports/FBgn0001515.html gene 16-Dec-15 2015_12 "lethal,polyphasic,recessive,cell lethal,germline clone" FBgn0001386 l(1)2Br lethal (1) 2Br http://flybase.net/reports/FBgn0001386.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005624 Psc Posterior sex combs http://flybase.net/reports/FBgn0005624.html "FBgn0002071, FBgn0003153, FBgn0003644" protein_coding_gene "0008270=zinc ion binding, 0001047=core promoter binding, 0003677=DNA binding" "0007411=axon guidance, 0006342=chromatin silencing, 0035186=syncytial blastoderm mitotic cell cycle, 0006338=chromatin remodeling" "0031519=PcG protein complex, 0005725=intercalary heterochromatin, 0005704=polytene chromosome band, 0035102=PRC1 complex, 0005634=nucleus" "Posterior Sex Combs, vr14, PSC, Psc1, posterior-sex-combs, l(2)Psc, l(2)vr14, Posterior sex comb, 49Ea, Su(z)2-C, CG3886, l(2)49Ea, D-Bmi, posterior sex comb, psc, dPSC, posterior sex combs" "IPR001841=Zinc finger, RING-type, IPR018957=Zinc finger, C3HC4 RING-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG3886 16-Dec-15 2015_12 WBGene00020496(spat-3) " larval stage | third instar , pupal stage | 24 hr , embryonic stage -- adult stage , oogenesis stage && adult stage | female " " larval central nervous system

, adult brain

, ovary

, imaginal disc

" " embryonic stage , larval stage | third instar , larval stage | first instar " " embryonic/larval salivary gland

, imaginal disc

, larval brain

, ventral nerve cord

, central nervous system

, pole cell

" "viable,eye color defective,dominant,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,non-suppressor of variegation,partially lethal - majority die,homeotic,mitotic cell cycle defective,suppressor of variegation,non-enhancer of variegation,somatic clone" "wing,posterior compartment,alula,pigment cell,head & macrochaeta,scutum & macrochaeta,scutellum & macrochaeta,costal vein & macrochaeta,leg & macrochaeta,abdomen & macrochaeta,dorsal triple row & macrochaeta,ventral triple row & macrochaeta,dorsal double row & macrochaeta,ventral double row & macrochaeta,embryonic epidermis,denticle belt,macrochaeta,embryonic head,embryonic thorax,embryonic abdomen,mesothoracic leg,metathoracic leg,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,anaphase | embryonic stage,telophase | embryonic stage,sex comb,supernumerary,somatic clone" FBgn0002518 l(3)Sp19 lethal (3) Sp19 http://flybase.net/reports/FBgn0002518.html gene 16-Dec-15 2015_12 lethal FBgn0028331 l(1)G0289 lethal (1) G0289 http://flybase.net/reports/FBgn0028331.html FBgn0030194 protein_coding_gene 0016020=membrane "Mgn1457, CG2221, lethal (1) G0289, Lethal (1) G0289" "IPR016201=Plexin-like fold, IPR031152=Plexin domain-containing protein, IPR002165=Plexin repeat" CG2221 16-Dec-15 2015_12 ENSDARG00000059950(zplxdc2) WBGene00007982(pxd-1) ENSXETG00000016596(PLXDC2) "ENSMUSG00000026748(Plxdc2),ENSMUSG00000017417(Plxdc1)" "ENSG00000120594(PLXDC2),ENSG00000161381(PLXDC1)" "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,body color defective,long lived,male limited" mesothoracic tergum FBgn0032728 Tango6 Transport and Golgi organization 6 http://flybase.net/reports/FBgn0032728.html protein_coding_gene "0009306=protein secretion, 0007030=Golgi organization, 0007095=mitotic G2 DNA damage checkpoint" "0005829=cytosol, 0005794=Golgi apparatus" "TANGO6, CG18398" "IPR019414=RNA polymerase II assembly factor Rtp1, C-terminal domain 2, IPR016024=Armadillo-type fold, IPR019451=RNA polymerase II assembly factor Rtp1, C-terminal" CG18398 16-Dec-15 2015_12 ENSDARG00000034001(si:ch211-218c6.2) ENSXETG00000016378(TMCO7) ENSMUSG00000041949(Tmco7) ENSG00000103047(TMCO7) "lethal,partially lethal - majority die,visible" "embryonic/larval brain,mesothoracic tergum" DRSC02671 I -1.076371589 2.166374572 -0.667438859 -0.096834721 -0.781265197 0.590880216 FBgn0004179 Csp Cysteine string protein http://flybase.net/reports/FBgn0004179.html "FBgn0010827, FBgn0066009" protein_coding_gene "0048854=brain morphogenesis, 0016079=synaptic vesicle exocytosis, 0007269=neurotransmitter secretion, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 1903035=negative regulation of response to wounding, 0016191=synaptic vesicle uncoating, 0016192=vesicle-mediated transport, 0006457=protein folding, 0006887=exocytosis" "0043195=terminal bouton, 0061176=type Ib terminal bouton, 0061177=type Is terminal bouton, 0005886=plasma membrane, 0008021=synaptic vesicle" "csp29, DNAJC5, Cys, D.M.CSP, CSP32, Cysteine String Protein, cysteine string protein, Cysteine string protein 3, csp, D-CSP, cystein string protein, l(3)03988, csp32, DCSP-1, DSP/DNAJC5, ab49, anon-WO02059370.50, CSP, cysteine-string protein, Dcsp, CG6395, MAB ab49" "IPR018253=DnaJ domain, conserved site, IPR001623=DnaJ domain" CG6395 16-Dec-15 2015_12 "ENSDARG00000042948(dnajc5aa),ENSDARG00000004836(LOC797907),ENSDARG00000058147(dnajc5b),ENSDARG00000041896(dnajc5g)" WBGene00001032(dnj-14) ENSXETG00000013034(Q6DK83_XENTR) "ENSMUSG00000000826(Dnajc5),ENSMUSG00000027606(Dnajc5b)" "ENSG00000101152(DNAJC5),ENSG00000147570(DNAJC5B)" adult stage " adult head

, adult brain

, retina

" " adult stage , larval stage " " photoreceptor cell

, neuropil

, lamina neuropil

, neuromuscular junction &&of adult thorax

, lobula plate neuropil

, medulla neuropil

, neuromuscular junction

, bouton

, neuron

" "lethal,partially lethal - majority die,recessive,paralytic,heat sensitive,neurophysiology defective,courtship behavior defective,male,viable,reduced,conditional,partially,uncoordinated,short lived,wild-type,optomotor response defective,visible,hypoactive,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "axon | larval stage,neuromuscular junction,embryonic/larval neuromuscular junction,germline cell,male,neuromuscular junction | larval stage,wing,eye,ommatidium,interommatidial bristle" FBgn0086067 snoRNA:Me28S-A771 http://flybase.net/reports/FBgn0086067.html snoRNA_gene "Me28S-Am771, CR34696, Me28S-A771" CR34696 16-Dec-15 2015_12 FBgn0002998 oml ommatidialess http://flybase.net/reports/FBgn0002998.html gene ommatidiless 16-Dec-15 2015_12 visible "ocellus,antenna,head,eye,ommatidium" FBgn0040318 HGTX HGTX http://flybase.net/reports/FBgn0040318.html "FBgn0036430, FBgn0036431, FBgn0062262" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0070491=repressing transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0030182=neuron differentiation, 0007399=nervous system development, 0007417=central nervous system development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0010629=negative regulation of gene expression, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Nk6 homeobox, CG13475, Nkx6, Nk6, CG4745, nkx6, dNkx6" "IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif, IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG13475 16-Dec-15 2015_12 "neuroanatomy defective,viable" "intersegmental nerve,RP2 motor neuron,ectopic,U neuron,EL neuron,EW neuron,motor neuron,intersegmental nerve branch ISNb of A1-7,fascicle,interneuron & axon & longitudinal connective,RP neuron & axon & embryo,intersegmental nerve | embryonic stage" FBgn0034012 Hr51 Hormone receptor 51 http://flybase.net/reports/FBgn0034012.html protein_coding_gene "0043565=sequence-specific DNA binding, 0020037=heme binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003707=steroid hormone receptor activity, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding" "0016319=mushroom body development, 0045475=locomotor rhythm, 0048842=positive regulation of axon extension involved in axon guidance, 0048526=imaginal disc-derived wing expansion, 0016322=neuron remodeling, 0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis, 0007411=axon guidance, 0031103=axon regeneration, 0043401=steroid hormone mediated signaling pathway" 0005634=nucleus "CG16801/NR2E3, unf, Nr2e3, fdx, Drosophila hormone receptor 51, UNF, PNR, DHR51, unfulfilled, HR51, failure to deploy or expand, CG16801, NR2E3" "IPR013088=Zinc finger, NHR/GATA-type, IPR001723=Nuclear hormone receptor, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000536=Nuclear hormone receptor, ligand-binding domain" CG16801 16-Dec-15 2015_12 ENSDARG00000045904(nr2e3) WBGene00001400(fax-1) ENSXETG00000005219(NR2E3) ENSMUSG00000032292(Nr2e3) ENSG00000031544(NR2E3) "lethal,neuroanatomy defective,somatic clone,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,visible,male sterile,female sterile,recessive" "gamma Kenyon cell,somatic clone,axonTab2-201Y,dendriteTab2-201Y,mushroom body | adult stage,mushroom body vertical lobe | third instar larval stage,mushroom body | pupal stage,mushroom body gamma-lobe,adult mushroom body,mushroom body gamma-lobe | adult stage,mushroom body alpha-lobe | pupal stage,mushroom body alpha'-lobe | pupal stage,mushroom body beta-lobe | pupal stage,mushroom body beta'-lobe | pupal stage,mushroom body,heat sensitive,lobe system of adult mushroom body,wing,alpha/beta Kenyon cell,ganglion mother cell" DRSC06627 I 2.097364643 -0.199922496 -0.003925285 -0.870965047 -1.209909147 -0.004140585 FBgn0002173 l(2)Su(H) lethal (2) Su(H) http://flybase.net/reports/FBgn0002173.html gene "lethal (2) from Suppressor of Hairless, l(2)su(H)" 16-Dec-15 2015_12 lethal FBgn0000588 esc extra sexcombs http://flybase.net/reports/FBgn0000588.html protein_coding_gene "0046974=histone methyltransferase activity (H3-K9 specific), 0031491=nucleosome binding, 0008047=enzyme activator activity, 0046976=histone methyltransferase activity (H3-K27 specific), 0042054=histone methyltransferase activity, 0005515=protein binding" "0007517=muscle organ development, 0070734=histone H3-K27 methylation, 0016571=histone methylation, 0006342=chromatin silencing, 0016458=gene silencing, 0048666=neuron development, 0048813=dendrite morphogenesis, 0031062=positive regulation of histone methylation" "0000790=nuclear chromatin, 0005634=nucleus, 0035097=histone methyltransferase complex, 0005700=polytene chromosome, 0035098=ESC/E(Z) complex" "extra sex combs, extra sex comb, CG14941, sc, ESC, L41867, Extra sex combs, dESC, extra sexcombs, Esc, Extra sexcombs, Extra Sex Combs" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat" CG14941 16-Dec-15 2015_12 ENSDARG00000040548(eed) WBGene00003224(mes-6) ENSXETG00000010440(eed) ENSMUSG00000030619 ENSG00000074266(EED) " embryonic stage | stage 13 , embryonic stage | stage 8-13 , embryonic stage | early , embryonic stage | 0-8hr " " embryonic brain | restricted

, germ band

,

ubiquitous " " adult stage , embryonic stage , embryonic stage | early " " testis | restricted

, embryonic brain

, neuroblast

" "wild-type,visible,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,non-enhancer of variegation,non-suppressor of variegation,maternal effect,cell autonomous,somatic clone,sterile,lethal,germline clone,rescuable maternal effect,neuroanatomy defective,homeotic,radiation resistant,dominant,viable" "sex comb,photoreceptor cell R1,somatic clone,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,midgut constriction,denticle belt,maternal effect,embryonic abdominal segment 8,ectopic,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,prothoracic segment,mesothoracic segment,metathoracic segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,abdominal segment 9,abdominal segment 10,abdominal segment 11,segment,cell autonomous,leg,metathoracic tibial transverse bristle row,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 9,embryonic antennal segment,embryonic maxillary segment,embryonic labial segment,embryonic segment,germline clone,rescuable maternal effect,dendrite & dorsal multidendritic neuron ddaC | somatic clone,dendrite & dorsal multidendritic neuron ddaC | third instar larval stage,embryonic/first instar larval cuticle" FBgn0034708 Vps35 Vacuolar protein sorting 35 http://flybase.net/reports/FBgn0034708.html protein_coding_gene "0017137=Rab GTPase binding, 0008565=protein transporter activity" "0042147=retrograde transport, endosome to Golgi, 0015031=protein transport, 0006897=endocytosis, 0016192=vesicle-mediated transport" "0005768=endosome, 0030906=retromer complex, inner shell, 0005770=late endosome" "DmVps35, DVps35, vps35, VPS35, dvps35, Vps35, Dvps35, CG5625" IPR005378=Vacuolar protein sorting-associated protein 35 CG5625 16-Dec-15 2015_12 ENSDARG00000008224(vps35) YJL154C(VPS35) WBGene00006933(vps-35) ENSXETG00000003889(VPS35) ENSMUSG00000031696(Vps35) ENSG00000069329(VPS35) "partially lethal - majority die,some die during pupal stage,lethal,recessive,melanotic mass phenotype,neuroanatomy defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,maternal effect,visible,somatic clone,neurophysiology defective" "melanotic mass,plasmatocyte,supernumerary,lamellocyte,NMJ bouton,embryonic/larval hemocyte,embryonic/larval dorsal trunk,wing margin,somatic clone,photoreceptor cell,endosome | progressive,lysosome | progressive,follicle cell" FBgn0000463 Dl Delta http://flybase.net/reports/FBgn0000463.html "FBgn0011411, FBgn0062130" protein_coding_gene "0005112=Notch binding, 0005102=receptor binding, 0005509=calcium ion binding" "0035155=negative regulation of terminal cell fate specification, open tracheal system, 0007423=sensory organ development, 0042676=compound eye cone cell fate commitment, 0001736=establishment of planar polarity, 0048477=oogenesis, 0042067=establishment of ommatidial planar polarity, 0007424=open tracheal system development, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0008284=positive regulation of cell proliferation, 0007419=ventral cord development, 0048749=compound eye development, 0045465=R8 cell differentiation, 0048800=antennal morphogenesis, 0008347=glial cell migration, 0030718=germ-line stem cell maintenance, 0007498=mesoderm development, 0007399=nervous system development, 0030713=ovarian follicle cell stalk formation, 0008407=chaeta morphogenesis, 0007417=central nervous system development, 0007460=R8 cell fate commitment, 0007219=Notch signaling pathway, 0036011=imaginal disc-derived leg segmentation, 0050768=negative regulation of neurogenesis, 0007314=oocyte anterior/posterior axis specification, 0016330=second mitotic wave involved in compound eye morphogenesis, 0007422=peripheral nervous system development, 0046667=compound eye retinal cell programmed cell death, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0035157=negative regulation of fusion cell fate specification, 0045468=regulation of R8 cell spacing in compound eye, 0048863=stem cell differentiation, 0007474=imaginal disc-derived wing vein specification, 0007155=cell adhesion, 0048190=wing disc dorsal/ventral pattern formation, 0008586=imaginal disc-derived wing vein morphogenesis, 0007298=border follicle cell migration, 0016318=ommatidial rotation, 0007476=imaginal disc-derived wing morphogenesis, 0007015=actin filament organization, 0007398=ectoderm development, 0046331=lateral inhibition, 0001708=cell fate specification, 0008356=asymmetric cell division, 0030707=ovarian follicle cell development, 0007480=imaginal disc-derived leg morphogenesis, 0045931=positive regulation of mitotic cell cycle, 0007464=R3/R4 cell fate commitment" "0005912=adherens junction, 0030139=endocytic vesicle, 0016021=integral component of membrane, 0005886=plasma membrane, 0005768=endosome, 0031410=cytoplasmic vesicle, 0009986=cell surface, 0035003=subapical complex" "D, Delta, 1440/11, anon-WO0118547.269, DL, EC3-5, 1304/03, 1485/04, Complementation group 1, delta, 1053/14, E(ls)2, CG3619, 1423/11, 0926/11, C1, l(3)05151, 1119/09, 0495/20, delta D1, Overflow, CT12133, l(3)j8C3, l(3)92Ab, dmDelta" "IPR011651=Notch ligand, N-terminal domain, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR001881=EGF-like calcium-binding domain, IPR001774=Delta/Serrate/lag-2 (DSL) protein" CG3619 16-Dec-15 2015_12 "ENSDARG00000020219(dld),ENSDARG00000010791(dla),ENSDARG00000002336(dlc),ENSDARG00000070425(dll4),ENSDARG00000004232(dlb)" "ENSXETG00000022525(DLL1),ENSXETG00000021584(DLL4),ENSXETG00000002875(DLL3)" "ENSMUSG00000014773(Dll1),ENSMUSG00000027314(Dll4)" "ENSG00000198719(DLL1),ENSG00000128917(DLL4)" " embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage >=12 , embryonic stage | stage 5-6 , embryonic stage | early , embryonic stage | stage 7 , larval stage | third instar , embryonic stage | stage 11,12 , embryonic stage | stage 4-13 , embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 9-11 , embryonic stage | stage 8-11 " " neuroblast

, embryonic peripheral nervous system

, embryonic central nervous system

, ventral neurogenic region

, embryonic stomatogastric nervous system

, organism | 20-40% egg length

, proctodeum

, embryonic/larval hindgut

, optic lobe

, organism | 40-70% egg length

, mesectoderm

, sense organ

, procephalic neurogenic region

,

pair rule , photoreceptor cell R4

, peripheral nervous system

, organism | 60-90% egg length

, stomodeal ganglion

, posterior embryonic/larval midgut

, photoreceptor cell R6

, anterior embryonic/larval midgut

, photoreceptor cell R3

, inclusive hindgut primordium

, eye disc

, ventral midline | precursor

, embryonic/larval tracheal system

, stomatogastric nervous system

, photoreceptor cell R7

, organism | 0-20% egg length

, photoreceptor cell R1

, trachea

, morphogenetic furrow

, ectoderm

" " larval stage , larval stage | third instar , embryonic stage , adult stage && oogenesis stage , pupal stage | early , adult stage && oogenesis stage | stage S11 , prepupal stage , larval stage | first instar , larval stage | second instar , larval stage && pupal stage " " sensory mother cell &&of dorsal mesothoracic disc

, eye disc

, morphogenetic furrow | anterior to

, posterior embryonic/larval midgut

, morphogenetic furrow | posterior to

, embryonic/larval dorsal trunk

, nurse cell

, wing vein L3 | presumptive

, photoreceptor cell R7

, peripodial epithelium

, germarium region 1

, larval outer optic anlage | precursor

, photoreceptor cell R5

, macrochaeta | precursor

, sensillum campaniformium &&of wing vein L2

, embryonic/larval pharynx

, mesectoderm

, anterior embryonic/larval midgut

, centripetally migrating follicle cell

, sensory mother cell &&of microchaeta

, wing vein | presumptive

, germarium region 2

, antenno-maxillary complex

, ommatidial precursor cluster

, larval central nervous system

, follicle cell

, photoreceptor cell R6

, larval labral segment sense organ | precursor

, anterior midgut proper primordium

, scutum | presumptive

, wing hair

, ventral neurogenic region

, photoreceptor cell R8

, procephalic neurogenic region

, macrochaeta

, neurogenic region

, larval inner optic anlage | precursor

, germarium region 3

, embryonic/larval hindgut

, oocyte

, photoreceptor cell R3

, ventral nerve cord

, precursor cell of the stomatogastric nervous system

, proneural cluster &&of microchaeta

, cone cell

, morphogenetic furrow

, dorsal mesothoracic disc | restricted

, embryonic/larval proventriculus

, photoreceptor cell

, antennal disc

, ventral midline

, embryonic/larval lateral trunk

, microchaeta

, glial cell

, amnioproctodeal invagination

, embryonic optic lobe primordium

, photoreceptor cell R1

, photoreceptor cell R4

, wing hair | presumptive

, photoreceptor cell R2

" "visible,dominant,lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,somatic clone,neurogenic phenotype,wild-type,body color defective,cell lethalcell lethal,heat sensitive,female sterile,non-rescuable maternal effect,polyphasic,planar polarity defective,mitotic cell cycle defective,size defective,reduced,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,hyperplasia,increased cell number,decreased cell number" "posterior scutellar bristle,adult midgut,wing vein,wing,,macrochaeta,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,tarsal segment,metatarsus,eye,embryonic/larval somatic muscle,dMP2 neuron,vMP2 neuron,RP2sib neuron,RP2 motor neuron,Usib neuron,U neuron,ommatidium,embryonic epidermis,embryo,interfollicle cell,rhabdomere,interommatidial bristle,cone cell,ocellus,leg,sex comb,tormogen cell,trichogen cell,proventriculus inner layer primordium,proventriculus intermediate layer primordium,proventriculus outer layer primordium,embryonic proventriculus,keyhole structure,microchaeta,stomatogastric nervous system primordium,scutum,ectoderm,photoreceptor cell,adult thoracic sensillum,embryonic cardioblast,basal cylinder,dorsal hair,filzkorper,embryonic hindgut,crossvein,aCC neuron,pCC neuron,posterior crossvein,five-cell ommatidial precursor cluster,eye-antennal disc,ommatidial precursor cluster,primary pigment cell,secondary pigment cell,tertiary pigment cell,basal stalk,follicle cell,nurse cell,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,hub cell,embryonic/larval corpus cardiacum,border follicle cell,lamina anlage,medulla anlage,larval outer optic anlage,S2 cell-line,anterior embryonic/larval midgut,hub cell | first instar larval stage,morphogenetic furrow,embryonic/larval dorsal vessel,dorsal triple row,medial triple row,ventral triple row,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,neuroblast,embryonic/larval central nervous system,embryonic/larval peripheral nervous system,segment,joint,segment border muscle,anterior scutellar bristle,female germline stem cell,trichome of the posterior wing margin,eye disc,egg chamber,oocyte nucleus,scutellar bristle,germline cyst,polar follicle cell,oocyte,dorsal acute muscle,pericardial cell,tendon cell,principal midgut epithelial cell,ventral nervous system,embryonic/first instar larval cuticle,neurosecretory neuron,embryonic/larval dorsal branch,pigment cell,intersegmental nerve,exit glial cell,ovary,lens,antenna,-C253,wing margin,adult heart,dorsal cluster neuron,medulla,hs.PB,germarium cap cell,embryonic/larval lymph gland,crystal cell,pretarsus,wing disc,head,pronotum,postnotum,genitalia,klu-G410,eye disc |,tracheal branch primordium,embryonic/larval dorsal trunk,btl.PS,sense organ,l(3)31-1-31-1,ventral thoracic disc,neur-P72,leg sensillum,mitotic cell cycle,cone cell | pupal stage,mat.ë±Tub67C.THsimVP16,wing blade,peripheral glial cell,-537.4,embryonic/larval neuron,chaeta,germline stem cell" DRSC16648 I 0.478163604 3.397238406 0.276366035 0.470581949 0.411791169 -0.172038097 FBgn0001168 h hairy http://flybase.net/reports/FBgn0001168.html "FBgn0011517, FBgn0019807, FBgn0019998" protein_coding_gene "0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0070888=E-box binding, 0046983=protein dimerization activity, 0003677=DNA binding, 0005515=protein binding, 0008134=transcription factor binding" "0035239=tube morphogenesis, 0007424=open tracheal system development, 0035289=posterior head segmentation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0031323=regulation of cellular metabolic process, 0007460=R8 cell fate commitment, 0007435=salivary gland morphogenesis, 0008407=chaeta morphogenesis, 0007366=periodic partitioning by pair rule gene, 0035290=trunk segmentation, 0001666=response to hypoxia, 0061024=membrane organization, 0000902=cell morphogenesis, 0007399=nervous system development, 0045892=negative regulation of transcription, DNA-templated, 0007431=salivary gland development" 0005634=nucleus "CG6494, l(3)08247, HRY, H, dDr1, bHLHc14, 8247, l(3)rM384, bHLHb39, Hairy, brr, hry, barrel" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG6494 16-Dec-15 2015_12 " embryonic stage | late , embryonic stage " adult salivary gland primordium

" embryonic stage | blastoderm , embryonic stage | cycle 14 , embryonic stage | stage 11-14 , embryonic stage | stage 14-16 , embryonic stage | stage 10 , embryonic stage | <=stage 9 , embryonic stage | stage 10, 11 , embryonic stage | stage 9-16 , embryonic stage | stage <=9 , embryonic stage | stage 5 " " organism | striped

,

pair rule , somatic mesoderm

, embryonic hindgut

, stomodeum

, organism | 80-100% egg length

, embryonic/larval tracheal pit

, proctodeum

, median tooth | precursor

, anal plate

, visceral mesoderm

, labral segment

" "pair rule phenotype,lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,somatic clone,wild-type,female,male,partially lethal - majority die,embryonic/larval segmentation phenotype,reduced,dominant" "embryonic/first instar larval cuticle,macrochaeta,embryo,wing,posterior compartment,stomatogastric nervous system,cuticle,segment,scutellum & macrochaeta,haltere & macrochaeta,head capsule & macrochaeta,ectopic,larval abdominal segment 4,adult abdominal segment 4,neuron,wing sensillum,wing vein L2 & macrochaeta & adult,microchaeta & mesothoracic tergum | supernumerary,microchaeta | ectopic & scutellum,medial triple row,wing margin bristle,wing hair,wing hair & wing vein L2,dorsal triple row,chemosensory ventral triple row bristle,wing & neuron & glial cell,glial cell,wing vein,wing vein & wing sensillum | ectopic | somatic clone,adult thorax & microchaeta | ectopic | somatic clone,mesothoracic tergum & macrochaeta | ectopic | conditional cs,wing cell,wing vein L2,eye,mouthpart,female,head,abdomen,embryonic/first instar larval cuticle & mesothoracic segment,presumptive embryonic salivary gland,larval midgut & embryo & epidermis,larval abdominal segment 2,larval abdominal segment 6,larval abdominal segment 8,denticle belt,embryonic labial segment,wing & macrochaeta & adult,somatic clone,wing & macrochaeta | somatic clone,tracheal system,rhabdomere,embryonic epidermis,extended germ band embryo,prothoracic segment,mesothoracic segment,metathoracic segment,abdominal segment 1,abdominal segment 2,larval metathoracic segment,larval abdominal segment 7,larval abdominal segment 3,larval head,larval abdominal segment 1,larval abdominal segment 5,larval mesothoracic segment,denticle,mesothoracic tarsal bristle,mesothoracic metatarsus,prothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,abdominal segment 4,abdominal 9 ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,pigment cell" FBgn0028683 spt4 spt4 http://flybase.net/reports/FBgn0028683.html FBgn0022179 protein_coding_gene "0003682=chromatin binding, 0046982=protein heterodimerization activity, 0008270=zinc ion binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0032785=negative regulation of DNA-templated transcription, elongation, 0016582=non-covalent chromatin modification, 0032786=positive regulation of DNA-templated transcription, elongation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006368=transcription elongation from RNA polymerase II promoter" "0008023=transcription elongation factor complex, 0005634=nucleus" "dDSIF, 142904_at, DSIF, dspt4, Dspt4, l(2)k05316, Spt4, CG12372, SPT4" "IPR009287=Transcription initiation Spt4, IPR022800=Spt4/RpoE2 zinc finger, IPR016046=Transcription initiation Spt4-like, IPR029040=RNA polymerase subunit RPABC4/transcription elongation factor Spt4" CG12372 16-Dec-15 2015_12 ENSDARG00000033143(zgc:92824) YGR063C(SPT4) WBGene00005014(spt-4) ENSXETG00000025331(SUPT4H1) ENSMUSG00000020485(Supt4h1) ENSG00000213246(SUPT4H1) "lethal,recessive,partially lethal - majority die" FBgn0028988 Spn42Dd Serpin 42Dd http://flybase.net/reports/FBgn0028988.html FBgn0033114 protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0032504=multicellular organism reproduction, 0010951=negative regulation of endopeptidase activity, 0045861=negative regulation of proteolysis, 0002784=regulation of antimicrobial peptide production, 0030162=regulation of proteolysis, 0050832=defense response to fungus" 0005615=extracellular space "Serine protease inhibitor 1, Spn42Dd, serpin 1, sp1, CG9456, Spn1" "IPR023796=Serpin domain, IPR000215=Serpin family" CG9456 16-Dec-15 2015_12 ENSDARG00000034168(serpini1) "WBGene00005643(srp-2),WBGene00005648(srp-7),WBGene00005647(srp-6),WBGene00005644(srp-3),WBGene00005642(srp-1)" "ENSXETG00000027588(serpinb6),ENSXETG00000027590(BC087996.1),ENSXETG00000025592()" "ENSG00000206073(SERPINB4),ENSG00000057149(SERPINB3),ENSG00000197641(SERPINB13),ENSG00000166634(SERPINB12),ENSG00000166396(SERPINB7),ENSG00000117601(SERPINC1)" "immune response defective,viable" FBgn0060359 l(3)S140207 lethal (3) S140207 http://flybase.net/reports/FBgn0060359.html gene 1402/07 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038126 CG8483 http://flybase.net/reports/FBgn0038126.html protein_coding_gene 0005576=extracellular region "IPR018244=Allergen V5/Tpx-1-related, conserved site, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR002413=Ves allergen, IPR014044=CAP domain" CG8483 16-Dec-15 2015_12 ENSDARG00000013293(crispld1b) WBGene00003055(lon-1) "ENSXETG00000011147(BC080935.1),ENSXETG00000011150(),ENSXETG00000011152(BC064231.1),ENSXETG00000011148(BC090555.1),ENSXETG00000010986(CRISP1)" ENSMUSG00000033633(Clec18a) "lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0013471 l(1)10P4 lethal (1) 10P4 http://flybase.net/reports/FBgn0013471.html gene 16-Dec-15 2015_12 "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0001179 hay haywire http://flybase.net/reports/FBgn0001179.html "FBgn0004376, FBgn0015830" protein_coding_gene "0003677=DNA binding, 0004386=helicase activity, 0004003=ATP-dependent DNA helicase activity, 0000990=core RNA polymerase binding transcription factor activity, 0043140=ATP-dependent 3'-5' DNA helicase activity, 0005524=ATP binding" "0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0001111=promoter clearance from RNA polymerase II promoter, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0006289=nucleotide-excision repair, 0009411=response to UV, 0001113=transcriptional open complex formation at RNA polymerase II promoter" "0005634=nucleus, 0005675=holo TFIIH complex" "i50, ms(3)nc2, TFIIH, DhR25, CG8019, hwr, Haywire, DmXPB, DhXPB, Xpb, Xpb/hay, XPB, ERCC3, nc2, Hay" "IPR006935=Helicase/UvrB, N-terminal, IPR001650=Helicase, C-terminal, IPR001161=Helicase Ercc3, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG8019 16-Dec-15 2015_12 ENSDARG00000002402(ercc3) YIL143C(SSL2) WBGene00013441(Y66D12A.15) ENSMUSG00000024382(Ercc3) ENSG00000163161(ERCC3) embryonic stage -- adult stage "radiation sensitive,wild-type,viable,male sterile,male fertile,meiotic cell cycle defective,male,recessive,lethal,visible,partially,heat sensitive,female sterile,female fertile,reduced,partially lethal - majority die,increased cell death" "chaeta,wing,macrochaeta,microchaeta,adult abdomen & endocuticle,wing margin,meiotic cell cycle | male,embryonic/larval central nervous system,imaginal disc,adult abdomen & endocuticlelxd6)" DRSC11354 IK 3.361916789 0.454441399 -0.628132933 0.467182685 0.757526396 1.869605519 FBgn0040297 Nhe2 Na+/H+ hydrogen exchanger 2 http://flybase.net/reports/FBgn0040297.html "FBgn0032917, FBgn0032918" protein_coding_gene 0015385=sodium:proton antiporter activity "0055085=transmembrane transport, 0006814=sodium ion transport, 0006885=regulation of pH, 0006873=cellular ion homeostasis, 0030641=regulation of cellular pH, 0001745=compound eye morphogenesis" 0016021=integral component of membrane "Nhe2, CG9256, DmNHE2, CG9255, NHE2, Dnhe2, nhe2" "IPR006153=Cation/H+ exchanger, IPR004709=Na+/H+ exchanger, IPR018422=Cation/H+ exchanger, CPA1 family" CG9256 16-Dec-15 2015_12 WBGene00003943(pbo-4) ENSXETG00000008087(SLC9A5) "ENSMUSG00000036123(Slc9a3),ENSMUSG00000014786(Slc9a5)" "ENSG00000066230(SLC9A3),ENSG00000135740(SLC9A5)" "viable,fertile,cell lethalcell lethal,recessive,somatic clone,lethal - all die before end of larval stage,some die during larval stage,planar polarity defective" "embryonic/larval digestive system,embryonic/larval fat body,ommatidium,eye,eye photoreceptor cell" DRSC03172 E 1.124920811 -0.018991303 1.789548173 -0.296814038 0.764371682 -0.201884982 FBgn0060836 l(3)S049701 lethal (3) S049701 http://flybase.net/reports/FBgn0060836.html gene "l(3)S049706a, l(3)S049706, 0497/06" 16-Dec-15 2015_12 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0000347 condensed condensed http://flybase.net/reports/FBgn0000347.html gene con 16-Dec-15 2015_12 "visible,recessive,partially lethal - majority die,sterile,male" "thorax,abdomen,eye,wing,macrochaeta,posterior scutellar bristle,posterior vertical bristle" FBgn0034354 GstE11 Glutathione S transferase E11 http://flybase.net/reports/FBgn0034354.html protein_coding_gene 0004364=glutathione transferase activity "0006749=glutathione metabolic process, 0022008=neurogenesis" 0005737=cytoplasm "GSTE11, cg5224, gste11, CG5224" "IPR012336=Thioredoxin-like fold, IPR004045=Glutathione S-transferase, N-terminal, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG5224 16-Dec-15 2015_12 YLL060C(GTT2) "lethal,neuroanatomy defective,viable,visible,fertile" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0005190 l(2)S50 lethal of Seto 50 http://flybase.net/reports/FBgn0005190.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "eye,genitalia,epidermis" FBgn0021906 RFeSP Rieske iron-sulfur protein http://flybase.net/reports/FBgn0021906.html "FBgn0025542, FBgn0031352" protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding, 0008121=ubiquinol-cytochrome-c reductase activity" "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" "0005739=mitochondrion, 0005750=mitochondrial respiratory chain complex III, 0005875=microtubule associated complex" "RIESKE IRON-SULFUR PROTEIN, Rieske iron sulphur protein, l(2)k11704, Ubiquinol-cytochrome c oxidoreductase Iron-sulfur, CG7361, UQCR-RFeSP, Ubiquinol-cytochrome c reductase Iron-sulfur subunit, RISP, Rieske iron- sulfur protein of complex III, Noble, UCRI, Ubiquinol-cytochrome C reductase iron-sulfur subunit, Not out of the blue, anon-EST:Posey219, RfeSP, Rieske iron sulfur protein, Ubiquinol-cytochrome c reductase Rieske iron sulfur protein, H, Rieske Iron-Sulfur Protein" "IPR017941=Rieske [2Fe-2S] iron-sulphur domain, IPR014349=Rieske iron-sulphur protein, IPR006317=Ubiquinol-cytochrome c reductase, iron-sulphur subunit, IPR004192=Ubiquinol cytochrome reductase, transmembrane domain, IPR005805=Rieske iron-sulphur protein, C-terminal" CG7361 16-Dec-15 2015_12 ENSDARG00000007745(uqcrfs1) YEL024W(RIP1) WBGene00002162(isp-1) "lethal,recessive" lysosome & larval fat body | somatic clone | cell autonomous DRSC00702 IE -0.584617391 -1.511153549 -2.110558686 -0.581680779 0.025972042 0.911318913 FBgn0028003 l(3)S119307b lethal (3) S119307b http://flybase.net/reports/FBgn0028003.html gene "l(3)S119307, 1337/05" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0043854 slam slow as molasses http://flybase.net/reports/FBgn0043854.html "FBgn0024181, FBgn0031806" protein_coding_gene "0008354=germ cell migration, 0007349=cellularization, 0061024=membrane organization, 0008104=protein localization, 0036089=cleavage furrow formation, 0036090=cleavage furrow ingression" 0032154=cleavage furrow "Slam, wdo, CG9506, waldo" CG9506 16-Dec-15 2015_12 embryonic stage | embryonic cycle 13-14 embryonic stage | cycle 14 furrow canal

viable "germline cell,embryonic/larval midgut primordium,gonadal sheath proper primordium,cycle 14 embryo,furrow canal,germline clone" DRSC03240 I 1.596482818 -0.027722038 -0.103578729 1.21276141 -0.001593993 -0.50012749 FBgn0010395 Itgbn Integrin betanu subunit http://flybase.net/reports/FBgn0010395.html "FBgn0010216, FBgn0025116" protein_coding_gene "0046982=protein heterodimerization activity, 0004872=receptor activity, 0050839=cell adhesion molecule binding" "0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0033627=cell adhesion mediated by integrin, 0007476=imaginal disc-derived wing morphogenesis, 0035011=melanotic encapsulation of foreign target, 0007155=cell adhesion, 0042048=olfactory behavior, 0046716=muscle cell cellular homeostasis, 0043277=apoptotic cell clearance, 0007160=cell-matrix adhesion, 0016337=single organismal cell-cell adhesion, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0006909=phagocytosis" "0008305=integrin complex, 0016021=integral component of membrane" "betagr;-nu, integrin betanu subunit, beta[nu] integrin, CG1762, Integrin bn, betav, betanu integrin, beta[[v]], betaInt[nu], betav integrin, beta[v]integrin, betanu Integrin, integrinbetanu, Beta[[nu]], integrin beta v, integrin beta neu, betaInt, Itgbetanu, betanu, beta-nu, betaInt-nu, Integrin betanu subunit, betaInt nu, CT5192, beta[nu]-integrin, betaV-integrin, Fly betanu" "IPR013111=EGF-like domain, extracellular, IPR013032=EGF-like, conserved site, IPR002369=Integrin beta subunit, N-terminal, IPR000742=EGF-like domain, IPR016201=Plexin-like fold, IPR015812=Integrin beta subunit, IPR002035=von Willebrand factor, type A, IPR014836=Integrin beta subunit, cytoplasmic domain" CG1762 16-Dec-15 2015_12 " embryonic stage , embryonic stage -- adult stage " endoderm &&of midgut

" larval stage , embryonic stage " " embryonic/larval proventriculus

, endoderm &&of midgut

, hindgut imaginal ring

, midgut imaginal island

, gastric caecum

" "viable,smell perception defective,immune response defective,sleep defective,fertile,neuroanatomy defective,visible" "NMJ bouton,supernumerary,neuromuscular junction | third instar larval stage,intersegmental nerve,anterior fascicle & synapse,neuromuscular junction | third instar larval stageelav.PU,trichogen cell,embryonic hemocyte,embryonic/larval hemocyte | third instar larval stage" FBgn0035798 frac faulty attraction http://flybase.net/reports/FBgn0035798.html protein_coding_gene 0005509=calcium ion binding 0007412=axon target recognition "CG7526, CT16044" "IPR000436=Sushi/SCR/CCP domain, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR001881=EGF-like calcium-binding domain, IPR018097=EGF-like calcium-binding, conserved site, IPR003410=HYR domain, IPR000742=EGF-like domain, IPR026823=Complement Clr-like EGF domain, IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site" CG7526 16-Dec-15 2015_12 "ENSG00000049323(LTBP1),ENSG00000119681(LTBP2),ENSG00000168056(LTBP3),ENSG00000090006(LTBP4),ENSG00000166147(FBN1),ENSG00000138829(FBN2),ENSG00000142449(FBN3)" "viable,fertile,neuroanatomy defective" "intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,intersegmental nerve branch ISNb of A1-7 | embryonic stage" FBgn0028233 l(3)S003606 lethal (3) S003606 http://flybase.net/reports/FBgn0028233.html gene "l(3)s003606, 0036/06" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0001526 l(1)11Eb lethal (1) 11Eb http://flybase.net/reports/FBgn0001526.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033755 ClC-b Chloride channel-b http://flybase.net/reports/FBgn0033755.html protein_coding_gene "0005247=voltage-gated chloride channel activity, 0005254=chloride channel activity" "0006821=chloride transport, 0050975=sensory perception of touch, 0055085=transmembrane transport" 0016020=membrane "DmClCb, CG8594, DmClC-b, Clcn7" "IPR014743=Chloride channel, core, IPR001807=Chloride channel, voltage gated, IPR000644=CBS domain" CG8594 16-Dec-15 2015_12 ENSDARG00000019556(clcn7) WBGene00000533(clh-6) ENSXETG00000009124(CLCN7) ENSMUSG00000036636(Clcn7) ENSG00000103249(CLCN7) "viable,touch sensitivity defective,lethal" DRSC07220 K 0.53449946 0.000177269 0.918218065 -0.233290482 0.716640119 2.627080407 FBgn0039932 fuss fussel http://flybase.net/reports/FBgn0039932.html protein_coding_gene "0046332=SMAD binding, 0070410=co-SMAD binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0007474=imaginal disc-derived wing vein specification, 0030514=negative regulation of BMP signaling pathway" "0005737=cytoplasm, 0005634=nucleus" "CORL, CG11093" "IPR014890=c-SKI SMAD4-binding domain, IPR009061=Putative DNA-binding domain, IPR023216=Transcription regulator SKI/SnoN, IPR003380=Transforming protein Ski, IPR010919=SAND domain-like" CG11093 16-Dec-15 2015_12 ENSXETG00000007811(LBXCOR1) ENSG00000215474 "viable,lethal,male limited,partially lethal - majority die,female limited,size defective,developmental rate defective,short lived,female semi-fertile" "wing,wing vein,wing vein L2,wing vein L5,posterior crossvein,sensillum campaniformium of dorsal radius,alpha/beta Kenyon cell,gamma Kenyon cell,adult mushroom body,vertical lobe of adult mushroom body" DRSC21452 I -0.818645365 -1.938636718 0.121231071 0.390358204 -0.920554847 0.406624597 FBgn0061121 l(3)S005005 lethal (3) S005005 http://flybase.net/reports/FBgn0061121.html gene 0050/05 16-Dec-15 2015_12 "lethal,recessive" FBgn0003132 Pp1-13C Protein phosphatase 1 at 13C http://flybase.net/reports/FBgn0003132.html FBgn0030632 protein_coding_gene 0004722=protein serine/threonine phosphatase activity "0022008=neurogenesis, 0006470=protein dephosphorylation, 0046692=sperm competition" 0000164=protein phosphatase type 1 complex "CG9156, PP1 beta13c, Protein phosphatase 1 13C, pp1-13C, PP1-13C, PP1, unnamed, PP1alpha-13C, PP1alpha13C, PP1c, PP13C, protein phosphatase 1, 13C, DmPp1-13C, Pp1, PP1 13C" "IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG9156 16-Dec-15 2015_12 YER133W(GLC7) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC20269 IE 2.46639853 -1.745927738 4.362067769 -2.283781921 -0.879603221 0.159815629 FBgn0002715 mei-S332 meiotic from via Salaria 332 http://flybase.net/reports/FBgn0002715.html FBgn0046271 protein_coding_gene "0007143=female meiotic division, 0007140=male meiosis, 0045132=meiotic chromosome segregation, 0007065=male meiosis sister chromatid cohesion, 0007062=sister chromatid cohesion" "0000780=condensed nuclear chromosome, centromeric region, 0005694=chromosome, 0005721=pericentric heterochromatin, 0000775=chromosome, centromeric region" "meiS332, MeiS332, BEST:LD13774, mei-s332, mei-S322, CG5303, MEI-S332, MEI-S322, Shugoshin, meiotic from Salaria 332, Mei-S332, meiS322, Mei-S332/Shugoshin" "IPR011515=Shugoshin, C-terminal, IPR011516=Shugoshin, N-terminal coiled-coil domain" CG5303 16-Dec-15 2015_12 " larval stage--adult stage , oogenesis stage && adult stage | female , spermatogenesis && adult stage , embryonic stage -- adult stage " " ovary

, testis

" "long lived,female limited,starvation stress response defective,temperature response defective,wild-type,meiotic cell cycle defective,recessive,mitotic cell cycle defective,male sterile,viable,semidominant,lethal,increased cell death" "meiosis II | female,neuroblast & mitotic cell cycleX58-6),meiosis II | male,mitosis,imaginal disc,wing disc,neuroblast & mitotic cell cycle69B" FBgn0033673 CG8298 http://flybase.net/reports/FBgn0033673.html protein_coding_gene 0004370=glycerol kinase activity 0005975=carbohydrate metabolic process "IPR018484=Carbohydrate kinase, FGGY, N-terminal, IPR018483=Carbohydrate kinase, FGGY, conserved site, IPR018485=Carbohydrate kinase, FGGY, C-terminal" CG8298 16-Dec-15 2015_12 viable FBgn0013674 mt:CoI mitochondrial Cytochrome c oxidase subunit I http://flybase.net/reports/FBgn0013674.html "FBgn0002867, FBgn0025247" protein_coding_gene "0020037=heme binding, 0005506=iron ion binding, 0004129=cytochrome-c oxidase activity" "1901214=regulation of neuron death, 0006123=mitochondrial electron transport, cytochrome c to oxygen, 0030431=sleep, 0006264=mitochondrial DNA replication, 0009060=aerobic respiration" "0005743=mitochondrial inner membrane, 0005739=mitochondrion, 0016021=integral component of membrane, 0005751=mitochondrial respiratory chain complex IV" "COX1, COXI, CO, Co I, COI, CO1, cytochrome c oxidase subunit I, anon-EST:fe1F8, cytochrome c oxidase, COX subunit I, mitochondrial cytochrome c oxidase subunit I, Cyt.ox.I, cytochrome oxidase, cytochrome c, mitochondrial cytochrome oxidase C (subunit I), CcO subunit I, cox1, COX subunit 1, Cyclooxygenase-1, CO I, CG34067, COX, coI, CoI, cytochrome oxidase subunit I, Cytochrome oxidase subunit I, COX I, mt-CO1, coxI, Cytochrome c oxidase, cytochrome oxidase I, I, Cytochrome c oxidase subunit I, anon-fast-evolving-1F8" "IPR000883=Cytochrome c oxidase subunit I, IPR023616=Cytochrome c oxidase, subunit I domain, IPR023615=Cytochrome c oxidase, subunit I, copper-binding site" CG34067 16-Dec-15 2015_12 ENSDARG00000063905 Q0045(COX1) WBGene00010964(MTCE.26) ENSMUSG00000064351 ENSG00000198804 "lethal - all die during P-stage,heat sensitive,viable,short lived,male sterile,neuroanatomy defective,female semi-sterile,locomotor behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,sterile" "germarium region 2b,heat sensitive,mechanosensory chaeta,rhabdomere,ommatidium,photoreceptor cell,flight muscle,eye" FBgn0259601 B0079 http://flybase.net/reports/FBgn0259601.html gene 16-Dec-15 2015_12 visible "anterior crossvein,wing vein L3,wing,antennal segment,arista" FBgn0028852 CG15262 http://flybase.net/reports/FBgn0028852.html protein_coding_gene "0006355=regulation of transcription, DNA-templated" 0005634=nucleus BG:DS07851.5 IPR007282=NOT2/NOT3/NOT5 CG15262 16-Dec-15 2015_12 viable FBgn0043900 pygo pygopus http://flybase.net/reports/FBgn0043900.html "FBgn0028951, FBgn0039853, FBgn0064198" protein_coding_gene "0001105=RNA polymerase II transcription coactivator activity, 0008270=zinc ion binding, 0005515=protein binding" "0007472=wing disc morphogenesis, 0006351=transcription, DNA-templated, 0009880=embryonic pattern specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048526=imaginal disc-derived wing expansion, 0035214=eye-antennal disc development, 0007223=Wnt signaling pathway, calcium modulating pathway, 0060232=delamination, 0022008=neurogenesis, 0030177=positive regulation of Wnt signaling pathway, 0016055=Wnt signaling pathway, 0048813=dendrite morphogenesis" 0005634=nucleus "gam, gammy legs, unnamed, BEST:LD21971, pygopous, pyg, Pygopus, CG11518, dPygo, Pygo, Dm Pygo, anon-WO02077023.1, pypo, pNB5.2" "IPR001965=Zinc finger, PHD-type, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG11518 16-Dec-15 2015_12 ENSDARG00000036772(pygo2) "ENSG00000171016(PYGO1),ENSG00000163348(PYGO2)" " larval stage , embryonic stage " organism

"visible,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal,recessive,germline clone,maternal effect,decreased cell death,somatic clone,segment polarity phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,pair rule phenotype,increased cell death,cell growth defective,cell shape defective,neuroanatomy defective,partially lethal - majority die" "eye,dorsocentral bristle,scutellar bristle,adult cuticle,leg,sex comb,wing,denticle belt,cuticle,embryonic epidermis,somatic clone,wing margin,imaginal disc,eye photoreceptor cell,ectopic,ommatidium,photoreceptor cell,RP2 motor neuron,embryonic/first instar larval cuticle,rescuable maternal effect,embryo,maternal effect,wing margin bristle,cell non-autonomous,germline clone,distal,midgut constriction 2,denticle,wing disc,cone cell,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0002469 l(3)SG24 lethal (3) SG24 http://flybase.net/reports/FBgn0002469.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye-antennal disc,wing disc,metathoracic leg disc" FBgn0035918 Cdc6 Cdc6 http://flybase.net/reports/FBgn0035918.html protein_coding_gene 0003689=DNA clamp loader activity "0006270=DNA replication initiation, 0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0051301=cell division" "0005656=nuclear pre-replicative complex, 0005634=nucleus" "CDC6, DmCdc6, cdc6, CG5971" "IPR015163=Cdc6, C-terminal domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR016314=Cell division protein Cdc6/18, IPR003593=AAA+ ATPase domain" CG5971 16-Dec-15 2015_12 ENSDARG00000009942(zgc:174506) YJL194W(CDC6) WBGene00000382(cdc-6) ENSXETG00000024394(cdc6) ENSMUSG00000017499(Cdc6) ENSG00000094804(CDC6) FBgn0030359 CG18130 http://flybase.net/reports/FBgn0030359.html protein_coding_gene 0045454=cell redox homeostasis "IPR017937=Thioredoxin, conserved site, IPR012336=Thioredoxin-like fold" CG18130 16-Dec-15 2015_12 ENSXETG00000001083(TXNDC6) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034259 P32 http://flybase.net/reports/FBgn0034259.html protein_coding_gene 0042393=histone binding "0050848=regulation of calcium-mediated signaling, 0006334=nucleosome assembly, 0007274=neuromuscular synaptic transmission, 0006338=chromatin remodeling, 0035042=fertilization, exchange of chromosomal proteins, 0035041=sperm chromatin decondensation" "0005739=mitochondrion, 0005634=nucleus, 0005759=mitochondrial matrix" "TAP, dp32, CG 6459, CG6459, p32" IPR003428=Mitochondrial glycoprotein CG6459 16-Dec-15 2015_12 ENSDARG00000039887(wu:fa14h03) WBGene00010303(cri-3) ENSXETG00000021363(C1QBP) ENSMUSG00000018446(C1qbp) ENSG00000108561(C1QBP) "paralytic,recessive,heat sensitive,neurophysiology defective,viable,fertile" FBgn0020270 mre11 meiotic recombination 11 http://flybase.net/reports/FBgn0020270.html protein_coding_gene "0004527=exonuclease activity, 0004519=endonuclease activity, 0030145=manganese ion binding" "0007095=mitotic G2 DNA damage checkpoint, 0000723=telomere maintenance, 0006289=nucleotide-excision repair, 0006974=cellular response to DNA damage stimulus, 0051276=chromosome organization, 0016233=telomere capping, 0006302=double-strand break repair" 0005634=nucleus "CG16928, Mre11, MRE11, 16928" "IPR007281=Mre11, DNA-binding, IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR003701=DNA repair protein Mre11" CG16928 16-Dec-15 2015_12 ENSDARG00000006394(mre11a) YMR224C(MRE11) WBGene00003405(mre-11) ENSXETG00000006417(MRE11A) ENSMUSG00000031928(Mre11a) ENSG00000020922(MRE11A) "lethal - all die before end of pupal stage,some die during pupal stage,female sterile,male fertile,mitotic cell cycle defective,lethal,maternal effect,radiation sensitive,recessive,viable" "chromosome & neuroblast | third instar larval stage 2,mitosis & nuclear chromosome,chromosome, telomeric region" FBgn0027083 Aats-met-m mitochondrial methionyl-tRNA synthetase http://flybase.net/reports/FBgn0027083.html "FBgn0038215, FBgn0038216, FBgn0051322" protein_coding_gene "0004825=methionine-tRNA ligase activity, 0005524=ATP binding" 0006431=methionyl-tRNA aminoacylation 0005759=mitochondrial matrix "CG8684, Aats-met, MetRS, CG31322, MRS, Methionyl-tRNA synthetase, CG9612" "IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR015413=Methionyl/Leucyl tRNA synthetase, IPR014758=Methionyl-tRNA synthetase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG31322 16-Dec-15 2015_12 ENSDARG00000009218(LOC566565) YGR171C(MSM1) WBGene00013678(Y105E8A.20) ENSXETG00000018187(MARS2) ENSMUSG00000046994(Mars2) ENSG00000152428 embryonic stage

ubiquitous "neurophysiology defective,somatic clone,conditional,neuroanatomy defective,short lived,flightless,partially lethal - majority die,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,lethal,lethal - all die before end of larval stage,some die during third instar larval stage,decreased cell size,cell autonomous" "mitochondrion,eye photoreceptor cell,conditional,retinal pigment cell,indirect flight muscle,imaginal disc,embryonic/larval brain,wing disc,somatic clone,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0004406 tam tamas http://flybase.net/reports/FBgn0004406.html "FBgn0000476, FBgn0001960, FBgn0020604" protein_coding_gene "0003677=DNA binding, 0003887=DNA-directed DNA polymerase activity, 0008296=3'-5'-exodeoxyribonuclease activity" "0006261=DNA-dependent DNA replication, 0007562=eclosion, 0008340=determination of adult lifespan, 0006264=mitochondrial DNA replication" "0005739=mitochondrion, 0005760=gamma DNA polymerase complex" "DNApol-gamma125, AAC47658, MtPolA, polgamma-alpha, DNA polymerase gamma, BG:DS00941.6, Tam, lethal 5 in the black-reduced region, mtPolA, lethal(2)34Dc, DNA polymerase gamma 125kD, DNApol-gamma, Polgamma, D-pol gamma-alpha, unnamed, catalytic(alpha)subunit, mtDNA polymerase alpha, cDNA 2, catalytic subunit of the mitochondrial DNA polymerase, mtDNA pol, Tamas, l(2)brS, CG8987, pol gamma, polgamma, alpha subunit, l(2)34Dc, lethal 14 in the black-reduced region, 34Dc, anon-34Dc, l(2)br5, POLGalpha, mitochondrial gamma polymerase, l(2)br14, br5, pol gamma-alpha" "IPR012337=Ribonuclease H-like domain, IPR002297=DNA-directed DNA-polymerase, family A, mitochondria, IPR019760=DNA-directed DNA polymerase, family A, conserved site, IPR001098=DNA-directed DNA polymerase, family A, palm domain" CG8987 16-Dec-15 2015_12 "ENSDARG00000060951(LOC560613),ENSDARG00000070364(LOC100150924)" YOR330C(MIP1) WBGene00013258(polg-1) ENSXETG00000017750(POLG) ENSMUSG00000039176(Polg) ENSG00000140521(POLG) "lethal,recessive,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,visible,viable,poor,neuroanatomy defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,short lived" "eye disc,photoreceptor cell,photoreceptor cell & axon,head bristle,scutum & macrochaeta,wing,wing vein,eye,adult thorax & macrochaeta,mitochondrion,adult cuticle,leg,macrochaeta,pupal cuticle,mesothoracic tergum,wing margin bristle,dopaminergic PPL1 neuron,dopaminergic PPL2ab neuron,dopaminergic PPL2c neuron,dopaminergic PPM1 neuron,dopaminergic PPM2 neuron,dopaminergic PPM3 neuron,dopaminergic PAL neuron,serotonergic neuron" FBgn0030323 CG2371 http://flybase.net/reports/FBgn0030323.html "FBgn0030324, FBgn0030325" protein_coding_gene "CG2442, CG2443" "IPR017920=COMM domain, IPR009886=HCaRG" CG2371 16-Dec-15 2015_12 ENSXETG00000018731(TGas127d11.1) ENSMUSG00000042705(Commd10) ENSG00000145781(COMMD10) "viable,fertile,visible" trichogen cell FBgn0016934 smi61A smell impaired 61A http://flybase.net/reports/FBgn0016934.html gene 0042048=olfactory behavior 16-Dec-15 2015_12 "smell perception defective,behavior defective,recessive" FBgn0003387 shb shortened bristles http://flybase.net/reports/FBgn0003387.html gene 16-Dec-15 2015_12 "female sterile,male fertile,viable,male,reduced,visible" "wing,macrochaeta" FBgn0002770 mk murky http://flybase.net/reports/FBgn0002770.html gene 0048477=oogenesis fs(1)M7 16-Dec-15 2015_12 "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage,viable,male,reduced,male fertile,visible,eye color defective,body color defective" "egg,pigment cell,adult thorax,trident" FBgn0037906 PGRP-LB Peptidoglycan recognition protein LB http://flybase.net/reports/FBgn0037906.html protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding, 0004040=amidase activity, 0008745=N-acetylmuramoyl-L-alanine amidase activity, 0042834=peptidoglycan binding" "0061060=negative regulation of peptidoglycan recognition protein signaling pathway, 0016045=detection of bacterium, 0000270=peptidoglycan metabolic process, 0006955=immune response, 0006952=defense response, 0009253=peptidoglycan catabolic process, 0050830=defense response to Gram-positive bacterium" "0005887=integral component of plasma membrane, 0005576=extracellular region" "Peptidoglycan-recognition protein-LB precursor, pgrp-LB, CG14704" "IPR017331=Peptidoglycan recognition protein, PGRP-S, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510=Peptidoglycan recognition protein, IPR002502=N-acetylmuramoyl-L-alanine amidase domain" CG14704 16-Dec-15 2015_12 "immune response defective,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,fertile,short lived" FBgn0013548 l(2)dtl lethal-(2)-denticleless http://flybase.net/reports/FBgn0013548.html FBgn0034895 protein_coding_gene "0022008=neurogenesis, 0051726=regulation of cell cycle" "0005737=cytoplasm, 0005634=nucleus" "DTL83, cdt2, Cdt2, CG11295, L2DTL" "IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG11295 16-Dec-15 2015_12 ENSDARG00000013472(zgc:63491) ENSXETG00000001979(AMBRA1) ENSMUSG00000037474(Dtl) ENSG00000150627(WDR17) " embryonic stage , embryonic stage -- adult stage "

ubiquitous "male sterile,female fertile,lethal - all die during larval stage,male fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective" "denticle belt,embryonic/larval neuroblast,ganglion mother cell" DRSC04697 IK -3.132139065 -2.204922322 -1.341869696 -0.977035388 5.454702345 5.976318844 FBgn0000419 db dark body http://flybase.net/reports/FBgn0000419.html gene 16-Dec-15 2015_12 "male fertile,viable,female,female semi-sterile,body color defective,lethal - all die before end of pupal stage,male,recessive,some die during pupal stage,lethal,visible" "adult cuticle,wing,cuticle" FBgn0003899 twg twisted genitals http://flybase.net/reports/FBgn0003899.html gene 16-Dec-15 2015_12 "visible,viable,male,reduced,male fertile" "eye,wing,wing vein,macrochaeta,genitalia,tergite" FBgn0004087 Dhfr Dihydrofolate reductase http://flybase.net/reports/FBgn0004087.html protein_coding_gene "0050661=NADP binding, 0004146=dihydrofolate reductase activity, 0005515=protein binding" "0015955=pyrimidine deoxyribonucleotide interconversion, 0009165=nucleotide biosynthetic process, 0006189='de novo' IMP biosynthetic process, 0006545=glycine biosynthetic process, 0006760=folic acid-containing compound metabolic process, 0055114=oxidation-reduction process, 0006139=nucleobase-containing compound metabolic process" "dhfr, CG14887, dihydrofolate reductase, DHFR" "IPR017925=Dihydrofolate reductase conserved site, IPR012259=Dihydrofolate reductase, IPR024072=Dihydrofolate reductase-like domain, IPR001796=Dihydrofolate reductase domain" CG14887 16-Dec-15 2015_12 ENSDARG00000004251(dhfr) YOR236W(DFR1) WBGene00007974(dhfr-1) ENSXETG00000022939() ENSMUSG00000021707(Dhfr) "ENSG00000188985,ENSG00000178700(DHFRL1)" adult stage viable FBgn0002162 l(2)Sp6b lethal (2) Sp6b http://flybase.net/reports/FBgn0002162.html gene 16-Dec-15 2015_12 lethal FBgn0069311 X-210-22 X-210-22 http://flybase.net/reports/FBgn0069311.html gene 0007399=nervous system development 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect" FBgn0032799 CG10166 http://flybase.net/reports/FBgn0032799.html protein_coding_gene 0004582=dolichyl-phosphate beta-D-mannosyltransferase activity 0006486=protein glycosylation "Dol-P-ManTase, Dolichol-phosphate mannosyltransferase, dDPM" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR001173=Glycosyltransferase 2-like" CG10166 16-Dec-15 2015_12 ENSDARG00000057011(dpm1) YPR183W(DPM1) WBGene00022044(dpm-1) ENSXETG00000012303(dpm1) ENSMUSG00000078919 ENSG00000000419(DPM1) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017578 Max Max http://flybase.net/reports/FBgn0017578.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity" "0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "max, dmax, dMax, bHLHd9, MAX, CG9648" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG9648 16-Dec-15 2015_12 ENSDARG00000024844(max) WBGene00003509(mxl-1) ENSMUSG00000059436(Max) ENSG00000125952(MAX) " embryonic stage , embryonic stage -- adult stage " " mesoderm | presumptive

, embryonic central nervous system

, posterior midgut proper primordium

, anterior midgut proper primordium

" "viable,visible,lethal,recessive,somatic clone,small body,developmental rate defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,chaeta,somatic clone,mouth hooks,anterior pupal spiracle,scutellar bristle,anterior scutellar bristle,posterior scutellar bristle,wing" FBgn0014396 tim timeless http://flybase.net/reports/FBgn0014396.html FBgn0015535 protein_coding_gene "0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0005515=protein binding" "0009649=entrainment of circadian clock, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007620=copulation, 0042306=regulation of protein import into nucleus, 0007617=mating behavior, 0071482=cellular response to light stimulus, 0007622=rhythmic behavior, 0007623=circadian rhythm, 0006606=protein import into nucleus, 0009648=photoperiodism, 0030431=sleep, 0008062=eclosion rhythm, 0045475=locomotor rhythm, 0045187=regulation of circadian sleep/wake cycle, sleep, 0060086=circadian temperature homeostasis, 0046957=negative phototaxis, 0048512=circadian behavior, 2000678=negative regulation of transcription regulatory region DNA binding, 0042749=regulation of circadian sleep/wake cycle, 0003053=circadian regulation of heart rate" "0005634=nucleus, 0005737=cytoplasm, 0043234=protein complex" "timeless1, rit, TIM, Timeless, Tim, CG3234, ritsu, tim1, dtim, dTim, TIMELESS, dtimeless, Ritsu, mel_tim, dTIM" IPR006906=Timeless protein CG3234 16-Dec-15 2015_12 " adult stage , adult stage" " ventral adult lateral neuron

, adult brain | restricted

, photoreceptor cell

, adult lateral neuron

, head

, adult head

, dorsal adult lateral neuron

" " adult stage , larval stage | third instar " " adult head

, glial cell &&of medulla | restricted

, glial cell &&of lamina | restricted

, larval lateral neuron

, neuron &&of protocerebrum

, photoreceptor cell

, neuron &&of protocerebrum | restricted

" "locomotor rhythm defective,semidominant,viable,neuroanatomy defective,circadian rhythm defective,fertile,wild-type,recessive,mating defective,semi-sterile,mating rhythm defective,photoperiod response variant,conditional,semi-fertile,sleep defective,behavior defective,visual behavior defective,stress response defective,circadian behavior defective,dominant,eclosion rhythm defective" "indirect flight muscle motor neuron MN5,posterior adult hindgut,Malpighian tubule" FBgn0052296 Mrtf Myocardin-related transcription factor http://flybase.net/reports/FBgn0052296.html "FBgn0035368, FBgn0035369" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0033613=activating transcription factor binding, 0001105=RNA polymerase II transcription coactivator activity" "0007476=imaginal disc-derived wing morphogenesis, 0007424=open tracheal system development, 0007298=border follicle cell migration, 0045893=positive regulation of transcription, DNA-templated, 0030036=actin cytoskeleton organization, 0071456=cellular response to hypoxia, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0051302=regulation of cell division, 0008078=mesodermal cell migration" "0005634=nucleus, 0005737=cytoplasm" "Mal-D, mal, CG14951, mal-d, dMrtf, CG12188, DMRTF, MAL-D, MRTF, CG32296, dMRTF" "IPR003034=SAP domain, IPR004018=RPEL repeat" CG32296 16-Dec-15 2015_12 "ENSXETG00000022963(MKL1),ENSXETG00000010993(MKL2),ENSXETG00000011035(MYOCD)" "ENSMUSG00000020542(Myocd),ENSMUSG00000042292(Mkl1),ENSMUSG00000009569" "ENSG00000186260(MKL2),ENSG00000196588(MKL1),ENSG00000141052(MYOCD)" "visible,recessive,viable,fertile,lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,female sterile,neuroanatomy defective,size defective" "presumptive embryonic/larval tracheal system,chaeta,dorsal branch primordium,ganglionic branch primordium,embryonic/larval dorsal anastomosis,dorsal trunk primordium,border follicle cell,somatic clone,follicle cell & actin filament | somatic clone,nurse cell ring canal,cell autonomous,border follicle cell & actin filament,ellipsoid body,mesoderm,cardioblast,cardiogenic mesoderm,embryonic somatic muscle,dorsal,wing,wing cell,embryonic dorsal vessel,follicle cell & actin filament | ectopicslbo.2.6,wing vein" DRSC08410 E 0.576605916 0.145201744 1.382253748 1.757396492 1.134213506 1.179685582 FBgn0030664 CG8119 http://flybase.net/reports/FBgn0030664.html protein_coding_gene 0003677=DNA binding "IPR006578=MADF domain, IPR004210=BESS motif" CG8119 16-Dec-15 2015_12 viable FBgn0001768 l(1)M38 lethal (1) M38 http://flybase.net/reports/FBgn0001768.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0030993 Mec2 Mec2 http://flybase.net/reports/FBgn0030993.html protein_coding_gene 0005515=protein binding 0097206=nephrocyte filtration "0016020=membrane, 0005917=nephrocyte diaphragm" "CG7635, DMec2" "IPR001107=Band 7 protein, IPR001972=Stomatin family" CG7635 16-Dec-15 2015_12 ENSDARG00000057035(zgc:110200) ENSXETG00000005844() "viable,fertile" "embryonic/larval pericardial cell,nephrocyte diaphragmDot.PK" FBgn0002560 Lot-1 Lot 1 http://flybase.net/reports/FBgn0002560.html gene "Lot, Lot-94, Lot1, Lo-94" 16-Dec-15 2015_12 "chemosensitive behavior defective,semidominant,recessive" FBgn0003747 Gr5a Gustatory receptor 5a http://flybase.net/reports/FBgn0003747.html "FBgn0029787, FBgn0041213" protein_coding_gene "0033041=sweet taste receptor activity, 0004930=G-protein coupled receptor activity, 0008527=taste receptor activity" "0010353=response to trehalose, 0050912=detection of chemical stimulus involved in sensory perception of taste, 0007637=proboscis extension reflex, 0050916=sensory perception of sweet taste, 0050909=sensory perception of taste" 0016021=integral component of membrane "trehalose receptor, Gustatory receptor 5a, Gr5a, Gustatory receptor LU.7, GRLU.7, tre, Gr5, Gr5A1, CG15779, GR5a, GR5A, Dmel5a, GrLU7, Trehalose-sensitivity, Tre, gustatory receptor 5a, LU.7, han, Trehalose sensitivity" IPR009318=Gustatory receptor CG15779 16-Dec-15 2015_12 WBGene00001804(gur-3) adult stage gustatory sensory organ

"taste perception defective,neurophysiology defective,proboscis extension reflex defective,recessive,feeding behavior defective,semidominant,viable" "large labellar taste bristle,labellar taste bristle" FBgn0085446 CG34417 http://flybase.net/reports/FBgn0085446.html "FBgn0046226, FBgn0029876, FBgn0029875" protein_coding_gene "0003779=actin binding, 0005200=structural constituent of cytoskeleton" 0007498=mesoderm development "0005875=microtubule associated complex, 0005856=cytoskeleton" "BcDNA:GH23906, CG3960, CG3950" "IPR022189=Smoothelin, IPR001715=Calponin homology domain" CG34417 16-Dec-15 2015_12 "viable,fertile" FBgn0003261 Rm62 Rm62 http://flybase.net/reports/FBgn0003261.html "FBgn0010736, FBgn0011038, FBgn0011355, FBgn0011356, FBgn0011496, FBgn0011645" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0004004=ATP-dependent RNA helicase activity, 0003729=mRNA binding, 0003676=nucleic acid binding" "0019730=antimicrobial humoral response, 0016246=RNA interference, 0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0050688=regulation of defense response to virus" "0005875=microtubule associated complex, 0005703=polytene chromosome puff, 0071013=catalytic step 2 spliceosome, 0005700=polytene chromosome, 0071011=precatalytic spliceosome, 0005737=cytoplasm, 0005634=nucleus" "l(3)j3D2, l(3)j3D5, l(3)01086, l(3)s5196, Helicase p62, Lip, Lighten-up, p68, rm62, 4136, l(3)rG338, dmP68, CG10279, DmRH8, Lighten up, RM62, Dmp68" "IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal" CG10279 16-Dec-15 2015_12 YNL112W(DBP2) WBGene00010260(F58E10.3) " adult stage , larval stage , embryonic stage " "lethal,recessive,viable,sterile,visible,dominant,developmental rate defective,male sterile,female sterile,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "class IV dendritic arborizing neuron,somatic clone,pigment cell,nurse cell & nuclear chromosome,egg chamber,dorsocentral bristle,scutellar bristle,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC12365 E -1.20788071 0.085471981 -2.041721811 -0.257850883 1.258657422 -0.131489913 FBgn0024248 chico chico http://flybase.net/reports/FBgn0024248.html "FBgn0013449, FBgn0014169, FBgn0028483, FBgn0043507, FBgn0043508" protein_coding_gene "0005158=insulin receptor binding, 0043548=phosphatidylinositol 3-kinase binding, 0005159=insulin-like growth factor receptor binding, 0042169=SH2 domain binding" "0050778=positive regulation of immune response, 0060250=germ-line stem-cell niche homeostasis, 0007568=aging, 0032925=regulation of activin receptor signaling pathway, 0008340=determination of adult lifespan, 0048133=male germ-line stem cell asymmetric division, 0042594=response to starvation, 0008361=regulation of cell size, 0046622=positive regulation of organ growth, 0007285=primary spermatocyte growth, 0048009=insulin-like growth factor receptor signaling pathway, 0007295=growth of a germarium-derived egg chamber, 0035159=regulation of tube length, open tracheal system, 0040018=positive regulation of multicellular organism growth, 0035264=multicellular organism growth, 0034059=response to anoxia, 0008286=insulin receptor signaling pathway, 0044237=cellular metabolic process, 0030307=positive regulation of cell growth, 0007296=vitellogenesis, 0040014=regulation of multicellular organism growth, 0045793=positive regulation of cell size, 0000902=cell morphogenesis, 0006629=lipid metabolic process, 0046620=regulation of organ growth, 0008355=olfactory learning" "0043231=intracellular membrane-bounded organelle, 0005634=nucleus, 0005737=cytoplasm" "Insulin receptor substrate, anon-WO0078940.1, BcDNA:GH11263, chic, Chico, BcDNA.GH11263, dIRS, fs(2)4, insulin-like receptor substrate, CG5686, flipper, fs(2)ry4, anon-WO0078940.4, IRS, IRS/chico, insulin receptor substrate, CHICO, unnamed" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR002404=IRS-type PTB domain" CG5686 16-Dec-15 2015_12 "ENSDARG00000060330,ENSDARG00000036414,ENSDARG00000054087,ENSDARG00000052065,ENSDARG00000037099(zgc:56306)" "ENSXETG00000020086(IRS1),ENSXETG00000001566(IRS4),ENSXETG00000002647(IRS2)" "ENSMUSG00000055980(Irs1),ENSMUSG00000038894" "ENSG00000169047(IRS1),ENSG00000185950(IRS2),ENSG00000133124(IRS4)" "small body,decreased cell number,decreased cell size,visible,partially lethal - majority die,learning defective,recessive,viable,female sterile,long lived,male semi-sterile,dominant,developmental rate defective,partially lethal - majority live,neurophysiology defective,size defective,stress response defective,female limited,neuroanatomy defective,starvation stress response defective,somatic clone,radiation sensitive,wild-type,reduced" "adult,eye,ommatidium,wing,ovary,follicle cell,egg chamber,adult heart,cell autonomous,somatic clone,head capsule,maxillary palpus,male,genital arch,larva,nurse cell,Kenyon cell,adult mushroom body,adult brain,adult gut,wing disc,embryonic/larval dorsal trunk,embryonic/larval transverse connective,larval salivary gland & nucleus,ellipsoid body,synapse,male germline stem cell,polar primary spermatocyte,primary spermatocyte" DRSC03531 I -0.081804826 2.60407301 -1.149392713 -0.693893623 0.007064413 0.855330773 FBgn0038206 twf twinfilin http://flybase.net/reports/FBgn0038206.html protein_coding_gene "0003779=actin binding, 0004713=protein tyrosine kinase activity" "0010591=regulation of lamellipodium assembly, 0030837=negative regulation of actin filament polymerization, 0030042=actin filament depolymerization, 0016319=mushroom body development, 0007298=border follicle cell migration, 0007274=neuromuscular synaptic transmission, 0008407=chaeta morphogenesis, 0048488=synaptic vesicle endocytosis" 0005737=cytoplasm "twinfillin, CG3172, A6, Twf, Twinfilin, Twinfillin" "IPR002108=Actin-depolymerising factor homology domain, IPR028458=Twinfilin, IPR029006=ADF-H/Gelsolin-like domain" CG3172 16-Dec-15 2015_12 "ENSDARG00000011661(twf1b),ENSDARG00000009727(zgc:112092)" YGR080W(TWF1) WBGene00018187(F38E9.5) "ENSXETG00000026830(ptk9),ENSXETG00000002765(TWF2)" "ENSMUSG00000022451(Twf1),ENSMUSG00000023277(Twf2)" "ENSG00000151239(TWF1),ENSG00000221814" " larval stage | third instar , pupal stage , larval stage | first instar , larval stage | second instar , embryonic stage , adult stage | female , adult stage | male " " pupal stage | 32hr , embryonic stage , oogenesis stage , larval stage " " microchaeta

,

ubiquitous , border follicle cell

, macrochaeta

, ovary

" "viable,small body,hypoactive,flightless,developmental rate defective,visible,neuroanatomy defective,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage" "macrochaeta,ommatidium,interommatidial bristle,microchaeta,trichome,actin filament[-],chaeta,adult mushroom body,mushroom body beta-lobe,mushroom body alpha-lobe,border follicle cell,heat sensitive,trichogen cell,supernumerary,somatic clone,NMJ bouton" FBgn0065128 l(3)SH137 lethal (3) SH137 http://flybase.net/reports/FBgn0065128.html gene l(2)SH3 137 16-Dec-15 2015_12 "lethal,recessive" FBgn0001671 l(1)EN8 lethal (1) from Eugene Nonautonomous 8 http://flybase.net/reports/FBgn0001671.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive,lethal - all die before end of larval stage,some die during larval stage" "egg chamber,germline clone,maternal effect,fat body,Malpighian tubule,embryonic/larval salivary gland,adult cuticle" FBgn0039450 CG5484 http://flybase.net/reports/FBgn0039450.html FBgn0062065 protein_coding_gene "0009306=protein secretion, 0048812=neuron projection morphogenesis, 0000902=cell morphogenesis" "COP, anon-WO0118547.366" IPR005578=Yif1 family CG5484 16-Dec-15 2015_12 "ENSDARG00000040505(zgc:103562),ENSDARG00000019636(zgc:73136)" YNL263C(YIF1) WBGene00010178(yif-1) ENSXETG00000000151(yif1b) "ENSMUSG00000030588(Yif1b),ENSMUSG00000024875(Yif1a)" "ENSG00000167645(YIF1B),ENSG00000174851(YIF1A)" lethal FBgn0002526 LanA Laminin A http://flybase.net/reports/FBgn0002526.html FBgn0015948 protein_coding_gene 0005102=receptor binding "0007422=peripheral nervous system development, 0009887=organ morphogenesis, 0007417=central nervous system development, 0007507=heart development, 0007498=mesoderm development, 0009888=tissue development, 0007476=imaginal disc-derived wing morphogenesis, 0034446=substrate adhesion-dependent cell spreading, 0007411=axon guidance, 0033627=cell adhesion mediated by integrin, 0002121=inter-male aggressive behavior, 0035001=dorsal trunk growth, open tracheal system, 0035011=melanotic encapsulation of foreign target, 0031987=locomotion involved in locomotory behavior, 0045995=regulation of embryonic development, 0030334=regulation of cell migration, 0030155=regulation of cell adhesion, 0048598=embryonic morphogenesis, 0001964=startle response, 0016321=female meiosis chromosome segregation, 0048854=brain morphogenesis, 0045886=negative regulation of synaptic growth at neuromuscular junction" "0005604=basement membrane, 0036062=presynaptic periactive zone, 0005605=basal lamina" "alpha[[3,5]], laminin A chain, Lam, Laminin alpha3,5, Lam-A, FBgn0002526, laminin A, CG10236, lamininA, hdln, FBtr0077014, Laminin A5, alpha3/5, laminin alpha-chain, Laminin, laminin A subunit, lamA, laminin alpha, LamininA, CT28769, LM-A/alpha1, LamA, laminin alpha[[3,5]], headline, laminin, laminin alpha3/5, lanA, Lan, alpha3,5 laminin, laminin alpha3,5" "IPR013032=EGF-like, conserved site, IPR009254=Laminin alpha, domain I, IPR002049=Laminin EGF domain, IPR000034=Laminin IV, IPR010307=Laminin domain II, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR008211=Laminin, N-terminal" CG10236 16-Dec-15 2015_12 ENSDARG00000058543(lama5) WBGene00001328(epi-1) ENSXETG00000002008(LAMA5) ENSMUSG00000015647(Lama5) ENSG00000130702(LAMA5) " embryonic stage , embryonic stage | stage >12 , embryonic stage | late , embryonic stage | stage 11-12 " " somatic mesoderm

, interface glial cell

, glial cell | lateral

, embryonic brain

, hemocyte

, head mesoderm

, visceral mesoderm

, embryonic/larval fat body

, ventral nerve cord

, sense organ

, embryonic/larval midgut

, ectoderm

, ventral midline

" " embryonic stage , embryonic stage | stage 13-15 , embryonic stage | 10-13 hr " " ventral nerve cord

, neuropil associated CNS glial cell

, intersegmental nerve

, embryonic midgut

, embryonic brain

, epidermis

, embryonic/larval digestive system

, myoblast &&of larval muscle system

, embryonic spiracle

, segmental nerve

, hemocyte

, larval muscle system

, glial cell

, embryonic/larval fat body

" "lethal,behavior defective,recessive,viable,neuroanatomy defective,immune response defective,meiotic cell cycle defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,eye photoreceptor cell & axon,embryonic/larval optic stalk,optic nerve,glial cell,neuromuscular junction | third instar larval stageC57,macrochaeta,anterior fascicle & synapse,intersegmental nerve,embryonic/larval somatic muscle,embryonic/larval pericardial cell,abdominal 1 ventral oblique muscle 4,abdominal 2 ventral oblique muscle 4,abdominal 3 ventral oblique muscle 4,abdominal 4 ventral oblique muscle 4,abdominal 5 ventral oblique muscle 4,abdominal 6 ventral oblique muscle 4,abdominal 7 ventral oblique muscle 4,abdominal 1 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 5,abdominal 3 ventral oblique muscle 5,abdominal 4 ventral oblique muscle 5,abdominal 5 ventral oblique muscle 5,abdominal 6 ventral oblique muscle 5,abdominal 7 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 6,abdominal 3 ventral oblique muscle 6,abdominal 4 ventral oblique muscle 6,abdominal 5 ventral oblique muscle 6,abdominal 6 ventral oblique muscle 6,abdominal 7 ventral oblique muscle 6,abdominal 1 ventral acute muscle 3,abdominal 2 ventral acute muscle 3,abdominal 3 ventral acute muscle 3,abdominal 4 ventral acute muscle 3,abdominal 5 ventral acute muscle 3,abdominal 6 ventral acute muscle 3,abdominal 7 ventral acute muscle 3,embryonic/larval midgut & endoderm,fascicle,embryo,egg chamber,germline clone,oocyte nucleus,cell non-autonomous,somatic clone,muscle attachment site & basal lamina,bouton & neuromuscular junction & embryo,amnioserosa,dorsal superficial trachea,extracellular matrix,neuromuscular junction | third instar larval stage, with LanAGD6022, C57,embryonic/larval proventriculus,embryonic/larval midgut,embryonic head,ocellar nerve & axon,eye,leg,wing,antenna,ocellus,postvertical bristle,ocellar bristle,ommatidial precursor cluster,cone cell,eye photoreceptor cell,ocellar nerve,embryonic/larval dorsal vessel,germline cell,neuromuscular junction | third instar larval stage, with LanA9-32, C57" FBgn0037363 Atg17 Autophagy-related 17 http://flybase.net/reports/FBgn0037363.html protein_coding_gene 0019887=protein kinase regulator activity "0001934=positive regulation of protein phosphorylation, 0035071=salivary gland cell autophagic cell death, 0016236=macroautophagy, 0035096=larval midgut cell programmed cell death, 1902350=cellular response to chloroquine, 0032147=activation of protein kinase activity, 0006914=autophagy" "0034273=ATG1/UKL1 signaling complex, 0000407=pre-autophagosomal structure" "Autophagy-specific gene 17, CG1347, FIP200, fip200, RB1CC1, Fip200" IPR019460=Autophagy-related protein 11 CG1347 16-Dec-15 2015_12 WBGene00020334(atg-11) ENSMUSG00000025907(Rb1cc1) ENSG00000023287(RB1CC1) "viable,lethal,heat sensitive,locomotor behavior defective,flightless,visible,neuroanatomy defective,short lived,developmental rate defective,RU486 conditional,majority die during pharate adult stage,uncoordinated,starvation stress response defective,lethal - all die during pharate adult stage" "wing,autophagic vacuole,optic lobe,major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16,autophagic vacuole | third instar larval stage,embryonic/larval fat body,embryonic/larval salivary gland" FBgn0035411 Girdin Girdin http://flybase.net/reports/FBgn0035411.html protein_coding_gene "0090136=epithelial cell-cell adhesion, 0045793=positive regulation of cell size, 0090132=epithelium migration, 0007015=actin filament organization" "0005915=zonula adherens, 0005737=cytoplasm, 0005914=spot adherens junction" "CG12734, dGirdin" IPR008636=Hook-related protein family CG12734 16-Dec-15 2015_12 ENSDARG00000009363(LOC553231) WBGene00013082(Y51A2D.15) "ENSXETG00000015797(CCDC88C),ENSXETG00000004516(CCDC88A)" "ENSMUSG00000021182(Ccdc88c),ENSMUSG00000032740(Ccdc88a)" "ENSG00000015133(CCDC88C),ENSG00000115355(CCDC88A)" "decreased cell number,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,viable,decreased cell size" "wing,posterior,wing vein" FBgn0035281 Cpr62Bc Cuticular protein 62Bc http://flybase.net/reports/FBgn0035281.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" 0040003=chitin-based cuticle development 0031012=extracellular matrix "CG1919, DmelCpr62Bc" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG1919 16-Dec-15 2015_12 viable FBgn0000748 fs(1)A331 female sterile (1) A331 http://flybase.net/reports/FBgn0000748.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,non-rescuable maternal effect" FBgn0031005 Hs3st-B Heparan sulfate 3-O sulfotransferase-B http://flybase.net/reports/FBgn0031005.html protein_coding_gene 0008467=[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity "0007219=Notch signaling pathway, 0007474=imaginal disc-derived wing vein specification, 0048190=wing disc dorsal/ventral pattern formation, 0016348=imaginal disc-derived leg joint morphogenesis, 0008586=imaginal disc-derived wing vein morphogenesis, 0051036=regulation of endosome size, 0007032=endosome organization, 0007040=lysosome organization, 0007476=imaginal disc-derived wing morphogenesis, 0001745=compound eye morphogenesis, 0008587=imaginal disc-derived wing margin morphogenesis, 0008407=chaeta morphogenesis, 0050768=negative regulation of neurogenesis" "CG7890, 3-O-sulfotransferase, dHs3st-B, dHS3OSTB" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000863=Sulfotransferase domain" CG7890 16-Dec-15 2015_12 "ENSDARG00000060253(hs3st3b1b),ENSDARG00000059594(hs3st3b1a),ENSDARG00000059948(LOC797517),ENSDARG00000052648(hs3st4),ENSDARG00000059616(hs3st2),ENSDARG00000059903(hs3st3l)" WBGene00044303(hst-3.2) "ENSXETG00000012409(HS3ST4),ENSXETG00000019581(),ENSXETG00000009233(),ENSXETG00000007214(HS3ST6)" "ENSMUSG00000047759(Hs3st3a1),ENSMUSG00000070407(Hs3st3b1),ENSMUSG00000078591(Hs3st4),ENSMUSG00000039628(Hs3st6),ENSMUSG00000046321(Hs3st2)" "ENSG00000153976(HS3ST3A1),ENSG00000125430(HS3ST3B1),ENSG00000182601(HS3ST4),ENSG00000162040(HS3ST6),ENSG00000122254(HS3ST2)" "visible,lethal" "eye,ommatidium,interommatidial bristle,mesothoracic tergum,macrochaeta,supernumerary,wing,anterior crossvein,wing vein L3,campaniform sensillum of anterior crossvein,sensillum campaniformium of dorsal radius,wing margin,sternopleural bristle,leg sensillum,tarsal segment,endosomedpp.blk1,lysosomedpp.blk1,anterior scutellar bristle,posterior scutellar bristle" FBgn0039802 dj-1ë_ dj-1ë_ http://flybase.net/reports/FBgn0039802.html protein_coding_gene "0008344=adult locomotory behavior, 0042775=mitochondrial ATP synthesis coupled electron transport, 0046626=regulation of insulin receptor signaling pathway, 0070301=cellular response to hydrogen peroxide, 0006979=response to oxidative stress, 0048640=negative regulation of developmental growth" "DJ-1beta, DJ-1b, DJ-1B, dj-1beta, DJ-1, CG1349" "IPR029062=Class I glutamine amidotransferase-like, IPR006287=DJ-1, IPR002818=DJ-1/PfpI" CG1349 16-Dec-15 2015_12 ENSDARG00000034826(park7) "WBGene00015184(djr-1.1),WBGene00016789(djr-1.2)" ENSXETG00000006018(park7) ENSMUSG00000028964(Park7) ENSG00000116288(PARK7) "stress response defective,short lived,locomotor behavior defective,viable,fertile,chemical sensitive,chemical resistant,long lived,recessive,oxidative stress response defective,radiation sensitive" "dopaminergic neuron,mitochondrion,dorso-lateral dopaminergic neuron,embryonic/larval brain" FBgn0010292 bys by S6 http://flybase.net/reports/FBgn0010292.html protein_coding_gene 0022008=neurogenesis 0005634=nucleus "Bystin, bystin, CG1430" IPR007955=Bystin CG1430 16-Dec-15 2015_12 ENSDARG00000001057(bysl) YBR247C(ENP1) WBGene00000276(byn-1) ENSXETG00000011846(Q5EB24_XENTR) ENSG00000112578(BYSL) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0070055 2L-144-32 2L-144-32 http://flybase.net/reports/FBgn0070055.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0002736 mago mago nashi http://flybase.net/reports/FBgn0002736.html FBgn0002095 protein_coding_gene 0005515=protein binding "0007318=pole plasm protein localization, 0046594=maintenance of pole plasm mRNA location, 0045451=pole plasm oskar mRNA localization, 0007317=regulation of pole plasm oskar mRNA localization, 0000226=microtubule cytoskeleton organization, 0008103=oocyte microtubule cytoskeleton polarization, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007173=epidermal growth factor receptor signaling pathway, 0048477=oogenesis, 0000335=negative regulation of transposition, DNA-mediated, 0008380=RNA splicing, 0007315=pole plasm assembly, 0016325=oocyte microtubule cytoskeleton organization, 0007309=oocyte axis specification, 0007267=cell-cell signaling, 0006406=mRNA export from nucleus, 0046579=positive regulation of Ras protein signal transduction, 0008104=protein localization, 0000398=mRNA splicing, via spliceosome" "0045495=pole plasm, 0005737=cytoplasm, 0071011=precatalytic spliceosome, 0035145=exon-exon junction complex, 0005634=nucleus, 0071013=catalytic step 2 spliceosome" "mago-nashi, MAGOH, DmMago, MGN, Mago, Dm MGN, Mago nashi, Mago Nashi, l(2)57Ca, CG9401, mago nishi, mgn, Magoh" IPR004023=Mago nashi protein CG9401 16-Dec-15 2015_12 ENSDARG00000038635(magoh) WBGene00003123(mag-1) ENSXETG00000008072() "ENSMUSG00000030188(Magohb),ENSMUSG00000028609(Magoh)" "ENSG00000111196(MAGOHB),ENSG00000162385(MAGOH)" " embryonic stage -- adult stage , embryonic stage | early , adult stage && oogenesis stage " "

ubiquitous , oocyte

, nurse cell

" "lethal,recessive,wild-type,viable,lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage,cell growth defective,female sterile,male sterile,visible,cold sensitive,sterile,body color defective,partially lethal - majority die,some die during pupal stage" "fusome | germline clone,oocyte nucleus,germline clone,egg,follicle cell,microtubule & oocyte,dorsal appendage,egg operculum,micropyle,posterior aeropyle,egg chamber,microtubule & egg chamber,mesothoracic tergum" DRSC04703 IEK 2.104579471 0.751532075 2.493704351 1.279685665 0.010062666 -2.253576783 FBgn0260571 MENE-Z33 http://flybase.net/reports/FBgn0260571.html gene 16-Dec-15 2015_12 "eye disc,somatic clone" FBgn0001058 Fs(3)Kun Female sterile (3) Kun http://flybase.net/reports/FBgn0001058.html gene "Fs(3)Sz17, Kan" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0003598 Su(var)3-7 Suppressor of variegation 3-7 http://flybase.net/reports/FBgn0003598.html protein_coding_gene "0003677=DNA binding, 0003682=chromatin binding, 0005515=protein binding" "0009047=dosage compensation by hyperactivation of X chromosome, 0090053=positive regulation of chromatin silencing at centromere, 0031453=positive regulation of heterochromatin assembly" "0005701=polytene chromosome chromocenter, 0000792=heterochromatin, 0005634=nucleus, 0005721=pericentric heterochromatin, 0000775=chromosome, centromeric region" "Su(Var)3-7, l(3)87El, Su(var)(3)7, DmSu(var)3-7, CG8599, SU(VAR)3-7, Su-var(3)7, Suvar(3)7, Su(var)(3)3" "IPR004210=BESS motif, IPR015880=Zinc finger, C2H2-like" CG8599 16-Dec-15 2015_12 "endomitotic cell cycle defective,lethal - all die before end of second instar larval stage,recessive,rescuable maternal effect,some die during second instar larval stage,enhancer of variegation,non-enhancer of variegation,lethal,suppressor of variegation,wild-type,dominant,viable,lethal - all die before end of larval stage,maternal effect,some die during larval stage,fertile,non-suppressor of variegation" "prothoracic gland,polytene chromosome | male3-77.1A.5'), with Su(var)3-77.1A.3',polytene chromosome | male3-77.1A.mid), with Su(var)3-77.1A.3',adult cuticle & abdomen3-79.5'),macrochaeta,humeral bristle,sex comb,ommatidium,wing,polytene chromosome chromocenter, with Su(var)3-714.3', Su(var)3-714.5'/Su(var)3-79.5',polytene chromosome | male3-714.5'),polytene chromosome chromocenter3-714.5'),polytene chromosome chromocenter, with Su(var)3-79.3', Su(var)3-714.5'/Su(var)3-79.5',polytene chromosome | male, with Su(var)3-77.1A.5'/Su(var)3-77.1A.mid,polytene chromosome | male3-714.3'),polytene chromosome chromocenter3-714.3'),polytene chromosome chromocenter3-79.5'), with Su(var)3-714.3', Su(var)3-79.3',adult cuticle & abdomen3-79.3'),polytene chromosome chromocenter3-714.5'), with Su(var)3-714.3', Su(var)3-79.3'" FBgn0060982 l(3)S028310 lethal (3) S028310 http://flybase.net/reports/FBgn0060982.html gene 0283/10 16-Dec-15 2015_12 "lethal,recessive" FBgn0283477 SF2 Splicing factor 2 http://flybase.net/reports/FBgn0283477.html "FBgn0040284, FBgn0038417, FBgn0017543" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0005515=protein binding, 0003677=DNA binding" "0006376=mRNA splice site selection, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0022008=neurogenesis, 0010468=regulation of gene expression, 0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007095=mitotic G2 DNA damage checkpoint, 0031440=regulation of mRNA 3'-end processing" "0071011=precatalytic spliceosome, 0005634=nucleus, 0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome" "dSF2/ASF, cg6987, ASF, ASF/SF2, SRp30, SF2, dSRp30, CG6987, 154911_at, dASF, dmSF2/p28" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG6987 16-Dec-15 2015_12 "ENSDARG00000057691(srsf1a),ENSDARG00000017843(srsf1b)" WBGene00004700(rsp-3) ENSXETG00000008954(BC075558.1) ENSMUSG00000018379(Srsf1) ENSG00000136450(SRSF1) "lethal - all die before end of pupal stage,some die during pupal stage,visible,heat sensitive,lethal,neuroanatomy defective" "retina,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell" DRSC16845 IE 1.692370139 0.360222202 -6.698922673 2.744157998 0.520519211 -1.096605845 FBgn0038542 TyrR Tyramine receptor http://flybase.net/reports/FBgn0038542.html "FBgn0046504, FBgn0046505" protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0008226=tyramine receptor activity" "0007211=octopamine or tyramine signaling pathway, 0071418=cellular response to amine stimulus, 1900738=positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0071928=tyramine signaling pathway" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "CG7431, anon-WO0170980.83, DrmTR, anon-WO0170980.82, DmCG7431, tyramine receptor, TR" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000276=G protein-coupled receptor, rhodopsin-like" CG7431 16-Dec-15 2015_12 ENSMUSG00000027335(Adra1d) "viable,visible,fertile" trichogen cell FBgn0262710 ifm(2)RS3 http://flybase.net/reports/FBgn0262710.html gene "0007527=adult somatic muscle development, 0060361=flight" 16-Dec-15 2015_12 "flightless,recessive" dorsal medial muscle FBgn0027375 RecQ5 RecQ5 helicase http://flybase.net/reports/FBgn0027375.html "FBgn0024312, FBgn0027689" protein_coding_gene "0003924=GTPase activity, 0004003=ATP-dependent DNA helicase activity, 0005524=ATP binding, 0017116=single-stranded DNA-dependent ATP-dependent DNA helicase activity, 0003676=nucleic acid binding, 0005525=GTP binding, 0003678=DNA helicase activity, 0004386=helicase activity" "0000070=mitotic sister chromatid segregation, 0010165=response to X-ray, 0045002=double-strand break repair via single-strand annealing, 0006974=cellular response to DNA damage stimulus, 0045930=negative regulation of mitotic cell cycle, 0006310=DNA recombination" 0005634=nucleus "DQ1, RECQE, RECQ5/QE, dmRecQ5b, CG4879, DmRECQ5, RECQ5, anon-EST:Posey293, Q1, Dm RECQ5/QE, Drosophila homolog of RecQ, dRecQ5, Dq1, homolog of RecQ" "IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain, IPR004589=DNA helicase, ATP-dependent, RecQ type, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG4879 16-Dec-15 2015_12 WBGene00004322(rcq-5) ENSXETG00000018302(wrn) ENSMUSG00000020752(Recql5) ENSG00000108469(RECQL5) " adult stage && oogenesis stage | stage S10 , embryonic stage | early , adult stage && oogenesis stage | stage S11,12 , embryonic stage -- adult stage " " nurse cell

,

ubiquitous , oocyte

" "viable,fertile,developmental rate defective,radiation sensitive,DNA repair defective,mitotic cell cycle defective,maternal effect" "nucleus | maternal effect,embryo,maternal effect,centrosome | maternal effect,eye,ommatidial precursor cluster,interommatidial bristle" FBgn0039147 CG10694 http://flybase.net/reports/FBgn0039147.html protein_coding_gene 0003684=damaged DNA binding "0006284=base-excision repair, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006289=nucleotide-excision repair" 0005634=nucleus "IPR004806=UV excision repair protein Rad23, IPR000626=Ubiquitin domain, IPR015940=Ubiquitin-associated domain, IPR009060=UBA-like, IPR029071=Ubiquitin-related domain, IPR015360=XPC-binding domain" CG10694 16-Dec-15 2015_12 viable FBgn0085224 CG34195 http://flybase.net/reports/FBgn0085224.html protein_coding_gene CG4989 "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR026113=Methyltransferase-like" CG34195 16-Dec-15 2015_12 ENSDARG00000070085(mettl6) WBGene00014205(ZK1058.5) ENSXETG00000012544(METTL6) ENSMUSG00000021891(Mettl6) ENSG00000206562(METTL6) "viable,fertile" FBgn0027567 CG8108 http://flybase.net/reports/FBgn0027567.html protein_coding_gene 0046427=positive regulation of JAK-STAT cascade BcDNA:GH07921 "IPR015880=Zinc finger, C2H2-like, IPR026811=Cip1-interacting zinc finger protein" CG8108 16-Dec-15 2015_12 ENSG00000148337(CIZ1) "lethal - all die before end of pupal stage,some die during pupal stage,female sterile" DRSC09675 IK 9.333957591 5.168792171 0.247770702 -0.78093577 1.181377442 2.623217742 FBgn0000166 bcd bicoid http://flybase.net/reports/FBgn0000166.html "FBgn0040059, FBgn0014130, FBgn0014131, FBgn0015909, FBgn0015910, FBgn0015911, FBgn0015912" protein_coding_gene "0005515=protein binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0030371=translation repressor activity, 0045182=translation regulator activity, 0016015=morphogen activity, 0043565=sequence-specific DNA binding, 0003730=mRNA 3'-UTR binding, 0003700=sequence-specific DNA binding transcription factor activity" "0008595=anterior/posterior axis specification, embryo, 0006417=regulation of translation, 0017148=negative regulation of translation, 0006355=regulation of transcription, DNA-templated, 0007355=anterior region determination, 0009948=anterior/posterior axis specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008358=maternal determination of anterior/posterior axis, embryo, 0048477=oogenesis, 0007367=segment polarity determination, 0006357=regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "BICOID, BG:DS00276.7, BCD, mum, CG1034, Bicoid, PRD gene 4, multimorph, bcd, prd4, bicoid, bic, Bcd" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG1034 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage S5-7 , adult stage && oogenesis stage , embryonic stage | stage 4 , embryonic stage | stage 1-2 , oogenesis stage , oogenesis stage | stage S10 , embryonic stage , embryonic stage | 0-3 hr , embryonic stage | early , embryonic stage | stage 3-4 , oogenesis stage | stage S10B , adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage | stage S13-14 , embryonic stage | 0-2 hr , embryonic stage | 2-4 hr , embryonic stage | stage <5 " " oocyte | anterior

, nurse cell

{ $ exu* } , nurse cell

,

90-100% egg length ,

anterior , ovary

, organism | 80-100% egg length

, ovary

{ $ swa* } , organism

,

{ $ swa* } , ovary

{ 0 stau* } ,

{ $ stau* } ,

{ $ exu* } , organism | anterior posterior gradient

, oocyte

" " embryonic stage | stage 1-5 , embryonic stage | 0-3.25 hr , embryonic stage | stage 4 , embryonic stage | early , embryonic stage | stage 4-6 " "

20-100% egg length , organism

,

anterior posterior gradient ,

anterior ,

70-100% egg length , organism | 90-100% egg length

" "wild-type,lethal,male,visible,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female,increased cell death,homeotic,sterile,female sterile,recessive,partially lethal - majority die,germline clone,non-rescuable maternal effect,heat sensitive" "embryo,anterior,organism,maternal effect,larval head,syncytial blastoderm embryo,wing,female,wing pouch,cephalic furrow,labral segment,head,embryonic/first instar larval cuticle,embryonic/larval cuticle,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,denticle belt,cephalopharyngeal skeleton,presumptive embryonic/larval peripheral nervous system,embryonic neuroblast & abdomen,larval thorax,ocular segment,telson,embryonic thoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,embryonic gnathal segment,mouth hooks,median tooth,dorsal closure embryo,gonadal sheath proper primordium,germline cell,embryonic/larval posterior spiracle,ectopic,embryonic thorax,embryonic head,embryonic abdomen,embryonic/larval salivary gland,pole cell,extended germ band embryo,embryonic/larval spiracle,embryonic head segment,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,terminalia,abdomen,filzkorper,thorax,germline clone,embryonic abdominal segment,posterior,abdominal segment 7,abdominal segment 8,abdominal segment 9,embryonic/larval midgut,lateral process,dorsal bridge,embryonic/larval pharynx" FBgn0022786 Hira Hira http://flybase.net/reports/FBgn0022786.html FBgn0027940 protein_coding_gene "0003682=chromatin binding, 0003714=transcription corepressor activity" "0006338=chromatin remodeling, 0035041=sperm chromatin decondensation, 0035042=fertilization, exchange of chromosomal proteins, 0006336=DNA replication-independent nucleosome assembly, 0006355=regulation of transcription, DNA-templated" "0001673=male germ cell nucleus, 0042585=germinal vesicle, 0005634=nucleus" "sesame, dHira, Drosophila hira homolog, Drosophila homolog of HIRA, hira, HIRA, dhira, ssm, CG12153, Dhh" "IPR001680=WD40 repeat, IPR011494=TUP1-like enhancer of split, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019015=HIRA B motif, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR031120=WD repeat HIR1" CG12153 16-Dec-15 2015_12 ENSDARG00000013434(hira) WBGene00019627(K10D2.1) ENSMUSG00000022702(Hira) ENSG00000100084(HIRA) " adult stage | female , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | early " " ovary

, oocyte

, nurse cell

" "partially lethal - majority die,paternal effect,recessive,some die during embryonic stage,lethal - all die before end of embryonic stage,non-rescuable maternal effect,enhancer of variegation,non-enhancer of variegation,female sterile,viable,male fertile,maternal effect" "male pronucleus,male pronucleus | non-rescuable maternal effect,male pronucleus & nuclear membrane | non-rescuable maternal effect,embryonic/first instar larval cuticle,maternal effect,cephalopharyngeal skeleton,male pronucleus | maternal effect,mitotic cell cycle | maternal effect,male pronucleus | maternal effectct4b1)" FBgn0014338 lphA larval photokinesis A http://flybase.net/reports/FBgn0014338.html gene "0009416=response to light stimulus, 0030537=larval behavior, 0007632=visual behavior" 16-Dec-15 2015_12 "visual behavior defective,behavior defective" FBgn0003963 ush u-shaped http://flybase.net/reports/FBgn0003963.html protein_coding_gene "0008134=transcription factor binding, 0046872=metal ion binding, 0005515=protein binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0001102=RNA polymerase II activating transcription factor binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0007391=dorsal closure, 0006355=regulation of transcription, DNA-templated, 0008258=head involution, 0007393=dorsal closure, leading edge cell fate determination, 0030097=hemopoiesis, 0042440=pigment metabolic process, 0007507=heart development, 0022416=chaeta development, 0008293=torso signaling pathway, 0043433=negative regulation of sequence-specific DNA binding transcription factor activity, 0007398=ectoderm development, 0002805=regulation of antimicrobial peptide biosynthetic process, 0035167=larval lymph gland hemopoiesis, 0048749=compound eye development, 0009996=negative regulation of cell fate specification, 0042690=negative regulation of crystal cell differentiation, 0007362=terminal region determination, 0048542=lymph gland development, 0046665=amnioserosa maintenance, 0007390=germ-band shortening" 0005634=nucleus "U-shaped, u-sh, Drosophila Friend of GATA, Ush, ZFPM2, FOG, l(2)19, ushaped, CG2762, Friend of GATA, dFOG" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG2762 16-Dec-15 2015_12 "ENSDARG00000040123,ENSDARG00000035997(zfpm2b),ENSDARG00000041572(zfpm1)" "ENSMUSG00000049577(Zfpm1),ENSMUSG00000022306(Zfpm2)" "ENSG00000179588(ZFPM1),ENSG00000169946(ZFPM2)" " larval stage | third instar , embryonic stage | 4-8 hr , embryonic stage | stage 6 , larval stage | third instar stage 2 , pupal stage && adult stage " " dorsal ectoderm anlage

, imaginal disc | restricted

" "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,wild-type,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority live,lethal - all die before end of P-stage,some die during pharate adult stage,visible,recessive,heat sensitive,hyperplasia,decreased cell number,increased cell number,lethal,dominant,planar polarity defective,partially lethal - majority die,some die during pupal stage,size defective,lethal - all die before end of pupal stage" "adult thorax,posterior scutellar bristle | adult stage,anterior scutellar bristle | adult stage,posterior dorsocentral bristle | adult stage,anterior dorsocentral bristle | adult stage,anterior postalar bristle | adult stage,posterior supraalar bristle | adult stage,anterior supraalar bristle | adult stage,presutural bristle | adult stage,posterior notopleural bristle | adult stage,anterior notopleural bristle | adult stage,direct flight muscle,dorsal medial muscle,dorsocentral bristle,postvertical bristle,scutellar bristle,adult external thorax,heat sensitive,cardioblast,ectopic,pericardial cell,mesoderm,crystal cell,extended germ band embryo,dorsal closure embryo,embryonic head,cephalopharyngeal skeleton,dorsal bridge,vertical bridge,cuticle,filzkorper,amnioserosa,cell non-autonomous,somatic clone,dorsocentral bristle & axon,plasmatocyte,embryonic/larval lymph gland,lamellocyte,hemocyte,scutellum,dorsal,epidermis,anterior,posterior,crystal cell | embryonic stage,precursor,fat body,eye disc,eye,antenna,ommatidium,heart primordium,plasmatocyte | third instar larval stage,posterior signalling centre of lymph gland primary lobe,chorion,drug conditional,lamellocyte | third instar larval stage,hemocyte | third instar larval stage,embryonic/larval lymph gland | second instar larval stage" DRSC00843 IE 2.858683153 5.566237244 3.627907376 -0.632702047 -1.496566144 0.077487084 FBgn0003044 Pcl Polycomblike http://flybase.net/reports/FBgn0003044.html FBgn0010678 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003682=chromatin binding, 0035064=methylated histone binding, 0008270=zinc ion binding, 0005515=protein binding" "0045892=negative regulation of transcription, DNA-templated, 0050832=defense response to fungus, 0022008=neurogenesis" "0005634=nucleus, 0035098=ESC/E(Z) complex" "PCL, l(2)s1859, CG5109, pcl, Polycomb-like" "IPR019787=Zinc finger, PHD-finger, IPR025894=Polycomb-like MTF2 factor 2, C-terminal domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR002999=Tudor domain" CG5109 16-Dec-15 2015_12 ENSDARG00000005590(mtf2) "ENSXETG00000023001(mtf2),ENSXETG00000020362(PHF1)" "ENSMUSG00000029267(Mtf2),ENSMUSG00000026873(Phf19),ENSMUSG00000024193(Phf1)" "ENSG00000143033(MTF2),ENSG00000119403(PHF19),ENSG00000112511(PHF1)" embryonic stage

ubiquitous larval stage larval salivary gland

"visible,dominant,homeotic,non-suppressor of variegation,non-enhancer of variegation,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,immune response defective,lethal,wild-type,viable,suppressor of variegation,somatic clone,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "sex comb,ectopic,mesothoracic leg,metathoracic leg,mesothoracic leg & sex comb | ectopic,hemocyte,plasmatocyte,crystal cell,wing,prothoracic leg,adult abdominal segment 4,antenna,wing vein L5,anterior compartment,posterior compartment,metathoracic metatarsus,metathoracic coxa,metathoracic trochanter,metathoracic femur,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,female accessory gland,midgut constriction,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval abdominal segment 7,larval abdominal segment 8,germline clone,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,adult abdominal segment 2,somatic clone,adult abdominal segment 3,adult abdominal segment 5,adult abdominal segment 6,male,embryonic/larval neuroblast,ganglion mother cell" FBgn0025352 Thiolase Thiolase http://flybase.net/reports/FBgn0025352.html FBgn0010464 protein_coding_gene "0016509=long-chain-3-hydroxyacyl-CoA dehydrogenase activity, 0003988=acetyl-CoA C-acyltransferase activity" "0008340=determination of adult lifespan, 0006635=fatty acid beta-oxidation" "0005875=microtubule associated complex, 0016507=mitochondrial fatty acid beta-oxidation multienzyme complex, 0005739=mitochondrion, 0005811=lipid particle" "thiolase, unnamed, l(2)k09828, ACoT, CG4581, Mtpbeta" "IPR020610=Thiolase, active site, IPR020615=Thiolase, acyl-enzyme intermediate active site, IPR002155=Thiolase, IPR016039=Thiolase-like, IPR020616=Thiolase, N-terminal, IPR020613=Thiolase, conserved site, IPR020617=Thiolase, C-terminal" CG4581 16-Dec-15 2015_12 ENSDARG00000057147 WBGene00015125(B0303.3) ENSXETG00000003203(hadhb) ENSMUSG00000059447(Hadhb) ENSG00000138029(HADHB) "lethal,recessive,viable,fertile,short lived,locomotor behavior defective" "eye photoreceptor cell,cell autonomous,somatic clone,adult fat body,lipid particle" FBgn0002677 mat(2)syn-E maternal effect syncytial blastoderm arrest E http://flybase.net/reports/FBgn0002677.html gene "0007279=pole cell formation, 0007349=cellularization" "mat(2)synPJ50, PJ60" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0004587 B52 B52 http://flybase.net/reports/FBgn0004587.html "FBgn0004424, FBgn0010262, FBgn0011022, FBgn0013330" protein_coding_gene "0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0048024=regulation of mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0031440=regulation of mRNA 3'-end processing, 0000398=mRNA splicing, via spliceosome, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0010468=regulation of gene expression, 0007067=mitotic nuclear division, 0006376=mRNA splice site selection" "0005634=nucleus, 0071011=precatalytic spliceosome, 0035327=transcriptionally active chromatin, 0016607=nuclear speck, 0071013=catalytic step 2 spliceosome, 0005700=polytene chromosome, 0035062=omega speckle" "RNA-binding protein 8, MabB52, B52/dSRp55, CG10851, l(3)s2249, RRM8, Rbp8, RSp55, E726, Splicing factor B52, rrm8, E(Dfd), serine-arginine protein 55, dSRp55, SRp55, Monoclonal-antibody-B52, Serine/arginine rich protein 55, B52/SRp55, SR55, Enhancer of Deformed" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10851 16-Dec-15 2015_12 "ENSDARG00000016783(srsf6b),ENSDARG00000013729(srsf6a),ENSDARG00000009287" WBGene00004698(rsp-1) "ENSXETG00000025503(sfrs6),ENSXETG00000014380(SFRS4)" ENSMUSG00000016921(Srsf6) "ENSG00000124193(SRSF6),ENSG00000116350(SRSF4)" "lethal,recessive,eye color defective,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "pigment cell,sternite,macrochaeta,wing,sternopleural bristle,adult salivary gland,retina,eye,embryonic/larval salivary gland,embryonic/larval brain,trichogen cell,mesothoracic tergum" FBgn0001763 l(1)M22 lethal (1) M22 http://flybase.net/reports/FBgn0001763.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003696 thi thickhead http://flybase.net/reports/FBgn0003696.html gene thick head 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" embryonic head FBgn0020773 vid visual system disorganizer http://flybase.net/reports/FBgn0020773.html gene 16-Dec-15 2015_12 "optic lobe,somatic clone,eye photoreceptor cell,adult brain,ommatidium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,pigment cell" FBgn0025726 unc-13 unc-13 http://flybase.net/reports/FBgn0025726.html FBgn0013637 protein_coding_gene "0019992=diacylglycerol binding, 0005516=calmodulin binding" "0016082=synaptic vesicle priming, 0007268=synaptic transmission, 0007269=neurotransmitter secretion, 0016079=synaptic vesicle exocytosis, 0035556=intracellular signal transduction" "0045211=postsynaptic membrane, 0043195=terminal bouton, 0008021=synaptic vesicle" "Munc-13/UNC-13, l(4)ry16, UNC-13-B, lethal (4) ry16, Munc-13, Dunc-13, DUNC-13, dunc-13, Unc-13, drunc13, unc, dUnc-13, unnamed, UNC-13, dUNC-13, CG2999, Dunc13" "IPR014772=Mammalian uncoordinated homology 13, domain 2, IPR014770=Munc13 homology 1, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR027080=Uncoordinated protein 13 (Unc-13), IPR010439=Calcium-dependent secretion activator, IPR019558=Mammalian uncoordinated homology 13, subgroup, domain 2, IPR000008=C2 domain" CG2999 16-Dec-15 2015_12 WBGene00006752(unc-13) "ENSXETG00000006341(UNC13C),ENSXETG00000013597(UNC13A)" "ENSG00000130477(UNC13A),ENSG00000198722(UNC13B)" " pupal stage , adult stage " adult head

"viable,fertile,paralytic,recessive,neurophysiology defective,lethal,feeding behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" synaptic vesicle FBgn0022962 spongecake spongecake http://flybase.net/reports/FBgn0022962.html gene 16-Dec-15 2015_12 "short lived,recessive,heat sensitive,lethal" "medulla,lamina,lobula,optic lobe & neuropil,optic lobe" FBgn0037634 hng2 hinge2 http://flybase.net/reports/FBgn0037634.html protein_coding_gene 0003677=DNA binding "Hinge2, CG8359" "IPR006578=MADF domain, IPR004210=BESS motif" CG8359 16-Dec-15 2015_12 "flightless,viable,fertile" wing hinge DRSC16412 K 1.155081088 0.227484148 0.091084622 -0.471310292 -0.664829853 -1.727014753 FBgn0024554 l(3)L4111 lethal (3) L4111 http://flybase.net/reports/FBgn0024554.html gene Mgn95009 16-Dec-15 2015_12 "lethal,recessive" FBgn0037036 Sems Seminase http://flybase.net/reports/FBgn0037036.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" "0032504=multicellular organism reproduction, 0045434=negative regulation of female receptivity, post-mating, 0031638=zymogen activation, 0046693=sperm storage, 0006508=proteolysis" 0005615=extracellular space "SP168, sems, CG10586, seminase" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG10586 16-Dec-15 2015_12 "viable,mating behavior defective" FBgn0265816 CR44605 http://flybase.net/reports/FBgn0265816.html non_protein_coding_gene lincRNA.178 CR44605 16-Dec-15 2015_12 FBgn0062413 Ctr1A Copper transporter 1A http://flybase.net/reports/FBgn0062413.html "FBgn0029886, FBgn0062940" protein_coding_gene "0015088=copper uptake transmembrane transporter activity, 0005375=copper ion transmembrane transporter activity" "0006825=copper ion transport, 0006878=cellular copper ion homeostasis, 0015679=plasma membrane copper ion transport, 0002027=regulation of heart rate, 0035434=copper ion transmembrane transport" "0005886=plasma membrane, 0016021=integral component of membrane" "DmCtr1A, BcDNA:RH42635, ctr1A, CG3977" IPR007274=Ctr copper transporter CG3977 16-Dec-15 2015_12 ENSDARG00000013961(slc31a1) YHR175W(CTR2) WBGene00017852(F27C1.2) ENSXETG00000026232(slc31a1) ENSMUSG00000066150(Slc31a1) ENSG00000136868(SLC31A1) "visible,recessive,maternal effect,lethal,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,body color defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "mouth hooks,spiracle primordium,maternal effect,abdomen,mesothoracic bristle,embryonic/larval heart,adult cuticle,trichogen cell,mesothoracic tergum,eye,ommatidium" DRSC18336 I -0.378167999 -2.130772434 -0.884756047 0.201944141 1.370484247 1.041430506 FBgn0030092 fh frataxin homolog http://flybase.net/reports/FBgn0030092.html FBgn0062513 protein_coding_gene "0004322=ferroxidase activity, 0034986=iron chaperone activity, 0008199=ferric iron binding" "0019896=axon transport of mitochondrion, 0045998=positive regulation of ecdysteroid biosynthetic process, 0055114=oxidation-reduction process, 0016226=iron-sulfur cluster assembly, 0051881=regulation of mitochondrial membrane potential, 0035073=pupariation, 0045823=positive regulation of heart contraction, 0006879=cellular iron ion homeostasis, 0042542=response to hydrogen peroxide" 0005739=mitochondrion "Frataxin, dfh, BcDNA:AT09528, CG8971, X25, DFH, frataxin-like, frataxin, frataxin homologue, Dfh" "IPR002908=Frataxin/CyaY, IPR017789=Frataxin, IPR020895=Frataxin conserved site" CG8971 16-Dec-15 2015_12 ENSDARG00000069502(LOC100329824) YDL120W(YFH1) WBGene00001486(frh-1) ENSXETG00000000575(FXN) ENSMUSG00000059363(Fxn) ENSG00000165060(FXN) "developmental rate defective,partially,short lived,chemical sensitive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,locomotor rhythm defective,gravitaxis defective,conditional,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,some die during third instar larval stage,locomotor behavior defective,chemical resistant,stress response defective,long lived" "ventral nerve cord | third instar larval stage,motor neuron | third instar larval stage,mitochondrion | third instar larval stageD42,adult heart,RU486 conditional,A1-7 dorsal acute muscle 3,A1-7 dorsal oblique muscle 3,A1-7 dorsal oblique muscle 4,motor neuron,sensory neuron,embryonic/larval pericardial cell" FBgn0060526 l(3)S101801b lethal (3) S101801b http://flybase.net/reports/FBgn0060526.html gene 1018/01 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0005268 l(3)SG88 lethal (3) SG88 http://flybase.net/reports/FBgn0005268.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0043478 l(3)66EFh lethal (3) 66EFh http://flybase.net/reports/FBgn0043478.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0030104 CG15368 http://flybase.net/reports/FBgn0030104.html protein_coding_gene 0008270=zinc ion binding "IPR000058=Zinc finger, AN1-type" CG15368 16-Dec-15 2015_12 "ENSDARG00000033811,ENSDARG00000002271(zfand5b),ENSDARG00000018898(zfand5a),ENSDARG00000027832(zgc:77486)" "ENSXETG00000025293(Q6P840_XENTR),ENSXETG00000014368(za20d2)" "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0003700 thm thin macros http://flybase.net/reports/FBgn0003700.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" macrochaeta FBgn0005017 dipp-8 defective in phototaxis plasticity 8 http://flybase.net/reports/FBgn0005017.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective,phototaxis defective" FBgn0030522 CG11103 http://flybase.net/reports/FBgn0030522.html FBgn0063126 protein_coding_gene BcDNA:LP03404 IPR007829=TM2 domain CG11103 16-Dec-15 2015_12 ENSDARG00000035515(zgc:92201) WBGene00015353(C02F5.13) ENSXETG00000015155(tm2d2) ENSMUSG00000031556(Tm2d2) ENSG00000169490(TM2D2) "viable,visible" trichogen cell FBgn0259480 EP-54 http://flybase.net/reports/FBgn0259480.html gene 16-Dec-15 2015_12 visible "wing,wing vein,chaeta" FBgn0040385 CG12496 http://flybase.net/reports/FBgn0040385.html FBgn0029617 protein_coding_gene EG:BACH7M4.4 CG12496 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,tormogen cell,mesothoracic tergum" FBgn0260063 2L3311 http://flybase.net/reports/FBgn0260063.html gene 16-Dec-15 2015_12 "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0016954 tilK touch insensitive larva K http://flybase.net/reports/FBgn0016954.html gene line 147 16-Dec-15 2015_12 "touch sensitivity defective,recessive,visible,somatic clone,behavior defective" "macrochaeta,somatic clone,leg" FBgn0040725 CG13946 http://flybase.net/reports/FBgn0040725.html protein_coding_gene CG13946 16-Dec-15 2015_12 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0259431 C875 http://flybase.net/reports/FBgn0259431.html gene 16-Dec-15 2015_12 visible wing FBgn0016707 Reg-12 Rhythmically expressed gene 12 http://flybase.net/reports/FBgn0016707.html gene "Dreg-12, Drosophila Rhythmically expressed gene 12" 16-Dec-15 2015_12 " embryonic stage | late , adult stage " head

FBgn0259338 C356 http://flybase.net/reports/FBgn0259338.html gene 16-Dec-15 2015_12 visible wing vein FBgn0038350 AOX4 Aldehyde oxidase 4 http://flybase.net/reports/FBgn0038350.html protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding, 0050660=flavin adenine dinucleotide binding, 0004031=aldehyde oxidase activity, 0016614=oxidoreductase activity, acting on CH-OH group of donors, 0009055=electron carrier activity, 0005506=iron ion binding" "0006081=cellular aldehyde metabolic process, 0055114=oxidation-reduction process" "DmAO4, CG18516" "IPR012675=Beta-grasp domain, IPR000674=Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR016166=FAD-binding, type 2, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR002888=[2Fe-2S]-binding, IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR002346=Molybdopterin dehydrogenase, FAD-binding, IPR016208=Aldehyde oxidase/xanthine dehydrogenase, IPR008274=Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR005107=CO dehydrogenase flavoprotein, C-terminal, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain" CG18516 16-Dec-15 2015_12 FBgn0000961 fs(2)E8 female sterile (2) E8 http://flybase.net/reports/FBgn0000961.html gene fs2.8 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0002223 l(3)68Ac lethal (3) 68Ac http://flybase.net/reports/FBgn0002223.html gene "l(3)C178, H, l(3)H, Complementation group H, l(3)68Ac'" 16-Dec-15 2015_12 "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage,visible" "wing,leg" FBgn0002721 mesB messy B http://flybase.net/reports/FBgn0002721.html gene "mes-B, messy, 0303/02, l(3)mes-4B" 16-Dec-15 2015_12 "lethal,visible,partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,trident,adult thorax & macrochaeta,adult abdomen,thorax,dorsal" FBgn0000878 fs(1)M76 female sterile (1) M76 http://flybase.net/reports/FBgn0000878.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0026317 Tsc1 Tsc1 http://flybase.net/reports/FBgn0026317.html protein_coding_gene 0019900=kinase binding "0035883=enteroendocrine cell differentiation, 0007584=response to nutrient, 0048477=oogenesis, 2000377=regulation of reactive oxygen species metabolic process, 0008340=determination of adult lifespan, 0036335=intestinal stem cell homeostasis, 0048640=negative regulation of developmental growth, 0042127=regulation of cell proliferation, 0001558=regulation of cell growth, 0030308=negative regulation of cell growth, 0008286=insulin receptor signaling pathway, 0046620=regulation of organ growth, 0048505=regulation of timing of cell differentiation, 0038202=TORC1 signaling, 1902350=cellular response to chloroquine, 0042325=regulation of phosphorylation, 0071456=cellular response to hypoxia, 0006629=lipid metabolic process, 0051726=regulation of cell cycle, 0046621=negative regulation of organ growth, 0010508=positive regulation of autophagy, 0007165=signal transduction, 0043547=positive regulation of GTPase activity, 0060439=trachea morphogenesis, 0035069=larval midgut histolysis, 0008285=negative regulation of cell proliferation, 0045792=negative regulation of cell size, 0046627=negative regulation of insulin receptor signaling pathway, 2000331=regulation of terminal button organization" "0005737=cytoplasm, 0033596=TSC1-TSC2 complex" "unnamed, dTSC1, Tuberous sclerosis complex 1, TSC, CG6147, dtsc1, Tuberous Sclerosis 1, hamartin, jolly green giant, dTsc1, dTSC, tuberous sclerosis 1, rocky, TTuberous Sclerosis Complex 1, TSC1, Tuberous Sclerosis Complex 1, dTSC-1, tuberous sclerosis complex 1, tsc1" IPR007483=Hamartin CG6147 16-Dec-15 2015_12 "ENSDARG00000057918,ENSDARG00000026048(tsc1a)" ENSXETG00000006262() ENSMUSG00000026812(Tsc1) ENSG00000165699(TSC1) "increased cell death,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal,conditional,increased cell size,decreased cell growth,decreased cell death,visible,recessive,developmental rate defective,size defective,wild-type,cell autonomous,increased cell number,mitotic cell cycle defective,planar polarity defective,calorie restriction conditional,hyperplasia,long lived,viable" "eye disc,somatic clone,morphogenetic furrow,eye,ommatidium,intestinal stem cell,enteroendocrine cell,head capsule,cell autonomous,interommatidial bristle,rhabdomere | cell autonomous | somatic clone,eye photoreceptor cell,supernumerary,imaginal disc,wing margin bristle,rhabdomere,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,cone cell,ommatidial precursor cluster,melanotic mass,wing disc,eye disc & S phase | somatic clone,eye disc & mitotic cell cycle | somatic clone,adult head,eye-antennal disc,eye disc & S phase | ectopic | somatic clone,eye disc & mitotic cell cycle | ectopic | somatic clone,wing,fat body,chaeta,mesothoracic tergum,macrochaeta,ectopic,terminal tracheal cell,embryonic/larval tracheal system" FBgn0004875 enc encore http://flybase.net/reports/FBgn0004875.html "FBgn0014170, FBgn0035466" protein_coding_gene 0003676=nucleic acid binding "0007282=cystoblast division, 0007309=oocyte axis specification, 0007310=oocyte dorsal/ventral axis specification, 0048477=oogenesis, 0048134=germ-line cyst formation, 0030717=karyosome formation, 0007294=germarium-derived oocyte fate determination, 0007317=regulation of pole plasm oskar mRNA localization, 0007293=germarium-derived egg chamber formation, 0007067=mitotic nuclear division" 0005737=cytoplasm "fs(3)63F-64A, CG10847, unnamed, Encore, BB129, Enc" "IPR001374=R3H domain, IPR024771=SUZ domain" CG10847 16-Dec-15 2015_12 "ENSDARG00000063141,ENSDARG00000038912" "ENSMUSG00000032503(Arpp21),ENSMUSG00000056211(R3hdm1),ENSMUSG00000025404(R3hdm2)" "ENSG00000048991(R3HDM1),ENSG00000179912(R3HDM2),ENSG00000172995(ARPP21)" " spermatogenesis && adult stage , adult stage | female && oogenesis stage , adult stage && oogenesis stage | mid , adult stage | female && oogenesis stage | , adult stage && oogenesis stage | stage S9 " " testis | restricted

, germarium region 1 && female germline stem cell

, oocyte | posterior

, germarium region 1 && cystocyte

, oocyte | anterior

" "female sterile,mitotic cell cycle defective,recessive,heat sensitive,cold sensitive,viable,lethal,maternal effect" "karyosome,dorsal appendage,follicle cell,egg chamber,chorion,ovary,nurse cell,oocyte nucleus,maternal effect,embryonic/larval posterior spiracle,filzkorper,anal pad,embryonic/first instar larval cuticle" FBgn0010247 Parp Poly-(ADP-ribose) polymerase http://flybase.net/reports/FBgn0010247.html "FBgn0039975, FBgn0039998, FBgn0046268, FBgn0058411, FBan0040411" protein_coding_gene "0008270=zinc ion binding, 0003950=NAD+ ADP-ribosyltransferase activity, 0042393=histone binding, 0051287=NAD binding, 0003677=DNA binding" "0030576=Cajal body organization, 0007000=nucleolus organization, 0051457=maintenance of protein location in nucleus, 0006355=regulation of transcription, DNA-templated, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0051276=chromosome organization, 0009303=rRNA transcription, 0043484=regulation of RNA splicing, 0048812=neuron projection morphogenesis, 0035080=heat shock-mediated polytene chromosome puffing, 0045087=innate immune response, 0007552=metamorphosis, 0035079=polytene chromosome puffing, 0006471=protein ADP-ribosylation, 0006963=positive regulation of antibacterial peptide biosynthetic process" "0005703=polytene chromosome puff, 0005719=nuclear euchromatin, 0005700=polytene chromosome, 0005730=nucleolus, 0005694=chromosome, 0035363=histone locus body, 0005634=nucleus, 0015030=Cajal body" "dPARP, Poly(ADP ribose) polymerase 1, BEST:LD21673, poly(ADP-ribose) polymerase, CG17696, LD21673.3prime, poly ADP ribose polymerase, CG17685, Poly (ADP-ribose) polymerase, dmparp, Poly(ADP)-Ribose Polymerase, parp, PARP1, CG17718, D.PARP, PARP, Poly(ADP-ribose) polymerase, (Poly (ADP-ribose) polymeras, PARP-1, poly-(ADP-ribose) polymerase, Parp1, Poly(ADP-ribose) Polymerase 1, Dm.pARTa, Poly(ADP-)Ribose Polymerase, CG40411" "IPR001510=Zinc finger, PARP-type, IPR001357=BRCT domain, IPR012317=Poly(ADP-ribose) polymerase, catalytic domain, IPR008893=WGR domain, IPR008288=NAD+ ADP-ribosyltransferase, IPR004102=Poly(ADP-ribose) polymerase, regulatory domain, IPR012982=PADR1" CG40411 16-Dec-15 2015_12 ENSDARG00000019529(parp1) WBGene00004049(pme-1) ENSXETG00000022610(PARP1) ENSMUSG00000026496(Parp1) ENSG00000143799(PARP1) " embryonic stage | stage 14,15 , adult stage && oogenesis stage | stage S10 , embryonic stage | stage 16 , embryonic stage && pupal stage && adult stage , adult stage && oogenesis stage | stage S11,12 , embryonic stage " " embryonic central nervous system | vicinity of

, nurse cell

, anal plate

, oocyte

,

ubiquitous " "viable,immune response defective,heat stress response defective,aging defective,lethal - all die before end of larval stage,recessive,some die during larval stage,non-enhancer of variegation,non-suppressor of variegation,planar polarity defective,heat sensitive,visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "polytene chromosome puff,nucleolus,cephalopharyngeal skeleton,nucleus,polytene chromosome chromocenter,wing hair,heat sensitive,eye,adult abdomen,mesothoracic tergum,actin filament & embryonic epidermis | conditional ts,ommatidium,pigment cell,cone cell,ommatidial precursor cluster,photoreceptor cell R3,photoreceptor cell R4,eye disc,actin filament & retina,adult abdomen & cuticlearm.PS" FBgn0002926 ndl nudel http://flybase.net/reports/FBgn0002926.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity, 0008233=peptidase activity" "0007313=maternal specification of dorsal/ventral axis, oocyte, soma encoded, 0007306=eggshell chorion assembly, 0016485=protein processing, 0007310=oocyte dorsal/ventral axis specification, 0007343=egg activation, 0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway, 0006508=proteolysis" 0005576=extracellular region "Nudel, CG10129, SP89, Ndl, mel(3)5, nud, mat(3)2" "IPR015420=Peptidase S1A, nudel, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat" CG10129 16-Dec-15 2015_12 adult stage && oogenesis stage | stage S7-10 oocyte | anterior

"lethal,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,viable" "egg,maternal effect,chorion | maternal effect,blastoderm embryo,vitelline membrane,embryonic/first instar larval cuticle,embryonic epidermis,embryo,ventral" FBgn0002299 l(3)80Fj lethal (3) 80Fj http://flybase.net/reports/FBgn0002299.html gene "80Fj, lethal 1, l1, l(3)Lh1" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004636 Rap1 Rap1 GTPase http://flybase.net/reports/FBgn0004636.html "FBgn0003190, FBgn0003207, FBgn0045818" protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding, 0019003=GDP binding" "0032486=Rap protein signal transduction, 0046328=regulation of JNK cascade, 0007155=cell adhesion, 0022409=positive regulation of cell-cell adhesion, 0008360=regulation of cell shape, 0030718=germ-line stem cell maintenance, 0030713=ovarian follicle cell stalk formation, 0006930=substrate-dependent cell migration, cell extension, 0007391=dorsal closure, 0034333=adherens junction assembly, 0035099=hemocyte migration, 0016476=regulation of embryonic cell shape, 0042067=establishment of ommatidial planar polarity, 0001752=compound eye photoreceptor fate commitment" "0005886=plasma membrane, 0005811=lipid particle, 0031252=cell leading edge" "CG1956, EC3-7, ras 3, ras3, RasIII, RAP1, roughened, Rap1, Rap, l(3)62Bf, DRap1, E(faf), Roughened, DRap, l(3)R, Ras3, C-ras3, rap1, P08645, Rap1 GTPase, Dras62B, Enhancer of faf, BEST:GH18528, D-Rap1, Dras3, R, FCG-C" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR020849=Small GTPase superfamily, Ras type" CG1956 16-Dec-15 2015_12 "ENSDARG00000012553(rap1a),ENSDARG00000058275,ENSDARG00000008867(rap1b)" WBGene00004307(rap-1) ENSXETG00000013562(rap1b) "ENSMUSG00000068798(Rap1a),ENSMUSG00000052681(Rap1b)" "ENSG00000116473(RAP1A),ENSG00000127314(RAP1B),ENSG00000176276" " adult stage && oogenesis stage , larval stage | third instar , adult stage , embryonic stage " " oocyte

, genital disc

, thoracico-abdominal ganglion

, larval brain | restricted

, dorsal mesothoracic disc

, eye-antennal disc

, adult brain | resticted

" "viable,visible,recessive,lethal,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,wild-type,lethal - all die before end of larval stage,some die during larval stage,dominant,lethal - all die before end of pupal stage,some die during pupal stage,cell shape defective" "eye photoreceptor cell,eye,photoreceptor cell R7,ommatidium,rhabdomere | supernumerary,adherens junction | somatic clone,wing,somatic clone,macrophage,follicle cell,gastrula embryo,germline clone,maternal effect,ventral furrow,ventral nerve cord,embryonic head,mesoderm,embryonic/larval dorsal vessel,pole cell,dorsal closure embryo,embryonic/first instar larval cuticle,anterior,ventral,ovary,egg chamber,germarium,interfollicle cell,nurse cell,secondary pigment cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R8,retinal pigment cell,photoreceptor cell,cone cell,supernumerary,border follicle cell,glial cell,hemocyte" DRSC08686 E -0.948643252 -0.987534674 -2.516345909 -1.350297313 0.121309967 0.45782299 FBgn0028992 sds22 sds22 http://flybase.net/reports/FBgn0028992.html FBgn0038503 protein_coding_gene 0008599=protein phosphatase type 1 regulator activity "0016334=establishment or maintenance of polarity of follicular epithelium, 0008285=negative regulation of cell proliferation, 0016336=establishment or maintenance of polarity of larval imaginal disc epithelium" 0000164=protein phosphatase type 1 complex "CG5851, CT18355, Sds22" "IPR001611=Leucine-rich repeat, IPR025875=Leucine rich repeat 4" CG5851 16-Dec-15 2015_12 ENSDARG00000009740 YKL193C(SDS22) WBGene00015516(C06A8.6) ENSXETG00000012163(ppp1r7) ENSMUSG00000026275(Ppp1r7) ENSG00000115685(PPP1R7) "lethal,visible,somatic clone,partially lethal - majority die,some die during pupal stage" "wing disc,somatic clone,follicle cell,nurse cell,eye photoreceptor cell,eye,eye disc,trichogen cell,mesothoracic tergum" FBgn0010235 Klc Kinesin light chain http://flybase.net/reports/FBgn0010235.html protein_coding_gene 0003777=microtubule motor activity "0051726=regulation of cell cycle, 0007018=microtubule-based movement, 0007017=microtubule-based process, 0046843=dorsal appendage formation" "0005871=kinesin complex, 0005875=microtubule associated complex" "kinesin-1, kinesin light chain, CG5433, kinesin light chain subunit of kinesin-1, Kinesin-1, Kinesin 1 light chain, DKLC, kinesin, klc, Kinesin Light Chain, kinesin I, kinesin-1 light chain, KLC" "IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR002151=Kinesin light chain, IPR013026=Tetratricopeptide repeat-containing domain, IPR015792=Kinesin light chain repeat" CG5433 16-Dec-15 2015_12 "ENSDARG00000009796(zgc:66299),ENSDARG00000020635" WBGene00002215(klc-2) ENSXETG00000023054(kns2) "ENSMUSG00000021288(Klc1),ENSMUSG00000003546(Klc4),ENSMUSG00000024862(Klc2)" "ENSG00000126214(KLC1),ENSG00000137171(KLC4),ENSG00000174996(KLC2)" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,paralytic,lethal - all die before end of larval stage,some die during larval stage,viable,visible" "dorsal appendage,germline clone,maternal effect,eye,somatic clone,embryonic/larval nervous system,trichogen cell" FBgn0004957 por porcupine http://flybase.net/reports/FBgn0004957.html FBgn0003126 protein_coding_gene "0016746=transferase activity, transferring acyl groups" "0030111=regulation of Wnt signaling pathway, 0006497=protein lipidation, 0009306=protein secretion" "0005783=endoplasmic reticulum, 0005886=plasma membrane" "15175, Porc, l(1)17Ac, poc, CG6205, Porcupine, porc, dmPorc" "IPR004299=Membrane bound O-acyl transferase, MBOAT" CG6205 16-Dec-15 2015_12 "ENSDARG00000028819(LOC100148644),ENSDARG00000052455(zgc:55392),ENSDARG00000052558(LOC100006275)" WBGene00003394(mom-1) ENSXETG00000007920(porcn) ENSMUSG00000031169(Porcn) ENSG00000102312(PORCN) " embryonic stage | early , embryonic stage -- adult stage " "lethal,recessive,rescuable maternal effect,germline clone,segment polarity phenotype,lethal - all die before end of larval stage,some die during larval stage,wild-type,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "bouton,interommatidial bristle,embryonic/larval tracheal system,germline clone,embryonic/larval dorsal trunk,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,presumptive embryonic/larval central nervous system,denticle belt,embryonic head,embryonic/first instar larval cuticle,wing,wing & macrochaeta,antenna,leg,distal,unguis,supernumerary,sex comb,tergite,embryo,chaeta,trichogen cell" FBgn0005411 U2af50 U2 small nuclear riboprotein auxiliary factor 50 http://flybase.net/reports/FBgn0005411.html protein_coding_gene "0008187=poly-pyrimidine tract binding, 0003723=RNA binding, 0003729=mRNA binding, 0046982=protein heterodimerization activity, 0000166=nucleotide binding, 0005515=protein binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0008380=RNA splicing, 0000245=spliceosomal complex assembly, 0000398=mRNA splicing, via spliceosome, 0051168=nuclear export, 0046833=positive regulation of RNA export from nucleus, 0022008=neurogenesis, 0007052=mitotic spindle organization" "0005634=nucleus, 0005686=U2 snRNP, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005654=nucleoplasm" "dU2AF50, dUTAf[50], U2AF50, 9-21, U2AF, DU2AF50, l(1)14Ca, DmU2AF[50], U2AF 50, U2AF-50, l(1)9-21, CG9998, U2af, dU2AF[50], l(1)14Cc" "IPR000504=RNA recognition motif domain, IPR006529=U2 snRNP auxilliary factor, large subunit, splicing factor, IPR012677=Nucleotide-binding alpha-beta plait domain" CG9998 16-Dec-15 2015_12 "ENSDARG00000012505(u2af2a),ENSDARG00000011740(u2af2b)" WBGene00006697(uaf-1) ENSXETG00000019128(u2af2) ENSMUSG00000030435 ENSG00000063244(U2AF2) embryonic stage -- adult stage "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,visible" "embryonic/larval neuroblast,ganglion mother cell,wing" DRSC22867 IE -2.023704675 -2.179365099 -4.364589509 -4.207026992 0.605461637 0.85483062 FBgn0065521 l(2)SH1128 lethal (2) SH1128 http://flybase.net/reports/FBgn0065521.html gene l(2)SH2 1128 16-Dec-15 2015_12 "lethal,recessive" FBgn0028948 CG15253 http://flybase.net/reports/FBgn0028948.html protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" 0006508=proteolysis "BG:BACR44L22.3, BACR44L22.3" "IPR024079=Metallopeptidase, catalytic domain, IPR006026=Peptidase, metallopeptidase, IPR001506=Peptidase M12A, astacin" CG15253 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC01871 K -0.211719476 0.557519894 -0.341536916 -0.160900012 -1.740904126 0.10496823 FBgn0027296 temp tempura http://flybase.net/reports/FBgn0027296.html FBgn0029609 protein_coding_gene 0004663=Rab geranylgeranyltransferase activity "0007423=sensory organ development, 0018344=protein geranylgeranylation" "0005968=Rab-protein geranylgeranyltransferase complex, 0005737=cytoplasm" "CG3073, l(1)G0144, lethal (1) G0144" "IPR002088=Protein prenyltransferase, alpha subunit" CG3073 16-Dec-15 2015_12 "ENSDARG00000067695(si:ch211-117c19.3),ENSDARG00000067693" ENSMUSG00000074925(Ptar1) "lethal,some die during second instar larval stage,some die during third instar larval stage,visible,somatic clone,lethal - all die during third instar larval stage,recessive,female,viable" "mesothoracic tergum,somatic clone,chaeta,external sensory organ precursor cell I,tormogen cell,eo neuron,supernumerary" FBgn0040126 l(2)23CDb lethal (2) 23CDb http://flybase.net/reports/FBgn0040126.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0036925 schuy schumacher-levy http://flybase.net/reports/FBgn0036925.html protein_coding_gene CG17736 CG17736 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000444 dg-a degenerated spermatheca http://flybase.net/reports/FBgn0000444.html gene 16-Dec-15 2015_12 "viable,good,fertile" spermathecal duct FBgn0027835 Dp1 Dodeca-satellite-binding protein 1 http://flybase.net/reports/FBgn0027835.html "FBgn0027520, FBgn0027530, FBgn0046433, FBgn0061926" protein_coding_gene "0003696=satellite DNA binding, 0003697=single-stranded DNA binding, 0003730=mRNA 3'-UTR binding" "0030261=chromosome condensation, 0045727=positive regulation of translation, 0007059=chromosome segregation, 0031507=heterochromatin assembly" "0030529=ribonucleoprotein complex, 0005811=lipid particle, 0005701=polytene chromosome chromocenter, 0005634=nucleus, 0000792=heterochromatin" "Drosophila dodeca-satellite-binding protein 1, anon-WO0118547.516, anon-WO0172774.168, BcDNA:LD21677, DDP1, CG5170, ddp1, Dodeca satellite binding protein 1, dodeca-satellite protein 1, dodeca-satellite-binding protein 1, Vigilin, BcDNA:LD21383" "IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG5170 16-Dec-15 2015_12 "ENSDARG00000009830(hdlbp),ENSDARG00000061864" YJL080C(SCP160) WBGene00007463(C08H9.2) ENSXETG00000012164(BC076949.1) ENSMUSG00000034088(Hdlbp) ENSG00000115677(HDLBP) "lethal,recessive,partially,suppressor of variegation,dominant,female sterile,non-rescuable maternal effect,viable,non-suppressor of variegation,partially lethal - majority die" "ovary,ovariole,egg chamber,egg,maternal effect,mitotic anaphase | embryonic stage | maternal effect,mitotic telophase | embryonic stage | maternal effect,nucleus | embryonic stage | maternal effect" FBgn0013718 nuf nuclear fallout http://flybase.net/reports/FBgn0013718.html "FBgn0013768, FBgn0015626, FBgn0024703, FBgn0044464, FBgn0052140, FBgn0053991, FBtr0075731, FBpp0075474, FBtr0075732, FBpp0075475, FBtr0075733, FBpp0075476, FBtr0075734, FBtr0075738, FBpp0075480, FBtr0075739, FBpp0075481, FBpp0089174" protein_coding_gene 0008017=microtubule binding "0016360=sensory organ precursor cell fate determination, 0007017=microtubule-based process, 0031532=actin cytoskeleton reorganization, 0000915=actomyosin contractile ring assembly, 0007476=imaginal disc-derived wing morphogenesis, 0048190=wing disc dorsal/ventral pattern formation" "0005875=microtubule associated complex, 0005815=microtubule organizing center, 0048471=perinuclear region of cytoplasm, 0045179=apical cortex, 0005813=centrosome" "Nuclear-fallout, Cy3-23, D2, EP3077, CIP-D2, FIP3, Nuclear fallout, Nuf2p, Nuf1, anon-D2, NUF, Nuclear Fallout, CG33991, Corkscrew Interacting Protein-D2, nuclear-fallout, Nuf, unnamed, CG32140, CG7867" IPR019018=Rab-binding domain FIP-RBD CG33991 16-Dec-15 2015_12 "ENSDARG00000053855(rab11fip4a),ENSDARG00000067680,ENSDARG00000070319(rab11fip4b),ENSDARG00000016490(si:ch211-153c20.4)" WBGene00018869(F55C12.1) ENSXETG00000010330(RAB11FIP3) "ENSMUSG00000017639(Rab11fip4),ENSMUSG00000037098(Rab11fip3)" "ENSG00000131242(RAB11FIP4),ENSG00000090565(RAB11FIP3)" embryonic stage | 0-3 hr " embryonic stage | cellular blastoderm , embryonic stage | 0-3 hr , embryonic stage | syncytial blastoderm " "visible,viable,fertile,neuroanatomy defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,recessive,wild-type,partially lethal - majority die,some die during pupal stage" "scutellar bristle,ectopic,trichogen cell,socket,supernumerary,macrochaeta,intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse,nucleus | embryonic stage,actin cytoskeleton | embryonic stage,cycle 11 embryo,maternal effect,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo,mitotic telophase | maternal effect,cleavage furrow,wing,eye" FBgn0040147 l(1)G0478 lethal (1) G0478 http://flybase.net/reports/FBgn0040147.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0002235 l(3)68Bb lethal (3) 68Bb http://flybase.net/reports/FBgn0002235.html FBgn0002229 gene "B, l(3)C46, l(3)B, Complementation group B" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,female sterile" wing FBgn0082591 inferno inferno http://flybase.net/reports/FBgn0082591.html gene 0007349=cellularization 16-Dec-15 2015_12 "centrosome | embryonic stage | heat sensitive,microtubule | embryonic stage | heat sensitive" FBgn0001345 l(1)1Dc lethal (1) 1Dc http://flybase.net/reports/FBgn0001345.html gene JC45 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002222 l(3)68Ab lethal (3) 68Ab http://flybase.net/reports/FBgn0002222.html gene l(3)C493 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,recessive,partially lethal - majority die,visible,lethal" eye FBgn0039555 mRpS22 mitochondrial ribosomal protein S22 http://flybase.net/reports/FBgn0039555.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "AAF56757, MrpS22, MRP-S22, Mitochondrial ribosomal protein S22, CG12261" "IPR019374=Ribosomal protein S22, mitochondrial" CG12261 16-Dec-15 2015_12 ENSDARG00000018073(zgc:165596) WBGene00007564(C14A4.14) ENSXETG00000008251(MRPS22) ENSMUSG00000032459(Mrps22) ENSG00000175110(MRPS22) "viable,visible" trichogen cell FBgn0029117 Surf1 Surfeit 1 http://flybase.net/reports/FBgn0029117.html "FBgn0035723, FBgn0063225" protein_coding_gene 0015232=heme transporter activity "0042331=phototaxis, 0033617=mitochondrial respiratory chain complex IV assembly, 0022008=neurogenesis, 0009060=aerobic respiration, 0002168=instar larval development, 0007632=visual behavior, 0008535=respiratory chain complex IV assembly" 0005743=mitochondrial inner membrane "SUR1, CG9943, BcDNA:GH23574, Surfeit locus protein 1" IPR002994=Surfeit locus 1/Shy1 CG9943 16-Dec-15 2015_12 ENSDARG00000003592(surf1) YGR112W(SHY1) WBGene00004787(sft-1) ENSMUSG00000015790(Surf1) ENSG00000148290(SURF1) "lethal,partially,developmental rate defective,small body,phototaxis defective,locomotor behavior defective,long lived,neurophysiology defective,optomotor response defective,RU486 conditional,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval optic lobe,postsynaptic membrane,mitochondrion,ganglion mother cell,mesothoracic tergum" DRSC11295 I 0.125497666 -1.879791391 -0.409020076 -0.466199394 0.26700563 -0.145583445 FBgn0034697 GM130 Golgi matrix protein 130 kD ortholog http://flybase.net/reports/FBgn0034697.html protein_coding_gene 0017137=Rab GTPase binding "0050775=positive regulation of dendrite morphogenesis, 0048193=Golgi vesicle transport, 0007030=Golgi organization" "0005795=Golgi stack, 0000137=Golgi cis cisterna, 0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "GM-130, GM130, dgm130, dGM130, CG11061" "IPR002395=HMW kininogen, IPR024858=Golgin subfamily A" CG11061 16-Dec-15 2015_12 ENSDARG00000063197(golga2) WBGene00018017(F33G12.5) "ENSG00000167110(GOLGA2),ENSG00000103832" "neuroanatomy defective,viable,fertile,partially lethal - majority die,some die during pupal stage" "Golgi apparatus,dendritic arborizing neuron,dendrite,microtubule,dendritic branch point,class III dendritic arborizing neuron,Golgi apparatus19-12,dendritic arborizing neuron | larval stage,dendrite19-12,microtubule19-12,dendritic branch point19-12,class III dendritic arborizing neuron | larval stage" FBgn0062612 Mod(var)1309 Mod(var)1309 http://flybase.net/reports/FBgn0062612.html gene 0006342=chromatin silencing 1309 16-Dec-15 2015_12 "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0062584 Mod(var)177 Mod(var)177 http://flybase.net/reports/FBgn0062584.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 177 16-Dec-15 2015_12 "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,viable" FBgn0016061 side sidestep http://flybase.net/reports/FBgn0016061.html "FBgn0039515, FBgn0039516, FBgn0039517, FBgn0040611, FBgn0040612, FBgn0051062, FBgn0063636" protein_coding_gene 0008045=motor neuron axon guidance "CG12510, CG31062, Sidestep, Side, CG13974, CT33527, CG13975, doe, downstream of eyeless, CG13973, Doe, CT33528, CG13979" "IPR007110=Immunoglobulin-like domain, IPR013162=CD80-like, immunoglobulin C2-set, IPR013106=Immunoglobulin V-set domain, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG31062 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" "neuroanatomy defective,oxidative stress response defective,viable" "intersegmental nerve,segmental nerve,abdominal intersegmental nerve,abdominal segmental nerve,larval neuromuscular junction & abdominal dorsal acute muscle 1,larval neuromuscular junction & abdominal dorsal oblique muscle 1,larval neuromuscular junction & abdominal dorsal acute muscle 2,larval neuromuscular junction & abdominal dorsal oblique muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 1,larval neuromuscular junction & abdominal lateral transverse muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 3,larval neuromuscular junction & abdominal lateral transverse muscle 4,larval neuromuscular junction & abdominal ventral longitudinal muscle 1,larval neuromuscular junction & abdominal ventral longitudinal muscle 2,larval neuromuscular junction & abdominal ventral longitudinal muscle 3,larval neuromuscular junction & abdominal ventral longitudinal muscle 4,larval neuromuscular junction & abdominal ventral acute muscle 1,larval neuromuscular junction & abdominal ventral acute muscle 2,larval neuromuscular junction & abdominal ventral acute muscle 3,larval neuromuscular junction & abdominal ventral oblique muscle 4,larval neuromuscular junction & abdominal ventral oblique muscle 5,larval neuromuscular junction & abdominal ventral oblique muscle 6,growth cone & intersegmental nerve,A1-7 dorsal acute muscle 1,A1-7 dorsal acute muscle 2,A1-7 dorsal oblique muscle 1,A1-7 dorsal oblique muscle 2,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,A1-7 VL3/4 motor neuron,A1-7 VO2 motor neuron,A1-7 VO1 motor neuron,motor neuron" DRSC14523 I -1.615638577 2.154429037 0.291326972 0.401677121 -0.200807734 -0.565566288 FBgn0004034 y yellow http://flybase.net/reports/FBgn0004034.html protein_coding_gene 0016853=isomerase activity "0048082=regulation of adult chitin-containing cuticle pigmentation, 0006583=melanin biosynthetic process from tyrosine, 0042438=melanin biosynthetic process, 0048066=developmental pigmentation, 0048067=cuticle pigmentation, 0048065=male courtship behavior, veined wing extension, 0060179=male mating behavior" "0005737=cytoplasm, 0005576=extracellular region, 0070451=cell hair" "EG:125H10.2, CG3757, yellow, T6, Y" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR029846=Protein yellow, IPR017996=Major royal jelly protein/Protein yellow" CG3757 16-Dec-15 2015_12 " larval stage , pupal stage , embryonic stage | stage 15 , embryonic stage | stage 17 , adult stage , embryonic stage | stage 16 " " anal plate

, embryonic/larval esophagus

, cephalopharyngeal skeleton

" " pupal stage , adult stage , embryonic stage | stage 16 , embryonic stage " " epidermis

, cuticle

, embryonic/larval pharynx | anterior

, Keilin's organ

, abdominal segment 1--8

, cephalopharyngeal skeleton

, microchaeta

, denticle belt

" "body color defective,visible,recessive,viable,male,male fertile,mating defective,wild-type,reduced,eye color defective,heat sensitive,male sterile,dominant,small body,female,courtship behavior defective,fertile,behavior defective,cold sensitive,enhancer of variegation" "adult cuticle,wing vein,macrochaeta,wing hair,cuticle,wing,chaeta,wing blade,adult,adult abdomen,adult thorax,macrochaeta & adult thorax,macrochaeta & leg,leg & macrochaeta,antenna,adult cuticle & wing,male,unguis,adult epidermis,wing sensillum,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,adult abdominal sensillum,adult thorax & macrochaeta,leg & external sensory organ,adult abdomen & macrochaeta,sex comb,arista,microchaeta,embryonic/larval mouth,cephalopharyngeal skeleton,mesothoracic bristle,macrochaeta & wing,macrochaeta & adult abdomen,pigment cell,larva,macrochaeta & thorax,macrochaeta & abdomen,head bristle,chaeta & adult thorax,cuticle & abdomen,wing & macrochaeta,mouth hooks,denticle belt,adult cuticle & adult abdomen | female,cold sensitive,scutum,leg,leg sensillum,adult thoracic sensillum,tibia,tarsal segment 2,tarsal segment 3,tarsal segment 4,antennal segment,metatarsus,pretarsus,analia,posterior compartment" FBgn0001569 l(1)20Ca lethal (1) 20Ca http://flybase.net/reports/FBgn0001569.html gene "13E3, unnamed, P19, l(1)13E3, l(1)D-19, section 33, P-19, 33, l(1)P19, l(1)P-19, l13E3" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,rescuable maternal effect,partially" FBgn0003407 sie sieve http://flybase.net/reports/FBgn0003407.html gene 0007349=cellularization 16-Dec-15 2015_12 "female sterile,semidominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,recessive,non-suppressor of variegation,dominant" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0005011 Dipp Defective in phototaxis plasticity http://flybase.net/reports/FBgn0005011.html gene 16-Dec-15 2015_12 "neurophysiology defective,visual behavior defective" photoreceptor FBgn0003978 vls valois http://flybase.net/reports/FBgn0003978.html FBgn0032841 protein_coding_gene "0007349=cellularization, 0007067=mitotic nuclear division, 0009880=embryonic pattern specification, 0007315=pole plasm assembly" "0043186=P granule, 0045495=pole plasm, 0005737=cytoplasm" "CG107278, Valois, val, CG10728, 38B.5" "IPR019775=WD40 repeat, conserved site, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG10728 16-Dec-15 2015_12 ENSG00000116455(WDR77) "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,viable,germline clone,non-rescuable maternal effect,female sterile,grandchildless,male sterile,lethal,partially lethal - majority die,some die during pupal stage" "pole cell,maternal effect,pole plasm | maternal effect,egg,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,embryo,germline clone,posterior,stage 5 embryo,embryonic/first instar larval cuticle,pole granule,embryonic abdominal segment,karyosome,gamete,abdominal segment" FBgn0027552 CG10863 http://flybase.net/reports/FBgn0027552.html protein_coding_gene 0004032=alditol:NADP+ 1-oxidoreductase activity 0055114=oxidation-reduction process "BcDNA:GH10614, dm1/AKR2E3" "IPR001395=Aldo/keto reductase, IPR018170=Aldo/keto reductase, conserved site, IPR020471=Aldo/keto reductase subgroup, IPR023210=NADP-dependent oxidoreductase domain" CG10863 16-Dec-15 2015_12 "YOR120W(GCY1),YDR368W(YPR1)" "viable,visible" mesothoracic tergum FBgn0011096 l(1)Q56 lethal (1) Q56 http://flybase.net/reports/FBgn0011096.html FBgn0010210 gene 16-Dec-15 2015_12 lethal FBgn0002269 l(3)69Ba lethal (3) 69Ba http://flybase.net/reports/FBgn0002269.html gene "rsg31, rose-gespleten region interval 31, l(3)rsg31" 16-Dec-15 2015_12 lethal FBgn0010073 Metatarsi-irregular Metatarsi irregular http://flybase.net/reports/FBgn0010073.html gene Met 16-Dec-15 2015_12 "visible,dominant,chemical resistant" "tarsal segment 1 & joint,tarsal segment 2 & joint,leg sensillum,eye" FBgn0001455 l(1)7Di lethal (1) 7Di http://flybase.net/reports/FBgn0001455.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0002210 l(3)67BDh lethal (3) 67BDh http://flybase.net/reports/FBgn0002210.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,lethal,some die during immature adult stage,recessive" FBgn0025864 Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein http://flybase.net/reports/FBgn0025864.html protein_coding_gene "0017137=Rab GTPase binding, 0017112=Rab guanyl-nucleotide exchange factor activity, 0005516=calmodulin binding, 0005085=guanyl-nucleotide exchange factor activity" "0045175=basal protein localization, 0070831=basement membrane assembly, 0032483=regulation of Rab protein signal transduction, 0090630=activation of GTPase activity, 0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0042998=positive regulation of Golgi to plasma membrane protein transport, 0008105=asymmetric protein localization" "0005886=plasma membrane, 0005938=cell cortex, 0055037=recycling endosome, 0031410=cytoplasmic vesicle" "CJ, CG12737, CRAG, Calmodulin-binding protein related to a Rab3 GDP-GTP exchange protein" "IPR005113=uDENN domain, IPR005112=dDENN domain, IPR023341=MABP domain, IPR001194=DENN domain" CG12737 16-Dec-15 2015_12 "ENSDARG00000059571,ENSDARG00000062721(dennd4a)" WBGene00018681(F52C12.4) ENSXETG00000006641() "ENSMUSG00000038024(Dennd4c),ENSMUSG00000042404(Dennd4b)" "ENSG00000174485(DENND4A),ENSG00000137145(DENND4C)" adult stage "neurophysiology defective,somatic clone,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of larval stage,some die during third instar larval stage,progressive,conditional,some die during larval stage,visible,body color defective,partially lethal - majority die,some die during pupal stage" "rhabdomere | progressive | somatic clone | conditional,trans-Golgi network | somatic clone,follicle cell,somatic clone,mesothoracic tergum" FBgn0027095 Manf Mesencephalic astrocyte-derived neurotrophic factor ortholog http://flybase.net/reports/FBgn0027095.html FBgn0026289 protein_coding_gene "0031175=neuron projection development, 0042417=dopamine metabolic process, 0070050=neuron cellular homeostasis" "0005783=endoplasmic reticulum, 0005576=extracellular region, 0012505=endomembrane system" "anon-EST:ParkEST188, Mesencephalic astrocyte-derived neurotrophic factor, CG7013, ARP-like, DmMANF, DmManf" "IPR018247=EF-Hand 1, calcium-binding site, IPR011001=Saposin-like, IPR019345=Armet protein" CG7013 16-Dec-15 2015_12 ENSDARG00000063177(LOC100330924) WBGene00021888(Y54G2A.23) ENSXETG00000000073(armet) "ENSMUSG00000032575(Manf),ENSMUSG00000039496(Cdnf)" "ENSG00000145050(MANF),ENSG00000185267(CDNF)" "lethal,recessive,lethal - all die during first instar larval stage,locomotor behavior defective,maternal effect,increased cell death,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" "neurite & dopaminergic neuron | larval stage,ventral nerve cord,maternal effect,embryonic/larval cell body glial cell,neuropil,embryonic/first instar larval cuticle" FBgn0010314 Cks30A Cyclin-dependent kinase subunit 30A http://flybase.net/reports/FBgn0010314.html FBgn0003235 protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0005515=protein binding" "0006468=protein phosphorylation, 0035186=syncytial blastoderm mitotic cell cycle, 0051225=spindle assembly, 0007143=female meiotic division, 0007057=spindle assembly involved in female meiosis I, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation, 0007144=female meiosis I, 0007488=histoblast morphogenesis, 0045842=positive regulation of mitotic metaphase/anaphase transition" "cks, Cks, cdi2, remnants, CG3738, cks30A, U40077, rem, fs(2)rem, CDI2, Cdi2, Cyclin-dependent kinase interactor 2, DmCks1" "IPR000789=Cyclin-dependent kinase, regulatory subunit" CG3738 16-Dec-15 2015_12 "ENSDARG00000007971(zgc:101026),ENSDARG00000040494,ENSDARG00000071410(si:dkey-94n12.2)" YBR135W(CKS1) WBGene00001051(cks-1) "ENSXETG00000015421(CKS1B),ENSXETG00000010855(CKS2)" "ENSMUSG00000028044(Cks1b),ENSMUSG00000062687(Gm6531),ENSMUSG00000062248(Cks2)" "ENSG00000173207(CKS1B),ENSG00000178556,ENSG00000123975(CKS2)" "viable,male fertile,lethal,maternal effect,mitotic cell cycle defective,meiotic cell cycle defective,female limited,female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,female,partially lethal - majority die,some die during pupal stage" "aster & oocyte,larval cuticle & larval abdomen,embryonic/first instar larval cuticle,aster,spindle pole centrosome,spindle,spindle & oocyte" FBgn0003891 tud tudor http://flybase.net/reports/FBgn0003891.html protein_coding_gene "0007277=pole cell development, 0007278=pole cell fate determination, 0019090=mitochondrial rRNA export from mitochondrion, 0007281=germ cell development, 0007315=pole plasm assembly, 0008298=intracellular mRNA localization, 0030719=P granule organization" "0005739=mitochondrion, 0005737=cytoplasm, 0045495=pole plasm, 0005634=nucleus, 0043186=P granule" "TUD, tu, Tudor, Tud, CG9450, TUDOR" IPR002999=Tudor domain CG9450 16-Dec-15 2015_12 "ENSDARG00000014039,ENSDARG00000070052" "ENSXETG00000007137(),ENSXETG00000016255(TDRD6)" ENSMUSG00000025081(Tdrd1) "ENSG00000180113(TDRD6),ENSG00000218819" " adult stage && oogenesis stage | stage S10-14 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-3 " " follicle cell | posterior

, germarium

, ovariole

" " oogenesis stage | stage S7-9 , embryonic stage , adult stage && oogenesis stage | stage S10 " " oocyte

,

, vitelline membrane

" "grandchildless,male fertile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,male sterile,germline clone,non-rescuable maternal effect,female sterile,sterile,partially,viable" "pole cell,maternal effect,germline cell,embryonic abdominal segment,gonad,P granule | maternal effect,P granule | maternal effectPF1),spermatozoon,pole granule,abdominal segment,egg,P granulePF1),embryo,germline clone,posterior,pole plasm | maternal effect,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11" FBgn0003388 shd shade http://flybase.net/reports/FBgn0003388.html FBgn0036432 protein_coding_gene "0005506=iron ion binding, 0004501=ecdysone 20-monooxygenase activity, 0009055=electron carrier activity, 0020037=heme binding" "0008258=head involution, 0007494=midgut development, 0007295=growth of a germarium-derived egg chamber, 0007391=dorsal closure, 0007417=central nervous system development, 0007298=border follicle cell migration, 0055114=oxidation-reduction process, 0045456=ecdysteroid biosynthetic process" "0016020=membrane, 0005739=mitochondrion" "shade, cyp314a1, CYP314A1, CG13478, 314a1, ecdysone 20-monooxygenase, Shade, Cyp314a1, cytochrome P450" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG13478 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,female sterile" "presumptive embryonic/larval central nervous system,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,commissure,glial cell,midline glial cell,ectopic,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,embryonic head,embryonic/larval midgut primordium,embryonic dorsal epidermis,epicuticle,embryonic/larval cuticle,egg chamber,border follicle cell,somatic clone,midgut constriction,embryo,embryonic/larval tracheal system" FBgn0005355 Su(fu) Suppressor of fused http://flybase.net/reports/FBgn0005355.html FBgn0003562 protein_coding_gene 0008134=transcription factor binding "0045879=negative regulation of smoothened signaling pathway, 0043433=negative regulation of sequence-specific DNA binding transcription factor activity, 0042994=cytoplasmic sequestering of transcription factor, 0032091=negative regulation of protein binding" "0005737=cytoplasm, 0043234=protein complex, 0035301=Hedgehog signaling complex" "dSufu, suppressor of fused, SuFu, su(fu), SUFU, Suppressor of Fused, CG6054, Sufu, Su(Fu), SU(FU), sufu" "IPR016591=Suppressor of fused, eukaryotic, IPR020941=Suppressor of fused-like domain, IPR007768=Suppressor of fused, IPR024314=Suppressor of fused C-terminal" CG6054 16-Dec-15 2015_12 ENSDARG00000056801(sufu) ENSXETG00000015219(SUFU) ENSMUSG00000025231(Sufu) ENSG00000107882(SUFU) " adult stage | female , embryonic stage "

ubiquitous "viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,wing vein,sensillum campaniformium of dorsal radius,costal vein,axillary vein,wing margin,prothoracic leg,sex comb,supernumerary,metathoracic leg,antenna,wing disc" FBgn0266450 Kr-h1 Kruppel homolog 1 http://flybase.net/reports/FBgn0266450.html "FBgn0028420, FBgn0001326, FBgn0010668, FBgn0024313, FBgn0042122, FBgn0266444" protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0007552=metamorphosis, 0045316=negative regulation of compound eye photoreceptor development, 0035075=response to ecdysone, 0006355=regulation of transcription, DNA-templated, 0010977=negative regulation of neuron projection development" 0005634=nucleus "Passion of white, kruppel homolog 1, 44/11, Kruppel-homolog-1, Pow, CG9167, CG18783, Kr h, Krupple homolog 1, Kruppel-homolog 1, P381, Kr-H1, l(2)05208, l(2)10642, CG45074, Krueppel-homolog alpha-isoform, Kr-h, unnamed" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG45074 16-Dec-15 2015_12 " larval stage | third instar , larval stage | first instar , embryonic stage , embryonic stage -- adult stage , embryonic stage | stage 5-8 , embryonic stage | 20-24 hr , larval stage | second instar , prepupal stage | <=6-8 hr , adult stage , prepupal stage | 6-8 hr , embryonic stage | mid-late " organism

FBgn0004373 fwd four wheel drive http://flybase.net/reports/FBgn0004373.html "FBgn0035129, FBgn0062139" protein_coding_gene 0004430=1-phosphatidylinositol 4-kinase activity "0030726=male germline ring canal formation, 0006661=phosphatidylinositol biosynthetic process, 0007112=male meiosis cytokinesis, 0048015=phosphatidylinositol-mediated signaling, 0016310=phosphorylation, 0048137=spermatocyte division, 0090175=regulation of establishment of planar polarity, 0007030=Golgi organization, 0007110=meiosis I cytokinesis, 0008340=determination of adult lifespan, 0046854=phosphatidylinositol phosphorylation, 0043147=meiotic spindle stabilization, 0007283=spermatogenesis, 0007111=meiosis II cytokinesis, 0000916=actomyosin contractile ring contraction" 0005794=Golgi apparatus "Four wheel drive, Fwd, CG7004, anon-WO0118547.259, PI4K, Four-wheel drive" "IPR018936=Phosphatidylinositol 3/4-kinase, conserved site, IPR011009=Protein kinase-like domain, IPR015433=Phosphatidylinositol Kinase, IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR027003=Phosphatidylinositol 4-kinase" CG7004 16-Dec-15 2015_12 ENSDARG00000040111(pi4kb) "viable,fertile,long lived,meiotic cell cycle defective,male,male sterile,cytokinesis defective,female fertile,recessive,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,lethal" "spermatid & nucleus7C),spermatid,spermatid axoneme,Nebenkern derivative,spermatozoon,Golgi apparatus,spermatid & nucleusemc-E12),Nebenkern,secondary spermatocyte,spindle & meiotic telophase I | male7C),contractile ring & meiotic telophase I | male7C),spindle & meiotic telophase II | male7C),contractile ring & meiotic telophase II | male7C),spermatid & nucleus | supernumerary,wing hair,supernumerary,wing blade" DRSC08580 IE 1.838953122 1.895909477 2.288742922 -0.422595564 0.221880936 0.743956749 FBgn0030089 AP-1ë_ "Adaptor Protein complex 1, ë_ subunit" http://flybase.net/reports/FBgn0030089.html protein_coding_gene 0008565=protein transporter activity "0006886=intracellular protein transport, 0006901=vesicle coating, 0016183=synaptic vesicle coating, 0007269=neurotransmitter secretion, 0033363=secretory granule organization, 0035652=cargo loading into clathrin-coated vesicle, 0048749=compound eye development" "0030135=coated vesicle, 0030141=secretory granule, 0030136=clathrin-coated vesicle, 0030121=AP-1 adaptor complex, 0005802=trans-Golgi network, 0055037=recycling endosome, 0008021=synaptic vesicle" "AP1gamma1, cg9113, gamma, AP1gamma, dgamma, apl4, AP-1, CG9113, Ap-1, gamma-Ada, gamma subunit of AP-1 clathrin, AP-1[gamma], AP-1 gamma, AP-1gamma, gamma-adaptin" "IPR008153=Clathrin adaptor, gamma-adaptin, appendage, IPR008152=Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR013041=Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR017107=Adaptor protein complex AP-1, gamma subunit, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG9113 16-Dec-15 2015_12 "ENSDARG00000012294(ap1g1),ENSDARG00000054337(ap1g2)" YPR029C(APL4) WBGene00000158(apg-1) ENSXETG00000019853(AP1G1) "ENSMUSG00000031731(Ap1g1),ENSMUSG00000040701(Ap1g2)" "ENSG00000166747(AP1G1),ENSG00000213983(AP1G2)" "lethal - all die before end of pupal stage,some die during pupal stage" "tormogen cell,supernumerary,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,trans-Golgi networkAB1,eye,ommatidium" FBgn0017551 Rca1 Regulator of cyclin A1 http://flybase.net/reports/FBgn0017551.html protein_coding_gene 0004842=ubiquitin-protein transferase activity "0022008=neurogenesis, 0000082=G1/S transition of mitotic cell cycle, 0046331=lateral inhibition, 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0007455=eye-antennal disc morphogenesis, 0007088=regulation of mitotic nuclear division, 0060564=negative regulation of APC-Cdc20 complex activity" "0019005=SCF ubiquitin ligase complex, 0005634=nucleus" "regulator of cyclin A, CLD4, rca1, Emi1, Regulator of Cyclin A 1, FBXO5, 152549_at, P3300, Suppressor of rux 2A, S(rux)2A, regulator of Cyclin A, l(2)03300, CG10800, RCA1" CG10800 16-Dec-15 2015_12 " embryonic stage | stage >=8 , embryonic stage | early , embryonic stage | stage 8-9 , embryonic stage | stage >=13 " " anterior midgut proper primordium

,

ubiquitous , posterior midgut proper primordium

, mesoderm

, embryonic nervous system

" "viable,fertile,partially lethal - majority die,lethal,recessive,mitotic cell cycle defective,somatic clone,decreased cell number,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,neuroanatomy defective,visible" "ganglion mother cell GMC4-2a,RP2sib neuron,ganglion mother cell,pCC neuron,aCC neuron,precursor,U neuron,embryonic pericardial cell,abdominal segment 2 & cardioblast,abdominal segment 3 & cardioblast,abdominal segment 4 & cardioblast,abdominal segment 5 & cardioblast,abdominal segment 6 & cardioblast,abdominal segment 7 & cardioblast,ganglion mother cell GMC1-1a,EL neuron,eye,wing disc,somatic clone,nucleus | somatic clone,cardioblast,eye disc posterior to the morphogenetic furrow,embryonic/larval neuroblast,chaeta" DRSC03407 IEK -0.233954906 -1.619027019 1.697755759 -2.828038056 4.390766491 3.394545227 FBgn0011205 fbl fumble http://flybase.net/reports/FBgn0011205.html "FBgn0052429, FBgn0036981" protein_coding_gene "0005524=ATP binding, 0004594=pantothenate kinase activity" "0070328=triglyceride homeostasis, 0007067=mitotic nuclear division, 0007126=meiotic nuclear division, 0040011=locomotion, 0007476=imaginal disc-derived wing morphogenesis, 0007283=spermatogenesis, 0048477=oogenesis, 0006979=response to oxidative stress, 0061024=membrane organization, 0045475=locomotor rhythm, 0007059=chromosome segregation, 0032465=regulation of cytokinesis, 0071480=cellular response to gamma radiation, 0015937=coenzyme A biosynthetic process" "0005737=cytoplasm, 0005819=spindle, 0005886=plasma membrane" "dPanK, CG5725, PANK, pantothenate kinase, Fbl, dPANK, dPANK/Fbl" IPR004567=Type II pantothenate kinase CG5725 16-Dec-15 2015_12 "ENSDARG00000008192(pank1a),ENSDARG00000003311(zgc:158667),ENSDARG00000010098(pank1b)" WBGene00004068(pnk-1) "ENSXETG00000017986(PANK2),ENSXETG00000013675(PANK3)" "ENSMUSG00000033610(Pank1),ENSMUSG00000037514(Pank2),ENSMUSG00000018846(Pank3)" "ENSG00000152782(PANK1),ENSG00000125779(PANK2),ENSG00000120137(PANK3)" "meiotic cell cycle defective,female sterile,recessive,behavior defective,female,uncoordinated,cytokinesis defective,male,male sterile,partially lethal,locomotor behavior defective,flightless,flight defective,short lived,visible,chemical sensitive,radiation sensitive,increased cell death,sterile,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,wild-type,oxidative stress response defective,locomotor rhythm defective,visual behavior defective" "spermatid,spermatocyte & spindle,spermatocyte & aster,Nebenkern derivative,spermatid & nucleus,spermatocyte & centrosome,testis,Nebenkern,wing,adult brain,embryonic/larval brain,ovary,dorsal appendage,maternal effect,egg,anterior crossvein,posterior crossvein,retina,onion stage spermatid,mitotic cell cycle,mitotic metaphase,anaphase & condensed nuclear chromosome,macrochaeta,ectopic" FBgn0062585 Mod(var)1683 Mod(var)1683 http://flybase.net/reports/FBgn0062585.html gene "0006342=chromatin silencing, 0030702=chromatin silencing at centromere" 1683 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0020238 14-3-3ëµ 14-3-3ëµ http://flybase.net/reports/FBgn0020238.html "FBgn0011329, FBgn0016739, FBgn0016743, FBgn0046456, FBgn0051196, FBgn0064146, FBgn0066007" protein_coding_gene "0046982=protein heterodimerization activity, 0005515=protein binding, 0019904=protein domain specific binding, 0008426=protein kinase C inhibitor activity" "0007265=Ras protein signal transduction, 0040008=regulation of growth, 0045927=positive regulation of growth, 0048190=wing disc dorsal/ventral pattern formation, 0007444=imaginal disc development, 0009314=response to radiation, 0007093=mitotic cell cycle checkpoint, 0007411=axon guidance, 0007294=germarium-derived oocyte fate determination, 0070374=positive regulation of ERK1 and ERK2 cascade, 0000077=DNA damage checkpoint, 0008103=oocyte microtubule cytoskeleton polarization, 0009411=response to UV, 0007088=regulation of mitotic nuclear division, 0007095=mitotic G2 DNA damage checkpoint, 0046579=positive regulation of Ras protein signal transduction, 0007280=pole cell migration, 0008340=determination of adult lifespan" "0005634=nucleus, 0005694=chromosome, 0005737=cytoplasm, 0045172=germline ring canal, 0005886=plasma membrane, 0005813=centrosome, 0005654=nucleoplasm, 0005875=microtubule associated complex" "14-3-3-e, CT24092, D14-3-3e, 14-3-3&epsilon, CG31196, par-5, D14-3-3epsilon, e-14-3-3, eps, PAR-5, anon-WO02059370.52, 14-3-3omicron, l(3)j2B10, 14-3-3e, Par-5, anon-WO0172774.141, 143E_DROME, 14.3.3 epsilon, Tyrosine-3-monooxygenase, 14-3-3-epsilon, EK3-5, 14-3-3, SR3-9, Suppressor of Ras85D 3-9, Su(Raf)3B, 1433epsilon, 14-3-3epsilon, 14-3-3 epsilon, 14-3-30epsilon, d14-3-3epsilon, PAR5, Epsilon, 14-3-3EPSILON" "IPR023410=14-3-3 domain, IPR000308=14-3-3 protein, IPR023409=14-3-3 protein, conserved site" CG31196 16-Dec-15 2015_12 "ENSDARG00000006399(ywhae1),ENSDARG00000017014(ywhae2)" "YER177W(BMH1),YDR099W(BMH2)" ENSXETG00000022893(ywhae) ENSMUSG00000020849(Ywhae) ENSG00000108953(YWHAE) " embryonic stage | stage 9-10 , embryonic stage | stage 7,8 , adult stage , embryonic stage | syncytial blastoderm , embryonic stage " " ventral nerve cord primordium

, cephalic furrow

, germarium

, ring canal

, embryonic peripheral nervous system

, amnioproctodeal invagination

, embryonic central nervous system

, ventral midline

, dorsal ectoderm

, posterior transverse furrow

, anterior transverse furrow

" "neuroanatomy defective,lethal,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,viable,sterile,recessive,mitotic cell cycle defective,female sterile,visible,body size defective,radiation sensitive,dominant,long lived,male sterile,partially lethal - majority die,partially,female fertile,male fertile,fertile,poor" "intersegmental nerve branch ISNb of A1-7,pole cell,embryo,germline clone,maternal effect,cycle 14 embryo,embryonic/first instar larval cuticle,oocyte,nurse cell,ectopic,microtubule organizing center & oocyte,oocyte & centrosome,microtubule & oocyte,anterior crossvein,posterior crossvein,segmental nerve branch SNa of A1-7,eye,eye photoreceptor cell,ommatidium" DRSC16370 I -0.565376865 -1.796429721 -0.961766681 -0.134939549 -1.052256199 0.327555361 FBgn0023167 SmD3 Small ribonucleoprotein particle protein SmD3 http://flybase.net/reports/FBgn0023167.html protein_coding_gene 0044822=poly(A) RNA binding "0007417=central nervous system development, 0007067=mitotic nuclear division, 0007422=peripheral nervous system development, 0007052=mitotic spindle organization, 0007517=muscle organ development, 0030182=neuron differentiation, 0045451=pole plasm oskar mRNA localization, 0000398=mRNA splicing, via spliceosome, 0048542=lymph gland development" "0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome, 0045495=pole plasm, 0005634=nucleus" "CG8427, gutfeeling, SYM10, l(2)154/1, smd3, smD3, l(2)131/7, guf2, Small ribonucleoprotein Sm D3, dD3, snRNP Sm D3, guf, gut feeling, Sm D3, l(2)90/37" "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type, IPR027141=Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3" CG8427 16-Dec-15 2015_12 ENSDARG00000013800(snrpd3) YLR147C(SMD3) WBGene00004914(snr-1) ENSXETG00000024918(SNRPD3) ENSMUSG00000020180(Snrpd3) ENSG00000100028(SNRPD3) embryonic stage "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage,viable" "ventral nerve cord,chordotonal organ,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval somatic muscle,embryonic visceral muscle,embryonic/larval lymph gland,imaginal disc,embryonic/larval optic lobe,wing disc,haltere disc,ventral thoracic disc,embryonic/larval brain,embryonic/larval salivary gland,pole cell,maternal effect" DRSC07553 I -0.661107439 2.147955676 -0.659861544 -0.346204654 -1.293801523 -0.394581391 FBgn0029756 CG3309 http://flybase.net/reports/FBgn0029756.html FBgn0043790 protein_coding_gene BEST:LD39762 "IPR024224=DENND6, IPR018307=AVL9/DENND6 domain" CG3309 16-Dec-15 2015_12 "ENSDARG00000011605(fam116b),ENSDARG00000030239(fam116a)" WBGene00018777(F53H1.3) "ENSXETG00000008657(FAM116A),ENSXETG00000023066(FAM116B)" "ENSMUSG00000015377(Fam116b),ENSMUSG00000040818(Fam116a)" "ENSG00000205593(FAM116B),ENSG00000174839(FAM116A)" viable FBgn0065228 l(2)SH2193 lethal (2) SH2193 http://flybase.net/reports/FBgn0065228.html gene l(2)SH2 2193 16-Dec-15 2015_12 "lethal,recessive" FBgn0039431 plum plum http://flybase.net/reports/FBgn0039431.html protein_coding_gene "0045886=negative regulation of synaptic growth at neuromuscular junction, 0016322=neuron remodeling" "0030425=dendrite, 0030424=axon" "CG6490, CT20213, Plum" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG6490 16-Dec-15 2015_12 "neuroanatomy defective,somatic clone,viable,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "gamma Kenyon cell,somatic clone,embryonic/larval neuromuscular junction,transverse nerve,embryonic/larval neuromuscular junction | larval stage" FBgn0000996 dup double parked http://flybase.net/reports/FBgn0000996.html "FBgn0004160, FBgn0022220, FBgn0034016, FBgn0063791" protein_coding_gene 0003677=DNA binding "0007304=chorion-containing eggshell formation, 0006261=DNA-dependent DNA replication, 0051298=centrosome duplication, 0000076=DNA replication checkpoint, 0000281=mitotic cytokinesis, 0042065=glial cell growth, 0042023=DNA endoreduplication, 0019730=antimicrobial humoral response, 0007307=eggshell chorion gene amplification, 0021782=glial cell development, 0006260=DNA replication" "0005634=nucleus, 0005664=nuclear origin of replication recognition complex, 0005737=cytoplasm, 0005657=replication fork" "fs(2)PA77, double-parked, l(2)51Ec, fs(2)ltoPA77, DUP, Double Parked, double park, cdt1, 19k, fs(2)51Fa, Double-parked, doubleparked, lethal(2)51Ec, Dup, CG8171, Cdt1, l(2)k03308, female sterile(2)51Fa, anon-WO0257455.31, CDT1, double parked, CDT1/DUP, speckled, Double parked, DUP/CDT1, cdt1/dup" IPR014939=CDT1 Geminin-binding domain-like CG8171 16-Dec-15 2015_12 ENSDARG00000051854(cdt1) WBGene00000413(cdt-1) ENSXETG00000011255(CDT1) ENSMUSG00000006585(Cdt1) ENSG00000167513(CDT1) "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,cytokinesis defective,increased cell death,female sterile,maternal effect,neuroanatomy defective,increased cell size,endomitotic cell cycle defective,decreased cell size" "imaginal disc,mitotic cell cycle,S phase | embryonic cycle 16,cycle 16 embryo,mitosis & nuclear chromosome,mitotic metaphase,S phase,metaphase plate,kinetochore | maternal effect,follicle cell,eye disc,embryonic/larval brain | third instar larval stage,embryonic/larval glial cell | third instar larval stage,subperineurial glial cell,embryonic/larval neuroblast,ectopic | third instar larval stage" DRSC07088 IEK -1.833129236 -3.906995979 -4.172235799 -6.712987859 5.494449105 10.08728796 FBgn0003967 vam vacuolar medulla http://flybase.net/reports/FBgn0003967.html gene "Vacuolar medulla, Vam" 16-Dec-15 2015_12 "neurophysiology defective,neuroanatomy defective,optomotor response defective" "medulla,lamina,lobula,brain,lamina monopolar neuron L1,lamina monopolar neuron L2" FBgn0086222 sheepish sheepish http://flybase.net/reports/FBgn0086222.html gene 0046693=sperm storage 16-Dec-15 2015_12 "male sterile,recessive" FBgn0010808 l(3)03670 lethal (3) 03670 http://flybase.net/reports/FBgn0010808.html "FBgn0015363, FBgn0027990" protein_coding_gene "pMY8, 1274/08, l(3)3670, CG1715, x94917, 0353/13, anon-l, 0812/02, 0966/01, 0205/14, l(3)96601, l(3)S127408" CG1715 16-Dec-15 2015_12 WBGene00010942(M176.3) "ENSMUSG00000030086(Chchd6),ENSMUSG00000053768(Chchd3)" "ENSG00000159685(CHCHD6),ENSG00000106554(CHCHD3)" adult stage "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,viable" DRSC16981 E -0.569093387 -0.243250154 -0.33140152 -2.435481629 0.079139689 0.462181033 FBgn0024194 rasp rasp http://flybase.net/reports/FBgn0024194.html "FBgn0002450, FBgn0004562, FBgn0005227, FBgn0035406, FBgn0044333" protein_coding_gene "0016746=transferase activity, transferring acyl groups, 0016409=palmitoyltransferase activity" "0007224=smoothened signaling pathway, 0007367=segment polarity determination, 0018345=protein palmitoylation, 0018009=N-terminal peptidyl-L-cysteine N-palmitoylation, 0046843=dorsal appendage formation, 0007225=patched ligand maturation" "0016021=integral component of membrane, 0005886=plasma membrane" "lethal(3)63Bg, sit, cnm, CG11495, central missing, ski/sit, sightless, l(3)M47, RASP, l(3)63Bg, sig/ski, rsp, 7F21, l(3)m47, Rasp, lethal(3)SG3, skinny hedgehog, ski, cmn, l(3)SG3" "IPR004299=Membrane bound O-acyl transferase, MBOAT" CG11495 16-Dec-15 2015_12 "ENSDARG00000005139(hhatlb),ENSDARG00000039051(hhatla)" "YPL189W(GUP2),YGL084C(GUP1)" WBGene00013852(hhat-1) ENSXETG00000000222(HHAT) ENSMUSG00000037375(Hhat) ENSG00000054392(HHAT) "lethal,visible,recessive,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,segment polarity phenotype,wild-type,maternal effect,germline clone,lethal - all die before end of larval stage,some die during larval stage,viable" "dorsal appendage,germline clone,maternal effect,eye,somatic clone,wing,embryo,embryonic/first instar larval cuticle,wing disc,wing vein L2,wing vein L3,wing vein L4,wing vein L5,eye disc,photoreceptor cell,cell non-autonomous,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,eye-antennal disc,ventral thoracic disc,imaginal disc,wing vein" FBgn0011761 dhd deadhead http://flybase.net/reports/FBgn0011761.html protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0015036=disulfide oxidoreductase activity" "0006662=glycerol ether metabolic process, 0006974=cellular response to DNA damage stimulus, 0007143=female meiotic division, 0045454=cell redox homeostasis, 0060322=head development" 0005634=nucleus "Trx-1, 4193, Dhd, Deadhead, thioredoxin, thioredoxin-like, Dmdhd, DmTrx-1, CG4193, Dmeldhd" "IPR017937=Thioredoxin, conserved site, IPR013766=Thioredoxin domain, IPR005746=Thioredoxin, IPR012336=Thioredoxin-like fold" CG4193 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage >=S9 , embryonic stage | early , adult stage | male , adult stage | female " " nurse cell

,

ubiquitous " "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,female sterile,wild-type,lethal,viable,visible" "embryo,maternal effect,embryonic head,blastoderm embryo,gastrula embryo,pronucleus | maternal effect,polar body nucleus,lateral process,cephalopharyngeal skeleton,chaeta,supernumerary" FBgn0013720 pck pickel http://flybase.net/reports/FBgn0013720.html "FBgn0001369, FBgn0025384, FBgn0027323, FBgn0027333" protein_coding_gene "0060857=establishment of glial blood-brain barrier, 0035151=regulation of tube size, open tracheal system, 0035002=liquid clearance, open tracheal system, 0007424=open tracheal system development, 0019991=septate junction assembly" "0016021=integral component of membrane, 0005918=septate junction" "megatrachea, mega, Mega, Pck, Megatrachea, EG:80H7.2, CG14779, PCK, l(1)G0044" IPR004031=PMP-22/EMP/MP20/Claudin superfamily CG14779 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "transverse connective primordium,dorsal trunk primordium,pleated septate junction & tracheal system,embryonic/larval dorsal trunk,embryonic/larval trachea,embryonic/larval tracheal system,trachea,embryonic dorsal trunk & cell,embryonic/larval transverse connective,cuticle,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt" FBgn0014269 prod proliferation disrupter http://flybase.net/reports/FBgn0014269.html FBgn0034409 protein_coding_gene 0003682=chromatin binding "0007076=mitotic chromosome condensation, 0042752=regulation of circadian rhythm, 0048542=lymph gland development" "0010369=chromocenter, 0005694=chromosome, 0005721=pericentric heterochromatin, 0000792=heterochromatin, 0005719=nuclear euchromatin, 0000775=chromosome, centromeric region" "PROD, CG18608, l(2)k08810, Prod, l(2)88/10" IPR028002=Myb/SANT-like DNA-binding domain CG18608 16-Dec-15 2015_12 embryonic stage -- adult stage " adult stage , larval stage , embryonic stage "

ubiquitous "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,hyperplasia,viable,fertile,wild-type,partially,semi-sterile,visible,locomotor rhythm defective" "imaginal disc,embryonic/larval lymph gland,embryonic/larval brain,leg & adult cuticle | somatic clone,adult cuticle,somatic clone,leg & macrochaeta | somatic clone,macrochaeta,mitosis & nuclear chromosome,eye-antennal disc,eye" FBgn0082304 Rfx2 Rfx2 http://flybase.net/reports/FBgn0082304.html gene 0003677=DNA binding "0006355=regulation of transcription, DNA-templated" "dRFX2, drfx2" "IPR003150=DNA-binding RFX-type winged-helix domain, IPR011991=Winged helix-turn-helix DNA-binding domain" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,visible,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" "melanotic mass,chaeta,eye,ommatidium,eye disc" FBgn0039111 Plip PTEN-like phosphatase http://flybase.net/reports/FBgn0039111.html protein_coding_gene "0004439=phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0022008=neurogenesis, 0016311=dephosphorylation, 0046855=inositol phosphate dephosphorylation, 0006470=protein dephosphorylation" 0005739=mitochondrion "dPTEN, PLIP, MKP-like, plip, CG10371, 150466_at" "IPR000387=Tyrosine specific protein phosphatases domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR024950=Dual specificity phosphatase" CG10371 16-Dec-15 2015_12 ENSDARG00000013860(ptpmt1) WBGene00009207(F28C6.8) ENSXETG00000019931(PTPMT1) ENSMUSG00000063235(Ptpmt1) ENSG00000110536(PTPMT1) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0010356 Taf5 TBP-associated factor 5 http://flybase.net/reports/FBgn0010356.html FBgn0033563 protein_coding_gene 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly "0045944=positive regulation of transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0007221=positive regulation of transcription of Notch receptor target, 0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis" "0005669=transcription factor TFIID complex, 0005634=nucleus" "Taf[[II]]80, TAF[[II]]85, d80, TAF, dTAF[[II]]80, TFIID, dTAF5, dTAFII85, dmTAF5, p85, TBP-associated factor, Taf85, TAF[[II]]80/85, TAF[II]80, TAF[[II]], TAF80, TBP-associated factor 80, Taf80, TAFII85, TAF[[II]]80, TAF80/85, dTAFii80, TFIID 85, TAF5, dmTaf5, CG7704, TAFII80, TBP associated factor 80, TBP-associated factor 80kD" "IPR007582=TFIID subunit, WD40-associated region, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG7704 16-Dec-15 2015_12 ENSDARG00000018325(taf5) YBR198C(TAF5) WBGene00006386(taf-5) ENSXETG00000011394(TAF5) ENSMUSG00000025049(Taf5) ENSG00000148835(TAF5) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC07562 IK -2.007286284 0.831044293 -0.471737886 0.070591137 2.680770546 2.044664495 FBgn0047338 CG32148 http://flybase.net/reports/FBgn0047338.html "FBgn0045223, FBgn0052148" protein_coding_gene "BcDNA:AT21341, NEST:bs21b09" CG32148 16-Dec-15 2015_12 viable DRSC28787 K -0.64396536 0.655734334 -0.183471322 0.996074183 -0.613123327 2.195369706 FBgn0004400 rhi rhino http://flybase.net/reports/FBgn0004400.html FBgn0034254 protein_coding_gene 0003682=chromatin binding "0034587=piRNA metabolic process, 0030381=chorion-containing eggshell pattern formation, 0051276=chromosome organization, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0000792=heterochromatin, 0000785=chromatin, 0005634=nucleus" "RHI, Rhi, rno, CG10683, Rhino, HP1d, HP1D, rhino" "IPR016197=Chromo domain-like, IPR000953=Chromo/chromo shadow domain, IPR023780=Chromo domain" CG10683 16-Dec-15 2015_12 "female sterile,recessive,viable,fertile,female fertile" "nurse cell & chromatin,egg chamber,nurse cell,dorsal appendage,egg,maternal effect" FBgn0035153 ebd1 earthbound 1 http://flybase.net/reports/FBgn0035153.html FBgn0044454 protein_coding_gene 0003677=DNA binding "0030177=positive regulation of Wnt signaling pathway, 0007527=adult somatic muscle development" "Ebd1, CG3371, EP3592, unnamed, Earthbound, Earthbound 1" "IPR007889=DNA binding HTH domain, Psq-type, IPR009057=Homeodomain-like, IPR006600=HTH CenpB-type DNA-binding domain" CG3371 16-Dec-15 2015_12 "ENSMUSG00000044390(Tigd3),ENSMUSG00000047819(Tigd4),ENSMUSG00000068267(Cenpb)" "ENSG00000173825(TIGD3),ENSG00000169989(TIGD4)" "viable,neuroanatomy defective" "dorsal medial muscle,indirect flight muscle,anterior fascicle & synapse,intersegmental nerve" DRSC08565 E -0.507399311 0.482778218 0.480277595 -1.897574842 0.179935432 -0.65174558 FBgn0024192 sag semang http://flybase.net/reports/FBgn0024192.html gene "0007462=R1/R6 cell fate commitment, 0007424=open tracheal system development, 0048557=embryonic digestive tract morphogenesis, 0007465=R7 cell fate commitment, 0042676=compound eye cone cell fate commitment, 0001752=compound eye photoreceptor fate commitment, 0001700=embryonic development via the syncytial blastoderm, 0007422=peripheral nervous system development" 16-Dec-15 2015_12 "lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,rescuable maternal effect,germline clone" "eye photoreceptor cell,eye,ommatidium,eye disc,photoreceptor cell R7,somatic clone,pigment granule | somatic clone,rhabdomere,mitotic cell cycle & eye disc,anal pad,germline clone,embryonic abdominal segment 8,cephalopharyngeal skeleton,midgut constriction,presumptive embryonic/larval peripheral nervous system,embryonic/larval trachea,chordotonal organ,external sensory organ,wing vein L4,cone cell,pigment cell,photoreceptor cell R1,photoreceptor cell R6" FBgn0011726 tsr twinstar http://flybase.net/reports/FBgn0011726.html "FBgn0011567, FBgn0020533, FBgn0020539, FBgn0022163, FBgn0024209" protein_coding_gene 0003779=actin binding "0007409=axonogenesis, 0036011=imaginal disc-derived leg segmentation, 0010591=regulation of lamellipodium assembly, 0008585=female gonad development, 0030042=actin filament depolymerization, 0016319=mushroom body development, 0000902=cell morphogenesis, 0000915=actomyosin contractile ring assembly, 0042067=establishment of ommatidial planar polarity, 0007298=border follicle cell migration, 0000281=mitotic cytokinesis, 0042052=rhabdomere development, 0030041=actin filament polymerization, 0007015=actin filament organization, 0048749=compound eye development, 0001745=compound eye morphogenesis, 0001736=establishment of planar polarity, 0001737=establishment of imaginal disc-derived wing hair orientation" "0005875=microtubule associated complex, 0015629=actin cytoskeleton, 0005829=cytosol, 0005654=nucleoplasm" "cofilin/ADF, ADFcofilin, no terminal filament, T8, cofilin/actin depolymerizing factor homolog, Cofilin/actin depolymerizing factor-like, Tsr, ADF/cofilin, Adf, l(2)k13409, DCofilin, ADF, CG4254, Cofilin, cofilin, l(2)k05633, ntf, D61, twin star, D-cof, Cadf, Twinstar, actin-depolymerizing factor, 12/8, l(2)03101, l(2)k03101" "IPR002108=Actin-depolymerising factor homology domain, IPR029006=ADF-H/Gelsolin-like domain, IPR017904=ADF/Cofilin/Destrin" CG4254 16-Dec-15 2015_12 "ENSDARG00000021124(cfl2l),ENSDARG00000014106(cfl2),ENSDARG00000012972(cfl1)" YLL050C(COF1) WBGene00006794(unc-60) "ENSXETG00000003016(BC091019.1),ENSXETG00000026161(cfl1),ENSXETG00000012301(cfl2)" "ENSMUSG00000015932(Dstn),ENSMUSG00000056201(Cfl1),ENSMUSG00000062929(Cfl2)" "ENSG00000172757(CFL1),ENSG00000165410(CFL2),ENSG00000125868(DSTN)" embryonic stage -- adult stage "neuroanatomy defective,somatic clone,lethal,sterile,partially lethal - majority die,some die during pupal stage,partially lethal - majority live,male sterile,heat sensitive,female sterile,viable,male fertile,partially,lethal - all die before end of pupal stage,recessive,wild-type,visible,cytokinesis defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,cell polarity defective" "adult mushroom body,somatic clone,terminal filament,heat sensitive,chaeta,ovary,actin filament | heat sensitive,border follicle cell,nurse cell & nucleus,eye,retina,optic lobe,lamina,rhabdomereGMR.Pc, tsrëÓ96,rhabdomere membraneGMR.Pc, tsrëÓ96,ommatidium,rhabdomereGMR.Pc,rhabdomere membraneGMR.Pc,rhabdomere,actin cytoskeleton & eye disc | somatic clone,imaginal disc,Nebenkern,spermatid,aster & primary spermatocyte cyst,meiotic prophase I,aster & secondary spermatocyte,meiotic prophase II,spermatocyte ring canal,spermatocyte fusome,oocyte & actin filament | ectopic | germ-line clone,follicle cell & actin filament | ectopic | somatic clone,follicle cell,adult mushroom body & axon | somatic clone,wing hair,filamentous actin | somatic clone,actomyosin contractile ring,microchaeta,wing & filamentous actin, with tsr139.cBa, tsrV27Q.cBa,adult abdominal sensillum,leg sensillum,bract,wing & filamentous actin,rhabdomereGMR.Pc, tsrUAS.cPa,rhabdomere membraneGMR.Pc, tsrUAS.cPa,wing & filamentous actin, with tsrëÓ96, tsrV27Q.cBa,wing & filamentous actin, with tsrëÓ96, tsr139.cBa,adult olfactory receptor neuron Or59c,dendrite109(2)80" DRSC04718 K -0.234560469 1.041267168 1.048872533 -0.339004784 2.595206503 2.403453655 FBgn0004242 Syt1 Synaptotagmin 1 http://flybase.net/reports/FBgn0004242.html "FBgn0005767, FBgn0022151" protein_coding_gene "0005515=protein binding, 0005544=calcium-dependent phospholipid binding, 0005509=calcium ion binding, 0000149=SNARE binding, 0001786=phosphatidylserine binding, 0042803=protein homodimerization activity" "0016079=synaptic vesicle exocytosis, 0050803=regulation of synapse structure or activity, 0048488=synaptic vesicle endocytosis, 0060024=rhythmic synaptic transmission, 0008345=larval locomotory behavior, 0031340=positive regulation of vesicle fusion, 0006887=exocytosis, 0048791=calcium ion-dependent exocytosis of neurotransmitter, 0007269=neurotransmitter secretion, 1900073=regulation of neuromuscular synaptic transmission, 0007317=regulation of pole plasm oskar mRNA localization, 0007268=synaptic transmission, 0048489=synaptic vesicle transport, 0016192=vesicle-mediated transport" "0043195=terminal bouton, 0008021=synaptic vesicle, 0031594=neuromuscular junction, 0016021=integral component of membrane, 0030285=integral component of synaptic vesicle membrane, 0016020=membrane" "Synaptotagmin1, SYT1, DSYT2, Synaptotagmin-1, syt1, l(2)23AB1, Synaptoptagmin 1, Synaptotagmin I, unnamed, DSyt1, synaptotagmin, Synaptotagmin 1, CG3139, dSyt1, DSYT, SYT I, synaptotagmin I, dSYT, Syt, dsyt1, Syt1, Synaptotagmin, dsytI, STY1, l(2)23Ba, syt 1, syt-1, syt, l(2)k05909, syt I, synaptotagmin 1, SytI, D. Syt I, synaptotagmin-1, Syt 1, sytI, Syt-1, DSyt, SynaptotagminI, Syt I, Synaptotagmin-I, Dsyt2, Droso1, DSypt, SYT" "IPR000008=C2 domain, IPR015428=Synaptotagmin 1, IPR001565=Synaptotagmin" CG3139 16-Dec-15 2015_12 "ENSDARG00000030614(syt1a),ENSDARG00000025206,ENSDARG00000042350(syt1b),ENSDARG00000014169(LOC559637),ENSDARG00000011640(syt5b),ENSDARG00000037941(syt5a)" WBGene00004921(snt-1) "ENSXETG00000004068(SYT1),ENSXETG00000003212(SYT5),ENSXETG00000017094(SYT2)" "ENSMUSG00000035864(Syt1),ENSMUSG00000026452(Syt2)" "ENSG00000067715(SYT1),ENSG00000143858(SYT2)" " embryonic stage |>8-12 hr , embryonic stage | stage >=13 , adult stage , embryonic stage | stage 17 , embryonic stage -- adult stage , embryonic stage | stage 15-17 , larval stage--pupal stage , embryonic stage | 12-20 hr , embryonic stage | stage >15 " " embryonic central nervous system

, adult head

, central nervous system

, thoracico-abdominal ganglion

, embryonic peripheral nervous system

, adult brain

, ventral nerve cord

" " larval stage , embryonic stage | stage 16 , embryonic stage | stage 14-17 , embryonic stage | stage 17 , larval stage | third instar , larval stage | first instar , embryonic stage , larval stage | second instar , adult stage , larval stage--adult stage " " neuromuscular junction

, motor neuron

, central nervous system | restricted

, neuropil

, optic neuropil

, synapse

,synapse

, embryonic peripheral nervous system | restricted

" "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,behavior defective,lethal - all die before end of larval stage,some die during larval stage,uncoordinated,locomotor rhythm defective,some die during third instar larval stage,wild-type,conditional,flightless,neuroanatomy defective,viable,flight defective,locomotor behavior defective" "crystal cell,neuromuscular junction,synapse | larval stage,synaptic vesicle,synapseelav.PLu,egg,germline clone,synaptic vesicle | third instar larval stage,synaptic vesicleelav.PLu, Syt1KQ.UAS,synaptic vesicleelav.PLu, Syt1AD4, Syt1KQ.UAS,embryonic/larval neuromuscular junction,synapse | embryonic stage,eye,somatic clone,photoreceptor cell & synapse,bouton,supernumerary,synapse,neuron,synaptic vesicleelav.PLu, Syt1KQ.UAS, Syt1N13,wing,synaptic vesicleelav.PLu, Syt1AD4/Syt1N13,synaptic vesicleelav.PLu, Syt1AD4, Syt1N13" DRSC00156 I -2.270164249 0.827424096 0.194495777 -0.73538698 0.316217495 -0.383072571 FBgn0005346 Scarred Scarred http://flybase.net/reports/FBgn0005346.html gene Scar 16-Dec-15 2015_12 "visible,dominant,heat sensitive,lethal,recessive" "eye,heat sensitive,wing" FBgn0028040 l(3)S099312 lethal (3) S099312 http://flybase.net/reports/FBgn0028040.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0035106 rno rhinoceros http://flybase.net/reports/FBgn0035106.html protein_coding_gene "0003677=DNA binding, 0008270=zinc ion binding" "0042051=compound eye photoreceptor development, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "unnamed, Rhinoceros, CG7036" "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR019787=Zinc finger, PHD-finger, IPR019542=Enhancer of polycomb-like, N-terminal, IPR019786=Zinc finger, PHD-type, conserved site" CG7036 16-Dec-15 2015_12 "lethal,recessive,increased cell number,somatic clone,decreased cell death,viable,visible" "photoreceptor cell R8,somatic clone,photoreceptor cell,cone cell,ommatidium,arista,leg,ectopic,ommatidium & photoreceptor | ectopic | somatic clone,ommatidium & photoreceptor | ectopic | somatic clone | cell non-autonomous,photoreceptor cell R3,photoreceptor cell R4,pigment cell,interommatidial bristle | P-stage,pigment cell | P-stage,eye,rhabdomereGMR.PF,mesothoracic tergum" DRSC08584 K -0.818149608 0.129538168 -0.946593527 0.979555488 0.359932768 1.873059763 FBgn0263598 Vha68-2 Vacuolar H+ ATPase 68 kDa subunit 2 http://flybase.net/reports/FBgn0263598.html "FBgn0020367, FBgn0010494, FBgn0010694, FBgn0032463, FBgn0260570" protein_coding_gene "0005524=ATP binding, 0046961=proton-transporting ATPase activity, rotational mechanism" "0016197=endosomal transport, 0048388=endosomal lumen acidification, 0007446=imaginal disc growth, 0015991=ATP hydrolysis coupled proton transport, 0046034=ATP metabolic process" "0005886=plasma membrane, 0033181=plasma membrane proton-transporting V-type ATPase complex, 0000221=vacuolar proton-transporting V-type ATPase, V1 domain" "RE30552p, Vha68.2, ATP6V1A, Vha68-2, l(2)s4214, vha68-2, Vacuolar H[+] ATPase subunit 68-2, MENE-R6, Vha68, vacuolar ATPase, V-ATPase 69 kDa subunit 2, l(2)01510, A subunit, CG3762, vha67-2" "IPR000194=ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000793=ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal, IPR024034=ATPase, F1 complex beta subunit/V1 complex, C-terminal, IPR022878=V-type ATP synthase catalytic alpha chain, IPR020003=ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR005725=ATPase, V1 complex, subunit A, IPR004100=ATPase, F1 complex alpha/beta subunit, N-terminal domain" CG3762 16-Dec-15 2015_12 ENSDARG00000034534(atp6v1al) WBGene00013025(vha-13) ENSXETG00000009908(atp6v1a) ENSMUSG00000052459(Atp6v1a) ENSG00000114573(ATP6V1A) FBgn0053823 His2A:CG33823 His2A:CG33823 http://flybase.net/reports/FBgn0053823.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33823 "IPR002119=Histone H2A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33823 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0053890 His2B:CG33890 His2B:CG33890 http://flybase.net/reports/FBgn0053890.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33890 "IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33890 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0037884 Arfip Arfaptin http://flybase.net/reports/FBgn0037884.html protein_coding_gene "0019904=protein domain specific binding, 0005543=phospholipid binding, 0034452=dynactin binding, 0070273=phosphatidylinositol-4-phosphate binding" "0048149=behavioral response to ethanol, 0045887=positive regulation of synaptic growth at neuromuscular junction" "0032588=trans-Golgi network membrane, 0005802=trans-Golgi network" "partner of Rac1, arfaptin-2, arfaptin, arfip, CG17184, dCG17184-PA" "IPR030798=Arfaptin family, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR010504=Arfaptin homology (AH) domain" CG17184 16-Dec-15 2015_12 "ENSDARG00000056664(arfip2b),ENSDARG00000059244(arfip2a),ENSDARG00000070055(arfip1)" WBGene00010040(F54C8.7) "ENSXETG00000016435(ARFIP2),ENSXETG00000001840(arfip1)" "ENSMUSG00000030881(Arfip2),ENSMUSG00000074513(Arfip1)" "ENSG00000132254(ARFIP2),ENSG00000164144(ARFIP1)" "viable,fertile,neuroanatomy defective,partially lethal,some die during pupal stage,chemical sensitive,recessive" "neurite | pharate adult stage,NMJ bouton,Golgi apparatus,supernumerary | third instar larval stage" FBgn0031491 ë±4GT1 ë±4GT1 http://flybase.net/reports/FBgn0031491.html protein_coding_gene "0035248=alpha-1,4-N-acetylgalactosaminyltransferase activity, 0008376=acetylgalactosaminyltransferase activity" "0009247=glycolipid biosynthetic process, 0006688=glycosphingolipid biosynthetic process, 0043066=negative regulation of apoptotic process, 0006664=glycolipid metabolic process, 0045747=positive regulation of Notch signaling pathway" "alpha1,4-N-acetylgalactosaminyltransferase-1, CG17223, alpha-4GT1" "IPR007577=Glycosyltransferase, DXD sugar-binding motif, IPR029044=Nucleotide-diphospho-sugar transferases, IPR007652=Alpha 1,4-glycosyltransferase domain" CG17223 16-Dec-15 2015_12 "ENSXETG00000027419(A4GALT),ENSXETG00000022707(),ENSXETG00000022706(),ENSXETG00000004687(),ENSXETG00000008304(),ENSXETG00000005012(),ENSXETG00000024912()" "ENSMUSG00000047878(A4galt),ENSMUSG00000037953(A4gnt)" "ENSG00000128274,ENSG00000118017(A4GNT)" viable FBgn0264560 garz gartenzwerg http://flybase.net/reports/FBgn0264560.html "FBgn0033714, FBgn0063599, FBgn0000081" protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0005086=ARF guanyl-nucleotide exchange factor activity" "0035158=regulation of tube diameter, open tracheal system, 0006888=ER to Golgi vesicle-mediated transport, 0007431=salivary gland development, 0000902=cell morphogenesis, 0009306=protein secretion, 0032012=regulation of ARF protein signal transduction, 0002064=epithelial cell development, 0035149=lumen formation, open tracheal system, 0007030=Golgi organization, 0006891=intra-Golgi vesicle-mediated transport, 0043087=regulation of GTPase activity, 0006909=phagocytosis, 0032940=secretion by cell" "0005801=cis-Golgi network, 0000137=Golgi cis cisterna, 0005798=Golgi-associated vesicle" "ArfGEF, GBF1, sec7-family GEF, ARF1GEF, Gartenzwerg, angle wing, CG8487, angina, GEF, ang, Garz, CG 8487" "IPR023394=Sec7 domain, alpha orthogonal bundle, IPR000904=Sec7 domain" CG8487 16-Dec-15 2015_12 ENSDARG00000027016 "YEL022W(GEA2),YJR031C(GEA1)" WBGene00007703(gbf-1) ENSXETG00000010019(GBF1) ENSMUSG00000025224(Gbf1) ENSG00000107862(GBF1) FBgn0005612 Sox14 Sox box protein 14 http://flybase.net/reports/FBgn0005612.html FBgn0034949 protein_coding_gene "0043565=sequence-specific DNA binding, 0008301=DNA binding, bending, 0003700=sequence-specific DNA binding transcription factor activity" "0016322=neuron remodeling, 0006357=regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis, 0007552=metamorphosis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "SOX60B, Dsox-14, DSox14, DSox60B, SOXC, DSox-14, CG3090, sox14, SOX14, CG17263, sox box protein 14" IPR009071=High mobility group box domain CG3090 16-Dec-15 2015_12 " pupal stage , embryonic stage , embryonic stage | 8-24 hr , pupal stage | late , adult stage " " embryonic stage , larval stage | third instar " "lethal,decreased cell death,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,somatic clone,lethal - all die before end of pupal stage" "anterior pupal spiracle,adult abdomen,dendriteppk.1.9,dorsal multidendritic neuron ddaC,mesothoracic tergum,somatic clone,dendrite,dendriteBSC136),dendrite | somatic clone,dendriteor-BR11),dendrite221" DRSC04656 I -0.148463283 -2.172459054 0.219036488 0.534234455 -0.783993735 1.453511322 FBgn0040505 Alk Anaplastic lymphoma kinase http://flybase.net/reports/FBgn0040505.html FBgn0034146 protein_coding_gene "0004716=receptor signaling protein tyrosine kinase activity, 0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0005524=ATP binding" "0043410=positive regulation of MAPK cascade, 0042051=compound eye photoreceptor development, 0090328=regulation of olfactory learning, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007411=axon guidance, 0045792=negative regulation of cell size, 0006468=protein phosphorylation, 0007522=visceral muscle development, 0040008=regulation of growth, 0048565=digestive tract development, 0045610=regulation of hemocyte differentiation, 1900074=negative regulation of neuromuscular synaptic transmission, 0007498=mesoderm development, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0000186=activation of MAPKK activity" "0061176=type Ib terminal bouton, 0071212=subsynaptic reticulum, 0061177=type Is terminal bouton, 0005886=plasma membrane" "CG8250, Alk, Anaplastic lymphoma kinase, mili, DAlk53, ALK, DAlk, Anaplastic Lymphoma Kinase, alk, anaplastic lymphoma kinase, dALK" "IPR017441=Protein kinase, ATP binding site, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR000998=MAM domain, IPR000719=Protein kinase domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR002011=Tyrosine-protein kinase, receptor class II, conserved site, IPR008266=Tyrosine-protein kinase, active site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG8250 16-Dec-15 2015_12 "ENSDARG00000042861(ltk),ENSDARG00000042006" WBGene00004740(scd-2) ENSXETG00000000055(ALK) "ENSMUSG00000055471(Alk),ENSMUSG00000027297(Ltk)" "ENSG00000171094(ALK),ENSG00000062524(LTK)" "lethal,heat sensitive,neurophysiology defective,neuroanatomy defective,somatic clone,recessive,locomotor rhythm defective,cell migration defective,increased cell death,size defective,decreased cell size,learning defective,viable,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage,increased cell size" "midgut,embryonic/larval gut | first instar larval stage,visceral mesoderm,embryonic myoblast,muscle founder cell,axon & photoreceptor cell R8 | somatic clone,optic cartridge,somatic clone,embryonic/larval digestive system,embryonic/larval midgut,neuromuscular junction,longitudinal visceral muscle primordium,muscle founder cell & visceral muscle primordium | ectopic,muscle founder cell & visceral muscle primordium,embryonic somatic muscle,ectopic,muscle founder cell & circular visceral muscle primordium,hemocyte,wing,muscle founder cell & visceral mesodermtwi.PG,embryonic visceral muscle,lamellocyte,wing disc,muscle founder cell & visceral muscle primordiumtwi.2PE,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0028991 seq sequoia http://flybase.net/reports/FBgn0028991.html "FBgn0002074, FBgn0033803, FBgn0033804, FBgn0061357, FBgn0064120" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0045467=R7 cell development, 0060446=branching involved in open tracheal system development, 0007423=sensory organ development, 0035154=terminal cell fate specification, open tracheal system, 0007411=axon guidance, 0045463=R8 cell development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis, 0048666=neuron development" "0005634=nucleus, 0005654=nucleoplasm" "2R5, 49Fc, CG4037, lethal(2)49Fc, l(2)vr5, l(2)49Fc, vr5, Seq, CG4055, CG32904, CG17724b, Sequoia" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG32904 16-Dec-15 2015_12 embryonic stage | stage 3-16 nervous system

" embryonic stage | stage 3-16 , adult stage " " nervous system && neuron && thecogen cell

, head && neuron

" "neuroanatomy defective,somatic clone,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,dominant" "photoreceptor cell R7,somatic clone,photoreceptor cell R8,medulla layer M6,medulla layer M1,medulla layer M2,medulla layer M3,embryonic/larval ganglionic branch,dendrite | dorsal | embryonic stage,embryonic peripheral nervous system & multidendritic neuron,embryonic peripheral nervous system & multidendritic neuron | supernumerary,embryonic peripheral nervous system & multidendritic dendrite | ectopic,embryonic peripheral nervous system & axon,embryonic central nervous system & axon,embryonic peripheral nervous system & sensory neuron,motor neuron & axon & embryo,mesothoracic tergum & adult peripheral nervous system & sensory neuron | somatic clone,scutellum & adult peripheral nervous system & sensory neuron | somatic clone,photoreceptor cell & axon | somatic clone,presumptive embryonic/larval peripheral nervous system,dorsal,axon | dorsal | embryonic stage,chordotonal organ & neuron & embryo,axon & embryonic central nervous system,dendrite | embryonic stage | lateral,multidendritic neuron & dendrite & embryo,chaeta,socket,photoreceptor cell R7 | pupal stage,growth cone | pupal stageGMR.long,photoreceptor cell R8 | pupal stage,photoreceptor cell R8 | adult stage,medulla layer M6 | pupal stage,medulla layer M6 | adult stage,medulla layer M3 | pupal stage,medulla layer M3 | adult stage" FBgn0261560 Thor Thor http://flybase.net/reports/FBgn0261560.html "FBgn0022073, FBgn0017459, FBgn0020516, FBgn0027067, FBgn0046442, FBgn0010616" protein_coding_gene 0008190=eukaryotic initiation factor 4E binding "0045947=negative regulation of translational initiation, 0007525=somatic muscle development, 0006979=response to oxidative stress, 0045792=negative regulation of cell size, 0006641=triglyceride metabolic process, 0001558=regulation of cell growth, 2000331=regulation of terminal button organization, 0019731=antibacterial humoral response, 0042594=response to starvation, 0007520=myoblast fusion, 0070129=regulation of mitochondrial translation, 0006952=defense response, 0008340=determination of adult lifespan, 0009617=response to bacterium, 0006955=immune response" "eukaryotic translation initiation factor 4E binding protein, BcDNA:HL08053, 4e-BP, 4E-BP, 43-BP, Phas1, d4E-BP1, anon-WO0172774.158, insulin-stimulated eIF-4E binding protein, thor, d4EBP, lethal (2) 06270, eukaryotic initiation factor 4E-binding protein, CG8846, translation initiation factor 4E binding protein, 4ebp, d4eBP, 4e-bp, l(2)k07736, dthor, BcDNA.HL08053, CT8705, l(2)06270, 4eBP, Eif4e-binding protein, eukaryotic initiation factor 4E binding protein, eIF4E-BP, pp20, 4E-BP1, d4E-BP, eIF4E binding protein, Thor/EIF4EBP, 153432_at, eukaryotic translation initiation factor 4E-binding protein, 4EBP, eif4e-binding protein 4EBP, l(2)k13517, 4E binding protein, eIF-4E-binding protein, Dm 4E-BP, d4e-bp" IPR008606=Eukaryotic translation initiation factor 4E binding CG8846 16-Dec-15 2015_12 "ENSDARG00000043608(zgc:64137),ENSDARG00000031819(eif4ebp2),ENSDARG00000041607(zgc:56330),ENSDARG00000054916(zgc:103720)" ENSXETG00000025651(Q6P382_XENTR) "ENSMUSG00000020091(Eif4ebp2),ENSMUSG00000031490(Eif4ebp1)" "ENSG00000148730(EIF4EBP2),ENSG00000187840(EIF4EBP1)" " adult stage && oogenesis stage , embryonic stage , embryonic stage -- adult stage , larval stage | third instar " " ovary

, embryonic central nervous system

, nurse cell

, testis

" FBgn0000405 CycB Cyclin B http://flybase.net/reports/FBgn0000405.html protein_coding_gene 0016538=cyclin-dependent protein serine/threonine kinase regulator activity "0000086=G2/M transition of mitotic cell cycle, 0008608=attachment of spindle microtubules to kinetochore, 0000920=cell separation after cytokinesis, 0001700=embryonic development via the syncytial blastoderm, 0035186=syncytial blastoderm mitotic cell cycle, 0007079=mitotic chromosome movement towards spindle pole, 0006974=cellular response to DNA damage stimulus, 0035561=regulation of chromatin binding, 0000281=mitotic cytokinesis" "0019908=nuclear cyclin-dependent protein kinase holoenzyme complex, 0051233=spindle midzone, 0045495=pole plasm, 0000775=chromosome, centromeric region, 0005737=cytoplasm, 0005634=nucleus, 0005819=spindle, 0072686=mitotic spindle" "Cyclin B1, CYC-B, 2g, 3510, mAbF2F4, dCyclinB, cyc-B, cycB, cyclin-B, CYCB, cyc B, CG3510, chr2R:18312808..18312907, cyclin B, Cyc B, Cyclin-B, DmcycB, Cycb, cyclinB, CyclinB" "IPR013763=Cyclin-like, IPR004367=Cyclin, C-terminal domain, IPR006671=Cyclin, N-terminal" CG3510 16-Dec-15 2015_12 "ENSDARG00000051923,ENSDARG00000057930(ccnb1),ENSDARG00000036180(ccnb2)" "WBGene00000865(cyb-1),WBGene00000867(cyb-2.2),WBGene00000866(cyb-2.1)" "ENSXETG00000026059(ccnb2),ENSXETG00000010845(TEgg042m05.1),ENSXETG00000016354(ccnb1),ENSXETG00000000477(XTR303453.1)" "ENSMUSG00000041431(Ccnb1),ENSMUSG00000048574(Gm5593),ENSMUSG00000032218(Ccnb2)" "ENSG00000134057(CCNB1),ENSG00000157456(CCNB2)" " embryonic stage | early , adult stage && oogenesis stage | stage S9,10 , embryonic stage , adult stage && oogenesis stage , adult stage && oogenesis stage | <= stage S7 , larval stage , adult stage | male , embryonic stage | gastrula , adult stage | female " "

posterior{ 0 nos* } , nurse cell

, epidermis

,

posterior{ 0 pum* } , germarium

,

posterior{ - vas* } , oocyte

, pole cell

, embryonic central nervous system

,

posterior{ 0 Bic-D* } ,

posterior{ 0 tud* } ,

posterior{ - capu* } , testis

,

posterior{ - stau* } , organism | posterior

,

posterior{ - spir* } ,

posterior{ 0 vls* } ,

,

posterior{ - osk* } " " embryonic stage , larval stage , embryonic stage | early , embryonic stage | syncytial blastoderm , embryonic stage | stage 13 " " peripheral nervous system

, imaginal disc

{ 0 cycA- } , larval brain

, embryonic central nervous system

, larval central nervous system

, embryonic nervous system

, central nervous system

,

{ 0 cycA- } " "viable,fertile,female sterile,recessive,male sterile,mitotic cell cycle defective,semidominant,meiotic cell cycle defective,wild-type,cytokinesis defective,maternal effect,partially lethal - majority die,some die during embryonic stage,female,lethal - all die before end of embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "cyst cell,onion stage spermatid & nucleus,onion stage spermatid & nuclear chromosome,ovary,larval outer optic anlage,kinetochore,pole cell,cell cycle,anaphase & condensed nuclear chromosome,mitotic anaphase,anaphase & condensed nuclear chromosome | maternal effect,cycle 6 embryo,maternal effect,cycle 7 embryo,cycle 8 embryo,cycle 9 embryo,cycle 10 embryo,cycle 11 embryo,mitotic interphase | maternal effect,mitotic prophase | maternal effect,mitotic metaphase | maternal effect,cycle 14 embryo,aster | embryonic cycle 5,aster | embryonic cycle 6,aster | embryonic cycle 7,energid,mitosis | embryonic stage | maternal effect,microtubule | embryonic cycle 9 | maternal effect,astral microtubule | embryonic cycle 9 | maternal effect,cycle 12 embryo,mitotic interphase | embryonic cycle 10,mitotic interphase | embryonic cycle 11,mitotic interphase | embryonic cycle 12,mitotic interphase | embryonic cycle 13,mitosis | embryonic cycle 10,mitosis | embryonic cycle 11,mitosis | embryonic cycle 12,mitosis | embryonic cycle 13,supernumerary,aster,interphase | maternal effect,female germline cell,embryonic abdominal segment,filzkorper,egg chamber & cell,egg chamber & mitotic cell cycle,spindle | embryonic stagemat.ë±Tub67C.THsimVP16,mitotic cell cycleprd.RG1,mitotic anaphaseprd.RG1,eye,wing,macrochaeta" FBgn0045482 Gr59b Gustatory receptor 59b http://flybase.net/reports/FBgn0045482.html "FBgn0034818, FBgn0045484, FBgn0050191" protein_coding_gene 0008527=taste receptor activity 0050909=sensory perception of taste 0016021=integral component of membrane "GR59b, CG13537, Gr59D3, Gr59C1, Gustatory receptor 59C1, Gustatory receptor 59D3, CG30191, GR59C.2" IPR013604=7TM chemoreceptor CG30191 16-Dec-15 2015_12 FBgn0013556 l(3)ry16 lethal (3) ry16 http://flybase.net/reports/FBgn0013556.html gene l(3)16 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0015609 CadN Cadherin-N http://flybase.net/reports/FBgn0015609.html "FBgn0002007, FBgn0019859" protein_coding_gene "0005509=calcium ion binding, 0045296=cadherin binding, 0004872=receptor activity, 0042803=protein homodimerization activity, 0005515=protein binding, 0008013=beta-catenin binding, 0050839=cell adhesion molecule binding" "0048814=regulation of dendrite morphogenesis, 0007413=axonal fasciculation, 0044331=cell-cell adhesion mediated by cadherin, 0007155=cell adhesion, 0031290=retinal ganglion cell axon guidance, 0045467=R7 cell development, 0045463=R8 cell development, 0007411=axon guidance, 0048841=regulation of axon extension involved in axon guidance, 0048675=axon extension, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0016318=ommatidial rotation, 0048846=axon extension involved in axon guidance, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007412=axon target recognition, 0050774=negative regulation of dendrite morphogenesis" "0005887=integral component of plasma membrane, 0005886=plasma membrane, 0030425=dendrite, 0005911=cell-cell junction, 0030424=axon, 0016021=integral component of membrane" "N-Cad, DN-CAd, cadN, l(2)Bld, DN-Cad, DN-Cadherin, N-Cadh, DN-CADHERIN, Drosophila neuronal cadherin, l(2)36Da, Ncad, ncad, DNCad, lethal(2)36Da, S(DmcycE[JP])2.12, NCAD, B, n-cadherin, CT21941, NCad, n-cad, DN-CAD, DNcad, N-cad, DN-cadherin, DN, CadherinN, D-cad, N-cadherin, N-CADHERIN, DN-cadherin1, DN cadherin, cad1, anon-EST:CL32, DN-cad, N-Cadherin, NCadherin, Cad-N, CG7100" "IPR000742=EGF-like domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000233=Cadherin, cytoplasmic domain, IPR015919=Cadherin-like, IPR002126=Cadherin, IPR001881=EGF-like calcium-binding domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR027397=Catenin binding domain, IPR020894=Cadherin conserved site" CG7100 16-Dec-15 2015_12 WBGene00001980(hmr-1) ENSXETG00000006636() " embryonic stage | stage 5 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage >5 " " mesoderm anlage

, ventral nerve cord

, embryonic neuron

, mesoderm

" " embryonic stage , larval stage | third instar , embryonic stage | stage >=9 " " motor nerve

, neuropil

, neuron

, longitudinal connective

, mesoderm

, myoblast

, anterior commissure

, posterior commissure

, embryonic nervous system

, photoreceptor cell

, adult myoblast

" "neuroanatomy defective,somatic clone,optomotor response defective,viable,courtship behavior defective,male,uncoordinated,locomotor behavior defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die during embryonic stage,sterile,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during larval stage,body size defective,cell polarity defective,visible" "antennal lobe glomerulus DL1,somatic clone,antennal lobe glomerulus DL3,antennal lobe glomerulus VM7,olfactory receptor neuron,medulla,photoreceptor cell R7,cone cell,lamina monopolar neuron,anterior commissure,presumptive embryonic/larval central nervous system,MP1 neuron,dMP2 neuron,MP1 tract,medulla layer M10,medulla layer M5,medulla layer M2,lamina monopolar neuron L5,antennal lobe glomerulus,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,eye photoreceptor cell & axon | somatic clone | cell autonomous,longitudinal connective,vMP2 neuron,antennal lobe glomerulus DA1,medullary intrinsic neuron Mi1,adult brain,photoreceptor cell R8,photoreceptor cell R4,lamina plexus,lateral longitudinal fascicle,medulla layer M6,medulla layer M3,photoreceptor cell,cell non-autonomous,primary pigment cell,ommatidium,ommatidial precursor cluster,eye photoreceptor cell,lamina,optic cartridge,mesothoracic tergum" FBgn0036342 CG11279 http://flybase.net/reports/FBgn0036342.html FBgn0063191 protein_coding_gene BcDNA:GM21080 IPR019034=Uncharacterised protein family UPF0390 CG11279 16-Dec-15 2015_12 "viable,fertile" FBgn0034008 CG8152 http://flybase.net/reports/FBgn0034008.html protein_coding_gene 0003676=nucleic acid binding "IPR000467=G-patch domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG8152 16-Dec-15 2015_12 ENSDARG00000053995(zgc:171777) WBGene00014256(ZK1320.7) ENSXETG00000002509(BAT4) ENSMUSG00000024389(Bat4) "ENSG00000204438(GPANK1),ENSG00000096153,ENSG00000206408" "viable,fertile" FBgn0031001 CG7884 http://flybase.net/reports/FBgn0031001.html protein_coding_gene CG7884 16-Dec-15 2015_12 FBgn0020338 anon-62DEa anon-62DEa http://flybase.net/reports/FBgn0020338.html gene "3C12, unnamed" 16-Dec-15 2015_12 FBgn0032296 CG6729 http://flybase.net/reports/FBgn0032296.html protein_coding_gene "0000184=nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" "IPR028802=Protein SMG8, IPR019354=Smg8/Smg9" CG6729 16-Dec-15 2015_12 ENSDARG00000061378(LOC567424) WBGene00010551(smg-8) ENSXETG00000001117(C17orf71) ENSMUSG00000020495(1200011M11Rik) ENSG00000167447(SMG8) DRSC22793 E -1.272567231 0.036046948 -0.907534642 -1.916433905 0.140404077 -0.877876221 FBgn0266064 GlyS Glycogen synthase http://flybase.net/reports/FBgn0266064.html "FBgn0022803, FBgn0038293, FBgn0062238" protein_coding_gene 0004373=glycogen (starch) synthase activity "0045819=positive regulation of glycogen catabolic process, 0071329=cellular response to sucrose stimulus, 0045772=positive regulation of autophagic vacuole size, 0005977=glycogen metabolic process, 0005978=glycogen biosynthetic process, 0009744=response to sucrose, 1902350=cellular response to chloroquine" "CG6904, glycogen synthase, dGS, GS, CG6940, anon-WO0118547.108" IPR008631=Glycogen synthase CG6904 16-Dec-15 2015_12 "ENSDARG00000004904(gys2),ENSDARG00000016875(gys1)" "YFR015C(GSY1),YLR258W(GSY2)" WBGene00001793(gsy-1) ENSXETG00000021239(GYS1) "ENSMUSG00000003865(Gys1),ENSMUSG00000030244(Gys2)" "ENSG00000104812(GYS1),ENSG00000111713(GYS2)" FBgn0065585 l(2)SH0912 lethal (2) SH0912 http://flybase.net/reports/FBgn0065585.html gene l(2)SH2 0912 16-Dec-15 2015_12 "lethal,recessive" FBgn0000479 dnc dunce http://flybase.net/reports/FBgn0000479.html "FBgn0024972, FBgn0029653, FBgn0029654, FBgn0029655, FBgn0052498" protein_coding_gene "0004115=3',5'-cyclic-AMP phosphodiesterase activity, 0004114=3',5'-cyclic-nucleotide phosphodiesterase activity" "0048477=oogenesis, 0007619=courtship behavior, 0040040=thermosensory behavior, 0019933=cAMP-mediated signaling, 0007623=circadian rhythm, 0007612=learning, 0007613=memory, 0048675=axon extension, 0000003=reproduction, 0001661=conditioned taste aversion, 0045475=locomotor rhythm, 0048149=behavioral response to ethanol, 0046958=nonassociative learning, 0007617=mating behavior, 0007611=learning or memory, 0046331=lateral inhibition, 0010738=regulation of protein kinase A signaling, 0008306=associative learning, 0008355=olfactory learning, 0007268=synaptic transmission, 0009187=cyclic nucleotide metabolic process, 0007614=short-term memory" "CG32498, EG:96G10.7, EG:BACN5I9.2, CG10791, PDE4, CG10797, PDEII, EG:140G11.4, CG14268, EG:BACN05I09.3, CG14267, Dunce, fs(1)M42, dunce, CG10792" "IPR023088=3'5'-cyclic nucleotide phosphodiesterase, IPR003607=HD/PDEase domain, IPR023174=3'5'-cyclic nucleotide phosphodiesterase, conserved site, IPR002073=3'5'-cyclic nucleotide phosphodiesterase, catalytic domain" CG32498 16-Dec-15 2015_12 "ENSDARG00000032761(LOC566998),ENSDARG00000013221(pde4c),ENSDARG00000032868(LOC565706),ENSDARG00000002411(si:ch211-255d18.1),ENSDARG00000032344(LOC572061)" WBGene00020114(pde-4) "ENSXETG00000011637(PDE4A),ENSXETG00000020374(PDE4B),ENSXETG00000012922(PDE4C),ENSXETG00000018854(PDE4D)" "ENSMUSG00000021699(Pde4d),ENSMUSG00000028525(Pde4b),ENSMUSG00000032177(Pde4a),ENSMUSG00000031842(Pde4c)" "ENSG00000113448(PDE4D),ENSG00000184588(PDE4B),ENSG00000065989(PDE4A),ENSG00000105650(PDE4C)" adult stage " mushroom body

, mushroom body

" " adult stage , larval stage | third instar " " neuropil

, calyx of mushroom body

, subesophageal ganglion

, nodulus

, mushroom body

, mushroom body gamma-lobe

, protocerebrum

, lobula

, ellipsoid body

, medulla

, antennal lobe

, fan shaped body

, pedunculus

, lobula plate neuropil

" "viable,fertile,courtship behavior defective,smell perception defective,memory defective,learning defective,semidominant,neuroanatomy defective,neurophysiology defective,chemical sensitive,recessive,behavior defective,optomotor response defective,visual behavior defective,thermotaxis behavior defective,locomotor rhythm defective,partially lethal - majority die,female sterile,female fertile,starvation stress response defective,tarsal response defective,sleep defective,sterile,short lived,female,visible,circadian rhythm defective,some die during pupal stage" "synapse | ectopic,glomerulus,aCC neuron,RP2 motor neuron,neuromuscular junction,larval brain & neuron,mushroom body & neuron,muscle fiber,neuron,adult brain,axon & motor neuron,varicosity | third instar larval stage,neuromuscular junction | third instar larval stage,nurse cell,dorsal appendage,egg chamber,embryonic/larval somatic muscle,nurse cell & nucleusN-64i16),supernumerary,nurse cell & nucleus,synapse,postsynaptic membrane,RP3 neuron & postsynaptic membrane,RP3 neuron & synaptic vesicle,RP3 motor neuron,motor neuron,multidendritic neuron,embryonic/larval neuromuscular junction,growth cone & embryonic neuron,cell body & embryonic neuron,nurse cell & nucleus | germ-line clone,wing,neuromuscular junction | larval stageD42,neuromuscular junction & abdominal 4 ventral longitudinal muscle 4 & larvaD42,neuromuscular junction & abdominal 4 ventral longitudinal muscle 3 & larvaD42,neuromuscular junction & abdominal ventral longitudinal muscle 1 & larvaD42,neuromuscular junction & abdominal ventral longitudinal muscle 2 & larvaD42,neuromuscular junctionD42,dense body,synapseD42,embryonic/larval neuromuscular junction | third instar larval stage,type II bouton | third instar larval stage,mesothoracic tergum,chaeta" DRSC17759 E 0.1639707 -1.39289055 -2.16408386 -0.98813988 1.387327623 0.433385792 FBgn0027066 Eb1 Eb1 http://flybase.net/reports/FBgn0027066.html FBgn0010578 protein_coding_gene "0008017=microtubule binding, 0017022=myosin binding, 0005515=protein binding" "0040001=establishment of mitotic spindle localization, 0030951=establishment or maintenance of microtubule cytoskeleton polarity, 0007626=locomotory behavior, 0007629=flight behavior, 0007423=sensory organ development, 0007017=microtubule-based process, 0000022=mitotic spindle elongation, 0007059=chromosome segregation, 0007605=sensory perception of sound, 0000226=microtubule cytoskeleton organization, 0035011=melanotic encapsulation of foreign target, 0042060=wound healing, 0051225=spindle assembly, 0007052=mitotic spindle organization, 0030589=pseudocleavage involved in syncytial blastoderm formation" "0005875=microtubule associated complex, 0005881=cytoplasmic microtubule, 0005876=spindle microtubule, 0005737=cytoplasm, 0005874=microtubule, 0035371=microtubule plus-end" "DmEB1, dEB1, MT-plus-end-binding protein, EB-1, l(2)04524, anon-EST:Liang-2.33, Dm EB1, anon-EST:Liang-2.52, microtubule plus-tip protein EB1, BcDNA.LD08743, S(DmcycE[JP])2.5, +TIP End-Binding 1, l(2)4524, BcDNA:LD08743, clone 2.33, eb1, dEb1, clone 2.52, EB1, dEB-1, CG3265" "IPR001715=Calponin homology domain, IPR027328=Microtubule-associated protein RP/EB, IPR004953=EB1, C-terminal" CG3265 16-Dec-15 2015_12 "ENSDARG00000012330(zgc:91952),ENSDARG00000059344(LOC100150311),ENSDARG00000020231(zgc:114065),ENSDARG00000002659(mapre1),ENSDARG00000071184,ENSDARG00000042927(mapre1l),ENSDARG00000028771(LOC100331192)" YER016W(BIM1) "WBGene00013344(ebp-1),WBGene00007062(ebp-3)" ENSXETG00000006620(mapre1) "ENSMUSG00000027479(Mapre1),ENSMUSG00000029166(Mapre3)" "ENSG00000101367(MAPRE1),ENSG00000084764(MAPRE3)" larval stage | third instar tendon cell

"partially lethal - majority die,lethal,recessive,neuroanatomy defective,uncoordinated,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,flightless,visible,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,wound healing defective,viable,immune response defective" "S2 cell-line,cytoplasmic microtubule,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,spindle & syncytial blastoderm embryo | maternal effect,nucleus & syncytial blastoderm embryo | maternal effect,macrochaeta,axon,microtubule,Johnston organ,Wheeler's organ,wing,spindle microtubule & astral microtubule,mitotic prophase,mitotic metaphase,mitotic telophase,spindle,epithelial cell,trichogen cell,axonelav.PLu,microtubuleelav.PLu" FBgn0035621 CG10591 http://flybase.net/reports/FBgn0035621.html protein_coding_gene CG10591 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC27468 K 0.56726997 0.09106826 0.019164002 -0.092013076 -0.821289776 -1.607242857 FBgn0002973 numb numb http://flybase.net/reports/FBgn0002973.html "FBgn0010532, FBgn0010684" protein_coding_gene "0003676=nucleic acid binding, 0005112=Notch binding, 0005515=protein binding" "0016360=sensory organ precursor cell fate determination, 0001709=cell fate determination, 0035050=embryonic heart tube development, 0045035=sensory organ precursor cell division, 0008347=glial cell migration, 0051960=regulation of nervous system development, 0008104=protein localization, 0007419=ventral cord development, 0009786=regulation of asymmetric cell division, 0061382=Malpighian tubule tip cell differentiation, 0007400=neuroblast fate determination, 0061320=pericardial nephrocyte differentiation, 0008593=regulation of Notch signaling pathway, 0045807=positive regulation of endocytosis, 0045746=negative regulation of Notch signaling pathway, 0007622=rhythmic behavior, 0007405=neuroblast proliferation, 0042694=muscle cell fate specification, 0007507=heart development, 0007417=central nervous system development, 0007219=Notch signaling pathway, 0055059=asymmetric neuroblast division, 0007422=peripheral nervous system development, 0050767=regulation of neurogenesis, 0008356=asymmetric cell division, 0045165=cell fate commitment, 0051642=centrosome localization" "0005737=cytoplasm, 0005634=nucleus, 0045180=basal cortex, 0005938=cell cortex, 0045178=basal part of cell" "N7-1, numbs, Numb, d-Numb, dNumb, nb, l(2)s2201, CG3779, Nb, l(2)3235, d-numb, l(2)03235" "IPR006020=PTB/PI domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR016698=Numb/numb-like, IPR010449=NUMB domain" CG3779 16-Dec-15 2015_12 "ENSDARG00000024043(numbl),ENSDARG00000027279(numb)" WBGene00003830(num-1) "ENSXETG00000000991(numb),ENSXETG00000002568(NUMBL)" "ENSMUSG00000021224(Numb),ENSMUSG00000063160(Numbl)" "ENSG00000133961(NUMB),ENSG00000105245(NUMBL)" " larval stage--adult stage , embryonic stage | 0-3 hr , embryonic stage | >=3 hr , adult stage | female , oogenesis stage && adult stage | female " ovary

" adult stage , embryonic stage | 3-17 hr , embryonic stage , embryonic stage | 0-5 hr " " external sensory organ precursor cell

, peripheral nervous system | restricted

, neuroblast

, sensory mother cell

, embryonic ganglion mother cell

" "neuroanatomy defective,viable,fertile,visible,lethal,cell death defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,tumorigenic,heat sensitive,somatic clone,some die during immature adult stage,flightless" "abdominal dorsal acute muscle,A1-7 dorsal oblique muscle 1,abdominal dorsal oblique muscle,hypodermal muscle of larval abdominal 9,,scutellar bristle,dMP2 neuron,multidendritic neuron,embryonic/larval pericardial cell,embryonic/larval somatic muscle,neuron,abdominal dorsal bipolar neuron dbp,dorsal multidendritic neuron,cardioblast,glial cell of the perineurium,Malpighian tubule tip cell,segment border muscle,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,EW1 neuron,EW2 neuron,EW3 neuron,abdominal lateral longitudinal muscle,abdominal ventral acute muscle,abdominal lateral transverse muscle,dorsal oblique muscle,dorsal transverse muscle,dorsal acute muscle,abdominal 1 ventral adult muscle precursor cell,abdominal 2 ventral adult muscle precursor cell,abdominal 3 ventral adult muscle precursor cell,abdominal 4 ventral adult muscle precursor cell,abdominal 5 ventral adult muscle precursor cell,abdominal 6 ventral adult muscle precursor cell,abdominal 7 ventral adult muscle precursor cell,abdominal adult muscle precursor cell,abdominal 1 dorsal adult muscle precursor cell,abdominal 2 dorsal adult muscle precursor cell,abdominal 3 dorsal adult muscle precursor cell,abdominal 4 dorsal adult muscle precursor cell,abdominal 5 dorsal adult muscle precursor cell,abdominal 6 dorsal adult muscle precursor cell,abdominal 7 dorsal adult muscle precursor cell,abdominal segment border muscle,pericardial cell,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle,RP2 motor neuron,RP2sib neuron,vMP2 neuron,U neuron,Usib neuron,EL neuron,chordotonal organ,thecogen cell,embryonic somatic muscle,presumptive embryonic/larval peripheral nervous system,abdominal ventral longitudinal muscle,RP3 motor neuron,RP1 motor neuron,A1-7 dorsal acute muscle 1,A1-7 dorsal oblique muscle 2,peripheral glial cell,spermatogonium,trichogen cell,tormogen cell,postorbital bristle,external sensory organ,eo neuron,scolopidial dendritic cap cell,scolopale cell,scolopidial neuron,microchaeta,macrochaeta,dorsal row,ventral row,interommatidial bristle,mechanosensory sensory organ,socket,chaeta,sensory neuron,external sensory organ precursor cell IIa,sense organ,ganglion mother cell GMC4-2a,pCC neuron,aCC neuron,ganglion mother cell GMC1-1a,ganglion mother cell,external sensory organ precursor cell IIb,embryonic heart cardioblast,dorsal abdominal da1,external sensory organ precursor cell I,centrosome,ventral nerve cord,embryonic/larval brain,bract,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,lateral ventral subperineurial glial cell,embryonic Malpighian tubule,embryonic Malpighian tubule tip cell,trichome,wing sensillum,embryonic/larval neuron,wing,adult sense organ,scolopale cell |,abdominal ventral muscle,pericardial cell |,antenna,-P309,notal microchaeta,mesothoracic tergum,larval optic anlage,sensory mother cell,external sensory organ precursor cell IIIb,eo sensory structure" FBgn0044058 GTD74-61-3 GTD74-61-3 http://flybase.net/reports/FBgn0044058.html gene 16-Dec-15 2015_12 viable FBgn0030097 CG12115 http://flybase.net/reports/FBgn0030097.html FBgn0063130 protein_coding_gene BcDNA:LP02922 CG12115 16-Dec-15 2015_12 "partially lethal - majority die,visible" mesothoracic tergum FBgn0002227 l(3)68Ag lethal (3) 68Ag http://flybase.net/reports/FBgn0002227.html gene "l(3)SG20, l(3)68Ag', l(3)ds10, E, l(3)E, l(3)517, Complementation group E" 16-Dec-15 2015_12 "male sterile,visible,recessive,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,imaginal disc" FBgn0002557 longevity longevity http://flybase.net/reports/FBgn0002557.html gene lon 16-Dec-15 2015_12 "paralytic,recessive,lethal,some die during immature adult stage" FBgn0062703 EP1081 EP1081 http://flybase.net/reports/FBgn0062703.html gene EP(2)1081 16-Dec-15 2015_12 FBgn0005007 dimorphos dimorphos http://flybase.net/reports/FBgn0005007.html gene "di, dm, dimorphos" 16-Dec-15 2015_12 "wing,eye" FBgn0000499 dsh dishevelled http://flybase.net/reports/FBgn0000499.html "FBgn0027244, FBgn0042225" protein_coding_gene "0070300=phosphatidic acid binding, 0019904=protein domain specific binding, 0005112=Notch binding" "0048076=regulation of compound eye pigmentation, 0007507=heart development, 0060914=heart formation, 0035159=regulation of tube length, open tracheal system, 0007394=dorsal closure, elongation of leading edge cells, 0016055=Wnt signaling pathway, 0045198=establishment of epithelial cell apical/basal polarity, 0045773=positive regulation of axon extension, 0007391=dorsal closure, 0030707=ovarian follicle cell development, 0007464=R3/R4 cell fate commitment, 0032231=regulation of actin filament bundle assembly, 0007163=establishment or maintenance of cell polarity, 0007298=border follicle cell migration, 0016318=ommatidial rotation, 0007476=imaginal disc-derived wing morphogenesis, 0007411=axon guidance, 0031290=retinal ganglion cell axon guidance, 0035019=somatic stem cell maintenance, 0016477=cell migration, 0060071=Wnt signaling pathway, planar cell polarity pathway, 0048730=epidermis morphogenesis, 0046847=filopodium assembly, 0003136=negative regulation of heart induction by canonical Wnt signaling pathway, 0030032=lamellipodium assembly, 0035317=imaginal disc-derived wing hair organization, 0008585=female gonad development, 0007423=sensory organ development, 0048106=establishment of thoracic bristle planar orientation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity, 0048477=oogenesis, 0016348=imaginal disc-derived leg joint morphogenesis, 0007435=salivary gland morphogenesis, 0016201=synaptic target inhibition, 0035556=intracellular signal transduction, 0007164=establishment of tissue polarity, 1902669=positive regulation of axon guidance, 0001745=compound eye morphogenesis, 0008104=protein localization, 0090163=establishment of epithelial cell planar polarity, 0035309=wing and notum subfield formation, 0008045=motor neuron axon guidance, 0042067=establishment of ommatidial planar polarity, 0048675=axon extension, 0045746=negative regulation of Notch signaling pathway" "0005737=cytoplasm, 0005886=plasma membrane, 0005938=cell cortex, 0005912=adherens junction" "disshevelled, Dsh, l(1)dsh, l(1)G0267, l(1)G17, Dvl, Dm Dsh, disheveled, Disheveled, Dishevelled, CG18361, CG1720, l(1)10Bd, DSH" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR003351=Dishevelled protein domain, IPR015506=Dishevelled-related protein, IPR029071=Ubiquitin-related domain, IPR008339=Dishevelled family, IPR001158=DIX domain, IPR001478=PDZ domain, IPR026542=Dishevelled Dsh, IPR000591=DEP domain" CG18361 16-Dec-15 2015_12 "ENSDARG00000002148(LOC100149082),ENSDARG00000015707(dvl3),ENSDARG00000056184(dvl2),ENSDARG00000055552(dvl2l),ENSDARG00000010515(si:dkey-223i19.4)" WBGene00001101(dsh-1) "ENSXETG00000011120(DVL1),ENSXETG00000017275(DVL3),ENSXETG00000017212(DVL2)" "ENSMUSG00000003233(Dvl3),ENSMUSG00000020888(Dvl2),ENSMUSG00000029071(Dvl1)" "ENSG00000161202(DVL3),ENSG00000004975(DVL2),ENSG00000107404(DVL1)" " embryonic stage -- adult stage , adult stage && oogenesis stage , larval stage , embryonic stage | stage 11 , embryonic stage | early , embryonic stage " " egg chamber

, imaginal disc

,

ubiquitous " "lethal,some die during pupal stage,partially lethal - majority die,visible,lethal - all die before end of pupal stage,viable,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,planar polarity defective,heat sensitive,cell polarity defective,dominant,wild-type,lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,cell death defective,somatic clone,fertile,cell autonomous,partially lethal - majority live,female sterile,male,male fertile,cell non-autonomous,germline clone,segment polarity phenotype" "filzkorper,eye,wing vein,eye photoreceptor cell,ommatidium,denticle belt,embryonic/first instar larval cuticle,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,germline clone,follicle cell,somatic clone,microchaeta,supernumerary,heat sensitive,macrochaeta & wing,sensory mother cell,wing hair,adult,wing,antenna,scutum,pronotum,photoreceptor cell R4,cephalopharyngeal skeleton,adult thorax,dorsal,primordium of embryonic/larval spiracle,posterior,fronto-orbital plate,frons,leg,dorsal cluster neuron,medulla,axon & dorsal cluster neuron,follicle stem cell,lamina,neuron,ovary,germarium,egg chamber,ovarian sheath,triple row,tarsal segment 1 & joint,tarsal segment 2 & joint,tarsal segment 3,tarsal segment 4,embryonic/larval dorsal vessel,wing hinge,axillary pouch,yellow club,pleural wing process,pleural wing sclerite,precursor,macrochaeta,embryonic epidermis,wing sensillum,ectopic,chaeta,trichome,leg & joint,joint,mesothoracic tergum & trichome,external sensory organ precursor cell I,cell autonomous,prothoracic femoral bract,prothoracic tibial bract,mesothoracic femoral bract,mesothoracic tibial bract,metathoracic femoral bract,metathoracic tibial bract,interommatidial bristle,adult thorax & microchaeta,embryonic/larval dorsal trunk,dorsal wing blade,anterior,border follicle cell,class IV dendritic arborizing neuron,cell non-autonomous,wing margin bristle,stomodeal invagination,embryonic/larval tracheal system,wing & macrochaeta,photoreceptor cell,eye disc,maternal effect,embryonic dorsal epidermis,embryonic leading edge cell,ventral,wing & triple row | somatic clone,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 8 ventral denticle belt,embryonic head,midgut constriction 2,embryonic leading edge cell & filopodium,embryonic leading edge cell & actin filament,embryonic leading edge cell & microtubule,amnioserosa,ocellus,adult cuticle,adult head,dorsal margin photoreceptor,medial triple row,pigment cell,ventral thoracic disc,secondary pigment cell,tertiary pigment cell,denticle,embryonic ventral epidermis,embryo,presumptive embryonic salivary gland,interfollicle cell,macrochaeta & scutellumptc-559.1,microchaeta & scutellumptc-559.1,wing hair & 1st posterior cellptc-559.1,microchaeta & scutumrho-rhl,morphogenetic furrow,sensory mother cell & dorsal mesothoracic disc | ectopicsd-SG29.1,wing disc,dorsal cluster neuron | adult stage,medulla | adult stage" FBgn0001122 Gë±o G protein ë± o subunit http://flybase.net/reports/FBgn0001122.html FBgn0026838 protein_coding_gene "0004871=signal transducer activity, 0005525=GTP binding, 0031683=G-protein beta/gamma-subunit complex binding, 0005515=protein binding, 0003924=GTPase activity, 0001664=G-protein coupled receptor binding" "0007186=G-protein coupled receptor signaling pathway, 0042595=behavioral response to starvation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway, 0019991=septate junction assembly, 0050916=sensory perception of sweet taste, 0007507=heart development, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0030866=cortical actin cytoskeleton organization, 0061343=cell adhesion involved in heart morphogenesis, 0060857=establishment of glial blood-brain barrier, 0007419=ventral cord development, 0008356=asymmetric cell division, 0019722=calcium-mediated signaling, 0016055=Wnt signaling pathway" "0031234=extrinsic component of cytoplasmic side of plasma membrane, 0005886=plasma membrane, 0005834=heterotrimeric G-protein complex" "bkh, Galpha[[0]], G-oalpha, Goalpha, G[[oalpha]], Drogpad, brokenhearted, Goalpha47a, G-oalpha47A, CG2204, Galpha[[047A]], Galpha[[o]]47A, G[[o]]alpha, brokenheart, DROGPAD, Bkh, G(o)alpha47A, Goa, DGalpha[[o]], goalpha, G[[o]], dgoalpha, Galpha[[o]], Go-alpha, G-alpha-47A, Galphao, G-oalpha47a, drogpad, Go, dgo, alpha(o), G protein oalpha 47A, DG[[o]], DGalpha0, Galphao47A, Galpha47A" "IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025=G protein alpha subunit, helical insertion, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001408=G-protein alpha subunit, group I" CG2204 16-Dec-15 2015_12 "ENSDARG00000016676(gnao1a),ENSDARG00000036058(gnao1b)" YHR005C(GPA1) WBGene00001648(goa-1) ENSXETG00000020022(gnao1) ENSMUSG00000031748(Gnao1) ENSG00000087258(GNAO1) " embryonic stage--pupal stage , embryonic stage | 0-2 hr , adult stage && oogenesis stage " " nurse cell

, oocyte

" " adult stage , embryonic stage | stage >=13 " " adult antennal nerve | restricted

, neuropil adult brain

, neuropil

, lamina | restricted

, adult brain cortex

, neuropil thoracic ganglion

, ocellar nerve | proximal

" "neurophysiology defective,taste perception defective,lethal,recessive,cell polarity defective,somatic clone,planar polarity defective,visible,cell non-autonomous,dominant,neuroanatomy defective,starvation stress response defective,wild-type,viable,circadian rhythm defective,mitotic cell cycle defective,heat sensitive,partially lethal - majority die,cell autonomous" "large labellar taste bristle,embryonic/larval visceral muscle,longitudinal connective,motor neuron,embryonic/larval dorsal vessel,wing,somatic clone,macrochaeta,socket,eo neuron,eo sensory structure,sensory organ cell,ectopic,wing margin,wing hair,supernumerary,wing margin bristle,cell non-autonomous,denticle belt,embryonic/first instar larval cuticle,neuroblast,embryonic/larval neuromuscular junction | third instar larval stage,type II bouton,supernumerary | third instar larval stage,type I bouton,medial triple row & socketpnr-MD237,medial triple row & eo neuronpnr-MD237,medial triple row & eo sensory structurepnr-MD237,medial triple row & sensory organ cellpnr-MD237,neuroblast & spindlemat.ë±Tub67C.THsimVP16,heat sensitive,cell autonomous,mechanosensory sensory organ,medial triple row,sensory mother cell,thecogen cell,eo glial cell,scolopidial neuron,nervous system" FBgn0000250 cact cactus http://flybase.net/reports/FBgn0000250.html FBgn0013453 protein_coding_gene "0008134=transcription factor binding, 0005515=protein binding" "0006967=positive regulation of antifungal peptide biosynthetic process, 0007399=nervous system development, 0046843=dorsal appendage formation, 0042308=negative regulation of protein import into nucleus, 0030097=hemopoiesis, 0008063=Toll signaling pathway, 0009950=dorsal/ventral axis specification, 0019732=antifungal humoral response, 0006974=cellular response to DNA damage stimulus, 0019730=antimicrobial humoral response, 0042994=cytoplasmic sequestering of transcription factor, 0006909=phagocytosis, 0009620=response to fungus, 0045087=innate immune response, 0006955=immune response, 0048477=oogenesis, 0006952=defense response" "0005737=cytoplasm, 0031594=neuromuscular junction" "NFkappabeta1A, cac, Cactus, Ikappa, n(2)k17003, CG5848, CACT, Cact, NF-kappa-B inhibitor cactus, dip6, BG:DS02740.15, 5848, fs(2)ltoRN48, female-sterile-(2)-ltoRN48" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG5848 16-Dec-15 2015_12 "ENSDARG00000005481(nfkbiaa),ENSDARG00000007693(nfkbiab)" YIL112W(HOS4) WBGene00007877(C33A11.1) ENSXETG00000017950(nfkbia) ENSMUSG00000021025(Nfkbia) ENSG00000100906(NFKBIA) " embryonic stage | early , adult stage | female , embryonic stage " embryonic stage | early

dorsal ventral gradient "wild-type,lethal,recessive,heat sensitive,visible,maternal effect,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,germline clone,non-rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,viable" "embryonic dorsal epidermis,heat sensitive,wing,wing vein,ectopic,embryonic epidermis,maternal effect,embryonic ventral epidermis,embryonic/first instar larval cuticle,ventral,denticle belt,filzkorper,embryo,dorsal,melanotic mass,embryonic/larval digestive system,lamellocyte,germline clone,hemocyte,embryonic/larval hemolymph,embryonic/larval lymph gland,embryonic/larval spiracle,gastrula embryo,cephalic furrow,amnioserosa,amnioproctodeal invagination,dorsal fold,extended germ band embryo,embryonic leading edge cell,embryonic/larval hemocyte,podocyte,dorsal appendage" DRSC03501 IE -1.50180946 -2.446172305 -0.725100161 -1.852532621 0.217396329 0.288300518 FBgn0051569 tRNA:CR31569 transfer RNA:CR31569 http://flybase.net/reports/FBgn0051569.html "FBgn0004265, FBgn0060279" tRNA_gene "0030533=triplet codon-amino acid adaptor activity, 0033453=GCU codon-amino acid adaptor activity" 0006412=translation 0005829=cytosol "AE002708.trna46-AlaAGC, tRNA:-?:90Cd, CR31569, tRNA[[Ala]], chr3R.trna52-AlaAGC, tRNA:A:AGC:AE002708-j, transfer RNA:?:90Cd" CR31569 16-Dec-15 2015_12 FBgn0001214 Hpb Hydroxyphenyl buten 1 http://flybase.net/reports/FBgn0001214.html gene 0042048=olfactory behavior "Hydroxyphenyl-buten-1, HPB" 16-Dec-15 2015_12 smell perception defective FBgn0032388 CG6686 http://flybase.net/reports/FBgn0032388.html protein_coding_gene 0044822=poly(A) RNA binding "0046579=positive regulation of Ras protein signal transduction, 0070374=positive regulation of ERK1 and ERK2 cascade, 0000398=mRNA splicing, via spliceosome, 0022008=neurogenesis" 0071011=precatalytic spliceosome SART1 IPR005011=SNU66/SART1 family CG6686 16-Dec-15 2015_12 ENSDARG00000005945(sart1) YOR308C(SNU66) WBGene00017605(F19F10.9) ENSXETG00000011429(SART1) ENSMUSG00000039148(Sart1) ENSG00000175467(SART1) "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC02979 IE -0.47538527 3.598489137 0.494886636 2.224215305 -1.173148079 -1.233302986 FBgn0025724 ë_'COP Coat Protein (coatomer) ë_' http://flybase.net/reports/FBgn0025724.html protein_coding_gene "0005215=transporter activity, 0005198=structural molecule activity" "0010883=regulation of lipid storage, 0006890=retrograde vesicle-mediated transport, Golgi to ER, 0006886=intracellular protein transport" "0005795=Golgi stack, 0030126=COPI vesicle coat" "beta'Cop, beta'-coatomer protein, CG6699, beta'COP, dbeta'COP, COPI beta' subunit, COPIbeta', beta'-COP" "IPR006692=Coatomer, WD associated region, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR016453=Coatomer beta' subunit (COPB2), IPR020472=G-protein beta WD-40 repeat, IPR017986=WD40-repeat-containing domain" CG6699 16-Dec-15 2015_12 ENSDARG00000038743(copb2) YGL137W(SEC27) WBGene00009542(F38E11.5) ENSXETG00000008250(copb2) ENSMUSG00000032458(Copb2) ENSG00000184432(COPB2) "visible,viable" wing DRSC03492 IE -0.543055187 2.201882846 5.489816522 -3.135324545 -0.290984702 -0.720156747 FBgn0261602 RpL8 Ribosomal protein L8 http://flybase.net/reports/FBgn0261602.html "FBgn0024939, FBgn0027679, FBgn0035352, FBgn0069397, FBgn0002611" protein_coding_gene 0003735=structural constituent of ribosome "0048749=compound eye development, 0007052=mitotic spindle organization, 0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0008286=insulin receptor signaling pathway, 0006412=translation, 0008361=regulation of cell size" "0000228=nuclear chromosome, 0005840=ribosome, 0005730=nucleolus, 0022625=cytosolic large ribosomal subunit, 0005737=cytoplasm" "M(3)62F, Rp L8, RPL8, anon-EST:Posey5, L8, Minute(3)62F, rpL8, CG1263, M(3)LS2" "IPR022666=Ribosomal Proteins L2, RNA binding domain, IPR002171=Ribosomal protein L2, IPR014722=Ribosomal protein L2 domain 2, IPR012340=Nucleic acid-binding, OB-fold, IPR014726=Ribosomal protein L2, domain 3, IPR008991=Translation protein SH3-like domain, IPR022671=Ribosomal protein L2, conserved site, IPR022669=Ribosomal protein L2, C-terminal" CG1263 16-Dec-15 2015_12 ENSDARG00000014867(rpl8) "YIL018W(RPL2B),YFR031C-A(RPL2A)" WBGene00004413(rpl-2) ENSXETG00000015483(rpl8) ENSMUSG00000003970(Rpl8) ENSG00000161016(RPL8) " pupal stage , larval stage | third instar , adult stage | female , embryonic stage , adult stage | male " " embryonic/larval salivary gland

, ovary

, embryonic/larval fat body

" DRSC08695 EK -1.158285147 -0.863536354 -3.750090768 -4.55747933 0.497518724 3.633095475 FBgn0002524 lace lace http://flybase.net/reports/FBgn0002524.html "FBgn0025294, FBgn0027869" protein_coding_gene "0030170=pyridoxal phosphate binding, 0004758=serine C-palmitoyltransferase activity" "0040008=regulation of growth, 0007444=imaginal disc development, 0030111=regulation of Wnt signaling pathway, 1903827=regulation of cellular protein localization, 0008593=regulation of Notch signaling pathway, 0030148=sphingolipid biosynthetic process" "0012505=endomembrane system, 0005886=plasma membrane" "sphingosine palmitoyl transferase, br36, anon-EST:Posey289, l(2)br36, l(2)35Dc, l35Dc, Serine palmitoyltransferase subunit II, CG4162, SPT-II, BG:DS01845.3, Lace" "IPR001917=Aminotransferase, class-II, pyridoxal-phosphate binding site, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR004839=Aminotransferase, class I/classII" CG4162 16-Dec-15 2015_12 ENSDARG00000018976(sptlc2) YDR062W(LCB2) WBGene00018398(sptl-2) "ENSXETG00000011085(SPTLC2),ENSXETG00000008083(SPTLC3)" "ENSMUSG00000021036(Sptlc2),ENSMUSG00000039092(Sptlc3)" "ENSG00000100596(SPTLC2),ENSG00000172296(SPTLC3)" " embryonic stage , larval stage " "

ubiquitous , dorsal mesothoracic disc | ubiquitous

, sensory organ cell &&of embryonic head

, embryonic/larval midgut

, eye-antennal disc | ubiquitous

" "lethal,recessive,visible,developmental rate defective,lethal - all die before end of larval stage,nutrition conditional,some die during third instar larval stage,flight defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "wing,chaeta,eye,ommatidium,crossvein,ectopic,microchaeta,macrochaeta,leg,antenna,wing disc,eye-antennal disc,ventral thoracic disc,cone cell,primary pigment cell,secondary pigment cell,tertiary pigment cell,interommatidial bristle,embryonic head" DRSC03564 I 0.267362789 1.958663635 1.444810526 -0.844704537 0.200037154 0.942181366 FBgn0001624 dlg1 discs large 1 http://flybase.net/reports/FBgn0001624.html "FBgn0010108, FBgn0027239, FBgn0027662, FBgn0028321, FBgn0029052, FBgn0030295, FBgn0066811, FBgn0066812, FBgn0066813" protein_coding_gene "0004385=guanylate kinase activity, 0005515=protein binding, 0005154=epidermal growth factor receptor binding, 0005198=structural molecule activity" "0045196=establishment or maintenance of neuroblast polarity, 0008283=cell proliferation, 0002009=morphogenesis of an epithelium, 0019991=septate junction assembly, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0016334=establishment or maintenance of polarity of follicular epithelium, 0008105=asymmetric protein localization, 0016333=morphogenesis of follicular epithelium, 0042127=regulation of cell proliferation, 0051294=establishment of spindle orientation, 0045475=locomotor rhythm, 0007391=dorsal closure, 0008104=protein localization, 0051726=regulation of cell cycle, 0007010=cytoskeleton organization, 0007268=synaptic transmission, 0007399=nervous system development, 0016335=morphogenesis of larval imaginal disc epithelium, 0045175=basal protein localization, 0000132=establishment of mitotic spindle orientation, 0001738=morphogenesis of a polarized epithelium, 0008049=male courtship behavior, 0007617=mating behavior, 0042332=gravitaxis, 0008285=negative regulation of cell proliferation, 0045167=asymmetric protein localization involved in cell fate determination, 0051124=synaptic growth at neuromuscular junction, 0016336=establishment or maintenance of polarity of larval imaginal disc epithelium, 0046956=positive phototaxis, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0030710=regulation of border follicle cell delamination" "0016020=membrane, 0005886=plasma membrane, 0005938=cell cortex, 0061174=type I terminal bouton, 0045202=synapse, 0031594=neuromuscular junction, 0048471=perinuclear region of cytoplasm, 0016327=apicolateral plasma membrane, 0016323=basolateral plasma membrane, 0005920=smooth septate junction, 0042734=presynaptic membrane, 0005856=cytoskeleton, 0005918=septate junction, 0045211=postsynaptic membrane, 0043195=terminal bouton, 0045179=apical cortex, 0016328=lateral plasma membrane, 0061176=type Ib terminal bouton" "l(1)dlg1, l(1)G19, lethal(1)discs large, anon-EST:Posey93, dlgA, dlg, l(1)dlg, Discs Large, l(1)L11, lethal(2)discs large, Discs large, Disc-large, anon-WO03040301.268, Disc-Large, Dlg-A, anon-WO03040301.260, l(1)10Bf, Discs-Large, DlgA, discs large, CG1730, lethal(1)discs-large, Discs-large, Drodlg, SAP97, l(1)G0342, l(1)d.lg-1, Dlg, Dlg1, PSD95, Disk Large, l(1)G0456, 11, dlg-A, dlgS97, disc large, l(1)dlg-1, Disc large, d. lg.-1, CPD, Discslarge, l(1)l.pr.-2, disc-large, Disc Large, l(1)lpr-2, DlgS97, CG1725, misb, l(1)bwn, discs-large, l(1)discs large, l(1)G0276, discslarge, DLG, DLG-A, l(1)d.lg.-1, dlg-1, disclarge, Discs large 1, DLG1, lethal(1)benign wing imaginal disc neoplasm, anon-WO03040301.258" "IPR008144=Guanylate kinase-like domain, IPR004172=L27 domain, IPR016313=Disks large 1, IPR020590=Guanylate kinase, conserved site, IPR001452=SH3 domain, IPR001478=PDZ domain, IPR015143=L27-1, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG1725 16-Dec-15 2015_12 "ENSDARG00000005133,ENSDARG00000056370,ENSDARG00000029925(dlg1l),ENSDARG00000009677(dlg1),ENSDARG00000012203(dlg3)" WBGene00001006(dlg-1) ENSXETG00000003464(dlg1) "ENSMUSG00000022770(Dlg1),ENSMUSG00000052572(Dlg2),ENSMUSG00000000881(Dlg3),ENSMUSG00000020886(Dlg4)" "ENSG00000075711(DLG1),ENSG00000150672(DLG2),ENSG00000082458(DLG3),ENSG00000132535(DLG4)" " larval stage , adult stage | male , spermatogenesis && adult stage , embryonic stage , adult stage && oogenesis stage , oogenesis stage && adult stage | female " " embryonic/larval proventriculus

, male accessory gland

, primary gonial cell

, testis

, ventral nerve cord

, embryonic/larval digestive system

, peripheral nervous system

, optic lobe

, nurse cell

, larval brain

, oogonial cell

, follicle cell

, epidermis

, embryonic brain

, ejaculatory bulb

, embryonic/larval salivary gland

, imaginal disc

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,somatic clone,viable,neurophysiology defective,some die during third instar larval stage,phototaxis defective,locomotor rhythm defective,courtship behavior defective,mating defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,neuroanatomy defective,hyperplasia,lethal - all die before end of P-stage,some die during pharate adult stage,polyphasic,tumorigenic,flightless,cell polarity defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially lethal - majority die,flight defective,locomotor behavior defective" "embryo,germline clone,eye,somatic clone,eye disc,wing,wing margin,imaginal disc,embryonic/larval brain,presynaptic membrane & neuromuscular junction | larval stage,border follicle cell,follicle cell,heat sensitive,postsynaptic membrane,wing disc,ring gland,bouton,external sensory organ precursor cell I,macrochaeta,interommatidial bristle,antenna,leg,embryonic/larval optic lobe,prothoracic leg disc,mesothoracic leg disc,neuromuscular junction,neuromuscular junction & bouton,neuromuscular junction & postsynaptic membrane,NMJ bouton,subsynaptic reticulum,ventral nerve cord,neuromuscular junction | larval stage,postsynaptic membrane & neuromuscular junction | larval stage,adherens junction,socket,brain,type I bouton & synaptic vesicle & third instar larvaN71),synapse | third instar larval stageN71),imaginal disc & septate junction,adherens junction | ectopic,septate junction,pleated septate junction,cell autonomous,egg chamber,imaginal disc & epithelial cell & plasma membrane | somatic clone,imaginal disc & epithelial cell & septate junction | somatic clone,epithelial cell,neuroblast,embryonic epidermis,presumptive embryonic/larval nervous system,germline cell,embryonic neuroblast,embryonic/first instar larval cuticle,eye-antennal disc,subsynaptic reticulum | third instar larval stage,puparium,prepupal cuticle,dorsal,maternal effect,postsynaptic membraneBG487,subsynaptic reticulumBG487,subsynaptic reticulumMhc.PW" FBgn0035481 CG12605 http://flybase.net/reports/FBgn0035481.html FBgn0044532 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" 0000122=negative regulation of transcription from RNA polymerase II promoter 0005634=nucleus anon-WO0140519.93 "IPR015880=Zinc finger, C2H2-like, IPR029794=Transcriptional repressor SCRATCH 1/2, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG12605 16-Dec-15 2015_12 WBGene00022592(ZC328.2) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" DRSC08286 I 0.579470683 1.792496216 0.72158708 -0.337274373 1.139316112 0.733306549 FBgn0002543 robo2 roundabout 2 http://flybase.net/reports/FBgn0002543.html "FBgn0024195, FBgn0025977, FBgn0031338, FBgn0031339, FBgn0031340, FBgn0031341" protein_coding_gene "0042803=protein homodimerization activity, 0004872=receptor activity, 0008046=axon guidance receptor activity" "0008406=gonad development, 0035050=embryonic heart tube development, 0007419=ventral cord development, 0003151=outflow tract morphogenesis, 0048036=central complex development, 0042685=cardioblast cell fate specification, 0007411=axon guidance, 0022409=positive regulation of cell-cell adhesion, 0007426=tracheal outgrowth, open tracheal system, 0001764=neuron migration, 0016319=mushroom body development, 0007432=salivary gland boundary specification, 2000274=regulation of epithelial cell migration, open tracheal system, 0008039=synaptic target recognition" "0030424=axon, 0005886=plasma membrane" "D-robo2, CT17326, robo-2, Robo2, CG5574, dRobo-2, lea, Robo-2, Leak, roundabout 2, Roundabout 2, Robo 2, Roundabout2, CG14348, ROBO2, Robo2 (Lea), SGP cluster fusion defects 4, D-Robo2, leak, CG5481, roundabout2, fus4, robo2, clone 1.75, CG14347, anon-EST:Liang-1.75" "IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set" CG5481 16-Dec-15 2015_12 " embryonic stage | stage 14 , embryonic stage | stage 13-14 , embryonic stage | stage 13 " " embryonic dorsal trunk && embryonic transverse connective && embryonic dorsal branch && embryonic spiracular branch && embryonic ganglionic branch

, epidermis | dorsal & vicinity of segment boundary

, embryonic dorsal trunk && embryonic transverse connective && embryonic dorsal branch

" "neuroanatomy defective,male,lethal,partially lethal - majority die,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neurophysiology defective,viable,fertile" "gustatory receptor neuron,male,prothoracic leg taste bristle chemosensory neuron,heart primordium,serotonin neuron & ventral nerve cordeg-Mz360,cell body & serotonin neuroneg-Mz360,intersegmental nerve,abdominal lateral pentascolopidial chordotonal organ lch5,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial dendrite,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial dendritic cap cell,ventral nerve cord commissure,antennal commissure,antennal lobe glomerulus,dMP2 neuron,vMP2 neuron,gonad,gonadal sheath proper primordium,commissure,embryonic/larval neuron,ganglionic branch primordium,longitudinal connective,tract,ectopic | embryonic stage,hypostomal sclerite,cephalopharyngeal skeleton,embryonic somatic muscle,lateral process,intermediate longitudinal fascicle,lateral longitudinal fascicle,germline cell,dorsal branch primordium,interface glial cell,fascicle,cardioblast,lch5 neuron,presumptive embryonic/larval central nervous system,ventral nerve cord,motor neuron,ellipsoid body,fan-shaped body,adult mushroom body,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,head,ventral,presumptive embryonic salivary gland,olfactory neuron & antennal lobe | somatic clone,antennal lobe glomerulus DM2,somatic clone,ectopic,embryonic head,serotonin neuron & ventral nerve cord,cell body & serotonin neuron,embryonic pericardial cell,mesothoracic dorsal triscolopidial chordotonal organ dch3,metathoracic dorsal triscolopidial chordotonal organ dch3,giant fiber neuron,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,medial longitudinal fascicle,dorsal branch | third instar larval stage" FBgn0015218 eIF-4E Eukaryotic initiation factor 4E http://flybase.net/reports/FBgn0015218.html "FBgn0002202, FBgn0010921, FBgn0013947, FBgn0028178, FBgn0035984, FBgn0060598, FBgn0060792, FBgn0061015" protein_coding_gene "0003743=translation initiation factor activity, 0031370=eukaryotic initiation factor 4G binding, 0000340=RNA 7-methylguanosine cap binding, 0000339=RNA cap binding, 0005515=protein binding" "0007112=male meiosis cytokinesis, 0030307=positive regulation of cell growth, 0001558=regulation of cell growth, 0048102=autophagic cell death, 0000022=mitotic spindle elongation, 0007060=male meiosis chromosome segregation, 0035071=salivary gland cell autophagic cell death, 0045995=regulation of embryonic development, 0006413=translational initiation, 0002191=cap-dependent translational initiation, 0006325=chromatin organization, 0010032=meiotic chromosome condensation, 0006412=translation, 0048515=spermatid differentiation, 0007076=mitotic chromosome condensation, 0022008=neurogenesis, 0048137=spermatocyte division, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0016070=RNA metabolic process, 0048136=male germ-line cyst formation, 0016321=female meiosis chromosome segregation" "0000932=cytoplasmic mRNA processing body, 0005845=mRNA cap binding complex, 0005737=cytoplasm, 0005829=cytosol, 0016281=eukaryotic translation initiation factor 4F complex, 0097482=muscle cell postsynaptic density, 0031594=neuromuscular junction, 0005875=microtubule associated complex" "eukaryotic translation initiation factor 4E, eIF-4E1,2, 0260/09, l(3)S026009, EIF4E, eIF-4E1, eIF4E, eif4e, 1004/13, eIF4E-1/2, Eif4e, eIF4E-1,2, eukaryotic initiation factor 4E, 0919/12, elF4E, eIF4E-2, CG4035, 7238, eIF-4E2, IF4E, 0589/11, eIF 4E, eIF-4EII, Eukaryotic translation initiation factor 4E, l(3)S025007, eif-4E, deIF-4E, cap binding protein, eif-4e, deIF4E, eIF4e, l(3)S091912, CBP, l(3)07238, CT39426, dEif4e, CT39424, eIF4E-1, 0587/11, D-eIF4E, Eif4E, lethal(3)67Af, l(3)67Af, l(3)S058711, eIF4EI, CT13384, eIF-4e, eIF4E1" "IPR023398=Translation Initiation factor eIF- 4e-like, IPR001040=Translation Initiation factor eIF- 4e, IPR019770=Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG4035 16-Dec-15 2015_12 "ENSDARG00000013274(zgc:101581),ENSDARG00000012274(zgc:110154),ENSDARG00000014565(eif4e1b)" YOL139C(CDC33) WBGene00002061(ife-3) "ENSXETG00000009316(eif4e),ENSXETG00000019631(EIF4E1B)" ENSMUSG00000028156(Eif4e) "ENSG00000151247(EIF4E),ENSG00000175766(EIF4E1B)" " embryonic stage , embryonic stage -- adult stage " " embryonic/larval salivary gland

, embryonic/larval somatic muscle

, pole cell

, embryonic/larval digestive system

, posterior midgut proper primordium

, anterior midgut proper primordium

,

ubiquitous " "viable,lethal,recessive,developmental rate defective,reduced,visible,lethal - all die before end of larval stage,some die during larval stage,decreased cell size,increased cell size,meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,some die during third instar larval stage,wild-type,female sterile,germline clone,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,neuroanatomy defective,chemical sensitive,male,partially lethal - majority die,female,lethal - all die before end of pupal stage,some die during pupal stage" "wing,intersegmental nerve,wing disc,ommatidium,mitosis & nuclear chromosome,mitotic interphase,ventral furrow,embryonic/first instar larval cuticle,eye,interommatidial bristle,ectopic,neuromuscular junctionMhc.PW,bouton,type I bouton,embryonic/larval neuromuscular junction,dopaminergic neuron,embryonic/larval neuroblast,ganglion mother cell" DRSC11342 IEK -1.504138538 -0.970498401 -6.318141051 -2.31893895 -1.643970291 -1.296136804 FBgn0003334 Scm Sex comb on midleg http://flybase.net/reports/FBgn0003334.html protein_coding_gene "0042802=identical protein binding, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0008270=zinc ion binding" "0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0007409=axonogenesis, 0030708=germarium-derived female germ-line cyst encapsulation, 0030713=ovarian follicle cell stalk formation, 0016458=gene silencing, 0045926=negative regulation of growth" "0005700=polytene chromosome, 0035102=PRC1 complex, 0005634=nucleus" "l(3)85Ef, Sex combs on midleg, scm, Sex combs on midlegs, Su(z)302, Sex Comb on Midleg, sex comb on midleg, SCM, CG9495" "IPR012313=Zinc finger, FCS-type, IPR004092=Mbt repeat, IPR021987=Protein of unknown function DUF3588, IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR010507=Zinc finger, MYM-type" CG9495 16-Dec-15 2015_12 ENSXETG00000012966(scmh1) ENSMUSG00000000085(Scmh1) "ENSG00000010803(SCMH1),ENSG00000102098(SCML2)" " adult stage && oogenesis stage , embryonic stage | >12 hr , embryonic stage--pupal stage " " ovary

, embryonic central nervous system

" "neuroanatomy defective,lethal,recessive,some die during pharate adult stage,heat sensitive,visible,dominant,homeotic,decreased cell number,somatic clone,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,non-suppressor of variegation,non-enhancer of variegation,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,male,female" "dendritic arborizing neuron,axon,sex comb,wing,pigment cell,embryo,egg chamber,interfollicle cell,ectopic,mesothoracic leg,embryonic/first instar larval cuticle,adult abdominal segment 4,adult abdominal segment 5,abdominal tergite 4,male,adult abdominal segment 6,adult abdominal segment 7,abdominal tergite 6,embryonic segment,neuroblast,somatic clone,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval abdominal segment 7,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,larval abdominal segment 8,germline clone,haltere,leg,antenna,female,mesothoracic tergum" DRSC16853 K -0.053243445 -0.288316958 -0.291297165 -0.169238593 1.546783495 0.630053977 FBgn0004110 tin tinman http://flybase.net/reports/FBgn0004110.html "FBgn0002850, FBgn0002944" protein_coding_gene "0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003677=DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0048542=lymph gland development, 0007522=visceral muscle development, 0061320=pericardial nephrocyte differentiation, 0045893=positive regulation of transcription, DNA-templated, 0006355=regulation of transcription, DNA-templated, 0035050=embryonic heart tube development, 0007506=gonadal mesoderm development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007552=metamorphosis, 0071907=determination of digestive tract left/right asymmetry, 0008406=gonad development, 0007507=heart development, 0007280=pole cell migration, 0007435=salivary gland morphogenesis, 0007501=mesodermal cell fate specification, 0061101=neuroendocrine cell differentiation, 0048615=embryonic anterior midgut (ectodermal) morphogenesis, 0035051=cardiocyte differentiation, 0001708=cell fate specification, 0010002=cardioblast differentiation, 0055007=cardiac muscle cell differentiation, 0007510=cardioblast cell fate determination, 0008354=germ cell migration, 0007525=somatic muscle development, 0045892=negative regulation of transcription, DNA-templated, 0007498=mesoderm development" 0005634=nucleus "CG7895, DmNK-4, TIN, NK-4/msh-2, Tin, msh-2, NK4/msh-2, NKX2.5, DROHOXHK4, NK4, Tinman, muscle-specific-homeodomain-2, msh2, HOX, NK-4, DROHOXNK4, tin/NK4" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG7895 16-Dec-15 2015_12 "ENSDARG00000018004(nkx2.5),ENSDARG00000021232(nkx2.7),ENSDARG00000039095(nkx2.3)" " embryonic stage | stage 11 , embryonic stage | stage >11 , embryonic stage | late , embryonic stage , embryonic stage | stage >=11 " " cardiogenic mesoderm

, cardioblast

, embryonic/larval dorsal vessel

, mesoderm | dorsal

, mesoderm

, visceral mesoderm

, visceral mesoderm | restricted

" " embryonic stage | stage 11 , embryonic stage | stage 11-12 , embryonic stage | stage 15-16 , embryonic stage | stage 10 , embryonic stage | stage 8-9 " " cardiogenic mesoderm

, pericardial cell

, mesoderm | dorsal

, trunk mesoderm

, visceral mesoderm

, cardioblast

" "wild-type,neuroanatomy defective,decreased cell death,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,short lived,lethal,flight defective,viable,visible" "midgut muscle,cardioblast,embryonic garland cell,lymph gland primordium,segment border muscle,embryonic/larval dorsal vessel,embryonic/larval visceral muscle,germline cell,gonadal sheath proper primordium,corpus cardiacum primordium,heart primordium,lateral intersegmental nerve root glial cell,bipolar dendrite neuron,dorsal neurohemal organ,transverse nerve & dorsal prothoracic disc,transverse nerve & dorsal mesothoracic disc,transverse nerve & dorsal metathoracic disc,abdominal transverse nerve,embryonic/larval heart & mesoderm,visceral mesoderm,somatic mesoderm,dorsal,embryonic/larval dorsal trunk,midgut constriction 1,midgut constriction 2,midgut constriction 3,embryonic/larval heart,somatic muscle,longitudinal visceral muscle primordium,endoderm,foregut visceral muscle primordium,embryonic brain,embryonic/larval lymph gland,myofibril & larval dorsal vessel, with tinABD,myofibril & larval heart, with tinABD,adult dorsal vessel,myofibril & adult dorsal vessel, with tinABD,adult heart,embryonic/larval aorta,ventral nerve cord,muscle founder cell,embryonic/larval pericardial cell,presumptive embryonic salivary gland,circular visceral muscle primordium,gonad & parasegment 10,gonad & parasegment 11,gonad & parasegment 12,embryonic/larval fat body & parasegment 3,embryonic/larval fat body & parasegment 13,abdominal 2 dorsal transverse muscle 1,abdominal 3 dorsal transverse muscle 1,abdominal 4 dorsal transverse muscle 1,abdominal 5 dorsal transverse muscle 1,abdominal 6 dorsal transverse muscle 1,abdominal 7 dorsal transverse muscle 1,cardiogenic mesoderm,embryonic pericardial cell,anterior embryonic/larval midgut,myofibril & larval dorsal vessel, with tinEC40/tin346,myofibril & larval heart, with tinEC40/tin346,myofibril & adult dorsal vessel, with tinEC40/tin346,pericardial cell,mesothoracic tergum" FBgn0004611 Plc21C Phospholipase C at 21C http://flybase.net/reports/FBgn0004611.html protein_coding_gene "0005509=calcium ion binding, 0004871=signal transducer activity, 0004435=phosphatidylinositol phospholipase C activity" "0006629=lipid metabolic process, 0006661=phosphatidylinositol biosynthetic process, 0035556=intracellular signal transduction, 0007629=flight behavior, 0006651=diacylglycerol biosynthetic process" "Plc21, PLC-21, plc21, Plcbeta21C, PLC-21C, PLC21c, PLC21C, plc21c, PLC[[Beta]], Phospholipase C 21C, phospholipase C, CG4574, plcbeta21c, PLC, plc-21, plc21C" "IPR000008=C2 domain, IPR028407=Phospholipase C, Plc21C, IPR015359=Phosphoinositide-specific phospholipase C, EF-hand-like domain, IPR011992=EF-hand domain pair, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001711=Phospholipase C, phosphatidylinositol-specific, Y domain, IPR016280=Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, IPR000909=Phosphatidylinositol-specific phospholipase C, X domain, IPR001192=Phosphoinositide phospholipase C family, IPR017946=PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG4574 16-Dec-15 2015_12 ENSDARG00000068246(plcb3) "ENSXETG00000007201(PLCB3),ENSXETG00000013371(PLCB2)" "ENSMUSG00000051177(Plcb1),ENSMUSG00000024960(Plcb3),ENSMUSG00000040061(Plcb2)" "ENSG00000182621(PLCB1),ENSG00000149782(PLCB3),ENSG00000137841(PLCB2)" " larval stage , adult stage , embryonic stage -- adult stage , adult stage | female " " larval brain

, head

, oocyte

, thoracico-abdominal ganglion

, adult brain

, optic lobe

" "viable,fertile,neurophysiology defective,dominant,circadian rhythm defective" adult olfactory receptor neuron Or59b FBgn0038923 mRpL35 mitochondrial ribosomal protein L35 http://flybase.net/reports/FBgn0038923.html FBgn0063031 protein_coding_gene 0003735=structural constituent of ribosome "0032543=mitochondrial translation, 0006412=translation, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation" "0005739=mitochondrion, 0005762=mitochondrial large ribosomal subunit" "CG13410, BcDNA:RE35766, MRP-L35" "IPR021137=Ribosomal protein L35, IPR019338=Ribosomal protein L35, mitochondrial" CG13410 16-Dec-15 2015_12 ENSDARG00000070589(mrpl35) WBGene00010812(M01F1.6) ENSXETG00000028100(MRPL35) ENSMUSG00000052962(Mrpl35) ENSG00000132313(MRPL35) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,epithelium,female germline cyst" FBgn0003041 pbl pebble http://flybase.net/reports/FBgn0003041.html "FBgn0010935, FBgn0046405, FBgn0046407" protein_coding_gene "0030676=Rac guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity, 1901981=phosphatidylinositol phosphate binding, 0017048=Rho GTPase binding, 0030215=semaphorin receptor binding, 0005089=Rho guanyl-nucleotide exchange factor activity, 0005096=GTPase activator activity" "0008360=regulation of cell shape, 0043087=regulation of GTPase activity, 0008078=mesodermal cell migration, 0090090=negative regulation of canonical Wnt signaling pathway, 0032507=maintenance of protein location in cell, 1903475=mitotic actomyosin contractile ring assembly, 0007111=meiosis II cytokinesis, 0000281=mitotic cytokinesis, 0007155=cell adhesion, 0050770=regulation of axonogenesis, 0007509=mesoderm migration involved in gastrulation, 0045792=negative regulation of cell size, 0051225=spindle assembly, 0007422=peripheral nervous system development, 0045666=positive regulation of neuron differentiation, 0007110=meiosis I cytokinesis, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development, 0007415=defasciculation of motor neuron axon, 0007399=nervous system development, 0022008=neurogenesis, 0043547=positive regulation of GTPase activity, 0000915=actomyosin contractile ring assembly, 0007443=Malpighian tubule morphogenesis" "0005634=nucleus, 0005654=nucleoplasm, 0005938=cell cortex, 0032154=cleavage furrow" "Pbl, ECT2, Ect-2, PBL, GEF, Pebble, CG8114, PEBBLE, anon-WO0172774.25, 0083/20, pebble, anon-WO0172774.22, l(3)09645, 0542/03, 0293/09" "IPR001357=BRCT domain, IPR026817=Guanine nucleotide exchange factor Ect2, IPR000219=Dbl homology (DH) domain" CG8114 16-Dec-15 2015_12 ENSDARG00000007278(ect2) ENSXETG00000023596(ECT2) ENSG00000114346(ECT2) embryonic stage -- adult stage "lethal - all die during embryonic stage,wild-type,neuroanatomy defective,visible,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,germline clone,cytokinesis defective,mitotic cell cycle defective,cell migration defective,meiotic cell cycle defective,male,male sterile,majority die during embryonic stage,temperature conditional,partially lethal - majority die" "spindle,embryonic/larval cuticle,anterior fascicle & synapse | supernumerary,eye,scutellar bristle,trichogen cell,ectopic,tormogen cell,thecogen cell,temperature conditional,interommatidial bristle,ommatidium,wing vein,presumptive embryonic/larval peripheral nervous system,neuron,intersegmental nerve,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,epithelium,egg chamber,embryonic/larval neuroblast,somatic clone,embryonic/larval brain,embryonic/larval hindgut,mesoderm,Malpighian tubule,embryonic/larval sense organ,precursor,trunk mesoderm,actomyosin contractile ring,centrosome,spermatid & nucleus | supernumerarypbl-NR),Nebenkern,spindle & meiotic cell cycle | malepbl-NR),contractile ring & meiotic cell cycle | malepbl-NR),spermatid & nucleus | supernumerary,spindle & meiotic cell cycle | male,contractile ring & meiotic cell cycle | male,visceral mesoderm,visceral mesoderm derivative,somatic muscle,somatic mesoderm,neuroblast NB6-4 of thorax,neuroblast NB6-4 of abdomen,ventral,abdominal ventral denticle belt,embryo,mitotic telophase,mitotic telophase & spindle,pigment cell,rhabdomereGMR.PF,wing,posterior compartment,wing hair,supernumerary,actomyosin contractile ringprd.RG1,posterior,wing | posterior & wing hairen-e16E,dorsal mesothoracic disc & cell & third instar larvaen-e16E,G2 phase of mitotic cell cycle & dorsal mesothoracic disc & third instar larvaen-e16E,mesoderm | embryonic stage 8,eye | adult stage,S2 cell-line & cell,S2 cell-line & spindle microtubule,ganglion mother cell,mesothoracic tergum" FBgn0002932 neur neuralized http://flybase.net/reports/FBgn0002932.html "FBgn0011395, FBgn0011419, FBgn0011420, FBgn0011422, FBgn0011470, FBgn0046269" protein_coding_gene "0061630=ubiquitin protein ligase activity, 1901981=phosphatidylinositol phosphate binding, 0003677=DNA binding, 0008270=zinc ion binding, 0005515=protein binding" "0007423=sensory organ development, 0042048=olfactory behavior, 0008593=regulation of Notch signaling pathway, 0045314=regulation of compound eye photoreceptor development, 0007616=long-term memory, 0008104=protein localization, 0048749=compound eye development, 0046532=regulation of photoreceptor cell differentiation, 0030707=ovarian follicle cell development, 0048854=brain morphogenesis, 0000209=protein polyubiquitination, 0007422=peripheral nervous system development, 0016360=sensory organ precursor cell fate determination, 0031987=locomotion involved in locomotory behavior, 0001964=startle response, 0045747=positive regulation of Notch signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0007398=ectoderm development, 0051260=protein homooligomerization, 0046331=lateral inhibition, 0002121=inter-male aggressive behavior, 0007498=mesoderm development, 0030718=germ-line stem cell maintenance, 0007399=nervous system development, 0008356=asymmetric cell division" "0005886=plasma membrane, 0048471=perinuclear region of cytoplasm, 0005634=nucleus, 0005737=cytoplasm, 0005768=endosome" "l(3)j6B12, l(3)neo37, l(3)j9B8, BEST:LD21494, neuralized, 1293/09, l(3)j9B9, 1315/05, 0971/15, Neuralised, Neuralized, neu, neuralised, l(3)j9C8, CG11988, Neur, 0328/12" "IPR001841=Zinc finger, RING-type, IPR006573=NEUZ domain, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG11988 16-Dec-15 2015_12 "ENSDARG00000061773(zgc:153175),ENSDARG00000069443,ENSDARG00000069438(si:dkey-82d4.3),ENSDARG00000029452(zgc:110426)" WBGene00017342(F10D7.5) "ENSXETG00000001703(NEURL1B),ENSXETG00000011397(NEURL)" "ENSMUSG00000034413(Neurl1B),ENSMUSG00000006435(Neurl1a)" "ENSG00000214357(NEURL1B),ENSG00000107954(NEURL)" " embryonic stage | early , embryonic stage | 3-9 hr , embryonic stage | stage 5 , wandering third instar larval stage , embryonic stage -- adult stage , larval stage | third instar stage 2 , embryonic stage | stage 9 , embryonic stage , embryonic stage | 0-12 hr , embryonic stage | stage 10 , adult stage | female " " mesectoderm

, neuroblast

, epidermoblast

, mesoderm | presumptive

, mesoderm

, ectoderm

, larval inner optic anlage

, eye-antennal disc | restricted

, larval outer optic anlage

, ventral neurogenic region

, sensory mother cell &&of dorsal mesothoracic disc

, adult neuroblast

" larval stage | third instar eye disc

"viable,smell perception defective,visible,behavior defective,male,neuroanatomy defective,lethal,recessive,neurogenic phenotype,somatic clone,locomotor behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,partially lethal - majority die,memory defective,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective,temperature conditional" "sternopleural bristle,female,male,microchaeta & sternite | male,mushroom body alpha-lobe,ellipsoid body,wing margin,embryonic/larval nervous system,apterous-expressing neuron of the lateral cluster of the thorax,crystal cell,female germline stem cell,germline clone,macrochaeta & mesothoracic tergum | supernumerary | somatic clone,microchaeta,somatic clone,supernumerary,macrochaeta,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,cell autonomous,ectopic,eye,ommatidium,interommatidial bristle,eye photoreceptor cell,wing margin bristle,wing vein,sensory mother cell,rhabdomere,microchaeta & sternite | female,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,wing vein L4,wing vein L5,wing vein L2,wing vein L3,adult thoracic sensillum,neuron & peripheral nervous system,neuroblast,embryonic epidermis,ectoderm,external sensory organ precursor cell,sensory neuron & peripheral nervous system,dorsal mesothoracic disc & sensory mother cell | dorsal/ventral compartment boundary,exit glial cell,peripheral glial cell,embryonic/larval glial cell,embryonic/larval somatic muscle,neuron & eye | supernumerary | somatic clone,germline stem cell,nervous system,presumptive embryonic/larval nervous system,socket,triple row,embryonic myoblast,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,trichogen cell,tormogen cell,eo neuron,thecogen cell,head bristle,thorax & chaeta | somatic clone,external sensory organ precursor cell I,macrochaeta & mesothoracic tergum | somatic clone,pigment cell,cuticle & macrochaeta | somatic clone,embryonic/larval dorsal vessel,precursor,eye photoreceptor cell & ommatidium | ectopic | somatic clone,lens,rhabdomere | cell autonomous | somatic clone,adult midgut,enterocyte,sensillum campaniformium of dorsal radius,distal,sensillum campaniformium,photoreceptor cell,eye disc,wing,dorsocentral bristle,adult epidermis,cone cell,mesothoracic tergum,macrochaeta & head-537.4,chaeta,dorsal cluster neuron,medulla" FBgn0010379 Akt1 Akt1 http://flybase.net/reports/FBgn0010379.html "FBgn0010837, FBgn0013324, FBgn0017365" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0035091=phosphatidylinositol binding, 0005524=ATP binding" "0035556=intracellular signal transduction, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0030307=positive regulation of cell growth, 0008360=regulation of cell shape, 0007424=open tracheal system development, 1901215=negative regulation of neuron death, 0007623=circadian rhythm, 0008361=regulation of cell size, 0046622=positive regulation of organ growth, 0019915=lipid storage, 0043066=negative regulation of apoptotic process, 0007520=myoblast fusion, 0050773=regulation of dendrite development, 0035206=regulation of hemocyte proliferation, 0006979=response to oxidative stress, 0031104=dendrite regeneration, 0048477=oogenesis, 0048680=positive regulation of axon regeneration, 0042306=regulation of protein import into nucleus, 0040014=regulation of multicellular organism growth, 0060292=long term synaptic depression, 0006468=protein phosphorylation, 0045793=positive regulation of cell size, 0040018=positive regulation of multicellular organism growth, 0035264=multicellular organism growth, 0008286=insulin receptor signaling pathway, 0006629=lipid metabolic process, 0008362=chitin-based embryonic cuticle biosynthetic process, 0046620=regulation of organ growth, 0090278=negative regulation of peptide hormone secretion, 0007427=epithelial cell migration, open tracheal system, 0007525=somatic muscle development" "0005737=cytoplasm, 0009986=cell surface, 0005886=plasma membrane, 0043025=neuronal cell body" "Related to PKA to PKC protein kinases, Dakt1, AKT/PKB, akt, CG4006, DAKT1/PKB, related to the A and C kinases, dAkt1, pAkt, Akt1|PKB, PKB/Akt, l(3)04226, dAkt kinase, PKB/dAKT, PKB, Dpkb, RAC, dakt1, DRAC-PK, DAkt1, DAKT1, dAKT, dAkt, dakt, dAKT1, AKT, Akt kinase, Protein kinase B, l(3)89Bq, dAKT/dPKB, DAkt, akt1, DPKB, DRAC-PK66; DRAC-PK85, RacPK, D-Akt, AKT1, Akt, p-Akt, Dakt, dPKB, dAkt/PKB, PKB/AKT, Akt/PKB" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR017892=Protein kinase, C-terminal, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR001849=Pleckstrin homology domain, IPR011009=Protein kinase-like domain" CG4006 16-Dec-15 2015_12 "ENSDARG00000004623,ENSDARG00000063216,ENSDARG00000063400,ENSDARG00000011219(akt2),ENSDARG00000026797(akt2l)" "WBGene00000102(akt-1),WBGene00000103(akt-2)" "ENSXETG00000016986(AKT2),ENSXETG00000008603(AKT1)" "ENSMUSG00000019699(Akt3),ENSMUSG00000001729(Akt1),ENSMUSG00000004056(Akt2)" "ENSG00000117020(AKT3),ENSG00000142208(AKT1),ENSG00000105221(AKT2)" " pupal stage , embryonic stage , adult stage && oogenesis stage , embryonic stage | early , embryonic stage -- adult stage , adult stage | female " "

ubiquitous , nurse cell

" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "chemical resistant,decreased cell death,oxidative stress response defective,circadian rhythm defective,partially lethal - majority die,recessive,small body,decreased cell size,viable,lethal,polyphasic,maternal effect,neurophysiology defective,female sterile,neuroanatomy defective,body size defective,wild-type,visible,somatic clone,lethal - all die before end of embryonic stage,increased cell death,germline clone,cell death defective,cell size defective,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,increased cell size,chemical sensitive,hyperplasia,size defective,planar polarity defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell number,short lived,heat sensitive,long lived,RU486 conditional" "embryonic/larval salivary gland,embryonic/first instar larval cuticle,maternal effect,synapse,embryonic/larval neuromuscular junction,neuromuscular junction | third instar larval stage,neuromuscular junction | third instar larval stage, with Akt11,eye,ommatidium,dendrite | larval stage | somatic clone,rhabdomere,somatic clone,germline clone,head capsule,tracheal branch primordium,embryo,wing hair,wing,wing vein,ectopic,neuromuscular junction | third instar larval stage, with Akt1hs.PS,synapse | supernumeraryD42,dendrite | larval stageppk.PG,wing blade,posterior,wing disc,somatic clone | third instar larval stage,embryonic/larval fat body,fat body,interommatidial bristle,wing margin bristle,1st posterior cell,posterior compartment,adult gut,heat sensitive,RU486 conditional,segment border muscle,embryonic/larval somatic muscle,embryonic myoblast" DRSC14108 IK 1.086317136 2.731984412 0.013081322 -0.071213965 0.141132401 1.622026335 FBgn0020496 CtBP C-terminal Binding Protein http://flybase.net/reports/FBgn0020496.html "FBgn0002353, FBgn0010799, FBgn0024810, FBgn0047318" protein_coding_gene "0008134=transcription factor binding, 0051287=NAD binding, 0070491=repressing transcription factor binding, 0005515=protein binding, 0008022=protein C-terminus binding, 0003714=transcription corepressor activity, 0042803=protein homodimerization activity, 0016616=oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, 0003713=transcription coactivator activity" "0001700=embryonic development via the syncytial blastoderm, 0046427=positive regulation of JAK-STAT cascade, 0016055=Wnt signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0035220=wing disc development, 0006355=regulation of transcription, DNA-templated, 0022416=chaeta development, 0030111=regulation of Wnt signaling pathway, 0016360=sensory organ precursor cell fate determination, 0006357=regulation of transcription from RNA polymerase II promoter, 0055114=oxidation-reduction process, 0043044=ATP-dependent chromatin remodeling" "0031010=ISWI-type complex, 0005634=nucleus, 0005700=polytene chromosome" "CTBP, BcDNA:GH07572, l(3)87De, l(3)03464, EP(3)3528, CG7583, ctbp, 256/16, l(3)03463, l(3)G9, RE61183, G9, 0256/16, Drosophila C-terminal binding protein, C-terminal binding protein, Dm-CtBP, l(3)87DE, lethal(3)87De, C-terminal-Binding-Protein, RE01030, C-terminal-binding protein, dCtBP" "IPR016040=NAD(P)-binding domain, IPR006140=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR006139=D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR029753=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG7583 16-Dec-15 2015_12 "ENSDARG00000019213(zgc:136929),ENSDARG00000057007(ctbp1)" WBGene00006424(ctbp-1) "ENSXETG00000021047(ctbp1),ENSXETG00000006705(TGas101o12.1),ENSXETG00000023631(ctbp2)" "ENSMUSG00000030970(Ctbp2),ENSMUSG00000037373(Ctbp1)" ENSG00000159692(CTBP1) " embryonic stage -- adult stage , embryonic stage , oogenesis stage | stage >S10 , adult stage | female , oogenesis stage " " oocyte

, nurse cell

, germarium

" "visible,dominant,lethal,lethal - all die before end of pupal stage,some die during pupal stage,cell polarity defective,viable,fertile,recessive,polyphasic,maternal effect,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,cell autonomous,somatic clone,female sterile" "adult thoracic sensillum,scutellar bristle,dorsocentral bristle,posterior dorsocentral bristle,anterior dorsocentral bristle,mesothoracic tergum,notal microchaeta,supernumerary,embryonic/first instar larval cuticle,maternal effect,ventral,segment,crystal cell,macrochaeta,ectopic,scutum & macrochaeta | maternal effect,scutellum & macrochaeta | maternal effect,denticle belt,germline clone,posterior scutellar bristle,anterior scutellar bristle,posterior postalar bristle,anterior postalar bristle,posterior supraalar bristle,external sensory organ precursor cell,wing margin,adult thorax,scutellum,wing,interommatidial bristle,wing vein,socket,posterior scutellar bristle | adult stage,anterior scutellar bristle | adult stage,posterior dorsocentral bristle | adult stage,anterior dorsocentral bristle | adult stage,posterior postalar bristle | adult stage,anterior postalar bristle | adult stage,posterior supraalar bristle | adult stage,anterior supraalar bristle | adult stage,presutural bristle | adult stage,posterior notopleural bristle | adult stage,notal microchaeta | adult stage,scutellum | adult stage,mesothoracic tergum | adult stage,cyst progenitor cell,somatic clone,anterior supraalar bristle,posterior notopleural bristle,anterior notopleural bristle,cell autonomous,trichogen cell" DRSC16617 EK 0.766601186 -1.250538266 -0.328054519 -2.087191614 1.576850554 -0.99892624 FBgn0022027 Vps25 Vacuolar protein sorting 25 http://flybase.net/reports/FBgn0022027.html FBgn0033314 protein_coding_gene 0005198=structural molecule activity "0008593=regulation of Notch signaling pathway, 0008283=cell proliferation, 0070086=ubiquitin-dependent endocytosis, 0045199=maintenance of epithelial cell apical/basal polarity, 0000046=autophagic vacuole fusion, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0032509=endosome transport via multivesicular body sorting pathway, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0010669=epithelial structure maintenance, 0016197=endosomal transport, 0030713=ovarian follicle cell stalk formation, 0030154=cell differentiation, 0050680=negative regulation of epithelial cell proliferation, 0042981=regulation of apoptotic process, 0048803=imaginal disc-derived male genitalia morphogenesis, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development" 0000814=ESCRT II complex "l(2)44Db, dVps25, VPS25, ESCRT-II, lethal (2) 44Db, vesicle protein sorting 25, l(2)k08904, CG14750, ESCRT-I, vps25" "IPR008570=ESCRT-II complex, vps25 subunit, IPR014041=ESCRT-II complex, Vps25 subunit, N-terminal winged helix, IPR011991=Winged helix-turn-helix DNA-binding domain" CG14750 16-Dec-15 2015_12 ENSDARG00000059079(zgc:162560) YJR102C(VPS25) WBGene00012193(vps-25) ENSXETG00000024599(VPS25) ENSMUSG00000078656(Vps25) ENSG00000131475(VPS25) "lethal,recessive,female sterile,germline clone,hyperplasia,somatic clone,increased cell death,cell autonomous,lethal - all die before end of larval stage,some die during larval stage,endocytosis defective,large body,developmental rate defective,cell non-autonomous,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell number,cell growth defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg,germline clone,eye,somatic clone,wing,leg,eye disc,wing disc,follicle cell,cell autonomous,cell non-autonomous,ommatidial precursor cluster,endosome & imaginal disc epithelial cell | somatic clone | cell autonomous | third instar larval stage,egg chamber,plasma membrane | somatic clone,epithelium,interfollicle cell,female germline cyst,embryonic/larval digestive system,endosome | somatic clone,eye-antennal disc,adult head,early endosome | somatic clone,embryonic/larval brain,male genitalia" FBgn0063410 l(3)3450-M lethal (3) 3450-M http://flybase.net/reports/FBgn0063410.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024234 gbb glass bottom boat http://flybase.net/reports/FBgn0024234.html FBgn0004788 protein_coding_gene "0005160=transforming growth factor beta receptor binding, 0008083=growth factor activity" "0045887=positive regulation of synaptic growth at neuromuscular junction, 0030509=BMP signaling pathway, 0035222=wing disc pattern formation, 0007391=dorsal closure, 0030707=ovarian follicle cell development, 0007274=neuromuscular synaptic transmission, 0036099=female germ-line stem cell maintenance, 0007474=imaginal disc-derived wing vein specification, 0008586=imaginal disc-derived wing vein morphogenesis, 0046928=regulation of neurotransmitter secretion, 0048636=positive regulation of muscle organ development, 0007179=transforming growth factor beta receptor signaling pathway, 0007528=neuromuscular junction development" "0005576=extracellular region, 0012505=endomembrane system" "BMP, SixtyA, glass-bottomed boat, tgfb-60A, gcn, 60A, glass-bottom boat, Glass Bottom Boat, Gbb-60A, CG5562, GBB, Glass bottom boat, Tgfbeta-60A, gbb-60A, l(2)60A-J, vgr/60A, Tgfb-60, glass bottom boat-60A, TGF-b, Gbb, bone morphogenetic protein, Transforming growth factor beta at 60A, Dm-GBB, bone morphogenic protein, TGFbeta-60A" "IPR029034=Cystine-knot cytokine, IPR001839=Transforming growth factor-beta, C-terminal, IPR001111=Transforming growth factor-beta, N-terminal, IPR017948=Transforming growth factor beta, conserved site, IPR015615=Transforming growth factor-beta-related" CG5562 16-Dec-15 2015_12 "ENSDARG00000015686(bmp6),ENSDARG00000063230(bmp7b),ENSDARG00000018260(bmp7a),ENSDARG00000004965,ENSDARG00000035677(bmp8a)" "ENSXETG00000011272(bmp7),ENSXETG00000007071(BMP5),ENSXETG00000016386(TEgg040b03.1),ENSXETG00000024635(BMP6),ENSXETG00000010940()" "ENSMUSG00000008999(Bmp7),ENSMUSG00000032179(Bmp5),ENSMUSG00000039004(Bmp6),ENSMUSG00000032726(Bmp8a),ENSMUSG00000002384(Bmp8b)" "ENSG00000101144(BMP7),ENSG00000112175(BMP5),ENSG00000153162(BMP6),ENSG00000183682(BMP8A),ENSG00000116985(BMP8B)" " embryonic stage | stage 12-14 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage >14 , embryonic stage | stage >=6 , embryonic stage--pupal stage , adult stage | male " " anterior embryonic/larval midgut

, dorsal mesothoracic disc | restricted

, amnioproctodeal invagination

, embryonic gastric caecum

, ectoderm

, embryonic/larval hindgut

, gastric caecum

, embryonic midgut | restricted

, embryonic central nervous system

, embryonic muscle system

, posterior embryonic/larval midgut

, embryonic/larval foregut

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, visceral mesoderm

, mesoderm

" " embryonic stage | stage 16 , embryonic stage | stage >=15 , larval stage | third instar , embryonic stage | stage 12-16 , embryonic stage | stage >7 " " embryonic/larval hindgut

, embryonic gastric caecum

, dorsal mesothoracic disc | restricted

, posterior embryonic/larval midgut

, motor neuron

, mesoderm

, embryonic central nervous system

, embryonic/larval foregut

, embryonic midgut | restricted

, anterior embryonic/larval midgut

, embryonic neuron

, ventral thoracic disc | restricted

, visceral mesoderm

, eye-antennal disc | restricted

" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,visible,neuroanatomy defective,RU486 conditional,lethal,developmental rate defective,neurophysiology defective,recessive,partially lethal - majority live,wild-type,lethal - all die before end of larval stage,some die during larval stage,somatic clone,female sterile,small body,decreased cell size,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,circadian rhythm defective" "wing vein,ectopic,wing disc,wing,adult brain,RU486 conditional,larva,fat body,type I bouton | third instar larval stage,female germline stem cell,heat sensitive,male germline stem cell,posterior crossvein,wing vein L5,wing vein L4,distal,testis,spermatocyte,bouton,synaptic vesicle,postsynaptic membrane,crossvein,scutellar bristle,macrochaeta,wing vein L2,eye,ommatidium,dorsocentral bristle,wing margin bristle,anterior crossvein,wing cell,submarginal cell,2nd posterior cell,dil cell,wing basal cell 2,3rd posterior cell,wing sensillum,vibrissae,mesothoracic bristle,metathoracic bristle,leg,hemocyte,imaginal disc,embryonic/larval cuticle,telson,embryonic/larval posterior spiracle,stigmatophore,midgut constriction 1,anterior embryonic/larval midgut,synapse & neuromuscular junction, with gbbUAS.cKa,synapse, with gbbUAS.cKa,embryonic/larval fat body,gastric caecum,wing blade,anterior compartment,somatic clone,wing vein L3,cell non-autonomous,embryonic/larval digestive system,embryonic/larval brain,wing basal cell 1,1st posterior cell,posterior compartment,synapse & neuromuscular junction, with gbb2/gbb1,synapse, with gbb2/gbb1,triple row,type I bouton,supernumerary | third instar larval stage,NMJ bouton,NMJ bouton | third instar larval stage" FBgn0267978 ap apterous http://flybase.net/reports/FBgn0267978.html "FBgn0000099, FBgn0005618" protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" "0007526=larval somatic muscle development, 0048735=haltere morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0007479=leg disc proximal/distal pattern formation, 0035218=leg disc development, 0007517=muscle organ development, 0007472=wing disc morphogenesis, 0045165=cell fate commitment, 0007559=histolysis, 0007399=nervous system development, 0006351=transcription, DNA-templated, 0007476=imaginal disc-derived wing morphogenesis, 0007450=dorsal/ventral pattern formation, imaginal disc, 0007411=axon guidance, 0007481=haltere disc morphogenesis, 0048190=wing disc dorsal/ventral pattern formation, 0036011=imaginal disc-derived leg segmentation" 0005634=nucleus "Ap, LIM, CG8376, trw, APTEROUS, neuro, tornwing, neuromuscular, Apt, apteroys, Xasta, no-wings, apterous, Apterous, Xa, blt, AP, S-2a" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001781=Zinc finger, LIM-type, IPR001356=Homeobox domain" CG8376 16-Dec-15 2015_12 "ENSDARG00000031222(lhx2b),ENSDARG00000056979(lhx9),ENSDARG00000037964" WBGene00006654(ttx-3) "ENSXETG00000020776(),ENSXETG00000009957(LHX9)" "ENSMUSG00000000247(Lhx2),ENSMUSG00000019230(Lhx9)" "ENSG00000106689(LHX2),ENSG00000143355(LHX9)" "visible,recessive,female sterile,male sterile,viable,flightless,short lived,lethal,neuroanatomy defective,sterile,uncoordinated,increased cell death,dominant,reduced,mating defective,female,courtship behavior defective,male,some die during immature adult stage,heat sensitive,fertile,male fertile,female fertile,stress response defective,heat stress response defective,semi-fertile,partially,good,wild-type,partially lethal - majority live,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "nurse cell,adult corpus allatum,embryonic/larval fat body,ovary,wing,haltere,wing disc,dorsal/ventral compartment boundary,wing margin,direct flight muscle,basalar muscle 51,basalar muscle 52,muscle of first axillary 53,muscle of third axillary 54,indirect flight muscle,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,longitudinal connective,presumptive embryonic/larval central nervous system,axon,interneuron,embryonic protocerebrum,embryonic deuterocerebrum,embryonic/larval neuron,heat sensitive,wing margin bristle,tarsal segment 4,scutellum,pretarsus,egg chamber,hemolymph,corpus allatum,scutellar bristle,dorsocentral bristle,peritrophic membrane,abdominal 2 lateral transverse muscle 1,abdominal 3 lateral transverse muscle 1,abdominal 4 lateral transverse muscle 1,abdominal 5 lateral transverse muscle 1,abdominal 6 lateral transverse muscle 1,abdominal 7 lateral transverse muscle 1,abdominal 2 lateral transverse muscle 2,abdominal 3 lateral transverse muscle 2,abdominal 4 lateral transverse muscle 2,abdominal 5 lateral transverse muscle 2,abdominal 6 lateral transverse muscle 2,abdominal 7 lateral transverse muscle 2,abdominal 2 lateral transverse muscle 3,abdominal 3 lateral transverse muscle 3,abdominal 4 lateral transverse muscle 3,abdominal 5 lateral transverse muscle 3,abdominal 6 lateral transverse muscle 3,abdominal 7 lateral transverse muscle 3,scutum,mesothoracic tergum,dorsal triple row,medial triple row,ventral triple row,anterior supraalar bristle,posterior supraalar bristle,anterior postalar bristle,adult fat body,mesothoracic leg,metathoracic leg,wing pouch,male accessory gland,postalar bristle,posterior compartment,wing vein,embryonic/larval somatic muscle,abdominal 2 ventral acute muscle 3,abdominal 3 ventral acute muscle 3,abdominal 4 ventral acute muscle 3,abdominal 5 ventral acute muscle 3,abdominal 6 ventral acute muscle 3,abdominal 7 ventral acute muscle 3,costal cell,posterior notopleural bristle,posterior postalar bristle,posterior scutellar bristle,microchaeta & thorax,thorax,mesothoracic suture,macrochaeta & thorax | dorsal,dorsal compartment,A1-7 lateral transverse muscle,ectopic,ventral compartment,distal,somatic clone,A1-7 segment border muscle" FBgn0004666 sim single-minded http://flybase.net/reports/FBgn0004666.html "FBgn0003333, FBgn0003409" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0046982=protein heterodimerization activity, 0000982=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0035225=determination of genital disc primordium, 0007398=ectoderm development, 0007411=axon guidance, 0007420=brain development, 0007628=adult walking behavior, 0007409=axonogenesis, 0040011=locomotion, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007417=central nervous system development, 0007418=ventral midline development, 0007419=ventral cord development" "0005667=transcription factor complex, 0005634=nucleus, 0005737=cytoplasm" "1110/04, 1002/10, single minded, 1330/08, 0716/08, l(3)E320, 1479/04, 1111/10, Sim, 0483/09, 0953/08, SIM, schm, 0899/14, l(3)87Ea, singleminded, Single minded, CG7771, l(3)s8, 1034/02, bHLHe16, Singled-minded, l(3)S8, Single-minded, schmal, shm, l(3)RD, 1050/13, S8" "IPR013655=PAS fold-3, IPR001067=Nuclear translocator, IPR001610=PAC motif, IPR013767=PAS fold, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR000014=PAS domain" CG7771 16-Dec-15 2015_12 "ENSDARG00000013789(sim1b),ENSDARG00000039935(sim2),ENSDARG00000023316(sim1a)" WBGene00001851(hif-1) "ENSMUSG00000062713(Sim2),ENSMUSG00000019913(Sim1)" "ENSG00000159263(SIM2),ENSG00000112246(SIM1)" " embryonic stage , embryonic stage | stage 10-12 " " ventral midline

, mesectoderm

, somatic mesoderm

, myoblast &&of larval muscle system

" " embryonic stage , embryonic stage | stage 10-15 " " ventral oblique muscle

, VUM neuron

, myoblast &&of larval muscle system

, somatic mesoderm

, neuroblast MNB

, midline glial cell

, embryonic foregut

ventral & anterior , mesectoderm

" "viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,lethal,heat sensitive,sterile,visible,courtship behavior defective,optomotor response defective,locomotor behavior defective,female sterile,male sterile,increased cell death,partially,decreased cell number,somatic clone,pair rule phenotype" "ventral arm of pharyngeal sclerite,embryonic head,embryonic epidermis,ventral nerve cord commissure,presumptive embryonic/larval central nervous system,anal slit,heat sensitive,genitalia,analia,optic chiasma,lobula,adult central complex,fan-shaped body,protocerebral bridge,longitudinal connective,female analia,adult hindgut,gonopod thorn bristle,vulva,ovary,anal plate,clasper,penis,testis,lamina forming neuroblast,embryonic/larval brain,eye photoreceptor cell & axon,ventral nerve cord,embryonic somatic muscle,ventral,embryonic central brain,ganglion mother cell GMC1-1a,RP2 motor neuron,ectopic,RP2sib neuron,embryonic ventral epidermis,ventral midline,commissure,neuromere,midline glial cell,MP1 neuron,abdominal 1 dorsal VUM motor neuron,abdominal 2 dorsal VUM motor neuron,abdominal 3 dorsal VUM motor neuron,abdominal 4 dorsal VUM motor neuron,abdominal 5 dorsal VUM motor neuron,abdominal 6 dorsal VUM motor neuron,abdominal 7 dorsal VUM motor neuron,abdominal 1 ventral VUM motor neuron,abdominal 2 ventral VUM motor neuron,abdominal 3 ventral VUM motor neuron,abdominal 4 ventral VUM motor neuron,abdominal 5 ventral VUM motor neuron,abdominal 6 ventral VUM motor neuron,abdominal 7 ventral VUM motor neuron,abdominal 1 lateral VUM motor neuron,abdominal 2 lateral VUM motor neuron,abdominal 3 lateral VUM motor neuron,abdominal 4 lateral VUM motor neuron,abdominal 5 lateral VUM motor neuron,abdominal 6 lateral VUM motor neuron,abdominal 7 lateral VUM motor neuron,neuroblast MNB,dorsal neurohemal organ,central nervous system,VUM precursor,MP1 precursor,embryonic/larval anal pad,genital disc primordium,muscle founder cell,adult salivary gland primordium,embryonic neuroblast,cell cycle,ventral nerve cord primordium & mitotic cell cycle,peripheral glial cell,neuroglioblast,medial-most cell body glial cell,medial cell body glial cell,exit glial cell,axon | somatic clone | third instar larval stage,denticle belt,ventral nervous system,ventral midline neuron,mesectoderm,cephalopharyngeal skeleton,dendritic arborizing neuron,axon,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,VUM neuron,macrophage,neuron,embryonic/larval cuticle,embryonic segment,embryonic brain,eye,adult head,antenna,trichogen cell" FBgn0011692 pav pavarotti http://flybase.net/reports/FBgn0011692.html FBgn0022345 protein_coding_gene "0005524=ATP binding, 0008017=microtubule binding, 0003777=microtubule motor activity" "0016321=female meiosis chromosome segregation, 0030111=regulation of Wnt signaling pathway, 0051533=positive regulation of NFAT protein import into nucleus, 0007525=somatic muscle development, 0000915=actomyosin contractile ring assembly, 0000910=cytokinesis, 0022008=neurogenesis, 0007018=microtubule-based movement, 0090307=mitotic spindle assembly, 1903562=microtubule bundle formation involved in mitotic spindle midzone assembly, 0051298=centrosome duplication, 0001709=cell fate determination, 0007422=peripheral nervous system development, 0007052=mitotic spindle organization, 0007224=smoothened signaling pathway, 0070507=regulation of microtubule cytoskeleton organization, 0000281=mitotic cytokinesis, 0000916=actomyosin contractile ring contraction, 0032507=maintenance of protein location in cell" "0005871=kinesin complex, 0030496=midbody, 0032154=cleavage furrow, 0005930=axoneme, 0035323=male germline ring canal, 1990023=mitotic spindle midzone, 0098549=somatic ring canal, 0005828=kinetochore microtubule, 0005634=nucleus, 0005819=spindle, 0035324=female germline ring canal, 0070938=contractile ring, 0005813=centrosome" "Pavarroti, PAV, 2A12MEL, Pav, KIF 23, KIF23, DmPAV, pav-KLP, kinesin-6, Pav-KLP, group D, PAV/KLP, PAV-KLP, DmKLP1/pav, Kinesin-6, Pav-klp, 0973/08, CG1258, PAV-MKLP, anon-EST:fe2A12, Pavarotti-KLP, Mklp1, anon2A12, Pavarotti, pav-Klp, anon-fast-evolving-2A12, Pav KLP, Mitotic kinesin-like protein 1, Pavarotti kinesin-like protein, DmPav, DmMKLP1, Pav-Klp, PavKLP, 0934/13, 2A12, Pavarotti KLP" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain, IPR027640=Kinesin-like protein" CG1258 16-Dec-15 2015_12 ENSDARG00000014943(kif23) WBGene00006974(zen-4) ENSXETG00000007829(Q5XGE1_XENTR) ENSMUSG00000032254(Kif23) ENSG00000137807(KIF23) " , embryonic stage | embryonic cycle 16 , adult stage " " cell

, organism

, stage S7 oocyte

, egg chamber && ring canal

, nurse cell

" "cytokinesis defective,neuroanatomy defective,recessive,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,dominant,wild-type,somatic clone,mitotic cell cycle defective,female sterile,viable,fertile,female fertile,visible" "nucleus,ventral nerve cord,embryonic epidermis,nucleusGN50),S2 cell-line,perinuclear region of cytoplasm,neuron,presumptive embryonic/larval peripheral nervous system,cycle 16 embryo,spindle,mitosis & nuclear chromosome,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,neuron & peripheral nervous system,mitotic telophase,mitotic telophase & spindle,actomyosin contractile ring,mushroom body & axon | somatic clone,microtubule,spindle | embryonic cycle 16,centrosome | embryonic cycle 16,abdominal ventral denticle belt,embryonic/larval somatic muscle,egg chamber,oocyte,nurse cell & microtubulemat.ë±Tub67C.THsimVP16,ring canal,actin filament & nurse cellmat.ë±Tub67C.THsimVP16,nurse cell,egg,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08730 I 2.426854294 -0.330624867 0.773645307 -0.745803994 -0.35855974 0.988264344 FBgn0015790 Rab11 Rab11 http://flybase.net/reports/FBgn0015790.html "FBgn0004235, FBgn0011334" protein_coding_gene "0032403=protein complex binding, 0005525=GTP binding, 0005515=protein binding, 0032794=GTPase activating protein binding, 0003924=GTPase activity" "0048749=compound eye development, 0001745=compound eye morphogenesis, 0048599=oocyte development, 0030866=cortical actin cytoskeleton organization, 0007112=male meiosis cytokinesis, 0034334=adherens junction maintenance, 0016360=sensory organ precursor cell fate determination, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0048210=Golgi vesicle fusion to target membrane, 0048477=oogenesis, 0022416=chaeta development, 0045478=fusome organization, 0008103=oocyte microtubule cytoskeleton polarization, 0007349=cellularization, 0007298=border follicle cell migration, 0046664=dorsal closure, amnioserosa morphology change, 0000916=actomyosin contractile ring contraction, 0042998=positive regulation of Golgi to plasma membrane protein transport, 0042052=rhabdomere development, 0019730=antimicrobial humoral response, 0050807=regulation of synapse organization, 0007317=regulation of pole plasm oskar mRNA localization, 2000039=regulation of trichome morphogenesis, 0007391=dorsal closure, 0030718=germ-line stem cell maintenance, 0051642=centrosome localization, 0032482=Rab protein signal transduction, 0030723=ovarian fusome organization, 0042078=germ-line stem cell division, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0006897=endocytosis, 1990182=exosomal secretion, 0048137=spermatocyte division, 0016192=vesicle-mediated transport, 0031532=actin cytoskeleton reorganization, 0007394=dorsal closure, elongation of leading edge cells" "0060187=cell pole, 0031982=vesicle, 0048471=perinuclear region of cytoplasm, 0005813=centrosome, 0005811=lipid particle, 0043195=terminal bouton, 0031410=cytoplasmic vesicle, 0005815=microtubule organizing center, 0005768=endosome, 0055037=recycling endosome, 0005635=nuclear envelope, 0005776=autophagic vacuole, 0005737=cytoplasm, 0070732=spindle envelope, 0045202=synapse, 0043025=neuronal cell body, 0045169=fusome, 0030140=trans-Golgi network transport vesicle, 0005794=Golgi apparatus, 0005886=plasma membrane, 0032154=cleavage furrow" "O18335, l(3)93Bi, CG5771, rlr7, DRab11, Drab11, Rab 11, rab-11, AAF55850, Rab-protein 11, Dm Rab11, DmRab11, RAB11, lethal(3)93Bi, Rab-r11, Rab-11, DRAB11, rab11, l(3)j2D1" "IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003579=Small GTPase superfamily, Rab type" CG5771 16-Dec-15 2015_12 "ENSDARG00000041450(rab11a),ENSDARG00000041878(rab11b),ENSDARG00000023324(zgc:92772)" "YGL210W(YPT32),YER031C(YPT31)" WBGene00004274(rab-11.1) "ENSXETG00000006639(rab11a),ENSXETG00000025484(rab11b),ENSXETG00000021890(BC075268.1)" "ENSMUSG00000004771(Rab11a),ENSMUSG00000077450(Rab11b)" "ENSG00000103769(RAB11A),ENSG00000185236(RAB11B)" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "female semi-sterile,female sterile,partially lethal - majority die,meiotic cell cycle defective,male,cytokinesis defective,recessive,visible,fertile,lethal,neuroanatomy defective,viable,size defective,cell migration defective,cell lethalcell lethal,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,increased cell death,neurophysiology defective,conditional,sterile" "macrochaeta,actin cytoskeleton | embryonic stage,spermatid,Nebenkern,nucleus | embryonic stage,germline cell,acroblast,spindle,contractile ring,cleavage furrow,Golgi-associated vesicle,neuromuscular junction,NMJ bouton,supernumerary,microchaeta,posterior scutellar bristle,bouton,border follicle cell,embryonic/first instar larval cuticle,embryonic leading edge cell,optic cartridge | third instar larval stage,eye,photoreceptor | third instar larval stage,ommatidium | third instar larval stage,egg chamber,germline clone,rhabdomere,somatic clone,multivesicular body & eye photoreceptor cell | somatic clone[-],dorsocentral bristle,scutellar bristle,tormogen cell,embryonic dorsal epidermis,amnioserosa,interommatidial bristle,eye photoreceptor cell,ommatidium,fusome | germline clone,germline stem cell,egg,female germline stem cell,cell-cell adherens junction | somatic clone,stem cell fusome,nurse cell ring canal,female germline cyst,oocyte,rhabdomerehs.PB,wing hair | pupal stage,multivesicular bodyhs.PB,photoreceptor cell,garland cell,embryonic/larval dorsal trunk,syncytial blastoderm embryo,adult midgut epithelium,chaeta & antenna,eye disc,cone cell,primary pigment cell,trichogen cell,socket,rhabdomere | conditionalninaE.PT,chaeta,mesothoracic tergum,wing,wing vein,wing hair,macrophage,centrosomeneur-P72,external sensory organ precursor cell I,epithelium" DRSC16809 I 0.89443948 -1.50747614 -0.569862749 -0.333742244 0.205974943 0.826598135 FBgn0015371 chn charlatan http://flybase.net/reports/FBgn0015371.html "FBgn0010506, FBgn0026007, FBgn0033992, FBgn0046116" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding, 0005515=protein binding" "0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0009612=response to mechanical stimulus, 0007423=sensory organ development, 0007526=larval somatic muscle development, 0007399=nervous system development, 0042683=negative regulation of compound eye cone cell fate specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007422=peripheral nervous system development, 0001700=embryonic development via the syncytial blastoderm, 0048813=dendrite morphogenesis, 0001654=eye development" 0005634=nucleus "Chn, taco, EPIL6, EPIL#6, l(2)02064, CG11798, l(2)k04218, Charlatan, anon-EST:Liang-1.13, clone 1.13" "IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like" CG11798 16-Dec-15 2015_12 "neuroanatomy defective,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,heat sensitive,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,macrochaeta,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,cone cell,eye,chaeta,supernumerary,mesothoracic tergum,eye photoreceptor cell,somatic clone,wing disc,morphogenetic furrow,external sensory organ,ectopic,mesothoracic bristle,ventral abdominal cluster,dorsal abdominal cluster,chordotonal organ & neuron,mesothoracic tergum & macrochaeta | somatic clone,scutellar bristle,trichogen cell,dorsal mesothoracic disc & sensory mother cell | somatic clone,heart primordium,mesothoracic tergum & macrochaeta-537.4,anterior notopleural bristle,posterior notopleural bristle,posterior supraalar bristle,anterior postalar bristle,posterior postalar bristle,dorsocentral bristle,mesothoracic tergum & macrochaetaap-md544,anterior supraalar bristle,microchaeta,wing & chaeta | ectopicC-765,mesothoracic tergum & macrochaeta | ectopicMS248,head bristle,dorsal mesothoracic disc & sensory mother cell | ectopicMS248,metathoracic bristle,wing & chaeta | ectopicBx-MS1096,dorsal mesothoracic disc & sensory mother cell | ectopicBx-MS1096,sensory neuron,embryonic/larval hemocyte | third instar larval stage" DRSC06086 E 1.004031126 -0.66729064 1.900963321 1.596566217 -0.290107229 -0.428332752 FBgn0003525 stg string http://flybase.net/reports/FBgn0003525.html "FBgn0011019, FBgn0011315, FBgn0011317, FBgn0011354, FBgn0011428, FBgn0043376" protein_coding_gene "0004726=non-membrane spanning protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity" "0000087=mitotic M phase, 0007424=open tracheal system development, 0007346=regulation of mitotic cell cycle, 0006470=protein dephosphorylation, 0008283=cell proliferation, 0008284=positive regulation of cell proliferation, 0007088=regulation of mitotic nuclear division, 0007099=centriole replication, 0007498=mesoderm development, 0007369=gastrulation, 0007030=Golgi organization, 0007422=peripheral nervous system development, 0045930=negative regulation of mitotic cell cycle, 0045792=negative regulation of cell size, 0000086=G2/M transition of mitotic cell cycle, 0046331=lateral inhibition, 0045977=positive regulation of mitotic cell cycle, embryonic, 0060305=regulation of cell diameter, 0000278=mitotic cell cycle, 0045931=positive regulation of mitotic cell cycle" "0005694=chromosome, 0005634=nucleus" "EP1213, 0967/05, STG, String/Cdc25 phosphatase, Cdc25[string], Cdc25[Stg], cdc25, SY3-4, Stg, l(3)01235, String/Cdc25, 0730/13, 0245/03, 1083/13, Cdc25[stg], 5473, clone 2.21, string, 0980/06, CDC25[string], string/cdc25, Cdc25c, Cdc25, 0896/05, l(3)j1E3, l(3)s2213, CDC25, Suppressor of rux 3A, 0439/22, 0224/06, str/cdc25, String, S(rux)3A, st, l(3)j1D3, CG1395, stg[cdc25], 1143/02, 1089/08, l(3)j3D1, anon-EST:Liang-2.21, l(3)j10B9, Cdc25[String], cdc25[string], cdc25/string" "IPR001763=Rhodanese-like domain, IPR000751=M-phase inducer phosphatase" CG1395 16-Dec-15 2015_12 ENSDARG00000010792(cdc25) WBGene00000386(cdc-25.1) "ENSXETG00000006710(CDC25C),ENSXETG00000012740(CDC25B),ENSXETG00000021310(cdc25a)" "ENSMUSG00000027330(Cdc25b),ENSMUSG00000044201(Cdc25c),ENSMUSG00000032477(Cdc25a)" "ENSG00000101224(CDC25B),ENSG00000158402(CDC25C),ENSG00000164045(CDC25A)" " spermatogenesis && adult stage , embryonic stage | stage >=10 , larval stage , adult stage && oogenesis stage , embryonic stage | early , adult stage | female " " testis

, Malpighian tubule | restricted

, eye-antennal disc

, oocyte

, nurse cell

, optic lobe

" "female sterile,lethal,recessive,viable,female fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile,size defective,dominant,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,visible,wild-type,mitotic cell cycle defective,increased cell size,male sterile,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die during pupal stage,decreased cell size,cell shape defective,increased cell number" "wing blade,macrochaeta,ventral nerve cord commissure,longitudinal connective,scutellar bristle,eye,haltere,wing,embryonic/first instar larval cuticle,denticle belt,crystal cell,mitotic cell cycle,plasmatocyte,trichogen cell,ectopic,tormogen cell,thecogen cell,ommatidium,eye photoreceptor cell,eye disc,photoreceptor cell,photoreceptor cell R2,photoreceptor cell R5,germline cyst,cystocyte,ventral furrow,ganglion mother cell,mitotic cell cycle | ectopic,wing disc,eye-antennal disc,scutum & macrochaeta,ganglion mother cell GMC4-2a,RP2sib neuron,aCC neuron,precursor,pCC neuron,macrochaeta & adult head,macrochaeta & adult thorax,macrochaeta & scutellum,macrochaeta & wing,nuclear chromosome,nuclear membrane,spindle,larval hindgut & ectoderm,neuron,presumptive embryonic/larval peripheral nervous system,embryonic/larval brain,socket,mitotic cell cycle | embryonic stage,neuropil,embryonic/larval hindgut,microchaeta,sensory mother cell,somatic clone,cell cycle,mitotic cell cycle | somatic clone,glial cell & eye disc | ectopicbi-omb-Gal4,spermatogonial cyst,oocyte,chaeta,wing cell,mitotic cell cycle & eye disc,imaginal disc,multidendritic neuron,external sensory organ,chordotonal organ,follicle cell,embryonic neuroblast,cycle 14 embryo,centriole,neuroblast NB6-4 of thorax,neuroblast NB6-4 of abdomen,cardioblast,pericardial cell,embryo" DRSC17071 EK -1.183141306 -1.478998275 -0.842647849 -3.720270765 8.759802607 12.04724024 FBgn0000097 aop anterior open http://flybase.net/reports/FBgn0000097.html "FBgn0003123, FBgn0005623, FBgn0026827" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0019904=protein domain specific binding, 0043565=sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0005515=protein binding" "0000165=MAPK cascade, 0001709=cell fate determination, 0008406=gonad development, 0048749=compound eye development, 0007517=muscle organ development, 0007254=JNK cascade, 0035155=negative regulation of terminal cell fate specification, open tracheal system, 0060233=oenocyte delamination, 0030178=negative regulation of Wnt signaling pathway, 0008340=determination of adult lifespan, 0035157=negative regulation of fusion cell fate specification, 0046580=negative regulation of Ras protein signal transduction, 0045467=R7 cell development, 0045316=negative regulation of compound eye photoreceptor development, 0045596=negative regulation of cell differentiation, 0048747=muscle fiber development, 0048813=dendrite morphogenesis, 0045678=positive regulation of R7 cell differentiation, 0006897=endocytosis, 0001751=compound eye photoreceptor cell differentiation, 0048666=neuron development, 0050767=regulation of neurogenesis, 0090175=regulation of establishment of planar polarity, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045610=regulation of hemocyte differentiation, 0007391=dorsal closure, 0046533=negative regulation of photoreceptor cell differentiation, 0045892=negative regulation of transcription, DNA-templated, 0007464=R3/R4 cell fate commitment, 0007298=border follicle cell migration" "0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus, 0005654=nucleoplasm" "Aop/Yan, pokkuri, Anterior open, DROYANET, pok, unnamed, aop/yan, yan/pok, Aop, DROYANETSB, YAN, fus6, AOP, anterior-open, Yan, SGP cluster fusion defects 6, SK2-1, Anterior Open, yan, CG3166" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain, IPR013761=Sterile alpha motif/pointed domain, IPR003118=Pointed domain" CG3166 16-Dec-15 2015_12 ENSDARG00000069193(etv7) ENSXETG00000008919(etv6) ENSMUSG00000030199(Etv6) "ENSG00000139083(ETV6),ENSG00000010030(ETV7)" " larval stage | third instar , embryonic stage " imaginal disc

" pupal stage , embryonic stage | stage 10 , larval stage , embryonic stage | stage 13 " " pigment cell

, epidermis

, eye-antennal disc

, embryonic/larval tracheal system

, cone cell

" "lethal,viable,visible,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,poor,sterile,partially,planar polarity defective,polyphasic,partially lethal - majority die,female sterile,male sterile,reduced,somatic clone,heat sensitive,increased cell death,neuroanatomy defective,size defective" "scutellar bristle,ectopic,tormogen cell,trichogen cell,adult abdomen & trichogen cell-537.4,wing,wing vein,border follicle cell,somatic clone,presumptive embryonic/larval muscle system,photoreceptor cell R7,eye,ommatidium,eye photoreceptor cell,supernumerary,posterior compartment,midline glial cell,cone cell,precursor,cell autonomous,embryonic/larval tracheal system,embryonic somatic muscle,segment border muscle,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,embryonic/larval oenocyte,gonad,gonadal sheath proper primordium,tarsal segment,denticle,embryonic/first instar larval cuticle,embryonic epidermis,anterior,dorsal,lch5 neuron,eye disc,photoreceptor cell R8,heat sensitive,photoreceptor cell,macrochaeta & eye,pigment cell,mesoderm,embryonic/larval pericardial cell,A1-7 dorsal acute muscle 1,abdominal lateral pentascolopidial chordotonal organ lch5,chordotonal organ,follicle cell,tracheal lumen,embryonic/larval dorsal trunk,tracheal fusion cell,terminal tracheal cell,cephalopharyngeal skeleton,dorsal pouch,eye-antennal disc,visual primordium,stomatogastric nervous system,Bolwig organ,rhabdomere,endocytic vesicle,embryonic/larval ganglionic branch,presumptive embryonic/larval central nervous system,wing disc,macrochaeta,morphogenetic furrow,embryonic dorsal epidermis,sensory neuron & axon & embryorepo,motor neuron | embryonic stage,presumptive embryonic/larval peripheral nervous system,fascicle | embryonic stage,embryo,embryonic/larval dorsal vessel | embryonic stage,embryonic/larval somatic muscle,commissure,longitudinal connective,denticle row 1,cardiogenic mesoderm,melanotic mass,hemocyte,lamellocyte,crystal cell,muscle fiber,muscle founder cell,interommatidial bristle,secondary neuroblast,ectopic | larval stage" FBgn0002521 pho pleiohomeotic http://flybase.net/reports/FBgn0002521.html "FBgn0005575, FBgn0024914" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding, 0003682=chromatin binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0031490=chromatin DNA binding, 0046872=metal ion binding" "0006338=chromatin remodeling, 0016458=gene silencing, 0006342=chromatin silencing, 0006355=regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated, 0006265=DNA topological change, 0048813=dendrite morphogenesis, 0010629=negative regulation of gene expression" "0005634=nucleus, 0000790=nuclear chromatin, 0005704=polytene chromosome band, 0031011=Ino80 complex, 0005703=polytene chromosome puff, 0031519=PcG protein complex, 0005700=polytene chromosome" "l(4)pho, l(4)OC-1, l(4)102EFc, l(4)29, l(4)BU-2, PHO/YY1, YY1, dYY1, CG17743, Pho, Peiohomeotic, pleihomeotic, PHO, Pleiohomeotic, polyhomeotic" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG17743 16-Dec-15 2015_12 "ENSG00000198767,ENSG00000100811(YY1)" "neuroanatomy defective,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,antenna,sex comb,unguis,mesothoracic leg,metathoracic leg,tarsal segment,pupal abdomen,female accessory gland,embryonic head,maternal effect,embryonic thorax,embryonic abdominal segment 6,embryonic abdominal segment 7,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,adult abdominal segment 4,embryonic abdominal segment,embryonic abdominal segment 8,ectopic,embryonic thoracic segment" FBgn0000635 Fas2 Fasciclin 2 http://flybase.net/reports/FBgn0000635.html "FBgn0026682, FBgn0027230, FBgn0028323, FBgn0040201, FBgn0040202" protein_coding_gene 0005515=protein binding "0072499=photoreceptor cell axon guidance, 0035159=regulation of tube length, open tracheal system, 0007528=neuromuscular junction development, 0008038=neuron recognition, 0048803=imaginal disc-derived male genitalia morphogenesis, 0035158=regulation of tube diameter, open tracheal system, 0007413=axonal fasciculation, 0008355=olfactory learning, 0001746=Bolwig's organ morphogenesis, 0007614=short-term memory, 0008045=motor neuron axon guidance, 0008582=regulation of synaptic growth at neuromuscular junction, 0016319=mushroom body development, 0050808=synapse organization, 0007611=learning or memory, 0072553=terminal button organization, 0035152=regulation of tube architecture, open tracheal system, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0008360=regulation of cell shape, 0048149=behavioral response to ethanol, 0050803=regulation of synapse structure or activity, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0048667=cell morphogenesis involved in neuron differentiation, 0007612=learning" "0005737=cytoplasm, 0005829=cytosol, 0043005=neuron projection, 0097482=muscle cell postsynaptic density, 0042995=cell projection, 0045211=postsynaptic membrane, 0042734=presynaptic membrane, 0048786=presynaptic active zone, 0031594=neuromuscular junction, 0030424=axon, 0036062=presynaptic periactive zone, 0005886=plasma membrane, 0016021=integral component of membrane" "fasciclin-II, fas-II, Fasciclin II, Fasii, fas2, FascII, Ab 1D4, Fas II, FAS II, fasciclin2, mAB1D4, mAb1D4, Fasciclin, EG:EG0007.3, fasciclin 2, fas II, FASCICLIN, l(1)G0336, 1D4, Fasiclin II, Fasciclin-2, FAS2, mAb 1D4, FASCICLIN II, Fasciculin II, l(1)G0293, FAS 11, l(1)G0032, Fas-II, Fascilin II, Fascicilin II, FasII, Fasciclin2, Fas, clone 1.60, l(1)G0081, CT12301, FASII, Fas 2, fasciclin II, FasciclinII, l(1)G0048, fasII, CG3665, fasciclinII, fasciclin-2, anon-EST:Liang-1.60, MAB1D4" "IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR009138=Neural cell adhesion, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG3665 16-Dec-15 2015_12 "ENSDARG00000017466(ncam2),ENSDARG00000055669,ENSDARG00000056181(ncam1),ENSDARG00000007220(ncam3)" "ENSXETG00000011665(NCAM1),ENSXETG00000007054(NCAM2)" "ENSMUSG00000022762(Ncam2),ENSMUSG00000039542(Ncam1)" "ENSG00000154654(NCAM2),ENSG00000149294(NCAM1)" " embryonic stage | stage 9-11 , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 14-16 , embryonic stage | stage 16 , embryonic stage | stage 13-16 , embryonic stage | stage 13 " " tritocerebral neuroblast | subset

, ectoderm | restricted

, procephalic neurogenic region | restricted

, aCC neuron

, pCC neuron

, intersegmental nerve

, inclusive hindgut primordium

, sensory neuron

, peripheral nervous system | restricted

, longitudinal connective

, embryonic/larval spiracle | precursor

, Malpighian tubule

, neuron

, vMP2 neuron

, dMP2 neuron

, deuterocerebral neuroblast | subset

, MP1 neuron

" "viable,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,male,female,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,male sterile,visible,neuroanatomy defective,poor,fertile,recessive,wild-type,partially,cold sensitive,dominant,neurophysiology defective,learning defective,memory defective,lethal - all die before end of larval stage,some die during larval stage,uncoordinated,somatic clone" "wing,chaeta,ejaculatory duct,male genitalia,embryonic/larval corpus allatum,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,eye-antennal disc,anterior crossvein,eye,NMJ bouton | third instar larval stage,indirect flight muscle motor neuron MN5,neuromuscular junction,mechanosensory neuron,eye photoreceptor cell,cone cell,ommatidium,NMJ bouton,synapse,MP1 neuron,dMP2 neuron,vMP2 neuron,Bolwig organ,photoreceptor,postvertical bristle,RP3 motor neuron,motor neuron,neuromuscular junction | larval stage,bouton,supernumerary,lobe system of adult mushroom body,border follicle cell,synapse | ectopic,calyx of adult mushroom body,somatic clone,ocellar bristle,anterior vertical bristle,posterior vertical bristle,ocellus,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,thorax & macrochaeta | somatic clone,thorax & microchaeta | somatic clone,ganglionic branch primordium,presumptive embryonic/larval tracheal system,fascicle & mushroom body | somatic clone,synapse & aCC neuron,synapse & RP2 neuron,dorsal trunk primordium,U neuron & growth cone,photoreceptor cell R8,photoreceptor cell R7,cell non-autonomous,dorsocentral bristle,external sensory organ precursor cell,photoreceptor | embryonic stage,abdominal segmental nerve | embryonic stage,abdominal ventral muscle | embryonic stage,abdominal intersegmental nerve,synapse & abdominal 2 ventral longitudinal muscle 1,synapse & abdominal 3 ventral longitudinal muscle 1,synapse & abdominal 4 ventral longitudinal muscle 1,synapse & abdominal 5 ventral longitudinal muscle 1,synapse & abdominal 6 ventral longitudinal muscle 1,synapse & abdominal 7 ventral longitudinal muscle 1,adult neuromuscular junction,abdominal segmental nerve,adult mushroom body,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,macrochaeta,axon & eye photoreceptor cellGMR.PF,axon & laminaGMR.PF,eye photoreceptor cell & laminaGMR.PF,synapse & aCC neuroneve.RRK,synapse & RP2 neuroneve.RRK,synapse & RP2 neuronB19,synapse & aCC neuronB19,synapse & RP3 neuronB19, eve.RRK,transverse nerve,synapse | ectopicl(3)H94-H94,synapsel(3)H94-H94,RP1 motor neuron,RP5 motor neuron,synapse | ectopichow-24B,synapse | ectopicl(2)E105-E105,synapse | ectopicB185,synapse | ectopicMhc.PW,synapse | ectopicelav.PLu,ocellar nerve,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,RP2 motor neuron,neuromuscular junctionfutsch-C380,neuromuscular junctionBG487,follicle cell,trichogen cell,mushroom body beta-lobe" DRSC17309 EK 0.022361657 -0.924260746 -1.008634496 1.811476752 -0.397387001 -1.998957551 FBgn0015664 Dref DNA replication-related element factor http://flybase.net/reports/FBgn0015664.html FBgn0010077 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0005509=calcium ion binding, 0000976=transcription regulatory region sequence-specific DNA binding, 0003677=DNA binding, 0001075=RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" "0010628=positive regulation of gene expression, 0006264=mitochondrial DNA replication, 0051900=regulation of mitochondrial depolarization, 0042981=regulation of apoptotic process, 0022416=chaeta development, 0006260=DNA replication, 0048813=dendrite morphogenesis, 2000495=regulation of cell proliferation involved in compound eye morphogenesis, 0007052=mitotic spindle organization, 0045035=sensory organ precursor cell division, 0022008=neurogenesis, 0001745=compound eye morphogenesis, 0006366=transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0051726=regulation of cell cycle, 0006357=regulation of transcription from RNA polymerase II promoter, 0046777=protein autophosphorylation, 0042023=DNA endoreduplication, 0045893=positive regulation of transcription, DNA-templated, 2000278=regulation of DNA biosynthetic process, 0006468=protein phosphorylation" "0005667=transcription factor complex, 0005700=polytene chromosome, 0005634=nucleus" "CG5838, DNA, DRE-binding factor, Dmel_DREF, p80/DREF, DRE (DNA replication-related element) binding factor, DNA replication-related element binding factor, DmDREF, dDREF, DNA replication-related element-binding factor, p80, replication-related element-binding factor, DNA-replication-related element factor, dref, DREF" "IPR003656=Zinc finger, BED-type, IPR012337=Ribonuclease H-like domain" CG5838 16-Dec-15 2015_12 embryonic stage -- adult stage "viable,visible,lethal,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,endomitotic cell cycle defective,neuroanatomy defective,fertile,increased cell death,mitotic cell cycle defective" "photoreceptor cell,pigment cell,eye,wing,wing vein L5,melanotic mass,wing margin bristle,somatic clone,macrochaeta,posterior scutellar bristle,anterior scutellar bristle,posterior dorsocentral bristle,anterior dorsocentral bristle,posterior notopleural bristle,presutural bristle,external sensory organ precursor cell,trichogen cell,tormogen cell,nucleus-109-68,nucleolus-109-68,microchaeta,adult thorax,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,embryonic/larval salivary gland | embryonic stage,eye disc,ommatidium,interommatidial bristle,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,scutellar bristle,ectopic,posterior compartment,wing disc,distal,dorsal,wing margin,embryonic/larval neuroblast,ganglion mother cell,ventral multidendritic neuron vdaB" DRSC03319 E 0.200008925 -0.383619684 -0.603067841 -4.339691553 -0.764175801 0.112028007 FBgn0000576 ems empty spiracles http://flybase.net/reports/FBgn0000576.html FBgn0000145 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0001158=enhancer sequence-specific DNA binding" "0014019=neuroblast development, 0035284=brain segmentation, 0035277=spiracle morphogenesis, open tracheal system, 0007419=ventral cord development, 0007383=specification of segmental identity, antennal segment, 0007424=open tracheal system development, 0042305=specification of segmental identity, mandibular segment, 0035288=anterior head segmentation, 0007389=pattern specification process, 0048813=dendrite morphogenesis, 0001700=embryonic development via the syncytial blastoderm, 0006355=regulation of transcription, DNA-templated, 0007409=axonogenesis, 0010468=regulation of gene expression, 0007420=brain development" 0005634=nucleus "empty-spiracle, Ems, EMS, antenna, Empty Spiracles, CG2988, E4, W13, empty-spiracles, ant, Empty spiracles" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG2988 16-Dec-15 2015_12 WBGene00000449(ceh-27) "ENSXETG00000021030(gsh2),ENSXETG00000011784(GSX1)" ENSMUSG00000024986(Hhex) "ENSG00000135638(EMX1),ENSG00000170370(EMX2)" " embryonic stage | stage 13 , embryonic stage | stage 6,7 , embryonic stage , embryonic stage | stage >=8 , embryonic stage | stage 4 , embryonic stage | stage >=7 , embryonic stage | stage >=9 , embryonic stage | stage 14 , embryonic stage--pupal stage , embryonic stage -- adult stage , embryonic stage | stage 12 , embryonic stage | stage 5 " " embryonic central nervous system | lateral

, cephalic furrow

, antenno-maxillary complex

,

segment polarity , organism | 70-90% egg length

, antennal segment

, embryonic/larval posterior spiracle

, mandibular segment

, intercalary segment

, subesophageal ganglion

, procephalic segment

, cephalic furrow | anterior to

, larval optic lobe | primordium

, organism | 70-80% egg length

" " embryonic stage | blastoderm , embryonic stage | stage 9-11 , embryonic stage " " head

, deuterocerebral neuroblast | subset

, protocerebral neuroblast | subset

, tritocerebral neuroblast | subset

, neuroblast

, ectoderm

, filzkorper

{ - bcd- } , procephalic neurogenic region | restricted

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,increased cell death,somatic clone,neuroanatomy defective,viable" "embryonic head,filzkorper,embryonic/larval antennal segment sensillum,central nervous system,cephalopharyngeal skeleton,embryonic mandibular segment,dorsolateral papilla,ectopic,Bolwig organ,dorsomedial papilla,hypocerebral ganglion,embryonic/larval optic lobe,associated organ,mandibular segment,intercalary segment,antennal segment,ocular segment,antennal sense organ,spiracular chamber,stigmatophore,neuroblast,somatic clone,adult brain,embryonic/larval brain,neurite,cell autonomous,fascicle,antennal lobe projection neuron lPN,antennal lobe projection neuron adPN,adult antennal lobe projection neuron VA1v adPN,adult antennal lobe projection neuron VA3 adPN,adult antennal lobe projection neuron VM2 adPN,antennal lobe,local interneuron of larval antennal lobe,tracheal primordium,visceral branch primordium,dorsal branch primordium,ganglionic branch primordium,ventral nerve cord,ventral nerve cord commissure,longitudinal connective,deuterocerebral neuromere,tritocerebral neuromere,embryonic deuterocerebrum,embryonic tritocerebrum,embryonic head epidermis,vertical bridge,lateral process,dorsal bridge,embryonic/larval pharynx,maxillary lobe,cervical connective,adult antennal lobe projection neuron DL1 adPN" FBgn0004652 fru fruitless http://flybase.net/reports/FBgn0004652.html "FBgn0000728, FBgn0001076, FBgn0012048, FBgn0038623, FBgn0038624, FBgn0038625" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0044719=regulation of imaginal disc-derived wing size, 0045433=male courtship behavior, veined wing generated song production, 0007517=muscle organ development, 0060179=male mating behavior, 0046661=male sex differentiation, 0007618=mating, 0007620=copulation, 0048813=dendrite morphogenesis, 0007530=sex determination, 0016199=axon midline choice point recognition, 0007417=central nervous system development, 0016543=male courtship behavior, orientation prior to leg tapping and wing vibration, 0002118=aggressive behavior, 0007617=mating behavior, 0048047=mating behavior, sex discrimination, 0016545=male courtship behavior, veined wing vibration, 0008049=male courtship behavior, 0007275=multicellular organismal development" 0005634=nucleus "CG14307/CG33541, CG7690, CG7689, fru-satori, fty, fruC, Fru, cg7688, satori, ms(3)06411, sat, cg7689, Dmfru, Fruitless, fruitless, fruity, BtbVI, BTB-protein-VI, FRU, BTB-VI, CT22773, CG14307, CG7688" "IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR007087=Zinc finger, C2H2, IPR011333=POZ domain, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG14307 16-Dec-15 2015_12 "ENSMUSG00000050240(Hic2),ENSMUSG00000043099(Hic1)" "ENSG00000213588(ZBTB9),ENSG00000204210,ENSG00000206280,ENSG00000206207,ENSG00000169155(ZBTB43)" " larval stage | third instar , adult stage | female , adult stage | male " " ventral nerve cord

, adult head

, central nervous system | restricted

, mushroom body

, head

, optic lobe

" "neuroanatomy defective,male limited,male,female,viable,mating behavior defective,song defective,lethal,recessive,courtship behavior defective,semi-fertile,partially lethal,partially lethal - majority live,male semi-sterile,male sterile,partially,behavior defective,mating defective,male fertile,fertile,hypoactive,chemical conditional,sterile,partially lethal - majority die,heat sensitive,lethal - all die during pupal stage,lethal - all die before end of pupal stage,some die during pupal stage,dominant,female semi-fertile,female fertile,lethal - all die before end of prepupal stage,some die during prepupal stage,conditional,size defective" "subesophageal ganglion neuron,male limited,prothoracic leg taste bristle chemosensory neuron,male,female,adult fruitless aDT-b (male) neuron,adult fruitless aSP4 neuron,adult fruitless vPR6 neuron,adult fruitless vAB3 (male) neuron,male abdominal 5 muscle,male accessory gland,vas deferens,serotonergic neuron,adult fruitless pMP-e (female) neuron,ectopic,wing,joint,anterior scutellar bristle,sternopleural bristle,tibia,macrochaeta,adult abdomen & motor neuron,adult abdomen & motor neuronfruw24),adult female posterior abdominal ganglion neuron,adult male posterior abdominal ganglion neuron,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1,antennal lobe glomerulus VL2,longitudinal connective,aCC neuron,presumptive embryonic/larval central nervous system,adult fruitless aDT-b (female) neuron,adult fruitless vAB3 (female) neuron,adult fruitless vPR1 neuron,adult fruitless aSP-b (female) neuron,adult fruitless aSP-a (female) neuron,adult fruitless pIP10 neuron,adult fruitless dPR1 neuron,adult brain,dMP2 neuron,vMP2 neuron,embryonic/larval glial cell,adult fruitless aSP-b (male) neuron,adult fruitless aSP-a (male) neuron,adult brain & neuron | medial | male,eye,posterior" FBgn0027053 CSN5 COP9 signalosome subunit 5 http://flybase.net/reports/FBgn0027053.html "FBgn0016027, FBgn0024551" protein_coding_gene "0005515=protein binding, 0019784=NEDD8-specific protease activity" "0045787=positive regulation of cell cycle, 0007275=multicellular organismal development, 0036099=female germ-line stem cell maintenance, 0035204=negative regulation of lamellocyte differentiation, 0001751=compound eye photoreceptor cell differentiation, 0007095=mitotic G2 DNA damage checkpoint, 0007310=oocyte dorsal/ventral axis specification, 0007409=axonogenesis, 0048140=male germ-line cyst encapsulation, 0050821=protein stabilization, 0008347=glial cell migration, 0010388=cullin deneddylation, 2000600=positive regulation of cyclin catabolic process, 0035207=negative regulation of hemocyte proliferation, 0032435=negative regulation of proteasomal ubiquitin-dependent protein catabolic process, 0048142=germarium-derived cystoblast division, 0048477=oogenesis, 0007281=germ cell development, 0007314=oocyte anterior/posterior axis specification" "0008180=COP9 signalosome, 0005737=cytoplasm, 0034399=nuclear periphery" "Jab1, DCH5, BcDNA.LD14392, JadBp, l(3)L4032, BcDNA:LD14392, quo, COP9 complex homolog subunit 5, csn5, JAB1, jab1/csn5, JAB1/CSN5, COP9 complex subunit 5, dch5, Jun activation domain binding protein, l(3)M203, Dch5, CH5, Csn5, l(3)89Cf, JUN activation domain-binding protein-1, CG14884, Q9XZ58, CSN-5, Drosophila COP9 signalosome homolog 5" IPR000555=JAB1/MPN/MOV34 metalloenzyme domain CG14884 16-Dec-15 2015_12 ENSDARG00000057624(cops5) WBGene00000817(csn-5) ENSXETG00000023263(cops5) ENSMUSG00000025917(Cops5) ENSG00000121022(COPS5) "lethal,recessive,heat sensitive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage,partially lethal - majority die,size defective,developmental rate defective,female sterile,germline clone,chemical sensitive,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,female sterile germline-dependent,wild-type" "larva,pupa,germarium,nurse cell spectrosome,germline clone,dorsal appendage,chorion | germline clone,egg,pole cell,nurse cell,trichogen cell,supernumerary,scutellum,wing,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,lamina anlage glial cell,somatic clone,ovary,photoreceptor cell R2 & axonRK6-3),photoreceptor cell R3 & axonRK6-3),photoreceptor cell R4 & axonRK6-3),photoreceptor cell R5 & axonRK6-3),melanotic mass,eye,wing vein,ectopic,cystocyte,female germline stem cell,nurse cell fusome,embryonic/larval optic neuropil" DRSC22381 K 0.719248814 0.001400095 0.895464974 0.634157517 0.303823688 1.830605397 FBgn0001228 Hsp67Bb Heat shock gene 67Bb http://flybase.net/reports/FBgn0001228.html "FBgn0044743, FBgn0052041, FBgn0061943, FBtr0076448, FBpp0076176, FBtr0076449, FBpp0076177, FBtr0076450, FBpp0076178, FBtr0076451, FBpp0076179" protein_coding_gene 0009408=response to heat "gene-2, gene 2, Hsp-G2, gene4, heatshock protein 67Bb, Hspg2, anon-WO0118547.50, gene2, hsp67B, hsp67Bb, Gene 2, CG32041, anon-WO0140519.138, small hsp locus 67B, CG4456, EP(3)3247, heat shock gene 2" IPR001763=Rhodanese-like domain CG4456 16-Dec-15 2015_12 ENSDARG00000071567(LOC563265) "YOR286W(RDL2),YOR285W(RDL1)" ENSMUSG00000028251(2610029I01Rik) ENSG00000215845(TSTD1) " larval stage | second instar , larval stage | third instar , adult stage | male , pupal stage | early , adult stage , spermatogenesis && adult stage , embryonic stage | >=7 hr , larval stage | first instar , pupal stage " testis

"viable,fertile" DRSC11187 I 1.590762874 0.13571716 0.238029619 0.612296906 -0.280035029 -0.352874165 FBgn0053872 His2B:CG33872 His2B:CG33872 http://flybase.net/reports/FBgn0053872.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33872 "IPR000558=Histone H2B, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33872 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" DRSC21265 IEK -3.316197339 -3.688847288 -3.887860139 -6.859443014 -2.278549339 -2.413391746 FBgn0015903 apt apontic http://flybase.net/reports/FBgn0015903.html "FBgn0010526, FBgn0010619, FBgn0010654, FBgn0016073, FBgn0021909, FBgn0023031" protein_coding_gene "0001158=enhancer sequence-specific DNA binding, 0003729=mRNA binding, 0005515=protein binding, 0043565=sequence-specific DNA binding, 0003730=mRNA 3'-UTR binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007507=heart development, 0007417=central nervous system development, 0010468=regulation of gene expression, 0046011=regulation of oskar mRNA translation, 0007274=neuromuscular synaptic transmission, 0007427=epithelial cell migration, open tracheal system, 0007298=border follicle cell migration, 0007428=primary branching, open tracheal system, 0007319=negative regulation of oskar mRNA translation, 0046426=negative regulation of JAK-STAT cascade, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048149=behavioral response to ethanol, 0006357=regulation of transcription from RNA polymerase II promoter, 0035289=posterior head segmentation, 0007424=open tracheal system development" "0005737=cytoplasm, 0005634=nucleus" "Apontic, Trachea defective, l(2)06369, Apt, 3041, l(2)03041, tdf, l(2)k11531, trachea defective, CG5393, TDF, TDF/APT, tracheal defective, unnamed, l(2)09049, l(2)59Ea, tracheae defective" "IPR001005=SANT/Myb domain, IPR028002=Myb/SANT-like DNA-binding domain" CG5393 16-Dec-15 2015_12 " embryonic stage | stage >=11 , embryonic stage | stage >=9 , embryonic stage | stage 11 , embryonic stage | cellular blastoderm , embryonic stage | 0-18 hr , embryonic stage | stage 12 , embryonic stage | stage 9-10 , adult stage && oogenesis stage , embryonic stage | stage 9-11 , embryonic stage , egg stage | unfertilized egg , embryonic stage | syncytial blastoderm , embryonic stage | stage 14-17 , embryonic stage | stage 11-17 " " embryonic/larval tracheal system

,

segmentally repeated , dorsal ridge

, tracheal primordium

, amnioserosa | vicinity of

segmentally repeated , ventral midline

segmentally repeated , dorsal vessel primordium

, labral segment

, embryonic gnathal segment | ventral

, nurse cell

, cardioblast

, tracheal pit

segmentally repeated , embryonic head

, labial segment | restricted

, oocyte

, ventral nervous system

, unfertilized egg

, follicle cell

, embryonic ocular segment | dorsal

, embryonic mandibular segment | restricted

,

ubiquitous , embryonic/larval dorsal vessel

, embryonic maxillary segment | restricted

, embryonic central nervous system

" " embryonic stage | stage >=4 , adult stage && oogenesis stage , embryonic stage | early , embryonic stage | stage 14-17 , embryonic stage | stage 11 , embryonic stage | stage >=11 " " organism

, follicle cell

, embryonic/larval tracheal system

, oocyte

, embryonic central nervous system

, nurse cell

, tracheal primordium

, embryonic/larval dorsal vessel

, embryonic head

" "lethal,chemical resistant,viable,recessive,neuroanatomy defective,fertile,visible,fully,rescuable maternal effect,tumorigenic,partially lethal - majority die,neurophysiology defective,some die during embryonic stage,cell migration defective,somatic clone,dominant,wild-type,lethal - all die before end of embryonic stage,some die during pupal stage" "anterior fascicle & synapse,synapse,intersegmental nerve,anterior fascicle & synapse | supernumerary,embryonic maxillary segment,embryonic mandibular segment,dorsocentral bristle,scutellar bristle,macrochaeta,ectopic,trichogen cell,embryonic/larval trachea,embryonic/first instar larval cuticle,embryonic head,wing,posterior compartment,embryonic/larval heart,neuromuscular junction,embryonic/larval neuromuscular junction,ventral nerve cord,egg chamber,germline clone,oocyte,central nervous system,dorsal closure embryo,presumptive embryonic/larval tracheal system,presumptive embryonic/larval central nervous system,somatic clone,border follicle cell,hypostomal sclerite,lateral process,dorsal pouch,dorsal bridge,heart primordium,egg chamber | oogenesis stage S10,border follicle cell | oogenesis stage S10,mesothoracic tergum" FBgn0261434 hkb huckebein http://flybase.net/reports/FBgn0261434.html "FBgn0086720, FBgn0001204, FBan0009768, FBgn0014111" protein_coding_gene "0008134=transcription factor binding, 0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0010001=glial cell differentiation, 0007431=salivary gland development, 0007417=central nervous system development, 0061024=membrane organization, 0008293=torso signaling pathway, 0046331=lateral inhibition, 0001708=cell fate specification, 0001706=endoderm formation, 0008354=germ cell migration, 0007400=neuroblast fate determination, 0007374=posterior midgut invagination, 0006351=transcription, DNA-templated, 0009948=anterior/posterior axis specification, 0007419=ventral cord development, 0007362=terminal region determination, 0007375=anterior midgut invagination, 0007492=endoderm development, 0007435=salivary gland morphogenesis, 0007369=gastrulation, 0007499=ectoderm and mesoderm interaction, 0035239=tube morphogenesis" 0005634=nucleus "gurt, gurtelchen, HKB, anon-82B3, 5953, Huckebein, CG9768, hucklebein, huckbein, Hkb" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG9768 16-Dec-15 2015_12 "YPR015C(),YPR013C()" ENSMUSG00000030087(Klf15) "ENSG00000129911(KLF16),ENSG00000174595(KLF14),ENSG00000169926(KLF13),ENSG00000109787(KLF3),ENSG00000105610(KLF1),ENSG00000184937(WT1),ENSG00000163884(KLF15),ENSG00000189120(SP6)" " embryonic stage | stage 9-10 , embryonic stage | gastrula , embryonic stage | late , embryonic stage | stage 9-11 , embryonic stage | stage 4 , embryonic stage | stage 6-8 " " procephalic neurogenic region && embryonic ocular segment | restricted

, embryonic central nervous system | precursor | segmentally repeated pattern

, adult salivary gland primordium

posterior , tritocerebral neuroblast | subset

,

90-100% egg length , protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic intercalary segment | restricted & anterior

, deuterocerebral neuroblast | subset

, ventral neurogenic region | restricted

, organism | 0-20% egg length

,

terminal , organism | 0-10% egg length

, organism | 80-100% egg length

, adult salivary gland primordium

anterior , procephalic neurogenic region && embryonic antennal segment | restricted

" " embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | blastoderm , embryonic stage | stage 9 " " intermediate ventral neurectoderm | row 1/2

, neuroblast NB1-1

, organism | 90-100% egg length

, neuroblast NB4-2

, neuroblast NB5-4

, neuroblast NB7-3

, organism | 0-10% egg length

, neuroblast NB2-2

" FBgn0024189 sns sticks and stones http://flybase.net/reports/FBgn0024189.html "FBgn0026614, FBgn0033331, FBgn0033332, FBgn0033333, FBgn0033334, FBgn0033335, FBgn0033336, FBgn0040776, FBgn0042193, FBgn0053141" protein_coding_gene 0005515=protein binding "0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0061321=garland nephrocyte differentiation, 0036059=nephrocyte diaphragm assembly, 0007286=spermatid development, 0097206=nephrocyte filtration, 0007155=cell adhesion, 0007520=myoblast fusion, 0030036=actin cytoskeleton organization, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0001745=compound eye morphogenesis, 0007523=larval visceral muscle development" "0005917=nephrocyte diaphragm, 0005886=plasma membrane" "rost, sticks-and-stones, Sticks-and-Stones, CG13752, CG13754, Sticks and stone, SNS, CT33230, CG18464, Sticks and Stones, sns20, Sticks-and-stones, CG8278, CG13753, Sticks and stones, CG13755, CT33232, CG2385, CG12495, Sns, CG33141, unnamed, 43-49, stick-and-stones" "IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013162=CD80-like, immunoglobulin C2-set, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III" CG33141 16-Dec-15 2015_12 ENSDARG00000060758(nphs1l) WBGene00007750(syg-2) ENSXETG00000017513(NPHS1) ENSMUSG00000006649(Nphs1) ENSG00000161270(NPHS1) " embryonic stage | stage 17 , embryonic stage | stage 11-17 , embryonic stage | stage 11-14 , embryonic stage | stage 11-13 " " muscle attachment site

, embryonic/larval somatic muscle

, somatic mesoderm

, visceral mesoderm

" " embryonic stage | stage 11-14 , embryonic stage | stage 11-17 , embryonic stage | stage 11-13 " " somatic mesoderm

, embryonic/larval somatic muscle

, visceral mesoderm

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,male fertile,lethal,cell adhesion defective,somatic clone,viable,visible,male sterile" "somatic muscle,myoblast,muscle founder cell,embryonic/larval garland cell,wing margin,wing hair,embryonic/larval pericardial cell,nephrocyte diaphragmDot.PK,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,embryonic/larval muscle system,circular visceral muscle fiber,longitudinal muscle,midgut constriction 1,embryonic myoblast,embryonic/larval somatic muscle,embryonic/larval visceral muscle,circular visceral muscle primordium,embryonic garland cell,eye,somatic clone,ommatidium,inter-ommatidial cell,inter-ommatidial precursor cell,interommatidial bristle,wing,trichogen cell,mesothoracic tergum,spermatid cyst,seminal vesicle,embryonic/larval brain" DRSC07687 I -1.872664127 1.327758582 1.055115903 -0.382358116 0.664053069 -0.441701653 FBgn0000578 ena enabled http://flybase.net/reports/FBgn0000578.html "FBgn0010503, FBgn0063438" protein_coding_gene "0005515=protein binding, 0003779=actin binding, 0017124=SH3 domain binding" "0030036=actin cytoskeleton organization, 0003382=epithelial cell morphogenesis, 0008064=regulation of actin polymerization or depolymerization, 0051491=positive regulation of filopodium assembly, 0031346=positive regulation of cell projection organization, 0007390=germ-band shortening, 0030335=positive regulation of cell migration, 0008360=regulation of cell shape, 0045886=negative regulation of synaptic growth at neuromuscular junction, 1990255=subsynaptic reticulum organization, 0008258=head involution, 0032956=regulation of actin cytoskeleton organization, 0048749=compound eye development, 0007010=cytoskeleton organization, 0007391=dorsal closure, 0051489=regulation of filopodium assembly, 0007303=cytoplasmic transport, nurse cell to oocyte, 0060288=formation of a compartment boundary, 0007409=axonogenesis, 0007298=border follicle cell migration, 0007411=axon guidance, 0007015=actin filament organization, 0007396=suture of dorsal opening, 0035262=gonad morphogenesis, 0048813=dendrite morphogenesis, 0010591=regulation of lamellipodium assembly" "0071212=subsynaptic reticulum, 0030425=dendrite, 0030424=axon, 0005912=adherens junction, 0032433=filopodium tip, 0031252=cell leading edge, 0030027=lamellipodium, 0005911=cell-cell junction" "enb, Ena, CG15112, Enb, ENA/VASP, Vasp, l(2)02029, VASP, Enabled" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR014885=VASP tetramerisation, IPR000697=WH1/EVH1 domain, IPR000156=Ran binding domain" CG15112 16-Dec-15 2015_12 "ENSDARG00000035650(evla),ENSDARG00000031086(evlb),ENSDARG00000032049(enah),ENSDARG00000017105(vasp),ENSDARG00000059110(zgc:162320)" ENSXETG00000002529(EVL) " embryonic stage | stage 10,11 , oogenesis stage , larval stage , embryonic stage , embryonic stage | stage 8-11 , embryonic stage | stage 12-14 , embryonic stage | stage 15,16 , embryonic stage | stage 15-17 " " endoderm

, follicle cell

, photoreceptor cell

, rhabdomere

, embryonic central nervous system | restricted

, embryonic central nervous system | presumptive

, ventral nerve cord commissure

, embryonic hindgut

, embryonic leading edge cell

, longitudinal connective

, neuron

, segment | segment boundary

, adepithelial cell

, imaginal disc | restricted

" "lethal,recessive,partially lethal - majority die,neuroanatomy defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,majority die during embryonic stage,cell shape defective,cell migration defective,size defective,viable,visible" "lamellipodium,filopodium,gonad,germline cell,gonadal sheath proper primordium,filopodium & embryonic leading edge cellen-e16E,filopodium | ectopicen-e16E,filopodiumen-e16E,border follicle cell,macrochaeta,central nervous system,commissure,stage 14 embryo,longitudinal connective,intersegmental nerve,adult mushroom body,somatic clone,embryonic/first instar larval cuticle,maternal effect,embryonic head epidermis,embryonic dorsal epidermis,actin filament & egg chamber | germ-line clone,class IV dendritic arborizing neuron,axon,peripheral nervous system,presumptive embryonic/larval central nervous system,intersegmental nerve branch ISNb of A1-7,follicle cell & actin filament | somatic clone,embryonic head,egg,germline clone,embryo,embryonic leading edge cell,ventral head epidermis,dendrite | dorsal | embryonic stage,RP neuron,follicle cell & actin filamentCY2,nurse cell & actin filamentmat.ë±Tub67C.THsimVP16,wing,NMJ bouton | third instar larval stage,subsynaptic reticulum | third instar larval stagehow-24B,embryonic/larval neuromuscular junction,NMJ bouton,trichogen cell,dorsal-ventral compartment boundary of the wing | third instar larval stage" DRSC07610 I 0.608180627 -2.102451686 -0.549969558 -0.070331999 0.301057218 1.457031514 FBgn0003944 Ubx Ultrabithorax http://flybase.net/reports/FBgn0003944.html FBgn0024276 protein_coding_gene "0003677=DNA binding, 0019904=protein domain specific binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0005515=protein binding" "0010092=specification of organ identity, 0001709=cell fate determination, 0045570=regulation of imaginal disc growth, 0007385=specification of segmental identity, abdomen, 0006357=regulation of transcription from RNA polymerase II promoter, 0007482=haltere development, 0007424=open tracheal system development, 0001706=endoderm formation, 0042694=muscle cell fate specification, 0060969=negative regulation of gene silencing, 0007501=mesodermal cell fate specification, 0048636=positive regulation of muscle organ development, 0061327=anterior Malpighian tubule development, 0035052=dorsal vessel aortic cell fate commitment, 0007507=heart development, 0007480=imaginal disc-derived leg morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007494=midgut development, 0006355=regulation of transcription, DNA-templated, 0042659=regulation of cell fate specification, 0007384=specification of segmental identity, thorax, 0007525=somatic muscle development" 0005634=nucleus "Ultabithorax, Ultarbithorax, bithorax, bx[D], Contrabithorax, Ultraabdominal, DmUbx, Hm, abx, Uab, l(3)89Eb, Ubx1b, Bxl, pbx, bxd[D], bx, DUbx, UBx, Dm Ubx, bxd, Cbx, postbithorax, Haltere mimic, BX-C, anterobithorax, bithorax complex, CG10388, ubx, bithoraxoid, UBX, ultrabithorax, bxl" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001827=Homeobox protein, antennapedia type, conserved site, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain" CG10388 16-Dec-15 2015_12 "ENSDARG00000059255(evx2),ENSDARG00000005628" WBGene00003912(pal-1) " embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 1-17 , embryonic stage | stage 11-17 , embryonic stage | late " " parasegment 6 &&of embryonic central nervous system

, parasegment 5--13

, somatic mesoderm

, visceral mesoderm

, embryonic central nervous system

" " embryonic stage | mid-late , embryonic stage , embryonic stage | late , embryonic stage | stage 15-16 , larval stage , embryonic stage | stage 13-14 , embryonic stage | stage 11,13 " " parasegment 7 visceral mesoderm

{ + abd-AM1 } , visceral mesoderm &&of parasegment 7--12 <

, visceral mesoderm

{ 0 en* } , parasegment 7 visceral mesoderm

{ $ ftz* } , visceral mesoderm

{ 0 odd* } , visceral mesoderm

{ $ opa*/prd* } , visceral mesoderm

{ 0 Kr* } , visceral mesoderm

{ 0 odd*/eve* } , cardioblast && embryonic pericardial cell &&of embryonic abdominal segment 2--5

, parasegment 5--13 &&of embryonic ventral nervous system | segmentally repeated

, larval fat body | central

, visceral mesoderm

{ $ eve4 } , visceral mesoderm

, visceral mesoderm &&of embryonic/larval midgut &&ofparasegment 7

, visceral mesoderm

{ $ kni* } , visceral mesoderm

{ 0 opa* } , visceral mesoderm

{ - ftz*/prd* } , parasegment 6 visceral mesoderm

{ 0 dpphs.PT } , visceral mesoderm

{ 0 wg* } , visceral mesoderm

{ $ hb* } , visceral mesoderm

{ 0 prd* } , visceral mesoderm

{ 0 h* } , visceral mesoderm

{ - eve3 } , visceral mesoderm

{ 0 run* } , embryonic dorsal vessel | central

" "visible,dominant,homeotic,somatic clone,lethal,recessive,heat sensitive,wild-type,decreased cell size,cell autonomous,neuroanatomy defective,viable,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,fertile,reduced,partially lethal - majority die,male" "ventral thoracic disc,spiracle,embryonic dorsal vessel,abdominal ventral denticle belt,abdominal tergite 1,Kolbchen,tracheal pit,abdominal segment,haltere,metathoracic segment,Keilin's organ,wing,embryonic thoracic segment,mesothoracic tibial apical bristle,mesothoracic tibial preapical bristle,-109-68,midgut constriction,metathoracic leg,adult metathoracic segment,katepimeron,mesothoracic tergum,metathoracic metatarsus,metathoracic femur,metathoracic tarsal bristle,capitellum,haltere sensillum,dorsal metathorax,ventral metathorax,mesothoracic leg,prothoracic leg,sternopleural bristle,metathoracic tibial preapical bristle,wing margin bristle,mesothoracic intersegmental nerve,metathoracic laterotergite,adult mesothoracic segment,tracheal metamere 3,tracheal metamere 2,direct flight muscle,tergosternal muscle,coxal tergal remotor muscle,lateral oblique dorsal muscle,dorsal medial muscle,myoblast,leg,giant fiber neuron,mesothoracic extracoxal depressor muscle 66,haltere disc,mesothoracic segmental nerve,wing hair,macrochaeta,histoblast nest,embryonic head,presumptive embryonic/larval peripheral nervous system,antenna,eye,external sensory organ,abdominal 1 lateral monoscolopidial chordotonal organ lch1,mesothoracic dorsal triscolopidial chordotonal organ dch3,,prothoracic segment,mesothoracic segment,parasegment 1,parasegment 2,parasegment 3,parasegment 4,parasegment 5,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,mesothoracic femur,prothoracic femur,metathoracic tracheal pit,mesothoracic tracheal pit,head,trichome of the posterior wing margin,wing cell,wing sensillum,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,larval head,embryonic mandibular segment,embryonic maxillary segment,embryonic labial segment,eye-antennal disc,thorax,embryonic/larval epidermis,thoracic segment,mesothoracic laterotergite,capitella sensillum trichodeum,metathoracic segmental nerve,metathoracic intersegmental nerve,embryonic epidermis,alula,aorta primordium,wing disc,abdominal ventral acute muscle,embryonic/larval lymph gland,embryonic visceral muscle,embryonic anterior Malpighian tubule,multidendritic neuron,adult prothoracic segment,posterior vertical bristle,postvertical bristle,chordotonal organ,abdominal dorsal transverse muscle,abdominal 1 lateral transverse muscle,abdominal 2 lateral transverse muscle,presumptive embryonic/larval central nervous system,metathoracic pleurum,mesothoracic pleurum,embryonic head segment,T1 beard,gastric caecum,dorsal acute muscle,scutum,embryonic/first instar larval cuticle,indirect flight muscle,mesothoracic dorsal acute muscle 3,metathoracic dorsal acute muscle,cardioblast,embryonic/larval ostia,embryonic/larval dorsal vessel,gonadal sheath proper primordium,larval neuromere,arista,pretarsus,embryonic tritocerebrum,adult head,embryonic/larval pericardial cell,eye disc,lymph gland primordium,embryonic/larval posterior spiracle,abdominal 11 anal tuft,wing blade,wing margin,cephalopharyngeal skeleton,pharynx,prothoracic ventral intersegmental muscle,T1 beard,dorsal closure embryo,embryonic brain,ppk.PG,skeletal muscle of thorax" FBgn0003513 ss spineless http://flybase.net/reports/FBgn0003513.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity" "0007613=memory, 0006366=transcription from RNA polymerase II promoter, 0048800=antennal morphogenesis, 0006355=regulation of transcription, DNA-templated, 0010092=specification of organ identity, 0036011=imaginal disc-derived leg segmentation, 0008049=male courtship behavior, 0045676=regulation of R7 cell differentiation, 0007469=antennal development, 0048814=regulation of dendrite morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005829=cytosol" "aristapedia, Ss, CG6993, Spineless, ssa, spineless-aristapedia, AhR, SS, AHR" "IPR013655=PAS fold-3, IPR001610=PAC motif, IPR013767=PAS fold, IPR000014=PAS domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG6993 16-Dec-15 2015_12 "ENSDARG00000023537(ahr1b),ENSDARG00000021833(ahr2),ENSDARG00000020046(ahr1a)" WBGene00000096(ahr-1) ENSXETG00000022784(Q4QY29_XENTR) ENSG00000106546(AHR) " embryonic stage | stage >8 , pupal stage , embryonic stage , larval stage | third instar , larval stage | second instar , embryonic stage | stage 8 " " embryonic labial segment

, sensory mother cell

, embryonic antennal segment

, trichogen cell

, dorsal metathoracic disc

, tarsus | presumptive

, eye disc

, antennal disc

, leg | anlagen

, dorsal mesothoracic disc | restricted

, labial disc

, embryonic mandibular segment

, embryonic maxillary segment

, embryonic peripheral nervous system

, cephalic furrow | anterior to

, genital disc

, morphogenetic furrow

, ventral thoracic disc

, maxillary palpus | anlagen

" "visible,homeotic,viable,fertile,somatic clone,recessive,lethal,gravitaxis defective,reduced,sterile,dominant,flightless,courtship behavior defective,memory defective,male sterile,female semi-sterile,neuroanatomy defective,behavior defective,increased cell death,cell non-autonomous,cell autonomous,heat sensitive" "dorsomedial papilla,dendrite & dorsal multidendritic neuron ddaE,macrochaeta,tarsal segment,labial sensillum,somatic clone,bract,arista,proximal,third segment of antenna,distal,antenna,antennal segment,sex comb,ectopic,joint,metatarsus,second segment of antenna,fourth segment of antenna,fifth segment of antenna,antennal disc,leg,tarsal segment 2,tarsal segment 3,tarsal segment 4,ventral thoracic disc,pretarsus,microchaeta,wing,mesothoracic tarsal segment,vertical bristle,posterior vertical bristle,scutellar bristle,prothoracic tarsal segment,metathoracic tarsal segment,unguis,cold sensitive,maxillary palpus,antennal sense organ,dendrite & dorsal multidendritic neuron ddaE | somatic clone,dendrite & dorsal multidendritic neuron ddaD | somatic clone,dendrite & dorsal multidendritic neuron ddaB | somatic clone,dendrite & dorsal multidendritic neuron ddaC | somatic clone,dendrite & lateral multidendritic neuron ldaB | somatic clone,dendrite & dorsal multidendritic neuron ddaF | somatic clone,pale ommatidium,yellow ommatidium,photoreceptor cell R7 of yellow ommatidium,photoreceptor cell R7 of pale ommatidium,eye-antennal disc,chaeta,thorax,mesothoracic leg,denticle belt,medial,tracheal branch primordium,rostral membrane,femur,anterior compartment,tibia,tergite,wing margin,wing disc,cell autonomous,dendrite & tracheal innervating neuron477,dendrite & dorsal multidendritic neuron ddaCppk.PG,eye,ommatidium,eye photoreceptor cell,heat sensitive,trichogen cell,mesothoracic tergum" FBgn0005672 spi spitz http://flybase.net/reports/FBgn0005672.html "FBgn0002048, FBgn0003474, FBgn0010472, FBgn0010690, FBgn0062206" protein_coding_gene "0005154=epidermal growth factor receptor binding, 0008317=gurken receptor binding" "0043066=negative regulation of apoptotic process, 0048865=stem cell fate commitment, 0045470=R8 cell-mediated photoreceptor organization, 0007438=oenocyte development, 0007424=open tracheal system development, 0048149=behavioral response to ethanol, 0035277=spiracle morphogenesis, open tracheal system, 0007421=stomatogastric nervous system development, 0022008=neurogenesis, 0008284=positive regulation of cell proliferation, 0008355=olfactory learning, 0007173=epidermal growth factor receptor signaling pathway, 0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0007298=border follicle cell migration, 0000086=G2/M transition of mitotic cell cycle, 0007476=imaginal disc-derived wing morphogenesis, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0035225=determination of genital disc primordium, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0050769=positive regulation of neurogenesis, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0007432=salivary gland boundary specification, 0007422=peripheral nervous system development, 0016330=second mitotic wave involved in compound eye morphogenesis, 0003015=heart process" "0005886=plasma membrane, 0005794=Golgi apparatus, 0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005576=extracellular region" "s-spi, sSpi, CG10334, anon-WO0118547.158, Spitz, Spi, EP(2)2378, l(2)01068, l(2)37Fa, CT29014, l(2)s3547, epidermal growth factor protein" "IPR013032=EGF-like, conserved site, IPR000742=EGF-like domain" CG10334 16-Dec-15 2015_12 embryonic stage " peripheral nervous system

, ventral midline

, mesoderm

" embryonic stage " ventral midline

, mesoderm

" "viable,fertile,neuroanatomy defective,poor,visible,recessive,lethal,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,learning defective,RU486 conditional,heat sensitive,wild-type,increased cell death,somatic clone,cell death defective,increased cell number,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage,homeotic,male,female,decreased cell number,chemical resistant" "anterior commissure,posterior commissure,midline glial cell,,ventral oblique muscle,embryonic/larval somatic muscle,ventral longitudinal muscle,abdominal dorsal acute muscle,optic lobe,Bolwig organ,embryonic stomatogastric nervous system,embryonic/larval brain,hypocerebral ganglion,embryonic/larval recurrent nerve,epidermis,peripheral nervous system,eye,rhabdomere,egg,photoreceptor,macrochaeta,ventral nerve cord,embryonic/larval ganglionic branch,embryonic/first instar larval cuticle,wing,embryonic/larval salivary gland,intersegmental nerve,midgut,bract,lamellocyte,photoreceptor cell,cone cell,pigment cell,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,abdominal ventral monoscolopidial chordotonal organ,abdominal lateral pentascolopidial chordotonal organ,embryonic ventral nervous system,Keilin's organ,anal pad,cephalopharyngeal skeleton,Malpighian tubule,embryonic anterior Malpighian tubule,genital disc primordium,tracheal primordium,presumptive embryonic/larval tracheal system,embryonic/larval stomatogastric nervous system,stomodeal invagination,lch5 cap attachment cell,lch5 ligament attachment cell,embryonic/larval trachea,A1-7 ventral acute muscle 2,embryonic ventral epidermis,eye disc,embryonic/larval oenocyte,midline ventral glial cell,ventral nerve cord commissure,ommatidium,dorsal neurohemal organ,embryonic/larval optic lobe,peripheral glial cell,anterior fascicle sensory neuron,posterior fascicle sensory neuron,adult salivary gland primordium,embryonic segment,lch5 neuron,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,germline stem cell,embryonic epidermis,wing disc,en-e16E,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic prothoracic segment,stigmatophore,filzkorper,trichome,neuron,hs.PB,retina,subretinal glial cell,denticle,embryonic/larval cuticle,dorsal appendage,dorsal hair,muscle founder cell |,ventral thoracic disc,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,Dll-md23,antenna,wing hair,aCC neuron,pCC neuron,mesothoracic tibial bract,border follicle cell,stomatogastric nervous system anlage,adult midgut precursor cell |,midgut interstitial cell,lamellocyte | larval stage,enterocyte,chorion,ganglion mother cell,embryonic/larval brain,adult heart" DRSC03618 E -0.281165558 0.118014637 -2.175545547 -0.08601617 0.128460281 -0.762398571 FBgn0004102 oc ocelliless http://flybase.net/reports/FBgn0004102.html "FBgn0002979, FBgn0003021" protein_coding_gene "0046982=protein heterodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0042803=protein homodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007355=anterior region determination, 0048816=ocellus morphogenesis, 0007399=nervous system development, 0042463=ocellus photoreceptor cell development, 0007417=central nervous system development, 0045871=negative regulation of rhodopsin gene expression, 0001700=embryonic development via the syncytial blastoderm, 0007389=pattern specification process, 0008056=ocellus development, 0007628=adult walking behavior, 0061541=rhabdomere morphogenesis, 0045893=positive regulation of transcription, DNA-templated, 0007420=brain development, 0045872=positive regulation of rhodopsin gene expression, 0042052=rhabdomere development, 0035288=anterior head segmentation, 0010628=positive regulation of gene expression, 0045315=positive regulation of compound eye photoreceptor development, 0007419=ventral cord development, 0046552=photoreceptor cell fate commitment, 0035284=brain segmentation, 0042051=compound eye photoreceptor development, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "Otx, ort, Oc, otd, Otd, orthodenticle, Ocelliless, l(1)8Ac, uvi, l(1)7Ff, CG12154, uvi-insensitive, orthodentical, Orthodenticle" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG12154 16-Dec-15 2015_12 "ENSDARG00000043483(otx5),ENSDARG00000011989(crx),ENSDARG00000011235(otx2),ENSDARG00000043643(otx1b),ENSDARG00000030703(otx1a)" WBGene00000457(ceh-36) "ENSXETG00000018775(BC085002.1),ENSXETG00000015687(otx2),ENSXETG00000013025(OTX1)" ENSMUSG00000007946(Phox2a) "ENSG00000165462(PHOX2A),ENSG00000109132(PHOX2B)" " embryonic stage | 5-13 hr , embryonic stage | cellular blastoderm , embryonic stage | stage 5 , embryonic stage | stage 3 , embryonic stage | stage 3-5 , embryonic stage | stage 7 , embryonic stage | stage 4 , embryonic stage | stage 6-17 , embryonic stage | stage 8 , embryonic stage " " ventral midline

,

70-90% egg length , organism | 80-100% egg length

,organism | dorsal

,

anterior , procephalic segment

, organism | 70-90% egg length

, procephalic neurogenic region | restricted

, organism | 90-100% egg length

, head mesoderm

, head

" embryonic stage | stage 9-11 " procephalic neurogenic region && embryonic intercalary segment | restricted & ventral

, tritocerebral neuroblast | subset

, procephalic neurogenic region &&of embryonic ocular segment

, protocerebral neuroblast | subset

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic head | restricted & dorsal & central

, procephalic neurogenic region && embryonic antennal segment

" "visible,viable,female sterile,lethal,recessive,locomotor behavior defective,eclosion rhythm defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,visual behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic head,embryonic segment,ganglion,ectopic,presumptive embryonic/larval central nervous system,embryonic brain,embryonic head & ganglion,ventral nerve cord,posterior,presumptive embryonic/larval peripheral nervous system,dorsomedial papilla,antennal sense organ,dorsolateral papilla,terminal organ,cephalopharyngeal skeleton,cirri,ocellus & macrochaeta,frons & macrochaeta,macrochaeta,ocellus,frons,female accessory gland,protocerebral bridge,postvertical bristle,ocellar bristle,interocellar bristle,lateral ocellus,medial ocellus,ocellus pigment granule,ocellus lens,protocerebral neuromere,embryonic protocerebral neuromere,embryonic brain & commissure,neuropil,commissure,embryonic ventral epidermis,longitudinal connective,embryonic antennal segment,posterior commissure,antennal primordium,antennal segment,growth cone,anterior commissure,midline glial cell,abdominal 1 dorsal VUM motor neuron,abdominal 2 dorsal VUM motor neuron,abdominal 3 dorsal VUM motor neuron,abdominal 4 dorsal VUM motor neuron,abdominal 5 dorsal VUM motor neuron,abdominal 6 dorsal VUM motor neuron,abdominal 7 dorsal VUM motor neuron,abdominal 1 ventral VUM motor neuron,abdominal 2 ventral VUM motor neuron,abdominal 3 ventral VUM motor neuron,abdominal 4 ventral VUM motor neuron,abdominal 5 ventral VUM motor neuron,abdominal 6 ventral VUM motor neuron,abdominal 7 ventral VUM motor neuron,abdominal 1 lateral VUM motor neuron,abdominal 2 lateral VUM motor neuron,abdominal 3 lateral VUM motor neuron,abdominal 4 lateral VUM motor neuron,abdominal 5 lateral VUM motor neuron,abdominal 6 lateral VUM motor neuron,abdominal 7 lateral VUM motor neuron,neuroblast MNB,deuterocerebral neuromere,ventral midline,abdominal neuromere,embryonic protocerebrum,embryonic central brain,pars intercerebralis,protocerebrum,female gonopod,denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,photoreceptor cell,rhabdomere,cone cell,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere R7,rhabdomere R8,rhabdomere of eye photoreceptor cell,ommatidium,photoreceptor,rhabdomereoc.1.6,embryonic/larval pharynx | embryonic stage,mouth hooks,precursor cell of the stomatogastric nervous system" FBgn0028325 l(1)G0334 lethal (1) G0334 http://flybase.net/reports/FBgn0028325.html FBgn0029721 protein_coding_gene 0004739=pyruvate dehydrogenase (acetyl-transferring) activity "0006096=glycolytic process, 0055114=oxidation-reduction process, 0006090=pyruvate metabolic process" "0005739=mitochondrion, 0045254=pyruvate dehydrogenase complex" "E1-PDH, CG7010, CG 7010, Pyruvate dehydrogenase, l (1) G0334, PDH, Pdh, pyruvate dehydrogenase, L(1)g0334, PDH complex" "IPR001017=Dehydrogenase, E1 component, IPR029061=Thiamin diphosphate-binding fold, IPR017597=Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y" CG7010 16-Dec-15 2015_12 "ENSDARG00000010555(pdha1b),ENSDARG00000012387(pdha1a)" YER178W(PDA1) WBGene00011510(T05H10.6) ENSXETG00000006212(pdha1) "ENSMUSG00000031299(Pdha1),ENSMUSG00000047674(Pdha2)" "ENSG00000131828(PDHA1),ENSG00000163114(PDHA2)" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" FBgn0283451 br broad http://flybase.net/reports/FBgn0283451.html "FBgn0000210, FBgn0000801, FBgn0001373, FBgn0001374, FBgn0001375, FBgn0001644, FBgn0001684, FBgn0002964, FBgn0003222, FBgn0005389, FBgn0005581, FBgn0010011, FBgn0026711, FBgn0027219, FBgn0027234, FBgn0028290, FBgn0028364, FBgn0029583, FBgn0029585, FBgn0029586, FBgn0029584" protein_coding_gene "0046872=metal ion binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0010629=negative regulation of gene expression, 0006914=autophagy, 0048813=dendrite morphogenesis, 0035070=salivary gland histolysis, 0008219=cell death, 0048747=muscle fiber development, 0042332=gravitaxis, 0035075=response to ecdysone, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0071390=cellular response to ecdysone, 0035193=larval central nervous system remodeling, 0009608=response to symbiont, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0007552=metamorphosis, 0007562=eclosion, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048808=male genitalia morphogenesis, 0040034=regulation of development, heterochronic, 0048477=oogenesis, 0035071=salivary gland cell autophagic cell death, 0001752=compound eye photoreceptor fate commitment" 0005634=nucleus "l(1)G0284a, Broad-Complex, BR_C, nprl, Broad complex, BR-C Z1, l(1)pp-1, Z3, non-pupariating, l(1)G0401, l(1)2Bb, lethal(1)non-pupariating-1, Z4, Broad Complex, npr1, l(1)npr-1, Br-C Z2, l(1)G0042, Br-C-Z3, BR-c, lethal(1)discs normal, PP2, broad complex, br-C, BRC-Z3, CG11491, uq, BRC-Z1, l(1)pp2, ecdysone-sensitivity, rds, br-Z1, l(1)2Bab, BR, lethal(1)2Bc, l(1)d.norm.1, BRC, l(1)d norm-12, l(1)G0318, Broad-complex, nrp1, l(1)ts132, broad-complex, Broad, lethal(1)2Bab, Br-Z4, EG:123F11.1, rdp, BRC-Z4, l(1)pp1, rbp, l(1)ts376, l(1)G0018, npr, BrZ3, unequal wings, overlapping-complementation-complex, nrp, l(1)2Bad, de12, BrC-Z1, CG11514, l(1)2Bd, l(1)ESHS5, BRC-Z2, ecs, l(1)ts144, BR-C, CG11509, 2Bc, l(1)npr1, br-Z3, l(1)dn1, CG11511, reduced bristles on palps, Br, br-Z4, l(1)ts358, l(1)G0284, l(1)2Ba, unnamed, EG:25D2.1, Z1, l(1)pp-2, l(1)2Bc, o.c.c., A18, br-Z2, PP1, Br-C, l(1)PP1, l(1)n34, BrC, 2B5, non-pupariating-1, Z2, lethal(1)2Bd, npr-1, EG:17A9.1, reduced palps" "IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like, IPR011333=POZ domain, IPR007087=Zinc finger, C2H2" CG11491 16-Dec-15 2015_12 "ENSDARG00000061110(zbtb44),ENSDARG00000070864(bcl6a)" ENSXETG00000021232() "viable,lethal,some die during pupal stage,neuroanatomy defective,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage,gravitaxis defective,lethal - all die before end of pupal stage,female fertile,male fertile,visible,heat sensitive,developmental rate defective,female sterile,chemical resistant,long lived,male,Minute,immune response defective,somatic clone,partially,body color defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,eye color defective,fertile,flightless,decreased cell death,reduced,female,cold sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,maternal effect,partially lethal - majority die,good,locomotor behavior defective,some die during third instar larval stage" "dorsal multidendritic neuron ddaC,polytene chromosome puff,dorsal appendage,embryonic/larval hemocyte | third instar larval stage,pupa,leg,optic lobe,adult brain,wing,maxillary palpus,maxillary palpus & macrochaeta,rostral membrane,ovary,embryonic/larval salivary gland,embryonic/larval proventriculus,indirect flight muscle,endochorion,chorion,egg operculum,somatic clone,wing margin & sensory neuron | somatic clone,chemosensory ventral triple row bristle,imaginal disc,ommatidium,morphogenetic furrow,photoreceptor cell,supernumerary,photoreceptor cell R8,eye,embryonic/larval central nervous system,maxillary palp bristle,ectopic,cold sensitive,male genitalia,chaeta,heat sensitive,socket,adult cuticle,microchaeta,macrochaeta,head bristle,mesothoracic bristle,metathoracic bristle,adult abdominal sensillum,abdominal dorsal trichome,tergite,follicle cell,ovary & nucleus | conditional cs,micropyle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,dorsal medial muscle,mesothoracic extracoxal depressor muscle 66,pigment cell,abdomen,scutellar bristle,medulla,lobula plate,Malpighian tubule,yellow body,metathoracic tarsal segment,metathoracic leg,adult head,egg,germline clone,muscle tendon junction & coxal tergal remotor muscle,muscle tendon junction & tergosternal muscle,muscle tendon junction & lateral oblique dorsal muscle,tendon cell,thorax,adult epidermis,salivary gland,abdominal sternite bristle,embryonic/larval somatic muscle,ring gland,microchaeta & thorax,microchaeta & adult thorax,embryonic/larval esophagus,lobula,embryonic/larval midgut,ventral thoracic disc,puparium,sensory neuron & dorsal mesothoracic discbbg-C96,wing margin & sensory neuronbbg-C96,prothoracic gland,LNv neuron,trichogen cell,mesothoracic tergum" DRSC17788 IE 1.510314494 0.858648982 2.957708144 -0.579072964 -0.053337797 -1.485471636 FBgn0051481 pb proboscipedia http://flybase.net/reports/FBgn0051481.html "FBgn0003040, FBgn0010841, FBgn0063631" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0007382=specification of segmental identity, maxillary segment, 0007381=specification of segmental identity, labial segment, 0048728=proboscis development" 0005634=nucleus "proboscopedia, Dmpb, Pb, proposcipedia, CG17880, pd, PB, CG31481, BG:DS01719.1, l(3)04498, Proboscipedia, pr" "IPR020479=Homeodomain, metazoa, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001827=Homeobox protein, antennapedia type, conserved site, IPR001356=Homeobox domain" CG31481 16-Dec-15 2015_12 ENSMUSG00000048763(Hoxb3) "ENSG00000120093(HOXB3),ENSG00000105997(HOXA3),ENSG00000128652(HOXD3)" embryonic stage&&larval stage&&pupal stage " embryonic stage | 6hr , embryonic stage " " stomodeum | posterior to

, embryonic/larval foregut

, embryonic central nervous system | restricted

, embryonic mandibular segment

, subesophageal ganglion

, mesoderm | presumptive

, mesothoracic segment &&of ventral nerve cord

, prothoracic segment | posterior ventral nerve cord

, metathoracic segment &&of ventral nerve cord

, embryonic labial segment

, supraesophageal ganglion

, embryonic maxillary segment

" "visible,recessive,lethal,heat sensitive,dominant,wild-type,male,female,homeotic,somatic clone,temperature conditional,lethal - all die before end of pupal stage,some die during pupal stage" "labellum,distal,maxillary palpus,labellar cap,pseudotrachea,arista,ectopic,heat sensitive,tarsal segment & mouthpart | conditional ts, with pb27/pb20,sex comb,sex comb & prothoracic leg | conditional ts,prothoracic leg,prothoracic tarsal segment,leg,tarsal segment,embryonic head,tarsal segment & mouthpart | conditional ts, with pb20, pb27,T1 beard,extended germ band embryo,larval head,mesothoracic tarsal segment,metathoracic tarsal segment,antenna,prothoracic leg & sex comb,third segment of antenna,second segment of antenna,head,posterior vertical bristle,eye,anterior,dorsal row,ventral row,microchaeta & wing,wing sensillum,wing vein L3 & macrochaeta,macrochaeta,fourth segment of antenna,wing vein L3,ventral,ommatidium,interommatidial bristle,posterior,wing,labial disc,antennal sense organ,tarsal segment & mouthpart,proboscis,macrochaeta & prementum,labial segment,somatic clone,unguis,pulvillus,tarsal segment & mouthpart | conditional ts, with pbQ50K.hs,tarsal segment & mouthpart | conditional ts, with pb27, pbQ50K.hs,temperature conditional,proboscis & sex comb | ectopic,tarsal segment & mouthpart | conditional ts, with pb20, pbQ50K.hs,wing & macrochaetadpp.blk1,wing vein,crossvein,imaginal disc,wing margin,embryonic tritocerebrum,prothoracic ventral intersegmental muscle,mesothoracic ventral oblique muscle 2,metathoracic ventral acute muscle,visceral mesoderm,midgut chamber 1,gastric caecum primordium" FBgn0003015 osk oskar http://flybase.net/reports/FBgn0003015.html protein_coding_gene "0008103=oocyte microtubule cytoskeleton polarization, 0040040=thermosensory behavior, 0035282=segmentation, 0048477=oogenesis, 0008542=visual learning, 0007281=germ cell development, 0007315=pole plasm assembly, 0007279=pole cell formation, 0007314=oocyte anterior/posterior axis specification, 0007632=visual behavior, 0007277=pole cell development, 0046594=maintenance of pole plasm mRNA location, 0019094=pole plasm mRNA localization, 0007616=long-term memory, 0007278=pole cell fate determination, 0045727=positive regulation of translation, 0046011=regulation of oskar mRNA translation, 0030719=P granule organization, 0007359=posterior abdomen determination, 0043488=regulation of mRNA stability, 0008595=anterior/posterior axis specification, embryo, 0007318=pole plasm protein localization" "0005938=cell cortex, 0043186=P granule, 0045495=pole plasm" "norka, OSK, Dmoskar, CG10901, Oskar, Osk, Dm-osk" "IPR025605=OST-HTH/LOTUS domain, IPR013830=SGNH hydrolase-type esterase domain" CG10901 16-Dec-15 2015_12 " oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >S8 , embryonic stage | early , adult stage && oogenesis stage | stage >S10 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-7 , oogenesis stage " " germarium region 2b

, oocyte | dorsal <&> anterior

,

posterior , oocyte

, oocyte | posterior

, nurse cell

" " embryonic stage | early , adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S9 " " pole granule

, oocyte | posterior

, egg chamber | posterior

" "lethal,maternal effect,recessive,visible,memory defective,learning defective,visual behavior defective,neurophysiology defective,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,wild-type,female sterile,dominant,decreased cell number,grandchildless,sterile,viable,increased cell death,male sterile,meiotic cell cycle defective,heat sensitive" "germline cell,embryonic head,pole cell,pole plasm,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,germinal proliferation center hub,embryo,germline clone,maternal effect,posterior,embryonic thorax,embryonic abdomen,embryonic epidermis,abdomen,ectopic,supernumerary,anterior,prothoracic ventral denticle belt,presumptive embryonic/larval muscle system,embryonic myoblast,cephalopharyngeal skeleton,microtubule & oocyte | oogenesis stage S9p-XT103),embryonic/first instar larval cuticle,denticle belt,pole granule,egg chamber,karyosome,oocyte,mouth hooks,prothoracic segment,gonad,germline stem cell,heat sensitive,embryonic/first instar larval cuticle & embryonic headnos.UTR.THsimVP16,extended germ band embryo,embryonic telson,embryonic/larval foregut,embryonic/larval hindgut,microtubule & oocyte | oogenesis stage S9mat.ë±Tub67C.THsimVP16,trichogen cell,filamentous actin & oocytemat.ë±Tub67C.THsimVP16" FBgn0051103 CG31103 http://flybase.net/reports/FBgn0051103.html FBgn0039292 protein_coding_gene 0005215=transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CG13655 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site" CG31103 16-Dec-15 2015_12 viable FBgn0027217 l(1)G0324 lethal (1) G0324 http://flybase.net/reports/FBgn0027217.html gene 16-Dec-15 2015_12 "lethal,partially lethal - majority die,recessive" FBgn0000183 BicD Bicaudal D http://flybase.net/reports/FBgn0000183.html FBgn0025237 protein_coding_gene "0017137=Rab GTPase binding, 0032050=clathrin heavy chain binding, 0045502=dynein binding, 0003729=mRNA binding, 0005515=protein binding" "0007314=oocyte anterior/posterior axis specification, 0007309=oocyte axis specification, 0007310=oocyte dorsal/ventral axis specification, 2000302=positive regulation of synaptic vesicle exocytosis, 0050658=RNA transport, 0008103=oocyte microtubule cytoskeleton polarization, 0007294=germarium-derived oocyte fate determination, 0051028=mRNA transport, 0048477=oogenesis, 0016325=oocyte microtubule cytoskeleton organization, 2000370=positive regulation of clathrin-mediated endocytosis, 0008298=intracellular mRNA localization, 0048488=synaptic vesicle endocytosis, 0030727=germarium-derived female germ-line cyst formation, 0007293=germarium-derived egg chamber formation, 0030100=regulation of endocytosis, 0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 0070727=cellular macromolecule localization, 0030154=cell differentiation" "0005829=cytosol, 0005737=cytoplasm, 0005794=Golgi apparatus, 0030669=clathrin-coated endocytic vesicle membrane" "Bic[D], bicaudal D, Bicuadal-D, unnamed, anon-EST:fe2A11, Bic-D, BicaudalD, BIC-D, CG6605, anon-fast-evolving-2A11, almond, BICD, Bicaudal-D" "IPR018477=Bicaudal-D protein, microtubule-associated" CG6605 16-Dec-15 2015_12 WBGene00016611(bicd-1) ENSXETG00000023941() "ENSMUSG00000003452(Bicd1),ENSMUSG00000037933(Bicd2)" "ENSG00000151746(BICD1),ENSG00000185963(BICD2)" " adult stage && oogenesis stage , embryonic stage | early , adult stage | female , embryonic stage | late , larval stage && pupal stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage S8-10B , adult stage && oogenesis stage | stage S1-7 , pupal stage , adult stage | male , adult stage && oogenesis stage | stage >S11 , adult stage && oogenesis stage | stage >=S8 " " germarium region 1--3

, ovary

, oocyte

, cystocyte

{ v egl- } , oocyte | anterior

,

ubiquitous , nurse cell

" ", adult stage && oogenesis stage , oogenesis stage && adult stage | female , embryonic stage | early " " germarium region 2b && presumptive oocyte | anterior

, nurse cell

, cystocyte

, oocyte

, germarium region 1 && germline cyst

, ovary

,

ubiquitous , germarium region 2a && presumptive oocyte | anterior

, germarium region 1--3

, germarium region 3 && stage S1 oocyte | posterior

" "lethal,dominant,maternal effect,recessive,uncoordinated,female fertile,female sterile,male fertile,female semi-sterile,partially lethal - majority die,some die during embryonic stage,locomotor behavior defective,neurophysiology defective,lethal - all die before end of P-stage,some die during P-stage,wild-type,viable" "hemocyte,embryonic head,embryonic thorax,embryo,macrophage,anterior,egg chamber,nurse cell ring canal,oocyte,germline cyst,ovary,synaptonemal complex,synaptonemal complex | ectopic,dorsal appendage,egg,chorion,embryonic neuroblast,embryonic neuroblast & spindleTW119), with BicDHA40.TIvirHA1,embryonic neuroblast & spindle, with BicDHA40.TIvirHA1, Df(2L)TW119,photoreceptor cell | precursor & nucleus,germline clone,pole granule,pole cell,presumptive embryonic/larval central nervous system,egg operculum,ovariole,oocyte nucleus,microtubule organizing center & oocyte,follicle cell,yolk granule,embryonic abdomen,ectopic,posterior,embryonic/first instar larval cuticle,photoreceptor cell & nucleusTW119),NMJ bouton,embryonic/larval somatic muscle,embryonic/larval neuromuscular junction,synaptic vesicleTW119),synaptonemal complex | germline clone,cystocyte,cell non-autonomous,centrosome,germarium region 2a,retina,embryonic/larval optic stalk,yolk granuleTW119),embryonic neuroblast & spindle, with Df(2L)TW119/BicDR26,embryonic neuroblast & spindle, with BicDR26, Df(2L)TW119,lipid particlenos.UTR.THsimVP16,border follicle cell" FBgn0004878 cas castor http://flybase.net/reports/FBgn0004878.html "FBgn0005769, FBgn0011311, FBgn0011466, FBgn0014137, FBgn0037367" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0046872=metal ion binding" "0007419=ventral cord development, 0006357=regulation of transcription from RNA polymerase II promoter, 0014019=neuroblast development, 0040034=regulation of development, heterochronic, 0016319=mushroom body development, 0009791=post-embryonic development, 0006355=regulation of transcription, DNA-templated, 0007402=ganglion mother cell fate determination, 0045892=negative regulation of transcription, DNA-templated, 0048699=generation of neurons, 0021782=glial cell development, 0007417=central nervous system development" 0005634=nucleus "CG2102, Castor, ming, Cas, l(3)j1C2, l(3)neo33" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR017956=AT hook, DNA-binding motif" CG2102 16-Dec-15 2015_12 ENSXETG00000006312(CASZ1) " embryonic stage , embryonic stage | stage 5 " " neuroblast NB2-3

, neuroblast NB7-2

, neuroblast NB7-4

, neuroblast NB7-1

, midline glial cell

, neuroblast NB6-1

, neuroblast NB3-3

, neuroblast NB3-2

, neuroblast

, procephalic neurogenic region

, ventral midline

, ganglion mother cell

, neuroblast NB2-4

, central nervous system | restricted

, neuroblast NB3-1

, supraesophageal ganglion

, organism | 10-40% egg length

, embryonic central nervous system

, neuroblast NB5-3

, neuroblast NB4-1

, neuroblast NB5-6

, neuroblast NB5-2

, neuroblast MNB

, neuroblast NB3-4

, neuroblast NB1-1

, neuroblast NB5-1

, neuroblast NB2-1

" embryonic stage | stage 9-11 " tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

, deuterocerebral neuroblast | subset

, procephalic neurogenic region | restricted

" "lethal - all die during larval stage,some die during first instar larval stage,some die during second instar larval stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,male,visible,partially lethal - majority die,some die during pupal stage" "mushroom body beta-lobe,adult mushroom body,adult mushroom body beta'-lobe,posterior commissure,U4 neuron,supernumerary,neuroblast,presumptive embryonic/larval central nervous system,neuroblast NB5-6 of thorax,subesophageal ganglion neuron,ellipsoid body,cell non-autonomous,somatic clone,U5 neuron,eye,macrochaeta,trichogen cell,mesothoracic tergum,thoracic neuroblast,neuroblast NB3-3,EL neuron" FBgn0001078 ftz-f1 ftz transcription factor 1 http://flybase.net/reports/FBgn0001078.html "FBgn0010807, FBgn0040788" protein_coding_gene "0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0000976=transcription regulatory region sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0008270=zinc ion binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003712=transcription cofactor activity" "0016322=neuron remodeling, 0002165=instar larval or pupal development, 0006357=regulation of transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035626=juvenile hormone mediated signaling pathway, 0007552=metamorphosis, 0035071=salivary gland cell autophagic cell death, 0040034=regulation of development, heterochronic, 0016319=mushroom body development, 0042048=olfactory behavior, 0008219=cell death, 0007365=periodic partitioning, 0055088=lipid homeostasis, 0043401=steroid hormone mediated signaling pathway, 0006355=regulation of transcription, DNA-templated, 0007480=imaginal disc-derived leg morphogenesis, 0048813=dendrite morphogenesis, 0035074=pupation, 0009725=response to hormone, 0035073=pupariation, 0035075=response to ecdysone" "0005634=nucleus, 0005737=cytoplasm" "betaFTZ-F1, FTZ-F1A, FTZ-F1, beta-Ftz transcription factor 1, ftz-F1, DEP1, ftz-transcription factor 1, fushi tarazu transcription factor 1, bFTZ-F1, beta-FTZ-F1, beta Ftz-f1, ftzf1, beta-Ftz-F1, FTZ-F1alpha, BFTZ-F1, betaFtz-F1, ftz factor 1, betaftz-F1, DmFTZ-F1, alphaftz-f1, Ftz interacting protein 1, betaFtz-f1, dmFTZ-f1, FIP1, betaftz-f1, l(3)03649, CG4059, FTZf1alpha, FTZ-Fl, alphaFTZF1, ftz-f1alpha, beta FTZ-F1, Ftz-F1, NR5A3, alphaFTZ-F1, dFTZ-F1alpha, Ftz-f1, betaftzf1, CG13378, dFtz-F1alpha, betaFTZF1, FTZF1" "IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001723=Nuclear hormone receptor, IPR016355=Nuclear hormone receptor family 5, IPR013088=Zinc finger, NHR/GATA-type, IPR001628=Zinc finger, nuclear hormone receptor-type" CG4059 16-Dec-15 2015_12 "ENSDARG00000042556(nr5a2),ENSDARG00000023362(nr5a1b),ENSDARG00000017704(nr5a1a),ENSDARG00000039116(nr5a5)" WBGene00006790(unc-55) "ENSXETG00000000314(nr5a2),ENSXETG00000011456(NR5A1)" "ENSMUSG00000026398(Nr5a2),ENSMUSG00000026751(Nr5a1)" "ENSG00000116833(NR5A2),ENSG00000136931(NR5A1)" " embryonic stage , embryonic stage | late , prepupal stage | 6-8 hr , adult stage , embryonic stage | early , embryonic stage | 14-22 hr " " embryonic stage | 16-19 hr , larval stage && adult stage , embryonic stage | late , prepupal stage , embryonic stage | early " "lethal,recessive,neuroanatomy defective,viable,fertile,maternal effect,pair rule phenotype,non-rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,germline clone,partially,lethal - all die before end of pupal stage,some die during pupal stage,visible,increased cell death,heat sensitive,developmental rate defective,wild-type,lethal - all die before end of prepupal stage,some die during prepupal stage,decreased cell death,lethal - all die before end of larval stage,majority die during third instar larval stage,some die during second instar larval stage" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,embryonic/larval cuticle,mushroom body | adult stage,adult mushroom body,abdominal 9 ventral denticle belt,denticle belt,parasegment,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,mesothoracic ventral denticle belt,parasegment 2,parasegment 4,parasegment 6,parasegment 8,parasegment 10,parasegment 12,parasegment 14,embryo,macrochaeta,embryonic/larval salivary gland,Malpighian tubule,optic lobe,larval neuromere,leg,wing disc,midgut,cuticle,maternal effect,segment,head,pupal cuticle,adult head,salivary gland,heat sensitive,cephalopharyngeal skeleton,embryonic/larval anterior spiracle,embryonic/larval posterior spiracle,embryonic/larval tracheal system,mouth hooks,epicuticle,endocuticle,embryonic/larval spiracle,pupa,femur & macrochaeta,tibia & macrochaeta,ventral thoracic disc,metathoracic leg,embryonic/first instar larval cuticle,embryonic epidermis,embryonic segment,germline clone,embryonic head,dorsal,embryonic thorax,heart primordium,embryonic abdominal segment 1 & muscle founder cell,embryonic abdominal segment 3 & muscle founder cell,embryonic abdominal segment 1 & cardioblast,embryonic abdominal segment 3 & cardioblast,embryonic/larval salivary gland | embryonic stage,prothoracic gland,lipid particlephm.PO,ovariole" FBgn0003870 ttk tramtrack http://flybase.net/reports/FBgn0003870.html "FBgn0011319, FBgn0011402, FBgn0011681, FBgn0039865, FBgn0039866" protein_coding_gene "0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003682=chromatin binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0003677=DNA binding, 0031208=POZ domain binding, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0042803=protein homodimerization activity, 0046872=metal ion binding" "0040003=chitin-based cuticle development, 0016476=regulation of embryonic cell shape, 0043388=positive regulation of DNA binding, 0035001=dorsal trunk growth, open tracheal system, 0048053=R1/R6 development, 0060446=branching involved in open tracheal system development, 0048750=compound eye corneal lens morphogenesis, 0045467=R7 cell development, 0001709=cell fate determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048854=brain morphogenesis, 0008360=regulation of cell shape, 0048813=dendrite morphogenesis, 0045892=negative regulation of transcription, DNA-templated, 0035151=regulation of tube size, open tracheal system, 0006357=regulation of transcription from RNA polymerase II promoter, 0030707=ovarian follicle cell development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0042675=compound eye cone cell differentiation, 0002121=inter-male aggressive behavior, 0007476=imaginal disc-derived wing morphogenesis, 0007298=border follicle cell migration, 0031987=locomotion involved in locomotory behavior, 0001964=startle response, 0007426=tracheal outgrowth, open tracheal system, 0007422=peripheral nervous system development, 0035147=branch fusion, open tracheal system, 0042682=regulation of compound eye cone cell fate specification, 0048666=neuron development, 0046843=dorsal appendage formation" "0005700=polytene chromosome, 0005634=nucleus, 0017053=transcriptional repressor complex" "1260/10, ttk/FTZ-F2, Ttk, l(3)j7B8, tramtrack69, Tramtrack, ftz-f2, Ttk88, Ttk88 repressor, oversensitive, Ttk69, Tramtrack69, Enhancer of yan at 100D, ttkp69, 1396/14, 1209/10, 0250/25, schmal, 1049/07, TTK, l(3)02667, oss, 3540, l(3)j2A1, CG11558, 0037/17, tramtrack-69, 1281/04, Tramtrak, ttk69, twk, anon-EST:Liang-2.9, tramtrak, 1119/04, 5311, clone 2.9, 1418/06, 0438/31, TTK69, 1209/05, ovs, 5125, CG1856, TTK88, Tramtrack88, E(yan)100D, ftzf2/ttk, 1184/16, FTZ-F2, osn, TTKA, 1372/08, 0702/07, 1325/15" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR017956=AT hook, DNA-binding motif, IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR007087=Zinc finger, C2H2" CG1856 16-Dec-15 2015_12 ENSG00000160877(NACC1) " embryonic stage | stage >=7 , embryonic stage | syncytial blastoderm , embryonic stage | gastrula , embryonic stage | early , embryonic stage | stage 9-11 , adult stage , embryonic stage | extended germ band , embryonic stage | stage >=8 , embryonic stage | stage 9 " " pole cell

,

ubiquitous , yolk nucleus | restricted

, mesoderm | restricted

, stomodeum

, posterior midgut proper primordium

, anterior midgut proper primordium

,

segment polarity , tracheal pit

, ectoderm | restricted

" " pupal stage , pupal stage | >=36 hr " " secondary pigment cell

, photoreceptor cell

, primary pigment cell

, vibrissae | subset

, tertiary pigment cell

, cone cell

" "lethal,viable,neuroanatomy defective,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,stress response defective,behavior defective,sleep defective,male limited,partially lethal - majority die,visual behavior defective,semidominant,cell lethalcell lethal,female sterile,cell shape defective,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,mitotic cell cycle defective,dominant,increased cell death,decreased cell size" "border follicle cell,somatic clone,embryonic/larval dorsal trunk,eye,lens,eye photoreceptor cell,rhabdomere,ommatidial precursor cluster,abdominal lateral pentascolopidial chordotonal organ lch5,lch5 neuron,supernumerary,ommatidium,interommatidial bristle,photoreceptor cell R7,cone cell,Kenyon cell,adult mushroom body,sensory neuron,presumptive embryonic/larval peripheral nervous system,thecogen cell,scolopidial dendritic cap cell,external sensory organ,socket,trichogen cell,tormogen cell,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,neuron,macrochaeta,scolopale,microchaeta,dorsal appendage,maternal effect,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere R7,rhabdomere R8,egg chamber,egg,follicle cell,oocyte,germline clone,extended germ band embryo,heat sensitive,multidendritic neuron,chordotonal organ,scolopidial neuron,macrochaeta & leg,commissure,longitudinal connective,exit glial cell,presumptive embryonic/larval tracheal system,embryonic/larval visceral branch,embryonic/larval dorsal branch,embryonic/larval lateral trunk,embryonic/larval cuticle,procuticle,taenidium,taenidial fold,thecogen cell & peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic epidermis,filzkorper,mouth hooks,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,embryonic/larval glial cell,cell autonomous,midline glial cell,embryonic head,embryonic/first instar larval cuticle,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,dorsal triple row,mechanosensory ventral triple row bristle,eye disc,photoreceptor cell R4,photoreceptor cell R3,wing,dorsal mesothoracic disc & sensory mother cellBx-MS1096,intersegmental nerve,interface glial cell,ventral nerve cord primordium,mitotic cell cycleGMR.PF,ommatidium | adult stage,eye disc | pupal stage,ommatidium | pupal stage,cone cell | pupal stage,photoreceptor cell | pupal stage,medial triple row,chemosensory ventral triple row bristle,sensory mother cell & dorsal mesothoracic discBx-MS1096,ventral triple row,photoreceptor cell,eye-antennal disc,morphogenetic furrow,lamina anlage glial cell,subretinal glial cell,lamina neuropil,peripheral nervous system,ommatidium | third instar larval stage,photoreceptor cell R1 | third instar larval stage,photoreceptor cell R6 | third instar larval stage,photoreceptor cell R7 | third instar larval stage,cone cell | third instar larval stage,equatorial cone cell,polar cone cell,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite" DRSC17091 IE -1.233048772 -2.693205836 -1.676500078 2.398660052 0.212095878 0.200082962 FBgn0014388 sty sprouty http://flybase.net/reports/FBgn0014388.html protein_coding_gene "0007430=terminal branching, open tracheal system, 0007424=open tracheal system development, 0035155=negative regulation of terminal cell fate specification, open tracheal system, 0008293=torso signaling pathway, 0046580=negative regulation of Ras protein signal transduction, 0060446=branching involved in open tracheal system development, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0030707=ovarian follicle cell development, 0007429=secondary branching, open tracheal system, 0001745=compound eye morphogenesis, 0040037=negative regulation of fibroblast growth factor receptor signaling pathway, 0045314=regulation of compound eye photoreceptor development, 0001763=morphogenesis of a branching structure, 0016318=ommatidial rotation, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0007173=epidermal growth factor receptor signaling pathway, 0008595=anterior/posterior axis specification, embryo, 0007426=tracheal outgrowth, open tracheal system, 0009968=negative regulation of signal transduction, 0048747=muscle fiber development, 0021782=glial cell development" "0005886=plasma membrane, 0005622=intracellular" "sprouty, STY, spry, dSPRY, dSprouty, Spry, Calcineurin suppressor, chromosome 3, group 3, Sty, CG1921, CS3-3, Sry, Sprouty" IPR007875=Sprouty CG1921 16-Dec-15 2015_12 "ENSDARG00000024286,ENSDARG00000036108(LOC100330834),ENSDARG00000033089(LOC100003704),ENSDARG00000068732(spry4)" "ENSXETG00000019568(SPRY4),ENSXETG00000001573(spry1),ENSXETG00000017807(spry2)" "ENSMUSG00000061654,ENSMUSG00000022114(Spry2),ENSMUSG00000024427(Spry4)" "ENSG00000168939(SPRY3),ENSG00000136158(SPRY2),ENSG00000187678(SPRY4),ENSG00000164056(SPRY1)" " embryonic stage | late , embryonic stage | stage >=12 , embryonic stage | 5-22 hr " " neuron &&of ventral nerve cord

, embryonic/larval tracheal system

, oenocyte

, midline glial cell

, embryonic/larval dorsal vessel

" "visible,viable,fertile,neuroanatomy defective,lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,dominant" "wing vein,synapse,eye,fascicle | third instar larval stage,embryonic/larval dorsal branch,embryonic/larval ganglionic branch,ommatidium,cone cell,mystery cell,chordotonal organ,midline glial cell,egg,dorsal appendage,ganglionic branch 2,cell non-autonomous,somatic clone,embryonic/larval dorsal branch 1,lateral trunk anterior branch,lateral trunk posterior branch,embryonic/larval visceral branch,ovary,germline clone,terminal tracheal cell,supernumerary,outer photoreceptor cell,dorsal air sac primordium,maternal effect,embryonic/larval tracheal system,eye photoreceptor cell,primary pigment cell,pigment cell,five-cell ommatidial precursor cluster,ommatidial precursor cluster,wing,hemocyte | late embryonic stage,wing vein L3,wing vein L2,wing vein L4,photoreceptor cell R1,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R6,photoreceptor cell R7,interommatidial bristle,embryo,muscle founder cell,embryonic/larval optic stalk surface glial cell | third instar larval stage" FBgn0004635 rho rhomboid http://flybase.net/reports/FBgn0004635.html "FBgn0003251, FBgn0003972, FBgn0026834" protein_coding_gene 0004252=serine-type endopeptidase activity "0007436=larval salivary gland morphogenesis, 0016337=single organismal cell-cell adhesion, 0048149=behavioral response to ethanol, 0007424=open tracheal system development, 0007438=oenocyte development, 0007173=epidermal growth factor receptor signaling pathway, 0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0048865=stem cell fate commitment, 0000281=mitotic cytokinesis, 0008586=imaginal disc-derived wing vein morphogenesis, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0007474=imaginal disc-derived wing vein specification, 0035225=determination of genital disc primordium, 0035160=maintenance of epithelial integrity, open tracheal system, 0007611=learning or memory, 0007422=peripheral nervous system development, 0007432=salivary gland boundary specification, 0010629=negative regulation of gene expression, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0008355=olfactory learning, 0035311=wing cell fate specification, 0007409=axonogenesis, 0001763=morphogenesis of a branching structure, 0030707=ovarian follicle cell development, 0035202=tracheal pit formation in open tracheal system, 0007431=salivary gland development, 0007479=leg disc proximal/distal pattern formation, 0038005=peptide bond cleavage involved in epidermal growth factor receptor ligand maturation, 0007476=imaginal disc-derived wing morphogenesis, 0007420=brain development" "0005887=integral component of plasma membrane, 0005783=endoplasmic reticulum, 0005794=Golgi apparatus, 0005886=plasma membrane, 0045177=apical part of cell, 0016021=integral component of membrane" "DRORHO, DMRHO, iks, Rhomboid 1, DMRHOa, ve, Rho-1, Ve, rhomboid-1, Veinlet, rhomboid1, RHO, rhom, RHOb, CG1004, rho1, DMRHOb, rhomboid/veinlet, Dmel\rho, Rho1, Rho, Dmrho, rho-1, Rhomboid, Rhomboid-1, veinlet" "IPR022764=Peptidase S54, rhomboid domain, IPR002610=Peptidase S54, rhomboid, IPR017213=Peptidase S54, rhomboid, metazoan" CG1004 16-Dec-15 2015_12 ENSDARG00000070311(rhbdl3) WBGene00004400(rom-1) ENSXETG00000005270(rhbdl2) " pupal stage , oogenesis stage | early , embryonic stage | stage 10-15 , embryonic stage , larval stage&&pupal stage , embryonic stage | stage >=12 , embryonic stage&&pupal stage&&adult stage , adult stage && oogenesis stage , embryonic stage | stage 6,7 , embryonic stage | stage 5 , oogenesis stage , oogenesis stage | late , embryonic stage | stage >=13 , embryonic stage | stage 7-12 " " crossvein

, follicle cell

{ 0 Egfr* } , wing vein L4

, embryonic central brain

subset , tracheal pit

, wing vein L3

, wing vein L2 | precursor

, central nervous system | segmentally repeated

, wing vein L1

, wing vein L5 | precursor

, wing vein L4 | precursor

, wing vein L5

, follicle cell

{ - grk* } , wing vein | precursor

, Malpighian tubule tip cell

, follicle cell

{ + fs(1)K10* } , wing vein L2

, mesectoderm

, wing vein L3 | precursor

, wing vein L1 | precursor

, organism | ventro-lateral & restricted

, wing vein

, follicle cell

{ 0 grk* } , follicle cell

, chordotonal organ | precursor

,

segment boundary , embryonic foregut

ventral & anterior , ventral midline

, follicle cell

{ - Egfr* } " " larval stage | third instar , adult stage && oogenesis stage " " photoreceptor cell R2 | presumptive

, ommatidium

, photoreceptor cell R5 | presumptive

, follicle cell

, photoreceptor cell R8 | presumptive

" "visible,recessive,viable,dominant,learning defective,memory defective,chemical sensitive,lethal - all die before end of embryonic stage,neuroanatomy defective,some die during embryonic stage,lethal,heat sensitive,flightless,increased cell number" ",tracheal system,wing,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,scolopidium,scolopidial dendritic cap cell,scolopidial neuron,Keilin's organ,antenno-maxillary complex,abdominal lateral longitudinal muscle,abdominal dorsal oblique muscle,abdominal dorsal acute muscle,abdominal ventral longitudinal muscle,somatic muscle,abdominal ventral oblique muscle,midline glial cell,RP3 motor neuron,wing vein,abdominal lateral pentascolopidial chordotonal organ,abdominal ventral monoscolopidial chordotonal organ,ventral thoracic disc primordium,dorsal mesothoracic disc primordium,RP2 motor neuron,dorsal neurohemal organ,bract,dorsal appendage,eye,segment border muscle,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,ventral nerve cord commissure,embryonic/larval salivary gland,wing margin,chordotonal organ,embryonic/larval optic lobe,adult eye primordium,optic lobe,Bolwig organ,egg,crossvein,interommatidial bristle,ommatidium,yellow ommatidium,embryonic/first instar larval cuticle,abdominal ventral denticle belt,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,sensory neuron,motor neuron,embryonic/larval dorsal trunk,dendritic arborizing neuron,axon,embryonic/larval tracheal system,embryonic/larval visceral branch,embryonic/larval oenocyte,pale ommatidium,tracheal branch primordium,cephalopharyngeal skeleton,anterior commissure,posterior commissure,genital disc primordium,embryonic ventral nervous system,anal pad,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,embryonic Malpighian tubule,embryonic central brain,circumesophageal tract,adult salivary gland primordium,embryonic ventral epidermis,photoreceptor cell,tracheal primordium,presumptive embryonic/larval tracheal system,mesoderm,lch5 cap attachment cell,lch5 ligament attachment cell,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,MP1 neuron,A1-7 ventral acute muscle 2,embryonic/larval trachea,VUM neuron,denticle,ganglionic branch 1 |,muscle founder cell |,chorion,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic prothoracic segment,oenocyte primordium,embryonic/larval oenocyte precursor,cone cell,pigment cell,dorsal hair,-109-68,wing disc,posterior crossvein,anterior crossvein" DRSC08734 I -0.746884187 2.111964777 0.278130487 0.250288545 -0.37531931 -0.070061948 FBgn0035656 CG10479 http://flybase.net/reports/FBgn0035656.html protein_coding_gene IPR000980=SH2 domain CG10479 16-Dec-15 2015_12 "ENSDARG00000054340(sla1),ENSDARG00000020788(sla2)" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0001085 fz frizzled http://flybase.net/reports/FBgn0001085.html "FBgn0036418, FBgn0036420" protein_coding_gene "0004888=transmembrane signaling receptor activity, 0042813=Wnt-activated receptor activity, 0017147=Wnt-protein binding" "0007165=signal transduction, 0001738=morphogenesis of a polarized epithelium, 0007476=imaginal disc-derived wing morphogenesis, 0035320=imaginal disc-derived wing hair site selection, 0007163=establishment or maintenance of cell polarity, 0007298=border follicle cell migration, 0016318=ommatidial rotation, 0030010=establishment of cell polarity, 0016055=Wnt signaling pathway, 0045198=establishment of epithelial cell apical/basal polarity, 0035159=regulation of tube length, open tracheal system, 0007507=heart development, 0007435=salivary gland morphogenesis, 0008105=asymmetric protein localization, 0032231=regulation of actin filament bundle assembly, 0060070=canonical Wnt signaling pathway, 0007464=R3/R4 cell fate commitment, 0045773=positive regulation of axon extension, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0008356=asymmetric cell division, 0001745=compound eye morphogenesis, 0008104=protein localization, 0045746=negative regulation of Notch signaling pathway, 0042067=establishment of ommatidial planar polarity, 0007186=G-protein coupled receptor signaling pathway, 0048675=axon extension, 0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity, 0035206=regulation of hemocyte proliferation, 0035317=imaginal disc-derived wing hair organization, 1902669=positive regulation of axon guidance, 0007164=establishment of tissue polarity, 0016360=sensory organ precursor cell fate determination" "0005886=plasma membrane, 0005938=cell cortex, 0016021=integral component of membrane, 0005887=integral component of plasma membrane, 0005768=endosome" "dFz, DFz1, CG3646, frizzled, fz1, CG17697, Frizzled 1, fz[[1]], DFZ1, Dm Fz1, Dfz, Frz, DFz, Dfz1, Fz, Fz1, Frizzled, frizzled 1, FZ, frz, frizzled[[1]], Frizzled1" "IPR026561=Frizzled, invertebrates, IPR015526=Frizzled/secreted frizzled-related protein, IPR000539=Frizzled protein, IPR017981=GPCR, family 2-like, IPR020067=Frizzled domain" CG17697 16-Dec-15 2015_12 "ENSDARG00000027589(fzd7b),ENSDARG00000054438(fzd2)" WBGene00003397(mom-5) "ENSXETG00000012404(fzd7),ENSXETG00000003463(FZD1),ENSXETG00000008840(fzd2)" "ENSMUSG00000041075(Fzd7),ENSMUSG00000050288(Fzd2),ENSMUSG00000044674(Fzd1)" "ENSG00000157240(FZD1),ENSG00000155760(FZD7),ENSG00000180340(FZD2)" " pupal stage , larval stage | third instar , embryonic stage , larval stage , adult stage | female , oogenesis stage && adult stage | female , embryonic stage | early , embryonic stage--pupal stage " " central nervous system

, larval brain

, eye-antennal disc

, ovary

, embryonic/larval proventriculus

,

ubiquitous , morphogenetic furrow

, wing

, epidermis

, imaginal disc

, ventral nerve cord

" " pupal stage , larval stage | third instar " " wing

, dorsal mesothoracic disc

, larval central nervous system

, imaginal disc

" "planar polarity defective,visible,viable,fertile,dominant,heat sensitive,wild-type,somatic clone,cell polarity defective,recessive,neuroanatomy defective,cell non-autonomous,cold sensitive,cell autonomous" "wing hair,wing,joint,ectopic,leg,macrochaeta,macrochaeta & adult thorax,ommatidium,heat sensitive,eye,wing & microchaeta | distal,supernumerary,embryonic epidermis,somatic clone,photoreceptor cell R4,photoreceptor cell R3,axon & dorsal cluster neuron,trichome & pleural membrane | somatic clone | cell non-autonomous,trichome & pleural membrane | somatic clone,trichome & adult abdomen | somatic clone | cell non-autonomous,trichome & adult abdomen | somatic clone,border follicle cell,polar follicle cell,cell non-autonomous,trichome & pleural membrane | somatic cloneUbx.PdC, fzUAS.cSa,trichome & pleural membrane | somatic clone | cell non-autonomousUbx.PdC, fzUAS.cSa,trichome & pleural membraneen-e16E, fzUAS.cSa,dorsal wing blade,lens,cold sensitive,wing & macrochaeta,RP2 motor neuron,macrochaeta & adult abdomen | somatic clone | cell non-autonomous,microchaeta & adult abdomen | somatic clone | cell non-autonomous,microchaeta & adult thorax | somatic clone | cell non-autonomous,bract,tarsal segment,wing disc,presumptive embryonic salivary gland,eye photoreceptor cell,wing cell,trichome & pleural membranehh-Gal4, fzUAS.cSa,embryonic/larval dorsal trunk,mesothoracic tergum & sensory mother cell & spindle,external sensory organ precursor cell I,external sensory organ precursor cell I & spindle,external sensory organ precursor cell I & centrosome,socket,spindle & external sensory organ precursor cell I,macrochaeta & eye,trichogen cell,embryonic neuroblast,wing & microchaeta,wing margin bristle,sensory mother cell,spindle,tarsal segment 1 & joint,tarsal segment 2,tarsal segment 3,tarsal segment 4,trichome & pleural membrane,trichome & abdominal tergite,wing margin,mesothoracic tergum,wing hair | P-stage,wing & microchaeta | distalDll-md23,microchaeta,sensory mother cell & spindleap-md52,denticle belt,embryonic/first instar larval cuticle,wing hair & 1st posterior cellptc-559.1,wing & microchaetaptc-559.1,anterior compartment,anterior/posterior compartment boundary,trichome & adult abdomenhh-Gal4,trichome & pleural membranehh-Gal4,trichome & pleural membraneë±Tub84B.PL,trichome & pleural membrane | somatic cloneUbx.PdC,trichome & pleural membrane | somatic clone | cell non-autonomousUbx.PdC,trichome & pleural membrane | somatic cloneUbx.PdC, fz15,trichome & pleural membrane | somatic clone | cell non-autonomousUbx.PdC, fz15,trichome & pleural membraneen-e16E, fz15,trichome & pleural membranehh-Gal4, fz21,trichome & pleural membraneen-e16E,denticle row 1,dorsal triple row,medial triple row,ventral triple row,lymph gland derived hemocyte | third instar larval stage,thorax" FBgn0023519 mRpL16 mitochondrial ribosomal protein L16 http://flybase.net/reports/FBgn0023519.html FBgn0019893 protein_coding_gene "0019843=rRNA binding, 0003735=structural constituent of ribosome" 0006412=translation 0005762=mitochondrial large ribosomal subunit "CG3109, L16, D15, EG:63B12.2, anon-2Bd, D-15" "IPR016180=Ribosomal protein L10e/L16, IPR000114=Ribosomal protein L16" CG3109 16-Dec-15 2015_12 ENSDARG00000005213(zgc:91951) WBGene00011412(T04A8.11) ENSXETG00000024210(MRPL16) ENSMUSG00000024683(Mrpl16) ENSG00000166902(MRPL16) "viable,visible" trichogen cell FBgn0035854 CG8005 http://flybase.net/reports/FBgn0035854.html protein_coding_gene "0008612=peptidyl-lysine modification to peptidyl-hypusine, 0050983=deoxyhypusine biosynthetic process from spermidine" "IPR029035=DHS-like NAD/FAD-binding domain, IPR002773=Deoxyhypusine synthase" CG8005 16-Dec-15 2015_12 ENSDARG00000003270(dhps) YHR068W(DYS1) WBGene00012460(Y17G7B.4) ENSXETG00000005599(dhps) ENSMUSG00000060038(Dhps) ENSG00000095059(DHPS) "viable,visible" trichogen cell FBgn0004198 ct cut http://flybase.net/reports/FBgn0004198.html "FBgn0000383, FBgn0001303, FBgn0029953, FBgn0062500" protein_coding_gene "0000976=transcription regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0048477=oogenesis, 0061332=Malpighian tubule bud morphogenesis, 0070983=dendrite guidance, 0008052=sensory organ boundary specification, 0045746=negative regulation of Notch signaling pathway, 0007424=open tracheal system development, 0048098=antennal joint development, 0008587=imaginal disc-derived wing margin morphogenesis, 0007605=sensory perception of sound, 0030713=ovarian follicle cell stalk formation, 0007469=antennal development, 0060288=formation of a compartment boundary, 0048813=dendrite morphogenesis, 0016360=sensory organ precursor cell fate determination, 0007417=central nervous system development, 0035277=spiracle morphogenesis, open tracheal system, 0007422=peripheral nervous system development, 0008585=female gonad development, 0007443=Malpighian tubule morphogenesis, 0000278=mitotic cell cycle, 0006355=regulation of transcription, DNA-templated, 0030707=ovarian follicle cell development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045165=cell fate commitment" 0005634=nucleus "CUT, l(1)7Bb, BcDNA:GH10590, kinked-femur, l(1)7Ba, Ct, kf, Cut, CG11387, cut, CT, l(1)VE614" "IPR010982=Lambda repressor-like, DNA-binding domain, IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR003350=CUT domain" CG11387 16-Dec-15 2015_12 ENSDARG00000058387(LOC565530) "ENSXETG00000005476(CUX1),ENSXETG00000011684(CUX2)" "ENSMUSG00000029705(Cux1),ENSMUSG00000042589" "ENSG00000160967(CUX1),ENSG00000111249(CUX2)" " embryonic stage | >5-6 hr , pupal stage , embryonic stage , adult stage , embryonic stage | >6-7 hr " " embryonic/larval posterior spiracle | surrounding

, embryonic/larval anterior spiracle | surrounding

, adult head

, external sensory organ

, embryonic central nervous system | presumptive | restricted

, Malpighian tubule

" " embryonic stage | 8 hr , prepupal stage | 0-2 hr , embryonic stage | >6-7 hr , adult stage , larval stage | third instar , embryonic stage | 10 hr , embryonic stage | 6-7 hr , embryonic stage | 5-6 hr , embryonic stage , embryonic stage | >5-6 hr , pupal stage | stage P6 , pupal stage | 24 hr , embryonic stage | stage > 9 , pupal stage | 6 hr , larval stage--adult stage , embryonic stage |>6 hr , prepupal stage | 3 hr , embryonic stage | stage 13 , adult stage && oogenesis stage | stage S2-14 " " desB neuron

, chemosensory sensory organ | precursor dorsal mesothoracic disc

, embryonic central nervous system | presumptive | restricted

, adult muscle system

, myoblast && mesothoracic tergum | distal

, v'esB neuron

, vesC neuron

, dorsal mesothoracic disc | restricted

, desD neuron

, des2 neuron

, lobula plate cortex

, chordotonal organ

, desC neuron

, lesA neuron

, lesB neuron

, embryonic/larval posterior spiracle | surrounding

, macrochaeta

, interommatidial bristle | precursor

, external sensory organ

, Malpighian tubule

, embryonic/larval anterior spiracle | surrounding

, pioneer neuron | precursor

, les3 neuron

, embryonic Malpighian tubule

, microchaeta

, chemosensory sensory organ &&of dorsal mesothoracic disc

, v'es3 neuron

, ventral thoracic disc | restricted

, cone cell

, v'es2 neuron

, tarsus | precursor

, vesB neuron

, imaginal tracheoblast

, v'esA neuron

, follicle cell

, adepithelial cell

, myoblast && mesothoracic tergum | proximal

, medulla cortex

, lesC neuron

" "lethal,recessive,visible,melanotic mass phenotype,homeotic,viable,neuroanatomy defective,wild-type,gravitaxis defective,fertile,male,reduced,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,male sterile,body color defective,female,partially lethal - majority die,poor,eye color defective,behavior defective,female sterile,cold sensitive,decreased cell number,somatic clone,mitotic cell cycle defective,cell lethal,germline clone,partially,increased cell size,neurophysiology defective,auditory perception defective,locomotor rhythm defective,planar polarity defective,hyperplasia" "femur,melanotic mass | third instar larval stage,melanotic mass | pupal stage,embryonic/larval hemocyte,supernumerary | third instar larval stage,leg,ectopic,antenna,wing,macrochaeta & wing,vibrissae,adult head,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,precursor,wing margin,wing blade,wing margin bristle,medial triple row,dorsal double row,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,wing & macrochaeta | posterior,dorsal-ventral compartment boundary of the wing,macrochaeta,scutum & macrochaeta,scutellum & macrochaeta,scutellar bristle,Malpighian tubule,adult spiracle,external sensory organ,central nervous system,triple row,ventral triple row,dorsal triple row,tergite,arista,eye,nurse cell,oocyte nucleus,egg chamber,chordotonal organ,scolopidium,thorax,wing vein,adult antennal lobe projection neuron DM5 lPN,antennal lobe glomerulus DM5,adult antennal lobe projection neuron VA5 lPN,antennal lobe glomerulus VA5,adult antennal lobe projection neuron DM2 lPN,antennal lobe glomerulus DM2,adult antennal lobe projection neuron DM1 lPN,antennal lobe glomerulus DM1,adult antennal lobe projection neuron DA1 vPN,antennal lobe projection neuron vPN,subesophageal ganglion,antennal lobe glomerulus VA1v,pigment cell,spiracular chamber,filzkorper,spiracular sense organ (obsolete FBbt00000431),multidendritic neuron,follicle cell,somatic clone,posterior spiracle primordium,nurse cell ring canal,dorsal multidendritic neuron ddaA,lateral multidendritic neuron ldaB,germarium,joint & antenna | somatic clone,epidermal cell,dendrite | somatic clone,indirect flight muscle,adepithelial cell of wing disc,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,mechanosensory chaeta,supernumerary,multidendritic dendrite,abdominal posterior ventral multidendritic neuron vdap,dendrite221,abdominal posterior ventral multidendritic neuron vdap | third instar larval stage,dorsal multidendritic neuron ddaB,dorsal multidendritic neuron ddaE,antennal lobe,antennal lobe projection neuron,class IV dendritic arborizing neuron,dendriteppk.PG,dorsal-ventral compartment boundary of the wing | third instar larval stage,actin cytoskeleton | ectopicsalm-459.2,trichogen cell,interommatidial bristle,embryonic/larval lymph gland" DRSC18757 EK -1.176195352 -0.123216743 0.186554477 -1.768505502 2.690592383 3.64887503 FBgn0038037 Cyp9f2 Cyp9f2 http://flybase.net/reports/FBgn0038037.html FBgn0027751 protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" "0055114=oxidation-reduction process, 0035220=wing disc development" "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "anon-EST:Posey150, cytochrome P450, CG11466, Cyp 9f2, 9f2, Cyp9F2" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG11466 16-Dec-15 2015_12 ENSDARG00000045627(cyp3a65) YHR007C(ERG11) "WBGene00008810(cyp-13A12),WBGene00008809(cyp-13A11),WBGene00014254(cyp-13A10),WBGene00011677(cyp-13A1),WBGene00011674(cyp-13A8),WBGene00010606(cyp-13B2),WBGene00008519(cyp-13B1)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "ENSMUSG00000056035(Cyp3a11),ENSMUSG00000075551(Cyp3a41a),ENSMUSG00000075552(Cyp3a41b),ENSMUSG00000054417(Cyp3a44),ENSMUSG00000038656(Cyp3a16),ENSMUSG00000029727(Cyp3a13),ENSMUSG00000029630(Cyp3a25),ENSMUSG00000070419(Cyp3a57),ENSMUSG00000061292(Cyp3a59)" "ENSG00000160868(CYP3A4),ENSG00000160870(CYP3A7),ENSG00000106258(CYP3A5),ENSG00000021461(CYP3A43),ENSG00000059377(TBXAS1)" "viable,fertile" wing margin FBgn0034800 CG3788 http://flybase.net/reports/FBgn0034800.html protein_coding_gene 0004850=uridine phosphorylase activity "0009166=nucleotide catabolic process, 0009116=nucleoside metabolic process" 0005737=cytoplasm "IPR018016=Nucleoside phosphorylase, conserved site, IPR018017=Nucleoside phosphorylase, IPR000845=Nucleoside phosphorylase domain, IPR010059=Uridine phosphorylase, eukaryotic" CG3788 16-Dec-15 2015_12 "ENSDARG00000036833(upp2),ENSDARG00000040869(LOC100330564)" WBGene00022817(upp-1) "ENSXETG00000010379(upp2),ENSXETG00000015681(upp1)" "ENSMUSG00000026839(Upp2),ENSMUSG00000020407(Upp1)" "ENSG00000007001(UPP2),ENSG00000183696(UPP1)" viable DRSC24502 K -0.448041247 0.7686463 -0.261816704 0.871332714 -0.812069781 2.056670242 FBgn0035995 CG3529 http://flybase.net/reports/FBgn0035995.html protein_coding_gene 0006886=intracellular protein transport 0005622=intracellular DmTOM1 "IPR004152=GAT domain, IPR014645=Target of Myb protein 1, IPR002014=VHS domain, IPR018205=VHS subgroup, IPR008942=ENTH/VHS" CG3529 16-Dec-15 2015_12 "ENSDARG00000009217(tom1l2),ENSDARG00000056394" "YHR108W(GGA2),YDR358W(GGA1)" WBGene00015561(C07A12.7) ENSXETG00000012156(TOM1L2) "ENSMUSG00000000538(Tom1l2),ENSMUSG00000037827(Gm5884),ENSMUSG00000042870(Tom1)" "ENSG00000100284(TOM1),ENSG00000175662(TOM1L2)" "viable,fertile" DRSC25300 K -0.25227707 0.619442887 -0.236507331 -0.832990081 1.618489585 -0.615156216 FBgn0262512 Vha14-1 Vacuolar H+ ATPase 14kD subunit 1 http://flybase.net/reports/FBgn0262512.html "FBgn0010426, FBgn0065488" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" "0015991=ATP hydrolysis coupled proton transport, 0015992=proton transport" "0033181=plasma membrane proton-transporting V-type ATPase complex, 0005886=plasma membrane, 0000221=vacuolar proton-transporting V-type ATPase, V1 domain" "vha14, CG8210, vha14-1, l(2)SH1248, Vacuolar H[+] ATPase 14kD subunit, F subunit, Vha14, VAF1_DROME, l(2)SH2 1248, V-ATPase proton pump, ATPase, V-ATPase 14kD subunit, ATP6V1F, Vacuolar H[+] ATPase subunit 14-1, unnamed, lethal (2) SH1248" "IPR008218=ATPase, V1 complex, subunit F, IPR005772=ATPase, V1 complex, subunit F, eukaryotic" CG8210 16-Dec-15 2015_12 ENSDARG00000045543(atp6v1f) YGR020C(VMA7) WBGene00006918(vha-9) ENSXETG00000025422(Q6DIZ5_XENTR) ENSMUSG00000004285(Atp6v1f) ENSG00000128524(ATP6V1F) " adult stage , adult stage | female , adult stage | male , embryonic stage -- adult stage " " adult abdomen

, adult head

, adult thorax

" FBgn0036806 Cyp12c1 Cyp12c1 http://flybase.net/reports/FBgn0036806.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process 0005739=mitochondrion "CG4120, cyp12c1, 12c1" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG4120 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039852 nyo nyobe http://flybase.net/reports/FBgn0039852.html FBgn0025950 protein_coding_gene "0016476=regulation of embryonic cell shape, 0003383=apical constriction" 0016021=integral component of membrane "CG1499, anon-EST:Liang-2.47, clone 2.47, nyobe, nyo" "IPR001507=Zona pellucida domain, IPR003609=PAN/Apple domain" CG1499 16-Dec-15 2015_12 "WBGene00009541(cutl-17),WBGene00018256(cutl-28)" "viable,visible,partially lethal - majority die,some die during pupal stage" "denticle,wing" FBgn0029879 APC7 Anaphase Promoting Complex subunit 7 http://flybase.net/reports/FBgn0029879.html protein_coding_gene 0090302=APC-Cdc20 complex activity "0045842=positive regulation of mitotic metaphase/anaphase transition, 0007067=mitotic nuclear division" 0005680=anaphase-promoting complex "Apc7, APC7, Anaphase Promoting Complex 7, CG14444, Anaphase promoting complex 7" "IPR001440=Tetratricopeptide repeat 1, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG14444 16-Dec-15 2015_12 ENSDARG00000063005(LOC558402) ENSXETG00000020941(anapc7) ENSMUSG00000029466(Anapc7) ENSG00000196510(ANAPC7) "viable,fertile" FBgn0267796 CG46121 http://flybase.net/reports/FBgn0267796.html "FBgn0036013, FBgn0036017" protein_coding_gene 0016021=integral component of membrane "CG14177, CG3280" IPR012496=TMC CG46121 16-Dec-15 2015_12 "ENSDARG00000052723(LOC567793),ENSDARG00000056386(LOC567237)" "WBGene00020490(T13G4.3),WBGene00015177(B0416.1)" "ENSXETG00000019616(),ENSXETG00000014406()" ENSMUSG00000038540(Tmc3) ENSG00000188869(TMC3) FBgn0029067 Dd Dullard http://flybase.net/reports/FBgn0029067.html "FBgn0031173, FBgn0063165, FBgn0066839" protein_coding_gene 0004722=protein serine/threonine phosphatase activity "0006998=nuclear envelope organization, 0006470=protein dephosphorylation, 0007474=imaginal disc-derived wing vein specification, 0010867=positive regulation of triglyceride biosynthetic process, 0030514=negative regulation of BMP signaling pathway" "0005737=cytoplasm, 0071595=Nem1-Spo7 phosphatase complex, 0031965=nuclear membrane, 0005635=nuclear envelope, 0005789=endoplasmic reticulum membrane" "BcDNA:LD08201, l(1)G0269, ddd, CG1696, 20151539, anon-WO03040301.167, lethal (1) G0269, d-dullard" "IPR023214=HAD-like domain, IPR011948=Dullard phosphatase domain, eukaryotic, IPR004274=FCP1 homology domain" CG1696 16-Dec-15 2015_12 "ENSDARG00000016519(dullard),ENSDARG00000035781(dullardl)" WBGene00018474(scpl-2) ENSXETG00000006637(dullard) ENSMUSG00000018559(Dullard) ENSG00000175826(CTDNEP1) "partially lethal - majority die,recessive,lethal,viable" "wing,anterior crossvein,ectopic,posterior crossvein,wing vein L2,wing vein L3,heat sensitive,wing vein L4,wing vein L5,endoplasmic reticulumen-e16E,lipid particleen-e16E,wing vein" FBgn0025635 CG17829 http://flybase.net/reports/FBgn0025635.html FBgn0029530 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding" EG:115C2.6 "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG17829 16-Dec-15 2015_12 "ENSDARG00000004851(hinfp),ENSDARG00000069479(LOC100333511),ENSDARG00000037405(zgc:112083)" WBGene00009553(F39B2.1) ENSXETG00000024631(mizf) ENSMUSG00000032119(Hinfp) ENSG00000172273(HINFP) viable DRSC18484 I 1.924853291 0.10449954 0.145089788 0.098309319 -0.333545429 1.047433407 FBgn0013995 Calx Na/Ca-exchange protein http://flybase.net/reports/FBgn0013995.html FBgn0020315 protein_coding_gene "0005509=calcium ion binding, 0005432=calcium:sodium antiporter activity" "0007602=phototransduction, 0055085=transmembrane transport, 0006816=calcium ion transport, 0034976=response to endoplasmic reticulum stress" "0005886=plasma membrane, 0016021=integral component of membrane" "CALX, NCX, Ncx, CALX1.1, calX, Dmel/Ncx, unnamed, CalX, CG5685, calx, 9C5, anon-93ABa" "IPR004837=Sodium/calcium exchanger membrane region, IPR003644=Na-Ca exchanger/integrin-beta4, IPR004836=Sodium/calcium exchanger protein" CG5685 16-Dec-15 2015_12 "ENSDARG00000013422(slc8a1a),ENSDARG00000043406(slc8a1b),ENSDARG00000004931(slc8a3),ENSDARG00000037145(slc8a4b),ENSDARG00000040625(slc8a2b),ENSDARG00000008912(slc8a2a)" "WBGene00003566(ncx-1),WBGene00003567(ncx-2)" "ENSXETG00000002790(SLC8A2),ENSXETG00000007204()" "ENSMUSG00000079055,ENSMUSG00000054640(Slc8a1),ENSMUSG00000030376(Slc8a2)" "ENSG00000100678(SLC8A3),ENSG00000183023(SLC8A1),ENSG00000118160(SLC8A2)" " adult stage , embryonic stage " " adult head

, optic nerve

,

ubiquitous , adult brain

, retina

" "neurophysiology defective,viable,neuroanatomy defective" "eye,eye photoreceptor cell,rhabdomere" DRSC21850 E 0.785693573 -0.145199557 2.092255596 0.906851185 0.201197369 -0.065564438 FBgn0086356 tum tumbleweed http://flybase.net/reports/FBgn0086356.html "FBgn0028559, FBgn0033881" protein_coding_gene "0004871=signal transducer activity, 0019992=diacylglycerol binding, 0005096=GTPase activator activity" "0032465=regulation of cytokinesis, 0001709=cell fate determination, 0051298=centrosome duplication, 0030178=negative regulation of Wnt signaling pathway, 0070507=regulation of microtubule cytoskeleton organization, 0034613=cellular protein localization, 0000281=mitotic cytokinesis, 0007266=Rho protein signal transduction, 0007525=somatic muscle development, 0008283=cell proliferation, 0032507=maintenance of protein location in cell, 0022008=neurogenesis, 0090307=mitotic spindle assembly, 0048813=dendrite morphogenesis, 0007052=mitotic spindle organization, 0048666=neuron development, 0030111=regulation of Wnt signaling pathway" "0005634=nucleus, 0005819=spindle, 0048471=perinuclear region of cytoplasm, 0055028=cortical microtubule, 0030496=midbody" "13345, RhoGAP-50C14, RacGAP50c, TUM, tumbleweed, racGAP50c, DRacGAP, Tumbleweed, RacGap, RacGAP50C, enhancer of naked, acGAP, RacGAP, eon, i249, racGAP50, CG13345, racGAP50C, AcGAP, RacGap50C" "IPR000198=Rho GTPase-activating protein domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008936=Rho GTPase activation protein" CG13345 16-Dec-15 2015_12 "ENSDARG00000015460(racgap1),ENSDARG00000055934" ENSXETG00000013383(racgap1) ENSMUSG00000023015(Racgap1) ENSG00000161800(RACGAP1) " , embryonic stage | embryonic cycle 16 " " cell

, organism

" FBgn0030420 CG12717 http://flybase.net/reports/FBgn0030420.html protein_coding_gene 0016929=SUMO-specific protease activity "0007476=imaginal disc-derived wing morphogenesis, 0016926=protein desumoylation, 0060997=dendritic spine morphogenesis, 0021952=central nervous system projection neuron axonogenesis" "0005634=nucleus, 0005737=cytoplasm" "IPR003653=Ulp1 protease family, C-terminal catalytic domain" CG12717 16-Dec-15 2015_12 ENSXETG00000003609(senp6) ENSMUSG00000052917(Senp7) ENSG00000112701(SENP6) viable DRSC19494 I 1.620592791 -0.573786923 0.221785968 -0.113833208 0.829154151 0.288318323 FBgn0036264 CG11529 http://flybase.net/reports/FBgn0036264.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0022008=neurogenesis" "148640_at, SP84" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG11529 16-Dec-15 2015_12 "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" FBgn0033468 CG1418 http://flybase.net/reports/FBgn0033468.html protein_coding_gene 0017137=Rab GTPase binding IPR004895=Prenylated rab acceptor PRA1 CG1418 16-Dec-15 2015_12 ENSDARG00000004171(rabac1) YNL044W(YIP3) ENSXETG00000023854(RABAC1) ENSMUSG00000003380(Rabac1) ENSG00000105404(RABAC1) viable FBgn0015618 Cdk8 Cyclin-dependent kinase 8 http://flybase.net/reports/FBgn0015618.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0001104=RNA polymerase II transcription cofactor activity, 0004693=cyclin-dependent protein serine/threonine kinase activity" "0036011=imaginal disc-derived leg segmentation, 0000278=mitotic cell cycle, 0007411=axon guidance, 0045498=sex comb development, 0006468=protein phosphorylation, 0022416=chaeta development, 0034472=snRNA 3'-end processing, 0007095=mitotic G2 DNA damage checkpoint, 0006367=transcription initiation from RNA polymerase II promoter" "0005634=nucleus, 0016592=mediator complex" "dCdk8, CDK8, cdk8, DmCdk8, dTRAP56, CG10572, p58" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site" CG10572 16-Dec-15 2015_12 ENSDARG00000016496(cdk8) YPL042C(SSN3) WBGene00000409(cdk-8) ENSXETG00000021324(CDC2L6) "ENSMUSG00000029635(Cdk8),ENSMUSG00000038481(Cdk19)" "ENSG00000132964(CDK8),ENSG00000155111(CDK19)" "neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,viable,visible" "leg,somatic clone - Minute background,sex comb tooth,somatic clone,prothoracic tarsal segment,mesothoracic bristle,mesothoracic tergum" DRSC11113 K -0.414466901 1.103892674 -1.083086244 -0.286429485 1.341834692 2.509891507 FBgn0026376 Rgl Ral guanine nucleotide dissociation stimulator-like ortholog (M. musculus) http://flybase.net/reports/FBgn0026376.html FBgn0036385 protein_coding_gene "0017016=Ras GTPase binding, 0008321=Ral guanyl-nucleotide exchange factor activity" "0046578=regulation of Ras protein signal transduction, 0090630=activation of GTPase activity" "Ral guanine nucleotide exchange factor 2, CG8865, RalGDS, Ral guanine nucleotide exchange factor, DRgl, dRGL, RasGDS, rgl" "IPR029071=Ubiquitin-related domain, IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR000159=Ras-associating (RA) domain, IPR023578=Ras guanine nucleotide exchange factor domain, IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR019804=Ras guanine-nucleotide exchange factor, conserved site" CG8865 16-Dec-15 2015_12 "ENSDARG00000005989(rgl1),ENSDARG00000042409(LOC799483),ENSDARG00000071213(LOC100149956)" WBGene00017891(rgl-1) "ENSXETG00000006267(),ENSXETG00000016747(RGL3)" "ENSMUSG00000026482(Rgl1),ENSMUSG00000026821(Ralgds),ENSMUSG00000040146(Rgl3)" "ENSG00000143344(RGL1),ENSG00000160271(RALGDS)" "viable,fertile,visible,lethal" "tormogen cell,eye,ommatidium,wing,wing vein,macrochaeta" FBgn0038680 Cyp12a5 Cyp12a5 http://flybase.net/reports/FBgn0038680.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process 0005739=mitochondrion "cytochrome P450, 12a5, CG11821" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG11821 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" viable FBgn0028863 CG4587 http://flybase.net/reports/FBgn0028863.html protein_coding_gene 0005245=voltage-gated calcium channel activity "BG:DS07108.2, mdcds_3066, DS07108.2" "IPR002035=von Willebrand factor, type A, IPR013608=VWA N-terminal, IPR013680=Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region, IPR004010=Cache domain" CG4587 16-Dec-15 2015_12 "ENSDARG00000045204,ENSDARG00000025665,ENSDARG00000026855(cacna2d4a),ENSDARG00000023886(LOC100150428)" WBGene00006772(unc-36) ENSXETG00000000081(CACNA2D2) "ENSMUSG00000021991(Cacna2d3),ENSMUSG00000041460(Cacna2d4)" "ENSG00000157445(CACNA2D3),ENSG00000151062(CACNA2D4)" "partially lethal - majority die,some die during pupal stage,viable" FBgn0032395 CG6734 http://flybase.net/reports/FBgn0032395.html protein_coding_gene 0016230=sphingomyelin phosphodiesterase activator activity cg6734 "IPR000409=BEACH domain, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG6734 16-Dec-15 2015_12 WBGene00018672(F52C9.1) ENSMUSG00000045374(Wdr81) ENSG00000167716(WDR81) FBgn0032200 CG5676 http://flybase.net/reports/FBgn0032200.html FBgn0029510 protein_coding_gene "BEST:LD31953, LD31953" IPR007014=FUN14 CG5676 16-Dec-15 2015_12 "ENSDARG00000003442,ENSDARG00000040822(fundc1)" WBGene00011528(T06D8.7) "ENSMUSG00000031198(Fundc2),ENSMUSG00000074620(Gm10731),ENSMUSG00000074619(1700034I23Rik),ENSMUSG00000025040(Fundc1)" "ENSG00000069509(FUNDC1),ENSG00000165775(FUNDC2),ENSG00000182814" "partially lethal - majority die,some die during pupal stage" FBgn0035866 Arl5 ADP-ribosylation factor-like 5 http://flybase.net/reports/FBgn0035866.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0007264=small GTPase mediated signal transduction, 0042147=retrograde transport, endosome to Golgi, 0000042=protein targeting to Golgi" 0005802=trans-Golgi network "Q9VSG8, CG7197" "IPR024156=Small GTPase superfamily, ARF type, IPR006689=Small GTPase superfamily, ARF/SAR type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain" CG7197 16-Dec-15 2015_12 "ENSDARG00000018627(arl5a),ENSDARG00000068512(arl8)" WBGene00000189(arl-5) "ENSXETG00000021692(ARL5A),ENSXETG00000022765(arl8)" "ENSMUSG00000017418(Arl5b),ENSMUSG00000036093(Arl5a)" "ENSG00000165997(ARL5B),ENSG00000162980(ARL5A)" viable FBgn0002023 Lim3 Lim3 http://flybase.net/reports/FBgn0002023.html FBgn0032756 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0008270=zinc ion binding" "0008045=motor neuron axon guidance, 0006355=regulation of transcription, DNA-templated, 0051726=regulation of cell cycle, 0007399=nervous system development" 0005634=nucleus "CG10699, CG15174, lim3, Lim-3A, l(2)Bd, lethal(2)37Bd, l(2)37Bd" "IPR001781=Zinc finger, LIM-type, IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG10699 16-Dec-15 2015_12 ENSDARG00000039458(si:dkeyp-35f11.3) "YDR379W(RGA2),YOR127W(RGA1)" ENSXETG00000000726(LHX3) "ENSMUSG00000026934(Lhx3),ENSMUSG00000026468" "ENSG00000107187(LHX3),ENSG00000121454(LHX4)" " embryonic stage | stage 14 , embryonic stage | stage >=12 , embryonic stage | stage 12 " " embryonic neuron | subset

, embryonic peripheral nervous system | restricted

, RP neuron

, ventral nerve cord | restricted

, embryonic/larval proventriculus

, dorsal vessel primordium

, embryonic brain | restricted

, larval alary muscle | precursor

" "lethal - all die before end of larval stage,recessive,some die during larval stage,short lived,partially lethal - majority die,lethal,neuroanatomy defective,dominant,viable" "cuticle & abdomen & pharate adult,cuticle & thorax & pharate adult,cuticle & head & pharate adult,melanotic mass,transverse nerve,intersegmental nerve,abdominal intersegmental nerve,abdominal segmental nerve" FBgn0263351 AP-2ë_ "Adaptor Protein complex 2, ë_ subunit" http://flybase.net/reports/FBgn0263351.html "FBgn0024832, FBgn0025529, FBgn0046487, FBgn0260567" protein_coding_gene 0008565=protein transporter activity "0007269=neurotransmitter secretion, 0016183=synaptic vesicle coating, 0006901=vesicle coating, 0033227=dsRNA transport, 0006886=intracellular protein transport, 0006897=endocytosis, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development" "0030135=coated vesicle, 0008021=synaptic vesicle, 0030122=AP-2 adaptor complex" "AP-50, anon-EST:Posey50, mu2, CG7057, cg7057, adaptor protein complex 2, anon-WO0172774.104, apm4, mu2 medium chain of adaptin AP2, MENE (3R)-D, AP2mu2, AP50, Dmu2, MENE(3R)-D, AP-2mu" "IPR001392=Clathrin adaptor, mu subunit, IPR022775=AP complex, mu/sigma subunit, IPR018240=Clathrin adaptor, mu subunit, conserved site, IPR028565=Mu homology domain, IPR011012=Longin-like domain" CG7057 16-Dec-15 2015_12 "ENSDARG00000033899(ap2m1b),ENSDARG00000002790(ap2m1a)" WBGene00001082(dpy-23) ENSXETG00000017276(ap2m1) ENSMUSG00000022841(Ap2m1) ENSG00000161203(AP2M1) " embryonic stage | stage >=13 , embryonic stage | stage >=9 , embryonic stage | stage 13 , embryonic stage -- adult stage " " embryonic central nervous system

, embryonic neuroblast

, gastric caecum

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, embryonic/larval midgut

" DRSC14090 IE 0.459302835 1.511244517 0.470415368 1.944734895 -0.778440009 -0.198620924 FBgn0032693 Cyp310a1 Cyp310a1 http://flybase.net/reports/FBgn0032693.html FBgn0019863 protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding, 0005506=iron ion binding" "0030178=negative regulation of Wnt signaling pathway, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "310a1, H, cyp310a1, Cyp310a, anon-EST:CL1d7, Cyp310, CG10391, cytochrome P450" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG10391 16-Dec-15 2015_12 "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" " embryonic stage | stage >5 , embryonic stage | stage 13 , embryonic stage | stage 5 " " mesoderm

, embryonic/larval fat body

, mesoderm anlage

" FBgn0053843 His1:CG33843 His1:CG33843 http://flybase.net/reports/FBgn0053843.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33843 "IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain" CG33843 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0027951 MTA1-like Metastasis associated 1-like http://flybase.net/reports/FBgn0027951.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003682=chromatin binding, 0043565=sequence-specific DNA binding, 0008270=zinc ion binding" "0006909=phagocytosis, 0006355=regulation of transcription, DNA-templated" "0000118=histone deacetylase complex, 0005654=nucleoplasm, 0016581=NuRD complex" "MTA1, MTA, metastasis-associated-1-like-protein, dMTA1-like, MTA1-like, dMTA, CG2244, MTA-like, p120, dMTA-1" "IPR007087=Zinc finger, C2H2, IPR017884=SANT domain, IPR000679=Zinc finger, GATA-type, IPR000949=ELM2 domain, IPR001025=Bromo adjacent homology (BAH) domain, IPR009057=Homeodomain-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR001005=SANT/Myb domain, IPR015880=Zinc finger, C2H2-like" CG2244 16-Dec-15 2015_12 "ENSDARG00000054903(mta3),ENSDARG00000007198(LOC794477),ENSDARG00000013031(mta2)" WBGene00003025(lin-40) "ENSXETG00000017948(Q5U4R0_XENTR),ENSXETG00000005633(MTA2)" "ENSMUSG00000055817(Mta3),ENSMUSG00000021144(Mta1),ENSMUSG00000071646(Mta2)" "ENSG00000182979(MTA1),ENSG00000057935(MTA3),ENSG00000149480(MTA2)" "viable,fertile,visible" mesothoracic tergum FBgn0035143 Ppm1 Ppm1 http://flybase.net/reports/FBgn0035143.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0043169=cation binding" 0006470=protein dephosphorylation "PP2C, dPPM1, CG12169" "IPR000222=PPM-type phosphatase, divalent cation binding, IPR015655=Protein phosphatase 2C, IPR001932=PPM-type phosphatase domain" CG12169 16-Dec-15 2015_12 "YBL056W(PTC3),YER089C(PTC2)" WBGene00011953(T23F11.1) viable DRSC08260 I 1.75199879 0.905614147 1.383013034 0.908599763 0.882381091 0.626929785 FBgn0025825 HDAC3 Histone deacetylase 3 http://flybase.net/reports/FBgn0025825.html FBgn0037331 protein_coding_gene "0005515=protein binding, 0004407=histone deacetylase activity" "0006355=regulation of transcription, DNA-templated, 0006342=chromatin silencing, 0016573=histone acetylation, 0043066=negative regulation of apoptotic process, 0016575=histone deacetylation, 0016049=cell growth" "0005737=cytoplasm, 0005634=nucleus" "hdac3, dHDAC3, CG2128, HDAC3, HDAC, histone deacetylase 3, dmHDA402, Histone Deacetylase-3, Hdac3, Hdac 3, DHDAC3, DmHDAC3, Dromel_CG2128_FBtr0078767_hdac3_mORF" "IPR003084=Histone deacetylase, IPR000286=Histone deacetylase superfamily, IPR023801=Histone deacetylase domain" CG2128 16-Dec-15 2015_12 ENSDARG00000037514(hdac3) ENSXETG00000002708(hdac3) ENSMUSG00000024454(Hdac3) ENSG00000171720(HDAC3) "visible,dominant,neuroanatomy defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell growth,partially lethal,small body,lethal - all die during larval stage,large body,increased cell death" "wing,wing vein,ectopic,projection neuron,somatic clone,eye,ommatidium,embryonic/larval fat body,imaginal disc" FBgn0034065 Rrp42 Rrp42 http://flybase.net/reports/FBgn0034065.html "FBgn0027735, FBgn0027755" protein_coding_gene 0000175=3'-5'-exoribonuclease activity "0022008=neurogenesis, 0006397=mRNA processing" "0000176=nuclear exosome (RNase complex), 0005634=nucleus, 0005737=cytoplasm, 0005652=nuclear lamina" "anon-EST:Posey187, anon-EST:Posey140, CG8395, dRrp42" "IPR001247=Exoribonuclease, phosphorolytic domain 1, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR027408=PNPase/RNase PH domain, IPR015847=Exoribonuclease, phosphorolytic domain 2" CG8395 16-Dec-15 2015_12 ENSDARG00000043336 WBGene00009289(exos-7) ENSXETG00000020144(exosc7) ENSMUSG00000025785(Exosc7) ENSG00000075914(EXOSC7) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0266757 mfr misfire http://flybase.net/reports/FBgn0266757.html "FBgn0035935, FBgn0044828" protein_coding_gene "0007283=spermatogenesis, 0045995=regulation of embryonic development, 0035045=sperm plasma membrane disassembly, 0016079=synaptic vesicle exocytosis, 0030381=chorion-containing eggshell pattern formation, 0009566=fertilization, 0048240=sperm capacitation, 0007343=egg activation" 0008021=synaptic vesicle "CG5747, Otoferlin" IPR000008=C2 domain CG5747 16-Dec-15 2015_12 "ENSDARG00000006112(zgc:63504),ENSDARG00000007370(dysf),ENSDARG00000017128(LOC559066),ENSDARG00000030832(otof),ENSDARG00000020581(LOC100331283)" WBGene00001414(fer-1) "ENSXETG00000003734(),ENSXETG00000021067(),ENSXETG00000009898(),ENSXETG00000003330(OTOF),ENSXETG00000007424()" "ENSMUSG00000062372(Otof),ENSMUSG00000013338(Fer1l4),ENSMUSG00000033788(Dysf),ENSMUSG00000048612(Myof),ENSMUSG00000037106" "ENSG00000214814(FER1L6),ENSG00000115155(OTOF),ENSG00000135636(DYSF),ENSG00000138119(MYOF)" FBgn0039821 CG15556 http://flybase.net/reports/FBgn0039821.html "FBgn0046565, FBgn0046566" protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "anon-WO0170980.178, anon-WO0170980.179, AT07595p" "IPR017981=GPCR, family 2-like, IPR000832=GPCR, family 2, secretin-like" CG15556 16-Dec-15 2015_12 "ENSDARG00000041399,ENSDARG00000041404,ENSDARG00000056062,ENSDARG00000013653(zgc:63629),ENSDARG00000026313,ENSDARG00000069356(id:ibd2808),ENSDARG00000058809" "ENSMUSG00000039116(Gpr126),ENSMUSG00000053852(Gpr112)" ENSG00000144820(GPR128) "viable,fertile" DRSC15094 I 0.181237638 4.149544708 -0.474086385 0.493464759 0.371373885 1.120189009 FBgn0261794 kcc kazachoc http://flybase.net/reports/FBgn0261794.html "FBgn0086754, FBgn0027189, FBgn0025698, FBgn0034929, FBgn0034930, FBgn0066124" protein_coding_gene "0015379=potassium:chloride symporter activity, 0015171=amino acid transmembrane transporter activity" "0006810=transport, 0003333=amino acid transmembrane transport, 0007638=mechanosensory behavior, 0009612=response to mechanical stimulus" "0005886=plasma membrane, 0030424=axon, 0043025=neuronal cell body, 0016021=integral component of membrane" "CK01510, Line J, lethal (2) 60A-C, mdcds_17605, l(2)60A-C, BEST:CK01510, CG2768, CG5594, KCC, E(sda)J, unnamed" "IPR000076=K/Cl co-transporter, IPR004842=SLC12A transporter family, IPR018491=SLC12A transporter, C-terminal, IPR004841=Amino acid permease/ SLC12A domain" CG5594 16-Dec-15 2015_12 "ENSDARG00000014378,ENSDARG00000062058(sb:cb734)" WBGene00019205(kcc-2) ENSXETG00000005430(SLC12A4) "ENSMUSG00000027130(Slc12a6),ENSMUSG00000017765(Slc12a4),ENSMUSG00000017740(Slc12a5),ENSMUSG00000017756(Slc12a7)" "ENSG00000124067(SLC12A4),ENSG00000140199(SLC12A6),ENSG00000113504(SLC12A7),ENSG00000124140(SLC12A5)" FBgn0011834 Ser6 Serine protease 6 http://flybase.net/reports/FBgn0011834.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis "CG2071, SP47, serine protease 6" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG2071 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" viable FBgn0064126 CG33722 http://flybase.net/reports/FBgn0064126.html "FBgn0037557, FBgn0051188, FBgn0053722, FBtr0081799, FBtr0081800, FBpp0081296, FBtr0081801, FBtr0081802, FBpp0081298" protein_coding_gene "CG31188, unnamed, CG18238, CG31188-ORFA" "IPR001012=UBX domain, IPR029071=Ubiquitin-related domain, IPR021569=TUG ubiquitin-like domain" CG33722 16-Dec-15 2015_12 YMR067C(UBX4) WBGene00007100(B0024.10) ENSXETG00000003002(aspscr1) ENSMUSG00000025142(Aspscr1) ENSG00000169696(ASPSCR1) "viable,fertile" FBgn0035665 Jon65Aiii Jonah 65Aiii http://flybase.net/reports/FBgn0035665.html "FBgn0001286, FBgn0025329, FBgn0044570" protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" 0006508=proteolysis "CG6484, Jon65A, CG6483, SP98, anon-WO0140519.59, jon65Aiii, anon-EST:GressD16, Jonah 65, Jonah 65A, Jon65" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG6483 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0051632 sens-2 senseless-2 http://flybase.net/reports/FBgn0051632.html "FBgn0031862, FBgn0031863" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "CG11243, CG17373, sens2, D.m Sens-2, CG31632, Sens-2" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR001878=Zinc finger, CCHC-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG31632 16-Dec-15 2015_12 "ENSDARG00000057232,ENSDARG00000068988,ENSDARG00000069957,ENSDARG00000052780,ENSDARG00000071535,ENSDARG00000071534,ENSDARG00000032285(zgc:113294),ENSDARG00000053192(zgc:112399),ENSDARG00000069796(zgc:113407),ENSDARG00000053165(zgc:113377),ENSDARG00000057324,ENSDARG00000053695(zgc:162948),ENSDARG00000069869(LOC100149696),ENSDARG00000040141,ENSDARG00000023496,ENSDARG00000069868,ENSDARG00000040144(LOC100330452),ENSDARG00000063697,ENSDARG00000071862(si:dkeyp-53d3.3)" ENSG00000162676(GFI1) "viable,visible" trichogen cell FBgn0038546 CG7379 http://flybase.net/reports/FBgn0038546.html protein_coding_gene 0008270=zinc ion binding 0016568=chromatin modification 0070822=Sin3-type complex ING1 "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR019787=Zinc finger, PHD-finger, IPR024610=Inhibitor of growth protein, N-terminal histone-binding, IPR028651=ING family, IPR019786=Zinc finger, PHD-type, conserved site" CG7379 16-Dec-15 2015_12 "ENSDARG00000013042(ing2),ENSDARG00000019116(ing1)" "ENSXETG00000008212(ING1),ENSXETG00000019052(ing2)" "ENSMUSG00000045969(Ing1),ENSMUSG00000063049(Ing2)" "ENSG00000168556(ING2),ENSG00000153487(ING1)" "viable,visible" trichogen cell DRSC24324 K -0.474283439 0.088260455 -0.048829438 0.252400351 0.125861456 2.318656804 FBgn0035640 mad2 mad2 http://flybase.net/reports/FBgn0035640.html protein_coding_gene "0007094=mitotic spindle assembly checkpoint, 1901673=regulation of mitotic spindle assembly, 0007346=regulation of mitotic cell cycle, 0090266=regulation of mitotic cell cycle spindle assembly checkpoint, 0007093=mitotic cell cycle checkpoint, 0000278=mitotic cell cycle, 0051276=chromosome organization" "0005828=kinetochore microtubule, 0005634=nucleus, 0005819=spindle, 1990047=spindle matrix, 0072686=mitotic spindle, 0005737=cytoplasm, 0000776=kinetochore, 0005635=nuclear envelope, 0005875=microtubule associated complex, 0005654=nucleoplasm, 0000922=spindle pole, 0005643=nuclear pore" "CG17498, MAD2, Mad2" "IPR027097=Mitotic spindle checkpoint protein Mad2, IPR003511=HORMA domain" CG17498 16-Dec-15 2015_12 ENSDARG00000004713(mad2l1) YJL030W(MAD2) WBGene00003161(mdf-2) ENSXETG00000002100() ENSMUSG00000029910(Mad2l1) ENSG00000164109(MAD2L1) "mitotic cell cycle defective,developmental rate defective,viable,fertile,cell cycle defective,lethal" embryonic/larval brain FBgn0033289 CG2121 http://flybase.net/reports/FBgn0033289.html FBgn0033290 protein_coding_gene 0003009=skeletal muscle contraction CG8698 "IPR010291=Ion channel regulatory protein, UNC-93, IPR020846=Major facilitator superfamily domain" CG2121 16-Dec-15 2015_12 WBGene00006822(unc-93) viable FBgn0039828 CG1542 http://flybase.net/reports/FBgn0039828.html protein_coding_gene 0003723=RNA binding 0006364=rRNA processing 0005730=nucleolus IPR008610=Eukaryotic rRNA processing CG1542 16-Dec-15 2015_12 ENSDARG00000054980 YKL172W(EBP2) WBGene00015941(C18A3.3) ENSXETG00000009545(EBNA1BP2) ENSMUSG00000028729(Ebna1bp2) ENSG00000117395(EBNA1BP2) "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0259483 Mob4 http://flybase.net/reports/FBgn0259483.html "FBgn0083172, FBgn0033094" protein_coding_gene 0019901=protein kinase binding "0045886=negative regulation of synaptic growth at neuromuscular junction, 0046579=positive regulation of Ras protein signal transduction, 0048812=neuron projection morphogenesis, 0070374=positive regulation of ERK1 and ERK2 cascade, 0008088=axon cargo transport, 0090307=mitotic spindle assembly, 0000226=microtubule cytoskeleton organization" "0043195=terminal bouton, 0005813=centrosome, 0005829=cytosol" "DMob4, dmob4, CG3403, Mob4, Mps one binder kinase activator-like 4, Dmob4, MOB4" IPR005301=MOB kinase activator family CG3403 16-Dec-15 2015_12 ENSDARG00000056085(mobkl3) WBGene00016238(C30A5.3) ENSXETG00000025118(prei3) ENSMUSG00000025979(Mobkl3) ENSG00000115540(PHOCN) FBgn0000339 cni cornichon http://flybase.net/reports/FBgn0000339.html FBgn0020601 protein_coding_gene "0007314=oocyte anterior/posterior axis specification, 0035556=intracellular signal transduction, 0007310=oocyte dorsal/ventral axis specification, 0009953=dorsal/ventral pattern formation, 0009950=dorsal/ventral axis specification, 0030722=establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification, 0045451=pole plasm oskar mRNA localization, 0007350=blastoderm segmentation, 0006888=ER to Golgi vesicle-mediated transport, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0045450=bicoid mRNA localization, 0009952=anterior/posterior pattern specification, 0016192=vesicle-mediated transport, 0008314=gurken signaling pathway, 0046843=dorsal appendage formation, 0008298=intracellular mRNA localization" "0005887=integral component of plasma membrane, 0016020=membrane" "IV, Cni, anon-35Fe, spindle-G, spnG, CG5855, Cornichon, BG:DS02740.13" IPR003377=Cornichon CG5855 16-Dec-15 2015_12 "ENSDARG00000020311(cnih),ENSDARG00000043662(cnih2),ENSDARG00000014953(si:dkey-1j5.3)" "YGL054C(ERV14),YBR210W(ERV15)" WBGene00011648(T09E8.3) ENSXETG00000012227(cnih) "ENSMUSG00000015759(Cnih),ENSMUSG00000024873(Cnih2)" "ENSG00000100528(CNIH),ENSG00000143786(CNIH3),ENSG00000174871(CNIH2)" " oogenesis stage | stage S1-7 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10 " " germarium

, nurse cell

" "wild-type,lethal,maternal effect,partially lethal - majority die,dorsal/ventral axis specification defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" "oocyte nucleus,egg,dorsal appendage,mesoderm,egg chamber,embryonic epidermis,oocyte,chorion,ectopic,micropyle,maternal effect,eye,ommatidium,interommatidial bristle,ocellar bristle,postvertical bristle,wing vein,wing vein L2" FBgn0011747 Ank Ankyrin http://flybase.net/reports/FBgn0011747.html protein_coding_gene "0005200=structural constituent of cytoskeleton, 0008092=cytoskeletal protein binding" "0007016=cytoskeletal anchoring at plasma membrane, 0007165=signal transduction" "0045169=fusome, 0045170=spectrosome, 0005886=plasma membrane" "Dank1, CG32008, ank, dank1, CG1651, ANK, ankyrin, DAnk1" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR000906=ZU5 domain, IPR011029=Death-like domain, IPR000488=Death domain" CG1651 16-Dec-15 2015_12 "ENSXETG00000015555(ANK2),ENSXETG00000016798(ANK1)" ENSMUSG00000031543(Ank1) ENSG00000029534(ANK1) " embryonic stage , oogenesis stage && adult stage | female " ovary

" adult stage && oogenesis stage | early , adult stage && oogenesis stage , larval stage , embryonic stage&&larval stage&&adult stage " " spectrosome &&of germline stem cell

, follicle cell

,salivary gland

" viable FBgn0017566 ND-75 NADH dehydrogenase (ubiquinone) 75 kDa subunit http://flybase.net/reports/FBgn0017566.html protein_coding_gene "0009055=electron carrier activity, 0003954=NADH dehydrogenase activity, 0051536=iron-sulfur cluster binding, 0008137=NADH dehydrogenase (ubiquinone) activity" "0045333=cellular respiration, 0042773=ATP synthesis coupled electron transport" "0005747=mitochondrial respiratory chain complex I, 0005739=mitochondrion" "NADH-ubiquinone oxidoreductase 75 kDa subunit, NDUFS1, NADH:ubiquinone oxidoreductase 75 kDa subunit, NADH:ubiquinone reductase 75kD subunit precursor, ND75, NADH:ubiquinone reductase 75-kD subunit precursor, NADH ubiquinone oxidoreductase 75 kDa, FBpp0071128, CG2286, NUAM, NADH:ubiquinone reductase 75 kDa subunit" "IPR000283=NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site, IPR010228=NADH:ubiquinone oxidoreductase, subunit G, IPR015405=NADH-quinone oxidoreductase, chain G, C-terminal, IPR019574=NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding, IPR006963=Molybdopterin oxidoreductase, 4Fe-4S domain, IPR012675=Beta-grasp domain, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR006656=Molybdopterin oxidoreductase" CG2286 16-Dec-15 2015_12 ENSDARG00000028546(ndufs1) WBGene00021562(nuo-5) ENSXETG00000010108(NDUFS1) ENSMUSG00000025968(Ndufs1) ENSG00000023228(NDUFS1) increased cell number "lamellocyte | third instar larval stage,lamellocyte | larval stage" FBgn0022382 Pka-R2 "Protein kinase, cAMP-dependent, regulatory subunit type 2" http://flybase.net/reports/FBgn0022382.html "FBgn0000353, FBgn0033472, FBgn0047292" protein_coding_gene "0008603=cAMP-dependent protein kinase regulator activity, 0005515=protein binding" "0045475=locomotor rhythm, 0048149=behavioral response to ethanol, 0006468=protein phosphorylation, 0007623=circadian rhythm, 0007411=axon guidance, 0048148=behavioral response to cocaine, 0001932=regulation of protein phosphorylation, 0007622=rhythmic behavior" "0005737=cytoplasm, 0005952=cAMP-dependent protein kinase complex, 0005886=plasma membrane" "cAMP-dependent protein kinase type II, RII, Cos1, Pka-RII, CG15862, Epaulette, PKA RII, BcDNA:GM01761, PKA-RII, Epa, cos1, Costal-1, pka-RII, costal-1, PKa-R2, Cos, pkA, Costal, RII[[DR]], PKA, Cos-1, protein kinase A, cAMP-dependent protein kinase R2, PKA-R2" "IPR003117=cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, IPR018488=Cyclic nucleotide-binding, conserved site, IPR014710=RmlC-like jelly roll fold, IPR012198=cAMP-dependent protein kinase regulatory subunit, IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like" CG15862 16-Dec-15 2015_12 "ENSDARG00000009477(LOC100329437),ENSDARG00000033184(prkar2aa),ENSDARG00000036446(LOC100331387)" YIL033C(BCY1) "ENSXETG00000009330(PRKAR2A),ENSXETG00000005920(PRKAR2B)" "ENSMUSG00000032601(Prkar2a),ENSMUSG00000002997(Prkar2b)" "ENSG00000114302(PRKAR2A),ENSG00000005249(PRKAR2B)" "viable,fertile,locomotor rhythm defective,chemical resistant,visible,neuroanatomy defective" "ovariole,follicle cell,nurse cell,ectopic,interfollicle cell,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,abdominal segmental nerve,eye,costal cell,wing,haltere,trichogen cell" FBgn0017457 U2af38 U2 small nuclear riboprotein auxiliary factor 38 http://flybase.net/reports/FBgn0017457.html FBgn0010626 protein_coding_gene "0008187=poly-pyrimidine tract binding, 0046872=metal ion binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0008380=RNA splicing, 0000398=mRNA splicing, via spliceosome, 0007052=mitotic spindle organization" "0005686=U2 snRNP, 0005681=spliceosomal complex, 0005634=nucleus, 0071011=precatalytic spliceosome" "dU2AF[38], U2AF 38, U2AF, u2af38, l(2)06751, U2AF38, CG3582, dU2AF38, DU2AF38" "IPR009145=U2 auxiliary factor small subunit, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000571=Zinc finger, CCCH-type" CG3582 16-Dec-15 2015_12 ENSDARG00000015325(u2af1) WBGene00006698(uaf-2) ENSXETG00000004456(U2AF1) ENSMUSG00000061613(U2af1) ENSG00000160201(U2AF1) " adult stage | female , adult stage | male " "lethal,recessive,partially,sterile,visible,partially lethal - majority die,wild-type,lethal - all die before end of larval stage,some die during larval stage" "crystal cell,sex comb,macrochaeta" DRSC00796 I -0.206589956 -1.867011555 -0.704197999 0.092476469 -0.021372329 0.940777771 FBgn0035709 eIF4E-4 eIF4E-4 http://flybase.net/reports/FBgn0035709.html "FBgn0045411, FBgn0046310" protein_coding_gene "0003743=translation initiation factor activity, 0031370=eukaryotic initiation factor 4G binding, 0000340=RNA 7-methylguanosine cap binding, 0005515=protein binding, 0000339=RNA cap binding" 0006413=translational initiation 0016281=eukaryotic translation initiation factor 4F complex "eIF4E, NEST:bs04e06, CG10124, BEST:GH01027, CT28485" "IPR023398=Translation Initiation factor eIF- 4e-like, IPR001040=Translation Initiation factor eIF- 4e, IPR019770=Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG10124 16-Dec-15 2015_12 "ENSDARG00000013274(zgc:101581),ENSDARG00000012274(zgc:110154),ENSDARG00000014565(eif4e1b)" YOL139C(CDC33) WBGene00002061(ife-3) ENSMUSG00000028156(Eif4e) "ENSG00000151247(EIF4E),ENSG00000175766(EIF4E1B)" DRSC09701 IE -0.388960377 -1.711043038 -2.340334546 -0.993394952 -1.437978556 -0.426657049 FBgn0028582 lqf liquid facets http://flybase.net/reports/FBgn0028582.html "FBgn0022808, FBgn0028209, FBgn0062152" protein_coding_gene "0045747=positive regulation of Notch signaling pathway, 0006897=endocytosis, 0006914=autophagy, 0015032=storage protein import into fat body, 0007269=neurotransmitter secretion, 0008593=regulation of Notch signaling pathway, 0048488=synaptic vesicle endocytosis, 0009997=negative regulation of cardioblast cell fate specification" "Epsin1/Liquid facets, dEpsin, LqF, Drosophila epsin, Enhancer of faf bE25, epsin, CG8532, Lqf, 0110/27, Liquid facets, E(faf)bE25, Epsin, l(3)S011027, Epsin 1, anon-WO0118547.239" "IPR003903=Ubiquitin interacting motif, IPR008942=ENTH/VHS, IPR013809=ENTH domain" CG8532 16-Dec-15 2015_12 "ENSDARG00000008377,ENSDARG00000004633" "YLR206W(ENT2),YDL161W(ENT1)" "ENSXETG00000022662(epn2),ENSXETG00000019123(EPN1)" "ENSMUSG00000035203(Epn1),ENSMUSG00000010080(Epn3),ENSMUSG00000001036(Epn2)" "ENSG00000049283(EPN3),ENSG00000063245(EPN1)" larval stage | third instar eye disc

"partially lethal - majority live,developmental rate defective,heat sensitive,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,viable" "nurse cell,heat sensitive,macrochaeta,cardioblast,supernumerary,embryonic/larval fat body,mitochondrial outer membrane,eye photoreceptor cell,somatic clone,mesothoracic tergum & chaeta | supernumerary,A1-7 dorsal acute muscle 1,embryonic somatic muscle,dorsal,retina,wing,wing vein,mesothoracic tergum & macrochaeta | supernumerary | somatic clone,eye photoreceptor cell & ommatidium | ectopic,eye,photoreceptor cell,ectopic,ommatidium,wing margin bristle,tarsal segment,mystery cell,leg sensillum,cell non-autonomous,photoreceptor cell R7,outer photoreceptor cell" DRSC27882 K 0.051745562 0.206104458 0.808185635 0.291004969 2.959109124 0.112070494 FBgn0037580 DppIII Dipeptidyl aminopeptidase III http://flybase.net/reports/FBgn0037580.html protein_coding_gene 0008239=dipeptidyl-peptidase activity 0006508=proteolysis "0016020=membrane, 0005829=cytosol" "dipeptidyl aminopeptidase, CG7415, DPP III, Dipeptidyl-peptidase III, DPP" IPR005317=Dipeptidyl-peptidase 3 CG7415 16-Dec-15 2015_12 ENSDARG00000020676(dpp3) YOL057W() WBGene00008532(F02E9.9) ENSXETG00000020577(DPP3) ENSMUSG00000063904(Dpp3) ENSG00000221844 "viable,fertile" FBgn0025837 CG17636 http://flybase.net/reports/FBgn0025837.html protein_coding_gene 0003840=gamma-glutamyltransferase activity 0006749=glutathione metabolic process EG:23E12.1 "IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000101=Gamma-glutamyltranspeptidase" CG17636 16-Dec-15 2015_12 "ENSDARG00000023526(ggt1),ENSDARG00000018342(LOC569014),ENSDARG00000013504,ENSDARG00000040592" YLR299W(ECM38) "WBGene00011393(T03D8.6),WBGene00019204(H14N18.4),WBGene00012416(Y7A9A.1)" ENSXETG00000004232(BC075461.1) ENSMUSG00000006345(Ggt1) "ENSG00000100031(GGT1),ENSG00000197421,ENSG00000133475(GGT2),ENSG00000216522" FBgn0036566 ClC-c Chloride channel-c http://flybase.net/reports/FBgn0036566.html FBgn0044795 protein_coding_gene "0005247=voltage-gated chloride channel activity, 0005254=chloride channel activity" "0055085=transmembrane transport, 0006821=chloride transport" 0016020=membrane "Clc-c, anon-WO0138359.7, DmClC-c, DmClCc, CG5284" "IPR014743=Chloride channel, core, IPR001807=Chloride channel, voltage gated, IPR000644=CBS domain" CG5284 16-Dec-15 2015_12 "ENSDARG00000003269(wu:fb78c02),ENSDARG00000019693(LOC562336),ENSDARG00000022466(LOC557584),ENSDARG00000035808" YJR040W(GEF1) WBGene00000532(clh-5) "ENSXETG00000023146(CLCN3),ENSXETG00000015727(CLCN4)" "ENSMUSG00000004319(Clcn3),ENSMUSG00000004317(Clcn5),ENSMUSG00000000605(Clcn4-2)" "ENSG00000171365(CLCN5),ENSG00000073464(CLCN4),ENSG00000109572(CLCN3)" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0000079 Amy-p Amylase proximal http://flybase.net/reports/FBgn0000079.html "FBgn0014457, FBgn0035652, FBgn0042197" protein_coding_gene "0003824=catalytic activity, 0043169=cation binding, 0004556=alpha-amylase activity" 0005975=carbohydrate metabolic process 0005576=extracellular region "alpha-Amylase, AmyA, alpha-amylase, Amy, amylase, alpha-AMY, Amy4, Amy2, Amylase-A, CG18730, Amy5, Amy(p), amylase proximal, AMY, Amy1, amy-p, alpha-Amy, CG18640, Amylase, alpha-amylase proximal, Amy-proximal, amy" "IPR015902=Glycoside hydrolase, family 13, IPR017853=Glycoside hydrolase superfamily, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR031319=Alpha-amylase, C-terminal domain, IPR006046=Alpha amylase, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR013781=Glycoside hydrolase, catalytic domain, IPR006048=Alpha-amylase/branching enzyme, C-terminal all beta" CG18730 16-Dec-15 2015_12 "ENSDARG00000013856(amy2a),ENSDARG00000030357(zgc:66313),ENSDARG00000009443(zgc:92137)" WBGene00008220(C50B6.7) "ENSXETG00000010847(),ENSXETG00000010846(amy1a)" "ENSMUSG00000074266(Amy2a3),ENSMUSG00000074268(Amy2a5),ENSMUSG00000079850,ENSMUSG00000074267(Amy2a4),ENSMUSG00000074264(Amy1)" "ENSG00000197839,ENSG00000196318,ENSG00000174876(AMY1B),ENSG00000051415,ENSG00000187733(AMY1C)" adult stage adult midgut

adult stage " midgut

, midgut

{ - mapP00 } , adult midgut

" electrophoretic variant FBgn0052445 CG32445 http://flybase.net/reports/FBgn0052445.html "FBgn0037112, FBgn0044750, FBgn0063606" protein_coding_gene "0030246=carbohydrate binding, 0004034=aldose 1-epimerase activity" 0019318=hexose metabolic process "CG12562, anon-WO0140519.131" "IPR008183=Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013=Galactose mutarotase-like domain, IPR014718=Glycoside hydrolase-type carbohydrate-binding, subgroup, IPR015443=Aldose 1-epimerase" CG32445 16-Dec-15 2015_12 ENSDARG00000057630(galm) "YHR210C(),YNR071C()" WBGene00015270(C01B4.6) ENSXETG00000009022(GALM) ENSMUSG00000035473(Galm) ENSG00000143891(GALM) DRSC11678 E 0.508170854 0.894461997 1.83967461 -1.335382035 0.275878293 0.466984885 FBgn0038826 Syp Syncrip http://flybase.net/reports/FBgn0038826.html "FBgn0010818, FBgn0061828" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding" "0000398=mRNA splicing, via spliceosome, 0046843=dorsal appendage formation, 0007310=oocyte dorsal/ventral axis specification, 0022008=neurogenesis, 0046011=regulation of oskar mRNA translation" "0035770=ribonucleoprotein granule, 0071011=precatalytic spliceosome" "AI945337, syp, cg17838, l(3)03806, anon-WO0118547.613, CG17838" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006535=HnRNP R/Q splicing factor" CG17838 16-Dec-15 2015_12 "ENSDARG00000014569(hnrpr),ENSDARG00000040184(syncrip),ENSDARG00000026723(syncripl)" WBGene00002000(hrp-2) "ENSXETG00000018075(SYNCRIP),ENSXETG00000007102(hnrpr)" "ENSMUSG00000066037(Hnrnpr),ENSMUSG00000032423(Syncrip)" "ENSG00000125944(HNRNPR),ENSG00000135316(SYNCRIP)" "lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "dorsal appendage,germline clone,egg,pole cell,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001994 crp cropped http://flybase.net/reports/FBgn0001994.html "FBgn0024216, FBgn0026860, FBgn0041143, FBgn0065396" protein_coding_gene "0046983=protein dimerization activity, 0043565=sequence-specific DNA binding, 0017022=myosin binding" 0007526=larval somatic muscle development 0005634=nucleus "35F(AT)[[17]], l(2)k00809, l(2)SH1614, unnamed, AP4, dAP-4, l(2)k03505, AP-4, l(2)00232, BG:DS02740.3, MS:35F.AT17, bHLHe63, l(2)35Fd, CG7664, l(2)SH2 1614" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG7664 16-Dec-15 2015_12 WBGene00001955(hlh-11) ENSMUSG00000005718(Tcfap4) ENSG00000090447(TFAP4) " larval stage | third instar ,, embryonic stage " "

, organism | ubiquitous

, salivary gland

" "viable,fertile,lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "wing,eye,leg,trichogen cell,mesothoracic tergum" DRSC03515 IE -1.369710997 7.056391553 2.086493003 0.623990168 -1.355019968 -1.151520313 FBgn0031286 CG3862 http://flybase.net/reports/FBgn0031286.html protein_coding_gene RCC GEF-related protein "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG3862 16-Dec-15 2015_12 ENSDARG00000059583(wbscr16) WBGene00012370(W09G3.7) ENSXETG00000009171(WBSCR16) ENSMUSG00000061979(Wbscr16) ENSG00000174374(WBSCR16) "neuroanatomy defective,viable" anterior fascicle & synapse FBgn0037980 CG3313 http://flybase.net/reports/FBgn0037980.html protein_coding_gene "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG3313 16-Dec-15 2015_12 ENSDARG00000063155(zgc:154031) "ENSMUSG00000028436(Dcaf12),ENSMUSG00000050926(Dcaf12l2),ENSMUSG00000045284(Dcaf12l1)" "ENSG00000198876(DCAF12),ENSG00000198354(DCAF12L2),ENSG00000198889(DCAF12L1)" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0025574 Pli Pellino http://flybase.net/reports/FBgn0025574.html protein_coding_gene 0019207=kinase regulator activity "0008348=negative regulation of antimicrobial humoral response, 0006952=defense response, 0045751=negative regulation of Toll signaling pathway, 0006955=immune response, 1902524=positive regulation of protein K48-linked ubiquitination, 0042325=regulation of phosphorylation, 0007165=signal transduction, 0008063=Toll signaling pathway" "0005886=plasma membrane, 0005737=cytoplasm" "pli, CG5212, PAP, pellino, Pelle associated protein" IPR006800=Pellino family CG5212 16-Dec-15 2015_12 "ENSDARG00000029045(peli2),ENSDARG00000044083(peli1),ENSDARG00000069678,ENSDARG00000043652" WBGene00017766(F25B4.2) "ENSXETG00000012997(PELI1),ENSXETG00000015696(peli2)" "ENSMUSG00000021846(Peli2),ENSMUSG00000020134(Peli1),ENSMUSG00000024901(Peli3)" "ENSG00000139946(PELI2),ENSG00000197329(PELI1),ENSG00000174516(PELI3)" " embryonic stage | 0-2hr , adult stage | female , embryonic stage -- adult stage " " embryonic stage , embryonic stage -- adult stage "

ubiquitous "immune response defective,recessive,lethal - all die before end of P-stage,some die during P-stage,viable" "embryonic head,germline clone,germ band" FBgn0015360 oxt peptide O-xylosyltransferase http://flybase.net/reports/FBgn0015360.html "FBgn0035322, FBgn0052300" protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0030158=protein xylosyltransferase activity" "0042732=D-xylose metabolic process, 0050650=chondroitin sulfate proteoglycan biosynthetic process, 0030206=chondroitin sulfate biosynthetic process, 0030201=heparan sulfate proteoglycan metabolic process, 0030204=chondroitin sulfate metabolic process, 0015012=heparan sulfate proteoglycan biosynthetic process" 0016020=membrane "dOXT, dXylT, CG17771, Peptide-o-xylosyltransferase, Oxt, anon-i2, Drosophila peptide O-xylosyltransferase, CG17772, Peptide-O-xylosyl-transferase, OXT, CG32300" "IPR024448=Xylosyltransferase, IPR003406=Glycosyl transferase, family 14, IPR002889=Carbohydrate-binding WSC" CG32300 16-Dec-15 2015_12 ENSDARG00000061248(xylt1) WBGene00005024(sqv-6) "ENSXETG00000019693(XYLT1),ENSXETG00000006839(xylt2)" "ENSMUSG00000030657(Xylt1),ENSMUSG00000020868(Xylt2)" "ENSG00000103489(XYLT1),ENSG00000015532(XYLT2)" "visible,viable" "eye,ommatidium" FBgn0053846 His1:CG33846 His1:CG33846 http://flybase.net/reports/FBgn0053846.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33846 "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5" CG33846 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0028983 Spn55B Serpin 55B http://flybase.net/reports/FBgn0028983.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0045861=negative regulation of proteolysis, 0030162=regulation of proteolysis, 0010951=negative regulation of endopeptidase activity" 0005615=extracellular space "Spn6, sp6, serpin 6, Spn55B, CG10913, Serine protease inhibitor 6, sp-6, Sp6" "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG10913 16-Dec-15 2015_12 ENSDARG00000034168(serpini1) "ENSXETG00000000624(serpinb1),ENSXETG00000018037(),ENSXETG00000020033(serpinc1)" "ENSMUSG00000044734(Serpinb1a),ENSMUSG00000051029(Serpinb1b),ENSMUSG00000079049(Serpinb1c),ENSMUSG00000044594(Serpinb3a),ENSMUSG00000073602(Serpinb3b),ENSMUSG00000058017(Serpinb3d),ENSMUSG00000067006(Serpinb5),ENSMUSG00000073601(Serpinb3c),ENSMUSG00000059956(Serpinb12),ENSMUSG00000062345(Serpinb2),ENSMUSG00000048775(Serpinb13),ENSMUSG00000026327(Serpinb11),ENSMUSG00000067001(Serpinb7),ENSMUSG00000026715(Serpinc1)" "ENSG00000021355(SERPINB1),ENSG00000170542(SERPINB9),ENSG00000166401(SERPINB8),ENSG00000124570(SERPINB6),ENSG00000197632(SERPINB2),ENSG00000166404,ENSG00000206075(SERPINB5)" "visible,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum DRSC07694 I -1.622734267 -0.030584935 0.021696624 -0.224003217 -0.794897367 -1.150287355 FBgn0033699 RpS11 Ribosomal protein S11 http://flybase.net/reports/FBgn0033699.html "FBgn0025258, FBgn0025784" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0022008=neurogenesis, 0007052=mitotic spindle organization" "0005730=nucleolus, 0022627=cytosolic small ribosomal subunit, 0000228=nuclear chromosome, 0005737=cytoplasm" "anon-MMS23, clone 23, S11, anon-EST:fe1D2, CG8857, anon-fast-evolving-1D2, RPS11, M(2)48E, unnamed" "IPR000266=Ribosomal protein S17, IPR012340=Nucleic acid-binding, OB-fold, IPR019979=Ribosomal protein S17, conserved site, IPR028333=Ribosomal protein S17, archaeal/eukaryotic" CG8857 16-Dec-15 2015_12 ENSDARG00000053058(rps11) "YDR025W(RPS11A),YBR048W(RPS11B)" WBGene00004480(rps-11) "ENSMUSG00000003429(Rps11),ENSMUSG00000046620(Gm9808)" ENSG00000142534(RPS11) "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC22700 IEK 3.994574621 -0.054075813 3.091891144 -0.803494123 1.958534934 3.45436981 FBgn0037728 CG16817 http://flybase.net/reports/FBgn0037728.html protein_coding_gene 0007030=Golgi organization "0031965=nuclear membrane, 0005783=endoplasmic reticulum, 0005634=nucleus" "Homolog to co-chaperone p23, YC17" "IPR008978=HSP20-like chaperone, IPR007052=CS domain" CG16817 16-Dec-15 2015_12 "ENSDARG00000037284(ptges3a),ENSDARG00000058831(zgc:86751),ENSDARG00000036166" YKL117W(SBA1) WBGene00022599(ZC395.10) ENSXETG00000021774(ptges3) ENSMUSG00000071072(Ptges3) ENSG00000110958(PTGES3) "viable,fertile" DRSC27806 K -0.291768891 0.077041335 1.003451211 1.24955133 1.102098879 1.885138397 FBgn0028471 Nab2 http://flybase.net/reports/FBgn0028471.html "FBgn0025989, FBgn0043459" protein_coding_gene "0008143=poly(A) binding, 0046872=metal ion binding" "1900364=negative regulation of mRNA polyadenylation, 0006909=phagocytosis" 0005634=nucleus "anon-EST:Liang-1.43, DnAB2, BEST:GH27517, RE28534, BcDNA:LD27873, clone 1.43, CG5720, dNab2" "IPR000571=Zinc finger, CCCH-type" CG5720 16-Dec-15 2015_12 ENSDARG00000041402(zc3h14) YGL122C(NAB2) WBGene00022019(sut-2) ENSMUSG00000021012(Zc3h14) ENSG00000100722(ZC3H14) "some die during pharate adult stage,majority die during pharate adult stage,locomotor behavior defective,short lived,flight defective,lethal - all die before end of P-stage,viable,visible" "embryonic/larval hemocyte | third instar larval stage,wing,macrochaeta,microchaeta,scutellar bristle,eye" FBgn0250823 gish gilgamesh http://flybase.net/reports/FBgn0250823.html "FBgn0011253, FBgn0038411, FBgn0062017, FBgn0045173" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0009612=response to mechanical stimulus, 0007283=spermatogenesis, 0008347=glial cell migration, 0016055=Wnt signaling pathway, 2001135=regulation of endocytic recycling, 0051126=negative regulation of actin nucleation, 0090175=regulation of establishment of planar polarity, 0007291=sperm individualization, 0016318=ommatidial rotation, 2000039=regulation of trichome morphogenesis, 0008355=olfactory learning" "0005886=plasma membrane, 0070864=sperm individualization complex, 0005634=nucleus" "CKIg-like, CK1, spider, CK1[[gamma]], CG6963, CKIgamma, ms(3)89B, CKI-related, Gish, anon-WO0118547.425, NEST:bs27c08, Hrr25, CK1-gamma, casein kinase 1gamma, CK1gamma, Gilgamesh, Spider" "IPR011009=Protein kinase-like domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR022247=Casein kinase 1 gamma C-terminal, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG6963 16-Dec-15 2015_12 "ENSDARG00000005458(csnk1g2a),ENSDARG00000034056(csnk1g2b),ENSDARG00000033872(csnk1g1)" "YNL154C(YCK2),YHR135C(YCK1),YER123W(YCK3)" WBGene00013709(csnk-1) "ENSXETG00000010259(CSNK1G3),ENSXETG00000006434(csnk1g2)" "ENSMUSG00000032384(Csnk1g1),ENSMUSG00000073563(Csnk1g3),ENSMUSG00000003345(Csnk1g2)" "ENSG00000151292(CSNK1G3),ENSG00000133275(CSNK1G2),ENSG00000169118(CSNK1G1)" DRSC16154 K -0.732371574 -1.476310984 0.773374832 1.3502412 0.283957945 7.73610614 FBgn0024956 Mat1 Menage a trois 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0024956.html protein_coding_gene "0004693=cyclin-dependent protein serine/threonine kinase activity, 0008270=zinc ion binding, 0008353=RNA polymerase II carboxy-terminal domain kinase activity, 0000990=core RNA polymerase binding transcription factor activity" "0006367=transcription initiation from RNA polymerase II promoter, 0007049=cell cycle" "0005675=holo TFIIH complex, 0032806=carboxy-terminal domain protein kinase complex" "CG7614, Mat1, MAT1, AT-1" "IPR001841=Zinc finger, RING-type, IPR004575=Cdk-activating kinase assembly factor MAT1/Tfb3, IPR015877=Cdk-activating kinase assembly factor MAT1, centre, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site" CG7614 16-Dec-15 2015_12 ENSDARG00000002077(mnat1) YDR460W(TFB3) WBGene00018769(mnat-1) ENSXETG00000016938(mnat1) ENSMUSG00000021103(Mnat1) ENSG00000020426(MNAT1) "viable,visible" "trichogen cell,tormogen cell,mesothoracic tergum" FBgn0028717 Lnk Lnk http://flybase.net/reports/FBgn0028717.html "FBgn0039383, FBgn0039384" protein_coding_gene "0035591=signaling adaptor activity, 0004871=signal transducer activity" "0046628=positive regulation of insulin receptor signaling pathway, 0043568=positive regulation of insulin-like growth factor receptor signaling pathway, 0007165=signal transduction, 0060180=female mating behavior, 0038202=TORC1 signaling, 0040008=regulation of growth" 0005886=plasma membrane "CG5908, CG 17367, LNK, CG17367, dSH2B, lnk" "IPR001849=Pleckstrin homology domain, IPR030523=SH2B adapter protein, IPR000980=SH2 domain, IPR015012=Phenylalanine zipper, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG17367 16-Dec-15 2015_12 ENSDARG00000057679(sh2b1) ENSXETG00000005475(SH2B2) "ENSMUSG00000030733(Sh2b1),ENSMUSG00000005057(Sh2b2)" "ENSG00000178188(SH2B1),ENSG00000160999" "short lived,starvation stress response defective,oxidative stress response defective,viable,fertile,small body,decreased cell size,decreased cell number,female sterile,male fertile,long lived,recessive,female semi-sterile,mating defective,visible,somatic clone" "wing blade,wing,egg chamber,head,somatic clone,ommatidium,eye,ovary,oocyte,rhabdomere,wing disc,eye photoreceptor cell" DRSC16729 I -0.53503895 -1.832624049 -0.537402868 -0.947140998 -0.170842185 0.352440767 FBgn0053861 His1:CG33861 His1:CG33861 http://flybase.net/reports/FBgn0053861.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33861 "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5" CG33861 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0033958 CG12858 http://flybase.net/reports/FBgn0033958.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR024989=Major facilitator superfamily associated domain, IPR011701=Major facilitator superfamily" CG12858 16-Dec-15 2015_12 "ENSDARG00000032318(mfsd6a),ENSDARG00000054583" WBGene00020051(R13A5.9) ENSXETG00000015249(MFSD6) ENSMUSG00000041439(Mfsd6) ENSG00000151690(MFSD6) viable FBgn0038466 CG8907 http://flybase.net/reports/FBgn0038466.html protein_coding_gene LP01469p "IPR001452=SH3 domain, IPR013625=Tensin phosphotyrosine-binding domain" CG8907 16-Dec-15 2015_12 "ENSDARG00000058108(LOC798252),ENSDARG00000018440(zgc:56041),ENSDARG00000005704(eps8l3)" "ENSXETG00000003193(EPS8L1),ENSXETG00000022526(EPS8)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033065 Cyp6w1 Cyp6w1 http://flybase.net/reports/FBgn0033065.html FBgn0027077 protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity" "0055114=oxidation-reduction process, 0007608=sensory perception of smell" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CYP6W1, AntP450, Cyp6W1, 6w1, CG8345, cytochrome P450" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG8345 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" adult stage " leg

, adult head

, antennal segment 3

" FBgn0039713 RpS8 Ribosomal protein S8 http://flybase.net/reports/FBgn0039713.html "FBgn0025277, FBgn0025982, FBgn0062869, FBgn0062967" protein_coding_gene 0003735=structural constituent of ribosome "0022008=neurogenesis, 0000462=maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), 0035167=larval lymph gland hemopoiesis, 0006414=translational elongation, 0006412=translation" "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "S8, anon-EST:fe1A2, Rp S8, chr3R:25688477..25688608, Rps8, anon-fast-evolving-1A2, BcDNA:RH06886, BcDNA:SD17528, unnamed, anon-EST:Liang-1.56, CG7808, clone 1.56" "IPR018283=Ribosomal protein S8e, conserved site, IPR022309=Ribosomal protein S8e/ribosomal biogenesis NSA2, IPR001047=Ribosomal protein S8e" CG7808 16-Dec-15 2015_12 "ENSDARG00000055996(rps8),ENSDARG00000057368(zgc:112361)" "YBL072C(RPS8A),YER102W(RPS8B)" WBGene00004477(rps-8) ENSXETG00000013596(rps8) "ENSMUSG00000060198(Gm11353),ENSMUSG00000047675(Rps8),ENSMUSG00000071303(Rps8-ps1),ENSMUSG00000074547,ENSMUSG00000066626(Gm5121)" ENSG00000142937(RPS8) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16318 EK -0.598986188 0.616229562 2.527015525 -3.563896316 1.545768528 2.779666009 FBgn0036728 UQCR-Q Ubiquinol-cytochrome c reductase ubiquinone-binding protein http://flybase.net/reports/FBgn0036728.html FBgn0063337 protein_coding_gene "0048039=ubiquinone binding, 0008121=ubiquinol-cytochrome-c reductase activity" "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" "0005811=lipid particle, 0005750=mitochondrial respiratory chain complex III" "Ubiquinol-cytochrome c reductase Ubiquinone-binding protein QP-C, Ubiquinol-cytochrome C reductase complex ubiquinone-binding protein QP-C, UCRQ, CG7580, Ubiquinol-cytochrome c oxidoreductase Ubiquinone-binding protein QP-C, BcDNA:AT13736, ubiquinone binding protein" IPR004205=Cytochrome b-c1 complex subunit 8 CG7580 16-Dec-15 2015_12 ENSDARG00000029064(uqcrq) "WBGene00019937(R07E4.3),WBGene00009739(F45H10.2)" ENSXETG00000027128(UQCRQ) ENSMUSG00000044894(Uqcrq) ENSG00000164405(UQCRQ) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052679 CG32679 http://flybase.net/reports/FBgn0052679.html protein_coding_gene 0005576=extracellular region "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG32679 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" "viable,fertile" DRSC17644 I 2.606495757 0.949251896 1.126414319 0.128913923 0.954218873 -0.201171419 FBgn0015776 nrv1 nervana 1 http://flybase.net/reports/FBgn0015776.html FBgn0014867 protein_coding_gene "0005515=protein binding, 0005391=sodium:potassium-exchanging ATPase activity, 0008324=cation transmembrane transporter activity" "0006813=potassium ion transport, 0006814=sodium ion transport, 0006812=cation transport" "0005886=plasma membrane, 0005890=sodium:potassium-exchanging ATPase complex" "Nrv, Na,K-ATPase, Na[+]/K[+] ATPase, Na[+]/K[+]-ATPase, CG9258, Nervana, Nirvana, Nervana 1, Na[+]/K[+]ATPase, NKA-alpha, NaK ATPase, unnamed, nervana, 42kDa, Nervous system antigen 1, Nervana1, Nirvana 1, Nrv1" IPR000402=Sodium/potassium-transporting ATPase subunit beta CG9258 16-Dec-15 2015_12 "ENSDARG00000013144(atp1b1a),ENSDARG00000015790(atp1b3a),ENSDARG00000037678(LOC100329243),ENSDARG00000042837(atp1b3b),ENSDARG00000013605(atp1b2a),ENSDARG00000034424(atp1b2b),ENSDARG00000053262(atp1b4)" "WBGene00010117(nkb-3),WBGene00007646(nkb-1)" "ENSXETG00000002414(atp1b1),ENSXETG00000004477(ATP1B4),ENSXETG00000025056(atp1b2)" "ENSMUSG00000026576(Atp1b1),ENSMUSG00000041329(Atp1b2),ENSMUSG00000016327(Atp1b4)" "ENSG00000143153(ATP1B1),ENSG00000129244(ATP1B2),ENSG00000101892(ATP1B4),ENSG00000069849(ATP1B3)" adult stage " adult thorax

, adult head

, adult abdomen

" " embryonic stage , adult stage , embryonic stage -- adult stage " " central nervous system

, adult abdomen

, embryonic peripheral nervous system

, pupal/adult digestive system

, embryonic/larval garland cell

, leg

, commissure

, adult head

, longitudinal connective

, adult muscle system

, adult thorax

, Malpighian tubule

, head

, embryonic/larval posterior spiracle

" viable DRSC03382 I 0.07862726 2.940846423 -0.270876617 0.293291333 -0.474226552 -0.286744536 FBgn0036299 Tsf2 Transferrin 2 http://flybase.net/reports/FBgn0036299.html protein_coding_gene "0005381=iron ion transmembrane transporter activity, 0005506=iron ion binding" 0019991=septate junction assembly "0055037=recycling endosome, 0046658=anchored component of plasma membrane, 0005886=plasma membrane, 0005769=early endosome, 0005918=septate junction, 0005829=cytosol, 0005576=extracellular region" "Melanotransferrin, MTf, tsf2, CG10620" "IPR001156=Transferrin-like domain, IPR018195=Transferrin family, iron binding site" CG10620 16-Dec-15 2015_12 "ENSDARG00000013240(zgc:172271),ENSDARG00000016771(tfa)" "ENSXETG00000011814(Q501K5_XENTR),ENSXETG00000019380(MFI2)" "ENSG00000163975(MFI2),ENSG00000012223(LTF),ENSG00000091513(TF)" "lethal,lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval dorsal trunk,septate junction | embryonic stage 16" FBgn0000416 Sap-r Saposin-related http://flybase.net/reports/FBgn0000416.html "FBgn0026286, FBgn0027566" protein_coding_gene "0006665=sphingolipid metabolic process, 0033227=dsRNA transport" "0045169=fusome, 0005764=lysosome" "anon-EST:ParkEST270, Ov9, Saposin-r, BcDNA:GH08312, Sapr, CG12070, DAPA, Sap-R, sap-r, Aggregation promoting activity, Drosophila Aggregation promoting activity, 110kD protein, P110, Apa" "IPR007856=Saposin-like type B, region 1, IPR011001=Saposin-like, IPR008138=Saposin B type, region 2, IPR008139=Saposin B type domain, IPR003119=Saposin A-type domain, IPR008373=Saposin" CG12070 16-Dec-15 2015_12 "ENSMUSG00000043430(Psapl1),ENSMUSG00000004207(Psap)" ENSG00000197746(PSAP) "viable,fertile" FBgn0050344 CG30344 http://flybase.net/reports/FBgn0050344.html FBgn0033386 protein_coding_gene 0005215=transporter activity "0031427=response to methotrexate, 0055085=transmembrane transport" 0016021=integral component of membrane "multidrug efflux transporter, CG8054, MET" "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG30344 16-Dec-15 2015_12 ENSDARG00000026149(slc46a1) YJL163C() "WBGene00021159(Y4C6B.5),WBGene00009582(F40F9.5),WBGene00012811(Y43F8A.5)" ENSXETG00000023785(SLC46A1) "ENSMUSG00000020829(Slc46a1),ENSMUSG00000029650(Slc46a3)" "ENSG00000076351(SLC46A1),ENSG00000139508(SLC46A3)" viable FBgn0030468 CG1622 http://flybase.net/reports/FBgn0030468.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome IPR005037=Pre-mRNA-splicing factor 38 CG1622 16-Dec-15 2015_12 ENSDARG00000053101(prpf38b) WBGene00022434(Y108G3AL.2) ENSXETG00000005260(prpf38b) ENSMUSG00000027881(Prpf38b) ENSG00000134186(PRPF38B) viable FBgn0086674 Tango13 Transport and Golgi organization 13 http://flybase.net/reports/FBgn0086674.html "FBgn0040865, FBgn0052632, FBgn0052629, FBgn0030497, FBgn0030498" protein_coding_gene 0008476=protein-tyrosine sulfotransferase activity "0006478=peptidyl-tyrosine sulfation, 0009306=protein secretion" 0005794=Golgi apparatus "CG32629, TANGO13, Transport and Golgi organization 13, CG15759, CG32632, CG15758, CG32629/CG32632, CG1573" "IPR026634=Protein-tyrosine sulfotransferase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG32632 16-Dec-15 2015_12 ENSDARG00000044513(tpst1l) WBGene00013737(tpst-1) ENSXETG00000017664(tpst1) "ENSMUSG00000034118(Tpst1),ENSMUSG00000029344(Tpst2)" "ENSG00000169902(TPST1),ENSG00000128294(TPST2)" "lethal,viable,partially lethal - majority die,visible,body color defective,some die during pupal stage" "trichogen cell,mesothoracic tergum" """DRSC19723, DRSC25422"" " IK FBgn0041087 wun2 wunen-2 http://flybase.net/reports/FBgn0041087.html "FBgn0025690, FBgn0026382, FBgn0033411, FBgn0040264, FBgn0062263" protein_coding_gene "0042577=lipid phosphatase activity, 0008195=phosphatidate phosphatase activity, 0005319=lipid transporter activity" "0007280=pole cell migration, 0007277=pole cell development, 0035233=germ cell repulsion, 0008354=germ cell migration, 0016311=dephosphorylation, 0007281=germ cell development, 0035234=ectopic germ cell programmed cell death" "0005886=plasma membrane, 0016021=integral component of membrane, 0045177=apical part of cell" "LPP-like, wun-2, CG8805, wunen 2, Tunen, DrPAP2[G], wunen2, CK02248, Wunen 2, BEST:CK02248, Wunen2, N14, WUN-like, Pap2G, Wun2" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG8805 16-Dec-15 2015_12 "ENSDARG00000059933(si:dkey-19f4.1),ENSDARG00000069940(zgc:158309),ENSDARG00000002231(LOC563806),ENSDARG00000028896(zgc:66434)" WBGene00018756(F53C3.13) "ENSXETG00000011144(ppap2b),ENSXETG00000000375(ppap2a),ENSXETG00000026886(ppap2c)" "ENSMUSG00000028517(Ppap2b),ENSMUSG00000021759(Ppap2a),ENSMUSG00000052151(Ppap2c)" "ENSG00000067113(PPAP2A),ENSG00000141934(PPAP2C),ENSG00000162407(PPAP2B)" "viable,neuroanatomy defective,sterile,decreased cell number,maternal effect,increased cell death,germline clone,visible,partially lethal - majority die,some die during pupal stage" "anterior fascicle & synapse,germline cell,pole cell | embryonic stage,pole cell & gonad & embryo | non-rescuable maternal effectw45-19g),pole cell,non-rescuable maternal effect,ovary & germ cell & adult | non-rescuable maternal effectw45-19g),maternal effect,germline clone,germline cell | embryonic stage 15,germline cell | embryonic stage 16,mesothoracic tergum" FBgn0035839 CG7550 http://flybase.net/reports/FBgn0035839.html protein_coding_gene "0016702=oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" 0055114=oxidation-reduction process "IPR012864=Cysteine oxygenase/2-aminoethanethiol dioxygenase, IPR014710=RmlC-like jelly roll fold, IPR011051=RmlC-like cupin domain" CG7550 16-Dec-15 2015_12 "ENSDARG00000053571(LOC100333373),ENSDARG00000042827(adoa)" ENSXETG00000014073(ADO) ENSMUSG00000057134(Ado) ENSG00000181915(ADO) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000299 Cg25C Collagen type IV http://flybase.net/reports/FBgn0000299.html protein_coding_gene 0005201=extracellular matrix structural constituent "0055013=cardiac muscle cell development, 0035848=oviduct morphogenesis, 0007391=dorsal closure" "0005581=collagen trimer, 0005604=basement membrane, 0005587=collagen type IV trimer" "Laminin alpha3,5, Collagen IV, Cgc25C, Coll, cg25C, preprocollagen alpha1(IV), Dcg, DCg1, Dcg1, col4a1, Col IV alpha(1), type IV collagen, alpha-chain, CT12803, collagen type IV, collagenIV a1, CG4145, gp125, Cgc25, cg25c, CG25C, collagen IV, collagen, type IV collagen, Coll IV, Type IV collagen, alpha1, alpha(IV)1/Cg25C" "IPR001442=Collagen IV, non-collagenous, IPR016187=C-type lectin fold, IPR008160=Collagen triple helix repeat" CG4145 16-Dec-15 2015_12 ENSDARG00000002831(col4a4) WBGene00002280(let-2) ENSXETG00000002637(COL4A1) "ENSMUSG00000031274(Col4a5),ENSMUSG00000031502(Col4a1),ENSMUSG00000079465(Col4a3),ENSMUSG00000031273(Col4a6)" "ENSG00000188153(COL4A5),ENSG00000187498(COL4A1),ENSG00000169031(COL4A3),ENSG00000134871(COL4A2)" " embryonic stage | stage 15-16 , embryonic stage | stage 16-17 , larval stage | first instar " " embryonic/larval hemocyte

, embryonic/larval fat body

" " pupal stage | stage P6 , P | stage P5 " " leg & joint | distal

, leg & joint

" "viable,fertile,lethal,recessive,dominant,cold sensitive,heat sensitive,partially lethal - majority die,female sterile,locomotor behavior defective,partially,some die during embryonic stage,neuroanatomy defective,small body,lethal - all die before end of larval stage,some die during larval stage" "common oviduct circular muscle,heat sensitive,lateral oviduct circular muscle,ovarian basement membrane,mitochondrial membrane,intracellular membrane-bounded organelle,embryonic/larval cuticle,dorsal,head,embryonic/larval central nervous system,embryonic/larval brain,embryonic/larval optic lobe,muscle attachment site,apodeme,embryonic/larval somatic muscle,somatic muscle,leg & adult apodeme,embryonic/larval visceral muscle" DRSC03291 E 0.910765943 0.311758324 1.529056422 0.264942366 -0.362263233 -0.41093042 FBgn0033526 Caf1-105 "Chromatin assembly factor 1, p105 subunit" http://flybase.net/reports/FBgn0033526.html protein_coding_gene "0042393=histone binding, 0003677=DNA binding" "0045747=positive regulation of Notch signaling pathway, 0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" 0033186=CAF-1 complex "CAF105/75, CAF1-p75/p105, p105/p75, p75, dCAF-1-p105, CAF1-p75, p105, dCAF1-p75, CAF1-105, CAF1p105, dCAF1-p105, CAF p105, CAF1-p105, caf1-105, Caf1-10, CG12892, Caf1-105, p75/p105" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site" CG12892 16-Dec-15 2015_12 ENSDARG00000056473(chaf1b) YML102W(CAC2) WBGene00022141(Y71G12B.1) ENSXETG00000013014(CHAF1B) ENSMUSG00000022945(Chaf1b) ENSG00000159259(CHAF1B) "viable,fertile,lethal - all die before end of pupal stage,developmental rate defective,small body,visible,somatic clone - Minute background" "wing,somatic clone - Minute background,trichogen cell,eye" FBgn0020620 RN-tre Related to the N terminus of tre oncogene http://flybase.net/reports/FBgn0020620.html FBgn0033892 protein_coding_gene 0005096=GTPase activator activity "0043087=regulation of GTPase activity, 0007298=border follicle cell migration" 0031982=vesicle "CG8085, DRN-tre, tre oncogene-related protein, TRE oncoprotein related, CG13351, unnamed, Tre oncoprotein related" IPR000195=Rab-GTPase-TBC domain CG8085 16-Dec-15 2015_12 "ENSDARG00000011088(LOC558401),ENSDARG00000051836(im:6904482),ENSDARG00000022187(si:ch211-198d18.2)" ENSXETG00000020613() "ENSG00000185128(TBC1D3F),ENSG00000197681(TBC1D3),ENSG00000174115,ENSG00000161583(TBC1D3G),ENSG00000215748,ENSG00000213474,ENSG00000188849,ENSG00000205019,ENSG00000189309,ENSG00000215625,ENSG00000218335,ENSG00000204471,ENSG00000188755,ENSG00000148429(USP6NL)" "neuroanatomy defective,viable,planar polarity defective,cell migration defective" "mushroom body & axon7B,Kenyon cell,adult mushroom body,mushroom body & axonc739,eye photoreceptor cell,eye,border follicle cell" FBgn0034118 Nup62 Nucleoporin 62kD http://flybase.net/reports/FBgn0034118.html FBgn0015779 protein_coding_gene "0005487=nucleocytoplasmic transporter activity, 0017056=structural constituent of nuclear pore" 0006909=phagocytosis "0044613=nuclear pore central transport channel, 0005643=nuclear pore" "p62, Nucleoporin 62, Nup62, Nucleoporin, CG6251" "IPR026010=Nucleoporin NSP1/NUP62, IPR007758=Nucleoporin, NSP1-like, C-terminal" CG6251 16-Dec-15 2015_12 ENSDARG00000020527(zgc:172056) ENSXETG00000009637(nup62) ENSMUSG00000043858(Nup62) ENSG00000213024(NUP62) "viable,cell growth defective" DRSC06970 K -0.228288196 -0.076428078 0.362271102 1.230020171 -0.422605905 1.601713684 FBgn0028697 RpL15 Ribosomal protein L15 http://flybase.net/reports/FBgn0028697.html "FBgn0002298, FBgn0058199, FBan0017420" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "l(3)80Fi, DmRpL15, CG40199, l(3)Lh2, L15, ribosomal L15, lethal 2, l2, CG17420, 80Fi, lethal (3) 80Fi, RPL15" "IPR020925=Ribosomal protein L15e, conserved site, IPR024794=Ribosomal protein L15e core domain, IPR000439=Ribosomal protein L15e, IPR012678=Ribosomal protein L23/L15e core domain" CG17420 16-Dec-15 2015_12 ENSDARG00000009285(rpl15) "YLR029C(RPL15A),YMR121C(RPL15B)" WBGene00004427(rpl-15) ENSXETG00000003870(rpl15) "ENSMUSG00000012405(Rpl15),ENSMUSG00000061167,ENSMUSG00000078377(Gm4294),ENSMUSG00000073229,ENSMUSG00000059565(Gm5292)" "ENSG00000174748(RPL15),ENSG00000215003" "lethal,sterile,visible,partially,female,recessive,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,Minute,developmental rate defective,female sterile" "gonad,macrochaeta,eye,male genitalia,wing,wing vein,wing hair,chaeta,genitalia,sex comb,ommatidium,ovary" DRSC20963 E -0.974997666 -0.103730465 0.378107734 -3.069948573 1.358483941 1.364614045 FBgn0030365 Tango4 Transport and Golgi organization 4 http://flybase.net/reports/FBgn0030365.html protein_coding_gene "0000398=mRNA splicing, via spliceosome, 0009306=protein secretion, 0007030=Golgi organization" "0005829=cytosol, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0000974=Prp19 complex" "TANGO4, CG1796" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat" CG1796 16-Dec-15 2015_12 ENSDARG00000037283(plrg1) YPL151C(PRP46) WBGene00006481(tag-135) ENSXETG00000022434(plrg1) ENSMUSG00000027998(Plrg1) ENSG00000171566(PLRG1) viable DRSC19786 IK 0.152277484 2.029809526 -0.34221659 0.913388729 -1.793669698 0.179515033 FBgn0032013 Scgë± Sarcoglycan ë± http://flybase.net/reports/FBgn0032013.html protein_coding_gene "0005509=calcium ion binding, 0008307=structural constituent of muscle" 0016012=sarcoglycan complex "Scga, DmSCG-alphaepsilon, CG7851, Scgalpha" "IPR013783=Immunoglobulin-like fold, IPR006644=Dystroglycan-type cadherin-like, IPR015919=Cadherin-like, IPR008908=Sarcoglycan alpha/epsilon" CG7851 16-Dec-15 2015_12 ENSDARG00000012138(sgce) WBGene00019227(sgca-1) ENSXETG00000003373(SGCA) "ENSMUSG00000004631(Sgce),ENSMUSG00000001508(Sgca)" "ENSG00000127990(SGCE),ENSG00000108823(SGCA)" viable FBgn0053801 His1:CG33801 His1:CG33801 http://flybase.net/reports/FBgn0053801.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33801 "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5" CG33801 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0034087 clu clueless http://flybase.net/reports/FBgn0034087.html FBgn0062217 protein_coding_gene 0003743=translation initiation factor activity "0048312=intracellular distribution of mitochondria, 0055059=asymmetric neuroblast division, 0006413=translational initiation, 0051646=mitochondrion localization" "0005852=eukaryotic translation initiation factor 3 complex, 0072686=mitotic spindle, 0005737=cytoplasm" "Clu, clu, anon-WO0118547.143, CG8443, clueless" "IPR007967=Protein of unknown function DUF727, IPR028275=Clustered mitochondria protein, N-terminal, IPR027523=Clustered mitochondria protein, IPR025697=CLU domain, IPR023231=GSKIP domain, IPR011990=Tetratricopeptide-like helical domain" CG8443 16-Dec-15 2015_12 "ENSDARG00000030913(zgc:152873),ENSDARG00000060566(LOC100150676)" YMR012W(CLU1) WBGene00000550(clu-1) ENSXETG00000019399() ENSMUSG00000020741(1300001I01Rik) ENSG00000132361(KIAA0664) "viable,developmental rate defective,short lived,flightless,locomotor behavior defective,male sterile,female sterile,lethal,recessive,small body,uncoordinated,sterile,partially lethal - majority die,male semi-sterile,fertile,body color defective" "wing,mitochondrion,flight muscle,ovary,mitochondrial inner membrane,mitochondrial crista,female germline stem cell,embryonic/larval fat body,Nebenkern derivative,female germline cell,mesothoracic tergum" DRSC07181 E 0.375854713 -0.742597867 0.311038404 1.780487504 0.022580104 -0.120986793 FBgn0033644 Tret1-2 Trehalose transporter 1-2 http://flybase.net/reports/FBgn0033644.html protein_coding_gene "0005355=glucose transmembrane transporter activity, 0005353=fructose transmembrane transporter activity" "0015771=trehalose transport, 0055085=transmembrane transport" "0016021=integral component of membrane, 0016020=membrane" "CG8234, DmTret1-2" "IPR005828=Major facilitator, sugar transporter-like, IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR003663=Sugar/inositol transporter" CG8234 16-Dec-15 2015_12 YDR387C() "WBGene00010811(hmit-1.3),WBGene00013073(hmit-1.1),WBGene00013074(hmit-1.2)" "ENSXETG00000019602(SLC2A8),ENSXETG00000006884(SLC2A6)" "ENSMUSG00000026791(Slc2a8),ENSMUSG00000036067(Slc2a6)" "ENSG00000136856(SLC2A8),ENSG00000160326(SLC2A6)" viable FBgn0050100 CG30100 http://flybase.net/reports/FBgn0050100.html protein_coding_gene 0003747=translation release factor activity 0006415=translational termination Dromel_CG30100_FBtr0087140_mORF "IPR000352=Peptide chain release factor class I/class II, IPR014720=Double-stranded RNA-binding domain" CG30100 16-Dec-15 2015_12 ENSDARG00000059447(LOC100004452) YLR281C() WBGene00011941(T23B5.4) ENSMUSG00000047635(2810006K23Rik) ENSG00000130921(C12orf65) "viable,fertile" FBgn0250791 ë±Snap ë± Soluble NSF attachment protein http://flybase.net/reports/FBgn0250791.html "FBgn0011712, FBgn0029028, FBgn0029029" protein_coding_gene "0000149=SNARE binding, 0005483=soluble NSF attachment protein activity, 0001671=ATPase activator activity" "0006888=ER to Golgi vesicle-mediated transport, 0007268=synaptic transmission, 0016082=synaptic vesicle priming, 0006886=intracellular protein transport, 0031629=synaptic vesicle fusion to presynaptic membrane, 0007269=neurotransmitter secretion, 0051260=protein homooligomerization, 0007274=neuromuscular synaptic transmission, 0000281=mitotic cytokinesis, 0006909=phagocytosis, 0048812=neuron projection morphogenesis, 0001745=compound eye morphogenesis, 0006891=intra-Golgi vesicle-mediated transport, 0048526=imaginal disc-derived wing expansion, 0035494=SNARE complex disassembly, 0034214=protein hexamerization" "0005737=cytoplasm, 0031410=cytoplasmic vesicle, 0019898=extrinsic component of membrane, 0043195=terminal bouton, 0016020=membrane, 0043679=axon terminus, 0031201=SNARE complex" "Snap, l(3)77ABa, dalphaSNAP, CG6625, soluble N-ethylmaleimide-sensitive factor attachment protein, dalpha-SNAP, snap, SNAP, aSnap, soluble NSF attachment protein, alphaSnap, Soluble NSF attachment protein, dSNAP, lethal (3) 77ABc, lethal (3) 77ABa, dsnap, alpha-SNAP, soluble NSF-attachment protein, l(3)77ABc" "IPR000744=NSF attachment protein, IPR011990=Tetratricopeptide-like helical domain" CG6625 16-Dec-15 2015_12 "ENSDARG00000020405(napa),ENSDARG00000021276,ENSDARG00000067605(si:dkeyp-117b8.3),ENSDARG00000013669(LOC100333512)" YBL050W(SEC17) WBGene00017016(snap-1) ENSXETG00000002788(napa) "ENSMUSG00000006024(Napa),ENSMUSG00000027438(Napb)" "ENSG00000105402(NAPA),ENSG00000125814(NAPB)" " larval stage , embryonic stage | late , adult stage " embryonic central nervous system

DRSC11285 IEK -1.184151058 1.610543437 -0.827370986 -3.334247002 -2.858081866 -1.993764221 FBgn0044048 Ilp5 Insulin-like peptide 5 http://flybase.net/reports/FBgn0044048.html FBgn0053273 protein_coding_gene "0005179=hormone activity, 0005158=insulin receptor binding" "0060180=female mating behavior, 0008286=insulin receptor signaling pathway, 0007623=circadian rhythm, 0030431=sleep, 0007626=locomotory behavior" 0005615=extracellular space "insulin like peptide 5, CG33273, dilp-5, Dilp5, Dilp 5, dilp5, dilp, Ilp-5, Ilp, dIlp5, Dilp, Dilp-5, DILP-5, DILP5, Drosophila insulin-like peptide 5, dILP5, ilp5, insulin-like peptide 5, insulin-like peptide, insulin-like peptide-5, DILP, ILP5, dILP-5" "IPR016179=Insulin-like, IPR022352=Insulin family, IPR022353=Insulin, conserved site" CG33273 16-Dec-15 2015_12 "ENSDARG00000034610(insb),ENSDARG00000035350(LOC100334156)" " larval stage | third instar , larval stage | third instar stage 2 " " embryonic/larval midgut

, larval brain | restricted

anterior & medial , larval brain | restricted

" "large body,chemical resistant,long lived,viable,mating defective,sleep defective" embryonic/larval neuroblast FBgn0051522 CG31522 http://flybase.net/reports/FBgn0051522.html "FBan0031522, FBgn0037253, FBgn0047218, FBgn0062052, FBgn0064960" protein_coding_gene 0009922=fatty acid elongase activity "0006633=fatty acid biosynthetic process, 0030497=fatty acid elongation, 0000038=very long-chain fatty acid metabolic process" 0016021=integral component of membrane "anon-WO0118547.381, BcDNA:GH22993, BcDNA:LD10305, CG9798" IPR002076=ELO family CG31522 16-Dec-15 2015_12 "ENSDARG00000005785(elovl7b),ENSDARG00000069279(elovl7a),ENSDARG00000058356(elovl1b),ENSDARG00000002412(elovl1a)" "YJL196C(ELO1),YCR034W(FEN1),YLR372W(SUR4)" "ENSXETG00000009581(ELOVL1),ENSXETG00000016688(elovl7)" "ENSMUSG00000021696(Elovl7),ENSMUSG00000006390(Elovl1)" "ENSG00000164181(ELOVL7),ENSG00000066322(ELOVL1)" viable FBgn0034172 CG6665 http://flybase.net/reports/FBgn0034172.html protein_coding_gene IPR010876=NICE-3 predicted CG6665 16-Dec-15 2015_12 ENSDARG00000055613(zgc:123238) ENSXETG00000020733(C1orf43) ENSMUSG00000027942(4933434E20Rik) ENSG00000143612(C1orf43) viable FBgn0262732 mbf1 multiprotein bridging factor 1 http://flybase.net/reports/FBgn0262732.html "FBgn0026208, FBgn0027555, FBgn0063210, FBgn0086536" protein_coding_gene "0030674=protein binding, bridging, 0008327=methyl-CpG binding, 0003713=transcription coactivator activity" "0007417=central nervous system development, 0048813=dendrite morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007424=open tracheal system development" "0005737=cytoplasm, 0005634=nucleus" "MBF-1, BcDNA:GH10148, MBF1, MRE4, mRNA-like ncRNA in embryogenesis 4, CG4143, Mbf-1, BcDNA:GM01267, Mbf1, Multiprotein bridging factor 1" "IPR013729=Multiprotein bridging factor 1, N-terminal, IPR001387=Cro/C1-type helix-turn-helix domain, IPR010982=Lambda repressor-like, DNA-binding domain" CG4143 16-Dec-15 2015_12 ENSDARG00000009950(edf1) YOR298C-A(MBF1) WBGene00003148(mbf-1) ENSXETG00000003971(edf1) ENSMUSG00000015092(Edf1) ENSG00000107223(EDF1) FBgn0020249 stck steamer duck http://flybase.net/reports/FBgn0020249.html FBgn0026191 protein_coding_gene 0008270=zinc ion binding "0008258=head involution, 0007391=dorsal closure, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0009880=embryonic pattern specification, 0046329=negative regulation of JNK cascade" "0031252=cell leading edge, 0005925=focal adhesion" "steamerduck, d-pinch, D-PINCH, pinch, CG7954, PINCH, dPINCH, Steamer duck, dpin, pin85A, stk, Pinch" "IPR001781=Zinc finger, LIM-type, IPR017351=LIM and senescent cell antigen-like-containing domain protein 1" CG7954 16-Dec-15 2015_12 ENSDARG00000026985(lims1) WBGene00006826(unc-97) ENSXETG00000015993() "ENSMUSG00000024395(Lims2),ENSMUSG00000019920(Lims1)" "ENSG00000169756(LIMS1),ENSG00000072163(LIMS2)" " embryonic stage | stage 16 , embryonic stage | stage 13 , embryonic stage | stage 10 " " visceral mesoderm

, muscle attachment site

, mesoderm

" "visible,viable,lethal,recessive,hypoactive,somatic clone,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone,embryonic/larval somatic muscle,larva,embryonic somatic muscle,myofibril & actin filament097),embryonic/first instar larval cuticle,dorsal,germline clone,embryonic head" FBgn0053180 Ranbp16 Ranbp16 http://flybase.net/reports/FBgn0053180.html "FBgn0030708, FBgn0030709" protein_coding_gene "0008536=Ran GTPase binding, 0005049=nuclear export signal receptor activity" 0006611=protein export from nucleus "0005634=nucleus, 0005737=cytoplasm, 0005643=nuclear pore" "CG9126, RanBP16, CG9136, CG33180" "IPR016024=Armadillo-type fold, IPR001494=Importin-beta, N-terminal domain" CG33180 16-Dec-15 2015_12 ENSDARG00000005540(xpo7) WBGene00007952(C35A5.8) ENSXETG00000010544(XPO7) "ENSMUSG00000022100(Xpo7),ENSMUSG00000040594(Ranbp17)" "ENSG00000130227(XPO7),ENSG00000204764(RANBP17)" FBgn0033038 CG7791 http://flybase.net/reports/FBgn0033038.html protein_coding_gene 0004222=metalloendopeptidase activity 0016485=protein processing 0005739=mitochondrion "IPR001567=Peptidase M3A/M3B, IPR024077=Neurolysin/Thimet oligopeptidase, domain 2, IPR024079=Metallopeptidase, catalytic domain" CG7791 16-Dec-15 2015_12 "ENSDARG00000055344(LOC100005953),ENSDARG00000055339" YKL134C(OCT1) WBGene00013464(Y67H2A.7) ENSXETG00000009705(MIPEP) ENSMUSG00000021993(Mipep) ENSG00000027001(MIPEP) "viable,visible" trichogen cell FBgn0262081 Csk C-terminal Src kinase http://flybase.net/reports/FBgn0262081.html "FBgn0086903, FBgn0086688, FBgn0024519, FBgn0037925, FBgn0023017, FBgn0052852, FBgn0259217, FBgn0041155" protein_coding_gene "0004672=protein kinase activity, 0004713=protein tyrosine kinase activity, 0005524=ATP binding" "0043068=positive regulation of programmed cell death, 0010669=epithelial structure maintenance, 0034334=adherens junction maintenance, 0006468=protein phosphorylation, 0007165=signal transduction, 0018108=peptidyl-tyrosine phosphorylation, 0007293=germarium-derived egg chamber formation, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0045926=negative regulation of growth, 0008285=negative regulation of cell proliferation, 0016477=cell migration" 0005911=cell-cell junction "flik, lethal (3) S017909, dcsk, dCSK, unnamed, C-terminal-Src kinase, C-Src kinase, CG32852, CG42317, csk, lethal (3) j1D8, l(3)j1D8, d-Csk, l(3)S017909, CSK, DCsk, CG17309, Drosophila C-terminal Src kinase, dCsk" "IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR017441=Protein kinase, ATP binding site, IPR000980=SH2 domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG42317 16-Dec-15 2015_12 "WBGene00008487(F01D4.3),WBGene00020289(T06C10.3),WBGene00021151(Y4C6A.1),WBGene00020992(W03F8.2),WBGene00020003(R11E3.1),WBGene00012172(W01B6.5),WBGene00019081(F59A3.8),WBGene00012010(T25B9.4),WBGene00017736(F23C8.7),WBGene00016085(C25A8.5),WBGene00002208(kin-26),WBGene00002193(kin-5),WBGene00016954(C55C3.4),WBGene00016462(C35E7.10),WBGene00018999(F57B9.8),WBGene00022780(ZK622.1),WBGene00001487(frk-1),WBGene00002212(kin-31),WBGene00014005(ZK593.9)" pupal stage salivary gland

DRSC23272 K -0.769165116 -0.503492429 -0.177355526 -0.584595293 -0.492363755 1.755578359 FBgn0030789 Rrp45 Rrp45 http://flybase.net/reports/FBgn0030789.html protein_coding_gene 0000175=3'-5'-exoribonuclease activity 0006397=mRNA processing "0000176=nuclear exosome (RNase complex), 0000177=cytoplasmic exosome (RNase complex), 0000178=exosome (RNase complex)" "CG9606, rrp45, dRrp45" "IPR001247=Exoribonuclease, phosphorolytic domain 1, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR027408=PNPase/RNase PH domain, IPR015847=Exoribonuclease, phosphorolytic domain 2" CG9606 16-Dec-15 2015_12 ENSDARG00000006392(exosc9) YDR280W(RRP45) WBGene00018154(exos-9) ENSXETG00000021118(EXOSC9) ENSMUSG00000027714(Exosc9) ENSG00000123737(EXOSC9) "lethal,recessive,viable" FBgn0033792 CG13325 http://flybase.net/reports/FBgn0033792.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG13325 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" "viable,fertile" FBgn0036603 CG13062 http://flybase.net/reports/FBgn0036603.html protein_coding_gene IPR007614=Retinin-like protein CG13062 16-Dec-15 2015_12 viable FBgn0083941 CG34105 http://flybase.net/reports/FBgn0083941.html protein_coding_gene CG34105 16-Dec-15 2015_12 FBgn0038976 CG7048 http://flybase.net/reports/FBgn0038976.html protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding 0016272=prefoldin complex "IPR011599=Prefoldin alpha subunit, archaea-type, IPR009053=Prefoldin, IPR004127=Prefoldin alpha-like" CG7048 16-Dec-15 2015_12 ENSDARG00000035043(pfdn5) YML094W(GIM5) WBGene00020112(pfd-5) ENSXETG00000012667(pfdn5) ENSMUSG00000001289(Pfdn5) ENSG00000123349(PFDN5) "lethal,viable,visible" "embryonic/larval brain,trichogen cell" FBgn0014033 Sr-CI "Scavenger receptor class C, type I" http://flybase.net/reports/FBgn0014033.html protein_coding_gene "0005044=scavenger receptor activity, 0030247=polysaccharide binding" "0009617=response to bacterium, 0006952=defense response, 0006955=immune response, 0006909=phagocytosis, 0050829=defense response to Gram-negative bacterium" "0005887=integral component of plasma membrane, 0016020=membrane" "Sr-Cl, SR-CI, scavenger receptor class C, type 1, dScR-I, Scavenger receptor C, type I, SR-C1, Scavenger Receptor, CT9876, dSR-C1, dSR-CI, D-SR-CI, CG4099, DSR-CI, Sr-C1, dSRC-I" "IPR000998=MAM domain, IPR000436=Sushi/SCR/CCP domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001212=Somatomedin B domain" CG4099 16-Dec-15 2015_12 "ENSXETG00000020534(MEP1B),ENSXETG00000016251(Q5FVY5_XENTR)" "ENSMUSG00000026399(Cd55),ENSMUSG00000026401(Daf2)" embryonic stage " embryonic/larval hemocyte

, macrophage

" viable DRSC23942 K -0.698943034 -0.415570321 0.685909403 -0.281510956 1.732215836 -0.032793406 FBgn0036004 Jarid2 "Jumonji, AT rich interactive domain 2" http://flybase.net/reports/FBgn0036004.html protein_coding_gene 0003677=DNA binding 0061085=regulation of histone H3-K27 methylation "0035098=ESC/E(Z) complex, 0005719=nuclear euchromatin, 0005700=polytene chromosome, 0005634=nucleus" "jumonji, dJARID2, CG3654, djmj, JARID2, dJmj" "IPR004198=Zinc finger, C5HC2-type, IPR003347=JmjC domain, IPR001606=ARID DNA-binding domain, IPR017956=AT hook, DNA-binding motif, IPR003349=JmjN domain" CG3654 16-Dec-15 2015_12 "ENSDARG00000062268(jarid2b),ENSDARG00000060925(jarid2a)" ENSG00000008083(JARID2) "viable,suppressor of variegation,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,fertile,visible,dominant" "polytene chromosome,leg,embryonic/larval hemocyte | third instar larval stage,wing vein,ectopic" FBgn0030366 Usp7 Ubiquitin-specific protease 7 http://flybase.net/reports/FBgn0030366.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0016579=protein deubiquitination, 0006511=ubiquitin-dependent protein catabolic process, 0006342=chromatin silencing, 0016578=histone deubiquitination" "0043234=protein complex, 0005634=nucleus, 0005700=polytene chromosome, 0035328=transcriptionally silent chromatin" "ubiquitin-specific protease 7, CG1490, USP7, Usp-7, Q9VYQ8" "IPR002083=MATH/TRAF domain, IPR018200=Ubiquitin specific protease, conserved site, IPR029346=Ubiquitin carboxyl-terminal hydrolase, C-terminal, IPR028889=Ubiquitin specific protease domain, IPR008974=TRAF-like, IPR024729=Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain, IPR001394=Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG1490 16-Dec-15 2015_12 ENSDARG00000041978 YMR304W(UBP15) WBGene00010406(math-33) ENSXETG00000008697(USP7) ENSMUSG00000022710(Usp7) ENSG00000187555(USP7) "short lived,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,sterile,lethal,male,body color defective,partially lethal - majority die,visible" "wing,mesothoracic tergum,scutellar bristle" FBgn0036136 Ufd1-like Ubiquitin fusion-degradation 1-like http://flybase.net/reports/FBgn0036136.html FBgn0062035 protein_coding_gene "0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0098586=cellular response to virus, 0006511=ubiquitin-dependent protein catabolic process, 0006508=proteolysis" 0000502=proteasome complex "dUfd1, CG6233, ufd1-like, UfD1-like, UFD1, anon-WO0118547.405, dUFD1L, Ufd1 like, Ubiquitin fusion-degradation, Ufd1L, ufd1, Ufd1, Ufd-1, Udf1" IPR004854=Ubiquitin fusion degradation protein UFD1 CG6233 16-Dec-15 2015_12 ENSDARG00000010051(ufd1l) YGR048W(UFD1) WBGene00006733(ufd-1) ENSXETG00000018601(Q6DFQ4_XENTR) ENSMUSG00000005262(Ufd1l) ENSG00000070010(UFD1L) "viable,stress response defective" DRSC10607 K -0.616787643 0.046258163 -0.651692926 0.514236777 1.92313747 0.811263903 FBgn0034710 CG3292 http://flybase.net/reports/FBgn0034710.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR017850=Alkaline-phosphatase-like, core domain, IPR018299=Alkaline phosphatase, active site, IPR001952=Alkaline phosphatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG3292 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0028658 Adat1 "Adenosine deaminase, tRNA-specific 1" http://flybase.net/reports/FBgn0028658.html protein_coding_gene "0008251=tRNA-specific adenosine deaminase activity, 0003723=RNA binding" 0006400=tRNA modification "CG16889, dADAT1, adat, BG:DS00941.2, Adat" IPR002466=Adenosine deaminase/editase CG16889 16-Dec-15 2015_12 ENSDARG00000061348(adat1) YGL243W(TAD1) ENSXETG00000003571(adat1) " embryonic stage | stage 8-12 , embryonic stage | stage >12 , embryonic stage | early " " ventral neurogenic region

, embryonic central nervous system

, mesoderm

, embryonic brain

, ventral nerve cord

" "partially lethal - majority die,some die during pupal stage" FBgn0065724 l(2)SH0563 lethal (2) SH0563 http://flybase.net/reports/FBgn0065724.html gene l(2)SH2 0563 16-Dec-15 2015_12 "lethal,recessive" FBgn0036287 CG10663 http://flybase.net/reports/FBgn0036287.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP30, CT29868" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR001254=Serine proteases, trypsin domain" CG10663 16-Dec-15 2015_12 "ENSXETG00000004084(),ENSXETG00000017056(),ENSXETG00000000325(OVCH1),ENSXETG00000023763(TEgg131d18.1)" "ENSG00000154646(TMPRSS15),ENSG00000184012(TMPRSS2),ENSG00000160183(TMPRSS3)" "viable,fertile" FBgn0027601 pdgy pudgy http://flybase.net/reports/FBgn0027601.html protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity "0071616=acyl-CoA biosynthetic process, 0019433=triglyceride catabolic process, 0009062=fatty acid catabolic process, 0046627=negative regulation of insulin receptor signaling pathway" "BcDNA:GH02901, long chain fatty acid CoA ligase, CG9009" "IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site, IPR025110=AMP-binding enzyme C-terminal domain" CG9009 16-Dec-15 2015_12 YBR222C(PCS60) ENSXETG00000019194() "viable,fertile,long lived,nutrition conditional,small body" FBgn0051812 CG31812 http://flybase.net/reports/FBgn0051812.html protein_coding_gene "0003676=nucleic acid binding, 0000213=tRNA-intron endonuclease activity" "0006388=tRNA splicing, via endonucleolytic cleavage and ligation" 0000214=tRNA-intron endonuclease complex "IPR006676=tRNA-splicing endonuclease, IPR006678=tRNA intron endonuclease, N-terminal, IPR006677=tRNA intron endonuclease, catalytic domain-like, IPR011856=tRNA endonuclease-like domain" CG31812 16-Dec-15 2015_12 ENSDARG00000070920 YLR105C(SEN2) ENSMUSG00000042389(Tsen2) ENSG00000154743(TSEN2) "viable,visible" trichogen cell FBgn0005593 RpL7 Ribosomal protein L7 http://flybase.net/reports/FBgn0005593.html FBgn0043838 protein_coding_gene "0019843=rRNA binding, 0003729=mRNA binding, 0003735=structural constituent of ribosome" "0007052=mitotic spindle organization, 0035073=pupariation, 0000022=mitotic spindle elongation, 0006412=translation, 0051298=centrosome duplication" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "BEST:GH04411, CG4897, rpl7, Rp L7, unnamed, L7, rpL7, ribosomal protein L7, RPL7" "IPR018038=Ribosomal protein L30, conserved site, IPR005998=Ribosomal protein L7, eukaryotic, IPR016082=Ribosomal protein L30, ferredoxin-like fold domain, IPR012988=Ribosomal protein L30, N-terminal" CG4897 16-Dec-15 2015_12 ENSDARG00000007320(rpl7) "YGL076C(RPL7A),YPL198W(RPL7B)" WBGene00004418(rpl-7) ENSXETG00000025457(rpl7) "ENSMUSG00000043716(Rpl7),ENSMUSG00000025922,ENSMUSG00000054284" "ENSG00000214485,ENSG00000137970,ENSG00000147604(RPL7)" "lethal,developmental rate defective" DRSC03417 IEK -3.196714529 -2.030824173 -0.053688902 -4.084685646 2.044770262 4.32480862 FBgn0021767 org-1 optomotor-blind-related-gene-1 http://flybase.net/reports/FBgn0021767.html FBgn0024203 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007525=somatic muscle development" 0005634=nucleus "CG11202, Org-1, Dm-ORG-1, optomotor-blind-related-protein-1, omb-related gene-1, optomotor-blind-related gene-1, Optomotor-blind-related-gene 1, Optomotor-blind-related-1" "IPR001699=Transcription factor, T-box, IPR008967=p53-like transcription factor, DNA-binding, IPR018186=Transcription factor, T-box, conserved site" CG11202 16-Dec-15 2015_12 "WBGene00006557(tbx-38),WBGene00006556(tbx-37)" ENSXETG00000006304(tbx1) "ENSMUSG00000009097(Tbx1),ENSMUSG00000037477(Tbx10)" "ENSG00000184058(TBX1),ENSG00000167800(TBX10)" "lethal,visible,partially lethal - majority die,some die during pupal stage" "A1-7 lateral oblique muscle 1,A1-7 segment border muscle,A2-7 ventral transverse muscle 1,embryonic/larval alary muscle,abdominal lateral adult muscle precursor cell,embryonic/larval somatic muscle,eye,antenna,third segment of antenna,macrochaeta,ectopic,arista,unguis,interommatidial bristle,tarsal segment,ommatidium,supernumerary,trichogen cell,tormogen cell" FBgn0058160 CG40160 http://flybase.net/reports/FBgn0058160.html "FBgn0047211, FBan0040160" protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region BcDNA:LD13269 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG40160 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" FBgn0000454 Dip-B Dipeptidase B http://flybase.net/reports/FBgn0000454.html FBgn0038184 protein_coding_gene "0008235=metalloexopeptidase activity, 0004177=aminopeptidase activity, 0008239=dipeptidyl-peptidase activity, 0008240=tripeptidyl-peptidase activity, 0030145=manganese ion binding" 0006508=proteolysis 0005737=cytoplasm "CG9285, DipB" "IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal" CG9285 16-Dec-15 2015_12 WBGene00012338(W07G4.4) "viable,fertile,electrophoretic variant" FBgn0263855 BubR1 Bub1-related kinase http://flybase.net/reports/FBgn0263855.html "FBgn0025458, FBgn0022226, FBgn0069180" protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0070193=synaptonemal complex organization, 0007052=mitotic spindle organization, 0007140=male meiosis, 0090307=mitotic spindle assembly, 0022008=neurogenesis, 0007096=regulation of exit from mitosis, 0007066=female meiosis sister chromatid cohesion, 0051754=meiotic sister chromatid cohesion, centromeric, 0031937=positive regulation of chromatin silencing, 0006468=protein phosphorylation, 0007065=male meiosis sister chromatid cohesion, 0010965=regulation of mitotic sister chromatid separation, 0007094=mitotic spindle assembly checkpoint" "0005737=cytoplasm, 0000940=condensed chromosome outer kinetochore, 0000776=kinetochore" "Dmbub1, bubr1, l(2)k06109, mcl(2)Z1525, BUB1, Bub1, BUBR1, CG7838, dBUB1, bubR1, bub1, CG 7838, 31/13, l(2)k03113, DmBUB1, BcDNA:LD23835, bub related one" "IPR013212=Mad3/Bub1 homology region 1, IPR015661=Mitotic spindle checkpoint protein Bub1/Mad3, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG7838 16-Dec-15 2015_12 ENSDARG00000041361(ttk) YGR188C(BUB1) WBGene00000275(bub-1) ENSXETG00000022448(BUB1) ENSMUSG00000027379(Bub1) ENSG00000169679(BUB1) FBgn0020378 Sp1 Sp1 http://flybase.net/reports/FBgn0020378.html protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0007480=imaginal disc-derived leg morphogenesis, 0000398=mRNA splicing, via spliceosome" 0005634=nucleus "D.Sp1, SP1, D-Sp1, D-Sp8, CG1343, sp1, dSp1" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR005011=SNU66/SART1 family, IPR011989=Armadillo-like helical, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG1343 16-Dec-15 2015_12 "ENSDARG00000056666(LOC100334880),ENSDARG00000011870(sp8a),ENSDARG00000010462(sp9)" WBGene00013970(ZK337.2) ENSXETG00000007432(SP8) "ENSMUSG00000068859(Sp9),ENSMUSG00000048562(Sp8)" "ENSG00000164651(SP8),ENSG00000217236(SP9)" " larval stage , larval stage | third instar , embryonic stage , oogenesis stage , embryonic stage | stage 13 , adult stage && oogenesis stage " " ventral thoracic disc

, eye-antennal disc | restricted

, ventral nerve cord | restricted

, embryonic peripheral nervous system

, larval brain | restricted

, nurse cell

, antennal disc

, oocyte

, proneural cluster

, chordotonal organ | lateral

, chordotonal organ precursor cell

, chordotonal organ precursor cell | lateral

" "homeotic,size defective,visible,viable" "wing,leg,ectopic,medial,distal,first segment of antenna,second segment of antenna,wing margin bristle" FBgn0040096 lectin-33A lectin-33A http://flybase.net/reports/FBgn0040096.html FBgn0032328 protein_coding_gene "0030246=carbohydrate binding, 0005534=galactose binding" "CG16834, lecti-33A, AC007083a, lectin-33a, AC 007083A" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG16834 16-Dec-15 2015_12 "ENSDARG00000034322,ENSDARG00000015081(si:ch211-125e6.12),ENSDARG00000027302,ENSDARG00000041241,ENSDARG00000041246,ENSDARG00000041248(si:dkey-241l7.6),ENSDARG00000025783(si:ch211-125e6.11),ENSDARG00000038321(zgc:172053),ENSDARG00000045800,ENSDARG00000037978,ENSDARG00000067820" ENSXETG00000012998() "ENSMUSG00000059639(Clec4a4),ENSMUSG00000031495(Cd209d),ENSMUSG00000030148(Clec4a2),ENSMUSG00000043832(Clec4a3),ENSMUSG00000067767(Clec4b2),ENSMUSG00000049037(Clec4a1),ENSMUSG00000030147(Clec4b1),ENSMUSG00000023349(Clec4n),ENSMUSG00000030144(Clec4d)" "ENSG00000111729(CLEC4A),ENSG00000198178(CLEC4C)" viable FBgn0039050 CG17110 http://flybase.net/reports/FBgn0039050.html protein_coding_gene 0004046=aminoacylase activity 0006520=cellular amino acid metabolic process 0005737=cytoplasm "IPR002933=Peptidase M20, IPR011650=Peptidase M20, dimerisation domain, IPR010159=N-acyl-L-amino-acid amidohydrolase" CG17110 16-Dec-15 2015_12 "ENSDARG00000004845(LOC100001620),ENSDARG00000038475(zgc:55605)" "WBGene00007507(C10C5.3),WBGene00007508(C10C5.4),WBGene00007509(C10C5.5),WBGene00015509(C06A6.4)" ENSXETG00000000089(acy1) ENSMUSG00000023262(Acy1) ENSG00000114786(ACY1) FBgn0040502 CG8343 http://flybase.net/reports/FBgn0040502.html FBgn0033066 protein_coding_gene "0030246=carbohydrate binding, 0005537=mannose binding" "GH10831, Incilarin-like, BEST:GH10831, GH10831-Inc" "IPR018378=C-type lectin, conserved site, IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG8343 16-Dec-15 2015_12 "ENSDARG00000034322,ENSDARG00000015081(si:ch211-125e6.12),ENSDARG00000027302,ENSDARG00000041241,ENSDARG00000041246,ENSDARG00000041248(si:dkey-241l7.6),ENSDARG00000025783(si:ch211-125e6.11),ENSDARG00000038321(zgc:172053),ENSDARG00000045800,ENSDARG00000037978,ENSDARG00000067820" "WBGene00012621(Y38H6C.8),WBGene00016912(clec-86),WBGene00020191(clec-53),WBGene00015052(clec-52)" "ENSMUSG00000027876(Reg4),ENSMUSG00000079516(Reg3a),ENSMUSG00000030017(Reg3g),ENSMUSG00000059654(Reg1),ENSMUSG00000071356(Reg3b),ENSMUSG00000023140(Reg2),ENSMUSG00000068341(Reg3d)" "ENSG00000134193(REG4),ENSG00000172023(REG1B),ENSG00000115386(REG1A),ENSG00000172016(REG3A),ENSG00000143954(REG3G),ENSG00000188477" viable FBgn0004003 wbl windbeutel http://flybase.net/reports/FBgn0004003.html protein_coding_gene "0042803=protein homodimerization activity, 0005515=protein binding" "0040014=regulation of multicellular organism growth, 0008063=Toll signaling pathway, 0009950=dorsal/ventral axis specification, 0000042=protein targeting to Golgi, 0016485=protein processing, 0009792=embryo development ending in birth or egg hatching, 0007313=maternal specification of dorsal/ventral axis, oocyte, soma encoded, 0009306=protein secretion" "0005783=endoplasmic reticulum, 0012505=endomembrane system, 0005788=endoplasmic reticulum lumen" "CG7225, wbt, Windbeutel, Windb, wind, Wbl, Wind" "IPR012883=ERp29, N-terminal, IPR012336=Thioredoxin-like fold, IPR016855=Endoplasmic reticulum, protein ERp29, IPR011679=Endoplasmic reticulum, protein ERp29, C-terminal" CG7225 16-Dec-15 2015_12 ENSXETG00000004300(ERP29) ENSMUSG00000029616(Erp29) ENSG00000089248(ERP29) " adult stage | male , embryonic stage | early , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S8-10 " " ovary

, follicle cell

" "wild-type,lethal,non-rescuable maternal effect,recessive,partially,small body,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,visible" "embryo,embryonic/first instar larval cuticle,maternal effect,embryonic epidermis,ventral,somatic clone,trichogen cell" FBgn0053807 His1:CG33807 His1:CG33807 http://flybase.net/reports/FBgn0053807.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0005634=nucleus, 0000786=nucleosome" CG33807 "IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15" CG33807 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0038755 Hs6st Heparan sulfate 6-O-sulfotransferase http://flybase.net/reports/FBgn0038755.html "FBgn0038754, FBgn0038759, FBgn0042209" protein_coding_gene "0017095=heparan sulfate 6-O-sulfotransferase activity, 0008146=sulfotransferase activity" "0060828=regulation of canonical Wnt signaling pathway, 0007424=open tracheal system development, 0015012=heparan sulfate proteoglycan biosynthetic process, 0007428=primary branching, open tracheal system, 0022416=chaeta development, 0045570=regulation of imaginal disc growth, 0090097=regulation of decapentaplegic signaling pathway, 0008587=imaginal disc-derived wing margin morphogenesis, 0008543=fibroblast growth factor receptor signaling pathway" 0016021=integral component of membrane "dHS6ST, hs6st, 6-O sulfotransferase, CG11683, 6-O-sulfotransferase, CG18533, CG4451, DmHs6st, CG17188, heparan sulfate 6-O-sulfotransferase" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005331=Sulfotransferase, IPR010635=Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase" CG4451 16-Dec-15 2015_12 "ENSDARG00000069500(hs6st3),ENSDARG00000071217,ENSDARG00000054754(hs6st1a),ENSDARG00000071501(hs6st1b),ENSDARG00000012025(hs6st2)" WBGene00002031(hst-6) "ENSXETG00000016769(HS6ST1),ENSXETG00000004076(HS6ST3),ENSXETG00000005408(HS6ST2)" "ENSMUSG00000045216(Hs6st1),ENSMUSG00000053465(Hs6st3),ENSMUSG00000062184(Hs6st2)" "ENSG00000136720(HS6ST1),ENSG00000185352(HS6ST3),ENSG00000171004(HS6ST2)" "viable,fertile,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,increased mortality during development,partially lethal - majority die,size defective" "eye,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval trachea,imaginal tracheoblast,presumptive embryonic/larval tracheal system,wing margin,wing disc,wing margin bristle" DRSC15581 I -2.899816299 0.237184502 0.369657153 -0.169190384 -0.051526583 -0.931438798 FBgn0001087 g garnet http://flybase.net/reports/FBgn0001087.html "FBgn0001800, FBgn0030516, FBgn0030517" protein_coding_gene 0008565=protein transporter activity "0006887=exocytosis, 0006726=eye pigment biosynthetic process, 0006895=Golgi to endosome transport, 0048072=compound eye pigmentation, 0006897=endocytosis, 0008057=eye pigment granule organization, 0060967=negative regulation of gene silencing by RNA, 0006886=intracellular protein transport, 0006727=ommochrome biosynthetic process, 0007220=Notch receptor processing, 0046907=intracellular transport, 0007041=lysosomal transport, 0007040=lysosome organization, 0008055=ocellus pigment biosynthetic process, 0008340=determination of adult lifespan" "0030123=AP-3 adaptor complex, 0005770=late endosome, 0005783=endoplasmic reticulum, 0005798=Golgi-associated vesicle, 0030131=clathrin adaptor complex, 0005795=Golgi stack" "lethal(1)Mc19, apl5, cg11197, l(1)Mc19, AP-3delta, delta, CG11197, salmon, AP3delta, Garnet, AP-3, delta subunit, CG10986, Adaptor Protein complex 3, delta subunit" "IPR010474=Bovine leukaemia virus receptor, IPR017105=Adaptor protein complex AP-3, delta subunit, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG10986 16-Dec-15 2015_12 "ENSDARG00000071424(LOC100329600),ENSDARG00000003334(si:ch211-129c21.6)" YPL195W(APL5) WBGene00000162(apd-3) ENSXETG00000013663(ap3d1) ENSMUSG00000020198(Ap3d1) ENSG00000065000(AP3D1) adult stage "eye color defective,recessive,courtship behavior defective,male,short lived,behavior defective,visible,body color defective,viable,reduced,fertile,wild-type,cell autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage,female,lethal,female fertile,male sterile" "pigment cell,testis sheath,Malpighian tubule,pigment granule,eye" DRSC20335 E 0.076386202 -0.437177995 2.861276213 0.824893468 -0.880786372 0.061513672 FBgn0036499 CG7276 http://flybase.net/reports/FBgn0036499.html protein_coding_gene "0042623=ATPase activity, coupled" 0007018=microtubule-based movement 0030286=dynein complex IPR005334=Tctex-1 CG7276 16-Dec-15 2015_12 ENSDARG00000054255(si:ch211-276k2.4) WBGene00017014(dylt-2) "ENSXETG00000006790(BC080499.1),ENSXETG00000010979(TCTEX1D4)" ENSMUSG00000014075(Tctex1d2) ENSG00000213123(TCTEX1D2) DRSC10797 K 0.395446703 -0.135752778 -0.140763961 -0.256543654 2.182186326 -0.551875906 FBgn0027081 Aats-thr Threonyl-tRNA synthetase http://flybase.net/reports/FBgn0027081.html "FBgn0022209, FBgn0032411" protein_coding_gene "0005524=ATP binding, 0004829=threonine-tRNA ligase activity" "0022008=neurogenesis, 0006435=threonyl-tRNA aminoacylation" 0005737=cytoplasm "l(2)k04203, CG5353, ThrRS, P539, 42/3, TRS, threonyl-tRNA synthetase" "IPR012676=TGS-like, IPR004154=Anticodon-binding, IPR006195=Aminoacyl-tRNA synthetase, class II, IPR012675=Beta-grasp domain, IPR002320=Threonine-tRNA ligase, class IIa, IPR002314=Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR018163=Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR004095=TGS, IPR012947=Threonyl/alanyl tRNA synthetase, SAD" CG5353 16-Dec-15 2015_12 ENSDARG00000013250(tars) YIL078W(THS1) WBGene00006617(tars-1) "ENSXETG00000009868(tars),ENSXETG00000020313(TARSL2)" ENSMUSG00000022241(Tars) "ENSG00000113407(TARS),ENSG00000185418(TARSL2)" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,neuroanatomy defective" "lysosome & larval fat body | somatic clone | cell autonomous,ganglion mother cell" FBgn0039291 CG13663 http://flybase.net/reports/FBgn0039291.html protein_coding_gene IPR019387=Uncharacterised domain SAYSvFN CG13663 16-Dec-15 2015_12 ENSDARG00000043687(si:ch211-59d15.9) viable FBgn0259982 l(2)35Cc lethal (2) 35Cc http://flybase.net/reports/FBgn0259982.html "FBgn0001979, FBgn0028860" protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding 0016272=prefoldin complex "BG:DS07295.5, l35Cc, l(2)br50, CG15266, br50" "IPR011599=Prefoldin alpha subunit, archaea-type, IPR009053=Prefoldin, IPR004127=Prefoldin alpha-like" CG15266 16-Dec-15 2015_12 ENSDARG00000019339(zgc:101894) WBGene00018071(F35H10.6) ENSMUSG00000001134(Uxt) ENSG00000126756(UXT) lethal FBgn0261278 grp grapes http://flybase.net/reports/FBgn0261278.html "FBgn0011598, FBgn0004632, FBgn0024213, FBgn0040478, FBgn0069054, FBgn0021840" protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0042060=wound healing, 0009314=response to radiation, 0016321=female meiosis chromosome segregation, 0007444=imaginal disc development, 0007349=cellularization, 0033314=mitotic DNA replication checkpoint, 0051299=centrosome separation, 0007095=mitotic G2 DNA damage checkpoint, 0001700=embryonic development via the syncytial blastoderm, 0051225=spindle assembly, 0006468=protein phosphorylation, 0007348=regulation of syncytial blastoderm mitotic cell cycle, 0000077=DNA damage checkpoint, 0007093=mitotic cell cycle checkpoint, 0007050=cell cycle arrest" "0005829=cytosol, 0005634=nucleus" "Pk?1, CHK1/Grapes, grps, DmChk1, grp(chk), Chk1, lemp, Checkpoint kinase 1, Dchk1, Chk1/Grapes, CG17161, dChk1, Grapes, checkpoint kinase 1, CHK1, 1C, Grp, chk1, Grp/DChk1, last empress, Protein kinase-like 36A, lethal (2) k15102, l(2)k15102, Pk36A" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG17161 16-Dec-15 2015_12 ENSDARG00000014385(chek1) WBGene00000498(chk-1) ENSXETG00000014861(CHEK1) ENSMUSG00000032113(Chek1) ENSG00000149554(CHEK1) " embryonic stage -- adult stage , adult stage && oogenesis stage , embryonic stage " oocyte

FBgn0023171 rnh1 ribonuclease H1 http://flybase.net/reports/FBgn0023171.html "FBgn0020291, FBgn0022077, FBgn0024594" protein_coding_gene "0004523=RNA-DNA hybrid ribonuclease activity, 0000287=magnesium ion binding, 0003676=nucleic acid binding" "RnH1, rnhl, l(2)43Fa, l(2)k07624, CG8729, l(2)43F1-5, l(2)k07409, 74/9, RNaseH1, RNase H1" "IPR011320=Ribonuclease H1, N-terminal, IPR002156=Ribonuclease H domain, IPR012337=Ribonuclease H-like domain, IPR017067=Ribonuclease H1, eukaryote, IPR009027=Ribosomal protein L9/RNase H1, N-terminal" CG8729 16-Dec-15 2015_12 ENSDARG00000042571(rnaseh1) YMR234W(RNH1) WBGene00004382(rnh-1.0) ENSXETG00000001212(RNASEH1) ENSMUSG00000020630(Rnaseh1) ENSG00000171865(RNASEH1) "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of prepupal stage,some die during prepupal stage,developmental rate defective,melanotic mass phenotype,viable" "stage P4(ii) prepupa,imaginal disc,embryonic/larval central nervous system,melanotic mass" FBgn0032358 Ppt2 Palmitoyl-protein Thioesterase 2 http://flybase.net/reports/FBgn0032358.html protein_coding_gene "0008474=palmitoyl-(protein) hydrolase activity, 0098599=palmitoyl hydrolase activity" 0098734=macromolecule depalmitoylation 0005764=lysosome "PPT-2, CG4851" "IPR029058=Alpha/Beta hydrolase fold, IPR030295=Lysosomal thioesterase PPT2, IPR002472=Palmitoyl protein thioesterase" CG4851 16-Dec-15 2015_12 "ENSDARG00000070883(ppt2),ENSDARG00000010782(zgc:55621),ENSDARG00000068826,ENSDARG00000068840(zgc:66024),ENSDARG00000014208(zgc:55413),ENSDARG00000068846(LOC100150238)" ENSXETG00000027741(PPT2) ENSMUSG00000015474(Ppt2) "ENSG00000168452,ENSG00000206329,ENSG00000206256" "viable,fertile" FBgn0036291 CG10681 http://flybase.net/reports/FBgn0036291.html protein_coding_gene IPR019371=Uncharacterised domain KxDL CG10681 16-Dec-15 2015_12 ENSDARG00000051934(zgc:91862) WBGene00015742(C13F10.2) ENSXETG00000023203(C19orf50) ENSG00000105700(C19orf50) viable FBgn0040232 cmet CENP-meta http://flybase.net/reports/FBgn0040232.html "FBgn0010574, FBgn0032355" protein_coding_gene "0003777=microtubule motor activity, 0008017=microtubule binding, 0008574=ATP-dependent microtubule motor activity, plus-end-directed, 0005524=ATP binding" "0007052=mitotic spindle organization, 0022008=neurogenesis, 0007018=microtubule-based movement, 0000278=mitotic cell cycle, 0051726=regulation of cell cycle, 0090307=mitotic spindle assembly, 0007080=mitotic metaphase plate congression" "0005871=kinesin complex, 0000940=condensed chromosome outer kinetochore, 0000776=kinetochore, 0000775=chromosome, centromeric region, 0005875=microtubule associated complex" "CENP-META, Cmet, KIF10, Cenp_E, cenp-meta, Cenp-M, DmCmet, l(2)04431, CG6392, CenpMeta, DmCmeta, CENPmeta, CENP-E, CENP-meta, Cenp-E, CENPE, CENP-Meta, KIF 10, CENP-E meta, Cenp-meta" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR019821=Kinesin motor domain, conserved site, IPR001752=Kinesin motor domain, IPR018159=Spectrin/alpha-actinin, IPR027640=Kinesin-like protein" CG6392 16-Dec-15 2015_12 YDL058W(USO1) ENSXETG00000021319(CENPE) ENSMUSG00000045328(Cenpe) ENSG00000138778(CENPE) "visible,conditional,heat sensitive,size defective,viable,fertile,lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,neuroanatomy defective" "eye,conditional,heat sensitive,embryonic/first instar larval cuticle,maternal effect,mitosis & nuclear chromosome,mitotic cell cycle,mitosis & nuclear chromosome | germ-line clone,mitotic anaphase | germline clone,centrosome | germline clone,mitotic metaphase | germline clone,condensed nuclear chromosome,spermatocyte,spindle microtubule,astral microtubule,spindle pole,ganglion mother cell,trichogen cell" DRSC03511 K 1.207261744 0.867315309 0.344867858 0.045488113 1.987819973 0.280797421 FBgn0265042 Irk1 Inwardly rectifying potassium channel 1 http://flybase.net/reports/FBgn0265042.html "FBgn0039060, FBgn0039061" protein_coding_gene "0015272=ATP-activated inward rectifier potassium channel activity, 0005242=inward rectifier potassium channel activity" "0045475=locomotor rhythm, 0035220=wing disc development, 0006813=potassium ion transport, 0042391=regulation of membrane potential" 0016021=integral component of membrane "irk1, Irk1, Dm_3R:100349, Inwardly rectifying potassium channel, Dir, CG13836, CG6747, dKirI, ir, Drosophila inward rectifier, DIR, Ir, Dm_3R:100326, CG44159" "IPR014756=Immunoglobulin E-set, IPR016449=Potassium channel, inwardly rectifying, Kir, IPR013518=Potassium channel, inwardly rectifying, Kir, cytoplasmic" CG44159 16-Dec-15 2015_12 "ENSDARG00000060259(zgc:162160),ENSDARG00000058985,ENSDARG00000061014,ENSDARG00000061636(LOC100334285),ENSDARG00000059747(si:dkey-106c17.3),ENSDARG00000062217(LOC557095),ENSDARG00000059822(LOC569146)" WBGene00002150(irk-2) "ENSXETG00000017827(),ENSXETG00000026072(KCNJ5),ENSXETG00000023557(KCNJ6),ENSXETG00000021717(KCNJ3),ENSXETG00000028069(),ENSXETG00000022975(),ENSXETG00000007492(KCNJ12),ENSXETG00000022962(KCNJ2),ENSXETG00000006360(KCNJ4)" "ENSMUSG00000042529(Kcnj12),ENSMUSG00000041695(Kcnj2),ENSMUSG00000044216(Kcnj4),ENSMUSG00000058743(Kcnj14)" "ENSG00000184185(KCNJ12),ENSG00000123700(KCNJ2),ENSG00000168135(KCNJ4),ENSG00000182324(KCNJ14),ENSG00000162728(KCNJ9),ENSG00000120457(KCNJ5)" FBgn0040253 Ugt86Dg Ugt86Dg http://flybase.net/reports/FBgn0040253.html FBgn0037866 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG17200-PA, CG17200, AC 006491G" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG17200 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0015321 Ubc4 Ubiquitin conjugating enzyme 4 http://flybase.net/reports/FBgn0015321.html protein_coding_gene "0070628=proteasome binding, 0004842=ubiquitin-protein transferase activity, 0031625=ubiquitin protein ligase binding" "0051726=regulation of cell cycle, 0000209=protein polyubiquitination" "E2, UbcD4, CG8284" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR009060=UBA-like, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site, IPR015940=Ubiquitin-associated domain" CG8284 16-Dec-15 2015_12 "ENSDARG00000013505(ube2k),ENSDARG00000071883" YDR177W(UBC1) WBGene00006715(ubc-20) ENSXETG00000012837(UBE2K) ENSMUSG00000029203(Ube2k) ENSG00000078140(UBE2K) viable FBgn0051613 His3:CG31613 His3:CG31613 http://flybase.net/reports/FBgn0051613.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006334=nucleosome assembly 0000786=nucleosome "His3, CG31613" "IPR000164=Histone H3/CENP-A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG31613 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" DRSC21267 IE -4.167786228 -3.384989702 -7.378306454 -6.017557947 -0.325687388 -1.108666666 FBgn0036659 CG9701 http://flybase.net/reports/FBgn0036659.html protein_coding_gene "0004553=hydrolase activity, hydrolyzing O-glycosyl compounds" 0005975=carbohydrate metabolic process Dmel_CG9701 "IPR013781=Glycoside hydrolase, catalytic domain, IPR018120=Glycoside hydrolase, family 1, active site, IPR001360=Glycoside hydrolase, family 1, IPR017853=Glycoside hydrolase superfamily" CG9701 16-Dec-15 2015_12 "ENSDARG00000016337(lctlb),ENSDARG00000036139(lctla)" "WBGene00017103(E02H9.5),WBGene00016848(C50F7.10)" "ENSXETG00000025031(),ENSXETG00000019306(),ENSXETG00000020469(GBA3),ENSXETG00000015904(LCTL)" ENSMUSG00000032401(Lctl) ENSG00000188501(LCTL) viable FBgn0027794 Lrpprc2 Leucine-rich pentatricopeptide repeat containing 2 http://flybase.net/reports/FBgn0027794.html protein_coding_gene 0005515=protein binding "0070129=regulation of mitochondrial translation, 0002082=regulation of oxidative phosphorylation, 1903108=regulation of transcription from mitochondrial promoter" "0035145=exon-exon junction complex, 0005739=mitochondrion" "CG14786, DmLrpprc2, EG:BACN32G11.3" IPR002885=Pentatricopeptide repeat CG14786 16-Dec-15 2015_12 WBGene00015425(C04E6.11) viable FBgn0051792 CG31792 http://flybase.net/reports/FBgn0051792.html FBgn0032736 protein_coding_gene "0005524=ATP binding, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity" "0006810=transport, 0055085=transmembrane transport" 0043190=ATP-binding cassette (ABC) transporter complex CG17338 "IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site" CG31792 16-Dec-15 2015_12 ENSDARG00000058953(abcc4) ENSXETG00000010958(ABCC4) ENSMUSG00000032849(Abcc4) ENSG00000125257(ABCC4) "viable,lethal" FBgn0035934 TrpA1 Transient receptor potential cation channel A1 ortholog http://flybase.net/reports/FBgn0035934.html protein_coding_gene "0015276=ligand-gated ion channel activity, 0033038=bitter taste receptor activity, 0097604=temperature-gated cation channel activity" "0006816=calcium ion transport, 0023041=neuronal signal transduction, 0009416=response to light stimulus, 0050965=detection of temperature stimulus involved in sensory perception of pain, 0007602=phototransduction, 0006812=cation transport, 0001580=detection of chemical stimulus involved in sensory perception of bitter taste, 0050968=detection of chemical stimulus involved in sensory perception of pain, 0043052=thermotaxis, 0007638=mechanosensory behavior, 0050960=detection of temperature stimulus involved in thermoception, 0046957=negative phototaxis, 0050850=positive regulation of calcium-mediated signaling, 0010378=temperature compensation of the circadian clock, 0034220=ion transmembrane transport, 0034605=cellular response to heat, 0040040=thermosensory behavior" 0034703=cation channel complex "dTRPA, dTrpA, TRPA, transient-receptor-potential A1, Transient receptor potential A 1, trpA1, TrpA, dTrpA1, Trpa1, dTRPA1, Transient receptor potential A1, ANKTM1, DmTRPA1, CG5751, dtrpA1, Trp1A, Transient receptor potential cation channel, Anktm1, CG5761, TRPA1, CT18073, dANKTM1" "IPR005821=Ion transport domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR030288=Transient receptor potential ankyrin 1 channel" CG5751 16-Dec-15 2015_12 "ENSDARG00000031875(trpa1b),ENSDARG00000016699(trpa1a)" WBGene00007801(trpa-1) ENSXETG00000015979(TRPA1) ENSMUSG00000032769(Trpa1) ENSG00000104321(TRPA1) "courtship behavior defective,male,heat sensitive,conditional,neuroanatomy defective,mating behavior defective,female limited,locomotor rhythm defective,taste perception defective,recessive,song defective,somatic clone,behavior defective,paralytic,neurophysiology defective,memory defective,circadian behavior defective,mating defective,learning defective,sleep defective,starvation stress response defective,tarsal response defective,locomotor behavior defective,smell perception defective,chemical sensitive,feeding behavior defective,male limited,pain response defective,proboscis extension reflex defective,progressive,chemosensitive behavior defective,thermotaxis behavior defective,female,visible,partially lethal - majority die,some die during pupal stage,lethal,phototaxis defective,heat stress response defective,temperature response defective" "dendrite | third instar larval stageGMR.PF,LNv neuron | third instar larval stage,neuromuscular junction | heat sensitive,indirect flight muscle motor neuron MN5,heat sensitive,dendrite | heat sensitivefutsch-C380,large labellar taste bristle,proboscis,adult olfactory receptor neuron ab11a,mesothoracic tergum,AC thermosensory neuron,intermediate labellar taste bristle" FBgn0015031 cype cyclope http://flybase.net/reports/FBgn0015031.html "FBgn0010553, FBgn0031699, FBgn0040947, FBgn0063275" protein_coding_gene 0004129=cytochrome-c oxidase activity "0006123=mitochondrial electron transport, cytochrome c to oxygen" "0005751=mitochondrial respiratory chain complex IV, 0005811=lipid particle, 0005739=mitochondrion" "Subunit VIc, BcDNA:GH04604, COXVIc, Cype, Cyc, Cytochrome c oxidase subunit 6C, Cytochrome c oxidase VIc, Cytochrome c oxidase Polypeptide VIc, COX6C, COXH, l(2)03771, CG14028, CG18323, Cyclope, cyc, VIc, Cytochrome c oxidase polypeptide VIc" IPR004204=Cytochrome c oxidase subunit 6C CG14028 16-Dec-15 2015_12 ENSDARG00000038577(si:ch211-239j9.2) ENSXETG00000025937(cox6c) "ENSMUSG00000014313(Cox6c),ENSMUSG00000066491(Gm6265)" ENSG00000164919(COX6C) "lethal,recessive,partially lethal - majority die,visible,dominant,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,developmental rate defective,wild-type,maternal effect,semidominant,viable" "embryonic head,embryonic/first instar larval cuticle,denticle belt,ovary,germline clone,tergite,leg,wing,adult thorax,eye,ommatidium,macrochaeta,somatic clone,wing margin bristle,interommatidial bristle,supernumerary,amnioserosa,maternal effect,filzkorper,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,thorax,head,mesothoracic tergum,trichogen cell" FBgn0016131 Cdk4 Cyclin-dependent kinase 4 http://flybase.net/reports/FBgn0016131.html "FBgn0004458, FBgn0010600, FBgn0010696, FBgn0022125" protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0030332=cyclin binding, 0004693=cyclin-dependent protein serine/threonine kinase activity" "0007005=mitochondrion organization, 0007259=JAK-STAT cascade, 0007350=blastoderm segmentation, 0051726=regulation of cell cycle, 0000278=mitotic cell cycle, 0006468=protein phosphorylation, 0001558=regulation of cell growth, 0016049=cell growth, 0008283=cell proliferation, 0007424=open tracheal system development" "l(2)s4639, Cdk4/6, 8-6, Pk53C, l(2)0671, CG5072, Protein kinase-like 53C, l(2)sh0671, cdk4, DmCdk4, Pk?7, cdk4/6, CDK4/6, Cyclin-dependent kinase 4/6, l(2)k06503, dCdk4, cyclin-dependent kinase 4, CDK4, cdk, l(2)05428" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG5072 16-Dec-15 2015_12 "ENSDARG00000063466(zgc:153726),ENSDARG00000070228(si:ch211-234f14.1),ENSDARG00000030163(LOC569515)" WBGene00000406(cdk-4) ENSXETG00000018529(CDK6) "ENSMUSG00000040274(Cdk6),ENSMUSG00000006728(Cdk4)" "ENSG00000105810(CDK6),ENSG00000135446(CDK4)" embryonic stage -- adult stage "lethal,recessive,viable,fertile,maternal effect,poor,sterile,female,small body,decreased cell number,somatic clone,increased cell size,radiation sensitive,size defective,visible" "abdominal 5 ventral denticle belt,germline clone,maternal effect,embryonic/first instar larval cuticle,segment,head,adult,wing,abdominal 6 ventral denticle belt,rescuable maternal effect,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic head,tracheal branch primordium,dorsal trunk primordium,cell cycle,embryo,denticle belt,mesothoracic tergum" DRSC07358 IE -1.933465771 -2.656059343 -2.481610609 -3.220110809 1.177203104 0.1157009 FBgn0016791 csw::Src64B csw::Src64B http://flybase.net/reports/FBgn0016791.html engineered_fusion_gene unnamed 16-Dec-15 2015_12 visible "eye,cone cell,precursor,photoreceptor cell R7,ectopic,supernumerary,embryonic/larval tracheocyte,ectopic | embryonic stage,ectoderm,ventral,tracheal branch primordium,embryonic myoblast,cardioblast | embryonic stage,chorion,dorsal appendage,embryo,wing vein,mesoderm,terminal tracheal cell,embryonic/larval tracheal system" FBgn0001376 l(1)devl lethal decreased volume optic lobes http://flybase.net/reports/FBgn0001376.html gene "HM38, l(1)2Bg, l(1)HM38" 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" embryonic/larval brain FBgn0263397 Ih Ih channel http://flybase.net/reports/FBgn0263397.html "FBgn0047303, FBgn0050068, FBgn0028428, FBgn0027105, FBtr0089936, FBpp0088875" protein_coding_gene "0005249=voltage-gated potassium channel activity, 0005221=intracellular cyclic nucleotide activated cation channel activity, 0005244=voltage-gated ion channel activity" "0008340=determination of adult lifespan, 0014059=regulation of dopamine secretion, 0007637=proboscis extension reflex, 0050802=circadian sleep/wake cycle, sleep, 0045938=positive regulation of circadian sleep/wake cycle, sleep, 0045475=locomotor rhythm, 1903294=regulation of glutamate secretion, neurotransmission, 0016057=regulation of membrane potential in photoreceptor cell, 0055085=transmembrane transport, 0006813=potassium ion transport, 0071484=cellular response to light intensity, 0071632=optomotor response" "0005886=plasma membrane, 0016020=membrane" "Ih channel, Ih-channel, putative-voltage-and-cyclic-nucleotide-gated-ion-channel, DMIH, BcDNA:GH25778, I[[h]], Drosophila melanogaster I[[h]]-channel, CG8585, CR30068, putative Ih-channel, DmIh" "IPR018488=Cyclic nucleotide-binding, conserved site, IPR003938=Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR014710=RmlC-like jelly roll fold, IPR005821=Ion transport domain, IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like, IPR013621=Ion transport N-terminal" CG8585 16-Dec-15 2015_12 "ENSMUSG00000020331(Hcn2),ENSMUSG00000032338(Hcn4),ENSMUSG00000021730(Hcn1),ENSMUSG00000028051(Hcn3)" "ENSG00000138622(HCN4),ENSG00000099822(HCN2),ENSG00000164588(HCN1),ENSG00000143630(HCN3)" FBgn0004516 Gad1 Glutamic acid decarboxylase 1 http://flybase.net/reports/FBgn0004516.html "FBgn0001088, FBgn0001110, FBgn0016015" protein_coding_gene "0004351=glutamate decarboxylase activity, 0030170=pyridoxal phosphate binding" "0045213=neurotransmitter receptor metabolic process, 0007528=neuromuscular junction development, 0042136=neurotransmitter biosynthetic process, 0008355=olfactory learning, 0006538=glutamate catabolic process, 0008345=larval locomotory behavior, 0009612=response to mechanical stimulus, 0007416=synapse assembly, 0009449=gamma-aminobutyric acid biosynthetic process" 0005829=cytosol "dgad1, vesicular glutamic acid decarboxylase, gad, CG14994, l(3)64An, dGad1, GAD[[1]], GAD-1, Glb, GAD1, glutamic acid decarboxylase-1, Glutamic acid decarboxylase-1, gad1, glutamatic acid decarboxylase, Gad, DGad1, l(3)SH10, DGAD1, GAD, GABA synthetase, glutamic acid decarboxylase, Glutamic acid decarboxylase" "IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase, IPR021115=Pyridoxal-phosphate binding site" CG14994 16-Dec-15 2015_12 "ENSDARG00000027419(gad1),ENSDARG00000010744(LOC100329827),ENSDARG00000015537" WBGene00006762(unc-25) "ENSXETG00000018848(GAD1),ENSXETG00000005863()" "ENSMUSG00000070880(Gad1),ENSMUSG00000026787(Gad2)" "ENSG00000128683(GAD1),ENSG00000136750(GAD2)" "neurophysiology defective,locomotor behavior defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,flight defective,viable,smell perception defective,behavior defective" "neuromuscular junction,bouton,mushroom body anterior paired lateral cell" FBgn0024814 Clc Clathrin light chain http://flybase.net/reports/FBgn0024814.html protein_coding_gene "0032050=clathrin heavy chain binding, 0005198=structural molecule activity" "0007269=neurotransmitter secretion, 0072583=clathrin-mediated endocytosis, 0006886=intracellular protein transport, 0016183=synaptic vesicle coating" "0030130=clathrin coat of trans-Golgi network vesicle, 0005737=cytoplasm, 0030125=clathrin vesicle coat, 0072686=mitotic spindle, 0030135=coated vesicle, 0030132=clathrin coat of coated pit, 0030136=clathrin-coated vesicle, 0071439=clathrin complex, 0008021=synaptic vesicle, 0005905=coated pit, 0005886=plasma membrane, 0005938=cell cortex" "CG6948, clathrin-light-chain, Clathrin, clc, clc1, CLC, clathrin light-chain, clathrin light chain, Clathrin Light Chain, clathrin" IPR000996=Clathrin light chain CG6948 16-Dec-15 2015_12 "ENSDARG00000052368,ENSDARG00000045618(clta)" WBGene00020246(clic-1) "ENSXETG00000007168(clta),ENSXETG00000006744(cltb)" "ENSMUSG00000047547(Cltb),ENSMUSG00000028478(Clta)" "ENSG00000175416(CLTB),ENSG00000122705(CLTA)" viable FBgn0261823 Asx Additional sex combs http://flybase.net/reports/FBgn0261823.html "FBgn0000142, FBgn0020770" protein_coding_gene "0003682=chromatin binding, 0003677=DNA binding, 0035800=deubiquitinase activator activity" "0045498=sex comb development, 0006342=chromatin silencing, 0007469=antennal development, 2000152=regulation of ubiquitin-specific protease activity, 0010468=regulation of gene expression, 0035522=monoubiquitinated histone H2A deubiquitination, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0035186=syncytial blastoderm mitotic cell cycle, 0001709=cell fate determination" "0000785=chromatin, 0005634=nucleus, 0035517=PR-DUB complex" "FBgn0261823, ASX, Additional Sex Combs, xen, xenicid, Additionnal sex comb, CG8787, additional sex combs, Additional sex comb" "IPR026905=Protein ASX-like, PHD domain, IPR024811=Polycomb protein ASX/ASX-like, IPR028020=ASX homology domain, IPR024814=Polycomb protein ASX" CG8787 16-Dec-15 2015_12 ENSDARG00000036956(si:dkey-202m22.4) ENSXETG00000003167(ASXL2) ENSMUSG00000045215(Asxl3) "ENSG00000143970(ASXL2),ENSG00000171456(ASXL1)" " embryonic stage -- adult stage , embryonic stage | blastoderm , embryonic stage | stage >5 , adult stage && oogenesis stage , embryonic stage " "

anterior ,

posterior , organism | ubiquitous

, nurse cell

, ventral neurogenic region

, central nervous system

" " embryonic stage , embryonic stage | stage >=5 " " central nervous system

, ventral neurogenic region

, organism

" FBgn0033153 Gadd45 Gadd45 http://flybase.net/reports/FBgn0033153.html FBgn0062909 protein_coding_gene "0051726=regulation of cell cycle, 0046662=regulation of oviposition, 0007254=JNK cascade" 0005634=nucleus "GADD45, BcDNA:RH70774, CG11086, growth arrest and DNA damage-inducible gene 45, D-GADD45, GG1086" "IPR024824=Growth arrest and DNA damage-inducible protein GADD45, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45" CG11086 16-Dec-15 2015_12 "ENSDARG00000044676(LOC797032),ENSDARG00000016725(zgc:85869),ENSDARG00000019417(gadd45g),ENSDARG00000069991(gadd45ab),ENSDARG00000043581(gadd45aa),ENSDARG00000027744(gadd45ba),ENSDARG00000013576(gadd45bb)" "ENSXETG00000026537(gadd45g),ENSXETG00000012392(gadd45a),ENSXETG00000003717(GADD45B)" "ENSMUSG00000021453(Gadd45g),ENSMUSG00000036390(Gadd45a),ENSMUSG00000015312(Gadd45b)" "ENSG00000130222(GADD45G),ENSG00000116717(GADD45A),ENSG00000099860(GADD45B)" "lethal,long lived,locomotor rhythm defective,RU486 conditional,viable" "egg chamber,nurse cell,follicle cell,dorsal appendage,chorion" FBgn0032151 nAChRë±6 nicotinic Acetylcholine Receptor ë±6 http://flybase.net/reports/FBgn0032151.html FBgn0046810 protein_coding_gene 0004889=acetylcholine-activated cation-selective channel activity "0007271=synaptic transmission, cholinergic, 0017085=response to insecticide, 0046716=muscle cell cellular homeostasis, 0006812=cation transport" "0045211=postsynaptic membrane, 0005892=acetylcholine-gated channel complex, 0016021=integral component of membrane" "das, CT13662, resistant to spinosyns, Nicotinic Acetylcholine Receptor 30D, BcDNA:GH01410, Dalpha6, nAChRalpha-30D, alpha6 nicotinic acetylcholine receptor subunit, CG4128, nAChRAlpha-30D, resistance to spinosyn, rsn, nAChR alpha 6, nAChRalpha6, nAChRalpha, nAChR, nAcRalpha-30D, alpha6, nicotinic Acetylcholine Receptor alpha 30D" "IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR002394=Nicotinic acetylcholine receptor, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG4128 16-Dec-15 2015_12 "ENSDARG00000037427(si:ch211-39a7.1),ENSDARG00000035785(chrna7),ENSDARG00000037424,ENSDARG00000033954" WBGene00000055(acr-16) "ENSXETG00000016395(),ENSXETG00000018003()" ENSMUSG00000030525(Chrna7) "ENSG00000175344(CHRNA7),ENSG00000166664(CHRFAM7A)" "chemical resistant,viable,fertile,neurophysiology defective,lethal" ventral nerve cord FBgn0035625 Blimp-1 Blimp-1 http://flybase.net/reports/FBgn0035625.html protein_coding_gene "0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003676=nucleic acid binding, 0046872=metal ion binding" "0071390=cellular response to ecdysone, 0035152=regulation of tube architecture, open tracheal system, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048869=cellular developmental process" "0005634=nucleus, 0005737=cytoplasm" "dBlimp-1, CG5249, dBlimp1, blimp-1" "IPR016608=PR domain zinc finger protein 1, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR001214=SET domain" CG5249 16-Dec-15 2015_12 ENSDARG00000002445(prdm1a) WBGene00003847(blmp-1) ENSXETG00000008674(prdm1) ENSMUSG00000038151(Prdm1) ENSG00000057657(PRDM1) "lethal - all die before end of pupal stage,some die during pupal stage" dorsal trunk primordium FBgn0029848 Btnd Biotinidase http://flybase.net/reports/FBgn0029848.html protein_coding_gene "0016811=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" "0009408=response to heat, 0006807=nitrogen compound metabolic process, 0071110=histone biotinylation, 0018054=peptidyl-lysine biotinylation" "CT12113, Btd, biotinidase, CG3599, BTD" "IPR012101=Biotinidase, eukaryotic, IPR003010=Carbon-nitrogen hydrolase" CG3599 16-Dec-15 2015_12 ENSDARG00000006926 "ENSXETG00000000104(BC087969.1),ENSXETG00000008991(BTD)" "ENSMUSG00000021900(Btd),ENSMUSG00000037440(Vnn1),ENSMUSG00000020010(Vnn3)" "ENSG00000169814(BTD),ENSG00000112299(VNN1),ENSG00000112303(VNN2),ENSG00000093134" "short lived,heat stress response defective,male limited,partially lethal - majority die,some die during pupal stage,lethal,recessive" FBgn0265784 CrebB Cyclic-AMP response element binding protein B http://flybase.net/reports/FBgn0265784.html "FBgn0014467, FBgn0004972, FBgn0014468" protein_coding_gene "0003677=DNA binding, 0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0045475=locomotor rhythm, 0072375=medium-term memory, 0045187=regulation of circadian sleep/wake cycle, sleep, 0007616=long-term memory, 0030431=sleep, 0007623=circadian rhythm, 0007611=learning or memory, 0007622=rhythmic behavior, 0040040=thermosensory behavior, 2000253=positive regulation of feeding behavior, 0007528=neuromuscular junction development, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "cAMP-response element-binding protein, S162, cAMP-regulated enhancer-binding protein, lethal(1)17Af, dCREB, dCREB2b, CrebB-17A, dCREB-2a, dCbz, dcreb2-b, CG6103, Creb, CrebB17-A, dCreb2, dCREB2-a, dCREB-2, Creb17A, dCREB2, CREB-B, cyclic AMP response element binding protein, dCreb2-b, DM9, cAMP response-element binding protein, Creb B 17A, dCREB2-b, CrebB-17B, Creb2, blocker, CREB2, Cyclic-AMP response element binding protein B at 17B, dCREB-B, activator, cAMP-response element binding protein, CREB2b, Creb2-b, Creb2.b, l(1)17Af, CRE-BP, cAMP response element-binding protein, dCrebB2, dCREB2a, CREB, CREB2a, CREB-b, Creb2b, Cyclic-AMP response element binding protein B at 17A" "IPR003102=Coactivator CBP, pKID, IPR001630=cAMP response element binding (CREB) protein, IPR004827=Basic-leucine zipper domain" CG6103 16-Dec-15 2015_12 "ENSDARG00000023217(si:dkey-177e13.4),ENSDARG00000044301(atf1),ENSDARG00000041455,ENSDARG00000053586(creb1)" "ENSXETG00000016392(creb1),ENSXETG00000007299(atf1)" "ENSMUSG00000025958(Creb1),ENSMUSG00000063889(Crem),ENSMUSG00000023027(Atf1)" "ENSG00000118260(CREB1),ENSG00000095794(CREM),ENSG00000123268(ATF1)" " adult stage , embryonic stage&&larval stage&&pupal stage&&adult stage " adult head

DRSC20232 EK 1.171535118 -0.238027572 1.798951786 0.01912478 1.411067395 1.552254913 FBgn0027525 CG7686 http://flybase.net/reports/FBgn0027525.html protein_coding_gene BcDNA:LD21529 IPR007307=Low temperature viability protein CG7686 16-Dec-15 2015_12 WBGene00011944(T23D8.3) ENSXETG00000009783(LTV1) ENSMUSG00000019814(Ltv1) ENSG00000135521(LTV1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051116 ClC-a Chloride channel-a http://flybase.net/reports/FBgn0051116.html "FBgn0037951, FBgn0037952" protein_coding_gene "0005254=chloride channel activity, 0005247=voltage-gated chloride channel activity" "0006821=chloride transport, 0055085=transmembrane transport" "0016020=membrane, 0015629=actin cytoskeleton" "DmClC-2, CG14726, FBgn0037951, CG31116, DmClC-a, CG6942, DmClCa, CLC-2, Clc-a" "IPR000644=CBS domain, IPR001807=Chloride channel, voltage gated, IPR014743=Chloride channel, core" CG31116 16-Dec-15 2015_12 "ENSDARG00000062427,ENSDARG00000062084(si:dkey-14o18.5),ENSDARG00000012269(LOC567478)" WBGene00000530(clh-3) ENSXETG00000017289(CLCN2) "ENSMUSG00000022843(Clcn2),ENSMUSG00000029862(Clcn1)" "ENSG00000114859(CLCN2),ENSG00000188037(CLCN1)" FBgn0050037 CG30037 http://flybase.net/reports/FBgn0050037.html FBgn0033671 protein_coding_gene "0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" 0006486=protein glycosylation 0016020=membrane CG8976 "IPR002659=Glycosyl transferase, family 31" CG30037 16-Dec-15 2015_12 "ENSDARG00000018971(b3gnt5),ENSDARG00000004396(zgc:101733)" WBGene00019539 "ENSXETG00000016205(B3GALT1),ENSXETG00000004532(B3GALT2),ENSXETG00000004536(BC075347.1),ENSXETG00000002261(),ENSXETG00000011652(),ENSXETG00000006113(),ENSXETG00000006114(),ENSXETG00000006118(),ENSXETG00000006123(),ENSXETG00000002237(B3GNT1)" viable FBgn0031930 CG7025 http://flybase.net/reports/FBgn0031930.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "IPR003146=Proteinase inhibitor, carboxypeptidase propeptide, IPR000834=Peptidase M14, carboxypeptidase A, IPR009020=Proteinase inhibitor, propeptide" CG7025 16-Dec-15 2015_12 "ENSDARG00000021339(cpa5),ENSDARG00000030915(cpa1),ENSDARG00000043722(cpa4),ENSDARG00000010146(cpa2)" "WBGene00020281(T06A4.1),WBGene00021213(Y18H1A.9)" "ENSXETG00000025544(),ENSXETG00000016396()" "ENSMUSG00000011463(Cpb1),ENSMUSG00000071553(Cpa2),ENSMUSG00000054446(Cpa1),ENSMUSG00000029788(Cpa5),ENSMUSG00000001865(Cpa3),ENSMUSG00000042501(Cpa6),ENSMUSG00000021999(Cpb2)" "ENSG00000158516(CPA2),ENSG00000091704(CPA1),ENSG00000158525(CPA5),ENSG00000153002(CPB1)" viable FBgn0004867 RpS2 Ribosomal protein S2 http://flybase.net/reports/FBgn0004867.html "FBgn0010266, FBgn0013522, FBgn0022202, FBgn0025306" protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" 0006412=translation "0022627=cytosolic small ribosomal subunit, 0000228=nuclear chromosome, 0005730=nucleolus, 0005840=ribosome, 0005737=cytoplasm" "String of pearls, Dm01335, unnamed, Rp S2, dS2, S2, sop, S2 ribosomal protein, l(2)k04603, RpS2, string of pearls, 40S ribosomal protein S2, ribosomal protein S2, Ribosomal protein S2, CG5920, anon-EST:Posey202, Ribosome RS2, l(2)03848" "IPR005324=Ribosomal protein S5, C-terminal, IPR000851=Ribosomal protein S5, IPR014720=Double-stranded RNA-binding domain, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR013810=Ribosomal protein S5, N-terminal, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup, IPR005711=Ribosomal protein S5, eukaryotic/archaeal, IPR018192=Ribosomal protein S5, N-terminal, conserved site" CG5920 16-Dec-15 2015_12 ENSDARG00000057250 YGL123W(RPS2) WBGene00004471(rps-2) ENSXETG00000007220(rps2) "ENSMUSG00000044533(Rps2),ENSMUSG00000057244(Gm6139),ENSMUSG00000074034(Gm5921),ENSMUSG00000075515(Rps2-ps6),ENSMUSG00000068604(Gm8225),ENSMUSG00000062365(Gm5978)" "ENSG00000140988(RPS2),ENSG00000197149" " oogenesis stage && adult stage | female , oogenesis stage , adult stage | female , adult stage && oogenesis stage , embryonic stage " " ovary

,

ubiquitous , nurse cell

" "visible,partially lethal - majority die,lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "anterior crossvein,wing,macrochaeta,stage S5 oocyte,ovary" DRSC03614 IEK -1.480544164 -1.946626878 3.165610992 -5.606791895 1.395854719 3.029395701 FBgn0037391 CG2017 http://flybase.net/reports/FBgn0037391.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "CG 2017, GP-1 related" "IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal" CG2017 16-Dec-15 2015_12 "ENSDARG00000071059(si:ch211-151i8.2),ENSDARG00000071078,ENSDARG00000010632" WBGene00011449(T04H1.2) ENSMUSG00000023952(Gtpbp2) ENSG00000172432(GTPBP2) "viable,fertile,neuroanatomy defective" "anterior fascicle & synapse,intersegmental nerve" FBgn0000557 Ef1ë±100E Elongation factor 1ë±100E http://flybase.net/reports/FBgn0000557.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003746=translation elongation factor activity" "0022008=neurogenesis, 0006412=translation, 0006414=translational elongation" "0005853=eukaryotic translation elongation factor 1 complex, 0005737=cytoplasm, 0005811=lipid particle" "elongation factor 1alpha 100E, elongation factor 1-alpha F2, eEF1alpha, EF-1alpha F2, ef-1alpha, EF1-a 100E, Ef1a48, EF-1alpha, EF1-alpha, F2, Elongation factor 1-alpha, Ef1alpha2, CG1873, EF1alpha, EF1a, Ef1 alpha100E, Efla2, EF-1, EF1alpha100, S, Ef1a-100E, Ef1alpha100E" "IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR031157=Tr-type G domain, conserved site, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR004539=Translation elongation factor EF1A, eukaryotic/archaeal, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR004160=Translation elongation factor EFTu/EF1A, C-terminal" CG1873 16-Dec-15 2015_12 "ENSDARG00000020850(ef1a),ENSDARG00000039502(zgc:73138),ENSDARG00000069951(zgc:110335),ENSDARG00000069952,ENSDARG00000006838(zgc:92085)" "YBR118W(TEF2),YPR080W(TEF1)" WBGene00001169(eft-4) "ENSXETG00000001182(EEF1A1),ENSXETG00000019567(Q5I0S9_XENTR),ENSXETG00000022604(eef1a1)" "ENSMUSG00000037742(Eef1a1),ENSMUSG00000016349(Eef1a2)" "ENSG00000156508(EEF1A1),ENSG00000101210(EEF1A2)" " pupal stage | late , adult stage " "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0031437 Arpc5 "Actin-related protein 2/3 complex, subunit 5" http://flybase.net/reports/FBgn0031437.html protein_coding_gene "0003779=actin binding, 0005200=structural constituent of cytoskeleton" "0000902=cell morphogenesis, 0034314=Arp2/3 complex-mediated actin nucleation, 0006909=phagocytosis, 0030833=regulation of actin filament polymerization" "0005885=Arp2/3 protein complex, 0030027=lamellipodium" "CG9881, p16-arc, Arpc5, p16, ARPC5, ArpC5, p16-ARC, P16-ARC" IPR006789=Actin-related protein 2/3 complex subunit 5 CG9881 16-Dec-15 2015_12 "ENSDARG00000019062(arpc5b),ENSDARG00000039142,ENSDARG00000035433(arpc5lb),ENSDARG00000041720(arpc5la)" YIL062C(ARC15) "WBGene00000205(arx-7),WBGene00016729(C46H11.3)" "ENSXETG00000024664(arpc5),ENSXETG00000016842(arpc5l)" "ENSMUSG00000008475(Arpc5),ENSMUSG00000026755(Arpc5l)" "ENSG00000136950(ARPC5L),ENSG00000162704(ARPC5)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033474 CG1407 http://flybase.net/reports/FBgn0033474.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005886=plasma membrane "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG1407 16-Dec-15 2015_12 "ENSDARG00000058178(LOC100001188),ENSDARG00000055066(zgc:162723),ENSDARG00000034757(zdhhc2),ENSDARG00000071872(zdhhc15b)" YNL326C(PFA3) WBGene00014075(ZK757.4) "ENSXETG00000004578(ZDHHC15),ENSXETG00000027185(zdhhc20)" "ENSMUSG00000039470(Zdhhc2),ENSMUSG00000021969(Zdhhc20),ENSMUSG00000033906(Zdhhc15)" "ENSG00000104219(ZDHHC2),ENSG00000180776(ZDHHC20),ENSG00000102383(ZDHHC15)" "viable,fertile" FBgn0023174 Prosë_2 Proteasome ë_2 subunit http://flybase.net/reports/FBgn0023174.html "FBgn0002419, FBgn0025245, FBgn0025254" protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0006974=cellular response to DNA damage stimulus" "0000502=proteasome complex, 0019774=proteasome core complex, beta-subunit complex, 0005839=proteasome core complex" "anon-EST:fe1G6, beta2 subunit, Beta-2, prosbeta, DTS-7, b2, Prosbeta 2, 20S proteasome, beta-2, prosbeta2, Prosbeta2, beta2, beta 2, unnamed, anon-fast-evolving-1G6, PROSbeta2, beta2 proteosome subunit, b2 subunit, CG3329, l(3)DTS7, Dts7, anon-EST:fe1E6, Proteasome beta2 subunit, 3329, Prosbeta, beta2_dm, 20s proteasome, anon-fast-evolving-1E6, DTS7" "IPR023333=Proteasome B-type subunit, IPR024689=Proteasome beta subunit, C-terminal, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000243=Peptidase T1A, proteasome beta-subunit, IPR001353=Proteasome, subunit alpha/beta, IPR016050=Proteasome beta-type subunit, conserved site" CG3329 16-Dec-15 2015_12 ENSDARG00000037962(psmb7) YOR157C(PUP1) WBGene00003948(pbs-2) ENSXETG00000011463(PSMB7) ENSMUSG00000026750(Psmb7) ENSG00000136930(PSMB7) embryonic stage -- adult stage "neuroanatomy defective,wild-type,lethal,dominant,heat sensitive,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere of eye photoreceptor cell,macrochaeta,microchaeta,tormogen cell,ectopic,thecogen cell,trichogen cell,eo neuron,imaginal disc,heat sensitive,adult abdomen,wing vein,eye,ommatidium,multivesicular body | supernumerary | heat sensitiveGMR.PF,autophagic vacuole | supernumerary | heat sensitiveGMR.PF,eye photoreceptor cell" DRSC11257 IEK -2.22680727 -2.148158293 -1.43370878 -3.617696514 0.731796467 1.771613459 FBgn0027259 Kmn1 kinetochore Mis12-Ndc80 network component 1 http://flybase.net/reports/FBgn0027259.html "FBgn0030312, FBgn0066829" protein_coding_gene "0051726=regulation of cell cycle, 0022008=neurogenesis, 0007080=mitotic metaphase plate congression, 0007079=mitotic chromosome movement towards spindle pole, 0007059=chromosome segregation" "0000776=kinetochore, 0031617=NMS complex, 0031262=Ndc80 complex" "CT4038, CG1558, Nsl1, Nsl1-related protein, l(1)G0237, anon-WO03040301.201, nsl1, lethal (1) G0237, dmNsl1R" CG1558 16-Dec-15 2015_12 "mitotic cell cycle defective,viable,fertile,uncoordinated,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed nuclear chromosome,metaphase,nucleus,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001222 Hsf Heat shock factor http://flybase.net/reports/FBgn0001222.html "FBgn0010529, FBgn0020929" protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding" "0043388=positive regulation of DNA binding, 0045893=positive regulation of transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0009408=response to heat, 0045892=negative regulation of transcription, DNA-templated, 0050832=defense response to fungus, 0022008=neurogenesis, 0042742=defense response to bacterium, 0031427=response to methotrexate" "0000785=chromatin, 0005700=polytene chromosome, 0005634=nucleus" "heat shock transcription factor, dHSF, heat-shock transcription factor, Heat-shock factor, HSF, heat shock factor, l(2)03091, HSF1, DmHSF, D-HSF, CG5748, dHSFa, HSFa, DmHSFa, hsf, Dm-Hsf, Heat-Shock Factor, heat shock transcription factor 1" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR027725=Heat shock transcription factor family, IPR000232=Heat shock factor (HSF)-type, DNA-binding, IPR010542=Vertebrate heat shock transcription factor, C-terminal domain" CG5748 16-Dec-15 2015_12 "ENSDARG00000008818(hsf1),ENSDARG00000013251(hsf4)" YGL073W(HSF1) WBGene00002004(hsf-1) "ENSXETG00000009764(TEgg106g13.1),ENSXETG00000023290(HSF2),ENSXETG00000005693(HSF1)" ENSMUSG00000022556(Hsf1) "ENSG00000185122(HSF1),ENSG00000025156(HSF2)" "lethal,recessive,increased mortality,wild-type,female sterile,stress response defective,dominant,female sterile germline-dependent,germline clone,lethal - all die before end of larval stage,some die during larval stage,fertile,viable,heat stress response defective,heat sensitive,immune response defective,neurophysiology defective,neuroanatomy defective" "salivary gland,egg chamber,nurse cell,polytene chromosome,ganglion mother cell" FBgn0013726 pnut peanut http://flybase.net/reports/FBgn0013726.html "FBgn0010304, FBgn0010515" protein_coding_gene "0005525=GTP binding, 0008017=microtubule binding, 0031625=ubiquitin protein ligase binding, 0003779=actin binding, 0003924=GTPase activity, 0042803=protein homodimerization activity" "0043065=positive regulation of apoptotic process, 0007349=cellularization, 0000281=mitotic cytokinesis, 0000915=actomyosin contractile ring assembly, 0006915=apoptotic process" "0070938=contractile ring, 0031105=septin complex, 0032154=cleavage furrow, 0005940=septin ring, 0005739=mitochondrion, 0045172=germline ring canal, 0005886=plasma membrane, 0045171=intercellular bridge, 0005875=microtubule associated complex" "anon-EST:Liang-2.18, CG8705, Peanut, l(2)02502, septin[Pnut], unnamed, Septin, E(sina)8, E(sina)44C, Septin 3, Pnut, clone 2.18, Enhancer of seven in absentia 8, septin, PNUT" "IPR030379=Septin-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR016491=Septin" CG8705 16-Dec-15 2015_12 "ENSDARG00000019649(sept7b),ENSDARG00000052673(LOC100000597)" YLR314C(CDC3) WBGene00006793(unc-59) ENSXETG00000013112() ENSMUSG00000001833(Sept7) "ENSG00000122545(SEPT7),ENSG00000214765" " larval stage | third instar , embryonic stage , adult stage " " photoreceptor cell | presumptive

, central nervous system

, follicle cell | basal " "lethal,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,viable,fertile,wild-type,cytokinesis defective,lethal - all die before end of pupal stage,some die during pupal stage,visible,partially lethal - majority die" "egg,germline clone,germarium region 1,embryonic/first instar larval cuticle,denticle belt,embryonic head,actin filament | embryonic stage | germline clone,ventral furrow & actin filament | germ-line clone,nucleus | embryonic stage | germline clone,dorsal appendage,imaginal disc,follicle cell,embryonic/larval lymph gland,imaginal ring,salivary gland common duct primordium,photoreceptor cell R7,trichogen cell" DRSC07666 E 0.285944396 0.09011778 1.721196849 0.002320368 -0.211837567 -0.153926941 FBgn0011267 sbn scatterbrained http://flybase.net/reports/FBgn0011267.html gene 16-Dec-15 2015_12 "developmental rate defective,non-rescuable maternal effect" FBgn0014261 l(2)N7-8 lethal (2) N7-8 http://flybase.net/reports/FBgn0014261.html gene N7-8 16-Dec-15 2015_12 "lethal,recessive" FBgn0263873 sick sickie http://flybase.net/reports/FBgn0263873.html "FBgn0260966, FBgn0085372, FBgn0032830, FBgn0053316, FBgn0032828, FBgn0032832, FBgn0032826, FBgn0032831, FBgn0032825" protein_coding_gene 0005524=ATP binding "0007409=axonogenesis, 0007015=actin filament organization, 0050829=defense response to Gram-negative bacterium" "CG13960, CG33316, sick, CG42589, CG13961, Dm_2L:104545, CG13964, CG43720, sickie, CG13958, CG13959, CG10662, CG34343" "IPR003593=AAA+ ATPase domain, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001715=Calponin homology domain" CG43720 16-Dec-15 2015_12 ENSDARG00000005476(nav3) WBGene00006788(unc-53) "ENSXETG00000014194(),ENSXETG00000017089(NAV1)" "ENSMUSG00000020181(Nav3),ENSMUSG00000009418(Nav1)" "ENSG00000166833(NAV2),ENSG00000067798(NAV3),ENSG00000134369(NAV1)" FBgn0020762 Atet ABC transporter expressed in trachea http://flybase.net/reports/FBgn0020762.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005215=transporter activity, 0005524=ATP binding" 0022008=neurogenesis 0043190=ATP-binding cassette (ABC) transporter complex CG2969 "IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR003593=AAA+ ATPase domain, IPR013525=ABC-2 type transporter, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG2969 16-Dec-15 2015_12 ENSDARG00000061047(LOC564842) ENSXETG00000021581(ABCG4) "ENSMUSG00000024030(Abcg1),ENSMUSG00000032131(Abcg4)" "ENSG00000160179(ABCG1),ENSG00000172350(ABCG4)" "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC00263 I 1.661073175 1.032050378 0.49406365 0.195466716 -0.058499371 0.925317355 FBgn0051961 CG31961 http://flybase.net/reports/FBgn0051961.html "FBgn0031587, FBgn0046772" protein_coding_gene "0007021=tubulin complex assembly, 0000902=cell morphogenesis, 0007023=post-chaperonin tubulin folding pathway, 0022008=neurogenesis" "CG3381, BcDNA:LD34582" "IPR006599=CARP motif, IPR027684=Tubulin-specific chaperone C, IPR016098=Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal, IPR017901=C-CAP/cofactor C-like domain, IPR012945=Tubulin binding cofactor C-like domain" CG31961 16-Dec-15 2015_12 ENSDARG00000022918(tbccl) WBGene00044609(Y71H2AM.24) ENSXETG00000000215(TBCC) ENSMUSG00000036430(Tbcc) ENSG00000124659(TBCC) "viable,fertile,lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,tormogen cell" FBgn0085412 CG34383 http://flybase.net/reports/FBgn0085412.html "FBgn0038177, FBgn0038176, FBgn0038178" protein_coding_gene "CG9322, CG14365, Dm_3R:52023, CG14366" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG34383 16-Dec-15 2015_12 "ENSG00000143850(PLEKHA6),ENSG00000052126(PLEKHA5),ENSG00000166689(PLEKHA7)" FBgn0038045 NANS N-acetylneuraminic acid synthase http://flybase.net/reports/FBgn0038045.html protein_coding_gene 0047444=N-acylneuraminate-9-phosphate synthase activity "0070085=glycosylation, 0016051=carbohydrate biosynthetic process" "Sialic acid phosphate synthase, Neu5Ac, DmSAS, Sas, sas, N-acetylneuraminic acid phosphate synthase, Neu5Ac synthase, CG5232, sialic acid synthase, SAS" "IPR013132=N-acetylneuraminic acid synthase, N-terminal, IPR006190=Antifreeze-like/N-acetylneuraminic acid synthase C-terminal, IPR013785=Aldolase-type TIM barrel, IPR013974=SAF domain" CG5232 16-Dec-15 2015_12 "ENSDARG00000045620(zgc:77126),ENSDARG00000036009" ENSXETG00000006558(NANS) ENSMUSG00000028334(Nans) ENSG00000095380(NANS) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0031598 Vps53 Vacuolar protein sorting 53 http://flybase.net/reports/FBgn0031598.html protein_coding_gene 0005515=protein binding 0032456=endocytic recycling 0005794=Golgi apparatus CG3338 "IPR007234=Vps53-like, N-terminal" CG3338 16-Dec-15 2015_12 ENSDARG00000069324(vps53) YJL029C(VPS53) WBGene00011502(vps-53) ENSXETG00000022432() ENSMUSG00000017288(Vps53) ENSG00000141252(VPS53) viable FBgn0086348 se sepia http://flybase.net/reports/FBgn0086348.html "FBgn0003351, FBgn0035905" protein_coding_gene "0042803=protein homodimerization activity, 0004364=glutathione transferase activity, 0016782=transferase activity, transferring sulfur-containing groups, 0045174=glutathione dehydrogenase (ascorbate) activity, 0004734=pyrimidodiazepine synthase activity" "0006726=eye pigment biosynthetic process, 0006749=glutathione metabolic process, 0006728=pteridine biosynthetic process" 0005737=cytoplasm "dmgsto1, GSTO1, sepia, GSTO4, CG6781, cg6781" "IPR010987=Glutathione S-transferase, C-terminal-like, IPR004045=Glutathione S-transferase, N-terminal, IPR005442=Glutathione S-transferase, omega-class, IPR012336=Thioredoxin-like fold" CG6781 16-Dec-15 2015_12 "ENSDARG00000022183(zgc:92254),ENSDARG00000033285(zgc:101897)" "WBGene00019636(gsto-3),WBGene00001792(gst-44),WBGene00016204(gsto-1)" "ENSXETG00000026602(TEgg023j21.1),ENSXETG00000026601(BC087558.1),ENSXETG00000016907()" "ENSMUSG00000025068(Gsto1),ENSMUSG00000025069(Gsto2)" "ENSG00000148834(GSTO1),ENSG00000065621(GSTO2)" FBgn0037843 CG4511 http://flybase.net/reports/FBgn0037843.html protein_coding_gene 0005524=ATP binding "IPR012336=Thioredoxin-like fold, IPR024253=Phosducin, thioredoxin-like domain" CG4511 16-Dec-15 2015_12 ENSDARG00000069853(txndc9) YDR183W(PLP1) WBGene00006515(tag-170) ENSXETG00000019374() ENSMUSG00000058407(Txndc9) ENSG00000115514(TXNDC9) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0262514 VhaPPA1-2 Vacuolar H+ ATPase PPA1 subunit 2 http://flybase.net/reports/FBgn0262514.html "FBgn0028661, FBgn0038276" protein_coding_gene "0015078=hydrogen ion transmembrane transporter activity, 0046961=proton-transporting ATPase activity, rotational mechanism" 0015991=ATP hydrolysis coupled proton transport "0033176=proton-transporting V-type ATPase complex, 0000220=vacuolar proton-transporting V-type ATPase, V0 domain" "CG7026, unnamed, VhaPPA1-2, Vacuolar H[+] ATPase subunit PPA1-2, vhaPPA1-2" "IPR002379=V-ATPase proteolipid subunit C-like domain, IPR000245=V-ATPase proteolipid subunit" CG7026 16-Dec-15 2015_12 ENSDARG00000031681(atp6v0b) YHR026W(PPA1) FBgn0032514 CG9302 http://flybase.net/reports/FBgn0032514.html FBgn0061636 protein_coding_gene 0003756=protein disulfide isomerase activity 0045454=cell redox homeostasis 0012505=endomembrane system anon-WO0118547.80 "IPR012336=Thioredoxin-like fold, IPR017937=Thioredoxin, conserved site, IPR013766=Thioredoxin domain" CG9302 16-Dec-15 2015_12 ENSDARG00000069242(pdia5) YIL005W(EPS1) WBGene00001045(dnj-27) ENSMUSG00000022844(Pdia5) ENSG00000065485(PDIA5) "lethal,partially lethal - majority die,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0032969 CG2528 http://flybase.net/reports/FBgn0032969.html protein_coding_gene "0070008=serine-type exopeptidase activity, 0004252=serine-type endopeptidase activity, 0004177=aminopeptidase activity" 0006508=proteolysis lincRNA.224 "IPR002470=Peptidase S9A, prolyl oligopeptidase, IPR002471=Peptidase S9, serine active site, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR029058=Alpha/Beta hydrolase fold, IPR023302=Peptidase S9A, N-terminal domain" CG2528 16-Dec-15 2015_12 ENSDARG00000057151(prep) WBGene00001058(dpf-5) ENSXETG00000013305(prep) ENSMUSG00000019849(Prep) ENSG00000085377(PREP) viable FBgn0261547 Exn Ephexin http://flybase.net/reports/FBgn0261547.html "FBgn0027593, FBgn0036683" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity "0007480=imaginal disc-derived leg morphogenesis, 0046928=regulation of neurotransmitter secretion, 0035011=melanotic encapsulation of foreign target, 0035025=positive regulation of Rho protein signal transduction" "0042734=presynaptic membrane, 0031594=neuromuscular junction" "CG42665, ephexin, BcDNA:GH03693, exn, CG3799, CG14060" "IPR001452=SH3 domain, IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain" CG42665 16-Dec-15 2015_12 "ENSDARG00000059742,ENSDARG00000061844" WBGene00019487(tag-218) "ENSMUSG00000052921(Arhgef15),ENSMUSG00000028919(Arhgef19),ENSMUSG00000026259(Ngef)" "ENSG00000114790(ARHGEF26),ENSG00000130762(ARHGEF16)" FBgn0000228 Bsg25D Blastoderm-specific gene 25D http://flybase.net/reports/FBgn0000228.html protein_coding_gene "bsq25D, brg25D, CG14025, bsg25D" CG14025 16-Dec-15 2015_12 ENSDARG00000060298(nin) ENSXETG00000016467(NIN) "ENSMUSG00000068115(Ninl),ENSMUSG00000021068(Nin)" "ENSG00000101004(NINL),ENSG00000100503(NIN)" " embryonic stage | <=8 hr , embryonic stage | blastoderm " viable FBgn0259482 Mob3 http://flybase.net/reports/FBgn0259482.html "FBgn0032203, FBgn0083173" protein_coding_gene 0019901=protein kinase binding "DMob3, dmob3, Mob3, Dmob3, CG4946" IPR005301=MOB kinase activator family CG4946 16-Dec-15 2015_12 "ENSDARG00000019113(mobkl2a),ENSDARG00000043705(mobkl2c)" YIL106W(MOB1) WBGene00020447(T12B3.4) "ENSXETG00000013664(mobkl2a),ENSXETG00000016355(MOBKL2C)" "ENSMUSG00000073910(Mobkl2b),ENSMUSG00000003348(Mobkl2a),ENSMUSG00000028709(Mobkl2c)" "ENSG00000120162(MOBKL2B),ENSG00000172081(MOBKL2A),ENSG00000142961(MOBKL2C)" FBgn0037328 RpL35A Ribosomal protein L35A http://flybase.net/reports/FBgn0037328.html FBgn0026272 protein_coding_gene 0003735=structural constituent of ribosome "0040018=positive regulation of multicellular organism growth, 0006412=translation, 0090277=positive regulation of peptide hormone secretion" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "L35a, anon-EST:Posey39, Rpl35A, CG2099, Rp L35A" "IPR009000=Translation protein, beta-barrel domain, IPR001780=Ribosomal protein L35A, IPR018266=Ribosomal protein L35Ae, conserved site" CG2099 16-Dec-15 2015_12 ENSDARG00000040676 "YOR234C(RPL33B),YPL143W(RPL33A)" WBGene00004447(rpl-33) ENSXETG00000027871(rpl35) "ENSMUSG00000070519(Rpl35a-ps6),ENSMUSG00000060636(Rpl35a),ENSMUSG00000067558(Rpl35a-ps5),ENSMUSG00000067575(Rpl35a-ps3),ENSMUSG00000068674(Gm10247),ENSMUSG00000068324(Gm10237),ENSMUSG00000062279(Gm16514)" ENSG00000182899(RPL35A) lethal DRSC12302 IEK -1.614712965 -2.314268716 0.308625431 -5.26450209 1.467252014 3.8624467 FBgn0050431 CG30431 http://flybase.net/reports/FBgn0050431.html "FBgn0033070, FBgn0033071" protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0003677=DNA binding" 0005634=nucleus "CG8341, CG8324" "IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG30431 16-Dec-15 2015_12 "ENSXETG00000025953(),ENSXETG00000025954(),ENSXETG00000017336(),ENSXETG00000025955(TNeu074i11.1),ENSXETG00000027339(),ENSXETG00000009586(),ENSXETG00000025952(),ENSXETG00000012399(),ENSXETG00000017351(),ENSXETG00000006640(),ENSXETG00000024246(),ENSXETG00000027532(),ENSXETG00000015004(),ENSXETG00000002252(),ENSXETG00000020813(),ENSXETG00000021213(),ENSXETG00000012440(),ENSXETG00000025956(),ENSXETG00000017373(),ENSXETG00000027216(),ENSXETG00000004686(),ENSXETG00000020496(),ENSXETG00000027484(),ENSXETG00000027329(),ENSXETG00000002307(),ENSXETG00000002690(),ENSXETG00000013033(),ENSXETG00000000727(),ENSXETG00000020960(),ENSXETG00000007072(),ENSXETG00000008144(),ENSXETG00000020215(),ENSXETG00000016062(),ENSXETG00000027163(TNeu041e20.1)" FBgn0020767 Spred Sprouty-related protein with EVH-1 domain http://flybase.net/reports/FBgn0020767.html FBgn0033964 protein_coding_gene "0007275=multicellular organismal development, 0009966=regulation of signal transduction" "0005829=cytosol, 0016020=membrane" "spred, dSPRED, AE33, CG10155, Dm AE33" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR007875=Sprouty, IPR000697=WH1/EVH1 domain" CG10155 16-Dec-15 2015_12 "ENSDARG00000041449(spred1),ENSDARG00000008372(spred2),ENSDARG00000052435(LOC558432),ENSDARG00000040358(si:ch211-255l12.2)" "ENSXETG00000018057(spred1),ENSXETG00000014000(spred2),ENSXETG00000002819(SPRED3)" "ENSMUSG00000027351(Spred1),ENSMUSG00000045671(Spred2),ENSMUSG00000037239(Spred3)" "ENSG00000166068(SPRED1),ENSG00000198369(SPRED2),ENSG00000188766(SPRED3)" viable DRSC05976 I 1.537855042 1.289213427 1.019361063 0.0123239 -0.05308179 0.182783603 FBgn0262737 mub mushroom-body expressed http://flybase.net/reports/FBgn0262737.html "FBgn0014362, FBgn0010834, FBgn0011394, FBgn0011408, FBgn0046394, FBgn0046395, FBgn0046396, FBgn0046397, FBgn0086548" protein_coding_gene 0017130=poly(C) RNA binding "0040040=thermosensory behavior, 0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "poly (rC) binding protein, Mushroom-body expressed, mushroom bodies, mushroom body expressed, l(3)04093, l(3)j8B3, anon-WO0172774.33, MUB, Mub, anon-WO0172774.36, MRE17, mRNA-like ncRNA in embryogenesis 17, anon-WO0172774.37, CG7437, anon-WO0172774.35, l(3)j6B10" "IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG7437 16-Dec-15 2015_12 "ENSDARG00000054378(pcbp3),ENSDARG00000013184(pcbp2),ENSDARG00000057141(zgc:110045),ENSDARG00000024276(LOC100331052)" YBR233W(PBP2) "ENSXETG00000012658(TEgg050e10.1),ENSXETG00000010491(pcbp3),ENSXETG00000011483(PCBP3)" "ENSMUSG00000001120(Pcbp3),ENSMUSG00000056851(Pcbp2),ENSMUSG00000051695(Pcbp1),ENSMUSG00000023495(Pcbp4)" "ENSG00000183570(PCBP3),ENSG00000197111(PCBP2),ENSG00000169564(PCBP1)" FBgn0261573 CoRest CoRest http://flybase.net/reports/FBgn0261573.html "FBpp0074493, FBtr0074726, FBpp0074495, FBgn0052534, FBgn0053525, FBgn0031025, FBgn0046809, FBgn0052535, FBgn0063163, FBtr0074722, FBpp0074491, FBtr0074723, FBpp0074492, FBtr0074724" protein_coding_gene "0003682=chromatin binding, 0003677=DNA binding, 0005515=protein binding, 0003714=transcription corepressor activity" "0061086=negative regulation of histone H3-K27 methylation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045747=positive regulation of Notch signaling pathway, 2000619=negative regulation of histone H4-K16 acetylation, 0007221=positive regulation of transcription of Notch receptor target, 0045892=negative regulation of transcription, DNA-templated" "0017053=transcriptional repressor complex, 0005634=nucleus" "CG3878, dCoREST, CoRESTG, CoREST, CG32535, i169, CG33525, CG42687, BcDNA:GH01486, BcDNA:LD11215, CG32534" "IPR017884=SANT domain, IPR000949=ELM2 domain, IPR009057=Homeodomain-like, IPR001005=SANT/Myb domain" CG42687 16-Dec-15 2015_12 "ENSDARG00000008278(rcor2),ENSDARG00000004502(LOC563808),ENSDARG00000031434(rcor1)" "WBGene00022278(Y74C9A.4),WBGene00005006(spr-1)" "ENSXETG00000005989(RCOR3),ENSXETG00000012743(rcor1),ENSXETG00000002710(rcor2)" "ENSMUSG00000024968(Rcor2),ENSMUSG00000037896(Rcor1),ENSMUSG00000037395(Rcor3)" "ENSG00000167771(RCOR2),ENSG00000117625(RCOR3),ENSG00000089902(RCOR1)" DRSC22305 IEK 2.819467377 -3.133707857 1.301265246 -1.975353383 1.518618668 0.882145134 FBgn0001285 Jon44E Jonah 44E http://flybase.net/reports/FBgn0001285.html FBgn0033319 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "Jon43E, Jonah 43E, CG8579, SP100" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG8579 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0033350 CG8237 http://flybase.net/reports/FBgn0033350.html protein_coding_gene IPR010432=RDD CG8237 16-Dec-15 2015_12 "ENSDARG00000004308(fam8a1),ENSDARG00000017111(LOC563822)" WBGene00018593(F48B9.8) ENSXETG00000014196(FAM8A1) ENSMUSG00000069237(C78339) ENSG00000137414(FAM8A1) viable FBgn0039994 conu conundrum http://flybase.net/reports/FBgn0039994.html "FBan0017082, FBgn0047230, FBgn0058286" protein_coding_gene "0005515=protein binding, 0005096=GTPase activator activity" "0008284=positive regulation of cell proliferation, 0034260=negative regulation of GTPase activity, 0043547=positive regulation of GTPase activity" 0045179=apical cortex "CG40286, CG17082, BcDNA:LD04957" "IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG17082 16-Dec-15 2015_12 ENSDARG00000005872(zgc:101668) "ENSXETG00000014909(ARHGAP18),ENSXETG00000004957(ARHGAP28),ENSXETG00000012135(C20orf95)" "ENSMUSG00000039031(Arhgap18),ENSMUSG00000024043(Arhgap28),ENSMUSG00000074625(Arhgap40)" "ENSG00000146376(ARHGAP18),ENSG00000088756(ARHGAP28)" "viable,fertile,cell shape defective,neoplasia,increased cell size" "wing disc,eye" FBgn0034817 Art7 Arginine methyltransferase 7 http://flybase.net/reports/FBgn0034817.html protein_coding_gene 0016274=protein-arginine N-methyltransferase activity "0019919=peptidyl-arginine methylation, to asymmetrical-dimethyl arginine" "DART8, CG9882, dart7, DART7" "IPR025799=Protein arginine N-methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR014644=Protein arginine N-methyltransferase PRMT7" CG9882 16-Dec-15 2015_12 ENSDARG00000051902(prmt7) WBGene00012298(prmt-2) ENSXETG00000006676(PRMT7) ENSMUSG00000060098(Prmt7) ENSG00000132600(PRMT7) "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0036492 Best3 Bestrophin 3 http://flybase.net/reports/FBgn0036492.html protein_coding_gene 0005254=chloride channel activity 0006821=chloride transport 0005887=integral component of plasma membrane "dbest3, dBest3, CG12327" "IPR021134=Bestrophin/UPF0187, IPR000615=Bestrophin" CG12327 16-Dec-15 2015_12 "WBGene00022797(ZK688.2),WBGene00007203(B0564.3),WBGene00011868(T20G5.4),WBGene00007204(B0564.4),WBGene00007808(C29F4.2),WBGene00007404(C07A9.8),WBGene00013921(ZC518.1),WBGene00011258(R13.3)" "ENSXETG00000013592(BEST4),ENSXETG00000025368(BC061379.1),ENSXETG00000001407(BEST3),ENSXETG00000006740(BEST1)" "ENSMUSG00000052819(Best2),ENSMUSG00000020169(Best3),ENSMUSG00000037418(Best1)" "ENSG00000039987(BEST2),ENSG00000127325(BEST3),ENSG00000142959(BEST4),ENSG00000167995(BEST1)" viable FBgn0032209 Hand Hand http://flybase.net/reports/FBgn0032209.html protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0043066=negative regulation of apoptotic process, 0007508=larval heart development, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0035050=embryonic heart tube development, 0030097=hemopoiesis, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis" 0005634=nucleus "dHAND, CG18144, bHLHa28, Dhand, hand, HAND, dHand, hand-C" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG18144 16-Dec-15 2015_12 ENSDARG00000008305(hand2) "ENSXETG00000016908(HAND2),ENSXETG00000008479(hand1)" "ENSMUSG00000038193(Hand2),ENSMUSG00000037335(Hand1)" "ENSG00000164107(HAND2),ENSG00000113196(HAND1)" "neuroanatomy defective,lethal - all die before end of larval stage,some die during third instar larval stage,lethal,small body,locomotor rhythm defective,increased cell death,partially lethal - majority die,recessive,fertile,short lived,some die during first instar larval stage,flight defective,locomotor behavior defective,some die during immature adult stage,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,cardioblast,embryonic pericardial cell,lymph gland primordium,alary cell,lymph gland derived hemocyte,embryonic/larval heart,embryonic/larval pericardial cell,embryonic/larval lymph gland,adult peritrophic membrane,adult dorsal vessel,adult midgut,crop" FBgn0001206 Hmr Hybrid male rescue http://flybase.net/reports/FBgn0001206.html FBgn0027511 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005515=protein binding" "0010528=regulation of transposition, 0000723=telomere maintenance, 0010529=negative regulation of transposition, 0000070=mitotic sister chromatid segregation" "0005700=polytene chromosome, 0000792=heterochromatin, 0000775=chromosome, centromeric region, 0005730=nucleolus, 0005701=polytene chromosome chromocenter, 0035012=polytene chromosome, telomeric region" "BcDNA:LD22117, CG1619, Hmr[[mel]], hmr, hybrid male rescue, Hmr-mel, HMR" "IPR016641=Nascent polypeptide-associated complex subunit alpha, IPR006578=MADF domain" CG1619 16-Dec-15 2015_12 "female sterile,partially,recessive" "egg,ovariole,egg chamber,dorsal appendage" FBgn0032896 CG14400 http://flybase.net/reports/FBgn0032896.html protein_coding_gene CG14400 16-Dec-15 2015_12 viable DRSC02384 I 2.401640782 0.15045359 0.312504301 0.331317489 -0.138508357 0.53846124 FBgn0022039 l(2)k08407 lethal (2) k08407 http://flybase.net/reports/FBgn0022039.html gene 16-Dec-15 2015_12 "visible,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing vein" FBgn0002422 l(3)F13 lethal (3) F13 http://flybase.net/reports/FBgn0002422.html gene l(3)13 16-Dec-15 2015_12 "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0034131 CG15712 http://flybase.net/reports/FBgn0034131.html protein_coding_gene IPR010629=Insect allergen-related CG15712 16-Dec-15 2015_12 viable FBgn0032262 CG7384 http://flybase.net/reports/FBgn0032262.html protein_coding_gene IPR005240=Protein of unknown function DUF389 CG7384 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053051 CG33051 http://flybase.net/reports/FBgn0053051.html FBgn0036719 protein_coding_gene "0022008=neurogenesis, 0006359=regulation of transcription from RNA polymerase III promoter" CG3882 "IPR024661=DNA-directed RNA polymerase III, subunit Rpc31" CG33051 16-Dec-15 2015_12 "ENSDARG00000012044(zgc:101594),ENSDARG00000013734(zgc:101891),ENSDARG00000024687(LOC100000978)" "ENSXETG00000019625(POLR3G),ENSXETG00000011053(POLR3GL)" "ENSMUSG00000035834(Polr3g),ENSMUSG00000028104(Polr3gl)" "ENSG00000121851(POLR3GL),ENSG00000113356(POLR3G)" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0039858 CycG Cyclin G http://flybase.net/reports/FBgn0039858.html "FBgn0025961, FBgn0026001" protein_coding_gene 0016538=cyclin-dependent protein serine/threonine kinase regulator activity "0006302=double-strand break repair, 0000711=meiotic DNA repair synthesis, 0060429=epithelium development, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0007143=female meiotic division" 0005700=polytene chromosome "i205, anon-EST:Liang-1.25, clone 2.24, chr3R:27424276..27424475, dCycG, CG11525, anon-EST:Liang-2.24, cycG, CG 11525, i261, clone 1.25, cyclin G1" "IPR006671=Cyclin, N-terminal, IPR013763=Cyclin-like" CG11525 16-Dec-15 2015_12 "ENSDARG00000017602(ccng2),ENSDARG00000028209(ccng1)" "ENSMUSG00000029385(Ccng2),ENSMUSG00000020326(Ccng1)" "ENSG00000138764(CCNG2),ENSG00000113328(CCNG1)" "lethal,developmental rate defective,increased cell size,partially lethal - majority die,male limited,partially lethal - majority live,female limited,viable,decreased cell size,mitotic cell cycle defective,somatic clone,female sterile,fertile" "wing,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,male genitalia,female limited,ommatidium,anterior dorsal histoblast nest abdominal 4,posterior dorsal histoblast nest abdominal 4,anterior dorsal histoblast nest abdominal 5,posterior dorsal histoblast nest abdominal 5,anterior dorsal histoblast nest abdominal 6,posterior dorsal histoblast nest abdominal 6,wing disc,posterior compartment,somatic clone,dorsal appendage,maternal effect,germline clone,karyosome" DRSC14324 I 0.852304076 -1.525231705 -0.742036846 -0.187639725 0.278644861 -0.639233176 FBgn0028703 Nhe3 Na+/H+ hydrogen exchanger 3 http://flybase.net/reports/FBgn0028703.html protein_coding_gene 0015385=sodium:proton antiporter activity "0006814=sodium ion transport, 0006885=regulation of pH, 0055085=transmembrane transport" "0016021=integral component of membrane, 0048471=perinuclear region of cytoplasm" "Nhe3, CG11328, nhe3, NHE3, DmNHE3" "IPR018422=Cation/H+ exchanger, CPA1 family, IPR002090=Na+/H+ exchanger, isoform 6 (NHE6), IPR004709=Na+/H+ exchanger, IPR006153=Cation/H+ exchanger" CG11328 16-Dec-15 2015_12 ENSDARG00000009209(slc9a6a) WBGene00003733(nhx-5) "ENSXETG00000019761(SLC9A6),ENSXETG00000004133(),ENSXETG00000001625(SLC9A9)" "ENSMUSG00000037341(Slc9a7),ENSMUSG00000060681(Slc9a6),ENSMUSG00000031129(Slc9a9)" "ENSG00000198689(SLC9A6),ENSG00000065923(SLC9A7),ENSG00000181804(SLC9A9)" viable FBgn0039307 CR13656 http://flybase.net/reports/FBgn0039307.html pseudogene_attribute CG13656 CR13656 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0036199 Bmcp Bmcp http://flybase.net/reports/FBgn0036199.html protein_coding_gene 0022857=transmembrane transporter activity "0007605=sensory perception of sound, 0006839=mitochondrial transport, 0019222=regulation of metabolic process, 0055085=transmembrane transport" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane" "DmBMCP, dmUCP5, bmcp, CG7314, ucp5, DmUCP5, UCP5, Ucp5" "IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain" CG7314 16-Dec-15 2015_12 ENSDARG00000026680(slc25a14) ENSXETG00000014657(slc25a30) "ENSMUSG00000022003(Slc25a30),ENSMUSG00000031105(Slc25a14)" "ENSG00000174032(SLC25A30),ENSG00000102078(SLC25A14)" "stress response defective,viable,auditory perception defective,neurophysiology defective" FBgn0024947 NTPase NTPase http://flybase.net/reports/FBgn0024947.html protein_coding_gene "0017110=nucleoside-diphosphatase activity, 0045134=uridine-diphosphatase activity, 0017111=nucleoside-triphosphatase activity, 0004382=guanosine-diphosphatase activity" 0005737=cytoplasm "CD39-like NTPase, CG3059, NTPDase6, dmNTPase" IPR000407=Nucleoside phosphatase GDA1/CD39 CG3059 16-Dec-15 2015_12 "ENSDARG00000053481(LOC556849),ENSDARG00000070443,ENSDARG00000008757(entpd6)" YEL042W(GDA1) WBGene00010697(uda-1) ENSXETG00000012776(ENTPD6) "ENSMUSG00000021236(Entpd5),ENSMUSG00000033068(Entpd6)" "ENSG00000187097(ENTPD5),ENSG00000197586(ENTPD6)" viable DRSC26233 K 0.045008898 -0.514548332 0.419207756 -0.249423221 -1.292641967 -1.583626239 FBgn0020909 Rtc1 Rtc1 http://flybase.net/reports/FBgn0020909.html protein_coding_gene 0003963=RNA-3'-phosphate cyclase activity "0006396=RNA processing, 0009267=cellular response to starvation, 0042254=ribosome biogenesis" "0005634=nucleus, 0005730=nucleolus" CG11130 "IPR013791=RNA 3'-terminal phosphate cyclase, insert domain, IPR020719=RNA 3'-terminal phosphate cyclase-like, conserved site, IPR023797=RNA 3'-terminal phosphate cyclase domain, IPR016443=RNA 3'-terminal phosphate cyclase type 2, IPR013792=RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta, IPR000228=RNA 3'-terminal phosphate cyclase" CG11130 16-Dec-15 2015_12 ENSDARG00000038312(rcl1) YOL010W(RCL1) WBGene00022852(ZK1127.5) ENSXETG00000000592(RCL1) ENSMUSG00000024785(Rcl1) ENSG00000120158(RCL1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC20285 E -1.011133935 -0.196341902 2.129391108 0.702359788 0.930255036 0.315352417 FBgn0283479 Alp1 Alkaline phosphatase 1 http://flybase.net/reports/FBgn0283479.html "FBgn0000106, FBgn0037083" protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "Aph-1, larval Alkaline phosphatase, Aph, pupal Alkaline phosphatase, Alkaline phosphatase-1, APH, p-Aph, l-Aph, CG5656, unnamed, Alkaline phosphatase" "IPR017850=Alkaline-phosphatase-like, core domain, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase" CG5656 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" FBgn0026148 CG12253 http://flybase.net/reports/FBgn0026148.html FBgn0032326 protein_coding_gene "PIF-like gene 1, LD08487, BEST:LD08487, DPLG1" IPR027806=Harbinger transposase-derived nuclease domain CG12253 16-Dec-15 2015_12 "ENSDARG00000028815(zgc:162945),ENSDARG00000070829,ENSDARG00000023991,ENSDARG00000068583,ENSDARG00000069068,ENSDARG00000042844,ENSDARG00000038514,ENSDARG00000036038(harbi1)" "ENSXETG00000028037(),ENSXETG00000002193(),ENSXETG00000020552(),ENSXETG00000009204(),ENSXETG00000010792(),ENSXETG00000005639(),ENSXETG00000008310(),ENSXETG00000019954(),ENSXETG00000023180(),ENSXETG00000002188(),ENSXETG00000000133(),ENSXETG00000001981(HARBI1),ENSXETG00000022776(),ENSXETG00000025431(),ENSXETG00000011195(),ENSXETG00000026623(),ENSXETG00000001100()" ENSMUSG00000027243(Harbi1) ENSG00000180423(HARBI1) viable FBgn0034057 CG8314 http://flybase.net/reports/FBgn0034057.html FBgn0061525 protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" 0018345=protein palmitoylation 0005794=Golgi apparatus anon-WO0118547.93 "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG8314 16-Dec-15 2015_12 "ENSDARG00000058830,ENSDARG00000010981(zdhhc3),ENSDARG00000019484(zgc:92305)" YLR246W(ERF2) WBGene00018009(F33D11.12) "ENSXETG00000020145(zdhhc3),ENSXETG00000025991(ZDHHC7)" "ENSMUSG00000025786(Zdhhc3),ENSMUSG00000031823(Zdhhc7)" "ENSG00000163812(ZDHHC3),ENSG00000153786(ZDHHC7)" viable FBgn0024957 Irp-1B Iron regulatory protein 1B http://flybase.net/reports/FBgn0024957.html protein_coding_gene "0003729=mRNA binding, 0030350=iron-responsive element binding, 0005506=iron ion binding, 0003994=aconitate hydratase activity" "0006447=regulation of translational initiation by iron, 0008152=metabolic process" "C-Acon, cytosolic aconitase, cACON, c-aconitase, IRP-1, irp1B, iron regulatory protein 1B, Iron regulatory protein, dIRP, cytoplasmic aconitase, IRP-1B, IRF, iron regulatory factor, cAcon, irp-1B, IRP1, IRP, 144037_at, CG6342" "IPR015937=Aconitase/isopropylmalate dehydratase, IPR018136=Aconitase family, 4Fe-4S cluster binding site, IPR015932=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR006249=Aconitate/Iron-responsive element-binding protein 2, IPR001030=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR015931=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR000573=Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR015934=Aconitase/2-methylisocitrate dehydratase, IPR015928=Aconitase/3-isopropylmalate dehydratase, swivel" CG6342 16-Dec-15 2015_12 ENSDARG00000021466 WBGene00000040(aco-1) ENSXETG00000009184(ACO1) ENSMUSG00000028405(Aco1) ENSG00000122729(ACO1) embryonic stage

ubiquitous viable DRSC16720 K 0.090566824 0.300317442 -0.153741897 1.119953391 -0.286727145 -1.604563446 FBgn0030766 mthl1 methuselah-like 1 http://flybase.net/reports/FBgn0030766.html "FBgn0046548, FBgn0046549" protein_coding_gene 0004930=G-protein coupled receptor activity "0007509=mesoderm migration involved in gastrulation, 0007186=G-protein coupled receptor signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0042594=response to starvation, 0007472=wing disc morphogenesis, 0007369=gastrulation, 0070252=actin-mediated cell contraction, 0008340=determination of adult lifespan" 0016021=integral component of membrane "mth-like 1, anon-WO0170980.23, anon-WO0170980.22, Mth-1, mesoderm-invagination signal transducer, mist, Mth-like 1, CG4521" "IPR000832=GPCR, family 2, secretin-like, IPR023311=Methuselah ectodomain, domain 2, IPR017981=GPCR, family 2-like" CG4521 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" "viable,fertile" wing disc FBgn0035772 Sh3ë_ Sh3ë_ http://flybase.net/reports/FBgn0035772.html protein_coding_gene "SH3beta, CG8582, LD12912, Sh3beta" "IPR006993=SH3-binding, glutamic acid-rich protein, IPR012336=Thioredoxin-like fold" CG8582 16-Dec-15 2015_12 "ENSDARG00000070035,ENSDARG00000021633(zgc:100896),ENSDARG00000058302(zgc:64130),ENSDARG00000036878(zgc:91852)" WBGene00013666(Y105E8A.1) ENSXETG00000012330() "ENSMUSG00000040666(Sh3bgr),ENSMUSG00000031246(Sh3bgrl)" ENSG00000185437(SH3BGR) "lethal,viable" adult heart FBgn0038302 CG4210 http://flybase.net/reports/FBgn0038302.html "FBgn0062846, FBgn0064777" protein_coding_gene 0008080=N-acetyltransferase activity "FBgn 38302, BcDNA:SD13446, BcDNA:SD26038" "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase" CG4210 16-Dec-15 2015_12 "ENSDARG00000035215(zgc:92773),ENSDARG00000036430(sat2),ENSDARG00000032272(sat1),ENSDARG00000035652(zgc:114142)" WBGene00008408(D2023.4) ENSXETG00000022884(SAT2) "ENSMUSG00000069835(Sat2),ENSMUSG00000025283(Sat1)" ENSG00000141504(SAT2) viable FBgn0034176 ste24a prenyl protease type I http://flybase.net/reports/FBgn0034176.html protein_coding_gene 0004222=metalloendopeptidase activity 0071586=CAAX-box protein processing 0016020=membrane "Dmel\Ste24a, CG9000, Dmel\Ste24, ste24a" "IPR001915=Peptidase M48, IPR027057=CAAX prenyl protease 1" CG9000 16-Dec-15 2015_12 ENSDARG00000044090(zmpste24) YJR117W(STE24) WBGene00001405(fce-1) ENSXETG00000026791(zmpste24) ENSMUSG00000043207(Zmpste24) ENSG00000084073(ZMPSTE24) "viable,fertile" DRSC26491 K 0.737591429 0.607772447 0.375596872 -0.035028988 0.107675358 1.882966932 FBgn0026361 5-Sep Septin 5 http://flybase.net/reports/FBgn0026361.html FBgn0033242 protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0000281=mitotic cytokinesis, 0051726=regulation of cell cycle, 0007444=imaginal disc development" "0005940=septin ring, 0005875=microtubule associated complex" "CG2916, septin, septin 5, Sep, sep5, Sep5, Septin-5, Septin 5" "IPR030379=Septin-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR016491=Septin" CG2916 16-Dec-15 2015_12 "ENSDARG00000010721(sept6),ENSDARG00000011164(sept10),ENSDARG00000032606(sept8a),ENSDARG00000014233(sept8b)" WBGene00006795(unc-61) "ENSXETG00000007443(SEPT6),ENSXETG00000006404(sept8),ENSXETG00000013836(sept10)" "ENSMUSG00000058013(Sept11),ENSMUSG00000050379(Sept6),ENSMUSG00000018398(Sept8),ENSMUSG00000019917(Sept10)" "ENSG00000138758(SEPT11),ENSG00000125354(SEPT6),ENSG00000164402(SEPT8),ENSG00000186522(SEPT10)" "viable,fertile" DRSC29954 K 0.359303028 0.312490591 -0.024393112 0.274095324 -0.033047005 1.551718985 FBgn0004463 RpIII128 RNA polymerase III 128kD subunit http://flybase.net/reports/FBgn0004463.html "FBtr0087977, FBpp0087085" protein_coding_gene "0003677=DNA binding, 0003899=DNA-directed RNA polymerase activity, 0032549=ribonucleoside binding" 0006383=transcription from RNA polymerase III promoter "0005634=nucleus, 0005666=DNA-directed RNA polymerase III complex" "RP128, DmRP128, RNA polymerase IIIb, RNA polymerase III, CG8344" "IPR007645=RNA polymerase Rpb2, domain 3, IPR007647=RNA polymerase Rpb2, domain 5, IPR007641=RNA polymerase Rpb2, domain 7, IPR014724=RNA polymerase Rpb2, OB-fold, IPR007646=RNA polymerase Rpb2, domain 4, IPR007120=DNA-directed RNA polymerase, subunit 2, domain 6, IPR015712=DNA-directed RNA polymerase, subunit 2, IPR007644=RNA polymerase, beta subunit, protrusion, IPR007642=RNA polymerase Rpb2, domain 2, IPR007121=RNA polymerase, beta subunit, conserved site" CG8344 16-Dec-15 2015_12 ENSDARG00000062915(polr3b) YOR207C(RET1) WBGene00017300(F09F7.3) ENSXETG00000005721(POLR3B) ENSMUSG00000034453(Polr3b) ENSG00000013503(POLR3B) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0259145 CG42260 http://flybase.net/reports/FBgn0259145.html "FBgn0034777, FBgn0034775" protein_coding_gene 0005221=intracellular cyclic nucleotide activated cation channel activity "0019935=cyclic-nucleotide-mediated signaling, 0006812=cation transport, 0055085=transmembrane transport" 0017071=intracellular cyclic nucleotide activated cation channel complex "lincRNA.378, CG13530, CG3536, dmCNG4" "IPR014710=RmlC-like jelly roll fold, IPR018488=Cyclic nucleotide-binding, conserved site, IPR005821=Ion transport domain, IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain" CG42260 16-Dec-15 2015_12 ENSXETG00000017714(HCN1) FBgn0000116 Argk Arginine kinase http://flybase.net/reports/FBgn0000116.html "FBgn0035958, FBgn0052031" protein_coding_gene 0004054=arginine kinase activity 0016310=phosphorylation "0005886=plasma membrane, 0005576=extracellular region, 0005829=cytosol, 0005737=cytoplasm" "argK, AK, ARK, CG5173, AK-1, CG4929, ArgK, insect intestinal mucin iim22, argk, arginine kinase, CG32031" "IPR022414=ATP:guanido phosphotransferase, catalytic domain, IPR022413=ATP:guanido phosphotransferase, N-terminal, IPR014746=Glutamine synthetase/guanido kinase, catalytic domain, IPR022415=ATP:guanido phosphotransferase active site, IPR000749=ATP:guanido phosphotransferase" CG32031 16-Dec-15 2015_12 "ENSDARG00000035327(ckma),ENSDARG00000040565(ckmb),ENSDARG00000043257(ckbb),ENSDARG00000069752(ckba),ENSDARG00000039929(ckmt2),ENSDARG00000016598(ckmt1),ENSDARG00000069615(zgc:56085)" "WBGene00018519(F46H5.3),WBGene00021128(W10C8.5),WBGene00017975(F32B5.1),WBGene00013894(ZC434.8),WBGene00009706(F44G3.2)" "ENSXETG00000019108(ckm),ENSXETG00000023038(ckb),ENSXETG00000027612(ckmt1)" "ENSMUSG00000030399(Ckm),ENSMUSG00000001270(Ckb),ENSMUSG00000000308(Ckmt1),ENSMUSG00000021622(Ckmt2)" "ENSG00000166165(CKB),ENSG00000104879(CKM),ENSG00000168775,ENSG00000166998,ENSG00000131730(CKMT2)" " prepupal stage , P | stage P15 " " imaginal disc

, organism

" "lethal,viable,fertile,electrophoretic variant,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC21558 IE 1.960275999 0.601500766 2.093107458 -0.267178247 -0.313583096 0.902376326 FBgn0261239 Hr39 Hormone receptor-like in 39 http://flybase.net/reports/FBgn0261239.html "FBgn0010229, FBgn0014175, FBgn0013458, FBgn0026243" protein_coding_gene "0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding, 0003712=transcription cofactor activity" "0060968=regulation of gene silencing, 0045433=male courtship behavior, veined wing generated song production, 0043401=steroid hormone mediated signaling pathway, 0006355=regulation of transcription, DNA-templated, 0035211=spermathecum morphogenesis, 0016321=female meiosis chromosome segregation" 0005634=nucleus "hormone receptor-like in 39, ftz-F1beta, FTZ-F1B, unnamed, dFTZ-F1beta, CG8676, NR5A-class nuclear hormone receptor, hormone receptor like in 39, DHR39, FTZ-F1beta, HR39, fs(2)neo8, i70, ftz-f1beta, fs(2)04443, DHR30, DHR39/Ftz-F1beta, betaFTZ-E1, EP(2)2490, NR5B1" "IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR016355=Nuclear hormone receptor family 5" CG8676 16-Dec-15 2015_12 WBGene00003681(nhr-91) " embryonic stage | stage 13 , embryonic stage , embryonic stage | stage 16 , embryonic stage | early , embryonic stage -- adult stage " " stomodeum

, embryonic central nervous system

, supraesophageal ganglion

, embryonic/larval hindgut

" FBgn0037092 M6 M6 http://flybase.net/reports/FBgn0037092.html protein_coding_gene "0046956=positive phototaxis, 0001745=compound eye morphogenesis, 0048477=oogenesis" "0005886=plasma membrane, 0016021=integral component of membrane" "dM6a, CG7540" IPR001614=Myelin proteolipid protein PLP CG7540 16-Dec-15 2015_12 "ENSDARG00000004621(gpm6ab),ENSDARG00000055455(gpm6aa),ENSDARG00000005739(gpm6ba),ENSDARG00000001676(gpm6bb),ENSDARG00000057770(plp1a),ENSDARG00000011929(plp1b)" WBGene00017437(nmgp-1) "ENSXETG00000002459(GPM6A),ENSXETG00000013347(gpm6b),ENSXETG00000018134(Q4QQQ6_XENTR)" "ENSMUSG00000031517(Gpm6a),ENSMUSG00000031342(Gpm6b),ENSMUSG00000031425(Plp1)" "ENSG00000150625(GPM6A),ENSG00000046653(GPM6B),ENSG00000123560(PLP1)" "viable,fertile,female sterile,recessive,male fertile,short lived,visible,phototaxis defective,heat sensitive,female fertile,female semi-sterile,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,eye,ommatidium,interommatidial bristle,heat sensitive,follicle cell,border follicle cell,egg chamber" FBgn0261119 Prp19 Pre-RNA processing factor 19 http://flybase.net/reports/FBgn0261119.html "FBgn0010644, FBgn0013969, FBgn0027900" protein_coding_gene 0004842=ubiquitin-protein transferase activity "0000398=mRNA splicing, via spliceosome, 0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction, 0016567=protein ubiquitination, 0000381=regulation of alternative mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0071013=catalytic step 2 spliceosome, 0005875=microtubule associated complex, 0000974=Prp19 complex" "EC2-11, BcDNA:LD02793, l(2)07838, GTP-binding regulatory protein beta chain, CG5519, Prp19, GPB, prp19, Gbp, NM 079059.2, PRP19" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR003613=U box domain, IPR013915=Pre-mRNA-splicing factor 19, IPR020472=G-protein beta WD-40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG5519 16-Dec-15 2015_12 ENSDARG00000015239(prp19) WBGene00020423(T10F2.4) ENSXETG00000011938(prp19) ENSMUSG00000024735(Prpf19) ENSG00000110107(PRPF19) FBgn0032819 CG10463 http://flybase.net/reports/FBgn0032819.html protein_coding_gene "0046872=metal ion binding, 0050660=flavin adenine dinucleotide binding, 0017150=tRNA dihydrouridine synthase activity" "0008033=tRNA processing, 0055114=oxidation-reduction process" "IPR000571=Zinc finger, CCCH-type, IPR018517=tRNA-dihydrouridine synthase, conserved site, IPR013785=Aldolase-type TIM barrel, IPR001269=tRNA-dihydrouridine synthase" CG10463 16-Dec-15 2015_12 ENSDARG00000071228 YLR401C(DUS3) WBGene00021377(Y37E11B.5) ENSXETG00000027405(dus3l) ENSMUSG00000007603(Dus3l) ENSG00000141994(DUS3L) "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0050018 mthl13 methuselah-like 13 http://flybase.net/reports/FBgn0050018.html protein_coding_gene 0004930=G-protein coupled receptor activity "0007186=G-protein coupled receptor signaling pathway, 0006950=response to stress" 0016021=integral component of membrane CG30018 "IPR010596=Methuselah, N-terminal domain, IPR023311=Methuselah ectodomain, domain 2, IPR017981=GPCR, family 2-like" CG30018 16-Dec-15 2015_12 "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" "partially lethal - majority die,some die during pupal stage" FBgn0267486 Ptp36E Protein tyrosine phosphatase 36E http://flybase.net/reports/FBgn0267486.html "FBgn0011699, FBgn0032673" protein_coding_gene 0004725=protein tyrosine phosphatase activity 0006470=protein dephosphorylation "R-PTPk, DPTP36E, CG7180, unnamed" "IPR000242=PTP type protein phosphatase, IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR000387=Tyrosine specific protein phosphatases domain" CG7180 16-Dec-15 2015_12 "ENSDARG00000021151(si:dkey-46n18.4),ENSDARG00000001769(ptpra),ENSDARG00000015891(LOC567443),ENSDARG00000038590(ptprs),ENSDARG00000044635,ENSDARG00000059738,ENSDARG00000071437(ptprc),ENSDARG00000071436,ENSDARG00000045006(ptprga)" WBGene00011755(T13H5.1) "ENSXETG00000017982(PTPRA),ENSXETG00000005190(PTPRE),ENSXETG00000005350(PTPRS)" "ENSMUSG00000027303(Ptpra),ENSMUSG00000041836(Ptpre),ENSMUSG00000026395(Ptprc)" FBgn0039152 Rootletin Rootletin http://flybase.net/reports/FBgn0039152.html protein_coding_gene "0032053=ciliary basal body organization, 0007638=mechanosensory behavior, 0031223=auditory behavior, 0031987=locomotion involved in locomotory behavior" 0035253=ciliary rootlet "Q8IMX3_DROME, rootletin, CG6129, Rootletin" CG6129 16-Dec-15 2015_12 ENSDARG00000017425 WBGene00022500(lfi-1) "ENSXETG00000013421(CROCC),ENSXETG00000012154()" ENSMUSG00000040860(Crocc) ENSG00000058453(CROCC) viable FBgn0037816 CG6345 http://flybase.net/reports/FBgn0037816.html protein_coding_gene "0016740=transferase activity, 0051539=4 iron, 4 sulfur cluster binding" "0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0009451=RNA modification" 149631_at "IPR020612=Methylthiotransferase, conserved site, IPR013848=Methylthiotransferase, N-terminal, IPR023404=Radical SAM, alpha/beta horseshoe, IPR023970=Methylthiotransferase/radical SAM-type protein, IPR005839=Methylthiotransferase, IPR007197=Radical SAM, IPR006638=Elongator protein 3/MiaB/NifB, IPR002792=TRAM domain" CG6345 16-Dec-15 2015_12 ENSDARG00000044925(zgc:162738) WBGene00017776(F25B5.5) ENSXETG00000004314(cdk5rap1) ENSMUSG00000027487(Cdk5rap1) ENSG00000101391(CDK5RAP1) viable FBgn0034791 EMC8-9 ER Membrane protein Complex 8-9 http://flybase.net/reports/FBgn0034791.html "FBgn0061366, FBgn0064784" protein_coding_gene "0005875=microtubule associated complex, 0012505=endomembrane system" "CG3501, EMC8/9, BcDNA:SD01117" IPR005366=Uncharacterised protein family UPF0172 CG3501 16-Dec-15 2015_12 "ENSDARG00000017093(cox4nb),ENSDARG00000034633(fam158a)" WBGene00009118(F25H2.4) "ENSXETG00000025153(BC063338.1),ENSXETG00000014614(FAM158A)" "ENSMUSG00000031819(Cox4nb),ENSMUSG00000022217(Fam158a)" "ENSG00000131148(COX4NB),ENSG00000100908(FAM158A)" viable FBgn0031575 Cep97 http://flybase.net/reports/FBgn0031575.html protein_coding_gene 0008599=protein phosphatase type 1 regulator activity 0007099=centriole replication 0000242=pericentriolar material "DCep97, CT13231, CG3980" "IPR001611=Leucine-rich repeat, IPR000048=IQ motif, EF-hand binding site" CG3980 16-Dec-15 2015_12 ENSDARG00000027857(cep97) ENSXETG00000009170(CEP97) ENSMUSG00000022604(Cep97) ENSG00000182504(CEP97) viable FBgn0027055 CSN3 COP9 signalosome subunit 3 http://flybase.net/reports/FBgn0027055.html protein_coding_gene "0048140=male germ-line cyst encapsulation, 0007095=mitotic G2 DNA damage checkpoint, 0048142=germarium-derived cystoblast division, 0007281=germ cell development, 0046331=lateral inhibition, 0010388=cullin deneddylation, 0051726=regulation of cell cycle, 0050821=protein stabilization, 0036099=female germ-line stem cell maintenance" 0008180=COP9 signalosome "CH3, CG18332, DCH3, COP9 complex homolog subunit 3, Dch3, Drosophila COP9 signalosome homolog 3, dCSN3, FBgn0027055, Csn3" "IPR000717=Proteasome component (PCI) domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG18332 16-Dec-15 2015_12 ENSDARG00000008623 WBGene00000815(csn-3) ENSXETG00000005742(cops3) ENSMUSG00000019373(Cops3) ENSG00000141030(COPS3) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC25919 K 0.450105356 -0.441053706 0.274359368 -1.100060675 1.752507415 1.526982907 FBgn0042710 Hex-t2 Hex-t2 http://flybase.net/reports/FBgn0042710.html "FBgn0029168, FBgn0039426, FBgn0044670, FBgn0052849" protein_coding_gene "0004340=glucokinase activity, 0005536=glucose binding, 0019158=mannokinase activity, 0004396=hexokinase activity, 0008865=fructokinase activity, 0005524=ATP binding" "0006000=fructose metabolic process, 0006006=glucose metabolic process, 0006096=glycolytic process, 0046835=carbohydrate phosphorylation, 0006013=mannose metabolic process, 0001678=cellular glucose homeostasis" 0005829=cytosol "hexokinase, CG32849, anon-WO0140519.203, HK, CG5443, Hex, Hexokinase" "IPR022672=Hexokinase, N-terminal, IPR019807=Hexokinase, binding site, IPR022673=Hexokinase, C-terminal, IPR001312=Hexokinase" CG32849 16-Dec-15 2015_12 "ENSDARG00000026964(hk2),ENSDARG00000039452(hk1),ENSDARG00000038703(hkdc1),ENSDARG00000068006(gck)" "YFR053C(HXK1),YGL253W(HXK2)" WBGene00008780(F14B4.2) "ENSXETG00000019003(GCK),ENSXETG00000019639()" ENSMUSG00000041798(Gck) "ENSG00000106633(GCK),ENSG00000159399(HK2),ENSG00000156515(HK1),ENSG00000156510(HKDC1)" viable FBgn0034068 casp caspar http://flybase.net/reports/FBgn0034068.html protein_coding_gene "0045861=negative regulation of proteolysis, 0002814=negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0061060=negative regulation of peptidoglycan recognition protein signaling pathway" 0005737=cytoplasm "Caspar, Casper, CASP, CG8400, casper" "IPR006577=UAS, IPR001012=UBX domain, IPR012336=Thioredoxin-like fold, IPR029071=Ubiquitin-related domain" CG8400 16-Dec-15 2015_12 ENSDARG00000022418(faf1) WBGene00018586(ubxn-3) ENSXETG00000002841(FAF1) ENSMUSG00000010517(Faf1) ENSG00000185104(FAF1) "immune response defective,viable,fertile" fat body FBgn0039139 Ime4 Inducer of meiosis 4 http://flybase.net/reports/FBgn0039139.html protein_coding_gene 0016422=mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity "0001510=RNA methylation, 0030707=ovarian follicle cell development, 0030708=germarium-derived female germ-line cyst encapsulation, 0008593=regulation of Notch signaling pathway, 0060968=regulation of gene silencing" 0005634=nucleus "Inducer of MEiosis 4 homolog, IME4, ime4, Mta70, Mta70 homologue, MTA70, CG5933, Inducer of Meiosis 4" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025848=mRNA (2-O-methyladenosine-N(6)-)-methyltransferase, IPR007757=MT-A70-like" CG5933 16-Dec-15 2015_12 ENSDARG00000012827(mettl3) YGL192W(IME4) ENSXETG00000017182(mettl3) ENSMUSG00000022160(Mettl3) ENSG00000165819(METTL3) "partially lethal - majority die,semi-fertile,viable,visible" "egg chamber,nurse cell,supernumerary,oocyte,follicle cell,interfollicle cell,female germline cyst,mesothoracic tergum" FBgn0027550 CG6495 http://flybase.net/reports/FBgn0027550.html protein_coding_gene "BcDNA:GH10711, GH10711" "IPR013980=MANSC domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR011106=Seven cysteines, N-terminal, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site" CG6495 16-Dec-15 2015_12 ENSXETG00000017503(LRP11) ENSG00000120256(LRP11) viable FBgn0033500 CG12913 http://flybase.net/reports/FBgn0033500.html protein_coding_gene 0008376=acetylgalactosaminyltransferase activity "0042060=wound healing, 0030206=chondroitin sulfate biosynthetic process" 0032580=Golgi cisterna membrane dCSGalNAcT1 "IPR008428=Chondroitin N-acetylgalactosaminyltransferase, IPR029044=Nucleotide-diphospho-sugar transferases" CG12913 16-Dec-15 2015_12 "ENSDARG00000040535,ENSDARG00000061400(LOC560826)" "ENSXETG00000000615(CSGALNACT2),ENSXETG00000004463(CSGALNACT1)" "ENSMUSG00000036356(Csgalnact1),ENSMUSG00000042042(Csgalnact2)" "ENSG00000147408(CSGALNACT1),ENSG00000169826(CSGALNACT2)" viable DRSC06228 K 0.142427604 0.386884142 -0.104862685 0.213625082 1.590965295 0.243722824 FBgn0037263 slx1 nuclease slx1 http://flybase.net/reports/FBgn0037263.html protein_coding_gene "0004520=endodeoxyribonuclease activity, 0005515=protein binding, 0017108=5'-flap endonuclease activity" "0006281=DNA repair, 0007095=mitotic G2 DNA damage checkpoint" 0033557=Slx1-Slx4 complex "nuclease SLX1, CG18271, SLX1, CG1827" "IPR027520=Structure-specific endonuclease subunit Slx1, IPR026850=FANCL C-terminal domain, IPR000305=GIY-YIG nuclease superfamily" CG18271 16-Dec-15 2015_12 YBR228W(SLX1) WBGene00018909(slx-1) ENSMUSG00000059772(Giyd2) "ENSG00000132207(SLX1A),ENSG00000181625(SLX1B)" radiation sensitive FBgn0034913 Snap29 Synaptosomal-associated protein 29kDa http://flybase.net/reports/FBgn0034913.html protein_coding_gene "0000149=SNARE binding, 0005484=SNAP receptor activity" "0000046=autophagic vacuole fusion, 0097352=autophagic vacuole maturation, 0007269=neurotransmitter secretion, 1903531=negative regulation of secretion by cell, 0016192=vesicle-mediated transport, 0007030=Golgi organization, 0030100=regulation of endocytosis" 0031201=SNARE complex "MENE(2R)-E, CG11173, ubisnap, SNAP-29, MENE (2R)-E, usnp, SNAP29, Ubisnap, unnamed" IPR000727=Target SNARE coiled-coil homology domain CG11173 16-Dec-15 2015_12 ENSDARG00000038518(si:dkey-178e17.4) WBGene00019305(snap-29) ENSXETG00000022403(snap29) ENSMUSG00000022765(Snap29) ENSG00000099940(SNAP29) "lethal,partially lethal - majority die" embryonic/larval fat body | third instar larval stage FBgn0035577 CG13708 http://flybase.net/reports/FBgn0035577.html protein_coding_gene 0046331=lateral inhibition CT33170 IPR001611=Leucine-rich repeat CG13708 16-Dec-15 2015_12 ENSXETG00000020342(LRRC49) ENSG00000137821(LRRC49) "viable,visible" chaeta FBgn0003076 Pgm phosphoglucose mutase http://flybase.net/reports/FBgn0003076.html FBgn0036572 protein_coding_gene "0004619=phosphoglycerate mutase activity, 0000287=magnesium ion binding, 0004614=phosphoglucomutase activity" "0005992=trehalose biosynthetic process, 0005978=glycogen biosynthetic process, 0060361=flight, 0019388=galactose catabolic process, 0046331=lateral inhibition" 0005829=cytosol "Pgm-1, PGM, pgm, CG5165, Phosphogluconate mutase, Phosphoglucomutase, phosphoglucomutase, PGM-1" "IPR005844=Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR005843=Alpha-D-phosphohexomutase, C-terminal, IPR005845=Alpha-D-phosphohexomutase, alpha/beta/alpha domain II, IPR005841=Alpha-D-phosphohexomutase superfamily, IPR005846=Alpha-D-phosphohexomutase, alpha/beta/alpha domain III, IPR016055=Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR016066=Alpha-D-phosphohexomutase, conserved site" CG5165 16-Dec-15 2015_12 "ENSDARG00000013561(pgm1),ENSDARG00000060745(LOC560297)" "YMR105C(PGM2),YKL127W(PGM1)" WBGene00019890(R05F9.6) "ENSXETG00000010833(pgm1),ENSXETG00000001670(PGM5)" "ENSMUSG00000025791(Pgm2),ENSMUSG00000041731(Pgm5)" "ENSG00000079739(PGM1),ENSG00000154330(PGM5)" "electrophoretic variant,slow,lethal,recessive,viable,fertile,fast,intermediate,visible" chaeta FBgn0050036 CG30036 http://flybase.net/reports/FBgn0050036.html FBgn0033671 protein_coding_gene "0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" "0006486=protein glycosylation, 0007030=Golgi organization" 0016020=membrane CG8976 "IPR002659=Glycosyl transferase, family 31" CG30036 16-Dec-15 2015_12 "ENSDARG00000018971(b3gnt5),ENSDARG00000004396(zgc:101733)" WBGene00019539 "ENSXETG00000016205(B3GALT1),ENSXETG00000004532(B3GALT2),ENSXETG00000004536(BC075347.1),ENSXETG00000002261(),ENSXETG00000011652(),ENSXETG00000006113(),ENSXETG00000006114(),ENSXETG00000006118(),ENSXETG00000006123(),ENSXETG00000002237(B3GNT1)" FBgn0015038 Cyp9b1 Cytochrome P450-9b1 http://flybase.net/reports/FBgn0015038.html protein_coding_gene "0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0005506=iron ion binding, 0020037=heme binding, 0004497=monooxygenase activity" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG4485, P-450, 9b1, P450, CYP9B1" "IPR017972=Cytochrome P450, conserved site, IPR002403=Cytochrome P450, E-class, group IV, IPR001128=Cytochrome P450" CG4485 16-Dec-15 2015_12 ENSDARG00000045627(cyp3a65) YHR007C(ERG11) "WBGene00008810(cyp-13A12),WBGene00008809(cyp-13A11),WBGene00014254(cyp-13A10),WBGene00011677(cyp-13A1),WBGene00011674(cyp-13A8),WBGene00010606(cyp-13B2),WBGene00008519(cyp-13B1)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "ENSMUSG00000056035(Cyp3a11),ENSMUSG00000075551(Cyp3a41a),ENSMUSG00000075552(Cyp3a41b),ENSMUSG00000054417(Cyp3a44),ENSMUSG00000038656(Cyp3a16),ENSMUSG00000029727(Cyp3a13),ENSMUSG00000029630(Cyp3a25),ENSMUSG00000070419(Cyp3a57),ENSMUSG00000061292(Cyp3a59)" "ENSG00000160868(CYP3A4),ENSG00000160870(CYP3A7),ENSG00000106258(CYP3A5),ENSG00000021461(CYP3A43),ENSG00000059377(TBXAS1)" viable FBgn0013751 Awh Arrowhead http://flybase.net/reports/FBgn0013751.html FBgn0002195 protein_coding_gene "0008270=zinc ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0010468=regulation of gene expression, 0007444=imaginal disc development, 0048749=compound eye development" 0005634=nucleus "l(3)63Ea, awh, CG1072, lethal(3)63Ea, arrowhead, l(3)SH9, l(3)63Ea/Awh, l63Ea, l(3)64Ea" "IPR001781=Zinc finger, LIM-type, IPR001356=Homeobox domain, IPR009057=Homeodomain-like" CG1072 16-Dec-15 2015_12 "ENSDARG00000006896(lhx6),ENSDARG00000002330(lhx8a),ENSDARG00000042145(LOC799481),ENSDARG00000052165(LOC557579)" WBGene00002987(lim-4) "ENSXETG00000002992(lhx7/lhx8),ENSXETG00000016325(LHX6)" "ENSMUSG00000028201(Lhx8),ENSMUSG00000026890(Lhx6)" "ENSG00000162624(LHX8),ENSG00000106852(LHX6)" "lethal,recessive,visible,dominant,viable,female fertile,male fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "eye,histoblast nest,salivary gland imaginal ring,eye-antennal disc,photoreceptor cell,precursor,abdominal segment,somatic clone,pupal spiracle,polytene chromosome puff,wing,ventral,vibrissae,anterior vertical bristle,posterior vertical bristle,capitellum,genitalia,coxa,femur,wing disc,eye disc,somatic clone | third instar larval stage" FBgn0259099 DCX-EMAP Doublecortin-domain-containing echinoderm-microtubule-associated protein ortholog http://flybase.net/reports/FBgn0259099.html "FBgn0036456, FBgn0040242, FBgn0036455" protein_coding_gene 0008017=microtubule binding "0035556=intracellular signal transduction, 0007017=microtubule-based process, 0008344=adult locomotory behavior, 0007605=sensory perception of sound, 0035011=melanotic encapsulation of foreign target" 0071683=sensory dendrite "CG13466, doublecortin-domain-containing echinoderm-microtubule-associated protein, unnamed, Doublecortin, CG42247, DCX-EMAP, dmEMAP, anon-71Aa, CG13467" "IPR019775=WD40 repeat, conserved site, IPR005108=HELP, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR003533=Doublecortin domain, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG42247 16-Dec-15 2015_12 "ENSDARG00000042840(eml1),ENSDARG00000008808(eml2),ENSDARG00000058038(LOC100332533),ENSDARG00000034350" WBGene00001248(elp-1) "ENSXETG00000018242(eml2),ENSXETG00000016463(EML1),ENSXETG00000006002(eml4),ENSXETG00000005628(EML3)" "ENSMUSG00000058070(Eml1),ENSMUSG00000040811(Eml2),ENSMUSG00000032624(Eml4),ENSMUSG00000071647(Eml3)" "ENSG00000066629(EML1),ENSG00000125746(EML2),ENSG00000143924(EML4)" DRSC23492 IK -1.37967219 -1.836766142 -0.291744595 0.435675588 -1.572492291 -0.058173641 FBgn0261871 dpr2 defective proboscis extension response 2 http://flybase.net/reports/FBgn0261871.html "FBgn0053507, FBgn0032316, FBgn0032317, FBgn0082864" protein_coding_gene 0007606=sensory perception of chemical stimulus "CG14067, CG14068, Dpr2, unnamed, dpr2, BP1042, CG33507, CT33638, Dpr-2" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013106=Immunoglobulin V-set domain, IPR013098=Immunoglobulin I-set" CG33507 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" "ENSMUSG00000078780(Gm5150),ENSMUSG00000044138(Sirpb1a),ENSMUSG00000078781(Sirpb1b),ENSMUSG00000074677(LOC100038947),ENSMUSG00000037902(Sirpa),ENSMUSG00000078783(Gm9733)" FBgn0041183 Tep1 Thioester-containing protein 1 http://flybase.net/reports/FBgn0041183.html "FBgn0028934, FBgn0032575" protein_coding_gene 0004866=endopeptidase inhibitor activity 0019731=antibacterial humoral response 0005615=extracellular space "TEP1mel, Tep-1, Thiolester containing protein I, Thioester containing protein I, dTEPI, Tep 1, TEP, TEP1, CG18096, Tep1, Tep I, tep1, TepI, BG:DS00365.2" "IPR011626=Alpha-macroglobulin complement component, IPR009048=Alpha-macroglobulin, receptor-binding, IPR019565=Alpha-2-macroglobulin, thiol-ester bond-forming, IPR011625=Alpha-2-macroglobulin, N-terminal 2, IPR019742=Alpha-2-macroglobulin, conserved site, IPR002890=Alpha-2-macroglobulin, N-terminal, IPR001599=Alpha-2-macroglobulin, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG18096 16-Dec-15 2015_12 "ENSDARG00000056314(a2ml),ENSDARG00000041645(sb:cb37),ENSDARG00000041685(LOC100006782),ENSDARG00000056588,ENSDARG00000024892,ENSDARG00000017289,ENSDARG00000017619,ENSDARG00000041639,ENSDARG00000035291,ENSDARG00000053178,ENSDARG00000027924,ENSDARG00000035292,ENSDARG00000041653,ENSDARG00000058274,ENSDARG00000008835" WBGene00013969(ZK337.1) "ENSXETG00000024219(BC093458.1),ENSXETG00000024227(),ENSXETG00000017070(),ENSXETG00000006980(BC091705.1),ENSXETG00000006979(),ENSXETG00000009402(),ENSXETG00000017401(),ENSXETG00000009400()" ENSMUSG00000046186(Cd109) ENSG00000156535(CD109) viable FBgn0053497 Sdic2 Sperm-specific dynein intermediate chain 2 http://flybase.net/reports/FBgn0053497.html protein_coding_gene 0003777=microtubule motor activity 0007018=microtubule-based movement "0036126=sperm flagellum, 0005858=axonemal dynein complex" "CG33497, Sdic:CG33497" "IPR025956=Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG33497 16-Dec-15 2015_12 "ENSDARG00000005756(dync1i2a),ENSDARG00000022487,ENSDARG00000060948(zgc:158394),ENSDARG00000063383(dync1i2b)" YDR488C(PAC11) WBGene00015927(dyci-1) "ENSXETG00000020285(dnci2),ENSXETG00000020277(DYNC1I1)" "ENSMUSG00000027012(Dync1i2),ENSMUSG00000029757(Dync1i1)" "ENSG00000077380(DYNC1I2),ENSG00000158560(DYNC1I1)" FBgn0034796 CG3700 http://flybase.net/reports/FBgn0034796.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "c-SP48, SP48" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG3700 16-Dec-15 2015_12 "ENSXETG00000016792(plat),ENSXETG00000007245(F12),ENSXETG00000005495(HGFAC),ENSXETG00000018616(HABP2),ENSXETG00000010002(),ENSXETG00000004035(PRSS12)" "ENSMUSG00000025075(Habp2),ENSMUSG00000029102(Hgfac),ENSMUSG00000031538(Plat),ENSMUSG00000021822(Plau),ENSMUSG00000021492(F12),ENSMUSG00000027978(Prss12)" FBgn0032456 MRP Multidrug-Resistance like Protein 1 http://flybase.net/reports/FBgn0032456.html protein_coding_gene "0005524=ATP binding, 0043492=ATPase activity, coupled to movement of substances, 0008559=xenobiotic-transporting ATPase activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0031427=response to methotrexate, 0055085=transmembrane transport" "0005886=plasma membrane, 0016021=integral component of membrane" "MRP1, dMRP1, dMRP, dMRP/CG6214, lincRNA.123, Multidrug-resistance protein, multidrug resistance-associated protein, multidrug resistance-like protein 1, CG6214, multidrug resistance like protein, Mrp" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR005292=Multi drug resistance-associated protein" CG6214 16-Dec-15 2015_12 ENSDARG00000014031(abcc2) "YDR135C(YCF1),YLL015W(BPT1)" "WBGene00003407(mrp-1),WBGene00003408(mrp-2)" "ENSXETG00000012239(ABCC3),ENSXETG00000019661(ABCC1)" "ENSMUSG00000023088(Abcc1),ENSMUSG00000020865(Abcc3)" "ENSG00000103222(ABCC1),ENSG00000108846(ABCC3)" "viable,fertile" FBgn0050394 CG30394 http://flybase.net/reports/FBgn0050394.html "FBgn0034619, FBgn0034620, FBgn0046415, FBgn0046416" protein_coding_gene 0015171=amino acid transmembrane transporter activity 0003333=amino acid transmembrane transport "CG10500, anon-WO0172774.187, CG15670, anon-WO0172774.188" "IPR013057=Amino acid transporter, transmembrane domain" CG30394 16-Dec-15 2015_12 WBGene00021765(Y51F10.4) ENSXETG00000015401(SLC38A10) ENSMUSG00000061306(Slc38a10) ENSG00000157637(SLC38A10) viable FBgn0015033 Cyp4d8 Cytochrome P450-4d8 http://flybase.net/reports/FBgn0015033.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "4d8, cytochrome P450, P450, CG4321, P-450" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG4321 16-Dec-15 2015_12 YMR015C(ERG5) viable FBgn0031974 CG12560 http://flybase.net/reports/FBgn0031974.html protein_coding_gene 0008080=N-acetyltransferase activity 0016573=histone acetylation "IPR000182=GNAT domain, IPR016181=Acyl-CoA N-acyltransferase, IPR013653=FR47-like" CG12560 16-Dec-15 2015_12 ENSDARG00000051954(LOC799646) "ENSG00000166840(GLYATL1),ENSG00000203972(GLYATL3),ENSG00000156689(GLYATL2),ENSG00000149124(GLYAT)" viable FBgn0265140 Meltrin Meltrin http://flybase.net/reports/FBgn0265140.html "FBgn0051314, FBgn0038253, FBgn0051385, FBtr0082972, FBpp0082431, FBtr0082973, FBpp0082432, FBgn0062267" protein_coding_gene "0042802=identical protein binding, 0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0051259=protein oligomerization, 0006509=membrane protein ectodomain proteolysis" "0098595=perivitelline space, 0016021=integral component of membrane" "Neu3, DMeltrin, meltrin, dMeltrin-alpha, CG31385, Neuroectoderm-expressed 3, FBgn0051314, Meltrin-like, CG31314, CG7649, CT23341" "IPR001762=Disintegrin domain, IPR013032=EGF-like, conserved site, IPR000742=EGF-like domain, IPR001590=Peptidase M12B, ADAM/reprolysin, IPR024079=Metallopeptidase, catalytic domain, IPR006586=ADAM, cysteine-rich, IPR002870=Peptidase M12B, propeptide" CG7649 16-Dec-15 2015_12 "ENSDARG00000035514,ENSDARG00000001452(adam8a),ENSDARG00000057644" WBGene00000074(adm-2) "ENSXETG00000022538(ADAM12),ENSXETG00000011758(ADAM33),ENSXETG00000015156(ADAM9)" "ENSMUSG00000054555(Adam12),ENSMUSG00000011256(Adam19),ENSMUSG00000027318(Adam33),ENSMUSG00000031555(Adam9),ENSMUSG00000028041(Adam15)" "ENSG00000148848(ADAM12),ENSG00000135074(ADAM19),ENSG00000149451(ADAM33),ENSG00000143537(ADAM15),ENSG00000151651" embryonic stage | blastoderm ventral ectoderm anlage

FBgn0033830 CG10814 http://flybase.net/reports/FBgn0033830.html protein_coding_gene 0008336=gamma-butyrobetaine dioxygenase activity 0055114=oxidation-reduction process "IPR003819=TauD/TfdA-like domain, IPR010376=Domain of unknown function DUF971" CG10814 16-Dec-15 2015_12 ENSDARG00000036135(bbox1) YHL021C(AIM17) WBGene00001522(gbh-1) ENSXETG00000004606(BBOX1) ENSMUSG00000041660(Bbox1) ENSG00000129151(BBOX1) viable FBgn0002626 RpL32 Ribosomal protein L32 http://flybase.net/reports/FBgn0002626.html "FBgn0010264, FBgn0047051" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0000228=nuclear chromosome, 0005730=nucleolus, 0005840=ribosome, 0005737=cytoplasm, 0022625=cytosolic large ribosomal subunit" "rp49, Ribosomal protein 49, Rpl32, RPL32, Rp-49, Rp49/RpL32, ribosomal protein L32, Minute(3)99D, CG7939, r-protein 49, Rp49, Ribosomal protein 49/L32, RP49, bs30a02.y1, RP-49, 143250_at, L32, rp49/RpL32, BcDNA:RH03940, M(3)99D" "IPR018263=Ribosomal protein L32e, conserved site, IPR001515=Ribosomal protein L32e" CG7939 16-Dec-15 2015_12 ENSDARG00000054818(zgc:136952) YBL092W(RPL32) WBGene00004446(rpl-32) "ENSXETG00000015507(rpl32),ENSXETG00000001461(rpl32)" "ENSMUSG00000057841(Rpl32),ENSMUSG00000068969,ENSMUSG00000063816(Gm4987)" ENSG00000144713(RPL32) wild-type DRSC16835 EK 1.098929632 0.638110286 3.270627075 -3.967281525 1.764939837 2.840864331 FBgn0024996 eIF2B-ë_ eIF2B-ë_ http://flybase.net/reports/FBgn0024996.html protein_coding_gene "0005085=guanyl-nucleotide exchange factor activity, 0003743=translation initiation factor activity, 0046523=S-methyl-5-thioribose-1-phosphate isomerase activity" "0071456=cellular response to hypoxia, 0006413=translational initiation, 0006446=regulation of translational initiation, 0019509=L-methionine biosynthetic process from methylthioadenosine" "0005851=eukaryotic translation initiation factor 2B complex, 0005737=cytoplasm, 0005829=cytosol" "EIF2b, eIF2Bbeta, DMC100G10.3, EG:100G10.3, eIF2B-beta, CG2677" IPR000649=Initiation factor 2B-related CG2677 16-Dec-15 2015_12 ENSDARG00000041397(eif2b2) YLR291C(GCD7) WBGene00012950(Y47H9C.7) ENSXETG00000013261(EIF2B2) ENSMUSG00000004788(Eif2b2) ENSG00000119718(EIF2B2) "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0037802 Sirt6 Sirtuin 6 http://flybase.net/reports/FBgn0037802.html protein_coding_gene "0070403=NAD+ binding, 0004407=histone deacetylase activity" "0016575=histone deacetylation, 0031937=positive regulation of chromatin silencing, 0008340=determination of adult lifespan" 0005634=nucleus "D.mel4, dSIRT6, Sirt6, dmSRT408, CG6284" "IPR003000=Sirtuin family, IPR029035=DHS-like NAD/FAD-binding domain, IPR026590=Sirtuin family, catalytic core domain" CG6284 16-Dec-15 2015_12 ENSDARG00000039945(sirt6) WBGene00004803(sir-2.4) ENSXETG00000027525(sirt6) ENSMUSG00000034748(Sirt6) ENSG00000077463(SIRT6) "short lived,viable" FBgn0031359 Rim2 Rim2 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0031359.html protein_coding_gene 0022857=transmembrane transporter activity "0030302=deoxynucleotide transport, 0048311=mitochondrion distribution, 0040011=locomotion, 0007005=mitochondrion organization, 0006390=transcription from mitochondrial promoter, 0045333=cellular respiration, 0006839=mitochondrial transport" "0031966=mitochondrial membrane, 0005739=mitochondrion" "CG18317, drim2" "IPR002030=Mitochondrial brown fat uncoupling protein, IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG18317 16-Dec-15 2015_12 "ENSDARG00000038731(slc25a36a),ENSDARG00000015915(slc25a36b),ENSDARG00000039931(slc25a33)" YBR192W(RIM2) WBGene00011662(T09F3.2) ENSXETG00000020731(SLC25A36) ENSMUSG00000032449(Slc25a36) "ENSG00000114120(SLC25A36),ENSG00000171612(SLC25A33)" "viable,long lived" FBgn0031868 Rat1 http://flybase.net/reports/FBgn0031868.html protein_coding_gene "0003676=nucleic acid binding, 0008409=5'-3' exonuclease activity, 0004534=5'-3' exoribonuclease activity" "0022008=neurogenesis, 0000738=DNA catabolic process, exonucleolytic" 0005634=nucleus "Xrn2, CG10354, dRAT1, XRN2, RAT1, Rat1, dhp1" "IPR004859=Putative 5-3 exonuclease, IPR027073=5'-3' exoribonuclease" CG10354 16-Dec-15 2015_12 ENSDARG00000069092(xrn2) WBGene00006964(xrn-2) ENSXETG00000023501(xrn2) ENSMUSG00000027433(Xrn2) ENSG00000088930(XRN2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0038360 CG9590 http://flybase.net/reports/FBgn0038360.html protein_coding_gene IPR007998=Protein of unknown function DUF719 CG9590 16-Dec-15 2015_12 ENSDARG00000008287(fam114a1) ENSXETG00000018498(FAM114A1) "ENSMUSG00000020523(Fam114a2),ENSMUSG00000029185(Fam114a1)" "ENSG00000055147(FAM114A2),ENSG00000197712(FAM114A1)" viable FBgn0015032 Cyp4c3 Cytochrome P450-4c3 http://flybase.net/reports/FBgn0015032.html protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "4C3, cyp4c3, CG1438, P450, P-450, cytochrome P450" "IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site" CG1438 16-Dec-15 2015_12 "ENSDARG00000062132(cyp4v2),ENSDARG00000070381,ENSDARG00000061585" YMR015C(ERG5) "WBGene00010354(cyp-31A2),WBGene00021200(cyp-31A3)" "ENSXETG00000005868(),ENSXETG00000027605()" ENSMUSG00000079057(Cyp4v3) ENSG00000145476(CYP4V2) viable FBgn0030588 CG9521 http://flybase.net/reports/FBgn0030588.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0016491=oxidoreductase activity, 0008812=choline dehydrogenase activity" "0045455=ecdysteroid metabolic process, 0055114=oxidation-reduction process" Dm GMCtheta2 "IPR012132=Glucose-methanol-choline oxidoreductase, IPR007867=Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172=Glucose-methanol-choline oxidoreductase, N-terminal" CG9521 16-Dec-15 2015_12 WBGene00007917(C34C6.4) ENSMUSG00000015970(Chdh) ENSG00000016391(CHDH) "lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015381 dsf dissatisfaction http://flybase.net/reports/FBgn0015381.html protein_coding_gene "0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0043565=sequence-specific DNA binding, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity" "0035206=regulation of hemocyte proliferation, 0007619=courtship behavior, 0045924=regulation of female receptivity, 0018993=somatic sex determination, 0007530=sex determination, 0018991=oviposition, 0007620=copulation, 0048047=mating behavior, sex discrimination, 0007617=mating behavior, 0008049=male courtship behavior, 0043401=steroid hormone mediated signaling pathway, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG9019, dissatisfaction, NR2E4, Dsf, DSF, Dissatisfaction" "IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR003068=Transcription factor COUP, IPR013088=Zinc finger, NHR/GATA-type, IPR001723=Nuclear hormone receptor" CG9019 16-Dec-15 2015_12 WBGene00003657(nhr-67) ENSMUSG00000019803(Nr2e1) ENSG00000112333(NR2E1) " larval stage , embryonic stage -- adult stage , pupal stage , pharate adult stage " " larval brain | anterior | restricted

, anterior protocerebral neuromere | restricted

, adult brain | restricted

, embryonic/larval salivary gland

" "mating defective,neuroanatomy defective,behavior defective,male limited,male,recessive,courtship behavior defective,female,partially lethal - majority die,visible,melanotic necrosis,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,viable,fertile,lethal - all die before end of larval stage,some die during larval stage,wild-type" "adult abdominal segment 5 & synapse | malecl7),leg,distal,eye,ommatidium,interommatidial bristle,pigment cell,ectopic,third segment of antenna,pupa,posterior,arista,wing,mesothoracic tergum,tarsal segment,metathoracic leg" DRSC03524 IK -0.466395363 -1.996815698 -0.778496291 0.108042246 1.447215464 1.571732593 FBgn0031344 CG7420 http://flybase.net/reports/FBgn0031344.html protein_coding_gene "IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR000408=Regulator of chromosome condensation, RCC1" CG7420 16-Dec-15 2015_12 "ENSDARG00000070986(sergef),ENSDARG00000063128" YAL020C(ATS1) ENSMUSG00000030839(Sergef) ENSG00000129158(SERGEF) "viable,fertile" FBgn0086605 CG9853 http://flybase.net/reports/FBgn0086605.html "FBgn0037243, FBgn0084030, FBgn0046267" protein_coding_gene "BEST:LD21829, CG41469" IPR007317=Uncharacterised protein family UPF0363 CG9853 16-Dec-15 2015_12 ENSDARG00000024398 WBGene00017825(cee-1) ENSXETG00000021638(C7orf20) ENSMUSG00000025858(Get4) ENSG00000105972 FBgn0016687 Nurf-38 Nucleosome remodeling factor - 38kD http://flybase.net/reports/FBgn0016687.html FBgn0021828 protein_coding_gene "0070615=nucleosome-dependent ATPase activity, 0000287=magnesium ion binding, 0004427=inorganic diphosphatase activity" "0006796=phosphate-containing compound metabolic process, 0006338=chromatin remodeling, 0045747=positive regulation of Notch signaling pathway, 0035206=regulation of hemocyte proliferation, 0042766=nucleosome mobilization, 0035076=ecdysone receptor-mediated signaling pathway, 0006351=transcription, DNA-templated" "0016589=NURF complex, 0005737=cytoplasm, 0005634=nucleus" "Nurf38, N38, pyrophosphatase, 38, Nucleosome remodeling factor-38 kDa, p38/NURF-38, NURF-38, dNURF, CG4634, Nucleosome remodeling factor, Inorganic pyrophosphatase, l(2)k16102, Nurf 38, NURF, NURF 38, NURF38, p38" IPR008162=Inorganic pyrophosphatase CG4634 16-Dec-15 2015_12 "ENSDARG00000030441(ppa1),ENSDARG00000009685(ppa2),ENSDARG00000034201(pp)" YBR011C(IPP1) WBGene00008149(pyp-1) "ENSXETG00000006145(pp),ENSXETG00000014102(ppa2)" "ENSMUSG00000028013(Ppa2),ENSMUSG00000020089(Ppa1)" "ENSG00000138777(PPA2),ENSG00000180817(PPA1)" "lethal,recessive,female semi-sterile,female fertile" DRSC26858 K 0.452209491 -0.118875599 -0.793648108 0.276111151 -1.511973324 -0.405770392 FBgn0031081 Nep3 Neprilysin 3 http://flybase.net/reports/FBgn0031081.html protein_coding_gene "0008237=metallopeptidase activity, 0004222=metalloendopeptidase activity" 0006508=proteolysis 0016021=integral component of membrane "DmeNEP3, CEC, nep3, CG9565, NEP3, dNEP3" "IPR018497=Peptidase M13, C-terminal domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain, IPR024079=Metallopeptidase, catalytic domain" CG9565 16-Dec-15 2015_12 ENSDARG00000061737(zgc:154079) ENSXETG00000017285(ECE2) "ENSMUSG00000057530(Ece1),ENSMUSG00000022842(Ece2)" "ENSG00000117298(ECE1),ENSG00000145194(ECE2)" viable FBgn0002031 l(2)37Cc lethal (2) 37Cc http://flybase.net/reports/FBgn0002031.html FBgn0032758 protein_coding_gene "0002165=instar larval or pupal development, 0071456=cellular response to hypoxia" "0005739=mitochondrion, 0005811=lipid particle, 0005875=microtubule associated complex, 0005737=cytoplasm, 0005740=mitochondrial envelope, 0016020=membrane" "CG10691, l(2)Cc, Cc, transcription unit No. 4, l (2) 37Cc, fs(2)HH32" "IPR001107=Band 7 protein, IPR000163=Prohibitin" CG10691 16-Dec-15 2015_12 ENSDARG00000057414(LOC100334735) YGR132C(PHB1) WBGene00004014(phb-1) ENSXETG00000027802(phb) ENSMUSG00000038845(Phb) ENSG00000167085(PHB) embryonic stage&&larval stage&&adult stage "female sterile,partially lethal - majority die,recessive,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,heat sensitive,visible,male sterile,body color defective,dominant,some die during pupal stage" "egg,wing,macrochaeta,melanotic mass & adult abdomen,egg chamber,cystocyte,yolk,trichogen cell,mesothoracic tergum" DRSC03563 K -1.497571604 -0.474289239 -1.325147187 -1.419442079 1.561792802 -0.182566357 FBgn0033373 CG8080 http://flybase.net/reports/FBgn0033373.html FBgn0050346 protein_coding_gene 0003951=NAD+ kinase activity "0006741=NADP biosynthetic process, 0019674=NAD metabolic process" 0005739=mitochondrion CG30346 "IPR012355=NAD kinase, eukaryotic, IPR002504=NAD kinase, IPR017438=Inorganic polyphosphate/ATP-NAD kinase, domain 1, IPR016064=NAD kinase/diacylglycerol kinase-like domain, IPR017437=ATP-NAD kinase, PpnK-type, all-beta" CG8080 16-Dec-15 2015_12 ENSDARG00000007181(zgc:92417) WBGene00012463(Y17G7B.10) ENSXETG00000004798(C5orf33) ENSMUSG00000022253(1110020G09Rik) ENSG00000152620(NADKD1) "viable,visible" trichogen cell FBgn0053837 His1:CG33837 His1:CG33837 http://flybase.net/reports/FBgn0053837.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0005634=nucleus, 0000786=nucleosome" CG33837 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5, IPR005818=Linker histone H1/H5, domain H15" CG33837 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0015283 Rpn10 Regulatory particle non-ATPase 10 http://flybase.net/reports/FBgn0015283.html protein_coding_gene "0008270=zinc ion binding, 0031593=polyubiquitin binding, 0031624=ubiquitin conjugating enzyme binding" "0000070=mitotic sister chromatid segregation, 0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0005838=proteasome regulatory particle, 0005737=cytoplasm, 0008540=proteasome regulatory particle, base subcomplex, 0005634=nucleus, 0000502=proteasome complex" "pros54, CG7619, Pros54, Rpn10, subunit S5a, Rpn10/p54, p54, S5A, unnamed, dRpn10, DmS5a, Proteasome 54kD subunit, S5a, mu-54, 7619, 54 kda mu particle subunit of 26S protease" "IPR003903=Ubiquitin interacting motif, IPR002035=von Willebrand factor, type A, IPR027040=Proteasome subunit Rpn10" CG7619 16-Dec-15 2015_12 "ENSDARG00000036715(psmd4a),ENSDARG00000070696,ENSDARG00000023279(psmd4b)" YHR200W(RPN10) WBGene00004466(rpn-10) ENSXETG00000020049(psmd4) ENSMUSG00000005625(Psmd4) ENSG00000159352(PSMD4) "viable,fertile,lethal - all die before end of larval stage,some die during larval stage,some die during third instar larval stage,lethal,partially lethal - majority die,developmental rate defective,mitotic cell cycle defective" "embryonic/larval brain,pupal cuticle,nuclear chromosome | larval stage,condensed nuclear chromosome | larval stage,ventral nerve cord" DRSC11876 IK -1.10666165 -2.047158155 -1.111297765 -1.101010214 2.921975387 0.034796142 FBgn0032451 spict spichthyin http://flybase.net/reports/FBgn0032451.html protein_coding_gene 0015095=magnesium ion transmembrane transporter activity "0030514=negative regulation of BMP signaling pathway, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0015693=magnesium ion transport, 0007476=imaginal disc-derived wing morphogenesis" 0016021=integral component of membrane "spg6, CG12292, Spict" IPR008521=Magnesium transporter NIPA CG12292 16-Dec-15 2015_12 "ENSDARG00000026682(zgc:101583),ENSDARG00000055912(nipa2)" WBGene00021820(nipa-1) "ENSXETG00000004144(nipa2),ENSXETG00000009832(NIPAL1),ENSXETG00000018169(BC091087.1),ENSXETG00000001501(TEgg120n23.1)" "ENSMUSG00000030452(Nipa2),ENSMUSG00000067219(Nipal1),ENSMUSG00000020411(Nipal4)" "ENSG00000140157(NIPA2),ENSG00000163293(NIPAL1),ENSG00000172548(NIPAL4)" "viable,fertile,developmental rate defective,neuroanatomy defective" "embryonic/larval neuromuscular junction,bouton,supernumerary,posterior crossvein,wing,type I bouton" FBgn0024992 CG2658 http://flybase.net/reports/FBgn0024992.html FBgn0015870 protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding, 0008237=metallopeptidase activity, 0005524=ATP binding, 0016887=ATPase activity" 0006508=proteolysis "0005739=mitochondrion, 0016021=integral component of membrane" "paraplegin_DROME, anon-3Ba, EG:100G10.7, Dm100G10.aj, unnamed" "IPR011546=Peptidase M41, FtsH extracellular, IPR003593=AAA+ ATPase domain, IPR000642=Peptidase M41, IPR005936=Peptidase, FtsH, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG2658 16-Dec-15 2015_12 ENSDARG00000068187(wu:fd15f08) WBGene00021425(ppgn-1) ENSXETG00000019834(SPG7) ENSMUSG00000000738(Spg7) ENSG00000197912(SPG7) "viable,fertile" FBgn0037754 CG8500 http://flybase.net/reports/FBgn0037754.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" 0007264=small GTPase mediated signal transduction 0016020=membrane Q9VH66 "IPR020849=Small GTPase superfamily, Ras type, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8500 16-Dec-15 2015_12 "ENSDARG00000009372(LOC565395),ENSDARG00000028066(diras1a)" "ENSXETG00000000810(DIRAS2),ENSXETG00000012389(),ENSXETG00000003716(DIRAS1)" "ENSMUSG00000047842(Diras2),ENSMUSG00000043670(Diras1)" "ENSG00000165023(DIRAS2),ENSG00000176490(DIRAS1)" "viable,fertile" FBgn0032305 CG6700 http://flybase.net/reports/FBgn0032305.html protein_coding_gene IPR005062=SAC3/GANP/THP3 CG6700 16-Dec-15 2015_12 YPR045C() WBGene00017158(F01F1.1) ENSXETG00000003390(LENG8) ENSMUSG00000035545(Leng8) ENSG00000167615(LENG8) lethal FBgn0015520 nonA-l nonA-like http://flybase.net/reports/FBgn0015520.html FBgn0026581 protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0008187=poly-pyrimidine tract binding" "0000398=mRNA splicing, via spliceosome" 0005681=spliceosomal complex "PSF, CG10328, Z, LD09360, nonA-1, no-on transient A-like, no-on transient A gene, BEST:LD09360, nonA 1, predicted gene Z" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain, IPR012975=NOPS" CG10328 16-Dec-15 2015_12 "ENSDARG00000020482(nono),ENSDARG00000011564(sfpq),ENSDARG00000006621(pspc1)" WBGene00017778(psf-1) "ENSXETG00000009682(SFPQ),ENSXETG00000020868(nono)" "ENSMUSG00000028820(Sfpq),ENSMUSG00000021938(Pspc1),ENSMUSG00000031311(Nono)" "ENSG00000116560(SFPQ),ENSG00000121390(PSPC1),ENSG00000147140(NONO)" "viable,fertile,partially lethal - majority die,visible,lethal,wild-type" "eye,wing vein" FBgn0063670 CG40228 http://flybase.net/reports/FBgn0063670.html "FBgn0058228, FBan0040228" protein_coding_gene BcDNA:RE67573 IPR007808=Transcription elongation factor 1 CG40228 16-Dec-15 2015_12 ENSDARG00000043601(elof1) YKL160W(ELF1) WBGene00013219(Y54G11A.11) ENSXETG00000016731(TGas034f20.1) "ENSMUSG00000013822(Elof1),ENSMUSG00000073524(Gm10526),ENSMUSG00000073525(Gm10527),ENSMUSG00000073521(Gm10525),ENSMUSG00000073526(AA684185)" ENSG00000130165(ELOF1) FBgn0025866 CalpB Calpain-B http://flybase.net/reports/FBgn0025866.html protein_coding_gene "0005509=calcium ion binding, 0004198=calcium-dependent cysteine-type endopeptidase activity" "0006508=proteolysis, 0007298=border follicle cell migration, 0016540=protein autoprocessing" "0005737=cytoplasm, 0016020=membrane" "calpain B, CALPB, Calpain B, calpB, CG8107, calpainB" "IPR002048=EF-hand domain, IPR022684=Peptidase C2, calpain family, IPR022682=Peptidase C2, calpain, large subunit, domain III, IPR001300=Peptidase C2, calpain, catalytic domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR022683=Peptidase C2, calpain, domain III, IPR000169=Cysteine peptidase, cysteine active site" CG8107 16-Dec-15 2015_12 "ENSDARG00000012341(capn9),ENSDARG00000045199(zgc:55262),ENSDARG00000055338(LOC565825),ENSDARG00000041864(capn3),ENSDARG00000052748(LOC565106),ENSDARG00000055592(capn2b),ENSDARG00000034211(capn2l),ENSDARG00000052702(capn1a),ENSDARG00000052720,ENSDARG00000004030,ENSDARG00000055715(LOC100332861),ENSDARG00000043035" "WBGene00000542(clp-1),WBGene00000547(clp-7)" "ENSXETG00000023310(CAPN9),ENSXETG00000023299(capn1),ENSXETG00000018607(capn8),ENSXETG00000018599(capn2)" "ENSMUSG00000031981(Capn9),ENSMUSG00000079110(Capn3),ENSMUSG00000024942(Capn1),ENSMUSG00000026509(Capn2),ENSMUSG00000038599(Capn8)" "ENSG00000135773(CAPN9),ENSG00000092529(CAPN3),ENSG00000014216(CAPN1),ENSG00000162909(CAPN2)" "viable,fertile" border follicle cell FBgn0010317 CycJ Cyclin J http://flybase.net/reports/FBgn0010317.html protein_coding_gene 0016538=cyclin-dependent protein serine/threonine kinase regulator activity "0060966=regulation of gene silencing by RNA, 0007293=germarium-derived egg chamber formation, 0007067=mitotic nuclear division, 0045448=mitotic cell cycle, embryonic" 0005634=nucleus "cdi5, Cdi5, Cyclin-dependent kinase interactor 5, CDI5, cyclinJ, cyclin J, CG10308, cycJ" "IPR004367=Cyclin, C-terminal domain, IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal" CG10308 16-Dec-15 2015_12 ENSDARG00000059917 ENSXETG00000012186(CCNJ) "ENSMUSG00000025010(Ccnj),ENSMUSG00000044707(Ccnjl)" "ENSG00000107443(CCNJ),ENSG00000135083(CCNJL)" " embryonic stage | early , adult stage | female " " embryonic stage | syncytial blastoderm , adult stage | female , embryonic stage | 0-3 hr , embryonic stage | cycle 1-10 , egg stage | unfertilized egg " " nurse cell

, unfertilized egg

" viable FBgn0031854 TTLL3A Tubulin tyrosine ligase-like 3A http://flybase.net/reports/FBgn0031854.html protein_coding_gene 0004835=tubulin-tyrosine ligase activity 0018094=protein polyglycylation "CG11323, dmTTLL3A" IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase CG11323 16-Dec-15 2015_12 ENSDARG00000053728(ttll3) "ENSXETG00000026123(),ENSXETG00000008605(),ENSXETG00000007995(),ENSXETG00000023542(),ENSXETG00000007997(),ENSXETG00000017893()" "ENSMUSG00000030276(Ttll3),ENSMUSG00000022388(Ttll8)" "ENSG00000214021(TTLL3),ENSG00000138892(TTLL8)" viable FBgn0004592 Eig71Ee Ecdysone-induced gene 71Ee http://flybase.net/reports/FBgn0004592.html protein_coding_gene 0005198=structural molecule activity "0042381=hemolymph coagulation, 0007594=puparial adhesion" 0005576=extracellular region "L71-7, I71-7, gene VII, gene-VII, 71E-Gene-VII, eig71Ee, L71, Gene VII, gp150, VII, CG7604" CG7604 16-Dec-15 2015_12 "ENSXETG00000004758(),ENSXETG00000006248(),ENSXETG00000017620(),ENSXETG00000004626()" ENSMUSG00000049008(BB014433) FBgn0032692 CG15161 http://flybase.net/reports/FBgn0032692.html protein_coding_gene "0042073=intraciliary transport, 0042384=cilium assembly" "0030992=intraciliary transport particle B, 0005929=cilium" IFT46 IPR022088=Intraflagellar transport complex B protein 46 CG15161 16-Dec-15 2015_12 ENSDARG00000011240(ift46) WBGene00001122(dyf-6) ENSXETG00000021567(C11orf60) ENSMUSG00000002031(Ift46) ENSG00000118096(IFT46) viable FBgn0033739 Dyb Dystrobrevin http://flybase.net/reports/FBgn0033739.html protein_coding_gene "0008270=zinc ion binding, 0008307=structural constituent of muscle, 0008092=cytoskeletal protein binding" "0016014=dystrobrevin complex, 0016010=dystrophin-associated glycoprotein complex" "CG8529, DmDYB, Dystrobrevin-like" "IPR000433=Zinc finger, ZZ-type, IPR015153=EF-hand domain, type 1, IPR015154=EF-hand domain, type 2, IPR011992=EF-hand domain pair, IPR017432=Distrobrevin" CG8529 16-Dec-15 2015_12 "ENSDARG00000013020(dtnb),ENSDARG00000037388(LOC100330704),ENSDARG00000031015(dtna)" WBGene00001115(dyb-1) ENSXETG00000001233(DTNB) "ENSMUSG00000071454(Dtnb),ENSMUSG00000024302(Dtna)" "ENSG00000138101(DTNB),ENSG00000134769(DTNA)" viable FBgn0039358 CG5028 http://flybase.net/reports/FBgn0039358.html protein_coding_gene "0000287=magnesium ion binding, 0004449=isocitrate dehydrogenase (NAD+) activity, 0051287=NAD binding" 0006099=tricarboxylic acid cycle "0005739=mitochondrion, 0005875=microtubule associated complex, 0005759=mitochondrial matrix" "IPR024084=Isopropylmalate dehydrogenase-like domain, IPR001804=Isocitrate and isopropylmalate dehydrogenases family, IPR004434=Isocitrate dehydrogenase NAD-dependent" CG5028 16-Dec-15 2015_12 "ENSDARG00000036986(zgc:113076),ENSDARG00000023648" YNL037C(IDH1) "WBGene00016266(C30F12.7),WBGene00009440(F35G12.2)" ENSXETG00000000731(idh3g) ENSMUSG00000002010(Idh3g) ENSG00000067829(IDH3G) FBgn0264606 Fife Fife http://flybase.net/reports/FBgn0264606.html "FBgn0035366, FBgn0027741, FBgn0035367, FBgn0263177, FBgn0035364" protein_coding_gene "0001956=positive regulation of neurotransmitter secretion, 2000809=positive regulation of synaptic vesicle clustering" 0048786=presynaptic active zone "CG43955, fife, CG43375, CG16976, anon-EST:Posey171, CG12187, CG14950" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR000008=C2 domain, IPR001478=PDZ domain" CG43955 16-Dec-15 2015_12 ENSDARG00000035994(LOC563393) "ENSXETG00000017630(RIMS3),ENSXETG00000026456(RIMS2),ENSXETG00000022829(RIMS4)" "ENSMUSG00000035226(Rims4),ENSMUSG00000032890(Rims3)" "ENSG00000101098(RIMS4),ENSG00000117016(RIMS3)" FBgn0028956 mthl3 methuselah-like 3 http://flybase.net/reports/FBgn0028956.html "FBgn0034220, FBgn0046526, FBgn0046527" protein_coding_gene 0004930=G-protein coupled receptor activity "0042594=response to starvation, 0007186=G-protein coupled receptor signaling pathway, 0008340=determination of adult lifespan" 0016021=integral component of membrane "Mth-like 3, 104/8, anon-WO0170980.52, unnamed, CG6530, mth-like 3, gene 1, Mth-3, mthl-3, anon-WO0170980.53, BEST:GM02553, GENE 1, l(2)k10408" "IPR023311=Methuselah ectodomain, domain 2, IPR010596=Methuselah, N-terminal domain, IPR000832=GPCR, family 2, secretin-like, IPR017981=GPCR, family 2-like" CG6530 16-Dec-15 2015_12 ENSDARG00000034975(gpr157) "ENSXETG00000028017(),ENSXETG00000020592(),ENSXETG00000020611(),ENSXETG00000020575(),ENSXETG00000020610(CD97),ENSXETG00000009348(GPR133)" "viable,fertile" DRSC06997 K 1.394041873 -0.533985869 -0.357090399 -0.23893153 2.185723118 0.515978973 FBgn0038013 CG10038 http://flybase.net/reports/FBgn0038013.html protein_coding_gene "IPR029058=Alpha/Beta hydrolase fold, IPR019154=Arb2 domain" CG10038 16-Dec-15 2015_12 ENSDARG00000058982(LOC100331449) WBGene00013561(Y75B8A.31) ENSXETG00000011592(Q6DIP8_XENTR) ENSMUSG00000064138(Fam172a) "ENSG00000113391(FAM172A),ENSG00000175841" "viable,fertile" FBgn0033423 CG1809 http://flybase.net/reports/FBgn0033423.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR017850=Alkaline-phosphatase-like, core domain, IPR018299=Alkaline phosphatase, active site, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha, IPR001952=Alkaline phosphatase" CG1809 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSMUSG00000028766(Alpl),ENSMUSG00000026246(Alppl2),ENSMUSG00000079440(Alpi),ENSMUSG00000036500(Akp3)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" viable FBgn0053532 lectin-37Da lectin-37Da http://flybase.net/reports/FBgn0053532.html "FBgn0032778, FBgn0040095, FBtr0081202, FBpp0080743" protein_coding_gene 0005534=galactose binding 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 0005576=extracellular region "AC 007082B, CG9978, Drosophila lectin 2, DL2, lectin, AC007082b, CG33532" "IPR016187=C-type lectin fold, IPR001304=C-type lectin, IPR016186=C-type lectin-like" CG33532 16-Dec-15 2015_12 "ENSDARG00000059261(LOC100333431),ENSDARG00000068178,ENSDARG00000012263(si:ch73-343l4.8),ENSDARG00000071218,ENSDARG00000025547,ENSDARG00000071219(illr2),ENSDARG00000059254(illr1),ENSDARG00000018327(illr3),ENSDARG00000025150,ENSDARG00000069322,ENSDARG00000043894,ENSDARG00000055817,ENSDARG00000029461,ENSDARG00000057091,ENSDARG00000045511,ENSDARG00000008182,ENSDARG00000032346,ENSDARG00000039636,ENSDARG00000069323,ENSDARG00000069226,ENSDARG00000026805,ENSDARG00000057090,ENSDARG00000057092,ENSDARG00000042136,ENSDARG00000070106(LOC100331932)" "ENSXETG00000000644(),ENSXETG00000021878(),ENSXETG00000000646(),ENSXETG00000026809(),ENSXETG00000023911()" "ENSMUSG00000040197(Cd209e),ENSMUSG00000040165(Cd209c),ENSMUSG00000031494(Cd209a),ENSMUSG00000065987(Cd209b),ENSMUSG00000079168(Cd209g),ENSMUSG00000074491(Clec4g),ENSMUSG00000030142(Clec4e),ENSMUSG00000051906(Cd209f),ENSMUSG00000071158(Gm156),ENSMUSG00000030158(Clec12b)" "ENSG00000166527(CLEC4D),ENSG00000205846(CLEC6A),ENSG00000166523(CLEC4E),ENSG00000141505(ASGR1)" FBgn0038588 CG7156 http://flybase.net/reports/FBgn0038588.html protein_coding_gene "0035091=phosphatidylinositol binding, 0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0006468=protein phosphorylation, 0048812=neuron projection morphogenesis" "IPR001683=Phox homologous domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR007330=MIT" CG7156 16-Dec-15 2015_12 WBGene00010096(rskd-1) ENSXETG00000013263(RPS6KL1) ENSMUSG00000037581(Rps6kc1) "ENSG00000136643(RPS6KC1),ENSG00000198208(RPS6KL1)" viable FBgn0262601 SmB Small ribonucleoprotein particle protein SmB http://flybase.net/reports/FBgn0262601.html "FBgn0010083, FBgn0065747" protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome, 0007281=germ cell development, 0008406=gonad development, 0007052=mitotic spindle organization, 0016070=RNA metabolic process" "0005681=spliceosomal complex, 0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0045495=pole plasm, 0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0015030=Cajal body" "Sm B, l(2)SH0509, SmB1, snRNP B, B, lethal (2) SH0509, SYM10, l(2)SH2 0509, polypeptide B, Small ribonucleoprotein particle protein B, dSmB, CG5352" "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type" CG5352 16-Dec-15 2015_12 ENSDARG00000011125 WBGene00004915(snr-2) ENSXETG00000027266(snrpb) "ENSMUSG00000027404(Snrpb),ENSMUSG00000000948(Snurf)" "ENSG00000125835(SNRPB),ENSG00000128739(SNRPN)" DRSC03437 IEK -1.681650757 1.349981291 -0.785851337 -2.035756428 -0.158033788 2.025258392 FBgn0002873 mud mushroom body defect http://flybase.net/reports/FBgn0002873.html "FBgn0052599, FBgn0030557" protein_coding_gene "0003677=DNA binding, 0005515=protein binding" "0034454=microtubule anchoring at centrosome, 0040040=thermosensory behavior, 0016319=mushroom body development, 0007058=spindle assembly involved in female meiosis II, 0000132=establishment of mitotic spindle orientation, 0055059=asymmetric neuroblast division" "0005938=cell cortex, 0005875=microtubule associated complex, 0045180=basal cortex, 0051233=spindle midzone, 0005813=centrosome, 0045179=apical cortex, 0005819=spindle" "Mushroom Body Defect, CG12047, Mushroom body defect, mushroom bodies deranged, Mud, KS63, mushroom body defective, NuMA" CG12047 16-Dec-15 2015_12 ENSG00000096696(DSP) " embryonic stage , larval stage , adult stage , larval stage | male " "partially lethal - majority die,female sterile,lethal,female,male fertile,wild-type,chemical sensitive,codominant,female limited,locomotor behavior defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage,sterile" "embryonic neuroblast,macrochaeta,Kenyon cell,adult mushroom body,vertical branch of mushroom body,adult central complex,egg,maternal effect,egg & chromatin | maternal effect,egg & spindle | maternal effect,calyx of adult mushroom body,medial lobe of adult mushroom body,lobe system of adult mushroom body,neuroblast,supernumerary,spindle,somatic clone,ganglion mother cell,neuropil,antennal lobe,centrosome,embryonic/larval neuroblast,astral microtubule,abdominal 2 ventro-medial neuroblast,abdominal 3 ventro-medial neuroblast,abdominal 4 ventro-medial neuroblast,abdominal 5 ventro-medial neuroblast,abdominal 6 ventro-medial neuroblast,abdominal 7 ventro-medial neuroblast,abdominal 2 dorso-lateral neuroblast,abdominal 3 dorso-lateral neuroblast,abdominal 4 dorso-lateral neuroblast,abdominal 5 dorso-lateral neuroblast,abdominal 6 dorso-lateral neuroblast,abdominal 7 dorso-lateral neuroblast,mushroom body pedunculus" FBgn0034527 CG9945 http://flybase.net/reports/FBgn0034527.html protein_coding_gene 0005875=microtubule associated complex "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR017399=WD repeat protein DCAF11/LEC14B" CG9945 16-Dec-15 2015_12 ENSDARG00000009868(dcaf11) WBGene00008419(wdr-23) ENSXETG00000014610(wdr23) ENSMUSG00000022214(Dcaf11) ENSG00000100897(DCAF11) viable FBgn0259994 CG42492 http://flybase.net/reports/FBgn0259994.html "FBgn0029779, FBgn0044695, FBgn0040914" protein_coding_gene "CG11473, anon-WO0140519.181, CG17761" IPR004878=Otopetrin CG42492 16-Dec-15 2015_12 ENSDARG00000006522(otop2) "WBGene00018478(otpl-5),WBGene00017034(otpl-2),WBGene00018479(otpl-6),WBGene00018480(otpl-7),WBGene00010403(otpl-8)" "ENSXETG00000006849(),ENSXETG00000016028(OTOP1),ENSXETG00000027433(),ENSXETG00000012496(),ENSXETG00000006252(),ENSXETG00000027068()" "ENSMUSG00000050201(Otop2),ENSMUSG00000018862(Otop3),ENSMUSG00000051596(Otop1)" "ENSG00000183034(OTOP2),ENSG00000182938(OTOP3)" FBgn0034494 CG10444 http://flybase.net/reports/FBgn0034494.html protein_coding_gene 0008523=sodium-dependent multivitamin transmembrane transporter activity 0055085=transmembrane transport 0016020=membrane dSLC5A3 "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG10444 16-Dec-15 2015_12 "ENSDARG00000042859(si:dkey-5g7.3),ENSDARG00000014599(zgc:114067),ENSDARG00000003697(slc5a8l),ENSDARG00000005004" YHL016C(DUR3) WBGene00014092(ZK822.5) "ENSXETG00000025601(SLC5A12),ENSXETG00000013546(SLC5A5),ENSXETG00000002542(slc5a8)" "ENSMUSG00000020062(Slc5a8),ENSMUSG00000041644(Slc5a12),ENSMUSG00000000792(Slc5a5),ENSMUSG00000006641(Slc5a6)" "ENSG00000139357,ENSG00000148942(SLC5A12),ENSG00000105641(SLC5A5),ENSG00000138074(SLC5A6)" "lethal,viable,fertile" FBgn0031470 CG18557 http://flybase.net/reports/FBgn0031470.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis c-SPH125 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG18557 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" viable FBgn0013773 Cyp6a22 Cyp6a22 http://flybase.net/reports/FBgn0013773.html FBgn0033976 protein_coding_gene "0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "Cytochrome P450 related BF6-2, 6a22, cyp6a22, BF6-2, P450, Cyt-P450-rBF6-2, P-450, cytochrome P450, CG10240" "IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site" CG10240 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0259108 futsch futsch http://flybase.net/reports/FBgn0259108.html "FBgn0015390, FBgn0029577, FBgn0085416, FBgn0029578, FBgn0025392, FBgn0243483" protein_coding_gene "0005515=protein binding, 0008017=microtubule binding" "0008582=regulation of synaptic growth at neuromuscular junction, 0000226=microtubule cytoskeleton organization, 0007399=nervous system development, 0008355=olfactory learning, 0007409=axonogenesis, 0048813=dendrite morphogenesis, 0007017=microtubule-based process, 0007528=neuromuscular junction development, 0060052=neurofilament cytoskeleton organization, 0008088=axon cargo transport, 0043524=negative regulation of neuron apoptotic process, 1901215=negative regulation of neuron death, 0048749=compound eye development" "0043025=neuronal cell body, 0030425=dendrite, 0030424=axon, 0005875=microtubule associated complex, 0015630=microtubule cytoskeleton, 0005874=microtubule" "MAP1B, 22C20, mAb-22C10, Mab 22C10, MAb22C10, Map1B, Futsch, Mab22C10, 22c10, MAP-IB, CG3064, FUTSCH, map1b, Map-1B, Futch, CG14772, ssC10, Mab22c10, CG34387, Olk, 22C10, EG:49E4.1, 22C10/FUTSCH, olk, mAb 22C10, mAb22C10, mAb22c10, omb-like, lincRNA.936" "IPR026074=Microtubule associated protein 1, IPR009603=Microtubule associated protein Futsch" CG34387 16-Dec-15 2015_12 "ENSMUSG00000027254(Mtap1a),ENSMUSG00000052727(Mtap1b)" "ENSG00000166963(MAP1A),ENSG00000131711(MAP1B)" FBgn0035356 CG16986 http://flybase.net/reports/FBgn0035356.html protein_coding_gene 0047617=acyl-CoA hydrolase activity 0051289=protein homotetramerization "IPR006683=Thioesterase superfamily, IPR029069=HotDog domain, IPR003736=Phenylacetic acid degradation-related domain" CG16986 16-Dec-15 2015_12 ENSDARG00000061728(acot13) "WBGene00016112(C25H3.3),WBGene00016123(C25H3.14)" ENSXETG00000025940(Q6DER5_XENTR) ENSMUSG00000006717(Acot13) ENSG00000112304(ACOT13) "viable,fertile" DRSC08502 E -0.188418959 0.875263803 1.521510357 0.896382162 0.525447332 -1.079536714 FBgn0050000 GstT1 Glutathione S transferase T1 http://flybase.net/reports/FBgn0050000.html "FBgn0033436, FBgn0047071" protein_coding_gene 0004364=glutathione transferase activity 0006749=glutathione metabolic process 0005737=cytoplasm "gstt1, CG12930, BcDNA:RE63575, GSTT1, CG12930B, CG30000" "IPR004046=Glutathione S-transferase, C-terminal, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like" CG30000 16-Dec-15 2015_12 "ENSDARG00000042428(gstt1a),ENSDARG00000017388(gstt1b)" "ENSMUSG00000001663(Gstt1),ENSMUSG00000001665(Gstt3),ENSMUSG00000009093(Gstt4),ENSMUSG00000033318(Gstt2)" viable FBgn0021761 Nup154 Nucleoporin 154kD http://flybase.net/reports/FBgn0021761.html "FBgn0010493, FBgn0016083, FBgn0027862" protein_coding_gene "0003682=chromatin binding, 0005515=protein binding, 0017056=structural constituent of nuclear pore" "0006913=nucleocytoplasmic transport, 0036228=protein targeting to nuclear inner membrane" "0005737=cytoplasm, 0005634=nucleus, 0005635=nuclear envelope, 0005643=nuclear pore" "zonder kloten, tip, zk, Nup32D, l(2)10432, ms(2)zk, Nucleoporin 154, Nup154, Nup155, nup32D, BcDNA:LD21772, CG4579, tlp, nup154, tulipano, Nup, l(2)01501" "IPR004870=Nucleoporin, Nup155-like, IPR014908=Nucleoporin, Nup133/Nup155-like, N-terminal, IPR007187=Nucleoporin, Nup133/Nup155-like, C-terminal" CG4579 16-Dec-15 2015_12 ENSDARG00000001777(nup155) "YBL079W(NUP170),YER105C(NUP157)" WBGene00003794(npp-8) ENSXETG00000004785(NUP155) ENSMUSG00000022142(Nup155) ENSG00000113569(NUP155) " embryonic stage | stage >=11 , embryonic stage | stage 8-9 , embryonic stage | stage 16-17 , embryonic stage&&larval stage&&adult stage , embryonic stage | 0-2hr , embryonic stage | stage 14 , embryonic stage | stage 16,17 , larval stage , adult stage && oogenesis stage , embryonic stage | stage 5-9 , adult stage | male " " embryonic/larval midgut

, mesoderm

, germline cell

, embryonic/larval hindgut

,

ubiquitous , embryonic/larval dorsal vessel

, lymph gland

, imaginal disc

, egg chamber

, embryonic brain | restricted

, germarium

, embryonic/larval foregut

, pole cell | vicinity of

, embryonic central nervous system

, embryonic brain

, testis

, larval brain | restricted

" adult stage && oogenesis stage " germarium

, spermatocyte

, oocyte

, egg chamber

" "male fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,male sterile,female sterile,recessive,viable,lethal,female semi-sterile,female fertile,wild-type,partially lethal - majority die,visible,cell growth defective" "testis,ovary,germline cell,male,egg chamber,embryonic/larval brain,embryonic/larval optic lobe,imaginal disc,embryonic/larval lymph gland,spermatid,meiotic cell cycle | male,ovariole,egg,dorsal appendage,follicle cell,oocyte,nurse cell,testis & meiotic cell cycle,cyst cell,cyst cell & spindle,spermatid axoneme,spermatocyte,spermatocyte & nuclear membrane,nurse cell & chromatin,embryonic/larval hemocyte,mesothoracic tergum" FBgn0026315 Ugt35a UDP-glycosyltransferase 35a http://flybase.net/reports/FBgn0026315.html "FBgn0015835, FBgn0040254" protein_coding_gene "0016758=transferase activity, transferring hexosyl groups, 0008194=UDP-glycosyltransferase activity" 0006011=UDP-glucose metabolic process 0016021=integral component of membrane "ugt35a, DmeUgt35a, UDPGT1, AC 006491F, Ugt86Df, unnamed, CG6644" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG6644 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00010904(ugt-62),WBGene00018206(ugt-61)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" adult stage " leg

, antennal segment 3

" FBgn0052750 CG32750 http://flybase.net/reports/FBgn0052750.html FBgn0029847 protein_coding_gene "0016811=hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" 0006807=nitrogen compound metabolic process "CG3648, Pantetheine hydrolase" "IPR003010=Carbon-nitrogen hydrolase, IPR012101=Biotinidase, eukaryotic" CG32750 16-Dec-15 2015_12 ENSDARG00000006926 "ENSXETG00000000104(BC087969.1),ENSXETG00000008991(BTD)" "ENSMUSG00000021900(Btd),ENSMUSG00000037440(Vnn1),ENSMUSG00000020010(Vnn3)" "ENSG00000169814(BTD),ENSG00000112299(VNN1),ENSG00000112303(VNN2),ENSG00000093134" FBgn0030449 Fer3HCH Ferritin 3 heavy chain homologue http://flybase.net/reports/FBgn0030449.html protein_coding_gene "0008199=ferric iron binding, 0008198=ferrous iron binding" "0010106=cellular response to iron ion starvation, 0006826=iron ion transport, 0046427=positive regulation of JAK-STAT cascade, 0006879=cellular iron ion homeostasis" 0008043=intracellular ferritin complex "mitoch. ferritin, CG4349" "IPR014034=Ferritin, conserved site, IPR009040=Ferritin- like diiron domain, IPR008331=Ferritin/DPS protein domain, IPR001519=Ferritin, IPR012347=Ferritin-related, IPR009078=Ferritin-like superfamily" CG4349 16-Dec-15 2015_12 "ENSDARG00000031776(zgc:92066),ENSDARG00000024414,ENSDARG00000037936(zgc:109934),ENSDARG00000054192,ENSDARG00000054197,ENSDARG00000033880,ENSDARG00000054178,ENSDARG00000015551(fth1),ENSDARG00000007975(zgc:92245),ENSDARG00000018461(zgc:56095)" "WBGene00001501(ftn-2),WBGene00001500(ftn-1)" "ENSXETG00000021236(BC061303.1),ENSXETG00000021234(BC076689.1),ENSXETG00000006737(fth1),ENSXETG00000021237(BC063337.1),ENSXETG00000021235(BC062508.1)" "ENSMUSG00000024510(Ftmt),ENSMUSG00000024661(Fth1),ENSMUSG00000071815(Gm14511),ENSMUSG00000078208(Gm5634),ENSMUSG00000050708(Ftl1),ENSMUSG00000062382(Gm10116),ENSMUSG00000072249(Gm5635),ENSMUSG00000060685(Fthl17),ENSMUSG00000078206(Gm14458),ENSMUSG00000057829(Gm5278),ENSMUSG00000035491(1600014K23Rik)" "ENSG00000181867(FTMT),ENSG00000167996(FTH1),ENSG00000219186,ENSG00000132446(FTHL17),ENSG00000087086(FTL)" viable DRSC19892 K -0.811924654 0.202152782 -0.017299349 0.189199491 1.516577578 0.123062004 FBgn0036376 Liprin-ë_ Liprin-ë_ http://flybase.net/reports/FBgn0036376.html protein_coding_gene "0005515=protein binding, 0042803=protein homodimerization activity" "0051124=synaptic growth at neuromuscular junction, 0007412=axon target recognition" 0043234=protein complex "Liprin-beta, CG10743" "IPR030444=Liprin-beta, IPR001660=Sterile alpha motif domain, IPR029515=LAR-interacting protein, Liprin, IPR013761=Sterile alpha motif/pointed domain" CG10743 16-Dec-15 2015_12 "ENSDARG00000020236(si:dkey-103i16.1),ENSDARG00000029168,ENSDARG00000061977(LOC565051),ENSDARG00000045749(si:dkey-207j16.2)" WBGene00011904(hlb-1) "ENSXETG00000016522(PPFIBP1),ENSXETG00000009056(TGas021d03.1)" "ENSMUSG00000016487(Ppfibp1),ENSMUSG00000036528(Ppfibp2)" "ENSG00000110841(PPFIBP1),ENSG00000166387(PPFIBP2)" "neuroanatomy defective,partially lethal - majority die,recessive,viable" "photoreceptor cell R7,medulla,NMJ bouton" FBgn0034261 HPS4 Hermansky-Pudlak Syndrome 4 ortholog (H. sapiens) http://flybase.net/reports/FBgn0034261.html protein_coding_gene "0060967=negative regulation of gene silencing by RNA, 0035280=miRNA loading onto RISC involved in gene silencing by miRNA, 0070923=siRNA loading onto RISC involved in chromatin silencing by small RNA" "0031902=late endosome membrane, 0005765=lysosomal membrane, 0031085=BLOC-3 complex" "dHPS4, NP_725707, Hermansky-Pudlak Syndrome 4 ortholog, CG4966" IPR026091=Hermansky-Pudlak syndrome 4 protein CG4966 16-Dec-15 2015_12 ENSDARG00000013795(zgc:56538) ENSMUSG00000042328(Hps4) ENSG00000100099(HPS4) "viable,fertile" DRSC06906 E 0.440450544 -0.065199931 -2.081890088 0.704641029 0.513030281 -0.007097266 FBgn0259168 mnb minibrain http://flybase.net/reports/FBgn0259168.html "FBgn0002777, FBgn0030879" protein_coding_gene "0005524=ATP binding, 0004712=protein serine/threonine/tyrosine kinase activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0035332=positive regulation of hippo signaling, 0007420=brain development, 0007611=learning or memory, 2000253=positive regulation of feeding behavior, 0045927=positive regulation of growth, 0008355=olfactory learning, 0007399=nervous system development, 1900244=positive regulation of synaptic vesicle endocytosis, 0007623=circadian rhythm, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0006468=protein phosphorylation, 0007632=visual behavior" 0043195=terminal bouton "Dyrk1, Mnb, unnamed, CG7835, ME-IV, Dyrk1A, minibrain, DmDyrk1A, Dm1, CG42273, MNB, Minibrain kinase, min, Dual-specificity tyrosine phosphorylation-regulated kinase 1A, CG7826, Minibrain, DYRK1" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG42273 16-Dec-15 2015_12 "ENSDARG00000009984,ENSDARG00000023814(dyrk1ab),ENSDARG00000063570(dyrk1aa),ENSDARG00000070187" ENSXETG00000013037(DYRK1A) embryonic stage " supraesophageal ganglion

, ventral nerve cord

" " embryonic stage -- adult stage , larval stage , adult stage , larval stage && pupal stage " " mushroom body

, larval outer optic anlage

, mushroom body gamma-lobe

, retina

, pigment cell

, mushroom body beta-lobe

, larval optic lobe

" FBgn0039201 CG13617 http://flybase.net/reports/FBgn0039201.html protein_coding_gene 0046872=metal ion binding "Iguana, Dzip1" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG13617 16-Dec-15 2015_12 ENSDARG00000038245(zgc:123017) ENSXETG00000022691(DZIP1L) "ENSMUSG00000037784(Dzip1l),ENSMUSG00000042156(Dzip1)" "ENSG00000134874(DZIP1),ENSG00000158163(DZIP1L)" viable FBgn0053813 His1:CG33813 His1:CG33813 http://flybase.net/reports/FBgn0053813.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33813 "IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain" CG33813 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0019932 SamDC S-adenosylmethionine decarboxylase http://flybase.net/reports/FBgn0019932.html "FBgn0014220, FBgn0014221, FBgn0014222, FBgn0024936" protein_coding_gene 0004014=adenosylmethionine decarboxylase activity "0006597=spermine biosynthetic process, 0050829=defense response to Gram-negative bacterium, 0008295=spermidine biosynthetic process" "l(2)31De, l(2)31Dd, S-adenosyl decarboxylase, l(2)31Dc, CG5029" "IPR018167=S-adenosylmethionine decarboxylase subgroup, IPR016067=S-adenosylmethionine decarboxylase, core, IPR001985=S-adenosylmethionine decarboxylase, IPR018166=S-adenosylmethionine decarboxylase, conserved site" CG5029 16-Dec-15 2015_12 ENSDARG00000043856(amd1) YOL052C(SPE2) WBGene00004875(smd-1) ENSXETG00000021331(AMD1) "ENSMUSG00000063953(Amd2),ENSMUSG00000075232(Amd1),ENSMUSG00000060096(Amd-ps3)" ENSG00000123505(AMD1) embryonic stage -- adult stage "lethal,recessive,visible,viable" macrochaeta DRSC03429 I 1.919139436 1.266253248 -0.496320004 1.333449635 -0.538493908 0.158053736 FBgn0035944 CG5021 http://flybase.net/reports/FBgn0035944.html protein_coding_gene 0016021=integral component of membrane "IPR008564=Protein of unknown function DUF846, eukaryotic" CG5021 16-Dec-15 2015_12 "ENSDARG00000057060(zgc:110017),ENSDARG00000001804(zgc:112148)" YDR084C(TVP23) WBGene00016400(C34D4.4) "ENSXETG00000007989(FAM18A),ENSXETG00000019575(Q6DES5_XENTR)" "ENSMUSG00000050908(Fam18a),ENSMUSG00000014177(Fam18b)" "ENSG00000166676(FAM18A),ENSG00000171928(FAM18B1)" "viable,visible" "trichogen cell,supernumerary" FBgn0004430 LysS Lysozyme S http://flybase.net/reports/FBgn0004430.html "FBgn0002575, FBgn0063108" protein_coding_gene 0003796=lysozyme activity 0019730=antimicrobial humoral response "lysozyme S, CG1165, lysS, BcDNA:LP06719" "IPR001916=Glycoside hydrolase, family 22, IPR023346=Lysozyme-like domain, IPR019799=Glycoside hydrolase, family 22, conserved site, IPR000974=Glycoside hydrolase, family 22, lysozyme" CG1165 16-Dec-15 2015_12 "ENSXETG00000026780(LYZ),ENSXETG00000013041(),ENSXETG00000018647(BC075444.1)" "ENSMUSG00000069515(Lyz1),ENSMUSG00000069516(Lyz2),ENSMUSG00000020177(9530003J23Rik),ENSMUSG00000024233(Lyzl1),ENSMUSG00000053184(Spaca3),ENSMUSG00000037167(Spaca5),ENSMUSG00000020945(Lyzl6)" ENSG00000090382(LYZ) larval stage gastric caecum

viable FBgn0053804 His1:CG33804 His1:CG33804 http://flybase.net/reports/FBgn0053804.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33804 "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5" CG33804 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0032516 CG9293 http://flybase.net/reports/FBgn0032516.html protein_coding_gene 0008270=zinc ion binding "0008285=negative regulation of cell proliferation, 0016573=histone acetylation" 0070776=MOZ/MORF histone acetyltransferase complex "IPR028638=Inhibitor of growth protein 5, IPR001965=Zinc finger, PHD-type, IPR019787=Zinc finger, PHD-finger, IPR024610=Inhibitor of growth protein, N-terminal histone-binding, IPR028651=ING family, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG9293 16-Dec-15 2015_12 "ENSDARG00000022413(ing5),ENSDARG00000068175(ing5b),ENSDARG00000030716(ing4)" "YHR090C(YNG2),YNL097C(PHO23)" WBGene00020287(T06A10.4) ENSXETG00000002976(ing5) "ENSMUSG00000030330(Ing4),ENSMUSG00000026283(Ing5)" "ENSG00000215693,ENSG00000168395(ING5),ENSG00000111653(ING4)" "viable,fertile" DRSC03188 I -1.015864702 -2.5650718 0.061734833 1.255705451 0.268726134 0.429755172 FBgn0039378 ë±4GT2 ë±4GT2 http://flybase.net/reports/FBgn0039378.html protein_coding_gene "0035248=alpha-1,4-N-acetylgalactosaminyltransferase activity, 0008378=galactosyltransferase activity" 0006688=glycosphingolipid biosynthetic process 0016020=membrane "alpha4GT2, CG5878" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR007577=Glycosyltransferase, DXD sugar-binding motif, IPR007652=Alpha 1,4-glycosyltransferase domain" CG5878 16-Dec-15 2015_12 "ENSXETG00000027419(A4GALT),ENSXETG00000022707(),ENSXETG00000022706(),ENSXETG00000004687(),ENSXETG00000008304(),ENSXETG00000005012(),ENSXETG00000024912()" "ENSMUSG00000047878(A4galt),ENSMUSG00000037953(A4gnt)" "ENSG00000128274,ENSG00000118017(A4GNT)" FBgn0040255 Ugt86De Ugt86De http://flybase.net/reports/FBgn0040255.html FBgn0037867 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG6653, AC 006491E, Ugt86DE, CG6653-PA" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG6653 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0001092 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2 http://flybase.net/reports/FBgn0001092.html protein_coding_gene "0050661=NADP binding, 0051287=NAD binding, 0004365=glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity" "0006096=glycolytic process, 0055114=oxidation-reduction process, 0006006=glucose metabolic process" "0005875=microtubule associated complex, 0005737=cytoplasm, 0005811=lipid particle" "Glyceraldehyde-3-phosphate dehydrogenase, G3-P dehydrogenase, GAPDH II, Gapdh13F, GAPDH2, GADPH, glyceraldehyde 3-phosphate dehydrogenase, GAPDH, Gapd, CG8893, GAP, glyceraldehyde-3-phosphate dehydrogenase, Gapdh-2, GA3PDH, Gapdh" "IPR006424=Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020830=Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR020829=Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR020831=Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR020828=Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR016040=NAD(P)-binding domain" CG8893 16-Dec-15 2015_12 ENSDARG00000043457(gapdh) "YGR192C(TDH3),YJL052W(TDH1),YJR009C(TDH2)" "WBGene00001685(gpd-3),WBGene00001684(gpd-2),WBGene00001683(gpd-1),WBGene00001686(gpd-4)" "ENSMUSG00000079501(Gm5138),ENSMUSG00000078965(Gm12033),ENSMUSG00000078162(Gm2574),ENSMUSG00000078967(Gm3272),ENSMUSG00000078088,ENSMUSG00000078142,ENSMUSG00000057666(Gapdh),ENSMUSG00000078592(Gm4609),ENSMUSG00000078191(Gm5559),ENSMUSG00000078300(Gm2606),ENSMUSG00000079360(Gm3839),ENSMUSG00000078573(Gm2451),ENSMUSG00000073212(Gm10481),ENSMUSG00000070025(Gm10284),ENSMUSG00000070490(Gm10293),ENSMUSG00000078636(Gm3200),ENSMUSG00000071813(Gm16374),ENSMUSG00000070443(Gm10291),ENSMUSG00000070408(Gm10290),ENSMUSG00000078370(Gm6316),ENSMUSG00000055676,ENSMUSG00000078308(Gm7293),ENSMUSG00000079558(Gm6981),ENSMUSG00000069236" ENSG00000111640(GAPDH) adult stage "viable,fertile" FBgn0011829 Ret Ret oncogene http://flybase.net/reports/FBgn0011829.html "FBgn0022789, FBgn0032930, FBgn0032931" protein_coding_gene "0005509=calcium ion binding, 0005524=ATP binding, 0005178=integrin binding, 0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity" "0016358=dendrite development, 0007165=signal transduction, 0007015=actin filament organization, 0001954=positive regulation of cell-matrix adhesion, 0006468=protein phosphorylation" "0009986=cell surface, 0005887=integral component of plasma membrane, 0005886=plasma membrane, 0030425=dendrite" "DRet, Dret, dRet, CG1061, ret, DmRet, DRET, RET, HD-59, D-ret, Reto, MEN2, dRET, DmHD-59, CG14396, dret" "IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG14396 16-Dec-15 2015_12 ENSDARG00000055305(ret1) ENSMUSG00000030110(Ret) ENSG00000165731(RET) " embryonic stage | stage >=12 , embryonic stage | stage 12 , embryonic stage | stage 11-12 , embryonic stage | stage 16 , embryonic stage | late , embryonic stage | stage 13 , embryonic stage | stage 8-11 , embryonic stage | stage >=13 , embryonic stage | cellular blastoderm , larval stage , pupal stage , embryonic stage , adult stage && oogenesis stage , larval stage | third instar " " embryonic brain | restricted

, anterior midgut proper primordium

, neuroblast | subset

, posterior midgut proper primordium

, embryonic proventricular ganglion

, larval labral segment sense organ | precursor

, dorsal organ | precursor

, embryonic peripheral nervous system | restricted

, yolk sac

, embryonic frontal ganglion

, ventral nerve cord | restricted

, labral nerve | precursor

, terminal organ | precursor

, midgut imaginal island

, embryonic esophageal ganglion

,

restricted , Bolwig's organ

, nurse cell

, embryonic stomatogastric nervous system

, eye disc | restricted

, embryonic Malpighian tubule

" "visible,partially lethal - majority die,decreased cell death,viable,size defective,lethal - all die before end of pupal stage,somatic clone,lethal,heat sensitive" "eye,ommatidium,eye disc,cone cell,wing vein,anterior crossvein,genital arch,wing disc,retina,supernumerary,inter-ommatidial cell,trichogen cell,scutellum | pupal stage,mesothoracic tergum,somatic clone,wing,ectopic,indirect flight muscle" FBgn0039669 ND-20L NADH dehydrogenase (ubiquinone) 20 kDa subunit-like http://flybase.net/reports/FBgn0039669.html protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0051539=4 iron, 4 sulfur cluster binding, 0048038=quinone binding, 0003954=NADH dehydrogenase activity" "0002121=inter-male aggressive behavior, 0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NUKM, ND20-like, CG2014, NADH: ubiquinone oxidoreductase-like, 20kDa subunit, NADH:ubiquinone oxidoreductase 20 kDa subunit, NADH-ubiquinone oxidoreductase 20 kDa subunit" "IPR006137=NADH:ubiquinone oxidoreductase-like, 20kDa subunit, IPR006138=NADH-ubiquinone oxidoreductase, 20 Kd subunit" CG2014 16-Dec-15 2015_12 WBGene00012376(nduf-7) ENSXETG00000003702() ENSMUSG00000020153(Ndufs7) viable FBgn0042103 CG18746 http://flybase.net/reports/FBgn0042103.html protein_coding_gene "IPR011021=Arrestin-like, N-terminal, IPR014756=Immunoglobulin E-set, IPR011022=Arrestin C-terminal-like domain" CG18746 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" WBGene00011732(T12D8.4) "ENSXETG00000013606(ARRDC2),ENSXETG00000018085(arrdc3),ENSXETG00000002108(ARRDC4),ENSXETG00000011050(TXNIP)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" "ENSG00000105643(ARRDC2),ENSG00000113369(ARRDC3),ENSG00000140450(ARRDC4),ENSG00000117289(TXNIP)" viable FBgn0035042 CG3640 http://flybase.net/reports/FBgn0035042.html protein_coding_gene 0032504=multicellular organism reproduction 0005576=extracellular region "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG3640 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0039129 RpS19b Ribosomal protein S19b http://flybase.net/reports/FBgn0039129.html FBgn0062857 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0022627=cytosolic small ribosomal subunit "RpS19, Ribosomal protein S19, CG5338, BcDNA:SD22440" "IPR018277=Ribosomal protein S19e, conserved site, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001266=Ribosomal protein S19e" CG5338 16-Dec-15 2015_12 ENSDARG00000030602(rps19) "YOL121C(RPS19A),YNL302C(RPS19B)" WBGene00004488(rps-19) ENSXETG00000025510(RPS19) "ENSMUSG00000040952(Rps19),ENSMUSG00000072528(Gm6636),ENSMUSG00000072548(Rps19-ps2),ENSMUSG00000069391(Gm4838)" ENSG00000105372(RPS19) "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0010019 Cyp4g1 Cytochrome P450-4g1 http://flybase.net/reports/FBgn0010019.html "FBgn0011757, FBgn0023539, FBgn0044782" protein_coding_gene "0005506=iron ion binding, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity" "0006629=lipid metabolic process, 0055114=oxidation-reduction process" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "Cytochrome P450 A1, P450, P-450-A, 4g1, EG:165H7.1, P450A, scgamma, P450-A, CG3972, cytochrome P450, ASC-T1, cyp4g1, Achaete-scute Complex transcript 1, P-450, CYP4G1, T1, Cytochrome P450 4g1, anon-WO0140519.102, Cyt-P450-A1" "IPR002401=Cytochrome P450, E-class, group I, IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450" CG3972 16-Dec-15 2015_12 YMR015C(ERG5) "lethal - all die before end of pupal stage,recessive,some die during pupal stage,viable" FBgn0039274 CG11920 http://flybase.net/reports/FBgn0039274.html protein_coding_gene 0009267=cellular response to starvation "0005654=nucleoplasm, 0005730=nucleolus, 0030532=small nuclear ribonucleoprotein complex" "IPR007109=Brix domain, IPR004154=Anticodon-binding" CG11920 16-Dec-15 2015_12 ENSDARG00000054540(imp4) YNL075W(IMP4) WBGene00014083(ZK795.3) ENSXETG00000016795(imp4) ENSMUSG00000026127(Imp4) ENSG00000136718(IMP4) FBgn0013770 Cp1 Cysteine proteinase-1 http://flybase.net/reports/FBgn0013770.html FBgn0019814 protein_coding_gene "0004197=cysteine-type endopeptidase activity, 0008233=peptidase activity" "0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0030163=protein catabolic process, 0006508=proteolysis" "0045169=fusome, 0005764=lysosome" "cysteine proteinase-1, Dcp1, CysP-1, CL, CG6692, Drosophila Cysteine proteinase-1, fs(2)50Ca, CTSL, cathepsin L, cysteine proteinase 1, DCP1, Cath L, Cathepsin L, CT20780, CatL, CP1, CATL_DROME, Dcp-1, unnamed, cp1, L-like cysteine protease" "IPR013201=Cathepsin propeptide inhibitor domain (I29), IPR000169=Cysteine peptidase, cysteine active site, IPR013128=Peptidase C1A, IPR025661=Cysteine peptidase, asparagine active site, IPR000668=Peptidase C1A, papain C-terminal, IPR025660=Cysteine peptidase, histidine active site" CG6692 16-Dec-15 2015_12 "ENSDARG00000007836(ctsl1a),ENSDARG00000011701(ctsll),ENSDARG00000056747,ENSDARG00000071634,ENSDARG00000071631,ENSDARG00000039173(ctsl1b),ENSDARG00000056692,ENSDARG00000071635,ENSDARG00000045187,ENSDARG00000013316,ENSDARG00000045186,ENSDARG00000071632,ENSDARG00000045185,ENSDARG00000071633" WBGene00000776(cpl-1) ENSXETG00000027581(ctsl2) "ENSMUSG00000021477(Ctsl),ENSMUSG00000042243(BC051665),ENSMUSG00000056728(Ctsll3),ENSMUSG00000050345(4930486L24Rik),ENSMUSG00000074871(Ctsm),ENSMUSG00000057446(Cts8)" "ENSG00000135047(CTSL1),ENSG00000136943(CTSL2)" "viable,increased cell death,fertile,visible,recessive,female sterile,non-suppressor of variegation,dominant,male fertile,body color defective" "female germline cell,egg,wing,adult abdominal segment 1,adult abdominal segment 2,adult abdominal segment 3,adult abdominal segment 4,adult abdominal segment 5" FBgn0032292 EMC3 ER Membrane protein Complex 3 http://flybase.net/reports/FBgn0032292.html protein_coding_gene "0016063=rhodopsin biosynthetic process, 0042052=rhabdomere development, 0042060=wound healing" "0005783=endoplasmic reticulum, 0016020=membrane, 0012505=endomembrane system" "dPob, CG6750" "IPR008568=Uncharacterised conserved protein UCP010045, transmembrane eukaryotic, IPR002809=Protein of unknown function DUF106, transmembrane" CG6750 16-Dec-15 2015_12 "ENSDARG00000029479(zgc:86609),ENSDARG00000020607(pob)" YKL207W(AIM27) WBGene00013378(Y62E10A.10) ENSXETG00000005484(TMEM111) ENSMUSG00000030286(Tmem111) ENSG00000125037(TMEM111) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053329 Sp212 Serine-peptidase 212 http://flybase.net/reports/FBgn0053329.html protein_coding_gene 0004252=serine-type endopeptidase activity "0009617=response to bacterium, 0009620=response to fungus, 0006508=proteolysis" "CG33329, unnamed, ORE-5, SP212" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG33329 16-Dec-15 2015_12 "ENSDARG00000068726(LOC100002060),ENSDARG00000007988(masp2)" "ENSMUSG00000027249(F2),ENSMUSG00000031444(F10),ENSMUSG00000059481(Plg),ENSMUSG00000024386(Proc),ENSMUSG00000031138(F9),ENSMUSG00000031443(F7)" DRSC22930 K -1.067276024 0.37768832 -0.581534434 0.364136404 1.584074022 0.406044151 FBgn0038461 CG3678 http://flybase.net/reports/FBgn0038461.html protein_coding_gene 0005875=microtubule associated complex RE62710p "IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain" CG3678 16-Dec-15 2015_12 ENSDARG00000003308 YJR088C(EMC2) WBGene00021973(Y57G7A.10) ENSXETG00000003604(TEgg055h07.1) ENSMUSG00000022337(Ttc35) ENSG00000104412(TTC35) FBgn0034577 cpa capping protein alpha http://flybase.net/reports/FBgn0034577.html protein_coding_gene 0046982=protein heterodimerization activity "0030036=actin cytoskeleton organization, 0051489=regulation of filopodium assembly, 0006909=phagocytosis, 0046329=negative regulation of JNK cascade, 0030837=negative regulation of actin filament polymerization, 0010591=regulation of lamellipodium assembly, 0007294=germarium-derived oocyte fate determination, 0000902=cell morphogenesis, 0051490=negative regulation of filopodium assembly, 0051016=barbed-end actin filament capping, 0007015=actin filament organization, 0007018=microtubule-based movement, 0035220=wing disc development" "0005912=adherens junction, 0016324=apical plasma membrane, 0005869=dynactin complex, 0005875=microtubule associated complex, 0008290=F-actin capping protein complex" "scrd, capping protein alpha, Capping Protein, capping proteinalpha, Capping alpha, CG10540, miro, Capping protein alpha, Cpa" "IPR017865=F-actin capping protein, alpha subunit, conserved site, IPR002189=F-actin-capping protein subunit alpha" CG10540 16-Dec-15 2015_12 "ENSDARG00000056090(capza1b),ENSDARG00000034240(LOC100333712)" YKL007W(CAP1) WBGene00000292(cap-1) "ENSXETG00000025061(capza2),ENSXETG00000021760(capza1)" "ENSMUSG00000070372(Capza1),ENSMUSG00000015733(Capza2),ENSMUSG00000055357" "ENSG00000116489(CAPZA1),ENSG00000198898(CAPZA2)" "increased cell death,heat sensitive,decreased cell death,increased cell growth,lethal,recessive,visible,somatic clone,cell lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage" "wing disc,wing hinge primordium,posterior compartment,heat sensitive,eye,somatic clone,actin cytoskeleton & eye disc | somatic clone,wing,macrochaeta,egg chamber,germline clone,oocyte,oocyte nucleus,follicle cell,filopodium | supernumerary,actin cytoskeletonHml.PG" FBgn0267348 LanB2 Laminin B2 http://flybase.net/reports/FBgn0267348.html "FBgn0002528, FBgn0025207, FBgn0261435, FBgn0002204" protein_coding_gene "0007435=salivary gland morphogenesis, 0085029=extracellular matrix assembly, 0048598=embryonic morphogenesis, 0070831=basement membrane assembly, 0034446=substrate adhesion-dependent cell spreading, 0033627=cell adhesion mediated by integrin, 0061031=endodermal digestive tract morphogenesis, 0007494=midgut development, 0009888=tissue development, 0009887=organ morphogenesis" "0012505=endomembrane system, 0005605=basal lamina, 0031012=extracellular matrix, 0005604=basement membrane" "laminin gamma, DROLAMB2A, anon-EST:fe2H3, knod, laminin gamma2, laminin, laminin gamma-chain, LM-B2/gamma, LamininB2, LAMB2A, lanB2, lamininB, CT11145, l(3)67BDb, lethal (3) 67BDb, CG3322, laminin B2, Lam-B2, LMG1, laminin B2 subunit, laminin gamma1, knodel, anon-fast-evolving-2H3, gamma1, lamB2, Laminin" "IPR000034=Laminin IV, IPR008211=Laminin, N-terminal, IPR031082=Laminin subunit gamma, IPR008979=Galactose-binding domain-like, IPR002049=Laminin EGF domain" CG3322 16-Dec-15 2015_12 ENSDARG00000036279(lamc1) WBGene00016913(lam-2) ENSXETG00000012525(LAMC1) ENSMUSG00000026478(Lamc1) ENSG00000135862(LAMC1) " embryonic stage | stage 11-12 , embryonic stage , embryonic stage | late , embryonic stage | stage >12 " " head mesoderm

, somatic mesoderm

, ventral nerve cord

, ectoderm

, interface glial cell

, embryonic/larval midgut

, glial cell | lateral

, hemocyte

, ventral midline

, embryonic/larval fat body

, sense organ

, embryonic brain

, visceral mesoderm

" " embryonic stage | stage 13-15 , embryonic stage | 10-13 hr " " segmental nerve

, intersegmental nerve

, embryonic/larval digestive system

, myoblast &&of larval muscle system

, epidermis

, neuropil associated CNS glial cell

" FBgn0030803 CG4880 http://flybase.net/reports/FBgn0030803.html protein_coding_gene IPR027417=P-loop containing nucleoside triphosphate hydrolase CG4880 16-Dec-15 2015_12 ENSMUSG00000059555(A830007P12Rik) viable FBgn0025716 Bap55 Brahma associated protein 55kD http://flybase.net/reports/FBgn0025716.html FBgn0034216 protein_coding_gene 0003713=transcription coactivator activity "0016573=histone acetylation, 0007067=mitotic nuclear division, 0048813=dendrite morphogenesis, 0043486=histone exchange, 0006281=DNA repair, 0006357=regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0045893=positive regulation of transcription, DNA-templated, 0070983=dendrite guidance, 0000281=mitotic cytokinesis, 2000637=positive regulation of gene silencing by miRNA, 0006338=chromatin remodeling" "0031011=Ino80 complex, 0035267=NuA4 histone acetyltransferase complex, 0035060=brahma complex, 0070604=PBAF complex" "bap55, BAF53, BAP47, Brahma associated protein 55 kD, BRM-associated protein 55, Baf53, CG6546, brahma associated protein of 55kD, BAP55" "IPR004000=Actin family, IPR027667=Actin-related protein 4" CG6546 16-Dec-15 2015_12 "ENSDARG00000070828(actl6a),ENSDARG00000034107(zgc:110167)" WBGene00022774(ZK616.4) ENSXETG00000007260(BC064183.1) "ENSMUSG00000029712(Actl6b),ENSMUSG00000027671(Actl6a)" "ENSG00000077080(ACTL6B),ENSG00000136518(ACTL6A)" "lethal,partially lethal - majority die,visible,neuroanatomy defective,recessive,decreased cell number" "embryonic/larval brain,mesothoracic tergum,adult antennal lobe projection neuron DL1 adPN" DRSC07000 IE -0.232029448 -1.869431272 -0.390115784 -3.401777305 -0.213797607 -1.31363322 FBgn0086656 shrb shrub http://flybase.net/reports/FBgn0086656.html "FBgn0033385, FBgn0028565, FBgn0062188" protein_coding_gene 0005515=protein binding "0000281=mitotic cytokinesis, 0045746=negative regulation of Notch signaling pathway, 0008593=regulation of Notch signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0032509=endosome transport via multivesicular body sorting pathway, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0016322=neuron remodeling, 0044130=negative regulation of growth of symbiont in host, 0048812=neuron projection morphogenesis, 0007034=vacuolar transport, 0048132=female germ-line stem cell asymmetric division, 0006914=autophagy, 0048813=dendrite morphogenesis" "0005771=multivesicular body, 0070938=contractile ring, 0045169=fusome, 0030496=midbody, 0000815=ESCRT III complex" "CG8055, Shrb, anon-WO0118547.180, vps32, Shrub, Vps32, shrub, vps32/snf7, ESCRT-III, Snf7, Snf7/Vps32, Dvps32, DmSNF2" IPR005024=Snf7 family CG8055 16-Dec-15 2015_12 "ENSDARG00000007323(chmp4b),ENSDARG00000016255(zgc:56112),ENSDARG00000007418(chmp4c)" YLR025W(SNF7) "WBGene00016961(vps-32.1),WBGene00016497(vps-32.2)" "ENSXETG00000010425(CHMP4C),ENSXETG00000021424(CHMP4B)" "ENSMUSG00000038467(Chmp4b),ENSMUSG00000027536(Chmp4c)" "ENSG00000101421(CHMP4B),ENSG00000164695(CHMP4C),ENSG00000100931" DRSC07061 I -0.58697176 -1.58324944 0.887668018 -1.351358156 -0.861500412 -1.497838754 FBgn0044030 mRpS14 mitochondrial ribosomal protein S14 http://flybase.net/reports/FBgn0044030.html "FBgn0031019, FBgn0052531" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005761=mitochondrial ribosome, 0005763=mitochondrial small ribosomal subunit" "Mitochondrial ribosomal protein S14, MRP-S14, cg12211, MrpS14, S14, CG12211, CG32531" IPR001209=Ribosomal protein S14 CG32531 16-Dec-15 2015_12 ENSDARG00000068305(zgc:153664) YPR166C(MRP2) WBGene00011334(T01E8.6) ENSXETG00000020045(mrps14) ENSMUSG00000058267(Mrps14) ENSG00000120333(MRPS14) "viable,visible" trichogen cell FBgn0052669 CG32669 http://flybase.net/reports/FBgn0052669.html protein_coding_gene "0005215=transporter activity, 0008523=sodium-dependent multivitamin transmembrane transporter activity" "0006810=transport, 0051180=vitamin transport, 0055085=transmembrane transport" "0016020=membrane, 0016021=integral component of membrane" dSLC5A4 "IPR019900=Sodium/solute symporter, subgroup, IPR001734=Sodium/solute symporter" CG32669 16-Dec-15 2015_12 "ENSDARG00000042859(si:dkey-5g7.3),ENSDARG00000014599(zgc:114067),ENSDARG00000003697(slc5a8l),ENSDARG00000005004" YHL016C(DUR3) WBGene00014092(ZK822.5) "ENSXETG00000025601(SLC5A12),ENSXETG00000013546(SLC5A5),ENSXETG00000002542(slc5a8)" "ENSMUSG00000020062(Slc5a8),ENSMUSG00000041644(Slc5a12),ENSMUSG00000000792(Slc5a5),ENSMUSG00000006641(Slc5a6)" "ENSG00000139357,ENSG00000148942(SLC5A12),ENSG00000105641(SLC5A5),ENSG00000138074(SLC5A6)" viable FBgn0025725 ë±COP Coat Protein (coatomer) ë± http://flybase.net/reports/FBgn0025725.html protein_coding_gene 0005198=structural molecule activity "0007112=male meiosis cytokinesis, 0006909=phagocytosis, 0048812=neuron projection morphogenesis, 0010883=regulation of lipid storage, 0006890=retrograde vesicle-mediated transport, Golgi to ER, 0000902=cell morphogenesis, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport" 0030126=COPI vesicle coat "alphaCOP, alpha-COP, CG7961, alphaCop, coatomer I, COPI alpha subunit, alpha-coatomer protein" "IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR016391=Coatomer alpha subunit, IPR006692=Coatomer, WD associated region, IPR010714=Coatomer, alpha subunit, C-terminal, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat" CG7961 16-Dec-15 2015_12 ENSDARG00000004173(copa) YDL145C(COP1) WBGene00022119(Y71F9AL.17) ENSXETG00000005840(COPA) ENSMUSG00000026553(Copa) ENSG00000122218(COPA) "lethal,viable,fertile" "onion stage spermatid,astral microtubule | malebam.THsimVP16,spindle microtubule | malebam.THsimVP16" DRSC08706 IE -0.51004758 1.82271904 1.387286071 -3.141692274 0.035042846 -1.329560631 FBgn0038855 CG5745 http://flybase.net/reports/FBgn0038855.html protein_coding_gene 0005096=GTPase activator activity "0006909=phagocytosis, 0043087=regulation of GTPase activity" IPR000195=Rab-GTPase-TBC domain CG5745 16-Dec-15 2015_12 "ENSDARG00000045510(tbc1d22a),ENSDARG00000026988(LOC557377)" YOR070C(GYP1) WBGene00009322(tbc-3) ENSXETG00000023322(tbc1d22a) "ENSMUSG00000042203(Tbc1d22b),ENSMUSG00000051864(Tbc1d22a)" "ENSG00000065491(TBC1D22B),ENSG00000054611(TBC1D22A)" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0033907 mRpS16 mitochondrial ribosomal protein S16 http://flybase.net/reports/FBgn0033907.html FBgn0062878 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "MRP-S16, CG8338, 147189_at, BcDNA:SD15809" "IPR000307=Ribosomal protein S16, IPR023803=Ribosomal protein S16 domain" CG8338 16-Dec-15 2015_12 ENSDARG00000005833 YPL013C(MRPS16) WBGene00018961(F56D1.3) ENSXETG00000001399(mrps16) ENSMUSG00000049960(Mrps16) ENSG00000182180(MRPS16) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033375 CG8078 http://flybase.net/reports/FBgn0033375.html FBgn0061679 protein_coding_gene 0000049=tRNA binding "0034227=tRNA thio-modification, 0002098=tRNA wobble uridine modification" 0005829=cytosol anon-WO0118547.76 "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR000541=Cytoplasmic tRNA 2-thiolation protein 1, IPR020554=Uncharacterised protein family UPF0021, conserved site, IPR012089=2-thiocytidine tRNA biosynthesis protein, TtcA, IPR011063=tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal" CG8078 16-Dec-15 2015_12 ENSDARG00000020986(zgc:55395) YGL211W(NCS6) WBGene00017928(tut-1) ENSXETG00000004036(Q5FW05_XENTR) ENSMUSG00000038888(Ctu1) "ENSG00000142544(CTU1),ENSG00000213818" "viable,visible" "tormogen cell,mesothoracic tergum" FBgn0037374 jagn jagunal http://flybase.net/reports/FBgn0037374.html protein_coding_gene "0051686=establishment of ER localization, 0022416=chaeta development, 0007296=vitellogenesis, 0006887=exocytosis, 0007029=endoplasmic reticulum organization, 0001555=oocyte growth, 0007018=microtubule-based movement, 0008407=chaeta morphogenesis, 0048477=oogenesis, 0007303=cytoplasmic transport, nurse cell to oocyte" 0005789=endoplasmic reticulum membrane CG10978 IPR009787=Protein jagunal CG10978 16-Dec-15 2015_12 "ENSDARG00000041071(jagn1a),ENSDARG00000014995(jagn1b)" WBGene00010579(K05C4.2) ENSXETG00000009133(jagn1) ENSMUSG00000051256(Jagn1) ENSG00000171135(JAGN1) "lethal,recessive,partially lethal - majority die" "oocyte,germline clone,nurse cell,macrochaeta,somatic clone,microchaeta,wing margin bristle,endoplasmic reticulum & oocyte | germ-line clone,yolk granule & oocyte | germ-line clone,microvillus & oocyte | germ-line clone" FBgn0262716 Arp3 Actin-related protein 3 http://flybase.net/reports/FBgn0262716.html "FBgn0086714, FBgn0011744, FBgn0046458" protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005524=ATP binding, 0003779=actin binding" "0008064=regulation of actin polymerization or depolymerization, 0030036=actin cytoskeleton organization, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0007520=myoblast fusion, 0072553=terminal button organization, 0051491=positive regulation of filopodium assembly, 0097320=membrane tubulation, 0030589=pseudocleavage involved in syncytial blastoderm formation, 0006909=phagocytosis, 0030713=ovarian follicle cell stalk formation, 0007413=axonal fasciculation, 0010592=positive regulation of lamellipodium assembly, 0007010=cytoskeleton organization, 0000902=cell morphogenesis, 0022416=chaeta development, 0045747=positive regulation of Notch signaling pathway, 0034314=Arp2/3 complex-mediated actin nucleation, 0030037=actin filament reorganization involved in cell cycle, 0006886=intracellular protein transport" "0005885=Arp2/3 protein complex, 0005884=actin filament, 0015629=actin cytoskeleton, 0030027=lamellipodium" "Actr66B, Actin-related protein, Actin-related protein 66B, arp66B, ARP3, Arp3, actin-related protein-3, Arp66B, AcTr66B, arp66b, arp3, anon-WO0172774.138, CG7558, schwachling" "IPR020902=Actin/actin-like conserved site, IPR004000=Actin family, IPR015623=Actin-related protein 3" CG7558 16-Dec-15 2015_12 ENSDARG00000008790(zgc:158823) YJR065C(ARP3) WBGene00000199(arx-1) ENSXETG00000015291(BC064225.1) ENSMUSG00000026341(Actr3) "ENSG00000115091(ACTR3),ENSG00000133627(ACTR3B)" oogenesis stage | stage S9 nurse cell ring canal

FBgn0039087 CG10168 http://flybase.net/reports/FBgn0039087.html protein_coding_gene 0003851=2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG10168 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable DRSC14198 I -2.540109312 0.618495356 0.034856365 -0.435100373 0.994190363 -1.174256007 FBgn0027087 Aats-his Histidyl-tRNA synthetase http://flybase.net/reports/FBgn0027087.html "FBgn0027288, FBgn0028314, FBgn0030934" protein_coding_gene "0005524=ATP binding, 0004821=histidine-tRNA ligase activity" 0006427=histidyl-tRNA aminoacylation 0005829=cytosol "l(1)G0358, CG6335, l(1)G0165, HRS, Harsl, HisRS" "IPR006195=Aminoacyl-tRNA synthetase, class II, IPR015807=Histidine-tRNA ligase, IPR009068=S15/NS1, RNA-binding, IPR004154=Anticodon-binding, IPR004516=Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit, IPR000738=WHEP-TRS domain" CG6335 16-Dec-15 2015_12 ENSDARG00000003693(hars) YPR033C(HTS1) WBGene00002001(hars-1) ENSXETG00000002665() "ENSMUSG00000001380(Hars),ENSMUSG00000019143(Hars2)" "ENSG00000170445(HARS),ENSG00000112855(HARS2)" embryonic stage embryonic/larval muscle system

"lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,some die during pupal stage" FBgn0029943 Atg5 Autophagy-related 5 http://flybase.net/reports/FBgn0029943.html protein_coding_gene 0019776=Atg8 ligase activity "0006914=autophagy, 0016236=macroautophagy, 0035071=salivary gland cell autophagic cell death, 0035096=larval midgut cell programmed cell death, 1902350=cellular response to chloroquine, 0048102=autophagic cell death" "0005776=autophagic vacuole, 0005737=cytoplasm, 0034274=Atg12-Atg5-Atg16 complex" "ATG5, autophagy-specific gene 5, DmAtg5, unnamed, Autophagy-specific gene 5, atg5, CG1643" IPR007239=Autophagy-related protein 5 CG1643 16-Dec-15 2015_12 ENSDARG00000023396(atg5) YPL149W(ATG5) WBGene00022152(atg-5) ENSXETG00000008672(ATG5) ENSMUSG00000038160(Atg5) ENSG00000057663(ATG5) pupal stage salivary gland

"viable,fertile,chemical sensitive,immune response defective,RU486 conditional" fat body FBgn0039595 AstA-R2 Allatostatin A receptor 2 http://flybase.net/reports/FBgn0039595.html "FBgn0044357, FBgn0046611, FBgn0046612" protein_coding_gene "0008188=neuropeptide receptor activity, 0004983=neuropeptide Y receptor activity, 0008261=allatostatin receptor activity, 0004930=G-protein coupled receptor activity" "0007186=G-protein coupled receptor signaling pathway, 0007218=neuropeptide signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane" "DAR, Allatostatin Receptor 2, DAR2, ASA-receptor, anon-WO0131005.7, ASTR, anon-WO0170980.115, D.AlstR2, AR-2, DAR-2, anon-WO0170980.116, Allatostatin A receptor 2, CG10001" "IPR000611=Neuropeptide Y receptor family, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG10001 16-Dec-15 2015_12 "ENSDARG00000067563(kiss1rb),ENSDARG00000002728(kiss1ra)" WBGene00013974(npr-9) "ENSXETG00000012621(GALR2),ENSXETG00000009147(),ENSXETG00000006335(),ENSXETG00000014693(GALR1)" "ENSMUSG00000020793(Galr2),ENSMUSG00000047429(Galr3),ENSMUSG00000024553(Galr1)" "ENSG00000166573(GALR1),ENSG00000182687(GALR2)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0033457 Ntmt N-terminal methyltransferase http://flybase.net/reports/FBgn0033457.html protein_coding_gene "0071885=N-terminal protein N-methyltransferase activity, 0042054=histone methyltransferase activity" "0035568=N-terminal peptidyl-proline methylation, 0018016=N-terminal peptidyl-proline dimethylation, 0016571=histone methylation" 0005634=nucleus "dNTMT, CG1675" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR008576=Alpha-N-methyltransferase NTM1" CG1675 16-Dec-15 2015_12 "ENSDARG00000022399,ENSDARG00000042033(si:ch211-214d2.2)" YBR261C(TAE1) WBGene00022277(Y74C9A.3) "ENSXETG00000014162(METTL11A),ENSXETG00000004731(METTL11B)" "ENSMUSG00000026857(Mettl11a),ENSMUSG00000040113(Mettl11b)" "ENSG00000148335(METTL11A),ENSG00000203740(METTL11B)" viable FBgn0010315 CycD Cyclin D http://flybase.net/reports/FBgn0010315.html protein_coding_gene "0016538=cyclin-dependent protein serine/threonine kinase regulator activity, 0005515=protein binding" "0008283=cell proliferation, 0030307=positive regulation of cell growth, 0016049=cell growth, 0007005=mitochondrion organization, 0007259=JAK-STAT cascade" 0005634=nucleus "CDI3, CG9096, DmcycD, cdi3, CYCD, cyclin D, Cyclin-dependent kinase interactor 3, CyclinD, cyclinD, dCycD, dCyclinD, cycD, Cyc D, Cdi3" "IPR006671=Cyclin, N-terminal, IPR013763=Cyclin-like, IPR004367=Cyclin, C-terminal domain" CG9096 16-Dec-15 2015_12 "ENSDARG00000051748(ccnd2a),ENSDARG00000070408(ccnd2b),ENSDARG00000035750(ccnd1)" WBGene00000870(cyd-1) "ENSXETG00000005972(CCND2),ENSXETG00000000267(TEgg076j23.1),ENSXETG00000003800(CCND1)" "ENSMUSG00000070348(Ccnd1),ENSMUSG00000000184(Ccnd2),ENSMUSG00000034165(Ccnd3)" "ENSG00000118971(CCND2),ENSG00000110092(CCND1),ENSG00000112576(CCND3)" " larval stage | third instar , embryonic stage | early , embryonic stage&&larval stage , adult stage | male , adult stage | female " " imaginal disc

, morphogenetic furrow | anterior

, eye-antennal disc

" "viable,sterile,recessive,small body,decreased cell number,increased cell size,somatic clone,size defective,wild-type,large body,increased cell number,decreased cell size" "wing,somatic clone,embryonic/larval midgut primordium" DRSC20233 IE -2.774952185 -3.585361354 -4.689582149 -2.175471354 -1.126952096 -0.50847421 FBgn0004237 Hrb87F Heterogeneous nuclear ribonucleoprotein at 87F http://flybase.net/reports/FBgn0004237.html FBgn0010230 protein_coding_gene "0043565=sequence-specific DNA binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0009408=response to heat, 0001745=compound eye morphogenesis, 0042594=response to starvation, 0008585=female gonad development, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007067=mitotic nuclear division, 0022008=neurogenesis" "0030529=ribonucleoprotein complex, 0005634=nucleus, 0005654=nucleoplasm, 0005703=polytene chromosome puff, 0000785=chromatin, 0035062=omega speckle" "Hrp36, hnRNP A2/B1, hnRNPA1/A2, hrp40, Hrb2, Q14, P11, Heterogeneous nuclear ribonucleoprotein at 85CD, hnRNA-binding protein 2, hnRNP36, HRB87F/hrp36, p38, HRB87F, Q16, hnRNPA2, Hrb85CD, CG12749, P11/Hrb87F, Hrb87Fa, hnRNPA1, Hrb87f, HRP36, hrp36" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG12749 16-Dec-15 2015_12 "ENSDARG00000036675(hnrnpa1),ENSDARG00000059351(hnrnpa3)" WBGene00001999(hrp-1) "ENSXETG00000001806(HNRNPA3),ENSXETG00000021277(hnrpa1),ENSXETG00000012170(hnrpa2b1)" "ENSMUSG00000046434(Hnrnpa1),ENSMUSG00000059005(Hnrnpa3),ENSMUSG00000004980(Hnrnpa2b1),ENSMUSG00000060989,ENSMUSG00000059179" "ENSG00000135486(HNRNPA1),ENSG00000139675(HNRNPA1L2),ENSG00000170144(HNRNPA3),ENSG00000122566(HNRNPA2B1),ENSG00000215492" " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

"viable,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16708 K -0.722385229 -0.234529108 0.041035676 -0.460785574 -2.914010715 -0.463847677 FBgn0003942 RpS27A Ribosomal protein S27A http://flybase.net/reports/FBgn0003942.html "FBgn0002728, FBgn0010585, FBgn0064114" protein_coding_gene "0031386=protein tag, 0003735=structural constituent of ribosome" "0016567=protein ubiquitination, 0006412=translation" "0022627=cytosolic small ribosomal subunit, 0005875=microtubule associated complex, 0005840=ribosome" "Ubi-f80, Ubiq, Ubiquitin-monomeric, male female sterile 31, mfs48, UB3-D, mfs(2)48, DUb80, Ubiquitin fusion 80, mfs(2)31, l(2)04820, ubiquitin, Dub80, Ubi-m, l(2)31Ei, CG5271, Ubiquitin" "IPR002906=Ribosomal protein S27a, IPR000626=Ubiquitin domain, IPR019954=Ubiquitin conserved site, IPR011332=Zinc-binding ribosomal protein, IPR029071=Ubiquitin-related domain, IPR019956=Ubiquitin" CG5271 16-Dec-15 2015_12 ENSDARG00000032725(rps27a) YLR167W(RPS31) WBGene00006725(ubl-1) ENSXETG00000004519(RPS27A) "ENSMUSG00000020460(Rps27a),ENSMUSG00000058838(Rps27a-ps2)" ENSG00000143947(RPS27A) " larval stage | third instar , embryonic stage -- adult stage , adult stage " " embryonic/larval salivary gland

, embryonic/larval fat body

, ovary

, imaginal disc

, Malpighian tubule

" "lethal,recessive,female sterile,heat sensitive,male sterile,viable,reduced" "macrochaeta,spermatid" DRSC03421 IEK -2.04996412 -1.37594847 -2.306200434 -4.359150613 1.114867295 2.87032859 FBgn0027106 Inx7 Innexin 7 http://flybase.net/reports/FBgn0027106.html protein_coding_gene 0005243=gap junction channel activity "0010496=intercellular transport, 0007476=imaginal disc-derived wing morphogenesis, 0072375=medium-term memory" "0005737=cytoplasm, 0005634=nucleus, 0005921=gap junction, 0016021=integral component of membrane" "innexin 7, D-inx-7, FBpp0070994, inx7, Innexin7, CG2977, pas related protein 7, CG32731, inx-7, Dm-inx7, innexin7, prp7" IPR000990=Innexin CG2977 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" "neuroanatomy defective,memory defective,heat sensitive,viable,fertile" "presumptive embryonic/larval central nervous system,ventral nerve cord | embryonic stage,presumptive embryonic/larval peripheral nervous system,anterior commissure | embryonic stage,posterior commissure | embryonic stage,longitudinal connective | embryonic stage" FBgn0014857 His3.3A Histone H3.3A http://flybase.net/reports/FBgn0014857.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0007155=cell adhesion, 0007140=male meiosis, 0008360=regulation of cell shape, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005700=polytene chromosome" "H3L-like histone, histone H3.3A, histone variant H3.3, histone H3.3, H3.3A, H3.3, dH3.3A, CG5825, His3.3, His-3.3A, histone H3.3 variant, PH3, histone variant 3.3" "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG5825 16-Dec-15 2015_12 "ENSDARG00000033009(h3f3c),ENSDARG00000020504(h3f3a),ENSDARG00000068436(LOC100331798),ENSDARG00000045248(zgc:56418),ENSDARG00000068434(zgc:110292)" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001945(his-71) "ENSXETG00000012575(TGas113e22.1),ENSXETG00000022641(TGas113e22.1),ENSXETG00000027927(TGas113e22.1)" "ENSMUSG00000016559(H3f3b),ENSMUSG00000060743(H3f3a)" "ENSG00000196285,ENSG00000163041(H3F3A),ENSG00000132475(H3F3B)" spermatogenesis && adult stage testis

" spermatogenesis && adult stage , larval stage " " protein body

, spermatocyte

, Y chromosome loop

, larval salivary gland

, spermatid

" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC03343 IEK -1.300171076 -4.616387217 -1.703889291 -2.626317686 0.327610113 1.778029732 FBgn0032664 CG5755 http://flybase.net/reports/FBgn0032664.html FBgn0044715 protein_coding_gene anon-WO0140519.163 "IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG5755 16-Dec-15 2015_12 ENSDARG00000035181(slc25a46) WBGene00012740(Y40B1B.8) ENSXETG00000021256(TEgg014d12.1) ENSMUSG00000024259(Slc25a46) ENSG00000164209(SLC25A46) "partially lethal - majority die,some die during pupal stage" FBgn0024963 GluClë± GluClë± http://flybase.net/reports/FBgn0024963.html FBgn0063176 protein_coding_gene 0008068=extracellular-glutamate-gated chloride channel activity "0048812=neuron projection morphogenesis, 0006811=ion transport" "0016021=integral component of membrane, 0005886=plasma membrane" "CG7535, DmGlu, GluCl, BcDNA:HL07853, glu, DmGluClalpha, Dm-GluCl, DrosGlu-Cl-alpha, dGluCl-alpha, indefinite, glutamate-gated chloride channel, glc, GLUCL, CT23049, DrosGluCl-alpha, GluClalpha, GluCla, DrosGluCl, DrosGluCl-alpha1" "IPR015680=Glutamate-Gated Chloride Channel, IPR006201=Neurotransmitter-gated ion-channel, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain" CG7535 16-Dec-15 2015_12 "ENSDARG00000012019(glra1),ENSDARG00000011066" "WBGene00000232(avr-14),WBGene00001593(glc-3),WBGene00000233(avr-15),WBGene00001591(glc-1)" "ENSXETG00000002460(GLRA3),ENSXETG00000011875(GLRA2),ENSXETG00000001966(GLRA1),ENSXETG00000019533(GLRB)" "ENSMUSG00000038257(Glra3),ENSMUSG00000018595(Glra4),ENSMUSG00000018589(Glra2),ENSMUSG00000000263(Glra1),ENSMUSG00000028020(Glrb)" "ENSG00000145451(GLRA3),ENSG00000145888(GLRA1),ENSG00000101958(GLRA2),ENSG00000188828(GLRA4),ENSG00000109738(GLRB)" " embryonic stage , adult stage , larval stage " viable FBgn0013675 mt:CoII mitochondrial Cytochrome c oxidase subunit II http://flybase.net/reports/FBgn0013675.html FBgn0002867 protein_coding_gene "0004129=cytochrome-c oxidase activity, 0005507=copper ion binding" "0006123=mitochondrial electron transport, cytochrome c to oxygen, 0022900=electron transport chain" "0005739=mitochondrion, 0016021=integral component of membrane, 0005743=mitochondrial inner membrane, 0005751=mitochondrial respiratory chain complex IV" "CO, Cox2, cytochrome c oxidase, cytochrome c, mt COII, Cytochrome c oxidase subunit II, CcO subunit II, CO II, MT-CO2, mt-CO2, cytochrome c oxidase subunit II, COX, cox2, CG34069, CO2, COII, cytochrome oxidase II, COXII, II, CoII" "IPR014222=Cytochrome c oxidase, subunit II, IPR008972=Cupredoxin, IPR001505=Copper centre Cu(A), IPR011759=Cytochrome C oxidase subunit II, transmembrane domain, IPR002429=Cytochrome c oxidase subunit II C-terminal" CG34069 16-Dec-15 2015_12 ENSDARG00000063908 Q0250(COX2) WBGene00010965(MTCE.31) ENSMUSG00000064354 ENSG00000198712 FBgn0011837 Tis11 Tis11 homolog http://flybase.net/reports/FBgn0011837.html "FBgn0063277, FBgn0027302" protein_coding_gene "0046872=metal ion binding, 0035925=mRNA 3'-UTR AU-rich region binding, 0003677=DNA binding, 0003730=mRNA 3'-UTR binding" "0016246=RNA interference, 0010629=negative regulation of gene expression, 1900153=positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, 0061158=3'-UTR-mediated mRNA destabilization" "0005829=cytosol, 0005634=nucleus" "TIS11cc1, CG4070, dTis11, l(1)G0124, DTIS11, TIScc1, clone 1.28, dTTP, tis-11, anon-EST:Liang-1.28, Ts11, TIS11" "IPR000571=Zinc finger, CCCH-type" CG4070 16-Dec-15 2015_12 "ENSDARG00000021806(zgc:76924),ENSDARG00000016154(zfp36l2),ENSDARG00000021443(zfp36l1b),ENSDARG00000040503" "WBGene00003388(moe-3),WBGene00003865(oma-2),WBGene00003864(oma-1)" "ENSXETG00000016987(ZFP36L1),ENSXETG00000009274(ZFP36L2)" "ENSMUSG00000045817(Zfp36l2),ENSMUSG00000021127(Zfp36l1)" " embryonic stage | early , embryonic stage | >3hr " "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible" "eye,retinal pigment cell,rhabdomerelz-gal4" FBgn0030096 Zpr1 Zpr1 http://flybase.net/reports/FBgn0030096.html protein_coding_gene 0008270=zinc ion binding "0035149=lumen formation, open tracheal system, 0007430=terminal branching, open tracheal system, 0006360=transcription from RNA polymerase I promoter" 0005730=nucleolus "CG9060, Zinc finger Protein 1" "IPR004457=Zinc finger, ZPR1-type" CG9060 16-Dec-15 2015_12 ENSDARG00000043542(znf259) YGR211W(ZPR1) WBGene00020999(W03F9.1) ENSXETG00000003765(ZNF259) ENSMUSG00000032078(Zfp259) ENSG00000109917(ZNF259) "viable,visible" "embryonic/larval trachea,somatic clone,tracheal lumen,trichogen cell" FBgn0010747 Srp54k Signal recognition particle protein 54k http://flybase.net/reports/FBgn0010747.html FBgn0027916 protein_coding_gene "0005525=GTP binding, 0008312=7S RNA binding, 0005048=signal sequence binding, 0003924=GTPase activity" "0006617=SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition, 0006614=SRP-dependent cotranslational protein targeting to membrane" "0005786=signal recognition particle, endoplasmic reticulum targeting" "CG4659, l(3)01418, BcDNA:GM09489, Srp54, BcDNA.GM09489" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR006325=Signal recognition particle, SRP54 subunit, eukaryotic, IPR013822=Signal recognition particle, SRP54 subunit, helical bundle, IPR022941=Signal recognition particle, SRP54 subunit, IPR004125=Signal recognition particle, SRP54 subunit, M-domain, IPR003593=AAA+ ATPase domain, IPR000897=Signal recognition particle, SRP54 subunit, GTPase domain" CG4659 16-Dec-15 2015_12 ENSDARG00000003813(srp54) YPR088C(SRP54) WBGene00009012(F21D5.7) ENSXETG00000012290(SRP54) "ENSMUSG00000079108(Srp54b),ENSMUSG00000021020(Srp54a)" ENSG00000100883(SRP54) "lethal,recessive" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0030669 CG9240 http://flybase.net/reports/FBgn0030669.html FBgn0027703 protein_coding_gene 0008236=serine-type peptidase activity 0006627=protein processing involved in protein targeting to mitochondrion "0005740=mitochondrial envelope, 0016021=integral component of membrane" anon-EST:Posey267 "IPR019759=Peptidase S24/S26A/S26B, IPR019533=Peptidase S26, IPR000223=Peptidase S26A, signal peptidase I, IPR015927=Peptidase S24/S26A/S26B/S26C, IPR019758=Peptidase S26A, signal peptidase I, conserved site, IPR028360=Peptidase S24/S26, beta-ribbon domain, IPR026730=Mitochondrial inner membrane protease subunit 1" CG9240 16-Dec-15 2015_12 ENSDARG00000045935(immp1l) YMR150C(IMP1) WBGene00007021(immp-1) ENSXETG00000008178(TEgg068a14.1) "ENSMUSG00000042670(Immp1l),ENSMUSG00000051116(Gm8121)" ENSG00000148950(IMMP1L) viable FBgn0035767 CG8596 http://flybase.net/reports/FBgn0035767.html protein_coding_gene 0055085=transmembrane transport 0016021=integral component of membrane cln7 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8596 16-Dec-15 2015_12 ENSDARG00000015179(mfsd8) "WBGene00021814(Y53G8AR.7),WBGene00012280(W05E10.1),WBGene00017861(F27D9.2),WBGene00013996(ZK550.2),WBGene00020889(T28C12.2),WBGene00020888(T28C12.1),WBGene00012170(W01B6.3)" ENSXETG00000022531(MFSD8) ENSMUSG00000025759(Mfsd8) ENSG00000164073(MFSD8) viable FBgn0035785 ppk26 pickpocket 26 http://flybase.net/reports/FBgn0035785.html protein_coding_gene "0005272=sodium channel activity, 0015280=ligand-gated sodium channel activity" "0050966=detection of mechanical stimulus involved in sensory perception of pain, 0006814=sodium ion transport" 0016021=integral component of membrane "ppk26, pickpocket 26, balboa, bba, CG8546" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG8546 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" "WBGene00003174(mec-10),WBGene00003168(mec-4),WBGene00000950(deg-1),WBGene00012137(asic-2)" "ENSXETG00000022398(ACCN5),ENSXETG00000013366(ACCN3),ENSXETG00000014229(ACCN1)" "ENSMUSG00000020704(Accn1),ENSMUSG00000023017(Accn2),ENSMUSG00000038276(Accn3),ENSMUSG00000033007(Accn4),ENSMUSG00000028008(Accn5)" "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" "partially lethal - majority die,some die during pupal stage,viable" FBgn0032987 RpL21 Ribosomal protein L21 http://flybase.net/reports/FBgn0032987.html "FBan0012775, FBgn0026278, FBgn0064845" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "BcDNA:RH06526, CG12775, anon-EST:Posey18, RPL21, anon-EST:Posey30, Rp L21" "IPR018259=Ribosomal protein L21e, conserved site, IPR008991=Translation protein SH3-like domain, IPR001147=Ribosomal protein L21e" CG12775 16-Dec-15 2015_12 ENSDARG00000010516(rpl21) "YBR191W(RPL21A),YPL079W(RPL21B)" WBGene00004433(rpl-21) ENSXETG00000009802(rpl21) "ENSMUSG00000061115(Gm10095),ENSMUSG00000041453(Rpl21),ENSMUSG00000066443(Gm10163),ENSMUSG00000068397(Gm10240),ENSMUSG00000058640(Gm10045),ENSMUSG00000061684(Rpl21-ps8),ENSMUSG00000066180(Gm10155),ENSMUSG00000071077(Gm9104),ENSMUSG00000064315(Rpl21-ps10),ENSMUSG00000061242(Rpl21-ps7),ENSMUSG00000056777,ENSMUSG00000056849(Gm16415),ENSMUSG00000062152(Rpl21-ps14),ENSMUSG00000060566(Rpl21-ps3),ENSMUSG00000069986(Gm8054),ENSMUSG00000057370(Rpl21-ps12),ENSMUSG00000078125,ENSMUSG00000059483(Rpl21-ps1),ENSMUSG00000060125(Gm5528),ENSMUSG00000063162(Gm16416),ENSMUSG00000071475(Rpl21-ps5),ENSMUSG00000078224(Gm6919),ENSMUSG00000060899(Rpl21-ps11),ENSMUSG00000059912(Rpl21-ps6),ENSMUSG00000078917,ENSMUSG00000072714(Rpl21-ps4)" "ENSG00000122026(RPL21),ENSG00000214760" lethal DRSC03704 EK -0.058292519 -0.888829945 0.875920913 -5.127087486 0.870875276 3.196471541 FBgn0031855 CG11221 http://flybase.net/reports/FBgn0031855.html protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation PKN "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG11221 16-Dec-15 2015_12 "ENSDARG00000021660(bsk146),ENSDARG00000031618(LOC557524),ENSDARG00000056294(LOC559792),ENSDARG00000013548(LOC791840),ENSDARG00000058944(LOC100001826),ENSDARG00000020455(LOC566942),ENSDARG00000057687(zgc:172086)" WBGene00015293(C01C4.3) "ENSXETG00000012254(),ENSXETG00000010325(SBK1),ENSXETG00000016923(),ENSXETG00000019143(SBK2),ENSXETG00000008802(),ENSXETG00000018197()" "ENSMUSG00000042978(Sbk1),ENSMUSG00000030433(Sbk2)" "ENSG00000188322(SBK1),ENSG00000187550(SBK2)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036764 CG5535 http://flybase.net/reports/FBgn0036764.html FBgn0062237 protein_coding_gene "0015174=basic amino acid transmembrane transporter activity, 0015171=amino acid transmembrane transporter activity" "0006865=amino acid transport, 0003333=amino acid transmembrane transport" 0016020=membrane anon-WO0118547.111 "IPR029485=Cationic amino acid transporter, C-terminal, IPR002293=Amino acid/polyamine transporter I" CG5535 16-Dec-15 2015_12 "ENSDARG00000016439(LOC559627),ENSDARG00000037097(slc7a2),ENSDARG00000071661,ENSDARG00000020645(slc7a3),ENSDARG00000061566(LOC100003376)" "YEL063C(CAN1),YFL055W(AGP3),YBR069C(TAT1),YNL270C(ALP1),YNL268W(LYP1),YDR508C(GNP1),YCL025C(AGP1),YDR046C(BAP3),YBR068C(BAP2),YKR039W(GAP1),YOL020W(TAT2),YGR191W(HIP1),YPL274W(SAM3),YPL265W(DIP5),YLL061W(MMP1),YOR348C(PUT4),YBR132C(AGP2),YDR160W(SSY1)" "ENSXETG00000005526(SLC7A3),ENSXETG00000000683(SLC7A2),ENSXETG00000015899(),ENSXETG00000005504(SLC7A1)" "ENSMUSG00000031297(Slc7a3),ENSMUSG00000031596(Slc7a2),ENSMUSG00000054753(AU018091),ENSMUSG00000041313(Slc7a1)" "ENSG00000165349(SLC7A3),ENSG00000003989(SLC7A2),ENSG00000139514(SLC7A1)" "viable,visible" trichogen cell FBgn0034025 GalNAc-T1 GalNAc-T1 http://flybase.net/reports/FBgn0034025.html protein_coding_gene 0004653=polypeptide N-acetylgalactosaminyltransferase activity 0009312=oligosaccharide biosynthetic process 0005795=Golgi stack "CG8182, polypeptide GalNAc transferase 1, N-acetylgalactosaminyltransferase, pgant1" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR000772=Ricin B, lectin domain, IPR001173=Glycosyltransferase 2-like" CG8182 16-Dec-15 2015_12 WBGene00012934(gly-9) "viable,fertile" FBgn0030345 CG1847 http://flybase.net/reports/FBgn0030345.html protein_coding_gene 0017162=aryl hydrocarbon receptor binding 0006457=protein folding "IPR013026=Tetratricopeptide repeat-containing domain, IPR023114=Elongated TPR repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain, IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain" CG1847 16-Dec-15 2015_12 "ENSDARG00000005937,ENSDARG00000069699(aip),ENSDARG00000014095(LOC100002619)" WBGene00016966(C56C10.10) "ENSXETG00000017438(aip),ENSXETG00000006821(AIPL1)" "ENSMUSG00000024847(Aip),ENSMUSG00000040554(Aipl1)" "ENSG00000110711(AIP),ENSG00000129221(AIPL1)" viable FBgn0035436 CG12016 http://flybase.net/reports/FBgn0035436.html protein_coding_gene 0050262=ribosylnicotinamide kinase activity "0019359=nicotinamide nucleotide biosynthetic process, 0046495=nicotinamide riboside metabolic process" 0005737=cytoplasm Dromel_CG12016_FBtr0073063_mORF "IPR026681=Nicotinamide riboside kinase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG12016 16-Dec-15 2015_12 "ENSDARG00000037913(zgc:113113),ENSDARG00000071677,ENSDARG00000071681,ENSDARG00000041427(LOC100329645),ENSDARG00000042931(mibp2),ENSDARG00000067848(zgc:103408)" YNL129W(NRK1) ENSXETG00000022049(itgb1bp3) "ENSMUSG00000037847(BC016495),ENSMUSG00000004939(Itgb1bp3)" "ENSG00000106733(C9orf95),ENSG00000077009(ITGB1BP3)" viable DRSC08224 K -1.100866548 -0.127186471 -0.161024089 -1.440469696 1.356219706 2.321001171 FBgn0052320 CG32320 http://flybase.net/reports/FBgn0052320.html protein_coding_gene 0016021=integral component of membrane IPR012858=Dendritic cell-specific transmembrane protein-like CG32320 16-Dec-15 2015_12 ENSDARG00000018957 WBGene00007117(spe-42) "ENSXETG00000005468(),ENSXETG00000003334()" ENSG00000163354(DCST2) FBgn0037902 CG5281 http://flybase.net/reports/FBgn0037902.html protein_coding_gene 0016021=integral component of membrane IPR000620=EamA domain CG5281 16-Dec-15 2015_12 ENSDARG00000063268 "YMR253C(),YPL264C()" ENSXETG00000003728(TMEM20) ENSMUSG00000044026(Tmem20) ENSG00000176273(SLC35G1) viable FBgn0004854 B-H2 BarH2 http://flybase.net/reports/FBgn0004854.html protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0001751=compound eye photoreceptor cell differentiation, 0007479=leg disc proximal/distal pattern formation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0008052=sensory organ boundary specification, 0046331=lateral inhibition, 0008407=chaeta morphogenesis, 0007455=eye-antennal disc morphogenesis, 0008057=eye pigment granule organization" 0005634=nucleus "BH2, Bar-H2, B, Bar, BarH2, CG5488, bar-h2, Barh2, BarH" "IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG5488 16-Dec-15 2015_12 "ENSDARG00000070129(barhl2),ENSDARG00000019013(barhl1.1),ENSDARG00000035508(barhl1.2)" WBGene00006873(vab-7) "ENSXETG00000023986(BARHL2),ENSXETG00000006257(BARHL1)" "ENSMUSG00000034384(Barhl2),ENSMUSG00000026805(Barhl1)" "ENSG00000143032(BARHL2),ENSG00000125492(BARHL1)" embryonic stage " neuron

, embryonic central nervous system

, peripheral nervous system

, external sensory organ

, thecogen cell

" " pupal stage | >20 hr , embryonic stage , larval stage | late -- P | early " " primary pigment cell

, neuron

, thecogen cell

, embryonic central nervous system

, photoreceptor cell R6 | presumptive

, external sensory organ

, peripheral nervous system

" "visible,recessive,body color defective,partially lethal - majority die,some die during pupal stage" "scutellum,wing,adult head,scutellum & microchaeta,wing & microchaeta,microchaeta & head capsule & adult,microchaeta,ectopic,prescutum & macrochaeta,tarsal segment 3,tarsal segment 4,pretarsus,ventral thoracic disc,morphogenetic furrow,photoreceptor cell,leg,eye,chaeta,supernumerary,mesothoracic tergum" FBgn0051712 CG31712 http://flybase.net/reports/FBgn0051712.html FBgn0032165 protein_coding_gene CG5879 CG31712 16-Dec-15 2015_12 "ENSDARG00000018319(arglu1b),ENSDARG00000019223(arglu1a)" ENSXETG00000025471(Q6P2W5_XENTR) ENSMUSG00000040459(Arglu1) ENSG00000134884(ARGLU1) viable FBgn0029006 Smurf SMAD specific E3 ubiquitin protein ligase http://flybase.net/reports/FBgn0029006.html "FBgn0034252, FBgn0041185" protein_coding_gene "0005515=protein binding, 0004842=ubiquitin-protein transferase activity" "0048619=embryonic hindgut morphogenesis, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0040008=regulation of growth, 0007293=germarium-derived egg chamber formation, 0010629=negative regulation of gene expression, 0007179=transforming growth factor beta receptor signaling pathway, 0001700=embryonic development via the syncytial blastoderm, 0030514=negative regulation of BMP signaling pathway, 0008101=decapentaplegic signaling pathway" "0000151=ubiquitin ligase complex, 0005737=cytoplasm, 0005634=nucleus" "Smurf1, CG4943, d-smurf, Dsmurf, lack, Lack, D-smurf, LACK, DSmurf, Smurf ubiquitin ligase, Smurf, dSmurf, lethal with a checkpoint kinase, dSmurf1, smurf, SMURF" "IPR000008=C2 domain, IPR000569=HECT domain, IPR001202=WW domain" CG4943 16-Dec-15 2015_12 "ENSDARG00000016086(wwp1),ENSDARG00000038067(smurf2)" ENSXETG00000007498(SMURF1) "ENSMUSG00000038780(Smurf1),ENSMUSG00000018363(Smurf2)" "ENSG00000108854(SMURF2),ENSG00000198742(SMURF1)" "viable,fertile,lethal,rescuable maternal effect,lethal - all die before end of P-stage,some die during pharate adult stage,partially,visible,recessive,somatic clone,body color defective" "embryonic/first instar larval cuticle,rescuable maternal effect,embryonic head,amnioserosa,embryonic hindgut,stomodeum,dorsal,wing,leg,eye,somatic clone,mesothoracic tergum" DRSC07641 E 0.777610595 0.837193219 1.677739866 -1.155367533 0.183854375 0.006576088 FBgn0029935 CG4615 http://flybase.net/reports/FBgn0029935.html protein_coding_gene "0022008=neurogenesis, 0019835=cytolysis, 0006909=phagocytosis" 0016021=integral component of membrane "IPR004254=AdipoR/Haemolysin-III-related, IPR005744=Hly-III" CG4615 16-Dec-15 2015_12 ENSDARG00000040387 ENSXETG00000004315(MMD) "ENSMUSG00000039533(Mmd2),ENSMUSG00000003948(Mmd)" "ENSG00000108960(MMD),ENSG00000136297(MMD2)" "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" DRSC26722 K 0.156996644 -0.265364741 0.28377132 -0.231610732 -1.023384634 -1.612059664 FBgn0024365 CG12773 http://flybase.net/reports/FBgn0024365.html protein_coding_gene "0008511=sodium:potassium:chloride symporter activity, 0015171=amino acid transmembrane transporter activity" 0003333=amino acid transmembrane transport 0016021=integral component of membrane EG:8D8.3 "IPR030343=Solute carrier family 12 member 8, IPR004841=Amino acid permease/ SLC12A domain" CG12773 16-Dec-15 2015_12 WBGene00017350(F10E7.9) ENSMUSG00000035506(Slc12a8) ENSG00000221955(SLC12A8) viable FBgn0264000 GluRIB Glutamate receptor IB http://flybase.net/reports/FBgn0264000.html "FBgn0028431, FBgn0035972, FBgn0260235" protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0005230=extracellular ligand-gated ion channel activity, 0004970=ionotropic glutamate receptor activity" 0006812=cation transport 0008328=ionotropic glutamate receptor complex "DmelGlu-R1B, Glu-R1B, dglur-IB, CG4481, CG43743, GluRIB, GluRIb, DGluR-IB, CG42509, Glu-RIB, Dm_3L:43677, glutamate receptor" "IPR028082=Periplasmic binding protein-like I, IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001828=Receptor, ligand binding region" CG43743 16-Dec-15 2015_12 "ENSDARG00000052765(gria2b),ENSDARG00000070173(gria2a),ENSDARG00000059368(gria4b),ENSDARG00000037498(gria3b),ENSDARG00000021352(gria1a),ENSDARG00000032737(gria3a),ENSDARG00000032714(gria1b),ENSDARG00000021104" "WBGene00001612(glr-1),WBGene00001613(glr-2)" "ENSXETG00000001922(GRIA1),ENSXETG00000019504(GRIA3)" "ENSMUSG00000033981(Gria2),ENSMUSG00000025892(Gria4),ENSMUSG00000001986(Gria3),ENSMUSG00000020524(Gria1)" "ENSG00000120251(GRIA2),ENSG00000152578(GRIA4),ENSG00000125675(GRIA3),ENSG00000155511(GRIA1)" FBgn0036703 CG7707 http://flybase.net/reports/FBgn0036703.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0019005=SCF ubiquitin ligase complex FBXO8 CG7707 16-Dec-15 2015_12 "WBGene00007838(fbxa-168),WBGene00007837(fbxa-167),WBGene00015600(fbxa-165),WBGene00045289(fbxa-169),WBGene00007162(fbxa-153),WBGene00007166(fbxa-152),WBGene00044661(fbxa-143),WBGene00022890(fbxa-224),WBGene00015602(fbxa-158),WBGene00009838(fbxa-187),WBGene00045295(fbxa-222),WBGene00012566(fbxa-211),WBGene00044758(Y37H2A.12),WBGene00012565(fbxa-210),WBGene00021178(Y9C9A.8),WBGene00012953(fbxa-216),WBGene00015598(fbxa-163),WBGene00007163(fbxa-154),WBGene00022217(fbxa-221),WBGene00008014(fbxa-172),WBGene00012879(fbxa-215),WBGene00015601(fbxa-166),WBGene00009840(fbxa-189),WBGene00009836(fbxa-185),WBGene00009837(fbxa-186),WBGene00044659(fbxa-142),WBGene00013610(fbxa-206),WBGene00009839(fbxa-188),WBGene00011513(fbxa-197),WBGene00018439(fbxa-184),WBGene00044655(fbxa-194),WBGene00007453(fbxa-98),WBGene00015362(fbxa-105),WBGene00013757(fbxa-113),WBGene00021390(fbxa-214),WBGene00008015(fbxa-174),WBGene00020890(fbxa-202)" viable FBgn0028434 Ercc1 Ercc1 http://flybase.net/reports/FBgn0028434.html protein_coding_gene "0000014=single-stranded DNA endodeoxyribonuclease activity, 0005515=protein binding, 0046982=protein heterodimerization activity, 0003684=damaged DNA binding" "0006296=nucleotide-excision repair, DNA incision, 5'-to lesion, 0007131=reciprocal meiotic recombination, 0000712=resolution of meiotic recombination intermediates, 0006289=nucleotide-excision repair, 0048812=neuron projection morphogenesis" "0043234=protein complex, 0005634=nucleus" "CG10215, ERCC1" "IPR004579=ERCC1/RAD10/SWI10 family, IPR011335=Restriction endonuclease type II-like, IPR010994=RuvA domain 2-like" CG10215 16-Dec-15 2015_12 ENSDARG00000031680(ercc1) YML095C(RAD10) WBGene00008665(ercc-1) ENSXETG00000026094(ERCC1) ENSMUSG00000003549(Ercc1) ENSG00000012061(ERCC1) "radiation sensitive,chemical sensitive,viable" DRSC07424 IE -1.614653627 -1.390085814 1.576430677 -1.938030547 0.599051948 1.138399138 FBgn0030082 HP1b Heterochromatin Protein 1b http://flybase.net/reports/FBgn0030082.html protein_coding_gene 0003682=chromatin binding "0045944=positive regulation of transcription from RNA polymerase II promoter, 0031452=negative regulation of heterochromatin assembly, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0000792=heterochromatin, 0005634=nucleus, 0005719=nuclear euchromatin, 0010369=chromocenter" "Heterochromatin Protein 1B, Hp1b, HP1, CG7041, HP1B, HP1b" "IPR023780=Chromo domain, IPR023779=Chromo domain, conserved site, IPR017984=Chromo domain subgroup, IPR000953=Chromo/chromo shadow domain, IPR016197=Chromo domain-like, IPR008251=Chromo shadow domain" CG7041 16-Dec-15 2015_12 "ENSDARG00000003860(cbx3a),ENSDARG00000004189(cbx1a),ENSDARG00000054442(cbx1b)" WBGene00001995(hpl-1) "ENSXETG00000012175(CBX3),ENSXETG00000021962(cbx1),ENSXETG00000021279(cbx5)" "ENSMUSG00000018666(Cbx1),ENSMUSG00000059647,ENSMUSG00000029836(Cbx3),ENSMUSG00000009575(Cbx5),ENSMUSG00000074843(Gm6901)" "ENSG00000108468(CBX1),ENSG00000122565(CBX3),ENSG00000094916(CBX5)" "partially lethal - majority die,viable,lethal" FBgn0030362 regucalcin regucalcin http://flybase.net/reports/FBgn0030362.html protein_coding_gene 0032504=multicellular organism reproduction "0005615=extracellular space, 0005576=extracellular region, 0005811=lipid particle" "T1, CG1803, Regucalcin" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR005511=Senescence marker protein-30 (SMP-30), IPR013658=SMP-30/Gluconolactonase/LRE-like region" CG1803 16-Dec-15 2015_12 "ENSDARG00000071154,ENSDARG00000071147,ENSDARG00000071137,ENSDARG00000032200(rgn)" ENSXETG00000004127(Q6DF62_XENTR) ENSMUSG00000023070(Rgn) ENSG00000130988(RGN) "viable,fertile,lethal" FBgn0030659 CG9215 http://flybase.net/reports/FBgn0030659.html protein_coding_gene "0008270=zinc ion binding, 0003676=nucleic acid binding" 0005634=nucleus "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG9215 16-Dec-15 2015_12 "ENSDARG00000071720,ENSDARG00000071723,ENSDARG00000071714(si:dkey-20i20.5),ENSDARG00000071712,ENSDARG00000071713,ENSDARG00000071719(si:dkey-20i20.2),ENSDARG00000071716,ENSDARG00000071846,ENSDARG00000071812,ENSDARG00000071811(si:dkey-4c15.6),ENSDARG00000071829,ENSDARG00000071838,ENSDARG00000071819,ENSDARG00000071791,ENSDARG00000071792,ENSDARG00000052346,ENSDARG00000021484,ENSDARG00000071767(LOC100150655),ENSDARG00000071815(LOC100150260),ENSDARG00000071580,ENSDARG00000040146,ENSDARG00000071833,ENSDARG00000044847(zgc:171599),ENSDARG00000022905,ENSDARG00000071820,ENSDARG00000071858,ENSDARG00000071725(zgc:174919),ENSDARG00000038478(LOC100150696)" WBGene00010770(K11D2.4) viable DRSC20171 I -0.060953914 -2.263476935 -1.311423958 -1.473586256 0.098476968 -0.674986586 FBgn0003071 Pfk Phosphofructokinase http://flybase.net/reports/FBgn0003071.html FBgn0010618 protein_coding_gene "0003872=6-phosphofructokinase activity, 0005524=ATP binding" "0009744=response to sucrose, 0006002=fructose 6-phosphate metabolic process, 0007520=myoblast fusion, 0007525=somatic muscle development, 0006096=glycolytic process" "0005945=6-phosphofructokinase complex, 0005737=cytoplasm" "CG4001, l(2)06339, PFK1, BcDNA.GH12192, phosphofructokinase, PFK, Phosphofructokinase 1, pfk, BcDNA:GH12192, 6-phosphofructokinase" "IPR022953=ATP-dependent 6-phosphofructokinase, IPR009161=ATP-dependent 6-phosphofructokinase, eukaryotic-type, IPR015912=Phosphofructokinase, conserved site, IPR000023=Phosphofructokinase domain" CG4001 16-Dec-15 2015_12 "ENSDARG00000028000(LOC560944),ENSDARG00000012801(LOC561416),ENSDARG00000014179(pfkma),ENSDARG00000060797(pfkmb),ENSDARG00000060504(LOC570106)" "YMR205C(PFK2),YGR240C(PFK1)" WBGene00022199(Y71H10A.1) "ENSXETG00000007279(PFKM),ENSXETG00000021922(pfkp)" "ENSMUSG00000033065(Pfkm),ENSMUSG00000020277(Pfkl),ENSMUSG00000021196(Pfkp)" "ENSG00000152556(PFKM),ENSG00000067057(PFKP),ENSG00000141959(PFKL)" embryonic stage -- adult stage larval stage--adult stage "lethal,recessive,viable" "embryonic/larval somatic muscle,embryonic myoblast" FBgn0085377 CG34348 http://flybase.net/reports/FBgn0085377.html "FBgn0030288, FBgn0040852" protein_coding_gene "0016746=transferase activity, transferring acyl groups" 0008152=metabolic process "CG11757, CG15197" IPR002123=Phospholipid/glycerol acyltransferase CG34348 16-Dec-15 2015_12 WBGene00021394(Y38C1AA.1) ENSXETG00000005647(TEgg109d16.1) ENSMUSG00000028232(Tmem68) ENSG00000167904(TMEM68) viable FBgn0037475 Fer1 48 related 1 http://flybase.net/reports/FBgn0037475.html "FBgn0037476, FBgn0053323, FBgn0063658" protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "BcDNA:RH30329, CG14611, CG33323, fer1, bHLHa30, CG10066" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG33323 16-Dec-15 2015_12 ENSDARG00000014479(ptf1a) WBGene00003018(lin-32) ENSXETG00000005914(PTF1A) ENSMUSG00000026735(Ptf1a) ENSG00000168267(PTF1A) viable FBgn0015316 Try29F Trypsin 29F http://flybase.net/reports/FBgn0015316.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP106, CG9564, try29F.2, try29F" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG9564 16-Dec-15 2015_12 "ENSDARG00000052517(LOC560086),ENSDARG00000055011(LOC565163)" "ENSXETG00000007733(BC087610.1),ENSXETG00000025357(BC087759.1),ENSXETG00000016566(BC087563.1),ENSXETG00000007734(),ENSXETG00000007732(BC089741.1),ENSXETG00000019241(BC075423.1),ENSXETG00000004320(BC088079.1),ENSXETG00000019309(BC087830.1),ENSXETG00000019305(),ENSXETG00000024870(BC088011.1),ENSXETG00000002940(BC087753.1)" "ENSMUSG00000057163(Prss2),ENSMUSG00000054106(Try4),ENSMUSG00000062751(Prss1),ENSMUSG00000071521(Try10),ENSMUSG00000071517(Gm10334),ENSMUSG00000071519(Prss3),ENSMUSG00000058119(Gm5771),ENSMUSG00000036938(Try5),ENSMUSG00000059014(Gm5409),ENSMUSG00000029882(2210010C04Rik),ENSMUSG00000036996(1810009J06Rik),ENSMUSG00000063252" "ENSG00000204982,ENSG00000204983(PRSS1),ENSG00000010438(PRSS3)" embryonic stage | stage 16-17 embryonic/larval midgut | posterior

"viable,visible" trichogen cell FBgn0264922 smt3 smt3 http://flybase.net/reports/FBgn0264922.html "FBgn0026170, FBgn0010577, FBgn0025539, FBgn0069078, FBgn0065910" protein_coding_gene 0005515=protein binding "0046843=dorsal appendage formation, 0016926=protein desumoylation, 0009952=anterior/posterior pattern specification, 0035073=pupariation, 0007052=mitotic spindle organization, 0055088=lipid homeostasis, 0006606=protein import into nucleus, 0071560=cellular response to transforming growth factor beta stimulus, 0006099=tricarboxylic acid cycle, 0060997=dendritic spine morphogenesis, 0043406=positive regulation of MAP kinase activity, 0035186=syncytial blastoderm mitotic cell cycle, 0046579=positive regulation of Ras protein signal transduction, 0021952=central nervous system projection neuron axonogenesis, 0006909=phagocytosis, 0006464=cellular protein modification process, 0016925=protein sumoylation" "0005634=nucleus, 0000780=condensed nuclear chromosome, centromeric region, 0030496=midbody, 0000940=condensed chromosome outer kinetochore, 0000794=condensed nuclear chromosome, 0005730=nucleolus" "CG4494, Dm0342, lethal (2) SH0182, anon-EST:Posey240, Smt3, Small Ubiquitin-like Modifier, SUMO protein, dsmt3, l(2)04493, Sumo, DmSmt3, sumo, Dmsmt3, SMT3, DmSUMO-1, SUMO, dSmt3, l(2)SH0182, l(2)SH2 0182" "IPR029071=Ubiquitin-related domain, IPR022617=Rad60/SUMO-like domain, IPR000626=Ubiquitin domain" CG4494 16-Dec-15 2015_12 "ENSDARG00000046062(sumo2),ENSDARG00000035993(sumo3),ENSDARG00000028119(sumo3l)" YDR510W(SMT3) WBGene00004888(smo-1) "ENSXETG00000027487(SUMO2),ENSXETG00000012516(SUMO3)" "ENSMUSG00000020265(Sumo3),ENSMUSG00000020738(Sumo2)" "ENSG00000177688(SUMO4),ENSG00000184900(SUMO3)" embryonic stage && larval stage && adult stage embryonic stage " cell

, organism

" DRSC03611 IK 0.986455357 2.195064602 0.494406179 -0.926324009 1.551299802 0.091238662 FBgn0036336 ste14 isoprenylcysteine carboxylmethyltransferase http://flybase.net/reports/FBgn0036336.html protein_coding_gene 0004671=protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 0006481=C-terminal protein methylation "0016021=integral component of membrane, 0005783=endoplasmic reticulum" "Ste14, CG11268, Dmel\Ste14, ste14" "IPR007269=Isoprenylcysteine carboxyl methyltransferase, IPR025770=Protein-S-isoprenylcysteine O-methyltransferase" CG11268 16-Dec-15 2015_12 ENSDARG00000020241(icmt) YDR410C(STE14) "WBGene00017673(F21F3.3),WBGene00019710(M01E11.1)" ENSXETG00000002918(ICMT) ENSMUSG00000039662(Icmt) ENSG00000116237(ICMT) viable FBgn0020312 CG4050 http://flybase.net/reports/FBgn0020312.html FBgn0015361 protein_coding_gene 0016262=protein N-acetylglucosaminyltransferase activity 0017122=protein N-acetylglucosaminyltransferase complex "anon-DM192, anon-j" "IPR001440=Tetratricopeptide repeat 1, IPR013618=Domain of unknown function DUF1736, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat" CG4050 16-Dec-15 2015_12 ENSDARG00000062846(tmtc3) ENSXETG00000011736(TMTC3) ENSMUSG00000036676(Tmtc3) ENSG00000139324(TMTC3) "partially lethal - majority die,some die during pupal stage" FBgn0030286 CG1657 http://flybase.net/reports/FBgn0030286.html protein_coding_gene "0017112=Rab guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity, 0032794=GTPase activating protein binding" "0032483=regulation of Rab protein signal transduction, 0051223=regulation of protein transport, 0043087=regulation of GTPase activity" 0005829=cytosol "IPR001936=Ras GTPase-activating protein, IPR003123=VPS9 domain, IPR008936=Rho GTPase activation protein" CG1657 16-Dec-15 2015_12 ENSDARG00000041920 WBGene00004377(rme-6) ENSXETG00000005493(GAPVD1) ENSMUSG00000026867(Gapvd1) ENSG00000165219(GAPVD1) "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC19752 E 0.493572631 1.130857766 1.773524148 0.128008496 0.251698482 0.51142775 FBgn0046704 Liprin-ë± Liprin-ë± http://flybase.net/reports/FBgn0046704.html "FBgn0024747, FBgn0031852, FBgn0061489" protein_coding_gene 0005515=protein binding "0007412=axon target recognition, 0008594=photoreceptor cell morphogenesis, 0007416=synapse assembly, 0045467=R7 cell development, 0048675=axon extension, 0007411=axon guidance, 0097479=synaptic vesicle localization, 0048841=regulation of axon extension involved in axon guidance, 0048490=anterograde synaptic vesicle transport, 0031290=retinal ganglion cell axon guidance, 0051124=synaptic growth at neuromuscular junction" "0043234=protein complex, 0045202=synapse, 0048786=presynaptic active zone, 0005925=focal adhesion" "liprin-alpha, DLiprin-alpha, Liprin, CG11199, dliprin-alpha, Liprin-alpha, out of step, oos, LIP, lip-alpha, LAR-interacting protein 1, Dliprin, LIP.1, Liprin-a, LIP1, DLiprin, lpr, Dliprin-alpha" "IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain, IPR030442=Liprin-alpha, IPR029515=LAR-interacting protein, Liprin" CG11199 16-Dec-15 2015_12 "ENSDARG00000013000(si:ch211-107n23.1),ENSDARG00000053205(ppfia4)" WBGene00006364(syd-2) "ENSXETG00000003798(PPFIA1),ENSXETG00000000265(PPFIA3)" "ENSMUSG00000053825(Ppfia2),ENSMUSG00000026458(Ppfia4),ENSMUSG00000003863(Ppfia3)" "ENSG00000131626(PPFIA1),ENSG00000139220(PPFIA2),ENSG00000143847(PPFIA4),ENSG00000177380(PPFIA3)" " embryonic stage , larval stage , embryonic stage | stage 4-17 " " embryonic peripheral nervous system

, ventral nerve cord

, embryonic/larval somatic muscle

, larval central nervous system

, embryonic central nervous system

, embryonic brain

" " larval stage , embryonic stage | stage 16,17 " " neuromuscular junction

, synapse

, neuropil ventral nerve cord

, larval central nervous system

" "neuroanatomy defective,neurophysiology defective,somatic clone,lethal,partially lethal - majority die,recessive,male sterile" "neuromuscular junction,bouton,embryonic/larval neuromuscular junction,synaptic vesicle,optic cartridge,somatic clone,eye photoreceptor cell,photoreceptor cell R7,cell non-autonomous,photoreceptor cell R4,medulla,NMJ bouton" FBgn0032236 mRpS7 mitochondrial ribosomal protein S7 http://flybase.net/reports/FBgn0032236.html protein_coding_gene "0003735=structural constituent of ribosome, 0003723=RNA binding" 0006412=translation "0005763=mitochondrial small ribosomal subunit, 0022627=cytosolic small ribosomal subunit" "CG5108, RpS7, MRP-S7, mRPS7" "IPR023798=Ribosomal protein S7 domain, IPR000235=Ribosomal protein S5/S7" CG5108 16-Dec-15 2015_12 ENSDARG00000042077(mrps7) YJR113C(RSM7) WBGene00013324(Y57G11C.34) ENSXETG00000012510(MRPS7) ENSMUSG00000046756(Mrps7) ENSG00000125445(MRPS7) "viable,visible" trichogen cell FBgn0025456 CREG Cellular Repressor of E1A-stimulated Genes http://flybase.net/reports/FBgn0025456.html FBgn0064909 protein_coding_gene "0016491=oxidoreductase activity, 0042803=protein homodimerization activity, 0010181=FMN binding, 0008134=transcription factor binding" "0055114=oxidation-reduction process, 0000122=negative regulation of transcription from RNA polymerase II promoter" "cellular repressor of E1A-stimulated genes, creg, BcDNA:LP11958, CG5413, dCREG" "IPR014631=Cellular repressor of E1A-stimulated genes (CREG), IPR012349=FMN-binding split barrel" CG5413 16-Dec-15 2015_12 ENSDARG00000000666(creg2) ENSXETG00000023010(creg1) "ENSMUSG00000040713(Creg1),ENSMUSG00000050967(Creg2)" "ENSG00000143162(CREG1),ENSG00000175874(CREG2)" viable FBgn0004896 fd59A forkhead domain 59A http://flybase.net/reports/FBgn0004896.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003690=double-stranded DNA binding, 0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0048846=axon extension involved in axon guidance, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007389=pattern specification process, 0048484=enteric nervous system development, 0048485=sympathetic nervous system development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048937=lateral line nerve glial cell development, 0009888=tissue development, 0007422=peripheral nervous system development, 0051090=regulation of sequence-specific DNA binding transcription factor activity" "0005634=nucleus, 0005667=transcription factor complex" "CG3668, FD59A, fd3, fd59a, foxd, Fd59a, Dmfd3, FD3" "IPR001766=Fork head domain, IPR018122=Fork head domain conserved site1, IPR011991=Winged helix-turn-helix DNA-binding domain" CG3668 16-Dec-15 2015_12 "ENSMUSG00000067261(Foxd3),ENSMUSG00000078302(Foxd1),ENSMUSG00000055210(Foxd2)" embryonic stage " larval thoracic sensillum | precursor

, ventral midline

, neuroblast

, embryonic brain

" "viable,semi-fertile" FBgn0035872 CG7185 http://flybase.net/reports/FBgn0035872.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding, 0003729=mRNA binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0006379=mRNA cleavage" "0005849=mRNA cleavage factor complex, 0005634=nucleus" "cg7185, CFlm-68k, CF I[[m]]68" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG7185 16-Dec-15 2015_12 ENSDARG00000018618(cpsf6) WBGene00008362(cfim-2) ENSXETG00000001439(CPSF6) ENSMUSG00000055531(Cpsf6) ENSG00000111605(CPSF6) viable DRSC10781 I -0.63160175 -2.38956706 -1.073407435 -0.08736464 -0.749360006 -0.177486969 FBgn0034487 Efhc1.2 EFHC1 homologue 2 http://flybase.net/reports/FBgn0034487.html protein_coding_gene 0042384=cilium assembly "Defhc1.2, CG11048, EFHC1 homolog" "IPR006602=Uncharacterised domain DM10, IPR010554=Protein of unknown function DUF1126" CG11048 16-Dec-15 2015_12 ENSDARG00000004204(efhc2) WBGene00013028(Y49A10A.1) ENSXETG00000000659(Q66IK9_XENTR) ENSMUSG00000025038(Efhc2) ENSG00000183690(EFHC2) "viable,fertile" FBgn0036480 Cep135 http://flybase.net/reports/FBgn0036480.html protein_coding_gene 0008017=microtubule binding "0007099=centriole replication, 0032053=ciliary basal body organization, 0051297=centrosome organization, 0007288=sperm axoneme assembly, 0046331=lateral inhibition, 0007026=negative regulation of microtubule depolymerization, 0055059=asymmetric neuroblast division, 0007100=mitotic centrosome separation" "0005813=centrosome, 0036064=ciliary basal body, 0005814=centriole" "bld10, CG17081, Bld-10, DCep135/Bld10, Bld10p, DmBLD10, CEP135, Cep135, DCep135, dbld10, Bld10" CG17081 16-Dec-15 2015_12 ENSDARG00000002991 WBGene00015356(tag-278) ENSXETG00000021069(CEP135) "ENSMUSG00000036403(Cep135),ENSMUSG00000060771(Tsga10)" "ENSG00000174799(CEP135),ENSG00000135951(TSGA10)" "female fertile,male sterile,recessive,viable,meiotic cell cycle defective,male,visible" "spermatozoon,primary spermatocyte,centriole | progressive,spermatid axoneme,centrioleBrd15),interphase microtubule organizing centerBrd15),neuroblast,mitotic spindleBrd15),centrioleED218),chaeta" FBgn0033657 Sln Silnoon http://flybase.net/reports/FBgn0033657.html protein_coding_gene "0015355=secondary active monocarboxylate transmembrane transporter activity, 0008028=monocarboxylic acid transmembrane transporter activity" "0015718=monocarboxylic acid transport, 0055085=transmembrane transport" "0016324=apical plasma membrane, 0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0016323=basolateral plasma membrane" CG8271 "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG8271 16-Dec-15 2015_12 "YOR306C(MCH5),YOL119C(MCH4)" "increased cell death,small body,lethal - all die before end of larval stage,some die during larval stage,viable" wing disc FBgn0041181 Tep3 Thioester-containing protein 3 http://flybase.net/reports/FBgn0041181.html FBgn0031933 protein_coding_gene 0004866=endopeptidase inhibitor activity "0098542=defense response to other organism, 0006909=phagocytosis, 0050830=defense response to Gram-positive bacterium" 0005615=extracellular space "TEP3mel, Tep3, TEPIII, TEP, CG7068, TepIII, TEP3, Thiolester containing protein III, dTEPIII" "IPR011626=Alpha-macroglobulin complement component, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048=Alpha-macroglobulin, receptor-binding, IPR019565=Alpha-2-macroglobulin, thiol-ester bond-forming, IPR011625=Alpha-2-macroglobulin, N-terminal 2, IPR019742=Alpha-2-macroglobulin, conserved site, IPR002890=Alpha-2-macroglobulin, N-terminal, IPR001599=Alpha-2-macroglobulin" CG7068 16-Dec-15 2015_12 "ENSDARG00000056314(a2ml),ENSDARG00000041645(sb:cb37),ENSDARG00000041685(LOC100006782),ENSDARG00000056588,ENSDARG00000024892,ENSDARG00000017289,ENSDARG00000017619,ENSDARG00000041639,ENSDARG00000035291,ENSDARG00000053178,ENSDARG00000027924,ENSDARG00000035292,ENSDARG00000041653,ENSDARG00000058274,ENSDARG00000008835" WBGene00013969(ZK337.1) "ENSXETG00000024219(BC093458.1),ENSXETG00000024227(),ENSXETG00000017070(),ENSXETG00000006980(BC091705.1),ENSXETG00000006979(),ENSXETG00000009402(),ENSXETG00000017401(),ENSXETG00000009400()" ENSMUSG00000046186(Cd109) ENSG00000156535(CD109) "viable,fertile,immune response defective" DRSC03452 E 0.113856801 -0.701503109 3.343495256 0.977988176 0.490349447 0.107022181 FBgn0002643 mam mastermind http://flybase.net/reports/FBgn0002643.html "FBgn0010581, FBgn0026797" protein_coding_gene 0003713=transcription coactivator activity "0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0035019=somatic stem cell maintenance, 0007418=ventral midline development, 0008407=chaeta morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008356=asymmetric cell division, 0048749=compound eye development, 0030718=germ-line stem cell maintenance, 0007399=nervous system development, 0008587=imaginal disc-derived wing margin morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0007398=ectoderm development, 0003007=heart morphogenesis, 0007219=Notch signaling pathway, 0007500=mesodermal cell fate determination" "0005703=polytene chromosome puff, 0005700=polytene chromosome, 0016607=nuclear speck, 0005634=nucleus" "SR2-4, Mam, l(2)04615, N-2G, master mind, MAM, Dm0064, dMam, l(2)03505, Mastermind, CG8118, mam(CAG)[[7]]" "IPR019082=Neurogenic mastermind-like, N-terminal" CG8118 16-Dec-15 2015_12 " embryonic stage | gastrula , adult stage && oogenesis stage | stage S10 , larval stage | late , larval stage , pupal stage | early , embryonic stage | 2-16 hr , embryonic stage | gastrula | early , embryonic stage | cellular blastoderm , embryonic stage | stage 13-17 , embryonic stage | contracted germ band , embryonic stage | stage 8 , embryonic stage | 8-16 hr , embryonic stage | extended germ band , embryonic stage | stage 6 , embryonic stage | stage 6-8 , embryonic stage | 0-2 hr , embryonic stage | 16 hr , embryonic stage | stage 13 , adult stage && oogenesis stage | early , embryonic stage | 5 hr " " anterior midgut proper primordium

, follicle cell

, dorsal mesothoracic disc

, endoderm | presumptive

,

ubiquitous , ventral nerve cord

, cephalic furrow

, oocyte

, inclusive hindgut primordium

, nurse cell

, mesoderm | presumptive

, ventral thoracic disc

, ectoderm | ventral

, germ band

, central nervous system | restricted

, eye-antennal disc

, morphogenetic furrow | anterior to

, mesectoderm

, ventral furrow

, ventral neurogenic region | restricted

, larval brain

, posterior midgut proper primordium

, embryonic/larval digestive system | rudiment

, embryonic/larval foregut

, ventral midline

, ventral nerve cord | segmentally repeated pattern

" " larval stage | third instar , embryonic stage | stage 17 , embryonic stage | stage 14-15 , embryonic stage | stage 9-17 , embryonic stage | stage 8 , embryonic stage | stage 11 , embryonic stage | stage >8 , embryonic stage | stage 7-8 , adult stage && oogenesis stage , embryonic stage | stage 9-10 , embryonic stage | gastrula , embryonic stage | blastoderm , embryonic stage | stage 14-17 " " neuroblast

, embryonic/larval hindgut

, central nervous system

, optic lobe

, embryonic/larval salivary gland

, ventral neurogenic region

, inclusive hindgut primordium

, mesoderm

, mesectoderm

, antenno-maxillary complex | restricted

, epidermis

, ventral midline

, dorsal mesothoracic disc

, embryonic/larval hindgut | presumptive

, ventral nerve cord | restricted

, embryonic/larval esophagus

, embryonic/larval midgut

, follicle cell

, Malpighian tubule

, neuroblast MP2

, anterior midgut proper primordium

, ectoderm

, cephalic furrow

, subesophageal ganglion

, embryonic/larval foregut

, embryonic/larval proventriculus

, eye-antennal disc

, posterior midgut proper primordium

,

ubiquitous , larval brain

, embryonic/larval pharynx

, ventral nerve cord

, ventral thoracic disc

, epidermis

lateral & dorsal " "visible,dominant,neuroanatomy defective,lethal,recessive,viable,fertile,lethal - all die before end of embryonic stage,neurogenic phenotype,some die during embryonic stage,somatic clone,male sterile,female sterile,partially lethal - majority die,chemical sensitive,homeotic,heat sensitive" "wing,posterior midline glial cell,midline glial cell,supernumerary,embryo,germline clone,maternal effect,VUM motorneuron,VUM interneuron,H-cell sib,H-cell,neuroblast MNB,presumptive embryonic/larval central nervous system,embryonic/larval cuticle,vMP2 neuron,RP2sib neuron,pCC neuron,segmental nerve,intersegmental nerve,anterior fascicle & synapse | supernumerary,germline cell,male,RP2 motor neuron,ectopic,anterior,wing vein L3,wing vein L5,presumptive embryonic/larval peripheral nervous system,olfactory receptor neuron,antennal lobe glomerulus DL4,adult olfactory receptor neuron Or49a/85f,antennal lobe glomerulus VL1,antennal lobe glomerulus VM4,antennal lobe glomerulus VC3l,antennal lobe glomerulus VM1,antennal lobe glomerulus VC3,antennal lobe glomerulus VC1,antennal lobe glomerulus VA4,antennal lobe glomerulus VC2,antennal lobe glomerulus VC4,antennal lobe glomerulus DL1,antennal lobe glomerulus DM1,antennal lobe glomerulus V,antennal lobe glomerulus DM4,antennal lobe glomerulus DM2,antennal lobe glomerulus DM3,antennal lobe glomerulus DA4l,antennal lobe glomerulus DC1,antennal lobe glomerulus DA3,antennal lobe glomerulus DA1,wing vein,eye,macrochaeta,U neuron,wing vein L2,wing vein L4,ventral nerve cord,embryonic/larval somatic muscle,embryonic/larval dorsal vessel,precursor,nervous system,heart primordium,ectoderm,embryonic epidermis,dorsal cluster neuron,medulla,stomatogastric nervous system primordium,ventral,lateral,somatic clone,ommatidium,eye photoreceptor cell,pigment cell,cuticle & macrochaeta | somatic clone,interommatidial bristle,trichogen cell,tormogen cell,thecogen cell,wing margin,ovary,multidendritic neuron,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,lateral ventral subperineurial glial cell,presumptive embryonic/larval nervous system,embryonic myoblast,egg chamber,follicle stem cell,embryonic labral segment & embryonic epidermis,embryonic labial segment & embryonic epidermis,embryonic hypopharynx & epidermis,embryonic maxillary segment & embryonic epidermis,larval head,denticle belt,aCC neuron,dMP2 neuron,Usib neuron,neuroblast,microchaeta,tendon cell,antenna,morphogenetic furrow,wing margin bristle,scutellar bristle,notopleural bristle,posterior notopleural bristle,heat sensitive,female germline stem cell,germarium cap cell,embryonic/larval neuron,sensory mother cell,mesothoracic tergum,apterous-expressing neuron of the lateral cluster of the thorax,embryonic heart cardioblast,embryonic pericardial cell" FBgn0039141 spas spastin http://flybase.net/reports/FBgn0039141.html protein_coding_gene "0008568=microtubule-severing ATPase activity, 0005524=ATP binding, 0016887=ATPase activity, 0008017=microtubule binding" "2000331=regulation of terminal button organization, 0000070=mitotic sister chromatid segregation, 1900074=negative regulation of neuromuscular synaptic transmission, 0000226=microtubule cytoskeleton organization, 0007626=locomotory behavior, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0050775=positive regulation of dendrite morphogenesis, 0019226=transmission of nerve impulse, 0031117=positive regulation of microtubule depolymerization, 0045834=positive regulation of lipid metabolic process, 1900075=positive regulation of neuromuscular synaptic transmission, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0051013=microtubule severing, 0048167=regulation of synaptic plasticity, 0035099=hemocyte migration" "0005737=cytoplasm, 0005813=centrosome, 0043195=terminal bouton, 0031594=neuromuscular junction, 0008021=synaptic vesicle, 0005694=chromosome" "Spastin, spastin, CG5977, Dm-Spastin, Dspastin, Spas, spasin, D-spastin" "IPR007330=MIT, IPR017179=Spastin, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR015415=Vps4 oligomerisation, C-terminal, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site" CG5977 16-Dec-15 2015_12 ENSDARG00000024933(spast) YPL074W(YTA6) ENSXETG00000011392(spast) ENSMUSG00000024068(Spast) ENSG00000021574(SPAST) wandering third instar larval stage NMJ bouton "neuroanatomy defective,somatic clone,visible,viable,fertile,short lived,partially lethal - majority die,flight defective,behavior defective,neurophysiology defective,sterile,flightless,locomotor behavior defective,eclosion defective,heat stress response defective,stress response defective,some die during pupal stage,lethal - all die before end of pupal stage,uncoordinated,majority die during pupal stage,gravitaxis defective,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,cell polarity defective" "ventral nerve cord,dendritic arborizing neuron,somatic clone,eye,border follicle cell,embryonic/larval neuromuscular junction | third instar larval stage,adult brain,morphogenetic furrow,embryonic/larval muscle system | larval stage,microtubule | larval stagehow-24B,bouton,leg,eye photoreceptor cell,NMJ bouton,microtubule,class IV dendritic arborizing neuron,dorsal multidendritic neuron ddaC,dendrite,supernumerary,microtubule | larval stage,synapse | third instar larval stageelav.PU,microtubuleelav.PU,bouton | third instar larval stage,cytoplasmic microtubule,neuromuscular junction | larval stage,dendriteppk.PG,embryonic/larval neuromuscular junction,embryonic/larval neuromuscular junction | larval stage,brain | adult stage,somatic muscle & microtubuleG14,class I dendritic arborizing neuron,dorsal multidendritic neuron ddaE,dendriteppk.1.9,microtubuleppk.1.9,microtubuleC57,microtubulesrp.Hemo,cytoskeletonsrp.Hemo,hemocyte" DRSC15929 IE 2.38373763 0.75372683 2.210430347 -0.064869408 -0.311043066 0.141796464 FBgn0014343 mirr mirror http://flybase.net/reports/FBgn0014343.html "FBgn0013332, FBgn0013561, FBgn0013593, FBgn0016017, FBgn0017368, FBgn0020310" protein_coding_gene "0042803=protein homodimerization activity, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity" "0097374=sensory neuron axon guidance, 0045317=equator specification, 0007476=imaginal disc-derived wing morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0046843=dorsal appendage formation, 0001700=embryonic development via the syncytial blastoderm, 0007422=peripheral nervous system development, 0007224=smoothened signaling pathway, 0045893=positive regulation of transcription, DNA-templated, 0001745=compound eye morphogenesis" 0005634=nucleus "Sail, crep, IRO-C, crepuscule, MIRR, De3, Mirr, cre, mir, mrr, Iroquis complex, iroquois, l(3)6D1, l(3)69Da, DH1, unnamed, CG10601, caupalican, IroC, Mirror, De1, Iro-C, Iro, Mrr, Group F, Iroquois, iro-C, Sai, l(3)69Ca, group F, l(3)A5-3-42, iro" "IPR003893=Iroquois-class homeodomain protein, IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR008422=Homeobox KN domain" CG10601 16-Dec-15 2015_12 "ENSDARG00000035648(irx4a),ENSDARG00000036051(irx4b)" ENSXETG00000008892(Q688D0_XENTR) "ENSMUSG00000031737(Irx5),ENSMUSG00000031734(Irx3),ENSMUSG00000060969(Irx1),ENSMUSG00000001504(Irx2)" "ENSG00000113430(IRX4),ENSG00000159387(IRX6)" " embryonic stage | stage 13 , larval stage | third instar , embryonic stage -- adult stage , larval stage , embryonic stage | stage 10 , adult stage && oogenesis stage , embryonic stage | stage >5 " " embryonic/larval proventriculus

, presutural bristle | precursor

, dorsal mesothoracic disc | restricted

, imaginal disc | restricted

, neuroblast

, follicle cell | restricted

, dorsal fold

, eye-antennal disc | dorsal <&> anterior

, eye-antennal disc | dorsal

, embryo | dorsal

, organism | segmentally repeated

, ventral nerve cord

, sensory mother cell

, embryo | anterior & ventral

, postalar bristle | precursor

" "locomotor behavior defective,neuroanatomy defective,lethal,recessive,visible,viable,partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage,maternal effect,lethal - all die before end of larval stage,some die during larval stage,planar polarity defective,somatic clone,some die during first instar larval stage,dominant,cell non-autonomous,some die during pupal stage" "abdominal ventral multidendritic neuron vdaB,germarium,egg operculum,egg chamber,dorsal appendage,alula,macrochaeta & adult thorax,wing,chorion,anterior postalar bristle,posterior supraalar bristle,ommatidium,maternal effect,scutellar bristle,haltere,chorion | anterior | maternal effect,embryo,somatic clone,eye equator,ectopic,eye,dorsal,scutum,dendrite,presutural bristle,antennal disc,posterior,postalar bristle,tergite,cell autonomous,dorsal margin photoreceptor,denticle belt,embryonic abdominal segment,eye disc,follicle cell,embryonic/larval thoracic/abdominal ventral sensory cluster,dendritescE1x6,egg,trichogen cell" FBgn0029687 Vap-33A VAMP-associated protein of 33kDa ortholog A http://flybase.net/reports/FBgn0029687.html "FBgn0025953, FBgn0040184, FBgn0062492, FBgn0066853" protein_coding_gene "0031122=cytoplasmic microtubule organization, 0050829=defense response to Gram-negative bacterium, 0007269=neurotransmitter secretion, 0072553=terminal button organization, 0008088=axon cargo transport, 0007528=neuromuscular junction development, 0060074=synapse maturation, 0016082=synaptic vesicle priming, 0046488=phosphatidylinositol metabolic process" "0005811=lipid particle, 0012505=endomembrane system, 0005886=plasma membrane, 0005789=endoplasmic reticulum membrane, 0005615=extracellular space, 0005783=endoplasmic reticulum, 0008021=synaptic vesicle" "dVAP, dVAP33A, l(1)G0231, anon-EST:Liang-2.42, vap-33A, VAP, VAP33-A, dvap33a, DVAP33A, VAP-33-1, VAMP-associated protein of 33kDa A, anon-WO03040301.124, DVAP-33A, VAPB, CG5014, BcDNA:GM03307, vap33-1, clone 2.42, DVAP, Vap33-1, Vap-33-1, VAP-33" "IPR016763=Vesicle-associated membrane-protein-associated protein, IPR008962=PapD-like, IPR000535=Major sperm protein (MSP) domain" CG5014 16-Dec-15 2015_12 "ENSDARG00000070435(vapb),ENSDARG00000046048(vapal)" "YBL091C-A(SCS22),YER120W(SCS2)" WBGene00018008(vpr-1) ENSXETG00000004038(vapa) "ENSMUSG00000054455(Vapb),ENSMUSG00000024091(Vapa),ENSMUSG00000046487(Mospd4)" "ENSG00000124164(VAPB),ENSG00000101558(VAPA)" "neuroanatomy defective,majority die during pupal stage,locomotor rhythm defective,viable,visible,lethal - all die before end of larval stage,some die during larval stage,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,recessive,neurophysiology defective,uncoordinated,increased cell death,flight defective,fertile,partially lethal - majority die,male,female,heat sensitive,size defective" "terminal bouton,neuromuscular junction,microtubule,nucleus,synapse,synapseC57,nucleusC57,somatic muscle,eye,photoreceptor cell,ommatidium,NMJ bouton,macrochaeta,bouton,mushroom body alpha-lobe,wing disc,endoplasmic reticulumC5,trichogen cell,mesothoracic tergum,NMJ bouton | larval stage,indirect flight muscle,synapseC164,bouton & microtubuleC164,bouton & microtubule,interommatidial bristle,supernumerary,eye photoreceptor cell,endoplasmic reticulumelav.PU,endoplasmic reticulumC57" FBgn0002413 dco discs overgrown http://flybase.net/reports/FBgn0002413.html "FBgn0011349, FBgn0011508, FBgn0024895, FBgn0027967, FBgn0028129" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0016301=kinase activity, 0005524=ATP binding, 0005515=protein binding" "0030307=positive regulation of cell growth, 0016310=phosphorylation, 0045475=locomotor rhythm, 0008062=eclosion rhythm, 0045732=positive regulation of protein catabolic process, 0007555=regulation of ecdysteroid secretion, 0030431=sleep, 0043066=negative regulation of apoptotic process, 0042067=establishment of ommatidial planar polarity, 0046777=protein autophosphorylation, 0048148=behavioral response to cocaine, 0007623=circadian rhythm, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0042752=regulation of circadian rhythm, 0007622=rhythmic behavior, 0006468=protein phosphorylation, 0042306=regulation of protein import into nucleus, 0007446=imaginal disc growth, 0001737=establishment of imaginal disc-derived wing hair orientation, 0016055=Wnt signaling pathway, 0051781=positive regulation of cell division, 0007154=cell communication" "0005737=cytoplasm, 0005634=nucleus, 0005886=plasma membrane" "DOUBLETIME, CK1epsilon, DCO/CKIe, dco-1, 0538/13, l(3)S053813, double-time, Dbt, Casein kinase I epsilon, CKIepsilon, dbt, Dco, l(3)dco-1, DOUBLE-TIME, dCKIepsilon, doubletime, l(3)discs overgrown-1, Casein Kinase I epsilon, ddbt, disc overgrown, Double-time, 1447/01, DBT, l(3)dco, CG2048, 1460/09, 0915/10, CK1delta/epsilon, Double time, l(3)j3B9, DBT/CK1epsilon, l(3)discs overgrown, DCO, Double-Time, ck1epsilon, Discs overgrown, l(3)S144701, double time, 1396/02, l(3)rK215, Casein Kinase Iepsilon, Doubletime, Dco/CK1" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG2048 16-Dec-15 2015_12 "ENSDARG00000006125(csnk1db),ENSDARG00000008370(csnk1da),ENSDARG00000045150(csnk1e)" YPL204W(HRR25) WBGene00002203(kin-20) "ENSXETG00000006357(csnk1e),ENSXETG00000001288(csnk1d)" "ENSMUSG00000022433(Csnk1e),ENSMUSG00000025162(Csnk1d)" "ENSG00000213923(CSNK1E),ENSG00000141551(CSNK1D)" adult stage " adult lateral neuron

, photoreceptor cell

, adult brain | restricted

" "viable,size defective,fertile,circadian rhythm defective,cell polarity defective,lethal,recessive,locomotor rhythm defective,eclosion rhythm defective,cell size defective,somatic clone,cell autonomous,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,temperature conditional,partially lethal - majority die,visible,hyperplasia,wild-type,polyphasic,increased cell number,semidominant,partially lethal - majority live,behavior defective,cell death defective,flight defective,dominant,partially lethal" "wing,class IV dendritic arborizing neuron,somatic clone,ommatidium,neuron,lateral,wing disc,wing hair,cell non-autonomous,cell autonomous,crossvein,larva,imaginal disc,wing pouch,eye,vibrissae,wing vein,tarsal segment,adult external head,leg,unguis,supernumerary,larval head,dorsal organ,terminal organ,labral segment,embryonic/larval cuticle,dorsal,dorsal bridge,egg,germline clone,eye photoreceptor cell,wing margin bristle,trichogen cell,mesothoracic tergum" DRSC16929 I 1.989390382 1.027456985 0.858794289 0.581831233 -0.192138506 0.221942657 FBgn0001079 fu fused http://flybase.net/reports/FBgn0001079.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005515=protein binding, 0005524=ATP binding" "0042073=intraciliary transport, 0031398=positive regulation of protein ubiquitination, 0042993=positive regulation of transcription factor import into nucleus, 0007224=smoothened signaling pathway, 0030514=negative regulation of BMP signaling pathway, 0007367=segment polarity determination, 0006468=protein phosphorylation, 0031647=regulation of protein stability, 0030162=regulation of proteolysis, 0007293=germarium-derived egg chamber formation, 0007228=positive regulation of hh target transcription factor activity" "0005737=cytoplasm, 0043234=protein complex, 0035301=Hedgehog signaling complex, 0016020=membrane" "fu[mel], FU, l(1)fu, CG6551, Dm fu, dFu, Fused, Fu" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG6551 16-Dec-15 2015_12 ENSG00000163482(STK36) " adult stage , adult stage | female , embryonic stage | <= stage 11 , embryonic stage | early , larval stage " " egg chamber | subset

, organism

,

ubiquitous , germarium region 2

, imaginal disc

" adult stage " germarium region 2

, egg chamber | subset

" "visible,recessive,viable,female fertile,reduced,wild-type,tumorigenic,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,female semi-sterile,germline clone,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,somatic clone,segment polarity phenotype,hyperplasia,heat sensitive" "wing,anterior compartment,sensillum campaniformium,ectopic,wing vein,1st posterior cell,double row,wing vein L3,wing vein L4,wing basal cell 2,dil cell,egg,germline clone,embryo,ovary,denticle belt,maternal effect,embryonic ventral nervous system,blastoderm embryo,embryonic segment,proximal,Bolwig organ,germline cell,cell non-autonomous,somatic clone,posterior compartment,oocyte,egg chamber,cystoblast,supernumerary,ocellar bristle,interocellar bristle,lateral ocellus,medial ocellus,ovariole,distal,microchaeta & tarsal segment 1,microchaeta & tarsal segment 2,microchaeta & tarsal segment 3,microchaeta & tarsal segment 4,microchaeta & tarsal segment 5,macrochaeta & tarsal segment 5 | distal,mesothoracic tarsal bristle longitudinal row 4,mesothoracic tarsal bristle longitudinal row 3.5,mesothoracic tarsal bristle longitudinal row 1,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 8,mesothoracic tarsal bristle longitudinal row 2.5,wing sensillum,dorsal double row,ventral double row,sensillum campaniformium of dorsal radius,anterior crossvein,embryonic epidermis,ocellus,anterior scutellar bristle,scutellum,embryonic thorax,embryonic abdomen,interfollicle cell,polar follicle cell,nurse cell,presumptive embryonic/larval central nervous system,posterior cell,wing basal cell 1,posterior scutellar bristle,dorsal hair,segment,posterior,germarium,female germline cell" DRSC20333 I 0.490788449 -2.434819276 0.442541585 0.657667334 -0.476184012 0.097666183 FBgn0001965 Sos Son of sevenless http://flybase.net/reports/FBgn0001965.html "FBgn0013235, FBgn0026802" protein_coding_gene "0003677=DNA binding, 0030676=Rac guanyl-nucleotide exchange factor activity, 0046982=protein heterodimerization activity, 0005088=Ras guanyl-nucleotide exchange factor activity, 0005515=protein binding" "0045500=sevenless signaling pathway, 0016199=axon midline choice point recognition, 0046579=positive regulation of Ras protein signal transduction, 0008360=regulation of cell shape, 0035023=regulation of Rho protein signal transduction, 0035022=positive regulation of Rac protein signal transduction, 0008293=torso signaling pathway, 0008595=anterior/posterior axis specification, embryo, 0007426=tracheal outgrowth, open tracheal system, 0007265=Ras protein signal transduction, 0007480=imaginal disc-derived leg morphogenesis, 0007399=nervous system development, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0007015=actin filament organization" "0005737=cytoplasm, 0031234=extrinsic component of cytoplasmic side of plasma membrane" "l(2)br25, lethal 24 in the black-reduced region, dSos, son-of-sevenless, lethal 25 in the black-reduced region, Su(tor)2-2, sos, EY2-3, CG7793, SOS, l(2)Sos, l(2)br24, Sos1, 2.3, l(2)k05224, BG:DS00941.4, br25, E(var)189, son of sevenless, br24, 34Ea, dme-SOS, EK2-8, l(2)34Ea, EC2-5, E(sev)2A, Son-of-sevenless, l(2)k06321" "IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019804=Ras guanine-nucleotide exchange factor, conserved site, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000219=Dbl homology (DH) domain, IPR001849=Pleckstrin homology domain, IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR023578=Ras guanine nucleotide exchange factor domain" CG7793 16-Dec-15 2015_12 ENSDARG00000060506(sos2) WBGene00004947(sos-1) "ENSXETG00000009131(SOS2),ENSXETG00000008386(SOS1)" "ENSMUSG00000034801(Sos2),ENSMUSG00000024241(Sos1)" "ENSG00000100485(SOS2),ENSG00000115904(SOS1)" "visible,viable,fertile,recessive,lethal,enhancer of variegation,dominant,wild-type,mitotic cell cycle defective,cell autonomous,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,terminal phenotype,germline clone,maternal effect,body color defective" "wing,wing vein,photoreceptor cell R7,ommatidium,somatic clone,dorsal air sac primordium,pCC neuron,dMP2 neuron,vMP2 neuron,longitudinal connective,eye,ectopic,macrochaeta,commissure,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R8,eye disc,cell autonomous,midline crossing tract,embryo,germline clone,maternal effect,wing vein L4,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC03439 IEK -2.867508031 -6.526072224 -3.167020634 -3.67134216 -1.435347178 -2.484029732 FBgn0010341 Cdc42 Cdc42 http://flybase.net/reports/FBgn0010341.html FBgn0012059 protein_coding_gene "0032794=GTPase activating protein binding, 0003924=GTPase activity, 0005515=protein binding, 0019901=protein kinase binding, 0005525=GTP binding" "0007409=axonogenesis, 0035010=encapsulation of foreign target, 0007391=dorsal closure, 0030707=ovarian follicle cell development, 0007010=cytoskeleton organization, 0010592=positive regulation of lamellipodium assembly, 0031532=actin cytoskeleton reorganization, 0007179=transforming growth factor beta receptor signaling pathway, 0007286=spermatid development, 0072659=protein localization to plasma membrane, 0016192=vesicle-mediated transport, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0046843=dorsal appendage formation, 0048813=dendrite morphogenesis, 0007396=suture of dorsal opening, 0051491=positive regulation of filopodium assembly, 0042060=wound healing, 0030031=cell projection assembly, 0050975=sensory perception of touch, 0030833=regulation of actin filament polymerization, 0031175=neuron projection development, 0007254=JNK cascade, 0007015=actin filament organization, 0030041=actin filament polymerization, 0007411=axon guidance, 0007274=neuromuscular synaptic transmission, 0035099=hemocyte migration, 0045200=establishment of neuroblast polarity, 0007349=cellularization, 0046664=dorsal closure, amnioserosa morphology change, 0007266=Rho protein signal transduction, 0008582=regulation of synaptic growth at neuromuscular junction, 0030011=maintenance of cell polarity, 0008045=motor neuron axon guidance, 0035011=melanotic encapsulation of foreign target, 0030036=actin cytoskeleton organization, 0030866=cortical actin cytoskeleton organization, 0006909=phagocytosis, 0090303=positive regulation of wound healing, 0051601=exocyst localization, 0035318=imaginal disc-derived wing hair outgrowth, 0008360=regulation of cell shape, 0060446=branching involved in open tracheal system development, 0097206=nephrocyte filtration, 0048477=oogenesis, 0050770=regulation of axonogenesis" "0016028=rhabdomere, 0005634=nucleus, 0005737=cytoplasm, 0030426=growth cone, 0030424=axon, 0005938=cell cortex, 0045177=apical part of cell" "Cdc42Dm, Dm Cdc42, D-cdc42, CG12530, Dcdc42, Cdc42-like, DmCDC42, P40793, D-CDC42, CDC42, DCDC42, DCdc42, D-Cdc42, cdc42, Dmcdc42" "IPR003578=Small GTPase superfamily, Rho type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG12530 16-Dec-15 2015_12 "ENSDARG00000070182,ENSDARG00000044573(cdc42),ENSDARG00000042240" YLR229C(CDC42) WBGene00000390(cdc-42) ENSXETG00000004743(cdc42) ENSMUSG00000006699(Cdc42) ENSG00000070831(CDC42) " embryonic stage | stage 10-12 , embryonic stage , embryonic stage | blastoderm , embryonic stage -- adult stage " " somatic mesoderm

, embryonic central nervous system

, embryonic/larval digestive system

,

ubiquitous " "male sterile,wild-type,visible,lethal,recessive,cell shape defective,planar polarity defective,somatic clone,wound healing defective,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,neuroanatomy defective,cell polarity defective,decreased cell size,viable,size defective,immune response defective,non-rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,touch sensitivity defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,female,partially lethal - majority die,neurophysiology defective,chemical sensitive,chemical resistant" "spermatid cyst,seminal vesicle,head cyst cell,actin filamentT155,nurse cell,eye,ommatidium,photoreceptor,pigment cell,rhabdomere,interommatidial bristle,anterior crossvein,ectopic,follicle cell,somatic clone,wing,crossvein,embryo,maternal effect,nurse cell ring canal,germline clone,actin filament | germline clone | maternal effect,vertical system neuron,oocyte,dendrite | ectopic,dendritic spine,axon,terminal tracheal cell,eye photoreceptor cell,retina,embryonic/larval pericardial cell,dorsal closure embryo,embryonic epidermis,ventral,embryonic/first instar larval cuticle,anterior,presumptive embryonic/larval central nervous system,longitudinal connective,embryonic hemocyte,macrophage,nurse cell & actin filament | germ-line clone | maternal effect,proventriculus inner layer primordium,proventriculus intermediate layer primordium,embryonic proventriculus,ganglionic branch primordium,neuroblast,wing hair,supernumerary,actin filament & rhabdomere | somatic clone,neuromuscular junction,bouton,embryonic/larval neuromuscular junction,NMJ bouton,microchaeta & wingptc-559.1,wing disc,anterior/posterior compartment boundary,dorsal,embryonic hemocyte & leading edgePxn.PS, crq.PA,embryonic/larval dorsal trunk,embryonic/larval somatic muscle,myotube,muscle attachment site,microchaeta,wing vein,wing margin,wing margin bristle,heat sensitive,medial triple row,cell non-autonomous,presumptive embryonic/larval tracheal system,antenna & glial cellMz317,antenna & sensory neuronMz317,embryonic/larval midgut | embryonic stage,dorsal appendage,abdominal segmental nerve,neuroblast | embryonic stage,neuromuscular junctionMhc.Switch.PO,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3,neuron,abdominal posterior fascicle neuron & growth cone & filopodiumelav.PLu,mesothoracic les3 neuron & growth cone & filopodiumelav.PLu,metathoracic les3 neuron & growth cone & filopodiumelav.PLu,dendrite | dorsal | embryonic stage60,presumptive embryonic/larval peripheral nervous system,dorsal multidendritic neuron | embryonic stage,dorsal multidendritic neuron & dendrite & embryo60,abdominal intersegmental nerve,dorsal abdominal cluster,dendrite,somatic muscle,antennal commissure,antennal lobe glomerulus,glomerulus,mesothoracic leg disc,aCC neuron & dendriteeve.RN2,RP2 neuron & dendriteeve.RN2,RP2 motor neuron,RP2 neuron & neuriteeve.RN2,RP2 neuron & cell bodyeve.RN2,pCC neuron,dMP2 neuron,vMP2 neuron,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,macrochaeta & metathoracic laterotergiteBx-MS1096,microchaeta & metathoracic laterotergiteBx-MS1096,motor neuron,growth coneelav.PLu,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,giant fiber neuron,eye disc,growth cone,neurite,giant axon,anterior embryonic/larval midgut,aCC neuron,neuromuscular junctionC57,epithelium,female germline cyst" FBgn0260442 rhea rhea http://flybase.net/reports/FBgn0260442.html "FBgn0020254, FBgn0035910" protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005178=integrin binding, 0005158=insulin receptor binding, 0051015=actin filament binding, 0003779=actin binding, 0005515=protein binding" "0006909=phagocytosis, 0007016=cytoskeletal anchoring at plasma membrane, 0008360=regulation of cell shape, 0007390=germ-band shortening, 0045214=sarcomere organization, 0035160=maintenance of epithelial integrity, open tracheal system, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0033627=cell adhesion mediated by integrin, 0007430=terminal branching, open tracheal system, 0060439=trachea morphogenesis, 0007526=larval somatic muscle development, 0007298=border follicle cell migration, 0045892=negative regulation of transcription, DNA-templated, 0016203=muscle attachment, 0007155=cell adhesion" "0005856=cytoskeleton, 0005925=focal adhesion, 0001726=ruffle" "Tln, CT21159, CG6831, tendrils, talin, Rhea, Talin" "IPR006077=Vinculin/alpha-catenin, IPR018979=FERM, N-terminal, IPR029071=Ubiquitin-related domain, IPR015009=Vinculin-binding site-containing domain, IPR002558=I/LWEQ domain, IPR002404=IRS-type PTB domain, IPR019748=FERM central domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019747=FERM conserved site, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR015224=Talin, central, IPR019749=Band 4.1 domain, IPR000299=FERM domain" CG6831 16-Dec-15 2015_12 " embryonic stage | stage 12 , embryonic stage | stage 6 , embryonic stage | stage 16 " " ventral nervous system

, organism | ubiquitous

, embryonic midgut

, muscle attachment site

" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 16 , embryonic stage | stage 6 " " anterior midgut proper primordium && posterior midgut proper primordium

, dorsal mesothoracic disc | restricted

, muscle attachment site

,

" "viable,lethal,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "egg chamber,conditional,muscle attachment site,germline clone,presumptive embryonic/larval muscle system,muscle cell,tendon cell,muscle cell & actin filament & embryo,tendon cell & microtubule & embryo,muscle cell & focal adhesion & embryo,tendon cell & focal adhesion & embryo,tendon cell & basal lamina & embryo,somatic clone,actin filament & follicle cell | somatic clone,embryonic/larval midgut primordium,embryonic proventriculus,germ band,rescuable maternal effect,terminal tracheal cell,oocyte,cell non-autonomous,gastric caecum primordium,wing,embryonic/larval somatic muscle,eye,embryonic/larval tracheal system,embryonic/larval fat body branch,border follicle cell" FBgn0000022 ac achaete http://flybase.net/reports/FBgn0000022.html protein_coding_gene "0046982=protein heterodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0007417=central nervous system development, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0007422=peripheral nervous system development, 0048477=oogenesis, 0007400=neuroblast fate determination, 0061382=Malpighian tubule tip cell differentiation, 0045893=positive regulation of transcription, DNA-templated, 0007346=regulation of mitotic cell cycle, 0002805=regulation of antimicrobial peptide biosynthetic process, 0007419=ventral cord development, 0008407=chaeta morphogenesis, 0007423=sensory organ development" "0005634=nucleus, 0005667=transcription factor complex" "Hairy-wing, Ac, sc/T5, T5, ASC, achete, AS-C T5, 990 E5 F1, EG:125H10.3, CG3796, asc, achaete-scute, AC, AS-C, AS-C T5ac, Acheate, Hw, Hairy wing, ascT5, Achaete/Scute, Achaete" "IPR015660=Achaete-scute transcription factor-related, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG3796 16-Dec-15 2015_12 "ENSDARG00000038386(ascl1a),ENSDARG00000009702(ascl1b)" WBGene00001958(hlh-14) "ENSMUSG00000020052(Ascl1),ENSMUSG00000009248(Ascl2)" "ENSG00000139352(ASCL1),ENSG00000183734(ASCL2)" " embryonic stage , larval stage , embryonic stage | stage 9 , larval stage | third instar , embryonic stage | stage 8 " " stomodeum

, neuroblast

, sensory mother cell

, posterior embryonic/larval midgut

, proneural cluster

, embryonic stomatogastric nervous system

, neuroblast

{ $ N* } , neurogenic region

, neurectoderm

{ $ E(spl)* } , sensory organ cell

, dorsal mesothoracic disc | restricted

, ventral midline

, ectoderm

, procephalic segment

, larval optic lobe | presumptive

, procephalic neuroblast

, embryonic central nervous system

, dorsal mesothoracic disc

, neurectoderm

{ $ Dl* } , neurectoderm

{ $ neur* } , cephalic furrow

, embryonic peripheral nervous system

, labral segment

, ventral neurogenic region

, neurectoderm

{ $ bib* } " " larval stage | third instar , larval stage , embryonic stage | stage 9-11 , embryonic stage | stage 8-9 , embryonic stage , embryonic stage | stage 8 , embryonic stage | stage 8-10 , embryonic stage | stage 8-11 , embryonic stage | stage 9 , wandering third instar larval stage " " dorsal mesothoracic disc

, sensory mother cell

, protocerebral neuroblast | subset

, neuroblast NB3-5

, neurectoderm

{ $ neur* } , proneural cluster

, neurectoderm

{ $ bib* } , neuroblast NB7-4

, wing vein L5

, ectoderm

, deuterocerebral neuroblast | subset

, neuroblast NB7-1

, neuroblast MP2

, procephalic neuroblast | subset

, wing vein L1

{ + h* } , ventral neurogenic region

, wing vein L3

{ + h* } , procephalic neurogenic region | restricted

, neuroblast

{ $ N* } , neurectoderm

{ $ E(spl)* } , neurectoderm

{ $ Dl* } , dorsal mesothoracic disc | dorsal/ventral compartment boundary & restricted " "visible,dominant,recessive,viable,good,wild-type,male sterile,fertile,male fertile,female sterile" "external sensory organ,ectopic,scutellum,wing vein L3,macrochaeta & head,macrochaeta & thorax,sensillum campaniformium,microchaeta,mesothoracic tarsal bristle,mesothoracic metatarsus,macrochaeta,glial cell,wing & nerve,nerve,third segment of antenna,mesothoracic tergum & macrochaeta | ectopic,wing margin bristle,anterior orbital bristle,anterior notopleural bristle,humeral bristle,postvertical bristle,ocellar bristle,presutural bristle,anterior postalar bristle,anterior supraalar bristle,posterior postalar bristle,posterior supraalar bristle,scutellar bristle,dorsocentral bristle,acrostichal bristle,supernumerary,anterior dorsocentral bristle,posterior dorsocentral bristle,microchaeta & mesothoracic pleurum,microchaeta & wing,macrochaeta & abdominal tergite,microchaeta & pleural membrane,interocellar bristle,interommatidial bristle,mesothoracic leg sensillum,posterior notopleural bristle,microchaeta & scutum,microchaeta & scutellum,sensillum campaniformium of proximal dorsal radius,sense organ & wing vein,precursor,macrochaeta & leg,microchaeta & leg,adult thorax & microchaeta,scutum,wing,microchaeta & mesothoracic tergum | supernumerary,neuron,anterior sternopleural bristle,wing vein,posterior crossvein,chaeta,sensory mother cell,sensory mother cell & dorsal mesothoracic disc" DRSC18734 I -1.740211892 -2.639558744 0.435517917 1.190294363 0.396568427 0.114040713 FBgn0026404 Dronc Death regulator Nedd2-like caspase http://flybase.net/reports/FBgn0026404.html "FBgn0025326, FBgn0062102" protein_coding_gene "0097199=cysteine-type endopeptidase activity involved in apoptotic signaling pathway, 0042803=protein homodimerization activity, 0050700=CARD domain binding, 0004175=endopeptidase activity, 0004197=cysteine-type endopeptidase activity" "0006919=activation of cysteine-type endopeptidase activity involved in apoptotic process, 0035234=ectopic germ cell programmed cell death, 0008340=determination of adult lifespan, 0045476=nurse cell apoptotic process, 0007423=sensory organ development, 0035071=salivary gland cell autophagic cell death, 0031638=zymogen activation, 0007516=hemocyte development, 0010623=developmental programmed cell death, 2001269=positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, 0048749=compound eye development, 0016322=neuron remodeling, 0046672=positive regulation of compound eye retinal cell programmed cell death, 0010941=regulation of cell death, 0007417=central nervous system development, 0048102=autophagic cell death, 0048813=dendrite morphogenesis, 0035070=salivary gland histolysis, 0001700=embryonic development via the syncytial blastoderm, 0046668=regulation of retinal cell programmed cell death, 0007552=metamorphosis, 0016540=protein autoprocessing, 0007291=sperm individualization, 0035006=melanization defense response, 0008285=negative regulation of cell proliferation, 0012501=programmed cell death, 0051291=protein heterooligomerization, 0010506=regulation of autophagy, 0008258=head involution, 0006915=apoptotic process" "0043293=apoptosome, 0005737=cytoplasm, 0005739=mitochondrion" "CG8090, Dronc, Caspase-9-like, dronc, Drosophila Caspase-9 homologue, anon-EST:GressD6, anon-EST:GreesD6, Nedd 2-like caspase, anon-WO0118547.313, Nedd2-like caspase, DRONC, caspase-9, CG8091, Drosophila Nedd2-like caspase, Nc\Dronc, Dronc/Casp9, Nc" "IPR011029=Death-like domain, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR011600=Peptidase C14, caspase domain, IPR015917=Peptidase C14A, caspase precursor p45, core, IPR017350=Caspase, interleukin-1 beta convertase-type, IPR016129=Peptidase C14, ICE, catalytic subunit p20, active site, IPR029030=Caspase-like domain, IPR002138=Peptidase C14, caspase non-catalytic subunit p10" CG8091 16-Dec-15 2015_12 " adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage | third instar , embryonic stage | early " " egg chamber

, eye disc

, embryonic/larval midgut

,

ubiquitous , embryonic/larval salivary gland

, larval brain

" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,eye color defective,lethal - all die before end of pupal stage,temperature conditional,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,lethal - all die before end of embryonic stage,decreased cell death,some die during embryonic stage,female sterile,male sterile,partially,partially lethal - majority die,decreased cell number,lethal,recessive,maternal effect,neuroanatomy defective,short lived,cell death defective,developmental rate defective,melanotic necrosis,cell shape defective,viable,fertile,increased cell number,somatic clone,rescuable maternal effect,chemical resistant,size defective,lethal - all die before end of larval stage,some die during larval stage,male,wild-type" "eye,pigment cell,ommatidium,eye disc,temperature conditional,adult head,eye disc | third instar larval stage,spermatid,cystic bulge,waste bag,spermatogonial cyst,male germline cell,eye photoreceptor cell,eye disc | P-stage,embryonic/larval Malpighian tubule,retina,wing,dorsal multidendritic neuron ddaC,dendrite477,posterior,embryonic/larval fat body | wandering third instar larval stage,neuron,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage,postalar bristle,dendriteppk.1.9,retinal pigment cell,melanotic mass,embryonic/larval digestive system,somatic clone,eye-antennal disc,eye disc posterior to the morphogenetic furrow,embryonic/larval hemocyte,imaginal disc,embryonic/larval brain,ventral nerve cord primordium,rescuable maternal effect,ventral trunk epidermis primordium,dorsal ridge primordium,Bolwig organ,ventral nerve cord,ommatidial precursor cluster,embryonic/larval midgut,dendrite,imaginal disc epithelial cell,neuron & ventral nerve cord | ectopic,macrochaeta,sensory mother cell,eo neuron,thecogen cell,embryonic head,arista,egg chamber,male genitalia,neuroblast & larval abdominal segment 3 | late third instar larval stage,neuroblast & larval abdominal segment 4 | late third instar larval stage,neuroblast & larval abdominal segment 5 | late third instar larval stage,neuroblast & larval abdominal segment 6 | late third instar larval stage,neuroblast & larval abdominal segment 7 | late third instar larval stage,embryonic/larval salivary gland | P-stage,embryonic/larval neuromuscular junction,midline glial cell,maternal effect,presumptive embryonic/larval central nervous system,scolopidial neuron,peptidergic neuron,ectopic,cell autonomous,germline clone" FBgn0001308 Khc Kinesin heavy chain http://flybase.net/reports/FBgn0001308.html "FBgn0021886, FBgn0021889, FBgn0028613" protein_coding_gene "0005524=ATP binding, 0008574=ATP-dependent microtubule motor activity, plus-end-directed, 0008017=microtubule binding, 0003774=motor activity, 0003777=microtubule motor activity" "0030011=maintenance of cell polarity, 0008345=larval locomotory behavior, 0007411=axon guidance, 0046785=microtubule polymerization, 0051299=centrosome separation, 0047497=mitochondrion transport along microtubule, 0046843=dorsal appendage formation, 0048813=dendrite morphogenesis, 0006886=intracellular protein transport, 0007018=microtubule-based movement, 0007317=regulation of pole plasm oskar mRNA localization, 0019227=neuronal action potential propagation, 0001754=eye photoreceptor cell differentiation, 0048312=intracellular distribution of mitochondria, 0048311=mitochondrion distribution, 0045451=pole plasm oskar mRNA localization, 0007303=cytoplasmic transport, nurse cell to oocyte, 0048741=skeletal muscle fiber development, 0048812=neuron projection morphogenesis, 0007409=axonogenesis, 0040023=establishment of nucleus localization, 0008103=oocyte microtubule cytoskeleton polarization, 0007269=neurotransmitter secretion, 0051012=microtubule sliding, 0010970=microtubule-based transport, 0007315=pole plasm assembly, 0008088=axon cargo transport, 0016482=cytoplasmic transport, 0061572=actin filament bundle organization, 0007310=oocyte dorsal/ventral axis specification" "0005875=microtubule associated complex, 0035371=microtubule plus-end, 0005871=kinesin complex, 0005739=mitochondrion, 0005737=cytoplasm" "Kinesin-1 heavy chain, conventional kinesin, Kin, pgs, DmKHC, kinesin heavy chain, Kin-1 heavy chain, Dmkin, Kinesin-1, khc, DKH, KIF5B, kinesin 1, kinesin heavy chain I, kinesin-1 heavy chain, kinesin, Kinesin Heavy Chain, CG7765, DK, KHC, KIF 5A, l(2)k13219, kin, KIN, heavy chain of kinesin, l(2)W12, Kinesin, l(2R)W12, kinesin alpha subunit, kinesin I, partagas, l(2)k13314, kinesin alpha-chain, Kin-1, DmK, kinesin-1" "IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain" CG7765 16-Dec-15 2015_12 ENSDARG00000059818(LOC799274) WBGene00006840(unc-116) "ENSXETG00000011658(KIF5B),ENSXETG00000006230(KIF5A)" "ENSMUSG00000026764(Kif5c),ENSMUSG00000074657(Kif5a),ENSMUSG00000006740(Kif5b)" "ENSG00000170759(KIF5B),ENSG00000155980(KIF5A),ENSG00000168280(KIF5C)" adult stage head

", oogenesis stage && adult stage | female , larval stage | third instar , oogenesis stage | stage S8-10A , adult stage && oogenesis stage , embryonic stage " " germarium && oogonial cell

, female germline stem cell

, egg chamber | early & oogonial cell

ubiquitous , photoreceptor cell | apical

, oocyte | posterior

, stage S8 oocyte | anterior & dorsal && stage S9 oocyte | anterior & dorsal && stage S10A oocyte | anterior & dorsal , nurse cell

, oocyte

,

ubiquitous , follicle cell

" "paralytic,short lived,flightless,developmental rate defective,locomotor behavior defective,neurophysiology defective,lethal - all die before end of larval stage,heat sensitive,some die during larval stage,lethal,recessive,neuroanatomy defective,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,mitotic cell cycle defective,cytokinesis defective,wild-type,partially lethal - majority die,behavior defective,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,body color defective,majority die during third instar larval stage,majority die during pupal stage" "eye,somatic clone,ommatidium,embryonic/larval neuromuscular junction | larval stage,dendrite,dorsal appendage,germline clone,maternal effect,embryonic/larval brain,microtubule,oocyte,microtubule | germline clone,mitochondrion,oocyte & nucleus | germ-line clone,lateral transverse muscle,eye photoreceptor cell,rhabdomere,eye photoreceptor cell & endoplasmic reticulum | somatic clone,eye photoreceptor cell & multivesicular body | somatic clone,macrochaeta,microchaeta,scutellar bristle,adult cuticle & scutellar bristle | somatic clone,embryo,stage S9 oocyte & nucleus | germ-line clone,pole plasm,pole plasm | germline clone,nurse cell fusome,mitochondrial cloud | germline clone,follicle cell & mitochondrion | germ-line clone,germline cyst & mitochondrion | germ-line clone,microtubule & oocyte | oogenesis stage S9 | germ-line clone,class IV dendritic arborizing neuron,axon,neuromuscular junction,embryonic/larval nervous system,posterior fascicle & axon,axonw+),axonwvco),oocyte nucleus,chorion | germline clone,trichogen cell,mesothoracic tergum,peripheral nervous system,mitochondrionrepo.PL, repo,embryonic/larval glial cell,embryonic/larval wrapping glial cell of the eye disc | third instar larval stage,embryonic/larval peripheral nervous system | third instar larval stage" FBgn0004597 CycC Cyclin C http://flybase.net/reports/FBgn0004597.html protein_coding_gene "0005515=protein binding, 0019901=protein kinase binding, 0001104=RNA polymerase II transcription cofactor activity, 0016538=cyclin-dependent protein serine/threonine kinase regulator activity" "0000082=G1/S transition of mitotic cell cycle, 0045498=sex comb development, 0022416=chaeta development, 0036011=imaginal disc-derived leg segmentation, 0006367=transcription initiation from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0034472=snRNA 3'-end processing, 0007095=mitotic G2 DNA damage checkpoint, 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity" "0019908=nuclear cyclin-dependent protein kinase holoenzyme complex, 0016592=mediator complex" "cycC, CG1C_DROME, Cln3, dCycC, CYCC, SRB11, DmcycC, dTRAP33, CG7281, Cyc-C, cyclin C, cyclinC" "IPR013763=Cyclin-like, IPR006671=Cyclin, N-terminal, IPR015429=Cyclin C/H/T/L" CG7281 16-Dec-15 2015_12 ENSDARG00000009607(ccnc) YNL025C(SSN8) WBGene00000506(cic-1) ENSXETG00000026026(ccnc) ENSMUSG00000028252(Ccnc) ENSG00000112237(CCNC) " oogenesis stage && adult stage | female , embryonic stage -- adult stage , embryonic stage | early " ovary

"viable,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,visible,partially lethal - majority die" "sex comb,adult sense organ,leg,somatic clone - Minute background,sex comb tooth,somatic clone,prothoracic tarsal segment,mesothoracic bristle,mesothoracic tergum,trichogen cell" DRSC16619 K 0.588044502 0.203202611 -1.445716611 -0.000306956 1.677540876 1.166520197 FBgn0022734 l(1)3Ai lethal (1) 3Ai http://flybase.net/reports/FBgn0022734.html gene l[4] 16-Dec-15 2015_12 "lethal,recessive" polytene chromosome FBgn0011760 ctp cut up http://flybase.net/reports/FBgn0011760.html "FBgn0015619, FBgn0015650, FBgn0027256, FBgn0027271, FBgn0027293, FBgn0028265, FBgn0028273, FBgn0028298, FBgn0028309, FBgn0028322, FBgn0028337, FBgn0040189, FBgn0066852" protein_coding_gene "0042803=protein homodimerization activity, 0005515=protein binding, 0003777=microtubule motor activity, 0051959=dynein light intermediate chain binding, 0042623=ATPase activity, coupled, 0045505=dynein intermediate chain binding" "0022416=chaeta development, 0007291=sperm individualization, 0007476=imaginal disc-derived wing morphogenesis, 0000132=establishment of mitotic spindle orientation, 0022008=neurogenesis, 0007018=microtubule-based movement, 0035220=wing disc development, 0008407=chaeta morphogenesis, 0006914=autophagy, 0048477=oogenesis, 0035071=salivary gland cell autophagic cell death, 0007290=spermatid nucleus elongation, 0051017=actin filament bundle assembly, 0034454=microtubule anchoring at centrosome, 0007283=spermatogenesis" "0005814=centriole, 0030286=dynein complex, 0005868=cytoplasmic dynein complex, 0005856=cytoskeleton" "anon-WO03040301.128, Ctp, 8kd dynein light chain, dlc, l(1)G0153, l(1)G0445, l(1)G0432, Dynein light chain, l(1)G0338, Ddlc-1, Dlc, CG6998, l(1)G0244, Cytoplasmic dynein, lincRNA.S8635, dynein light chain LC8, cytoplasmic dynein, dynein light chain, ddlc1, l(1)G0204, l(1)G0207, Dynein light chain 1, dynein light-chain, dynein, cytoplasmic dynein light chain 1, dynein light-chain 1, Cdlc1, l(1)G0371, Ddlc1, Cytoplasmic dynein light chain 1, l(1)G0387, l(1)G0248, LC8, Cytoplasmic dynein 8kD light chain, dynein light chain 1, DLC8" "IPR019763=Dynein light chain, type 1/2, conserved site, IPR001372=Dynein light chain, type 1/2" CG6998 16-Dec-15 2015_12 ENSDARG00000058454(dynll1) YDR424C(DYN2) WBGene00001005(dlc-1) ENSXETG00000025899(DYNLL2) ENSMUSG00000020483(Dynll2) ENSG00000121083(DYNLL2) " embryonic stage | late , adult stage && oogenesis stage | stage >S10 , adult stage && oogenesis stage , embryonic stage -- adult stage , pupal stage , adult stage , embryonic stage " " chordotonal organ

, oocyte

, nurse cell

, embryonic central nervous system

, head

,

ubiquitous " " embryonic stage , oogenesis stage "

ubiquitous "viable,female sterile,visible,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive,recessive,partially lethal - majority live,male sterile,male fertile,poor,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,male semi-sterile,partially,wild-type,neuroanatomy defective,mitotic cell cycle defective,increased cell death" "scutum & macrochaeta,scutum & microchaeta,head & macrochaeta,macrochaeta,wing,wing vein,spermatid cyst,seminal vesicle,spermatozoon,spermatocyte fusome,wing & macrochaeta,ovariole,egg chamber,cystic bulge,actin filament bundle & nucleus,actin filament & spermatid,chaeta,salivary gland,lysosome | pupal stage,NMJ bouton,spermatid,nucleus & spermatid,scutum & macrochaeta & embryo,scutum & microchaeta & embryo,embryonic head & macrochaeta,leg & macrochaeta & embryo,sensory neuron,prothoracic femoral chordotonal organ & axon & pupa,longitudinal connective,commissure,prothoracic femoral chordotonal organ & axon,mesothoracic femoral chordotonal organ & axon,metathoracic femoral chordotonal organ & axon,astral microtubule,embryonic/larval neuroblast,astral microtubuleJC70),synaptonemal complex | somatic clone,somatic clone,ganglion mother cell,trichogen cell,tormogen cell,posterior compartment,wing disc" DRSC18758 IEK -2.163120436 -2.113667213 -1.500222659 -0.219841598 1.654270586 0.277847269 FBgn0037001 ND-39 NADH dehydrogenase (ubiquinone) 39 kDa subunit http://flybase.net/reports/FBgn0037001.html protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0050662=coenzyme binding, 0003954=NADH dehydrogenase activity" "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH ubiquinone oxidoreductase 39 kDa, FBpp0077859, NDUFA9, NADH:ubiquinone oxidoreductase 39 kDa subunit, CG6020, GM13757p, NADH dehydrogenase, NUEM, NADH-ubiquinone oxidoreductase 39 kDa subunit" "IPR001509=NAD-dependent epimerase/dehydratase, N-terminal domain, IPR016040=NAD(P)-binding domain" CG6020 16-Dec-15 2015_12 "ENSDARG00000070732,ENSDARG00000070723(ndufa9)" WBGene00021800(Y53G8AL.2) ENSXETG00000008484(Q5I0Q9_XENTR) ENSMUSG00000000399(Ndufa9) ENSG00000139180(NDUFA9) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0267548 CR45888 http://flybase.net/reports/FBgn0267548.html non_protein_coding_gene CR45888 16-Dec-15 2015_12 FBgn0016884 l(2)39DEi lethal (2) 39DEi http://flybase.net/reports/FBgn0016884.html gene D241 16-Dec-15 2015_12 lethal FBgn0267294 CR45730 http://flybase.net/reports/FBgn0267294.html non_protein_coding_gene CR45730 16-Dec-15 2015_12 FBgn0001033 Fs(3)Dam Female sterile (3) Damasa http://flybase.net/reports/FBgn0001033.html gene 0009792=embryo development ending in birth or egg hatching "Dam, Fs(3)Damasa, Fs(3)Sz7" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0264364 CG43816 http://flybase.net/reports/FBgn0264364.html protein_coding_gene CG43816 16-Dec-15 2015_12 FBgn0028994 saguaro saguaro http://flybase.net/reports/FBgn0028994.html gene 0048813=dendrite morphogenesis 16-Dec-15 2015_12 dendrite | dorsal | embryonic stage FBgn0266228 CR44923 http://flybase.net/reports/FBgn0266228.html non_protein_coding_gene lincRNA.672 CR44923 16-Dec-15 2015_12 FBgn0259941 ttd5 TRPL translocation defect 5 http://flybase.net/reports/FBgn0259941.html protein_coding_gene TRPL translocation defect 5 16-Dec-15 2015_12 FBgn0002999 omm ommatoreductum http://flybase.net/reports/FBgn0002999.html gene 16-Dec-15 2015_12 "viable,fertile,visible,recessive" "ommatidium,eye,adult head,head bristle,maxillary palpus,macrochaeta & adult thorax,wing" FBgn0260271 GSd466 http://flybase.net/reports/FBgn0260271.html gene 16-Dec-15 2015_12 lethal FBgn0024353 H217 H217 http://flybase.net/reports/FBgn0024353.html gene 16-Dec-15 2015_12 "viable,neuroanatomy defective,recessive" "optic lobe,medulla neuropil,medulla,proximal,lamina,distal,lobula plate" FBgn0036483 CG12316 http://flybase.net/reports/FBgn0036483.html protein_coding_gene "0043984=histone H4-K16 acetylation, 0045433=male courtship behavior, veined wing generated song production" 0072487=MSL complex IPR026711=Protein male-specific lethal-1 CG12316 16-Dec-15 2015_12 "song defective,partially lethal - majority die,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage DRSC09879 K 0.23269485 0.430565511 0.046557753 0.788846029 1.687490338 0.010109736 FBgn0024555 flfl falafel http://flybase.net/reports/FBgn0024555.html FBgn0038169 protein_coding_gene 0005515=protein binding "0006281=DNA repair, 0007391=dorsal closure, 0016601=Rac protein signal transduction, 0055059=asymmetric neuroblast division, 0008105=asymmetric protein localization, 0007405=neuroblast proliferation, 0006909=phagocytosis" "0030289=protein phosphatase 4 complex, 0000775=chromosome, centromeric region, 0043505=CENP-A containing nucleosome, 0005634=nucleus, 0005737=cytoplasm" "l(3)L4179, Flfl, Ppp4R3, PP4R3, CG9351, Falafel" "IPR016024=Armadillo-type fold, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006887=Domain of unknown function DUF625" CG9351 16-Dec-15 2015_12 ENSDARG00000042187(smek1) YNL201C(PSY2) WBGene00018285(smk-1) "ENSXETG00000015812(SMEK1),ENSXETG00000006072(BC076650.1)" "ENSMUSG00000041846(Smek1),ENSMUSG00000020463(Smek2)" "ENSG00000100796(SMEK1),ENSG00000138041(SMEK2)" "viable,fertile,lethal,recessive,female fertile,poor,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during third instar larval stage,decreased cell number,some die during larval stage,cell cycle defective" "wing,wing vein,mesothoracic tergum,neuroblast,cell" DRSC16474 IE -0.95830043 -2.070318391 -0.746483781 -3.562944432 0.019560106 0.750596516 FBgn0032475 Sfmbt Scm-related gene containing four mbt domains http://flybase.net/reports/FBgn0032475.html protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding, 0035064=methylated histone binding, 0003682=chromatin binding" "0006342=chromatin silencing, 0010629=negative regulation of gene expression, 0007446=imaginal disc growth, 0048477=oogenesis" "0031519=PcG protein complex, 0005634=nucleus" "dSFMBT, CG16975, SFMBT, dSfmbt" "IPR001660=Sterile alpha motif domain, IPR012313=Zinc finger, FCS-type, IPR004092=Mbt repeat, IPR013761=Sterile alpha motif/pointed domain" CG16975 16-Dec-15 2015_12 "ENSDARG00000060868(LOC568340),ENSDARG00000056079(l3mbtl2)" ENSXETG00000001291(mbtd1) "ENSMUSG00000059474(Mbtd1),ENSMUSG00000022394(L3mbtl2)" "ENSG00000011258(MBTD1),ENSG00000100395(L3MBTL2)" "tumorigenic,lethal - all die before end of larval stage,some die during third instar larval stage,lethal" "imaginal disc,female germline stem cell" FBgn0040080 pins partner of inscuteable http://flybase.net/reports/FBgn0040080.html "FBgn0020384, FBgn0039526" protein_coding_gene "0005515=protein binding, 0019904=protein domain specific binding, 0005092=GDP-dissociation inhibitor activity" "0055059=asymmetric neuroblast division, 0051294=establishment of spindle orientation, 0008356=asymmetric cell division, 0045185=maintenance of protein location, 0045175=basal protein localization, 0000132=establishment of mitotic spindle orientation, 0007405=neuroblast proliferation, 0045167=asymmetric protein localization involved in cell fate determination, 0008105=asymmetric protein localization, 0008277=regulation of G-protein coupled receptor protein signaling pathway, 0007400=neuroblast fate determination, 0040001=establishment of mitotic spindle localization" "0045179=apical cortex, 0045177=apical part of cell, 0005938=cell cortex" "Partner of Inscuteable, raps, rad, Rad, Rapsinoid, pins, Raps, CG5692, Partner of Inscutable, rapsyn, Pins, rapsynoid, PINS, partner of inscuteable, Rapsynoid" "IPR003109=GoLoco motif, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain, IPR019734=Tetratricopeptide repeat, IPR024804=G-protein-signalling modulator 1" CG5692 16-Dec-15 2015_12 "ENSDARG00000017311(LOC100332736),ENSDARG00000025027(gpsm2l)" WBGene00000092(ags-3) ENSXETG00000005230(GPSM2) "ENSMUSG00000027883(Gpsm2),ENSMUSG00000026930(Gpsm1)" "ENSG00000121957(GPSM2),ENSG00000160360(GPSM1)" embryonic stage " neuroblast

, mitotic domain 9

" "viable,visible,mitotic cell cycle defective,neuroanatomy defective,cell polarity defective,tumorigenic,cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "ganglion mother cell GMC4-2a,tormogen cell,mitotic domain 9 & spindle,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast,mitotic cell cycle & spindle,embryonic neuroblast & spindle,centrosome,larval brain & neuroblast,mitotic domain 9 & epithelial cell,spindle,aster,spindle & larval neuroblast,embryonic/larval neuroblast,spindle & external sensory organ precursor cell I,embryonic neuroblast,wing margin,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0024662 l(2)k06501 lethal (2) k06501 http://flybase.net/reports/FBgn0024662.html gene 65/1 16-Dec-15 2015_12 "lethal,recessive" imaginal disc FBgn0261430 CR42647 http://flybase.net/reports/FBgn0261430.html non_protein_coding_gene CR41487 16-Dec-15 2015_12 FBgn0022304 l(1)L48.3 lethal (1) L48.3 http://flybase.net/reports/FBgn0022304.html gene L48.3 16-Dec-15 2015_12 "lethal,recessive" FBgn0053286 CG33286 http://flybase.net/reports/FBgn0053286.html FBgn0037041 protein_coding_gene CG12982 IPR022110=Casc1 domain CG33286 16-Dec-15 2015_12 viable DRSC26119 K 0.267726939 0.083941492 0.491397888 0.335642288 2.721093434 1.641308951 FBgn0014919 anon-72ABc anon-72ABc http://flybase.net/reports/FBgn0014919.html gene 16-Dec-15 2015_12 FBgn0015317 U2af35 U2 small nuclear riboprotein auxiliary factor 35 http://flybase.net/reports/FBgn0015317.html FBgn0012029 gene "0000398=mRNA splicing, via spliceosome" 0005654=nucleoplasm "U2AF, U2AF-35kDa, U2AF[35]" 16-Dec-15 2015_12 FBgn0030102 CG12119 http://flybase.net/reports/FBgn0030102.html protein_coding_gene 0042826=histone deacetylase binding 0010629=negative regulation of gene expression "0005737=cytoplasm, 0005634=nucleus" lincRNA.971 IPR001214=SET domain CG12119 16-Dec-15 2015_12 "viable,fertile" FBgn0016977 spen split ends http://flybase.net/reports/FBgn0016977.html "FBgn0010537, FBgn0016056, FBgn0016624, FBgn0022059, FBgn0022080, FBgn0022115, FBgn0026182, FBgn0031230, FBgn0040065, FBgn0047291, FBtr0078121, FBpp0077780, FBtr0078122, FBpp0077781, FBtr0078123, FBpp0077782" protein_coding_gene "0000166=nucleotide binding, 0003676=nucleic acid binding" "0048106=establishment of thoracic bristle planar orientation, 0007400=neuroblast fate determination, 0007403=glial cell fate determination, 0008347=glial cell migration, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0007422=peripheral nervous system development, 0016055=Wnt signaling pathway, 0035321=maintenance of imaginal disc-derived wing hair orientation, 0007379=segment specification, 0035222=wing disc pattern formation, 0008586=imaginal disc-derived wing vein morphogenesis, 0007411=axon guidance, 0007173=epidermal growth factor receptor signaling pathway, 0050832=defense response to fungus, 0030177=positive regulation of Wnt signaling pathway" 0005634=nucleus "polycephalon, split-ends, yip1, EK2-9, E(E2F)2A, rno, yippee interacting protein 1, l(2)03350, poc, Split ends, 136/24, E(Sev-CycE)2A, l(2)k07612, EY2-7, spe, l(2)k08102, Spen, SPEN, l(2)k06805, CG18497, Splitends, BcDNA:GM01870, En(yan[ACT])2-7, E(Raf)2A, rhinoceros" "IPR012921=Spen paralogue and orthologue SPOC, C-terminal, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR016194=SPOC-like, C-terminal domain, IPR010912=Spen paralogue/orthologue C-terminal, metazoa, IPR000504=RNA recognition motif domain" CG18497 16-Dec-15 2015_12 WBGene00008549(din-1) ENSMUSG00000040761(Spen) ENSG00000065526(SPEN) " embryonic stage | 0-24 hr , embryonic stage , embryonic stage | 2-24 hr " " embryonic stage | stage 9-14 , embryonic stage , embryonic stage | stage >=3 , larval stage " " embryonic central nervous system

, embryonic epidermis

, organism

, eye disc

, ventral thoracic disc

, dorsal mesothoracic disc

" "lethal,recessive,immune response defective,wound healing defective,viable,fertile,visible,neuroanatomy defective,cell polarity defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "ommatidium,eye photoreceptor cell,hemocyte,plasmatocyte,crystal cell,macrochaeta,scutellar bristle,ectopic,dorsocentral bristle,tormogen cell,embryonic/larval central nervous system,neurite | pharate adult stage,midline glial cell,commissure,longitudinal connective,central nervous system,presumptive embryonic/larval peripheral nervous system,germline clone,presumptive embryonic/larval central nervous system,abdominal lateral pentascolopidial chordotonal organ lch5,intersegmental nerve,transverse nerve,abdominal segmental nerve,wing vein,somatic clone,crossvein,wing hair,wing margin bristle,microchaeta,head & cuticle | ectopic,embryonic thorax,embryonic thorax & cuticle,embryonic head,hypostomal sclerite,lch5 neuron,ventral midline,ventral nerve cord commissure,motor neuron,embryonic/larval somatic muscle,sclerite,embryonic mesothoracic segment & sclerite | ectopic,embryonic metathoracic segment & sclerite | ectopic,sclerite & embryonic abdominal segment | ectopic,mouth hooks,median tooth,dental sclerite,epipharyngeal sclerite,dorsal bridge,lateral process,embryonic epidermis,sclerite & embryonic head,chordotonal organ & axon | lateral,ventral thoracic disc,denticle belt,embryonic/first instar larval cuticle,eye,mesothoracic tergum,trichogen cell" FBgn0024250 brk brinker http://flybase.net/reports/FBgn0024250.html "FBtr0071048, FBpp0071007" protein_coding_gene "0001158=enhancer sequence-specific DNA binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0007399=nervous system development, 0010468=regulation of gene expression, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0010629=negative regulation of gene expression, 0007432=salivary gland boundary specification, 0007179=transforming growth factor beta receptor signaling pathway, 0030510=regulation of BMP signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0061328=posterior Malpighian tubule development, 0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0007472=wing disc morphogenesis, 0035212=cell competition in a multicellular organism" 0005634=nucleus "CG9653, ssg-1, Brk, Dm brk, small salivary glands-1, Brinker" IPR018586=Brinker DNA-binding domain CG9653 16-Dec-15 2015_12 " embryonic stage | stage 12 , embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage 9-11 , embryonic stage | stage 11 , embryonic stage | stage 14 , embryonic stage | early " " embryonic/larval midgut

, parasegment 5 &&of endoderm

, dorsal mesothoracic disc | restricted

, mesoderm | ventral

, dorsal mesothoracic disc | anterior

, ventral nerve cord primordium

, endoderm | restricted

, dorsal mesothoracic disc | posterior

, tracheal pit | vicinity of

, parasegment 5 &&of visceral mesoderm

, visceral mesoderm | restricted

, ectoderm | ventral

, ventral thoracic disc | restricted

, ectoderm | ventro-lateral

" larval stage | third instar " dorsal mesothoracic disc | posterior

, dorsal mesothoracic disc | anterior

" "partially lethal - majority die,lethal,recessive,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,cell autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,increased cell number,increased cell death,viable,partially,cell lethal,decreased cell number,mitotic cell cycle defective,cell non-autonomous,size defective,female semi-fertile,female fertile,partially lethal,some die during larval stage" "wing vein,ectopic,salivary gland,adult salivary gland primordium,denticle belt,commissure,longitudinal connective,embryonic/larval epidermis,embryonic head,wing,egg operculum,somatic clone,dorsal appendage,cell autonomous,hypostomal sclerite,crystal cell,neuroblast,ventral abdominal cluster,lateral,wing disc,dorsal hair,embryonic epidermis,ventral neurectoderm,dorsal,ventral,maternal effect,neuroblast NB2-4,neuroblast NB3-3,neuroblast NB4-2,neuroblast NB6-4,neuroblast NB7-3,neuroblast NB7-4,dorsal ectoderm,embryonic ventral epidermis,abdominal 1 ventral denticle belt,wing vein L4,wing vein L5,posterior crossvein,crossvein,posterior,wing blade,cardioblast,presumptive embryonic/larval peripheral nervous system,dorsal abdominal cluster,lateral abdominal cluster,embryonic/first instar larval cuticle,heat sensitive,imaginal disc,posterior compartment,cell non-autonomous,medial,eye,morphogenetic furrow,wing margin,micropyle | somatic clone,alula" FBgn0000320 eya eyes absent http://flybase.net/reports/FBgn0000320.html "FBgn0000623, FBgn0004612, FBgn0063692, FBtr0079334, FBpp0078963, FBtr0079335, FBpp0078964" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0016787=hydrolase activity, 0004721=phosphoprotein phosphatase activity, 0008134=transcription factor binding, 0030946=protein tyrosine phosphatase activity, metal-dependent" "0007419=ventral cord development, 0042675=compound eye cone cell differentiation, 0009996=negative regulation of cell fate specification, 0048749=compound eye development, 0006351=transcription, DNA-templated, 0045087=innate immune response, 0007280=pole cell migration, 0007435=salivary gland morphogenesis, 0007455=eye-antennal disc morphogenesis, 0008406=gonad development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042051=compound eye photoreceptor development, 0001744=optic lobe placode formation, 0007283=spermatogenesis, 0070285=pigment cell development, 0007526=larval somatic muscle development, 0010628=positive regulation of gene expression, 0007411=axon guidance, 0006470=protein dephosphorylation, 0009416=response to light stimulus, 0030707=ovarian follicle cell development, 0007498=mesoderm development, 0001746=Bolwig's organ morphogenesis, 0072499=photoreceptor cell axon guidance, 0008584=male gonad development" "0005634=nucleus, 0005737=cytoplasm" "eyes-absent, BcDNA:LD16029, 24582246, CLI, eyeless 2, Eyes-absent, clift, ey-2, Eya, Eyes absent, Eyes Absent, del1, CLIFT, eay, EY2-1, delayed gonad formation 1, CG9554, Clift, cli, EYA, Eyes-Absent, Eye absent, cli/eya, dEYA" "IPR028472=Eyes absent family, IPR006545=EYA domain, IPR023214=HAD-like domain" CG9554 16-Dec-15 2015_12 "ENSDARG00000014259(eya1),ENSDARG00000012397(eya4),ENSDARG00000036100(eya3)" WBGene00001377(eya-1) "ENSXETG00000015955(EYA1),ENSXETG00000003474(EYA2),ENSXETG00000000110(EYA4),ENSXETG00000012888(EYA3)" "ENSMUSG00000025932(Eya1),ENSMUSG00000010461(Eya4),ENSMUSG00000017897(Eya2),ENSMUSG00000028886(Eya3)" "ENSG00000104313(EYA1),ENSG00000112319(EYA4),ENSG00000064655(EYA2),ENSG00000158161(EYA3)" " larval stage , embryonic stage , adult stage " " eye-antennal disc

, adult head

, morphogenetic furrow | anterior

" " larval stage | third instar , larval stage | second instar , adult stage | male " " eye-antennal disc | gradient

, cyst cell

" "viable,fertile,visible,recessive,female sterile,cold sensitive,partially lethal - majority die,male sterile,female fertile,photoperiod response variant,auditory perception defective,eclosion rhythm defective,neuroanatomy defective,wild-type,lethal,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "gonad,eye,ommatidium,ocellus,germline cell,germarium,spermatid,spermatocyte,primary spermatocyte cyst,posterior vertical bristle,eye-antennal disc,lamina,photoreceptor cell,eye disc,somatic clone,photoreceptor cell & axon,lamina forming neuroblast,subretinal glial cell,presumptive embryonic salivary gland,cell autonomous,retina,denticle belt,cephalopharyngeal skeleton,embryonic/larval neuron,fat body/gonad primordium,somatic mesoderm,visceral mesoderm,embryonic/larval dorsal trunk,embryonic head,visual primordium,Bolwig organ,morphogenetic furrow,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,gonadal sheath proper primordium,male,lateral transverse muscle,dorsal oblique muscle,ventral oblique muscle,ventral acute muscle,embryonic/larval somatic muscle,border follicle cell,supernumerary,polar follicle cell,ectopic,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & embryonic abdominal segment 9 | lateral,antenno-maxillary complex,embryonic/larval labral segment sense organ,hypophysis,embryonic brain,cell non-autonomous,adult head & adult cuticle | ectopic | somatic clone,orbital bristle,lateral longitudinal muscle 1,precursor,head capsule,scutellar bristle,macrochaeta,wing vein L3,wing,antennal segment & eye | ectopicdpp.blk1,leg & ommatidium | ectopicdpp.blk1,wing & ommatidium | ectopicdpp.blk1,antennal segment,leg,interfollicle cell,egg chamber & basement membrane | apicalupd.PU,antenna,metathoracic leg,wing hinge,head,arista,adult head,antennal disc,embryonic/larval brain | third instar larval stage,dorsal" FBgn0065580 l(2)SH0942 lethal (2) SH0942 http://flybase.net/reports/FBgn0065580.html gene l(2)SH2 0942 16-Dec-15 2015_12 "lethal,recessive" FBgn0053425 5SrRNA:CR33425 5SrRNA:CR33425 http://flybase.net/reports/FBgn0053425.html rRNA_gene 0003735=structural constituent of ribosome 0006412=translation 0022626=cytosolic ribosome CR33425 CR33425 16-Dec-15 2015_12 FBgn0010620 CG10939 http://flybase.net/reports/FBgn0010620.html FBgn0034209 protein_coding_gene "0042048=olfactory behavior, 0030036=actin cytoskeleton organization, 0007476=imaginal disc-derived wing morphogenesis" 0045177=apical part of cell "Sip1, CG10939, SRY interacting protein 1, l(2)06373" IPR001478=PDZ domain CG10939 16-Dec-15 2015_12 "ENSDARG00000000068(slc9a3r1),ENSDARG00000057669" "ENSXETG00000006840(slc9a3r2),ENSXETG00000015931(SLC9A3R2)" "ENSMUSG00000020733(Slc9a3r1),ENSMUSG00000002504(Slc9a3r2)" "viable,smell perception defective,lethal,recessive,visible" "follicle cell,somatic clone,filamentous actin | somatic clone,wing vein L3,wing vein,ectopic" FBgn0013254 E(var)3-8 E(var)3-8 http://flybase.net/reports/FBgn0013254.html gene E-var(3)8 16-Dec-15 2015_12 "enhancer of variegation,dominant" FBgn0061019 l(3)S025507 lethal (3) S025507 http://flybase.net/reports/FBgn0061019.html gene 0255/07 16-Dec-15 2015_12 "partially lethal - majority die,recessive" FBgn0031202 CG13237 http://flybase.net/reports/FBgn0031202.html protein_coding_gene 16-Dec-15 2015_12 FBgn0266741 CR45214 http://flybase.net/reports/FBgn0266741.html non_protein_coding_gene CR45214 16-Dec-15 2015_12 FBgn0265554 12.19 http://flybase.net/reports/FBgn0265554.html gene 16-Dec-15 2015_12 learning defective FBgn0002654 mat(2)cell-C maternal effect cellularisation defect C http://flybase.net/reports/FBgn0002654.html gene 0007349=cellularization "mat(2)cellPK42, cell-PK42" 16-Dec-15 2015_12 "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0035479 CG14983 http://flybase.net/reports/FBgn0035479.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0016567=protein ubiquitination 0005634=nucleus "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG14983 16-Dec-15 2015_12 viable FBgn0000028 acj6 abnormal chemosensory jump 6 http://flybase.net/reports/FBgn0000028.html "FBgn0004418, FBgn0030633" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0003714=transcription corepressor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0070983=dendrite guidance, 0007411=axon guidance, 0008039=synaptic target recognition, 0048813=dendrite morphogenesis, 0007636=chemosensory jump behavior" 0005634=nucleus "Twin of I-POU, Abnormal chemosensory jump 6, tI-POU, Acj6, altered chemosensory jump 6, Ipou, I-POU, ACJ6, CG9151, Abnormal chemosensory jumb" "IPR000327=POU-specific domain, IPR010982=Lambda repressor-like, DNA-binding domain, IPR001356=Homeobox domain, IPR013847=POU domain, IPR015584=POU domain-containing protein, class 4-related, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG9151 16-Dec-15 2015_12 "ENSDARG00000044375(zgc:158291),ENSDARG00000069737(pou4f2),ENSDARG00000005559,ENSDARG00000006206(pou4f3)" WBGene00006818(unc-86) "ENSXETG00000018386(),ENSXETG00000017814(POU4F1)" "ENSMUSG00000048349(Pou4f1),ENSMUSG00000024497(Pou4f3)" "ENSG00000151615(POU4F2),ENSG00000091010(POU4F3)" embryonic stage " ventral nerve cord

, EL neuron

, supraesophageal ganglion

, RP1 neuron

, aCC neuron

, pCC neuron

, embryonic central nervous system

, U neuron

" "viable,fertile,lethal,recessive,smell perception defective,neurophysiology defective,behavior defective,chemosensitive behavior defective,locomotor behavior defective,chemical sensitive,neuroanatomy defective,somatic clone,cell autonomous,male,cell non-autonomous" "adult olfactory receptor neuron Or42a,adult olfactory receptor neuron Or71a,lamina plexus,maxillary palp sense organ,antennal sense organ,lamina monopolar neuron L1,lamina monopolar neuron L3,monopolar laminar cell L1 & synapse,monopolar laminar cell L3 & synapse,antennal glomerulus & neuron | somatic clone,antennal glomerulus VA3 & neuron | somatic clone,antennal glomerulus VM2 & neuron | somatic clone,antennal glomerulus DM6 & neuron | somatic clone,antennal glomerulus DL1 & neuron | somatic clone,antennal glomerulus D & neuron | somatic clone,antennal glomerulus VA1 & neuron | somatic clone,olfactory sensory organ & neuron & dendrite | somatic clone,maxillary palp sensillum basiconicum,antennal lobe glomerulus,male,axon & olfactory neuron & antennal glomerulus DA4 | male | cell autonomous,axon & olfactory neuron & antennal glomerulus DM3 | male | cell autonomous,axon & olfactory neuron & antennal glomerulus VA6 | male | cell autonomous,axon & olfactory neuron & antennal glomerulus VC2 | male | cell non-autonomous,axon & olfactory neuron & antennal glomerulus V | male | cell non-autonomous,axon & olfactory neuron | male | ectopic,axon & olfactory neuron & antennal glomerulus DA4 | somatic clone | cell autonomous,axon & olfactory neuron & antennal glomerulus DM3 | somatic clone | cell autonomous,axon & olfactory neuron & antennal glomerulus VA6 | somatic clone | cell autonomous,axon & olfactory neuron & antennal glomerulus VC2 | somatic clone | cell non-autonomous,axon & olfactory neuron & antennal glomerulus V | somatic clone | cell non-autonomous,axon & olfactory neuron | somatic clone | ectopic,olfactory neuron & maxillary palp sense organ,adult antennal lobe projection neuron DL1 adPN,somatic clone,adult antennal lobe projection neuron D adPN,adult antennal lobe projection neuron VA3 adPN,adult antennal lobe projection neuron VM2 adPN,adult antennal lobe projection neuron DM6 adPN,adult antennal lobe projection neuron VA1v adPN,antennal lobe glomerulus DL1,antennal lobe glomerulus D,antennal lobe glomerulus VA3,antennal lobe glomerulus VM2,antennal lobe glomerulus DM6,antennal lobe glomerulus VA1v,anterior fascicle & motor neuron-537.4,abdominal ventral longitudinal muscle 3 & neuromuscular junction-537.4,abdominal ventral longitudinal muscle 4 & neuromuscular junction-537.4,abdominal ventral longitudinal muscle 1 & neuromuscular junction-537.4,abdominal ventral longitudinal muscle 2 & neuromuscular junction-537.4,neuromuscular junction | ectopic-537.4,bouton,ectopic,motor neuron | embryonic stage,antennal glomerulus & neuronGH146,olfactory sensory organ & neuron & dendriteGH146" FBgn0013725 phyl phyllopod http://flybase.net/reports/FBgn0013725.html protein_coding_gene "0060090=binding, bridging, 0005515=protein binding, 0043621=protein self-association, 0030674=protein binding, bridging" "0016360=sensory organ precursor cell fate determination, 0007462=R1/R6 cell fate commitment, 0045467=R7 cell development, 0010498=proteasomal protein catabolic process, 0007465=R7 cell fate commitment, 0008052=sensory organ boundary specification, 0008593=regulation of Notch signaling pathway, 0046331=lateral inhibition, 0001751=compound eye photoreceptor cell differentiation, 0007422=peripheral nervous system development, 0007265=Ras protein signal transduction, 0030111=regulation of Wnt signaling pathway" "0005634=nucleus, 0000151=ubiquitin ligase complex" "Phyllopod, SR2-3, D(DmcycE[JP])2.2, phy1, Phyl, Su(Raf)2C, PHYL, CG10108" CG10108 16-Dec-15 2015_12 larval stage " morphogenetic furrow

, eye-antennal disc

" "lethal,recessive,wild-type,visible,dominant,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,partially,somatic clone,viable" "eye,photoreceptor cell R7,cone cell,precursor,supernumerary,photoreceptor cell R1,photoreceptor cell R6,ommatidium,macrochaeta & scutum,microchaeta & scutum,interommatidial bristle,chordotonal organ & neuron,multidendritic neuron,external sensory organ & neuron,chaeta,somatic clone,eo neuron,thecogen cell,primary pigment cell,mesothoracic tergum & microchaeta,adult abdominal segment 3 & microchaeta,adult abdominal segment 4 & microchaeta,mesothoracic tergum & trichogen cell | supernumerary,mesothoracic tergum & tormogen cell | supernumerary,mesothoracic tergum & chaeta,adult abdominal segment 3 & trichogen cell | supernumerary,adult abdominal segment 3 & tormogen cell | supernumerary,adult abdominal segment 3 & chaeta,adult abdominal segment 4 & trichogen cell | supernumerary,adult abdominal segment 4 & tormogen cell | supernumerary,adult abdominal segment 4 & chaeta,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 4,socket,cephalopharyngeal skeleton,germline clone,filzkorper,A1-7 dorsal transverse muscle 1,A1-7 lateral transverse muscle 4,mesothoracic tergum & microchaeta | ectopicEq1,external sensory organ,ectopic,mesothoracic tergum,scutellar bristle,wing vein L3 & chaeta | ectopicdpp.blk1,sensory neuron,microchaeta,neuron,trichogen cell,tormogen cell" FBgn0005395 gate gate http://flybase.net/reports/FBgn0005395.html "FBgn0001093, FBgn0003154" gene 0008062=eclosion rhythm "psi 2, psi-2, phase-angle-2, gat, psi2, phase-angle2" 16-Dec-15 2015_12 "eclosion rhythm defective,semidominant,locomotor rhythm defective,courtship behavior defective,male,locomotor behavior defective,recessive" FBgn0014052 Su(tor)2-3 Su(tor)2-3 http://flybase.net/reports/FBgn0014052.html gene 16-Dec-15 2015_12 "lethal,maternal effect,recessive" FBgn0051146 Nlg1 Neuroligin 1 http://flybase.net/reports/FBgn0051146.html "FBgn0037510, FBgn0037511, FBgn0062140" protein_coding_gene "0004872=receptor activity, 0042043=neurexin family protein binding, 0052689=carboxylic ester hydrolase activity" "0007528=neuromuscular junction development, 0051124=synaptic growth at neuromuscular junction, 0007416=synapse assembly" "0005887=integral component of plasma membrane, 0009986=cell surface, 0031594=neuromuscular junction" "nlg1, neuroligin, neuroligin 1, anon-WO0118547.256, CG31146, CG14596, DNlg1, CG12148, dnlg1" "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR019826=Carboxylesterase type B, active site, IPR002018=Carboxylesterase, type B" CG31146 16-Dec-15 2015_12 WBGene00013540(Y75B8A.3) "neuroanatomy defective,neurophysiology defective,viable,fertile" "synapse,bouton,synapseED5223),synapseBG487,neuromuscular junction,neuromuscular junction | larval stage,subsynaptic reticulum,NMJ bouton,NMJ bouton | third instar larval stage,neuromuscular junctionMef2.PR,neuromuscular junction | larval stageMef2.PR,presynaptic cytoskeletal matrix assembled at active zones | third instar larval stage" DRSC12485 I -0.640843946 -2.037697114 -0.009935752 -0.299083309 -0.155071751 -0.854213983 FBgn0046214 vig2 vig2 http://flybase.net/reports/FBgn0046214.html "FBgn0039279, FBgn0062116" protein_coding_gene "0070828=heterochromatin organization, 0031935=regulation of chromatin silencing, 0051567=histone H3-K9 methylation" "0005700=polytene chromosome, 0005703=polytene chromosome puff, 0005634=nucleus, 0005737=cytoplasm, 0005701=polytene chromosome chromocenter" "CG11844, vig-2, BcDNA:SD06613, anon-WO0118547.290" IPR006861=Hyaluronan/mRNA-binding protein CG11844 16-Dec-15 2015_12 "ENSDARG00000003474,ENSDARG00000069400,ENSDARG00000025174(zgc:103482)" WBGene00006924(vig-1) "ENSXETG00000012394(pairbp1),ENSXETG00000014841(habp4)" "ENSMUSG00000036371(Serbp1),ENSMUSG00000021476(Habp4)" "ENSG00000142864(SERBP1),ENSG00000130956(HABP4)" "viable,fertile,suppressor of variegation,dominant,enhancer of variegation,lethal - all die before end of P-stage,some die during P-stage" DRSC30012 IK 3.055946703 -0.003760885 -0.655191502 0.135107198 0.319817587 2.89813172 FBgn0027337 l(1)2Cg lethal (1) 2Cg http://flybase.net/reports/FBgn0027337.html gene unnamed 16-Dec-15 2015_12 "lethal,recessive" FBgn0060405 l(3)S130901 lethal (3) S130901 http://flybase.net/reports/FBgn0060405.html gene 1309/01 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0032535 Ance-2 Ance-2 http://flybase.net/reports/FBgn0032535.html FBgn0051844 protein_coding_gene "0008241=peptidyl-dipeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis 0016020=membrane "ance-2, CG31844, CG16869" "IPR001548=Peptidase M2, peptidyl-dipeptidase A" CG16869 16-Dec-15 2015_12 viable FBgn0260444 Not10 http://flybase.net/reports/FBgn0260444.html FBgn0028495 protein_coding_gene "0017148=negative regulation of translation, 0006402=mRNA catabolic process" 0030014=CCR4-NOT complex "CG18616, NOT10, dNot10" IPR011990=Tetratricopeptide-like helical domain CG18616 16-Dec-15 2015_12 "viable,fertile" DRSC14129 K -0.52639716 -0.535237536 -0.752034271 1.03631914 0.238141803 1.746643978 FBgn0261437 CSN8 COP9 signalosome subunit 8 http://flybase.net/reports/FBgn0261437.html "FBgn0028835, FBgn0005776, FBgn0032027, FBgn0053297, FBgn0065343" protein_coding_gene 0019784=NEDD8-specific protease activity "0007476=imaginal disc-derived wing morphogenesis, 0042742=defense response to bacterium, 0010387=COP9 signalosome assembly, 0050821=protein stabilization, 0051726=regulation of cell cycle, 0007095=mitotic G2 DNA damage checkpoint, 0048477=oogenesis, 0010388=cullin deneddylation, 0001745=compound eye morphogenesis" 0008180=COP9 signalosome "CG13383, l(2)SH2 1829, CG33297, Cop9 signalosome subunit 8, CSN8, CG42522, Drosophila COP9 signalosome homolog 8, csn8, CH8, Dch8, l(2)SH1829, lethal (2) SH1829, COP9 complex homolog subunit 8, Csn8" CG42522 16-Dec-15 2015_12 ENSDARG00000024846(cops8) ENSXETG00000025427(cops8) ENSMUSG00000034432(Cops8) "ENSG00000198612(COPS8),ENSG00000214552" "lethal,recessive,immune response defective,developmental rate defective,small body,melanotic mass phenotype,visible,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage" "melanotic mass,ovary,germline clone,eye,somatic clone,wing,wing vein,ectopic,posterior crossvein,scutellum,mesothoracic tergum,chaeta & mesothoracic tergum | somatic clone" DRSC02257 K 0.040838745 -0.053864819 -0.440448528 0.026810359 1.952280601 1.215695573 FBgn0014387 sov small ovary http://flybase.net/reports/FBgn0014387.html FBgn0000898 gene "female sterile(1)M105, fs(1)M105" 16-Dec-15 2015_12 "female sterile,male fertile,lethal,recessive" "germline cyst,ovariole,ovary,egg chamber" FBgn0004227 nonA no on or off transient A http://flybase.net/reports/FBgn0004227.html "FBgn0000188, FBgn0002957" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0008187=poly-pyrimidine tract binding" "0042331=phototaxis, 0007601=visual perception, 0007632=visual behavior, 0045433=male courtship behavior, veined wing generated song production, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005634=nucleus" "no-on-transient-A, NonA, Bj6-1, p54[nrb], non-on-transient-A, no-on transient A, x14, diss, CG4211, non-A, dissonance, no-on-transient A, Positive spike II group, Bj6-monoclonal-antibody, no on or off transient-A, NONA, nonA/diss, Bj6, opm2" "IPR012975=NOPS, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG4211 16-Dec-15 2015_12 "ENSDARG00000020482(nono),ENSDARG00000011564(sfpq),ENSDARG00000006621(pspc1)" WBGene00017778(psf-1) "ENSXETG00000009682(SFPQ),ENSXETG00000020868(nono)" "ENSMUSG00000028820(Sfpq),ENSMUSG00000021938(Pspc1),ENSMUSG00000031311(Nono)" "ENSG00000116560(SFPQ),ENSG00000121390(PSPC1),ENSG00000147140(NONO)" embryonic stage

ubiquitous " embryonic stage | cellular blastoderm , embryonic stage , adult stage , adult stage && oogenesis stage , larval stage , larval stage | third instar , pupal stage " "

ubiquitous , oocyte | ubiquitous

, follicle cell

, oocyte

, larval salivary gland

, nurse cell

" "viable,fertile,optomotor response defective,courtship behavior defective,male,recessive,song defective,visual behavior defective,behavior defective,neurophysiology defective,wild-type,lethal,partially,flight defective,locomotor behavior defective" DRSC20357 EK 0.806077155 0.297512295 0.532311372 1.915161797 -1.733480479 -1.802325187 FBgn0003444 smo smoothened http://flybase.net/reports/FBgn0003444.html protein_coding_gene "0005515=protein binding, 0004888=transmembrane signaling receptor activity, 0004930=G-protein coupled receptor activity" "0030707=ovarian follicle cell development, 0001746=Bolwig's organ morphogenesis, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0007350=blastoderm segmentation, 0048592=eye morphogenesis, 0007165=signal transduction, 0007346=regulation of mitotic cell cycle, 0045746=negative regulation of Notch signaling pathway, 0042981=regulation of apoptotic process, 0002385=mucosal immune response, 0007224=smoothened signaling pathway, 0035019=somatic stem cell maintenance, 0090004=positive regulation of establishment of protein localization to plasma membrane, 0048100=wing disc anterior/posterior pattern formation, 0007193=adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, 0007455=eye-antennal disc morphogenesis, 0048099=anterior/posterior lineage restriction, imaginal disc" "0005768=endosome, 0005887=integral component of plasma membrane, 0043025=neuronal cell body, 0016021=integral component of membrane, 0030425=dendrite, 0005886=plasma membrane, 0030424=axon, 0005929=cilium" "CG11561, SMO, dSmo, Smoothene, Smo, smooth, Smoothened" "IPR026544=Smoothened, IPR017981=GPCR, family 2-like, IPR020067=Frizzled domain, IPR015526=Frizzled/secreted frizzled-related protein, IPR000539=Frizzled protein" CG11561 16-Dec-15 2015_12 ENSDARG00000002952(smo) ENSXETG00000014939(SMO) ENSMUSG00000001761(Smo) ENSG00000128602(SMO) embryonic stage && larval stage && adult stage "visible,lethal,wild-type,recessive,neuroanatomy defective,size defective,somatic clone,segment polarity phenotype,cold sensitive,mitotic cell cycle defective,cell autonomous,cell non-autonomous,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" "crossvein,ectopic,wing vein,wing blade,anterior,wing,embryonic/larval tracheal system,embryonic/larval dorsal branch,wing vein L3,wing vein L4,presumptive embryonic/larval peripheral nervous system,longitudinal connective,ventral nerve cord commissure,heart primordium,Bolwig organ,germline clone,embryonic/first instar larval cuticle,denticle,supernumerary,germline cell,cold sensitive,morphogenetic furrow,photoreceptor cell,wing disc,anterior/posterior compartment boundary,follicle stem cell,somatic clone,embryonic epidermis,medial ocellus,ocellus,eye disc,anterior compartment,denticle belt,1st posterior cell,tergite,epiproct,anal plate,female gonopod,abdominal tergite 8,genital arch,clasper,hypandrial bristle,posterior compartment,lamina & neuron | precursor | somatic clone,photoreceptor cell R8,precursor,photoreceptor cell & neuron,ommatidial precursor cluster,adult abdomen & cuticle | anterior compartment,adult abdomen & microchaeta | anterior compartment,eye,adult cuticle,scutellum,microchaeta,photoreceptor cell R8 & eye disc | somatic clone,double row,wing margin,adult head,adult thorax,leg,cell non-autonomous,morphogenetic furrow & nucleus | somatic clone,cell autonomous,third segment of antenna,maxillary palpus,maxillary palp olfactory receptor neuron,wing pouch,head capsule,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal segment 10,abdominal segment 11,ovariole,germarium region 3,egg chamber,interfollicle cell,proximal,costal cell,submarginal cell,wing vein L1,wing cell,imaginal disc anterior compartment,wing vein L2,wing disc | third instar larval stage,campaniform sensillum of anterior crossvein" FBgn0002781 mod(mdg4) modifier of mdg4 http://flybase.net/reports/FBgn0002781.html "FBgn0010160, FBgn0010321, FBgn0010822, FBgn0011326, FBgn0024544, FBgn0038882, FBgn0038883, FBgn0038884, FBgn0038885, FBgn0040578, FBgn0040579, FBgn0040580, FBgn0046992, FBgn0052491, FBgn0063265" protein_coding_gene "0008195=phosphatidate phosphatase activity, 0005515=protein binding, 0042803=protein homodimerization activity, 0003677=DNA binding, 0031208=POZ domain binding, 0003682=chromatin binding" "0001672=regulation of chromatin assembly or disassembly, 0006915=apoptotic process, 0010032=meiotic chromosome condensation, 0008354=germ cell migration, 0048477=oogenesis, 0006325=chromatin organization, 0007141=male meiosis I, 0007060=male meiosis chromosome segregation" "0000794=condensed nuclear chromosome, 0005634=nucleus, 0005704=polytene chromosome band, 0000785=chromatin, 0005730=nucleolus, 0005886=plasma membrane, 0005700=polytene chromosome" "mdg4, mod(mdg4)67.2, Modifier of mdg 4 67.2, Mod(mdg4)67.2, CG15501, MOD(MDG4), CG15500, l(3)L3101, E-var(3)3, Mod(mdg 4)67.2, Mod[mdg4], BcDNA:SD03001, Modifier67.2, modMDG4, Doom, Modifier of mdg4 67.2, CG32491, modifier of midget4, mod, mnn, Mod(mdg)4, MOD(MDG4)56.3, bpd, CG8076, mod(mdg4 isoform N), mod(mdg4)-67.2, Mod2.2, l(3)j2B7, CG18151, mod[mdg4], mod(mdg4, branch point disrupted, modifier mdg4, Mod67.2, Modifier of mdg4, E-var(3)1, Enhancer of variegation 93D, mod2.2, modifier of mdg4 in meiosis, Modifier of (mdg4) 67.2, E-(var)3-93D, E(var)3-93D, MOD2.2, CG7836, CG7859, BcDNA:GH07769, mnm, pf-2, Mod(mdg4), l(3)03852, mod(mdg-4), CG15802, E(var)93D, Mod(mdg 4), E(var)129, Mod(mdg4)-67.2, doom, Mod(mdg4)2.2, mod (mdg4), mod(gypsy)" "IPR000210=BTB/POZ domain, IPR007588=Zinc finger, FLYWCH-type, IPR011333=POZ domain" CG32491 16-Dec-15 2015_12 adult stage organism

"viable,lethal,recessive,polyphasic,female sterile,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,dominant,partially lethal - majority die,cold sensitive,heat sensitive,suppressor of variegation,non-suppressor of variegation,non-enhancer of variegation,meiotic cell cycle defective,male,neuroanatomy defective,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,female fertile,male sterile" "terminal filament,ovary,ovariole,neuromuscular junction | larval stage,neuromuscular junction & abdominal ventral longitudinal muscle 1,neuromuscular junction & abdominal ventral longitudinal muscle 2,neuromuscular junction & abdominal dorsal acute muscle 1,neuromuscular junction & abdominal dorsal acute muscle 2,neuromuscular junction & abdominal dorsal acute muscle 3,neuromuscular junction & abdominal lateral longitudinal muscle 1,neuromuscular junction & abdominal dorsal oblique muscle 4,neuromuscular junction & abdominal dorsal oblique muscle 5,neuromuscular junction & abdominal ventral acute muscle 3,abdominal segment motor neuron,eye,wing,motor neuron | third instar larval stage,wing vein L2,embryo,abdominal ventral longitudinal muscle 3 & neuromuscular junction,neuromuscular junction | ectopic,neuromuscular junction & postsynaptic membrane & larva,meiosis I & nuclear chromosome,G2 phase & nuclear chromosome" FBgn0005677 dac dachshund http://flybase.net/reports/FBgn0005677.html protein_coding_gene 0005515=protein binding "0035215=genital disc development, 0007411=axon guidance, 0007479=leg disc proximal/distal pattern formation, 0035211=spermathecum morphogenesis, 0035263=genital disc sexually dimorphic development, 0006351=transcription, DNA-templated, 0030182=neuron differentiation, 0042051=compound eye photoreceptor development, 0010629=negative regulation of gene expression, 0043704=photoreceptor cell fate specification, 0016319=mushroom body development, 0007483=genital disc morphogenesis, 0048098=antennal joint development, 0048749=compound eye development" 0005634=nucleus "l(2)36Ae, Dac, Dach, dacshund, Dachshund, dach, spn, DACHSHUND, dachsund, spinosus, BG:DS02780.3, DAC, Dm-DAC, CG4952, daschund, l(2)rK364, Dac2-3" "IPR009061=Putative DNA-binding domain, IPR003380=Transforming protein Ski" CG4952 16-Dec-15 2015_12 "ENSDARG00000069440(zgc:158869),ENSDARG00000003142(dachc),ENSDARG00000010132(dacha),ENSDARG00000034785(dachb)" "ENSMUSG00000055639(Dach1),ENSMUSG00000025592(Dach2)" "ENSG00000165659(DACH1),ENSG00000126733(DACH2)" " larval stage , embryonic stage | stage 11 , embryonic stage | stage 9-11 , embryonic stage | stage >=9 , larval stage && pupal stage && adult stage , embryonic stage , adult stage | male " " dorsal metathoracic disc

, procephalic neurogenic region && embryonic antennal segment | dorsal & restricted

, photoreceptor cell R7

, protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | dorsal & restricted

, photoreceptor cell R6

, mushroom body

, ventral thoracic disc

, embryonic central nervous system | restricted

, cone cell

, organism

, tritocerebral neuroblast | subset

, eye-antennal disc

, procephalic neurogenic region && embryonic protocerebrum | restricted

, optic lobe

, photoreceptor cell R1

" "lethal,recessive,visible,dominant,somatic clone,neuroanatomy defective" "eye,ommatidium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,leg,eye-antennal disc,morphogenetic furrow,mushroom body gamma-lobe,adult mushroom body,prothoracic leg & sex comb,sex comb,ectopic,tarsal segment 2,metatarsus,mushroom body alpha-lobe,mushroom body beta-lobe,adult mushroom body beta'-lobe,calyx of adult mushroom body,ellipsoid body,mushroom body spur,prothoracic tibia,prothoracic femur,prothoracic metatarsus,prothoracic tarsal segment 2,prothoracic tarsal segment 3,mesothoracic tibia,mesothoracic femur,mesothoracic metatarsus,mesothoracic tarsal segment 2,mesothoracic tarsal segment 3,metathoracic tibia,metathoracic femur,metathoracic tarsal segment 2,metathoracic tarsal segment 3,ventral thoracic disc,lamina tangential neuron,metathoracic metatarsus,fifth segment of antenna,arista,somatic clone,femur,tibia,tarsal segment,joint,spermathecal duct,clasper,clasper long bristle,clasper tooth,adult mushroom body alpha'-lobe,adult head,wing,bract,antenna,rhabdomeredpp.blk1,interommatidial bristle,anterior/posterior compartment boundary,wing disc,eye | ectopic & adult headGMR.long,eye | ectopic & female genitalia7B" FBgn0004449 Ten-m Tenascin major http://flybase.net/reports/FBgn0004449.html "FBgn0010864, FBgn0011500, FBgn0011513, FBgn0011526, FBgn0011680, FBgn0024864, FBgn0037160, FBgn0047332" protein_coding_gene "0042802=identical protein binding, 0031005=filamin binding" "0001745=compound eye morphogenesis, 0042051=compound eye photoreceptor development, 0008360=regulation of cell shape, 0016200=synaptic target attraction, 0048058=compound eye corneal lens development, 0045467=R7 cell development, 0008045=motor neuron axon guidance, 0007155=cell adhesion, 0051124=synaptic growth at neuromuscular junction, 0022416=chaeta development" "0045211=postsynaptic membrane, 0005887=integral component of plasma membrane, 0005886=plasma membrane, 0031594=neuromuscular junction, 0005578=proteinaceous extracellular matrix" "ten-m/odz, ten[m], l(3)rP126, ten-m, odz, tenascin major, Ten-mc, 2017, l(3)00844, ten(m), l(3)05301, CG11452, CT16449, unnamed, tenascin-like molecule major, CG5723, Tenascin-major, l(3)rL201, odd-Oz, Odz, Teneurin, Ten79E, tenascin-major, 5301, odz/ten-m, odd Oz, Ten[m], l(3)rJ307, odd(Oz), BcDNA:AT25108, l(3)05309" "IPR000742=EGF-like domain, IPR006530=YD repeat, IPR011042=Six-bladed beta-propeller, TolB-like, IPR013032=EGF-like, conserved site, IPR031325=RHS repeat, IPR008969=Carboxypeptidase-like, regulatory domain, IPR028916=Tox-GHH domain" CG5723 16-Dec-15 2015_12 "ENSDARG00000005479(odz3),ENSDARG00000034264(odz4),ENSDARG00000007627,ENSDARG00000037122(LOC563197),ENSDARG00000011171,ENSDARG00000003403(LOC563094)" WBGene00006498(ten-1) "ENSXETG00000016434(ODZ2),ENSXETG00000015288(ODZ4)" "ENSMUSG00000049336(Odz2),ENSMUSG00000031561(Odz3),ENSMUSG00000048078(Odz4),ENSMUSG00000016150(Odz1)" "ENSG00000145934(ODZ2),ENSG00000218336(ODZ3),ENSG00000149256(ODZ4),ENSG00000009694(ODZ1)" " pupal stage , embryonic stage | stage 12-13 , embryonic stage | stage 12 , adult stage , embryonic stage | stage 13 , embryonic stage | stage 5-8 , larval stage--pupal stage , embryonic stage , embryonic stage | 5.5-7.5 hr , larval stage , embryonic stage | 9.5 hr , embryonic stage | 0-12 hr , embryonic stage | stage 10 " " cardioblast

, lymph gland

, supraesophageal ganglion

, imaginal disc

,

segmentally repeated , embryonic central nervous system

, trachea

, ventral nerve cord

, posterior spiracle primordium

" " embryonic stage | 4.5-7.5 hr , embryonic stage | stage 15 , embryonic stage | stage 12-15 , embryonic stage | 5.5-7.5 hr , embryonic stage | stage 8 , embryonic stage | 9.5 hr , embryonic stage | stage 12 , pupal stage , larval stage , embryonic stage | 2.5-3.5 hr , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 8-9 , embryonic stage | stage 9 , embryonic stage | stage 11 , embryonic stage | stage 11-12 , embryonic stage | stage 6 , embryonic stage | stage 10 , embryonic stage | stage 5 " "

segmentally repeated , visceral mesoderm

, posterior commissure

, mesoderm

segmentally repeated , posterior transverse furrow

, cardioblast

, neuron | restricted

, eye

, embryonic central nervous system | restricted

, neuron

, muscle attachment site

, ventral nerve cord

, posterior midgut proper primordium

, lymph gland | presumptive

, anterior commissure

, mesoderm

, stomodeum

, tracheal system

, longitudinal connective

, procephalic neurogenic region

, anterior transverse furrow

, imaginal disc

" "neuroanatomy defective,somatic clone,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive" "ommatidium,eye photoreceptor cell,interommatidial bristle,supernumerary,intersegmental nerve,intersegmental nerve | embryonic stage,NMJ bouton,somatic clone,lens,photoreceptor cell R7" FBgn0003326 sca scabrous http://flybase.net/reports/FBgn0003326.html FBgn0025943 protein_coding_gene 0004871=signal transducer activity "0016318=ommatidial rotation, 0046331=lateral inhibition, 0016321=female meiosis chromosome segregation, 0045468=regulation of R8 cell spacing in compound eye, 0048749=compound eye development, 0008587=imaginal disc-derived wing margin morphogenesis, 0007399=nervous system development, 0097305=response to alcohol, 0008407=chaeta morphogenesis, 0007460=R8 cell fate commitment" "0005576=extracellular region, 0005577=fibrinogen complex" "Sca, Scabrous, Fibrinogen-related protein, Sca1b, mAb sca1, clone 38, FBpp0086968, AAF58455, FBpp0086969, CG17579, AAA28880, anon-EST:Liang-38" "IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR020837=Fibrinogen, conserved site, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG17579 16-Dec-15 2015_12 "ENSDARG00000003025,ENSDARG00000012071(angptl1)" ENSG00000171560(FGA) " embryonic stage | stage 9,10 , embryonic stage , embryonic stage | stage 5 , embryonic stage | stage 5-8 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 10-11 , embryonic stage | stage 12 , embryonic stage | stage 10,11 " " neuroblast

, neuron

,

ubiquitous , central nervous system

, ventral neurogenic region

, peripheral nervous system

, optic lobe

, ventral nerve cord

, mechanosensory chaeta

, C1 chordotonal organ precursor cell

, photoreceptor cell R8 | presumptive

, eye-antennal disc

, ventral midline

, sensory mother cell

, sense organ | precursor embryonic thorax

, dorsal mesothoracic disc

, epidermoblast

" " larval stage | third instar , embryonic stage , larval stage " " photoreceptor cell R8

, central nervous system

, imaginal disc

, morphogenetic furrow | anterior to

, eye disc

, epidermis

, peripheral nervous system

, eye disc && morphogenetic furrow | posterior to

, photoreceptor cell R8 | presumptive

, photoreceptor cell R8 | vicinity of

, morphogenetic furrow | restricted

" "partially lethal - majority die,visible,wild-type,smell perception defective,learning defective,lethal,recessive,planar polarity defective,meiotic cell cycle defective,dominant,cell non-autonomous,somatic clone,cell polarity defective,some die during pupal stage" "eye,macrochaeta,adult thorax & macrochaeta,ommatidium,photoreceptor cell R8,eye disc,microchaeta & mesothoracic tergum,supernumerary,eye photoreceptor cell,scutum & macrochaeta,leg & macrochaeta,wing & macrochaeta,dorsocentral bristle,ectopic,scutellar bristle,chemosensory ventral triple row & microchaeta | ectopic,dorsal triple row & microchaeta | ectopic,cell non-autonomous,somatic clone,morphogenetic furrow & filopodium | somatic clone,microchaeta,acrostichal bristle,external sensory organ,tormogen cell,trichogen cell,eo neuron,external sensory organ precursor cell,adult cuticle,adherens junction,septate junction,sensory mother cell,microchaeta & mesothoracic tergum | supernumerary | somatic clone,antennal sense organ,sternopleural bristle,metathoracic coxal sensillum trichodeum,photoreceptor,wing,wing vein,wing margin,distal" FBgn0024846 p38b p38b MAP kinase http://flybase.net/reports/FBgn0024846.html "FBgn0014421, FBgn0024951, FBgn0027921" protein_coding_gene "0004707=MAP kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0016909=SAP kinase activity" "0007623=circadian rhythm, 0042594=response to starvation, 0072593=reactive oxygen species metabolic process, 0038001=paracrine signaling, 0006952=defense response, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 0009617=response to bacterium, 0009651=response to salt stress, 0001934=positive regulation of protein phosphorylation, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0000165=MAPK cascade, 0003007=heart morphogenesis, 0045088=regulation of innate immune response, 0006955=immune response, 1900407=regulation of cellular response to oxidative stress, 0009408=response to heat, 0071243=cellular response to arsenic-containing substance, 0042542=response to hydrogen peroxide, 0034614=cellular response to reactive oxygen species, 0050832=defense response to fungus, 0030510=regulation of BMP signaling pathway, 0042742=defense response to bacterium, 0007476=imaginal disc-derived wing morphogenesis, 0071276=cellular response to cadmium ion, 0045793=positive regulation of cell size, 0040018=positive regulation of multicellular organism growth, 0007179=transforming growth factor beta receptor signaling pathway, 2000331=regulation of terminal button organization" 0005634=nucleus "dp38b, ESTS:186F5S, p38B, p38b, p38beta, p38 MAP Kinase, Dp38b, p38 MAPK, 186F5S, Mpk34C, stress-activated p38b MAP kinase, p38 mitogen-activated protein kinase, MAPK, Dp38, p38 beta, Dm p38b, CG7393, BG:DS00797.3, p38, p38Kb, D-p38b, D-p38, anon-sts23, D-p38 MAPK, Dmp38b" "IPR017441=Protein kinase, ATP binding site, IPR008352=Mitogen-activated protein (MAP) kinase, p38, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG7393 16-Dec-15 2015_12 "ENSDARG00000028721(mapk14b),ENSDARG00000045836(zgc:86905)" YLR113W(HOG1) WBGene00004055(pmk-1) ENSXETG00000022254(MAPK11) "ENSMUSG00000053436(Mapk14),ENSMUSG00000053137(Mapk11)" "ENSG00000112062(MAPK14),ENSG00000185386(MAPK11)" embryonic stage " anterior embryonic/larval midgut

,

ubiquitous , posterior embryonic/larval midgut

" "neuroanatomy defective,immune response defective,developmental rate defective,melanotic mass phenotype,drug conditional,partially lethal - majority die,recessive,starvation stress response defective,heat stress response defective,osmotic stress response defective,small body,decreased cell size,nutrition conditional,visible,oxidative stress response defective,long lived,viable,short lived,locomotor behavior defective,RU486 conditional" "NMJ bouton,embryonic/larval hindgut,drug conditional,posterior,nutrition conditional,wing vein,ectopic,wing,NMJ bouton | larval stage,adult heart,RU486 conditional" FBgn0003310 S Star http://flybase.net/reports/FBgn0003310.html "FBgn0010102, FBgn0010674, FBgn0069199" protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 0007173=epidermal growth factor receptor signaling pathway, 0016318=ommatidial rotation, 0038004=epidermal growth factor receptor ligand maturation, 0035225=determination of genital disc primordium, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0001751=compound eye photoreceptor cell differentiation, 0000042=protein targeting to Golgi, 0048865=stem cell fate commitment, 0048477=oogenesis, 0042058=regulation of epidermal growth factor receptor signaling pathway, 0045467=R7 cell development, 0046667=compound eye retinal cell programmed cell death, 0042051=compound eye photoreceptor development, 0007421=stomatogastric nervous system development, 0048149=behavioral response to ethanol" "0016020=membrane, 0005886=plasma membrane, 0005794=Golgi apparatus, 0005783=endoplasmic reticulum, 0097038=perinuclear endoplasmic reticulum" "E(Raf)2B, Star, l(2)rK134, l(2)c00080, l(2)05671, EC2-2, Enhancer of GMR-sina 2-4, ES2-4, EK2-2, unnamed, floater, CG4385, l(2)07056, fltr, Star/asteroid, l(2)21Eb, EY2-4, l(2)k09538, lethal (2) c00080, star" CG4385 16-Dec-15 2015_12 " embryonic stage , larval stage | third instar " " midline glial cell

, mesectoderm

, eye-antennal disc

, photoreceptor cell R5 | presumptive

, morphogenetic furrow

, photoreceptor cell R2 | presumptive

, photoreceptor cell R8 | presumptive

, embryonic optic lobe primordium

" "lethal,recessive,visible,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical sensitive,cell polarity defective,female fertile,maternal effect,germline clone,female sterile,decreased cell number,viable,female sterile soma-dependent,increased cell death,neuroanatomy defective,wild-type" "presumptive embryonic/larval central nervous system,denticle belt,eye,photoreceptor cell R2,photoreceptor cell R5,photoreceptor cell R8,wing vein L2,wing vein L3,wing vein L4,wing vein L5,ommatidium,photoreceptor,mesothoracic tibial bract,mesothoracic tarsal segment 1 & bract,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,fascicle,wing,eye photoreceptor cell,somatic clone,midline glial cell,dorsal neurohemal organ,wing vein,germline clone,macrochaeta,embryonic/first instar larval cuticle,maternal effect,interommatidial bristle,ovariole,dorsal appendage,photoreceptor cell R7,longitudinal connective,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,MP1 neuron,anterior commissure,posterior commissure,ventral,Keilin's organ,lamellocyte,conditional,VUM neuron,embryonic ventral nervous system,anal pad,cephalopharyngeal skeleton,larval sense organ & antennal segment,larval sense organ & maxillary segment,commissure,sensory neuron,motor neuron,egg chamber,dorsocentral bristle,scutellar bristle,nurse cell,oocyte,photoreceptor cell,inter-ommatidial precursor cell,embryonic/larval stomatogastric nervous system,stomodeal invagination,embryonic ventral epidermis,genital disc primordium,embryonic/larval somatic muscle,ventral nerve cord,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,midline ventral glial cell,embryonic/larval dorsal trunk,embryonic/larval trachea,lch5 neuron,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,optic cartridge,wing margin,ectopic" FBgn0026598 Apc2 Adenomatous polyposis coli tumor suppressor homolog 2 http://flybase.net/reports/FBgn0026598.html protein_coding_gene "0008017=microtubule binding, 0008013=beta-catenin binding, 0005515=protein binding" "0007405=neuroblast proliferation, 0030178=negative regulation of Wnt signaling pathway, 0007447=imaginal disc pattern formation, 0040001=establishment of mitotic spindle localization, 0030951=establishment or maintenance of microtubule cytoskeleton polarity, 0000281=mitotic cytokinesis, 0030866=cortical actin cytoskeleton organization, 0045732=positive regulation of protein catabolic process, 0035190=syncytial nuclear migration, 0035293=chitin-based larval cuticle pattern formation, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0016055=Wnt signaling pathway, 0045862=positive regulation of proteolysis, 0016337=single organismal cell-cell adhesion, 0007017=microtubule-based process, 0030589=pseudocleavage involved in syncytial blastoderm formation, 0007155=cell adhesion, 0030111=regulation of Wnt signaling pathway, 0007411=axon guidance, 0007420=brain development, 0045892=negative regulation of transcription, DNA-templated, 0008362=chitin-based embryonic cuticle biosynthetic process, 0021550=medulla oblongata development, 0008258=head involution" "0043025=neuronal cell body, 0005912=adherens junction, 0005875=microtubule associated complex, 0005938=cell cortex, 0030425=dendrite, 0045179=apical cortex, 0005884=actin filament, 0043234=protein complex, 0032154=cleavage furrow, 0030877=beta-catenin destruction complex, 0045180=basal cortex, 0016327=apicolateral plasma membrane, 0005634=nucleus, 0005737=cytoplasm" "dApc2, dapc2, Dm APC2, CG6193, dAPC2, apc2, E-APC dAPC2, E-APC, d-APC2, APC, e-apc, Epithelial Adenomatous Polyposis Coli, APC2, Adenomatous polyposis coli 2, dAPC2/E-APC, D-APC2, Adenomatous Polyposis Coli 2, adenomatous polyposis coli 2" "IPR009223=Adenomatous polyposis coli protein, cysteine-rich repeat, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR000225=Armadillo, IPR026818=Adenomatous polyposis coli (APC) family, IPR009240=Adenomatous polyposis coli protein, 15 residue repeat" CG6193 16-Dec-15 2015_12 ENSDARG00000063007(apc2) "wild-type,viable,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,germline clone,partially lethal - majority live,lethal,recessive,heat sensitive,maternal effect,sterile,visible,non-rescuable maternal effect" "denticle,supernumerary,denticle belt,embryonic/first instar larval cuticle,embryonic/larval cuticle,maternal effect,hub cell,male germline stem cell,nucleus | embryonic stage 4 | germline clone,actin filament | embryonic stage 4 | germline clone,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,spindle & syncytial blastoderm embryo | maternal effect,organism | embryonic stage 4,cortical actin cytoskeleton,epithelial cell,syncytial blastoderm embryo,germline clone,spindle | embryonic stage 4 | germline clone,egg chamber,oocyte,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,heat sensitive,dorsal fine hair,male germline stem cell & spindle,male germline stem cell & centrosome,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,wing vein,ommatidium,chaeta,nurse cell,nurse cell & plasma membrane,spot adherens junction,plasma membrane,embryonic epidermis,midgut constriction 1" FBgn0003270 amos absent MD neurons and olfactory sensilla http://flybase.net/reports/FBgn0003270.html "FBgn0003689, FBgn0027104" protein_coding_gene "0046982=protein heterodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0001012=RNA polymerase II regulatory region DNA binding" "0007399=nervous system development, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0008052=sensory organ boundary specification, 0016360=sensory organ precursor cell fate determination, 0007423=sensory organ development" 0005634=nucleus "Amos, absent md neurons and olfactory sensilla, Rough-eye, Roi, bHLHa10, Rough eye, CG10393, rolo, Tft, amos, Tufted, asolo, Absent MD neurons" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG10393 16-Dec-15 2015_12 "ENSDARG00000030402(twist1a),ENSDARG00000019646(twist3),ENSDARG00000031277(twist1b)" ENSXETG00000023279(ATOH1) ENSMUSG00000007805(Twist2) " embryonic stage , adult stage && oogenesis stage , pupal stage , pupal stage | 0-4 hr , embryonic stage | stage 10 , embryonic stage | stage 5 , embryonic stage | blastoderm " " embryonic labial segment | restricted

, abdominal segment | restricted

, centripetally migrating follicle cell

, antennal disc

, tarsus | anlagen

, olfactory sensory organ | anlagen

, antenno-maxillary complex | anlagen

, embryonic labial segment

, nurse cell

, oocyte

, thoracic segment | restricted

, antenno-maxillary complex | restricted

, embryonic antennal segment

,

, embryonic mandibular segment

, sensory mother cell

,

ubiquitous , embryonic antennal segment | restricted

" "viable,visible,lethal,recessive,dominant,neuroanatomy defective,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,dorsal abdominal cluster,dorsal multidendritic neuron,abdominal dorsal bipolar neuron dbp,ommatidium,eye disc,rhabdomere,cone cell,eye photoreceptor cell,supernumerary,pigment cell,somatic clone,rhabdomere R7,rhabdomere R8,mesothoracic metatarsus,mesothoracic tarsal bristle,chaeta,ectopic,tormogen cell,adult mesothoracic segment,metathoracic laterotergite,scutellum,sensory mother cell,wing disc,macrochaeta,antennal sense organ,microchaeta,mesothoracic tergum,postalar bristle,dorsocentral bristle,scutellar bristle,sensory neuron,dorsal,sensillum basiconicum & antenna,sensillum trichodeum of antennal segment 3,macrochaeta | ectopic & antenna,sensory mother cell & antennal disc,embryonic antennal sense organ,olfactory neuron & embryonic antennal sense organ,sensillum basiconicum & antennaM36F-S6),macrochaeta | ectopic & antennaM36F-S6),olfactory receptor neuron,antenna,sensillum basiconicum of antennal segment 3,sensillum coeloconicum of antennal segment 3,sense organ,scutellum & chordotonal organ | ectopic-109-68,wing vein L3 & chordotonal organ | ectopic-109-68,wing vein L3 & external sensory organ | ectopic-109-68,adult thorax & olfactory sensory organ | ectopic-109-68,adult head & olfactory sensory organ | ectopic-109-68,wing vein L3 & olfactory sensory organ | ectopic-109-68,microchaeta & adult thorax-109-68,adult thorax & macrochaeta-109-68,antennal segment 1 & olfactory sensory organ | ectopichs.PB,antennal segment 2 & olfactory sensory organ | ectopichs.PB,sensillum campaniformium,mechanosensory chaeta,sensory mother cell | ectopic & dorsal mesothoracic discdpp.blk1,macrochaeta | ectopic & adult headC-765,macrochaeta | ectopic & mesothoracic tergumC-765,sensillum campaniformium | ectopic & wingC-765,wing sensillum,multidendritic neuron,scolopidial neuron,ventral multidendritic neuron,embryonic/larval neuron,dorsal multidendritic neuron ddaC" FBgn0015805 HDAC1 Histone deacetylase 1 http://flybase.net/reports/FBgn0015805.html "FBgn0003632, FBgn0003634, FBgn0010843, FBgn0016893" protein_coding_gene "0004407=histone deacetylase activity, 0003714=transcription corepressor activity, 0005515=protein binding" "2001229=negative regulation of response to gamma radiation, 0070983=dendrite guidance, 0008340=determination of adult lifespan, 0048477=oogenesis, 0006355=regulation of transcription, DNA-templated, 0035065=regulation of histone acetylation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0022008=neurogenesis, 0007350=blastoderm segmentation, 0045892=negative regulation of transcription, DNA-templated, 0007517=muscle organ development, 0016458=gene silencing, 0050771=negative regulation of axonogenesis, 0045879=negative regulation of smoothened signaling pathway, 0006342=chromatin silencing, 0016575=histone deacetylation, 0006099=tricarboxylic acid cycle, 0048813=dendrite morphogenesis, 0022904=respiratory electron transport chain" "0016581=NuRD complex, 0000785=chromatin, 0005705=polytene chromosome interband, 0016580=Sin3 complex, 0035098=ESC/E(Z) complex, 0005700=polytene chromosome, 0031523=Myb complex, 0017053=transcriptional repressor complex, 0070822=Sin3-type complex, 0005634=nucleus" "DmHDAC1, rpd3, drpd3, Su(var)328, Histone Deacetylase-1, HDAC1, l(3)04556, DRpd3, rpd[3], histone deacetylase 1, dHDAC1, Histone Deacetylase 1, histone deacetylase, Su(var)3-26, hdac1, Suppressor of variegation 326, E(var)3-64BC, HDAC, dRpd3, RPD3, Rpd3/HDAC, Rpd3, Histone Deacetylase 1 (HDAC1), Hdac, DHDAC1, HDAC-1, l(3)64Cc, dmHDA401, dHDAC-1, dRPD3, Hdac1, Rpd3 histone deacetylase, Su(var)326, CG7471, reduced potassium dependency 3" "IPR000286=Histone deacetylase superfamily, IPR003084=Histone deacetylase, IPR023801=Histone deacetylase domain" CG7471 16-Dec-15 2015_12 ENSDARG00000015427(hdac1) YNL330C(RPD3) WBGene00001834(hda-1) "ENSXETG00000005253(hdac1),ENSXETG00000007339(hdac2)" "ENSMUSG00000019777(Hdac2),ENSMUSG00000028800(Hdac1),ENSMUSG00000061062(Gm10093)" "ENSG00000196591(HDAC2),ENSG00000116478(HDAC1)" " larval stage , embryonic stage&&larval stage&&adult stage " eye-antennal disc

"lethal,suppressor of variegation,recessive,polyphasic,maternal effect,poor,partially lethal - majority die,visible,drug conditional,long lived,dominant,male,female,pair rule phenotype,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,enhancer of variegation,viable,fertile,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell number,mitotic cell cycle defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell death" "cuticle,maternal effect,wing,macrochaeta,alula,sex comb,drug conditional,cephalopharyngeal skeleton,germline clone,denticle belt,embryonic epidermis,embryonic segment,embryo,segment,ommatidium,adult antennal lobe projection neuron DL1 adPN,somatic clone,wing disc,projection neuron,mesothoracic tergum,ganglion mother cell" DRSC08696 K 0.252249731 -1.023636735 -1.235260356 -0.33432081 0.92010934 2.721467973 FBgn0011217 eff effete http://flybase.net/reports/FBgn0011217.html "FBgn0004831, FBgn0011011, FBgn0011333, FBgn0011657, FBgn0013661, FBgn0013663, FBgn0013935, FBgn0062081" protein_coding_gene "0061631=ubiquitin conjugating enzyme activity, 0005515=protein binding, 0031625=ubiquitin protein ligase binding, 0004842=ubiquitin-protein transferase activity, 0061630=ubiquitin protein ligase activity" "0007286=spermatid development, 0000209=protein polyubiquitination, 0031647=regulation of protein stability, 0007140=male meiosis, 0007067=mitotic nuclear division, 0001751=compound eye photoreceptor cell differentiation, 0030718=germ-line stem cell maintenance, 0051276=chromosome organization, 0022008=neurogenesis, 0045676=regulation of R7 cell differentiation, 0006511=ubiquitin-dependent protein catabolic process, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0048477=oogenesis, 0016567=protein ubiquitination, 0048132=female germ-line stem cell asymmetric division, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation, 0016322=neuron remodeling, 0001745=compound eye morphogenesis" 0005875=microtubule associated complex "ms(3)neo2, Ubiquitin conjugating enzyme 1, E(Pc)88D, UBCD-1, l(3)01462, UBCD1, ms(3)ry3, 3527, ms(3)01295, ms(3)ry1, ms(3)1, ms(3)3, meiotic 68, UBC4, 6535, ms(3)88D, l(3)s1782, CG7425, UbcD1, Suppressor of GMR-sina 3-3, Effete, Eff, SS3-3, effete, EFF, Ubc-D1, ubcD1, UbcD, effette, l(3)j2C8, mei68, anon-WO0118547.343, fs(3)01295" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site" CG7425 16-Dec-15 2015_12 "ENSDARG00000028252(zgc:55886),ENSDARG00000015057(ube2d4)" "YDR059C(UBC5),YBR082C(UBC4)" WBGene00002344(let-70) ENSXETG00000021323(ube2d2) "ENSMUSG00000037096(Gm9762),ENSMUSG00000078578(Ube2d3)" ENSG00000078967(UBE2D4) " embryonic stage | early , embryonic stage -- adult stage , adult stage | male " "lethal,viable,fertile,male sterile,recessive,female sterile,female fertile,mitotic cell cycle defective,neuroanatomy defective,somatic clone,partially lethal - majority die,meiotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,poor,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,dominant" "testis,female germline stem cell,egg chamber & cell,egg chamber & mitotic cell cycle,nurse cell fusome,mitosis & chromosome, telomeric region,nurse cell & nucleus,neuroblast,somatic clone,germarium,germline clone,macrochaeta,meiosis & chromosome, telomeric region | male,meiosis & nuclear chromosome | male,dendrite,neuron,ectopic,nuclear chromosome,eye,eye photoreceptor cell,pigment cell,sex comb,mesothoracic leg,dorsal multidendritic neuron ddaC,ganglion mother cell" FBgn0013984 InR Insulin-like receptor http://flybase.net/reports/FBgn0013984.html "FBgn0000456, FBgn0000457, FBgn0002393, FBgn0010868" protein_coding_gene "0004713=protein tyrosine kinase activity, 0005009=insulin-activated receptor activity, 0043560=insulin receptor substrate binding, 0043548=phosphatidylinositol 3-kinase binding, 0005520=insulin-like growth factor binding, 0043559=insulin binding, 0005515=protein binding, 0005524=ATP binding" "0048133=male germ-line stem cell asymmetric division, 0007623=circadian rhythm, 0007584=response to nutrient, 0046622=positive regulation of organ growth, 0006974=cellular response to DNA damage stimulus, 0046777=protein autophosphorylation, 0008361=regulation of cell size, 0007626=locomotory behavior, 0060250=germ-line stem-cell niche homeostasis, 2000252=negative regulation of feeding behavior, 0042220=response to cocaine, 0007390=germ-band shortening, 0007446=imaginal disc growth, 0007520=myoblast fusion, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 2000377=regulation of reactive oxygen species metabolic process, 0007568=aging, 0036335=intestinal stem cell homeostasis, 0042127=regulation of cell proliferation, 0010507=negative regulation of autophagy, 0048589=developmental growth, 0030307=positive regulation of cell growth, 0016049=cell growth, 0008286=insulin receptor signaling pathway, 0035264=multicellular organism growth, 0051290=protein heterotetramerization, 0034059=response to anoxia, 0005975=carbohydrate metabolic process, 0046620=regulation of organ growth, 0090278=negative regulation of peptide hormone secretion, 0006629=lipid metabolic process, 0060180=female mating behavior, 0016322=neuron remodeling, 0007285=primary spermatocyte growth, 0007391=dorsal closure, 0008284=positive regulation of cell proliferation, 0007411=axon guidance, 0042321=negative regulation of circadian sleep/wake cycle, sleep, 0007525=somatic muscle development, 0040007=growth, 0006979=response to oxidative stress, 0007296=vitellogenesis, 0008585=female gonad development, 0045793=positive regulation of cell size, 0048132=female germ-line stem cell asymmetric division, 0040014=regulation of multicellular organism growth, 0040018=positive regulation of multicellular organism growth, 0001700=embryonic development via the syncytial blastoderm" "0005886=plasma membrane, 0005887=integral component of plasma membrane, 0005899=insulin receptor complex, 0005911=cell-cell junction" "dir, inR, insulin receptor homologue, Insulin-receptor, lethal(3)93Dj, InsR, insulin receptor homolog, IR, dInR, DIRH, 18402, insulin-receptor, er10, insulin-like receptor, Inr-beta, Insulin receptor, INS, l(3)05545, dINR, insulin receptor, INR, DIHR, l(3)93Dj, dIRH, dinr, Inr-alpha, inr, DIR, DILR, DInr, Drosophila Insulin Receptor, Insulin, DIRbeta, insulin/insulin-like growth factor receptor, Inr, Insulin-like Receptor, Drosophila insulin receptor, CG18402, dInsR, l(3)er10, Dir-b, Insulin Receptor, Dir-a, DInR, lnR, dIR, dInr" "IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR006211=Furin-like cysteine-rich domain, IPR017441=Protein kinase, ATP binding site, IPR006212=Furin-like repeat, IPR003961=Fibronectin type III, IPR013783=Immunoglobulin-like fold, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR000494=Receptor L-domain, IPR002011=Tyrosine-protein kinase, receptor class II, conserved site, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain" CG18402 16-Dec-15 2015_12 "ENSDARG00000027423(igf1ra),ENSDARG00000034434(igf1rb),ENSDARG00000011948(insra),ENSDARG00000071524(insrb)" WBGene00000898(daf-2) "ENSXETG00000002112(IGF1R),ENSXETG00000018010(INSRR)" "ENSMUSG00000005533(Igf1r),ENSMUSG00000005534(Insr),ENSMUSG00000005640(Insrr)" "ENSG00000140443(IGF1R),ENSG00000171105(INSR),ENSG00000027644(INSRR)" embryonic stage -- adult stage embryonic stage " neuroblast

, embryonic/larval hindgut

, posterior midgut proper primordium

, ventral nerve cord | segmentally repeated

, supraesophageal ganglion

, epidermis

" "neuroanatomy defective,lethal,recessive,lethal - all die before end of second instar larval stage,some die during second instar larval stage,heat sensitive,short lived,visible,small body,partially lethal,male,viable,female,developmental rate defective,starvation stress response defective,long lived,female sterile,male sterile,partially,somatic clone,dominant,chemical sensitive,melanotic mass phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,hyperplasia,decreased cell size,decreased cell number,cell autonomous,stress response defective,cell number defective,cell size defective,size defective,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,sleep defective,mating defective,body size defective,conditional,RU486 conditional,feeding behavior defective,increased cell size,aging defective,oxidative stress response defective,circadian rhythm defective,partially lethal - majority die,some die during pupal stage" "lamina anlage,photoreceptor cell & axon,medulla anlage,segment border muscle,A1-7 dorsal acute muscle 1,embryonic/larval somatic muscle,embryonic myoblast,eye,mushroom body,gamma Kenyon cell,male germline stem cell,polar primary spermatocyte,primary spermatocyte,adult gut,ommatidium,somatic clone,longitudinal connective,commissure,fascicle,embryonic/larval brain,melanotic mass,wing,amnioserosa,germline cyst,germline clone,female germline stem cell,egg chamber,rhabdomere,germarium cap cell,ovariole,wing disc,haltere disc,mesothoracic leg disc,metathoracic leg disc,eye-antennal disc,ovary,gonadal sheath proper primordium,terminal filament,adult heart,heat sensitive,maxillary palpus,genital arch,wing vein,ectopic,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,extended germ band embryo,embryonic/first instar larval cuticle,embryonic head,head capsule,eye disc,lamina neuropil,embryonic/larval optic lobe,medulla,photoreceptor cell,wing blade,embryonic/larval neuroblast,posterior,embryonic/larval oenocyte,mushroom body neuroblast,adult fat body,RU486 conditional,dorsal multidendritic neuron ddaC | pupal stage,ectopic | larval stage,mitotic cell cycle | somatic clone,embryonic/larval digestive system,embryonic/larval Malpighian tubule,embryonic/larval epidermis,embryonic/larval fat body,chaeta,coxa,proximal,sensillum trichodeum,supernumerary,arista,third segment of antenna,capitellum,haltere pedicel,gonopod thorn bristle,1st posterior cell,fat body,lipid particle | somatic cloneë±Tub84B.PP,ellipsoid body,neuron,synapse | supernumeraryD42,trichogen cell,synapse,neuromuscular junction,embryonic/larval hemocyte | third instar larval stage" DRSC16717 I -0.660553829 -2.960069415 -0.570140897 -0.033232824 -0.180366219 -0.341369813 FBgn0000341 Coa Coarse http://flybase.net/reports/FBgn0000341.html gene 16-Dec-15 2015_12 visible wing & macrochaeta FBgn0001180 hb hunchback http://flybase.net/reports/FBgn0001180.html FBgn0015224 protein_coding_gene "0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0007400=neuroblast fate determination, 0007424=open tracheal system development, 0008293=torso signaling pathway, 0040034=regulation of development, heterochronic, 0044324=regulation of transcription involved in anterior/posterior axis specification, 0007362=terminal region determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0035289=posterior head segmentation, 0007419=ventral cord development, 0007355=anterior region determination, 0007354=zygotic determination of anterior/posterior axis, embryo, 0007431=salivary gland development, 0048699=generation of neurons, 0001763=morphogenesis of a branching structure, 0007402=ganglion mother cell fate determination, 0007427=epithelial cell migration, open tracheal system, 0008595=anterior/posterior axis specification, embryo, 0035290=trunk segmentation" 0005634=nucleus "l(3)85Ah, Rg-bx, R-pbx, Regulator-of-postbithorax, HUNCHBACK, CG9786, Hb, Hunchback, HB, hbHLH, Rg-pbx" "IPR027742=Protein hunchback, IPR027775=C2H2- zinc finger protein family, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG9786 16-Dec-15 2015_12 "ENSDARG00000013539(ikzf1),ENSDARG00000069111" WBGene00001824(hbl-1) ENSXETG00000009559(znfn1a5) ENSMUSG00000040167(Ikzf5) ENSG00000095574(IKZF5) " embryonic stage | embryonic cycle 13 , embryonic stage | stage 4 , embryonic stage | early , embryonic stage | 2-6hr , embryonic stage | embryonic cycle 14 , adult stage | female , embryonic stage | stage >8 , adult stage && oogenesis stage | stage S7-11 , embryonic stage | 0-8hr , embryonic stage | embryonic cycle 11-13 " " organism | 0-30% egg length

,

anterior ,

50-100% egg length , organism | 10-30% egg length

, embryonic central nervous system

,

0-10% egg length , nurse cell

,

posterior , organism | 50-100% egg length

,

0-20% egg length , organism | 0-20% egg length

, organism | 50-90% egg length

" " embryonic stage | early , embryonic stage | stage 9-11 , embryonic stage , embryonic stage | stage 15-17 , embryonic stage | stage 4 , oogenesis stage " "

~30-100% egg length{ + pum13 } , tritocerebral neuroblast | subset

, neuroblast

{ $ l(1)sc- } ,

~30-100% egg length{ + pumMsc } , deuterocerebral neuroblast | subset

, EW1 neuron

,

anterior ,

, neuroblast

, protocerebral neuroblast | subset

, organism | 50-100% egg length ,

0-20% egg length ,

~70-100% egg length{ + pum1 } ,

posterior ,

anterior{ + osk*, nosbcd.3UTR } , GW neuron

, ubiquitous

{ + pumFC8 } " "embryonic/larval segmentation phenotype,viable,fertile,neuroanatomy defective,heat sensitive,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,maternal effect,dominant,lethal,female,lethal - all die before end of larval stage,some die during larval stage,homeotic,pair rule phenotype,visible,some die during pupal stage" "embryonic head,embryonic thoracic segment,embryonic abdominal segment,U neuron,supernumerary,U5 neuron,U3 neuron,U1 neuron,U2 neuron,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic mesothoracic segment,abdomen,ectopic,heat sensitive,pole cell,embryonic metathoracic segment,embryonic epidermis,embryonic prothoracic segment,maternal effect,EW2 neuron,EW1 neuron,ganglion mother cell GMC1-1a,aCC neuron,RP2 motor neuron,motor neuron,medial-most cell body glial cell,abdominal segment,filzkorper,parasegment 6,parasegment 13,embryonic abdominal segment 4,embryonic abdominal segment 2,posterior,cephalopharyngeal skeleton,embryo,embryonic gnathal segment,haltere,metathoracic segment,adult metathoracic segment,embryonic/larval dorsal trunk,embryonic labial segment,mouth hooks,larval labial segment,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,larval abdominal segment 7,larval abdominal segment 8,thorax,prothoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 3,central nervous system,brain,gnathal segment,abdominal segment 8,adult salivary gland primordium,neuroblast NB7-3,GW neuron,neuroblast NB7-1,fpCC neuron,pCC neuron,embryonic/first instar larval cuticle,embryonic abdomen,anterior,abdominal 8 ventral denticle belt,mesothoracic segment,abdominal segment 1,hypostomal sclerite,embryonic/larval labial segment sensillum,larval head,extended germ band embryo,longitudinal connective,commissure,embryonic neuroblast,ectopic | embryonic stage,embryonic/larval esophagus | embryonic stage,median tooth,epipharyngeal sclerite,dorsal bridge,embryonic/larval pharynx | embryonic stage,gastric caecum,embryonic/larval proventriculus | embryonic stage,precursor cell of the stomatogastric nervous system,dorsal arm of pharyngeal sclerite,ventral arm of pharyngeal sclerite,U4 neuron,FMRFamide SE2 neuron,eye,antennal lobe neuroblast,somatic clone" DRSC16963 K -0.647216458 -0.26055423 0.986051002 0.308954246 0.135749835 1.638106134 FBgn0051947 CG31947 http://flybase.net/reports/FBgn0051947.html protein_coding_gene 16-Dec-15 2015_12 FBgn0000432 dep depressed http://flybase.net/reports/FBgn0000432.html gene 16-Dec-15 2015_12 visible wing FBgn0051205 CG31205 http://flybase.net/reports/FBgn0051205.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site" CG31205 16-Dec-15 2015_12 "viable,fertile" FBgn0061138 l(3)S000627c lethal (3) S000627c http://flybase.net/reports/FBgn0061138.html gene 27-Jun 16-Dec-15 2015_12 lethal FBgn0040805 CG12355 http://flybase.net/reports/FBgn0040805.html protein_coding_gene "0016021=integral component of membrane, 0005777=peroxisome" unnamed IPR007248=Mpv17/PMP22 CG12355 16-Dec-15 2015_12 ENSXETG00000024674(MPV17L) ENSMUSG00000022679(Mpv17l) ENSG00000156968(MPV17L) viable FBgn0003028 ovo ovo http://flybase.net/reports/FBgn0003028.html "FBgn0000825, FBgn0000849, FBgn0003650, FBgn0029741" protein_coding_gene "0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0046872=metal ion binding" "0048477=oogenesis, 0016348=imaginal disc-derived leg joint morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0009913=epidermal cell differentiation, 0048067=cuticle pigmentation, 0035316=non-sensory hair organization, 0007010=cytoskeleton organization, 0006355=regulation of transcription, DNA-templated, 0070896=positive regulation of transposon integration, 0008343=adult feeding behavior, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0035017=cuticle pattern formation, 0042335=cuticle development, 0042810=pheromone metabolic process, 0019099=female germ-line sex determination, 0018992=germ-line sex determination" 0005634=nucleus "ovo/shavenbaby, fs(1)M1, Svb, Fs(1)K1237, shavenbaby, ovo/svb, CG6824, Ovo, Svb/Ovo, OVO, CG15467, Fs(1)K155, ovo/shaven-baby, Shavenbaby, Ovo-D, Fs(1)K1103, svb, Shv, ovoD, fs(1)M38, fs(1)K1237, shaven baby" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR027756=Ovo/Ovo-like 1, IPR007087=Zinc finger, C2H2, IPR027775=C2H2- zinc finger protein family" CG6824 16-Dec-15 2015_12 YKL062W(MSN4) " oogenesis stage | stage S8 , embryonic stage | cellular blastoderm , embryonic stage | stage 14 , embryonic stage | stage 10-11 , embryonic stage | stage 13 , embryonic stage | stage 10 , embryonic stage | stage 17 , embryonic stage | mid , embryonic stage | stage 8 , embryonic stage | stage 1-2 , embryonic stage | stage 12 , embryonic stage | stage 6 , egg stage | unfertilized egg , oogenesis stage , embryonic stage | syncytial blastoderm , adult stage && oogenesis stage | stage S10 , embryonic stage | early , oogenesis stage | stage S10 && adult stage | female , adult stage && oogenesis stage , embryonic stage | stage 5-8 " " organism

,

ubiquitous , dorsal hair

, embryonic labial segment

, denticle belt | segmentally repeated

, antenna

, gonad

, denticle belt | restricted

, cephalic furrow | restricted

, intercalary segment

, organism | 60-80% egg length

, stomatogastric nervous system

, organism | segmentally repeated

, unfertilized egg

, pole cell

, egg chamber | early

, dorsal ridge

, nurse cell | restricted

, organism | 80-90% egg length

, nurse cell

, germarium

, embryonic/larval pharynx

, follicle cell

" " embryonic stage | stage 17 , adult stage && oogenesis stage , larval stage | first instar , oogenesis stage&&larval stage | second instar , embryonic stage | stage 8-14 , oogenesis stage&&larval stage | first instar , spermatogenesis && adult stage , oogenesis stage | stage S8 && adult stage | female , embryonic stage | blastoderm , oogenesis stage | stage S10 && adult stage | female , oogenesis stage&&larval stage | third instar " " germline cell

, female germline stem cell

, gonad

, female germline stem cell | restricted

, pole cell

, male germline stem cell

, nurse cell

,

ubiquitous , oocyte

" "lethal,polyphasic,female sterile,recessive,viable,fertile,male fertile,visible,cold sensitive,heat sensitive,female fertile,somatic clone,wild-type,dominant,cytokinesis defective,grandchildless,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,feeding behavior defective,decreased cell growth,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,adult thorax & trichome | somatic clone,adult thorax & microchaeta | somatic clone,dorsal fine hair,temperature conditional,ovary,germline cell,female,spectrosome,nurse cell fusome,nurse cell,germarium cap cell,eye,cold sensitive,embryonic/first instar larval cuticle,arista lateral,arista central core,leg,joint,denticle belt,ectopic,stage S6 oocyte,testis,egg,maternal effect,chorion,stage S4 oocyte,oocyte,dorsal appendage,denticle,embryonic epidermis,embryonic segment,embryonic head,cephalopharyngeal skeleton,adult abdomen & trichome | somatic clone,somatic clone,sternopleural bristle,male,sex comb,denticle row 2,denticle row 3,wing hair,adult thorax & trichomeBx-MS1096,trichome,precursor,ommatidium,interommatidial bristle,rhabdomereGMR.PF,tarsal segment,adult thorax & microchaetaBx-MS1096,denticle row 1,posterior compartment,filamentous actin & embryonic/first instar larval cuticle | ectopicptc-559.1,filamentous actin & embryonic/first instar larval cuticle | ectopic | somatic clone,supernumerary,chaeta,mesothoracic tergum" FBgn0001075 ft fat http://flybase.net/reports/FBgn0001075.html "FBgn0002120, FBgn0014266" protein_coding_gene "0005509=calcium ion binding, 0045296=cadherin binding, 0050839=cell adhesion molecule binding, 0004872=receptor activity" "0008285=negative regulation of cell proliferation, 0045926=negative regulation of growth, 0000904=cell morphogenesis involved in differentiation, 0045571=negative regulation of imaginal disc growth, 0007476=imaginal disc-derived wing morphogenesis, 0016318=ommatidial rotation, 0045317=equator specification, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0032880=regulation of protein localization, 0046620=regulation of organ growth, 0048105=establishment of body hair planar orientation, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0018149=peptide cross-linking, 0035159=regulation of tube length, open tracheal system, 0007164=establishment of tissue polarity, 0045198=establishment of epithelial cell apical/basal polarity, 0090176=microtubule cytoskeleton organization involved in establishment of planar polarity, 0016337=single organismal cell-cell adhesion, 0040008=regulation of growth, 0044331=cell-cell adhesion mediated by cadherin, 0007446=imaginal disc growth, 0001737=establishment of imaginal disc-derived wing hair orientation, 0001736=establishment of planar polarity, 0035329=hippo signaling, 0030178=negative regulation of Wnt signaling pathway, 0008283=cell proliferation, 0042067=establishment of ommatidial planar polarity, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" "0016021=integral component of membrane, 0005887=integral component of plasma membrane" "CG3352, 79/18, l(2)k07918, floppy-discs, fat, Dm Fat, l(2)ft, giant discs 2, l(2)24Da, giant-discs-1, l(2)fat, FAT, Ft, l(2)fd, l(2)gd2, l(2)gd-l, l(2)79/18, l(2)gd-1, CT11259, Fat" "IPR020894=Cadherin conserved site, IPR001791=Laminin G domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR013032=EGF-like, conserved site, IPR002126=Cadherin, IPR015919=Cadherin-like, IPR000742=EGF-like domain" CG3352 16-Dec-15 2015_12 WBGene00019994(cdh-1) ENSMUSG00000046743(Fat4) ENSG00000196159(FAT4) " embryonic stage , larval stage " " ectoderm

, embryonic/larval pharynx

, embryonic/larval hindgut

, neuron &&of larval optic lobe

, imaginal disc

, embryonic/larval foregut

" "lethal,recessive,visible,dominant,hyperplasia,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective,cell polarity defective,partially lethal - majority die,planar polarity defective,increased cell number,somatic clone,decreased cell number,lethal - all die before end of pupal stage,some die during pupal stage,cell non-autonomous,mitotic cell cycle defective,viable,developmental rate defective,decreased cell size,cell autonomous,lethal - all die before end of P-stage,some die during pharate adult stage,cell shape defective,cell growth defective,neuroanatomy defective,progressive,cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,wing,wing disc,external sensory organ,macrochaeta,microchaeta,eye disc,abdomen,embryonic/larval dorsal trunk,embryonic/larval glial cell,ommatidium,somatic clone,cell non-autonomous,photoreceptor cell R3,photoreceptor cell R4,ectopic,wing vein,wing & chaeta | somatic clone,mesothoracic tergum,mesothoracic tergum & chaeta | somatic clone,interommatidial bristle,supernumerary,eye,adult thorax,intestinal stem cell,trichome & abdominal tergite | somatic clone | cell non-autonomousë±Tub84B.PL,adult abdomen,crystal cell,tergite,adult cuticle,denticle belt,adult antennal segment,leg,adult head,vibrissae,pigment cell,wing blade,wing hair,eye photoreceptor cell,cell autonomous,progressive,autophagic vacuole | progressive | somatic clone,trichome,cuticle,wing & chaeta,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc,embryonic/larval brain,microtubuleen-e16E,denticle row 1,dorsal,posterior,crossvein" FBgn0019947 Psn Presenilin http://flybase.net/reports/FBgn0019947.html FBgn0042202 protein_coding_gene "0004175=endopeptidase activity, 0042803=protein homodimerization activity, 0004190=aspartic-type endopeptidase activity" "0007219=Notch signaling pathway, 0006816=calcium ion transport, 0042987=amyloid precursor protein catabolic process, 0007010=cytoskeleton organization, 0007220=Notch receptor processing, 0046331=lateral inhibition, 0050435=beta-amyloid metabolic process, 0002027=regulation of heart rate, 0048190=wing disc dorsal/ventral pattern formation, 0006509=membrane protein ectodomain proteolysis, 0016337=single organismal cell-cell adhesion, 0048812=neuron projection morphogenesis, 0015677=copper ion import, 0008593=regulation of Notch signaling pathway, 0043066=negative regulation of apoptotic process" "0009986=cell surface, 0030426=growth cone, 0005737=cytoplasm, 0043198=dendritic shaft, 0045121=membrane raft, 0070765=gamma-secretase complex, 0048471=perinuclear region of cytoplasm, 0005743=mitochondrial inner membrane, 0005887=integral component of plasma membrane, 0031594=neuromuscular junction, 0005634=nucleus, 0005765=lysosomal membrane, 0016324=apical plasma membrane, 0055037=recycling endosome, 0030018=Z disc, 0005770=late endosome, 0005938=cell cortex, 0030424=axon, 0035253=ciliary rootlet, 0043025=neuronal cell body" "presenilin, DPS, Dps, Dpresenilin, pres, DmPS, PSN, PS1, dPresenilin, unnamed, CG5868, l(3)77CDb, PS, dPsn, psn, pre-senelin, CG18803, DPsn, DrosPS" "IPR001108=Peptidase A22A, presenilin, IPR006639=Presenilin/signal peptide peptidase" CG18803 16-Dec-15 2015_12 "ENSDARG00000004870(psen1),ENSDARG00000015540(psen2)" WBGene00004769(sel-12) "ENSXETG00000001008(psen1),ENSXETG00000008548(psen2)" "ENSMUSG00000019969(Psen1),ENSMUSG00000010609(Psen2)" "ENSG00000143801(PSEN2),ENSG00000080815(PSEN1)" " embryonic stage | stage 16 , adult stage && oogenesis stage , larval stage | third instar , adult stage , embryonic stage | stage 14 , embryonic stage , larval stage " " central nervous system

, nurse cell

, eye-antennal disc | restricted

, oocyte

, ventral thoracic disc | posterior

" " larval stage , oogenesis stage , embryonic stage , pupal stage " " nurse cell

, follicle cell

" "visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,wild-type,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,hyperplasia,germline clone,cell death defective,cell autonomous,partially lethal - majority die,neuroanatomy defective,viable,fertile,chemical resistant,oxidative stress response defective" "third instar larva,wing disc,sensory mother cell,stage P4(i) prepupa,wing blade,adult external thorax,adult thoracic sensillum,eye,eye disc,eye disc & neuron,presumptive embryonic/larval central nervous system,germline clone,cytoskeleton & follicle cell | somatic clone,neurogenic region,embryonic neuroblast,epidermoblast,epidermis,wing,wing vein,wing margin bristle,proneural cluster,supernumerary,follicle cell,somatic clone,egg chamber,neuron & eye | supernumerary | somatic clone,distal,wing margin,morphogenetic furrow,ventral thoracic disc,type Ib terminal bouton,ommatidium,interommatidial bristle,pigment cell,lens,primary pigment cell,secondary pigment cell,tertiary pigment cell,ectopic,sensillum campaniformium of dorsal radius,sensillum campaniformium of proximal dorsal radius,wing vein L1,wing vein L3,crossvein,posterior,scutum & macrochaetac625,adult thorax & macrochaetac625,macrochaeta,scutum & macrochaeta19A,adult thorax & microchaeta19A,scutellar bristle,chaeta,mesothoracic tergum,scutellum,wing vein L5,head bristle,campaniform sensillum L3-1 of wing vein L3,campaniform sensillum L3-2 of wing vein L3,campaniform sensillum L3-3 of wing vein L3,sternopleural bristle,photoreceptor cell,tormogen cell" FBgn0003892 ptc patched http://flybase.net/reports/FBgn0003892.html "FBgn0013766, FBgn0015537, FBgn0064818" protein_coding_gene "0004888=transmembrane signaling receptor activity, 0008158=hedgehog receptor activity, 0005515=protein binding, 0030228=lipoprotein particle receptor activity" "0016311=dephosphorylation, 0048100=wing disc anterior/posterior pattern formation, 0006508=proteolysis, 0035225=determination of genital disc primordium, 0042981=regulation of apoptotic process, 0042306=regulation of protein import into nucleus, 0007476=imaginal disc-derived wing morphogenesis, 0007411=axon guidance, 0045879=negative regulation of smoothened signaling pathway, 0055088=lipid homeostasis, 0042078=germ-line stem cell division, 0007350=blastoderm segmentation, 0001746=Bolwig's organ morphogenesis, 0030707=ovarian follicle cell development, 0008406=gonad development, 0007455=eye-antennal disc morphogenesis, 0009952=anterior/posterior pattern specification, 2000274=regulation of epithelial cell migration, open tracheal system, 0007422=peripheral nervous system development, 0048477=oogenesis, 0007224=smoothened signaling pathway, 0007346=regulation of mitotic cell cycle, 0048103=somatic stem cell division, 0009880=embryonic pattern specification, 0048099=anterior/posterior lineage restriction, imaginal disc" "0045169=fusome, 0016021=integral component of membrane, 0030139=endocytic vesicle, 0005929=cilium, 0005886=plasma membrane, 0048471=perinuclear region of cytoplasm, 0005887=integral component of plasma membrane, 0005737=cytoplasm" "Conf, ptch, com4, rubberneck, Ptch, l(2)k02507, BcDNA:RH36596, compaction defects 4, Patched, patch, Ptc_Dm, Ptc, tufted, PTC, dPtc, rubr, Confused, CG2411, pat, tuf" "IPR003392=Patched, IPR000731=Sterol-sensing domain, IPR004766=Transmembrane receptor, patched" CG2411 16-Dec-15 2015_12 "ENSDARG00000055026(ptc1),ENSDARG00000016404(ptc2)" "WBGene00004208(ptc-1),WBGene00004210(ptc-3),WBGene00004209(ptc-2)" "ENSXETG00000014834(PTCH1),ENSXETG00000018892(PTCH2)" "ENSMUSG00000021466(Ptch1),ENSMUSG00000028681(Ptch2)" "ENSG00000185920(PTCH1),ENSG00000117425(PTCH2)" " embryonic stage , larval stage | third instar " " labrum

, Malpighian tubule

, analia

, neuroblast

, head

, embryonic/larval hindgut

, dorsal mesothoracic disc | anterior/posterior compartment boundary

,

segment polarity " " larval stage | third instar stage 2 , larval stage | third instar " " eye-antennal disc

restricted , dorsal mesothoracic disc | anterior/posterior compartment boundary

" "partially lethal - majority die,visible,viable,lethal,somatic clone,recessive,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,wild-type,increased cell death,mitotic cell cycle defective,cell lethalcell lethal,cell non-autonomous,lethal - all die before end of larval stage,some die during larval stage,planar polarity defective,cell migration defective,neuroanatomy defective,segment polarity phenotype,heat sensitive" "wing vein L3,wing vein L4,ectopic,somatic clone,wing margin bristle,ocellar triangle,fronto-orbital plate,frons,eye,head capsule & cuticle | ectopic,head bristle,ocellus,head capsule,antenna,eye-antennal disc,EL neuron,neuroblast NB7-3,neuroblast NB4-2,wing,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,photoreceptor cell,morphogenetic furrow,eye equator,gonad,scutellar bristle,adult head,cell non-autonomous,ommatidium,eye disc,antennal disc,wing margin,triple row,double row,head,anterior compartment,costal cell,wing vein,macrochaeta,wing disc,scutellum,1st posterior cell,anterior,sense organ,basal stalk,interfollicle cell,supernumerary,follicle stem cell,ovariole,follicle cell,oocyte,polar follicle cell,follicle cell & nucleus | somatic clone,border follicle cell,oocyte nucleus,germarium region 3,sex comb,eye photoreceptor cell,wing cell,ocellar bristle,imaginal disc,sensillum campaniformium of dorsal radius,female gonopod,dorsal,epiproct,scutellum & macrochaeta | somatic clone,embryonic/first instar larval cuticle,embryonic gnathal segment,RP2 motor neuron,Keilin's organ,embryonic epidermis,dorsal thick hair,denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,apodeme,embryonic somatic muscle,lateral,embryonic head,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,genital disc primordium,embryonic optic lobe,denticle row 1,denticle row 2,Bolwig organ,tergite,posterior vertical bristle,medial ocellus,egg chamber,germline clone,leg,sensory mother cell,sensillum campaniformium of dorsal radius Sc25,precursor,sensillum campaniformium of dorsal radius Sc4d,sensillum campaniformium of dorsal radius Sc12,marginal cell,embryonic/larval tracheal system,embryonic/larval ganglionic branch,wing basal cell 1,eye disc & morphogenetic furrow,photoreceptor cell & axon,denticle,germline cell,dorsal neurohemal organ,mesothoracic tarsal bristle longitudinal row 7,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 5.5,wing vein L2,microchaeta & head,embryonic segment,commissure,midline glial cell,ventral nerve cord,anterior commissure,posterior commissure,medial longitudinal fascicle,pCC neuron,wing sensillum,anterior crossvein,submarginal cell,embryonic/larval visceral branch,embryonic/larval dorsal branch,wing vein L5,posterior crossvein,pseudotrachea,heat sensitive,tergite & macrochaetahs.PB,wing blade" FBgn0014179 gcm glial cells missing http://flybase.net/reports/FBgn0014179.html FBgn0014259 protein_coding_gene "0001158=enhancer sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0010628=positive regulation of gene expression, 0042688=crystal cell differentiation, 0050764=regulation of phagocytosis, 0031290=retinal ganglion cell axon guidance, 0042387=plasmatocyte differentiation, 0030097=hemopoiesis, 0048813=dendrite morphogenesis, 0021782=glial cell development, 0045687=positive regulation of glial cell differentiation, 0060252=positive regulation of glial cell proliferation, 0007403=glial cell fate determination, 0010468=regulation of gene expression, 0030182=neuron differentiation, 0035169=lymph gland plasmatocyte differentiation, 0060857=establishment of glial blood-brain barrier, 0035164=embryonic plasmatocyte differentiation, 0006355=regulation of transcription, DNA-templated, 0045610=regulation of hemocyte differentiation, 0035289=posterior head segmentation, 0010001=glial cell differentiation, 0008283=cell proliferation, 0007516=hemocyte development, 0045893=positive regulation of transcription, DNA-templated, 0042063=gliogenesis, 0006952=defense response, 0035165=embryonic crystal cell differentiation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042690=negative regulation of crystal cell differentiation" 0005634=nucleus "ucc, glial cell missing, GCMa, GCM, glide/gcm, l(2)N7-4, glide glide2, N7-4, GCM1, Gcm, glia cells missing, upper class chordotonals, glial cell deficient, glial cells-missing, CG12245, glide" IPR003902=Transcription regulator GCM domain CG12245 16-Dec-15 2015_12 ENSMUSG00000021362(Gcm2) ENSG00000137270(GCM1) " embryonic stage | cellular blastoderm , embryonic stage | stage 11-13 , embryonic stage , embryonic stage | stage12 , embryonic stage | stage 9-11 , embryonic stage | stage 5-11 , embryonic stage | stage 10 , embryonic stage | stage 11-14 , embryonic stage | stage 11-17 , embryonic stage | stage 12-15 " " neuroblast NB6-4

, sense organ

, multidendritic sensory organ precursor cell

, tritocerebral neuroblast | subset

, head mesoderm

, medial-most cell body glial cell

, interface glial cell

, embryonic brain

, embryonic peripheral nervous system

, interface glial cell | precursor

, embryonic peripheral nervous system | restricted

, peripheral glial cell

, embryonic/larval hemocyte

, glial cell

, embryonic glial cell

, abdominal basiconical sensillum dbd

, neuroblast NB1-3

, lateral ectoderm

" " embryonic stage , embryonic stage | cellular blastoderm , embryonic stage | stage 11-17 , embryonic stage | stage 11-14 " " peripheral glial cell

, head mesoderm

, sense organ

, interface glial cell

, embryonic peripheral nervous system

, embryonic brain

, glial cell

" "viable,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,heat sensitive,melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,dominant,developmental rate defective,increased cell death,somatic clone,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,increased cell number,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "wing margin,sense organ,ectopic,sense organ & wing,glial cell,macrophage,embryonic/larval ganglionic branch,embryonic/larval glial cell,longitudinal connective,central nervous system,hemocyte,glioblast,embryonic neuroblast,nerve,embryonic/larval peritracheal cell,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,presumptive embryonic/larval central nervous system,lamina,somatic clone,eye photoreceptor cell stalk,ventral longitudinal muscle | embryonic stage,medulla neuropil glial cell,heat sensitive,melanotic mass,lamellocyte,plasmatocyte,mesothoracic tergum & macrochaeta | supernumerary | conditional ts,wing sensillum,embryonic/larval hemocyte,dMP2 neuron,pCC neuron,PNS exit glial cell,peripheral glial cell,intersegmental nerve,segmental nerve,embryonic/larval somatic muscle,embryonic/larval nervous system,dendrite,axon | embryonic stage,commissure,neuron,interface glial cell,metathoracic laterotergite & macrochaeta | supernumerary,scutum & macrochaeta | supernumerary,scutellum & macrochaeta | supernumerary,chaeta,supernumerary,macrochaeta,mesothoracic tergum & macrochaeta | supernumerary,fascicle,support cell of the dorsal bipolar dendritic cell,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,ventral abdominal cluster,ventral thoracic cluster,lch3 neuron,lch5 neuron,segmental nerve pioneer neuron,aCC neuron,embryonic/larval neuron,intermediate longitudinal fascicle,precursor,sensory neuron,neuropil associated CNS glial cell,ventral longitudinal muscle,wing & thecogen cell | somatic clone,wing & neuron | supernumerary | somatic clone,embryonic maxillary segment,embryonic mandibular segment,subperineurial glial cell,CNS glial cell,crystal cell,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial ligament cell & stage 16 embryo,lch5 ligament attachment cell,neuroblast NB6-4,neuroblast NB6-4 of thorax,neuroblast,mesothoracic tergum & macrochaeta | supernumerary | conditional tshs.PB,campaniform sensillum L3-3 of wing vein L3,embryonic/larval visceral muscle,ventral nerve cord,anterior commissure,posterior commissure,embryonic epidermis,dorsal,type II neuroblast,crystal cell primordium,bipolar dendrite neuron,outer photoreceptor cell,optic lobe,medulla cortex & glial cell | somatic clone,wing & sensillum campaniformium | supernumerary | somatic clone" FBgn0267615 CR45953 http://flybase.net/reports/FBgn0267615.html non_protein_coding_gene CR45953 16-Dec-15 2015_12 FBgn0001041 fs(3)HO5A female sterile (3) HO5A http://flybase.net/reports/FBgn0001041.html gene "fs(3)H05A, fs(3)f1, fs(3)f1[5A]" 16-Dec-15 2015_12 "female sterile,recessive" "ovary,oviduct,germarium,vitellarium,calyx of oviduct" FBgn0011817 nmo nemo http://flybase.net/reports/FBgn0011817.html "FBgn0014365, FBgn0019910, FBgn0023460, FBgn0044612, FBgn0046458, FBgn0062087" protein_coding_gene "0005524=ATP binding, 0004707=MAP kinase activity, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0016318=ommatidial rotation, 0007476=imaginal disc-derived wing morphogenesis, 0007474=imaginal disc-derived wing vein specification, 0008586=imaginal disc-derived wing vein morphogenesis, 0042332=gravitaxis, 0048749=compound eye development, 0046777=protein autophosphorylation, 0006468=protein phosphorylation, 0030178=negative regulation of Wnt signaling pathway, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0001736=establishment of planar polarity" 0005634=nucleus "Nemo-like kinase, NEMO, anon-WO0118547.332, CG7892, anon-WO0140519.256, anon-EST:Liang-2.43, Nemo, ORE-6, clone 2.43, anon-WO0172774.138, nemo, adk1, Nlk, dNEMO, anon-EST:Gibbs3, adirondack, NEMO/NLK, adk, Nmo, NLK" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site" CG7892 16-Dec-15 2015_12 ENSDARG00000028793(nlk2) WBGene00003048(lit-1) ENSXETG00000012503(NLK) ENSMUSG00000017376(Nlk) ENSG00000087095(NLK) " embryonic stage -- adult stage , larval stage | third instar " morphogenetic furrow

"lethal,planar polarity defective,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,viable,fertile,visible,behavior defective,dominant,cell polarity defective,recessive,gravitaxis defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,decreased cell size,partially lethal - majority die,germline clone,maternal effect,cell death defective,locomotor rhythm defective" "ommatidium,somatic clone,wing vein,ectopic,ommatidial precursor cluster,eye,wing,interommatidial bristle,secondary pigment cell,NMJ bouton,type I bouton,NMJ bouton | third instar larval stage,denticle belt,embryonic/first instar larval cuticle,embryonic head,dorsal closure embryo,wing blade,germline clone,maternal effect,denticle,embryonic segment,tertiary pigment cell,crossvein,mesothoracic tergum & macrochaeta,head bristle,wing vein L2,posterior crossvein,anterior,abdominal tergite & microchaeta69B,abdominal tergite & macrochaeta69B,scutum & macrochaetaap-md544,scutellar bristle,wing margin,wing cell,submarginal cell" DRSC11377 E -0.03788878 -1.322827467 -1.899991609 0.684221664 -0.053329763 0.889884637 FBgn0033421 CG1888 http://flybase.net/reports/FBgn0033421.html protein_coding_gene CG1888 16-Dec-15 2015_12 viable embryonic/larval hemocyte | third instar larval stage FBgn0013432 bcn92 bcn92 http://flybase.net/reports/FBgn0013432.html "FBgn0045295, FBgn0047082" protein_coding_gene "EG:87B1.6, BcDNA:RE57896, CG3717, NEST:bs15a04" IPR008011=Complex 1 LYR protein CG3717 16-Dec-15 2015_12 YER048W-A(ISD11) ENSXETG00000025591(LYRM4) ENSMUSG00000046573(Lyrm4) ENSG00000214113(LYRM4) "partially lethal - majority die,some die during pupal stage" FBgn0264855 AP-2ë± "Adaptor Protein complex 2, ë± subunit" http://flybase.net/reports/FBgn0264855.html "FBgn0065772, FBgn0263350, FBgn0015567, FBgn0010623, FBgn0260562" protein_coding_gene 0008565=protein transporter activity "0007269=neurotransmitter secretion, 0030100=regulation of endocytosis, 0008356=asymmetric cell division, 0022008=neurogenesis, 0008104=protein localization, 0045807=positive regulation of endocytosis, 0006901=vesicle coating, 0016183=synaptic vesicle coating, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0006897=endocytosis, 0048489=synaptic vesicle transport" "0005886=plasma membrane, 0008021=synaptic vesicle, 0030122=AP-2 adaptor complex, 0030135=coated vesicle" "CG4260, Alpha-adaptin, alpha-Adaptin, alpha-ada, AP-2alpha, D-alphaAda, alpha-Ada, l(2)06694, cg4260, AP-2, AP2, apl3, MENE(2L)-A, alpha, MENE (2L)-A, ada, lethal (2) SH0460, l(2)SH2 0460, CG31654, alpha-adaptin, D-Ada, alpha adaptin, dAP-2a, l(2)SH0460, Alpha-Adaptin, alphaAdaptin" "IPR009028=Coatomer/calthrin adaptor appendage, C-terminal subdomain, IPR008152=Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR013041=Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR017104=Adaptor protein complex AP-2, alpha subunit, IPR013038=Clathrin adaptor, alpha-adaptin, appendage, Ig-like subdomain, IPR011989=Armadillo-like helical, IPR003164=Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain, IPR015873=Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain, IPR016024=Armadillo-type fold, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal" CG4260 16-Dec-15 2015_12 ENSDARG00000054320(LOC558153) YBL037W(APL3) WBGene00000161(apa-2) "ENSXETG00000025765(ap2a2-2),ENSXETG00000009033(AP2A1)" "ENSMUSG00000002957(Ap2a2),ENSMUSG00000060279(Ap2a1)" "ENSG00000183020(AP2A2),ENSG00000196961(AP2A1)" " embryonic stage , embryonic stage && adult stage , embryonic stage&&adult stage , larval stage , embryonic stage && larval stage " " embryonic brain

, imaginal disc

, embryonic ventral nervous system

, garland cell

" " embryonic stage , embryonic stage | stage 8-12 , pupal stage , embryonic stage | stage >=8 , embryonic stage | early , larval stage , embryonic stage | stage >=14 , embryonic stage | stage >=13 , embryonic stage | late , embryonic stage | stage 8-11 " " proctodeum | primordium

, posterior midgut proper primordium

, sensory mother cell

, embryonic nervous system

, sensory mother cell

, ventral nerve cord

, bouton

, endoderm

, embryonic stomatogastric nervous system

, antenno-maxillary complex

, neuromuscular junction

, fat body primordium

, embryonic peripheral nervous system

, garland cell

, visceral mesoderm

, chordotonal organ

, embryonic/larval somatic muscle

, neuroblast

, head mesoderm

, cephalic furrow

, supraesophageal ganglion

, adult midgut precursor

, anterior midgut proper primordium

" DRSC00800 IE 1.505841149 1.315557142 0.293145832 1.752373102 0.954336378 0.627402719 FBgn0024277 trio trio http://flybase.net/reports/FBgn0024277.html "FBgn0015758, FBgn0028051, FBgn0028162, FBgn0035180, FBgn0035182, FBgn0046252" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005089=Rho guanyl-nucleotide exchange factor activity" "0045887=positive regulation of synaptic growth at neuromuscular junction, 0050770=regulation of axonogenesis, 0016319=mushroom body development, 0035025=positive regulation of Rho protein signal transduction, 0030036=actin cytoskeleton organization, 0048675=axon extension, 0007422=peripheral nervous system development, 0031532=actin cytoskeleton reorganization, 0007412=axon target recognition, 0071772=response to BMP, 0007417=central nervous system development, 0046331=lateral inhibition, 0007411=axon guidance, 0007480=imaginal disc-derived leg morphogenesis" "0031234=extrinsic component of cytoplasmic side of plasma membrane, 0030424=axon, 0030426=growth cone" "M89, 1372/03, Trio, 0959/14, 1386/06, 0368/10, UNC-73/Trio, l(3)S138606, l(3)036810, l(3)6D104, BEST:LD36950, l(3)S[1372/3], CG18214, CG9208, l(3)S137203, dTrio, l(3)S[1386/06], TRIO, l(3)S095914, l(3)S036810, DTrio, l(3)trio" "IPR000219=Dbl homology (DH) domain, IPR001331=Guanine-nucleotide dissociation stimulator, CDC24, conserved site, IPR001452=SH3 domain, IPR002017=Spectrin repeat, IPR028570=Triple functional domain protein, IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR018159=Spectrin/alpha-actinin, IPR001251=CRAL-TRIO lipid binding domain" CG18214 16-Dec-15 2015_12 "ENSDARG00000019426(si:dkey-158b13.2),ENSDARG00000004629(LOC100329539)" WBGene00006805(unc-73) "ENSMUSG00000022263(Trio),ENSMUSG00000061751(Kalrn)" "ENSG00000038382(TRIO),ENSG00000160145(KALRN)" " adult stage , larval stage | third instar , larval stage && pupal stage , larval stage && adult stage , embryonic stage , embryonic stage | stage 12-17 " " mushroom body

, lamina

, neuron

, calyx of mushroom body

, eye disc

, adult brain

, epidermis

, neuron

, longitudinal connective

, mushroom body gamma-lobe

, mushroom body alpha'-lobe

, mushroom body beta'-lobe

, ellipsoid body

, muscle attachment site

, commissure

" "lethal,recessive,neuroanatomy defective,somatic clone,viable,visible,partially lethal - majority live,some die during P-stage,partially lethal - majority die,locomotor behavior defective,sterile,wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage" "adult mushroom body,somatic clone,wing,vertical branch of mushroom body,medial branch of mushroom body,ellipsoid body,photoreceptor cell & axon,intersegmental nerve,longitudinal connective,abdominal segmental nerve,RP3 motor neuron,embryonic/larval neuromuscular junction,NMJ bouton,photoreceptor cell & axonGMR.PF,photoreceptor cell R7,photoreceptor cell & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,axon | somatic clone | third instar larval stage,embryonic somatic muscle,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,presumptive embryonic/larval central nervous system,embryonic/larval central nervous system,commissure,anterior commissure,posterior commissure,eye photoreceptor cell,embryonic central nervous system & axon,embryonic peripheral nervous system & axon,eye,photoreceptor cell,photoreceptor cell & eye discGMR.PF,ommatidium,medulla,chaeta,supernumerary,trichogen cell" FBgn0010434 cora coracle http://flybase.net/reports/FBgn0010434.html "FBgn0005646, FBgn0022032" protein_coding_gene "0008092=cytoskeletal protein binding, 0003779=actin binding, 0005198=structural molecule activity" "0007435=salivary gland morphogenesis, 0006612=protein targeting to membrane, 0061343=cell adhesion involved in heart morphogenesis, 0007527=adult somatic muscle development, 0048598=embryonic morphogenesis, 0019991=septate junction assembly, 0035321=maintenance of imaginal disc-derived wing hair orientation, 0003015=heart process, 0045216=cell-cell junction organization, 0060857=establishment of glial blood-brain barrier, 0035151=regulation of tube size, open tracheal system, 0008362=chitin-based embryonic cuticle biosynthetic process, 0007391=dorsal closure, 0007010=cytoskeleton organization, 0007163=establishment or maintenance of cell polarity" "0005856=cytoskeleton, 0005886=plasma membrane, 0045169=fusome, 0045170=spectrosome, 0005920=smooth septate junction, 0005918=septate junction" "Coracle, mdcds_14526, D4.1, Cora, CG11949, unnamed, cor, Cor, l(2)k08713, D4.1-Coracle, COR" "IPR019747=FERM conserved site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000299=FERM domain, IPR014847=FERM adjacent (FA), IPR029071=Ubiquitin-related domain, IPR008379=Band 4.1, C-terminal, IPR018979=FERM, N-terminal, IPR018980=FERM, C-terminal PH-like domain, IPR019748=FERM central domain" CG11949 16-Dec-15 2015_12 ENSDARG00000002255(zgc:92004) "ENSXETG00000012111(),ENSXETG00000004959(epb41l3),ENSXETG00000014407(epb41)" "ENSMUSG00000024044(Epb4.1l3),ENSMUSG00000019978(Epb4.1l2)" "ENSG00000082397(EPB41L3),ENSG00000079819(EPB41L2),ENSG00000159023(EPB41)" " larval stage | second instar , larval stage | first instar , embryonic stage | 8-20 hr , larval stage , embryonic stage | 4-20 hr " " embryonic stage | stage >=13 , embryonic stage | stage >=12 , adult stage && oogenesis stage | early , larval stage && pupal stage " " scolopidium

, abdominal 1--7 lateral pentascolopidial chordotonal organ lch5 | precursor

, epidermis

, terminal filament

, dorsal mesothoracic disc

, embryonic/larval salivary gland

, germarium cap cell

, embryonic/larval trachea

, eye-antennal disc

, follicle cell

, chordotonal organ

, embryonic/larval foregut

, embryonic/larval hindgut

" "lethal,recessive,neuroanatomy defective,neurophysiology defective,viable,fertile,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,cell polarity defective,cell lethal,partially,somatic clone,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,immune response defective" "embryonic/first instar larval cuticle,dorsal,embryonic/larval salivary gland,eye,anterior,interommatidial bristle,ommatidium,embryonic dorsal epidermis,eye equator,embryonic head,embryonic ganglionic branch & embryonic tracheole,dorsal trunk primordium,wing hair,dorsal closure embryo,presumptive embryonic salivary gland,presumptive embryonic/larval tracheal system,pleated septate junction,septate junction | embryonic stage,septate junction,denticle belt,ocellus,ocellar bristle,interocellar bristle,embryonic/larval tracheal system,indirect flight muscle,smooth septate junctionNP3084" FBgn0010316 dap dacapo http://flybase.net/reports/FBgn0010316.html "FBgn0010576, FBgn0015920" protein_coding_gene 0004861=cyclin-dependent protein serine/threonine kinase inhibitor activity "0045035=sensory organ precursor cell division, 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0007050=cell cycle arrest, 0007424=open tracheal system development, 0007294=germarium-derived oocyte fate determination, 0007423=sensory organ development, 0048477=oogenesis, 0045859=regulation of protein kinase activity, 0035308=negative regulation of protein dephosphorylation, 0007488=histoblast morphogenesis, 0045786=negative regulation of cell cycle, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0000278=mitotic cell cycle, 0000082=G1/S transition of mitotic cell cycle" "0005739=mitochondrion, 0005654=nucleoplasm, 0005634=nucleus" "l(2)04454, decapo, Decapo, p21/Dacapo, CDI4, p27, p27[Dap], p21[dacapo], chakra, p21/dacapo, Dacapo, P15, CIB1, Dacpao, Dacap0, Cyclin-dependent kinase interactor 4, p27cip/kip, CG1772, cdi4, Dacapo/p21, Dap, p21, DAP, E(Sev-CycE)2B, Dac, CDKN2B, dacapo/cyclin-dependent kinase interactor 4, Cdi4" IPR003175=Cyclin-dependent kinase inhibitor CG1772 16-Dec-15 2015_12 "WBGene00000516(cki-1),WBGene00000517(cki-2)" " embryonic stage | stage 6 , embryonic stage , embryonic stage | early , larval stage " " cephalic furrow

, ventral nerve cord | restricted

, ectoderm

, organism | 0-10% egg length

, morphogenetic furrow

, posterior midgut proper primordium

, embryonic central nervous system

, mesoderm

, amnioserosa

, eye-antennal disc

, ventral furrow

, epidermis

, morphogenetic furrow | posterior to

, supraesophageal ganglion

, peripheral nervous system

, anterior midgut proper primordium

" " embryonic stage | stage 6 , embryonic stage | early , embryonic stage " " amnioserosa

, pole cell

, yolk nucleus

, epidermis

, peripheral nervous system

, ventral nerve cord | restricted

, embryonic central nervous system

" "lethal,partially,recessive,partially lethal - majority die,mitotic cell cycle defective,neuroanatomy defective,visible,viable,somatic clone,decreased cell death,female sterile,size defective" "macrochaeta,embryonic/larval transverse connective,embryonic/larval dorsal trunk,interface glial cell,embryo,embryonic abdomen & glial cell | ectopic,embryonic epidermis,dorsocentral bristle,trichogen cell,tormogen cell,scutellar bristle,wing hair,wing margin,mesothoracic tergum,chaeta,eye,ommatidium,mitotic cell cycle | ectopic,external sensory organ precursor cell IIIb & S phase,PNS glial cell & S phase,oocyte,germline clone,karyosome,embryonic/larval optic lobe,lch1 neuron,ectopic,follicle cell & nucleus | somatic clone,mitotic cell cycle,eye disc,wing,posterior compartment,embryonic segment,wing cell,follicle stem cell,somatic clone,mitotic cell cycleunspecified,neuroblast NB6-4 of thorax,neuron & embryonic thorax-537.4,dorsal appendage,egg,chorion,G1 phase & external sensory organ precursor cell IIbneur-P72,G1 phase & external sensory organ precursor cell IIaneur-P72,embryonic pericardial cell,cardioblast,wing disc,histoblast,embryonic/larval epidermis,adult abdomen,eye disc posterior to the morphogenetic furrow" FBgn0015420 l(1)16Cb lethal (1) 16Cb http://flybase.net/reports/FBgn0015420.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0003984 vn vein http://flybase.net/reports/FBgn0003984.html "FBgn0001609, FBgn0002436, FBgn0010946, FBgn0011493" protein_coding_gene "0008201=heparin binding, 0005154=epidermal growth factor receptor binding" "0043066=negative regulation of apoptotic process, 0035310=notum cell fate specification, 0008284=positive regulation of cell proliferation, 0007482=haltere development, 0016203=muscle attachment, 0007422=peripheral nervous system development, 0007477=notum development, 0007267=cell-cell signaling, 0030031=cell projection assembly, 0008586=imaginal disc-derived wing vein morphogenesis, 0007474=imaginal disc-derived wing vein specification, 0007420=brain development, 0007298=border follicle cell migration, 0007173=epidermal growth factor receptor signaling pathway, 0045742=positive regulation of epidermal growth factor receptor signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0007494=midgut development, 0007479=leg disc proximal/distal pattern formation, 0008355=olfactory learning" "0005886=plasma membrane, 0005576=extracellular region" "Vein, l(3)10568, Vn, l(3)rF264, vein, l(3)vn10567, P1749, defective dorsal discs, l(3)ddd, CT29452, CG10491, l(3)L6A, Dm vein, ddd, Dm vn, l(3)10567, wvn" "IPR003598=Immunoglobulin subtype 2, IPR000742=EGF-like domain, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR013032=EGF-like, conserved site" CG10491 16-Dec-15 2015_12 ENSG00000120729(MYOT) " embryonic stage , embryonic stage | stage <=11 , larval stage&&pupal stage , embryonic stage | stage 10 , embryonic stage | stage >=11 , embryonic stage | blastoderm , pupal stage , larval stage , embryonic stage | stage 16 , embryonic stage | stage 11-12 , embryonic stage | stage 10-15 , embryonic stage | stage 11-14 " " ventral midline | restricted

, central nervous system

, amnioserosa

, scutum | presumptive

, tracheal pit

, peripheral nervous system | restricted

, Keilin's organ

, dorsal mesothoracic disc | restricted

, amnioserosa | precursor

, wing cell

, eye-antennal disc

, ventral thoracic disc

, visceral muscle

, dorsal metathoracic disc

, vMP2 neuron

, epidermis

, somatic muscle

, embryonic foregut

ventral & dorsal & anterior , embryonic central brain

subset , labral segment

, chordotonal organ

, labial segment

, maxillary lobe

, organism | striped & ventro-lateral

, stomodeum

, dMP2 neuron

" " embryonic stage | stage 11-14 , embryonic stage | stage 11-12 " " dMP2 neuron

, vMP2 neuron

" "lethal,recessive,decreased cell number,lethal - all die before end of P-stage,some die during pharate adult stage,learning defective,RU486 conditional,visible,viable,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,partially,some die during larval stage,male sterile,neuroanatomy defective,heat sensitive,partially lethal - majority live,homeotic,mitotic cell cycle defective" "lch5 ligament attachment cell,embryonic/larval midgut,gastric caecum,midgut constriction 1,midgut constriction 2,midgut constriction 3,ventral oblique muscle,ventral longitudinal muscle,dorsal oblique muscle,embryonic/larval somatic muscle,abdominal 2 dorsal acute muscle 1,precursor,abdominal 3 dorsal acute muscle 1,abdominal 4 dorsal acute muscle 1,abdominal 5 dorsal acute muscle 1,abdominal 6 dorsal acute muscle 1,abdominal 7 dorsal acute muscle 1,adult midgut precursor cell,midgut,wing vein L4,anterior crossvein,wing,border follicle cell & filopodiumslbo.2.6,border follicle cell,wing vein,ocellus,ocellar bristle,postvertical bristle,adult cuticle & head capsule | dorsal,wing disc,haltere disc,embryonic/larval brain,ventral nerve cord,wing vein L3,posterior crossvein,crossvein,embryonic central brain,dMP2 neuron,interface glial cell,longitudinal connective,lateral longitudinal fascicle,intermediate longitudinal fascicle,Keilin's organ,embryonic/first instar larval cuticle,ventral,Kolbchen,scutum,muscle attachment site,larva,sensory neuron & axon & embryo,chordotonal organ,anterior fascicle sensory neuron,posterior fascicle sensory neuron,imaginal disc,abdominal 2 lateral longitudinal muscle 1,abdominal 3 lateral longitudinal muscle 1,abdominal 4 lateral longitudinal muscle 1,abdominal 5 lateral longitudinal muscle 1,abdominal 6 lateral longitudinal muscle 1,abdominal 7 lateral longitudinal muscle 1,abdominal 2 ventral acute muscle 2,abdominal 3 ventral acute muscle 2,abdominal 4 ventral acute muscle 2,abdominal 5 ventral acute muscle 2,abdominal 6 ventral acute muscle 2,abdominal 7 ventral acute muscle 2,midline glial cell,ventral nerve cord commissure,ectopic,wing margin,somatic clone,eye,dorsal mesothoracic disc & peripodial epithelium | somatic cloneë±Tub84B.PL,dorsal mesothoracic disc & peripodial epithelium | somatic clone | cell non-autonomousë±Tub84B.PL,capitellum,wing margin bristle,intestinal stem cell,supernumerary,adult midgut precursor cell | late third instar larval stage" FBgn0015946 grim grim http://flybase.net/reports/FBgn0015946.html FBgn0064894 protein_coding_gene 0042803=protein homodimerization activity "0043068=positive regulation of programmed cell death, 0035193=larval central nervous system remodeling, 0043524=negative regulation of neuron apoptotic process, 0010623=developmental programmed cell death, 0035006=melanization defense response, 0045476=nurse cell apoptotic process, 0008340=determination of adult lifespan, 0097190=apoptotic signaling pathway, 2001272=positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis, 1901216=positive regulation of neuron death, 0008627=intrinsic apoptotic signaling pathway in response to osmotic stress, 0006915=apoptotic process, 0012501=programmed cell death, 0043065=positive regulation of apoptotic process" "0005739=mitochondrion, 0005737=cytoplasm" "Grim, grm, GRIM, gri, BcDNA:RE28551, CG4345" CG4345 16-Dec-15 2015_12 embryonic stage | stage >=11 ventral nerve cord | restricted

"decreased cell death,neuroanatomy defective,cell death defective,lethal,lethal - all die before end of pupal stage,some die during pupal stage,visible,size defective,increased cell death,dominant,partially,tarsal response defective,short lived,cell lethal,developmental rate defective,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,partially lethal - majority die,female semi-fertile,courtship behavior defective,male limited,large body,increased cell number,lethal - all die during larval stage,feeding behavior defective" "peptidergic neuron,ectopic,EW3 neuron,EW3 neuron | prepupal stage,eye,ommatidium,interommatidial bristle,eye disc,wing,mesothoracic tergum,peptidergic neuron | third instar larval stage,EW3 neuron | third instar larval stage,sensory neuron & axon & embryo,peripheral glial cell | embryonic stage,sensory neuron & axon & embryorepo,microchaeta,macrochaeta,embryonic/larval nervous system,embryonic/larval glial cell,segmental nerve pioneer neuron,aCC neuron,sensory neuron,ventral midline,ventral nerve cord,commissure,midline glial cell,embryonic/larval corpus allatum,embryonic/larval fat body | prepupal stage,photoreceptor cell R7 | prepupal stage,photoreceptor cell R8 | prepupal stage,optic lobe | prepupal stage,embryonic/larval salivary gland,fat body,mushroom body,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,gamma Kenyon cell,prothoracic gland innervating neuron PG-LP,embryonic/larval hemolymph | third instar larval stage,embryonic/larval tracheal system | larval stage,embryonic/larval spiracle | larval stage,glial cell,abdominal neuroblast" FBgn0023095 caps capricious http://flybase.net/reports/FBgn0023095.html "FBgn0010789, FBgn0011519, FBgn0064925" protein_coding_gene "0016477=cell migration, 0007155=cell adhesion, 0046331=lateral inhibition, 0007411=axon guidance, 0007476=imaginal disc-derived wing morphogenesis, 0007436=larval salivary gland morphogenesis, 0072499=photoreceptor cell axon guidance, 0035147=branch fusion, open tracheal system, 0007416=synapse assembly, 0008045=motor neuron axon guidance, 0007424=open tracheal system development, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" "0036194=muscle cell projection, 0016020=membrane, 0035230=cytoneme" "CAPS, BcDNA:LD07388, CT31495, l(3)rM632, l(3)02937, capricious, CG11282, Caps, Capricious" "IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal" CG11282 16-Dec-15 2015_12 "ENSDARG00000062400(LOC558051),ENSDARG00000059430,ENSDARG00000060115(lrrn1)" WBGene00022129(Y71F9B.8) "ENSXETG00000005147(LRRN1),ENSXETG00000024194()" "ENSMUSG00000036295(Lrrn3),ENSMUSG00000026443(Lrrn2),ENSMUSG00000034648(Lrrn1)" "ENSG00000173114(LRRN3),ENSG00000175928(LRRN1),ENSG00000170382(LRRN2)" embryonic stage " abdominal dorsal acute muscle 1

, abdominal dorsal oblique muscle 2

, RP5 neuron

, abdominal ventral oblique muscle 6

, RP2 neuron

, abdominal ventral oblique muscle 5

, abdominal ventral oblique muscle 4

, abdominal dorsal oblique muscle 1

, abdominal ventral longitudinal muscle 1

, aCC neuron

, abdominal ventral oblique muscle 3

, U neuron

, abdominal dorsal acute muscle 2

, abdominal ventral oblique muscle 1

" " larval stage | third instar , embryonic stage , larval stage | first instar " " dorsal mesothoracic disc | dorsal comparment & lateral

, neuron

, synapse

" "lethal,recessive,neuroanatomy defective,somatic clone,viable,fertile,visible" "embryonic/larval salivary gland,photoreceptor cell R8,somatic clone,macrochaeta,A1-7 ventral motor neuron,axon,dorsal trunk primordium,motor neuron,motor neuron | third instar larval stage,dendriteMz19,projection neuron,abdominal anterior fascicle & synapse,intersegmental nerve branch ISNb of A1-7,eye photoreceptor cell,motor neuron | embryonic stage,air sac primordium | third instar larval stage,photoreceptor cell R7,wing disc,dorsal/ventral compartment boundary,ventral compartment,abdominal ventral longitudinal muscle 2 & synapseG14,synapse | ectopicG14,abdominal anterior fascicle & synapseG14,abdominal ventral longitudinal muscle 2 & synapsel(3)H94-H94,synapse | ectopicl(3)H94-H94,abdominal anterior fascicle & synapsel(3)H94-H94,transverse nerve,lateral trunk primordium,antennal lobe,dendrite | somatic cloneunspecified,antennal lobe projection neuron,adult antennal lobe projection neuron DL1 adPN,dendrite | somatic cloneGH146,leg,ventral thoracic disc,antennal lobe projection neuron lPN,dendrite | somatic clone,adult antennal lobe projection neuron DM1 lPN,adult antennal lobe projection neuron VA4 lPN,adult antennal lobe projection neuron VC2 lPN,pretarsus,adult antennal lobe projection neuron VC1 lPN,chaeta,trichogen cell,supernumerary" FBgn0010397 LamC Lamin C http://flybase.net/reports/FBgn0010397.html FBgn0010037 protein_coding_gene 0005198=structural molecule activity "0031081=nuclear pore distribution, 0006325=chromatin organization, 0035989=tendon development, 0030833=regulation of actin filament polymerization, 0006342=chromatin silencing, 0007084=mitotic nuclear envelope reassembly, 0060415=muscle tissue morphogenesis" "0005638=lamin filament, 0005637=nuclear inner membrane, 0005635=nuclear envelope, 0034399=nuclear periphery, 0070732=spindle envelope, 0005652=nuclear lamina" "pG-IF, G-IF, LAMC, G intermediate filament, LaminC, lamin C, CG10119, lamin DmC, DmC, lamin A, laminC, lamC" "IPR001322=Lamin Tail Domain, IPR001664=Intermediate filament protein, IPR027696=Lamin" CG10119 16-Dec-15 2015_12 "ENSDARG00000009933(lmnb2),ENSDARG00000044299(lmnb1),ENSDARG00000013415(lmna)" WBGene00003052(lmn-1) "ENSXETG00000001795(lmnb2),ENSXETG00000005162(lmnb1),ENSXETG00000024161(LMNA),ENSXETG00000015792(lmna)" "ENSMUSG00000024590(Lmnb1),ENSMUSG00000062075(Lmnb2),ENSMUSG00000028063(Lmna)" "ENSG00000113368(LMNB1),ENSG00000176619(LMNB2),ENSG00000160789(LMNA)" " embryonic stage | >=12 hr , embryonic stage | stage 13 , embryonic stage | stage 12 , larval stage--adult stage " " embryonic/larval dorsal trunk

, oenocyte

, embryonic/larval foregut

, embryonic/larval hindgut

" " embryonic stage | >=12-15 hr , embryonic stage | stage 15 , embryonic stage | stage 12 , larval stage , embryonic stage | stage 16 , embryonic stage | stage 12 | late , larval stage--adult stage , adult stage " " epidermis

, embryonic/larval foregut

, embryonic/larval dorsal trunk

, posterior spiracle primordium

, exit glial cell

, inclusive hindgut primordium

, oenocyte

, dorsal prothoracic pharyngeal muscle

, interfollicle cell

, visceral mesoderm

, germarium cap cell

" "lethal - all die before end of P-stage,some die during P-stage,viable,partially lethal - majority die,locomotor behavior defective,lethal,lethal - all die before end of first instar larval stage,increased cell death,partially lethal - majority live,visible,temperature conditional,recessive,heat sensitive,melanotic mass phenotype,lethal - all die before end of prepupal stage,some die during prepupal stage,some die during third instar larval stage,suppressor of variegation,dominant,developmental rate defective,body color defective,some die during pupal stage" "tendon cell,leg,pupa,nucleusUbx-lac1-Gal4,longitudinal muscle | first instar larval stage,indirect flight muscle,nucleusptc-559.1,anterior-posterior boundary of the wing disc | third instar larval stage,wing blade,scutellum,thorax,mesothoracic bristle,wing vein,somatic muscle | P-stage,tendon cell | larval stage,tendon cell | P-stage,embryonic/larval salivary gland,melanotic mass,heat sensitive,larval salivary gland & embryo & nucleus | conditional ts,imaginal disc,nuclear inner membrane | larval stage,nuclear outer membrane | larval stage,nuclear envelope | larval stage,nuclear pore | larval stage,nucleus | larval stage,mesothoracic tergum,nucleusC57,embryonic/larval somatic muscle,metathoracic femur,metathoracic tibia,metathoracic tarsal segment,ventral thoracic disc,metathoracic metatarsus" FBgn0016917 Stat92E Signal-transducer and activator of transcription protein at 92E http://flybase.net/reports/FBgn0016917.html "FBgn0010885, FBgn0011396, FBgn0015512" protein_coding_gene "0005515=protein binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0004871=signal transducer activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0035171=lamellocyte differentiation, 0007165=signal transduction, 0007442=hindgut morphogenesis, 0007476=imaginal disc-derived wing morphogenesis, 0043697=cell dedifferentiation, 0035167=larval lymph gland hemopoiesis, 0007298=border follicle cell migration, 0071481=cellular response to X-ray, 0035172=hemocyte proliferation, 0007379=segment specification, 0030097=hemopoiesis, 0046425=regulation of JAK-STAT cascade, 0017145=stem cell division, 0007259=JAK-STAT cascade, 0007616=long-term memory, 0030713=ovarian follicle cell stalk formation, 0007399=nervous system development, 0007350=blastoderm segmentation, 0030718=germ-line stem cell maintenance, 0042078=germ-line stem cell division, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0071222=cellular response to lipopolysaccharide, 0008284=positive regulation of cell proliferation, 0008348=negative regulation of antimicrobial humoral response, 0007526=larval somatic muscle development, 0007424=open tracheal system development, 0007425=epithelial cell fate determination, open tracheal system, 0048103=somatic stem cell division, 0048477=oogenesis, 0006952=defense response, 0019827=stem cell maintenance, 0030178=negative regulation of Wnt signaling pathway, 0002230=positive regulation of defense response to virus by host, 0006959=humoral immune response, 0035019=somatic stem cell maintenance, 0007538=primary sex determination, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0007455=eye-antennal disc morphogenesis, 0007530=sex determination" "0005634=nucleus, 0005737=cytoplasm" "mrl stat92E, pSTAT, marelle, CG4257, DmSTAT, Dstat, STAT 92E, stat92, D-Stat, stat92E, dSTAT92E/marelle, STAT92E, dstat, STAT92e, DRODSRC, Stat92e, stat92e, Dstat 92E, dSTAT92E, DSTAT, mrl, stat, d-STAT, D-stat, dSTAT, signal transducer and activator of transcription, Signal-transducer and activator of transcription protein, l(3)06346, STAT, DSRC, SD-stat, stat[92E], Stat1alpha-like, D-stat/stat92E, signal transducers and activator of transcription, Dstat92E, Stat92, mrL, D-STAT, l(3)j6C8, Marelle, Stat" "IPR008967=p53-like transcription factor, DNA-binding, IPR001217=Transcription factor STAT, IPR011992=EF-hand domain pair, IPR015988=STAT transcription factor, coiled coil, IPR000980=SH2 domain, IPR013800=STAT transcription factor, all-alpha domain, IPR013801=STAT transcription factor, DNA-binding, IPR012345=STAT transcription factor, DNA-binding, subdomain, IPR013799=STAT transcription factor, protein interaction" CG4257 16-Dec-15 2015_12 "ENSDARG00000019392(stat5.1),ENSDARG00000055588(stat5.2),ENSDARG00000015902(stat6)" WBGene00013111(sta-1) ENSXETG00000000836() "ENSMUSG00000020919(Stat5b),ENSMUSG00000004043(Stat5a),ENSMUSG00000002147(Stat6)" "ENSG00000173757(STAT5B),ENSG00000126561(STAT5A),ENSG00000166888(STAT6)" " embryonic stage | 1 hr , embryonic stage | early , embryonic stage | stage 15 , embryonic stage | extended germ band , embryonic stage -- adult stage , embryonic stage | 1-3 hr " "

ubiquitous , embryonic/larval foregut

, gonad | precursor

, embryonic/larval hindgut

, organism | segment polarity

, mesoderm

,

pair rule " oogenesis stage | stage S5-7 " nurse follicle cell

, centripetally migrating follicle cell

, border follicle cell

, polar follicle cell

" "small body,lethal,heat sensitive,memory defective,RU486 conditional,visible,viable,fertile,recessive,female sterile,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,maternal effect,rescuable maternal effect,wild-type,somatic clone,partially,germline clone,melanotic mass phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,planar polarity defective,dominant,pair rule phenotype,hyperplasia,increased cell death,conditional,stress response defective,partially lethal - majority die" "embryonic/larval somatic muscle,germline clone,wing,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic head,wing vein,ectopic,eye,somatic clone,antenna,follicle cell,polar follicle cell,oocyte,egg chamber,interfollicle cell,anterior,cell autonomous,male germline stem cell,germarium,cell non-autonomous,ovarian basement membrane,ovarian sheath cell,spectrosome | cell non-autonomous | somatic clone,cyst progenitor cell,male,spermatogonium,heat sensitive,spermatocyte,cyst cell,tracheal pit,border follicle cell,dorsal appendage,embryonic/larval anterior spiracle,spermathecum,supernumerary,leg,adult cuticle,germline stem cell,escort cell,escort stem cell,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,mesothoracic ventral denticle belt,non-rescuable maternal effect,presumptive embryonic/larval tracheal system,embryonic/larval proventriculus,embryonic hindgut,nurse follicle cell,pole cell,maternal effect,gonad,telson,segment,ovariole,embryonic/first instar larval cuticle,mesothoracic segment,abdominal segment 5,abdominal segment 8,filzkorper,embryonic/larval posterior spiracle,embryonic segment,embryonic/larval tracheal system,tracheal system,hindgut,hindgut & nucleus,central nervous system,commissure,longitudinal connective,peripheral nervous system,axon,denticle belt,rescuable maternal effect,germline cell,ectoderm,melanotic mass,larval optic anlage,embryonic abdominal segment,ommatidium,adult segment,trachea,epidermis,posterior compartment,embryonic/larval lymph gland,plasmatocyte,wing disc,conditional,cuticle & adult external head | somatic clone,head,eye disc,morphogenetic furrow,imaginal disc,dorsal prothorax,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,posterior spiracle primordium,tracheal branch primordium,mouth hooks,trichogen cell,mesothoracic tergum,midgut" DRSC16870 IE 0.899886427 2.078730627 -0.835424245 1.885027711 1.0967906 1.182478138 FBgn0020306 dom domino http://flybase.net/reports/FBgn0020306.html "FBgn0022058, FBgn0024590, FBgn0034621, FBgn0046413" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0008094=DNA-dependent ATPase activity, 0004386=helicase activity" "0022008=neurogenesis, 0035222=wing disc pattern formation, 0048813=dendrite morphogenesis, 0010629=negative regulation of gene expression, 0030097=hemopoiesis, 0045747=positive regulation of Notch signaling pathway, 0048477=oogenesis, 2000637=positive regulation of gene silencing by miRNA, 0070983=dendrite guidance, 0036098=male germ-line stem cell maintenance, 0035207=negative regulation of hemocyte proliferation, 0016573=histone acetylation, 0016458=gene silencing, 0008283=cell proliferation, 0002165=instar larval or pupal development, 0043486=histone exchange, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0035019=somatic stem cell maintenance, 0006325=chromatin organization" "0005634=nucleus, 0000123=histone acetyltransferase complex, 0035267=NuA4 histone acetyltransferase complex" "Domino-A, DOM, l(2)k02704, 27/4, DomA, Dom, DOM-A, domino DNA dependent ATPase, l(2)k08108, anon-WO0172774.190, p400, Domino, l(2)81/8, CG9696" "IPR017877=Myb-like domain, IPR000330=SNF2-related, N-terminal domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014012=Helicase/SANT-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG9696 16-Dec-15 2015_12 WBGene00007027(ssl-1) ENSXETG00000002041() ENSMUSG00000029505(Ep400) ENSG00000183495(EP400) "visible,neuroanatomy defective,viable,fertile,lethal,recessive,cell lethalcell lethal,somatic clone,female sterile,germline clone,immune response defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,male fertile,suppressor of variegation,dominant,partially lethal - majority live,maternal effect,lethal - all die before end of larval stage,some die during larval stage,decreased cell number" "wing margin,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,embryonic/larval lymph gland,hemocyte,imaginal disc,prohemocyte,imaginal ring,midgut imaginal island,embryonic/larval hemocyte,plasmatocyte,follicle stem cell,somatic clone,neuroblast,wing,anterior crossvein,ocellus,head bristle,mesothoracic tergum,tarsal segment,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,adult antennal lobe projection neuron DL1 adPN" DRSC04558 IE -1.426581268 -3.400750336 -0.155421592 -2.794748799 -0.400066297 -0.097519241 FBgn0003130 Poxn Pox neuro http://flybase.net/reports/FBgn0003130.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0008343=adult feeding behavior, 0048800=antennal morphogenesis, 0007423=sensory organ development, 0009415=response to water, 0008049=male courtship behavior, 0007476=imaginal disc-derived wing morphogenesis, 0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0007480=imaginal disc-derived leg morphogenesis" 0005634=nucleus "pox-neural, P4, Pox-n, Paired box neural, poxn, pox-neuro, CG8246, Paired box-neuro, pox-n, pox neuro, neuro, Pox-neuro" "IPR001523=Paired domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR009057=Homeodomain-like" CG8246 16-Dec-15 2015_12 embryonic stage " embryonic peripheral nervous system | restricted

, central nervous system | restricted

" " embryonic stage , prepupal stage | stage P1 , larval stage | third instar , embryonic stage | mid , embryonic stage | stage 11-13 " " Kolbchen | lateral metathoracic segment

, embryonic peripheral nervous system | restricted

, embryonic peripheral nervous system | segmentally repeated pattern

, organism

, central nervous system | restricted

, wing margin bristle | precursor | restricted

, ganglion mother cell

, central nervous system | segmentally repeated

, neuroblast

, Kolbchen | lateral mesothoracic segment

" "courtship behavior defective,male,lethal,recessive,visible,feeding behavior defective,viable,male sterile,mating defective,flight defective,taste perception defective,proboscis extension reflex defective" "wing vein L3,wing vein,wing vein L3 & macrochaeta,macrochaeta,ectopic,mechanosensory sensory organ & tibia & adult,mechanosensory sensory organ & tibia & neuron & adult,chemosensory sensory organ,mechanosensory sensory organ,chordotonal organ,external sensory organ,eye,Kolbchen,ommatidium,cone cell,dorsal triple row,chemosensory ventral triple row bristle,mesothoracic leg sensillum & tibia,mesothoracic leg taste bristle,metathoracic leg taste bristle,prothoracic leg taste bristle,labellar taste bristle,mechanosensory chaeta,penis,posterior lobe,clasper,wing hinge,adult brain,taste bristle,prothoracic ventral Kolbchen vbd,mesothoracic lateral Kolbchen lbd,mesothoracic ventral Kolbchen vbd,metathoracic lateral Kolbchen lbd,metathoracic ventral Kolbchen vbd,larval thoracic segment & sensillum campaniformium | ectopic,abdominal dorsal sensillum trichodeum dh1,larval abdominal segment & sensillum campaniformium | ectopic,larval abdominal segment & sensillum trichodeum | ectopic,mesothoracic les3 neuron,metathoracic les3 neuron,mesothoracic v'es3 neuron,metathoracic v'es3 neuron,des2 neuron,abdominal 1 v'es2 neuron,abdominal 2 v'es2 neuron,abdominal 3 v'es2 neuron,abdominal 4 v'es2 neuron,abdominal 5 v'es2 neuron,abdominal 6 v'es2 neuron,abdominal 7 v'es2 neuron,sensillum trichodeum,sensillum campaniformium,mesothoracic metatarsus,mesothoracic tarsal segment 2,mesothoracic tarsal segment 3,mesothoracic tarsal segment 4,mesothoracic tarsal segment 5,mesothoracic tarsal segment & joint,basal cylinder,arista,wing hinge & wing vein,wing hinge & wing vein L5,sensory mother cell,adult head,antenna" FBgn0085351 inaF-A inaF-A http://flybase.net/reports/FBgn0085351.html FBgn0023077 protein_coding_gene 0016247=channel regulator activity 0042391=regulation of membrane potential 0016020=membrane "CG34322, InaF, Dm_X:58729, inaF, INAF" "IPR029162=TRP-interacting helix, InaF motif" CG34322 16-Dec-15 2015_12 FBgn0264501 CR43900 http://flybase.net/reports/FBgn0264501.html non_protein_coding_gene CR43900 16-Dec-15 2015_12 FBgn0036078 Or67c Odorant receptor 67c http://flybase.net/reports/FBgn0036078.html protein_coding_gene "0005549=odorant binding, 0004984=olfactory receptor activity" "0050911=detection of chemical stimulus involved in sensory perception of smell, 0007608=sensory perception of smell" "0016021=integral component of membrane, 0032590=dendrite membrane" "DmOR67C, DOR77, 67c, 67D.1, CG14156" "IPR004117=Olfactory receptor, Drosophila" CG14156 16-Dec-15 2015_12 viable FBgn0003317 sax saxophone http://flybase.net/reports/FBgn0003317.html protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0046872=metal ion binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0005025=transforming growth factor beta receptor activity, type I, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0007476=imaginal disc-derived wing morphogenesis, 0007015=actin filament organization, 0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0007179=transforming growth factor beta receptor signaling pathway, 0045824=negative regulation of innate immune response, 0035222=wing disc pattern formation, 0008358=maternal determination of anterior/posterior axis, embryo, 0042078=germ-line stem cell division, 0007448=anterior/posterior pattern specification, imaginal disc, 0030718=germ-line stem cell maintenance, 0007304=chorion-containing eggshell formation, 0001745=compound eye morphogenesis, 0030707=ovarian follicle cell development, 0050829=defense response to Gram-negative bacterium, 0009953=dorsal/ventral pattern formation, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0008101=decapentaplegic signaling pathway, 0030509=BMP signaling pathway, 0007300=ovarian nurse cell to oocyte transport, 0048477=oogenesis, 0030514=negative regulation of BMP signaling pathway, 0006468=protein phosphorylation" "0005886=plasma membrane, 0005887=integral component of plasma membrane, 0043235=receptor complex" "STK-B, SAX, Saxophone, Sax, Sa, CG1891, Bkr43E, Brk43E" "IPR003605=GS domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR017194=Transforming growth factor-beta receptor, type II, IPR000472=Activin types I and II receptor domain, IPR000333=Ser/Thr protein kinase, TGFB receptor, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG1891 16-Dec-15 2015_12 ENSDARG00000014986(acvr1l) WBGene00004860(sma-6) ENSXETG00000010380(TEgg065o02.1) "ENSMUSG00000026836(Acvr1),ENSMUSG00000000530(Acvrl1)" "ENSG00000115170(ACVR1),ENSG00000139567(ACVRL1)" " embryonic stage -- adult stage , embryonic stage "

ubiquitous "viable,lethal,developmental rate defective,size defective,partially lethal - majority die,maternal effect,visible,dominant,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,wild-type,female sterile,neurophysiology defective,somatic clone,neuroanatomy defective,circadian rhythm defective" "imaginal disc,brain,trachea,germarium,female germline stem cell,amnioserosa,maternal effect,midgut constriction 2,anterior crossvein,eye,ommatidium,wing,wing vein,ectopic,egg,ovary,egg chamber,extended germ band embryo,cephalic furrow,embryonic head,filzkorper,abdominal segment 7,abdominal segment 8,embryonic/larval epidermis,dorsal,embryonic/larval midgut,embryonic/first instar larval cuticle,amnioproctodeal invagination,dorsal appendage,germline clone,wing vein L4,somatic clone,2nd posterior cell,dil cell,wing basal cell 2,fat body,neuromuscular junctionsax-H9),bouton,neuromuscular junctioncn7969),triple row,distal costal vein,dorsal double row,ventral double row,male germline stem cell,cell non-autonomous,trichome of the posterior wing margin,ovariole,synapse,t-bar,embryonic/larval dorsal branch,wing disc,wing vein L5,posterior crossvein,wing vein L2,dorsal triple row,proximal,medial triple row,ventral triple row,wing blade,posterior,wing cell,embryonic/larval tracheal system,trichogen cell,supernumerary" DRSC26844 K 0.401438369 0.01057449 0.394041202 0.198949049 -1.515195925 -1.309782523 FBgn0003651 svp seven up http://flybase.net/reports/FBgn0003651.html "FBgn0011337, FBgn0011492, FBgn0011510, FBgn0038010, FBgn0063263" protein_coding_gene "0004872=receptor activity, 0046982=protein heterodimerization activity, 0008270=zinc ion binding, 0042803=protein homodimerization activity, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0005515=protein binding, 0003707=steroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" "0006355=regulation of transcription, DNA-templated, 0007464=R3/R4 cell fate commitment, 0061331=epithelial cell proliferation involved in Malpighian tubule morphogenesis, 0007507=heart development, 0021782=glial cell development, 0046530=photoreceptor cell differentiation, 0007417=central nervous system development, 0001700=embryonic development via the syncytial blastoderm, 0042331=phototaxis, 0007465=R7 cell fate commitment, 0007510=cardioblast cell fate determination, 0043401=steroid hormone mediated signaling pathway, 0048749=compound eye development, 0007419=ventral cord development, 0007503=fat body development, 0014019=neuroblast development, 0007270=neuron-neuron synaptic transmission, 0007462=R1/R6 cell fate commitment, 0001752=compound eye photoreceptor fate commitment" "0005634=nucleus, 0005737=cytoplasm" "sevenup, 0114/20, l(3)rA028, Sevenup, complementation group 7, 0005/12, l(3)87Bd, CG11502, SVP1, don, ck16, NR2F3, l(3)07842, SEVEN-UP, CG18158, BcDNA:GH08189, 0861/07, 0106/18, SVP, down-and-out, Seven-up, Svp, SVP-1, 0351/01, Seven Up, 0042/01, l(3)rL069, seven-up, l(3)ck16, l(3)j2E2, Seven up, 0598/01" "IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR003068=Transcription factor COUP, IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR001628=Zinc finger, nuclear hormone receptor-type" CG11502 16-Dec-15 2015_12 " larval stage , embryonic stage | stage >=11 , embryonic stage | stage >=10 " " photoreceptor cell R4 | precursor

, morphogenetic furrow | posterior to

, Malpighian tubule tip cell

, Malpighian tubule | restricted

, photoreceptor cell R6 | precursor

, photoreceptor cell R3 | precursor

, photoreceptor cell R1 | precursor

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,planar polarity defective,somatic clone,visible,heat sensitive,uncoordinated,dominant,neuroanatomy defective,neurophysiology defective,phototaxis defective,viable,fertile,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal - all die during larval stage" "ommatidium,somatic clone,photoreceptor cell R1,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R6,precursor,macrochaeta,embryonic/larval oenocyte,photoreceptor cell R7,cone cell,eye,eye photoreceptor cell,heat sensitive,embryonic/larval ostia,U1 neuron,supernumerary,U4 neuron,U5 neuron,EW1 neuron,GW neuron,EW2 neuron,EW3 neuron,Malpighian tubule,outer photoreceptor cell,inner photoreceptor cell,ectopic,6-4Ic,6-4Ii,neuroblast NB6-4 of thorax,photoreceptor cell R2 & axon,photoreceptor cell R5 & axon,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,FMRFamide SE2 neuron,mystery cell,photoreceptor cell R8,photoreceptor cell & axon | somatic clone,lamina,medulla,dorsal closure embryo,U neuron,EW neuron,embryonic/larval optic stalk surface glial cell | third instar larval stage" DRSC17075 I 0.793767781 1.641326499 0.745384682 0.867669482 -0.465455488 0.021712991 FBgn0002962 nos nanos http://flybase.net/reports/FBgn0002962.html "FBgn0010916, FBgn0011347, FBgn0011364, FBgn0026836" protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding, 0003723=RNA binding" "0008595=anterior/posterior axis specification, embryo, 0016321=female meiosis chromosome segregation, 0048134=germ-line cyst formation, 0008354=germ cell migration, 0042078=germ-line stem cell division, 0017148=negative regulation of translation, 0030718=germ-line stem cell maintenance, 0045892=negative regulation of transcription, DNA-templated, 0006378=mRNA polyadenylation, 0007314=oocyte anterior/posterior axis specification, 0001709=cell fate determination, 0007280=pole cell migration, 0048813=dendrite morphogenesis, 0048477=oogenesis, 0035282=segmentation, 0007281=germ cell development, 0007283=spermatogenesis, 0043066=negative regulation of apoptotic process" 0045495=pole plasm "l(3)07117, DRONANOS, Nos, NOS, nNOS, Dronanos, nanos, l(3)j4B6, l(3)j3B6, Nanos, CG5637, NANOS" "IPR001878=Zinc finger, CCHC-type, IPR008705=Nanos/Xcat2, IPR024161=Zinc finger, nanos-type" CG5637 16-Dec-15 2015_12 " embryonic stage | 0-8 hr , adult stage | female , embryonic stage | stage 3-9 , embryonic stage | early , embryonic stage | stage 2 , embryonic stage | stage 1-2 , oogenesis stage , embryonic stage " " stage S4 oocyte && stage S5 oocyte && stage S6 oocyte

, stage S11 oocyte | posterior && stage S12 oocyte | posterior && stage S13 oocyte | posterior && stage S14 oocyte | posterior , stage S8 oocyte | anterior && stage S9 oocyte | anterior , pole cell

, pole plasm

, pole plasm

{ 0 pumMsc } , organism | 0-10% egg length

, organism | posterior

, pole plasm

{ 0 pumFC8 } ,

posterior ,

0-2% egg length{ - osk*, nosbcd.3UTR } ,

anterior " " embryonic stage | early , adult stage && oogenesis stage " "organism | posterior & gradient

, germline cyst &&of germarium region 2

, posterior | gradient

{ 0 pumFC8 } ,

gradient{ $ osk* } , cystoblast

,

gradient , female germline stem cell

, posterior | gradient

{ 0 pumMsc } " "neuroanatomy defective,viable,fertile,lethal,recessive,female sterile,increased cell death,maternal effect,meiotic cell cycle defective,dominant,partially lethal - majority die,some die during embryonic stage,wild-type,lethal - all die before end of embryonic stage,partially lethal - majority live,visible,somatic clone,partially,female fertile,lethal - all die before end of pupal stage,some die during pupal stage" "mushroom body & axon7B,Kenyon cell,mushroom body & axoney-OK107,abdominal segment,pole cell,maternal effect,germline cell,dorsal closure embryo,embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,abdomen,extended germ band embryo,embryonic/first instar larval cuticle,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,filzkorper,embryonic head,embryonic thorax,anterior,embryo,ectopic,posterior,ovariole,egg chamber,germline cyst,class IV dendritic arborizing neuron,female germline stem cell,somatic clone,telson,germarium,female germline stem cell & plasma membrane,cystoblast & plasma membrane,cystocyte & plasma membrane,mitochondrion,testis,ovary,germline stem cell,embryonic epidermis,cephalopharyngeal skeleton,eye,dorsal bridge,vertical bridge,gonad,cystocyte,spectrosome,fusome,egg,dendritic arborising neuron & dendrite | somatic clone,dendritic arborising neuron & dendritic tree8-123,adult cuticle,wing,ommatidium,dendritic arborising neuron & dendritic tree109(2)80,dendritic arborising neuron & dendritic tree477,embryonic thoracic segment" FBgn0035776 CG8564 http://flybase.net/reports/FBgn0035776.html protein_coding_gene "0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" "0022008=neurogenesis, 0006508=proteolysis" "IPR000834=Peptidase M14, carboxypeptidase A" CG8564 16-Dec-15 2015_12 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0263106 DnaJ-1 DnaJ-like-1 http://flybase.net/reports/FBgn0263106.html "FBgn0015657, FBgn0044712, FBgn0046460, FBgn0044052" protein_coding_gene 0051082=unfolded protein binding "0009408=response to heat, 0006457=protein folding" "0005737=cytoplasm, 0005875=microtubule associated complex" "DmHsp40, HSP40/HDJ1, DNAJ1, dHDJ1, DROJ1, dHdj1, anon-WO0172774.135, hsp40, DnaJ1 64EF, CG10578, dhdj-1, dhdJ1, DNAJ-1, Hsp40, Hdj1, EU3500, HSP40, anon-WO0140519.166, Hsp-40, dnaJ like1, dHDJ1/HSP40, dnaJ-1, droj1, DroJ1, dhdj1" "IPR001623=DnaJ domain, IPR002939=Chaperone DnaJ, C-terminal, IPR008971=HSP40/DnaJ peptide-binding, IPR018253=DnaJ domain, conserved site" CG10578 16-Dec-15 2015_12 "ENSDARG00000041394(dnajb1b),ENSDARG00000015831(dnajb1a),ENSDARG00000052881(LOC569466)" YNL007C(SIS1) WBGene00001031(dnj-13) "ENSXETG00000020601(dnajb4),ENSXETG00000013144(DNAJB4),ENSXETG00000014155(DNAJB5)" "ENSMUSG00000036052(Dnajb5),ENSMUSG00000028035(Dnajb4),ENSMUSG00000005483(Dnajb1)" "ENSG00000137094(DNAJB5),ENSG00000162616(DNAJB4),ENSG00000132002(DNAJB1)" FBgn0031403 CG15387 http://flybase.net/reports/FBgn0031403.html protein_coding_gene IPR026317=Protein C10 CG15387 16-Dec-15 2015_12 ENSDARG00000030038(zgc:86838) ENSXETG00000023908(TNeu030m04.1) ENSMUSG00000072772(Grcc10) ENSG00000111678(C12orf57) "viable,visible" mesothoracic tergum FBgn0022279 l(2)IR4 lethal (2) IR4 http://flybase.net/reports/FBgn0022279.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0014209 l(1)TW9 lethal (1) TW9 http://flybase.net/reports/FBgn0014209.html FBgn0005119 gene "lethal(1)FMc, l(1)FMc" 16-Dec-15 2015_12 lethal FBgn0085533 CG40908 http://flybase.net/reports/FBgn0085533.html FBan0040908 protein_coding_gene 16-Dec-15 2015_12 FBgn0043903 dome domeless http://flybase.net/reports/FBgn0043903.html "FBgn0019901, FBgn0027236, FBgn0028267, FBgn0028288, FBgn0028311, FBgn0028326, FBgn0028335, FBgn0028344, FBgn0031056" protein_coding_gene "0019955=cytokine binding, 0046982=protein heterodimerization activity, 0004888=transmembrane signaling receptor activity" "0007616=long-term memory, 0001745=compound eye morphogenesis, 0008284=positive regulation of cell proliferation, 0045475=locomotor rhythm, 0006955=immune response, 0002009=morphogenesis of an epithelium, 0050829=defense response to Gram-negative bacterium, 0007424=open tracheal system development, 0007442=hindgut morphogenesis, 0007425=epithelial cell fate determination, open tracheal system, 0007298=border follicle cell migration, 0007350=blastoderm segmentation, 0045824=negative regulation of innate immune response, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development, 0007259=JAK-STAT cascade" "0016327=apicolateral plasma membrane, 0005886=plasma membrane, 0016324=apical plasma membrane" "l(1)G0321, l(1)G0282, l(1)G0217, verstopft, DOME, l(1)G0367, l(1)G0441, 142932_at, DOMELESS, l(1)G0264, mom, Domeless, anon-18DEb, l(1)G0218, Dome receptor, master of marelle, vsp, CG14226, l(1)G0405, Dome, CT33841, l(1)G0468" "IPR013783=Immunoglobulin-like fold, IPR003961=Fibronectin type III" CG14226 16-Dec-15 2015_12 "memory defective,RU486 conditional,visible,small body,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,recessive,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,developmental rate defective,wild-type,germline clone,locomotor rhythm defective,immune response defective,conditional,female sterile,viable" "wing vein,ectopic,wing,embryonic/larval spiracle,embryonic/larval posterior spiracle,filzkorper,stigmatophore,border follicle cell,somatic clone,embryonic abdominal segment 5,non-rescuable maternal effect,embryonic abdominal segment 4,posterior,embryonic thoracic segment,rescuable maternal effect,embryonic head,presumptive embryonic/larval tracheal system,embryonic/larval proventriculus,plasmatocyte,germline clone,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,abdominal 4 ventral denticle belt,egg chamber,posterior spiracle primordium,tracheal branch primordium,mouth hooks,egg chamber & basement membrane | apicalslbo.2.6,polar follicle cell,embryonic segment,embryonic hindgut,eye,eye disc anterior to the morphogenetic furrow,eye disc,midgut,embryonic abdominal segment,mesothoracic tergum,epithelium,interfollicle cell" DRSC19583 IE -0.495295078 2.477767577 -0.676930897 1.775472117 -0.035957473 0.365218287 FBgn0003169 put punt http://flybase.net/reports/FBgn0003169.html "FBgn0000467, FBgn0004912, FBgn0004920, FBgn0010942, FBgn0011375" protein_coding_gene "0005024=transforming growth factor beta-activated receptor activity, 0004672=protein kinase activity, 0017002=activin-activated receptor activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0005026=transforming growth factor beta receptor activity, type II, 0048185=activin binding, 0005524=ATP binding" "0001745=compound eye morphogenesis, 0032924=activin receptor signaling pathway, 0007424=open tracheal system development, 0006468=protein phosphorylation, 0007428=primary branching, open tracheal system, 0045705=negative regulation of salivary gland boundary specification, 0009953=dorsal/ventral pattern formation, 0048813=dendrite morphogenesis, 0010629=negative regulation of gene expression, 0007179=transforming growth factor beta receptor signaling pathway, 0048666=neuron development, 0008258=head involution, 0007391=dorsal closure, 0022008=neurogenesis, 0030718=germ-line stem cell maintenance, 0042078=germ-line stem cell division, 0007443=Malpighian tubule morphogenesis, 0007411=axon guidance" "0048179=activin receptor complex, 0005886=plasma membrane" "Activin-A-receptor-88CD, Atr, TGF-beta, TGF-B, AtrII, dlhC, l(3)10460, Act-r, l(3)j5A5, PUNT, punt, Put, Atr88CD, Tgf-r, STK-C, CG7904, Punt, dorsal holes C, activin receptor type II, pun, Atr-II, DPP receptor, atrII, TGF-beta-type-receptor-like, activin receptor" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR000333=Ser/Thr protein kinase, TGFB receptor, IPR000472=Activin types I and II receptor domain" CG7904 16-Dec-15 2015_12 "ENSDARG00000041516,ENSDARG00000044422(LOC100331890),ENSDARG00000011188(acvr2a)" WBGene00000900(daf-4) "ENSXETG00000021720(ACVR2A),ENSXETG00000020999(acvr2b)" "ENSMUSG00000052155(Acvr2a),ENSMUSG00000061393(Acvr2b)" "ENSG00000114739(ACVR2B),ENSG00000121989(ACVR2A)" " embryonic stage | stage 11-16 , embryonic stage | stage 6-11 , adult stage && oogenesis stage , larval stage | third instar , embryonic stage | stage 1-4 , embryonic stage | stage 5 , embryonic stage -- adult stage " " embryonic/larval foregut

, mesoderm

, oocyte

, imaginal disc

,

ubiquitous , pole cell

, embryonic/larval hindgut

, nurse cell

, embryonic/larval midgut

" " embryonic stage | stage 11-16 , embryonic stage | stage 14-16 , embryonic stage | stage 6-11 , embryonic stage | stage 11-13 , embryonic stage | stage 4 , embryonic stage | stage 5 " " embryonic/larval hindgut

, anterior embryonic/larval midgut

, mesoderm

, embryonic/larval midgut

, embryonic/larval foregut

,

ubiquitous , pole cell

" "visible,lethal,recessive,maternal effect,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,neuroanatomy defective,partially lethal - majority die,cold sensitive,viable,small body,wild-type,somatic clone" "female germline stem cell,male germline stem cell,heat sensitive,testis,spermatogonium,sensory mother cell & dorsal mesothoracic disc,crystal cell,plasmatocyte,leg,dorsal,ventral,eye,antenna,wing vein,ectopic,embryonic/first instar larval cuticle,embryonic head,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,wing,dorsocentral bristle,macrochaeta,embryonic dorsal epidermis,germline clone,pigment granule,morphogenetic furrow,eye disc,posterior,somatic clone,photoreceptor cell,dorsal branch primordium,primary pigment cell,tertiary pigment cell,intersegmental nerve,abdominal segmental nerve,somatic muscle,embryonic epidermis,wing margin,dorsal mesothorax,distal,sex comb,ommatidium,interommatidial bristle,dorsal closure embryo,dorsal cluster neuron & axon | somatic clone,dorsal cluster neuron & neurite | somatic clone,protocerebrum,optic lobe,fascicle,dorsal cluster neuron,heart primordium,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,salivary gland,Malpighian tubule,embryonic/larval dorsal branch,embryonic/larval lateral trunk,germline cell,embryo,anterior,embryonic/larval tracheal system,dorsal cluster neuron & neurite | somatic clone | conditional ts,wing vein L2,wing vein L3,wing vein L4,wing vein L5,anterior crossvein,wing cell,posterior compartment,scutum & macrochaetatsh-Gal4-1,scutum & macrochaetahs.PB,mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell,bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0024273 WASp WASp http://flybase.net/reports/FBgn0024273.html FBgn0039603 protein_coding_gene "0003779=actin binding, 0005515=protein binding" "0007520=myoblast fusion, 0007423=sensory organ development, 0016476=regulation of embryonic cell shape, 0030833=regulation of actin filament polymerization, 0035212=cell competition in a multicellular organism, 0035017=cuticle pattern formation, 0007409=axonogenesis, 0007413=axonal fasciculation, 0006900=membrane budding, 0016203=muscle attachment, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0001578=microtubule bundle formation, 0008407=chaeta morphogenesis, 0007286=spermatid development, 0072583=clathrin-mediated endocytosis, 0006886=intracellular protein transport, 0009913=epidermal cell differentiation, 0034314=Arp2/3 complex-mediated actin nucleation, 0003383=apical constriction, 0008582=regulation of synaptic growth at neuromuscular junction, 0008356=asymmetric cell division, 0045165=cell fate commitment" "0031594=neuromuscular junction, 0005737=cytoplasm, 0005634=nucleus, 0016028=rhabdomere, 0005902=microvillus, 0043234=protein complex" "dWASP, DmWASP, Wsp, Wasp, WASP, Wiscott-Aldrich syndrome protein, D-WASP, Dm WASP, wasp, WSP, CG1520, wsp, Wiskott-Aldrich syndrome protein" "IPR000095=CRIB domain, IPR003124=WH2 domain, IPR011026=Wiscott-Aldrich syndrome protein, C-terminal, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000697=WH1/EVH1 domain" CG1520 16-Dec-15 2015_12 "ENSDARG00000014113(wasla),ENSDARG00000006283(waslb),ENSDARG00000026350(wasb)" YOR181W(LAS17) WBGene00006957(wsp-1) "ENSXETG00000022129(wasl),ENSXETG00000011937(WAS)" "ENSMUSG00000031165(Was),ENSMUSG00000029684(Wasl)" "ENSG00000106299(WASL),ENSG00000015285(WAS)" "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,cell shape defective,lethal,neuroanatomy defective,male sterile,hypoactive,recessive,behavior defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,visible,rescuable maternal effect,partially lethal - majority die,some die during pupal stage,conditional,lethal - all die during embryonic stage" "embryonic myoblast,muscle attachment site,myoblast,plasma membrane | embryonic stage,dorsal acute muscle,embryonic/larval somatic muscle,ectoderm | extended germ band stage,head bristle,adult abdominal sensillum,leg & microchaeta3450),adult thorax & microchaeta3450),macrochaeta,interommatidial bristle,supernumerary,tormogen cell,trichogen cell,interommatidial bristle & eo neuron | supernumerary3450),interommatidial bristle & tormogen cell3450),interommatidial bristle & trichogen cell3450),sensory mother cell,embryonic/larval neuromuscular junction,synaptic vesicle | third instar larval stage3450),NMJ bouton,rhabdomere | adult stage | somatic clone3450),somatic clone,spermatid cyst,seminal vesicle,head cyst cell,actin filament3450)arm.PS, WASpH242D.UAS,macrochaeta & adult head | somatic clone,microchaeta & adult head | somatic clone,neuromuscular junction | larval stage,bouton,rhabdomere,embryonic peripheral nervous system & neuron | supernumerary | germ-line clone3450),embryonic peripheral nervous system & external sensory organ | germ-line clone3450),RP2 motor neuron,adult thorax & microchaeta & external sensory organ precursor cell IIa3450),adult thorax & microchaeta & external sensory organ precursor cell IIb3450),microchaeta,dorsocentral bristle,scutellar bristle,notopleural bristle,microvillus & eye photoreceptor cell | somatic clone,actin filament & eye photoreceptor cell | somatic clone,eye disc,ventral nerve cord,rescuable maternal effect,denticle,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,external sensory organ,mesothoracic bristle & eo neuron | supernumerary,mesothoracic bristle & tormogen cell,mesothoracic bristle & trichogen cell,chaeta,actin filament, with Df(3R)3450/WASp1, arm.PS,adult brain,mitochondrionelav.PU,neuromuscular junctionC57,dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional" FBgn0020493 Dad Daughters against dpp http://flybase.net/reports/FBgn0020493.html "FBgn0024521, FBgn0025250, FBgn0062662" protein_coding_gene "0005515=protein binding, 0030617=transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity, 0003700=sequence-specific DNA binding transcription factor activity" "0007476=imaginal disc-derived wing morphogenesis, 0030512=negative regulation of transforming growth factor beta receptor signaling pathway, 0016335=morphogenesis of larval imaginal disc epithelium, 0007443=Malpighian tubule morphogenesis, 0008582=regulation of synaptic growth at neuromuscular junction, 0048635=negative regulation of muscle organ development, 0016477=cell migration, 0031290=retinal ganglion cell axon guidance, 0007488=histoblast morphogenesis, 0090254=cell elongation involved in imaginal disc-derived wing morphogenesis, 0007448=anterior/posterior pattern specification, imaginal disc, 0042325=regulation of phosphorylation, 0030718=germ-line stem cell maintenance, 0035214=eye-antennal disc development, 0061353=BMP signaling pathway involved in Malpighian tubule cell chemotaxis, 0017015=regulation of transforming growth factor beta receptor signaling pathway, 0045886=negative regulation of synaptic growth at neuromuscular junction" 0005667=transcription factor complex "Daughters against DPP, anon-EST:fe1F5, daughter against dpp, Daughters against dpp, DAD, dad, Daughters against Dpp, EP3196, EP(3)3196, Dad1, 1883, anon-fast-evolving-1F5, CG5201, daughters against dpp, l(3)j1E4" "IPR003619=MAD homology 1, Dwarfin-type, IPR013019=MAD homology, MH1, IPR017855=SMAD domain-like, IPR001132=SMAD domain, Dwarfin-type, IPR013790=Dwarfin, IPR008984=SMAD/FHA domain" CG5201 16-Dec-15 2015_12 larval stage | third instar dorsal mesothoracic disc | restricted

"partially lethal - majority die,visible,lethal,recessive,endocytosis defective,dominant,neuroanatomy defective,cell lethalcell lethal,somatic clone,mitotic cell cycle defective,cell autonomous,cell non-autonomous,cell shape defective,increased cell death,neurophysiology defective" "wing vein L2,wing vein,dorsal appendage,ectopic,wing,NMJ bouton,supernumerary,female germline stem cell,bouton,neuromuscular junction,wing disc,cell autonomous,cell non-autonomous,medial,spermatocyte,spermatogonium,male germline stem cell,testis,germline cell,female | larval stage,germline cyst,wing margin,eye disc & peripodial epitheliumc311,peripodial epithelium,ventral thoracic disc,wing pouch,eye photoreceptor cell stalk,lamina tangential neuron,lamina intrinsic neuron,lamina,lamina anlage glial cell,dorsal branch primordium,tracheal tip cell | embryonic stage,neuromuscular junctionRapGAP1-OK6,somatic clone,fat body,maxillary palpus,vibrissae,amnioserosa,embryonic dorsal epidermis,filamentous actinpAS,egg operculum,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,embryonic anterior Malpighian tubule,histoblast,histoblast nest,wing vein L4,wing vein L5,anterior crossvein,adult brain" FBgn0004567 slp2 sloppy paired 2 http://flybase.net/reports/FBgn0004567.html protein_coding_gene "0008134=transcription factor binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0008301=DNA binding, bending, 0003690=double-stranded DNA binding" "0045787=positive regulation of cell cycle, 0007365=periodic partitioning, 0035058=nonmotile primary cilium assembly, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0048665=neuron fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0009888=tissue development, 0002052=positive regulation of neuroblast proliferation, 0007380=specification of segmental identity, head, 0045665=negative regulation of neuron differentiation, 0007346=regulation of mitotic cell cycle, 0009792=embryo development ending in birth or egg hatching, 0009953=dorsal/ventral pattern formation, 0016199=axon midline choice point recognition" "0005667=transcription factor complex, 0005634=nucleus" "slp, CG2939, Slp, Sloppy-paired, Dmslp2, Sloppy paired 2, SLOPPY-PAIRED, sloppy pair, FD7, sloppy-paired 2, sloppy-paired, SLP, Slp2, FoxG, sloppy paired" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain, IPR018122=Fork head domain conserved site1" CG2939 16-Dec-15 2015_12 "ENSDARG00000070769(foxg1a),ENSDARG00000068380(foxg1c),ENSDARG00000032705" WBGene00001434(fkh-2) ENSXETG00000010247(FOXG1) ENSMUSG00000020950(Foxg1) ENSG00000176165(FOXG1) " embryonic stage | stage >7 , embryonic stage , embryonic stage | stage 6 , embryonic stage | stage 4 | late , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | stage >=13 " " labral segment

, mandibular segment

, intercalary segment

, organism | gap

,

segment polarity , embryonic procephalic segment | lateral

,

71-85% egg length & ventral , organism | pair rule

, organism | 70-80% egg length & dorsal

, organism | even pair rule

, ventral nerve cord

, proventriculus

" " embryonic stage | stage 7 , embryonic stage | stage 8 " " organism | pair rule

,

segment polarity " "lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "embryonic/larval dorsal vessel,abdominal 8 ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast NB4-2,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,cuticle,denticle belt" FBgn0038487 TwdlW TweedleW http://flybase.net/reports/FBgn0038487.html protein_coding_gene 0005214=structural constituent of chitin-based cuticle "0040003=chitin-based cuticle development, 0010171=body morphogenesis" 0005578=proteinaceous extracellular matrix "CG4060, Tweedle W" IPR004145=Domain of unknown function DUF243 CG4060 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0024179 wit wishful thinking http://flybase.net/reports/FBgn0024179.html "FBgn0014282, FBgn0015807, FBgn0027362, FBgn0027993, FBgn0035493" protein_coding_gene "0004675=transmembrane receptor protein serine/threonine kinase activity, 0005524=ATP binding, 0005026=transforming growth factor beta receptor activity, type II, 0004702=receptor signaling protein serine/threonine kinase activity, 0004672=protein kinase activity" "0007178=transmembrane receptor protein serine/threonine kinase signaling pathway, 0048813=dendrite morphogenesis, 0007528=neuromuscular junction development, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0008582=regulation of synaptic growth at neuromuscular junction, 0007165=signal transduction, 0007274=neuromuscular synaptic transmission, 0046331=lateral inhibition, 0006468=protein phosphorylation" "0055037=recycling endosome, 0045202=synapse, 0005769=early endosome, 0016020=membrane, 0005886=plasma membrane" "WIT, 1262/15, Serine/threonine kinase-D, Wit, l(3)S126215, Wishful thinking, SE20, Stk-D, Wishful Thinking, STK-D, l(3)64Aa, BMP, CG10776, Wit-C, Bone Morphogenetic Protein, l(3)SH12, ALK3/BMPRII" "IPR000719=Protein kinase domain, IPR000333=Ser/Thr protein kinase, TGFB receptor, IPR000472=Activin types I and II receptor domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG10776 16-Dec-15 2015_12 "ENSDARG00000020057(bmpr2b),ENSDARG00000011941(bmpr2a)" WBGene00000900(daf-4) ENSXETG00000022074(BMPR2) ENSMUSG00000067336(Bmpr2) ENSG00000204217(BMPR2) " embryonic stage | stage 11-14 , embryonic stage | stage >=15 , embryonic stage | stage 16-17 , embryonic stage | stage 14 " " ventral nerve cord primordium | restricted

, embryonic central nervous system

, embryonic/larval midgut | restricted

, amnioserosa

, embryonic central nervous system | restricted

" " larval stage , embryonic stage | stage 13 , larval stage | first instar -- L | second instar , larval stage | third instar , embryonic stage | stage 13-17 , embryonic stage | stage 13-14 , embryonic stage | stage 16-17 " " larval brain

, VUM neuron

, ventral nerve cord

, imaginal disc

, lateral cord neuron

, ventral nerve cord primordium | restricted

, RP2 neuron

, motor neuron

" "neuroanatomy defective,viable,fertile,lethal,recessive,neurophysiology defective,wild-type,lethal - all die before end of P-stage,some die during pharate adult stage,size defective,maternal effect,visible,circadian rhythm defective" "bouton,neuromuscular junction,embryonic/larval muscle system,synapse,NMJ bouton,A2 neuron,A3 neuron,embryonic/larval neuromuscular junction,type I bouton,supernumerary,leg,tarsal segment,metathoracic femur,metathoracic tibia,femur,tibia,postsynaptic membrane,synapse | larval stage,wing vein L5,posterior crossvein,synapseRapGAP1-OK6,chaeta" FBgn0026379 Pten Phosphatase and tensin homolog http://flybase.net/reports/FBgn0026379.html FBgn0032201 protein_coding_gene "0004726=non-membrane spanning protein tyrosine phosphatase activity, 0016314=phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity, 0004438=phosphatidylinositol-3-phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0051800=phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity, 0000287=magnesium ion binding, 0004722=protein serine/threonine phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0030165=PDZ domain binding, 0051717=inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity, 0003779=actin binding" "0030336=negative regulation of cell migration, 0051895=negative regulation of focal adhesion assembly, 0035206=regulation of hemocyte proliferation, 0051898=negative regulation of protein kinase B signaling, 0008283=cell proliferation, 0042052=rhabdomere development, 0046856=phosphatidylinositol dephosphorylation, 0006470=protein dephosphorylation, 0042594=response to starvation, 0040015=negative regulation of multicellular organism growth, 0030036=actin cytoskeleton organization, 0008361=regulation of cell size, 0007425=epithelial cell fate determination, open tracheal system, 0019915=lipid storage, 0046855=inositol phosphate dephosphorylation, 0016322=neuron remodeling, 0006915=apoptotic process, 1901888=regulation of cell junction assembly, 0046621=negative regulation of organ growth, 0010506=regulation of autophagy, 0009887=organ morphogenesis, 0007436=larval salivary gland morphogenesis, 0031647=regulation of protein stability, 0090175=regulation of establishment of planar polarity, 0007552=metamorphosis, 0046627=negative regulation of insulin receptor signaling pathway, 0008360=regulation of cell shape, 0009987=cellular process, 0030308=negative regulation of cell growth, 0006914=autophagy, 0008286=insulin receptor signaling pathway, 0031104=dendrite regeneration, 0071711=basement membrane organization, 0007155=cell adhesion, 0045926=negative regulation of growth, 0050773=regulation of dendrite development, 0008285=negative regulation of cell proliferation, 0034613=cellular protein localization, 0040014=regulation of multicellular organism growth, 0045792=negative regulation of cell size, 0007015=actin filament organization, 0002164=larval development, 0035069=larval midgut histolysis, 0035011=melanotic encapsulation of foreign target, 0007525=somatic muscle development, 0046620=regulation of organ growth, 0045786=negative regulation of cell cycle, 0006629=lipid metabolic process, 0051726=regulation of cell cycle, 0009888=tissue development, 0007010=cytoskeleton organization, 0048681=negative regulation of axon regeneration" "0005634=nucleus, 0005737=cytoplasm" "pten, DPTEN, Pten, Drosophila phosphatase and tensin homologue deleted on chromosome 10, Phosphatase and tensin homologue, PTEN3, PTEN, phosphatidylinositol (3,4,5)-trisphosphate phosphatase, PtdIns(3,4,5)P3 phosphatase, dpten, phosphatase and tensin homolog, CG5671, dPten, dPTEN, PI 3-phosphatase" "IPR016130=Protein-tyrosine phosphatase, active site, IPR029021=Protein-tyrosine phosphatase-like, IPR000008=C2 domain, IPR017361=Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN, IPR000340=Dual specificity phosphatase, catalytic domain, IPR014020=Tensin phosphatase, C2 domain, IPR029023=Tensin phosphatase, lipid phosphatase domain" CG5671 16-Dec-15 2015_12 "ENSDARG00000056623(ptenb),ENSDARG00000071018(ptena)" ENSXETG00000009268(PTEN) ENSMUSG00000013663(Pten) ENSG00000171862(PTEN) "visible,size defective,decreased cell size,somatic clone,increased cell size,increased cell number,dominant,neurophysiology defective,neuroanatomy defective,wild-type,lethal,recessive,hyperplasia,lethal - all die before end of larval stage,some die during third instar larval stage,viable,large body,stress response defective,planar polarity defective,cell autonomous,some die during larval stage,neoplasia,decreased cell number,partially lethal - majority die,developmental rate defective,lethal - all die before end of pupal stage,partially,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,long lived,RU486 conditional,small body,aging defective,short lived,chemical resistant,heat sensitive,immune response defective,increased cell growth" "eye,ommatidium,embryonic/larval midgut,somatic clone,egg,germline clone,maternal effect,pole cell,cleavage stage embryo,blastoderm embryo,gastrula embryo,nurse cell & actin cytoskeleton | germ-line clone,nurse cell,nurse cell & nucleus | germ-line clone,eye photoreceptor cell,interommatidial bristle,wing margin bristle,eye disc,wing,NMJ bouton,photoreceptor cell,cell autonomous,rhabdomere | cell autonomous | somatic clone,wing & cell | somatic clone,wing hair,ectopic,crossvein,ommatidial precursor cluster,dorsal multidendritic neuron ddaC,epithelial cell,lipid particle & nurse cell | somatic clone,rhabdomere,dendrite | cell autonomous | somatic clone,wing disc,tracheal primordium,mesothoracic tracheal primordium,metathoracic tracheal primordium,abdominal tracheal primordium 1,abdominal tracheal primordium 2,adult head,glial cell,supernumerary,optic lobe,head capsule,posterior compartment,wing blade,embryo | dorsal closure stage,embryonic leading edge cell,prothoracic gland,embryonic/larval corpus allatum,puparium,embryonic/larval salivary gland,embryonic/larval fat body,dorsal compartment,adult heart,fat body,cell cycleey.PH,pigment cell,lens,rhabdomereGMR.PF,lipid droplet & larval oenocyteppl.PP,dendrite | larval stageppk.PG,muscle cell,embryonic/larval neuroblast,posterior signalling centre of lymph gland primary lobe | third instar larval stage,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage,segment border muscle,A1-7 dorsal acute muscle 1,embryonic/first instar larval cuticle | first instar larval stage,chaeta,mesothoracic tergum,heat sensitive,cell junction | pupal stage | heat sensitiveen.PU, GAL80ts.ë±Tub84B,adult cuticle,somatic clone | third instar larval stage" DRSC03402 I 0.079375872 -2.655570592 0.197480659 0.198512374 0.05677846 -0.27793771 FBgn0033438 Mmp2 Matrix metalloproteinase 2 http://flybase.net/reports/FBgn0033438.html "FBgn0010512, FBgn0061593" protein_coding_gene "0008270=zinc ion binding, 0004175=endopeptidase activity, 0004222=metalloendopeptidase activity" "0097156=fasciculation of motor neuron axon, 0006508=proteolysis, 0071711=basement membrane organization, 0007426=tracheal outgrowth, open tracheal system, 0046529=imaginal disc fusion, thorax closure, 0042060=wound healing, 0046331=lateral inhibition, 0007561=imaginal disc eversion, 0090090=negative regulation of canonical Wnt signaling pathway, 0040037=negative regulation of fibroblast growth factor receptor signaling pathway, 0035202=tracheal pit formation in open tracheal system, 0034769=basement membrane disassembly, 0045216=cell-cell junction organization, 0048477=oogenesis, 0007505=adult fat body development, 0030178=negative regulation of Wnt signaling pathway, 0002218=activation of innate immune response, 0007424=open tracheal system development, 0008045=motor neuron axon guidance" "0031012=extracellular matrix, 0030425=dendrite, 0009897=external side of plasma membrane, 0005886=plasma membrane" "dmmp2, anon-WO0118547.84, matrix metalloproteinase, l(2)02353, MMP2, Dm2-MMP, CG1794, matrix metalloprotease 2, Matrix metalloproteinase, dm-2MMP, 2-MMP, mmp2, Matrix Metalloprotinase 2" "IPR018487=Hemopexin-like repeats, IPR001818=Peptidase M10, metallopeptidase, IPR002477=Peptidoglycan binding-like, IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR000585=Hemopexin-like domain, IPR021190=Peptidase M10A" CG1794 16-Dec-15 2015_12 "ENSDARG00000018896,ENSDARG00000025111,ENSDARG00000058876(LOC572034),ENSDARG00000051962(LOC100332442)" WBGene00016283(C31B8.8) ENSXETG00000025032(mmp15) "ENSMUSG00000029436(Mmp17),ENSMUSG00000023903(Mmp25)" ENSG00000099953(MMP11) " larval stage | third instar , adult stage | male , embryonic stage&&larval stage&&pupal stage , adult stage | female " " eye disc

, lamina

, larval optic lobe

, morphogenetic furrow | posterior to

, dorsal mesothoracic disc

" "lethal,recessive,melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,sterile,hyperplasia" "tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,wing,leg,basement membrane | pupal stage,mesothoracic tergum,gastric caecum,embryonic/larval proventriculus,dendritic arborizing neuron,embryonic/larval transverse connective,dorsal air sac primordium,wing disc,intersegmental nerve branch ISNb of A1-7,head,interommatidial bristle,ommatidium,intersegmental nerve branch ISNb of A1-7 | embryonic stage,segmental nerve branch SNa of A1-7 | embryonic stage,adult thorax,embryonic/larval transverse connective | third instar larval stage,dorsal air sac primordium | third instar larval stage,wing disc | third instar larval stage" DRSC22024 K 0.076338193 0.742320534 -0.090025995 0.069754853 -2.809413098 -0.329799802 FBgn0001233 Hsp83 Heat shock protein 83 http://flybase.net/reports/FBgn0001233.html "FBgn0004639, FBgn0010233, FBgn0011792, FBgn0016742, FBgn0024852, FBgn0044664" protein_coding_gene "0005524=ATP binding, 0051082=unfolded protein binding, 0042623=ATPase activity, coupled" "0007098=centrosome cycle, 0008285=negative regulation of cell proliferation, 0008595=anterior/posterior axis specification, embryo, 0007015=actin filament organization, 0010529=negative regulation of transposition, 0007465=R7 cell fate commitment, 0006457=protein folding, 0019094=pole plasm mRNA localization, 0007052=mitotic spindle organization, 0045187=regulation of circadian sleep/wake cycle, sleep, 0008360=regulation of cell shape, 0048477=oogenesis, 0008293=torso signaling pathway, 0043248=proteasome assembly, 0007283=spermatogenesis, 0009631=cold acclimation, 0009408=response to heat" "0005705=polytene chromosome interband, 0005886=plasma membrane, 0005813=centrosome, 0005811=lipid particle, 0048471=perinuclear region of cytoplasm, 0005737=cytoplasm" "HSP90, hsp82, ms(3)08445, 83, DmHsp83, Hsp82, anon-WO0140519.209, HSP82, hsp84, heat shock protein 83, E(sev)3A, E(sina)2, anon-WO0068693, ORF1, anon-EST:Liang-2.53, Su(Raf)3A, Hsp90, heat-shock protein 90 kDa, hsp90, DMHSP82, stc, HSP83, en(lz)3C/4C, clone 2.53, hsp83, CG1242, Enhancer of sevenless 3A, 143198_at, 83K HSP, Enhancer of seven in absentia 2, scratch, l(3)j5C2" "IPR019805=Heat shock protein Hsp90, conserved site, IPR020575=Heat shock protein Hsp90, N-terminal, IPR001404=Heat shock protein Hsp90 family, IPR020568=Ribosomal protein S5 domain 2-type fold, IPR003594=Histidine kinase-like ATPase, C-terminal domain" CG1242 16-Dec-15 2015_12 "ENSDARG00000029150(hsp90ab1),ENSDARG00000024746(hsp90a.2),ENSDARG00000010478(hsp90a.1)" "YPL240C(HSP82),YMR186W(HSC82)" WBGene00000915(daf-21) "ENSXETG00000010896(hspcb),ENSXETG00000010251(HSP90AA1),ENSXETG00000024415()" "ENSMUSG00000021270(Hsp90aa1),ENSMUSG00000023944(Hsp90ab1)" "ENSG00000080824(HSP90AA1),ENSG00000096384(HSP90AB1)" "lethal,recessive,viable,lethal - all die during third instar larval stage,developmental rate defective,fertile,locomotor rhythm defective,male sterile,female fertile,behavior defective,female semi-fertile,cell polarity defective,lethal - all die before end of pupal stage,partially lethal,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,short lived,male,partially lethal - majority die,female,visible,cell cycle defective" "spermatid,Nebenkern,spermatozoon,anterior dorsocentral bristle,posterior dorsocentral bristle,humeral bristle,scutellar bristle,supernumerary,metathoracic bristle,mesothoracic bristle,embryonic abdominal segment,maternal effect,spermatocyte,primary spermatocyte cyst,spermatid axoneme,Nebenkern derivative,primary spermatocyte,neuroblast,mitotic cell cycle,centrosome,egg chamber,nurse cell,egg,dorsal appendage,chaeta,photoreceptor cell R7,secondary pigment cell,wing,eye,dorsal" DRSC08664 IEK 0.742417259 1.779918004 0.744652459 -1.817842774 1.629574 2.337558348 FBgn0000179 bi bifid http://flybase.net/reports/FBgn0000179.html "FBgn0002996, FBgn0003183, FBgn0004104" protein_coding_gene "0005515=protein binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0048100=wing disc anterior/posterior pattern formation, 0007476=imaginal disc-derived wing morphogenesis, 0007472=wing disc morphogenesis, 0001745=compound eye morphogenesis, 0035265=organ growth, 0048066=developmental pigmentation" 0005634=nucleus "BI, optomoter blind, Optimotor-blind, lethal(l)optomotor-blind, omb, l(1)bi, dm-omb, Dm-OMB, optomotor blind, optomotor-blind, Dm-omb, OMB, CG3578, Optomotor-blind, T3, TBX2, Quadroon, Omb, optimotor blind, l(1)omb, Optomotor blind, optomer-blind, optomotor-blind gene, optomotorblind, Qd" "IPR001699=Transcription factor, T-box, IPR008967=p53-like transcription factor, DNA-binding, IPR018186=Transcription factor, T-box, conserved site, IPR021101=Optomotor-blind protein, N-terminal" CG3578 16-Dec-15 2015_12 "ENSDARG00000002216(tbx3),ENSDARG00000006120(tbx2b),ENSDARG00000018025(tbx2a)" "ENSXETG00000020557(Q3SA48_XENTR),ENSXETG00000006579(TBX3)" "ENSMUSG00000018604(Tbx3),ENSMUSG00000000093(Tbx2)" "ENSG00000121068(TBX2),ENSG00000135111(TBX3)" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 8 , prepupal stage , embryonic stage | stage 11-16 , adult stage , embryonic stage | stage 11 , embryonic stage | stage 17 , embryonic stage | stage 13-15 , embryonic stage | stage 10 " " procephalic segment

, eye-antennal disc

, inner proliferation zone

, ventral nervous system | segmentally repeated

, larval brain

, medulla cortex

, suture &&of larval outer optic anlage

, antennal segment

, larval optic lobe

, antenno-maxillary complex

, lamina neuropil

, peripheral nervous system precursor cluster

, ventral nerve cord

, protocerebrum

, embryonic peripheral nervous system

, ventral body

" larval stage | third instar dorsal mesothoracic disc | restricted

"visible,dominant,viable,fertile,recessive,eye color defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,partially lethal - majority die,sterile,male,body color defective,neurophysiology defective,cell autonomous,somatic clone,planar polarity defective,cell non-autonomous,lethal - all die before end of P-stage,some die during pharate adult stage,optomotor response defective,behavior defective,semidominant,visual behavior defective,phototaxis defective,heat sensitive,size defective,lethal - all die before end of larval stage,female,some die during larval stage" "wing vein,wing vein L3,distal,wing margin,wing,proximal,eye,pigment cell,tergite,female,posterior,horizontal system neuron,optic chiasma,lobula,anterior,abdominal tergite & macrochaeta,sternite | anterior & trichome,wing vein L4,adult cuticle & abdominal segment | male,somatic clone,adult abdominal segment 3,ectopic,adult abdominal segment,posterior compartment,hypandrial bristle,hypandrial hair,hypandrium,anal plate,epiproct,hypoproct,clasper long bristle,dorsal,abdominal tergite & trichome,abdominal sternite & trichome,adult abdomen,wing disc,anterior/posterior compartment boundary,adult cuticle & abdomen | somatic clone | cell autonomous,microchaeta,abdominal tergite | posterior & trichome,lobula plate,optic lobe,dorsal margin photoreceptor,heat sensitive,wing hinge,wing sensillum,wing pouch,wing vein L5,cell non-autonomous,arista,ommatidium,leg,adult cuticle & abdomen | somatic cloneUbx.PdC,tarsal segment,male,wing blade" FBgn0000591 E(spl)m8-HLH "Enhancer of split m8, helix-loop-helix" http://flybase.net/reports/FBgn0000591.html protein_coding_gene "0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0046982=protein heterodimerization activity, 0042803=protein homodimerization activity" "0048749=compound eye development, 0045165=cell fate commitment, 0007498=mesoderm development, 0008587=imaginal disc-derived wing margin morphogenesis, 0007219=Notch signaling pathway, 0048813=dendrite morphogenesis, 0016360=sensory organ precursor cell fate determination, 0048666=neuron development, 0010629=negative regulation of gene expression, 0007422=peripheral nervous system development, 0045468=regulation of R8 cell spacing in compound eye, 0007173=epidermal growth factor receptor signaling pathway, 0007398=ectoderm development, 0000122=negative regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "clone 1.71, HLHm8, E(spl)bHLH, m8, Enhancer of Split, Hes, Enhancer of split m8, E(spl)-m8, Enhancer-of-split, E(spl)M8, Espl, CG8365, E(spl) m8, E(spl), e(spl), E(spl)-C, E(spl)m8, M8, anon-EST:Liang-1.71, Su(H)[[m8]], E(Spl), En(spl), enhancer of split, enhancer-of-split-m8, En(spl)-C, bHLHb36, l(3)96Fd, Enhancer of split" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR003650=Orange domain" CG8365 16-Dec-15 2015_12 "ENSDARG00000069675(her8.2),ENSDARG00000016363(her8a)" " embryonic stage | stage 11-12 , embryonic stage | stage 5 , embryonic stage , embryonic stage | 2-10 hr , embryonic stage | stage 10 , embryonic stage | stage 11-14 , embryonic stage | stage 7-11 , embryonic stage | stage 11 " " mesoderm

, organism | striped

, ventral neurogenic region

, larval brain

, embryonic central nervous system

, posterior midgut proper primordium

, stomatogastric nervous system | primordium

, embryonic optic lobe primordium

, peripheral nervous system

, ectoderm

, supraesophageal ganglion

, mesectoderm

, epidermis | restricted

" "lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,neurogenic phenotype,cell lethalcell lethal,somatic clone,viable,dominant,neuroanatomy defective" "scutellar bristle,ectopic,scutum & macrochaeta & adult-537.4,adult abdomen & macrochaeta-537.4,adult head & macrochaeta-537.4,eye,macrochaeta | ectopic & scutellum455.2,socket,nervous system,chaeta & mesothoracic tergum,external sensory organ precursor cell,morphogenetic furrow,muscle founder cell,embryonic/larval somatic muscle,peripheral nervous system,anterior orbital bristle,postvertical bristle,interocellar bristle,crossvein,central nervous system,macrochaeta,microchaeta,wing vein,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutum & macrochaetah-1J3,embryonic epidermis,macrochaeta & scutellum455.2,interommatidial bristle,somatic clone,epidermis,mesothoracic tergum,corpus cardiacum primordium,adult peripheral nervous system,microchaeta & mesothoracic tergum,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,ommatidium,eye photoreceptor cell,embryonic neuroblast,supernumerary,germline clone,embryonic/larval corpus cardiacum,eo neuron,dorsal triple row,chemosensory ventral triple row bristle,campaniform sensillum of anterior crossvein,campaniform sensillum L3-2 of wing vein L3,campaniform sensillum L3-3 of wing vein L3,chordotonal organ precursor cell & ventral thoracic disc-109-68,chaeta,external sensory organ,neuroblast" FBgn0003254 rib ribbon http://flybase.net/reports/FBgn0003254.html FBgn0034424 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0008104=protein localization, 0008406=gonad development, 0008360=regulation of cell shape, 0007435=salivary gland morphogenesis, 0007428=primary branching, open tracheal system, 0035149=lumen formation, open tracheal system, 0061024=membrane organization, 0007426=tracheal outgrowth, open tracheal system, 0016477=cell migration, 0035297=regulation of Malpighian tubule diameter, 0007442=hindgut morphogenesis, 0007424=open tracheal system development, 0007427=epithelial cell migration, open tracheal system, 0007443=Malpighian tubule morphogenesis, 0008258=head involution, 0007431=salivary gland development, 0006355=regulation of transcription, DNA-templated, 0007010=cytoskeleton organization, 0007391=dorsal closure, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0007417=central nervous system development" 0005634=nucleus "gene 5, RIB, CG7230, fus1, SGP cluster fusion defects 1" "IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR007889=DNA binding HTH domain, Psq-type, IPR009057=Homeodomain-like" CG7230 16-Dec-15 2015_12 ENSXETG00000005594(btbd14b) "ENSMUSG00000001910(Nacc1),ENSMUSG00000026932(Nacc2)" ENSG00000148411(NACC2) "lethal,recessive,cell polarity defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "gonad,gonadal sheath proper primordium,presumptive embryonic/larval tracheal system,embryonic/first instar larval cuticle,dorsal,denticle belt,denticle,trachea,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval ganglionic branch,embryonic/larval lateral trunk,embryonic/larval salivary gland,embryonic/larval salivary gland duct,embryonic epidermis,embryonic/larval hindgut,presumptive embryonic salivary gland,Malpighian tubule,dorsal closure embryo,midgut constriction,dorsal hair,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,embryonic/larval midgut,head,embryonic/larval salivary gland common duct,embryonic/larval tracheal system,peripheral nervous system precursor cluster,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,dorsal trunk primordium,embryo,embryonic head" FBgn0011604 Iswi Imitation SWI http://flybase.net/reports/FBgn0011604.html "FBgn0010436, FBgn0066055" protein_coding_gene "0000166=nucleotide binding, 0008134=transcription factor binding, 0005524=ATP binding, 0005515=protein binding, 0070615=nucleosome-dependent ATPase activity, 0003678=DNA helicase activity, 0016887=ATPase activity, 0003677=DNA binding, 0008094=DNA-dependent ATPase activity, 0031491=nucleosome binding" "0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated, 0045892=negative regulation of transcription, DNA-templated, 0006334=nucleosome assembly, 0042752=regulation of circadian rhythm, 0006325=chromatin organization, 0006338=chromatin remodeling, 0042766=nucleosome mobilization, 0016584=nucleosome positioning, 0035076=ecdysone receptor-mediated signaling pathway, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035063=nuclear speck organization, 0043044=ATP-dependent chromatin remodeling, 0007517=muscle organ development, 0006351=transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter, 0045893=positive regulation of transcription, DNA-templated, 0006333=chromatin assembly or disassembly" "0016589=NURF complex, 0031213=RSF complex, 0005634=nucleus, 0008623=CHRAC, 0000790=nuclear chromatin, 0031010=ISWI-type complex, 0005700=polytene chromosome, 0005667=transcription factor complex, 0016590=ACF complex, 0035060=brahma complex" "p140, iswi, imitation SWI, ISWI ATPase, p140/ISWI, SWI, ISWI, dNURF, NURF 140, Imitation switch, Nucleosome remodeling factor, NURF-140, ACF, Nurf-140, Nucleosome remodeling factor - 140kD, CG8625, imitation-SWI, Imitation SW, NURF, ISW, dISWI, dCHRAC, CHRAC, imitation switch, anon-EP1279744.124" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001005=SANT/Myb domain, IPR020838=DBINO domain, IPR029915=ISWI family, IPR015194=ISWI, HAND domain, IPR009057=Homeodomain-like, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR017884=SANT domain, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain, IPR015195=SLIDE domain" CG8625 16-Dec-15 2015_12 ENSDARG00000012776(LOC559803) "YOR304W(ISW2),YBR245C(ISW1)" WBGene00002169(isw-1) ENSXETG00000017566(smarca5) "ENSMUSG00000031715(Smarca5),ENSMUSG00000031099(Smarca1)" "ENSG00000153147(SMARCA5),ENSG00000102038(SMARCA1)" " embryonic stage | stage >=13 , embryonic stage--pupal stage , embryonic stage | stage <13 , adult stage | female " " gonad

, organism

, embryonic central nervous system

" embryonic stage -- adult stage "wild-type,lethal,lethal - all die before end of larval stage,some die during larval stage,recessive,female sterile,tumorigenic,visible,somatic clone,eye color defective,mitotic cell cycle defective,heat sensitive,non-enhancer of variegation,non-suppressor of variegation,viable,locomotor rhythm defective" "hemocyte,supernumerary,wing disc,polytene chromosome | male, with Iswi1,dorsocentral bristle,ovariole,germline clone,genitalia,somatic clone,adult head,adult thoracic segment,polytene chromosome,embryonic/larval hemocyte,female germline stem cell,follicle stem cell,X chromosome | male,eye,ommatidium,eye photoreceptor cell,polytene chromosome | male limited,condensed chromosome, with IswiK159R.UAS.TIvirHA1, da.G32,polytene chromosome | male, with Iswi2,polytene chromosomeey.PH,mechanosensory chaeta,euchromatinda.G32,condensed chromosomeda.G32,condensed chromosome, with Iswi2, da.G32,embryonic/larval brain,mesothoracic tergum" DRSC07446 EK -1.287038471 -0.637395978 -2.333316161 0.205063746 0.459351224 1.804933101 FBgn0001942 eIF-4a Eukaryotic initiation factor 4a http://flybase.net/reports/FBgn0001942.html "FBgn0013406, FBgn0013523, FBgn0015864, FBgn0022247, FBgn0024969, FBgn0062252" protein_coding_gene "0003724=RNA helicase activity, 0003729=mRNA binding, 0005524=ATP binding, 0000339=RNA cap binding, 0017116=single-stranded DNA-dependent ATP-dependent DNA helicase activity, 0003743=translation initiation factor activity" "0007067=mitotic nuclear division, 0002168=instar larval development, 0007052=mitotic spindle organization, 0030718=germ-line stem cell maintenance, 0009950=dorsal/ventral axis specification, 0051297=centrosome organization, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007279=pole cell formation, 0048132=female germ-line stem cell asymmetric division, 0006413=translational initiation, 0007446=imaginal disc growth, 0048477=oogenesis, 0006268=DNA unwinding involved in DNA replication, 0000022=mitotic spindle elongation, 0006974=cellular response to DNA damage stimulus" "0072686=mitotic spindle, 0005813=centrosome, 0005829=cytosol, 0005634=nucleus, 0043186=P granule, 0016281=eukaryotic translation initiation factor 4F complex, 0005875=microtubule associated complex" "l(2)162, Su(dpp)YE9, L(2L)162, eIF-4a-I, Eif4a, EiF4A, EIF-4a, Dm-eIF4A, DmRH2, l(2)26Ac, eif4a, eIF-4A, deIF4A, eukaryotic initiation factor 4A, anon26A, l(2)gdh-4, eiF4A, eif-4a, translation initiation factor 4A, 9075, eIF4a, eif4A, l(2)k01501, EIF4A, eIF4A-I, unnamed, CG9075, eukaryotic translation initiation factor 4A, eIF4AI, Eukaryotic initiation factor 4A, l(2)02439, l(2L)162, pecan, eIF 4A, anon-26Aa, Eif-4a, eIF4A, 2439, EIF-4A" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site" CG9075 16-Dec-15 2015_12 "ENSDARG00000040268(eif4a1a),ENSDARG00000003032(eif4a1b),ENSDARG00000016477(eif4a2)" "YJL138C(TIF2),YKR059W(TIF1)" WBGene00002083(inf-1) ENSXETG00000020123(eif4a1) "ENSMUSG00000022884(Eif4a2),ENSMUSG00000059796(Eif4a1)" "ENSG00000156976(EIF4A2),ENSG00000161960(EIF4A1)" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,mitotic cell cycle defective,partially lethal - majority die,decreased cell number,germline clone,developmental rate defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "female germline stem cell,germline clone,intersegmental nerve,anterior fascicle & synapse,embryonic/larval salivary gland,wing disc,amnioserosa,eye,egg chamber,oocyte,centrosome | germline clone,head,cuticle,parasegment 1,parasegment 2,parasegment 3,parasegment 4,parasegment 5,parasegment 6,parasegment 7,parasegment 8,parasegment 9,parasegment 10,parasegment 11,parasegment 12,parasegment 13,parasegment 14,parasegment 15,cephalopharyngeal skeleton,embryonic/first instar larval cuticle" DRSC03526 IEK -1.723586074 -1.691496907 -6.041652709 -6.557148602 1.8586471 1.051560475 FBgn0001404 egh egghead http://flybase.net/reports/FBgn0001404.html protein_coding_gene "0019187=beta-1,4-mannosyltransferase activity" "0001744=optic lobe placode formation, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0016333=morphogenesis of follicular epithelium, 0042248=maintenance of polarity of follicular epithelium, 0048477=oogenesis, 0007299=ovarian follicle cell-cell adhesion, 0016325=oocyte microtubule cytoskeleton organization, 0007281=germ cell development, 0046662=regulation of oviposition, 0007293=germarium-derived egg chamber formation, 0045165=cell fate commitment, 0048935=peripheral nervous system neuron development, 0033227=dsRNA transport, 0030707=ovarian follicle cell development, 0008049=male courtship behavior, 0007411=axon guidance, 0007298=border follicle cell migration, 0045434=negative regulation of female receptivity, post-mating" 0005887=integral component of plasma membrane "Egghead, Egh, EG:BACR25B3.8, l(1)zw4, beta1,4ManT, CG9659, l(1)3Ae, zw-4, zw4, ZW-4, zeste-white 4" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR027389=Beta-1,4-mannosyltransferase Bre-3/Egh" CG9659 16-Dec-15 2015_12 WBGene00000268(bre-3) " adult stage | female && oogenesis stage , embryonic stage | 0-2 hr , adult stage && oogenesis stage | stage S10 " " germarium region 2a && germline cell

, nurse cell

, germarium region 2b && germline cell

" "viable,female sterile,behavior defective,courtship behavior defective,male,partially lethal - majority die,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,germline clone,maternal effect,neurogenic phenotype,neuroanatomy defective,hyperplasia,lethal - all die before end of P-stage,some die during pharate adult stage,visible,heat sensitive" "ovary,eye,germline cell,oocyte,precursor,nurse cell,first optic chiasma,photoreceptor cell,ventral nerve cord,macrochaeta,dorsal appendage,germline clone,presumptive embryonic/larval nervous system,follicle cell,basal stalk,embryonic/larval midgut,nervous system,egg chamber,maternal effect,egg,female reproductive system,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina plexus,embryonic/larval peripheral nervous system,larval abdominal segment 9,plasmatocyte,ectopic,subperineurial glial cell,supernumerary,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,wing vein,embryonic/larval optic neuropil,lamina anlage,lobula,lamina anlage glial cell,lobula & neuron,somatic clone,denticle belt,procephalic segment" DRSC18771 I 2.854196427 0.311087233 0.664995989 -0.85816519 0.366931916 0.264136253 FBgn0003896 tup tailup http://flybase.net/reports/FBgn0003896.html "FBgn0002017, FBgn0015395" protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0001102=RNA polymerase II activating transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0008270=zinc ion binding" "0008407=chaeta morphogenesis, 0007362=terminal region determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0070983=dendrite guidance, 0008045=motor neuron axon guidance, 0007411=axon guidance, 0035310=notum cell fate specification, 0008293=torso signaling pathway, 0043433=negative regulation of sequence-specific DNA binding transcription factor activity, 0022416=chaeta development, 0007390=germ-band shortening, 0046665=amnioserosa maintenance, 0048542=lymph gland development, 0007507=heart development, 0007391=dorsal closure, 0008258=head involution, 0007521=muscle cell fate determination, 0010468=regulation of gene expression" 0005634=nucleus "l(2)E41, CG10619, l(2)37Aa, Isl, tup, Tail-up, lethal(2)37Aa, isl, tail-up, Tup, Islet, islet, dIslet, tailup/islet, Islet 1" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001781=Zinc finger, LIM-type, IPR001356=Homeobox domain" CG10619 16-Dec-15 2015_12 "ENSDARG00000004023(isl1),ENSDARG00000003971(isl2a),ENSDARG00000053499(isl2b)" "YDR379W(RGA2),YOR127W(RGA1)" WBGene00002989(lim-7) ENSXETG00000015323(ISL2) "ENSMUSG00000042258(Isl1),ENSMUSG00000032318(Isl2)" "ENSG00000016082(ISL1),ENSG00000159556(ISL2)" " embryonic stage | stage 10-16 , embryonic stage | stage >=12 , embryonic stage | stage 10 , embryonic stage | stage 16 " " embryonic/larval dorsal vessel

, embryonic brain | restricted

, amnioserosa

, pharyngeal muscle

, foregut primordium

, ventral nerve cord | restricted

, larval alary muscle

, embryonic/larval pharynx | precursor

" " embryonic stage | stage 16 , embryonic stage | stage 10 , embryonic stage | stage 12 , embryonic stage | stage 10-16 " " pharyngeal muscle

, embryonic/larval pharynx | precursor

, embryonic brain | restricted

, embryonic/larval dorsal vessel

, larval alary muscle

, amnioserosa

, ventral nerve cord | restricted

" "viable,partially lethal - majority die,recessive,visible,partially lethal - majority live,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,somatic clone,lethal,partially,neurophysiology defective" "dorsocentral bristle,supernumerary,scutellar bristle,external sensory organ precursor cell,extended germ band embryo,amnioserosa,dorsal closure embryo,embryonic head,cephalopharyngeal skeleton,dorsal bridge,vertical bridge,embryonic/first instar larval cuticle,dorsal,adult antennal lobe projection neuron DL1 adPN,adult antennal lobe projection neuron VM7 adPN,adult antennal lobe projection neuron VA3 adPN,adult antennal lobe projection neuron VM2 adPN,adult antennal lobe projection neuron DM6 adPN,adult antennal lobe projection neuron VA1v adPN,antennal lobe glomerulus DL1,antennal lobe glomerulus VM7,antennal lobe glomerulus VA3,antennal lobe glomerulus VM2,antennal lobe glomerulus DM6,adult antennal lobe projection neuron VA7m lPN,adult antennal lobe projection neuron VA5 lPN,antennal lobe glomerulus VA5,adult antennal lobe projection neuron DM5 lPN,antennal lobe glomerulus DM5,adult antennal lobe projection neuron DM2 lPN,antennal lobe glomerulus DM2,adult antennal lobe projection neuron DM1 lPN,antennal lobe glomerulus DM1,subesophageal ganglion,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1v,intrinsic neuron,interneuron,motor neuron,bipolar dendrite neuron,serotonergic neuron,dopaminergic neuron,intersegmental nerve,transverse nerve,somatic clone,adult cuticle,scutum,scutellum,wing disc,metathoracic laterotergite,sensillum campaniformium,ectopic,mesothoracic tergum,wing sclerite,tegula,macrochaeta,sensillum trichodeum,wing,thorax,interneuron | embryonic stage,motor neuron | embryonic stage,tarsal segment 4,femur,tibia,unguis,metatarsus,mesothoracic pleurum,A1-7 dorsal acute muscle 3,A1-7 dorsal acute muscle 2,eye,mesothoracic bristle" FBgn0052179 Krn Keren http://flybase.net/reports/FBgn0052179.html "FBgn0036744, FBgn0041151, FBgn0064124" protein_coding_gene "0005154=epidermal growth factor receptor binding, 0008083=growth factor activity" "0008355=olfactory learning, 0045741=positive regulation of epidermal growth factor-activated receptor activity, 0007298=border follicle cell migration, 0007173=epidermal growth factor receptor signaling pathway, 0016318=ommatidial rotation, 0008284=positive regulation of cell proliferation, 0048749=compound eye development, 0000165=MAPK cascade, 0042058=regulation of epidermal growth factor receptor signaling pathway" "0005886=plasma membrane, 0005783=endoplasmic reticulum" "spitz2, keren/spitz2, CG32179, krn, s-krn, CG8056, spitz-2, Spitz2, Ker, gritz, skrn, keren, CT19073" "IPR000742=EGF-like domain, IPR013032=EGF-like, conserved site" CG32179 16-Dec-15 2015_12 "partially lethal - majority die,lethal,increased cell number,mitotic cell cycle defective,cell polarity defective,viable,fertile,some die during pupal stage,learning defective,RU486 conditional" "embryonic/larval hemocyte | third instar larval stage,midgut,wing,dorsal appendage,ectopic,denticle belt,cephalopharyngeal skeleton,adult midgut precursor cell | third instar larval stage,enterocyte,midgut interstitial cell,intestinal stem cell,wing vein,denticle,border follicle cell,somatic clone,eye,ommatidium,adult midgut precursor cell,cone cell,supernumerary" DRSC11202 IK -0.154430958 -1.878950925 0.504463465 0.461148564 1.540496675 -0.220926733 FBgn0038067 CG11598 http://flybase.net/reports/FBgn0038067.html protein_coding_gene "0016298=lipase activity, 0004806=triglyceride lipase activity" "0006629=lipid metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG11598 16-Dec-15 2015_12 YKL140W(TGL1) "viable,fertile" DRSC14331 EK -0.839313893 0.381968466 1.902366818 0.142274934 -1.185616628 -2.018548395 FBgn0003328 scb scab http://flybase.net/reports/FBgn0003328.html "FBgn0010481, FBgn0011707, FBgn0013742, FBgn0014404, FBgn0041840" protein_coding_gene "0004872=receptor activity, 0046982=protein heterodimerization activity, 0050839=cell adhesion molecule binding, 0005055=laminin receptor activity" "0007507=heart development, 0003344=pericardium morphogenesis, 0016340=calcium-dependent cell-matrix adhesion, 0040011=locomotion, 0007391=dorsal closure, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0001555=oocyte growth, 0007614=short-term memory, 0007494=midgut development, 0007431=salivary gland development, 0008355=olfactory learning, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0007613=memory, 0033627=cell adhesion mediated by integrin, 0007411=axon guidance, 0007611=learning or memory, 0016477=cell migration, 0043277=apoptotic cell clearance, 0007508=larval heart development, 0042060=wound healing, 0007155=cell adhesion, 0030336=negative regulation of cell migration, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0048149=behavioral response to ethanol, 0007160=cell-matrix adhesion, 0006909=phagocytosis, 0035001=dorsal trunk growth, open tracheal system, 0007424=open tracheal system development" "0005737=cytoplasm, 0008305=integrin complex, 0016021=integral component of membrane, 0009925=basal plasma membrane, 0005886=plasma membrane, 0016324=apical plasma membrane, 0005925=focal adhesion" "CT21280, Vol, aVolado, integrin alphaPS3 subunit, CG8095, alphaInt3, alpha Position-Specific antigen 3, Integrin alphaPS3 subunit, Complementation group 2.11, E(sev-cycE)[e93], Volado, Scab, CT36929, aPS3, alpha[[PS3]], beta[[PS3], l(2)01288, Dm0620, beta[[PS3]]integrin, E(Sev-CycE)E93, alphaPS3 integrin, vol, alphaPS3, volado, alpha-PS3, PS3, ItgaPS3, scab, alphaPS3 subunit" "IPR013519=Integrin alpha beta-propellor, IPR000413=Integrin alpha chain, IPR013649=Integrin alpha-2, IPR018184=Integrin alpha chain, C-terminal cytoplasmic region, conserved site" CG8095 16-Dec-15 2015_12 " embryonic stage | late , embryonic stage | stage 16 , embryonic stage -- adult stage , embryonic stage | stage 8-14 , embryonic stage | stage 13-17 , embryonic stage | stage 9 , embryonic stage | stage 11 , embryonic stage | stage 15-17 , embryonic stage && pupal stage && adult stage , embryonic stage | stage 15 , embryonic stage | early , embryonic stage | stage 11-15 , embryonic stage | stage 7 , embryonic stage | stage 15,16 " " gastric caecum

, midgut constriction

, amnioserosa

, embryonic/larval salivary gland

, visceral mesoderm | presumptive

, tracheal pit

, posterior midgut proper primordium

, embryonic/larval anterior spiracle

, embryonic/larval transverse connective

, antenno-maxillary complex

, anterior midgut proper primordium

, ventral nerve cord | restricted

, embryonic/larval proventriculus

, embryonic/larval dorsal vessel

,

ubiquitous , embryonic salivary gland

, embryonic/larval salivary gland duct

, embryonic/larval dorsal trunk

, amnioproctodeal invagination

, embryonic/larval midgut

, mesectoderm

" adult stage " mushroom body alpha-lobe

, mushroom body gamma-lobe

, mushroom body beta-lobe

, mushroom body

, cell body &&of mushroom body

, calyx of mushroom body

, ellipsoid body

" "partially lethal - majority die,lethal,recessive,viable,fertile,learning defective,memory defective,dominant,neurophysiology defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal - all die before end of larval stage,some die during larval stage,semidominant,visible,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,hyperactive,conditional,chemical resistant" "embryonic/larval hemocyte | third instar larval stage,embryonic dorsal epidermis,dorsal closure embryo,anterior fascicle & synapse,intersegmental nerve,extended germ band embryo,pericardial cell,dorsal superficial trachea,embryonic/larval salivary gland,fascicle,embryo,dorsal,neuromuscular junction,bouton,supernumerary,axon terminus | supernumerary,germline clone,germ band,embryonic heart cardioblast,embryonic/first instar larval cuticle,wing vein,somatic clone,amnioserosa,tracheal branch primordium,cell leading edge,filamentous actin,stage 13 embryo,stage 14 embryo,stage 15 embryo,embryonic hemocyte" FBgn0025641 DAAM Dishevelled Associated Activator of Morphogenesis http://flybase.net/reports/FBgn0025641.html FBgn0027752 protein_coding_gene "0003779=actin binding, 0017048=Rho GTPase binding" "0030838=positive regulation of actin filament polymerization, 0051491=positive regulation of filopodium assembly, 0007424=open tracheal system development, 0007411=axon guidance, 0071689=muscle thin filament assembly, 0048675=axon extension, 0030036=actin cytoskeleton organization, 0051489=regulation of filopodium assembly, 0035017=cuticle pattern formation, 0035152=regulation of tube architecture, open tracheal system, 0060298=positive regulation of sarcomere organization, 0016319=mushroom body development, 0050770=regulation of axonogenesis, 0051017=actin filament bundle assembly" "0005865=striated muscle thin filament, 0016528=sarcoplasm, 0044295=axonal growth cone, 0030018=Z disc" "dDaam, EG:114D9.2, Dishevelled associated activator of morphogenesis, daam, Formin, DIA-like, dDAAM, CG14622, anon-EST:Posey148, Daam, unnamed" "IPR016024=Armadillo-type fold, IPR014767=Diaphanous autoregulatory (DAD) domain, IPR010472=Formin, FH3 domain, IPR014768=Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425=Formin, FH2 domain, IPR010473=Formin, GTPase-binding domain" CG14622 16-Dec-15 2015_12 "ENSDARG00000015059(daam1a),ENSDARG00000009689(daam1b)" YNL271C(BNI1) WBGene00018976(daam-1) ENSXETG00000017030(DAAM1) "ENSMUSG00000034574(Daam1),ENSMUSG00000040260(Daam2)" "ENSG00000100592(DAAM1),ENSG00000146122(DAAM2)" "neuroanatomy defective,viable,lethal - all die before end of larval stage,some die during larval stage,flightless,fertile,locomotor behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,partially lethal - majority die" "ventral nerve cord,neurite,axon,taenidial fold,embryonic/larval tracheal system,indirect flight muscle,myofibril, with DAAMEx1, Dcr-2UAS.cDa, UH3,striated muscle thin filament, with DAAMEx1, Dcr-2UAS.cDa, UH3,striated muscle myosin thick filament, with DAAMEx1, Dcr-2UAS.cDa, UH3,sarcomere, with DAAMEx1, Dcr-2UAS.cDa, UH3,M band, with DAAMEx1, Dcr-2UAS.cDa, UH3,Z disc, with DAAMEx1, Dcr-2UAS.cDa, UH3,embryonic/larval somatic muscle | late third instar larval stage,A1-7 ventral longitudinal muscle 3 | late third instar larval stage,sarcomere | late third instar larval stageMef2.PU,filamentous actin & tracheal fusion cell, with DAAMC.UAS.PT, btl.PS,filamentous actin & tracheal fusion cell, with DAAMUAS.PT.cMa, btl.PS,filamentous actin & tracheal fusion cellbtl.PS,filamentous actin & tracheolar cellbtl.PS,neuropil | embryonic stage,fascicle | embryonic stage,commissure | embryonic stage,myofibril,sarcomere,embryonic/larval trachea,neuropil,fascicle,connective,lateral longitudinal fascicle,embryo,filopodium,myofibril, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,striated muscle thin filament, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,striated muscle myosin thick filament, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,sarcomere, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,M band, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,Z disc, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,embryonic/larval somatic muscle,A1-7 ventral longitudinal muscle 3,sarcomere | late third instar larval stage,filamentous actin,embryonic/larval cuticle" FBgn0002914 Myb Myb oncogene-like http://flybase.net/reports/FBgn0002914.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0007030=Golgi organization, 0007088=regulation of mitotic nuclear division, 0008284=positive regulation of cell proliferation, 0007051=spindle organization, 0007099=centriole replication, 0010971=positive regulation of G2/M transition of mitotic cell cycle, 0000281=mitotic cytokinesis, 0008283=cell proliferation, 0045792=negative regulation of cell size, 0051297=centrosome organization, 0007098=centrosome cycle, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0030261=chromosome condensation, 0000278=mitotic cell cycle, 0006355=regulation of transcription, DNA-templated, 0090282=positive regulation of transcription involved in G2/M transition of mitotic cell cycle, 0090307=mitotic spindle assembly, 0045931=positive regulation of mitotic cell cycle, 0007307=eggshell chorion gene amplification" "0005634=nucleus, 0031523=Myb complex, 0005700=polytene chromosome, 0005719=nuclear euchromatin" "dmyb, Dm Myb, dMyb, MYB, p85, D-myb, DmMyb, Dmyb, DMyb, CG9045, Dm-Myb, dmMYB, DmMYB, c-myb, myb, l(1)XVI, c-Myb, Dm-myb, Dm myb" "IPR017930=Myb domain, IPR015395=C-myb, C-terminal, IPR009057=Homeodomain-like, IPR017877=Myb-like domain, IPR001005=SANT/Myb domain" CG9045 16-Dec-15 2015_12 "ENSDARG00000030999(mybl1),ENSDARG00000053666(cmyb)" YKR099W(BAS1) "ENSXETG00000003725(myb),ENSXETG00000012125(MYBL2)" "ENSMUSG00000019982(Myb),ENSMUSG00000025912(Mybl1),ENSMUSG00000017861(Mybl2)" "ENSG00000118513(MYB),ENSG00000185697(MYBL1),ENSG00000101057(MYBL2)" " embryonic stage | early , pupal stage | early , pupal stage , larval stage | third instar , adult stage && oogenesis stage , adult stage , embryonic stage | late , pupal stage--adult stage " " thoracico-abdominal ganglion

, nervous system

, ovary

, imaginal disc

, brain

, testis

, oocyte

, adult brain

, nurse cell

, embryonic central nervous system

, ventral nerve cord

" "visible,wild-type,dominant,mitotic cell cycle defective,increased cell death,lethal,recessive,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,maternal effect,cytokinesis defective,cell cycle defective,viable" "adult cuticle,eye,ommatidium,eye photoreceptor cell,eye disc,rhabdomere,histoblast,abdomen,cell cyclesd72a),mitotic prophasesd72a),centrosomesd72a),mitosis & nuclear chromosomesd72a),mitotic cell cyclesd72a),wing hair,microchaeta & adult abdomen,cell cycle,mitotic prophase,centrosome,mitosis & nuclear chromosome,mitotic cell cycle,wing,ectopic,macrochaeta,adult abdominal segment,wing & nucleus,wing & cell,precursor,supernumerary,nuclear chromosome,embryo,microchaeta,wing sensillum,adult abdominal sensillum,wing vein,wing & macrochaeta,maternal effect,adult abdomen,microchaeta & wing | maternal effect,macrochaeta & wing | maternal effect,G2 phase,mitotic M phase,S phase,mitotic anaphase,spindle,crystal cell,plasmatocyte,hemocyte & nucleus,embryonic/larval lymph gland,dorsal appendage,somatic clone,chorion | somatic clone,neuroblast,chromosome,condensed nuclear chromosome,wing disc,haltere disc,mitotic cell cycleen-e16E,mitotic cell cyclesd-SG29.1,embryonic/larval salivary gland,mitotic cell cyclefkh.PB,ventral thoracic disc" DRSC20260 IE 2.662936411 -1.332375036 2.493257326 -2.809530054 0.927742074 0.957135508 FBgn0005775 Con Connectin http://flybase.net/reports/FBgn0005775.html FBgn0004358 protein_coding_gene "0007155=cell adhesion, 0007413=axonal fasciculation, 0016200=synaptic target attraction, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" "0031594=neuromuscular junction, 0005886=plasma membrane, 0009986=cell surface, 0044295=axonal growth cone" "transcript-35, conn, anon-64C, CG7503, connectin, Ubx-t35, con, CT1840, CON" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal" CG7503 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage 11-14 , embryonic stage | stage 11-17 , embryonic stage | stage 10 " " visceral mesoderm

, abdominal 1--7 dorsal transverse muscle 1

, abdominal 1--7 lateral transverse muscle 2

, neuron

, somatic muscle

, abdominal 1--7 lateral transverse muscle 1

, larval sense organ &&of embryonic gnathal segment

, somatic mesoderm

, abdominal 1--7 lateral transverse muscle 3

, abdominal 1--7 lateral oblique muscle 1

, embryonic central nervous system | presumptive

, embryonic central nervous system | restricted

, visceral mesoderm | presumptive

, abdominal 1--7 lateral transverse muscle 4

, abdominal 1--7 ventral acute muscle 2

, abdominal 1 ventral acute muscle 3

" " embryonic stage , embryonic stage | late " " myoblast

, anterior commissure

, RP1 neuron

, abdominal 1--7 lateral transverse muscle 3

, interface glial cell

, muscle founder cell

, visceral mesoderm

, abdominal 1 ventral acute muscle 3

, abdominal 1--7 dorsal transverse muscle 1

, peripheral glial cell 4

, larval muscle system

, abdominal 1--7 lateral transverse muscle 1

, abdominal 1--7 lateral transverse muscle 2

, abdominal 1--7 ventral acute muscle 2

, peripheral glial cell 3

, posterior commissure

, neuron

, longitudinal connective

, abdominal 1--7 lateral oblique muscle 1

, motor neuron

, abdominal 1--7 lateral transverse muscle 4

, midline glial cell

, VUM neuron

, peripheral glial cell 1

" "viable,female fertile,male fertile,neuroanatomy defective" "RP1 motor neuron,RP3 motor neuron,abdominal segmental nerve,abdominal ventral muscle,abdominal 1 ventral oblique muscle 4,abdominal 2 ventral oblique muscle 4,abdominal 3 ventral oblique muscle 4,abdominal 4 ventral oblique muscle 4,abdominal 5 ventral oblique muscle 4,abdominal 6 ventral oblique muscle 4,abdominal 7 ventral oblique muscle 4,abdominal 1 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 5,abdominal 3 ventral oblique muscle 5,abdominal 4 ventral oblique muscle 5,abdominal 5 ventral oblique muscle 5,abdominal 6 ventral oblique muscle 5,abdominal 7 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 6,abdominal 3 ventral oblique muscle 6,abdominal 4 ventral oblique muscle 6,abdominal 5 ventral oblique muscle 6,abdominal 6 ventral oblique muscle 6,abdominal 7 ventral oblique muscle 6,abdominal 1 ventral longitudinal muscle 1,abdominal 2 ventral longitudinal muscle 1,abdominal 3 ventral longitudinal muscle 1,abdominal 4 ventral longitudinal muscle 1,abdominal 5 ventral longitudinal muscle 1,abdominal 6 ventral longitudinal muscle 1,abdominal 7 ventral longitudinal muscle 1,abdominal 1 ventral longitudinal muscle 2,abdominal 2 ventral longitudinal muscle 2,abdominal 3 ventral longitudinal muscle 2,abdominal 4 ventral longitudinal muscle 2,abdominal 5 ventral longitudinal muscle 2,abdominal 6 ventral longitudinal muscle 2,abdominal 7 ventral longitudinal muscle 2" FBgn0000139 ash2 "absent, small, or homeotic discs 2" http://flybase.net/reports/FBgn0000139.html FBgn0060470 protein_coding_gene 0008270=zinc ion binding "0048096=chromatin-mediated maintenance of transcription, 0007476=imaginal disc-derived wing morphogenesis, 0007474=imaginal disc-derived wing vein specification, 0048813=dendrite morphogenesis, 0051568=histone H3-K4 methylation" "0048188=Set1C/COMPASS complex, 0005634=nucleus, 0005700=polytene chromosome, 0044666=MLL3/4 complex, 0044665=MLL1/2 complex" "703, CG6677, absent small or homeotic discs 2, ASH2, l(3)SG65, absent, small or homeotic discs 2, many abnormal discs, 1124/11, Ash2, 291.8, l(3)112411, mad, ash-2, l(3)S112411" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR003877=SPRY domain, IPR019786=Zinc finger, PHD-type, conserved site, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001870=B30.2/SPRY domain, IPR001965=Zinc finger, PHD-type" CG6677 16-Dec-15 2015_12 ENSDARG00000060392(ash2l) WBGene00012458(ash-2) ENSXETG00000009007(ASH2L) ENSMUSG00000031575(Ash2l) ENSG00000129691(ASH2L) embryonic stage -- adult stage " larval stage | late , larval stage | third instar , larval stage--pupal stage " " embryonic/larval fat body

, embryonic/larval salivary gland

, imaginal disc

" "lethal,recessive,neuroanatomy defective,partially lethal - majority die,sterile,visible,some die during pharate adult stage,some die during immature adult stage,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of prepupal stage,some die during prepupal stage,viable" "anterior fascicle & synapse,intersegmental nerve,adult mesothoracic segment,ectopic,adult prothoracic segment,wing,crossvein,wing margin,posterior,wing vein L3,wing vein L2,wing vein L5,wing vein,wing disc,wing margin bristle,wing & macrochaetaash18),macrochaeta,wing & macrochaeta,socket,thorax & macrochaetaash18),thorax & macrochaeta,proboscis,antenna,prothoracic segment,dorsal,prothoracic leg,haltere,metathoracic leg,genitalia,somatic clone,wing vein L1,wing vein L6,imaginal disc,wing cell,wing & sensillum campaniformium,capitellum & macrochaeta,capitellum,haltere pedicel,bellum,wing & sensillum campaniformiumash18),dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0003396 shn schnurri http://flybase.net/reports/FBgn0003396.html "FBgn0010584, FBgn0013727, FBgn0043359" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0001105=RNA polymerase II transcription coactivator activity, 0001102=RNA polymerase II activating transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" "0001745=compound eye morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0045705=negative regulation of salivary gland boundary specification, 0048100=wing disc anterior/posterior pattern formation, 0008285=negative regulation of cell proliferation, 0007443=Malpighian tubule morphogenesis, 0008283=cell proliferation, 0007476=imaginal disc-derived wing morphogenesis, 0007398=ectoderm development, 0007494=midgut development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007391=dorsal closure, 0008355=olfactory learning, 0048813=dendrite morphogenesis, 0007422=peripheral nervous system development, 0007179=transforming growth factor beta receptor signaling pathway, 0007611=learning or memory, 0008586=imaginal disc-derived wing vein morphogenesis, 0048190=wing disc dorsal/ventral pattern formation" 0005634=nucleus "schnurri, BEST:SD06302, Schnurri, EP2359, Shn, quo, l(2)04738, quo vadis, umnitza, CG7734, SD06302, EP(2)2359, SHN" "IPR007087=Zinc finger, C2H2, IPR003604=Zinc finger, U1-type, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG7734 16-Dec-15 2015_12 "ENSDARG00000039987(si:ch211-157m21.1),ENSDARG00000018773,ENSDARG00000037154" WBGene00004862(sma-9) ENSXETG00000015441(HIVEP1) "ENSMUSG00000028634(Hivep3),ENSMUSG00000015501(Hivep2),ENSMUSG00000021366(Hivep1)" "ENSG00000127124(HIVEP3),ENSG00000010818(HIVEP2),ENSG00000095951(HIVEP1)" " embryonic stage | stage 8-10 , embryonic stage | stage 14 , larval stage , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage 7-10 , embryonic stage | early , embryonic stage | stage >12 , embryonic stage | blastoderm , embryonic stage | cellular blastoderm , adult stage && oogenesis stage , embryonic stage | stage 10-12 , embryonic stage | stage 4,5 " " ectoderm | dorsal

, embryonic/larval pharynx

, imaginal disc

, parasegment 7 &&of endoderm

, mesoderm | presumptive

, mesoderm

,

ubiquitous , endoderm

,

dorsal , posterior embryonic/larval midgut

, visceral mesoderm &&of parasegment 6,7

, anterior embryonic/larval midgut

, gastric caecum

, nurse cell

, parasegment 4 &&of endoderm

, ovary

, endoderm &&of embryonic/larval midgut

, germarium

" embryonic stage | stage 14 " endoderm

, embryonic/larval foregut

" "circadian rhythm defective,heat sensitive,memory defective,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,cytokinesis defective,viable" "scutellar bristle,eye,ommatidium,wing vein,embryonic epidermis,dorsal,female germline stem cell,germline clone,embryonic head,embryonic/first instar larval cuticle,denticle belt,embryo,filzkorper,embryonic dorsal epidermis,chordotonal organ,lateral,dorsal abdominal cluster,lateral abdominal cluster,presumptive embryonic/larval peripheral nervous system,fascicle,anterior fascicle & synapse,dorsal closure embryo,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,triple row,cell autonomous,somatic clone,double row,ectopic,cell non-autonomous,wing,anterior compartment,epidermis,germline cell,visceral mesoderm,Malpighian tubule,embryonic/larval midgut,midgut constriction,crystal cell,photoreceptor cell" DRSC07681 I -0.715378 -4.10910016 -1.138221484 -1.378545711 -0.225993233 -0.094700599 FBgn0000346 comt comatose http://flybase.net/reports/FBgn0000346.html "FBgn0011678, FBgn0030463" protein_coding_gene "0005524=ATP binding, 0032403=protein complex binding, 0016887=ATPase activity" "0048172=regulation of short-term neuronal synaptic plasticity, 0007274=neuromuscular synaptic transmission, 0031629=synaptic vesicle fusion to presynaptic membrane, 0016082=synaptic vesicle priming, 0006888=ER to Golgi vesicle-mediated transport, 0006909=phagocytosis, 1900073=regulation of neuromuscular synaptic transmission, 0007269=neurotransmitter secretion, 0035494=SNARE complex disassembly, 0007030=Golgi organization" "0008021=synaptic vesicle, 0098527=neuromuscular junction of somatic muscle, 0043195=terminal bouton, 0005737=cytoplasm" "dNSF, com, dNSF-1, dnsf1, DmNSF, CG 1618, NSF1, Comt, dNSF1, NSF-1, dNsf1, CG1618, NSF, NEM-sensitive fusion protein, Comatose, Nsf, N-ethylmaleimide-sensitive fusion protein" "IPR029067=CDC48 domain 2-like, IPR009010=Aspartate decarboxylase-like domain, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain, IPR003338=CDC48, N-terminal subdomain, IPR004201=CDC48, domain 2, IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG1618 16-Dec-15 2015_12 "ENSDARG00000007654(nsfa),ENSDARG00000038991(nsfb)" YBR080C(SEC18) WBGene00003818(nsf-1) ENSMUSG00000034187(Nsf) ENSG00000073969(NSF) " embryonic stage | late , adult stage , larval stage " embryonic central nervous system

"paralytic,heat sensitive,recessive,wild-type,neurophysiology defective,mating defective,bang sensitive,visual behavior defective,locomotor behavior defective,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,germline clone,viable,short lived" "central nervous system,Golgi apparatus,Golgi stack | ectopic,embryonic/larval heart,synaptic vesicle | heat sensitive,retina,heat sensitive,dorsal medial muscle,Golgi stack,optic cartridge & synaptic vesicle,synapse,NMJ bouton" DRSC20319 E -0.537857346 0.163499496 0.836398183 -1.544403707 -0.957642723 -0.585018436 FBgn0004606 zfh1 Zn finger homeodomain 1 http://flybase.net/reports/FBgn0004606.html FBgn0010733 protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0046872=metal ion binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0008354=germ cell migration, 0019730=antimicrobial humoral response, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0061321=garland nephrocyte differentiation, 0007399=nervous system development, 0007498=mesoderm development, 0007417=central nervous system development, 0007280=pole cell migration, 0007507=heart development, 0008406=gonad development, 0048542=lymph gland development, 0048103=somatic stem cell division, 0008045=motor neuron axon guidance, 0007516=hemocyte development, 0007517=muscle organ development" 0005634=nucleus "zfl-1, Zinc-finger homeodomain protein 1, zinc finger homeodomain 1, Zfh1, Zn homeodomain 1, zinc finger homeodomain-1, CG1322, ZFH-1, zinc finger homeodomain protein-1, zhf1, Zfh1a, Zinc Finger Homeodomain 1, zinc-finger homeodomain protein 1, zinc-finger homeodomain1, ZFH1, l(3)00865, Zfh-1, zfh-1, zinc-finger homeobox gene" "IPR001356=Homeobox domain, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR007087=Zinc finger, C2H2" CG1322 16-Dec-15 2015_12 "ENSDARG00000013207(zeb1),ENSDARG00000016788(si:ch211-159p3.1),ENSDARG00000062338(zeb2a)" "ENSXETG00000011655(tcf8),ENSXETG00000000237(ZEB2)" "ENSMUSG00000024238(Zeb1),ENSMUSG00000026872(Zeb2)" "ENSG00000148516(ZEB1),ENSG00000169554(ZEB2)" embryonic stage " embryonic/larval somatic muscle

, adult myoblast

, cardioblast

, embryonic/larval dorsal vessel

, larval visceral muscle

, central nervous system | restricted

, gonad

, mesoderm

, pole cell

" " embryonic stage , embryonic stage | stage 15-17 " " pole cell

, aCC neuron

, somatic muscle

, pericardial cell

, VUM neuron

, embryonic/larval dorsal vessel

, RP neuron

, GW neuron

, gonad

, central nervous system | restricted

, lateral ipsisegmental neuron

, cardioblast

, ventral intersegmental neuron

, adult myoblast

, visceral muscle

, mesoderm

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,heat sensitive,wild-type,viable" "intersegmental nerve,abdominal segmental nerve,presumptive embryonic/larval central nervous system,heat sensitive,eye,macrochaeta & thorax | conditional ts,fat body/gonad primordium,gonad,precursor,heart primordium,germline cell,gonadal sheath proper primordium,embryonic/larval dorsal trunk,cyst progenitor cell,somatic clone,embryonic/larval dorsal vessel,embryonic/larval somatic muscle,pericardial cell,embryonic/larval pericardial cell,cardioblast,embryonic/larval lymph gland,hemocyte,embryonic somatic muscle,male,garland cell,A1-7 dorsal oblique muscle 1,A1-7 dorsal acute muscle 1,testis,male germline cell,supernumerary,somatic cell of testis,abdominal posterior fascicle & axon,motor nerve & axons.gcm,EW3 neuron & axoneg-Mz360,EW1 neuron & axoneg-Mz360,EW2 neuron & axoneg-Mz360,dMP2 neuron & axon22B" DRSC17098 IEK -2.342104419 -4.751844855 -2.071328152 -1.321560735 2.288856022 1.20174875 FBgn0036359 CG14105 http://flybase.net/reports/FBgn0036359.html protein_coding_gene "IPR013105=Tetratricopeptide repeat 2, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain" CG14105 16-Dec-15 2015_12 ENSDARG00000011693(zgc:103600) WBGene00009947(F52H3.5) ENSXETG00000021566(BC089712.1) ENSMUSG00000039438(Ttc36) ENSG00000172425(TTC36) viable DRSC10107 K 0.118730039 0.67355585 0.682176596 0.079869305 -0.172132357 -2.216570351 FBgn0039599 intr intrepid http://flybase.net/reports/FBgn0039599.html protein_coding_gene 0004252=serine-type endopeptidase activity "0032504=multicellular organism reproduction, 0046693=sperm storage, 0006508=proteolysis, 0045434=negative regulation of female receptivity, post-mating" "0005576=extracellular region, 0005615=extracellular space" "CG12558, SPH202" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG12558 16-Dec-15 2015_12 "viable,mating behavior defective,female limited,female semi-fertile" seminal receptacle DRSC14528 K -0.118172991 0.370531479 -0.247825348 0.463993985 0.368503487 1.968629209 FBgn0003997 hid head involution defective http://flybase.net/reports/FBgn0003997.html FBgn0010852 protein_coding_gene "0005515=protein binding, 1990525=BIR domain binding, 0031625=ubiquitin protein ligase binding" "0043065=positive regulation of apoptotic process, 0012501=programmed cell death, 2001056=positive regulation of cysteine-type endopeptidase activity, 0008219=cell death, 0016239=positive regulation of macroautophagy, 0043153=entrainment of circadian clock by photoperiod, 0048813=dendrite morphogenesis, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0046620=regulation of organ growth, 0035096=larval midgut cell programmed cell death, 0002165=instar larval or pupal development, 0008258=head involution, 0006915=apoptotic process, 0048800=antennal morphogenesis, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007424=open tracheal system development, 2000685=positive regulation of cellular response to X-ray, 0071480=cellular response to gamma radiation, 0010114=response to red light, 2001272=positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis, 0097190=apoptotic signaling pathway, 0035071=salivary gland cell autophagic cell death, 0009267=cellular response to starvation, 0045476=nurse cell apoptotic process, 0043281=regulation of cysteine-type endopeptidase activity involved in apoptotic process, 0046668=regulation of retinal cell programmed cell death, 0007548=sex differentiation, 0046667=compound eye retinal cell programmed cell death" 0005739=mitochondrion "head involuted, W, wrinkled, head-involution defective, Head involution defective, Wrinkled, Hid1, CG5123, hid1, hid, head involution defective, HID, wrinkler, head involution defective 1, Hid, his, head-involution-defective, Head involuted defective, head involution defect, l(3)05014" CG5123 16-Dec-15 2015_12 embryonic stage | stage 17 midline glial cell

"visible,decreased cell death,increased cell death,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,male,lethal - all die before end of P-stage,some die during P-stage,lethal,cell death defective,somatic clone,thermotaxis behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,locomotor rhythm defective,eclosion rhythm defective,chemical resistant,circadian rhythm defective,circadian behavior defective,RU486 conditional,behavior defective,partially lethal - majority die,some die during larval stage,temperature conditional,feeding behavior defective,courtship behavior defective,lethal - all die before end of larval stage,starvation stress response defective,chemical sensitive,female limited,heat sensitive,cold sensitive,phototaxis defective,locomotor behavior defective,visual behavior defective,size defective,immune response defective,partially lethal - majority live,conditional,flightless,sleep defective,female fertile" "eye disc,eye,ommatidium,embryonic head,dorsal fold,cephalopharyngeal skeleton,dorsal bridge,male terminalia,wing disc,spermatid,arista lateral,ectopic,arista,peptidergic neuron,male genitalia,wing,ommatidial precursor cluster,dorsal closure embryo,embryonic/larval salivary gland,midline glial cell,long arista lateral,gonadal sheath proper primordium,female,follicle cell,somatic clone,nurse cell,follicle cell & nucleus | somatic clone,RU486 conditional,pigment cell,serotonergic neuron,photoreceptor cell R6,photoreceptor cell R5,photoreceptor cell,embryonic/larval trachea,dorsal,neuron | larval stage,temperature conditional,adult oenocyte,dorsal multidendritic neuron ddaC,dendriteppk.1.9,embryonic/larval carpet glial cell,heat sensitive,glial cell,rhabdomere R7,type II bouton | third instar larval stage,type I bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage,hemocyte | larval stage,tracheal metamere 2,cold sensitive,larval LN period neuron,Bolwig nerve,interommatidial bristle,Bolwig organ,pole cell | embryonic stage 16,pole cell | embryonic stage 15,pole cell | embryonic stage 14,plasmatocyte,embryonic/larval lymph gland | larval stage,gustatory receptor neuron,humeral bristle,supernumerary,ventral nerve cord commissure,embryonic hemocyte,spermathecum,chordotonal organ,embryonic brain,head,embryo,thorax,mesothoracic tergum,amnioserosa,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell" DRSC11316 E -0.540455128 -0.212070722 0.638297492 1.847782029 0.806919307 -0.696353126 FBgn0000464 Lar Leukocyte-antigen-related-like http://flybase.net/reports/FBgn0000464.html FBgn0010057 protein_coding_gene "0032093=SAM domain binding, 0005001=transmembrane receptor protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "1903386=negative regulation of homophilic cell adhesion, 0007399=nervous system development, 0001700=embryonic development via the syncytial blastoderm, 0031290=retinal ganglion cell axon guidance, 0051124=synaptic growth at neuromuscular junction, 0048477=oogenesis, 0007155=cell adhesion, 0007283=spermatogenesis, 0008045=motor neuron axon guidance, 0048675=axon extension, 0048841=regulation of axon extension involved in axon guidance, 0006470=protein dephosphorylation, 0007411=axon guidance, 0007412=axon target recognition, 0008594=photoreceptor cell morphogenesis, 0008360=regulation of cell shape, 0045467=R7 cell development" "0005875=microtubule associated complex, 0005925=focal adhesion, 0016021=integral component of membrane, 0030424=axon, 0005886=plasma membrane" "LAR receptor tyrosine phosphatase, CG10443, leukocyte-antigen-related-like, PTP38A, DLar, lar, DLAR, Ptp38A, bypass, LAR, Dlar, Leukocyte-Antigen-Related-Like, leukocyte- antigen-related-like, dlar" "IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR000242=PTP type protein phosphatase, IPR007110=Immunoglobulin-like domain, IPR000387=Tyrosine specific protein phosphatases domain" CG10443 16-Dec-15 2015_12 "ENSDARG00000005754(LOC100330517),ENSDARG00000059452(LOC100330629)" WBGene00004215(ptp-3) "ENSXETG00000011833(PTPRD),ENSXETG00000002257(PTPRF)" "ENSMUSG00000028399(Ptprd),ENSMUSG00000013236(Ptprs),ENSMUSG00000033295(Ptprf)" "ENSG00000153707(PTPRD),ENSG00000105426(PTPRS),ENSG00000142949(PTPRF)" " embryonic stage | stage >=12 , embryonic stage " " commissure

, ventral nerve cord

, embryonic/larval trachea

, longitudinal connective

" "wild-type,optomotor response defective,somatic clone,visual behavior defective,lethal,neurophysiology defective,neuroanatomy defective,recessive,behavior defective,cell autonomous,female sterile,partially lethal - majority die,RU486 conditional,oxidative stress response defective,viable" "egg chamber,polar follicle cell,ectopic,germarium,germarium region 2b,germarium region 3,egg,follicle cell,intersegmental nerve,photoreceptor cell & growth cone | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,abdominal segmental nerve,photoreceptor cell R7,somatic clone,photoreceptor cell R7 & axon,eye disc,NMJ bouton,photoreceptor cell R7 & growth cone,photoreceptor cell R7 & growth cone | somatic clone,optic cartridge,photoreceptor cell,cell autonomous,photoreceptor cell R4,medulla,anterior fascicle & axon | ectopic,bouton,neuromuscular junction,oocyte,dorsal appendage,stage S14 oocyte,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,actin filament & follicle cell | somatic clone | cell non-autonomous,cell non-autonomous,longitudinal connective,intersegmental nerve branch ISNb of A1-7,supernumerary,RU486 conditional,neuromuscular junction | RU486 conditionalelav.Switch.PO,neuromuscular junctionelav.PLu,NMJ bouton | larval stage" FBgn0039140 Miro Mitochondrial Rho http://flybase.net/reports/FBgn0039140.html protein_coding_gene "0005509=calcium ion binding, 0003924=GTPase activity, 0005525=GTP binding, 0000287=magnesium ion binding" "0007268=synaptic transmission, 0048489=synaptic vesicle transport, 0019725=cellular homeostasis, 0051646=mitochondrion localization, 0015031=protein transport, 0047497=mitochondrion transport along microtubule, 0097345=mitochondrial outer membrane permeabilization, 0034643=establishment of mitochondrion localization, microtubule-mediated, 0000226=microtubule cytoskeleton organization, 0031122=cytoplasmic microtubule organization, 0007264=small GTPase mediated signal transduction" 0031307=integral component of mitochondrial outer membrane "CG5410, miro, dMiro, DmMiro, Q8IMX7-2, Q8IMX7-1, B682, dmiro, mitochondrial Rho-GTPase" "IPR002048=EF-hand domain, IPR020860=MIRO domain, IPR003578=Small GTPase superfamily, Rho type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR011992=EF-hand domain pair, IPR020849=Small GTPase superfamily, Ras type, IPR021181=Mitochondrial Rho GTPase, IPR003579=Small GTPase superfamily, Rab type, IPR018247=EF-Hand 1, calcium-binding site, IPR013567=EF hand associated, type-2, IPR013566=EF hand associated, type-1" CG5410 16-Dec-15 2015_12 "ENSDARG00000018130(rhot1a),ENSDARG00000070316(rhot1b)" YAL048C(GEM1) "WBGene00019544(K08F11.5),WBGene00021651(Y47G6A.27)" ENSXETG00000003628(rhot2) "ENSMUSG00000017686(Rhot1),ENSMUSG00000025733(Rhot2)" "ENSG00000126858(RHOT1),ENSG00000140983(RHOT2)" "phototaxis defective,somatic clone,partially lethal - majority die,recessive,locomotor behavior defective,body size defective,neurophysiology defective,some die during pupal stage,neuroanatomy defective" "mitochondrion & motor neuron | larval stageRapGAP1-OK6,mitochondrion & neuron | larval stage,mitochondrion & somatic muscle | larval stage,bouton & neuromuscular junction | larval stage,somatic muscle,microtubule & bouton,mitochondrion,mitochondrion & motor neuron | larval stage,mitochondrion & neuromuscular junction | supernumerary | larval stage,neuron,midline primordium,dendrite,dorsal multidendritic neuron ddaE,mitochondrionrepo.PL, repo,embryonic/larval glial cell,photoreceptor cell,mitochondrionGMR.PF,lamina,adult brain,mitochondrionelav.PU" FBgn0003964 usp ultraspiracle http://flybase.net/reports/FBgn0003964.html protein_coding_gene "0042562=hormone binding, 0008289=lipid binding, 0000976=transcription regulatory region sequence-specific DNA binding, 0003677=DNA binding, 0004884=ecdysteroid hormone receptor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0005500=juvenile hormone binding, 0004879=ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, 0008270=zinc ion binding, 0042803=protein homodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0046982=protein heterodimerization activity" "0045893=positive regulation of transcription, DNA-templated, 0071390=cellular response to ecdysone, 0042594=response to starvation, 0007281=germ cell development, 0016319=mushroom body development, 0045596=negative regulation of cell differentiation, 0040034=regulation of development, heterochronic, 0006697=ecdysone biosynthetic process, 0007552=metamorphosis, 0035073=pupariation, 0016322=neuron remodeling, 0007517=muscle organ development, 0046620=regulation of organ growth, 0045892=negative regulation of transcription, DNA-templated, 0007298=border follicle cell migration, 0043401=steroid hormone mediated signaling pathway, 0035075=response to ecdysone, 0048813=dendrite morphogenesis, 0048666=neuron development" "0030425=dendrite, 0005700=polytene chromosome, 0008230=ecdysone receptor holocomplex, 0008232=activator ecdysone receptor complex, 0005634=nucleus" "Cf1, CF1, DmUsp, 2C, EG:22E5.1, dUSP, DmUSP, CF1/Usp, X receptor at 2C, Usp, XR2C, CG4380, Chorion factor 1, l(1)usp, NR2B4, USP, l(1)2Cf, dmUSP, chorion factor CF1, Ultraspiracle, Ultraspiricle, cf1, CF1/USP" "IPR001723=Nuclear hormone receptor, IPR013088=Zinc finger, NHR/GATA-type, IPR000536=Nuclear hormone receptor, ligand-binding domain, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR000003=Retinoid X receptor/HNF4" CG4380 16-Dec-15 2015_12 "ENSDARG00000057737(rxraa),ENSDARG00000035127(rxrab),ENSDARG00000004697(rxrgb),ENSDARG00000024951,ENSDARG00000002006(rxrbb),ENSDARG00000005593(rxrga)" WBGene00006790(unc-55) "ENSXETG00000012733(RXRA),ENSXETG00000020416(rxrb),ENSXETG00000004750(RXRG)" "ENSMUSG00000015846(Rxra),ENSMUSG00000015843(Rxrg),ENSMUSG00000039656(Rxrb)" "ENSG00000186350(RXRA),ENSG00000143171(RXRG),ENSG00000206218,ENSG00000204231(RXRB),ENSG00000206289" " adult stage && oogenesis stage , embryonic stage | stage 12 , adult stage && oogenesis stage | stage >=S8 , embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage -- adult stage " " follicle cell

, ventral nerve cord

, oocyte

, nurse cell

, embryonic/larval midgut

,

ubiquitous , ovary

" " larval stage | late third instar larval stage , embryonic stage--pupal stage , larval stage | third instar , adult stage && oogenesis stage " " larval central nervous system

, embryonic/larval fat body

, dorsal mesothoracic disc

, antennal disc

, eye disc

, ring gland

, ventral thoracic disc

, nurse cell

, follicle cell

, embryonic/larval salivary gland

" "neuroanatomy defective,hypoactive,touch sensitivity defective,wild-type,lethal,recessive,germline clone,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,maternal effect,lethal - all die during first instar larval stage,lethal - all die during P-stage,partially,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,circadian rhythm defective" "mushroom body gamma-lobe | adult stage,adult mushroom body,embryonic/larval anterior spiracle,imaginal disc,embryonic/larval midgut | embryonic stage,midgut imaginal island,embryonic/larval salivary gland | embryonic stage,egg,germline clone,maternal effect,dorsal appendage,terminal filament,olfactory neuron & axon,olfactory neuron & dendrite,antennal lobe & axon,adult mushroom body & axon,ommatidial precursor cluster,somatic clone,morphogenetic furrow,dorsal mesothoracic disc & neuron | somatic clone,embryo,posterior,dendritic arborizing neuron,gamma-lobe & neuron | somatic clone,rhabdomere,retina,cell non-autonomous,mushroom body gamma-lobe,adult antennal lobe projection neuron,persistent antennal lobe projection neuron,egg chamber,embryonic/first instar larval cuticle,puparium,anterior pupal spiracle,border follicle cell,triple row,ectopic,precursor,ommatidium,female germline cell,supernumerary,heat sensitive,lobe system of adult mushroom body,mushroom body beta-lobe,dendrite109(2)80,dorsal multidendritic neuron ddaC,midgut constriction,embryonic/larval tracheal system" FBgn0266756 btsz bitesize http://flybase.net/reports/FBgn0266756.html "FBgn0038267, FBgn0063267, FBgn0051306, FBgn0038265, FBgn0038264, FBgn0038263, FBgn0010940, FBan0007343, FBpp0082473, FBpp0082472, FBtr0083014, FBtr0083013, FBan0031306, FBgn0053555, FBgn0264754, FBgn0044870" protein_coding_gene "0017137=Rab GTPase binding, 0005215=transporter activity" "0030866=cortical actin cytoskeleton organization, 0007436=larval salivary gland morphogenesis, 0035149=lumen formation, open tracheal system, 0007015=actin filament organization, 0010004=gastrulation involving germ band extension, 0048489=synaptic vesicle transport, 0040018=positive regulation of multicellular organism growth, 0016331=morphogenesis of embryonic epithelium, 0042249=establishment of planar polarity of embryonic epithelium, 0006886=intracellular protein transport, 0045793=positive regulation of cell size, 0043297=apical junction assembly" "0016324=apical plasma membrane, 0016020=membrane" "BcDNA:GH06647, CG18280, Granulophilin, bite size, CG33555, Bitesize, l(3)10418, CG7343, Btsz, CG44012, CG17304, CG31306, CG14858" "IPR010911=Rab-binding domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR001565=Synaptotagmin, IPR000008=C2 domain" CG44012 16-Dec-15 2015_12 DRSC15320 IK 1.532210447 -0.68566855 0.390924927 0.177955209 2.875074787 -0.23369725 FBgn0000017 Abl Abl tyrosine kinase http://flybase.net/reports/FBgn0000017.html "FBgn0024512, FBgn0036649" protein_coding_gene "0004713=protein tyrosine kinase activity, 0004715=non-membrane spanning protein tyrosine kinase activity, 0005524=ATP binding, 0005515=protein binding" "0008045=motor neuron axon guidance, 0003382=epithelial cell morphogenesis, 0003402=planar cell polarity pathway involved in axis elongation, 0008064=regulation of actin polymerization or depolymerization, 0006468=protein phosphorylation, 0002009=morphogenesis of an epithelium, 0001764=neuron migration, 0008360=regulation of cell shape, 0016199=axon midline choice point recognition, 0007370=ventral furrow formation, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0046827=positive regulation of protein export from nucleus, 0031647=regulation of protein stability, 0072499=photoreceptor cell axon guidance, 0048749=compound eye development, 0007419=ventral cord development, 0007391=dorsal closure, 0007303=cytoplasmic transport, nurse cell to oocyte, 0007409=axonogenesis, 0032880=regulation of protein localization, 0007411=axon guidance, 0018108=peptidyl-tyrosine phosphorylation, 0048813=dendrite morphogenesis, 0007417=central nervous system development" "0005938=cell cortex, 0030424=axon, 0005912=adherens junction, 0070938=contractile ring, 0019897=extrinsic component of plasma membrane, 0045179=apical cortex, 0005911=cell-cell junction, 0005737=cytoplasm, 0005829=cytosol, 0005927=muscle tendon junction" "DROTKABL3, Dash, D-abelson, Abelson, abl1, Abelson kinase, CG4032, D-ash, l(3)04674, l(3)c-abl, Dabl, abl kinase, D-abl, Abelson Kinase, cAbl, Abelson tyrosine kinase, DAbl, Ddash/abl, Abelson Tyrosine Kinase, Ableson, C-abl, Abl1, D-Abl, abelson, AblK, Abl, ABL, c-abl, l(3)73Ba, abl, Am ABL, Dsrc7, dAbl, Abl oncogene, 4674" "IPR000980=SH2 domain, IPR017441=Protein kinase, ATP binding site, IPR008266=Tyrosine-protein kinase, active site, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR001452=SH3 domain, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR015015=F-actin binding" CG4032 16-Dec-15 2015_12 "ENSDARG00000013491,ENSDARG00000055672(LOC560932)" WBGene00000018(abl-1) "ENSXETG00000012531(ABL2),ENSXETG00000001464(ABL1)" "ENSMUSG00000026842(Abl1),ENSMUSG00000026596(Abl2)" "ENSG00000143322(ABL2),ENSG00000097007(ABL1)" " prepupal stage--pupal stage , oogenesis stage && adult stage | female , embryonic stage , adult stage | female , adult stage && oogenesis stage " " ovary

, oocyte

" " embryonic stage , embryonic stage | late , embryonic stage | early " " embryonic central nervous system

, epithelial cell

, adepithelial cell

, epithelial cell | apical

, neuron

, imaginal disc

" "lethal,neuroanatomy defective,viable,fertile,recessive,wild-type,partially lethal - majority die,somatic clone,cell migration defective,germline clone,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,reduced,visible,partially lethal - majority live,mitotic cell cycle defective,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,neurophysiology defective,size defective,heat sensitive,cell shape defective" "synaptic vesicle & NMJ bouton,longitudinal connective,presumptive embryonic/larval central nervous system,commissure,embryonic leading edge cell,dorsal closure embryo,extended germ band embryo,amnioserosa,antennal lobe glomerulus,antennal commissure,intersegmental nerve,NMJ bouton,supernumerary,longitudinal connective | embryonic stage,ommatidium,longitudinal connective | embryonic stage 16,embryonic/larval neuron,central nervous system,ventral nerve cord,lamina,somatic clone,RP2 motor neuron,EW neuron,germline clone,maternal effect,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,eye,follicle cell & actin filament | somatic clone,follicle cell,actin cytoskeleton | embryonic stage | maternal effect,interommatidial bristle,eye photoreceptor cell,embryonic/first instar larval cuticle,dorsal,ventral furrow,non-rescuable maternal effect,spindle | cleavage stage | maternal effect,anterior commissure,posterior commissure,egg,actin filament & egg chamber | germ-line clone,ventral nerve cord commissure,embryonic/larval neuromuscular junction,midline crossing tract,heat sensitive,retina,ventral adult lateral neuron & axonP2.4.Pdf" FBgn0000580 eor extra organs http://flybase.net/reports/FBgn0000580.html FBgn0017382 gene "0007444=imaginal disc development, 0010004=gastrulation involving germ band extension" "A7, l(1)17-252, l(1)20Aa, lethal(1)20Af, E54, 12, eo, N-30, lA7, section 17, 17, lN-30, l(1)20Af, section 12, l(1)E-54" 16-Dec-15 2015_12 "lethal,recessive,germline clone,rescuable maternal effect,visible,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "eye,leg,antenna,arista,embryo,germline clone,embryonic/first instar larval cuticle,wing" FBgn0050324 CG30324 http://flybase.net/reports/FBgn0050324.html FBgn0034107 protein_coding_gene CG7750 CG30324 16-Dec-15 2015_12 viable FBgn0028987 Spn28F Serpin 28F http://flybase.net/reports/FBgn0028987.html FBgn0032007 protein_coding_gene "0042562=hormone binding, 0004867=serine-type endopeptidase inhibitor activity" "0032504=multicellular organism reproduction, 0010951=negative regulation of endopeptidase activity, 0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis" "0005615=extracellular space, 0005576=extracellular region" "serpin 2, spn2, sp2, Sp2, CG8137, Spn28F, Serine protease inhibitor 2, Spn2" "IPR023796=Serpin domain, IPR000215=Serpin family" CG8137 16-Dec-15 2015_12 "ENSDARG00000070396(serpinb1l2),ENSDARG00000055416(serpinb1),ENSDARG00000055431,ENSDARG00000057263(zgc:173729),ENSDARG00000059873,ENSDARG00000039849,ENSDARG00000014556" "ENSXETG00000027588(serpinb6),ENSXETG00000027590(BC087996.1),ENSXETG00000025592()" "ENSG00000206073(SERPINB4),ENSG00000057149(SERPINB3),ENSG00000197641(SERPINB13),ENSG00000166634(SERPINB12),ENSG00000166396(SERPINB7),ENSG00000117601(SERPINC1)" lethal FBgn0266260 CR44955 http://flybase.net/reports/FBgn0266260.html non_protein_coding_gene lincRNA.737 CR44955 16-Dec-15 2015_12 FBgn0000135 arth arthritic http://flybase.net/reports/FBgn0000135.html gene l(1)1Ah 16-Dec-15 2015_12 "visible,recessive,uncoordinated" "leg,tarsal segment,unguis" FBgn0038043 CG17202 http://flybase.net/reports/FBgn0038043.html FBgn0062436 protein_coding_gene 0003713=transcription coactivator activity "0006355=regulation of transcription, DNA-templated" 0005634=nucleus BcDNA:RH21090 "IPR026060=Associate of Myc 1, IPR003117=cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG17202 16-Dec-15 2015_12 ENSDARG00000069444 FBgn0001108 DCTN1-p150 "Dynactin 1, p150 subunit" http://flybase.net/reports/FBgn0001108.html protein_coding_gene "0003777=microtubule motor activity, 0045502=dynein binding" "0048477=oogenesis, 0048675=axon extension, 0042052=rhabdomere development, 0051383=kinetochore organization, 0051642=centrosome localization, 0001751=compound eye photoreceptor cell differentiation, 0008090=retrograde axon cargo transport, 0007067=mitotic nuclear division, 0034501=protein localization to kinetochore, 0006886=intracellular protein transport, 0051256=mitotic spindle midzone assembly, 0051225=spindle assembly, 0048491=retrograde synaptic vesicle transport, 0001709=cell fate determination, 0045198=establishment of epithelial cell apical/basal polarity, 0007052=mitotic spindle organization, 0042051=compound eye photoreceptor development, 0016330=second mitotic wave involved in compound eye morphogenesis, 0047497=mitochondrion transport along microtubule, 0007349=cellularization, 0051028=mRNA transport, 0035011=melanotic encapsulation of foreign target, 0051299=centrosome separation, 0022008=neurogenesis, 0001754=eye photoreceptor cell differentiation, 0007018=microtubule-based movement" "0030496=midbody, 0031616=spindle pole centrosome, 0005876=spindle microtubule, 0000776=kinetochore, 0005737=cytoplasm, 0005869=dynactin complex, 0005828=kinetochore microtubule, 0035371=microtubule plus-end, 0005818=aster, 0005813=centrosome, 0005739=mitochondrion" "Glu, P150, t1, p150[Glued], Dynactin P150, Gl, dynactin, p150/Glued, DYNA_DROME, FCP-D, P150[Glued], CG9206, glued, p150/glued, p150glued, p150[glued], p150, p150-Glued, Glued, Dynactin" "IPR000938=CAP Gly-rich domain, IPR027663=Dynactin subunit 1, IPR022157=Dynein associated protein" CG9206 16-Dec-15 2015_12 "ENSDARG00000019743(LOC100333531),ENSDARG00000056753(dctn1b)" YPL174C(NIP100) WBGene00001017(dnc-1) ENSXETG00000011761(Q6GLB3_XENTR) ENSMUSG00000031865(Dctn1) ENSG00000204843(DCTN1) " adult stage && oogenesis stage , embryonic stage&&larval stage&&pupal stage , larval stage | late , egg stage | unfertilized egg , spermatogenesis && adult stage , embryonic stage , adult stage , embryonic stage&&pupal stage " " ovary

, unfertilized egg

, testis

, adult head

" " adult stage && oogenesis stage | stage S9 , oogenesis stage | early , adult stage && oogenesis stage " " oocyte | posterior

, germarium region 2b && oocyte

" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,neuroanatomy defective,neurophysiology defective,viable,sterile,locomotor behavior defective,flightless,short lived,cell shape defective,somatic clone,visible,cell polarity defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,mitotic cell cycle defective,lethal,dominant,eye color defective,fertile,wild-type,heat sensitive,paralytic,female sterile,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,male fertile,lethal - all die before end of larval stage,some die during larval stage,partially,uncoordinated,conditional,proboscis extension reflex defective,progressive,immune response defective" "NMJ bouton,follicle cell,somatic clone,eye,mitochondrionD42,spindleC587,cyst progenitor cell,ommatidium,spindle pole centrosome,spindle,cone cell,nervous system & thorax & pupa,sensory neuron,motor neuron,lipid particle | maternal effect,pigment cell,prothoracic femoral chordotonal organ & axon,mesothoracic femoral chordotonal organ & axon,metathoracic femoral chordotonal organ & axon,sensillum trichodeum & leg & axon,photoreceptor cell,synapse,interommatidial bristle,macrochaeta,eye photoreceptor cell & nucleus,eye photoreceptor cell & microtubule,eye photoreceptor cell,rhabdomere,primary pigment cell,secondary pigment cell,tertiary pigment cell,giant fiber neuron,giant fibers & synapse,mitochondrion,Golgi apparatus,optic lobe,wing,photoreceptor cell R1,photoreceptor cell R6,posterior fascicle & axon,cuticle,synapse & neuromuscular junction,postsynaptic membrane,bouton,giant fibers & nerve terminal,giant fibers & nerve terminalc17,giant fibers & synapsec17,eye disc,morphogenetic furrow,eye photoreceptor cell & nucleusGlass38-1,larval Bolwig's organ & nucleuselav.PLu,embryonic/larval neuron,photoreceptor cell R7,segmental nerve,conditional,synapseRapGAP1-OK6,CSD interneuron,type Ib terminal bouton | third instar larval stageD42,external sensory organ precursor cell I,centrosomeneur-P72,adult neuromuscular junction,proboscis muscle,border follicle cell,ganglion mother cell" DRSC11175 I 2.114087164 0.32034091 -0.62696453 -0.006911854 0.20996873 0.714014678 FBgn0051549 CG31549 http://flybase.net/reports/FBgn0051549.html FBgn0037353 protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process CG11005 "IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG31549 16-Dec-15 2015_12 ENSDARG00000035129(zgc:101858) "YIR035C(),YIR036C(IRC24)" "WBGene00021647(Y47G6A.22),WBGene00021646(Y47G6A.21)" ENSXETG00000026045(BC076694.1) ENSMUSG00000030825(Hsd17b14) ENSG00000087076(HSD17B14) FBgn0033638 CG9005 http://flybase.net/reports/FBgn0033638.html FBgn0063271 protein_coding_gene 0034976=response to endoplasmic reticulum stress BcDNA:GH05710 IPR025261=Domain of unknown function DUF4210 CG9005 16-Dec-15 2015_12 ENSDARG00000040452(si:dkey-266j9.3) ENSXETG00000006354(BC089633.1) ENSMUSG00000034858(BC031353) ENSG00000047346(KIAA1370) "viable,body color defective" mesothoracic tergum FBgn0001237 hup hold up http://flybase.net/reports/FBgn0001237.html gene "0048477=oogenesis, 0007314=oocyte anterior/posterior axis specification, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0016333=morphogenesis of follicular epithelium, 0046843=dorsal appendage formation, 0016325=oocyte microtubule cytoskeleton organization, 0045165=cell fate commitment" hold-up 16-Dec-15 2015_12 "female sterile,recessive,male sterile" "egg,egg chamber,egg chamber & nucleus,dorsal appendage,wing,oocyte,micropyle" FBgn0086208 su(comp)3R-1 http://flybase.net/reports/FBgn0086208.html gene 0040008=regulation of growth 16-Dec-15 2015_12 "hyperplasia,recessive,somatic clone,visible" "wing disc,somatic clone,eye,wing" FBgn0264377 CG43829 http://flybase.net/reports/FBgn0264377.html protein_coding_gene CG43829 16-Dec-15 2015_12 FBgn0040872 CG12694 http://flybase.net/reports/FBgn0040872.html protein_coding_gene 16-Dec-15 2015_12 FBgn0013343 Syx1A Syntaxin 1A http://flybase.net/reports/FBgn0013343.html "FBgn0010900, FBgn0023459, FBgn0039148, FBgn0042210, FBgn0066005" protein_coding_gene "0005515=protein binding, 0005484=SNAP receptor activity, 0000149=SNARE binding" "0042335=cuticle development, 0007274=neuromuscular synaptic transmission, 0007349=cellularization, 0006887=exocytosis, 0016081=synaptic vesicle docking, 0006906=vesicle fusion, 0031629=synaptic vesicle fusion to presynaptic membrane, 0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0017157=regulation of exocytosis, 0007268=synaptic transmission, 0006936=muscle contraction, 0007482=haltere development, 0007317=regulation of pole plasm oskar mRNA localization, 0007269=neurotransmitter secretion, 0000281=mitotic cytokinesis" "0031201=SNARE complex, 0016020=membrane, 0005886=plasma membrane, 0016021=integral component of membrane, 0008021=synaptic vesicle, 0043195=terminal bouton" "syntaxin 1, Dm Syx1, syntaxin1A, SYNTAXIN, Syntaxin1A, syx-1, CG31136/CG33100, syx-1A, Syntaxin, Syt1A, CT30033, CG10716, STX1A, syntaxin 1A, SYX1A, Syx, syntaxin-1, l(3)06737, Syntx 1, syt-1A, dsyntaxin-1A, CG18615, SyxA, DmSyx1A, Syx-1A, anon-WO02059370.54, CG5448, syntaxin, syntaxin-1A, CG31136, Syx1, syntaxin1, Syntaxin 1, Dsyntaxin-1A, anon-EST:Gibbs4, Syntaxin-1A, syx1A, SYX 1A, syx, Syx1a, syx1, dSyx1, SYX, synt, dsyn-1A" "IPR000727=Target SNARE coiled-coil homology domain, IPR006011=Syntaxin, N-terminal domain, IPR006012=Syntaxin/epimorphin, conserved site, IPR010989=t-SNARE, IPR028669=Syntaxin 1" CG31136 16-Dec-15 2015_12 ENSDARG00000000503(syntaxin1b) "YMR183C(SSO2),YPL232W(SSO1)" WBGene00006798(unc-64) ENSXETG00000010345(STX1A) "ENSMUSG00000007207(Stx1a),ENSMUSG00000030806(Stx1b)" "ENSG00000106089(STX1A),ENSG00000099365(STX1B)" " embryonic stage | early , embryonic stage | stage 9 , embryonic stage , embryonic stage -- adult stage " " organism | 0% egg length

, ectoderm

, central nervous system

, embryonic peripheral nervous system

, posterior midgut proper primordium

,

ubiquitous , anterior midgut proper primordium

, neuroblast

, embryonic/larval garland cell

, embryonic neuron

, amnioproctodeal invagination

" " embryonic stage | stage 15-17 , embryonic stage , adult stage , embryonic stage | early , embryonic stage | stage 9 , larval stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-8 " " ectoderm

, neuron

, neuropil

, commissure

, pole bud

, lamina

, embryonic peripheral nervous system

, neuromuscular junction

, central nervous system

, synapse

, longitudinal connective

, germline cyst

, nurse cell

,

ubiquitous , germarium region 3

, medulla

, posterior embryonic/larval midgut

, bouton

, germarium region 2b

, germarium region 2a

, cell body

, anterior embryonic/larval midgut

, adult brain

, ventral neurogenic region

, embryonic/larval garland cell

, mesoderm

" "wild-type,neurophysiology defective,heat sensitive,lethal,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,viable,hypoactive,paralytic,semidominant,visual behavior defective,neuroanatomy defective,uncoordinated,dominant,visible,somatic clone,cytokinesis defective,maternal effect" "neuromuscular junction,eye,ommatidium,somatic muscle,embryonic/first instar larval cuticle,wing,neuromuscular junction | embryonic stage,synapse,denticle,neuromuscular junction | larval stage,embryonic epidermis,embryonic/larval muscle system,synapse | embryonic stage, with Syx1AëÓ229,retina,optic cartridge & synaptic vesicle,eye photoreceptor cell,somatic clone,oocyte,germline clone,longitudinal connective,intersegmental nerve,segmental nerve,mitotic telophase,mitotic telophase & spindle,actomyosin contractile ring,synapse | embryonic stage, with Syx1AA243V.V247A,mouth hooks,denticle belt,embryonic foregut,embryonic/larval midgut primordium,embryonic hindgut,ventral nerve cord,maternal effect,embryonic/larval midgut,egg,embryo,cytoskeleton | embryonic stage | germline clone,nucleus | embryonic stage | germline clone,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0002940 ninaE neither inactivation nor afterpotential E http://flybase.net/reports/FBgn0002940.html FBgn0046298 protein_coding_gene "0004930=G-protein coupled receptor activity, 0008020=G-protein coupled photoreceptor activity, 0005515=protein binding" "0043052=thermotaxis, 0009584=detection of visible light, 0008594=photoreceptor cell morphogenesis, 0008344=adult locomotory behavior, 0046673=negative regulation of compound eye retinal cell programmed cell death, 0042052=rhabdomere development, 0007601=visual perception, 0007186=G-protein coupled receptor signaling pathway, 0071632=optomotor response, 0030265=phospholipase C-activating rhodopsin mediated signaling pathway, 0009589=detection of UV, 0009642=response to light intensity, 0042331=phototaxis, 0007602=phototransduction" "0005767=secondary lysosome, 0016028=rhabdomere, 0016023=cytoplasmic membrane-bounded vesicle, 0005886=plasma membrane, 0016027=inaD signaling complex, 0097038=perinuclear endoplasmic reticulum, 0005771=multivesicular body, 0016021=integral component of membrane, 0016029=subrhabdomeral cisterna, 0005791=rough endoplasmic reticulum" "Rh1/ninaE, rh1, DmRh1, DMELRH1, NinaE, 143283_at, opsin, Neither inactivation nor afterpotential E, BEST:GH11778, rhodopsin1, rh1/ninaE, CG4550, Rhodopsin-1, Dm Rh1, Rhodopsin1, RH1, 1F9, ora, Rhodopsin 1, Nina E, Rh1, Rh-1, rhodopsin 1, rhodopsin, Rh1(ninaE), DRh1, Rh, R, rhodopsin-1, FBgn0002940, Rhodopsin" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR001735=Opsin RH1/RH2, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR001760=Opsin, IPR027430=Visual pigments (opsins) retinal binding site" CG4550 16-Dec-15 2015_12 "ENSDARG00000007553(opn4l),ENSDARG00000053929(LOC566133),ENSDARG00000022098(opn4a),ENSDARG00000051908(si:dkeyp-100d11.3)" ENSXETG00000019216(OPN4) ENSMUSG00000021799(Opn4) ENSG00000122375(OPN4) " adult stage , larval stage " " eye

, adult head

, Bolwig's organ

" "neurophysiology defective,stress response defective,phototaxis defective,increased cell death,neuroanatomy defective,thermotaxis behavior defective,size defective,visual behavior defective,dominant,wild-type,recessive,temperature conditional,optomotor response defective,behavior defective,locomotor behavior defective,viable,visible" "rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere membrane,ommatidium,rhabdomere of eye photoreceptor cell,endoplasmic reticulum, with ninaE17,mitochondrion, with ninaE17,autophagic vacuole, with ninaE17,multivesicular body, with ninaE17,lysosome, with ninaE17,retina,endoplasmic reticulum,Golgi apparatus,rhabdomere,eye,photoreceptor cell & rough endoplasmic reticulum,photoreceptor cell & Golgi apparatus,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,endocytic vesicle,photoreceptor cell,eye photoreceptor cell,conditional,rhabdomere & actin filament,endoplasmic reticulum, with ninaEP37H,mitochondrion, with ninaEP37H,autophagic vacuole, with ninaEP37H,multivesicular body, with ninaEP37H,lysosome, with ninaEP37H,rhabdomere R1 & microvillus,rhabdomere R2 & microvillus,rhabdomere R3 & microvillus,rhabdomere R4 & microvillus,rhabdomere R5 & microvillus,rhabdomere R6 & microvillus,eye disc" FBgn0002121 l(2)gl lethal (2) giant larvae http://flybase.net/reports/FBgn0002121.html protein_coding_gene "0017022=myosin binding, 0004860=protein kinase inhibitor activity, 0045159=myosin II binding, 0000149=SNARE binding" "0030036=actin cytoskeleton organization, 0045196=establishment or maintenance of neuroblast polarity, 0008283=cell proliferation, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0045746=negative regulation of Notch signaling pathway, 0007269=neurotransmitter secretion, 0007406=negative regulation of neuroblast proliferation, 0045184=establishment of protein localization, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0002009=morphogenesis of an epithelium, 0019991=septate junction assembly, 0016334=establishment or maintenance of polarity of follicular epithelium, 0007423=sensory organ development, 0016333=morphogenesis of follicular epithelium, 0008360=regulation of cell shape, 0008105=asymmetric protein localization, 0035293=chitin-based larval cuticle pattern formation, 0042127=regulation of cell proliferation, 0007179=transforming growth factor beta receptor signaling pathway, 0007314=oocyte anterior/posterior axis specification, 0051726=regulation of cell cycle, 0035212=cell competition in a multicellular organism, 0051668=localization within membrane, 0008104=protein localization, 0007391=dorsal closure, 0072697=protein localization to cell cortex, 0007559=histolysis, 0090163=establishment of epithelial cell planar polarity, 0007399=nervous system development, 0098725=symmetric cell division, 0016082=synaptic vesicle priming, 0006469=negative regulation of protein kinase activity, 0016335=morphogenesis of larval imaginal disc epithelium, 0045175=basal protein localization, 0030154=cell differentiation, 0000132=establishment of mitotic spindle orientation, 0045200=establishment of neuroblast polarity, 0001738=morphogenesis of a polarized epithelium, 0045176=apical protein localization, 0048730=epidermis morphogenesis, 0016325=oocyte microtubule cytoskeleton organization, 0045167=asymmetric protein localization involved in cell fate determination, 0008285=negative regulation of cell proliferation, 0035070=salivary gland histolysis, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0016336=establishment or maintenance of polarity of larval imaginal disc epithelium, 0055059=asymmetric neuroblast division, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development" "0005886=plasma membrane, 0005938=cell cortex, 0005578=proteinaceous extracellular matrix, 0008021=synaptic vesicle, 0016327=apicolateral plasma membrane, 0016323=basolateral plasma membrane, 0005920=smooth septate junction, 0030863=cortical cytoskeleton, 0005856=cytoskeleton, 0005918=septate junction, 0005614=interstitial matrix, 0005829=cytosol, 0005737=cytoplasm" "lethal- giant-larvae, LGL, Lethal giant larvae, D-LGL, L(2)gl, l(2) giant larvae, MENE (2L)-B, dlgl, Lgl, Complementation group 2.1, gl, p127l(2)gl, Lethal (2) giant larvae, lethal giant larvae, Lethal Giant Larvae, l(2), lethal giant larva, l(2)giant larvae, l(2) giant larva, lgl, lethal-giant-larvae, Lethal(2)giant larvae, lethal giant larve, lethal-2-giant larvae, p127[l(2)gl], lethal(2) giant larvae, Lethal (2) giant larva, l[[2]]gl, Lethal-giant-larvae, lethal(2)-giant larvae, Lethal-2-giant larvae, CG2671, l-gl, p127, lethal(2)giant larvae, L(2)GL" "IPR013905=Lethal giant larvae (Lgl)-like, C-terminal domain, IPR013577=Lethal giant larvae homologue 2, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR000664=Lethal(2) giant larvae protein" CG2671 16-Dec-15 2015_12 "ENSDARG00000009693(llgl1),ENSDARG00000023920(llgl2)" "YPR032W(SRO7),YBL106C(SRO77)" "ENSXETG00000005768(LLGL1),ENSXETG00000012529(llgl2)" "ENSMUSG00000020536(Llgl1),ENSMUSG00000020782(Llgl2)" "ENSG00000131899(LLGL1),ENSG00000073350(LLGL2)" " embryonic stage , larval stage , adult stage , adult stage && oogenesis stage " " hypophysis

, ventral nerve cord commissure

, imaginal disc

, embryonic/larval salivary gland

, ventral nerve cord

, embryonic/larval fat body

, embryonic/larval proventriculus

, larval muscle system

, ring gland

, embryonic/larval hindgut

, neuroblast

, supraesophageal ganglion

, embryonic/larval salivary gland duct

, head

, epidermis

, embryonic optic lobe primordium

, pharyngeal muscle

, ovary

, longitudinal connective

, larval brain

, embryonic/larval pharynx

" "viable,neuroanatomy defective,lethal,recessive,hyperplasia,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,male sterile,maternal effect,female sterile,wild-type,lethal - all die before end of P-stage,partially,some die during pharate adult stage,tumorigenic,decreased cell number,somatic clone,neoplasia,somatic clone - Minute background,cell lethal,decreased cell size,melanotic mass phenotype,large body,cell polarity defective,cell growth defective,increased cell death,cell non-autonomous,planar polarity defective,germline clone,lethal - all die before end of pupal stage,some die during pupal stage,size defective,lethal - all die before end of embryonic stage,paternal effect,some die during embryonic stage" "oocyte nucleus,microtubule & oocytemat.ë±Tub67C.THsimVP16,epithelium,female germline cyst,type I neuroblast,supernumerary,type II neuroblast,secondary neuroblast,imaginal disc,embryonic/larval brain,eye disc,somatic clone,egg chamber,oocyte associated follicular epithelium,follicle cell,embryonic/larval salivary gland,larval brain & neuroblast | supernumerary,neuroblast & larval brain & third instar larva,wing disc,ventral thoracic disc,dorsal mesothoracic disc & epithelial cell,ventral thoracic disc & epithelial cell,border follicle cell,mechanosensory chaeta,heat sensitive,external sensory organ,male genitalia,socket,tormogen cell,eo neuron,extended germ band embryo,maternal effect,embryonic epidermis,embryonic ventral epidermis,embryonic leading edge cell,cephalopharyngeal skeleton,filzkorper,denticle belt,embryonic head,embryonic/larval midgut,germarium,ovary,pupa,nurse cell,stage S9 oocyte,oocyte,oocyte & cytoskeleton | conditional ts,nurse cell & cytoskeleton | conditional ts,optic lobe,adherens junction,embryonic/larval corpus allatum,prothoracic gland,trichogen cell,thecogen cell,epithelial cell,proximal,somatic clone - Minute background,distal,ectopic,germline clone,neuroblast,EL neuron,cuticle,wing,anterior/posterior compartment boundary,wing vein,egg,embryonic/larval lymph gland,Malpighian tubule,dorsal triple row,chemosensory ventral triple row bristle,dorsal double row,ventral double row,crossvein,embryonic/first instar larval cuticle,microtubule & oocyte | germ-line clone,cell non-autonomous,denticle,adult head,brain,embryonic/larval neuroblast,haltere disc,prothoracic leg disc,metathoracic leg disc,embryonic/larval optic lobe,larval brain | posterior & neuroblast | supernumerary,larval brain | posterior & neuron,external sensory organ precursor cell IIb,external sensory organ precursor cell IIa,endosomeneur-P72,sensory mother cell" FBgn0021760 chb chromosome bows http://flybase.net/reports/FBgn0021760.html "FBgn0041101, FBgn0041587, FBgn0043506, FBgn0045153, FBgn0045266, FBgn0045320, FBgn0047200, FBgn0052435" protein_coding_gene "0005525=GTP binding, 0008017=microtubule binding" "0007282=cystoblast division, 0007051=spindle organization, 0000022=mitotic spindle elongation, 0046580=negative regulation of Ras protein signal transduction, 0051315=attachment of mitotic spindle microtubules to kinetochore, 0019827=stem cell maintenance, 0048477=oogenesis, 0040001=establishment of mitotic spindle localization, 0035099=hemocyte migration, 0007411=axon guidance, 0030723=ovarian fusome organization, 0000070=mitotic sister chromatid segregation, 0007067=mitotic nuclear division, 0046602=regulation of mitotic centrosome separation, 0007052=mitotic spindle organization, 0051225=spindle assembly, 0043148=mitotic spindle stabilization, 0016325=oocyte microtubule cytoskeleton organization" "0005819=spindle, 0005634=nucleus, 0035371=microtubule plus-end, 0005813=centrosome, 0005876=spindle microtubule, 0000776=kinetochore, 0005737=cytoplasm, 0000775=chromosome, centromeric region, 0005875=microtubule associated complex, 0005815=microtubule organizing center, 0030426=growth cone, 0000922=spindle pole, 0045169=fusome, 0045172=germline ring canal, 0005827=polar microtubule" "NEST:bs28g05, MESR7, multiple asters, clasp, mast/orbit, orbit/mast, NEST:bs17d05, DMAP160, Chb, Mast, NEST:bs13a06, unnamed, dCLASP, MAST, BcDNA:LD31673, Orbit/MAST, 0686/07, v40, Orbit/Mast, CG32435, mast, orbit/MAST, chb/mast/orbit, MAST/Orbit, chb(v40), Misexpression suppressor of ras 7, Mast/Orbit, orbit/clasp, anon-WO0104295, CLASP, Orbit, orbit, Orbit/Mast/CLASP, orb" "IPR011989=Armadillo-like helical, IPR021133=HEAT, type 2, IPR024395=CLASP N-terminal domain, IPR016024=Armadillo-type fold" CG32435 16-Dec-15 2015_12 "ENSDARG00000020345(clasp2),ENSDARG00000010280(LOC562077),ENSDARG00000007894" "WBGene00015580(C07H6.3),WBGene00000549(cls-2)" ENSXETG00000000840(CLASP1) "ENSMUSG00000064302(Clasp1),ENSMUSG00000033392(Clasp2)" "ENSG00000074054(CLASP1),ENSG00000163539(CLASP2)" " adult stage | male , embryonic stage -- adult stage " organism

" embryonic stage | stage 4 , adult stage , larval stage " " ovary

, larval brain

" "female sterile,male sterile,viable,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,sterile,aging defective,visible,maternal effect,wild-type,cell adhesion defective,cytokinesis defective" "spindle | maternal effect,centrosome | maternal effect,egg chamber,ovary,oocyte,female germline stem cell,ovariole,cystoblast,cystocyte,spindle,mitotic cell cycle,nurse cell ring canal,nurse cell,microtubule,microtubule organizing center,testis,spermatozoon,mitotic cell cycle[-],anterior fascicle & synapse,intersegmental nerve,embryonic/larval neuron,centriole,larval brain & nuclear chromosome,ganglion & mitotic cell cycle & larva,mitotic cell cycle & neuroblast,egg,maternal effect,nucleus | embryonic stage | maternal effect,mitotic cell cycle | maternal effect,mitotic cell cycle & spindle | maternal effect,mitotic cell cycle & centrosome | maternal effect,mitotic cell cycle & midbody | maternal effect,wing,eye,ommatidium,macrochaeta,mitotic metaphase,presumptive embryonic/larval central nervous system,embryonic hemocyte,nucleus & spermatocyte,Nebenkern & spermatocyte,spindle & spermatocyte,fascicle,pCC neuron,spindle microtubule & kinetochore microtubule,metaphase & condensed nuclear chromosome,anaphase & condensed nuclear chromosome,mitosis & nuclear chromosome,kinetochore,metaphase & condensed nuclear chromosome | maternal effect,chromosome, centromeric region | maternal effect,mitotic prometaphase | maternal effect,centrosome,pericentriolar material" DRSC11469 I 1.621915307 1.423389752 0.498923029 0.010602698 -0.25351616 0.697159101 FBgn0041604 dlp dally-like http://flybase.net/reports/FBgn0041604.html "FBgn0036434, FBgn0036435, FBgn0052146" protein_coding_gene "0017147=Wnt-protein binding, 0043395=heparan sulfate proteoglycan binding" "0008587=imaginal disc-derived wing margin morphogenesis, 0048749=compound eye development, 0045570=regulation of imaginal disc growth, 0050908=detection of light stimulus involved in visual perception, 0008101=decapentaplegic signaling pathway, 0007224=smoothened signaling pathway, 0007367=segment polarity determination, 0030178=negative regulation of Wnt signaling pathway, 0008589=regulation of smoothened signaling pathway, 0007411=axon guidance, 0045880=positive regulation of smoothened signaling pathway, 0030177=positive regulation of Wnt signaling pathway, 0007528=neuromuscular junction development, 0016055=Wnt signaling pathway, 0048190=wing disc dorsal/ventral pattern formation" "0098595=perivitelline space, 0005576=extracellular region, 0009897=external side of plasma membrane, 0005886=plasma membrane, 0005578=proteinaceous extracellular matrix, 0045202=synapse, 0031594=neuromuscular junction" "dly, dally-like protein, Dally-like, Dlp, Dly, Dallylike, D-glypican B, CG32146, D-gpcB, Dally-like protein, CG5031, CG17703, DLP, CT16138" IPR001863=Glypican CG32146 16-Dec-15 2015_12 ENSDARG00000024588(si:dkey-236e20.9) WBGene00001687(gpn-1) "ENSXETG00000005400(GPC4),ENSXETG00000003037(GPC1)" "ENSMUSG00000031119(Gpc4),ENSMUSG00000058571(Gpc6),ENSMUSG00000034220(Gpc1)" "ENSG00000076716(GPC4),ENSG00000183098(GPC6),ENSG00000063660(GPC1)" "segment polarity phenotype,visible,viable,fertile,lethal,recessive,neuroanatomy defective,neurophysiology defective,partially lethal - majority die,non-rescuable maternal effect,lethal - all die before end of P-stage,some die during pharate adult stage" "denticle,ectopic,embryonic/first instar larval cuticle,wing margin bristle,supernumerary,1st posterior cell,wing,denticle belt,eye,mechanosensory chaeta,eye photoreceptor cell & axon,lamina plexus,medulla,ventral,presynaptic active zone | third instar larval stage,eye photoreceptor cell & axonfz-D21),ommatidium,interommatidial bristle,wing disc,sensory mother cell,somatic clone,wing margin,wing sensillum,presynaptic active zone | larval stageunspecified,NMJ bouton | larval stage,posterior,cell non-autonomous,chaeta" DRSC10281 IE -2.669872293 0.362497182 -2.72282976 3.668203824 -0.246759135 -0.034558914 FBgn0001319 kn knot http://flybase.net/reports/FBgn0001319.html "FBgn0014142, FBgn0033967" protein_coding_gene "0003677=DNA binding, 0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0045087=innate immune response, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035289=posterior head segmentation, 0035291=specification of segmental identity, intercalary segment, 0007526=larval somatic muscle development, 0035288=anterior head segmentation, 0035203=regulation of lamellocyte differentiation, 0007389=pattern specification process, 0007367=segment polarity determination, 0035287=head segmentation, 0016204=determination of muscle attachment site, 0042694=muscle cell fate specification, 0007474=imaginal disc-derived wing vein specification, 0048813=dendrite morphogenesis, 0046427=positive regulation of JAK-STAT cascade, 0001700=embryonic development via the syncytial blastoderm, 0006355=regulation of transcription, DNA-templated, 0007350=blastoderm segmentation, 0048814=regulation of dendrite morphogenesis, 0010468=regulation of gene expression, 0009608=response to symbiont, 0007476=imaginal disc-derived wing morphogenesis" 0005634=nucleus "coe, CG10197, knot, DmCOE, col, collier/knot, Collier, Collier-Knot, Kn, KNOT, collier, Knot, Collier/Knot, knotted, Col, Col/Kn" "IPR014756=Immunoglobulin E-set, IPR018350=Transcription factor COE, conserved site, IPR003523=Transcription factor COE, IPR002909=IPT domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR013783=Immunoglobulin-like fold" CG10197 16-Dec-15 2015_12 "ENSDARG00000016300(ebf3),ENSDARG00000042525(coe2),ENSDARG00000016116" WBGene00006743(unc-3) "ENSXETG00000011309(EBF3),ENSXETG00000010153(Q6P4K7_XENTR)" "ENSMUSG00000057098(Ebf1),ENSMUSG00000010476(Ebf3),ENSMUSG00000022053(Ebf2),ENSMUSG00000053552(Ebf4)" "ENSG00000164330(EBF1),ENSG00000108001(EBF3),ENSG00000221818(EBF2),ENSG00000088881(EBF4)" " embryonic stage , larval stage | third instar " " embryonic mandibular segment

, dorsal mesothoracic disc | anterior/posterior compartment boundary | anterior to

, head mesoderm

" larval stage | third instar dorsal mesothoracic disc | anterior/posterior compartment boundary | anterior to

"neuroanatomy defective,smell perception defective,chemical sensitive,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage,immune response defective,visible,wild-type,viable,recessive,somatic clone,lethal,cell non-autonomous" "A1-7 dorsal acute muscle 3,A1-7 dorsal acute muscle 2,ectopic,wing vein L3,wing vein L4,dendritic tree | larval stage2-21,class I dendritic arborizing neuron | larval stage,class II dendritic arborizing neuron | larval stage,class III dendritic arborizing neuron | larval stage,lateral process,abdominal 1 dorsal acute muscle 3,abdominal 2 dorsal acute muscle 3,abdominal 3 dorsal acute muscle 3,abdominal 4 dorsal acute muscle 3,abdominal 5 dorsal acute muscle 3,abdominal 6 dorsal acute muscle 3,abdominal 7 dorsal acute muscle 3,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,hypostomal sclerite,heat sensitive,cephalopharyngeal skeleton,1st posterior cell,wing,submarginal cell,2nd posterior cell,3rd posterior cell,wing | P-stage,wing vein,posterior crossvein,anterior crossvein,wing cell,wing basal cell 1,wing cell & wing vein L3 & wing vein L4,dorsal multidendritic neuron ddaC,somatic clone,class IV dendritic arborizing neuron,dendrite | somatic clone,embryonic head,embryonic/larval somatic muscle,mesothoracic dorsal acute muscle 4,metathoracic dorsal acute muscle 4,prohemocyte,embryonic/larval lymph gland,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 4,A1-7 dorsal oblique muscle 5,sensillum campaniformium of dorsal radius,wing cell & wing vein L3 & wing vein L4 | somatic clone,anterior compartment,cell non-autonomous,wing margin bristle,macrochaeta,hypopharyngeal lobe,ventral arm of pharyngeal sclerite,dendritic tree | somatic clone,distal,wing vein L5,proximal,wing vein L2,class I dendritic arborizing neuron,dendrite221,dendritesmid-C161,class II dendritic arborizing neuron,class III dendritic arborizing neuron,dendritic arborizing neuron,lamellocyte,supernumerary,melanotic mass,crystal cell,posterior signalling centre of lymph gland primary lobe" FBgn0010825 Gug Grunge http://flybase.net/reports/FBgn0010825.html "FBgn0011373, FBgn0011523, FBgn0020427, FBgn0024868, FBgn0035897" protein_coding_gene "0004407=histone deacetylase activity, 0003677=DNA binding, 0003714=transcription corepressor activity, 0070491=repressing transcription factor binding" "0007526=larval somatic muscle development, 0035282=segmentation, 0001654=eye development, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0007480=imaginal disc-derived leg morphogenesis, 0009880=embryonic pattern specification, 0035065=regulation of histone acetylation, 0002121=inter-male aggressive behavior, 0045879=negative regulation of smoothened signaling pathway, 0008586=imaginal disc-derived wing vein morphogenesis, 0007379=segment specification" "0005705=polytene chromosome interband, 0005634=nucleus" "l(3)j5A3, GUG, atro, gug, grunge, Atrophin, l(3)03928, l(3)01323, CG6964, atrophin, l(3)S146907, Atro, unnamed, l(3)rO116" "IPR000949=ELM2 domain, IPR001005=SANT/Myb domain, IPR002951=Atrophin-like, IPR017884=SANT domain, IPR009057=Homeodomain-like" CG6964 16-Dec-15 2015_12 WBGene00001194(egl-27) "ENSMUSG00000039852(Rere),ENSMUSG00000004263(Atn1)" "ENSG00000142599(RERE),ENSG00000111676(ATN1)" "lethal,partially,heat sensitive,neuroanatomy defective,progressive,viable,fertile,increased cell death,locomotor behavior defective,behavior defective,male limited,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,germline clone,rescuable maternal effect,visible,somatic clone,planar polarity defective,homeotic,cell polarity defective,cell non-autonomous" "wing vein,ectopic,somatic clone,wing margin,eye,autophagic vacuoleGMR.PU,eye photoreceptor cell,drug conditional,retina,temperature conditional,progressive,leg,wing,embryonic/larval brain,embryonic abdomen,germline clone,maternal effect,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic segment,embryonic head,non-rescuable maternal effect,embryonic/first instar larval cuticle,rescuable maternal effect,ventral,leg sensillum,cell non-autonomous,leg sensillum & prothoracic femur | somatic clone,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,prothoracic tarsal bristle,mesothoracic tarsal bristle,metathoracic tarsal bristle,prothoracic tibial transverse row bristle,sex comb,coxa,trochanter,femur,proximal,bract,arista,unguis,ocellar triangle,triple row,trichome of the posterior wing margin,cone cell,supernumerary,cell autonomous,ommatidium,adult thorax,egg,embryo,adult abdominal segment 6,adult abdominal segment 5,wing hair,mesothoracic tergum,rhabdomere,denticle belt,embryonic epidermis,embryonic/larval neuron,tarsal segment,interommatidial bristle,mitochondrionGMR.PU,arista lateral" FBgn0038818 Nep4 Neprilysin 4 http://flybase.net/reports/FBgn0038818.html protein_coding_gene "0004175=endopeptidase activity, 0004222=metalloendopeptidase activity" 0006508=proteolysis "0016021=integral component of membrane, 0016529=sarcoplasmic reticulum" "CG4058, DmeNEP4, NEP4, dNEP4, nep4, neprilysin 4, neprilysin4" "IPR018497=Peptidase M13, C-terminal domain, IPR024079=Metallopeptidase, catalytic domain, IPR000718=Peptidase M13, IPR008753=Peptidase M13, N-terminal domain" CG4058 16-Dec-15 2015_12 ENSDARG00000026398(LOC560703) WBGene00020230(nep-2) "locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable" "I band | third instar larval stageMef2.5xCD,sarcomere | third instar larval stageMef2.5xCD,Z disc | third instar larval stageMef2.5xCD,embryonic/larval somatic muscle | third instar larval stage,sarcoplasmic reticulum | third instar larval stageMef2.5xCD,embryonic/larval somatic muscle | larval stage" FBgn0003502 Btk29A Btk family kinase at 29A http://flybase.net/reports/FBgn0003502.html FBgn0032011 protein_coding_gene "0005524=ATP binding, 0004713=protein tyrosine kinase activity" "0007391=dorsal closure, 0008258=head involution, 0030723=ovarian fusome organization, 0007301=female germline ring canal formation, 0007485=imaginal disc-derived male genitalia development, 0007619=courtship behavior, 0048477=oogenesis, 0007300=ovarian nurse cell to oocyte transport, 0030717=karyosome formation, 0007349=cellularization, 0030036=actin cytoskeleton organization, 0042023=DNA endoreduplication, 0007424=open tracheal system development, 0007254=JNK cascade, 0007476=imaginal disc-derived wing morphogenesis, 0046960=sensitization, 0030833=regulation of actin filament polymerization, 0018108=peptidyl-tyrosine phosphorylation, 0007435=salivary gland morphogenesis, 0035556=intracellular signal transduction, 0035277=spiracle morphogenesis, open tracheal system, 0044719=regulation of imaginal disc-derived wing size, 0008340=determination of adult lifespan, 0006468=protein phosphorylation" "0005737=cytoplasm, 0045177=apical part of cell, 0071944=cell periphery, 0045172=germline ring canal, 0005886=plasma membrane" "S13, Src oncogene 29A, fickle, Tec, Src2, Btk29A type 2, Tec29, SRC 29A, EC2-9, src-4, btk29a, CG8049, Btk29a, Dsrc28C, DSrc28, C-src2, Btk, fic, tec29, c-src/fps, Dsrc29A, src2, src28C, DTec29, btk, src4, CG18355, C-src4, btk29, dsrc29A, Src29A, Tec29A, Dm SRC2, btk29A, CT41718, CT2415" "IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR001452=SH3 domain, IPR001849=Pleckstrin homology domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR001562=Zinc finger, Btk motif, IPR000980=SH2 domain, IPR017441=Protein kinase, ATP binding site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG8049 16-Dec-15 2015_12 "ENSDARG00000004433(btk),ENSDARG00000017565(itk),ENSDARG00000030538" ENSXETG00000009831(TEC) "ENSMUSG00000029217(Tec),ENSMUSG00000020395(Itk),ENSMUSG00000031264(Btk)" "ENSG00000135605(TEC),ENSG00000113263(ITK),ENSG00000010671(BTK),ENSG00000074966(TXK)" " prepupal stage--pupal stage , adult stage , larval stage | third instar , embryonic stage | stage 8-11 , embryonic stage | stage 12 , embryonic stage | stage 9-12 , adult stage && oogenesis stage , pupal stage , embryonic stage | stage 16-17 , embryonic stage | stage 12-14 , embryonic stage | stage 15 , embryonic stage | stage 5-6 , larval stage--pupal stage , embryonic stage | stage 5 , embryonic stage , oogenesis stage && adult stage | female , larval stage--adult stage , prepupal stage , embryonic stage | stage 1-4 , adult stage | female , embryonic stage | stage >=12 " " pupal/adult digestive system | restricted

, adult dorsal vessel

, imaginal disc

, procephalic segment

, gonad

, stomodeal invagination | anterior

, adult head

, proctodeum

, nurse cell

, imaginal disc | restricted

, epidermis

, embryonic/larval salivary gland

, trachea | restricted

, midline glial cell

, proctodeum | anlage

, gnathal segment

, embryonic/larval posterior spiracle

, mushroom body

, male genital disc | restricted

, amnioserosa | anlage

, neuron | subset

, amnioserosa

, genital disc | restricted

, ovary

, adult proventriculus

, posterior midgut proper primordium

, central nervous system

, histoblast

, ejaculatory bulb | restricted

, oocyte

,

ubiquitous , anterior midgut proper primordium

, lymph gland

, antennal lobe

, embryonic central nervous system | presumptive

, ectoderm

segmentally repeated , lamellocyte

, labral segment

" " embryonic stage | stage >=13 , embryonic stage | extended germ band , larval stage | first instar , adult stage && oogenesis stage , embryonic stage | 4-14 hr , embryonic stage | stage >=5 , embryonic stage | >=4-6 hr " " peripheral nervous system

, embryonic central nervous system

, organism | striped

, larval central nervous system

, ring canal

, organism

" "lethal,recessive,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially,short lived,mating defective,male,male sterile,behavior defective,wild-type,size defective" "spectrosomeC587,germarium,cephalopharyngeal skeleton,mouth hooks,posterior,epipharyngeal sclerite,dorsal bridge,vertical bridge,anterior,labrum,hypostomal sclerite,embryonic head,presumptive embryonic salivary gland,egg chamber,nurse cell ring canal,egg,taenidial fold,embryonic/larval trachea,embryonic/first instar larval cuticle,basal apodeme of penis,ectopic,male genitalia,posterior ejaculatory duct,female germline cell,embryonic/larval salivary gland,actin filament | embryonic stage 5 | germline clone | maternal effect,embryonic/larval posterior spiracle,germline clone,egg chamber & actin cytoskeleton | germ-line clone,karyosome,nurse cell fusome,actin filament | germline clone,salivary gland common duct primordium,actin cytoskeleton,embryonic/larval muscle system,stage S14 oocyte,wing" DRSC02008 E 0.949210601 0.550633296 1.934739552 1.40421842 0.887848136 0.650728655 FBgn0003256 rl rolled http://flybase.net/reports/FBgn0003256.html "FBgn0005693, FBgn0039983, FBgn0042217, FBgn0047177, FBan0012559" protein_coding_gene "0008134=transcription factor binding, 0004705=JUN kinase activity, 0005524=ATP binding, 0004707=MAP kinase activity, 0004674=protein serine/threonine kinase activity, 0019901=protein kinase binding" "0016242=negative regulation of macroautophagy, 0007507=heart development, 0007067=mitotic nuclear division, 0046534=positive regulation of photoreceptor cell differentiation, 0006355=regulation of transcription, DNA-templated, 0007476=imaginal disc-derived wing morphogenesis, 0007173=epidermal growth factor receptor signaling pathway, 0071276=cellular response to cadmium ion, 0007169=transmembrane receptor protein tyrosine kinase signaling pathway, 0006974=cellular response to DNA damage stimulus, 2001023=regulation of response to drug, 0043066=negative regulation of apoptotic process, 0007474=imaginal disc-derived wing vein specification, 0008586=imaginal disc-derived wing vein morphogenesis, 0009267=cellular response to starvation, 0045467=R7 cell development, 0008293=torso signaling pathway, 0008595=anterior/posterior axis specification, embryo, 0006468=protein phosphorylation, 0007552=metamorphosis, 0007369=gastrulation, 0045500=sevenless signaling pathway, 0000165=MAPK cascade, 0048149=behavioral response to ethanol, 0046579=positive regulation of Ras protein signal transduction, 0034334=adherens junction maintenance, 0050804=regulation of synaptic transmission, 0050803=regulation of synapse structure or activity, 0008284=positive regulation of cell proliferation, 0034614=cellular response to reactive oxygen species, 0090303=positive regulation of wound healing, 0071243=cellular response to arsenic-containing substance, 0070374=positive regulation of ERK1 and ERK2 cascade, 2000826=regulation of heart morphogenesis" "0005737=cytoplasm, 0031594=neuromuscular junction, 0005634=nucleus, 0030054=cell junction" "dm-dpERK, Enhancer of seven in absentia 7, Extracellular-signal-related kinase A, MapK, pMAPK, pMapK, CT39192, Rl, phospho-ERK, Sevenmaker, dpMAPK, MAP kinase, erk, rll, 12559, DERK-A, EC2-1, ERK/rolled, Drosophila ERK, Erk, DpErk, DmERK-A, E(sina)7, dpErk, GroupII, SR2-1, Mapk, MAPK, BcDNA:RE08694, Sem, D-ERK, rl/MAPK, ERKA, EY2-2, l(2R)EMS45-39, Erk/Map kinase, Rolled, MAP-k, EK2-1, rl/ERK, dpERK, RL, pERK, ERK, Su(Raf)2B, DmErk, SEM, Extracellular-regulated kinase A, mitogen-activated protein kinase, DpERK, l(2)41Ac, CG12559, roll, Diphospho-ERK, ErkA, MAP-kinase, DERK, dp-ERK, sem, DmERKA, CT34260, mapk, mitogen activated protein kinase, extracellular signal-regulated kinase, sevenmaker, Erk MAP kinase, Dsor2, dpERK1, dpERk, ERK-A, Erk1, extracellular signal-regulated kinase A, DmMAPK, CG18732, dERK, ERKa" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR003527=Mitogen-activated protein (MAP) kinase, conserved site, IPR008349=Mitogen-activated protein (MAP) kinase, ERK1/2, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG12559 16-Dec-15 2015_12 "ENSDARG00000027552(mapk1),ENSDARG00000070573(LOC100330818)" "YBL016W(FUS3),YGR040W(KSS1)" WBGene00003401(mpk-1) ENSXETG00000018576(mapk1) ENSMUSG00000063358(Mapk1) "ENSG00000100030(MAPK1),ENSG00000102882(MAPK3)" embryonic stage " embryonic/larval tracheal system

, mesoderm

" "lethal,recessive,viable,visible,developmental rate defective,large body,mitotic cell cycle defective,female sterile,dominant,partially,lethal - all die before end of larval stage,some die during larval stage,visual behavior defective,maternal effect,neuroanatomy defective,neurophysiology defective,chemical sensitive,radiation sensitive,lethal - all die before end of pupal stage,some die during pupal stage,wound healing defective,increased cell number,chemical resistant,short lived,partially lethal - majority die,decreased cell size,size defective" "wing vein L5,wing vein L4,rhabdomere,ommatidium,cone cell,eye,wing blade,glial cell,trichogen cell,mesothoracic tergum,wing,wing vein,photoreceptor cell R7,supernumerary,ectopic,macrochaeta,midline glial cell,eye photoreceptor cell,embryonic abdominal segment,photoreceptor cell,imaginal disc,pigment cell,denticle belt,maternal effect,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,bouton,NMJ bouton,bract,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,wing vein L3,tracheal branch primordium,male germline cell,cyst progenitor cell,germline stem cell,adult heart muscle" DRSC07833 EK 1.253037093 -0.528349543 4.703266859 -1.315218946 -7.108172478 -4.861420244 FBgn0003861 trp transient receptor potential http://flybase.net/reports/FBgn0003861.html protein_coding_gene "0042803=protein homodimerization activity, 0010461=light-activated ion channel activity, 0005515=protein binding, 0005262=calcium channel activity, 0015279=store-operated calcium channel activity, 0046982=protein heterodimerization activity, 0005218=intracellular ligand-gated calcium channel activity, 0005516=calmodulin binding, 0042802=identical protein binding" "0030845=phospholipase C-inhibiting G-protein coupled receptor signaling pathway, 0019722=calcium-mediated signaling, 0009416=response to light stimulus, 0008377=light-induced release of internally sequestered calcium ion, 0007603=phototransduction, visible light, 0070588=calcium ion transmembrane transport, 0006816=calcium ion transport, 0008355=olfactory learning, 0007605=sensory perception of sound, 0050908=detection of light stimulus involved in visual perception, 0071454=cellular response to anoxia, 0050962=detection of light stimulus involved in sensory perception, 0008104=protein localization" "0035997=rhabdomere microvillus membrane, 0005886=plasma membrane, 0034703=cation channel complex, 0016028=rhabdomere, 0016027=inaD signaling complex" "gene B, dTrp, DmTRP, Trp, transient photreceptor potential, CG7875, dTRP, Transient receptor potential protein, INAD localization-B, 559, Cosens-Manning mutant, Transient Receptor Potential, idl-B, TRP" "IPR005821=Ion transport domain, IPR004729=Transient receptor potential channel, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR002153=Transient receptor potential channel, canonical, IPR013555=Transient receptor ion channel domain" CG7875 16-Dec-15 2015_12 "ENSDARG00000062183(LOC566436),ENSDARG00000070504,ENSDARG00000070507(LOC555897),ENSDARG00000060837" WBGene00006615(trp-2) "ENSXETG00000001811(TRPC4),ENSXETG00000012403(TRPC5)" " adult stage , pupal stage | late " " ocellus

, adult head

, eye

, adult head

{ - ey } , photoreceptor cell

" " pupal stage | 75 hr , adult stage , pupal stage | >=70 hr " " adult antennal nerve

, rhabdomere

, eye

, photoreceptor cell

, antennal segment 3

, cornea

, adult head

" "neurophysiology defective,neuroanatomy defective,visual behavior defective,viable,wild-type,smell perception defective,heat sensitive,recessive,dominant,auditory perception defective,semidominant" "rhabdomere, with trp3.cHa,rhabdomere, with trp1234.cHa,photoreceptor cell,rhabdomere,eye photoreceptor cell,retina,conditional,rhabdomere | conditional,rhabdomere, with trp9,antenna,heat sensitive,photoreceptor,photoreceptor cell & axon,ommatidium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0263391 hts hu li tai shao http://flybase.net/reports/FBgn0263391.html "FBgn0004873, FBgn0010467, FBgn0010476, FBgn0021853, FBgn0022142, FBgn0027664, FBgn0085226" protein_coding_gene 0003779=actin binding "0072499=photoreceptor cell axon guidance, 0008302=female germline ring canal formation, actin assembly, 0030723=ovarian fusome organization, 0007411=axon guidance, 0048134=germ-line cyst formation, 0070050=neuron cellular homeostasis, 0007294=germarium-derived oocyte fate determination, 0048477=oogenesis, 0045214=sarcomere organization, 0031987=locomotion involved in locomotory behavior, 0061572=actin filament bundle organization, 0051297=centrosome organization, 0048135=female germ-line cyst formation, 0007527=adult somatic muscle development, 0030724=testicular fusome organization, 0007282=cystoblast division, 0030721=spectrosome organization, 0000212=meiotic spindle organization, 0045478=fusome organization" "0016328=lateral plasma membrane, 0005737=cytoplasm, 0005811=lipid particle, 0035183=female germline ring canal inner rim, 0005886=plasma membrane, 0045172=germline ring canal, 0005884=actin filament, 0045170=spectrosome, 0045169=fusome" "Hts-RC, Ovhts, adducin, Hu-li tai shao, Hu-li-tai-shao, hu-li tai-shao, HtsRC, EST D, l(2)00634, CG43443, CG9325, add, HtsF, Hu-li Tai shao, HTS, Hu li tai shao, CG34197, ADD-87, Adducin-like 56D, adducin-like, 1B1, Hu Li Tai Shao, Adducin-like-56D, HTS-R1, ovarian hu-li tai shao-ring canal protein, Ovhts-RC, Hu li-tai shao, htsRC, Adducin, Adducin-like, Hts, add-like, hu-li tai shao, l(2)01103, hu-li tai shao protein, HTS_DROME, Hu-li tai-shao, l(2)k06121, l(2)k14523, HTS-RC, Add, anon-EST:Posey9, Add-hts" "IPR001303=Class II aldolase/adducin N-terminal, IPR027774=Protein hu-li tai shao" CG43443 16-Dec-15 2015_12 "ENSDARG00000022682(add1),ENSDARG00000040874(add3a),ENSDARG00000056250(add3b),ENSDARG00000062698(add2)" WBGene00000072(add-1) "ENSXETG00000008015(add1),ENSXETG00000008519(ADD2)" "ENSMUSG00000029106(Add1),ENSMUSG00000025026(Add3),ENSMUSG00000030000(Add2)" "ENSG00000087274(ADD1),ENSG00000148700(ADD3),ENSG00000075340(ADD2)" " adult stage | male , adult stage && oogenesis stage | stage S7 , adult stage && oogenesis stage | stage S1-14 , pupal stage , embryonic stage | early , adult stage | female , larval stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S7-10 , adult stage && oogenesis stage | stage S10-14 , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >=S10 , embryonic stage | stage 9 , embryonic stage | stage >9 , adult stage && oogenesis stage | stage S9,10 , embryonic stage | stage 2,3 , oogenesis stage | stage S7-10 , embryonic stage | stage 1,2 " " nurse cell

, oocyte

,

anterior{ 0 spir* } , ovary

{ $ swa* } ,

anterior | dorsal{ 0 capu* } , germarium region 1,2

,

anterior | gradient , oocyte | anterior

, ovary

, neuroblast

, embryonic central nervous system

,

anterior , ovary

{ 0 stau* } ,

anterior-posterior-gradient{ 0 exu* } ,

anterior | dorsal{ 0 exu* } ,

anterior | dorsal , nurse follicle cell

,

anterior | dorsal{ 0 stau* } ,oocyte | anterior " " embryonic stage , adult stage && oogenesis stage | early , adult stage && oogenesis stage | stage S1-10 , adult stage && oogenesis stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage S1-13 , adult stage && oogenesis stage | stage S11-12 , embryonic stage | stage 4-15 , adult stage && oogenesis stage | stage S1-8 , adult stage && oogenesis stage | stage S1-14 " " embryonic/larval muscle system

, embryonic central nervous system

, spectrosome &&of germarium

, oocyte

, embryonic epidermis

, fusome

, germarium region 2a && nurse cell ring canal

, nurse cell ring canal

, oocyte | anterior

,

ubiquitous , embryonic/larval digestive system

, germarium region 3 && nurse cell ring canal

, follicle cell

, germarium region 2b && nurse cell ring canal

, nurse cell

, fusome &&of germarium

" FBgn0001250 if inflated http://flybase.net/reports/FBgn0001250.html protein_coding_gene "0050839=cell adhesion molecule binding, 0050840=extracellular matrix binding, 0046982=protein heterodimerization activity, 0004872=receptor activity, 1990430=extracellular matrix protein binding" "0007608=sensory perception of smell, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0035099=hemocyte migration, 0030239=myofibril assembly, 0051492=regulation of stress fiber assembly, 0045214=sarcomere organization, 0007414=axonal defasciculation, 0035160=maintenance of epithelial integrity, open tracheal system, 0007160=cell-matrix adhesion, 0007435=salivary gland morphogenesis, 0008360=regulation of cell shape, 0016337=single organismal cell-cell adhesion, 0007431=salivary gland development, 0007494=midgut development, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0034446=substrate adhesion-dependent cell spreading, 0007476=imaginal disc-derived wing morphogenesis, 0007427=epithelial cell migration, open tracheal system, 0007411=axon guidance, 0033627=cell adhesion mediated by integrin, 0007298=border follicle cell migration, 0045185=maintenance of protein location, 0007155=cell adhesion, 0016477=cell migration, 0007426=tracheal outgrowth, open tracheal system, 0021551=central nervous system morphogenesis, 0016203=muscle attachment" "0042383=sarcolemma, 0009925=basal plasma membrane, 0005886=plasma membrane, 0005925=focal adhesion, 0005887=integral component of plasma membrane, 0008305=integrin complex" "alphaPS2 integrin, in, alpha2Int, alphaPS2m8, PS2(m8), alpha[[PS2(ms8)]], ItgaPS2, PS2(m8)alpha, alphaPS2 Integrin, alpha-PS2-integrin, alpha[[PS2]] integrin, alphaPS2-integrin, alphaPS2, inf, CT27194, CG9623, PS2(c), aPS2, PSalpha2, alphaPS2C, If, Integrin alphaPS2 subunit, PS2, integrin alphaPS2 subunit, alpha integrin, alpha-integrin, PS2alpha, position-specific antigen 2, alpha2 integrin, alpha[[PS2]], PS 2" "IPR013517=FG-GAP repeat, IPR018184=Integrin alpha chain, C-terminal cytoplasmic region, conserved site, IPR013649=Integrin alpha-2, IPR013519=Integrin alpha beta-propellor, IPR000413=Integrin alpha chain" CG9623 16-Dec-15 2015_12 "ENSDARG00000006353(itga5),ENSDARG00000040342,ENSDARG00000006314(itgav),ENSDARG00000018687(itga2b)" WBGene00003929(pat-2) "ENSXETG00000020282(ITGA8),ENSXETG00000013317(ITGAV)" "ENSMUSG00000026768(Itga8),ENSMUSG00000027087(Itgav),ENSMUSG00000000555(Itga5),ENSMUSG00000034664(Itga2b)" "ENSG00000077943(ITGA8),ENSG00000161638(ITGA5),ENSG00000138448(ITGAV),ENSG00000005961(ITGA2B)" " larval stage | third instar , embryonic stage | stage 4-13 " " peripodial epithelium

, mesoderm

, dorsal mesothoracic disc

" " embryonic stage , larval stage | third instar , embryonic stage | stage >=10 " " gonadal sheath muscle

, pharyngeal muscle

, gonad | restricted

, muscle attachment site

, dorsal mesothoracic disc

, mesoderm

, visceral mesoderm

" "visible,dominant,viable,fertile,lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,poor,cold sensitive,heat sensitive,lethal - all die before end of first instar larval stage,partially lethal - majority die" "gastric caecum,ventral nerve cord,anterior midgut primordium,embryonic/larval somatic muscle,gastric caecum primordium,wing vein,crossvein,presumptive embryonic salivary gland,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/first instar larval cuticle,dorsal,RP3 motor neuron,filopodium & abdominal ventral longitudinal muscle 3,intersegmental nerve,segmental nerve,salivary gland common duct primordium,embryonic/larval salivary gland,wing,embryonic/larval midgut,somatic muscle,embryonic/larval visceral muscle,muscle attachment site,germ layer,visceral mesoderm,extended germ band embryo,midgut constriction,somatic clone,embryonic/larval visceral branch,abdominal 2 segment border muscle,abdominal 3 segment border muscle,abdominal 4 segment border muscle,abdominal 5 segment border muscle,abdominal 6 segment border muscle,abdominal 7 segment border muscle,abdominal 2 lateral longitudinal muscle 1,abdominal 3 lateral longitudinal muscle 1,abdominal 4 lateral longitudinal muscle 1,abdominal 5 lateral longitudinal muscle 1,abdominal 6 lateral longitudinal muscle 1,abdominal 7 lateral longitudinal muscle 1,abdominal 2 ventral longitudinal muscle 1,abdominal 3 ventral longitudinal muscle 1,abdominal 4 ventral longitudinal muscle 1,abdominal 5 ventral longitudinal muscle 1,abdominal 6 ventral longitudinal muscle 1,abdominal 7 ventral longitudinal muscle 1,presumptive embryonic/larval digestive system,muscle attachment site & connecting hemi-adherens junction,muscle attachment site & muscle tendon junction,muscle attachment site & basal lamina,embryonic/larval proventriculus,proventriculus inner layer,cold sensitive,anterior crossvein,wing blade,sarcomere & somatic muscle,actin cytoskeleton | embryonic stage 17,presumptive embryonic/larval muscle system,stage S14 oocyte,hemocyte,eye,heat sensitive,muscle fiber,border follicle cell" DRSC20341 IE -2.655177078 -1.138316328 -3.709081896 -1.432004186 0.041489306 0.447050276 FBgn0260440 spdo sanpodo http://flybase.net/reports/FBgn0260440.html "FBgn0011716, FBgn0010731, FBgn0039785, FBgn0039786, FBgn0051020, FBgn0064900" protein_coding_gene "0005515=protein binding, 0005112=Notch binding" "0008356=asymmetric cell division, 0007422=peripheral nervous system development, 0003007=heart morphogenesis, 0007219=Notch signaling pathway, 0045746=negative regulation of Notch signaling pathway, 0045035=sensory organ precursor cell division, 0007423=sensory organ development" "0030863=cortical cytoskeleton, 0005737=cytoplasm, 0031410=cytoplasmic vesicle, 0005886=plasma membrane, 0016021=integral component of membrane, 0005769=early endosome, 0005770=late endosome" "0970/02, CG31020, Spdo, Sanpodo, BcDNA:RE23355" CG31020 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,neuroanatomy defective,visible,somatic clone,size defective,viable" "peripheral nervous system precursor cluster,peripheral nervous system precursor cluster & neuron | supernumerary,embryonic peripheral nervous system & glial cell,presumptive embryonic/larval central nervous system,neuron,cardioblast,thecogen cell & peripheral nervous system,presumptive embryonic/larval peripheral nervous system,CNS glial cell,longitudinal connective,anterior commissure,posterior commissure,abdominal dorsal bipolar neuron dbp,ectopic,dorsal multidendritic neuron,macrochaeta,somatic clone,eo neuron,chaeta,macrochaeta & mesothoracic tergum | somatic clone,GW neuron,EW1 neuron,peripheral nervous system,external sensory organ precursor cell IIb,thecogen cell,multidendritic neuron,precursor,abdominal 1 dorsal bipolar neuron dbp,abdominal 2 dorsal bipolar neuron dbp,abdominal 3 dorsal bipolar neuron dbp,abdominal 4 dorsal bipolar neuron dbp,abdominal 5 dorsal bipolar neuron dbp,abdominal 6 dorsal bipolar neuron dbp,abdominal 7 dorsal bipolar neuron dbp,abdominal 1 basiconical sensillum dbd & embryonic glial cell,abdominal 2 basiconical sensillum dbd & embryonic glial cell,abdominal 3 basiconical sensillum dbd & embryonic glial cell,abdominal 4 basiconical sensillum dbd & embryonic glial cell,abdominal 5 basiconical sensillum dbd & embryonic glial cell,abdominal 6 basiconical sensillum dbd & embryonic glial cell,abdominal 7 basiconical sensillum dbd & embryonic glial cell,external sensory organ,RP2 motor neuron,RP2sib neuron,aCC neuron,pCC neuron,dMP2 neuron,vMP2 neuron,U neuron,Usib neuron,apterous-expressing neuron of the lateral cluster of the thorax,embryonic pericardial cell,embryonic heart cardioblast,embryonic/larval neuroblast,secondary neuroblast,supernumerary,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,abdominal 1 dorsal acute muscle 3,abdominal 2 dorsal acute muscle 3,abdominal 3 dorsal acute muscle 3,abdominal 4 dorsal acute muscle 3,abdominal 5 dorsal acute muscle 3,abdominal 6 dorsal acute muscle 3,abdominal 7 dorsal acute muscle 3,embryonic/larval pericardial cell,scutellar bristle,external sensory organ precursor cell,ectopic | third instar larval stage,wing,wing vein,wing margin,interommatidial bristle,frontal bristle,external sensory organ precursor cell IIIb,trichogen cell,tormogen cell,mesothoracic tergum" FBgn0002783 mor moira http://flybase.net/reports/FBgn0002783.html "FBgn0025464, FBgn0042208" protein_coding_gene "0005515=protein binding, 0003677=DNA binding, 0003713=transcription coactivator activity" "0007474=imaginal disc-derived wing vein specification, 0008586=imaginal disc-derived wing vein morphogenesis, 0022008=neurogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 2000134=negative regulation of G1/S transition of mitotic cell cycle, 0008587=imaginal disc-derived wing margin morphogenesis, 0045088=regulation of innate immune response, 0006338=chromatin remodeling, 0048477=oogenesis, 0045893=positive regulation of transcription, DNA-templated, 0007406=negative regulation of neuroblast proliferation, 0043044=ATP-dependent chromatin remodeling" "0035060=brahma complex, 0005634=nucleus, 0070604=PBAF complex" "Moira, Mor, brahma associated protein 155 kDa, brahma-associated protein 155, CG4275, brahma-like, E(E2F)3B, dmMOIRA, Moi, Swi3D, CG18740, MOR, Bap155/Moira, MOR/BAP155, MOIRA, BAP155, moira, l(3)89B1" "IPR017884=SANT domain, IPR001357=BRCT domain, IPR007526=SWIRM domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like" CG18740 16-Dec-15 2015_12 ENSDARG00000017397(smarcc1) WBGene00004203(psa-1) "ENSXETG00000014492(SMARCC1),ENSXETG00000009486(SMARCC2)" "ENSMUSG00000025369(Smarcc2),ENSMUSG00000032481(Smarcc1)" "ENSG00000139613(SMARCC2),ENSG00000173473(SMARCC1)" " embryonic stage | stage >=9 , adult stage | female , embryonic stage | early , adult stage | male , embryonic stage--pupal stage ," " ventral nerve cord

,

ubiquitous , embryonic brain

, embryonic/larval hindgut

, unfertilized egg

, embryonic/larval midgut

" " embryonic stage | early , embryonic stage | stage >=9 " "

ubiquitous , embryonic/larval hindgut

, ventral nerve cord

, embryonic brain

, embryonic/larval midgut

" "wild-type,visible,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,dominant,enhancer of variegation,non-suppressor of variegation,non-enhancer of variegation,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive" "adult head,dorsal,somatic clone,ocellus,arista,eye,embryonic head,midgut constriction 1,midgut constriction 2,presumptive embryonic/larval peripheral nervous system,ventral nerve cord commissure,wing vein,ectopic,cell | somatic clone,haltere,macrochaeta & haltere | posterior | somatic clone,wing,posterior,wing margin & macrochaeta | somatic clone,prothoracic leg,mesothoracic leg,metathoracic leg,femur,tibia,tarsal segment,mesothoracic tarsal segment,anterior,sex comb,egg,germline clone,dorsal appendage,chorion | germline clone,proximal,metathoracic laterotergite,scutum,genitalia,macrochaeta,lateral process,pharyngeal bars,heat sensitive,wing margin,wing hair,wing sensillum,embryonic/larval neuroblast,ganglion mother cell,type II neuroblast,supernumerary" FBgn0051618 His2A:CG31618 His2A:CG31618 http://flybase.net/reports/FBgn0051618.html FBgn0045839 protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0051298=centrosome duplication, 0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005811=lipid particle, 0005634=nucleus, 0000786=nucleosome" "CG31618, BEST:CK01438" "IPR002119=Histone H2A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG31618 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" DRSC21264 IE -3.116072292 -3.615531647 -6.915272547 -6.035485748 -0.331966247 -1.083879001 FBgn0053900 His2B:CG33900 His2B:CG33900 http://flybase.net/reports/FBgn0053900.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33900 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000558=Histone H2B" CG33900 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053841 His2A:CG33841 His2A:CG33841 http://flybase.net/reports/FBgn0053841.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33841 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A" CG33841 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0041781 SCAR SCAR http://flybase.net/reports/FBgn0041781.html "FBgn0021868, FBgn0022228, FBgn0032324, FBgn0046233" protein_coding_gene "0005515=protein binding, 0003779=actin binding" "0001764=neuron migration, 0007520=myoblast fusion, 0051491=positive regulation of filopodium assembly, 0030036=actin cytoskeleton organization, 0030866=cortical actin cytoskeleton organization, 0051489=regulation of filopodium assembly, 0006909=phagocytosis, 0030029=actin filament-based process, 0001745=compound eye morphogenesis, 0060305=regulation of cell diameter, 0048846=axon extension involved in axon guidance, 0010592=positive regulation of lamellipodium assembly, 0007010=cytoskeleton organization, 0007030=Golgi organization, 0008335=female germline ring canal stabilization, 0008360=regulation of cell shape, 0051127=positive regulation of actin nucleation, 0051125=regulation of actin nucleation, 0034314=Arp2/3 complex-mediated actin nucleation, 0030037=actin filament reorganization involved in cell cycle, 0030031=cell projection assembly, 0007015=actin filament organization, 0033627=cell adhesion mediated by integrin, 0000902=cell morphogenesis, 0007409=axonogenesis, 0007413=axonal fasciculation" "0045177=apical part of cell, 0045178=basal part of cell, 0031941=filamentous actin, 0031209=SCAR complex, 0005634=nucleus, 0005737=cytoplasm" "Scar, WAVE/SCAR, DmSCAR, CG4636, D-SCAR, DWave, l(2)k03107, Suppressor of cyclic AMP receptor, WAVE, l(2)k13811, dWAVE, suppressor of cAR, Dscar, SCAR/WAVE, suppressor of cAMP receptors, WASP family verprolin-homologous protein, wave, BEST:SD02991, Wave, unnamed, scar" "IPR028288=SCAR/WAVE family, IPR003124=WH2 domain" CG4636 16-Dec-15 2015_12 "ENSDARG00000024209(LOC100334712),ENSDARG00000060349(LOC100001221),ENSDARG00000062948(wasf3),ENSDARG00000059466(si:ch211-271b14.7)" WBGene00006958(wve-1) "ENSXETG00000003647(WASF2),ENSXETG00000021311(wasf1),ENSXETG00000004583(WASF3)" "ENSMUSG00000029636(Wasf3),ENSMUSG00000019831(Wasf1),ENSMUSG00000028868(Wasf2)" "ENSG00000132970(WASF3),ENSG00000112290(WASF1),ENSG00000158195(WASF2),ENSG00000188459" " embryonic stage | blastoderm , embryonic stage | late " neuron &&of embryonic central nervous system

"lethal,recessive,neuroanatomy defective,germline clone,cell migration defective,fertile,cell shape defective,sterile,dominant,visible,somatic clone,viable" "embryonic myoblast,microchaeta,dorsocentral bristle,myoblast,germline clone,RP2 motor neuron,actin cytoskeleton,nucleus | embryonic stage 4 | germline clone | non-rescuable maternal effect,ventral nerve cord,rescuable maternal effect,longitudinal connective,ventral nerve cord commissure,actin filament | embryonic stage 4 | germline clone | non-rescuable maternal effect,tract,actin cytoskeletonHml.PG,actin filament,nurse cell,nurse cell ring canal,eye,somatic clone,ommatidium,interommatidial bristle,intersegmental nerve,axon,neuromuscular junction & synapse,embryonic/larval somatic muscle,rhabdomere | adult stage | somatic clone,photoreceptor,outer photoreceptor cell,follicle cell,wing" FBgn0028360 Cdc7 Cdc7 kinase http://flybase.net/reports/FBgn0028360.html "FBgn0028359, FBgn0029883, FBgn0029884, FBgn0040156, FBgn0052742, FBgn0066815" protein_coding_gene "0005524=ATP binding, 0004702=receptor signaling protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0035173=histone kinase activity" "0007307=eggshell chorion gene amplification, 0045740=positive regulation of DNA replication, 0007113=endomitotic cell cycle, 0048102=autophagic cell death, 0016572=histone phosphorylation, 0006468=protein phosphorylation, 0035071=salivary gland cell autophagic cell death" "0005634=nucleus, 0031431=Dbf4-dependent protein kinase complex" "cdc7-related, CG32742, l(1)G0461, l(1)G0148, l(1)G0149, L(1)G0148, CG8656, anon-WO03040301.250, lethal (1) G0148, CG8655, CT25076, cdc7" "IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG32742 16-Dec-15 2015_12 ENSDARG00000023584(cdc7) YDL017W(CDC7) WBGene00016421(C34G6.5) ENSXETG00000023034(cdc7) ENSMUSG00000029283(Cdc7) ENSG00000097046(CDC7) "viable,fertile,lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,visible" "third instar larva,trichogen cell" FBgn0028292 ric8a ric8a http://flybase.net/reports/FBgn0028292.html FBgn0030115 protein_coding_gene "0001965=G-protein alpha-subunit binding, 0005085=guanyl-nucleotide exchange factor activity" "0040001=establishment of mitotic spindle localization, 0008105=asymmetric protein localization, 0055059=asymmetric neuroblast division, 0010004=gastrulation involving germ band extension, 0008356=asymmetric cell division, 0050821=protein stabilization, 0007163=establishment or maintenance of cell polarity" "0005737=cytoplasm, 0005829=cytosol" "l(1)G0397, ric-8, CG15797, ric-8a, Ric-8, RIC-8, DmRic8" "IPR008376=Synembryn, IPR019318=Guanine nucleotide exchange factor, Ric8, IPR016024=Armadillo-type fold" CG15797 16-Dec-15 2015_12 "ENSDARG00000005972(ric8b),ENSDARG00000007247(ric8a),ENSDARG00000052093,ENSDARG00000017579(LOC557783),ENSDARG00000016923" WBGene00004367(ric-8) "ENSXETG00000002868(BC063218.1),ENSXETG00000014801(RIC8B)" "ENSMUSG00000035620(Ric8b),ENSMUSG00000025485(Ric8)" "ENSG00000111785(RIC8B),ENSG00000177963(RIC8A)" "neuroanatomy defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,body color defective,germline clone,maternal effect" "eo neuron,ectopic,thecogen cell,spindle & external sensory organ precursor cell I,mesothoracic tergum,spindle | germline clone,gastrula embryo,germline clone,embryonic neuroblast,EL neuron,embryonic/first instar larval cuticle,maternal effect,spindle & embryonic neuroblast | maternal effect" FBgn0030011 Gë_5 Gë_5 http://flybase.net/reports/FBgn0030011.html protein_coding_gene 0003924=GTPase activity 0007186=G-protein coupled receptor signaling pathway 0005834=heterotrimeric G-protein complex "Gbeta 5, Gbetagamma, Gbeta5, G[[beta]], Gbeta, G[[beta5]], CG10763, G-protein beta 5" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR016346=Guanine nucleotide-binding protein, beta subunit, IPR001632=G-protein, beta subunit, IPR001680=WD40 repeat, IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site" CG10763 16-Dec-15 2015_12 "ENSDARG00000025845(gnb5a),ENSDARG00000055377(gnb5b)" YOR212W(STE4) WBGene00001680(gpb-2) ENSMUSG00000032192(Gnb5) ENSG00000069966(GNB5) FBgn0031821 KFase Kynurenine formamidase http://flybase.net/reports/FBgn0031821.html protein_coding_gene 0004061=arylformamidase activity 0019441=tryptophan catabolic process to kynurenine 0016272=prefoldin complex "kynurenine formamidase, CG9542" "IPR027519=Kynurenine formamidase, vertebrates/fungi-type, IPR013094=Alpha/beta hydrolase fold-3, IPR029058=Alpha/Beta hydrolase fold" CG9542 16-Dec-15 2015_12 ENSDARG00000030548(afmid) "WBGene00012866(Y45F10A.3),WBGene00017051(D2024.2)" ENSXETG00000003006(AFMID) ENSMUSG00000017718(Afmid) ENSG00000183077(AFMID) viable FBgn0038747 RhoGAP92B Rho GTPase activating protein at 92B http://flybase.net/reports/FBgn0038747.html protein_coding_gene "0005543=phospholipid binding, 0017124=SH3 domain binding, 0005096=GTPase activator activity" "1990255=subsynaptic reticulum organization, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0043547=positive regulation of GTPase activity, 0007274=neuromuscular synaptic transmission, 0007480=imaginal disc-derived leg morphogenesis, 0030837=negative regulation of actin filament polymerization, 0034613=cellular protein localization, 1900144=positive regulation of BMP secretion" "0005737=cytoplasm, 0031594=neuromuscular junction" "drich, CG4755, dRich, RhoGAP92B" "IPR000198=Rho GTPase-activating protein domain, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR018859=BAR domain-containing family, IPR008936=Rho GTPase activation protein, IPR004148=BAR domain" CG4755 16-Dec-15 2015_12 "ENSDARG00000010433,ENSDARG00000062263(zgc:172194)" WBGene00021324(Y34B4A.8) "ENSMUSG00000030766(Arhgap17),ENSMUSG00000033389(AU040829),ENSMUSG00000022436(Sh3bp1)" "ENSG00000140750(ARHGAP17),ENSG00000006740(ARHGAP44),ENSG00000100092(SH3BP1)" "viable,fertile,neuroanatomy defective,neurophysiology defective,lethal" "embryonic/larval neuromuscular junction,NMJ bouton,subsynaptic reticulum | third instar larval stage,type I bouton,presynaptic active zone | third instar larval stage,neuromuscular junction" FBgn0030077 CG15365 http://flybase.net/reports/FBgn0030077.html protein_coding_gene CG15365 16-Dec-15 2015_12 "ENSDARG00000058558,ENSDARG00000059134(LOC795227)" "ENSXETG00000017977(),ENSXETG00000015201(Q6DIS8_XENTR),ENSXETG00000006733()" "ENSG00000107816(LZTS2),ENSG00000088899(ProSAPiP1),ENSG00000061337(LZTS1),ENSG00000145911(N4BP3)" "lethal,recessive" FBgn0015299 Ssb-c31a Single stranded-binding protein c31A http://flybase.net/reports/FBgn0015299.html protein_coding_gene "0003697=single-stranded DNA binding, 0003713=transcription coactivator activity" "0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "PC4-like, CG8396, Ssb-C31a, p11, C31A" "IPR009044=ssDNA-binding transcriptional regulator, IPR003173=Transcriptional coactivator p15 (PC4)" CG8396 16-Dec-15 2015_12 "ENSDARG00000053446(zgc:109973),ENSDARG00000007720(sub1)" WBGene00011743(T13F2.2) ENSXETG00000027218(pc4) ENSMUSG00000022205(Sub1) ENSG00000113387(SUB1) " embryonic stage , oogenesis stage && adult stage | female " ovary

"viable,fertile,visible" trichogen cell FBgn0053906 His2B:CG33906 His2B:CG33906 http://flybase.net/reports/FBgn0053906.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33906 "IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33906 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053894 His2B:CG33894 His2B:CG33894 http://flybase.net/reports/FBgn0053894.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33894 "IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33894 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053820 His2A:CG33820 His2A:CG33820 http://flybase.net/reports/FBgn0053820.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33820 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A" CG33820 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0025879 Timp Tissue inhibitor of metalloproteases http://flybase.net/reports/FBgn0025879.html protein_coding_gene 0008191=metalloendopeptidase inhibitor activity "0007472=wing disc morphogenesis, 0060232=delamination, 0048526=imaginal disc-derived wing expansion, 0007426=tracheal outgrowth, open tracheal system, 0071711=basement membrane organization, 0007155=cell adhesion, 0042331=phototaxis, 0035202=tracheal pit formation in open tracheal system" "0030425=dendrite, 0005576=extracellular region" "CG6281, tissue inhibitor of metalloproteinases, Dtimp, timp, tissue inhibitor of metalloproteases, dTIMP, DTIMP, TIMP" "IPR008993=Tissue inhibitor of metalloproteinases-like, OB-fold, IPR027465=Proteinase inhibitor I35b (TIMP), C-terminal, IPR001820=Protease inhibitor I35 (TIMP), IPR001134=Netrin domain" CG6281 16-Dec-15 2015_12 "ENSDARG00000067833,ENSDARG00000061226(timp2a),ENSDARG00000053400,ENSDARG00000037806(LOC100148446)" "ENSXETG00000020206(Q5FVZ1_XENTR),ENSXETG00000011514(TIMP3)" "ENSMUSG00000017466(Timp2),ENSMUSG00000030317(Timp4),ENSMUSG00000020044(Timp3),ENSMUSG00000001131(Timp1)" "ENSG00000035862(TIMP2),ENSG00000157150(TIMP4),ENSG00000100234(TIMP3),ENSG00000102265(TIMP1)" pupal stage salivary gland

"partially lethal - majority live,cold sensitive,semi-fertile,phototaxis defective,lethal - all die before end of pupal stage,some die during embryonic stage,some die during larval stage,partially lethal - majority die,lethal,neuroanatomy defective,viable,visible" "wing,cold sensitive,wing vein,adult abdomen,embryonic/larval transverse connective | third instar larval stage,dorsal air sac primordium | third instar larval stage,wing disc | third instar larval stage,dorsal air sac,embryonic/larval dorsal trunk,embryonic/larval dorsal branch | third instar larval stage,dendritic arborizing neuron | P-stage,embryonic/larval transverse connective,ectopic | third instar larval stage,dorsal air sac primordium,tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,trachea,wing | pupal stage,leg | pupal stage,mesothoracic tergum,dorsal,basement membrane | pupal stageLsp2.PH,basement membrane | pupal stageUbx-lac1-Gal4" FBgn0034605 CG15661 http://flybase.net/reports/FBgn0034605.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG15661 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0003386 Shaw Shaker cognate w http://flybase.net/reports/FBgn0003386.html FBgn0040710 protein_coding_gene "0022843=voltage-gated cation channel activity, 0005249=voltage-gated potassium channel activity, 0005251=delayed rectifier potassium channel activity" "0030431=sleep, 0055085=transmembrane transport, 0006813=potassium ion transport, 0051260=protein homooligomerization" "0005886=plasma membrane, 0016021=integral component of membrane, 0008076=voltage-gated potassium channel complex" "Kv3, Kv3.1, Shaw2, shaw, CG2822, CG15419, dShaw, dShaw2" "IPR003968=Potassium channel, voltage dependent, Kv, IPR003091=Potassium channel, IPR015572=Voltage-dependent potassium channel protein Shaw, invertebrate, IPR000210=BTB/POZ domain, IPR005821=Ion transport domain, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR003974=Potassium channel, voltage dependent, Kv3, IPR011333=POZ domain, IPR028325=Voltage-gated potassium channel, IPR027359=Voltage-dependent channel, four helix bundle domain" CG2822 16-Dec-15 2015_12 "ENSDARG00000051852(LOC565419),ENSDARG00000032959,ENSDARG00000037933,ENSDARG00000061288(LOC799410),ENSDARG00000071134,ENSDARG00000055855" WBGene00008819(F14F11.1) "ENSXETG00000002027(),ENSXETG00000014391(KCNC1),ENSXETG00000023514()" "ENSMUSG00000058975(Kcnc1),ENSMUSG00000027895(Kcnc4),ENSMUSG00000062785(Kcnc3),ENSMUSG00000035681(Kcnc2)" "ENSG00000129159(KCNC1),ENSG00000131398(KCNC3),ENSG00000116396(KCNC4),ENSG00000166006(KCNC2)" " embryonic stage | late , pupal stage&&adult stage " "circadian behavior defective,circadian rhythm defective,viable,male,reduced,uncoordinated,chemical sensitive,eclosion defective,body size defective,body color defective,visible,female,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,locomotor rhythm defective,short lived" "wing,adult cuticle,motor neuron | larval stage" FBgn0051105 ppk22 pickpocket 22 http://flybase.net/reports/FBgn0051105.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "CG31105, FBgn0051105, pickpocket 22, ppk22" "IPR001873=Na+ channel, amiloride-sensitive" CG31105 16-Dec-15 2015_12 "WBGene00016063(C24G7.1),WBGene00016064(acd-1),WBGene00009073(F23B2.3),WBGene00020903(T28F2.7),WBGene00016066(C24G7.4),WBGene00017879(F28A12.1),WBGene00001465(flr-1)" viable FBgn0041150 hoe1 hoepel1 http://flybase.net/reports/FBgn0041150.html "FBgn0027606, FBgn0031647, FBgn0031648" protein_coding_gene "0005215=transporter activity, 0005302=L-tyrosine transmembrane transporter activity" "0055085=transmembrane transport, 0006810=transport" "0016020=membrane, 0016021=integral component of membrane" "hoepel, CG12787, CG2831, hoe, Hoe1, BcDNA:GH02636, CG11918" IPR004680=Citrate transporter-like domain CG12787 16-Dec-15 2015_12 ENSDARG00000061303(oca2) ENSXETG00000004157(OCA2) ENSMUSG00000030450(Oca2) ENSG00000104044(OCA2) "viable,fertile" DRSC00333 I 1.797465676 1.084175953 0.627557262 -0.549535869 -0.938719567 1.148764125 FBgn0051002 CG31002 http://flybase.net/reports/FBgn0051002.html FBgn0039845 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process 0012505=endomembrane system "CG15569, CG31002-PA" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG31002 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0262801 twr twisted bristles roughened eye http://flybase.net/reports/FBgn0262801.html "FBgn0011545, FBgn0004695, FBgn0026567, FBgn0027919" protein_coding_gene "0008236=serine-type peptidase activity, 0008233=peptidase activity" 0006465=signal peptide processing "0016021=integral component of membrane, 0005787=signal peptidase complex, 0012505=endomembrane system" "CG2358, EfW5, AF160889, Spase18-21, Ov15, Spase 18/21-subunit, BcDNA:GM04682, BG:DS00004.11, SPC 21-kDa-like, l(3)05614, l(3)84Aa, Spase18/21" "IPR015927=Peptidase S24/S26A/S26B/S26C, IPR001733=Peptidase S26B, IPR028360=Peptidase S24/S26, beta-ribbon domain, IPR019759=Peptidase S24/S26A/S26B, IPR019758=Peptidase S26A, signal peptidase I, conserved site, IPR019756=Peptidase S26A, signal peptidase I, serine active site" CG2358 16-Dec-15 2015_12 ENSDARG00000008936(sec11a) YIR022W(SEC11) WBGene00021844(Y54E10BR.5) "ENSXETG00000027226(BC077666.1),ENSXETG00000015293(sec11l1)" ENSMUSG00000024516(Sec11c) "ENSG00000166562(SEC11C),ENSG00000140612(SEC11A)" DRSC12491 E -0.739222115 -1.269300107 -1.631986371 0.713239402 1.140682198 0.395467034 FBgn0061209 His2B:CG17949 His2B:CG17949 http://flybase.net/reports/FBgn0061209.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0000786=nucleosome, 0005811=lipid particle" CG17949 "IPR000558=Histone H2B, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG17949 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" DRSC03757 IE -4.1418466 -4.75136865 -2.871391202 -8.721475461 -1.365366459 -1.42108456 FBgn0053842 His3:CG33842 His3:CG33842 http://flybase.net/reports/FBgn0053842.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33842 "IPR000164=Histone H3/CENP-A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33842 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053882 His2B:CG33882 His2B:CG33882 http://flybase.net/reports/FBgn0053882.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33882 "IPR000558=Histone H2B, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33882 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0083963 Nlg3 Neuroligin 3 http://flybase.net/reports/FBgn0083963.html "FBan0032465, FBgn0037507, FBgn0037508, FBgn0037509, FBgn0052465" protein_coding_gene "0004872=receptor activity, 0052689=carboxylic ester hydrolase activity, 0042043=neurexin family protein binding" "0022008=neurogenesis, 0007528=neuromuscular junction development, 0048488=synaptic vesicle endocytosis, 0007416=synapse assembly, 0006909=phagocytosis" "0045202=synapse, 0009986=cell surface, 0005887=integral component of plasma membrane" "DNlg3, CG18291, CG1062, neuroligin3, dnlg3, Drosokinin receptor, DNLG3, CG34127, CG32465, CG14597" "IPR002018=Carboxylesterase, type B, IPR019819=Carboxylesterase type B, conserved site, IPR029058=Alpha/Beta hydrolase fold" CG34127 16-Dec-15 2015_12 "ENSDARG00000062376(nlgn3b),ENSDARG00000062581(nlgn3a)" WBGene00013540(Y75B8A.3) "ENSXETG00000020891(NLGN3),ENSXETG00000021425(),ENSXETG00000001525(NLGN1),ENSXETG00000023971(NLGN2)" "ENSMUSG00000063887(Nlgn1),ENSMUSG00000031302(Nlgn3),ENSMUSG00000051790(Nlgn2)" "ENSG00000146938(NLGN4X),ENSG00000196338(NLGN3),ENSG00000165246(NLGN4Y),ENSG00000169760(NLGN1),ENSG00000169992(NLGN2)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0030775 CG9673 http://flybase.net/reports/FBgn0030775.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH81 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG9673 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" viable FBgn0029870 Marf Mitochondrial assembly regulatory factor http://flybase.net/reports/FBgn0029870.html FBgn0044368 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0007029=endoplasmic reticulum organization, 0007005=mitochondrion organization, 0008053=mitochondrial fusion, 0008344=adult locomotory behavior, 0034976=response to endoplasmic reticulum stress, 0034389=lipid particle organization, 0010636=positive regulation of mitochondrial fusion, 0090140=regulation of mitochondrial fission, 0019896=axon transport of mitochondrion, 0006697=ecdysone biosynthetic process, 0070584=mitochondrion morphogenesis" "0005741=mitochondrial outer membrane, 0005886=plasma membrane, 0016021=integral component of membrane, 0005740=mitochondrial envelope" "Mfn-2, Drosophila mitofusin, mitochondrial assembly regulatory factor, dmfn, MARF, Mfn, anon-WO0125274.3, Marf-1, dMFN, dMfn, marf, mitochondria assembly regulatory factor, CG3869, mitofusin/MARF, CG38869, Mitofusin, mfn2, mfn, mitofusin" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027094=Mitofusin family, IPR030381=Dynamin-type guanine nucleotide-binding (G) domain, IPR006884=Fzo/mitofusin HR2 domain" CG3869 16-Dec-15 2015_12 "ENSDARG00000011884(LOC100329462),ENSDARG00000005121(mfn1)" YBR179C(FZO1) WBGene00001509(fzo-1) "ENSXETG00000007258(mfn1),ENSXETG00000013049(MFN2)" "ENSMUSG00000029020(Mfn2),ENSMUSG00000027668(Mfn1)" "ENSG00000116688(MFN2),ENSG00000171109(MFN1)" "neuroanatomy defective,cell death defective,viable,visible,increased cell number,lethal - all die during second instar larval stage,stress response defective,lethal - all die during pupal stage,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,gravitaxis defective,progressive,lethal - all die before end of larval stage,some die during larval stage" "mitochondrionMef2.PR,mitochondrial cristaMef2.PR,adult brain,mitochondrionelav.PU,mitochondrionMhc.PW,trichogen cell,lamellocyte | third instar larval stage,mitochondrion | larval stagetub.PU,endoplasmic reticulum | larval stagetub.PU,mitochondrion | larval stageelav.PLu,endoplasmic reticulum | larval stageelav.PLu,mitochondrion | larval stageMef2.PR,sarcoplasmic reticulum | larval stageMef2.PR,adult heart,cardial cell,mitochondriontin.CëÓ4,mitochondrion | adult stagetin.CëÓ4,cardial cell | adult stage,eye,ommatidium,mitochondrion & dopaminergic neuronple.PF,indirect flight muscle" FBgn0267390 dop drop out http://flybase.net/reports/FBgn0267390.html "FBgn0036511, FBgn0262013, FBgn0004891" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0000287=magnesium ion binding, 0004672=protein kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0007032=endosome organization, 2000579=positive regulation of ATP-dependent microtubule motor activity, minus-end-directed, 0072659=protein localization to plasma membrane, 0009047=dosage compensation by hyperactivation of X chromosome, 0007030=Golgi organization, 0045793=positive regulation of cell size, 0007349=cellularization, 0007298=border follicle cell migration, 0035220=wing disc development, 0031887=lipid particle transport along microtubule" 0005737=cytoplasm "CG6498, MAST 205, MAST205" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR001478=PDZ domain, IPR023142=Microtubule-associated serine/threonine-protein kinase, pre-PK domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR015022=Microtubule-associated serine/threonine-protein kinase, domain, IPR008271=Serine/threonine-protein kinase, active site" CG6498 16-Dec-15 2015_12 WBGene00002192(kin-4) "ENSXETG00000003254(MAST2),ENSXETG00000021463(MAST4),ENSXETG00000012935(MAST3)" "ENSMUSG00000003810(Mast2),ENSMUSG00000053693(Mast1),ENSMUSG00000031833(Mast3),ENSMUSG00000034751(Mast4)" "ENSG00000105613(MAST1),ENSG00000086015(MAST2),ENSG00000069020(MAST4),ENSG00000099308(MAST3)" DRSC10655 IE 1.477105096 1.79529277 1.51488682 0.462284483 0.112895948 0.668104481 FBgn0053859 His2A:CG33859 His2A:CG33859 http://flybase.net/reports/FBgn0053859.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33859 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A" CG33859 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0264975 Nrg Neuroglian http://flybase.net/reports/FBgn0264975.html "FBgn0002968, FBgn0004669, FBgn0027311, FBgn0040142, FBgn0040165, FBgn0000874, FBgn0041750" protein_coding_gene 0005509=calcium ion binding "0007560=imaginal disc morphogenesis, 0045924=regulation of female receptivity, 0061343=cell adhesion involved in heart morphogenesis, 0048812=neuron projection morphogenesis, 0008366=axon ensheathment, 0019991=septate junction assembly, 0016319=mushroom body development, 0050808=synapse organization, 0008045=motor neuron axon guidance, 0048675=axon extension, 0035011=melanotic encapsulation of foreign target, 0007173=epidermal growth factor receptor signaling pathway, 0008049=male courtship behavior, 0048036=central complex development, 0021682=nerve maturation, 0035151=regulation of tube size, open tracheal system, 0007409=axonogenesis, 0060857=establishment of glial blood-brain barrier, 0008050=female courtship behavior, 0048813=dendrite morphogenesis, 0072499=photoreceptor cell axon guidance, 0007158=neuron cell-cell adhesion" "0035230=cytoneme, 0005919=pleated septate junction, 0016328=lateral plasma membrane, 0005918=septate junction, 0030175=filopodium, 0005886=plasma membrane" "nrg, CT4318, fs(1)M72, Nrg180, neuroglian, central brain deranged, l(1)G0099, ceb, female sterile(1)M72, unnamed, RA35, l(1)G0488, Nrg167, icebox, lethal (1) G0488, ibx, CG1634, Ngl, l(1)7Fa, NFASC, l(1)G0413, NRG" "IPR026966=Neurofascin/L1/NrCAM, C-terminal domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR013151=Immunoglobulin" CG1634 16-Dec-15 2015_12 "ENSDARG00000061099,ENSDARG00000006396(si:dkey-240a12.1),ENSDARG00000056910(LOC559590),ENSDARG00000007149(nadl1.2),ENSDARG00000015025(LOC100334780)" WBGene00002243(lad-2) "ENSXETG00000000719(L1CAM),ENSXETG00000015769(NRCAM),ENSXETG00000004390(NFASC)" "ENSMUSG00000020598(Nrcam),ENSMUSG00000026442(Nfasc),ENSMUSG00000031391(L1cam),ENSMUSG00000030077(Chl1)" "ENSG00000091129(NRCAM),ENSG00000163531(NFASC),ENSG00000198910(L1CAM),ENSG00000134121(CHL1)" " embryonic stage , embryonic stage | >=11-12 hr , embryonic stage | >=9 hr " " larval stage | third instar , embryonic stage | >=11-12 hr , oogenesis stage && adult stage | female , embryonic stage | >6 hr , embryonic stage | >=8 hr , embryonic stage | >=7 hr , embryonic stage " " epidermis &&of imaginal disc

, neuron &&of imaginal disc

, larval muscle system

, follicle cell

, neuron&&ofimaginal disc

, central nervous system | restricted

, embryonic peripheral nervous system | restricted

, embryonic/larval trachea

, embryonic/larval hindgut

, embryonic/larval salivary gland

" FBgn0010383 Cyp18a1 Cytochrome P450-18a1 http://flybase.net/reports/FBgn0010383.html FBgn0015708 protein_coding_gene "0008395=steroid hydroxylase activity, 0005506=iron ion binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding, 0009055=electron carrier activity" "0006694=steroid biosynthetic process, 0035074=pupation, 0035210=prepupal development, 0007480=imaginal disc-derived leg morphogenesis, 0007304=chorion-containing eggshell formation, 0055114=oxidation-reduction process, 0046344=ecdysteroid catabolic process, 0007552=metamorphosis" "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "CG6816, CYP18, CT20826, 181H6T, Cyp18, CytP450, Eig17-1, ESTS:181H6T, Cyt-P450-17C, CYP18A1-Dm, cyp18a1, Cytochrome P450 17C, 18a1, P-450, cyp18, Cyp18A1, P450" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG6816 16-Dec-15 2015_12 "ENSDARG00000026548(cyp2u1),ENSDARG00000056587(LOC563369),ENSDARG00000042982(cyp2j23),ENSDARG00000040424(LOC564107),ENSDARG00000042978(cyp2j25),ENSDARG00000042990(cyp2j21),ENSDARG00000042953(cyp2j30),ENSDARG00000038367(zgc:198195),ENSDARG00000038369(zgc:162815),ENSDARG00000018485(cyp2v2),ENSDARG00000022631(cyp2j22)" "WBGene00018262(cyp-33C3),WBGene00018413(cyp-33C4),WBGene00018261(cyp-33C5),WBGene00018260(cyp-33C7),WBGene00019967(cyp-33C8),WBGene00018264(cyp-33C6),WBGene00021710(cyp-33C11),WBGene00016697(cyp-33C2),WBGene00016860(cyp-33C9),WBGene00021168(cyp-33C12),WBGene00016686(cyp-33C1),WBGene00012448(cyp-33D3),WBGene00010589(cyp-33D1),WBGene00015709(cyp-33A1),WBGene00018334(cyp-33E2),WBGene00016092(cyp-33B1),WBGene00016768(cyp-33E1)" "ENSXETG00000021606(),ENSXETG00000026927(),ENSXETG00000026928(),ENSXETG00000011104(BC075265.1),ENSXETG00000011134(BC089693.1),ENSXETG00000011098(),ENSXETG00000009671(),ENSXETG00000027556(),ENSXETG00000026931(),ENSXETG00000008796(),ENSXETG00000019559(),ENSXETG00000018658(),ENSXETG00000002602(CYP2F1),ENSXETG00000027558(),ENSXETG00000027561(),ENSXETG00000026926(BC091704.1),ENSXETG00000011117(),ENSXETG00000027566(BC075418.1),ENSXETG00000027563(),ENSXETG00000027564(BC076922.1),ENSXETG00000009665(),ENSXETG00000018696(BC067993.1),ENSXETG00000025408(cyp2c8),ENSXETG00000008798(cyp2a13),ENSXETG00000012640(),ENSXETG00000004753(),ENSXETG00000017472(),ENSXETG00000001660(),ENSXETG00000019664(CYP2R1),ENSXETG00000016734(BC089736.1)" "ENSMUSG00000061740(Cyp2d22),ENSMUSG00000052520(Cyp2j5),ENSMUSG00000052914(Cyp2j6),ENSMUSG00000057088,ENSMUSG00000015224(Cyp2j9),ENSMUSG00000028571(Cyp2j13),ENSMUSG00000062185(Cyp2d34),ENSMUSG00000068086(Cyp2d9),ENSMUSG00000022445(Cyp2d26),ENSMUSG00000014372(Cyp2d10),ENSMUSG00000057138(Cyp2d12),ENSMUSG00000068085(Cyp2d11),ENSMUSG00000066097(Cyp2j11-ps),ENSMUSG00000068083(Cyp2d40),ENSMUSG00000058613,ENSMUSG00000052974(Cyp2f2),ENSMUSG00000067231(Cyp2c65),ENSMUSG00000025003(Cyp2c39),ENSMUSG00000067229(Cyp2c66),ENSMUSG00000066704(Cyp2b19),ENSMUSG00000032808(Cyp2c38),ENSMUSG00000049685(Cyp2g1),ENSMUSG00000040650(Cyp2b23),ENSMUSG00000067225(Cyp2c54),ENSMUSG00000025002(Cyp2c55),ENSMUSG00000060407(Cyp2a12),ENSMUSG00000003053(Cyp2c29),ENSMUSG00000025197(Cyp2c44),ENSMUSG00000054827(Cyp2c50),ENSMUSG00000042248(Cyp2c37),ENSMUSG00000074254(Cyp2a4),ENSMUSG00000030483(Cyp2b10),ENSMUSG00000030670(Cyp2r1),ENSMUSG00000005547(Cyp2a5),ENSMUSG00000040583(Cyp2b13),ENSMUSG00000040660(Cyp2b9),ENSMUSG00000025479(Cyp2e1),ENSMUSG00000060613(Cyp2c70),ENSMUSG00000025004(Cyp2c40),ENSMUSG00000074882(Cyp2c68),ENSMUSG00000062624(Cyp2c67),ENSMUSG00000078787(Cyp2t4),ENSMUSG00000040703(Cyp2s1)" "ENSG00000155016(CYP2U1),ENSG00000186104(CYP2R1),ENSG00000134716(CYP2J2)" "viable,fertile,lethal,developmental rate defective,melanotic mass phenotype,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "midgut | third instar larval stage,cuticle | third instar larval stage,metathoracic leg,adult head,embryonic dorsal epidermis,embryonic/first instar larval cuticle,embryonic head,embryonic/larval midgut primordium,denticle belt,leg | pupal stage,adult head | pupal stage" DRSC20235 I 1.04877799 1.78193124 -0.040245948 0.434405518 0.441191737 0.912267022 FBgn0032684 CG10178 http://flybase.net/reports/FBgn0032684.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG10178 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0266377 Pde8 Phosphodiesterase 8 http://flybase.net/reports/FBgn0266377.html "FBgn0034886, FBgn0250870" protein_coding_gene "0004115=3',5'-cyclic-AMP phosphodiesterase activity" "0007165=signal transduction, 0007498=mesoderm development, 0046058=cAMP metabolic process" "CG42241, pde8, CG5411, PDE8, CG45019" "IPR023088=3'5'-cyclic nucleotide phosphodiesterase, IPR000014=PAS domain, IPR002073=3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003607=HD/PDEase domain" CG45019 16-Dec-15 2015_12 WBGene00022389(pde-6) "ENSXETG00000017075(PDE8B),ENSXETG00000016104(PDE8A)" "ENSMUSG00000021684(Pde8b),ENSMUSG00000025584(Pde8a)" "ENSG00000113231(PDE8B),ENSG00000073417(PDE8A)" FBgn0038774 CG5023 http://flybase.net/reports/FBgn0038774.html protein_coding_gene 0003779=actin binding 0031032=actomyosin structure organization "IPR001997=Calponin/LIMCH1, IPR000557=Calponin repeat, IPR001715=Calponin homology domain, IPR003096=Smooth muscle protein/calponin" CG5023 16-Dec-15 2015_12 "ENSDARG00000033466(tagln2),ENSDARG00000045408(tagln),ENSDARG00000058394(zgc:66052),ENSDARG00000013831(tagln3)" YOR367W(SCP1) "ENSXETG00000018919(cnn3),ENSXETG00000027225(tagln2),ENSXETG00000016732(cnn1),ENSXETG00000003286(cnn2),ENSXETG00000003757(tagln)" "ENSMUSG00000026547(Tagln2),ENSMUSG00000022658(Tagln3),ENSMUSG00000032085(Tagln)" "ENSG00000158710(TAGLN2),ENSG00000144834(TAGLN3),ENSG00000149591(TAGLN)" viable DRSC15697 I 1.674850437 0.308748245 1.470077772 -0.794171845 -0.92061959 -0.53949205 FBgn0035978 UGP UGP http://flybase.net/reports/FBgn0035978.html protein_coding_gene 0003983=UTP:glucose-1-phosphate uridylyltransferase activity 0006011=UDP-glucose metabolic process 0005829=cytosol "UTP-G-1-P uridyiyltransferase, UGPase, CG4347, uridine diphosphate-glucose pyrophosphorylase, UDPGPP, UDP-glucose pyrophosphorylase" "IPR002618=UTP--glucose-1-phosphate uridylyltransferase family, IPR029044=Nucleotide-diphospho-sugar transferases, IPR016267=UTP--glucose-1-phosphate uridylyltransferase" CG4347 16-Dec-15 2015_12 "ENSDARG00000008200(ugp2b),ENSDARG00000005578(LOC555748)" YKL035W(UGP1) WBGene00010665(K08E3.5) ENSXETG00000013007(ugp2) ENSMUSG00000001891(Ugp2) ENSG00000169764(UGP2) viable FBgn0030672 CG9281 http://flybase.net/reports/FBgn0030672.html FBgn0045783 protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" 0043190=ATP-binding cassette (ABC) transporter complex BEST:LD38280 "IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9281 16-Dec-15 2015_12 "ENSDARG00000038785(abcf2),ENSDARG00000052331" YER036C(ARB1) WBGene00012097(abcf-2) ENSXETG00000014410(ABCF2) ENSMUSG00000028953(Abcf2) ENSG00000033050(ABCF2) "viable,fertile" FBgn0053871 His4:CG33871 His4:CG33871 http://flybase.net/reports/FBgn0053871.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33871 "IPR019809=Histone H4, conserved site, IPR009072=Histone-fold, IPR001951=Histone H4" CG33871 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0053883 His4:CG33883 His4:CG33883 http://flybase.net/reports/FBgn0053883.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0005634=nucleus, 0000786=nucleosome" CG33883 "IPR019809=Histone H4, conserved site, IPR001951=Histone H4, IPR009072=Histone-fold" CG33883 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0015402 ksr kinase suppressor of ras http://flybase.net/reports/FBgn0015402.html FBgn0011387 protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0019992=diacylglycerol binding, 0005524=ATP binding" "0046579=positive regulation of Ras protein signal transduction, 0006468=protein phosphorylation, 0008293=torso signaling pathway, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007476=imaginal disc-derived wing morphogenesis, 0007165=signal transduction, 0007265=Ras protein signal transduction, 0008595=anterior/posterior axis specification, embryo, 0007426=tracheal outgrowth, open tracheal system" "SR3-1, CG2899, EK3-1, Ksr-1, kinase suppressor of RAS, Kinase suppressor of Ras, Suppressor of Ras1 3-1, KSR, kinase suppressor of Ras85D, l(3)j5E2, EC3-1, dKsr, Ksr, KSR-1" "IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR025561=Kinase suppressor of RAS, SAM-like domain" CG2899 16-Dec-15 2015_12 "ENSDARG00000015867(si:ch211-240j18.3),ENSDARG00000068714(LOC100150814),ENSDARG00000030933(si:busm1-122b7.1)" WBGene00002239(ksr-1) ENSXETG00000021354(KSR1) ENSMUSG00000018334(Ksr1) "ENSG00000141068(KSR1),ENSG00000171435(KSR2)" "lethal,recessive,visible,dominant,germline clone,non-rescuable maternal effect,terminal phenotype,maternal effect,partially lethal - majority die" "wing,abdominal segment 8 & cephalopharyngeal skeleton | germ-line clone,abdominal segment 9 & cephalopharyngeal skeleton | germ-line clone,abdominal segment 10 & cephalopharyngeal skeleton | germ-line clone,abdominal segment 11 & cephalopharyngeal skeleton | germ-line clone,terminalia,germline clone,dorsal air sac primordium,somatic clone,A1-7 ventral acute muscle 2,precursor,eye photoreceptor cell,eye,photoreceptor cell,ommatidium,embryo,maternal effect,mesothoracic tergum" DRSC12379 IEK -1.488192508 -7.044356403 -2.511449496 -8.299114981 -4.329933676 -5.038492496 FBgn0053865 His2A:CG33865 His2A:CG33865 http://flybase.net/reports/FBgn0053865.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33865 "IPR002119=Histone H2A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33865 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0260945 Atg1 Autophagy-related 1 http://flybase.net/reports/FBgn0260945.html "FBgn0010715, FBgn0036313, FBgn0062118, FBgn0064136, FBgn0044321" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0016301=kinase activity, 0019894=kinesin binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity, 0032182=ubiquitin-like protein binding" "0050808=synapse organization, 0006979=response to oxidative stress, 0051124=synaptic growth at neuromuscular junction, 0035069=larval midgut histolysis, 0010508=positive regulation of autophagy, 0045819=positive regulation of glycogen catabolic process, 0010506=regulation of autophagy, 1902350=cellular response to chloroquine, 0001558=regulation of cell growth, 0032007=negative regulation of TOR signaling, 2000331=regulation of terminal button organization, 0050804=regulation of synaptic transmission, 0006914=autophagy, 0006897=endocytosis, 0016236=macroautophagy, 0014067=negative regulation of phosphatidylinositol 3-kinase signaling, 0045476=nurse cell apoptotic process, 0006468=protein phosphorylation, 0009267=cellular response to starvation, 0008088=axon cargo transport, 0045850=positive regulation of nurse cell apoptotic process, 0046777=protein autophosphorylation, 0034599=cellular response to oxidative stress, 0035096=larval midgut cell programmed cell death" 0034273=ATG1/UKL1 signaling complex "atg1, l(3)00305, dAtg1, dATG1, UNC 51-like, autophagy-specific gene1, ATG1, uncoordinated movement-51, unc-51, anon-WO0118547.287, Unc51, DmATG1, Unc-51, CG10967, unc51, autophagy-related gene 1, Pegarn, ULK1, Autophagy-specific gene 1, DK-4" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017184=Serine/threonine-protein kinase Unc-51, IPR022708=Serine/threonine-protein kinase, C-terminal, IPR008271=Serine/threonine-protein kinase, active site" CG10967 16-Dec-15 2015_12 ENSDARG00000062120(LOC100329702) YGL180W(ATG1) WBGene00006786(unc-51) "ENSMUSG00000004798(Ulk2),ENSMUSG00000029512(Ulk1)" "ENSG00000083290(ULK2),ENSG00000177169(ULK1)" FBgn0026314 Ugt35b UDP-glycosyltransferase 35b http://flybase.net/reports/FBgn0026314.html "FBgn0015836, FBgn0040258" protein_coding_gene "0016758=transferase activity, transferring hexosyl groups, 0008194=UDP-glycosyltransferase activity" 0006011=UDP-glucose metabolic process 0016021=integral component of membrane "DmeUgt35b, ugt35b, UDPGT2, UGT35b, CG6649, UDP-glycosyltransferase, unnamed, Ugt35B, AC 006491B, Ugt-35b, Ugt86Db" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG6649 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" adult stage " antennal segment 3

, adult head

, leg

" viable FBgn0030276 Dlic Dynein light intermediate chain http://flybase.net/reports/FBgn0030276.html "FBgn0027319, FBgn0028346" protein_coding_gene "0003777=microtubule motor activity, 0042623=ATPase activity, coupled, 0003774=motor activity" "0048477=oogenesis, 0008088=axon cargo transport, 0007067=mitotic nuclear division, 0048813=dendrite morphogenesis, 0007052=mitotic spindle organization, 0007018=microtubule-based movement, 0007409=axonogenesis, 0048814=regulation of dendrite morphogenesis, 0051028=mRNA transport, 0000226=microtubule cytoskeleton organization" "0005813=centrosome, 0005737=cytoplasm, 0005868=cytoplasmic dynein complex, 0005635=nuclear envelope, 0005875=microtubule associated complex, 0030286=dynein complex" "DyneinLC, dlic2, DLIC, dandelion clock, dynein light intermediate chain, Dynein light intermediate chain, dlic, D-LIC, l(1)G0065, CG1938, dynein light interme- diate chain, Dlic2, l(1)G0190, dynein light intermediate chain 2, DLIC2, Dlic" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR022780=Dynein family light intermediate chain, IPR008467=Dynein 1 light intermediate chain" CG1938 16-Dec-15 2015_12 "ENSDARG00000035924(dync1li2),ENSDARG00000036387(dync1li1)" WBGene00001007(dli-1) "ENSXETG00000005364(DYNC1LI1),ENSXETG00000011236(DYNC1LI2)" "ENSMUSG00000032435(Dync1li1),ENSMUSG00000035770(Dync1li2)" "ENSG00000144635(DYNC1LI1),ENSG00000135720(DYNC1LI2)" "neuroanatomy defective,somatic clone,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "dendrite & abdominal dorsal multidendritic neuron ddaC | somatic clone,axon & abdominal dorsal multidendritic neuron ddaC | somatic clone,Golgi apparatus & abdominal dorsal multidendritic neuron ddaC | somatic clone,egg chamber,germline clone,oocyte,nurse cell ring canal,class IV dendritic arborizing neuron,somatic clone,terminal tracheal cell" FBgn0261953 TfAP-2 Transcription factor AP-2 http://flybase.net/reports/FBgn0261953.html "FBgn0023417, FBgn0002411" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007480=imaginal disc-derived leg morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0002121=inter-male aggressive behavior, 0008049=male courtship behavior, 0007485=imaginal disc-derived male genitalia development, 0016348=imaginal disc-derived leg joint morphogenesis, 0048728=proboscis development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008344=adult locomotory behavior, 0008343=adult feeding behavior" 0005634=nucleus "stummelbein, dAP-2, AP-2, dTfap2, AP-2alpha, DAP-2, CG7807, dAP-2alpha, l(3)1215, lethal (3) 1215" "IPR004979=Transcription factor AP-2, IPR013854=Transcription factor AP-2, C-terminal" CG7807 16-Dec-15 2015_12 "ENSDARG00000059279(tfap2a),ENSDARG00000012667(tfap2b),ENSDARG00000008861,ENSDARG00000040606(tfap2c),ENSDARG00000023272(zgc:114196)" WBGene00019424(aptf-1) "ENSXETG00000027719(TFAP2E),ENSXETG00000001074(tfap2a),ENSXETG00000012025(tfap2c),ENSXETG00000021674(TFAP2B)" "ENSMUSG00000021359(Tcfap2a),ENSMUSG00000025927(Tcfap2b),ENSMUSG00000028640(Tcfap2c),ENSMUSG00000042477(Tcfap2e),ENSMUSG00000042596(Tcfap2d)" "ENSG00000137203(TFAP2A),ENSG00000008196(TFAP2B),ENSG00000087510(TFAP2C),ENSG00000116819(TFAP2E),ENSG00000008197(TFAP2D)" " larval stage | third instar , embryonic stage | stage 9-13 , embryonic stage | stage 12 , embryonic stage | stage 14 , embryonic stage | stage 14--larval stage , embryonic stage | stage 10-13 " " ventral nerve cord

, ventral thoracic disc

, procephalic neurogenic region | restricted

, eye-antennal disc | restricted

, embryonic protocerebrum

, brain | restricted

, larval optic lobe

, embryonic protocerebral neuromere

, procephalic neuroblast

" FBgn0005536 Mbs Myosin binding subunit http://flybase.net/reports/FBgn0005536.html "FBgn0010817, FBgn0011346, FBgn0011399, FBgn0028052, FBgn0028127, FBgn0036561, FBgn0036562, FBgn0052156, FBgn0061116, FBgn0062264" protein_coding_gene 0017018=myosin phosphatase activity "0007391=dorsal closure, 0008544=epidermis development, 0048675=axon extension, 0030725=germline ring canal formation, 0007560=imaginal disc morphogenesis, 0045314=regulation of compound eye photoreceptor development, 0035317=imaginal disc-derived wing hair organization, 0048477=oogenesis" "0045179=apical cortex, 0017023=myosin phosphatase complex, 0043296=apical junction complex, 0045177=apical part of cell" "lethal (3) S057306b, Myosin phosphatase, lethal (3) S095304, myosin phosphatase target subunit, DMBS, mbs, CG5600, Myosin phosphatase-binding subunit, l(3)j7A1, 0953/04, CG5891, l(3)S057306, DMbs, l(3)S057306b, MBS, CG32156, l(3)j3B4, l(3)72Dd, MLC-phosphatase, lethal(3)72Dd, l(3)S005331b, myosin binding subunit, Mypt, 0573/06, l(3)S095304, DMYPT, l(3)03802" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG32156 16-Dec-15 2015_12 ENSDARG00000010784(ppp1r12a) YMR068W(AVO2) WBGene00003196(mel-11) ENSXETG00000021468(PPP1R12A) "ENSMUSG00000019907(Ppp1r12a),ENSMUSG00000073557(Ppp1r12b)" "ENSG00000058272(PPP1R12A),ENSG00000077157(PPP1R12B)" "neuroanatomy defective,somatic clone,lethal,recessive,germline clone,maternal effect,polyphasic,female sterile,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile,viable,visible,cell polarity defective,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,axis specification defective" "axon | somatic clone | third instar larval stage,embryonic/first instar larval cuticle,embryonic leading edge cell,egg,germline clone,nurse cell ring canal,ovariole,ring canal,nurse cell,centriole | germline clone,wing disc,somatic clone,wing,dorsal,dorsal hair,eye disc,oocyte,morphogenetic furrow,germline cyst,imaginal disc,wing hair,adult abdomen,embryonic/larval epidermis,anterior embryonic/larval midgut | embryonic stage 16,embryonic proventriculus | embryonic stage 16,anterior embryonic/larval midgut | embryonic stage 15,embryonic proventriculus | embryonic stage 15,anterior embryonic/larval midgut | embryonic stage 17,embryonic proventriculus | embryonic stage 17,eye" FBgn0035414 CG14965 http://flybase.net/reports/FBgn0035414.html FBgn0019884 protein_coding_gene 0003676=nucleic acid binding "dmLD47616p, anon-63BC-T3, 63BC-T3, ORF1" "IPR006612=Zinc finger, C2CH-type" CG14965 16-Dec-15 2015_12 "ENSG00000041988(THAP3),ENSG00000173451(THAP2),ENSG00000131931(THAP1)" viable FBgn0263896 l(3)E47 http://flybase.net/reports/FBgn0263896.html gene 16-Dec-15 2015_12 "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0053875 His4:CG33875 His4:CG33875 http://flybase.net/reports/FBgn0053875.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33875 "IPR009072=Histone-fold, IPR019809=Histone H4, conserved site, IPR001951=Histone H4" CG33875 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0000042 Act5C Actin 5C http://flybase.net/reports/FBgn0000042.html "FBgn0025223, FBgn0026673, FBgn0026683, FBgn0026712, FBgn0027215, FBgn0027255, FBgn0027284, FBgn0027327, FBgn0028278, FBgn0040144, FBgn0040204" protein_coding_gene 0005200=structural constituent of cytoskeleton "0006909=phagocytosis, 0000281=mitotic cytokinesis, 0032507=maintenance of protein location in cell, 0006338=chromatin remodeling, 0007291=sperm individualization, 0016319=mushroom body development, 0035148=tube formation, 0007010=cytoskeleton organization, 0002121=inter-male aggressive behavior" "0005811=lipid particle, 0005884=actin filament, 0005875=microtubule associated complex, 0031011=Ino80 complex, 0035060=brahma complex" "act 5C, l(1)G0420, l(1)G0010, anon-fast-evolving-2D2, ACT1_DROME, beta-actin, actin, Act5, actin 5C, T11, l(1)G0245, l(1)G0009, l(1)G0117, ACT, ACTIN 5C, Actin5c, Ac5C, cellular cytoskeletal beta-actin, l(1)G0486, actin A1, actin5c, A, CG4027, Act5c, Dm-actin5C, M32055, Act, ACT5C, l(1)G0079, 5C actin, l(1)G0177, actin 5 C, Actin 5c, Actin5C, act5C, Act-5C, BAP47, Actin, chrX:5748184..5748304, A4V404_DROME, G-actin, l(1)G0025, F-actin, beta-actin/Bap47, Actin/BAP47, cyt5C, Bap47, actin5C, anon-EST:fe2D2, act, l(1)G0330" "IPR004000=Actin family, IPR004001=Actin, conserved site, IPR020902=Actin/actin-like conserved site" CG4027 16-Dec-15 2015_12 "ENSDARG00000037746(bactin1),ENSDARG00000037870(bactin2)" YFL039C(ACT1) "WBGene00000066(act-4),WBGene00000065(act-3),WBGene00000064(act-2)" "ENSXETG00000027641(actg1),ENSXETG00000025116(BC068217.1)" ENSMUSG00000029580(Actb) "ENSG00000184009(ACTG1),ENSG00000075624(ACTB)" " embryonic stage , embryonic stage | early " " embryonic central nervous system

, ventral nerve cord

,

ubiquitous , posterior embryonic/larval midgut

, subesophageal ganglion

, supraesophageal ganglion

, anterior embryonic/larval midgut

" "lethal - all die before end of larval stage,recessive,some die during larval stage,viable,fertile,behavior defective,lethal,partially lethal - majority die,visible,somatic clone,mitotic cell cycle defective" "head bristle,macrochaeta,mushroom body alpha-lobe,adult mushroom body alpha'-lobe,arista,trichome,eye,anterior crossvein,somatic clone,ectopic,germline cyst,border follicle cell,border follicle cell & filopodium,trichogen cell" DRSC17723 I -1.742969601 -2.287417467 0.00295251 -0.815609835 1.339159869 1.195704438 FBgn0261014 TER94 TER94 http://flybase.net/reports/FBgn0261014.html "FBgn0024923, FBgn0010554, FBgn0015484, FBgn0019709, FBgn0019722, FBgn0025353, FBgn0027618, FBgn0064213, FBgn0082213, FBgn0082214, FBgn0024280" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0016887=ATPase activity, 0016787=hydrolase activity" "0048813=dendrite morphogenesis, 0007317=regulation of pole plasm oskar mRNA localization, 0046598=positive regulation of viral entry into host cell, 0045451=pole plasm oskar mRNA localization, 0043525=positive regulation of neuron apoptotic process, 0007029=endoplasmic reticulum organization, 0098586=cellular response to virus, 0042052=rhabdomere development, 0006511=ubiquitin-dependent protein catabolic process, 0000226=microtubule cytoskeleton organization, 0007279=pole cell formation, 0043523=regulation of neuron apoptotic process, 0006508=proteolysis, 0016320=endoplasmic reticulum membrane fusion, 0007030=Golgi organization, 0008104=protein localization, 0008103=oocyte microtubule cytoskeleton polarization, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process" "0005811=lipid particle, 0005737=cytoplasm, 0005634=nucleus, 0043186=P granule, 0045169=fusome, 0005886=plasma membrane, 0000502=proteasome complex, 0005875=microtubule associated complex, 0031965=nuclear membrane, 0005783=endoplasmic reticulum" "anon-WO2004063362.65, ter94, BcDNA.GM02885, Transitional Endoplasmic Reticulum 94, DmTER94, 22.26, l(2)03775, Apple, CDC48, anon-WO2004063362.67, transitional endoplasmic reticulum ATPase, pTER94, dmTERA, Valosin-containing protein, I, dVCP, VCP ATPase, Transitional endoplasmic reticulum 94, valosin-containing protein, 7.12, l(2)46CFf, BcDNA:GM02885, CG2331, Valosin-Containing Protein, vcp, Complementation group I, dvcp, Tera, l(2)46CFs, VCP/p97, unnamed, Transitional endoplasmic reticulum ATPase, dTERA, Vcp, p97 ATPase, Ter94, p97, Valosin containing protein, cdc48, VCP, l(2)46Ch" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR009010=Aspartate decarboxylase-like domain, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR004201=CDC48, domain 2, IPR005938=AAA ATPase, CDC48 family, IPR003338=CDC48, N-terminal subdomain, IPR015415=Vps4 oligomerisation, C-terminal, IPR029067=CDC48 domain 2-like" CG2331 16-Dec-15 2015_12 "ENSDARG00000020008(vcp),ENSDARG00000011983(zgc:136908)" YDL126C(CDC48) "WBGene00008053(cdc-48.2),WBGene00007352(cdc-48.1)" ENSXETG00000025788(vcp) ENSMUSG00000028452(Vcp) ENSG00000165280(VCP) adult stage && oogenesis stage " ovary

, follicle cell

, oocyte

, germarium region 1

, nurse cell

, cystoblast

, cystocyte

" " adult stage | female , adult stage , adult stage && oogenesis stage , embryonic stage && pupal stage && adult stage , adult stage | male , oogenesis stage | stage S1 && adult stage | female " " nurse cell

, mushroom body

, mushroom body alpha-lobe

, antennal glomerulus

, cystocyte

, calyx of mushroom body

, oocyte

, mushroom body beta-lobe

, germarium region 2b

, spermatozoon

, ellipsoid body

, germarium

, fusome

, egg chamber

" DRSC27600 K -0.088808526 -0.421252864 -0.558801738 0.412005237 2.057561479 2.464984974 FBgn0053903 His4:CG33903 His4:CG33903 http://flybase.net/reports/FBgn0053903.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33903 "IPR009072=Histone-fold, IPR019809=Histone H4, conserved site, IPR001951=Histone H4" CG33903 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0015286 Rala Ras-like protein A http://flybase.net/reports/FBgn0015286.html "FBgn0025241, FBgn0027285, FBgn0028308, FBgn0040134" protein_coding_gene "0005525=GTP binding, 0005515=protein binding, 0030165=PDZ domain binding, 0003924=GTPase activity" "0046329=negative regulation of JNK cascade, 0045087=innate immune response, 0007298=border follicle cell migration, 0008593=regulation of Notch signaling pathway, 0050829=defense response to Gram-negative bacterium, 0007391=dorsal closure, 0007464=R3/R4 cell fate commitment, 0045824=negative regulation of innate immune response, 0022604=regulation of cell morphogenesis, 0007265=Ras protein signal transduction" 0005886=plasma membrane "Dm RalA, D-RalA, RalA, anon-EST:fe1H4, DRala, dRal, Ras-related protein, Drala, ralA, RALA, DRal, Ral-a, CG2849, l(1)G0174, P48555, l(1)G0501, Ral, ral, l(1)G0373, 24639550, Dral, DralA, anon-fast-evolving-1H4" "IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020849=Small GTPase superfamily, Ras type" CG2849 16-Dec-15 2015_12 "ENSDARG00000016253(zgc:92116),ENSDARG00000045463(rala),ENSDARG00000040778(ralba),ENSDARG00000041425(ralbb)" WBGene00021811(ral-1) ENSXETG00000013108(rala) "ENSMUSG00000008859(Rala),ENSMUSG00000004451(Ralb)" "ENSG00000006451(RALA),ENSG00000144118(RALB)" "viable,visible,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal,lethal - all die before end of P-stage,some die during P-stage,some die during pharate adult stage,increased cell death,somatic clone,male sterile,planar polarity defective,decreased cell size,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,microchaeta,macrochaeta,eye,wing vein,chaeta,embryonic/larval salivary gland,border follicle cell,somatic clone,ommatidium,head bristle,humeral bristle,chaeta & mesothoracic tergum,wing blade,eye photoreceptor cell,ommatidial precursor cluster,dorsal closure embryo,embryonic/first instar larval cuticle,embryonic epidermis,anterior,dorsal,crossvein,wing hair,scutum & trichome69B,scutum & macrochaeta69B,scutum & macrochaeta-537.4,scutum & microchaeta-537.4,scutum & macrochaeta & tormogen cell-537.4,scutum & microchaeta & tormogen cell-537.4,scutum & macrochaeta & trichogen cell-537.4,scutum & microchaeta & trichogen cell-537.4,supernumerary" FBgn0053821 His3:CG33821 His3:CG33821 http://flybase.net/reports/FBgn0053821.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33821 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33821 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0085747 CR40572 http://flybase.net/reports/FBgn0085747.html FBan0040572 rRNA_gene CR40572 16-Dec-15 2015_12 FBgn0053845 His3:CG33845 His3:CG33845 http://flybase.net/reports/FBgn0053845.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33845 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33845 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0263023 CG43318 http://flybase.net/reports/FBgn0263023.html "FBan0014876, FBgn0038368" protein_coding_gene CG14876 CG43318 16-Dec-15 2015_12 FBgn0261046 Dscam3 Down syndrome cell adhesion molecule 3 http://flybase.net/reports/FBgn0261046.html "FBgn0250794, FBgn0051190, FBgn0038513, FBgn0038514" protein_coding_gene 0042802=identical protein binding "0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007155=cell adhesion" "0005887=integral component of plasma membrane, 0005886=plasma membrane" "Dscam-like, CG8106, CG31190, CT33960, CG12536" "IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype" CG31190 16-Dec-15 2015_12 ENSXETG00000003741(DSCAML1) FBgn0014272 l(2)talc "lethal (2) tumorous antennal, labial, clypeo-labral imaginal discs" http://flybase.net/reports/FBgn0014272.html gene 0007446=imaginal disc growth "l(2)k10622, l(2)106/22" 16-Dec-15 2015_12 "hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "eye-antennal disc,labial disc" FBgn0021908 l(2)k11537 lethal (2) k11537 http://flybase.net/reports/FBgn0021908.html gene 16-Dec-15 2015_12 "partially lethal - majority die,lethal,recessive" FBgn0067368 l(2)NC204 lethal (2) NC204 http://flybase.net/reports/FBgn0067368.html gene NC204 16-Dec-15 2015_12 "lethal,recessive" FBgn0029880 CG14443 http://flybase.net/reports/FBgn0029880.html protein_coding_gene "0005524=ATP binding, 0003676=nucleic acid binding, 0004386=helicase activity" cg14443 "IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal" CG14443 16-Dec-15 2015_12 viable FBgn0037882 CG17187 http://flybase.net/reports/FBgn0037882.html FBgn0064881 protein_coding_gene "0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome BcDNA:RE47242 IPR001623=DnaJ domain CG17187 16-Dec-15 2015_12 ENSDARG00000026561 WBGene00001040(dnj-22) ENSXETG00000021559(TNeu051m14.1) ENSMUSG00000034278(Dnajc17) ENSG00000104129(DNAJC17) "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053862 His2A:CG33862 His2A:CG33862 http://flybase.net/reports/FBgn0053862.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33862 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR002119=Histone H2A" CG33862 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0053856 His2A:CG33856 His2A:CG33856 http://flybase.net/reports/FBgn0053856.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33856 "IPR002119=Histone H2A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33856 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0003079 Raf Raf oncogene http://flybase.net/reports/FBgn0003079.html FBgn0040149 protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0005057=receptor signaling protein activity, 0005515=protein binding" "0007369=gastrulation, 0046579=positive regulation of Ras protein signal transduction, 0007552=metamorphosis, 0007362=terminal region determination, 0008284=positive regulation of cell proliferation, 0007472=wing disc morphogenesis, 0035309=wing and notum subfield formation, 0007283=spermatogenesis, 0070374=positive regulation of ERK1 and ERK2 cascade, 0046777=protein autophosphorylation, 0007476=imaginal disc-derived wing morphogenesis, 0035171=lamellocyte differentiation, 0030641=regulation of cellular pH, 0008293=torso signaling pathway, 0009267=cellular response to starvation, 0007428=primary branching, open tracheal system, 0040014=regulation of multicellular organism growth, 0008586=imaginal disc-derived wing vein morphogenesis, 2001234=negative regulation of apoptotic signaling pathway, 0042386=hemocyte differentiation, 0002168=instar larval development, 0016242=negative regulation of macroautophagy, 0030097=hemopoiesis, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0051726=regulation of cell cycle, 0046534=positive regulation of photoreceptor cell differentiation, 0007298=border follicle cell migration, 0007173=epidermal growth factor receptor signaling pathway, 0007165=signal transduction" "0005737=cytoplasm, 0005886=plasma membrane" "l(1)ph, D-raf, raf-1, raf1, lincRNA.937, ph1, l(1)2Fe, Draf, ph, Raf1, Raf, Polehole, Pole Hole, phl, pole-hole, l(1)polehole/draf, Draf-1, Raf/phl, l(1)polehole, l(1)phl, pole hole, l(1)G0475, Pole hole, raf-like-oncogene-1, D-Raf, D-raf1, CG2845, RAF, polehole, Draf1, Phl, DRaf1, DRaf, dRaf, rafl, l(1)pole hole, D-RAF, C110, draf, raf, 11-29, EG:BACH48C10.3, l(1)raf" "IPR017441=Protein kinase, ATP binding site, IPR003116=Raf-like Ras-binding, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR029071=Ubiquitin-related domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain" CG2845 16-Dec-15 2015_12 "ENSDARG00000017661(braf),ENSDARG00000054533(araf),ENSDARG00000059406" "ENSXETG00000004845(BRAF),ENSXETG00000020163(RAF1)" "ENSMUSG00000002413(Braf),ENSMUSG00000000441(Raf1),ENSMUSG00000001127(Araf)" "ENSG00000157764(BRAF),ENSG00000132155(RAF1),ENSG00000078061(ARAF)" " embryonic stage , adult stage && oogenesis stage " oocyte

embryonic stage "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,increased cell death,visible,heat sensitive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,germline clone,terminal phenotype,partially,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage,rescuable maternal effect,mitotic cell cycle defective,somatic clone,female sterile,dominant,poor,male,lethal - all die before end of P-stage,some die during pharate adult stage,homeotic,endomitotic cell cycle defective,small body,reduced,partially lethal - majority live,large body,cell size defective,developmental rate defective,cell growth defective,tumorigenic,increased cell size,neuroanatomy defective,increased cell number,hyperplasia,conditional,cell polarity defective,decreased cell number" "photoreceptor cell R6,ommatidium,eye,thorax,eye photoreceptor cell,photoreceptor cell R7,cone cell,midgut,embryo,wing vein,heat sensitive,ectopic,dorsal appendage,follicle cell,maternal effect,chorion | maternal effect | heat sensitive,wing disc,anterior compartment,posterior compartment,wing,leg,somatic clone,cephalopharyngeal skeleton,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,abdominal 1 ventral denticle belt,posterior,germline clone,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,imaginal disc,testis,spermatocyte,fusome,salivary gland imaginal ring,mitotic cell cycle,embryonic epidermis,embryonic head,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,stage 5 embryo,anterior,photoreceptor cell R8,supernumerary,ventral furrow,central nervous system,peripheral nervous system,chordotonal organ,lateral,ventral midline,dorsal,labral segment,dorsal bridge,embryonic/larval pharynx,hypostomal sclerite,embryonic/larval brain,embryonic/larval optic lobe,embryonic/larval labral segment sense organ,rescuable maternal effect,embryonic/first instar larval cuticle,lamellocyte,hemocyte,filzkorper,abdominal 11 anal tuft,anal pad,spermatocyte fusome,pole cell,salivary gland common duct primordium,gastrula embryo,A1-7 ventral acute muscle 2,precursor,embryonic/larval hemocyte,macrochaeta,photoreceptor cell,ocular segment,telson,bract,mitotic cell cycle | rescuable maternal effect,non-rescuable maternal effect,rhabdomere,interommatidial bristle,morphogenetic furrow,antenna,enterocyte,intestinal stem cell,wing vein L3,adult heart,adult heart muscle,myofilamenttin.CëÓ4,cardial cell,nuclear chromosometin.CëÓ4,embryonic/larval ganglionic branch,trichome,femur,bract | ectopic & mesothoracic tergumhs.PB,bract | ectopic & wing | dorsalhs.PB,bract | ectopic & costal veinhs.PB,bract | ectopic & wing hinge | dorsalhs.PB,bract | ectopic & halterehs.PB,bract | ectopic & adult external prothoraxhs.PB,bract | ectopic & aristahs.PB,bract | ectopic & genahs.PB,wing sensillum,wing vein L5,wing margin,wing vein L4,mesothoracic tergum,anterior supraalar bristle,posterior supraalar bristle,dorsocentral bristle,macrochaeta & mesothoracic tergum179b,hindgut visceral muscle primordium,tracheal branch primordium,mesothoracic tergum & macrochaeta | ectopic-C253,eye-antennal disc,midline glial cell,mitotic cell cycle | somatic clone,chorion | maternal effect55B,bouton,rhabdomere | supernumeraryhs.2sev,wing cell,adult midgut precursor cell | third instar larval stage,adult Malpighian tubule,conditional,adult midgut precursor cell | prepupal stage P1" DRSC18821 IEK -0.544319869 -2.502655391 -0.614568601 -5.385833486 -1.33915694 -1.784098679 FBgn0040099 lectin-28C lectin-28C http://flybase.net/reports/FBgn0040099.html FBgn0031956 protein_coding_gene "0005534=galactose binding, 0030246=carbohydrate binding" "AC 004723A, CG7106, AC004723a, Lectin28C" "IPR016187=C-type lectin fold, IPR016186=C-type lectin-like, IPR001304=C-type lectin" CG7106 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000040963(Asgr2),ENSMUSG00000020884(Asgr1),ENSMUSG00000000318(Clec10a),ENSMUSG00000040950(Mgl2),ENSMUSG00000036103(Colec12),ENSMUSG00000034783(Cd207)" "ENSG00000118004(COLEC11),ENSG00000220191,ENSG00000165471(MBL2),ENSG00000184374(COLEC10),ENSG00000133661(SFTPD),ENSG00000182314,ENSG00000122854,ENSG00000122852(SFTPA1),ENSG00000185303(SFTPA2)" viable FBgn0261705 CG42741 http://flybase.net/reports/FBgn0261705.html "FBgn0034810, FBgn0085238" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0006355=regulation of transcription, DNA-templated, 0022008=neurogenesis" 0005634=nucleus "CG9895, CG34209" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG42741 16-Dec-15 2015_12 "ENSDARG00000015312(klf12a),ENSDARG00000032197(klf12b),ENSDARG00000060661(si:ch211-208m1.2)" "YLR131C(ACE2),YDR146C(SWI5)" WBGene00013970(ZK337.2) "ENSXETG00000005739(klf4),ENSXETG00000002075(TGas051p13.1),ENSXETG00000001058(TNeu106n15.1)" FBgn0250789 ë±-Spec ë± Spectrin http://flybase.net/reports/FBgn0250789.html "FBgn0026231, FBgn0064128, FBgn0025219, FBgn0002180, FBgn0003470" protein_coding_gene "0008017=microtubule binding, 0005516=calmodulin binding, 0008092=cytoskeletal protein binding, 0005509=calcium ion binding, 0003779=actin binding" "0045478=fusome organization, 0042062=long-term strengthening of neuromuscular junction, 0048790=maintenance of presynaptic active zone structure, 0016199=axon midline choice point recognition, 0016337=single organismal cell-cell adhesion, 0008360=regulation of cell shape, 0007308=oocyte construction, 0030727=germarium-derived female germ-line cyst formation, 0002168=instar larval development, 0030707=ovarian follicle cell development, 0030721=spectrosome organization, 0007010=cytoskeleton organization, 0007026=negative regulation of microtubule depolymerization, 0007294=germarium-derived oocyte fate determination, 0050807=regulation of synapse organization, 0007274=neuromuscular synaptic transmission, 0007009=plasma membrane organization, 0048134=germ-line cyst formation, 0007293=germarium-derived egg chamber formation, 0007417=central nervous system development, 0060429=epithelium development, 0008302=female germline ring canal formation, actin assembly" "0005794=Golgi apparatus, 0005938=cell cortex, 0005886=plasma membrane, 0008091=spectrin, 0031594=neuromuscular junction, 0045169=fusome, 0005856=cytoskeleton, 0016323=basolateral plasma membrane, 0045170=spectrosome, 0005811=lipid particle" "aSpc 3A9, alphaSpectrin, alpha-spec, l(3)dre3, alpha-spectrin II, klotzchen, alpha-Spect, alpha-Spc, alphaSp, alpha-Spec, alphaSpec, alpha spectrin, alpha, Spectrin, alpha-Sp, Spec, l(3)04276, 3A9, spectrin, l(3)62Bd, alpha-Spe, alpha Spectrin, FCP-B, alpha-SPECTRIN, alpha-spectrin, l(3)alpha-Spec, dre3, FBtr0072789, Alpha Spectrin, alpha-Spectrin, CG1977, klo, unnamed, Alpha-spectrin, alfa-Spec, anon-EST:fe2E2, anon-fast-evolving-2E2, alpha-SPEC" "IPR011992=EF-hand domain pair, IPR018159=Spectrin/alpha-actinin, IPR018247=EF-Hand 1, calcium-binding site, IPR013315=Spectrin alpha chain, SH3 domain, IPR001452=SH3 domain, IPR002017=Spectrin repeat, IPR002048=EF-hand domain, IPR014837=EF-hand, Ca insensitive" CG1977 16-Dec-15 2015_12 ENSDARG00000019231(spna2) WBGene00004951(spc-1) ENSXETG00000015800(SPTBN5) ENSMUSG00000057738(Spna2) ENSG00000197694(SPTAN1) adult stage germarium && follicle cell

FBgn0053824 His3:CG33824 His3:CG33824 http://flybase.net/reports/FBgn0053824.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33824 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33824 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0243512 puc puckered http://flybase.net/reports/FBgn0243512.html "FBgn0011600, FBgn0004210, FBgn0011369" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0017017=MAP kinase tyrosine/serine/threonine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0004721=phosphoprotein phosphatase activity, 0008579=JUN kinase phosphatase activity" "0043066=negative regulation of apoptotic process, 0046528=imaginal disc fusion, 0030036=actin cytoskeleton organization, 0009306=protein secretion, 0006470=protein dephosphorylation, 0046844=micropyle formation, 0034599=cellular response to oxidative stress, 0070303=negative regulation of stress-activated protein kinase signaling cascade, 0007254=JNK cascade, 0008340=determination of adult lifespan, 0001736=establishment of planar polarity, 0050778=positive regulation of immune response, 0046329=negative regulation of JNK cascade, 0008360=regulation of cell shape, 0071907=determination of digestive tract left/right asymmetry, 0030707=ovarian follicle cell development, 0048749=compound eye development, 0007391=dorsal closure, 0007561=imaginal disc eversion, 0008362=chitin-based embryonic cuticle biosynthetic process, 0008544=epidermis development, 0016318=ommatidial rotation, 0007298=border follicle cell migration, 0007015=actin filament organization, 0042060=wound healing, 0010389=regulation of G2/M transition of mitotic cell cycle, 0046529=imaginal disc fusion, thorax closure, 0000188=inactivation of MAPK activity, 0007396=suture of dorsal opening, 0048615=embryonic anterior midgut (ectodermal) morphogenesis, 0006979=response to oxidative stress, 0046843=dorsal appendage formation, 0007422=peripheral nervous system development" "0005794=Golgi apparatus, 0005783=endoplasmic reticulum" "0238/03, 1351/08, PUC/MKP, vco, l(3)84Eh, lethal (3) j4E1, CG7850, Velcro, l(3)j4E1, JNK-DSP, Puckered, Puc, PUC, hrt, l(3)A251.1, velcro, Jun N-terminal kinase dual-specificity phosphatase, hearty" "IPR020422=Dual specificity protein phosphatase domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR024950=Dual specificity phosphatase, IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site" CG7850 16-Dec-15 2015_12 WBGene00006923(vhp-1) "ENSMUSG00000037887(Dusp8),ENSMUSG00000030203(Dusp16)" "ENSG00000184545(DUSP8),ENSG00000111266(DUSP16)" " embryonic stage , embryonic stage | 4-8 hr " epidermis | dorsal

DRSC17034 IEK 0.109788573 -3.882864057 -2.988694496 -2.061521113 1.369600918 1.657226478 FBgn0003410 sina seven in absentia http://flybase.net/reports/FBgn0003410.html FBgn0025204 protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0043621=protein self-association, 0004842=ubiquitin-protein transferase activity" "0006511=ubiquitin-dependent protein catabolic process, 0045676=regulation of R7 cell differentiation, 0007465=R7 cell fate commitment, 0006508=proteolysis, 0007423=sensory organ development, 0010498=proteasomal protein catabolic process, 0016567=protein ubiquitination" "0000151=ubiquitin ligase complex, 0005634=nucleus, 0005737=cytoplasm" "Seven in absenti, unnamed, Sina, SINA, anon-fast-evolving-2H7, sia, SEVEN-IN-ABSENTIA, CG9949, seven-in-absentia, anon-EST:fe2H7" "IPR013323=SIAH-type domain, IPR004162=E3 ubiquitin-protein ligase SIN-like, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR018121=Seven-in-absentia protein, TRAF-like domain, IPR008974=TRAF-like, IPR013010=Zinc finger, SIAH-type" CG9949 16-Dec-15 2015_12 ENSDARG00000044381(siah2l) WBGene00021369(siah-1) "ENSXETG00000008090(siah1),ENSXETG00000020096(SIAH2)" "ENSMUSG00000040749(Siah1b),ENSMUSG00000036840(Siah1a),ENSMUSG00000036432(Siah2)" ENSG00000181788(SIAH2) embryonic stage -- adult stage " larval stage | third instar , pupal stage | 40 hr " " embryonic/larval hindgut

, morphogenetic furrow | anterior to

, retina

, embryonic/larval fat body

, cone cell

, photoreceptor cell R3 | presumptive

, photoreceptor cell R1 | presumptive

, peripodial epithelium &&of dorsal mesothoracic disc

, five-cell ommatidial precursor cluster

, embryonic/larval midgut

, peripodial epithelium

, photoreceptor cell R1--8

, peripodial epithelium &&of eye-antennal disc

, ommatidium

, photoreceptor cell R4 | presumptive

, photoreceptor cell R6 | presumptive

, pigment cell

, eye-antennal disc

, photoreceptor cell R7 | presumptive

, morphogenetic furrow | posterior to

, peripodial epithelium &&of ventral thoracic disc

" "viable,wild-type,visible,female sterile,male sterile,hypoactive,recessive,behavior defective,uncoordinated,short lived,sterile" "wing,eye,ommatidium,pigment cell,eye photoreceptor cell,cone cell,photoreceptor cell R7,macrochaeta,photoreceptor cell R1,somatic clone,supernumerary,mesothoracic tergum & microchaeta,adult abdominal segment 3 & microchaeta,adult abdominal segment 4 & microchaeta,mesothoracic tergum & trichogen cell | supernumerary,mesothoracic tergum & tormogen cell | supernumerary,mesothoracic tergum & chaeta,adult abdominal segment 3 & trichogen cell | supernumerary,adult abdominal segment 3 & tormogen cell | supernumerary,adult abdominal segment 3 & chaeta,adult abdominal segment 4 & trichogen cell | supernumerary,adult abdominal segment 4 & tormogen cell | supernumerary,adult abdominal segment 4 & chaeta,trichogen cell,external sensory organ,photoreceptor cell R8 of pale ommatidium,photoreceptor cell R6,microchaeta,medial triple row,dorsal double row,eo neuron,thecogen cell,presumptive embryonic/larval peripheral nervous system,wing margin bristle,chaeta,ectopic" FBgn0053830 His3:CG33830 His3:CG33830 http://flybase.net/reports/FBgn0053830.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33830 "IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A, IPR009072=Histone-fold" CG33830 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0003308 ry rosy http://flybase.net/reports/FBgn0003308.html protein_coding_gene "0043546=molybdopterin cofactor binding, 0004855=xanthine oxidase activity, 0008762=UDP-N-acetylmuramate dehydrogenase activity, 0005506=iron ion binding, 0050660=flavin adenine dinucleotide binding, 0051537=2 iron, 2 sulfur cluster binding, 0009055=electron carrier activity, 0004854=xanthine dehydrogenase activity" "0048072=compound eye pigmentation, 0006206=pyrimidine nucleobase metabolic process, 0045471=response to ethanol, 0006650=glycerophospholipid metabolic process, 0009115=xanthine catabolic process, 0008340=determination of adult lifespan, 0006144=purine nucleobase metabolic process, 0006525=arginine metabolic process, 0006568=tryptophan metabolic process, 0055114=oxidation-reduction process" "0005875=microtubule associated complex, 0005777=peroxisome" "xdh, Xdh, Xanthine dehydrogenase, CG7642, Rosy, Xdh/ry, unnamed, xanthine dehydrogenase, XDH, Xanthine DH, XOR" "IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR022407=Oxidoreductase, molybdopterin binding site, IPR008274=Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR005107=CO dehydrogenase flavoprotein, C-terminal, IPR014307=Xanthine dehydrogenase, small subunit, IPR016208=Aldehyde oxidase/xanthine dehydrogenase, IPR002346=Molybdopterin dehydrogenase, FAD-binding, IPR000674=Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041=2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR012675=Beta-grasp domain, IPR002888=[2Fe-2S]-binding, IPR006058=2Fe-2S ferredoxin, iron-sulphur binding site, IPR016166=FAD-binding, type 2, IPR016167=FAD-binding, type 2, subdomain 1" CG7642 16-Dec-15 2015_12 ENSDARG00000055240(xdh) WBGene00010083(F55B11.1) ENSXETG00000022078(XDH) ENSMUSG00000024066(Xdh) ENSG00000158125(XDH) secondary pigment cell pigment granule

"electrophoretic variant,partially lethal - majority die,partially,recessive,heat sensitive,eye color defective,wild-type,viable,chemical sensitive,radiation sensitive,fertile,short lived,male" "pigment cell,Malpighian tubule" FBgn0004956 upd1 unpaired 1 http://flybase.net/reports/FBgn0004956.html "FBgn0003012, FBgn0003956, FBgn0016985" protein_coding_gene "0005102=receptor binding, 0005125=cytokine activity, 0016015=morphogen activity" "0008039=synaptic target recognition, 0042078=germ-line stem cell division, 0007350=blastoderm segmentation, 0030707=ovarian follicle cell development, 0001700=embryonic development via the syncytial blastoderm, 0046427=positive regulation of JAK-STAT cascade, 0007259=JAK-STAT cascade, 0017145=stem cell division, 0045824=negative regulation of innate immune response, 0003383=apical constriction, 0036335=intestinal stem cell homeostasis, 0060729=intestinal epithelial structure maintenance, 0060031=mediolateral intercalation, 0007442=hindgut morphogenesis, 0050829=defense response to Gram-negative bacterium, 0007298=border follicle cell migration, 0048103=somatic stem cell division, 0016476=regulation of embryonic cell shape, 0007616=long-term memory, 0001745=compound eye morphogenesis, 0007455=eye-antennal disc morphogenesis, 0045475=locomotor rhythm, 0007538=primary sex determination, 0010536=positive regulation of activation of Janus kinase activity, 0007530=sex determination, 0007540=sex determination, establishment of X:A ratio, 0007440=foregut morphogenesis, 0038001=paracrine signaling, 0006952=defense response, 0044719=regulation of imaginal disc-derived wing size" "0005576=extracellular region, 0045177=apical part of cell, 0031012=extracellular matrix, 0005578=proteinaceous extracellular matrix, 0005615=extracellular space" "unpaired, outstretched small eye, l(1)YC43, upd, Unpaired/Out-stretched, CG5993, sisC, sy, sis-c, unpaired 1, upd homolog, Unpaired 1, Upd, os, Outstretched, upd1, sisterless c, unp, outstretched-smalleye, UPD, OS, small-eye, sis-C, od, Unpaired, Os, upa, Upd1, outstretched, l(1)YM55, odsy" CG5993 16-Dec-15 2015_12 " embryonic stage | stage 4,5 , embryonic stage | stage >8 , embryonic stage | stage 6,7 " "

pair rule , embryonic/larval tracheal pit

,

segment polarity " "visible,locomotor rhythm defective,RU486 conditional,hyperplasia,memory defective,recessive,lethal,planar polarity defective,somatic clone,cell shape defective,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell number,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,viable,reduced,female sterile,developmental rate defective,partially lethal - majority die,size defective,cell non-autonomous,mitotic cell cycle defective,increased cell growth,immune response defective,conditional" "eye,wing,wing disc,border follicle cell,somatic clone,gonad | ectopic & embryo,ommatidium,embryonic abdominal segment 4,embryonic abdominal segment 5,ectoderm,polar follicle cell,interfollicle cell,supernumerary,egg chamber,oocyte,eye-antennal disc,eye disc,embryonic/larval cuticle,mesothoracic segment,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,larval head,eye disc anterior to the morphogenetic furrow,tergite,denticle belt & abdominal segment 4,denticle belt & abdominal segment 5,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 8,adult abdominal segment,embryonic segment,plasmatocyte,embryonic/larval proventriculus,ectopic,cuticle & adult external headey.PH,morphogenetic furrow,testis,germline stem cell,male germline stem cell,primary gonial cell,cyst progenitor cell,spermatogonium,round stem cell fusome,cyst cell,stem cell fusome,germline cell | embryonic stage,eye disc | third instar larval stage,photoreceptor cell R8,cell non-autonomous,somatic clone | third instar larval stage,dorsal,ventral,centripetally migrating follicle cell,oocyte associated follicle cell,embryonic head,extended germ band embryo,amnioserosa,embryonic hindgut,pole cell,germarium,germline cyst,female germline stem cell,ovariole,escort stem cell,intestinal stem cell,male germline cell,somatic cell of testis,posterior,adult midgut epithelium" FBgn0010300 brat brain tumor http://flybase.net/reports/FBgn0010300.html "FBgn0002034, FBgn0004827, FBgn0027355" protein_coding_gene "0045182=translation regulator activity, 0008270=zinc ion binding, 0005515=protein binding, 0030371=translation repressor activity" "0048477=oogenesis, 0035282=segmentation, 0007405=neuroblast proliferation, 0007400=neuroblast fate determination, 0007406=negative regulation of neuroblast proliferation, 1900242=regulation of synaptic vesicle endocytosis, 0009303=rRNA transcription, 0006909=phagocytosis, 0007402=ganglion mother cell fate determination, 0030182=neuron differentiation, 0050767=regulation of neurogenesis, 0016072=rRNA metabolic process, 0008285=negative regulation of cell proliferation, 0006417=regulation of translation, 0055060=asymmetric neuroblast division resulting in ganglion mother cell formation, 0008582=regulation of synaptic growth at neuromuscular junction, 0007420=brain development, 0007411=axon guidance, 0022008=neurogenesis, 0008356=asymmetric cell division, 0051726=regulation of cell cycle" "0043025=neuronal cell body, 0005737=cytoplasm, 0045180=basal cortex, 0045179=apical cortex" "BRAT, Brain Tumor, fs(2)ltoPM43, l(2)brat, brain tumour, Brain tumor, anon-37CDa, l(2)E60, lincRNA.S1565, Brat, Cf, l(2)37Cf, CG10719, E60" "IPR001258=NHL repeat, IPR013017=NHL repeat, subgroup, IPR000315=B-box-type zinc finger, IPR011042=Six-bladed beta-propeller, TolB-like" CG10719 16-Dec-15 2015_12 WBGene00003559(ncl-1) " embryonic stage | stage >=11 , embryonic stage | stage >=12 , embryonic stage | stage 16 , embryonic stage | stage 13-16 " " embryonic ventral nervous system

, embryonic peripheral nervous system

, embryonic brain

, peripheral nervous system precursor cluster

, antenno-maxillary complex

, embryonic ganglion mother cell

" "neuroanatomy defective,somatic clone,viable,fertile,lethal,recessive,tumorigenic,decreased cell number,female sterile,wild-type,mitotic cell cycle defective,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect,neurophysiology defective,endocytosis defective,heat sensitive,partially lethal - majority die,increased cell size,increased cell number,visible,cell non-autonomous" "embryonic/larval brain,embryonic epidermis,embryonic abdominal segment,embryonic abdomen,type II neuroblast,supernumerary,female germline stem cell,egg chamber,female germline cyst,female germline cell,germarium,embryo,germline clone,maternal effect,posterior,neuroblast,somatic clone,axon | somatic clone,NMJ bouton,synaptic vesicle,presynaptic active zone membrane,postsynaptic density,wing & trichogen cell,adult thorax,nucleolus | somatic clone,cell autonomous,adult brain,ganglion mother cell,imaginal disc,RP2 motor neuron,neuron,mitotic cell cycle | somatic clone,eye,1st posterior cell,wing,anterior compartment,cell non-autonomous,embryonic/larval neuroblast,supernumerary | third instar larval stage" DRSC03497 IEK 0.919362124 -2.082503528 2.188936656 -2.667520671 0.900406851 1.6821938 FBgn0020309 crol crooked legs http://flybase.net/reports/FBgn0020309.html "FBgn0010573, FBgn0010685, FBgn0025949, FBgn0025978" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0030178=negative regulation of Wnt signaling pathway, 0045931=positive regulation of mitotic cell cycle, 0031935=regulation of chromatin silencing, 0045892=negative regulation of transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter, 0007476=imaginal disc-derived wing morphogenesis, 0046331=lateral inhibition, 0007155=cell adhesion" 0005634=nucleus "CG14938, Crooked legs, anon-EST:Liang-2.48, l(2)s2346, Crol, crol gamma, anon-EST:Liang-1.74, crooked-legs, clone 2.48, crol beta, crol alpha, l(2)04418, clone 1.74, ORE-15" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG14938 16-Dec-15 2015_12 "ENSDARG00000058562(zgc:123008),ENSDARG00000058566,ENSDARG00000035150(LOC555591)" "ENSXETG00000015069(TNeu022l11.1),ENSXETG00000011313(),ENSXETG00000016619(),ENSXETG00000017175(),ENSXETG00000023597(),ENSXETG00000002834(),ENSXETG00000024253(),ENSXETG00000023997(),ENSXETG00000024362(TGas096a15.1),ENSXETG00000023643(),ENSXETG00000011624(),ENSXETG00000002695(),ENSXETG00000025844(),ENSXETG00000013017(),ENSXETG00000011713(),ENSXETG00000002717(),ENSXETG00000023928(),ENSXETG00000006489(),ENSXETG00000027145(),ENSXETG00000024254(),ENSXETG00000013882(),ENSXETG00000027712(),ENSXETG00000008705(),ENSXETG00000010805(),ENSXETG00000019840(),ENSXETG00000002097(ZNF658B),ENSXETG00000024242(),ENSXETG00000017171(),ENSXETG00000027149(),ENSXETG00000024337(TGas123i16.1)" "ENSMUSG00000078502,ENSMUSG00000062518,ENSMUSG00000066009(Gm13051),ENSMUSG00000066007(Zfp600),ENSMUSG00000078495(Gm13157),ENSMUSG00000078503(Gm13225),ENSMUSG00000070605(Gm13251),ENSMUSG00000067916(Gm13139),ENSMUSG00000078499(Rex2),ENSMUSG00000067919,ENSMUSG00000059142,ENSMUSG00000058186,ENSMUSG00000065999(Gm13154),ENSMUSG00000002617(Zfp40),ENSMUSG00000074867(Zfp808),ENSMUSG00000023892(Zfp51),ENSMUSG00000058402(Zfp420),ENSMUSG00000044501(Zfp758),ENSMUSG00000078877,ENSMUSG00000062040(Zfp27),ENSMUSG00000056592(Zfp658),ENSMUSG00000067928(Zfp760),ENSMUSG00000021510(A530054K11Rik),ENSMUSG00000051341(Zfp52),ENSMUSG00000071266(1300003B13Rik),ENSMUSG00000067942(Zfp160),ENSMUSG00000072763(5430403G16Rik),ENSMUSG00000006720(Zfp184),ENSMUSG00000069743(Zfp820),ENSMUSG00000063108(Zfp26),ENSMUSG00000079008,ENSMUSG00000062743(Zfp677),ENSMUSG00000061544(Zfp229),ENSMUSG00000046311(Zfp62),ENSMUSG00000069204(Zfp748),ENSMUSG00000072762,ENSMUSG00000078902(Gm14443),ENSMUSG00000074165(Zfp788),ENSMUSG00000055480(Zfp458),ENSMUSG00000061371(Zfp873),ENSMUSG00000063047(Zfp780b),ENSMUSG00000051034(Zfp11),ENSMUSG00000078903(Gm14391),ENSMUSG00000068130(Zfp442),ENSMUSG00000063281(Zfp35),ENSMUSG00000078564,ENSMUSG00000059975(Zfp74),ENSMUSG00000068959(Zfp619),ENSMUSG00000057409(Zfp53),ENSMUSG00000012640(Zfp715),ENSMUSG00000078893(Gm2004),ENSMUSG00000078875,ENSMUSG00000056019(Zfp709),ENSMUSG00000062862(Zfp111),ENSMUSG00000066613,ENSMUSG00000070709(1700049G17Rik),ENSMUSG00000057396(Zfp759),ENSMUSG00000044676(Zfp612),ENSMUSG00000078887,ENSMUSG00000078862(Gm14326),ENSMUSG00000062861(Zfp28),ENSMUSG00000029587(Zfp12),ENSMUSG00000078868,ENSMUSG00000054737(Zfp182),ENSMUSG00000057842(Zfp595),ENSMUSG00000067931(BC049807),ENSMUSG00000047603(Zfp235),ENSMUSG00000055341(Zfp457)" "ENSG00000198040(ZNF84),ENSG00000196458(ZNF605),ENSG00000197619(ZNF615),ENSG00000196437(ZNF569),ENSG00000197800,ENSG00000196967(ZNF585A),ENSG00000196693(ZNF33B),ENSG00000096654(ZNF184),ENSG00000197937(ZNF347),ENSG00000170949(ZNF160),ENSG00000147124(ZNF41),ENSG00000197566(ZNF624),ENSG00000197050(ZNF420),ENSG00000189180(ZNF33A),ENSG00000127081(ZNF484),ENSG00000187187(ZNF546),ENSG00000197016(ZNF470),ENSG00000198566,ENSG00000196409(ZNF658),ENSG00000198416,ENSG00000164631(ZNF12),ENSG00000221897,ENSG00000204611(ZNF616),ENSG00000160321(ZNF208),ENSG00000213967(ZNF726),ENSG00000196267(ZNF836),ENSG00000128000(ZNF780B),ENSG00000146587(RBAK-LOC389458),ENSG00000197497(ZNF665),ENSG00000167232(ZNF91),ENSG00000130684(ZNF337),ENSG00000186448(ZNF197),ENSG00000196350(ZNF729),ENSG00000186272(ZNF17),ENSG00000160336,ENSG00000197608(ZNF841),ENSG00000198521(ZNF43),ENSG00000147118(ZNF182),ENSG00000131115(ZNF227),ENSG00000196268(ZNF493),ENSG00000198453(ZNF568),ENSG00000198182(ZNF607),ENSG00000196597(ZNF782),ENSG00000180626(ZNF594),ENSG00000198482(ZNF808),ENSG00000176293(ZNF135),ENSG00000204519(ZNF551),ENSG00000170631(ZNF16),ENSG00000189144(ZNF573),ENSG00000197013(ZNF429),ENSG00000196757(ZNF700),ENSG00000196724(ZNF418),ENSG00000159917(ZNF235),ENSG00000166704(ZNF606),ENSG00000196826(ZNF709),ENSG00000186019(ZNF224),ENSG00000189042(ZNF567),ENSG00000185947(ZNF267),ENSG00000221994(ZNF630),ENSG00000213861,ENSG00000189190(ZNF600),ENSG00000198538(ZNF28),ENSG00000197647(ZNF433),ENSG00000167555(ZNF528),ENSG00000167380(ZNF234),ENSG00000167377(ZNF23),ENSG00000145908(ZNF300),ENSG00000167383(ZNF229),ENSG00000159905(ZNF221),ENSG00000131849(ZNF132),ENSG00000168661(ZNF30),ENSG00000182903(ZNF721),ENSG00000171817(ZNF540),ENSG00000081665(ZNF506),ENSG00000196670(ZFP62),ENSG00000196263(ZNF471),ENSG00000124459(ZNF45),ENSG00000136870(ZNF189),ENSG00000147789(ZNF7),ENSG00000196247(ZNF107),ENSG00000197782(ZNF780A),ENSG00000125846(ZNF133),ENSG00000105708(ZNF14),ENSG00000159904,ENSG00000197701(ZNF595),ENSG00000131845(ZNF304),ENSG00000105497(ZNF175),ENSG00000198131(ZNF544),ENSG00000180479(ZNF571),ENSG00000196172(ZNF681),ENSG00000105750(ZNF85),ENSG00000205903,ENSG00000141040(ZNF287),ENSG00000197779(ZNF81),ENSG00000213096(ZNF254),ENSG00000198185(ZNF334),ENSG00000167637(ZNF283),ENSG00000136866(ZFP37),ENSG00000196867(ZFP28),ENSG00000198169(ZNF251),ENSG00000176232,ENSG00000213020(ZNF611),ENSG00000198028(ZNF560),ENSG00000176024(ZNF613),ENSG00000180855(ZNF443),ENSG00000196110(ZNF699),ENSG00000186230(ZNF749),ENSG00000164256(PRDM9),ENSG00000196109(ZNF676),ENSG00000152454(ZNF256),ENSG00000198393(ZNF26),ENSG00000184939(ZFP90)" " larval stage | third instar , prepupal stage " "viable,fertile,lethal,recessive,mitotic cell cycle defective,somatic clone,long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective,female limited,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,visible,increased cell death,cell death defective,partially lethal - majority die" "wing vein,ectopic,ventral thoracic disc,leg,wing,femur,wing pouch,somatic clone,macrochaeta,stage P5 pupa,pupa,adult head,stage P14 pharate adult,metathoracic leg,metathoracic femur,metathoracic leg sensillum,intersegmental nerve,posterior compartment,wing disc,morphogenetic furrow,chaeta,supernumerary,mesothoracic tergum" DRSC21348 K -0.963320905 -0.071652027 -0.315914999 1.041765843 -1.634031783 -1.546821786 FBgn0004378 Klp61F Kinesin-like protein at 61F http://flybase.net/reports/FBgn0004378.html "FBgn0004923, FBgn0010911, FBgn0015744" protein_coding_gene "0008574=ATP-dependent microtubule motor activity, plus-end-directed, 0005524=ATP binding, 0003777=microtubule motor activity, 0003774=motor activity, 0008017=microtubule binding" "0000278=mitotic cell cycle, 0007018=microtubule-based movement, 0022008=neurogenesis, 0007052=mitotic spindle organization, 0007067=mitotic nuclear division, 0007100=mitotic centrosome separation, 0043148=mitotic spindle stabilization, 0051289=protein homotetramerization, 0051299=centrosome separation, 0031535=plus-end directed microtubule sliding, 0009306=protein secretion, 0051298=centrosome duplication, 0007030=Golgi organization, 0001578=microtubule bundle formation" "0005819=spindle, 0005737=cytoplasm, 0005794=Golgi apparatus, 0005813=centrosome, 0005874=microtubule, 1990498=mitotic spindle microtubule, 0005873=plus-end kinesin complex, 0005871=kinesin complex, 0045169=fusome, 0005783=endoplasmic reticulum, 0005875=microtubule associated complex" "KRP[[(130)]], Krp130, Kin-5, kinesin-5s, kinesin-5 motor, Kinesin-related protein-130kD, Klp61F/KRP130, 6345, Klp2, CG9191-PA, urcn, KLP61f, urc, l(3)Klp61F, kinesin-like protein, KLP2, kinesin-5, l(3)6D283, urchin, l(3)07012, KIF11, KLP61, KIF 8, CG9191, klp61f, DmKRP130, DmKlp61F, KLP61F, Klp61f, KRP[[130]], DmKLP61F, KRP130, Klp 61F, klp61F" "IPR025901=Kinesin-associated microtubule-binding domain, IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9191 16-Dec-15 2015_12 ENSDARG00000010948(kif11) YBL063W(KIP1) WBGene00000257(bmk-1) ENSXETG00000012213(KIF11) ENSMUSG00000012443(Kif11) ENSG00000138160(KIF11) " embryonic stage && larval stage && pupal stage , adult stage | female , adult stage | male , embryonic stage , embryonic stage | stage 6 " " ovary

, testis

, ventral midline

, ventral nervous system | restricted

, mesoderm anlage

, cephalic furrow

" "viable,fertile,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cytokinesis defective,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,neuroanatomy defective" "spindle | embryonic stage,spindle | embryonic stage, with Klp61F07012,spermatocyte fusome,nuclear chromosome,embryonic/larval brain,imaginal disc,centriole & spermatocyte,aster & spermatocyte,spindle & spermatocyte,centrosome & spermatocyte,spermatocyte,spermatid,spindle,mitotic cell cycle & spermatocyte,meiotic telophase II & spermatocyte,nuclear lamina & spermatocyte,spindle & neuroblast & larva,nuclear lamina & neuroblast & larva,aster & neuroblast & larva,centrosome & neuroblast & larva,embryonic/larval neuroblast,spindle | pre-blastoderm stage,spindle microtubule | embryonic stage 4,aster & spermatocytebab-PG),spindle & spermatocytebab-PG),centrosome & spermatocytebab-PG),microtubule organizing center | pre-blastoderm stage,spindle | embryonic stage, with Klp61FUbi-p63E.TAvicGFP/Klp61F06836,testis,larval brain & nuclear chromosome & larva,somatic clone,spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,S2 cell-line,ganglion mother cell" DRSC08671 IE 1.72234719 -2.332438086 0.869235011 -3.139821157 0.143621329 1.224654645 FBgn0283472 S6k Ribosomal protein S6 kinase http://flybase.net/reports/FBgn0283472.html "FBgn0015806, FBgn0010455, FBgn0011551, FBgn0004460" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004711=ribosomal protein S6 kinase activity, 0005515=protein binding, 0005524=ATP binding" "0048477=oogenesis, 0007520=myoblast fusion, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 0007584=response to nutrient, 0006974=cellular response to DNA damage stimulus, 0008361=regulation of cell size, 0046622=positive regulation of organ growth, 0006909=phagocytosis, 0030536=larval feeding behavior, 0040018=positive regulation of multicellular organism growth, 0048813=dendrite morphogenesis, 2000331=regulation of terminal button organization, 0030307=positive regulation of cell growth, 0035264=multicellular organism growth, 0045927=positive regulation of growth, 0051124=synaptic growth at neuromuscular junction, 0006979=response to oxidative stress, 0016239=positive regulation of macroautophagy, 0040007=growth, 0045793=positive regulation of cell size, 0010508=positive regulation of autophagy, 0007411=axon guidance, 0007015=actin filament organization, 0007165=signal transduction, 2001023=regulation of response to drug, 0007525=somatic muscle development, 0006629=lipid metabolic process" "0005654=nucleoplasm, 0048786=presynaptic active zone, 0005829=cytosol" "p70 S6 Kinase, p70[S6 kinase], p70S6K kinase, p70/S6K, p70[S6k], p70S6 kinase, ribosomal S6 protein kinase, 10539, p70S6K, Pk64F, DS6K, l(3)07084, p70 S6 kinase, dp70[S6k], 7084, S6 kinase, p70 S6K, s6k, ds6k, dps6k, ribosomal protein S6 kinase, Dp70s6k, S6K1, Dp70[s6k], Pk?6, p70[S6kinase], 7-10, p-S6K, dS6K, p70s6K, S6-kinase, S6kinase, RPS6-p70-protein kinase, dS6k, fs(3)07084, p70 s6 kinase, S6k|S6K, S6K, Protein kinase-like 64F, s6k11, S6 Kinase, p70 S6 kinase 1, S6K kinase, dp70s6k, p70[S6K], p70 ribosomal S6 kinase, dS6 kinase, CG10539, Dp70S6k" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR017892=Protein kinase, C-terminal, IPR016238=Ribosomal protein S6 kinase, IPR017441=Protein kinase, ATP binding site, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG10539 16-Dec-15 2015_12 "ENSDARG00000058230(rps6kb1),ENSDARG00000018399(LOC562242)" "YKL126W(YPK1),YMR104C(YPK2),YHR205W(SCH9)" WBGene00012929(rsks-1) ENSXETG00000010731(rps6kb1) "ENSMUSG00000020516(Rps6kb1),ENSMUSG00000024830(Rps6kb2)" "ENSG00000108443(RPS6KB1),ENSG00000175634(RPS6KB2)" "viable,small body,visible,neurophysiology defective,partially lethal - majority die,recessive,female sterile,lethal,partially,decreased cell size,lethal - all die before end of larval stage,some die during larval stage,size defective,decreased cell number,wild-type,cell autonomous,somatic clone,neuroanatomy defective,feeding behavior defective,long lived,increased cell number,increased cell size,large body,increased cell growth,chemical resistant,short lived,memory defective,heat sensitive" "segment border muscle,A1-7 dorsal acute muscle 1,embryonic/larval somatic muscle,embryonic myoblast,wing,oocyte,adult,wing & cell | somatic clone,ommatidium,somatic clone,cell | adult stage,wing & cell,wing disc,mitotic cell cycle | somatic clone,eye,larval salivary gland & nucleus,dendrite | somatic clone,dendritic arborizing neuron,embryonic/larval fat body,NMJ bouton,wing blade,salivary gland,trichogen cell" DRSC11276 I -1.527743561 2.457851183 -0.911281262 -1.151322699 0.056746863 0.686103813 FBgn0053866 His3:CG33866 His3:CG33866 http://flybase.net/reports/FBgn0053866.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33866 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG33866 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0265726 NnaD Drosophila Nna1 ortholog http://flybase.net/reports/FBgn0265726.html "FBgn0052627, FBgn0052628, FBgn0030513" protein_coding_gene "0017076=purine nucleotide binding, 0004181=metallocarboxypeptidase activity, 0008270=zinc ion binding" "0003407=neural retina development, 0007005=mitochondrion organization, 0006508=proteolysis, 0002164=larval development" 0005739=mitochondrion "CG44533, CG11428, CG32628, CG32627" "IPR000834=Peptidase M14, carboxypeptidase A" CG44533 16-Dec-15 2015_12 WBGene00018995(F56H1.5) "ENSXETG00000019937(AGBL2),ENSXETG00000020238(AGBL3)" "ENSMUSG00000040812(Agbl2),ENSMUSG00000038836(Agbl3)" "ENSG00000165923(AGBL2),ENSG00000146856(AGBL3)" DRSC19404 K -0.17179376 0.465275645 -0.257684559 0.76096315 2.386751242 -0.25729871 FBgn0032162 CG4592 http://flybase.net/reports/FBgn0032162.html protein_coding_gene 0004165=dodecenoyl-CoA delta-isomerase activity 0008152=metabolic process 0005739=mitochondrion "IPR029045=ClpP/crotonase-like domain, IPR001753=Crotonase superfamily" CG4592 16-Dec-15 2015_12 ENSDARG00000018002 ENSXETG00000017302(dci) ENSMUSG00000024132(Dci) ENSG00000167969(ECI1) viable FBgn0003124 polo polo http://flybase.net/reports/FBgn0003124.html "FBgn0010758, FBgn0016019, FBgn0027987, FBgn0028177, FBgn0046400" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005515=protein binding, 0005524=ATP binding" "0051257=meiotic spindle midzone assembly, 0035050=embryonic heart tube development, 0030954=astral microtubule nucleation, 0007058=spindle assembly involved in female meiosis II, 0007112=male meiosis cytokinesis, 0006909=phagocytosis, 0008104=protein localization, 0007406=negative regulation of neuroblast proliferation, 0035044=sperm aster formation, 0000915=actomyosin contractile ring assembly, 0034613=cellular protein localization, 0051297=centrosome organization, 0006468=protein phosphorylation, 0007052=mitotic spindle organization, 0035046=pronuclear migration, 0007140=male meiosis, 0007067=mitotic nuclear division, 0048600=oocyte fate commitment, 0007143=female meiotic division, 0022008=neurogenesis, 0030726=male germline ring canal formation, 0000278=mitotic cell cycle, 0007147=female meiosis II, 0007344=pronuclear fusion" "0005737=cytoplasm, 1990023=mitotic spindle midzone, 0005874=microtubule, 0005813=centrosome, 0000940=condensed chromosome outer kinetochore, 0005828=kinetochore microtubule, 0000922=spindle pole, 0005819=spindle, 0000776=kinetochore, 0005635=nuclear envelope, 0030496=midbody, 0005814=centriole" "POLO/PLK1, l(3)S025604, 1324/08, anon-WO0172774.3, POLO, l(3)S132408, PLK1, Polo protein kinase, l(3)01673, Polo, CG12306, Polo kinase, l(3)77Aa, 0256/04" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000959=POLO box duplicated domain, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG12306 16-Dec-15 2015_12 ENSDARG00000058471(plk1) YMR001C(CDC5) "WBGene00004043(plk-2),WBGene00004042(plk-1),WBGene00004044(plk-3)" ENSXETG00000010344(plk1) ENSMUSG00000030867(Plk1) ENSG00000166851(PLK1) " larval stage && spermatogenesis , embryonic stage -- adult stage , larval stage , embryonic stage | stage 4 , embryonic stage | blastoderm " " testis

, ventral nerve cord

, imaginal disc

, organism | ubiquitous

, larval optic lobe

, larval brain

" embryonic stage "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,hyperplasia,neuroanatomy defective,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,viable,sterile,somatic clone,cytokinesis defective,some die during third instar larval stage,female sterile,wild-type,male,meiotic cell cycle defective,female,reduced,cell cycle defective,partially lethal - majority die,partially lethal,maternal effect,some die during embryonic stage,lethal - all die before end of embryonic stage,dominant,visible" "neuroblast & centrosome & larva,testis,primary spermatocyte cyst,onion stage spermatid,Nebenkern,meiotic cell cycle & spindle | male,mitotic cell cycle,mitosis & nuclear chromosome,nuclear chromosome,aster,embryonic/larval cardial cell,neuroblast & larval brain,neuroblast & larval brain | somatic clone,spindle & neuroblast,germarium region 2a,synaptonemal complex,germarium region 3,adult abdomen,tergite,embryonic/larval neuroblast,embryonic/larval brain,macrochaeta,abdomen,germline cyst,meiotic cell cycle | female,polar body nucleus,spermatocyte & spindle,spermatocyte & pericentriolar material,spermatocyte & midbody,spermatid,neuroblast & mitotic anaphase & larva,meiosis II | female,meiotic metaphase II & spindle | female,meiosis II & aster | female,meiosis II & spindle | female,male pronucleus,female pronucleus,meiotic telophase II & contractile ring | female,spindle,centrosome,adult cuticle,germarium region 2b,germarium,type II neuroblast,somatic clone,supernumerary,egg,centrosome | embryonic stage 4,centrosome | embryonic stage 4 | maternal effect,ganglion mother cell,mesothoracic tergum" DRSC22359 EK 1.182863402 0.84616027 -0.441853429 -2.231780857 2.168500088 1.684353783 FBgn0053809 His3:CG33809 His3:CG33809 http://flybase.net/reports/FBgn0053809.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33809 "IPR000164=Histone H3/CENP-A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33809 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053880 His2B:CG33880 His2B:CG33880 http://flybase.net/reports/FBgn0053880.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33880 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000558=Histone H2B" CG33880 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0041188 Atx2 Ataxin-2 http://flybase.net/reports/FBgn0041188.html "FBgn0010892, FBgn0025221, FBgn0038338, FBgn0044786, FBgn0062074, FBgn0063367" protein_coding_gene 0005515=protein binding "0022416=chaeta development, 0032092=positive regulation of protein binding, 0009994=oocyte differentiation, 1901216=positive regulation of neuron death, 0060965=negative regulation of gene silencing by miRNA, 0090328=regulation of olfactory learning, 0007616=long-term memory, 0006909=phagocytosis, 0097167=circadian regulation of translation, 0022008=neurogenesis, 0048749=compound eye development, 0007614=short-term memory, 0030833=regulation of actin filament polymerization, 0051823=regulation of synapse structural plasticity, 0046959=habituation, 0042051=compound eye photoreceptor development, 0045475=locomotor rhythm" 0005737=cytoplasm "atx-2, CG5166, GH27029, BEST:GH27029, Ataxin 2, CG5166a, ATAXIN-2, anon-fast-evolving-2E1, dAtaxin-2, anon-WO0118547.351, Sca2, Datx2, SCA2, atx2, Dataxin-2, ATX2, anon-EST:fe2E1, anon-WO0140519.1, dAtx2, Atxain-2, Atx-2, dSCA2, l(3)06490, ataxin-2" "IPR009818=Ataxin-2, C-terminal, IPR025852=Ataxin 2, SM domain, IPR009604=LsmAD domain" CG5166 16-Dec-15 2015_12 "ENSDARG00000011597(atxn2l),ENSDARG00000052897(si:dkey-165i4.1)" WBGene00000231(atx-2) "ENSXETG00000014990(ATXN2L),ENSXETG00000020912(ATXN2)" "ENSMUSG00000042605(Atxn2),ENSMUSG00000032637(Atxn2l)" "ENSG00000204842(ATXN2),ENSG00000168488(ATXN2L)" "viable,lethal,recessive,visible,somatic clone,female sterile,germline clone,lethal - all die before end of larval stage,some die during larval stage,increased cell death,uncoordinated,partially lethal - majority die,decreased cell number,conditional,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,circadian behavior defective,learning defective,heat sensitive,locomotor rhythm defective" "eye,somatic clone,ommatidium,nurse cell,germline clone,oocyte,nurse cell & nucleus | germ-line clone,nurse cell & actin filament | germ-line clone,retina,eye disc,border follicle cell,adult thorax & chaeta, with Atx2UAS.cSa, [-],adult thorax & chaeta, with Atx2X1, [-],head,photoreceptor,conditional,embryonic/larval neuroblast" DRSC23010 K -0.179759034 1.948302039 FBgn0000257 car carnation http://flybase.net/reports/FBgn0000257.html "FBgn0027357, FBgn0040160" protein_coding_gene "0019905=syntaxin binding, 0005515=protein binding, 0000149=SNARE binding" "0006727=ommochrome biosynthetic process, 0006904=vesicle docking involved in exocytosis, 0046907=intracellular transport, 0008057=eye pigment granule organization, 0008340=determination of adult lifespan, 0009267=cellular response to starvation, 0031396=regulation of protein ubiquitination, 0000046=autophagic vacuole fusion, 0007032=endosome organization, 0008333=endosome to lysosome transport, 0035542=regulation of SNARE complex assembly, 0008593=regulation of Notch signaling pathway, 0045746=negative regulation of Notch signaling pathway, 0007040=lysosome organization, 0007220=Notch receptor processing, 0016197=endosomal transport, 0006897=endocytosis, 0016192=vesicle-mediated transport, 0048072=compound eye pigmentation, 0006622=protein targeting to lysosome" "0005764=lysosome, 0030897=HOPS complex, 0005829=cytosol, 0033263=CORVET complex, 0016020=membrane" "CG12230, Vps33a, VPS33a, carn, Vacuolar protein sorting protein 33, Carnation, Vps33, Vps33p, l(1)G0447, Car, Dm-Vps33, Vps33A, Vps33/carnation" "IPR001619=Sec1-like protein, IPR027482=Sec1-like, domain 2" CG12230 16-Dec-15 2015_12 "ENSDARG00000067559,ENSDARG00000010902" YLR396C(VPS33) WBGene00016960(vps-33.2) ENSXETG00000015443(VPS33B) ENSMUSG00000029434(Vps33a) ENSG00000139719(VPS33A) "viable,fertile,partially lethal - majority die,recessive,visible,short lived,male,eye color defective,decreased cell death,wild-type,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage" "eye,late endosome,pigment cell,Malpighian tubule,embryonic/larval brain,endosome,ommatidium,rhabdomere,spermatogonial cyst,male germline cell,somatic clone,rhabdomere | cell autonomous | somatic clone,wing,mesothoracic tergum,embryonic/larval fat body,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0015247 Diap2 Death-associated inhibitor of apoptosis 2 http://flybase.net/reports/FBgn0015247.html protein_coding_gene "0005515=protein binding, 0031625=ubiquitin protein ligase binding, 0008270=zinc ion binding, 0043027=cysteine-type endopeptidase inhibitor activity involved in apoptotic process, 0061630=ubiquitin protein ligase activity, 0089720=caspase binding" "0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0070936=protein K48-linked ubiquitination, 0033160=positive regulation of protein import into nucleus, translocation, 0061057=peptidoglycan recognition protein signaling pathway, 0043154=negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, 0070534=protein K63-linked ubiquitination, 0050829=defense response to Gram-negative bacterium, 0043066=negative regulation of apoptotic process, 0016567=protein ubiquitination, 0007423=sensory organ development, 0043281=regulation of cysteine-type endopeptidase activity involved in apoptotic process" 0048471=perinuclear region of cytoplasm "dIAP, IAP2, Inhibitor of apoptosis 2, DIAP, IAP-like protein, Diha, Drosophila inhibitor of apoptosis 2, DIAP2, dILP, DIAP-2, D-IAP2, CG8293, D-iap2, Inhibitor of Apoptosis Protein 2, inhibitor of apoptosis 2, DIHA, Diap2, Iap2, IAP, Drosophila melanogaster inhibitor of apoptosis 2, dIAP2, DIAPII, Ilp, diap2, inhibitor of apoptosis protein 2, Diap" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR001370=BIR repeat" CG8293 16-Dec-15 2015_12 "ENSDARG00000044619(birc2),ENSDARG00000058082(birc7)" WBGene00000250(bir-2) ENSXETG00000022183(birc3) "ENSMUSG00000032000(Birc3),ENSMUSG00000057367(Birc2)" "ENSG00000110330(BIRC2),ENSG00000023445(BIRC3)" embryonic stage&&larval stage&&adult stage "lethal - all die before end of pupal stage,some die during pupal stage,immune response defective,visible,body color defective,partially lethal - majority die,viable,radiation sensitive,cell death defective,conditional,fertile,increased cell death,chemical sensitive" "macrochaeta,supernumerary,trichogen cell,mesothoracic tergum,wing disc,eye,pigment cell" FBgn0265434 zip zipper http://flybase.net/reports/FBgn0265434.html "FBgn0005634, FBgn0002742, FBgn0004415, FBgn0010524, FBgn0044594, FBgn0026658" protein_coding_gene "0005524=ATP binding, 0032027=myosin light chain binding, 0003774=motor activity, 0042623=ATPase activity, coupled" "0007298=border follicle cell migration, 0007443=Malpighian tubule morphogenesis, 0045200=establishment of neuroblast polarity, 0070986=left/right axis specification, 0042060=wound healing, 0016203=muscle attachment, 0035159=regulation of tube length, open tracheal system, 0031036=myosin II filament assembly, 0035277=spiracle morphogenesis, open tracheal system, 0035017=cuticle pattern formation, 0022008=neurogenesis, 0007391=dorsal closure, 0051726=regulation of cell cycle, 1901739=regulation of myoblast fusion, 0008258=head involution, 0007297=ovarian follicle cell migration, 0046663=dorsal closure, leading edge cell differentiation, 0006936=muscle contraction, 0071260=cellular response to mechanical stimulus, 0046664=dorsal closure, amnioserosa morphology change, 0000281=mitotic cytokinesis, 0030239=myofibril assembly, 0007496=anterior midgut development, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0032507=maintenance of protein location in cell, 0007395=dorsal closure, spreading of leading edge cells, 0035317=imaginal disc-derived wing hair organization, 0045214=sarcomere organization, 0051259=protein oligomerization, 0001736=establishment of planar polarity, 0007435=salivary gland morphogenesis" "0032154=cleavage furrow, 0016460=myosin II complex, 0005938=cell cortex, 0030018=Z disc, 0044291=cell-cell contact zone, 0016459=myosin complex, 0070938=contractile ring, 0031252=cell leading edge, 0016461=unconventional myosin complex, 0005856=cytoskeleton, 0045179=apical cortex, 0005829=cytosol" "cytoplasmic myosin heavy chain, Myosin Heavy Chain, non muscle myosin, Myosin II heavy chain, myosin, nonmuscle myosin heavy chain, Myosin II, myosin heavy chain, cytoplasmic myosin, zipper, MHC, cytoplasmic myosin II, non-muscle myosin heavy-chain, zpr, zip/MyoII, Myosin heavy chain-cytoplasmic, Dm nmII, nmMHC, Myo-II heavy chain, lethal (2) 17F1, nonmuscle myosin II, Myosin, unnamed, Myo-II HC, nmy-2, myosin-heavy-chain-cytoplasmic, Mhc-c, ZIP, myosin 2, Myosin heavy chain, cytoplasmic myosin-II, NMMII, Myo II, anon-WO0140519.37, Enhancer of broad, Dronm-MII, DROMHC, Zip, myosins II, myosin II, Mhc-c[1], DmnmII, non-muscle Myosin II, NMM, Myo, myo II, Myosin-II, myoII, nonmuscle myosin II heavy chain, nonmuscle Myosin II heavychain, Myosin-2, Myo-II, MyoII, Myo2, non-muscle myosin II heavy chain, l(2)17F1, nonmuscle myosin-II heavy chain, Zipper, CG15792, Nonmuscle myosin-II, myosin II heavy chain, non-muscle myosin, Myosin 2, non-muscle myosin II, l(2)02957, Zipper heavy chain, Myosin HC, E(br)" "IPR001609=Myosin head, motor domain, IPR002928=Myosin tail, IPR000048=IQ motif, EF-hand binding site, IPR004009=Myosin, N-terminal, SH3-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027401=Myosin-like IQ motif-containing domain" CG15792 16-Dec-15 2015_12 "ENSDARG00000063295,ENSDARG00000009782(myh11),ENSDARG00000011200(myh9l2),ENSDARG00000001014(myh9l1),ENSDARG00000006281(LOC566080)" YHR023W(MYO1) WBGene00003776(nmy-1) "ENSXETG00000016345(MYH10),ENSXETG00000000233(MYH9),ENSXETG00000019058(MYH14)" "ENSMUSG00000020900(Myh10),ENSMUSG00000022443(Myh9),ENSMUSG00000018830(Myh11),ENSMUSG00000030739(Myh14)" "ENSG00000133026(MYH10),ENSG00000100345(MYH9),ENSG00000133392(MYH11),ENSG00000105357(MYH14)" " embryonic stage , embryonic stage && adult stage , embryonic stage | stage 8 " " embryonic central nervous system

, mesoderm

" FBgn0020299 stumps stumps http://flybase.net/reports/FBgn0020299.html "FBgn0024898, FBgn0025779, FBgn0028088, FBgn0038245, FBgn0051317, FBgn0063634" protein_coding_gene "0007427=epithelial cell migration, open tracheal system, 0007509=mesoderm migration involved in gastrulation, 0007426=tracheal outgrowth, open tracheal system, 0007507=heart development, 0007369=gastrulation, 0021782=glial cell development, 0007498=mesoderm development, 0001763=morphogenesis of a branching structure, 0008543=fibroblast growth factor receptor signaling pathway, 0007424=open tracheal system development, 0048477=oogenesis, 0007428=primary branching, open tracheal system, 0008078=mesodermal cell migration" "0005622=intracellular, 0005737=cytoplasm" "sms, heartbroken, Heartbroken, CG31317, C, dof, Dof, stumps/dof, anon-estC, Downstream of FGFR/Heartbroken/Stumps, Hbr, anon-EST:CL47, P1740, Hbr/Dof, hbr, Downstream-of-FGFR, 0837/10, Downstream of FGF receptor, i21, downstream of FGF receptor, gene C, DOF, heartbroken/dof, Dof/stumps/heartbroken, i28, Downstream of FGF, CG3375, dof/hbr/sms, l(3)S083710, dof/hbr, downstream of FGFR, CG18485, dof1, Downstream of FGFR, Stumps, l(3)09904, downstream-of-FGF receptor" "IPR020683=Ankyrin repeat-containing domain, IPR017893=DBB domain" CG31317 16-Dec-15 2015_12 ENSXETG00000010643(PIK3AP1) " embryonic stage | stage 11 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage 9,10 , embryonic stage | stage >5 , embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | syncytial blastoderm , embryonic stage | stage 11-12 " " tracheal pit

, embryonic/larval heart

, embryonic/larval tracheal system

, tracheal primordium

, mesoderm

, visceral mesoderm

, mesoderm anlage

, posterior midgut proper primordium

, anterior midgut proper primordium

,

ventral , embryonic glial cell

" " embryonic stage | stage 11 , larval stage | third instar , embryonic stage | stage <11 " " tracheal pit

, mesoderm

dorsal & restricted , dorsal mesothoracic disc && adepithelial cell

, mesoderm

" "lethal,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,cell migration defective,somatic clone,viable" "embryonic/larval trachea,pericardial cell primordium,terminal tracheal cell,somatic clone,embryonic/larval tracheal system,presumptive embryonic salivary gland,tracheal system,embryonic/larval somatic muscle,dorsal,embryonic/larval pericardial cell,cardioblast,somatic mesoderm,visceral mesoderm,mesoderm,egg,presumptive embryonic/larval central nervous system,longitudinal connective,embryonic/larval dorsal vessel,midgut constriction 2,trachea,dorsal vessel primordium,embryonic pericardial cell,dorsal air sac primordium,embryonic/larval dorsal branch,glial cell,subretinal glial cell,somatic clone | third instar larval stage" DRSC15332 E 0.898952777 -1.395533715 0.51074249 -1.595115772 0.081020658 0.982072361 FBgn0004177 mts microtubule star http://flybase.net/reports/FBgn0004177.html "FBgn0010514, FBgn0010703, FBgn0031953" protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0019208=phosphatase regulator activity" "0006909=phagocytosis, 0060070=canonical Wnt signaling pathway, 0007099=centriole replication, 0007051=spindle organization, 0007059=chromosome segregation, 0008360=regulation of cell shape, 0051298=centrosome duplication, 0051297=centrosome organization, 0048477=oogenesis, 0007155=cell adhesion, 0007098=centrosome cycle, 0007465=R7 cell fate commitment, 0045880=positive regulation of smoothened signaling pathway, 0090162=establishment of epithelial cell polarity, 0006470=protein dephosphorylation, 0000226=microtubule cytoskeleton organization, 0007015=actin filament organization, 0007406=negative regulation of neuroblast proliferation, 0000278=mitotic cell cycle, 0009416=response to light stimulus, 0007067=mitotic nuclear division, 0006914=autophagy, 0055059=asymmetric neuroblast division, 0051225=spindle assembly" "0000159=protein phosphatase type 2A complex, 0005737=cytoplasm, 0005654=nucleoplasm, 0005814=centriole" "MTS/PP2A, Microtubule-star, catalytic subunit C of type 2A protein phosphatase, PP2A-C, Protein phosphatase 2A at 28D, PP2A C, PP2a 28D, l(2)s5286, PP2A[[C]], PP2Ac, dPP2A, l(2)02496, 5559, PP2A[C], DmPp2A-28D, dPP2A-C, PP2A catalytic subunit, PP2a, protein phosphatase 2A, PP2A 28D, Microtubule star, Pp2A-28D, ER2-6, phosphatase 2A catalytic subunit, PP2, PP2A/MTS, CG7109, Pp2A, Mts, PP2A" "IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like" CG7109 16-Dec-15 2015_12 "ENSDARG00000053020(ppp2cb),ENSDARG00000053404(LOC100331674),ENSDARG00000030224(ppp2ca)" "YDL188C(PPH22),YDL134C(PPH21)" WBGene00002363(let-92) "ENSXETG00000016092(ppp2ca),ENSXETG00000018309(TEgg040c14.1-001)" "ENSMUSG00000009630(Ppp2cb),ENSMUSG00000020349(Ppp2ca)" "ENSG00000104695(PPP2CB),ENSG00000113575(PPP2CA)" " embryonic stage | early , embryonic stage | late , larval stage | third instar , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage && larval stage , embryonic stage , adult stage , embryonic stage | stage 9-11 , embryonic stage && larval stage && adult stage " " gonad

, embryonic/larval salivary gland

, imaginal disc

, supraesophageal ganglion

, nurse cell

,

ubiquitous , larval brain

, adult brain

, oocyte

, adult midgut

, neuroblast

, ventral nerve cord

" "visible,viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,neuroanatomy defective,planar polarity defective,locomotor rhythm defective,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone" "eye,embryonic/larval hemocyte | third instar larval stage,neuroblast,supernumerary,embryonic/larval brain,wing hair,microtubule & neuromuscular junction | larval stageelav.PLu,bouton & neuromuscular junction | larval stageelav.PLu,embryonic/larval neuroblast,wing margin,type II neuroblast,somatic clone" DRSC03574 IE 0.918009972 -3.40249302 0.404905368 -3.907711575 1.051818802 -0.556150787 FBgn0015777 nrv2 nervana 2 http://flybase.net/reports/FBgn0015777.html "FBgn0014867, FBgn0021885, FBgn0022206, FBgn0045319, FBgn0065838" protein_coding_gene "0005391=sodium:potassium-exchanging ATPase activity, 0008324=cation transmembrane transporter activity" "0061343=cell adhesion involved in heart morphogenesis, 0007605=sensory perception of sound, 0019991=septate junction assembly, 0007424=open tracheal system development, 0006812=cation transport, 0035151=regulation of tube size, open tracheal system, 0060857=establishment of glial blood-brain barrier, 0006813=potassium ion transport, 0035159=regulation of tube length, open tracheal system, 0035158=regulation of tube diameter, open tracheal system, 0006814=sodium ion transport" "0005886=plasma membrane, 0030424=axon, 0005918=septate junction, 0005890=sodium:potassium-exchanging ATPase complex" "Nirvana, NEST:bs13c10, Na[+]/K[+]ATPase, nirvana2, NaK ATPase, ecta, l(2)k04223, Nrv2, unnamed, nervana, Nrv, CG9261, 42kDa, Na,K-ATPase, nervana2, nrv2.2, Na[+]/K[+] ATPase, Nervana2, Na[+]/K[+]-ATPase, Nervana, ectatic, l(2)SH0329, Nervana 2, Nrv2.2, Na+/K+ ATPase, l(2)SH2 0329, l(2)k13315" IPR000402=Sodium/potassium-transporting ATPase subunit beta CG9261 16-Dec-15 2015_12 "ENSDARG00000013144(atp1b1a),ENSDARG00000015790(atp1b3a),ENSDARG00000037678(LOC100329243),ENSDARG00000042837(atp1b3b),ENSDARG00000013605(atp1b2a),ENSDARG00000034424(atp1b2b),ENSDARG00000053262(atp1b4)" "WBGene00010117(nkb-3),WBGene00007646(nkb-1)" "ENSXETG00000002414(atp1b1),ENSXETG00000004477(ATP1B4),ENSXETG00000025056(atp1b2)" "ENSMUSG00000026576(Atp1b1),ENSMUSG00000041329(Atp1b2),ENSMUSG00000016327(Atp1b4)" "ENSG00000143153(ATP1B1),ENSG00000129244(ATP1B2),ENSG00000101892(ATP1B4),ENSG00000069849(ATP1B3)" adult stage "

, adult abdomen

, abdomen

, adult head

" " embryonic stage , adult stage , embryonic stage -- adult stage " " embryonic peripheral nervous system

, adult abdomen

, leg

, head

, longitudinal connective

, commissure

, central nervous system

, adult head

, adult brain

, embryonic/larval garland cell

, adult thorax

, embryonic/larval posterior spiracle

, thoracico-abdominal ganglion

, optic lobe

" "lethal,recessive,neuroanatomy defective,viable,visible,auditory perception defective" "septate junction,embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,embryonic ganglionic branch & embryonic tracheole,septate junction & embryonic tracheal system,ganglionic branch primordium,dorsal trunk primordium,presumptive embryonic salivary gland,embryonic somatic muscle,tracheal branch primordium,trichogen cell,Johnston organ" FBgn0000769 fs(1)A1059 female sterile (1) A1059 http://flybase.net/reports/FBgn0000769.html gene 0048477=oogenesis "fs(1)K575[ts], fs(1)K575, fs(1)M60, fs(1)1059" 16-Dec-15 2015_12 "female sterile,heat sensitive" FBgn0053814 His2A:CG33814 His2A:CG33814 http://flybase.net/reports/FBgn0053814.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33814 "IPR002119=Histone H2A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33814 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0085259 CG34230 http://flybase.net/reports/FBgn0085259.html protein_coding_gene CG34230 16-Dec-15 2015_12 FBgn0065916 l(2)SH0168 lethal (2) SH0168 http://flybase.net/reports/FBgn0065916.html gene l(2)SH2 0168 16-Dec-15 2015_12 "lethal,recessive" FBgn0039882 CG11576 http://flybase.net/reports/FBgn0039882.html protein_coding_gene 0005829=cytosol IPR009357=Endogenous retrovirus receptor CG11576 16-Dec-15 2015_12 "ENSDARG00000042737(zgc:136909),ENSDARG00000018980(zgc:91890),ENSDARG00000062502(LOC100330887),ENSDARG00000031689(zgc:63774)" "WBGene00044637(Y47D7A.16),WBGene00021626(Y47D7A.14)" "ENSXETG00000006746(C20orf54),ENSXETG00000013476(Q66KK1_XENTR)" "ENSMUSG00000027463(2310046K01Rik),ENSMUSG00000022560(Gpr172b)" ENSG00000101276(C20orf54) "viable,fertile,lethal,partially lethal - majority die,some die during pupal stage" FBgn0067067 Nrt::Wnt2 Nrt::Wnt2 http://flybase.net/reports/FBgn0067067.html engineered_fusion_gene 16-Dec-15 2015_12 FBgn0003314 sam sperm amotile http://flybase.net/reports/FBgn0003314.html gene 16-Dec-15 2015_12 male sterile FBgn0060448 l(3)S121612 lethal (3) S121612 http://flybase.net/reports/FBgn0060448.html gene 1216/12 16-Dec-15 2015_12 "lethal,recessive" FBgn0053905 His4:CG33905 His4:CG33905 http://flybase.net/reports/FBgn0053905.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0005634=nucleus, 0000786=nucleosome" CG33905 "IPR019809=Histone H4, conserved site, IPR001951=Histone H4, IPR009072=Histone-fold" CG33905 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0264075 tgo tango http://flybase.net/reports/FBgn0264075.html "FBgn0015014, FBgn0003147, FBgn0011605" protein_coding_gene "0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0017022=myosin binding, 0003700=sequence-specific DNA binding transcription factor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity" "0048477=oogenesis, 0007424=open tracheal system development, 0007425=epithelial cell fate determination, open tracheal system, 0007517=muscle organ development, 0071456=cellular response to hypoxia, 0006357=regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0008347=glial cell migration, 0048666=neuron development, 0007422=peripheral nervous system development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007417=central nervous system development, 0048813=dendrite morphogenesis, 0032869=cellular response to insulin stimulus, 0045676=regulation of R7 cell differentiation, 0060173=limb development, 0007420=brain development, 0000122=negative regulation of transcription from RNA polymerase II promoter" "0005667=transcription factor complex, 0043234=protein complex, 0005634=nucleus, 0005737=cytoplasm" "jay, dTgo, PRD gene 7, prd7, paired-like 7, Tgo, Hif1, arnt, CG11987, TGO, HIF1b, DARNT, bHLHe4, ARNT, HIF-1beta, jaywalker, darnt, HIF-1, dARNT, dHIF-1beta, Tango, Arnt" "IPR001067=Nuclear translocator, IPR001610=PAC motif, IPR013767=PAS fold, IPR000014=PAS domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG11987 16-Dec-15 2015_12 "ENSDARG00000058449(arnt2),ENSDARG00000021855(arnt)" WBGene00000095(aha-1) "ENSXETG00000008942(ARNT),ENSXETG00000012988(ARNT2)" "ENSMUSG00000015522(Arnt),ENSMUSG00000015709(Arnt2)" "ENSG00000143437(ARNT),ENSG00000172379(ARNT2)" " embryonic stage | stage 15 , embryonic stage | stage 14 , embryonic stage | <8-12 hr , embryonic stage , oogenesis stage " " embryonic peripheral nervous system

, embryonic maxillary segment

, embryonic antennal segment

, embryonic gnathal segment

, embryonic mandibular segment

, embryonic labial segment

, leg | anlagen

,

ubiquitous " " embryonic stage | stage 15 , embryonic stage | stage 14 , embryonic stage | stage 11-17 , embryonic stage , embryonic stage | stage 11 " " embryonic peripheral nervous system

, embryonic/larval tracheal system

, embryonic maxillary segment

, embryonic mandibular segment

,

ubiquitous , embryonic antennal segment

, dorsal vessel primordium

, supraesophageal ganglion

, embryonic labial segment

, tracheal pit | surrounding

, ventral nerve cord

, embryonic/larval posterior spiracle

" FBgn0086676 spin spinster http://flybase.net/reports/FBgn0086676.html "FBgn0004571, FBgn0014134, FBgn0028602, FBgn0010657, FBgn0015991, FBgn0021981, FBgn0034078, FBgn0061174" protein_coding_gene "0008582=regulation of synaptic growth at neuromuscular junction, 0012501=programmed cell death, 0045477=regulation of nurse cell apoptotic process, 0006897=endocytosis, 0007422=peripheral nervous system development, 0045924=regulation of female receptivity, 0008347=glial cell migration, 0055085=transmembrane transport, 0010001=glial cell differentiation, 0040011=locomotion, 0043067=regulation of programmed cell death, 0090099=negative regulation of decapentaplegic signaling pathway, 0008333=endosome to lysosome transport, 0035193=larval central nervous system remodeling, 0007040=lysosome organization, 0048488=synaptic vesicle endocytosis, 0045476=nurse cell apoptotic process, 0009267=cellular response to starvation, 0048477=oogenesis, 0007619=courtship behavior" "0005886=plasma membrane, 0016021=integral component of membrane, 0031982=vesicle" "lethal (2) W5, l(2)k02511, benchwarmer, spinster, l(2R)W5, diphthong, Spin, bnch, Spinster/Benchwarmer, 25/11, l(2)k09905, CG8428, l(2)10403, Spinster, l(2)W5" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG8428 16-Dec-15 2015_12 "ENSDARG00000011925(spns1),ENSDARG00000035459(spns3),ENSDARG00000061017(spns2)" "WBGene00007549(C13C4.5),WBGene00008033(C39E9.10),WBGene00008598(F09A5.1),WBGene00013739(Y111B2A.19)" ENSXETG00000008338(SPNS1) "ENSMUSG00000030741(Spns1),ENSMUSG00000040447,ENSMUSG00000020798(Spns3)" "ENSG00000169682(SPNS1),ENSG00000183018(SPNS2),ENSG00000182557(SPNS3)" FBgn0028979 tio tiptop http://flybase.net/reports/FBgn0028979.html "FBan0012630, FBgn0032970" protein_coding_gene "0008270=zinc ion binding, 0046872=metal ion binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048730=epidermis morphogenesis, 0007380=specification of segmental identity, head, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0061330=Malpighian tubule stellate cell differentiation, 0048749=compound eye development, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "tiptop, Tiptop, Tio, CG12630" "IPR015880=Zinc finger, C2H2-like, IPR027008=Teashirt family, IPR007087=Zinc finger, C2H2, IPR026807=Protein tiptop/teashirt" CG12630 16-Dec-15 2015_12 "ENSDARG00000015959,ENSDARG00000005026(tshz1)" "ENSXETG00000017555(TSHZ2),ENSXETG00000016288(TSHZ3)" "ENSMUSG00000047907,ENSMUSG00000046982(Tshz1),ENSMUSG00000021217(Tshz3)" "ENSG00000121297(TSHZ3),ENSG00000179981(TSHZ1),ENSG00000182463(TSHZ2)" "viable,fertile,visible,homeotic" "antennal disc,eye,ectopic,somatic clone,larval labial segment,T1 beard,denticle,heat sensitive,eye photoreceptor cell,ectopic | third instar larval stage" FBgn0040308 Jafrac2 Thioredoxin peroxidase 2 http://flybase.net/reports/FBgn0040308.html FBgn0035389 protein_coding_gene "0005515=protein binding, 0004601=peroxidase activity, 0008379=thioredoxin peroxidase activity, 0016209=antioxidant activity" "0006979=response to oxidative stress, 0070417=cellular response to cold, 0042742=defense response to bacterium, 0055114=oxidation-reduction process, 0046427=positive regulation of JAK-STAT cascade, 0042744=hydrogen peroxide catabolic process, 0097190=apoptotic signaling pathway, 0006974=cellular response to DNA damage stimulus, 2001269=positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" "0005783=endoplasmic reticulum, 0005615=extracellular space, 0005829=cytosol, 0005576=extracellular region, 0012505=endomembrane system" "jafrac2, Peroxiredoxin 4156, Jafrac-2, Prx4, Jafrac, DPx4156, JafRac2, thioredoxin peroxidase, dPrx4, DPx-4156, peroxiredoxin 4, thioredoxin peroxidase 2 isoform A, thioredoxin peroxidase 2, 1274, CG1274, Prx4156" "IPR012336=Thioredoxin-like fold, IPR000866=Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR019479=Peroxiredoxin, C-terminal" CG1274 16-Dec-15 2015_12 ENSDARG00000069013(LOC100332012) "YML028W(TSA1),YDR453C(TSA2)" WBGene00006434(prdx-2) ENSXETG00000010361(prdx4) ENSMUSG00000025289(Prdx4) ENSG00000123131(PRDX4) "short lived,lethal,heat sensitive,increased cell death,viable,fertile,oxidative stress response defective,recessive,chemical sensitive" eye FBgn0033476 oys oysgedart http://flybase.net/reports/FBgn0033476.html protein_coding_gene 0071617=lysophospholipid acyltransferase activity "0008354=germ cell migration, 0007009=plasma membrane organization, 0030258=lipid modification, 0007291=sperm individualization" 0016020=membrane "Oysgedart, Oys, CG18445, O-acyl transferase" "IPR004299=Membrane bound O-acyl transferase, MBOAT" CG18445 16-Dec-15 2015_12 "ENSDARG00000042551(zgc:136552),ENSDARG00000031845(mboat2a),ENSDARG00000029356(zgc:101798)" YOR175C(ALE1) "WBGene00016934(mboa-3),WBGene00007446(mboa-4)" "ENSXETG00000000020(LPCAT3),ENSXETG00000008268(MBOAT2)" "ENSMUSG00000020646(Mboat2),ENSMUSG00000038732(Mboat1)" "ENSG00000143797(MBOAT2),ENSG00000172197(MBOAT1)" "viable,fertile,neuroanatomy defective" "intersegmental nerve,anterior fascicle & synapse | supernumerary,synapse" DRSC05203 IE -0.827486377 -1.818943882 -2.509067786 -0.947443599 0.386414695 -0.03786959 FBgn0025381 rush rush hour http://flybase.net/reports/FBgn0025381.html protein_coding_gene "0035091=phosphatidylinositol binding, 0046872=metal ion binding" "0048812=neuron projection morphogenesis, 0008333=endosome to lysosome transport, 0007032=endosome organization, 0006897=endocytosis" "0005770=late endosome, 0005769=early endosome" "Rush hour, EG:80H7.5, CG14782" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001849=Pleckstrin homology domain, IPR000306=FYVE zinc finger" CG14782 16-Dec-15 2015_12 ENSDARG00000021141(plekhf2) YDR313C(PIB1) WBGene00014019(ZK632.12) ENSXETG00000006669(PLEKHF2) ENSMUSG00000049969(Plekhf2) ENSG00000175895(PLEKHF2) "sleep defective,viable,fertile" late endosome FBgn0262954 Rpb12 Rpb12 http://flybase.net/reports/FBgn0262954.html "FBgn0085215, FBgn0043066" protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0006366=transcription from RNA polymerase II promoter, 0006351=transcription, DNA-templated" "0005665=DNA-directed RNA polymerase II, core complex" "CG34186, RPB12" "IPR006591=RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4, IPR029040=RNA polymerase subunit RPABC4/transcription elongation factor Spt4" CG34186 16-Dec-15 2015_12 YHR143W-A(RPC10) WBGene00009078(rpb-12) ENSXETG00000025929(polr2k) ENSG00000147669(POLR2K) FBgn0032821 CdGAPr Cd GTPase activating protein-related http://flybase.net/reports/FBgn0032821.html protein_coding_gene 0005096=GTPase activator activity "0007165=signal transduction, 0007266=Rho protein signal transduction, 0031290=retinal ganglion cell axon guidance" "d-CdGAPr, FBgn 32821, CdGAPr, GAP, CG10538, 10538, cdGAPr" "IPR008936=Rho GTPase activation protein, IPR001452=SH3 domain, IPR000198=Rho GTPase-activating protein domain" CG10538 16-Dec-15 2015_12 ENSXETG00000017543(ARHGAP33) ENSMUSG00000041444(Arhgap32) "ENSG00000138640(FAM13A),ENSG00000031003(FAM13B)" "viable,fertile,neuroanatomy defective" embryonic/larval optic stalk DRSC03289 K 0.323874705 1.013299345 0.305306149 0.965144837 2.472255767 0.660543908 FBgn0041171 ago archipelago http://flybase.net/reports/FBgn0041171.html "FBgn0035516, FBgn0062079" protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0030332=cyclin binding" "0031146=SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, 0071456=cellular response to hypoxia, 0007088=regulation of mitotic nuclear division, 0042023=DNA endoreduplication, 0045926=negative regulation of growth, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation, 1903146=regulation of mitochondrion degradation, 0060438=trachea development, 0060253=negative regulation of glial cell proliferation, 0035147=branch fusion, open tracheal system, 0030162=regulation of proteolysis, 0007096=regulation of exit from mitosis, 1900038=negative regulation of cellular response to hypoxia, 0007411=axon guidance" 0019005=SCF ubiquitin ligase complex "FBXW3, SCF[Ago], cdc4, anon-WO0118547.345, Archipelago, FBXW7, CG15010, DmFbw7, Ago" "IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR019775=WD40 repeat, conserved site, IPR001810=F-box domain" CG15010 16-Dec-15 2015_12 YFL009W(CDC4) ENSMUSG00000028086(Fbxw7) ENSG00000109670(FBXW7) "neuroanatomy defective,somatic clone,lethal,some die during second instar larval stage,some die during third instar larval stage,oxidative stress response defective,visible,increased cell size,recessive,increased cell number,lethal - all die before end of first instar larval stage,some die during first instar larval stage,mitotic cell cycle defective,small body,decreased cell size" "lateral H branch,lateral G branch,tracheole,supernumerary,embryonic/larval ganglionic branch,wing,posterior,wing vein,nurse cell,germline clone,nurse cell & nucleus | germ-line clone,wing disc,somatic clone,eye,RP2 motor neuron,ectopic,embryonic/larval tracheal system,embryonic/larval dorsal trunk,tracheal lumen,embryonic/larval lateral trunk,embryonic/larval dorsal branch,tracheal primordium,tracheal fusion cell,secondary pigment cell,tertiary pigment cell,interommatidial bristle,mitotic cell cycle | somatic clone,embryonic/larval trachea,conditional,follicle cell & nucleus | somatic clone,posterior compartment,heat sensitive,lateral F branch,cell non-autonomous" DRSC08463 I 0.713483512 4.150537993 1.466765347 1.472022389 0.126602644 -0.528701757 FBgn0010391 Gtp-bp GTP-binding protein http://flybase.net/reports/FBgn0010391.html "FBgn0025711, FBgn0030267" protein_coding_gene "0003924=GTPase activity, 0003729=mRNA binding, 0005047=signal recognition particle binding, 0005525=GTP binding" "0007409=axonogenesis, 0006614=SRP-dependent cotranslational protein targeting to membrane, 0050708=regulation of protein secretion" "0005785=signal recognition particle receptor complex, 0012505=endomembrane system, 0005789=endoplasmic reticulum membrane, 0005811=lipid particle" "SrpRalpha, CK00309, GTP-bp, GTP binding protein, BEST:CK00309, mAb 13D5, CG2522" "IPR013822=Signal recognition particle, SRP54 subunit, helical bundle, IPR007222=Signal recognition particle receptor, alpha subunit, N-terminal, IPR011012=Longin-like domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000897=Signal recognition particle, SRP54 subunit, GTPase domain, IPR003593=AAA+ ATPase domain" CG2522 16-Dec-15 2015_12 ENSDARG00000061124(srpr) YDR292C(SRP101) WBGene00009521(F38A1.8) ENSXETG00000003920() ENSMUSG00000032042(Srpr) ENSG00000182934(SRPR) lethal DRSC20251 I -0.848398353 1.641460526 0.21777279 0.413860062 0.66287942 0.506695935 FBgn0262579 Ect4 Ectoderm-expressed 4 http://flybase.net/reports/FBgn0262579.html "FBgn0035832, FBgn0085402, FBgn0062127, FBgn0035834, FBgn0035835, FBgn0040834" protein_coding_gene "1901214=regulation of neuron death, 0007165=signal transduction, 0048678=response to axon injury" "0043005=neuron projection, 0043025=neuronal cell body" "Ect4, CG7905, CG34373, CG13680, anon-WO0118547.272, CG43119, CG13681, dsarm, ect4, Drosophila sterile alpha and Armadillo motif, CG7915, Ect4/SARM" "IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR001660=Sterile alpha motif domain, IPR016024=Armadillo-type fold, IPR013761=Sterile alpha motif/pointed domain, IPR011989=Armadillo-like helical" CG43119 16-Dec-15 2015_12 ENSDARG00000010610(sarm1) embryonic stage | cellular blastoderm dorsal ectoderm anlage | restricted

DRSC10039 EK FBgn0001906 l(2)24Dd lethal (2) 24Dd http://flybase.net/reports/FBgn0001906.html gene "jf2, l(2)jf2" 16-Dec-15 2015_12 lethal FBgn0265217 fs(2)Z2-5646 http://flybase.net/reports/FBgn0265217.html gene 16-Dec-15 2015_12 female sterile FBgn0262456 mir-125 mir-125 stem loop http://flybase.net/reports/FBgn0262456.html "FBgn0043885, FBgn0064159, FBgn0053314, FBgn0262322" miRNA_gene "0071390=cellular response to ecdysone, 0010629=negative regulation of gene expression" "MiR-125b, mir-125b, dme-miR-125, dme-mir-125, mir-125, CR43029, 125, CR33314, miR-125" CR43029 16-Dec-15 2015_12 " prepupal stage--adult stage , prepupal stage--pupal stage | stage P5 " organism

FBgn0032420 CG6583 http://flybase.net/reports/FBgn0032420.html protein_coding_gene 0005829=cytosol CG6583 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0040638 CG12979 http://flybase.net/reports/FBgn0040638.html protein_coding_gene 16-Dec-15 2015_12 FBgn0083057 snoRNA:ë¬18S-110 snoRNA:ë¬18S-110 http://flybase.net/reports/FBgn0083057.html snoRNA_gene "psi18s-110, Psi 18S-110, CR34631, chr3L:815446..815549" CR34631 16-Dec-15 2015_12 FBgn0026241 gar gargantua http://flybase.net/reports/FBgn0026241.html gene 0045792=negative regulation of cell size 16-Dec-15 2015_12 FBgn0038886 CG6475 http://flybase.net/reports/FBgn0038886.html protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG6475 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" "viable,fertile,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0264089 sli slit http://flybase.net/reports/FBgn0264089.html "FBgn0003425, FBgn0022290, FBgn0053464" protein_coding_gene "0005515=protein binding, 0008201=heparin binding, 0005509=calcium ion binding, 0048495=Roundabout binding" "0007427=epithelial cell migration, open tracheal system, 0007411=axon guidance, 0046331=lateral inhibition, 0022409=positive regulation of cell-cell adhesion, 0007509=mesoderm migration involved in gastrulation, 0048813=dendrite morphogenesis, 0008406=gonad development, 0035050=embryonic heart tube development, 0007432=salivary gland boundary specification, 2000274=regulation of epithelial cell migration, open tracheal system, 0035385=Roundabout signaling pathway, 0008347=glial cell migration, 0003151=outflow tract morphogenesis, 0007502=digestive tract mesoderm development, 0010632=regulation of epithelial cell migration, 0030182=neuron differentiation, 0001764=neuron migration, 0050919=negative chemotaxis, 0016199=axon midline choice point recognition, 0008078=mesodermal cell migration" "0031012=extracellular matrix, 0005578=proteinaceous extracellular matrix, 0071666=Slit-Robo signaling complex" "lethal (2) 05248, slit, CT21700, wdh, Slit, SGP cluster fusion defects 3, CT37068, CG43758, Sli, dSlit, CG33464, CG8355, l(2)05248, fus3" "IPR006207=Cystine knot, C-terminal, IPR003591=Leucine-rich repeat, typical subtype, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR003590=Leucine-rich repeat, ribonuclease inhibitor subtype, IPR000483=Cysteine-rich flanking region, C-terminal, IPR013032=EGF-like, conserved site, IPR001881=EGF-like calcium-binding domain, IPR001611=Leucine-rich repeat, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR000372=Leucine-rich repeat N-terminal domain, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site" CG43758 16-Dec-15 2015_12 "ENSDARG00000034268(slit3),ENSDARG00000004246(slit2),ENSDARG00000044954(LOC100331185)" WBGene00004854(slt-1) "ENSXETG00000020473(SLIT2),ENSXETG00000003405(SLIT1),ENSXETG00000013676(SLIT3)" "ENSMUSG00000031558(Slit2),ENSMUSG00000056427(Slit3),ENSMUSG00000025020(Slit1)" "ENSG00000145147(SLIT2),ENSG00000184347(SLIT3),ENSG00000187122(SLIT1)" " embryonic stage | extended germ band , embryonic stage | stage 17 , embryonic stage | stage 15 , embryonic stage | stage 10 , embryonic stage | stage 13 , embryonic stage | gastrula , embryonic stage | stage 6 " " mesectoderm &&of ventral midline

, neuropil

, cardioblast

, ectoderm | lateral

segmentally repeated , embryonic central nervous system | restricted

, ectoderm | presumptive

, midline glial cell

" " embryonic stage | gastrula , embryonic stage | extended germ band , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage 13-16 , embryonic stage | stage 13-15 " " ventral midline &&of mesectoderm

, cardioblast

, midline glial cell

, neuron &&of embryonic central nervous system

, ventral midline

, epidermis | dorsal & lateral

, longitudinal connective | restricted

" FBgn0053860 His3:CG33860 His3:CG33860 http://flybase.net/reports/FBgn0053860.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33860 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33860 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053847 His2A:CG33847 His2A:CG33847 http://flybase.net/reports/FBgn0053847.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33847 "IPR002119=Histone H2A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33847 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0013981 His4r Histone H4 replacement http://flybase.net/reports/FBgn0013981.html FBgn0064800 protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006352=DNA-templated transcription, initiation, 0051298=centrosome duplication, 0006333=chromatin assembly or disassembly" "0005811=lipid particle, 0005634=nucleus, 0000786=nucleosome" "BcDNA:RH52884, FBtr0082962, His4-88CD, H4r, His4R, CG3379" "IPR001951=Histone H4, IPR019809=Histone H4, conserved site, IPR009072=Histone-fold, IPR004823=TATA box binding protein associated factor (TAF)" CG3379 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" DRSC16703 IEK -3.755480914 -2.396585983 -3.980870015 -7.573715726 -4.210531337 -2.537249305 FBgn0266354 CG45002 http://flybase.net/reports/FBgn0266354.html "FBgn0085355, FBgn0030810, FBgn0063269" protein_coding_gene "0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0016020=membrane "BcDNA:GH06235, CG34326, CG9059" "IPR002469=Dipeptidylpeptidase IV, N-terminal domain, IPR029058=Alpha/Beta hydrolase fold, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain" CG45002 16-Dec-15 2015_12 ENSDARG00000024744(dpp6b) WBGene00001054(dpf-1) "ENSXETG00000006574(DPP6),ENSXETG00000009512(),ENSXETG00000000625(DPP10)" FBgn0030795 ppk28 pickpocket 28 http://flybase.net/reports/FBgn0030795.html protein_coding_gene 0005272=sodium channel activity "0071462=cellular response to water stimulus, 0009415=response to water, 0042756=drinking behavior, 0006814=sodium ion transport" 0016021=integral component of membrane "CG4805, PPK28" "IPR001873=Na+ channel, amiloride-sensitive" CG4805 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" WBGene00006832(unc-105) "ENSXETG00000022398(ACCN5),ENSXETG00000013366(ACCN3),ENSXETG00000014229(ACCN1)" "ENSMUSG00000020704(Accn1),ENSMUSG00000023017(Accn2),ENSMUSG00000038276(Accn3),ENSMUSG00000033007(Accn4),ENSMUSG00000028008(Accn5)" "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" "neurophysiology defective,taste perception defective,proboscis extension reflex defective,viable" labellar taste bristle FBgn0002985 odd odd skipped http://flybase.net/reports/FBgn0002985.html FBgn0010502 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0016348=imaginal disc-derived leg joint morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007366=periodic partitioning by pair rule gene, 0007443=Malpighian tubule morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "odd-skipped, oddskipped, odd paired, Odd-Skipped, ODD, CG3851, Odd-skipped, l(2)01863, Odd, ODD-SKIPPED, Odd skipped, ods, Odd Skipped" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG3851 16-Dec-15 2015_12 "YPR015C(),YPR013C()" "ENSG00000103199(ZNF500),ENSG00000140265(ZSCAN29),ENSG00000155592(ZKSCAN2),ENSG00000140987(ZNF434),ENSG00000166261(ZNF202),ENSG00000121903(ZSCAN20),ENSG00000173258(ZNF483),ENSG00000186814(ZSCAN30),ENSG00000085644(ZNF213),ENSG00000006194(ZNF263),ENSG00000198315(ZNF192),ENSG00000106261(ZKSCAN1),ENSG00000196345(ZNF167),ENSG00000197037(ZNF498),ENSG00000189298(ZKSCAN3),ENSG00000167840(ZNF232),ENSG00000197657,ENSG00000166529(ZSCAN21),ENSG00000187626(ZKSCAN4),ENSG00000173275(ZNF449),ENSG00000196652(ZKSCAN5),ENSG00000182318(ZSCAN22),ENSG00000154957(ZNF18),ENSG00000160908(ZNF394),ENSG00000186376(ZNF75D),ENSG00000149054(ZNF215),ENSG00000197279(ZNF165),ENSG00000187987(ZSCAN23),ENSG00000172006(ZNF554),ENSG00000186496(ZNF396),ENSG00000103343(ZNF174),ENSG00000196812(ZSCAN16),ENSG00000137185(ZNF193),ENSG00000162714(ZNF496),ENSG00000197213(ZSCAN5B),ENSG00000204532,ENSG00000169951(ZNF764),ENSG00000131848(ZSCAN5A),ENSG00000083838(ZNF446),ENSG00000171606(ZNF274),ENSG00000170265(ZNF282)" " embryonic stage | stage 6-9 , embryonic stage | stage 4 , embryonic stage | stage >=6 , embryonic stage | late , embryonic stage | stage 5 , pupal stage , larval stage | third instar " "

segment polarity , organism | 60% egg length

, garland cell

, organism | pair rule

, Malpighian tubule

, leg | restricted

, ventral nerve cord

, embryonic/larval proventriculus

, organism | 90-100% egg length

, pericardial cell

, embryonic brain

, ventral thoracic disc | restricted

, pharyngeal muscle

" "visible,partially lethal - majority die,lethal,recessive,pair rule phenotype,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,segment polarity phenotype,somatic clone" "adult thorax,pupal thorax,embryonic abdominal segment 1,anterior,embryonic abdominal segment 3,embryonic abdominal segment 5,embryonic abdominal segment 7,embryonic segment,mouth hooks,dental sclerite,denticle belt,embryonic/first instar larval cuticle,embryonic head,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 9 ventral denticle belt,mesothoracic ventral denticle belt,embryonic labial segment,embryonic maxillary segment,tarsal segment 2,somatic clone,tarsal segment 3,tarsal segment 4,metatarsus,tarsal segment,segment,apodeme,pretarsus,mesothoracic segment & embryonic epidermis,abdominal segment 1 & embryonic epidermis,abdominal segment 3 & embryonic epidermis,abdominal segment 5 & embryonic epidermis,abdominal segment 7 & embryonic epidermis,leg & adult cuticleptc-559.1,ventral thoracic disc,leg & adult cuticle | somatic clone" FBgn0037345 rev7 rev7 http://flybase.net/reports/FBgn0037345.html protein_coding_gene "0051349=positive regulation of lyase activity, 0051726=regulation of cell cycle" "mad2B, Rev7, DmREV7, CG2948" IPR003511=HORMA domain CG2948 16-Dec-15 2015_12 "ENSDARG00000007096(si:dkey-23c22.2),ENSDARG00000042456(LOC557968)" ENSXETG00000013095(Q6GL56_XENTR) ENSMUSG00000029003(Mad2l2) ENSG00000116670(MAD2L2) "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0262740 Evi5 Ecotropic viral integration site 5 ortholog (H. sapiens) http://flybase.net/reports/FBgn0262740.html "FBgn0030299, FBgn0046801, FBgn0047215, FBgn0086552" protein_coding_gene "0005096=GTPase activator activity, 0017137=Rab GTPase binding" "0007298=border follicle cell migration, 0043087=regulation of GTPase activity" 0031982=vesicle "BcDNA:GH08923, CG11727, mRNA-like ncRNA in embryogenesis 21, BcDNA:LD11130, MRE21" IPR000195=Rab-GTPase-TBC domain CG11727 16-Dec-15 2015_12 "ENSDARG00000052766(si:ch211-239f4.1),ENSDARG00000070838,ENSDARG00000070839" "YPL249C(GYP5),YMR192W(GYL1)" ENSXETG00000022868(EVI5L) "ENSMUSG00000011832(Evi5l),ENSMUSG00000011831(Evi5)" "ENSG00000142459(EVI5L),ENSG00000067208(EVI5)" FBgn0028734 Fmr1 Fmr1 http://flybase.net/reports/FBgn0028734.html "FBgn0037787, FBgn0047258" protein_coding_gene "0043621=protein self-association, 0005515=protein binding, 0003729=mRNA binding, 0003723=RNA binding" "0045571=negative regulation of imaginal disc growth, 0050808=synapse organization, 0042331=phototaxis, 0007420=brain development, 0008582=regulation of synaptic growth at neuromuscular junction, 0051028=mRNA transport, 0007294=germarium-derived oocyte fate determination, 0006417=regulation of translation, 0008345=larval locomotory behavior, 0007349=cellularization, 0050976=detection of mechanical stimulus involved in sensory perception of touch, 0007411=axon guidance, 0097091=synaptic vesicle clustering, 0048134=germ-line cyst formation, 0008049=male courtship behavior, 0050807=regulation of synapse organization, 0007614=short-term memory, 0040011=locomotion, 0009794=regulation of mitotic cell cycle, embryonic, 0008355=olfactory learning, 0048814=regulation of dendrite morphogenesis, 0070142=synaptic vesicle budding, 0017148=negative regulation of translation, 0007268=synaptic transmission, 0050802=circadian sleep/wake cycle, sleep, 0007409=axonogenesis, 0002052=positive regulation of neuroblast proliferation, 0007413=axonal fasciculation, 0045448=mitotic cell cycle, embryonic, 0006935=chemotaxis, 0007310=oocyte dorsal/ventral axis specification, 0048813=dendrite morphogenesis, 0050774=negative regulation of dendrite morphogenesis, 0051964=negative regulation of synapse assembly, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0045475=locomotor rhythm, 0072375=medium-term memory, 0007528=neuromuscular junction development, 0046627=negative regulation of insulin receptor signaling pathway, 0046959=habituation, 0042127=regulation of cell proliferation, 0007279=pole cell formation, 0007281=germ cell development, 0007416=synapse assembly, 0016319=mushroom body development, 0051823=regulation of synapse structural plasticity, 0031507=heterochromatin assembly, 0007623=circadian rhythm, 1900073=regulation of neuromuscular synaptic transmission, 0007269=neurotransmitter secretion, 0007288=sperm axoneme assembly, 0007616=long-term memory, 0048812=neuron projection morphogenesis, 0090328=regulation of olfactory learning" "0016442=RISC complex, 0005737=cytoplasm, 0005811=lipid particle, 0035068=micro-ribonucleoprotein complex" "CG6203, fragile X mental retardation 1, Fragile X-related, dFXRP, Fragile X, cg6203, dFmrp, Fragile X mental retardation gene, dfmr1, Fragile X Mental Retardation, Fragile X mental retardation, Fragile-X-related, dFXR1, fragile x related, fmr, EP(3)3517, Fragile-X Mental Retardation protein, Fragile X mental retardation protein 1, Fragile X protein, Fragile X mental retardation protein, Fmrp, dfxr1, dFmr1, Fragile X Mental Retardation Protein, dFMRP, Fragile X related protein, Fragile X related, fragile X protein, dFMR1, dfmr, fragile X, dFMR, fmr1, AT24755, fragile X mental retardation protein, BcDNA:GM08679, FMRP, FMRp, FXR, fragile-X, FMR, Drosophila fragile X mental retardation protein, dFXR, FMR1, dfxr, dmfr1" "IPR022967=RNA-binding domain, S1, IPR022034=Fragile X-related 1 protein core, C-terminal, IPR004087=K Homology domain, IPR008395=Agenet-like domain, IPR004088=K Homology domain, type 1" CG6203 16-Dec-15 2015_12 "ENSDARG00000016260(LOC100330627),ENSDARG00000022968(fxr1),ENSDARG00000037433(fmr1)" "ENSXETG00000019647(fmr1),ENSXETG00000019441(frx1)" "ENSMUSG00000027680(Fxr1),ENSMUSG00000018765(Fxr2),ENSMUSG00000000838(Fmr1)" "ENSG00000129245(FXR2),ENSG00000114416(FXR1),ENSG00000102081(FMR1)" " pupal stage&&adult stage , adult stage , pupal stage " " neuron

, adult brain

, brain

" "neurophysiology defective,endomitotic cell cycle defective,memory defective,neuroanatomy defective,learning defective,viable,flight defective,fertile,recessive,lethal - all die before end of P-stage,partially,some die during pharate adult stage,locomotor rhythm defective,lethal,visible,courtship behavior defective,dominant,semidominant,eclosion rhythm defective,partially lethal - majority live,wild-type,semi-sterile,sleep defective,somatic clone,male sterile,locomotor behavior defective,male,mitotic cell cycle defective,partially lethal - majority die,maternal effect,some die during embryonic stage,suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,flightless,uncoordinated,some die during immature adult stage,increased cell death,temperature conditional,short lived,gravitaxis defective,conditional,heat stress response defective,heat sensitive,touch sensitivity defective,touch perception defective" "nurse cell,supernumerary,egg chamber,mushroom body beta-lobe,LNv neuron,rhabdomere R7,ventral adult lateral neuron & commissure[-],eye,ommatidium,synapse,neuromuscular junction & synapse,mushroom body alpha-lobe,embryonic/larval neuromuscular junction,NMJ bouton,adult mushroom body,dorsal cluster neuron & neurite[-],dorsal cluster neuron,neuron & beta-lobe,neuron & beta-lobe, with Fmr13,ventral adult lateral neuron & commissure,dorsal cluster neuron & neurite,retina,photoreceptor cell & synapse & lamina receptor cell,neuromuscular junction,testis,spermatid,spermatid axoneme,dorsal multidendritic neuron ddaC,mushroom body & neuron | somatic clone,mushroom body & neuron & dendrite | somatic clone,gamma-lobe & neuron | somatic clone,bouton,somatic clone,synaptic vesicle | somatic clone | supernumerary,s-LNv Pdf neuron,protocerebrum,axonemal microtubule,synapse, with Fmr1UAS.cZa, P2.4.Pdf,mechanosensory neuron,axon | ectopic,type I bouton,dendritic arborizing neuron,synapse & larval neuromuscular junction,germline cell,pole cell,pole bud,nucleus | embryonic cycle 13,condensed chromosome | embryonic stage,centrosome | embryonic stage,germline clone,maternal effect,germ cell & egg chamber,oocyte,ectopic,cycle 12 embryo,cycle 13 embryo,neuron & beta-lobe, with Fmr1I244N,neuron & beta-lobe, with Fmr1I307N,dorsal cluster neuron & neuriteato.3.6,rhabdomerehs.2sev,wing,photoreceptor cell,photoreceptor cell & synapse & lamina receptor cellhs.2sev,wing cell,anterior crossvein,wing margin,eye photoreceptor cell,pigment cell,mushroom body gamma-lobe,mushroom body & neuron | somatic cloneey-OK107,mushroom body & neuron & dendrite | somatic cloneey-OK107,gamma-lobe & neuron | somatic cloneey-OK107,neuromuscular junctionMhc.PW,synapseP2.4.Pdf,adult mushroom body beta'-lobe,synapse, with Fmr1ëÓ50M, P2.4.Pdf,adult brain,conditional" FBgn0038303 SIDL Shal Interactor of Di-Leucine Motif http://flybase.net/reports/FBgn0038303.html protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity "0006891=intra-Golgi vesicle-mediated transport, 0043087=regulation of GTPase activity" 0030008=TRAPP complex CG6623 "IPR021773=Foie gras liver health family 1, IPR022233=TRAPP II complex, TRAPPC10" CG6623 16-Dec-15 2015_12 YMR218C(TRS130) WBGene00022138(Y71G12A.2) ENSXETG00000018000(TRAPPC10) ENSMUSG00000000374(Trappc10) ENSG00000160218(TRAPPC10) FBgn0053827 His3:CG33827 His3:CG33827 http://flybase.net/reports/FBgn0053827.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33827 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG33827 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053854 His3:CG33854 His3:CG33854 http://flybase.net/reports/FBgn0053854.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33854 "IPR000164=Histone H3/CENP-A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33854 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053893 His4:CG33893 His4:CG33893 http://flybase.net/reports/FBgn0053893.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33893 "IPR001951=Histone H4, IPR019809=Histone H4, conserved site, IPR009072=Histone-fold" CG33893 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0011715 Snr1 Snf5-related 1 http://flybase.net/reports/FBgn0011715.html FBgn0010744 protein_coding_gene "0070984=SET domain binding, 0003713=transcription coactivator activity, 0005515=protein binding" "0007517=muscle organ development, 0006357=regulation of transcription from RNA polymerase II promoter, 0008587=imaginal disc-derived wing margin morphogenesis, 0043044=ATP-dependent chromatin remodeling, 0002165=instar larval or pupal development, 0070983=dendrite guidance, 0045893=positive regulation of transcription, DNA-templated, 0008544=epidermis development, 0006355=regulation of transcription, DNA-templated, 0001700=embryonic development via the syncytial blastoderm, 0048813=dendrite morphogenesis, 0008285=negative regulation of cell proliferation, 0007474=imaginal disc-derived wing vein specification, 0008586=imaginal disc-derived wing vein morphogenesis" "0070604=PBAF complex, 0005634=nucleus, 0000228=nuclear chromosome, 0035060=brahma complex" "Snr1/BAP45, BAP45, snr-1, SNR1, snf5-related 1, CG1064, Snr, l(3)01319, snr, snr1" "IPR006939=SNF5/SMARCB1/INI1, IPR017393=SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1" CG1064 16-Dec-15 2015_12 "ENSDARG00000033647(smarcb1a),ENSDARG00000011594(smarcb1b)" YBR289W(SNF5) WBGene00011111(snfc-5) ENSXETG00000022368(SNF5_XENTR) ENSMUSG00000000902(Smarcb1) ENSG00000099956(SMARCB1) " embryonic stage--pupal stage , adult stage | female , embryonic stage -- adult stage ," unfertilized egg

" embryonic stage | early , embryonic stage | stage >=13 , larval stage | third instar , larval stage , adult stage | female , embryonic stage--pupal stage " "

ubiquitous , embryonic brain

, larval optic lobe | restricted

, imaginal disc

, embryonic/larval salivary gland

, dorsal mesothoracic disc | restricted

, larval salivary gland

, embryonic central nervous system

, eye disc

, germarium region 2 && germarium region 3

, ventral thoracic disc | restricted

" "lethal - all die before end of second instar larval stage,hyperplasia,lethal - all die before end of P-stage,lethal,recessive,lethal - all die before end of embryonic stage,neuroanatomy defective,cell shape defective,lethal - all die before end of larval stage,some die during larval stage,suppressor of variegation,dominant,heat sensitive,visible,short lived,female sterile,cell lethalcell lethal,somatic clone,germline clone,body color defective,large body,viable,non-enhancer of variegation,non-suppressor of variegation,increased cell size,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval brain,adult antennal lobe projection neuron DL1 adPN,tergite,wing,wing vein,ectopic,mechanosensory chaeta & adult abdomen | somatic clone,mechanosensory chaeta | supernumerary & adult abdomen | somatic clone,socket & adult abdomen | somatic clone,adult cuticle,somatic clone,eye,adult thorax | dorsal & chaeta | somatic clone,heat sensitive,wing vein L2,wing sensillum,wing margin,wing hair,type II neuroblast,supernumerary" FBgn0025729 tra2::Hsap\SRSF2 SFRS2 http://flybase.net/reports/FBgn0025729.html engineered_fusion_gene "TRA-2/SC35, tra2::Hsap\SFRS2" 16-Dec-15 2015_12 FBgn0042168 CG18848 http://flybase.net/reports/FBgn0042168.html protein_coding_gene 16-Dec-15 2015_12 FBgn0040908 CG12687 http://flybase.net/reports/FBgn0040908.html protein_coding_gene 16-Dec-15 2015_12 FBgn0263631 mir-3645 mir-3645 stem loop http://flybase.net/reports/FBgn0263631.html "FBgn0262135, FBgn0263540" miRNA_gene CR43525 CR43525 16-Dec-15 2015_12 viable FBgn0030067 Rbm13 RNA-binding motif protein 13 http://flybase.net/reports/FBgn0030067.html protein_coding_gene "0022008=neurogenesis, 0000022=mitotic spindle elongation, 0040018=positive regulation of multicellular organism growth" "CG10648, RBM13" "IPR006958=Mak16 protein, IPR029004=Ribosomal L28e/Mak16" CG10648 16-Dec-15 2015_12 ENSDARG00000003527(LOC100334042) YAL025C(MAK16) WBGene00015811(C16A3.6) ENSXETG00000016495(RBM13_XENTR) ENSMUSG00000031578(Mak16) ENSG00000198042(MAK16) "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0003961 Uro Urate oxidase http://flybase.net/reports/FBgn0003961.html FBgn0044662 protein_coding_gene 0004846=urate oxidase activity "0019428=allantoin biosynthetic process, 0055114=oxidation-reduction process, 0045471=response to ethanol, 0006144=purine nucleobase metabolic process" 0005777=peroxisome "urate oxidase, UOX, Dm UO, OU, UO, anon-WO0140519.210, CG7171, Uo, uro" "IPR019842=Uricase, conserved site, IPR002042=Uricase" CG7171 16-Dec-15 2015_12 ENSDARG00000007024(uox) ENSXETG00000008648(Q5I0T2_XENTR) ENSMUSG00000028186(Uox) " larval stage , larval stage | third instar , adult stage " Malpighian tubule

larval stage | third instar Malpighian tubule

"viable,fertile" FBgn0036738 CG7542 http://flybase.net/reports/FBgn0036738.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP71 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG7542 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable DRSC10868 K 0.039255786 0.028356441 -0.212517686 0.422996093 1.592518254 2.211284358 FBgn0036411 Sox21a Sox21a http://flybase.net/reports/FBgn0036411.html FBgn0043568 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006909=phagocytosis, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Sox21, Sox B2-3, SoxB2.3, CG7345, SOXB2.3" IPR009071=High mobility group box domain CG7345 16-Dec-15 2015_12 YKL032C(IXR1) WBGene00004771(sem-2) "ENSXETG00000010955(SOX21),ENSXETG00000022689(SOX14)" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC10819 K -0.716720598 -0.281352836 -0.747475334 1.388741686 0.046036817 1.590380703 FBgn0004868 Gdi GDP dissociation inhibitor http://flybase.net/reports/FBgn0004868.html "FBgn0010224, FBgn0014258" protein_coding_gene "0005092=GDP-dissociation inhibitor activity, 0005093=Rab GDP-dissociation inhibitor activity" "0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0015031=protein transport" "0008021=synaptic vesicle, 0005829=cytosol, 0005875=microtubule associated complex" "GdI, Gdi-related, dGDI, Rab GDP dissociation inhibitor, lincRNA.S746, CG4422, N7-3, l(2)N7-3, GDI, rab GDI, rab GDP dissociation inhibitor" "IPR018203=GDP dissociation inhibitor, IPR000806=Rab GDI protein" CG4422 16-Dec-15 2015_12 "ENSDARG00000056122(gdi1),ENSDARG00000005451(gdi2)" YER136W(GDI1) WBGene00001558(gdi-1) "ENSXETG00000009337(),ENSXETG00000018149(gdi3),ENSXETG00000003376(GDI1)" "ENSMUSG00000015291(Gdi1),ENSMUSG00000021218(Gdi2)" "ENSG00000203879(GDI1),ENSG00000057608(GDI2)" "lethal,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "pole cell,embryonic epidermis,germline clone,puparium,melanotic mass,trichogen cell,mesothoracic tergum" FBgn0030474 CG15747 http://flybase.net/reports/FBgn0030474.html protein_coding_gene "0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome" IPR018612=Domain of unknown function DUF2040 CG15747 16-Dec-15 2015_12 ENSDARG00000015221(zgc:152777) WBGene00007627(ccdc-55) ENSXETG00000017949(CCDC55) ENSG00000126653(NSRP1) FBgn0037341 CG12746 http://flybase.net/reports/FBgn0037341.html protein_coding_gene 0008195=phosphatidate phosphatase activity "0006644=phospholipid metabolic process, 0016311=dephosphorylation" 0016020=membrane "PPAPDC1, WUN-like" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG12746 16-Dec-15 2015_12 "ENSDARG00000057672(ppapdc1b),ENSDARG00000067798" YDR284C(DPP1) "ENSXETG00000015185(PPAPDC1B),ENSXETG00000009592(PPAPDC1A)" "ENSMUSG00000031570(Ppapdc1b),ENSMUSG00000070366(Ppapdc1a)" "ENSG00000203805(PPAPDC1A),ENSG00000147535(PPAPDC1B)" "viable,fertile" FBgn0053897 His4:CG33897 His4:CG33897 http://flybase.net/reports/FBgn0053897.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33897 "IPR009072=Histone-fold, IPR019809=Histone H4, conserved site, IPR001951=Histone H4" CG33897 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" DRSC30020 IEK -3.179513886 -3.964253834 -1.486507778 -5.104496797 -2.504067021 0.541527032 FBgn0036813 Atg3 Autophagy-related 3 http://flybase.net/reports/FBgn0036813.html protein_coding_gene "0019787=ubiquitin-like protein transferase activity, 0019776=Atg8 ligase activity" "0006914=autophagy, 1902350=cellular response to chloroquine, 0035096=larval midgut cell programmed cell death" 0005829=cytosol "CG6877, Autophagy-specific gene 3, Atg3, Aut-1, Draut1, AUT1, atg3, Aut1" "IPR007135=Autophagy-related protein 3, IPR019461=Autophagy-related protein 3, C-terminal, IPR007134=Autophagy-related protein 3, N-terminal" CG6877 16-Dec-15 2015_12 ENSDARG00000009350(apg3l) YNR007C(ATG3) WBGene00021922(atg-3) ENSXETG00000002424(apg3l) ENSMUSG00000022663(Atg3) ENSG00000144848(ATG3) "viable,partially lethal - majority die,heat sensitive,lethal,fertile" "autophagic vacuole,embryonic/larval fat body" DRSC29687 K -0.541232223 0.371725853 0.645217718 -0.026466699 0.311136432 1.705667528 FBgn0030028 Corp Companion of reaper http://flybase.net/reports/FBgn0030028.html protein_coding_gene 0008630=intrinsic apoptotic signaling pathway in response to DNA damage "corp, CG10965, companion of reaper" CG10965 16-Dec-15 2015_12 pupal stage salivary gland

"partially lethal - majority die,some die during pupal stage" DRSC17771 K -0.643252825 -0.397576893 -0.510746001 -0.089154985 1.778323333 0.604168559 FBgn0259143 CG42258 http://flybase.net/reports/FBgn0259143.html "FBgn0062447, FBgn0030393, FBgn0030392" protein_coding_gene 0005886=plasma membrane "Pripl4, CG17788, CG15926, BcDNA:RE29468" CG42258 16-Dec-15 2015_12 DRSC19741 E 1.389771436 1.430670765 1.553865835 1.077260489 0.638831854 -0.241470646 FBgn0026084 cib ciboulot http://flybase.net/reports/FBgn0026084.html protein_coding_gene "0003779=actin binding, 0003785=actin monomer binding" "0035193=larval central nervous system remodeling, 0007420=brain development, 0007015=actin filament organization" 0005829=cytosol "Ciboulout, beta-thymosin, EG0007-11, EG:EG0007.11, Ciboulot, ciboulet, CG4944" IPR001152=Beta-thymosin CG4944 16-Dec-15 2015_12 WBGene00006649(tth-1) "viable,body color defective" "ellipsoid body,mushroom body beta-lobe,mesothoracic tergum" DRSC18660 K -0.143367977 0.425297082 -0.110915794 0.227366776 -0.025248372 -2.979034378 FBgn0262560 wcd wicked http://flybase.net/reports/FBgn0262560.html "FBgn0022070, FBgn0034119, FBgn0086729" protein_coding_gene "0007405=neuroblast proliferation, 0006364=rRNA processing, 0022008=neurogenesis, 0048132=female germ-line stem cell asymmetric division" "0005730=nucleolus, 0042585=germinal vesicle, 0005634=nucleus, 0030532=small nuclear ribonucleoprotein complex" "wicked, l(2)k07824, Wcd, CG7989, Wicked, lethal (2) k07824, l(2)kO7824" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG7989 16-Dec-15 2015_12 YJL069C(UTP18) WBGene00015104(B0280.9) ENSXETG00000001293(wdr50) ENSMUSG00000054079(Utp18) ENSG00000011260(UTP18) DRSC07051 K -0.292753859 0.234427536 -0.112888853 0.140663539 -0.525729232 1.548139505 FBgn0053907 His4:CG33907 His4:CG33907 http://flybase.net/reports/FBgn0053907.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33907 "IPR019809=Histone H4, conserved site, IPR009072=Histone-fold, IPR001951=Histone H4" CG33907 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0010435 emp epithelial membrane protein http://flybase.net/reports/FBgn0010435.html protein_coding_gene 0005044=scavenger receptor activity "0048102=autophagic cell death, 0007155=cell adhesion, 0006952=defense response, 0035071=salivary gland cell autophagic cell death" "0005764=lysosome, 0005887=integral component of plasma membrane, 0005886=plasma membrane" "Epithelial membrane protein, CG2727" "IPR002159=CD36 antigen, IPR005429=Lysosome membrane protein II, IPR005428=Adhesion molecule CD36" CG2727 16-Dec-15 2015_12 "ENSDARG00000021279(scarb2),ENSDARG00000059295,ENSDARG00000054983" "WBGene00013039(scav-3),WBGene00013578(scav-2)" ENSMUSG00000037936(Scarb1) "ENSG00000073060(SCARB1),ENSG00000138760(SCARB2)" " pupal stage | early , embryonic stage | >=6 hr , larval stage | third instar , embryonic stage | stage 13 " " imaginal disc

, embryonic/larval hindgut | restricted

, embryonic/larval foregut | restricted

, peripodial epithelium &&of dorsal mesothoracic disc

, dorsal mesothoracic disc | restricted

, ectoderm

, epidermis

, embryonic/larval tracheal system

" viable FBgn0019928 Ser8 Ser8 http://flybase.net/reports/FBgn0019928.html FBgn0033838 protein_coding_gene "0008236=serine-type peptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "SP90, SP#3, Serine Protease 3, CG4812, SP3" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG4812 16-Dec-15 2015_12 "ENSDARG00000042993(try),ENSDARG00000040282(zgc:92590),ENSDARG00000068303(zgc:171509),ENSDARG00000070335" viable FBgn0031238 CG3645 http://flybase.net/reports/FBgn0031238.html protein_coding_gene "0050660=flavin adenine dinucleotide binding, 0017150=tRNA dihydrouridine synthase activity" "0055114=oxidation-reduction process, 0008033=tRNA processing" "IPR018517=tRNA-dihydrouridine synthase, conserved site, IPR001269=tRNA-dihydrouridine synthase, IPR013785=Aldolase-type TIM barrel" CG3645 16-Dec-15 2015_12 ENSDARG00000012160 YML080W(DUS1) WBGene00009452(F36A2.2) ENSXETG00000019654(DUS1L) ENSMUSG00000025155(Dus1l) ENSG00000169718(DUS1L) "viable,fertile" FBgn0026147 CG16833 http://flybase.net/reports/FBgn0026147.html FBgn0032327 protein_coding_gene 0004835=tubulin-tyrosine ligase activity "0018095=protein polyglutamylation, 0042060=wound healing" "LD13681, BEST:LD13681" "IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027748=Tubulin polyglutamylase TTLL-4" CG16833 16-Dec-15 2015_12 WBGene00014232(ttll-4) ENSXETG00000013887(TTLL4) ENSMUSG00000033257(Ttll4) ENSG00000135912(TTLL4) viable FBgn0031910 CG15818 http://flybase.net/reports/FBgn0031910.html protein_coding_gene 0030246=carbohydrate binding "IPR001304=C-type lectin, IPR016187=C-type lectin fold, IPR016186=C-type lectin-like" CG15818 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" "WBGene00020585(clec-178),WBGene00018692(F52E1.2)" ENSXETG00000001204(COLEC11) "ENSMUSG00000040963(Asgr2),ENSMUSG00000020884(Asgr1),ENSMUSG00000000318(Clec10a),ENSMUSG00000040950(Mgl2),ENSMUSG00000036103(Colec12),ENSMUSG00000034783(Cd207)" "ENSG00000118004(COLEC11),ENSG00000220191,ENSG00000165471(MBL2),ENSG00000184374(COLEC10),ENSG00000133661(SFTPD),ENSG00000182314,ENSG00000122854,ENSG00000122852(SFTPA1),ENSG00000185303(SFTPA2)" "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0053851 His3:CG33851 His3:CG33851 http://flybase.net/reports/FBgn0053851.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33851 "IPR000164=Histone H3/CENP-A, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33851 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0010501 Dcp-1 Death caspase-1 http://flybase.net/reports/FBgn0010501.html FBgn0010509 protein_coding_gene "0097200=cysteine-type endopeptidase activity involved in execution phase of apoptosis, 0004197=cysteine-type endopeptidase activity, 1990525=BIR domain binding, 0005515=protein binding" "0007303=cytoplasmic transport, nurse cell to oocyte, 0016322=neuron remodeling, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0048477=oogenesis, 0007300=ovarian nurse cell to oocyte transport, 0045476=nurse cell apoptotic process, 0009267=cellular response to starvation, 0010623=developmental programmed cell death, 0010508=positive regulation of autophagy, 0097194=execution phase of apoptosis, 0007015=actin filament organization, 0007275=multicellular organismal development, 0012501=programmed cell death, 1900074=negative regulation of neuromuscular synaptic transmission, 0006915=apoptotic process, 0016239=positive regulation of macroautophagy, 0006508=proteolysis" "0005829=cytosol, 0005739=mitochondrion" "dcp1, DCP-1, CG5370, l(2)02132, Dcp1, dcp-1, caspase 1, caspase, l(2)01862, death caspase-1, DCP1, caspase-1, ccp1" "IPR016129=Peptidase C14, ICE, catalytic subunit p20, active site, IPR015917=Peptidase C14A, caspase precursor p45, core, IPR011600=Peptidase C14, caspase domain, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR002138=Peptidase C14, caspase non-catalytic subunit p10, IPR029030=Caspase-like domain" CG5370 16-Dec-15 2015_12 "ENSDARG00000016228,ENSDARG00000017905(casp3a),ENSDARG00000055045(casp3b)" WBGene00000417(ced-3) "ENSXETG00000016471(casp7),ENSXETG00000001537(CASP3)" "ENSMUSG00000025076(Casp7),ENSMUSG00000031628(Casp3)" "ENSG00000165806(CASP7),ENSG00000164305(CASP3)" embryonic stage "increased cell death,cell death defective,neuroanatomy defective,neurophysiology defective,viable,visible,eye color defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell death,nutrition conditional,sterile" "egg chamber,follicle cell,neuron,eye,pigment cell,conditional,chaeta,supernumerary,eye disc,dendrite,germarium region 2,nutrition conditional,female germline cyst,spermatogonial cyst,male germline cell,actin filament & nurse cellnos.UTR.THsimVP16,outer photoreceptor cell" FBgn0028369 kirre kin of irre http://flybase.net/reports/FBgn0028369.html FBgn0028745 protein_coding_gene "0005515=protein binding, 0050839=cell adhesion molecule binding" "0061321=garland nephrocyte differentiation, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 1901739=regulation of myoblast fusion, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0001745=compound eye morphogenesis, 0036058=filtration diaphragm assembly, 0036059=nephrocyte diaphragm assembly, 0007523=larval visceral muscle development, 0016202=regulation of striated muscle tissue development, 0097206=nephrocyte filtration, 0007520=myoblast fusion" "0005917=nephrocyte diaphragm, 0005912=adherens junction, 0005886=plasma membrane, 0009986=cell surface" "Dumbfounded/Kirre, DUF, duf/kirre, CG3653, kin of irreC, EG:163A10.1, kirre, Kin of IrreC, dumbfounded, Duf/Kirre, kin-of-irreC, Kin of irre, RH09239, Kirre, Dumbfounded, duf, CT12279, Kin-of-irre, DUF/KIRRE, Kin of irregular-chiasm-C, Duf" "IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013162=CD80-like, immunoglobulin C2-set, IPR013106=Immunoglobulin V-set domain, IPR013098=Immunoglobulin I-set, IPR003599=Immunoglobulin subtype" CG3653 16-Dec-15 2015_12 "ENSDARG00000019473(kirrel3),ENSDARG00000060939(LOC572369),ENSDARG00000001634(kirrel),ENSDARG00000056998(si:ch211-195h23.2)" WBGene00006365(syg-1) ENSXETG00000001252() "ENSMUSG00000041734(Kirrel),ENSMUSG00000032036(Kirrel3),ENSMUSG00000036915(Kirrel2)" "ENSG00000183853(KIRREL),ENSG00000149571(KIRREL3),ENSG00000126259(KIRREL2)" "viable,fertile,visible,lethal,male fertile" "embryonic/larval garland cell,pericardial cell,filtration diaphragm,nucleus | supernumerary | third instar larval stage,wing margin,wing hair,embryonic/larval pericardial cell,myoblast,embryonic/larval garland cell | third instar larval stage,nucleus | supernumerary | third instar larval stagepros.PMG,eye,optic lobe,nucleus | supernumerarykirre.PR,ventral acute muscle 2,segment border muscle,ommatidium,inter-ommatidial cell,inter-ommatidial precursor cell,interommatidial bristle" FBgn0053848 His3:CG33848 His3:CG33848 http://flybase.net/reports/FBgn0053848.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33848 "IPR000164=Histone H3/CENP-A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33848 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0053808 His2A:CG33808 His2A:CG33808 http://flybase.net/reports/FBgn0053808.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0000786=nucleosome, 0005634=nucleus" CG33808 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A" CG33808 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0053838 His2A:CG33838 His2A:CG33838 http://flybase.net/reports/FBgn0053838.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33838 "IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A, IPR009072=Histone-fold" CG33838 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0053858 His1:CG33858 His1:CG33858 http://flybase.net/reports/FBgn0053858.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33858 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5" CG33858 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0002542 lds lodestar http://flybase.net/reports/FBgn0002542.html "FBgn0001050, FBgn0019956, FBgn0037532" protein_coding_gene "0005524=ATP binding, 0008094=DNA-dependent ATPase activity" "0006369=termination of RNA polymerase II transcription, 0007143=female meiotic division, 0006353=DNA-templated transcription, termination, 0007283=spermatogenesis, 0034454=microtubule anchoring at centrosome" "0005737=cytoplasm, 0005634=nucleus" "lod, early-5, Fs(3)Horka, early-B, Lds, Fs(3)Hor, Female sterile (3) Horka, NTef2, CG2684, Fs(3)Sz11, DmF2, factor 2, early, transcript A, Negative transcription elongation factor 2, Horka, early-3" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain" CG2684 16-Dec-15 2015_12 ENSDARG00000026053(LOC564651) YOR191W(ULS1) "WBGene00020742(T23H2.3),WBGene00010061(F54E12.2),WBGene00019095(F59A7.8)" ENSMUSG00000033222(Ttf2) ENSG00000116830(TTF2) " embryonic stage -- adult stage , oogenesis stage && adult stage | female " ovary

"wild-type,mitotic cell cycle defective,non-rescuable maternal effect,recessive,female sterile,male sterile,lethal,partially lethal - majority die,visible,dominant,meiotic cell cycle defective,paternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially" "mitosis & nuclear chromosome & embryo,nucleus | embryonic stage,spindle | embryonic stage,chromatin & mitotic anaphase,trichogen cell,male pronucleus | maternal effect,female pronucleus | maternal effect,centrosome,onion stage spermatid,individualization stage spermatid" FBgn0031065 CG14234 http://flybase.net/reports/FBgn0031065.html protein_coding_gene IPR025256=Domain of unknown function DUF4203 CG14234 16-Dec-15 2015_12 "ENSDARG00000034685(tmem198b),ENSDARG00000042115(tmem198a)" "ENSXETG00000021853(BC076677.1),ENSXETG00000014414(TMEM198)" "ENSMUSG00000051703(Tmem198),ENSMUSG00000047090(1110012D08Rik)" ENSG00000188760(TMEM198) viable FBgn0005649 Rox8 Rox8 http://flybase.net/reports/FBgn0005649.html "FBgn0010255, FBgn0010283" protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0000166=nucleotide binding, 0008143=poly(A) binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0005685=U1 snRNP" "TIAR, RNA-binding protein 12, DmTIAR, Rbp12, dTIAR, Rox-8, rrm12, CG5422, ROX8, rox8, RRM12" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG5422 16-Dec-15 2015_12 "ENSDARG00000026476(tia1l),ENSDARG00000052536(tia1),ENSDARG00000009525(tial1)" YNL016W(PUB1) "WBGene00015943(C18A3.5),WBGene00012904(Y46G5A.13)" "ENSXETG00000008514(tia1),ENSXETG00000010234(tial1)" "ENSMUSG00000071337(Tia1),ENSMUSG00000030846(Tial1)" "ENSG00000151923(TIAL1),ENSG00000116001(TIA1)" " adult stage | female , larval stage&&pupal stage&&adult stage , embryonic stage | early " "viable,fertile" DRSC16829 I -1.621786838 -0.253857938 -0.203477845 -1.4302837 0.348108194 0.256765805 FBgn0052500 CG32500 http://flybase.net/reports/FBgn0052500.html "FBgn0042218, FBgn0063180, FBtr0077374, FBpp0077066" protein_coding_gene "0005506=iron ion binding, 0051536=iron-sulfur cluster binding" 0016226=iron-sulfur cluster assembly "CG18856, BcDNA:GM32035" "IPR001075=NIF system FeS cluster assembly, NifU, C-terminal, IPR017065=NFU1 iron-sulfur cluster scaffold homologue, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014824=Scaffold protein Nfu/NifU, N-terminal" CG32500 16-Dec-15 2015_12 ENSDARG00000068125(hirip5) YKL040C(NFU1) WBGene00003064(lpd-8) ENSXETG00000008202(NFU1) ENSMUSG00000029993(Nfu1) ENSG00000169599(NFU1) FBgn0011606 Klp3A Kinesin-like protein at 3A http://flybase.net/reports/FBgn0011606.html "FBgn0000827, FBgn0002711, FBgn0010237, FBgn0040374" protein_coding_gene "0008017=microtubule binding, 0003777=microtubule motor activity, 0005524=ATP binding, 0008574=ATP-dependent microtubule motor activity, plus-end-directed" "0007131=reciprocal meiotic recombination, 0007059=chromosome segregation, 0090307=mitotic spindle assembly, 0007088=regulation of mitotic nuclear division, 0007018=microtubule-based movement, 0007338=single fertilization, 0051231=spindle elongation, 0016321=female meiosis chromosome segregation, 0007052=mitotic spindle organization, 0007110=meiosis I cytokinesis, 0007140=male meiosis, 0007067=mitotic nuclear division" "0005875=microtubule associated complex, 0051233=spindle midzone, 0030496=midbody, 0005871=kinesin complex, 0005819=spindle, 0005634=nucleus, 0005737=cytoplasm, 0005818=aster" "KIF 4A, mei-352, KIF4A, EG:BACR25B3.9, klp3a, DmKlp3A, Klp 3A, KLP-3A, CG8590, fs(1)M4, 3A7Kin, DmKLP3A, female sterile(1)M4, BcDNA:LD21815, KLP3A, meiotic 352, Kinesin-Like-Protein-at-3A, KIF4, Klp3a, klp3A" "IPR027640=Kinesin-like protein, IPR001752=Kinesin motor domain, IPR019821=Kinesin motor domain, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8590 16-Dec-15 2015_12 ENSDARG00000005462(zgc:66125) WBGene00002229(klp-19) ENSXETG00000005552(kif4a) ENSMUSG00000034311(Kif4) ENSG00000090889(KIF4A) embryonic stage -- adult stage " oogenesis stage , embryonic stage " "male sterile,partially,lethal - all die before end of embryonic stage,maternal effect,lethal,some die during embryonic stage,wild-type,female sterile,meiotic cell cycle defective,recessive,female semi-sterile,mitotic cell cycle defective,viable" "spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,contractile ring & meiotic cell cycle | male,spindle & meiotic cell cycle | male,spermatocyte ring canal,spermatid,meiotic cell cycle,Nebenkern,condensed nuclear chromosome | embryonic stage,spindle pole | embryonic stage,nucleus & telophase & embryo,spindle | embryonic stage" FBgn0023169 AMPKë± AMP-activated protein kinase ë± subunit http://flybase.net/reports/FBgn0023169.html "FBgn0004836, FBgn0029574" protein_coding_gene "0004703=G-protein coupled receptor kinase activity, 0004674=protein serine/threonine kinase activity, 0004679=AMP-activated protein kinase activity, 0005524=ATP binding" "0001558=regulation of cell growth, 0006909=phagocytosis, 0007165=signal transduction, 0007411=axon guidance, 0009267=cellular response to starvation, 0006468=protein phosphorylation, 0045792=negative regulation of cell size, 0044058=regulation of digestive system process, 0042331=phototaxis, 0042595=behavioral response to starvation, 0048813=dendrite morphogenesis, 0032007=negative regulation of TOR signaling, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0000278=mitotic cell cycle, 0006629=lipid metabolic process, 0030730=sequestering of triglyceride" "0005737=cytoplasm, 0005634=nucleus, 0031588=AMP-activated protein kinase complex" "adenosine monophosphate-activated protein kinase, AMP-dependent kinase, Gprk-4, snf1A, snf1a, dAMPKalpha, ampkalpha, CG3051, SNF1A/AMP-activated protein kinase, SNF1A, AMP-activated kinase, dAMPK, AMP activated kinase, FBgn0023169, Gprk4, AMPKalpha, G protein-coupled receptor kinase 4, EG:132E8.2, 5'monophosphate-activated kinase, AK, dAMPKa, DmAMPK alpha, AMPK, AMPK catalytic subunit, ampk, AmpKalpha, AMP-activated protein kinase" "IPR028375=KA1 domain/Ssp2 C-terminal domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR028783=5'-AMP-activated protein kinase catalytic subunit alpha-2, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG3051 16-Dec-15 2015_12 "ENSDARG00000060641,ENSDARG00000060596(prkaa1)" YDR477W(SNF1) WBGene00020142(aak-2) "ENSXETG00000011138(PRKAA2),ENSXETG00000007026(PRKAA1)" "ENSMUSG00000028518(Prkaa2),ENSMUSG00000050697(Prkaa1)" "ENSG00000162409(PRKAA2),ENSG00000132356(PRKAA1)" "long lived,RU486 conditional,viable,lethal,small body,developmental rate defective,stress response defective,dominant,lethal - all die before end of larval stage,some die during third instar larval stage,short lived,starvation stress response defective,neuroanatomy defective,some die during second instar larval stage,immune response defective,some die during larval stage,increased cell size,somatic clone,locomotor rhythm defective,nutrition conditional,hyperactive,feeding behavior defective,maternal effect,mitotic cell cycle defective,lethal - all die before end of second instar larval stage,recessive,cell polarity defective,cell cycle defective,cytokinesis defective" "hindgut muscle,midgut muscle,longitudinal visceral muscle fiber,circular visceral muscle fiber,hindgut visceral muscle fiber,embryonic/larval digestive system,embryonic/larval fat body,embryonic/larval midgut,dendritic arborizing neuron,plasma membrane | second instar larval stage,dendrite | second instar larval stage,sensory neuron,class IV dendritic arborizing neuron,oenocyte,follicle cell,embryonic/first instar larval cuticle,maternal effect,denticle belt,embryonic epidermis,neuroblast,spindle,centrosome" FBgn0000556 Ef1ë±48D Elongation factor 1ë±48D http://flybase.net/reports/FBgn0000556.html "FBgn0010480, FBgn0022092" protein_coding_gene "0003924=GTPase activity, 0003746=translation elongation factor activity, 0005525=GTP binding" "0006414=translational elongation, 0008340=determination of adult lifespan, 0006412=translation" "0005853=eukaryotic translation elongation factor 1 complex, 0005737=cytoplasm, 0005829=cytosol, 0005875=microtubule associated complex, 0005811=lipid particle" "EF1alpha 48D, clone 1.17, EF1alpha48D, clone 2.46, Ef1alpha48E, EF-1[a], F1, Dm0084, anon-EST:Liang-1.17, EF, EF1-alpha, EF-1alpha, chr2R:7409490..7409690, EF-1alphaF1, ef-1alpha, chr2R:7410009..7410129, F1 EF-1alpha, Ef1, Elongation factor 1 alpha, EF11_DROME, Ef1alpha48D, eEF1alpha, Elongation factor 1 alpha 48D, EF-1alphaF[[1]], EF1alpha, l(2)1275, Translational elongation factor1, elongation factor 1-alpha F1, Ef1a10, CG8280, Efalpha48D, Ef1alpha1, anon-EST:Liang-2.46, EF-1, Ef1a48D, EF-1alphaF, l(2)k07303, EF-1a, DmEF1, Elongation factor 1alpha48D, EF-1alpha F1, l(2)01275, 1275" "IPR009000=Translation protein, beta-barrel domain, IPR000795=Transcription factor, GTP-binding domain, IPR004539=Translation elongation factor EF1A, eukaryotic/archaeal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR031157=Tr-type G domain, conserved site, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR004160=Translation elongation factor EFTu/EF1A, C-terminal" CG8280 16-Dec-15 2015_12 "ENSDARG00000020850(ef1a),ENSDARG00000039502(zgc:73138),ENSDARG00000069951(zgc:110335),ENSDARG00000069952,ENSDARG00000006838(zgc:92085)" "YBR118W(TEF2),YPR080W(TEF1)" WBGene00001169(eft-4) "ENSXETG00000001182(EEF1A1),ENSXETG00000019567(Q5I0S9_XENTR),ENSXETG00000022604(eef1a1)" "ENSMUSG00000037742(Eef1a1),ENSMUSG00000016349(Eef1a2)" "ENSG00000156508(EEF1A1),ENSG00000101210(EEF1A2)" embryonic stage -- adult stage "lethal,recessive,female sterile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC07421 E -0.995900608 1.052734164 0.216388644 -3.506683545 -0.371330713 -0.598641108 FBgn0053873 His4:CG33873 His4:CG33873 http://flybase.net/reports/FBgn0053873.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33873 "IPR019809=Histone H4, conserved site, IPR001951=Histone H4, IPR009072=Histone-fold" CG33873 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0038975 Nrx-1 Neurexin 1 http://flybase.net/reports/FBgn0038975.html protein_coding_gene "0034185=apolipoprotein binding, 0097109=neuroligin family protein binding, 0046872=metal ion binding, 0005515=protein binding" "0007268=synaptic transmission, 2000331=regulation of terminal button organization, 0051124=synaptic growth at neuromuscular junction, 0050808=synapse organization, 0007416=synapse assembly, 1900073=regulation of neuromuscular synaptic transmission, 0007274=neuromuscular synaptic transmission, 0008306=associative learning, 1900244=positive regulation of synaptic vesicle endocytosis, 0071938=vitamin A transport, 0040012=regulation of locomotion" "0005886=plasma membrane, 0016021=integral component of membrane, 0031594=neuromuscular junction" "Neurexin-1, neurexin 1, dnrx, nrx, Drosophila neurexin, Neurexin-like, Nrx, dnrx-1, neurexin, Neurexin, CT21808, DNrx, dnrx1, CG7050, Nrx1" "IPR000742=EGF-like domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR027160=Neurexin-2" CG7050 16-Dec-15 2015_12 "ENSDARG00000061454(nrxn2a),ENSDARG00000043746(LOC100332109),ENSDARG00000061647(nrxn1a),ENSDARG00000063635(nrxn1b),ENSDARG00000063606(LOC100333083),ENSDARG00000062693" WBGene00007799(nrx-1) "ENSXETG00000011090(NRXN3),ENSXETG00000015575(NRXN2),ENSXETG00000018835()" "ENSMUSG00000066392(Nrxn3),ENSMUSG00000033768(Nrxn2),ENSMUSG00000024109(Nrxn1)" "ENSG00000021645(NRXN3),ENSG00000179915(NRXN1),ENSG00000110076(NRXN2)" "viable,fertile,short lived,locomotor behavior defective,neurophysiology defective,learning defective,phototaxis defective,neuroanatomy defective,uncoordinated,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuromuscular junction,bouton,synaptic vesicle,synapse,synapseExel6191),neuromuscular junction5C1),type I bouton,NMJ bouton,presynaptic active zone | supernumerary,subsynaptic reticulum,postsynaptic density,neuromuscular junction | larval stageExel6191),neuromuscular junction | embryonic stageExel6191),neuromuscular junction | embryonic stageelav.PLu" FBgn0036072 CG6628 http://flybase.net/reports/FBgn0036072.html protein_coding_gene 0005576=extracellular region "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG6628 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0043364 cbt cabut http://flybase.net/reports/FBgn0043364.html FBgn0031259 protein_coding_gene "0046872=metal ion binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding" "0048190=wing disc dorsal/ventral pattern formation, 0048592=eye morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007391=dorsal closure, 0090098=positive regulation of decapentaplegic signaling pathway, 0048102=autophagic cell death, 0007423=sensory organ development, 0035071=salivary gland cell autophagic cell death, 0001736=establishment of planar polarity, 0007390=germ-band shortening, 0007254=JNK cascade, 0045893=positive regulation of transcription, DNA-templated, 0007472=wing disc morphogenesis" 0005634=nucleus "dTIEG, TGF-beta-inducible early gene, cabot, CG4427, Cabut, Cabot, cabut, EP(2)2237, EP2237" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG4427 16-Dec-15 2015_12 "ENSDARG00000013794(klf11b),ENSDARG00000030844(klf11a)" "YPR015C(),YPR013C()" WBGene00013970(ZK337.2) "ENSXETG00000007013(TGas065a01.1),ENSXETG00000004120(KLF10)" "ENSG00000118922(KLF12),ENSG00000102349(KLF8)" "visible,increased cell number,partially lethal,conditional,developmental rate defective,neuroanatomy defective,viable,recessive,lethal - all die before end of embryonic stage,partially,some die during embryonic stage,cell polarity defective" "crossvein,1st posterior cell,wing,wing vein L5,wing margin,wing vein,wing pouch,wing disc,posterior compartment,dorsocentral bristle,scutellar bristle,ectopic,trichogen cell,tormogen cell,ocellus,anterior fascicle & synapse,neurite | pharate adult stage,embryonic/first instar larval cuticle,anterior,dorsal closure embryo,dorsal,embryonic leading edge cell,leading edge & filamentous actin,leading edge & muscle myosin complex,amnioserosa" FBgn0030521 CtsB1 Cathepsin B1 http://flybase.net/reports/FBgn0030521.html FBgn0026294 protein_coding_gene "0004197=cysteine-type endopeptidase activity, 0008233=peptidase activity" "0050790=regulation of catalytic activity, 0006508=proteolysis, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" 0098595=perivitelline space "CB, CTSB1, CG10992, Cathepsin B, cathepsin B, CG-10992, anon-EST:ParkEST132" "IPR000169=Cysteine peptidase, cysteine active site, IPR000668=Peptidase C1A, papain C-terminal, IPR025661=Cysteine peptidase, asparagine active site, IPR013128=Peptidase C1A, IPR025660=Cysteine peptidase, histidine active site, IPR012599=Peptidase C1A, propeptide" CG10992 16-Dec-15 2015_12 "ENSDARG00000055120(ctsba),ENSDARG00000067570(ctsbb)" "WBGene00000786(cpr-6),WBGene00010204(F57F5.1)" ENSXETG00000000671(ctsb) ENSMUSG00000021939(Ctsb) ENSG00000164733(CTSB) "viable,lethal,recessive" FBgn0033983 CG10253 http://flybase.net/reports/FBgn0033983.html protein_coding_gene "0008762=UDP-N-acetylmuramate dehydrogenase activity, 0071949=FAD binding, 0008609=alkylglycerone-phosphate synthase activity" "0008610=lipid biosynthetic process, 0008611=ether lipid biosynthetic process, 0055114=oxidation-reduction process" 0005777=peroxisome "dAGPS, alkyldihydroxyacetonephosphate synthase, ADPS" "IPR016169=CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR004113=FAD-linked oxidase, C-terminal, IPR016164=FAD-linked oxidase-like, C-terminal, IPR025650=Alkyldihydroxyacetonephosphate synthase, IPR016166=FAD-binding, type 2, IPR006094=FAD linked oxidase, N-terminal, IPR016167=FAD-binding, type 2, subdomain 1" CG10253 16-Dec-15 2015_12 ENSDARG00000042821(agps) YDL174C(DLD1) WBGene00000081(ads-1) ENSXETG00000008462(AGPS) ENSMUSG00000042410(Agps) ENSG00000018510(AGPS) viable FBgn0033339 Sec31 Sec31 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0033339.html protein_coding_gene 0005198=structural molecule activity "0090114=COPII-coated vesicle budding, 0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response" "0030134=ER to Golgi transport vesicle, 0030127=COPII vesicle coat, 0005795=Golgi stack, 0070971=endoplasmic reticulum exit site, 0008021=synaptic vesicle, 0005783=endoplasmic reticulum" "CG8266, sec31, dSec31p, Sec31, SEC31" "IPR024298=Ancestral coatomer element 1, Sec16/Sec31, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG8266 16-Dec-15 2015_12 "ENSDARG00000021082(sec31a),ENSDARG00000002916(sec31b)" YDL195W(SEC31) WBGene00011338(T01G1.3) "ENSXETG00000014203(SEC31B),ENSXETG00000000368(Q5U4X9_XENTR)" "ENSMUSG00000035325(Sec31a),ENSMUSG00000051984(Sec31b)" "ENSG00000138674(SEC31A),ENSG00000075826(SEC31B)" "viable,visible,short lived,gravitaxis defective" trichogen cell DRSC27091 K -0.089724587 0.189959839 -0.760778086 0.584959179 2.669818277 0.106700452 FBgn0010412 RpS19a Ribosomal protein S19a http://flybase.net/reports/FBgn0010412.html FBgn0063184 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "BcDNA:GM26647, RpS19, S19a, CG4464, ribosomal protein S19, Ribosomal protein S19, Rp S19a, S19" "IPR018277=Ribosomal protein S19e, conserved site, IPR001266=Ribosomal protein S19e" CG4464 16-Dec-15 2015_12 ENSDARG00000030602(rps19) "YOL121C(RPS19A),YNL302C(RPS19B)" WBGene00004488(rps-19) ENSXETG00000025510(RPS19) "ENSMUSG00000040952(Rps19),ENSMUSG00000072528(Gm6636),ENSMUSG00000072548(Rps19-ps2),ENSMUSG00000069391(Gm4838)" ENSG00000105372(RPS19) FBgn0025806 Rap2l Ras-associated protein 2-like http://flybase.net/reports/FBgn0025806.html "FBtr0072177, FBpp0072086" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0022008=neurogenesis, 0030718=germ-line stem cell maintenance, 0015031=protein transport, 0032486=Rap protein signal transduction" 0016020=membrane "Rap2, CG3204, O96692, Rap2L, Dm Rap21, Rap21" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR003579=Small GTPase superfamily, Rab type, IPR020849=Small GTPase superfamily, Ras type" CG3204 16-Dec-15 2015_12 "ENSDARG00000040296(rap2b),ENSDARG00000040246(LOC100003903),ENSDARG00000015649(rap2c)" WBGene00004308(rap-2) "ENSXETG00000005415(rap2c),ENSXETG00000023495(rap2a),ENSXETG00000007760(rap2b)" "ENSMUSG00000050029(Rap2c),ENSMUSG00000051615(Rap2a),ENSMUSG00000036894(Rap2b)" "ENSG00000123728(RAP2C),ENSG00000125249(RAP2A),ENSG00000181467(RAP2B)" "visible,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0033095 CG3409 http://flybase.net/reports/FBgn0033095.html protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG3409 16-Dec-15 2015_12 ENSDARG00000042807(zgc:158390) "YNL125C(ESBP6),YKL221W(MCH2)" ENSXETG00000005121(SLC16A9) ENSMUSG00000009378(Slc16a12) "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086130 Dbp21E2 DEAD box protein 21E2 http://flybase.net/reports/FBgn0086130.html "FBgn0069404, FBgn0031280" protein_coding_gene "0004386=helicase activity, 0003676=nucleic acid binding, 0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding" 0016063=rhodopsin biosynthetic process 0005737=cytoplasm "cg3561, DmRH9, CG3561, KH1" "IPR011545=DEAD/DEAH box helicase domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal" CG3561 16-Dec-15 2015_12 ENSDARG00000060411(zgc:153386) ENSXETG00000005435(DDX28) ENSMUSG00000045538(Ddx28) ENSG00000182810(DDX28) FBgn0036816 Indy I'm not dead yet http://flybase.net/reports/FBgn0036816.html "FBgn0025199, FBgn0045781, FBgn0046362" protein_coding_gene "0015141=succinate transmembrane transporter activity, 0015142=tricarboxylic acid transmembrane transporter activity, 0015137=citrate transmembrane transporter activity" "0006814=sodium ion transport, 0055085=transmembrane transport, 0010889=regulation of sequestering of triglyceride, 0008340=determination of adult lifespan" 0005886=plasma membrane "I am not dead yet, indy, anon-EST:fe3A7, BEST:LP01220, drIndy, INDY, anon-WO0172774.70, CG3979, anon-fast-evolving-3A7" "IPR001898=Sodium/sulphate symporter, IPR031312=Sodium/sulphate symporter, conserved site" CG3979 16-Dec-15 2015_12 "ENSDARG00000039999(LOC100006328),ENSDARG00000053853(slc13a2),ENSDARG00000045638(slc13a1),ENSDARG00000059053(zgc:162495)" "WBGene00003517(nac-1),WBGene00003519(nac-3)" "ENSXETG00000019731(SLC13A5),ENSXETG00000023776(slc13a2),ENSXETG00000008163(slc13a4),ENSXETG00000022751(SLC13A1),ENSXETG00000007850(SLC13A3)" "ENSMUSG00000001095(Slc13a2),ENSMUSG00000020805(Slc13a5),ENSMUSG00000018459(Slc13a3),ENSMUSG00000029700(Slc13a1),ENSMUSG00000029843(Slc13a4)" "ENSG00000007216(SLC13A2),ENSG00000141485(SLC13A5),ENSG00000081800(SLC13A1),ENSG00000158296(SLC13A3),ENSG00000164707(SLC13A4)" "lethal,recessive,viable,fertile,long lived,dominant,male fertile,female fertile,reduced,poor,lethal - all die before end of embryonic stage,partially,some die during embryonic stage" FBgn0263605 l(3)72Dn lethal (3) 72Dn http://flybase.net/reports/FBgn0263605.html "FBgn0036578, FBgn0011374, FBgn0005546" protein_coding_gene "0009267=cellular response to starvation, 0022008=neurogenesis" "CG5018, l(3)j5A4" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily, IPR011044=Quinoprotein amine dehydrogenase, beta chain-like" CG5018 16-Dec-15 2015_12 ENSDARG00000017675(cirh1a) YDR324C(UTP4) ENSXETG00000016376(cirh1a) ENSMUSG00000041438(Cirh1a) ENSG00000141076(CIRH1A) FBgn0051345 CG31345 http://flybase.net/reports/FBgn0051345.html "FBgn0038085, FBgn0038086" protein_coding_gene 0005509=calcium ion binding "0005513=detection of calcium ion, 0006909=phagocytosis" "CG14388, CG10135" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR029633=Calcyphosin-like protein" CG31345 16-Dec-15 2015_12 "ENSDARG00000003414(zgc:110369),ENSDARG00000039341" "ENSXETG00000018707(CAPSL),ENSXETG00000021881()" ENSMUSG00000039676(Capsl) ENSG00000152611(CAPSL) viable FBgn0031986 CG8673 http://flybase.net/reports/FBgn0031986.html protein_coding_gene "0008499=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" 0006486=protein glycosylation 0016020=membrane "GalT5, dbeta3GnT" "IPR002659=Glycosyl transferase, family 31" CG8673 16-Dec-15 2015_12 "ENSDARG00000042628(b3galt2),ENSDARG00000070975" "WBGene00008159(C47F8.3),WBGene00011780(T15D6.5),WBGene00008161(C47F8.5),WBGene00008785(F14B6.4),WBGene00008162(C47F8.6),WBGene00008478(E03H4.11),WBGene00008291(C54C8.3),WBGene00000267(bre-2),WBGene00008787(F14B6.6),WBGene00011665(T09F5.1),WBGene00011659(T09E11.10)" "ENSMUSG00000043300(B3galnt1),ENSMUSG00000074892(B3galt5),ENSMUSG00000034780(B3galt1),ENSMUSG00000033849(B3galt2)" "ENSG00000169255(B3GALNT1),ENSG00000183778(B3GALT5),ENSG00000172318(B3GALT1),ENSG00000162630(B3GALT2)" "partially lethal - majority die,visible" mesothoracic tergum FBgn0031003 CG7889 http://flybase.net/reports/FBgn0031003.html protein_coding_gene "IPR019410=Lysine methyltransferase, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR029426=FAM86" CG7889 16-Dec-15 2015_12 ENSDARG00000054950(fam86a) YJR129C() ENSMUSG00000022544(Fam86) "ENSG00000118894(FAM86A),ENSG00000163612,ENSG00000151539,ENSG00000214311,ENSG00000186234,ENSG00000164845" DRSC26654 K -0.377025542 -0.045296359 -0.420786741 -0.059214849 0.999802219 -1.553344791 FBgn0029648 CG3603 http://flybase.net/reports/FBgn0029648.html FBgn0062963 protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process BcDNA:RH09070 "IPR002347=Glucose/ribitol dehydrogenase, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002198=Short-chain dehydrogenase/reductase SDR" CG3603 16-Dec-15 2015_12 ENSDARG00000001169(hsd17b8) "WBGene00000988(dhs-25),WBGene00000974(dhs-11)" ENSXETG00000020365(TNeu011p10.1) ENSMUSG00000073422(H2-Ke6) "ENSG00000204228(HSD17B8),ENSG00000206216,ENSG00000112474" FBgn0033451 CG1665 http://flybase.net/reports/FBgn0033451.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0030151=molybdenum ion binding, 0003824=catalytic activity" IP19920p "IPR005303=MOSC, N-terminal beta barrel, IPR011037=Pyruvate kinase-like, insert domain, IPR005302=Molybdenum cofactor sulfurase, C-terminal" CG1665 16-Dec-15 2015_12 ENSDARG00000070487(zgc:110783) "WBGene00009049(F22B8.7),WBGene00018758(F53E10.1),WBGene00018925(F56A11.5)" "ENSXETG00000014152(),ENSXETG00000002733()" "ENSMUSG00000026621(Mosc1),ENSMUSG00000073481(Mosc2)" "ENSG00000186205(MOSC1),ENSG00000117791(MOSC2)" viable FBgn0032688 CG15160 http://flybase.net/reports/FBgn0032688.html protein_coding_gene "IPR006903=RNA polymerase II-binding domain, IPR006569=CID domain, IPR008942=ENTH/VHS" CG15160 16-Dec-15 2015_12 ENSDARG00000058089(rprd2) YDR289C(RTT103) WBGene00009451(cids-2) ENSXETG00000018652(RPRD2) ENSMUSG00000028106(Rprd2) ENSG00000163125(RPRD2) viable DRSC02461 IK -2.233957187 -0.09032007 -0.642831396 0.325038361 -0.932926621 -1.922811868 FBgn0030434 Brms1 BRMS1 ortholog http://flybase.net/reports/FBgn0030434.html protein_coding_gene "0045747=positive regulation of Notch signaling pathway, 0045893=positive regulation of transcription, DNA-templated" 0070822=Sin3-type complex "CG4400, BRMS1L, dBrms1" IPR013907=Sds3-like CG4400 16-Dec-15 2015_12 "ENSDARG00000051955(brms1),ENSDARG00000006235(brms1l),ENSDARG00000018047(LOC562889)" "ENSXETG00000020567(BRMS1),ENSXETG00000002912(brms1l)" "ENSMUSG00000012076(Brms1l),ENSMUSG00000080268(Brms1)" "ENSG00000100916(BRMS1L),ENSG00000174744(BRMS1)" "viable,fertile,lethal - all die before end of prepupal stage,recessive,some die during first instar larval stage,some die during second instar larval stage,majority die during third instar larval stage,some die during prepupal stage,some die during third instar larval stage,developmental rate defective,visible,partially lethal - majority die,some die during pupal stage" "eye-antennal disc,wing disc,trichogen cell" DRSC19896 K -1.39615309 0.951794383 0.338262235 0.74032614 1.88591217 1.993852351 FBgn0051624 CG31624 http://flybase.net/reports/FBgn0051624.html FBgn0032932 protein_coding_gene 0008270=zinc ion binding "Tes88, CG17401" "IPR001781=Zinc finger, LIM-type" CG31624 16-Dec-15 2015_12 WBGene00012379(Y1A5A.1) "ENSXETG00000022912(fhl3),ENSXETG00000002577(FHL2),ENSXETG00000001065(FHL5),ENSXETG00000019760(fhl1)" "ENSMUSG00000032643(Fhl3),ENSMUSG00000008136(Fhl2),ENSMUSG00000028259(Fhl5),ENSMUSG00000050035(Fhl4),ENSMUSG00000023092(Fhl1)" "ENSG00000183386(FHL3),ENSG00000115641(FHL2),ENSG00000112214(FHL5),ENSG00000022267(FHL1)" FBgn0026268 antdh antdh http://flybase.net/reports/FBgn0026268.html protein_coding_gene "0004090=carbonyl reductase (NADPH) activity, 0016491=oxidoreductase activity" "0055114=oxidation-reduction process, 0008152=metabolic process, 0007608=sensory perception of smell" 0005737=cytoplasm "FOHSDR, CG1386, Antdh, AntDH" "IPR002347=Glucose/ribitol dehydrogenase, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG1386 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) adult stage antennal segment 3

viable FBgn0036770 Prestin Prestin http://flybase.net/reports/FBgn0036770.html protein_coding_gene "0015499=formate transmembrane transporter activity, 0015085=calcium ion transmembrane transporter activity, 0015381=high-affinity sulfate transmembrane transporter activity, 0015106=bicarbonate transmembrane transporter activity, 0005452=inorganic anion exchanger activity, 0019531=oxalate transmembrane transporter activity, 0015116=sulfate transmembrane transporter activity" "0070588=calcium ion transmembrane transport, 0019532=oxalate transport, 0008272=sulfate transport, 0015724=formate transport, 0015701=bicarbonate transport" 0016021=integral component of membrane "CG5485, Slc26a5, dpres, dPrestin" "IPR002645=STAS domain, IPR011547=SLC26A/SulP transporter domain, IPR001902=SLC26A/SulP transporter" CG5485 16-Dec-15 2015_12 "ENSDARG00000054127(slc26a6l),ENSDARG00000058738(LOC557779),ENSDARG00000055835(LOC100005108),ENSDARG00000071221,ENSDARG00000022424(slc26a5),ENSDARG00000003615(si:dkey-31f5.1),ENSDARG00000069431(slc26a4),ENSDARG00000029832(slc26a1),ENSDARG00000011618(LOC557046),ENSDARG00000007371(slc26a3)" "WBGene00013963(sulp-8),WBGene00012259(sulp-7),WBGene00010788(sulp-4),WBGene00010789(sulp-5)" "ENSXETG00000023111(SLC26A5),ENSXETG00000016188(),ENSXETG00000024748(),ENSXETG00000012196(),ENSXETG00000025660(),ENSXETG00000022019(),ENSXETG00000012233(),ENSXETG00000005927(),ENSXETG00000005947(),ENSXETG00000020492(SLC26A2),ENSXETG00000018033(SLC26A1),ENSXETG00000006224(SLC26A10)" "ENSMUSG00000023259(Slc26a6),ENSMUSG00000029015(Slc26a5),ENSMUSG00000020651(Slc26a4),ENSMUSG00000001225(Slc26a3),ENSMUSG00000042268(Slc26a9)" "ENSG00000170615(SLC26A5),ENSG00000091137(SLC26A4),ENSG00000091138(SLC26A3),ENSG00000174502(SLC26A9),ENSG00000155850(SLC26A2),ENSG00000145217(SLC26A1)" viable DRSC10507 EK -0.154824763 0.28172203 0.420070644 1.500822397 1.601242355 1.825557739 FBgn0064123 stg1 stargazin-like protein http://flybase.net/reports/FBgn0064123.html "FBgn0031154, FBgn0031156, FBgn0031158, FBgn0052514, FBgn0053670" protein_coding_gene 0016247=channel regulator activity "2000311=regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, 0051966=regulation of synaptic transmission, glutamatergic" 0016021=integral component of membrane "CG11568, CG33670, CG32514-ORFA, Stg1, Dro STG1, CG11569, CG32514, STG1, CG10985" IPR004031=PMP-22/EMP/MP20/Claudin superfamily CG33670 16-Dec-15 2015_12 "ENSDARG00000058460(LOC567438),ENSDARG00000032565(cacng2a),ENSDARG00000020450(zgc:112144),ENSDARG00000070626,ENSDARG00000009621,ENSDARG00000039238(LOC797554)" "viable,fertile" FBgn0266720 Snap24 Synaptosomal-associated protein 24kDa http://flybase.net/reports/FBgn0266720.html "FBgn0028401, FBgn0037745, FBgn0044818" protein_coding_gene "0005484=SNAP receptor activity, 0019905=syntaxin binding" "0061025=membrane fusion, 0006893=Golgi to plasma membrane transport, 0016192=vesicle-mediated transport, 0007269=neurotransmitter secretion" "0030667=secretory granule membrane, 0005886=plasma membrane, 0031201=SNARE complex, 0030141=secretory granule" "Synapse protein 24, CG9474, SNAP-24, SNAP24, SNAP-25b, Snap25b" "IPR000727=Target SNARE coiled-coil homology domain, IPR000928=SNAP-25" CG9474 16-Dec-15 2015_12 "ENSDARG00000020609(snap25a),ENSDARG00000040965(zgc:101731),ENSDARG00000058117(snap25b)" WBGene00004364(ric-4) ENSXETG00000015096(snap25) ENSMUSG00000027273(Snap25) ENSG00000132639(SNAP25) FBgn0036239 Pop2 Pop2 http://flybase.net/reports/FBgn0036239.html protein_coding_gene "0005515=protein binding, 0003676=nucleic acid binding, 0004535=poly(A)-specific ribonuclease activity" "0048666=neuron development, 0017148=negative regulation of translation, 0022008=neurogenesis, 0007095=mitotic G2 DNA damage checkpoint, 0007517=muscle organ development, 0006357=regulation of transcription from RNA polymerase II promoter, 0006402=mRNA catabolic process, 0000289=nuclear-transcribed mRNA poly(A) tail shortening" "0005737=cytoplasm, 0005829=cytosol, 0030014=CCR4-NOT complex, 0005634=nucleus" "pop2, CG5684, Caf1, CAF1, POP2" "IPR012337=Ribonuclease H-like domain, IPR006941=Ribonuclease CAF1" CG5684 16-Dec-15 2015_12 "ENSDARG00000020043(cnot8),ENSDARG00000032116(cnot7)" YNR052C(POP2) WBGene00000369(ccf-1) "ENSXETG00000008409(cnot8),ENSXETG00000000701(CNOT7)" "ENSMUSG00000031601(Cnot7),ENSMUSG00000020515(Cnot8)" "ENSG00000198791(CNOT7),ENSG00000155508(CNOT8)" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC10537 IEK -0.006786555 -2.665054549 -4.264750873 -4.157301268 1.238205636 1.773006069 FBgn0035519 CG1309 http://flybase.net/reports/FBgn0035519.html protein_coding_gene 0012505=endomembrane system "IPR029058=Alpha/Beta hydrolase fold, IPR029059=Alpha/beta hydrolase fold-5" CG1309 16-Dec-15 2015_12 WBGene00018131(F37A4.1) ENSXETG00000024070(bat5) "ENSMUSG00000007036(Bat5),ENSMUSG00000055882(BC050777)" "ENSG00000096467,ENSG00000204427(ABHD16A),ENSG00000206403,ENSG00000183260(ABHD16B)" viable FBgn0029831 CG5966 http://flybase.net/reports/FBgn0029831.html protein_coding_gene "0016298=lipase activity, 0052689=carboxylic ester hydrolase activity" "0007476=imaginal disc-derived wing morphogenesis, 0016042=lipid catabolic process" "141233_at, triglyceride lipase" "IPR013818=Lipase, N-terminal, IPR016272=Lipase, LIPH-type, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family" CG5966 16-Dec-15 2015_12 "ENSDARG00000069924,ENSDARG00000071472,ENSDARG00000067749,ENSDARG00000058466,ENSDARG00000034667(LOC100331214),ENSDARG00000031044(lipg),ENSDARG00000053476(lipc),ENSDARG00000005332(LOC100003046),ENSDARG00000007108(zgc:91985),ENSDARG00000070418" "ENSXETG00000004181(pnlip),ENSXETG00000000930(),ENSXETG00000000927(Q642T5_XENTR),ENSXETG00000000936(),ENSXETG00000000940(),ENSXETG00000014314(PNLIPRP3)" "ENSMUSG00000046008(Pnlip),ENSMUSG00000025091(Pnliprp2),ENSMUSG00000042179(Pnliprp1)" "ENSG00000175535(PNLIP),ENSG00000187021(PNLIPRP1),ENSG00000165862(PNLIPRP2),ENSG00000203837(PNLIPRP3)" viable FBgn0261606 RpL27A Ribosomal protein L27A http://flybase.net/reports/FBgn0261606.html "FBgn0010410, FBgn0019937, FBgn0025298, FBgn0002595, FBgn0001910" protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0000022=mitotic spindle elongation, 0051298=centrosome duplication" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "l(2)24EFh, CG15442, M(2)24F-1, Mz, M(2)z, RpL27Ab, ribosomal protein L27a, M(2)Z, l(2)24Fb, M(2L)z, Rp L27A, Minute, RpL27a2, M[[z]], anon-EST:Posey257, Minute (2) 24F, RpL27Aa, M(2)24F, M, RpL27a, rpL27a" "IPR030878=Ribosomal protein L15, IPR021131=Ribosomal protein L18e/L15P, IPR001196=Ribosomal protein L15, conserved site" CG15442 16-Dec-15 2015_12 YGL103W(RPL28) WBGene00021350(Y37E3.8) ENSXETG00000003912(RPL27A) "ENSMUSG00000046364(Rpl27a),ENSMUSG00000057036(Gm7536),ENSMUSG00000062461(Gm5453),ENSMUSG00000065950(Gm5908),ENSMUSG00000061488(Rpl27a-ps1),ENSMUSG00000062962(Gm6378),ENSMUSG00000058430(Rpl27a-ps2)" ENSG00000166441(RPL27A) " adult stage , embryonic stage && larval stage && adult stage " " adult head

, organism

" DRSC00781 IEK -1.440376425 -2.156419647 0.436583058 -5.317921167 0.514185084 2.521196621 FBgn0032505 CG16826 http://flybase.net/reports/FBgn0032505.html protein_coding_gene CG16826 16-Dec-15 2015_12 viable FBgn0020272 mst misato http://flybase.net/reports/FBgn0020272.html FBgn0001566 protein_coding_gene 0003924=GTPase activity "0000070=mitotic sister chromatid segregation, 0090307=mitotic spindle assembly" "0005856=cytoskeleton, 0005737=cytoplasm" "lethal(1)19Fg, l(1)19Fg, LB-20, l(1)LB20, l(1)LB14, CG1424, lLB14, unnamed, LB20" "IPR029209=DML1/Misato, tubulin domain, IPR019605=Misato Segment II tubulin-like domain, IPR003008=Tubulin/FtsZ, GTPase domain" CG1424 16-Dec-15 2015_12 ENSDARG00000024381(msto1) YMR211W(DML1) ENSXETG00000021439(MSTO1) ENSMUSG00000068922(Msto1) ENSG00000125459(MSTO1) " larval stage , embryonic stage -- adult stage , adult stage | female , adult stage , pupal stage | late , adult stage && oogenesis stage " " embryonic/larval fat body

, imaginal disc

, adult brain

, brain

, ovary

" "viable,fertile,lethal,recessive,cell lethal,germline clone,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,wild-type" mitotic spindle FBgn0029868 ND-B16.6 NADH dehydrogenase (ubiquinone) B16.6 subunit http://flybase.net/reports/FBgn0029868.html protein_coding_gene 0003954=NADH dehydrogenase activity "0006120=mitochondrial electron transport, NADH to ubiquinone" 0005747=mitochondrial respiratory chain complex I "NADH ubiquinone oxidoreductase B16.6, NADH:ubiquinone oxidoreductase B16.6 subunit, CG3446, NB6M, NADH-ubiquinone oxidoreductase B16.6 subunit" IPR009346=GRIM-19 CG3446 16-Dec-15 2015_12 WBGene00016393(C34B2.8) ENSXETG00000018373(Q6PBF2_XENTR) ENSMUSG00000036199(Ndufa13) ENSG00000130288 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC26200 K -0.569773858 0.406801043 0.155061306 -0.151319083 0.056470529 -1.63279106 FBgn0044088 E(rst)E146 E(rst)E146 http://flybase.net/reports/FBgn0044088.html gene 0001745=compound eye morphogenesis E146 16-Dec-15 2015_12 viable FBgn0035162 CG13900 http://flybase.net/reports/FBgn0035162.html protein_coding_gene 0003684=damaged DNA binding "0007052=mitotic spindle organization, 0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0030532=small nuclear ribonucleoprotein complex, 0071013=catalytic step 2 spliceosome, 0005686=U2 snRNP" "SF3B3, splicing factor 3b subunit 3, putative damaged DNA-binding activity" "IPR004871=Cleavage/polyadenylation specificity factor, A subunit, C-terminal, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG13900 16-Dec-15 2015_12 ENSDARG00000003969(sf3b3) YML049C(RSE1) WBGene00019323(teg-4) ENSMUSG00000033732(Sf3b3) ENSG00000189091(SF3B3) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08370 I -0.080701333 1.99189753 0.522481965 0.911042779 -1.439788591 -0.749702092 FBgn0014133 bif bifocal http://flybase.net/reports/FBgn0014133.html protein_coding_gene "0008157=protein phosphatase 1 binding, 0051015=actin filament binding, 0008017=microtubule binding, 0003779=actin binding" "0007476=imaginal disc-derived wing morphogenesis, 0016321=female meiosis chromosome segregation, 0030517=negative regulation of axon extension, 0007411=axon guidance" 0005737=cytoplasm "CG1822, Bifocal" CG1822 16-Dec-15 2015_12 adult stage adult head

" embryonic stage | late , embryonic stage | stage >=16 , embryonic stage | stage >=14 , embryonic stage | early , embryonic stage | stage 13-17 , larval stage | third instar , pupal stage " " embryonic central nervous system

, longitudinal connective

, posterior commissure

, anterior commissure

, neuron

, morphogenetic furrow | posterior to

, photoreceptor cell R1--8

, rhabdomere

" "viable,fertile,neuroanatomy defective,meiotic cell cycle defective,dominant,visible,recessive" "macrochaeta,photoreceptor cell R2 & axon[-],photoreceptor cell R3 & axon[-],photoreceptor cell R4 & axon[-],photoreceptor cell R5 & axon[-],eye,rhabdomere,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,lamina anlage glial cell,photoreceptor cell R1 & axon,photoreceptor cell R6 & axon,photoreceptor cell R7 & axon,photoreceptor cell R8 & axon,lamina,interommatidial bristle,supernumerary,ommatidium,actin filament,embryonic/larval optic neuropil,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF,photoreceptor cell R6 & axonGMR.PF,lamina plexus,medulla,photoreceptor cell,photoreceptor cell R7 & axonsev.PM181" FBgn0035113 pyx pyrexia http://flybase.net/reports/FBgn0035113.html protein_coding_gene "0005262=calcium channel activity, 0005261=cation channel activity" "0009408=response to heat, 0051290=protein heterotetramerization, 0034220=ion transmembrane transport, 0006812=cation transport, 0048060=negative gravitaxis, 0006816=calcium ion transport" "0034703=cation channel complex, 0016021=integral component of membrane" "trpA2, Pyrexia, CG17142, dTRPA2, CT33412, Pyx" "IPR005821=Ion transport domain, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR030288=Transient receptor potential ankyrin 1 channel" CG17142 16-Dec-15 2015_12 "viable,gravitaxis defective,paralytic,heat sensitive,thermotaxis behavior defective,neurophysiology defective" DRSC08510 K 0.428476799 0.367704321 0.231284726 0.135431481 -1.596038983 -0.271680622 FBgn0021814 Vps28 Vacuolar protein sorting 28 http://flybase.net/reports/FBgn0021814.html FBgn0033254 protein_coding_gene 0005515=protein binding "0010796=regulation of multivesicular body size, 0007291=sperm individualization, 0006914=autophagy, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0007293=germarium-derived egg chamber formation, 0032509=endosome transport via multivesicular body sorting pathway, 0060429=epithelium development, 0030713=ovarian follicle cell stalk formation, 0044130=negative regulation of growth of symbiont in host, 0048749=compound eye development, 0008593=regulation of Notch signaling pathway, 0030036=actin cytoskeleton organization, 0000046=autophagic vacuole fusion, 0009792=embryo development ending in birth or egg hatching, 0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway" 0000813=ESCRT I complex "ESCRT-I, dvps28, Dvps28, dVps28, DmVps28, ESCRT-II, l(2)k16503, CG12770, Vps28, vps28" "IPR017898=Vacuolar protein sorting-associated, VPS28, N-terminal, IPR017899=Vacuolar protein sorting-associated, VPS28, C-terminal, IPR007143=Vacuolar protein sorting-associated, VPS28" CG12770 16-Dec-15 2015_12 ENSDARG00000045949(vps28) YPL065W(VPS28) WBGene00013598(vps-28) ENSXETG00000004029(vps28) ENSMUSG00000062381(Vps28) ENSG00000160948(VPS28) "lethal,recessive,cell shape defective,germline clone,male sterile,tumorigenic" "ommatidium,somatic clone,eye photoreceptor cell,actin cytoskeleton | embryonic stage | germline clone,pole cell,germline clone,nucleus | embryonic stage | germline clone,autophagic vacuole | conditional | somatic clone,fat body,conditional,spermatid,spermatozoon,eye,egg chamber,plasma membrane | somatic clone,actin filament | somatic clone,embryonic/larval digestive system,epithelium,interfollicle cell,female germline cyst" FBgn0040190 l(1)G0197 lethal (1) G0197 http://flybase.net/reports/FBgn0040190.html gene 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0029932 CG4607 http://flybase.net/reports/FBgn0029932.html protein_coding_gene 0022891=substrate-specific transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR003663=Sugar/inositol transporter, IPR005828=Major facilitator, sugar transporter-like" CG4607 16-Dec-15 2015_12 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0002329 l(3)87Aa lethal (3) 87Aa http://flybase.net/reports/FBgn0002329.html gene "l(3)ck8, ck8" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,some die during larval stage" FBgn0053822 His1:CG33822 His1:CG33822 http://flybase.net/reports/FBgn0053822.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33822 "IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain" CG33822 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0035078 Tpc2 Thiamine pyrophosphate carrier protein 2 http://flybase.net/reports/FBgn0035078.html protein_coding_gene "0015619=thiamine pyrophosphate-transporting ATPase activity, 0022857=transmembrane transporter activity, 0017077=oxidative phosphorylation uncoupler activity" "0055085=transmembrane transport, 0030974=thiamine pyrophosphate transport, 0006839=mitochondrial transport" 0031966=mitochondrial membrane "DmTpc2, thiamine pyrophosphate carrier protein, CG2857" "IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain, IPR018108=Mitochondrial substrate/solute carrier" CG2857 16-Dec-15 2015_12 ENSDARG00000038942 WBGene00016588(C42C1.10) ENSMUSG00000020744(Slc25a19) ENSG00000125454(SLC25A19) viable FBgn0039617 DIP-ë_ Dpr-interacting protein ë_ http://flybase.net/reports/FBgn0039617.html FBgn0044679 protein_coding_gene "DIP-gamma, CG14521, anon-WO0140519.196, CT34248, 14521" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG14521 16-Dec-15 2015_12 "ENSDARG00000013005(zgc:92901),ENSDARG00000022176(zgc:110372),ENSDARG00000018065(ntm),ENSDARG00000021607(negr1)" WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" FBgn0061362 CG33785 http://flybase.net/reports/FBgn0061362.html "FBgn0034536, FBgn0050144, FBgn0053005, FBgn0053785, FBtr0086250, FBpp0085562, FBtr0086251" protein_coding_gene "0008270=zinc ion binding, 0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" 0006359=regulation of transcription from RNA polymerase III promoter 0005666=DNA-directed RNA polymerase III complex "CG30144, Dromel_CG33786_FBtr0091786_uORF, CG33005ORFA, CG33005, CG10438a, CG33005-ORFA, CG10438" "IPR001222=Zinc finger, TFIIS-type, IPR001529=DNA-directed RNA polymerase, M/15kDa subunit, IPR012164=DNA-directed RNA polymerase, subunit C11/M/9, IPR019761=DNA-directed RNA polymerase M, 15kDa subunit, conserved site" CG33785 16-Dec-15 2015_12 ENSDARG00000037835(polr3k) YDR045C(RPC11) WBGene00022309(Y77E11A.6) ENSXETG00000001142(polr3k) ENSMUSG00000038628(Polr3k) ENSG00000161980(POLR3K) FBgn0035236 CG12004 http://flybase.net/reports/FBgn0035236.html FBgn0025198 protein_coding_gene 0030246=carbohydrate binding "0008039=synaptic target recognition, 0050832=defense response to fungus" "anon-EST:fe3A8, anon-fast-evolving-3A8" IPR005178=Organic solute transporter subunit alpha/Transmembrane protein 184 CG12004 16-Dec-15 2015_12 "ENSDARG00000045147(zgc:112178),ENSDARG00000032559,ENSDARG00000039043,ENSDARG00000037857(tmem184a)" YKR051W() WBGene00009574(F40E10.6) "ENSXETG00000018120(TEgg081o18.1),ENSXETG00000006356(TEgg137e04.1)" "ENSMUSG00000009035(Tmem184b),ENSMUSG00000036687(Tmem184a)" "ENSG00000198792(TMEM184B),ENSG00000215155" "immune response defective,viable,fertile" "hemocyte,plasmatocyte" DRSC08215 E 1.330203109 0.536979834 1.850553401 -0.250129487 -1.205167277 -0.471144664 FBgn0037339 Pi4KIIë± Pi4KIIë± http://flybase.net/reports/FBgn0037339.html protein_coding_gene 0004430=1-phosphatidylinositol 4-kinase activity "0046854=phosphatidylinositol phosphorylation, 0007032=endosome organization, 0032252=secretory granule localization, 0033365=protein localization to organelle, 0007030=Golgi organization, 0033363=secretory granule organization" "0005886=plasma membrane, 0005802=trans-Golgi network, 0031902=late endosome membrane" "CG2929, PI4KIIbeta, Pi4KIIa, Pi4KIIalpha, PI4KIIalpha, PI4KII" "IPR000403=Phosphatidylinositol 3-/4-kinase, catalytic domain" CG2929 16-Dec-15 2015_12 "ENSDARG00000033666(pi4k2a),ENSDARG00000013881(pi4k2b)" YJL100W(LSB6) WBGene00022501(ZC8.6) "ENSXETG00000000962(pi4k2b),ENSXETG00000013516(pi4k2)" ENSMUSG00000029186(Pi4k2b) "ENSG00000043822,ENSG00000038210(PI4K2B)" "viable,fertile" "rhabdomereGMR.PF,Golgi apparatus" FBgn0030743 CG9921 http://flybase.net/reports/FBgn0030743.html protein_coding_gene "IPR007667=Hypoxia induced protein, domain" CG9921 16-Dec-15 2015_12 ENSDARG00000052371(zgc:112385) WBGene00011859(T20D3.6) ENSXETG00000027971() ENSMUSG00000025868(Higd2a) "ENSG00000146066(HIGD2A),ENSG00000175202" viable DRSC20220 K -0.394071829 0.91068287 -1.137003757 0.663211691 1.181299115 -1.706965137 FBgn0051729 CG31729 http://flybase.net/reports/FBgn0051729.html "FBgn0032500, FBgn0032501" protein_coding_gene "0000287=magnesium ion binding, 0004012=phospholipid-translocating ATPase activity, 0005524=ATP binding" 0045332=phospholipid translocation 0016021=integral component of membrane "CG16823, DmCG31729, CG6263" "IPR023214=HAD-like domain, IPR018303=P-type ATPase, phosphorylation site, IPR008250=P-type ATPase, A domain, IPR023299=P-type ATPase, cytoplasmic domain N, IPR006539=P-type ATPase, subfamily IV, IPR001757=P-type ATPase" CG31729 16-Dec-15 2015_12 ENSDARG00000062521(atp9b) YIL048W(NEO1) "WBGene00009498(tat-5),WBGene00017174(tat-6)" "ENSXETG00000000852(ATP9B),ENSXETG00000012313(atp9a)" "ENSMUSG00000024566(Atp9b),ENSMUSG00000027546(Atp9a)" "ENSG00000166377(ATP9B),ENSG00000054793(ATP9A)" viable FBgn0032171 CG5846 http://flybase.net/reports/FBgn0032171.html protein_coding_gene "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG5846 16-Dec-15 2015_12 "ENSDARG00000016730(rfxank),ENSDARG00000035399(ankra2)" "ENSXETG00000016820(ankra2),ENSXETG00000013042(RFXANK)" "ENSMUSG00000036120(Rfxank),ENSMUSG00000021661(Ankra2)" "ENSG00000064490(RFXANK),ENSG00000164331(ANKRA2)" "viable,body color defective" mesothoracic tergum FBgn0020258 ppk pickpocket http://flybase.net/reports/FBgn0020258.html protein_coding_gene "0044736=acid-sensing ion channel activity, 0005272=sodium channel activity" "0008345=larval locomotory behavior, 2000252=negative regulation of feeding behavior, 0048266=behavioral response to pain, 0040040=thermosensory behavior, 0006814=sodium ion transport, 0007638=mechanosensory behavior, 0050966=detection of mechanical stimulus involved in sensory perception of pain" 0016021=integral component of membrane "BG:DS06238.1, CG3478, PPK1, mdNaC1, dmdNaCl, Drifter, multidendritic neurons sodium channel 1, pickpocket 1, pkt, ppk1, Pickpocket1, unnamed, PPK, pickpocket1, dmdNaC1" "IPR020903=Na+ channel, amiloride-sensitive, conserved site, IPR001873=Na+ channel, amiloride-sensitive" CG3478 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" "WBGene00003174(mec-10),WBGene00003168(mec-4),WBGene00000950(deg-1),WBGene00012137(asic-2)" "ENSXETG00000001026(),ENSXETG00000018954(scnn1a)" ENSMUSG00000030340(Scnn1a) "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" " embryonic stage | stage 17 , larval stage | early , embryonic stage , embryonic stage -- adult stage , larval stage , adult stage " " embryonic peripheral nervous system | restricted

, multidendritic neuron | subset

, peripheral nervous system | restricted

, dendritic arborising neuron | subset

" " embryonic stage | stage 17 , larval stage | early " " multidendritic neuron | subset

, peripheral nervous system | restricted

, dendritic arborising neuron | subset

" "locomotor behavior defective,pain response defective,neurophysiology defective,behavior defective,small body,large body,touch sensitivity defective" class IV dendritic arborizing neuron FBgn0032397 Tom70 Translocase of outer membrane 70 http://flybase.net/reports/FBgn0032397.html protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0006626=protein targeting to mitochondrion 0005742=mitochondrial outer membrane translocase complex "RE66761p, dtom70, CG6756" "IPR019734=Tetratricopeptide repeat, IPR013105=Tetratricopeptide repeat 2, IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG6756 16-Dec-15 2015_12 ENSDARG00000029639(tomm70a) "YHR117W(TOM71),YNL121C(TOM70)" ENSXETG00000011867(TOMM70A) ENSMUSG00000022752(Tomm70a) ENSG00000154174(TOMM70A) "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033912 RpS23 Ribosomal protein S23 http://flybase.net/reports/FBgn0033912.html "FBgn0026271, FBgn0026280" protein_coding_gene 0003735=structural constituent of ribosome "0051297=centrosome organization, 0006412=translation, 0051298=centrosome duplication" "0022627=cytosolic small ribosomal subunit, 0005840=ribosome, 0005829=cytosol" "anon-EST:Posey63, anon-EST:Posey158, CT24703, CG8415, ribosomal protein S23, RPS23, Rp S23" "IPR006032=Ribosomal protein S12/S23, IPR012340=Nucleic acid-binding, OB-fold, IPR005680=Ribosomal protein S23, eukaryotic/archaeal" CG8415 16-Dec-15 2015_12 ENSDARG00000021838(zgc:171710) "YPR132W(RPS23B),YGR118W(RPS23A)" WBGene00004492(rps-23) ENSXETG00000027811(rps23) "ENSMUSG00000049517(Rps23),ENSMUSG00000073559(Gm8618)" ENSG00000186468(RPS23) lethal DRSC07169 IEK -0.260748326 -1.527367747 0.563429869 -3.766780465 2.069063174 2.22837979 FBgn0039229 Saf-B Scaffold attachment factor B http://flybase.net/reports/FBgn0039229.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003676=nucleic acid binding" "0000381=regulation of alternative mRNA splicing, via spliceosome" "0005634=nucleus, 0005654=nucleoplasm, 0016363=nuclear matrix" "cg6995, LD22822, saf-b, CG6995, SAF-B" "IPR003034=SAP domain, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG6995 16-Dec-15 2015_12 "ENSDARG00000020467(safb),ENSDARG00000017150" WBGene00009314(F32B4.4) ENSXETG00000010840(SLTM) "ENSMUSG00000032212(Sltm),ENSMUSG00000071054(Safb),ENSMUSG00000042625(Safb2)" "ENSG00000137776(SLTM),ENSG00000130254(SAFB2),ENSG00000160633(SAFB)" DRSC16167 IE 2.744801637 3.325299303 2.302410154 0.789484686 -0.0043265 0.448012631 FBgn0266019 rudhira rudhira http://flybase.net/reports/FBgn0266019.html "FBgn0067660, FBgn0262684, FBgn0052663, FBgn0030337, FBgn0052662, FBgn0025954" protein_coding_gene 0044351=macropinocytosis "0005829=cytosol, 0005737=cytoplasm" "DRudh, Rudh, clone 2.41, CG43154, CG32663, CG32662, anon-EST:Liang-2.41, CG1905, Drudh" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR022175=Breast carcinoma amplified sequence 3" CG43154 16-Dec-15 2015_12 ENSDARG00000054893(bcas3) WBGene00018953(F56C9.10) ENSXETG00000020553(BCAS3) ENSMUSG00000059439(Bcas3) ENSG00000141376(BCAS3) FBgn0031871 Fgop2 Fibroblast growth factor receptor 1 oncogene partner 2 http://flybase.net/reports/FBgn0031871.html protein_coding_gene "0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction" "Fibroblast growth factor receptor 1 oncogene partner 2 ortholog, FGOP2, fibroblast growth factor receptor 1 oncogene partner 2, CG10158, FGFR1OP2" IPR008555=Suppressor of IKBKE 1 CG10158 16-Dec-15 2015_12 "ENSDARG00000009657(fgfr1op2),ENSDARG00000060981(LOC568173)" "ENSXETG00000016502(fgfr1op2),ENSXETG00000021446(BC088764.1)" "ENSMUSG00000040242(Fgfr1op2),ENSMUSG00000027854(Sike1)" "ENSG00000111790(FGFR1OP2),ENSG00000052723(SIKE1)" "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" FBgn0065932 l(2)SH0133 lethal (2) SH0133 http://flybase.net/reports/FBgn0065932.html gene l(2)SH2 0133 16-Dec-15 2015_12 "lethal,recessive" FBgn0266162 CR44868 http://flybase.net/reports/FBgn0266162.html non_protein_coding_gene CR44868 16-Dec-15 2015_12 FBgn0266922 d::Zyx http://flybase.net/reports/FBgn0266922.html engineered_fusion_gene Zyx:Dachs 16-Dec-15 2015_12 cell polarity defective "wing,wing hair" FBgn0031975 Tg Transglutaminase http://flybase.net/reports/FBgn0031975.html protein_coding_gene 0003810=protein-glutamine gamma-glutamyltransferase activity "0045087=innate immune response, 0018149=peptide cross-linking, 0042381=hemolymph coagulation" "dTG, CG7356, Transglutaminase, Tg, TG" "IPR014756=Immunoglobulin E-set, IPR013783=Immunoglobulin-like fold, IPR001102=Transglutaminase, N-terminal, IPR008958=Transglutaminase, C-terminal, IPR002931=Transglutaminase-like, IPR023608=Protein-glutamine gamma-glutamyltransferase, eukaryota" CG7356 16-Dec-15 2015_12 "ENSDARG00000017799(LOC100334173),ENSDARG00000012130(si:ch211-9d9.3),ENSDARG00000070226,ENSDARG00000005913,ENSDARG00000044084,ENSDARG00000019024(LOC793096),ENSDARG00000036893(f13a1)" ENSXETG00000014626(TGM1) "ENSMUSG00000022218(Tgm1),ENSMUSG00000039109(F13a1)" "ENSG00000092295(TGM1),ENSG00000124491(F13A1)" "visible,short lived,partially lethal - majority die,some die during pupal stage,viable" "eye,crossvein,wing,tergite,ommatidium,interommatidial bristle" DRSC29048 K 0.418224094 -0.501149341 -0.235865979 -0.03854332 2.008931023 -0.763295694 FBgn0019982 Gs1l GS1-like http://flybase.net/reports/FBgn0019982.html protein_coding_gene 0016787=hydrolase activity "0008152=metabolic process, 0042060=wound healing" "CG15441, GS1-like, gs1-like, GS1l, GS1-like protein, 19864674, GS1like" "IPR006439=HAD hydrolase, subfamily IA, IPR023214=HAD-like domain" CG15441 16-Dec-15 2015_12 ENSDARG00000027826(hdhd1a) YKL033W-A() WBGene00020113(R151.10) ENSXETG00000008168(hdhd1a1) ENSMUSG00000048875(Hdhd1a) ENSG00000130021(HDHD1) adult stage viable FBgn0038331 Ccm3 Cerebral cavernous malformation 3 ortholog http://flybase.net/reports/FBgn0038331.html protein_coding_gene 0060439=trachea morphogenesis "CG5073, Cerebral cavernous malformation 3" IPR009652=Protein of unknown function DUF1241 CG5073 16-Dec-15 2015_12 "ENSDARG00000012591(pdcd10b),ENSDARG00000035054(pdcd10a)" WBGene00007561(C14A4.11) ENSXETG00000022875(pdcp10) ENSMUSG00000027835(Pdcd10) ENSG00000114209(PDCD10) "viable,lethal" terminal tracheal cell | third instar larval stage FBgn0053337 CG33337 http://flybase.net/reports/FBgn0053337.html protein_coding_gene "0016746=transferase activity, transferring acyl groups, 0016747=transferase activity, transferring acyl groups other than amino-acyl groups" unnamed "IPR002656=Acyltransferase 3, IPR006621=Nose resistant-to-fluoxetine protein, N-terminal" CG33337 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" FBgn0034908 CG5543 http://flybase.net/reports/FBgn0034908.html FBgn0062187 protein_coding_gene 0022008=neurogenesis anon-WO0118547.181 "IPR001680=WD40 repeat, IPR019775=WD40 repeat, conserved site, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG5543 16-Dec-15 2015_12 WBGene00001513(gad-1) ENSXETG00000004784(WDR70) ENSMUSG00000039828(Wdr70) ENSG00000082068(WDR70) "lethal,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032853 CG10651 http://flybase.net/reports/FBgn0032853.html protein_coding_gene 0032504=multicellular organism reproduction "0005576=extracellular region, 0005615=extracellular space" 38C.2 "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG10651 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" FBgn0033015 d4 d4 http://flybase.net/reports/FBgn0033015.html FBan0002682 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding" "0007517=muscle organ development, 0006355=regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis" 0005634=nucleus "CG2682, Dd4, dd4, D4" "IPR001965=Zinc finger, PHD-type, IPR025750=Requiem/DPF N-terminal domain, IPR001841=Zinc finger, RING-type, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG2682 16-Dec-15 2015_12 "ENSDARG00000012219(dpf2),ENSDARG00000037291(dpf2l),ENSDARG00000025309(dpf3),ENSDARG00000053548(dpf1)" WBGene00016200(C28H8.9) "ENSXETG00000001672(dpf2),ENSXETG00000021846(DPF3)" "ENSMUSG00000021221(Dpf3),ENSMUSG00000030584(Dpf1),ENSMUSG00000024826(Dpf2)" "ENSG00000011332(DPF1),ENSG00000133884(DPF2)" "partially lethal - majority die,some die during pupal stage" FBgn0003023 otu ovarian tumor http://flybase.net/reports/FBgn0003023.html protein_coding_gene 0004843=ubiquitin-specific protease activity "0048477=oogenesis, 0007281=germ cell development, 0018992=germ-line sex determination, 0048134=germ-line cyst formation, 0016579=protein deubiquitination, 0019099=female germ-line sex determination, 0051276=chromosome organization, 0032877=positive regulation of DNA endoreduplication" 0005737=cytoplasm "Ovarian tumour, fs(1)jA265, OTU, K, DROOTUA, CG12743, Ovarian tumor, Otu, fs(1)23l, fs(1)M101, fs(1)otu, fs(1)231, unnamed" "IPR002999=Tudor domain, IPR003323=OTU domain" CG12743 16-Dec-15 2015_12 ENSDARG00000054374(otul) ENSMUSG00000041718 ENSG00000101901(ALG13) " oogenesis stage , spermatogenesis && adult stage , adult stage | male , oogenesis stage && adult stage | female , adult stage | female , pupal stage , pupal stage | late , oogenesis stage | stage S1-8 && adult stage | female " " egg chamber

, testis

, ovary

" " adult stage && oogenesis stage , oogenesis stage && adult stage | female " " germarium

, germarium region 2

, germarium region 1

, cystocyte

, ovary

, nurse cell

, oocyte

" "fertile,female sterile,recessive,female fertile,partially,wild-type,courtship behavior defective,female,female sterile germline-dependent,short lived,lethal,heat sensitive,male sterile,tumorigenic,partially lethal - majority die,some die during pupal stage" "egg chamber,ovary,nuclear chromosome,ovariole,nurse cell,egg,dorsal appendage,ectopic,nurse cell & nucleus,nurse cell & nuclear chromosome,germline cell,germarium,fusome,polytene chromosome band & nurse cell | ectopic,nurse cell ring canal,nurse follicle cell,oocyte" FBgn0038196 CG9922 http://flybase.net/reports/FBgn0038196.html "FBgn0045152, FBgn0047091" protein_coding_gene "BcDNA:RE55111, NEST:bs28g09" CG9922 16-Dec-15 2015_12 ENSDARG00000059725(zgc:171549) WBGene00008768(F13G3.10) ENSXETG00000015486(HYPK) ENSMUSG00000027245(2310003F16Rik) ENSG00000140264(SERF2) viable FBgn0003638 su(wa) suppressor of white-apricot http://flybase.net/reports/FBgn0003638.html protein_coding_gene 0003723=RNA binding "0006396=RNA processing, 0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0005681=spliceosomal complex" "su(w[a])-1, suppressor of apricot, su(w[a])-2, SWAP, EG:BACR7A4.10, su-w, su(wa), su[wa], CG3019, DmSWAP, su(w)" "IPR019147=Suppressor of white apricot N-terminal domain, IPR000061=SWAP/Surp" CG3019 16-Dec-15 2015_12 ENSDARG00000005980(srsf8) WBGene00006359(swp-1) ENSXETG00000009350(SFRS8) ENSMUSG00000029439(Srsf8) ENSG00000061936(SFSWAP) " embryonic stage | >3hr , embryonic stage | 0-3hr " "wild-type,visible,heat sensitive,viable" "pigment cell,heat sensitive,mesothoracic tergum" FBgn0069993 BG01862 BG01862 http://flybase.net/reports/FBgn0069993.html gene 16-Dec-15 2015_12 stress response defective FBgn0040899 CG17776 http://flybase.net/reports/FBgn0040899.html protein_coding_gene IPR029208=Cytochrome c oxidase assembly protein COX14 CG17776 16-Dec-15 2015_12 viable FBgn0035196 CG9129 http://flybase.net/reports/FBgn0035196.html protein_coding_gene CG9129 16-Dec-15 2015_12 visible "antenna,leg,ectopic" FBgn0016983 smid smallminded http://flybase.net/reports/FBgn0016983.html "FBgn0011034, FBgn0011393, FBgn0011406, FBgn0024837" protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" "0009267=cellular response to starvation, 0022008=neurogenesis" "CG8571, small-minded, l(3)j8A6, l(3)j6B8, l(3)s2898, Smid" "IPR003959=ATPase, AAA-type, core, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003960=ATPase, AAA-type, conserved site, IPR003593=AAA+ ATPase domain" CG8571 16-Dec-15 2015_12 ENSDARG00000025605(nvl) YLL034C(RIX7) ENSMUSG00000026516(Nvl) embryonic stage -- adult stage "locomotor rhythm defective,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal,decreased cell number,somatic clone,neuroanatomy defective,viable,visible" "embryonic/larval central nervous system,embryonic/larval brain,neuroblast,central nervous system,somatic clone,ganglion mother cell,trichogen cell" FBgn0032248 Bug22 Basal body up regulated gene 22 ortholog http://flybase.net/reports/FBgn0032248.html protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0048813=dendrite morphogenesis, 0048666=neuron development, 0006355=regulation of transcription, DNA-templated, 0040011=locomotion, 0000398=mRNA splicing, via spliceosome, 0018094=protein polyglycylation, 0007291=sperm individualization, 0044782=cilium organization, 0007517=muscle organ development" "0071011=precatalytic spliceosome, 0036126=sperm flagellum, 0005634=nucleus, 0005730=nucleolus, 0005929=cilium, 0071013=catalytic step 2 spliceosome" CG5343 IPR007714=Cilia/flagella-associated protein 20/WDR90/C3orf67 CG5343 16-Dec-15 2015_12 ENSDARG00000039193(zgc:73380) WBGene00008288(C54C6.6) ENSMUSG00000031796(Gtl3) ENSG00000070761(C16orf80) "short lived,uncoordinated,locomotor behavior defective,gravitaxis defective,visible,male sterile,viable" "wing,primary spermatocyte,elongation stage spermatid,centriole,ciliary basal body,sperm flagellum,spermatid axoneme,cystic bulge,sperm individualization complex,waste bag,Nebenkern derivative" FBgn0027889 ball ballchen http://flybase.net/reports/FBgn0027889.html protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0035184=histone threonine kinase activity, 0005524=ATP binding" "0016572=histone phosphorylation, 0036098=male germ-line stem cell maintenance, 0036099=female germ-line stem cell maintenance, 0097150=neuronal stem cell maintenance, 0006468=protein phosphorylation, 2001020=regulation of response to DNA damage stimulus, 0018107=peptidyl-threonine phosphorylation, 0007143=female meiotic division, 0022008=neurogenesis, 0030717=karyosome formation" 0005730=nucleolus "trip, triplet, NHK-1, nhk-1, nuclear histone kinase-1, NHK1, CG6386, Ball, nucleosomal histone kinase-1, BcDNA:LD09009, VRK, BALL, Ballchen" "IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain" CG6386 16-Dec-15 2015_12 "ENSDARG00000018006(vrk1),ENSDARG00000056231,ENSDARG00000021547(vrk2)" WBGene00017895(vrk-1) "ENSXETG00000013948(VRK1),ENSXETG00000020477(VRK2)" "ENSMUSG00000021115(Vrk1),ENSMUSG00000064090(Vrk2)" "ENSG00000100749(VRK1),ENSG00000028116(VRK2)" "female sterile,meiotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,mitotic cell cycle defective,male sterile,recessive,viable,female semi-fertile" "spindle,spindle pole,condensed chromosome,imaginal disc,embryonic/larval brain,karyosome,testis,polar body nucleus,maternal effect,stage S14 oocyte & meiotic metaphase I,stage S14 oocyte & meiotic metaphase ITl-I),embryonic/larval neuroblast,ganglion mother cell" FBgn0032906 RPA2 Replication protein A2 http://flybase.net/reports/FBgn0032906.html protein_coding_gene 0003677=DNA binding "0022008=neurogenesis, 0006261=DNA-dependent DNA replication, 0006310=DNA recombination, 0006281=DNA repair" 0005662=DNA replication factor A complex "dRPA2, 153194_at, RpA2, CG9273, replication protein A, subunit 2" "IPR012340=Nucleic acid-binding, OB-fold, IPR014892=Replication protein A, C-terminal, IPR014646=Replication factor A protein 2, IPR011991=Winged helix-turn-helix DNA-binding domain" CG9273 16-Dec-15 2015_12 ENSDARG00000037188(rpa2) YNL312W(RFA2) ENSXETG00000001834(rpa2) ENSMUSG00000028884(Rpa2) "ENSG00000117748(RPA2),ENSG00000204086(RPA4)" "lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "larval outer optic anlage,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,lamina anlage,medulla anlage,larval optic anlage" FBgn0004403 RpS14a Ribosomal protein S14a http://flybase.net/reports/FBgn0004403.html "FBgn0002584, FBgn0025283, FBgn0025314, FBgn0025318, FBgn0025321, FBgn0029981, FBgn0066849, FBgn0066850" protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "anon-EST:Posey115, CG1524, anon-EST:Posey77, RPS14A, S14, S14a, anon-EST:Posey154, rpS14A, 40S ribosomal protein S14, anon-WO03040301.136, anon-WO03040301.138, RpS14A, anon-EST:Posey131, Rp S14a, RpS14" "IPR018102=Ribosomal S11, conserved site, IPR001971=Ribosomal protein S11" CG1524 16-Dec-15 2015_12 ENSDARG00000036629(rps14) "YJL191W(RPS14B),YCR031C(RPS14A)" WBGene00004483(rps-14) ENSXETG00000015815(RPS14) "ENSMUSG00000024608(Rps14),ENSMUSG00000061848(Gm5805)" ENSG00000164587(RPS14) DRSC18710 EK -1.205853618 0.239450513 3.760855557 -2.45490761 0.308212095 2.314979891 FBgn0053105 p24-2 p24-related-2 http://flybase.net/reports/FBgn0053105.html FBgn0037732 protein_coding_gene 0005215=transporter activity "0000003=reproduction, 0048193=Golgi vesicle transport, 0006810=transport, 0048042=regulation of post-mating oviposition" "0016021=integral component of membrane, 0005794=Golgi apparatus" "p24, CG33105, CG9443" "IPR015720=TMP21-related, IPR009038=GOLD domain" CG33105 16-Dec-15 2015_12 "ENSDARG00000024954(tmed4),ENSDARG00000004261(tmed9)" "YGL002W(ERP6),YAR002C-A(ERP1),YHR110W(ERP5)" WBGene00013360(Y60A3A.9) "ENSXETG00000018999(tmed4),ENSXETG00000006739(tmed9)" ENSMUSG00000004394(Tmed4) "ENSG00000158604(TMED4),ENSG00000184840(TMED9)" "partially lethal - majority die,viable,male semi-sterile" FBgn0263607 l(3)72Dp lethal (3) 72Dp http://flybase.net/reports/FBgn0263607.html "FBgn0005548, FBgn0052155, FBgn0036582" protein_coding_gene 0008242=omega peptidase activity 0006541=glutamine metabolic process "CG32155, CG5082" "IPR029062=Class I glutamine amidotransferase-like, IPR015527=Peptidase C26, gamma-glutamyl hydrolase, IPR011697=Peptidase C26" CG32155 16-Dec-15 2015_12 "ENSDARG00000025237(LOC553228),ENSDARG00000071672(zgc:171566)" "ENSXETG00000015157(),ENSXETG00000021654(Q5BKJ9_XENTR)" ENSMUSG00000073987(Ggh) ENSG00000137563(GGH) FBgn0037074 CG7324 http://flybase.net/reports/FBgn0037074.html protein_coding_gene "0005509=calcium ion binding, 0005096=GTPase activator activity" 0043087=regulation of GTPase activity "IPR004182=GRAM domain, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR000195=Rab-GTPase-TBC domain" CG7324 16-Dec-15 2015_12 "ENSDARG00000059900(tbc1d9),ENSDARG00000043627,ENSDARG00000062192(si:dkey-110k5.6)" WBGene00012868(tbc-9) "ENSXETG00000014933(TBC1D9),ENSXETG00000015920()" "ENSMUSG00000031709(Tbc1d9),ENSMUSG00000036644(Tbc1d9b),ENSMUSG00000042473(Tbc1d8b),ENSMUSG00000003134(Tbc1d8)" "ENSG00000109436(TBC1D9),ENSG00000197226(TBC1D9B),ENSG00000133138(TBC1D8B),ENSG00000204634(TBC1D8)" viable DRSC11820 E -0.085879976 -0.429447272 -0.593927563 1.651116823 0.796728645 -0.169658213 FBgn0037347 CG1427 http://flybase.net/reports/FBgn0037347.html protein_coding_gene "0016785=transferase activity, transferring selenium-containing groups" 0097056=selenocysteinyl-tRNA(Sec) biosynthetic process SecS "IPR019872=O-phosphoseryl-tRNA(Sec) selenium transferase, IPR008829=SepSecS/SepCysS family, IPR015424=Pyridoxal phosphate-dependent transferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG1427 16-Dec-15 2015_12 ENSDARG00000033861(sepsecs) WBGene00008379(secs-1) ENSXETG00000002119(Q6DIU9_XENTR) ENSMUSG00000029173(Sepsecs) ENSG00000109618(SEPSECS) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0036082 CG12362 http://flybase.net/reports/FBgn0036082.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process AAN11912.1 "IPR001841=Zinc finger, RING-type, IPR002867=IBR domain, IPR031127=E3 ubiquitin ligase RBR family, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG12362 16-Dec-15 2015_12 YKR017C() "WBGene00016158(ari-1),WBGene00016156(C27A12.6),WBGene00016157(C27A12.7),WBGene00013538(tag-349)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0261049 Vps45 Vacuolar protein sorting 45 http://flybase.net/reports/FBgn0261049.html "FBgn0260566, FBgn0260863, FBgn0042683, FBgn0037711" protein_coding_gene "0005515=protein binding, 0000149=SNARE binding" "0007269=neurotransmitter secretion, 0007040=lysosome organization, 0034058=endosomal vesicle fusion, 0048227=plasma membrane to endosome transport, 0016192=vesicle-mediated transport, 0006605=protein targeting, 0016082=synaptic vesicle priming, 0006904=vesicle docking involved in exocytosis, 0006897=endocytosis, 0006886=intracellular protein transport" "0008021=synaptic vesicle, 0005769=early endosome" "MENE(3R)-C, DmVps45, Vps45p, dVps45, VPS45, CG8228, MENE (3R)-C, Vps45" "IPR027482=Sec1-like, domain 2, IPR001619=Sec1-like protein" CG8228 16-Dec-15 2015_12 ENSDARG00000061180(vps45) YGL095C(VPS45) WBGene00016643(vps-45) ENSXETG00000015753(VPS45) ENSMUSG00000015747(Vps45) ENSG00000136631(VPS45) "lethal - all die before end of larval stage,recessive,some die during larval stage,visible" "eye disc,somatic clone,posterior wing margin,wing vein,yolk granule | germline clone" FBgn0039160 CG5510 http://flybase.net/reports/FBgn0039160.html protein_coding_gene "0012505=endomembrane system, 0016020=membrane" "IPR005052=Legume-like lectin, IPR013320=Concanavalin A-like lectin/glucanase domain" CG5510 16-Dec-15 2015_12 "ENSDARG00000061854(lman2),ENSDARG00000006014" "YLR080W(EMP46),YFL048C(EMP47)" WBGene00002071(ile-2) "ENSXETG00000001248(BC088517.1),ENSXETG00000006741(LMAN2)" "ENSMUSG00000021484(Lman2),ENSMUSG00000001143(Lman2l)" "ENSG00000169223(LMAN2),ENSG00000114988(LMAN2L)" DRSC15823 I 1.685934378 -0.150751742 -0.043910513 -0.188621639 -0.385889139 -0.757455793 FBgn0000455 Dip-C Dipeptidase C http://flybase.net/reports/FBgn0000455.html FBgn0038040 protein_coding_gene "0030145=manganese ion binding, 0016805=dipeptidase activity, 0008239=dipeptidyl-peptidase activity" 0006508=proteolysis "CG5663, dipC" "IPR007865=Aminopeptidase P, N-terminal, IPR000994=Peptidase M24, structural domain, IPR001131=Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site, IPR028980=Creatinase/Aminopeptidase P, N-terminal, IPR029149=Creatinase/Aminopeptidase P/Spt16, N-terminal" CG5663 16-Dec-15 2015_12 ENSDARG00000018020(pepd) YFR006W() WBGene00019673(K12C11.1) ENSXETG00000018297(pepd) ENSMUSG00000063931(Pepd) ENSG00000124299(PEPD) viable FBgn0267911 trol terribly reduced optic lobes http://flybase.net/reports/FBgn0267911.html "FBgn0261451, FBgn0001402, FBgn0027946, FBgn0029620, FBgn0029621, FBgn0040379, FBgn0040380, FBgn0040381, FBgn0045878, FBgn0053675, FBgn0053950, FBgn0063205, FBgn0026710, FBgn0027241, FBgn0028307, FBgn0086539" protein_coding_gene "0072347=response to anesthetic, 0055059=asymmetric neuroblast division, 0007415=defasciculation of motor neuron axon, 0045199=maintenance of epithelial cell apical/basal polarity, 2001262=positive regulation of semaphorin-plexin signaling pathway, 0008045=motor neuron axon guidance" "0005829=cytosol, 0005811=lipid particle, 0005654=nucleoplasm, 0005604=basement membrane, 0005578=proteinaceous extracellular matrix" "perlecan, CT23996, l(1)zwl, l(1)zw1, anon-WO0153538.72, Terribly reduced optic lobes, EG:BACR25B3.11, dPerlecan, Trol, mRNA-like ncRNA in embryogenesis 7, MRE7, Pcan, lethal (1) G0374, l(1)VA51, l(1)G0271, ZW-1, Trol-B, zw1, EG:BACR25B3.2, Trol/perlecan, lethal (1) G0271, troll, zw-1, EG:BACR25B3.10, CG12497, GC7891, EG:BACR25B3.1, Trol-A, Troll, pcan, BcDNA:GM02481, l(1)G0023, CG33950, CG7981, terribly reduced optic lobes, l(1)3Ac, lethal (1) G0023, l(1)9-96, l(1)G0374, CG33675, Perlecan, l(1)trol" "IPR000034=Laminin IV, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR000742=EGF-like domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR013032=EGF-like, conserved site, IPR013151=Immunoglobulin, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002049=Laminin EGF domain" CG33950 16-Dec-15 2015_12 WBGene00006787(unc-52) ENSXETG00000017911(HSPG2) FBgn0039475 CG6277 http://flybase.net/reports/FBgn0039475.html protein_coding_gene "0008970=phosphatidylcholine 1-acylhydrolase activity, 0016298=lipase activity" "0016042=lipid catabolic process, 0022008=neurogenesis" "Triglyceride lipase, DmelL2" "IPR013818=Lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold, IPR000734=Triacylglycerol lipase family, IPR002334=Vespid venom allergen phospholipase A1" CG6277 16-Dec-15 2015_12 ENSXETG00000018070(PLA1A) "viable,lethal,neuroanatomy defective,visible" "ganglion mother cell,embryonic/larval neuroblast,trichogen cell" FBgn0015230 Glut3 Glucose transporter type 3 http://flybase.net/reports/FBgn0015230.html protein_coding_gene 0005355=glucose transmembrane transporter activity "0055085=transmembrane transport, 0015758=glucose transport" 0016021=integral component of membrane "CG3853, GLU, glut-l, Glucose transporter-like" "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like" CG3853 16-Dec-15 2015_12 "YLR081W(GAL2),YDR343C(HXT6),YDR342C(HXT7),YHR092C(HXT4),YJL214W(HXT8),YDR345C(HXT3),YHR094C(HXT1),YHR096C(HXT5),YJL219W(HXT9),YOL156W(HXT11),YMR011W(HXT2),YFL011W(HXT10),YNR072W(HXT17),YEL069C(HXT13),YDL245C(HXT15),YJR158W(HXT16)" viable DRSC16681 K 0.628305853 -0.380270276 0.950980011 -0.191236658 2.500965378 0.394396089 FBgn0020389 Papss PAPS synthetase http://flybase.net/reports/FBgn0020389.html protein_coding_gene "0004781=sulfate adenylyltransferase (ATP) activity, 0005524=ATP binding, 0004020=adenylylsulfate kinase activity" "0007476=imaginal disc-derived wing morphogenesis, 0000103=sulfate assimilation" 0005654=nucleoplasm "PAPS, papss, paps synthetase, CG8363, DmPAPSS, l(3)76BDn, Paps, paps, PAPSS, PAPs synthase" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR024951=Sulphate adenylyltransferase catalytic domain, IPR002891=Adenylyl-sulfate kinase, IPR015947=PUA-like domain, IPR002650=Sulphate adenylyltransferase, IPR025980=ATP-sulfurylase PUA-like domain, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG8363 16-Dec-15 2015_12 "ENSDARG00000056600(papss2b),ENSDARG00000071021(papss2a),ENSDARG00000057099(papss1)" YJR010W(MET3) WBGene00004091(pps-1) "ENSXETG00000019855(papss1),ENSXETG00000009264(PAPSS2)" "ENSMUSG00000024899(Papss2),ENSMUSG00000028032(Papss1)" "ENSG00000198682(PAPSS2),ENSG00000138801(PAPSS1)" "lethal,recessive,chemical sensitive,dominant,visible,viable" "presumptive embryonic salivary gland,embryonic/first instar larval cuticle,germline clone,somatic clone,wing,posterior compartment" DRSC27101 K -0.575140183 0.043480878 -0.048483649 0.404755807 1.731135212 -0.967915749 FBgn0035936 Tsp66E Tetraspanin 66E http://flybase.net/reports/FBgn0035936.html protein_coding_gene "0005886=plasma membrane, 0016021=integral component of membrane" "Dm.Tsp66E, CG4999" "IPR008952=Tetraspanin, EC2 domain, IPR018503=Tetraspanin, conserved site, IPR018499=Tetraspanin/Peripherin, IPR000301=Tetraspanin" CG4999 16-Dec-15 2015_12 "ENSDARG00000019098(zgc:73292),ENSDARG00000026070(cd82)" WBGene00006637(tsp-11) "ENSXETG00000022237(cd82),ENSXETG00000003177(cd37),ENSXETG00000004371(tspan1)" ENSMUSG00000027217(Tspan18) "ENSG00000085117(CD82),ENSG00000104894(CD37)" "lethal,maternal effect,some die during embryonic stage,viable" "egg,maternal effect" FBgn0047178 CG32147 http://flybase.net/reports/FBgn0047178.html FBgn0052147 protein_coding_gene 0016920=pyroglutamyl-peptidase activity 0006508=proteolysis 0005829=cytosol BcDNA:RE07960 "IPR000816=Peptidase C15, pyroglutamyl peptidase I, IPR016125=Peptidase C15, pyroglutamyl peptidase I-like" CG32147 16-Dec-15 2015_12 "ENSDARG00000054666(pgpep1),ENSDARG00000041092(si:dkey-25f3.4)" "WBGene00010858(M04C9.3),WBGene00010857(M04C9.2),WBGene00010856(M04C9.1)" "ENSXETG00000014629(Q6DIL3_XENTR),ENSXETG00000002109(PGPEP1L)" ENSMUSG00000056204(Pgpep1) "ENSG00000130517(PGPEP1),ENSG00000183571(PGPEP1L)" viable FBgn0039204 CG6607 http://flybase.net/reports/FBgn0039204.html protein_coding_gene "IPR019348=Uncharacterised domain KLRAQ/TTKRSYEDQ, C-terminal, IPR019343=Uncharacterised domain KLRAQ/TTKRSYEDQ, N-terminal" CG6607 16-Dec-15 2015_12 ENSDARG00000027853(zgc:92087) WBGene00018011(F33E11.3) ENSXETG00000022652(KLRAQ1) ENSMUSG00000034709(Klraq1) ENSG00000162869(KLRAQ1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0029152 Mkrn1 Makorin 1 http://flybase.net/reports/FBgn0029152.html FBgn0037095 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0000209=protein polyubiquitination "CG7184, MKRN1" "IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000571=Zinc finger, CCCH-type, IPR001841=Zinc finger, RING-type" CG7184 16-Dec-15 2015_12 "ENSDARG00000041665(mkrn1),ENSDARG00000007630(mkrn2)" WBGene00021924(Y55F3AM.6) ENSXETG00000027117() "ENSMUSG00000029922(Mkrn1),ENSMUSG00000070527(Mkrn3),ENSMUSG00000000439(Mkrn2)" "ENSG00000133606(MKRN1),ENSG00000179455(MKRN3),ENSG00000075975(MKRN2)" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0025865 Cortactin Cortactin http://flybase.net/reports/FBgn0025865.html protein_coding_gene 0070064=proline-rich region binding "0008360=regulation of cell shape, 0048260=positive regulation of receptor-mediated endocytosis, 0007301=female germline ring canal formation, 0007010=cytoskeleton organization, 0007298=border follicle cell migration" "0043234=protein complex, 0030478=actin cap, 0005856=cytoskeleton, 0005886=plasma membrane, 0070864=sperm individualization complex" "cortactin, cttn, CG3637, DCortactin" "IPR003134=Hs1/Cortactin, IPR001452=SH3 domain" CG3637 16-Dec-15 2015_12 "ENSDARG00000012729(si:dkey-9a20.6),ENSDARG00000011777(cttn)" "ENSXETG00000003797(CTTN),ENSXETG00000015412(Q5M8F8_XENTR)" ENSMUSG00000022831(Hcls1) ENSG00000180353(HCLS1) embryonic stage -- adult stage "viable,fertile,female fertile,reduced" "nurse cell ring canal,egg,nurse follicle cell,border follicle cell,cell autonomous,somatic clone,actin filament | ectopic" FBgn0031881 CG3476 http://flybase.net/reports/FBgn0031881.html protein_coding_gene "0005476=carnitine:acyl carnitine antiporter activity, 0022857=transmembrane transporter activity" "0006844=acyl carnitine transport, 0055085=transmembrane transport, 0006839=mitochondrial transport, 0015879=carnitine transport" "0031966=mitochondrial membrane, 0005743=mitochondrial inner membrane" "IPR018108=Mitochondrial substrate/solute carrier, IPR002067=Mitochondrial carrier protein, IPR023395=Mitochondrial carrier domain" CG3476 16-Dec-15 2015_12 ENSDARG00000071052(si:dkey-150i13.2) YOR100C(CRC1) WBGene00000996(dif-1) ENSXETG00000009331(slc25a20) ENSMUSG00000032602(Slc25a20) ENSG00000178537(SLC25A20) viable FBgn0011762 DNApol-ë±50 DNA polymerase ë± 50kD http://flybase.net/reports/FBgn0011762.html FBgn0044611 protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0003896=DNA primase activity" "0006269=DNA replication, synthesis of RNA primer, 0006260=DNA replication, 0022008=neurogenesis" 0005658=alpha DNA polymerase:primase complex "POLA, PRI1, Pol, polalpha, DNApolalpha, Polalpha 50kDa, Dpri50, anon-WO0140519.257, DNA polymerase 50K, DNA polymerase alpha 46,000 gamma subunit, DNA polymerase alpha 50 kda primase subunit, DNApol-alpha50, p50 subunit of DNA polymerase alpha, DNApolalpha50, DNA polalpha, dnapol alpha 50, polalpha50, DNA polymerase alpha 50,000 gamma subunit, Polalpha, pol alpha, DNApol-alpha, DNA-polymerase alpha, Dmpol alpha, CG7108, DNA polymerase alpha" "IPR014052=DNA primase, small subunit, eukaryotic/archaeal, IPR002755=DNA primase, small subunit" CG7108 16-Dec-15 2015_12 ENSDARG00000040163(prim1) YIR008C(PRI1) "WBGene00004180(pri-1),WBGene00020761(T24C4.5)" ENSXETG00000025421(prim1) ENSMUSG00000025395(Prim1) ENSG00000198056(PRIM1) "lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,eye" FBgn0266053 Patr-1 Protein associated with topo II related - 1 http://flybase.net/reports/FBgn0266053.html "FBgn0028470, FBgn0062120, FBgn0010888" protein_coding_gene "0000290=deadenylation-dependent decapping of nuclear-transcribed mRNA, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0033962=cytoplasmic mRNA processing body assembly" "0005737=cytoplasm, 0000932=cytoplasmic mRNA processing body" "patr-1, l(3)06442, BcDNA:LD27979, CG5208, hpat, LD27979, lethal (3) 06442, anon-WO0118547.282, HPat" CG5208 16-Dec-15 2015_12 ENSDARG00000017423(zgc:158239) WBGene00009661(patr-1) "ENSXETG00000014167(PATL2),ENSXETG00000011944(PATL1)" "ENSMUSG00000046139(Patl1),ENSMUSG00000027233(Patl2)" ENSG00000166889(PATL1) DRSC14159 K -0.153652138 -0.920681032 -0.963285195 0.158747694 1.513970493 1.246982516 FBgn0034350 CG5189 http://flybase.net/reports/FBgn0034350.html protein_coding_gene "0032947=protein complex scaffold, 0005085=guanyl-nucleotide exchange factor activity" "0034613=cellular protein localization, 0071230=cellular response to amino acid stimulus, 0016049=cell growth" "0071986=Ragulator complex, 0005794=Golgi apparatus" "dp14, p14" IPR004942=Roadblock/LAMTOR2 domain CG5189 16-Dec-15 2015_12 ENSDARG00000039872(zgc:100811) WBGene00022402(Y97E10AR.7) ENSXETG00000026049(mapbpip) ENSMUSG00000028062(Robld3) ENSG00000116586(LAMTOR2) "viable,visible" trichogen cell FBgn0033021 CG10417 http://flybase.net/reports/FBgn0033021.html FBan0010417 protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0043169=cation binding" 0006470=protein dephosphorylation 0005737=cytoplasm PP2Cg "IPR001932=PPM-type phosphatase domain, IPR015655=Protein phosphatase 2C, IPR000222=PPM-type phosphatase, divalent cation binding" CG10417 16-Dec-15 2015_12 "YBL056W(PTC3),YER089C(PTC2)" WBGene00018362(F42G9.1) ENSXETG00000020949(BC090129.1) ENSMUSG00000029147(Ppm1g) ENSG00000115241(PPM1G) DRSC04846 K 1.158956107 0.438035251 0.204756774 0.52779196 -0.037511391 1.522519248 FBgn0022355 Tsf1 Transferrin 1 http://flybase.net/reports/FBgn0022355.html FBgn0025536 protein_coding_gene "0005381=iron ion transmembrane transporter activity, 0008199=ferric iron binding" "0006952=defense response, 0042048=olfactory behavior, 0009620=response to fungus, 0006879=cellular iron ion homeostasis, 0006826=iron ion transport" "0005886=plasma membrane, 0005576=extracellular region" "CG6186, TSF1, tsf1, lincRNA.S9601, anon-EST:Posey265, 143958_at, Transferrin, Transferrin1, DTAF-transferrin, transferrin, Trf, Transferrin 1, Tf, transferrin precursor, transferrin 1" "IPR001156=Transferrin-like domain, IPR018195=Transferrin family, iron binding site" CG6186 16-Dec-15 2015_12 "ENSMUSG00000022780(Mfi2),ENSMUSG00000032496(Ltf),ENSMUSG00000032554(Trf),ENSMUSG00000033688(1300017J02Rik)" "viable,fertile" DRSC20296 K -0.344039503 -0.145976112 0.076732204 0.395162191 -2.085982212 0.332887738 FBgn0034538 CG16799 http://flybase.net/reports/FBgn0034538.html protein_coding_gene 0003796=lysozyme activity "0019730=antimicrobial humoral response, 0006952=defense response" "IPR023346=Lysozyme-like domain, IPR001916=Glycoside hydrolase, family 22, IPR019799=Glycoside hydrolase, family 22, conserved site" CG16799 16-Dec-15 2015_12 ENSDARG00000057789(lyz) "ENSG00000151033(LYZL2),ENSG00000120563(LYZL1),ENSG00000141316(SPACA3),ENSG00000171478(SPACA5B),ENSG00000171489(SPACA5),ENSG00000161572(LYZL6),ENSG00000157093(LYZL4)" "viable,fertile" FBgn0032297 CG17124 http://flybase.net/reports/FBgn0032297.html FBgn0062210 protein_coding_gene 0004864=protein phosphatase inhibitor activity 0042325=regulation of phosphorylation 0005737=cytoplasm anon-WO0118547.153 IPR008025=PKC-activated phosphatase-1 inhibitor CG17124 16-Dec-15 2015_12 "ENSDARG00000030161(ppp1r14b),ENSDARG00000044541(zgc:153208),ENSDARG00000054817(zgc:109984),ENSDARG00000017710(zgc:73377),ENSDARG00000011239(ppp1r14a)" WBGene00010109(F55C10.5) "ENSXETG00000007199(ppp1r14b),ENSXETG00000022545(PPP1R14C),ENSXETG00000000157(ppp1r14a)" "ENSMUSG00000056612(Ppp1r14b),ENSMUSG00000073730(4933415F23Rik),ENSMUSG00000040653(Ppp1r14c),ENSMUSG00000037166(Ppp1r14a)" "ENSG00000173457(PPP1R14B),ENSG00000198729(PPP1R14C),ENSG00000167641(PPP1R14A),ENSG00000166143(PPP1R14D)" "viable,fertile" FBgn0041789 Pax Paxillin http://flybase.net/reports/FBgn0041789.html "FBgn0032776, FBgn0032777, FBgn0051794" protein_coding_gene 0008270=zinc ion binding "0007016=cytoskeletal anchoring at plasma membrane, 0046843=dorsal appendage formation, 0043087=regulation of GTPase activity, 1901739=regulation of myoblast fusion, 0035218=leg disc development, 0035220=wing disc development, 0010506=regulation of autophagy" "0005925=focal adhesion, 0005829=cytosol, 0005927=muscle tendon junction" "CG31794, PDLP, Paxillin, CT42454, Paxillin-derived LIM-only protein, Paxilin, Pax-derived LIM only protein, DPaxillin, DPxn, dPax, Dpax, paxillin, CT40481, DPxn37, DpaxA, paxillin-derived LIM-only protein, CG18576, D-Paxillin, CG18061, pax" "IPR001781=Zinc finger, LIM-type" CG31794 16-Dec-15 2015_12 "ENSDARG00000060766,ENSDARG00000058391(pxn)" ENSXETG00000012201() ENSMUSG00000029528(Pxn) ENSG00000140682(TGFB1I1) larval stage | third instar muscle fiber | vicinity of muscle attachment site

"viable,fertile,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,lethal,heat sensitive,visible,partially lethal - majority live" "egg chamber,conditional,dorsal appendage,autophagic vacuolepr-A16),fat body,embryonic myoblast,embryonic/larval epidermis,heat sensitive,wing vein,ectopic,wing,leg,ventral transverse muscle 1,dorsal transverse muscle,dorsal acute muscle 1,nucleus | supernumeraryeve.eme,ventral acute muscle 2" FBgn0001296 kar karmoisin http://flybase.net/reports/FBgn0001296.html FBgn0038077 protein_coding_gene 0008028=monocarboxylic acid transmembrane transporter activity "0006727=ommochrome biosynthetic process, 0055085=transmembrane transport" "0016021=integral component of membrane, 0005886=plasma membrane" CG12286 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG12286 16-Dec-15 2015_12 ENSDARG00000020984(slc16a10) "ENSXETG00000021337(SLC16A10),ENSXETG00000004581(SLC16A2)" "ENSMUSG00000019838,ENSMUSG00000033965(Slc16a2)" "ENSG00000112394(SLC16A10),ENSG00000147100(SLC16A2)" "viable,fertile,eye color defective,recessive,visible" "pigment cell,ocellus,ocellus pigment granule,Malpighian tubule" FBgn0004701 l(2)56Fb lethal (2) 56Fb http://flybase.net/reports/FBgn0004701.html gene "l(2)12, l(2)56F" 16-Dec-15 2015_12 "lethal,recessive" FBgn0027660 blot bloated tubules http://flybase.net/reports/FBgn0027660.html protein_coding_gene "0005328=neurotransmitter:sodium symporter activity, 0005326=neurotransmitter transporter activity" "0002009=morphogenesis of an epithelium, 0006836=neurotransmitter transport" 0016021=integral component of membrane "CG3897, DmBLOT, l(3)1658, Blated tubules" IPR000175=Sodium:neurotransmitter symporter CG3897 16-Dec-15 2015_12 "viable,fertile,lethal,female fertile,germline clone,reduced,non-rescuable maternal effect,recessive,lethal - all die before end of larval stage,some die during larval stage" "denticle,Malpighian tubule,blastoderm embryo,germline clone,pole cell" FBgn0023509 mip130 Myb-interacting protein 130 http://flybase.net/reports/FBgn0023509.html protein_coding_gene 0003677=DNA binding "0007307=eggshell chorion gene amplification, 0090307=mitotic spindle assembly, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007052=mitotic spindle organization, 0051297=centrosome organization" "0005700=polytene chromosome, 0000785=chromatin, 0017053=transcriptional repressor complex, 0031523=Myb complex, 0005634=nucleus, 0005737=cytoplasm" "CG3480, EG:86E4.4, Mip130/TWIT, twit, Twit, 86E4.4, twilight, Mip130, TWIT" IPR010561=Protein LIN-9/Protein ALWAYS EARLY CG3480 16-Dec-15 2015_12 "ENSDARG00000028475(lin9),ENSDARG00000069253(LOC100330674)" WBGene00002998(lin-9) ENSXETG00000022620(LIN9) ENSG00000183814(LIN9) "viable,small body,female sterile,female semi-sterile,partially lethal - majority live" chorion DRSC18575 IE 4.627075262 -0.706870959 3.704869709 -2.205621722 0.408451166 -0.523679245 FBgn0033063 CG14589 http://flybase.net/reports/FBgn0033063.html protein_coding_gene CG14589 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027594 drpr draper http://flybase.net/reports/FBgn0027594.html FBgn0035261 protein_coding_gene "0005515=protein binding, 0001786=phosphatidylserine binding" "0008345=larval locomotory behavior, 0042742=defense response to bacterium, 0048678=response to axon injury, 0007155=cell adhesion, 0048190=wing disc dorsal/ventral pattern formation, 0016322=neuron remodeling, 0035212=cell competition in a multicellular organism, 0006909=phagocytosis, 0006911=phagocytosis, engulfment, 0060100=positive regulation of phagocytosis, engulfment, 0043652=engulfment of apoptotic cell, 0043277=apoptotic cell clearance, 0035071=salivary gland cell autophagic cell death" 0031224=intrinsic component of membrane "Draper, CG18172, CT41022, CT6730, Drpr, CG2086, BcDNA:GH03529, draper" "IPR002049=Laminin EGF domain, IPR011489=EMI domain, IPR013032=EGF-like, conserved site, IPR000742=EGF-like domain" CG2086 16-Dec-15 2015_12 "ENSDARG00000062686(megf11),ENSDARG00000017229" WBGene00000415(ced-1) "ENSXETG00000015852(MEGF11),ENSXETG00000018052(PEAR1)" "ENSMUSG00000024593(Megf10),ENSMUSG00000036466(Megf11)" "ENSG00000145794(MEGF10),ENSG00000157890(MEGF11)" "neuroanatomy defective,cell death defective,nutrition conditional,conditional,uncoordinated,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable,immune response defective,germline clone,increased cell death" "adult olfactory receptor neuron,embryonic/larval salivary gland,lysosomefkh.PH,ensheathing neuropil associated glial cell,egg chamber,nutrition conditional,follicle cell,reticular neuropil associated glial cell,gamma Kenyon cell,wing vein L1,conditional,glial cell,dendrite,embryonic hemocyte,dorsal multidendritic neuron ddaC,adult mushroom body,germline clone,dorsal multidendritic neuron ddaC | pupal stage,nurse cell" FBgn0013643 mfs(2)1 mfs(2)1 http://flybase.net/reports/FBgn0013643.html gene 16-Dec-15 2015_12 "male sterile,female sterile" FBgn0015791 Rab14 Rab14 http://flybase.net/reports/FBgn0015791.html "FBgn0014431, FBgn0027898" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0032456=endocytic recycling, 0015031=protein transport, 0090383=phagosome acidification, 0001845=phagolysosome assembly, 0016192=vesicle-mediated transport, 0032482=Rab protein signal transduction, 0042742=defense response to bacterium, 0006895=Golgi to endosome transport" "0045202=synapse, 0045335=phagocytic vesicle, 0031982=vesicle, 0005770=late endosome, 0055037=recycling endosome, 0005802=trans-Golgi network, 0005769=early endosome, 0043025=neuronal cell body" "57H4T, Rab-r14, anon-sts33, CG4212, AAF53390, Rab-protein 14, DRAB14, O18336, BG:DS01068.7, DmRab14, ESTS:57H4T, rab14, DRab14" "IPR003579=Small GTPase superfamily, Rab type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR030702=Ras-related protein Rab14" CG4212 16-Dec-15 2015_12 ENSDARG00000045261 WBGene00004276(rab-14) ENSXETG00000019811(rab14) ENSMUSG00000026878(Rab14) ENSG00000119396(RAB14) "fertile,immune response defective,viable,wild-type" "phagocytic vesicle,hemocyte,phagocytic vesicleHml.ëÓ,hemocyte | adult stage" FBgn0016794 dos daughter of sevenless http://flybase.net/reports/FBgn0016794.html protein_coding_gene "0005070=SH3/SH2 adaptor activity, 0005515=protein binding, 0042169=SH2 domain binding" "0008293=torso signaling pathway, 0046578=regulation of Ras protein signal transduction, 0045500=sevenless signaling pathway, 0008595=anterior/posterior axis specification, embryo, 0019730=antimicrobial humoral response" "0005886=plasma membrane, 0005737=cytoplasm" "CG1044, Gab-1, E(csw)3A, DOS, 141511_at, EC3-4, Enhancer of corkscrew-CS, Daughter of sevenless, Suppressor of sevenless-S11, Su(sev)3A, Daughter of Sevenless, Su(sev[S11])3A, E(csw[CS])3A, Dos" "IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG1044 16-Dec-15 2015_12 ENSDARG00000037018(gab1) "ENSXETG00000010452(),ENSXETG00000017549(GAB1),ENSXETG00000001527(GAB3)" "ENSMUSG00000004508(Gab2),ENSMUSG00000031714(Gab1),ENSMUSG00000032750(Gab3)" "ENSG00000109458(GAB1),ENSG00000033327(GAB2),ENSG00000160219(GAB3),ENSG00000215568(GAB4)" larval stage | third instar " eye-antennal disc

, morphogenetic furrow | posterior to

, morphogenetic furrow

" "viable,fertile,lethal,recessive,wild-type,partially lethal - majority die,some die during larval stage" "anterior crossvein,eye,photoreceptor cell R7,wing vein,wing vein L4,eye photoreceptor cell,filzkorper,germline clone,embryonic abdominal segment 8,embryonic head,Malpighian tubule,cephalopharyngeal skeleton,ommatidium,cone cell,somatic clone,A1-7 ventral acute muscle 2,precursor,photoreceptor" DRSC07992 IEK -2.12983894 -5.068627078 -2.202789088 -3.346431818 -6.72843955 -6.15132667 FBgn0034666 CG9294 http://flybase.net/reports/FBgn0034666.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP20 "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG9294 16-Dec-15 2015_12 "ENSDARG00000056324(zgc:123295),ENSDARG00000046140(zgc:112038),ENSDARG00000055644(zgc:101788),ENSDARG00000070713(zgc:162180),ENSDARG00000070710(wu:fk80d04),ENSDARG00000061858(zgc:153968),ENSDARG00000056773(zgc:163079),ENSDARG00000052064(LOC571079),ENSDARG00000063444,ENSDARG00000070518,ENSDARG00000019714" WBGene00006619(try-1) "ENSXETG00000006302(BC067937.1),ENSXETG00000006299(),ENSXETG00000025963(prss27),ENSXETG00000008526()" "ENSMUSG00000054537(Tmprss11e),ENSMUSG00000048764(Tmprss11f)" viable DRSC04537 I -0.037579649 1.975164906 0.259679419 0.270211738 -0.78941162 0.796179081 FBgn0025360 Optix Optix http://flybase.net/reports/FBgn0025360.html "FBgn0027365, FBgn0033251, FBgn0045871" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048813=dendrite morphogenesis, 0001751=compound eye photoreceptor cell differentiation, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0001745=compound eye morphogenesis" 0005634=nucleus "anon-WO0153538.79, opt, opx, D-Six3, OPTIX, six3, Dsix3, Six3, CG18455, optix" "IPR009057=Homeodomain-like, IPR001356=Homeobox domain" CG18455 16-Dec-15 2015_12 "ENSDARG00000054879(six3b),ENSDARG00000058008(six3a),ENSDARG00000025187(six6a),ENSDARG00000031316(six6b)" WBGene00000453(ceh-32) "ENSMUSG00000038805,ENSMUSG00000021099(Six6)" ENSG00000177045(SIX5) " embryonic stage , embryonic stage | stage 12,13 , larval stage | third instar , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage 6 , embryonic stage | early " " terminal organ

, head sensillum

, labral segment

, embryonic maxillary segment

, frontal ganglion

, embryonic stomatogastric nervous system

, eye-antennal disc

, ectoderm | dorsal

, dorsal pouch

, organism | 80-90% egg length

, clypeo-labral disc

, stomodeum

, labial organ

, supraesophageal ganglion | presumptive | dorsal to

, larval labral segment sense organ

, embryonic supraesophageal neuromere

, procephalic neurogenic region

, gonad

,

dorsal & anterior , organism | 80-100% egg length

, embryonic labial segment

" "lethal,lethal - all die during larval stage,recessive,visible,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye,somatic clone,eye disc,ectopic,antenna,wing,haltere,adult head,eye photoreceptor cell,dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB,ommatidium,eye disc & neuroney.PH,anterior,medial,interocellar bristle,ocellus" FBgn0035348 CG16758 http://flybase.net/reports/FBgn0035348.html FBgn0035349 protein_coding_gene 0004731=purine-nucleoside phosphorylase activity 0009116=nucleoside metabolic process "c62E-15, CG16760" "IPR001369=PNP/MTAP phosphorylase, IPR000845=Nucleoside phosphorylase domain, IPR011270=Purine nucleoside phosphorylase I, inosine/guanosine-specific, IPR011268=Purine nucleoside phosphorylase" CG16758 16-Dec-15 2015_12 "ENSDARG00000045201(pnp5a),ENSDARG00000019553(pnp5b),ENSDARG00000040942(pnp6),ENSDARG00000029230(pnp4b),ENSDARG00000057575(pnp4a)" YLR209C(PNP1) WBGene00019298(K02D7.1) ENSXETG00000016932(np) "ENSMUSG00000021871(Pnp),ENSMUSG00000068417(Pnp2)" ENSG00000198805(PNP) "viable,body color defective" mesothoracic tergum FBgn0010246 Myo61F Myosin 61F http://flybase.net/reports/FBgn0010246.html protein_coding_gene "0005524=ATP binding, 0003779=actin binding, 0003774=motor activity, 0042623=ATPase activity, coupled" "0042742=defense response to bacterium, 0048803=imaginal disc-derived male genitalia morphogenesis, 0007498=mesoderm development, 0007368=determination of left/right symmetry, 0032528=microvillus organization" "0005938=cell cortex, 0005903=brush border, 0016459=myosin complex, 0005737=cytoplasm" "IB, MyoIC, myosin 61F, MIB, DroMIB, myosin IB, Myosin-IB, myosin 1b, myosin-IB, Dm IB, unnamed, MYO61F, Myo1B, myosin 1B, CG9155, myosin I, Myo-IB, myosin61F, DmIB, Myosin IB, myo61F, Myosin61F, myo61f, MYOIB" "IPR001609=Myosin head, motor domain, IPR010926=Unconventional myosin tail, actin- and lipid-binding, IPR000048=IQ motif, EF-hand binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG9155 16-Dec-15 2015_12 "ENSDARG00000061579(myo1c),ENSDARG00000020924(si:ch211-69i14.4),ENSDARG00000061968(si:dkey-189p24.1)" "YKL129C(MYO3),YMR109W(MYO5)" "ENSXETG00000022882(MYO1C),ENSXETG00000018580()" ENSMUSG00000017774(Myo1c) "ENSG00000197879(MYO1C),ENSG00000174527(MYO1H)" embryonic stage -- adult stage " embryonic stage | late , oogenesis stage , embryonic stage -- adult stage , adult stage , embryonic stage " " gastric caecum

, posterior embryonic/larval midgut

, egg chamber

, mid embryonic/larval midgut

, centripetally migrating follicle cell

, embryonic/larval hindgut

, alimentary canal

, anterior embryonic/larval midgut

, embryonic/larval digestive system

, follicle cell

" "increased cell death,viable,axis specification defective" "embryonic/larval midgut primordium,embryonic hindgut,male genitalia,embryonic/larval midgut,enterocyte,brush border,microvillus" FBgn0052523 CG32523 http://flybase.net/reports/FBgn0052523.html FBgn0031167 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP50, CG1497" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG32523 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" FBgn0010350 CdsA CDP diglyceride synthetase http://flybase.net/reports/FBgn0010350.html FBgn0035841 protein_coding_gene 0004605=phosphatidate cytidylyltransferase activity "0016049=cell growth, 0043052=thermotaxis, 0007430=terminal branching, open tracheal system, 0019915=lipid storage, 0016056=rhodopsin mediated signaling pathway, 0010883=regulation of lipid storage, 0007602=phototransduction, 0016024=CDP-diacylglycerol biosynthetic process, 0060439=trachea morphogenesis" "0005887=integral component of plasma membrane, 0005790=smooth endoplasmic reticulum, 0005783=endoplasmic reticulum, 0005635=nuclear envelope, 0005886=plasma membrane" "CDP-DAG synthase, cytidine diphosphate (CDP)-DAG synthase, CDS, CDP-diacylglycerol synthetase, CDP-diacylglycerol synthase, CG7962, diacyl-glycerol-synthetase, eye-cds, winded, cdsA, CDS-diacylglycerol synthase, eye-CDS, cds" "IPR016720=Phosphatidate cytidylyltransferase, eukaryota, IPR000374=Phosphatidate cytidylyltransferase" CG7962 16-Dec-15 2015_12 "ENSDARG00000019549(LOC100002015),ENSDARG00000035577(cds2)" YBR029C(CDS1) WBGene00016384(C33H5.18) ENSXETG00000006275(CDS1) "ENSMUSG00000058793(Cds2),ENSMUSG00000029330(Cds1)" "ENSG00000101290(CDS2),ENSG00000163624(CDS1)" adult stage " adult head

, photoreceptor cell R1--8

, ocellus

" "neurophysiology defective,viable,visual behavior defective,thermotaxis behavior defective,wild-type,lethal,recessive" "photoreceptor cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,rhabdomere,eye photoreceptor cell,ommatidium,salivary gland,lipid particle | ectopic,lipid particle | ectopicppl.PP,lipid particle | ectopicelav.PU,terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0036774 mRpS26 mitochondrial ribosomal protein S26 http://flybase.net/reports/FBgn0036774.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "CG7354, MRP-S26" IPR026140=28S ribosomal protein S26 CG7354 16-Dec-15 2015_12 ENSDARG00000039719(zgc:92670) WBGene00016412(C34E10.11) ENSMUSG00000037740(Mrps26) viable FBgn0030050 CG12111 http://flybase.net/reports/FBgn0030050.html protein_coding_gene 0030246=carbohydrate binding "IPR016187=C-type lectin fold, IPR001304=C-type lectin, IPR016186=C-type lectin-like" CG12111 16-Dec-15 2015_12 "ENSDARG00000059261(LOC100333431),ENSDARG00000068178,ENSDARG00000012263(si:ch73-343l4.8),ENSDARG00000071218,ENSDARG00000025547,ENSDARG00000071219(illr2),ENSDARG00000059254(illr1),ENSDARG00000018327(illr3),ENSDARG00000025150,ENSDARG00000069322,ENSDARG00000043894,ENSDARG00000055817,ENSDARG00000029461,ENSDARG00000057091,ENSDARG00000045511,ENSDARG00000008182,ENSDARG00000032346,ENSDARG00000039636,ENSDARG00000069323,ENSDARG00000069226,ENSDARG00000026805,ENSDARG00000057090,ENSDARG00000057092,ENSDARG00000042136,ENSDARG00000070106(LOC100331932)" "ENSXETG00000000644(),ENSXETG00000021878(),ENSXETG00000000646(),ENSXETG00000026809(),ENSXETG00000023911()" "ENSMUSG00000040197(Cd209e),ENSMUSG00000040165(Cd209c),ENSMUSG00000031494(Cd209a),ENSMUSG00000065987(Cd209b),ENSMUSG00000079168(Cd209g),ENSMUSG00000074491(Clec4g),ENSMUSG00000030142(Clec4e),ENSMUSG00000051906(Cd209f),ENSMUSG00000071158(Gm156),ENSMUSG00000030158(Clec12b)" "ENSG00000166527(CLEC4D),ENSG00000205846(CLEC6A),ENSG00000166523(CLEC4E),ENSG00000141505(ASGR1)" viable FBgn0087013 Karyë_3 Karyopherin ë_ 3 http://flybase.net/reports/FBgn0087013.html "FBgn0011341, FBgn0025493" protein_coding_gene 0008320=protein transmembrane transporter activity 0006606=protein import into nucleus "0005643=nuclear pore, 0005829=cytosol, 0005875=microtubule associated complex" "Kary-beta3, Karyopherin beta, CG1059, Karyopherin beta 3, l(3)82CDd, lethal (3) 82CDd, l(3)j7E8, unnamed, l(3)j3A4, karyopherin-beta3, Karbeta3, Karybeta3" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR000357=HEAT repeat, IPR021133=HEAT, type 2" CG1059 16-Dec-15 2015_12 ENSDARG00000040245(kpnb3) YMR308C(PSE1) WBGene00002077(imb-3) ENSXETG00000023496(ranbp5) "ENSMUSG00000030662(Ipo5),ENSMUSG00000074909(Ranbp6)" "ENSG00000065150(IPO5),ENSG00000137040(RANBP6)" DRSC12355 IE 5.159312348 -0.149857756 4.402984192 -0.790337049 -0.769482702 -0.018088016 FBgn0036544 sff sugar-free frosting http://flybase.net/reports/FBgn0036544.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0006487=protein N-linked glycosylation, 0007528=neuromuscular junction development, 0006468=protein phosphorylation" "0005737=cytoplasm, 0005634=nucleus" "CG6114, SNF1-related" "IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG6114 16-Dec-15 2015_12 WBGene00004719(sad-1) "ENSXETG00000004614(BRSK2),ENSXETG00000022924(BRSK1)" "ENSMUSG00000035390(Brsk1),ENSMUSG00000053046(Brsk2)" "ENSG00000160469(BRSK1),ENSG00000174672(BRSK2)" "partially lethal - majority live,gravitaxis defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,embryonic/larval hemocyte | third instar larval stage" FBgn0036111 Aps Aps http://flybase.net/reports/FBgn0036111.html FBgn0062133 protein_coding_gene 0008486=diphosphoinositol-polyphosphate diphosphatase activity "0009117=nucleotide metabolic process, 0043647=inositol phosphate metabolic process" "0005634=nucleus, 0005737=cytoplasm" "CG6391, anon-WO0118547.266" "IPR015797=NUDIX hydrolase domain-like, IPR020084=NUDIX hydrolase, conserved site, IPR000086=NUDIX hydrolase domain" CG6391 16-Dec-15 2015_12 "ENSDARG00000057767(nudt4),ENSDARG00000016256(nudt3a),ENSDARG00000045878(zgc:101062)" YOR163W(DDP1) WBGene00022366(Y92H12BL.5) ENSXETG00000026585(nudt4) "ENSMUSG00000024213(Nudt3),ENSMUSG00000020029(Nudt4),ENSMUSG00000073293(Nudt10),ENSMUSG00000073295(Nudt11)" "ENSG00000112664(NUDT3),ENSG00000173598(NUDT4),ENSG00000196368(NUDT11),ENSG00000122824(NUDT10)" viable FBgn0039091 CG10182 http://flybase.net/reports/FBgn0039091.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" "IPR006621=Nose resistant-to-fluoxetine protein, N-terminal, IPR002656=Acyltransferase 3" CG10182 16-Dec-15 2015_12 "WBGene00007835(oac-7),WBGene00009488(oac-20),WBGene00007829(oac-5),WBGene00007833(oac-6),WBGene00009230(oac-18),WBGene00008602(oac-14),WBGene00018708(oac-32),WBGene00018707(oac-31),WBGene00012308(oac-53),WBGene00007361(oac-3),WBGene00009972(oac-33),WBGene00020864(oac-50)" viable FBgn0051373 CG31373 http://flybase.net/reports/FBgn0051373.html FBgn0037825 protein_coding_gene "0042586=peptide deformylase activity, 0005506=iron ion binding" "PDF, CG6482" "IPR023635=Peptide deformylase, IPR000181=Formylmethionine deformylase" CG31373 16-Dec-15 2015_12 ENSDARG00000013950(zgc:114141) ENSXETG00000022729(pdf) ENSMUSG00000078931 ENSG00000157312 lethal FBgn0086604 CG12484 http://flybase.net/reports/FBgn0086604.html "FBgn0053041, FBgn0050143, FBgn0034508, FBan0030143" protein_coding_gene 0046331=lateral inhibition 0005886=plasma membrane "CT32777, 12484, CG30143, CG33041" "IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR003961=Fibronectin type III, IPR013106=Immunoglobulin V-set domain, IPR013162=CD80-like, immunoglobulin C2-set, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold" CG12484 16-Dec-15 2015_12 "ENSXETG00000001127(),ENSXETG00000013054(),ENSXETG00000001171()" "viable,visible" "chaeta,supernumerary" FBgn0039629 CG11842 http://flybase.net/reports/FBgn0039629.html protein_coding_gene 0004252=serine-type endopeptidase activity "0006508=proteolysis, 0034976=response to endoplasmic reticulum stress" SP68 "IPR001254=Serine proteases, trypsin domain, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type" CG11842 16-Dec-15 2015_12 "ENSXETG00000016792(plat),ENSXETG00000007245(F12),ENSXETG00000005495(HGFAC),ENSXETG00000018616(HABP2),ENSXETG00000010002(),ENSXETG00000004035(PRSS12)" "ENSMUSG00000025075(Habp2),ENSMUSG00000029102(Hgfac),ENSMUSG00000031538(Plat),ENSMUSG00000021822(Plau),ENSMUSG00000021492(F12),ENSMUSG00000027978(Prss12)" "viable,fertile" FBgn0032059 PrBP Prenyl-binding protein http://flybase.net/reports/FBgn0032059.html protein_coding_gene "0047555=3',5'-cyclic-GMP phosphodiesterase activity" "0007601=visual perception, 0016319=mushroom body development" 0005634=nucleus "prenyl-binding protein, DmPrBP/delta, CG9296, DmPrBP" "IPR014756=Immunoglobulin E-set, IPR017287=Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit, IPR008015=GMP phosphodiesterase, delta subunit" CG9296 16-Dec-15 2015_12 ENSDARG00000032518(LOC100332842) WBGene00003966(pdl-1) ENSXETG00000022759(PDE6D) ENSMUSG00000026239(Pde6d) ENSG00000156973(PDE6D) "neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "optic lobe,eye,adult mushroom body,mesothoracic tergum" DRSC25862 IK 0.572761068 1.731020089 -0.560945528 0.873811422 1.102042542 1.656097109 FBgn0038358 CG4525 http://flybase.net/reports/FBgn0038358.html protein_coding_gene 0042384=cilium assembly "0030992=intraciliary transport particle B, 0005929=cilium" TTC26 "IPR030511=Tetratricopeptide repeat protein 26, IPR011990=Tetratricopeptide-like helical domain" CG4525 16-Dec-15 2015_12 ENSDARG00000012039(ttc26) WBGene00001129(dyf-13) ENSMUSG00000056832(Ttc26) ENSG00000105948(TTC26) viable FBgn0039557 CG12259 http://flybase.net/reports/FBgn0039557.html protein_coding_gene 0044822=poly(A) RNA binding 0022008=neurogenesis 0005654=nucleoplasm IPR007005=XAP5 protein CG12259 16-Dec-15 2015_12 ENSDARG00000024895(fam50a) WBGene00008143(C47E8.4) ENSXETG00000003375(fam50a) "ENSMUSG00000001962(Fam50a),ENSMUSG00000038246" "ENSG00000071859(FAM50A),ENSG00000145945(FAM50B)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0010548 Aldh-III Aldehyde dehydrogenase type III http://flybase.net/reports/FBgn0010548.html FBgn0033180 protein_coding_gene "0004030=aldehyde dehydrogenase [NAD(P)+] activity, 0016620=oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" "0006081=cellular aldehyde metabolic process, 0055114=oxidation-reduction process" 0005811=lipid particle "ALDH, Fatty Aldehyde Dehydrogenase, FALDH, l(2)03610, ALDH-III, CT41571, CG11140, Fatty aldehyde dehydrogenase, Dhap" "IPR016160=Aldehyde dehydrogenase, cysteine active site, IPR012394=Aldehyde dehydrogenase NAD(P)-dependent, IPR016163=Aldehyde dehydrogenase, C-terminal, IPR029510=Aldehyde dehydrogenase, glutamic acid active site, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR015590=Aldehyde dehydrogenase domain, IPR016161=Aldehyde/histidinol dehydrogenase" CG11140 16-Dec-15 2015_12 "ENSDARG00000029381(zgc:103715),ENSDARG00000028259(aldh3a2)" YMR110C(HFD1) "WBGene00000110(alh-4),WBGene00000111(alh-5)" ENSXETG00000013484(TTpA004m18.1) "ENSMUSG00000024885(Aldh3b1),ENSMUSG00000010025(Aldh3a2)" "ENSG00000006534,ENSG00000132746(ALDH3B2),ENSG00000072210(ALDH3A2)" "partially lethal - majority die,lethal,recessive,chemical sensitive,behavior defective,viable,partially lethal,conditional,developmental rate defective" crystal cell FBgn0001494 l(1)10Bh lethal (1) 10Bh http://flybase.net/reports/FBgn0001494.html gene "l(1)MSV22, l(1)MSV12, l(1)GLM20M21, locus 21, l(1)GLM21, 10Bh, l(1)G21" 16-Dec-15 2015_12 "male sterile,female sterile,lethal,partially,female fertile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "primary spermatocyte cyst,spermatid,major mitochondrial derivative,minor mitochondrial derivative" FBgn0036839 CG18136 http://flybase.net/reports/FBgn0036839.html protein_coding_gene "0008270=zinc ion binding, 0042826=histone deacetylase binding" 0010629=negative regulation of gene expression "IPR001214=SET domain, IPR002893=Zinc finger, MYND-type" CG18136 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" FBgn0004545 l(4)102CDp lethal (4) 102CDp http://flybase.net/reports/FBgn0004545.html gene "l(4)CDp, l(4)31" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069222 gl(2R)243-17 gl(2R)243-17 http://flybase.net/reports/FBgn0069222.html gene 0007379=segment specification 16-Dec-15 2015_12 "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0033901 O-fut1 O-fucosyltransferase 1 http://flybase.net/reports/FBgn0033901.html FBgn0065211 protein_coding_gene "0046922=peptide-O-fucosyltransferase activity, 0005112=Notch binding, 0008417=fucosyltransferase activity" "0045746=negative regulation of Notch signaling pathway, 0008593=regulation of Notch signaling pathway, 0006897=endocytosis, 0016337=single organismal cell-cell adhesion, 0006493=protein O-linked glycosylation, 0030163=protein catabolic process, 0045747=positive regulation of Notch signaling pathway, 0046331=lateral inhibition, 0007399=nervous system development" "0005783=endoplasmic reticulum, 0030173=integral component of Golgi membrane, 0005794=Golgi apparatus, 0031410=cytoplasmic vesicle" "OFUT1, O-fucosyltransferase, l(2)SH2 2260, Ofut1, Ofut-1, OFut1, 4R6, CG12366, Neurotic, neurotic, O-FUT1, nti, l(2)SH2260, ntc, AAF58290.1, O-fut, O-fucosyl transferase" IPR019378=GDP-fucose protein O-fucosyltransferase CG12366 16-Dec-15 2015_12 ENSDARG00000008953(pofut1) WBGene00015793(C15C7.7) ENSXETG00000016634(pofut1) ENSMUSG00000046020(Pofut1) ENSG00000101346(POFUT1) " larval stage , embryonic stage | stage 3-11 , embryonic stage | stage 13 , embryonic stage | stage 1-12 " " ventral thoracic disc

uniform , organism

, lymph gland

, dorsal mesothoracic disc

uniform , germline cell

, eye disc

, antennal disc

uniform , central nervous system

, dorsal metathoracic disc

uniform ,

ubiquitous " "neuroanatomy defective,viable,fertile,lethal,recessive,visible,somatic clone,lethal - all die before end of first instar larval stage,germline clone,maternal effect,some die during first instar larval stage,neurogenic phenotype" "embryonic/larval optic lobe,wing,somatic clone,wing vein,macrochaeta,scutellar bristle,neuron,germline clone,non-rescuable maternal effect,wing margin,intestinal stem cell,supernumerary,eye,leg,distal,mesothoracic tergum & microchaetaap-md544,mesothoracic tergum & eo neuronap-md544,mesothoracic tergum & thecogen cellap-md544,microchaeta,S2 cell-line,chaeta" FBgn0003559 su(f) suppressor of forked http://flybase.net/reports/FBgn0003559.html "FBgn0028293, FBan0017170" protein_coding_gene "0006397=mRNA processing, 0016070=RNA metabolic process, 0006379=mRNA cleavage, 1903220=positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity" "0005848=mRNA cleavage stimulating factor complex, 0005634=nucleus, 0005847=mRNA cleavage and polyadenylation specificity factor complex" "CstF-77, 3DES, l(1)3DES, Su(f), section 28, l(1)X1, Cstf77, EC235, su[+]-f, 29, 28, l3DES, CstF77, l(1)su(f), l(1)X3, 3-DES, su-f, l(1)R-9-18, SU-f, section 29, CG17170, R-9-18, l(1)G0393, lethal3Des, 19, section 19, l(1)20Eb, l(1)EC235, R9-18" "IPR003107=HAT (Half-A-TPR) repeat, IPR008847=Suppressor of forked" CG17170 16-Dec-15 2015_12 ENSDARG00000018904(cstf3) YMR061W(RNA14) WBGene00006307(suf-1) ENSXETG00000021399() ENSMUSG00000027176(Cstf3) ENSG00000176102(CSTF3) embryonic stage -- adult stage "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,cell lethal,germline clone,wild-type,visible,heat sensitive,body color defective,male,male fertile,female sterile,mating defective,hypoactive,female,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death" "adult thorax,heat sensitive,wing,macrochaeta,larval brain & mitotic cell cycle,eye,head,gena,leg,prothoracic leg,scutum,ovariole,follicle cell,microchaeta,anterior,dorsal,interfollicle cell,germline cyst,germline cell,female,egg chamber,imaginal disc,embryonic/larval brain,embryonic/larval optic lobe,nuclear chromosome & larval brain | conditional ts,mitotic cell cycle & larval brain | conditional ts,imaginal disc & mitotic metaphase | conditional ts,imaginal disc & spindle | conditional ts,imaginal disc & metaphase & condensed nuclear chromosome | conditional ts,eye-antennal disc,antennal disc" DRSC20907 I 0.157504898 1.619294608 -0.372092803 1.491350254 -0.026694376 0.00066504 FBgn0002809 ms(1)413 male sterile (1) 413 http://flybase.net/reports/FBgn0002809.html gene "ms(1)682, ms(1)RD11" 16-Dec-15 2015_12 "male sterile,meiotic cell cycle defective,male,behavior defective" "meiotic cell cycle | male,spermatocyte,spermatid,Nebenkern,Nebenkern derivative,spermatid & centriole" FBgn0003880 tu(3)be benign tumor in chromosome 3 http://flybase.net/reports/FBgn0003880.html FBgn0000169 gene "tumor(3)be, benign, be, be-3" 16-Dec-15 2015_12 "viable,melanotic mass phenotype" FBgn0032744 Ttc19 Tetratricopeptide repeat domain 19 http://flybase.net/reports/FBgn0032744.html protein_coding_gene "0097033=mitochondrial respiratory chain complex III biogenesis, 0007630=jump response, 0071632=optomotor response" "cg15173, CG15173, TTC19" "IPR013026=Tetratricopeptide repeat-containing domain, IPR011990=Tetratricopeptide-like helical domain" CG15173 16-Dec-15 2015_12 WBGene00013217(ddl-3) ENSXETG00000022441(TTC19) ENSMUSG00000042298(Ttc19) ENSG00000011295(TTC19) "viable,fertile,short lived,semi-sterile,bang sensitive,locomotor behavior defective,visual behavior defective" FBgn0021816 l(2)k16406 lethal (2) k16406 http://flybase.net/reports/FBgn0021816.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0000940 fs(2)A10 female sterile (2) A10 http://flybase.net/reports/FBgn0000940.html gene 16-Dec-15 2015_12 "female sterile,recessive" female reproductive system FBgn0002331 l(3)87Ad lethal (3) 87Ad http://flybase.net/reports/FBgn0002331.html gene "ck11, l(3)ck11" 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065650 l(2)SH0734 lethal (2) SH0734 http://flybase.net/reports/FBgn0065650.html gene l(2)SH2 0734 16-Dec-15 2015_12 "lethal,recessive" FBgn0015269 Nf1 Neurofibromin 1 http://flybase.net/reports/FBgn0015269.html protein_coding_gene 0005096=GTPase activator activity "0007265=Ras protein signal transduction, 0040018=positive regulation of multicellular organism growth, 0008355=olfactory learning, 0007614=short-term memory, 0043547=positive regulation of GTPase activity, 0006979=response to oxidative stress, 0046580=negative regulation of Ras protein signal transduction, 0008340=determination of adult lifespan, 0019933=cAMP-mediated signaling, 0040014=regulation of multicellular organism growth, 0045475=locomotor rhythm, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0042066=perineurial glial growth, 0009408=response to heat, 0007616=long-term memory, 0046578=regulation of Ras protein signal transduction, 0045762=positive regulation of adenylate cyclase activity" "0005737=cytoplasm, 0031235=intrinsic component of the cytoplasmic side of the plasma membrane" "Neurofibromin 1, neurofibromatosis 1, Neurofibromin, NF1, Neurofibromatosis-1, dNF1, NF-1, Neurofibromatosis 1, CG8318, neurofibramatosis-1, Nf-1, neurofibromin, Neurofibromatosis Factor 1, neurofibromatosis type 1, nf1, dNf1" "IPR028553=Neurofibromin, IPR008936=Rho GTPase activation protein, IPR001251=CRAL-TRIO lipid binding domain, IPR016024=Armadillo-type fold, IPR001936=Ras GTPase-activating protein" CG8318 16-Dec-15 2015_12 "ENSDARG00000004184(nf1a),ENSDARG00000012982(nf1b)" "YOL081W(IRA2),YBR140C(IRA1)" ENSMUSG00000020716(Nf1) ENSG00000196712(NF1) " larval stage , embryonic stage " imaginal disc

" embryonic stage , larval stage " imaginal disc

"viable,fertile,small body,male limited,memory defective,locomotor rhythm defective,learning defective,behavior defective,short lived,heat stress response defective,heat sensitive,oxidative stress response defective,neuroanatomy defective,long lived,wild-type,semi-sterile,size defective,neurophysiology defective,dominant,decreased cell size" "surface associated glial cell,eye photoreceptor cell,neuromuscular junction | larval stage,pupa,NMJ bouton,supernumerary,heart primordium,wing,wing disc" FBgn0039380 CG5890 http://flybase.net/reports/FBgn0039380.html protein_coding_gene 0005509=calcium ion binding "0048190=wing disc dorsal/ventral pattern formation, 0048812=neuron projection morphogenesis" "IPR028846=Recoverin family, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site" CG5890 16-Dec-15 2015_12 "ENSDARG00000034808(kcnip1b),ENSDARG00000022109(kcnip1a),ENSDARG00000043993,ENSDARG00000034229(kcnip3l),ENSDARG00000017880(kcnip3),ENSDARG00000037256" "ENSXETG00000018293(KCNIP1),ENSXETG00000014462(KCNIP2),ENSXETG00000004341(KCNIP3),ENSXETG00000027346(KCNIP4)" "ENSMUSG00000053519(Kcnip1),ENSMUSG00000029088(Kcnip4),ENSMUSG00000025221(Kcnip2),ENSMUSG00000079056(Kcnip3)" "ENSG00000182132(KCNIP1),ENSG00000185774(KCNIP4),ENSG00000120049(KCNIP2),ENSG00000115041(KCNIP3)" viable DRSC15909 K -0.064977609 -0.900281667 -0.473872207 0.458190839 1.852230101 -0.560590616 FBgn0039637 CG11880 http://flybase.net/reports/FBgn0039637.html protein_coding_gene IPR007603=Choline transporter-like CG11880 16-Dec-15 2015_12 "ENSDARG00000057419(slc44a5b),ENSDARG00000017398(slc44a5a),ENSDARG00000037059,ENSDARG00000017554" WBGene00018037(chtl-1) "ENSXETG00000010924(SLC44A4),ENSXETG00000002987(SLC44A5),ENSXETG00000011650(SLC44A2)" "ENSMUSG00000007034(Slc44a4),ENSMUSG00000057193(Slc44a2),ENSMUSG00000028360(Slc44a5)" "ENSG00000206378,ENSG00000206269,ENSG00000204385(SLC44A4),ENSG00000129353(SLC44A2),ENSG00000137968(SLC44A5)" viable FBgn0034314 nopo no poles http://flybase.net/reports/FBgn0034314.html protein_coding_gene "0070182=DNA polymerase binding, 0004842=ubiquitin-protein transferase activity, 0031624=ubiquitin conjugating enzyme binding, 0008270=zinc ion binding" "0008219=cell death, 0006952=defense response, 0016567=protein ubiquitination, 0051276=chromosome organization, 0045977=positive regulation of mitotic cell cycle, embryonic, 0007165=signal transduction" 0005634=nucleus "CG5140, TRIP, Nopo, NOPO" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR011016=Zinc finger, RING-CH-type, IPR001841=Zinc finger, RING-type" CG5140 16-Dec-15 2015_12 ENSDARG00000011262 WBGene00015194(B0432.13) ENSXETG00000005959(traip) ENSMUSG00000032586(Traip) ENSG00000183763(TRAIP) "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal - all die during embryonic stage,maternal effect,viable,increased cell death,partially lethal,majority die during embryonic stage,developmental rate defective,heat sensitive" "centrosome | non-rescuable maternal effect,spindle | non-rescuable maternal effect,mitotic spindle | maternal effect,eye,wing margin" FBgn0262614 pyd polychaetoid http://flybase.net/reports/FBgn0262614.html "FBgn0003177, FBgn0010330, FBgn0037639, FBgn0037641, FBgn0037642, FBgn0040533, FBgn0051349, FBgn0037640" protein_coding_gene "0050699=WW domain binding, 0004385=guanylate kinase activity, 0050839=cell adhesion molecule binding, 0031625=ubiquitin protein ligase binding" "0035156=fusion cell fate specification, 0030155=regulation of cell adhesion, 0016476=regulation of embryonic cell shape, 0007254=JNK cascade, 0007424=open tracheal system development, 0001745=compound eye morphogenesis, 0072697=protein localization to cell cortex, 0048812=neuron projection morphogenesis, 0016337=single organismal cell-cell adhesion, 0007219=Notch signaling pathway, 0036059=nephrocyte diaphragm assembly, 0035147=branch fusion, open tracheal system, 0022416=chaeta development, 0046328=regulation of JNK cascade, 0007163=establishment or maintenance of cell polarity, 0046331=lateral inhibition, 0060439=trachea morphogenesis, 0045176=apical protein localization, 0035220=wing disc development, 0008258=head involution, 0007391=dorsal closure" "0005912=adherens junction, 0016323=basolateral plasma membrane, 0045177=apical part of cell, 0005917=nephrocyte diaphragm, 0005886=plasma membrane, 0005938=cell cortex, 0030424=axon, 0005913=cell-cell adherens junction" "polychaetoid, xvt, CG31349, pyd(Z01), tamou, Pyd, tam, ZO-1, Pyd/ZO-1, ZO1, CG9731, CG11782, CG43140, CG9729, failed fusions, Polychaetoid, dzo-1, CG11962, Tamou, Pch, CG12409, extra verticals, DZO-1, CT36877, CG9763" "IPR011511=Variant SH3 domain, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR001478=PDZ domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008144=Guanylate kinase-like domain, IPR001452=SH3 domain, IPR000906=ZU5 domain" CG43140 16-Dec-15 2015_12 WBGene00013683(zoo-1) ENSXETG00000020296() ENSMUSG00000024812(Tjp2) "ENSG00000104067(TJP1),ENSG00000119139(TJP2)" " embryonic stage -- adult stage , larval stage && pupal stage , larval stage | third instar " dorsal mesothoracic disc

" larval stage && pupal stage , larval stage | third instar , embryonic stage " dorsal mesothoracic disc

DRSC14509 K 0.087400407 0.184327963 0.014396083 0.047489705 0.231123254 1.516905631 FBgn0265274 Inx3 Innexin 3 http://flybase.net/reports/FBgn0265274.html "FBgn0028373, FBgn0039606, FBgn0025230" protein_coding_gene 0005243=gap junction channel activity "0007391=dorsal closure, 0010496=intercellular transport" "0016328=lateral plasma membrane, 0005921=gap junction, 0005886=plasma membrane" "INX-3, Ix3, FBpp0084719, Innexin-3, anon-fast-evolving-2B11, innexin 3, inx-3, innexin3, anon-EST:fe2B11, Dm-inx3, CG1448, Innexin, inx3" IPR000990=Innexin CG1448 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" DRSC14857 I 0.538790899 1.6226549 0.158624786 1.061106873 0.11127459 -0.148987143 FBgn0051617 His1:CG31617 His1:CG31617 http://flybase.net/reports/FBgn0051617.html protein_coding_gene 0003677=DNA binding "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG31617 "IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain" CG31617 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" DRSC21266 I 1.674501497 1.169573763 1.18066883 -0.601981771 -0.915227058 0.236375266 FBgn0010812 unc-45 http://flybase.net/reports/FBgn0010812.html FBgn0037545 protein_coding_gene "0050829=defense response to Gram-negative bacterium, 0034605=cellular response to heat, 0061077=chaperone-mediated protein folding, 0031034=myosin filament assembly, 0007525=somatic muscle development, 0045824=negative regulation of innate immune response" "DmUNC-45, DmUnc-45, Translocase of outer membrane 34, Tom34, dunc-45, l(3)03692, dUNC-45, lincRNA.721, CG2708" "IPR024660=UNC-45/Cro1/She4, central domain, IPR000225=Armadillo, IPR011990=Tetratricopeptide-like helical domain, IPR011989=Armadillo-like helical, IPR013105=Tetratricopeptide repeat 2, IPR019734=Tetratricopeptide repeat, IPR016024=Armadillo-type fold, IPR013026=Tetratricopeptide repeat-containing domain" CG2708 16-Dec-15 2015_12 "ENSDARG00000008433(unc45b),ENSDARG00000003546(unc45a)" WBGene00006781(unc-45) "ENSXETG00000013482(cmya4),ENSXETG00000015452(UNC45A)" "ENSMUSG00000030533(Unc45a),ENSMUSG00000018845(Unc45b)" "ENSG00000141161(UNC45B),ENSG00000140553(UNC45A)" "short lived,lethal,recessive,viable,fertile,lethal - all die before end of larval stage,some die during third instar larval stage" "myofibril,embryonic somatic muscle,adult heart,adult heart chamber 1,adult heart chamber 2,myofibrilHCH.Hand,embryonic/larval heart | P-stage,embryonic/larval heart | third instar larval stage" FBgn0085242 CG34213 http://flybase.net/reports/FBgn0085242.html protein_coding_gene IPR008979=Galactose-binding domain-like CG34213 16-Dec-15 2015_12 ENSDARG00000056162(zgc:136330) ENSXETG00000026881(NR2C2AP) ENSMUSG00000071078(Nr2c2ap) ENSG00000184162(NR2C2AP) FBgn0037653 CG11982 http://flybase.net/reports/FBgn0037653.html protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0008270=zinc ion binding" 0051865=protein autoubiquitination "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG11982 16-Dec-15 2015_12 ENSDARG00000062450(zgc:158455) YDR143C(SAN1) WBGene00021842(Y54E10BR.3) "ENSXETG00000018682(RNF115),ENSXETG00000006543(rnf126)" "ENSMUSG00000028098(Rnf115),ENSMUSG00000035890(Rnf126)" "ENSG00000070423(RNF126),ENSG00000121848(RNF115)" viable FBgn0259244 CG42342 http://flybase.net/reports/FBgn0259244.html "FBgn0038441, FBgn0250909, FBgn0038442, FBgn0038443, FBgn0038444" protein_coding_gene "CG42243, CG14888, CG14890, CG11769, CG14889" IPR008160=Collagen triple helix repeat CG42342 16-Dec-15 2015_12 WBGene00000674(col-99) "ENSXETG00000016183(),ENSXETG00000022341(),ENSXETG00000021972(COL27A1),ENSXETG00000017926(COL9A1),ENSXETG00000010783(COL3A1),ENSXETG00000020318(COL1A2),ENSXETG00000001565(),ENSXETG00000010784(COL5A2),ENSXETG00000004773(COL9A2),ENSXETG00000020448(),ENSXETG00000006108(COL9A3),ENSXETG00000003541()" ENSMUSG00000058806(Col13a1) ENSG00000197467(COL13A1) DRSC15012 IEK 1.640519945 0.86783679 1.981476138 -0.092427495 1.036820535 1.657364884 FBgn0034876 wmd wing morphogenesis defect http://flybase.net/reports/FBgn0034876.html protein_coding_gene 0005102=receptor binding 0007476=imaginal disc-derived wing morphogenesis 0005875=microtubule associated complex "CG3957, pterodactyl, CG3957/wmd, Wing morphogenesis defect, WMD, pter" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR020472=G-protein beta WD-40 repeat" CG3957 16-Dec-15 2015_12 ENSDARG00000007405(strap) ENSXETG00000022527(STRAP) ENSMUSG00000030224(Strap) ENSG00000023734(STRAP) "visible,dominant,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,viable" "wing,dorsal appendage,drug conditional,wing vein" FBgn0034459 CG16716 http://flybase.net/reports/FBgn0034459.html FBgn0044605 protein_coding_gene 0004835=tubulin-tyrosine ligase activity 0006464=cellular protein modification process anon-WO0140519.27 IPR004344=Tubulin-tyrosine ligase/Tubulin polyglutamylase CG16716 16-Dec-15 2015_12 ENSDARG00000054023(ttll6) ENSXETG00000027619(TTLL13) "ENSMUSG00000045467(Ttll13),ENSMUSG00000038756(Ttll6)" "ENSG00000170703(TTLL6),ENSG00000213471(TTLL13)" viable FBgn0028931 CG16863 http://flybase.net/reports/FBgn0028931.html protein_coding_gene 0003677=DNA binding "DS00797.6, BG:DS00797.6" "IPR012337=Ribonuclease H-like domain, IPR015880=Zinc finger, C2H2-like, IPR003656=Zinc finger, BED-type" CG16863 16-Dec-15 2015_12 "ENSDARG00000056115,ENSDARG00000070207,ENSDARG00000052444" "WBGene00010704(K09A11.1),WBGene00015662(C10A4.1)" "ENSXETG00000017638(),ENSXETG00000002916()" ENSG00000214717(ZBED1) viable FBgn0011706 rpr reaper http://flybase.net/reports/FBgn0011706.html FBgn0045867 protein_coding_gene "0042803=protein homodimerization activity, 0031625=ubiquitin protein ligase binding, 0005543=phospholipid binding, 0031624=ubiquitin conjugating enzyme binding" "0042176=regulation of protein catabolic process, 0006915=apoptotic process, 0048803=imaginal disc-derived male genitalia morphogenesis, 0008627=intrinsic apoptotic signaling pathway in response to osmotic stress, 0008219=cell death, 0035071=salivary gland cell autophagic cell death, 0097190=apoptotic signaling pathway, 2001056=positive regulation of cysteine-type endopeptidase activity, 0012501=programmed cell death, 0043524=negative regulation of neuron apoptotic process, 0035193=larval central nervous system remodeling, 2000060=positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0071480=cellular response to gamma radiation, 0035096=larval midgut cell programmed cell death, 0031398=positive regulation of protein ubiquitination, 0008630=intrinsic apoptotic signaling pathway in response to DNA damage, 0071479=cellular response to ionizing radiation, 0045476=nurse cell apoptotic process, 2001272=positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis" "0005739=mitochondrion, 0005741=mitochondrial outer membrane, 0005737=cytoplasm, 0000502=proteasome complex" "Reaper, anon-WO0162936.19, Rpr, REAPER, unnamed, RPR, reaper, rp, Reaper L, CG4319" CG4319 16-Dec-15 2015_12 " pupal stage , embryonic stage | stage 12 " " salivary gland

, organism | segmentally repeated

" "decreased cell death,increased cell death,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,visible,lethal,dominant,cell death defective,somatic clone,behavior defective,recessive,partially lethal - majority die,majority die during pupal stage,neuroanatomy defective,chemical sensitive,viable,small body,developmental rate defective,decreased cell number,decreased cell size,aging defective,long lived,female fertile,reduced,heat stress response defective,fertile,chemosensitive behavior defective,mating defective,locomotor behavior defective,conditional,sleep defective,lethal - all die before end of larval stage,some die during larval stage,feeding behavior defective,polyphasic,eclosion rhythm defective,lethal - all die before end of embryonic stage,some die during embryonic stage,drug conditional,flight defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female,short lived,temperature conditional,size defective,majority die during pharate adult stage,locomotor rhythm defective,neurophysiology defective,courtship behavior defective,male,radiation resistant,cell non-autonomous,tetracycline conditional,cell autonomous" "eye,embryonic/larval salivary gland,heat sensitive,dMP2 neuron,MP1 neuron,wing,embryo,ommatidium,somatic clone,interommatidial bristle,eye disc,eye photoreceptor cell,peptidergic neuron | third instar larval stage,follicle cell,polar primary spermatocyte,corpus cardiacum,dorsomedial neurosecretory cell,oocyte,neurosecretory neuron,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial ligament cell & stage 16 embryorepo,lch5 ligament attachment cell | embryonic stage 16,lipid droplet & larval fat bodysal.BO,embryonic/larval oenocyte,neuron,adult head,pharate adult,leg,subesophageal ganglion neuron,thoracico-abdominal ganglion,embryonic/larval midgut,adult midgut precursor cell,alula,axillary cell,adult brain,wing disc | third instar larval stage,head | pharate adult stage,plasmatocyte | third instar larval stage,embryonic/larval lymph gland | first instar larval stage,adult dorsal vessel,embryonic cardioblast | embryonic stage 15,embryonic/larval salivary gland | embryonic stage 17,amnioserosa,nurse cell,follicle cell & nucleus | somatic clone,nurse cell & nucleus | somatic clone,nurse cell ring canal,nurse cell & cytoskeleton | somatic clone,macrochaeta & scutellum-537.4,macrochaeta & mesothoracic tergum-537.4,macrochaeta & tergum-537.4,border follicle cell,larval hindgut & ectoderm455.2,hindgut visceral muscle primordium,U neuron,pCC neuron,RP2 motor neuron,aCC neuron,wing vein,ectopic,wing vein L2,wing vein L4,wing vein L5,large sensillum basiconicum of antennal segment 3 & olfactory neuronOr22a.8197,large sensillum basiconicum of antennal segment 3 & olfactory neuronOr22b.10287,olfactory neuron & maxillary palp sense organOr42a.PG,olfactory neuron & maxillary palp sense organOr71a.PG,olfactory neuron & maxillary palp sense organ,olfactory neuron & maxillary palp sense organOr33c.PG,olfactory neuron & maxillary palp sense organOr46a.PG,olfactory sensory organ,sensillum basiconicum of antennal segment 3,maxillary palp sensillum basiconicum,eo dendrite & sensillum basiconicum of antennal segment 3Obp28a.PP,abdominal dorsal/lateral multidendritic neuron,neuron | larval stage,LNv neuron,Pdf neuron,ventral midline | embryonic stage,midline glial cell,centripetally migrating follicle cell,photoreceptor cell R5,embryonic/larval trachea,dorsal,adult cuticle,EH neurosecretory neuron,embryonic/larval mouth,Tv neuron,outer photoreceptor cell,macrochaeta,neuropil glial sheath | late embryonic stage,embryonic/larval brain | late embryonic stage,glial cell | larval stage,wing disc,rhabdomere R7,tetracycline conditional,male genitalia,conditional,retina,cell autonomous" DRSC11390 IE 1.826927148 0.763723667 1.806261988 -1.144980326 -0.072482058 0.22588269 FBgn0028978 trbl tribbles http://flybase.net/reports/FBgn0028978.html FBgn0036983 protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0042803=protein homodimerization activity, 0005524=ATP binding, 0046982=protein heterodimerization activity" "0006468=protein phosphorylation, 0051726=regulation of cell cycle, 0007370=ventral furrow formation, 0007369=gastrulation, 0045839=negative regulation of mitotic nuclear division, 2000060=positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process" 0005634=nucleus "trb, CG5408, Trbl, unnamed" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR024104=Pseudokinase tribbles family/serine-threonine-protein kinase 40" CG5408 16-Dec-15 2015_12 "ENSDARG00000016200(trib3),ENSDARG00000068179" "ENSXETG00000017499(TRIB1),ENSXETG00000027887(Trib2)" "ENSMUSG00000020601(Trib2),ENSMUSG00000032501(Trib1),ENSMUSG00000032715(Trib3)" "ENSG00000071575(TRIB2),ENSG00000173334(TRIB1),ENSG00000101255(TRIB3)" "partially lethal - majority die,lethal,partially lethal,visible,partially lethal - majority live,partially,recessive,mitotic cell cycle defective,wild-type,memory defective,polyphasic,female sterile,increased cell size,decreased cell number,viable" "ovary,border follicle cell,crossvein,wing,posterior compartment,macrochaeta,oocyte,cystocyte,mitotic domain 1,mitotic domain 2,mitotic domain 3,gastrula embryo,mesoderm anlage,trichogen cell,tormogen cell,mitotic domain 10,ventral furrow,mitotic cell cycle[-],spermatogonium,germline cyst,ectopic,egg chamber,mitotic cell cycle,eye,interommatidial bristle,wing margin,wing disc,external sensory organ precursor cell I,nurse cell,spermatogonial cyst" DRSC11901 K -0.332280978 -0.16868384 0.501439725 0.07404055 0.358122048 -2.302610888 FBgn0000237 bul bulge http://flybase.net/reports/FBgn0000237.html gene "0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0048749=compound eye development" "bumpy, bp" 16-Dec-15 2015_12 "visible,recessive,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,male fertile,female semi-sterile,lethal,dominant,female fertile,flightless" "ommatidium,wing,embryonic/larval glial cell,lens,pigment cell,eye & macrochaeta,eye" FBgn0001748 l(1)HM20 lethal (1) HM20 http://flybase.net/reports/FBgn0001748.html gene 16-Dec-15 2015_12 "lethal,recessive,cold sensitive,female sterile,visible" "macrochaeta,adult abdomen" FBgn0034528 CG11180 http://flybase.net/reports/FBgn0034528.html protein_coding_gene 0003676=nucleic acid binding 0022008=neurogenesis IPR000467=G-patch domain CG11180 16-Dec-15 2015_12 ENSDARG00000023532(pinx1) YGR280C(PXR1) WBGene00011966(T23G7.3) ENSXETG00000000688(pinx1) ENSMUSG00000021958(Pinx1) "ENSG00000186566(GPATCH8),ENSG00000182348(ZNF804B),ENSG00000170396(ZNF804A)" "lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0010927 l(3)08126 lethal (3) 08126 http://flybase.net/reports/FBgn0010927.html FBgn0011325 gene l(3)j2B3 16-Dec-15 2015_12 "lethal,recessive" FBgn0069176 mcl(2)Z4579 mcl(2)Z4579 http://flybase.net/reports/FBgn0069176.html gene 0007140=male meiosis 16-Dec-15 2015_12 male fertile onion stage spermatid & nucleus FBgn0030121 Cfp1 CXXC finger protein 1 http://flybase.net/reports/FBgn0030121.html protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" 0051568=histone H3-K4 methylation 0048188=Set1C/COMPASS complex "CG17446, CXXC1, dCXXC1, dCfp1" "IPR019787=Zinc finger, PHD-finger, IPR022056=CpG binding protein, C-terminal, IPR002857=Zinc finger, CXXC-type, IPR011011=Zinc finger, FYVE/PHD-type, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type" CG17446 16-Dec-15 2015_12 "ENSDARG00000025718(cxxc1),ENSDARG00000016187(cxxc1l)" ENSXETG00000021938(cxxc1) ENSMUSG00000024560(Cxxc1) ENSG00000154832(CXXC1) "viable,partially lethal - majority die,some die during pupal stage" FBgn0011031 l(3)s2564 lethal (3) s2564 http://flybase.net/reports/FBgn0011031.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001463 l(1)7Ed lethal (1) 7Ed http://flybase.net/reports/FBgn0001463.html gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260991 Incenp Inner centromere protein http://flybase.net/reports/FBgn0260991.html "FBgn0033156, FBgn0062193, FBgn0002666" protein_coding_gene "0008017=microtubule binding, 0005515=protein binding" "0016572=histone phosphorylation, 0051257=meiotic spindle midzone assembly, 0008104=protein localization, 0007065=male meiosis sister chromatid cohesion, 0051310=metaphase plate congression, 0000281=mitotic cytokinesis, 0007052=mitotic spindle organization, 0008356=asymmetric cell division, 0022008=neurogenesis, 0090307=mitotic spindle assembly, 0010032=meiotic chromosome condensation, 0007056=spindle assembly involved in female meiosis" "1990023=mitotic spindle midzone, 0005694=chromosome, 0030496=midbody, 0051233=spindle midzone, 0032133=chromosome passenger complex, 1990385=meiotic spindle midzone, 0000775=chromosome, centromeric region, 0000776=kinetochore, 0000793=condensed chromosome" "INCENP, CG12165, Inner Centromere Protein, mat(2)earlyQA26, dIncenp, mat(2)ea-C, anon-WO0118547.171, maternal effect early arrest C, DmINCENP, inner centromere protein, incenp" CG12165 16-Dec-15 2015_12 ENSXETG00000006735(incenp) ENSMUSG00000024660(Incenp) FBgn0005431 l(1)10Ea lethal (1) 10Ea http://flybase.net/reports/FBgn0005431.html "FBgn0001506, FBgn0001864" gene 16-Dec-15 2015_12 "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0002705 meg megaoculus http://flybase.net/reports/FBgn0002705.html gene 16-Dec-15 2015_12 "viable,male sterile,recessive,female sterile,visible" "eye,wing,wing vein" FBgn0039704 neo neyo http://flybase.net/reports/FBgn0039704.html protein_coding_gene "0016476=regulation of embryonic cell shape, 0003383=apical constriction" 0016021=integral component of membrane "neyo, CG7802, neo" "IPR003609=PAN/Apple domain, IPR001507=Zona pellucida domain" CG7802 16-Dec-15 2015_12 "WBGene00009541(cutl-17),WBGene00018256(cutl-28)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0031639 mRpS2 mitochondrial ribosomal protein S2 http://flybase.net/reports/FBgn0031639.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "CG2937, MRP-S2" "IPR023591=Ribosomal protein S2, flavodoxin-like domain, IPR001865=Ribosomal protein S2, IPR005706=Ribosomal protein S2, bacteria/mitochondria/plastid" CG2937 16-Dec-15 2015_12 ENSDARG00000068635(zgc:158760) YHL004W(MRP4) WBGene00020718(T23B12.3) ENSXETG00000022329(mrps2) ENSMUSG00000035772(Mrps2) ENSG00000122140(MRPS2) "viable,fertile,visible" trichogen cell FBgn0033054 CG14591 http://flybase.net/reports/FBgn0033054.html protein_coding_gene IPR026508=Transmembrane protein 164 CG14591 16-Dec-15 2015_12 WBGene00007959(C35C5.10) ENSXETG00000012428(TMEM164) ENSMUSG00000047045(Tmem164) ENSG00000157600(TMEM164) viable FBgn0037440 CRAT Carnitine O-Acetyl-Transferase http://flybase.net/reports/FBgn0037440.html protein_coding_gene 0004092=carnitine O-acetyltransferase activity 0006635=fatty acid beta-oxidation "0005777=peroxisome, 0005654=nucleoplasm, 0005739=mitochondrion" "Carnitine O-acetyl-transferase, CG1041" IPR000542=Acyltransferase ChoActase/COT/CPT CG1041 16-Dec-15 2015_12 "ENSDARG00000040248(crata),ENSDARG00000016545(zgc:154046),ENSDARG00000010382(LOC100334862)" YML042W(CAT2) WBGene00007175(B0395.3) "ENSXETG00000018965(crat),ENSXETG00000005161()" ENSMUSG00000026853(Crat) ENSG00000095321(CRAT) "viable,fertile" FBgn0020407 asun asunder http://flybase.net/reports/FBgn0020407.html protein_coding_gene "0009950=dorsal/ventral axis specification, 0051663=oocyte nucleus localization involved in oocyte dorsal/ventral axis specification, 0051642=centrosome localization, 0046843=dorsal appendage formation, 0034472=snRNA 3'-end processing, 0007283=spermatogenesis, 0007346=regulation of mitotic cell cycle" "0005737=cytoplasm, 0032039=integrator complex, 0005634=nucleus" "CG6814, IntS13, Maternal transcript 89Bb, Mat89Bb, Asunder, Integrator 13, Asu, ASUN, asun, asunder" IPR019355=Cell cycle regulator Mat89Bb CG6814 16-Dec-15 2015_12 ENSDARG00000011764(zgc:55466) WBGene00019822(R02D3.4) ENSXETG00000016500(TGas007o21.1) ENSMUSG00000040250(4933424B01Rik) ENSG00000064102(C12orf11) " adult stage , adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage | stage S9-10 , embryonic stage | 0-4 hr , adult stage && oogenesis stage | stage >=S10 " " testis

, follicle cell

, ovary

, nurse cell

, oocyte

" "male sterile,meiotic cell cycle defective,viable" "centrosome, with bor+t4,spermatocyte,spermatid,egg,dorsal appendage,maternal effect,egg chamber,ovary,micropyle | maternal effect,oocyte nucleus,centrosome,spermatozoon,onion stage spermatid,primary spermatocyte,aster & primary spermatocyte in meiotic prophase I,spindle & spermatocyte,nucleus & elongation stage spermatid,microtubule basal body & elongation stage spermatid,investment cone,nucleus & unfertilized egg,nucleus | blastoderm stage" FBgn0031589 CG3714 http://flybase.net/reports/FBgn0031589.html protein_coding_gene "0004514=nicotinate-nucleotide diphosphorylase (carboxylating) activity, 0004516=nicotinate phosphoribosyltransferase activity" "0009435=NAD biosynthetic process, 0006979=response to oxidative stress, 0019358=nicotinate nucleotide salvage" 0005829=cytosol AAF51037 "IPR002638=Quinolinate phosphoribosyl transferase, C-terminal, IPR006405=Nicotinate phosphoribosyltransferase pncB-type, IPR007229=Nicotinate phosphoribosyltransferase family" CG3714 16-Dec-15 2015_12 ENSDARG00000027930(naprt1) YOR209C(NPT1) WBGene00021882(Y54G2A.17) ENSXETG00000004671(NAPRT1) ENSMUSG00000022574(Naprt1) ENSG00000147813(NAPRT1) "partially lethal - majority die,some die during pupal stage" FBgn0036118 Blos2 "Biogenesis of lysosome-related organelles complex 1, subunit 2" http://flybase.net/reports/FBgn0036118.html protein_coding_gene 0005515=protein binding 0031083=BLOC-1 complex "CG14145, blos2, NP_648427, BLOS2, DmBlos2, BLOC-1 subunit 2" "IPR019269=Biogenesis of lysosome-related organelles complex-1, subunit 2" CG14145 16-Dec-15 2015_12 ENSDARG00000046081(zgc:111974) WBGene00022251(Y73B6BL.30) ENSXETG00000023568(bloc1s2) "ENSMUSG00000025201(Gm13540),ENSMUSG00000057506(Bloc1s2)" ENSG00000196072(BLOC1S2) FBgn0040823 dpr6 defective proboscis extension response 6 http://flybase.net/reports/FBgn0040823.html FBgn0047210 protein_coding_gene 0007606=sensory perception of chemical stimulus "Dpr-6, Dpr6, CG14162, dpr6, BcDNA:LD13525, defective proboscis response 6" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain" CG14162 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" WBGene00006985(zig-8) "ENSXETG00000019353(CADM3),ENSXETG00000026489(igsf4d),ENSXETG00000015391(CADM1),ENSXETG00000015112(CADM4)" ENSMUSG00000048534(Amica1) "ENSG00000105767(CADM4),ENSG00000182985(CADM1),ENSG00000175161(CADM2),ENSG00000162706(CADM3)" viable DRSC09005 IEK -2.103560721 -3.468354635 -0.894535706 2.520202704 0.908188822 1.858861151 FBgn0038471 CG5220 http://flybase.net/reports/FBgn0038471.html protein_coding_gene "0008650=rRNA (uridine-2'-O-)-methyltransferase activity, 0008175=tRNA methyltransferase activity" "0001510=RNA methylation, 0008033=tRNA processing" Dm TRM7 "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR028590=tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7, IPR015507=Ribosomal RNA large subunit methyltransferase E, IPR002877=Ribosomal RNA methyltransferase FtsJ domain" CG5220 16-Dec-15 2015_12 ENSDARG00000057089(ftsj1) YBR061C(TRM7) WBGene00011281(R74.7) ENSXETG00000006939(FTSJ3) ENSMUSG00000031171(Ftsj1) ENSG00000068438(FTSJ1) viable FBgn0039182 CG5728 http://flybase.net/reports/FBgn0039182.html protein_coding_gene 0003729=mRNA binding "0000381=regulation of alternative mRNA splicing, via spliceosome, 0006364=rRNA processing" "0005634=nucleus, 0005730=nucleolus" "IPR011990=Tetratricopeptide-like helical domain, IPR012340=Nucleic acid-binding, OB-fold, IPR022967=RNA-binding domain, S1, IPR003107=HAT (Half-A-TPR) repeat, IPR003029=S1 domain, IPR008847=Suppressor of forked" CG5728 16-Dec-15 2015_12 ENSDARG00000052480(pdcd11) YMR229C(RRP5) WBGene00002850(let-716) ENSXETG00000009482(PDCD11) ENSMUSG00000025047(Pdcd11) ENSG00000148843(PDCD11) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0015756 RpL9 Ribosomal protein L9 http://flybase.net/reports/FBgn0015756.html "FBgn0025200, FBgn0045928, FBgn0045929, FBgn0045930" protein_coding_gene "0019843=rRNA binding, 0003735=structural constituent of ribosome" "0007052=mitotic spindle organization, 0006412=translation, 0051298=centrosome duplication, 0000022=mitotic spindle elongation" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "anon-WO0153538.25, Rp L9, anon-WO0153538.27, M(2)32D, CG6141, anon-WO0153538.26, rpL9, unnamed, L9, anon-EST:fe3A6, anon-fast-evolving-3A6, Rpl9" "IPR020040=Ribosomal protein L6, alpha-beta domain, IPR002359=Ribosomal protein L6, conserved site-2, IPR000702=Ribosomal protein L6" CG6141 16-Dec-15 2015_12 ENSDARG00000037350(rpl9) "YNL067W(RPL9B),YGL147C(RPL9A)" WBGene00004420(rpl-9) ENSXETG00000012856(RPL9) "ENSMUSG00000047215(Rpl9),ENSMUSG00000047965(Rpl9-ps7),ENSMUSG00000071292(Gm5451)" "ENSG00000163682(RPL9),ENSG00000185078" embryonic stage -- adult stage "Minute,lethal,recessive,visible,dominant,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "macrochaeta,eye" DRSC03418 IEK -2.951546704 -1.747894895 0.733815849 -2.856036494 1.471229505 3.532773375 FBgn0031995 CG8475 http://flybase.net/reports/FBgn0031995.html "FBtr0079638, FBpp0079254, FBtr0079639, FBpp0079255" protein_coding_gene "0003824=catalytic activity, 0005516=calmodulin binding, 0008607=phosphorylase kinase regulator activity" 0005977=glycogen metabolic process 0005964=phosphorylase kinase complex "IPR011613=Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family, IPR008734=Phosphorylase kinase alpha/beta subunit, IPR012341=Six-hairpin glycosidase, IPR008928=Six-hairpin glycosidase-like" CG8475 16-Dec-15 2015_12 WBGene00022058(Y67D8A.1) ENSXETG00000003918(PHKB) ENSMUSG00000036879(Phkb) ENSG00000102893(PHKB) viable FBgn0032713 CG17323 http://flybase.net/reports/FBgn0032713.html protein_coding_gene 0015020=glucuronosyltransferase activity "0002121=inter-male aggressive behavior, 0008152=metabolic process" CT35071 IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG17323 16-Dec-15 2015_12 "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" pupal stage salivary gland

"behavior defective,recessive,viable" FBgn0045842 yuri yuri gagarin http://flybase.net/reports/FBgn0045842.html "FBgn0027922, FBgn0028511, FBgn0028877, FBgn0032561, FBgn0051732" protein_coding_gene "0007291=sperm individualization, 0042332=gravitaxis, 0032053=ciliary basal body organization" "0005635=nuclear envelope, 0005737=cytoplasm, 0070865=investment cone, 0016529=sarcoplasmic reticulum" "BG:DS07851.11, Yuri, CG12635, BG:DS05639.1, Yuri Gagarin, CG11860, CG31732" CG31732 16-Dec-15 2015_12 "viable,fertile,auditory perception defective,gravitaxis defective,sterile,male limited" "spermatozoon,spermatid cyst,spermatid,investment cone,ciliary basal body,filamentous actin" FBgn0039213 atl atlastin http://flybase.net/reports/FBgn0039213.html protein_coding_gene "0032561=guanyl ribonucleotide binding, 0005525=GTP binding, 0003924=GTPase activity, 0042803=protein homodimerization activity" "0031114=regulation of microtubule depolymerization, 0061025=membrane fusion, 0007528=neuromuscular junction development, 0016320=endoplasmic reticulum membrane fusion, 0008582=regulation of synaptic growth at neuromuscular junction" "0005783=endoplasmic reticulum, 0005794=Golgi apparatus, 0005737=cytoplasm, 0012505=endomembrane system, 0031227=intrinsic component of endoplasmic reticulum membrane" "D-atlastin, CG6668, ATL, Atlastin" "IPR003191=Guanylate-binding protein, C-terminal, IPR030386=GB1/RHD3-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR015894=Guanylate-binding protein, N-terminal" CG6668 16-Dec-15 2015_12 "ENSDARG00000060481(atl1),ENSDARG00000057719(atl2),ENSDARG00000004270(atl3)" WBGene00021868(Y54G2A.2) "ENSXETG00000013737(ATL2),ENSXETG00000009126(ATL1),ENSXETG00000002686(TEgg024f16.1)" "ENSMUSG00000059811(Atl2),ENSMUSG00000021066(Atl1),ENSMUSG00000024759(Atl3)" "ENSG00000119787(ATL2),ENSG00000198513(ATL1),ENSG00000184743(ATL3)" "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,small body,recessive,sterile,viable,fertile,bang sensitive,short lived,locomotor behavior defective,lethal" "NMJ bouton,abdominal 2 ventral longitudinal muscle 3,abdominal 2 ventral longitudinal muscle 4,postsynaptic membraneExel7357),microtubule & embryonic/larval somatic muscleExel7357),imaginal disc,somatic clone,oocyte,dopaminergic neuron,endoplasmic reticulum,microtubule & embryonic/larval somatic muscleC57,embryonic/larval somatic muscle,endoplasmic reticulumë±Tub84B.PL,endoplasmic reticulumD42" FBgn0023441 fus fusilli http://flybase.net/reports/FBgn0023441.html "FBgn0015696, FBgn0034034" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding" "0043484=regulation of RNA splicing, 0007173=epidermal growth factor receptor signaling pathway" 0005634=nucleus "CG8205, Enhancer of cactus[E10], number 7, Fusilli, E(cact[E10])7, unnamed, cg8205" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR012337=Ribonuclease H-like domain, IPR000504=RNA recognition motif domain" CG8205 16-Dec-15 2015_12 "ENSDARG00000018814(esrp2),ENSDARG00000011245(esrp1)" WBGene00006367(sym-2) ENSXETG00000014667(BC076946.1) "ENSMUSG00000040728(Esrp1),ENSMUSG00000084128(Esrp2)" "ENSG00000104413(ESRP1),ENSG00000103067(ESRP2)" " adult stage && oogenesis stage , embryonic stage | stage 9 , embryonic stage | stage 13 , embryonic stage | stage 11 " " follicle cell

, proctodeum

, stomodeum

, embryonic/larval posterior spiracle

, ectoderm

segmentally repeated , embryonic/larval fat body

, nurse cell

, embryonic foregut

, mesoderm

segmentally repeated " "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,body color defective,partially lethal - majority die,some die during pupal stage" "wing,posterior compartment,mesothoracic tergum" FBgn0001782 l(1)M75 lethal (1) M75 http://flybase.net/reports/FBgn0001782.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0051297 CG31297 http://flybase.net/reports/FBgn0051297.html protein_coding_gene 16-Dec-15 2015_12 FBgn0039016 Dcr-1 Dicer-1 http://flybase.net/reports/FBgn0039016.html protein_coding_gene "0003727=single-stranded RNA binding, 0003725=double-stranded RNA binding, 0070883=pre-miRNA binding, 0005515=protein binding, 0016443=bidentate ribonuclease III activity" "0007279=pole cell formation, 0007367=segment polarity determination, 0030422=production of siRNA involved in RNA interference, 0042594=response to starvation, 0035196=production of miRNAs involved in gene silencing by miRNA, 0007294=germarium-derived oocyte fate determination, 0042078=germ-line stem cell division, 0031054=pre-miRNA processing, 0033227=dsRNA transport, 0035087=siRNA loading onto RISC involved in RNA interference, 0030727=germarium-derived female germ-line cyst formation, 0016246=RNA interference, 0048813=dendrite morphogenesis, 0045448=mitotic cell cycle, embryonic" "0005634=nucleus, 0005737=cytoplasm, 0016442=RISC complex" "DICER-1, dicer-1, DCR-1, Dicer, CG4792, dcr 1, Dcr, Dicer 1, dicer1, dcr-1, dcr1, dicer, Dcr1, DICER, Dicer1, Dicer-1, cg4792, DCR1" "IPR003100=PAZ domain, IPR001650=Helicase, C-terminal, IPR014720=Double-stranded RNA-binding domain, IPR000999=Ribonuclease III domain, IPR005034=Dicer dimerisation domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG4792 16-Dec-15 2015_12 ENSDARG00000001129(dicer1) WBGene00000939(dcr-1) ENSMUSG00000041415(Dicer1) ENSG00000100697(DICER1) "lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,somatic clone,neuroanatomy defective,decreased cell growth,visible,lethal,recessive,lethal - all die during embryonic stage,decreased cell number,mitotic cell cycle defective,increased cell death,hypoplasia,somatic clone - Minute background,lethal - all die before end of embryonic stage,some die during embryonic stage,suppressor of variegation,size defective,partially lethal - majority die,viable" "oocyte,germline clone,ovariole,germline stem cell,dendrite | somatic clone,abdominal 1 dorsal multidendritic neuron ddaC,somatic clone,wing disc,eye,dendrite & ad PN | somatic clone,dendrite & lPN | somatic clone,dendrite & vPN | somatic clone,dendrite & DL1 adPN | somatic clone,dendrite & DA1 lPN | somatic clone,axon & DL1 adPN | somatic clone,antennal lobe projection neuron adPN,adult antennal lobe projection neuron DL1 adPN,antennal lobe projection neuron lPN,mushroom body,alpha/beta Kenyon cell,alpha'/beta' Kenyon cell,pole cell,maternal effect,wing,chaeta & mesothoracic tergum | somatic clone,eye disc,female germline stem cell,wing margin bristle,somatic clone - Minute background,wing blade,wing disc | third instar larval stage,embryonic/larval neuromuscular junction" FBgn0033159 Dscam1 Down syndrome cell adhesion molecule 1 http://flybase.net/reports/FBgn0033159.html "FBgn0004124, FBgn0010604" protein_coding_gene "0003823=antigen binding, 0042802=identical protein binding, 0042803=protein homodimerization activity, 0008046=axon guidance receptor activity" "0050770=regulation of axonogenesis, 0016319=mushroom body development, 0070593=dendrite self-avoidance, 0006909=phagocytosis, 0007419=ventral cord development, 0032490=detection of molecule of bacterial origin, 0048846=axon extension involved in axon guidance, 0048666=neuron development, 0007422=peripheral nervous system development, 0021551=central nervous system morphogenesis, 0007411=axon guidance, 0050976=detection of mechanical stimulus involved in sensory perception of touch, 0007413=axonal fasciculation, 0048814=regulation of dendrite morphogenesis" "0043025=neuronal cell body, 0030424=axon, 0030425=dendrite, 0005887=integral component of plasma membrane, 0043005=neuron projection" "p270, dscam, DsCam, Down's syndrome cell adhesion molecule, Dsm, DScam, CT39257, Dscam-hv, Down's syndrome Cell Adhesion Molecule, FBgn0033159, l(2)05518, Dscam1, DmDscam, Down syndrome cell-adhesion molecule, Dm_2R:13579, Down Syndrome Cell Adhesion Molecule, Drosophila Down syndrome cell adhesion molecule, l(2)43Bc, CG17800, DSCAM, Neu1, 43Bc, dScam, Dscam, Dm_2R:13612, Down Syndrome cell adhesion molecule, Drosophila Down syndrome cell adhesion molecule 1, Down syndrome cell adhesion molecule, lethal(2)43Bc" "IPR003598=Immunoglobulin subtype 2, IPR021012=Down syndrome cell adhesion molecule, C-terminal, IPR013151=Immunoglobulin, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype" CG17800 16-Dec-15 2015_12 "ENSDARG00000024865(dscam),ENSDARG00000028118(LOC565371),ENSDARG00000057052(LOC100002762)" ENSXETG00000003741(DSCAML1) "ENSMUSG00000050272(Dscam),ENSMUSG00000032087(Dscaml1)" "ENSG00000171587(DSCAM),ENSG00000177103(DSCAML1)" embryonic stage | stage 5 ventral neurogenic region | restricted

"neuroanatomy defective,somatic clone,viable,lethal,recessive,wild-type,fertile,dominant,lethal - all die before end of larval stage,some die during larval stage,touch sensitivity defective,touch perception defective,cell non-autonomous" "dendritic arborizing neuron,mushroom body alpha-lobe,mushroom body beta-lobe,adult antennal lobe projection neuron vPN,lateral horn,adult antennal lobe,embryonic/larval mushroom body,mushroom body pedunculus,antennal lobe,somatic clone,posterior dorsocentral bristle & mechanosensory neuron | somatic clone,anterior scutellar bristle & mechanosensory neuron | somatic clone,posterior scutellar bristle & mechanosensory neuron | somatic clone,lobe system of mushroom body,dorsal multidendritic neuron ddaC,class I dendritic arborizing neuron,posterior scutellar bristle & mechanosensory neuron,dendrite & abdominal dorsal multidendritic neuron ddaD,dendrite & abdominal dorsal multidendritic neuron ddaE,longitudinal connective,presumptive embryonic/larval central nervous system,antennal lobe glomerulus,olfactory receptor neuron,adult antennal lobe projection neuron DL1 adPN,dendritic tree | somatic clone,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1v,neuroblast BLV,adult mushroom body,mushroom body,mushroom body pedunculus | third instar larval stage,antennal lobe glomerulus VA1d | pupal stage,antennal lobe glomerulus DA1 | pupal stage,antennal lobe glomerulus VA1d,ectopic,axon,commissure,Bolwig nerve,synapse,synapseppk.PG,neuron & mushroom body | somatic clone,lobe system of adult mushroom body,embryonic/larval hemocyte,mushroom body medial lobe,mushroom body vertical lobe,mechanosensory neuron,axon | ectopic,mushroom body dorsal paired medial cell,calyx of adult mushroom body,cell non-autonomous,ellipsoid body,mushroom body calyx,antennal lobe glomerulus DL1,dendrite & abdominal dorsal multidendritic neuron ddaD | somatic clone | cell autonomous,dendrite & abdominal dorsal/lateral multidendritic neuron | somatic clone | cell autonomous,dendrite & abdominal dorsal multidendritic neuron ddaA | somatic clone | cell autonomous,dendrite & abdominal dorsal multidendritic neuron ddaC | somatic clone | cell autonomous,dendrite & dendritic arborising neuron | somatic clone | cell autonomous,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,posterior commissure" FBgn0015376 cutlet cutlet http://flybase.net/reports/FBgn0015376.html "FBgn0031565, FBgn0053122" protein_coding_gene "0003677=DNA binding, 0005524=ATP binding" "0008283=cell proliferation, 0006260=DNA replication" 0005634=nucleus "CG33122, Cutlet, ctl, gilead, CG10030" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR003593=AAA+ ATPase domain" CG33122 16-Dec-15 2015_12 ENSDARG00000058480(chtf18) YMR078C(CTF18) WBGene00010676(K08F4.1) ENSXETG00000005776(CHTF18) ENSMUSG00000019214(Chtf18) ENSG00000127586(CHTF18) "visible,recessive,viable,female sterile,lethal,wild-type,male sterile,partially,increased cell death,partially lethal - majority die" "ommatidium,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,wing disc,somatic clone,eye disc,ventral thoracic disc,wing,egg chamber,germline cell,female,wing margin,posterior,interommatidial bristle,ocellar bristle,cone cell,eye disc & mitotic cell cycle,photoreceptor cell,supernumerary" FBgn0026411 Lim1 http://flybase.net/reports/FBgn0026411.html "FBgn0028495, FBgn0030064" protein_coding_gene "0008270=zinc ion binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007480=imaginal disc-derived leg morphogenesis, 0045892=negative regulation of transcription, DNA-templated, 0010468=regulation of gene expression, 0007479=leg disc proximal/distal pattern formation, 0006355=regulation of transcription, DNA-templated, 0045893=positive regulation of transcription, DNA-templated, 0048749=compound eye development" 0005634=nucleus "CG10760, Lim1, lim1, Lim, dlim-1, dlim1, Dlim1, dLim1, BcDNA:GH04929, Lim kinase, CG11354" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain, IPR001781=Zinc finger, LIM-type" CG11354 16-Dec-15 2015_12 "ENSDARG00000014018(lhx1a),ENSDARG00000007944(lhx1b),ENSDARG00000057936(lhx5)" WBGene00003000(lin-11) "ENSXETG00000008963(LHX1),ENSXETG00000017665(lhx5)" "ENSMUSG00000018698(Lhx1),ENSMUSG00000029595(Lhx5)" "ENSG00000132130(LHX1),ENSG00000089116(LHX5)" "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,visible,wild-type,locomotor behavior defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,viable" "unguis,femur,tibia,antenna,arista,coxa,sternopleural bristle,vibrissae,mouthpart,third segment of antenna,larva,adult antennal lobe projection neuron DA1 vPN,eye,eye disc,somatic clone | third instar larval stage,photoreceptor cell,tarsal segment 4,tarsal segment,tarsal segment 2,tarsal segment 3,metatarsus" FBgn0027579 mino minotaur http://flybase.net/reports/FBgn0027579.html protein_coding_gene 0004366=glycerol-3-phosphate O-acyltransferase activity "0034587=piRNA metabolic process, 0008654=phospholipid biosynthetic process, 0007009=plasma membrane organization" "0005886=plasma membrane, 0005741=mitochondrial outer membrane, 0005783=endoplasmic reticulum, 0045169=fusome, 0005739=mitochondrion, 0035324=female germline ring canal" "152088_at, CG5508, BcDNA:GH07066, GPAT1" "IPR028354=Glycerol-3-phosphate acyltransferase, PlsB, IPR022284=Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase, IPR002123=Phospholipid/glycerol acyltransferase" CG5508 16-Dec-15 2015_12 WBGene00017261(acl-6) ENSMUSG00000024978(Gpam) ENSG00000119927(GPAM) "viable,male sterile,recessive,female sterile,female fertile" "salivary gland,lipid particle | ectopicppl.PP,lipid particle | ectopic48Y" FBgn0002735 E(spl)më_-HLH "Enhancer of split më_, helix-loop-helix" http://flybase.net/reports/FBgn0002735.html protein_coding_gene "0008134=transcription factor binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0046983=protein dimerization activity" "0048190=wing disc dorsal/ventral pattern formation, 0007219=Notch signaling pathway, 0048749=compound eye development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007399=nervous system development, 0045892=negative regulation of transcription, DNA-templated, 0002052=positive regulation of neuroblast proliferation" 0005634=nucleus "anon-EST:Liang-1.49, HlHmg, mB, split locus enhancer protein mB, E(spl) region transcript g, gamma, mg, mgamma, E(spl) mgamma, HLHMgamma, E(spl)gamma, E(spl)-mgamma, CG8333, clone 1.49, Enhancer of split region transcript HLHmB, E(spl) region transcript mgamma, E(Spl) HLH-m gamma, Mgamma, E(spl) m gamma, Enhancer of split mgamma, Dm-mB, e(spl)mgamma, E(spl)Mgamma, E(spl)mgamma, HLH-mgamma, E(spl)mB, bHLHb34, HLHmB, HLHmgamma, E(spl) mg" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG8333 16-Dec-15 2015_12 ENSDARG00000014722(her1) "increased cell number,viable,visible,neuroanatomy defective" "embryonic/larval neuroblast,macrochaeta,microchaeta,adult thorax,dorsal row & sensory mother cellap-md544,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutellar bristle,wing vein,wing margin bristle,scutum & microchaeta32B,scutum & macrochaetah-1J3,chordotonal organ precursor cell & ventral thoracic disc-109-68,type II neuroblast" FBgn0030343 ATP7 ATP7 http://flybase.net/reports/FBgn0030343.html protein_coding_gene "0004008=copper-exporting ATPase activity, 0005375=copper ion transmembrane transporter activity, 0000166=nucleotide binding, 0005507=copper ion binding" "0048066=developmental pigmentation, 0002164=larval development, 0048085=adult chitin-containing cuticle pigmentation, 0006825=copper ion transport, 0055065=metal ion homeostasis, 0006878=cellular copper ion homeostasis" "0005737=cytoplasm, 0005886=plasma membrane, 0016021=integral component of membrane" "CG1886, dmATP7, lincRNA.S9122, DmATP7" "IPR023299=P-type ATPase, cytoplasmic domain N, IPR017969=Heavy-metal-associated, conserved site, IPR006122=Heavy metal-associated domain, copper ion-binding, IPR023214=HAD-like domain, IPR027256=P-type ATPase, subfamily IB, IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR006121=Heavy metal-associated domain, HMA, IPR001757=P-type ATPase" CG1886 16-Dec-15 2015_12 "ENSDARG00000003699(atp7a),ENSDARG00000058145(LOC556499)" YBR295W(PCA1) WBGene00000834(cua-1) ENSXETG00000020713() "ENSMUSG00000033792(Atp7a),ENSMUSG00000006567(Atp7b)" "ENSG00000165240(ATP7A),ENSG00000215763,ENSG00000123191(ATP7B)" "size defective,neuroanatomy defective,oxidative stress response defective,partially lethal - majority die,some die during pharate adult stage,locomotor behavior defective,viable,nutrition conditional,short lived,visible,lethal - all die before end of pupal stage,some die during pupal stage,male sterile,body color defective,lethal,germline clone,maternal effect,lethal - all die before end of larval stage,some die during larval stage,chemical sensitive" "pupal brain,eye,nutrition conditional,adult cuticle,macrochaeta,microchaeta,trichogen cell,mesothoracic tergum,mouth hooks,tergite,trident,macrochaeta & mesothoracic tergumpnr-MD237,scutellum,adult thorax,adult thoracic sensillum,scutellar bristle" FBgn0034113 CG8060 http://flybase.net/reports/FBgn0034113.html protein_coding_gene "IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR000210=BTB/POZ domain, IPR011333=POZ domain, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain, IPR000408=Regulator of chromosome condensation, RCC1" CG8060 16-Dec-15 2015_12 "ENSDARG00000036645(rcbtb1),ENSDARG00000068502" ENSXETG00000018679(IBTK) ENSMUSG00000035941(Ibtk) ENSG00000005700(IBTK) "viable,fertile" FBgn0001197 His2Av Histone H2A variant http://flybase.net/reports/FBgn0001197.html FBgn0010859 protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0035019=somatic stem cell maintenance, 0006333=chromatin assembly or disassembly, 0071168=protein localization to chromatin, 0006974=cellular response to DNA damage stimulus, 0036098=male germ-line stem cell maintenance" "0005634=nucleus, 0005694=chromosome, 0000786=nucleosome, 0005701=polytene chromosome chromocenter, 0005811=lipid particle, 0005700=polytene chromosome" "5499, His2, Histone2Av, histone H2A variant, H2av, H2A.Z, H2A.F/Z, H2AV, HIS, h2AvD, l(3)97Dd, His2A, HisH2Av, l(3)L1602, histone2AvD, his, his2Av, Hist, H2AvD, histone, H2avD, His, H2AZ, gamma-H2Av, CG5499, histone variant H2Av, histone2Av, H2Av, histone2A, HIS2AVD, histone 2A variant, His2AV, Histone-2av, H2AV_DROM, H2A.X, gamma-HIS2AV, Hist2av, H2AX, Histone, His2AvD, gammaH2Av, H2A.V, l(3)810, H2A, H2A variant, l(3)05146, Histone-2A, gamma-His2Av, H2a.V, HIS2AV, histone H2Av" "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A" CG5499 16-Dec-15 2015_12 "ENSDARG00000068820(h2afv),ENSDARG00000068016(h2afz),ENSDARG00000042502(h2afvl)" YOL012C(HTZ1) WBGene00019947(htz-1) ENSXETG00000001258(h2afv) "ENSMUSG00000037894(H2afz),ENSMUSG00000041126(H2afv)" "ENSG00000105968(H2AFV),ENSG00000164032(H2AFZ)" " adult stage | female , embryonic stage | 0-12 hr " "lethal,recessive,partially lethal - majority die,female semi-sterile,visible,wild-type,suppressor of variegation,dominant,radiation sensitive,lethal - all die before end of larval stage,some die during larval stage,enhancer of variegation,viable,some die during pupal stage,female sterile" "polytene chromosome puff | heat sensitive,eye,tarsal segment,anterior crossvein,mesothoracic tergum" DRSC16702 E -0.380515338 0.540796694 0.010369878 -2.058181484 1.179307842 0.284934271 FBgn0037166 CG11426 http://flybase.net/reports/FBgn0037166.html protein_coding_gene 0008195=phosphatidate phosphatase activity "0006644=phospholipid metabolic process, 0007602=phototransduction, 0016311=dephosphorylation" 0016020=membrane "WUN-like, lipid phosphate phosphohydrolase, Css1beta, PAP2, LPP-like, LPP" IPR000326=Phosphatidic acid phosphatase type 2/haloperoxidase CG11426 16-Dec-15 2015_12 "ENSDARG00000059933(si:dkey-19f4.1),ENSDARG00000069940(zgc:158309),ENSDARG00000002231(LOC563806),ENSDARG00000028896(zgc:66434)" WBGene00018756(F53C3.13) "ENSXETG00000011144(ppap2b),ENSXETG00000000375(ppap2a),ENSXETG00000026886(ppap2c)" "ENSMUSG00000028517(Ppap2b),ENSMUSG00000021759(Ppap2a),ENSMUSG00000052151(Ppap2c)" "ENSG00000067113(PPAP2A),ENSG00000141934(PPAP2C),ENSG00000162407(PPAP2B)" viable "wing hair,supernumerary" DRSC11658 IK 1.902934753 0.470071708 0.005548038 0.57973259 1.519417659 1.406683511 FBgn0014029 2-Sep Septin 2 http://flybase.net/reports/FBgn0014029.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity, 0042803=protein homodimerization activity, 0005515=protein binding" "0007349=cellularization, 0000281=mitotic cytokinesis, 0007295=growth of a germarium-derived egg chamber, 0051726=regulation of cell cycle, 0022008=neurogenesis, 0007444=imaginal disc development" "0031105=septin complex, 0005940=septin ring, 0045172=germline ring canal, 0005875=microtubule associated complex" "38961, unnamed, sep2, septin-2, septin2, Septin-2, Septin2, CG4173, septin, septin 2" "IPR016491=Septin, IPR030379=Septin-type guanine nucleotide-binding (G) domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG4173 16-Dec-15 2015_12 "ENSDARG00000010721(sept6),ENSDARG00000011164(sept10),ENSDARG00000032606(sept8a),ENSDARG00000014233(sept8b)" WBGene00006795(unc-61) "ENSXETG00000007443(SEPT6),ENSXETG00000006404(sept8),ENSXETG00000013836(sept10)" "ENSMUSG00000058013(Sept11),ENSMUSG00000050379(Sept6),ENSMUSG00000018398(Sept8),ENSMUSG00000019917(Sept10)" "ENSG00000138758(SEPT11),ENSG00000125354(SEPT6),ENSG00000164402(SEPT8),ENSG00000186522(SEPT10)" "viable,fertile,partially lethal,maternal effect,paternal effect,male semi-sterile,female semi-sterile,cell cycle defective,some die during pharate adult stage,lethal,neuroanatomy defective,visible" "egg,maternal effect,nurse cell,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0037715 CG9399 http://flybase.net/reports/FBgn0037715.html protein_coding_gene 0050833=pyruvate transmembrane transporter activity 0006850=mitochondrial pyruvate transport "0016021=integral component of membrane, 0031305=integral component of mitochondrial inner membrane" IPR005336=Mitochondrial pyruvate carrier CG9399 16-Dec-15 2015_12 "ENSDARG00000024478(brp44),ENSDARG00000037679(zgc:103678)" "YHR162W(),YGR243W(FMP43)" WBGene00018765(F53F10.3) ENSXETG00000025716(brp44) ENSMUSG00000026568(Brp44) ENSG00000143158(BRP44) viable DRSC16488 I 1.632597993 -0.057277898 -0.233368358 0.332414739 -0.80851097 -0.020273961 FBgn0043576 PGRP-SC1a PGRP-SC1a http://flybase.net/reports/FBgn0043576.html FBgn0033325 protein_coding_gene "0008745=N-acetylmuramoyl-L-alanine amidase activity, 0042834=peptidoglycan binding, 0008270=zinc ion binding" "0006955=immune response, 0006952=defense response, 0009253=peptidoglycan catabolic process, 0045824=negative regulation of innate immune response" "0005887=integral component of plasma membrane, 0005576=extracellular region" "picky, PGRP SC, Peptidoglycan-recognition protein-SC1a precursor, PGRP-SC1, PGRP-SC1A, PGRP-SC, CG14746" "IPR017331=Peptidoglycan recognition protein, PGRP-S, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510=Peptidoglycan recognition protein, IPR002502=N-acetylmuramoyl-L-alanine amidase domain" CG14746 16-Dec-15 2015_12 "ENSDARG00000023215,ENSDARG00000068382(pglyrp5)" "ENSXETG00000018262(BC089715.1),ENSXETG00000019028(BC091103.1)" ENSMUSG00000030413(Pglyrp1) ENSG00000008438(PGLYRP1) "viable,immune response defective" FBgn0041210 HDAC4 Histone deacetylase 4 http://flybase.net/reports/FBgn0041210.html "FBgn0030464, FBgn0063926" protein_coding_gene 0004407=histone deacetylase activity "0006355=regulation of transcription, DNA-templated, 0016573=histone acetylation, 0016575=histone deacetylation, 0007616=long-term memory, 0007613=memory" "0005737=cytoplasm, 0005634=nucleus" "HDAC4a, CG1770, Histone Deacetylase 4, hdac4, dHDAC4, dmHDA405, HDAC, HDAC4, DHDAC4, GC1770" "IPR000286=Histone deacetylase superfamily, IPR023801=Histone deacetylase domain" CG1770 16-Dec-15 2015_12 ENSDARG00000041204(hdac4) WBGene00001837(hda-4) "ENSXETG00000004880(HDAC4),ENSXETG00000010661(HDAC7)" "ENSMUSG00000004698(Hdac9),ENSMUSG00000008855(Hdac5),ENSMUSG00000026313(Hdac4)" "ENSG00000048052(HDAC9),ENSG00000108840(HDAC5),ENSG00000068024(HDAC4)" "viable,memory defective,fertile,body color defective" mesothoracic tergum FBgn0040298 Myt1 Myt1 http://flybase.net/reports/FBgn0040298.html "FBgn0035634, FBgn0052417" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0004712=protein serine/threonine/tyrosine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0048142=germarium-derived cystoblast division, 0007284=spermatogonial cell division, 0048133=male germ-line stem cell asymmetric division, 0007095=mitotic G2 DNA damage checkpoint, 0007140=male meiosis, 0045930=negative regulation of mitotic cell cycle, 0048137=spermatocyte division, 0045793=positive regulation of cell size, 0000086=G2/M transition of mitotic cell cycle, 0007143=female meiotic division, 0007126=meiotic nuclear division" "0005794=Golgi apparatus, 0016020=membrane, 0005737=cytoplasm" "dMyt1, Dmyt1, myt1, CG10569, CG32417, MYT 1, MYT1" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR016235=Tyrosine/threonine-protein kinase, Cdc2 inhibitor, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain" CG32417 16-Dec-15 2015_12 ENSG00000127564(PKMYT1) "visible,mitotic cell cycle defective,male sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable" "ommatidium,eye disc,ommatidial precursor cluster,rhabdomere,secondary pigment cell,tertiary pigment cell,eye photoreceptor cell,supernumerary,macrochaeta & adult head64D-F),macrochaeta & adult thorax64D-F),macrochaeta & eye64D-F),cyst cell & nucleus64D-F),meiotic cell cycle64D-F),mitotic cell cycle & cystocyte64D-F),mitotic cell cycle & cystoblast64D-F),primary spermatocyte" DRSC11228 IE 1.93951296 0.05098842 0.28188664 -3.229741878 1.069769075 -0.792810332 FBgn0020379 Rfx Rfx http://flybase.net/reports/FBgn0020379.html protein_coding_gene 0043565=sequence-specific DNA binding "0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0007605=sensory perception of sound" 0005634=nucleus "regulatory factor X, rfx, CG6312, Regulatory factor X, dRfx, dRFX, RFX" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR003150=DNA-binding RFX-type winged-helix domain" CG6312 16-Dec-15 2015_12 "ENSDARG00000014550,ENSDARG00000013575(rfx2),ENSDARG00000005883(rfx1a)" "ENSXETG00000005567(RFX1),ENSXETG00000021877(RFX2)" "ENSMUSG00000024206(Rfx2),ENSMUSG00000040929(Rfx3),ENSMUSG00000031706(Rfx1)" "ENSG00000080298(RFX3),ENSG00000087903(RFX2),ENSG00000132005(RFX1)" "viable,fertile,smell perception defective,taste perception defective,uncoordinated,neurophysiology defective,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" "macrochaeta,antenna,Johnston's organ & scolopidium,Johnston's organ & scolopidial cilium,Johnston's organ & scolopale,sensillum campaniformium & wing sensillum & dendrite,sensillum campaniformium & wing sensillum,abdominal lateral pentascolopidial chordotonal organ lch5,abdominal lateral pentascolopidial chordotonal organ lch5 & dendrite,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial cilium,chordotonal organ & leg sensillumS143702),chordotonal organ & leg sensillum & scolopidial ciliumS143702)" FBgn0025808 Rad17 Rad17 http://flybase.net/reports/FBgn0025808.html protein_coding_gene "0007049=cell cycle, 0006281=DNA repair" 0005634=nucleus "CG7825, DmRad17/24" "IPR004582=Checkpoint protein Rad17/Rad24, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG7825 16-Dec-15 2015_12 ENSDARG00000018918(rad17) YER173W(RAD24) ENSXETG00000018168(RAD17) ENSMUSG00000021635(Rad17) ENSG00000152942(RAD17) viable FBgn0010398 Lrr47 Leucine-rich repeat 47 http://flybase.net/reports/FBgn0010398.html protein_coding_gene "0046331=lateral inhibition, 0022008=neurogenesis, 0007265=Ras protein signal transduction" "0005576=extracellular region, 0005737=cytoplasm, 0019898=extrinsic component of membrane, 0005634=nucleus" "CG6098, Lrr-47, CT19173, LRR47" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG6098 16-Dec-15 2015_12 ENSXETG00000009119(ppil5) ENSMUSG00000034883(Ppil5) ENSG00000165501(LRR1) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum" FBgn0032447 PICK1 Protein interacting with C kinase 1 http://flybase.net/reports/FBgn0032447.html protein_coding_gene "0019904=protein domain specific binding, 0005543=phospholipid binding" "0048639=positive regulation of developmental growth, 0045055=regulated secretory pathway, 0071329=cellular response to sucrose stimulus" 0043025=neuronal cell body "CG6167, protein interacting with C kinase 1, PICK1 ortholog, PICK1, Protein interacting with C kinase 1" "IPR010504=Arfaptin homology (AH) domain, IPR001478=PDZ domain, IPR027267=Arfaptin homology (AH) domain/BAR domain, IPR030798=Arfaptin family" CG6167 16-Dec-15 2015_12 ENSDARG00000071152(zgc:153257) WBGene00013317(Y57G11C.22) ENSXETG00000010815(TNeu062j22.2) ENSMUSG00000068206(Pick1) ENSG00000100151(PICK1) "viable,fertile,visible" trichogen cell FBgn0053855 His1:CG33855 His1:CG33855 http://flybase.net/reports/FBgn0053855.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33855 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5" CG33855 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0003507 srp serpent http://flybase.net/reports/FBgn0003507.html "FBgn0010376, FBgn0010753, FBgn0011478" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0005515=protein binding, 0008270=zinc ion binding, 0044212=transcription regulatory region DNA binding" "0007435=salivary gland morphogenesis, 0007492=endoderm development, 0001709=cell fate determination, 0035050=embryonic heart tube development, 0042690=negative regulation of crystal cell differentiation, 0007503=fat body development, 0006909=phagocytosis, 0001710=mesodermal cell fate commitment, 0045893=positive regulation of transcription, DNA-templated, 0007516=hemocyte development, 0006952=defense response, 0048542=lymph gland development, 0046665=amnioserosa maintenance, 0042688=crystal cell differentiation, 0007390=germ-band shortening, 0006914=autophagy, 0030097=hemopoiesis, 0001700=embryonic development via the syncytial blastoderm, 0006355=regulation of transcription, DNA-templated, 0007494=midgut development, 0035162=embryonic hemopoiesis, 0008258=head involution, 0007391=dorsal closure, 0045165=cell fate commitment, 0001706=endoderm formation, 0008354=germ cell migration, 0035167=larval lymph gland hemopoiesis" 0005634=nucleus "SERPENT, DmGATAb, Srp, A7.1, A-box-binding factor, dGATAb, ABF, l(3)01549, serpentD, spt, Serpent, GATA, abf, SRP, GATAb, srpD, l(3)neo45, Abf, l(3)89B2, CG3992" "IPR013088=Zinc finger, NHR/GATA-type, IPR000679=Zinc finger, GATA-type, IPR014721=Ribosomal protein S5 domain 2-type fold, subgroup" CG3992 16-Dec-15 2015_12 " embryonic stage | stage 5 , embryonic stage | stage 11 , embryonic stage&&larval stage&&adult stage , embryonic stage | stage 5-9 , embryonic stage | stage 5-12 , embryonic stage | stage 6 , embryonic stage | >stage 12 " " vitellophage

, prohemocyte

, anterior midgut proper primordium

, posterior midgut proper primordium

, head mesoderm

, amnioserosa

, fat body

, prohemocyte | primordium

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,small body,cell migration defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/first instar larval cuticle,crystal cell,embryonic/larval lymph gland,embryonic/larval hemocyte,embryonic/larval tracheocyte,precursor,ventral midline,extended germ band embryo,macrochaeta,dorsal,amnioserosa,presumptive embryonic/larval central nervous system,embryonic/larval glial cell,embryonic hemocyte,plasmatocyte,abdomen,posterior,midgut primordium,embryonic/larval fat body,embryonic/larval midgut,germline cell,embryonic Malpighian tubule,presumptive embryonic salivary gland,visceral mesoderm,lymph gland primordium,dorsal closure embryo,midgut,embryo,embryonic head,cephalopharyngeal skeleton,dorsal bridge,vertical bridge,cuticle,ectopic,crystal cell | embryonic stage,plasmatocyte | embryonic stage,cardioblast,embryonic/larval garland cell,fat body/gonad primordium,gonadal sheath,embryonic/larval somatic muscle,midgut constriction,cardiogenic mesoderm,embryonic pericardial cell,posterior signalling centre of lymph gland primary lobe" DRSC23166 K 1.931612853 0.846987766 FBgn0000629 E(z) Enhancer of zeste http://flybase.net/reports/FBgn0000629.html FBgn0004710 protein_coding_gene "0046974=histone methyltransferase activity (H3-K9 specific), 0042054=histone methyltransferase activity, 0005515=protein binding, 0046976=histone methyltransferase activity (H3-K27 specific)" "0035186=syncytial blastoderm mitotic cell cycle, 0006723=cuticle hydrocarbon biosynthetic process, 0007517=muscle organ development, 0051567=histone H3-K9 methylation, 0070734=histone H3-K27 methylation, 0048813=dendrite morphogenesis, 0016571=histone methylation, 0042810=pheromone metabolic process, 0007411=axon guidance, 0006342=chromatin silencing, 0022008=neurogenesis" "0035098=ESC/E(Z) complex, 0005634=nucleus, 0035097=histone methyltransferase complex" "enhancer of zeste, EZH1/2, Enhancer-of-zeste, l(3)B12, l(3)SG17, l(3)1902, pco/E(z), Su(z)301, pco, E(z)1, Enhancer of Zeste, E[z], E(Z), l(3)ds12, enhancer of zest, polycombeotic, Ez, enhancer-of-zeste, CG6502, EZ, l(3)67Fa, Enhancer-of-Zeste" "IPR001214=SET domain, IPR001005=SANT/Myb domain, IPR026489=CXC domain" CG6502 16-Dec-15 2015_12 "ENSDARG00000010571(ezh2),ENSDARG00000037894" WBGene00003220(mes-2) ENSXETG00000020191(EZH1) "ENSMUSG00000029687(Ezh2),ENSMUSG00000006920(Ezh1)" "ENSG00000106462(EZH2),ENSG00000108799(EZH1)" " embryonic stage -- adult stage , adult stage | male , larval stage && pupal stage " " larval stage | third instar , embryonic stage "

ubiquitous "female sterile,endomitotic cell cycle defective,viable,lethal,recessive,visible,dominant,homeotic,eye color defective,wild-type,neuroanatomy defective,somatic clone,decreased cell number,mitotic cell cycle defective,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,poor,lethal - all die before end of larval stage,some die during larval stage,maternal effect,non-suppressor of variegation,non-enhancer of variegation,suppressor of variegation,partially lethal - majority die,some die during pupal stage" "egg chamber,oocyte nucleus,karyosome,germarium region 2b,adult metathoracic segment,adult mesothoracic segment,ectopic,adult abdominal segment 5,adult abdominal segment 4,adult prothoracic segment,mesothoracic leg & sex comb | ectopic,sex comb,pigment cell,mesothoracic leg,axon | somatic clone,CNS glial cell,somatic clone,neuroblast,wing,segment,heat sensitive,polytene chromosome | heat sensitive,wing disc,haltere disc,adult abdominal segment 6,adult abdominal segment 7,haltere,humerus,female genitalia,ventral,male genitalia,leg,posterior compartment,triple row,tergite,metathoracic leg,egg,nurse cell,imaginal disc,maternal effect,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval abdominal segment 7,larval abdominal segment 8,larval abdominal segment 9,larval abdominal segment 10,larval abdominal segment 11,larval thorax,photoreceptor cell,eye,eye disc,morphogenetic furrow,metaphase & condensed chromosome & embryo,dendrite & dorsal multidendritic neuron ddaC | somatic clone,larval brain & mitosis & nuclear chromosome,cell cycle,eye-antennal disc,ventral thoracic disc,genital disc,mesothoracic tergum" FBgn0004969 ado adolescent http://flybase.net/reports/FBgn0004969.html gene 0048477=oogenesis l(1)4P1 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "chorion | germline clone,dorsal appendage,germline clone,ovary,ovariole,somatic clone,egg" FBgn0262389 mir-1017 mir-1017 stem loop http://flybase.net/reports/FBgn0262389.html "FBgn0250813, FBgn0262212" miRNA_gene "CR42919, miR-1017, dme-mir-1017" CR42919 16-Dec-15 2015_12 viable FBgn0035627 Sse Separase http://flybase.net/reports/FBgn0035627.html FBgn0002461 protein_coding_gene 0008233=peptidase activity "0022008=neurogenesis, 0000070=mitotic sister chromatid segregation, 0006909=phagocytosis, 0007127=meiosis I, 0006508=proteolysis" 0005634=nucleus "lethal(3)SG14, separase, sse, CG10583, SSE, l(3)13m-281, l(3)SG14" "IPR030397=SEPARIN core domain, IPR005314=Peptidase C50, separase" CG10583 16-Dec-15 2015_12 "mitotic cell cycle defective,viable,fertile,lethal,recessive,somatic clone,lethal - all die before end of larval stage,some die during larval stage,wild-type,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "mitotic cell cycle,embryonic/larval brain,somatic clone,embryonic/larval neuroblast,mitotic cell cycleSseA),imaginal disc,cell cycle,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC09746 E -0.772159165 0.474464403 1.269786476 -1.625495694 -0.067193321 -1.04068294 FBgn0029512 Aos1 Activator of SUMO 1 http://flybase.net/reports/FBgn0029512.html "FBgn0038048, FBgn0040288" protein_coding_gene "0031624=ubiquitin conjugating enzyme binding, 0008641=small protein activating enzyme activity, 0033134=ubiquitin activating enzyme binding, 0019948=SUMO activating enzyme activity" "0016925=protein sumoylation, 0007346=regulation of mitotic cell cycle, 0019950=SMT3-dependent protein catabolic process, 0051092=positive regulation of NF-kappaB transcription factor activity, 0022008=neurogenesis" "0005634=nucleus, 0031510=SUMO activating enzyme complex" "SAE1, Dmaos1, DmAos1, Smt3 activating enzyme 1, Sae1, CG12276, Aos1, AOS1, DmSae1, DmSAE1, Aos, Ubiquitin activating enzyme 1, Ubiquitin activating enzyme" "IPR016040=NAD(P)-binding domain, IPR000594=THIF-type NAD/FAD binding fold, IPR000011=Ubiquitin/SUMO-activating enzyme E1" CG12276 16-Dec-15 2015_12 ENSDARG00000010487(sae1) ENSXETG00000000161(SAE1) ENSMUSG00000052833(Sae1) ENSG00000142230(SAE1) "developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,melanotic mass phenotype,increased cell death,somatic clone,cell lethal,decreased cell number,somatic clone - Minute background,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal,neuroanatomy defective,partially lethal - majority die,visible" "imaginal disc,embryonic/larval optic lobe,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,eye,eye disc,adult head" FBgn0035088 CG3776 http://flybase.net/reports/FBgn0035088.html FBgn0022215 protein_coding_gene 0005515=protein binding 0005739=mitochondrion "Drosophila P29, P29, CG3776, EP(2)0835, DmP29, Juvenile hormone esterase binding protein 29, Jhebp29" CG3776 16-Dec-15 2015_12 "ENSDARG00000069671(zgc:123096),ENSDARG00000035783" WBGene00044745(Y62E10A.20) ENSMUSG00000025971(9430016H08Rik) ENSG00000162972(C2orf47) "visible,partially lethal - majority die,some die during pupal stage,female fertile,short lived,male,female,male fertile,female sterile,heat sensitive,lethal,small body,courtship behavior defective,locomotor behavior defective" "trichogen cell,mesothoracic tergum" FBgn0259468 C345 http://flybase.net/reports/FBgn0259468.html gene 16-Dec-15 2015_12 "visible,lethal" "wing hair,chaeta" FBgn0000887 fs(1)M85 female sterile (1) M85 http://flybase.net/reports/FBgn0000887.html gene 16-Dec-15 2015_12 "female sterile,recessive,lethal,maternal effect" FBgn0020847 l(1)3Db lethal (1) 3Db http://flybase.net/reports/FBgn0020847.html gene X1 16-Dec-15 2015_12 "lethal,recessive" "external sensory organ,multidendritic neuron,axon" FBgn0002946 nob no bridge http://flybase.net/reports/FBgn0002946.html gene 0007628=adult walking behavior "no protocerebral bridge, no-bridge" 16-Dec-15 2015_12 "short lived,female sterile,recessive,lethal,female,partially,viable,male,uncoordinated,memory defective,behavior defective,locomotor behavior defective" "protocerebral bridge,protocerebral bridge slice,fan-shaped body" FBgn0034997 CG3376 http://flybase.net/reports/FBgn0034997.html protein_coding_gene 0004767=sphingomyelin phosphodiesterase activity 0006685=sphingomyelin catabolic process aSMase "IPR011160=Sphingomyelin phosphodiesterase, IPR011001=Saposin-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR008139=Saposin B type domain, IPR029052=Metallo-dependent phosphatase-like" CG3376 16-Dec-15 2015_12 WBGene00000212(asm-2) ENSMUSG00000037049(Smpd1) ENSG00000166311(SMPD1) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0000520 dwg deformed wings http://flybase.net/reports/FBgn0000520.html "FBgn0003974, FBgn0024976, FBgn0026052" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043035=chromatin insulator sequence binding, 0005515=protein binding, 0008270=zinc ion binding" "0005634=nucleus, 0000790=nuclear chromatin" "zeste-white 5, CG2711, scs-binding protein, DWG, zw5, zeste-white5, l(1)zw5, Zw5, deformed wing, Zw-5, l(1)3Be, ZW-5, zw-5, ZW5, ves, Sbp, CG2714, Deformed wings, scs binding protein, EG:95B7.6, vestigium, SBP" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR012934=Zinc finger, AD-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG2711 16-Dec-15 2015_12 "YPR015C(),YPR013C()" WBGene00006970(zag-1) "lethal,recessive,wild-type,viable,reduced,male sterile,visible,male,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,polyphasic,cell lethal,germline clone" "wing,eye,wing vein,macrochaeta,pigment cell,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,ocellar bristle,anterior vertical bristle,posterior vertical bristle,vibrissae" FBgn0039492 CG6051 http://flybase.net/reports/FBgn0039492.html protein_coding_gene 0046872=metal ion binding "blade runner 2, blr2" "IPR017455=Zinc finger, FYVE-related, IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000306=FYVE zinc finger" CG6051 16-Dec-15 2015_12 ENSDARG00000060430(zfyve28) WBGene00003084(lst-2) "ENSXETG00000020484(ZFYVE28),ENSXETG00000007237()" ENSMUSG00000037224(Zfyve28) ENSG00000159733(ZFYVE28) "lethal - all die before end of larval stage,viable,visible" "embryonic/larval muscle system,mesothoracic tergum" DRSC15956 E -0.165553119 0.91878573 0.315818125 -3.043237715 -1.463975992 -0.699439704 FBgn0004646 ogre optic ganglion reduced http://flybase.net/reports/FBgn0004646.html "FBgn0000265, FBgn0002988, FBgn0029926" protein_coding_gene 0005243=gap junction channel activity "0007399=nervous system development, 0010496=intercellular transport, 0007602=phototransduction, 0007632=visual behavior" "0005921=gap junction, 0016021=integral component of membrane, 0016323=basolateral plasma membrane, 0005886=plasma membrane" "Innexin 1, l(1)jnL3, Dm-inx1, CB8, FBpp0070995, jnL3, inx1, Inx1, contrast-blind-8, l(1)ogre, inx-1, optic ganglia-reduced, CG3039, Ogre, l(1)6Ec, innexin-1, cb-8, Optic ganglion reduced, innexin 1" IPR000990=Innexin CG3039 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" "viable,fertile,wild-type,lethal,recessive,heat sensitive,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,cell lethal,germline clone" "optic lobe,central nervous system,lamina monopolar neuron,photoreceptor cell" FBgn0259958 Sfp24F Seminal fluid protein 24F http://flybase.net/reports/FBgn0259958.html protein_coding_gene 0030246=carbohydrate binding 0032504=multicellular organism reproduction 0005615=extracellular space "Seminal fluid protein 24F, SFP24F, CG42468" "IPR016187=C-type lectin fold, IPR001304=C-type lectin, IPR016186=C-type lectin-like" CG42468 16-Dec-15 2015_12 "ENSDARG00000059261(LOC100333431),ENSDARG00000068178,ENSDARG00000012263(si:ch73-343l4.8),ENSDARG00000071218,ENSDARG00000025547,ENSDARG00000071219(illr2),ENSDARG00000059254(illr1),ENSDARG00000018327(illr3),ENSDARG00000025150,ENSDARG00000069322,ENSDARG00000043894,ENSDARG00000055817,ENSDARG00000029461,ENSDARG00000057091,ENSDARG00000045511,ENSDARG00000008182,ENSDARG00000032346,ENSDARG00000039636,ENSDARG00000069323,ENSDARG00000069226,ENSDARG00000026805,ENSDARG00000057090,ENSDARG00000057092,ENSDARG00000042136,ENSDARG00000070106(LOC100331932)" "ENSXETG00000000644(),ENSXETG00000021878(),ENSXETG00000000646(),ENSXETG00000026809(),ENSXETG00000023911()" "ENSMUSG00000040197(Cd209e),ENSMUSG00000040165(Cd209c),ENSMUSG00000031494(Cd209a),ENSMUSG00000065987(Cd209b),ENSMUSG00000079168(Cd209g),ENSMUSG00000074491(Clec4g),ENSMUSG00000030142(Clec4e),ENSMUSG00000051906(Cd209f),ENSMUSG00000071158(Gm156),ENSMUSG00000030158(Clec12b)" "ENSG00000166527(CLEC4D),ENSG00000205846(CLEC6A),ENSG00000166523(CLEC4E),ENSG00000141505(ASGR1)" FBgn0034214 CG6550 http://flybase.net/reports/FBgn0034214.html protein_coding_gene "0016740=transferase activity, 0051539=4 iron, 4 sulfur cluster binding" 0009451=RNA modification 0012505=endomembrane system "IPR005839=Methylthiotransferase, IPR013848=Methylthiotransferase, N-terminal, IPR023970=Methylthiotransferase/radical SAM-type protein, IPR023404=Radical SAM, alpha/beta horseshoe, IPR002792=TRAM domain, IPR006638=Elongator protein 3/MiaB/NifB, IPR007197=Radical SAM, IPR020612=Methylthiotransferase, conserved site, IPR006466=MiaB-like tRNA modifying enzyme, archaeal-type" CG6550 16-Dec-15 2015_12 WBGene00022363(Y92H12BL.1) ENSXETG00000000022(cdkal1) ENSMUSG00000006191(Cdkal1) ENSG00000145996(CDKAL1) viable DRSC07001 I 1.867450901 -0.315624744 1.406763782 0.217958622 -1.32892967 -0.424364494 FBgn0039589 CG9986 http://flybase.net/reports/FBgn0039589.html protein_coding_gene IPR019311=Protein of unknown function DUF2362 CG9986 16-Dec-15 2015_12 ENSDARG00000060987(zgc:154077) WBGene00008339(C55A6.10) ENSXETG00000005966(BC079954.1) ENSMUSG00000030347(D6Wsu163e) ENSG00000047621(C12orf4) "viable,fertile" FBgn0010263 Rbp9 RNA-binding protein 9 http://flybase.net/reports/FBgn0010263.html "FBgn0010253, FBgn0031482" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0003723=RNA binding, 0003730=mRNA 3'-UTR binding" "0007293=germarium-derived egg chamber formation, 0060856=establishment of blood-brain barrier, 0036093=germ cell proliferation, 0048477=oogenesis" 0005634=nucleus "rbp9, female sterile(2)Bridges, rbp9a, fs(2)B, RBP9-2, rrm9, rbp, RRM9, CG3151, CG15402, fes, rrm10, RRM10, Rpb9, RNA binding protein 9, Arrest, female sterile, RNA-binding protein 10, RBP9, Rbp10, female sterile (2) Bridges" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006548=Splicing factor ELAV/HuD, IPR002343=Paraneoplastic encephalomyelitis antigen, IPR000504=RNA recognition motif domain" CG3151 16-Dec-15 2015_12 "ENSDARG00000040732(zgc:91918),ENSDARG00000045639(elavl4),ENSDARG00000014420(elavl3),ENSDARG00000038695(elavl1),ENSDARG00000016405(hug)" YCL011C(GBP2) WBGene00001368(exc-7) "ENSXETG00000008680(ELAVL4),ENSXETG00000016741(elval3),ENSXETG00000009387(ELAVL2),ENSXETG00000008752(elavl1)" "ENSMUSG00000008489(Elavl2),ENSMUSG00000028546(Elavl4),ENSMUSG00000003410(Elavl3),ENSMUSG00000040028(Elavl1)" "ENSG00000107105(ELAVL2),ENSG00000162374(ELAVL4),ENSG00000196361(ELAVL3),ENSG00000066044(ELAVL1)" " larval stage | third instar , pupal stage && adult stage "

" pupal stage && adult stage , adult stage , pupal stage | late " " thoracico-abdominal ganglion

, antenna

, cell body &&of lamina

, cell body &&of adult brain

" "viable,female sterile,locomotor behavior defective,conditional,short lived,partially,wild-type,recessive,lethal,partially lethal - majority die,visible,body color defective" "ovariole,cystocyte,egg chamber,germarium,nurse cell,fusome,mesothoracic tergum" FBgn0032078 C1GalTA Core 1 Galactosyltransferase A http://flybase.net/reports/FBgn0032078.html FBgn0044521 protein_coding_gene "0048531=beta-1,3-galactosyltransferase activity, 0016263=glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity" "0021551=central nervous system morphogenesis, 0051489=regulation of filopodium assembly, 0009247=glycolipid biosynthetic process, 0016267=O-glycan processing, core 1, 0006486=protein glycosylation, 1902037=negative regulation of hematopoietic stem cell differentiation" 0016021=integral component of membrane "dC1GalT1, C1GALT1, C1GalTA, Core 1 Galactosyltransferase A, C1beta3GalT1, unnamed, core 1 beta1,3-galactosyltransferase, dC1beta3GalT1, anon-WO0144478.18, CG9520" IPR003378=Fringe-like CG9520 16-Dec-15 2015_12 "ENSDARG00000055585(c1galt1a),ENSDARG00000055561(c1galt1b)" WBGene00008019(C38H2.2) "ENSXETG00000007295(C1GALT1),ENSXETG00000006215(),ENSXETG00000009666(),ENSXETG00000025171()" ENSMUSG00000042460(C1galt1) ENSG00000106392(C1GALT1) "viable,fertile,lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,partially" "ventral nerve cord,embryonic/larval brain,leg,plasmatocyte" FBgn0035498 Fit1 Fermitin 1 http://flybase.net/reports/FBgn0035498.html FBgn0062020 protein_coding_gene 0050839=cell adhesion molecule binding "0050829=defense response to Gram-negative bacterium, 0007160=cell-matrix adhesion, 0048738=cardiac muscle tissue development" 0005737=cytoplasm "fermitin 1, anon-WO0118547.421, fit 1, CG14991" "IPR001849=Pleckstrin homology domain, IPR019749=Band 4.1 domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019748=FERM central domain" CG14991 16-Dec-15 2015_12 "ENSDARG00000052652(LOC100332544),ENSDARG00000020242(fermt2),ENSDARG00000030938(zgc:64101)" WBGene00006836(unc-112) "ENSXETG00000005517(FERMT1),ENSXETG00000027692(plekhc1)" "ENSMUSG00000037712(Fermt2),ENSMUSG00000027356(Fermt1),ENSMUSG00000024965(Fermt3)" "ENSG00000073712(FERMT2),ENSG00000101311(FERMT1),ENSG00000149781(FERMT3)" "some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053002 mRpL27 mitochondrial ribosomal protein L27 http://flybase.net/reports/FBgn0053002.html protein_coding_gene 0003735=structural constituent of ribosome "0032543=mitochondrial translation, 0006412=translation" 0005762=mitochondrial large ribosomal subunit "CG33002, Ribosomal protein L27A, CG15442" IPR001684=Ribosomal protein L27 CG33002 16-Dec-15 2015_12 ENSDARG00000032985(LOC100329921) ENSXETG00000027422(MRPL27) "ENSMUSG00000024414(Mrpl27),ENSMUSG00000071867(Gm6304)" ENSG00000108826(MRPL27) "viable,visible" trichogen cell FBgn0026179 siz schizo http://flybase.net/reports/FBgn0026179.html "FBgn0037047, FBgn0037048, FBgn0037049, FBgn0052434" protein_coding_gene "0045296=cadherin binding, 0005086=ARF guanyl-nucleotide exchange factor activity, 0005085=guanyl-nucleotide exchange factor activity" "0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior, 0007417=central nervous system development, 0016192=vesicle-mediated transport, 0030036=actin cytoskeleton organization, 0032012=regulation of ARF protein signal transduction, 0007520=myoblast fusion" "0030054=cell junction, 0005802=trans-Golgi network, 0005634=nucleus" "loner, schizo, Schizo, Loner, CG12981, CG32434, dBRAG, CG12980, CG10577" "IPR023394=Sec7 domain, alpha orthogonal bundle, IPR000048=IQ motif, EF-hand binding site, IPR000904=Sec7 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain" CG32434 16-Dec-15 2015_12 ENSDARG00000016551(LOC100148736) WBGene00019726(M02B7.5) "ENSXETG00000007177(IQSEC2),ENSXETG00000003631(IQSEC3)" "ENSMUSG00000034312(Iqsec1),ENSMUSG00000041115(Iqsec2),ENSMUSG00000040797(Iqsec3)" "ENSG00000144711(IQSEC1),ENSG00000124313(IQSEC2),ENSG00000120645(IQSEC3)" "behavior defective,recessive,viable,fertile,lethal" "ventral nerve cord commissure,commissure,midline glial cell,longitudinal connective,embryonic myoblast,fusion competent cell" FBgn0033113 Spn42Dc Serpin 42Dc http://flybase.net/reports/FBgn0033113.html protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0010951=negative regulation of endopeptidase activity, 0030162=regulation of proteolysis, 0045861=negative regulation of proteolysis" 0005615=extracellular space CG9455 "IPR000215=Serpin family, IPR023795=Serpin, conserved site, IPR023796=Serpin domain" CG9455 16-Dec-15 2015_12 "ENSMUSG00000045827(Serpinb9),ENSMUSG00000021403(Serpinb9b),ENSMUSG00000062342(Serpinb9e),ENSMUSG00000038327(Serpinb9f),ENSMUSG00000054266(Serpinb9d),ENSMUSG00000071452(Gm11397),ENSMUSG00000057726(Serpinb9g),ENSMUSG00000021404(Serpinb9c),ENSMUSG00000060147(Serpinb6a),ENSMUSG00000026315(Serpinb8),ENSMUSG00000042842(Serpinb6b),ENSMUSG00000052180(Serpinb6c),ENSMUSG00000047889(Serpinb6d),ENSMUSG00000069248(Serpinb6e)" "visible,viable" "wing vein,ectopic" DRSC05010 IE 4.669816785 1.259618237 1.704465548 0.475985309 -0.428844766 0.01895451 FBgn0267912 CanA-14F Calcineurin A at 14F http://flybase.net/reports/FBgn0267912.html "FBgn0030758, FBgn0005782, FBgn0086544" protein_coding_gene 0004722=protein serine/threonine phosphatase activity "0006470=protein dephosphorylation, 0051533=positive regulation of NFAT protein import into nucleus, 0030431=sleep" "DmCanA-14F, PP2B, PpD27, protein phosphatase from PCR fragment D27, canA-14F, CnnA14D(I), CG9819, Protein phosphatase D27, Calcineurin, mRNA-like ncRNA in embryogenesis 12, MRE12, calcineurin A at 14F, unnamed, calcineurin, D27, Calcineurin A at 14F, CnnA14D" "IPR029052=Metallo-dependent phosphatase-like, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG9819 16-Dec-15 2015_12 "ENSDARG00000004988,ENSDARG00000057456(zgc:158685)" "YML057W(CMP2),YLR433C(CNA1)" WBGene00006527(tax-6) "ENSXETG00000011160(PPP3CA),ENSXETG00000010644(PPP3CB),ENSXETG00000010528(PPP3CC)" "ENSMUSG00000028161(Ppp3ca),ENSMUSG00000021816(Ppp3cb)" "ENSG00000138814(PPP3CA),ENSG00000107758(PPP3CB),ENSG00000120910(PPP3CC)" "viable,fertile,sleep defective,locomotor behavior defective,lethal,heat sensitive,hyperactive" FBgn0037465 CG1105 http://flybase.net/reports/FBgn0037465.html protein_coding_gene "IPR014756=Immunoglobulin E-set, IPR011022=Arrestin C-terminal-like domain, IPR011021=Arrestin-like, N-terminal" CG1105 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" WBGene00011732(T12D8.4) "ENSXETG00000013606(ARRDC2),ENSXETG00000018085(arrdc3),ENSXETG00000002108(ARRDC4),ENSXETG00000011050(TXNIP)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" "ENSG00000105643(ARRDC2),ENSG00000113369(ARRDC3),ENSG00000140450(ARRDC4),ENSG00000117289(TXNIP)" "viable,visible" trichogen cell FBgn0027565 CG5498 http://flybase.net/reports/FBgn0027565.html protein_coding_gene 0008565=protein transporter activity "0016197=endosomal transport, 0007034=vacuolar transport" 0000815=ESCRT III complex "BcDNA:GH08385, transcript 2" IPR005024=Snf7 family CG5498 16-Dec-15 2015_12 ENSDARG00000041362(chmp7) WBGene00011976(T24B8.2) ENSXETG00000016810(CHMP7_XENTR) ENSMUSG00000034190(Chmp7) ENSG00000147457(CHMP7) viable FBgn0035059 CG3894 http://flybase.net/reports/FBgn0035059.html FBgn0035058 protein_coding_gene 0035556=intracellular signal transduction "CG9197, dmNeural-like" "IPR001496=SOCS box domain, IPR006573=NEUZ domain" CG3894 16-Dec-15 2015_12 ENSDARG00000062446(zgc:162187) ENSXETG00000014872(NEURL2) ENSMUSG00000039873(Neurl2) ENSG00000124257(NEURL2) viable DRSC04429 I 1.807363843 -0.673355481 1.115252206 0.750739778 -0.590153373 0.21405395 FBgn0004864 hop hopscotch http://flybase.net/reports/FBgn0004864.html "FBgn0001211, FBgn0003895, FBgn0022799" protein_coding_gene "0004713=protein tyrosine kinase activity, 0004672=protein kinase activity, 0004715=non-membrane spanning protein tyrosine kinase activity, 0005524=ATP binding" "0016476=regulation of embryonic cell shape, 0042067=establishment of ommatidial planar polarity, 0048103=somatic stem cell division, 0008283=cell proliferation, 0007424=open tracheal system development, 0060031=mediolateral intercalation, 0006468=protein phosphorylation, 0006959=humoral immune response, 0006952=defense response, 0042386=hemocyte differentiation, 0019827=stem cell maintenance, 0048477=oogenesis, 0035206=regulation of hemocyte proliferation, 0051607=defense response to virus, 0007530=sex determination, 0006955=immune response, 0007538=primary sex determination, 0035172=hemocyte proliferation, 0045475=locomotor rhythm, 0007455=eye-antennal disc morphogenesis, 0048749=compound eye development, 0007260=tyrosine phosphorylation of STAT protein, 0030707=ovarian follicle cell development, 0006968=cellular defense response, 0001745=compound eye morphogenesis, 0045610=regulation of hemocyte differentiation, 0007350=blastoderm segmentation, 0007616=long-term memory, 0030713=ovarian follicle cell stalk formation, 0007399=nervous system development, 0042078=germ-line stem cell division, 0007480=imaginal disc-derived leg morphogenesis, 0007262=STAT protein import into nucleus, 0035010=encapsulation of foreign target, 0007365=periodic partitioning, 0007298=border follicle cell migration, 0016318=ommatidial rotation, 0045317=equator specification, 0035167=larval lymph gland hemopoiesis, 0035171=lamellocyte differentiation, 0007476=imaginal disc-derived wing morphogenesis, 0007442=hindgut morphogenesis, 0003383=apical constriction, 0046425=regulation of JAK-STAT cascade, 0007259=JAK-STAT cascade, 0001751=compound eye photoreceptor cell differentiation, 0030097=hemopoiesis" "0005856=cytoskeleton, 0005737=cytoplasm" "HOPSCOTCH, DmHD-160, l(1)L4, d-jak, Hop1, jak, l(1)G18, Jak, JAK kinase, Hop, JAK, Janus-family kinase, hopscotch, Hopscotch, 4, Tum-1, l(1)10Be, Janus kinase, l(1)hop, CG1594, Tumorous, Dm JAK, msvl, HD-160, hop/JAK, L4, Hopskotch, locus 18, HOP, Tum" "IPR000980=SH2 domain, IPR017441=Protein kinase, ATP binding site, IPR019749=Band 4.1 domain, IPR008266=Tyrosine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000299=FERM domain" CG1594 16-Dec-15 2015_12 "ENSDARG00000010252(jak3),ENSDARG00000018882,ENSDARG00000020625(jak1),ENSDARG00000020326" "ENSXETG00000000586(JAK2),ENSXETG00000011623(TYK2),ENSXETG00000020396(JAK1)" "ENSMUSG00000024789(Jak2),ENSMUSG00000031805(Jak3),ENSMUSG00000028530(Jak1),ENSMUSG00000032175(Tyk2)" "ENSG00000096968(JAK2),ENSG00000105639(JAK3),ENSG00000162434(JAK1),ENSG00000105397(TYK2)" " embryonic stage | early , embryonic stage -- adult stage " "lethal,recessive,heat sensitive,female sterile,visible,planar polarity defective,maternal effect,polyphasic,male sterile,memory defective,RU486 conditional,lethal - all die before end of larval stage,some die during larval stage,dominant,viable,rescuable maternal effect,wild-type,cell non-autonomous,somatic clone,cell autonomous,cell shape defective,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,immune response defective,partially,fertile,female,reduced,locomotor rhythm defective,partially lethal - majority die,melanotic mass phenotype,tumorigenic,semidominant,increased cell number,hyperplasia,neuroanatomy defective" "eye,ommatidium,interommatidial bristle,eye photoreceptor cell,testis,axoneme,wing vein,ectopic,polar follicle cell,supernumerary,egg chamber,pole cell,maternal effect,gonad,embryonic hindgut,germline clone,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,mesothoracic ventral denticle belt,embryonic abdominal segment 5,non-rescuable maternal effect,embryonic abdominal segment 4,presumptive embryonic/larval tracheal system,embryonic head,telson,border follicle cell,somatic clone,nurse follicle cell,spermatogonium,male germline stem cell,embryonic/larval proventriculus,denticle belt,rescuable maternal effect,tracheal branch primordium,dorsal trunk primordium,cell non-autonomous,eye equator,ectoderm,centripetally migrating follicle cell,oocyte associated follicle cell,follicle cell,posterior,interfollicle cell,cyst progenitor cell,embryonic/larval hemocyte,embryonic/larval lymph gland,gastric caecum,embryonic/larval foregut,embryonic/larval midgut,embryonic/larval hindgut,embryonic/larval brain,embryonic/larval anterior spiracle,embryonic/larval fat body,melanotic mass,segment,embryonic abdominal segment,filzkorper,plasmatocyte,hemocyte,lamellocyte,hindgut,hindgut & nucleus,peripheral nervous system,axon,crystal cell,podocyte,heat sensitive,precursor,abdomen,tracheal pit,ovary,hindgut & nucleushs.PB,axonhs.PB,wing,scutellum,scutum,larval outer optic anlage,male germline cell" FBgn0029688 lva lava lamp http://flybase.net/reports/FBgn0029688.html protein_coding_gene "0030507=spectrin binding, 0008017=microtubule binding, 0005515=protein binding, 0003779=actin binding" "0048812=neuron projection morphogenesis, 0050775=positive regulation of dendrite morphogenesis, 0007349=cellularization, 0051683=establishment of Golgi localization" "0000137=Golgi cis cisterna, 0005875=microtubule associated complex, 0005938=cell cortex, 0005794=Golgi apparatus" "Lva, LVA, Lava-Lamp, CG6450, Lava Lamp, LAVA LAMP, LVA_DROME, actin-binding protein 2, Lvl, Lava, CG#6450, ABP2, Lavalamp, lvl, Lava lamp, lava" CG6450 16-Dec-15 2015_12 "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "Golgi apparatus & dendritic arborising neuron477,dendrite & dendritic arborising neuron477,Golgi apparatus & dendritic arborising neuron109(2)80,dendrite & dendritic arborising neuron109(2)80" DRSC18403 E 1.037045854 0.385096231 1.069402125 -1.785426693 -0.362481296 -0.242524481 FBgn0000662 fl(2)d female lethal d http://flybase.net/reports/FBgn0000662.html FBgn0028976 protein_coding_gene 0005515=protein binding "0019099=female germ-line sex determination, 0046331=lateral inhibition, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007539=primary sex determination, soma, 0000375=RNA splicing, via transesterification reactions, 0007530=sex determination, 0048749=compound eye development" 0005634=nucleus "v(2)k16105, female-lethal(2)d, CG6315" IPR029732=Pre-mRNA-splicing regulator WTAP CG6315 16-Dec-15 2015_12 ENSDARG00000042642(wtap) ENSMUSG00000060475(Wtap) ENSG00000146457(WTAP) " larval stage , embryonic stage , adult stage | female , adult stage | male " " adult stage | female , embryonic stage , adult stage | male , larval stage | female , larval stage | male " " adult head

,

, ovary

" "visible,recessive,lethal,wild-type,female,heat sensitive,partially lethal - majority die,male,partially,female sterile,lethal - all die before end of larval stage,some die during larval stage,sex-determination defective,somatic clone,some die during pupal stage" "eye,somatic clone,chaeta,supernumerary,mesothoracic tergum,eye photoreceptor cell,rhabdomere of eye photoreceptor cell" FBgn0004511 dy dusky http://flybase.net/reports/FBgn0004511.html FBgn0000525 protein_coding_gene "0007476=imaginal disc-derived wing morphogenesis, 0000902=cell morphogenesis" "0016021=integral component of membrane, 0005886=plasma membrane" "CG9355, alae parvae, dy1, ala" IPR001507=Zona pellucida domain CG9355 16-Dec-15 2015_12 WBGene00001063(dpy-1) " embryonic stage , pupal stage , larval stage | second instar , larval stage | first instar " "viable,fertile,visible,recessive,male fertile,female fertile,heat sensitive,cell autonomous,somatic clone,lethal,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heat sensitive,cell autonomous,somatic clone,antenna,microchaeta,chaeta" FBgn0046124 E(To)10 E(To)10 http://flybase.net/reports/FBgn0046124.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0001316 klar klarsicht http://flybase.net/reports/FBgn0001316.html FBgn0002650 protein_coding_gene "0019894=kinesin binding, 0005515=protein binding" "0051647=nucleus localization, 0060361=flight, 0031887=lipid particle transport along microtubule, 0040011=locomotion, 0007097=nuclear migration, 0006869=lipid transport, 0035239=tube morphogenesis, 0032386=regulation of intracellular transport, 0061024=membrane organization, 0034453=microtubule anchoring, 0035149=lumen formation, open tracheal system, 0007523=larval visceral muscle development, 0042051=compound eye photoreceptor development, 0045855=negative regulation of pole plasm oskar mRNA localization, 0006997=nucleus organization, 0001745=compound eye morphogenesis" "0005737=cytoplasm, 0005811=lipid particle, 0048471=perinuclear region of cytoplasm, 0005640=nuclear outer membrane, 0005635=nuclear envelope, 0016021=integral component of membrane, 0005881=cytoplasmic microtubule" "Klarischt, marbles, Klarsicht, kls, marb, Klar, CG17046" IPR012315=KASH domain CG17046 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage | late " " eye disc

, adult salivary gland primordium

dorsal & posterior , morphogenetic furrow | posterior to

" larval stage | third instar photoreceptor

"locomotor behavior defective,flightless,viable,fertile,visible,recessive,female semi-sterile,wild-type,partially lethal - majority die,some die during pupal stage,neuroanatomy defective" "embryonic/larval muscle system,A1-7 dorsal oblique muscle 1,A1-7 dorsal oblique muscle 2,A1-7 dorsal acute muscle 1,A1-7 dorsal acute muscle 2,oocyte nucleus,photoreceptor cell,eye,rhabdomereemc-E12),photoreceptor cell & nucleusemc-E12),rhabdomere,photoreceptor cell & nucleus,retina,interommatidial bristle,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,nucleus & eye photoreceptor cell & eye disc,nucleus & cone cell & eye disc,cone cell,eye photoreceptor cell,lipid particle,ommatidium,presumptive embryonic salivary gland,eye disc,tracheal system,scutum & macrochaeta,eye disc & nucleus | ectopic,rhabdomere & nucleus,chaeta,supernumerary,neurite | pharate adult stage" FBgn0004656 fs(1)h female sterile (1) homeotic http://flybase.net/reports/FBgn0004656.html "FBgn0000809, FBgn0001447, FBgn0025246, FBgn0025884, FBgn0040137, FBgn0040199" protein_coding_gene "0004672=protein kinase activity, 0003677=DNA binding" "0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0007362=terminal region determination, 0045892=negative regulation of transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter, 0007476=imaginal disc-derived wing morphogenesis" 0005634=nucleus "Fs(1)h, Fs(1)hS, rancor, clone 1.81, fs(1)M16, female sterile (1) homoeotic, ORE-1, Fsh, l(1)7Da, fs(1)26/26A, l(1)G0495, anon-fast-evolving-1G2, CG2252, fst(1)h, anon-EST:fe1G2, fsh, fs(1)1456, rnc, female sterile homeotic, l(1)G0093, N72, fs(1)R10.4, Fs(1)hL, anon-EST:Liang-1.81" "IPR027353=NET domain, IPR018359=Bromodomain, conserved site, IPR001487=Bromodomain" CG2252 16-Dec-15 2015_12 "ENSDARG00000022280(brd2a),ENSDARG00000035126(brd3b),ENSDARG00000006527(brd3a)" "YDL070W(BDF2),YLR399C(BDF1)" WBGene00022473(bet-1) ENSMUSG00000024002(Brd4) ENSG00000141867(BRD4) "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,male,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,heat sensitive,maternal effect,cell lethal,germline clone,rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,partially" "hypostomal sclerite,mouth hooks,embryonic head,abdominal segment 2,maternal effect,heat sensitive,filzkorper,larval head,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,egg,metathoracic segment" DRSC29017 K -0.156750498 0.260578013 0.052372009 0.336929708 3.384193892 3.931450316 FBgn0016675 Lectin-galC1 Galactose-specific C-type lectin http://flybase.net/reports/FBgn0016675.html protein_coding_gene "0004872=receptor activity, 0030246=carbohydrate binding, 0005534=galactose binding" "0043152=induction of bacterial agglutination, 0006952=defense response, 0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" 0005576=extracellular region "galactin, lectin-galC1, Lecti-galC1, DL1, galactose specific C-type lectin, AC007082a, lectin, Dgal-1, CG9976, Drosophila lectin 1" "IPR016186=C-type lectin-like, IPR001304=C-type lectin, IPR016187=C-type lectin fold" CG9976 16-Dec-15 2015_12 "ENSDARG00000059261(LOC100333431),ENSDARG00000068178,ENSDARG00000012263(si:ch73-343l4.8),ENSDARG00000071218,ENSDARG00000025547,ENSDARG00000071219(illr2),ENSDARG00000059254(illr1),ENSDARG00000018327(illr3),ENSDARG00000025150,ENSDARG00000069322,ENSDARG00000043894,ENSDARG00000055817,ENSDARG00000029461,ENSDARG00000057091,ENSDARG00000045511,ENSDARG00000008182,ENSDARG00000032346,ENSDARG00000039636,ENSDARG00000069323,ENSDARG00000069226,ENSDARG00000026805,ENSDARG00000057090,ENSDARG00000057092,ENSDARG00000042136,ENSDARG00000070106(LOC100331932)" "ENSXETG00000000644(),ENSXETG00000021878(),ENSXETG00000000646(),ENSXETG00000026809(),ENSXETG00000023911()" "ENSMUSG00000040197(Cd209e),ENSMUSG00000040165(Cd209c),ENSMUSG00000031494(Cd209a),ENSMUSG00000065987(Cd209b),ENSMUSG00000079168(Cd209g),ENSMUSG00000074491(Clec4g),ENSMUSG00000030142(Clec4e),ENSMUSG00000051906(Cd209f),ENSMUSG00000071158(Gm156),ENSMUSG00000030158(Clec12b)" "ENSG00000166527(CLEC4D),ENSG00000205846(CLEC6A),ENSG00000166523(CLEC4E),ENSG00000141505(ASGR1)" " adult stage , pupal stage , larval stage | third instar " viable FBgn0038870 Oga O-GlcNAcase http://flybase.net/reports/FBgn0038870.html protein_coding_gene "0004415=hyalurononglucosaminidase activity, 0004402=histone acetyltransferase activity" "0006491=N-glycan processing, 0045475=locomotor rhythm" "CG5871, OGA, GlcNAcase, MGEA5" "IPR017853=Glycoside hydrolase superfamily, IPR011496=Beta-N-acetylglucosaminidase, IPR016181=Acyl-CoA N-acyltransferase" CG5871 16-Dec-15 2015_12 WBGene00020596(oga-1) ENSXETG00000014468(MGEA5) ENSMUSG00000025220(Mgea5) ENSG00000198408(MGEA5) "locomotor rhythm defective,large body,viable" FBgn0261698 CG42732 http://flybase.net/reports/FBgn0261698.html "FBgn0261685, FBgn0085392, FBgn0033510, FBgn0040771, FBgn0033517, FBgn0033513" protein_coding_gene "0015269=calcium-activated potassium channel activity, 0005267=potassium channel activity" "0048812=neuron projection morphogenesis, 0006813=potassium ion transport, 0022008=neurogenesis" 0016020=membrane "Dm_2R:24301, CG12899, CG12900/CG34363, CG34363, CG12897, Dm_2R:24438, CG12901, Slack, CG12904" "IPR013099=Potassium channel domain, IPR016040=NAD(P)-binding domain, IPR003929=Potassium channel, calcium-activated, BK, alpha subunit" CG42732 16-Dec-15 2015_12 WBGene00004831(slo-2) "ENSXETG00000003449(KCNT1),ENSXETG00000002262(KCNT2)" "ENSMUSG00000058740(Kcnt1),ENSMUSG00000052726(Kcnt2)" "ENSG00000107147(KCNT1),ENSG00000162687(KCNT2)" DRSC23225 K 0.044615677 1.771277296 FBgn0030914 CG6106 http://flybase.net/reports/FBgn0030914.html protein_coding_gene "0050897=cobalt ion binding, 0008270=zinc ion binding, 0004038=allantoinase activity" 0000256=allantoin catabolic process "IPR017593=Allantoinase, IPR006680=Amidohydrolase-related, IPR011059=Metal-dependent hydrolase, composite domain" CG6106 16-Dec-15 2015_12 ENSDARG00000038293(zgc:103559) YIR027C(DAL1) ENSXETG00000012148() viable FBgn0085397 Fili Fish-lips http://flybase.net/reports/FBgn0085397.html "FBgn0034669, FBgn0034668" protein_coding_gene "0042981=regulation of apoptotic process, 0007476=imaginal disc-derived wing morphogenesis" 0016021=integral component of membrane "CG34368, CG4054, CG13487, Fish-lips, CT32855, CT13464" "IPR003591=Leucine-rich repeat, typical subtype, IPR001611=Leucine-rich repeat" CG34368 16-Dec-15 2015_12 "ENSXETG00000015270(LINGO1),ENSXETG00000001552(LINGO2),ENSXETG00000013654(),ENSXETG00000002132(LINGO4)" "ENSG00000220008(LINGO3),ENSG00000174482(LINGO2),ENSG00000169783(LINGO1),ENSG00000213171(LINGO4)" FBgn0261053 Cad86C Cadherin 86C http://flybase.net/reports/FBgn0261053.html "FBgn0037840, FBgn0053112, FBgn0037839, FBgn0046765" protein_coding_gene 0005509=calcium ion binding "0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0044331=cell-cell adhesion mediated by cadherin, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0008360=regulation of cell shape" "0016021=integral component of membrane, 0035003=subapical complex, 0005887=integral component of plasma membrane" "BcDNA:LP07955, CG31425, CG4509, Cad86C, CG4655, CT14654, cadherin Cad86C, CG42601, CG31393, CG33112, CT15041, DCad86C" "IPR002126=Cadherin, IPR015919=Cadherin-like, IPR020894=Cadherin conserved site" CG42601 16-Dec-15 2015_12 "ENSDARG00000004643(cdhr1),ENSDARG00000044447,ENSDARG00000068586" "ENSXETG00000001875(PCDH1),ENSXETG00000022281(PCDH7),ENSXETG00000021181(PCDH9),ENSXETG00000002370(),ENSXETG00000007612(),ENSXETG00000011158(pcdh18),ENSXETG00000002683(),ENSXETG00000002703(),ENSXETG00000008792(BC074660.1),ENSXETG00000012808(PCDH20)" "ENSG00000165194(PCDH19),ENSG00000118946(PCDH17),ENSG00000189184(PCDH18),ENSG00000136099(PCDH8),ENSG00000102290(PCDH11X),ENSG00000169851(PCDH7)" FBgn0038307 mRpS10 mitochondrial ribosomal protein S10 http://flybase.net/reports/FBgn0038307.html FBgn0064933 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005763=mitochondrial small ribosomal subunit "MrpS10, BcDNA:GM25447, CG4247, Mitochondrial ribosomal protein S10, MRP-S10" IPR027486=Ribosomal protein S10 domain CG4247 16-Dec-15 2015_12 ENSDARG00000045913(si:ch211-51e12.6) WBGene00012556(Y37D8A.18) ENSXETG00000027052(MRPS10) ENSMUSG00000034729(Mrps10) ENSG00000048544(MRPS10) FBgn0027364 Six4 Six4 http://flybase.net/reports/FBgn0027364.html protein_coding_gene 0043565=sequence-specific DNA binding "0048812=neuron projection morphogenesis, 0007498=mesoderm development, 0007503=fat body development, 0006355=regulation of transcription, DNA-templated, 0007520=myoblast fusion, 0008406=gonad development" 0005634=nucleus "CG3871, myotonix, six4/5, six4, DSix4, Dsix4, D-six4, D-Six4" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG3871 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage 15 , embryonic stage | stage 9,10 " " embryonic brain

, procephalic segment

, organism | 80-90% egg length

, gonad

, mesoderm

, ventral nerve cord

" "viable,fertile,lethal,partially,recessive,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" "gonad,testis,ovary,crop,embryonic/larval muscle system,adult abdomen,germline cell,fat body/gonad primordium,embryonic somatic muscle,segment border muscle,ventral oblique muscle,ventral longitudinal muscle,border follicle cell,ectopic,somatic clone,eye" DRSC29889 K -1.44745241 0.288303436 -0.546391553 -0.127353177 -0.186707552 -1.508210064 FBgn0058178 CG40178 http://flybase.net/reports/FBgn0058178.html FBan0040178 protein_coding_gene 0045454=cell redox homeostasis CG40178/CG41283 "IPR013766=Thioredoxin domain, IPR001623=DnaJ domain, IPR012336=Thioredoxin-like fold, IPR018253=DnaJ domain, conserved site" CG40178 16-Dec-15 2015_12 ENSDARG00000059699(LOC559762) WBGene00001026(dnj-8) ENSXETG00000006830(DNAJC16) ENSMUSG00000040697(Dnajc16) ENSG00000116138(DNAJC16) FBgn0032195 CG4908 http://flybase.net/reports/FBgn0032195.html protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" "0034551=mitochondrial respiratory chain complex III assembly, 0006461=protein complex assembly" 0005743=mitochondrial inner membrane "IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR027243=Mitochondrial chaperone BCS1, IPR014851=BCS1, N-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG4908 16-Dec-15 2015_12 ENSDARG00000012295(bcs1l) YDR375C(BCS1) WBGene00010042(bcs-1) ENSXETG00000013844(bcs1l) ENSMUSG00000026172(Bcs1l) ENSG00000074582(BCS1L) viable FBgn0010238 Lac Lachesin http://flybase.net/reports/FBgn0010238.html FBgn0021933 protein_coding_gene 0042803=protein homodimerization activity "0061343=cell adhesion involved in heart morphogenesis, 0035151=regulation of tube size, open tracheal system, 0016331=morphogenesis of embryonic epithelium, 0019991=septate junction assembly, 0035160=maintenance of epithelial integrity, open tracheal system, 0007424=open tracheal system development, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" "0005918=septate junction, 0005886=plasma membrane, 0019898=extrinsic component of membrane" "l(2)k11012b, lachesin bulbous, CG12369, l(2)k11012, bulbous, CT24921, bulb, lachesin, lac" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain" CG12369 16-Dec-15 2015_12 "ENSDARG00000034273(sid4),ENSDARG00000009866" ENSXETG00000016639(LSAMP) "ENSMUSG00000040037(Negr1),ENSMUSG00000061080(Lsamp)" "ENSG00000172260(NEGR1),ENSG00000185565(LSAMP)" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "presumptive embryonic/larval tracheal system,tracheocyte,dorsal group branch precursor,lateral group branch precursor,presumptive embryonic salivary gland,dorsal trunk primordium,septate junction,PNS glial cell,CNS glial cell,taenidial fold,embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system" FBgn0011708 Syx5 Syntaxin 5 http://flybase.net/reports/FBgn0011708.html "FBgn0001996, FBgn0015339, FBgn0020602" protein_coding_gene "0042803=protein homodimerization activity, 0000149=SNARE binding, 0005484=SNAP receptor activity" "0045930=negative regulation of mitotic cell cycle, 0007030=Golgi organization, 0006909=phagocytosis, 0007112=male meiosis cytokinesis, 0009306=protein secretion, 0000281=mitotic cytokinesis, 0007283=spermatogenesis, 0008283=cell proliferation, 0007269=neurotransmitter secretion, 0016081=synaptic vesicle docking, 0055070=copper ion homeostasis, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0006878=cellular copper ion homeostasis, 0060305=regulation of cell diameter, 0000902=cell morphogenesis, 0006887=exocytosis, 0035167=larval lymph gland hemopoiesis" "0000139=Golgi membrane, 0012505=endomembrane system, 0005801=cis-Golgi network, 0005794=Golgi apparatus, 0005886=plasma membrane, 0031201=SNARE complex, 0005783=endoplasmic reticulum" "Syx5A, syntaxin5, syntaxin 5, lethal(2)35Ff, syntaxin, syn5, SED5, l(2)35Ff, dSyx5, Syntaxin 5, Syntaxin, Synx5, DmSyx5, Sed5, SYN5, anon-35Fd, Syx, sed5, CG4214, dsyntaxin5, syx5, dSyntaxin5, dSed5, anon-35Fb, dSed5p, dsed5, BG:DS02740.12, II" "IPR010989=t-SNARE, IPR006012=Syntaxin/epimorphin, conserved site, IPR000727=Target SNARE coiled-coil homology domain" CG4214 16-Dec-15 2015_12 "ENSDARG00000025033(stx5a),ENSDARG00000003175(stx5al)" YLR026C(SED5) WBGene00006373(syx-5) ENSXETG00000019453(stx5a) ENSMUSG00000010110(Stx5a) ENSG00000162236(STX5) " adult stage , embryonic stage " "lethal,recessive,visible,partially lethal - majority die,cytokinesis defective,male sterile,wild-type,chemical resistant,dominant" "adult cuticle,scutellum,chaeta,spermatozoon,testis,Nebenkern,embryonic/larval salivary gland,Golgi stack,endoplasmic reticulum,thorax" DRSC03432 IEK -0.255476752 2.623973357 1.555155686 -1.557426759 -2.272766512 -1.0368977 FBgn0039066 EloA Elongin A http://flybase.net/reports/FBgn0039066.html protein_coding_gene 0003677=DNA binding "0007474=imaginal disc-derived wing vein specification, 0006368=transcription elongation from RNA polymerase II promoter, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter" "0035327=transcriptionally active chromatin, 0008023=transcription elongation factor complex, 0005634=nucleus, 0070449=elongin complex, 0016021=integral component of membrane" "dEloA, Elongin-A, Elo-A, ElonginA, CG6755" "IPR010684=RNA polymerase II transcription factor SIII, subunit A, IPR017923=Transcription factor IIS, N-terminal" CG6755 16-Dec-15 2015_12 ENSDARG00000011637(zgc:55573) WBGene00010990(R03D7.4) ENSXETG00000021628() ENSMUSG00000028668(Tceb3) "ENSG00000011007(TCEB3),ENSG00000206181(TCEB3B)" "lethal - all die before end of pupal stage,some die during pupal stage,lethal,visible,somatic clone,viable" "wing vein,ectopic,wing margin,somatic clone" DRSC16109 EK 0.626121923 0.755874923 1.59185246 0.976145324 2.299562316 0.745544605 FBgn0037130 Syn1 Syntrophin-like 1 http://flybase.net/reports/FBgn0037130.html FBgn0037132 protein_coding_gene "0008307=structural constituent of muscle, 0008092=cytoskeletal protein binding" "0040011=locomotion, 0008582=regulation of synaptic growth at neuromuscular junction" 0016013=syntrophin complex "CG7152, DmSYN-1, CG7151, Syntrophin" "IPR001478=PDZ domain, IPR031072=Syntrophin-1, IPR015482=Syntrophin, IPR001849=Pleckstrin homology domain" CG7152 16-Dec-15 2015_12 ENSDARG00000041729(zgc:92432) WBGene00006062(stn-1) "ENSXETG00000005757(SNTB1),ENSXETG00000021433(SNTA1)" "ENSMUSG00000060429(Sntb1),ENSMUSG00000041308(Sntb2),ENSMUSG00000027488(Snta1)" "ENSG00000172164(SNTB1),ENSG00000168807(SNTB2),ENSG00000101400(SNTA1)" "partially lethal - majority die,song defective,viable" FBgn0003390 shf shifted http://flybase.net/reports/FBgn0003390.html FBgn0029901 protein_coding_gene 0005515=protein binding "0008589=regulation of smoothened signaling pathway, 0007224=smoothened signaling pathway, 0016055=Wnt signaling pathway, 0050821=protein stabilization, 0008039=synaptic target recognition, 0045880=positive regulation of smoothened signaling pathway" "0005576=extracellular region, 0005578=proteinaceous extracellular matrix" "WNT inhibitory factor, Shf, D-Wif, DmWif, shf-ov, DmWIF, CG3135, Shifted, CG3134, CT10514" "IPR013032=EGF-like, conserved site, IPR013309=Wnt inhibitory factor (WIF)-1, IPR003306=WIF domain, IPR000742=EGF-like domain" CG3135 16-Dec-15 2015_12 ENSDARG00000005541(wif1) WBGene00019901(R05G6.9) ENSXETG00000013842() ENSMUSG00000020218(Wif1) ENSG00000156076(WIF1) "viable,partially lethal - majority die,recessive,female sterile,small body,partially lethal - majority live,sterile,reduced,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile,semi-sterile,visible,poor" "wing,1st posterior cell,wing vein L3,scutellum,eye,scutellar bristle,wing vein L4,metathoracic leg,anterior crossvein,posterior scutellar bristle,denticle belt,wing vein,wing basal cell 1,postvertical bristle,ommatidium" FBgn0000385 ctl coatless http://flybase.net/reports/FBgn0000385.html gene 0001700=embryonic development via the syncytial blastoderm 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030103 Obp8a Odorant-binding protein 8a http://flybase.net/reports/FBgn0030103.html protein_coding_gene 0005549=odorant binding 0007606=sensory perception of chemical stimulus 0005576=extracellular region "DmelObp8a, 8a, CG12665" IPR006170=Pheromone/general odorant binding protein CG12665 16-Dec-15 2015_12 viable FBgn0022361 Pur-ë± Purine-rich binding protein-ë± http://flybase.net/reports/FBgn0022361.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003723=RNA binding, 0003677=DNA binding, 0003697=single-stranded DNA binding, 0003729=mRNA binding" 0031935=regulation of chromatin silencing "1990124=messenger ribonucleoprotein complex, 0005737=cytoplasm, 0005634=nucleus" "CG1507, Pur alpha, Pur-a, Pur-alpha, dPur alpha, PURalpha, pur-alpha" IPR006628=Purine-rich element binding protein family CG1507 16-Dec-15 2015_12 "ENSDARG00000055542,ENSDARG00000024890(LOC557266),ENSDARG00000053022" WBGene00004046(plp-1) "ENSXETG00000003837(PURA),ENSXETG00000001257(PURB),ENSXETG00000018299(PURG)" "ENSMUSG00000043991(Pura),ENSMUSG00000049647(Purb),ENSMUSG00000049184(Purg)" "ENSG00000146676(PURB),ENSG00000185129(PURA)" "lethal,male limited,viable" FBgn0038853 RhoGAP93B Rho GTPase activating protein at 93B http://flybase.net/reports/FBgn0038853.html protein_coding_gene 0005096=GTPase activator activity "0007411=axon guidance, 0043547=positive regulation of GTPase activity, 0016199=axon midline choice point recognition" "0005856=cytoskeleton, 0005737=cytoplasm" "RhoGAP, CrGAP, Vilse, CG3421, vilse, RhoGAP93B" "IPR000198=Rho GTPase-activating protein domain, IPR001202=WW domain, IPR000857=MyTH4 domain, IPR008936=Rho GTPase activation protein" CG3421 16-Dec-15 2015_12 ENSDARG00000044874(zgc:92107) ENSXETG00000007442() ENSMUSG00000033697(Arhgap39) ENSG00000147799(ARHGAP39) "viable,fertile,lethal,recessive,germline clone,visible" "ganglionic branch primordium,longitudinal connective,eye,medial longitudinal fascicle,ventral midline,commissure" FBgn0069113 mus217 mutagen-sensitive 217 http://flybase.net/reports/FBgn0069113.html gene 16-Dec-15 2015_12 "viable,chemical sensitive" FBgn0023542 Nmd3 Nonsense-mediated mRNA 3 http://flybase.net/reports/FBgn0023542.html FBgn0014089 protein_coding_gene 0003729=mRNA binding "0009267=cellular response to starvation, 0000055=ribosomal large subunit export from nucleus, 0022008=neurogenesis" "transcription unit III, TcD13, EG:152A3.1, CG3460, TcD12, anon-2Eb, II, dNmd3" IPR007064=NMD3 CG3460 16-Dec-15 2015_12 ENSDARG00000015676(nmd3) YHR170W(NMD3) WBGene00012030(T25G3.3) ENSXETG00000027727(nmd3) ENSMUSG00000027787(Nmd3) ENSG00000169251(NMD3) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0004648 svr silver http://flybase.net/reports/FBgn0004648.html "FBgn0000268, FBgn0000521, FBgn0003652, FBgn0012063, FBgn0029527, FBgn0052818" protein_coding_gene "0004180=carboxypeptidase activity, 0004185=serine-type carboxypeptidase activity, 0008270=zinc ion binding, 0004181=metallocarboxypeptidase activity" "0006909=phagocytosis, 0007616=long-term memory, 0040003=chitin-based cuticle development, 0006508=proteolysis, 0007476=imaginal disc-derived wing morphogenesis" "0005576=extracellular region, 0012505=endomembrane system, 0048471=perinuclear region of cytoplasm" "CG18503, DmSilver, CypD, carboxypeptidase D, pointed, Carboxypeptidase E, cc, CpepE, chlorotic, CPD, Silver, Carboxypeptidase D, EG:171D11.3, dwp, CG4122, poi, carboxypeptidase, CP, CG32818, EP(X)0356, l(1)1Bd, dwarp, slv" "IPR008969=Carboxypeptidase-like, regulatory domain, IPR015567=Peptidase M14B, caboxypeptidase D, IPR014766=Carboxypeptidase, regulatory domain, IPR000834=Peptidase M14, carboxypeptidase A" CG4122 16-Dec-15 2015_12 ENSMUSG00000020841(Cpd) ENSG00000108582(CPD) embryonic stage "viable,electrophoretic variant,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,poor,body color defective,cold stress response defective,memory defective,fertile,partially lethal - majority die" "wing,wing blade,wing vein,wing vein L3,wing vein L4,wing vein L5,anterior crossvein,posterior crossvein,microchaeta,wing vein L1,wing vein L2" FBgn0044419 Pmi Pmi http://flybase.net/reports/FBgn0044419.html "FBgn0035635, FBgn0052912, FBgn0053718, FBtr0077105, FBpp0076811, FBtr0077106, FBpp0076812, FBtr0077107, FBpp0076813, FBtr0077108, FBpp0076814, FBtr0077109, FBpp0076815" protein_coding_gene "0007005=mitochondrion organization, 0007007=inner mitochondrial membrane organization, 0042775=mitochondrial ATP synthesis coupled electron transport, 0070584=mitochondrion morphogenesis" "0005743=mitochondrial inner membrane, 0031305=integral component of mitochondrial inner membrane" "PMI, CG33718, CG32912, CG5523" IPR026120=Transmembrane protein 11 CG33718 16-Dec-15 2015_12 "ENSDARG00000070861,ENSDARG00000070866(tmem11)" ENSXETG00000006056(TMEM11) ENSMUSG00000043284(Tmem11) ENSG00000178307(TMEM11) FBgn0005418 l(1)adl7 lethal (1) adl7 http://flybase.net/reports/FBgn0005418.html gene l(1)adl-7 16-Dec-15 2015_12 "lethal,female sterile" FBgn0259608 B0799 http://flybase.net/reports/FBgn0259608.html gene 16-Dec-15 2015_12 visible "tarsal segment,proboscis" FBgn0000659 fkh fork head http://flybase.net/reports/FBgn0000659.html FBgn0015292 protein_coding_gene "0043565=sequence-specific DNA binding, 0008301=DNA binding, bending, 0000976=transcription regulatory region sequence-specific DNA binding, 0003690=double-stranded DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0019904=protein domain specific binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding" "0040015=negative regulation of multicellular organism growth, 0042023=DNA endoreduplication, 0043066=negative regulation of apoptotic process, 0035072=ecdysone-mediated induction of salivary gland cell autophagic cell death, 0007435=salivary gland morphogenesis, 0030308=negative regulation of cell growth, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007439=ectodermal digestive tract development, 0007432=salivary gland boundary specification, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0007431=salivary gland development, 0006357=regulation of transcription from RNA polymerase II promoter, 0001706=endoderm formation, 0007443=Malpighian tubule morphogenesis, 0007389=pattern specification process, 0043069=negative regulation of programmed cell death, 0061101=neuroendocrine cell differentiation, 0051090=regulation of sequence-specific DNA binding transcription factor activity" "0005667=transcription factor complex, 0005700=polytene chromosome, 0005634=nucleus" "Sebp2, Fork Head, CG10002, Secretion enhancer-binding protein 2, FKH, Fkh, Fork head, Forkhead, forkhead, dFoxA, Dmfkh, FORK HEAD" "IPR018533=Forkhead box protein, C-terminal, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001766=Fork head domain, IPR018122=Fork head domain conserved site1, IPR013638=Fork-head N-terminal" CG10002 16-Dec-15 2015_12 "ENSDARG00000003411(foxa2),ENSDARG00000019150(foxa1),ENSDARG00000012788(foxa3)" "ENSXETG00000026998(foxa2),ENSXETG00000025867(foxa1),ENSXETG00000026171(TGas072p11.1)" "ENSMUSG00000037025(Foxa2),ENSMUSG00000035451(Foxa1)" "ENSG00000125798(FOXA2),ENSG00000129514(FOXA1)" " embryonic stage | stage 4 , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage 10 , embryonic stage | stage 5 " " organism | 0-20% egg length

,

terminal , hindgut

, Malpighian tubule

,

0-10% egg length , inclusive hindgut primordium

, organism | 90-100% egg length

" " embryonic stage | early , embryonic stage | stage 5 , larval stage | third instar , embryonic stage | stage >11 , embryonic stage | stage 9 " "

posterior , organism | 90-100% egg length

, larval salivary gland

, embryonic central nervous system | presumptive

, organism | 0-20% egg length

, anterior embryonic/larval midgut

, stomodeum

, embryonic/larval salivary gland

, yolk

" "increased cell size,conditional,small body,decreased cell size,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,decreased cell death,lethal,increased cell death,neuroanatomy defective,viable,visible" "cephalopharyngeal skeleton,anal plate,Malpighian tubule primordium,embryonic head,embryo,posterior,embryonic/larval salivary gland,salivary gland,embryonic/larval hindgut,Malpighian tubule,embryonic/larval proventriculus,embryonic/larval esophagus,embryonic brain,embryonic central brain glial cell,embryonic brain & ganglion mother cell,anterior midgut primordium,external sensory organ,ectopic,embryonic/larval foregut,anterior embryonic/larval midgut,labial disc,stomatogastric nervous system,longitudinal visceral muscle primordium,adult salivary gland primordium,embryonic stomatogastric nervous system,embryonic visceral muscle,embryonic hindgut,embryonic central brain,pars intercerebralis,salivary gland common duct primordium,hemocyte,macrophage,visceral mesoderm derivative,somatic mesoderm,mesothoracic tergum" FBgn0051999 CG31999 http://flybase.net/reports/FBgn0051999.html "FBgn0039894, FBgn0039895" protein_coding_gene 0005509=calcium ion binding 0007155=cell adhesion 0005578=proteinaceous extracellular matrix "fibrillin-like, CG11288, CG10323, CT7856, CT31491" "IPR001881=EGF-like calcium-binding domain, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR026823=Complement Clr-like EGF domain, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site" CG31999 16-Dec-15 2015_12 "ENSDARG00000015156(fbln2),ENSDARG00000029738(fbln1)" WBGene00001403(fbl-1) ENSXETG00000000323() ENSMUSG00000064080(Fbln2) ENSG00000163520(FBLN2) "viable,visible" trichogen cell DRSC17131 K -0.240991472 0.105017927 0.23646923 0.429536228 2.231312979 0.904741531 FBgn0010803 Aats-trp Tryptophanyl-tRNA synthetase http://flybase.net/reports/FBgn0010803.html FBgn0037673 protein_coding_gene "0005524=ATP binding, 0004830=tryptophan-tRNA ligase activity" "0048813=dendrite morphogenesis, 0022008=neurogenesis, 0006436=tryptophanyl-tRNA aminoacylation" 0005737=cytoplasm "l(3)03560, CG9735, WRS-85D, tryptophanyl-tRNA synthetase, l(3)03559, l(3)3559, TrpRS, 85D-WRS, wars, WRS" "IPR002305=Aminoacyl-tRNA synthetase, class Ic, IPR002306=Tryptophan-tRNA ligase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site" CG9735 16-Dec-15 2015_12 YOL097C(WRS1) WBGene00006945(wars-1) ENSXETG00000002524(wars) ENSMUSG00000021266(Wars) ENSG00000140105(WARS) " embryonic stage , embryonic stage -- adult stage " embryonic/larval salivary gland

embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,neuroanatomy defective,somatic clone,viable,decreased cell size,cell autonomous" "egg,germline clone,adult antennal lobe projection neuron,somatic clone,gamma Kenyon cell,embryonic/larval neuroblast,ganglion mother cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0086784 stmA stambha A http://flybase.net/reports/FBgn0086784.html "FBgn0003530, FBgn0025937, FBgn0060295" protein_coding_gene "0016079=synaptic vesicle exocytosis, 0048488=synaptic vesicle endocytosis, 0000281=mitotic cytokinesis, 0030100=regulation of endocytosis, 0007268=synaptic transmission, 0007602=phototransduction" "0045202=synapse, 0005886=plasma membrane" "stm-A, CG8739, stambh A, Rolling blackout, rbo, stambhA, cmp44E, rolling blackout, conserved membrane protein at 44E" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG8739 16-Dec-15 2015_12 "ENSDARG00000069318(efr3bb),ENSDARG00000033516(efr3ba),ENSDARG00000069312,ENSDARG00000005163(efr3a)" WBGene00016311(C32D5.3) "ENSXETG00000023031(EFR3A),ENSXETG00000017509(EFR3B)" "ENSMUSG00000020658(Efr3b),ENSMUSG00000015002(Efr3a)" "ENSG00000084710(EFR3B),ENSG00000132294(EFR3A)" " embryonic stage , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage&&adult stage , adult stage && oogenesis stage | stage >=S9 , adult stage && oogenesis stage | stage S1-5 " " embryonic brain

, germarium

, embryonic central nervous system

,

ubiquitous , nurse cell

, follicle cell

" FBgn0030773 CG9676 http://flybase.net/reports/FBgn0030773.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP99 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG9676 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" "viable,visible" trichogen cell FBgn0031732 CG11149 http://flybase.net/reports/FBgn0031732.html protein_coding_gene "0008532=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity" dibeta3GnT4 CG11149 16-Dec-15 2015_12 WBGene00008491(F01D4.9) viable FBgn0028375 heix heixuedian http://flybase.net/reports/FBgn0028375.html FBgn0001993 protein_coding_gene 0004659=prenyltransferase activity "0046578=regulation of Ras protein signal transduction, 0070584=mitochondrion morphogenesis, 0008592=regulation of Toll signaling pathway, 0035204=negative regulation of lamellocyte differentiation, 0035207=negative regulation of hemocyte proliferation, 0035167=larval lymph gland hemopoiesis, 0045610=regulation of hemocyte differentiation, 0009234=menaquinone biosynthetic process, 0043408=regulation of MAPK cascade, 0046425=regulation of JAK-STAT cascade" "0005739=mitochondrion, 0012505=endomembrane system, 0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0016020=membrane" "ipa-6d, 124/1, l(2)35Fc, CG5876, BG:DS02740.7, lethal(2)35Fc, l(2)k12401" "IPR000537=UbiA prenyltransferase family, IPR026046=UbiA prenyltransferase domain containing protein 1" CG5876 16-Dec-15 2015_12 ENSDARG00000013009(LOC558410) ENSXETG00000017414(UBIAD1) ENSMUSG00000047719(Ubiad1) ENSG00000120942(UBIAD1) "lethal,recessive,visible,melanotic mass phenotype,viable" "imaginal disc,wing vein,melanotic mass,hemocyte,wing,trichogen cell,mesothoracic tergum" FBgn0053852 His1:CG33852 His1:CG33852 http://flybase.net/reports/FBgn0053852.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33852 "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5" CG33852 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0033812 Pex13 Peroxin 13 http://flybase.net/reports/FBgn0033812.html protein_coding_gene "0007031=peroxisome organization, 0016560=protein import into peroxisome matrix, docking, 0048137=spermatocyte division" "0005778=peroxisomal membrane, 0005777=peroxisome, 0016021=integral component of membrane" "peroxin 13, pex13, PEX13, CG4663, DmelPex13" "IPR001452=SH3 domain, IPR007223=Peroxin 13, N-terminal" CG4663 16-Dec-15 2015_12 "ENSDARG00000071037(pex13),ENSDARG00000071038" YLR191W(PEX13) WBGene00004198(prx-13) ENSXETG00000002212(pex13) ENSMUSG00000020283(Pex13) ENSG00000162928(PEX13) "viable,cytokinesis defective,meiotic cell cycle defective" "spermatid,testis" FBgn0086693 iav inactive http://flybase.net/reports/FBgn0086693.html "FBgn0029904, FBgn0001246" protein_coding_gene "0005261=cation channel activity, 0005262=calcium channel activity" "0006812=cation transport, 0001964=startle response, 0007605=sensory perception of sound, 0006816=calcium ion transport, 0009408=response to heat, 0043052=thermotaxis, 0055085=transmembrane transport, 0048148=behavioral response to cocaine, 0048060=negative gravitaxis, 0007608=sensory perception of smell, 0010996=response to auditory stimulus, 0007629=flight behavior, 0040040=thermosensory behavior" 0034703=cation channel complex "DmIav, inactive, Inactive, CT14708, IAV, TRPV, osm-9, INACTIVE, hypoB, CG4536, Iav" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR005821=Ion transport domain" CG4536 16-Dec-15 2015_12 "ENSDARG00000014496(trpv6),ENSDARG00000061941(trpv4)" WBGene00003889(osm-9) "ENSXETG00000022857(),ENSXETG00000005790(TRPV1),ENSXETG00000005811(TRPV2),ENSXETG00000018609(),ENSXETG00000003136(),ENSXETG00000005788(TRPV3),ENSXETG00000003140(),ENSXETG00000013395(),ENSXETG00000011201()" "ENSMUSG00000036899(Trpv5),ENSMUSG00000029868(Trpv6)" "ENSG00000127412(TRPV5),ENSG00000165125(TRPV6)" FBgn0261387 CG17528 http://flybase.net/reports/FBgn0261387.html "FBgn0014005, FBgn0032999, FBan0017528, FBgn0058283" protein_coding_gene "0008017=microtubule binding, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0007017=microtubule-based process, 0035556=intracellular signal transduction" 0005875=microtubule associated complex "Protein kinase 1, CAMK-like, PK1, Pk1, CG40283" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR003533=Doublecortin domain" CG17528 16-Dec-15 2015_12 ENSDARG00000034093(dclk2) WBGene00006993(zyg-8) ENSXETG00000018862(DCLK2) "ENSMUSG00000027797(Dclk1),ENSMUSG00000028078(Dclk2)" "ENSG00000133083(DCLK1),ENSG00000170390(DCLK2)" DRSC07761 K 1.452913501 0.131312635 0.282892923 0.325500783 0.500757903 1.656925502 FBgn0033215 CG1942 http://flybase.net/reports/FBgn0033215.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" 0007498=mesoderm development DGAT2 IPR007130=Diacylglycerol acyltransferase CG1942 16-Dec-15 2015_12 "ENSDARG00000019228(mogat2),ENSDARG00000018846(dgat2),ENSDARG00000003635(LOC565116),ENSDARG00000070072" YOR245C(DGA1) "WBGene00019464(K07B1.4),WBGene00021818(Y53G8B.2),WBGene00020910(W01A11.2),WBGene00010296(F59A1.10)" "ENSXETG00000002935(mogat1),ENSXETG00000004012(mogat2),ENSXETG00000015062(),ENSXETG00000023190(),ENSXETG00000025317(dgat2)" "ENSMUSG00000052396(Mogat2),ENSMUSG00000012187(Mogat1),ENSMUSG00000030747(Dgat2),ENSMUSG00000067597(Dgat2l6),ENSMUSG00000031220(Awat2),ENSMUSG00000015665(Awat1)" "ENSG00000166391(MOGAT2),ENSG00000124003(MOGAT1),ENSG00000062282(DGAT2),ENSG00000106384(MOGAT3),ENSG00000204195(AWAT1),ENSG00000184210(DGAT2L6),ENSG00000147160(AWAT2)" "viable,fertile" FBgn0085387 shakB shaking B http://flybase.net/reports/FBgn0085387.html "FBan0032508, FBgn0052508, FBgn0031131, FBgn0003037, FBgn0031133" protein_coding_gene 0005243=gap junction channel activity "0007602=phototransduction, 0010496=intercellular transport, 0003254=regulation of membrane depolarization, 0009416=response to light stimulus, 0016264=gap junction assembly, 0007630=jump response, 0010644=cell communication by electrical coupling" "0005886=plasma membrane, 0005921=gap junction" "nj156, 6, E81, nj-156, shkB, l(1)W3b, 3, shaking-B, l(1)R-10-14, non-jumper-156, l(1)R-10-7, passover, section 6, l(1)LB21, l(1)TH73, CG34358, passover-vital protein, Pas, CG12678, FBpp0111481, 2, lincRNA.1031, CG1321, ShakB, R-9-29, Shaking-B, section 3, shaking B, Passover, pas, l(1)19Eb, l(1)R-10-3, pass, section 2, Shak-B, inx8, shB, CG15451, Shak B, R9-29, l(1)R-9-29, CG32508, shak-B, W3, Shaking B, l(1)W3" IPR000990=Innexin CG34358 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" " adult stage , pupal stage | >75hr " " mesothoracic neuromere

, giant fibers

" FBgn0029174 FKBP59 FK506-binding protein FKBP59 http://flybase.net/reports/FBgn0029174.html "FBgn0015990, FBgn0022021, FBgn0032152, FBgn0062203" protein_coding_gene "0005515=protein binding, 0003755=peptidyl-prolyl cis-trans isomerase activity, 0005528=FK506 binding" "0051924=regulation of calcium ion transport, 0050908=detection of light stimulus involved in visual perception, 0006457=protein folding, 0018208=peptidyl-proline modification, 0007422=peripheral nervous system development" 0016027=inaD signaling complex "FKBP59-bp1, CG4535, l(2)k09010, anon-WO0118547.161, dFKBP59, l(2)k00424" "IPR013026=Tetratricopeptide repeat-containing domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR011990=Tetratricopeptide-like helical domain, IPR019734=Tetratricopeptide repeat, IPR001440=Tetratricopeptide repeat 1" CG4535 16-Dec-15 2015_12 "ENSDARG00000008447(fkbp4),ENSDARG00000028396(fkbp5)" WBGene00001431(fkb-6) ENSXETG00000001644(FKBP4) "ENSMUSG00000030357(Fkbp4),ENSMUSG00000024222(Fkbp5)" "ENSG00000004478(FKBP4),ENSG00000096060(FKBP5)" " embryonic stage | stage >=13 , embryonic stage -- adult stage , embryonic stage | stage >=16 " " embryonic/larval garland cell

, embryonic/larval oenocyte

, lymph gland

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,partially lethal - majority die" "crystal cell,plasmatocyte,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,fascicle" FBgn0004360 Wnt2 Wnt oncogene analog 2 http://flybase.net/reports/FBgn0004360.html protein_coding_gene "0005109=frizzled binding, 0005102=receptor binding" "0009952=anterior/posterior pattern specification, 0016055=Wnt signaling pathway, 0009798=axis specification, 0007517=muscle organ development, 0060070=canonical Wnt signaling pathway, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007424=open tracheal system development, 0048675=axon extension" "0005615=extracellular space, 0005886=plasma membrane, 0005576=extracellular region" "DWnt2, wnt2, dWnt2, Wnt-2, Dm DWnt2, D-wnt-2, Dwnt-2, Wnt, Dm-2, CG1916, DWnt-2" "IPR005817=Wnt, IPR018161=Wnt protein, conserved site" CG1916 16-Dec-15 2015_12 "ENSDARG00000071107,ENSDARG00000022858,ENSDARG00000044827(wnt7a),ENSDARG00000002483" WBGene00000858(cwn-2) ENSXETG00000003073(WNT7B) "ENSMUSG00000022382(Wnt7b),ENSMUSG00000030093(Wnt7a)" "ENSG00000188064(WNT7B),ENSG00000154764(WNT7A)" " embryonic stage | stage 5 , embryonic stage | stage 10-11 , pupal stage | 24 hr , embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage | stage >=13 , wandering third instar larval stage , embryonic stage | stage 7 , embryonic stage | stage 15 , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 13 , embryonic stage--pupal stage " " organism | 10-70% egg length

, thoracic segment &&of embryo

, seminal vesicle | restricted

, gonad | posterior

, abdominal segment 1--8 | restricted

, organism | anterior

, male genital disc primordium

, proctodeum

, gonad

, labial segment

, maxillary segment

, labrum

, organism | posterior

" "male sterile,recessive,viable,visible,flightless,heat sensitive,reduced,neuroanatomy defective,dominant,male semi-sterile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "testis pigment cell,testis sheath muscle,wing,testis sheath,testis,muscle of third axillary 54,heat sensitive,basalar muscle 52,direct flight muscle,axon & dorsal cluster neuron,ectopic,ovary,somatic clone,direct flight muscle 49,direct flight muscle 50,muscle of first axillary 53,dorsal trunk primordium,embryonic/larval tracheal system" FBgn0000115 Arl1 ADP ribosylation factor-like 1 http://flybase.net/reports/FBgn0000115.html "FBgn0016902, FBgn0064936" protein_coding_gene "0005515=protein binding, 0003924=GTPase activity, 0005525=GTP binding, 0019904=protein domain specific binding" "0033363=secretory granule organization, 0016197=endosomal transport, 0000042=protein targeting to Golgi, 0007431=salivary gland development, 0035220=wing disc development, 0033227=dsRNA transport, 0090158=endoplasmic reticulum membrane organization, 0070861=regulation of protein exit from endoplasmic reticulum, 0034067=protein localization to Golgi apparatus, 0007269=neurotransmitter secretion, 0060628=regulation of ER to Golgi vesicle-mediated transport, 0006471=protein ADP-ribosylation, 0030334=regulation of cell migration, 0048488=synaptic vesicle endocytosis, 0007264=small GTPase mediated signal transduction, 0007030=Golgi organization" "0005802=trans-Golgi network, 0005794=Golgi apparatus" "Arl1, Arflike at 72A, ARL1, l(3)72Ae, arl, P25160, 72CDd, arf72A, arl1, Arf72A, dArl1, unnamed, CG6025, Arf, CG 6025, BcDNA:GM20805, arf[72A], l(3)72CDd, ARL1_DROME, dARL1p, Arf-like 1" "IPR006689=Small GTPase superfamily, ARF/SAR type, IPR005225=Small GTP-binding protein domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR024156=Small GTPase superfamily, ARF type" CG6025 16-Dec-15 2015_12 ENSDARG00000014310 YBR164C(ARL1) WBGene00000187(arl-1) ENSXETG00000002540(arl1) ENSMUSG00000060904(Arl1) ENSG00000120805(ARL1) "lethal,recessive,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type" "syncytial blastoderm embryo,centrosome | embryonic stage 4,nucleus | embryonic stage 4,spindle,centrosome,nucleus,rough endoplasmic reticulum membrane | somatic clone,Golgi apparatus | somatic clone | supernumerary" DRSC09667 I 2.519406708 1.030597829 0.484817192 0.135591051 -0.42210832 0.307748674 FBgn0041761 dra drache http://flybase.net/reports/FBgn0041761.html gene 16-Dec-15 2015_12 "melanotic mass phenotype,recessive,lethal,hyperplasia" "polytene chromosome,melanotic mass,embryonic/larval brain" FBgn0005654 lat latheo http://flybase.net/reports/FBgn0005654.html "FBgn0002075, FBgn0004955, FBgn0023182" protein_coding_gene 0003677=DNA binding "0051297=centrosome organization, 0007612=learning, 0030536=larval feeding behavior, 0008355=olfactory learning, 0006260=DNA replication, 0051298=centrosome duplication, 0007611=learning or memory, 0007298=border follicle cell migration, 0006270=DNA replication initiation" "0005664=nuclear origin of replication recognition complex, 0072686=mitotic spindle" "LAT, DmORC3, ORC, vr-6, vr6, DmOrc3, Orc3, CG4088, l(2)49Fd, ORC3, l(2)vr6, orc3, Origin recognition complex subunit 3" "IPR020795=Origin recognition complex, subunit 3" CG4088 16-Dec-15 2015_12 ENSDARG00000008805(orc3l) ENSXETG00000019801(ORC3L) ENSMUSG00000040044(Orc3l) ENSG00000135336(ORC3) " adult stage , embryonic stage&&larval stage " adult brain

" larval stage | third instar , adult stage " " bouton

, neuromuscular junction

, adult brain

" "lethal,memory defective,learning defective,recessive,viable,neurophysiology defective,neuroanatomy defective,locomotor behavior defective,behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,non-suppressor of variegation,dominant,suppressor of variegation,wild-type" "border follicle cell,somatic clone,adult mushroom body,axon terminus,bouton,imaginal disc,embryonic/larval central nervous system" FBgn0004849 Su(var)2-1 Suppressor of variegation 2-1 http://flybase.net/reports/FBgn0004849.html "FBgn0003586, FBgn0003589, FBgn0003606, FBgn0003609, FBgn0003611, FBgn0003615, FBgn0003616, FBgn0003617" gene "Su-var(2)1, Su(var), unnamed, Suvar(2)1, Su(Var)2-1, Su(var)2, Su(var)216, Su(var)b[101], Su(var)2-101, Su(var)210, Suvar(2)1[o1]" 16-Dec-15 2015_12 "suppressor of variegation,dominant,lethal,male,recessive,female,partially,viable,non-suppressor of variegation,fertile,female sterile" pigment cell FBgn0025680 cry cryptochrome http://flybase.net/reports/FBgn0025680.html "FBgn0044674, FBgn0044686, FBgn0044708, FBgn0046448" protein_coding_gene "0009881=photoreceptor activity, 0003913=DNA photolyase activity, 0009882=blue light photoreceptor activity, 0008020=G-protein coupled photoreceptor activity, 0071949=FAD binding, 0050660=flavin adenine dinucleotide binding, 0005515=protein binding" "0071000=response to magnetism, 0009637=response to blue light, 0009588=UV-A, blue light phototransduction, 0045187=regulation of circadian sleep/wake cycle, sleep, 0045475=locomotor rhythm, 0007623=circadian rhythm, 0009785=blue light signaling pathway, 0009649=entrainment of circadian clock, 0009416=response to light stimulus, 0000060=protein import into nucleus, translocation, 0045892=negative regulation of transcription, DNA-templated, 0050980=detection of light stimulus involved in magnetoreception, 0050958=magnetoreception, 0006281=DNA repair, 0043153=entrainment of circadian clock by photoperiod, 0042752=regulation of circadian rhythm, 0007602=phototransduction, 0042332=gravitaxis" "0005634=nucleus, 0043234=protein complex, 0005641=nuclear envelope lumen, 0005737=cytoplasm" "Dmcry, anon-WO0140519.20, DmCRY, cryptochrome, cryb, DCry, dCRY, CRY, Cry, CG3772, Blue-light receptor, dcry, anon-WO0140519.19, Dm-CRY1, crybaby, CRYPTOCHROME, dCry, Cryptochrome, anon-WO0140519.17, anon-WO0172774.15, DmCRY1" "IPR002081=Cryptochrome/DNA photolyase, class 1, IPR006050=DNA photolyase, N-terminal, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR005101=Cryptochrome/photolyase FAD-binding domain" CG3772 16-Dec-15 2015_12 YOR386W(PHR1) " adult stage , larval stage , pupal stage " " mouthpart

, leg

, pupal/adult digestive system | restricted

, neuron | subset

, adult head

, antenna

, adult central nervous system

, adult brain

" adult stage adult head

"locomotor rhythm defective,circadian behavior defective,viable,fertile,circadian rhythm defective,recessive,photoperiod response variant,gravitaxis defective,eclosion rhythm defective,behavior defective" "antenna,pacemaker neuron" DRSC16928 E 0.449375925 0.285041601 2.790656486 -0.035784889 -0.22056617 -0.384923258 FBgn0003994 vtw vertical wings http://flybase.net/reports/FBgn0003994.html gene "0007517=muscle organ development, 0014706=striated muscle tissue development" vertical wing 16-Dec-15 2015_12 "flightless,viable,recessive,locomotor behavior defective,visible,reduced" "wing,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,myofibril,Z disc,tergosternal muscle 47a,tergosternal muscle 47b,tergosternal muscle 47c,dorsal medial muscle 45c,dorsal medial muscle 45d,dorsal medial muscle 45e,dorsal medial muscle 45f,coxal tergal remotor muscle 48a,coxal tergal remotor muscle 48b,lateral oblique dorsal muscle 46a,lateral oblique dorsal muscle 46b,thorax,adult thorax" FBgn0038984 AdipoR Adiponectin receptor http://flybase.net/reports/FBgn0038984.html protein_coding_gene "0042562=hormone binding, 0097003=adipokinetic hormone receptor activity" "0019395=fatty acid oxidation, 0009755=hormone-mediated signaling pathway, 0042593=glucose homeostasis, 0032024=positive regulation of insulin secretion, 0070328=triglyceride homeostasis, 0033211=adiponectin-activated signaling pathway, 0036099=female germ-line stem cell maintenance" 0016021=integral component of membrane "adiponectin receptor, CG5315, dAdipoR" IPR004254=AdipoR/Haemolysin-III-related CG5315 16-Dec-15 2015_12 "ENSDARG00000002912(adipor1a),ENSDARG00000042717(adipor1b),ENSDARG00000058688(adipor2)" "YOL002C(IZH2),YDR492W(IZH1)" "WBGene00016610(paqr-1),WBGene00021313(paqr-2)" "ENSXETG00000009404(ADIPOR2),ENSXETG00000007972(Q66KJ1_XENTR)" "ENSMUSG00000026457(Adipor1),ENSMUSG00000030168(Adipor2)" "ENSG00000006831(ADIPOR2),ENSG00000159346(ADIPOR1)" "lethal - all die before end of pupal stage,some die during pupal stage,starvation stress response defective" FBgn0027583 CG7601 http://flybase.net/reports/FBgn0027583.html protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process BcDNA:GH06026 "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase, IPR020904=Short-chain dehydrogenase/reductase, conserved site" CG7601 16-Dec-15 2015_12 "ENSDARG00000057753,ENSDARG00000057807" YMR226C() "WBGene00000993(dhs-30),WBGene00020810(T25G12.2)" ENSXETG00000006052(DHRS7B) ENSMUSG00000042569(Dhrs7b) ENSG00000109016(DHRS7B) viable FBgn0026319 Traf4 TNF-receptor-associated factor 4 http://flybase.net/reports/FBgn0026319.html protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" "0001654=eye development, 0034332=adherens junction organization, 0007391=dorsal closure, 0007165=signal transduction, 0043065=positive regulation of apoptotic process, 0045167=asymmetric protein localization involved in cell fate determination, 0035071=salivary gland cell autophagic cell death, 0006952=defense response, 0016567=protein ubiquitination, 0046529=imaginal disc fusion, thorax closure, 0046330=positive regulation of JNK cascade, 0003384=apical constriction involved in gastrulation, 0048102=autophagic cell death, 0007370=ventral furrow formation, 0006909=phagocytosis, 0007250=activation of NF-kappaB-inducing kinase activity, 0050829=defense response to Gram-negative bacterium" "0005737=cytoplasm, 0045179=apical cortex, 0045177=apical part of cell" "dTRAF, DTRAF1, traf1, TNF Receptor Associated Factor 1, dTraf4, traf4, TNF-receptor-associated factor 1, traf-4, Traf1, TRAF1, CG3048, dTraf1, TRAF4, dtraf1, DTRAF, dTRAF1, TRAF" "IPR013323=SIAH-type domain, IPR002083=MATH/TRAF domain, IPR001293=Zinc finger, TRAF-type, IPR012227=TNF receptor-associated factor TRAF, IPR027138=TNF receptor-associated factor 4, IPR008974=TRAF-like" CG3048 16-Dec-15 2015_12 "ENSDARG00000003963(traf4a),ENSDARG00000038964(traf4b)" WBGene00006612(trf-1) ENSXETG00000027014(traf4) ENSMUSG00000017386(Traf4) ENSG00000076604(TRAF4) "lethal,size defective,lethal - all die before end of larval stage,some die during larval stage,increased cell death,viable,visible,immune response defective,lethal - all die before end of pupal stage,some die during pupal stage" "ventral furrow,embryonic/first instar larval cuticle,rescuable maternal effect,imaginal disc,eye disc,eye photoreceptor cell & axon,eye,ommatidium,eye photoreceptor cell,embryonic/larval salivary gland" FBgn0039136 CG5902 http://flybase.net/reports/FBgn0039136.html FBgn0062061 protein_coding_gene anon-WO0118547.372 "IPR027485=AMMECR1, N-terminal, IPR002733=AMMECR1 domain, IPR023473=AMMECR1" CG5902 16-Dec-15 2015_12 ENSDARG00000012892(zgc:66100) YOR289W() WBGene00011303(R166.3) "ENSXETG00000002956(AMMECR1L),ENSXETG00000024411(AMMECR1)" "ENSMUSG00000042225(Ammecr1),ENSMUSG00000041915(Ammecr1l)" "ENSG00000101935(AMMECR1),ENSG00000144233(AMMECR1L)" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0031799 Pez Pez http://flybase.net/reports/FBgn0031799.html protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0008092=cytoskeletal protein binding" "0035331=negative regulation of hippo signaling, 2000647=negative regulation of stem cell proliferation, 0006470=protein dephosphorylation" "0045177=apical part of cell, 0005938=cell cortex, 0005856=cytoskeleton" "CG9493, PTPD1, dPez" "IPR016130=Protein-tyrosine phosphatase, active site, IPR000299=FERM domain, IPR014352=FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749=Band 4.1 domain, IPR000242=PTP type protein phosphatase, IPR000387=Tyrosine specific protein phosphatases domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR019748=FERM central domain, IPR018980=FERM, C-terminal PH-like domain, IPR018979=FERM, N-terminal, IPR029021=Protein-tyrosine phosphatase-like, IPR029071=Ubiquitin-related domain" CG9493 16-Dec-15 2015_12 ENSDARG00000062248(ptpn21) YOR208W(PTP2) ENSXETG00000023157(PTPN14) "ENSMUSG00000021009(Ptpn21),ENSMUSG00000026604(Ptpn14)" "ENSG00000070778(PTPN21),ENSG00000152104(PTPN14)" "viable,small body,developmental rate defective,semi-sterile,hyperplasia,visible,lethal - all die before end of pupal stage,some die during pupal stage" "adult midgut epithelium,eye,wing" FBgn0043456 CG4747 http://flybase.net/reports/FBgn0043456.html "FBgn0026572, FBgn0032174, FBgn0041705" protein_coding_gene "0008442=3-hydroxyisobutyrate dehydrogenase activity, 0004616=phosphogluconate dehydrogenase (decarboxylating) activity, 0051287=NAD binding" 0055114=oxidation-reduction process 0005705=polytene chromosome interband "Dm_AI388468, BEST:LD22483, LD29743, BEST:LD29743, BEST:GH19401" "IPR029154=3-hydroxyisobutyrate dehydrogenase, NAD-binding domain, IPR016040=NAD(P)-binding domain, IPR000313=PWWP domain, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR006115=6-phosphogluconate dehydrogenase, NADP-binding, IPR013328=6-phosphogluconate dehydrogenase, domain 2" CG4747 16-Dec-15 2015_12 ENSDARG00000037897(glyr1) ENSXETG00000009139(n-pac) ENSMUSG00000022536(Glyr1) ENSG00000140632(GLYR1) visible "dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell" FBgn0035661 CG10477 http://flybase.net/reports/FBgn0035661.html FBgn0044638 protein_coding_gene "0004175=endopeptidase activity, 0004252=serine-type endopeptidase activity" 0006508=proteolysis "NF-YB-like, SP51, anon-WO0140519.232" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG10477 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable DRSC23989 K 0.299582339 -0.620406076 0.502234822 0.36693577 1.930415445 -0.659129085 FBgn0262124 uex unextended http://flybase.net/reports/FBgn0262124.html "FBgn0003946, FBgn0260994, FBan0040084, FBgn0058084, FBan0041594, FBgn0085809, FBgn0022281" protein_coding_gene 0006873=cellular ion homeostasis "EMS45-73, l(2)41Ad, CG40084, l(2Rh)IR3, l(2R)EMS45-73, IR3, 41Ad, l(2R)A', l(2)IR3, CG42595, l(2)EMS34-7, lethal (2) IR3, CR41594, GroupIII" "IPR018490=Cyclic nucleotide-binding-like, IPR002550=Domain of unknown function DUF21, IPR000644=CBS domain, IPR014710=RmlC-like jelly roll fold, IPR000595=Cyclic nucleotide-binding domain" CG42595 16-Dec-15 2015_12 ENSDARG00000061195(cnnm2a) YOL060C(MAM3) "ENSXETG00000018427(CNNM1),ENSXETG00000001249(CNNM4),ENSXETG00000009465(CNNM3),ENSXETG00000009464()" "ENSMUSG00000064105(Cnnm2),ENSMUSG00000037408(Cnnm4)" "ENSG00000148842(CNNM2),ENSG00000158158(CNNM4),ENSG00000119946(CNNM1)" DRSC20784 E 0.324145589 -0.47199125 1.019273922 -2.698217311 0.095512157 0.056224184 FBgn0039856 CG1774 http://flybase.net/reports/FBgn0039856.html protein_coding_gene IPR029069=HotDog domain CG1774 16-Dec-15 2015_12 "ENSDARG00000058352(acot9),ENSDARG00000058390(zgc:123262)" "WBGene00019015(F57F4.1),WBGene00020311(T07D3.9)" ENSXETG00000006223(ACOT9) "ENSMUSG00000025287(Acot9),ENSMUSG00000047565(Acot10)" ENSG00000123130(ACOT9) viable FBgn0015571 ë±-Est3 ë±-Esterase-3 http://flybase.net/reports/FBgn0015571.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "alpha-Ests, B, aE3, alpha-Est3, alphaE3, unnamed, fragment B, CG1257, DmalphaE3" "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold" CG1257 16-Dec-15 2015_12 "WBGene00017205(F07C4.12),WBGene00019654(K11G9.3),WBGene00017431(F13H6.3),WBGene00019653(K11G9.2),WBGene00016862(C52A10.1),WBGene00018958(F56C11.6),WBGene00015071(B0238.7),WBGene00017432(F13H6.4),WBGene00017478(F15A8.6),WBGene00022178(Y71H2AM.13)" "viable,fertile" FBgn0034585 Rbpn-5 Rabaptin-5 http://flybase.net/reports/FBgn0034585.html protein_coding_gene "0017137=Rab GTPase binding, 0008270=zinc ion binding" 0051036=regulation of endosome size "0005737=cytoplasm, 0005769=early endosome" "Rabaptin5, CG4030" "IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR015390=Rabaptin, GTPase-Rab5 binding domain, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR000306=FYVE zinc finger" CG4030 16-Dec-15 2015_12 ENSDARG00000059600(rabep1) YGL023C(PIB2) WBGene00017161(rabn-5) ENSXETG00000021356(rabep1) ENSMUSG00000020817(Rabep1) ENSG00000029725(RABEP1) "visible,planar polarity defective,viable,lethal - all die before end of P-stage,developmental rate defective,neoplasia" "early endosomeptc-559.1,wing vein,wing hair,notal microchaeta,trichome,trichogen cell,wing disc | larval stage" FBgn0250842 CG17575 http://flybase.net/reports/FBgn0250842.html "FBgn0033776, FBgn0066885" protein_coding_gene "0032504=multicellular organism reproduction, 0008104=protein localization, 0046008=regulation of female receptivity, post-mating, 0046692=sperm competition" "0005615=extracellular space, 0005576=extracellular region" anon-SAGE:Wang-113 "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG17575 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" FBgn0043575 PGRP-SC2 PGRP-SC2 http://flybase.net/reports/FBgn0043575.html FBgn0033328 protein_coding_gene "0008270=zinc ion binding, 0042834=peptidoglycan binding, 0008745=N-acetylmuramoyl-L-alanine amidase activity" "0045824=negative regulation of innate immune response, 0009253=peptidoglycan catabolic process, 0006952=defense response, 0006955=immune response" "0005576=extracellular region, 0005887=integral component of plasma membrane" "PGRP-SC, PCRP-SC2, CG14745, Peptidoglycan-recognition protein-SC2 precursor, CG14745 PGRP, Peptidoglycan recognition protein SC2" "IPR002502=N-acetylmuramoyl-L-alanine amidase domain, IPR015510=Peptidoglycan recognition protein, IPR017331=Peptidoglycan recognition protein, PGRP-S, IPR006619=Peptidoglycan recognition protein family domain, metazoa/bacteria" CG14745 16-Dec-15 2015_12 "ENSDARG00000023215,ENSDARG00000068382(pglyrp5)" "ENSXETG00000018262(BC089715.1),ENSXETG00000019028(BC091103.1)" ENSMUSG00000030413(Pglyrp1) ENSG00000008438(PGLYRP1) "long lived,RU486 conditional,viable" "intestinal stem cell,RU486 conditional" FBgn0035421 CG12034 http://flybase.net/reports/FBgn0035421.html protein_coding_gene 0004767=sphingomyelin phosphodiesterase activity 0006684=sphingomyelin metabolic process nSMase IPR005135=Endonuclease/exonuclease/phosphatase CG12034 16-Dec-15 2015_12 "ENSDARG00000052701(LOC797914),ENSDARG00000040523" YER019W(ISC1) WBGene00012105(T27F6.6) ENSXETG00000000421(SMPD2) ENSMUSG00000019822(Smpd2) ENSG00000135587(SMPD2) FBgn0085420 DIP-ë« Dpr-interacting protein ë« http://flybase.net/reports/FBgn0085420.html "FBgn0035606, FBgn0035605" protein_coding_gene "CT15465, CG34391, CG4814, CT35147, DIP-delta, 34391, CG15214" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold" CG34391 16-Dec-15 2015_12 "ENSDARG00000013005(zgc:92901),ENSDARG00000022176(zgc:110372),ENSDARG00000018065(ntm),ENSDARG00000021607(negr1)" WBGene00004372(rig-5) "ENSXETG00000022219(IGLON5),ENSXETG00000015706(OPCML),ENSXETG00000024105(NEGR1)" "ENSMUSG00000059974(Ntm),ENSMUSG00000062257(Opcml),ENSMUSG00000013367(Iglon5)" "ENSG00000182667(NTM),ENSG00000142549(IGLON5),ENSG00000183715(OPCML)" viable DRSC29675 K -0.990768174 0.592195051 0.027897885 1.177903176 1.637429362 -0.953382359 FBgn0003189 r rudimentary http://flybase.net/reports/FBgn0003189.html "FBgn0003548, FBgn0026833, FBgn0042228" protein_coding_gene "0004151=dihydroorotase activity, 0004088=carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, 0070406=glutamine binding, 0004070=aspartate carbamoyltransferase activity, 0005524=ATP binding, 0046872=metal ion binding, 0004087=carbamoyl-phosphate synthase (ammonia) activity, 0016597=amino acid binding" "0006541=glutamine metabolic process, 0006207='de novo' pyrimidine nucleobase biosynthetic process" 0005737=cytoplasm "carbamoylphosphate synthetase, fs(1)M34, CG4601, CPS, CG18572, Rudimentary, ACT, Su(b), fs(1)829, csp2, Suppressor-of-black, DRORUD, GAT, DHO, l(1)Ab, rudimentary gene, CAD, Suppressor of black, PYR1" "IPR013816=ATP-grasp fold, subdomain 2, IPR002082=Aspartate carbamoyltransferase, IPR006680=Amidohydrolase-related, IPR011761=ATP-grasp fold, IPR011607=Methylglyoxal synthase-like domain, IPR005480=Carbamoyl-phosphate synthetase, large subunit oligomerisation domain, IPR016185=Pre-ATP-grasp domain, IPR005483=Carbamoyl-phosphate synthase large subunit, CPSase domain, IPR006275=Carbamoyl-phosphate synthase, large subunit, IPR017926=Glutamine amidotransferase, IPR013815=ATP-grasp fold, subdomain 1, IPR006132=Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding, IPR006130=Aspartate/ornithine carbamoyltransferase, IPR002474=Carbamoyl-phosphate synthase, small subunit N-terminal domain, IPR002195=Dihydroorotase, conserved site, IPR005479=Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR011059=Metal-dependent hydrolase, composite domain, IPR006274=Carbamoyl-phosphate synthase, small subunit, IPR029062=Class I glutamine amidotransferase-like, IPR006131=Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain" CG18572 16-Dec-15 2015_12 ENSDARG00000041895(cad) YJL130C(URA2) WBGene00004259(pyr-1) ENSXETG00000016401(CAD) ENSMUSG00000013629(Cad) ENSG00000084774(CAD) "visible,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,auxotroph,female fertile,wild-type,lethal,rescuable maternal effect,male fertile,viable,reduced,chemical sensitive,cold sensitive,partially lethal - majority die,conditional,poor,chemical resistant" "wing,posterior wing margin,wing margin bristle,rescuable maternal effect,egg,maternal effect,ovary,wing vein,wing vein L4" DRSC19814 I 2.0685602 0.028824778 0.887028118 -0.133973838 -0.286792775 0.378759217 FBgn0022764 Sin3A Sin3A http://flybase.net/reports/FBgn0022764.html "FBgn0010646, FBgn0015704, FBgn0020289, FBgn0024589, FBgn0024647" protein_coding_gene "0003682=chromatin binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003712=transcription cofactor activity, 0046982=protein heterodimerization activity" "0007346=regulation of mitotic cell cycle, 0007526=larval somatic muscle development, 0030178=negative regulation of Wnt signaling pathway, 0008340=determination of adult lifespan, 0035206=regulation of hemocyte proliferation, 0010633=negative regulation of epithelial cell migration, 0007422=peripheral nervous system development, 0006355=regulation of transcription, DNA-templated, 0035220=wing disc development, 0007517=muscle organ development, 0010631=epithelial cell migration, 0045892=negative regulation of transcription, DNA-templated, 0048813=dendrite morphogenesis, 0048666=neuron development, 0031647=regulation of protein stability" "0000785=chromatin, 0016580=Sin3 complex, 0000791=euchromatin, 0017053=transcriptional repressor complex, 0005700=polytene chromosome, 0070822=Sin3-type complex, 0005634=nucleus" "SIN3A, EY2-9, Enhancer of GMR-sina 2-3, dSin3, Sin 3A, Sin3, l(2)k02703, dSin3A, sin3a, l(2)08269, sin3, 27/3, ESTS:159A11T, 159A11T, sin3A, ld, SIN3, 97/15, ES2-3, l(2)k05415, Sin3a, CG8815, sni3, l(2)k09715" "IPR013194=Histone deacetylase interacting, IPR003822=Paired amphipathic helix" CG8815 16-Dec-15 2015_12 "ENSDARG00000062472(sin3b),ENSDARG00000059812(wu:fb95g11)" WBGene00004117(sin-3) ENSXETG00000015283(SIN3A) "ENSMUSG00000031622(Sin3b),ENSMUSG00000042557(Sin3a)" "ENSG00000127511(SIN3B),ENSG00000169375(SIN3A)" embryonic stage

ubiquitous "visible,lethal,recessive,chemical resistant,long lived,chemical conditional,locomotor behavior defective,developmental rate defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,wild-type,partially lethal - majority die,some die during pupal stage,lethal - all die before end of larval stage,heat sensitive,some die during larval stage,hypoplasia,somatic clone,cell migration defective" "wing blade,crystal cell,mitochondrion, with Sin3Aa.cPa,heart primordium,mitochondrion, with Sin3AcPa,eye,somatic clone,photoreceptor cell,pigment cell,trichogen cell,mesothoracic tergum,wing disc,wing vein,wing vein L5" DRSC07552 IEK -1.288607575 2.650463385 -1.85481116 0.784141084 0.755577454 1.831601205 FBgn0028968 ë_COP Coat Protein (coatomer) ë_ http://flybase.net/reports/FBgn0028968.html "FBgn0041590, FBgn0062085" protein_coding_gene 0005198=structural molecule activity "0048812=neuron projection morphogenesis, 0006909=phagocytosis, 0007112=male meiosis cytokinesis, 0007436=larval salivary gland morphogenesis, 0035149=lumen formation, open tracheal system, 0010883=regulation of lipid storage, 0006890=retrograde vesicle-mediated transport, Golgi to ER, 0000281=mitotic cytokinesis, 0009306=protein secretion, 0007424=open tracheal system development, 0008362=chitin-based embryonic cuticle biosynthetic process, 0030198=extracellular matrix organization, 0035158=regulation of tube diameter, open tracheal system, 0006886=intracellular protein transport, 0035147=branch fusion, open tracheal system" "0030126=COPI vesicle coat, 0005801=cis-Golgi network, 0005783=endoplasmic reticulum, 0005794=Golgi apparatus" "gammaCop, l(3)S057302, gammaCOP, COPIgamma, gamma-COP, 0573/02, l(3)S057302b, lethal (3) S057302b, 573.02, anon-WO0118547.334, COPI gamma subunit, gamma-coatomer protein, CG1528, copg" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR017106=Coatomer gamma subunit, IPR009028=Coatomer/calthrin adaptor appendage, C-terminal subdomain, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR013041=Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR013040=Coatomer, gamma subunit, appendage, Ig-like subdomain, IPR015873=Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain" CG1528 16-Dec-15 2015_12 ENSDARG00000034823(si:dkey-117n7.5) YNL287W(SEC21) WBGene00011775(T14G10.5) "ENSXETG00000016290(Q66JI9_XENTR),ENSXETG00000016180(copg)" "ENSMUSG00000030058(Copg),ENSMUSG00000025607(Copg2)" ENSG00000181789(COPG) "lethal - all die before end of embryonic stage,recessive,lethal,some die during embryonic stage,viable,fertile,small body,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval salivary gland,endoplasmic reticulum,embryonic/first instar larval cuticle,denticle belt,embryonic/larval dorsal branch,presumptive embryonic/larval nervous system,onion stage spermatid" DRSC16955 E 0.258494585 -0.145864736 2.646508233 -3.808535445 -1.015292077 -1.269648134 FBgn0041138 l(2)44Dd lethal (2) 44Dd http://flybase.net/reports/FBgn0041138.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036801 MYPT-75D MYPT-75D http://flybase.net/reports/FBgn0036801.html protein_coding_gene "0008157=protein phosphatase 1 binding, 0017020=myosin phosphatase regulator activity" 0007476=imaginal disc-derived wing morphogenesis "CG6896, MYPT75D" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG6896 16-Dec-15 2015_12 "ENSDARG00000069250(LOC565006),ENSDARG00000060238" WBGene00001582(gfi-2) "ENSXETG00000012142(PPP1R16B),ENSXETG00000011619(PPP1R16A)" "ENSMUSG00000037754(Ppp1r16b),ENSMUSG00000033819(Ppp1r16a)" "ENSG00000160972(PPP1R16A),ENSG00000101445(PPP1R16B)" "visible,cell polarity defective,somatic clone,lethal" "wing,oocyte,somatic clone" FBgn0010768 sqz squeeze http://flybase.net/reports/FBgn0010768.html FBgn0061743 protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0048666=neuron development, 0014019=neuroblast development, 0048813=dendrite morphogenesis, 0048477=oogenesis, 0070983=dendrite guidance, 0007517=muscle organ development" 0005634=nucleus "squeeze, l(3)02102, anon-WO0118547.697, CG5557, Squeeze, Sqz, SQZ" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG5557 16-Dec-15 2015_12 ENSXETG00000017550(TEgg083i13.1) "lethal,locomotor behavior defective,partially,recessive,female sterile,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,viable,wild-type,somatic clone" "wing,embryonic/larval neuron,ventral nerve cord,proboscis,embryonic/larval muscle system,dorsal appendage,ovariole,germline clone,Tv neuron,neuroblast NB3-3,EL neuron,supernumerary,adult antennal lobe projection neuron DM5 lPN,somatic clone,wing hinge,tarsal segment,ventral nerve cord commissure,longitudinal connective" FBgn0060395 l(3)S132312 lethal (3) S132312 http://flybase.net/reports/FBgn0060395.html gene 1323/12 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0027625 tx-like taxi-like http://flybase.net/reports/FBgn0027625.html gene "Txl, txl" 16-Dec-15 2015_12 "viable,partially lethal - majority live,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0005399 costakink costakink http://flybase.net/reports/FBgn0005399.html "FBgn0000381, FBgn0001481, FBgn0001482" gene "l(1)10Aa, l(1)10Ab, 68, l(1)G6, l(1)BP4, l(1)F120, l(1)L68, csk, l(1)dsS53" 16-Dec-15 2015_12 "lethal,heat sensitive,visible,partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,male,female,reduced,male fertile,female fertile,lethal - all die before end of larval stage,some die during larval stage" "costal vein,wing,wing vein L1,eye" FBgn0033692 wash washout http://flybase.net/reports/FBgn0033692.html protein_coding_gene "0051020=GTPase binding, 0043014=alpha-tubulin binding, 0005515=protein binding" "0035277=spiracle morphogenesis, open tracheal system, 0035210=prepupal development, 0001578=microtubule bundle formation, 0042147=retrograde transport, endosome to Golgi, 0048477=oogenesis, 0051017=actin filament bundle assembly, 0034314=Arp2/3 complex-mediated actin nucleation, 0051764=actin crosslink formation" "0005737=cytoplasm, 0005768=endosome, 0048471=perinuclear region of cytoplasm, 0071203=WASH complex, 0005634=nucleus, 0031941=filamentous actin, 0005769=early endosome, 0005667=transcription factor complex" "p65, Wash, p63, CG13176" "IPR028290=WASH1, IPR021854=WASH1, WAHD domain" CG13176 16-Dec-15 2015_12 ENSDARG00000063457(wash) WBGene00013000(ddl-2) ENSXETG00000003630(TNeu121a17.1) ENSMUSG00000024101(ORF19) "ENSG00000185596,ENSG00000182484,ENSG00000181404,ENSG00000155352" "viable,fertile,visible,recessive,large body,cell lethal,germline clone,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die during embryonic stage" "anterior pupal spiracle,prepupa,embryonic/larval dorsal trunk,oocyte | oogenesis stage S7" FBgn0035670 CG10472 http://flybase.net/reports/FBgn0035670.html FBgn0044783 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP78, anon-WO0140519.101" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG10472 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable DRSC25310 K 0.233552443 0.563572955 0.231570206 0.055564297 -0.193515758 1.733716112 FBgn0082598 akirin akirin http://flybase.net/reports/FBgn0082598.html "FBgn0035773, FBgn0062043" protein_coding_gene "0003712=transcription cofactor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0005515=protein binding" "0016203=muscle attachment, 0045088=regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0007526=larval somatic muscle development, 0045089=positive regulation of innate immune response, 0007517=muscle organ development, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005700=polytene chromosome, 0005719=nuclear euchromatin, 0035060=brahma complex" "Akirin, anon-WO0118547.397, bhringi, DmAkirin, EP(3)0906, bhr, CG8580" IPR024132=Akirin CG8580 16-Dec-15 2015_12 "ENSDARG00000058729(akirin2),ENSDARG00000039969(akirin1)" WBGene00017088(E01A2.6) "ENSXETG00000019800(TEgg001a06.1),ENSXETG00000005271(TGas103l22.1)" "ENSMUSG00000028291(Akirin2),ENSMUSG00000023075(Akirin1)" "ENSG00000135334(AKIRIN2),ENSG00000174574(AKIRIN1)" "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,immune response defective" embryonic/larval somatic muscle FBgn0030882 GSS Glutathione Synthetase http://flybase.net/reports/FBgn0030882.html "FBgn0052497, FBgn0053065" protein_coding_gene "0004363=glutathione synthase activity, 0005524=ATP binding" "0006974=cellular response to DNA damage stimulus, 0071722=detoxification of arsenic-containing substance, 0045471=response to ethanol, 0006750=glutathione biosynthetic process" "GS, 6835, CG33065, CG6835, glutathione synthetase, CG32497, Glutathione Synthase" "IPR013816=ATP-grasp fold, subdomain 2, IPR016185=Pre-ATP-grasp domain, IPR014709=Glutathione synthase domain, IPR005615=Glutathione synthase, eukaryotic, IPR014049=Glutathione synthase, N-terminal, eukaryotic, IPR014042=Glutathione synthase, alpha-helical, eukaryotic, IPR004887=Glutathione synthase, substrate-binding, eukaryotic" CG6835 16-Dec-15 2015_12 ENSDARG00000037706(LOC100332067) YOL049W(GSH2) WBGene00010941(M176.2) ENSXETG00000007470(GSS) ENSMUSG00000027610(Gss) ENSG00000100983(GSS) FBgn0003116 pn prune http://flybase.net/reports/FBgn0003116.html protein_coding_gene "0004112=cyclic-nucleotide phosphodiesterase activity, 0016462=pyrophosphatase activity" "0001745=compound eye morphogenesis, 0019889=pteridine metabolic process, 0006198=cAMP catabolic process, 0090297=positive regulation of mitochondrial DNA replication, 0048072=compound eye pigmentation, 0043951=negative regulation of cAMP-mediated signaling" 0005759=mitochondrial matrix "transcription unit II, TcD37, N3, CG3461, EG:152A3.5, se-like-62, N4" "IPR001667=DDH domain, IPR004097=DHHA2 domain" CG3461 16-Dec-15 2015_12 YHR201C(PPX1) "ENSXETG00000008118(PRUNE),ENSXETG00000003615()" "ENSMUSG00000015711(Prune),ENSMUSG00000054366" ENSG00000143363(PRUNE) embryonic stage -- adult stage "visible,recessive,eye color defective,wild-type,lethal,heat sensitive,viable" "pigment cell,heat sensitive" FBgn0033214 CG1941 http://flybase.net/reports/FBgn0033214.html protein_coding_gene "0016747=transferase activity, transferring acyl groups other than amino-acyl groups" IPR007130=Diacylglycerol acyltransferase CG1941 16-Dec-15 2015_12 "ENSDARG00000019228(mogat2),ENSDARG00000018846(dgat2),ENSDARG00000003635(LOC565116),ENSDARG00000070072" YOR245C(DGA1) "WBGene00019464(K07B1.4),WBGene00021818(Y53G8B.2),WBGene00020910(W01A11.2),WBGene00010296(F59A1.10)" "ENSXETG00000002935(mogat1),ENSXETG00000004012(mogat2),ENSXETG00000015062(),ENSXETG00000023190(),ENSXETG00000025317(dgat2)" "ENSMUSG00000052396(Mogat2),ENSMUSG00000012187(Mogat1),ENSMUSG00000030747(Dgat2),ENSMUSG00000067597(Dgat2l6),ENSMUSG00000031220(Awat2),ENSMUSG00000015665(Awat1)" "ENSG00000166391(MOGAT2),ENSG00000124003(MOGAT1),ENSG00000062282(DGAT2),ENSG00000106384(MOGAT3),ENSG00000204195(AWAT1),ENSG00000184210(DGAT2L6),ENSG00000147160(AWAT2)" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0037569 tex tex http://flybase.net/reports/FBgn0037569.html protein_coding_gene 0005875=microtubule associated complex "TEX1, CG9615" "IPR020472=G-protein beta WD-40 repeat, IPR011659=WD40-like Beta Propeller, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG9615 16-Dec-15 2015_12 ENSDARG00000056517(thoc3) YNL253W(TEX1) WBGene00009341(thoc-3) ENSXETG00000022316(THOC3) ENSMUSG00000025872(Thoc3) "ENSG00000051596(THOC3),ENSG00000170089" viable FBgn0031535 CG12795 http://flybase.net/reports/FBgn0031535.html protein_coding_gene 0008270=zinc ion binding "IPR000058=Zinc finger, AN1-type" CG12795 16-Dec-15 2015_12 ENSDARG00000003283(zfand2a) WBGene00000097(aip-1) ENSXETG00000004023(Egg005f01.1) ENSMUSG00000026197(Zfand2b) ENSG00000158552(ZFAND2B) viable FBgn0008636 hbn homeobrain http://flybase.net/reports/FBgn0008636.html "FBgn0034561, FBgn0034562, FBgn0040654, FBgn0053152" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated" 0005634=nucleus "Homeobrain, CG33152, CG15648, Hbn, CG15647, 57San, CG10614" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG33152 16-Dec-15 2015_12 ENSMUSG00000012520(Phox2b) "lethal - all die before end of embryonic stage,some die during embryonic stage" DRSC04239 I -0.426737378 -1.676481605 -1.395950196 0.085083122 -0.491667623 0.193891244 FBgn0052062 A2bp1 Ataxin-2 binding protein 1 http://flybase.net/reports/FBgn0052062.html "FBgn0036086, FBgn0036087" protein_coding_gene "0003729=mRNA binding, 0008134=transcription factor binding, 0000166=nucleotide binding, 0044212=transcription regulatory region DNA binding" "0048477=oogenesis, 0045893=positive regulation of transcription, DNA-templated, 0007399=nervous system development, 0007474=imaginal disc-derived wing vein specification" "0005634=nucleus, 0005737=cytoplasm, 0005654=nucleoplasm" "CG32062, CG14155, Ataxin-2 Binding Protein 1, cg18441, dA2BP1, BcDNA:GM06073, CG18441, A2BP1" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG32062 16-Dec-15 2015_12 "ENSDARG00000014746(a2bp1),ENSDARG00000021184(a2bp1l),ENSDARG00000052182(rbm9),ENSDARG00000010083" WBGene00011279(asd-1) "ENSMUSG00000025576(D11Bwg0517e),ENSMUSG00000008658(A2bp1),ENSMUSG00000033565(Rbm9)" "ENSG00000167281(RBFOX3),ENSG00000078328(RBFOX1),ENSG00000100320(RBFOX2)" "female sterile,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal,oxidative stress response defective,female fertile,female semi-sterile,fertile" "ovary,wing cell,crossvein,ectopic,wing vein L3,wing vein L4,wing vein,somatic clone,nurse cell,female germline cell,germline clone" FBgn0022987 qkr54B quaking related 54B http://flybase.net/reports/FBgn0022987.html FBgn0025570 protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding" 0005737=cytoplasm "QKR54B, qrk54B, SAM50, p62GAP, Sam50, CG4816, SAM" "IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG4816 16-Dec-15 2015_12 "ENSDARG00000069469(khdrbs2),ENSDARG00000070475(khdrbs1b),ENSDARG00000052856(khdrbs1a),ENSDARG00000063548" "WBGene00013325(Y57G11C.36),WBGene00019509(K07H8.9)" "ENSXETG00000004451(KHDRBS2),ENSXETG00000009227(KHDRBS3),ENSXETG00000005246(pcbp2)" "ENSMUSG00000022332(Khdrbs3),ENSMUSG00000026058(Khdrbs2),ENSMUSG00000028790(Khdrbs1)" "ENSG00000131773(KHDRBS3),ENSG00000112232(KHDRBS2),ENSG00000121774(KHDRBS1)" " adult stage | female , embryonic stage | 0-4 hr , oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

viable FBgn0029783 Sirt4 Sirtuin 4 http://flybase.net/reports/FBgn0029783.html protein_coding_gene "0070403=NAD+ binding, 0004407=histone deacetylase activity" 0016575=histone deacetylation 0005739=mitochondrion "D.mel3, CG3187, Sirt4, dmSRT407, dSIRT4" "IPR026590=Sirtuin family, catalytic core domain, IPR026591=Sirtuin family, catalytic core small domain, IPR026587=Sirtuin, class II, IPR003000=Sirtuin family, IPR029035=DHS-like NAD/FAD-binding domain" CG3187 16-Dec-15 2015_12 ENSDARG00000010415(zgc:103539) "WBGene00004801(sir-2.2),WBGene00004802(sir-2.3)" ENSXETG00000004254(sirt4) ENSMUSG00000029524(Sirt4) ENSG00000089163(SIRT4) viable FBgn0040257 Ugt86Dc Ugt86Dc http://flybase.net/reports/FBgn0040257.html FBgn0037864 protein_coding_gene "0015020=glucuronosyltransferase activity, 0003851=2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity" 0008152=metabolic process "AC 006491C, CG4739" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG4739 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" "viable,fertile" FBgn0005585 Calr Calreticulin http://flybase.net/reports/FBgn0005585.html "FBgn0022988, FBgn0025188" protein_coding_gene "0005509=calcium ion binding, 0051082=unfolded protein binding" "0006457=protein folding, 0022008=neurogenesis, 0007422=peripheral nervous system development, 0007417=central nervous system development, 0031987=locomotion involved in locomotory behavior, 0001964=startle response, 0007476=imaginal disc-derived wing morphogenesis, 0030431=sleep, 0048854=brain morphogenesis, 0042048=olfactory behavior" "0012505=endomembrane system, 0005811=lipid particle, 0045169=fusome, 0005615=extracellular space, 0005788=endoplasmic reticulum lumen" "pot pourri, clone 2.17, chr3R:5454619..5454778, eth, calreticulin, potp, clone 2.11, crc, anon-EST:Liang-2.11, anon-EST:Liang-2.17, CG9429, Clr, anon-fast-evolving-3D7, unnamed, anon-EST:fe3D7, Crc, potpourri" "IPR009033=Calreticulin/calnexin, P domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR009169=Calreticulin, IPR018124=Calreticulin/calnexin, conserved site, IPR001580=Calreticulin/calnexin" CG9429 16-Dec-15 2015_12 "ENSDARG00000024973(calrl2),ENSDARG00000043276(calr),ENSDARG00000020103(calrl)" WBGene00000802(crt-1) ENSXETG00000007937(calr) ENSMUSG00000003814(Calr) ENSG00000179218(CALR) "viable,lethal,recessive,smell perception defective,fertile,sleep defective,chemical sensitive,chemical resistant,neuroanatomy defective" "macrochaeta,neuron,presumptive embryonic/larval peripheral nervous system,embryonic/larval neuroblast,ganglion mother cell" FBgn0037531 CG10445 http://flybase.net/reports/FBgn0037531.html protein_coding_gene 0005524=ATP binding "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR014001=Helicase superfamily 1/2, ATP-binding domain" CG10445 16-Dec-15 2015_12 ENSDARG00000026053(LOC564651) YOR191W(ULS1) "WBGene00020742(T23H2.3),WBGene00010061(F54E12.2),WBGene00019095(F59A7.8)" viable FBgn0015010 Ag5r Antigen 5-related http://flybase.net/reports/FBgn0015010.html "FBgn0030580, FBgn0044553" protein_coding_gene 0005576=extracellular region "agr, antigen 5-related, Agr5, anon-WO0140519.74, CG9538, Agr" "IPR014044=CAP domain, IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG9538 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" " adult stage | female , embryonic stage -- adult stage , adult stage | male " viable FBgn0036446 CG9384 http://flybase.net/reports/FBgn0036446.html protein_coding_gene "0008454=alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity" 0005975=carbohydrate metabolic process 0016020=membrane dMGAT4-1 IPR006759=Glycosyl transferase family 54 CG9384 16-Dec-15 2015_12 "ENSDARG00000063330(LOC563038),ENSDARG00000004115(mgat4b)" "ENSXETG00000011234(MGAT4B),ENSXETG00000019401(MGAT4A),ENSXETG00000014915()" "ENSMUSG00000036620(Mgat4b),ENSMUSG00000026110(Mgat4a)" "ENSG00000161013(MGAT4B),ENSG00000071073(MGAT4A)" viable FBgn0040250 Ugt86Dj Ugt86Dj http://flybase.net/reports/FBgn0040250.html FBgn0037868 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "unnamed, AC 006491J, CG15902" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG15902 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00007946(ugt-33),WBGene00013904(ugt-6),WBGene00009255(ugt-34),WBGene00013906(ugt-5),WBGene00044286(ugt-35),WBGene00013905(ugt-4),WBGene00017333(ugt-38),WBGene00017329(ugt-39),WBGene00017332(ugt-37),WBGene00017959(ugt-42),WBGene00017336(ugt-41),WBGene00017315(ugt-36),WBGene00017331(ugt-40),WBGene00015739(ugt-7),WBGene00017337(F10D2.12)" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0050486 CG30486 http://flybase.net/reports/FBgn0050486.html protein_coding_gene 0032504=multicellular organism reproduction "0005576=extracellular region, 0005615=extracellular space" "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG30486 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0036999 isoQC iso Glutaminyl cyclase http://flybase.net/reports/FBgn0036999.html FBgn0052426 protein_coding_gene 0016603=glutaminyl-peptide cyclotransferase activity "0017186=peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase" "0005739=mitochondrion, 0005576=extracellular region" "CG5976, CG32426, isoDromeQC" IPR007484=Peptidase M28 CG5976 16-Dec-15 2015_12 "ENSDARG00000060776,ENSDARG00000061691(si:dkey-149j18.2),ENSDARG00000062293(LOC564655)" YFR018C() "ENSXETG00000013098(qpct(prov)),ENSXETG00000018261(QPCTL)" "ENSMUSG00000024084(Qpct),ENSMUSG00000030407(Qpctl)" "ENSG00000115828(QPCT),ENSG00000011478(QPCTL)" FBgn0030391 Rab40 Rab40 http://flybase.net/reports/FBgn0030391.html protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "0008360=regulation of cell shape, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport, 0015031=protein transport" 0031982=vesicle "DmRab40, rab40, 24641533, Q8IR80, CG1900" "IPR001496=SOCS box domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001806=Small GTPase superfamily, IPR005225=Small GTP-binding protein domain, IPR003579=Small GTPase superfamily, Rab type" CG1900 16-Dec-15 2015_12 "ENSDARG00000061208(rab40c),ENSDARG00000042410(rab40b)" ENSXETG00000022807() "ENSMUSG00000025730(Rab40c),ENSMUSG00000025170(Rab40b)" "ENSG00000197562(RAB40C),ENSG00000141542(RAB40B),ENSG00000102128(RAB40AL),ENSG00000172476(RAB40A)" "viable,fertile" DRSC19820 IE 2.394000745 1.249831291 2.524947784 0.722026501 0.483577515 -0.522709581 FBgn0028990 Spn27A Serpin 27A http://flybase.net/reports/FBgn0028990.html FBgn0031846 protein_coding_gene "0004867=serine-type endopeptidase inhibitor activity, 0004857=enzyme inhibitor activity" "0010951=negative regulation of endopeptidase activity, 0050832=defense response to fungus, 0048149=behavioral response to ethanol, 0035009=negative regulation of melanization defense response, 0035006=melanization defense response, 0008063=Toll signaling pathway, 0009950=dorsal/ventral axis specification, 0009611=response to wounding, 0002213=defense response to insect, 0035011=melanotic encapsulation of foreign target, 0045861=negative regulation of proteolysis" "0005615=extracellular space, 0005576=extracellular region" "Serpin-27A, Spn27a, Dm-Spn27A, serpin27A, sp27A, Dm-serpin-27A, CG11331, serpin 27A, Serpin27A, spn27A, Serpin 27A, Spn27, serpin-27A, EST1" "IPR023796=Serpin domain, IPR023795=Serpin, conserved site, IPR000215=Serpin family" CG11331 16-Dec-15 2015_12 "lethal,maternal effect,viable,body color defective,hypoactive,conditional,chemical resistant,melanotic mass phenotype,immune response defective,lethal - all die before end of pupal stage,partially,some die during pupal stage,female sterile,recessive,partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic dorsal epidermis,embryonic epidermis,embryonic/first instar larval cuticle,maternal effect,wing,melanotic mass,trachea,embryonic/larval hemolymph | third instar larval stage" FBgn0003742 tra2 transformer 2 http://flybase.net/reports/FBgn0003742.html protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0005515=protein binding, 0042802=identical protein binding, 0036002=pre-mRNA binding" "0006397=mRNA processing, 0019101=female somatic sex determination, 0019102=male somatic sex determination, 0048024=regulation of mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0000245=spliceosomal complex assembly, 0007530=sex determination, 0030237=female sex determination, 0007283=spermatogenesis, 0000003=reproduction, 0000398=mRNA splicing, via spliceosome" 0071011=precatalytic spliceosome "transformer-2, TRA2, TRA 2, tra-2, Transformer 2, Transformer-2, CG10128, TRA-2, Tra-2, transformer2, Tra2" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG10128 16-Dec-15 2015_12 "ENSDARG00000002168(tra2b),ENSDARG00000007863(tra2a)" WBGene00004705(rsp-8) "ENSXETG00000007397(BC074599.1),ENSXETG00000007511(sfrs10)" "ENSMUSG00000029817(Tra2a),ENSMUSG00000022858(Tra2b)" "ENSG00000164548(TRA2A),ENSG00000136527(TRA2B)" " adult stage | female , adult stage | male " " testis

, germline cell

" "visible,heat sensitive,viable,sex-determination defective,male fertile,sterile,recessive,courtship behavior defective,female,lethal,female fertile,wild-type,male sterile,female sterile" "female genitalia,sex comb,spermatozoon,ectopic,female,female reproductive system,spermatocyte,spermatid,gonad,germline cell,heat sensitive,male repressed primordium,somatic clone,male genitalia,female analia,ovary,abdominal tergite 6,abdominal tergite 7,abdominal tergite 5,abdominal sternite 6,anal plate,female genital disc,male genital disc,adult abdomen" FBgn0036000 CG3434 http://flybase.net/reports/FBgn0036000.html protein_coding_gene 0008479=queuine tRNA-ribosyltransferase activity 0008616=queuosine biosynthetic process "IPR028592=Queuine tRNA-ribosyltransferase subunit QTRTD1, IPR002616=tRNA-guanine(15) transglycosylase-like" CG3434 16-Dec-15 2015_12 ENSDARG00000016093(qtrtd1) WBGene00006567(tgt-2) ENSXETG00000002805(qtrtd1(prov)) ENSMUSG00000022704(Qtrtd1) ENSG00000151576(QTRTD1) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0083084 l(2)42Ac l(2)42Ac http://flybase.net/reports/FBgn0083084.html gene 16-Dec-15 2015_12 "lethal,recessive" "wing,microchaeta" FBgn0016919 nompB no mechanoreceptor potential B http://flybase.net/reports/FBgn0016919.html "FBgn0032950, FBgn0032951, FBgn0032952, FBgn0032953" protein_coding_gene "0008104=protein localization, 0007605=sensory perception of sound, 0042073=intraciliary transport, 0042384=cilium assembly, 0035058=nonmotile primary cilium assembly, 0060271=cilium morphogenesis" "0030990=intraciliary transport particle, 0031513=nonmotile primary cilium, 0005929=cilium, 0030992=intraciliary transport particle B" "nomp, IFT88, 146590_s_at, NompB, OSM-5, Tg737, CG12548, CG15190, osm-5, CG14465, CG4137, NOMPB" "IPR019734=Tetratricopeptide repeat, IPR011990=Tetratricopeptide-like helical domain, IPR013026=Tetratricopeptide repeat-containing domain" CG12548 16-Dec-15 2015_12 ENSDARG00000027234(ift88) WBGene00003885(osm-5) ENSMUSG00000040040(Ift88) ENSG00000032742(IFT88) " olfactory sensory organ

, mechanosensory chaeta

, sensillum campaniformium

, chordotonal organ

" "auditory perception defective,recessive,uncoordinated,locomotor behavior defective,behavior defective,fertile,partially lethal - majority die,flight defective,viable" "wing,leg,macrochaeta,adult antennal nerve,scolopidial cilium,cilium & olfactory neuron & antennal segment 3,ciliumpeb-,olfactory receptor neuron" FBgn0037555 Ada2b transcriptional Adaptor 2b http://flybase.net/reports/FBgn0037555.html protein_coding_gene "0008270=zinc ion binding, 0005515=protein binding, 0004402=histone acetyltransferase activity, 0003677=DNA binding" "0006355=regulation of transcription, DNA-templated, 0035222=wing disc pattern formation, 2000331=regulation of terminal button organization, 0035079=polytene chromosome puffing, 0043966=histone H3 acetylation, 0006357=regulation of transcription from RNA polymerase II promoter, 0007412=axon target recognition, 0006338=chromatin remodeling, 0035066=positive regulation of histone acetylation" "0005634=nucleus, 0005700=polytene chromosome, 0000124=SAGA complex" "dAda2b, Ada2b, BcDNA:LD24527, dAda2B, CG9638, ada2b, Ada2B, dAda2S, ADA2b, dADA2b, Ada2S, Transcriptional adapter 2S" "IPR016827=Transcriptional adaptor 2, IPR000433=Zinc finger, ZZ-type, IPR001005=SANT/Myb domain, IPR009057=Homeodomain-like, IPR017884=SANT domain" CG9638 16-Dec-15 2015_12 ENSDARG00000003769(tada2b) YDR448W(ADA2) WBGene00017967(ada-2) ENSXETG00000022903(TADA2B) ENSMUSG00000029196 ENSG00000173011(TADA2B) "lethal,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,germline clone,recessive,neuroanatomy defective,visible,partially lethal - majority die" "axon & photoreceptor cell R2,axon & photoreceptor cell R3,axon & photoreceptor cell R4,axon & photoreceptor cell R5,glial cell,wing disc,conditional,trichogen cell" FBgn0027359 Tim8 Tim8 http://flybase.net/reports/FBgn0027359.html FBgn0062891 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity "0006626=protein targeting to mitochondrion, 0015031=protein transport" "0005744=mitochondrial inner membrane presequence translocase complex, 0005739=mitochondrion" "CG1728, BcDNA:SD06593" IPR004217=Tim10/DDP family zinc finger CG1728 16-Dec-15 2015_12 ENSDARG00000055708(timm8b) YJR135W-A(TIM8) WBGene00000941(ddp-1) ENSXETG00000027681(timm8b) ENSMUSG00000039016(Timm8b) ENSG00000150779(TIMM8B) viable eye FBgn0033906 CG8331 http://flybase.net/reports/FBgn0033906.html protein_coding_gene 0012505=endomembrane system CT24597 IPR004345=TB2/DP1/HVA22-related protein CG8331 16-Dec-15 2015_12 "ENSDARG00000052661(reep5),ENSDARG00000038694(zgc:101744),ENSDARG00000042965(reep6)" YPR028W(YOP1) WBGene00022127(yop-1) "ENSXETG00000021513(TNeu028a23.1),ENSXETG00000003708(TGas053h05.1)" ENSMUSG00000005873(Reep5) ENSG00000129625(REEP5) "viable,fertile" FBgn0034081 CG10731 http://flybase.net/reports/FBgn0034081.html "FBgn0053038, FBtr0087251, FBpp0086389, FBtr0087252, FBpp0086390, FBtr0087253, FBpp0086391" protein_coding_gene "0008553=hydrogen-exporting ATPase activity, phosphorylative mechanism" 0015992=proton transport "0000276=mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)" "ATP synthase coupling factor B, CG33038, ATPW" "IPR026063=ATP synthase subunit s, mitochondrial" CG10731 16-Dec-15 2015_12 ENSDARG00000012072(atp5s) WBGene00015460(C05C8.1) ENSXETG00000019713(ATP5S) ENSMUSG00000054894(Atp5s) ENSG00000125375(ATP5S) FBgn0032157 Etl1 Etl1 homologue http://flybase.net/reports/FBgn0032157.html protein_coding_gene "0004003=ATP-dependent DNA helicase activity, 0005524=ATP binding" "0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response" "CG5899, Etl1" "IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR000330=SNF2-related, N-terminal domain" CG5899 16-Dec-15 2015_12 ENSDARG00000014041(zgc:113183) YAL019W(FUN30) WBGene00010845(M03C11.8) ENSXETG00000019214(smarcad1) ENSMUSG00000029920(Smarcad1) ENSG00000163104(SMARCAD1) "suppressor of variegation,viable" embryonic/larval hemocyte | third instar larval stage FBgn0034491 Hsl Hormone-sensitive lipase ortholog http://flybase.net/reports/FBgn0034491.html FBgn0014915 protein_coding_gene 0004806=triglyceride lipase activity "0008203=cholesterol metabolic process, 0006642=triglyceride mobilization, 0016042=lipid catabolic process" "0005811=lipid particle, 0005829=cytosol" "transcription unit A, A, Hormone sensitive lipase, anon-56Ea, dHSL, CG11055, Hormone-sensitive lipase" "IPR013094=Alpha/beta hydrolase fold-3, IPR010468=Hormone-sensitive lipase, N-terminal, IPR029058=Alpha/Beta hydrolase fold" CG11055 16-Dec-15 2015_12 ENSDARG00000063037(si:dkey-3n22.7) WBGene00016704(C46C11.1) ENSMUSG00000003123(Lipe) ENSG00000079435(LIPE) viable "embryonic/larval fat body,lipid particle" FBgn0035619 CG10592 http://flybase.net/reports/FBgn0035619.html protein_coding_gene 0004035=alkaline phosphatase activity 0016311=dephosphorylation 0009986=cell surface "IPR017850=Alkaline-phosphatase-like, core domain, IPR001952=Alkaline phosphatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG10592 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSMUSG00000028766(Alpl),ENSMUSG00000026246(Alppl2),ENSMUSG00000079440(Alpi),ENSMUSG00000036500(Akp3)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" "viable,fertile" FBgn0013954 FK506-bp2 FK506-binding protein 2 http://flybase.net/reports/FBgn0013954.html protein_coding_gene "0005528=FK506 binding, 0003755=peptidyl-prolyl cis-trans isomerase activity" "0006974=cellular response to DNA damage stimulus, 0018208=peptidyl-proline modification, 0006457=protein folding" "0005737=cytoplasm, 0005886=plasma membrane, 0016020=membrane" "fkbp, 143729_at, DrFKBP12, dFKBP12, 11001, FKBP12, FKBP, FK506-binding protein, Fk506-bp2, CG11001" "IPR001179=FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566=Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG11001 16-Dec-15 2015_12 "ENSDARG00000022684(zgc:73373),ENSDARG00000033567(zgc:103752),ENSDARG00000052625" YNL135C(FPR1) WBGene00001427(fkb-2) ENSXETG00000026101(FKBP1B) ENSMUSG00000020635(Fkbp1b) "ENSG00000088832(FKBP1A),ENSG00000198225,ENSG00000119782(FKBP1B)" viable FBgn0037146 CG7470 http://flybase.net/reports/FBgn0037146.html protein_coding_gene "0004350=glutamate-5-semialdehyde dehydrogenase activity, 0004349=glutamate 5-kinase activity, 0017084=delta1-pyrroline-5-carboxylate synthetase activity" "0055114=oxidation-reduction process, 0006561=proline biosynthetic process, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation" "0005743=mitochondrial inner membrane, 0005739=mitochondrion, 0005811=lipid particle" "glutamate 5-kinase, Glutamate 5-kinase" "IPR005715=Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase, IPR016162=Aldehyde dehydrogenase N-terminal domain, IPR015590=Aldehyde dehydrogenase domain, IPR016161=Aldehyde/histidinol dehydrogenase, IPR001057=Glutamate/acetylglutamate kinase, IPR020593=Gamma-glutamyl phosphate reductase GPR, conserved site, IPR005766=Delta l-pyrroline-5-carboxylate synthetase, IPR001048=Aspartate/glutamate/uridylate kinase, IPR019797=Glutamate 5-kinase, conserved site, IPR016163=Aldehyde dehydrogenase, C-terminal, IPR000965=GPR domain" CG7470 16-Dec-15 2015_12 ENSDARG00000061123(LOC100332705) YOR323C(PRO2) WBGene00011938(alh-13) ENSXETG00000022613(aldh18a1) ENSMUSG00000025007(Aldh18a1) ENSG00000059573(ALDH18A1) viable "epithelium,egg chamber,interfollicle cell" FBgn0265935 coro coro http://flybase.net/reports/FBgn0265935.html "FBgn0033109, FBgn0022064" protein_coding_gene "0003779=actin binding, 0051015=actin filament binding" "0007527=adult somatic muscle development, 0050832=defense response to fungus, 0030036=actin cytoskeleton organization" "0015629=actin cytoskeleton, 0072686=mitotic spindle" "lethal (2) k08011, CG9446, coronin, l(2)k08011, Coronin" "IPR019775=WD40 repeat, conserved site, IPR015048=Domain of unknown function DUF1899, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR015505=Coronin, IPR017986=WD40-repeat-containing domain" CG9446 16-Dec-15 2015_12 "ENSDARG00000035598(coro1ca),ENSDARG00000021193(coro1cb),ENSDARG00000054610(coro1a),ENSDARG00000008660(coro1b)" YLR429W(CRN1) WBGene00000768(cor-1) "ENSXETG00000022312(CORO1C),ENSXETG00000021328(CORO6)" "ENSMUSG00000024835(Coro1b),ENSMUSG00000004530(Coro1c),ENSMUSG00000020836(Coro6),ENSMUSG00000030707(Coro1a)" "ENSG00000172725(CORO1B),ENSG00000110880(CORO1C),ENSG00000167549(CORO6),ENSG00000102879(CORO1A)" FBgn0035720 CG10077 http://flybase.net/reports/FBgn0035720.html "FBgn0047244, FBgn0063174" protein_coding_gene "0005524=ATP binding, 0003724=RNA helicase activity, 0003676=nucleic acid binding" 0005875=microtubule associated complex "BcDNA:HL01868, p90, BcDNA:HL07910, cg10077, DmRH5" "IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10077 16-Dec-15 2015_12 "ENSDARG00000038068(ddx5),ENSDARG00000010873(LOC556764)" YNL112W(DBP2) WBGene00010260(F58E10.3) "ENSXETG00000012580(ddx5),ENSXETG00000006900(ddx17)" "ENSMUSG00000020719(Ddx5),ENSMUSG00000055065(Ddx17)" "ENSG00000108654(DDX5),ENSG00000100201(DDX17)" "viable,fertile" FBgn0260748 CG5004 http://flybase.net/reports/FBgn0260748.html "FBgn0017445, FBgn0030820" protein_coding_gene "anon-15Db, transcript b" "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR008984=SMAD/FHA domain, IPR001849=Pleckstrin homology domain, IPR000253=Forkhead-associated (FHA) domain" CG5004 16-Dec-15 2015_12 ENSDARG00000061093(si:dkey-252h13.1) WBGene00021799(Y53G8AL.1) ENSXETG00000021556(PHLDB1) "ENSMUSG00000048537(Phldb1),ENSMUSG00000033149(Phldb2)" "ENSG00000019144(PHLDB1),ENSG00000144824(PHLDB2)" FBgn0036300 CG10688 http://flybase.net/reports/FBgn0036300.html protein_coding_gene 0004615=phosphomannomutase activity "0071456=cellular response to hypoxia, 0009298=GDP-mannose biosynthetic process, 0019307=mannose biosynthetic process" 0005737=cytoplasm 33589256 "IPR023214=HAD-like domain, IPR006379=HAD-superfamily hydrolase, subfamily IIB, IPR005002=Eukaryotic phosphomannomutase" CG10688 16-Dec-15 2015_12 ENSDARG00000037654(pmm2) YFL045C(SEC53) WBGene00009925(F52B11.2) "ENSXETG00000008692(PMM2),ENSXETG00000004549(PMM1)" "ENSMUSG00000022711(Pmm2),ENSMUSG00000022474(Pmm1)" "ENSG00000140650(PMM2),ENSG00000100417(PMM1)" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC09780 K 0.119947883 0.29477912 0.218179312 0.0659971 0.748016143 2.721494619 FBgn0029823 CG3011 http://flybase.net/reports/FBgn0029823.html FBgn0066862 protein_coding_gene "0004372=glycine hydroxymethyltransferase activity, 0030170=pyridoxal phosphate binding" "0048149=behavioral response to ethanol, 0006564=L-serine biosynthetic process, 0006544=glycine metabolic process" 0005739=mitochondrion "144561_at, Shmt2, anon-WO03040301.100, glycine hydroxylmethyltransferase" "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR019798=Serine hydroxymethyltransferase, pyridoxal phosphate binding site, IPR015424=Pyridoxal phosphate-dependent transferase, IPR001085=Serine hydroxymethyltransferase" CG3011 16-Dec-15 2015_12 ENSDARG00000052816(shmt1) "YLR058C(SHM2),YBR263W(SHM1)" WBGene00003214(mel-32) "ENSXETG00000017162(shmt2),ENSXETG00000005754(shmt1)" "ENSMUSG00000025403(Shmt2),ENSMUSG00000020534(Shmt1)" "ENSG00000182199(SHMT2),ENSG00000176974(SHMT1)" "viable,visible,hyperactive,conditional,chemical resistant" trichogen cell FBgn0263600 DNApol-ë« DNA-polymerase-ë« http://flybase.net/reports/FBgn0263600.html "FBgn0012066, FBgn0012067, FBgn0004714" protein_coding_gene "0003677=DNA binding, 0008310=single-stranded DNA 3'-5' exodeoxyribonuclease activity, 0003887=DNA-directed DNA polymerase activity, 0008296=3'-5'-exodeoxyribonuclease activity, 0000166=nucleotide binding" "0006273=lagging strand elongation, 0006272=leading strand elongation, 0006974=cellular response to DNA damage stimulus, 0022008=neurogenesis" "0043625=delta DNA polymerase complex, 0005875=microtubule associated complex" "5949, DNA-polymerase-delta, DNA polymerase-delta, dnapol delta, l(3)72Ac, CAA61369, Poldelta, CG5949, DNApol-delta, lethal (3) 72Ac, DNA Pol Delta, Dm Poldelta, DNA polymerase delta, DNA pol delta" "IPR025687=C4-type zinc-finger of DNA polymerase delta, IPR023211=DNA polymerase, palm domain, IPR017964=DNA-directed DNA polymerase, family B, conserved site, IPR006134=DNA-directed DNA polymerase, family B, multifunctional domain, IPR006172=DNA-directed DNA polymerase, family B, IPR012337=Ribonuclease H-like domain, IPR006133=DNA-directed DNA polymerase, family B, exonuclease domain" CG5949 16-Dec-15 2015_12 ENSDARG00000027689(pold1) YDL102W(POL3) WBGene00008645(F10C2.4) ENSXETG00000009036(POLD1) ENSMUSG00000038644(Pold1) ENSG00000062822(POLD1) FBgn0030893 RhoGAP16F Rho GTPase activating protein at 16F http://flybase.net/reports/FBgn0030893.html protein_coding_gene 0005096=GTPase activator activity "0007480=imaginal disc-derived leg morphogenesis, 0043547=positive regulation of GTPase activity" "CG7122, RhoGAP16F" "IPR015767=Rho GTPase activating protein, IPR000198=Rho GTPase-activating protein domain, IPR008936=Rho GTPase activation protein" CG7122 16-Dec-15 2015_12 "ENSDARG00000008548(arhgap12a),ENSDARG00000026482(arhgap12)" "ENSXETG00000017143(ARHGAP9),ENSXETG00000011657(ARHGAP12),ENSXETG00000003467(SH3D20)" viable FBgn0040098 lectin-29Ca lectin-29Ca http://flybase.net/reports/FBgn0040098.html FBgn0032038 protein_coding_gene "0005534=galactose binding, 0030246=carbohydrate binding" 0032504=multicellular organism reproduction 0005615=extracellular space "AC004423a, Lectin-29Ca, Acp29AB-I, AC 004423A, Lectin29Ca, CG17799" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG17799 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000008874(Clec3a),ENSMUSG00000025784(Clec3b),ENSMUSG00000004473(Clec11a)" ENSG00000163815(CLEC3B) FBgn0263832 Rcd5 Reduction in Cnn dots 5 http://flybase.net/reports/FBgn0263832.html "FBgn0011495, FBgn0035489" protein_coding_gene 0005515=protein binding "0007099=centriole replication, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint" "0044545=NSL complex, 0005634=nucleus, 0005730=nucleolus, 0005705=polytene chromosome interband" "MCRS1, lethal (3) rG166, Reduction in Cnn Dots 5, MCRS2, p78, l(3)rG166, l(3)r0166, CG1135, dMCRS1, dMCRS2" "IPR025999=Microspherule protein, N-terminal domain, IPR008984=SMAD/FHA domain, IPR000253=Forkhead-associated (FHA) domain" CG1135 16-Dec-15 2015_12 ENSDARG00000020840(mcrs1) WBGene00010420(H28O16.2) ENSXETG00000023241(mcrs1) ENSMUSG00000037570(Mcrs1) ENSG00000187778(MCRS1) "lethal,recessive,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" DRSC08180 E -0.420515883 0.003007192 -0.057181843 -4.635823709 0.797343734 -1.047486802 FBgn0035060 Eps-15 Epidermal growth factor receptor pathway substrate clone 15 http://flybase.net/reports/FBgn0035060.html FBgn0061582 protein_coding_gene 0005509=calcium ion binding "0048488=synaptic vesicle endocytosis, 0045746=negative regulation of Notch signaling pathway, 0006898=receptor-mediated endocytosis, 0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0008582=regulation of synaptic growth at neuromuscular junction" "0008021=synaptic vesicle, 0005737=cytoplasm" "anon-WO0118547.85, i31, EPS-15, Eps-15, EPS15, eps15, Eps15, EH1, Eps15 homologue 1, eps-15, CG16932" "IPR000261=EH domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG16932 16-Dec-15 2015_12 "ENSDARG00000042670(si:dkeyp-192m14.7),ENSDARG00000068282,ENSDARG00000067989" YBL047C(EDE1) WBGene00001224(ehs-1) "ENSXETG00000002074(EPS15L1),ENSXETG00000002833(EPS15)" "ENSMUSG00000006276(Eps15l1),ENSMUSG00000028552(Eps15)" "ENSG00000127527(EPS15L1),ENSG00000085832(EPS15)" "lethal,neuroanatomy defective,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,fertile,lethal - all die before end of pupal stage,some die during pupal stage,recessive,viable,lethal - all die before end of larval stage,some die during third instar larval stage" "glial cell,eye disc,embryonic/larval neuromuscular junction,bouton,supernumerary,macrochaeta,socket,eo sensory structure" FBgn0041194 Prat2 Phosphoribosylamidotransferase 2 http://flybase.net/reports/FBgn0041194.html FBgn0035717 protein_coding_gene 0004044=amidophosphoribosyltransferase activity "0009116=nucleoside metabolic process, 0006189='de novo' IMP biosynthetic process, 0009113=purine nucleobase biosynthetic process" "Phosphoribosylamidotransferase-2, Phosphoribosyl amidotransferase 2, DmPrat2, CG10078, Amidophosphoribosyltransferase" "IPR029057=Phosphoribosyltransferase-like, IPR005854=Amidophosphoribosyltransferase, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR017932=Glutamine amidotransferase type 2 domain, IPR000836=Phosphoribosyltransferase domain" CG10078 16-Dec-15 2015_12 ENSDARG00000004517(ppat) YMR300C(ADE4) WBGene00011407(T04A8.5) ENSXETG00000005618(Q6P2Z4_XENTR) ENSMUSG00000029246(Ppat) ENSG00000128059(PPAT) "female fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,partially,some die during pupal stage,viable" "head | P-stage,leg | P-stage,abdomen | P-stage,cephalopharyngeal skeleton | P-stage" FBgn0037008 mTerf3 http://flybase.net/reports/FBgn0037008.html protein_coding_gene "0003690=double-stranded DNA binding, 0070181=small ribosomal subunit rRNA binding" "0032543=mitochondrial translation, 1903108=regulation of transcription from mitochondrial promoter, 0051726=regulation of cell cycle, 0061668=mitochondrial ribosome assembly, 0006264=mitochondrial DNA replication, 0006390=transcription from mitochondrial promoter, 0070131=positive regulation of mitochondrial translation" 0005739=mitochondrion "DmMTERF3, MTERF3, DmMterf3, mitochondrial transcription termination factor, D-MTERF3, CG5047, Mterf3" IPR003690=Mitochodrial transcription termination factor CG5047 16-Dec-15 2015_12 ENSDARG00000003207(mterfd1) WBGene00008236(C50F4.12) ENSXETG00000014797(MTERFD3) ENSMUSG00000021519(Mterfd1) ENSG00000156469(MTERFD1) viable FBgn0260399 gwl greatwall http://flybase.net/reports/FBgn0260399.html "FBgn0004461, FBgn0038650, FBgn0082209, FBgn0015538" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0071889=14-3-3 protein binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0007144=female meiosis I, 0007067=mitotic nuclear division, 0046602=regulation of mitotic centrosome separation, 0030261=chromosome condensation, 0007088=regulation of mitotic nuclear division, 0007143=female meiotic division, 0007346=regulation of mitotic cell cycle, 0034048=negative regulation of protein phosphatase type 2A activity, 0006468=protein phosphorylation, 0040020=regulation of meiotic nuclear division" "0005635=nuclear envelope, 0005737=cytoplasm, 0005634=nucleus" "Greatwall, Pk?2, Protein kinase-like 91C, CT23435, CG7719, Pk91C, scott of the antarctic, 1J, CG7719-related, EP0515, scant, Gwl, anon-WO2004063362.73" "IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG7719 16-Dec-15 2015_12 ENSDARG00000055566(mastl) ENSXETG00000018741(MASTL) ENSMUSG00000026779(Mastl) ENSG00000120539(MASTL) FBgn0051368 CG31368 http://flybase.net/reports/FBgn0051368.html "FBgn0037959, FBgn0037961" protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0000974=Prp19 complex, 0071011=precatalytic spliceosome" "CG14730, CG14729" "IPR026300=CWF11 family, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG31368 16-Dec-15 2015_12 ENSDARG00000016775(zgc:63611) WBGene00001258(emb-4) ENSXETG00000012901(AQR) ENSMUSG00000040383(Aqr) ENSG00000021776(AQR) FBgn0051715 CG31715 http://flybase.net/reports/FBgn0051715.html FBgn0063012 protein_coding_gene BcDNA:RE44624 "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG31715 16-Dec-15 2015_12 ENSDARG00000055562(mtpn) WBGene00016616(C43H6.3) ENSXETG00000010610(MTPN) ENSMUSG00000029840(Mtpn) ENSG00000105887(MTPN) viable FBgn0263220 Hk Hyperkinetic http://flybase.net/reports/FBgn0263220.html "FBgn0001203, FBgn0030188, FBgn0052688, FBgn0085348" protein_coding_gene "0005249=voltage-gated potassium channel activity, 0015459=potassium channel regulator activity" "0007629=flight behavior, 0051259=protein oligomerization, 0050802=circadian sleep/wake cycle, sleep, 0006813=potassium ion transport" "0008076=voltage-gated potassium channel complex, 0005737=cytoplasm" "CG34319, Hyperk, Kvbeta channel subunit, CG2287, hk, CG43388, CG32688, CG17779, lincRNA.975, Hyperkinetic, Dm_X:51771" "IPR001395=Aldo/keto reductase, IPR005983=Potassium channel, voltage-dependent, beta subunit, KCNAB, IPR023210=NADP-dependent oxidoreductase domain, IPR005399=Potassium channel, voltage-dependent, beta subunit, KCNAB-related" CG43388 16-Dec-15 2015_12 "ENSDARG00000008140(kcnab1),ENSDARG00000040741(si:dkeyp-94h10.1),ENSDARG00000062134(zgc:171453)" "YNL331C(AAD14),YDL243C(AAD4),YCR107W(AAD3),YJR155W(AAD10),YPL088W()" "ENSXETG00000002894(KCNAB2),ENSXETG00000009066(KCNAB3),ENSXETG00000012263(KCNAB1)" "ENSMUSG00000028931(Kcnab2),ENSMUSG00000027827(Kcnab1),ENSMUSG00000018470(Kcnab3)" "ENSG00000069424(KCNAB2),ENSG00000169282(KCNAB1),ENSG00000170049(KCNAB3)" FBgn0053208 Mical Molecule interacting with CasL http://flybase.net/reports/FBgn0053208.html "FBgn0037774, FBgn0037775, FBgn0037776, FBgn0040538, FBgn0040539, FBgn0062839" protein_coding_gene "0003779=actin binding, 0043914=NADPH:sulfur oxidoreductase activity, 0008270=zinc ion binding" "0016322=neuron remodeling, 0019417=sulfur oxidation, 0007526=larval somatic muscle development, 0007015=actin filament organization, 0007411=axon guidance, 0030042=actin filament depolymerization, 0060386=synapse assembly involved in innervation, 0045214=sarcomere organization, 0070995=NADPH oxidation, 0048813=dendrite morphogenesis" "0043195=terminal bouton, 0005829=cytosol, 0005886=plasma membrane" "mical, milch, CG11685, CG33186, mdcds_49226, CG18667, CG33208, MICAL, CG18668, CG33190, CG18484, CG11687, molecule that interacts with CasL, molecule interacting with CasL, milchstrasse" "IPR001715=Calponin homology domain, IPR022735=Domain of unknown function DUF3585, IPR001781=Zinc finger, LIM-type, IPR029942=Mical, insect" CG33208 16-Dec-15 2015_12 "visible,lethal,neuroanatomy defective,flight defective,viable,fertile,flightless,somatic clone" "macrochaeta,filamentous actinB11-98,embryonic/larval somatic muscle | third instar larval stage,growth coneeve.RN2,intersegmental nerve,segmental nerve,embryonic/larval neuromuscular junction,bouton,myofibrilswp2MICAL),indirect flight muscle,embryonic/larval muscle system,sarcomere,embryonic/larval somatic muscle,filamentous actin | third instar larval stage,synapse,filamentous actin,abdominal segmental nerve,intersegmental nerve branch ISNb of A1-7,flight muscle,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,sarcomereMef2.PR,dendriteppk.1.9,dorsal multidendritic neuron ddaC,trichogen cell,dendrite221,somatic clone,dendrite,dendriteswp2MICAL)" DRSC15365 I 1.115290316 1.678497371 0.864773841 0.140537224 0.87533845 0.353451044 FBgn0011802 Gem3 Gemin3 http://flybase.net/reports/FBgn0011802.html FBgn0027895 protein_coding_gene "0003676=nucleic acid binding, 0003724=RNA helicase activity, 0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity" "0008344=adult locomotory behavior, 0007629=flight behavior, 0007528=neuromuscular junction development, 0022618=ribonucleoprotein complex assembly" "0005737=cytoplasm, 0015030=Cajal body, 0071254=cytoplasmic U snRNP body" "dGem3, DEAD/DEAH RNA helicase 1, gemin3, BcDNA.LD05563, DHH1, Gemin3, dGemin3, CG6539, l(3)rL562, DmRH22, Dhh1, BcDNA:LD05563, Gem3" "IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal, IPR011545=DEAD/DEAH box helicase domain" CG6539 16-Dec-15 2015_12 WBGene00020284(mel-46) ENSMUSG00000027905(Ddx20) "partially lethal - majority die,some die during pupal stage,lethal,viable,visible,gravitaxis defective,progressive,flightless,short lived,heat sensitive,flight defective,partially lethal - majority live,small body,locomotor behavior defective,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,developmental rate defective,partially" "trichogen cell,anterior pupal spiracle,puparium,embryonic/larval neuromuscular junction,embryonic/larval neuromuscular junction | larval stage,head | pupal stage,wing | pupal stage,leg | pupal stage,indirect flight muscle" FBgn0039627 CG11837 http://flybase.net/reports/FBgn0039627.html protein_coding_gene "0000179=rRNA (adenine-N6,N6-)-dimethyltransferase activity" "0000154=rRNA modification, 0022008=neurogenesis" "Dim1, FBgn0039627" "IPR001737=Ribosomal RNA adenine methyltransferase KsgA/Erm, IPR011530=Ribosomal RNA adenine dimethylase, IPR020598=Ribosomal RNA adenine methylase transferase, N-terminal, IPR020596=Ribosomal RNA adenine methylase transferase, conserved site, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG11837 16-Dec-15 2015_12 ENSDARG00000005057(zgc:101122) YPL266W(DIM1) WBGene00008455(E02H1.1) ENSXETG00000014830(DIMT1L) ENSMUSG00000021692(Dimt1) ENSG00000086189(DIMT1) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell" FBgn0040226 en::Su(H) en::Su(H) http://flybase.net/reports/FBgn0040226.html engineered_fusion_gene 16-Dec-15 2015_12 "planar polarity defective,somatic clone" "ommatidium,somatic clone,photoreceptor cell R7,lens,rhabdomere,eye photoreceptor cell,supernumerary" FBgn0039008 CG6972 http://flybase.net/reports/FBgn0039008.html protein_coding_gene 0003012=muscle system process CG6972 16-Dec-15 2015_12 "body color defective,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum DRSC16159 K 0.519120971 0.355086143 0.935898595 0.031468977 1.435592535 1.534828888 FBgn0014236 l(2)31Es lethal (2) 31Es http://flybase.net/reports/FBgn0014236.html gene 16-Dec-15 2015_12 "lethal,recessive" FBgn0026086 Adar Adenosine deaminase acting on RNA http://flybase.net/reports/FBgn0026086.html "FBgn0022736, FBgn0041575" protein_coding_gene "0003725=double-stranded RNA binding, 0003723=RNA binding, 0003726=double-stranded RNA adenosine deaminase activity" "0006382=adenosine to inosine editing, 0008049=male courtship behavior, 0042391=regulation of membrane potential, 0060964=regulation of gene silencing by miRNA, 0042752=regulation of circadian rhythm, 0001666=response to hypoxia, 0009451=RNA modification, 0009408=response to heat, 0007626=locomotory behavior, 0006396=RNA processing, 0045475=locomotor rhythm, 0030534=adult behavior, 0008344=adult locomotory behavior, 0016556=mRNA modification" "dAdar, hypnos-2, Adenosine deaminases acting on RNA, adar, ADAR, CG12598, adr, adenosine deaminase acting on RNA, cg12598, EG:BACN35H14.1, dADAR, ADAR1, hypoxia, anoxia, sensitive 2" "IPR014720=Double-stranded RNA-binding domain, IPR002466=Adenosine deaminase/editase" CG12598 16-Dec-15 2015_12 "ENSDARG00000041609(adarb1),ENSDARG00000003544(LOC558759),ENSDARG00000071823(adarb2)" WBGene00000080(adr-2) "ENSXETG00000018692(ADARB1),ENSXETG00000018065(ADARB2)" "ENSMUSG00000020262(Adarb1),ENSMUSG00000052551(Adarb2)" "ENSG00000197381(ADARB1),ENSG00000185736(ADARB2)" "locomotor rhythm defective,courtship behavior defective,gravitaxis defective,wild-type,partially lethal - majority die,paralytic,temperature conditional,viable,song defective,lethal,conditional,recessive,behavior defective,heat sensitive,male,grooming behavior defective,locomotor behavior defective,flight defective,uncoordinated,neurophysiology defective,dominant,stress response defective,heat stress response defective,short lived,neuroanatomy defective,partially lethal - majority live,visible,some die during pupal stage" "wing,adult central nervous system,medulla,lobula,lamina,type I bouton,synapse,neuromuscular junction,photoreceptor cell,adult brain,optic lobe,retina,heat sensitive,trichogen cell,mesothoracic tergum" DRSC17725 K 0.144107025 0.28952365 -0.587584984 0.000969972 3.060108026 1.808294074 FBgn0005221 l(3)ET16 lethal Elaine Tasaka 16 http://flybase.net/reports/FBgn0005221.html gene 16-Dec-15 2015_12 "lethal,heat sensitive,visible" wing FBgn0003085 pig pigmy http://flybase.net/reports/FBgn0003085.html gene pg 16-Dec-15 2015_12 "small body,viable,reduced,body color defective" FBgn0033693 CG13175 http://flybase.net/reports/FBgn0033693.html "FBgn0033694, FBgn0053154, FBtr0087990, FBpp0087098, FBtr0087991, FBpp0087099" protein_coding_gene CG33154 "IPR019191=Essential protein Yae1, N-terminal" CG13175 16-Dec-15 2015_12 ENSXETG00000013109(TEgg049b22.1) FBgn0026576 CG5991 http://flybase.net/reports/FBgn0026576.html FBgn0039143 protein_coding_gene 0004609=phosphatidylserine decarboxylase activity 0008654=phospholipid biosynthetic process "LD21713, Psd, BEST:LD21713, Phosphatidylserine decarboxylase" IPR003817=Phosphatidylserine decarboxylase-related CG5991 16-Dec-15 2015_12 ENSDARG00000052462(pisd) YNL169C(PSD1) WBGene00015159(psd-1) "ENSXETG00000004196(),ENSXETG00000018827(Q6GLA7_XENTR)" ENSMUSG00000023452(Pisd) ENSG00000100141 "partially lethal - majority die,visible,lethal,viable" "eye,tarsal segment" DRSC15935 I 0.297431888 3.844682968 0.101835545 0.077081268 -0.927764673 0.528120355 FBgn0025391 Scgë« Sarcoglycan ë« http://flybase.net/reports/FBgn0025391.html FBgn0047354 protein_coding_gene 0008307=structural constituent of muscle "0045214=sarcomere organization, 0007016=cytoskeletal anchoring at plasma membrane, 0060047=heart contraction, 0007498=mesoderm development" "0016021=integral component of membrane, 0016012=sarcoglycan complex, 0043034=costamere" "Sgcd, EG:4F1.1, DmSCG-gammadelta, Scgdelta, GH21860, CT34621, Sarcoglycan, CG14808, delta-sarcoglycan, BEST:GH21860" IPR006875=Sarcoglycan complex subunit protein CG14808 16-Dec-15 2015_12 "ENSDARG00000009789(sgcd),ENSDARG00000038107(sgcg)" WBGene00004790(sgn-1) "ENSXETG00000021081(SGCG),ENSXETG00000005641(SGCZ),ENSXETG00000023624(SGCD)" "ENSMUSG00000020354(Sgcd),ENSMUSG00000039539(Sgcz),ENSMUSG00000035296(Sgcg)" "ENSG00000170624(SGCD),ENSG00000185053(SGCZ),ENSG00000102683(SGCG)" "viable,short lived,gravitaxis defective" "adult heart,dorsal medial muscle,M band,sarcomere,indirect flight muscle" FBgn0046692 Stlk Ste20-like kinase http://flybase.net/reports/FBgn0046692.html "FBan0040293, FBgn0047227, FBgn0058293" protein_coding_gene "0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation "0005737=cytoplasm, 0005634=nucleus" "LD05623, CG40293, stlk, BcDNA:LD05623" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain" CG40293 16-Dec-15 2015_12 ENSDARG00000037929(strada) WBGene00013132(strd-1) "ENSXETG00000003248(lyk5),ENSXETG00000004143(STRADB)" "ENSMUSG00000069631(Strada),ENSMUSG00000026027(Stradb)" "ENSG00000125695(STRADA),ENSG00000082146(STRADB)" FBgn0014009 Rab2 Rab2 http://flybase.net/reports/FBgn0014009.html protein_coding_gene "0003924=GTPase activity, 0005515=protein binding, 0005525=GTP binding" "0015031=protein transport, 0032482=Rab protein signal transduction, 0016192=vesicle-mediated transport" "0043025=neuronal cell body, 0005886=plasma membrane, 0031982=vesicle" "rab2, DmRab2, DRAB2, Rab-protein 2, Drab2, DRab2, CG3269, O18333" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily, IPR003579=Small GTPase superfamily, Rab type" CG3269 16-Dec-15 2015_12 ENSDARG00000020261(rab2a) WBGene00006833(unc-108) ENSXETG00000020178() ENSMUSG00000047187(Rab2a) ENSG00000129472(RAB2B) " embryonic stage | stage 14-15 , embryonic stage -- adult stage , embryonic stage " " embryonic peripheral nervous system

, embryonic central nervous system

" "lethal,recessive,viable,immune response defective" "phagocytic vesicleHml.ëÓ,hemocyte | adult stage" FBgn0051954 CG31954 http://flybase.net/reports/FBgn0051954.html FBgn0031543 protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" 0006508=proteolysis "CG3229, SP107" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG31954 16-Dec-15 2015_12 "ENSDARG00000053315(tmprss3a),ENSDARG00000036545(LOC100003261),ENSDARG00000057040(tmprss13a)" "ENSXETG00000007733(BC087610.1),ENSXETG00000025357(BC087759.1),ENSXETG00000016566(BC087563.1),ENSXETG00000007734(),ENSXETG00000007732(BC089741.1),ENSXETG00000019241(BC075423.1),ENSXETG00000004320(BC088079.1),ENSXETG00000019309(BC087830.1),ENSXETG00000019305(),ENSXETG00000024870(BC088011.1),ENSXETG00000002940(BC087753.1)" "ENSMUSG00000057163(Prss2),ENSMUSG00000054106(Try4),ENSMUSG00000062751(Prss1),ENSMUSG00000071521(Try10),ENSMUSG00000071517(Gm10334),ENSMUSG00000071519(Prss3),ENSMUSG00000058119(Gm5771),ENSMUSG00000036938(Try5),ENSMUSG00000059014(Gm5409),ENSMUSG00000029882(2210010C04Rik),ENSMUSG00000036996(1810009J06Rik),ENSMUSG00000063252" "ENSG00000204982,ENSG00000204983(PRSS1),ENSG00000010438(PRSS3)" viable FBgn0034519 CG18065 http://flybase.net/reports/FBgn0034519.html "FBgn0053008, FBtr0086260, FBpp0085572, FBtr0086261, FBpp0085573, FBtr0086262, FBpp0085574" protein_coding_gene CG33008 CG18065 16-Dec-15 2015_12 ENSDARG00000055070(zgc:114169) ENSMUSG00000062376(2010012O05Rik) ENSG00000166275(C10orf32) DRSC06707 I -1.492973811 -1.901626673 -0.293269257 0.064279524 -0.943643027 -0.242055408 FBgn0029939 CG9650 http://flybase.net/reports/FBgn0029939.html protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" 0090278=negative regulation of peptide hormone secretion 0005829=cytosol "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG9650 16-Dec-15 2015_12 "ENSDARG00000061352(bcl11a),ENSDARG00000063153(si:ch211-127m10.2)" WBGene00017430(F13H6.1) "ENSXETG00000002206(BCL11A),ENSXETG00000011434(BCL11B)" "ENSMUSG00000000861(Bcl11a),ENSMUSG00000048251(Bcl11b)" "ENSG00000119866(BCL11A),ENSG00000127152(BCL11B)" "lethal,visible,recessive,viable,partially lethal - majority die" "ventral nerve cord commissure,longitudinal connective,eye,ommatidium,interommatidial bristle" FBgn0037713 CG16790 http://flybase.net/reports/FBgn0037713.html protein_coding_gene "0005515=protein binding, 0004518=nuclease activity" 0034477=U6 snRNA 3'-end processing "IPR009097=RNA ligase/cyclic nucleotide phosphodiesterase, IPR027521=U6 snRNA phosphodiesterase Usb1" CG16790 16-Dec-15 2015_12 ENSDARG00000003841(zgc:91896) ENSXETG00000013795(C16orf57) ENSMUSG00000031792(AA960436) ENSG00000103005(C16orf57) viable FBgn0032054 CG13090 http://flybase.net/reports/FBgn0032054.html protein_coding_gene "0004792=thiosulfate sulfurtransferase activity, 0071566=UFM1 activating enzyme activity" "0006777=Mo-molybdopterin cofactor biosynthetic process, 0002143=tRNA wobble position uridine thiolation, 0034227=tRNA thio-modification" "0005829=cytosol, 0019008=molybdopterin synthase complex" "Uba4 homologue, dMoaD" "IPR016040=NAD(P)-binding domain, IPR000594=THIF-type NAD/FAD binding fold, IPR028885=Adenylyltransferase and sulfurtransferase MOCS3/Uba4, IPR001763=Rhodanese-like domain" CG13090 16-Dec-15 2015_12 ENSDARG00000008239(mocs3) YHR111W(UBA4) WBGene00018357(moc-3) ENSXETG00000024648(MOCS3) ENSMUSG00000074576(Mocs3) ENSG00000124217(MOCS3) viable FBgn0053864 His1:CG33864 His1:CG33864 http://flybase.net/reports/FBgn0053864.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33864 "IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain" CG33864 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0028875 nAChRë±5 nicotinic Acetylcholine Receptor ë±5 http://flybase.net/reports/FBgn0028875.html "FBgn0028874, FBgn0066016" protein_coding_gene "0042166=acetylcholine binding, 0004889=acetylcholine-activated cation-selective channel activity" 0006812=cation transport "0045211=postsynaptic membrane, 0016021=integral component of membrane, 0005892=acetylcholine-gated channel complex" "nAcRalpha-34e, CT14633, BG:DS05899.5, daf, lincRNA.S1055, BG:DS05899.4, CG32975, nAChRalpha-34E, nAcRalpha-34E, lincRNA.128, Nic 34E, anon-WO02059370.44, nicotinic Acetylcholine Receptor_34E, Dalpha5, CG16878, nAChR, CG4498, nAChRalpha5, nicotinic Acetylcholine Receptor alpha 34E" "IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR002394=Nicotinic acetylcholine receptor, IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR018000=Neurotransmitter-gated ion-channel, conserved site" CG32975 16-Dec-15 2015_12 "ENSDARG00000037427(si:ch211-39a7.1),ENSDARG00000035785(chrna7),ENSDARG00000037424,ENSDARG00000033954" WBGene00000055(acr-16) "ENSXETG00000016395(),ENSXETG00000018003()" ENSMUSG00000030525(Chrna7) "ENSG00000175344(CHRNA7),ENSG00000166664(CHRFAM7A)" "lethal,viable" FBgn0022224 ubl ubiquitin like http://flybase.net/reports/FBgn0022224.html FBgn0033105 protein_coding_gene 0022008=neurogenesis 0005737=cytoplasm "l(2)k03203, dubl, Drosophila ubiquitin like, mut182, lethal (2) k03203, CG3450" "IPR029071=Ubiquitin-related domain, IPR000626=Ubiquitin domain" CG3450 16-Dec-15 2015_12 YNR032C-A(HUB1) WBGene00006726(ubl-5) ENSXETG00000026973(BC077708.1) "ENSMUSG00000078368(Gm2001),ENSMUSG00000072910(Gm16381)" ENSG00000198258(UBL5) "lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000039 nAChRë±2 nicotinic Acetylcholine Receptor ë±2 http://flybase.net/reports/FBgn0000039.html protein_coding_gene "0004889=acetylcholine-activated cation-selective channel activity, 0015464=acetylcholine receptor activity" "0007271=synaptic transmission, cholinergic, 0006812=cation transport" "0005887=integral component of plasma membrane, 0045211=postsynaptic membrane, 0005892=acetylcholine-gated channel complex" "Acr96Ab, SAD, da2, Dalpha2 nicotimic acetylcholine receptor, sad, nAChRa2, AcrE, Da2, alpha2, nicotinic Acetylcholine Receptor alpha 96Ab, nicotinic acetylcholine receptor alpha subunit gene at 96AB, nAcRalpha-96Ab, alpha[[2]], CG6844, Second alpha-like subunit of Drosophila, Dalpha2/SAD, D[a2], Dalpha, Dmalpha2, CG6844-PA, nAchRalpha-96Ab, nAcRs, Dalpha2, nAChR, nAcr96Ab, nicotinic acetylcholine receptor alpha-2, Drosophila alpha-like subunit 2, nAChR Dalpha2, nAChRalpha-96A" "IPR027361=Nicotinic acetylcholine-gated receptor, transmembrane domain, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006201=Neurotransmitter-gated ion-channel, IPR018000=Neurotransmitter-gated ion-channel, conserved site, IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR002394=Nicotinic acetylcholine receptor" CG6844 16-Dec-15 2015_12 "ENSDARG00000057025(chrna2b),ENSDARG00000006602(chrna2a),ENSDARG00000058393(chrna4),ENSDARG00000070724(LOC563696),ENSDARG00000057848,ENSDARG00000054497(LOC568467),ENSDARG00000055559(chrna6)" WBGene00006774(unc-38) ENSXETG00000017553(CHRNA2) "ENSMUSG00000032303(Chrna3),ENSMUSG00000031491(Chrna6),ENSMUSG00000027577(Chrna4),ENSMUSG00000022041(Chrna2)" "ENSG00000101204(CHRNA4),ENSG00000120903(CHRNA2),ENSG00000080644(CHRNA3),ENSG00000147434(CHRNA6)" " pupal stage , embryonic stage , embryonic stage | late " " embryonic central nervous system

, supraesophageal ganglion

, subesophageal ganglion

" viable DRSC24487 K 0.593513777 -0.009670847 0.269153657 0.678002676 1.812787424 1.136295682 FBgn0030692 mRpS30 mitochondrial ribosomal protein S30 http://flybase.net/reports/FBgn0030692.html protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation "0005875=microtubule associated complex, 0005763=mitochondrial small ribosomal subunit" "MRP-S30, CG8470, mRSp30" IPR010793=Ribosomal protein L37/S30 CG8470 16-Dec-15 2015_12 WBGene00044321(tag-264) ENSMUSG00000021731(Mrps30) ENSG00000112996(MRPS30) "viable,visible" trichogen cell FBgn0086450 su(r) suppressor of rudimentary http://flybase.net/reports/FBgn0086450.html "FBgn0003574, FBgn0016718" protein_coding_gene "0017113=dihydropyrimidine dehydrogenase (NADP+) activity, 0051536=iron-sulfur cluster binding, 0004152=dihydroorotate dehydrogenase activity, 0004159=dihydrouracil dehydrogenase (NAD+) activity" "0055114=oxidation-reduction process, 0006207='de novo' pyrimidine nucleobase biosynthetic process" 0005737=cytoplasm "CG2194, pyd1, Pyd1, Dreg-3, Reg-3, Rhythmically expressed gene 3, Drosophila Rhythmically expressed gene 3" "IPR013785=Aldolase-type TIM barrel, IPR017900=4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR001295=Dihydroorotate dehydrogenase, conserved site, IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR005720=Dihydroorotate dehydrogenase domain, IPR009051=Alpha-helical ferredoxin, IPR017896=4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR028261=Dihydroprymidine dehydrogenase domain II" CG2194 16-Dec-15 2015_12 ENSDARG00000010267(dpyd) WBGene00016103(dpyd-1) ENSXETG00000008600() ENSMUSG00000033308(Dpyd) ENSG00000188641(DPYD) " embryonic stage | late , adult stage " adult head

FBgn0051326 CG31326 http://flybase.net/reports/FBgn0051326.html FBgn0038212 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "cg9645, CG9645, SPH144" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG31326 16-Dec-15 2015_12 "ENSDARG00000068726(LOC100002060),ENSDARG00000007988(masp2)" "ENSMUSG00000027249(F2),ENSMUSG00000031444(F10),ENSMUSG00000059481(Plg),ENSMUSG00000024386(Proc),ENSMUSG00000031138(F9),ENSMUSG00000031443(F7)" "viable,fertile" FBgn0029896 CG3168 http://flybase.net/reports/FBgn0029896.html FBgn0046238 protein_coding_gene 0022857=transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane "LP06294.5prime, BEST:LP06294" "IPR011701=Major facilitator superfamily, IPR005828=Major facilitator, sugar transporter-like, IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site" CG3168 16-Dec-15 2015_12 ENSDARG00000063456(LOC570651) "YNL065W(AQR1),YIL121W(QDR2),YIL120W(QDR1),YBR043C(QDR3),YBR180W(DTR1)" ENSXETG00000007626(SV2B) "ENSMUSG00000051111(Sv2c),ENSMUSG00000038486(Sv2a),ENSMUSG00000053025(Sv2b)" "ENSG00000122012(SV2C),ENSG00000159164(SV2A),ENSG00000185518(SV2B)" FBgn0086758 chinmo Chronologically inappropriate morphogenesis http://flybase.net/reports/FBgn0086758.html "FBgn0082597, FBgn0010566, FBgn0051666, FBgn0031353, FBgn0031354, FBgn0031355" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0016319=mushroom body development, 0048813=dendrite morphogenesis, 0007476=imaginal disc-derived wing morphogenesis" "CG17156, F, Chinmo, CG10871, CG31666, chronologically inappropriate morphogenesis, chronologically -inappropriate morphogenesis, unnamed, l(2)04111, CG17649, lethal (2) 04111" "IPR000210=BTB/POZ domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR011333=POZ domain" CG31666 16-Dec-15 2015_12 ENSMUSG00000046962(Zfp295) DRSC00509 IE -0.441653025 -3.462468428 -2.009506417 -1.771552176 0.486261561 -0.028031968 FBgn0027107 Inx6 Innexin 6 http://flybase.net/reports/FBgn0027107.html protein_coding_gene 0005243=gap junction channel activity "0010496=intercellular transport, 0072375=medium-term memory" "0005921=gap junction, 0016021=integral component of membrane" "inx-6, inx6, Dm-inx6, CG17063, FBpp0077031, pas related protein 6, innexin 6, prp6" IPR000990=Innexin CG17063 16-Dec-15 2015_12 "WBGene00002123(inx-1),WBGene00002135(inx-13),WBGene00006747(unc-7),WBGene00006749(unc-9),WBGene00002140(inx-18),WBGene00002126(inx-4),WBGene00002125(inx-3),WBGene00002127(inx-5),WBGene00002141(inx-19),WBGene00001136(eat-5),WBGene00002133(inx-11),WBGene00002138(inx-16),WBGene00002132(inx-10),WBGene00002142(inx-20),WBGene00002134(inx-12),WBGene00002139(inx-17),WBGene00002124(inx-2),WBGene00002129(inx-7),WBGene00002137(inx-15),WBGene00002128(inx-6),WBGene00002131(inx-9),WBGene00002130(inx-8)" "memory defective,heat sensitive,viable" FBgn0040512 ë¦COP Coat Protein (coatomer) ë¦ http://flybase.net/reports/FBgn0040512.html FBgn0036651 protein_coding_gene "0016491=oxidoreductase activity, 0005215=transporter activity, 0005198=structural molecule activity" "0055114=oxidation-reduction process, 0006909=phagocytosis, 0010883=regulation of lipid storage, 0006890=retrograde vesicle-mediated transport, Golgi to ER" 0030126=COPI vesicle coat "CG3948, copz1, zetacop, zetaCOP, CT13124, COPI zeta subunit, zetaCop, zeta-Cop" "IPR008333=Oxidoreductase, FAD-binding domain, IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR011012=Longin-like domain, IPR017938=Riboflavin synthase-like beta-barrel, IPR001834=NADH:cytochrome b5 reductase (CBR), IPR001709=Flavoprotein pyridine nucleotide cytochrome reductase, IPR022775=AP complex, mu/sigma subunit, IPR001433=Oxidoreductase FAD/NAD(P)-binding" CG3948 16-Dec-15 2015_12 "ENSDARG00000017844(copz1),ENSDARG00000006786(copz2)" YPL010W(RET3) WBGene00010333(F59E10.3) ENSXETG00000027403(copz1) "ENSMUSG00000060992(Copz1),ENSMUSG00000018672(Copz2)" "ENSG00000111481(COPZ1),ENSG00000005243(COPZ2)" lethal DRSC11412 E -0.30202269 0.637253278 2.522808671 -4.135443287 0.046721315 0.963775547 FBgn0035355 CG16985 http://flybase.net/reports/FBgn0035355.html FBgn0047125 protein_coding_gene 0047617=acyl-CoA hydrolase activity 0051289=protein homotetramerization BcDNA:RE30174 "IPR029069=HotDog domain, IPR003736=Phenylacetic acid degradation-related domain, IPR006683=Thioesterase superfamily" CG16985 16-Dec-15 2015_12 ENSDARG00000061728(acot13) WBGene00018370(F42H10.6) ENSXETG00000025940(Q6DER5_XENTR) ENSMUSG00000006717(Acot13) ENSG00000112304(ACOT13) "viable,fertile" DRSC08501 K -0.335192919 -0.611143794 1.197770216 0.127917449 1.54774979 1.49007604 FBgn0050438 CG30438 http://flybase.net/reports/FBgn0050438.html "FBgn0047093, FBgn0047220" protein_coding_gene "0016758=transferase activity, transferring hexosyl groups" 0008152=metabolic process "dGlcAT-BSII, BcDNA:RE54684, GlcAT-P, BcDNA:LD09936" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG30438 16-Dec-15 2015_12 "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000010570(),ENSXETG00000021896(UGT8),ENSXETG00000009055(),ENSXETG00000006085(),ENSXETG00000006082()" ENSG00000174607(UGT8) viable DRSC21419 E 0.814151657 -1.416216034 -0.605995534 -1.593239149 0.361836296 1.138546583 FBgn0027657 glob1 globin 1 http://flybase.net/reports/FBgn0027657.html protein_coding_gene "0019825=oxygen binding, 0020037=heme binding, 0005506=iron ion binding" 0015671=oxygen transport 0005737=cytoplasm "globin, Glob1, DmeGb1, dmeglob1, Hb, DmHb1, Hemoglobin, globin1, CG9734, Globin 1, hemoglobin gene 1, DmeGlob1, DmHb" "IPR009050=Globin-like, IPR012292=Globin/Protoglobin, IPR000971=Globin" CG9734 16-Dec-15 2015_12 "ENSDARG00000070148(cygb2),ENSDARG00000052289,ENSDARG00000038260(cygb1),ENSDARG00000069750,ENSDARG00000069749,ENSDARG00000069741,ENSDARG00000069746,ENSDARG00000069734(zgc:92880),ENSDARG00000032896(xgb),ENSDARG00000069735(si:ch211-5k11.6),ENSDARG00000045144(zgc:163057)" "ENSMUSG00000020810(Cygb),ENSMUSG00000018893(Mb),ENSMUSG00000055609(Hba-x),ENSMUSG00000052187(Hbb-y),ENSMUSG00000052217(Hbb-bh1)" "ENSG00000161544(CYGB),ENSG00000130656(HBZ),ENSG00000206178,ENSG00000198125(MB),ENSG00000213931(HBE1),ENSG00000196565(HBG2),ENSG00000221842,ENSG00000213934(HBG1),ENSG00000206172(HBA1),ENSG00000188536(HBA2),ENSG00000188170,ENSG00000086506(HBQ1)" viable FBgn0039671 CG11470 http://flybase.net/reports/FBgn0039671.html protein_coding_gene IPR007931=Protein of unknown function DUF725 CG11470 16-Dec-15 2015_12 viable DRSC14313 K -0.342770977 -0.610995523 0.422935057 0.092421448 1.9276504 0.05829375 FBgn0033846 mip120 Myb-interacting protein 120 http://flybase.net/reports/FBgn0033846.html protein_coding_gene "0003677=DNA binding, 0005515=protein binding" "0008340=determination of adult lifespan, 0048477=oogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0030317=sperm motility, 0007307=eggshell chorion gene amplification" "0031523=Myb complex, 0000785=chromatin, 0005700=polytene chromosome" "CG6061, l(3)L4569, MIP120, Mip120, p120" "IPR005172=CRC domain, IPR028307=Lin-54 family" CG6061 16-Dec-15 2015_12 ENSDARG00000063194(lin54) ENSXETG00000000369(LIN54) ENSMUSG00000035310(Lin54) ENSG00000189308(LIN54) "viable,reduced,visible,female sterile,recessive,male sterile,lethal,neuroanatomy defective" "eye,egg chamber,nucleus & nurse cell,nucleus & follicle cell,spermatozoon,neurite | pharate adult stage" DRSC06960 IE 2.308713766 -0.745895076 1.781550961 -2.088495671 1.010031817 -0.191092685 FBgn0053193 sav salvador http://flybase.net/reports/FBgn0053193.html "FBgn0026180, FBgn0039046, FBgn0039047, FBgn0046446" protein_coding_gene "0005515=protein binding, 0032947=protein complex scaffold" "0035329=hippo signaling, 0045570=regulation of imaginal disc growth, 0072002=Malpighian tubule development, 0042127=regulation of cell proliferation, 0040014=regulation of multicellular organism growth, 0046666=retinal cell programmed cell death, 0008285=negative regulation of cell proliferation, 0048863=stem cell differentiation, 0007444=imaginal disc development, 0045464=R8 cell fate specification, 0043065=positive regulation of apoptotic process, 0072089=stem cell proliferation, 0010212=response to ionizing radiation, 0046621=negative regulation of organ growth, 0048814=regulation of dendrite morphogenesis" "0005912=adherens junction, 0005737=cytoplasm" "Salvador/Shar-pei, shar-pei, CG13831, Sav, Salvador, CG13832, CG33193, salvador/shar-pei, anon-WO0172774.152" "IPR030030=Scaffold protein salvador, IPR011524=SARAH domain, IPR001202=WW domain" CG33193 16-Dec-15 2015_12 ENSDARG00000006196(sav1) WBGene00020427(sav-1) ENSXETG00000027740(sav1) ENSMUSG00000021067(Sav1) ENSG00000151748(SAV1) "visible,somatic clone,lethal,increased cell number,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,progressive,stress response defective,cell polarity defective,large body,size defective,small body,partially lethal - majority die,body color defective" "eye,somatic clone,pigment cell,ectopic,interommatidial bristle,supernumerary,cell cycle | somatic clone,haltere,mesothoracic tergum,eye photoreceptor cell,eye disc,progressive,autophagic vacuole | progressive | somatic clone,dorsal multidendritic neuron ddaC | somatic clone & dendritic tree,adult Malpighian tubule,adult head,cell autonomous,ommatidial precursor cluster,photoreceptor cell R8 of yellow ommatidium,photoreceptor cell R8 of pale ommatidium,wing,posterior,adult thorax,wing disc,chaeta,trichogen cell" FBgn0036809 CG12477 http://flybase.net/reports/FBgn0036809.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0000209=protein polyubiquitination "IPR001841=Zinc finger, RING-type, IPR000571=Zinc finger, CCCH-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site" CG12477 16-Dec-15 2015_12 "sleep defective,female limited,viable" FBgn0002782 moo moorish http://flybase.net/reports/FBgn0002782.html gene mo 16-Dec-15 2015_12 "partially lethal - majority die,recessive,body color defective" FBgn0015873 anon-48Ab anon-48Ab http://flybase.net/reports/FBgn0015873.html gene "II, transcript group II" 16-Dec-15 2015_12 FBgn0001657 l(1)ds11 lethal (1) discs small 11 http://flybase.net/reports/FBgn0001657.html gene l(1)1-43 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0037156 CG11523 http://flybase.net/reports/FBgn0037156.html protein_coding_gene "IPR023231=GSKIP domain, IPR007967=Protein of unknown function DUF727" CG11523 16-Dec-15 2015_12 ENSDARG00000038099(zgc:55683) "WBGene00020782(T24H7.3),WBGene00007357(C06A12.3)" ENSG00000100744(C14orf129) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0034365 CG5335 http://flybase.net/reports/FBgn0034365.html protein_coding_gene 0030246=carbohydrate binding "IPR001079=Galectin, carbohydrate recognition domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG5335 16-Dec-15 2015_12 "WBGene00002264(lec-1),WBGene00002266(lec-3),WBGene00002267(lec-4),WBGene00002268(lec-5),WBGene00008284(C53D6.7)" viable FBgn0000254 Cbp82F Calmodulin-binding protein 82F http://flybase.net/reports/FBgn0000254.html gene 0005516=calmodulin binding Cal82F 16-Dec-15 2015_12 adult stage adult head

FBgn0004791 ray rayon http://flybase.net/reports/FBgn0004791.html gene 0007304=chorion-containing eggshell formation 16-Dec-15 2015_12 female sterile FBgn0004154 l(2)51Da lethal (2) 51Da http://flybase.net/reports/FBgn0004154.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" FBgn0029034 l(2)Q39 lethal (2) Q39 http://flybase.net/reports/FBgn0029034.html gene Q39 16-Dec-15 2015_12 "lethal,recessive" FBgn0260660 Mp Multiplexin http://flybase.net/reports/FBgn0260660.html "FBgn0035731, FBgn0035732, FBgn0053171, FBgn0035729" protein_coding_gene "0005198=structural molecule activity, 0030246=carbohydrate binding" "0007155=cell adhesion, 0071711=basement membrane organization, 0007005=mitochondrion organization, 0014732=skeletal muscle atrophy, 2001046=positive regulation of integrin-mediated signaling pathway, 0008045=motor neuron axon guidance, 0014899=cardiac muscle atrophy" "0031012=extracellular matrix, 0005581=collagen trimer" "CG33171, CG14822, CG42543, CG8647, Collagen-like, Multiplexin, multiplexin, dmp, COL18A1, CT14872, CG8645, mp, Dmp" "IPR008160=Collagen triple helix repeat, IPR016187=C-type lectin fold, IPR010515=Collagenase NC10/endostatin, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001791=Laminin G domain, IPR016186=C-type lectin-like" CG42543 16-Dec-15 2015_12 "ENSDARG00000061848(LOC100333003),ENSDARG00000041746,ENSDARG00000036558(col18a1)" FBgn0053082 CG33082 http://flybase.net/reports/FBgn0053082.html protein_coding_gene "IPR007175=RNAse P, Rpr2/Rpp21 subunit" CG33082 16-Dec-15 2015_12 ENSDARG00000043404(rpp21) FBgn0030774 spheroide spheroide http://flybase.net/reports/FBgn0030774.html "FBgn0026293, FBgn0044725" protein_coding_gene 0004252=serine-type endopeptidase activity "0045087=innate immune response, 0050830=defense response to Gram-positive bacterium, 0045752=positive regulation of Toll signaling pathway, 0006508=proteolysis, 0050832=defense response to fungus" 0005576=extracellular region "CG9675, anon-WO0140519.154, anon-EST:ParkEST153, Spheroide, SPH114" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG9675 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" immune response defective FBgn0263120 Acsl Acyl-CoA synthetase long-chain http://flybase.net/reports/FBgn0263120.html "FBgn0010609, FBgn0022182, FBgn0033318, FBgn0046428, FBgn0065770" protein_coding_gene 0004467=long-chain fatty acid-CoA ligase activity "0007411=axon guidance, 0022008=neurogenesis, 0007268=synaptic transmission, 0007399=nervous system development, 0010890=positive regulation of sequestering of triglyceride, 0001676=long-chain fatty acid metabolic process, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0030514=negative regulation of BMP signaling pathway, 0061502=early endosome to recycling endosome transport, 0035282=segmentation" "0005783=endoplasmic reticulum, 0030424=axon, 0005737=cytoplasm, 0005811=lipid particle" "FCS, Fatty acyl CoA synthetase, Long-chain acyl-CoA synthetase, 7447, l(2)SH0465, lethal (2) SH0465, long-chain acyl-CoA synthetase, anon-WO0172774.173, l(2)k05304, l(2)SH2 0465, l(2)7447, dFAC, lethal (2) 44DEa, CG8732, fatty acyl coenzyme A (CoA) synthetase, fatty acyl-CoA synthetase, FACS, l(2)05847, dAcsl, Fatty acyl-CoA synthetase, l(2)44DEa" "IPR025110=AMP-binding enzyme C-terminal domain, IPR000873=AMP-dependent synthetase/ligase, IPR020845=AMP-binding, conserved site" CG8732 16-Dec-15 2015_12 "ENSDARG00000014674(acsl3b),ENSDARG00000032079(acsl3a),ENSDARG00000004078(acsl4a),ENSDARG00000067954,ENSDARG00000010752(acsl4l)" "YMR246W(FAA4),YIL009W(FAA3),YOR317W(FAA1)" "WBGene00018152(acs-4),WBGene00016716(acs-17)" ENSXETG00000012429(ACSL4) "ENSMUSG00000032883(Acsl3),ENSMUSG00000031278(Acsl4)" "ENSG00000123983(ACSL3),ENSG00000068366(ACSL4)" DRSC07252 I 1.596669266 0.039032602 0.392512877 -1.006107434 -0.124193614 -0.630966628 FBgn0034160 CG5550 http://flybase.net/reports/FBgn0034160.html protein_coding_gene 0005578=proteinaceous extracellular matrix "Fibrinogen-like, FBpp0086184, Fibrinogen-related protein, AAL48972, AAF57948" "IPR014715=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR014716=Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837=Fibrinogen, conserved site, IPR002181=Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain" CG5550 16-Dec-15 2015_12 ENSDARG00000055478 WBGene00020516(T15B7.1) "ENSXETG00000006277(),ENSXETG00000024468(),ENSXETG00000024469(),ENSXETG00000024470(),ENSXETG00000000396(BC089673.1),ENSXETG00000024910(BC075449.1),ENSXETG00000008638(fcn1),ENSXETG00000001807(),ENSXETG00000007176(BC090364.1)" "ENSMUSG00000026841(Fibcd1),ENSMUSG00000026938(Fcna),ENSMUSG00000026835(Fcnb)" "ENSG00000160339(FCN2),ENSG00000142748(FCN3),ENSG00000085265(FCN1),ENSG00000166482(MFAP4)" viable FBgn0031534 Snx1 Sorting nexin 1 http://flybase.net/reports/FBgn0031534.html protein_coding_gene "0008565=protein transporter activity, 0032266=phosphatidylinositol-3-phosphate binding" "0061357=positive regulation of Wnt protein secretion, 0042147=retrograde transport, endosome to Golgi, 0006886=intracellular protein transport" "0005768=endosome, 0030905=retromer complex, outer shell" "Dsnx1, Vps5, CG2774" "IPR001683=Phox homologous domain, IPR015404=Sorting nexin Vps5-like, C-terminal" CG2774 16-Dec-15 2015_12 "ENSDARG00000071031(snx1),ENSDARG00000053356(snx2)" YOR069W(VPS5) WBGene00004927(snx-1) "ENSXETG00000010653(snx1),ENSXETG00000004677(SNX2)" "ENSMUSG00000034484(Snx2),ENSMUSG00000032382(Snx1)" "ENSG00000205302(SNX2),ENSG00000028528(SNX1)" "viable,fertile" FBgn0032683 kon kon-tiki http://flybase.net/reports/FBgn0032683.html protein_coding_gene 0005515=protein binding "0007517=muscle organ development, 0045214=sarcomere organization, 0051491=positive regulation of filopodium assembly, 0030239=myofibril assembly, 0022008=neurogenesis, 0016203=muscle attachment, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development" "0051286=cell tip, 0005927=muscle tendon junction, 0043034=costamere, 0030018=Z disc" "CG10275, perd, perdido, NG2-like, CT28869, Kon" "IPR001791=Laminin G domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG10275 16-Dec-15 2015_12 "ENSDARG00000062402(frem1b),ENSDARG00000069473" ENSXETG00000015273() ENSMUSG00000032911(Cspg4) ENSG00000173546(CSPG4) "visible,lethal,viable,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic somatic muscle,filopodium | ectopicMef2.PR,wing,ventral longitudinal muscle,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval somatic muscle,segment border muscle,epithelium,female germline cyst" FBgn0034748 CG17807 http://flybase.net/reports/FBgn0034748.html protein_coding_gene "0008168=methyltransferase activity, 0016706=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 0055114=oxidation-reduction process "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR013216=Methyltransferase type 11, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR027450=Alpha-ketoglutarate-dependent dioxygenase AlkB-like" CG17807 16-Dec-15 2015_12 ENSDARG00000060256(LOC556362) WBGene00007581(C14B1.10) ENSXETG00000014487(TEgg091o15.1) ENSMUSG00000025899(Alkbh8) ENSG00000137760(ALKBH8) viable heart primordium FBgn0027602 CG8611 http://flybase.net/reports/FBgn0027602.html protein_coding_gene "0005524=ATP binding, 0004004=ATP-dependent RNA helicase activity, 0003676=nucleic acid binding" "cg8611, BcDNA:GH02833, DmRH11" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR011545=DEAD/DEAH box helicase domain, IPR025313=Domain of unknown function DUF4217, IPR001650=Helicase, C-terminal" CG8611 16-Dec-15 2015_12 ENSDARG00000035507(si:ch211-89p1.3) YKR024C(DBP7) ENSXETG00000006258(DDX31) ENSMUSG00000026806(Ddx31) ENSG00000125485(DDX31) viable FBgn0001125 Got2 Glutamate oxaloacetate transaminase 2 http://flybase.net/reports/FBgn0001125.html FBgn0031380 protein_coding_gene "0030170=pyridoxal phosphate binding, 0004069=L-aspartate:2-oxoglutarate aminotransferase activity" "0007416=synapse assembly, 0006531=aspartate metabolic process, 0006537=glutamate biosynthetic process, 0045213=neurotransmitter receptor metabolic process" "0005759=mitochondrial matrix, 0005739=mitochondrion, 0005811=lipid particle" "Got, Got-2, CG4233, Got 2, got2, GLUTAMATE OXALOACETATE TRANSAMINASE 2, mitochondrial aspartate aminotransferase, 152801_at" "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424=Pyridoxal phosphate-dependent transferase, IPR004838=Aminotransferases, class-I, pyridoxal-phosphate-binding site, IPR000796=Aspartate/other aminotransferase, IPR004839=Aminotransferase, class I/classII" CG4233 16-Dec-15 2015_12 "ENSDARG00000005840(LOC100329521),ENSDARG00000041068(got2a)" "WBGene00015778(C14F11.1),WBGene00016652(C44E4.3)" ENSXETG00000015896(got2) ENSMUSG00000031672(Got2) ENSG00000125166(GOT2) "viable,electrophoretic variant,neurophysiology defective,fertile" larval neuromuscular junction & postsynaptic membrane DRSC00643 K -0.255834431 0.275376617 0.283950443 0.444125638 1.596885102 0.66705571 FBgn0042712 HBS1 HBS1 http://flybase.net/reports/FBgn0042712.html FBgn0035284 protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding, 0003747=translation release factor activity" "0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0006415=translational termination" 0005829=cytosol "CG1898, Hbs1, hbs1" "IPR015033=HBS1-like protein, N-terminal, IPR000795=Transcription factor, GTP-binding domain, IPR009000=Translation protein, beta-barrel domain, IPR004161=Translation elongation factor EFTu/EF1A, domain 2, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR009001=Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR004160=Translation elongation factor EFTu/EF1A, C-terminal" CG1898 16-Dec-15 2015_12 ENSDARG00000036778(hbs1l) WBGene00010622(K07A12.4) ENSXETG00000003726(HBS1L) ENSMUSG00000019977(Hbs1l) ENSG00000112339(HBS1L) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC08544 IE 0.394461906 -1.782525663 -1.82912055 0.462734984 0.122304821 -0.618682845 FBgn0013303 Nca Neurocalcin http://flybase.net/reports/FBgn0013303.html FBgn0013306 protein_coding_gene 0005509=calcium ion binding 0042326=negative regulation of phosphorylation "CG7641, Ncalc, neurocalcin, nca" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR028846=Recoverin family" CG7641 16-Dec-15 2015_12 "ENSDARG00000018397(hpca),ENSDARG00000022763(zgc:63695),ENSDARG00000070688(ncalda),ENSDARG00000035884" "ENSXETG00000003521(hpcal1),ENSXETG00000001001(hpca),ENSXETG00000006631(NCALD)" "ENSMUSG00000051359(Ncald),ENSMUSG00000071379(Hpcal1)" "ENSG00000115756(HPCAL1),ENSG00000121905(HPCA)" FBgn0001248 Idh Isocitrate dehydrogenase http://flybase.net/reports/FBgn0001248.html "FBgn0013617, FBgn0035881" protein_coding_gene "0051287=NAD binding, 0004450=isocitrate dehydrogenase (NADP+) activity, 0000287=magnesium ion binding" "0006102=isocitrate metabolic process, 0006099=tricarboxylic acid cycle, 0001561=fatty acid alpha-oxidation, 0006097=glyoxylate cycle" "0005811=lipid particle, 0005739=mitochondrion, 0005777=peroxisome" "NADP-IDH, cIdh, CT22171, IDH, isocitrate dehydrogenase, Isocitrate dehydrogenase (NADP[+]), Idh-NADP, ICDH, CG7176, Isocitrate dehydrolase, idh, l(3)L3852, IDH-NADP, ISOCITRATE DEHYDROGENASE" "IPR004790=Isocitrate dehydrogenase NADP-dependent, IPR024084=Isopropylmalate dehydrogenase-like domain, IPR019818=Isocitrate/isopropylmalate dehydrogenase, conserved site" CG7176 16-Dec-15 2015_12 ENSDARG00000025375(idh1) "YDL066W(IDP1),YLR174W(IDP2),YNL009W(IDP3)" WBGene00010317(idh-1) ENSXETG00000008032(Q6GL17_XENTR) ENSMUSG00000025950(Idh1) ENSG00000138413(IDH1) "lethal,recessive,viable,fertile,electrophoretic variant,visible" trichogen cell DRSC10779 K 1.223779142 -0.336173402 -0.027874849 0.141519918 0.549240438 1.578174883 FBgn0035488 CG11593 http://flybase.net/reports/FBgn0035488.html FBgn0027676 protein_coding_gene anon-EST:Posey64 "IPR022181=Bcl2-/adenovirus E1B 19kDa-interacting protein 2, IPR001251=CRAL-TRIO lipid binding domain" CG11593 16-Dec-15 2015_12 "ENSDARG00000059423(si:dkey-267i17.5),ENSDARG00000071678,ENSDARG00000071682,ENSDARG00000013397(bnip2),ENSDARG00000059781(LOC100329872),ENSDARG00000060435(bnipl)" "ENSMUSG00000011958(Bnip2),ENSMUSG00000034958(Atcay),ENSMUSG00000028115(Bnipl)" "ENSG00000167654(ATCAY),ENSG00000140299(BNIP2),ENSG00000163141(BNIPL)" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038723 CG6195 http://flybase.net/reports/FBgn0038723.html FBgn0046292 protein_coding_gene 0005525=GTP binding BEST:GH15838 "IPR004095=TGS, IPR006073=GTP binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR031167=OBG-type guanine nucleotide-binding (G) domain, IPR005225=Small GTP-binding protein domain, IPR012676=TGS-like, IPR006074=GTP1/OBG, conserved site" CG6195 16-Dec-15 2015_12 ENSDARG00000006642(drg2) YGR173W(RBG2) WBGene00015346(C02F5.3) ENSXETG00000004022(drg2) ENSMUSG00000020537(Drg2) ENSG00000108591(DRG2) FBgn0039135 CG13603 http://flybase.net/reports/FBgn0039135.html protein_coding_gene CG13603 16-Dec-15 2015_12 "ENSDARG00000013292(zgc:101058),ENSDARG00000016894,ENSDARG00000060977(zgc:153018)" ENSXETG00000008615(TMEM179) ENSMUSG00000054013(Tmem179) ENSG00000189203(TMEM179) viable FBgn0011016 SsRë_ Signal sequence receptor ë_ http://flybase.net/reports/FBgn0011016.html "FBgn0026009, FBgn0027883" protein_coding_gene 0005048=signal sequence binding 0006621=protein retention in ER lumen "0016021=integral component of membrane, 0005783=endoplasmic reticulum, 0005875=microtubule associated complex, 0005811=lipid particle, 0005786=signal recognition particle, endoplasmic reticulum targeting, 0012505=endomembrane system" "SsRbeta, l(3)s1939, BcDNA:LD10457, anon-EST:Liang-1.1, CG5474, BcDNA.LD10457, Signal sequence receptor beta, clone 1.1" IPR008856=Translocon-associated protein subunit beta CG5474 16-Dec-15 2015_12 ENSDARG00000005230(ssr2) WBGene00020216(trap-2) ENSXETG00000002966(ssr2) ENSMUSG00000041355(Ssr2) ENSG00000163479(SSR2) "lethal,recessive,viable,fertile" FBgn0052808 CG32808 http://flybase.net/reports/FBgn0052808.html FBgn0025385 protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis EG:80H7.1 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG32808 16-Dec-15 2015_12 "ENSMUSG00000030713(Klk7),ENSMUSG00000064023(Klk8),ENSMUSG00000054046(Klk13),ENSMUSG00000067616(Klk11),ENSMUSG00000074155(Klk5),ENSMUSG00000044737(Klk14),ENSMUSG00000044485(Klk1b11),ENSMUSG00000059042(Klk1b9),ENSMUSG00000044430(Klk12),ENSMUSG00000055193(Klk15),ENSMUSG00000050063(Klk6),ENSMUSG00000066515(Klk1b3),ENSMUSG00000063177(Klk1b27),ENSMUSG00000063133(Klk1b1),ENSMUSG00000063903(Klk1),ENSMUSG00000063713(Klk1b24),ENSMUSG00000066516(Klk1b21),ENSMUSG00000030693(Klk10),ENSMUSG00000053719(Klk1b26),ENSMUSG00000060177(Klk1b22),ENSMUSG00000066513(Klk1b4),ENSMUSG00000066512(Klk1b5),ENSMUSG00000063089(Klk1b8),ENSMUSG00000006948(Klk4),ENSMUSG00000047884(Klk9),ENSMUSG00000038968(Klk1b16)" "ENSG00000167759(KLK13),ENSG00000167757(KLK11),ENSG00000129455(KLK8),ENSG00000167755(KLK6),ENSG00000129437(KLK14),ENSG00000167754(KLK5),ENSG00000167751(KLK2),ENSG00000142515(KLK3),ENSG00000174562(KLK15),ENSG00000213022(KLK9),ENSG00000169035(KLK7),ENSG00000167748(KLK1),ENSG00000186474(KLK12),ENSG00000167749(KLK4),ENSG00000129451(KLK10)" FBgn0026061 Mipp1 Multiple inositol polyphosphate phosphatase 1 http://flybase.net/reports/FBgn0026061.html protein_coding_gene "0003993=acid phosphatase activity, 0034417=bisphosphoglycerate 3-phosphatase activity, 0004721=phosphoprotein phosphatase activity" 0016311=dephosphorylation "0005886=plasma membrane, 0070062=extracellular exosome" "mipp1, CG4123, CK2082" "IPR029033=Histidine phosphatase superfamily, IPR016274=Histidine acid phosphatase, eukaryotic, IPR000560=Histidine phosphatase superfamily, clade-2" CG4123 16-Dec-15 2015_12 ENSDARG00000057058(minpp1a) ENSG00000107789(MINPP1) "viable,fertile" FBgn0032643 GCS2ë_ Glucosidase 2 ë_ subunit http://flybase.net/reports/FBgn0032643.html protein_coding_gene "0004558=alpha-1,4-glucosidase activity" "0006491=N-glycan processing, 0046331=lateral inhibition" "0012505=endomembrane system, 0017177=glucosidase II complex" "GCS2beta, Glucosidase 2 beta subunit, CG6453, Q9VJD1_DROME" "IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR028146=Glucosidase II beta subunit, N-terminal, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR026874=Glucosidase 2 subunit beta, IPR009011=Mannose-6-phosphate receptor binding domain" CG6453 16-Dec-15 2015_12 ENSDARG00000004470(prkcsh) YDR221W(GTB1) WBGene00014249(ZK1307.8) ENSXETG00000016744(prkcsh) ENSMUSG00000003402(Prkcsh) ENSG00000130175(PRKCSH) "viable,visible" "chaeta,supernumerary,trichogen cell,wing" DRSC02960 E -0.944504667 0.935699426 0.505663451 1.597077309 0.845439419 0.278840255 FBgn0027563 CG9631 http://flybase.net/reports/FBgn0027563.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" 0006508=proteolysis "SP60, BcDNA:GH08420" "IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG9631 16-Dec-15 2015_12 "ENSDARG00000068726(LOC100002060),ENSDARG00000007988(masp2)" "ENSMUSG00000027249(F2),ENSMUSG00000031444(F10),ENSMUSG00000059481(Plg),ENSMUSG00000024386(Proc),ENSMUSG00000031138(F9),ENSMUSG00000031443(F7)" viable FBgn0051370 CG31370 http://flybase.net/reports/FBgn0051370.html FBgn0039320 protein_coding_gene CG13660 "IPR011009=Protein kinase-like domain, IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227" CG31370 16-Dec-15 2015_12 "WBGene00019164(H06H21.8),WBGene00017027(D1044.1)" "viable,fertile" FBgn0035229 CG7852 http://flybase.net/reports/FBgn0035229.html protein_coding_gene 0017112=Rab guanyl-nucleotide exchange factor activity 0032483=regulation of Rab protein signal transduction 0005794=Golgi apparatus "IPR005112=dDENN domain, IPR001194=DENN domain, IPR001024=PLAT/LH2 domain, IPR005113=uDENN domain, IPR004012=RUN domain" CG7852 16-Dec-15 2015_12 "ENSDARG00000017006(dennd5a),ENSDARG00000003789(dennd5b)" WBGene00016889(C52E12.4) ENSXETG00000004425(DENND5A) "ENSMUSG00000030313,ENSMUSG00000035901(Dennd5a)" "ENSG00000184014(DENND5A),ENSG00000170456(DENND5B)" viable FBgn0027575 GABA-B-R2 metabotropic GABA-B receptor subtype 2 http://flybase.net/reports/FBgn0027575.html "FBgn0046522, FBgn0046523" protein_coding_gene "0004965=G-protein coupled GABA receptor activity, 0046982=protein heterodimerization activity" "0042048=olfactory behavior, 0007186=G-protein coupled receptor signaling pathway, 0007194=negative regulation of adenylate cyclase activity, 0031631=negative regulation of synaptic vesicle fusion to presynaptic membrane, 0046676=negative regulation of insulin secretion, 0007214=gamma-aminobutyric acid signaling pathway, 0071260=cellular response to mechanical stimulus" "0016021=integral component of membrane, 0038039=G-protein coupled receptor heterodimeric complex, 0005887=integral component of plasma membrane" "GABA-[[B]]R2, CG6706, GABA[[B]]receptor2, GH07312, anon-WO0170980.58, GBR, GABA B R2, GABA[[B]]-R2, GABABR2, GB2, BcDNA:GH07312, D-GABA[[B]]R2, anon-WO0170980.59, metabotropic GABA[[B]] receptor 2, D-Gaba2, GABA[[B]]R2, GABA[[B]]- 2 receptor" "IPR017979=GPCR, family 3, conserved site, IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region, IPR002456=GPCR, family 3, gamma-aminobutyric acid receptor, type B1, IPR002455=GPCR, family 3, gamma-aminobutyric acid receptor, type B, IPR017978=GPCR, family 3, C-terminal" CG6706 16-Dec-15 2015_12 WBGene00022675(gbb-2) ENSXETG00000018917(GABBR2) ENSMUSG00000039809(Gabbr2) ENSG00000136928(GABBR2) "short lived,nutrition conditional,neurophysiology defective,courtship behavior defective,viable,circadian rhythm defective" FBgn0070048 3L-211-27 3L-211-27 http://flybase.net/reports/FBgn0070048.html gene 0007379=segment specification 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0002125 l(2)II032 lethal (2) II032 http://flybase.net/reports/FBgn0002125.html gene 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" embryonic head FBgn0028151 l(3)S044422 lethal (3) S044422 http://flybase.net/reports/FBgn0028151.html gene 0444/22 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0001393 l(1)2Ce lethal (1) 2Ce http://flybase.net/reports/FBgn0001393.html gene l(1)GF316 16-Dec-15 2015_12 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,polyphasic,lethal - all die before end of larval stage,some die during larval stage" FBgn0015585 Acp63F Accessory gland protein 63F http://flybase.net/reports/FBgn0015585.html protein_coding_gene 0032504=multicellular organism reproduction 0005615=extracellular space "Acp63F/64A, CG10852, acp63F, Accessory gland protein 63F, Accessory gland peptide 63F, Acp63f, Acp63" CG10852 16-Dec-15 2015_12 adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0013433 beat-Ia beaten path Ia http://flybase.net/reports/FBgn0013433.html FBgn0024596 protein_coding_gene "0008045=motor neuron axon guidance, 0016198=axon choice point recognition, 0001746=Bolwig's organ morphogenesis, 0007411=axon guidance, 0007415=defasciculation of motor neuron axon" 0005576=extracellular region "triclops, Beaten path Ia, CCT, CG4846, beat, beat Ia, CT15567, Chaperonin containing TCP-1, BG:DS00913.3, Cct, Beat-Ia, Beaten Path Ia, Beat Ia, l(2)35Eb, l(2)35Ea, tric, beat1a, TRiC, beaten path, l(2)br48, l(2)br47" "IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain" CG4846 16-Dec-15 2015_12 " embryonic stage | stage 12-17 , embryonic stage " " motor neuron

, RP1 neuron

, RP3 neuron

, embryonic central nervous system | presumptive | restricted

, aCC neuron

" embryonic stage "viable,fertile,lethal,recessive" "Bolwig organ,photoreceptor,intersegmental nerve,segmental nerve,abdominal intersegmental nerve,motor neuron,abdominal segmental nerve,A1-7 dorsal acute muscle 1,A1-7 dorsal acute muscle 2,A1-7 dorsal oblique muscle 1,A1-7 dorsal oblique muscle 2,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,distal" FBgn0259532 B0731 http://flybase.net/reports/FBgn0259532.html gene 16-Dec-15 2015_12 visible "leg,tarsal segment,arista" FBgn0015462 l(2)37Cn lethal (2) 37Cn http://flybase.net/reports/FBgn0015462.html FBgn0013294 gene l(2)E68 16-Dec-15 2015_12 "visible,dominant,lethal,recessive" macrochaeta FBgn0017372 l(2)C19 lethal (2) C19 http://flybase.net/reports/FBgn0017372.html gene C19 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0039259 CG11781 http://flybase.net/reports/FBgn0039259.html FBgn0063030 protein_coding_gene "0012505=endomembrane system, 0072546=ER membrane protein complex" BcDNA:RE35789 "IPR008504=ER membrane protein complex subunit 6, IPR029008=Rab5-interacting protein family" CG11781 16-Dec-15 2015_12 ENSDARG00000035282(tmem93) WBGene00017999(F33D4.7) "ENSXETG00000026014(TEgg053k02.1),ENSXETG00000025570()" ENSMUSG00000047260(Tmem93) ENSG00000127774(TMEM93) "viable,partially lethal - majority die,some die during pupal stage" FBgn0002967 nrd neural disrupted http://flybase.net/reports/FBgn0002967.html gene "0007390=germ-band shortening, 0008258=head involution, 0007399=nervous system development" "lethal(2)23Aa, l(2)23Aa" 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive" "embryonic brain,ventral nerve cord,extended germ band embryo,dorsal closure embryo,subesophageal ganglion,embryonic/first instar larval cuticle,embryonic ventral neuromere,cephalopharyngeal skeleton,presumptive embryonic/larval central nervous system,posterior,presumptive embryonic/larval peripheral nervous system" FBgn0028497 CG3530 http://flybase.net/reports/FBgn0028497.html FBgn0040661 protein_coding_gene "0046872=metal ion binding, 0008138=protein tyrosine/serine/threonine phosphatase activity, 0004725=protein tyrosine phosphatase activity" "0016311=dephosphorylation, 0000278=mitotic cell cycle, 0006470=protein dephosphorylation" "BcDNA:GH04637, MYOTUBULARIN-like, CG18093, BcDNA" "IPR000387=Tyrosine specific protein phosphatases domain, IPR017455=Zinc finger, FYVE-related, IPR030564=Myotubularin family, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR010569=Myotubularin-like phosphatase domain, IPR016130=Protein-tyrosine phosphatase, active site, IPR000306=FYVE zinc finger, IPR029021=Protein-tyrosine phosphatase-like, IPR011011=Zinc finger, FYVE/PHD-type" CG3530 16-Dec-15 2015_12 "ENSDARG00000016794(mtmr6),ENSDARG00000008592(mtmr8),ENSDARG00000037101(mtmr7a),ENSDARG00000070412(mtmr7b)" YJR110W(YMR1) WBGene00003478(mtm-6) "ENSXETG00000000690(MTMR7),ENSXETG00000010682(MTMR6)" "ENSMUSG00000021987(Mtmr6),ENSMUSG00000039431(Mtmr7)" "ENSG00000003987(MTMR7),ENSG00000139505(MTMR6),ENSG00000102043(MTMR8)" "viable,visible,planar polarity defective" "trichogen cell,mesothoracic tergum" FBgn0041182 Tep2 Thioester-containing protein 2 http://flybase.net/reports/FBgn0041182.html "FBgn0031931, FBgn0031932" protein_coding_gene "0030414=peptidase inhibitor activity, 0004866=endopeptidase inhibitor activity" "0019731=antibacterial humoral response, 0050829=defense response to Gram-negative bacterium, 0006909=phagocytosis" 0005615=extracellular space "Thioester containing protein II, T13, Thiolester containing protein II, CG7052, dTEPII, 145971_at, Tep2, TEP II, TEP2, TepII, Tep II, 145970_at, TEP, CG18589, Tep 2, TEP2mel, tepII" "IPR009048=Alpha-macroglobulin, receptor-binding, IPR008930=Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR011626=Alpha-macroglobulin complement component, IPR001599=Alpha-2-macroglobulin, IPR002890=Alpha-2-macroglobulin, N-terminal, IPR019742=Alpha-2-macroglobulin, conserved site, IPR011625=Alpha-2-macroglobulin, N-terminal 2, IPR019565=Alpha-2-macroglobulin, thiol-ester bond-forming" CG7052 16-Dec-15 2015_12 "ENSDARG00000056314(a2ml),ENSDARG00000041645(sb:cb37),ENSDARG00000041685(LOC100006782),ENSDARG00000056588,ENSDARG00000024892,ENSDARG00000017289,ENSDARG00000017619,ENSDARG00000041639,ENSDARG00000035291,ENSDARG00000053178,ENSDARG00000027924,ENSDARG00000035292,ENSDARG00000041653,ENSDARG00000058274,ENSDARG00000008835" WBGene00013969(ZK337.1) "ENSXETG00000024219(BC093458.1),ENSXETG00000024227(),ENSXETG00000017070(),ENSXETG00000006980(BC091705.1),ENSXETG00000006979(),ENSXETG00000009402(),ENSXETG00000017401(),ENSXETG00000009400()" ENSMUSG00000046186(Cd109) ENSG00000156535(CD109) viable FBgn0040259 Ugt86Da Ugt86Da http://flybase.net/reports/FBgn0040259.html "FBgn0027072, FBgn0037865" protein_coding_gene "0008194=UDP-glycosyltransferase activity, 0016758=transferase activity, transferring hexosyl groups" 0006011=UDP-glucose metabolic process 0012505=endomembrane system "AC 006491A, ugt86Da, CG18578, BEST:GM04645, GM04645" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG18578 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00010904(ugt-62),WBGene00018206(ugt-61)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0039705 Atg16 Autophagy-related 16 http://flybase.net/reports/FBgn0039705.html "FBgn0039706, FBgn0040624, FBgn0051033" protein_coding_gene 0019776=Atg8 ligase activity "0006914=autophagy, 1902350=cellular response to chloroquine, 0010506=regulation of autophagy, 0035096=larval midgut cell programmed cell death, 0016236=macroautophagy" 0034274=Atg12-Atg5-Atg16 complex "CG18683, CG31033, CG18040, CG15513, Autophagy-specific gene 16" "IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR013923=Autophagy-related protein 16, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG31033 16-Dec-15 2015_12 ENSDARG00000057430 "WBGene00019427(atg-16.2),WBGene00017178(atg-16.1)" ENSXETG00000013872(ATG16L1) ENSMUSG00000026289(Atg16l1) ENSG00000085978(ATG16L1) viable "embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0031818 CG9536 http://flybase.net/reports/FBgn0031818.html protein_coding_gene 0005515=protein binding 0006486=protein glycosylation 0005794=Golgi apparatus "IPR013861=Transmembrane protein DUF1751, eukaryotic" CG9536 16-Dec-15 2015_12 ENSDARG00000055763(tmem115) YOL107W() WBGene00008687(F11A10.6) ENSXETG00000000082(TMEM115) ENSMUSG00000010045(Tmem115) ENSG00000126062(TMEM115) "viable,fertile,female fertile" FBgn0025394 inc insomniac http://flybase.net/reports/FBgn0025394.html "FBgn0040897, FBgn0052810" protein_coding_gene "0042803=protein homodimerization activity, 0005216=ion channel activity, 0017022=myosin binding" "0051260=protein homooligomerization, 0045187=regulation of circadian sleep/wake cycle, sleep, 0006811=ion transport, 0030431=sleep" "CG14784, ins, EG:196F3.2, CG14783, CG32810" "IPR011333=POZ domain, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR000210=BTB/POZ domain" CG32810 16-Dec-15 2015_12 "ENSDARG00000015722(kctd5),ENSDARG00000025875(zgc:153278),ENSDARG00000056050(LOC568267)" WBGene00016871(tag-303) "ENSXETG00000004026(kctd5),ENSXETG00000012508(KCTD2)" "ENSMUSG00000016946(Kctd5),ENSMUSG00000016940(Kctd2),ENSMUSG00000033287(Kctd17)" "ENSG00000167977(KCTD5),ENSG00000180901(KCTD2),ENSG00000100379(KCTD17)" "sleep defective,recessive,short lived,viable,fertile,neuroanatomy defective,circadian rhythm defective,visible,RU486 conditional" "mushroom body alpha-lobe,mushroom body beta-lobe,trichogen cell" DRSC28898 K 0.666509793 0.464407973 0.319747784 -0.643275321 1.564706349 1.614933236 FBgn0030943 CG6540 http://flybase.net/reports/FBgn0030943.html protein_coding_gene 0005487=nucleocytoplasmic transporter activity "0006999=nuclear pore organization, 0055085=transmembrane transport, 0007476=imaginal disc-derived wing morphogenesis" "0044613=nuclear pore central transport channel, 0031965=nuclear membrane, 0005811=lipid particle" Nup35 "IPR017389=Nucleoporin, NUP53, IPR007846=RNA-recognition motif (RRM) Nup35-type domain" CG6540 16-Dec-15 2015_12 ENSDARG00000012222(zgc:65979) WBGene00003805(npp-19) ENSXETG00000001335(NUP35) ENSMUSG00000026999(Nup35) ENSG00000163002(NUP35) viable FBgn0053013 CR33013 http://flybase.net/reports/FBgn0053013.html "FBgn0033719, FBgn0050041" pseudogene_attribute "CG13161, CG33013, CG30041" CR33013 16-Dec-15 2015_12 YBR074W() ENSMUSG00000046324(Ermp1) ENSG00000099219(ERMP1) "viable,fertile" DRSC06286 K 0.047187026 -0.401063606 0.193932537 -0.042691498 1.728410997 0.740531105 FBgn0031909 CG5181 http://flybase.net/reports/FBgn0031909.html protein_coding_gene 0003697=single-stranded DNA binding 0006281=DNA repair "0005737=cytoplasm, 0005634=nucleus" "IPR012340=Nucleic acid-binding, OB-fold" CG5181 16-Dec-15 2015_12 "ENSDARG00000004692(obfc2a),ENSDARG00000043685(zgc:114087),ENSDARG00000070942" WBGene00015554(C06G3.8) ENSXETG00000024652(TGas103n10.1) "ENSMUSG00000025374(Obfc2b),ENSMUSG00000026107(Obfc2a)" "ENSG00000139579(OBFC2B),ENSG00000173559(OBFC2A)" "viable,fertile" FBgn0263112 Mitf Mitf http://flybase.net/reports/FBgn0263112.html "FBgn0067895, FBgn0040845, FBgn0069921" protein_coding_gene 0046983=protein dimerization activity "0001745=compound eye morphogenesis, 0006355=regulation of transcription, DNA-templated" "CG41130, dMitf, MITF, CG43369, CG40476, CG17469" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG43369 16-Dec-15 2015_12 "ENSDARG00000004729(tfe3a),ENSDARG00000019457(tfe3b),ENSDARG00000037833,ENSDARG00000003732(mitfa),ENSDARG00000010794(tfeb),ENSDARG00000008423(tfec)" WBGene00020930(hlh-30) "ENSXETG00000000154(MITF),ENSXETG00000019114(TFE3),ENSXETG00000011566(TFEC)" "ENSMUSG00000000134(Tcfe3),ENSMUSG00000035158(Mitf),ENSMUSG00000023990(Tcfeb)" "ENSG00000068323(TFE3),ENSG00000187098(MITF),ENSG00000112561(TFEB)" FBgn0040212 Dhap-at Dihydroxyacetone phosphate acyltransferase http://flybase.net/reports/FBgn0040212.html "FBgn0039340, FBgn0041212" protein_coding_gene "0004366=glycerol-3-phosphate O-acyltransferase activity, 0016287=glycerone-phosphate O-acyltransferase activity" 0008611=ether lipid biosynthetic process "0005778=peroxisomal membrane, 0005739=mitochondrion, 0005777=peroxisome" "Dihydroxyacetone phosphate acyltansferase, GPAT, DHAP-AT, glycerol-3-phosphate acyltransferase, Glycerol 3-phosphate acyltransferase, 8-1, glycerol-3-phosphate-acyltransferase, CG4625, Gpat" "IPR022284=Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase, IPR002123=Phospholipid/glycerol acyltransferase, IPR028353=Dihydroxyacetone phosphate acyltransferase" CG4625 16-Dec-15 2015_12 WBGene00012911(acl-7) ENSXETG00000022535(gnpat) ENSMUSG00000031985(Gnpat) ENSG00000116906(GNPAT) viable FBgn0042175 CG18858 http://flybase.net/reports/FBgn0042175.html protein_coding_gene 0008374=O-acyltransferase activity 0006629=lipid metabolic process 38C.53 "IPR029058=Alpha/Beta hydrolase fold, IPR003386=Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase" CG18858 16-Dec-15 2015_12 "ENSDARG00000010587,ENSDARG00000062375" WBGene00010872(M05B5.4) ENSXETG00000005810(PLA2G15) "ENSMUSG00000031903(Pla2g15),ENSMUSG00000035237(Lcat)" "ENSG00000103066(PLA2G15),ENSG00000213398(LCAT)" FBgn0260964 Vmat Vesicular monoamine transporter http://flybase.net/reports/FBgn0260964.html "FBgn0259816, FBgn0085016, FBgn0053528, FBgn0033849, FBgn0033852, FBtr0087689, FBpp0086808, FBtr0087690, FBpp0086809, FBtr0087691, FBpp0086810, FBtr0087692, FBpp0086811, FBgn0065773" protein_coding_gene "0008504=monoamine transmembrane transporter activity, 0015238=drug transmembrane transporter activity, 0005430=synaptic vesicle amine transmembrane transporter activity" "0015872=dopamine transport, 0055085=transmembrane transport, 0051608=histamine transport, 0015844=monoamine transport, 0015893=drug transport, 0006836=neurotransmitter transport, 0015842=synaptic vesicle amine transport" "0016021=integral component of membrane, 0008021=synaptic vesicle, 0031594=neuromuscular junction" "lethal (2) SH0459, vesicle transporter, vmat, DVMAT-B, dVMAT, Drosophila vesicular monoamine transporter, l(2)SH0459, Vmat, l(2)SH2 0459, vesicular monoamine transporter, CG6119, DVMAT-A, DVMAT, CG6139, CG33528, VMAT" "IPR004734=Multidrug resistance protein, IPR020846=Major facilitator superfamily domain, IPR011701=Major facilitator superfamily" CG33528 16-Dec-15 2015_12 "ENSDARG00000015110(slc18a2),ENSDARG00000030562" WBGene00000295(cat-1) "ENSXETG00000014640(BC075113.1),ENSXETG00000016485(BC090568.1),ENSXETG00000016493(TNeu067c02.1)" "ENSMUSG00000025094(Slc18a2),ENSMUSG00000036330(Slc18a1)" "ENSG00000165646(SLC18A2),ENSG00000036565(SLC18A1)" FBgn0032796 CG10188 http://flybase.net/reports/FBgn0032796.html protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity 0035025=positive regulation of Rho protein signal transduction "IPR015721=Rho GTP exchange factor, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR001849=Pleckstrin homology domain, IPR000219=Dbl homology (DH) domain" CG10188 16-Dec-15 2015_12 "ENSDARG00000042308,ENSDARG00000011157(arhgef18),ENSDARG00000060415(si:ch211-1o14.5),ENSDARG00000023868,ENSDARG00000040380(arhgef1),ENSDARG00000051709" WBGene00013681(Y105E8A.24) "ENSXETG00000006438(ARHGEF18),ENSXETG00000007623(AKAP13)" "ENSMUSG00000004568(Arhgef18),ENSMUSG00000028059(Arhgef2)" "ENSG00000104880(ARHGEF18),ENSG00000116584(ARHGEF2)" viable FBgn0250816 AGO3 Argonaute 3 http://flybase.net/reports/FBgn0250816.html "FBgn0086780, FBgn0066316, FBgn0058300, FBan0040300, FBgn0069062" protein_coding_gene "0003723=RNA binding, 0034584=piRNA binding" "0035194=posttranscriptional gene silencing by RNA, 0010529=negative regulation of transposition, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening" "0005737=cytoplasm, 0005829=cytosol, 0005739=mitochondrion, 0043186=P granule" "Argonaute3, Argonaute-3, BEST:LD15785, CG40300, AGO3, Ago-3, Ago3, ago3, dAgo3" "IPR003100=PAZ domain, IPR012337=Ribonuclease H-like domain, IPR003165=Piwi domain" CG40300 16-Dec-15 2015_12 ENSDARG00000041699(LOC100331962) "ENSXETG00000010533(PIWIL2),ENSXETG00000012572()" "ENSMUSG00000029423(Piwil1),ENSMUSG00000036912(Piwil4),ENSMUSG00000033644(Piwil2)" "ENSG00000125207(PIWIL1),ENSG00000184571(PIWIL3),ENSG00000134627(PIWIL4)" "viable,female sterile,male sterile,partially" "dorsal appendage,maternal effect,egg" FBgn0039748 CG15529 http://flybase.net/reports/FBgn0039748.html protein_coding_gene IPR000980=SH2 domain CG15529 16-Dec-15 2015_12 "ENSMUSG00000061132(Blnk),ENSMUSG00000002699(Lcp2)" viable FBgn0053510 CG33510 http://flybase.net/reports/FBgn0053510.html "FBgn0032912, FBtr0081506, FBpp0081034" protein_coding_gene CG14398 "IPR011009=Protein kinase-like domain, IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like" CG33510 16-Dec-15 2015_12 "WBGene00011797(T16G1.3),WBGene00011799(T16G1.5),WBGene00011801(T16G1.7),WBGene00018623(F48G7.12),WBGene00011800(T16G1.6),WBGene00011798(T16G1.4),WBGene00003673(nhr-83),WBGene00009877(F49C12.7),WBGene00017635(F20D6.5)" FBgn0034590 Magi Magi http://flybase.net/reports/FBgn0034590.html "FBgn0034591, FBgn0050388" protein_coding_gene "0004385=guanylate kinase activity, 0017160=Ral GTPase binding" "0016020=membrane, 0097482=muscle cell postsynaptic density, 0043195=terminal bouton" "Ima, CG30388, D-MAGI, CG15656, magi, ima, CG4117" "IPR001202=WW domain, IPR001478=PDZ domain" CG30388 16-Dec-15 2015_12 "ENSDARG00000003169(magi1),ENSDARG00000060061,ENSDARG00000070145(si:ch1073-268b21.1),ENSDARG00000021590(magi2)" WBGene00010444(magi-1) "ENSXETG00000013130(MAGI1),ENSXETG00000019711(MAGI2),ENSXETG00000013195(MAGI3)" "ENSMUSG00000045095(Magi1),ENSMUSG00000040003(Magi2),ENSMUSG00000052539(Magi3)" "ENSG00000151276(MAGI1),ENSG00000187391(MAGI2),ENSG00000081026(MAGI3)" "visible,wild-type,viable" "ommatidium,eye,scutellar bristle,supernumerary" FBgn0261862 whd withered http://flybase.net/reports/FBgn0261862.html "FBgn0004012, FBgn0027842, FBgn0043803" protein_coding_gene 0004095=carnitine O-palmitoyltransferase activity "0006979=response to oxidative stress, 0045471=response to ethanol, 0010038=response to metal ion, 0042594=response to starvation" "0012505=endomembrane system, 0005739=mitochondrion" "carnitine palmitoyltransferase 1, BEST:GH27794, mitochondrial carnitine palamitoyltransferase I, Cpt1, CPT1, gh27794, carnitine-O-palmitoyltransferase, carnitin-palmitoyl transferase-I, CPTI, mitochondrial carnitine palmitoyltransferase I, CG12891" IPR000542=Acyltransferase ChoActase/COT/CPT CG12891 16-Dec-15 2015_12 "ENSDARG00000062054(si:ch211-236l14.3),ENSDARG00000059770(LOC558088),ENSDARG00000058285(cpt1b),ENSDARG00000037943,ENSDARG00000061660(LOC100333227)" WBGene00012907(cpt-1) "ENSXETG00000012607(),ENSXETG00000020491(CPT1A),ENSXETG00000015426(CPT1B)" "ENSMUSG00000024900(Cpt1a),ENSMUSG00000078937(Cpt1b),ENSMUSG00000007783(Cpt1c)" "ENSG00000205560(CPT1B),ENSG00000110090(CPT1A),ENSG00000169169(CPT1C)" FBgn0036255 Atg12 Autophagy-related 12 http://flybase.net/reports/FBgn0036255.html protein_coding_gene "0031386=protein tag, 0019776=Atg8 ligase activity" "0006914=autophagy, 0000045=autophagic vacuole assembly, 0016236=macroautophagy, 0035071=salivary gland cell autophagic cell death, 0035096=larval midgut cell programmed cell death, 1902350=cellular response to chloroquine, 0048102=autophagic cell death" "0005737=cytoplasm, 0034274=Atg12-Atg5-Atg16 complex" "Autophagy-specific gene 12, CG10861, ATG12, atg12, autophagy related protein 12" "IPR029071=Ubiquitin-related domain, IPR007242=Ubiquitin-like protein Atg12" CG10861 16-Dec-15 2015_12 ENSDARG00000069545(atg12) YBR217W(ATG12) WBGene00002982(lgg-3) ENSXETG00000000129(ATG12) ENSMUSG00000032905(Atg12) ENSG00000145782(ATG12) "immune response defective,RU486 conditional,locomotor behavior defective,increased cell death,chemical conditional,viable" "embryonic/larval salivary gland,fat body,somatic clone,calorie restriction conditional,autophagic vacuole | somatic clone | calorie restriction conditional,intestinal stem cell,chemical conditional" DRSC09803 K -0.924716153 0.310048173 -0.911834318 0.642875924 -0.757104185 -2.313548335 FBgn0051988 CG31988 http://flybase.net/reports/FBgn0051988.html "FBgn0032932, FBgn0044608" protein_coding_gene 0008270=zinc ion binding "CG17401, anon-WO0140519.26, bs21c01.y1" "IPR001781=Zinc finger, LIM-type" CG31988 16-Dec-15 2015_12 WBGene00012379(Y1A5A.1) "ENSXETG00000022912(fhl3),ENSXETG00000002577(FHL2),ENSXETG00000001065(FHL5),ENSXETG00000019760(fhl1)" "ENSMUSG00000032643(Fhl3),ENSMUSG00000008136(Fhl2),ENSMUSG00000028259(Fhl5),ENSMUSG00000050035(Fhl4),ENSMUSG00000023092(Fhl1)" "ENSG00000183386(FHL3),ENSG00000115641(FHL2),ENSG00000112214(FHL5),ENSG00000022267(FHL1)" viable FBgn0039778 Jon99Fi Jonah 99Fi http://flybase.net/reports/FBgn0039778.html FBgn0001289 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG18030, Jon99F, Jonah 99F, SPH181" "IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain" CG18030 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" FBgn0029839 CG4660 http://flybase.net/reports/FBgn0029839.html FBgn0062925 protein_coding_gene BcDNA:RH58440 IPR029069=HotDog domain CG4660 16-Dec-15 2015_12 "ENSDARG00000059795(si:ch73-52e5.1),ENSDARG00000037345(si:ch73-52e5.2)" ENSMUSG00000056665(4930572J05Rik) ENSG00000130193(C8orf55) FBgn0035165 CG13887 http://flybase.net/reports/FBgn0035165.html protein_coding_gene 0006886=intracellular protein transport "0012505=endomembrane system, 0005783=endoplasmic reticulum, 0016021=integral component of membrane" IPR008417=B-cell receptor-associated protein 29/31 CG13887 16-Dec-15 2015_12 "ENSDARG00000044972(bcap31),ENSDARG00000016231(zgc:110731)" WBGene00021883(Y54G2A.18) "ENSXETG00000024749(Q6P890_XENTR),ENSXETG00000025669(BCAP29)" "ENSMUSG00000002015(Bcap31),ENSMUSG00000020650(Bcap29)" "ENSG00000185825(BCAP31),ENSG00000075790(BCAP29)" viable FBgn0038421 CG17931 http://flybase.net/reports/FBgn0038421.html FBgn0063723 protein_coding_gene 0005829=cytosol BcDNA:AT19233 IPR007513=Uncharacterised protein family SERF CG17931 16-Dec-15 2015_12 YDL085C-A() WBGene00021348(Y37E3.4) "ENSMUSG00000043770,ENSMUSG00000021643(Serf1)" "viable,fertile" FBgn0037607 CG8036 http://flybase.net/reports/FBgn0037607.html FBgn0062080 protein_coding_gene 0004802=transketolase activity "0031935=regulation of chromatin silencing, 0031122=cytoplasmic microtubule organization" "0005875=microtubule associated complex, 0005811=lipid particle, 0005829=cytosol" "transketolase, anon-WO0118547.344" "IPR020826=Transketolase binding site, IPR005475=Transketolase-like, pyrimidine-binding domain, IPR009014=Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II, IPR005474=Transketolase, N-terminal, IPR029061=Thiamin diphosphate-binding fold" CG8036 16-Dec-15 2015_12 "ENSDARG00000006019(tkt),ENSDARG00000029689(LOC557518)" "YPR074C(TKL1),YBR117C(TKL2)" WBGene00008506(tkt-1) "ENSXETG00000026656(TTpA007c10.1),ENSXETG00000015654(tkt)" "ENSMUSG00000025519(Tktl2),ENSMUSG00000021957(Tkt),ENSMUSG00000031397(Tktl1)" "ENSG00000163931(TKT),ENSG00000151005(TKTL2)" "lethal,viable,fertile" DRSC16366 EK 0.32016666 -0.176214142 -1.544800852 0.410189454 0.041681434 1.779288202 FBgn0034184 CG9646 http://flybase.net/reports/FBgn0034184.html protein_coding_gene IPR019141=Protein of unknown function DUF2045 CG9646 16-Dec-15 2015_12 WBGene00015866(C16E9.2) ENSXETG00000003062(C22orf9) ENSMUSG00000036046(5031439G07Rik) ENSG00000100364(KIAA0930) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0037592 CG11737 http://flybase.net/reports/FBgn0037592.html protein_coding_gene IPR026749=Transmembrane protein 135 CG11737 16-Dec-15 2015_12 ENSDARG00000069157(tmem135) WBGene00019345(tmem-135) ENSXETG00000010432() ENSMUSG00000039428(Tmem135) ENSG00000166575(TMEM135) "viable,fertile" FBgn0044028 Notum Notum http://flybase.net/reports/FBgn0044028.html "FBgn0005534, FBgn0016904, FBgn0036559, FBgn0061961, FBgn0067795, FBgn0067796" protein_coding_gene "0019213=deacetylase activity, 0052689=carboxylic ester hydrolase activity" "0048076=regulation of compound eye pigmentation, 0016055=Wnt signaling pathway, 0006507=GPI anchor release, 0006029=proteoglycan metabolic process, 0030178=negative regulation of Wnt signaling pathway, 0048190=wing disc dorsal/ventral pattern formation" 0005615=extracellular space "l(3)72Da, wingful, ntm, Wingful, CG13076, lethal(3)72CDf, notum, lethal(3)72Da, wf, Not, anon-WO0118547.482, anon-WO03062410.10, Nt, wingful/notum, Wf, anon-WO03062410.8, l(3)72CDf" IPR004963=Pectinacetylesterase/NOTUM CG13076 16-Dec-15 2015_12 "ENSDARG00000031126(notum3),ENSDARG00000067511" ENSXETG00000003001(NOTUM) ENSMUSG00000042988(Notum) ENSG00000185269(NOTUM) " embryonic stage | extended germ band , larval stage | third instar " " organism | segmentally repeated

, dorsal mesothoracic disc | dorsal/ventral compartment boundary

" "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,somatic clone,increased cell death,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,cell non-autonomous,viable" "wing,wing margin bristle,mesothoracic tergum,adult thorax,dorsal,ectopic,embryonic/first instar larval cuticle,denticle,leg,wing disc,mechanosensory ventral triple row bristle,somatic clone,external sensory organ precursor cell,denticle belt,rescuable maternal effect,eye,pigment cell,supernumerary,abdominal sternite bristle,dorsocentral bristle,wing sensillum,cell non-autonomous,sensory mother cell,medial triple row,denticle row 1,wing margin,mechanosensory chaeta,taste bristle,dorsal compartment,dorsal row,posterior" FBgn0014948 btl::tor btl::tor http://flybase.net/reports/FBgn0014948.html engineered_fusion_gene 16-Dec-15 2015_12 "visible,increased cell number,somatic clone" "wing,wing vein,embryonic/larval tracheal system,dorsal air sac primordium,somatic clone" FBgn0062589 Mod(var)1641 Mod(var)1641 http://flybase.net/reports/FBgn0062589.html gene "0030702=chromatin silencing at centromere, 0006342=chromatin silencing" 1641 16-Dec-15 2015_12 "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0015974 l(2)PC4-51 lethal (2) PC4-51 http://flybase.net/reports/FBgn0015974.html gene l(2)PC4-G 16-Dec-15 2015_12 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0003536 stp silver tips http://flybase.net/reports/FBgn0003536.html gene 16-Dec-15 2015_12 "visible,male sterile,viable,male,reduced" "macrochaeta,microchaeta" FBgn0033905 CG18324 http://flybase.net/reports/FBgn0033905.html protein_coding_gene 0022857=transmembrane transporter activity 0006839=mitochondrial transport 0031966=mitochondrial membrane "IPR018108=Mitochondrial substrate/solute carrier, IPR023395=Mitochondrial carrier domain" CG18324 16-Dec-15 2015_12 ENSDARG00000014802(si:ch211-268m12.5) YKL120W(OAC1) "ENSMUSG00000018740(Slc25a35),ENSMUSG00000040740(Slc25a34)" ENSG00000162461(SLC25A34) "viable,fertile" FBgn0005184 l(2)S11 lethal of Seto 11 http://flybase.net/reports/FBgn0005184.html gene 16-Dec-15 2015_12 "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg" FBgn0028608 l(2)W17 lethal (2) W17 http://flybase.net/reports/FBgn0028608.html gene l(2R)W17 16-Dec-15 2015_12 "lethal,recessive" FBgn0031030 Tao Tao http://flybase.net/reports/FBgn0031030.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0005524=ATP binding" "0048036=central complex development, 0035332=positive regulation of hippo signaling, 0042220=response to cocaine, 0016319=mushroom body development, 0035094=response to nicotine, 0001894=tissue homeostasis, 0035329=hippo signaling, 0006468=protein phosphorylation, 0036335=intestinal stem cell homeostasis, 0035330=regulation of hippo signaling, 0006915=apoptotic process, 0030707=ovarian follicle cell development, 0046621=negative regulation of organ growth, 0045471=response to ethanol, 0045807=positive regulation of endocytosis" "0045178=basal part of cell, 0005886=plasma membrane" "TAO1, CG14217, tao-1, tao1, tao, AAF48973, dTao-1, MARKK, Tao-1" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG14217 16-Dec-15 2015_12 ENSDARG00000060751(LOC798408) "ENSXETG00000011341(TAOK2),ENSXETG00000009438(taok1)" "ENSMUSG00000017291(Taok1),ENSMUSG00000061288(Taok3),ENSMUSG00000059981" "ENSG00000160551(TAOK1),ENSG00000135090(TAOK3),ENSG00000149930(TAOK2)" "lethal,recessive,viable,chemosensitive behavior defective,size defective,visible,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell number,somatic clone,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,fertile" "follicle cell,somatic clone,wing,eye,inter-ommatidial cell | pupal stage,head,adult cuticle,wing disc | third instar larval stage,eye disc,dorsal | third instar larval stage,posterior,ellipsoid body,mushroom body alpha-lobe,mushroom body beta-lobe,mushroom body gamma-lobe,adult mushroom body alpha'-lobe,adult mushroom body beta'-lobe,mushroom body vertical lobe" DRSC28431 IK 1.117810006 -2.14917207 -0.022359568 -1.362496271 0.45389412 1.648884309 FBgn0039632 Cul5 Cullin 5 http://flybase.net/reports/FBgn0039632.html protein_coding_gene 0031625=ubiquitin protein ligase binding "0016567=protein ubiquitination, 0007281=germ cell development, 0007295=growth of a germarium-derived egg chamber, 0051726=regulation of cell cycle, 0007528=neuromuscular junction development, 0007293=germarium-derived egg chamber formation, 0016360=sensory organ precursor cell fate determination, 0008285=negative regulation of cell proliferation, 0006511=ubiquitin-dependent protein catabolic process, 0008582=regulation of synaptic growth at neuromuscular junction" 0031466=Cul5-RING ubiquitin ligase complex "CUL5, Cullin, CG1401, Cul-5, Cul5, Cullin-5, cul-5, cullin-5, Cullin 5, cul5, Cullin5" "IPR016158=Cullin homology, IPR001373=Cullin, N-terminal, IPR016159=Cullin repeat-like-containing domain, IPR016157=Cullin, conserved site, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019559=Cullin protein, neddylation domain" CG1401 16-Dec-15 2015_12 ENSDARG00000004260(LOC100006147) WBGene00000840(cul-5) ENSMUSG00000032030(Cul5) ENSG00000166266(CUL5) "visible,lethal,increased cell number,lethal - all die before end of larval stage,some die during larval stage,conditional,viable,cell number defective,recessive,neuroanatomy defective" "macrochaeta,NMJ bouton,microchaeta,thecogen cell,ectopic,trichogen cell,eye,wing blade,heat sensitive,haltere,wing disc | third instar larval stage,arista,tarsal segment,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,supernumerary,sensory organ cell,adult thorax,antenna,wing,egg,pole cell,maternal effect,egg chamber,germarium,oocyte,polar follicle cell,nurse cell fusome,nurse cell" FBgn0051865 Ada1-1 transcriptional Adaptor 1-1 http://flybase.net/reports/FBgn0051865.html FBgn0064891 protein_coding_gene "0004402=histone acetyltransferase activity, 0003713=transcription coactivator activity" "0006366=transcription from RNA polymerase II promoter, 0043966=histone H3 acetylation, 0016573=histone acetylation" "0000124=SAGA complex, 0005634=nucleus" "ada1-1, Ada1-1, BcDNA:RE30472, CG31865, Ada1" IPR024738=Transcriptional coactivator Hfi1/Transcriptional adapter 1 CG31865 16-Dec-15 2015_12 ENSXETG00000000526(tada1l) ENSMUSG00000026563(Tada1) ENSG00000152382(TADA1) FBgn0039328 CHKov2 CHKov2 http://flybase.net/reports/FBgn0039328.html FBgn0003232 protein_coding_gene "refractory to sigma D, ref(3)D, CG10675" "IPR015897=CHK kinase-like, IPR004119=Protein of unknown function DUF227, IPR011009=Protein kinase-like domain" CG10675 16-Dec-15 2015_12 "WBGene00019101(F59B1.10),WBGene00019100(F59B1.8)" viable FBgn0029858 CG15896 http://flybase.net/reports/FBgn0029858.html protein_coding_gene CG15896 16-Dec-15 2015_12 ENSMUSG00000021023(1110008L16Rik) ENSG00000100890(KIAA0391) FBgn0037633 CG9839 http://flybase.net/reports/FBgn0037633.html protein_coding_gene IPR029526=PiggyBac transposable element-derived protein CG9839 16-Dec-15 2015_12 "ENSXETG00000015805(),ENSXETG00000003333(),ENSXETG00000010481(),ENSXETG00000015956(),ENSXETG00000017435(),ENSXETG00000027600(),ENSXETG00000006521(),ENSXETG00000012643(),ENSXETG00000006403(),ENSXETG00000006059(),ENSXETG00000027110(),ENSXETG00000023283(),ENSXETG00000021687(),ENSXETG00000019382(),ENSXETG00000027396(),ENSXETG00000010484(),ENSXETG00000027127(),ENSXETG00000026139(),ENSXETG00000001009(),ENSXETG00000025576(),ENSXETG00000025108(),ENSXETG00000025102(),ENSXETG00000013560(),ENSXETG00000024847(),ENSXETG00000022692(),ENSXETG00000012055(),ENSXETG00000008791(),ENSXETG00000005537(),ENSXETG00000002391(),ENSXETG00000012655(),ENSXETG00000027102(),ENSXETG00000007053(),ENSXETG00000024873()" ENSG00000182405(PGBD4) viable FBgn0026401 Nipped-B Nipped-B http://flybase.net/reports/FBgn0026401.html "FBan0017704, FBgn0010505, FBgn0020393, FBgn0058281" protein_coding_gene "0005515=protein binding, 0003682=chromatin binding" "0070193=synaptonemal complex organization, 0006355=regulation of transcription, DNA-templated, 0071733=transcriptional activation by promoter-enhancer looping, 0010628=positive regulation of gene expression, 0034088=maintenance of mitotic sister chromatid cohesion, 0007064=mitotic sister chromatid cohesion" "0008278=cohesin complex, 0035327=transcriptionally active chromatin, 0043234=protein complex, 0005634=nucleus, 0032116=SMC loading complex, 0005700=polytene chromosome, 0000795=synaptonemal complex, 0005654=nucleoplasm" "NipB, nipped-B, CG40281, Nipped B, Nipped, NIPPED-B, CG17704, l(2)02047" "IPR024986=Sister chromatid cohesion C-terminal domain, IPR026003=HEAT repeat associated with sister chromatid cohesion protein, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG17704 16-Dec-15 2015_12 ENSDARG00000061074 YDR180W(SCC2) WBGene00004166(pqn-85) ENSMUSG00000022141(Nipbl) ENSG00000164190(NIPBL) embryonic stage -- adult stage "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,mitotic cell cycle defective,viable,lethal - all die before end of larval stage,some die during larval stage,visible,dominant,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "synaptonemal complex,wing blade,male genitalia,adult abdomen" DRSC07815 K -0.824601686 0.072978824 0.128906038 0.946324582 0.947222861 2.055067903 FBgn0033017 CG10465 http://flybase.net/reports/FBgn0033017.html FBan0010465 protein_coding_gene 0051260=protein homooligomerization "IPR011333=POZ domain, IPR003131=Potassium channel tetramerisation-type BTB domain, IPR000210=BTB/POZ domain" CG10465 16-Dec-15 2015_12 "ENSDARG00000017115(kctd10),ENSDARG00000041565(tnfaip1),ENSDARG00000044769(kctd13)" WBGene00008425(D2045.8) "ENSXETG00000019443(tnfaip1),ENSXETG00000018588(kctd10)" "ENSMUSG00000001098(Kctd10),ENSMUSG00000017615(Tnfaip1),ENSMUSG00000030685(Kctd13)" "ENSG00000110906(KCTD10),ENSG00000109079(TNFAIP1),ENSG00000174943(KCTD13)" "viable,fertile" DRSC04848 K -0.584044141 0.510038795 -0.325417715 0.138431644 -1.97004794 -1.612206289 FBgn0027074 CG17324 http://flybase.net/reports/FBgn0027074.html FBgn0032712 protein_coding_gene "0016758=transferase activity, transferring hexosyl groups, 0008194=UDP-glycosyltransferase activity" "0006011=UDP-glucose metabolic process, 0006805=xenobiotic metabolic process" 0005783=endoplasmic reticulum "BEST:GH06505, GH06505" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG17324 16-Dec-15 2015_12 "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "viable,fertile" FBgn0033555 RpS15Ab Ribosomal protein S15Ab http://flybase.net/reports/FBgn0033555.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0007052=mitotic spindle organization, 0000022=mitotic spindle elongation" 0022627=cytosolic small ribosomal subunit "CG12324, RpS15A, CT22283" IPR000630=Ribosomal protein S8 CG12324 16-Dec-15 2015_12 ENSDARG00000010160(rps15a) "YLR367W(RPS22B),YJL190C(RPS22A)" WBGene00004491(rps-22) ENSXETG00000002942(RPS15A) "ENSMUSG00000008683(Rps15a),ENSMUSG00000067058(Gm10196),ENSMUSG00000067351" ENSG00000134419(RPS15A) DRSC19831 EK -0.053939534 0.277854648 0.438674626 -1.605618004 1.293135208 5.622332563 FBgn0028399 TMS1 TMS1 http://flybase.net/reports/FBgn0028399.html protein_coding_gene "0005886=plasma membrane, 0016020=membrane" "TMS1d, CG4672, Target of methylation-induced silencing 1" "IPR005016=Serine incorporator/TMS membrane protein, IPR029559=Membrane protein Tms1-like" CG4672 16-Dec-15 2015_12 "ENSDARG00000053425,ENSDARG00000056532(serinc2),ENSDARG00000009106(serinc1),ENSDARG00000018900" YDR105C(TMS1) "WBGene00021956(Y57E12AL.1),WBGene00011250(R11H6.2)" "ENSXETG00000023292(tde2),ENSXETG00000001778(tde1),ENSXETG00000012918(tde2l)" "ENSMUSG00000019877(Serinc1),ENSMUSG00000017707(Serinc3),ENSMUSG00000023232(Serinc2)" "ENSG00000111897(SERINC1),ENSG00000132824(SERINC3),ENSG00000168528(SERINC2)" "viable,fertile" FBgn0023388 Dap160 Dynamin associated protein 160 http://flybase.net/reports/FBgn0023388.html protein_coding_gene "0005515=protein binding, 0005509=calcium ion binding" "0008104=protein localization, 0002052=positive regulation of neuroblast proliferation, 0048488=synaptic vesicle endocytosis, 0045746=negative regulation of Notch signaling pathway, 0045860=positive regulation of protein kinase activity, 0007269=neurotransmitter secretion, 0051124=synaptic growth at neuromuscular junction" "0042734=presynaptic membrane, 0045179=apical cortex, 0005737=cytoplasm, 0008021=synaptic vesicle, 0005886=plasma membrane" "noncoding_4110, Intersectin, DAP-160, Dap160/intersectin, dap160, intersectin, p160, dynamin associated protein 160, CG1099, Dynamin-associated protein 160 kDa, DAP160" "IPR002048=EF-hand domain, IPR001452=SH3 domain, IPR000261=EH domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG1099 16-Dec-15 2015_12 "ENSDARG00000054973(si:ch211-175f11.2),ENSDARG00000000161(si:dkey-266k12.1),ENSDARG00000000086(itsn1)" WBGene00006405(itsn-1) "ENSXETG00000014182(itsn1),ENSXETG00000026098()" "ENSMUSG00000020640(Itsn2),ENSMUSG00000022957(Itsn1)" "ENSG00000205726(ITSN1),ENSG00000198399(ITSN2)" larval stage | third instar " bouton

, neuromuscular junction

" "neuroanatomy defective,lethal,viable,wild-type,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,uncoordinated,paralytic,heat sensitive,neurophysiology defective,endocytosis defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "NMJ bouton,supernumerary,neuromuscular junction,bouton,synaptic vesicle,embryonic/larval neuromuscular junction,larval neuroblast & larval brain,embryonic/larval neuroblast,larval neuroblast & larval brainwor.PA,eo sensory structure,eo neuron,macrochaeta" FBgn0085408 Shroom Shroom http://flybase.net/reports/FBgn0085408.html "FBgn0033922, FBgn0033923, FBgn0040749" protein_coding_gene "0051015=actin filament binding, 0003779=actin binding" "0042249=establishment of planar polarity of embryonic epithelium, 0030950=establishment or maintenance of actin cytoskeleton polarity, 0071896=protein localization to adherens junction, 0090251=protein localization involved in establishment of planar polarity, 0000902=cell morphogenesis, 0032438=melanosome organization, 0016477=cell migration" "0005886=plasma membrane, 0005912=adherens junction, 0005856=cytoskeleton, 0005923=bicellular tight junction, 0030864=cortical actin cytoskeleton" "CG13944, CG13942, CG34379, Shrm, dmShroom, CG8603, dShrm" "IPR027685=Shroom family, IPR014799=Apx/Shrm Domain 2, IPR030493=Protein Shroom" CG34379 16-Dec-15 2015_12 "ENSXETG00000004167(SHROOM1),ENSXETG00000019941(SHROOM3)" "ENSMUSG00000045180(Shroom2),ENSMUSG00000029381(Shroom3),ENSMUSG00000068270(Shroom4)" "ENSG00000138771(SHROOM3),ENSG00000146950(SHROOM2),ENSG00000158352(SHROOM4)" FBgn0042102 CG18745 http://flybase.net/reports/FBgn0042102.html protein_coding_gene "IPR014756=Immunoglobulin E-set, IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain" CG18745 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" WBGene00011732(T12D8.4) "ENSXETG00000013606(ARRDC2),ENSXETG00000018085(arrdc3),ENSXETG00000002108(ARRDC4),ENSXETG00000011050(TXNIP)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" "ENSG00000105643(ARRDC2),ENSG00000113369(ARRDC3),ENSG00000140450(ARRDC4),ENSG00000117289(TXNIP)" viable FBgn0028707 Mt2 Methyltransferase 2 http://flybase.net/reports/FBgn0028707.html FBgn0029313 protein_coding_gene "0008168=methyltransferase activity, 0008175=tRNA methyltransferase activity, 0003886=DNA (cytosine-5-)-methyltransferase activity" "0002230=positive regulation of defense response to virus by host, 0008340=determination of adult lifespan, 0006306=DNA methylation, 0045089=positive regulation of innate immune response, 0009408=response to heat, 0044026=DNA hypermethylation, 0006979=response to oxidative stress, 0000723=telomere maintenance, 0016458=gene silencing, 0030488=tRNA methylation, 0043045=DNA methylation involved in embryo development" "0010494=cytoplasmic stress granule, 0005730=nucleolus, 0016363=nuclear matrix, 0000786=nucleosome, 0000790=nuclear chromatin, 0005634=nucleus" "nmt2, DNMT, CG10692, Mt2, DNMT2, DmMT2, Dnmt2, DNA(5-cytosine) methyltransferase, Dnmt, dnmt2, dDNMT, dDNMT2, cytosine-5 methyltransferase, DNA methyltransferase 2, dDnmt2" "IPR031303=DNA methylase, C-5 cytosine-specific, conserved site, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR001525=C-5 cytosine methyltransferase" CG10692 16-Dec-15 2015_12 ENSDARG00000034518(trdmt1) ENSXETG00000027671(Q6DIS0_XENTR) ENSMUSG00000026723(Trdmt1) ENSG00000107614(TRDMT1) " adult stage | female , embryonic stage && larval stage , embryonic stage " " organism

, ovary

" "immune response defective,viable,fertile,heat stress response defective,chemical sensitive,recessive,melanotic mass phenotype,conditional,non-suppressor of variegation,suppressor of variegation,dominant,short lived,stress response defective,long lived,chemical resistant" eye disc posterior to the morphogenetic furrow FBgn0030746 CG9981 http://flybase.net/reports/FBgn0030746.html protein_coding_gene "0005524=ATP binding, 0004012=phospholipid-translocating ATPase activity, 0000287=magnesium ion binding" 0045332=phospholipid translocation 0016021=integral component of membrane DmCG9981 "IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR023214=HAD-like domain, IPR001757=P-type ATPase, IPR006539=P-type ATPase, subfamily IV, IPR023299=P-type ATPase, cytoplasmic domain N" CG9981 16-Dec-15 2015_12 "ENSDARG00000054028(si:dkey-211e20.10),ENSDARG00000008413(si:dkey-251i8.1),ENSDARG00000036442(atp11c)" "ENSXETG00000016814(ATP11B),ENSXETG00000001905(ATP11A),ENSXETG00000018290(ATP11C)" "ENSMUSG00000037400(Atp11b),ENSMUSG00000031441(Atp11a),ENSMUSG00000062949(Atp11c)" "ENSG00000058063(ATP11B),ENSG00000068650(ATP11A),ENSG00000101974(ATP11C)" viable FBgn0037818 CG6465 http://flybase.net/reports/FBgn0037818.html protein_coding_gene "0004046=aminoacylase activity, 0008237=metallopeptidase activity" "0006508=proteolysis, 0006520=cellular amino acid metabolic process" 0005737=cytoplasm "IPR002933=Peptidase M20, IPR001261=ArgE/DapE/ACY1/CPG2/YscS, conserved site, IPR011650=Peptidase M20, dimerisation domain, IPR010159=N-acyl-L-amino-acid amidohydrolase" CG6465 16-Dec-15 2015_12 "ENSDARG00000004845(LOC100001620),ENSDARG00000038475(zgc:55605)" "WBGene00007507(C10C5.3),WBGene00007508(C10C5.4),WBGene00007509(C10C5.5),WBGene00015509(C06A6.4)" ENSXETG00000000089(acy1) ENSMUSG00000023262(Acy1) ENSG00000114786(ACY1) "viable,fertile" FBgn0043362 bchs blue cheese http://flybase.net/reports/FBgn0043362.html "FBgn0031748, FBgn0031750, FBgn0062881" protein_coding_gene 0046872=metal ion binding "0031396=regulation of protein ubiquitination, 0048749=compound eye development, 0007041=lysosomal transport, 0050807=regulation of synapse organization, 0022416=chaeta development, 0048666=neuron development" "0030424=axon, 0048786=presynaptic active zone, 0031594=neuromuscular junction, 0005737=cytoplasm" "Alfy, alfy, Blue Cheese, DBEACH1, Bchs, Beached 1, EP2299, Blue cheese, CG14001, Beached1, Beach1, dbeach1, CG9011, beached, bchd, Beached, BcDNA:SD12984" "IPR000409=BEACH domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR019775=WD40 repeat, conserved site, IPR017455=Zinc finger, FYVE-related, IPR011011=Zinc finger, FYVE/PHD-type, IPR023362=PH-BEACH domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR016024=Armadillo-type fold, IPR000306=FYVE zinc finger, IPR011989=Armadillo-like helical, IPR001680=WD40 repeat" CG14001 16-Dec-15 2015_12 WBGene00007752(C26H9A.2) ENSXETG00000006279() ENSMUSG00000043940(Wdfy3) ENSG00000163625(WDFY3) "neuroanatomy defective,male fertile,female fertile,short lived,male,visible,wild-type,fertile,viable" "glial cell,eye disc,protocerebrum,ommatidium,retina,fan-shaped body,ellipsoid body,deuterocerebrum,lamina,medulla,subesophageal ganglion,rhabdomerecl7),brain,adult central nervous system,eye,growth coneGMR.PF,neuron & eye photoreceptor cellGMR.PF,growth cone & eye photoreceptor cellGMR.PF,dorsocentral bristle,scutellar bristle,adult abdomen & microchaeta-537.4,anterior fascicle & synapse,intersegmental nerve,embryonic/larval brain | third instar larval stage,embryonic/larval brain" FBgn0040069 vanin-like vanin-like http://flybase.net/reports/FBgn0040069.html "FBgn0029847, FBgn0052754" protein_coding_gene 0017159=pantetheine hydrolase activity 0006807=nitrogen compound metabolic process 0019898=extrinsic component of membrane "Pantetheine hydrolase, CG32754, Vanin-like, CG3648" "IPR012101=Biotinidase, eukaryotic, IPR003010=Carbon-nitrogen hydrolase" CG32754 16-Dec-15 2015_12 ENSDARG00000006926 "ENSXETG00000000104(BC087969.1),ENSXETG00000008991(BTD)" "ENSMUSG00000021900(Btd),ENSMUSG00000037440(Vnn1),ENSMUSG00000020010(Vnn3)" "ENSG00000169814(BTD),ENSG00000112299(VNN1),ENSG00000112303(VNN2),ENSG00000093134" "viable,partially lethal - majority die,some die during pupal stage" FBgn0033978 Cyp6a23 Cyp6a23 http://flybase.net/reports/FBgn0033978.html protein_coding_gene "0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "CG10242, 6a23, cytochrome P450, Cypa23, cyp6a23" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG10242 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00011675(cyp-13A3),WBGene00000372(cyp-13A7),WBGene00011672(cyp-13A5),WBGene00011671(cyp-13A4),WBGene00011676(cyp-13A2),WBGene00011673(cyp-13A6)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" viable FBgn0082582 tmod tropomodulin http://flybase.net/reports/FBgn0082582.html "FBgn0011716, FBgn0010731, FBgn0039785, FBgn0039786" protein_coding_gene "0003779=actin binding, 0005523=tropomyosin binding" "0007476=imaginal disc-derived wing morphogenesis, 0051694=pointed-end actin filament capping, 0007010=cytoskeleton organization" "0005938=cell cortex, 0045169=fusome" "sanpodo, unnamed, spdo, CT41421, E42, CT3919, CG15540, CG11493, Tropomodulin, 1309/10, Tmod, l(3)S130910, l(3)00848, tropmodulin, CG1539" "IPR030137=Tropomodulin, invertebrate, IPR004934=Tropomodulin, IPR003590=Leucine-rich repeat, ribonuclease inhibitor subtype" CG1539 16-Dec-15 2015_12 "ENSDARG00000020890(tmod4),ENSDARG00000002571" WBGene00006823(unc-94) "ENSXETG00000020747(tmod3),ENSXETG00000008139(tmod4),ENSXETG00000010173(TMOD1),ENSXETG00000022132(LMOD2)" "ENSMUSG00000028328(Tmod1),ENSMUSG00000058587(Tmod3),ENSMUSG00000005628(Tmod4),ENSMUSG00000032186(Tmod2)" "ENSG00000136842(TMOD1),ENSG00000138594(TMOD3),ENSG00000163157(TMOD4),ENSG00000128872(TMOD2)" " larval stage--adult stage , embryonic stage | stage >=12 , embryonic stage -- adult stage , embryonic stage | stage 14-16 , embryonic stage | >=9-12 hr , larval stage--pupal stage , embryonic stage | stage >=9 , pupal stage , embryonic stage " " embryonic peripheral nervous system

, trichogen cell

, embryonic central nervous system | precursor

, tormogen cell

" " adult stage | male , adult stage , adult stage| female , pupal stage , embryonic stage -- adult stage , adult stage | day 1 , pupal stage && adult stage " " adult abdomen

, adult head

, muscle cell

, indirect flight muscle

, adult thorax

" "lethal,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,female fertile,germline clone,flight defective,heat sensitive" "striated muscle thin filamentMef2.PR,striated muscle thin filamentUH3,indirect flight muscle,indirect flight muscle & striated muscle thin filament,indirect flight muscle & striated muscle thick filament,indirect flight muscle & Z disc,myofibrilUH3,sarcomereUH3" DRSC15076 K -0.322387649 0.949061055 -0.168533051 0.939995242 2.081276554 0.690822899 FBgn0027498 CG2061 http://flybase.net/reports/FBgn0027498.html protein_coding_gene 0004930=G-protein coupled receptor activity 0007186=G-protein coupled receptor signaling pathway BcDNA:LD28247 "IPR007822=Lanthionine synthetase C-like, IPR020464=LanC-like protein, eukaryotic" CG2061 16-Dec-15 2015_12 "ENSDARG00000013741(lancl1),ENSDARG00000045465(zgc:158293)" ENSXETG00000018623(LANCL3) ENSMUSG00000047344(Lancl3) ENSG00000147036(LANCL3) viable FBgn0267433 kl-5 male fertility factor kl5 http://flybase.net/reports/FBgn0267433.html "FBgn0010386, FBgn0040029, FBgn0058444, FBan0040444, FBgn0001315, FBan0041497, FBgn0085658" protein_coding_gene "0003774=motor activity, 0008017=microtubule binding, 0042623=ATPase activity, coupled, 0016887=ATPase activity, 0003777=microtubule motor activity, 0005524=ATP binding" 0007018=microtubule-based movement "0005875=microtubule associated complex, 0005858=axonemal dynein complex" "male fertility factor kl-5, CG40444, Y-linked flagellar dynein, CG17616, DhcYh3, CG45786, Lms4, Kl-5, Dhc, dynein-related heavy chain, kl5, Dhc-Yh3, Dynein heavy chain in Yh3, CG12573, CG41497, unnamed" "IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR011704=ATPase, dynein-related, AAA domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR003593=AAA+ ATPase domain, IPR026983=Dynein heavy chain, IPR013594=Dynein heavy chain, domain-1, IPR004273=Dynein heavy chain domain, IPR013602=Dynein heavy chain, domain-2, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG45786 16-Dec-15 2015_12 " adult stage | male , adult stage " " organism

, testis

" DRSC19615 I 1.516630924 -0.326109663 0.060611754 0.313036937 FBgn0034933 CG3735 http://flybase.net/reports/FBgn0034933.html protein_coding_gene 0022008=neurogenesis 0005634=nucleus "IPR010678=Digestive organ expansion factor, predicted" CG3735 16-Dec-15 2015_12 ENSDARG00000017696(def) YIL091C(UTP25) WBGene00012756(Y41C4A.9) ENSXETG00000000216(C1orf107) ENSMUSG00000016181(AA408296) ENSG00000117597(DIEXF) "viable,fertile,lethal,recessive,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC04411 K 0.586279226 -0.21506252 -0.900198591 0.151494817 -1.726632855 -0.369966135 FBgn0260962 pic piccolo http://flybase.net/reports/FBgn0260962.html "FBgn0003084, FBgn0027049" protein_coding_gene "0005515=protein binding, 0003684=damaged DNA binding" "0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0050832=defense response to fungus, 0035220=wing disc development, 0007307=eggshell chorion gene amplification, 0007095=mitotic G2 DNA damage checkpoint, 0006289=nucleotide-excision repair, 0006974=cellular response to DNA damage stimulus, 0045732=positive regulation of protein catabolic process" "0005737=cytoplasm, 0005634=nucleus" "1258/16, damaged DNA binding protein 1, 0263/16, DDB-1, Piccolo, 153636_at, d-ddb1, Ddb1, Damage-specific DNA binding protein 1, Dbd1, l(3)S136603, CG7769, 263/16, Drosophila damage-specific DNA-binding protein 1, l(3)87Dh, dDdb1, DDB1, 1366/03, D-DDB1" "IPR017986=WD40-repeat-containing domain, IPR031297=DNA damage-binding protein 1, IPR004871=Cleavage/polyadenylation specificity factor, A subunit, C-terminal" CG7769 16-Dec-15 2015_12 WBGene00010890(ddb-1) ENSXETG00000008820(DDB1) ENSMUSG00000024740(Ddb1) ENSG00000167986(DDB1) DRSC16639 I -1.117300938 -2.138487555 -1.09675522 -0.71885282 -0.422909447 -0.358336135 FBgn0037220 CG14641 http://flybase.net/reports/FBgn0037220.html FBan0014641 protein_coding_gene "0003676=nucleic acid binding, 0003729=mRNA binding, 0046872=metal ion binding, 0000166=nucleotide binding" "0000398=mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005634=nucleus, 0071011=precatalytic spliceosome" cg14641 "IPR000571=Zinc finger, CCCH-type, IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG14641 16-Dec-15 2015_12 ENSDARG00000010238(rbm22) WBGene00011722(T11G6.8) ENSXETG00000020435(RBM22) ENSMUSG00000024604(Rbm22) ENSG00000086589(RBM22) "visible,partially lethal - majority die,some die during pupal stage" "heart primordium,chaeta,supernumerary,mesothoracic tergum" DRSC12227 I -0.175302174 1.971005021 1.007785317 1.15357981 -0.261834252 0.10818212 FBgn0086532 Spt-I Serine palmitoyltransferase subunit I http://flybase.net/reports/FBgn0086532.html "FBgn0065392, FBgn0033800" protein_coding_gene "0004758=serine C-palmitoyltransferase activity, 0030170=pyridoxal phosphate binding" 0009058=biosynthetic process 0017059=serine C-palmitoyltransferase complex "CG4016, l(2)SH1626, Spt1, lethal (2) SH1626, SPT-I, lcb1, l(2)SH2 1626, Serine palmitoyltransferase subunit I" "IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR004839=Aminotransferase, class I/classII, IPR015424=Pyridoxal phosphate-dependent transferase" CG4016 16-Dec-15 2015_12 ENSDARG00000042995(sptlc1) YMR296C(LCB1) WBGene00016020(sptl-1) ENSXETG00000014644(SPTLC1) ENSMUSG00000021468(Sptlc1) ENSG00000090054(SPTLC1) DRSC06860 I 1.766104995 0.810334239 -0.243553813 0.30063024 -0.142366571 -0.309840471 FBgn0051894 CG31894 http://flybase.net/reports/FBgn0051894.html protein_coding_gene 16-Dec-15 2015_12 DRSC26190 K -0.57769996 0.277964178 0.089043711 -0.399753771 0.28057964 -1.767501283 FBgn0011666 msi musashi http://flybase.net/reports/FBgn0011666.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0000900=translation repressor activity, nucleic acid binding, 0003723=RNA binding, 0045182=translation regulator activity" "0042078=germ-line stem cell division, 0017148=negative regulation of translation, 0006397=mRNA processing, 0022416=chaeta development, 0006417=regulation of translation, 0071456=cellular response to hypoxia, 0001709=cell fate determination, 0019827=stem cell maintenance" 0005634=nucleus "CG5099, dMsi, DMSIDNA, mushashi, MSI, clone 2.35, anon-EST:Liang-2.35, Msi, musashi, SIDNA" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG5099 16-Dec-15 2015_12 "ENSDARG00000031809(LOC100147844),ENSDARG00000058818(rbm38)" YOL123W(HRP1) "viable,fertile,wild-type,lethal,recessive,visible,meiotic cell cycle defective" "microchaeta & scutum,macrochaeta & scutum,testis,testis sheath muscle,socket,thecogen cell,neuron & microchaeta,neuron & macrochaeta,glial cell & macrochaeta,thecogen cell & medial triple row,thecogen cell & dorsal triple row,thecogen cell & twin sensillum of margin 1,thecogen cell & twin sensillum of margin 2,ommatidium,rhabdomere,trichogen cell,supernumerary,external sensory organ,germline stem cell,somatic clone,spermatogonium,tormogen cell" DRSC17003 K -1.347061584 -0.81107281 -0.916477796 -1.010736633 0.193288203 1.818307464 FBgn0037244 CG14647 http://flybase.net/reports/FBgn0037244.html FBan0014647 protein_coding_gene 0051260=protein homooligomerization "IPR003131=Potassium channel tetramerisation-type BTB domain, IPR000210=BTB/POZ domain, IPR001646=Pentapeptide repeat, IPR011333=POZ domain" CG14647 16-Dec-15 2015_12 "ENSDARG00000021209(zgc:113115),ENSDARG00000010603(kctd9)" "WBGene00015914(C17F4.8),WBGene00016546(C40A11.3),WBGene00016549(C40A11.6),WBGene00016550(C40A11.7),WBGene00017705(F22E5.6),WBGene00022572(ZC239.14),WBGene00022573(ZC239.15),WBGene00017707(F22E5.8),WBGene00022567(ZC239.4),WBGene00016545(C40A11.2),WBGene00015113(B0281.6),WBGene00022574(ZC239.16),WBGene00016547(C40A11.4),WBGene00017710(F22E5.12),WBGene00011486(T05E12.3),WBGene00022566(ZC239.3),WBGene00019340(K02F6.6)" ENSMUSG00000034327(Kctd9) ENSG00000104756(KCTD9) "viable,lethal" FBgn0040056 CG17698 http://flybase.net/reports/FBgn0040056.html "FBan0017698, FBgn0058297" protein_coding_gene "0004683=calmodulin-dependent protein kinase activity, 0005524=ATP binding, 0005509=calcium ion binding, 0004674=protein serine/threonine kinase activity" 0006468=protein phosphorylation 0005737=cytoplasm "CAMKIIb, CG40297, CAMKIIB" "IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR020636=Calcium/calmodulin-dependent/calcium-dependent protein kinase, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain" CG17698 16-Dec-15 2015_12 "ENSDARG00000035452(camkk1),ENSDARG00000015134(zgc:194737)" WBGene00000518(ckk-1) ENSXETG00000020962(CAMKK2) "ENSMUSG00000029471(Camkk2),ENSMUSG00000020785(Camkk1)" "ENSG00000110931(CAMKK2),ENSG00000004660(CAMKK1)" viable FBgn0003134 Pp1ë±-96A Protein phosphatase 1ë± at 96A http://flybase.net/reports/FBgn0003134.html protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0016787=hydrolase activity" "0006470=protein dephosphorylation, 0050829=defense response to Gram-negative bacterium, 0045089=positive regulation of innate immune response" 0000164=protein phosphatase type 1 complex "CG6593, DmPp1-96A, PP1c 96A, PP1alpha[[1]], protein phosphatase 1, Pp1-96A, 96A, pp1alpha96A, unnamed, PP1c, PP1 alpha96a, Pp1alpha-96A, PP1alpha96A, PP1 96A, PP1" "IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG6593 16-Dec-15 2015_12 "ENSDARG00000003486(ppp1caa),ENSDARG00000071566(ppp1cab)" YER133W(GLC7) WBGene00001748(gsp-2) ENSXETG00000024480(ppp1cc) "ENSMUSG00000040385(Ppp1ca),ENSMUSG00000004455(Ppp1cc)" "ENSG00000186298(PPP1CC),ENSG00000172531(PPP1CA)" " adult stage , embryonic stage " "viable,fertile,lethal,immune response defective,conditional" enterocyte FBgn0037993 dpr15 defective proboscis extension response 15 http://flybase.net/reports/FBgn0037993.html protein_coding_gene 0007606=sensory perception of chemical stimulus "Dpr15, CG10095, Dpr-15, CT28423, dpr15" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain" CG10095 16-Dec-15 2015_12 "ENSDARG00000058564,ENSDARG00000015607,ENSDARG00000029838,ENSDARG00000038496,ENSDARG00000028912,ENSDARG00000052459,ENSDARG00000071050(LOC100148207),ENSDARG00000071261,ENSDARG00000070065" "ENSMUSG00000054793(Cadm4),ENSMUSG00000032076(Cadm1),ENSMUSG00000064115(Cadm2),ENSMUSG00000005338(Cadm3)" "ENSG00000105767(CADM4),ENSG00000182985(CADM1),ENSG00000175161(CADM2),ENSG00000162706(CADM3)" "partially lethal - majority die,visible,body color defective,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC14187 IE -0.485308334 -1.528640449 1.326388548 -2.232291019 0.46110335 -0.273931199 FBgn0086134 Prosë±2 Proteasome ë±2 subunit http://flybase.net/reports/FBgn0086134.html "FBgn0010405, FBgn0024727" protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" "0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0008283=cell proliferation, 0090307=mitotic spindle assembly, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0000502=proteasome complex, 0019773=proteasome core complex, alpha-subunit complex, 0005839=proteasome core complex" "PROS Dm25, Su(DTS)-1, alpha-subunit of 20S proteasome, alpha2 subunit, PROS-Dm25g, Proteosome, CG5266, dalpha2, alpha2, 20s proteasome, PSA2_DROME, 153303_at, Proteasome subunit alpha-type 2, Prot. 25 Kda, Su(DTS), 20S proteasome, alpha2_dm, Pros25, Proteasome 25kD subunit, Prosalpha2, PRC3, Alpha-2, alpha-2" "IPR001353=Proteasome, subunit alpha/beta, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR023332=Proteasome A-type subunit" CG5266 16-Dec-15 2015_12 "ENSDARG00000040121(psma2),ENSDARG00000035679(si:rp71-45k5.4)" YML092C(PRE8) WBGene00003923(pas-2) ENSXETG00000001853(psma2) ENSMUSG00000015671(Psma2) ENSG00000106588(PSMA2) DRSC16798 IEK 0.057792183 -2.905284425 -3.526330476 -1.686341625 1.627303321 1.963609334 FBgn0015663 Dot Dorothy http://flybase.net/reports/FBgn0015663.html FBgn0031553 protein_coding_gene "0050488=ecdysteroid UDP-glucosyltransferase activity, 0016758=transferase activity, transferring hexosyl groups" 0008152=metabolic process CG2788 IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG2788 16-Dec-15 2015_12 "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "viable,visible,recessive" DRSC00748 K -0.543333073 0.458708028 -0.664736845 0.652753375 -1.571262226 0.024151163 FBgn0010416 TH1 TH1 http://flybase.net/reports/FBgn0010416.html protein_coding_gene 0003729=mRNA binding "0034244=negative regulation of transcription elongation from RNA polymerase II promoter, 0022008=neurogenesis, 0007070=negative regulation of transcription from RNA polymerase II promoter during mitosis" "0017053=transcriptional repressor complex, 0032021=NELF complex, 0005634=nucleus" "NELF-D, NELF, CG9984" IPR006942=TH1 protein CG9984 16-Dec-15 2015_12 ENSDARG00000021097(th1l) ENSXETG00000024187(th1l) ENSMUSG00000016253(Th1l) ENSG00000101158(TH1L) " embryonic stage , adult stage | female " "lethal,some die during second instar larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0030776 CG4653 http://flybase.net/reports/FBgn0030776.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH179 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site" CG4653 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" viable DRSC22857 I -0.382668935 -2.71834011 0.306100827 0.032357706 0.226747445 0.020581592 FBgn0259204 CG42308 http://flybase.net/reports/FBgn0259204.html protein_coding_gene CG14428 IPR027858=Protein of unknown function DUF4516 CG42308 16-Dec-15 2015_12 ENSDARG00000045797(gb:cn833218) ENSMUSG00000063320(1190007I07Rik) FBgn0033199 CG17985 http://flybase.net/reports/FBgn0033199.html protein_coding_gene IPR018392=LysM domain CG17985 16-Dec-15 2015_12 "ENSDARG00000024693(lysmd3),ENSDARG00000039058,ENSDARG00000068702(zgc:77861)" "ENSXETG00000018786(LYSMD4),ENSXETG00000019627(TEgg001d10.1)" "ENSMUSG00000035840(Lysmd3),ENSMUSG00000043831(Lysmd4)" "ENSG00000183060(LYSMD4),ENSG00000176018(LYSMD3)" "partially lethal - majority die,some die during pupal stage" FBgn0026316 Ubc10 Ubiquitin conjugating enzyme 10 http://flybase.net/reports/FBgn0026316.html FBgn0028742 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0031625=ubiquitin protein ligase binding, 0005515=protein binding" "0016567=protein ubiquitination, 0022008=neurogenesis" "UbcD10, EG:52C10.4, CG5788, ubc, ubcD10" "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG5788 16-Dec-15 2015_12 "ENSDARG00000019188(ube2l3),ENSDARG00000027141(ube2l3l)" WBGene00006713(ubc-18) ENSXETG00000022422(ube2l3) "ENSMUSG00000038965(Ube2l3),ENSMUSG00000064208(Gm10145)" ENSG00000185651(UBE2L3) "neuroanatomy defective,somatic clone,viable,fertile,lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "neuroblast,somatic clone,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC07568 E 0.07364313 -0.261077441 2.204031409 0.537881657 0.254657061 0.541279726 FBgn0053815 His3:CG33815 His3:CG33815 http://flybase.net/reports/FBgn0053815.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33815 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33815 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0035085 CG3770 http://flybase.net/reports/FBgn0035085.html protein_coding_gene "0007163=establishment or maintenance of cell polarity, 0060857=establishment of glial blood-brain barrier" 0005918=septate junction CT12588 IPR019372=Lipoma HMGIC fusion partner-like protein CG3770 16-Dec-15 2015_12 "ENSDARG00000071509(LOC100148206),ENSDARG00000039926(lhfpl2),ENSDARG00000009653(zgc:77456)" ENSXETG00000000546(LHFPL2) ENSMUSG00000045312(Lhfpl2) ENSG00000145685(LHFPL2) viable FBgn0051626 CG31626 http://flybase.net/reports/FBgn0051626.html FBgn0063685 protein_coding_gene BcDNA:RE20756 IPR004019=YLP motif CG31626 16-Dec-15 2015_12 "ENSXETG00000015080(),ENSXETG00000015480(),ENSXETG00000001378(),ENSXETG00000003613(),ENSXETG00000013355(),ENSXETG00000006375(),ENSXETG00000013595(),ENSXETG00000021278(),ENSXETG00000014082(),ENSXETG00000025634(),ENSXETG00000012800(),ENSXETG00000014412(),ENSXETG00000022340(),ENSXETG00000013141()" FBgn0038837 CG3822 http://flybase.net/reports/FBgn0038837.html protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0015277=kainate selective glutamate receptor activity" "0060025=regulation of synaptic activity, 0006811=ion transport" 0005886=plasma membrane "DKaiRID, DmelCG3822, CT12759" "IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR028082=Periplasmic binding protein-like I, IPR001828=Receptor, ligand binding region, IPR001508=Ionotropic glutamate receptor, metazoa" CG3822 16-Dec-15 2015_12 ENSDARG00000040627(LOC561540) WBGene00001616(glr-5) ENSXETG00000017031(GRIK4) "ENSMUSG00000056073(Grik2),ENSMUSG00000001985(Grik3),ENSMUSG00000022935(Grik1)" "ENSG00000164418(GRIK2),ENSG00000163873(GRIK3),ENSG00000171189(GRIK1)" "viable,fertile" FBgn0015271 Orc5 Origin recognition complex subunit 5 http://flybase.net/reports/FBgn0015271.html FBgn0001963 protein_coding_gene 0003677=DNA binding "0006260=DNA replication, 0007052=mitotic spindle organization, 0007076=mitotic chromosome condensation, 0006342=chromatin silencing, 0046331=lateral inhibition, 0006270=DNA replication initiation, 0006261=DNA-dependent DNA replication" 0005664=nuclear origin of replication recognition complex "l(2)br39, l(2)34Df, D-orc5, DmORC5, ORC, lethal(2)34Df, BG:DS00941.8, CG7833, orc5, ORC5, br39, DmOrc5, dORC5" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020796=Origin recognition complex, subunit 5, IPR003593=AAA+ ATPase domain" CG7833 16-Dec-15 2015_12 ENSDARG00000021579(orc5l) YNL261W(ORC5) WBGene00013857(ZC168.3) ENSXETG00000015946(ORC5L) ENSMUSG00000029012(Orc5l) ENSG00000164815(ORC5) embryonic stage && larval stage "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" "mitotic cell cycle,mitosis & nuclear chromosome,chromosome, centromeric region,imaginal disc,spindle,mitotic metaphase,follicle cell,mitotic metaphaseb84a9),mitosis & nuclear chromosomeb84a9),chaeta,trichogen cell" FBgn0053870 His2B:CG33870 His2B:CG33870 http://flybase.net/reports/FBgn0053870.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33870 "IPR009072=Histone-fold, IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3" CG33870 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053513 Nmdar2 NMDA receptor 2 http://flybase.net/reports/FBgn0053513.html "FBgn0014432, FBgn0044503" protein_coding_gene "0005234=extracellular-glutamate-gated ion channel activity, 0004972=N-methyl-D-aspartate selective glutamate receptor activity" "0007616=long-term memory, 0072375=medium-term memory, 0006811=ion transport, 0050975=sensory perception of touch, 0035235=ionotropic glutamate receptor signaling pathway" "0008328=ionotropic glutamate receptor complex, 0016021=integral component of membrane" "CG14794, NMDA receptor 2, NR2, CT34603, ESTS:79G8T, EG:80H7.7, dsNR2, DrNR2, NMDA receptor, anon-sts34, DmelNmdar2, CG14793, 79G8T, dnmdar-II, CG33513, NMDAR2, dNR2" "IPR028082=Periplasmic binding protein-like I, IPR001320=Ionotropic glutamate receptor, IPR019594=Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001508=Ionotropic glutamate receptor, metazoa, IPR001828=Receptor, ligand binding region" CG33513 16-Dec-15 2015_12 "ENSDARG00000034493(LOC563297),ENSDARG00000070543(grin2ab),ENSDARG00000030376(LOC559976),ENSDARG00000070620,ENSDARG00000058441(si:dkey-154b17.1)" WBGene00003775(nmr-2) "ENSXETG00000006844(GRIN2C),ENSXETG00000010593(GRIN2D),ENSXETG00000008002(GRIN2A)" "ENSMUSG00000030209(Grin2b),ENSMUSG00000059003(Grin2a),ENSMUSG00000020734(Grin2c),ENSMUSG00000002771(Grin2d)" "ENSG00000150086(GRIN2B),ENSG00000183454(GRIN2A),ENSG00000161509(GRIN2C),ENSG00000105464(GRIN2D)" "memory defective,viable,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,touch sensitivity defective" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0029941 CG1677 http://flybase.net/reports/FBgn0029941.html protein_coding_gene 0046872=metal ion binding "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005634=nucleus, 0071013=catalytic step 2 spliceosome" "IPR000571=Zinc finger, CCCH-type" CG1677 16-Dec-15 2015_12 ENSDARG00000062506(si:ch211-218c6.1) ENSMUSG00000017478(Zc3h18) ENSG00000158545(ZC3H18) "viable,fertile,female fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female semi-fertile" embryonic/larval neuroblast DRSC18116 I 2.126773905 -0.438586079 0.170115823 -0.091099239 0.461232215 -0.144824667 FBgn0028482 bdl borderless http://flybase.net/reports/FBgn0028482.html protein_coding_gene 0098632=protein binding involved in cell-cell adhesion "0007155=cell adhesion, 0007158=neuron cell-cell adhesion, 0045467=R7 cell development, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" 0005887=integral component of plasma membrane "GH11322, CG16857, BcDNA:GH11322, CT35491" "IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013106=Immunoglobulin V-set domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III" CG16857 16-Dec-15 2015_12 viable DRSC00271 K -0.757243513 0.24895887 0.052018036 -0.041024236 -0.132413173 2.121578158 FBgn0031888 Pvf2 PDGF- and VEGF-related factor 2 http://flybase.net/reports/FBgn0031888.html protein_coding_gene "0008083=growth factor activity, 0005172=vascular endothelial growth factor receptor binding" "0035099=hemocyte migration, 0007435=salivary gland morphogenesis, 0035172=hemocyte proliferation, 0048010=vascular endothelial growth factor receptor signaling pathway" 0016020=membrane "Vegf27Cb, PDGF- and VEGF-receptor related factor 2, CG13780, DmVEGF-2, VEGF-related factor 2, PV2, Pvf, VEGF27Cb, PVFs, VEGF, PVF, VEGF-2, PVF2, pvf2" "IPR000072=PDGF/VEGF domain, IPR029034=Cystine-knot cytokine" CG13780 16-Dec-15 2015_12 " embryonic stage | stage 9-15 , embryonic stage | stage 9-11 , embryonic stage | stage 11-13 " " embryonic foregut

, embryonic hindgut

, Malpighian tubule

, posterior ectoderm

restricted , ventral nerve cord

" "viable,lethal,partially,some die during pupal stage,lethal - all die before end of pupal stage" "embryonic hemocyte,adult midgut,ventral nerve cord | embryonic stage,hemocyte,intestinal stem cell,enteroendocrine cell,supernumerary,enterocyte,embryonic/larval hemocyte,crystal cell,plasmatocyte" DRSC02283 K -0.279636555 0.173661761 -0.264803984 0.486477651 1.79118557 1.900943728 FBgn0034392 MFS15 Major Facilitator Superfamily Transporter 15 http://flybase.net/reports/FBgn0034392.html protein_coding_gene 0005316=high-affinity inorganic phosphate:sodium symporter activity "0006817=phosphate ion transport, 0055085=transmembrane transport, 0006814=sodium ion transport" 0016021=integral component of membrane CG15094 "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG15094 16-Dec-15 2015_12 "YGR260W(TNA1),YIL166C()" "viable,fertile" DRSC06523 I 2.207208185 0.138417628 -0.349999498 0.070766584 0.418157363 0.270200772 FBgn0038934 Gld2 http://flybase.net/reports/FBgn0038934.html protein_coding_gene 0004652=polynucleotide adenylyltransferase activity "0043631=RNA polyadenylation, 0007616=long-term memory" "0005737=cytoplasm, 0043005=neuron projection, 0005654=nucleoplasm" "DmCG5732, DmGLD2, CG5732, Dm1" IPR002058=PAP/25A-associated CG5732 16-Dec-15 2015_12 "ENSDARG00000055385(LOC100333585),ENSDARG00000071511(papd4)" "YOL115W(PAP2),YNL299W(TRF5)" WBGene00001596(gld-2) ENSMUSG00000042167(Papd4) ENSG00000164329(PAPD4) "memory defective,heat sensitive" DRSC23037 K -1.500219939 -0.219348702 FBgn0031548 CG8852 http://flybase.net/reports/FBgn0031548.html protein_coding_gene CT9284 IPR001611=Leucine-rich repeat CG8852 16-Dec-15 2015_12 viable DRSC00719 K -0.26838558 0.093346444 -0.171114927 1.091080398 -0.39715126 -2.382565628 FBgn0031633 Fnta Farnesyl transferase ë± http://flybase.net/reports/FBgn0031633.html protein_coding_gene 0004660=protein farnesyltransferase activity "0018342=protein prenylation, 0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction" 0005965=protein farnesyltransferase complex "FNTA, Farnesyl transferase alpha ortholog, CG2976, farnesyl transferase alpha" "IPR002088=Protein prenyltransferase, alpha subunit" CG2976 16-Dec-15 2015_12 ENSDARG00000037665(fnta) YKL019W(RAM2) WBGene00019823(fnta-1) ENSXETG00000004459(FNTA) ENSMUSG00000015994(Fnta) ENSG00000168522(FNTA) "planar polarity defective,viable,visible" "wing | pupal stage,wing hair | pupal stage,mesothoracic tergum" DRSC00557 K -0.713231025 0.564055174 -0.305507899 0.006719208 -0.341854177 -4.007806652 FBgn0037665 St2 Sulfotransferase 2 http://flybase.net/reports/FBgn0037665.html protein_coding_gene 0008146=sulfotransferase activity 0051923=sulfation 0005829=cytosol "st2, dmST2, CG16733" "IPR000863=Sulfotransferase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG16733 16-Dec-15 2015_12 "ENSDARG00000018361(LOC100332243),ENSDARG00000041540(sult1st2),ENSDARG00000028275(sult1st1),ENSDARG00000003181(sult1st4),ENSDARG00000006811(sult1st6),ENSDARG00000003475" WBGene00013748(ssu-1) "ENSXETG00000009267(BC075315.1),ENSXETG00000009265(BC074610.1),ENSXETG00000008329(),ENSXETG00000020702(),ENSXETG00000027944(),ENSXETG00000010785()" "ENSMUSG00000018865(Sult4a1),ENSMUSG00000030711(Sult1a1)" "ENSG00000130540(SULT4A1),ENSG00000109193(SULT1E1)" viable DRSC15142 I -1.652370583 1.144830947 0.952527013 0.628066 0.720347699 0.023607367 FBgn0262717 Skeletor Skeletor http://flybase.net/reports/FBgn0262717.html "FBgn0020517, FBgn0037821, FBgn0051261, FBgn0052922, FBgn0053676, FBgn0037820" protein_coding_gene "0005198=structural molecule activity, 0004500=dopamine beta-monooxygenase activity" "0051225=spindle assembly, 0006997=nucleus organization, 0006584=catecholamine metabolic process" "0016363=nuclear matrix, 0005652=nuclear lamina, 0005700=polytene chromosome, 0005819=spindle, 0005634=nucleus, 0005694=chromosome" "2Ab3, CG33676, CG14682, CG32922, CG43161, unnamed, skeletor, CG14681, CG31261, Skeletor" "IPR005018=DOMON domain, IPR019545=DM13 domain" CG43161 16-Dec-15 2015_12 WBGene00020921(W01C8.5) "viable,fertile" DRSC14906 E 0.382358452 0.293228588 2.163849219 0.83989019 0.709770824 0.158319716 FBgn0039777 Jon99Fii Jonah 99Fii http://flybase.net/reports/FBgn0039777.html FBgn0001289 protein_coding_gene "0004252=serine-type endopeptidase activity, 0004175=endopeptidase activity" 0006508=proteolysis "Jonah 99F, Jon99F, CG2229, SP135" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG2229 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0033391 CG8026 http://flybase.net/reports/FBgn0033391.html "FBgn0063441, FBgn0063442, FBgn0063443" protein_coding_gene "0008517=folic acid transporter activity, 0022857=transmembrane transporter activity" "0055085=transmembrane transport, 0006839=mitochondrial transport, 0015884=folic acid transport" "0005743=mitochondrial inner membrane, 0031966=mitochondrial membrane" "anon-WO0242455.53, anon-WO0242455.7, Dromel_CG8026_FBtr0088611_mORF, anon-WO0242455.6" "IPR023395=Mitochondrial carrier domain, IPR002067=Mitochondrial carrier protein, IPR018108=Mitochondrial substrate/solute carrier" CG8026 16-Dec-15 2015_12 "ENSDARG00000056217,ENSDARG00000026835(slc25a32b)" YIL134W(FLX1) WBGene00010459(K01C8.7) ENSXETG00000004096(SLC25A32) ENSMUSG00000022299(Slc25a32) ENSG00000164933(SLC25A32) viable FBgn0033122 CG17002 http://flybase.net/reports/FBgn0033122.html protein_coding_gene IPR026094=G protein pathway suppressor 2 CG17002 16-Dec-15 2015_12 ENSDARG00000035558(gps2) ENSMUSG00000023170(Gps2) ENSG00000132522(GPS2) "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0043791 CG8147 http://flybase.net/reports/FBgn0043791.html "FBgn0037699, FBtr0082060, FBpp0081538" protein_coding_gene 0004035=alkaline phosphatase activity "0016311=dephosphorylation, 0035094=response to nicotine" 0009986=cell surface "154821_at, BEST:LD38109" "IPR018299=Alkaline phosphatase, active site, IPR017850=Alkaline-phosphatase-like, core domain, IPR001952=Alkaline phosphatase, IPR017849=Alkaline phosphatase-like, alpha/beta/alpha" CG8147 16-Dec-15 2015_12 "ENSDARG00000015546(alp),ENSDARG00000039048,ENSDARG00000015273(alpi),ENSDARG00000053774(zgc:110409)" YDR481C(PHO8) "ENSXETG00000023244(ALPL),ENSXETG00000022768(BC089726.1)" "ENSMUSG00000028766(Alpl),ENSMUSG00000026246(Alppl2),ENSMUSG00000079440(Alpi),ENSMUSG00000036500(Akp3)" "ENSG00000162551(ALPL),ENSG00000163295(ALPI),ENSG00000163286(ALPPL2),ENSG00000163283(ALPP)" viable FBgn0264693 ens ensconsin http://flybase.net/reports/FBgn0264693.html "FBgn0035500, FBgn0086232" protein_coding_gene 0008017=microtubule binding "0046785=microtubule polymerization, 0051299=centrosome separation, 2000574=regulation of microtubule motor activity, 0031987=locomotion involved in locomotory behavior, 0048741=skeletal muscle fiber development, 0060632=regulation of microtubule-based movement, 0040023=establishment of nucleus localization" "0045177=apical part of cell, 0015630=microtubule cytoskeleton" "swoosh, Dm-308, ensc, CG14998" IPR008604=Microtubule-associated protein 7 family CG14998 16-Dec-15 2015_12 "ENSDARG00000060771(LOC794500),ENSDARG00000060341,ENSDARG00000060304,ENSDARG00000062543(zgc:172238),ENSDARG00000045316" FBgn0028996 onecut onecut http://flybase.net/reports/FBgn0028996.html FBgn0039913 protein_coding_gene "0003677=DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0006351=transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG1922, D-onecut, A1" "IPR001356=Homeobox domain, IPR010982=Lambda repressor-like, DNA-binding domain, IPR009057=Homeodomain-like, IPR003350=CUT domain" CG1922 16-Dec-15 2015_12 "ENSDARG00000056395(LOC565854),ENSDARG00000045300,ENSDARG00000007982(onecut1),ENSDARG00000040253(onecutl)" WBGene00015934(ceh-48) "ENSXETG00000008911(ONECUT3),ENSXETG00000006349(ONECUT1)" "viable,fertile,lethal,recessive,partially lethal - majority die,some die during pupal stage" FBgn0039835 mRpL32 mitochondrial ribosomal protein L32 http://flybase.net/reports/FBgn0039835.html FBgn0063139 protein_coding_gene 0003735=structural constituent of ribosome 0006412=translation 0005762=mitochondrial large ribosomal subunit "BcDNA:LD41522, RpL32, CG12220, L32" IPR011332=Zinc-binding ribosomal protein CG12220 16-Dec-15 2015_12 ENSDARG00000060489(zgc:153328) YCR003W(MRPL32) WBGene00016249(C30C11.1) ENSXETG00000001852(MRPL32) "ENSMUSG00000015672(Mrpl32),ENSMUSG00000057223" ENSG00000106591(MRPL32) "viable,visible" trichogen cell DRSC14479 IE -0.17296944 2.25137822 -1.523178217 -0.117618292 -0.647544798 -0.47835507 FBgn0038586 CG7168 http://flybase.net/reports/FBgn0038586.html protein_coding_gene "IPR017920=COMM domain, IPR009886=HCaRG" CG7168 16-Dec-15 2015_12 ENSDARG00000003373(commd2) ENSXETG00000016010(COMMD2) ENSMUSG00000036513(Commd2) ENSG00000114744(COMMD2) viable FBgn0038381 CG3303 http://flybase.net/reports/FBgn0038381.html protein_coding_gene "0004252=serine-type endopeptidase activity, 0016788=hydrolase activity, acting on ester bonds" IPR018998=Endoribonuclease XendoU CG3303 16-Dec-15 2015_12 "ENSDARG00000058366(si:dkey-222f8.3),ENSDARG00000008915(LOC100329620),ENSDARG00000020122(zgc:110053)" WBGene00010488(K02A11.3) ENSXETG00000016505() ENSMUSG00000022468(Endou) ENSG00000111405(ENDOU) viable FBgn0023197 Jon74E Jonah 74E http://flybase.net/reports/FBgn0023197.html FBgn0036737 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "CG6298, CT19724, SP85, unnamed" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG6298 16-Dec-15 2015_12 "ENSDARG00000016538(zgc:55888),ENSDARG00000028780(LOC795070)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" FBgn0033302 Cyp6a14 Cyp6a14 http://flybase.net/reports/FBgn0033302.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding" 0055114=oxidation-reduction process 0043231=intracellular membrane-bounded organelle "cytochrome P450, 6a14, CG8687" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG8687 16-Dec-15 2015_12 ENSDARG00000002249(LOC100331448) YHR007C(ERG11) "WBGene00014697(cyp-25A3),WBGene00007964(cyp-25A2),WBGene00007963(cyp-25A1),WBGene00007967(cyp-25A4),WBGene00018326(cyp-25A5)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" FBgn0035189 CG9119 http://flybase.net/reports/FBgn0035189.html protein_coding_gene "0016788=hydrolase activity, acting on ester bonds, 0008270=zinc ion binding" 0005634=nucleus CT9987 IPR015021=Domain of unknown function DUF1907 CG9119 16-Dec-15 2015_12 ENSDARG00000016655(zgc:85789) WBGene00016046(C24B5.4) ENSXETG00000018450(TEgg069a24.1) ENSMUSG00000031938(4931406C07Rik) ENSG00000182919(C11orf54) viable FBgn0040256 Ugt86Dd Ugt86Dd http://flybase.net/reports/FBgn0040256.html FBgn0037861 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG6633, AC 006491D" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG6633 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00010904(ugt-62),WBGene00018206(ugt-61)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0053857 His3:CG33857 His3:CG33857 http://flybase.net/reports/FBgn0053857.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33857 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG33857 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0040251 Ugt86Di Ugt86Di http://flybase.net/reports/FBgn0040251.html FBgn0037863 protein_coding_gene 0015020=glucuronosyltransferase activity 0008152=metabolic process "CG6658, AC 006491I" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG6658 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable FBgn0053910 His2B:CG33910 His2B:CG33910 http://flybase.net/reports/FBgn0053910.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33910 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000558=Histone H2B" CG33910 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0031619 CG3355 http://flybase.net/reports/FBgn0031619.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP21 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG3355 16-Dec-15 2015_12 "ENSDARG00000056324(zgc:123295),ENSDARG00000046140(zgc:112038),ENSDARG00000055644(zgc:101788),ENSDARG00000070713(zgc:162180),ENSDARG00000070710(wu:fk80d04),ENSDARG00000061858(zgc:153968),ENSDARG00000056773(zgc:163079),ENSDARG00000052064(LOC571079),ENSDARG00000063444,ENSDARG00000070518,ENSDARG00000019714" WBGene00006619(try-1) "ENSXETG00000017962(),ENSXETG00000016040(TMPRSS6),ENSXETG00000027846(),ENSXETG00000015131(),ENSXETG00000016870(HPN),ENSXETG00000027104(),ENSXETG00000010125(TMPRSS13),ENSXETG00000007294(TMPRSS12)" "ENSMUSG00000024034(Tmprss3),ENSMUSG00000000385(Tmprss2),ENSMUSG00000032268(Tmprss5),ENSMUSG00000001249(Hpn)" viable FBgn0036374 Spt20 Spt20 http://flybase.net/reports/FBgn0036374.html protein_coding_gene 0003712=transcription cofactor activity 0016573=histone acetylation "0000124=SAGA complex, 0070461=SAGA-type complex, 0005634=nucleus" "CG17689, Spt20, lincRNA.S5070" IPR021950=Transcription factor Spt20 CG17689 16-Dec-15 2015_12 DRSC25791 K 0.752675837 1.67752533 FBgn0035006 CG4563 http://flybase.net/reports/FBgn0035006.html protein_coding_gene 0016207=4-coumarate-CoA ligase activity 0008152=metabolic process "IPR000873=AMP-dependent synthetase/ligase, IPR025110=AMP-binding enzyme C-terminal domain" CG4563 16-Dec-15 2015_12 "partially lethal - majority die,some die during pupal stage" DRSC04474 K 1.094311827 -0.061981309 -0.530343507 0.160483336 -0.178957442 -1.96848261 FBgn0032705 Grip71 Grip71 http://flybase.net/reports/FBgn0032705.html protein_coding_gene 0043015=gamma-tubulin binding "0051298=centrosome duplication, 0051297=centrosome organization, 0051726=regulation of cell cycle, 0007057=spindle assembly involved in female meiosis I, 0090307=mitotic spindle assembly, 0007067=mitotic nuclear division, 0007052=mitotic spindle organization, 0045450=bicoid mRNA localization" "0008274=gamma-tubulin ring complex, 0005737=cytoplasm" "Dgp71WD, Dgrip71, Grip71wd, CG10346" "IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG10346 16-Dec-15 2015_12 "viable,female sterile,male fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,mitotic cell cycle defective" "meiotic spindleED119),S2 cell-line,spindle,neuroblast" DRSC02042 IE 2.396538247 1.170734939 2.04178651 0.545331882 -0.677153768 -1.39127762 FBgn0262517 Ltn1 Listerin E3 ubiquitin protein ligase 1 http://flybase.net/reports/FBgn0262517.html "FBgn0084292, FBgn0052210, FBgn0036883, FBgn0036885" protein_coding_gene 0008270=zinc ion binding 1990116=ribosome-associated ubiquitin-dependent protein catabolic process "CG32210, CG9274, l(3)76BDr, CG9268" "IPR016024=Armadillo-type fold, IPR001841=Zinc finger, RING-type, IPR011989=Armadillo-like helical, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG32210 16-Dec-15 2015_12 YMR247C(RKR1) WBGene00021831(Y54E10A.11) ENSMUSG00000052299(Rnf160) ENSG00000198862(LTN1) DRSC11056 IE 1.576156961 0.148107878 1.563090841 -0.508509457 -0.195393408 -0.132806523 FBgn0004655 wapl wings apart-like http://flybase.net/reports/FBgn0004655.html "FBgn0001396, FBgn0004001" protein_coding_gene "0007062=sister chromatid cohesion, 0016321=female meiosis chromosome segregation" "0005634=nucleus, 0005700=polytene chromosome" "Wapl, l(1)N5[72], RNAD, l(1)C204, l(1)2Dd, l(1)2Df, C204, EG:87B1.2, wap, N2, l(1)N2, wings-apart-like, parallel sister chromatids protein, l74, RNA D, CG3707, pasc" "IPR011989=Armadillo-like helical, IPR022771=Wings apart-like protein, IPR012502=Wings apart-like, metazoan/plants, IPR016024=Armadillo-type fold" CG3707 16-Dec-15 2015_12 ENSDARG00000044144(kiaa0261) ENSMUSG00000041408(Wapal) ENSG00000062650(WAPAL) embryonic stage "lethal,recessive,some die during second instar larval stage,partially lethal - majority die,visible,suppressor of variegation,dominant,non-suppressor of variegation,non-enhancer of variegation,enhancer of variegation,germline clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective" "tergite,wing vein,eye,wing,pre-blastoderm embryo,germline clone,maternal effect,heterochromatin | maternal effect,metaphase & condensed nuclear chromosome | maternal effect,sex comb,ectopic,adult abdomen,posterior,sternopleural bristle,male genitalia" DRSC27941 K -0.157093315 1.062571687 -0.104295441 0.545147092 -0.031255945 2.025374172 FBgn0034165 CG6435 http://flybase.net/reports/FBgn0034165.html protein_coding_gene 0003796=lysozyme activity "IPR008597=Destabilase, IPR023346=Lysozyme-like domain" CG6435 16-Dec-15 2015_12 "WBGene00017691(ilys-5),WBGene00016670(ilys-3),WBGene00016669(ilys-2),WBGene00016668(ilys-1),WBGene00016958(ilys-4)" viable DRSC06987 E -0.199253084 0.573510965 1.771714389 0.607539304 -0.440522651 -0.372546919 FBgn0035915 S-Lap1 Sperm-Leucylaminopeptidase 1 http://flybase.net/reports/FBgn0035915.html FBgn0044537 protein_coding_gene "0030145=manganese ion binding, 0004177=aminopeptidase activity, 0008235=metalloexopeptidase activity" "0016319=mushroom body development, 0006508=proteolysis" 0005737=cytoplasm "S-LAP 1, Sperm-LeucylAminoPeptidase 1, CG6372, bs33g03.y1, bs34e01.y1, anon-WO0140519.89" "IPR011356=Leucine aminopeptidase/peptidase B, IPR000819=Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283=Peptidase M17, leucyl aminopeptidase, N-terminal" CG6372 16-Dec-15 2015_12 ENSDARG00000061981(lap3) ENSXETG00000020343(lap3) ENSMUSG00000039682(Lap3) ENSG00000002549(LAP3) neuroanatomy defective adult mushroom body DRSC10627 K 0.105527723 -0.420773433 0.093738646 -0.205905885 -1.515295161 -0.717908564 FBgn0264908 pHCl http://flybase.net/reports/FBgn0264908.html "FBgn0036542, FBgn0036543, FBgn0046788, FBgn0053989, FBgn0082882, FBtr0075531, FBpp0075286, FBtr0075532, FBpp0075287, FBgn0036541" protein_coding_gene "0005254=chloride channel activity, 0016934=extracellular-glycine-gated chloride channel activity" "0006811=ion transport, 0022008=neurogenesis" 0016935=glycine-gated chloride channel complex "CT19189, CG12486, CG13444, unnamed, pHCL-A, CG6112, BP1024, pHCl, CG33989, CG44099, BcDNA:GH21757, glutamate-gated chloride channel-like" "IPR006029=Neurotransmitter-gated ion-channel transmembrane domain, IPR006201=Neurotransmitter-gated ion-channel, IPR006202=Neurotransmitter-gated ion-channel ligand-binding domain, IPR006028=Gamma-aminobutyric acid A receptor/Glycine receptor alpha" CG44099 16-Dec-15 2015_12 DRSC09991 I 1.519967521 0.095913365 0.008321837 -0.370159769 -0.540510463 0.300037569 FBgn0053896 His2B:CG33896 His2B:CG33896 http://flybase.net/reports/FBgn0053896.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33896 "IPR000558=Histone H2B, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33896 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0034051 Mlf Myelodysplasia/myeloid leukemia factor http://flybase.net/reports/FBgn0034051.html FBgn0064773 protein_coding_gene "2000495=regulation of cell proliferation involved in compound eye morphogenesis, 0006355=regulation of transcription, DNA-templated, 0050821=protein stabilization" "0005634=nucleus, 0005705=polytene chromosome interband, 0005737=cytoplasm, 0048471=perinuclear region of cytoplasm" "MLF, dmlf, dMLF, CG8295, myeloid leukemia factor, Drosophila Myeloid Leukemia Factor, Myeloid leukemia factor, mlf, BcDNA:SD18148" IPR019376=Myeloid leukemia factor CG8295 16-Dec-15 2015_12 ENSDARG00000034616(zgc:114097) WBGene00012468(Y17G7B.17) ENSXETG00000011538(mlf2) "ENSMUSG00000030120(Mlf2),ENSMUSG00000048416(Mlf1)" "ENSG00000089693(MLF2),ENSG00000178053(MLF1)" "wild-type,visible,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,lethal,heat sensitive,increased cell death,melanotic necrosis,eye color defective" "interocellar bristle,head bristle,wing vein,ectopic,crystal cell,2nd posterior cell,anterior crossvein,scutellar bristle,wing margin,wing,posterior compartment,wing disc,ommatidium,interommatidial bristle,eye,pigment cell" DRSC07472 IEK 4.204039884 3.75936023 8.161599187 -1.083441085 -0.674976756 1.542831348 FBgn0052533 CG32533 http://flybase.net/reports/FBgn0052533.html "FBgn0031017, FBgn0031019" protein_coding_gene "0004386=helicase activity, 0004004=ATP-dependent RNA helicase activity" "0000398=mRNA splicing, via spliceosome" 0005634=nucleus "cg12211, CG14198, CG12211" "IPR011709=Domain of unknown function DUF1605, IPR007502=Helicase-associated domain, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal" CG32533 16-Dec-15 2015_12 ENSDARG00000061168(si:ch211-255l12.1) WBGene00021365(smgl-2) ENSXETG00000012176(DHX34) ENSMUSG00000006019(Dhx34) ENSG00000134815(DHX34) "viable,fertile" FBgn0040028 CG17450 http://flybase.net/reports/FBgn0040028.html protein_coding_gene 0046692=sperm competition tektin IPR000435=Tektin CG17450 16-Dec-15 2015_12 ENSDARG00000045038(tekt3) WBGene00019828(R02E12.4) ENSXETG00000019577(tekt3) "ENSMUSG00000042189(Tekt3),ENSMUSG00000039179(Tekt5)" "ENSG00000125409(TEKT3),ENSG00000153060(TEKT5)" FBgn0035065 CG3589 http://flybase.net/reports/FBgn0035065.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005777=peroxisome "IPR009003=Peptidase S1, PA clan" CG3589 16-Dec-15 2015_12 ENSXETG00000006146(TYSND1) ENSMUSG00000020087(Tysnd1) ENSG00000156521(TYSND1) "viable,fertile" FBgn0039732 CG15525 http://flybase.net/reports/FBgn0039732.html FBgn0062853 protein_coding_gene 0005515=protein binding BcDNA:SD23244 "IPR013169=mRNA splicing factor, Cwf18" CG15525 16-Dec-15 2015_12 ENSDARG00000023003(ccdc12) WBGene00022092(Y69A2AR.21) ENSXETG00000013123(CCDC12) ENSMUSG00000019659(Ccdc12) ENSG00000160799(CCDC12) DRSC15062 K -0.447038015 1.459494306 0.444748263 -0.116245676 -2.144548309 0.297137624 FBgn0040340 TRAM TRAM http://flybase.net/reports/FBgn0040340.html "FBgn0029545, FBgn0042153" protein_coding_gene "0006909=phagocytosis, 0006614=SRP-dependent cotranslational protein targeting to membrane" "0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005811=lipid particle" "EG:BACR7A4.5, CG11642, CG18830" "IPR013599=TRAM1-like protein, IPR016447=Translocation associated membrane protein, IPR006634=TRAM/LAG1/CLN8 homology domain" CG11642 16-Dec-15 2015_12 "ENSDARG00000019137(tram1),ENSDARG00000037813(zgc:113278),ENSDARG00000030092" WBGene00007696(tram-1) "ENSXETG00000015948(tram1),ENSXETG00000000663(TRAM2)" "ENSMUSG00000025935(Tram1),ENSMUSG00000044528(Tram1l1),ENSMUSG00000041779(Tram2)" "ENSG00000067167(TRAM1),ENSG00000174599(TRAM1L1),ENSG00000065308(TRAM2)" viable FBgn0010225 Gel Gelsolin http://flybase.net/reports/FBgn0010225.html "FBan0001106, FBgn0037221" protein_coding_gene "0005509=calcium ion binding, 0003779=actin binding" "0051016=barbed-end actin filament capping, 0045010=actin nucleation, 0051014=actin filament severing, 0030041=actin filament polymerization, 0006909=phagocytosis" "0005884=actin filament, 0005829=cytosol, 0005576=extracellular region" "gelsolin, DGS, gel, Drosophila Gelsolin, CG1106" "IPR029006=ADF-H/Gelsolin-like domain, IPR007123=Gelsolin-like domain, IPR030004=Gelsolin, IPR007122=Villin/Gelsolin" CG1106 16-Dec-15 2015_12 "ENSDARG00000011459(gsna),ENSDARG00000045262(gsnb),ENSDARG00000069983(scinla),ENSDARG00000010728(scin),ENSDARG00000058348(scinlb),ENSDARG00000059342(zgc:136857),ENSDARG00000001909(LOC555361),ENSDARG00000040466(vil1l)" "ENSXETG00000011333(),ENSXETG00000019813(gsn),ENSXETG00000009647(AVIL),ENSXETG00000018470(vil1),ENSXETG00000014965(VIL1)" "ENSMUSG00000026879(Gsn),ENSMUSG00000002565(Scin),ENSMUSG00000026175(Vil1),ENSMUSG00000025432(Avil)" "ENSG00000148180(GSN),ENSG00000006747(SCIN),ENSG00000127831(VIL1),ENSG00000135407(AVIL)" "partially lethal - majority die,some die during pupal stage" "adult brain,mitochondrionelav.PU" FBgn0005695 gcl germ cell-less http://flybase.net/reports/FBgn0005695.html FBgn0004886 protein_coding_gene "0007278=pole cell fate determination, 0007281=germ cell development, 0016480=negative regulation of transcription from RNA polymerase III promoter, 0007315=pole plasm assembly, 0007279=pole cell formation, 0045892=negative regulation of transcription, DNA-templated" "0005634=nucleus, 0045495=pole plasm, 0034399=nuclear periphery, 0005643=nuclear pore, 0005938=cell cortex" "GCL, germ cell less, CG8411, Gcl, germ-cell-less, gcl-1" "IPR000210=BTB/POZ domain, IPR011333=POZ domain" CG8411 16-Dec-15 2015_12 ENSDARG00000020948(gmcl1) WBGene00013382(gcl-1) ENSXETG00000008208(GMCL1) "ENSMUSG00000001157(Gmcl1),ENSMUSG00000078216(Gm10922),ENSMUSG00000078209(Gm14374),ENSMUSG00000078221(Gm14345),ENSMUSG00000078222(Gm14346),ENSMUSG00000078220(Gm14351),ENSMUSG00000078326(Gm2913),ENSMUSG00000078330(Gm2825),ENSMUSG00000078333(Gm2799),ENSMUSG00000078217(Gm14347),ENSMUSG00000078323(Gm2964),ENSMUSG00000078219(Gm3701),ENSMUSG00000078336(Gm2777),ENSMUSG00000078215(Gm10921),ENSMUSG00000078332(Gmcl1l),ENSMUSG00000078324(Gm2933),ENSMUSG00000078325(Gm2927),ENSMUSG00000078335(Gm2784),ENSMUSG00000078211(Gm3763),ENSMUSG00000078213(Gm3750),ENSMUSG00000078218(Gm3706)" ENSG00000087338(GMCL1) " embryonic stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >S11 , embryonic stage | early , adult stage && oogenesis stage | stage S8-10 , adult stage && oogenesis stage | stage S10 " " embryonic/larval foregut

, ovary

, oocyte | posterior

, embryonic/larval hindgut

, pole cell

, nurse cell

, embryonic central nervous system | restricted

, larval muscle system

, oocyte

" embryonic stage pole cell

"viable,fertile,wild-type,sterile,female semi-sterile,maternal effect,meiotic cell cycle defective,decreased cell number" "pole cell,ectopic,pole bud & nucleus,maternal effect,pole bud,germline cell" DRSC07623 E 0.41098917 -0.116359899 -1.762472348 -0.332160813 -0.235853333 0.286612685 FBgn0020304 drongo drongo http://flybase.net/reports/FBgn0020304.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity CG3365 IPR001164=Arf GTPase activating protein CG3365 16-Dec-15 2015_12 "ENSDARG00000019526(agfg1b),ENSDARG00000030020(agfg1a)" ENSXETG00000014768(hrb) "ENSMUSG00000026159(Agfg1),ENSMUSG00000029722(Agfg2)" "ENSG00000173744(AGFG1),ENSG00000106351(AGFG2)" "partially lethal - majority die,some die during pupal stage" FBgn0033994 CG7544 http://flybase.net/reports/FBgn0033994.html protein_coding_gene "0003676=nucleic acid binding, 0008168=methyltransferase activity" 0032259=methylation "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR002052=DNA methylase, N-6 adenine-specific, conserved site, IPR010286=Ribosomal RNA large subunit methyltransferase F-like, IPR017182=S-adenosyl-L-methionine dependent methyltransferase, Mett10D, predicted" CG7544 16-Dec-15 2015_12 ENSDARG00000055838(mett10d) WBGene00014228(mett-10) ENSXETG00000019432(METT10D) ENSMUSG00000010554(Mett10d) ENSG00000127804(METTL16) FBgn0034579 mRpL54 mitochondrial ribosomal protein L54 http://flybase.net/reports/FBgn0034579.html FBgn0046987 protein_coding_gene 0003735=structural constituent of ribosome 0032543=mitochondrial translation 0005762=mitochondrial large ribosomal subunit "BcDNA:SD09147, MRP-L54, CG9353" "IPR013870=Ribosomal protein L37, mitochondrial" CG9353 16-Dec-15 2015_12 ENSDARG00000071468(LOC100331005) WBGene00009128(F25H5.6) ENSMUSG00000034932(Mrpl54) ENSG00000183617(MRPL54) "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0031141 CG1304 http://flybase.net/reports/FBgn0031141.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP46 "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type, IPR001254=Serine proteases, trypsin domain" CG1304 16-Dec-15 2015_12 "ENSDARG00000055986(LOC100001065),ENSDARG00000055967(LOC100001138),ENSDARG00000042166(LOC100330385),ENSDARG00000056025(LOC100003650),ENSDARG00000056329,ENSDARG00000055998(LOC100003988),ENSDARG00000071389(LOC100003873),ENSDARG00000071381(LOC100004256),ENSDARG00000068466,ENSDARG00000061649,ENSDARG00000071309(LOC100006832),ENSDARG00000071296,ENSDARG00000056371(LOC100329875),ENSDARG00000071307,ENSDARG00000071301,ENSDARG00000056064(si:dkey-21e2.13),ENSDARG00000071391,ENSDARG00000027135,ENSDARG00000042134,ENSDARG00000014408(LOC100006561),ENSDARG00000056382(LOC100006228),ENSDARG00000042146(LOC100330521),ENSDARG00000071312(LOC100330235),ENSDARG00000013191,ENSDARG00000021122,ENSDARG00000056003,ENSDARG00000056068(LOC100006476),ENSDARG00000071305,ENSDARG00000071387(LOC100004043),ENSDARG00000007905,ENSDARG00000042160(LOC100006537),ENSDARG00000056199(LOC100004156),ENSDARG00000061893(LOC100329787),ENSDARG00000056072(LOC100006185),ENSDARG00000056046(LOC100006446),ENSDARG00000042144,ENSDARG00000041996(LOC100007059),ENSDARG00000071390(LOC100003706),ENSDARG00000071310(si:dkey-78l4.5),ENSDARG00000056286,ENSDARG00000056364(LOC100006267),ENSDARG00000042008(LOC558805),ENSDARG00000061620(LOC100149529)" viable FBgn0036436 CG4914 http://flybase.net/reports/FBgn0036436.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP39 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG4914 16-Dec-15 2015_12 "ENSDARG00000056324(zgc:123295),ENSDARG00000046140(zgc:112038),ENSDARG00000055644(zgc:101788),ENSDARG00000070713(zgc:162180),ENSDARG00000070710(wu:fk80d04),ENSDARG00000061858(zgc:153968),ENSDARG00000056773(zgc:163079),ENSDARG00000052064(LOC571079),ENSDARG00000063444,ENSDARG00000070518,ENSDARG00000019714" WBGene00006619(try-1) "ENSXETG00000006302(BC067937.1),ENSXETG00000006299(),ENSXETG00000025963(prss27),ENSXETG00000008526()" "ENSMUSG00000054537(Tmprss11e),ENSMUSG00000048764(Tmprss11f)" "viable,fertile" FBgn0031309 Tfb4 TFB4 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0031309.html protein_coding_gene "0008094=DNA-dependent ATPase activity, 0008353=RNA polymerase II carboxy-terminal domain kinase activity" "0006366=transcription from RNA polymerase II promoter, 0006367=transcription initiation from RNA polymerase II promoter, 0001111=promoter clearance from RNA polymerase II promoter, 0006289=nucleotide-excision repair, 0001113=transcriptional open complex formation at RNA polymerase II promoter, 0009411=response to UV, 0006355=regulation of transcription, DNA-templated" "0005634=nucleus, 0000439=core TFIIH complex, 0005675=holo TFIIH complex" "TFB4, CG5041, Tfb4, Dmp34" IPR004600=TFIIH subunit Tfb4/p34 CG5041 16-Dec-15 2015_12 "ENSDARG00000031604(gtf2h3),ENSDARG00000067560(gtf2h3-2)" YPR056W(TFB4) WBGene00014230(ZK1128.4) ENSMUSG00000029387(Gtf2h3) ENSG00000111358(GTF2H3) "viable,visible,female fertile" mesothoracic tergum DRSC26946 K 0.499302973 -0.97930976 -0.030545737 -0.178333262 1.735072587 0.093298673 FBgn0042696 NfI Nuclear factor I http://flybase.net/reports/FBgn0042696.html FBgn0039899 protein_coding_gene 0003700=sequence-specific DNA binding transcription factor activity "0006260=DNA replication, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG2380, NFI" "IPR003619=MAD homology 1, Dwarfin-type, IPR020604=CTF transcription factor/nuclear factor 1, DNA-binding domain, IPR000647=CTF transcription factor/nuclear factor 1, IPR019548=CTF transcription factor/nuclear factor 1, N-terminal" CG2380 16-Dec-15 2015_12 "ENSDARG00000043210(LOC100005568),ENSDARG00000062420(nfia),ENSDARG00000061836(zgc:136878),ENSDARG00000043226" "ENSXETG00000008149(NFIC),ENSXETG00000008871(NFIA),ENSXETG00000000835(NFIB)" "ENSMUSG00000001911(Nfix),ENSMUSG00000028565(Nfia),ENSMUSG00000008575(Nfib),ENSMUSG00000055053(Nfic)" "ENSG00000008441(NFIX),ENSG00000162599(NFIA),ENSG00000147862(NFIB),ENSG00000141905(NFIC)" viable FBgn0053886 His2B:CG33886 His2B:CG33886 http://flybase.net/reports/FBgn0053886.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33886 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000558=Histone H2B" CG33886 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0038772 mdlc midlife crisis http://flybase.net/reports/FBgn0038772.html protein_coding_gene 0008270=zinc ion binding "0022008=neurogenesis, 0043484=regulation of RNA splicing, 0030182=neuron differentiation, 0000398=mRNA splicing, via spliceosome" "0005684=U2-type spliceosomal complex, 0005634=nucleus" "mdlc, CG4973, midlife crisis" "IPR001841=Zinc finger, RING-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR000571=Zinc finger, CCCH-type" CG4973 16-Dec-15 2015_12 ENSDARG00000037930(rnf113a) YLR323C(CWC24) WBGene00010476(rnf-113) ENSXETG00000002042(ZNF183) ENSMUSG00000036537(Rnf113a1) "ENSG00000125352(RNF113A),ENSG00000139797(RNF113B)" "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,recessive,mitotic cell cycle defective,somatic clone,viable,lethal - all die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,neuroblast,somatic clone" FBgn0266666 Sem1 Sem1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266666.html "FBgn0044819, FBgn0040954, FBgn0047023" protein_coding_gene "0022008=neurogenesis, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" 0000502=proteasome complex "BcDNA:RH34416, Sem1p, Sem1, dss1, CG13779, dmdss1" IPR007834=DSS1/SEM1 CG13779 16-Dec-15 2015_12 DRSC02282 I 2.143935236 -2.093601015 -0.787468133 -0.69995419 1.191399367 0.238840768 FBgn0024288 Sox100B Sox100B http://flybase.net/reports/FBgn0024288.html "FBgn0039814, FBgn0039815, FBgn0040626" protein_coding_gene "0008301=DNA binding, bending, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0008584=male gonad development" 0005634=nucleus "SoxB, CT6009, Sox9, Sox100, CG15552, SOXE, CG18674, CG12098, SOX100B" "IPR022151=Sox developmental protein N-terminal, IPR009071=High mobility group box domain" CG15552 16-Dec-15 2015_12 "ENSDARG00000037782(sox8),ENSDARG00000043923(sox9b),ENSDARG00000003293(sox9a),ENSDARG00000068019" WBGene00004950(sox-3) ENSXETG00000014408(sox4) "ENSMUSG00000000567(Sox9),ENSMUSG00000033006(Sox10)" "ENSG00000005513(SOX8),ENSG00000125398(SOX9),ENSG00000100146(SOX10)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC15090 E -1.231355052 -0.753709228 2.263631832 -0.251926003 0.290914526 0.602503394 FBgn0085425 CG34396 http://flybase.net/reports/FBgn0085425.html "FBgn0043956, FBgn0043952, FBgn0043951, FBgn0034586, FBgn0034587" protein_coding_gene "0005267=potassium channel activity, 0005252=open rectifier potassium channel activity" 0071805=potassium ion transmembrane transport 0016021=integral component of membrane "anon-WO0109301.17, CG15655, anon-WO0109301.1, anon-WO0109301.16, CG15654" "IPR003280=Two pore domain potassium channel, IPR013099=Potassium channel domain" CG34396 16-Dec-15 2015_12 "WBGene00006685(twk-33),WBGene00006686(twk-34),WBGene00006688(twk-36),WBGene00006678(twk-25)" "lethal,viable,visible" trichogen cell DRSC04245 E -0.524740195 -1.016988458 -1.135160504 -2.498587642 0.746714656 0.340389751 FBgn0029993 CG1571 http://flybase.net/reports/FBgn0029993.html protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled" 0007018=microtubule-based movement "0005868=cytoplasmic dynein complex, 0005875=microtubule associated complex, 0030286=dynein complex" "IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR001680=WD40 repeat" CG1571 16-Dec-15 2015_12 WBGene00016165(C27F2.1) DRSC18068 I 2.272284446 0.413357801 0.186415917 0.369183187 0.053981636 0.553018447 FBgn0250844 CG4218 http://flybase.net/reports/FBgn0250844.html "FBgn0028881, FBgn0066880, FBgn0066865" protein_coding_gene "anon-SAGE:Wang-133, BG:DS04641.8, anon-SAGE:Wang-118" CG4218 16-Dec-15 2015_12 DRSC01939 K -0.563211813 -0.284712191 0.30512578 0.276890398 1.99757707 1.939138462 FBgn0003279 RpL4 Ribosomal protein L4 http://flybase.net/reports/FBgn0003279.html FBgn0046357 protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0051298=centrosome duplication" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "anon-WO0172774.76, Ribosomal protein L1, RpL1, rpL1, CG5502, Rp L4, chr3R:23749174..23749334, L4" "IPR002136=Ribosomal protein L4/L1e, IPR013000=Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site, IPR023574=Ribosomal protein L4 domain, IPR025755=60S ribosomal protein L4, C-terminal domain" CG5502 16-Dec-15 2015_12 ENSDARG00000041182(rpl4) "YDR012W(RPL4B),YBR031W(RPL4A)" WBGene00004415(rpl-4) ENSXETG00000015898(rpl4) ENSMUSG00000032399(Rpl4) ENSG00000174444(RPL4) DRSC16833 IEK 1.082745463 -1.544393439 -1.388858262 -5.047682376 1.106202201 3.04864626 FBgn0031420 Atxn7 Ataxin 7 http://flybase.net/reports/FBgn0031420.html protein_coding_gene "2001168=positive regulation of histone H2B ubiquitination, 0036285=SAGA complex assembly" "0070461=SAGA-type complex, 0005634=nucleus, 0000124=SAGA complex, 0005700=polytene chromosome" "Ataxin-7, CG9866" CG9866 16-Dec-15 2015_12 "majority die during prepupal stage,short lived,locomotor behavior defective,neuroanatomy defective,lethal,progressive" "adult brain,retina,eye,progressive" DRSC23138 K -0.613893778 0.942248093 0.233219194 1.113444305 0.729391868 1.939400138 FBgn0052016 4E-T eIF4E-Transporter http://flybase.net/reports/FBgn0052016.html "FBgn0039933, FBgn0039934" protein_coding_gene "0005737=cytoplasm, 0000932=cytoplasmic mRNA processing body, 0005634=nucleus" "CG32016, CG11097, Dm4E-T, CG11232" IPR018862=Eukaryotic translation initiation factor 4E binding protein CG32016 16-Dec-15 2015_12 ENSDARG00000016177(eif4enif1) ENSMUSG00000020454(Eif4enif1) ENSG00000184708(EIF4ENIF1) "viable,fertile" DRSC17201 E -0.811226145 -0.904777303 -1.814283801 -0.850576363 0.35606129 0.090801119 FBgn0038387 blp black pearl http://flybase.net/reports/FBgn0038387.html "FBgn0010754, FBgn0047168" protein_coding_gene "0030150=protein import into mitochondrial matrix, 0022008=neurogenesis, 0001700=embryonic development via the syncytial blastoderm, 0002168=instar larval development" 0005744=mitochondrial inner membrane presequence translocase complex "CG5268, black-pearl, l(3)01618, Blp, BcDNA:RE11908" IPR005341=Mitochondrial import inner membrane translocase subunit Tim16 CG5268 16-Dec-15 2015_12 ENSDARG00000037356(zgc:73356) YJL104W(PAM16) WBGene00009734(F45G2.8) ENSXETG00000017310(AY313218.1) "ENSMUSG00000014301(Magmas),ENSMUSG00000045886(Gm9803)" ENSG00000217930(PAM16) "lethal,recessive,partially lethal - majority die,melanotic mass phenotype,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,body color defective,some die during pupal stage" "melanotic mass,embryonic/first instar larval cuticle,segment,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC28887 K 0.572622302 0.721312543 -0.113439219 -0.028401821 0.76541783 2.51168194 FBgn0032596 Prosë_4 Proteasome ë_4 subunit http://flybase.net/reports/FBgn0032596.html protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" "0032504=multicellular organism reproduction, 0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0000502=proteasome complex, 0005839=proteasome core complex" "beta-4, CG17331, Prosbeta4, GC17331, Beta-4, PSMB2, Psmb2, beta4, 17331" "IPR001353=Proteasome, subunit alpha/beta, IPR016050=Proteasome beta-type subunit, conserved site, IPR023333=Proteasome B-type subunit, IPR029055=Nucleophile aminohydrolases, N-terminal" CG17331 16-Dec-15 2015_12 ENSDARG00000031511 YER012W(PRE1) WBGene00003950(pbs-4) ENSXETG00000009668(PSMB2) ENSMUSG00000028837(Psmb2) ENSG00000126067(PSMB2) "viable,fertile,lethal" ventral furrow DRSC02603 IE -0.712565525 -2.243417621 -1.816612613 -3.584452755 1.472082813 -0.378061121 FBgn0033321 CG8738 http://flybase.net/reports/FBgn0033321.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SPH121, c-SPH121" "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR009003=Peptidase S1, PA clan" CG8738 16-Dec-15 2015_12 "ENSG00000180210(F2),ENSG00000126218(F10),ENSG00000115718(PROC),ENSG00000122194(PLG),ENSG00000101981(F9),ENSG00000057593(F7)" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0263006 SERCA Sarco/endoplasmic reticulum Ca(2+)-ATPase http://flybase.net/reports/FBgn0263006.html "FBgn0004551, FBgn0004119, FBgn0004241, FBgn0022016, FBgn0022044, FBgn0026413, FBgn0034932, FBgn0065896" protein_coding_gene "0005515=protein binding, 0005524=ATP binding, 0046872=metal ion binding, 0005388=calcium-transporting ATPase activity" "0008610=lipid biosynthetic process, 0030322=stabilization of membrane potential, 0048863=stem cell differentiation, 1901896=positive regulation of calcium-transporting ATPase activity, 0007274=neuromuscular synaptic transmission, 0006816=calcium ion transport, 0051282=regulation of sequestering of calcium ion, 0006635=fatty acid beta-oxidation, 0060047=heart contraction, 0007629=flight behavior, 0010884=positive regulation of lipid storage, 0036335=intestinal stem cell homeostasis, 0006874=cellular calcium ion homeostasis" "0016021=integral component of membrane, 0005783=endoplasmic reticulum, 0033017=sarcoplasmic reticulum membrane, 0005789=endoplasmic reticulum membrane, 0005635=nuclear envelope, 0016529=sarcoplasmic reticulum, 0005811=lipid particle, 0012505=endomembrane system" "Ca[2+]ATPase, Ca[2+] ATPase, dserca, CA-P60A, CG3725, kum, Ca-P60, l(2)k09025, 17136664, CaP60A, ATC1_DROME, Ca-p, Kum, SERCA, A4UZU0_DROME, dSERCA, Serca2a, Kumbhakarna, sarcoplasmic endoplasmic reticulum calcium ATPase type 2, SERCA2, lethal (2) SH0211, Calcium ATPase at 60A, Ca-ATPase, sarco/endoplasmic reticulum-type Ca-2+-ATPase, calcium ATPase, organellar-type Ca-ATPase, l(2)k08308ab, l(2)SH0211, Ca-P60A, sarco endoplasmic reticulum calcium-ATPase, Serca" "IPR001757=P-type ATPase, IPR023299=P-type ATPase, cytoplasmic domain N, IPR018303=P-type ATPase, phosphorylation site, IPR008250=P-type ATPase, A domain, IPR030330=Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, IPR006068=Cation-transporting P-type ATPase, C-terminal, IPR004014=Cation-transporting P-type ATPase, N-terminal, IPR023214=HAD-like domain, IPR023298=P-type ATPase, transmembrane domain, IPR005782=P-type ATPase, subfamily IIA, SERCA-type" CG3725 16-Dec-15 2015_12 "ENSDARG00000020574(atp2a1),ENSDARG00000035458(atp2a1l),ENSDARG00000029439(atp2a2a),ENSDARG00000005122(atp2a2b),ENSDARG00000060978(atp2a3)" WBGene00004736(sca-1) "ENSXETG00000009695(atp2a1),ENSXETG00000002512(ATP2A2)" "ENSMUSG00000029467(Atp2a2),ENSMUSG00000030730(Atp2a1),ENSMUSG00000020788(Atp2a3)" "ENSG00000174437(ATP2A2),ENSG00000196296(ATP2A1),ENSG00000074370(ATP2A3)" " adult stage , adult stage | female " " ganglion cell &&of ocellus

, oocyte

, optic lobe

, skeletal muscle of mesothorax

, pharyngeal muscle

, cibarial muscle

, tubular muscle

, salivary pump muscle 13

, ocellus | vicinity of

, adult central nervous system

" FBgn0053840 His1:CG33840 His1:CG33840 http://flybase.net/reports/FBgn0053840.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33840 "IPR005818=Linker histone H1/H5, domain H15, IPR005819=Histone H5, IPR011991=Winged helix-turn-helix DNA-binding domain" CG33840 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0020622 Pi3K21B Pi3K21B http://flybase.net/reports/FBgn0020622.html "FBgn0020262, FBgn0024844" protein_coding_gene "0019900=kinase binding, 0035014=phosphatidylinositol 3-kinase regulator activity, 0043560=insulin receptor substrate binding" "0045793=positive regulation of cell size, 0045927=positive regulation of growth, 0008286=insulin receptor signaling pathway, 0046620=regulation of organ growth, 0046834=lipid phosphorylation, 0008361=regulation of cell size, 0046854=phosphatidylinositol phosphorylation, 0006468=protein phosphorylation, 0042127=regulation of cell proliferation" "0005943=phosphatidylinositol 3-kinase complex, class IA, 0005942=phosphatidylinositol 3-kinase complex" "droPIK57, CG2699, dP60, Dp60, Pi3Kp60, PI 3-kinase, dPI 3-kinase, PI(3)K, PI3K-p60, PI3K21B, dPI3K, p60, PI3K, PI3 kinase, Pi3K21B|p60, PI3-kinase, PI[[3]]K" "IPR000980=SH2 domain, IPR001720=PI3 kinase, P85 regulatory subunit" CG2699 16-Dec-15 2015_12 "ENSDARG00000034409(pik3r3),ENSDARG00000038524(LOC557176),ENSDARG00000018060(pik3r2),ENSDARG00000045829" WBGene00000001(aap-1) "ENSXETG00000003253(pik3r3),ENSXETG00000021480(PIK3R1),ENSXETG00000012933(PIK3R2)" "ENSMUSG00000041417(Pik3r1),ENSMUSG00000031834(Pik3r2),ENSMUSG00000028698(Pik3r3)" "ENSG00000117461(PIK3R3),ENSG00000145675(PIK3R1),ENSG00000105647(PIK3R2)" " embryonic stage | stage 5-10 , embryonic stage | stage 16 , embryonic stage | early , adult stage | female , embryonic stage -- adult stage , adult stage | male , adult stage " " pole cell

, prothoracic segment | restricted

, embryonic/larval midgut

, adult head

, mesothoracic segment | restricted

" larval stage&&pupal stage&&adult stage "viable,fertile,wild-type,small body,somatic clone,decreased cell size" "egg chamber,germline clone,imaginal disc & cell,embryonic/larval salivary gland,somatic clone,cell cycle | somatic clone,embryonic/larval fat body,embryonic/larval ganglionic branch,mushroom body neuroblast,embryonic/larval neuroblast" FBgn0030332 CG9360 http://flybase.net/reports/FBgn0030332.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process FOHSDR "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG9360 16-Dec-15 2015_12 "ENSDARG00000031299(dhrs11b),ENSDARG00000046090(dhrs11a),ENSDARG00000004141(zgc:92630)" ENSXETG00000002036(TEgg038a23.1) ENSMUSG00000034449(Dhrs11) ENSG00000108272(DHRS11) viable FBgn0040060 yip7 yippee interacting protein 7 http://flybase.net/reports/FBgn0040060.html FBgn0035662 protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "SP116, CG6457, mac, machete, Machete, MAC, SPH116" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG6457 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0034035 CG8207 http://flybase.net/reports/FBgn0034035.html protein_coding_gene 0004475=mannose-1-phosphate guanylyltransferase activity 0009058=biosynthetic process unnamed "IPR029044=Nucleotide-diphospho-sugar transferases, IPR001451=Hexapeptide repeat, IPR005835=Nucleotidyl transferase domain" CG8207 16-Dec-15 2015_12 "ENSDARG00000024112,ENSDARG00000023498(gmppab)" WBGene00021628(Y47D9A.1) ENSXETG00000019242(GMPPA) ENSMUSG00000033021(Gmppa) ENSG00000144591(GMPPA) viable FBgn0030575 CG5321 http://flybase.net/reports/FBgn0030575.html FBgn0027675 protein_coding_gene 0008336=gamma-butyrobetaine dioxygenase activity 0055114=oxidation-reduction process anon-EST:Posey66 "IPR003819=TauD/TfdA-like domain, IPR010376=Domain of unknown function DUF971" CG5321 16-Dec-15 2015_12 ENSDARG00000036135(bbox1) YHL021C(AIM17) WBGene00001522(gbh-1) ENSXETG00000004606(BBOX1) ENSMUSG00000041660(Bbox1) ENSG00000129151(BBOX1) viable FBgn0020506 Amyrel Amyrel http://flybase.net/reports/FBgn0020506.html protein_coding_gene "0004556=alpha-amylase activity, 0003824=catalytic activity, 0043169=cation binding, 0004574=oligo-1,6-glucosidase activity" 0005975=carbohydrate metabolic process "CG8221, AmyRel, amyrel" "IPR017853=Glycoside hydrolase superfamily, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR015902=Glycoside hydrolase, family 13, IPR013780=Glycosyl hydrolase, family 13, all-beta, IPR013781=Glycoside hydrolase, catalytic domain, IPR006048=Alpha-amylase/branching enzyme, C-terminal all beta, IPR031319=Alpha-amylase, C-terminal domain, IPR006046=Alpha amylase" CG8221 16-Dec-15 2015_12 "ENSDARG00000013856(amy2a),ENSDARG00000030357(zgc:66313),ENSDARG00000009443(zgc:92137)" WBGene00008220(C50B6.7) "ENSXETG00000010847(),ENSXETG00000010846(amy1a)" "ENSMUSG00000074266(Amy2a3),ENSMUSG00000074268(Amy2a5),ENSMUSG00000079850,ENSMUSG00000074267(Amy2a4),ENSMUSG00000074264(Amy1)" "ENSG00000197839,ENSG00000196318,ENSG00000174876(AMY1B),ENSG00000051415,ENSG00000187733(AMY1C)" " larval stage | third instar , larval stage | second instar " FBgn0053888 His2B:CG33888 His2B:CG33888 http://flybase.net/reports/FBgn0053888.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33888 "IPR009072=Histone-fold, IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3" CG33888 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0037481 MAGE MAGE http://flybase.net/reports/FBgn0037481.html protein_coding_gene 0019789=SUMO transferase activity "0006281=DNA repair, 0031000=response to caffeine, 0006974=cellular response to DNA damage stimulus, 0043524=negative regulation of neuron apoptotic process, 0007406=negative regulation of neuroblast proliferation, 0048812=neuron projection morphogenesis" "0005634=nucleus, 0030915=Smc5-Smc6 complex" "sst, sleepless in seattle, DMAGE, Nse3, Necdin, CG10059, Mage" IPR002190=MAGE homology domain CG10059 16-Dec-15 2015_12 ENSDARG00000058212(ndnl2) ENSXETG00000022031() "ENSMUSG00000070520(Ndnl2),ENSMUSG00000031227(Magee1),ENSMUSG00000067649(Mageb18),ENSMUSG00000043453(Magea10),ENSMUSG00000031118(1700080O16Rik),ENSMUSG00000074881(Mageb3),ENSMUSG00000073069(Mageb2),ENSMUSG00000062162(Mageb1),ENSMUSG00000046180(4930550L24Rik),ENSMUSG00000079349(Magea5),ENSMUSG00000046942(Mageb16),ENSMUSG00000033585(Ndn),ENSMUSG00000056972(Magel2),ENSMUSG00000079350(Magea8),ENSMUSG00000055816(Magea3),ENSMUSG00000073068(Gm8914),ENSMUSG00000067650(Gm5072),ENSMUSG00000063728(Magea6),ENSMUSG00000059539(Magea1),ENSMUSG00000078123(Gm5071),ENSMUSG00000031179(3830417A13Rik),ENSMUSG00000055746(Magea2),ENSMUSG00000061392(Mageb5),ENSMUSG00000045330(4933402E13Rik),ENSMUSG00000064129(Gm14781),ENSMUSG00000033343(Magea4)" "ENSG00000189023(MAGEB16),ENSG00000124260(MAGEA10),ENSG00000176774(MAGEB18),ENSG00000185247(MAGEA11),ENSG00000214107(MAGEB1),ENSG00000177689(MAGEB10),ENSG00000156009(MAGEA8),ENSG00000120289(MAGEB4),ENSG00000147381(MAGEA4),ENSG00000198798(MAGEB3),ENSG00000166008(MAGEA9),ENSG00000123584(MAGEA9B),ENSG00000182798(MAGEB17),ENSG00000099399(MAGEB2),ENSG00000198681(MAGEA1),ENSG00000184750(MAGEA2),ENSG00000183305,ENSG00000197172(MAGEA6),ENSG00000221867(MAGEA3),ENSG00000213401(MAGEA12),ENSG00000046774(MAGEC2),ENSG00000188408,ENSG00000185115(NDNL2),ENSG00000176746(MAGEB6),ENSG00000177383(MAGEF1),ENSG00000182636(NDN),ENSG00000187601(MAGEH1)" "visible,somatic clone,conditional,chemical sensitive,increased cell death,lethal,radiation sensitive,partially lethal,viable,recessive,increased cell number,neuroanatomy defective" "eye,somatic clone,conditional,eye disc,photoreceptor cell,adult brain,neuron,supernumerary,adult mushroom body" FBgn0032651 Oli Olig family http://flybase.net/reports/FBgn0032651.html protein_coding_gene "0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0008045=motor neuron axon guidance, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "CG5545, Olig, bHLHb23, Doli, oli" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG5545 16-Dec-15 2015_12 "ENSDARG00000058039(bhlhe22),ENSDARG00000037588(bhlhe23)" ENSXETG00000006104(BHLHE23) ENSMUSG00000025128(Bhlhe22) "ENSG00000125533(BHLHE23),ENSG00000180828(BHLHE22)" "neuroanatomy defective,lethal,some die during embryonic stage,locomotor behavior defective,flightless,viable" "intersegmental nerve branch ISNb of A1-7 | embryonic stage,intersegmental nerve branch ISNb of A1-7,transverse nerve,abdominal intersegmental bidendritic neuron isbp" FBgn0052473 CG32473 http://flybase.net/reports/FBgn0052473.html "FBgn0038137, FBgn0038138" protein_coding_gene "0004177=aminopeptidase activity, 0008237=metallopeptidase activity, 0008270=zinc ion binding" 0006508=proteolysis "CG8775, CG11688, GM08240p" "IPR001930=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782=Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571=ERAP1-like C-terminal domain" CG32473 16-Dec-15 2015_12 ENSDARG00000057064 WBGene00009865(F49B2.6) ENSXETG00000013333(ENPEP) ENSMUSG00000028024(Enpep) ENSG00000138792(ENPEP) viable FBgn0266465 GckIII Germinal centre kinase III http://flybase.net/reports/FBgn0266465.html "FBgn0264670, FBgn0086736, FBgn0086325, FBgn0038477" protein_coding_gene "0004702=receptor signaling protein serine/threonine kinase activity, 0004672=protein kinase activity, 0005524=ATP binding, 0042803=protein homodimerization activity" "0007430=terminal branching, open tracheal system, 0019991=septate junction assembly, 0006468=protein phosphorylation, 0007015=actin filament organization, 0060439=trachea morphogenesis" 0005794=Golgi apparatus "STLK3, germinal center kinase III, Germinal Center Kinase III, GCKIII, wheezy, dGCKIII, CG5169" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain" CG5169 16-Dec-15 2015_12 "ENSDARG00000039022(stk25),ENSDARG00000002210(zgc:92836),ENSDARG00000023878(stk24b),ENSDARG00000060390(LOC559023),ENSDARG00000031413(stk24a)" YDR523C(SPS1) WBGene00001526(gck-1) "ENSXETG00000002989(stk25),ENSXETG00000023524(STK24)" "ENSMUSG00000063410(Stk24),ENSMUSG00000026277(Stk25),ENSMUSG00000031112(2610018G03Rik)" "ENSG00000102572(STK24),ENSG00000134602(MST4),ENSG00000115694(STK25)" DRSC15729 IE 0.947726084 -2.019776689 -0.819480418 -2.201211832 0.735340256 0.586874372 FBgn0030607 dob doppelganger von brummer http://flybase.net/reports/FBgn0030607.html protein_coding_gene 0004806=triglyceride lipase activity 0019433=triglyceride catabolic process "Dob, CG5560" "IPR016035=Acyl transferase/acyl hydrolase/lysophospholipase, IPR002641=Patatin/Phospholipase A2-related" CG5560 16-Dec-15 2015_12 WBGene00015484(C05D11.7) "ENSXETG00000004865(Q5FWR9_XENTR),ENSXETG00000019027(PNPLA2)" "ENSMUSG00000025509(Pnpla2),ENSMUSG00000041653(Pnpla3)" "ENSG00000177666(PNPLA2),ENSG00000100344(PNPLA3),ENSG00000100341(PNPLA5)" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0051915 CG31915 http://flybase.net/reports/FBgn0051915.html FBgn0031712 protein_coding_gene 0008475=procollagen-lysine 5-dioxygenase activity CG6922 "IPR029044=Nucleotide-diphospho-sugar transferases, IPR002654=Glycosyl transferase, family 25" CG31915 16-Dec-15 2015_12 "ENSDARG00000058270(glt25d1),ENSDARG00000014670(glt25d2)" WBGene00008426(D2045.9) "ENSXETG00000017443(GLT25D2),ENSXETG00000009835(CERCAM),ENSXETG00000020570(GLT25D1)" "ENSMUSG00000032649(Glt25d2),ENSMUSG00000034807(Glt25d1),ENSMUSG00000039787(Cercam)" "ENSG00000198756(GLT25D2),ENSG00000130309(GLT25D1),ENSG00000167123(CERCAM)" viable DRSC03000 K -0.941905526 0.549413336 -0.174662515 0.349777009 0.236452697 2.163769432 FBgn0035965 Use1 USE1 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0035965.html protein_coding_gene 0005484=SNAP receptor activity "0006890=retrograde vesicle-mediated transport, Golgi to ER, 0022008=neurogenesis, 0009306=protein secretion, 0007030=Golgi organization" "0071458=integral component of cytoplasmic side of endoplasmic reticulum membrane, 0031201=SNARE complex, 0005783=endoplasmic reticulum, 0012505=endomembrane system" "FBgn 35965, CG14181, Unconventional SNARE in the ER 1 ortholog (S. cerevisiae), Use1" "IPR019150=Vesicle transport protein, Use1" CG14181 16-Dec-15 2015_12 ENSDARG00000007250(zgc:56402) WBGene00022460(use-1) ENSXETG00000013513(USE1) ENSMUSG00000002395(Use1) ENSG00000053501(USE1) "lethal,neuroanatomy defective" ganglion mother cell DRSC10180 K 0.263451844 0.705092279 1.129383434 0.066709439 -1.09752482 -2.13369899 FBgn0036147 Plod procollagen lysyl hydroxylase http://flybase.net/reports/FBgn0036147.html "FBgn0026285, FBgn0062024" protein_coding_gene "0031418=L-ascorbic acid binding, 0005506=iron ion binding, 0008475=procollagen-lysine 5-dioxygenase activity" "0055114=oxidation-reduction process, 0007295=growth of a germarium-derived egg chamber" "0048471=perinuclear region of cytoplasm, 0005615=extracellular space, 0005783=endoplasmic reticulum" "anon-EST:ParkEST325, LH3, Drosophila Plod, RE-H, anon-WO0118547.416, CG6199, lysyl hydroxylase, dPlod" "IPR029044=Nucleotide-diphospho-sugar transferases, IPR005123=Oxoglutarate/iron-dependent dioxygenase, IPR006620=Prolyl 4-hydroxylase, alpha subunit" CG6199 16-Dec-15 2015_12 "ENSDARG00000060715(plod1b),ENSDARG00000011821(plod2),ENSDARG00000059746(plod1a)" WBGene00002497(let-268) "ENSXETG00000013055(PLOD1),ENSXETG00000001628(PLOD2)" "ENSMUSG00000004846(Plod3),ENSMUSG00000032374(Plod2),ENSMUSG00000019055(Plod1)" "ENSG00000106397(PLOD3),ENSG00000152952(PLOD2),ENSG00000083444(PLOD1)" "viable,fertile" egg FBgn0003884 ë±Tub84B ë±-Tubulin at 84B http://flybase.net/reports/FBgn0003884.html FBgn0046254 protein_coding_gene "0005525=GTP binding, 0005200=structural constituent of cytoskeleton, 0003924=GTPase activity" "0007094=mitotic spindle assembly checkpoint, 0051258=protein polymerization, 0019730=antimicrobial humoral response, 0007052=mitotic spindle organization" "0005813=centrosome, 0000235=astral microtubule, 0005874=microtubule, 0005737=cytoplasm, 0005634=nucleus, 0005819=spindle, 0048471=perinuclear region of cytoplasm, 0045298=tubulin complex" "l(3)g3, anon-EST:Liang-1.59, alpha1 tubulin, DTA1, TBA1_DROME, alpha-Tub84B, alphatubulin, tubA84B, Tuba84B, alphaTub84B, tubulin(alpha1), CG1913, tub, alpha-tubulin 84B, Tubulin, tubulin, alphaTUB, tubalpha1, Talpha1, a1t, alphaTubulin84B, Alpha tubulin, alpha tubulin, ALPHA 84C, alpha-Tubulin, alpha-tubulin84B, alpha tubulin 84B, alphatub, alpha-Tubulin at 84B, Tubalpha1, tubulin alpha1, alphat-1, alpha-Tub, alpha-tub84B, alpha1tub84B, alpha1tub, aTub84B, l(3)84Bd, alphatub84B, Tubulin 1 alpha-chain, alpha[[1]]-tubulin, tubulin84B, alphaTub84, alpha[[1]] tubulin, alpha-tubulin, alphaT, alphaTub, alphaTub1, ms(3)nc33, alpha-tubulin 1, alphaTubulin 84B, tubulin1alpha, alpha-tub, alphaTUB84B, BEST:LD32507, anon-EST:Liang-2.30, Tubulin-alpha1, alpha1t, alpha1-tubulin, DM1alpha, chr3R:2914276..2914416, alpha84B, tubulin alpha1 promoter, alpha-Tubulin 84B, alpha1, 1t, nc33, clone 1.59, a-tub84B, T, clone 2.30, tubulin 1alpha, Tub, alpha-Tubulin84B" "IPR003008=Tubulin/FtsZ, GTPase domain, IPR023123=Tubulin, C-terminal, IPR002452=Alpha tubulin, IPR008280=Tubulin/FtsZ, C-terminal, IPR017975=Tubulin, conserved site, IPR000217=Tubulin, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain" CG1913 16-Dec-15 2015_12 "ENSDARG00000001889(tuba1l2),ENSDARG00000055216(tuba1l),ENSDARG00000036700(LOC795591),ENSDARG00000045014(tuba2)" "YML085C(TUB1),YML124C(TUB3)" WBGene00003175(mec-12) "ENSXETG00000011186(TUBA1A),ENSXETG00000011185(TUBA1B),ENSXETG00000019254(tuba3),ENSXETG00000019246(tuba3)" "ENSMUSG00000072235(Tuba1a),ENSMUSG00000067702(Tuba3a),ENSMUSG00000067338(Tuba3b),ENSMUSG00000023004(Tuba1b),ENSMUSG00000043091(Tuba1c)" "ENSG00000198033(TUBA3C),ENSG00000075886(TUBA3D),ENSG00000167552(TUBA1A),ENSG00000123416(TUBA1B),ENSG00000167553(TUBA1C),ENSG00000152086(TUBA3E)" " adult stage , embryonic stage -- adult stage , larval stage , embryonic stage | 0-12 hr , pupal stage , larval stage | third instar , larval stage | second instar , larval stage | first instar , embryonic stage | 0-21 hr , prepupal stage " " embryonic stage | 16-20 hr , adult stage , larval stage | third instar , embryonic stage | 9-13 hr , pupal stage | mid , embryonic stage | 0-2 hr " " gonad

, adult head

, central nervous system

, imaginal disc

" "lethal,recessive,male semi-sterile,wild-type,male fertile,viable,male sterile,female fertile,poor,partially lethal - majority die,visible" "spermatid,synapse & microtubulehow-24B,mesothoracic tergum" DRSC12622 IE 2.782451514 -1.294286144 4.548484602 -3.53251495 -0.082349808 0.165059518 FBgn0250814 UQCR-C2 Ubiquinol-cytochrome c reductase core protein 2 http://flybase.net/reports/FBgn0250814.html "FBgn0036642, FBgn0025538, FBgn0046299" protein_coding_gene "0046872=metal ion binding, 0008121=ubiquinol-cytochrome-c reductase activity" "0006122=mitochondrial electron transport, ubiquinol to cytochrome c" "0005811=lipid particle, 0005739=mitochondrion, 0005875=microtubule associated complex, 0005750=mitochondrial respiratory chain complex III" "anon-EST:Posey245, Ubiquinol-cytochrome c oxidoreductase Core protein 2, Ubiquinol-cytochrome c reductase Core protein 2, Ubiquinol-cytochrome C reductase complex core protein 2, ubiquinol-cytochrome c reductase, CG 4169, CG4169, BEST:GH10978, UCR2" "IPR011249=Metalloenzyme, LuxS/M16 peptidase-like, IPR011765=Peptidase M16, N-terminal, IPR011237=Peptidase M16 domain, IPR007863=Peptidase M16, C-terminal" CG4169 16-Dec-15 2015_12 "ENSDARG00000071691(uqcrc2),ENSDARG00000014794(zgc:92453)" "WBGene00011679(ucr-2.2),WBGene00020757(ucr-2.3),WBGene00012158(ucr-2.1)" ENSXETG00000016693(uqcrc2) ENSMUSG00000030884(Uqcrc2) ENSG00000140740(UQCRC2) FBgn0037170 Trxr-2 thioredoxin reductase 2 http://flybase.net/reports/FBgn0037170.html protein_coding_gene "0004791=thioredoxin-disulfide reductase activity, 0050660=flavin adenine dinucleotide binding, 0016209=antioxidant activity" "0055114=oxidation-reduction process, 0045454=cell redox homeostasis" 0005739=mitochondrion "Dm-TrxR, thioredoxin-reductase-2, TrxR, DmTrx, Trxr2, DmTrxR-2, TRR, trxr-2, thioredoxin reductase, CG11401" "IPR016156=FAD/NAD-linked reductase, dimerisation domain, IPR004099=Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR023753=Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, IPR006338=Thioredoxin/glutathione reductase selenoprotein, IPR012999=Pyridine nucleotide-disulphide oxidoreductase, class I, active site" CG11401 16-Dec-15 2015_12 ENSDARG00000017864 YPL091W(GLR1) WBGene00015553(trxr-1) ENSXETG00000006307(TXNRD2) ENSMUSG00000075704(Txnrd2) ENSG00000184470(TXNRD2) viable FBgn0033055 Tbce Tubulin-specific chaperone E http://flybase.net/reports/FBgn0033055.html protein_coding_gene "0022008=neurogenesis, 0007021=tubulin complex assembly, 0008582=regulation of synaptic growth at neuromuscular junction, 0007274=neuromuscular synaptic transmission, 0046785=microtubule polymerization" 0005737=cytoplasm "Tubulin-specific chaperone E, tbce, CG7861, TBCE, tubulin-specific chaperone E" "IPR029071=Ubiquitin-related domain, IPR000938=CAP Gly-rich domain" CG7861 16-Dec-15 2015_12 ENSDARG00000044634(tbce) YER007W(PAC2) WBGene00019503(K07H8.1) ENSXETG00000013067(tbce) ENSMUSG00000039233(Tbce) ENSG00000116957(TBCE) "locomotor behavior defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,lethal - all die before end of pupal stage,some die during pupal stage,viable" "embryonic/larval neuromuscular junction,NMJ bouton,microtubuleC57,microtubule & neuromuscular junction,longitudinal connective,ventral nerve cord,embryonic/larval neuroblast,ganglion mother cell,microtubuleED1484)" FBgn0035140 CG17180 http://flybase.net/reports/FBgn0035140.html protein_coding_gene IPR019314=Protein of unknown function DUF2365 CG17180 16-Dec-15 2015_12 ENSDARG00000061023(si:dkey-72l14.4) ENSMUSG00000045176(2310047M10Rik) ENSG00000196544(C17orf59) viable FBgn0029503 CHORD CHORD http://flybase.net/reports/FBgn0029503.html FBgn0039162 protein_coding_gene 0008270=zinc ion binding "0050773=regulation of dendrite development, 0051298=centrosome duplication, 0008361=regulation of cell size" "Q9U4A3, CHORD containing protein, morgana/chp-1, CG6198, mora, morgana, chp" "IPR007052=CS domain, IPR007051=CHORD domain, IPR008978=HSP20-like chaperone" CG6198 16-Dec-15 2015_12 "ENSDARG00000017067(chordc1),ENSDARG00000030176(zgc:92429)" WBGene00000502(chp-1) ENSXETG00000020870(ITGB1BP2) ENSMUSG00000001774(Chordc1) ENSG00000110172(CHORDC1) "mitotic cell cycle defective,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,embryonic/larval salivary gland,testis,condensed chromosome | third instar larval stage,neuroblast,centrosome | third instar larval stage" FBgn0036569 CG5414 http://flybase.net/reports/FBgn0036569.html protein_coding_gene "0002161=aminoacyl-tRNA editing activity, 0004822=isoleucine-tRNA ligase activity, 0005524=ATP binding" 0006428=isoleucyl-tRNA aminoacylation 0005737=cytoplasm "IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR002300=Aminoacyl-tRNA synthetase, class Ia, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR002301=Isoleucine-tRNA ligase, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR009008=Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR023585=Isoleucine-tRNA ligase, type 1, IPR013155=Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding" CG5414 16-Dec-15 2015_12 ENSDARG00000044134(iars2) YPL040C(ISM1) WBGene00002153(iars-2) ENSXETG00000002726(IARS2) ENSMUSG00000026618(Iars2) ENSG00000067704(IARS2) "viable,visible" trichogen cell FBgn0264753 Rgk1 "Rad, Gem/Kir family member 1" http://flybase.net/reports/FBgn0264753.html "FBgn0034434, FBgn0050127" protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0015031=protein transport, 1901386=negative regulation of voltage-gated calcium channel activity, 0007264=small GTPase mediated signal transduction" 0016020=membrane "Rgk1, CT27512, CG30127, CG9811, RGK1, CG44011" "IPR001806=Small GTPase superfamily, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020849=Small GTPase superfamily, Ras type, IPR003579=Small GTPase superfamily, Rab type, IPR021349=Protein of unknown function DUF2967" CG44011 16-Dec-15 2015_12 "ENSDARG00000052011(rrad),ENSDARG00000020544(rem1),ENSDARG00000029112(gem)" WBGene00013124(Y52B11A.4) "ENSXETG00000013757(REM2),ENSXETG00000017408(rrad),ENSXETG00000014678(GEM),ENSXETG00000024013(REM1)" "ENSMUSG00000031880(Rrad),ENSMUSG00000028214(Gem),ENSMUSG00000000359(Rem1),ENSMUSG00000022176(Rem2)" "ENSG00000166592(RRAD),ENSG00000164949(GEM),ENSG00000139890(REM2)" DRSC05786 I 0.814083046 1.680364897 -0.619960693 -0.133239548 -0.269649279 -0.034355888 FBgn0033679 CG8888 http://flybase.net/reports/FBgn0033679.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors" 0008152=metabolic process 0005886=plasma membrane "IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain" CG8888 16-Dec-15 2015_12 "ENSDARG00000059388(zgc:163053),ENSDARG00000038969(zgc:113142)" "WBGene00000983(dhs-20),WBGene00000979(dhs-16),WBGene00000966(dhs-2),WBGene00018885(F55E10.6)" "ENSXETG00000003457(),ENSXETG00000003458(BDH1),ENSXETG00000025417()" "ENSMUSG00000046598(Bdh1),ENSMUSG00000040134(Rdh7),ENSMUSG00000040127(Sdr9c7),ENSMUSG00000054052(Rdh19),ENSMUSG00000069456(Rdh16),ENSMUSG00000074640(Rdh1),ENSMUSG00000074639(BC089597),ENSMUSG00000056148(Rdh9)" ENSG00000161267(BDH1) "viable,fertile" FBgn0035497 CG14995 http://flybase.net/reports/FBgn0035497.html "FBgn0044443, FBgn0044616, FBgn0045265, FBgn0045286" protein_coding_gene "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death" "bs17f06.y1, NEST:bs17f06, CT34848, Gandalf, anon-WO0140519.252, NEST:bs15f01" "IPR025875=Leucine rich repeat 4, IPR001611=Leucine-rich repeat, IPR003603=U2A'/phosphoprotein 32 family A, C-terminal" CG14995 16-Dec-15 2015_12 ENSXETG00000015297(Q6P4K9_XENTR) ENSMUSG00000020284(1810043G02Rik) ENSG00000160226(C21orf2) "viable,fertile" DRSC22991 K -2.271326693 1.445482122 FBgn0037094 CG7611 http://flybase.net/reports/FBgn0037094.html protein_coding_gene 0005737=cytoplasm WDR26 "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat, IPR006594=LIS1 homology motif, IPR020472=G-protein beta WD-40 repeat, IPR019775=WD40 repeat, conserved site, IPR006595=CTLH, C-terminal LisH motif" CG7611 16-Dec-15 2015_12 "ENSDARG00000006812(si:ch211-153j24.6),ENSDARG00000062310(LOC559461)" YCL039W(GID7) WBGene00021482(Y39H10A.6) ENSXETG00000018563(wdr26) ENSMUSG00000038733(Wdr26) ENSG00000162923(WDR26) "viable,fertile,visible" "trichogen cell,mesothoracic tergum" DRSC11840 E -0.84929182 -0.109719642 -1.753933469 -1.839069851 -0.143188424 0.844279045 FBgn0034816 CG3085 http://flybase.net/reports/FBgn0034816.html FBgn0044759 protein_coding_gene anon-WO0140519.123 IPR000435=Tektin CG3085 16-Dec-15 2015_12 ENSDARG00000028973(tekt2) ENSXETG00000004373(tekt2) ENSMUSG00000028845(Tekt2) ENSG00000092850(TEKT2) viable FBgn0037913 fabp fatty acid bindin protein http://flybase.net/reports/FBgn0037913.html "FBgn0025540, FBgn0044763, FBgn0051305, FBgn0064779, FBgn0064804, FBgn0064806, FBgn0064848, FBtr0089774, FBpp0088715, FBtr0089775, FBpp0088716, FBtr0089776, FBpp0088717, FBtr0089777, FBpp0088718, FBtr0089778, FBpp0088719, FBtr0089779, FBpp0088720, FBtr0089780, FBpp0088721" protein_coding_gene "0005215=transporter activity, 0005504=fatty acid binding" "0006810=transport, 0007616=long-term memory" "0005829=cytosol, 0005654=nucleoplasm, 0005875=microtubule associated complex" "CG6783, BcDNA:RH06221, CT21061, BcDNA:SD12036, CG31305, anon-WO0140519.12, CG31305-PI, dFabp, anon-EST:Posey234, fatty-acid binding protein, BcDNA:RH49003, BcDNA:RH46282" "IPR000463=Cytosolic fatty-acid binding, IPR012674=Calycin, IPR000566=Lipocalin/cytosolic fatty-acid binding domain, IPR031259=Intracellular lipid binding protein, IPR011038=Calycin-like" CG6783 16-Dec-15 2015_12 "ENSDARG00000023290(fabp3),ENSDARG00000034650(fabp7b),ENSDARG00000007697(fabp7a),ENSDARG00000017299(fabp11a),ENSDARG00000002311(fabp11b)" "WBGene00002258(lbp-6),WBGene00002257(lbp-5),WBGene00002259(lbp-7),WBGene00002260(lbp-8)" "ENSXETG00000023297(fabp7),ENSXETG00000012916(fabp7b),ENSXETG00000010420(),ENSXETG00000010419()" "ENSMUSG00000028773(Fabp3),ENSMUSG00000019874(Fabp7),ENSMUSG00000062515(Fabp4),ENSMUSG00000052468(Pmp2),ENSMUSG00000027528(Fabp9),ENSMUSG00000027530(Fabp12),ENSMUSG00000027533(Fabp5)" "ENSG00000121769(FABP3),ENSG00000170323(FABP4),ENSG00000147588(PMP2),ENSG00000164434(FABP7),ENSG00000205186(FABP9),ENSG00000197416(FABP12),ENSG00000164687(FABP5)" "long lived,RU486 conditional,memory defective,heat sensitive,sleep defective,viable,oxidative stress response defective" "germline cell,male" FBgn0031044 MKP-4 MAPK Phosphatase 4 http://flybase.net/reports/FBgn0031044.html protein_coding_gene "0016791=phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0008138=protein tyrosine/serine/threonine phosphatase activity" "0006470=protein dephosphorylation, 0043508=negative regulation of JUN kinase activity" 0005634=nucleus "DMKP-4, MKP-like, Mkp4, CG14211" "IPR024950=Dual specificity phosphatase, IPR000340=Dual specificity phosphatase, catalytic domain, IPR000387=Tyrosine specific protein phosphatases domain, IPR016278=Dual specificity protein phosphatase 12, IPR029021=Protein-tyrosine phosphatase-like, IPR016130=Protein-tyrosine phosphatase, active site, IPR020422=Dual specificity protein phosphatase domain" CG14211 16-Dec-15 2015_12 ENSDARG00000029649 YIR026C(YVH1) WBGene00007697(C24F3.2) ENSXETG00000000786(dusp12) ENSMUSG00000026659(Dusp12) ENSG00000081721(DUSP12) viable DRSC19567 E 0.488115098 0.356200806 2.091639881 1.243284881 1.023980776 0.216916257 FBgn0053849 His1:CG33849 His1:CG33849 http://flybase.net/reports/FBgn0053849.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33849 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5, IPR005818=Linker histone H1/H5, domain H15" CG33849 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0035678 CG10469 http://flybase.net/reports/FBgn0035678.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP123 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG10469 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" viable FBgn0015737 Hmu Hemomucin http://flybase.net/reports/FBgn0015737.html FBgn0010259 protein_coding_gene "0004872=receptor activity, 0016844=strictosidine synthase activity, 0003729=mRNA binding, 0004252=serine-type endopeptidase activity" "0006508=proteolysis, 0009058=biosynthetic process" "0005811=lipid particle, 0012505=endomembrane system, 0009986=cell surface" "hemomucin, Rbp5, rrm5, SPH210, CG3373, RRM5, RNA-binding protein 5" "IPR011042=Six-bladed beta-propeller, TolB-like, IPR018119=Strictosidine synthase, conserved region" CG3373 16-Dec-15 2015_12 ENSDARG00000017422(bscv) "WBGene00010197(F57C2.5),WBGene00007438(C08E8.2)" "ENSXETG00000007319(Q5FVB7_XENTR),ENSXETG00000012773(C20orf3)" ENSMUSG00000033096(2310001A20Rik) ENSG00000101474(C20orf3) " embryonic stage&&larval stage&&adult stage , adult stage , adult stage && oogenesis stage " " adult proventriculus

, adult midgut

, ovary

, follicle cell

" " adult stage , adult stage && oogenesis stage " " adult proventriculus

, Malpighian tubule

, hemocyte

, adult midgut

, follicle cell

, ovary

" "viable,visible" mesothoracic tergum FBgn0000032 Acph-1 Acid phosphatase 1 http://flybase.net/reports/FBgn0000032.html FBgn0039729 protein_coding_gene "0003993=acid phosphatase activity, 0042803=protein homodimerization activity" 0016311=dephosphorylation "0070062=extracellular exosome, 0005634=nucleus" "Acph, CG7899, acid phosphatase, ACP, APH, ACPH" "IPR000560=Histidine phosphatase superfamily, clade-2, IPR029033=Histidine phosphatase superfamily" CG7899 16-Dec-15 2015_12 ENSDARG00000007244 WBGene00015161(pho-5) "ENSXETG00000003979(ACP2),ENSXETG00000000300(ACPT)" "ENSMUSG00000032561(Acpp),ENSMUSG00000002103(Acp2),ENSMUSG00000012777(Acpt)" "ENSG00000014257(ACPP),ENSG00000134575(ACP2),ENSG00000142513(ACPT)" embryonic stage -- adult stage "electrophoretic variant,fast,slow,viable,fertile" FBgn0036309 Hip1 Huntingtin interacting protein 1 http://flybase.net/reports/FBgn0036309.html protein_coding_gene "0005543=phospholipid binding, 0030276=clathrin binding, 0003779=actin binding" "0007010=cytoskeleton organization, 0006897=endocytosis" "CG10971, Hip1R" "IPR002558=I/LWEQ domain, IPR008942=ENTH/VHS, IPR013809=ENTH domain, IPR011417=AP180 N-terminal homology (ANTH) domain, IPR030224=Sla2 family" CG10971 16-Dec-15 2015_12 "ENSDARG00000062972(hip1),ENSDARG00000059484(zgc:158784),ENSDARG00000060627" YNL243W(SLA2) "ENSXETG00000005793(HIP1R),ENSXETG00000005880(HIP1)" "ENSMUSG00000000915(Hip1r),ENSMUSG00000039959(Hip1)" "ENSG00000130787(HIP1R),ENSG00000127946(HIP1)" "visible,viable" "microchaeta & mesothoracic tergumap-md544,microchaeta & mesothoracic tergumpnr-MD237" FBgn0001208 Hn Henna http://flybase.net/reports/FBgn0001208.html "FBgn0003737, FBgn0004089, FBgn0005770, FBgn0024922" protein_coding_gene "0004510=tryptophan 5-monooxygenase activity, 0004505=phenylalanine 4-monooxygenase activity, 0005506=iron ion binding, 0016597=amino acid binding" "0055114=oxidation-reduction process, 0007616=long-term memory, 0006909=phagocytosis, 0006559=L-phenylalanine catabolic process, 0006726=eye pigment biosynthetic process" 0005811=lipid particle "DTPH, TRH, Tph, bu, PAH, pah, Trh, phenylalanine hydroxylase, Phenylalanine-hydroxylase, Pah, brunette, Tryptophan hydrolase, phenylalanine-tryptophan hydroxylase, TPH, CG7399, henna" "IPR019774=Aromatic amino acid hydroxylase, C-terminal, IPR019773=Tyrosine 3-monooxygenase-like, IPR002912=ACT domain, IPR005961=Phenylalanine-4-hydroxylase, tetrameric form, IPR001273=Aromatic amino acid hydroxylase, IPR018301=Aromatic amino acid hydroxylase, iron/copper binding site" CG7399 16-Dec-15 2015_12 ENSDARG00000020143(pah) WBGene00000240(pah-1) ENSXETG00000019626(PAH) ENSMUSG00000020051(Pah) ENSG00000171759(PAH) " embryonic stage | 0-6 hr , larval stage | third instar , adult stage , larval stage , embryonic stage--larval stage , embryonic stage | stage 1-11 " " mouthpart

, embryonic/larval fat body

, adult head

, organism

, third instar larval cuticle

" " adult stage , larval stage | third instar , larval stage , pupal stage , embryonic stage | stage 1-11 , larval stage--pupal stage " " adult head

, embryonic/larval fat body

, central nervous system | restricted

, ventral nerve cord | restricted & segmentally repeated

, head

, larval brain | restricted

, neuron &&of ventral nerve cord | medial & segmentally repeated

, organism

, neuron &&of abdominal neuromere | dorso-lateral & segmentally repeated

, neuron &&of ventral nerve cord | ventro-lateral & segmentally repeated

" "eye color defective,recessive,locomotor behavior defective,feeding behavior defective,partially lethal - majority die,some die during embryonic stage,viable,good,visible,lethal,semidominant" "pigment cell,eye" FBgn0032884 Pomp Pomp http://flybase.net/reports/FBgn0032884.html protein_coding_gene "0006508=proteolysis, 0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0032436=positive regulation of proteasomal ubiquitin-dependent protein catabolic process, 0008283=cell proliferation, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" 0000502=proteasome complex "pomp, maturase, POMP, 38E.20, 20S maturase, UMP1, Proteosome maturation protein, CG9324" IPR008012=Proteasome maturation factor UMP1 CG9324 16-Dec-15 2015_12 ENSDARG00000032296(zgc:92775) ENSXETG00000026990(TGas049e06.1) ENSMUSG00000029649(Pomp) ENSG00000132963(POMP) DRSC03201 I -3.945383447 -4.010691618 -1.473379134 -1.069049473 0.929175266 0.859726008 FBgn0037297 CG1116 http://flybase.net/reports/FBgn0037297.html FBgn0062084 protein_coding_gene "anon-WO0118547.337, Rgp1" IPR014848=Reduced growth phenotype protein 1 CG1116 16-Dec-15 2015_12 ENSDARG00000006545(rgp1) WBGene00010815(M01F1.9) ENSXETG00000013212(TNeu006e17.1) ENSMUSG00000028468(Rgp1) ENSG00000107185(RGP1) "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0053891 His4:CG33891 His4:CG33891 http://flybase.net/reports/FBgn0053891.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33891 "IPR009072=Histone-fold, IPR019809=Histone H4, conserved site, IPR001951=Histone H4" CG33891 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0022700 Cht4 Chitinase 4 http://flybase.net/reports/FBgn0022700.html "FBgn0034581, FBgn0047078" protein_coding_gene "0008061=chitin binding, 0004568=chitinase activity" "0005975=carbohydrate metabolic process, 0006036=cuticle chitin catabolic process, 0006032=chitin catabolic process" 0005615=extracellular space "CG3986, DmCHT4, CHT4, BcDNA:RE62779" "IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain, IPR011583=Chitinase II, IPR001579=Glycoside hydrolase, chitinase active site, IPR029070=Chitinase insertion domain, IPR017853=Glycoside hydrolase superfamily, IPR002557=Chitin binding domain" CG3986 16-Dec-15 2015_12 "ENSDARG00000009612(zgc:55406),ENSDARG00000031586(zgc:55941),ENSDARG00000008541(zgc:65788),ENSDARG00000070962(zgc:173927),ENSDARG00000027768(zgc:63792),ENSDARG00000046129(zgc:56053)" YDR371W(CTS2) "ENSMUSG00000062778(Chia),ENSMUSG00000043873(Bclp2),ENSMUSG00000040809(Chi3l3),ENSMUSG00000063779(Chi3l4),ENSMUSG00000027902(BC051070),ENSMUSG00000026450(Chit1),ENSMUSG00000074340(Ovgp1)" "ENSG00000134216(CHIA),ENSG00000133063(CHIT1),ENSG00000064886(CHI3L2),ENSG00000133048(CHI3L1),ENSG00000085465(OVGP1)" "partially lethal - majority die,some die during pupal stage" DRSC04603 I -1.689241647 -1.058343859 -0.505796038 -0.111866183 -0.388598205 -0.436856432 FBgn0085390 Dgk Diacyl glycerol kinase http://flybase.net/reports/FBgn0085390.html "FBgn0042192, FBgn0004568, FBgn0033230" protein_coding_gene "0005509=calcium ion binding, 0004143=diacylglycerol kinase activity" "0006661=phosphatidylinositol biosynthetic process, 0007205=protein kinase C-activating G-protein coupled receptor signaling pathway, 0016310=phosphorylation, 0035556=intracellular signal transduction, 0042313=protein kinase C deactivation" "CG18654, Diacylglycerol kinase, CG1535, CG34361, dgk, DGKb, CG12820, dDGK, unnamed" "IPR029477=Diacylglycerol kinase type I, N-terminal, IPR011992=EF-hand domain pair, IPR000756=Diacylglycerol kinase, accessory domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR002048=EF-hand domain, IPR001206=Diacylglycerol kinase, catalytic domain, IPR018247=EF-Hand 1, calcium-binding site, IPR016064=NAD kinase/diacylglycerol kinase-like domain" CG34361 16-Dec-15 2015_12 "ENSDARG00000027724,ENSDARG00000060626(zgc:136759),ENSDARG00000002898" WBGene00000960(dgk-3) "ENSXETG00000005053(DGKB),ENSXETG00000009437(DGKA)" "ENSMUSG00000025357(Dgka),ENSMUSG00000036095(Dgkb),ENSMUSG00000022861(Dgkg)" "ENSG00000136267(DGKB),ENSG00000058866(DGKG),ENSG00000065357(DGKA)" " embryonic stage , adult stage " " VUM neuron

, adult brain cortex

, ventral midline

, Bolwig's organ

, mesothoracic extracoxal depressor muscle 66

, retina

, embryonic central nervous system | restricted

, indirect flight muscle

" DRSC05064 IE -1.208573964 -3.453562207 0.094114188 -4.158195097 -0.302043273 -0.552854868 FBgn0053828 His1:CG33828 His1:CG33828 http://flybase.net/reports/FBgn0053828.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33828 "IPR005818=Linker histone H1/H5, domain H15, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5" CG33828 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0015797 Rab6 Rab6 http://flybase.net/reports/FBgn0015797.html "FBgn0010648, FBgn0019647" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity, 0005515=protein binding" "0045467=R7 cell development, 0008103=oocyte microtubule cytoskeleton polarization, 0060078=regulation of postsynaptic membrane potential, 0001745=compound eye morphogenesis, 0016192=vesicle-mediated transport, 0007293=germarium-derived egg chamber formation, 0015031=protein transport, 0007411=axon guidance, 0006887=exocytosis, 0032482=Rab protein signal transduction, 0045451=pole plasm oskar mRNA localization, 0050832=defense response to fungus" "0043025=neuronal cell body, 0045202=synapse, 0005794=Golgi apparatus, 0016023=cytoplasmic membrane-bounded vesicle, 0031982=vesicle" "Dm Rab6, CG6601, AAF53168, Rab-protein 6, Rab protein 6, dRab6, wrt, drab6, warthog, 136/6, l(2)08323, DmRab6, rab6, Drab6, DRab6, O18334" "IPR003579=Small GTPase superfamily, Rab type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR001806=Small GTPase superfamily" CG6601 16-Dec-15 2015_12 "ENSDARG00000007355,ENSDARG00000034522(rab6b),ENSDARG00000029885(zgc:63637)" YLR262C(YPT6) WBGene00004270(rab-6.2) ENSXETG00000023200(rab6a) "ENSMUSG00000030704(Rab6),ENSMUSG00000032549(Rab6b)" "ENSG00000175582(RAB6A),ENSG00000154917(RAB6B),ENSG00000222014(RAB6C)" "visible,recessive,viable,immune response defective,dominant,lethal,cell non-autonomous,somatic clone,lethal - all die before end of larval stage,some die during larval stage,neurophysiology defective,wild-type" "macrochaeta,hemocyte,cell non-autonomous,somatic clone,adult head & microchaeta | somatic clone | cell non-autonomous,adult thorax & microchaeta | somatic clone | cell non-autonomous,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,interocellar bristle,scutellar bristle,scutum & macrochaeta,actin cytoskeleton & egg chamber | germ-line clone,Golgi apparatus & egg chamber | germ-line clone,microtubule cytoskeleton & egg chamber | germ-line clone,egg chamber,germline clone,photoreceptor cell R7" FBgn0039310 CG11878 http://flybase.net/reports/FBgn0039310.html protein_coding_gene CT33083 "IPR004119=Protein of unknown function DUF227, IPR015897=CHK kinase-like, IPR011009=Protein kinase-like domain" CG11878 16-Dec-15 2015_12 "WBGene00017092(E02C12.6),WBGene00010238(F58B4.5),WBGene00015963(C18B10.6),WBGene00017093(E02C12.8),WBGene00017095(E02C12.10),WBGene00021567(Y45G12C.4),WBGene00018913(F56A4.5),WBGene00010426(H37A05.2),WBGene00017094(E02C12.9),WBGene00017097(E02C12.12)" viable FBgn0067864 Patj Patj http://flybase.net/reports/FBgn0067864.html "FBgn0002177, FBgn0024246, FBgn0035274" protein_coding_gene "0005080=protein kinase C binding, 0032033=myosin II light chain binding" "0035088=establishment or maintenance of apical/basal cell polarity, 0045176=apical protein localization, 0007163=establishment or maintenance of cell polarity, 0045186=zonula adherens assembly, 0016333=morphogenesis of follicular epithelium, 0034332=adherens junction organization, 0035509=negative regulation of myosin-light-chain-phosphatase activity, 0045196=establishment or maintenance of neuroblast polarity, 0045494=photoreceptor cell maintenance, 0035209=pupal development, 0001736=establishment of planar polarity, 0016334=establishment or maintenance of polarity of follicular epithelium, 0007043=cell-cell junction assembly, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0002009=morphogenesis of an epithelium, 0034334=adherens junction maintenance, 0008594=photoreceptor cell morphogenesis" "0005875=microtubule associated complex, 0005635=nuclear envelope, 0005886=plasma membrane, 0005918=septate junction, 0005912=adherens junction, 0016324=apical plasma membrane, 0005737=cytoplasm, 0045179=apical cortex, 0035003=subapical complex, 0016327=apicolateral plasma membrane" "DPatj, patj, Dpatj, dpatj, Discs lost, discs lost, DLT, D-Patj, DPATJ, PatJ, dPATJ, Patj/Dlt, CG12021, discslost, PATJ, Dlt, BcDNA:LD22238, dlt:discs lost, Discs Lost, dPatj, PaTJ, dlt" "IPR004172=L27 domain, IPR001478=PDZ domain" CG12021 16-Dec-15 2015_12 ENSXETG00000011680(LNX1) "ENSG00000172349(IL16),ENSG00000133401(PDZD2)" pupal stage photoreceptor cell stalk | apical

"lethal,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,germline clone,cell polarity defective,somatic clone,visible" "embryonic/first instar larval cuticle,follicle cell,somatic clone,ectoderm,photoreceptor,pupa,head,pupal thorax,imaginal disc" FBgn0053829 His2A:CG33829 His2A:CG33829 http://flybase.net/reports/FBgn0053829.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33829 "IPR002119=Histone H2A, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33829 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0053819 His1:CG33819 His1:CG33819 http://flybase.net/reports/FBgn0053819.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33819 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5, IPR005818=Linker histone H1/H5, domain H15" CG33819 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0039293 CG11851 http://flybase.net/reports/FBgn0039293.html protein_coding_gene 0000030=mannosyltransferase activity 0006486=protein glycosylation 0012505=endomembrane system "unnamed, dAlg9" IPR005599=GPI mannosyltransferase CG11851 16-Dec-15 2015_12 ENSDARG00000012840(alg9) YNL219C(ALG9) WBGene00007556(C14A4.3) ENSXETG00000010169(FDXACB1) ENSMUSG00000032059(Alg9) ENSG00000086848(ALG9) viable DRSC14407 K -0.204322353 -0.455114228 0.297194715 1.497654701 2.0975499 0.3926273 FBgn0051548 CG31548 http://flybase.net/reports/FBgn0051548.html "FBgn0037355, FBgn0064831" protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "BcDNA:RH24570, CG2907" "IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG31548 16-Dec-15 2015_12 ENSDARG00000035129(zgc:101858) "YIR035C(),YIR036C(IRC24)" "WBGene00021647(Y47G6A.22),WBGene00021646(Y47G6A.21)" ENSXETG00000026045(BC076694.1) ENSMUSG00000030825(Hsd17b14) ENSG00000087076(HSD17B14) viable DRSC22640 K 0.330891797 1.236446305 1.451716451 1.454624192 -0.538102295 1.727757547 FBgn0034967 eIF-5A eIF-5A http://flybase.net/reports/FBgn0034967.html "FBgn0010483, FBgn0025208" protein_coding_gene "0043022=ribosome binding, 0045182=translation regulator activity, 0003746=translation elongation factor activity, 0003743=translation initiation factor activity" "0006413=translational initiation, 0045901=positive regulation of translational elongation, 0045905=positive regulation of translational termination, 0035220=wing disc development, 0048102=autophagic cell death, 0006452=translational frameshifting, 0032504=multicellular organism reproduction, 0035071=salivary gland cell autophagic cell death" 0005829=cytosol "Eukaryotic translation factor 5A, eukaryotic initiation factor 5A, eIF5A, 1296, unnamed, anon-fast-evolving-2H10, eIF5a, anon-EST:fe2H10, CG3186, l(2)01296, chr2R:19566878..19566998" "IPR001884=Translation elongation factor IF5A, IPR014722=Ribosomal protein L2 domain 2, IPR012340=Nucleic acid-binding, OB-fold, IPR020189=Translation elongation factor, IF5A C-terminal, IPR008991=Translation protein SH3-like domain, IPR019769=Translation elongation factor, IF5A, hypusine site" CG3186 16-Dec-15 2015_12 "ENSDARG00000056186(eif5a2),ENSDARG00000017235(eif5a)" "YEL034W(HYP2),YJR047C(ANB1)" "WBGene00002064(iff-1),WBGene00002065(iff-2)" ENSXETG00000026436(eif5a) "ENSMUSG00000078812(Eif5a),ENSMUSG00000043618,ENSMUSG00000050192(Eif5a2)" "ENSG00000132507(EIF5A),ENSG00000163577(EIF5A2)" "lethal,recessive,decreased cell size" "embryonic/larval fat body,wing cell,macrochaeta" DRSC04681 I -1.299462514 1.570271148 0.90889297 -1.175657152 0.239886116 0.200399905 FBgn0262125 Sec23 Sec23 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0262125.html "FBgn0001178, FBgn0037357, FBgn0011441" protein_coding_gene "0005096=GTPase activator activity, 0008270=zinc ion binding" "0016203=muscle attachment, 0034394=protein localization to cell surface, 0035293=chitin-based larval cuticle pattern formation, 0048081=positive regulation of cuticle pigmentation, 0006888=ER to Golgi vesicle-mediated transport, 0003331=positive regulation of extracellular matrix constituent secretion, 0008363=larval chitin-based cuticle development, 0030011=maintenance of cell polarity, 0043547=positive regulation of GTPase activity, 0007029=endoplasmic reticulum organization, 0040003=chitin-based cuticle development, 0035149=lumen formation, open tracheal system, 0003400=regulation of COPII vesicle coating, 0022409=positive regulation of cell-cell adhesion, 0071711=basement membrane organization, 0050775=positive regulation of dendrite morphogenesis, 0008360=regulation of cell shape, 0007030=Golgi organization, 0072661=protein targeting to plasma membrane, 0048812=neuron projection morphogenesis" "0030134=ER to Golgi transport vesicle, 0030127=COPII vesicle coat, 0005795=Golgi stack, 0070971=endoplasmic reticulum exit site, 0005783=endoplasmic reticulum" "Haunted, Sec23p, dSec23p, Sec23A, dsec23p, dendritic arbor reduction 2, coat protein II, Sec23, SEC23, haunted, hau, CG1250, dSec23, dar2, dsec23, COPII, sec23" "IPR007123=Gelsolin-like domain, IPR029006=ADF-H/Gelsolin-like domain, IPR006896=Sec23/Sec24, trunk domain, IPR006895=Zinc finger, Sec23/Sec24-type, IPR012990=Sec23/Sec24 beta-sandwich, IPR006900=Sec23/Sec24, helical domain, IPR002035=von Willebrand factor, type A" CG1250 16-Dec-15 2015_12 "ENSDARG00000016636(sec23a),ENSDARG00000019360(sec23b)" YPR181C(SEC23) WBGene00004754(sec-23) ENSXETG00000000783(sec23b) "ENSMUSG00000020986(Sec23a),ENSMUSG00000027429(Sec23b)" "ENSG00000100934(SEC23A),ENSG00000101310(SEC23B)" DRSC12387 E -0.240496034 0.187126173 1.525756143 0.053635107 0.475701515 -0.148150551 FBgn0030558 CG1461 http://flybase.net/reports/FBgn0030558.html protein_coding_gene "0004838=L-tyrosine:2-oxoglutarate aminotransferase activity, 0030170=pyridoxal phosphate binding" "0009072=aromatic amino acid family metabolic process, 0009058=biosynthetic process" "IPR004838=Aminotransferases, class-I, pyridoxal-phosphate-binding site, IPR015424=Pyridoxal phosphate-dependent transferase, IPR005958=Tyrosine/nicotianamine aminotransferase, IPR004839=Aminotransferase, class I/classII, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR005957=Tyrosine aminotransferase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG1461 16-Dec-15 2015_12 ENSDARG00000069630(tat) WBGene00009628(tatn-1) ENSXETG00000023416(tat) ENSMUSG00000001670(Tat) ENSG00000198650(TAT) FBgn0035499 Chd64 Chd64 http://flybase.net/reports/FBgn0035499.html FBgn0025973 protein_coding_gene "0070594=juvenile hormone response element binding, 0003779=actin binding, 0005515=protein binding" "0035626=juvenile hormone mediated signaling pathway, 0006939=smooth muscle contraction" 0005865=striated muscle thin filament "CG-14996, CG14996, CT34849, anon-EST:Liang-1.80, clone 1.80" "IPR000557=Calponin repeat, IPR003096=Smooth muscle protein/calponin, IPR001715=Calponin homology domain" CG14996 16-Dec-15 2015_12 "ENSDARG00000029856(cnn3b),ENSDARG00000008359(cnn3a),ENSDARG00000035858(cnn2),ENSDARG00000010365(LOC572250),ENSDARG00000017193(LOC567396)" YOR367W(SCP1) WBGene00000777(cpn-1) "ENSXETG00000018919(cnn3),ENSXETG00000027225(tagln2),ENSXETG00000016732(cnn1),ENSXETG00000003286(cnn2),ENSXETG00000003757(tagln)" "ENSMUSG00000026547(Tagln2),ENSMUSG00000022658(Tagln3),ENSMUSG00000032085(Tagln)" "ENSG00000158710(TAGLN2),ENSG00000144834(TAGLN3),ENSG00000149591(TAGLN)" "viable,sleep defective,partially lethal - majority die,some die during pupal stage" FBgn0010380 AP-1-2ë_ "Adaptor Protein complex 1/2, ë_ subunit" http://flybase.net/reports/FBgn0010380.html protein_coding_gene 0008565=protein transporter activity "0016183=synaptic vesicle coating, 0006901=vesicle coating, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0007269=neurotransmitter secretion, 0048749=compound eye development" "0030122=AP-2 adaptor complex, 0008021=synaptic vesicle, 0030121=AP-1 adaptor complex, 0005886=plasma membrane, 0005802=trans-Golgi network, 0030119=AP-type membrane coat adaptor complex, 0030136=clathrin-coated vesicle, 0005905=coated pit, 0030135=coated vesicle" "Beta-adaptin, apl2, BAP, CG12532, Bap, AP-1/2beta, beta-adaptin, BAD1, AP2beta2, AP-1-2beta, apl1, bap, Beta Adaptin, AP-beta1, Beta Adaptin Drosophila 1, beta1/2, AP-1beta1, AP1beta1, cg12532, AP-2beta" "IPR026739=AP complex subunit beta, IPR016342=AP-1, 2,4 complex subunit beta, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR013037=Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain, IPR015151=Beta-adaptin appendage, C-terminal subdomain, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR013041=Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR008152=Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR009028=Coatomer/calthrin adaptor appendage, C-terminal subdomain, IPR012295=Beta2-adaptin/TBP, C-terminal domain" CG12532 16-Dec-15 2015_12 ENSDARG00000020621(ap1b1) YKL135C(APL2) WBGene00000160(apb-1) "ENSXETG00000016417(AP1B1),ENSXETG00000013480(ap2b1)" "ENSMUSG00000009090(Ap1b1),ENSMUSG00000035152(Ap2b1)" "ENSG00000100280(AP1B1),ENSG00000006125(AP2B1)" "lethal - all die before end of pupal stage,some die during pupal stage,lethal" eye DRSC19336 I -0.816838589 1.782481382 -0.26857113 0.621565412 -0.080638364 -0.080004144 FBgn0036928 Tom20 Translocase of outer membrane 20 http://flybase.net/reports/FBgn0036928.html FBgn0062160 protein_coding_gene 0015450=P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0006626=protein targeting to mitochondrion "0005739=mitochondrion, 0005742=mitochondrial outer membrane translocase complex" "TOM20, dtom20, CG7654, TOM 20, anon-WO0118547.225" "IPR023392=Mitochondrial outer membrane translocase complex, subunit Tom20 domain, IPR002056=Protein import receptor MAS20, IPR022422=Protein import receptor MAS20, metazoan" CG7654 16-Dec-15 2015_12 ENSDARG00000025132(tomm20a) YGR082W(TOM20) WBGene00009092(tomm-20) ENSXETG00000024650(tomm20) ENSMUSG00000058779(Tomm20) ENSG00000173726(TOMM20) "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0036967 CG6597 http://flybase.net/reports/FBgn0036967.html protein_coding_gene "IPR005176=Potentiating neddylation domain, IPR014764=Defective-in-cullin neddylation protein" CG6597 16-Dec-15 2015_12 "ENSDARG00000044478(dcun1d5),ENSDARG00000052338(dcun1d4)" YLR128W(DCN1) ENSXETG00000022216(MGC2714) "ENSMUSG00000051674(Dcun1d4),ENSMUSG00000032002(Dcun1d5)" "ENSG00000109184(DCUN1D4),ENSG00000137692(DCUN1D5)" viable FBgn0046332 gskt gasket http://flybase.net/reports/FBgn0046332.html "FBgn0043075, FBgn0045206, FBgn0045820, FBgn0051003, FBgn0065002" protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0006468=protein phosphorylation, 0008584=male gonad development, 0048232=male gamete generation" 0005737=cytoplasm "BEST:GH16447, BcDNA:AT21229, GSK3b, NGSK, CG31003, NEST:bs22e06, Dm Gskt, CG11338, Gskt, CT4237, mjl, Gsk3b, mojoless" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain" CG31003 16-Dec-15 2015_12 "ENSDARG00000017803(gsk3b),ENSDARG00000052468(LOC557882),ENSDARG00000015681(gsk3a),ENSDARG00000029501(si:ch211-39e15.2)" "YMR139W(RIM11),YDL079C(MRK1)" WBGene00001746(gsk-3) ENSXETG00000018019(GSK3B) "ENSMUSG00000022812(Gsk3b),ENSMUSG00000057177(Gsk3a)" "ENSG00000082701(GSK3B),ENSG00000105723(GSK3A)" "viable,visible,male sterile germline-dependent" "trichogen cell,wing margin" FBgn0033277 CG14760 http://flybase.net/reports/FBgn0033277.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP120 "IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain, IPR000859=CUB domain" CG14760 16-Dec-15 2015_12 "ENSDARG00000060754(LOC557248),ENSDARG00000061173(st14a),ENSDARG00000062758" ENSXETG00000017920(BC076994.1) "ENSMUSG00000031995(St14),ENSMUSG00000016942(Tmprss6),ENSMUSG00000033177(Tmprss7)" "ENSG00000149418(ST14),ENSG00000187045(TMPRSS6),ENSG00000176040(TMPRSS7)" viable FBgn0010352 Nc73EF Neural conserved at 73EF http://flybase.net/reports/FBgn0010352.html "FBgn0036682, FBgn0062089" protein_coding_gene "0004591=oxoglutarate dehydrogenase (succinyl-transferring) activity, 0030976=thiamine pyrophosphate binding" 0006099=tricarboxylic acid cycle "0005875=microtubule associated complex, 0009353=mitochondrial oxoglutarate dehydrogenase complex" "Nc73eF, CG11661, E1, anon-WO0118547.329, FBgn0036682, Neural conserved at 73KF, alpha-ketoglutarate dehydrogenase E1 subunit, 141810_at" "IPR005475=Transketolase-like, pyrimidine-binding domain, IPR029061=Thiamin diphosphate-binding fold, IPR011603=2-oxoglutarate dehydrogenase E1 component, IPR001017=Dehydrogenase, E1 component" CG11661 16-Dec-15 2015_12 ENSDARG00000034270(ogdh) YIL125W(KGD1) WBGene00020679(T22B11.5) "ENSXETG00000018997(OGDH),ENSXETG00000005613(OGDHL)" "ENSMUSG00000020456(Ogdh),ENSMUSG00000021913(Ogdhl)" "ENSG00000105953(OGDH),ENSG00000197444(OGDHL)" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0010408 RpS9 Ribosomal protein S9 http://flybase.net/reports/FBgn0010408.html protein_coding_gene "0003735=structural constituent of ribosome, 0019843=rRNA binding" "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization" "0005730=nucleolus, 0005840=ribosome, 0022627=cytosolic small ribosomal subunit, 0000228=nuclear chromosome, 0005829=cytosol, 0005737=cytoplasm" "unnamed, S9, CG3395, RpL11, chr3L:9483841..9483937, Rp S9, chr3L:9484246..9484474" "IPR001912=Ribosomal protein S4/S9, N-terminal, IPR002942=RNA-binding S4 domain, IPR018079=Ribosomal protein S4, conserved site, IPR022801=Ribosomal protein S4/S9, IPR005710=Ribosomal protein S4/S9, eukaryotic/archaeal" CG3395 16-Dec-15 2015_12 ENSDARG00000011405(LOC100329314) "YBR189W(RPS9B),YPL081W(RPS9A)" WBGene00004478(rps-9) ENSXETG00000009030(rps9) ENSMUSG00000006333(Rps9) ENSG00000170889(RPS9) "viable,fertile,Minute" DRSC11273 EK -0.562962742 0.04905849 2.88019009 -4.012587506 1.31556559 4.6632144 FBgn0039812 CG15548 http://flybase.net/reports/FBgn0039812.html protein_coding_gene CG15548 16-Dec-15 2015_12 viable DRSC15086 E 0.33824122 -0.062562998 0.11468095 -1.54741454 0.469707313 0.034597307 FBgn0265296 Dscam2 Down syndrome cell adhesion molecule 2 http://flybase.net/reports/FBgn0265296.html "FBgn0263218, FBgn0250790, FBgn0259141, FBgn0052387, FBgn0035747, FBgn0035748, FBgn0035749, FBgn0063359, FBgn0052389, FBgn0035746" protein_coding_gene 0042802=identical protein binding "0048812=neuron projection morphogenesis, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules" 0005887=integral component of plasma membrane "BcDNA:AT03867, CG32389, CG8618, Dscam-like, CT14580, CG14828, CG42256, CG32387, CG17742, CT14584, CT34644, CG8619" "IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III" CG42256 16-Dec-15 2015_12 "ENSDARG00000024865(dscam),ENSDARG00000028118(LOC565371),ENSDARG00000057052(LOC100002762)" ENSXETG00000003741(DSCAML1) "ENSMUSG00000050272(Dscam),ENSMUSG00000032087(Dscaml1)" "ENSG00000171587(DSCAM),ENSG00000177103(DSCAML1)" DRSC22526 I 2.005726148 0.041265334 1.024829205 -0.119416755 -0.580020531 0.332182177 FBgn0026439 Eaat1 Excitatory amino acid transporter 1 http://flybase.net/reports/FBgn0026439.html FBgn0025880 protein_coding_gene "0015183=L-aspartate transmembrane transporter activity, 0017153=sodium:dicarboxylate symporter activity, 0015501=glutamate:sodium symporter activity, 0005313=L-glutamate transmembrane transporter activity" "0015810=aspartate transport, 0008340=determination of adult lifespan, 0015813=L-glutamate transport, 0007268=synaptic transmission, 0014853=regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction, 0006835=dicarboxylic acid transport, 0008345=larval locomotory behavior" "0005886=plasma membrane, 0016021=integral component of membrane, 0031594=neuromuscular junction, 0043005=neuron projection, 0043195=terminal bouton" "glutamate transporter, Dglt-1, excitatory amino acid transporter 1, dEaat1, dEAAT, sodium-excitatory-glutamate-cotransporter, sodium-dependent glutamate transporter, EAAT1, eaat1, Drosophila glutamate transporter-1, dEAAT1, EAAT, Dglut-1, AF001784, CG3747, sodium-dependent excitatory amino acid transporter 1" "IPR018107=Sodium:dicarboxylate symporter, conserved site, IPR001991=Sodium:dicarboxylate symporter" CG3747 16-Dec-15 2015_12 "ENSDARG00000026218(slc1a3a),ENSDARG00000043148(LOC556181),ENSDARG00000010096(slc1a6),ENSDARG00000020212(slc1a1),ENSDARG00000032465(slc1a7l),ENSDARG00000016465(slc1a5),ENSDARG00000034628(slc1a8a),ENSDARG00000034940(slc1a7)" "ENSXETG00000006083(SLC1A3),ENSXETG00000021879(SLC1A6),ENSXETG00000008068(SLC1A7),ENSXETG00000011685(SLC1A1)" "ENSMUSG00000005360(Slc1a3),ENSMUSG00000005357(Slc1a6),ENSMUSG00000008932(Slc1a7),ENSMUSG00000024935(Slc1a1)" "ENSG00000079215(SLC1A3),ENSG00000105143(SLC1A6),ENSG00000162383(SLC1A7),ENSG00000106688(SLC1A1)" " larval stage | third instar , embryonic stage | stage 15-16 , adult stage , embryonic stage | stage 17 , embryonic stage | stage 16-17 " " larval optic lobe

, ventral nerve cord

, adult head

, midline glial cell

, medulla cortex

, embryonic brain

, interneuron &&of larval brain

, motor neuron &&of ventral nerve cord

, motor neuron

, CNS glial cell | subset

, ventral nerve cord

segmentally repeated " L | third instar neuropil compartment &&of larval central nervous system "locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,neurophysiology defective,touch sensitivity defective,flight defective" "aCC neuron,RP2 motor neuron,neuropil,dopaminergic neuron,synapseEaat1.PR,adult neuromuscular junction,neuromuscular junctionEaat1.PR" FBgn0037518 CG2641 http://flybase.net/reports/FBgn0037518.html protein_coding_gene "IPR014756=Immunoglobulin E-set, IPR011021=Arrestin-like, N-terminal, IPR011022=Arrestin C-terminal-like domain" CG2641 16-Dec-15 2015_12 "ENSDARG00000052690(arrdc3),ENSDARG00000036028(zgc:92034),ENSDARG00000020761(arrdc2),ENSDARG00000036107(txnip),ENSDARG00000070000(LOC100329369),ENSDARG00000070001,ENSDARG00000053159(zgc:110626),ENSDARG00000039443(zgc:110353)" "ENSMUSG00000074794(Arrdc3),ENSMUSG00000002910(Arrdc2),ENSMUSG00000042659(Arrdc4),ENSMUSG00000038393(Txnip)" ENSG00000197070(ARRDC1) viable FBgn0053816 His1:CG33816 His1:CG33816 http://flybase.net/reports/FBgn0053816.html protein_coding_gene 0003677=DNA binding "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0005634=nucleus, 0000786=nucleosome" CG33816 "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR005819=Histone H5, IPR005818=Linker histone H1/H5, domain H15" CG33816 16-Dec-15 2015_12 "ENSDARG00000051727(LOC100333895),ENSDARG00000032637(LOC560910),ENSDARG00000051771,ENSDARG00000051773,ENSDARG00000051718(LOC573073),ENSDARG00000051735,ENSDARG00000052441,ENSDARG00000068041,ENSDARG00000068048,ENSDARG00000068045,ENSDARG00000031303,ENSDARG00000051777,ENSDARG00000058479(zgc:110425),ENSDARG00000058524,ENSDARG00000035519(zgc:110380),ENSDARG00000055289,ENSDARG00000038559(zgc:65861)" "WBGene00001853(hil-2),WBGene00001854(hil-3),WBGene00001898(his-24),WBGene00001857(hil-6),WBGene00001855(hil-4),WBGene00001856(hil-5)" "ENSXETG00000024975(),ENSXETG00000015967(h1f0),ENSXETG00000027850(),ENSXETG00000027143(),ENSXETG00000027190(),ENSXETG00000027195(),ENSXETG00000027174(),ENSXETG00000020820(),ENSXETG00000026079(),ENSXETG00000027962(),ENSXETG00000025392(),ENSXETG00000026306(TGas008a06.1),ENSXETG00000027191()" "ENSMUSG00000052565(Hist1h1d),ENSMUSG00000058773(Hist1h1b),ENSMUSG00000051627(Hist1h1e),ENSMUSG00000036181(Hist1h1c),ENSMUSG00000049539(Hist1h1a),ENSMUSG00000036211(Hist1h1t)" "ENSG00000168298(HIST1H1E),ENSG00000184357(HIST1H1B),ENSG00000124575(HIST1H1D),ENSG00000187837(HIST1H1C),ENSG00000124610(HIST1H1A),ENSG00000187475(HIST1H1T)" FBgn0027491 Cdk5ë± Cdk5 activator-like protein http://flybase.net/reports/FBgn0027491.html FBgn0026195 protein_coding_gene 0016534=cyclin-dependent protein kinase 5 activator activity "0070059=intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, 0035011=melanotic encapsulation of foreign target, 0008344=adult locomotory behavior, 0007409=axonogenesis, 0008045=motor neuron axon guidance, 0006468=protein phosphorylation, 0008340=determination of adult lifespan" "0030424=axon, 0030425=dendrite, 0016533=cyclin-dependent protein kinase 5 holoenzyme complex, 0043025=neuronal cell body, 0030426=growth cone" "dCdk5alpha, P35, CG5387, Dp35, p35-21C, Cdk5a, Cdk5alpha, p35-31C, D-p35, p25, p35" "IPR013763=Cyclin-like, IPR004944=Cyclin-dependent kinase 5 activator" CG5387 16-Dec-15 2015_12 "ENSDARG00000036105(si:dkeyp-92c9.2),ENSDARG00000045087(cdk5r1b),ENSDARG00000037916(cdk5r1a)" WBGene00011955(cdka-1) "ENSXETG00000020364(),ENSXETG00000003191(CDK5R1)" ENSMUSG00000048895(Cdk5r1) ENSG00000171450(CDK5R2) "short lived,recessive,neuroanatomy defective,locomotor behavior defective,viable,fertile,lethal,partially lethal - majority die,visible" "eye,segmental nerve branch SNa of A1-7,intersegmental nerve branch ISNb of A1-7,transverse nerve,motor neuron,mesothoracic tergum" FBgn0065032 Arpc3B "Actin-related protein 2/3 complex, subunit 3B" http://flybase.net/reports/FBgn0065032.html "FBgn0030818, FBgn0062850" protein_coding_gene "0005200=structural constituent of cytoskeleton, 0003779=actin binding" "0007015=actin filament organization, 0034314=Arp2/3 complex-mediated actin nucleation" 0005885=Arp2/3 protein complex "Arpc3B, Arpc3, CG8936, BcDNA:SD24339, Arpc3b, P21-ARC" IPR007204=Actin-related protein 2/3 complex subunit 3 CG8936 16-Dec-15 2015_12 ENSDARG00000057882(arpc3) YLR370C(ARC18) WBGene00000203(arx-5) ENSXETG00000020940(ARPC3) ENSMUSG00000029465(Arpc3) ENSG00000111229(ARPC3) " oogenesis stage , adult stage | female " " nurse cell ring canal

, ovary

" "viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053909 His4:CG33909 His4:CG33909 http://flybase.net/reports/FBgn0053909.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006333=chromatin assembly or disassembly, 0006334=nucleosome assembly" "0000786=nucleosome, 0005634=nucleus" CG33909 "IPR009072=Histone-fold, IPR001951=Histone H4, IPR019809=Histone H4, conserved site" CG33909 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0053874 His2B:CG33874 His2B:CG33874 http://flybase.net/reports/FBgn0053874.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33874 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000558=Histone H2B" CG33874 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0034733 CG4752 http://flybase.net/reports/FBgn0034733.html protein_coding_gene 0017168=5-oxoprolinase (ATP-hydrolyzing) activity "IPR002821=Hydantoinase/oxoprolinase, IPR008040=Hydantoinaseoxoprolinase, N-terminal, IPR003692=Hydantoinase B/oxoprolinase" CG4752 16-Dec-15 2015_12 ENSDARG00000045123 YKL215C(OXP1) WBGene00021430(Y38F2AR.12) ENSXETG00000007139(OPLAH) ENSMUSG00000022562(Oplah) ENSG00000178814(OPLAH) "viable,fertile" DRSC04486 I 1.357837881 2.622022862 0.351124353 0.994816415 -0.361937741 0.584638702 FBgn0032536 Ance-3 Ance-3 http://flybase.net/reports/FBgn0032536.html "FBgn0028937, FBgn0051766, FBgn0051843" protein_coding_gene "0008241=peptidyl-dipeptidase activity, 0008237=metallopeptidase activity" 0006508=proteolysis "0016021=integral component of membrane, 0016020=membrane" "ance-3, CG31843, CG31766, CG17988, CT40163, DS00180.5, BG:DS00180.5" "IPR001548=Peptidase M2, peptidyl-dipeptidase A" CG17988 16-Dec-15 2015_12 ENSDARG00000016918(ace2) WBGene00000039(acn-1) ENSMUSG00000015405(Ace2) ENSG00000130234(ACE2) viable DRSC02649 K -1.196561988 -0.171456922 0.267623732 -0.251603748 0.569999257 1.580791178 FBgn0003356 Jon99Cii Jonah 99Cii http://flybase.net/reports/FBgn0003356.html "FBgn0001288, FBgn0011833, FBgn0051034" protein_coding_gene "0004252=serine-type endopeptidase activity, 0008236=serine-type peptidase activity" "0006508=proteolysis, 0007586=digestion" "SER1, Jonah 99C Alpha, Jon99Calpha, CG31034, Jon99C1, Jon99Cbeta, 99Calpha, Jon99Cbetaii, Jon99B, Jon99C2, Serine protease 5, Ser99Da, Jon99C, Jonah 99C Beta, Ser5, Serl, Ser1, Serine protease 1, JonC, Jon99Calphai, CG7877, SP122" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG31034 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" FBgn0002707 mei-9 meiotic 9 http://flybase.net/reports/FBgn0002707.html protein_coding_gene "0046982=protein heterodimerization activity, 0003697=single-stranded DNA binding, 0000014=single-stranded DNA endodeoxyribonuclease activity, 0004520=endodeoxyribonuclease activity, 0005515=protein binding" "0007143=female meiotic division, 0006296=nucleotide-excision repair, DNA incision, 5'-to lesion, 0000710=meiotic mismatch repair, 0016321=female meiosis chromosome segregation, 0006302=double-strand break repair, 0006974=cellular response to DNA damage stimulus, 0045132=meiotic chromosome segregation, 0006298=mismatch repair, 0000724=double-strand break repair via homologous recombination, 0007095=mitotic G2 DNA damage checkpoint, 0006310=DNA recombination, 0000712=resolution of meiotic recombination intermediates, 0007131=reciprocal meiotic recombination, 0006289=nucleotide-excision repair" "0005634=nucleus, 0043234=protein complex, 0000110=nucleotide-excision repair factor 1 complex" "xpf/mei-9, Rad1p, mus110, mei9, MEI-9, DhR1, Mei-9, DmXPF, mus(1)110, meiotic-9, CG3697" "IPR006167=DNA repair protein, IPR010994=RuvA domain 2-like, IPR011335=Restriction endonuclease type II-like, IPR020819=DNA repair nuclease, XPF-type/Helicase, IPR006166=ERCC4 domain" CG3697 16-Dec-15 2015_12 ENSDARG00000014161(ercc4) YPL022W(RAD1) WBGene00008140(C47D12.8) ENSXETG00000010991(ERCC4) ENSMUSG00000022545(Ercc4) ENSG00000175595(ERCC4) "radiation sensitive,chemical sensitive,viable,fertile,meiotic cell cycle defective,female,female sterile,wild-type,mitotic cell cycle defective,recessive,DNA repair defective,female fertile,lethal,partially,short lived,increased cell death,conditional" "presumptive oocyte,mitosis & nuclear chromosome,egg chamber,eye,conditional" FBgn0267383 Ubc87F Ubiquitin conjugating enzyme 87F http://flybase.net/reports/FBgn0267383.html "FBgn0028395, FBgn0040263, FBgn0038175, FBgn0064955" protein_coding_gene 0004842=ubiquitin-protein transferase activity 0000209=protein polyubiquitination "Ubc87Fb, BcDNA:GH25305, Ubc87F, UBC, CG9602, AT76, 83A, Ubiquitin conjugating enzyme 87Fb" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site" CG9602 16-Dec-15 2015_12 "ENSDARG00000015292(ube2g2),ENSDARG00000069527(ube2g1)" WBGene00006704(ubc-7) ENSXETG00000026172(ube2g1) FBgn0032076 CG9510 http://flybase.net/reports/FBgn0032076.html "FBgn0043835, FBgn0053085, FBtr0079791, FBpp0079391, FBtr0079792, FBpp0079392, FBtr0079793, FBpp0079393" protein_coding_gene 0004056=argininosuccinate lyase activity 0042450=arginine biosynthetic process via ornithine "CG33085, BEST:GH06087, gh06087" "IPR009049=Argininosuccinate lyase, IPR020557=Fumarate lyase, conserved site, IPR000362=Fumarate lyase family, IPR022761=Fumarate lyase, N-terminal, IPR029419=Argininosuccinate lyase, C-terminal, IPR024083=Fumarase/histidase, N-terminal, IPR008948=L-Aspartase-like" CG9510 16-Dec-15 2015_12 ENSDARG00000033361(LOC100333289) YHR018C(ARG4) ENSXETG00000000846() ENSMUSG00000025533(Asl) ENSG00000169910 "viable,fertile" FBgn0015039 Cyp9b2 Cytochrome P450-9b2 http://flybase.net/reports/FBgn0015039.html FBgn0043831 protein_coding_gene "0005506=iron ion binding, 0004497=monooxygenase activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0009055=electron carrier activity, 0020037=heme binding" 0055114=oxidation-reduction process "0016020=membrane, 0043231=intracellular membrane-bounded organelle" "P-450 Cyp9b2, cytochrome P450, BEST:GH08116, cyp9b2, P-450, fly plexin a, 9b2, CG4486, P450" "IPR001128=Cytochrome P450, IPR002403=Cytochrome P450, E-class, group IV, IPR017972=Cytochrome P450, conserved site" CG4486 16-Dec-15 2015_12 ENSDARG00000045627(cyp3a65) YHR007C(ERG11) "WBGene00008810(cyp-13A12),WBGene00008809(cyp-13A11),WBGene00014254(cyp-13A10),WBGene00011677(cyp-13A1),WBGene00011674(cyp-13A8),WBGene00010606(cyp-13B2),WBGene00008519(cyp-13B1)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "ENSMUSG00000056035(Cyp3a11),ENSMUSG00000075551(Cyp3a41a),ENSMUSG00000075552(Cyp3a41b),ENSMUSG00000054417(Cyp3a44),ENSMUSG00000038656(Cyp3a16),ENSMUSG00000029727(Cyp3a13),ENSMUSG00000029630(Cyp3a25),ENSMUSG00000070419(Cyp3a57),ENSMUSG00000061292(Cyp3a59)" "ENSG00000160868(CYP3A4),ENSG00000160870(CYP3A7),ENSG00000106258(CYP3A5),ENSG00000021461(CYP3A43),ENSG00000059377(TBXAS1)" FBgn0015774 NetB Netrin-B http://flybase.net/reports/FBgn0015774.html protein_coding_gene "0008347=glial cell migration, 2000289=regulation of photoreceptor cell axon guidance, 0016200=synaptic target attraction, 0070983=dendrite guidance, 0008045=motor neuron axon guidance, 0007411=axon guidance, 0008039=synaptic target recognition, 0007432=salivary gland boundary specification" 0005578=proteinaceous extracellular matrix "D-netrin-B, netrin-B, netrin B, NETRIN, net, NETB, netrinB, netrin, CT29512, Netrin, D-netrin, NetrinB, netB, CG10521, Netrin B" "IPR001134=Netrin domain, IPR008993=Tissue inhibitor of metalloproteinases-like, OB-fold, IPR008211=Laminin, N-terminal, IPR018933=Netrin module, non-TIMP type, IPR008979=Galactose-binding domain-like, IPR002049=Laminin EGF domain" CG10521 16-Dec-15 2015_12 "ENSDARG00000033733(ntn1a),ENSDARG00000022531(ntn1b)" WBGene00006746(unc-6) "ENSXETG00000019519(NTN1),ENSXETG00000020288(NTN3),ENSXETG00000014390(NTN5)" "ENSMUSG00000020902(Ntn1),ENSMUSG00000079662(Ntn3)" "ENSG00000065320(NTN1),ENSG00000162068(NTN3)" " embryonic stage , embryonic stage | stage 12-14 , embryonic stage | stage 13,14 , embryonic stage | stage 14 , embryonic stage | stage 12-17 , embryonic stage | early , embryonic stage | stage 13-17 , embryonic stage -- adult stage " " embryonic brain | restricted

, midline glial cell

, dorsal mesothoracic disc | precursor

, abdominal 2--7 dorsal acute muscle 2

, visceral mesoderm

, somatic mesoderm | restricted

, mesectoderm

, mesoderm anlage

, MP1 neuron

, abdominal 2--7 ventral longitudinal muscle 3

, abdominal 2--7 ventral longitudinal muscle 4

, neuroblast MP2

, embryonic nervous system | restricted

" " embryonic stage | stage 12-17 , embryonic stage | stage >=14 , embryonic stage , embryonic stage | stage >=12 , embryonic stage | stage 14 , embryonic stage | stage 13 " " neuron &&of embryonic nervous system

, central nervous system | restricted

, embryonic peripheral nervous system | restricted

, visceral mesoderm

, larval muscle system | restricted

, imaginal disc primordium

, embryonic/larval dorsal vessel

, eye-antennal disc primordium

, labial disc primordium

, mesectoderm

, mesoderm

, somatic mesoderm

, dorsal mesothoracic disc primordium

, chordotonal organ

, genital disc primordium

, midline glial cell

, dorsal metathoracic disc primordium

, stomatogastric nervous system

" "viable,neuroanatomy defective,visible,partially lethal - majority die,wild-type,decreased cell death,female semi-fertile" "peripheral glial cell,optic lobe,photoreceptor cell R8 stalk,intersegmental nerve branch ISNb of A1-7,wing,motor neuron | third instar larval stage,somatic clone,transverse nerve,segmental nerve,optic nerve,photoreceptor cell & axonGMR.PF,photoreceptor cell & axon,lamina,pCC neuron & axonunspecified,longitudinal connective,commissure,axon-537.4,intersegmental nerve,abdominal segmental nerve,presumptive embryonic salivary gland,axonelav.PLu, -537.4" FBgn0000565 Eip71CD Ecdysone-induced protein 28/29kD http://flybase.net/reports/FBgn0000565.html FBgn0026825 protein_coding_gene 0008113=peptide-methionine (S)-S-oxide reductase activity "0030091=protein repair, 0000096=sulfur amino acid metabolic process, 0006979=response to oxidative stress, 0035071=salivary gland cell autophagic cell death, 0008340=determination of adult lifespan, 0048102=autophagic cell death, 0048812=neuron projection morphogenesis, 0055114=oxidation-reduction process, 0034599=cellular response to oxidative stress" "Eip71C, MsrA, methionine sulfoxide reductase A, Eip28/29, Methionine-S-sulfoxide reductase, methionine-S-sulfoxide reductase, Eip28 /29, methionine reductase A, Eip28, CG7266, dmsrA, DROZ60MEX, eip28/29" "IPR002569=Peptide methionine sulphoxide reductase MsrA, IPR028427=Peptide methionine sulfoxide reductase" CG7266 16-Dec-15 2015_12 "ENSDARG00000029587(si:dkey-221h15.1),ENSDARG00000055270(im:7149628)" YER042W(MXR1) WBGene00018393(msra-1) "ENSXETG00000020629(),ENSXETG00000000700()" ENSMUSG00000054733(Msra) ENSG00000175806(MSRA) " larval stage | third instar , adult stage , larval stage , adult stage && oogenesis stage " " embryonic/larval salivary gland

, adult midgut

, embryonic/larval fat body

, Malpighian tubule

, embryonic/larval hemocyte

, adult fat body

, nurse cell

, embryonic/larval anterior spiracle

, central nervous system

, embryonic/larval midgut

, lymph gland

, oocyte

, epidermis

, embryonic/larval pharynx

, embryonic/larval proventriculus | posterior

, crop

" "increased cell number,size defective,oxidative stress response defective,long lived,RU486 conditional,viable,fertile" eye FBgn0016693 Past1 Putative Achaete Scute Target 1 http://flybase.net/reports/FBgn0016693.html protein_coding_gene "0005525=GTP binding, 0005509=calcium ion binding" "0048477=oogenesis, 0008587=imaginal disc-derived wing margin morphogenesis, 0032456=endocytic recycling, 0006897=endocytosis, 0007474=imaginal disc-derived wing vein specification, 0007291=sperm individualization" "CG66148, PAST, putative achaete scute target 1, PAST-1, EH domain containing protein, Ehd, CG6148, Past-1, dEHD" "IPR000261=EH domain, IPR029947=EH domain-containing protein 1, IPR030381=Dynamin-type guanine nucleotide-binding (G) domain, IPR002048=EF-hand domain, IPR029952=EH domain-containing protein 4, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6148 16-Dec-15 2015_12 "ENSDARG00000007869(ehd3),ENSDARG00000014793(ehd1),ENSDARG00000054302(im:7147183),ENSDARG00000040362(ehd2)" WBGene00004373(rme-1) "ENSXETG00000001638(ehd1),ENSXETG00000022070(EHD3),ENSXETG00000015794(EHD4),ENSXETG00000002783(ehd2)" "ENSMUSG00000024772(Ehd1),ENSMUSG00000024065(Ehd3),ENSMUSG00000027293(Ehd4),ENSMUSG00000074364(Ehd2)" "ENSG00000110047(EHD1),ENSG00000013016(EHD3),ENSG00000103966(EHD4),ENSG00000024422(EHD2)" "viable,developmental rate defective,short lived,partially lethal - majority die,heat sensitive,semi-sterile" "testis,spermatid cyst,individualization stage spermatid,cystic bulge,ovary,oocyte,egg chamber,embryonic/larval garland cell" FBgn0037770 Art4 Arginine methyltransferase 4 http://flybase.net/reports/FBgn0037770.html protein_coding_gene "0035242=protein-arginine omega-N asymmetric methyltransferase activity, 0042054=histone methyltransferase activity, 0035241=protein-arginine omega-N monomethyltransferase activity, 0008469=histone-arginine N-methyltransferase activity" "0034969=histone arginine methylation, 0019919=peptidyl-arginine methylation, to asymmetrical-dimethyl arginine, 0016571=histone methylation" "0005634=nucleus, 0035097=histone methyltransferase complex, 0005737=cytoplasm" "arginine methyl-transferase 4, CG5358, CARMER, Coactivator Arg methyltransferase for Ecr/Usp, CARM1, Arginie methyl transferase 4, DART4, dArt 4, Carmer" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025799=Protein arginine N-methyltransferase" CG5358 16-Dec-15 2015_12 ENSDARG00000018698(carm1) ENSXETG00000009357(CARM1) ENSMUSG00000032185(Carm1) ENSG00000142453(CARM1) "cell death defective,increased cell death,conditional,viable,fertile" FBgn0039254 Nmnat Nicotinamide mononucleotide adenylyltransferase http://flybase.net/reports/FBgn0039254.html protein_coding_gene "0051082=unfolded protein binding, 0000309=nicotinamide-nucleotide adenylyltransferase activity" "0097062=dendritic spine maintenance, 0045494=photoreceptor cell maintenance, 0009435=NAD biosynthetic process" "DmNMNAT, nicotinamide mononucleotide adenyltransferase, Nmnat1, nicotinamide mononucleotide adenylyltransferase 1, nicotinamide mononucleotide adenylyl transferase 1, CG13645, dNmnat, NmnatB, nmnat, 3R4, NMNAT, nicotinamide mononucleotide adenylyltransferase, Nicotinamide mononucleotide adenylytransferase, AAL90149" "IPR005248=Probable nicotinate-nucleotide adenylyltransferase, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR004821=Cytidyltransferase-like domain" CG13645 16-Dec-15 2015_12 ENSDARG00000055893(zgc:110243) "YGR010W(NMA2),YLR328W(NMA1)" "WBGene00009176(F26H9.4),WBGene00012295(W06B3.1)" ENSXETG00000022154(nmnat1) "ENSMUSG00000028992(Nmnat1),ENSMUSG00000032456(Nmnat3)" "ENSG00000173614(NMNAT1),ENSG00000163864(NMNAT3)" "neuroanatomy defective,viable,somatic clone,phototaxis defective,neurophysiology defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "adult olfactory receptor neuron,alpha/beta Kenyon cell,somatic clone,optic cartridge,t-bar,eye,rhabdomere,ommatidium,dorsal multidendritic neuron ddaC,dendrite | somatic clone,dendrite,class III dendritic arborizing neuron,class I dendritic arborizing neuron,motor neuron,alpha/beta Kenyon cell | adult stage" FBgn0001223 Hsp22 Heat shock protein 22 http://flybase.net/reports/FBgn0001223.html "FBgn0044743, FBgn0052041, FBgn0061943, FBtr0076448, FBpp0076176, FBtr0076449, FBpp0076177, FBtr0076450, FBpp0076178, FBtr0076451, FBpp0076179" protein_coding_gene "0008340=determination of adult lifespan, 0006979=response to oxidative stress, 0042026=protein refolding, 0009408=response to heat" "EP(3)3247, heat-shock protein 22, DmHsp22, heat shock protein hsp22, Protein 22, hsp22, 22, small hsp locus 67B, CG32041, anon-WO0140519.138, heat shock protein 22, CG4460, HSP22, anon-WO0118547.50" "IPR031107=Small heat shock protein HSP20, IPR008978=HSP20-like chaperone, IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain" CG4460 16-Dec-15 2015_12 "ENSDARG00000041065(hspb1),ENSDARG00000058362(LOC100331249),ENSDARG00000052447(cryabb),ENSDARG00000058365(hspb8)" "WBGene00004798(sip-1),WBGene00002020(hsp-16.49),WBGene00002015(hsp-16.1),WBGene00002018(hsp-16.41),WBGene00002016(hsp-16.2),WBGene00008592(F08H9.4)" prepupal stage "cold stress response defective,viable,fertile,long lived,short lived,locomotor behavior defective,oxidative stress response defective,tetracycline conditional,heat stress response defective" FBgn0053878 His2B:CG33878 His2B:CG33878 http://flybase.net/reports/FBgn0053878.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33878 "IPR000558=Histone H2B, IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold" CG33878 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0053812 His3:CG33812 His3:CG33812 http://flybase.net/reports/FBgn0053812.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33812 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG33812 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0039371 CG4960 http://flybase.net/reports/FBgn0039371.html FBgn0061430 protein_coding_gene BcDNA:AT31258 IPR004345=TB2/DP1/HVA22-related protein CG4960 16-Dec-15 2015_12 "ENSDARG00000052661(reep5),ENSDARG00000038694(zgc:101744),ENSDARG00000042965(reep6)" YPR028W(YOP1) WBGene00022127(yop-1) "ENSXETG00000021513(TNeu028a23.1),ENSXETG00000003708(TGas053h05.1)" ENSMUSG00000005873(Reep5) ENSG00000129625(REEP5) viable DRSC27774 EK -1.026019985 -0.127231246 1.766484873 0.662442011 1.692223132 1.442477815 FBgn0015831 Rtnl2 Rtnl2 http://flybase.net/reports/FBgn0015831.html FBgn0046598 protein_coding_gene "unnamed, rtnl2, trop, tropomyosin-like, CG1279, Tml84D, Tropomyosin-like-84D, anon-WO0170980.134" IPR003388=Reticulon CG1279 16-Dec-15 2015_12 "ENSDARG00000058028(rtn3),ENSDARG00000044601(rtn4a),ENSDARG00000016088(rtn2a),ENSDARG00000057027(rtn2b)" "ENSXETG00000002694(rtn3),ENSXETG00000004521(rtn4),ENSXETG00000016983(RTN1),ENSXETG00000024454(RTN2)" viable FBgn0035669 CG6592 http://flybase.net/reports/FBgn0035669.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis "lincRNA.S4213, SP105" "IPR001254=Serine proteases, trypsin domain, IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001314=Peptidase S1A, chymotrypsin-type" CG6592 16-Dec-15 2015_12 "ENSDARG00000056744(ela2),ENSDARG00000056765(ela2l),ENSDARG00000007276(ela3l),ENSDARG00000043173(zgc:92745),ENSDARG00000017314(zgc:92041),ENSDARG00000043171(zgc:112302),ENSDARG00000043175(zgc:112368),ENSDARG00000043168(zgc:92511),ENSDARG00000053323(zgc:112285),ENSDARG00000030893(zgc:154142)" "ENSMUSG00000062478(Ctrc),ENSMUSG00000023433(Cela3b),ENSMUSG00000058579(Cela2a),ENSMUSG00000078520,ENSMUSG00000023031(Cela1),ENSMUSG00000031957(Ctrb1),ENSMUSG00000031896(Ctrl)" "ENSG00000162438(CTRC),ENSG00000142615(CELA2A),ENSG00000219073(CELA3B),ENSG00000215704(CELA2B),ENSG00000142789(CELA3A),ENSG00000139610(CELA1),ENSG00000168928(CTRB2),ENSG00000168925(CTRB1),ENSG00000141086(CTRL)" FBgn0037446 Zif Zinc-finger protein http://flybase.net/reports/FBgn0037446.html FBgn0062045 protein_coding_gene "0008270=zinc ion binding, 0003677=DNA binding" "0035167=larval lymph gland hemopoiesis, 0007405=neuroblast proliferation, 0045196=establishment or maintenance of neuroblast polarity" 0005634=nucleus "anon-WO0118547.391, CG10267, Zif" "IPR015880=Zinc finger, C2H2-like, IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG10267 16-Dec-15 2015_12 "ENSDARG00000071720,ENSDARG00000071723,ENSDARG00000071714(si:dkey-20i20.5),ENSDARG00000071712,ENSDARG00000071713,ENSDARG00000071719(si:dkey-20i20.2),ENSDARG00000071716,ENSDARG00000071846,ENSDARG00000071812,ENSDARG00000071811(si:dkey-4c15.6),ENSDARG00000071829,ENSDARG00000071838,ENSDARG00000071819,ENSDARG00000071791,ENSDARG00000071792,ENSDARG00000052346,ENSDARG00000021484,ENSDARG00000071767(LOC100150655),ENSDARG00000071815(LOC100150260),ENSDARG00000071580,ENSDARG00000040146,ENSDARG00000071833,ENSDARG00000044847(zgc:171599),ENSDARG00000022905,ENSDARG00000071820,ENSDARG00000071858,ENSDARG00000071725(zgc:174919),ENSDARG00000038478(LOC100150696)" "neuroanatomy defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,female sterile,female semi-sterile,recessive" "neuroblast,somatic clone,supernumerary" DRSC12514 I -0.690583247 -2.09509372 0.195435511 -0.741777976 0.992794517 -0.307770294 FBgn0032340 Ge-1 Ge-1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0032340.html protein_coding_gene 0005515=protein binding "0035195=gene silencing by miRNA, 0050832=defense response to fungus, 0045451=pole plasm oskar mRNA localization, 0033962=cytoplasmic mRNA processing body assembly" 0000932=cytoplasmic mRNA processing body "dGe-1, GE-1, EDC4, CG6181" "IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001680=WD40 repeat" CG6181 16-Dec-15 2015_12 ENSDARG00000062266(edc4) WBGene00021551(Y44E3A.6) ENSXETG00000005809(EDC4) ENSMUSG00000036270(Edc4) ENSG00000038358(EDC4) "lethal,recessive,immune response defective,dominant,partially lethal - majority die,visible,body color defective" "dorsal appendage,germline clone,embryonic/larval cuticle,denticle belt,mesothoracic tergum" FBgn0040273 Spt5 Spt5 http://flybase.net/reports/FBgn0040273.html FBgn0034445 protein_coding_gene 0046982=protein heterodimerization activity "0006351=transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint, 0032785=negative regulation of DNA-templated transcription, elongation, 0032786=positive regulation of DNA-templated transcription, elongation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007052=mitotic spindle organization, 0007549=dosage compensation, 0006368=transcription elongation from RNA polymerase II promoter" "0008023=transcription elongation factor complex, 0005634=nucleus, 0035101=FACT complex, 0000176=nuclear exosome (RNase complex), 0005700=polytene chromosome, 0032044=DSIF complex, 0005705=polytene chromosome interband, 0005703=polytene chromosome puff" "dSpt5, Dspt5, dDSIF, DSIF, SPT5, spt5, CG7626, Complementation group C" "IPR017071=Transcription elongation factor Spt5, IPR006645=NusG, N-terminal, IPR022581=Spt5 transcription elongation factor, N-terminal, IPR005100=Transcription elongation factor Spt5, NGN domain, IPR024945=Spt5 C-terminal domain, IPR008991=Translation protein SH3-like domain, IPR005824=KOW" CG7626 16-Dec-15 2015_12 ENSDARG00000042724(supt5h) YML010W(SPT5) WBGene00005015(spt-5) ENSXETG00000002888(SUPT5H) ENSMUSG00000003435(Supt5h) ENSG00000196235(SUPT5H) "non-enhancer of variegation,non-suppressor of variegation,lethal,recessive,viable,body color defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic segment,maternal effect,denticle belt,embryonic/first instar larval cuticle,mesothoracic tergum" DRSC07556 I -2.141694729 1.256176222 -0.491828722 0.468526252 0.041459882 1.049607709 FBgn0259243 Pka-R1 "Protein kinase, cAMP-dependent, regulatory subunit type 1" http://flybase.net/reports/FBgn0259243.html "FBgn0000275, FBgn0040635, FBgn0037029" protein_coding_gene "0030551=cyclic nucleotide binding, 0008603=cAMP-dependent protein kinase regulator activity" "2000253=positive regulation of feeding behavior, 0045471=response to ethanol, 0008355=olfactory learning, 0007274=neuromuscular synaptic transmission, 0007015=actin filament organization, 0019933=cAMP-mediated signaling, 0001932=regulation of protein phosphorylation, 0007591=molting cycle, chitin-based cuticle, 0008103=oocyte microtubule cytoskeleton polarization" 0005952=cAMP-dependent protein kinase complex "cAMP-dependent protein kinase, CG18677, Pka-RI, PKAr, PkaR, type I regulatory subunit of cAMP-dependent protein kinase, PKAR, dr[[1]], CG42341, CG12452, PKA, pkA, CG3263, regulatory subunit of PKA, regulatory subunit of protein kinase A, dPKA-RI, DRI, protein kinase A, PKA-RI, 18304, PKAi, PKa-R1, PKA-R1, CdkR, pKA, RI, pka-R1, cAMP-dependent protein kinase R1" "IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain, IPR012198=cAMP-dependent protein kinase regulatory subunit, IPR014710=RmlC-like jelly roll fold, IPR018488=Cyclic nucleotide-binding, conserved site, IPR003117=cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG42341 16-Dec-15 2015_12 "ENSDARG00000003541(LOC100329979),ENSDARG00000012094(prkar1ab)" WBGene00002190(kin-2) ENSXETG00000001377(Q5BL84_XENTR) "ENSMUSG00000025855(Prkar1b),ENSMUSG00000020612(Prkar1a)" "ENSG00000188191(PRKAR1B),ENSG00000108946(PRKAR1A)" " embryonic stage -- adult stage , adult stage " adult head

DRSC11674 IE -0.048523439 -3.68264299 -0.999875848 -3.004900401 -0.375247981 -0.428576086 FBgn0020545 kraken kraken http://flybase.net/reports/FBgn0020545.html protein_coding_gene 0017171=serine hydrolase activity "0007586=digestion, 0009636=response to toxic substance" "CG3943, Kraken" "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1" CG3943 16-Dec-15 2015_12 ENSDARG00000032340(serhl) "ENSXETG00000013413(),ENSXETG00000013415(Q66JC8_XENTR)" ENSMUSG00000058586(Serhl) "ENSG00000183569(SERHL2),ENSG00000172250" " embryonic stage | stage >=15 , larval stage | third instar , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 11-12 , embryonic stage | pre-blastoderm , embryonic stage | stage 13-15 , embryonic stage | stage 13 , embryonic stage | stage 11 " " gastric caecum

, ventral thoracic disc

, embryonic/larval midgut | anterior

, anterior midgut proper primordium

, posterior midgut proper primordium

, eye disc

, organism

, embryonic/larval posterior spiracle

, embryonic/larval hindgut

, embryonic/larval midgut

, embryonic/larval foregut

, embryonic/larval fat body

, embryonic/larval pharynx

" "viable,fertile" FBgn0024811 Crk Crk oncogene http://flybase.net/reports/FBgn0024811.html protein_coding_gene "0005070=SH3/SH2 adaptor activity, 0005515=protein binding" "0046330=positive regulation of JNK cascade, 0043087=regulation of GTPase activity, 0006911=phagocytosis, engulfment, 0032956=regulation of actin cytoskeleton organization, 0007520=myoblast fusion, 0046529=imaginal disc fusion, thorax closure, 0007165=signal transduction, 0007298=border follicle cell migration, 0048013=ephrin receptor signaling pathway" "Crk, dCRK, CRK, DCrk, dCrk, D-CRK, CG1587, Dcrk, D-Crk, crk" "IPR000980=SH2 domain, IPR011511=Variant SH3 domain, IPR001452=SH3 domain" CG1587 16-Dec-15 2015_12 "ENSDARG00000055635(crk),ENSDARG00000028699(crkl)" WBGene00000416(ced-2) "ENSXETG00000004258(CRKL),ENSXETG00000022904(crk)" "ENSMUSG00000017776(Crk),ENSMUSG00000006134(Crkl)" "ENSG00000099942(CRKL),ENSG00000167193(CRK)" " embryonic stage | stage >=13 , embryonic stage | stage 6,7 , embryonic stage | stage 8-12 , embryonic stage | stage 16 , embryonic stage -- adult stage , embryonic stage | stage 8 , embryonic stage | stage 13 " " ventral nerve cord

, mesoderm

, posterior embryonic/larval midgut

, embryonic procephalic segment

, anterior embryonic/larval midgut

, muscle fiber

, embryonic/larval visceral muscle

, cephalic furrow | vicinity of

, somatic mesoderm

, visceral mesoderm

" "lethal,recessive,viable,neuroanatomy defective" "thorax,border follicle cell,reticular neuropil associated glial cell,gamma Kenyon cell" FBgn0015929 dpa disc proliferation abnormal http://flybase.net/reports/FBgn0015929.html FBgn0004127 protein_coding_gene "0043138=3'-5' DNA helicase activity, 0003677=DNA binding, 0005524=ATP binding" "0042023=DNA endoreduplication, 0006260=DNA replication, 0006270=DNA replication initiation, 0007052=mitotic spindle organization" "0042555=MCM complex, 0005634=nucleus" "43Ca, DmeMCM4, mcm4, Dpa, l(2)43Ca, MCM4_DROME, DmMCM4, MCM4, DmMcm4, CG1616, Mcm4, Drosophila proliferation abnormal" "IPR027925=MCM N-terminal domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR008047=Mini-chromosome maintenance complex protein 4, IPR018525=Mini-chromosome maintenance, conserved site, IPR012340=Nucleic acid-binding, OB-fold, IPR004039=Rubredoxin-type fold, IPR003593=AAA+ ATPase domain, IPR001208=MCM domain, IPR031327=Mini-chromosome maintenance protein" CG1616 16-Dec-15 2015_12 ENSDARG00000040041(mcm4) YPR019W(MCM4) WBGene00003156(mcm-4) ENSXETG00000004854(mcm4) ENSMUSG00000022673(Mcm4) ENSG00000104738(MCM4) " embryonic stage | stage >=13 , larval stage | third instar , embryonic stage | stage >=12 , embryonic stage | stage 10-12 , embryonic stage | stage <=11 , embryonic stage | stage 16,17 , adult stage && oogenesis stage , adult stage | female && oogenesis stage " " embryonic brain

, embryonic/larval hindgut

, imaginal disc

, eye-antennal disc

, anterior embryonic/larval midgut

, Malpighian tubule

, embryonic central nervous system | presumptive

, epidermis

, gonad

, neuroblast

, oocyte

, peripheral nervous system

, optic lobe

, germline cell

, posterior embryonic/larval midgut

, nurse cell

" "some die during pupal stage,wild-type,lethal - all die before end of pupal stage,recessive,viable,visible" "mitotic cell cycle,mitotic metaphase,spindle,mitosis & nuclear chromosome,chromosome, centromeric region,imaginal disc,central nervous system,trichogen cell,mesothoracic tergum" FBgn0011260 Sema-2a Sema-2a http://flybase.net/reports/FBgn0011260.html FBgn0062466 protein_coding_gene 0005515=protein binding "0071678=olfactory bulb axon guidance, 0070983=dendrite guidance, 0007629=flight behavior, 0030534=adult behavior, 0007632=visual behavior, 0016201=synaptic target inhibition, 0007431=salivary gland development, 0007411=axon guidance, 0042756=drinking behavior, 0097374=sensory neuron axon guidance" "0005576=extracellular region, 0005829=cytosol, 0012505=endomembrane system" "D-Semaphorin II, BcDNA:LD09561, CT14922, D-semaII, semaphorin 2a, semaII, sema 2a, l(2)03021, semaphorin II, sema-II, sema-2a, Sema2a, D-Sema II, sema II, D-Sema2a, semiphorin, sema2a, D-Sema-II, Dsema-II, SemaII, dSema-II, Semaphorin II, semaphorin, CG4700, D-SemaII, 112/40" "IPR007110=Immunoglobulin-like domain, IPR027231=Semaphorin, IPR013783=Immunoglobulin-like fold, IPR016201=Plexin-like fold, IPR003599=Immunoglobulin subtype, IPR015943=WD40/YVTN repeat-like-containing domain, IPR001627=Sema domain" CG4700 16-Dec-15 2015_12 WBGene00003111(mab-20) "ENSXETG00000018720(SEMA6A),ENSXETG00000010843(SEMA4D),ENSXETG00000018391(SEMA6D),ENSXETG00000005837(SEMA6C),ENSXETG00000012967(SEMA4B),ENSXETG00000001251(SEMA4C),ENSXETG00000015209(SEMA4G),ENSXETG00000018164(SEMA4A)" " embryonic stage | stage 10 , embryonic stage | stage >=15 , embryonic stage | stage >=14 , embryonic stage " " epidermis | stripes

, central nervous system | restricted

, hypodermal muscle of metathorax | ventral

, gonad

, sense organ | anterior

, embryonic neuron

" "viable,fertile,neuroanatomy defective,lethal,recessive,flightless,behavior defective" "synapse,abdominal ventral longitudinal muscle 2 & neuromuscular junction,abdominal ventral longitudinal muscle 3 & neuromuscular junction,abdominal ventral longitudinal muscle 4 & neuromuscular junction,abdominal segment border muscle & neuromuscular junction,neuromuscular junction | ectopic,abdominal lateral oblique muscle 1 & neuromuscular junction,intersegmental nerve,transverse nerve,abdominal segmental nerve,imaginal disc,abdominal 1 VO2 motor neuron,abdominal 2 VO2 motor neuron,abdominal 1 VL3/4 motor neuron,abdominal 2 VL3/4 motor neuron,RP3 motor neuron,intersegmental nerve branch ISNb of A1-7" FBgn0040227 eIF-3p66 Eukaryotic initiation factor 3 p66 subunit http://flybase.net/reports/FBgn0040227.html "FBgn0026594, FBgn0039100" protein_coding_gene 0003743=translation initiation factor activity "0006446=regulation of translational initiation, 0006412=translation, 0006413=translational initiation" "0005829=cytosol, 0005634=nucleus, 0005852=eukaryotic translation initiation factor 3 complex" "BEST:GM10514, eiF3p66, 153314_at, GM10514, eIF3-S7, CG10161, eIF3d, eIF3p66, GM04979, eIF-3p66" IPR007783=Eukaryotic translation initiation factor 3 subunit D CG10161 16-Dec-15 2015_12 ENSDARG00000021257(eif3d) WBGene00001227(eif-3.D) ENSXETG00000027259(eif3s7) ENSMUSG00000016554(Eif3d) ENSG00000100353(EIF3D) "visible,wild-type,long lived" eye DRSC16938 EK -0.673970952 -1.183548318 1.512784687 -0.369327199 1.533031702 3.980798532 FBgn0026582 Hmg-2 High mobility group protein 2 http://flybase.net/reports/FBgn0026582.html FBgn0034594 protein_coding_gene 0016568=chromatin modification 0005634=nucleus "LD07122, CG9418, BEST:LD07122, High mobility group protein 1/2" IPR009071=High mobility group box domain CG9418 16-Dec-15 2015_12 "ENSDARG00000031198(hmg20a),ENSDARG00000042045(hmg20b)" "ENSXETG00000015269(hmg20a),ENSXETG00000022092(Q6P854_XENTR)" "ENSMUSG00000032329(Hmg20a),ENSMUSG00000020232(Hmg20b)" "ENSG00000064961(HMG20B),ENSG00000140382(HMG20A)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04554 I 0.210395311 -2.182004598 -0.365023532 -0.458682818 -0.935016866 0.241862931 FBgn0283469 Vps4 Vacuolar protein sorting 4 http://flybase.net/reports/FBgn0283469.html "FBgn0264354, FBgn0027605" protein_coding_gene "0016887=ATPase activity, 0005524=ATP binding" "0043162=ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, 0006909=phagocytosis, 0030036=actin cytoskeleton organization, 0045746=negative regulation of Notch signaling pathway, 0045463=R8 cell development, 0045470=R8 cell-mediated photoreceptor organization, 0000046=autophagic vacuole fusion, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0006886=intracellular protein transport, 0044130=negative regulation of growth of symbiont in host, 0045742=positive regulation of epidermal growth factor receptor signaling pathway" "1990621=Vps4-Vta1 complex, 0005768=endosome" "Dvps4, vacuolar protein sorting 4, BcDNA:GH02678, 3B1, bcDNA:GH02678, CG6842, DmBcDNA.GH02678, dvps4, vps4, Vps4B" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core, IPR007330=MIT, IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR015415=Vps4 oligomerisation, C-terminal" CG6842 16-Dec-15 2015_12 "ENSDARG00000069175(vps4b),ENSDARG00000070706" YPR173C(VPS4) WBGene00021334(vps-4) "ENSXETG00000017838(VPS4A),ENSXETG00000000638(vps4b)" "ENSMUSG00000009907(Vps4b),ENSMUSG00000031913(Vps4a)" "ENSG00000119541(VPS4B),ENSG00000132612(VPS4A)" DRSC19338 IEK -0.638358511 -2.86606776 0.120902631 -5.012199287 -2.682337979 -3.600187753 FBgn0015614 CanB2 Calcineurin B2 http://flybase.net/reports/FBgn0015614.html FBgn0033220 protein_coding_gene "0005509=calcium ion binding, 0005515=protein binding, 0008597=calcium-dependent protein serine/threonine phosphatase regulator activity, 0005516=calmodulin binding" "0016192=vesicle-mediated transport, 0007126=meiotic nuclear division, 0045214=sarcomere organization, 0030241=skeletal muscle myosin thick filament assembly, 0007269=neurotransmitter secretion, 0006470=protein dephosphorylation, 0030431=sleep" "0005955=calcineurin complex, 0008021=synaptic vesicle" "calcineurin B2, dCnB2, CG11217, canB2, Calcineurin suppressor, chromosome 2, group 1, CS2-1, dCNB2" "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG11217 16-Dec-15 2015_12 "ENSDARG00000069360,ENSDARG00000013013(ppp3r1a)" YKL190W(CNB1) WBGene00000554(cnb-1) ENSXETG00000017355(ppp3r1) ENSMUSG00000033953(Ppp3r1) ENSG00000115953 pupal stage--adult stage "flightless,partially lethal - majority die,meiotic cell cycle defective,germline clone,female sterile,lethal,recessive,sleep defective,viable,visible,hyperactive,smell perception defective" "indirect flight muscle,dorsal medial muscle,wing,indirect flight muscle | P-stage,dorsal medial muscle | P-stage,myofibril[-],sarcomere[-],trichogen cell" FBgn0037490 CG10053 http://flybase.net/reports/FBgn0037490.html "FBgn0046243, FBgn0046246" protein_coding_gene 0003676=nucleic acid binding "BEST:LD45537, BEST:LD41878" "IPR025239=Domain of unknown function DUF4187, IPR000467=G-patch domain" CG10053 16-Dec-15 2015_12 ENSDARG00000026892(zgc:92714) YLR271W() WBGene00011451(T04H1.5) ENSXETG00000018544(BC076886.1) ENSMUSG00000050668(Ccdc75) ENSG00000152133(CCDC75) viable FBgn0030699 CG8578 http://flybase.net/reports/FBgn0030699.html protein_coding_gene 0007527=adult somatic muscle development IPR019139=Leucine-rich repeat flightless-interacting protein CG8578 16-Dec-15 2015_12 "ENSDARG00000018186,ENSDARG00000010400(lrrfip2)" WBGene00018998(flap-1) ENSXETG00000004994(LRRFIP2) ENSMUSG00000032497(Lrrfip2) ENSG00000093167(LRRFIP2) viable "indirect flight muscle,myofibrilMef2.PR" FBgn0029911 CG14435 http://flybase.net/reports/FBgn0029911.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG14435 16-Dec-15 2015_12 ENSDARG00000020475(znrf1) WBGene00022115(Y71F9AL.10) ENSXETG00000022011(ZNRF2) ENSMUSG00000058446(Znrf2) ENSG00000180233(ZNRF2) "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053884 His2B:CG33884 His2B:CG33884 http://flybase.net/reports/FBgn0053884.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33884 "IPR000558=Histone H2B, IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3" CG33884 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0033465 Etf-QO Electron transfer flavoprotein-ubiquinone oxidoreductase http://flybase.net/reports/FBgn0033465.html protein_coding_gene 0004174=electron-transferring-flavoprotein dehydrogenase activity "0006119=oxidative phosphorylation, 0006635=fatty acid beta-oxidation" "0005875=microtubule associated complex, 0005739=mitochondrion, 0005811=lipid particle, 0005743=mitochondrial inner membrane" "electron transfer flavoprotein:ubiquinone oxidoreductase, ETF:QO, ETFD, electron transfer flavoprotein-ubiquinone oxidoreductase, Electron transfer flavoprotein-ubiquinone oxidoreductase, CG12140, ETFDH, CG 12140" IPR007859=Electron transfer flavoprotein-ubiquinone oxidoreductase CG12140 16-Dec-15 2015_12 ENSDARG00000038834(etfdh) YOR356W() WBGene00002855(let-721) ENSXETG00000019489(etfdh) ENSMUSG00000027809(Etfdh) ENSG00000171503(ETFDH) "increased cell death,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,viable" embryonic/larval cuticle FBgn0031214 CG11374 http://flybase.net/reports/FBgn0031214.html protein_coding_gene "0030246=carbohydrate binding, 0016936=galactoside binding, 0015143=urate transmembrane transporter activity" "IPR013320=Concanavalin A-like lectin/glucanase domain, IPR001079=Galectin, carbohydrate recognition domain" CG11374 16-Dec-15 2015_12 "ENSDARG00000069058(zgc:171951),ENSDARG00000054816,ENSDARG00000041060(zgc:92326),ENSDARG00000025903(lgals9l1)" "ENSXETG00000007928(),ENSXETG00000019079(lgals9),ENSXETG00000002843(lgals4)" "ENSMUSG00000001123(Lgals9),ENSMUSG00000053964(Lgals4),ENSMUSG00000057554(Lgals8)" "ENSG00000171747(LGALS4),ENSG00000170298(LGALS9B),ENSG00000171916(LGALS9C),ENSG00000168961(LGALS9),ENSG00000116977(LGALS8)" viable FBgn0032949 Lamp1 Lamp1 http://flybase.net/reports/FBgn0032949.html protein_coding_gene 0048812=neuron projection morphogenesis "0005764=lysosome, 0016020=membrane" "lysosome-associated membrane protein, LAMP1, dLAMP, Lamp, lysosomal-associated membrane protein 1, lamp1, Lamp-1, dLamp, LAMP, CG3305" IPR002000=Lysosome-associated membrane glycoprotein CG3305 16-Dec-15 2015_12 "ENSDARG00000014914(lamp2),ENSDARG00000015129,ENSDARG00000055504(wu:fb66f03)" "ENSXETG00000001958(LAMP1),ENSXETG00000004476(LAMP2)" "ENSMUSG00000031447(Lamp1),ENSMUSG00000016534(Lamp2)" "ENSG00000185896(LAMP1),ENSG00000005893(LAMP2)" "neuroanatomy defective,conditional,viable,fertile,decreased cell death,recessive,somatic clone" "dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional" FBgn0015351 CG14906 http://flybase.net/reports/FBgn0015351.html protein_coding_gene "0008168=methyltransferase activity, 0003676=nucleic acid binding" "0006139=nucleobase-containing compound metabolic process, 0032259=methylation" "anon-89Eb, open reading frame 2, ORF2" "IPR002052=DNA methylase, N-6 adenine-specific, conserved site, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR007757=MT-A70-like" CG14906 16-Dec-15 2015_12 WBGene00015939(C18A3.1) ENSXETG00000001604(METTL4) ENSMUSG00000055660(Mettl4) ENSG00000101574(METTL4) "viable,fertile" DRSC26716 K 1.343712903 -0.579608899 0.453300475 0.340057196 1.523059117 -0.356035364 FBgn0032131 CG3841 http://flybase.net/reports/FBgn0032131.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "IPR002018=Carboxylesterase, type B, IPR019826=Carboxylesterase type B, active site, IPR029058=Alpha/Beta hydrolase fold" CG3841 16-Dec-15 2015_12 "ENSDARG00000041595(ces3),ENSDARG00000041569(ces2),ENSDARG00000070915" "ENSMUSG00000031877(2210023G05Rik),ENSMUSG00000061825(Ces2),ENSMUSG00000050097(BC015286),ENSMUSG00000031884(Gm9756),ENSMUSG00000031886(Ces5),ENSMUSG00000055730(Ces6),ENSMUSG00000062826(2310038E17Rik),ENSMUSG00000056973(Ces3),ENSMUSG00000061959(Es22),ENSMUSG00000057074(Ces1),ENSMUSG00000057400(Es1),ENSMUSG00000078964(Gm5158),ENSMUSG00000031725(AU018778),ENSMUSG00000071047(Gm4976),ENSMUSG00000074156(2310039D24Rik),ENSMUSG00000069922(Es31),ENSMUSG00000062181(Gm4738),ENSMUSG00000060560(Ces8),ENSMUSG00000058019(Ces7)" viable FBgn0035082 CG2811 http://flybase.net/reports/FBgn0035082.html FBgn0047065 protein_coding_gene BcDNA:RE67445 "IPR013024=Butirosin biosynthesis, BtrG-like, IPR009288=Gamma-glutamylcyclotransferase, AIG2-like" CG2811 16-Dec-15 2015_12 "ENSDARG00000070579(zgc:162208),ENSDARG00000038248(zgc:92115),ENSDARG00000070581(zgc:154024)" WBGene00023489(F42A10.9) ENSXETG00000024582(A2LD1) ENSMUSG00000041625(A2ld1) ENSG00000134864(A2LD1) viable DRSC04318 I 3.229163886 -0.62089587 -0.04810969 0.427897583 0.427894251 1.072220096 FBgn0033502 CG12910 http://flybase.net/reports/FBgn0033502.html protein_coding_gene IPR008166=Glycosyltransferase family 92 CG12910 16-Dec-15 2015_12 ENSDARG00000054363 "WBGene00015311(C01G5.9),WBGene00015870(C17A2.2),WBGene00015762(C14C6.8),WBGene00007424(C08B6.3),WBGene00022758(ZK488.6),WBGene00017019(D1014.6),WBGene00017020(D1014.7),WBGene00015761(C14C6.7),WBGene00020247(T05B11.4),WBGene00022757(ZK488.5),WBGene00019452(K06H6.4),WBGene00018498(F46F5.7),WBGene00011784(T15D6.10),WBGene00016282(C31B8.7),WBGene00020280(T06A1.5)" viable FBgn0034389 Mctp Multiple C2 domain and transmembrane region protein http://flybase.net/reports/FBgn0034389.html "FBan0033146, FBgn0053146, FBgn0053148" protein_coding_gene 0005509=calcium ion binding 0016021=integral component of membrane "CG15078, CG33148, DmMCTP, CG33146" "IPR013583=Phosphoribosyltransferase C-terminal, IPR000008=C2 domain" CG15078 16-Dec-15 2015_12 WBGene00017063(D2092.1) "ENSXETG00000013380(BC089707.1),ENSXETG00000024140(MCTP2)" "ENSMUSG00000021596(Mctp1),ENSMUSG00000032776(Mctp2)" "ENSG00000175471(MCTP1),ENSG00000140563(MCTP2)" "viable,fertile,lethal" FBgn0003008 or orange http://flybase.net/reports/FBgn0003008.html FBgn0034944 protein_coding_gene 0008565=protein transporter activity "0048072=compound eye pigmentation, 0006726=eye pigment biosynthetic process, 0006901=vesicle coating, 0016183=synaptic vesicle coating, 0046907=intracellular transport, 0016192=vesicle-mediated transport, 0006886=intracellular protein transport, 0007040=lysosome organization, 0007269=neurotransmitter secretion, 0006727=ommochrome biosynthetic process" "0008021=synaptic vesicle, 0030123=AP-3 adaptor complex, 0030135=coated vesicle" "Adaptor Protein complex 3, sigma subunit, sigma3, AP-3sigma, aps3, CG3029, cg3029, Or, Orange" "IPR027155=AP-3 complex subunit sigma, IPR011012=Longin-like domain, IPR000804=Clathrin adaptor complex, small chain, IPR016635=Adaptor protein complex, sigma subunit, IPR022775=AP complex, mu/sigma subunit" CG3029 16-Dec-15 2015_12 ENSDARG00000039882(LOC100334392) YJL024C(APS3) WBGene00000165(aps-3) "ENSXETG00000012972(ap3s2),ENSXETG00000027374(ap3s1)" "ENSMUSG00000063801(Ap3s2),ENSMUSG00000024480(Ap3s1)" "ENSG00000157823(AP3S2),ENSG00000177879(AP3S1)" "viable,fertile,eye color defective,visible,recessive,somatic clone,locomotor behavior defective" "photoreceptor cell pigment granule,pigment cell,somatic clone,mesothoracic tergum" FBgn0061469 Ube3a Ubiquitin protein ligase E3A http://flybase.net/reports/FBgn0061469.html FBgn0036148 protein_coding_gene "0004842=ubiquitin-protein transferase activity, 0061630=ubiquitin protein ligase activity" "0007616=long-term memory, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process, 0007623=circadian rhythm, 0048813=dendrite morphogenesis, 0000209=protein polyubiquitination, 0040011=locomotion, 0048935=peripheral nervous system neuron development, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process" "0005737=cytoplasm, 0005634=nucleus, 0005938=cell cortex" "dube3A, Dube3a, Drosophila Angelman syndrome, CG6190, AS, As, das, NM_140195.2, Angelman syndrome, dube3a, UBE3A, dUBE3A, ube3a" "IPR017134=Ubiquitin-protein ligase E6-AP, IPR000569=HECT domain" CG6190 16-Dec-15 2015_12 ENSDARG00000055737(ube3a) YJR036C(HUL4) ENSXETG00000024326(ube3a) ENSMUSG00000025326(Ube3a) ENSG00000114062(UBE3A) "locomotor behavior defective,viable,neuroanatomy defective,lethal,male limited,recessive,fertile,chemosensitive behavior defective,gravitaxis defective,memory defective,locomotor rhythm defective,wild-type,size defective" "wing margin,eye,ommatidium,photoreceptor cell,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaF,dorsal multidendritic neuron ddaC,retina,wing,interommatidial bristle" FBgn0025469 slv saliva http://flybase.net/reports/FBgn0025469.html FBgn0025735 protein_coding_gene 0051119=sugar transmembrane transporter activity "0006310=DNA recombination, 0007431=salivary gland development" 0016021=integral component of membrane "Saliva, CG8717" IPR018180=Sugar transporter SWEET1 CG8717 16-Dec-15 2015_12 ENSDARG00000015158(rag1ap1) WBGene00012647(Y39A1A.8) ENSXETG00000019427(Q5EAL3_XENTR) ENSMUSG00000027953(Rag1ap1) ENSG00000169241(SLC50A1) " embryonic stage -- adult stage , embryonic stage | stage >=11 " salivary gland body primordium

"neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell" DRSC07685 K -0.645730842 0.336846528 0.17246838 0.239703586 -1.002599646 -1.603142114 FBgn0024227 aurB aurora B http://flybase.net/reports/FBgn0024227.html protein_coding_gene "0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0004712=protein serine/threonine/tyrosine kinase activity" "0043988=histone H3-S28 phosphorylation, 0016572=histone phosphorylation, 0032467=positive regulation of cytokinesis, 0008608=attachment of spindle microtubules to kinetochore, 0000281=mitotic cytokinesis, 0031577=spindle checkpoint, 0006325=chromatin organization, 0006468=protein phosphorylation, 0048132=female germ-line stem cell asymmetric division, 0007052=mitotic spindle organization, 0090307=mitotic spindle assembly, 0000070=mitotic sister chromatid segregation, 0007076=mitotic chromosome condensation, 0022008=neurogenesis, 0000920=cell separation after cytokinesis" "0032133=chromosome passenger complex, 0000780=condensed nuclear chromosome, centromeric region, 0005819=spindle, 0000775=chromosome, centromeric region, 0000776=kinetochore, 1990385=meiotic spindle midzone, 0030496=midbody, 0051233=spindle midzone" "Aurora B, ial, IAL1, IAL, aurB, IplI-aurora-like kinase, ABK, Ial, AuroraB, Aurora-B, AurB, aurora B, AURORA-like, Aur B, Aurora, DmAIRK2, CG6620, DmAuroraB, dAurora B, auroraB, aurora B kinase, DmAurB, aurora-B, Aurora B kinase, ial/AurB" "IPR028772=Aurora kinase B, IPR030616=Aurora kinase, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG6620 16-Dec-15 2015_12 WBGene00000099(air-2) " embryonic stage | syncytial blastoderm , embryonic stage | stage 11-13 , embryonic stage | stage >=7 , embryonic stage | stage >=14 , adult stage && oogenesis stage | stage S9-10 , adult stage && oogenesis stage | stage >=S9 , embryonic stage -- adult stage , adult stage && oogenesis stage " " ventral nerve cord | segmentally repeated

,

segmentally repeated , ventral nerve cord | restricted

, nurse cell

, oocyte

" adult stage && oogenesis stage ovariole

"mitotic cell cycle defective,cytokinesis defective,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,increased cell size" "mitotic cell cycle, with aurBcGa,mitosis & nuclear chromosome, with aurBcGa,mitotic anaphase, with aurBcGa,mitotic cell cycle & chromosome, pericentric region, with aurBcGa,mitotic cell cycle & spindle, with aurBcGa,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,mitotic cell cycle,mitotic prometaphase & nuclear chromosome,spindle,mitotic cell cycle, with aurBa.cGa,mitosis & nuclear chromosome, with aurBa.cGa,mitotic anaphase, with aurBa.cGa,mitotic cell cycle & chromosome, pericentric region, with aurBa.cGa,mitotic cell cycle & spindle, with aurBa.cGa,nucleus" FBgn0015229 glec gliolectin http://flybase.net/reports/FBgn0015229.html protein_coding_gene 0030246=carbohydrate binding "0007155=cell adhesion, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0007399=nervous system development" "0016021=integral component of membrane, 0005654=nucleoplasm" "CG6575, Gliolectin" CG6575 16-Dec-15 2015_12 embryonic stage | stage 11-15 ectoderm

segmentally repeated embryonic stage | stage 13-15 midline glial cell

"partially lethal - majority die,visible,lethal,recessive,viable" "scutellar bristle,trichogen cell,macrochaeta,germline cell,male,ventral nerve cord commissure,pCC neuron" FBgn0267384 Ubc7 Ubiquitin conjugating enzyme 7 http://flybase.net/reports/FBgn0267384.html "FBgn0015374, FBgn0030760, FBgn0013351" protein_coding_gene 0004842=ubiquitin-protein transferase activity "0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0000209=protein polyubiquitination" "Crl, Ubc47D, Ubiquitin-conjugating-enzyme-47D, courtless, crl, col, UBC7, CG4443" "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG4443 16-Dec-15 2015_12 ENSDARG00000025404(zgc:112077) YMR022W(UBC7) WBGene00006709(ubc-14) ENSXETG00000018628(ube2g2) ENSMUSG00000009293(Ube2g2) ENSG00000184787(UBE2G2) " embryonic stage -- adult stage , adult stage | male , embryonic stage | stage 10 , embryonic stage | stage 15 , embryonic stage | stage 6 , embryonic stage | stage 4 " " embryonic neuroblast

, embryonic central nervous system

, cephalic furrow

, stomodeal invagination

, mesoderm

" " embryonic stage | stage 7-8 , embryonic stage | stage 13-17 , embryonic stage | blastoderm " " endoderm

, embryonic central nervous system

, mesoderm

" FBgn0265052 St3 Sulfotransferase 3 http://flybase.net/reports/FBgn0265052.html "FBgn0034888, FBgn0034889" protein_coding_gene 0008146=sulfotransferase activity "0042742=defense response to bacterium, 0006805=xenobiotic metabolic process, 0051923=sulfation" 0005829=cytosol "st3, dmST3, CG44167, CG5431, CG11293" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR000863=Sulfotransferase domain" CG44167 16-Dec-15 2015_12 "ENSDARG00000053331(sult2st2),ENSDARG00000033170(sult2st1),ENSDARG00000028367(sult2st3),ENSDARG00000007769(zgc:153723),ENSDARG00000042919,ENSDARG00000040781(zgc:113317),ENSDARG00000042920(si:dkey-236e20.2),ENSDARG00000042923(sult3st2),ENSDARG00000009885(sult3st1),ENSDARG00000071495" "ENSXETG00000012821(BC061263.1),ENSXETG00000006064(TTpA004g18.1),ENSXETG00000019804(BC088870.1),ENSXETG00000010085(SULT2A1),ENSXETG00000014075(BC088888.1)" "ENSMUSG00000069668(Sult3a1),ENSMUSG00000003271(Sult2b1),ENSMUSG00000029273(Sult1d1),ENSMUSG00000023943(Sult1c1),ENSMUSG00000079135,ENSMUSG00000074375(Sult2a3),ENSMUSG00000029269(Sult1b1),ENSMUSG00000023122(Sult1c2),ENSMUSG00000078799,ENSMUSG00000074377(Sult2a4),ENSMUSG00000078798(Sult2a1),ENSMUSG00000029272(Sult1e1),ENSMUSG00000070810(Sult2a6)" "ENSG00000173597(SULT1B1),ENSG00000198075(SULT1C4),ENSG00000197165(SULT1A2),ENSG00000198203(SULT1C2),ENSG00000196502(SULT1A1),ENSG00000213599(SULT1A3),ENSG00000213648(SULT1A4),ENSG00000196228(SULT1C3),ENSG00000088002(SULT2B1),ENSG00000105398(SULT2A1)" FBgn0259697 nvd neverland http://flybase.net/reports/FBgn0259697.html "FBgn0058050, FBgn0086256" protein_coding_gene "0016491=oxidoreductase activity, 0051537=2 iron, 2 sulfur cluster binding" "0055114=oxidation-reduction process, 0045456=ecdysteroid biosynthetic process, 0002168=instar larval development, 0007552=metamorphosis, 0035264=multicellular organism growth" "CG40050, lethal 6, nvd-Dm, Neverland" IPR017941=Rieske [2Fe-2S] iron-sulphur domain CG40050 16-Dec-15 2015_12 ENSDARG00000034048(zgc:92275) WBGene00007536(daf-36) ENSXETG00000022934() FBgn0051611 His4:CG31611 His4:CG31611 http://flybase.net/reports/FBgn0051611.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" "0006334=nucleosome assembly, 0051276=chromosome organization" "0005634=nucleus, 0000786=nucleosome" CG31611 "IPR001951=Histone H4, IPR009072=Histone-fold, IPR019809=Histone H4, conserved site" CG31611 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" "viable,fertile" DRSC21268 IE -3.179513886 -3.964253834 -1.486507778 -5.104496797 -0.404127919 0.984476879 FBgn0024733 RpL10 Ribosomal protein L10 http://flybase.net/reports/FBgn0024733.html "FBan0017521, FBgn0026279, FBgn0064923" protein_coding_gene 0003735=structural constituent of ribosome "0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0006412=translation, 0051297=centrosome organization, 0007052=mitotic spindle organization" "0005737=cytoplasm, 0022625=cytosolic large ribosomal subunit, 0005840=ribosome, 0043025=neuronal cell body" "Rp L10, Ribosomal protein L10, L10, qm, RpL10, Ribosome RL10, Qm, DQM, BcDNA:LD24589, anon-EST:Posey179, 60S ribosomal protein L10, CG17521" "IPR016180=Ribosomal protein L10e/L16, IPR001197=Ribosomal protein L10e, IPR018255=Ribosomal protein L10e, conserved site" CG17521 16-Dec-15 2015_12 ENSDARG00000025581(rpl10) YLR075W(RPL10) WBGene00004421(rpl-10) ENSXETG00000010878(rpl10) "ENSMUSG00000008682(Rpl10),ENSMUSG00000060499(Rpl10l)" "ENSG00000178464,ENSG00000147403(RPL10),ENSG00000165496(RPL10L)" lethal DRSC11947 IEK -1.960887705 -2.572967388 -0.703076538 -4.272006674 3.099004985 3.442780039 FBgn0037955 CG6950 http://flybase.net/reports/FBgn0037955.html protein_coding_gene "0030170=pyridoxal phosphate binding, 0016212=kynurenine-oxoglutarate transaminase activity" 0009058=biosynthetic process "IPR015424=Pyridoxal phosphate-dependent transferase, IPR004839=Aminotransferase, class I/classII, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2" CG6950 16-Dec-15 2015_12 "ENSDARG00000013423(LOC100332215),ENSDARG00000043280,ENSDARG00000023645(ccbl1)" YJL060W(BNA3) "WBGene00010984(nkat-3),WBGene00009232(nkat-1)" "ENSXETG00000006090(kat3),ENSXETG00000012909(ccbl1)" ENSMUSG00000040213(Ccbl2) ENSG00000137944(CCBL2) "viable,fertile" FBgn0015040 Cyp9c1 Cytochrome P450-9c1 http://flybase.net/reports/FBgn0015040.html protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0016020=membrane" "P-450, CG3616, CYP9C1, P450, 9c1" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG3616 16-Dec-15 2015_12 ENSDARG00000045627(cyp3a65) YHR007C(ERG11) "WBGene00008810(cyp-13A12),WBGene00008809(cyp-13A11),WBGene00014254(cyp-13A10),WBGene00011677(cyp-13A1),WBGene00011674(cyp-13A8),WBGene00010606(cyp-13B2),WBGene00008519(cyp-13B1)" "ENSXETG00000011756(),ENSXETG00000025090(cyp3a7),ENSXETG00000022606(),ENSXETG00000005360()" "ENSMUSG00000056035(Cyp3a11),ENSMUSG00000075551(Cyp3a41a),ENSMUSG00000075552(Cyp3a41b),ENSMUSG00000054417(Cyp3a44),ENSMUSG00000038656(Cyp3a16),ENSMUSG00000029727(Cyp3a13),ENSMUSG00000029630(Cyp3a25),ENSMUSG00000070419(Cyp3a57),ENSMUSG00000061292(Cyp3a59)" "ENSG00000160868(CYP3A4),ENSG00000160870(CYP3A7),ENSG00000106258(CYP3A5),ENSG00000021461(CYP3A43),ENSG00000059377(TBXAS1)" FBgn0034624 CG17974 http://flybase.net/reports/FBgn0034624.html protein_coding_gene 0005576=extracellular region "IPR001283=Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044=CAP domain" CG17974 16-Dec-15 2015_12 "ENSDARG00000030650(si:dkey-24l7.3),ENSDARG00000045378(pi15a),ENSDARG00000061292(LOC556658),ENSDARG00000046021,ENSDARG00000045224" "WBGene00008030(scl-8),WBGene00015246(scl-23),WBGene00008029(scl-7),WBGene00008027(scl-5),WBGene00009895(scl-2),WBGene00009896(scl-3),WBGene00008625(scl-14),WBGene00017183(scl-15),WBGene00009892(scl-11),WBGene00004742(scl-1),WBGene00019178(scl-12),WBGene00019179(scl-13),WBGene00008028(scl-6),WBGene00009891(scl-10),WBGene00021780(scl-17),WBGene00013972(scl-20),WBGene00011724(scl-18),WBGene00009890(scl-9),WBGene00013971(scl-19),WBGene00011462(scl-22),WBGene00012816(scl-21)" ENSXETG00000001774(R3HDML) "ENSMUSG00000067780(Pi15),ENSMUSG00000078949(R3hdml),ENSMUSG00000020213(Glipr1l1),ENSMUSG00000056888(Glipr1),ENSMUSG00000020214(Glipr1l2)" "ENSG00000137558(PI15),ENSG00000101074(R3HDML),ENSG00000139278(GLIPR1),ENSG00000173401(GLIPR1L1),ENSG00000096006(CRISP3)" viable FBgn0039045 CG17119 http://flybase.net/reports/FBgn0039045.html protein_coding_gene "0015184=L-cystine transmembrane transporter activity, 0015171=amino acid transmembrane transporter activity" "0015811=L-cystine transport, 0003333=amino acid transmembrane transport" 0005765=lysosomal membrane CTNS "IPR005282=Lysosomal cystine transporter, IPR006603=PQ-loop repeat, IPR010916=TonB box, conserved site" CG17119 16-Dec-15 2015_12 ENSDARG00000008890(ctns) YCR075C(ERS1) WBGene00008052(ctns-1) ENSXETG00000005795(CTNS) ENSMUSG00000005949(Ctns) ENSG00000040531(CTNS) FBgn0024804 Dbp80 Dead box protein 80 http://flybase.net/reports/FBgn0024804.html "FBgn0020298, FBgn0024749, FBgn0042216, FBgn0047105, FBan0017023" protein_coding_gene "0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0003676=nucleic acid binding" 0044614=nuclear pore cytoplasmic filaments "CG17023, Hel80, mdcds_36124, Hel40, hel-40, unnamed, Helicase 40, DmDbp80, DBP80, HEL80, Helicase 80, BcDNA:RE44177" "IPR011545=DEAD/DEAH box helicase domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal" CG17023 16-Dec-15 2015_12 "ENSDARG00000005699(ddx19),ENSDARG00000044325(zgc:193690)" YOR046C(DBP5) ENSXETG00000028097(ddx19) "ENSMUSG00000015023(Ddx19a),ENSMUSG00000033658(Ddx19b),ENSMUSG00000032101(Ddx25)" "ENSG00000168872(DDX19A),ENSG00000157349(DDX19B),ENSG00000109832(DDX25)" FBgn0037683 CG18473 http://flybase.net/reports/FBgn0037683.html FBgn0037682 protein_coding_gene "0016787=hydrolase activity, 0008270=zinc ion binding, 0004063=aryldialkylphosphatase activity" 0009056=catabolic process CG8125 "IPR001559=Phosphotriesterase, IPR017947=Aryldialkylphosphatase, zinc-binding site" CG18473 16-Dec-15 2015_12 ENSDARG00000063375(pter) ENSXETG00000007448(PTER) ENSMUSG00000026730(Pter) ENSG00000165983(PTER) viable FBgn0031069 Pmp70 http://flybase.net/reports/FBgn0031069.html protein_coding_gene "0005524=ATP binding, 0005215=transporter activity, 0042626=ATPase activity, coupled to transmembrane movement of substances" "0055085=transmembrane transport, 0007031=peroxisome organization" "0043190=ATP-binding cassette (ABC) transporter complex, 0005778=peroxisomal membrane, 0005779=integral component of peroxisomal membrane" "CG12703, i17, PMP70" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003593=AAA+ ATPase domain, IPR011527=ABC transporter type 1, transmembrane domain, IPR003439=ABC transporter-like, IPR031241=ATP-binding cassette sub-family D member 3" CG12703 16-Dec-15 2015_12 "ENSDARG00000015167(abcd3a),ENSDARG00000002947(abcd3b)" YPL147W(PXA1) "WBGene00004059(pmp-2),WBGene00004058(pmp-1)" ENSXETG00000008218(ABCD3) ENSMUSG00000028127(Abcd3) ENSG00000117528(ABCD3) "viable,visible" trichogen cell FBgn0027070 CG17322 http://flybase.net/reports/FBgn0027070.html FBgn0032714 protein_coding_gene "0008194=UDP-glycosyltransferase activity, 0016758=transferase activity, transferring hexosyl groups" "0006805=xenobiotic metabolic process, 0006011=UDP-glucose metabolic process" 0005783=endoplasmic reticulum "BEST:LD25345, LD25345" IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG17322 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSXETG00000017935(BC075289.1),ENSXETG00000004890()" "ENSMUSG00000035780(Ugt2a3),ENSMUSG00000032854(Ugt8a),ENSMUSG00000035836(Ugt2b1),ENSMUSG00000029260(Ugt2b34),ENSMUSG00000029268(Ugt2a2),ENSMUSG00000070704(Ugt2b36),ENSMUSG00000035811(Ugt2b35),ENSMUSG00000054630(Ugt2b5),ENSMUSG00000061906(Ugt2b38),ENSMUSG00000057425(Ugt2b37),ENSMUSG00000054545(Ugt1a1)" viable FBgn0015324 Vha26 Vacuolar H+-ATPase 26kD subunit http://flybase.net/reports/FBgn0015324.html FBgn0024707 protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism" "0015992=proton transport, 0015991=ATP hydrolysis coupled proton transport" "0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0005886=plasma membrane, 0033181=plasma membrane proton-transporting V-type ATPase complex" "vha26, E subunit, Vacuolar H[+]-ATPase 26 kD E subunit, Vacuolar H+ATPase subunit E, ATP6V1E1, CG1088, BcDNA.GH03683, vATPase, Vacuolar H[+]-ATPase 26kD E subunit, VhaE, vacuolar ATP synthase subunit E, unnamed, BcDNA:GH03683, anon-83Bb, chr3R:1419698..1419836" "IPR002842=ATPase, V1/A1 complex, subunit E" CG1088 16-Dec-15 2015_12 "ENSDARG00000030694(atp6v1e1),ENSDARG00000014085(zgc:101757)" YOR332W(VMA4) WBGene00006917(vha-8) ENSXETG00000000869(Q6P8D7_XENTR) "ENSMUSG00000019210(Atp6v1e1),ENSMUSG00000053375(Atp6v1e2)" "ENSG00000131100(ATP6V1E1),ENSG00000171142" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" Malpighian tubule FBgn0263930 dally division abnormally delayed http://flybase.net/reports/FBgn0263930.html "FBgn0011577, FBgn0010889, FBgn0014962, FBgn0002464" protein_coding_gene "0005515=protein binding, 0043395=heparan sulfate proteoglycan binding" "0008101=decapentaplegic signaling pathway, 0008315=meiotic G2/MI transition, 0008052=sensory organ boundary specification, 0008045=motor neuron axon guidance, 0007472=wing disc morphogenesis, 0048749=compound eye development, 0045570=regulation of imaginal disc growth, 0016055=Wnt signaling pathway, 0007179=transforming growth factor beta receptor signaling pathway, 0048813=dendrite morphogenesis, 0008407=chaeta morphogenesis, 0008586=imaginal disc-derived wing vein morphogenesis, 0048190=wing disc dorsal/ventral pattern formation, 0022416=chaeta development, 0048132=female germ-line stem cell asymmetric division, 0040014=regulation of multicellular organism growth, 0030513=positive regulation of BMP signaling pathway, 0030510=regulation of BMP signaling pathway, 0007476=imaginal disc-derived wing morphogenesis, 0007399=nervous system development, 0030718=germ-line stem cell maintenance, 2001261=negative regulation of semaphorin-plexin signaling pathway, 0007409=axonogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0035220=wing disc development, 0051726=regulation of cell cycle" "0005578=proteinaceous extracellular matrix, 0016020=membrane, 0019897=extrinsic component of plasma membrane, 0098595=perivitelline space, 0009986=cell surface, 0005576=extracellular region" "Dally, gem, lethal (3) SG18, l(3)SG18, genitalia missing, l(3)06464, dally, Division abnormally delayed, CG4974, clone 1.63, anon-EST:Liang-1.63, CT15952" "IPR031187=Division abnormally delayed protein, IPR001863=Glypican" CG4974 16-Dec-15 2015_12 "ENSDARG00000015472(gpc4),ENSDARG00000019341(zgc:122977),ENSDARG00000012153" "ENSMUSG00000022112(Gpc5),ENSMUSG00000055653(Gpc3)" "ENSG00000179399(GPC5),ENSG00000147257(GPC3)" " larval stage | third instar , embryonic stage | stage 8 , embryonic stage , embryonic stage | early " " larval inner optic anlage

, eye-antennal disc

,

segment polarity , ventral thoracic disc

, dorsal mesothoracic disc

,

ubiquitous , lamina anlage

, ectoderm | restricted

" FBgn0039407 CG14544 http://flybase.net/reports/FBgn0039407.html protein_coding_gene 0016429=tRNA (adenine-N1-)-methyltransferase activity "0030488=tRNA methylation, 0046331=lateral inhibition" 0031515=tRNA (m1A) methyltransferase complex "IPR014816=tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase" CG14544 16-Dec-15 2015_12 ENSDARG00000008480(trmt61a) YJL125C(GCD14) WBGene00012192(W02A11.1) ENSXETG00000026907(TGas076l13.1) ENSMUSG00000060950(Trmt61a) ENSG00000166166(TRMT61A) "lethal,viable,visible" "embryonic/larval brain,chaeta,trichogen cell" FBgn0035231 Cct2 CTP:phosphocholine cytidylyltransferase 2 http://flybase.net/reports/FBgn0035231.html protein_coding_gene 0004105=choline-phosphate cytidylyltransferase activity 0009058=biosynthetic process 0005737=cytoplasm "CT1187, cct2, CG18330, CCT2" "IPR004821=Cytidyltransferase-like domain, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold" CG18330 16-Dec-15 2015_12 "ENSDARG00000011233(pcyt1aa),ENSDARG00000004492(pcyt1ab),ENSDARG00000058162(pcyt1ba),ENSDARG00000044456" WBGene00017241(F08C6.2) "ENSXETG00000003079(PCYT1A),ENSXETG00000021820(PCYT1B)" "ENSMUSG00000005615(Pcyt1a),ENSMUSG00000035246(Pcyt1b)" "ENSG00000161217(PCYT1A),ENSG00000102230(PCYT1B)" FBgn0264815 Pde1c http://flybase.net/reports/FBgn0264815.html "FBgn0032383, FBgn0032384, FBgn0032380, FBgn0051758, FBgn0259225, FBgn0032379, FBgn0051757, FBgn0264749" protein_coding_gene "0004114=3',5'-cyclic-nucleotide phosphodiesterase activity, 0004117=calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, 0004115=3',5'-cyclic-AMP phosphodiesterase activity, 0004867=serine-type endopeptidase inhibitor activity, 0048101=calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity, 0005516=calmodulin binding, 0047555=3',5'-cyclic-GMP phosphodiesterase activity" "0009187=cyclic nucleotide metabolic process, 0060179=male mating behavior, 0046058=cAMP metabolic process, 0030162=regulation of proteolysis, 0007165=signal transduction, 0046068=cGMP metabolic process, 0032504=multicellular organism reproduction" 0005615=extracellular space "CG42325, mdcds_1440, CG14940, PDE1C, CG31758, PDE1c, CG14944, Phosphodiesterase 1c, CG44007, CG14943, CG14942, CG31757" "IPR023088=3'5'-cyclic nucleotide phosphodiesterase, IPR003607=HD/PDEase domain, IPR013706=3'5'-cyclic nucleotide phosphodiesterase N-terminal, IPR023174=3'5'-cyclic nucleotide phosphodiesterase, conserved site, IPR002073=3'5'-cyclic nucleotide phosphodiesterase, catalytic domain" CG44007 16-Dec-15 2015_12 "ENSDARG00000067683,ENSDARG00000060875,ENSDARG00000012490" WBGene00011433(pde-1) ENSXETG00000023430(PDE1C) "ENSMUSG00000004347(Pde1c),ENSMUSG00000059173(Pde1a),ENSMUSG00000022489(Pde1b)" "ENSG00000154678(PDE1C),ENSG00000115252(PDE1A),ENSG00000123360(PDE1B)" DRSC19489 E 1.426747453 0.815303626 3.050399095 -0.449258615 FBgn0085409 CG34380 http://flybase.net/reports/FBgn0085409.html "FBgn0031789, FBgn0031788, FBgn0031787, FBgn0043510, FBgn0040951, FBgn0051640" protein_coding_gene "0004716=receptor signaling protein tyrosine kinase activity, 0005518=collagen binding" "0007165=signal transduction, 0018108=peptidyl-tyrosine phosphorylation, 0038063=collagen-activated tyrosine kinase receptor signaling pathway" 0005925=focal adhesion "CG31640, CG13987, CG13986, CG15813, CG13988, anon-WO0073329.6" "IPR008979=Galactose-binding domain-like, IPR000421=Coagulation factor 5/8 C-terminal domain" CG34380 16-Dec-15 2015_12 "ENSDARG00000051913(ddr2a),ENSDARG00000058695(ddr2),ENSDARG00000004722" WBGene00016104(ddr-1) "ENSXETG00000023452(),ENSXETG00000004752(DDR2),ENSXETG00000024086(DDR1)" "ENSMUSG00000026674(Ddr2),ENSMUSG00000003534(Ddr1)" "ENSG00000162733(DDR2),ENSG00000137332,ENSG00000204580(DDR1),ENSG00000215522" DRSC02318 EK -1.486106275 -0.624803701 -1.756776163 -1.206051193 1.510738365 -0.133466372 FBgn0035555 CG13720 http://flybase.net/reports/FBgn0035555.html protein_coding_gene CG13720 16-Dec-15 2015_12 viable DRSC08329 IEK 0.37935914 -1.722271873 -1.154269315 2.435433502 0.514395707 1.535596861 FBgn0036935 CG14186 http://flybase.net/reports/FBgn0036935.html protein_coding_gene IPR029409=Transmembrane protein 237 CG14186 16-Dec-15 2015_12 viable DRSC10185 K -0.542647093 0.62756085 -0.444681014 -0.140772232 -1.562416446 -0.454003737 FBgn0033448 hebe hebe http://flybase.net/reports/FBgn0033448.html protein_coding_gene 0008340=determination of adult lifespan CG1623 CG1623 16-Dec-15 2015_12 "viable,long lived" DRSC21614 E 0.170522281 1.014179146 1.663291358 0.450142322 0.433376746 1.16239998 FBgn0036046 Ilp2 Insulin-like peptide 2 http://flybase.net/reports/FBgn0036046.html FBgn0044432 protein_coding_gene "0005158=insulin receptor binding, 0005179=hormone activity" "0030307=positive regulation of cell growth, 0045475=locomotor rhythm, 0030536=larval feeding behavior, 0071333=cellular response to glucose stimulus, 0008361=regulation of cell size, 0030431=sleep, 0007623=circadian rhythm, 0008340=determination of adult lifespan, 0040014=regulation of multicellular organism growth, 0040009=regulation of growth rate, 2000252=negative regulation of feeding behavior, 0040007=growth, 0060250=germ-line stem-cell niche homeostasis, 0009758=carbohydrate utilization, 0008286=insulin receptor signaling pathway, 0040018=positive regulation of multicellular organism growth, 0070328=triglyceride homeostasis, 0060180=female mating behavior" 0005615=extracellular space "dilp-2, Dilp2, Dilp, dIlp2, unnamed, Insulin-related peptide, dILP2, Ilp-2, DILP, insulin-like peptide, Insulin- related peptide 2, ILP2, dilp2, dILP-2, Drosophila insulin-like peptide 2, IRP, DILP-2, CG8167, Ilp, Dilp-2, dilp, insulin-like peptide 2, ilp2, DILP2, insulin-like peptide-2, insulin-like 2, Dilp 2, Drosophila insulin like peptide 2" "IPR022353=Insulin, conserved site, IPR022352=Insulin family, IPR016179=Insulin-like" CG8167 16-Dec-15 2015_12 " larval stage , embryonic stage | stage 12-16 , larval stage | third instar " " larval brain | restricted

, mesoderm

, imaginal disc

ubiquitous , embryonic/larval salivary gland

ubiquitous , embryonic/larval midgut

, larval brain | restricted

anterior & medial " "large body,visible,increased cell number,increased cell size,lethal,chemical resistant,stress response defective,short lived,nutrition conditional,size defective,feeding behavior defective,heat sensitive,viable,developmental rate defective,long lived,mating defective,small body" wing DRSC29688 K 1.026157944 -0.523796378 -0.028547484 0.166272508 -0.633506825 1.772251887 FBgn0030737 CG9914 http://flybase.net/reports/FBgn0030737.html protein_coding_gene "0003857=3-hydroxyacyl-CoA dehydrogenase activity, 0070403=NAD+ binding" "0055114=oxidation-reduction process, 0006631=fatty acid metabolic process" Enoyl-CoA hydratase mitochondrial "IPR016040=NAD(P)-binding domain, IPR006180=3-hydroxyacyl-CoA dehydrogenase, conserved site, IPR013328=6-phosphogluconate dehydrogenase, domain 2, IPR006108=3-hydroxyacyl-CoA dehydrogenase, C-terminal, IPR006176=3-hydroxyacyl-CoA dehydrogenase, NAD binding, IPR008927=6-phosphogluconate dehydrogenase C-terminal domain-like, IPR022694=3-hydroxyacyl-CoA dehydrogenase" CG9914 16-Dec-15 2015_12 ENSDARG00000003675(cryl1) WBGene00022130(Y71F9B.9) ENSXETG00000021105(hadhsc) ENSMUSG00000021947(Cryl1) ENSG00000165475(CRYL1) viable DRSC20216 K 0.407541671 0.68685055 -0.574899697 -0.1670755 1.818331994 0.563133281 FBgn0261963 mid midline http://flybase.net/reports/FBgn0261963.html "FBgn0005511, FBgn0001934, FBgn0002746, FBgn0031706, FBgn0016996, FBgn0065989" protein_coding_gene "0001226=RNA polymerase II transcription corepressor binding, 0003700=sequence-specific DNA binding transcription factor activity, 0001227=RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007402=ganglion mother cell fate determination, 0030381=chorion-containing eggshell pattern formation, 0007399=nervous system development, 0007409=axonogenesis, 0007507=heart development, 0007417=central nervous system development, 0010629=negative regulation of gene expression, 0003015=heart process, 0035223=leg disc pattern formation, 0097156=fasciculation of motor neuron axon, 0051890=regulation of cardioblast differentiation, 0007411=axon guidance, 0042684=cardioblast cell fate commitment, 0042659=regulation of cell fate specification, 0051960=regulation of nervous system development, 0014018=neuroblast fate specification, 0014019=neuroblast development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048665=neuron fate specification, 0035050=embryonic heart tube development, 0008406=gonad development, 0007367=segment polarity determination" 0005634=nucleus "neuromancer 2, extra, nmr2, H15r, lost in space, H15-related, TBX20, neuromancer 1, los, CG6634, Midline, neuromancer2, Mid(H15), H15r/nmr2" "IPR001699=Transcription factor, T-box, IPR018186=Transcription factor, T-box, conserved site, IPR008967=p53-like transcription factor, DNA-binding" CG6634 16-Dec-15 2015_12 ENSDARG00000005150(tbx20) WBGene00003106(mab-9) ENSXETG00000013110(Q3SA46_XENTR) ENSMUSG00000031965(Tbx20) ENSG00000164532(TBX20) " embryonic stage | stage 5 , embryonic stage | stage 14-15 , embryonic stage | stage 15 , embryonic stage | stage 12 , larval stage | third instar " " organism | segment polarity

, embryonic heart

, embryonic brain

, embryonic ventral nervous system

, ventral thoracic disc | ventral & proximal | restricted

" DRSC02977 E 0.654743822 -0.050344335 1.523325418 0.391926409 -0.263649577 0.307618552 FBgn0053904 His2B:CG33904 His2B:CG33904 http://flybase.net/reports/FBgn0053904.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33904 "IPR007125=Histone H2A/H2B/H3, IPR000558=Histone H2B, IPR009072=Histone-fold" CG33904 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0263121 Prosë±1 Proteasome ë±1 subunit http://flybase.net/reports/FBgn0263121.html "FBgn0026781, FBgn0033228, FBgn0065188" protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" "0006974=cellular response to DNA damage stimulus, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0019773=proteasome core complex, alpha-subunit complex, 0000502=proteasome complex, 0005839=proteasome core complex" "20S proteasome subunit alpha1, Proteasome alpha6 subunit, Alpha-1, prosalpha1, alpha-subunit of 20S proteasome, alpha-1, 18495, l(2)SH2342, PSA6_DROME, alpha1, 20s proteasome, Prosalpha6, 20S proteasome, l(2)SH2 2342, prosalpha6, lethal (2) SH2342, CG18495, Prosalpha1" "IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR029055=Nucleophile aminohydrolases, N-terminal, IPR001353=Proteasome, subunit alpha/beta, IPR023332=Proteasome A-type subunit" CG18495 16-Dec-15 2015_12 "ENSDARG00000013966(zgc:92716),ENSDARG00000019398(psma6a)" YGL011C(SCL1) WBGene00003922(pas-1) ENSXETG00000025884(psma6) ENSMUSG00000021024(Psma6) ENSG00000100902(PSMA6) "neuroanatomy defective,lethal,recessive" rhabdomere of eye photoreceptor cell DRSC07515 IEK -2.335959773 -2.87074977 -1.812772388 -1.150262632 1.591377384 1.378424082 FBgn0033226 CG1882 http://flybase.net/reports/FBgn0033226.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0004301=epoxide hydrolase activity" "0005777=peroxisome, 0005811=lipid particle" Abhydrolase 1 "IPR029058=Alpha/Beta hydrolase fold, IPR000073=Alpha/beta hydrolase fold-1, IPR000639=Epoxide hydrolase-like" CG1882 16-Dec-15 2015_12 ENSDARG00000025122(abhd4) "YDR125C(ECM18),YLR099C(ICT1)" WBGene00007711(C25A1.12) "ENSXETG00000008018(abhd4),ENSXETG00000022025(abhd5)" "ENSMUSG00000040997(Abhd4),ENSMUSG00000032540(Abhd5)" "ENSG00000100439(ABHD4),ENSG00000011198(ABHD5)" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0035771 Sec63 Sec63 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0035771.html FBgn0062086 protein_coding_gene "0005047=signal recognition particle binding, 0008565=protein transporter activity" "0031204=posttranslational protein targeting to membrane, translocation" "0005785=signal recognition particle receptor complex, 0045169=fusome" "sec63, CG8583, anon-WO0118547.333, peg" "IPR004179=Sec63 domain, IPR000008=C2 domain, IPR014756=Immunoglobulin E-set, IPR018253=DnaJ domain, conserved site, IPR027137=Translocation protein Sec63, IPR001623=DnaJ domain" CG8583 16-Dec-15 2015_12 ENSDARG00000017740(sec63) YOR254C(SEC63) WBGene00001047(dnj-29) ENSXETG00000014863(SEC63) ENSMUSG00000019802(Sec63) ENSG00000025796(SEC63) "lethal,viable" FBgn0034091 mrj mrj http://flybase.net/reports/FBgn0034091.html protein_coding_gene 0051082=unfolded protein binding 0006457=protein folding "dMRJ, dmrj, MRJ, CG8448" "IPR018253=DnaJ domain, conserved site, IPR001623=DnaJ domain" CG8448 16-Dec-15 2015_12 "ENSDARG00000004680(dnajb6a),ENSDARG00000020953(dnajb6b),ENSDARG00000058644(zgc:153268)" "ENSXETG00000021624(dnajb6),ENSXETG00000019286(TGas070d24.1)" ENSMUSG00000048652(4930503B20Rik) "ENSG00000105993(DNAJB6),ENSG00000172404(DNAJB7),ENSG00000179407(DNAJB8),ENSG00000135924(DNAJB2)" "partially lethal - majority die,visible" mesothoracic tergum FBgn0030863 CG8188 http://flybase.net/reports/FBgn0030863.html "FBtr0074476, FBpp0074250" protein_coding_gene 0004842=ubiquitin-protein transferase activity "0010458=exit from mitosis, 0016567=protein ubiquitination, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0007476=imaginal disc-derived wing morphogenesis" "Ubc, Ube2S" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site" CG8188 16-Dec-15 2015_12 ENSDARG00000031775(zgc:114060) "ENSXETG00000000138(ube2s),ENSXETG00000000140()" ENSMUSG00000060860(Ube2s) ENSG00000108106(UBE2S) "viable,fertile" FBgn0033100 CG3420 http://flybase.net/reports/FBgn0033100.html FBgn0047109 protein_coding_gene "0051537=2 iron, 2 sulfur cluster binding" 0043231=intracellular membrane-bounded organelle BcDNA:RE40412 "IPR006622=Iron sulphur-containing domain, CDGSH-type, subfamily, IPR018967=Iron sulphur-containing domain, CDGSH-type" CG3420 16-Dec-15 2015_12 ENSMUSG00000078695(Cisd3) "partially lethal - majority die,some die during pupal stage" FBgn0085419 Rgk2 "Rad, Gem/Kir family member 2" http://flybase.net/reports/FBgn0085419.html "FBgn0034357, FBgn0050119" protein_coding_gene "0005525=GTP binding, 0003924=GTPase activity" "1901386=negative regulation of voltage-gated calcium channel activity, 0007264=small GTPase mediated signal transduction, 0015031=protein transport" "0016020=membrane, 0005622=intracellular" "Rgk2, CG30119, CG15069, CG34390, RGK2" "IPR003579=Small GTPase superfamily, Rab type, IPR020849=Small GTPase superfamily, Ras type, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003578=Small GTPase superfamily, Rho type, IPR001806=Small GTPase superfamily" CG34390 16-Dec-15 2015_12 "ENSDARG00000052011(rrad),ENSDARG00000020544(rem1),ENSDARG00000029112(gem)" WBGene00013124(Y52B11A.4) "ENSXETG00000013757(REM2),ENSXETG00000017408(rrad),ENSXETG00000014678(GEM),ENSXETG00000024013(REM1)" "ENSG00000166592(RRAD),ENSG00000164949(GEM),ENSG00000139890(REM2)" viable FBgn0033883 CG16935 http://flybase.net/reports/FBgn0033883.html protein_coding_gene "0008270=zinc ion binding, 0019166=trans-2-enoyl-CoA reductase (NADPH) activity" "0055114=oxidation-reduction process, 0006631=fatty acid metabolic process" "0005739=mitochondrion, 0005875=microtubule associated complex" DM_7303260 "IPR002085=Alcohol dehydrogenase superfamily, zinc-type, IPR011032=GroES-like, IPR013149=Alcohol dehydrogenase, C-terminal, IPR016040=NAD(P)-binding domain" CG16935 16-Dec-15 2015_12 "ENSDARG00000032326(LOC100330042),ENSDARG00000033587" YBR026C(ETR1) WBGene00012375(mecr-1) "ENSXETG00000014371(mecr),ENSXETG00000014908()" ENSMUSG00000028910(Mecr) ENSG00000116353(MECR) FBgn0039631 Sirt7 Sirtuin 7 http://flybase.net/reports/FBgn0039631.html protein_coding_gene 0070403=NAD+ binding 0005634=nucleus "CG11305, D.mel5, dSIRT7, Sirt7, dmSRT409, SIRT7" "IPR003000=Sirtuin family, IPR026590=Sirtuin family, catalytic core domain, IPR029035=DHS-like NAD/FAD-binding domain" CG11305 16-Dec-15 2015_12 ENSDARG00000060645(LOC796135) ENSMUSG00000025138(Sirt7) "ENSG00000187531(SIRT7),ENSG00000218591" "viable,fertile" FBgn0016685 Nlp Nucleoplasmin http://flybase.net/reports/FBgn0016685.html FBgn0016133 protein_coding_gene "0042393=histone binding, 0003676=nucleic acid binding, 0042623=ATPase activity, coupled" "0016584=nucleosome positioning, 0035041=sperm chromatin decondensation, 0006338=chromatin remodeling" "0005634=nucleus, 0005737=cytoplasm, 0005654=nucleoplasm, 0005730=nucleolus" "dNLP, Crp1, nlp, CRP1, nucleophosmin, CG7917, dNLP-S, NLP, p22, nucleoplasmin-1, Chromatin decondensation protein 1, Nucleoplasmin-like" "IPR004301=Nucleoplasmin, IPR024057=Nucleoplasmin core domain" CG7917 16-Dec-15 2015_12 "ENSDARG00000053963(npm2),ENSDARG00000071886,ENSDARG00000056794(npm3)" "ENSXETG00000014472(npm3),ENSXETG00000008403(npm1),ENSXETG00000010542(npm2),ENSXETG00000016499()" "ENSMUSG00000047911(Npm2),ENSMUSG00000057113(Npm1),ENSMUSG00000056209(Npm3)" "ENSG00000107833(NPM3),ENSG00000158806(NPM2)" embryonic stage -- adult stage embryonic stage -- adult stage viable FBgn0025936 Eph Eph receptor tyrosine kinase http://flybase.net/reports/FBgn0025936.html "FBgn0015726, FBgn0023093" protein_coding_gene "0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0005003=ephrin receptor activity, 0005524=ATP binding" "0016319=mushroom body development, 0006468=protein phosphorylation, 0007409=axonogenesis, 0007165=signal transduction, 0048013=ephrin receptor signaling pathway, 0035011=melanotic encapsulation of foreign target, 0007422=peripheral nervous system development" "0005886=plasma membrane, 0005887=integral component of plasma membrane" "Eph receptor, Eph kinase, Dek, dek, Deph, CG1511, Drosophila eph, CT3831, Ephrin receptors, DEK, eph, lincRNA.923, RPTK Dek7, Dek7, Ek7" "IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR027936=Ephrin receptor, transmembrane domain, IPR008979=Galactose-binding domain-like, IPR003961=Fibronectin type III, IPR017441=Protein kinase, ATP binding site, IPR013783=Immunoglobulin-like fold, IPR001426=Tyrosine-protein kinase, receptor class V, conserved site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR013761=Sterile alpha motif/pointed domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR016257=Ephrin receptor type-A /type-B, IPR001660=Sterile alpha motif domain, IPR008266=Tyrosine-protein kinase, active site, IPR001090=Ephrin receptor ligand binding domain" CG1511 16-Dec-15 2015_12 "ENSDARG00000021539,ENSDARG00000037373(LOC562176),ENSDARG00000033589(LOC555957),ENSDARG00000060760,ENSDARG00000054454(epha4a),ENSDARG00000004635(epha7),ENSDARG00000010767(rtk4),ENSDARG00000020080(ek1),ENSDARG00000023609(si:ch211-122l14.1),ENSDARG00000040346(ephb4a),ENSDARG00000027112(rtk8),ENSDARG00000031548(ek3),ENSDARG00000022971(si:ch211-247c17.1),ENSDARG00000057729(LOC572411),ENSDARG00000011600(epha4b),ENSDARG00000039373(si:ch211-176k6.1),ENSDARG00000017354(rtk6)" WBGene00006868(vab-1) "ENSXETG00000007614(EPHA4),ENSXETG00000018943(),ENSXETG00000018746(EPHA7),ENSXETG00000017584(EPHA6),ENSXETG00000017293(EPHB3),ENSXETG00000013722(Q66KB3_XENTR)" "ENSMUSG00000032537,ENSMUSG00000028664(Ephb2),ENSMUSG00000005958(Ephb3),ENSMUSG00000026235(Epha4),ENSMUSG00000028289(Epha7),ENSMUSG00000029245(Epha5),ENSMUSG00000052504(Epha3),ENSMUSG00000029710(Ephb4),ENSMUSG00000055540(Epha6),ENSMUSG00000028661(Epha8),ENSMUSG00000029869(Ephb6),ENSMUSG00000006445(Epha2)" "ENSG00000154928(EPHB1),ENSG00000133216(EPHB2),ENSG00000182580(EPHB3),ENSG00000116106(EPHA4),ENSG00000135333(EPHA7),ENSG00000145242(EPHA5),ENSG00000044524(EPHA3),ENSG00000196411(EPHB4),ENSG00000080224(EPHA6),ENSG00000070886(EPHA8),ENSG00000106123(EPHB6),ENSG00000142627(EPHA2)" "viable,recessive,fertile,neuroanatomy defective,immune response defective,partially lethal - majority die,female semi-sterile,learning defective,visible,some die during pupal stage" "vertical lobe of adult mushroom body,somatic clone,medial lobe of adult mushroom body,medulla neuropil,lobula,cell body rind of medulla,cell body rind of lobula plate,photoreceptor & axon,commissure,longitudinal connective,embryonic/larval neuron,photoreceptor cell & axoney.PH,embryonic/larval optic lobe,photoreceptor cell R7 & axon | somatic cloneë±Tub84B.PP,photoreceptor cell R8 & axon | somatic cloneë±Tub84B.PP,photoreceptor cell & axonbi-md653,fascicle" FBgn0034606 ASPP "Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein" http://flybase.net/reports/FBgn0034606.html protein_coding_gene 0030296=protein tyrosine kinase activator activity 0061098=positive regulation of protein tyrosine kinase activity 0005912=adherens junction "Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein, dASPP, Ankyrin-repeat, SH3-domain and Proline-rich-region containing Protein, CG18375" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR001452=SH3 domain" CG18375 16-Dec-15 2015_12 "ENSDARG00000009142(ppp1r13b),ENSDARG00000004377,ENSDARG00000054939,ENSDARG00000054858(si:dkeyp-34c12.2),ENSDARG00000009136(tp53bp2)" WBGene00000146(ape-1) "ENSXETG00000018593(tp53bp2),ENSXETG00000023064(PPP1R13B)" "ENSMUSG00000021285(Ppp1r13b),ENSMUSG00000026510(Trp53bp2)" "ENSG00000143514(TP53BP2),ENSG00000088808(PPP1R13B)" "visible,increased cell number,partially lethal - majority die,some die during pupal stage" "eye,interommatidial bristle,ommatidium,wing" FBgn0000567 Eip74EF Ecdysone-induced protein 74EF http://flybase.net/reports/FBgn0000567.html "FBgn0011459, FBgn0026806, FBgn0036739, FBgn0052180" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0006914=autophagy, 0008219=cell death, 0035071=salivary gland cell autophagic cell death, 0040034=regulation of development, heterochronic, 0048477=oogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "mE74, Eip74A, CG32180, l(3)24, eip74EF, l(3)neo24, E74-B, e74B, E-74, Eip74E, E74A, e74, CG6273, ecdysone inducible protein, 3.3, CG6285, eip74ef, Ecdysone-induced-protein 74EF, ecdysone induced protein 74EF, E74, Eip74, E74B, 74EF, E74A/B, ECIP, Eip74 A, Ecdysone-induced prot 74EF, ecdysone-induced protein 74EF" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000418=Ets domain" CG32180 16-Dec-15 2015_12 WBGene00016029(C24A1.2) " prepupal stage , prepupal stage | stage P4 , prepupal stage | stage P1-3 " organism

"lethal,recessive,lethal - all die before end of P-stage,some die during P-stage,decreased cell death,some die during pharate adult stage,viable,short lived,heat sensitive,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage" "adult epidermis,embryonic/larval salivary gland,salivary gland,embryonic/larval midgut,adult brain,heat sensitive,larva,cuticle,air bubble,anterior pupal spiracle,procephalic segment" DRSC11160 EK -0.828445662 1.013755812 -1.067100211 1.896715567 1.612593245 1.384300016 FBgn0031462 CG2964 http://flybase.net/reports/FBgn0031462.html protein_coding_gene "0004743=pyruvate kinase activity, 0000287=magnesium ion binding, 0030955=potassium ion binding" "0006096=glycolytic process, 0006090=pyruvate metabolic process" "0005737=cytoplasm, 0005886=plasma membrane" "IPR015813=Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR015806=Pyruvate kinase, beta-barrel insert domain, IPR015795=Pyruvate kinase, C-terminal, IPR015793=Pyruvate kinase, barrel, IPR011037=Pyruvate kinase-like, insert domain, IPR001697=Pyruvate kinase, IPR015794=Pyruvate kinase, alpha/beta" CG2964 16-Dec-15 2015_12 viable DRSC00554 IE 1.544119628 0.31574268 1.707965517 0.693171021 -0.097376394 0.096081655 FBgn0064115 CG33649 http://flybase.net/reports/FBgn0064115.html "FBgn0053084, FBgn0053649, FBtr0089832, FBtr0089833, FBpp0088774" protein_coding_gene 0006450=regulation of translational fidelity "CG33084, CG33084-ORFA, CG8969" "IPR003837=Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit" CG33649 16-Dec-15 2015_12 ENSDARG00000056855(si:rp71-1c23.3) WBGene00013433(Y66D12A.7) ENSMUSG00000029536(Gatc) ENSG00000111780 DRSC03312 K 0.629697649 0.082733741 -0.021964253 0.19911291 -1.747062379 0.398493618 FBgn0003275 RpII18 RNA polymerase II 18kD subunit http://flybase.net/reports/FBgn0003275.html "FBgn0014025, FBgn0064834" protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding" "0006366=transcription from RNA polymerase II promoter, 0007095=mitotic G2 DNA damage checkpoint" "0005665=DNA-directed RNA polymerase II, core complex" "RPB6_DROME, RNA polII, RNA pol II, pol II, RNA-polymerase ABC 14kD subunit, RNA Pol II, RpABC14, RNAP, RNA polymerase II (18-kDa subunit), H5, Rpll18, Pol II, Dm6, RNA polymerase II, RNApolII, PolII, RPII18, RNAP II, BcDNA:RH21608, polII, CG1163" "IPR020708=DNA-directed RNA polymerase, 14-18kDa subunit, conserved site, IPR028363=DNA-directed RNA polymerase, subunit RPB6, IPR012293=RNA polymerase subunit, RPB6/omega, IPR006110=RNA polymerase, subunit omega/K/RPB6, IPR006111=Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit" CG1163 16-Dec-15 2015_12 ENSDARG00000036625(LOC791979) YPR187W(RPO26) WBGene00007355(rpb-6) ENSXETG00000006346(polr2f) ENSMUSG00000033020(Polr2f) ENSG00000100142(POLR2F) DRSC12366 EK -1.366366063 0.659408359 1.642265617 -2.729166885 2.364746673 2.379237881 FBgn0025582 Int6 Int6 homologue http://flybase.net/reports/FBgn0025582.html "FBgn0010945, FBgn0011424" protein_coding_gene 0003743=translation initiation factor activity "0006413=translational initiation, 0051726=regulation of cell cycle, 0048812=neuron projection morphogenesis, 0006909=phagocytosis" "0005852=eukaryotic translation initiation factor 3 complex, 0005829=cytosol, 0043231=intracellular membrane-bounded organelle" "eIF-3p48/INT-6, l(3)j9E8, eIF3-S6, CG9677, BcDNA:GM01233, BcDNA.GM01233, eIF3-p48/INT6, l(3)10547, DINT6, eIF3e" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019010=Eukaryotic translation initiation factor 3 subunit E, N-terminal, IPR016650=Eukaryotic translation initiation factor 3 subunit E, IPR000717=Proteasome component (PCI) domain" CG9677 16-Dec-15 2015_12 "ENSDARG00000002549(eif3eb),ENSDARG00000057603" WBGene00001228(eif-3.E) ENSXETG00000003602(eif3s6) ENSMUSG00000022336(Eif3e) ENSG00000104408(EIF3E) embryonic stage -- adult stage embryonic stage -- adult stage "lethal,recessive,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,decreased cell number,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "female germline cell,germline clone,eye disc,somatic clone,wing disc,embryonic/larval brain" DRSC11199 EK -0.892382533 -1.268805357 -2.195370958 -3.944155929 -1.99799344 1.192092456 FBgn0264308 CG43778 http://flybase.net/reports/FBgn0264308.html "FBgn0264300, FBgn0032504, FBgn0032502" protein_coding_gene 0016020=membrane "CG16970, FBgn 32504, CG15639" CG43778 16-Dec-15 2015_12 DRSC02549 E -0.759469167 0.045410406 0.854940605 -2.264219618 -0.583766922 0.492816467 FBgn0266722 Trs33 TRAPP subunit 33 ortholog (S. cerevisiae) http://flybase.net/reports/FBgn0266722.html "FBgn0044804, FBgn0038323, FBgn0047020" protein_coding_gene "0016192=vesicle-mediated transport, 0006888=ER to Golgi vesicle-mediated transport" 0030008=TRAPP complex "Trs33p, Trs33, BcDNA:RH37427, CG6196" "IPR024096=NO signalling/Golgi transport ligand-binding domain, IPR007194=Transport protein particle (TRAPP) component" CG6196 16-Dec-15 2015_12 "ENSDARG00000016463(trappc6b),ENSDARG00000033171(trappc6bl)" WBGene00010699(K08H10.9) "ENSXETG00000015782(TRAPPC6B),ENSXETG00000019038(trappc6b)" ENSMUSG00000020993(Trappc6b) ENSG00000182400(TRAPPC6B) FBgn0053832 His2A:CG33832 His2A:CG33832 http://flybase.net/reports/FBgn0053832.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33832 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR002119=Histone H2A" CG33832 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0053868 His2B:CG33868 His2B:CG33868 http://flybase.net/reports/FBgn0053868.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33868 "IPR007125=Histone H2A/H2B/H3, IPR000558=Histone H2B, IPR009072=Histone-fold" CG33868 16-Dec-15 2015_12 "ENSDARG00000070285,ENSDARG00000068996(hist2h2l),ENSDARG00000052442,ENSDARG00000070289(LOC560974),ENSDARG00000051724(LOC563569),ENSDARG00000067937,ENSDARG00000034203(LOC100333496),ENSDARG00000070297(LOC561322),ENSDARG00000067739,ENSDARG00000067934,ENSDARG00000038324(zgc:114046),ENSDARG00000068043,ENSDARG00000052446,ENSDARG00000068058,ENSDARG00000067884,ENSDARG00000071834,ENSDARG00000068055,ENSDARG00000063055,ENSDARG00000038327,ENSDARG00000070250,ENSDARG00000068061,ENSDARG00000051778,ENSDARG00000038326,ENSDARG00000039547,ENSDARG00000051726,ENSDARG00000038325,ENSDARG00000051721,ENSDARG00000052434,ENSDARG00000067888,ENSDARG00000036918,ENSDARG00000060852,ENSDARG00000070254(LOC100005210)" "YDR224C(HTB1),YBL002W(HTB2)" "WBGene00001918(his-44),WBGene00001932(his-58),WBGene00001915(his-41),WBGene00001896(his-22),WBGene00001878(his-4),WBGene00001928(his-54)" "ENSXETG00000027131(hist2h2bf),ENSXETG00000026742(),ENSXETG00000026114(hist2h2bf),ENSXETG00000024979(hist2h2bf),ENSXETG00000027853(hist2h2bf),ENSXETG00000026113(hist2h2bf),ENSXETG00000025962(hist2h2bf),ENSXETG00000027146(hist2h2bf),ENSXETG00000025966(hist2h2bf),ENSXETG00000026069(hist2h2bf),ENSXETG00000026074(hist2h2bf),ENSXETG00000024972(hist2h2bf),ENSXETG00000027148(hist2h2bf),ENSXETG00000025958(hist2h2bf),ENSXETG00000024980(hist2h2bf),ENSXETG00000027965(),ENSXETG00000027198(),ENSXETG00000012439(),ENSXETG00000026736(),ENSXETG00000026731(),ENSXETG00000026680(),ENSXETG00000026064(),ENSXETG00000027848(),ENSXETG00000025930(Q6AZK7_XENTR),ENSXETG00000026070(Q6AZK7_XENTR),ENSXETG00000027578(),ENSXETG00000027775(),ENSXETG00000025395(),ENSXETG00000027177(),ENSXETG00000025566(),ENSXETG00000027189(),ENSXETG00000026678(),ENSXETG00000027958(),ENSXETG00000027182(),ENSXETG00000027502(),ENSXETG00000027199(),ENSXETG00000027172(),ENSXETG00000026669(),ENSXETG00000026963(hist1h2bk),ENSXETG00000025796(hist1h2bk),ENSXETG00000000627(hist1h2bk),ENSXETG00000027508(hist1h2bk),ENSXETG00000026971(hist1h2bk),ENSXETG00000026967(hist1h2bk),ENSXETG00000027233(hist1h2bk),ENSXETG00000008297(),ENSXETG00000011632()" "ENSMUSG00000047246(Hist1h2be),ENSMUSG00000018102(Hist1h2bc),ENSMUSG00000075031(Hist1h2bb),ENSMUSG00000058189(Hist1h2bm),ENSMUSG00000058385(Hist1h2bg),ENSMUSG00000069268(Hist1h2bf),ENSMUSG00000069300(Hist1h2bj),ENSMUSG00000069303,ENSMUSG00000069307(Gm13646),ENSMUSG00000069314(Hist1h2bl),ENSMUSG00000069271(Hist1h2bn),ENSMUSG00000062727(Hist1h2bk),ENSMUSG00000064168(Hist1h2bh),ENSMUSG00000056895(Hist3h2ba),ENSMUSG00000068854(Hist2h2be),ENSMUSG00000050799(Hist1h2ba)" "ENSG00000203814(HIST2H2BF),ENSG00000197846(HIST1H2BF),ENSG00000187990(HIST1H2BG),ENSG00000197697(HIST1H2BE),ENSG00000180596(HIST1H2BC),ENSG00000185130(HIST1H2BL),ENSG00000220323,ENSG00000196331(HIST1H2BO),ENSG00000196374(HIST1H2BM),ENSG00000158373(HIST1H2BD),ENSG00000196226(HIST1H2BB),ENSG00000197459(HIST1H2BH),ENSG00000184678(HIST2H2BE),ENSG00000168242(HIST1H2BI),ENSG00000197903(HIST1H2BK),ENSG00000124635(HIST1H2BJ),ENSG00000196890(HIST3H2BB),ENSG00000146047(HIST1H2BA)" FBgn0037612 CG8112 http://flybase.net/reports/FBgn0037612.html protein_coding_gene "0034736=cholesterol O-acyltransferase activity, 0004772=sterol O-acyltransferase activity" "0034435=cholesterol esterification, 0042632=cholesterol homeostasis" 0016020=membrane "IPR030687=Sterol O-acyltransferase, metazoa, IPR004299=Membrane bound O-acyl transferase, MBOAT, IPR014371=Sterol O-acyltransferase, ACAT/DAG/ARE types" CG8112 16-Dec-15 2015_12 ENSDARG00000062297(LOC564424) WBGene00007174(mboa-1) "ENSXETG00000023234(SOAT1),ENSXETG00000001821(SOAT2)" "ENSMUSG00000026600(Soat1),ENSMUSG00000023045(Soat2)" "ENSG00000057252(SOAT1),ENSG00000167780(SOAT2)" viable FBgn0022981 rpk ripped pocket http://flybase.net/reports/FBgn0022981.html protein_coding_gene "0005272=sodium channel activity, 0015280=ligand-gated sodium channel activity" "0050975=sensory perception of touch, 0050966=detection of mechanical stimulus involved in sensory perception of pain, 0006814=sodium ion transport" "0043025=neuronal cell body, 0016021=integral component of membrane, 0030425=dendrite, 0030424=axon" "CG1058, RPK, gonad-specific amiloride-sensitive sodium channel 1, dGNaC1, ppk2, GNaC1" "IPR001873=Na+ channel, amiloride-sensitive, IPR020903=Na+ channel, amiloride-sensitive, conserved site" CG1058 16-Dec-15 2015_12 "ENSDARG00000004243(accn4b),ENSDARG00000027512(accn2a),ENSDARG00000068245,ENSDARG00000008329(accn2b),ENSDARG00000025162,ENSDARG00000037880(accn1),ENSDARG00000006849(LOC100331792)" "WBGene00003174(mec-10),WBGene00003168(mec-4),WBGene00000950(deg-1),WBGene00012137(asic-2)" "ENSXETG00000022398(ACCN5),ENSXETG00000013366(ACCN3),ENSXETG00000014229(ACCN1)" "ENSMUSG00000020704(Accn1),ENSMUSG00000023017(Accn2),ENSMUSG00000038276(Accn3),ENSMUSG00000033007(Accn4),ENSMUSG00000028008(Accn5)" "ENSG00000162572(SCNN1D),ENSG00000111319(SCNN1A),ENSG00000213199(ACCN3),ENSG00000110881(ACCN2),ENSG00000108684(ACCN1),ENSG00000072182(ACCN4),ENSG00000023843(ACCN5)" " embryonic stage&&adult stage , adult stage , oogenesis stage | stage S10 , oogenesis stage | stage >=S5 , adult stage | male , spermatogenesis && adult stage , embryonic stage | 0-3 hr , embryonic stage | 0-4 hr , embryonic stage | stage <=8 " " ovary

, nurse cell

, seminal vesicle

, gonad

, oocyte

, follicle cell

, primary spermatocyte cyst

" "touch sensitivity defective,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,viable" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0030747 CG4301 http://flybase.net/reports/FBgn0030747.html protein_coding_gene "0005524=ATP binding, 0004012=phospholipid-translocating ATPase activity, 0000287=magnesium ion binding" 0045332=phospholipid translocation 0016021=integral component of membrane DmCG4301 "IPR023214=HAD-like domain, IPR008250=P-type ATPase, A domain, IPR018303=P-type ATPase, phosphorylation site, IPR001757=P-type ATPase, IPR023299=P-type ATPase, cytoplasmic domain N, IPR006539=P-type ATPase, subfamily IV" CG4301 16-Dec-15 2015_12 "ENSDARG00000054028(si:dkey-211e20.10),ENSDARG00000008413(si:dkey-251i8.1),ENSDARG00000036442(atp11c)" "ENSXETG00000016814(ATP11B),ENSXETG00000001905(ATP11A),ENSXETG00000018290(ATP11C)" "ENSMUSG00000037400(Atp11b),ENSMUSG00000031441(Atp11a),ENSMUSG00000062949(Atp11c)" "ENSG00000058063(ATP11B),ENSG00000068650(ATP11A),ENSG00000101974(ATP11C)" "viable,body color defective" mesothoracic tergum FBgn0053850 His2A:CG33850 His2A:CG33850 http://flybase.net/reports/FBgn0053850.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33850 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR002119=Histone H2A" CG33850 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0035271 CG2021 http://flybase.net/reports/FBgn0035271.html protein_coding_gene 0044822=poly(A) RNA binding "0000398=mRNA splicing, via spliceosome" "0005681=spliceosomal complex, 0005688=U6 snRNP, 0030532=small nuclear ribonucleoprotein complex, 0071011=precatalytic spliceosome" "IPR010920=LSM domain, IPR001163=LSM domain, eukaryotic/archaea-type" CG2021 16-Dec-15 2015_12 YJR022W(LSM8) WBGene00003082(lsm-8) ENSXETG00000021829(LSM8) ENSMUSG00000044155(Naa38) ENSG00000128534(NAA38) FBgn0261710 nocte no circadian temperature entrainment http://flybase.net/reports/FBgn0261710.html "FBgn0084287, FBgn0030205" protein_coding_gene "0010378=temperature compensation of the circadian clock, 0009649=entrainment of circadian clock" CG17255 "IPR009738=BAT2, N-terminal" CG17255 16-Dec-15 2015_12 ENSDARG00000031494(nfkbil1) ENSXETG00000002501(BAT2) "ENSMUSG00000040225(Bat2l2),ENSMUSG00000024393(Bat2)" "ENSG00000204469(PRRC2A),ENSG00000206427,ENSG00000206318,ENSG00000117523(PRRC2C),ENSG00000130723(PRRC2B)" DRSC18123 K -0.44634418 -0.530876368 0.170300358 -1.48619864 1.70769046 1.436671064 FBgn0053895 His4:CG33895 His4:CG33895 http://flybase.net/reports/FBgn0053895.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33895 "IPR009072=Histone-fold, IPR019809=Histone H4, conserved site, IPR001951=Histone H4" CG33895 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0004057 Zw Zwischenferment http://flybase.net/reports/FBgn0004057.html protein_coding_gene "0004345=glucose-6-phosphate dehydrogenase activity, 0050661=NADP binding" "0051156=glucose 6-phosphate metabolic process, 0006006=glucose metabolic process, 0006098=pentose-phosphate shunt, 0006739=NADP metabolic process, 0055114=oxidation-reduction process" "Glucose-6-phosphate dehydrogenase, CG12529, G6PDH, G6-PD, G-6pd, G6pdh, glucose-6-phosphate dehydrogenase, G6PD, zw, G-6-PD, Glucose-6-phosphate DH, G6pd, G-6-pdh, G6-pd, G-6PD, g6pd, glucose-6-phosphate 1dehydrogenase" "IPR019796=Glucose-6-phosphate dehydrogenase, active site, IPR001282=Glucose-6-phosphate dehydrogenase, IPR016040=NAD(P)-binding domain, IPR022674=Glucose-6-phosphate dehydrogenase, NAD-binding, IPR022675=Glucose-6-phosphate dehydrogenase, C-terminal" CG12529 16-Dec-15 2015_12 "ENSDARG00000001274(LOC100148915),ENSDARG00000071065(wu:fj78b06)" YNL241C(ZWF1) WBGene00007108(gspd-1) ENSXETG00000012078(H6PD) "ENSMUSG00000031400(G6pdx),ENSMUSG00000081028(G6pd2)" ENSG00000160211(G6PD) adult stage "long lived,oxidative stress response defective,female fertile,lethal,electrophoretic variant,viable,body color defective" mesothoracic tergum DRSC20303 K -0.424696214 -0.02958462 -0.679454002 -0.353407642 0.317753808 1.661294432 FBgn0026372 RpL23A Ribosomal protein L23A http://flybase.net/reports/FBgn0026372.html "FBgn0014878, FBgn0025226, FBgn0025992" protein_coding_gene "0003735=structural constituent of ribosome, 0000166=nucleotide binding" "0051298=centrosome duplication, 0006412=translation" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "anon-EST:fe2D1, L23a, unnamed, rpL25, anon-EST:Liang-1.4, Ribosomal protein L25, RpL23a, RpL25, RPL23a, L23A, Rp L23A, clone 1.4, PBP-3, rpl23a, CG7977, PARP-binding protein-3, 153215_at, Ribosomal protein L23a, anon-fast-evolving-2D1" "IPR013025=Ribosomal protein L25/L23, IPR001014=Ribosomal protein L23/L25, conserved site, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR012678=Ribosomal protein L23/L15e core domain, IPR005633=Ribosomal protein L23/L25, N-terminal" CG7977 16-Dec-15 2015_12 ENSDARG00000006316(rpl23a) "WBGene00004438(rpl-25.1),WBGene00004439(rpl-25.2)" ENSXETG00000026189(rpl23a) "ENSMUSG00000058546(Rpl23a),ENSMUSG00000063556(Gm10132),ENSMUSG00000071532(Gm10335),ENSMUSG00000078126(Rpl23a-ps3),ENSMUSG00000074857(Gm8137),ENSMUSG00000074858(Gm8264),ENSMUSG00000074854(Gm8290),ENSMUSG00000078180,ENSMUSG00000074856(Gm8158),ENSMUSG00000074859(Gm8112),ENSMUSG00000057499(Gm6177),ENSMUSG00000078289,ENSMUSG00000078291(Gm3940),ENSMUSG00000070896(Rpl23a-ps1),ENSMUSG00000078380(Gm6096),ENSMUSG00000074189(Gm5116),ENSMUSG00000078383(Gm6666),ENSMUSG00000074188(Gm5058),ENSMUSG00000062536(Gm6003),ENSMUSG00000078381(Gm5329)" ENSG00000198242(RPL23A) "viable,fertile" DRSC08694 IEK -2.589151873 -1.441711742 -0.404329904 -4.032673527 1.797411205 4.89635514 FBgn0262699 rap retina aberrant in pattern http://flybase.net/reports/FBgn0262699.html "FBgn0003200, FBgn0020547, FBgn0029059, FBgn0040176, FBgn0066831, FBgn0026624" protein_coding_gene 0090302=APC-Cdc20 complex activity "0031536=positive regulation of exit from mitosis, 0008054=negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation, 0031145=anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, 0030163=protein catabolic process, 0010001=glial cell differentiation, 0001745=compound eye morphogenesis, 0008347=glial cell migration, 0007088=regulation of mitotic nuclear division, 0010458=exit from mitosis, 0007455=eye-antennal disc morphogenesis" "0030424=axon, 0005814=centriole, 0005819=spindle, 0005737=cytoplasm, 0005813=centrosome, 0005680=anaphase-promoting complex" "westfalenexpress, Cdh[Fzr], rap/Fzr, APC/C[Fzr/Cdh1], Fzr/rap, dFZR, Hec/Cdh[Fzr], reduced axons, fizzy-related, Rap/Fzr, l(1)G0326, fzr/Cdh1, wex, Fizzy-related/Cdh1, Cdh1[Fzr], Fzr, fzr, Fizzy related, Fxr, cdh1, rap/fizzy-related, rap/fzr, l(1)G0418, redax, Cdh1/Fzr, Cdh1, CDH1, anon-WO03040301.193, Fizzy-related, CG3000" "IPR019775=WD40 repeat, conserved site, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG3000 16-Dec-15 2015_12 "ENSDARG00000015254(fzr1),ENSDARG00000022810(LOC100148604)" YGL003C(CDH1) WBGene00001510(fzr-1) ENSXETG00000006397(fzr1) ENSMUSG00000020235(Fzr1) ENSG00000105325(FZR1) " adult stage , embryonic stage | stage 11 , embryonic stage | syncytial blastoderm " " spermatocyte

, posterior midgut proper primordium

, anterior midgut proper primordium

, salivary gland body primordium

" embryonic stage salivary gland body primordium

DRSC28236 K 0.660458959 0.63595635 0.512118996 0.771260473 -1.776595119 -1.40118134 FBgn0039218 Rpb10 Rpb10 http://flybase.net/reports/FBgn0039218.html FBgn0062890 protein_coding_gene "0003899=DNA-directed RNA polymerase activity, 0003677=DNA binding, 0008270=zinc ion binding" "0006351=transcription, DNA-templated, 0006366=transcription from RNA polymerase II promoter" "0005634=nucleus, 0005665=DNA-directed RNA polymerase II, core complex" "BcDNA:SD08670, RPB10, CG13628" "IPR009057=Homeodomain-like, IPR023580=RNA polymerase subunit RPB10, IPR000268=DNA-directed RNA polymerase, subunit N/Rpb10, IPR020789=RNA polymerases, subunit N, zinc binding site" CG13628 16-Dec-15 2015_12 ENSDARG00000058349(zgc:112305) YOR210W(RPB10) WBGene00021347(rpb-10) "ENSXETG00000002878(POLR2L),ENSXETG00000025768(polr2l)" ENSMUSG00000038489 ENSG00000177700(POLR2L) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC14630 IK -2.341387531 3.983453064 0.168190416 -0.626602177 2.628506925 1.551170702 FBgn0034181 CG8963 http://flybase.net/reports/FBgn0034181.html protein_coding_gene 0003723=RNA binding "0048854=brain morphogenesis, 0042048=olfactory behavior, 0031987=locomotion involved in locomotory behavior, 0002121=inter-male aggressive behavior, 0001964=startle response" "IPR003890=MIF4G-like, type 3, IPR016021=MIF4G-like domain, IPR016024=Armadillo-type fold" CG8963 16-Dec-15 2015_12 ENSDARG00000042892(paip1) ENSMUSG00000025451(Paip1) ENSG00000172239(PAIP1) "smell perception defective,viable,behavior defective,recessive,visible,body color defective,partially lethal - majority die,some die during pupal stage" "wing,mesothoracic tergum" DRSC07302 IEK -0.181245039 -3.014895155 -0.670909515 -3.515190922 0.023378029 1.613646248 FBgn0265595 CG44422 http://flybase.net/reports/FBgn0265595.html "FBgn0083980, FBan0011105, FBgn0261569, FBgn0030282, FBgn0030281" protein_coding_gene 0005509=calcium ion binding "CG34144, CG11105, Dm_X:57642, CG42683, CG12625" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR028846=Recoverin family" CG44422 16-Dec-15 2015_12 ENSXETG00000018462(NKD1) "ENSG00000140807(NKD1),ENSG00000145506(NKD2)" DRSC19380 K 0.547914771 0.809477691 -1.038484854 -0.04790036 -0.101613097 1.563859101 FBgn0035859 CG13678 http://flybase.net/reports/FBgn0035859.html FBgn0047144 protein_coding_gene BcDNA:RE24439 CG13678 16-Dec-15 2015_12 viable DRSC10036 K -1.477587327 1.159264653 0.04160639 0.045127567 -1.640368878 -1.130504683 FBgn0086710 RpL30 Ribosomal protein L30 http://flybase.net/reports/FBgn0086710.html "FBgn0065884, FBgn0010478, FBgn0062959, FBgn0047143, FBgn0032738, FBgn0025257, FBgn0015745" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0051298=centrosome duplication, 0000022=mitotic spindle elongation, 0040007=growth" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "anon-fast-evolving-1D4, Rp L30, L30, BcDNA:RE25263, l(2)SH0229, RPL30, CG10652, anon-EST:fe1D4, BcDNA:RH09938, l(2)SH2 0229, Ribosomal protein L30, Rpl30, plume, l(2)k09918, l(2)01265, L30 ribosomal gene, lethal (2) SH0229, unnamed" "IPR022991=Ribosomal protein L30e, conserved site, IPR000231=Ribosomal protein L30e, IPR004038=Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064=50S ribosomal protein L30e-like" CG10652 16-Dec-15 2015_12 ENSDARG00000035871(rpl30) YGL030W(RPL30) WBGene00004444(rpl-30) "ENSMUSG00000062582(Rpl30-ps8),ENSMUSG00000058600(Rpl30),ENSMUSG00000070428(Gm6570),ENSMUSG00000060209(Gm6109),ENSMUSG00000071671,ENSMUSG00000068599(Gm5481),ENSMUSG00000067125(Rpl30-ps6)" ENSG00000156482(RPL30) DRSC02087 EK -0.516873067 -1.346290054 0.465298829 -4.113185249 0.552455928 2.649441227 FBgn0039065 CG4449 http://flybase.net/reports/FBgn0039065.html protein_coding_gene "IPR029071=Ubiquitin-related domain, IPR022617=Rad60/SUMO-like domain" CG4449 16-Dec-15 2015_12 ENSG00000176953(NFATC2IP) viable FBgn0005429 l(1)EN14 lethal (1) from Eugene Nonautonomous 14 http://flybase.net/reports/FBgn0005429.html gene 16-Dec-15 2015_12 "lethal - all die before end of larval stage,recessive,some die during larval stage" embryonic/larval cuticle FBgn0002248 l(3)68Db lethal (3) 68Db http://flybase.net/reports/FBgn0002248.html gene "rose-gespleten region interval 9, rsg9, l(3)rsg9" 16-Dec-15 2015_12 lethal FBgn0031835 CG11319 http://flybase.net/reports/FBgn0031835.html protein_coding_gene "0008239=dipeptidyl-peptidase activity, 0008236=serine-type peptidase activity" 0006508=proteolysis 0016020=membrane "IPR002469=Dipeptidylpeptidase IV, N-terminal domain, IPR029058=Alpha/Beta hydrolase fold, IPR001375=Peptidase S9, prolyl oligopeptidase, catalytic domain" CG11319 16-Dec-15 2015_12 ENSDARG00000024744(dpp6b) "YHR028C(DAP2),YOR219C(STE13)" WBGene00001054(dpf-1) "ENSXETG00000006574(DPP6),ENSXETG00000009512(),ENSXETG00000000625(DPP10)" "ENSMUSG00000036815(Dpp10),ENSMUSG00000061576(Dpp6)" "ENSG00000175497(DPP10),ENSG00000130226(DPP6)" "viable,fertile" DRSC00942 K 0.472057899 -1.086596801 -0.357186086 -0.7162365 0.747019304 2.031985905 FBgn0053889 His4:CG33889 His4:CG33889 http://flybase.net/reports/FBgn0053889.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33889 "IPR009072=Histone-fold, IPR001951=Histone H4, IPR019809=Histone H4, conserved site" CG33889 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0036978 Toll-9 Toll-9 http://flybase.net/reports/FBgn0036978.html protein_coding_gene 0004888=transmembrane signaling receptor activity "0006967=positive regulation of antifungal peptide biosynthetic process, 0007165=signal transduction" 0016021=integral component of membrane "CG5528, Tl-5, dTLR9, TOLL 9, Dm Toll-9, CT17508, Tl-9, dToll9, toll receptor, Toll 9, Tak/Toll-like, toll" "IPR001611=Leucine-rich repeat, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR003591=Leucine-rich repeat, typical subtype" CG5528 16-Dec-15 2015_12 "ENSDARG00000043032(tlr1),ENSDARG00000037758(tlr2),ENSDARG00000040249(tlr18)" "ENSXETG00000018477(),ENSXETG00000001817(TLR2)" "ENSMUSG00000051498(Tlr6),ENSMUSG00000044827(Tlr1),ENSMUSG00000027995(Tlr2)" "ENSG00000174125(TLR1),ENSG00000174130(TLR6),ENSG00000174123(TLR10),ENSG00000137462" "lethal,short lived,developmental rate defective,partially lethal - majority die,some die during embryonic stage,viable,fertile" "leg,eye,embryonic/larval hemocyte" FBgn0036257 RhoGAP68F Rho GTPase activating protein at 68F http://flybase.net/reports/FBgn0036257.html protein_coding_gene "0017137=Rab GTPase binding, 0005096=GTPase activator activity" "0007370=ventral furrow formation, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0007266=Rho protein signal transduction, 0051497=negative regulation of stress fiber assembly, 0007480=imaginal disc-derived leg morphogenesis, 2001136=negative regulation of endocytic recycling" "0055037=recycling endosome, 0005769=early endosome" "RhoGAP68F, CG 6811, CG6811, RhoGAP" "IPR000198=Rho GTPase-activating protein domain, IPR001251=CRAL-TRIO lipid binding domain, IPR008936=Rho GTPase activation protein" CG6811 16-Dec-15 2015_12 ENSDARG00000024324(arhgap1) WBGene00012203(rga-1) ENSXETG00000001985(arhgap1) "ENSMUSG00000027247(Arhgap1),ENSMUSG00000078954(Arhgap8)" "ENSG00000175220(ARHGAP1),ENSG00000186654(PRR5)" "partially lethal - majority die,lethal,maternal effect,neuroanatomy defective,viable" "embryonic/first instar larval cuticle,maternal effect,ventral furrow,intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0031047 Rcd-1 Required for cell differentiation 1 ortholog http://flybase.net/reports/FBgn0031047.html protein_coding_gene "0017148=negative regulation of translation, 0006402=mRNA catabolic process" 0030014=CCR4-NOT complex "CG14213, Caf40, Required for cell differentiation 1, Drcd-1, CAF40" "IPR007216=Rcd1/Caf40, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold" CG14213 16-Dec-15 2015_12 ENSDARG00000033855(rqcd1) YNL288W(CAF40) WBGene00016139(C26E6.3) ENSXETG00000014984(rqcd1) ENSMUSG00000026174(Rqcd1) ENSG00000144580(RQCD1) "viable,visible,fertile" trichogen cell DRSC19569 I -1.710208536 2.943346331 -0.416651822 0.870365921 0.278662277 0.345434233 FBgn0053503 Cyp12d1-d Cyp12d1-d http://flybase.net/reports/FBgn0053503.html "FBgn0033576, FBgn0033577, FBgn0041339" protein_coding_gene "0020037=heme binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0005506=iron ion binding, 0030342=1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity" "0055114=oxidation-reduction process, 0046680=response to DDT, 0017085=response to insecticide" 0005739=mitochondrion "CT26082, cytochrome P450, CG18239, CG18240, Cyp12d2, Cyp12d1, 12D1, CG33503, 12d1, Cytochrome P450-12d1, CYP12D1, Cyp 12d1" "IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I, IPR001128=Cytochrome P450" CG33503 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" chemical resistant FBgn0027504 CG8878 http://flybase.net/reports/FBgn0027504.html protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity, 0004672=protein kinase activity" "0070374=positive regulation of ERK1 and ERK2 cascade, 0046579=positive regulation of Ras protein signal transduction, 0006468=protein phosphorylation" "BcDNA:LD23371, VRK" "IPR008271=Serine/threonine-protein kinase, active site, IPR000719=Protein kinase domain, IPR017441=Protein kinase, ATP binding site, IPR011009=Protein kinase-like domain" CG8878 16-Dec-15 2015_12 WBGene00017895(vrk-1) "fertile,viable,visible" "trichogen cell,mesothoracic tergum" DRSC05953 I -0.778155799 -1.884819853 -0.118305453 -0.648595662 -0.496772042 0.00251685 FBgn0031450 Hrs Hepatocyte growth factor regulated tyrosine kinase substrate http://flybase.net/reports/FBgn0031450.html "FBgn0013527, FBgn0041149" protein_coding_gene "0046872=metal ion binding, 0043130=ubiquitin binding" "0032509=endosome transport via multivesicular body sorting pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0033619=membrane protein proteolysis, 0031398=positive regulation of protein ubiquitination, 0016050=vesicle organization, 0016322=neuron remodeling, 0016079=synaptic vesicle exocytosis, 0008333=endosome to lysosome transport, 0007269=neurotransmitter secretion, 0008593=regulation of Notch signaling pathway, 0008293=torso signaling pathway, 0045752=positive regulation of Toll signaling pathway, 0045743=positive regulation of fibroblast growth factor receptor signaling pathway, 0006897=endocytosis, 0006886=intracellular protein transport, 1990182=exosomal secretion, 2000274=regulation of epithelial cell migration, open tracheal system, 0051726=regulation of cell cycle, 0016082=synaptic vesicle priming, 0001933=negative regulation of protein phosphorylation, 0016197=endosomal transport, 0007298=border follicle cell migration, 0006887=exocytosis" "0033565=ESCRT-0 complex, 0005737=cytoplasm, 0005768=endosome, 0005769=early endosome, 0005770=late endosome, 0008021=synaptic vesicle" "Hepatocyte growth factor regulated tyrosine kinase, HRS, hepatocyte growth factor-regulated tyrosine kinase substrate, l(2)23Ad, Hepatocyte growth factor-regulated tyrosine substrate, CG2903, Vps27, F[[1]]F[[0]] ATPase, HRS-2, l(2)23AB5, DmHRS, dHrs, Hepatocyte growth-factor-regulated substrate, Hepatocyte growth factor-regulated tyrosine kinase substrate, hrs, HGF-regulated tyrosine kinase substrate, vps27, l(2)23Ad(Hrs)" "IPR008942=ENTH/VHS, IPR018205=VHS subgroup, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR002014=VHS domain, IPR024641=Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain, IPR003903=Ubiquitin interacting motif, IPR011011=Zinc finger, FYVE/PHD-type, IPR017455=Zinc finger, FYVE-related, IPR017073=Ubiquitin binding protein, Hrs/VPS27, IPR000306=FYVE zinc finger" CG2903 16-Dec-15 2015_12 ENSDARG00000020960(LOC100331756) YNR006W(VPS27) WBGene00004101(hgrs-1) ENSXETG00000019701(hgs) ENSMUSG00000025793(Hgs) ENSG00000185359(HGS) "neuroanatomy defective,lethal,increased cell size,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,recessive,some die during larval stage,visible,partially lethal - majority die" "glial cell,eye disc,endosome,eye,somatic clone,photoreceptor cell,imaginal disc epithelial cell,late endosome | somatic clone,eye-antennal disc,border follicle cell,oocyte,vesicle,embryonic/larval garland cell,eye photoreceptor cell,wing margin,wing,wing margin bristle,chaeta,supernumerary,mesothoracic tergum" FBgn0034887 St1 Sulfotransferase 1 http://flybase.net/reports/FBgn0034887.html protein_coding_gene 0008146=sulfotransferase activity "0051923=sulfation, 0006805=xenobiotic metabolic process" 0005829=cytosol "CG5428, dmST1, st1" "IPR000863=Sulfotransferase domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG5428 16-Dec-15 2015_12 "ENSDARG00000053331(sult2st2),ENSDARG00000033170(sult2st1),ENSDARG00000028367(sult2st3),ENSDARG00000007769(zgc:153723),ENSDARG00000042919,ENSDARG00000040781(zgc:113317),ENSDARG00000042920(si:dkey-236e20.2),ENSDARG00000042923(sult3st2),ENSDARG00000009885(sult3st1),ENSDARG00000071495" WBGene00013748(ssu-1) "ENSXETG00000012821(BC061263.1),ENSXETG00000006064(TTpA004g18.1),ENSXETG00000019804(BC088870.1),ENSXETG00000010085(SULT2A1),ENSXETG00000014075(BC088888.1)" "ENSMUSG00000069668(Sult3a1),ENSMUSG00000003271(Sult2b1),ENSMUSG00000029273(Sult1d1),ENSMUSG00000023943(Sult1c1),ENSMUSG00000079135,ENSMUSG00000074375(Sult2a3),ENSMUSG00000029269(Sult1b1),ENSMUSG00000023122(Sult1c2),ENSMUSG00000078799,ENSMUSG00000074377(Sult2a4),ENSMUSG00000078798(Sult2a1),ENSMUSG00000029272(Sult1e1),ENSMUSG00000070810(Sult2a6)" "ENSG00000173597(SULT1B1),ENSG00000198075(SULT1C4),ENSG00000197165(SULT1A2),ENSG00000198203(SULT1C2),ENSG00000196502(SULT1A1),ENSG00000213599(SULT1A3),ENSG00000213648(SULT1A4),ENSG00000196228(SULT1C3),ENSG00000088002(SULT2B1),ENSG00000105398(SULT2A1)" "viable,visible" trichogen cell FBgn0004117 Tm2 Tropomyosin 2 http://flybase.net/reports/FBgn0004117.html "FBgn0002442, FBgn0003722, FBgn0003724, FBgn0026830" protein_coding_gene 0003779=actin binding 0007507=heart development 0005862=muscle thin filament tropomyosin "IP16005p, CG4843, dro Tm, Ifm-TmI, Tm2, Ifm(3)3, tropomyosin2, Tropomyosin-2, Tm1, TmI, tropomyosin-2, Tm127, l(3)nc99Eb, mTmI, Tn-H, lethal(3)nc99Eb, Tm, Tropomyosin I, tropomyosin, Tropomyosin, TM2, Ifm(3)5, DROTROPI1, TmII, tropomyosin 127, tropomyosin I" IPR000533=Tropomyosin CG4843 16-Dec-15 2015_12 "ENSDARG00000033683(tpma),ENSDARG00000068385(tpm2),ENSDARG00000013228,ENSDARG00000023963(tpm4),ENSDARG00000005162(tpm3),ENSDARG00000019128(zgc:63734)" WBGene00002978(lev-11) "ENSXETG00000009718(BC076711.1),ENSXETG00000008736(tpm4),ENSXETG00000009615(TPM2)" "ENSMUSG00000027940(Tpm3),ENSMUSG00000032366(Tpm1),ENSMUSG00000058126,ENSMUSG00000028464(Tpm2),ENSMUSG00000031799(Tpm4)" "ENSG00000143549(TPM3),ENSG00000167460(TPM4),ENSG00000198467(TPM2),ENSG00000140416(TPM1)" " adult stage , embryonic stage | late , pupal stage " " leg

, adult thorax

" "flightless,semidominant,viable,dominant,wild-type,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,flight defective,visible" "adult heart chamber,adult heart,myofibril,indirect flight muscle,embryonic/larval heart,trichogen cell" FBgn0038286 CG6966 http://flybase.net/reports/FBgn0038286.html FBgn0063758 protein_coding_gene 0004842=ubiquitin-protein transferase activity 0051438=regulation of ubiquitin-protein transferase activity BcDNA:AT05246 "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat" CG6966 16-Dec-15 2015_12 "ENSDARG00000067966,ENSDARG00000013375" WBGene00001411(fem-1) ENSXETG00000018747(FEM1C) "ENSMUSG00000033319(Fem1c),ENSMUSG00000043683(Fem1a),ENSMUSG00000078157(4931440F15Rik)" "ENSG00000145780(FEM1C),ENSG00000141965(FEM1A)" viable FBgn0039085 CG10170 http://flybase.net/reports/FBgn0039085.html protein_coding_gene 0003851=2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 0008152=metabolic process IPR002213=UDP-glucuronosyl/UDP-glucosyltransferase CG10170 16-Dec-15 2015_12 "ENSDARG00000032862(ugt5g1),ENSDARG00000058845,ENSDARG00000011537(ugt2a5),ENSDARG00000011197,ENSDARG00000058841,ENSDARG00000051940(zgc:112490),ENSDARG00000043901,ENSDARG00000039501(ugt2a6),ENSDARG00000061672(LOC100332635),ENSDARG00000058048(ugt5e1),ENSDARG00000002394,ENSDARG00000013580,ENSDARG00000057612(ugt5b4),ENSDARG00000006372(ugt5c2),ENSDARG00000061439(ugt5c3),ENSDARG00000061444(LOC100004580),ENSDARG00000058849,ENSDARG00000057613,ENSDARG00000051806(LOC100330216),ENSDARG00000051805(LOC100330141),ENSDARG00000016479(zgc:153634),ENSDARG00000006220(LOC100192381),ENSDARG00000055960,ENSDARG00000037455(zgc:136652),ENSDARG00000037445" "WBGene00019515(ugt-19),WBGene00007455(ugt-22),WBGene00019516(ugt-20),WBGene00007885(ugt-21),WBGene00007650(ugt-23),WBGene00016762(ugt-24),WBGene00015692(ugt-25),WBGene00008097(ugt-15),WBGene00013900(ugt-18),WBGene00013901(ugt-16),WBGene00018543(ugt-32),WBGene00007422(ugt-17),WBGene00021709(ugt-29),WBGene00015694(ugt-27),WBGene00015695(ugt-26),WBGene00008486(ugt-44),WBGene00011340(ugt-30),WBGene00021464(ugt-31),WBGene00015693(ugt-28),WBGene00016013(C23G10.6),WBGene00008485(ugt-43),WBGene00021372(ugt-45),WBGene00019379(K04A8.10),WBGene00019181(H10D18.6)" "ENSG00000109181(UGT2B10),ENSG00000213759(UGT2B11),ENSG00000135226(UGT2B28),ENSG00000171234(UGT2B7),ENSG00000156096(UGT2B4),ENSG00000197592,ENSG00000196620(UGT2B15),ENSG00000197888(UGT2B17),ENSG00000173610(UGT2A2),ENSG00000135220(UGT2A3),ENSG00000167165(UGT1A6)" viable DRSC26386 K -0.744775119 -0.592392884 -0.117209462 -0.296797189 3.832767986 0.866394865 FBgn0017590 klg klingon http://flybase.net/reports/FBgn0017590.html "FBgn0011803, FBgn0015947" protein_coding_gene "0008355=olfactory learning, 0007611=learning or memory, 0045466=R7 cell differentiation, 0007465=R7 cell fate commitment, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007616=long-term memory, 0007615=anesthesia-resistant memory, 0048149=behavioral response to ethanol" 0019897=extrinsic component of plasma membrane "Klg, CG6669, l(3)rN712, CT20712, h214, Klingon, ruslan" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain" CG6669 16-Dec-15 2015_12 WBGene00006942(wrk-1) " pupal stage , embryonic stage | stage >=12 , larval stage | third instar " " photoreceptor cell R8

, neuron

, embryonic peripheral nervous system

, eye disc | restricted

, photoreceptor cell R7

, lamina anlage | restricted

, embryonic central nervous system | restricted

, morphogenetic furrow | posterior to

" "memory defective,recessive,chemical sensitive,lethal,lethal - all die before end of larval stage,some die during larval stage,long lived,viable" "photoreceptor cell,photoreceptor cell R7,ommatidium" DRSC13591 IE -1.639676546 -0.363293613 -2.893383398 -0.563477559 -0.751581179 -0.198196403 FBgn0038047 CG5245 http://flybase.net/reports/FBgn0038047.html FBgn0061830 protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" anon-WO0118547.611 "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG5245 16-Dec-15 2015_12 "ENSDARG00000058507(LOC100334938),ENSDARG00000043302(zgc:112958),ENSDARG00000069562,ENSDARG00000071790(zgc:171318),ENSDARG00000071785(LOC100149943),ENSDARG00000051985(zgc:113389),ENSDARG00000071097,ENSDARG00000058827,ENSDARG00000003102(zgc:101130),ENSDARG00000043126(blf),ENSDARG00000067502,ENSDARG00000039716(zgc:113102),ENSDARG00000035221(zgc:110249)" YPR186C(PZF1) WBGene00021931(Y55F3AM.14) "viable,fertile" FBgn0000810 fs(1)K10 female sterile (1) K10 http://flybase.net/reports/FBgn0000810.html FBgn0029607 protein_coding_gene 0003677=DNA binding "0030707=ovarian follicle cell development, 0019094=pole plasm mRNA localization, 0017148=negative regulation of translation, 0008298=intracellular mRNA localization, 0048477=oogenesis, 0008104=protein localization, 0007310=oocyte dorsal/ventral axis specification, 0009953=dorsal/ventral pattern formation" 0005634=nucleus "K-10, fs(1)M9, k10, f(s)K10, K10, fs(1)k10, CG3218, EG:30B8.5" CG3218 16-Dec-15 2015_12 " embryonic stage -- adult stage , embryonic stage | early , embryonic stage | female , oogenesis stage && adult stage | female , adult stage && oogenesis stage | female , adult stage | female , embryonic stage | stage 1-13 , adult stage && oogenesis stage " " oocyte

, germarium

, oocyte

{ v BicDr } , organism

, ovary

, oocyte

{ v BicDR26 } , cystoblast

" adult stage && oogenesis stage | stage S8-9 oocyte

"female sterile,wild-type,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,germline clone,non-rescuable maternal effect" "egg,chorion,maternal effect,chorion | germline clone | maternal effect,embryo,dorsal appendage,follicle cell,oocyte,egg chamber,ventral,filzkorper,epidermis,ectopic" FBgn0002872 mu2 mutator 2 http://flybase.net/reports/FBgn0002872.html protein_coding_gene 0006302=double-strand break repair "cDNA D, MU2, CG1960, MDC1, mu-2, mutator[2]" IPR001357=BRCT domain CG1960 16-Dec-15 2015_12 ENSMUSG00000061607(Mdc1) " embryonic stage , adult stage | female && oogenesis stage | stage S5-6 , adult stage && oogenesis stage | stage >=S8 , adult stage && oogenesis stage , larval stage , embryonic stage -- adult stage , embryonic stage | early " " embryonic central nervous system

, oocyte | posterior

, oocyte | anterior

, germarium

, larval brain

,

ubiquitous , eye disc

, morphogenetic furrow

, oocyte

, imaginal disc

" "viable,fertile,wild-type,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259937 Nop60B Nucleolar protein at 60B http://flybase.net/reports/FBgn0259937.html "FBgn0023184, FBgn0022178, FBgn0083122" protein_coding_gene "0003723=RNA binding, 0009982=pseudouridine synthase activity, 0004730=pseudouridylate synthase activity" "0006364=rRNA processing, 0007281=germ cell development, 0009267=cellular response to starvation, 0001522=pseudouridine synthesis, 0035220=wing disc development, 0022008=neurogenesis, 0042254=ribosome biogenesis" "0005634=nucleus, 0005730=nucleolus" "MFL/Nop60B, Uhg6, nop60B, mfl, l(2)k05318, CG3333, FBgn0023184, minifly, dUhg-like 6, Nop60b, CG333, Nop60, Minifly, dUhg6" "IPR002478=PUA domain, IPR012960=Dyskerin-like, IPR002501=Pseudouridine synthase II, IPR015947=PUA-like domain, IPR020103=Pseudouridine synthase, catalytic domain, IPR004802=tRNA pseudouridine synthase B family" CG3333 16-Dec-15 2015_12 ENSDARG00000016484(dkc1) YLR175W(CBF5) WBGene00010478(K01G5.5) ENSXETG00000023828(TRUB1) ENSMUSG00000031403(Dkc1) ENSG00000130826(DKC1) " embryonic stage | stage 4-14 , adult stage && oogenesis stage , embryonic stage , embryonic stage&&larval stage , embryonic stage -- adult stage , oogenesis stage , embryonic stage | 0-4 hr , adult stage | female , oogenesis stage | stage >=S3 && adult stage | female , embryonic stage | 0-6 hr , embryonic stage | 0-4hr " "

ubiquitous , nurse cell

, ovary

ubiquitous , oocyte

, ovary

" " adult stage && oogenesis stage , oogenesis stage , embryonic stage " " germarium

,

ubiquitous , follicle cell

, ovary

" FBgn0264307 orb2 http://flybase.net/reports/FBgn0264307.html "FBgn0262573, FBgn0035938, FBgn0044649, FBgn0264304" protein_coding_gene "0003730=mRNA 3'-UTR binding, 0000900=translation repressor activity, nucleic acid binding, 0003723=RNA binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0007616=long-term memory, 0007141=male meiosis I, 0007283=spermatogenesis, 0008049=male courtship behavior, 0007288=sperm axoneme assembly, 0008356=asymmetric cell division, 0017148=negative regulation of translation, 0007291=sperm individualization" "0048471=perinuclear region of cytoplasm, 0044297=cell body, 0005829=cytosol, 0005737=cytoplasm, 0045202=synapse, 0043679=axon terminus, 0044292=dendrite terminus" "cg5735, anon-WO0140519.222, CG43782, CG5735, CG43113, orb2, Orb2" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG43782 16-Dec-15 2015_12 "ENSDARG00000056691,ENSDARG00000060495(wu:fb09b10),ENSDARG00000052604,ENSDARG00000060103(cpeb3)" WBGene00000770(cpb-1) "ENSXETG00000012190(cpeb3),ENSXETG00000020324(CPEB2),ENSXETG00000012731(CPEB4)" "ENSMUSG00000039652(Cpeb3),ENSMUSG00000020300(Cpeb4),ENSMUSG00000039782(Cpeb2)" "ENSG00000107864(CPEB3),ENSG00000113742(CPEB4),ENSG00000137449(CPEB2)" FBgn0027945 ppl pumpless http://flybase.net/reports/FBgn0027945.html FBgn0013569 protein_coding_gene "0006546=glycine catabolic process, 0019464=glycine decarboxylation via glycine cleavage system, 0035220=wing disc development" "0005739=mitochondrion, 0005960=glycine cleavage complex" "l(3)78Cb, l(3)00217, CG7758" "IPR003016=2-oxo acid dehydrogenase, lipoyl-binding site, IPR000089=Biotin/lipoyl attachment, IPR017453=Glycine cleavage system H-protein, subgroup, IPR011053=Single hybrid motif, IPR002930=Glycine cleavage system H-protein" CG7758 16-Dec-15 2015_12 "ENSDARG00000042096(gcshb),ENSDARG00000016717(gcsha)" YAL044C(GCV3) "WBGene00008354(D1025.2),WBGene00009918(F52A8.5)" ENSXETG00000000187(gcsh) ENSMUSG00000034424(Gcsh) ENSG00000140905(GCSH) " embryonic stage&&larval stage , embryonic stage | stage 15-17 " " embryonic/larval fat body

, embryonic fat body

, larval fat body

" "lethal,recessive,feeding behavior defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,viable,visible" "embryonic/larval pharynx,embryonic/larval digestive system,trichogen cell" FBgn0036698 CG7724 http://flybase.net/reports/FBgn0036698.html protein_coding_gene "0016614=oxidoreductase activity, acting on CH-OH group of donors, 0008460=dTDP-glucose 4,6-dehydratase activity, 0003854=3-beta-hydroxy-delta5-steroid dehydrogenase activity" "0006694=steroid biosynthetic process, 0055114=oxidation-reduction process, 0009225=nucleotide-sugar metabolic process" "IPR016040=NAD(P)-binding domain, IPR002225=3-beta hydroxysteroid dehydrogenase/isomerase, IPR005888=dTDP-glucose 4,6-dehydratase" CG7724 16-Dec-15 2015_12 "ENSDARG00000019747(hsd3b1),ENSDARG00000069926(si:rp71-68n21.10),ENSDARG00000067750,ENSDARG00000036966(hsd3b7)" YGL001C(ERG26) "ENSXETG00000001913(HSD3B7),ENSXETG00000004490(),ENSXETG00000018079()" "ENSMUSG00000027871(Hsd3b1),ENSMUSG00000027869(Hsd3b6),ENSMUSG00000063730(Hsd3b2),ENSMUSG00000062410(Hsd3b3),ENSMUSG00000056351(Hsd3b4),ENSMUSG00000074380(Gm10681),ENSMUSG00000038092(Hsd3b5),ENSMUSG00000042289(Hsd3b7)" "ENSG00000203859(HSD3B2),ENSG00000203857(HSD3B1),ENSG00000099377(HSD3B7)" lethal FBgn0052706 CG32706 http://flybase.net/reports/FBgn0052706.html protein_coding_gene "0003676=nucleic acid binding, 0000166=nucleotide binding" 0042742=defense response to bacterium "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG32706 16-Dec-15 2015_12 ENSDARG00000043666(zgc:109995) YNR054C(ESF2) WBGene00019005(F57B10.8) ENSXETG00000005684(ABT1) ENSMUSG00000036376(Abt1) ENSG00000146109(ABT1) FBgn0039862 kek6 kek6 http://flybase.net/reports/FBgn0039862.html protein_coding_gene "0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0046331=lateral inhibition" 0005887=integral component of plasma membrane "kekkon-like, CG1804" "IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003591=Leucine-rich repeat, typical subtype, IPR000483=Cysteine-rich flanking region, C-terminal, IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG1804 16-Dec-15 2015_12 "ENSDARG00000007856,ENSDARG00000055578(rtn4rl1),ENSDARG00000052012(rtn4rl2a),ENSDARG00000037495(rtn4rl2b),ENSDARG00000025697(rtn4r)" "ENSXETG00000016016(ELFN2),ENSXETG00000022994()" "ENSMUSG00000048988(Elfn1),ENSMUSG00000043460(Elfn2)" "ENSG00000173621(LRFN4),ENSG00000156564(LRFN2),ENSG00000126243(LRFN3),ENSG00000165379(LRFN5),ENSG00000128011(LRFN1)" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0026192 par-6 par-6 http://flybase.net/reports/FBgn0026192.html protein_coding_gene 0005515=protein binding "0045196=establishment or maintenance of neuroblast polarity, 0007416=synapse assembly, 0051491=positive regulation of filopodium assembly, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0060446=branching involved in open tracheal system development, 0008360=regulation of cell shape, 0007309=oocyte axis specification, 0010592=positive regulation of lamellipodium assembly, 0006469=negative regulation of protein kinase activity, 0006909=phagocytosis, 0007298=border follicle cell migration, 0045176=apical protein localization, 0001738=morphogenesis of a polarized epithelium, 0045200=establishment of neuroblast polarity, 0045186=zonula adherens assembly, 0007155=cell adhesion, 0007293=germarium-derived egg chamber formation, 0060429=epithelium development, 0055059=asymmetric neuroblast division, 0045197=establishment or maintenance of epithelial cell apical/basal polarity" "0005938=cell cortex, 0016324=apical plasma membrane, 0035003=subapical complex, 0043195=terminal bouton, 0097482=muscle cell postsynaptic density, 0045179=apical cortex" "dPar-6, PAR-6, dmPar-6, Dm-Par6, CG5884, DmPar6, dPAR-6, Dm-Par-6, Par-6, par6, DmPAR-6, Par, PAR6, DPar6, DPar-6, Dmpar6, par, DmPar-6, Par6" "IPR000270=PB1 domain, IPR001478=PDZ domain" CG5884 16-Dec-15 2015_12 "ENSDARG00000003865(pard6b),ENSDARG00000036090(pard6gb),ENSDARG00000031876(pard6ga),ENSDARG00000069378(pard6a)" WBGene00003921(par-6) "ENSXETG00000012298(pard6b),ENSXETG00000014825(pard6g)" "ENSMUSG00000056214(Pard6g),ENSMUSG00000044641(Pard6b)" "ENSG00000124171(PARD6B),ENSG00000178184(PARD6G),ENSG00000102981(PARD6A)" pupal stage photoreceptor cell stalk | apical

"lethal,recessive,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,visible" "border follicle cell,border follicle cell & filopodium | ectopicslbo.2.6, upd.PU,terminal tracheal cell,somatic clone,embryonic/larval cuticle,embryonic head,epithelial cell,germline clone,embryonic neuroblast,embryonic/first instar larval cuticle,egg chamber,oocyte,follicle cell,bouton,trichogen cell,mesothoracic tergum,epithelium,female germline cyst" FBgn0001215 Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE http://flybase.net/reports/FBgn0001215.html "FBgn0003056, FBgn0014945" protein_coding_gene "0000166=nucleotide binding, 0003729=mRNA binding, 0048027=mRNA 5'-UTR binding, 0043565=sequence-specific DNA binding" "0045727=positive regulation of translation, 0033119=negative regulation of RNA splicing, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0036099=female germ-line stem cell maintenance, 0048477=oogenesis, 0001745=compound eye morphogenesis" "0030529=ribonucleoprotein complex, 0005634=nucleus, 0005703=polytene chromosome puff" "p9, Hrb1, hnRNA-binding protein 1, CG9983, HDP(P9), HRB98DE, hrb98DE, Hrb98 de, Hrp38, hnRNP A2/B1, HRB98DE/hrp38, Hrb98DE/Hrp38, hrb98 de, E7Delta6, anon-E7Delta6, s, Pen9, hrp38" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR000504=RNA recognition motif domain" CG9983 16-Dec-15 2015_12 "ENSDARG00000036675(hnrnpa1),ENSDARG00000059351(hnrnpa3)" WBGene00001999(hrp-1) "ENSXETG00000001806(HNRNPA3),ENSXETG00000021277(hnrpa1),ENSXETG00000012170(hnrpa2b1)" "ENSMUSG00000046434(Hnrnpa1),ENSMUSG00000059005(Hnrnpa3),ENSMUSG00000004980(Hnrnpa2b1),ENSMUSG00000060989,ENSMUSG00000059179" "ENSG00000135486(HNRNPA1),ENSG00000139675(HNRNPA1L2),ENSG00000170144(HNRNPA3),ENSG00000122566(HNRNPA2B1),ENSG00000215492" " pupal stage , oogenesis stage && adult stage | female , embryonic stage | early " ovary

"viable,lethal,fertile,visible,body color defective,planar polarity defective,female semi-sterile,partially lethal - majority die,some die during larval stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,oocyte,egg chamber,anterior,lateral,female germline stem cell" FBgn0028684 Rpt5 Regulatory particle triple-A ATPase 5 http://flybase.net/reports/FBgn0028684.html "FBgn0010835, FBgn0026321, FBgn0027925, FBgn0045868, FBgn0045870, FBgn0045946" protein_coding_gene "0004175=endopeptidase activity, 0005524=ATP binding, 0016887=ATPase activity, 0016787=hydrolase activity" 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process "0008540=proteasome regulatory particle, base subcomplex, 0005838=proteasome regulatory particle, 0005737=cytoplasm" "BcDNA.GH12068, Dm_Rpt5b, Tbp-1, anon-WO0153538.9, tbp-1, Tbp1, Proteasome 26S regulatory subunit 6A, p50, S6', anon-WO0153538.8, Dm_Rpt5a, DmTBP-1, CG10370, BcDNA:GH12068, Pros26S-RS6A, l(3)04210, dRpt5, anon-WO0153538.10, Pros26S, Tat-binding protein-1, Rpt5, TBP-1" "IPR003593=AAA+ ATPase domain, IPR003960=ATPase, AAA-type, conserved site, IPR005937=26S proteasome subunit P45, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR003959=ATPase, AAA-type, core" CG10370 16-Dec-15 2015_12 ENSDARG00000007141(psmc3) YOR117W(RPT5) WBGene00004505(rpt-5) ENSXETG00000007916(psmc3) ENSMUSG00000002102(Psmc3) ENSG00000165916(PSMC3) "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" DRSC16842 IEK -1.856344141 -4.440338936 -3.623261681 -5.72668481 -0.616425886 -3.092182833 FBgn0036811 MED11 Mediator complex subunit 11 http://flybase.net/reports/FBgn0036811.html "FBgn0045879, FBgn0063287" protein_coding_gene "0003713=transcription coactivator activity, 0001104=RNA polymerase II transcription cofactor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0007406=negative regulation of neuroblast proliferation, 0048813=dendrite morphogenesis" "0005634=nucleus, 0016592=mediator complex" "CG6884, RNA Poll II transcription mediator, Med11, Med21, med11, anon-WO0153538.71, dMED21, BcDNA:GH01072" "IPR019404=Mediator complex, subunit Med11" CG6884 16-Dec-15 2015_12 ENSDARG00000069337(med11) WBGene00007015(mdt-11) ENSXETG00000006384(BC064722.1) ENSMUSG00000018923(Med11) ENSG00000161920(MED11) lethal DRSC23091 K 2.643702718 2.254138702 FBgn0053901 His4:CG33901 His4:CG33901 http://flybase.net/reports/FBgn0053901.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0006334=nucleosome assembly, 0006333=chromatin assembly or disassembly" "0000786=nucleosome, 0005634=nucleus" CG33901 "IPR019809=Histone H4, conserved site, IPR009072=Histone-fold, IPR001951=Histone H4" CG33901 16-Dec-15 2015_12 "ENSDARG00000068057,ENSDARG00000068924,ENSDARG00000067933,ENSDARG00000060844,ENSDARG00000063053,ENSDARG00000068930,ENSDARG00000060819,ENSDARG00000060857,ENSDARG00000067907,ENSDARG00000070279,ENSDARG00000070257,ENSDARG00000068060,ENSDARG00000067941,ENSDARG00000063057,ENSDARG00000060859,ENSDARG00000070253,ENSDARG00000068040,ENSDARG00000070260,ENSDARG00000061510,ENSDARG00000067938,ENSDARG00000061547(zgc:153409),ENSDARG00000060850,ENSDARG00000070290,ENSDARG00000068047,ENSDARG00000070283,ENSDARG00000067737,ENSDARG00000061507,ENSDARG00000059748" "YNL030W(HHF2),YBR009C(HHF1)" WBGene00001884(his-10) "ENSXETG00000026067(TGas006m08.1),ENSXETG00000027976(TGas006m08.1),ENSXETG00000024970(TGas006m08.1),ENSXETG00000026510(TGas006m08.1),ENSXETG00000026733(TGas006m08.1),ENSXETG00000027178(TGas006m08.1),ENSXETG00000026679(TGas006m08.1),ENSXETG00000027234(TGas006m08.1),ENSXETG00000025756(TGas006m08.1),ENSXETG00000025961(TGas006m08.1),ENSXETG00000027169(TGas006m08.1),ENSXETG00000026965(TGas006m08.1),ENSXETG00000026738(TGas006m08.1),ENSXETG00000027964(TGas006m08.1),ENSXETG00000024977(TGas006m08.1),ENSXETG00000027197(TGas006m08.1),ENSXETG00000020498(TGas006m08.1),ENSXETG00000025931(TGas006m08.1),ENSXETG00000026966(TGas006m08.1),ENSXETG00000027140(TGas006m08.1),ENSXETG00000027181(TGas006m08.1),ENSXETG00000027503(TGas006m08.1),ENSXETG00000026076(TGas006m08.1),ENSXETG00000026073(TGas006m08.1),ENSXETG00000027200(TGas006m08.1),ENSXETG00000026728(TGas006m08.1),ENSXETG00000025390(TGas006m08.1),ENSXETG00000027166(TGas006m08.1),ENSXETG00000026467(TGas006m08.1),ENSXETG00000000626(TGas006m08.1),ENSXETG00000024251(TGas006m08.1),ENSXETG00000027164(TGas006m08.1),ENSXETG00000026407(TGas006m08.1),ENSXETG00000026735(TGas006m08.1),ENSXETG00000027175(TGas006m08.1),ENSXETG00000024981(TGas006m08.1),ENSXETG00000027514(TGas006m08.1),ENSXETG00000026668(TGas006m08.1),ENSXETG00000026305(TGas006m08.1),ENSXETG00000027579(TGas006m08.1),ENSXETG00000025686(TGas006m08.1),ENSXETG00000027966(TGas006m08.1),ENSXETG00000025555(TGas006m08.1),ENSXETG00000027187(TGas006m08.1),ENSXETG00000028012(TGas006m08.1),ENSXETG00000027129(TGas006m08.1),ENSXETG00000024984(TGas006m08.1),ENSXETG00000025353(TGas006m08.1),ENSXETG00000026118(TGas006m08.1),ENSXETG00000025396(TGas006m08.1),ENSXETG00000027133(TGas006m08.1)" "ENSMUSG00000069274(Hist1h4f),ENSMUSG00000069305(Hist1h4m),ENSMUSG00000060678(Hist1h4c),ENSMUSG00000069266(Hist1h4b),ENSMUSG00000064288(Hist1h4k),ENSMUSG00000061482(Hist1h4d),ENSMUSG00000069306(Gm11275),ENSMUSG00000068851(Hist2h4),ENSMUSG00000067455(Hist4h4),ENSMUSG00000060832(Hist1h4j),ENSMUSG00000060093(Hist1h4a),ENSMUSG00000060981(Hist1h4h),ENSMUSG00000060639(Hist1h4i)" "ENSG00000182217,ENSG00000183941,ENSG00000198518(HIST1H4E),ENSG00000198339(HIST1H4I),ENSG00000198558(HIST1H4L),ENSG00000188987(HIST1H4D),ENSG00000198327(HIST1H4F),ENSG00000124529(HIST1H4B),ENSG00000197914(HIST1H4K),ENSG00000158406(HIST1H4H),ENSG00000197837(HIST4H4),ENSG00000197061(HIST1H4C),ENSG00000197238(HIST1H4J)" FBgn0053835 His2A:CG33835 His2A:CG33835 http://flybase.net/reports/FBgn0053835.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33835 "IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A, IPR009072=Histone-fold" CG33835 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0035416 gry gryzun http://flybase.net/reports/FBgn0035416.html protein_coding_gene "0007616=long-term memory, 0046907=intracellular transport, 0007611=learning or memory, 0008355=olfactory learning" "0005737=cytoplasm, 0005794=Golgi apparatus" "Gryzun, CG17569" "IPR021773=Foie gras liver health family 1, IPR025876=Trafficking protein particle complex subunit 11, C-terminal" CG17569 16-Dec-15 2015_12 ENSDARG00000004726(foigr) WBGene00015173(B0412.3) ENSMUSG00000038102(D030016E14Rik) ENSG00000168538(C4orf41) "memory defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053817 His2A:CG33817 His2A:CG33817 http://flybase.net/reports/FBgn0053817.html protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33817 "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A" CG33817 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0022800 Cad96Ca Cadherin 96Ca http://flybase.net/reports/FBgn0022800.html FBgn0039289 protein_coding_gene "0005509=calcium ion binding, 0005524=ATP binding, 0004714=transmembrane receptor protein tyrosine kinase activity, 0004672=protein kinase activity, 0004713=protein tyrosine kinase activity" "0016339=calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, 0006468=protein phosphorylation, 0042060=wound healing, 0045792=negative regulation of cell size, 0007030=Golgi organization, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0090303=positive regulation of wound healing" "0005887=integral component of plasma membrane, 0016020=membrane, 0045177=apical part of cell" "Stitcher, CG10239, cad96C, Dm Cad96Ca, Cad96C, DCad96Ca, FGFR1-like, CT28779, cad96Ca, stit, HD-14, CG10244, DmHD-14, stitcher, Cad96Ca" "IPR002126=Cadherin, IPR017441=Protein kinase, ATP binding site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR008266=Tyrosine-protein kinase, active site, IPR015919=Cadherin-like" CG10244 16-Dec-15 2015_12 YJL187C(SWE1) "lethal - all die during pupal stage,lethal - all die during embryonic stage,wound healing defective,lethal - all die before end of pupal stage,some die during pupal stage,viable" DRSC16693 K -0.161515465 -0.354177669 0.754090978 0.232806314 0.027884024 -1.517751387 FBgn0036538 CG15715 http://flybase.net/reports/FBgn0036538.html FBgn0047138 protein_coding_gene BcDNA:RE26825 "IPR026939=At2g23090-like, IPR007513=Uncharacterised protein family SERF, IPR015880=Zinc finger, C2H2-like" CG15715 16-Dec-15 2015_12 "ENSDARG00000056307(zgc:92624),ENSDARG00000035678(zgc:91910)" "WBGene00019609(K10B3.1),WBGene00007223(C01F6.9)" "ENSXETG00000006633(),ENSXETG00000027722(TNeu080o10.1)" "ENSMUSG00000062397(Zfp706),ENSMUSG00000067015(Gm10193)" ENSG00000120963(ZNF706) "viable,fertile" DRSC25332 K 0.351683277 0.353118799 -0.166410811 0.315967154 -1.708995587 0.556850082 FBgn0001138 grn grain http://flybase.net/reports/FBgn0001138.html "FBgn0004213, FBgn0015228, FBgn0019991" protein_coding_gene "0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0008270=zinc ion binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0008045=motor neuron axon guidance, 0009888=tissue development, 0009887=organ morphogenesis" 0005634=nucleus "Gata-c, l(3)84Fa, Grn, lethal(3)84Fa, GRAIN, dGATAc, CG9656, CG9656-PA, dGATA-2, GATAc, dGatac, Gata2, GATA-factor-c, gra" "IPR000679=Zinc finger, GATA-type, IPR013088=Zinc finger, NHR/GATA-type" CG9656 16-Dec-15 2015_12 "ENSDARG00000059327(gata2a),ENSDARG00000070026,ENSDARG00000016526(gata3),ENSDARG00000069357,ENSDARG00000009094(gata2b)" "ENSXETG00000016171(GATA2),ENSXETG00000025398(gata3)" "ENSMUSG00000015619(Gata3),ENSMUSG00000015053(Gata2)" "ENSG00000107485(GATA3),ENSG00000179348(GATA2)" " embryonic stage | stage >=12 , embryonic stage | stage >=5 , embryonic stage | stage >=11 , embryonic stage | stage 5 , embryonic stage | cellular blastoderm | late " " embryonic brain

, embryonic central nervous system

segmentally repeated , optic lobe

, organism

, embryonic central nervous system

, anterior midgut proper primordium

, organism | ventral

, labral segment

anterior , embryonic head | precursor & dorsal

, organism | 40-60% egg length & dorsal

,

15-25% egg length <&> dorsal , posterior midgut proper primordium

, embryonic/larval posterior spiracle

" "lethal,recessive,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" "cephalopharyngeal skeleton,filzkorper,leg,proximal,somatic clone,tibia,femur,stigmatophore,intersegmental nerve,lateral process,dorsal bridge,aCC neuron,RP2 motor neuron,denticle belt,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic telson" DRSC16961 E 0.207795218 0.896968844 1.541151876 -0.512022324 -1.496466098 0.13437874 FBgn0031114 cactin cactin http://flybase.net/reports/FBgn0031114.html protein_coding_gene 0044822=poly(A) RNA binding "0048812=neuron projection morphogenesis, 0006952=defense response, 0009950=dorsal/ventral axis specification, 0000398=mRNA splicing, via spliceosome, 0007165=signal transduction, 0022008=neurogenesis" 0071013=catalytic step 2 spliceosome "Cactin, CG1676" "IPR019134=Cactin, C-terminal, IPR018816=Cactin, central domain" CG1676 16-Dec-15 2015_12 ENSDARG00000059866(LOC100334286) WBGene00012230(cacn-1) ENSXETG00000022106(C19orf29) ENSMUSG00000034889(2510012J08Rik) ENSG00000105298(C19orf29) "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC20576 I 0.369370613 1.935209779 0.261236265 0.572818458 -0.63956845 -0.437344408 FBgn0033966 CG12856 http://flybase.net/reports/FBgn0033966.html protein_coding_gene CT31996 16-Dec-15 2015_12 DRSC23818 K -0.617822516 -0.359490066 -0.033416717 0.191489721 -1.667674287 -0.631814433 FBgn0028867 CR15280 http://flybase.net/reports/FBgn0028867.html FBgn0032550 pseudogene_attribute "SPH204, BG:DS06874.4, CG15280" CR15280 16-Dec-15 2015_12 DRSC01953 I 0.680895165 1.583823029 1.388842966 0.196500047 -1.28410413 -0.551679286 FBgn0034878 pita pita http://flybase.net/reports/FBgn0034878.html FBgn0015545 protein_coding_gene "0005515=protein binding, 0043035=chromatin insulator sequence binding, 0008270=zinc ion binding, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003682=chromatin binding" "0006260=DNA replication, 0007067=mitotic nuclear division, 0006355=regulation of transcription, DNA-templated, 0042023=DNA endoreduplication, 0060968=regulation of gene silencing" "0005634=nucleus, 0005700=polytene chromosome" "spdk, spotted dick, CG3941, PITA, Pita" "IPR012934=Zinc finger, AD-type, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG3941 16-Dec-15 2015_12 WBGene00009448(zfp-2) "lethal,recessive,mitotic cell cycle defective,germline clone,maternal effect,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,female semi-sterile,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval digestive system,melanotic mass,mitotic metaphasebw5),condensed nuclear chromosomebw5),spindlebw5),mitotic anaphasebw5),egg chamber,germline clone,follicle cell,nurse cell & nucleus | germ-line clone,nurse cell,nurse cell & polytene chromosome | germ-line clone,mitotic metaphase,condensed nuclear chromosome,spindle,mitotic anaphase,mitotic G2 phase,embryonic/larval salivary gland,imaginal disc,embryonic/larval tracheal system" DRSC04435 EK 0.049888981 -0.897190165 -0.84732436 -3.633452113 0.470685556 1.942202897 FBgn0015296 Shc SHC-adaptor protein http://flybase.net/reports/FBgn0015296.html FBgn0035990 protein_coding_gene "0007173=epidermal growth factor receptor signaling pathway, 0035011=melanotic encapsulation of foreign target, 0007426=tracheal outgrowth, open tracheal system, 0038202=TORC1 signaling, 0008293=torso signaling pathway" "shc, CG3715, DSHC, dshc, dShc, D-Shc" "IPR000980=SH2 domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR006020=PTB/PI domain, IPR006019=Phosphotyrosine interaction domain, Shc-like" CG3715 16-Dec-15 2015_12 "ENSDARG00000057731(LOC100332111),ENSDARG00000062080(si:dkey-94n12.3)" WBGene00018788(shc-1) "ENSXETG00000006562(SHC2),ENSXETG00000015404(SHC1),ENSXETG00000008782(SHC4)" "ENSMUSG00000020312(Shc2),ENSMUSG00000042626(Shc1),ENSMUSG00000021448(Shc3),ENSMUSG00000035109(Shc4)" "ENSG00000185634(SHC4),ENSG00000160691(SHC1),ENSG00000148082(SHC3),ENSG00000129946(SHC2)" "partially lethal - majority die,recessive,female sterile,lethal,maternal effect,planar polarity defective,male sterile,visible,germline clone,terminal phenotype,viable,immune response defective" "mesoderm,germline clone,embryonic/first instar larval cuticle,maternal effect,denticle belt,filzkorper,embryonic abdominal segment 8,Malpighian tubule,cephalopharyngeal skeleton,extended germ band embryo,egg,eye,wing,ovary,ommatidium,anterior,eye photoreceptor cell,wing vein L4,distal,dorsal appendage,chorion | maternal effect,dorsal air sac primordium,somatic clone,border follicle cell,embryo" DRSC11284 IE -0.269129314 -1.608022249 -1.609210849 -0.254884096 -1.13792851 -1.484316015 FBgn0050010 CG30010 http://flybase.net/reports/FBgn0050010.html FBgn0062867 protein_coding_gene 0042060=wound healing BcDNA:SD18306 IPR028108=Protein of unknown function DUF4505 CG30010 16-Dec-15 2015_12 WBGene00044251(F59C6.12) ENSMUSG00000079002(C030006K11Rik) ENSG00000213563(C8orf82) viable FBgn0037084 Syx6 Syntaxin 6 http://flybase.net/reports/FBgn0037084.html protein_coding_gene 0005484=SNAP receptor activity "0016192=vesicle-mediated transport, 0016081=synaptic vesicle docking, 0048193=Golgi vesicle transport, 0007269=neurotransmitter secretion" "0031201=SNARE complex, 0005886=plasma membrane" "CT23545, Syx, SYX6/10, DmSyx6, SYN6, CG7736, Dm Syx6, syntaxin, Syntaxin" "IPR000727=Target SNARE coiled-coil homology domain, IPR010989=t-SNARE, IPR015260=Syntaxin 6, N-terminal" CG7736 16-Dec-15 2015_12 ENSDARG00000042742(stx6) "ENSXETG00000023132(STX6),ENSXETG00000005589(STX10)" "ENSG00000104915(STX10),ENSG00000135823(STX6)" "viable,fertile" FBgn0053844 His2A:CG33844 His2A:CG33844 http://flybase.net/reports/FBgn0053844.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly "0005634=nucleus, 0000786=nucleosome" CG33844 "IPR007125=Histone H2A/H2B/H3, IPR002119=Histone H2A, IPR009072=Histone-fold" CG33844 16-Dec-15 2015_12 "ENSDARG00000052449,ENSDARG00000068995(zgc:101846),ENSDARG00000070277,ENSDARG00000036921,ENSDARG00000051732(zgc:173552),ENSDARG00000051770(LOC100333384),ENSDARG00000070255,ENSDARG00000070286,ENSDARG00000070265(LOC100004768),ENSDARG00000067940,ENSDARG00000070258,ENSDARG00000067931,ENSDARG00000068051,ENSDARG00000068044,ENSDARG00000068059,ENSDARG00000052445,ENSDARG00000051775(LOC100333205),ENSDARG00000051736(zgc:114037),ENSDARG00000051734(LOC560309),ENSDARG00000067886,ENSDARG00000036919,ENSDARG00000068056,ENSDARG00000070296,ENSDARG00000036927,ENSDARG00000036917,ENSDARG00000067880,ENSDARG00000070280(zgc:173652),ENSDARG00000068039,ENSDARG00000068928(LOC100332885),ENSDARG00000051716,ENSDARG00000029406(h2afx)" "YBL003C(HTA2),YDR225W(HTA1)" "WBGene00001909(his-35),WBGene00001877(his-3)" "ENSXETG00000025391(),ENSXETG00000016179(H2AFX),ENSXETG00000027849(h2afj),ENSXETG00000026075(hist2h2ab),ENSXETG00000025687(),ENSXETG00000025393(),ENSXETG00000026682(),ENSXETG00000013777(),ENSXETG00000021560(TNeu117f13.1),ENSXETG00000026675(),ENSXETG00000021561()" "ENSMUSG00000068855(Hist2h2ac),ENSMUSG00000060032(H2afj),ENSMUSG00000063689(Hist2h2ab),ENSMUSG00000063954(Hist2h3c1),ENSMUSG00000064220(Hist2h2aa1),ENSMUSG00000078851(Hist3h2a),ENSMUSG00000071516(Hist1h2ai),ENSMUSG00000069304,ENSMUSG00000069272(Hist1h2ae),ENSMUSG00000061615(Hist1h2ab),ENSMUSG00000060262(Hist1h2ao),ENSMUSG00000069309(Hist1h2an),ENSMUSG00000069301(Hist1h2ag),ENSMUSG00000071478(Hist1h2ad),ENSMUSG00000069270(Hist1h2ac),ENSMUSG00000061991(Hist1h2af),ENSMUSG00000063021(Hist1h2ak),ENSMUSG00000069302(Hist1h2ah),ENSMUSG00000049932(H2afx),ENSMUSG00000060081(Hist1h2aa)" "ENSG00000180573(HIST1H2AC),ENSG00000184270(HIST2H2AB),ENSG00000183558(HIST2H2AA3),ENSG00000203812(HIST2H2AA4),ENSG00000181218(HIST3H2A),ENSG00000198374(HIST1H2AL),ENSG00000196747(HIST1H2AI),ENSG00000184348(HIST1H2AK),ENSG00000196787(HIST1H2AG),ENSG00000196866(HIST1H2AD),ENSG00000184260(HIST2H2AC),ENSG00000168274(HIST1H2AE),ENSG00000137259(HIST1H2AB),ENSG00000184825(HIST1H2AH),ENSG00000164508(HIST1H2AA),ENSG00000182611(HIST1H2AJ),ENSG00000197409(HIST1H3D),ENSG00000188486(H2AFX),ENSG00000111332" FBgn0032005 Snx6 Sorting nexin 6 http://flybase.net/reports/FBgn0032005.html protein_coding_gene "0008565=protein transporter activity, 0032266=phosphatidylinositol-3-phosphate binding" "0061357=positive regulation of Wnt protein secretion, 0060070=canonical Wnt signaling pathway, 0042147=retrograde transport, endosome to Golgi, 0006886=intracellular protein transport" "0005768=endosome, 0030905=retromer complex, outer shell" "CG8282, SNX6, DmSNX6, Snx6, Dsnx6" "IPR001683=Phox homologous domain, IPR015404=Sorting nexin Vps5-like, C-terminal, IPR014637=Sorting nexin-5/6/32, IPR027267=Arfaptin homology (AH) domain/BAR domain" CG8282 16-Dec-15 2015_12 "ENSDARG00000058444(snx6),ENSDARG00000020442(snx5)" "ENSXETG00000012302(snx6),ENSXETG00000000776(snx5)" "ENSMUSG00000005656(Snx6),ENSMUSG00000056185(Snx32),ENSMUSG00000027423(Snx5)" "ENSG00000129515(SNX6),ENSG00000172803(SNX32),ENSG00000089006(SNX5)" "viable,fertile" FBgn0085370 Pde11 Phosphodiesterase 11 http://flybase.net/reports/FBgn0085370.html "FBgn0032686, FBgn0032687" protein_coding_gene "0047555=3',5'-cyclic-GMP phosphodiesterase activity, 0004115=3',5'-cyclic-AMP phosphodiesterase activity" "0046331=lateral inhibition, 0007165=signal transduction, 0046068=cGMP metabolic process, 0046058=cAMP metabolic process" 0005829=cytosol "PDE11, CG34341, Phosphodiesterase 11, CG10231, CG15159" "IPR023088=3'5'-cyclic nucleotide phosphodiesterase, IPR023174=3'5'-cyclic nucleotide phosphodiesterase, conserved site, IPR003607=HD/PDEase domain, IPR002073=3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003018=GAF domain, IPR029016=GAF domain-like" CG34341 16-Dec-15 2015_12 "ENSDARG00000063732(pde11a),ENSDARG00000006151(pde11al)" WBGene00016328(pde-5) ENSXETG00000008465(PDE11A) ENSMUSG00000075270(Pde11a) ENSG00000138735(PDE5A) DRSC02460 I 1.540155241 2.585501496 0.480045917 0.778721416 0.056043881 1.452449857 FBgn0053833 His3:CG33833 His3:CG33833 http://flybase.net/reports/FBgn0053833.html protein_coding_gene "0003677=DNA binding, 0046982=protein heterodimerization activity" 0006333=chromatin assembly or disassembly 0000786=nucleosome CG33833 "IPR007125=Histone H2A/H2B/H3, IPR009072=Histone-fold, IPR000164=Histone H3/CENP-A" CG33833 16-Dec-15 2015_12 "ENSDARG00000070262,ENSDARG00000068053,ENSDARG00000052440,ENSDARG00000068062,ENSDARG00000058490,ENSDARG00000070252(LOC100334933),ENSDARG00000067883,ENSDARG00000051776(LOC100332949),ENSDARG00000068046,ENSDARG00000051772,ENSDARG00000051733,ENSDARG00000068941(zgc:113983),ENSDARG00000058482,ENSDARG00000052448,ENSDARG00000070259(LOC563243),ENSDARG00000068929(LOC100333750),ENSDARG00000068049" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001876(his-2) "ENSXETG00000027186(hist2h3c),ENSXETG00000026674(hist2h3c),ENSXETG00000027196(hist2h3c),ENSXETG00000012442(hist2h3c),ENSXETG00000024969(hist2h3c),ENSXETG00000027504(hist2h3c),ENSXETG00000025582(hist2h3c),ENSXETG00000027201(hist2h3c),ENSXETG00000024982(hist2h3c),ENSXETG00000025343(hist2h3c),ENSXETG00000027513(hist2h3c),ENSXETG00000026970(hist2h3c),ENSXETG00000027575(hist2h3c),ENSXETG00000026670(hist2h3c),ENSXETG00000026730(hist2h3c),ENSXETG00000027963(hist2h3c),ENSXETG00000028011(hist2h3c),ENSXETG00000027854(hist2h3c),ENSXETG00000027141(hist2h3c),ENSXETG00000026683(hist2h3c),ENSXETG00000025964(hist2h3c),ENSXETG00000026119(hist2h3c),ENSXETG00000026972(hist2h3c),ENSXETG00000024976(hist2h3c),ENSXETG00000026405(hist2h3c),ENSXETG00000027511(hist2h3c),ENSXETG00000027961(hist2h3c),ENSXETG00000026363(hist2h3c),ENSXETG00000027576(hist2h3c),ENSXETG00000026740(hist2h3c),ENSXETG00000027851(hist2h3c),ENSXETG00000027507(hist2h3c),ENSXETG00000026078(hist2h3c),ENSXETG00000027843(hist2h3c)" "ENSMUSG00000069273(Hist1h3e),ENSMUSG00000069267(Hist1h3b),ENSMUSG00000075032(Hist1h3c),ENSMUSG00000059309(Hist1h3f),ENSMUSG00000074403(Hist2h3b),ENSMUSG00000062808(Hist1h3d),ENSMUSG00000070392" "ENSG00000203852(HIST2H3A),ENSG00000203811(HIST2H3C),ENSG00000183598(HIST2H3D)" FBgn0266709 Zmynd10 ZMYND10 homolog http://flybase.net/reports/FBgn0266709.html "FBgn0266604, FBgn0036338" protein_coding_gene 0008270=zinc ion binding "0035082=axoneme assembly, 0019230=proprioception, 0007605=sensory perception of sound" 0043025=neuronal cell body "Zmynd10, CG11253" "IPR017333=Uncharacterised conserved protein UCP037948, zinc finger MYND-type, IPR002893=Zinc finger, MYND-type" CG11253 16-Dec-15 2015_12 ENSDARG00000002406(zgc:63660) ENSXETG00000007334(ZMYND10) ENSMUSG00000010044(Zmynd10) ENSG00000004838(ZMYND10) FBgn0032042 CG13398 http://flybase.net/reports/FBgn0032042.html protein_coding_gene 0005158=insulin receptor binding "IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR002404=IRS-type PTB domain" CG13398 16-Dec-15 2015_12 "ENSDARG00000045873(si:dkey-97m3.4),ENSDARG00000037353(frs2)" "ENSXETG00000001426(FRS2),ENSXETG00000011850(FRS3)" "ENSMUSG00000020170(Frs2),ENSMUSG00000023266(Frs3)" ENSG00000175920(DOK7) "viable,visible" trichogen cell FBgn0037010 CG4825 http://flybase.net/reports/FBgn0037010.html protein_coding_gene 0003882=CDP-diacylglycerol-serine O-phosphatidyltransferase activity "0022008=neurogenesis, 0006659=phosphatidylserine biosynthetic process" 0012505=endomembrane system "ptdss1, CDP-diacylglycerol-serine O-phosphatidyltransferase, Phosphatidylserine synthase" IPR004277=Phosphatidyl serine synthase CG4825 16-Dec-15 2015_12 "ENSDARG00000036114(LOC559442),ENSDARG00000012588(ptdss1)" "WBGene00013920(pssy-1),WBGene00012095(pssy-2)" ENSMUSG00000021518(Ptdss1) ENSG00000156471(PTDSS1) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0083953 CG34117 http://flybase.net/reports/FBgn0083953.html protein_coding_gene CG34117 16-Dec-15 2015_12 WBGene00016209(C29E4.12) ENSMUSG00000019689(Fmc1) ENSG00000164898(C7orf55) FBgn0004103 Pp1-87B Protein phosphatase 1 at 87B http://flybase.net/reports/FBgn0004103.html "FBgn0002338, FBgn0003133, FBgn0003597, FBgn0010090, FBgn0011795, FBgn0038044" protein_coding_gene "0017018=myosin phosphatase activity, 0004722=protein serine/threonine phosphatase activity" "0030261=chromosome condensation, 0051225=spindle assembly, 0007067=mitotic nuclear division, 0090307=mitotic spindle assembly, 0007080=mitotic metaphase plate congression, 0008355=olfactory learning, 0000070=mitotic sister chromatid segregation, 0007399=nervous system development, 0040011=locomotion, 0007411=axon guidance, 0048477=oogenesis, 0007611=learning or memory, 0008542=visual learning, 0008344=adult locomotory behavior, 0000022=mitotic spindle elongation, 0007059=chromosome segregation, 0046579=positive regulation of Ras protein signal transduction, 0006909=phagocytosis, 0006470=protein dephosphorylation, 0070374=positive regulation of ERK1 and ERK2 cascade" "0005737=cytoplasm, 0000164=protein phosphatase type 1 complex, 0005700=polytene chromosome" "Ppl-87B, Protein phosphatase 1, Pp1alpha-87B, PP1, Suvar(3)6, Su(var)3-6, Pp-1alpha, su-var(3)6, PPI 87B, PP187B, ck19, dPP1beta, Su-var(3)6, Pp1, DmPp1-87B, PP1alpha-87B, protein phosphatase 1, PP1B, pp1-87B, Su(var)(3)6, PP1alpha87B, 87B, Suppressor of variegation, PP1c 87B, l(3)j6E7, PP1 beta87b, CG5650, Su(Var)3-6, PP-1alpha, PP1c, Pp1-87Bb, PP1alpha[[2]], PP1A87B, PP1-87B, l(3)87Bg, l(3)ck19, PP1 87B" "IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR004843=Calcineurin-like phosphoesterase domain, apaH type, IPR029052=Metallo-dependent phosphatase-like" CG5650 16-Dec-15 2015_12 "ENSDARG00000003486(ppp1caa),ENSDARG00000071566(ppp1cab)" YER133W(GLC7) WBGene00001748(gsp-2) ENSXETG00000024480(ppp1cc) "ENSMUSG00000040385(Ppp1ca),ENSMUSG00000004455(Ppp1cc)" "ENSG00000186298(PPP1CC),ENSG00000172531(PPP1CA)" embryonic stage -- adult stage "lethal,recessive,wild-type,partially lethal - majority die,mitotic cell cycle defective,suppressor of variegation,dominant,visible,somatic clone,non-suppressor of variegation" "nuclear chromosome,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,embryonic/larval optic neuropil,neuroblast,ganglion mother cell,mitosis & nuclear chromosome,imaginal disc,eye photoreceptor cell,somatic clone,eye,eye disc,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF" DRSC27290 IEK 0.336188476 -4.196731104 3.176679563 -5.573582866 -1.344984059 -1.902052782 FBgn0037240 Cont Contactin http://flybase.net/reports/FBgn0037240.html FBan0001084 protein_coding_gene "0019991=septate junction assembly, 0008366=axon ensheathment, 0060857=establishment of glial blood-brain barrier, 0061343=cell adhesion involved in heart morphogenesis, 0021682=nerve maturation, 0007155=cell adhesion, 0045197=establishment or maintenance of epithelial cell apical/basal polarity" "0005886=plasma membrane, 0005918=septate junction, 0005919=pleated septate junction" "D-Axonin, cont, CONT, contactin, CT1481, DCONT, CG1084" "IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR001304=C-type lectin, IPR013151=Immunoglobulin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR003961=Fibronectin type III" CG1084 16-Dec-15 2015_12 "ENSDARG00000019405(zgc:153573),ENSDARG00000062880(LOC569437),ENSDARG00000053454(LOC556251),ENSDARG00000013647(LOC100000688),ENSDARG00000021584(zgc:55318),ENSDARG00000000472,ENSDARG00000045685(cntn1b)" WBGene00016354(rig-6) "ENSXETG00000015810(CNTN1),ENSXETG00000015325(CNTN2),ENSXETG00000005492(CNTN5)" "ENSMUSG00000030075(Cntn3),ENSMUSG00000064293(Cntn4),ENSMUSG00000030092(Cntn6),ENSMUSG00000039488(Cntn5),ENSMUSG00000053024(Cntn2),ENSMUSG00000055022(Cntn1)" "ENSG00000113805(CNTN3),ENSG00000144619(CNTN4),ENSG00000134115(CNTN6),ENSG00000149972(CNTN5),ENSG00000184144(CNTN2),ENSG00000018236(CNTN1)" "lethal,viable,visible" "embryonic epidermis & pleated septate junction,salivary gland,abdominal lateral pentascolopidial chordotonal organ lch5,scolopidium & abdominal lateral pentascolopidial chordotonal organ lch5,septate junction & peripheral glial cell,axolemma & nerve,trichogen cell" FBgn0001091 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 http://flybase.net/reports/FBgn0001091.html FBgn0043822 protein_coding_gene "0004365=glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, 0051287=NAD binding, 0050661=NADP binding" "0055114=oxidation-reduction process, 0006006=glucose metabolic process, 0007520=myoblast fusion, 0007525=somatic muscle development, 0006096=glycolytic process" "0005811=lipid particle, 0005737=cytoplasm, 0030018=Z disc, 0031430=M band" "Glyceraldehyde 3 phosphate dehydrogenase, gapdh, GAP, Gapd, GAPDH, gh12586, GADPH, BEST:GH12586, Glyceraldehyde-3-phosphate dehydrogenase1, gapdh-1, Gapdh43E, Gapdh-1, glyceraldehyde 3 phosphate dehydrogenase1, GA3PDH, G3-P dehydrogenase, GAPDH I, Gapdh, GAPDH1, CG12055, GAPDHI, glyceraldehyde-3-phosphate dehydrogenase, GAPDH-1" "IPR020829=Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR020831=Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR020828=Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR006424=Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020830=Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR016040=NAD(P)-binding domain" CG12055 16-Dec-15 2015_12 ENSDARG00000043457(gapdh) "YGR192C(TDH3),YJL052W(TDH1),YJR009C(TDH2)" "WBGene00001685(gpd-3),WBGene00001684(gpd-2),WBGene00001683(gpd-1),WBGene00001686(gpd-4)" "ENSMUSG00000079501(Gm5138),ENSMUSG00000078965(Gm12033),ENSMUSG00000078162(Gm2574),ENSMUSG00000078967(Gm3272),ENSMUSG00000078088,ENSMUSG00000078142,ENSMUSG00000057666(Gapdh),ENSMUSG00000078592(Gm4609),ENSMUSG00000078191(Gm5559),ENSMUSG00000078300(Gm2606),ENSMUSG00000079360(Gm3839),ENSMUSG00000078573(Gm2451),ENSMUSG00000073212(Gm10481),ENSMUSG00000070025(Gm10284),ENSMUSG00000070490(Gm10293),ENSMUSG00000078636(Gm3200),ENSMUSG00000071813(Gm16374),ENSMUSG00000070443(Gm10291),ENSMUSG00000070408(Gm10290),ENSMUSG00000078370(Gm6316),ENSMUSG00000055676,ENSMUSG00000078308(Gm7293),ENSMUSG00000079558(Gm6981),ENSMUSG00000069236" ENSG00000111640(GAPDH) adult stage viable "embryonic/larval somatic muscle,embryonic myoblast" FBgn0034231 APC10 Anaphase Promoting Complex subunit 10 http://flybase.net/reports/FBgn0034231.html protein_coding_gene 0090302=APC-Cdc20 complex activity "0022008=neurogenesis, 0007067=mitotic nuclear division, 0030071=regulation of mitotic metaphase/anaphase transition, 0007113=endomitotic cell cycle" 0005680=anaphase-promoting complex "APC10, Anaphase promoting complex subunit 10, CG11419, Apc10" "IPR016901=Anaphase-promoting complex, subunit 10, IPR008979=Galactose-binding domain-like, IPR004939=Anaphase-promoting complex, subunit 10/DOC domain" CG11419 16-Dec-15 2015_12 ENSDARG00000060816 YGL240W(DOC1) WBGene00044345(Y48G1C.12) ENSXETG00000017613(anapc10) ENSMUSG00000036977(Anapc10) ENSG00000164162(ANAPC10) "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0263933 ebi ebi http://flybase.net/reports/FBgn0263933.html "FBgn0023444, FBgn0021820, FBgn0085068" protein_coding_gene "0005515=protein binding, 0070491=repressing transcription factor binding, 0001106=RNA polymerase II transcription corepressor activity, 0005525=GTP binding, 0003682=chromatin binding" "0022416=chaeta development, 0006979=response to oxidative stress, 0045747=positive regulation of Notch signaling pathway, 0070050=neuron cellular homeostasis, 0007173=epidermal growth factor receptor signaling pathway, 0045892=negative regulation of transcription, DNA-templated, 0051726=regulation of cell cycle, 0035220=wing disc development, 0045572=positive regulation of imaginal disc growth, 0030162=regulation of proteolysis, 0007219=Notch signaling pathway, 0046329=negative regulation of JNK cascade, 0042058=regulation of epidermal growth factor receptor signaling pathway, 0042461=photoreceptor cell development, 0042676=compound eye cone cell fate commitment, 0071482=cellular response to light stimulus, 0043524=negative regulation of neuron apoptotic process, 0031065=positive regulation of histone deacetylation" "0005700=polytene chromosome, 0017053=transcriptional repressor complex, 0005634=nucleus" "Ebi, Tbl1, E-2g, E-2f, beta transducin-like 1 protein, FBXW4, CG4063, l(2)k16213, Tb11, Enhancer on chromosome 2-complementation group 2g" "IPR006594=LIS1 homology motif, IPR001680=WD40 repeat, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG4063 16-Dec-15 2015_12 "ENSDARG00000058696(zgc:110312),ENSDARG00000008966(zgc:63617),ENSDARG00000060438(tbl1x)" YBR103W(SIF2) "ENSXETG00000001521(tbl1xr1),ENSXETG00000015786()" "ENSMUSG00000025246(Tbl1x),ENSMUSG00000027630(Tbl1xr1)" "ENSG00000101849(TBL1X),ENSG00000092377(TBL1Y),ENSG00000177565(TBL1XR1)" FBgn0034973 CG13564 http://flybase.net/reports/FBgn0034973.html protein_coding_gene 0042742=defense response to bacterium 0005739=mitochondrion "Mitochondrial INner membrane Organizing System 1, Minos1c" IPR007512=Protein of unknown function DUF543 CG13564 16-Dec-15 2015_12 ENSDARG00000070217(zgc:153623) ENSMUSG00000050608(2310028O11Rik) viable DRSC04201 K 0.780892919 -0.090161326 1.215596426 0.402170069 -0.270571265 1.717710358 FBgn0010750 atms antimeros http://flybase.net/reports/FBgn0010750.html "FBgn0011800, FBgn0037274, FBgn0046477, FBgn0046478, FBgn0046479" protein_coding_gene 0019894=kinesin binding "0022008=neurogenesis, 0016570=histone modification, 0006368=transcription elongation from RNA polymerase II promoter, 0045893=positive regulation of transcription, DNA-templated" "0035327=transcriptionally active chromatin, 0016593=Cdc73/Paf1 complex" "anon-WO0172774.114, anon-WO0172774.113, l(3)02466, PAF, PAF1, unnamed, anon-WO0172774.116, l(3)01456, Paf1, l(3)rK509, CG2503, Atms" IPR007133=RNA polymerase II associated factor Paf1 CG2503 16-Dec-15 2015_12 ENSDARG00000043886 YBR279W(PAF1) WBGene00008338(C55A6.9) ENSXETG00000002902(BC064253.1) ENSMUSG00000003437(Paf1) ENSG00000006712(PAF1) "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC27502 EK -1.004259984 1.265092852 3.040033215 -0.268666225 1.357426518 3.362819086 FBgn0030889 CG15373 http://flybase.net/reports/FBgn0030889.html protein_coding_gene IPR022110=Casc1 domain CG15373 16-Dec-15 2015_12 ENSDARG00000016815(casc1) ENSMUSG00000043541(Casc1) ENSG00000118307(CASC1) viable DRSC19663 K -0.431712065 -0.251687335 0.181151162 -0.103639173 1.617624776 0.856345188 FBgn0010423 TpnC47D Troponin C at 47D http://flybase.net/reports/FBgn0010423.html FBgn0064889 protein_coding_gene 0005509=calcium ion binding "TnC, TNC, BcDNA:RE34610, TpnCIb, DmTnC2, CG9073, TnC47D, DmTpnC47D, troponin C, TpnC Ib, DmTpnCIb, TNC47D" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG9073 16-Dec-15 2015_12 WBGene00006583(tnc-2) " embryonic stage | late , larval stage--pupal stage , pupal stage | late , larval stage " organism

"lethal,viable" DRSC07564 K 0.177032847 -0.476977577 0.201616851 -0.132509669 1.738106737 0.313994913 FBgn0030389 CG15927 http://flybase.net/reports/FBgn0030389.html protein_coding_gene CG15927 16-Dec-15 2015_12 viable DRSC19742 K 0.889012232 -0.21945963 -0.38232951 0.132434878 -0.043419496 1.609891924 FBgn0259150 CG42265 http://flybase.net/reports/FBgn0259150.html "FBan0015777, FBgn0029781, FBgn0029780, FBan0017758, FBgn0029782" protein_coding_gene "CG15776, CG15777, CG17758" IPR004878=Otopetrin CG42265 16-Dec-15 2015_12 ENSG00000163982(OTOP1) DRSC18083 K -1.070204438 0.947584682 1.309513414 -0.364345181 1.447018039 2.71422256 FBgn0031391 CG11723 http://flybase.net/reports/FBgn0031391.html protein_coding_gene 0003677=DNA binding 11723 "IPR004210=BESS motif, IPR006578=MADF domain" CG11723 16-Dec-15 2015_12 viable DRSC00324 K 0.617646205 -0.378682456 -0.450174933 0.069845748 1.66499814 -0.371196172 FBgn0034489 ppk6 pickpocket 6 http://flybase.net/reports/FBgn0034489.html protein_coding_gene 0005272=sodium channel activity 0006814=sodium ion transport 0016021=integral component of membrane "CG11209, PPK6" "IPR001873=Na+ channel, amiloride-sensitive" CG11209 16-Dec-15 2015_12 viable DRSC06062 E 0.546940953 -0.064171594 -2.228608228 0.185448126 -0.074169223 -0.225235422 FBgn0035612 CG10625 http://flybase.net/reports/FBgn0035612.html FBgn0062155 protein_coding_gene 0042302=structural constituent of cuticle anon-WO0118547.236 IPR000618=Insect cuticle protein CG10625 16-Dec-15 2015_12 "viable,fertile" DRSC09753 I -1.510333145 0.78026998 -1.020710596 0.370674381 0.022341458 -0.127971482 FBgn0030477 dmrt11E doublesex-Mab related 11E http://flybase.net/reports/FBgn0030477.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0006355=regulation of transcription, DNA-templated, 0007283=spermatogenesis" 0005634=nucleus "doublesex-Mab-related 11E, Dmrt11E, unnamed, CG15749, dmrt11" "IPR026607=DMRT/protein doublesex/protein male abnormal 3, IPR001275=DM DNA-binding domain" CG15749 16-Dec-15 2015_12 "ENSDARG00000015072(dmrt2a),ENSDARG00000070013(dmrt2b)" WBGene00007929(C34D1.1) ENSMUSG00000048138(Dmrt2) ENSG00000173253(DMRT2) viable DRSC19715 E 1.153486101 0.873040502 1.741670415 0.541979184 0.337053422 0.174427173 FBgn0058099 CG40099 http://flybase.net/reports/FBgn0058099.html protein_coding_gene 16-Dec-15 2015_12 DRSC20786 IE -0.1336491 -2.585119333 -0.045680844 -2.305436801 0.095512157 0.056224184 FBgn0034741 CG4269 http://flybase.net/reports/FBgn0034741.html protein_coding_gene cg4269 CG4269 16-Dec-15 2015_12 viable DRSC04457 K 0.388610423 0.24432846 0.590171739 0.032631516 -0.146957915 -1.944911785 FBgn0004924 Top1 Topoisomerase 1 http://flybase.net/reports/FBgn0004924.html "FBgn0027237, FBgn0027261, FBgn0027275, FBgn0040195" protein_coding_gene "0003918=DNA topoisomerase type II (ATP-hydrolyzing) activity, 0003916=DNA topoisomerase activity, 0003677=DNA binding, 0003917=DNA topoisomerase type I activity" "0006265=DNA topological change, 0006260=DNA replication, 0002168=instar larval development, 0030261=chromosome condensation, 0007275=multicellular organismal development, 0006338=chromatin remodeling, 0048477=oogenesis, 0045995=regulation of embryonic development, 0007059=chromosome segregation, 0008283=cell proliferation" "0005665=DNA-directed RNA polymerase II, core complex, 0005737=cytoplasm, 0005829=cytosol, 0005634=nucleus, 0005700=polytene chromosome, 0005730=nucleolus, 0005875=microtubule associated complex, 0031298=replication fork protection complex, 0005719=nuclear euchromatin, 0005703=polytene chromosome puff" "top1, topoI, l(1)G0201, TopoI, Topoisomerase I, topo I, Topo I, TopI, TOP1, l(1)G0134, topoisomerase1, l(1)G0229, type I topoisomerase, topoisomerase I, dTopoI, l(1)G0278, l(1)top1, CG6146, Top 1" "IPR014727=DNA topoisomerase I, catalytic core, alpha/beta subdomain, IPR011010=DNA breaking-rejoining enzyme, catalytic core, IPR013034=DNA topoisomerase I, domain 1, IPR013499=DNA topoisomerase I, eukaryotic-type, IPR013500=DNA topoisomerase I, catalytic core, eukaryotic-type, IPR008336=DNA topoisomerase I, DNA binding, eukaryotic-type, IPR001631=DNA topoisomerase I, IPR014711=DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type, IPR018521=DNA topoisomerase I, active site, IPR025834=Topoisomerase I C-terminal domain, IPR013030=DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type" CG6146 16-Dec-15 2015_12 ENSDARG00000070545(top1l) YOL006C(TOP1) WBGene00006595(top-1) ENSXETG00000019415(TOP1) "ENSMUSG00000000934(Top1mt),ENSMUSG00000070544(Top1)" ENSG00000198900(TOP1) " adult stage , embryonic stage , embryonic stage | early , adult stage | female , embryonic stage -- adult stage " ovary

embryonic stage -- adult stage "viable,increased cell death,recessive,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,wild-type,mitotic cell cycle defective,cell death defective,female sterile,visible" "adult brain,nucleusSgs3.PD,wing,chaeta,melanotic mass,dorsal appendage,follicle cell,germarium,mitotic cell cycle, with Top177,nurse cell & nucleus, with Top177,nurse cell,ectopic,oocyte,mitotic cell cycle | embryonic stage 4, with Top177,mitotic telophase | embryonic stage 4, with Top177,nucleus | embryonic stage 4, with Top177,mitotic cell cycle | embryonic stage 4,nucleus | embryonic stage 4,mitotic cell cycle, with Top1hs.2,nurse cell & nucleus, with Top1hs.2,mitotic cell cycle | embryonic stage 4, with Top1hs.2,mitotic telophase | embryonic stage 4, with Top1hs.2,nucleus | embryonic stage 4, with Top1hs.2,larva,imaginal disc,supernumerary" DRSC20295 I -1.321326334 -2.082754561 -1.30813623 -0.944303279 0.10932181 0.347720493 FBgn0000047 Act88F Actin 88F http://flybase.net/reports/FBgn0000047.html protein_coding_gene 0005200=structural constituent of cytoskeleton "0014866=skeletal myofibril assembly, 0007010=cytoskeleton organization, 0006909=phagocytosis, 0071689=muscle thin filament assembly" 0005884=actin filament "Actin, rsd, F-actin, Ifm(3)7, actin 88F, actin88F, act 88F, Actin88F, Arthrin, act88F, CG5178, Act(88F), actin, E, Act88f, 88F actin, Act88-F, arthrin" "IPR020902=Actin/actin-like conserved site, IPR004001=Actin, conserved site, IPR004000=Actin family" CG5178 16-Dec-15 2015_12 YFL039C(ACT1) pupal stage adult stage indirect flight muscle

"flightless,dominant,flight defective,wild-type,semidominant,cold sensitive,visible,recessive,female fertile,reduced,locomotor behavior defective,viable,lethal" "striated muscle thin filament,indirect flight muscle,myofibril,wing,sarcomere,dorsal medial muscle,indirect flight muscle & striated muscle thick filament,indirect flight muscle & striated muscle thin filament,indirect flight muscle & muscle tendon junction,tendon cell,myofibril, with Act88FG15R,Z disc, with Act88FG15R,myofibril, with Act88FI136M,Z disc, with Act88FI136M,myofibril, with Act88FD154N,Z disc, with Act88FD154N,myofibril, with Act88FV163L,Z disc, with Act88FV163L,myofibril, with Act88FV163M,Z disc, with Act88FV163M,myofibril, with Act88FD292V,Z disc, with Act88FD292V,indirect flight muscle & nucleus,myofibril, with Act88F6,Z disc, with Act88F6" DRSC14105 IE -1.848094117 0.269109048 -0.103332891 -1.676953269 1.383607201 1.347735904 FBgn0000459 disco disconnected http://flybase.net/reports/FBgn0000459.html "FBtr0074250, FBpp0074028" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0001158=enhancer sequence-specific DNA binding, 0046872=metal ion binding" "0045893=positive regulation of transcription, DNA-templated, 0007623=circadian rhythm, 0045494=photoreceptor cell maintenance, 0045475=locomotor rhythm, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008062=eclosion rhythm, 0007479=leg disc proximal/distal pattern formation, 0010468=regulation of gene expression, 0007469=antennal development, 0007420=brain development" 0005634=nucleus "Disco, Disconnected, disc, CG9908" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG9908 16-Dec-15 2015_12 " embryonic stage | stage 6 , embryonic stage | stage 15 , embryonic stage | >=6 hr , embryonic stage | stage 11-14 , larval stage--adult stage , embryonic stage | stage 12-15 , embryonic stage | stage 5 , embryonic stage | stage 11 , adult stage , embryonic stage | stage 11-15 , larval stage | third instar " " dorsal ectoderm | restricted

, cephalic furrow | anterior to

, ventral nerve cord

, procephalic segment | restricted

, abdominal segment | ectoderm of

, thoracic segment | ectoderm of

, visceral mesoderm

, amnioproctodeal invagination

,

posterior , proctodeum

, adult head

, gnathal segment

, embryonic optic lobe primordium

, larval brain | restricted

,

0-10% egg length , imaginal disc

, labral segment

" " embryonic stage | stage 6 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage 12-15 , embryonic stage | stage 13-15 , embryonic stage | stage 5 , embryonic stage | stage 12-14 " " cephalic furrow | anterior to

, larval brain | restricted

, amnioproctodeal invagination

, proctodeum

, embryonic optic lobe primordium

, thoracic segment | restricted

, cephalic furrow | posterior to

, labral segment

, visceral mesoderm

, larval optic stalk

, antennal disc

, cardioblast

, lateral ectoderm | segmentally repeated

, ventral nerve cord

, gnathal segment

, ventral thoracic disc

,

0-10% egg length , procephalic segment | restricted

,

posterior , central nervous system | restricted

" "viable,lethal,some die during larval stage,some die during P-stage,partially lethal,temperature conditional,homeotic,circadian rhythm defective,visual behavior defective,recessive,behavior defective,wild-type,mating rhythm defective,female limited,locomotor rhythm defective,locomotor behavior defective,visible,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile" "antenna,leg,tarsal segment,temperature conditional,unguis,third segment of antenna,arista,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,optic lobe,precursor,optic nerve,femur,tibia,lamina,neuron,multidendritic neuron,sensory neuron & leg,sensory neuron & wing,sensory neuron & haltere,central nervous system,prothoracic neuromere,mesothoracic neuromere,metathoracic neuromere,chordotonal organ,mouth hooks,embryonic/larval optic stalk,eye photoreceptor cell & axon & larva,LN Pdf neuron,Pdf neuron close to calyx,l-LNv neuron,Pdf neuron close to tritocerebrum,LNv neuron,eye,ommatidium,pigment cell,cone cell,interommatidial bristle,abdominal ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,extended germ band embryo,dorsal closure embryo,cephalopharyngeal skeleton" FBgn0023495 Lip3 Lip3 http://flybase.net/reports/FBgn0023495.html protein_coding_gene "0016298=lipase activity, 0004806=triglyceride lipase activity" 0006629=lipid metabolic process "LIP3, dLip3, lipase3, Lipase3, LIP3Dm, Lipase-3, dilp3, lipase-3, Dmlip3, lip3, CG8823, lipase 3, dLipase-3" "IPR025483=Lipase, eukaryotic, IPR029058=Alpha/Beta hydrolase fold, IPR006693=Partial AB-hydrolase lipase domain" CG8823 16-Dec-15 2015_12 ENSDARG00000018529(lipf) YKL140W(TGL1) "WBGene00021963(Y57E12B.3),WBGene00010062(F54F3.3),WBGene00020016(R11G11.14),WBGene00022642(ZK6.7),WBGene00009773(F46B6.8)" ENSXETG00000009273(lipA) "ENSMUSG00000024781(Lipa),ENSMUSG00000024768(Lipf),ENSMUSG00000024771(Lipk),ENSMUSG00000056078,ENSMUSG00000024770(Lipn),ENSMUSG00000079344(Gm6857),ENSMUSG00000024766(AI747699),ENSMUSG00000079342(Gm5097)" "ENSG00000182333(LIPF),ENSG00000204021(LIPK),ENSG00000204022(LIPJ),ENSG00000204020(LIPN),ENSG00000173239(LIPM),ENSG00000107798(LIPA)" " larval stage | first instar , adult stage | female , oogenesis stage | stage S10 , larval stage | second instar , larval stage , embryonic stage " "

late , ovary

, follicle cell

, embryonic/larval fat body

, oocyte

" viable FBgn0000181 bic bicaudal http://flybase.net/reports/FBgn0000181.html "FBgn0002068, FBgn0004676, FBgn0021942, FBgn0027918" protein_coding_gene "0007317=regulation of pole plasm oskar mRNA localization, 0060811=intracellular mRNA localization involved in anterior/posterior axis specification, 0070201=regulation of establishment of protein localization" "0005875=microtubule associated complex, 0005854=nascent polypeptide-associated complex" "5A, BcDNA:GM05329, l(2)k10712, l(2)vr22, E(2)Bic, E(Bic), l(2)49Da, 107/12, Enhancer of Bicaudal, CG3644, Bic, vr22, Btf, BcDNA.GM05329" IPR002715=Nascent polypeptide-associated complex NAC domain CG3644 16-Dec-15 2015_12 "ENSDARG00000070719,ENSDARG00000070722(LOC100006097),ENSDARG00000035400(btf3)" "YPL037C(EGD1),YDR252W(BTT1)" WBGene00002045(icd-1) "ENSXETG00000008056(btf3l4),ENSXETG00000016819(btf3)" "ENSMUSG00000028568(Btf3l4),ENSMUSG00000021660(Btf3)" "ENSG00000134717(BTF3L4),ENSG00000145741(BTF3)" " embryonic stage | late , adult stage && oogenesis stage , adult stage | female , adult stage | male , embryonic stage , embryonic stage | stage <=8 , adult stage && oogenesis stage | stage S3-10 , adult stage && oogenesis stage | stage >=S10 , embryonic stage | extended germ band " " pharyngeal muscle

, germarium region 2b

, embryonic/larval somatic muscle | subset

, embryonic central nervous system

, ovary

, organism

, nurse cell

, oocyte

, mesoderm

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,dominant,wild-type,maternal effect,non-suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,embryo,anterior,egg,embryonic head,embryonic segment,maternal effect,denticle belt,embryonic/larval posterior spiracle,Malpighian tubule,genital disc,amnioproctodeal invagination,cephalopharyngeal skeleton" FBgn0260400 elav embryonic lethal abnormal vision http://flybase.net/reports/FBgn0260400.html "FBgn0026157, FBgn0000570, FBgn0040177, FBgn0040203" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0003723=RNA binding, 0008266=poly(U) RNA binding" "0007399=nervous system development, 0031441=negative regulation of mRNA 3'-end processing, 0007417=central nervous system development, 0016070=RNA metabolic process" "0015030=Cajal body, 0005634=nucleus" "embryonic lethal, abnormal vision, ELAV, l(1)G0031, elav-3, 9F8A9, Embryonic lethal abnormal visual system, CG4262, fliJ, Embryonic lethal abnormal vision, END1-2, Elav-9F8A9, weniger, elav-2, Embryonic Lethal Abnormal Vision, l(1)EC7, l(1)1Be, 44C11, ElaV, Elav, l(1)G0319, elav-1, EG:65F1.2, weg, embryonic lethal abnormal visual system, EC7" "IPR000504=RNA recognition motif domain, IPR002343=Paraneoplastic encephalomyelitis antigen, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006548=Splicing factor ELAV/HuD" CG4262 16-Dec-15 2015_12 YCL011C(GBP2) WBGene00001368(exc-7) " embryonic stage | stage 13-14 , embryonic stage| 6-18 hr , embryonic stage , adult stage , larval stage | third instar , embryonic stage | stage 11-14 , embryonic stage | 6-18 hr , embryonic stage | 6-12 hr , pharate adult stage | stage P15 " " dorsal ectoderm

segmentally repeated , Johnston's organ

, ventral nerve cord

, embryonic central nervous system | presumptive

, embryonic nervous system

, morphogenetic furrow | posterior to

, thoracico-abdominal ganglion

, larval brain

" " pupal stage | 12-50 hr , adult stage , pupal stage | 72 hr , pupal stage | 12 hr , embryonic stage | stage 11-16 , larval stage | third instar , pupal stage | stage P9 , embryonic stage | stage 13-15 , pupal stage--adult stage , embryonic stage | stage 11-15 " " ocellus | presumptive

, photoreceptor cell R1--8

, ocellus

, retina

, lamina cortex

, lobula plate cortex

, eye-antennal disc

, embryonic/larval nervous system

, thoracico-abdominal ganglion

, monopolar laminar cell

, larval brain

, peripheral nervous system

, eye

, medulla cortex

, adult brain

, central nervous system

, antenna

" FBgn0016075 vkg viking http://flybase.net/reports/FBgn0016075.html FBgn0010477 protein_coding_gene 0005201=extracellular matrix structural constituent "0007519=skeletal muscle tissue development, 0007443=Malpighian tubule morphogenesis, 0061327=anterior Malpighian tubule development" "0005581=collagen trimer, 0005587=collagen type IV trimer, 0005811=lipid particle" "collagenIV a2, DmColA2, coll-IV, type IV collagen, alpha-chain, VkgC, Viking, CG16858, collagen IV, type IV collagenS, Type IV collagen, Vkg, alpha(IV)2/vkg, Collagen IV, CT25584, collagen IV alpha2, 6072, Coll IValpha2, 1209, col4a2, coll. IV, l(2)01209, collagen-IV" "IPR001442=Collagen IV, non-collagenous, IPR016187=C-type lectin fold, IPR008160=Collagen triple helix repeat" CG16858 16-Dec-15 2015_12 ENSDARG00000002831(col4a4) ENSXETG00000002637(COL4A1) " embryonic stage | stage 16-17 , embryonic stage | stage 15-16 , larval stage | first instar " " embryonic/larval fat body

, embryonic/larval hemocyte

" "viable,lethal,recessive,short lived,hypoactive,locomotor behavior defective" "embryonic anterior Malpighian tubule,A1-7 segment border muscle" FBgn0036964 FRG1 FSHD region gene 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0036964.html protein_coding_gene "0070511=negative regulation of histone H4-K20 methylation, 0031936=negative regulation of chromatin silencing" "dFRG1, CG6480, FRG1" "IPR010414=FRG1-like, IPR008999=Actin cross-linking" CG6480 16-Dec-15 2015_12 ENSDARG00000056504(zgc:112426) WBGene00014177(frg-1) ENSXETG00000012470(frg1) ENSMUSG00000031590(Frg1) "ENSG00000109536(FRG1),ENSG00000149531" "viable,enhancer of variegation" DRSC10648 K 0.291032651 0.214827884 -0.123849426 0.339932328 1.802058547 -0.240082729 FBgn0001325 Kr Kruppel http://flybase.net/reports/FBgn0001325.html "FBgn0001251, FBgn0015732" protein_coding_gene "0043565=sequence-specific DNA binding, 0003682=chromatin binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0061332=Malpighian tubule bud morphogenesis, 0007400=neuroblast fate determination, 0040034=regulation of development, heterochronic, 0035206=regulation of hemocyte proliferation, 0035220=wing disc development, 0048749=compound eye development, 0007354=zygotic determination of anterior/posterior axis, embryo, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007419=ventral cord development, 0007402=ganglion mother cell fate determination, 0045892=negative regulation of transcription, DNA-templated, 0007517=muscle organ development, 0007443=Malpighian tubule morphogenesis, 0006342=chromatin silencing, 0007411=axon guidance, 0035290=trunk segmentation, 0010629=negative regulation of gene expression" 0005634=nucleus "Kruppel, Irregular facets, Lruppel, krueppel, Krpple, CG3340, kruppel, KR, If, kr, KRUPPEL, Dm-Kr, Krueppel, Kuppel" "IPR031243=Protein krueppel, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG3340 16-Dec-15 2015_12 "ENSDARG00000007990(wt1b),ENSDARG00000031420(wt1a)" "YPR015C(),YPR013C()" WBGene00015138(B0310.2) " embryonic stage | stage 14 , embryonic stage | stage 4-10 , embryonic stage | stage >=12 , embryonic stage | blastoderm , embryonic stage | early , embryonic stage--pupal stage , embryonic stage | stage 4 " " embryonic brain

, Bolwig's organ

, embryonic/larval nervous system

, organism | 40-60% egg length

,

medial , embryonic/larval muscle system

,

40-60% egg length " " embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | stage > 9 " " embryonic Malpighian tubule tip cell

, adult muscle precursor primordium | restricted

,

40-60% egg length , embryonic Malpighian tubule

" "visible,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,heat sensitive,viable,melanotic mass phenotype" "embryonic/larval posterior Malpighian tubule,embryonic/larval anterior Malpighian tubule,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,eye,embryonic segment,embryonic abdominal segment 4,embryonic/larval hemocyte | third instar larval stage,mesothoracic segment,metathoracic segment,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic prothoracic segment,embryonic abdominal segment 5,embryonic/larval ureter,embryonic/larval Malpighian tubule,embryonic/larval midgut,posterior,embryonic/larval hindgut,Malpighian tubule,extended germ band embryo,Malpighian tubule tip cell,U3 neuron,ectopic,heat sensitive,A1-7 dorsal acute muscle 1,A1-7 lateral longitudinal muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 4,A1-7 ventral acute muscle 2,A1-7 ventral oblique muscle 2,A1-7 ventral oblique muscle 5,mesoderm,ganglion mother cell GMC1-1a,EW2 neuron,EW1 neuron,EW3 neuron,neuroblast NB7-1,abdominal segment 6,abdominal segment 7,ommatidium,eye disc,rhabdomere,adult cuticle,embryonic abdomen,anterior,Malpighian tubule primordium,midgut constriction,embryonic/first instar larval cuticle,larval thorax,larval abdomen,thorax,abdomen,larval abdominal segment,commissure,longitudinal connective,serotonergic neuron,glial cell,larval mesothoracic segment,adult mesothoracic segment,embryonic abdominal segment,embryonic Malpighian tubule,retina,ventral,neuroblast NB7-3,RP neuron,abdominal segmental nerve,A1-7 lateral transverse muscle,abdominal 2 ventral acute muscle 1,abdominal 3 ventral acute muscle 1,abdominal 4 ventral acute muscle 1,abdominal 5 ventral acute muscle 1,abdominal 6 ventral acute muscle 1,abdominal 7 ventral acute muscle 1,lamellocyte | third instar larval stage" DRSC04622 E 0.672396289 0.475605192 2.818499435 -0.015846986 -0.409549783 -0.406273937 FBgn0023458 Rbcn-3A Rabconnectin-3A http://flybase.net/reports/FBgn0023458.html FBgn0015656 protein_coding_gene "0007035=vacuolar acidification, 0007424=open tracheal system development, 0008593=regulation of Notch signaling pathway" "DmX, Rabconnectin-3alpha, anon-X, FV10, X, Dmx, CG3585" "IPR001680=WD40 repeat, IPR022033=RAVE complex protein Rav1 C-terminal, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain" CG3585 16-Dec-15 2015_12 ENSDARG00000061570(rc3) WBGene00004313(rbc-1) "ENSXETG00000020770(DMXL2),ENSXETG00000017568(DMXL1)" "ENSMUSG00000041268(Dmxl2),ENSMUSG00000037416(Dmxl1)" "ENSG00000104093(DMXL2),ENSG00000172869(DMXL1)" "lethal,recessive" "follicle cell,somatic clone,tracheal system" DRSC28199 K 0.228527559 0.371090088 0.262247897 -0.954628277 0.023753493 2.893083909 FBgn0021967 ND-PDSW NADH dehydrogenase (ubiquinone) PDSW subunit http://flybase.net/reports/FBgn0021967.html "FBgn0027663, FBgn0031539, FBgn0062981" protein_coding_gene "0008137=NADH dehydrogenase (ubiquinone) activity, 0003954=NADH dehydrogenase activity" "0022008=neurogenesis, 0006120=mitochondrial electron transport, NADH to ubiquinone" "0005739=mitochondrion, 0005747=mitochondrial respiratory chain complex I" "NIDM, BcDNA:RE65754, pdsw, CG8844, NADH-ubiquinone oxidoreductase PDSW subunit, l(2)k10101, anon-EST:Posey91, PDSW, Pdsw, NADH:ubiquinone oxidoreductase PDSW subunit, NADH ubiquinone oxidoreductase PDSW" "IPR019377=NADH-ubiquinone oxidoreductase, subunit 10" CG8844 16-Dec-15 2015_12 ENSDARG00000028889(LOC100329533) WBGene00010326(F59C6.5) ENSXETG00000020351(NDUFB10) ENSMUSG00000040048(Ndufb10) ENSG00000140990(NDUFB10) "lethal,recessive,visible,somatic clone,neuroanatomy defective,viable,increased cell number" "eye,somatic clone,eye disc,lens,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,lamellocyte | third instar larval stage" DRSC00715 E 1.117392107 0.166467193 1.702471519 -1.287106062 1.262416431 0.174012208 FBgn0260934 par-1 par-1 http://flybase.net/reports/FBgn0260934.html "FBgn0026193, FBgn0022139, FBgn0034448, FBgn0034449, FBgn0034450, FBgn0050131, FBgn0050132, FBgn0061180, FBgn0064805, FBgn0065111, FBgn0026655" protein_coding_gene "0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0050321=tau-protein kinase activity" "0051663=oocyte nucleus localization involved in oocyte dorsal/ventral axis specification, 0009948=anterior/posterior axis specification, 0007314=oocyte anterior/posterior axis specification, 0090176=microtubule cytoskeleton organization involved in establishment of planar polarity, 0009798=axis specification, 0008360=regulation of cell shape, 0007276=gamete generation, 0001737=establishment of imaginal disc-derived wing hair orientation, 0006468=protein phosphorylation, 0019730=antimicrobial humoral response, 0007015=actin filament organization, 0000226=microtubule cytoskeleton organization, 0030709=border follicle cell delamination, 0035332=positive regulation of hippo signaling, 0007298=border follicle cell migration, 0045185=maintenance of protein location, 0007294=germarium-derived oocyte fate determination, 0001933=negative regulation of protein phosphorylation, 0045451=pole plasm oskar mRNA localization, 0030707=ovarian follicle cell development, 0007317=regulation of pole plasm oskar mRNA localization, 0007318=pole plasm protein localization, 0051124=synaptic growth at neuromuscular junction, 0030111=regulation of Wnt signaling pathway, 0016325=oocyte microtubule cytoskeleton organization, 0009994=oocyte differentiation" "0005938=cell cortex, 0045172=germline ring canal, 0045169=fusome, 0016323=basolateral plasma membrane, 0031594=neuromuscular junction, 0061174=type I terminal bouton" "Par-1 kinase, BcDNA:RH48823, lethal (2) 27C1, dPAR-1, CG30132, 27C1, dMARK, DPAR-1, ELKL motif kinase, par1, dPar1, anon-WO0210402.19, l(2)27C1, Par-1, l(2)k06323, partitioning defective-1, CG8201, PAR1, C-TAK1-like, MARK, CG30131, CG11960, PAR1/MARK2, Par1, dPAR1, CG16701, EMK, dPar-1, DPar1, PAR-1, Par-1 protein kinase" "IPR000719=Protein kinase domain, IPR001772=Kinase associated domain 1 (KA1), IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR028375=KA1 domain/Ssp2 C-terminal domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR015940=Ubiquitin-associated domain, IPR017441=Protein kinase, ATP binding site" CG8201 16-Dec-15 2015_12 "ENSDARG00000026630(zgc:153725),ENSDARG00000019345(mark3),ENSDARG00000032458(mark2),ENSDARG00000023914(LOC569346),ENSDARG00000024966(LOC571279)" "YLR096W(KIN2),YDR122W(KIN1)" "ENSXETG00000012767(MARK3),ENSXETG00000002704(mark2)" "ENSMUSG00000007411(Mark3),ENSMUSG00000026620(Mark1),ENSMUSG00000030397(Mark4),ENSMUSG00000024969(Mark2)" "ENSG00000116141(MARK1),ENSG00000072518(MARK2),ENSG00000075413(MARK3),ENSG00000007047(MARK4)" adult stage && oogenesis stage " follicle cell

, oocyte

, nurse cell

" ", adult stage && oogenesis stage | stage S9,10 , oogenesis stage && adult stage | female , adult stage && oogenesis stage , adult stage | female && oogenesis stage | stage S9 , adult stage | female && oogenesis stage | stage S10 " " germarium region 2b && presumptive oocyte | anterior , oocyte | anterior posterior gradient , germarium

, nurse cell ring canal

, stage S3 oocyte

posterior , oocyte | anterior

, follicle cell

, germarium region 1 | ubiquitous & female germline stem cell | ubiquitous

, germarium region 3 && stage S1 oocyte | posterior , germarium region 1 && cystoblast , oocyte | posterior

, stage S5 oocyte

posterior " DRSC07660 K -0.730142184 -1.328089399 -0.169754279 -1.39658169 1.338142879 1.684718003 FBgn0025678 CaBP1 calcium-binding protein 1 http://flybase.net/reports/FBgn0025678.html "FBgn0027896, FBgn0028505" protein_coding_gene 0003756=protein disulfide isomerase activity "2000427=positive regulation of apoptotic cell clearance, 0045454=cell redox homeostasis" "0005811=lipid particle, 0012505=endomembrane system, 0005783=endoplasmic reticulum" "DmCaBP1, AAL28897, BG:DS09218.4, CG5809, CaBP1" "IPR013766=Thioredoxin domain, IPR017937=Thioredoxin, conserved site, IPR012336=Thioredoxin-like fold, IPR005788=Disulphide isomerase" CG5809 16-Dec-15 2015_12 ENSDARG00000009001(pdip5) YIL005W(EPS1) WBGene00015168(tag-320) ENSXETG00000003512(pdia6) ENSMUSG00000020571(Pdia6) ENSG00000143870(PDIA6) " embryonic stage , embryonic stage | stage 5 , embryonic stage | stage >=6 , embryonic stage | extended germ band , embryonic stage | syncytial blastoderm , embryonic stage | stage >8 " " embryonic/larval muscle system

, organism | striped

, ventral midline

,

anterior , embryonic head | posterior

,

posterior ,

ubiquitous " "viable,fertile" FBgn0033027 TpnC4 Troponin C isoform 4 http://flybase.net/reports/FBgn0033027.html FBgn0047054 protein_coding_gene 0005509=calcium ion binding "DmTnC4, Troponin C4, DmTpnCIIIb, troponin-C, TpnCIIIb, TnC4, TNC41F6, TpnC4, tnC4, TnC, TpnC IIIb, CG12408, DmTpnC41F, BcDNA:RH03361, Troponin C 41F, TpnC41F, troponin C" "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG12408 16-Dec-15 2015_12 larval stage--adult stage organism

adult stage indirect flight muscle

FBgn0027453 Dnz1 DNZDHHC/NEW1 zinc finger protein 11 http://flybase.net/reports/FBgn0027453.html protein_coding_gene "0008270=zinc ion binding, 0019706=protein-cysteine S-palmitoyltransferase activity" "0046331=lateral inhibition, 0018345=protein palmitoylation" 0005783=endoplasmic reticulum "CG6627, DNZDHHC/NEW1 zinc-finger protein 11, DNZ1" "IPR001594=Zinc finger, DHHC-type, palmitoyltransferase" CG6627 16-Dec-15 2015_12 ENSDARG00000030563(zgc:77880) YLR246W(ERF2) WBGene00007637(C17D12.1) ENSXETG00000017674(TEgg015i10.1) " embryonic stage | syncytial blastoderm , embryonic stage -- adult stage " "viable,visible" chaeta FBgn0001105 Gë_13F G protein ë_-subunit 13F http://flybase.net/reports/FBgn0001105.html protein_coding_gene 0003924=GTPase activity "0061343=cell adhesion involved in heart morphogenesis, 0007015=actin filament organization, 0045176=apical protein localization, 0007186=G-protein coupled receptor signaling pathway, 0055059=asymmetric neuroblast division" "0005886=plasma membrane, 0005834=heterotrimeric G-protein complex, 0005875=microtubule associated complex" "clone 1.22, gbeta13F, Gbeta, G[[beta]] brain, anon-EST:Liang-1.22, G-beta, Gbeta13F, G-protein beta 13F, dgbeta, G b13F, G[[beta]], G[[beta13F]], G protein beta subunit, Gbb, G-betab, Gb13F, G protein beta-subunit 13F, CG10545" "IPR016346=Guanine nucleotide-binding protein, beta subunit, IPR015943=WD40/YVTN repeat-like-containing domain, IPR017986=WD40-repeat-containing domain, IPR019775=WD40 repeat, conserved site, IPR020472=G-protein beta WD-40 repeat, IPR001680=WD40 repeat, IPR001632=G-protein, beta subunit" CG10545 16-Dec-15 2015_12 "ENSDARG00000060360(gnb1l),ENSDARG00000005944(LOC100150215),ENSDARG00000035357(gnb2)" YOR212W(STE4) WBGene00001679(gpb-1) ENSXETG00000007259(gnb4) "ENSMUSG00000029064(Gnb1),ENSMUSG00000029713(Gnb2),ENSMUSG00000027669(Gnb4)" "ENSG00000078369(GNB1),ENSG00000114450(GNB4),ENSG00000172354(GNB2)" " embryonic stage | mid-late , embryonic stage , embryonic stage -- adult stage , adult stage , embryonic stage | early , larval stage--adult stage , pupal stage " " organism

, embryonic central nervous system

, adult brain cortex

, thoracico-abdominal ganglion

, brain

, ovary

" adult stage " thoracico-abdominal ganglion

, neuropil

, adult brain cortex

" "wild-type,lethal,recessive,neuroanatomy defective,germline clone,visible,body color defective,partially lethal - majority die,some die during pupal stage" "spindle & neuroblast,embryonic neuroblast,neuroblast,germline clone,EL neuron,gastrula embryo,embryonic/first instar larval cuticle,anterior,posterior,embryonic neuroblast & spindle | germ-line clone,trichogen cell,mesothoracic tergum" DRSC20247 E 0.78995358 0.624084762 2.563277403 0.712443637 0.050868296 -0.056970294 FBgn0011638 La La autoantigen-like http://flybase.net/reports/FBgn0011638.html FBgn0043798 protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0008098=5S rRNA primary transcript binding" 0006396=RNA processing "0005634=nucleus, 0030529=ribonucleoprotein complex" "ribonucleoprotein La, D-La, dmLa, BEST:LD24519, DLa/SS-B, 38C.38, CG10922, unnamed" "IPR006630=RNA-binding protein Lupus La, IPR000504=RNA recognition motif domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR014886=La protein, RNA-binding domain, IPR002344=Lupus La protein, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10922 16-Dec-15 2015_12 ENSDARG00000029252(ssb) WBGene00016653(C44E4.4) ENSXETG00000025402(SSB) ENSMUSG00000068882(Ssb) ENSG00000138385(SSB) " oogenesis stage , embryonic stage -- adult stage , adult stage && oogenesis stage , embryonic stage | stage 13-16 , embryonic stage | stage 13-15 , embryonic stage | stage 17 , embryonic stage | stage >7 , embryonic stage | early , adult stage && oogenesis stage | stage , nurse cell

, visceral mesoderm

, gonad

, embryonic/larval salivary gland

, mesoderm

,

ubiquitous , follicle cell

" "lethal,recessive,viable,visible" "midgut constriction,midgut constriction 1,midgut constriction 2,midgut constriction 3,embryonic/larval midgut,trichogen cell" FBgn0005427 ewg erect wing http://flybase.net/reports/FBgn0005427.html "FBgn0000609, FBgn0001600" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007517=muscle organ development, 0006357=regulation of transcription from RNA polymerase II promoter, 0007560=imaginal disc morphogenesis, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0007417=central nervous system development, 0030177=positive regulation of Wnt signaling pathway" 0005634=nucleus "CG3114, l(1)VA720, EG:BACR37P7.7, EC3, Erect wing, NRF-1, Ewg, l(1)1Ag, l(1)EC3f, l(1)EC3, l[EC3], Erect Wing, l(1)DA659, erect wings, EWG" "IPR019526=Nuclear respiratory factor-1, activation binding domain, IPR019525=Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain" CG3114 16-Dec-15 2015_12 ENSDARG00000000018(nrf1) ENSXETG00000016306(NRF1) ENSMUSG00000058440(Nrf1) ENSG00000106459(NRF1) embryonic stage " supraesophageal ganglion

, embryonic central nervous system

" " pupal stage | stage P4-7 , embryonic stage , embryonic stage -- adult stage , pupal stage | 10-36hr , embryonic stage && larval stage , pupal stage | 12-36hr " " adult muscle precursor primordium

, neuron

, embryonic central nervous system

, adult myoblast

, dorsal medial muscle | precursor

, coxal tergal remotor muscle | precursor

, mesothoracic extracoxal depressor muscle 66 | precursor

, embryonic peripheral nervous system

, lateral oblique dorsal muscle | precursor

, tergosternal muscle | precursor

" "neuroanatomy defective,RU486 conditional,lethal - all die before end of pupal stage,some die during pupal stage,lethal,some die during first instar larval stage,some die during embryonic stage,wild-type,viable,reduced,lethal - all die before end of embryonic stage,recessive,locomotor behavior defective,somatic clone,flightless,visible,body color defective" "NMJ bouton,RU486 conditional,embryonic/larval neuromuscular junction,synapse | third instar larval stage, with ewg2,indirect flight muscle,dorsal medial muscle,lateral oblique dorsal muscle,somatic clone,synapse | third instar larval stage, with ewgëÓDJ.elav.TIvirHA1,TVSVG,wing,mesothoracic tergum" FBgn0085424 nub nubbin http://flybase.net/reports/FBgn0085424.html "FBgn0032438, FBan0015488, FBgn0002970, FBan0006246, FBgn0032440, FBgn0004393" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0000976=transcription regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007389=pattern specification process, 0036022=limb joint morphogenesis, 0035220=wing disc development, 0007402=ganglion mother cell fate determination, 0006357=regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis, 0007400=neuroblast fate determination, 0002809=negative regulation of antibacterial peptide biosynthetic process, 0007419=ventral cord development" 0005634=nucleus "Nb, nb, dPOU19, Oct1, Pdm1, Oct-1, Nub, CG15488, dPOU-19, NUBBIN, Pdm-1, CG34395, dOct1, PDM1, POU33F1, NUB, pdm, CG6246, nubbin, Nubbin, dPOU-19/pdm-1, Pdm, pdm-1, CG15489, twn, twain, pdm1, POU domain protein 1, PDM-1" "IPR001356=Homeobox domain, IPR010982=Lambda repressor-like, DNA-binding domain, IPR000327=POU-specific domain, IPR013847=POU domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG34395 16-Dec-15 2015_12 "ENSDARG00000011570(pou6f1),ENSDARG00000071722" WBGene00000431(ceh-6) ENSXETG00000006231(pou2f1) "ENSMUSG00000008496(Pou2f2),ENSMUSG00000026565(Pou2f1),ENSMUSG00000032015(Pou2f3)" " embryonic stage | 0-6 hr , larval stage | third instar , embryonic stage | stage16 , larval stage , embryonic stage | cellular blastoderm , embryonic stage | late , embryonic stage | stage 9 , embryonic stage , larval stage--adult stage , embryonic stage | mid , pupal stage , embryonic stage | mid-late , embryonic stage | stage12 , larval stage | second instar , embryonic stage | >=6 hr , larval stage&&pupal stage , embryonic stage | 0-12 hr , embryonic stage | stage 6 " " abdominal basiconical sensillum dbd

, dorsal mesothoracic disc

,

30-50% egg length , bipolar dendrite neuron dorsal thoracic cluster thoracic segment 2..3

{ + BX-C- } , hypophysis

,

segment polarity ,

51-70% egg length{ $ ftz* } , dendritic arborising neuron dorsal abdominal cluster abdominal segment 1..7

{ + BX-C- } , ectoderm | stripes

, embryonic peripheral nervous system | restricted

, embryonic/larval hypopharynx

,

segment polarity{ + BX-C- } , dorsal thoracic bd1

, larval labral segment sense organ

, peripheral nervous system abdominal segment 8..9

{ 0 AS-C{-} } , embryonic/larval pharynx

, parasegment 7

, scolopidial ligament cell lateral abdominal cluster abdominal segment 1..7

{ 0 AS-C{-} } , scolopidial ligament cell &&of dorsal thoracic cluster &&of metathoracic segment && scolopidial ligament cell &&of dorsal thoracic cluster &&of mesothoracic segment

, labral segment

, larval labral segment sense organ | precursor

, scolopidial ligament cell lateral abdominal cluster abdominal segment 1..7

{ + hb* } , neurogenic region

, ventral thoracic disc

, multidendritic sensory organ precursor cell

, optic lobe

, abdominal dorsal multidendritic neuron

, bipolar dendrite neuron dorsal abdominal cluster abdominal segment 1..7

{ + BX-C- } , central nervous system | restricted

,

18-24% egg length{ + hb* } , scolopidial ligament cell lateral abdominal cluster abdominal segment 1..7

{ - abd-A{D24} } , parasegment 11

, dorsal metathoracic disc

, abdominal 1--7 dorsal bipolar neuron dbp

, chordotonal organ &&of lateral thoracic cluster &&of prothoracic segment

, scolopidial ligament cell lateral thoracic cluster thoracic segment 2..3

{ + BX-C- } , abdominal neuroblast &&of abdominal segment 1--7

,

odd pair-rule , larval brain

, scolopidial ligament cell &&of lateral abdominal cluster &&of abdominal segment 1--7

" " embryonic stage | stage 9-11 , larval stage | third instar , embryonic stage | stage 11 , pupal stage , embryonic stage | stage 17 " " deuterocerebral neuroblast | subset

, protocerebral neuroblast | subset

, procephalic neurogenic region | restricted

, dorsal mesothoracic disc

, ganglion mother cell GMC4-2a

, ventral thoracic disc | proximal

, leg & joint | proximal & subset

, EW2 neuron

, tritocerebral neuroblast | subset

" FBgn0003515 st scarlet http://flybase.net/reports/FBgn0003515.html protein_coding_gene "0042626=ATPase activity, coupled to transmembrane movement of substances, 0005524=ATP binding, 0005395=eye pigment precursor transporter activity" "0006727=ommochrome biosynthetic process, 0006856=eye pigment precursor transport, 0006726=eye pigment biosynthetic process, 0006810=transport" "0005887=integral component of plasma membrane, 0043190=ATP-binding cassette (ABC) transporter complex" CG4314 "IPR005284=Pigment precursor permease, IPR017871=ABC transporter, conserved site, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013525=ABC-2 type transporter, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG4314 16-Dec-15 2015_12 YCR011C(ADP1) ENSXETG00000000340(abcg2) " larval stage | third instar , embryonic stage -- adult stage "

{ 0 w1 } "eye color defective,visible,recessive,lethal,sterile,viable,heat sensitive" "pigment cell,heat sensitive" FBgn0032252 loh lonely heart http://flybase.net/reports/FBgn0032252.html protein_coding_gene "0004222=metalloendopeptidase activity, 0008270=zinc ion binding" "0007508=larval heart development, 1901203=positive regulation of extracellular matrix assembly" "0031012=extracellular matrix, 0005578=proteinaceous extracellular matrix" "Loh, CT19510, Lonely heart, CG6232" "IPR010909=PLAC, IPR000884=Thrombospondin type-1 (TSP1) repeat, IPR010294=ADAM-TS Spacer 1, IPR013273=Peptidase M12B, ADAM-TS" CG6232 16-Dec-15 2015_12 "ENSXETG00000018086(ADAMTSL4),ENSXETG00000016384(THSD4)" "ENSMUSG00000032289(Thsd4),ENSMUSG00000015850(Adamtsl4)" "ENSG00000187720(THSD4),ENSG00000143382(ADAMTSL4)" "lethal - all die before end of larval stage,viable,fertile,cell shape defective,short lived" "embryonic/larval heart,embryonic/larval pericardial cell,embryonic/larval heart | third instar larval stage,embryonic/larval pericardial cell | third instar larval stage,embryonic/larval alary muscle,embryonic/larval cardial cell" DRSC02943 K 0.136715505 0.690312826 -0.154288594 0.154037273 0.255737514 -1.820321281 FBgn0040898 CG14809 http://flybase.net/reports/FBgn0040898.html protein_coding_gene 16-Dec-15 2015_12 viable DRSC25685 K -0.651109117 -0.504180537 -0.583297218 0.671164714 -1.675093808 0.04020331 FBgn0035464 CG12006 http://flybase.net/reports/FBgn0035464.html protein_coding_gene 0000030=mannosyltransferase activity 0006506=GPI anchor biosynthetic process 0005789=endoplasmic reticulum membrane unnamed IPR005599=GPI mannosyltransferase CG12006 16-Dec-15 2015_12 ENSDARG00000022744 YGL142C(GPI10) WBGene00020868(eif-1) ENSMUSG00000079469(Pigb) ENSG00000069943(PIGB) viable DRSC08216 I 0.311660652 1.511696428 -0.307452358 0.018435606 -0.206458354 -0.323639497 FBgn0031327 CG5397 http://flybase.net/reports/FBgn0031327.html protein_coding_gene "0052689=carboxylic ester hydrolase activity, 0004772=sterol O-acyltransferase activity" CT16527 "IPR002018=Carboxylesterase, type B, IPR029058=Alpha/Beta hydrolase fold" CG5397 16-Dec-15 2015_12 "viable,visible" mesothoracic tergum DRSC00683 I 1.72657172 -0.153607341 0.16635239 -0.076695907 1.08571374 -0.600846735 FBgn0034387 Cyp12b2 Cyp12b2 http://flybase.net/reports/FBgn0034387.html protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 0020037=heme binding" 0055114=oxidation-reduction process 0005739=mitochondrion "CG15077, 12b2" "IPR017972=Cytochrome P450, conserved site, IPR001128=Cytochrome P450, IPR002401=Cytochrome P450, E-class, group I" CG15077 16-Dec-15 2015_12 "ENSDARG00000058439(cyp27c1),ENSDARG00000045015,ENSDARG00000017028,ENSDARG00000057262(si:dkey-91i10.3),ENSDARG00000055159(zgc:136333),ENSDARG00000069186(LOC795106),ENSDARG00000033802(si:dkeyp-68f9.9),ENSDARG00000070420,ENSDARG00000051860(LOC563363)" WBGene00000375(cyp-44A1) "ENSXETG00000013846(),ENSXETG00000025022(),ENSXETG00000025024(cyp27a1),ENSXETG00000009657(cyp27b1),ENSXETG00000014690()" "ENSMUSG00000038567(Cyp24a1),ENSMUSG00000026170(Cyp27a1)" "ENSG00000019186(CYP24A1),ENSG00000135929(CYP27A1),ENSG00000111012(CYP27B1)" viable DRSC07364 E 0.871501056 0.281365673 -1.952569604 0.397099886 -0.161412626 -0.131167278 FBgn0051283 CG31283 http://flybase.net/reports/FBgn0051283.html protein_coding_gene 16-Dec-15 2015_12 DRSC21585 E 1.246891355 0.208849481 1.320645566 1.50327091 -0.344426186 -0.508844394 FBgn0029979 CG10777 http://flybase.net/reports/FBgn0029979.html protein_coding_gene "0005524=ATP binding, 0003724=RNA helicase activity, 0003676=nucleic acid binding" "cg10777, DmRH1" "IPR000629=ATP-dependent RNA helicase DEAD-box, conserved site, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR011545=DEAD/DEAH box helicase domain, IPR001650=Helicase, C-terminal, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG10777 16-Dec-15 2015_12 "lethal,recessive,viable" DRSC17755 E 0.050851615 -0.604360319 -1.581805473 0.389549804 0.422833257 0.343642908 FBgn0040601 CG13643 http://flybase.net/reports/FBgn0040601.html FBgn0039245 protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG13642 IPR002557=Chitin binding domain CG13643 16-Dec-15 2015_12 viable DRSC14642 K 0.137652897 0.004362843 0.592541484 0.1342383 0.137261914 -1.745520698 FBgn0037106 CG11307 http://flybase.net/reports/FBgn0037106.html protein_coding_gene "0016757=transferase activity, transferring glycosyl groups" CG11307 16-Dec-15 2015_12 "viable,fertile" DRSC11648 E -0.58017616 -0.124858497 -0.642693669 -2.86790718 -0.283064192 0.119311417 FBgn0022069 Nnp-1 Nnp-1 http://flybase.net/reports/FBgn0022069.html FBgn0032508 protein_coding_gene "0006364=rRNA processing, 0000022=mitotic spindle elongation, 0016072=rRNA metabolic process" "0005634=nucleus, 0030688=preribosome, small subunit precursor" "nnp-1, Nnp1, l(2)k07826, NNP-1, CG12396" "IPR010301=Nucleolar, Nop52" CG12396 16-Dec-15 2015_12 ENSDARG00000027515(wu:fi05d01) YDR087C(RRP1) WBGene00008151(C47E12.7) ENSXETG00000013683() "ENSMUSG00000061032(Rrp1),ENSMUSG00000058392(Rrp1b)" "ENSG00000160208(RRP1B),ENSG00000160214(RRP1)" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC02165 IE -1.851885995 0.298341706 2.167803045 -0.631249859 -0.49803586 0.001420522 FBgn0030790 CG4768 http://flybase.net/reports/FBgn0030790.html protein_coding_gene IPR029196=Protein of unknown function DUF4588 CG4768 16-Dec-15 2015_12 "ENSDARG00000012458(zgc:77849),ENSDARG00000055383(zgc:66160)" ENSXETG00000008699(TEgg029f10.1) ENSMUSG00000022507(1810013L24Rik) ENSG00000182831(C16orf72) viable DRSC19917 E 0.365765951 -0.117165246 1.90078 1.249010401 -0.349664918 -0.773762213 FBgn0000422 Ddc Dopa decarboxylase http://flybase.net/reports/FBgn0000422.html FBgn0022245 protein_coding_gene "0004058=aromatic-L-amino-acid decarboxylase activity, 0030170=pyridoxal phosphate binding" "0040007=growth, 0007611=learning or memory, 0006587=serotonin biosynthetic process from tryptophan, 0009611=response to wounding, 0035220=wing disc development, 0006585=dopamine biosynthetic process from tyrosine, 0048082=regulation of adult chitin-containing cuticle pigmentation, 0006584=catecholamine metabolic process, 0040040=thermosensory behavior, 0007619=courtship behavior, 0048066=developmental pigmentation, 0048085=adult chitin-containing cuticle pigmentation, 0043052=thermotaxis, 0007615=anesthesia-resistant memory, 0007616=long-term memory, 0008062=eclosion rhythm" "Dopa decarboxylase, AADC, l(2)k02104, dopamine decarboxylase, CG10697, 3,4-Dihydroxyphenylalanine decarboxylase, l(2)37Bl, dopa-decarboxylase, DDC, l(2)37Ch, unnamed, ddc, dopadecarboxylase, dopa decarboxylase, aromatic L-amino acid decarboxylase, DdcDm, transcription unit No. 3, Dopa Decarboxylase, fDDC, Dopadecarboxylase, 5-HT, DOPA decarboxylase" "IPR015424=Pyridoxal phosphate-dependent transferase, IPR002129=Pyridoxal phosphate-dependent decarboxylase, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR010977=Aromatic-L-amino-acid decarboxylase, IPR021115=Pyridoxal-phosphate binding site" CG10697 16-Dec-15 2015_12 ENSDARG00000016494(ddc) ENSXETG00000004961(DDC) ENSMUSG00000020182(Ddc) ENSG00000132437(DDC) " larval stage | third instar--A , embryonic stage , embryonic stage | early , adult stage , oogenesis stage && adult stage | female , larval stage | third instar " " testis

, ovary

, adult thorax

, adult head

" " adult stage , larval stage , larval stage | third instar , larval stage | third instar--A , embryonic stage | stage 17 , larval stage | third instar stage 2 , adult stage | female " " adult brain | restricted

, ring gland

, adult hindgut

, larval central nervous system

, EW1 neuron

, ventral nerve cord

, epidermis

, larval ventricular ganglion

, recurrent nerve

, neuron | subset

, EW2 neuron

, thoracico-abdominal ganglion | restricted

, frontal ganglion

, glial cell | subset

, larval stomatogastric nervous system

, oviduct

, LP1 neuron

, larval brain | restricted

, larval maxillary nerve

" "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,developmental rate defective,small body,locomotor behavior defective,lethal - all die before end of larval stage,some die during third instar larval stage,partially,visible,wild-type,wound healing defective,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,learning defective,viable,somatic clone,body color defective,lethal - all die before end of pupal stage,some die during pupal stage,flight defective,memory defective" "macrochaeta,cuticle,axillary sclerite,adult cuticle,leg,wing,embryonic/larval heart,somatic clone,microchaeta,triple row,chaeta,wing hair,embryonic/larval cuticle,pupal cuticle,adult thorax,trichogen cell,mesothoracic tergum" FBgn0011771 Hem HEM-protein http://flybase.net/reports/FBgn0011771.html "FBgn0010794, FBgn0026230" protein_coding_gene 0005515=protein binding "0030036=actin cytoskeleton organization, 0001764=neuron migration, 0007520=myoblast fusion, 0008360=regulation of cell shape, 0008407=chaeta morphogenesis, 0001555=oocyte growth, 0007010=cytoskeleton organization, 0030866=cortical actin cytoskeleton organization, 0006909=phagocytosis, 0007409=axonogenesis, 0000902=cell morphogenesis, 0033627=cell adhesion mediated by integrin, 0030031=cell projection assembly, 0007417=central nervous system development, 0007528=neuromuscular junction development" "0005886=plasma membrane, 0031209=SCAR complex, 0005737=cytoplasm" "Kette/Nap1, Kette, Nap1, dhem-2, kette, Nap, hemkette, dhem, Hem1, l(3)03335, HEM, kte, CG5837" IPR019137=Nck-associated protein 1 CG5837 16-Dec-15 2015_12 ENSDARG00000060853(nckap1) WBGene00001580(gex-3) ENSXETG00000001337(NCKAP1) ENSMUSG00000027002(Nckap1) ENSG00000061676(NCKAP1) " embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage | stage 17 , embryonic stage | stage 1-6 , embryonic stage | stage 14-17 , adult stage && oogenesis stage | stage S10 , embryonic stage | stage 7-10 , embryonic stage -- adult stage " " supraesophageal ganglion

,

ubiquitous , embryonic/larval pharynx

, embryonic brain

, ventral nerve cord

, follicle cell

, procephalic neuroblast

, oocyte

" " embryonic stage , "

"neuroanatomy defective,cell migration defective,dominant,lethal,recessive,visible,cell shape defective,viable,poor,wild-type,partially lethal - majority die,some die during pupal stage" "RP2 motor neuron | embryonic stage,intersegmental nerve,axon,neuromuscular junction & synapse,microchaeta,supernumerary,macrochaeta,thecogen cell & actin filament & pupa-537.4,thecogen cell | P-stage,actin filamentb,larval neuromuscular junction & bouton,eye,filamentous actin | pupal stageGMR.PU,actin filament,embryonic/larval neuromuscular junction,adult head & macrochaeta,ventral nerve cord commissure,longitudinal connective,somatic muscle primordium,embryonic/larval somatic muscle,RP2 motor neuron,embryonic myoblast,fusion competent cell,muscle founder cell,actin cytoskeleton,muscle attachment site,S2 cell-line & filopodium | ectopic,S2 cell-line & actin filament | ectopic,lamina plexus,photoreceptor cell & axon,medulla,presumptive embryonic/larval central nervous system,commissure,midline glial cell,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,VUM neuron,ventral midline & neuron,interface glial cell,embryonic/larval midgut,cytoskeleton,cytoskeleton & mesoderm,cytoskeleton & ectoderm,cytoskeleton & embryonic central nervous system,cytoskeleton & embryonic epidermis | dorsal,chaeta" DRSC11865 E 0.608609603 0.112115352 2.676664061 -0.744008192 -0.368223033 0.204963929 FBgn0000253 Cam Calmodulin http://flybase.net/reports/FBgn0000253.html "FBgn0010559, FBgn0015611, FBgn0027677" protein_coding_gene "0005515=protein binding, 0005509=calcium ion binding, 0032036=myosin heavy chain binding, 0031489=myosin V binding, 0070855=myosin VI head/neck binding" "0046331=lateral inhibition, 0016061=regulation of light-activated channel activity, 0051533=positive regulation of NFAT protein import into nucleus, 0046716=muscle cell cellular homeostasis, 2001259=positive regulation of cation channel activity, 2001020=regulation of response to DNA damage stimulus, 0072499=photoreceptor cell axon guidance, 0005513=detection of calcium ion, 0007052=mitotic spindle organization, 0016059=deactivation of rhodopsin mediated signaling, 0090307=mitotic spindle assembly, 0030048=actin filament-based movement, 0007099=centriole replication, 0007605=sensory perception of sound, 0016062=adaptation of rhodopsin mediated signaling, 0051383=kinetochore organization, 0016060=metarhodopsin inactivation, 0007608=sensory perception of smell, 0042052=rhabdomere development, 0016056=rhodopsin mediated signaling pathway, 0035071=salivary gland cell autophagic cell death, 0006468=protein phosphorylation" "0031475=myosin V complex, 0005875=microtubule associated complex, 0005886=plasma membrane, 0005814=centriole, 0030496=midbody, 0005654=nucleoplasm, 0031476=myosin VI complex, 0005819=spindle, 0000922=spindle pole, 0005737=cytoplasm, 0005829=cytosol, 0005813=centrosome, 0016028=rhabdomere" "dCaM, Cal, Cal49A, CAM, CaM, calmodulin, D-CaM, Cam1, l(2)03909, DmCalm, CG8472, DmCaM, 3909, anon-EST:Posey59, l(2)3909, lincRNA.S2634, cam" "IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain, IPR011992=EF-hand domain pair" CG8472 16-Dec-15 2015_12 "ENSDARG00000015050(calm2b),ENSDARG00000044537(calm3a),ENSDARG00000031427(calm2a),ENSDARG00000037014(calm1b),ENSDARG00000021811(calm1a),ENSDARG00000034187(LOC100150680)" YBR109C(CMD1) WBGene00000552(cmd-1) "ENSXETG00000000321(calm1),ENSXETG00000015713(calm1)" "ENSMUSG00000036438(Calm2),ENSMUSG00000019370(Calm3),ENSMUSG00000001175(Calm1)" "ENSG00000160014(CALM3),ENSG00000198668(CALM1)" " adult stage , embryonic stage | mid-late , embryonic stage | mid , embryonic stage | late " " adult head

, embryonic central nervous system | presumptive

, posterior embryonic/larval midgut

, anterior embryonic/larval midgut

, peripheral nervous system

" "lethal,viable,recessive,locomotor behavior defective,wild-type,behavior defective,visual behavior defective,lethal - all die before end of larval stage,some die during larval stage,hypoactive,neurophysiology defective,lethal - all die before end of pupal stage,some die during pupal stage,auditory perception defective,lethal - all die before end of P-stage,some die during pharate adult stage,mating defective,flightless,flight defective,uncoordinated,neuroanatomy defective,visible" "wing vein,ectopic,mesothoracic tergum,photoreceptor,ommatidium,pupa,adult head,pupal cuticle,longitudinal muscle,bouton & abdominal 2 ventral longitudinal muscle 2,bouton & abdominal 3 ventral longitudinal muscle 2,bouton & abdominal 4 ventral longitudinal muscle 2,bouton & abdominal 5 ventral longitudinal muscle 2,bouton & abdominal 6 ventral longitudinal muscle 2,bouton & abdominal 7 ventral longitudinal muscle 2,chaeta" FBgn0087040 ë±Tub67C ë±-Tubulin at 67C http://flybase.net/reports/FBgn0087040.html "FBgn0001055, FBgn0004236, FBgn0001067, FBgn0003883" protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005525=GTP binding, 0003924=GTPase activity" "0051298=centrosome duplication, 0007017=microtubule-based process, 0000280=nuclear division, 0051258=protein polymerization, 0040016=embryonic cleavage, 0035044=sperm aster formation, 0051028=mRNA transport, 0035038=female pronucleus assembly, 0009792=embryo development ending in birth or egg hatching, 0007052=mitotic spindle organization, 0007422=peripheral nervous system development, 0035046=pronuclear migration, 0007417=central nervous system development, 0022008=neurogenesis" "0005737=cytoplasm, 0055028=cortical microtubule, 0005874=microtubule, 0048471=perinuclear region of cytoplasm, 0045298=tubulin complex, 0005634=nucleus, 0005886=plasma membrane" "alphatub67C, Kavar, Fs(3)Sz14, alpha4t, Tub, alpha67C, T, tubulin, alphaTUB, Fs(3)Kav, alpha4-tubulin, Female sterile (3) Kavar, alpha4, tub, alphaTub67C, kavar, alphatub, Fs(3)Tomaj, alpha-Tubulin, alpha tubulin, alphaTub 67C, alpha-Tub, tub67c, Tomaj, alphaTub, alphaT, alpha-tub67C, alpha-tubulin, aTub67C, tubulin67C, alpha4Tub67C, alphaTub4, Fs(3)Tom, gamma-Tub, alpha-tub, alphaTub[67C], alpha4-t, alpha tubulin 67C, alpha-Tub67C, Tubulin at 67C, 4t, mum-tub67C, D.m.ALPHA-67C, alpha Tubulin 67C, Tom, Fs(3)Sz22, alphaTubulin 67C, Fs(3)Kavar, alphatubulin, ALPHA 67C, alphaTubulin67C, alpha-tubulin[4], DTA2, CG8308" "IPR002452=Alpha tubulin, IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR000217=Tubulin, IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal" CG8308 16-Dec-15 2015_12 " adult stage && oogenesis stage | stage >=S10B , adult stage , embryonic stage | 0-2 hr , adult stage && oogenesis stage | stage <=S10B , adult stage && oogenesis stage , larval stage , embryonic stage | 0-12 hr , embryonic stage | stage 1-4 , embryonic stage | early , pupal stage , adult stage && oogenesis stage | stage >=S1 " " oocyte

, nurse cell

, ovary

, egg chamber

" " embryonic stage | early , embryonic stage | stage 13 , embryonic stage , adult stage && oogenesis stage , embryonic stage | 10 hr , egg stage | unfertilized egg " " longitudinal connective

, ovary

, ventral nerve cord commissure

, ventral midline

, unfertilized egg

, embryonic central nervous system

" DRSC11321 IE 2.115505178 -1.773754176 3.463222012 -1.082995485 -0.30730508 -0.549388021 FBgn0013753 Bgb Big brother http://flybase.net/reports/FBgn0013753.html protein_coding_gene "0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0003713=transcription coactivator activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0035206=regulation of hemocyte proliferation, 0045944=positive regulation of transcription from RNA polymerase II promoter" "0016513=core-binding factor complex, 0005634=nucleus" "rpbeta2, runt domain partner beta2, en(lz)D/9, Big-brother, bgb, CG7959, Big Brother" "IPR003417=Core binding factor, beta subunit" CG7959 16-Dec-15 2015_12 ENSDARG00000040917(cbfb) ENSXETG00000020027(CBFB) ENSMUSG00000031885(Cbfb) ENSG00000067955(CBFB) " embryonic stage , embryonic stage | stage >=13 " "

ubiquitous , embryonic central nervous system

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" abdominal vch1 neuron FBgn0004863 C15 C15 http://flybase.net/reports/FBgn0004863.html "FBgn0002943, FBgn0008640, FBgn0010393" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0022416=chaeta development, 0035015=elongation of arista core, 0007501=mesodermal cell fate specification, 0045747=positive regulation of Notch signaling pathway, 0007480=imaginal disc-derived leg morphogenesis, 0045892=negative regulation of transcription, DNA-templated, 0048800=antennal morphogenesis, 0051726=regulation of cell cycle, 0006355=regulation of transcription, DNA-templated, 0035218=leg disc development, 0045893=positive regulation of transcription, DNA-templated" "0005634=nucleus, 0043234=protein complex" "93Bal, 311, c15, clawless, cll, Cll, CG7937, Hox11-311, Ect5" "IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG7937 16-Dec-15 2015_12 "ENSDARG00000017615(tlx3b),ENSDARG00000006503,ENSDARG00000011273(tlx2),ENSDARG00000003965(tlx1)" WBGene00000442(ceh-19) "ENSXETG00000018304(tlx3),ENSXETG00000008043(TLX1),ENSXETG00000017822(TLX2)" "ENSMUSG00000040610(Tlx3),ENSMUSG00000025215(Tlx1),ENSMUSG00000068327(Tlx2)" "ENSG00000164438(TLX3),ENSG00000107807(TLX1),ENSG00000115297(TLX2)" " larval stage | late , pupal stage | early , embryonic stage | cellular blastoderm , embryonic stage | 4-24hr " dorsal ectoderm anlage | restricted

"lethal,some die during immature adult stage,recessive,partially,viable" "arista,unguis,tarsal segment 4,pulvillus,empodium,pretarsus,mesothoracic bristle,ocellar bristle" DRSC13495 K 1.046389853 -0.419385742 -0.579551324 0.199508799 -0.410530514 -1.878787893 FBgn0030093 Bap111 Brahma associated protein 111kD http://flybase.net/reports/FBgn0030093.html "FBgn0024493, FBgn0025971, FBgn0028547" protein_coding_gene "0005515=protein binding, 0003713=transcription coactivator activity, 0003677=DNA binding" "0043044=ATP-dependent chromatin remodeling, 0006338=chromatin remodeling, 0045893=positive regulation of transcription, DNA-templated" "0035060=brahma complex, 0016514=SWI/SNF complex, 0070604=PBAF complex, 0005634=nucleus" "anon-EST:Liang-1.83, BAP 111, Brahma associated protein 111kD, BAP111, CG7055, BAF57, Dalao, unnamed, clone 1.83, BRM-associated protein 111, Bap111, dalao" "IPR009071=High mobility group box domain, IPR030089=SWI/SNF complex subunit BAF57" CG7055 16-Dec-15 2015_12 ENSDARG00000016871(smarce1) "viable,fertile,lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" DRSC18419 E -1.202774072 -0.115092816 -1.580244651 0.943217708 0.5414767 -0.9141211 FBgn0038627 CG7694 http://flybase.net/reports/FBgn0038627.html FBgn0064910 protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0051865=protein autoubiquitination BcDNA:LP11469 "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type" CG7694 16-Dec-15 2015_12 ENSDARG00000023958(rnf181) ENSXETG00000001266(TEgg007l03.1) ENSMUSG00000055850(Rnf181) ENSG00000168894(RNF181) "viable,fertile" DRSC16288 E -0.103254096 -0.489509088 -1.570453504 0.248034514 0.483892792 0.983302956 FBgn0030584 CG14407 http://flybase.net/reports/FBgn0030584.html FBgn0063666 protein_coding_gene "0009055=electron carrier activity, 0015035=protein disulfide oxidoreductase activity" 0045454=cell redox homeostasis "Grx5, BcDNA:RH03087" "IPR012336=Thioredoxin-like fold, IPR004480=Monothiol glutaredoxin-related, IPR002109=Glutaredoxin" CG14407 16-Dec-15 2015_12 ENSDARG00000043665(glrx5) YPL059W(GRX5) WBGene00013029(glrx-5) ENSXETG00000025901(c14orf87) ENSMUSG00000021102(Glrx5) ENSG00000182512(GLRX5) "viable,visible" tormogen cell DRSC19593 K 0.426901158 1.084434679 0.389040598 -0.033652491 -0.270485987 1.618495604 FBgn0011556 ë¦Try ë¦Trypsin http://flybase.net/reports/FBgn0011556.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis 0005576=extracellular region "DmZetaTry, CG12387, zetaTry, SP110" "IPR009003=Peptidase S1, PA clan, IPR018114=Peptidase S1, trypsin family, active site, IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type" CG12387 16-Dec-15 2015_12 viable DRSC07720 K -0.669007 0.609929679 -0.293252833 -0.014790772 1.998710348 1.848528767 FBgn0039613 CG14527 http://flybase.net/reports/FBgn0039613.html protein_coding_gene 0004222=metalloendopeptidase activity 0006508=proteolysis "IPR018497=Peptidase M13, C-terminal domain, IPR008753=Peptidase M13, N-terminal domain, IPR000718=Peptidase M13, IPR024079=Metallopeptidase, catalytic domain" CG14527 16-Dec-15 2015_12 DRSC14878 K -0.264941403 0.004509544 -0.453878995 0.657443327 -0.247967355 1.709492447 FBgn0002773 Mlc2 Myosin light chain 2 http://flybase.net/reports/FBgn0002773.html protein_coding_gene "0005509=calcium ion binding, 0000146=microfilament motor activity" "0030239=myofibril assembly, 0003012=muscle system process, 0060361=flight" "0005859=muscle myosin complex, 0016459=myosin complex, 0030016=myofibril" "mlc-2, Myosin Regulatory Light Chain, MLC 2, mlc2, myosin light-chain 2, Myosin Light Chain-2, Dmlc2, CG2184, MRLC, RLC2, myosin regulatory light chain, MLC, Myosin LC2, RLC, myosin light chain-2, l(3)99Eb, dro MLC-2, Dmlc, MLC-2, LC2, MLC2, myosin light chain 2, muscle-specific myosin regulatory light chain, MYL2, Myosin alkali light chain 2, DmMLC2, Ifm(3)99Eb" "IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR002048=EF-hand domain" CG2184 16-Dec-15 2015_12 "wild-type,viable,flightless,female fertile,male fertile,flight defective,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "sarcomere, with Mlc2E38,indirect flight muscle & myofibril,indirect flight muscle & striated muscle thick filament,indirect flight muscle & striated muscle thin filament,indirect flight muscle & Z disc,sarcomere,sarcomere, with Mlc2S66A,S67A,sarcomere, with Mlc2ëÓ2-46" DRSC28878 K 0.096548434 -0.255454365 0.451642371 0.449442111 0.092077847 1.592682391 FBgn0032639 CG18563 http://flybase.net/reports/FBgn0032639.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SPH156 "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG18563 16-Dec-15 2015_12 viable DRSC02676 E -0.400086816 -0.199980305 2.17651789 -0.151481979 -0.56555944 0.481865279 FBgn0003866 tsh teashirt http://flybase.net/reports/FBgn0003866.html "FBgn0000058, FBgn0010570, FBgn0013543" protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" "0007384=specification of segmental identity, thorax, 0007476=imaginal disc-derived wing morphogenesis, 0007450=dorsal/ventral pattern formation, imaginal disc, 0048730=epidermis morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007479=leg disc proximal/distal pattern formation, 0048749=compound eye development, 0007494=midgut development, 0008258=head involution, 0007431=salivary gland development, 0061330=Malpighian tubule stellate cell differentiation, 0007480=imaginal disc-derived leg morphogenesis, 0035292=specification of segmental identity, trunk, 0007385=specification of segmental identity, abdomen, 0006357=regulation of transcription from RNA polymerase II promoter, 0007380=specification of segmental identity, head, 0045705=negative regulation of salivary gland boundary specification, 0035214=eye-antennal disc development, 0007473=wing disc proximal/distal pattern formation" 0005634=nucleus "l(2)B4-2-12, CG1374, T shirt, T-shirt, Tsh, Teashirt, aeroplane, l(2)04319, ae, ae[l]" "IPR007087=Zinc finger, C2H2, IPR027008=Teashirt family, IPR026807=Protein tiptop/teashirt, IPR015880=Zinc finger, C2H2-like" CG1374 16-Dec-15 2015_12 "ENSDARG00000015959,ENSDARG00000005026(tshz1)" "ENSXETG00000017555(TSHZ2),ENSXETG00000016288(TSHZ3)" "ENSMUSG00000047907,ENSMUSG00000046982(Tshz1),ENSMUSG00000021217(Tshz3)" "ENSG00000121297(TSHZ3),ENSG00000179981(TSHZ1),ENSG00000182463(TSHZ2)" " embryonic stage , embryonic stage | stage 13 , embryonic stage | extended germ band , embryonic stage | embryonic cycle 14A , embryonic stage | contracted germ band stage , embryonic stage | blastoderm " " epidermis &&of parasegment 3--13

, head

{ + Ubxhs.P } ,

{ v Antp* } , prothoracic segment | posterior

{ - Scr*, BX-C- } , somatic mesoderm

, mesothoracic segment

, metathoracic segment | posterior

{ - Scr*, BX-C- } , embryonic/larval pharynx

, parasegment 6

{ ^ BX-C- } , labial segment

{ + Antphs.PHTA } , head

,

{ 0 Dfd* } ,

45-60% egg length , abdominal segment 1--8

, embryonic central nervous system

, midgut constriction 2

, visceral mesoderm

, abdominal segment 1..8 | posterior

{ + salm* } , larval anus

, mesothoracic segment | posterior

{ - Scr*, BX-C- } ,

{ 0 lab* } , parasegment 6..13

{ - Scr*, BX-C- } , parasegment 2..13 embryonic central nervous system

{ 0 Scr* } , parasegment 4,5

{ ^ Ubx* } , parasegment 3--13

, parasegment 2,14,15

{ + salm* } " " embryonic stage | stage 15 , larval stage | third instar , embryonic stage | stage 8 , larval stage | second instar " " embryonic Malpighian tubule | restricted

, dorsal mesothoracic disc

, parasegment 3--14

" "visible,recessive,viable,lethal,mitotic cell cycle defective,dominant,heat sensitive,homeotic,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,flightless,some die during pupal stage,partially lethal,short lived,planar polarity defective,segment polarity phenotype,large body,developmental rate defective,lethal - all die before end of pupal stage,cell shape defective" "eye,ectopic,antennal disc,somatic clone,ventral,wing hinge,wing sclerite,haltere sclerite,vertical cleft,wing,haltere,leg,trochanter,coxa,femur,prothoracic coxal sensillum trichodeum,mesothoracic coxal sensillum trichodeum,metathoracic coxal sensillum trichodeum,prothoracic coxal bristle on hairy island,mesothoracic coxal bristle on hairy island,anterior scutellar bristle,Keilin's organ,mitotic cell cycle,wing vein,wing margin,maxillary palpus,adult head,arista,head & eye | ectopic,antenna & eye | ectopic,procephalic segment,heat sensitive,maxillary segment,labial segment,denticle belt,midgut constriction 1,midgut constriction 2,prothoracic segment,embryonic/larval cuticle,denticle row 1,denticle row 2,denticle row 3,denticle row 4,embryonic/first instar larval cuticle,embryonic prothoracic segment,embryonic labial segment,dorsal,larval abdomen,larval thorax,larval mesothoracic segment,larval abdominal segment 1,denticle row 5,supernumerary,proximal,metaphase & condensed nuclear chromosome,mitotic anaphase,mitotic metaphase,adult Malpighian tubule,adult abdomen,adult Malpighian tubule Type II cell,mouthpart,denticle belt & embryonic prothoracic segment,abdomen,eye-antennal disc,wing disc,eye disc,photoreceptor cell,antenna,denticle,embryonic head,T1 beard,embryonic maxillary segment,embryonic antennal segment,larval labial segment,larval maxillary segment & denticle | ectopic69B,larval antennal segment & denticle | ectopic69B,dorsal closure embryo,larval head,leg & cuticle | ventral | somatic clone,leg & cuticle | dorsal | somatic clone,leg & cuticle | somatic clone,tibia,prothoracic femoral bract,mesothoracic femoral bract,metathoracic femoral bract,ventral thoracic disc,leg & cuticle | ventral | somatic clonearm.THsimVP16,leg & cuticle | dorsal | somatic clonearm.THsimVP16,leg & cuticle | somatic clonearm.THsimVP16,cuprophilic cell,interommatidial bristle,eye photoreceptor cell,ectopic | third instar larval stage,dorsal compartment" FBgn0004828 His3.3B Histone H3.3B http://flybase.net/reports/FBgn0004828.html "FBgn0025266, FBtr0071345, FBpp0071280, FBtr0071346, FBpp0071281, FBtr0071347, FBpp0071282" protein_coding_gene "0046982=protein heterodimerization activity, 0003677=DNA binding" "0007140=male meiosis, 0006333=chromatin assembly or disassembly" 0000786=nucleosome "H3.3B, His 3.3B, anon-fast-evolving-1B6, CG8989, dH3.3B, Histone H3-3Q, histone variant 3.3, PH3, HistoneH3, His3.3, histone H3.3, anon-EST:fe1B6, H3.3, HisH3-3Q, histone variant H3.3" "IPR009072=Histone-fold, IPR007125=Histone H2A/H2B/H3, IPR000164=Histone H3/CENP-A" CG8989 16-Dec-15 2015_12 "ENSDARG00000033009(h3f3c),ENSDARG00000020504(h3f3a),ENSDARG00000068436(LOC100331798),ENSDARG00000045248(zgc:56418),ENSDARG00000068434(zgc:110292)" "YBR010W(HHT1),YNL031C(HHT2)" WBGene00001945(his-71) "ENSXETG00000012575(TGas113e22.1),ENSXETG00000022641(TGas113e22.1),ENSXETG00000027927(TGas113e22.1)" "ENSMUSG00000016559(H3f3b),ENSMUSG00000060743(H3f3a)" "ENSG00000196285,ENSG00000163041(H3F3A),ENSG00000132475(H3F3B)" " adult stage | female , oogenesis stage && adult stage | female , embryonic stage , spermatogenesis && adult stage , adult stage | male " " ovary

, testis

" " spermatogenesis && adult stage , larval stage " " spermatid

, larval salivary gland

, Y chromosome loop

, spermatocyte

, protein body

" viable DRSC18673 I -0.584147781 -2.117266808 -0.734575842 -0.450716052 0.147359308 0.055199479 FBgn0029094 asf1 anti-silencing factor 1 http://flybase.net/reports/FBgn0029094.html protein_coding_gene "0005515=protein binding, 0001103=RNA polymerase II repressing transcription factor binding" "0006334=nucleosome assembly, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0048813=dendrite morphogenesis, 0006325=chromatin organization, 0048024=regulation of mRNA splicing, via spliceosome, 0045746=negative regulation of Notch signaling pathway, 0007517=muscle organ development" "0005700=polytene chromosome, 0033186=CAF-1 complex, 0017053=transcriptional repressor complex, 0035059=RCAF complex" "anti-silencing factor, dAsf1, dASF1, CG9383, ASF1, Asf1, dASF/SF2, anti- silencing function 1, l(3)76BDq" "IPR006818=Histone chaperone, ASF1-like" CG9383 16-Dec-15 2015_12 "ENSDARG00000043713(asf1bb),ENSDARG00000020435(asf1ba),ENSDARG00000070967" YJL115W(ASF1) "WBGene00006817(unc-85),WBGene00007277(asfl-1)" "ENSXETG00000028029(asf1b),ENSXETG00000025074(ASF1A)" "ENSMUSG00000019857(Asf1a),ENSMUSG00000005470(Asf1b)" ENSG00000105011(ASF1B) embryonic stage -- adult stage "lethal,recessive,suppressor of variegation,dominant,lethal - all die before end of larval stage,some die during larval stage,female sterile,germline clone,visible,heat sensitive,viable" "ovary,germline clone,eye,larval salivary gland & nucleushs.2sev,macrochaeta,embryonic/larval salivary gland,trichogen cell" DRSC24067 IK 0.760593263 -2.154179605 -0.053583318 -0.77273666 -1.54696121 -0.745990721 FBgn0002941 slou slouch http://flybase.net/reports/FBgn0002941.html FBgn0004442 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0007517=muscle organ development, 0007501=mesodermal cell fate specification, 0007525=somatic muscle development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0007521=muscle cell fate determination, 0007399=nervous system development" 0005634=nucleus "paired-like 9, S59/NK-1, PRD gene 9, prd9, CG6534, Slou, Slouch, S59, NK1/S59, s59, NK-1, Nk1, NK1, slou/NK1, S-59" "IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG6534 16-Dec-15 2015_12 ENSMUSG00000036144(Meox2) "ENSG00000106511(MEOX2),ENSG00000005102(MEOX1)" embryonic stage | early embryonic stage " ganglion mother cell

, abdominal 2--7 ventral transverse muscle 1

, abdominal 1 ventral acute muscle 2

, abdominal 1 dorsal transverse muscle 1

, somatic mesoderm | restricted

, larval muscle system | restricted

, supraesophageal ganglion | restricted

, embryonic/larval midgut | restricted

, embryonic central nervous system

, abdominal 2--7 dorsal transverse muscle 1

, abdominal 2--7 ventral acute muscle 2

" "lethal,recessive,flight defective,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "presumptive embryonic/larval muscle system,abdominal 2 ventral transverse muscle 1,abdominal 3 ventral transverse muscle 1,abdominal 4 ventral transverse muscle 1,abdominal 5 ventral transverse muscle 1,abdominal 6 ventral transverse muscle 1,abdominal 7 ventral transverse muscle 1,abdominal 2 dorsal transverse muscle 1,abdominal 3 dorsal transverse muscle 1,abdominal 4 dorsal transverse muscle 1,abdominal 5 dorsal transverse muscle 1,abdominal 6 dorsal transverse muscle 1,abdominal 7 dorsal transverse muscle 1,A2-7 ventral transverse muscle 1,A1-7 ventral acute muscle 3,A1-7 ventral acute muscle 1,A1-7 ventral acute muscle 2,A1-7 lateral oblique muscle 1,segment border muscle,A1-7 dorsal oblique muscle 3,A1-7 dorsal transverse muscle 1,embryonic/larval somatic muscle,ventral,abdominal lateral adult muscle precursor cell,abdominal ventral adult muscle precursor cell,wing,cardioblast,adult muscle precursor cell,embryonic/larval dorsal vessel" FBgn0011701 repo reversed polarity http://flybase.net/reports/FBgn0011701.html "FBgn0010814, FBgn0013744, FBgn0051240" protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0006357=regulation of transcription from RNA polymerase II promoter, 0050764=regulation of phagocytosis, 0010628=positive regulation of gene expression, 0006355=regulation of transcription, DNA-templated, 0010001=glial cell differentiation, 0007399=nervous system development, 0021782=glial cell development, 0007422=peripheral nervous system development, 0051124=synaptic growth at neuromuscular junction, 0050808=synapse organization" "0005634=nucleus, 0005737=cytoplasm" "reverse polarity, CG8045(CT24072), unnamed, Repo, Reversed polarity, CT24072, Antibody RK2, 3702, AbRK2, Reversed Polarity, CG31240, REPO, l(3)03702, rk2, RK2" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG31240 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage 9 " " glial cell

, glioblast

, interface glial cell

" " embryonic stage , larval stage | third instar , embryonic stage | stage 10-11 , embryonic stage | stage 9-11 " " bipolar dendrite neuron

, peripheral glial cell 1--3

, medial intersegmental nerve root glial cell

, larval optic stalk

, channel glial cell

, tritocerebrum && CNS glial cell | subset

, glial cell &&of central nervous system

, glial cell &&of ventral thoracic disc

, glial cell &&of eye-antennal disc

, peripheral glial cell

, embryonic peripheral nervous system

, support cell of the dorsal bipolar dendritic cell

, tritocerebral neuroblast | subset

, exit glial cell

, scolopidial ligament cell

, B subperineurial glial cell of abdomen

, glial cell &&of dorsal mesothoracic disc

, lateral intersegmental nerve root glial cell

, medial-most cell body glial cell

, protocerebrum && CNS glial cell | subset

, A subperineurial glial cell

, interface glial cell

, intersegmental nerve root glial cell

" "viable,neurophysiology defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "lamina anlage,lamina & neuron,lamina & glial cell,retina,retina & axon,ventral nerve cord,VUM1 neuron & axon,VUM2 neuron & axon,VUM3 neuron & axon,VUM4 neuron & axon,VUM5 neuron & axon,VUM6 neuron & axon,glial cell,medial-most cell body glial cell,embryonic/larval glial cell,intersegmental nerve branch ISNb of A1-7,longitudinal connective,interface glial cell,lateral cord glial cell,PNS glial cell,trichogen cell,mesothoracic tergum" FBgn0004870 bab1 bric a brac 1 http://flybase.net/reports/FBgn0004870.html "FBgn0035183, FBgn0061802" protein_coding_gene "0003677=DNA binding, 0003680=AT DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding" "0048070=regulation of developmental pigmentation, 0007548=sex differentiation, 0007455=eye-antennal disc morphogenesis, 0006355=regulation of transcription, DNA-templated, 0006351=transcription, DNA-templated, 0007480=imaginal disc-derived leg morphogenesis, 0048086=negative regulation of developmental pigmentation, 0048071=sex-specific pigmentation, 0008585=female gonad development, 0048092=negative regulation of male pigmentation, 0046660=female sex differentiation" 0005634=nucleus "BAB1, bric-a-brac 1, BAB, CG13910, bab-I, Bric-a-brac, bric a brac, Bric a brac1, BAB-1, bric a brac I, anon-WO0118547.639, CG9097, bab, Bric a brac 1, Bab1, bric-a-brac, Bric a brac" "IPR009057=Homeodomain-like, IPR007889=DNA binding HTH domain, Psq-type, IPR011333=POZ domain, IPR000210=BTB/POZ domain" CG9097 16-Dec-15 2015_12 "ENSDARG00000061110(zbtb44),ENSDARG00000070864(bcl6a)" ENSXETG00000000723(NACC2) ENSG00000160877(NACC1) " larval stage | third instar stage 2 , larval stage | third instar , prepupal stage " " ventral thoracic disc | restricted

, ventral thoracic disc | restricted

, ovary | restricted

, eye-antennal disc | restricted

" " prepupal stage | stage P1 , prepupal stage , larval stage | third instar , larval stage | third instar stage 2 " " ovary | restricted

, tarsal segment

, eye-antennal disc | restricted

, central nervous system | restricted

, male genital disc | restricted

, larval central nervous system | restricted

, ventral thoracic disc | restricted

, female genital disc | restricted

" "female sterile,recessive,visible,partially,body color defective,female,dominant,heat sensitive,partially lethal - majority die,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "metathoracic tarsal segment 2,metathoracic tarsal segment 3,metathoracic tarsal segment 4,metathoracic tarsal segment 5,sex comb,ectopic,basal cylinder,ovary,terminal filament,germarium,ovariole,abdominal tergite 6,female,abdominal tergite 7,abdominal tergite 5,leg,antenna,prothoracic tarsal segment 2,prothoracic tarsal segment 3,prothoracic tarsal segment 4,prothoracic tarsal segment 5,mesothoracic tarsal segment 2,mesothoracic tarsal segment 3,mesothoracic tarsal segment 4,mesothoracic tarsal segment 5,macrochaeta,tergite" FBgn0000084 AnxB10 Annexin B10 http://flybase.net/reports/FBgn0000084.html protein_coding_gene "0005509=calcium ion binding, 0005544=calcium-dependent phospholipid binding, 0003779=actin binding, 0005543=phospholipid binding" 0016020=membrane "Annx, Ann, Annexin X, AnnX, anxX, annexin, CG9579, ANXB10, annexin X, AnxB10" "IPR018502=Annexin repeat, IPR018252=Annexin repeat, conserved site, IPR001464=Annexin" CG9579 16-Dec-15 2015_12 " embryonic stage , adult stage " "viable,fertile" DRSC25182 K -0.285198964 0.143723332 1.375469101 0.511433235 -1.626364031 -0.749220534 FBgn0000541 E(bx) Enhancer of bithorax http://flybase.net/reports/FBgn0000541.html "FBgn0013553, FBgn0016686, FBgn0035116, FBgn0035117, FBgn0035118, FBgn0061199" protein_coding_gene "0008270=zinc ion binding, 0016922=ligand-dependent nuclear receptor binding, 0070577=lysine-acetylated histone binding, 0035064=methylated histone binding, 0070615=nucleosome-dependent ATPase activity, 0003677=DNA binding" "0042766=nucleosome mobilization, 0045747=positive regulation of Notch signaling pathway, 0046331=lateral inhibition, 0010468=regulation of gene expression, 0006334=nucleosome assembly, 0035076=ecdysone receptor-mediated signaling pathway, 0035073=pupariation, 0030097=hemopoiesis, 0046426=negative regulation of JAK-STAT cascade, 0045824=negative regulation of innate immune response, 0007095=mitotic G2 DNA damage checkpoint, 0048813=dendrite morphogenesis, 0006338=chromatin remodeling, 0006325=chromatin organization, 0048515=spermatid differentiation, 0006351=transcription, DNA-templated, 0006357=regulation of transcription from RNA polymerase II promoter" 0016589=NURF complex "NURF215, NuRF301, NURF-215, Ebx, CG7022, nucleosome remodeling factor, E(Bx), dNURF301, l(3)ry122, E(BX), NURF 215, CG32346, Nurf 301, NURF301, Nurf-215, CG17135, Nucleosome remodeling factor - 215kD, En-bx, NURF, l(3)122, p215, nurf301, p301, NURF-301, Nurf301, Nucleosome remodeling factor, CG32478, e(bx), CG10894, dNURF" "IPR028942=WHIM1 domain, IPR001965=Zinc finger, PHD-type, IPR018359=Bromodomain, conserved site, IPR004022=DDT domain, IPR001487=Bromodomain, IPR018500=DDT domain, subgroup, IPR019787=Zinc finger, PHD-finger, IPR011011=Zinc finger, FYVE/PHD-type, IPR018501=DDT domain superfamily, IPR019786=Zinc finger, PHD-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR017956=AT hook, DNA-binding motif" CG32346 16-Dec-15 2015_12 WBGene00009180(nurf-1) ENSMUSG00000040481(Bptf) ENSG00000171634(BPTF) "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,germline clone,maternal effect,tumorigenic,viable,visible" "melanotic mass,polytene chromosomeNurf301-3),polytene chromosome,hemocyte,supernumerary,polytene chromosome3643),embryonic/larval hemocyte,dendrite,polytene chromosomeNurf301-2),embryonic/larval brain,chaeta,mesothoracic tergum" DRSC08583 IK -2.071342701 -0.359274794 -0.098412755 0.526552019 1.896558313 0.7325247 FBgn0022724 Taf8 TBP-associated factor 8 http://flybase.net/reports/FBgn0022724.html FBgn0014200 protein_coding_gene "0005515=protein binding, 0046982=protein heterodimerization activity" "0006367=transcription initiation from RNA polymerase II promoter, 0009987=cellular process, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005669=transcription factor TFIID complex "CG7128, Prodos, TAF[[II]], pro, dmTAF8, l(1)16Fg, TBP-associated factor, prod, TAF8, prodos, TFIID, HL-VIII, pds, TAF" "IPR019473=Transcription factor TFIID, subunit 8, C-terminal, IPR009072=Histone-fold, IPR006565=Bromodomain associated domain" CG7128 16-Dec-15 2015_12 ENSDARG00000026806(taf8) WBGene00006390(taf-8) ENSXETG00000011845(tbn) ENSMUSG00000023980(Taf8) ENSG00000137413(TAF8) "viable,fertile,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,cell lethalcell lethal,somatic clone,visible,lethal - all die before end of pupal stage,some die during pupal stage" "third instar larva,mesothoracic tergum" DRSC20363 IK -1.739406467 0.489849821 -0.642661665 -0.483991124 0.683414644 2.620180346 FBgn0038049 CG5844 http://flybase.net/reports/FBgn0038049.html protein_coding_gene 0004165=dodecenoyl-CoA delta-isomerase activity "0008152=metabolic process, 0071456=cellular response to hypoxia, 0006909=phagocytosis" Enoyl-CoA hydratase "IPR001753=Crotonase superfamily, IPR029045=ClpP/crotonase-like domain" CG5844 16-Dec-15 2015_12 ENSDARG00000038876(zgc:101569) WBGene00001152(ech-3) "ENSXETG00000024634(),ENSXETG00000024633()" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein" DRSC15890 IEK -3.414130964 -4.647446683 -1.713021855 -6.921746308 -1.917433292 -0.541825762 FBgn0040078 pont pontin http://flybase.net/reports/FBgn0040078.html "FBgn0028192, FBgn0037803, FBgn0061742" protein_coding_gene "0008013=beta-catenin binding, 0003678=DNA helicase activity, 0043141=ATP-dependent 5'-3' DNA helicase activity, 0005524=ATP binding, 0017025=TBP-class protein binding" "0007095=mitotic G2 DNA damage checkpoint, 0043486=histone exchange, 0006338=chromatin remodeling, 0090307=mitotic spindle assembly, 0010628=positive regulation of gene expression, 0016573=histone acetylation" "0035060=brahma complex, 0005634=nucleus, 0005875=microtubule associated complex, 0031011=Ino80 complex, 0035267=NuA4 histone acetyltransferase complex" "PON, CG4003, dpon, 0229/05, Pont, l(3)S022905, anon-WO0118547.698, dpontin, Tip49, RUVBL1, dPon, dPontin, pon, Tip49/Pontin, PONT, Pontin" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027238=RuvB-like, IPR003593=AAA+ ATPase domain, IPR010339=TIP49, C-terminal" CG4003 16-Dec-15 2015_12 ENSDARG00000002591(ruvbl1) YDR190C(RVB1) WBGene00007784(ruvb-1) ENSXETG00000002064(ruvbl1) ENSMUSG00000030079(Ruvbl1) ENSG00000175792(RUVBL1) "lethal,recessive,developmental rate defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,visible" "wing,somatic clone" DRSC17029 IEK -2.690886924 -0.008929931 -0.774996728 -2.013769098 0.18591314 1.665425273 FBgn0039959 CG17514 http://flybase.net/reports/FBgn0039959.html FBan0017514 protein_coding_gene 0008494=translation activator activity "IPR000357=HEAT repeat, IPR021133=HEAT, type 2, IPR026827=Proteasome component ECM29/Translational activator GCN1, IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG17514 16-Dec-15 2015_12 ENSDARG00000058419(LOC100333058) YGL195W(GCN1) WBGene00021697(gcn-1) ENSXETG00000012193(GCN1L1) ENSMUSG00000041638(Gcn1l1) ENSG00000089154(GCN1L1) viable DRSC20865 IE 0.709733597 -1.791643878 3.384964252 0.170475714 0.217238826 -0.301330453 FBgn0000114 aret arrest http://flybase.net/reports/FBgn0000114.html "FBgn0015367, FBgn0045095, FBgn0045436, FBgn0051762, FBgn0063197" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0005515=protein binding, 0003730=mRNA 3'-UTR binding, 0003723=RNA binding" "0017148=negative regulation of translation, 0042078=germ-line stem cell division, 0046011=regulation of oskar mRNA translation, 0007286=spermatid development, 0030727=germarium-derived female germ-line cyst formation, 0006378=mRNA polyadenylation, 2000738=positive regulation of stem cell differentiation, 0036099=female germ-line stem cell maintenance, 0007281=germ cell development, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0002121=inter-male aggressive behavior, 0007476=imaginal disc-derived wing morphogenesis, 0014881=regulation of myofibril size, 0031536=positive regulation of exit from mitosis, 0048477=oogenesis, 0045214=sarcomere organization, 0007319=negative regulation of oskar mRNA translation" "0005634=nucleus, 0016604=nuclear body, 0005737=cytoplasm, 0043186=P granule, 0031965=nuclear membrane" "BcDNA:GM15173, Bruno, aret/bruno1, arrest/Bruno, NEST:bs34h11, bruno, CG31762, CG6319, bru, Dm Bru, ARET, NEST:bs01g04, Aret, Bru, ms(2)01284" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG31762 16-Dec-15 2015_12 "ENSDARG00000002131(celf2),ENSDARG00000005315(celf1)" "ENSXETG00000021992(CUGBP2),ENSXETG00000009044(cugbp1)" "ENSMUSG00000002107(Celf2),ENSMUSG00000005506(Celf1)" "ENSG00000048740(CELF2),ENSG00000149187(CELF1)" " adult stage | male , adult stage | female , oogenesis stage && adult stage | female , adult stage && oogenesis stage " " testis

, germarium region 2a

, nurse cell

, germarium

, oocyte

" adult stage && oogenesis stage " oocyte

, nurse cell

, germarium

" "semi-sterile,embryonic/larval segmentation phenotype,partially lethal - majority die,recessive,male sterile,behavior defective,visible,female sterile,lethal - all die before end of embryonic stage,dominant,maternal effect,partially,some die during embryonic stage,viable" "embryonic/larval cuticle,posterior,female germline cyst,embryo,dorsal appendage,embryonic abdominal segment,maternal effect,wing,embryonic/first instar larval cuticle,ovary,egg chamber,nurse cell,oocyte,ovariole,nurse cell fusome,nurse cell spectrosome,nurse cell ring canal,germ cell & egg chamber | supernumerary,germ cell & egg chamber,mitosis | ectopic | oogenesis stage S4,mitosis | ectopic,mitosis | oogenesis stage S4,germline clone,oogonial cell,ectopic,ring canal,chorion,micropyle,female germline stem cell,progressive,female germline stem cell | larval stage,germ cell & egg chamber | supernumeraryesc-P3-0),germ cell & egg chamberesc-P3-0)" DRSC01238 IEK -2.800126077 -6.276498211 -2.763887093 -5.981616053 0.482230002 5.447174761 FBgn0004573 5-HT7 5-hydroxytryptamine (serotonin) receptor 7 http://flybase.net/reports/FBgn0004573.html protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0004993=serotonin receptor activity, 0004952=dopamine neurotransmitter receptor activity" "0016545=male courtship behavior, veined wing vibration, 0007210=serotonin receptor signaling pathway, 0060179=male mating behavior, 0060180=female mating behavior, 0016543=male courtship behavior, orientation prior to leg tapping and wing vibration, 0007619=courtship behavior, 0016546=male courtship behavior, proboscis-mediated licking, 0007192=adenylate cyclase-activating serotonin receptor signaling pathway" "0016021=integral component of membrane, 0005886=plasma membrane, 0005887=integral component of plasma membrane" "5HT[[7Dro]], Serotonin receptor, 5HT-dro1, Serotonin receptor 7, 5-HTdro1, DRO1, 5HT-R1, 5-HT[[7]], 5-HT-dro1, 5htdror, 5-HT7Dro, 5-HT[7]Dro, 5-HT[[7Dro]], CG12073, Dm5HTdro1, 5-HT[[7]]Dro, 5HT7, 5HT-7, 5-HT-dro, 5HT-dro, 5-HT[[dro1]], Serotonin receptor 1" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR000929=Dopamine receptor family, IPR000276=G protein-coupled receptor, rhodopsin-like" CG12073 16-Dec-15 2015_12 WBGene00004780(ser-7) " embryonic stage | stage 16-17 , adult stage " " ventral midline

, adult head

" "courtship behavior defective,mating behavior defective,viable,fertile,short lived,starvation stress response defective" Malpighian tubule FBgn0024958 Irp-1A Iron regulatory protein 1A http://flybase.net/reports/FBgn0024958.html protein_coding_gene "0030350=iron-responsive element binding, 0003729=mRNA binding, 0003994=aconitate hydratase activity, 0005506=iron ion binding" "0007370=ventral furrow formation, 0006447=regulation of translational initiation by iron" "cAcon, c-Acon, cytoplasmic aconitase, Iron regulatory protein, IRP1, IRP, cACON, irp1A, cytosolic aconitase, C-Acon, CG4900, IRP-1A, IRP-1, c-aconitase, iron regulatory factor, IRF, dIRP" "IPR015934=Aconitase/2-methylisocitrate dehydratase, IPR000573=Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR015931=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR001030=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR006249=Aconitate/Iron-responsive element-binding protein 2, IPR015932=Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR018136=Aconitase family, 4Fe-4S cluster binding site, IPR015937=Aconitase/isopropylmalate dehydratase, IPR015928=Aconitase/3-isopropylmalate dehydratase, swivel" CG4900 16-Dec-15 2015_12 ENSDARG00000021466 WBGene00000040(aco-1) ENSXETG00000009184(ACO1) ENSMUSG00000028405(Aco1) ENSG00000122729(ACO1) embryonic stage

ubiquitous "lethal,viable" FBgn0036285 toe twin of eyg http://flybase.net/reports/FBgn0036285.html FBgn0046345 protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development" "0005634=nucleus, 0005667=transcription factor complex" "CG10704, anon-WO0172774.89, twin of eyegone, Toe" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001523=Paired domain, IPR001356=Homeobox domain" CG10704 16-Dec-15 2015_12 "WBGene00001204(egl-38),WBGene00003938(pax-2)" " larval stage | third instar , larval stage | third instar--prepupal stage " " eye disc | dorsal && morphogenetic furrow | anterior to

, eye disc | anterior

, antennal disc | central

" "planar polarity defective,viable" "scutellum,microchaeta,ectopic,macrochaeta & scutumMS248,scutum,macrochaeta & scutumMD-638" FBgn0003300 run runt http://flybase.net/reports/FBgn0003300.html "FBgn0019659, FBgn0019997, FBtr0077279, FBpp0076971" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0005524=ATP binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007540=sex determination, establishment of X:A ratio, 0006357=regulation of transcription from RNA polymerase II promoter, 0007419=ventral cord development, 0007400=neuroblast fate determination, 0045893=positive regulation of transcription, DNA-templated, 0007377=germ-band extension, 0007366=periodic partitioning by pair rule gene, 0048813=dendrite morphogenesis, 0045892=negative regulation of transcription, DNA-templated, 0007411=axon guidance, 0048592=eye morphogenesis" 0005634=nucleus "legless, lLB5, section 1, CG1849, LB5, RUN, Rnt, 2, AA33, l(1)AA33, run, l(1)LB9, Runt, l(1)B2/13.1, P235, runt, l(1)19Ea, Run, RUNT, leg, section 2, 1" "IPR008967=p53-like transcription factor, DNA-binding, IPR013524=Runt domain, IPR012346=p53/RUNT-type transcription factor, DNA-binding domain, IPR000040=Acute myeloid leukemia 1 protein (AML1)/Runt" CG1849 16-Dec-15 2015_12 WBGene00004393(rnt-1) " embryonic stage | embryonic cycle 14 , embryonic stage | stage 4-11 , embryonic stage | stage 4 , embryonic stage&&larval stage , embryonic stage | embryonic cycle 13 , embryonic stage , adult stage | female , embryonic stage | stage 7-11 " "

pair rule , embryonic head

, organism | 70-90% egg length

,

10-70% egg length , proctodeum | primordium

" " embryonic stage | stage 9-11 , embryonic stage | stage 9-10 , embryonic stage | stage 9,10 , embryonic stage , embryonic stage | stage >=7 , embryonic stage | stage 11 , embryonic stage | blastoderm , embryonic stage | stage >=11 " " procephalic neurogenic region | restricted

, ventral neurogenic region

, ganglion mother cell GMC4-2a

, neuroblast NB4-2

{ 0 wg- } , U neuron

,

segment polarity , neuroblast

, neuroblast NB5-3

{ 0 wg- } ,

pair rule , deuterocerebral neuroblast | subset

, neurectoderm | row 2/3

{ + wg- } , EL neuron

, neuroblast NB3-2

, embryonic head | resticted

, ganglion mother cell GMC3-2a

{ + wg- } , embryonic central nervous system

, embryonic peripheral nervous system

, neurectoderm | row 4

{ 0 wg- } , neuroblast NB5-3

{ + wg- } , ganglion mother cell

, protocerebral neuroblast | subset

" "neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,pair rule phenotype,heat sensitive,wild-type,cell polarity defective,male sterile,viable,visible,partially,somatic clone" "denticle belt,outer photoreceptor cell,embryonic epidermis,heat sensitive,embryonic maxillary segment,mesothoracic segment,cell autonomous,abdominal segment 1,abdominal segment 3,abdominal segment 5,abdominal segment 7,somatic clone,abdominal segment 6,metathoracic segment,embryonic/first instar larval cuticle,abdominal vch1 neuron,embryonic segment,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,salivary gland,longitudinal connective,EL neuron,extended germ band embryo,abdominal segment 2,abdominal segment 4,abdominal segment 8,abdominal segment 9,abdominal segment 10,abdominal segment 11,lamina plexus | third instar larval stage,ventral nerve cord,ommatidium,eye,cephalopharyngeal skeleton,germ band" FBgn0020497 emb embargoed http://flybase.net/reports/FBgn0020497.html FBgn0021807 protein_coding_gene "0008536=Ran GTPase binding, 0005515=protein binding, 0008565=protein transporter activity, 0005049=nuclear export signal receptor activity" "0006611=protein export from nucleus, 0007099=centriole replication, 1900037=regulation of cellular response to hypoxia, 0007275=multicellular organismal development, 0051168=nuclear export, 0015031=protein transport" "0005634=nucleus, 0031965=nuclear membrane, 0005643=nuclear pore" "dCRM1, CG13387, exportin-1, DCRM1, Emb, XPO1, XPO-1, Exportin-1, crm1, Embargoed, l(2)k16715, CRM1, Xpo1, Exportin, Crm1, exportin, Chromosomal region maintenance 1" "IPR014877=CRM1 C-terminal domain, IPR011989=Armadillo-like helical, IPR001494=Importin-beta, N-terminal domain, IPR013598=Exportin-1/Importin-beta-like, IPR016024=Armadillo-type fold" CG13387 16-Dec-15 2015_12 ENSDARG00000063229(xpo1) YGR218W(CRM1) WBGene00002078(xpo-1) ENSXETG00000002224(XPO1) ENSMUSG00000020290(Xpo1) ENSG00000082898(XPO1) embryonic stage " embryonic/larval midgut

, embryonic/larval somatic muscle

, embryonic/larval posterior spiracle

, ventral nerve cord

, embryonic brain

, embryonic/larval hindgut

,

ubiquitous " "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,stress response defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,partially lethal - majority die,some die during pupal stage" embryonic/larval tracheal system DRSC03528 I -0.451068959 1.878097167 0.320031123 -0.859883538 -0.279782875 0.33583141 FBgn0025700 CG5885 http://flybase.net/reports/FBgn0025700.html FBgn0032159 protein_coding_gene 0006613=cotranslational protein targeting to membrane "0005784=Sec61 translocon complex, 0016021=integral component of membrane, 0030176=integral component of endoplasmic reticulum membrane, 0005786=signal recognition particle, endoplasmic reticulum targeting, 0005811=lipid particle" "AI945207, CK01296, BEST:CK01296" "IPR009779=Translocon-associated, gamma subunit" CG5885 16-Dec-15 2015_12 ENSDARG00000014165(ssr3) WBGene00021420(trap-3) ENSXETG00000027723(ssr3) ENSMUSG00000027828(Ssr3) ENSG00000114850(SSR3) DRSC02910 E 1.320153552 0.340640512 1.779095734 -0.219277971 0.191617255 -0.701793886 FBgn0028374 Hug Hugin http://flybase.net/reports/FBgn0028374.html FBgn0038062 protein_coding_gene "0071855=neuropeptide receptor binding, 0005102=receptor binding, 0005165=neurotrophin receptor binding, 0008255=ecdysis-triggering hormone activity, 0005179=hormone activity, 0005184=neuropeptide hormone activity, 0016084=myostimulatory hormone activity" "0030536=larval feeding behavior, 0018990=ecdysis, chitin-based cuticle, 0007218=neuropeptide signaling pathway" 0005615=extracellular space "Hug-gamma, hugg, HUGgamma, HUGIN, hug-PK, pyrokinin, CG6371, Hugin-gamma, SVPFKPRLamide, hugin, Hugin, hug-2, hug gamma, PK-2, Drm-MT2, hug-gamma, Pyrokinin, Drm-PK-2, pyrokinin-2, hugin gamma, pyrokinin/PBAN-like, hug, hug-1, Hugin-pyrokinin, Hugin-PK-2, huggamma, HUG" CG6371 16-Dec-15 2015_12 "lethal,partially,small body,feeding behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable" second instar larva DRSC16969 K 0.19908292 0.413276546 -0.534208533 0.630509807 2.673961164 1.926553085 FBgn0052103 CG32103 http://flybase.net/reports/FBgn0052103.html "FBgn0036283, FBgn0036284" protein_coding_gene "0022857=transmembrane transporter activity, 0005509=calcium ion binding" "0006839=mitochondrial transport, 0055085=transmembrane transport, 0006810=transport" "0031966=mitochondrial membrane, 0005778=peroxisomal membrane, 0005743=mitochondrial inner membrane" "CG18022, CG4392" "IPR018247=EF-Hand 1, calcium-binding site, IPR002167=Graves disease carrier protein, IPR002067=Mitochondrial carrier protein, IPR018108=Mitochondrial substrate/solute carrier, IPR002048=EF-hand domain, IPR023395=Mitochondrial carrier domain, IPR011992=EF-hand domain pair" CG32103 16-Dec-15 2015_12 "ENSDARG00000035468(si:dkey-7o20.1),ENSDARG00000010572(slc25a25),ENSDARG00000024708(si:dkey-204f11.59),ENSDARG00000008568(zgc:92470),ENSDARG00000005690(LOC561939)" YNL083W(SAL1) WBGene00008924(F17E5.2) "ENSXETG00000024509(SLC25A23),ENSXETG00000007731(SLC25A25)" "ENSMUSG00000026819(Slc25a25),ENSMUSG00000046329(Slc25a23),ENSMUSG00000040322(Slc25a24)" "ENSG00000148339(SLC25A25),ENSG00000085491(SLC25A24)" viable DRSC10293 I 1.555558042 0.701393022 -0.725933318 0.466152263 -0.02119975 -0.134571573 FBgn0051867 CG31867 http://flybase.net/reports/FBgn0051867.html "FBgn0063617, FBgn0063771" protein_coding_gene "CG6275, BcDNA:AT02643" CG31867 16-Dec-15 2015_12 "viable,planar polarity defective,partially lethal - majority die,some die during pupal stage" DRSC03338 K -0.786339235 -0.630252753 -0.638950057 0.820413106 -0.433935584 1.918494093 FBgn0037387 CG1213 http://flybase.net/reports/FBgn0037387.html protein_coding_gene 0005355=glucose transmembrane transporter activity 0055085=transmembrane transport 0016021=integral component of membrane CT30783 "IPR020846=Major facilitator superfamily domain, IPR005829=Sugar transporter, conserved site, IPR003663=Sugar/inositol transporter, IPR005828=Major facilitator, sugar transporter-like" CG1213 16-Dec-15 2015_12 "YDL138W(RGT2),YDL194W(SNF3)" "viable,fertile" DRSC12191 I -1.565842805 -0.22975542 0.409357845 0.592876319 1.394030747 0.694593555 FBgn0086779 step steppke http://flybase.net/reports/FBgn0086779.html "FBgn0032960, FBgn0040518, FBgn0022057, FBgn0065842" protein_coding_gene "0042803=protein homodimerization activity, 0005086=ARF guanyl-nucleotide exchange factor activity" "0008586=imaginal disc-derived wing vein morphogenesis, 0001700=embryonic development via the syncytial blastoderm, 0016192=vesicle-mediated transport, 0040018=positive regulation of multicellular organism growth, 0032956=regulation of actin cytoskeleton organization, 0030100=regulation of endocytosis, 0000187=activation of MAPK activity, 0032012=regulation of ARF protein signal transduction, 0030155=regulation of cell adhesion" "0005886=plasma membrane, 0005802=trans-Golgi network, 0005829=cytosol" "CYH1, Grp1, l(2)SH0323, cytohesin/GRP1, GRP1/cytohesin 1, GPH, general receptor for phosphoinositides-1, lethal (2) SH0323, l(2)SH2 0323, General receptor for phosphoinositides 1, step, lethal (2) k08110, CG11633, GRP1, Step, stepk, l(2)k08110, CG11628, steppke, Steppke" "IPR023394=Sec7 domain, alpha orthogonal bundle, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR000904=Sec7 domain, IPR001849=Pleckstrin homology domain" CG11628 16-Dec-15 2015_12 "ENSDARG00000028800(LOC569358),ENSDARG00000021488(zgc:73134),ENSDARG00000005159,ENSDARG00000038011(cyth4a)" WBGene00001743(grp-1) "ENSXETG00000024063(CYTH3),ENSXETG00000024577(pscd1)" "ENSMUSG00000018001(Cyth3),ENSMUSG00000003269(Cyth2),ENSMUSG00000017132(Cyth1),ENSMUSG00000018008(Cyth4)" "ENSG00000108669(CYTH1),ENSG00000008256(CYTH3),ENSG00000105443(CYTH2),ENSG00000100055(CYTH4)" DRSC03694 I 0.258075219 -4.185826467 -0.523682562 0.74607651 1.192565058 1.025020391 FBgn0260653 serp serpentine http://flybase.net/reports/FBgn0260653.html "FBgn0052209, FBgn0036902, FBgn0036903, FBgn0084276" protein_coding_gene "0004099=chitin deacetylase activity, 0008061=chitin binding" "0007424=open tracheal system development, 0035159=regulation of tube length, open tracheal system, 0006030=chitin metabolic process, 0005975=carbohydrate metabolic process" "0005604=basement membrane, 0005770=late endosome, 0005615=extracellular space, 0005737=cytoplasm" "Serpentine, CG8748, CG8747, DmCDA1, CG32209, l(3)76BDk, Serp" "IPR011330=Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002172=Low-density lipoprotein (LDL) receptor class A repeat, IPR002557=Chitin binding domain, IPR023415=Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002509=NodB homology domain" CG32209 16-Dec-15 2015_12 DRSC11036 E 0.771510849 1.007442734 -0.144201215 1.597760301 0.926181987 -0.054183341 FBgn0032135 GlcAT-S GlcAT-S http://flybase.net/reports/FBgn0032135.html protein_coding_gene "0046987=N-acetyllactosamine beta-1,3-glucuronosyltransferase activity, 0015020=glucuronosyltransferase activity, 0046988=asioloorosomucoid beta-1,3-glucuronosyltransferase activity, 0046989=galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity, 0015018=galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity" "0006688=glycosphingolipid biosynthetic process, 0030166=proteoglycan biosynthetic process, 0009101=glycoprotein biosynthetic process" 0016020=membrane "CG3881, dGlcAT-BSI, DGlcAT-S, DmGlcAT-BSI" "IPR005027=Glycosyl transferase, family 43, IPR029044=Nucleotide-diphospho-sugar transferases" CG3881 16-Dec-15 2015_12 embryonic stage -- adult stage "viable,fertile" DRSC27771 K 0.432317573 -0.996885559 -0.896703137 0.406812834 0.825625583 2.487111237 FBgn0027091 Aats-cys Cysteinyl-tRNA synthetase http://flybase.net/reports/FBgn0027091.html FBgn0027536 protein_coding_gene "0004817=cysteine-tRNA ligase activity, 0000049=tRNA binding, 0005524=ATP binding" 0006423=cysteinyl-tRNA aminoacylation "0005737=cytoplasm, 0005829=cytosol" "BcDNA:LD21177, CysRS, cysteinyl-trna synthetase, CG8431, CRS" "IPR024909=Cysteinyl-tRNA synthetase/mycothiol ligase, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR015803=Cysteine-tRNA ligase" CG8431 16-Dec-15 2015_12 ENSDARG00000036164(cars) YNL247W() WBGene00000800(cars-1) ENSXETG00000021868(cars) ENSMUSG00000010755(Cars) ENSG00000110619(CARS) embryonic stage

ubiquitous "lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC05948 I -1.815978701 -0.158975055 0.412933527 -0.226250412 0.142410218 -0.920854791 FBgn0264491 how held out wings http://flybase.net/reports/FBgn0264491.html "FBgn0028068, FBgn0082187, FBgn0017397, FBgn0011379, FBgn0011385, FBgn0015249, FBgn0020779, FBgn0025731, FBgn0025956" protein_coding_gene "0003727=single-stranded RNA binding, 0003729=mRNA binding, 0003730=mRNA 3'-UTR binding" "0007498=mesoderm development, 0030718=germ-line stem cell maintenance, 0007521=muscle cell fate determination, 0006417=regulation of translation, 0007525=somatic muscle development, 0007284=spermatogonial cell division, 0030154=cell differentiation, 0007155=cell adhesion, 0008016=regulation of heart contraction, 0045214=sarcomere organization, 0045995=regulation of embryonic development, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0008366=axon ensheathment, 0008078=mesodermal cell migration, 0007517=muscle organ development, 0008347=glial cell migration, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0007438=oenocyte development" "0005737=cytoplasm, 0005634=nucleus" "stru, How, HOW, CG10293, l(3)S090417, Held-out wings, l(3)s2612, clone 2.39, l(3)j5B5, Held Out Wing, wings held out, wings held-out, qkr[93F], who, lethal (3) S053606, Who/How, 0904/17, sci, Held out wings, scorpion, KH motif at 93F, SZ1, struthio, P62, l(3)j5D5, l(3)S053606, KH93F, 24B, anon-EST:Liang-2.39, lethal (3) S090417, quaking related, 93F, qkr" "IPR031119=STAR-domain RNA-binding protein GLD-1/HOW, IPR004087=K Homology domain, IPR004088=K Homology domain, type 1" CG10293 16-Dec-15 2015_12 "ENSDARG00000010018(zgc:65890),ENSDARG00000002026,ENSDARG00000044462(qk)" WBGene00006423(asd-2) ENSXETG00000015705(QKI) ENSMUSG00000062078(Qk) ENSG00000112531(QKI) " embryonic stage | stage >=15 , embryonic stage | stage >=6 , embryonic stage , embryonic stage | stage 6 , embryonic stage | stage >=14 , embryonic stage -- adult stage , embryonic stage | early , adult stage | female , embryonic stage | stage 12 , embryonic stage | late , embryonic stage | stage 14 , embryonic stage | stage 6,7 , pupal stage , embryonic stage&&pupal stage " " embryonic/larval somatic muscle

, mesoderm

, mesoderm anlage

, ventral furrow

, muscle attachment site

, embryonic/larval heart

, visceral mesoderm

, pharyngeal muscle

, larval visceral muscle

, embryonic/larval dorsal vessel

, myoblast &&of larval muscle system

, embryonic/larval aorta

, somatic mesoderm

" " larval stage , embryonic stage | stage 14 , embryonic stage | stage >=14 , adult stage , embryonic stage | stage >7 , embryonic stage | stage >=15 , embryonic stage | stage 6,7 , embryonic stage | stage 6-7 , adult stage && oogenesis stage " " imaginal disc

, cardioblast

, muscle attachment site

, hindgut muscle

, mesoderm

, pharyngeal muscle

, embryonic/larval aorta

, cephalic furrow

, head mesoderm

, muscle fiber &&of larval muscle system

, ventral furrow

, adepithelial cell

, larval visceral muscle

, embryonic/larval somatic muscle

, mesoderm anlage

, interfollicle cell

, tendon cell

, embryonic/larval dorsal vessel

" DRSC25008 IEK -1.605999246 -2.809241145 -1.661924498 -1.561220948 0.708623265 4.482111321 FBgn0004862 bap bagpipe http://flybase.net/reports/FBgn0004862.html FBgn0002943 protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0007507=heart development, 0007494=midgut development, 0007498=mesoderm development, 0045165=cell fate commitment, 0007522=visceral muscle development, 0007501=mesodermal cell fate specification, 0006357=regulation of transcription from RNA polymerase II promoter, 0001710=mesodermal cell fate commitment" 0005634=nucleus "Bap, CG7902, nk-3, BAP, NK-3, bgp, Bagpipe, NK3, dNK-3" "IPR020479=Homeodomain, metazoa, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG7902 16-Dec-15 2015_12 ENSXETG00000023620(NKX1-1) ENSMUSG00000049691(Nkx3-2) " embryonic stage | stage >12 , embryonic stage | stage 11-15 , embryonic stage | stage 10-11 , embryonic stage " " cardioblast

, visceral mesoderm &&of embryonic/larval foregut

, visceral mesoderm &&of embryonic/larval midgut

, mesoderm | dorsal

, visceral mesoderm &&of embryonic/larval hindgut

" "wild-type,lethal" "midgut muscle,embryonic/larval midgut" FBgn0261854 aPKC atypical protein kinase C http://flybase.net/reports/FBgn0261854.html "FBgn0022131, FBgn0033986, FBgn0260478, FBgn0050475" protein_coding_gene "0005524=ATP binding, 0005515=protein binding, 0004674=protein serine/threonine kinase activity, 0004697=protein kinase C activity, 0017022=myosin binding" "0045186=zonula adherens assembly, 0045167=asymmetric protein localization involved in cell fate determination, 0007294=germarium-derived oocyte fate determination, 0035011=melanotic encapsulation of foreign target, 0030011=maintenance of cell polarity, 0007163=establishment or maintenance of cell polarity, 0000132=establishment of mitotic spindle orientation, 0001738=morphogenesis of a polarized epithelium, 0045176=apical protein localization, 0010592=positive regulation of lamellipodium assembly, 0002052=positive regulation of neuroblast proliferation, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0051601=exocyst localization, 0055059=asymmetric neuroblast division, 0007309=oocyte axis specification, 0046667=compound eye retinal cell programmed cell death, 0072659=protein localization to plasma membrane, 0045198=establishment of epithelial cell apical/basal polarity, 0035556=intracellular signal transduction, 0007314=oocyte anterior/posterior axis specification, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0006468=protein phosphorylation, 0051491=positive regulation of filopodium assembly, 0007416=synapse assembly, 0016334=establishment or maintenance of polarity of follicular epithelium, 0007043=cell-cell junction assembly, 0007423=sensory organ development, 0060446=branching involved in open tracheal system development, 0003382=epithelial cell morphogenesis, 0007283=spermatogenesis, 0045196=establishment or maintenance of neuroblast polarity, 0007613=memory, 0090163=establishment of epithelial cell planar polarity" "0016324=apical plasma membrane, 0005938=cell cortex, 0016327=apicolateral plasma membrane, 0035003=subapical complex, 0045179=apical cortex" "CG10261, pkc-3, Atypical Protein Kinase C, Atypical PKC, PKCl,i, dapkc, Atypical protein kinase C, pschur, atypical-Protein Kinase C, psu, a-PKC, atypical PKC, alphaPKCzeta, atypical protein kinase, apkc, PKCzeta, l(2)k06403, CG42783, aPkc, CG30475, aPKCzeta, DaPKC, atypical Protein kinase C, daPKC, atypical Protein Kinase C, aPKC-zeta" "IPR011009=Protein kinase-like domain, IPR020454=Diacylglycerol/phorbol-ester binding, IPR012233=Protein kinase C, IPR017892=Protein kinase, C-terminal, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal, IPR008271=Serine/threonine-protein kinase, active site, IPR000270=PB1 domain, IPR000719=Protein kinase domain" CG42783 16-Dec-15 2015_12 "ENSDARG00000021225(prkci),ENSDARG00000043332(prkcz)" WBGene00004034(pkc-3) ENSXETG00000009210(prkci) "ENSMUSG00000037643(Prkci),ENSMUSG00000029053(Prkcz)" "ENSG00000163558(PRKCI),ENSG00000067606(PRKCZ)" pupal stage photoreceptor cell stalk | apical

FBgn0011227 ox oxen http://flybase.net/reports/FBgn0011227.html "FBgn0024946, FBgn0026780, FBgn0047014" protein_coding_gene 0008121=ubiquinol-cytochrome-c reductase activity "0007286=spermatid development, 0006122=mitochondrial electron transport, ubiquinol to cytochrome c" 0005750=mitochondrial respiratory chain complex III "Qcr10, Ubiquinol-cytochrome C reductase complex 7.2 kDa protein, Ubiquinol-cytochrome C reductase, UCRX, Ubiquinol-cytochrome c reductase complex 7.2 kDa protein, Ubiquinol-cytochrome c reductase 7.2 kDa protein, BcDNA:RH44662, Qcr9, QCR9, UQCR-7.2, ms(2)00815, Ubiquinol-cytochrome c oxidoreductase 7.2 kDa, CG8764, unnamed" IPR008027=Cytochrome b-c1 complex subunit 9 CG8764 16-Dec-15 2015_12 YGR183C(QCR9) ENSXETG00000024784(TNeu126i07.1) ENSMUSG00000059534(Uqcr10) " embryonic stage | stage 5-11 , embryonic stage | stage 13 , embryonic stage | stage 13-17 " "

ubiquitous , amnioserosa

, embryonic/larval midgut

" "viable,fertile,male sterile,recessive,partially lethal - majority die,wild-type,lethal,cell lethalcell lethal,somatic clone,visible,some die during pupal stage" "oocyte,germline clone,trichogen cell" FBgn0004882 orb oo18 RNA-binding protein http://flybase.net/reports/FBgn0004882.html protein_coding_gene "0017131=uridine-rich cytoplasmic polyadenylylation element binding, 0005515=protein binding, 0003729=mRNA binding, 0000166=nucleotide binding" "0000578=embryonic axis specification, 0007310=oocyte dorsal/ventral axis specification, 0007314=oocyte anterior/posterior axis specification, 0007309=oocyte axis specification, 0007281=germ cell development, 0007315=pole plasm assembly, 0048477=oogenesis, 0007294=germarium-derived oocyte fate determination, 0048134=germ-line cyst formation, 0046011=regulation of oskar mRNA translation, 0045727=positive regulation of translation, 0046012=positive regulation of oskar mRNA translation, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0045451=pole plasm oskar mRNA localization, 0006378=mRNA polyadenylation, 0008298=intracellular mRNA localization" "0030529=ribonucleoprotein complex, 0005737=cytoplasm" "oo18, Oo18 RNA-binding protein, 151666_s_at, ORB, Oo18, oo18 RNA binding, CG10868, oo18 RNA-binding protein, fs(3)00107, Orb" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10868 16-Dec-15 2015_12 WBGene00000772(cpb-3) ENSXETG00000010660(CPEB1) ENSG00000214575(CPEB1) " larval stage | third instar , embryonic stage | stage 4-8 , spermatogenesis && adult stage , adult stage && oogenesis stage | stage S11-14 , pupal stage && adult stage , adult stage && oogenesis stage | stage S8-10 , adult stage && oogenesis stage | stage S1-6 , adult stage && oogenesis stage | stage S7 , larval stage--adult stage | male && spermatogenesis , embryonic stage | early " " pole cell

, spermatid

, oocyte | ubiquitous

, oocyte | anterior

, nurse cell

, testis

,

posterior , spermatocyte

" " adult stage && oogenesis stage | stage S8-10 , oogenesis stage | stage S8-10 " " nurse cell

, oocyte

" "female sterile,recessive,viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,sterile,dominant,partially,germline clone,lethal,partially lethal - majority die,visible,some die during pupal stage" "ovary,chorion | maternal effect,egg chamber,egg,oocyte,embryonic abdomen,dorsal appendage,chorion,chorion | maternal effect, with orb8E2Hd.Hsp83.TEcollacZ,synaptonemal complex | ectopic,germline cyst,maternal effect,dorsal,synaptonemal complex,embryo,posterior,chorion | maternal effect, with orbF343,trichogen cell,mesothoracic tergum" FBgn0004167 kst karst http://flybase.net/reports/FBgn0004167.html FBgn0010743 protein_coding_gene "0003779=actin binding, 0005515=protein binding, 0005543=phospholipid binding, 0008092=cytoskeletal protein binding, 0008017=microtubule binding" "0006897=endocytosis, 0010797=regulation of multivesicular body size involved in endosome transport, 0030707=ovarian follicle cell development, 0007009=plasma membrane organization, 0045186=zonula adherens assembly, 0042060=wound healing, 0032509=endosome transport via multivesicular body sorting pathway, 0000281=mitotic cytokinesis" "0016327=apicolateral plasma membrane, 0008091=spectrin, 0005912=adherens junction, 0016324=apical plasma membrane, 0032432=actin filament bundle, 0005886=plasma membrane" "beta[[H]]spectrin, betaH-Spectrin, Karst, beta[[H]]-Sp, beta[[Heavy]]spectrin, Spectrin, beta[[H]]-Spec, beta[[heavy]]spectrin, beta[[heavy]]-Spec, spectrin, Spec-beta[[H]], beta[[H]]-SPEC, betah-Spec, beta[[Heavy]]-spectrin, betaH, beta[[(HEAVY)]]-spectrin, l(3)01318, CG12008, beta-H spectrin, betaHeavy-Spectrin, betaheavy-spectrin, beta-heavy-spectrin, Kst, b[Heavy]-spectrin, Spectrin-beta[[H]], betaH-spectrin, Spectrin beta-heavy chain, betaHeavy--spectrin, beta[[H]]-Spectrin, beta[[heavy]]-Spectrin, betaHS, betaH-Spec, betaHeavy-spectrin, beta-Heavy spectrin, beta[[H]]-spectrin, beta[[Heavy]]-Spectrin, beta-Spectrin, beta[[H]], beta[[H]] spectrin" "IPR001715=Calponin homology domain, IPR001605=Pleckstrin homology domain, spectrin-type, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR018159=Spectrin/alpha-actinin, IPR001589=Actinin-type actin-binding domain, conserved site, IPR001849=Pleckstrin homology domain, IPR002017=Spectrin repeat, IPR001452=SH3 domain" CG12008 16-Dec-15 2015_12 WBGene00004855(sma-1) ENSG00000137877(SPTBN5) " adult stage && oogenesis stage | early , larval stage , adult stage | female && oogenesis stage | early , oogenesis stage && adult stage | female " " follicle cell

, salivary gland

, germline stem cell

" "partially lethal - majority die,recessive,viable,visible,lethal,lethal - all die before end of larval stage,some die during larval stage,sterile,partially" "embryonic/larval midgut,follicle cell,eye,macrochaeta,ectopic,rhabdomere,somatic clone,eye photoreceptor cell stalk,wing,ommatidium,photoreceptor cell R7,adult tracheal system,border follicle cell,oocyte,centripetally migrating follicle cell,nurse cell,wing & epithelial cell,embryonic/larval cuprophilic cell" FBgn0002638 Rcc1 Regulator of chromosome condensation 1 ortholog (H. sapiens) http://flybase.net/reports/FBgn0002638.html FBgn0041146 protein_coding_gene "0003682=chromatin binding, 0005087=Ran guanyl-nucleotide exchange factor activity" "0007346=regulation of mitotic cell cycle, 0006607=NLS-bearing protein import into nucleus, 0030261=chromosome condensation, 0046822=regulation of nucleocytoplasmic transport, 0050767=regulation of neurogenesis, 0007417=central nervous system development, 0007076=mitotic chromosome condensation, 0022008=neurogenesis" "0000793=condensed chromosome, 0005634=nucleus, 0005737=cytoplasm" "Bj1, RanGEF, CG10480, inxs, RCC1, CG18640 (Bj1), regulator of chromosome condensation 1, in excess, Bj1 protein, sdt, Rcc1, CG18640 (Bj1), RCC protein, BJ1, side-out, dRCC1" "IPR000408=Regulator of chromosome condensation, RCC1, IPR009091=Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG10480 16-Dec-15 2015_12 ENSDARG00000037158(rcc1) YGL097W(SRM1) WBGene00004304(ran-3) ENSXETG00000012969(rcc1) ENSMUSG00000028896(Rcc1) ENSG00000180198(RCC1) " embryonic stage | early , adult stage && oogenesis stage , embryonic stage " " nurse cell

, neuroblast

, oocyte

" " embryonic stage , adult stage && oogenesis stage , larval stage " " embryonic central nervous system

, neuroblast

, oocyte

, embryonic/larval salivary gland

, nurse cell

" "lethal,germline clone,cell lethalcell lethal,somatic clone,viable,fertile,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "EL neuron,central nervous system,lateral,eye,eye photoreceptor cell,ommatidium,anterior fascicle & synapse,intersegmental nerve,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0004574 Rop Ras opposite http://flybase.net/reports/FBgn0004574.html FBgn0014289 protein_coding_gene "0000149=SNARE binding, 0019905=syntaxin binding" "0006887=exocytosis, 0048489=synaptic vesicle transport, 0016192=vesicle-mediated transport, 0007317=regulation of pole plasm oskar mRNA localization, 0009416=response to light stimulus, 0016082=synaptic vesicle priming, 0007268=synaptic transmission, 0006904=vesicle docking involved in exocytosis, 0000281=mitotic cytokinesis, 0032940=secretion by cell, 0007269=neurotransmitter secretion" "0016020=membrane, 0043195=terminal bouton, 0012506=vesicle membrane, 0005737=cytoplasm, 0005829=cytosol, 0019898=extrinsic component of membrane" "rop(Sec1), ras opposite, SEC1, l(3)64Ah, cs1, rop, ROP, CG15811, l(3)SH16, ras2" "IPR027482=Sec1-like, domain 2, IPR001619=Sec1-like protein" CG15811 16-Dec-15 2015_12 "ENSDARG00000001994(stxbp1),ENSDARG00000056036(si:rp71-10d23.3)" YDR164C(SEC1) WBGene00006757(unc-18) ENSXETG00000014261(STXBP1) ENSMUSG00000026797(Stxbp1) ENSG00000136854(STXBP1) embryonic stage " central nervous system

, garland cell

, embryonic peripheral nervous system

, antenno-maxillary complex

" " embryonic stage | stage >=13 , embryonic stage | stage >=16 , embryonic stage | stage >=14 , larval stage | third instar , embryonic stage " " epidermis

, segmental nerve

, Malpighian tubule

, Bolwig's nerve

, intersegmental nerve

, larval muscle system

, neuropil

, embryonic/larval digestive system

, embryonic central nervous system

, embryonic/larval salivary gland

, imaginal disc

, garland cell

, bouton

" "lethal,recessive,neurophysiology defective,heat sensitive,partially lethal - majority die,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage" "central nervous system,egg,germline clone,oocyte,embryonic/first instar larval cuticle,tracheal branch primordium" FBgn0034900 CG12491 http://flybase.net/reports/FBgn0034900.html protein_coding_gene CG12491 16-Dec-15 2015_12 DRSC26465 K 0.136071702 0.771067704 0.78880305 0.056185984 -0.34816548 -1.643721387 FBgn0030556 mRNA-cap mRNA-capping-enzyme http://flybase.net/reports/FBgn0030556.html protein_coding_gene "0008138=protein tyrosine/serine/threonine phosphatase activity, 0004484=mRNA guanylyltransferase activity, 0004725=protein tyrosine phosphatase activity, 0004651=polynucleotide 5'-phosphatase activity" "0006470=protein dephosphorylation, 0006370=7-methylguanosine mRNA capping" 0005634=nucleus "CG1810, PIR, mRNA-capping-enzyme, mRNA capping enzyme" "IPR029021=Protein-tyrosine phosphatase-like, IPR001339=mRNA capping enzyme, catalytic domain, IPR012340=Nucleic acid-binding, OB-fold, IPR000387=Tyrosine specific protein phosphatases domain, IPR000340=Dual specificity phosphatase, catalytic domain, IPR017074=mRNA capping enzyme, bifunctional, IPR013846=mRNA capping enzyme, C-terminal, IPR016130=Protein-tyrosine phosphatase, active site" CG1810 16-Dec-15 2015_12 ENSDARG00000032261(rngtt) WBGene00000466(cel-1) ENSXETG00000005384(rngtt) ENSMUSG00000028274(Rngtt) ENSG00000111880(RNGTT) DRSC19789 I -1.681431998 2.632845594 -0.608769398 0.192762353 0.873918614 0.76231957 FBgn0085444 mute muscle wasted http://flybase.net/reports/FBgn0085444.html "FBgn0034170, FBgn0053455, FBgn0053456" protein_coding_gene 0003677=DNA binding "0046716=muscle cell cellular homeostasis, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" 0035363=histone locus body "CG33456, CG15610, Mute, muscle wasted, CG33455, CG34415, mute" "IPR003822=Paired amphipathic helix, IPR009057=Homeodomain-like" CG34415 16-Dec-15 2015_12 "ENSDARG00000005867(udu),ENSDARG00000056847(LOC100334444)" ENSMUSG00000054199 ENSG00000116580(GON4L) "lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,germline clone,recessive,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,ganglion mother cell" DRSC22931 IE -2.345544283 -1.312885613 -2.372607171 -3.272950903 0.703371717 0.405701852 FBgn0010198 RpS15Aa Ribosomal protein S15Aa http://flybase.net/reports/FBgn0010198.html "FBgn0025291, FBgn0030473" protein_coding_gene 0003735=structural constituent of ribosome "0007052=mitotic spindle organization, 0006412=translation, 0000022=mitotic spindle elongation" "0005840=ribosome, 0022627=cytosolic small ribosomal subunit" "S15Aa, RpS15a, anon-EST:Posey44, CG2033, S15, Ribosomal protein S15A, RpS15A, Rp S15 Aa" IPR000630=Ribosomal protein S8 CG2033 16-Dec-15 2015_12 ENSDARG00000010160(rps15a) "YLR367W(RPS22B),YJL190C(RPS22A)" WBGene00004491(rps-22) ENSXETG00000002942(RPS15A) "ENSMUSG00000008683(Rps15a),ENSMUSG00000067058(Gm10196),ENSMUSG00000067351" ENSG00000134419(RPS15A) "lethal,partially lethal - majority die,size defective" adult heart DRSC06129 EK -1.026518644 -0.756498897 1.519949629 -2.823516732 1.299159812 4.278623486 FBgn0011305 Rsf1 Repressor splicing factor 1 http://flybase.net/reports/FBgn0011305.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding" "0010468=regulation of gene expression, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0031440=regulation of mRNA 3'-end processing, 0048025=negative regulation of mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "ROX21, CG5655, RSF1, rox21, unnamed, Rox21" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG5655 16-Dec-15 2015_12 "visible,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "eye,retina,macrochaeta" DRSC21953 K -1.279895246 0.160715105 -0.792926664 -0.165171915 0.524180928 1.950456959 FBgn0037344 CG2926 http://flybase.net/reports/FBgn0037344.html protein_coding_gene 0008270=zinc ion binding "0000381=regulation of alternative mRNA splicing, via spliceosome" 0005634=nucleus "IPR019787=Zinc finger, PHD-finger, IPR019786=Zinc finger, PHD-type, conserved site, IPR011011=Zinc finger, FYVE/PHD-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR001841=Zinc finger, RING-type" CG2926 16-Dec-15 2015_12 ENSDARG00000045885 ENSXETG00000006032(PHRF1) ENSMUSG00000038611(Phrf1) ENSG00000070047(PHRF1) "viable,fertile,visible" "chaeta,supernumerary" DRSC12321 IE 0.058743841 -2.317297617 2.507399074 -0.476914823 0.170233085 0.130572461 FBgn0003048 pcx pecanex http://flybase.net/reports/FBgn0003048.html "FBgn0000752, FBgn0026853" protein_coding_gene "0007029=endoplasmic reticulum organization, 0046331=lateral inhibition, 0007219=Notch signaling pathway" "0005886=plasma membrane, 0005783=endoplasmic reticulum, 0016021=integral component of membrane, 0005887=integral component of plasma membrane" "fs(1)12-1012, mel(1)R, fs(1)12-4169, fs(1)A387, fs(1)12-2135, fs(1)12-1743, fs(1)pcx, fs(1)M10, CG3443, fs(1)14-1153, fs(1)12-3102, fs(1)14-567, EG:30B8.4, fs(1)12-3014, mel(1)R1, DMPCX" IPR007735=Pecanex CG3443 16-Dec-15 2015_12 "ENSDARG00000019501,ENSDARG00000011819(pcnx),ENSDARG00000055698(si:ch211-120p12.4)" WBGene00015237(B0511.12) ENSXETG00000021815(PCNX) "ENSMUSG00000021140(Pcnx),ENSMUSG00000054874(Pcnxl3)" ENSG00000100731(PCNX) "female sterile,recessive,wild-type,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,neurogenic phenotype,viable,visible" "egg,maternal effect,endoplasmic reticulum | maternal effect,presumptive embryonic/larval central nervous system,embryonic/first instar larval cuticle,ventral,chaeta,supernumerary" DRSC18190 I 1.504312556 -0.338309762 -0.521360591 0.241430014 0.016361419 -0.238104751 FBgn0025638 Roc1a Regulator of cullins 1a http://flybase.net/reports/FBgn0025638.html "FBgn0025527, FBgn0025705" protein_coding_gene "0008270=zinc ion binding, 0097602=cullin family protein binding, 0061630=ubiquitin protein ligase activity" "0006508=proteolysis, 0022008=neurogenesis, 0016322=neuron remodeling, 0008283=cell proliferation, 0019915=lipid storage, 0016567=protein ubiquitination, 0007224=smoothened signaling pathway, 0030178=negative regulation of Wnt signaling pathway" "0031462=Cul2-RING ubiquitin ligase complex, 0019005=SCF ubiquitin ligase complex, 0080008=Cul4-RING E3 ubiquitin ligase complex, 0031463=Cul3-RING ubiquitin ligase complex" "Roc1a, CG16982, dRbx1, ROC1, anon-EST:Posey65, Rbx1/Roc, EG:115C2.11, dRoc1, dRoc1a, Rbx1, CK01110, BEST:CK01110, Roc1alpha" "IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001841=Zinc finger, RING-type, IPR024766=Zinc finger, RING-H2-type" CG16982 16-Dec-15 2015_12 ENSDARG00000038030(rbx1) YOL133W(HRT1) WBGene00004320(rbx-1) ENSG00000100387(RBX1) " larval stage , embryonic stage -- adult stage " " dorsal mesothoracic disc

ubiquitous , organism

" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18483 K -1.085685316 0.01639769 0.534721498 -1.216617104 2.767043778 2.364761323 FBgn0031213 galectin galectin http://flybase.net/reports/FBgn0031213.html protein_coding_gene "0030246=carbohydrate binding, 0015143=urate transmembrane transporter activity, 0016936=galactoside binding" 0008039=synaptic target recognition 0005829=cytosol "Dmgal, CG11372" "IPR001079=Galectin, carbohydrate recognition domain, IPR013320=Concanavalin A-like lectin/glucanase domain" CG11372 16-Dec-15 2015_12 "ENSDARG00000069058(zgc:171951),ENSDARG00000054816,ENSDARG00000041060(zgc:92326),ENSDARG00000025903(lgals9l1)" "ENSXETG00000007928(),ENSXETG00000019079(lgals9),ENSXETG00000002843(lgals4)" "ENSMUSG00000001123(Lgals9),ENSMUSG00000053964(Lgals4),ENSMUSG00000057554(Lgals8)" "ENSG00000171747(LGALS4),ENSG00000170298(LGALS9B),ENSG00000171916(LGALS9C),ENSG00000168961(LGALS9),ENSG00000116977(LGALS8)" " embryonic stage | stage 13-15 , embryonic stage | stage 8-11 , embryonic stage | stage 8-16 , larval stage , embryonic stage | stage 6,7 , embryonic stage&&larval stage&&adult stage , embryonic stage | stage 13-16 , embryonic stage | early " " embryonic visceral muscle

, embryonic hindgut

, mesoderm

, embryonic central nervous system

, macrophage

, mesoderm anlage

, larval hemocyte

, crystal cell

, embryonic somatic muscle

, lamellocyte

, embryonic foregut

, plasmatocyte

" embryonic stage && larval stage && adult stage FBgn0015773 NetA Netrin-A http://flybase.net/reports/FBgn0015773.html "FBtr0073942, FBpp0073759" protein_coding_gene "0007411=axon guidance, 0008347=glial cell migration, 0070983=dendrite guidance, 0008045=motor neuron axon guidance, 2000289=regulation of photoreceptor cell axon guidance" "0005578=proteinaceous extracellular matrix, 0005829=cytosol" "Netrin, netrin A, netrinA, NetrinA, CT27014, NETRIN, net, Netrin A, D-netrin-A, CG18657, netrin, D-netrin, netA" "IPR001134=Netrin domain, IPR008211=Laminin, N-terminal, IPR008993=Tissue inhibitor of metalloproteinases-like, OB-fold, IPR018933=Netrin module, non-TIMP type, IPR002049=Laminin EGF domain" CG18657 16-Dec-15 2015_12 "ENSDARG00000033733(ntn1a),ENSDARG00000022531(ntn1b)" WBGene00006746(unc-6) "ENSXETG00000019519(NTN1),ENSXETG00000020288(NTN3),ENSXETG00000014390(NTN5)" "ENSMUSG00000020902(Ntn1),ENSMUSG00000079662(Ntn3)" "ENSG00000065320(NTN1),ENSG00000162068(NTN3)" " embryonic stage , embryonic stage | stage 12-13 , embryonic stage | stage 12-17 , embryonic stage -- adult stage , embryonic stage | stage 13-17 , embryonic stage | stage 13,14 , embryonic stage | early , embryonic stage | stage 14 " " embryonic neuron

, embryonic nervous system | restricted

, VUM neuron

, midline glial cell

, mesectoderm

, ventral thoracic disc | precursor

, mesoderm anlage

, embryonic brain | restricted

, epidermis | lateral | restricted

, abdominal 2--7 dorsal acute muscle 2

, abdominal 2--7 dorsal acute muscle 1

, visceral mesoderm

, neuroblast MNB

" " embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 12-17 , embryonic stage | stage 13 , embryonic stage | stage 6 " " visceral mesoderm

, larval muscle system

, neuron &&of embryonic nervous system

, midline glial cell

, ventral furrow

, embryonic/larval tracheal system

, mesectoderm

" "neuroanatomy defective,oxidative stress response defective" "embryonic/larval glial cell,optic lobe,photoreceptor cell R8 stalk,transverse nerve,commissure,axon-537.4,optic nerve,photoreceptor cell & axonGMR.PF,photoreceptor cell & axon,lamina,intersegmental nerve,axonelav.PLu, -537.4" FBgn0005777 PpD3 Protein phosphatase D3 http://flybase.net/reports/FBgn0005777.html "FBgn0010250, FBgn0023176, FBgn0037740" protein_coding_gene 0004722=protein serine/threonine phosphatase activity "0000278=mitotic cell cycle, 0006470=protein dephosphorylation" "0005634=nucleus, 0005829=cytosol, 0005737=cytoplasm" "DmPP5, PP5 85E, D3, DmPpp5-85E, CG8402, PP5, protein phosphatase from PCR fragment D3, Pp5-85E" "IPR019734=Tetratricopeptide repeat, IPR011236=Serine/threonine protein phosphatase 5, IPR001440=Tetratricopeptide repeat 1, IPR029052=Metallo-dependent phosphatase-like, IPR013026=Tetratricopeptide repeat-containing domain, IPR013235=PPP domain, IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR011990=Tetratricopeptide-like helical domain, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG8402 16-Dec-15 2015_12 ENSDARG00000034313(zgc:110801) YGR123C(PPT1) WBGene00012665(pph-5) ENSXETG00000018265(pp5c) ENSMUSG00000003099(Ppp5c) ENSG00000011485(PPP5C) embryonic stage -- adult stage " embryonic stage , larval stage--adult stage " viable FBgn0004370 Ptp10D Protein tyrosine phosphatase 10D http://flybase.net/reports/FBgn0004370.html FBgn0019946 protein_coding_gene "0004721=phosphoprotein phosphatase activity, 0004728=receptor signaling protein tyrosine phosphatase activity, 0004725=protein tyrosine phosphatase activity, 0005001=transmembrane receptor protein tyrosine phosphatase activity" "0007417=central nervous system development, 0008045=motor neuron axon guidance, 0006470=protein dephosphorylation, 0007411=axon guidance, 0007424=open tracheal system development, 0007616=long-term memory" "0045177=apical part of cell, 0005886=plasma membrane, 0030424=axon" "PTP10D, dptp, CG1817, CT4920, Ptp10, DPTP10D, DPTP, Protein tyrosine phosphatase 10B, R-PTP 10D, 10D, DPTP[[10D]], ptp10D" "IPR029021=Protein-tyrosine phosphatase-like, IPR013783=Immunoglobulin-like fold, IPR016130=Protein-tyrosine phosphatase, active site, IPR003961=Fibronectin type III, IPR000242=PTP type protein phosphatase, IPR003595=Protein-tyrosine phosphatase, catalytic, IPR000387=Tyrosine specific protein phosphatases domain" CG1817 16-Dec-15 2015_12 WBGene00009717(dep-1) ENSXETG00000011378(PTPRB) ENSMUSG00000020154(Ptprb) ENSG00000127329(PTPRB) " embryonic stage , embryonic stage | 9-18hr " embryonic central nervous system | segmentally repeated pattern

" embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 12-17 , embryonic stage | stage 14-17 , embryonic stage | stage 13-15 " " longitudinal connective

, embryonic/larval salivary gland

, ventral nerve cord | restricted

, embryonic/larval trachea

, ventral nerve cord

, ventral nerve cord commissure

, commissure

" "viable,memory defective,neuroanatomy defective,fertile,partially lethal - majority die,some die during pupal stage,visible" "macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval optic neuropil,trichogen cell" FBgn0000658 fj four-jointed http://flybase.net/reports/FBgn0000658.html protein_coding_gene "0017147=Wnt-protein binding, 0004672=protein kinase activity" "0035159=regulation of tube length, open tracheal system, 0045198=establishment of epithelial cell apical/basal polarity, 0042067=establishment of ommatidial planar polarity, 0007444=imaginal disc development, 0007446=imaginal disc growth, 0016348=imaginal disc-derived leg joint morphogenesis, 0001736=establishment of planar polarity, 0007474=imaginal disc-derived wing vein specification, 0001737=establishment of imaginal disc-derived wing hair orientation, 0060071=Wnt signaling pathway, planar cell polarity pathway, 0044719=regulation of imaginal disc-derived wing size, 0006468=protein phosphorylation, 0007267=cell-cell signaling, 0007449=proximal/distal pattern formation, imaginal disc" "0005886=plasma membrane, 0016021=integral component of membrane" "Four-jointed, Four-Jointed, CG10917, Fj, four jointed" IPR024868=Four-jointed box protein 1/four-jointed protein CG10917 16-Dec-15 2015_12 ENSDARG00000035873 ENSXETG00000024642(FJX1) ENSMUSG00000075012(Fjx1) " pupal stage , larval stage | third instar " " ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, larval outer optic anlage

, lamina

, eye-antennal disc | gradient

, ventral thoracic disc

, tibia

, dorsal mesothoracic disc

, eye-antennal disc | restricted

" "viable,visible,recessive,cell polarity defective,somatic clone,lethal,dominant,planar polarity defective,cell non-autonomous,cell autonomous,size defective" "wing vein,ectopic,wing,leg,tarsal segment,eye,abdomen,tarsal segment 2,tarsal segment 3,joint,ommatidium,somatic clone,photoreceptor cell R3,photoreceptor cell R4,mesothoracic tergum,coxa,arista,scutellum,third segment of antenna,abdominal tergite 2,metatarsus,cell non-autonomous,tergite,adult cuticle,microchaeta,macrochaeta,wing hair,cell autonomous,abdominal segment 2 & microchaeta,abdominal segment 2 & macrochaeta,distal,embryonic/larval dorsal trunk,trichome & tergite | cell non-autonomous | somatic clone,wing blade,tarsal segment 4,tibia,femur,lens,posterior,crossvein,dorsal,ventral,posterior compartment,anterior crossvein,trichome & tergite | cell non-autonomous | somatic cloneë±Tub84B.PL,eye disc,posterior crossvein,wing vein L4,anterior/posterior compartment boundary" FBgn0000392 cup cup http://flybase.net/reports/FBgn0000392.html protein_coding_gene "0003723=RNA binding, 0045182=translation regulator activity, 0005515=protein binding" "0048477=oogenesis, 0009953=dorsal/ventral pattern formation, 0007319=negative regulation of oskar mRNA translation, 0051297=centrosome organization, 0007297=ovarian follicle cell migration, 0007143=female meiotic division, 0008298=intracellular mRNA localization, 0045132=meiotic chromosome segregation, 0006417=regulation of translation, 0051276=chromosome organization, 0017148=negative regulation of translation, 0007317=regulation of pole plasm oskar mRNA localization" "0005875=microtubule associated complex, 0005886=plasma membrane, 0005641=nuclear envelope lumen, 0000932=cytoplasmic mRNA processing body, 0005634=nucleus, 0005737=cytoplasm, 0005829=cytosol" "DmCup, Cup, fs(2)cup, CUP, i239, CG11181, fs(1)cup" IPR018862=Eukaryotic translation initiation factor 4E binding protein CG11181 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage | female && oogenesis stage , oogenesis stage | stage S1-8 , adult stage | male , oogenesis stage && adult stage | female , oogenesis stage | stage S10-14 , embryonic stage | early " " germline stem cell

, germarium

, germarium region 1

, germarium region 3

, cystoblast

, germarium region 2a

, germarium region 2b

, ovary

" " embryonic stage | early , spermatogenesis && adult stage , adult stage && oogenesis stage " " testis

, nurse cell

, oocyte

" "female sterile,recessive,partially,viable" "egg chamber,nurse cell & chromatin,chorion,karyosome,dorsal appendage,egg,maternal effect,cleavage nucleus,ovary,nurse cell,mitosis | ectopic | oogenesis stage S5" FBgn0004514 Oct-TyrR Octopamine-Tyramine receptor http://flybase.net/reports/FBgn0004514.html "FBgn0002983, FBgn0004109, FBgn0011463, FBgn0037148" protein_coding_gene "0004989=octopamine receptor activity, 0008226=tyramine receptor activity, 0008227=G-protein coupled amine receptor activity" "1900738=positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway, 0007608=sensory perception of smell, 0010578=regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, 0007211=octopamine or tyramine signaling pathway" "0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane" "Tyramine receptor, hono, Octopamine receptor 1, tyramine receptor, DmTAR1, Oct/Tyr receptor, Dmoct/tyr, TYR, Tyr, CG7485, TyrR, honoka, TAR1, Ocr, l(3)neo30, OctyR99AB, Octopamine/Tyramine receptor, DrmOTR, OA-R, Tyramine-receptor, OcR, Tyr-dro, OAR_DROME, OctoR1, TyR, Octopamine receptor, octopamine/tyramine receptor, DmTyrR, OTR" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR002002=Octopamine receptor, IPR017452=GPCR, rhodopsin-like, 7TM" CG7485 16-Dec-15 2015_12 WBGene00004777(ser-2) ENSXETG00000014812(HTR1A) adult stage adult head

"neurophysiology defective,smell perception defective,viable,lethal,recessive,fertile" neuromuscular junction DRSC11883 I 1.887743085 0.554246745 0.596165394 -0.245486263 0.401012646 -0.070669498 FBgn0010215 ë±-Cat ë± Catenin http://flybase.net/reports/FBgn0010215.html FBan0017947 protein_coding_gene "0051015=actin filament binding, 0008092=cytoskeletal protein binding, 0005515=protein binding, 0045296=cadherin binding, 0005198=structural molecule activity, 0003779=actin binding" "0007016=cytoskeletal anchoring at plasma membrane, 0060323=head morphogenesis, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0007155=cell adhesion, 0007163=establishment or maintenance of cell polarity, 0034332=adherens junction organization" "0005912=adherens junction, 0005886=plasma membrane, 0030055=cell-substrate junction, 0016342=catenin complex, 0005914=spot adherens junction, 0005913=cell-cell adherens junction, 0015629=actin cytoskeleton, 0005915=zonula adherens" "alphaCat, alpha-catenin, alphaCAT, Dalpha-catenin, a-cat, alphaCatenin, Dalpha-Cat, LD30423p, alpha-Cat, alpha-Catenin, DalphaCatenin, Dalpha-cadherin, alphacatenin, Dalphacatenin, a-catenin, alphacat, Dalpha-cat, Dalphacat, Dmcatp, alpha-cat, alpha Catenin, Dalpha-Catenin, CT39986, alpha-ctn, CG17947, DalphaC, alpha catenin, a-Cat, D-alpha-catenin, alpha-CAT" "IPR000633=Vinculin, conserved site, IPR001033=Alpha-catenin, IPR006077=Vinculin/alpha-catenin" CG17947 16-Dec-15 2015_12 ENSDARG00000024785(ctnna2) WBGene00001978(hmp-1) ENSXETG00000008405(CTNNA1) "ENSMUSG00000063063(Ctnna2),ENSMUSG00000037815(Ctnna1)" "ENSG00000066032(CTNNA2),ENSG00000044115(CTNNA1)" " larval stage | third instar , embryonic stage && pupal stage && adult stage " organism

" embryonic stage | stage 16 , embryonic stage | stage 11 , larval stage | third instar , embryonic stage | stage >=5 " " embryonic/larval midgut

, ventral midline

, eye disc

, epidermis

, ommatidial precursor cluster

, ventral thoracic disc | restricted

, embryonic/larval foregut

, embryonic peripheral nervous system

, organism

, embryonic/larval salivary gland duct

, morphogenetic furrow |anterior to

ubiquitous , morphogenetic furrow | posterior to | restricted

, embryonic/larval hindgut

, ectoderm

, embryonic central nervous system

" "visible,increased cell number,lethal - all die before end of embryonic stage,cell lethal,somatic clone,cell migration defective,neuroanatomy defective,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage" "eye | adult stage,inter-ommatidial precursor cell,supernumerary,tertiary pigment cell,embryonic/larval cuticle,cephalopharyngeal skeleton,imaginal disc,somatic clone,ovary,egg chamber,border follicle cell,embryonic head,follicle cell,cone cell,male genitalia,adherens junction | somatic clone,epithelium,female germline cyst" DRSC11917 E 1.409755896 0.530139397 1.997866869 0.017857608 -0.46731122 0.047406125 FBgn0261800 LanB1 LanB1 http://flybase.net/reports/FBgn0261800.html "FBgn0002527, FBgn0259294" protein_coding_gene "0048513=organ development, 0009887=organ morphogenesis, 0030198=extracellular matrix organization, 0009888=tissue development, 0070831=basement membrane assembly, 0055013=cardiac muscle cell development, 0034446=substrate adhesion-dependent cell spreading, 0033627=cell adhesion mediated by integrin, 0045089=positive regulation of innate immune response, 0048598=embryonic morphogenesis, 0016477=cell migration, 0003143=embryonic heart tube morphogenesis, 0008406=gonad development, 0050829=defense response to Gram-negative bacterium" "0012505=endomembrane system, 0031012=extracellular matrix, 0005604=basement membrane, 0005605=basal lamina" "misplaced gonads, Lam-B1, lamininB, LM-B1/beta, BcDNA:LD21794, LanB, Laminin B1, LamB1, laminin beta1, laminin beta, CT22015, mspl, EP-600, Laminin, laminin beta-chain, beta1, Lan B1, CG7123, laminin B1, laminin, laminin B1 subunit, lamB1, LamininB1, Lambeta" "IPR013032=EGF-like, conserved site, IPR013015=Laminin IV type B, IPR002049=Laminin EGF domain, IPR008211=Laminin, N-terminal" CG7123 16-Dec-15 2015_12 "ENSDARG00000002084(hm:zehs0001),ENSDARG00000045524(si:dkey-183c16.5)" WBGene00002247(lam-1) "ENSXETG00000008622(LAMB2),ENSXETG00000012279(LAMB1)" "ENSMUSG00000002900(Lamb1-1),ENSMUSG00000052911(Lamb2)" "ENSG00000091136(LAMB1),ENSG00000172037(LAMB2)" " embryonic stage | late , embryonic stage | stage >12 , embryonic stage | stage 11-12 , embryonic stage " " embryonic/larval midgut

, hemocyte

, head mesoderm

, ventral midline

, embryonic brain

, embryonic/larval fat body

, ventral nerve cord

, visceral mesoderm

, sense organ

, glial cell | lateral

, somatic mesoderm

, ectoderm

, interface glial cell

" " embryonic stage | stage 13-15 , embryonic stage , embryonic stage | 10-13 hr " " segmental nerve

, fat body

, ventral nerve cord

, neuropil associated CNS glial cell

, spiracle

, embryonic/larval midgut

, glial cell

, hemocyte

, embryonic/larval digestive system

, intersegmental nerve

, myoblast &&of larval muscle system

, embryonic somatic muscle

, embryonic brain

, epidermis

" FBgn0011273 Acam Androcam http://flybase.net/reports/FBgn0011273.html FBgn0039375 protein_coding_gene "0070855=myosin VI head/neck binding, 0005509=calcium ion binding" "0030048=actin filament-based movement, 0005513=detection of calcium ion" "0005634=nucleus, 0070865=investment cone, 0005737=cytoplasm, 0031476=myosin VI complex" "androcalmodulin, Acam, Camr97A, ACaM, CG17769, And, androcam, Calmodulin-related 97A" "IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair" CG17769 16-Dec-15 2015_12 YBR109C(CMD1) viable DRSC24252 K 0.161085217 0.219800005 -0.043283888 -0.097075093 -1.756087972 -0.558742902 FBgn0008635 ë_COP Coat Protein (coatomer) ë_ http://flybase.net/reports/FBgn0008635.html protein_coding_gene 0005198=structural molecule activity "0006886=intracellular protein transport, 0045089=positive regulation of innate immune response, 0000902=cell morphogenesis, 0006890=retrograde vesicle-mediated transport, Golgi to ER, 0050829=defense response to Gram-negative bacterium, 0006909=phagocytosis, 0010883=regulation of lipid storage" "0030126=COPI vesicle coat, 0005794=Golgi apparatus" "betaCOP, COPI beta subunit, Beta Cop, beta-Cop, Beta coatomer protein, CG6223, BetaCop, beta-CopII, betaCop, beta-coatomer protein, beta coatomer protein, bcop, beta-COP, COPI, BcDNA.GH09317, BcDNA:GH09317" "IPR011989=Armadillo-like helical, IPR029446=Coatomer beta subunit, appendage platform domain, IPR011710=Coatomer beta subunit, C-terminal, IPR002553=Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR016460=Coatomer beta subunit (COPB1), IPR016024=Armadillo-type fold" CG6223 16-Dec-15 2015_12 ENSDARG00000056557(copb1) YDR238C(SEC26) WBGene00021292(Y25C1A.5) ENSXETG00000019682(COPB1) ENSMUSG00000030754(Copb1) ENSG00000129083(COPB1) embryonic stage | early "lethal,visible" wing DRSC20312 IEK 0.151197316 2.081650889 2.845743315 -3.858600187 0.26842895 -1.741480973 FBgn0053526 PNUTS PNUTS http://flybase.net/reports/FBgn0053526.html "FBgn0031291, FBgn0051657" protein_coding_gene "0008157=protein phosphatase 1 binding, 0003677=DNA binding, 0019888=protein phosphatase regulator activity, 0046872=metal ion binding" "0035304=regulation of protein dephosphorylation, 0006351=transcription, DNA-templated, 0006909=phagocytosis, 0010467=gene expression, 0048589=developmental growth, 0050790=regulation of catalytic activity, 0006605=protein targeting" 0005634=nucleus "PNUTS-RB, Pnuts, CG31657, CG4124, PNUTSDm, CG33526" "IPR017923=Transcription factor IIS, N-terminal, IPR000571=Zinc finger, CCCH-type" CG33526 16-Dec-15 2015_12 ENSDARG00000032651(ppp1r10) ENSXETG00000027931(PPP1R10) ENSMUSG00000039220(Ppp1r10) "ENSG00000204569(PPP1R10),ENSG00000206407,ENSG00000206489" "lethal,lethal - all die before end of larval stage,cell growth defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" "eye,ommatidium" DRSC00638 IE -1.500523695 0.476626738 -0.074073381 -4.21777324 -0.485428196 0.755679097 FBgn0051840 CR31840 http://flybase.net/reports/FBgn0051840.html non_protein_coding_gene CG31840 CR31840 16-Dec-15 2015_12 "viable,body color defective" mesothoracic tergum DRSC25153 IEK -1.72516516 -0.07896494 -3.486352298 -0.995149178 0.586345853 1.526022371 FBgn0035824 CG8281 http://flybase.net/reports/FBgn0035824.html protein_coding_gene IPR006578=MADF domain CG8281 16-Dec-15 2015_12 viable DRSC10976 E -0.322101669 0.427372901 -1.749474865 0.072530195 0.401121132 -1.073239173 FBgn0266369 Mtp Microsomal triacylglycerol transfer protein http://flybase.net/reports/FBgn0266369.html "FBgn0032904, FBgn0260096, FBgn0260097" protein_coding_gene "0008525=phosphatidylcholine transporter activity, 0017129=triglyceride binding" "0035149=lumen formation, open tracheal system, 0006641=triglyceride metabolic process, 0048813=dendrite morphogenesis, 0006869=lipid transport, 0042157=lipoprotein metabolic process, 0008039=synaptic target recognition" "0005811=lipid particle, 0012505=endomembrane system" "MTP, CT3751, CG9342, dMTP, 2L3637, microsomal triglyceride transfer protein, Microsomal triglyceride transfer protein, 2L4501, microsomal triacylglycerol transfer protein, mtp" "IPR001747=Lipid transport protein, N-terminal, IPR015819=Lipid transport protein, beta-sheet shell, IPR011030=Vitellinogen, superhelical, IPR015816=Vitellinogen, beta-sheet N-terminal" CG9342 16-Dec-15 2015_12 ENSDARG00000008637(LOC100332220) WBGene00001099(dsc-4) "ENSXETG00000009307(MTTP),ENSXETG00000027557()" ENSMUSG00000028158(Mttp) ENSG00000138823(MTTP) DRSC03216 K 0.216683501 -0.142061644 1.07902005 -0.038449183 1.97351512 0.973386424 FBgn0260932 cuff cutoff http://flybase.net/reports/FBgn0260932.html "FBgn0000390, FBgn0033662" protein_coding_gene "0030723=ovarian fusome organization, 0030727=germarium-derived female germ-line cyst formation, 0048477=oogenesis, 0030717=karyosome formation, 0030719=P granule organization, 0009953=dorsal/ventral pattern formation" "0005634=nucleus, 0048471=perinuclear region of cytoplasm" CG13190 IPR013961=RAI1-like CG13190 16-Dec-15 2015_12 DRSC06315 I 1.574092521 0.038776469 0.312761507 0.648358453 -0.827919352 -0.909439978 FBgn0040035 CG40368 http://flybase.net/reports/FBgn0040035.html "FBgn0058368, FBan0040368" protein_coding_gene CG12458 16-Dec-15 2015_12 DRSC20814 I 2.204439971 -1.284546364 0.4780912 -0.71284196 FBgn0037989 ATP8B ATPase 8B http://flybase.net/reports/FBgn0037989.html protein_coding_gene "0015662=ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, 0000287=magnesium ion binding, 0005524=ATP binding, 0004012=phospholipid-translocating ATPase activity" "0045332=phospholipid translocation, 0050911=detection of chemical stimulus involved in sensory perception of smell, 0032880=regulation of protein localization" "0071683=sensory dendrite, 0005929=cilium, 0016021=integral component of membrane" "DmCG14741, CG14741, dATP8B" "IPR023214=HAD-like domain, IPR018303=P-type ATPase, phosphorylation site, IPR008250=P-type ATPase, A domain, IPR023299=P-type ATPase, cytoplasmic domain N, IPR006539=P-type ATPase, subfamily IV, IPR001757=P-type ATPase" CG14741 16-Dec-15 2015_12 ENSDARG00000062040(LOC100330945) WBGene00019166(tat-2) ENSXETG00000008789(ATP8B4) "ENSMUSG00000060671(Atp8b2),ENSMUSG00000060131,ENSMUSG00000028457(Atp8b5)" "ENSG00000143515(ATP8B2),ENSG00000104043(ATP8B4)" "viable,neurophysiology defective,smell perception defective,fertile" antennal olfactory receptor neuron DRSC14961 K 0.014231814 -0.105551607 0.585168408 0.252171967 0.408243588 1.804688201 FBgn0001226 Hsp27 Heat shock protein 27 http://flybase.net/reports/FBgn0001226.html "FBgn0010232, FBgn0044559" protein_coding_gene 0005515=protein binding "0050832=defense response to fungus, 0042742=defense response to bacterium, 0007476=imaginal disc-derived wing morphogenesis, 0042595=behavioral response to starvation, 0042026=protein refolding, 0008340=determination of adult lifespan, 0009408=response to heat" "0005737=cytoplasm, 0005634=nucleus, 0005875=microtubule associated complex" "hsp-27, HSP28, hsp27/26, heatshock protein 27, Heat shock protein 237, anon-WO0140519.69, hsp26, 28, small hsp locus 67B, Dhsp27, heat shock protein hsp27, Protein 27, DmHSP27, HSP27, DmHsp27, hsp 27, heat shock protein 27, hsp27, Hsp 27, CG4466, Hsp28, hsp28, 27, 27K" "IPR008978=HSP20-like chaperone, IPR001436=Alpha crystallin/Heat shock protein, IPR002068=Alpha crystallin/Hsp20 domain, IPR031107=Small heat shock protein HSP20" CG4466 16-Dec-15 2015_12 "ENSDARG00000041065(hspb1),ENSDARG00000058362(LOC100331249),ENSDARG00000052447(cryabb),ENSDARG00000058365(hspb8)" "WBGene00004798(sip-1),WBGene00002020(hsp-16.49),WBGene00002015(hsp-16.1),WBGene00002018(hsp-16.41),WBGene00002016(hsp-16.2),WBGene00008592(F08H9.4)" ENSXETG00000008972(HSPB1) " prepupal stage , embryonic stage | <=2-3 hr , larval stage | late third instar larval stage " organism

" larval stage | first instar , embryonic stage , pupal stage " "viable,fertile,starvation stress response defective,short lived,immune response defective,long lived,male,chemical resistant,female fertile,reduced,visible" trichogen cell DRSC26877 K -0.0594911 0.495705638 0.817929218 0.127726523 -0.086521502 -1.563939182 FBgn0001137 grk gurken http://flybase.net/reports/FBgn0001137.html protein_coding_gene "0008317=gurken receptor binding, 0005154=epidermal growth factor receptor binding" "0030381=chorion-containing eggshell pattern formation, 0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0008314=gurken signaling pathway, 0009952=anterior/posterior pattern specification, 0046843=dorsal appendage formation, 0030714=anterior/posterior axis specification, follicular epithelium, 0016325=oocyte microtubule cytoskeleton organization, 0008070=maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded, 0001708=cell fate specification, 0030722=establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification, 0007173=epidermal growth factor receptor signaling pathway, 0007298=border follicle cell migration, 0000578=embryonic axis specification, 0007314=oocyte anterior/posterior axis specification, 0001709=cell fate determination, 0007309=oocyte axis specification, 0007310=oocyte dorsal/ventral axis specification" "0005576=extracellular region, 0005783=endoplasmic reticulum" "CT32746, Gurken, CG17610, GURKEN, Grk, GRK, s-Grk" "IPR000742=EGF-like domain, IPR013032=EGF-like, conserved site" CG17610 16-Dec-15 2015_12 ", adult stage && oogenesis stage | stage S1-7 , adult stage | female , oogenesis stage | stage >S8 , adult stage && oogenesis stage | stage >S8 " " stage S9 oocyte && stage S10 oocyte

anterior & dorsal , nurse cell

, stage S8 oocyte | anterior

, stage S8 oocyte

anterior , stage S6 oocyte

posterior , oocyte | anterior

{ 0 Egfr* } , oocyte | dorsal <&> anterior

, oocyte | dorsal <&> anterior

{ + fs(1)K10* } , oocyte | anterior

{ + capu* } , oocyte | dorsal <&> anterior

{ 0 cni* } , stage S9 oocyte | anterior & dorsal

, oocyte | anterior

{ + spir* } , oocyte | anterior

{ + sqd* } " " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S8 , adult stage && oogenesis stage | stage , oocyte | restricted

, oocyte

, stage S10 oocyte

anterior & dorsal , germarium region 2b

" "female sterile,lethal,maternal effect,recessive,viable,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,visible" "ventral furrow,supernumerary,ectopic,embryonic/first instar larval cuticle,follicle cell,embryo,ventral,dorsal appendage,egg operculum,maternal effect,egg,egg chamber,chorion,oocyte,female germline cyst,oocyte nucleus,vitelline membrane,cold sensitive,micropyle,germline clone,microtubule & oocyte,border follicle cell,ovary,oocyte & microtubule,pericentriolar material & oocyte | posterior,wing vein,wing,wing vein L4" FBgn0005696 DNApol-ë±73 DNA polymerase ë± 73kD http://flybase.net/reports/FBgn0005696.html protein_coding_gene "0003887=DNA-directed DNA polymerase activity, 0003677=DNA binding" "0006261=DNA-dependent DNA replication, 0006270=DNA replication initiation" "0005658=alpha DNA polymerase:primase complex, 0005635=nuclear envelope, 0005634=nucleus" "DNA polymerase alpha, Polalpha 73kDa, polalpha, Pol, DNA polymerase alpha primase 73 kda subunit, DNApolalpha, DNA polymerase alpha 73 kD, DNApol-alpha73, CG5923, DNApol-alpha72, DNA pol-73, Polalpha, DNA polalpha, DNApol-alpha, pol alpha, Dmpol alpha, DNA-polymerase alpha, POLA, B subunit, DNA polymerase 73K" "IPR016722=DNA polymerase alpha, subunit B, IPR007185=DNA polymerase alpha/epsilon, subunit B" CG5923 16-Dec-15 2015_12 ENSDARG00000015070(pola2) WBGene00001002(div-1) ENSXETG00000023289(pola2) ENSMUSG00000024833(Pola2) ENSG00000014138(POLA2) egg stage | fertilized egg " female pronucleus

, male pronucleus

" visible eye FBgn0020381 Dredd Death related ced-3/Nedd2-like caspase http://flybase.net/reports/FBgn0020381.html "FBgn0013388, FBgn0023366, FBgn0024454, FBtr0070152, FBpp0070147, FBtr0070153, FBpp0070148, FBtr0070154, FBpp0070149" protein_coding_gene "0004175=endopeptidase activity, 0004197=cysteine-type endopeptidase activity, 0005515=protein binding, 0016505=peptidase activator activity involved in apoptotic process" "0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0007291=sperm individualization, 0043069=negative regulation of programmed cell death, 0016485=protein processing, 0006915=apoptotic process, 0061057=peptidoglycan recognition protein signaling pathway, 0048935=peripheral nervous system neuron development, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0045089=positive regulation of innate immune response, 0050829=defense response to Gram-negative bacterium, 0002230=positive regulation of defense response to virus by host, 0006952=defense response, 0045087=innate immune response, 0006955=immune response" 0005737=cytoplasm "dredd, Dcp-2, Dcp2, Dcp-2/Dredd, EG:115C2.9, CASP8_DROME, caspase, Dredd/DCP-2, Ced-3-like/Nedd2-like protein, unnamed, DREDD, death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein, Drosophila caspase, CG7486, Death related ced-3/Nedd2-like protein, dcp-2/dredd, anon-1BCa, DCP-2/DREDD, DCP-2, Death caspase-2, Redd, Dedd, dDredd, DCP2" "IPR029030=Caspase-like domain, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR011600=Peptidase C14, caspase domain, IPR015917=Peptidase C14A, caspase precursor p45, core, IPR002138=Peptidase C14, caspase non-catalytic subunit p10" CG7486 16-Dec-15 2015_12 WBGene00000820(csp-2) "ENSG00000064012(CASP8),ENSG00000003400(CASP10),ENSG00000003402(CFLAR)" " embryonic stage | stage 11 , adult stage && oogenesis stage | stage S10 , adult stage , adult stage && oogenesis stage | stage S10-13 , embryonic stage , embryonic stage | stage <=10 , embryonic stage | stage 13 , embryonic stage | stage 16 " " embryonic gnathal segment | restricted

, oocyte

, embryonic labral segment | restricted

, nurse cell

,

ubiquitous , dorsal ridge

, embryonic central nervous system

, ventral nerve cord

" "viable,fertile,visible,dominant,immune response defective,wild-type,oxidative stress response defective,recessive,increased cell death,conditional,radiation resistant,decreased cell death,neuroanatomy defective" "mesothoracic tergum,macrochaeta,ectopic,spermatid,intestinal stem cell,peptidergic neuron" DRSC18461 E 0.060605026 -0.476640838 -1.50298327 0.303757827 0.553468834 0.759500968 FBgn0028675 Sur Sulfonylurea receptor http://flybase.net/reports/FBgn0028675.html FBgn0025710 protein_coding_gene "0008281=sulfonylurea receptor activity, 0042626=ATPase activity, coupled to transmembrane movement of substances, 0005524=ATP binding" "0006031=chitin biosynthetic process, 0001666=response to hypoxia, 0007507=heart development, 0055085=transmembrane transport" "0016021=integral component of membrane, 0008282=ATP-sensitive potassium channel complex" "CG5772, dSur, CK00325, CYO, dsur, Dme_CG5772, dSUR, sulfonylurea receptor, sur, sulfonyl urea receptor, Dsur, BEST:CK00325, SUR, Sulphonylurea receptor, cyo" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain, IPR003439=ABC transporter-like" CG5772 16-Dec-15 2015_12 ENSDARG00000015985(abcc9) "ENSMUSG00000030249(Abcc9),ENSMUSG00000040136(Abcc8)" "ENSG00000069431(ABCC9),ENSG00000006071(ABCC8)" " embryonic stage | stage >=10 , embryonic stage | stage >=15 , adult stage , embryonic stage | early , larval stage " " embryonic/larval dorsal vessel

, embryonic/larval salivary gland

, embryonic/larval posterior spiracle

, embryonic/larval tracheal system

" "stress response defective,viable,immune response defective" adult heart FBgn0008651 lbl ladybird late http://flybase.net/reports/FBgn0008651.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007501=mesodermal cell fate specification, 0016477=cell migration, 0042659=regulation of cell fate specification, 0007480=imaginal disc-derived leg morphogenesis, 0008544=epidermis development, 0006355=regulation of transcription, DNA-templated, 0007519=skeletal muscle tissue development, 0007417=central nervous system development, 0007507=heart development, 0051450=myoblast proliferation, 0007520=myoblast fusion, 0045664=regulation of neuron differentiation, 0007483=genital disc morphogenesis, 0007517=muscle organ development" 0005634=nucleus "Lbl, NK?, NK-cluster homeobox 4, nkch4, ladybird, Lb, lb, lady-bird-late, Ladybird, NKch4, CG6570" "IPR001356=Homeobox domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR000047=Helix-turn-helix motif" CG6570 16-Dec-15 2015_12 WBGene00003377(mls-2) "ENSXETG00000027771(HMX2),ENSXETG00000015419()" ENSMUSG00000034968(Lbx2) " embryonic stage | stage 10-13 , embryonic stage | late , larval stage | third instar , embryonic stage | stage 13 , embryonic stage | stage >10 , embryonic stage | stage 15 , embryonic stage | stage 13-17 , pupal stage , embryonic stage | 8-20 hr " " dorsal ectoderm &&of abdominal segment 1--7

, central nervous system | restricted

, epidermis | segmentally repeated

, anal pad

, epidermis | dorsal

, ventral nerve cord

, ectoderm | ventral

, segment border muscle

, embryonic peripheral nervous system | restricted

, embryonic central nervous system | restricted

" " embryonic stage | stage 10-13 , embryonic stage | late , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage >10 " " dorsal ectoderm &&of abdominal segment 1--7

, central nervous system | restricted

, epidermis | dorsal

, embryonic peripheral nervous system | restricted

, ectoderm | ventral

, segment border muscle

, anal pad

" "viable,fertile" "embryonic/larval dorsal vessel,precursor,dorsal denticle,EL neuron,central nervous system,exit glial cell,ectopic,glial cell,intersegmental nerve,prothoracic segmental nerve" FBgn0031877 CG10399 http://flybase.net/reports/FBgn0031877.html protein_coding_gene 0004419=hydroxymethylglutaryl-CoA lyase activity 0006551=leucine metabolic process "0005777=peroxisome, 0005875=microtubule associated complex, 0005759=mitochondrial matrix" 145934_at "IPR013785=Aldolase-type TIM barrel, IPR000891=Pyruvate carboxyltransferase" CG10399 16-Dec-15 2015_12 "ENSDARG00000021220(hmgcl),ENSDARG00000057377" "YDL182W(LYS20),YDL131W(LYS21)" WBGene00022150(Y71G12B.10) ENSXETG00000015336(HMGCL) "ENSMUSG00000028672(Hmgcl),ENSMUSG00000007908(Hmgcll1)" "ENSG00000117305(HMGCL),ENSG00000146151(HMGCLL1)" "partially lethal - majority die,some die during pupal stage" DRSC02051 K 1.05765146 0.186094507 -0.04194903 0.312547875 2.137781602 0.523380965 FBgn0259221 CG42321 http://flybase.net/reports/FBgn0259221.html "FBgn0033837, FBgn0045898, FBgn0050061" protein_coding_gene "0004012=phospholipid-translocating ATPase activity, 0005524=ATP binding, 0000287=magnesium ion binding, 0015662=ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism" 0045332=phospholipid translocation 0016021=integral component of membrane "CG17034, CG30061, anon-WO0153538.54, DmCG42321" "IPR006539=P-type ATPase, subfamily IV, IPR001757=P-type ATPase, IPR023214=HAD-like domain, IPR018303=P-type ATPase, phosphorylation site, IPR008250=P-type ATPase, A domain, IPR023299=P-type ATPase, cytoplasmic domain N" CG42321 16-Dec-15 2015_12 YAL026C(DRS2) WBGene00013034(tat-1) ENSXETG00000010674(ATP8A2) "ENSMUSG00000037685(Atp8a1),ENSMUSG00000021983(Atp8a2)" "ENSG00000124406(ATP8A1),ENSG00000132932(ATP8A2)" DRSC05421 I 1.524030485 -0.327715361 0.426227973 0.527593874 0.256137851 0.418987414 FBgn0050273 CG30273 http://flybase.net/reports/FBgn0050273.html FBgn0034762 protein_coding_gene CG13515 IPR006629=LPS-induced tumour necrosis factor alpha factor CG30273 16-Dec-15 2015_12 WBGene00013604(Y87G2A.18) viable DRSC22059 I -0.786782566 1.846904577 -0.150942939 0.415192302 1.393556446 0.764823363 FBgn0039452 CG14245 http://flybase.net/reports/FBgn0039452.html "FBgn0052950, FBtr0085041, FBpp0084413, FBtr0085042, FBpp0084414" protein_coding_gene 0008061=chitin binding 0006030=chitin metabolic process 0005576=extracellular region CG32950 IPR002557=Chitin binding domain CG14245 16-Dec-15 2015_12 DRSC14741 I -1.613390109 0.669816434 -0.42018715 0.441402157 -0.592142559 0.39287273 FBgn0052660 CR32660 http://flybase.net/reports/FBgn0052660.html non_protein_coding_gene CR32660 16-Dec-15 2015_12 "viable,fertile" DRSC18942 I -0.643244641 1.511600444 0.192506079 -0.046128039 0.224810805 -0.265033448 FBgn0011754 PhKë_ Phosphorylase kinase ë_ http://flybase.net/reports/FBgn0011754.html FBgn0044448 protein_coding_gene "0005516=calmodulin binding, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding, 0004689=phosphorylase kinase activity" "0006007=glucose catabolic process, 0048598=embryonic morphogenesis, 0006468=protein phosphorylation, 0005978=glycogen biosynthetic process" 0005964=phosphorylase kinase complex "PhKgamma, Phkgamma, EP779, anon-sts6, ESTS:194B3T, CG1830, DPhK-gamma, phosphorylase kinase gamma, Phosphorylase kinase gamma, unnamed" "IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site, IPR020636=Calcium/calmodulin-dependent/calcium-dependent protein kinase, IPR002291=Phosphorylase kinase, gamma catalytic subunit, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site" CG1830 16-Dec-15 2015_12 "ENSDARG00000054208(phkg2),ENSDARG00000030604(phkg1a),ENSDARG00000069498(phkg1b)" WBGene00021753(Y50D7A.3) "ENSXETG00000010064(phkg1),ENSXETG00000021132(PHKG2)" "ENSMUSG00000030815(Phkg2),ENSMUSG00000025537(Phkg1)" "ENSG00000156873(PHKG2),ENSG00000164776(PHKG1)" "viable,fertile,paralytic,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "femur,joint,tibia,cuticle,leg" DRSC20268 K -0.166140575 0.426037955 -0.187649355 -0.154747289 -0.074065569 -1.592921127 FBgn0260639 ë_Tub23C ë_-Tubulin at 23C http://flybase.net/reports/FBgn0260639.html "FBgn0004176, FBgn0040117" protein_coding_gene "0003924=GTPase activity, 0051011=microtubule minus-end binding, 0005525=GTP binding, 0019001=guanyl nucleotide binding, 0005200=structural constituent of cytoskeleton" "0051306=mitotic sister chromatid separation, 0090307=mitotic spindle assembly, 0051726=regulation of cell cycle, 0007020=microtubule nucleation, 0007052=mitotic spindle organization, 0051298=centrosome duplication, 0007017=microtubule-based process, 0007067=mitotic nuclear division, 0051297=centrosome organization, 0010457=centriole-centriole cohesion, 0031122=cytoplasmic microtubule organization" "0045298=tubulin complex, 0008275=gamma-tubulin small complex, 0008274=gamma-tubulin ring complex, 0005815=microtubule organizing center, 0005874=microtubule, 0000242=pericentriolar material, 0000930=gamma-tubulin complex, 0000931=gamma-tubulin large complex, 0005819=spindle, 0005737=cytoplasm" "gammaTUB23C, CG3157, gamma-Tubulin at 23C, gammaTubulin, gammaTub23C, &ggr-tubulin, gamma-tub, gamma tubulin 23C, gamma-Tub, lethal (2) 23Ce, gamma-tubulin23C, 23C-gamma-tubulin, gammaTub, gamma-tubulin 23C, gamma-Tub23C, gamma tubulin, GTUB, D.m.GAMMA-23C, gamma-tub23C, Gamma-tubulin, g-Tubulin, tubulin, 23C gamma-tubulin, gamma-tubulin (23C), gammatub, gamma-Tubulin, gammatub23C, gammatubulin, CG 3157, gamma-tub23, gamma-tubulin, Tub23, gamma-tub 23C, gamma[zy], GTU88*, gammaTub23CD, gamma-tubulin(23C), gamma-tubulin-1, GAMMA23C, gammaTUB, gama-tubulin, l(2)23Ce" "IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal, IPR002454=Gamma tubulin, IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR000217=Tubulin" CG3157 16-Dec-15 2015_12 ENSDARG00000015610(tubgl) YLR212C(TUB4) WBGene00006540(tbg-1) ENSXETG00000014898() "ENSMUSG00000035198(Tubg1),ENSMUSG00000045007(Tubg2)" "ENSG00000131462(TUBG1),ENSG00000037042(TUBG2)" DRSC00820 I 1.847910477 -0.102000106 -0.65449196 -0.05343407 -0.863022883 0.030575329 FBgn0261648 salm spalt major http://flybase.net/reports/FBgn0261648.html "FBgn0004579, FBgn0010546, FBgn0259600" protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0035310=notum cell fate specification, 0007438=oenocyte development, 0007424=open tracheal system development, 0035155=negative regulation of terminal cell fate specification, open tracheal system, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007423=sensory organ development, 0035277=spiracle morphogenesis, open tracheal system, 0006355=regulation of transcription, DNA-templated, 0045465=R8 cell differentiation, 0048098=antennal joint development, 0048644=muscle organ morphogenesis, 0007605=sensory perception of sound, 0045892=negative regulation of transcription, DNA-templated, 0007525=somatic muscle development, 0042659=regulation of cell fate specification, 0007427=epithelial cell migration, open tracheal system, 0030539=male genitalia development, 0045466=R7 cell differentiation, 0008586=imaginal disc-derived wing vein morphogenesis, 0046845=branched duct epithelial cell fate determination, open tracheal system, 0008584=male gonad development, 0001751=compound eye photoreceptor cell differentiation, 0021782=glial cell development, 0007379=segment specification" 0005634=nucleus "spalt M, Spalt major, Spalt, Spalt-major, slam, salII, l(2)03602, sal major, 3602, spalt-major, Salm, B1164, spalt majr, sal, SalM, SAL, salM, Sal, CG6464, spalt, Spalt-M, SPALT, Spalt Major, SALM" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG6464 16-Dec-15 2015_12 "ENSDARG00000058708,ENSDARG00000057586(si:dkey-195c14.1),ENSDARG00000029876,ENSDARG00000044485(sall4)" "ENSXETG00000018417(SALL1),ENSXETG00000000845(SALL3),ENSXETG00000012326(sall4),ENSXETG00000017176(TNeu011p20.1)" ENSMUSG00000024565(Sall3) "ENSG00000103449(SALL1),ENSG00000151514(SALL3),ENSG00000101115(SALL4)" " embryonic stage | stage 5 , embryonic stage | stage 13 , embryonic stage | 1-12 hr , larval stage | third instar , embryonic stage | gastrula , embryonic stage | stage >15 , embryonic stage | embryonic cycle 14 , embryonic stage | stage >=13 " " organism | 10-20% egg length

, embryonic/larval hindgut

, dorsal mesothoracic disc | restricted

, cephalic furrow | posterior

, eye-antennal disc | primordium

, organism | 80% egg length

, genital disc | primordium

, organism | 80-90% egg length

, organism | 60-70% egg length

, organism | 0-20% egg length

, organism | ventro-lateral

, cuticle | primordium & segmentally repeated " " larval stage | third instar , embryonic stage | stage 15-17 , embryonic stage | stage 11 , embryonic stage | stage 16 , embryonic stage | stage 5 , embryonic stage | stage 4 | late , embryonic stage | stage 12 " " dorsal mesothoracic disc | restricted

, embryonic central nervous system

, parasegment 1--3

, embryonic/larval posterior spiracle

, parasegment 14,15

, organism | 60-70% egg length

, ventral neurogenic region

, dorsal mesothoracic disc | dorsal comparment & medial

,

~60-70% egg length , posterior spiracle primordium

, organism | 10-20% egg length

, embryonic/larval tracheal system

, organism | 80-90% egg length

" FBgn0086906 sls sallimus http://flybase.net/reports/FBgn0086906.html "FBgn0003432, FBgn0002186, FBgn0010396, FBgn0010850, FBgn0011512, FBgn0015898, FBgn0020409, FBgn0024279, FBgn0035301, FBgn0035302, FBgn0042183, FBgn0028238" protein_coding_gene "0005515=protein binding, 0003779=actin binding, 0004687=myosin light chain kinase activity, 0008307=structural constituent of muscle" "0007498=mesoderm development, 0040011=locomotion, 0007076=mitotic chromosome condensation, 0007062=sister chromatid cohesion, 0007519=skeletal muscle tissue development, 0016203=muscle attachment, 0007520=myoblast fusion, 0035206=regulation of hemocyte proliferation, 0045214=sarcomere organization, 0007517=muscle organ development" "0005863=striated muscle myosin thick filament, 0005875=microtubule associated complex, 0030018=Z disc, 0030017=sarcomere, 0031674=I band, 0000794=condensed nuclear chromosome" "l(3)rL182, MCP, Kettin, SLS, lethal (3) S002001, l(3)dre8, CG18245, kettin, Sls, KZ, lethal(3)62Ca, Sallimus, CG18242, CG18857, d-titin, titin, unnamed, CT41299, D-titin-KZ, Mitotic Chromosomal Protein, CG1915, TITIN, salimus, anon-CREST, l(3)j1D7, D-Titin, sam, l(3)Ca, 0020/01, Ket, D-titan, sal, D-Titin/Kettin, Titin, l(3)S002001, ket, D-titin, Salimus, Dtitin, l(3)62Ca" "IPR013783=Immunoglobulin-like fold, IPR001452=SH3 domain, IPR010939=Protein of unknown function DUF1136, IPR007110=Immunoglobulin-like domain, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG1915 16-Dec-15 2015_12 ENSMUSG00000061462 " embryonic stage | stage 16 , embryonic stage | stage >=11 , embryonic stage | stage >=14 , embryonic stage | stage 11 , embryonic stage | stage >=13 , embryonic stage | late , larval stage | first instar " " muscle attachment site

, somatic mesoderm

, pharyngeal muscle

, mesoderm

, embryonic/larval somatic muscle

, visceral mesoderm

, embryonic/larval muscle system

, embryonic/larval visceral muscle

, embryonic/larval salivary gland

" " embryonic stage | stage >11 , embryonic stage , embryonic stage | stage >=13 , embryonic stage | stage > 11 , larval stage , embryonic stage | late , adult stage " " myotube

, muscle attachment site

, embryonic/larval visceral muscle

, embryonic/larval somatic muscle

, muscle founder cell

, muscle cell

, fusion competent cell

, pharyngeal muscle

" DRSC08540 K -0.422860456 -1.149455837 -0.083156843 -1.151268307 -0.019766246 2.37647943 FBgn0027086 Aats-ile Isoleucyl-tRNA synthetase http://flybase.net/reports/FBgn0027086.html "FBgn0010728, FBgn0037159" protein_coding_gene "0005524=ATP binding, 0004822=isoleucine-tRNA ligase activity, 0002161=aminoacyl-tRNA editing activity" 0006428=isoleucyl-tRNA aminoacylation "0005737=cytoplasm, 0017101=aminoacyl-tRNA synthetase multienzyme complex" "l(3)00827, CG11471, IleRS, IRS" "IPR009008=Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080=Aminoacyl-tRNA synthetase, class 1a, anticodon-binding, IPR001412=Aminoacyl-tRNA synthetase, class I, conserved site, IPR002301=Isoleucine-tRNA ligase, IPR013155=Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729=Rossmann-like alpha/beta/alpha sandwich fold, IPR002300=Aminoacyl-tRNA synthetase, class Ia, IPR023586=Isoleucine-tRNA ligase, type 2" CG11471 16-Dec-15 2015_12 YBL076C(ILS1) WBGene00002152(iars-1) ENSXETG00000020903(IARS) ENSMUSG00000037851(Iars) ENSG00000196305(IARS) embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0266137 Dop1R2 Dopamine 1-like receptor 2 http://flybase.net/reports/FBgn0266137.html "FBgn0015129, FBgn0042212, FBgn0015741" protein_coding_gene "0008227=G-protein coupled amine receptor activity, 0004935=adrenergic receptor activity, 0004952=dopamine neurotransmitter receptor activity, 0001588=dopamine neurotransmitter receptor activity, coupled via Gs" "0001306=age-dependent response to oxidative stress, 0007191=adenylate cyclase-activating dopamine receptor signaling pathway, 1903223=positive regulation of oxidative stress-induced neuron death, 0007212=dopamine receptor signaling pathway" "0005886=plasma membrane, 0016021=integral component of membrane, 0005887=integral component of plasma membrane" "dopamine receptor in mushroom bodies, K13sc, D[[2]]-like receptor, DDR2, Dopamine receptor 2, DopD1, DopR2, DOPR2, Damb, DAMB DA receptor, dopamine-2 receptor, DOPR99B, DAMB, Dar2, DopR99B, DR2, DopRII, CG18741, CG7569" "IPR002233=Adrenoceptor family, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR017452=GPCR, rhodopsin-like, 7TM" CG18741 16-Dec-15 2015_12 "ENSDARG00000011317,ENSDARG00000069083,ENSDARG00000041173(zgc:103685),ENSDARG00000027638(LOC557259)" WBGene00016872(dop-4) "ENSMUSG00000045730(Adrb2),ENSMUSG00000035283(Adrb1),ENSMUSG00000031489(Adrb3)" ENSG00000171873(ADRA1D) " adult stage , larval stage " mushroom body

" larval stage , adult stage " " lobe system of mushroom body

, mushroom body beta-lobe

, mushroom body gamma-lobe

, mushroom body alpha-lobe

, mushroom body

" FBgn0041186 Slbp Stem-loop binding protein http://flybase.net/reports/FBgn0041186.html FBgn0039643 protein_coding_gene "0035613=RNA stem-loop binding, 0003729=mRNA binding" "0006398=histone mRNA 3'-end processing, 0008334=histone mRNA metabolic process, 0007076=mitotic chromosome condensation" "0005634=nucleus, 0005737=cytoplasm" "SLBP, CG11886, dSLBP, slbp, Stem Loop Binding Protein, dSLPB, stem-loop binding protein, stem loop binding protein, Stem-Loop Binding Protein" "IPR026502=Histone RNA stem-loop-binding protein SLBP1/SLBP2, IPR029344=Histone RNA hairpin-binding protein, RNA-binding domain" CG11886 16-Dec-15 2015_12 ENSDARG00000004926(si:dkey-102m7.2) WBGene00000411(cdl-1) ENSXETG00000003876(slbp) ENSMUSG00000004642(Slbp) ENSG00000163950(SLBP) " embryonic stage | stage 5-12 , embryonic stage | pre-blastoderm , embryonic stage | stage >=11 , embryonic stage -- adult stage , embryonic stage | stage >=13 " " organism | ubiquitous

, organism

, embryonic peripheral nervous system

, embryonic midgut

, embryonic central nervous system

" "lethal,recessive,viable,partially lethal - majority die,female sterile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage,maternal effect,partially lethal - majority live,wild-type" "nuclear chromosome,mitotic cell cycle" FBgn0023179 amon amontillado http://flybase.net/reports/FBgn0023179.html FBgn0004877 protein_coding_gene "0008233=peptidase activity, 0004252=serine-type endopeptidase activity" "0006508=proteolysis, 0035180=larval wandering behavior, 0016485=protein processing, 0035187=hatching behavior, 0002165=instar larval or pupal development, 0033500=carbohydrate homeostasis, 0016486=peptide hormone processing" "0005615=extracellular space, 0005576=extracellular region" "Amon, PC2, DMH#5, CG6438, Ppp, PPP, Prohormone processing protease, dPC2" "IPR023827=Peptidase S8, subtilisin, Asp-active site, IPR008979=Galactose-binding domain-like, IPR000209=Peptidase S8/S53 domain, IPR002884=Proprotein convertase, P, IPR009020=Proteinase inhibitor, propeptide, IPR023828=Peptidase S8, subtilisin, Ser-active site, IPR015500=Peptidase S8, subtilisin-related, IPR022398=Peptidase S8, subtilisin, His-active site" CG6438 16-Dec-15 2015_12 ENSDARG00000019451 YNL238W(KEX2) WBGene00001172(egl-3) ENSXETG00000003545(PCSK2) ENSMUSG00000027419(Pcsk2) ENSG00000125851(PCSK2) " embryonic stage | stage 17 , larval stage | first instar , larval stage | second instar , embryonic stage | stage >=15 , larval stage--adult stage , embryonic stage | stage >=16 " " larval labral segment sense organ

, larval brain | restricted

, ventral nerve cord | restricted

, embryonic frontal ganglion

, embryonic peripheral nervous system | restricted

, larval protocerebrum | restricted

, antenno-maxillary complex

, embryonic digestive system | restricted

, organism

, ring gland

, ventral nerve cord

segmentally repeated , embryonic brain

, embryonic/larval endocrine system | restricted

" "lethal,recessive,heat sensitive,small body,hypoactive,behavior defective,locomotor behavior defective" "larval head,leg,wing,wing disc,mesothoracic leg disc,metathoracic leg disc,prothoracic leg disc,ventral thoracic disc" FBgn0003886 ë±Tub85E ë±-Tubulin at 85E http://flybase.net/reports/FBgn0003886.html protein_coding_gene "0005200=structural constituent of cytoskeleton, 0005525=GTP binding, 0003924=GTPase activity" "0007094=mitotic spindle assembly checkpoint, 0051298=centrosome duplication, 0051258=protein polymerization, 0007052=mitotic spindle organization" "0005874=microtubule, 0045298=tubulin complex" "alpha85E, alphatubulin, alpha-Tubulin, alpha tubulin, alpha-Tubulin 85E, CG9476, tubulin, ALPHA 85E, 2t, a2t, alphaT, alpha-tubulin 85E, alpha-tubulin, alpha2tubulin, alphaTub, DTA3, alpha-Tub, alpha2-tubulin, alphaTub84E, alpha-Tub85E, alpha2, alpha2t, alphaTub2, alpha-tub, aTub85E, alpha85E-tub, T, Tub, alphaTub85E, alpha85E-tubulin" "IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR000217=Tubulin, IPR023123=Tubulin, C-terminal, IPR003008=Tubulin/FtsZ, GTPase domain, IPR002452=Alpha tubulin" CG9476 16-Dec-15 2015_12 "YML085C(TUB1),YML124C(TUB3)" WBGene00003175(mec-12) " larval stage | third instar , embryonic stage | >=8-12 hr , pupal stage , larval stage | second instar , larval stage--pupal stage , embryonic stage | 0-6 hr , larval stage | first instar , adult stage | male , larval stage , embryonic stage | 6-12 hr , prepupal stage , spermatogenesis && adult stage , embryonic stage | 2-21 hr " testis

" larval stage , embryonic stage | 16-20 hr , larval stage | third instar , spermatogenesis && adult stage " " imaginal disc

, dorsal mesothoracic disc

, testis

" "visible,male fertile" "wing,spermatid" DRSC16899 IE 2.743602807 -2.834850659 1.878470708 -2.002112452 -0.210120662 0.140310026 FBgn0262562 CG43102 http://flybase.net/reports/FBgn0262562.html "FBgn0038543, FBgn0038544" protein_coding_gene 0005089=Rho guanyl-nucleotide exchange factor activity 0035025=positive regulation of Rho protein signal transduction "CG14318, CG7397, FBgn0038543" "IPR000219=Dbl homology (DH) domain, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR011047=Quinonprotein alcohol dehydrogenase-like superfamily" CG43102 16-Dec-15 2015_12 ENSDARG00000063558(LOC100333630) WBGene00019832(R02F2.2) DRSC14797 K 0.634611321 -0.603085 0.187190951 -0.64125462 -1.854268152 -0.275655533 FBgn0261394 Prosë±3 Proteasome ë±3 subunit http://flybase.net/reports/FBgn0261394.html "FBgn0041193, FBgn0003150" protein_coding_gene "0004175=endopeptidase activity, 0004298=threonine-type endopeptidase activity" "0006511=ubiquitin-dependent protein catabolic process, 0090307=mitotic spindle assembly, 0007052=mitotic spindle organization, 0000022=mitotic spindle elongation, 0008283=cell proliferation, 0043161=proteasome-mediated ubiquitin-dependent protein catabolic process" "0019773=proteasome core complex, alpha-subunit complex, 0000502=proteasome complex, 0005875=microtubule associated complex, 0005839=proteasome core complex, 0005634=nucleus, 0005737=cytoplasm" "20s proteasome, PROS-29, Proteasome 20S alpha3 subunit, alpha3_dm, 20S proteasome, alpha-3, Alpha-3, Pros29, CG9327, pros29, alpha3, Prosalpha3, alpha-subunit of 20S proteasome, Proteasome 29kD subunit, Proteasome subunit alpha-type 4, Pros20S-alpha3, PSB3_DROME" "IPR001353=Proteasome, subunit alpha/beta, IPR016050=Proteasome beta-type subunit, conserved site, IPR023332=Proteasome A-type subunit, IPR000426=Proteasome alpha-subunit, N-terminal domain, IPR029055=Nucleophile aminohydrolases, N-terminal" CG9327 16-Dec-15 2015_12 ENSDARG00000045928(psma4) YGR135W(PRE9) WBGene00003924(pas-3) ENSXETG00000008877(psma4) ENSMUSG00000032301(Psma4) ENSG00000041357(PSMA4) DRSC04644 IE -1.444658099 -1.746599131 -3.564983288 -1.562301672 0.832298596 1.224119008 FBgn0036820 CG6852 http://flybase.net/reports/FBgn0036820.html FBgn0063224 protein_coding_gene "0015035=protein disulfide oxidoreductase activity, 0009055=electron carrier activity" "0045454=cell redox homeostasis, 0022008=neurogenesis" BcDNA:GH24739 "IPR002109=Glutaredoxin, IPR011899=Glutaredoxin, eukaryotic/virial, IPR014025=Glutaredoxin subgroup, IPR012336=Thioredoxin-like fold" CG6852 16-Dec-15 2015_12 ENSDARG00000042631(glrx2) "YDR513W(GRX2),YCL035C(GRX1)" WBGene00021331(glrx-10) ENSXETG00000004534(glrx2) ENSMUSG00000018196(Glrx2) ENSG00000023572(GLRX2) "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC10727 E -0.97519337 -0.180433884 1.623643401 -0.15989378 -0.469953825 -0.398453885 FBgn0267336 Glut4EF http://flybase.net/reports/FBgn0267336.html "FBgn0263097, FBgn0010943, FBgn0046785, FBgn0047268, FBpp0081627, FBtr0082149, FBpp0081625, FBtr0082147, FBgn0053975, FBgn0037767, FBgn0064791, FBgn0040537, FBgn0037768, FBgn0052469, FBgn0062980, FBgn0037771, FBgn0085389, FBgn0250818, FBgn0262953, FBgn0264088" protein_coding_gene 0046872=metal ion binding 0007476=imaginal disc-derived wing morphogenesis "CG32469, CG12802, BcDNA:GM06804, BcDNA:RE66512, CG34360, CG12804, CG33975, Glucose transporter 4 enhancer factor, stretch, BcDNA:GH25505, BcDNA:RH63124, D-Glut4EF, CG11676, CG43757, CG12805, stretched out" "IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG34360 16-Dec-15 2015_12 "ENSDARG00000060113(zgc:158367),ENSDARG00000024195(si:ch211-63o20.5),ENSDARG00000061718(si:ch211-203l9.3)" "ENSXETG00000021160(TEgg058g20.1),ENSXETG00000010417(ZNF704)" "ENSMUSG00000040209(Zfp704),ENSMUSG00000034522" "ENSG00000186918(ZNF395),ENSG00000164684(ZNF704)" DRSC14541 I 0.055133671 1.579810479 0.206630611 0.329188832 -0.575176756 -0.077960702 FBgn0002593 RpLP1 Ribosomal protein LP1 http://flybase.net/reports/FBgn0002593.html protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0006414=translational elongation" "0022625=cytosolic large ribosomal subunit, 0005840=ribosome" "rpP2, CG4087, Ribosomal-protein-A2, RpA2, Ribosomal protein A2, RpP2, rpA2, M(2)21C, LP1, RLA1_DROME, unnamed, rp21C, ACIDIC RIBOSOMAL PROTEIN LP1, chr2L:420593..420726, rpa2, M(2)21C1-2, Ribosomal protein P2, Rplp1, Minute(2)21C" IPR027534=Ribosomal protein L12 family CG4087 16-Dec-15 2015_12 ENSDARG00000021864(rplp1) "YDL081C(RPP1A),YDL130W(RPP1B)" WBGene00004409(rla-1) ENSXETG00000023754(rplp1) "ENSMUSG00000007892(Rplp1),ENSMUSG00000063324(Gm5244)" "ENSG00000137818(RPLP1),ENSG00000218175" "lethal,recessive,Minute,dominant,developmental rate defective,size defective" "chaeta,macrochaeta,adult heart" DRSC00783 IEK -3.291973223 -3.324180458 -1.588514139 -5.176080751 -0.417148183 1.831510531 FBgn0003141 pr purple http://flybase.net/reports/FBgn0003141.html FBgn0020600 protein_coding_gene 0003874=6-pyruvoyltetrahydropterin synthase activity "0006728=pteridine biosynthetic process, 0006729=tetrahydrobiopterin biosynthetic process" "CG16784, 38B.9, unnamed, anon-38Bb" "IPR022469=6-pyruvoyl tetrahydropterin synthase, histidine active site, IPR022470=6-pyruvoyl tetrahydropterin synthase, cysteine active site, IPR007115=6-pyruvoyl tetrahydropterin synthase/QueD family protein" CG16784 16-Dec-15 2015_12 ENSDARG00000045269(pts) WBGene00015010(ptps-1) ENSXETG00000008829(PTS) ENSMUSG00000032067(Pts) ENSG00000150787(PTS) embryonic stage -- adult stage "lethal,recessive,eye color defective,visible" pigment cell DRSC03596 IE 1.67503972 1.071070612 2.735635247 -1.293602158 0.021888337 -0.692367585 FBgn0050373 CG30373 http://flybase.net/reports/FBgn0050373.html FBgn0064787 protein_coding_gene BcDNA:RH67738 IPR029160=CCSMST1 family CG30373 16-Dec-15 2015_12 "viable,visible" trichogen cell DRSC29668 K -0.589698746 0.387429435 0.965165564 0.584324136 0.165157606 1.587392624 FBgn0259146 CG42261 http://flybase.net/reports/FBgn0259146.html "FBgn0039399, FBgn0039400" protein_coding_gene 0008168=methyltransferase activity 0008152=metabolic process "CG14541, CG8968" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR013216=Methyltransferase type 11" CG42261 16-Dec-15 2015_12 DRSC16464 IE 0.571896469 -1.855635129 1.531879575 -1.728271517 0.512328221 0.4268913 FBgn0000182 BicC Bicaudal C http://flybase.net/reports/FBgn0000182.html protein_coding_gene "0003729=mRNA binding, 0005515=protein binding, 0003723=RNA binding" "0007067=mitotic nuclear division, 0000226=microtubule cytoskeleton organization, 0030036=actin cytoskeleton organization, 0048477=oogenesis, 0007319=negative regulation of oskar mRNA translation, 0007297=ovarian follicle cell migration" 0005887=integral component of plasma membrane "Bic-C, br34, CG4824, Bicaudal-C, Dromel_CG4824_FBtr0080804_bicc_mORF, l(2)br34, BICC, BG:DS00913.2" "IPR004087=K Homology domain, IPR001660=Sterile alpha motif domain, IPR013761=Sterile alpha motif/pointed domain, IPR004088=K Homology domain, type 1" CG4824 16-Dec-15 2015_12 "ENSDARG00000027227,ENSDARG00000061682(LOC568201)" WBGene00000246(bcc-1) ENSXETG00000005117(BICC1) ENSMUSG00000014329(Bicc1) ENSG00000122870(BICC1) " adult stage | female , adult stage && oogenesis stage | stage S8-9 , adult stage && oogenesis stage | stage >=S10 , embryonic stage | 0-4 hr , adult stage | male , adult stage && oogenesis stage | stage S1-7 , adult stage && oogenesis stage " " oocyte | anterior

, nurse cell

, oocyte

, germarium region 2a && germarium region 2b && germarium region 3

, germarium region 2a && germarium region 2b && germarium region 3

" " adult stage && oogenesis stage | stage >=S10 , adult stage && oogenesis stage | stage S3-10 " " nurse cell

, oocyte

" "lethal,maternal effect,female sterile,dominant,lethal - all die before end of embryonic stage,partially,some die during embryonic stage,recessive,viable" "dorsal appendage,follicle cell,microtubule & oocyte,nurse cell,maternal effect,pole cell,embryonic head,oocyte,egg,embryo" FBgn0004839 otk off-track http://flybase.net/reports/FBgn0004839.html FBgn0082205 protein_coding_gene "0005524=ATP binding, 0042803=protein homodimerization activity, 0004872=receptor activity, 0046982=protein heterodimerization activity, 0030215=semaphorin receptor binding, 0004713=protein tyrosine kinase activity, 0004714=transmembrane receptor protein tyrosine kinase activity, 0050839=cell adhesion molecule binding, 0017147=Wnt-protein binding, 0004672=protein kinase activity" "0007411=axon guidance, 0031290=retinal ganglion cell axon guidance, 0007155=cell adhesion, 0048803=imaginal disc-derived male genitalia morphogenesis, 0048804=imaginal disc-derived female genitalia morphogenesis, 0090090=negative regulation of canonical Wnt signaling pathway, 0035260=internal genitalia morphogenesis, 0006468=protein phosphorylation" "0005886=plasma membrane, 0016021=integral component of membrane" "Dtkr, OFT/TRK, Tk48D, CG8967, Tyrosine kinase at 48D, OTK, Trk48D, Otk, CT25769, Dtrk, Off-track, IGGtyk, anon-WO2004063362.81, dTrk, off track, DTrk" "IPR013098=Immunoglobulin I-set, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR007110=Immunoglobulin-like domain" CG8967 16-Dec-15 2015_12 ENSDARG00000011863 ENSMUSG00000023972(Ptk7) ENSG00000112655(PTK7) embryonic stage&&pupal stage " embryonic stage | stage 13 , embryonic stage | stage 11 , embryonic stage | late , embryonic stage | stage 12 , embryonic stage | stage 7 , embryonic stage | stage 7-11 , embryonic stage | stage 12-17 " " embryonic/larval hindgut

, posterior midgut proper primordium

, embryonic/larval midgut

, epidermis | restricted

, posterior commissure

, visceral mesoderm

, maxillary segment

, peripheral nervous system | restricted

, ventral nerve cord

, epidermis | segmentally repeated

, neuron

, proctodeum | primordium

, cell body

, cephalic furrow

, anterior midgut proper primordium

, neuroblast

, neuron

, procephalic segment

, anterior commissure

" "viable,female sterile,partially lethal - majority die,wild-type,visible,planar polarity defective" "oviduct,photoreceptor cell R2 & axon & larva[-],photoreceptor cell R3 & axon & larva[-],photoreceptor cell R4 & axon & larva[-],photoreceptor cell R5 & axon & larva[-],photoreceptor cell R6 & axon & larva[-],axonelav.PLu,intersegmental nerve,abdominal segmental nerve,axon,eye photoreceptor cell & axon & larva | somatic clone,photoreceptor cell R1 & axon & larva | somatic clone,photoreceptor cell R2 & axon & larva | somatic clone,photoreceptor cell R3 & axon & larva | somatic clone,photoreceptor cell R4 & axon & larva | somatic clone,photoreceptor cell R5 & axon & larva | somatic clone,photoreceptor cell R6 & axon & larva | somatic clone,lamina & glial cell & larva | somatic clone,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,medulla,somatic clone,denticle belt,ectopic,embryonic/first instar larval cuticle,wing margin,wing hair" FBgn0015583 Acp29AB Accessory gland protein 29AB http://flybase.net/reports/FBgn0015583.html protein_coding_gene "0030246=carbohydrate binding, 0005179=hormone activity, 0005534=galactose binding" "0046692=sperm competition, 0007321=sperm displacement, 0032504=multicellular organism reproduction, 0045297=post-mating behavior, 0046693=sperm storage" "0005576=extracellular region, 0005615=extracellular space" "Acp29B, Acp29, Accessory gland-specific peptide 29AB, Acp29AB-II, Accessory gland protein 29AB, CG17797, AC 004423B, accessory gland protein, AC004423b" "IPR001304=C-type lectin, IPR016186=C-type lectin-like, IPR016187=C-type lectin fold" CG17797 16-Dec-15 2015_12 "ENSDARG00000068221(LOC566971),ENSDARG00000054202(hbl4),ENSDARG00000068222,ENSDARG00000068220(hbl3),ENSDARG00000070813" WBGene00019328(clec-149) ENSXETG00000001204(COLEC11) "ENSMUSG00000008874(Clec3a),ENSMUSG00000025784(Clec3b),ENSMUSG00000004473(Clec11a)" ENSG00000163815(CLEC3B) adult stage | male " male accessory gland main cell

, male accessory gland

" "viable,visible,partially lethal - majority die,some die during pupal stage,fertile" trichogen cell FBgn0011584 Trp1 Translocation protein 1 http://flybase.net/reports/FBgn0011584.html FBgn0011838 protein_coding_gene 0008565=protein transporter activity 0006614=SRP-dependent cotranslational protein targeting to membrane "0012505=endomembrane system, 0016021=integral component of membrane, 0005784=Sec61 translocon complex" "Dtrp1, CG4758, sec62, Tp1" IPR004728=Translocation protein Sec62 CG4758 16-Dec-15 2015_12 ENSDARG00000019951(sec62) WBGene00007683(C18E9.2) ENSXETG00000009213(SEC62) ENSMUSG00000027706(Sec62) ENSG00000008952(SEC62) " spermatogenesis && adult stage , adult stage | female , oogenesis stage && adult stage | female , embryonic stage -- adult stage , adult stage | male " " testis

, ovary

, ejaculatory duct

, male accessory gland

" "visible,uncoordinated,viable,body color defective" "wing,embryonic/larval hemocyte | third instar larval stage,trichogen cell,mesothoracic tergum" FBgn0003248 Rh2 Rhodopsin 2 http://flybase.net/reports/FBgn0003248.html protein_coding_gene 0008020=G-protein coupled photoreceptor activity "0007186=G-protein coupled receptor signaling pathway, 0007602=phototransduction, 0007601=visual perception" 0016021=integral component of membrane "Rhodopsin, rhodopsin, DMELRH2, RH2, Rh, rh2, Dm Rh2, CG16740" "IPR017452=GPCR, rhodopsin-like, 7TM, IPR027430=Visual pigments (opsins) retinal binding site, IPR000276=G protein-coupled receptor, rhodopsin-like, IPR001760=Opsin, IPR001735=Opsin RH1/RH2" CG16740 16-Dec-15 2015_12 "ENSDARG00000007553(opn4l),ENSDARG00000053929(LOC566133),ENSDARG00000022098(opn4a),ENSDARG00000051908(si:dkeyp-100d11.3)" ENSXETG00000019216(OPN4) ENSMUSG00000021799(Opn4) ENSG00000122375(OPN4) " adult stage , spermatogenesis && adult stage " " ocellus

, adult head

, photoreceptor cell R8

, testis

" adult stage " photoreceptor cell R1--6

, photoreceptor cell R1..6

{ $ ninaA* } " "viable,visible" "chaeta,supernumerary" FBgn0034534 maf-S maf-S http://flybase.net/reports/FBgn0034534.html "FBgn0020275, FBgn0027740" protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0042803=protein homodimerization activity, 0046982=protein heterodimerization activity" "0035071=salivary gland cell autophagic cell death, 0006351=transcription, DNA-templated, 0006366=transcription from RNA polymerase II promoter, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048102=autophagic cell death, 0060322=head development" 0005634=nucleus "CG9954, anon-EST:Posey173, MafS, Maf, DM31, maf2, DM19, Maf-S" "IPR008917=Transcription factor, Skn-1-like, DNA-binding domain, IPR004827=Basic-leucine zipper domain, IPR004826=Basic leucine zipper domain, Maf-type, IPR024874=Transcription factor Maf" CG9954 16-Dec-15 2015_12 "ENSDARG00000030791(mafg2),ENSDARG00000018109(LOC100330983),ENSDARG00000033709(mafk),ENSDARG00000028957(maff)" WBGene00077521(F45H11.6) "ENSXETG00000005386(MAFG),ENSXETG00000006355(MAFF),ENSXETG00000018118(MAFK)" "ENSMUSG00000018143(Mafk),ENSMUSG00000051510(Mafg),ENSMUSG00000042622(Maff)" "ENSG00000198517(MAFK),ENSG00000197063(MAFG),ENSG00000218788,ENSG00000185022(MAFF)" "oxidative stress response defective,viable,chemical sensitive" "mouth hooks,supernumerary,lateral process,median tooth,embryonic/larval pharynx,ventral" DRSC07348 K 0.629538968 -1.224037685 0.312948847 0.277857815 1.146588183 1.744531212 FBgn0087035 AGO2 Argonaute 2 http://flybase.net/reports/FBgn0087035.html "FBgn0046812, FBgn0036508, FBgn0040803, FBgn0004891" protein_coding_gene "0005515=protein binding, 0004521=endoribonuclease activity, 0035197=siRNA binding, 0003743=translation initiation factor activity" "0045071=negative regulation of viral genome replication, 0007349=cellularization, 0070868=heterochromatin organization involved in chromatin silencing, 0006413=translational initiation, 0035195=gene silencing by miRNA, 0035087=siRNA loading onto RISC involved in RNA interference, 0016246=RNA interference, 0009047=dosage compensation by hyperactivation of X chromosome, 0033227=dsRNA transport, 0035190=syncytial nuclear migration, 0010526=negative regulation of transposition, RNA-mediated, 0098586=cellular response to virus, 0007279=pole cell formation, 0030423=targeting of mRNA for destruction involved in RNA interference, 0007367=segment polarity determination, 0030422=production of siRNA involved in RNA interference, 0035071=salivary gland cell autophagic cell death, 0051607=defense response to virus, 0048102=autophagic cell death" "0016442=RISC complex, 0070578=RISC-loading complex, 0005737=cytoplasm, 0005829=cytosol" "CG7439, ago-2, argonaute-2, DmAgo2, argonaute, Argonaute, ago, dAGO2, ARGONAUTE2, argonaute2, CG13452, dAgo2, Ago-2, AG02, Argonaute-2, Argonaute2, argonaute 2, AGO 2, Ago2, Dm Ago2, eIF2C2, ago2" "IPR003165=Piwi domain, IPR012337=Ribonuclease H-like domain, IPR003100=PAZ domain, IPR014811=Argonaute, linker 1 domain" CG7439 16-Dec-15 2015_12 DRSC10847 IE -2.847199926 -4.680947 -4.670712475 -3.774338879 0.177515034 0.750577986 FBgn0005670 Cyp4d1 Cytochrome P450-4d1 http://flybase.net/reports/FBgn0005670.html FBgn0010221 protein_coding_gene "0005506=iron ion binding, 0009055=electron carrier activity, 0020037=heme binding, 0016705=oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 0055114=oxidation-reduction process "0043231=intracellular membrane-bounded organelle, 0005811=lipid particle, 0016020=membrane" "Cyt-P450-4D1, cyp4d1, Cytochrome P450 4D1, P450 CYPD1, 4d1, CG3656, P450, CYP4D1, P-450, EG:87B1.1, CYP6D1, Cyp4D1, cytochrome P450" "IPR001128=Cytochrome P450, IPR017972=Cytochrome P450, conserved site, IPR002401=Cytochrome P450, E-class, group I" CG3656 16-Dec-15 2015_12 YMR015C(ERG5) " embryonic stage -- adult stage , larval stage | third instar " viable DRSC17694 K -1.311069076 -0.031261123 0.202148543 0.085377742 1.529260967 -0.04008493 FBgn0033260 Cul4 Cullin 4 http://flybase.net/reports/FBgn0033260.html protein_coding_gene 0031625=ubiquitin protein ligase binding "0045732=positive regulation of protein catabolic process, 0007095=mitotic G2 DNA damage checkpoint, 0016567=protein ubiquitination, 0042787=protein ubiquitination involved in ubiquitin-dependent protein catabolic process, 0051533=positive regulation of NFAT protein import into nucleus, 0007307=eggshell chorion gene amplification" "0080008=Cul4-RING E3 ubiquitin ligase complex, 0000152=nuclear ubiquitin ligase complex" "cul-4, Cullin-4, cul4, CG8711, Cul-4, Cullin4, DMcul-4, Cullin 4, CUL4, dCul4, cullin-4, Cul4" "IPR016157=Cullin, conserved site, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR019559=Cullin protein, neddylation domain, IPR001373=Cullin, N-terminal, IPR016159=Cullin repeat-like-containing domain, IPR016158=Cullin homology" CG8711 16-Dec-15 2015_12 ENSDARG00000060510(cul4b) YGR003W(CUL3) "ENSXETG00000004474(CUL4B),ENSXETG00000001957(TEgg006j10.1)" "ENSMUSG00000031095(Cul4b),ENSMUSG00000031446(Cul4a)" "ENSG00000158290(CUL4B),ENSG00000139842(CUL4A)" "cell lethalcell lethal,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,cell shape defective,decreased cell number,visible,partially lethal - majority die,some die during pupal stage,decreased cell death" "eye,somatic clone,follicle cell,mesothoracic tergum" DRSC07243 IE -1.020041778 -1.803892241 -0.672070867 -1.729769066 0.305541001 -0.442842379 FBgn0004780 Ccp84Ad Ccp84Ad http://flybase.net/reports/FBgn0004780.html protein_coding_gene "0005214=structural constituent of chitin-based cuticle, 0008010=structural constituent of chitin-based larval cuticle" "0040003=chitin-based cuticle development, 0032504=multicellular organism reproduction" "0005615=extracellular space, 0031012=extracellular matrix" "unnamed, BG:DS00004.4, cc5, CG2341, Ccp, DmelCcp84Ad, cuticle cluster 5" "IPR031311=Chitin-binding type R&R consensus, IPR000618=Insect cuticle protein" CG2341 16-Dec-15 2015_12 DRSC12589 E -0.440994131 0.96515886 -0.091688706 1.917354485 0.675927897 -0.119296188 FBgn0036607 CG13059 http://flybase.net/reports/FBgn0036607.html protein_coding_gene CG13059 16-Dec-15 2015_12 viable DRSC09942 K 0.381238094 -0.706746584 -0.337873852 -0.300640312 1.88276495 -0.215007721 FBgn0010348 Arf79F ADP ribosylation factor at 79F http://flybase.net/reports/FBgn0010348.html protein_coding_gene "0003924=GTPase activity, 0005525=GTP binding" "0045807=positive regulation of endocytosis, 0007155=cell adhesion, 0032011=ARF protein signal transduction, 0006892=post-Golgi vesicle-mediated transport, 0008360=regulation of cell shape, 0016197=endosomal transport, 0048749=compound eye development, 0007269=neurotransmitter secretion, 0006471=protein ADP-ribosylation, 1902036=regulation of hematopoietic stem cell differentiation, 0010883=regulation of lipid storage, 0048488=synaptic vesicle endocytosis" "0005795=Golgi stack, 0043231=intracellular membrane-bounded organelle" "Dm Arf79F, ADP ribosylation factor 79F, arf1, ADP ribosylation factor at 79F, Arf1, ADP-ribosylation factor 1, unnamed, Arf, dARF79F, CG8385, dArf1, Darf1, ARF-1, ARF1_DROME, dARFI, P61209, d-Arf1, Arf79f, ARF1" "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR005225=Small GTP-binding protein domain, IPR024156=Small GTPase superfamily, ARF type, IPR006689=Small GTPase superfamily, ARF/SAR type" CG8385 16-Dec-15 2015_12 "ENSDARG00000016393(arf1l),ENSDARG00000014763(arf2)" "YDL192W(ARF1),YDL137W(ARF2)" WBGene00000182(arf-1.2) "ENSXETG00000013916(BC061435.1),ENSXETG00000014250(arf1)" ENSMUSG00000048076(Arf1) ENSG00000143761(ARF1) adult stage "viable,fertile,lethal,cell cycle defective,endocytosis defective" "embryonic myoblast,rhabdomere R7,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage,secondary lobe of embryonic/larval lymph gland | third instar larval stage,posterior signalling centre of lymph gland primary lobe | third instar larval stage,cortical zone of lymph gland primary lobe | third instar larval stage,embryonic/larval hemocyte | second instar larval stage,embryonic/larval hemocyte | third instar larval stage,posterior signalling centre of lymph gland primary lobe | first instar larval stage,posterior signalling centre of lymph gland primary lobe | second instar larval stage,lamellocyte,embryonic/larval hemocyte,eye" DRSC11606 E -0.757370785 0.09177419 0.930836857 -1.873575562 -0.489828235 -0.090853934 FBgn0020251 sfl sulfateless http://flybase.net/reports/FBgn0020251.html FBgn0010820 protein_coding_gene "0015016=[heparan sulfate]-glucosamine N-sulfotransferase activity, 0016787=hydrolase activity" "0007474=imaginal disc-derived wing vein specification, 0007509=mesoderm migration involved in gastrulation, 0015012=heparan sulfate proteoglycan biosynthetic process, 0007427=epithelial cell migration, open tracheal system, 0060828=regulation of canonical Wnt signaling pathway, 0045570=regulation of imaginal disc growth, 0090097=regulation of decapentaplegic signaling pathway, 0016055=Wnt signaling pathway, 0006790=sulfur compound metabolic process, 0007507=heart development, 0048488=synaptic vesicle endocytosis, 0007428=primary branching, open tracheal system, 0007367=segment polarity determination, 0008543=fibroblast growth factor receptor signaling pathway, 0007283=spermatogenesis, 0015014=heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, 0048312=intracellular distribution of mitochondria, 0008587=imaginal disc-derived wing margin morphogenesis, 0006024=glycosaminoglycan biosynthetic process, 0007166=cell surface receptor signaling pathway" "0005622=intracellular, 0005783=endoplasmic reticulum, 0000137=Golgi cis cisterna" "sulfateless, NDST, l(3)03844, diet-wingless, dw, CT24567, unnamed, Sulfateless, Sfl, lincRNA.S4253, CG8339" "IPR000863=Sulfotransferase domain, IPR021930=Heparan sulphate-N-deacetylase, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG8339 16-Dec-15 2015_12 ENSDARG00000060678(LOC798226) WBGene00002028(hst-1) "ENSXETG00000009997(NDST2),ENSXETG00000015804(ndst4),ENSXETG00000010566(NDST4),ENSXETG00000004033(NDST3)" "ENSMUSG00000039308(Ndst2),ENSMUSG00000054008(Ndst1),ENSMUSG00000027971(Ndst4),ENSMUSG00000027977(Ndst3)" "ENSG00000166507(NDST2),ENSG00000070614(NDST1),ENSG00000138653(NDST4),ENSG00000164100(NDST3)" embryonic stage | early "viable,fertile,lethal,recessive,fully,rescuable maternal effect,visible,somatic clone,increased mortality during development,neurophysiology defective,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,segment polarity phenotype,partially lethal - majority die,size defective" "embryonic/first instar larval cuticle,sensory mother cell,cuticle,denticle belt,mesoderm,germline clone,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval ganglionic branch,wing margin,somatic clone,synapse,imaginal tracheoblast,embryonic epidermis,stomatogastric nervous system,midgut constriction 2,embryo,mesothoracic tergum,anterior crossvein,wing disc" DRSC08830 K 1.357098144 1.139069118 0.443828557 -0.21373835 1.588698524 -0.311611419 FBgn0005778 PpD5 Protein phosphatase D5 http://flybase.net/reports/FBgn0005778.html "FBgn0034682, FBgn0044777" protein_coding_gene 0004722=protein serine/threonine phosphatase activity 0006470=protein dephosphorylation "0005634=nucleus, 0005737=cytoplasm" "PP1-like, D5, anon-WO0140519.107, CG10138, protein phosphatase from PCR fragment D5" "IPR006186=Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052=Metallo-dependent phosphatase-like, IPR004843=Calcineurin-like phosphoesterase domain, apaH type" CG10138 16-Dec-15 2015_12 viable DRSC04641 I 1.609499959 -0.254151158 0.207311173 0.301575884 0.170236227 0.785042572 FBgn0031859 CG17377 http://flybase.net/reports/FBgn0031859.html "FBgn0044599, FBgn0046239" protein_coding_gene "BEST:LP06279, anon-WO0140519.32" CG17377 16-Dec-15 2015_12 DRSC21811 I 1.730693102 -1.899209258 0.79080497 0.4504855 0.171731521 0.525861543 FBgn0262111 f forked http://flybase.net/reports/FBgn0262111.html "FBgn0000630, FBgn0030835" protein_coding_gene 0003779=actin binding "0035317=imaginal disc-derived wing hair organization, 0051017=actin filament bundle assembly, 0009913=epidermal cell differentiation, 0008407=chaeta morphogenesis, 0007605=sensory perception of sound, 0048800=antennal morphogenesis, 0035017=cuticle pattern formation" 0031941=filamentous actin "unnamed, CG42864, CG5424, X1, CG12996, Forked" "IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG42864 16-Dec-15 2015_12 ENSXETG00000001165(ESPN) "ENSMUSG00000028943(Espn),ENSMUSG00000049515(Espnl)" "ENSG00000187017(ESPN),ENSG00000116219" " embryonic stage , pupal stage " DRSC20331 EK 0.442633592 -0.117204583 1.778375258 0.223447583 -1.545373741 -2.023087572 FBgn0028527 CG18507 http://flybase.net/reports/FBgn0028527.html FBgn0032531 protein_coding_gene "bg:ds01368, BG:DS01368.1, DS01368.1" IPR028054=Protein of unknown function DUF4481 CG18507 16-Dec-15 2015_12 WBGene00016131(C26B9.1) viable DRSC01334 K 0.05734465 -0.082186422 1.069166715 0.360276102 -1.625196689 1.347907389 FBgn0052070 CG32070 http://flybase.net/reports/FBgn0052070.html protein_coding_gene 16-Dec-15 2015_12 DRSC10148 IEK 0.223181158 -2.118598558 -1.258075065 -2.668143016 -1.862733662 -1.488758605 FBgn0011476 l(3)neo43 lethal (3) neo43 http://flybase.net/reports/FBgn0011476.html FBgn0038314 protein_coding_gene 0031966=mitochondrial membrane CG14865 IPR020164=Cytochrome c oxidase assembly protein COX16 CG14865 16-Dec-15 2015_12 ENSDARG00000039136(cox16) ENSG00000133983(COX16) "lethal,recessive,viable" DRSC14988 K 0.003641715 0.908018133 -0.73460815 0.067062258 0.546300075 -1.522109216 FBgn0010905 Spn Spinophilin http://flybase.net/reports/FBgn0010905.html "FBgn0045360, FBgn0045813, FBgn0052295, FBgn0024370, FBgn0035350, FBgn0063195" protein_coding_gene 0008157=protein phosphatase 1 binding "0042048=olfactory behavior, 0002121=inter-male aggressive behavior" "0070938=contractile ring, 0045179=apical cortex" "BcDNA:GM16129, spn, c62E-5, d-spinophilin, EL62, E62, l(3)06911, CG16757" "IPR001478=PDZ domain, IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain" CG16757 16-Dec-15 2015_12 "ENSMUSG00000038976(Ppp1r9b),ENSMUSG00000032827(Ppp1r9a)" "ENSG00000108819,ENSG00000158528(PPP1R9A)" "behavior defective,recessive,viable,smell perception defective,partially lethal - majority die" DRSC08490 E 0.120464464 0.313313547 4.179139705 0.021906354 -0.865887499 0.174365904 FBgn0039404 CG14543 http://flybase.net/reports/FBgn0039404.html protein_coding_gene 0022008=neurogenesis IPR019398=Pre-rRNA-processing protein TSR2 CG14543 16-Dec-15 2015_12 ENSDARG00000005772(dt1p1a10l) ENSMUSG00000025264(Tsr2) ENSG00000158526(TSR2) "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" DRSC26647 K -0.408115862 -0.993111832 0.891010119 -0.499351168 1.762681366 0.001220556 FBgn0022213 Cas CAS/CSE1 segregation protein http://flybase.net/reports/FBgn0022213.html "FBgn0027058, FBgn0027064" protein_coding_gene "0008536=Ran GTPase binding, 0008262=importin-alpha export receptor activity" "0006915=apoptotic process, 0022008=neurogenesis, 0006606=protein import into nucleus, 0051533=positive regulation of NFAT protein import into nucleus, 0006909=phagocytosis, 0006611=protein export from nucleus" "0005634=nucleus, 0005737=cytoplasm, 0005829=cytosol, 0005654=nucleoplasm, 0005635=nuclear envelope" "Dcas, CAS, Importin-alpha re-exporter, dcas, l(2)k03902, cas, BcDNA:LD14270, CG13281" "IPR013713=Exportin/Importin, Cse1-like, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR005043=CAS/CSE, C-terminal, IPR001494=Importin-beta, N-terminal domain" CG13281 16-Dec-15 2015_12 ENSDARG00000006963(LOC100331234) YGL238W(CSE1) WBGene00002079(xpo-2) ENSXETG00000001784(CSE1L) ENSMUSG00000002718(Cse1l) ENSG00000124207(CSE1L) "lethal,recessive,somatic clone,female sterile,heat sensitive,wild-type,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,visible" "egg,microchaeta,macrochaeta,thecogen cell,eo neuron,tormogen cell,ectopic,embryonic/larval neuroblast,ganglion mother cell,tergite" DRSC03287 IEK -2.375873067 -2.443974 -0.865394335 -1.761913231 1.631364371 -0.286179869 FBgn0052080 CG32080 http://flybase.net/reports/FBgn0052080.html protein_coding_gene 16-Dec-15 2015_12 DRSC09074 K -1.215343591 -0.162650678 -0.460372234 1.008727845 1.822830356 1.862328418 FBgn0051358 CG31358 http://flybase.net/reports/FBgn0051358.html "FBgn0037982, FBgn0037983, FBgn0037984" protein_coding_gene 0005887=integral component of plasma membrane "CG17424, CG18141, CG18142" "IPR001972=Stomatin family, IPR001107=Band 7 protein" CG31358 16-Dec-15 2015_12 viable DRSC15308 E 0.197633403 1.425730584 1.801352901 0.205245976 -0.185364587 -0.237611095 FBgn0031249 CG11911 http://flybase.net/reports/FBgn0031249.html protein_coding_gene 0004252=serine-type endopeptidase activity 0006508=proteolysis SP103 "IPR001254=Serine proteases, trypsin domain, IPR001314=Peptidase S1A, chymotrypsin-type, IPR018114=Peptidase S1, trypsin family, active site, IPR009003=Peptidase S1, PA clan" CG11911 16-Dec-15 2015_12 viable DRSC27293 K -0.274163179 -0.33887127 -0.230535886 0.379632985 -0.677376771 -1.822196159 FBgn0033541 CG12934 http://flybase.net/reports/FBgn0033541.html protein_coding_gene CG12934 16-Dec-15 2015_12 viable DRSC06247 E -0.972267787 0.283259047 -0.498095649 2.148202277 1.050904829 0.399895067 FBgn0010053 Jheh1 Juvenile hormone epoxide hydrolase 1 http://flybase.net/reports/FBgn0010053.html "FBgn0034404, FBgn0046304" protein_coding_gene "0004301=epoxide hydrolase activity, 0008096=juvenile hormone epoxide hydrolase activity, 0033961=cis-stilbene-oxide hydrolase activity" 0006719=juvenile hormone catabolic process "Juvenile hormone epoxide hydrolase, BEST:GH06241, microsomal apoxide hydrolase, 142196_at, CG15101, JH-epoxide hydrolase, JHEH, JH, Jheh" "IPR010497=Epoxide hydrolase, N-terminal, IPR000639=Epoxide hydrolase-like, IPR029058=Alpha/Beta hydrolase fold, IPR016292=Epoxide hydrolase" CG15101 16-Dec-15 2015_12 ENSDARG00000042854(ephx1) WBGene00020909(W01A11.1) ENSXETG00000022654(EPHX1) ENSMUSG00000038776(Ephx1) ENSG00000143819(EPHX1) "viable,fertile" DRSC06529 I 0.708921415 -1.95770292 -1.082711975 -0.088206565 -0.547520244 -0.69024549 FBgn0001104 Gë±i G protein ë± i subunit http://flybase.net/reports/FBgn0001104.html protein_coding_gene "0001664=G-protein coupled receptor binding, 0003924=GTPase activity, 0005515=protein binding, 0031683=G-protein beta/gamma-subunit complex binding, 0003677=DNA binding, 0005525=GTP binding, 0004871=signal transducer activity" "0060857=establishment of glial blood-brain barrier, 0008356=asymmetric cell division, 0051294=establishment of spindle orientation, 0055059=asymmetric neuroblast division, 0045167=asymmetric protein localization involved in cell fate determination, 0019991=septate junction assembly, 0019722=calcium-mediated signaling, 0032880=regulation of protein localization, 0007186=G-protein coupled receptor signaling pathway, 0030866=cortical actin cytoskeleton organization, 0007419=ventral cord development, 0007188=adenylate cyclase-modulating G-protein coupled receptor signaling pathway" "0045179=apical cortex, 0005886=plasma membrane, 0005938=cell cortex, 0005834=heterotrimeric G-protein complex, 0031234=extrinsic component of cytoplasmic side of plasma membrane" "G-ialpha65a, Gi, Gi-alpha, i, Galpha[[i]], G protein alphai subunit 65A, G protein alpha-subunit, G protein alphao subunit 65A, G protein I a-subunit 65A, Galpha65A, G protein alpha subunit, Galpha i, G-ialpha65A, Gai, Gi/0, Galphai, G[[i]]alpha, G-alpha-65A, CG10060, Galpha[[i]]65A, G[[i]], DGalpha1, DG[[alpha1]], G-oalpha65A, Galphaiota65A, G-ia65A, G protein alpha o subunit 65A, Galpha[[i65A]], G[[alphai]], Gialpha" "IPR001408=G-protein alpha subunit, group I, IPR001019=Guanine nucleotide binding protein (G-protein), alpha subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR011025=G protein alpha subunit, helical insertion" CG10060 16-Dec-15 2015_12 "ENSDARG00000021647(gnai1),ENSDARG00000044760(gnaia),ENSDARG00000030644(gnai3),ENSDARG00000018174(gnai2l),ENSDARG00000017294(gnai2)" YHR005C(GPA1) WBGene00001678(gpa-16) "ENSXETG00000025696(GNAI1),ENSXETG00000002003(gnai3)" "ENSMUSG00000057614(Gnai1),ENSMUSG00000000001(Gnai3),ENSMUSG00000032562(Gnai2)" "ENSG00000127955(GNAI1),ENSG00000065135(GNAI3),ENSG00000114353(GNAI2)" " embryonic stage | early--P , adult stage && oogenesis stage , embryonic stage , embryonic stage&&pupal stage , embryonic stage -- adult stage " " organism

, oocyte

, nurse cell

" " larval stage , adult stage , embryonic stage | pre-blastoderm , embryonic stage | stage >=14 , adult stage && oogenesis stage | stage >=S10B , embryonic stage | >stage 15 " " subesophageal ganglion | restricted

, nerve terminal &&of photoreceptor cell

, organism

, ocellar nerve | proximal

, cardioblast | presumptive

, follicle cell

, ring gland

, neuropil

, cardioblast

, antennal glomerulus

, retina

, adult brain cortex

, ocellus retinula cell

" "cell polarity defective,planar polarity defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,viable,fertile,wild-type,germline clone,locomotor behavior defective" "embryonic neuroblast & spindlemat.ë±Tub67C.THsimVP16,embryonic neuroblast,sensory mother cell & spindle-109-68,medial triple row,lateral cord surface glia & nucleusrepo,cell cortex & cortical cytoskeletonrepo,neuroblast,spindle pole centrosome & astral microtubule-P309,mitotic domain 9 & epithelial cell,RP2sib neuron,RP2 motor neuron,spindle & neuroblast,germline clone,EL neuron,spindle & external sensory organ precursor cell I,chaeta" FBgn0015778 rin rasputin http://flybase.net/reports/FBgn0015778.html FBgn0038164 protein_coding_gene "0003729=mRNA binding, 0017124=SH3 domain binding, 0000166=nucleotide binding, 0005515=protein binding, 0003676=nucleic acid binding" "0008069=dorsal/ventral axis specification, ovarian follicular epithelium, 0007265=Ras protein signal transduction, 0045571=negative regulation of imaginal disc growth, 0001752=compound eye photoreceptor fate commitment, 0006810=transport, 0010628=positive regulation of gene expression, 0000398=mRNA splicing, via spliceosome, 0016318=ommatidial rotation" "0005737=cytoplasm, 0005829=cytosol, 0071011=precatalytic spliceosome, 0030529=ribonucleoprotein complex, 0005811=lipid particle, 0071013=catalytic step 2 spliceosome" "cg9412, Next to squid, Rasputin, Nts, CG9412, rasp, RIN, Rin" "IPR000504=RNA recognition motif domain, IPR002075=Nuclear transport factor 2, IPR018222=Nuclear transport factor 2, eukaryote, IPR012677=Nucleotide-binding alpha-beta plait domain" CG9412 16-Dec-15 2015_12 "ENSDARG00000014790(g3bp2),ENSDARG00000011704(zgc:56304),ENSDARG00000017741(g3bp1)" WBGene00010677(K08F4.2) "ENSXETG00000010712(TGas030k06.1),ENSXETG00000000334(TNeu091i16.1)" "ENSMUSG00000018583(G3bp1),ENSMUSG00000029405(G3bp2)" " embryonic stage--pupal stage , adult stage | female " " embryonic stage -- adult stage , larval stage | third instar " " eye disc

, photoreceptor cell | precursor

" "lethal,recessive,viable,fertile,visible,planar polarity defective,wild-type,size defective,somatic clone,sterile,lethal - all die before end of pupal stage,some die during pupal stage" "eye,ommatidium,eye photoreceptor cell,eye disc,somatic clone,supernumerary,wing,ommatidial precursor cluster" DRSC22997 K 2.35833026 0.798363735 FBgn0000173 ben bendless http://flybase.net/reports/FBgn0000173.html FBgn0066817 protein_coding_gene "0031625=ubiquitin protein ligase binding, 0004842=ubiquitin-protein transferase activity, 0061630=ubiquitin protein ligase activity, 0031624=ubiquitin conjugating enzyme binding" "0060074=synapse maturation, 0072347=response to anesthetic, 0000209=protein polyubiquitination, 0007409=axonogenesis, 0010942=positive regulation of cell death, 0045977=positive regulation of mitotic cell cycle, embryonic, 0007625=grooming behavior, 0016567=protein ubiquitination, 0006979=response to oxidative stress, 0051124=synaptic growth at neuromuscular junction, 0007629=flight behavior, 1902916=positive regulation of protein polyubiquitination, 0007630=jump response, 0046330=positive regulation of JNK cascade, 0008594=photoreceptor cell morphogenesis, 0007412=axon target recognition" "0048471=perinuclear region of cytoplasm, 0005634=nucleus, 0035370=UBC13-UEV1A complex" "Ubc13, nonjumper-262, ubc13, UBC13, BEN, CG18319, Ben, nj-262, Bend, UbcD3, Bendless, anon-WO03040301.242" "IPR000608=Ubiquitin-conjugating enzyme E2, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR023313=Ubiquitin-conjugating enzyme, active site" CG18319 16-Dec-15 2015_12 ENSDARG00000008748(ube2n) YDR092W(UBC13) WBGene00006708(ubc-13) ENSXETG00000011697(ube2n) ENSMUSG00000074781(Ube2n) "ENSG00000177889(UBE2N),ENSG00000102069(UBE2NL)" " larval stage | third instar , pupal stage && adult stage , embryonic stage | >= stage 11 , embryonic stage | stage >=11 " " larval muscle system

, retina

, ventral nerve cord

, supraesophageal ganglion

, embryonic/larval digestive system

, imaginal disc

, peripheral nervous system

, subesophageal ganglion

, thoracico-abdominal ganglion

, embryonic/larval salivary gland

, embryonic central nervous system | presumptive

, proventriculus

" "locomotor behavior defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wild-type,jumping defective,behavior defective,neuroanatomy defective,lethal,partially,uncoordinated,grooming behavior defective,neurophysiology defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,partially lethal - majority die,some die during pharate adult stage,chemical sensitive" "photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,optic cartridge,giant fiber neuron,mesothoracic extracoxal depressor muscle 66,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere R7,retina,lamina anlage,medulla anlage,rhabdomere R8,photoreceptor cell R1,photoreceptor cell R2,tergotrochanteral muscle motor neuron,gap junction,synapse,centrosome | non-rescuable maternal effect,spindle | non-rescuable maternal effect,centrosome | non-rescuable maternal effectKA10),spindle | non-rescuable maternal effectKA10),chaeta,supernumerary,mesothoracic tergum" DRSC20310 I 2.293546016 -0.365465392 0.387234022 0.176879289 0.435776254 -0.182533417 FBgn0263111 cac cacophony http://flybase.net/reports/FBgn0263111.html "FBgn0005563, FBgn0000249, FBgn0001518, FBgn0001754, FBgn0002923, FBgn0002958, FBgn0005430, FBgn0020500, FBgn0025106, FBgn0040856" protein_coding_gene "0008331=high voltage-gated calcium channel activity, 0005245=voltage-gated calcium channel activity, 0005509=calcium ion binding, 0008332=low voltage-gated calcium channel activity" "0006887=exocytosis, 0016057=regulation of membrane potential in photoreceptor cell, 0070050=neuron cellular homeostasis, 0007602=phototransduction, 0046928=regulation of neurotransmitter secretion, 0002027=regulation of heart rate, 0006914=autophagy, 0007632=visual behavior, 0006816=calcium ion transport, 0070588=calcium ion transmembrane transport, 0007268=synaptic transmission, 0007269=neurotransmitter secretion, 0045433=male courtship behavior, veined wing generated song production, 0042045=epithelial fluid transport, 0010524=positive regulation of calcium ion transport into cytosol, 0000046=autophagic vacuole fusion, 0045887=positive regulation of synaptic growth at neuromuscular junction, 0007619=courtship behavior, 0050908=detection of light stimulus involved in visual perception, 0008344=adult locomotory behavior" "0048786=presynaptic active zone, 0016324=apical plasma membrane, 0016323=basolateral plasma membrane, 0005891=voltage-gated calcium channel complex" "opm47, CG1522, Cac, Cacaphony, EE171, no-on-transient B, l(1)11Aa, Ca[[V]]2.1, 13, nightblind, Dmca1A, nonB, L13, cac1, unnamed, opm18, H47, Calcium channel alpha1 subunit, type A, ldg, cacaphony, P18, lamina-degeneration, lethal(1)11Aa, Cacophony, nightblind A, Ca-alpha1A, CAC, night blind A, CG15928, nbA, CG43368, l(1)13, l(1)L13, H18, Dmcalpha1A, cacophany, alpha1A" "IPR002077=Voltage-dependent calcium channel, alpha-1 subunit, IPR002048=EF-hand domain, IPR027359=Voltage-dependent channel, four helix bundle domain, IPR014873=Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, IPR005821=Ion transport domain, IPR005446=Voltage-dependent calcium channel, L-type, alpha-1 subunit" CG43368 16-Dec-15 2015_12 "ENSDARG00000037905(cacna1aa),ENSDARG00000006923(cacna1ab),ENSDARG00000021735(cacna1ba),ENSDARG00000062346" YGR217W(CCH1) WBGene00006742(unc-2) ENSXETG00000012458(CACNA1E) "ENSMUSG00000034656(Cacna1a),ENSMUSG00000004113(Cacna1b),ENSMUSG00000004110(Cacna1e)" "ENSG00000141837(CACNA1A),ENSG00000148408(CACNA1B),ENSG00000198216(CACNA1E)" " pupal stage , larval stage , embryonic stage " embryonic central nervous system

FBgn0261612 CngA Cyclic nucleotide-gated ion channel subunit A http://flybase.net/reports/FBgn0261612.html "FBgn0014462, FBgn0034100" protein_coding_gene 0005221=intracellular cyclic nucleotide activated cation channel activity "0001666=response to hypoxia, 0019934=cGMP-mediated signaling, 0055085=transmembrane transport, 0006812=cation transport" 0017071=intracellular cyclic nucleotide activated cation channel complex "Cng, DmCNGC, CNG, dCNCalpha, Cyclic-nucleotide-gated ion channel protein, dmCNGA, cng, CG7779, CNG channel alpha subunit, CG42701, CNG-channel, CG15709" "IPR018490=Cyclic nucleotide-binding-like, IPR000595=Cyclic nucleotide-binding domain, IPR005821=Ion transport domain, IPR014710=RmlC-like jelly roll fold, IPR018488=Cyclic nucleotide-binding, conserved site" CG42701 16-Dec-15 2015_12 "ENSDARG00000060287(cnga5),ENSDARG00000031398,ENSDARG00000070726,ENSDARG00000012297,ENSDARG00000012125,ENSDARG00000029898(LOC100001558)" WBGene00006526(tax-4) "ENSXETG00000024338(CNGA3),ENSXETG00000009833(CNGA1)" "ENSMUSG00000026114(Cnga3),ENSMUSG00000005864(Cnga2),ENSMUSG00000067220(Cnga1)" "ENSG00000144191(CNGA3),ENSG00000198515(CNGA1),ENSG00000183862(CNGA2)" DRSC06580 E -0.717067805 -1.47957896 0.799212727 -2.828000572 -1.34443183 -0.008155526 FBgn0265139 Gr2a Gustatory receptor 2a http://flybase.net/reports/FBgn0265139.html "FBgn0027796, FBgn0029579, FBgn0041251" protein_coding_gene "0008527=taste receptor activity, 0004930=G-protein coupled receptor activity" 0050909=sensory perception of taste 0016021=integral component of membrane "EG:BACN32G11.1, Gustatory receptor 1F.1, CG18531, Gr2B1, GR2B1, Gr1F1, GR1F.1, Gustatory receptor 2B1, GR2a" IPR013604=7TM chemoreceptor CG18531 16-Dec-15 2015_12 WBGene00001803(lite-1) DRSC18603 I 2.003528084 0.78280471 -0.012384935 0.199504004 -0.305902663 -0.220138543 FBgn0264542 CG43921 http://flybase.net/reports/FBgn0264542.html "FBgn0030399, FBgn0259109, FBgn0030397, FBgn0052653, FBgn0046808" protein_coding_gene 0090175=regulation of establishment of planar polarity "CG11146, CG32653, lincRNA.981, BcDNA:GH02424, CG42251, CG15729" "IPR011011=Zinc finger, FYVE/PHD-type, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR000980=SH2 domain, IPR019786=Zinc finger, PHD-type, conserved site" CG43921 16-Dec-15 2015_12 DRSC19386 I 1.398505464 2.419797462 -0.519811268 0.180595291 -0.264638157 0.351990782 FBgn0037147 CG7140 http://flybase.net/reports/FBgn0037147.html protein_coding_gene "0050661=NADP binding, 0004345=glucose-6-phosphate dehydrogenase activity" "0006006=glucose metabolic process, 0055114=oxidation-reduction process" "IPR001282=Glucose-6-phosphate dehydrogenase, IPR016040=NAD(P)-binding domain, IPR022674=Glucose-6-phosphate dehydrogenase, NAD-binding, IPR022675=Glucose-6-phosphate dehydrogenase, C-terminal" CG7140 16-Dec-15 2015_12 ENSXETG00000012078(H6PD) viable DRSC11799 IK 1.531538202 0.41334096 0.720769912 0.154602791 5.091044796 0.867216785 FBgn0260798 Gprk1 G protein-coupled receptor kinase 1 http://flybase.net/reports/FBgn0260798.html "FBan0040129, FBgn0004833, FBgn0058129, FBgn0023488" protein_coding_gene "0004703=G-protein coupled receptor kinase activity, 0004674=protein serine/threonine kinase activity, 0035091=phosphatidylinositol binding, 0001664=G-protein coupled receptor binding, 0050254=rhodopsin kinase activity, 0005524=ATP binding" "0016060=metarhodopsin inactivation, 0006468=protein phosphorylation, 0007474=imaginal disc-derived wing vein specification, 0008277=regulation of G-protein coupled receptor protein signaling pathway, 0038032=termination of G-protein coupled receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0007165=signal transduction, 0007603=phototransduction, visible light" "0005737=cytoplasm, 0005886=plasma membrane" "gprk1, Rok, CT4320, RK, Gprk-1, rhodopsin kinase, CG40129, GPRK1" "IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR001849=Pleckstrin homology domain, IPR000961=AGC-kinase, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000239=GPCR kinase, IPR017441=Protein kinase, ATP binding site, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR016137=RGS domain" CG40129 16-Dec-15 2015_12 ENSDARG00000013007(adrbk2) WBGene00001709(grk-2) "ENSMUSG00000024858(Adrbk1),ENSMUSG00000042249(Adrbk2)" "ENSG00000173020(ADRBK1),ENSG00000100077(ADRBK2)" " embryonic stage -- adult stage , adult stage " "

ubiquitous , adult head

, retina

" DRSC20916 E -1.499315262 0.218449214 2.829835308 0.147172947 0.277244131 -0.343837774 FBgn0038829 CG17271 http://flybase.net/reports/FBgn0038829.html protein_coding_gene 0005509=calcium ion binding 0032504=multicellular organism reproduction 0005615=extracellular space Dm_3R:88623 "IPR018247=EF-Hand 1, calcium-binding site, IPR011992=EF-hand domain pair, IPR002048=EF-hand domain" CG17271 16-Dec-15 2015_12 WBGene00010075(F55A11.1) ENSXETG00000001218(CGREF1) DRSC22982 K 1.852299824 -0.290755036 FBgn0014163 fax failed axon connections http://flybase.net/reports/FBgn0014163.html "FBgn0025997, FBgn0046364, FBgn0046365, FBgn0046366, FBgn0046367, FBgn0046368, FBgn0046369, FBgn0046370" protein_coding_gene "0022008=neurogenesis, 0007409=axonogenesis" "0005886=plasma membrane, 0005737=cytoplasm" "anon-WO0172774.63, clone 1.34, anon-WO0172774.68, fac, anon-WO0172774.66, anon-WO0172774.67, Fax, anon-EST:Liang-1.34, anon-WO0172774.65, Failed Axonal Connections, anon-WO0172774.69, anon-WO0172774.62, CG4609" "IPR026928=Failed axon connections, IPR004045=Glutathione S-transferase, N-terminal, IPR012336=Thioredoxin-like fold, IPR010987=Glutathione S-transferase, C-terminal-like, IPR004046=Glutathione S-transferase, C-terminal" CG4609 16-Dec-15 2015_12 WBGene00013266(Y57A10A.26) ENSMUSG00000028246 ENSG00000146267(C6orf168) embryonic stage " central nervous system

, embryonic peripheral nervous system

, visceral mesoderm

, ectoderm

" pupal stage "lethal,viable,fertile,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" DRSC11345 E -0.7142763 -0.126032227 2.983554487 -1.267297315 -1.444336234 -0.124981293 FBgn0030358 CG10362 http://flybase.net/reports/FBgn0030358.html protein_coding_gene 0019992=diacylglycerol binding 0035556=intracellular signal transduction "IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR001478=PDZ domain" CG10362 16-Dec-15 2015_12 WBGene00008274(C53B4.4) ENSMUSG00000074746(Pdzd8) ENSG00000165650(PDZD8) viable DRSC19355 I 1.014027316 1.766324589 1.072909367 1.254088485 -1.031452762 -1.14521692 FBgn0013762 Cdk5 Cyclin-dependent kinase 5 http://flybase.net/reports/FBgn0013762.html protein_coding_gene "0005524=ATP binding, 0030332=cyclin binding, 0004693=cyclin-dependent protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity" "0035011=melanotic encapsulation of foreign target, 0008582=regulation of synaptic growth at neuromuscular junction, 0070059=intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, 0000278=mitotic cell cycle, 0051642=centrosome localization, 0007409=axonogenesis, 0008045=motor neuron axon guidance, 0007269=neurotransmitter secretion, 0008340=determination of adult lifespan, 0006468=protein phosphorylation, 0007629=flight behavior, 0008344=adult locomotory behavior" 0016533=cyclin-dependent protein kinase 5 holoenzyme complex "CDK5, cyclin-dependent kinase 5, DmCdk5, cdk5, CG8203" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG8203 16-Dec-15 2015_12 ENSDARG00000056683(cdk5) WBGene00000407(cdk-5) ENSMUSG00000028969(Cdk5) ENSG00000164885(CDK5) " embryonic stage -- adult stage , embryonic stage , embryonic stage | early " " embryonic central nervous system

,

ubiquitous , embryonic nervous system

" embryonic stage "neuroanatomy defective,short lived,viable" "presumptive embryonic/larval nervous system,motor neuron | embryonic stage,centrosomeneur-P72,external sensory organ precursor cell I" DRSC07359 K -0.12850455 0.8502728 -0.457304959 1.248809064 -1.570280512 0.36863823 FBgn0028394 CG17834 http://flybase.net/reports/FBgn0028394.html FBgn0063101 protein_coding_gene "anon-290a, anon-29Da, BcDNA:LP07538, unnamed" CG17834 16-Dec-15 2015_12 viable DRSC26694 K -0.609900066 0.400672533 -0.110439607 -0.347384476 2.40024301 -0.110756412 FBgn0260972 alc alicorn http://flybase.net/reports/FBgn0260972.html "FBgn0033383, FBgn0015476" protein_coding_gene "0070050=neuron cellular homeostasis, 0006974=cellular response to DNA damage stimulus, 0035090=maintenance of apical/basal cell polarity" "FBgn0033383, AMPKbeta, 8057, lethal (2) 45Ad, betaAMPK, beta subunit of the SNF1/AMP-activated protein kinase, CG8057, l(2)45Ad, beta homologue, alicorn" "IPR014756=Immunoglobulin E-set, IPR006828=Association with the SNF1 complex (ASC) domain" CG8057 16-Dec-15 2015_12 "ENSDARG00000046143(prkab1b),ENSDARG00000044183(prkab1a)" "YGL208W(SIP2),YER027C(GAL83)" "WBGene00010115(aakb-1),WBGene00012928(aakb-2)" "ENSXETG00000026945(PRKAB1),ENSXETG00000010190(PRKAB2)" "ENSMUSG00000029513(Prkab1),ENSMUSG00000038205(Prkab2)" "ENSG00000111725(PRKAB1),ENSG00000131791(PRKAB2)" DRSC23316 K 0.292159797 -0.194127059 0.383416781 0.224513617 -1.548638228 0.259849654 FBgn0032493 Mabi Mabiki http://flybase.net/reports/FBgn0032493.html protein_coding_gene 0043065=positive regulation of apoptotic process "DM2, CG15479" CG15479 16-Dec-15 2015_12 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02489 K -0.343061898 0.110131053 0.514082962 0.736899366 2.25434361 -0.43078193 FBgn0050481 mRpL53 mitochondrial ribosomal protein L53 http://flybase.net/reports/FBgn0050481.html "FBgn0047273, FBgn0064127, FBtr0089466, FBpp0088473, FBtr0089467, FBpp0088474, FBtr0089468, FBpp0088475, FBtr0089469, FBpp0088476" protein_coding_gene 0003735=structural constituent of ribosome "0035167=larval lymph gland hemopoiesis, 0032543=mitochondrial translation" 0005762=mitochondrial large ribosomal subunit "CG30481, CG33184, BcDNA:GM05817" "IPR019716=Ribosomal protein L53, mitochondrial" CG30481 16-Dec-15 2015_12 ENSDARG00000008920 WBGene00008459(E02H1.8) ENSXETG00000027254(TNeu059d23.1) DRSC05461 E -0.725184896 -0.022961527 -1.684957584 0.207115676 0.085532898 -0.201633316 FBgn0028904 CG16879 http://flybase.net/reports/FBgn0028904.html protein_coding_gene "BG:DS01759.1, DS01759.1" CG16879 16-Dec-15 2015_12 viable DRSC01918 E -0.278866748 0.541183181 1.503980853 0.209125877 -0.207426368 0.42874932 FBgn0039877 CG2118 http://flybase.net/reports/FBgn0039877.html protein_coding_gene "0005524=ATP binding, 0046872=metal ion binding, 0004075=biotin carboxylase activity, 0004485=methylcrotonoyl-CoA carboxylase activity" 0006551=leucine metabolic process 0005759=mitochondrial matrix "mcc, MCC, 3-methyl-crotonyl-CoA carboxylase, Q9V9T5_DROME" "IPR000089=Biotin/lipoyl attachment, IPR001882=Biotin-binding site, IPR005481=Biotin carboxylase-like, N-terminal domain, IPR005482=Biotin carboxylase, C-terminal, IPR011054=Rudiment single hybrid motif, IPR005479=Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR016185=Pre-ATP-grasp domain, IPR011053=Single hybrid motif, IPR013815=ATP-grasp fold, subdomain 1, IPR011761=ATP-grasp fold, IPR013816=ATP-grasp fold, subdomain 2, IPR011764=Biotin carboxylation domain" CG2118 16-Dec-15 2015_12 ENSDARG00000054046(LOC792190) "YBR208C(DUR1,2)" WBGene00009319(F32B6.2) ENSXETG00000016826(mccc1) ENSMUSG00000027709(Mccc1) ENSG00000078070(MCCC1) "heat stress response defective,viable,fertile" DRSC27491 K 0.120019048 0.068028642 -0.091474112 0.829743229 0.492344492 -2.041524452 FBgn0019650 toy twin of eyeless http://flybase.net/reports/FBgn0019650.html FBgn0004523 protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0008056=ocellus development, 0010628=positive regulation of gene expression, 0048749=compound eye development, 0006355=regulation of transcription, DNA-templated, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0048854=brain morphogenesis, 0016319=mushroom body development, 0035214=eye-antennal disc development, 0006357=regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "l(4)8, Pax-6, l(4)102CDg, twin-of-eyeless, Twin of Eyeless, CG11186, lethal(4)102CDg, Toy, twin of eyeless" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001523=Paired domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR001356=Homeobox domain" CG11186 16-Dec-15 2015_12 "ENSDARG00000045936(pax6b),ENSDARG00000045045(pax6a)" ENSMUSG00000027168(Pax6) ENSG00000007372(PAX6) " embryonic stage | stage 9-11 , embryonic stage -- adult stage , larval stage--adult stage " " protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic antennal segment | restricted

" embryonic stage | stage 9-11 " procephalic neurogenic region && embryonic antennal segment | restricted

, procephalic neurogenic region && embryonic ocular segment | restricted

, protocerebral neuroblast | subset

, deuterocerebral neuroblast | subset

" "wild-type,lethal,recessive,partially,heat sensitive,neuroanatomy defective,partially lethal - majority die,increased cell death,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage,viable" "head,eye-antennal disc,embryonic brain,commissure,embryonic/larval brain,adult head,ocellus,adult mushroom body,eye disc,eye,ectopic,leg & eye | ectopicdpp.blk1,wing & eye | ectopicdpp.blk1,leg,wing,antenna,heat sensitive,vertical lobe of adult mushroom body" DRSC17222 I -0.98393883 -1.978601124 0.596112083 -0.7851539 0.52323579 -0.080911847 FBgn0004880 scrt scratch http://flybase.net/reports/FBgn0004880.html "FBgn0064785, FBgn0066002" protein_coding_gene "0046872=metal ion binding, 0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048813=dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "anon-WO02059370.57, clone 1.31, anon-EST:Liang-1.31, CG1130, Scrt, Scratch, anon-EST:Liang-1.67, clone 1.67, BcDNA:RH71479, lincRNA.S4061" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR029794=Transcriptional repressor SCRATCH 1/2, IPR007087=Zinc finger, C2H2" CG1130 16-Dec-15 2015_12 WBGene00022592(ZC328.2) " embryonic stage , embryonic stage | 5.5 hr , embryonic stage | 5-5.5 hr , embryonic stage | >6.5 hr , embryonic stage | 4-12 hr , larval stage | third instar , pupal stage " " ganglion mother cell

, stage 1 neuroblast | row 1..3

, ectoderm | restricted

, stage 1 neuroblast

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, sensory mother cell

, dorsal mesothoracic disc | restricted

, wing | restricted

" "visible,recessive,uncoordinated,behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "neuron,photoreceptor cell,macrochaeta,microchaeta,posterior crossvein,anterior crossvein,eye,wing,eye photoreceptor cell,pigment cell" FBgn0003053 peb pebbled http://flybase.net/reports/FBgn0003053.html "FBgn0001209, FBgn0019888" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003676=nucleic acid binding, 0046872=metal ion binding" "0035160=maintenance of epithelial integrity, open tracheal system, 0008293=torso signaling pathway, 0046665=amnioserosa maintenance, 0007390=germ-band shortening, 0042067=establishment of ommatidial planar polarity, 0007424=open tracheal system development, 0048749=compound eye development, 0046329=negative regulation of JNK cascade, 0008594=photoreceptor cell morphogenesis, 0007362=terminal region determination, 0007393=dorsal closure, leading edge cell fate determination, 0035152=regulation of tube architecture, open tracheal system, 0048190=wing disc dorsal/ventral pattern formation, 0016318=ommatidial rotation, 0007398=ectoderm development, 0007391=dorsal closure, 0006355=regulation of transcription, DNA-templated, 0008258=head involution" 0005634=nucleus "unnamed, Hin, EP55, Pebbled, Peb, PEB, hindsight, HNT, EG:66A1.1, Hnt, hnt, Hind, Hindsight, hnd, CG12212, anon-4Cg" "IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2" CG12212 16-Dec-15 2015_12 "ENSDARG00000042652(si:ch211-279l9.6),ENSDARG00000063701(si:ch211-266d19.3)" ENSXETG00000015435(RREB1) ENSMUSG00000039087(Rreb1) ENSG00000124782(RREB1) embryonic stage | stage >=5 amnioserosa | presumptive

" embryonic stage | >=stage 11 , embryonic stage | stage >=11 , embryonic stage | stage >=6 , embryonic stage | stage 12 , embryonic stage | stage >=8 " " embryonic/larval tracheal system

, embryonic peripheral nervous system

, amnioserosa | presumptive

, CNS glial cell

, anterior midgut proper primordium

, PNS glial cell

" "partially lethal - majority die,visible,lethal,lethal - all die before end of embryonic stage,partially,recessive,some die during embryonic stage,wild-type,somatic clone,viable,heat sensitive,planar polarity defective" "eye,embryonic/first instar larval cuticle,dorsal,extended germ band embryo,ommatidial precursor cluster,somatic clone,amnioserosa,dorsal closure embryo,cephalopharyngeal skeleton,five-cell ommatidial precursor cluster,eye photoreceptor cell,embryonic/larval dorsal trunk,embryonic/larval tracheal system,posterior,taenidium,taenidial fold,germ band,embryonic head,dorsal bridge,vertical bridge,cuticle,filzkorper,heat sensitive,ommatidium,interommatidial bristle,rhabdomere,salivary gland,anterior" FBgn0259984 kuz kuzbanian http://flybase.net/reports/FBgn0259984.html "FBgn0086292, FBgn0015954, FBgn0001958, FBgn0010555, FBgn0069197" protein_coding_gene "0008270=zinc ion binding, 0004222=metalloendopeptidase activity" "0006509=membrane protein ectodomain proteolysis, 0007411=axon guidance, 0035051=cardiocyte differentiation, 0007298=border follicle cell migration, 0007220=Notch receptor processing, 0008347=glial cell migration, 0007519=skeletal muscle tissue development, 0003007=heart morphogenesis, 0007219=Notch signaling pathway, 0007417=central nervous system development, 0060537=muscle tissue development, 0048542=lymph gland development, 0030516=regulation of axon extension, 0048477=oogenesis, 0061320=pericardial nephrocyte differentiation, 0035386=regulation of Roundabout signaling pathway, 0007400=neuroblast fate determination, 0006909=phagocytosis" "0016021=integral component of membrane, 0098595=perivitelline space" "Kuzbanian, l34Da, lethal (2) c00136, CG7147, CT22079, l(2)34Da, l(2)k01403, GS11410, l(2)c00136, BG:DS07660.3, l(2)03782, soy nut, unnamed, 34Da, kuzbaninan, ADAM10, 11410, Kuz, br38, l(2)br38" "IPR001590=Peptidase M12B, ADAM/reprolysin, IPR002870=Peptidase M12B, propeptide, IPR001762=Disintegrin domain, IPR024079=Metallopeptidase, catalytic domain" CG7147 16-Dec-15 2015_12 "ENSDARG00000053468(adam10a),ENSDARG00000015502" WBGene00006324(sup-17) ENSXETG00000010850(ADAM10) ENSMUSG00000054693(Adam10) ENSG00000137845(ADAM10) " larval stage | third instar , embryonic stage | late , embryonic stage " " ommatidial precursor cluster

, embryonic central nervous system

, epidermis

, ventral nerve cord

, morphogenetic furrow

, imaginal disc | ubiquitous

,

ubiquitous , eye-antennal disc

" FBgn0013272 Gp150 Gp150 http://flybase.net/reports/FBgn0013272.html "FBgn0022992, FBgn0025238, FBgn0027193" protein_coding_gene "0002121=inter-male aggressive behavior, 0007185=transmembrane receptor protein tyrosine phosphatase signaling pathway, 0048749=compound eye development" 0005886=plasma membrane "l(2)52A, anon-EST:fe2A1, p150, anon-fast-evolving-2A1, glycoprotein 150, GP150, gp150, CG5820, CT18251, unnamed" "IPR001611=Leucine-rich repeat, IPR003591=Leucine-rich repeat, typical subtype" CG5820 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage 3-12 , embryonic stage | stage 10-12 " "

ubiquitous ,

segmentally repeated , ventral midline

" larval stage eye disc

"lethal,recessive,partially lethal - majority die,female sterile,visible,male semi-sterile,lethal - all die before end of pupal stage,some die during pupal stage,body color defective,behavior defective" "ommatidium,wing margin bristle,ectopic,wing vein L3,eye,eye photoreceptor cell,somatic clone,photoreceptor cell R8,cell autonomous,anterior scutellar bristle,photoreceptor cell R1,photoreceptor cell R6,macrochaeta,ocellar bristle,mesothoracic tergum & microchaeta,wing margin,mesothoracic tergum,chaeta,supernumerary,trichogen cell" FBgn0021742 C901 C901 http://flybase.net/reports/FBgn0021742.html FBgn0014895 protein_coding_gene 0007154=cell communication 0016020=membrane "CT4052, 10, CG1567, anon-10Ab, c901, cDNA 901" "IPR000742=EGF-like domain, IPR013032=EGF-like, conserved site, IPR001774=Delta/Serrate/lag-2 (DSL) protein" CG1567 16-Dec-15 2015_12 "ENSXETG00000014111(NPNT),ENSXETG00000013340(EGFL6)" "ENSMUSG00000012017(Scarf2),ENSMUSG00000038188(Scarf1)" "ENSG00000171462(DLK2),ENSG00000185559(DLK1)" " larval stage | second instar , larval stage | first instar , embryonic stage | 9-15hr , pupal stage , embryonic stage | 8-12hr " "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0016762 angel angel http://flybase.net/reports/FBgn0016762.html protein_coding_gene "CG12273, Angel" IPR005135=Endonuclease/exonuclease/phosphatase CG12273 16-Dec-15 2015_12 WBGene00020955(W02G9.5) ENSXETG00000014357(ANGEL2) "ENSMUSG00000021257(Angel1),ENSMUSG00000026634(Angel2)" "ENSG00000013523(ANGEL1),ENSG00000174606(ANGEL2)" " embryonic stage , embryonic stage -- adult stage "

ubiquitous viable FBgn0261714 Cpn Calphotin http://flybase.net/reports/FBgn0261714.html "FBgn0010218, FBgn0004451, FBgn0002637" protein_coding_gene 0005509=calcium ion binding "0051208=sequestering of calcium ion, 0042052=rhabdomere development" "0005791=rough endoplasmic reticulum, 0030424=axon, 0044297=cell body, 0005739=mitochondrion, 0016028=rhabdomere, 0005634=nucleus, 0005737=cytoplasm" "CG4795, Monoclonal antibody 77H5, 77H5, cap, Mab77H5, Ag 72H5, calphotin, calcium-binding protein, Ag72H5, cpn" CG4795 16-Dec-15 2015_12 adult stage " head

, ocellus

, photoreceptor cell R1--8

, adult head

{ - cli* } " " adult stage , larval stage,adult stage , larval stage && adult stage , larval stage | third instar " " ocellus

, photoreceptor cell R1--8

, optic lobe

, photoreceptor cell

{ 0 gl* } , eye-antennal disc

" FBgn0005603 yemG3.4 yema gene 3.4 http://flybase.net/reports/FBgn0005603.html FBgn0004042 gene "yG3.4, yT3.4, unnamed" 16-Dec-15 2015_12 " embryonic stage | stage 1-5 , adult stage && oogenesis stage , embryonic stage | pre-blastoderm " " organism

, ovary

" FBgn0060296 pain painless http://flybase.net/reports/FBgn0060296.html "FBgn0035080, FBgn0043363" protein_coding_gene "0005262=calcium channel activity, 0005216=ion channel activity, 0005227=calcium activated cation channel activity" "0070588=calcium ion transmembrane transport, 0006816=calcium ion transport, 0007631=feeding behavior, 0050974=detection of mechanical stimulus involved in sensory perception, 0007620=copulation, 0050965=detection of temperature stimulus involved in sensory perception of pain, 0048266=behavioral response to pain, 0009612=response to mechanical stimulus, 0048060=negative gravitaxis, 0008049=male courtship behavior, 0007638=mechanosensory behavior, 0045924=regulation of female receptivity, 0043052=thermotaxis, 0009408=response to heat, 0019233=sensory perception of pain, 0050960=detection of temperature stimulus involved in thermoception, 0008016=regulation of heart contraction, 0042048=olfactory behavior" "0034704=calcium channel complex, 0016021=integral component of membrane" "CG15860, PAINLESS, Pain, Painless, CT31987, EP2251" "IPR005821=Ion transport domain, IPR030288=Transient receptor potential ankyrin 1 channel, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG15860 16-Dec-15 2015_12 " embryonic stage , embryonic stage | stage 17 ," " antenno-maxillary complex

, chordotonal organ

, multidendritic dendrite

, multidendritic neuron

, gonad

, embryonic heart

, central nervous system

restricted " " embryonic stage | stage 17 , larval stage | third instar " " chordotonal organ

, multidendritic dendrite

" "taste perception defective,chemosensitive behavior defective,courtship behavior defective,gravitaxis defective,neurophysiology defective,smell perception defective,sensory perception defective,pain response defective,recessive,heat stress response defective,thermotaxis behavior defective,touch sensitivity defective,lethal,partially,semidominant,visible,wild-type,viable" "Johnston organ neuron,embryonic/larval heart,scutellar bristle,ectopic" DRSC28351 K 1.132512419 -0.125975082 0.528416464 -0.301034969 0.026232244 2.576307954 FBgn0052380 SMSr SMSr http://flybase.net/reports/FBgn0052380.html "FBgn0035774, FBgn0035775" protein_coding_gene "0033188=sphingomyelin synthase activity, 0047493=ceramide cholinephosphotransferase activity" "0060305=regulation of cell diameter, 0046513=ceramide biosynthetic process, 0006686=sphingomyelin biosynthetic process, 2000303=regulation of ceramide biosynthetic process, 0007030=Golgi organization" "0016021=integral component of membrane, 0030176=integral component of endoplasmic reticulum membrane" "dmSMSr, CG32380, dSMSr, CPE synthase, CG8572, CG8576, Css3beta" "IPR013761=Sterile alpha motif/pointed domain, IPR001660=Sterile alpha motif domain, IPR025749=Sphingomyelin synthase-like domain" CG32380 16-Dec-15 2015_12 "ENSDARG00000029621(zgc:154039),ENSDARG00000057053(zgc:91976),ENSDARG00000052520(sgms2),ENSDARG00000036897(zgc:100911)" WBGene00018735(F53B1.2) ENSXETG00000009864(samd8) ENSMUSG00000021770(Samd8) ENSG00000156671(SAMD8) "viable,fertile" DRSC10999 I -0.644999539 -1.963394644 -0.122716862 -0.391140968 -1.256008827 0.842599466 FBgn0003204 ras raspberry http://flybase.net/reports/FBgn0003204.html "FBgn0026670, FBgn0026696, FBgn0028270, FBgn0028295, FBgn0028297, FBgn0028302, FBgn0028318, FBgn0028340, FBgn0028363, FBgn0029044, FBgn0030231, FBgn0030232, FBgn0040205" protein_coding_gene 0003938=IMP dehydrogenase activity "0007411=axon guidance, 0006909=phagocytosis, 0006177=GMP biosynthetic process, 0048477=oogenesis, 0055114=oxidation-reduction process, 0006164=purine nucleotide biosynthetic process" "l(1)G0482, l(1)G0380, l(1)G0351, raspberry/impd, raspberry-lethal, l(1)G0056, l(1)G0002, Ras, l(1)G0238, IMPDH, l(1)9Eb, EP(X)1093, l(1)G0391, ras-l, LD02673, IMPdH, l(1)G0127, inosine monophosphate dehydrogenase, l(1)G0436, l(1)G0388, IMP dehydrogenase, CG11485, raspberry, CG1799, l(1)G0098, lethal (1) G0380, LD06825" "IPR005990=Inosine-5'-monophosphate dehydrogenase, IPR001093=IMP dehydrogenase/GMP reductase, IPR013785=Aldolase-type TIM barrel, IPR015875=IMP dehydrogenase / GMP reductase, conserved site, IPR000644=CBS domain" CG1799 16-Dec-15 2015_12 "ENSDARG00000029524(impdh1b),ENSDARG00000042336(impdh1a),ENSDARG00000006900(impdh2)" "YLR432W(IMD3),YHR216W(IMD2),YML056C(IMD4)" WBGene00020682(T22D1.3) "ENSXETG00000009343(impdh2),ENSXETG00000023047(impdh1)" "ENSMUSG00000003500(Impdh1),ENSMUSG00000062867(Impdh2)" "ENSG00000106348(IMPDH1),ENSG00000178035(IMPDH2)" " spermatogenesis && adult stage , embryonic stage -- adult stage , oogenesis stage && adult stage | female " " testis

, ovary

" "viable,fertile,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,female,partially lethal - majority die,visible,neuroanatomy defective,eye color defective,developmental rate defective,female sterile,partially,heat sensitive" "macrochaeta,embryonic/larval hemocyte | third instar larval stage,photoreceptor cell & axon,pigment cell,ovariole,germline clone,egg,Malpighian tubule,heat sensitive,testis" DRSC27137 IEK 1.79588902 0.12656012 2.024175332 -0.919064105 -1.11927727 -1.53594252 FBgn0031492 CG3542 http://flybase.net/reports/FBgn0031492.html protein_coding_gene 0017058=FH1 domain binding "0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005685=U1 snRNP" prp40 "IPR001202=WW domain, IPR027237=Pre-mRNA-processing protein PRP40, IPR002713=FF domain" CG3542 16-Dec-15 2015_12 ENSDARG00000058467(prpf40a) YKL012W(PRP40) WBGene00014218(ZK1098.1) "ENSXETG00000000580(PRPF40B),ENSXETG00000021713(PRPF40A)" "ENSMUSG00000061136(Prpf40a),ENSMUSG00000023007(Prpf40b)" "ENSG00000196504(PRPF40A),ENSG00000110844(PRPF40B)" "lethal,recessive,viable,visible" "trichogen cell,mesothoracic tergum" DRSC00612 E -0.159520528 -0.6607872 -0.178901226 -1.782933201 -0.729295803 0.075788606 FBgn0000055 Adh Alcohol dehydrogenase http://flybase.net/reports/FBgn0000055.html "FBgn0016704, FBgn0052954" protein_coding_gene "0042803=protein homodimerization activity, 0008774=acetaldehyde dehydrogenase (acetylating) activity, 0004022=alcohol dehydrogenase (NAD) activity" "0006117=acetaldehyde metabolic process, 0006069=ethanol oxidation, 0048149=behavioral response to ethanol, 0006066=alcohol metabolic process, 0046164=alcohol catabolic process, 0006067=ethanol metabolic process" "0005829=cytosol, 0005875=microtubule associated complex, 0005811=lipid particle, 0043234=protein complex" "CG3481, BG:DS01486.8, T16, ADH, dADH, DM-ADH, Adh3, alcoholdehydrogenase, alcohol dehyrdrogenase, Reg-1, adh, Drosophila Rhythmically expressed gene 1, DmADH, CG32954, Dreg-1, alcohol dehydrogenase" "IPR002425=Alcohol dehydrogenase, Drosophila-type, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR016040=NAD(P)-binding domain, IPR020904=Short-chain dehydrogenase/reductase, conserved site, IPR002424=Alcohol dehydrogenase, insect-type" CG3481 16-Dec-15 2015_12 " adult stage , larval stage , larval stage | third instar , adult stage && oogenesis stage , embryonic stage | stage 17 , embryonic stage | early , embryonic stage | stage 14-16 , embryonic stage | stage 16 , embryonic stage | stage 14-15 " " cardial valve

, pharyngeal muscle

, embryonic/larval salivary gland

, gastric caecum

, nurse cell

, imaginal disc

, embryonic/larval midgut

, embryonic/larval fat body

, posterior embryonic/larval midgut

, larval brain

, mid embryonic/larval midgut

, oocyte

, anterior embryonic/larval midgut

, adult fat body

, adult brain

" " adult stage , adult stage && oogenesis stage , larval stage " " Malpighian tubule

, ovary

, cardial valve

, nurse cell

, midgut

, cystocyte

, adult fat body

, oocyte

, embryonic/larval digestive system

, embryonic/larval fat body

, gastric caecum

, male reproductive system

" "chemical sensitive,electrophoretic variant,fast,wild-type,slow,locomotor behavior defective,drug conditional,chemical resistant" FBgn0036288 CG10660 http://flybase.net/reports/FBgn0036288.html protein_coding_gene IPR000008=C2 domain CG10660 16-Dec-15 2015_12 viable DRSC09769 E 0.210534236 -0.811158656 2.675545125 -2.589505753 0.848558629 0.854153372 FBgn0035533 Cip4 Cdc42-interacting protein 4 http://flybase.net/reports/FBgn0035533.html FBgn0040698 protein_coding_gene "0032794=GTPase activating protein binding, 0005515=protein binding, 0008289=lipid binding, 0017048=Rho GTPase binding, 0005543=phospholipid binding" "0030837=negative regulation of actin filament polymerization, 0097320=membrane tubulation, 0051126=negative regulation of actin nucleation, 1903391=regulation of adherens junction organization, 0007498=mesoderm development, 0030708=germarium-derived female germ-line cyst encapsulation, 0008582=regulation of synaptic growth at neuromuscular junction, 0007349=cellularization, 0007009=plasma membrane organization, 0007165=signal transduction, 0035317=imaginal disc-derived wing hair organization, 0034613=cellular protein localization, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0008104=protein localization" "0012506=vesicle membrane, 0030496=midbody, 0005886=plasma membrane, 0032154=cleavage furrow, 0031594=neuromuscular junction" "CG15015, dCIP4, Cdc42-Interacting Protein 4, Cdc42-interacting protein 4, cip4, DCIP4, CG11341, Cip4, dcip4" "IPR001060=FCH domain, IPR031160=F-BAR domain, IPR001452=SH3 domain, IPR011072=HR1 rho-binding repeat" CG15015 16-Dec-15 2015_12 "ENSDARG00000038219,ENSDARG00000036156(LOC558990),ENSDARG00000020131(fnbp1l),ENSDARG00000005679(zgc:101777)" WBGene00017298(toca-1) "ENSXETG00000012848(FNBP1),ENSXETG00000008227(fnbp1l)" "ENSMUSG00000019487(Trip10),ENSMUSG00000075415(Fnbp1),ENSMUSG00000039735(Fnbp1l)" "ENSG00000137942(FNBP1L),ENSG00000187239(FNBP1),ENSG00000125733(TRIP10)" "visible,viable,lethal,fertile,partially lethal - majority die,neuroanatomy defective" "wing hair,supernumerary,wing,NMJ bouton,neuromuscular junction,neuromuscular junctionED4342),neuromuscular junctionC57,bouton" DRSC21740 I 1.174162123 -1.654727835 -0.134553747 1.295642373 0.557609548 -0.067657873 FBgn0010497 dmGlut Dietary and metabolic glutamate transporter http://flybase.net/reports/FBgn0010497.html "FBgn0032396, FBgn0061550" protein_coding_gene "0005316=high-affinity inorganic phosphate:sodium symporter activity, 0015321=sodium-dependent phosphate transmembrane transporter activity, 0005314=high-affinity glutamate transmembrane transporter activity, 0015319=sodium:inorganic phosphate symporter activity" "0051938=L-glutamate import, 0006541=glutamine metabolic process, 0055085=transmembrane transport, 0044341=sodium-dependent phosphate transport, 0007005=mitochondrion organization" "0005886=plasma membrane, 0016021=integral component of membrane" "I(2)01810, dietary and metabolic glutamate transporter, l(2)01810, lethal(2)01810, DMGLUT, CG5304, anon-WO0118547.88, MFS13, lethal (2) 01810" "IPR011701=Major facilitator superfamily, IPR020846=Major facilitator superfamily domain" CG5304 16-Dec-15 2015_12 "YOR378W(),YML116W(ATR1),YMR279C()" "viable,partially lethal - majority die,lethal,recessive" DRSC02835 E -0.454567138 0.249802624 -0.445641978 1.627740877 0.153558934 -0.121219183 FBgn0050491 CG30491 http://flybase.net/reports/FBgn0050491.html "FBgn0033200, FBgn0033201" protein_coding_gene 0016491=oxidoreductase activity 0008152=metabolic process "CG2074, CG17986" "IPR016040=NAD(P)-binding domain, IPR002198=Short-chain dehydrogenase/reductase SDR, IPR002347=Glucose/ribitol dehydrogenase" CG30491 16-Dec-15 2015_12 "ENSDARG00000045277(rdh12l),ENSDARG00000018069(rdh12),ENSDARG00000068474(si:dkey-94e7.2),ENSDARG00000058966(zgc:112332),ENSDARG00000071660,ENSDARG00000008491(LOC407663),ENSDARG00000054797(zgc:153441)" YOR246C() WBGene00000985(dhs-22) ENSXETG00000008385(rdh13) ENSMUSG00000008435(Rdh13) ENSG00000160439(RDH13) viable DRSC21472 IE 1.628864705 0.285729464 2.5400331 1.314574665 1.06633405 -0.185142479 FBgn0052581 CG32581 http://flybase.net/reports/FBgn0052581.html protein_coding_gene "0008270=zinc ion binding, 0004842=ubiquitin-protein transferase activity" 0016567=protein ubiquitination "IPR001841=Zinc finger, RING-type, IPR017907=Zinc finger, RING-type, conserved site, IPR013083=Zinc finger, RING/FYVE/PHD-type" CG32581 16-Dec-15 2015_12 ENSDARG00000032997(zgc:73070) YER116C(SLX8) WBGene00004381(rnf-5) ENSXETG00000004178(RNF185) ENSMUSG00000020448(Rnf185) ENSG00000138942(RNF185) DRSC20136 K 0.673840783 0.280899511 -0.05639009 0.051514521 -0.19695688 1.84177095 FBgn0011676 Nos Nitric oxide synthase http://flybase.net/reports/FBgn0011676.html protein_coding_gene "0010181=FMN binding, 0050661=NADP binding, 0003958=NADPH-hemoprotein reductase activity, 0005506=iron ion binding, 0020037=heme binding, 0004517=nitric-oxide synthase activity, 0050660=flavin adenine dinucleotide binding, 0005516=calmodulin binding" "0002027=regulation of heart rate, 0007444=imaginal disc development, 0008285=negative regulation of cell proliferation, 0046620=regulation of organ growth, 0007399=nervous system development, 0006809=nitric oxide biosynthetic process, 0007416=synapse assembly, 0006952=defense response, 0007263=nitric oxide mediated signal transduction, 0031284=positive regulation of guanylate cyclase activity, 0055114=oxidation-reduction process, 0008156=negative regulation of DNA replication" "0005829=cytosol, 0005777=peroxisome" "NOS, DNOS, dNOS, nNOS, drNOSoxy, Nitric Oxide Synthase, CG6713, nitric oixide synthase, nos, nitric oxide synthase, DNOS1, dNos, NO synthase" "IPR001433=Oxidoreductase FAD/NAD(P)-binding, IPR017927=Ferredoxin reductase-type FAD-binding domain, IPR008254=Flavodoxin/nitric oxide synthase, IPR017938=Riboflavin synthase-like beta-barrel, IPR012144=Nitric-oxide synthase, eukaryote, IPR001709=Flavoprotein pyridine nucleotide cytochrome reductase, IPR004030=Nitric oxide synthase, N-terminal, IPR001094=Flavodoxin, IPR003097=FAD-binding, type 1, IPR029039=Flavoprotein-like, IPR023173=NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3" CG6713 16-Dec-15 2015_12 "ENSDARG00000068910(nos1),ENSDARG00000031976(nos2b)" "ENSXETG00000022354(NOS1),ENSXETG00000011979(NOS3),ENSXETG00000012498()" "ENSMUSG00000029361(Nos1),ENSMUSG00000028978(Nos3),ENSMUSG00000020826(Nos2)" "ENSG00000089250(NOS1),ENSG00000164867(NOS3),ENSG00000007171(NOS2)" adult stage adult head

" larval stage | third instar , larval stage | third instar && P , larval stage | third instar--P , larval stage | third instar && P " " larval brain

, dorsal metathoracic disc

, ventral thoracic disc

, genital disc

, histoblast

" "developmental rate defective,large body,eclosion defective,increased cell size,small body,lethal - all die before end of larval stage,some die during larval stage,chemical resistant,dominant,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "prothoracic gland,embryonic/larval fat body,vesiclephm.PO,eye & cell cycle,secondary pigment cell,tertiary pigment cell,interommatidial bristle,cell cycle,mesothoracic tergum" FBgn0004607 zfh2 Zn finger homeodomain 2 http://flybase.net/reports/FBgn0004607.html protein_coding_gene "0003677=DNA binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0046872=metal ion binding" "0007417=central nervous system development, 0007399=nervous system development, 0006355=regulation of transcription, DNA-templated, 0035220=wing disc development, 0007476=imaginal disc-derived wing morphogenesis" 0005634=nucleus "ZFH-2, Zfh-2, ZFH2, zinc finger homeodomain 2, CG1449, Zinc finger homeodomain-2, Zfh2, zfh-2" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR001356=Homeobox domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR027028=Zinc finger homeobox protein 2" CG1449 16-Dec-15 2015_12 "ENSMUSG00000025255(Zfhx4),ENSMUSG00000038872(Zfhx3)" "ENSG00000091656(ZFHX4),ENSG00000140836(ZFHX3)" " embryonic stage | stage 13-15 , embryonic stage | stage 15 " " embryonic central nervous system

, embryonic/larval hindgut

" " embryonic stage , embryonic stage | stage 15-17 , embryonic stage | stage 13-15 , larval stage , embryonic stage | stage 15 " " embryonic central nervous system | lateral

, EW3 neuron

, embryonic central nervous system

, EW2 neuron

, abdominal 3--6 neuroblast ventro-lateral cluster neuron

, abdominal 3--7 neuroblast dorso-lateral cluster

, embryonic/larval hindgut

, larval central nervous system

" "viable,poor,visible,partially lethal - majority die,some die during pupal stage,lethal,recessive,lethal - all die before end of pupal stage" "wing,proximal,alula,medial costal vein,wing vein L1,wing disc,sclerite,wing hinge,eye,chaeta,ectopic" FBgn0039914 mav maverick http://flybase.net/reports/FBgn0039914.html protein_coding_gene "0008083=growth factor activity, 0005160=transforming growth factor beta receptor binding" "0007179=transforming growth factor beta receptor signaling pathway, 0040007=growth" 0043083=synaptic cleft "Maverick, CG1901, Mav, MAV, TGF-b" "IPR017948=Transforming growth factor beta, conserved site, IPR001111=Transforming growth factor-beta, N-terminal, IPR029034=Cystine-knot cytokine, IPR015615=Transforming growth factor-beta-related, IPR001839=Transforming growth factor-beta, C-terminal" CG1901 16-Dec-15 2015_12 " embryonic stage | stage >=12 , embryonic stage | stage 11,12 , embryonic stage | stage 13 , embryonic stage | stage 7-9 , embryonic stage | stage 11 , adult stage && oogenesis stage | stage >=S10 , embryonic stage | stage 9,10 , embryonic stage -- adult stage , embryonic stage | stage 5-11 " " embryonic esophagus

, embryonic foregut

, visceral mesoderm &&of posterior larval midgut

, endoderm

, visceral mesoderm &&of anterior larval midgut

, anterior midgut proper primordium

, nurse cell

, mesoderm

, embryonic hindgut

, pharynx

, oocyte

, inclusive hindgut primordium

, posterior midgut proper primordium

, organism | ubiquitous

" "neuroanatomy defective,circadian rhythm defective,heat sensitive,partially lethal - majority die,some die during pupal stage" "bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0011236 ken ken and barbie http://flybase.net/reports/FBgn0011236.html "FBgn0010464, FBgn0010525, FBgn0020522, FBgn0024882" protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0007620=copulation, 0007486=imaginal disc-derived female genitalia development, 0006909=phagocytosis, 0045496=male analia development, 0007320=insemination, 0007485=imaginal disc-derived male genitalia development, 0046425=regulation of JAK-STAT cascade, 0045497=female analia development" 0005634=nucleus "unnamed, 3907, 8253, 5029, okina, 2970, l(2)02970, Ken and Barbie, Ken, ok, ken-and-barbie, l(2)05029, ken & barbie, Ken & Barbie, CG5575, KEN, l(2)00628, BCL-6/KEN, P420" "IPR011333=POZ domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG5575 16-Dec-15 2015_12 "ENSDARG00000055493(hic1),ENSDARG00000038298(hic2),ENSDARG00000045660(hic1l)" " embryonic stage | stage 16 , embryonic stage | stage 6-7 , embryonic stage | stage 5-7 , larval stage | third instar , embryonic stage | stage 5 , embryonic stage | stage 15 , embryonic stage -- adult stage , embryonic stage | stage 6-15 , embryonic stage " " dorsal pouch

, cephalic furrow | posterior to

, embryonic/larval foregut

, organism | 20% egg length

, genital disc

, organism | 20% egg length & 70% egg length

, embryonic foregut

, embryonic/larval hindgut

, eye-antennal disc

, organism

, embryonic/larval proventriculus

, tracheal system

, anal pad

, embryonic hindgut

, embryonic/larval posterior spiracle

, organism | 60% egg length

" "visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,dominant,somatic clone" "rhabdomere R7,terminalia,male genital disc,male genitalia,female genitalia,vulva,female analia,arista,female gonopod,penis,clasper,genitalia,antenna,embryonic/larval posterior spiracle,wing margin bristle,somatic clone,tracheal pit" FBgn0264270 Sxl Sex lethal http://flybase.net/reports/FBgn0264270.html "FBgn0003659, FBgn0000823, FBgn0029934, FBgn0053070, FBtr0089822, FBpp0088763, FBtr0089823, FBpp0088764, FBtr0089824, FBpp0088765, FBtr0089825, FBpp0088766, FBtr0089826, FBpp0088767, FBtr0089827, FBpp0088768, FBtr0089828, FBpp0088769, FBtr0089829, FBpp0088770, FBtr0089830, FBpp0088771, FBtr0089831, FBpp0088772, FBgn0029933" protein_coding_gene "0005515=protein binding, 0008083=growth factor activity, 0048027=mRNA 5'-UTR binding, 0000166=nucleotide binding, 0003729=mRNA binding, 0008266=poly(U) RNA binding, 0000900=translation repressor activity, nucleic acid binding, 0008187=poly-pyrimidine tract binding, 0003730=mRNA 3'-UTR binding" "0019099=female germ-line sex determination, 0009994=oocyte differentiation, 0000380=alternative mRNA splicing, via spliceosome, 0007549=dosage compensation, 0017148=negative regulation of translation, 0018993=somatic sex determination, 0019101=female somatic sex determination, 0000398=mRNA splicing, via spliceosome, 0007541=sex determination, primary response to X:A ratio, 0048025=negative regulation of mRNA splicing, via spliceosome, 0007446=imaginal disc growth, 0048477=oogenesis, 0048024=regulation of mRNA splicing, via spliceosome, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007224=smoothened signaling pathway, 0007281=germ cell development, 0007548=sex differentiation, 0007131=reciprocal meiotic recombination, 0030237=female sex determination, 0007530=sex determination" "0005737=cytoplasm, 0043234=protein complex" "melSxl, sex-lethal, fs(1)K1274, Su(da), Sx1, sxl, CG14425/CG18350, SxlPm, DmSxl, CG18350, Sexlethal, Sex-lethal, Female lethal, Sex Lethal, ORF2, Fl, Sex-kethal, CG14425, l(1)6Fa, fs(1)M106, CG33070, SXL, Sxl-1 Sxl-2, SxL, CG43770, Mex156, SxlPe, dSXL, sex lethal" "IPR012677=Nucleotide-binding alpha-beta plait domain, IPR006546=Sex-lethal splicing factor, IPR000504=RNA recognition motif domain, IPR002343=Paraneoplastic encephalomyelitis antigen" CG43770 16-Dec-15 2015_12 "YHR015W(MIP6),YFR023W(PES4)" embryonic stage | embryonic cycle 12-14 " embryonic stage | male , embryonic stage | female " " organism | 50-100% egg length

,

0-55% egg length{ + schb.P } ,

0-100% egg length{ - hhb.P } " DRSC21490 IK -0.732353843 -2.48634286 -0.800901194 1.193402481 3.362931469 2.615196174 FBgn0015295 Shark SH2 ankyrin repeat kinase http://flybase.net/reports/FBgn0015295.html "FBgn0004605, FBgn0010286, FBgn0028603, FBgn0034090" protein_coding_gene "0004713=protein tyrosine kinase activity, 0004715=non-membrane spanning protein tyrosine kinase activity, 0005524=ATP binding" "0007254=JNK cascade, 0006468=protein phosphorylation, 0045199=maintenance of epithelial cell apical/basal polarity, 0043277=apoptotic cell clearance, 0007306=eggshell chorion assembly, 0048812=neuron projection morphogenesis, 0007391=dorsal closure, 0007394=dorsal closure, elongation of leading edge cells, 0046843=dorsal appendage formation" "0005938=cell cortex, 0005737=cytoplasm" "Src homology 2 ankyrin repeat tyrosine kinase, SHARK, l(2)W4, Src homology 2, ankyrin repeat, tyrosine kinase, shark, dtk7, SYK/SHARK, l(2R)W4, Shark, Dtk7, Tyrosine kinase 7, Syk, Src homology2, ankyrin repeat, tyrosine kinase, Tk7, CG18247" "IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR017441=Protein kinase, ATP binding site, IPR000980=SH2 domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR008266=Tyrosine-protein kinase, active site, IPR000719=Protein kinase domain" CG18247 16-Dec-15 2015_12 "ENSDARG00000015752(zap70),ENSDARG00000008186(syk)" "ENSXETG00000009491(ZAP70),ENSXETG00000000807(SYK)" "ENSMUSG00000026117(Zap70),ENSMUSG00000021457(Sykb)" "ENSG00000115085(ZAP70),ENSG00000165025(SYK)" " larval stage | third instar , embryonic stage | 0-12hr " imaginal disc

" embryonic stage , embryonic stage | stage 8-9 , embryonic stage | stage 7-9 , embryonic stage | stage 10-11 , embryonic stage | late , embryonic stage | stage 7 " " gnathal segment

, embryonic/larval esophagus

, frontal head air sac

, stomodeum

, cephalic furrow

, inclusive hindgut primordium

, embryonic/larval pharynx

, invaginating stomatogastric nervous system precursor

, proctodeum

, embryonic/larval foregut

, atrium

, embryonic/larval salivary gland

, embryonic/larval hindgut

, embryonic/larval tracheal system

, ventral midline

" "wild-type,lethal,recessive,germline clone,rescuable maternal effect,viable,cell death defective" "ensheathing neuropil associated glial cell,wing,adult thorax,dorsal,dorsal closure embryo,germline clone,embryonic epidermis,dorsal appendage,somatic clone,chorion | somatic clone,egg chamber,follicle cell" FBgn0025802 Sbf SET domain binding factor http://flybase.net/reports/FBgn0025802.html protein_coding_gene "0008138=protein tyrosine/serine/threonine phosphatase activity, 0036313=phosphatidylinositol 3-kinase catalytic subunit binding, 0019992=diacylglycerol binding, 0030674=protein binding, bridging, 0019902=phosphatase binding, 0004402=histone acetyltransferase activity, 0004725=protein tyrosine phosphatase activity, 0017137=Rab GTPase binding, 0017112=Rab guanyl-nucleotide exchange factor activity, 0003682=chromatin binding, 0042800=histone methyltransferase activity (H3-K4 specific)" "0000278=mitotic cell cycle, 0051568=histone H3-K4 methylation, 0032483=regulation of Rab protein signal transduction, 0016573=histone acetylation, 0030866=cortical actin cytoskeleton organization, 0032456=endocytic recycling, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter" "0005634=nucleus, 0008023=transcription elongation factor complex, 0000123=histone acetyltransferase complex, 0035097=histone methyltransferase complex, 0055037=recycling endosome, 0005700=polytene chromosome, 0005938=cell cortex" "SBF1, dSbf1, SBF, CG6939, sbf, Sbf1, DSbf1" "IPR029021=Protein-tyrosine phosphatase-like, IPR005112=dDENN domain, IPR022096=SBF1/SBF2 domain, IPR001194=DENN domain, IPR002219=Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR010569=Myotubularin-like phosphatase domain, IPR004182=GRAM domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), IPR005113=uDENN domain, IPR030564=Myotubularin family, IPR001849=Pleckstrin homology domain" CG6939 16-Dec-15 2015_12 "ENSDARG00000062968(sbf1),ENSDARG00000059460(cmt4b2)" WBGene00003477(mtm-5) ENSXETG00000023079(SBF1) "ENSMUSG00000038371(Sbf2),ENSMUSG00000036529(Sbf1)" "ENSG00000133812(SBF2),ENSG00000100241(SBF1)" "lethal - all die before end of P-stage,some die during pharate adult stage" macrophage DRSC16852 E 0.388820426 -0.404144164 1.53370148 -0.554951785 -0.558314223 -0.083443024 FBgn0051615 His-ë¬:CR31615 His-ë¬:CR31615 http://flybase.net/reports/FBgn0051615.html pseudogene_attribute "bs28b08.y1, CR31615" CR31615 16-Dec-15 2015_12 DRSC03760 IEK -5.165196415 -6.818911135 -3.264339282 -6.619325611 -2.847291819 -1.664703147 FBgn0040534 CG11985 http://flybase.net/reports/FBgn0040534.html protein_coding_gene "0007052=mitotic spindle organization, 0000398=mRNA splicing, via spliceosome" "0005634=nucleus, 0071011=precatalytic spliceosome, 0005686=U2 snRNP" "IPR017089=Splicing factor 3B, subunit 5, IPR009846=Splicing factor 3B subunit 5/RDS3 complex subunit 10" CG11985 16-Dec-15 2015_12 ENSDARG00000016855(sf3b5) ENSXETG00000021409(SF3B5) ENSMUSG00000078348(Sf3b5) ENSG00000169976(SF3B5) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC14460 IEK -0.31429718 1.81001035 -2.838171322 -0.159559576 -2.090528352 -1.112644158 FBgn0037087 CG7519 http://flybase.net/reports/FBgn0037087.html protein_coding_gene "IPR021148=Putative polysaccharide biosynthesis protein, IPR008476=Uncharacterised protein family UPF0368, metazoa/fungi, IPR023139=Yst0336-like domain" CG7519 16-Dec-15 2015_12 ENSDARG00000057299(zgc:92611) YPL225W() WBGene00013200(Y54E5A.5) ENSXETG00000010543(CXorf26) ENSMUSG00000031226(2610029G23Rik) ENSG00000102390(CXorf26) viable DRSC11834 K 0.53716384 0.165174244 0.694007981 0.311650415 0.145066029 1.797221802 FBgn0046247 CG5938 http://flybase.net/reports/FBgn0046247.html FBgn0039506 protein_coding_gene BEST:LD40095 IPR019383=Golgin subfamily A member 7/ERF4 CG5938 16-Dec-15 2015_12 "ENSDARG00000053166(chic1),ENSDARG00000022690(chic2)" WBGene00044319(tag-266) ENSXETG00000011681(CHIC2) "ENSMUSG00000029229(Chic2),ENSMUSG00000031327(Chic1)" "ENSG00000109220(CHIC2),ENSG00000204116(CHIC1)" "viable,fertile" DRSC24038 EK -0.351441417 -1.194784554 -1.277554129 2.150915356 1.888623144 0.524119735 FBgn0085421 Epac Exchange protein directly activated by cAMP ortholog (H. sapiens) http://flybase.net/reports/FBgn0085421.html "FBgn0033102, FBgn0033103" protein_coding_gene "0017034=Rap guanyl-nucleotide exchange factor activity, 0017132=cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity" 0032487=regulation of Rap protein signal transduction "D-Epac, Epac Guanine Nucleotide Exchange Factor, CG15235, CG3427, Dm_2R:10367, D-EPAC, epac, CG34392, Epac" "IPR000591=DEP domain, IPR000595=Cyclic nucleotide-binding domain, IPR018490=Cyclic nucleotide-binding-like, IPR019804=Ras guanine-nucleotide exchange factor, conserved site, IPR023578=Ras guanine nucleotide exchange factor domain, IPR000159=Ras-associating (RA) domain, IPR000651=Ras-like guanine nucleotide exchange factor, N-terminal, IPR001895=Ras guanine-nucleotide exchange factors catalytic domain, IPR029071=Ubiquitin-related domain, IPR014710=RmlC-like jelly roll fold, IPR011991=Winged helix-turn-helix DNA-binding domain" CG34392 16-Dec-15 2015_12 WBGene00004255(epac-1) ENSXETG00000007521(RAPGEF4) ENSMUSG00000049044(Rapgef4) ENSG00000091428(RAPGEF4) DRSC04997 I 0.308747236 1.588296712 0.621298464 0.690697768 -0.417145711 -0.03701505 FBgn0002044 swm second mitotic wave missing http://flybase.net/reports/FBgn0002044.html "FBgn0019934, FBgn0032794" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0046872=metal ion binding" "0045879=negative regulation of smoothened signaling pathway, 0010628=positive regulation of gene expression, 1900364=negative regulation of mRNA polyadenylation, 0046833=positive regulation of RNA export from nucleus, 0007346=regulation of mitotic cell cycle" 0005634=nucleus "l(2)E1, S(Rux)2B, lethal (2) 37Dh, l(2)37Dh, CG10084, Swm, EC2-10, E1, S(rux)2B" "IPR000504=RNA recognition motif domain, IPR002483=PWI domain, IPR000571=Zinc finger, CCCH-type, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10084 16-Dec-15 2015_12 WBGene00015143(B0336.3) "ENSXETG00000017810(RBM26),ENSXETG00000002322(RBM27)" "ENSMUSG00000024491(Rbm27),ENSMUSG00000022119(Rbm26)" "ENSG00000139746(RBM26),ENSG00000091009(RBM27)" "increased cell size,lethal,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,recessive,mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "wing hair,wing,mesothoracic tergum,wing vein" DRSC21831 E 0.980770036 -0.373857575 1.919337119 0.213522389 0.743617121 1.277714198 FBgn0000581 E(Pc) Enhancer of Polycomb http://flybase.net/reports/FBgn0000581.html FBgn0015874 protein_coding_gene "0016573=histone acetylation, 0070983=dendrite guidance, 0006325=chromatin organization, 0043486=histone exchange" "0000785=chromatin, 0032777=Piccolo NuA4 histone acetyltransferase complex, 0005700=polytene chromosome, 0035267=NuA4 histone acetyltransferase complex, 0005725=intercalary heterochromatin, 0005701=polytene chromosome chromocenter, 0000123=histone acetyltransferase complex, 0005634=nucleus" "Enhancer of polycomb, GH14582, e(pc), anon-48Ac, transcript group III, e(Pc), GH05739, CG7776, l(2)28-28-12, III, E(PC)" "IPR024943=Enhancer of polycomb protein, IPR019542=Enhancer of polycomb-like, N-terminal" CG7776 16-Dec-15 2015_12 "ENSDARG00000025241(epc1),ENSDARG00000060054(zgc:158364),ENSDARG00000007485(epc2)" "ENSXETG00000011660(EPC1),ENSXETG00000024611(epc2)" "ENSMUSG00000024240(Epc1),ENSMUSG00000069495(Epc2)" "ENSG00000120616(EPC1),ENSG00000135999(EPC2)" embryonic stage -- adult stage embryonic stage "

ubiquitous , embryonic central nervous system

" "lethal,recessive,suppressor of variegation,dominant,radiation resistant,neuroanatomy defective,decreased cell number,partially lethal - majority die,visible" "adult antennal lobe projection neuron DL1 adPN,trichogen cell,mesothoracic tergum" DRSC05281 IE 0.761096839 -4.095449321 2.03377399 -5.674167448 0.343384062 -0.366227137 FBgn0264339 CG43795 http://flybase.net/reports/FBgn0264339.html "FBgn0034862, FBgn0085401, FBgn0034864, FBgn0040662, FBgn0034868, FBgn0040664, FBgn0040663" protein_coding_gene 0004965=G-protein coupled GABA receptor activity 0007186=G-protein coupled receptor signaling pathway 0016021=integral component of membrane "CG18678, CG18679, CG13552, CG34372, CG5357, CG13553, CG13556" "IPR000337=GPCR, family 3, IPR002455=GPCR, family 3, gamma-aminobutyric acid receptor, type B, IPR017978=GPCR, family 3, C-terminal" CG43795 16-Dec-15 2015_12 DRSC04497 E 0.575599073 0.938031731 1.722872503 -0.746215603 0.71576584 0.570156932 FBgn0035879 GAPcenA GTPase activating protein and centrosome-associated ortholog (H. sapiens) http://flybase.net/reports/FBgn0035879.html protein_coding_gene 0005096=GTPase activator activity 0043087=regulation of GTPase activity "GapcenA, CG7112, FBgn 35879, FBgn0035879" "IPR022164=Kinesin-like, IPR000195=Rab-GTPase-TBC domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG7112 16-Dec-15 2015_12 WBGene00018075(tbc-11) ENSXETG00000020019(TNeu062j06.1) "ENSMUSG00000035437(Rabgap1),ENSMUSG00000026721(Rabgap1l)" "ENSG00000011454(RABGAP1),ENSG00000152061(LOC100652789)" "viable,fertile" DRSC10771 K 0.160488008 -0.090600095 -0.105011932 -0.275681427 0.296290785 2.126304556 FBgn0037270 CG9769 http://flybase.net/reports/FBgn0037270.html protein_coding_gene "0004843=ubiquitin-specific protease activity, 0003743=translation initiation factor activity" "0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0006413=translational initiation, 0045747=positive regulation of Notch signaling pathway, 0016579=protein deubiquitination" 0005852=eukaryotic translation initiation factor 3 complex "Q9VN50, eIF3-S5, eif3f, eIF3f" "IPR027531=Eukaryotic translation initiation factor 3 subunit F, IPR024969=Rpn11/EIF3F, C-terminal, IPR000555=JAB1/MPN/MOV34 metalloenzyme domain" CG9769 16-Dec-15 2015_12 WBGene00001229(eif-3.F) ENSXETG00000002620(eif3s5) ENSMUSG00000031029(Eif3f) ENSG00000175390(EIF3F) "lethal - all die before end of larval stage,some die during larval stage,lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin bristle" DRSC12328 IEK -2.546542727 -1.382684869 -2.736108172 -2.727027446 -0.536151743 2.223274849 FBgn0036316 CG10960 http://flybase.net/reports/FBgn0036316.html protein_coding_gene 0005355=glucose transmembrane transporter activity "0055085=transmembrane transport, 0046427=positive regulation of JAK-STAT cascade" "0005886=plasma membrane, 0016021=integral component of membrane" CT30701 "IPR005829=Sugar transporter, conserved site, IPR020846=Major facilitator superfamily domain, IPR005828=Major facilitator, sugar transporter-like, IPR003663=Sugar/inositol transporter" CG10960 16-Dec-15 2015_12 "ENSDARG00000020344(slc2a8),ENSDARG00000058731(LOC560602)" "YDL138W(RGT2),YDL194W(SNF3)" "WBGene00010811(hmit-1.3),WBGene00013073(hmit-1.1),WBGene00013074(hmit-1.2)" viable DRSC09807 IE -0.710530261 1.944183123 1.524104828 -0.125012963 0.194891443 -0.192748525 FBgn0028853 CG15263 http://flybase.net/reports/FBgn0028853.html protein_coding_gene BG:DS07851.4 CG15263 16-Dec-15 2015_12 viable DRSC01974 E -0.124149794 0.077289846 0.519762219 1.678885748 0.092135928 0.139354468 FBgn0036391 CG17364 http://flybase.net/reports/FBgn0036391.html protein_coding_gene CG17364 16-Dec-15 2015_12 DRSC10270 E 0.726493289 0.045649938 2.506026959 0.409955976 -0.120580456 -0.705712405 FBgn0039645 CG11898 http://flybase.net/reports/FBgn0039645.html protein_coding_gene "0005524=ATP binding, 0008559=xenobiotic-transporting ATPase activity, 0015238=drug transmembrane transporter activity" 0055085=transmembrane transport 0016021=integral component of membrane Dme_CG11898 "IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR017871=ABC transporter, conserved site, IPR003439=ABC transporter-like, IPR011527=ABC transporter type 1, transmembrane domain, IPR003593=AAA+ ATPase domain" CG11898 16-Dec-15 2015_12 "viable,fertile" DRSC14432 IK -0.979546306 -3.244484535 0.344812767 -0.245373646 -1.805421876 0.492003521 FBgn0032922 CG9249 http://flybase.net/reports/FBgn0032922.html protein_coding_gene "0004395=hexaprenyldihydroxybenzoate methyltransferase activity, 0008425=2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity" "0006744=ubiquinone biosynthetic process, 0042060=wound healing, 0006743=ubiquinone metabolic process" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025714=Methyltransferase domain, IPR010233=Ubiquinone biosynthesis O-methyltransferase" CG9249 16-Dec-15 2015_12 ENSDARG00000069857(coq3) YOL096C(COQ3) WBGene00000763(coq-3) ENSXETG00000000799(COQ3) ENSMUSG00000028247(Coq3) ENSG00000132423(COQ3) "viable,fertile,visible" trichogen cell DRSC03168 K -0.091416109 -0.124518509 -0.906953214 0.343887644 1.157894776 1.925676626 FBgn0016076 vri vrille http://flybase.net/reports/FBgn0016076.html "FBgn0001927, FBgn0002670" protein_coding_gene "0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" "0006355=regulation of transcription, DNA-templated, 0045823=positive regulation of heart contraction, 0007622=rhythmic behavior, 0007623=circadian rhythm, 0007424=open tracheal system development, 0007275=multicellular organismal development, 0006351=transcription, DNA-templated, 0045475=locomotor rhythm, 0009987=cellular process, 0008407=chaeta morphogenesis, 0035317=imaginal disc-derived wing hair organization, 0010259=multicellular organismal aging" 0005634=nucleus "mat(2)earlyRS32, VRILLE, mel_vri, lethal(2)25Db, l(2)jf23, jf23, Vri, maternal effect early arrest G, DM16, VRI, mat(2)ea-G, CG14029, argo, l(2)25Db" IPR004827=Basic-leucine zipper domain CG14029 16-Dec-15 2015_12 ENSDARG00000043239 WBGene00000220(atf-2) " embryonic stage | >=4hr , embryonic stage | stage 13 , embryonic stage | stage 13-16 , embryonic stage | stage 14 , adult stage , pupal stage&&adult stage , larval stage | third instar , adult stage && oogenesis stage | stage S8 , embryonic stage | 0-8hr , embryonic stage | stage >=10 , embryonic stage | stage 15 , embryonic stage | stage 13-14 , embryonic stage | stage 16 , adult stage | male , embryonic stage | early " " posterior spiracle primordium

, anal pad

, epidermis | restricted

, ventral adult lateral neuron

, nurse cell

, dorsal adult lateral neuron

, adult head

, larval brain

, imaginal disc

, photoreceptor cell

, intercalary segment

, larval lateral neuron

, embryonic/larval proventriculus

, stomodeum

, embryonic/larval foregut

, amnioserosa

, inclusive hindgut primordium

, embryonic/larval tracheal system

,

ubiquitous , embryonic/larval digestive system

, follicle cell

" "visible,decreased cell size,somatic clone,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,lethal,locomotor rhythm defective,dominant,viable,female sterile,non-rescuable maternal effect,increased cell size,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "wing,wing margin,anterior,wing hair,embryonic dorsal epidermis,maternal effect,embryonic/larval tracheal system,head,denticle belt,wing vein L5,medial triple row,somatic clone,chaeta,eye,ommatidium,interommatidial bristle,eye photoreceptor cell stalk,extended germ band embryo,filzkorper,posterior scutellar bristle,egg,germline clone,adult heart,RU486 conditional,wing vein L2,embryonic head,embryonic/first instar larval cuticle,dorsal closure embryo,macrochaeta,supernumerary,wing disc,embryonic/larval salivary gland,embryonic/larval fat body,wing vein L3,mesothoracic tergum" DRSC23174 K 1.666600229 0.69112959 FBgn0004052 Z600 Z600 http://flybase.net/reports/FBgn0004052.html "FBgn0026799, FBgn0041755" protein_coding_gene "0005515=protein binding, 0030332=cyclin binding" "0045839=negative regulation of mitotic nuclear division, 0010972=negative regulation of G2/M transition of mitotic cell cycle, 0007369=gastrulation, 0007370=ventral furrow formation" 0005737=cytoplasm "DMZ60MEX, frustart, Frs, Fruhstart, fruhstart, frs, z600, 3.2, CG17962" CG17962 16-Dec-15 2015_12 " embryonic stage | stage 5-12 , embryonic stage | >=embryonic cycle 13 , embryonic stage | stage 4 , embryonic stage | 0-4 hr " " organism | dorsal

, organism | posterior

" " embryonic stage | 0-4 hr , embryonic stage | embryonic cycle 11-13 " "mitotic cell cycle defective,decreased cell number,visible,increased cell size,viable" "spermatogonial cyst,egg chamber,organism | embryonic cycle 16prd.RG1,wing hair,wing disc,wing" FBgn0266579 tau tau http://flybase.net/reports/FBgn0266579.html "FBgn0051057, FBgn0039535, FBgn0063056, FBgn0051058, FBgn0039533, FBgn0063637, FBgn0085323" protein_coding_gene 0008017=microtubule binding "0007017=microtubule-based process, 0046331=lateral inhibition, 1901215=negative regulation of neuron death, 0000226=microtubule cytoskeleton organization, 0061541=rhabdomere morphogenesis" "0030425=dendrite, 0030424=axon, 0005881=cytoplasmic microtubule, 0005875=microtubule associated complex" "CG12881, CG45110, CG34294, CG5606, dTau, d-tau, BcDNA:RE16764, CG31058, CG31057, Tau, dtau" "IPR001084=Microtubule associated protein, tubulin-binding repeat, IPR027324=Microtubule associated protein MAP2/MAP4/Tau" CG45110 16-Dec-15 2015_12 "ENSDARG00000045241,ENSDARG00000055052" WBGene00004212(ptl-1) "ENSXETG00000003240(MAPT),ENSXETG00000001624(MAP2)" " embryonic stage | late , adult stage , larval stage " " mesothoracic dorsal triscolopidial chordotonal organ dch3

, lamina

, eye disc

, ventral thoracic disc | restricted

, prothoracic dorsal triscolopidial chordotonal organ dch3

, abdominal 8 lateral chordotonal organ lch3

, neuron

, embryonic peripheral nervous system | restricted

, optic lobe

, medulla

, head

, embryonic brain

, abdominal lateral monoscolopidial chordotonal organ lch1

, abdominal lateral pentascolopidial chordotonal organ lch5

, abdominal 9 lateral chordotonal organ lch3/1

, ventral nerve cord

, metathoracic dorsal triscolopidial chordotonal organ dch3

, retina

, larval optic lobe

, morphogenetic furrow | posterior to

" FBgn0031485 CG9643 http://flybase.net/reports/FBgn0031485.html protein_coding_gene 0008168=methyltransferase activity "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR025714=Methyltransferase domain, IPR026635=Protein-lysine N-methyltransferase Efm4" CG9643 16-Dec-15 2015_12 ENSDARG00000014289(zgc:110805) YIL064W(SEE1) WBGene00017919(F29B9.1) ENSMUSG00000030960(Mettl10) ENSG00000203791(METTL10) "viable,fertile" DRSC27948 K -0.041487753 0.339278709 -0.414359299 -0.164747356 2.030279496 -0.117459148 FBgn0262511 Vha44 Vacuolar H+ ATPase 44kD subunit http://flybase.net/reports/FBgn0262511.html "FBgn0020611, FBgn0065466" protein_coding_gene "0046961=proton-transporting ATPase activity, rotational mechanism, 0015078=hydrogen ion transmembrane transporter activity, 0016820=hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances" "0007557=regulation of juvenile hormone biosynthetic process, 0015991=ATP hydrolysis coupled proton transport, 0015992=proton transport" "0005886=plasma membrane, 0033181=plasma membrane proton-transporting V-type ATPase complex, 0000221=vacuolar proton-transporting V-type ATPase, V1 domain, 0033180=proton-transporting V-type ATPase, V1 domain" "V-ATPase C subunit, Vacuolar H+ ATPase 44kD C subunit, l(2)6072, vha44, l(2)SH1339, CG8048, lethal (2) SH1339, Vacuolar H[+] ATPase 44 kDa subunit, C subunit, 6072, ATP6V1C, l(2)SH2 1339, vacuolar ATPase C-subunit, Vacuolar H[+] ATPase 44kD C subunit" "IPR004907=ATPase, V1 complex, subunit C" CG8048 16-Dec-15 2015_12 "ENSDARG00000023967(atp6v1c1a),ENSDARG00000035880(atp6v1c1b)" YKL080W(VMA5) WBGene00006920(vha-11) ENSXETG00000004115(atp6v1c1) ENSMUSG00000022295(Atp6v1c1) ENSG00000155097(ATP6V1C1) DRSC07572 K -1.187199705 0.540526949 -0.066840649 -1.305197831 1.89672237 1.899569193 FBgn0263144 bin3 bicoid-interacting protein 3 http://flybase.net/reports/FBgn0263144.html "FBgn0033073, FBgn0024490, FBgn0065556" protein_coding_gene "0001085=RNA polymerase II transcription factor binding, 0017069=snRNA binding, 0008168=methyltransferase activity" "0017148=negative regulation of translation, 0032259=methylation, 0042048=olfactory behavior" "Bicoid interacting protein 3, l(2)SH2 1014, Bicoid-interacting protein 3, l(2)SH1014, Bin3, CG8276, lethal (2) SH1014, bicoid interacting protein 3" "IPR025714=Methyltransferase domain, IPR010675=Bicoid-interacting 3, IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR024160=Bin3-type S-adenosyl-L-methionine binding domain" CG8276 16-Dec-15 2015_12 ENSDARG00000059461(mepce) ENSMUSG00000029726(Mepce) ENSG00000146834(MEPCE) " embryonic stage | 0-4hr , embryonic stage | early "

ubiquitous DRSC04919 IK 0.193016553 -1.977320536 0.648365009 -1.395320913 -0.631665308 -1.574000233 FBgn0014018 Rel Relish http://flybase.net/reports/FBgn0014018.html "FBgn0011469, FBgn0024223" protein_coding_gene "0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0005515=protein binding" "0009617=response to bacterium, 0002230=positive regulation of defense response to virus by host, 0006974=cellular response to DNA damage stimulus, 0045089=positive regulation of innate immune response, 0006963=positive regulation of antibacterial peptide biosynthetic process, 0050829=defense response to Gram-negative bacterium, 0061057=peptidoglycan recognition protein signaling pathway, 0045429=positive regulation of nitric oxide biosynthetic process, 0048813=dendrite morphogenesis, 0051607=defense response to virus, 0006955=immune response, 0045088=regulation of innate immune response, 2000647=negative regulation of stem cell proliferation, 0045087=innate immune response, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008063=Toll signaling pathway, 0034198=cellular response to amino acid starvation, 0007165=signal transduction, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0010628=positive regulation of gene expression, 0006967=positive regulation of antifungal peptide biosynthetic process, 0048935=peripheral nervous system neuron development" "0005719=nuclear euchromatin, 0005737=cytoplasm, 0005634=nucleus" "Rel-p110, Relish, RelA, immune response deficient 4, CG11992, positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | IMP, relish, ird, RELISH, NFkappaB, l(3)neo36, NF-kappaB, RELI, rel, Rel/NF-kappaB, ird4, unnamed, Nuclear factor NF-kappa-B p110 subunit, REL" "IPR002909=IPT domain, IPR011539=Rel homology domain (RHD), DNA-binding domain, IPR013783=Immunoglobulin-like fold, IPR014756=Immunoglobulin E-set, IPR008967=p53-like transcription factor, DNA-binding, IPR000451=NF-kappa-B/Dorsal, IPR002110=Ankyrin repeat, IPR020683=Ankyrin repeat-containing domain" CG11992 16-Dec-15 2015_12 "ENSDARG00000038687(LOC100329567),ENSDARG00000039473(nfkb2)" "ENSXETG00000021325(NFKB1),ENSXETG00000000013(nfkb2)" "ENSMUSG00000028163(Nfkb1),ENSMUSG00000025225(Nfkb2)" "ENSG00000077150(NFKB2),ENSG00000109320(NFKB1)" " embryonic stage | early , adult stage | female , adult stage && oogenesis stage " nurse cell

"immune response defective,viable,recessive,neuroanatomy defective,visible,fertile,lethal,increased cell death,cold sensitive,dominant,short lived,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,macrochaeta,mesothoracic tergum,ectopic,adult brain,lamina,cold sensitive,dorsocentral bristle,intestinal stem cell,adult posterior midgut epithelium" DRSC16819 E 0.496334294 1.222535901 -0.400910449 2.25077341 0.302072844 -0.43303548 FBgn0262871 lute lute http://flybase.net/reports/FBgn0262871.html "FBgn0038501, FBgn0062117, FBgn0038500" protein_coding_gene 0022008=neurogenesis "CG43226, CG5319, anon-WO0118547.289, CG14333" "IPR011333=POZ domain, IPR012983=PHR, IPR000210=BTB/POZ domain, IPR011705=BTB/Kelch-associated" CG43226 16-Dec-15 2015_12 "ENSDARG00000052227,ENSDARG00000005544(btbd3),ENSDARG00000032369(btbd6b),ENSDARG00000062559(LOC100330589)" WBGene00006415(tag-30) ENSXETG00000002336(BTBD3) "ENSMUSG00000062098(Btbd3),ENSMUSG00000002803(Btbd6)" "ENSG00000132640(BTBD3),ENSG00000184887(BTBD6)" DRSC25911 K 0.730624677 -0.310276427 -0.779626706 -0.139702429 2.154221261 -0.130102616 FBgn0017456 Ubc84D Ubiquitin conjugating enzyme 84D http://flybase.net/reports/FBgn0017456.html protein_coding_gene 0004842=ubiquitin-protein transferase activity 0000209=protein polyubiquitination "ubc, UbcD84, CG12799, ubiquitin conjugating enzyme" "IPR023313=Ubiquitin-conjugating enzyme, active site, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR000608=Ubiquitin-conjugating enzyme E2" CG12799 16-Dec-15 2015_12 WBGene00006713(ubc-18) viable DRSC25384 IK 1.708094409 0.802952012 1.24885621 0.383343257 6.682892325 6.840966 FBgn0003714 tko technical knockout http://flybase.net/reports/FBgn0003714.html protein_coding_gene 0003735=structural constituent of ribosome "0007638=mechanosensory behavior, 0007605=sensory perception of sound, 0009612=response to mechanical stimulus, 0007619=courtship behavior, 0006412=translation, 0008049=male courtship behavior, 0001666=response to hypoxia" 0005763=mitochondrial small ribosomal subunit "l(1)3Ab, rps12, CG7925, S12, Tko, mt-rps12, l(1)tko, MRP-S12, mitochondrial ribosomal protein S12, MRPS12, EG:BACH59J11.1, mRpS12, mitoribosomal protein S12" "IPR012340=Nucleic acid-binding, OB-fold, IPR006032=Ribosomal protein S12/S23, IPR005679=Ribosomal protein S12, bacteria" CG7925 16-Dec-15 2015_12 ENSDARG00000069488 YNR036C(MRPS12) WBGene00011391(T03D8.2) ENSXETG00000005326(mrps12) ENSMUSG00000045948(Mrps12) ENSG00000128626(MRPS12) "lethal,some die during third instar larval stage,some die during second instar larval stage,wild-type,viable,female sterile,recessive,developmental rate defective,bang sensitive,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,visible,courtship behavior defective,male,mating defective,auditory perception defective,female,cold sensitive,chemical sensitive,neurophysiology defective,male limited,behavior defective" "egg,adult antennal lobe projection neuron DL1 adPN,somatic clone,gamma Kenyon cell,macrochaeta" DRSC27125 K 0.400620664 -0.898350641 -1.15436026 0.125075653 1.423632656 2.14779984 FBgn0030350 SelG Selenoprotein G http://flybase.net/reports/FBgn0030350.html FBgn0064979 protein_coding_gene "0032469=endoplasmic reticulum calcium ion homeostasis, 0045454=cell redox homeostasis, 0010470=regulation of gastrulation, 0008340=determination of adult lifespan, 0001700=embryonic development via the syncytial blastoderm, 0007350=blastoderm segmentation" "0043231=intracellular membrane-bounded organelle, 0005794=Golgi apparatus" "dselG, Seleno-protein G, unnamed, dSelK, dselK, BcDNA:GH03581, G-rich, G-rich protein, CG1844, SelK" IPR024491=Selenoprotein SelK/SelG CG1844 16-Dec-15 2015_12 "developmental rate defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" DRSC19808 I 3.865047298 1.246750564 0.351680904 0.676829115 -0.680738177 -0.465606497 FBgn0037492 CG10050 http://flybase.net/reports/FBgn0037492.html protein_coding_gene IPR005636=DTW CG10050 16-Dec-15 2015_12 ENSXETG00000017583(TEgg008m05.1) ENSMUSG00000024505(Dtwd2) ENSG00000169570(DTWD2) viable DRSC12501 I 1.825219104 0.247793754 0.142794582 0.419107609 -0.229254431 -0.125008409 FBgn0032518 RpL24 Ribosomal protein L24 http://flybase.net/reports/FBgn0032518.html "FBgn0026273, FBgn0026275" protein_coding_gene 0003735=structural constituent of ribosome "0006412=translation, 0000022=mitotic spindle elongation, 0007052=mitotic spindle organization, 0051298=centrosome duplication" "0005840=ribosome, 0022625=cytosolic large ribosomal subunit" "Rpl24, anon-EST:Posey37, anon-EST:Posey242, CG9282, RL24_DROME, L24, Rp L24" "IPR011017=TRASH domain, IPR000988=Ribosomal protein L24e-related, IPR023441=Ribosomal protein L24e domain" CG9282 16-Dec-15 2015_12 ENSDARG00000015490(rpl24) "YGR148C(RPL24B),YGL031C(RPL24A)" WBGene00004436(rpl-24.1) ENSXETG00000008052(RPL24) ENSMUSG00000022601(Rpl24) "ENSG00000114391(RPL24),ENSG00000181524" DRSC28724 IEK -2.36034726 -1.632061247 0.017070946 -3.471017496 1.63370372 2.705123609 FBgn0022986 qkr58E-1 quaking related 58E-1 http://flybase.net/reports/FBgn0022986.html protein_coding_gene "0003729=mRNA binding, 0003723=RNA binding" "0022008=neurogenesis, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0005634=nucleus" "QKR58E-1, KH-domain, qkr-58-E, qrk58E-1, CG3613" "IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG3613 16-Dec-15 2015_12 "ENSDARG00000069469(khdrbs2),ENSDARG00000070475(khdrbs1b),ENSDARG00000052856(khdrbs1a),ENSDARG00000063548" "WBGene00013325(Y57G11C.36),WBGene00019509(K07H8.9)" "ENSXETG00000004451(KHDRBS2),ENSXETG00000009227(KHDRBS3),ENSXETG00000005246(pcbp2)" "ENSMUSG00000022332(Khdrbs3),ENSMUSG00000026058(Khdrbs2),ENSMUSG00000028790(Khdrbs1)" "ENSG00000131773(KHDRBS3),ENSG00000112232(KHDRBS2),ENSG00000121774(KHDRBS1)" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC04709 I -1.4465963 2.040712099 0.261037455 -0.355408436 -0.070910723 -0.59231784 FBgn0002573 sens senseless http://flybase.net/reports/FBgn0002573.html "FBgn0011709, FBgn0027151, FBgn0036355, FBgn0052120" protein_coding_gene "0043565=sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043425=bHLH transcription factor binding, 0008270=zinc ion binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" "0043066=negative regulation of apoptotic process, 0045872=positive regulation of rhodopsin gene expression, 0007423=sensory organ development, 0008594=photoreceptor cell morphogenesis, 0016360=sensory organ precursor cell fate determination, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0008407=chaeta morphogenesis, 0042051=compound eye photoreceptor development, 0048666=neuron development, 0045465=R8 cell differentiation, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007411=axon guidance, 0045464=R8 cell fate specification, 0048813=dendrite morphogenesis, 0046530=photoreceptor cell differentiation, 0007422=peripheral nervous system development" "0005700=polytene chromosome, 0005634=nucleus" "sen, 1228/04, Ly-1, Sens, Gfi1, Ly, CG10714, CG32120, Senseless, Sen, senseless, Lyra, Sensless, sense, SENS, Ss, l(3)70Ad, sensesless" "IPR001878=Zinc finger, CCHC-type, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG32120 16-Dec-15 2015_12 WBGene00015138(B0310.2) " embryonic stage | stage 11-12 , embryonic stage | stage >=11 , embryonic stage | stage 11-13 , embryonic stage | stage 10 , embryonic stage | stage 10-12 " " external sensory organ precursor cell I

, adult salivary gland primordium

, salivary gland

, external sensory organ precursor cell IIa

, external sensory organ precursor cell IIb

, lateral ectoderm | restricted

, sensory mother cell

, embryonic peripheral nervous system | restricted

" " embryonic stage | stage 11-14 , embryonic stage | stage 10-14 , larval stage | third instar , embryonic stage | stage >=11 " " salivary gland

, embryonic peripheral nervous system | restricted

, Johnston's organ

, adult salivary gland primordium

, metathoracic femoral chordotonal organ

, sensory mother cell

, mesothoracic femoral chordotonal organ

, photoreceptor cell R8

, prothoracic femoral chordotonal organ

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

" "visible,wild-type,lethal,recessive,cell autonomous,somatic clone,increased cell death,neuroanatomy defective,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "scutellar bristle,ectopic,chordotonal organ,external sensory organ,multidendritic neuron,photoreceptor cell R8,somatic clone,cell non-autonomous,ommatidium,photoreceptor cell R7,chaeta,cell autonomous,tormogen cell,microchaeta,photoreceptor cell R2,photoreceptor cell R5,embryonic/larval salivary gland,dorsal row,ventral row,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,supernumerary,eo neuron,thecogen cell,trichogen cell,mechanosensory chaeta,postorbital bristle,trichome of the posterior wing margin,embryonic/larval oenocyte precursor,medulla,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & neuronS122804),PNS glial cell,wing margin,wing,anterior wing margin,posterior wing margin,eye,macrochaeta,sensillum campaniformium of dorsal radius,wing sensillum,sternopleural bristle,leg sensillum,leg,distal,scutum,wing & chaetadpp.blk1,leg & chaetadpp.blk1,scutum & chaetadpp.blk1,mesothoracic bristle,microchaeta & scutellum | ectopicC5,mechanosensory sensory organ,metathoracic bristle,prothoracic tarsal bristle,interommatidial bristle,secondary pigment cell,tertiary pigment cell,axon & photoreceptor cell R7 | somatic clonetub.PU" DRSC09263 K -2.589957165 -1.789978122 FBgn0027535 botv brother of tout-velu http://flybase.net/reports/FBgn0027535.html protein_coding_gene "0008375=acetylglucosaminyltransferase activity, 0001888=glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, 0042328=heparan sulfate N-acetylglucosaminyltransferase activity" "0008101=decapentaplegic signaling pathway, 0007224=smoothened signaling pathway, 0007367=segment polarity determination, 0006024=glycosaminoglycan biosynthetic process, 0015014=heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, 0006044=N-acetylglucosamine metabolic process, 0015012=heparan sulfate proteoglycan biosynthetic process, 0030201=heparan sulfate proteoglycan metabolic process, 0016055=Wnt signaling pathway" "0005794=Golgi apparatus, 0016021=integral component of membrane, 0005783=endoplasmic reticulum" "DExt3, CG15110, DEXT3, dExt3, Drosophila Ext-like 3, brother of tout-velo, BcDNA:LD21192, DEXTL3, Dextl3, brother-of-tout-velu, brother of tout velu, Extl3, Botv, Brother of tout-velu" "IPR027674=Exostosin 3/Exostosin-like 3, IPR029044=Nucleotide-diphospho-sugar transferases, IPR015338=Exostosin , C-terminal, IPR004263=Exostosin-like" CG15110 16-Dec-15 2015_12 ENSDARG00000026811(extl3) WBGene00004361(rib-2) ENSXETG00000000117(extl3) ENSMUSG00000021978(Extl3) ENSG00000012232(EXTL3) " adult stage | male , embryonic stage -- adult stage , adult stage | female " head

"lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,body color defective" "eye,leg,imaginal disc,wing disc,wing,somatic clone,wing vein,wing margin,embryonic/first instar larval cuticle,germline clone,maternal effect,denticle belt,mesothoracic tergum" FBgn0261930 vnd ventral nervous system defective http://flybase.net/reports/FBgn0261930.html "FBgn0003986, FBgn0002942, FBgn0084188" protein_coding_gene "0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding" "0009953=dorsal/ventral pattern formation, 0007400=neuroblast fate determination, 0006357=regulation of transcription from RNA polymerase II promoter, 0007419=ventral cord development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0010629=negative regulation of gene expression, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007417=central nervous system development, 0021782=glial cell development, 0014019=neuroblast development, 0007389=pattern specification process, 0007398=ectoderm development, 0007420=brain development, 0006355=regulation of transcription, DNA-templated" 0005634=nucleus "VND, ventral neuroblasts defective, CG6172, Vnd, l(1)EC6, ventral nerve cord defective, ventral nervous system condensation defective, EC6, nk-2, dNK-2, Dm-NK2, HDC16822, l(1)EA142, NK2, l(1)GA100, l(1)VE769, Ventral nervous system defective, vnd/NK-2, l(1)GA122, l(1)RC24, ventral neurons defective, lab, Nkx2, l(1)VA208, NK-2, EG:118B3.1, l(1)1Bf, Dm vnd" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain" CG6172 16-Dec-15 2015_12 " embryonic stage | stage 11 , embryonic stage | stage 8-11 , embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 7-8 , embryonic stage | stage 7,8 " " neuroblast NB1-2

, neuroblast NB2-1

, ventral neurogenic region | restricted

, neuroblast NB4-1

, central nervous system | restricted

, posterior embryonic/larval midgut

, ventral neurogenic region

, neuroblast | subset

, neuroblast NB2-2

, neuroblast NB1-1

, anterior embryonic/larval midgut

, neuroblast NB6-2

, neuroblast NB5-2

, neuroblast NB3-1

, neuroblast NB6-1

, ventral midline

, neuroblast MP2

, neuroblast NB5-1

, neuroblast NB7-2

, neuroblast NB7-1

" " embryonic stage | stage 11 , embryonic stage | stage 8-9 , embryonic stage | stage 9-11 , embryonic stage | stage 8 , embryonic stage | cellular blastoderm " " pCC neuron

, U neuron

, embryonic neuron | subset

, neuroblast | subset

, procephalic neuroblast | subset & ventral

, protocerebral neuroblast | subset

, tritocerebral neuroblast | subset

, ventral midline

, ventral neurogenic region && embryonic antennal segment | ventral & restricted

, deuterocerebral neuroblast | subset

, ventral neurogenic region | restricted

, ventral neurogenic region && embryonic intercalary segment | ventral & restricted

, ventral neurogenic region && embryonic ocular segment | ventral & restricted

" DRSC18849 I -0.241859869 2.117121463 0.355150963 0.282667908 0.720278343 0.92449675 FBgn0026309 aft adrift http://flybase.net/reports/FBgn0026309.html FBgn0028739 protein_coding_gene 0008168=methyltransferase activity "0007424=open tracheal system development, 0016477=cell migration, 0007426=tracheal outgrowth, open tracheal system, 0032259=methylation" 0005634=nucleus "CG5032, EG:52C10.7" "IPR029063=S-adenosyl-L-methionine-dependent methyltransferase, IPR002877=Ribosomal RNA methyltransferase FtsJ domain, IPR025807=Adrift-type ribose 2-O-methyltransferase domain" CG5032 16-Dec-15 2015_12 ENSDARG00000036345(ftsjd1) ENSXETG00000015884(FTSJD1) ENSMUSG00000046441(Ftsjd1) ENSG00000180917(FTSJD1) " embryonic stage | stage >=12 , embryonic stage , embryonic stage | syncytial blastoderm , embryonic stage | stage >=11 " " embryonic/larval ganglionic branch | restricted

, gonad

,

ubiquitous , embryonic/larval tracheal system

" " embryonic stage , embryonic stage | early " " epidermis

, gonad

, embryonic brain

" "wild-type,viable" embryonic/larval ganglionic branch FBgn0263773 fok fledgling of Klp38B http://flybase.net/reports/FBgn0263773.html "FBgn0020303, FBgn0022079, FBgn0032844, FBgn0262096" protein_coding_gene "l(2)k07614, noncoding_3938, CG43690, unnamed, CG10746, Fok, 38B.11, CG42849" CG43690 16-Dec-15 2015_12 " embryonic stage&&adult stage , embryonic stage | >=4 hr , adult stage " DRSC23907 IK -1.656657316 0.333239024 -0.558448272 0.41287203 0.968085545 2.277447487 FBgn0027111 miple1 midkine and pleiotrophin 1 http://flybase.net/reports/FBgn0027111.html FBgn0027731 protein_coding_gene "0008201=heparin binding, 0008083=growth factor activity" "0048332=mesoderm morphogenesis, 0008340=determination of adult lifespan" 0005576=extracellular region "CG1221, Miple, anon-EST:Posey203, miple1, miple" "IPR020090=Pleiotrophin/Midkine, C-terminal domain" CG1221 16-Dec-15 2015_12 "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC08722 E 0.335569321 1.166520862 1.718786772 -0.049063239 -0.556742077 -0.26566344 FBgn0085382 CG34353 http://flybase.net/reports/FBgn0085382.html "FBgn0039546, FBgn0040615, FBgn0039549, FBgn0039547, FBgn0039545, FBgn0039550, FBgn0039548" protein_coding_gene 0042332=gravitaxis "CG12427, CG5566, CG12875, CG12874, CG12873, CG5572, CG12274" "IPR007110=Immunoglobulin-like domain, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013783=Immunoglobulin-like fold, IPR013151=Immunoglobulin" CG34353 16-Dec-15 2015_12 WBGene00006942(wrk-1) "gravitaxis defective,viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC14563 K -0.037482181 0.020583236 -0.135663034 -0.190642201 2.445820845 -0.480378421 FBgn0025578 Lcp9 Larval cuticle protein 9 http://flybase.net/reports/FBgn0025578.html FBgn0035062 protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" "0008363=larval chitin-based cuticle development, 0040003=chitin-based cuticle development" "0031012=extracellular matrix, 0005576=extracellular region" "LCP9, CG16914, lcp9, DmelLcp9" "IPR000618=Insect cuticle protein, IPR031311=Chitin-binding type R&R consensus" CG16914 16-Dec-15 2015_12 viable DRSC04287 I -0.327492265 -1.653052684 -1.240325872 0.003798219 -0.601591682 -0.666885759 FBgn0026378 Rep Rab escort protein http://flybase.net/reports/FBgn0026378.html protein_coding_gene "0017137=Rab GTPase binding, 0004663=Rab geranylgeranyltransferase activity" "0006886=intracellular protein transport, 0016192=vesicle-mediated transport, 0007269=neurotransmitter secretion, 0018344=protein geranylgeranylation" "0008021=synaptic vesicle, 0000922=spindle pole, 0016020=membrane, 0005737=cytoplasm, 0005968=Rab-protein geranylgeranyltransferase complex, 0048471=perinuclear region of cytoplasm, 0005818=aster" "Rab escort protein homolog, rab escort protein, CG8432, REP" "IPR001738=Rab protein geranylgeranyltransferase component A, IPR018203=GDP dissociation inhibitor" CG8432 16-Dec-15 2015_12 "ENSDARG00000003845(chm),ENSDARG00000054403" YOR370C(MRS6) WBGene00022051(rep-1) ENSXETG00000017820() "ENSMUSG00000025531(Chm),ENSMUSG00000078185(Chml)" "ENSG00000188419(CHM),ENSG00000203668(CHML)" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC07526 K -0.486307421 -0.918564052 -0.99137153 -0.791171118 2.081170851 -0.613765693 FBgn0013746 alien alien http://flybase.net/reports/FBgn0013746.html "FBgn0027056, FBgn0063164" protein_coding_gene "0035257=nuclear hormone receptor binding, 0016922=ligand-dependent nuclear receptor binding, 0003714=transcription corepressor activity, 0005515=protein binding, 0042803=protein homodimerization activity" "0010388=cullin deneddylation, 0007281=germ cell development, 0048142=germarium-derived cystoblast division, 0007095=mitotic G2 DNA damage checkpoint, 0051726=regulation of cell cycle, 0022008=neurogenesis, 0050821=protein stabilization, 0048140=male germ-line cyst encapsulation, 0045892=negative regulation of transcription, DNA-templated, 0006909=phagocytosis, 0036099=female germ-line stem cell maintenance" "0008180=COP9 signalosome, 0008231=repressor ecdysone receptor complex" "CH2, CG9556, BcDNA:LD10463, Csn2, CSN2, Dch2, d-Alien, DCH2, Drosophila COP9 signalosome homolog 2, COP9 complex homolog subunit 2, Alien" "IPR011990=Tetratricopeptide-like helical domain, IPR000717=Proteasome component (PCI) domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR013143=PCI/PINT associated module" CG9556 16-Dec-15 2015_12 ENSDARG00000004785(cops2) WBGene00000814(csn-2) ENSXETG00000008784(cops2) ENSMUSG00000027206(Cops2) ENSG00000166200(COPS2) embryonic stage " apodeme &&of pharynx

, abdominal 1--7 intrasegmental apodeme 2

, intersegmental apodeme

, intrasegmental apodeme

, abdominal 1--7 intersegmental apodeme

, abdominal 1--7 intrasegmental apodeme 1

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC03482 K -0.360968071 -0.198849767 -0.142635149 0.796914536 1.889659677 3.183688602 FBgn0024330 MED6 Mediator complex subunit 6 http://flybase.net/reports/FBgn0024330.html "FBgn0027700, FBgn0037748, FBgn0063159" protein_coding_gene "0005515=protein binding, 0003713=transcription coactivator activity, 0001104=RNA polymerase II transcription cofactor activity" "0045824=negative regulation of innate immune response, 0046331=lateral inhibition, 0007406=negative regulation of neuroblast proliferation, 0006367=transcription initiation from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0050829=defense response to Gram-negative bacterium" "0005737=cytoplasm, 0005634=nucleus, 0016592=mediator complex" "Med6, p35, anon-EST:Posey279, dMed6, dMED6, Mediator, Trap32, dTRAP32, BcDNA:LD15729, CG9473, med6" "IPR016820=Mediator complex, subunit Med6, metazoa/plant, IPR007018=Mediator complex, subunit Med6" CG9473 16-Dec-15 2015_12 ENSDARG00000034734(med6) WBGene00003164(mdt-6) ENSXETG00000002222(MED6) ENSMUSG00000002679(Med6) ENSG00000133997(MED6) "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,female sterile,germline clone,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage,lethal" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,follicle cell,somatic clone,eye,imaginal disc,wing disc" DRSC16500 IK 0.112603655 2.266391193 -0.306104213 0.129206078 1.546150606 0.348712307 FBgn0267821 da daughterless http://flybase.net/reports/FBgn0267821.html "FBgn0000413, FBgn0022036" protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0001012=RNA polymerase II regulatory region DNA binding, 0043565=sequence-specific DNA binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0042803=protein homodimerization activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0008134=transcription factor binding, 0046982=protein heterodimerization activity" "0008407=chaeta morphogenesis, 0007530=sex determination, 0048663=neuron fate commitment, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007541=sex determination, primary response to X:A ratio, 0006974=cellular response to DNA damage stimulus, 0045893=positive regulation of transcription, DNA-templated, 0061382=Malpighian tubule tip cell differentiation, 0045464=R8 cell fate specification, 0035019=somatic stem cell maintenance, 0007423=sensory organ development, 0061101=neuroendocrine cell differentiation, 0048477=oogenesis, 0007422=peripheral nervous system development, 0016330=second mitotic wave involved in compound eye morphogenesis, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated, 0030707=ovarian follicle cell development, 0007399=nervous system development" "0005634=nucleus, 0005667=transcription factor complex" "l(2)k08611, lethal (2) k08611, bHLHb22, CG5102, DA, Daughterless, l(2)31Ea, 5102, daughter-less, Da" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG5102 16-Dec-15 2015_12 "ENSDARG00000004714(tcf12),ENSDARG00000052383,ENSDARG00000005915(tcf3)" "ENSXETG00000016563(TCF12),ENSXETG00000019086(TCF4)" "ENSMUSG00000053477(Tcf4),ENSMUSG00000032228(Tcf12),ENSMUSG00000020167(Tcf3)" "ENSG00000140262(TCF12),ENSG00000196628(TCF4),ENSG00000071564(TCF3)" DRSC03517 K -0.214533458 -0.481346584 -0.38401039 -0.59714716 1.88625726 0.524335697 FBgn0086675 fne found in neurons http://flybase.net/reports/FBgn0086675.html "FBgn0040222, FBgn0047242, FBgn0030436, FBgn0045795, FBgn0052646, FBgn0063046" protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0008266=poly(U) RNA binding" "0051252=regulation of RNA metabolic process, 0008049=male courtship behavior" 0005737=cytoplasm "lincRNA.985, BcDNA:RE25290, CG4396, cg4396, found in neurons, MRE28, Fne, CR32646, BcDNA:HL02010, FNE, BEST:HL02010, Found in NEurons, Found in neurons" "IPR002343=Paraneoplastic encephalomyelitis antigen, IPR000504=RNA recognition motif domain, IPR006548=Splicing factor ELAV/HuD, IPR012677=Nucleotide-binding alpha-beta plait domain" CG4396 16-Dec-15 2015_12 "ENSDARG00000040732(zgc:91918),ENSDARG00000045639(elavl4),ENSDARG00000014420(elavl3),ENSDARG00000038695(elavl1),ENSDARG00000016405(hug)" YCL011C(GBP2) WBGene00001368(exc-7) "ENSXETG00000008680(ELAVL4),ENSXETG00000016741(elval3),ENSXETG00000009387(ELAVL2),ENSXETG00000008752(elavl1)" "ENSMUSG00000008489(Elavl2),ENSMUSG00000028546(Elavl4),ENSMUSG00000003410(Elavl3),ENSMUSG00000040028(Elavl1)" "ENSG00000107105(ELAVL2),ENSG00000162374(ELAVL4),ENSG00000196361(ELAVL3),ENSG00000066044(ELAVL1)" DRSC20332 IK 0.642261473 -2.601554176 -0.358408268 -0.67421499 -1.500464561 2.034815472 FBgn0039509 bigmax bigmax http://flybase.net/reports/FBgn0039509.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0046983=protein dimerization activity" "0008343=adult feeding behavior, 0006355=regulation of transcription, DNA-templated, 0048102=autophagic cell death, 0048813=dendrite morphogenesis, 0035071=salivary gland cell autophagic cell death, 0007517=muscle organ development, 0006351=transcription, DNA-templated" 0005634=nucleus "CG3350, Bigmax, bHLHd13, DmMlx, mlx, big max, BIGMAX, cg3350, Mlx" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG3350 16-Dec-15 2015_12 ENSDARG00000037891(mlx) YBL103C(RTG3) WBGene00003510(mxl-2) ENSXETG00000012035(MLX) ENSMUSG00000017801(Mlx) ENSG00000108788(MLX) "majority die during pharate adult stage,developmental rate defective,lethal,conditional,viable,fertile,partially lethal" DRSC27542 K -0.293881812 0.676708658 -0.386991031 -0.226091023 -1.549114853 -1.001737909 FBgn0022943 Cbp20 cap binding protein 20 http://flybase.net/reports/FBgn0022943.html protein_coding_gene "0003729=mRNA binding, 0000166=nucleotide binding, 0000339=RNA cap binding" "0035195=gene silencing by miRNA, 0000398=mRNA splicing, via spliceosome, 0045071=negative regulation of viral genome replication, 0045292=mRNA cis splicing, via spliceosome, 0030422=production of siRNA involved in RNA interference" "0005634=nucleus, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005846=nuclear cap binding complex, 0071013=catalytic step 2 spliceosome, 0005875=microtubule associated complex" "CBP20, CG12357, cbp20" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR027157=Nuclear cap-binding protein subunit 2" CG12357 16-Dec-15 2015_12 ENSDARG00000014898(ncbp2) YPL178W(CBC2) WBGene00009141(ncbp-2) ENSXETG00000019384(ncbp2) ENSMUSG00000022774(Ncbp2) ENSG00000114503(NCBP2) "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16601 E -1.373373642 0.163633029 -0.665405551 -2.095003137 -0.705169843 0.013278262 FBgn0011674 insc inscuteable http://flybase.net/reports/FBgn0011674.html "FBgn0010601, FBgn0013468, FBgn0015387" protein_coding_gene "0008093=cytoskeletal adaptor activity, 0005515=protein binding" "0007400=neuroblast fate determination, 0061382=Malpighian tubule tip cell differentiation, 0040001=establishment of mitotic spindle localization, 0050829=defense response to Gram-negative bacterium, 0007423=sensory organ development, 0008105=asymmetric protein localization, 0007422=peripheral nervous system development, 0008356=asymmetric cell division, 0008104=protein localization, 0007010=cytoskeleton organization, 0051960=regulation of nervous system development, 0009786=regulation of asymmetric cell division, 0045175=basal protein localization, 0007525=somatic muscle development, 0045176=apical protein localization, 0006403=RNA localization, 0045167=asymmetric protein localization involved in cell fate determination, 0055059=asymmetric neuroblast division" "0005938=cell cortex, 0045177=apical part of cell, 0045179=apical cortex, 0005737=cytoplasm" "fata morgana, fam, CG11312, Inscuteable, inscrutable, Inscutable, l(2)k12405, l(2)05475, not enough muscles, 25/17, INSC, Ins, nem, Insc" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical" CG11312 16-Dec-15 2015_12 ENSMUSG00000048782(Insc) ENSG00000188487(INSC) " embryonic stage | 3-12 hr , embryonic stage | stage <=14 , embryonic stage | stage 13-15 , embryonic stage | stage 10 , embryonic stage | stage 9-11 , embryonic stage | stage 10-12 , embryonic stage | stage >=15 , embryonic stage | stage 4 , embryonic stage | 4-20 hr , embryonic stage | stage 11-13 , adult stage , embryonic stage | stage 10-13 , embryonic stage , embryonic stage | stage 6 " " embryonic central nervous system

, embryonic/larval midgut

, ganglion mother cell

, ventral neurogenic region

, posterior midgut proper primordium

, embryonic/larval hindgut

, procephalic neurogenic region

, sense organ | precursor

, embryonic peripheral nervous system | restricted

, gastric caecum

, myoblast &&of larval muscle system

, embryonic brain

, anterior midgut proper primordium

, embryonic/larval trachea

, Malpighian tubule

, ventral nerve cord | restricted

, neuroblast

, C1 chordotonal organ precursor cell

, embryonic/larval pharynx

" " embryonic stage | stage 13-15 , embryonic stage | stage 10-12 , embryonic stage | stage >=15 , embryonic stage | stage 10-13 , embryonic stage | stage 11-13 , embryonic stage | stage 6 , embryonic stage , embryonic stage | stage 10 , embryonic stage | stage 9-11 , pupal stage | >20 hr " " embryonic/larval midgut

, anterior midgut proper primordium

, embryonic/larval pharynx

, myoblast &&of larval muscle system

, sense organ | precursor

, embryonic/larval hindgut

, procephalic neurogenic region

, ventral nerve cord | restricted

, ganglion mother cell

, posterior midgut proper primordium

, neuroblast

, dorsal mesothoracic disc | restricted

, Malpighian tubule

, gastric caecum

, embryonic/larval trachea

" "lethal,recessive,viable,fertile,some die during immature adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,wild-type,neuroanatomy defective,somatic clone,cell polarity defective" "wing,presumptive embryonic/larval peripheral nervous system,chordotonal organ,imaginal disc,scutellar bristle,tormogen cell,trichogen cell,embryonic/larval somatic muscle,pericardial cell,mesothoracic lateral longitudinal muscle,abdominal dorsal oblique muscle,abdominal dorsal transverse muscle,abdominal lateral transverse muscle,abdominal adult muscle precursor cell,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,mesothoracic ventral oblique muscle,abdominal ventral oblique muscle,somatic muscle,hypodermal muscle of larval abdominal 9,abdominal lateral pentascolopidial chordotonal organ,metathoracic ventral oblique muscle,abdominal ventral longitudinal muscle,metathoracic ventral longitudinal muscle,mesothoracic ventral longitudinal muscle,mesothoracic segment border muscle,metathoracic segment border muscle,abdominal segment border muscle,abdominal lateral longitudinal muscle,Malpighian tubule tip cell,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,abdominal dorsal acute muscle,dorsal oblique muscle,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle,abdominal anterior ventral multidendritic neuron vdaa,abdominal vesA neuron,abdominal v'esA neuron,abdominal vesB neuron,abdominal v'esB neuron,abdominal vesC neuron,ventral multidendritic neuron vdaA,ventral multidendritic neuron vdaB,ventral multidendritic neuron vdaC,ventral multidendritic neuron vdaD,abdominal ventral bipolar neuron vbp,adult muscle precursor cell,ganglion mother cell GMC1-1a,ganglion mother cell GMC4-2a,pCC neuron,RP2sib neuron,abdominal ventral multidendritic neuron,neuroblast,RP2 motor neuron,aCC neuron,U neuron,EL neuron,presumptive embryonic/larval central nervous system,presumptive embryonic/larval digestive system,external sensory organ precursor cell I,ventral nerve cord primordium" FBgn0001981 esg escargot http://flybase.net/reports/FBgn0001981.html "FBgn0000445, FBgn0011711, FBgn0015967" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0046872=metal ion binding" "0006357=regulation of transcription from RNA polymerase II promoter, 0007489=maintenance of imaginal histoblast diploidy, 0001709=cell fate determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0042048=olfactory behavior, 0032876=negative regulation of DNA endoreduplication, 0035156=fusion cell fate specification, 0007427=epithelial cell migration, open tracheal system, 0007424=open tracheal system development, 0001708=cell fate specification, 0030718=germ-line stem cell maintenance, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0035220=wing disc development, 0035147=branch fusion, open tracheal system, 0007422=peripheral nervous system development, 0007417=central nervous system development, 0055059=asymmetric neuroblast division, 0048076=regulation of compound eye pigmentation, 0042332=gravitaxis, 0035215=genital disc development" 0005634=nucleus "l(2)esg, esgargot, l(2)4B7, shof, Esgargot, l(2)35Ce, flg, Esg, BG:DS07851.7, wizard, shut off, dgl, CG3758, 4B7, br43, D.m.Escargot, l35Ce, double glazed, wiz, fleabag, l(2)br43, l(2)07082, Escargot, Fusion-1" "IPR015880=Zinc finger, C2H2-like, IPR029795=SNAIL family, IPR007087=Zinc finger, C2H2, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG3758 16-Dec-15 2015_12 ENSDARG00000031243(snai3) "YPR015C(),YPR013C()" WBGene00022592(ZC328.2) "ENSMUSG00000060257,ENSMUSG00000048385(Scrt1)" " larval stage | third instar , embryonic stage | stage 14 , embryonic stage | stage 14-16 , embryonic stage | stage 11 , embryonic stage | stage 16 , embryonic stage | stage 12 , embryonic stage && pupal stage , embryonic stage | stage 8-9 , embryonic stage " " central nervous system

, histoblast nest

, ventral midline

, dorsal mesothoracic disc | presumptive

, head

, ventral thoracic disc | presumptive

, dorsal metathoracic disc primordium

, embryonic/larval trachea

, ventral mesothoracic disc

, dorsal metathoracic disc

, histoblast

, dorsal ridge

, imaginal disc

, peripheral nervous system

, dorsal mesothoracic disc

, ventral neurogenic region

, ventral metathoracic disc

, genital disc

, ventral prothoracic disc

, ectoderm

" " embryonic stage | stage 13 , embryonic stage | stage 15 , embryonic stage | stage 5 " " tracheal fusion cell

, dorsal mesothoracic disc | presumptive

, ventral thoracic disc primordium | restricted & proximal

, dorsal mesothoracic disc

, dorsal metathoracic disc | presumptive

, embryonic/larval anterior spiracle

, genital disc | presumptive

, dorsal metathoracic disc

, ventral thoracic disc | presumptive

" "lethal,recessive,neurophysiology defective,female sterile,visible,dominant,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,somatic clone,heat sensitive,lethal - all die during pupal stage" "rhabdomere R7,embryonic/larval hemocyte | third instar larval stage,eye,macrochaeta & scutum-537.4,microchaeta & scutum-537.4,wing,chordotonal organ,lateral,imaginal disc,embryonic/larval tracheal system,ventral thoracic disc,somatic clone,embryonic/larval dorsal branch 1,embryonic/larval dorsal branch 2,embryonic/larval dorsal branch 3,embryonic/larval dorsal branch 4,embryonic/larval dorsal branch 5,embryonic/larval dorsal branch 6,embryonic/larval dorsal branch 7,embryonic/larval dorsal branch 8,embryonic/larval dorsal branch 9,embryonic/larval dorsal branch 10,embryonic/larval dorsal trunk,secondary pigment cell,tertiary pigment cell,histoblast,testis,macrochaeta,chaeta,adult thorax,thecogen cell,external sensory organ,tergite,sternite,lateral transverse muscle,muscle fiber,germinal proliferation center hub,hub cell,ommatidium,interommatidial bristle,scutellar bristle & trichogen cell455.2,scutellar bristle & tormogen cell455.2,tracheal system,leg,leg sensillum,leg & trichome | somatic clone,embryonic/larval salivary gland | embryonic stage,tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,scutellar bristle,pigment cell,supernumerary" FBgn0259685 crb crumbs http://flybase.net/reports/FBgn0259685.html "FBgn0086905, FBgn0000368, FBgn0024518, FBgn0028125, FBgn0060827, FBgn0010919, FBgn0044351" protein_coding_gene "0005509=calcium ion binding, 0005080=protein kinase C binding, 0030507=spectrin binding" "0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0045198=establishment of epithelial cell apical/basal polarity, 0007431=salivary gland development, 0050821=protein stabilization, 0045218=zonula adherens maintenance, 0046621=negative regulation of organ growth, 0035330=regulation of hippo signaling, 0007399=nervous system development, 0034332=adherens junction organization, 0032880=regulation of protein localization, 0061541=rhabdomere morphogenesis, 0007443=Malpighian tubule morphogenesis, 0007163=establishment or maintenance of cell polarity, 0033157=regulation of intracellular protein transport, 0035088=establishment or maintenance of apical/basal cell polarity, 0001738=morphogenesis of a polarized epithelium, 0045746=negative regulation of Notch signaling pathway, 0007424=open tracheal system development, 0045494=photoreceptor cell maintenance, 0035002=liquid clearance, open tracheal system, 0016332=establishment or maintenance of polarity of embryonic epithelium, 0045186=zonula adherens assembly, 0002009=morphogenesis of an epithelium, 0061024=membrane organization, 0035090=maintenance of apical/basal cell polarity, 0016334=establishment or maintenance of polarity of follicular epithelium, 0048477=oogenesis, 0035239=tube morphogenesis, 0032435=negative regulation of proteasomal ubiquitin-dependent protein catabolic process, 0007043=cell-cell junction assembly, 0061336=cell morphogenesis involved in Malpighian tubule morphogenesis, 0007435=salivary gland morphogenesis, 0042051=compound eye photoreceptor development, 0045570=regulation of imaginal disc growth, 0042327=positive regulation of phosphorylation, 0001745=compound eye morphogenesis, 0008104=protein localization, 0008284=positive regulation of cell proliferation, 0046664=dorsal closure, amnioserosa morphology change, 0042052=rhabdomere development" "0005913=cell-cell adherens junction, 0016327=apicolateral plasma membrane, 0035003=subapical complex, 0005918=septate junction, 0016021=integral component of membrane, 0016028=rhabdomere, 0005886=plasma membrane, 0016324=apical plasma membrane" "CG6383, Crumbs, Crb, Crbs, l(3)07207, l(3)S058104, 1384/04, CRB, l(3)S050920, DmCrb, far, fat rhabdomeres, CT19912, 0509/20, crumb, l(3)j1B5, fat rhabdomere, lethal (3) 07207" "IPR001881=EGF-like calcium-binding domain, IPR013032=EGF-like, conserved site, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR001791=Laminin G domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR018097=EGF-like calcium-binding, conserved site, IPR000742=EGF-like domain" CG6383 16-Dec-15 2015_12 "ENSDARG00000060081(crb2l),ENSDARG00000060106(crb2),ENSDARG00000062245(crb1)" WBGene00000792(crb-1) ENSXETG00000009953(CRB1) ENSMUSG00000063681(Crb1) ENSG00000134376(CRB1) " embryonic stage -- adult stage , embryonic stage | late , embryonic stage " " adult salivary gland primordium

posterior & dorsal , embryonic/larval hindgut

" " embryonic stage | late , larval stage | third instar , adult stage | male , embryonic stage , embryonic stage | stage 8-11 , pupal stage , embryonic stage | stage 16 , adult stage && oogenesis stage " " adult salivary gland primordium

, embryonic/larval garland cell

, ejaculatory bulb

, ectoderm

, optic lobe

, neuroblast

, photoreceptor cell stalk | apical

, hindgut

, embryonic/larval salivary gland

, external sensory organ

, embryonic/larval foregut

, ejaculatory duct

, embryonic peripheral nervous system

, testicular duct

, peripodial epithelium

, stomodeum

, salivary gland imaginal ring

, posterior embryonic/larval midgut

, embryonic/larval hindgut

, Malpighian tubule

, epithelial cell

, seminal vesicle

, follicle cell

, embryonic/larval trachea

, imaginal disc

, stomatogastric nervous system

, endoderm

, chordotonal organ

, male accessory gland

" FBgn0025185 az2 az2 http://flybase.net/reports/FBgn0025185.html FBgn0022958 protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0008270=zinc ion binding, 0046872=metal ion binding" "0006355=regulation of transcription, DNA-templated" "Zinc finger protein 43C, zf43C, CG1605" "IPR006578=MADF domain, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2" CG1605 16-Dec-15 2015_12 WBGene00003380(mnm-2) " adult stage && oogenesis stage , adult stage | female && oogenesis stage | stage =S10B " " nurse cell

, ovary

, oocyte

" FBgn0262445 mir-133 mir-133 stem loop http://flybase.net/reports/FBgn0262445.html "FBgn0067340, FBgn0262304" miRNA_gene "CR33574, miR-133, dme-mir-133, mir-133, dme-miR-133, CR43011" CR43011 16-Dec-15 2015_12 " embryonic stage , pupal stage " "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye,wing,wing vein" FBgn0010389 htl heartless http://flybase.net/reports/FBgn0010389.html "FBgn0004599, FBgn0022791" protein_coding_gene "0005007=fibroblast growth factor-activated receptor activity, 0004713=protein tyrosine kinase activity, 0005524=ATP binding" "0048542=lymph gland development, 0007522=visceral muscle development, 0006468=protein phosphorylation, 0061320=pericardial nephrocyte differentiation, 0050829=defense response to Gram-negative bacterium, 0008543=fibroblast growth factor receptor signaling pathway, 0001710=mesodermal cell fate commitment, 0045089=positive regulation of innate immune response, 0007517=muscle organ development, 0008347=glial cell migration, 0010001=glial cell differentiation, 0008284=positive regulation of cell proliferation, 0007419=ventral cord development, 0007492=endoderm development, 0007506=gonadal mesoderm development, 0007523=larval visceral muscle development, 0007500=mesodermal cell fate determination, 0008406=gonad development, 0008078=mesodermal cell migration, 0007507=heart development, 0008360=regulation of cell shape, 0021782=glial cell development, 0007280=pole cell migration, 0007417=central nervous system development, 0007369=gastrulation, 0007509=mesoderm migration involved in gastrulation, 0048747=muscle fiber development, 0016477=cell migration, 0010002=cardioblast differentiation, 0007525=somatic muscle development, 0008354=germ cell migration, 0007498=mesoderm development, 0007493=endodermal cell fate determination, 0007431=salivary gland development" "0016021=integral component of membrane, 0005886=plasma membrane" "HD-38, HTL/FGFR1, heartless, DTRK(FR1), DFGF-R2, FGFR, Heartless, Fibroblast growth factor receptor 1, dtk1, DFR-1, FGF-R2, Fibroblast growth factor receptor, i150, CT22273, FR1, Htl, i79, FGFR2, Dfr-1, Fr1, Dfr1, j372, fibroblast growth factor receptor, CT39172, EMS2, i100, FGF receptor, DPR3, Dtk1, DFGF-R1, DFR1, DmHD-38, DFR1/DFGF-R2, CG7223, Tk1" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR013783=Immunoglobulin-like fold, IPR008266=Tyrosine-protein kinase, active site, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR016248=Fibroblast growth factor receptor family, IPR000719=Protein kinase domain, IPR007110=Immunoglobulin-like domain, IPR017441=Protein kinase, ATP binding site, IPR013098=Immunoglobulin I-set, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG7223 16-Dec-15 2015_12 "ENSDARG00000004782(fgfr3),ENSDARG00000069105(fgfr4),ENSDARG00000011027(fgfr1a),ENSDARG00000011190,ENSDARG00000058115" WBGene00001184(egl-15) "ENSXETG00000002396(),ENSXETG00000016775(fgfr1),ENSXETG00000015592(FGFR2),ENSXETG00000007231(fgfr4)" "ENSMUSG00000030849(Fgfr2),ENSMUSG00000031565(Fgfr1),ENSMUSG00000054252(Fgfr3),ENSMUSG00000005320(Fgfr4)" "ENSG00000066468(FGFR2),ENSG00000077782(FGFR1),ENSG00000160867(FGFR4),ENSG00000068078(FGFR3)" " embryonic stage | stage 12-16 , embryonic stage | stage 12-13 , embryonic stage | stage 11-12 , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 9 , embryonic stage | stage 5-9 " " central nervous system

, embryonic/larval hindgut

, myoblast &&of larval muscle system

, abdominal 1--7 lateral transverse muscle 3

, abdominal 1--7 ventral acute muscle 2

, abdominal 1--7 ventral acute muscle 1

, longitudinal connective

, embryonic/larval foregut

, abdominal 1--7 lateral transverse muscle 2

, abdominal 2--7 ventral transverse muscle 1

, somatic mesoderm

, abdominal 1--7 lateral transverse muscle 1

, mesoderm

, head mesoderm

" " larval stage | third instar , embryonic stage | stage 11-12 " " dorsal mesothoracic disc && adepithelial cell | restricted

, mesoderm

" "lethal,recessive,wild-type,cell migration defective,increased cell death,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,increased cell number,viable,visible" "presumptive embryonic salivary gland,visceral mesoderm,muscle founder cell,myoblast,muscle fiber,glial cell,embryonic/larval dorsal vessel,embryonic visceral muscle,embryonic/larval somatic muscle,interface glial cell,hindgut visceral muscle primordium,hindgut visceral muscle fiber,mesoderm,embryonic/larval muscle system,dorsal,heart primordium,axon & ocellus sensory structureBx-MS1096, Mz1277, twi.PB, htlUAS.cMa,axon & mechanosensory neuron & adult headBx-MS1096, Mz1277, twi.PB, htlUAS.cMa,somatic mesoderm,axon & ocellus sensory structure-537.4, htlDN.UAS.cMb,axon & mechanosensory neuron & adult head-537.4, htlDN.UAS.cMb,cardiogenic mesoderm,lymph gland primordium,embryonic pericardial cell,cardioblast,pericardial cell,embryonic/larval pericardial cell,embryonic/larval cardial cell,ventral nerve cord,ventral furrow,somatic clone,corpus cardiacum primordium,longitudinal visceral muscle primordium,longitudinal visceral muscle fiber,dorsal oblique muscle,ventral longitudinal muscle,ventral oblique muscle,lateral transverse muscle,dorsal transverse muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle 1,abdominal 1 dorsal acute muscle 1,abdominal 2 dorsal acute muscle 1,abdominal 3 dorsal acute muscle 1,abdominal 4 dorsal acute muscle 1,abdominal 5 dorsal acute muscle 1,abdominal 6 dorsal acute muscle 1,abdominal 7 dorsal acute muscle 1,embryonic myoblast,germline cell,gonadal sheath proper primordium,embryonic somatic muscle,axon & ocellus sensory structure-537.4,axon & mechanosensory neuron & adult head-537.4,axon & ocellus sensory structure-537.4, htlAB42,axon & mechanosensory neuron & adult head-537.4, htlAB42,subretinal glial cell,somatic clone | third instar larval stage,ventral nerve cord | embryonic stage,embryonic/larval dorsal vessel | embryonic stage,ventral,axon & ocellus sensory structureBx-MS1096, Mz1277, twi.PB, htlYY262/htlAB42,axon & mechanosensory neuron & adult headBx-MS1096, Mz1277, twi.PB, htlYY262/htlAB42,supernumerary,tarsal levator muscle,wing vein L5,wing vein,ectopic,embryonic cardioblast,trichogen cell" FBgn0266751 CR45224 http://flybase.net/reports/FBgn0266751.html non_protein_coding_gene CR45224 16-Dec-15 2015_12 FBgn0016991 ms(2)1336A ms(2)1336A http://flybase.net/reports/FBgn0016991.html gene ms(3)1336A 16-Dec-15 2015_12 spermatid FBgn0044400 Scim27 Sensitized chromosome inheritance modifier 27 http://flybase.net/reports/FBgn0044400.html gene 0016321=female meiosis chromosome segregation 16-Dec-15 2015_12 "meiotic cell cycle defective,dominant" FBgn0004907 14-3-3ë¦ 14-3-3ë¦ http://flybase.net/reports/FBgn0004907.html "FBgn0010635, FBgn0019723, FBgn0023038, FBgn0046306, FBgn0064146" protein_coding_gene "0019904=protein domain specific binding, 0008426=protein kinase C inhibitor activity, 0005515=protein binding, 0046982=protein heterodimerization activity, 0042803=protein homodimerization activity, 0016483=tryptophan hydroxylase activator activity" "0046579=positive regulation of Ras protein signal transduction, 0007059=chromosome segregation, 0040040=thermosensory behavior, 0008103=oocyte microtubule cytoskeleton polarization, 0070374=positive regulation of ERK1 and ERK2 cascade, 0007294=germarium-derived oocyte fate determination, 0006588=activation of tryptophan 5-monooxygenase activity, 0008283=cell proliferation, 0050821=protein stabilization, 0008355=olfactory learning, 0006457=protein folding, 0001751=compound eye photoreceptor cell differentiation, 0045448=mitotic cell cycle, embryonic, 0007265=Ras protein signal transduction, 0007611=learning or memory" "0005634=nucleus, 0005737=cytoplasm, 0005875=microtubule associated complex, 0031965=nuclear membrane, 0005886=plasma membrane, 0045172=germline ring canal" "l(2)46CFe, leonardo, Leonardo-13-3-3, leo, K, 14-3-3leo, LEONARDO, 14-3-3zeta, Complementation group K, 549, unnamed, 4-3-3 zeta, 14-3-3 zeta, D14-3-3zeta, 2G1, 14-3-3-zeta, LEO, l(2)46Ee, d14-3-3zeta, PAR5, l(2)07103, 14-3-3-Leo, leonardo 14-3-3, par-5, Leonardo, D14 3 3 protein, BEST:GH05075, Leo, 5.11, D14-3-3, CG17870, PAR-5, 14-3-3ZETA, Par-5, 14-3-3" "IPR023409=14-3-3 protein, conserved site, IPR000308=14-3-3 protein, IPR023410=14-3-3 domain" CG17870 16-Dec-15 2015_12 "ENSDARG00000013078(ywhaba),ENSDARG00000015382,ENSDARG00000040287(ywhabl),ENSDARG00000023323(ywhaqb),ENSDARG00000042539(ywhaqa)" "WBGene00001502(ftt-2),WBGene00003920(par-5)" ENSXETG00000026459(ywhaz) "ENSMUSG00000022285(Ywhaz),ENSMUSG00000018326(Ywhab)" "ENSG00000164924(YWHAZ),ENSG00000166913(YWHAB)" " adult stage , embryonic stage , larval stage | third instar , adult stage && oogenesis stage , larval stage " " retina

, adult brain

, ventral nerve cord

, lamina

, adult head

, subesophageal ganglion

, embryonic central nervous system

, optic lobe

, eye disc

, mushroom body

, nurse cell

, thoracico-abdominal ganglion

, oocyte

, antennal lobe

, morphogenetic furrow | posterior to

, larval central nervous system

" " adult stage && oogenesis stage , adult stage , larval stage | third instar , embryonic stage | 16-18hr , embryonic stage | late , embryonic stage | 20 hr , embryonic stage | stage 17 , larval stage " " oocyte

, thoracico-abdominal ganglion

, nurse cell

, ring neuron

, eye disc

, cell body

, synapse

, ellipsoid body

, bouton

, neuromuscular junction

, neuron

, larval muscle system

, morphogenetic furrow | posterior to

, mushroom body

, antennal lobe

" "memory defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,learning defective,neurophysiology defective,mitotic cell cycle defective,maternal effect,fertile,wild-type" "eye photoreceptor cell,somatic clone,embryonic/first instar larval cuticle,germline clone,denticle belt,syncytial blastoderm embryo,mitotic cell cycle | maternal effect,follicle cell,border follicle cell,photoreceptor cell,embryonic epidermis,lateral,dorsal,embryo,posterior,filzkorper" DRSC05028 I -2.132383757 -1.133882546 0.502046612 0.1426068 -0.137782331 -0.462856079 FBgn0259212 cno canoe http://flybase.net/reports/FBgn0259212.html "FBgn0000340, FBgn0000465, FBgn0005637, FBgn0046384, FBgn0051537" protein_coding_gene "0003779=actin binding, 0005515=protein binding, 0019904=protein domain specific binding, 0017016=Ras GTPase binding" "0007391=dorsal closure, 0007394=dorsal closure, elongation of leading edge cells, 0007265=Ras protein signal transduction, 0016330=second mitotic wave involved in compound eye morphogenesis, 0007219=Notch signaling pathway, 0046328=regulation of JNK cascade, 0014009=glial cell proliferation, 0048730=epidermis morphogenesis, 0007254=JNK cascade, 0016318=ommatidial rotation, 0007163=establishment or maintenance of cell polarity, 0000132=establishment of mitotic spindle orientation, 0032880=regulation of protein localization, 0048749=compound eye development, 0048598=embryonic morphogenesis" "0005926=connecting hemi-adherens junction, 0005915=zonula adherens, 0005938=cell cortex, 0005912=adherens junction" "cno?, anon-WO0172774.47, lip, Canoe, dorsal holes A, Afadin, AF-6, CG42312, canoe, misty, CG31537, Cno, CG2534, afadin, lips, dlhA, EC3-10, mis" "IPR001478=PDZ domain, IPR008984=SMAD/FHA domain, IPR029071=Ubiquitin-related domain, IPR000159=Ras-associating (RA) domain, IPR002710=Dilute domain, IPR000253=Forkhead-associated (FHA) domain" CG42312 16-Dec-15 2015_12 ENSDARG00000029472(mllt4) WBGene00021009(afd-1) ENSG00000130396(MLLT4) " embryonic stage -- adult stage , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | stage 13 , embryonic stage | stage 7-10 , embryonic stage , larval stage " " organism | restricted

,

ubiquitous , ectoderm

, embryonic/larval proventriculus

, posterior embryonic/larval midgut

, epidermis

, organism | striped

, eye-antennal disc

" FBgn0004860 ph-d polyhomeotic distal http://flybase.net/reports/FBgn0004860.html "FBgn0003077, FBgn0026824" protein_coding_gene "0008270=zinc ion binding, 0051087=chaperone binding, 0001047=core promoter binding, 0003682=chromatin binding" "0006342=chromatin silencing, 0045892=negative regulation of transcription, DNA-templated, 0035186=syncytial blastoderm mitotic cell cycle" "0005730=nucleolus, 0000785=chromatin, 0035102=PRC1 complex, 0005634=nucleus" "phd, PH, ph[d], PHD, Ph-d, phm, PH-d, ph, CG3895, ph-D, EG:BACN25G24.3, polyhomeotic-distal, Polyhomeotic-distal, Ph, polyhomeotic, polyhomeotic proximal, DROZFP, Polyhomeotic, PhD, ph[D]" "IPR001660=Sterile alpha motif domain, IPR012313=Zinc finger, FCS-type, IPR013761=Sterile alpha motif/pointed domain" CG3895 16-Dec-15 2015_12 "ENSDARG00000013224(zgc:56685),ENSDARG00000056695(phc2)" ENSXETG00000009212(PHC3) ENSMUSG00000040669(Phc1) "ENSG00000111752(PHC1),ENSG00000173889(PHC3),ENSG00000179899,ENSG00000134686(PHC2)" " adult stage && oogenesis stage | stage S1-10 , larval stage | third instar , embryonic stage | blastoderm , embryonic stage | stage >=12 , embryonic stage | stage 8-11 , embryonic stage , adult stage && oogenesis stage , embryonic stage -- adult stage " " follicle cell

, ventral thoracic disc

, nurse cell

,

50-80% egg length , embryonic central nervous system

, eye-antennal disc

, germ band

, parasegment | restricted

, dorsal mesothoracic disc

, germarium

, dorsal metathoracic disc

,

ubiquitous " " embryonic stage , larval stage | third instar , embryonic stage | late " " cell body

,

ubiquitous , dorsal mesothoracic disc

, embryonic peripheral nervous system

, ventral thoracic disc

, dorsal metathoracic disc

, sensillum campaniformium

, embryonic central nervous system

, eye-antennal disc

" "viable,wild-type,lethal,recessive,heat sensitive,visible,eye color defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "mesothoracic leg,metathoracic leg,wing,posterior compartment,abdominal segment 1,abdominal segment 4,humerus,humeral bristle,anterior compartment,heat sensitive,adult abdominal segment 1,adult abdominal segment 4,sex comb,eye,wing margin bristle,abdominal sternite 6,female,abdominal sternite 7,genitalia,adult thoracic segment,adult abdominal segment,cuticle,head,nuclear chromosome,ventral,cuticle & denticle,epidermis,cell autonomous,somatic clone" DRSC23191 K 1.910230444 1.155417935 FBgn0003249 Rh3 Rhodopsin 3 http://flybase.net/reports/FBgn0003249.html protein_coding_gene "0008020=G-protein coupled photoreceptor activity, 0004930=G-protein coupled receptor activity" "0009589=detection of UV, 0007601=visual perception, 0007602=phototransduction, 0016039=absorption of UV light, 0007604=phototransduction, UV, 0007186=G-protein coupled receptor signaling pathway" 0016021=integral component of membrane "RH3, Rhodopsin3, Rh, rhodopsin, DMELRH3, Rhodopsin, FBgn0003249, unnamed, rh3, CG10888, Dm Rh3" "IPR000276=G protein-coupled receptor, rhodopsin-like, IPR027430=Visual pigments (opsins) retinal binding site, IPR000856=Opsin RH3/RH4, IPR017452=GPCR, rhodopsin-like, 7TM" CG10888 16-Dec-15 2015_12 ENSXETG00000019216(OPN4) " larval stage , adult stage , pupal stage | late " " Bolwig's organ

, eye

, photoreceptor cell R7

, adult head

" adult stage " photoreceptor cell R1--6

{ 0 ninaE- } , photoreceptor cell R1..6

{ 0 ninaA* } , photoreceptor cell R1--6

, photoreceptor cell R8

, photoreceptor cell R7 | presumptive

" "neurophysiology defective,visual behavior defective,viable" "ommatidium,eye photoreceptor cell" FBgn0013811 Dhc62B Dynein heavy chain at 62B http://flybase.net/reports/FBgn0013811.html FBgn0035269 protein_coding_gene "0003777=microtubule motor activity, 0003774=motor activity, 0042623=ATPase activity, coupled" "2001019=positive regulation of retrograde axon cargo transport, 0007018=microtubule-based movement" "0005875=microtubule associated complex, 0005858=axonemal dynein complex" "Dhc, Dynein Heavy chain 62B, dhc, DHC, CG15804, unnamed, dynein-related heavy chain polypeptide, CG18613" "IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR024317=Dynein heavy chain, P-loop containing D4 domain, IPR004273=Dynein heavy chain domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013602=Dynein heavy chain, domain-2" CG15804 16-Dec-15 2015_12 " adult stage , adult stage | male , embryonic stage , adult stage | female " testis

"viable,fertile,lethal" FBgn0004580 Cbp53E Calbindin 53E http://flybase.net/reports/FBgn0004580.html protein_coding_gene 0005509=calcium ion binding "0006874=cellular calcium ion homeostasis, 1903035=negative regulation of response to wounding" "cbn, Calbindin 32, CG6702, unnamed, Dcp, Dcbp, cbp53E, Calb, DCBP, calbindin, calbindin-32, CALB2, CALB2/calretinin, Calbindin, Calretinin, Cbp33" "IPR011992=EF-hand domain pair, IPR002048=EF-hand domain, IPR018247=EF-Hand 1, calcium-binding site" CG6702 16-Dec-15 2015_12 ENSDARG00000058732(zgc:100843) "ENSXETG00000015886(CALB2),ENSXETG00000014607(CALB1)" "ENSMUSG00000003657(Calb2),ENSMUSG00000028222(Calb1)" "ENSG00000172137(CALB2),ENSG00000104327(CALB1)" " adult stage , larval stage | third instar , embryonic stage | >12hr , embryonic stage | late " " ocellar nerve

, medulla layer M2

, antenna | restricted

, larval central nervous system | restricted

, adult central nervous system

, neuron

, embryonic central nervous system | restricted

, embryonic peripheral nervous system | restricted

, lamina

, thoracico-abdominal ganglion

, direct flight muscle

, ventral midline

, adult brain | restricted

" " embryonic stage | >12hr , adult stage , embryonic stage | > 12hr , larval stage | third instar , embryonic stage | late " " embryonic peripheral nervous system | restricted

, lamina

, embryonic central nervous system | restricted

, neuron

, larval central nervous system | restricted

, ventral midline

, adult brain | restricted

, adult central nervous system

, antenna

, thoracico-abdominal ganglion

, direct flight muscle

, medulla layer M2

" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0004837 Su(H) Suppressor of Hairless http://flybase.net/reports/FBgn0004837.html "FBgn0003566, FBgn0004467, FBgn0021969, FBgn0022068, FBgn0063792" protein_coding_gene "0000978=RNA polymerase II core promoter proximal region sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003677=DNA binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0005515=protein binding" "1900087=positive regulation of G1/S transition of mitotic cell cycle, 0045893=positive regulation of transcription, DNA-templated, 0007616=long-term memory, 0016360=sensory organ precursor cell fate determination, 0007219=Notch signaling pathway, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0030097=hemopoiesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0001709=cell fate determination, 0042688=crystal cell differentiation, 0008586=imaginal disc-derived wing vein morphogenesis, 0048190=wing disc dorsal/ventral pattern formation, 0007252=I-kappaB phosphorylation, 0046331=lateral inhibition, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0008356=asymmetric cell division, 0042683=negative regulation of compound eye cone cell fate specification, 0045892=negative regulation of transcription, DNA-templated" "0005700=polytene chromosome, 0005737=cytoplasm, 0005634=nucleus, 0017053=transcriptional repressor complex, 0043234=protein complex" "CSL, SU(H), lethal group D, su(H), E(H), SuH, Su_H, FTZ-F2, Suppressor-of-Hairless, oss, Supressor of Hairless, dRBP-J[[Kappa]], suppressor of hairless, l(1)br7, Su(h), suppressor of Hairless, dRBP-JK, CBF1, l(2)k07904, RBJK_DROME, l(2)br7, lethal 7 in the black-reduced region, SUH, RBP-J[[Kappa]], RBP-Jkappa, suppressor-of-hairless, CG3497, Suppressor of hairless, dRBP-Jk, anon-WO0257455.3, BG:DS00929.10, C, br7, D, l(2)35Bh, transcription unit C, RBP-J kappa" "IPR013783=Immunoglobulin-like fold, IPR015351=LAG1, DNA binding, IPR014756=Immunoglobulin E-set, IPR015350=Beta-trefoil DNA-binding domain, IPR008967=p53-like transcription factor, DNA-binding" CG3497 16-Dec-15 2015_12 "ENSDARG00000003398(rbpja),ENSDARG00000052091(rbpjb)" WBGene00002245(lag-1) ENSXETG00000000935(RBPJ) "ENSMUSG00000079575,ENSMUSG00000039191(Rbpj)" ENSG00000168214(RBPJ) " embryonic stage | early , adult stage | female , adult stage | male , pupal stage | 24hr , embryonic stage , embryonic stage | stage >=11 , embryonic stage -- adult stage , larval stage | third instar , pupal stage | 16-24 hr , pupal stage | 16-24hr " " tormogen cell

, external sensory organ

, trichogen cell

, eye-antennal disc

, epidermis

, ventral thoracic disc

, dorsal mesothoracic disc

, adult muscle system | presumptive

" " larval stage | third instar , pupal stage , embryonic stage " " proneural cluster

, socket

, external sensory organ precursor cell IIb

, external sensory organ

, dorsal mesothoracic disc

, external sensory organ precursor cell IIa

, socket &&of interommatidial bristle

, embryonic peripheral nervous system | restricted

, sensory mother cell

" "hyperplasia,visible,neuroanatomy defective,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,neurogenic phenotype,rescuable maternal effect,somatic clone,wild-type,memory defective,increased cell death,mitotic cell cycle defective,cell autonomous,dominant,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" "wing,wing margin,wing disc | third instar larval stage,macrochaeta,microchaeta,eye,apterous-expressing neuron of the lateral cluster of the thorax,chaeta,adult thorax,imaginal disc,wing vein,trichogen cell,ommatidium,wing disc,proneural cluster,proventriculus inner layer primordium,proventriculus intermediate layer primordium,proventriculus outer layer primordium,embryonic proventriculus,keyhole structure,embryonic/first instar larval cuticle,germline clone,ventral,embryonic/first instar larval cuticle & embryonic head | germ-line clone,neuroblast,central nervous system,peripheral nervous system,sensory mother cell,ectopic,dorsal double row,ventral double row,proneural cluster & dorsal mesothoracic disc,wing vein L3,femur,distal,somatic clone,tibia,proximal,joint,leg,anterior compartment,eye-antennal disc,socket,tormogen cell,crystal cell,embryonic/larval lymph gland,haltere,dorsal mesothoracic disc & neuron,eye disc,follicle cell,egg chamber,germinal vesicle | somatic clone,photoreceptor cell R8 & eye disc | somatic clone,photoreceptor cell R8 & eye disc | ectopic | somatic clone,neuron & eye | supernumerary | somatic clone,neuron & eye | somatic clone,adult midgut,germarium region 1,cell autonomous,larval outer optic anlage,intestinal stem cell,supernumerary,type II neuroblast,adult midgut epithelium,mesothoracic tergum & sensory organ cell & pupa | somatic clone,sensory organ cell,unguis,plasmatocyte,eye disc & neuron | somatic clone | cell autonomous,photoreceptor cell R8,neuron,dMP2 neuron,vMP2 neuron,RP2sib neuron,RP2 motor neuron,Usib neuron,U neuron,embryonic/larval somatic muscle,embryonic epidermis,photoreceptor cell & axon & larva,photoreceptor cell,macrochaeta & leg,macrochaeta & adult abdomen,mesothoracic tergum,medial,anterior crossvein,wing margin bristle,visceral mesoderm,midline glial cell,medulla,pericardial cell,A1-7 dorsal acute muscle 1,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle 1,embryonic hindgut,embryonic large intestine,follicle stem cell,dorsal cluster neuron" FBgn0004895 fd64A forkhead domain 64A http://flybase.net/reports/FBgn0004895.html protein_coding_gene "0008301=DNA binding, bending, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003690=double-stranded DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding" "0009953=dorsal/ventral pattern formation, 0009792=embryo development ending in birth or egg hatching, 0045665=negative regulation of neuron differentiation, 0007346=regulation of mitotic cell cycle, 0002052=positive regulation of neuroblast proliferation, 0007380=specification of segmental identity, head, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0009888=tissue development, 0048665=neuron fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0016199=axon midline choice point recognition, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0035058=nonmotile primary cilium assembly, 0045787=positive regulation of cell cycle" "0005667=transcription factor complex, 0005634=nucleus" "FoxL1, FD2, fd2, Dmfd2, CG1132" "IPR001766=Fork head domain, IPR018122=Fork head domain conserved site1, IPR011991=Winged helix-turn-helix DNA-binding domain" CG1132 16-Dec-15 2015_12 "ENSDARG00000070716,ENSDARG00000069715(foxi2),ENSDARG00000019659(foxi1),ENSDARG00000009550(foxi3b),ENSDARG00000055926(foxi3a)" "ENSXETG00000001668(),ENSXETG00000001667(TGas140e03.1)" " embryonic stage | cellular blastoderm , embryonic stage " mesoderm

viable DRSC08717 E 0.973917967 -0.805484497 1.792386806 0.153550027 -0.768781966 0.555887593 FBgn0010194 Wnt5 Wnt oncogene analog 5 http://flybase.net/reports/FBgn0010194.html "FBgn0004361, FBgn0066822" protein_coding_gene "0005102=receptor binding, 0005110=frizzled-2 binding" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0045773=positive regulation of axon extension, 0009952=anterior/posterior pattern specification, 0016055=Wnt signaling pathway, 0016204=determination of muscle attachment site, 0009950=dorsal/ventral axis specification, 0048675=axon extension, 0070983=dendrite guidance, 0007411=axon guidance, 0060541=respiratory system development, 0060070=canonical Wnt signaling pathway, 0050919=negative chemotaxis, 0007435=salivary gland morphogenesis, 1902669=positive regulation of axon guidance, 0033564=anterior/posterior axon guidance" "0005576=extracellular region, 0005615=extracellular space, 0030425=dendrite, 0005886=plasma membrane" "Dm DWnt3/5, DWnt-5, DWnt-3, Dwnt5, wnt3, DWnt5, Wnt-3, Dwnt-5, DWnt3, Dwnt-3, CG6407, anon-WO03040301.228, wnt5, Wnt3/5, DWnt3/5, wnt-oncogene-analog-3, Wnt, Dm-3, Wnt3, DWnt-3/5, WNT5" "IPR018161=Wnt protein, conserved site, IPR005817=Wnt" CG6407 16-Dec-15 2015_12 "ENSG00000134245(WNT2B),ENSG00000105989(WNT2),ENSG00000114251(WNT5A),ENSG00000111186(WNT5B)" " embryonic stage | stage 10-11 , embryonic stage | stage 9-11 , embryonic stage | stage 11 , embryonic stage | gastrula , embryonic stage | stage 14-16 , embryonic stage , embryonic stage | cellular blastoderm , embryonic stage -- adult stage , embryonic stage | stage >11 , embryonic stage | stage 6-15 " " antennal segment

, antennal lobe

{ - Ba* } , maxillary lobe

, ventral metathoracic disc primordium

, ventral furrow | presumptive

, labral segment

{ - Ba* } , embryonic central nervous system

, ventral nerve cord

, ventral mesothoracic disc primordium

, antennal lobe

, ventral thoracic disc

,

20-80% egg length , ventral prothoracic disc primordium

, labial segment

, neuron &&of embryonic central nervous system | primordium

, maxillary lobe

{ - Ba* } , ventral neurectoderm

{ - Ba* } , embryonic brain

, mesoderm

, labial segment

{ - Ba* } , labral segment

" " embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 12 , embryonic stage | stage 13 " " labial segment

, ventral thoracic disc primordium

, labral segment

, embryonic brain

, maxillary segment

, neuromere

, antennal segment

, ventral nerve cord

segmentally repeated " "viable,fertile,uncoordinated,neuroanatomy defective,lethal,partially,recessive,visible,partially lethal - majority die,some die during pupal stage" "anterior commissure,presumptive embryonic salivary gland,antennal lobe,glomerulus,commissure,lateral longitudinal fascicle,intermediate longitudinal fascicle,axon & dorsal cluster neuron,fascicle,presumptive embryonic/larval central nervous system,MP1 neuron,MP1 tract,vMP2 tract,lateral transverse muscle,ventral nerve cord,trichogen cell,mesothoracic tergum" FBgn0261954 east enhanced adult sensory threshold http://flybase.net/reports/FBgn0261954.html "FBgn0010110, FBgn0023544, FBgn0027331, FBgn0040135, FBgn0066823, FBgn0003642" protein_coding_gene "0010629=negative regulation of gene expression, 0090235=regulation of metaphase plate congression, 0016321=female meiosis chromosome segregation, 0000705=achiasmate meiosis I, 0007552=metamorphosis" "0005634=nucleus, 0005730=nucleolus, 0005700=polytene chromosome, 0005654=nucleoplasm, 0000228=nuclear chromosome" "l(1)G0500, suppressor of white-spotted, l(1)G0014, anon-WO03040301.224, EAST, EG:133E12.4, East, CG4399, su(w[sp]), enhanced adult salt tolerance" CG4399 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage , embryonic stage | stage 9-17 , embryonic stage | stage 10 " " morphogenetic furrow

, procephalic neurogenic region

, embryonic central nervous system | presumptive

, peripheral nervous system

, supraesophageal ganglion

, sense organ

, eye-antennal disc

, tracheal primordium

, ventral neurogenic region

" DRSC18770 IE -0.646637796 -3.224435343 -1.200404052 -2.450070507 -0.73851466 -1.205191997 FBgn0005597 yemG9.5 yema gene 9.5 http://flybase.net/reports/FBgn0005597.html FBgn0004042 gene "yT9.5, yG9.5, unnamed" 16-Dec-15 2015_12 " embryonic stage | early , larval stage | second instar , larval stage | third instar , larval stage--adult stage , larval stage | first instar , adult stage && oogenesis stage , embryonic stage | stage >=11 , embryonic stage | stage >=15 , pupal stage--adult stage , adult stage , embryonic stage -- adult stage , pupal stage " " neuroblast

, spermatocyte

, ganglion mother cell

, ovary

, embryonic brain

,

ubiquitous , nurse cell

, embryonic central nervous system | subset

, adult brain cortex

, optic lobe

, imaginal disc

, neuroblast | ventral

" FBgn0013342 nSyb neuronal Synaptobrevin http://flybase.net/reports/FBgn0013342.html protein_coding_gene "0005515=protein binding, 0000149=SNARE binding, 0005484=SNAP receptor activity" "0016081=synaptic vesicle docking, 0007269=neurotransmitter secretion, 0016192=vesicle-mediated transport, 0006906=vesicle fusion" "0043195=terminal bouton, 0031201=SNARE complex, 0008021=synaptic vesicle, 0048786=presynaptic active zone, 0016021=integral component of membrane, 0005886=plasma membrane" "nSYB, Synaptobrevin, nsyb, neural-synaptobrevin, Nsyb, VAMP3, NSYB, N-synaptobrevin, Syb62A, n-Synaptobrevin, neuronal Synaptobrevin, neuronal synaptogrevin, neuronal-Synaptobrevin, syb, N-SYB, n-syb, neuronal SYNAPTOBREVIN, Syb, SYB, N-Syb, synaptobrevin, Dn-syb, N-syb, CG17248, n-Syb, neuronal synaptobrevin, n-synaptobrevin, nSyb, neuronal-synaptobrevin, Synaptobrevin-62A" IPR001388=Synaptobrevin CG17248 16-Dec-15 2015_12 "ENSDARG00000031283(vamp1),ENSDARG00000023492(zgc:92912),ENSDARG00000070693" WBGene00004897(snb-1) "ENSXETG00000008255(VAMP1),ENSXETG00000009096(VAMP2)" "ENSMUSG00000020894(Vamp2),ENSMUSG00000030337(Vamp1)" "ENSG00000179036,ENSG00000139190(VAMP1)" " embryonic stage -- adult stage , adult stage , embryonic stage | stage >=13 " " photoreceptor cell

, thoracico-abdominal ganglion

, embryonic peripheral nervous system

, adult brain cortex

, embryonic central nervous system

, cell body &&of optic lobe

" " embryonic stage , larval stage " " ventral nerve cord

, segmental nerve

, bouton

, synapse

, synapse &&of neuromuscular junction

, neuromuscular junction

, intersegmental nerve

, ventral nerve cord commissure

, neuromuscular junction &&of abdominal 1 ventral longitudinal muscle 4

, neuromuscular junction &&of abdominal 1 ventral longitudinal muscle 3

" "uncoordinated,viable,hypoactive,recessive,neurophysiology defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,behavior defective" "synapse,neuromuscular junction,synaptic vesicle & eye photoreceptor cell | somatic clone" FBgn0010109 dpn deadpan http://flybase.net/reports/FBgn0010109.html FBgn0025271 protein_coding_gene "0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003677=DNA binding, 0046983=protein dimerization activity, 0003700=sequence-specific DNA binding transcription factor activity" "0007530=sex determination, 0007540=sex determination, establishment of X:A ratio, 0008344=adult locomotory behavior, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated, 0045840=positive regulation of mitotic nuclear division, 0002052=positive regulation of neuroblast proliferation, 0008345=larval locomotory behavior, 0048813=dendrite morphogenesis, 0007219=Notch signaling pathway, 0007549=dosage compensation" 0005634=nucleus "bHLHe50, anon-EST:fe1B12, 44C, Deadpan, anon-fast-evolving-1B12, DPN, Dpn, unnamed, CG8704" "IPR003650=Orange domain, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG8704 16-Dec-15 2015_12 "ENSDARG00000006514(her6),ENSDARG00000056438(her9)" "ENSXETG00000001769(TNeu056p12.2),ENSXETG00000016852(TNeu075p16.1)" ENSMUSG00000022528(Hes1) "ENSG00000114315(HES1),ENSG00000188290(HES4)" " larval stage , embryonic stage , embryonic stage | embryonic cycle 13 , embryonic stage&&larval stage " " sensory neuron imaginal disc

{ - da* } , neuroblast

, organism | pair rule

, external sensory organ

, central nervous system

, organism | gap

, peripheral nervous system

, neuron

{ $ AS-C- } , embryonic neuron

, ventral neurogenic region

" " embryonic stage | stage 8 , embryonic stage | embryonic cycle 13 , larval stage , embryonic stage&&larval stage , embryonic stage " " procephalic neurogenic region && Pcv7 neuroblast && Pcv9 neuroblast

, organism | pair rule

, organism | gap

, external sensory organ

, neuroblast

, embryonic antennal segment && ventral neurogenic region && neuroblast

, embryonic neuron

, central nervous system

, ventral neurogenic region

, peripheral nervous system

, sensory neuron imaginal disc

{ - da* } , neuron

{ $ AS-C- } " "flightless,neuroanatomy defective,size defective,lethal,recessive,polyphasic,behavior defective,increased cell number,cell lethal,germline clone,somatic clone,partially lethal - majority live,uncoordinated,visible" "type II neuroblast | third instar larval stage,adult brain,embryonic/larval optic lobe | third instar larval stage,type II neuroblast,embryonic/larval optic lobe,lamina,type I neuroblast,mushroom body neuroblast,macrochaeta,embryonic/larval neuroblast,secondary neuroblast,supernumerary,ganglion mother cell,somatic clone,wing" FBgn0267791 HnRNP-K Heterogeneous nuclear ribonucleoprotein K http://flybase.net/reports/FBgn0267791.html "FBgn0015238, FBgn0010589, FBgn0050153, FBgn0015907, FBgn0020651, FBgn0034524" protein_coding_gene "0003723=RNA binding, 0008134=transcription factor binding, 0003729=mRNA binding" "0008283=cell proliferation, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0007446=imaginal disc growth, 0035107=appendage morphogenesis, 0045165=cell fate commitment" "0030529=ribonucleoprotein complex, 0005737=cytoplasm, 0005634=nucleus, 0035062=omega speckle, 0000785=chromatin" "Q18, unnamed, Bancal, hnRNP K, hnRNP-A1L, Hrb57A, BL, Heterogeneous nuclear ribonucleoprotein K, Heterogeneous nuclear ribonucleoprotein at 57A, CG13425, bancal hnRNP, bancal, bl, l(2)k08305, dhnRNP K" "IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG13425 16-Dec-15 2015_12 "ENSDARG00000018914(hnrnpk),ENSDARG00000007034(hnrpkl)" YBR233W(PBP2) WBGene00017816(F26B1.2) ENSXETG00000011722(HNRNPK) "ENSMUSG00000021546(Hnrnpk),ENSMUSG00000063902" ENSG00000165119(HNRNPK) " embryonic stage | <=10 hr , larval stage | third instar , larval stage&&pupal stage , adult stage | female , embryonic stage " " larval stage | third instar , embryonic stage " " imaginal disc

,

ubiquitous " DRSC22734 IE -1.698907134 0.798972119 -1.247340001 -2.420729614 0.269161219 -1.091553385 FBgn0015380 drl derailed http://flybase.net/reports/FBgn0015380.html "FBgn0032764, FBgn0032765" protein_coding_gene "0005524=ATP binding, 0042803=protein homodimerization activity, 0046982=protein heterodimerization activity, 0004713=protein tyrosine kinase activity, 0019901=protein kinase binding, 0017147=Wnt-protein binding" "0007165=signal transduction, 0007411=axon guidance, 0007611=learning or memory, 0016204=determination of muscle attachment site, 0016203=muscle attachment, 0008355=olfactory learning, 0007482=haltere development, 0007613=memory, 0070983=dendrite guidance, 0006468=protein phosphorylation, 0030178=negative regulation of Wnt signaling pathway, 0016199=axon midline choice point recognition, 0007435=salivary gland morphogenesis" "0030424=axon, 0005886=plasma membrane, 0030425=dendrite, 0005887=integral component of plasma membrane, 0043235=receptor complex" "lin, CG17348, lio, Drl, DRL, derailed, Derailed, CG10758, unnamed, linotte, lio/drl, lionette" "IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR003306=WIF domain, IPR000719=Protein kinase domain, IPR008266=Tyrosine-protein kinase, active site, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain" CG17348 16-Dec-15 2015_12 ENSDARG00000007231(zgc:158381) WBGene00003007(lin-18) ENSXETG00000011818(RYK) ENSMUSG00000032547(Ryk) ENSG00000163785(RYK) " embryonic stage | 10-14 hr , embryonic stage " " abdominal 2--7 lateral transverse muscle 1

, interneuron

, abdominal 2--7 lateral transverse muscle 3

, abdominal 2--7 lateral transverse muscle 2

" " E | stage 11-15 , embryonic stage , larval stage | third instar , embryonic stage | 10-14 hr " " epidermis | restricted

, interneuron

, larval optic lobe

, abdominal 2--7 lateral transverse muscle 3

, abdominal 2--7 lateral transverse muscle 1

, larval brain | restricted

, abdominal 2--7 lateral transverse muscle 2

, anterior commissure

" "uncoordinated,viable,female fertile,male fertile,recessive,memory defective,neuroanatomy defective,lethal - all die before end of pupal stage,partially,some die during pupal stage,wild-type,behavior defective,neurophysiology defective,visible" "adult central complex,axon | embryonic stage,mushroom body alpha-lobe,mushroom body beta-lobe,fan-shaped body,adult mushroom body,perikaryon,adult brain,adult mushroom body beta'-lobe,ventral nerve cord commissure,longitudinal connective,lobe system of adult mushroom body,abdominal 1 lateral transverse muscle 1,abdominal 2 lateral transverse muscle 1,abdominal 3 lateral transverse muscle 1,abdominal 4 lateral transverse muscle 1,abdominal 5 lateral transverse muscle 1,abdominal 6 lateral transverse muscle 1,abdominal 7 lateral transverse muscle 1,abdominal 1 lateral transverse muscle 2,abdominal 2 lateral transverse muscle 2,abdominal 3 lateral transverse muscle 2,abdominal 4 lateral transverse muscle 2,abdominal 5 lateral transverse muscle 2,abdominal 6 lateral transverse muscle 2,abdominal 7 lateral transverse muscle 2,abdominal 1 lateral transverse muscle 3,abdominal 2 lateral transverse muscle 3,abdominal 3 lateral transverse muscle 3,abdominal 4 lateral transverse muscle 3,abdominal 5 lateral transverse muscle 3,abdominal 6 lateral transverse muscle 3,abdominal 7 lateral transverse muscle 3,mushroom body pedunculus,protocerebral bridge,optic lobe,embryonic/larval somatic muscle,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,anterior commissure,ventral nerve cord,presumptive embryonic salivary gland,antennal lobe,glomerulus,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1,olfactory receptor neuron,pupa,lateral transverse muscle,embryonic/larval brain,protocerebrum,dorsal,mushroom body gamma-lobe,ellipsoid body,ring neuron,presumptive embryonic/larval central nervous system,posterior commissure,interneuron,embryonic ventral nervous system,chaeta,supernumerary" FBgn0003448 sna snail http://flybase.net/reports/FBgn0003448.html FBgn0016654 protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0001106=RNA polymerase II transcription corepressor activity, 0046872=metal ion binding, 0070491=repressing transcription factor binding, 0000975=regulatory region DNA binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007375=anterior midgut invagination, 0007370=ventral furrow formation, 0007369=gastrulation, 0007499=ectoderm and mesoderm interaction, 0007517=muscle organ development, 0031065=positive regulation of histone deacetylation, 0048749=compound eye development, 0001710=mesodermal cell fate commitment, 0045893=positive regulation of transcription, DNA-templated, 0007443=Malpighian tubule morphogenesis, 0007501=mesodermal cell fate specification, 0009950=dorsal/ventral axis specification, 0007500=mesodermal cell fate determination, 0010629=negative regulation of gene expression, 0055059=asymmetric neuroblast division, 0007417=central nervous system development, 0048813=dendrite morphogenesis, 0010004=gastrulation involving germ band extension, 0034332=adherens junction organization, 0007498=mesoderm development, 0045892=negative regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0007450=dorsal/ventral pattern formation, imaginal disc" 0005634=nucleus "l35Db, l(2)br28, l(3)br28, sna, Sna, SNA, Snail, Scutoid, l(2)br29, l(2)35Db, br28, br29, sn, Sco, snail, CG3956, BG:DS01845.1" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR015880=Zinc finger, C2H2-like, IPR007087=Zinc finger, C2H2, IPR029795=SNAIL family" CG3956 16-Dec-15 2015_12 "ENSDARG00000040046(snai2),ENSDARG00000046019(snai1b),ENSDARG00000056995(snai1a)" "YPR015C(),YPR013C()" WBGene00000468(ces-1) ENSXETG00000025115() "ENSMUSG00000022676(Snai2),ENSMUSG00000042821(Snai1),ENSMUSG00000006587(Snai3)" "ENSG00000019549(SNAI2),ENSG00000124216(SNAI1),ENSG00000185669(SNAI3)" " embryonic stage | stage 11 , embryonic stage | stage 13 , embryonic stage , embryonic stage , embryonic stage | stage 5 , embryonic stage | cellular blastoderm , embryonic stage | stage 14-17 , larval stage | first instar , embryonic stage | cycle 14 , embryonic stage | stage 10 , embryonic stage | embryonic cycle 13 , embryonic stage | stage 11-14 , embryonic stage | stage 9-10 , embryonic stage | stage 6 , embryonic stage | stage 4 " " neuroblast

, ganglion mother cell

, head mesoderm

, mesoderm | presumptive

, dorsal mesothoracic disc | precursor

, Bolwig's organ | precursor

, embryonic peripheral nervous system

, dorsal mesothoracic disc

, mesoderm anlage

, dorsal metathoracic disc | precursor

, dorsal metathoracic disc

,

ventral , C1 chordotonal organ precursor cell

, neuroblast | precursor

, ventral neurogenic region | restricted

, organism | ventral & posterior

, central nervous system

" " embryonic stage | cellular blastoderm , embryonic stage | stage 13-15 , embryonic stage | stage 15 , embryonic stage , embryonic stage | stage 7 , embryonic stage | blastoderm , embryonic stage | stage 9-11 , embryonic stage | stage 6 , embryonic stage | stage 5 " " mesoderm | presumptive

, dorsal metathoracic disc | presumptive

, genital disc | presumptive

, embryonic neuron

, posterior transverse furrow

, cephalic furrow

, dorsal mesothoracic disc | presumptive

, anterior transverse furrow

, ventral neurogenic region

, anterior midgut proper primordium

, mesoderm

, ventral thoracic disc | presumptive

" "visible,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,neuroanatomy defective,viable" "scutellar bristle,ventral furrow,denticle belt,anterior scutellar bristle,posterior scutellar bristle,eye,ommatidium,interommatidial bristle,postalar bristle,dorsocentral bristle,notopleural bristle,upper humeral bristle,anterior postalar bristle,mesoderm,visceral mesoderm,cardioblast,embryonic/larval pericardial cell,precursor,endoderm,gastrula embryo,adult thorax,haltere,Malpighian tubule,Malpighian tubule tip cell,embryonic/larval hindgut,embryo,ventral,anterior midgut primordium,posterior midgut primordium,adult Malpighian tubule Type II cell,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,principal midgut epithelial cell,retina,scutellar bristle & trichogen cell455.2,scutellar bristle & tormogen cell455.2,embryonic/first instar larval cuticle,yolk" FBgn0024913 Actë_ Activin-ë_ http://flybase.net/reports/FBgn0024913.html FBgn0065994 protein_coding_gene "0005160=transforming growth factor beta receptor binding, 0008083=growth factor activity" "0016049=cell growth, 0048813=dendrite morphogenesis" 0005576=extracellular region "activin beta, activin, Activan, activin-beta, activin-b, actbeta, Act, Activin, dACT, CG11062, activin 102F, dact, Act-beta, dAct, dActivin, anon-WO02059370.79, beta-Activin, Activin beta, act" "IPR015615=Transforming growth factor-beta-related, IPR001839=Transforming growth factor-beta, C-terminal, IPR002405=Inhibin, alpha subunit, IPR017948=Transforming growth factor beta, conserved site, IPR029034=Cystine-knot cytokine" CG11062 16-Dec-15 2015_12 "ENSDARG00000070303,ENSDARG00000040777(inhbb),ENSDARG00000012671(inhbaa),ENSDARG00000024759(inhbab),ENSDARG00000040780(LOC100329520)" ENSXETG00000017149() "ENSMUSG00000037035(Inhbb),ENSMUSG00000041324(Inhba)" "ENSG00000163083(INHBB),ENSG00000122641(INHBA),ENSG00000175189(INHBC)" " embryonic stage , embryonic stage&&larval stage&&adult stage " " embryonic central nervous system

, sensory mother cell

, ventral nerve cord

, neuroblast

, embryonic peripheral nervous system

" "lethal,recessive,visible,neuroanatomy defective,cell growth defective,viable,circadian rhythm defective,heat sensitive" "wing vein,distal medullary amacrine neuron Dm8,optic lobe,photoreceptor cell R7,somatic clone,central nervous system,wing" FBgn0020912 Ptx1 Ptx1 http://flybase.net/reports/FBgn0020912.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0048813=dendrite morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter" "0005634=nucleus, 0005667=transcription factor complex" "ptx1, Ptx, CG1447, D-Ptx1" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR003654=OAR domain, IPR001356=Homeobox domain" CG1447 16-Dec-15 2015_12 "ENSXETG00000013330(pitx2),ENSXETG00000010022(PITX3),ENSXETG00000010401(pitx1)" " embryonic stage | stage 4 , embryonic stage | stage 8 " "

posterior , proctodeum

,

0-10% egg length " " embryonic stage | stage 11-13 , embryonic stage | stage 16 , embryonic stage | stage 15 " " midgut

, central nervous system | segmentally repeated

, somatic muscle | segmentally repeated

, midgut constriction 2

" viable FBgn0003719 tld tolloid http://flybase.net/reports/FBgn0003719.html protein_coding_gene "0008270=zinc ion binding, 0005509=calcium ion binding, 0004222=metalloendopeptidase activity" "0017015=regulation of transforming growth factor beta receptor signaling pathway, 0007362=terminal region determination, 0009880=embryonic pattern specification, 0006508=proteolysis, 0008586=imaginal disc-derived wing vein morphogenesis, 0007313=maternal specification of dorsal/ventral axis, oocyte, soma encoded, 0007352=zygotic specification of dorsal/ventral axis, 0007378=amnioserosa formation, 0008293=torso signaling pathway, 0030513=positive regulation of BMP signaling pathway, 0010629=negative regulation of gene expression, 0016485=protein processing" 0005576=extracellular region "Tolloid, CG6868, dTld, TLD, CT21278, Tld" "IPR000859=CUB domain, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR001506=Peptidase M12A, astacin, IPR018097=EGF-like calcium-binding, conserved site, IPR015446=Bone morphogenetic protein 1/tolloid-like protein, IPR000742=EGF-like domain, IPR006026=Peptidase, metallopeptidase, IPR024079=Metallopeptidase, catalytic domain, IPR001881=EGF-like calcium-binding domain" CG6868 16-Dec-15 2015_12 "ENSDARG00000037429(tll1),ENSDARG00000028053(bmp1b),ENSDARG00000055884,ENSDARG00000028071(bmp1a)" WBGene00003555(nas-39) "ENSXETG00000007493(TLL2),ENSXETG00000010536(bmp1),ENSXETG00000017032(TLL1)" "ENSMUSG00000025013(Tll2),ENSMUSG00000022098(Bmp1),ENSMUSG00000053626(Tll1)" " larval stage | third instar , embryonic stage | stage 8-9 , embryonic stage | early , embryonic stage , embryonic stage | stage 11 , embryonic stage | cellular blastoderm " " imaginal disc

, embryonic maxillary segment | restricted

,

dorsal , eye-antennal disc

, embryonic labial segment | restricted

, larval optic lobe

, tracheal pit

, morphogenetic furrow | anterior to

, embryonic central nervous system | primordium | restricted

, embryonic mandibular segment | restricted

" embryonic stage | blastoderm

dorsal "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,wild-type,visible,lethal - all die before end of pupal stage,temperature conditional,some die during pupal stage,heat sensitive,viable" "embryonic leading edge cell,embryonic epidermis,ommatidium,brain,epidermis,dorsal,amnioserosa,embryo,cephalic furrow,extended germ band embryo,denticle belt,egg operculum,maternal effect,somatic clone,dorsal appendage,embryonic ventral epidermis,embryonic dorsal epidermis,polytene chromosome,visceral mesoderm,embryonic/larval dorsal vessel,posterior crossvein,wing vein,wing" FBgn0259209 Mlp60A Muscle LIM protein at 60A http://flybase.net/reports/FBgn0259209.html "FBgn0011643, FBgn0013299, FBgn0014862, FBgn0047165, FBgn0053149, FBgn0062900, FBgn0050174, FBgn0050179" protein_coding_gene 0008270=zinc ion binding "0060537=muscle tissue development, 0016202=regulation of striated muscle tissue development" "0030018=Z disc, 0005634=nucleus, 0005737=cytoplasm, 0015629=actin cytoskeleton" "MLP, CG30174, Muscle-specific LIM protein at 60A, BcDNA:RH74176, DLim-2, CG3220, Mlp60, dMlp60A, BcDNA:RE14544, Mlp1, CG30179, CG33149, DmLIM-2, CG42309, DMlp1, FBgn0259209, MLP1, Muscle LIM protein 60A, DMLP1, MLIM 60A" "IPR001781=Zinc finger, LIM-type" CG42309 16-Dec-15 2015_12 " embryonic stage | stage >=13 , embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage , embryonic stage -- adult stage " " visceral mesoderm

, somatic mesoderm

, embryonic/larval somatic muscle

, pharyngeal muscle

" embryonic stage " pharyngeal muscle

, embryonic/larval somatic muscle

, larval visceral muscle

" FBgn0264442 ab abrupt http://flybase.net/reports/FBgn0264442.html "FBgn0259750, FBgn0259599, FBgn0000011, FBgn0013436, FBgn0022233, FBgn0052830" protein_coding_gene "0003676=nucleic acid binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046872=metal ion binding" "0016198=axon choice point recognition, 0044719=regulation of imaginal disc-derived wing size, 0016319=mushroom body development, 0007423=sensory organ development, 0048666=neuron development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007517=muscle organ development, 0008039=synaptic target recognition, 0007298=border follicle cell migration, 0048813=dendrite morphogenesis, 0016203=muscle attachment" 0005634=nucleus "l(2)k02807, parted, CG4807, clu, CG32830, ptd, CG43860, clueless, B2149, Ab, Abrupt" "IPR007087=Zinc finger, C2H2, IPR011333=POZ domain, IPR015880=Zinc finger, C2H2-like, IPR000210=BTB/POZ domain, IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain" CG43860 16-Dec-15 2015_12 ENSG00000173276(ZNF295) " larval stage , embryonic stage | stage >=9 , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage >=11 " " eye-antennal disc

, ventral midline

, dorsal mesothoracic disc

, embryonic stomatogastric nervous system

, larval muscle system

, imaginal disc

, epidermis

, VUM precursor

" " larval stage , embryonic stage | stage >=14 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage >=9 " " eye-antennal disc

, imaginal disc

, dorsal mesothoracic disc

, larval muscle system

, embryonic stomatogastric nervous system

, epidermis

, ventral midline

, VUM precursor

" FBgn0000071 Ama Amalgam http://flybase.net/reports/FBgn0000071.html FBgn0015757 protein_coding_gene 0003823=antigen binding 0007155=cell adhesion 0005886=plasma membrane "M109, CT7244, amalgam, AMA, BG:DS00276.6, CG2198, ama" "IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain" CG2198 16-Dec-15 2015_12 "ENSDARG00000034273(sid4),ENSDARG00000009866" ENSXETG00000016639(LSAMP) "ENSMUSG00000040037(Negr1),ENSMUSG00000061080(Lsamp)" "ENSG00000172260(NEGR1),ENSG00000185565(LSAMP)" " embryonic stage , pupal stage " " embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 16 , embryonic stage | stage 8 , embryonic stage | stage 13 , embryonic stage | stage 10 " " embryonic central nervous system | presumptive

, peripheral nervous system

, larval labral segment sense organ | precursor

, mesoderm

, spiracular sensory organ

, amnioserosa

, fat body

, embryonic/larval dorsal vessel

, visceral mesoderm

, hypophysis

, neuron

" partially lethal - majority die FBgn0015553 tos tosca http://flybase.net/reports/FBgn0015553.html protein_coding_gene "0051908=double-stranded DNA 5'-3' exodeoxyribonuclease activity, 0045145=single-stranded DNA 5'-3' exodeoxyribonuclease activity, 0004518=nuclease activity, 0048256=flap endonuclease activity, 0003677=DNA binding, 0008852=exodeoxyribonuclease I activity" "0006298=mismatch repair, 0006310=DNA recombination" 0005634=nucleus "CG10387, Tosca, DmTosca" "IPR006086=XPG-I domain, IPR019974=XPG conserved site, IPR029060=PIN domain-like, IPR006085=XPG N-terminal, IPR020045=5'-3' exonuclease, C-terminal domain, IPR006084=XPG/Rad2 endonuclease, IPR008918=Helix-hairpin-helix motif, class 2" CG10387 16-Dec-15 2015_12 ENSDARG00000056832(zgc:55521) "YOR033C(EXO1),YDR263C(DIN7)" ENSXETG00000019032(EXO1) ENSMUSG00000039748(Exo1) ENSG00000174371(EXO1) " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-6 , embryonic stage | 0-4 hr , adult stage && oogenesis stage | stage S11-14 , adult stage | female , adult stage && oogenesis stage | stage S9,10 " " germarium region 2a

, oocyte | ubiquitous

, germarium region 2b

, germarium region 3

, border follicle cell

" viable FBgn0025878 wrapper wrapper http://flybase.net/reports/FBgn0025878.html protein_coding_gene "0061564=axon development, 0034349=glial cell apoptotic process, 0008366=axon ensheathment" 0005886=plasma membrane "CG10382, CT19059, Wrapper, Wr" "IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR003961=Fibronectin type III, IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain, IPR007110=Immunoglobulin-like domain" CG10382 16-Dec-15 2015_12 WBGene00006942(wrk-1) " embryonic stage | stage 17 , larval stage | third instar , embryonic stage | stage >=12 " " glial cell &&of embryonic brain

, ventral midline

, midline glial cell

, larval brain

, PNS glial cell

" " embryonic stage | stage 17 , larval stage | third instar , embryonic stage | stage >=12 " " glial cell &&of embryonic brain

, larval brain

, ventral midline

, midline glial cell

" "viable,fertile" "ventral nerve cord commissure,midline glial cell,presumptive embryonic/larval central nervous system" FBgn0003900 twi twist http://flybase.net/reports/FBgn0003900.html "FBtr0071953, FBpp0071864" protein_coding_gene "0042803=protein homodimerization activity, 0046982=protein heterodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007443=Malpighian tubule morphogenesis, 0031032=actomyosin structure organization, 0009950=dorsal/ventral axis specification, 0048747=muscle fiber development, 0007501=mesodermal cell fate specification, 0010004=gastrulation involving germ band extension, 0007507=heart development, 0007500=mesodermal cell fate determination, 0010629=negative regulation of gene expression, 0007375=anterior midgut invagination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0007498=mesoderm development, 0001710=mesodermal cell fate commitment, 0007370=ventral furrow formation, 0016202=regulation of striated muscle tissue development, 0007369=gastrulation, 0007435=salivary gland morphogenesis, 0007499=ectoderm and mesoderm interaction" "0005737=cytoplasm, 0005634=nucleus" "dip5, EC9, CG2956, TWI, Twi, Twist, Tw, twist, DTwist, bHLHb17" "IPR015789=Twist-related, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG2956 16-Dec-15 2015_12 WBGene00001952(hlh-6) "ENSXETG00000024100(NEUROG2),ENSXETG00000007898(NEUROG1),ENSXETG00000026423(NEUROG3),ENSXETG00000015140(NEUROD2),ENSXETG00000023427(NEUROD6)" ENSMUSG00000035799(Twist1) " embryonic stage | 2-10 hr , embryonic stage | cellular blastoderm , embryonic stage | stage 6 , embryonic stage | stage 8 , embryonic stage | stage 5 " " ectoderm | presumptive

, mesoderm | presumptive

, mesoderm

,

ventral compartment " " embryonic stage | stage 7-10 , embryonic stage | cellular blastoderm , embryonic stage | stage 6 , embryonic stage | stage 12-14 , embryonic stage--pupal stage , embryonic stage | stage 5 , embryonic stage | stage 7-8 " " mesoderm

, ectoderm | presumptive

, mesoderm | presumptive

, larval visceral muscle

, mesectoderm

, mesothoracic tergum && myoblast

, embryonic/larval somatic muscle

,

ventral , anterior midgut proper primordium

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,visible,heat sensitive,neuroanatomy defective,flight defective,viable" "principal midgut epithelial cell,ventral furrow,embryo,ventral,visceral mesoderm,endoderm,dorsal medial muscle,oblique muscle,wing,mesothoracic extracoxal depressor muscle 66,skeletal muscle of abdomen,embryonic/larval somatic muscle,indirect flight muscle,direct flight muscle,heat sensitive,anterior midgut primordium,posterior midgut primordium,longitudinal visceral muscle primordium,circular visceral muscle fiber,embryonic somatic muscle,visceral muscle primordium,embryonic/larval pericardial cell,embryonic/larval heart,ectopic,Malpighian tubule,presumptive embryonic/larval central nervous system,mesoderm,central nervous system,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,corpus cardiacum primordium,presumptive embryonic salivary gland,visceral muscle,embryonic/larval dorsal vessel | embryonic stage,cardioblast,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,embryonic epidermis,myoblast | P-stage" FBgn0261836 Msp300 Muscle-specific protein 300 kDa http://flybase.net/reports/FBgn0261836.html "FBgn0053715, FBgn0001926, FBgn0010070, FBgn0010270, FBgn0031686, FBgn0031687, FBgn0047188, FBgn0051649, FBgn0051916, FBgn0053549, FBgn0062498, FBgn0063615, FBgn0064983, FBgn0065020, FBgn0011271, FBgn0260952, FBgn0031685" protein_coding_gene "0051015=actin filament binding, 0019901=protein kinase binding, 0008092=cytoskeletal protein binding, 0005515=protein binding, 0003779=actin binding" "0040023=establishment of nucleus localization, 0007519=skeletal muscle tissue development, 0007523=larval visceral muscle development, 0060361=flight, 0051643=endoplasmic reticulum localization, 0051647=nucleus localization, 0007303=cytoplasmic transport, nurse cell to oocyte, 0007498=mesoderm development, 0006997=nucleus organization, 0007010=cytoskeleton organization, 0040011=locomotion, 0007015=actin filament organization, 0034453=microtubule anchoring, 0051646=mitochondrion localization, 0016477=cell migration, 0008335=female germline ring canal stabilization, 0090286=cytoskeletal anchoring at nuclear membrane" "0005635=nuclear envelope, 0030018=Z disc, 0005884=actin filament, 0005640=nuclear outer membrane, 0008305=integrin complex, 0005737=cytoplasm, 0015629=actin cytoskeleton, 0034993=LINC complex, 0048471=perinuclear region of cytoplasm" "repetitive ORF, CG33549, CG31649, Muscle-specific protein 300, FBgn0010070, BcDNA:LP10936, Msp-300, Box B-binding factor 1, MSP-300, Bbbf1, BcDNA:GH18470, msp-300, Nesprin, jf22, Spec25CD, CG14035, CG33715, nesprin, CG42768, CG18252, l(2)25Ch, msp300, lethal(2)25Ch, BcDNA:GH02446, BBF-1, MSP300, BcDNA:AT10293, Msp300, l(2)jf22, Muscle-specific protein-300, CG18251, CG31916" "IPR018159=Spectrin/alpha-actinin, IPR030265=Nesprin-1, IPR001589=Actinin-type actin-binding domain, conserved site, IPR030266=Nesprin-2, IPR012315=KASH domain, IPR002017=Spectrin repeat, IPR001715=Calponin homology domain" CG42768 16-Dec-15 2015_12 " larval stage , adult stage , embryonic stage " embryonic stage " muscle attachment site

, larval visceral muscle

, larval muscle system

" FBgn0263237 Cdk7 Cyclin-dependent kinase 7 http://flybase.net/reports/FBgn0263237.html "FBgn0015617, FBgn0024324" protein_coding_gene "0004693=cyclin-dependent protein serine/threonine kinase activity, 0004674=protein serine/threonine kinase activity, 0005509=calcium ion binding, 0008353=RNA polymerase II carboxy-terminal domain kinase activity, 0005524=ATP binding, 0000990=core RNA polymerase binding transcription factor activity" "0006468=protein phosphorylation, 0000079=regulation of cyclin-dependent protein serine/threonine kinase activity, 0001111=promoter clearance from RNA polymerase II promoter, 0006366=transcription from RNA polymerase II promoter, 0012501=programmed cell death, 0007067=mitotic nuclear division" "0005675=holo TFIIH complex, 0032806=carboxy-terminal domain protein kinase complex, 0005737=cytoplasm, 0005634=nucleus" "Dmcdk7, CD 7, DmCdk7, DmMO15, cyclin-dependent kinase 7, DmMo15, CG3319, DmCDK7, cdk-7, dCdk7, p40[MO15], Mo15, cdk7, CDK7" "IPR017441=Protein kinase, ATP binding site, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain" CG3319 16-Dec-15 2015_12 ENSDARG00000051916(cdk7) YDL108W(KIN28) WBGene00000408(cdk-7) ENSXETG00000000481(cdk7) ENSMUSG00000069089(Cdk7) ENSG00000134058(CDK7) " adult stage | female , embryonic stage -- adult stage " ovary

FBgn0261385 scra scraps http://flybase.net/reports/FBgn0261385.html "FBgn0004243, FBgn0003340, FBgn0004134, FBgn0010540, FBgn0011558, FBgn0015994" protein_coding_gene "0008017=microtubule binding, 0003779=actin binding, 0005515=protein binding" "0051297=centrosome organization, 0007423=sensory organ development, 0032189=maintenance of actomyosin contractile ring localization, 0000281=mitotic cytokinesis, 0007112=male meiosis cytokinesis, 0032465=regulation of cytokinesis, 0045035=sensory organ precursor cell division, 0051533=positive regulation of NFAT protein import into nucleus, 0007349=cellularization, 0043063=intercellular bridge organization, 0007009=plasma membrane organization, 0030726=male germline ring canal formation, 0022008=neurogenesis, 0008356=asymmetric cell division, 0031106=septin ring organization" "0032154=cleavage furrow, 0045172=germline ring canal, 0005737=cytoplasm, 0035323=male germline ring canal, 0005634=nucleus, 0070938=contractile ring, 0005826=actomyosin contractile ring" "unnamed, ABP8, Anillin, l(2)03427, Actin-binding protein 8, Ani, l(2)k08255, lethal (2) k08255, Anil, anil, annilin, anillin, ani, Abp8, l(2)43Ec, CG2092, Scra, Scraps" "IPR012966=Anillin homology domain, IPR001849=Pleckstrin homology domain, IPR011993=Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)" CG2092 16-Dec-15 2015_12 ENSDARG00000060917(si:ch211-197n10.2) WBGene00013038(ani-1) ENSXETG00000000343(ANLN) ENSMUSG00000036777(Anln) ENSG00000011426(ANLN) " , embryonic stage -- adult stage " cell

DRSC07679 K 0.303458739 0.006738071 0.279153167 -0.139493592 0.639625796 1.812448036 FBgn0019643 Dat Dopamine N acetyltransferase http://flybase.net/reports/FBgn0019643.html FBgn0000418 protein_coding_gene "0004059=aralkylamine N-acetyltransferase activity, 0008080=N-acetyltransferase activity, 0004060=arylamine N-acetyltransferase activity" "0046334=octopamine catabolic process, 0042429=serotonin catabolic process, 0006584=catecholamine metabolic process, 0045187=regulation of circadian sleep/wake cycle, sleep, 0048066=developmental pigmentation, 0042420=dopamine catabolic process, 0030431=sleep" 0005737=cytoplasm "Arylalkylamine N-acetyltransferase-1, DAT, arylalkylamine N-acetyltransferase, Aanat1, Dopamine acetyltransferase, AANATA, AANAT, aaNAT1, NAT1, aaNat, Arylalkylamine N-acetyltransferase, AANATB, CG3318, AA-NAT1, Dat1, Dopamine N-acetyltransferase, aaNAT" "IPR016181=Acyl-CoA N-acyltransferase, IPR000182=GNAT domain" CG3318 16-Dec-15 2015_12 "WBGene00010887(M7.12),WBGene00010884(M7.8),WBGene00011046(R05H10.7),WBGene00020940(W02D7.4),WBGene00020941(W02D7.5),WBGene00011042(R05H10.1)" " embryonic stage , embryonic stage | stage >=15 , embryonic stage | stage >=14 " " tracheal system

, anterior embryonic/larval midgut

, embryonic brain

, embryonic central nervous system

, embryonic nervous system

, oenocyte

, amnioserosa

, posterior embryonic/larval midgut

, ventral nerve cord

, proventriculus

" "behavior defective,recessive,lethal" FBgn0000927 fs(1)Ya female sterile (1) Young arrest http://flybase.net/reports/FBgn0000927.html protein_coding_gene 0005515=protein binding "0007344=pronuclear fusion, 0030261=chromosome condensation, 0007067=mitotic nuclear division, 0006260=DNA replication, 0006997=nucleus organization, 0000280=nuclear division, 0006333=chromatin assembly or disassembly" "0005635=nuclear envelope, 0005652=nuclear lamina, 0005654=nucleoplasm, 0005737=cytoplasm" "CG2707, Young arrest, fs(1)73, fs(1)Y[a], fs(1)Y2, young arrest, fs(1)M12, EG:95B7.4, Ya, Young Arrest, YA" CG2707 16-Dec-15 2015_12 " embryonic stage | 0-2 hr , adult stage && oogenesis stage " " oocyte

, nurse cell

" " embryonic stage , adult stage && oogenesis stage , embryonic stage | stage 1-4 " " polar body nucleus

, nurse cell

, organism

, male pronucleus

, oocyte

, ovary

, yolk nucleus

, female pronucleus

" "viable,fertile,wild-type,electrophoretic variant,female sterile,recessive,fully,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,cell cycle defective,female fertile" "egg,maternal effect,embryo,cell cycle,fertilized egg,unfertilized egg" FBgn0019990 Gcn2 Gcn2 http://flybase.net/reports/FBgn0019990.html protein_coding_gene "0004686=elongation factor-2 kinase activity, 0004672=protein kinase activity, 0005524=ATP binding" "0000398=mRNA splicing, via spliceosome, 0006468=protein phosphorylation, 0006417=regulation of translation, 0045793=positive regulation of cell size" "0071013=catalytic step 2 spliceosome, 0071011=precatalytic spliceosome, 0005829=cytosol" "EIF2, general control nonderepressing 2 kinase, Gcn-2, GCN2, DGCN2, dGCN2, CG1609, GC nonderepressing 2 kinase" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR016135=Ubiquitin-conjugating enzyme/RWD-like, IPR008271=Serine/threonine-protein kinase, active site, IPR006575=RWD domain" CG1609 16-Dec-15 2015_12 YDR283C(GCN2) WBGene00013591(gcn-2) ENSMUSG00000005102(Eif2ak4) ENSG00000128829(EIF2AK4) " embryonic stage | early , embryonic stage | stage >=12 , embryonic stage | stage 8-11 , embryonic stage | stage 14 , embryonic stage | stage 6 , embryonic stage | late , embryonic stage | stage 12-14 , embryonic stage | stage >=13 , embryonic stage -- adult stage , embryonic stage | stage 16-17 " " embryonic central nervous system

, mesoderm

, embryonic/larval hindgut

, posterior midgut proper primordium

, amnioproctodeal invagination

, neuron

, anterior midgut proper primordium

, cephalic furrow

, ventral furrow

, anterior embryonic/larval midgut

, embryonic brain | primordia

, anterior transverse furrow

, embryonic central nervous system | restricted

, posterior embryonic/larval midgut

, posterior transverse furrow

, ventral nerve cord

" "immune response defective,majority die during P-stage,viable" FBgn0086680 vvl ventral veins lacking http://flybase.net/reports/FBgn0086680.html "FBgn0003995, FBgn0010170, FBgn0000285, FBgn0003146, FBgn0011727" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0001228=RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding" "0007422=peripheral nervous system development, 0048813=dendrite morphogenesis, 0048814=regulation of dendrite morphogenesis, 0006355=regulation of transcription, DNA-templated, 0007425=epithelial cell fate determination, open tracheal system, 0007420=brain development, 0008045=motor neuron axon guidance, 0002807=positive regulation of antimicrobial peptide biosynthetic process, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035284=brain segmentation" 0005634=nucleus "Drifter/Ventral veinless, VVL, Dfr/Vvl, Ventral veins lacking, CG10037, Ventral Veinless, dfr, ventral veinless, Cfla, Drifter, paired-like 3, Dfr, u-turn, drifter, dfr-vvl, dfr/vvl, Cf1a, Vv1, Vvl, Drf, sep, PRD gene 3, drf, U-turn, prd3, DFR, separated, Cf1-a, vvl/dfr, Cf1a/drifter, vvl/dfr/ut, Ventral veinless, ut" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR013847=POU domain, IPR010982=Lambda repressor-like, DNA-binding domain, IPR000327=POU-specific domain, IPR016362=POU-domain transcription factor, class 3, IPR001356=Homeobox domain" CG10037 16-Dec-15 2015_12 "ENSDARG00000007996(pou2f1b),ENSDARG00000043682,ENSDARG00000019658,ENSDARG00000036816(LOC100002311)" "ENSMUSG00000052621(Pou3f2),ENSMUSG00000045515(Pou3f3),ENSMUSG00000056854(Pou3f4)" "ENSG00000184486(POU3F2),ENSG00000198914(POU3F3),ENSG00000196767(POU3F4),ENSG00000185668(POU3F1)" " embryonic stage | mid , embryonic stage , oogenesis stage , embryonic stage | late , embryonic stage | < 8-12 hr , embryonic stage | <8-12 hr " " tracheal primordium

, glial cell

, mesectoderm

, ventral midline

, supraesophageal ganglion

, central nervous system | restricted

, embryonic peripheral nervous system | restricted

, neuron

, ventral nerve cord

, ectoderm

" " embryonic stage | stage 10,11 , embryonic stage | stage 13-17 , embryonic stage | stage >10 , embryonic stage | late , embryonic stage | stage 10-12 , embryonic stage | stage 10-11 , embryonic stage | stage 10 , embryonic stage | stage 13-15 , embryonic stage | stage 13-16 , embryonic stage | stage >=10 " " labral segment | restricted

, epidermis

, embryonic/larval tracheal pit

, central nervous system | restricted

, ventral midline

, labrum | restricted

, tracheal primordium

, serotonergic neuron

, embryonic/larval hindgut

, RP neuron

, abdominal 1--7 larval oenocyte group

, midline glial cell

, procephalic segment | restricted

" FBgn0002440 l(3)mbn lethal (3) malignant blood neoplasm http://flybase.net/reports/FBgn0002440.html protein_coding_gene "0008010=structural constituent of chitin-based larval cuticle, 0005214=structural constituent of chitin-based cuticle" "0042387=plasmatocyte differentiation, 0022416=chaeta development, 0035220=wing disc development, 0040003=chitin-based cuticle development" "0031012=extracellular matrix, 0005886=plasma membrane, 0005737=cytoplasm" "l(3)mbn1, lethal(3)malignant blood neoplasm-1, l(3)mbn-1, CG12755, l(3)malignant blood neoplasm1, MBN" IPR000618=Insect cuticle protein CG12755 16-Dec-15 2015_12 " larval stage , embryonic stage && larval stage , pupal stage&&adult stage , pupal stage && adult stage " " proplasmatocyte

, embryonic/larval digestive system

, plasmatocyte

, pericardial cell

, embryonic/larval fat body

, embryonic/larval trachea

, hemolymph

, lymph gland

" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,immune response defective,melanotic mass phenotype,viable" "melanotic mass,embryonic/larval lymph gland,plasmatocyte,podocyte,crystal cell,lamellocyte,ectopic,hemocyte" DRSC08793 I 1.654498783 0.729003592 0.283274474 0.323824116 -0.362590179 -0.162480976 FBgn0025776 ind intermediate neuroblasts defective http://flybase.net/reports/FBgn0025776.html protein_coding_gene "0008134=transcription factor binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007389=pattern specification process, 0007398=ectoderm development, 0007420=brain development, 0006355=regulation of transcription, DNA-templated, 0007419=ventral cord development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0010629=negative regulation of gene expression, 0007417=central nervous system development, 0009953=dorsal/ventral pattern formation, 0007400=neuroblast fate determination, 0006357=regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "Intermediate neuroblasts defective, ind/Gsx, CG11551, intermediate nerve cord defective, Ind" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain" CG11551 16-Dec-15 2015_12 "ENSDARG00000070496,ENSDARG00000043322(gsx2),ENSDARG00000035735(gsx1)" "ENSXETG00000021967(hoxb3),ENSXETG00000000717(HOXA3),ENSXETG00000001800(HOXD3)" " embryonic stage | stage 8 , embryonic stage | stage 9-11 , embryonic stage | stage 9 , embryonic stage | stage 5-8 , embryonic stage | 2-8 hr " " stage 1 neuroblast | subset

, neuroblast | subset

, neuroblast NB5-3

, deuterocerebral neuroblast | subset

, neuroblast NB3-2

, ventral neurogenic region && embryonic ocular segment | medial & restricted

, ventral neurogenic region | restricted

, neuroblast NB7-2

, ventral neurogenic region && embryonic antennal segment | medial & restricted

, neuroblast NB6-2

, ventral neurogenic region && embryonic intercalary segment | medial & restricted

, procephalic neuroblast | subset

, neuroblast NB4-2

, tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

" " embryonic stage | stage 5-8 , embryonic stage | stage 8-13 " " ventral neurogenic region | restricted

, neuroblast | subset

" "neuroanatomy defective,viable" "neuroblast of ventral nerve cord primordium,RP2 motor neuron,intermediate ventral neurectoderm" FBgn0264403 FCG-F http://flybase.net/reports/FBgn0264403.html gene 16-Dec-15 2015_12 "follicle cell,somatic clone" FBgn0004889 tws twins http://flybase.net/reports/FBgn0004889.html "FBgn0004906, FBgn0010249, FBgn0010748, FBgn0010780, FBgn0011012, FBgn0011434, FBgn0028118, FBgn0037791, FBgn0060325, FBgn0060355, FBgn0060382, FBgn0060393, FBgn0060451, FBgn0060476, FBgn0060482, FBgn0060490, FBgn0060503, FBgn0060530, FBgn0060599, FBgn0060620, FBgn0060667, FBgn0060680, FBgn0060683, FBgn0060685, FBgn0060686, FBgn0060717, FBgn0060727, FBgn0060736, FBgn0060738, FBgn0060744, FBgn0060764, FBgn0060771, FBgn0060777, FBgn0060782, FBgn0060814, FBgn0060817, FBgn0060835, FBgn0060851, FBgn0060857, FBgn0060858, FBgn0060872, FBgn0060877, FBgn0060907, FBgn0060908, FBgn0060915, FBgn0060916, FBgn0060954, FBgn0060957, FBgn0060959, FBgn0060962, FBgn0060965, FBgn0060971, FBgn0060972, FBgn0060974, FBgn0060977, FBgn0060995, FBgn0060996, FBgn0061006, FBgn0061008, FBgn0061016, FBgn0061017, FBgn0061018, FBgn0061025, FBgn0061026, FBgn0061030, FBgn0061036, FBgn0061050, FBgn0061051, FBgn0061053, FBgn0061055, FBgn0061059, FBgn0061060, FBgn0061062" protein_coding_gene "0004722=protein serine/threonine phosphatase activity, 0008601=protein phosphatase type 2A regulator activity" "0050821=protein stabilization, 0000278=mitotic cell cycle, 0045201=maintenance of neuroblast polarity, 0001700=embryonic development via the syncytial blastoderm, 0016055=Wnt signaling pathway, 0007406=negative regulation of neuroblast proliferation, 0006470=protein dephosphorylation, 0007091=metaphase/anaphase transition of mitotic cell cycle, 0007099=centriole replication, 0051297=centrosome organization, 0007447=imaginal disc pattern formation, 0007423=sensory organ development" "0005634=nucleus, 0000159=protein phosphatase type 2A complex, 0005737=cytoplasm, 0005829=cytosol, 0005875=microtubule associated complex" "l(3)S053011, CG6235, l(3)S043029, l(3)S110815, l(3)01436, l(3)S029403, l(3)S049902, PR55, l(3)S101413b, DPR55, l(3)S048006, l(3)S026326, tw, l(3)S046918, l(3)s1801, l(3)S022361, aar, protein phosphatase type 2A, l(3)S042630, PP2A-B55, l(3)S060804, protein phosphatase 2a, l(3)S028707, l(3)S105605, l(3)S063110, protein phosphatase 2A, PP2a, dPR55, l(3)S088513, l(3)S029701a, l(3)S032303, regulatory B subunit of type 2A protein phosphatase, l(3)S067109b, l(3)S022205b, l(3)j11C8, Tws, l(3)S067915, PP2A[B], l(3)S134601a, l(3)S027313, 1466/06, l(3)S029110, l(3)S141309, phosphoprotein phosphatase 2A 55 kDa, l(3)S066813, l(3)S132907, l(3)S061915, abnormal anaphase resolution, l(3)S023206, l(3)S146606, l(3)S024834a, l(3)S023013, Twins, l(3)S023141a, l(3)S025806, l(3)S023938, B/PR55, l(3)S025913, l(3)S052810, l(3)S033903, l(3)S091905, PP2A, l(3)S022440, l(3)S023309, l(3)S110008a, l(3)S066017, l(3)S119908, l(3)S042629, PP2A regulatory subunit, l(3)S060203, l(3)S026226, dPP2A-Balpha, dPP2A-B55, l(3)S075902b, tws/aar, PP2A regulatory subunit Twins, dPP2A, l(3)S035505b, l(3)S075515b, l(3)S025832, l(3)S024455, l(3)S061805, l(3)S069206a, l(3)S032708c, l(3)S048507, l(3)S048013, Protein phosphatase 2A at 85F, l(3)S045519, l(3)S043008b, l(3)S076415, l(3)S024838, l(3)S080409, Pp2A-85F, 2414, l(3)S031006, l(3)S111515, v158, l(3)S075110, l(3)02414, l(3)S027127" "IPR000009=Protein phosphatase 2A regulatory subunit PR55, IPR018067=Protein phosphatase 2A regulatory subunit PR55, conserved site, IPR001680=WD40 repeat, IPR017986=WD40-repeat-containing domain, IPR015943=WD40/YVTN repeat-like-containing domain" CG6235 16-Dec-15 2015_12 "ENSDARG00000030725(zgc:76887),ENSDARG00000006624(ppp2r2d),ENSDARG00000053673(ppp2r2b)" YGL190C(CDC55) WBGene00006352(sur-6) "ENSXETG00000010159(ppp2r2a),ENSXETG00000020864(ppp2r2b),ENSXETG00000011604(PPP2R2C)" "ENSMUSG00000022052(Ppp2r2a),ENSMUSG00000041769(Ppp2r2d)" "ENSG00000221914(PPP2R2A),ENSG00000156475(PPP2R2B),ENSG00000175470(PPP2R2D)" " pupal stage | late , embryonic stage | mid-late , adult stage && oogenesis stage , embryonic stage | late , larval stage , adult stage && oogenesis stage | stage >=S6 , pupal stage && spermatogenesis | late , embryonic stage | syncytial blastoderm , larval stage | third instar , pupal stage&&spermatogenesis | late , pupal stage && spermatogenesis " " imaginal disc

, neuroblast

, oocyte

, embryonic/larval hindgut

, eye-antennal disc

, nurse cell

, anal pad

, gonad

, optic lobe

, testis

, Malpighian tubule

, larval central nervous system

, embryonic central nervous system

, ventral thoracic disc

, dorsal mesothoracic disc

" " larval stage , embryonic stage&&larval stage&&pupal stage " " imaginal disc

, larval central nervous system

, embryonic/larval salivary gland

" "some die during larval stage,lethal - all die before end of larval stage,recessive,lethal,lethal - all die before end of prepupal stage,some die during prepupal stage,partially lethal - majority die,increased cell number,somatic clone,cell shape defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell size,polyphasic,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,meiotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,uncoordinated,behavior defective,some die during immature adult stage,female sterile,increased cell death,short lived,heat sensitive,neuroanatomy defective,progressive,locomotor rhythm defective,viable,visible,body color defective" "wing disc,macrochaeta,wing margin,somatic clone,mitochondrion,embryonic/larval neuroblast,supernumerary,embryonic/larval optic lobe,abdomen,maternal effect,neuroblast,mitotic cell cycle,mitotic anaphase,germarium,ovary,testis,ganglion,chromosome, centromeric region,larval brain & nuclear chromosome,posterior compartment,haltere disc,wing margin bristle,ectopic,spindle & neuroblast,mitotic anaphase & neuroblast,mitotic metaphase & neuroblast,eye,nuclear chromosome & mitotic anaphase,chromatin & mitotic anaphase,trichogen cell,tormogen cell,microchaeta,thecogen cell,eo neuron,trichome of the posterior wing margin,adult brain,progressive,mitochondrionelav.PU,mitochondrionen.PU,mesothoracic tergum" DRSC17092 E -0.887862963 -1.475691949 -2.006805725 -2.616713971 0.201475371 0.206109779 FBgn0036208 CG10361 http://flybase.net/reports/FBgn0036208.html protein_coding_gene "0008890=glycine C-acetyltransferase activity, 0030170=pyridoxal phosphate binding" "0009058=biosynthetic process, 0006520=cellular amino acid metabolic process, 0006567=threonine catabolic process" 0005739=mitochondrion "IPR015424=Pyridoxal phosphate-dependent transferase, IPR001917=Aminotransferase, class-II, pyridoxal-phosphate binding site, IPR011282=2-amino-3-ketobutyrate coenzyme A ligase, IPR004839=Aminotransferase, class I/classII, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2" CG10361 16-Dec-15 2015_12 ENSDARG00000005643(gcat) WBGene00012007(T25B9.1) ENSXETG00000015966(gcat) ENSMUSG00000006378(Gcat) ENSG00000100116(GCAT) "viable,fertile" FBgn0261797 Dhc64C Dynein heavy chain 64C http://flybase.net/reports/FBgn0261797.html "FBgn0010349, FBgn0001059, FBgn0003565" protein_coding_gene "0003774=motor activity, 0042623=ATPase activity, coupled, 0003777=microtubule motor activity, 0005524=ATP binding" "0050658=RNA transport, 0040003=chitin-based cuticle development, 0040001=establishment of mitotic spindle localization, 0051237=maintenance of RNA location, 0045478=fusome organization, 0008088=axon cargo transport, 0048477=oogenesis, 0016319=mushroom body development, 0007405=neuroblast proliferation, 0007279=pole cell formation, 0007067=mitotic nuclear division, 0048813=dendrite morphogenesis, 0045197=establishment or maintenance of epithelial cell apical/basal polarity, 0034501=protein localization to kinetochore, 0007051=spindle organization, 0007282=cystoblast division, 0030723=ovarian fusome organization, 0048311=mitochondrion distribution, 0051642=centrosome localization, 2001019=positive regulation of retrograde axon cargo transport, 0007312=oocyte nucleus migration involved in oocyte dorsal/ventral axis specification, 0007018=microtubule-based movement, 0046604=positive regulation of mitotic centrosome separation, 0051683=establishment of Golgi localization, 0030071=regulation of mitotic metaphase/anaphase transition, 0048134=germ-line cyst formation, 0007349=cellularization, 0007298=border follicle cell migration, 0035011=melanotic encapsulation of foreign target, 0007294=germarium-derived oocyte fate determination, 0007098=centrosome cycle, 0047497=mitochondrion transport along microtubule, 0043148=mitotic spindle stabilization, 0008298=intracellular mRNA localization, 0007301=female germline ring canal formation, 0006886=intracellular protein transport, 0045198=establishment of epithelial cell apical/basal polarity, 0007052=mitotic spindle organization" "0000776=kinetochore, 0005875=microtubule associated complex, 0005938=cell cortex, 0005794=Golgi apparatus, 0045172=germline ring canal, 0005868=cytoplasmic dynein complex, 0045169=fusome, 0030286=dynein complex, 0005737=cytoplasm, 0030529=ribonucleoprotein complex, 0005739=mitochondrion" "FCP-A, Su(Gl)77, CD, cytoplasmic dynein, Female sterile(3)Laborc, dynein heavy chain 64C, cDhc, Laborc, cytoplasmic dynenin, l(3)64Ca, Dynein heavy-chain, CG7507, dhc64C, Suppressor of Glued 77, Dhc64c, Dynein heavy chain, cytoplasmic Dynein heavy chain, dynein, Cdhc, Fs(3)Laborc, Fs(3)Sz18, Dynein heavy chain 64c, Fs(3)Lab, dynein heavy-chain, Dhc64, HMW MAP, Dhc, cytoplasmic dynein heavy chain, Cytoplasmic dynein, Cytoplasmic dynein heavy chain, DHC64C, dynein heavy chain, dhc64c, Dynein, dynein heavy chain at 64C, dhc, Lab, Dhc46C, DHC, dynein HC, cDhc64C" "IPR004273=Dynein heavy chain domain, IPR013594=Dynein heavy chain, domain-1, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR013602=Dynein heavy chain, domain-2, IPR026983=Dynein heavy chain, IPR003593=AAA+ ATPase domain, IPR024743=Dynein heavy chain, coiled coil stalk, IPR011704=ATPase, dynein-related, AAA domain, IPR024317=Dynein heavy chain, P-loop containing D4 domain" CG7507 16-Dec-15 2015_12 ENSDARG00000014717(dync1h1) YKR054C(DYN1) WBGene00000962(dhc-1) ENSMUSG00000018707(Dync1h1) ENSG00000197102(DYNC1H1) " adult stage | male , adult stage | female , embryonic stage " " ovary

, testis

" stage S10A oocyte

posterior FBgn0004838 Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C http://flybase.net/reports/FBgn0004838.html "FBgn0010261, FBgn0016665, FBgn0019729, FBgn0024845, FBgn0061493" protein_coding_gene "0003730=mRNA 3'-UTR binding, 0003729=mRNA binding, 0005515=protein binding, 0048027=mRNA 5'-UTR binding, 0003697=single-stranded DNA binding, 0000166=nucleotide binding" "0048024=regulation of mRNA splicing, via spliceosome, 0007319=negative regulation of oskar mRNA translation, 0045451=pole plasm oskar mRNA localization, 0045727=positive regulation of translation, 0007317=regulation of pole plasm oskar mRNA localization, 0046331=lateral inhibition, 0007411=axon guidance, 0007298=border follicle cell migration, 0006397=mRNA processing" "0005730=nucleolus, 0043186=P granule, 0005654=nucleoplasm, 0005634=nucleus, 0005737=cytoplasm, 0043234=protein complex, 0030529=ribonucleoprotein complex" "Ov5, hrb27C, rrm7, Hrb48, Hrb27-C, hnRNP27C, HRB27C, HRP48, hrp48, Hrb27c, hrb27c, l(2)10280, hrb27, RRM7, Rbp7, l(2)2647, CG10377, p50, 10280, RNA-binding protein 7, linha, Hrp48/Hrb27C, hnRNP48, Heterogeneous nuclear ribonucleoprotein, l(2)02647, Hrp48" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG10377 16-Dec-15 2015_12 ENSDARG00000070846(dazap1) WBGene00003423(msi-1) ENSXETG00000003704(dazap1) ENSMUSG00000069565(Dazap1) ENSG00000071626(DAZAP1) " oogenesis stage && adult stage | female , embryonic stage -- adult stage , embryonic stage | early " ovary

"neuroanatomy defective,somatic clone,viable,visible,partially lethal - majority die,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,female semi-sterile,germline clone,female sterile,some die during pupal stage" "border follicle cell,somatic clone,egg,chorion,nurse cell & nuclear chromosome,wing margin,oocyte & cytoskeleton | germ-line clone,ommatidium,female,posterior supraalar bristle,germline clone,dorsal appendage,egg operculum,chorion | germline clone,ovary,scutellar bristle,trichogen cell,embryonic/larval hemocyte | third instar larval stage,egg chamber,chaeta,supernumerary,mesothoracic tergum" DRSC03347 K -0.027526998 -1.397433038 0.216716041 0.160620442 -2.080069608 0.689284651 FBgn0005596 yem yemanuclein http://flybase.net/reports/FBgn0005596.html "FBgn0004042, FBgn0040620" protein_coding_gene 0003677=DNA binding "0035042=fertilization, exchange of chromosomal proteins, 0048477=oogenesis, 0007143=female meiotic division" "0005634=nucleus, 0042585=germinal vesicle, 0000776=kinetochore, 0001940=male pronucleus" "CG14513, unnamed, yT4.5, yG4.5, Yemalpha, yema-gene-4.5, Yema nuclein alpha, yemanuclein alpha, yemalpha, yem-alpha, yem, yemanuclein-alpha, yema, CG11879" "IPR014840=Hpc2-related domain, IPR026949=Ubinuclein/Yemanuclein, IPR026947=Ubinuclein middle domain" CG14513 16-Dec-15 2015_12 ENSDARG00000063062(ubn2) "ENSXETG00000013423(UBN2),ENSXETG00000009138(UBN1)" "ENSMUSG00000038538(Ubn2),ENSMUSG00000039473(Ubn1)" "ENSG00000157741(UBN2),ENSG00000118900(UBN1)" " adult stage && oogenesis stage | stage <=S7 , embryonic stage | stage <6 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S7 , adult stage && oogenesis stage | stage >=S10B , embryonic stage | stage <=8 , adult stage && oogenesis stage | stage S8-10A " " oocyte | posterior

, organism

, germarium region 2

, oocyte

, ovary

, oocyte | anterior

" "female sterile,lethal - all die during embryonic stage,maternal effect,partially lethal,viable,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "male pronucleus | maternal effect3450),oocyte" FBgn0003460 so sine oculis http://flybase.net/reports/FBgn0003460.html "FBgn0004392, FBgn0004874" protein_coding_gene "0043565=sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0005515=protein binding, 0008134=transcription factor binding" "0007283=spermatogenesis, 0007623=circadian rhythm, 0001744=optic lobe placode formation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007455=eye-antennal disc morphogenesis, 0009649=entrainment of circadian clock, 0008347=glial cell migration, 0006355=regulation of transcription, DNA-templated, 0048749=compound eye development, 0001745=compound eye morphogenesis, 0001746=Bolwig's organ morphogenesis, 0035271=ring gland development" 0005634=nucleus "CG11121, medusa, med, Sine Oculis, Sine oculis, SO, So, Droplet, ami, sinus oculis, mda, sine oculus, optic lobe defective, old, Drl, absent minded, somda" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG11121 16-Dec-15 2015_12 "ENSDARG00000026473(six1b),ENSDARG00000039304(six1a),ENSDARG00000058004(six2a),ENSDARG00000054878(six2b)" ENSXETG00000016943(SIX1) "ENSMUSG00000051367(Six1),ENSMUSG00000024134(Six2)" "ENSG00000126778(SIX1),ENSG00000170577(SIX2)" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 16 " " epidermis

, eye disc

, optic lobe | presumptive

, embryonic optic lobe primordium

, Bolwig's organ

" " larval stage | third instar , embryonic stage , adult stage | male , adult stage , embryonic stage | stage 9 , embryonic stage | stage 12 , embryonic stage | stage 16 " " eye disc

, embryonic optic lobe primordium

, photoreceptor cell R1--7

, cyst cell

, eye-antennal disc

, optic lobe | presumptive

, ocellus

, epidermis

, Bolwig's organ

, optic lobe

" "visible,viable,fertile,male,neuroanatomy defective,behavior defective,recessive,phototaxis defective,visual behavior defective,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,dominant,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,cell growth defective,somatic clone,circadian rhythm defective,partially lethal - majority live,size defective" "optic lobe,cell body rind of medulla,lobula,eye,optic chiasma,lamina,medulla,photoreceptor cell,precursor,neuroblast & embryonic optic lobe primordium,P5m fiber tract founder cluster,ocellus,visual primordium,Bolwig organ,eye disc & neuron,larval LN period neuron,ectopic,antenna,adult head,wing,eye disc,heat sensitive,glial cell & larval optic lobe,medulla neuropil,ommatidium,lamina & neuron,lamina anlage glial cell,cuticle,somatic clone,subretinal glial cell,morphogenetic furrow,Pdf neuron,retina,eye photoreceptor cell,embryonic/larval optic stalk,embryonic stomatogastric nervous system,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,interfollicle cell,cell non-autonomous,embryonic/larval stomatogastric nervous system,corpus cardiacum primordium,medial ocellus" FBgn0010051 Itp-r83A "Inositol 1,4,5,-tris-phosphate receptor" http://flybase.net/reports/FBgn0010051.html "FBgn0010234, FBgn0010870, FBgn0011378, FBgn0023199, FBgn0066011" protein_coding_gene "0005262=calcium channel activity, 0005220=inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity" "0051209=release of sequestered calcium ion into cytosol, 0060259=regulation of feeding behavior, 0006979=response to oxidative stress, 0030322=stabilization of membrane potential, 0055089=fatty acid homeostasis, 0030536=larval feeding behavior, 0007591=molting cycle, chitin-based cuticle, 0050909=sensory perception of taste, 0006874=cellular calcium ion homeostasis, 0070588=calcium ion transmembrane transport, 0000280=nuclear division, 0042594=response to starvation, 0051482=positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, 0035071=salivary gland cell autophagic cell death, 0016319=mushroom body development, 0007629=flight behavior" "0016020=membrane, 0005789=endoplasmic reticulum membrane, 0005783=endoplasmic reticulum" "inositol 1,4,5-trisphosphate (InsP3 ) receptor, inositol-1,4,5-trisphosphate receptor, inositol-1,3,5,-trisphosphate receptor, dip, l(3)05616, 1, 4, 5-inositol trisphosphate receptor, l(3)itpr, DmInsP[[3R]], IP[[3]]R, Type 1 InsP{3} receptor, itpr, Itpr, dIP[[3]]R, dm_IP3 receptor, Itp-r[1], unnamed, inositol triphosphate receptor 1, Itp-r-83A, ITP-r83A, inositol 1,4,5-trisphosphate receptor, InsP[[3]]R, Insp3R, anon-WO02059370.49, IP[[3]] receptor, itpr-83, DmInsP[[3]]R, InsP[[3]], Itp-r, inositol trisphosphate receptor, Inositol(1,4,5)-triphosphate receptor 42B, ITPR1, IP, Ip3R, IP3 receptor, l(3)j5B4, ip3-receptor, Ins3PR, CG1063, Ins(1,4,5)P[[3]] receptor, Itp-r42B, IP3R, InsP[[3]] receptor, Inositol 1,4,5-trisphosphate receptor, inositol 1,4,5-triphosphate receptor, DIP" "IPR014821=Inositol 1,4,5-trisphosphate/ryanodine receptor, IPR000493=Inositol 1,4,5-trisphosphate-binding protein receptor, IPR016093=MIR motif, IPR005821=Ion transport domain, IPR013662=RyR/IP3R Homology associated domain, IPR000699=RIH (RyR and IP3R Homology) domain, IPR015925=Ryanodine receptor-related" CG1063 16-Dec-15 2015_12 ENSDARG00000014655(itpr1a) WBGene00002173(itr-1) ENSXETG00000005153(ITPR1) "ENSMUSG00000030102(Itpr1),ENSMUSG00000030287(Itpr2),ENSMUSG00000042644(Itpr3)" "ENSG00000150995(ITPR1),ENSG00000123104(ITPR2),ENSG00000096433(ITPR3)" " embryonic stage | stage 14 , adult stage , embryonic stage | stage 15 , embryonic stage , embryonic stage | stage 13 , embryonic stage | early " " labral segment

, eye

, head | anterior

, labial organ

, epidermis | lateral

, adult brain

, leg

, antenna

" " adult stage , larval stage | third instar , embryonic stage | stage 13 , pupal stage , embryonic stage | stage 9 , pupal stage | late , embryonic stage | stage >=9 " " antennal segment 3 sensillum

, photoreceptor cell

, ring gland

, antennal segment 2 sensillum

, somatic mesoderm

, dorsal medial muscle

, myoblast &&of ventral thoracic disc

, morphogenetic furrow | posterior to

, pigment cell

, eye disc

, olfactory sensory organ

, antenna

, mesoderm

, second antennal segment muscle

, embryonic/larval salivary gland

, pharyngeal muscle

, maxillary palp sense organ

, cone cell

, myoblast

, proboscis

, head mesoderm

, myoblast &&of dorsal mesothoracic disc

, cardioblast

, adult brain

, visceral mesoderm

, myoblast &&of imaginal disc

" "feeding behavior defective,lethal - all die before end of larval stage,some die during larval stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,lethal,viable,chemical resistant,dominant,wild-type,cold sensitive,flightless,fertile,poor,starvation stress response defective,large body,gravitaxis defective,visible,neurophysiology defective,partially,flight defective,body size defective,maternal effect,body color defective,neuroanatomy defective,partially lethal - majority die,some die during P-stage,some die during third instar larval stage" "interommatidial bristle,somatic clone,eye photoreceptor cell,rhabdomere,wing,indirect flight muscle,dorsal medial muscle,wing margin,embryonic/larval fat body,midgut primordium,maternal effect,principal midgut epithelial cell,embryonic/larval salivary gland,imaginal disc,neuroblast,ommatidium,mesothoracic tergum,adult mushroom body,antennal lobe" FBgn0000575 emc extra macrochaetae http://flybase.net/reports/FBgn0000575.html "FBgn0010839, FBgn0010869, FBgn0011251, FBgn0011371, FBgn0013464" protein_coding_gene "0001191=RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, 0046982=protein heterodimerization activity, 0003714=transcription corepressor activity" "0042675=compound eye cone cell differentiation, 0046552=photoreceptor cell fate commitment, 0007458=progression of morphogenetic furrow involved in compound eye morphogenesis, 0007460=R8 cell fate commitment, 0008407=chaeta morphogenesis, 0007530=sex determination, 0048854=brain morphogenesis, 0008586=imaginal disc-derived wing vein morphogenesis, 0045466=R7 cell differentiation, 0043392=negative regulation of DNA binding, 0007541=sex determination, primary response to X:A ratio, 0007476=imaginal disc-derived wing morphogenesis, 0002121=inter-male aggressive behavior, 0046331=lateral inhibition, 0008283=cell proliferation, 0007391=dorsal closure, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007494=midgut development, 0008258=head involution, 0045892=negative regulation of transcription, DNA-templated, 0030381=chorion-containing eggshell pattern formation, 0046843=dorsal appendage formation, 0007286=spermatid development, 0007422=peripheral nervous system development, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 0048056=R3/R4 cell differentiation" "0005634=nucleus, 0005737=cytoplasm, 0005654=nucleoplasm" "extramacrochaetae, extra macrochaete, bHLHb28, l(3)61Da, l(3)05592, extramachrochaetae, l(3)04322, Dm0688, golovan, Emc, Extra Macrocheatae, ms(3)61CD, Extramacrochaetae, male sterile(3)61CD, l(3)j4E11, 0094/26, 0587/01, Ach, Extramacrocheate, CG1007, extramacrochaete, Achetous, Extramacrochaete, 0977/09, gov, 0203/10" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain, IPR026052=DNA-binding protein inhibitor" CG1007 16-Dec-15 2015_12 " embryonic stage | stage 5-9 , embryonic stage | stage 13-15 , embryonic stage | stage 8 , larval stage | third instar , embryonic stage | stage 7 , embryonic stage | stage 15 , embryonic stage | stage 8-10 , embryonic stage | stage 11-13 , embryonic stage | stage 6 , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage -- adult stage , embryonic stage | stage 6,7 , egg stage | unfertilized egg , embryonic stage | stage 13 , embryonic stage " " embryonic/larval hindgut

, visceral mesoderm

, mesoderm

,

ubiquitous , anterior midgut proper primordium

, central nervous system

, posterior midgut proper primordium

, embryonic/larval foregut

, cephalic furrow

, embryonic optic lobe primordium

, Malpighian tubule

, inclusive hindgut primordium

, anterior embryonic/larval midgut

,

stripes , tracheal pit

, posterior embryonic/larval midgut

, amnioserosa

, amnioproctodeal invagination

, tracheal pit | presumptive

, posterior transverse furrow

, epidermis | segmentally repeated

, unfertilized egg

, proctodeum

, ventral nerve cord

, apodeme

, ventral furrow

, procephalic segment

,

10% egg length , ectoderm | dorsal

, Malpighian tubule primordium

, ventral midline | restricted

, supraesophageal ganglion

, dorsal mesothoracic disc | restricted

, stomodeum

, imaginal disc

, anterior transverse furrow

" "visible,viable,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,male sterile,recessive,stress response defective,behavior defective,partially lethal - majority die,dominant,cell lethalcell lethal,somatic clone,decreased cell number,some die during pupal stage" "sense organ,ectopic,macrochaeta & thorax,dorsal appendage,chorion,egg chamber,interommatidial bristle,somatic clone,macrochaeta,supernumerary,microchaeta & mesothoracic tergum | supernumerary,embryonic/larval midgut primordium,embryonic head,dorsal fold,embryonic dorsal epidermis,microchaeta,posterior scutellar bristle,sensory mother cell,wing,dorsocentral bristle,scutellar bristle,scutellum & microchaeta-537.4,tormogen cell,eye,polar follicle cell,anterior,oocyte,eye disc,eye disc anterior to the morphogenetic furrow,photoreceptor cell R2,photoreceptor cell R8,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,leg disc anterior compartment,external sensory organ precursor cell,leg sensillum,postvertical bristle,ocellar bristle,wing vein L5,filzkorper,denticle belt,denticle row 1 & abdominal 1 ventral denticle belt,denticle row 1 & abdominal 2 ventral denticle belt,denticle row 1 & abdominal 3 ventral denticle belt,denticle row 1 & abdominal 4 ventral denticle belt,denticle row 1 & abdominal 5 ventral denticle belt,denticle row 1 & abdominal 6 ventral denticle belt,denticle row 1 & abdominal 7 ventral denticle belt,denticle row 2 & abdominal 1 ventral denticle belt,denticle row 2 & abdominal 2 ventral denticle belt,denticle row 2 & abdominal 3 ventral denticle belt,denticle row 2 & abdominal 4 ventral denticle belt,denticle row 2 & abdominal 5 ventral denticle belt,denticle row 2 & abdominal 6 ventral denticle belt,denticle row 2 & abdominal 7 ventral denticle belt,axon | embryonic stage,longitudinal connective,external sensory organ,Malpighian tubule,Malpighian tubule tip cell,embryonic/larval somatic muscle,midgut constriction 1,midgut constriction 2,midgut constriction 3,visceral mesoderm,endoderm,mesothoracic tergum,cephalopharyngeal skeleton,mesothoracic tergum & macrochaeta,embryonic/larval midgut,morphogenetic furrow,cone cell,photoreceptor cell R7,photoreceptor cell R1,photoreceptor cell R6,ommatidium,neuron,wing vein,leg,haltere,segment,antennal segment 3 sensillum,chaeta" FBgn0013759 CASK CASK ortholog http://flybase.net/reports/FBgn0013759.html "FBgn0015923, FBgn0038904, FBgn0043003" protein_coding_gene "0005524=ATP binding, 0004683=calmodulin-dependent protein kinase activity, 0005515=protein binding, 0004674=protein serine/threonine kinase activity" "0007163=establishment or maintenance of cell polarity, 0007298=border follicle cell migration, 0007628=adult walking behavior, 0008582=regulation of synaptic growth at neuromuscular junction, 0046331=lateral inhibition, 0008049=male courtship behavior, 0046928=regulation of neurotransmitter secretion, 0016081=synaptic vesicle docking, 0007155=cell adhesion, 2000331=regulation of terminal button organization, 0072375=medium-term memory, 1900244=positive regulation of synaptic vesicle endocytosis, 0007616=long-term memory, 0007615=anesthesia-resistant memory, 0016080=synaptic vesicle targeting, 0007269=neurotransmitter secretion, 1900073=regulation of neuromuscular synaptic transmission, 0006468=protein phosphorylation, 0040012=regulation of locomotion, 0008344=adult locomotory behavior, 0008360=regulation of cell shape" 0005954=calcium- and calmodulin-dependent protein kinase complex "CAKI, RE09582p, CG13413, Caki, CASK, Cask, Cmg, cask, Camguk, Calcium/calmodulin-dependent protein kinase, CamguK, CamGUK, CAMGUK, DLin-2, cmg, dCASK, CG13412, camguk, caki, Camguk/CASK adaptor protein, calmodulin-dependent kinase, CMG/CASK, CG6703, CMG" "IPR014775=L27 domain, C-terminal, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR008144=Guanylate kinase-like domain, IPR004172=L27 domain, IPR000719=Protein kinase domain, IPR020590=Guanylate kinase, conserved site, IPR011009=Protein kinase-like domain, IPR001452=SH3 domain, IPR001478=PDZ domain, IPR011511=Variant SH3 domain, IPR008145=Guanylate kinase/L-type calcium channel beta subunit, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6703 16-Dec-15 2015_12 ENSDARG00000059809(cask) WBGene00002991(lin-2) ENSXETG00000004852(cask) ENSMUSG00000031012(Cask) ENSG00000147044(CASK) " adult stage && oogenesis stage | stage S10B , embryonic stage | stage 11 , embryonic stage | stage 14 , embryonic stage | stage 8-12 , pupal stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage , adult stage , embryonic stage | stage >=9 , embryonic stage | 8-24 hr , larval stage , embryonic stage " " polar follicle cell

, neuroblast

, Malpighian tubule

, embryonic/larval hindgut

, anterior midgut proper primordium

, central nervous system

, posterior midgut proper primordium

, ovary

, nurse cell

, adult head

, embryonic central nervous system | presumptive | restricted

, larval central nervous system

" adult stage " lobula

, adult brain

, lobula plate

, optic lobe

, lamina

, medulla neuropil

" "fertile,courtship behavior defective,male,locomotor behavior defective,recessive,dominant,neuroanatomy defective,learning defective,memory defective,neurophysiology defective,flight defective,visual behavior defective,viable,visible" "type Ib terminal bouton | third instar larval stage,type Is terminal bouton | third instar larval stage,type Ib terminal bouton | third instar larval stageVGlut-OK371,type Ib terminal bouton | third instar larval stageMef2.PR,synaptic vesicle,embryonic/larval neuromuscular junction,bouton,chaeta,trichogen cell,border follicle cell" FBgn0041096 rols rolling pebbles http://flybase.net/reports/FBgn0041096.html "FBgn0010928, FBgn0011323, FBgn0036241, FBgn0036243, FBgn0036244, FBgn0052096, FBgn0063612, FBgn0063798" protein_coding_gene "0005515=protein binding, 0008270=zinc ion binding, 0050839=cell adhesion molecule binding, 0008307=structural constituent of muscle" "0007298=border follicle cell migration, 0061327=anterior Malpighian tubule development, 0045214=sarcomere organization, 0007520=myoblast fusion" "0005737=cytoplasm, 0009986=cell surface, 0030018=Z disc, 0005912=adherens junction" "Rol/Ants, antisocial, CG12277, CG17155, Antisocial, Rols7, Rolling pebbles, ANTS, ants/rols, l(3)08232, ants, l(3)68Fd, anon-WO0257455.19, l(3)j2A6, rols\ants, rolling pebbles 7, Ants, Rols6, CG5679, CG32096, Rols" "IPR011990=Tetratricopeptide-like helical domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR020683=Ankyrin repeat-containing domain, IPR002110=Ankyrin repeat, IPR013026=Tetratricopeptide repeat-containing domain, IPR001841=Zinc finger, RING-type" CG32096 16-Dec-15 2015_12 "ENSXETG00000005328(TANC2),ENSXETG00000007592(TANC1)" "ENSMUSG00000053580(Tanc2),ENSMUSG00000035168(Tanc1)" "ENSG00000115183(TANC1),ENSG00000170921(TANC2)" " embryonic stage | stage 15 , embryonic stage | stage 12-15 , embryonic stage | stage > 12 , embryonic stage | stage 11 , embryonic stage | stage 11-14 " " muscle attachment site

, myotube

, endoderm

, embryonic muscle system && myoblast | subset

, embryonic muscle system | restricted

" " embryonic stage | stage 11-14 , embryonic stage | stage 15 , embryonic stage | stage 11 , embryonic stage | stage 12-15 " " embryonic muscle system | restricted

, muscle attachment site

, embryonic muscle system && myoblast | subset

, myotube

" "partially lethal - majority live,fertile,viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" "Malpighian tubule main body primordium,embryonic Malpighian tubule,embryonic anterior Malpighian tubule,dorsal acute muscle & myotube,embryonic myoblast,embryonic somatic muscle,embryonic/larval pharynx,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,presumptive embryonic/larval digestive system,muscle fiber,midgut constriction 1,border follicle cell,somatic clone" DRSC09873 IE -1.981272366 -1.159407617 -1.844324834 2.221281031 0.538576568 0.883104833 FBgn0000439 Dfd Deformed http://flybase.net/reports/FBgn0000439.html protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0033613=activating transcription factor binding, 0001158=enhancer sequence-specific DNA binding" "1990403=embryonic brain development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035289=posterior head segmentation, 1902339=positive regulation of apoptotic process involved in morphogenesis, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0010468=regulation of gene expression, 0007380=specification of segmental identity, head, 0060323=head morphogenesis, 0060322=head development" 0005634=nucleus "DFD, deformed, CG2189, dfd, l(3)84Ae, BG:DS00276.5, EbR11, DmDfd" "IPR020479=Homeodomain, metazoa, IPR001827=Homeobox protein, antennapedia type, conserved site, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR017995=Homeobox protein, antennapedia type, IPR001356=Homeobox domain" CG2189 16-Dec-15 2015_12 "ENSDARG00000059276(hoxd4a),ENSDARG00000013533(hoxb4a),ENSDARG00000070338(hoxc4a),ENSDARG00000070308,ENSDARG00000057724(hoxa4a)" WBGene00011069(R06F6.6) "ENSMUSG00000000942(Hoxa4),ENSMUSG00000038692(Hoxb4),ENSMUSG00000042464(Hoxd4),ENSMUSG00000075394(Hoxc4)" "ENSG00000198353(HOXC4),ENSG00000182742(HOXB4),ENSG00000170166(HOXD4)" " embryonic stage , larval stage , embryonic stage | stage 5-9 , embryonic stage | stage 11-17 , embryonic stage | stage 5 " " prothoracic segment | posterior

, labial segment | posterior

{ + Scr*, tsh- } , larval central nervous system

, parasegment 1

, maxillary palpus | primordium

, embryonic central nervous system | restricted

, embryonic maxillary segment

, embryonic mandibular segment

, eye-antennal disc

, organism | 60-80% egg length

, parasegment 1 | anterior to

, peripodial epithelium

" " embryonic stage | stage 13 , embryonic stage , embryonic stage | stage 6 , embryonic stage | stage 7 , embryonic stage | cellular blastoderm , embryonic stage | stage >=11 , embryonic stage | stage 8 " " dorsal ridge | anterior

, parasegment 1

, cephalic furrow

, maxillary segment

, mandibular segment | ventral

, ectoderm | restricted

, mandibular segment

, ventral midline

, hypopharyngeal lobe

, maxillary segment | ventral

" "some die during embryonic stage,recessive,visible,dominant,viable,lethal,heat sensitive,poor,polyphasic,partially lethal - majority die,lethal - all die before end of embryonic stage,decreased cell death,cell shape defective,increased cell death" "head bristle,ectopic,adult head,maxillary palpus,eye,ocellus,subesophageal ganglion,heat sensitive,thoracico-abdominal ganglion,adult salivary gland,lateral process,pharyngeal bars,labial segment,prothoracic segment,mesothoracic segment,metathoracic segment,external sensory organ,labial disc,embryonic/larval labial organ,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,mouth hooks,cirri,proboscis muscle 1,embryonic maxillary segment,embryonic mandibular segment,mandibular neuromere,hypostomal sclerite,dental sclerite,terminal organ,ventral organ,embryonic head,cephalopharyngeal skeleton,posterior,embryonic tritocerebrum,ectopic | embryonic stage,embryonic thoracic segment & embryonic/first instar larval cuticleprd.RG1,abdominal segment & embryonic/first instar larval cuticleprd.RG1,abdominal lateral monoscolopidial chordotonal organ lch1 | embryonic stage,abdominal ventral monoscolopidial chordotonal organ vch1 | embryonic stage,dorsal group sensillum | embryonic stage,intersegmental nerve,segmental nerve,presumptive embryonic/larval tracheal system,dorsal ridge,embryonic/larval oenocyte precursor,embryonic gastric caecum & parasegment 3how-24B,embryonic head segment,embryonic abdominal segment,embryonic labial segment,embryonic thoracic segment,third segment of antenna,antennal disc,arista,pretarsus,embryonic segment,embryonic/first instar larval cuticle,denticle" FBgn0024245 dnt doughnut on 2 http://flybase.net/reports/FBgn0024245.html protein_coding_gene "0004713=protein tyrosine kinase activity, 0046982=protein heterodimerization activity, 0005524=ATP binding" "0007435=salivary gland morphogenesis, 0007411=axon guidance, 0046331=lateral inhibition, 0006468=protein phosphorylation, 0016204=determination of muscle attachment site, 0016203=muscle attachment, 0007165=signal transduction" "0016021=integral component of membrane, 0043235=receptor complex, 0005886=plasma membrane" "doughnut, CG17559, DNT, Doughnut, Doughnut on 2" "IPR000719=Protein kinase domain, IPR003306=WIF domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR011009=Protein kinase-like domain, IPR008266=Tyrosine-protein kinase, active site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain" CG17559 16-Dec-15 2015_12 ENSDARG00000007231(zgc:158381) WBGene00003007(lin-18) ENSXETG00000011818(RYK) ENSMUSG00000032547(Ryk) ENSG00000163785(RYK) " embryonic stage--larval stage , embryonic stage | blastoderm , embryonic stage | gastrula , embryonic stage | late , embryonic stage | stage >= 5 , embryonic stage | stage 11 , embryonic stage | extended germ band , embryonic stage | stage 6-12 " "

20-80% egg length , cephalic furrow

, imaginal precursor

, amnioproctodeal invagination

, organism | striped

, embryonic/larval tracheal pit | surrounding

,organism | stripes

, ventral furrow

" "viable,visible,partially lethal - majority die,some die during pupal stage" "presumptive embryonic salivary gland,embryonic/larval salivary gland,lateral transverse muscle,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0003068 per period http://flybase.net/reports/FBgn0003068.html "FBgn0000321, FBgn0020918" protein_coding_gene "0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0005515=protein binding, 0003714=transcription corepressor activity, 0003712=transcription cofactor activity, 0042803=protein homodimerization activity" "0007620=copulation, 0001306=age-dependent response to oxidative stress, 0043153=entrainment of circadian clock by photoperiod, 0045892=negative regulation of transcription, DNA-templated, 0009649=entrainment of circadian clock, 0009416=response to light stimulus, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0042745=circadian sleep/wake cycle, 0009266=response to temperature stimulus, 0006979=response to oxidative stress, 0001932=regulation of protein phosphorylation, 2000678=negative regulation of transcription regulatory region DNA binding, 0007619=courtship behavior, 0008340=determination of adult lifespan, 0007617=mating behavior, 0042752=regulation of circadian rhythm, 0045433=male courtship behavior, veined wing generated song production, 0007622=rhythmic behavior, 0045475=locomotor rhythm, 0007624=ultradian rhythm, 0045187=regulation of circadian sleep/wake cycle, sleep, 0060086=circadian temperature homeostasis, 0048512=circadian behavior, 0007616=long-term memory, 0008062=eclosion rhythm, 0048148=behavioral response to cocaine, 0007623=circadian rhythm, 1904059=regulation of locomotor rhythm" "0005737=cytoplasm, 0005634=nucleus" "PER, mel_per, clk-6, Clk, Per, Clock, dperiod, per, PERIOD, period, CG2647, dper, clock-6, dmper, EG:155E2.4, dPER, period clock protein, Period" "IPR013767=PAS fold, IPR000014=PAS domain, IPR001610=PAC motif" CG2647 16-Dec-15 2015_12 "ENSDARG00000034503(per2),ENSDARG00000012499(per1b),ENSDARG00000056885(per1a),ENSDARG00000010519(per3),ENSDARG00000070143" "ENSXETG00000008256(PER2),ENSXETG00000009086(PER1),ENSXETG00000005028(PER3)" "ENSMUSG00000020893(Per1),ENSMUSG00000055866(Per2),ENSMUSG00000028957(Per3)" "ENSG00000179094(PER1),ENSG00000132326(PER2),ENSG00000049246(PER3)" adult stage " adult lateral neuron

, adult head

, photoreceptor cell

, adult brain | restricted

" adult stage " lamina neuropil

, supraesophageal ganglion

, neuropil

, optic lobe

, optic chiasma

, photoreceptor cell

, ocellus

" "locomotor rhythm defective,eclosion rhythm defective,song defective,recessive,circadian rhythm defective,neuroanatomy defective,semi-sterile,conditional,semi-fertile,sleep defective,behavior defective,visual behavior defective,wild-type,circadian behavior defective,male,mating rhythm defective,male limited,heat sensitive,memory defective,courtship behavior defective,semidominant,cold sensitive,mating defective,viable,photoperiod response variant,stress response defective,gravitaxis defective,aging defective,visible,body color defective" "Malpighian tubule,indirect flight muscle motor neuron MN5,posterior adult hindgut,pericardial cell,trichogen cell,mesothoracic tergum" FBgn0260632 dl dorsal http://flybase.net/reports/FBgn0260632.html "FBgn0000462, FBgn0025325, FBgn0260285" protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0070491=repressing transcription factor binding, 0070379=high mobility group box 1 binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0005515=protein binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding, 0016015=morphogen activity" "0045892=negative regulation of transcription, DNA-templated, 0048935=peripheral nervous system neuron development, 0007498=mesoderm development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0006355=regulation of transcription, DNA-templated, 0009952=anterior/posterior pattern specification, 0010629=negative regulation of gene expression, 0010004=gastrulation involving germ band extension, 0007507=heart development, 0007501=mesodermal cell fate specification, 0009950=dorsal/ventral axis specification, 0042387=plasmatocyte differentiation, 0008063=Toll signaling pathway, 0035006=melanization defense response, 0007398=ectoderm development, 0006964=positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, 0008354=germ cell migration, 0045893=positive regulation of transcription, DNA-templated, 0001715=ectodermal cell fate specification, 0007419=ventral cord development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007369=gastrulation, 0006955=immune response, 0008358=maternal determination of anterior/posterior axis, embryo, 0009953=dorsal/ventral pattern formation, 0035206=regulation of hemocyte proliferation, 0006952=defense response, 0000381=regulation of alternative mRNA splicing, via spliceosome" "0005634=nucleus, 0005737=cytoplasm, 0031594=neuromuscular junction" "GSd447, CG6667, NFkappabeta, NFkappaB, Dl, anon-EST:GressD7, mat(2)dorsal, Dorsal, fs(2)k10816, dL, DL, REL, d;, Embryonic polarity protein dorsal, Dor" "IPR013783=Immunoglobulin-like fold, IPR011539=Rel homology domain (RHD), DNA-binding domain, IPR011363=Dorsal/Dif protein, IPR002909=IPT domain, IPR030492=Rel homology domain, conserved site, IPR008967=p53-like transcription factor, DNA-binding, IPR000451=NF-kappa-B/Dorsal, IPR014756=Immunoglobulin E-set" CG6667 16-Dec-15 2015_12 "ENSXETG00000002209(REL),ENSXETG00000026173(Q6NVN7_XENTR)" ENSMUSG00000002983(Relb) ENSG00000104856(RELB) " embryonic stage | 0-2.5 hr , larval stage , embryonic stage | >=6hr , adult stage | male , adult stage && oogenesis stage , embryonic stage | , ovary

,

ubiquitous " " embryonic stage | stage 2-3 , embryonic stage | stage 3-9 , embryonic stage | stage 3-7 , embryonic stage | stage 2 , embryonic stage | stage 1-17 , adult stage && oogenesis stage | stage S9-12 , embryonic stage | stage 7-14 , embryonic stage | stage 2-4 , adult stage , embryonic stage | stage 3-5 , embryonic stage | stage 7 , egg stage | unfertilized egg " " organism | ubiquitous

, organism | dorsal ventral gradient

,

ubiquitous , nurse cell

, ventral furrow

, ovary

, mesoderm

, unfertilized egg

" FBgn0036107 CG7949 http://flybase.net/reports/FBgn0036107.html protein_coding_gene IPR002744=Domain of unknown function DUF59 CG7949 16-Dec-15 2015_12 ENSDARG00000052010(zgc:92345) YHR122W() WBGene00009736(F45G2.10) ENSXETG00000022111(Q5HZC8_XENTR) ENSMUSG00000031879(Fam96b) ENSG00000166595(FAM96B) viable FBgn0010607 l(2)05714 lethal (2) 05714 http://flybase.net/reports/FBgn0010607.html FBgn0031658 protein_coding_gene "CG8886, l(2)05715" CG8886 16-Dec-15 2015_12 "lethal,recessive,viable,visible" mesothoracic tergum FBgn0003345 sd scalloped http://flybase.net/reports/FBgn0003345.html "FBgn0025967, FBgn0026840, FBgn0027221, FBgn0027225, FBgn0027247, FBgn0027258, FBgn0040146, FBgn0062702" protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0019904=protein domain specific binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0008134=transcription factor binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0044212=transcription regulatory region DNA binding" "0035331=negative regulation of hippo signaling, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0001745=compound eye morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 2000826=regulation of heart morphogenesis, 0055013=cardiac muscle cell development, 0007476=imaginal disc-derived wing morphogenesis, 0007423=sensory organ development, 0060429=epithelium development, 0007293=germarium-derived egg chamber formation, 0035220=wing disc development, 0007399=nervous system development, 0007480=imaginal disc-derived leg morphogenesis, 0007525=somatic muscle development, 0072089=stem cell proliferation" 0005634=nucleus "Scalloped, l(1)G0262, l(1)G0315, DROEXO2, EP(X)1088, l(1)G0483, SD, CG8544, l(1)HF394, anon-EST:Liang-2.14, clone 2.14, spatula, EP1088, l(1)III, Sd, l(1)G0239, DROEXO, l(1)G0309, sp, TEAD" IPR000818=TEA/ATTS CG8544 16-Dec-15 2015_12 "ENSDARG00000028159(tead1a),ENSDARG00000059483(LOC100006454),ENSDARG00000063649(zgc:171784)" WBGene00001208(egl-44) ENSXETG00000003395(TEAD2) "ENSMUSG00000030353(Tead4),ENSMUSG00000055320(Tead1),ENSMUSG00000002249(Tead3),ENSMUSG00000030796(Tead2)" "ENSG00000197905(TEAD4),ENSG00000187079(TEAD1),ENSG00000007866(TEAD3),ENSG00000074219(TEAD2)" " larval stage , adult stage , embryonic stage , embryonic stage | >= stage 9 , embryonic stage | >= stage 11 " " anepisternum | precursor

, photoreceptor cell

, perineurial sheath cell

, larval labral segment sense organ

, maxillary palp sense organ

, calyx of mushroom body

, subesophageal ganglion | restricted

, central nervous system

, scutellum | precursor

, microchaeta

, subesophageal ganglion

, sense organ

, sacculus

, peripheral nervous system

, mesothoracic extracoxal depressor muscle 66

, eye-antennal disc

, protocerebrum

, supraesophageal ganglion

, dorsal mesothoracic disc

, antennal sense organ

" "visible,viable,lethal,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,stress response defective,dominant,fertile,chemosensitive behavior defective,taste perception defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,wild-type,mitotic cell cycle defective,somatic clone,developmental rate defective,neuroanatomy defective,male fertile,female fertile,male sterile,increased cell death,partially lethal - majority die,size defective,decreased cell number,lethal - all die during pupal stage" "eye,wing disc,wing,wing pouch,somatic clone,midgut constriction,A1-7 lateral longitudinal muscle 1,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,embryonic/larval cardial cell,heat sensitive,macrochaeta,posterior wing margin,chaeta,scutellum,adult thorax,ectopic,microchaeta,wing vein,anterior,wing margin,capitellum,wing sensillum,scutellar bristle,haltere,macrochaeta & wing,wing blade,wing vein & macrochaeta,head,crossvein,wing hinge,posterior scutellar bristle,wing & macrochaeta,interommatidial bristle,leg,unguis,indirect flight muscle,metathoracic laterotergite,segmental nerve,wing vein L5,ommatidium,ventral thoracic disc,adult,pupa,A1-7 dorsal acute muscle 1,somatic muscle,wing vein L2,wing vein L4,adult head,lobula plate,lamina,mesothoracic tergum,eye disc | third instar larval stage,epithelium,egg chamber" DRSC20370 K 0.051011668 0.12632254 -0.754168718 1.473546613 1.980753536 0.793557353 FBgn0002522 lab labial http://flybase.net/reports/FBgn0002522.html FBgn0010742 protein_coding_gene "0043565=sequence-specific DNA binding, 0035326=enhancer binding, 0003700=sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0001709=cell fate determination, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035284=brain segmentation, 0006357=regulation of transcription from RNA polymerase II promoter, 0060323=head morphogenesis, 0090098=positive regulation of decapentaplegic signaling pathway, 0007494=midgut development, 0030154=cell differentiation, 0007420=brain development" 0005634=nucleus "lb, l(3)01241, F90-2, BG:DS00004.9, F24, l(3)84Ac, EfR9, Labial, CG1264, F121, F90, LAB, Dm lab, Lab, Dmlab, DmLab" "IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG1264 16-Dec-15 2015_12 ENSDARG00000057721(hoxa1a) WBGene00000436(ceh-12) ENSXETG00000000715(hoxa1) " embryonic stage | stage 9-11 , embryonic stage | >=2-4 hr , embryonic stage , embryonic stage | 0-24 hr , embryonic stage | 2-24 hr , embryonic stage | extended germ band , embryonic stage | contracted germ band , larval stage && pupal stage , embryonic stage && larval stage && pupal stage , embryonic stage | 12-14 hr " " cephalic furrow | anterior to

, mesothoracic segment | dorsal

{ + Antp*, BX-C- } , parasegment 4,5

{ + Antp* } , mesothoracic segment | dorsal

{ + Scr*, Antp*, BX-C- } , prothoracic segment | posterior <&> dorsal

{ 0 BX-C- } , metathoracic segment | dorsal

{ + Scr*, Antp*, BX-C- } , posterior midgut proper primordium

, metathoracic segment | dorsal

{ + Antp*, BX-C- } , parasegment 4..13 midline

{ + tsh-, Antp* } , prothoracic segment | dorsal

{ + Scr*, Antp*, BX-C- } , abdominal segment 1--8

, prothoracic segment | dorsal

{ + Antp*, BX-C- } , hypopharyngeal lobe | anlagen

, central nervous system

, embryonic mandibular segment

, parasegment 4..13 tracheal placode

{ + tsh- } ,

{ + Antp*, BX-C- } , embryonic procephalic segment | anlagen

, embryonic/larval midgut

, abdominal segment 1..8 | dorsal

{ + Scr*, Antp*, BX-C- } " " embryonic stage | stage 9-11 , embryonic stage | stage 12 , embryonic stage | mid-late , embryonic stage | stage 13-17 , embryonic stage , embryonic stage , embryonic stage | stage 13-14 " " ectoderm && intercalary segment

, embryonic/larval midgut | restricted

, deuterocerebral neuroblast | subset

, endoderm

{ + abd-AM1 } , parasegment 7 endoderm

{ + Ubxhs.PU } , embryonic central nervous system | restricted

, endoderm &&of parasegment 7--12

, midgut

, anterior midgut proper primordium

, midgut

{ - dpps4 } , endoderm | anterior

, parasegment 1..7 midgut

{ + Ubx* } , larval sense organ | precursor

, dorsal ridge

, posterior midgut proper primordium

, embryonic/larval midgut

{ - Ubx* } , parasegment 8..12 midgut

{ v wgx* } , procephalic segment | restricted

, midgut

{ + Pc* } , tritocerebral neuroblast

" "viable,fertile,lethal,recessive,wild-type,visible,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "crystal cell,embryonic head,embryonic/larval salivary gland,arista,cuprophilic cell,midgut interstitial cell,cephalopharyngeal skeleton,tritocerebral neuromere,tritocerebral commissure,longitudinal connective,postorbital bristle,supernumerary,adult midgut,embryonic/larval midgut,embryonic brain,temperature conditional,mouth hooks,tritocerebrum,embryonic tritocerebrum,embryonic/larval tritocerebrum,embryonic/larval tritocerebral commissure,frontal connective,wing vein,wing margin" DRSC12627 K -0.529910814 -0.564672322 -0.411196595 0.097667134 1.571932762 1.455156612 FBgn0260799 p120ctn Adherens junction protein p120 http://flybase.net/reports/FBgn0260799.html "FBgn0015587, FBan0017484, FBgn0032995, FBgn0041583" protein_coding_gene 0045296=cadherin binding "0010172=embryonic body morphogenesis, 0034334=adherens junction maintenance, 0016337=single organismal cell-cell adhesion, 0032956=regulation of actin cytoskeleton organization, 0001745=compound eye morphogenesis, 0007155=cell adhesion, 0060997=dendritic spine morphogenesis" "0005737=cytoplasm, 0005813=centrosome, 0005913=cell-cell adherens junction, 0005912=adherens junction" "P120ctn, p120catenin, p120-catenin, dp120ctn, Adherens-junction-protein-p120, Dp120ctn, p120, p120[ctn], P120-catenin, Dp120[ctn], P120-Catenin, CG17484, dP120ctn, p120 catenin, P120" "IPR000225=Armadillo, IPR028435=Plakophilin/Delta catenin, IPR011989=Armadillo-like helical, IPR016024=Armadillo-type fold, IPR028446=Juxtamembrane domain-associated catenin" CG17484 16-Dec-15 2015_12 ENSDARG00000003779(ctnnd2b) "ENSXETG00000006316(ARVCF),ENSXETG00000007089(CTNND1),ENSXETG00000010376(PK4P)" "ENSMUSG00000000325(Arvcf),ENSMUSG00000034101(Ctnnd1),ENSMUSG00000022240(Ctnnd2),ENSMUSG00000026991(Pkp4)" "ENSG00000099889(ARVCF),ENSG00000198561(CTNND1),ENSG00000169862(CTNND2),ENSG00000144283(PKP4)" embryonic stage " embryonic foregut

,

ubiquitous , anterior embryonic/larval midgut

, midgut constriction

, embryonic hindgut

, posterior embryonic/larval midgut

, embryonic central nervous system

" " larval stage , embryonic stage , oogenesis stage , embryonic stage | stage >9 , embryonic stage && larval stage , embryonic stage | stage 4-9 " " eye disc

, morphogenetic furrow | anterior to

, embryonic sensory system

, neuroblast

, morphogenetic furrow

, larval brain | restricted

, ganglion mother cell

, germline cell

, follicle cell

, embryonic epidermis

, embryonic tracheal system

, embryonic central nervous system | restricted

, neuron

, embryonic peripheral nervous system | restricted

, border follicle cell

, embryonic midgut

" FBgn0259211 grh grainy head http://flybase.net/reports/FBgn0259211.html "FBgn0004586, FBgn0000572, FBgn0001136, FBgn0010628, FBgn0010683, FBgn0013964, FBgn0014968, FBgn0026798, FBgn0050111, FBgn0047195" protein_coding_gene "0042803=protein homodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0043565=sequence-specific DNA binding" "0007399=nervous system development, 0007402=ganglion mother cell fate determination, 0008362=chitin-based embryonic cuticle biosynthetic process, 0007464=R3/R4 cell fate commitment, 0035159=regulation of tube length, open tracheal system, 0061041=regulation of wound healing, 0007428=primary branching, open tracheal system, 0061024=membrane organization, 0007426=tracheal outgrowth, open tracheal system, 0007009=plasma membrane organization, 0040003=chitin-based cuticle development, 0042052=rhabdomere development, 0007424=open tracheal system development, 0003382=epithelial cell morphogenesis, 0006357=regulation of transcription from RNA polymerase II promoter, 0007419=ventral cord development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0035152=regulation of tube architecture, open tracheal system, 0042127=regulation of cell proliferation, 0008360=regulation of cell shape" 0005634=nucleus "BcDNA:LD38807, EG:191D12.1, Grainy head, neuronal transcription factor 1, l(2)06850, Elf-1, Grainyhead, hsk, NTF1, NTF-1/Elf-1, l(2)IM45, CG30111, Gh, GRH, ntf-1, Ntf, CG42311, NTF-1, Neurogenic element binding transcription factor, Grh, head skeleton, elf1, Element I binding activity, Elf1, elf1(CAG)[[7]], CG5058, DREB, NTF, l(2)s2140, decapentaplegic repression element binding protein, Elf-1/NTF-1, ELF1, grainyhead, Ntf1" IPR007604=CP2 transcription factor CG42311 16-Dec-15 2015_12 WBGene00001707(grh-1) "ENSXETG00000003899(grhl3),ENSXETG00000007012(GRHL1),ENSXETG00000006632(tfcp2l3)" embryonic stage " ventral nerve cord

, epidermis

, embryonic brain

" " larval stage , embryonic stage , larval stage | third instar , embryonic stage | stage >=11 " " embryonic/larval hindgut

, embryonic/larval foregut

, imaginal disc

, embryonic/larval anterior spiracle

, dorsal mesothoracic disc

, embryonic/larval trachea

, embryonic/larval proventriculus

, ventral nerve cord | segmentally repeated

, neuroblast

, epidermis

, larval optic lobe

" DRSC05683 I -1.006478044 -4.205843924 -0.990553514 -1.199217732 0.398120497 0.743839703 FBgn0262733 Src64B Src oncogene at 64B http://flybase.net/reports/FBgn0262733.html "FBgn0003501, FBgn0022792, FBgn0035561, FBgn0086537" protein_coding_gene "0004713=protein tyrosine kinase activity, 0005102=receptor binding, 0005524=ATP binding" "0036058=filtration diaphragm assembly, 0007616=long-term memory, 0045886=negative regulation of synaptic growth at neuromuscular junction, 0007435=salivary gland morphogenesis, 0006468=protein phosphorylation, 0007300=ovarian nurse cell to oocyte transport, 0016319=mushroom body development, 0048477=oogenesis, 0090136=epithelial cell-cell adhesion, 0030036=actin cytoskeleton organization, 0007349=cellularization, 0030717=karyosome formation, 0007411=axon guidance, 0008064=regulation of actin polymerization or depolymerization, 0018108=peptidyl-tyrosine phosphorylation, 0045860=positive regulation of protein kinase activity, 0007424=open tracheal system development, 0007254=JNK cascade, 0030046=parallel actin filament bundle assembly, 0007391=dorsal closure, 0008355=olfactory learning, 0030723=ovarian fusome organization, 0030708=germarium-derived female germ-line cyst encapsulation, 0034332=adherens junction organization, 0008302=female germline ring canal formation, actin assembly, 0007293=germarium-derived egg chamber formation, 0008335=female germline ring canal stabilization, 0007301=female germline ring canal formation, 0007611=learning or memory" "0005829=cytosol, 0005886=plasma membrane, 0045172=germline ring canal" "SRC64B, Dm SRC1, Src1, dSrc, Src64, DSRC64, D-Src64B, D-src, DSrc64, Src64b, src1, mRNA-like ncRNA in embryogenesis 5, src64, Dsrc, CG7524, DSrc, c-src, DmHD-358, Src, src64b, MRE5, SRC 64B, Dsrc64, Dsrc64B, dsrc, HD-358, src64B, C-src1, src, DSrc64B, Src proto oncogene sequence" "IPR001452=SH3 domain, IPR000719=Protein kinase domain, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000980=SH2 domain, IPR011009=Protein kinase-like domain, IPR020635=Tyrosine-protein kinase, catalytic domain, IPR008266=Tyrosine-protein kinase, active site" CG7524 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage | female , prepupal stage--pupal stage , oogenesis stage && adult stage | female , embryonic stage " " oocyte

, ovary

" adult stage && oogenesis stage " nurse cell | restricted

, ring canal

" FBgn0005648 Pabp2 Pabp2 http://flybase.net/reports/FBgn0005648.html protein_coding_gene "0008143=poly(A) binding, 0003729=mRNA binding, 0000166=nucleotide binding, 0003723=RNA binding" "0022008=neurogenesis, 0006378=mRNA polyadenylation, 0000289=nuclear-transcribed mRNA poly(A) tail shortening, 0000398=mRNA splicing, via spliceosome" "0071013=catalytic step 2 spliceosome, 0005737=cytoplasm, 0005634=nucleus, 0071011=precatalytic spliceosome" "PABP2, PABPN1, CG2163, nuclear poly(A)-binding protein, pAbp2, dpabII, rox2, polyA-binding protein II, ROX2, Rox2, poly-A binding protein 2, pabp2" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain" CG2163 16-Dec-15 2015_12 ENSDARG00000045373(pabpn1) YIR001C(SGN1) WBGene00003904(pabp-2) ENSXETG00000014597(Q6NVP7_XENTR) ENSMUSG00000022198 ENSG00000100836(PABPN1) " larval stage , embryonic stage | late , embryonic stage -- adult stage , adult stage , pupal stage , larval stage && pupal stage && adult stage " ovary

" larval stage , adult stage | female && oogenesis stage , embryonic stage " " follicle cell

, female germline stem cell

" "partially lethal - majority die,recessive,lethal,female semi-sterile,maternal effect,mitotic cell cycle defective,germline clone,viable,neuroanatomy defective,some die during pupal stage" "chorion,egg chamber,embryo,maternal effect,female germline cell,chorion | germline clone,germline clone,embryonic/larval neuroblast,ganglion mother cell" DRSC07501 IEK 0.090881594 -1.868369048 -0.096971143 -1.736825069 1.681849471 2.510676261 FBgn0011758 B-H1 BarH1 http://flybase.net/reports/FBgn0011758.html protein_coding_gene "0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0008052=sensory organ boundary specification, 0008407=chaeta morphogenesis, 0001751=compound eye photoreceptor cell differentiation, 0008057=eye pigment granule organization, 0007455=eye-antennal disc morphogenesis, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007479=leg disc proximal/distal pattern formation, 0045892=negative regulation of transcription, DNA-templated" 0005634=nucleus "CG5529, bar-h1, Bar-H1, BarHI, Bar H1, Bar, BH1, barh1, barH1, BarH, Barh1, BarH1" "IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG5529 16-Dec-15 2015_12 "ENSDARG00000070129(barhl2),ENSDARG00000019013(barhl1.1),ENSDARG00000035508(barhl1.2)" WBGene00006873(vab-7) "ENSXETG00000023986(BARHL2),ENSXETG00000006257(BARHL1)" "ENSMUSG00000034384(Barhl2),ENSMUSG00000026805(Barhl1)" "ENSG00000143032(BARHL2),ENSG00000125492(BARHL1)" " pupal stage , embryonic stage , embryonic stage -- adult stage " " peripheral nervous system

, thecogen cell

, external sensory organ

, embryonic central nervous system

, neuron

" " larval stage | late -- P | early , embryonic stage " " photoreceptor cell R6 | presumptive

, neuron

, peripheral nervous system

, embryonic central nervous system

, external sensory organ

, thecogen cell

" "lethal,recessive,visible,viable" "tarsal segment 3,tarsal segment 4,pretarsus,ommatidium,sensillum trichodeum,eye photoreceptor cell,eye,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,cone cell,primary pigment cell,posterior cone cell,anterior cone cell,morphogenetic furrow,photoreceptor cell,ventral thoracic disc,tarsal segment 4 & leg sensillumap-md544" FBgn0003285 rst roughest http://flybase.net/reports/FBgn0003285.html "FBgn0001272, FBgn0005381" protein_coding_gene 0030165=PDZ domain binding "0046331=lateral inhibition, 0046666=retinal cell programmed cell death, 0016202=regulation of striated muscle tissue development, 0007409=axonogenesis, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0001745=compound eye morphogenesis, 0048749=compound eye development, 0007520=myoblast fusion, 0046667=compound eye retinal cell programmed cell death" "0005886=plasma membrane, 0016021=integral component of membrane, 0045177=apical part of cell, 0005913=cell-cell adherens junction" "Irregular chiasm C-roughest protein, rst/irrecC, irrecC-rst, IrreC-Rst, IREE-C, irreC, rst-irrecC, IrreC, C-Roughest, IrreC-rst, rst-irreC, Irre-C, CT13684, Roughest, UB883, Irregular-chiasm-C, Irregular chiasmC-roughest, irregular optic chiasma C, CG4125, irregular chiasm C-roughest, Rst, irreC-roughest, IRREC/RST, IrreC/Rst, Irregular optic chiasma C/Roughest, ChiasmC-roughest, IrrecC, irreC-rst, irregular chiasm-C-roughest, Rst/IrreC" "IPR013098=Immunoglobulin I-set, IPR007110=Immunoglobulin-like domain, IPR013162=CD80-like, immunoglobulin C2-set, IPR013783=Immunoglobulin-like fold, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2" CG4125 16-Dec-15 2015_12 "ENSDARG00000019473(kirrel3),ENSDARG00000060939(LOC572369),ENSDARG00000001634(kirrel),ENSDARG00000056998(si:ch211-195h23.2)" WBGene00006365(syg-1) ENSXETG00000001252() "ENSMUSG00000041734(Kirrel),ENSMUSG00000032036(Kirrel3),ENSMUSG00000036915(Kirrel2)" "ENSG00000183853(KIRREL),ENSG00000149571(KIRREL3),ENSG00000126259(KIRREL2)" " embryonic stage | stage 11 , pupal stage , larval stage | third instar " " embryonic labial segment

, embryonic maxillary segment

, secondary pigment cell

, mesoderm | restricted

, lamina

, larval outer optic anlage

, imaginal disc

, embryonic mandibular segment

, eye-antennal disc

, labral segment

, ventral midline

, retina

, medulla | restricted

, tertiary pigment cell

" "visual behavior defective,heat sensitive,visible,recessive,neuroanatomy defective,female sterile,partially lethal - majority die,decreased cell death,female fertile,poor,viable,reduced,small body,male sterile,eye color defective,dominant,cell death defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type" "ommatidium,interommatidial bristle,cone cell,presumptive embryonic/larval muscle system,optic chiasma,ectopic,antennal segment 3 sensillum,sensillum basiconicum of antennal segment 3,antennal disc,eye disc,embryonic somatic muscle,ommatidial precursor cluster,eye,inter-ommatidial cell,supernumerary,primary pigment cell,inter-ommatidial precursor cell,cell-cell junction,adherens junction,anterior vertical bristle,posterior vertical bristle,postvertical bristle,embryonic myoblast,embryonic/larval salivary gland,thorax & microchaeta,photoreceptor cell pigment granule,secondary pigment cell,tertiary pigment cell,optic lobe,embryonic/larval muscle system,embryonic/larval optic lobe,lamina neuropil,sensillum trichodeum of antennal segment 3,sacculus,four cone-cell ommatidial precursor cluster,lamina,lobula,lobula plate,inter-ommatidial precursor cell | P-stage,embryonic/larval garland cell | third instar larval stage,nucleus | supernumerary | third instar larval stagepros.PMG,chaeta,wing margin,wing hair" FBgn0013469 klu klumpfuss http://flybase.net/reports/FBgn0013469.html "FBgn0010931, FBgn0010938" protein_coding_gene "0003676=nucleic acid binding, 0046872=metal ion binding" "0014019=neuroblast development, 0016360=sensory organ precursor cell fate determination, 0030536=larval feeding behavior, 0046672=positive regulation of compound eye retinal cell programmed cell death, 0002052=positive regulation of neuroblast proliferation, 0046580=negative regulation of Ras protein signal transduction, 0006099=tricarboxylic acid cycle, 0097150=neuronal stem cell maintenance, 2000035=regulation of stem cell division, 0022008=neurogenesis" 0005634=nucleus "CG12296, klumphuss, P09036, Klu, l(3)10052, l(3)09036, Klumpfuss" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG12296 16-Dec-15 2015_12 "YPR015C(),YPR013C()" " larval stage | third instar , embryonic stage " " antennal disc | restricted

, eye disc | restricted

, wing vein L1 | presumptive

, tarsal segment | anlagen

, larval optic lobe | restricted

, morphogenetic furrow | posterior to

, dorsal prothoracic disc | restricted

, proneural cluster

, dorsal mesothoracic disc | restricted

, neuroblast

, scutum | presumptive

, scutellum | anlagen

, ventral thoracic disc | restricted

, larval brain | restricted

" " embryonic stage | stage 11 , embryonic stage , embryonic stage | stage >=10 , embryonic stage | stage 10,11 , embryonic stage | stage 9-11 , embryonic stage | early , embryonic stage | stage 16 " " neuroblast NB2-1

, neuroblast GP

, ventral nerve cord | restricted

, neuroblast

, neuroblast NB5-4

, ganglion mother cell GMC4-2b

, neuroblast NB2-5

, embryonic brain | restricted

, epidermis | restricted

, neuroblast NB5-6

, neuroblast NB2-4

, neuroblast NB4-1

, neuroblast NB5-5

, neuroblast NB4-2

, neuroblast NB1-1

, neuroblast NB7-1

, neuroblast NB7-4

, neuroblast NB6-1

, neuroblast NB7-2

, neuroblast NB5-3

, neuroblast NB4-3

, deuterocerebral neuroblast | subset

, embryonic/larval posterior spiracle

, neuroblast NB7-3

, neuroblast NB5-2

, neuroblast NB2-2

, neuroblast NB5-1

, neuroblast NB3-2

, neuroblast NB6-2

, neuroblast NB3-3

, protocerebral neuroblast | subset

, neuroblast NB3-1

, neuroblast NB1-2

, neuroblast NB3-5

, tritocerebral neuroblast | subset

, procephalic segment

, neuroblast NB4-4

" "neuroanatomy defective,somatic clone,visible,viable,feeding behavior defective,lethal,recessive,partially lethal - majority die,small body,increased cell number,tumorigenic,decreased cell size,decreased cell growth,decreased cell death,increased cell death" "rhabdomere R7,type II neuroblast,supernumerary,somatic clone,chaeta,external sensory organ precursor cell,presutural bristle,anterior supraalar bristle,presutural bristle precursor cell,supraalar bristle precursor cell,embryonic/larval neuroblast,anterior sternopleural bristle,macrochaeta,tarsal segment,tarsal segment 3,tarsal segment 4,tibia,pretarsus,ganglion mother cell GMC4-2b,RP2 motor neuron,abdominal 1 dorsal motor neuron,type I neuroblast,wing,ectopic,eye,adult head,interommatidial bristle,adult thorax,salivary gland,ommatidium,heat sensitive,trochanter,femur,metatarsus,distal,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,sex comb,basal cylinder,wing margin bristle,abdominal 2 dorsal motor neuron,abdominal 3 dorsal motor neuron,abdominal 4 dorsal motor neuron,abdominal 5 dorsal motor neuron,abdominal 6 dorsal motor neuron,abdominal 7 dorsal motor neuron,antennal sense organ,subesophageal ganglion neuron,lens,retina,microchaeta,trichome of the posterior wing margin" DRSC11357 K -0.24081982 -0.027254007 -0.117318036 -0.371421181 1.232147288 1.541410538 FBgn0262742 Fas1 Fasciclin 1 http://flybase.net/reports/FBgn0262742.html "FBgn0000634, FBgn0026839, FBgn0086555" protein_coding_gene 0050839=cell adhesion molecule binding "0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007158=neuron cell-cell adhesion, 0016338=calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules, 0008038=neuron recognition, 0007411=axon guidance" 0005886=plasma membrane "fasciclin I, DROFASI, MRE24, Fasciclin I, Fas I, DROFAS, fas I, CG6588, Fasciclin-1, mRNA-like ncRNA in embryogenesis 24, fas1, fas-I, FasI, fasI, gasI, DROFAS1" IPR000782=FAS1 domain CG6588 16-Dec-15 2015_12 " oogenesis stage , embryonic stage | stage <15 , embryonic stage , embryonic stage | stage 9-10 , embryonic stage | 10-13 hr , embryonic stage | stage >11 , larval stage | third instar , larval stage , embryonic stage | stage 12-13 , adult stage , embryonic stage | stage >12 " " epidermis | dorsal

, ventral neurogenic region | segmentally repeated

, neuroblast

segmentally repeated , ventral nerve cord

, gonad

, neuron &&of central nervous system | restricted

, ectoderm

, embryonic peripheral nervous system

" " embryonic stage | stage 14-16 , embryonic stage | stage 13-16 , embryonic stage | stage 12-13 , embryonic stage | stage 12-16 , embryonic stage | >stage 11 , embryonic stage , embryonic stage | 11-14 hr , embryonic stage | >stage 12 , embryonic stage | stage 9-10 , embryonic stage | stage >12 , embryonic stage | stage <15 , embryonic stage | stage 12 " " antennal sense organ

, RP1 neuron

, terminal organ

, segmental nerve

, ectoderm

, aCC neuron

, neuron &&of central nervous system | restricted

, embryonic/larval spiracle

, fascicle &&of anterior commissure

, commissure

, ventral neurogenic region | segmentally repeated

, posterior midgut proper primordium

, salivary gland body primordium

, fascicle &&ofposterior commissure

, gonad

, intersegmental nerve

, neuroblast

segmentally repeated , inclusive hindgut primordium

, embryonic peripheral nervous system

, epidermis | dorsal

, VUM neuron

" FBgn0004394 pdm2 POU domain protein 2 http://flybase.net/reports/FBgn0004394.html "FBgn0032441, FBgn0032443" protein_coding_gene "0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003677=DNA binding, 0043565=sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007398=ectoderm development, 0006355=regulation of transcription, DNA-templated, 0048699=generation of neurons, 0007399=nervous system development, 0007417=central nervous system development, 0014019=neuroblast development" 0005634=nucleus "Pdm-2, pdm-2, miti, POU domain protein 2, CG12287, CG15487, pdm, dOct2, POU domain prot 2, dPOU28/pdm-2, Pdm, CG15486, dim, Oct2, Pdm2, Oct-2, dPOU28, dPOU-28, dpou28, didymous, miti-mere, Miti-mere" "IPR001356=Homeobox domain, IPR010982=Lambda repressor-like, DNA-binding domain, IPR000327=POU-specific domain, IPR013847=POU domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG12287 16-Dec-15 2015_12 "ENSDARG00000011570(pou6f1),ENSDARG00000071722" WBGene00000431(ceh-6) ENSXETG00000006231(pou2f1) "ENSMUSG00000008496(Pou2f2),ENSMUSG00000026565(Pou2f1),ENSMUSG00000032015(Pou2f3)" " embryonic stage | late , embryonic stage , embryonic stage | gastrula , embryonic stage | mid , embryonic stage | mid-late , embryonic stage | cellular blastoderm , embryonic stage | stage 10 , embryonic stage | stage 6 , embryonic stage | early , embryonic stage | stage 9 , embryonic stage | stage 5 " " abdominal segment 8--9 &&of peripheral nervous system

, central nervous system | restricted

, abdominal dorsal multidendritic neuron

, neurogenic region

, larval labral segment sense organ

, scolopidial ligament cell &&of dorsal thoracic cluster &&of thoracic segment 2--3

, embryonic peripheral nervous system | restricted

, ectoderm | stripes

, embryonic/larval hindgut

, embryonic brain | restricted

, optic lobe

, embryonic central nervous system | restricted

, labral segment

, tracheal primordium

, scolopidial ligament cell &&of lateral abdominal cluster &&of abdominal segment 1--7

,

20-40% egg length ,

30-50% egg length , abdominal 1--7 dorsal bipolar neuron dbp

, neuroblast | restricted

, parasegment 7

, sensory neuron &&of embryonic/larval foregut

, embryonic neuron

,organism | segment polarity , larval labral segment sense organ | precursor

, dorsal thoracic bd1

, chordotonal organ &&of lateral thoracic cluster &&of prothoracic segment

, organism | odd pair rule

, larval brain

, organism | 20-50% egg length

,

segment polarity , hypophysis

, embryonic central nervous system | presumptive

, organism | 90-100% egg length

" embryonic stage | stage 11 ganglion mother cell GMC4-2a

"viable,fertile,lethal,heat sensitive,neuroanatomy defective" "RP2 motor neuron,ectopic,embryonic ganglion mother cell,neuroblast NB4-2,embryonic abdominal segment 2,ganglion mother cell,RP2sib neuron,heat sensitive,embryonic abdominal segment 6,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval head,ganglion mother cell GMC4-2a,U5 neuron,supernumerary,U3 neuron,U4 neuron,neuroblast NB3-3" DRSC02496 EK -0.767183749 -0.260164455 -1.701163938 1.467915636 2.168064741 1.363649743 FBgn0003887 ë_Tub56D ë_-Tubulin at 56D http://flybase.net/reports/FBgn0003887.html protein_coding_gene "0003924=GTPase activity, 0005200=structural constituent of cytoskeleton, 0005525=GTP binding" "0016203=muscle attachment, 0051298=centrosome duplication, 0051258=protein polymerization" "0005874=microtubule, 0005737=cytoplasm" "beta-tubulin 56D, beta1 tubulin, beta-Tub, beta, betatubulin, BETA 56D, Dmbeta1, b-tubulin56D, beta-Tubulin, beta[[1]] tubulin, beta-1-tubulin, DTB2, beta-Tub56D, 1t, beta56D, CG9277, T, beta-Tubulin 56D, beta-tub, beta1, A1ZBL0_DROME, beta[[1]]-tubulin, beta1-tubulin, Tubulin beta-1 chain, beta1t, Tub, beta-tubulin-56D, betaTub, TBB1_DROME, beta-Tubulin at 56 D, beta1-Tubulin, betatub56D, beta-Tubulin at 56D, tubulin, Tubulin, beta-tubulin, beta-tubulin56D, beta-1 tubulin, B1t, beta1tub, beta tubulin, betatub(56D), beta1Tub, Beta tubulin, betaTub1, Tubulin beta1-chain, betaTub56D, beta1-tub" "IPR003008=Tubulin/FtsZ, GTPase domain, IPR023123=Tubulin, C-terminal, IPR013838=Beta tubulin, autoregulation binding site, IPR017975=Tubulin, conserved site, IPR008280=Tubulin/FtsZ, C-terminal, IPR018316=Tubulin/FtsZ, 2-layer sandwich domain, IPR002453=Beta tubulin, IPR000217=Tubulin" CG9277 16-Dec-15 2015_12 YFL037W(TUB2) " embryonic stage | stage 17 , embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 11 , prepupal stage , embryonic stage | 0-21 hr , larval stage | first instar , larval stage | second instar , embryonic stage | stage 8 , embryonic stage -- adult stage , pupal stage , embryonic stage | early " " apodeme

, supraesophageal ganglion

, embryonic central nervous system | primordium

, dorsal mesothoracic disc

, ventral nerve cord

, central nervous system

" " adult stage | male , larval stage |first instar , oogenesis stage && adult stage | female , adult stage | female , P | stage P1-15 , embryonic stage | 0-19 hr " " ovary

, organism

, testis

" "lethal,recessive,fertile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,midline primordium" DRSC07583 IE 2.236022942 -0.952692625 2.266093914 -1.65373703 -0.510108366 -1.24453863 FBgn0000529 bsh brain-specific homeobox http://flybase.net/reports/FBgn0000529.html FBgn0010392 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0007420=brain development, 0048663=neuron fate commitment" 0005634=nucleus "lambdaE86, brain specific homeobox, Bsh, Hox11-310, BSH, E86, CG10604, Brain-specific homeobox" "IPR001356=Homeobox domain, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR020479=Homeodomain, metazoa, IPR000047=Helix-turn-helix motif" CG10604 16-Dec-15 2015_12 " embryonic stage | >6hr , adult stage , larval stage | third instar , larval stage--adult stage " " lamina

, optic lobe

" embryonic stage | stage 11-16 supraesophageal ganglion | restricted

"viable,neuroanatomy defective,somatic clone" "medullary intrinsic neuron Mi1,somatic clone,transmedullary neuron,ectopic,lamina monopolar neuron L3,lamina monopolar neuron L4,supernumerary" FBgn0000808 gd gastrulation-defective http://flybase.net/reports/FBgn0000808.html protein_coding_gene "0008233=peptidase activity, 0008236=serine-type peptidase activity, 0004252=serine-type endopeptidase activity" "0016485=protein processing, 0007311=maternal specification of dorsal/ventral axis, oocyte, germ-line encoded, 0009950=dorsal/ventral axis specification, 0008063=Toll signaling pathway, 0006508=proteolysis" 0005576=extracellular region "CG1505, fs(1)573, fs(1)18, SP186, Gastrulation Defective, GD, fs(1)190-5, fs(1)gd, gastrulation defective, Gd, gas, fs(1)A573, fs(1)M18" "IPR009003=Peptidase S1, PA clan, IPR001254=Serine proteases, trypsin domain" CG1505 16-Dec-15 2015_12 " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >S10 , embryonic stage | early " " nurse cell

, follicle cell

, oocyte

, ovary

" " adult stage && oogenesis stage , embryonic stage | early " ovary

"lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal,maternal effect,female sterile,recessive,hyperplasia,heat sensitive,germline clone,non-rescuable maternal effect,partially,dorsal/ventral axis specification defective,viable" "embryonic/first instar larval cuticle,filzkorper,denticle belt,embryo,dorsal,gastrula embryo,maternal effect,amnioserosa,mesoderm,germline clone,neurogenic region,egg,ventral" FBgn0000715 FMRFa FMRFamide http://flybase.net/reports/FBgn0000715.html protein_coding_gene "0005179=hormone activity, 0005184=neuropeptide hormone activity, 0071855=neuropeptide receptor binding" "0008345=larval locomotory behavior, 0007218=neuropeptide signaling pathway, 0002209=behavioral defense response, 1900075=positive regulation of neuromuscular synaptic transmission, 0006942=regulation of striated muscle contraction, 0010459=negative regulation of heart rate, 0045822=negative regulation of heart contraction, 0008344=adult locomotory behavior" 0005615=extracellular space "Drm-FMRFamide-4, DPKQDFMRF-amide, Drm-FMRFamide-1, dFMRFa-8, Drm-FMRFa2, FMRFa-3, Drm-FMRF-5, FMRFa-2, FMRFa-6, dFMRFa-2, SDNFMRFamide, Drm-FMRFa3, dFmrf, FMRFamide, fmrf, FMRFa-like, Drm-FMRF-4, FRMFamide, Drm-FMRF-3, Drm-FMRFamide-3, FMRFa-7, Drm-FMRFamide-5, Drm-FMRFa1, dFMRFa-4, FMRF amide homologue precursor, amino acid amidated neuropeptide, dFMRFa-5, Drm-FMRFamide-2, Drm-FMRF-1, FMRFa-4, FMRF-amide, Drm-FMRFa4, dFMRF, dFMRFa, FMRFa-1, Fmrf, dFmrfa, dFMRFa-1, FMRFa-5, dFMRFa-6, dFMRFa-7, CG2346, FMRFamide prohormone, FMRFamide-related, DPKQDFMRFamide, dFMRFamide, FMRFa-8, TPAEDFMRFamide, Drm-FMRF-2, dFMRFa-3, FMRFa, FMRF" IPR002544=FMRFamide-related peptide-like CG2346 16-Dec-15 2015_12 " embryonic stage | stage >=16 , larval stage , prepupal stage--adult stage , larval stage--adult stage , adult stage , embryonic stage | late " " neuron | subset

, central nervous system | restricted

" " prepupal stage--adult stage , embryonic stage | stage >=15 , larval stage " " central nervous system | restricted

, neuron | subset

" "lethal,viable" FBgn0004364 18w 18 wheeler http://flybase.net/reports/FBgn0004364.html protein_coding_gene 0004888=transmembrane signaling receptor activity "0019730=antimicrobial humoral response, 0007165=signal transduction, 0007275=multicellular organismal development, 0007155=cell adhesion, 0030703=eggshell formation, 0006955=immune response, 0019731=antibacterial humoral response, 0007297=ovarian follicle cell migration, 0009653=anatomical structure morphogenesis, 0003401=axis elongation, 0006952=defense response, 0048598=embryonic morphogenesis, 0060026=convergent extension" "0005886=plasma membrane, 0016021=integral component of membrane, 0005737=cytoplasm" "wheeler, Toll-2, tlr, toll, 18 Wheeler, CG8896, 18W, Toll like receptor, 18Wheeler, 18-w, l(2)00053, 18-wheeler, CT25100, 18wheeler, toll receptor, 18-Wheeler" "IPR000483=Cysteine-rich flanking region, C-terminal, IPR003591=Leucine-rich repeat, typical subtype, IPR000157=Toll/interleukin-1 receptor homology (TIR) domain, IPR000372=Leucine-rich repeat N-terminal domain, IPR001611=Leucine-rich repeat" CG8896 16-Dec-15 2015_12 WBGene00006593(tol-1) "ENSXETG00000004577(),ENSXETG00000018306()" ENSMUSG00000033777(Tlr13) "ENSG00000165300(SLITRK5),ENSG00000185985(SLITRK2),ENSG00000121871(SLITRK3),ENSG00000179542(SLITRK4),ENSG00000184564(SLITRK6),ENSG00000178235(SLITRK1)" " embryonic stage | stage 11 , embryonic stage | stage >=12 , embryonic stage | stage >=14 , embryonic stage | stage 8 , embryonic stage | stage 15-16 , embryonic stage | stage 7-11 , embryonic stage | stage 5 , embryonic stage | stage 6-10 , embryonic stage | stage 12 , embryonic stage | stage 15,16 , embryonic stage -- adult stage , embryonic stage | stage 16 , embryonic stage | stage 15 " " embryonic central nervous system | primordium

, embryonic/larval dorsal vessel

, salivary gland body primordium

, dorsal mesothoracic disc | presumptive

, amnioproctodeal invagination

, ventral midline

, adult midgut

,

segment polarity , embryonic/larval pharynx | dorsal

, tracheal system

, embryonic/larval salivary gland

, tracheal pit

, organism | even pair rule

, cephalic furrow

, dorsal metathoracic disc | presumptive

, anal plate

, labral segment

, anal pad

, antennal sense organ

, embryonic/larval posterior spiracle

, embryonic/larval hindgut

, maxillary palp sense organ

, embryonic/larval anterior spiracle

" "lethal,recessive,partially lethal - majority die,wild-type,viable,some die during larval stage,lethal - all die before end of larval stage,immune response defective,visible,body color defective,some die during pupal stage" "eye,adult abdomen,macrochaeta,ectopic,wing,leg,ventral thoracic disc,wing disc,antenna,haltere,mesothoracic tergum" FBgn0003042 Pc Polycomb http://flybase.net/reports/FBgn0003042.html "FBgn0015223, FBgn0052443" protein_coding_gene "0001047=core promoter binding, 0003682=chromatin binding, 0035064=methylated histone binding" "0035186=syncytial blastoderm mitotic cell cycle, 2001229=negative regulation of response to gamma radiation, 0016322=neuron remodeling, 0007385=specification of segmental identity, abdomen, 0045892=negative regulation of transcription, DNA-templated, 0042060=wound healing, 0016458=gene silencing, 0006342=chromatin silencing, 0022008=neurogenesis, 0006355=regulation of transcription, DNA-templated" "0005725=intercalary heterochromatin, 0005730=nucleolus, 0000785=chromatin, 0035102=PRC1 complex, 0005634=nucleus" "CG32443, PC, Pc-G, polycomb, PcG, CG7618, DmPc, dPC" "IPR000953=Chromo/chromo shadow domain, IPR023780=Chromo domain, IPR023779=Chromo domain, conserved site, IPR017984=Chromo domain subgroup, IPR016197=Chromo domain-like" CG32443 16-Dec-15 2015_12 "ENSDARG00000070329(cbx8b),ENSDARG00000026781,ENSDARG00000070804(cbx8a),ENSDARG00000004144,ENSDARG00000071051(zgc:101049)" "ENSXETG00000006910(cbx6),ENSXETG00000012826(CBX8),ENSXETG00000006911(cbx7),ENSXETG00000003005(CBX2)" "ENSMUSG00000025578(Cbx8),ENSMUSG00000022421(Cbx6-Nptxr),ENSMUSG00000053411(Cbx7),ENSMUSG00000039989(Cbx4)" "ENSG00000141570(CBX8),ENSG00000183741(CBX6),ENSG00000173894(CBX2)" " egg stage | unfertilized egg , larval stage , embryonic stage | early , embryonic stage | late , embryonic stage | 0-8 hr , embryonic stage " " unfertilized egg

, embryonic/larval salivary gland

, embryonic central nervous system

,

ubiquitous " " embryonic stage , adult stage && oogenesis stage | stage S1-2 , adult stage && oogenesis stage | stage S10-14 , embryonic stage | early , adult stage && oogenesis stage | stage S9-14 , larval stage , adult stage && oogenesis stage " " thoracico-abdominal ganglion

, embryonic central nervous system

, egg chamber

, embryonic/larval pharynx

, embryonic/larval salivary gland

, subesophageal ganglion

, follicle cell

,

ubiquitous , nurse cell

, larval fat body | anterior

, germarium

, supraesophageal ganglion

" "visible,dominant,homeotic,mitotic cell cycle defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,heat sensitive,male,suppressor of variegation,non-suppressor of variegation,non-enhancer of variegation,neuroanatomy defective,somatic clone,decreased cell number,tumorigenic,wild-type" "mesothoracic leg,mesothoracic segment,sex comb,ectopic,metathoracic leg,abdominal segment,wing,mesothoracic leg & sex comb | ectopic,metathoracic leg & sex comb | ectopic,anaphase | embryonic stage,telophase | embryonic stage,leg,supernumerary,genital disc primordium,ventral mesothoracic disc primordium,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,antenna,presumptive embryonic/larval central nervous system,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,midgut constriction,embryonic/larval brain,metathoracic segment,adult abdominal segment 1,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,male,prothoracic leg,abdominal segment 4,abdominal segment 5,female,haltere,embryonic thoracic segment,embryonic abdominal segment,abdominal tergite 4,sternopleural bristle,adult external mesothorax,adult external prothorax,gonadal sheath proper primordium,heat sensitive,larval segment,larval head,photoreceptor cell,somatic clone,eye,eye disc,morphogenetic furrow,embryonic head,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,larval abdominal segment 4,larval abdominal segment 5,dendrite | somatic clone,neuroblast,dendrite & dorsal multidendritic neuron ddaC | somatic clone,sex comb tooth" FBgn0001077 ftz fushi tarazu http://flybase.net/reports/FBgn0001077.html FBgn0014176 protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003700=sequence-specific DNA binding transcription factor activity, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding" "0007506=gonadal mesoderm development, 0007417=central nervous system development, 0007350=blastoderm segmentation, 0006355=regulation of transcription, DNA-templated, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0001708=cell fate specification, 0008354=germ cell migration, 0035282=segmentation, 0035290=trunk segmentation, 0007366=periodic partitioning by pair rule gene, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0006357=regulation of transcription from RNA polymerase II promoter, 0035289=posterior head segmentation" 0005634=nucleus "Ftz, fushitarazu, Fushi tarazu, FTZ, DmFtz, Dmftz, CG2047, Dm-ftz, Fushi-Tarazu, Fushi-tarazu, BG:DS07876.1, fushi-tarazu, Dm-Ftz, FUSHI-TARAZU, Fushi Tarazu, l(3)84Ag, Ultra-abdominal-like, Ual" "IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR005567=Fushi tarazu, N-terminal" CG2047 16-Dec-15 2015_12 "ENSXETG00000001799(HOXD4),ENSXETG00000023484(HOXC4),ENSXETG00000021973(hoxb4)" " embryonic stage , embryonic stage | stage 4-12 , embryonic stage | 0-12hr , embryonic stage | stage 10 , embryonic stage | 2-4hr , embryonic stage | stage 3 , embryonic stage | early , embryonic stage | cellular blastoderm , embryonic stage | stage 4-14 " " parasegment 12 | pair rule

, ventral nerve cord | pair rule

,

odd pair rule ,

20-70% egg length , parasegment 14 | pair rule

, parasegment 2 | pair rule

, parasegment 8 | pair rule

, parasegment 4 | pair rule

, parasegment 2,4,6,8,10,12,14 , parasegment 10 | pair rule

, parasegment 6 | pair rule

" " embryonic stage | cellular blastoderm , embryonic stage | stage 10-12 , embryonic stage | stage 4-12 , embryonic stage | stage 4 , embryonic stage | 12-15hr , embryonic stage | 3-5hr , embryonic stage | stage 11,12 , embryonic stage | 5-6hr , embryonic stage | stage 10 , embryonic stage | stage >9 , embryonic stage | blastoderm , embryonic stage , embryonic stage | 3-14hr , embryonic stage | stage 5 , embryonic stage | stage 4-8 " "

pair rule , MP1b neuron

, parasegment 4 | pair rule

, parasegment 12 | pair rule

, parasegment 4

, embryonic/larval hindgut

, RP2 neuron

, parasegment 2

,

odd pair rule , dMP2 neuron

, embryonic central nervous system | restricted

, neuroblast MP2

, parasegment 14

, pole cell | anterior to

, parasegment 6

, embryonic/larval proventriculus

, parasegment 8

, MP1 neuron

, parasegment 6 | pair rule

, aCC neuron

, parasegment 10

, embryonic central nervous system | segmentally repeated

, RP1 neuron

, pCC neuron

, parasegment 10 | pair rule

, parasegment 2 | pair rule

, glioblast

, ganglion mother cell GMC1-1a

, organism | 70-90% egg length

, parasegment 14 | pair rule

, parasegment 8 | pair rule

, organism | pair rule

, vMP2 neuron

, MP1a neuron

, parasegment 12

" "lethal,recessive,pair rule phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,heat sensitive,viable,female,visible,dominant,partially,homeotic,increased cell death" "dorsal closure embryo,presumptive embryonic/larval central nervous system,hypostomal sclerite,parasegment 1,parasegment 2,embryonic labial segment,embryonic maxillary segment,embryonic epidermis,presumptive embryonic/larval nervous system,denticle belt,parasegment 10,parasegment 12,parasegment 14,parasegment 4,parasegment 6,parasegment 8,embryonic abdomen,embryonic thorax,prothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic segment,heat sensitive,embryonic/first instar larval cuticle,parasegment 3,parasegment 5,parasegment,embryo,segment,parasegment 7,parasegment 9,parasegment 11,parasegment 13,parasegment 15,adult abdominal segment 2,adult abdominal segment 4,larval segment,haltere,wing,ectopic,Keilin's organ,metathoracic Keilin's organ,adult abdominal segment 1,adult abdominal segment 3,posterior,adult abdomen,adult mesothoracic segment,adult metathoracic segment,anterior,abdominal segment 1,abdominal segment 3,abdominal segment 5,abdominal segment 7,gonadal sheath proper primordium,fat body/gonad primordium,extended germ band embryo,embryonic abdominal segment 2,embryonic abdominal segment 4,embryonic abdominal segment 6,embryonic abdominal segment 8,abdominal segment 4,tergite,mesothoracic ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal tergite 1,arista,third segment of antenna,antennal segment 3 & bract | ectopicDll-md23,antenna,T1 beard,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic head,leg,tarsal segment 3,tarsal segment 4,mesothoracic tibia,mesothoracic tibial apical bristle,pretarsus,antennal disc,distal,prothoracic segment,embryonic abdominal segment 1" FBgn0000075 amd ë± methyl dopa-resistant http://flybase.net/reports/FBgn0000075.html FBgn0032757 protein_coding_gene "0030170=pyridoxal phosphate binding, 0004058=aromatic-L-amino-acid decarboxylase activity, 0019239=deaminase activity, 0016831=carboxy-lyase activity" "0006520=cellular amino acid metabolic process, 0042417=dopamine metabolic process, 0006584=catecholamine metabolic process, 0040003=chitin-based cuticle development" "alpha methyl dopa, l(2)amd, l(2)amd[H], l(2)37Bk, CG10501, alpha-methyl dopa resistant, CG17345, DHPAA synthase, alpha-methotrexate deficient, transcription unit No. 1, X04695, fAMD, dopa decarboxylase, alpha methyl dopa-resistant, l(2)amd alpha-methyldopa hypersensitive, AMD-r" "IPR015424=Pyridoxal phosphate-dependent transferase, IPR021115=Pyridoxal-phosphate binding site, IPR015422=Pyridoxal phosphate-dependent transferase, major region, subdomain 2, IPR010977=Aromatic-L-amino-acid decarboxylase, IPR015421=Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR002129=Pyridoxal phosphate-dependent decarboxylase" CG10501 16-Dec-15 2015_12 " embryonic stage | stage >12 , larval stage , embryonic stage | stage >11 , embryonic stage | stage 8 , larval stage | third instar , embryonic stage | stage >=16 , embryonic stage | stage 5 , embryonic stage | stage >=15 , embryonic stage | stage 4 " " embryonic/larval proventriculus

, imaginal disc

, anal pad

, embryonic/larval esophagus

, ventral nerve cord

, stomodeum | primordium

, eye-antennal disc

, ventral thoracic disc

, proctodeum

, embryonic/larval tracheal system

, ring gland

, lymph gland

, embryonic/larval hindgut

, larval brain

, embryonic/larval pharynx | anlagen

, dorsal mesothoracic disc

, epidermis

, embryonic/larval pharynx | dorsal

, embryonic/larval foregut

, Malpighian tubule primordium

, embryo | dorsal

" "lethal,recessive,wild-type,partially,chemical sensitive,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,viable" "cuticle,anal pad,anal slit" FBgn0039286 dan distal antenna http://flybase.net/reports/FBgn0039286.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005515=protein binding" "0048749=compound eye development, 0006355=regulation of transcription, DNA-templated, 0021556=central nervous system formation, 0007379=segment specification" 0005634=nucleus "fernandez, Dan, Tintin, CG11849, fer" "IPR007889=DNA binding HTH domain, Psq-type, IPR009057=Homeodomain-like" CG11849 16-Dec-15 2015_12 " pupal stage | early , larval stage | third instar " " eye-antennal disc | restricted

, antennal disc | restricted & central

, eye disc | restricted

" "viable,visible,neuroanatomy defective,lethal" "embryonic/larval hemocyte | third instar larval stage,antennal segment 3 & macrochaeta | ectopic,unguis,antenna,third segment of antenna,leg,distal,arista,ectopic,antennal segment 3 & macrochaeta | ectopicDll-md23,eye,ommatidium,interommatidial bristle,ventral nerve cord,presumptive embryonic/larval nervous system,germ band,rostral membrane,wing,wing margin bristle,wing hinge" FBgn0013973 Gycë_100B Guanylyl cyclase ë_-subunit at 100B http://flybase.net/reports/FBgn0013973.html protein_coding_gene "0004383=guanylate cyclase activity, 0020037=heme binding" "0006182=cGMP biosynthetic process, 0035556=intracellular signal transduction" "0008074=guanylate cyclase complex, soluble" "dgcbeta1, Gycbeta100B, gycbeta100B, Gycbeta-100B, dgcb1, sGCbeta1, sGCbeta100B, CG1470, Dgcbeta1, Dgc beta 1" "IPR001054=Adenylyl cyclase class-3/4/guanylyl cyclase, IPR029787=Nucleotide cyclase, IPR018297=Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR011645=Haem NO binding associated, IPR011644=Heme-NO binding, IPR024096=NO signalling/Golgi transport ligand-binding domain" CG1470 16-Dec-15 2015_12 ENSDARG00000070034 "WBGene00001552(gcy-32),WBGene00001554(gcy-34),WBGene00001556(gcy-36),WBGene00001555(gcy-35)" ENSXETG00000022399(GUCY1B3) ENSMUSG00000028005(Gucy1b3) ENSG00000061918(GUCY1B3) adult stage adult head

adult stage " optic lobe

, neuropil

" "viable,fertile" FBgn0022984 qkr58E-3 quaking related 58E-3 http://flybase.net/reports/FBgn0022984.html FBgn0025581 protein_coding_gene "0003723=RNA binding, 0003729=mRNA binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0006915=apoptotic process" "0005634=nucleus, 0016607=nuclear speck" "KH domain encompassing protein 1, KEP1, QKR58E-3, qkr58e-3, CG3584, qrk58E-3, kep1" "IPR004088=K Homology domain, type 1, IPR004087=K Homology domain" CG3584 16-Dec-15 2015_12 WBGene00022101(Y69A2AR.32) " adult stage | male , embryonic stage -- adult stage " "male fertile,viable,female fertile,partially,immune response defective" "egg,dorsal appendage,eye,ectopic" FBgn0002629 E(spl)m4-BFM "Enhancer of split m4, Bearded family member" http://flybase.net/reports/FBgn0002629.html protein_coding_gene "0005515=protein binding, 0031625=ubiquitin protein ligase binding" "0001708=cell fate specification, 0007219=Notch signaling pathway, 0007423=sensory organ development" 0005634=nucleus "E(spl) region transcript 4, E(spl) region transcript m4, E(spl)m4, enhancer of split m4, HLHm4, m4, DmelCG6099, CG6099, E(spl) m4" IPR029686=Enhancer of split malpha/m4 CG6099 16-Dec-15 2015_12 " larval stage | third instar , embryonic stage | stage 11-12 , embryonic stage | stage 5 , embryonic stage | stage 11 , P | stage P4 , embryonic stage | 2-10 hr , embryonic stage | stage 8-17 , embryonic stage | stage 10 , embryonic stage | stage 7-11 , embryonic stage | stage 6,7 , embryonic stage | stage >7 , embryonic stage | stage 11-14 " " proneural cluster &&of ventral thoracic disc

, mesoderm

, proneural cluster | presumptive

, dorsal mesothoracic disc

, vitellophage

, epidermis | restricted

, ventral thoracic disc

, sensillum campaniformium &&of wing

, proneural cluster &&of eye disc

, ventral neurogenic region

, morphogenetic furrow | anterior to

, posterior midgut proper primordium

, ectoderm

, mesectoderm

, supraesophageal ganglion

, proneural cluster &&of dorsal mesothoracic disc

, eye disc

, organism | striped

, stomatogastric nervous system | primordium

, optic lobe | primordium

" "visible,somatic clone" "macrochaeta,ectopic,sensory mother cell,scutellar bristle,campaniform sensillum of anterior crossvein,sensillum campaniformium,microchaeta,dorsal row & sensory mother cellap-md544,precursor,sensillum campaniformium of dorsal radius,somatic clone,central nervous system,peripheral nervous system,eye,ommatidium,lens,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,head bristle" FBgn0004108 Nrt Neurotactin http://flybase.net/reports/FBgn0004108.html protein_coding_gene 0052689=carboxylic ester hydrolase activity "0007417=central nervous system development, 0007411=axon guidance, 0007413=axonal fasciculation, 0007409=axonogenesis" "0016323=basolateral plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane, 0005737=cytoplasm" "BP106, Nrt BP106, NEUROTACTIN, NRT BP106, Dab, l(3)73Be, CG9704, BcDNA:LD22004, DAB, dab, Neurotactin, disabled, neu, NRT, MabBP106, nrt, Neur, NT, neurotactin" "IPR029058=Alpha/Beta hydrolase fold, IPR019819=Carboxylesterase type B, conserved site, IPR002018=Carboxylesterase, type B" CG9704 16-Dec-15 2015_12 " embryonic stage | early , embryonic stage , embryonic stage | stage >=9 , embryonic stage | stage 5 , embryonic stage && pupal stage && adult stage , embryonic stage && pupal stage , embryonic stage && adult stage , larval stage | third instar , embryonic stage | cellular blastoderm " " fat body primordium

, embryonic central nervous system | presumptive

, embryonic nervous system

, organism | 40-90% egg length dorsal

, embryonic peripheral nervous system | restricted

,

10-90% egg length ventral " " embryonic stage , embryonic stage | stage 5-7 , larval stage | third instar , embryonic stage | stage 12-16 , embryonic stage | stage 13-16 , embryonic stage | embryonic cycle 14 , embryonic stage | cellular blastoderm , embryonic stage -- adult stage , pupal stage , embryonic stage | embryonic cycle 13 , embryonic stage | stage 7 , embryonic stage | stage 10-17 , embryonic stage | stage 5 , embryonic stage | stage 5-10 , larval stage , embryonic stage | stage 16 , embryonic stage | stage 13-17 , embryonic stage | stage >=9 " " multidendritic neuron

, anterior transverse furrow

, photoreceptor cell

, embryonic central nervous system

, visceral mesoderm

, cell body

, neuroblast

,

10-90% egg length ventral , photoreceptor cell

, larval central nervous system

, cephalic furrow

, sensory neuron &&of wing

, fat body primordium

, embryonic peripheral nervous system | restricted

, ventral furrow

, anterior midgut proper primordium

, embryonic nervous system

, dorsal vessel primordium

, organism | 40-90% egg length & dorsal

, mesoderm

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

, dorsal fold

, posterior transverse furrow

, larval optic lobe

, neuron &&of ocellus

, ventral thoracic disc

, ventral nerve cord commissure

, ventral nerve cord

, eye-antennal disc

, supraesophageal ganglion

, embryonic central nervous system | presumptive

, amnioserosa

, neuron

" "viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective" "ocellar nerve,ventral nerve cord,axon | embryonic stage,presumptive embryonic/larval central nervous system,eye photoreceptor cell,somatic clone,ommatidium,photoreceptor cell R7,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,commissure" FBgn0039581 Moca-cyp Moca-cyp http://flybase.net/reports/FBgn0039581.html "FBgn0045066, FBgn0045067, FBgn0045068, FBgn0046249" protein_coding_gene 0003755=peptidyl-prolyl cis-trans isomerase activity "0006457=protein folding, 0000413=protein peptidyl-prolyl isomerization, 0000398=mRNA splicing, via spliceosome" "0071011=precatalytic spliceosome, 0005654=nucleoplasm, 0071013=catalytic step 2 spliceosome, 0005634=nucleus" "moca, CG1866, anon-WO0147981.13, BEST:LD38313, anon-WO0147981.4, anon-WO0147981.5" "IPR024936=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000=Cyclophilin-like domain, IPR002130=Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR020892=Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG1866 16-Dec-15 2015_12 ENSDARG00000044431(ppig) YJR032W(CPR7) ENSMUSG00000042133(Ppig) ENSG00000138398(PPIG) " embryonic stage | stage 6-10 , embryonic stage | stage 8-13 , embryonic stage | stage 5 , embryonic stage | stage 1-4 , embryonic stage | stage 15 " " mesoderm

, embryonic central nervous system

, organism

,

, anterior embryonic/larval midgut && posterior embryonic/larval midgut

, ventral nerve cord && hindgut

" " embryonic stage | 2-21 hr , embryonic stage | stage 9-11 , embryonic stage | stage >5 , embryonic stage | 9-24 hr , embryonic stage | stage 1-7 , embryonic stage | stage >13 " " mesoderm

, organism

, anterior embryonic/larval midgut && posterior embryonic/larval midgut

,

, ventral nerve cord && hindgut && pharynx && proventriculus

, embryonic central nervous system

" "viable,fertile" FBgn0265998 Doa Darkener of apricot http://flybase.net/reports/FBgn0265998.html "FBgn0024584, FBgn0028087, FBtr0085332, FBtr0085333, FBtr0085334, FBtr0085335, FBan0001658, FBgn0053553, FBgn0000480, FBgn0010760, FBgn0014864, FBgn0051049, FBgn0053204, FBgn0259220" protein_coding_gene "0005524=ATP binding, 0004712=protein serine/threonine/tyrosine kinase activity, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity" "0030717=karyosome formation, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 0007417=central nervous system development, 0042051=compound eye photoreceptor development, 0007548=sex differentiation, 0048749=compound eye development, 0007399=nervous system development, 0008362=chitin-based embryonic cuticle biosynthetic process, 0007350=blastoderm segmentation, 0009306=protein secretion, 0046777=protein autophosphorylation, 0045494=photoreceptor cell maintenance, 2000255=negative regulation of male germ cell proliferation, 0000381=regulation of alternative mRNA splicing, via spliceosome, 0006468=protein phosphorylation, 0048477=oogenesis, 0035071=salivary gland cell autophagic cell death, 0048102=autophagic cell death, 0008407=chaeta morphogenesis, 0000165=MAPK cascade, 0048854=brain morphogenesis" "0005875=microtubule associated complex, 0005783=endoplasmic reticulum, 0005737=cytoplasm, 0005634=nucleus" "CG1658, CG31049, Mosaic suppressor, lethal (3) s2784, darkener of apricot, DOA, CG33553, Msu, l(3)01705, CG42320, l(3)s2784, CG33204, doa, l(3)S084402, lethal (3) S084402, 0844/02, DOA/CLK2" "IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR011009=Protein kinase-like domain, IPR008271=Serine/threonine-protein kinase, active site" CG42320 16-Dec-15 2015_12 WBGene00006517(tag-172) " embryonic stage | stage 13-17 , adult stage , embryonic stage | stage >=1 , embryonic stage | stage 13 , embryonic stage | early , embryonic stage | stage 10-11 , embryonic stage -- adult stage , oogenesis stage && adult stage | female , larval stage | late third instar larval stage , embryonic stage , larval stage | third instar , pupal stage " " ventral nerve cord

, embryonic brain | surrounding

, mesoderm

, adult thorax && adult abdomen

, ovary

, adult head

, eye-antennal disc

, embryonic brain

, labral segment

, procephalic segment

, ectoderm

, visceral mesoderm | surrounding

, embryonic/larval tracheal pit

, dorsal mesothoracic disc

, embryonic optic lobe

" " adult stage , embryonic stage | early , embryonic stage | stage 10-11 , larval stage , larval stage | late third instar larval stage , pupal stage | 0-24 hr , embryonic stage | stage 13-17 , embryonic stage | 0-24 hr , larval stage | third instar , embryonic stage " " ovary

, mesoderm

, larval salivary gland

, adult head

, embryonic/larval fat body

, embryonic central nervous system

, ectoderm

, eye-antennal disc

, Bolwig's nerve

,

ubiquitous , embryonic brain

" FBgn0011286 RyR Ryanodine receptor http://flybase.net/reports/FBgn0011286.html "FBgn0010268, FBgn0022194" protein_coding_gene 0005219=ryanodine-sensitive calcium-release channel activity "0060047=heart contraction, 0072347=response to anesthetic, 0070588=calcium ion transmembrane transport, 0006816=calcium ion transport, 0035206=regulation of hemocyte proliferation, 0006874=cellular calcium ion homeostasis, 0006936=muscle contraction" "0016021=integral component of membrane, 0005789=endoplasmic reticulum membrane, 0005875=microtubule associated complex" "D-RyR, RyR, dRyr, DRR, RyRs, DRY, Rya-44F, l(2)k04913, ryanodine receptor, Rya-r76CD, dry, dya, Ryanodine receptor 44F, Ryr, dRyR, ryr, unnamed, Rya-R44F, l(2)k00424, RYR, Rya-r44F, rya-r44F, Ryanodine receptor, CG10844" "IPR003032=Ryanodine receptor Ryr, IPR015925=Ryanodine receptor-related, IPR003877=SPRY domain, IPR014821=Inositol 1,4,5-trisphosphate/ryanodine receptor, IPR011992=EF-hand domain pair, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR013333=Ryanodine receptor, IPR016093=MIR motif, IPR000699=RIH (RyR and IP3R Homology) domain, IPR001870=B30.2/SPRY domain, IPR009460=Ryanodine Receptor TM 4-6, IPR013662=RyR/IP3R Homology associated domain, IPR005821=Ion transport domain" CG10844 16-Dec-15 2015_12 "ENSDARG00000042531(ryr3),ENSDARG00000023797(ryr1b)" WBGene00006801(unc-68) ENSXETG00000002823(RYR1) "ENSMUSG00000021313(Ryr2),ENSMUSG00000057378(Ryr3),ENSMUSG00000030592(Ryr1)" "ENSG00000198626(RYR2),ENSG00000198838(RYR3),ENSG00000196218(RYR1)" " adult stage , embryonic stage | stage >=10 , embryonic stage | stage >=9 , embryonic stage , embryonic stage | stage 14 , embryonic stage | 6-12 hr , larval stage | second instar , larval stage | third instar " " adult brain

, proboscis muscle

, skeletal muscle of head

, mesoderm

, subesophageal ganglion

, skeletal muscle of leg

, mesothoracic extracoxal depressor muscle 66

, larval muscle system

, embryonic/larval hypodermal muscle

, embryonic/larval visceral muscle

, somatic muscle

, embryonic central nervous system

" "viable,chemical resistant,semidominant,locomotor behavior defective,lethal,chemical sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,recessive,feeding behavior defective" "RP2 motor neuron,embryonic/larval muscle system,larva,larval head,embryonic/larval visceral muscle,embryonic/larval dorsal vessel,adult heart,presumptive embryonic/larval muscle system" FBgn0260642 Antp Antennapedia http://flybase.net/reports/FBgn0260642.html "FBgn0000095, FBgn0000111, FBgn0001236, FBgn0003344, FBgn0026857, FBgn0042093" protein_coding_gene "0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0048542=lymph gland development, 0042694=muscle cell fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0014019=neuroblast development, 0006357=regulation of transcription from RNA polymerase II promoter, 0007383=specification of segmental identity, antennal segment, 0007494=midgut development, 0009948=anterior/posterior axis specification, 0007384=specification of segmental identity, thorax, 0007379=segment specification, 0007507=heart development" "0005634=nucleus, 0005737=cytoplasm" "ANTC, AntP, BG:DS07700.1, Antp P2, Sex combs extra, antp, Humeral, Antenapedia, Aus, AntP1, 3.4, Atennapedia, Antennapedia P1, Nasobemia, ANT-P, Antennapedia P2, Antp P1, l(3)84Ba, ANT-C, Sex comb extra, Antennapaedia, DmAntp, Ns, ANTP, Dm-Antennapedia, Scx, antennapedia, DRO15DC96Z, Antp1, Ant, Hu, CG1028, DMANTPE1" "IPR020479=Homeodomain, metazoa, IPR001356=Homeobox domain, IPR017995=Homeobox protein, antennapedia type, IPR001827=Homeobox protein, antennapedia type, conserved site, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site" CG1028 16-Dec-15 2015_12 ENSDARG00000001784(hoxa5a) ENSXETG00000000720(hoxa5) "ENSMUSG00000001657(Hoxc8),ENSMUSG00000056648(Hoxb8),ENSMUSG00000027102(Hoxd8),ENSMUSG00000038236(Hoxa7),ENSMUSG00000038721(Hoxb7)" " larval stage | third instar , larval stage , embryonic stage , embryonic stage | stage >=11 , embryonic stage | blastoderm , pupal stage , embryonic stage | late , embryonic stage--pupal stage , embryonic stage | mid , embryonic stage | stage 17 , embryonic stage | early , embryonic stage | stage 8 , embryonic stage | stage 11-17 , embryonic stage | stage 13 , embryonic stage | stage 1-11 " " dorsal mesothoracic disc | anterior

, dorsal prothoracic disc

, ectoderm

, embryonic central nervous system

, ventral mesothoracic disc

, dorsal mesothoracic disc | restricted

, ventral nerve cord

, parasegment 14 | primordium

, embryonic/larval midgut

, dorsal metathoracic disc

, dorsal mesothoracic disc

, larval brain

, visceral mesoderm &&of anterior embryonic/larval midgut

, ventral prothoracic disc

, parasegment 4--12

, ventral metathoracic disc

, embryonic/larval aorta | vicinity of

, parasegment 6 | primordium

, embryonic/larval muscle system

, ventral mesothoracic disc | anterior

, organism | 60% egg length

, organism | 40-60% egg length

, embryonic/larval somatic muscle

, embryonic mesothoracic segment

, dorsal metathoracic disc | restricted

, mesoderm &&of parasegment 4--6

, embryonic central nervous system | restricted

, embryonic/larval anterior spiracle | vicinity of

, dorsal prothoracic disc | restricted

, ectoderm &&of parasegment 3--14

" " embryonic stage , larval stage , larval stage | third instar , embryonic stage | late , embryonic stage | stage 13-14 , embryonic stage | stage >12 , embryonic stage | stage 13-17 , embryonic stage | stage 16 , embryonic stage | mid-late , embryonic stage | stage >=12 , embryonic stage | stage 8 , embryonic stage | stage 12-13 " " visceral mesoderm

{ 0 hb* } , ventral thoracic disc

, ectoderm

, visceral mesoderm

{ $ kni* } , imaginal disc

, cardioblast &&of embryonic metathoracic segment

, visceral mesoderm &&of parasegment 5--6 &&of embryonic/larval midgut

, embryonic mesothoracic segment

, visceral mesoderm

{ 0 prd* } , visceral mesoderm

{ 0 wg* } , visceral mesoderm

{ - ftz*/prd* } , embryonic central nervous system

, visceral mesoderm

{ 0 odd*/eve* } , visceral mesoderm

, parasegment 5 | visceral mesoderm

, dorsal mesothoracic disc | restricted

, embryonic prothoracic segment

, midgut constriction 1 | posterior

, ventral prothoracic disc | posterior

, visceral mesoderm

{ - opa*/prd* } , visceral mesoderm

{ 0 opa* } , embryonic abdominal neuromere

, visceral mesoderm

{ 0 h* } , visceral mesoderm

{ - Kr* } , peripodial epithelium

, embryonic prothoracic neuromere

, parasegment 5 &&of visceral mesoderm

, cardioblast &&of embryonic abdominal segment 2

, embryonic metathoracic segment

, ventral nerve cord

, embryonic mesothoracic neuromere

, embryonic metathoracic neuromere

, visceral mesoderm

{ 0 run* } , ventral metathoracic disc | anterior

, visceral mesoderm

{ 0 en* } , cardioblast && embryonic pericardial cell &&of embryonic abdominal segment 1

, embryonic abdominal segment 1--7

, embryonic peripheral nervous system | restricted

, parasegment 4--6

, visceral mesoderm

{ $ eve4 } , visceral mesoderm

{ 0 odd* } , dorsal pouch

, parasegment 6 visceral mesoderm

{ 0 ftz* } , labial segment

, ventral mesothoracic disc | anterior

, epidermis

, embryonic dorsal vessel | anterior

, visceral mesoderm

{ - eve3 } " DRSC26749 K -0.777456338 -1.504383972 FBgn0013437 copia\GIP gag-int-pol http://flybase.net/reports/FBgn0013437.html transposable_element_gene "0008270=zinc ion binding, 0003676=nucleic acid binding, 0004190=aspartic-type endopeptidase activity" "0006508=proteolysis, 0015074=DNA integration" "Copia Gag, copiaGIP, copia" "IPR013103=Reverse transcriptase, RNA-dependent DNA polymerase, IPR001878=Zinc finger, CCHC-type, IPR012337=Ribonuclease H-like domain, IPR025724=GAG-pre-integrase domain, IPR001584=Integrase, catalytic core" 16-Dec-15 2015_12 " adult stage | female , larval stage | second instar , embryonic stage , embryonic stage | stage 13 , embryonic stage | extended germ band , adult stage , larval stage | third instar , embryonic stage | stage >=14 , embryonic stage | stage >=13 " " adult fat body

, ventral neurogenic region

, ventral midline | segmentally repeated

, ventral nerve cord

, embryonic central nervous system

, embryonic brain

" FBgn0005631 robo1 roundabout 1 http://flybase.net/reports/FBgn0005631.html FBgn0045796 protein_coding_gene "0004872=receptor activity, 0005515=protein binding, 0008201=heparin binding" "0048813=dendrite morphogenesis, 0072499=photoreceptor cell axon guidance, 0008038=neuron recognition, 0007432=salivary gland boundary specification, 2000274=regulation of epithelial cell migration, open tracheal system, 0009649=entrainment of circadian clock, 0007427=epithelial cell migration, open tracheal system, 0007411=axon guidance, 0022409=positive regulation of cell-cell adhesion, 0001964=startle response, 0031987=locomotion involved in locomotory behavior, 0046716=muscle cell cellular homeostasis, 0050773=regulation of dendrite development, 0016199=axon midline choice point recognition, 0048854=brain morphogenesis, 0008406=gonad development, 0035050=embryonic heart tube development, 0035385=Roundabout signaling pathway, 0003151=outflow tract morphogenesis, 0070983=dendrite guidance, 0008045=motor neuron axon guidance" "0043234=protein complex, 0031982=vesicle, 0005887=integral component of plasma membrane, 0043025=neuronal cell body, 0030424=axon, 0030425=dendrite, 0005886=plasma membrane, 0044295=axonal growth cone, 0071666=Slit-Robo signaling complex" "robo1S, Robo, Robo1, Robo-1, Roundabout, CT32892, CG13521, BEST:GM07780, ROBO, roundabout, dRobo, dRobo1, Roundabout 1, D-Robo1, robo, robo1" "IPR003961=Fibronectin type III, IPR007110=Immunoglobulin-like domain, IPR013783=Immunoglobulin-like fold, IPR003598=Immunoglobulin subtype 2, IPR003599=Immunoglobulin subtype, IPR013098=Immunoglobulin I-set, IPR013106=Immunoglobulin V-set domain" CG13521 16-Dec-15 2015_12 "ENSDARG00000005645(robo3),ENSDARG00000014891,ENSDARG00000069522,ENSDARG00000026784(robo1)" WBGene00004729(sax-3) "ENSXETG00000003938(ROBO3),ENSXETG00000020978(ROBO2),ENSXETG00000020971(ROBO1)" "ENSMUSG00000052516(Robo2),ENSMUSG00000022883(Robo1),ENSMUSG00000032128(Robo3)" "ENSG00000185008(ROBO2),ENSG00000169855(ROBO1),ENSG00000154134(ROBO3)" " embryonic stage | stage 13-15 , embryonic stage | late , embryonic stage | stage 12 , embryonic stage | stage 12-17 , embryonic stage | stage 14 " " longitudinal muscle && muscle attachment site

, longitudinal connective

, MP1 neuron

, vMP2 neuron

, dMP2 neuron

, ventral neurogenic region

, muscle attachment site

, epidermis

, neuron

, sensory neuron | dorsal & subset

, abdominal lateral pentascolopidial chordotonal organ lch5

, pCC neuron

, aCC neuron

" "neuroanatomy defective,male,viable,fertile,stress response defective,circadian rhythm defective,wild-type,lethal,dominant,recessive,somatic clone,neurophysiology defective,female,visible,body color defective,partially lethal - majority die,some die during pupal stage" "tract,ectopic,gustatory receptor neuron,male,prothoracic leg taste bristle chemosensory neuron,macrochaeta,presumptive embryonic/larval central nervous system,longitudinal connective,midline crossing tract,commissure,ganglionic branch primordium,cardioblast,dendrite,class IV dendritic arborizing neuron,dorsal multidendritic neuron ddaC,ventral nerve cord,embryonic/larval neuron,interface glial cell,ventral nerve cord commissure,medial longitudinal fascicle,pCC neuron,thoracic-abdominal embryonic fiber tract,vMP2 tract,fascicle,MP1 neuron,vMP2 neuron,dMP2 neuron,chordotonal organ & axon | lateral,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,A1-7 lateral oblique muscle 1,lch5 neuron,lesA neuron,lateral multidendritic neuron ldaA,posterior fascicle sensory neuron,presumptive embryonic salivary gland,abdominal basiconical sensillum dbd & embryo & nerve terminal,chordotonal organ & embryo & nerve terminal,axon,dorsal abdominal cluster,somatic clone,motor neuron,neuropil,dendrite | somatic clone,gonad,germline cell,embryonic somatic muscle,ventral,RP2 motor neuron,filopodium | embryonic stage,interneuron,axon & pCC neuron,SP1 neuron,anterior commissure,posterior commissure,central nervous system,aCC neuron,presumptive embryonic/larval muscle system,ganglion mother cell GMC1-1a,RP2sib neuron,giant fiber neuron,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,intersegmental nerve,female,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,antennal lobe glomerulus,antennal glomerulus DM2 & olfactory neuronlz-gal4,antennal glomerulus DM6 & olfactory neuronlz-gal4,antennal commissure,synapse | adult stage,synapse | adult stageshakB.lethal.4.1,synapse | adult stagec17,dendriteeve.CQ2,midline crossing tract | embryonic stage 16,dendrite | somatic cloneVGlut-OK371,abdominal lateral pentascolopidial chordotonal organ lch5,dorsal branch | third instar larval stage,trichogen cell,mesothoracic tergum" FBgn0003975 vg vestigial http://flybase.net/reports/FBgn0003975.html protein_coding_gene "0008022=protein C-terminus binding, 0005515=protein binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0016204=determination of muscle attachment site, 0048190=wing disc dorsal/ventral pattern formation, 0007525=somatic muscle development, 0007476=imaginal disc-derived wing morphogenesis, 0035220=wing disc development, 0007480=imaginal disc-derived leg morphogenesis, 0008587=imaginal disc-derived wing margin morphogenesis, 0007472=wing disc morphogenesis, 0007473=wing disc proximal/distal pattern formation, 0042127=regulation of cell proliferation, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0044719=regulation of imaginal disc-derived wing size, 0007346=regulation of mitotic cell cycle, 0001745=compound eye morphogenesis, 0007482=haltere development" 0005634=nucleus "vg21, CG3830, Vg, Vestgial, vestigal, Vestigial, VG" "IPR006627=TDU repeat, IPR011520=Vestigial/tondu" CG3830 16-Dec-15 2015_12 "ENSDARG00000041706(si:dkeyp-93d12.1),ENSDARG00000053773(vgll2b)" ENSXETG00000014041(Q6P4L0_XENTR) "ENSG00000206538(VGLL3),ENSG00000170162(VGLL2)" " embryonic stage | stage 12-17 , embryonic stage | stage 14-16 , embryonic stage | stage 10-13 , embryonic stage && pupal stage && adult stage , larval stage , embryonic stage , larval stage | third instar , embryonic stage | stage 11-17 , embryonic stage | stage 13-16 " " embryonic central nervous system | presumptive | segmentally repeated pattern

, abdomen | restricted

, embryonic central nervous system | presumptive | restricted

, dorsal prothoracic disc

, dorsal metathoracic disc

, ectoderm | stripes <&> dorsal

,

{ $ vg* } , dorsal mesothoracic disc

{ & vg* } , ectoderm | stripes <&> lateral

, larval brain

, head | restricted

, dorsal metathoracic disc | restricted

, dorsal mesothoracic disc

" " larval stage | second instar , larval stage | third instar , pupal stage | 21 hr , pupal stage , embryonic stage | stage >12 " " dorsal mesothoracic disc

, mesothoracic tergum primordium | distal

, myoblast | subset & vicinity of dorsal medial muscle

, mesothoracic lateral longitudinal muscle

, myoblast | subset

, dorsal medial muscle

, adepithelial cell of dorsal mesothoracic disc

, myoblast &&of mesothoracic tergum primordium | proximal

" "lethal,recessive,female sterile,visible,female fertile,male fertile,viable,dominant,lethal - all die before end of pupal stage,somatic clone,some die during pupal stage,germline clone,chemical resistant,cold sensitive,increased cell death,chemical sensitive,heat sensitive,male sterile,conditional,flightless,partially lethal - majority live,sterile,poor,reduced,homeotic,lethal - all die before end of embryonic stage,some die during embryonic stage,cytokinesis defective,size defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "wing,haltere,postnotum,adult thorax,leg,adult metathoracic segment,axillary cord,wing disc,somatic clone,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,embryonic/larval cardial cell,lateral transverse muscle,muscle attachment site,ectopic,distal,cold sensitive,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,temperature conditional,heat sensitive,eye,coxal tergal remotor muscle,indirect flight muscle,wing blade,A1-7 ventral longitudinal muscle 2,conditional,ventral longitudinal muscle,mesothoracic bristle,scutellum,ovary,scutellar bristle,scutum,sensillum campaniformium of proximal dorsal radius,haltere disc,alula,posterior scutellar bristle,mesothoracic tergum,wing pouch,metathoracic leg,tarsal segment,tergite,wing sensillum,wing vein L2 & wing sensillum,wing vein L3 & wing sensillum,mesothoracic leg,prothoracic leg,proboscis,genitalia,antenna,wing margin bristle,wing vein,wing sensillum & sensillum campaniformium | ectopicDll-md23,wing hair,direct flight muscle,basalar muscle 51,basalar muscle 52,second segment of antenna,third segment of antenna,head,mesothoracic tergum & chaeta | supernumerary-C253,thorax,eye disc,anterior wing margin,posterior wing margin,interommatidial bristle,ommatidium,tibia,femur,metatarsus,unguis,posterior" DRSC07715 I -2.037663603 0.302904998 0.916856653 0.055163459 0.252946681 0.493765859 FBgn0001148 gsb gooseberry http://flybase.net/reports/FBgn0001148.html protein_coding_gene "0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007435=salivary gland morphogenesis, 0007268=synaptic transmission, 0006355=regulation of transcription, DNA-templated, 0060025=regulation of synaptic activity, 0007419=ventral cord development, 0022008=neurogenesis, 0007367=segment polarity determination" "0005667=transcription factor complex, 0005634=nucleus, 0005737=cytoplasm" "l(2)gsb, gsb-2, gooseberry distal, CG3388, Gsb, Gsb-d, Gooseberry distal, BSH9, gsbBSH9, GSB-D, BSH-9, l(2)01155, Gooseberry-distal, Gooseberry, gsb-distal, gsbd, BSH9c2, gsb-d" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR001523=Paired domain, IPR011991=Winged helix-turn-helix DNA-binding domain, IPR000047=Helix-turn-helix motif, IPR001356=Homeobox domain" CG3388 16-Dec-15 2015_12 "ENSDARG00000070818,ENSDARG00000020821" " embryonic stage | stage 10-14 , embryonic stage | stage 13 , embryonic stage | 4-8 hr , embryonic stage | gastrula--embryonic stage | extended germ band , embryonic stage | >=stage 5 , embryonic stage | stage 10-12 , embryonic stage | embryonic cycle 14A , embryonic stage | stage 17 , embryonic stage | stage 5-13 " " ectoderm

, ventral nerve cord | anterior

, organism | striped

, abdominal segment 1--11 , thoracic segment | posterior

segmentally repeated , mesoderm

,

75% egg length , anal pad

, embryonic/larval pharynx | restricted

, organism | anterior

, organism | 70% egg length

, head segment

segmentally repeated " " embryonic stage , embryonic stage | stage 14 , embryonic stage | stage 9-11 , larval stage | third instar , embryonic stage | stage 8-11 , embryonic stage | stage 10 , embryonic stage | stage 9-13 , embryonic stage | stage 4-13 , embryonic stage | stage 10-12 , embryonic stage | stage 8-13 , embryonic stage | stage 10-13 , embryonic stage | stage 11 " " neuroblast | row 5

, embryonic/larval pharynx | restricted

, deuterocerebral neuroblast | subset

, neuroblast | row 6/7

, ectoderm && embryonic labral segment | restricted

, female genital disc | restricted

, ventral neurogenic region && embryonic ocular segment | restricted

, ventral neurogenic region | segmentally repeated

, protocerebral neuroblast | subset

, abdominal segment 9--11

, male genital disc | restricted

, intercalary segment | restricted

,

segmentally repeated , neuroblast

, embryonic intercalary segment

, anal pad | restricted

, labral segment | restricted

, ventral neurogenic region && embryonic antennal segment | restricted & anterior

, tritocerebral neuroblast | subset

, mesoderm

" "lethal - all die before end of embryonic stage,recessive,lethal,some die during embryonic stage,wild-type,pair rule phenotype,heat sensitive,visible,viable" "wing,denticle belt,cuticle,RP2 motor neuron,U neuron,U1 neuron,U2 neuron,U3 neuron,posterior commissure,embryonic segment,posterior compartment,ectopic,epidermis,neuroblast NB4-2,presumptive embryonic salivary gland,abdominal 4 ventral denticle belt,EL neuron,abdominal 1 ventral denticle belt,heat sensitive,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,neuroblast MP2,embryonic epidermis,Keilin's organ,embryonic central nervous system & neuroblast | conditional ts,aCC neuron,pCC neuron,RP2sib neuron,neuroblast NB6-4,neuroblast NB7-3,embryonic head,embryonic dorsal epidermis,embryonic central nervous system & neuroblast,eye,adult head,antenna" FBgn0002569 Mal-A2 Maltase A2 http://flybase.net/reports/FBgn0002569.html protein_coding_gene "0004558=alpha-1,4-glucosidase activity, 0003824=catalytic activity, 0043169=cation binding" "0005975=carbohydrate metabolic process, 0006006=glucose metabolic process" "LvpD, mal_A2, lvpD, CG8694, Larval visceral protein D, D, maltase, Drome_A2, hdl cuticle gene cluster" "IPR015902=Glycoside hydrolase, family 13, IPR017853=Glycoside hydrolase superfamily, IPR006047=Glycosyl hydrolase, family 13, catalytic domain, IPR006589=Glycosyl hydrolase, family 13, subfamily, catalytic domain, IPR013781=Glycoside hydrolase, catalytic domain" CG8694 16-Dec-15 2015_12 ENSDARG00000017165(LOC557757) "YIL172C(IMA3),YJL221C(FSP2),YOL157C(IMA2),YGR287C(IMA1),YBR299W(MAL32),YGR292W(MAL12),YJL216C(IMA5)" "WBGene00000225(atgp-2),WBGene00000224(atgp-1)" ENSXETG00000002750(SLC3A1) ENSMUSG00000024131(Slc3a1) ENSG00000138079(SLC3A1) " larval stage | second instar , adult stage , larval stage | first instar , larval stage | early third instar larval stage " organism

viable FBgn0027950 MBD-like Methyl-CpG binding domain protein-like http://flybase.net/reports/FBgn0027950.html FBgn0029156 protein_coding_gene "0008327=methyl-CpG binding, 0005515=protein binding, 0003714=transcription corepressor activity, 0042803=protein homodimerization activity, 0042826=histone deacetylase binding" "0045892=negative regulation of transcription, DNA-templated, 0007275=multicellular organismal development" "0016581=NuRD complex, 0005700=polytene chromosome, 0005634=nucleus" "MBD2-3, DmMbd2/3, MBD-like, dMBD-like, methyl-CpG-binding-domain-like-protein, MBD2/3, CG8208, dMbD2/3, MBD3, MBD2, dMBD2/3, Dm Mbd2/3" "IPR016177=DNA-binding domain, IPR001739=Methyl-CpG DNA binding, IPR025884=Methyl-CpG binding protein 2/3, C-terminal domain" CG8208 16-Dec-15 2015_12 ENSDARG00000042029(mbd3b) "ENSXETG00000013688(MBD2),ENSXETG00000013593(mbd3)" "ENSMUSG00000024513(Mbd2),ENSMUSG00000035478(Mbd3)" "ENSG00000134046(MBD2),ENSG00000071655(MBD3)" adult stage " testis

, ovary

" " adult stage , embryonic stage | cellular blastoderm , embryonic stage | 6-20 hr , embryonic stage | 0-12 hr , embryonic stage | stage < 4 " " spermatogonium

, primary gonial cell

, spermatocyte

, organism

" "viable,fertile,small body,suppressor of variegation,dominant" "heart primordium,mitotic anaphase & nuclear chromosome" FBgn0026196 nop5 nop5 http://flybase.net/reports/FBgn0026196.html FBgn0022271 protein_coding_gene "0009267=cellular response to starvation, 0006364=rRNA processing" 0005730=nucleolus "2/30, FBgn0026196, DNOP5, CG10206, NOP5, Dnop5, Nop5, unnamed" "IPR012974=NOP5, N-terminal, IPR002687=Nop domain, IPR012976=NOSIC" CG10206 16-Dec-15 2015_12 "ENSDARG00000058337(nop58),ENSDARG00000007204(wu:fb54a03)" YOR310C(NOP58) WBGene00020915(nol-5) ENSXETG00000022073(nol5) ENSMUSG00000026020(Nop58) ENSG00000055044(NOP58) " embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 11 , embryonic stage | stage 12 , embryonic stage | stage 6 , embryonic stage | stage 8 , adult stage | female " " midgut

, dorsal mesothoracic disc | restricted & posterior

, mesoderm

, embryonic brain

, eye-antennal disc

, ventral thoracic disc

, ovary

" embryonic stage | stage 4-16 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027363 Stam Signal transducing adaptor molecule http://flybase.net/reports/FBgn0027363.html protein_coding_gene "0043130=ubiquitin binding, 0008269=JAK pathway signal transduction adaptor activity" "0007259=JAK-STAT cascade, 0046425=regulation of JAK-STAT cascade, 0006886=intracellular protein transport, 2000274=regulation of epithelial cell migration, open tracheal system, 0051726=regulation of cell cycle, 0016197=endosomal transport, 0007427=epithelial cell migration, open tracheal system, 0048488=synaptic vesicle endocytosis, 0042060=wound healing, 0045743=positive regulation of fibroblast growth factor receptor signaling pathway, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0016322=neuron remodeling, 0007269=neurotransmitter secretion" 0033565=ESCRT-0 complex "signal transducing adaptor molecule, dstam, signal-transducing adaptor molecule, Signal transducer adaptor molecule, Stam1, stam, Signal Transducing Adaptor Molecule, STAM, CG6521, Dstam" "IPR018205=VHS subgroup, IPR008942=ENTH/VHS, IPR003903=Ubiquitin interacting motif, IPR002014=VHS domain, IPR001452=SH3 domain" CG6521 16-Dec-15 2015_12 "ENSDARG00000002127(stam),ENSDARG00000005318(stam2)" YHL002W(HSE1) WBGene00004109(stam-1) "ENSXETG00000001364(stam),ENSXETG00000021702(STAM2)" "ENSMUSG00000026718(Stam),ENSMUSG00000055371(Stam2)" "ENSG00000136738(STAM),ENSG00000115145(STAM2)" " embryonic stage | stage >=14 , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | syncytial blastoderm , embryonic stage | stage 11-13 , adult stage && oogenesis stage | stage >=S9 , embryonic stage | stage >=7 , adult stage && oogenesis stage | stage S9-10 " " ventral nerve cord | restricted

, oocyte

, ventral nerve cord | segmentally repeated

,

segmentally repeated , nurse cell

" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,lethal,recessive" "major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16,trichogen cell,dorsal air sac primordium,somatic clone,eye,photoreceptor cell,imaginal disc epithelial cell" FBgn0001185 her hermaphrodite http://flybase.net/reports/FBgn0001185.html FBgn0005174 protein_coding_gene "0046872=metal ion binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0022008=neurogenesis, 0019101=female somatic sex determination, 0007541=sex determination, primary response to X:A ratio, 0006357=regulation of transcription from RNA polymerase II promoter, 0007548=sex differentiation, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007530=sex determination" 0005634=nucleus "lethal (2) maternal, lethal(2)maternal, FBgn 1185, CG4694, l(2)mat" "IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG4694 16-Dec-15 2015_12 embryonic stage -- adult stage "viable,fertile,lethal,female,maternal effect,heat sensitive,sex-determination defective,recessive,wild-type,partially lethal - majority die,male,female semi-sterile,male fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,neuroanatomy defective" "sex comb,maternal effect,female terminalia,male terminalia,male abdominal 5 muscle,epiproct,abdominal sternite 6,embryonic/larval neuroblast,ganglion mother cell" FBgn0026415 Idgf4 Imaginal disc growth factor 4 http://flybase.net/reports/FBgn0026415.html FBgn0026066 protein_coding_gene "0008084=imaginal disc growth factor receptor binding, 0004568=chitinase activity" "0007444=imaginal disc development, 0005975=carbohydrate metabolic process, 0006032=chitin catabolic process" 0005576=extracellular region "CG1780, DmIDGF4, IDGF4, IDGF, IDGF-4, idgf4" "IPR013781=Glycoside hydrolase, catalytic domain, IPR001223=Glycoside hydrolase family 18, catalytic domain, IPR015520=Imaginal disc growth factor, IPR011583=Chitinase II, IPR017853=Glycoside hydrolase superfamily, IPR029070=Chitinase insertion domain" CG1780 16-Dec-15 2015_12 YDR371W(CTS2) " embryonic stage && larval stage , embryonic stage , larval stage | third instar , adult stage && oogenesis stage " " embryonic/larval fat body

, ventral furrow | vicinity of

, cephalic furrow | vicinity of

, embryonic/larval salivary gland

, larval brain

, larval optic lobe

, ring gland

, oocyte

, embryonic/larval tracheal system

, amnioproctodeal invagination | vicinity of

, yolk

, nurse cell

, imaginal disc

, lymph gland

" "viable,fertile" FBgn0021776 mira miranda http://flybase.net/reports/FBgn0021776.html protein_coding_gene "0005515=protein binding, 0003779=actin binding, 0017022=myosin binding" "0008298=intracellular mRNA localization, 0008595=anterior/posterior axis specification, embryo, 0045167=asymmetric protein localization involved in cell fate determination, 0007317=regulation of pole plasm oskar mRNA localization, 0007402=ganglion mother cell fate determination, 0055059=asymmetric neuroblast division, 0008105=asymmetric protein localization, 0030162=regulation of proteolysis, 0007405=neuroblast proliferation, 0048477=oogenesis, 0007400=neuroblast fate determination, 0072697=protein localization to cell cortex" "0045178=basal part of cell, 0016324=apical plasma membrane, 0045177=apical part of cell, 0005938=cell cortex, 0009925=basal plasma membrane, 0005737=cytoplasm, 0045180=basal cortex, 0045179=apical cortex, 0005813=centrosome, 0005818=aster" "Mira, mir, CG12249, Mir, Miranda, MIRA, MIR" CG12249 16-Dec-15 2015_12 " embryonic stage | stage >=8 , embryonic stage | stage 3 , embryonic stage | stage >=12 " " neuroblast

, ventral nerve cord | ventral

, sensory mother cell

, posterior midgut proper primordium

, embryonic brain

" " embryonic stage | stage >=8 , embryonic stage | cycle 1-9 , embryonic stage | stage >=12 , larval stage | third instar , embryonic stage , embryonic stage -- adult stage , embryonic stage | early , embryonic stage | cycle 10-11 " " sensory mother cell

, midgut primordium

, posterior midgut proper primordium

, organism

, neuroblast

, embryonic brain

, ventral nerve cord && neuroblast

, neuroblast

, ventral nerve cord | ventral

, ventral nerve cord && ganglion mother cell

, organism

, peripheral nervous system

" "neuroanatomy defective,lethal,recessive,tumorigenic,visible,homeotic,fertile" "glial cell,supernumerary,embryonic ganglion mother cell,commissure,neuroblast NB6-4 of thorax,embryonic/larval glial cell,neuroblast NB6-4,longitudinal connective,embryonic/larval neuron,ventral neurectoderm,embryonic neuroblast,embryonic/larval cell body glial cell,embryonic abdomen,ectopic,embryonic head,embryonic thorax,pole cell" FBgn0003483 spn-E spindle E http://flybase.net/reports/FBgn0003483.html FBgn0004883 protein_coding_gene "0004386=helicase activity, 0008186=RNA-dependent ATPase activity, 0003676=nucleic acid binding, 0003724=RNA helicase activity, 0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0046872=metal ion binding" "0048477=oogenesis, 0030423=targeting of mRNA for destruction involved in RNA interference, 0007315=pole plasm assembly, 0001556=oocyte maturation, 0009949=polarity specification of anterior/posterior axis, 0007076=mitotic chromosome condensation, 0016246=RNA interference, 0030720=oocyte localization involved in germarium-derived egg chamber formation, 0046843=dorsal appendage formation, 0000335=negative regulation of transposition, DNA-mediated, 0009951=polarity specification of dorsal/ventral axis, 0008298=intracellular mRNA localization, 0006403=RNA localization, 0009994=oocyte differentiation, 0006342=chromatin silencing, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0010529=negative regulation of transposition, 0007294=germarium-derived oocyte fate determination, 0030717=karyosome formation, 0045892=negative regulation of transcription, DNA-templated, 0045451=pole plasm oskar mRNA localization, 0007317=regulation of pole plasm oskar mRNA localization" "0043186=P granule, 0005634=nucleus, 0005737=cytoplasm" "spn E, SpindleE, spindle-E, fs(3)hls, CG3158, spindleE, spin-E, hes, Homeless, female sterile(3)homeless, Spindle E, spn-E/hls, fs(1)hls, Spn-E, homeless, spnE, Spindle-E (homeless), hls, homeless/spindle-E, SPN-E, SpnE, HOMELESS, Spindle-E" "IPR015880=Zinc finger, C2H2-like, IPR002999=Tudor domain, IPR011545=DEAD/DEAH box helicase domain, IPR007087=Zinc finger, C2H2, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR007502=Helicase-associated domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR001650=Helicase, C-terminal" CG3158 16-Dec-15 2015_12 ENSXETG00000023069(TDRD9) ENSMUSG00000054003(Tdrd9) ENSG00000156414(TDRD9) " adult stage && oogenesis stage , oogenesis stage && adult stage | female , embryonic stage | early " " nurse cell

, germarium

, female germline stem cell

, ovary

,

ubiquitous " "suppressor of variegation,female sterile,female sterile germline-dependent,meiotic cell cycle defective,recessive,sterile,male fertile,male sterile,fertile,partially,lethal,polyphasic,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,dominant,viable" "meiosis & nuclear chromosome,P granule,oocyte,egg chamber,dorsal appendage,microtubule,germline clone,karyosome,synaptonemal complex,germline cyst,egg,dorsal,meiosis & nuclear chromosome | male,spermatocyte" DRSC17064 K -0.598062282 0.232337059 -0.238993792 -0.329629295 -0.36659883 -1.610703376 FBgn0016984 sktl skittles http://flybase.net/reports/FBgn0016984.html "FBgn0010601, FBgn0015387" protein_coding_gene 0016308=1-phosphatidylinositol-4-phosphate 5-kinase activity "0071711=basement membrane organization, 0034613=cellular protein localization, 0046488=phosphatidylinositol metabolic process, 0007286=spermatid development, 0016310=phosphorylation, 0007422=peripheral nervous system development, 0048102=autophagic cell death, 0035071=salivary gland cell autophagic cell death, 0008103=oocyte microtubule cytoskeleton polarization, 0042070=maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification, 0030866=cortical actin cytoskeleton organization" "0016324=apical plasma membrane, 0005938=cell cortex, 0005886=plasma membrane, 0005634=nucleus, 0035323=male germline ring canal" "fam, phosphatidylinositol 4-phosphate 5-kinase, 25/17, l(2)05475, l(2)k12405, PIP5K 57B6, fata morgana, ski, CG9985, type I phosphatidylinositol 4-phosphate 5-kinase, PIP5K, PIP5-kinase, Skittles, Sktl" "IPR027484=Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR002498=Phosphatidylinositol-4-phosphate 5-kinase, core, IPR016034=Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup, IPR023610=Phosphatidylinositol-4-phosphate 5-kinase, IPR027483=Phosphatidylinositol-4-phosphate 5-kinase, C-terminal" CG9985 16-Dec-15 2015_12 "ENSDARG00000009442(si:ch211-243a15.1),ENSDARG00000024642(zgc:158838),ENSDARG00000006508(zgc:92316),ENSDARG00000002614(pip5k1a),ENSDARG00000044295(pip5k1b)" YDR208W(MSS4) WBGene00004087(ppk-1) "ENSXETG00000019412(pip5k1a),ENSXETG00000006418(PIP5K1C)" "ENSMUSG00000034902(Pip5k1c),ENSMUSG00000028126(Pip5k1a),ENSMUSG00000024867(Pip5k1b)" "ENSG00000186111(PIP5K1C),ENSG00000143398(PIP5K1A),ENSG00000180764,ENSG00000107242(PIP5K1B)" " embryonic stage | stage 11-13 , embryonic stage | stage 5 , embryonic stage | stage 17 , spermatogenesis , embryonic stage | gastrula , larval stage | third instar , embryonic stage | stage 4-5 , embryonic stage | stage 13 , adult stage | female , oogenesis stage , embryonic stage | 0-24 hr , embryonic stage , embryonic stage | stage 12-13 , embryonic stage | stage 11 " " embryonic central nervous system | precursor

, procephalic neurogenic region

, embryonic central nervous system | restricted

, spermatocyte

, ventral furrow

, photoreceptor cell R8 | precursor

, embryonic/larval midgut

, mesoderm

, embryonic/larval hindgut

, morphogenetic furrow | anterior to

, nurse cell

,

ubiquitous , embryonic peripheral nervous system | precursor

, ectoderm

, embryonic/larval foregut | restricted

, oocyte

, embryonic/larval pharynx

, cephalic furrow

, embryonic/larval dorsal vessel

, embryonic/larval hindgut | restricted

, embryonic nervous system

, germarium | restricted

, embryonic/larval foregut

, imaginal disc

, embryonic/larval midgut | restricted

, larval brain

, pole cell

" "cytokinesis defective,germline clone,female sterile,lethal,cell shape defective,somatic clone,cell polarity defective,recessive,some die during immature adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte nucleus,germline clone,dorsal appendage,maternal effect,actin filament & oocyte | germ-line clone,yolk granule | germline clone,spermatid cyst,egg,follicle cell,somatic clone,endocytic vesiclenos.PG,yolk granulenos.PG,rhabdomereGMR.PF,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,imaginal disc,wing,wing & macrochaeta,ovary,nurse cell & nucleus,wing & macrochaetadpp.blk1,scutum & macrochaetadpp.blk1,macrochaeta,ectopic,scutum,wing & macrochaeta32B,scutum & macrochaeta32B" FBgn0003165 pum pumilio http://flybase.net/reports/FBgn0003165.html "FBgn0004871, FBgn0010759, FBgn0014132, FBgn0015529, FBgn0046414" protein_coding_gene "0003723=RNA binding, 0003730=mRNA 3'-UTR binding, 0000900=translation repressor activity, nucleic acid binding" "0007281=germ cell development, 0000288=nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, 0048477=oogenesis, 0042078=germ-line stem cell division, 0045892=negative regulation of transcription, DNA-templated, 0007616=long-term memory, 0045786=negative regulation of cell cycle, 0042059=negative regulation of epidermal growth factor receptor signaling pathway, 0007280=pole cell migration, 0050804=regulation of synaptic transmission, 0048149=behavioral response to ethanol, 0007067=mitotic nuclear division, 0048813=dendrite morphogenesis, 0001709=cell fate determination, 0008595=anterior/posterior axis specification, embryo, 0016477=cell migration, 0008582=regulation of synaptic growth at neuromuscular junction, 0060213=positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, 0045727=positive regulation of translation, 0008258=head involution, 0017148=negative regulation of translation, 0007268=synaptic transmission" "0031594=neuromuscular junction, 0061177=type Is terminal bouton, 0005635=nuclear envelope, 0005737=cytoplasm, 0061176=type Ib terminal bouton, 0097482=muscle cell postsynaptic density" "EP(3)0883, CG9763, ova, milord, bemused, pumillio, CG9755, anon-WO0172774.19, Pumillio, pumuckel, Pumilio, fs(3)02003, l(3)01688, pkl, PUM, ovarette, Pum, bem, ovt" "IPR016024=Armadillo-type fold, IPR011989=Armadillo-like helical, IPR001313=Pumilio RNA-binding repeat" CG9755 16-Dec-15 2015_12 "ENSDARG00000023145,ENSDARG00000061040(si:ch1073-351m12.1)" YLL013C(PUF3) WBGene00004245(puf-9) "ENSXETG00000008903(PUM2),ENSXETG00000012904(PUM1)" "ENSMUSG00000028580(Pum1),ENSMUSG00000020594(Pum2)" "ENSG00000134644(PUM1),ENSG00000055917(PUM2)" " embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S9 " " organism | 0-10% egg length

, ovary

,

ubiquitous , germarium

, border follicle cell

, pole cell

" " adult stage , adult stage && oogenesis stage " " central nervous system

, mushroom body

, female germline stem cell &&of germarium region 1

, cystoblast &&of germarium region 1

" "visible,recessive,lethal,memory defective,chemical sensitive,learning defective,viable,fertile,female sterile,neurophysiology defective,sterile,locomotor behavior defective,semidominant,reduced,uncoordinated,flight defective,partially lethal - majority die,neuroanatomy defective,short lived,wild-type,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect,somatic clone,heat sensitive" "macrochaeta,ovary,female germline stem cell,ovariole,nurse cell,oocyte,nurse cell ring canal,interfollicle cell,terminal filament,germline clone,spectrosome,neuromuscular junction,aCC neuron,RP2 motor neuron,wing vein,ectopic,metathoracic tergum,motor neuron,anterior fascicle & synapse,intersegmental nerve,Bolwig nerve,wing,eye,embryonic abdominal segment,embryonic head,maternal effect,embryo,posterior,germarium,mouth hooks,dendritic arborising neuron & dendrite | somatic clone,germline cell,somatic clone,pole cell,embryonic epidermis,embryonic abdomen,larval head,cephalopharyngeal skeleton,dorsal closure embryo,embryonic/larval neuromuscular junction,NMJ bouton,type I bouton,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,germ cell & germarium,egg chamber,germline cyst,gonad,dendritic arborising neuron & dendritic tree477,Kenyon cell,adult mushroom body,dendritic arborising neuron & dendritic tree5-78,antennal lobe neuroblast,wing margin" DRSC17038 I -1.841870045 0.111860137 -0.985658745 0.100696606 -0.645727979 -0.851432167 FBgn0261270 SelD "Selenide,water dikinase" http://flybase.net/reports/FBgn0261270.html "FBgn0020615, FBgn0021903, FBgn0046452, FBgn0046453, FBgn0065403" protein_coding_gene "0005524=ATP binding, 0004756=selenide, water dikinase activity" "0016260=selenocysteine biosynthetic process, 0007444=imaginal disc development, 0007005=mitochondrion organization, 0008284=positive regulation of cell proliferation, 0022008=neurogenesis, 2000378=negative regulation of reactive oxygen species metabolic process, 0008283=cell proliferation, 0006541=glutamine metabolic process" "selenophosphate synthetase 1, l(2)k12303, SeS, Dm SelD, dsps1, selenide,water dikinase, l(2)SH2 1599, ptuf1, patufet, SPS1, lethal (2) SH1599, selD, selD/sps1, CG8553, Dm-SelD, 142926_at, dSPS1, ptf1, anon-WO0172774.146, selD-like, Selenophosphate synthetase, l(2)SH1599, ptuf, anon-WO0172774.145" "IPR004536=Selenophosphate synthetase, IPR010918=AIR synthase-related protein, C-terminal domain, IPR016188=PurM-like, N-terminal domain" CG8553 16-Dec-15 2015_12 ENSDARG00000058292(sephs1) WBGene00012867(seld-1) ENSXETG00000009116(sephs1) "ENSMUSG00000026662(Sephs1),ENSMUSG00000049091(Sephs2)" "ENSG00000086475(SEPHS1),ENSG00000179918(SEPHS2)" " embryonic stage | stage >=14 , larval stage | third instar , pupal stage , embryonic stage | stage >=6 , embryonic stage , embryonic stage | stage >=13 , embryonic stage -- adult stage " " gastric caecum | primordium

, larval optic lobe

, adult brain

, ventral nerve cord

, imaginal disc

, midgut primordium

,

ubiquitous , mesoderm

, larval midgut

, larval brain

, embryonic central nervous system

" DRSC07549 IE -1.475439323 -1.963513335 -1.581539245 -0.653011735 -0.073868281 -0.055689444 FBgn0000251 cad caudal http://flybase.net/reports/FBgn0000251.html FBgn0082204 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0008284=positive regulation of cell proliferation, 0009948=anterior/posterior axis specification, 0007487=analia development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007377=germ-band extension, 0002807=positive regulation of antimicrobial peptide biosynthetic process, 0035215=genital disc development, 0007443=Malpighian tubule morphogenesis, 0007442=hindgut morphogenesis, 0007350=blastoderm segmentation, 0010004=gastrulation involving germ band extension, 0035224=genital disc anterior/posterior pattern formation, 0007379=segment specification" "0005634=nucleus, 0005737=cytoplasm" "38E.19, anon-WO2004063362.83, CG1759, Caudal, cd, S67, CAD, Cad" "IPR001356=Homeobox domain, IPR000047=Helix-turn-helix motif, IPR020479=Homeodomain, metazoa, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like" CG1759 16-Dec-15 2015_12 "ENSDARG00000036292(cdx4),ENSDARG00000058999(cdx1b)" "ENSXETG00000004589(AF417199.1),ENSXETG00000010282(cdx1)" "ENSMUSG00000029646(Cdx2),ENSMUSG00000024619(Cdx1),ENSMUSG00000031326(Cdx4)" "ENSG00000165556(CDX2),ENSG00000113722(CDX1)" " embryonic stage | 13 , adult stage && oogenesis stage , larval stage | third instar , embryonic stage | extended germ band , adult stage && oogenesis stage | stage S11-14 , embryonic stage | embryonic cycle 13 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | 16-18 hr , adult stage && oogenesis stage | stage S6-11 , adult stage | female , embryonic stage | stage 13 , embryonic stage | early , embryonic stage | syncytial blastoderm , egg stage | unfertilized egg , larval stage , embryonic stage | stage 17 , embryonic stage | embryonic cycle 13-14 , prepupal stage , embryonic stage | >=2-4 hr " "

ubiquitous , inclusive hindgut primordium

, egg chamber

, Malpighian tubule

, amnioproctodeal invagination

, posterior midgut proper primordium

, oocyte

,

anterior posterior gradient ,

posterior , organism | 10-20% egg length

, gonad

, embryonic/larval midgut

, nurse cell

, embryonic midgut | anterior posterior gradient

, organism | 10-60% egg length

, anal pad

, proctodeum

, genital disc | posterior

,

10-60% egg length , unfertilized egg

, embryonic/larval hindgut

, organism

" " embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | embryonic cycle 8-14 , embryonic stage | gastrula , larval stage | third instar , embryonic stage | embryonic cycle 9 , embryonic stage | embryonic cycle 14A , embryonic stage | embryonic cycle 12-14 , embryonic stage | extended germ band , oogenesis stage , embryonic stage | stage 11 , embryonic stage | embryonic cycle 14B , embryonic stage | late , embryonic stage | embryonic cycle 10-13 " " posterior embryonic midgut

, epidermis | posterior

,

0-50% egg length ,

anterior posterior gradient , pole cell

, male genital disc | restricted

, Malpighian tubule

,

0-55% egg length , posterior midgut proper primordium

, unfertilized egg

30-50% egg length , amnioproctodeal invagination

,

0-30% egg length ,

14-15% egg length , posterior embryonic/larval midgut

, inclusive hindgut primordium

, female genital disc | restricted

, germ band | posterior

, organism | 10-20% egg length

,

0-20% egg length ,

posterior , embryonic anal pad

, anal pad

" "viable,lethal,recessive,visible,somatic clone,melanotic mass phenotype,increased cell number,short lived,germline clone,maternal effect" "abdominal segment 8,abdominal segment 10,abdominal segment 11,abdominal segment 9,abdominal 11 anal tuft,anal pad,embryonic/larval hindgut,Malpighian tubule,embryonic abdominal segment 8,genital disc primordium,male analia,somatic clone,female analia,germline clone,embryonic head,melanotic mass,adult posterior midgut epithelium,head capsule,analia,ectopic,anal plate,adult hindgut,embryonic segment,maternal effect,embryonic abdominal segment" FBgn0011300 babo baboon http://flybase.net/reports/FBgn0011300.html "FBgn0004835, FBgn0015469, FBgn0021802" protein_coding_gene "0016361=activin receptor activity, type I, 0048185=activin binding, 0005524=ATP binding, 0004672=protein kinase activity, 0004674=protein serine/threonine kinase activity, 0004703=G-protein coupled receptor kinase activity, 0004702=receptor signaling protein serine/threonine kinase activity, 0005025=transforming growth factor beta receptor activity, type I" "0048666=neuron development, 0007179=transforming growth factor beta receptor signaling pathway, 0040018=positive regulation of multicellular organism growth, 0048813=dendrite morphogenesis, 0030513=positive regulation of BMP signaling pathway, 0006468=protein phosphorylation, 0008340=determination of adult lifespan, 0007476=imaginal disc-derived wing morphogenesis, 0007346=regulation of mitotic cell cycle, 0007165=signal transduction, 0007411=axon guidance, 0010862=positive regulation of pathway-restricted SMAD protein phosphorylation, 0009411=response to UV, 0032924=activin receptor signaling pathway, 0007455=eye-antennal disc morphogenesis, 0010507=negative regulation of autophagy, 0007405=neuroblast proliferation, 0016319=mushroom body development" "0048179=activin receptor complex, 0005886=plasma membrane" "l(2)44Fd, ATR-1, BABO, baboa, Activin Type I receptor, Gprk-3, Atr-1, Atf1, CG8224, Gprk3, Atr45A, Activin A receptor 45A, Atr-I, AtrI, atr-I, Babo, G protein-coupled receptor kinase 3, STK-E, Baboon, l(2)k16912, ATR-I, Bab" "IPR000333=Ser/Thr protein kinase, TGFB receptor, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site, IPR011009=Protein kinase-like domain, IPR003605=GS domain, IPR017441=Protein kinase, ATP binding site, IPR001245=Serine-threonine/tyrosine-protein kinase catalytic domain, IPR000472=Activin types I and II receptor domain" CG8224 16-Dec-15 2015_12 "ENSDARG00000042259(tgfbr1b),ENSDARG00000017494(tgfbr1a),ENSDARG00000018968(acvr1b),ENSDARG00000052142(LOC559222)" WBGene00004860(sma-6) "ENSXETG00000023394(tgfbr1),ENSXETG00000000572(acvr1b),ENSXETG00000010381(ACVR1C)" "ENSMUSG00000007613(Tgfbr1),ENSMUSG00000000532(Acvr1b),ENSMUSG00000026834(Acvr1c)" "ENSG00000106799(TGFBR1),ENSG00000135503(ACVR1B),ENSG00000123612(ACVR1C)" " embryonic stage | 0-3 hr , adult stage | female , embryonic stage , adult stage && oogenesis stage | stage S10-11 , larval stage | third instar , embryonic stage -- adult stage " " nurse cell

, imaginal disc

, oocyte

" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,visible,dominant,neuroanatomy defective,mitotic cell cycle defective,germline clone,somatic clone,wild-type,developmental rate defective,decreased cell number,phototaxis defective,size defective,cell growth defective,viable,long lived,flight defective,progressive" "embryonic/larval brain,wing,head capsule,larva,anal pad,embryonic/larval anterior spiracle,imaginal disc,wing disc,optic lobe,axon & photoreceptor cell,embryonic brain,intersegmental nerve,abdominal segmental nerve,embryonic/larval neuromuscular junction,transverse nerve,brain,axon & photoreceptor cell R7,axon & photoreceptor cell R8,medulla,lamina,optic cartridge,medulla neuropil,medulla neuropil glial cell,lamina anlage glial cell,embryonic/larval optic lobe,medulla forming neuroblast,cell body rind of medulla,ganglion mother cell & larval optic lobe,lamina anlage,larval inner optic anlage,larval outer optic anlage,photoreceptor cell R7 & axon,photoreceptor cell R8 & axon,anterior pupal spiracle,leg,gamma-lobe & neuron | somatic clone,gamma-lobe & dendrite | somatic clone,germline clone,transmedullary neuron Tm20,somatic clone,photoreceptor cell R7,Kenyon cell,axon | somatic clone,dorsal cluster neuron & axon | somatic clone,dorsal cluster neuron & neurite | somatic clone,protocerebrum,fascicle,ellipsoid body,mushroom body gamma-lobe,distal medullary amacrine neuron Dm8,dorsal cluster neuron,adult mushroom body,embryonic/larval anal pad,olfactory neuron & axon,olfactory neuron & dendrite,antennal lobe & axon,calyx of mushroom body & axon,adult mushroom body & axon,adult antennal lobe projection neuron,persistent antennal lobe projection neuron,wing vein,eye,ommatidium,posterior compartment,wing vein | ectopic & wing | posterior compartmenten-e16E,wing blade,autophagic vacuoleMhc.PW,mesothoracic tergum,adult somatic muscle,progressive,lysosome | progressiveMhc.PW" FBgn0004456 mew multiple edematous wings http://flybase.net/reports/FBgn0004456.html "FBgn0028276, FBgn0040161" protein_coding_gene "0050840=extracellular matrix binding, 0004872=receptor activity, 0050839=cell adhesion molecule binding, 0046982=protein heterodimerization activity" "0007414=axonal defasciculation, 0048567=ectodermal digestive tract morphogenesis, 0035160=maintenance of epithelial integrity, open tracheal system, 0007475=apposition of dorsal and ventral imaginal disc-derived wing surfaces, 0007424=open tracheal system development, 0007608=sensory perception of smell, 0007432=salivary gland boundary specification, 0007160=cell-matrix adhesion, 0016337=single organismal cell-cell adhesion, 0007435=salivary gland morphogenesis, 0016203=muscle attachment, 0007155=cell adhesion, 0016477=cell migration, 0007426=tracheal outgrowth, open tracheal system, 0007411=axon guidance, 0033627=cell adhesion mediated by integrin, 0007427=epithelial cell migration, open tracheal system, 0007476=imaginal disc-derived wing morphogenesis, 0034446=substrate adhesion-dependent cell spreading, 0007015=actin filament organization, 0030154=cell differentiation, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0007431=salivary gland development, 0007494=midgut development" "0005925=focal adhesion, 0016324=apical plasma membrane, 0009925=basal plasma membrane, 0005887=integral component of plasma membrane, 0008305=integrin complex, 0016328=lateral plasma membrane" "Multiple edematous wings, alphaPS1, l(1)G0429, PS1, alphaPS integrin, alphaPS1 integrin, alpha[[PS1]] subunit of integrin, Position-specific-antigen-1alpha, alpha-PS1-integrin, PS1 integrin, aPS1, Integrin alphaPS1 subunit, alpha1Int, integrin alphaPS1 subunit, ItgaPS1, alpha1 integrin, PS1alpha, l(1)G0443, alpha integrin, integrin alphaPS1, PSalpha1, CG1771, CT5254, alpha-PS1, multiple edematous wing, alpha[[PS1]], Position-specific-1 antigen" "IPR013649=Integrin alpha-2, IPR000413=Integrin alpha chain, IPR013519=Integrin alpha beta-propellor, IPR013517=FG-GAP repeat, IPR018184=Integrin alpha chain, C-terminal cytoplasmic region, conserved site" CG1771 16-Dec-15 2015_12 "ENSDARG00000042282(itga6),ENSDARG00000069946(itga6b),ENSDARG00000056018(im:6912374),ENSDARG00000012824" WBGene00002081(ina-1) "ENSXETG00000021920(),ENSXETG00000007527(ITGA6)" "ENSMUSG00000025348(Itga7),ENSMUSG00000027111(Itga6),ENSMUSG00000001507(Itga3)" "ENSG00000135424(ITGA7),ENSG00000091409(ITGA6),ENSG00000005884(ITGA3)" " larval stage | third instar , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 11-12 " " adepithelial cell of dorsal mesothoracic disc

, posterior embryonic/larval midgut

, dorsal mesothoracic disc

, embryonic central nervous system

, peripodial epithelium

, tracheal pit

, ectoderm

, embryonic salivary gland

, anterior embryonic/larval midgut

" "lethal - all die before end of larval stage,recessive,some die during larval stage,viable,fertile,lethal,partially lethal - majority die,male,female,neuroanatomy defective,somatic clone,visible,heat sensitive" "filamentous actin | somatic clone,presumptive embryonic salivary gland,retina,somatic clone,wing,presumptive embryonic/larval digestive system,extended germ band embryo,midgut constriction,embryonic/larval midgut,fascicle,embryonic/larval visceral branch,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,intersegmental nerve,segmental nerve,muscle attachment site,anterior midgut primordium,salivary gland common duct primordium,embryonic/larval salivary gland,follicle cell,dorsal multidendritic neuron ddaC,somatic clone | third instar larval stage,dorsal wing blade,heat sensitive,photoreceptor,stage S14 oocyte,dorsal branch primordium" DRSC18971 E 0.244443446 0.617280166 -1.805192685 0.550427416 -0.086737417 -0.541777814 FBgn0000043 Act42A Actin 42A http://flybase.net/reports/FBgn0000043.html protein_coding_gene 0005200=structural constituent of cytoskeleton "0007010=cytoskeleton organization, 0000281=mitotic cytokinesis, 0006909=phagocytosis" "0035060=brahma complex, 0005875=microtubule associated complex, 0005884=actin filament" "Actin/BAP47, Act42a, F-actin, Actin, ACT2_DROME, BAP47, act 42A, C, Act, 42A, Act42, A, Actin42A, Actin-42A, AFFX-Dros-ACTIN_M_r_at, CG12051, 42A actin, actin, actin42A, act42A, actin42a" "IPR004001=Actin, conserved site, IPR004000=Actin family, IPR020902=Actin/actin-like conserved site" CG12051 16-Dec-15 2015_12 "ENSDARG00000037746(bactin1),ENSDARG00000037870(bactin2)" YFL039C(ACT1) "WBGene00000066(act-4),WBGene00000065(act-3),WBGene00000064(act-2)" "ENSXETG00000027641(actg1),ENSXETG00000025116(BC068217.1)" ENSMUSG00000029580(Actb) "ENSG00000184009(ACTG1),ENSG00000075624(ACTB)" " embryonic stage | blastoderm , embryonic stage " " embryonic/larval midgut

, gonad

, supraesophageal ganglion

, ventral nerve cord

, embryonic/larval proventriculus

" "lethal,partially lethal - majority die,visible" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,wing sensillum,external sensory organ" DRSC04835 IE -1.088303677 -3.479833708 -0.455146012 -1.65413146 0.596505723 1.478638891 FBgn0266581 pit pitchoune http://flybase.net/reports/FBgn0266581.html "FBgn0025140, FBgn0015236" protein_coding_gene "0003724=RNA helicase activity, 0004004=ATP-dependent RNA helicase activity, 0005524=ATP binding, 0003676=nucleic acid binding" "0008283=cell proliferation, 0016049=cell growth" "0005634=nucleus, 0005730=nucleolus" "hel93F, Pit, Helicase at 93F, CG6375, PIT, Hel93F, DmRH15, unnamed" "IPR001650=Helicase, C-terminal, IPR025313=Domain of unknown function DUF4217, IPR011545=DEAD/DEAH box helicase domain, IPR014014=RNA helicase, DEAD-box type, Q motif, IPR014001=Helicase superfamily 1/2, ATP-binding domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase" CG6375 16-Dec-15 2015_12 ENSDARG00000030789(ddx18) YMR290C(HAS1) WBGene00015232(B0511.6) ENSMUSG00000001674(Ddx18) ENSG00000088205(DDX18) " embryonic stage | early , adult stage && oogenesis stage , embryonic stage | stage 16 , oogenesis stage | stage >= S4 && adult stage | female , larval stage , embryonic stage | stage 11 , embryonic stage | stage >=11 , embryonic stage | gastrula " "

ubiquitous , germarium

, Malpighian tubule

, egg chamber

, imaginal disc | ubiquitous

, anal plate

, anterior midgut proper primordium

, embryonic/larval salivary gland | precursor

, epithelial sheath &&of embryonic/larval midgut

, epithelial sheath &&of embryonic/larval hindgut

, gonadal sheath

, embryonic/larval midgut

, posterior midgut proper primordium

, mesoderm

" FBgn0005638 slbo slow border cells http://flybase.net/reports/FBgn0005638.html "FBgn0013451, FBgn0015734, FBgn0016064, FBgn0016065, FBgn0016066" protein_coding_gene "0046982=protein heterodimerization activity, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding" "0006355=regulation of transcription, DNA-templated, 0046427=positive regulation of JAK-STAT cascade, 0007298=border follicle cell migration, 0001708=cell fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter" 0005634=nucleus "fs(2)7, Slow border cells, CCAAT/enhancer binding protein, slobo, Dm-c/EBP, CG4354, fs(2)8, SLBO, DM8, fs(2)ry7, DmC/EBP, Slow Border Cells, DC/EBP, C/EBP, unnamed, fs(2)ry8, Slbo" "IPR004827=Basic-leucine zipper domain, IPR031106=CCAAT/enhancer-binding protein C/EBP" CG4354 16-Dec-15 2015_12 "ENSXETG00000018291(cebpa),ENSXETG00000012286(Q3SYP1_XENTR),ENSXETG00000004850(cebpd)" "ENSMUSG00000034957(Cebpa),ENSMUSG00000052435(Cebpe)" "ENSG00000184771,ENSG00000092067(CEBPE)" " adult stage && oogenesis stage | female , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10 , embryonic stage | 8-16 hr " " ovary

, border follicle cell

, centripetally migrating follicle cell

" " embryonic stage | 9-10 hr , embryonic stage | mid-late , adult stage && oogenesis stage | stage S9-10 , adult stage && oogenesis stage | stage S10 " " embryonic/larval anterior spiracle

, embryonic/larval midgut

, embryonic/larval proventriculus

, embryonic/larval hindgut

, embryonic/larval salivary gland

, border follicle cell

, epidermis

, centripetally migrating follicle cell

, embryonic/larval foregut

" "female sterile,recessive,cell migration defective,fertile,poor,developmental rate defective,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,female fertile,wild-type,visible,lethal - all die before end of pupal stage,some die during pupal stage" "border follicle cell,egg chamber,polar follicle cell,somatic clone,wing,egg chamber | oogenesis stage S10,border follicle cell | oogenesis stage S10" DRSC04716 IE 1.368389206 -1.83883004 2.0455141 -1.599451076 0.070126022 0.737347815 FBgn0028789 Doc1 Dorsocross1 http://flybase.net/reports/FBgn0028789.html protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0001158=enhancer sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0035294=determination of wing disc primordium, 0061327=anterior Malpighian tubule development, 0007507=heart development, 0001700=embryonic development via the syncytial blastoderm, 0006355=regulation of transcription, DNA-templated, 0010468=regulation of gene expression, 0035051=cardiocyte differentiation" 0005634=nucleus "Tb66F2, doc, Ect2, CG5133, TBX6, Dorsocross, dorsocross, Doc, doc1, Dm-DOC1" "IPR018186=Transcription factor, T-box, conserved site, IPR008967=p53-like transcription factor, DNA-binding, IPR002070=Transcription factor, Brachyury, IPR001699=Transcription factor, T-box" CG5133 16-Dec-15 2015_12 WBGene00006543(tbx-2) ENSXETG00000004260(TEgg048b09.1) ENSMUSG00000030699(Tbx6) " adult stage | male , embryonic stage--pupal stage , embryonic stage | cellular blastoderm " dorsal ectoderm anlage

" embryonic stage | stage 5-11 , embryonic stage | stage 5-15 , embryonic stage | stage 15-16 , embryonic stage , embryonic stage | stage 9-16 " " organism | dorso-lateral

, amnioserosa

, dorsal pouch

, abdominal lateral pentascolopidial chordotonal organ lch5

, cardioblast | subset

, procephalic neurogenic region

, mesoderm | restricted

, embryonic anterior Malpighian tubule

, parasegment && ectoderm && mesoderm | dorsal & restricted

" viable FBgn0030608 Lsd-2 Lipid storage droplet-2 http://flybase.net/reports/FBgn0030608.html protein_coding_gene 0005515=protein binding "0050995=negative regulation of lipid catabolic process, 0019915=lipid storage, 0051049=regulation of transport, 0006629=lipid metabolic process, 0031887=lipid particle transport along microtubule, 0007476=imaginal disc-derived wing morphogenesis, 0030730=sequestering of triglyceride" "0005811=lipid particle, 0005875=microtubule associated complex" "Lipid Storage Droplet protein 2, CG9057, lipid storage droplet 2, LSD-2, Lipid storage droplet 2, 145098_at, Lsd2, Perilipin2, DmPLIN2, LSP-2, PLIN2, LSD2, plin2, Lipid Storage Droplet 2 Gene, lipid storage droplet-2, perilipin" IPR004279=Perilipin CG9057 16-Dec-15 2015_12 "ENSXETG00000023101(adfp),ENSXETG00000024167()" " larval stage | third instar , embryonic stage | late , embryonic stage | stage 5 , embryonic stage | stage 13 , embryonic stage | stage 4 " " fat body

, fat body && midgut | anterior

, germline cell

, amnioserosa

, organism | ubiquitous " larval stage | third instar fat body

"viable,fertile,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "lipid particle | embryonic stage | maternal effect,fat body,lipid particle,embryonic/larval fat body,nurse cell,lipid particle | embryonic stage,lipid droplet & larval oenocyteppl.PP,mesothoracic tergum" FBgn0000826 png pan gu http://flybase.net/reports/FBgn0000826.html FBgn0024363 protein_coding_gene "0005524=ATP binding, 0004674=protein serine/threonine kinase activity" "0000278=mitotic cell cycle, 0007343=egg activation, 0006468=protein phosphorylation, 0007346=regulation of mitotic cell cycle" 1902554=serine/threonine protein kinase complex "fs(1)M2, Pan gu, PNG, EG:8D8.5, CG11420, Png, pan-gnu" "IPR011009=Protein kinase-like domain, IPR000719=Protein kinase domain, IPR008271=Serine/threonine-protein kinase, active site" CG11420 16-Dec-15 2015_12 " embryonic stage | 0-3 hr , adult stage | female " " egg stage | unfertilized egg , embryonic stage | 0-12 hr " unfertilized egg

"lethal,maternal effect,female sterile,viable,fertile,wild-type,mitotic cell cycle defective,meiotic cell cycle defective" "nuclear chromosome,nucleus,polar body nucleus,nucleus | embryonic stage,nucleus & unfertilized egg,nucleus | blastoderm stage | maternal effect,egg & nucleus,pronucleus,annulate lamellae" FBgn0261988 Gprk2 G protein-coupled receptor kinase 2 http://flybase.net/reports/FBgn0261988.html "FBgn0004834, FBgn0039847, FBgn0011677" protein_coding_gene "0004703=G-protein coupled receptor kinase activity, 0004674=protein serine/threonine kinase activity, 0005524=ATP binding" "0003384=apical constriction involved in gastrulation, 0043950=positive regulation of cAMP-mediated signaling, 0050830=defense response to Gram-positive bacterium, 0048601=oocyte morphogenesis, 0008277=regulation of G-protein coupled receptor protein signaling pathway, 0038032=termination of G-protein coupled receptor signaling pathway, 0007186=G-protein coupled receptor signaling pathway, 0045879=negative regulation of smoothened signaling pathway, 0002805=regulation of antimicrobial peptide biosynthetic process, 0007224=smoothened signaling pathway, 0008592=regulation of Toll signaling pathway, 0006468=protein phosphorylation, 0008589=regulation of smoothened signaling pathway, 0007474=imaginal disc-derived wing vein specification, 0007165=signal transduction" "0005737=cytoplasm, 0005886=plasma membrane" "nosh, 154978_at, Gprk-2, CG17998, gprk2" "IPR000239=GPCR kinase, IPR017441=Protein kinase, ATP binding site, IPR000719=Protein kinase domain, IPR016137=RGS domain, IPR011009=Protein kinase-like domain, IPR002290=Serine/threonine/dual specificity protein kinase, catalytic domain, IPR000961=AGC-kinase, C-terminal" CG17998 16-Dec-15 2015_12 "ENSDARG00000070460(LOC100330963),ENSDARG00000070448(zgc:153020),ENSDARG00000032157(LOC561288)" WBGene00001708(grk-1) "ENSXETG00000010230(GRK5),ENSXETG00000009005(gprk5),ENSXETG00000014715(grk4),ENSXETG00000007243(GRK6)" "ENSMUSG00000074886(Grk6),ENSMUSG00000003228(Grk5),ENSMUSG00000052783(Grk4)" "ENSG00000198055(GRK6),ENSG00000198873(GRK5),ENSG00000125388(GRK4)" " larval stage | third instar , oogenesis stage && adult stage | female , embryonic stage | early , embryonic stage " ovary

" oogenesis stage && adult stage | female , larval stage , adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage && adult stage " " oocyte

, dorsal mesothoracic disc

, Kenyon cell

, longitudinal connective

, adult head

, larval central nervous system

, larval corpus allatum

, adult central nervous system

,

ubiquitous , optic lobe

, germarium

, follicle cell

, mushroom body

, retina

, mushroom body | restricted

, ovary

, neuron

, mushroom body alpha-lobe

, nurse cell

, ellipsoid body

" DRSC16682 I -1.711341334 -0.622063111 -0.283934963 -0.032537066 0.304681386 0.75792917 FBgn0004893 bowl brother of odd with entrails limited http://flybase.net/reports/FBgn0004893.html "FBgn0022034, FBgn0014041" protein_coding_gene "0003676=nucleic acid binding, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0046872=metal ion binding" "0045944=positive regulation of transcription from RNA polymerase II promoter, 0007362=terminal region determination, 0045893=positive regulation of transcription, DNA-templated, 0007442=hindgut morphogenesis, 0016348=imaginal disc-derived leg joint morphogenesis, 0035220=wing disc development, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0045892=negative regulation of transcription, DNA-templated, 0048617=embryonic foregut morphogenesis, 0007480=imaginal disc-derived leg morphogenesis, 0048619=embryonic hindgut morphogenesis, 0046331=lateral inhibition" 0005634=nucleus "Su(tor)2-1, l(2)c, CG10021, odd skipped-related 2, 17-29-5, org2, Bowl, bowel" "IPR013087=Zinc finger C2H2-type/integrase DNA-binding domain, IPR007087=Zinc finger, C2H2, IPR015880=Zinc finger, C2H2-like" CG10021 16-Dec-15 2015_12 "ENSMUSG00000004500(Zfp324),ENSMUSG00000044296(Zfp879),ENSMUSG00000054967(Zfp647),ENSMUSG00000030443(Zfp583),ENSMUSG00000046185(Zfp84),ENSMUSG00000030386(Zfp606),ENSMUSG00000072623,ENSMUSG00000044807(Zfp354c),ENSMUSG00000078906,ENSMUSG00000078865,ENSMUSG00000058447(Zfp82),ENSMUSG00000062931(B230315N10Rik),ENSMUSG00000005267(Zfp287),ENSMUSG00000052675(Zfp112),ENSMUSG00000034538(Zfp418),ENSMUSG00000067430(Zfp763),ENSMUSG00000045757(Zfp764),ENSMUSG00000068962(Zfp114),ENSMUSG00000064141(Zfp69),ENSMUSG00000050855(BC027344),ENSMUSG00000031079(Zfp300),ENSMUSG00000046658(Zfp316),ENSMUSG00000069184(Zfp72),ENSMUSG00000042063(Zfp386),ENSMUSG00000030486,ENSMUSG00000067480,ENSMUSG00000057835(Zfp119),ENSMUSG00000074282(Zfp94),ENSMUSG00000078870(Gm14410),ENSMUSG00000048728(Zfp454),ENSMUSG00000031907(Zfp90),ENSMUSG00000064194(I1C0022H11Rik),ENSMUSG00000066829(Zfp810),ENSMUSG00000053347(4930432O21Rik),ENSMUSG00000062632,ENSMUSG00000003929(Zfp81),ENSMUSG00000062794(Zfp599),ENSMUSG00000053985(Zfp14),ENSMUSG00000060630(Zfp735),ENSMUSG00000055102(Zfp819),ENSMUSG00000057551(Zfp317),ENSMUSG00000063383(Gm4769),ENSMUSG00000033972(6330416L07Rik),ENSMUSG00000058093,ENSMUSG00000030823(9130019O22Rik),ENSMUSG00000060314(BC066028),ENSMUSG00000062101(BC031441),ENSMUSG00000078864(Gm14322),ENSMUSG00000047473(Zfp30),ENSMUSG00000074221(Zfp568),ENSMUSG00000020335(Zfp354b),ENSMUSG00000056014(A430033K04Rik),ENSMUSG00000051351(Zfp46),ENSMUSG00000066838(Zfp772),ENSMUSG00000071281,ENSMUSG00000054648(Zfp869),ENSMUSG00000074472(Zfp872),ENSMUSG00000071267,ENSMUSG00000052439(Zfp882),ENSMUSG00000058291(Zfp68),ENSMUSG00000020364(Zfp354a),ENSMUSG00000017667(Zfp334),ENSMUSG00000059475(Zfp426),ENSMUSG00000055240(Zfp101),ENSMUSG00000074283(Zfp109),ENSMUSG00000051499(Zfp786),ENSMUSG00000038630(Zkscan16),ENSMUSG00000054381(Zfp747),ENSMUSG00000055150(Zfp78),ENSMUSG00000074220(Zfp382),ENSMUSG00000055202(Zfp811),ENSMUSG00000069206(Zfp874),ENSMUSG00000055228(8430426H19Rik),ENSMUSG00000056383(AI987944),ENSMUSG00000078496(Gm13152),ENSMUSG00000059839(9630025I21Rik),ENSMUSG00000030604(4933426I21Rik),ENSMUSG00000002266(Zim1),ENSMUSG00000078861,ENSMUSG00000051037(Zfp455),ENSMUSG00000055835(Zfp1),ENSMUSG00000053390(C920016K16Rik),ENSMUSG00000078995(Zfp456),ENSMUSG00000058900(Rsl1),ENSMUSG00000056300,ENSMUSG00000078994(Zfp429),ENSMUSG00000053600(Zfp472),ENSMUSG00000071295,ENSMUSG00000056824(Zfp663),ENSMUSG00000024298(Zfp871),ENSMUSG00000057254(Zfp870),ENSMUSG00000074830,ENSMUSG00000050605(Zfp61),ENSMUSG00000054893(Zfp667),ENSMUSG00000078500,ENSMUSG00000063535(Zfp773),ENSMUSG00000071477(Zfp777),ENSMUSG00000052909,ENSMUSG00000056552(E130120F12Rik),ENSMUSG00000062116(5730403M16Rik),ENSMUSG00000057982(Zfp809),ENSMUSG00000060397(Zfp128),ENSMUSG00000055991(Zkscan5),ENSMUSG00000078872,ENSMUSG00000061532(Gm10103),ENSMUSG00000062519(Zfp398),ENSMUSG00000068551(Zfp467),ENSMUSG00000058638(Zfp110),ENSMUSG00000020491(2810021J22Rik),ENSMUSG00000045598" "ENSG00000174282(ZBTB4),ENSG00000177311(ZBTB38)" " embryonic stage | stage 5 , embryonic stage , embryonic stage | stage 8-12 , embryonic stage | stage 7-9 , larval stage | third instar , embryonic stage | stage 11 , embryonic stage | stage 8-11 , pupal stage , embryonic stage | stage 7 , embryonic stage | stage 7-12 , embryonic stage | >= 2 hr , embryonic stage | stage 9 , embryonic stage | stage 11-14 " " organism | 80-100% egg length

, organism | pair rule

, posterior embryonic/larval midgut

,

0-10% egg length , amnioproctodeal invagination

, organism | 0-10% egg length

, ventral thoracic disc | restricted

, cephalic furrow

, labral segment

, organism | 80% egg length & ventral

, cephalic furrow | anterior to

, stomodeum

, organism | 70% egg length & dorsal

, embryonic/larval hindgut

,

terminal , leg | restricted

,

segment polarity , anterior embryonic/larval midgut

, embryonic/larval foregut

, organism | 20-100% egg length

" "lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,semidominant,maternal effect,somatic clone,viable" "embryonic mandibular segment,embryonic maxillary segment,embryonic/larval hindgut,embryonic/larval proventriculus,joint,tarsal segment,embryonic large intestine,embryonic small intestine,embryonic rectum,lateral process,cephalopharyngeal skeleton,somatic clone,tarsal segment 2,tarsal segment 3,tarsal segment 4,metatarsus,pretarsus,abdominal 2 ventral denticle belt,abdominal 6 ventral denticle belt,embryonic hindgut,adult cuticle & leg | somatic clone,eye disc,peripodial epithelium & dorsal mesothoracic disc | somatic clone | first instar larval stage,eye-antennal disc,antenna,ectopic,eye,prescutum,embryonic dorsal epidermis,embryonic proventriculus,keyhole structure,sex comb,thorax,chaeta,supernumerary" DRSC00805 E 0.132752495 -0.020690858 0.10548997 -1.875326317 0.192595915 0.752246115 FBgn0039175 ë_-PheRS Phenylalanyl-tRNA synthetase ë_ subunit http://flybase.net/reports/FBgn0039175.html protein_coding_gene "0002161=aminoacyl-tRNA editing activity, 0004826=phenylalanine-tRNA ligase activity, 0005524=ATP binding, 0000287=magnesium ion binding, 0003723=RNA binding" 0006432=phenylalanyl-tRNA aminoacylation 0009328=phenylalanine-tRNA ligase complex CG5706 "IPR005147=tRNA synthetase, B5-domain, IPR020825=Phenylalanyl-tRNA synthetase, B3/B4, IPR004531=Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic, IPR009061=Putative DNA-binding domain, IPR005146=B3/B4 tRNA-binding domain" CG5706 16-Dec-15 2015_12 ENSDARG00000016864(farsb) YLR060W(FRS1) WBGene00001498(fars-3) ENSXETG00000002934(farslb) ENSMUSG00000026245(Farsb) ENSG00000116120(FARSB) "lethal,female sterile" FBgn0262760 Mst77Y-11ë¬ Male-specific pseudogene 77Y 11 http://flybase.net/reports/FBgn0262760.html pseudogene_attribute 16-Dec-15 2015_12 FBgn0262870 axo axotactin http://flybase.net/reports/FBgn0262870.html "FBgn0261546, FBgn0026729, FBgn0035564, FBgn0052234, FBgn0035566, FBgn0035562" protein_coding_gene 0004867=serine-type endopeptidase inhibitor activity "0019226=transmission of nerve impulse, 0008038=neuron recognition" 0005576=extracellular region "CG13717, CG32234, CG43225, CT1277, CG42664, CG18296, CG13715" "IPR001791=Laminin G domain, IPR013320=Concanavalin A-like lectin/glucanase domain, IPR000742=EGF-like domain, IPR002223=Pancreatic trypsin inhibitor Kunitz domain, IPR013032=EGF-like, conserved site" CG43225 16-Dec-15 2015_12 WBGene00002174(itx-1) " embryonic stage | stage >=13 , larval stage " " medial intersegmental nerve root glial cell

, glial cell | subset

, interface glial cell

, larval central nervous system

segmentally repeated , embryonic central nervous system

segmentally repeated " embryonic stage " embryonic peripheral nervous system | restricted

, ventral nerve cord

, embryonic brain

, neuron

" FBgn0030897 Frq1 Frequenin 1 http://flybase.net/reports/FBgn0030897.html FBgn0004120 protein_coding_gene "0005509=calcium ion binding, 0008048=calcium sensitive guanylate cyclase activator activity" "0007268=synaptic transmission, 0007528=neuromuscular junction development, 0046928=regulation of neurotransmitter secretion, 0007269=neurotransmitter secretion" 0045202=synapse "Frequentin, frq, Frequinin, HL-II, CG5744, Frq, frq1, frequenin 1, unnamed, Frequenin, frequenin" "IPR002048=EF-hand domain, IPR011992=EF-hand domain pair, IPR018247=EF-Hand 1, calcium-binding site, IPR028846=Recoverin family" CG5744 16-Dec-15 2015_12 "ENSDARG00000055229(ncs1a),ENSDARG00000054186(ncs1b)" YDR373W(FRQ1) WBGene00003563(ncs-1) ENSXETG00000001355(freq) ENSMUSG00000062661(Ncs1) ENSG00000107130(NCS1) " embryonic stage , adult stage , larval stage " " embryonic peripheral nervous system

, adult brain

, central nervous system

, synapse

, neuromuscular junction

, larval brain

, lamina

, neuropil

" "neuroanatomy defective,heat sensitive,viable,neurophysiology defective,locomotor behavior defective" "bouton,heat sensitive,motor neuron,embryonic/larval neuromuscular junction,type I bouton,NMJ bouton" FBgn0014861 Mcm2 Minichromosome maintenance 2 http://flybase.net/reports/FBgn0014861.html FBgn0011511 protein_coding_gene "0005524=ATP binding, 0003682=chromatin binding, 0003677=DNA binding, 0043138=3'-5' DNA helicase activity" "0006270=DNA replication initiation, 0046331=lateral inhibition, 0030261=chromosome condensation, 0006260=DNA replication, 0006267=pre-replicative complex assembly involved in nuclear cell cycle DNA replication, 0022008=neurogenesis, 0008283=cell proliferation" "0005656=nuclear pre-replicative complex, 0042555=MCM complex, 0005634=nucleus" "dMcm2, DmMcm2, PCR3, MCM2-7, unnamed, l(3)rL074, CG7538, DmeMCM2, dMCM2, MCM2_DROME, DmMCM2, MCM2, McM2" "IPR008045=DNA replication licensing factor Mcm2, IPR027925=MCM N-terminal domain, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR018525=Mini-chromosome maintenance, conserved site, IPR001208=MCM domain, IPR012340=Nucleic acid-binding, OB-fold, IPR031327=Mini-chromosome maintenance protein" CG7538 16-Dec-15 2015_12 ENSDARG00000015911(mcm2) YBL023C(MCM2) WBGene00003154(mcm-2) ENSXETG00000002059(mcm2) ENSMUSG00000002870(Mcm2) ENSG00000073111(MCM2) " embryonic stage | early , embryonic stage , embryonic stage | stage 8 " " central nervous system

, embryonic/larval digestive system

, embryonic peripheral nervous system

,

ubiquitous , Malpighian tubule

" "lethal,recessive,some die during immature adult stage,neuroanatomy defective,viable,visible" "central nervous system,imaginal disc,nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0028381 Decay Death executioner caspase related to Apopain/Yama http://flybase.net/reports/FBgn0028381.html protein_coding_gene 0004197=cysteine-type endopeptidase activity "0006915=apoptotic process, 0012501=programmed cell death, 0035069=larval midgut histolysis, 0006508=proteolysis" 0005737=cytoplasm "CC3, Cas3, death executioner caspase related to Apopain/Yama, Drosophila executioner caspase related to Apopain/Yama, caspase 3, Caspase-3, caspase-3 protein, CAS3, caspase-3, Caspase 3, CG14902, DECAY, cas3, Casp3, decay, Cleaved Caspase 3, Death executioner caspase related to Apopain/Yama, Decay" "IPR002138=Peptidase C14, caspase non-catalytic subunit p10, IPR029030=Caspase-like domain, IPR015917=Peptidase C14A, caspase precursor p45, core, IPR016129=Peptidase C14, ICE, catalytic subunit p20, active site, IPR001309=Peptidase C14, ICE, catalytic subunit p20, IPR011600=Peptidase C14, caspase domain" CG14902 16-Dec-15 2015_12 WBGene00000417(ced-3) " embryonic stage | stage >=13 , larval stage | third instar , embryonic stage | stage 1-7 , adult stage && oogenesis stage , embryonic stage -- adult stage " " embryonic/larval midgut

,

ubiquitous , oocyte

, nurse cell

, eye disc

, larval brain

, egg chamber

, embryonic/larval salivary gland

" "viable,fertile,visible,male semi-sterile" "trichogen cell,male accessory gland,ejaculatory duct,seminal vesicle" DRSC16930 EK -0.227542395 -0.01868415 1.045984036 1.566359268 -0.759995687 1.895748115 FBgn0004369 Ptp99A Protein tyrosine phosphatase 99A http://flybase.net/reports/FBgn0004369.html "FBan0002005, FBan0011517, FBgn0010251, FBgn0039661, FBgn0039662, FBgn0040621, FBgn0040622" protein_coding_gene "0004725=protein tyrosine phosphatase activity, 0005001=transmembrane receptor protein tyrosine phosphatase activity" "0007414=axonal defasciculation, 0008045=motor neuron axon guidance, 0006470=protein dephosphorylation, 0007415=defasciculation of motor neuron axon" "0005886=plasma membrane, 0030424=axon" "ptp99A, dptp99A, CG2005, CG11517, R-PTP 99A, CG11515, DPTP99A, CT6383, DPTP[[99A]], CG11516, PTP99A" "IPR029021=Protein-tyrosine phosphatase-like, IPR013783=Immunoglobulin-like fold, IPR016130=Protein-tyrosine phosphatase, active site, IPR007110=Immunoglobulin-like domain, IPR000242=PTP type protein phosphatase, IPR003961=Fibronectin type III, IPR000387=Tyrosine specific protein phosphatases domain, IPR003595=Protein-tyrosine phosphatase, catalytic" CG11516 16-Dec-15 2015_12 ENSXETG00000022735(PTPRZ1) "ENSG00000106278(PTPRZ1),ENSG00000144724(PTPRG)" " larval stage | first instar , embryonic stage | stage 12-14 , embryonic stage , embryonic stage | stage 12 , adult stage , embryonic stage && adult stage , embryonic stage&&adult stage , embryonic stage | stage >=13 , embryonic stage | early , larval stage " " RP1 neuron

, aCC neuron

, central nervous system | restricted

, adult head

, RP2 neuron

, pCC neuron

, VUM neuron

, embryonic central nervous system | segmentally repeated pattern

, imaginal disc

, RP3 neuron

" " embryonic stage | stage 12-16 , embryonic stage | stage 12-17 , embryonic stage | stage >=13 , embryonic stage | stage 12-14 , embryonic stage | stage >=12 , embryonic stage | stage 12 , embryonic stage , embryonic stage | stage 13-17 " " segmental nerve

, longitudinal connective

, intersegmental nerve

, embryonic central nervous system

, posterior commissure

, aCC neuron

, anterior commissure

, commissure

, RP2 neuron

, RP1 neuron

, supraesophageal ganglion

, pCC neuron

, RP3 neuron

, embryonic/larval trachea

, neuron

, ventral nerve cord

, central nervous system | restricted

" "viable,fertile,chemical sensitive" "intersegmental nerve,abdominal segmental nerve" DRSC14319 K 1.916851367 -0.487310118 FBgn0014143 croc crocodile http://flybase.net/reports/FBgn0014143.html FBgn0004894 protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding, 0003677=DNA binding, 0003690=double-stranded DNA binding, 0043565=sequence-specific DNA binding, 0008301=DNA binding, bending" "0000122=negative regulation of transcription from RNA polymerase II promoter, 0009888=tissue development, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0048513=organ development, 0009653=anatomical structure morphogenesis, 0007380=specification of segmental identity, head" "0005634=nucleus, 0005667=transcription factor complex" "FD1 transcription unit, FD1, fd1, forkhead domain 78E, Dmfd1, FoxC, fd78E, CG5069" "IPR011991=Winged helix-turn-helix DNA-binding domain, IPR018122=Fork head domain conserved site1, IPR001766=Fork head domain" CG5069 16-Dec-15 2015_12 "ENSDARG00000067822,ENSDARG00000055398(foxc1b)" WBGene00006853(unc-130) "ENSXETG00000000594(foxc1),ENSXETG00000016387(foxc2)" "ENSMUSG00000050295(Foxc1),ENSMUSG00000046714(Foxc2)" "ENSG00000054598(FOXC1),ENSG00000176692(FOXC2)" " embryonic stage | blastoderm , embryonic stage | stage 11 , embryonic stage | stage 17 , embryonic stage | stage 7 , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 7-13 , embryonic stage | stage 5 , embryonic stage | stage 5,6 " " stomodeum

, embryonic/larval pharynx | posterior

, intercalary segment

, mesoderm | posterior | restricted

, embryonic central nervous system

, embryonic/larval foregut

, labral segment

,

posterior | restricted , mesoderm | segmentally repeated

,

anterior | restricted " " embryonic stage | stage 5,6 , embryonic stage | stage 11 , embryonic stage | stage 9 , embryonic stage | stage 17 , embryonic stage | stage 7 , embryonic stage | stage 5 , embryonic stage | stage 7-13 " "

anterior | restricted , mesoderm | segmentally repeated

, mesoderm | posterior | restricted

, embryonic/larval pharynx | posterior

, stomodeum

, labral segment

, intercalary segment

,

posterior | restricted , embryonic/larval foregut

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,visible" "embryonic labral segment,embryonic antennal segment,embryonic intercalary segment,embryonic/larval esophagus,stomatogastric nervous system,embryonic/larval labral nerve,adult labral sense organ,dorsopharyngeal organ,pharyngeal monoscolopidial chordotonal organ,trichogen cell" FBgn0028554 x16 http://flybase.net/reports/FBgn0028554.html "FBgn0022271, FBgn0040511, FBgn0061658" protein_coding_gene "0003723=RNA binding, 0000166=nucleotide binding, 0008270=zinc ion binding, 0005515=protein binding, 0003729=mRNA binding" "0000381=regulation of alternative mRNA splicing, via spliceosome, 0008380=RNA splicing, 0000398=mRNA splicing, via spliceosome, 0031440=regulation of mRNA 3'-end processing, 0001178=regulation of transcriptional start site selection at RNA polymerase II promoter, 0006376=mRNA splice site selection, 0007399=nervous system development, 0010468=regulation of gene expression" "0071013=catalytic step 2 spliceosome, 0005681=spliceosomal complex, 0071011=precatalytic spliceosome, 0005634=nucleus" "l(2)k00230, d9G8, Xl6, anon-WO0118547.78, TN166, xl6, RBP1-like, x16, XL6, 2/30, dxl6, X16/9G8, Dx16, Dxl6, CG10203, 9G8, dx16" "IPR000504=RNA recognition motif domain, IPR012677=Nucleotide-binding alpha-beta plait domain, IPR001878=Zinc finger, CCHC-type" CG10203 16-Dec-15 2015_12 ENSDARG00000035325(zgc:77155) WBGene00004703(rsp-6) ENSXETG00000025300(sfrf7) ENSMUSG00000024097(Srsf7) ENSG00000115875(SRSF7) " embryonic stage | stage 11 , embryonic stage | stage 5-11 , larval stage | third instar , embryonic stage | stage 14-16 , adult stage && oogenesis stage " " ventral neurogenic region

,

ubiquitous , eye-antennal disc | restricted

, ventral thoracic disc | restricted

, embryonic brain

, dorsal mesothoracic disc | restricted

, nurse cell

, embryonic central nervous system

" "visible,lethal,recessive,viable,fertile" "eye,trichogen cell" FBgn0025525 bab2 bric a brac 2 http://flybase.net/reports/FBgn0025525.html "FBgn0012044, FBgn0035185" protein_coding_gene "0003680=AT DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding, 0005515=protein binding" "0006351=transcription, DNA-templated, 0007480=imaginal disc-derived leg morphogenesis, 0061040=female gonad morphogenesis, 0007455=eye-antennal disc morphogenesis, 0008585=female gonad development, 0006355=regulation of transcription, DNA-templated" "0005700=polytene chromosome, 0005634=nucleus, 0005701=polytene chromosome chromocenter" "bab-II, bric-a-brac, Bric a brac, BTB-protein-II, BtbII, Bric-a-brac 2, bab2, Bab2, BAB, bric-a-brac-2, bric a brac II, bric a brac, BTB-II, BAB2, Bric a brac II, bab, CG13911, bric-a-brac 2, bric-a-brac2, CG9102" "IPR011333=POZ domain, IPR007889=DNA binding HTH domain, Psq-type, IPR000210=BTB/POZ domain, IPR009057=Homeodomain-like" CG9102 16-Dec-15 2015_12 "ENSDARG00000061110(zbtb44),ENSDARG00000070864(bcl6a)" ENSXETG00000017921(ZBTB44) ENSG00000160877(NACC1) " prepupal stage , larval stage | third instar " " ovary | restricted

, ventral thoracic disc | restricted

" " prepupal stage | stage P1 , prepupal stage , larval stage | third instar stage 2 , larval stage | third instar " " ovary | restricted

, central nervous system | restricted

, larval central nervous system | restricted

, ventral thoracic disc | restricted

, female genital disc | restricted

, male genital disc | restricted

" "visible,dominant,male,body color defective,recessive,female,female sterile,female fertile,partially lethal - majority die,lethal,viable,cell number defective,cell migration defective" "adult cuticle & abdominal segment 5 | male,adult cuticle & abdominal segment 6 | male,leg,ovary,abdominal tergite 5,female,abdominal tergite 6,ovariole,antenna,prothoracic tarsal segment 2,tarsal segment 4,tarsal segment 5,abdominal tergite 7,terminal filament,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,tergite,adult abdomen & cuticlep339,tarsal segment,wing,adult abdomen & cuticle30A,basal cylinder,arista,ectopic,haltere,wing hinge,wing disc,adult cuticle & abdominal segment | malepnr-MD237,abdominal sternite 6,male,abdominal sternite 7,abdominal sternite 6 & trichome | maleC-765,abdominal tergite 6 & trichome | maleC-765,abdominal sternite 6 & macrochaeta | maleC-765,abdominal tergite 6 & macrochaeta | maleC-765,mesothoracic tergum,terminal filament | prepupal stage,embryonic/larval dorsal vessel" FBgn0029082 hbs hibris http://flybase.net/reports/FBgn0029082.html "FBgn0033991, FBgn0064179" protein_coding_gene 0005515=protein binding "0042067=establishment of ommatidial planar polarity, 0007520=myoblast fusion, 0010950=positive regulation of endopeptidase activity, 0001751=compound eye photoreceptor cell differentiation, 0016202=regulation of striated muscle tissue development, 0007157=heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, 0061330=Malpighian tubule stellate cell differentiation, 0007156=homophilic cell adhesion via plasma membrane adhesion molecules, 0007220=Notch receptor processing, 0001745=compound eye morphogenesis, 0045747=positive regulation of Notch signaling pathway" "0005886=plasma membrane, 0016324=apical plasma membrane, 0005768=endosome, 0005913=cell-cell adherens junction, 0070765=gamma-secretase complex" "CG7449, inappropriate contacts, Hbs, CT22841, Hibris, icon, inappropriate contact" "IPR007110=Immunoglobulin-like domain, IPR003006=Immunoglobulin/major histocompatibility complex, conserved site, IPR013162=CD80-like, immunoglobulin C2-set, IPR013098=Immunoglobulin I-set, IPR003961=Fibronectin type III, IPR003599=Immunoglobulin subtype, IPR003598=Immunoglobulin subtype 2, IPR013783=Immunoglobulin-like fold" CG7449 16-Dec-15 2015_12 ENSDARG00000060758(nphs1l) WBGene00007750(syg-2) ENSXETG00000017513(NPHS1) ENSMUSG00000006649(Nphs1) ENSG00000161270(NPHS1) embryonic stage | stage 15 embryonic Malpighian tubule | restricted

"visible,recessive,planar polarity defective,viable,fertile,cell adhesion defective,somatic clone,partially lethal - majority die,some die during pupal stage" "eye,cone cell,microchaeta & adult thorax,interommatidial bristle,supernumerary,somatic clone,photoreceptor cell R3,photoreceptor cell R7,ommatidium,wing margin,notal microchaeta,adult Malpighian tubule Type II cell,presumptive embryonic/larval muscle system,embryonic myoblast,midgut chamber 1,visceral muscle primordium,visceral mesoderm,somatic mesoderm,myoblast,distal,microchaeta & scutumda.G32,microchaeta & scutum-537.4,dorsal,microchaeta & scutumpnr-MD237,inter-ommatidial cell,inter-ommatidial precursor cell,primary pigment cell,septate junction | somatic clone,cell-cell junction | somatic clone,eye photoreceptor cell,inter-ommatidial precursor cell | pupal stage P6,interommatidial bristle | pupal stage P6,wing hair" FBgn0003862 trx trithorax http://flybase.net/reports/FBgn0003862.html "FBgn0011040, FBgn0011340, FBgn0011443" protein_coding_gene "0004402=histone acetyltransferase activity, 0008157=protein phosphatase 1 binding, 0042800=histone methyltransferase activity (H3-K4 specific), 0003682=chromatin binding, 0043565=sequence-specific DNA binding, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0042803=protein homodimerization activity, 0008270=zinc ion binding, 0044212=transcription regulatory region DNA binding" "0048096=chromatin-mediated maintenance of transcription, 0032968=positive regulation of transcription elongation from RNA polymerase II promoter, 0007411=axon guidance, 0008354=germ cell migration, 0016573=histone acetylation, 0043966=histone H3 acetylation, 0016571=histone methylation, 2001020=regulation of response to DNA damage stimulus, 0051568=histone H3-K4 methylation" "0005875=microtubule associated complex, 0005700=polytene chromosome, 0044665=MLL1/2 complex, 0005634=nucleus, 0035097=histone methyltransferase complex, 0000123=histone acetyltransferase complex, 0008023=transcription elongation factor complex" "tqrx, R-bx, l(3)s5452, TRITHORAX, CG8651, Rg-bx, DMTRXIII, Trithorax, trxI and trxII, l(3)j14A6, l(3)bx[v], TRX, Trx, l(3)j3A2, 4733, Trx-G, trx-g, Regulator of bithorax, NR0A5, 4720" "IPR001214=SET domain, IPR011011=Zinc finger, FYVE/PHD-type, IPR003889=FY-rich, C-terminal, IPR013083=Zinc finger, RING/FYVE/PHD-type, IPR001965=Zinc finger, PHD-type, IPR001841=Zinc finger, RING-type, IPR003616=Post-SET domain, IPR019787=Zinc finger, PHD-finger, IPR001628=Zinc finger, nuclear hormone receptor-type, IPR016569=Methyltransferase, trithorax, IPR003888=FY-rich, N-terminal" CG8651 16-Dec-15 2015_12 ENSXETG00000017567() ENSMUSG00000002028(Mll1) "ENSG00000118058(MLL),ENSG00000105663(MLL4)" " embryonic stage | early , embryonic stage , embryonic stage && larval stage && pupal stage , larval stage | third instar , adult stage | female , embryonic stage | stage 7-9 , embryonic stage | 11-15 hr , adult stage | male , embryonic stage | stage 5 , embryonic stage | 2-4hr , embryonic stage | stage 4 , embryonic stage -- adult stage , pupal stage , embryonic stage | late , embryonic stage | stage 4-8 " " embryonic central nervous system

, dorsal mesothoracic disc | posterior

,

ubiquitous , head

, imaginal disc

, dorsal metathoracic disc | posterior

, mesoderm | presumptive

, mesoderm anlage

, supraesophageal ganglion

, eye-antennal disc

, ventral mesothoracic disc | posterior

,

pair rule , subesophageal ganglion

, antenno-maxillary complex

, ventral nerve cord

,

20-50% egg length , ventral nervous system

, labral segment

, organism | even pair rule

" " larval stage | third instar , embryonic stage , larval stage " " dorsal mesothoracic disc | posterior

, dorsal metathoracic disc | posterior

, embryonic/larval proventriculus

, embryonic/larval salivary gland

, eye-antennal disc

, embryonic/larval midgut

, embryonic/larval digestive system

, ventral mesothoracic disc | posterior

, Malpighian tubule

, embryonic central nervous system

, imaginal disc

, gastric caecum

, larval fat body | central & posterior

" "viable,fertile,lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage,increased cell death,heat sensitive,wild-type,dominant,homeotic,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,non-enhancer of variegation,enhancer of variegation,increased cell number,somatic clone,mitotic cell cycle defective,male,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage" "adult thorax,wing disc | third instar larval stage,prothoracic tibia,sex comb,prothoracic segment,haltere,metathoracic segment,metathoracic tibia,abdominal tergite 5,male,abdominal tergite 6,abdominal tergite 7,wing,eye,head,labellum,lateral,photoreceptor cell,somatic clone,eye disc,abdominal segment 6,wing vein,ectopic,embryonic/first instar larval cuticle,embryonic/larval brain,embryonic/larval midgut,abdominal segment 5,adult abdominal segment 5,adult abdominal segment 6,adult abdominal segment 7,midgut constriction 1,midgut constriction 2,denticle belt,metathoracic laterotergite,abdominal tergite 2,abdominal tergite 3,antenna,maxillary palpus,adult head,arista,anterior,ventral,ocellar bristle,ocellus,postvertical bristle,pupal cuticle & abdomen,abdominal tergite 1,epiproct,adult,abdominal tergite 4,male genitalia,sternite,spiracle,abdominal segment,gonad,precursor,adult abdominal segment 4,epidermis,embryonic/larval tracheal system,mesothoracic tergum" FBgn0003430 slp1 sloppy paired 1 http://flybase.net/reports/FBgn0003430.html FBgn0010610 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0003690=double-stranded DNA binding, 0008301=DNA binding, bending, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0008134=transcription factor binding, 0001158=enhancer sequence-specific DNA binding" "0002052=positive regulation of neuroblast proliferation, 0007380=specification of segmental identity, head, 0048665=neuron fate specification, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0016199=axon midline choice point recognition, 0009953=dorsal/ventral pattern formation, 0009792=embryo development ending in birth or egg hatching, 0007346=regulation of mitotic cell cycle, 0045665=negative regulation of neuron differentiation, 0042305=specification of segmental identity, mandibular segment, 0045787=positive regulation of cell cycle, 0001707=mesoderm formation, 0010468=regulation of gene expression, 0007350=blastoderm segmentation, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0009888=tissue development, 0006355=regulation of transcription, DNA-templated, 0060914=heart formation, 0007379=segment specification, 0051090=regulation of sequence-specific DNA binding transcription factor activity, 0007507=heart development, 0035058=nonmotile primary cilium assembly, 0008595=anterior/posterior axis specification, embryo" "0005634=nucleus, 0005667=transcription factor complex" "l(2)05965, slp-2, sloppy-paired-1, SLP, Slp1, CG16738, SLOPPY-PAIRED, sloppy pair, Sloppy-paired1, slp-1, Sloppy-paired, Sloppy-paired 1, Slp, Sloppy, SLP1, Sloppy paired 1, sloppy paired, FD6, slp, sloppy-paired 1, Sloppy paired, Dmslp1, FoxG, sko1, Slp-1, sloppy-paired" "IPR018122=Fork head domain conserved site1, IPR001766=Fork head domain, IPR011991=Winged helix-turn-helix DNA-binding domain" CG16738 16-Dec-15 2015_12 WBGene00001434(fkh-2) " embryonic stage , embryonic stage | stage >7 , embryonic stage | stage 4 , embryonic stage | stage 4 | late , embryonic stage | stage 6 , embryonic stage | stage >=13 , embryonic stage | stage 5 " "

segment polarity , mandibular segment

,

70-100% egg length , organism | pair rule

, intercalary segment

,

71-87% egg length & ventral , labral segment

, embryonic/larval proventriculus

, ventral nerve cord

, embryonic procephalic segment | lateral

,

70-81% egg length & dorsal , organism | even pair rule

, organism | gap

" " embryonic stage | stage 8-11 , embryonic stage | stage 9-11 , embryonic stage | stage 5 , embryonic stage | stage 6,7 " " procephalic neurogenic region && embryonic antennal segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region &&of embryonic ocular segment | restricted

, organism | even pair rule

, procephalic neurogenic region && embryonic mandibular segment | restricted

, procephalic neurogenic region && labral segment | restricted

, tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

, procephalic neurogenic region && intercalary segment | restricted

,

segment polarity " "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,segment polarity phenotype,cell migration defective,viable,visible,body color defective" "cuticle,denticle belt,lateral process,ventral arm of lacinia,hypostomal sclerite,embryonic/larval dorsal vessel,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast NB4-2,neuroblast NB5-3,neuroblast NB3-5,neuroblast NB5-6,embryonic labial segment,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,embryonic/first instar larval cuticle & mesothoracic segment,head,embryonic head,mandibular segment,labial segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,visceral mesoderm,longitudinal visceral muscle primordium | embryonic stage 12,trichogen cell,mesothoracic tergum" FBgn0010433 ato atonal http://flybase.net/reports/FBgn0010433.html protein_coding_gene "0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000981=sequence-specific DNA binding RNA polymerase II transcription factor activity, 0046982=protein heterodimerization activity" "0007455=eye-antennal disc morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007460=R8 cell fate commitment, 0016360=sensory organ precursor cell fate determination, 0007605=sensory perception of sound, 0000187=activation of MAPK activity, 0001745=compound eye morphogenesis, 0048801=antennal joint morphogenesis, 0045465=R8 cell differentiation, 0048800=antennal morphogenesis, 0007438=oenocyte development, 0001748=optic lobe placode development, 0007420=brain development, 0007423=sensory organ development, 0045433=male courtship behavior, veined wing generated song production, 0007224=smoothened signaling pathway, 0048666=neuron development, 0008038=neuron recognition, 0016330=second mitotic wave involved in compound eye morphogenesis, 0007422=peripheral nervous system development, 0048813=dendrite morphogenesis, 0007399=nervous system development, 0001746=Bolwig's organ morphogenesis, 0045165=cell fate commitment, 0006355=regulation of transcription, DNA-templated, 0045464=R8 cell fate specification, 0007173=epidermal growth factor receptor signaling pathway" 0005634=nucleus "Ato, ato1, atona, CG7508, ato[Dm], At, ATO, Atonal, bHLHa10" "IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG7508 16-Dec-15 2015_12 " embryonic stage | stage 13 , larval stage | third instar , embryonic stage , larval stage--pupal stage " " embryonic central brain | restricted

, larval protocerebrum

, C1 chordotonal organ precursor cell

, chordotonal organ

, external sensory organ

, eye-antennal disc

, prothoracic chordotonal organ

, chordotonal organ &&of wing

, chordotonal organ of tegula

, morphogenetic furrow

, mesothoracic femoral chordotonal organ

, ventral thoracic disc

, inner proliferation zone

, chordotonal organ of scabellum

, Johnston's organ

" " embryonic stage | stage 9-11 , embryonic stage | stage 13 , adult stage , embryonic stage | stage 8-10 " " deuterocerebral neuroblast | subset

, embryonic ganglion mother cell

, protocerebral neuroblast | subset

, adult brain | restricted

, procephalic neurogenic region &&of embryonic antennal segment | restricted

, procephalic neurogenic region &&of embryonic ocular segment | restricted

, embryonic central brain | restricted

" "neuroanatomy defective,thermotaxis behavior defective,wild-type,recessive,somatic clone,touch sensitivity defective,visible,locomotor behavior defective,song defective,auditory perception defective,neurophysiology defective,partially lethal - majority die,visual behavior defective,behavior defective,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,viable" "eye,neurite,dendrite | adult stage,T neuron T4,T neuron T5,chordotonal organ of wing,supernumerary,ommatidium,photoreceptor cell R8,heat sensitive,photoreceptor cell,somatic clone,antennal segment 3 & fasciclep13),neuron of aristal sensillum,antennal lobe glomerulus,glial cell,antenna,antennal lobe,glial cell & antennap13),sensillum coeloconicum of antennal segment 3,glial cell & antennal lobep13),interneuron & antennal lobep13),pioneer neuron & adult antennal nerve & pupap13),abdominal lateral pentascolopidial chordotonal organ lch5,embryonic/larval oenocyte,sacculus,embryonic/larval oenocyte precursor,oenocyte primordium,C1 chordotonal organ precursor cell,third segment of antenna,Johnston organ,eye photoreceptor cell,eye photoreceptor cell & axon,morphogenetic furrow & filopodium | somatic clone,eye disc,sensillum coeloconicum,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,maxillary palp sensillum basiconicum,basiconic sensillum of sacculus,adult antennal nerve,chordotonal organ,scolopidial neuron,eye-antennal disc,morphogenetic furrow,embryonic/larval brain,adult brain,wing,cholinergic neuron,antenna & neuron,Bolwig organ,sensory mother cell,sensory mother cell & antennal disc,ocellus,interommatidial bristle,optic lobe,ommatidial precursor cluster,embryonic antennal sense organ,olfactory neuron & embryonic antennal sense organ,lch5 neuron,chordotonal organ precursor cell & ventral thoracic disc,mitotic cell cycle & eye disc | somatic clone,external sensory organ,ectopic,macrochaeta,photoreceptor cell R7,scutellar bristle,wing vein L3,scutum,adult thorax & macrochaeta109,abdominal sternite bristle,wing sensillum,campaniform sensillum of anterior crossvein,sensory mother cell & dorsal mesothoracic disc109,sensory mother cell & dorsal mesothoracic discptc-559.1,adult head,sensillum basiconicum,sensillum trichodeum,sensillum basiconicum of antennal segment 3,lobula,medulla,optic chiasma,abdominal basiconical sensillum dbd & larva & nerve terminal.PC,multidendritic neuron,macrochaeta & wing | ectopicdpp.blk1,chordotonal organ & wing | ectopicdpp.blk1,sternopleural bristle" FBgn0004170 sc scute http://flybase.net/reports/FBgn0004170.html "FBgn0003324, FBgn0003412, FBgn0026842" protein_coding_gene "0046982=protein heterodimerization activity, 0008134=transcription factor binding, 0005515=protein binding, 0001077=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0043565=sequence-specific DNA binding" "0007417=central nervous system development, 0007422=peripheral nervous system development, 0007549=dosage compensation, 0006355=regulation of transcription, DNA-templated, 0007399=nervous system development, 0007346=regulation of mitotic cell cycle, 0022416=chaeta development, 0007423=sensory organ development, 0007530=sex determination, 0007540=sex determination, establishment of X:A ratio, 0008407=chaeta morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007419=ventral cord development, 0006357=regulation of transcription from RNA polymerase II promoter, 0043066=negative regulation of apoptotic process, 0061382=Malpighian tubule tip cell differentiation, 0007400=neuroblast fate determination" "0005634=nucleus, 0005667=transcription factor complex" "AS-C T4sc, EG:198A6.1, Hairy-wing, Sc, AS-C T4, sis b, scute/sisterlessB, T4, DROACS2, l(1)1Ba, scalpha, Scute, sis-b, achaete-scute, asc, sisB, sisb, sisterless-b, CG3827, sc/T4, T4 AS-C, unnamed, Hw, scute-T4-transcript, ascT4, Achaete/Scute, scute/sisterless-b, bHLHc28, scute alpha" "IPR015660=Achaete-scute transcription factor-related, IPR011598=Myc-type, basic helix-loop-helix (bHLH) domain" CG3827 16-Dec-15 2015_12 "ENSDARG00000038386(ascl1a),ENSDARG00000009702(ascl1b)" WBGene00001958(hlh-14) "ENSMUSG00000020052(Ascl1),ENSMUSG00000009248(Ascl2)" "ENSG00000139352(ASCL1),ENSG00000183734(ASCL2)" " embryonic stage ,, larval stage | third instar , larval stage | third instar stage 2 , pupal stage , embryonic stage | cycle 9-13 , embryonic stage | 0-12hr " " labral segment

, neuroblast

, stomodeum

, proneural cluster

, dorsal mesothoracic disc | restricted

, neurogenic region

, ectoderm

, dorsal mesothoracic disc

, embryonic peripheral nervous system

, sensory mother cell

, posterior embryonic/larval midgut

, central nervous system

, adult trachea | precursor

, cleavage nucleus

, ventral midline

, cephalic furrow

, sensory organ cell

, procephalic neuroblast

, procephalic segment

" " embryonic stage , larval stage , larval stage | third instar , embryonic stage | stage 10-11 , embryonic stage | stage 9-11 , embryonic stage | stage 12-14 , embryonic stage -- adult stage " " embryonic/larval hindgut | restricted

, embryonic peripheral nervous system | restricted

, proneural cluster

, dorsal mesothoracic disc | restricted

, sensory mother cell

, embryonic central nervous system

, ectoderm

, procephalic neuroblast | subset

, protocerebral neuroblast | subset

, embryonic stomatogastric nervous system

, neuroblast

, ventral neurogenic region

, wing vein L1

, C1 chordotonal organ precursor cell

, dorsal mesothoracic disc

, procephalic neurogenic region | restricted

, deuterocerebral neuroblast | subset

" "viable,male,reduced,fertile,visible,male sterile,recessive,female sterile,female,lethal,wild-type,male fertile,female fertile,partially lethal - majority die,heat sensitive,sex-determination defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,female limited,partially lethal - majority live,mitotic cell cycle defective,sterile,lethal - all die before end of P-stage,some die during pharate adult stage,flightless" "humeral bristle,postvertical bristle,ocellar bristle,scutellar bristle,anterior orbital bristle,anterior notopleural bristle,presutural bristle,anterior postalar bristle,anterior supraalar bristle,posterior postalar bristle,macrochaeta,ectopic,mesothoracic tergum,wing,mesothoracic tarsal bristle,mesothoracic tarsal bristle longitudinal row 6.5,mesothoracic tarsal bristle longitudinal row 6,anterior dorsocentral bristle,middle orbital bristle,heat sensitive,chaeta,tergite,notal microchaeta,supernumerary,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,macrochaeta & leg,head,male,third segment of antenna,mesothoracic tergum & macrochaeta,posterior orbital bristle,posterior supraalar bristle,posterior notopleural bristle,dorsocentral bristle,proboscis & macrochaeta,upper humeral bristle,notopleural bristle,lower humeral bristle,orbital bristle,anterior vertical bristle,supraalar bristle,postalar bristle,sensillum campaniformium of dorsal radius Sc4d,vertical bristle,abdomen,abdominal sternite bristle,sternopleural bristle,anepisternum,posterior vertical bristle,microchaeta,anterior scutellar bristle,mesothoracic tarsal bristle longitudinal row 5.5,mesothoracic tarsal bristle longitudinal row 5,head bristle,posterior dorsocentral bristle,mechanosensory chaeta,posterior scutellar bristle,sternite,wing disc,sensory mother cell,sense organ,dorsal row & glial cell,ventral row & glial cell,anterior notal wing process sensillum campaniformium & glial cell,sensillum campaniformium of anterior crossvein & glial cell,sensillum campaniformium of dorsal radius & glial cell,mesothoracic metatarsus,wing sensillum,dorsal row,ventral row,eo neuron,tormogen cell,medial triple row,adult thoracic sensillum,external sensory organ,wing & external sensory organhs.PB,wing vein L2,multidendritic neuron,scutellum & microchaeta109,wing vein L3,scutum,sensory mother cell & dorsal mesothoracic disc109,sensory mother cell & dorsal mesothoracic discptc-559.1,mesothoracic tergum & macrochaeta | ectopic-C253,haltere,wing & macrochaetadpp.blk1,haltere sensillum,haltere & macrochaetadpp.blk1,macrochaeta & scutellum455.2,adult thorax & microchaetaap-md544,adult thorax & macrochaetaap-md544,mesothoracic tergum & macrochaeta | ectopicap-md544,dorsal medial muscle,chaeta | ectopic & mesothoracic tergumC-765" FBgn0046680 anon-38B.8 anon-38B.8 http://flybase.net/reports/FBgn0046680.html gene 38B.8 16-Dec-15 2015_12 FBgn0001150 gt giant http://flybase.net/reports/FBgn0001150.html protein_coding_gene "0042803=protein homodimerization activity, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0046982=protein heterodimerization activity, 0043565=sequence-specific DNA binding, 0000977=RNA polymerase II regulatory region sequence-specific DNA binding, 0000980=RNA polymerase II distal enhancer sequence-specific DNA binding, 0003700=sequence-specific DNA binding transcription factor activity, 0003677=DNA binding" "0007381=specification of segmental identity, labial segment, 0007411=axon guidance, 0010468=regulation of gene expression, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0007431=salivary gland development, 0007354=zygotic determination of anterior/posterior axis, embryo, 0007362=terminal region determination, 0044324=regulation of transcription involved in anterior/posterior axis specification, 0035271=ring gland development, 0008293=torso signaling pathway, 0008361=regulation of cell size, 0040015=negative regulation of multicellular organism growth, 0006909=phagocytosis, 0035289=posterior head segmentation" 0005634=nucleus "GT, l(1)3Aa, l(1)giant, CG7952, Giant, GIAN_DROME, EG:BACH7M4.5, DM17, Gt" "IPR029859=Protein giant, IPR004827=Basic-leucine zipper domain" CG7952 16-Dec-15 2015_12 "ENSXETG00000003160(DBP),ENSXETG00000004316(HLF)" "ENSMUSG00000022389(Tef),ENSMUSG00000003949(Hlf),ENSMUSG00000059824(Dbp)" "ENSG00000167074(TEF),ENSG00000108924(HLF),ENSG00000105516(DBP)" " embryonic stage | gastrulation , embryonic stage | extended germ band stage , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | embryonic cycle 13 , embryonic stage | embryonic cycle 12,13 , embryonic stage | embryonic cycle 12 " "

anterior{ + kni* } , anterior embryonic/larval midgut

{ + Kr* } ,

20-25% egg length{ 0 kni* } , labral segment

,

33-45% egg length{ 0 Kr* } ,

90-100% egg length , organism | 60-70% egg length

, organism | 70-80% egg length

, organism | 20-30% egg length

,

anterior{ 0 eve* } ,

anterior{ + hb* } ,

14-20% egg length{ 0 hb* } , organism | 60-80% egg length

, cephalic furrow

, organism | 50-90% egg length

, organism | 0-30% egg length

, organism | 90-100% egg length

,

20-40% egg length " " embryonic stage , embryonic stage | stage 5 , embryonic stage | embryonic cycle 12 , embryonic stage | embryonic cycle 13 " " maxillary segment

, organism | 90-100% egg length

, labrum

, ring gland

, organism | 20-40% egg length

, mandibular segment

, organism | 0-30% egg length

, organism | 60-80% egg length

, organism | 10-20% egg length

, organism | 60-70% egg length

, organism | 70-80% egg length

" "lethal,recessive,visible,viable,body size defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective" "larval salivary gland & embryo & nuclear chromosome,prothoracic gland innervating neuron PG-LP,prothoracic gland,nucleus | third instar larval stage,mesothoracic segment,metathoracic segment,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,embryonic/first instar larval cuticle,salivary gland,dorsal hair,ectopic,denticle belt,embryonic labial segment,embryonic prothoracic segment,dorsal ridge,abdominal 6 ventral denticle belt,hypostomal sclerite,embryonic abdominal segment,embryonic abdominal segment 6,embryonic abdominal segment 7,peripheral nervous system,chordotonal organ,lateral,larval abdominal segment 6,larval abdominal segment 7,embryonic stomatogastric nervous system,corpus cardiacum primordium,mouth hooks,hypophysis,embryonic/larval labial organ,larval head,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic head,embryonic abdominal segment 5,labial segment,thorax,anterior,abdominal segment 6,abdominal segment 7,larva" FBgn0004197 Ser Serrate http://flybase.net/reports/FBgn0004197.html "FBgn0003111, FBgn0003355" protein_coding_gene "0005509=calcium ion binding, 0005102=receptor binding, 0005154=epidermal growth factor receptor binding, 0005515=protein binding, 0005112=Notch binding" "0042689=regulation of crystal cell differentiation, 0036011=imaginal disc-derived leg segmentation, 0007219=Notch signaling pathway, 0016330=second mitotic wave involved in compound eye morphogenesis, 0007451=dorsal/ventral lineage restriction, imaginal disc, 0007431=salivary gland development, 0030718=germ-line stem cell maintenance, 0035167=larval lymph gland hemopoiesis, 0046331=lateral inhibition, 0007476=imaginal disc-derived wing morphogenesis, 0045746=negative regulation of Notch signaling pathway, 0035170=lymph gland crystal cell differentiation, 0035214=eye-antennal disc development, 0014009=glial cell proliferation, 0042688=crystal cell differentiation, 0007423=sensory organ development, 0007435=salivary gland morphogenesis, 0007436=larval salivary gland morphogenesis, 0048749=compound eye development, 0035017=cuticle pattern formation" "0009986=cell surface, 0030673=axolemma, 0005887=integral component of plasma membrane, 0016021=integral component of membrane, 0005886=plasma membrane, 0016324=apical plasma membrane" "CT18858, CG6127, dmSerrate, Bd, Ripped wing, serrate, std, ser, SER, mel(3)8, serratoid, Beaded, Rpw" "IPR001881=EGF-like calcium-binding domain, IPR026219=Jagged/Serrate protein, IPR009030=Insulin-like growth factor binding protein, N-terminal, IPR000152=EGF-type aspartate/asparagine hydroxylation site, IPR013032=EGF-like, conserved site, IPR001774=Delta/Serrate/lag-2 (DSL) protein, IPR000742=EGF-like domain, IPR018097=EGF-like calcium-binding, conserved site, IPR011651=Notch ligand, N-terminal domain, IPR006552=VWC out" CG6127 16-Dec-15 2015_12 "ENSDARG00000013168(jag1b),ENSDARG00000030289(jag1a),ENSDARG00000021389(jag2),ENSDARG00000014246(LOC566455)" ENSXETG00000002340(JAG1) "ENSMUSG00000002799(Jag2),ENSMUSG00000027276(Jag1)" "ENSG00000184916(JAG2),ENSG00000101384(JAG1)" " embryonic stage , adult stage | female , larval stage | third instar , embryonic stage | 2-4 hr , adult stage | male " " epidermis | stripes

, embryonic/larval foregut

, alula

, stomodeum

, embryonic/larval proventriculus

, embryonic/larval salivary gland

, trachea

, maxillary lobe

, mandibular segment

, embryonic salivary gland

, embryonic/larval hindgut

, embryonic/larval posterior spiracle

, central nervous system

, embryonic/larval hypopharynx

, supraesophageal ganglion

, labial segment

, labral segment

, embryonic/larval anterior spiracle

, embryonic/larval pharynx

, maxillary segment

, frontal head air sac | ventral

, dorsal mesothoracic disc

, anal pad

, epidermis

, telson

" " embryonic stage , larval stage | third instar " " embryonic/larval posterior spiracle

, stomodeum

, dorsal mesothoracic disc

, embryonic/larval pharynx

, embryonic/larval salivary gland

, supraesophageal ganglion

, mandibular segment

, epidermis

, frontal head air sac | ventral

, embryonic/larval foregut

, commissure

, labial segment

, alula

, embryonic/larval hindgut

, trachea

, embryonic/larval anterior spiracle

, labral segment

, epidermis | stripes

, maxillary segment

, anal pad

, embryonic/larval proventriculus

" "neuroanatomy defective,visible,viable,dominant,mitotic cell cycle defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal,cold sensitive,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,cell polarity defective,male fertile,size defective,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,body color defective" "interface glial cell,wing vein,wing margin,wing,distal,proneural cluster,optic lobe,glial cell,haltere,mesothoracic metatarsus,mesothoracic tarsal segment 2,metathoracic tarsal segment 2,prothoracic metatarsus,prothoracic tarsal segment 2,metathoracic metatarsus,crystal cell,embryonic head,mouth hooks,leg,tibia,femur,anterior,heat sensitive,eye,cold sensitive,adult heart,embryonic/larval anterior spiracle,papilla of larval anterior spiracle,wing disc,commissure,axon,dorsal closure embryo,denticle,cuticle,dorsal hair,dorsal compartment,somatic clone,joint,leg & joint,tarsal segment 1 & joint,tarsal segment 2 & joint,tarsal segment 3 & joint,tarsal segment 4 & joint,tarsal segment 5 & joint,denticle row 3 & abdominal 2 ventral denticle belt,denticle row 4 & abdominal 2 ventral denticle belt,denticle row 3 & abdominal 3 ventral denticle belt,denticle row 4 & abdominal 3 ventral denticle belt,denticle row 3 & abdominal 4 ventral denticle belt,denticle row 4 & abdominal 4 ventral denticle belt,denticle row 3 & abdominal 5 ventral denticle belt,denticle row 4 & abdominal 5 ventral denticle belt,denticle row 3 & abdominal 6 ventral denticle belt,denticle row 4 & abdominal 6 ventral denticle belt,denticle row 3 & abdominal 7 ventral denticle belt,denticle row 4 & abdominal 7 ventral denticle belt,denticle row 3 & abdominal 8 ventral denticle belt,denticle row 4 & abdominal 8 ventral denticle belt,dorsal pouch,dorsal bridge,lateral process,embryonic/larval proventriculus,embryonic/larval digestive system,hub cell,salivary gland imaginal ring,macrochaeta,ectopic,dorsal/ventral compartment boundary,actin filament & larval salivary gland,denticle row 3,denticle row 4,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,adult abdominal segment 7,procrystal cell,embryonic/larval salivary gland duct,presumptive embryonic/larval nervous system,embryonic epidermis,eye disc,dorsal,ventral,antenna,morphogenetic furrow,eye-antennal disc,supernumerary,medulla,ommatidium,interommatidial bristle,pigment cell,lens,eye photoreceptor cell,photoreceptor cell R7,ventral compartment,neuron,embryonic/larval proventriculus | embryonic stage,embryonic/larval digestive system | embryonic stage,presutural bristle & trichogen celll(3)31-1-31-1,anterior notopleural bristle & trichogen celll(3)31-1-31-1,posterior notopleural bristle & trichogen celll(3)31-1-31-1,anterior supraalar bristle & trichogen celll(3)31-1-31-1,posterior supraalar bristle & trichogen celll(3)31-1-31-1,anterior postalar bristle & trichogen celll(3)31-1-31-1,posterior postalar bristle & trichogen celll(3)31-1-31-1,anterior dorsocentral bristle & trichogen celll(3)31-1-31-1,posterior dorsocentral bristle & trichogen celll(3)31-1-31-1,anterior scutellar bristle & trichogen celll(3)31-1-31-1,microchaeta,scutum & macrochaeta & trichogen celll(3)31-1-31-1,tarsal segment,wing & macrochaetadpp.blk1,wing sensillum,macrochaeta & wingptc-559.1,dorsal row,ventral row,wing margin bristle,wing & macrochaeta | dorsalBx-MS1096,scutum & macrochaetaBx-MS1096,scutum,macrochaeta & wingh-540.3,tarsal segment 4,embryonic/larval lymph gland | larval stage,embryonic/larval lymph gland,rhabdomere,eye photoreceptor cell & eye disc | posterior-537.4,macrochaeta & thorax | supernumerary-537.4,eye photoreceptor cell & eye disch-H10,macrochaeta & scutellum | supernumerary | somatic clone | cell autonomous-109-68,macrochaeta & thorax | supernumerary | somatic cloneUbx.PdC,macrochaeta & thorax | somatic cloneUbx.PdC,trichogen cell,mesothoracic tergum" FBgn0000014 abd-A abdominal A http://flybase.net/reports/FBgn0000014.html protein_coding_gene "0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding" "0007507=heart development, 0009952=anterior/posterior pattern specification, 0007506=gonadal mesoderm development, 0007422=peripheral nervous system development, 0035224=genital disc anterior/posterior pattern formation, 0007494=midgut development, 0006915=apoptotic process, 0006355=regulation of transcription, DNA-templated, 0035053=dorsal vessel heart proper cell fate commitment, 0007399=nervous system development, 0008354=germ cell migration, 0048738=cardiac muscle tissue development, 0010002=cardioblast differentiation, 0007438=oenocyte development, 0048636=positive regulation of muscle organ development, 0007501=mesodermal cell fate specification, 0035225=determination of genital disc primordium, 0042694=muscle cell fate specification, 0007280=pole cell migration, 0014019=neuroblast development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0008406=gonad development, 0007385=specification of segmental identity, abdomen, 0048806=genitalia development, 0007400=neuroblast fate determination" "0005634=nucleus, 0005667=transcription factor complex" "abdominal-A, Hab, iab4, abda, abdominalA, abd_a, Abda, BX-C, abdA, Abdominal-A, Dmabda, iab-4, abdominal-a, AbdA, iab-3, Fab-3, Abd-A, Cbxd, Fab-4, iab, Contrabithoraxoid, infra-abdominal 4, iab2, l(3)89Ec, Hyperabdominal, unnamed, Ultraabdominal, ABD-A, infra-abdominal 2, abd-a, CG10325, iab3, infra-abdominal 3, infraabdominal, DmabdA, iab-5, AbdominalA, abd A, iab-2" "IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR022132=Homeobox protein, IPR001356=Homeobox domain, IPR020479=Homeodomain, metazoa" CG10325 16-Dec-15 2015_12 WBGene00011069(R06F6.6) ENSXETG00000021978(HOXB5) "ENSMUSG00000043342(Hoxd9),ENSMUSG00000036139(Hoxc9),ENSMUSG00000038227(Hoxa9),ENSMUSG00000020875(Hoxb9)" "ENSG00000105996(HOXA2),ENSG00000173917(HOXB2)" " embryonic stage , embryonic stage | stage 1-17 , embryonic stage | 2-4 hr , embryonic stage | stage 12 " parasegment 7--13

" embryonic stage | stage 15 , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 13-14 , larval stage , larval stage | third instar , embryonic stage | late , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 9-17 , embryonic stage | stage 10 , embryonic stage | stage 8 , embryonic stage | stage 7-12 " " pericardial cell

, ventral nerve cord

, neuroblast

, embryonic/larval trachea

, dorsal mesothoracic disc | retricted

, parasegment 13..15

{ + Abd-BM5 } , male genital disc | restricted

, epidermis

, embryonic dorsal vessel | posterior

, epidermis &&of gonad

, parasegment 14,15

, visceral mesoderm &&of parasegment 8--12

, amnioserosa

{ + Abd-BM1 } , ectoderm &&of parasegment 7--13

, gonad

, epidermis &&of ventral intersegmental neuron

, parasegment 14,15

{ + Abd-Biab9-tuh-3 } , visceral mesoderm &&of parasegment 8--12 &&of embryonic/larval midgut

, parasegment 7--13

, embryonic/larval spiracle

, chordotonal organ

, cardioblast && embryonic pericardial cell &&of embryonic abdominal segment 6--7

, embryonic heart

, parasegment 14,15

{ + Abd-B* } , abdominal 4--7 ventral intersegmental neuron

, visceral mesoderm

, female genital disc | restricted

, parasegment 7--13 , larval fat body | central

, parasegment 7--13

segmentally repeated , V neuron

, mesoderm &&of parasegment 8--12

, parasegment 7--13 &&of ventral nervous system

, cardioblast &&of embryonic abdominal segment 5,8

, alary cell | subset

, ventral nerve cord

segment A2-A7 , dorsal fibers of larval heart | lateral

, parasegment 13

{ + Abd-Biab9-x23-1 } , abdominal segment 1

, intersegmental nerve

, tracheal pit

, parasegment 7--12

" "homeotic,visible,dominant,viable,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,locomotor rhythm defective,wild-type,lethal,increased cell death,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,male sterile,female sterile,chemical sensitive,neuroanatomy defective" "abdominal segment,abdominal ventral denticle belt,embryonic/larval oenocyte precursor,lch5 neuron,embryonic thoracic segment,larval prothoracic segment,abdominal tergite 1,abdominal tergite 2,abdominal sternite 2,sternite,abdominal tergite 3,abdominal tergite 4,abdominal sternite 3,abdominal sternite 4,haltere,leg,wing,tergite,neuroblast,embryonic/larval somatic muscle,embryonic/larval tracheal system,,metathoracic segment,metathoracic leg,haltere disc,metathoracic leg disc,head,thorax,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,mesothoracic segment,chordotonal organ,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,embryo,parasegment 7,parasegment 8,parasegment 9,parasegment 10,parasegment 11,parasegment 12,parasegment 13,embryonic/larval central nervous system,embryonic epidermis,Wheeler's organ,abdominal sternite 5,gonad,abdominal sternite 6,ovary,female genitalia,heart primordium,cardioblast,embryonic/larval ostia,pole cell,genital disc primordium,gonadal sheath proper primordium,embryonic/larval heart,embryonic/larval aorta,dorsal closure embryo,germline cell,fat body/gonad primordium,abd-Aiab3-Uab4,Keilin's organ,embryonic/larval midgut,abdominal lateral pentascolopidial chordotonal organ,cuprophilic cell,midgut interstitial cell,embryonic/larval oenocyte,oviduct,testis,epidermis,lch5 ligament attachment cell,midgut constriction,abd-AMX1,Df(3R)Ubx109,A1-7 ventral acute muscle 1,how-24B,A2-7 ventral oblique muscle 6,A2-7 ventral transverse muscle 1,aorta primordium,embryonic dorsal vessel,embryonic visceral muscle,dorsal acute muscle,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic prothoracic segment,antenna,scutum,metathoracic laterotergite,NP5169,cephalopharyngeal skeleton,pharynx,embryonic/larval dorsal vessel,myofibril,cardiogenic mesoderm,metathoracic dorsal triscolopidial chordotonal organ dch3,embryonic tritocerebrum,embryonic/larval lymph gland,embryonic/larval pericardial cell,embryonic/larval posterior spiracle,abdominal 11 anal tuft,69B,wing margin,ppk.PG,EL neuron,arista,pretarsus,eye" FBgn0004595 pros prospero http://flybase.net/reports/FBgn0004595.html "FBgn0010941, FBgn0011397, FBgn0011437, FBgn0011497, FBgn0011499, FBgn0011504, FBgn0011507, FBgn0011515, FBgn0011524, FBgn0020281, FBgn0024917, FBgn0026852, FBgn0044730, FBgn0063172" protein_coding_gene "0001078=RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, 0003677=DNA binding, 0003700=sequence-specific DNA binding transcription factor activity" "0007406=negative regulation of neuroblast proliferation, 0070983=dendrite guidance, 0007400=neuroblast fate determination, 0042676=compound eye cone cell fate commitment, 0007619=courtship behavior, 0007423=sensory organ development, 0007405=neuroblast proliferation, 0070314=G1 to G0 transition, 0045664=regulation of neuron differentiation, 0007416=synapse assembly, 0048813=dendrite morphogenesis, 0007409=axonogenesis, 0007399=nervous system development, 0006909=phagocytosis, 0050909=sensory perception of taste, 0007402=ganglion mother cell fate determination, 0045165=cell fate commitment, 0008104=protein localization, 0007419=ventral cord development, 0001754=eye photoreceptor cell differentiation, 0008356=asymmetric cell division, 0000122=negative regulation of transcription from RNA polymerase II promoter, 0010001=glial cell differentiation, 0060385=axonogenesis involved in innervation, 0006355=regulation of transcription, DNA-templated, 1900180=regulation of protein localization to nucleus, 0010628=positive regulation of gene expression, 0001708=cell fate specification, 0007411=axon guidance, 0045676=regulation of R7 cell differentiation, 0008049=male courtship behavior, 0055060=asymmetric neuroblast division resulting in ganglion mother cell formation, 0050771=negative regulation of axonogenesis, 0007420=brain development, 0007465=R7 cell fate commitment, 0008285=negative regulation of cell proliferation, 0007422=peripheral nervous system development, 0010629=negative regulation of gene expression, 0042673=regulation of retinal cone cell fate specification, 0007417=central nervous system development, 0055059=asymmetric neuroblast division" "0005875=microtubule associated complex, 0005938=cell cortex, 0005886=plasma membrane, 0045178=basal part of cell, 0005634=nucleus, 0045179=apical cortex, 0045180=basal cortex" "unnamed, 0671/02, l(3)10419, l(3)rJ806, 0664/07, l(3)rO534, 0244/09, PROS-1, 1135/09, l(3)rI160, a la voile et a la vapeur, l(3)rL433, 0441/16, Prosp, l(3)j12C8, BcDNA:HL08040, DROPROSA, 1167/13, 0563/18, PROS, l(3)rK204, l(3)rH013, Pros, 0451/09, voila, DMPROSPER, 0763/13, 671/2, 1316/02, PROS-2, CG17228, 1135/07, l(3)rK137, pro, anon-WO0140519.15, 0585/13, Pro, l(3)j6E2, Voila, Prospero, 0989/01, 0320/10" "IPR023082=Homeo-prospero domain, IPR009057=Homeodomain-like" CG17228 16-Dec-15 2015_12 "ENSDARG00000055158(prox1),ENSDARG00000041952(prox2)" ENSXETG00000023176(PROX1) ENSMUSG00000010175(Prox1) " embryonic stage | stage 10 , embryonic stage , embryonic stage | 12-15 hr , embryonic stage | stage 6 , embryonic stage | stage 5-7 , embryonic stage | stage 9 , embryonic stage | blastoderm " " sensory mother cell

, glioblast

, embryonic peripheral nervous system

, neuroblast

, interface glial cell

, scolopidium

, ventral midline

, organism | pair rule

, thecogen cell &&of external sensory organ

, procephalic neurogenic region

, ganglion mother cell

, garland cell

, abdominal 1--7 lateral pentascolopidial chordotonal organ lch5

, scolopidial sheath cell

,

ubiquitous " " embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 11 " " ganglion mother cell &&of procephalic neurogenic region

, thecogen cell &&of external sensory organ

, ganglion mother cell &&of ventral nerve cord

, neuroblast MP2

, glial cell

, embryonic neuron

, scolopidium

, ganglion mother cell

" "lethal,recessive,courtship behavior defective,male,mating defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,temperature conditional,small body,taste perception defective,developmental rate defective,locomotor behavior defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,male sterile,some die during immature adult stage,somatic clone,viable,mitotic cell cycle defective,female fertile,visible,tumorigenic,decreased cell size,increased cell number" "embryonic/larval glial cell,anterior commissure,posterior commissure,longitudinal connective,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,axon,eye,axon & photoreceptor cell R7 | somatic clone,commissure,embryonic/larval neuromuscular junction,frontal ganglion,stomodeal nerve,esophageal ganglion 1,esophageal ganglion 2,photoreceptor cell R7,carbon dioxide sensitive neuron,ectopic,somatic clone,embryonic/larval brain,scutum & microchaeta,scutum & microchaeta & trichogen cell,scutum & microchaeta & tormogen cell,scutum & external sensory organ,peripheral nervous system,central nervous system,pCC neuron,aCC neuron,ventral midline,ventral nerve cord,RP2 motor neuron,U neuron,scutum & macrochaeta | somatic clone,interommatidial bristle,dendrite | dorsal | embryonic stage,dorsal,sensory neuron,peripheral glial cell,intersegmental nerve root glial cell,midline glial cell,filopodium & muscle cell,medial-most cell body glial cell,medial cell body glial cell,neuroblast NB6-4 of thorax,neuroblast NB7-4,trichogen cell,tormogen cell,scutum & macrochaeta,head bristle,head bristle & trichogen cell,head bristle & tormogen cell,head bristle & eo neuron,scutum & macrochaeta & eo neuron,scutum & microchaeta & eo neuron,interommatidial bristle & trichogen cell,interommatidial bristle & eo neuron,neuroblast,embryonic/larval neuroblast,ganglion mother cell,lens,adult olfactory receptor neuron Gr21a/63a,maxillary palp olfactory receptor neuron,embryonic ganglion mother cell,dendritic arborizing neuron,dendrite,chordotonal organ & axon | lateral,interface glial cell,neuron,motor neuron,hypodermal muscle of larval abdominal 4,hypodermal muscle of larval abdominal 5,cone cell,supernumerary,rhabdomere R7,primary pigment cell,scutum & external sensory organ & trichogen cell-P309,scutum & external sensory organ & tormogen cell-P309,antenna,microchaeta & antennal segment 3-P309,neuroblast NB7-3,morphogenetic furrow,scutum & macrochaeta-109-68,scutum & microchaeta-109-68,scutum & macrochaeta & trichogen cell-109-68,scutum & microchaeta & trichogen cell-109-68,interommatidial bristle & trichogen cell-109-68,scutum & macrochaeta & tormogen cell-109-68,scutum & microchaeta & tormogen cell-109-68,interommatidial bristle & tormogen cell-109-68,mesoderm,embryonic epidermis,neuroblast | larval stage,larval outer optic anlage,adult antennal lobe projection neuron DL1 adPN" FBgn0016797 fz2 frizzled 2 http://flybase.net/reports/FBgn0016797.html protein_coding_gene "0030165=PDZ domain binding, 0042813=Wnt-activated receptor activity, 0004888=transmembrane signaling receptor activity, 0017147=Wnt-protein binding" "0016055=Wnt signaling pathway, 0007165=signal transduction, 0007411=axon guidance, 0048675=axon extension, 0007186=G-protein coupled receptor signaling pathway, 0008045=motor neuron axon guidance, 0035206=regulation of hemocyte proliferation, 0050808=synapse organization, 0031290=retinal ganglion cell axon guidance, 0016477=cell migration, 0008585=female gonad development, 0007435=salivary gland morphogenesis, 0008407=chaeta morphogenesis, 0016201=synaptic target inhibition, 0008587=imaginal disc-derived wing margin morphogenesis, 0006898=receptor-mediated endocytosis" "0005634=nucleus, 0005887=integral component of plasma membrane, 0030139=endocytic vesicle, 0005770=late endosome, 0005886=plasma membrane, 0016021=integral component of membrane, 0005769=early endosome" "DFrizzled2, DFZ2, Frizzled-2, dfz2r, Drosophila Frizzled 2, Dm Fz2, DFz2, dFz2, Dfz2, DFz-2, FZ2, frizzled-2, frizzled2, Fz2, Dfrizzled2, CG9739, fz-2, D-Fz2, Dfrizzled[[2]], Dfz[[2]], Dfrz2, Frizzled2, D-frizzled2, dfz(2), D-fz2, dfz2, frz2, Frizzled 2" "IPR020067=Frizzled domain, IPR017981=GPCR, family 2-like, IPR000539=Frizzled protein, IPR015526=Frizzled/secreted frizzled-related protein" CG9739 16-Dec-15 2015_12 "ENSDARG00000025420(fzd8c),ENSDARG00000045444(fzd8a),ENSDARG00000038569(fzd8b)" WBGene00000478(cfz-2) "ENSXETG00000016383(FZD5),ENSXETG00000008812(FZD8)" "ENSMUSG00000036904(Fzd8),ENSMUSG00000045005(Fzd5)" "ENSG00000177283(FZD8),ENSG00000163251(FZD5)" " embryonic stage | stage 10 , embryonic stage | stage 9-17 , embryonic stage | stage 12-16 , embryonic stage | stage 8 , embryonic stage | stage 6 , embryonic stage | stage 13-17 , embryonic stage -- adult stage , embryonic stage | stage 17 " " procephalic neurogenic region

, embryonic central nervous system | presumptive

, visceral mesoderm

, posterior midgut proper primordium

,

segmentally repeated , organism | 10-70% egg length

, embryonic/larval hindgut

, embryonic/larval dorsal vessel

" " embryonic stage | stage 10 , embryonic stage | stage 12-16 , embryonic stage | stage 9-17 , embryonic stage | stage 17 , embryonic stage | stage 13-17 , larval stage | third instar " " posterior midgut proper primordium

, procephalic neurogenic region

, visceral mesoderm

, embryonic central nervous system | presumptive

, embryonic/larval dorsal vessel

, embryonic/larval hindgut

, bouton | subset

" "partially lethal - majority die,viable,sterile,small body,neuroanatomy defective,partially lethal,lethal,visible,decreased cell death,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,planar polarity defective" "ovary,axon & dorsal cluster neuron,lamina,eye photoreceptor cell,neuron,NMJ bouton,wing margin bristle,ectopic,RP2 motor neuron,embryonic epidermis,dorsal,dorsal denticle,wing,eye photoreceptor cell | P-stage,lymph gland derived hemocyte | third instar larval stage,embryonic/larval lymph gland | third instar larval stage,crystal cell | third instar larval stage,wing & macrochaeta69B,macrochaeta,wing sensillum,bouton,neuromuscular junctionC57,postsynaptic membraneC57,mitochondrion & boutonC57,t-bar,interfollicle cell,supernumerary,heat sensitive,chaeta | ectopic & wingbbg-C96,denticle row 1,wing margin,eye,ommatidium,morphogenetic furrow,presumptive embryonic salivary gland,neuromuscular junction | third instar larval stageMhc.PU,dorsal cluster neuron | adult stage,medulla | adult stage" DRSC10087 IE -2.47348023 0.15174713 1.560219484 0.298005816 -0.215672261 0.128005045 FBgn0264695 Mhc Myosin heavy chain http://flybase.net/reports/FBgn0264695.html "FBgn0086783, FBgn0002741, FBgn0010142, FBgn0021948, FBgn0020400, FBgn0028724, FBgn0028640" protein_coding_gene "0000146=microfilament motor activity, 0042803=protein homodimerization activity, 0005524=ATP binding, 0008307=structural constituent of muscle, 0030898=actin-dependent ATPase activity, 0042623=ATPase activity, coupled" "0050821=protein stabilization, 0040011=locomotion, 0060361=flight, 0031033=myosin filament organization, 0030241=skeletal muscle myosin thick filament assembly, 0007298=border follicle cell migration, 0030239=myofibril assembly, 0042692=muscle cell differentiation, 0007427=epithelial cell migration, open tracheal system, 0071689=muscle thin filament assembly, 0007517=muscle organ development, 0006936=muscle contraction, 0007527=adult somatic muscle development, 0045214=sarcomere organization" "0016459=myosin complex, 0031672=A band, 0030017=sarcomere, 0005859=muscle myosin complex, 0005703=polytene chromosome puff" "Shrunken thorax, Myosin rod protein, l(2)k10423, l(2)36Ae, muscle myosin II, Mhc36B, Sht, myosin, ifm(2)RU1, Dm II, myo-II heavy chain, myosin heavy chain, chr2L:16765388..16765564, Myosin Heavy Chain-PF, Mrp, Not-upheld, mhc, Myosin Heavy Chain, DroMII, ifm(2)RU2, myosin heavy-chain protein, MyHC, Samba, muscle myosin, FBgn0002741, chr2L:16781880..16782040, Indirect flight muscle (2) RU1, Stp, mMHC, muscle myosin II heavy chain, myosin heavy, Ifm(2)2, Stuckup, myosin heavy-chain, muscle myosin heavy chain, Nup, CG17927, beta-myosin heavy chain, DROMHC, Muscle myosin heavy chain, muscle Myosin II heavy chain, Muscle Myosin, l(2)M66, indirect flight muscle (2) RU2, chain, Myo, Bsh, heavy chain, Myosin, MRP, ifm(2)2, Shrunken-thorax, sarcomeric myosin heavy-chain, Ifm(2)RU1, DmMHC, muscle specific myosin II, MHC, muscle myosin-II, sMHC" "IPR004009=Myosin, N-terminal, SH3-like, IPR027417=P-loop containing nucleoside triphosphate hydrolase, IPR027401=Myosin-like IQ motif-containing domain, IPR001609=Myosin head, motor domain, IPR002928=Myosin tail, IPR000048=IQ motif, EF-hand binding site" CG17927 16-Dec-15 2015_12 "ENSDARG00000068743,ENSDARG00000045242(LOC100329670),ENSDARG00000071433(smyhc2),ENSDARG00000071435(LOC100329813),ENSDARG00000071430(smyhc1),ENSDARG00000015618,ENSDARG00000067600,ENSDARG00000001993(myhb),ENSDARG00000067597(zgc:66156),ENSDARG00000012944(myhz2),ENSDARG00000067990(myhz1.1),ENSDARG00000067995(myhz1.2),ENSDARG00000067997(ns:zf-e68),ENSDARG00000035438(myhc4),ENSDARG00000035437(LOC100149148),ENSDARG00000035322(si:ch211-209j10.4)" YHR023W(MYO1) "WBGene00006789(unc-54),WBGene00002348(let-75),WBGene00003514(myo-2),WBGene00003515(myo-3),WBGene00019064(myo-5)" "ENSXETG00000016248(BC075407.1),ENSXETG00000016267(),ENSXETG00000017821(myh8),ENSXETG00000011987(mhy6),ENSXETG00000014570(),ENSXETG00000016136(),ENSXETG00000023940(),ENSXETG00000007456(MYH7B)" "ENSMUSG00000053093(Myh7),ENSMUSG00000040752(Myh6),ENSMUSG00000056328(Myh1),ENSMUSG00000057003(Myh4),ENSMUSG00000055775(Myh8),ENSMUSG00000033196(Myh2),ENSMUSG00000020908(Myh3),ENSMUSG00000060180(Myh13),ENSMUSG00000074652(Myh7b)" "ENSG00000197616(MYH6),ENSG00000092054(MYH7),ENSG00000109061(MYH1),ENSG00000125414(MYH2),ENSG00000141048(MYH4),ENSG00000133020(MYH8),ENSG00000109063(MYH3),ENSG00000006788(MYH13),ENSG00000078814(MYH7B),ENSG00000144821(MYH15)" " embryonic stage | late && larval stage , pupal stage | late , adult stage , embryonic stage , adult stage | male , embryonic stage | stage 16 , pharate adult stage && adult stage , larval stage " " organism

, skeletal muscle of abdomen

, mesothoracic extracoxal depressor muscle 66

, proboscis muscle

, adult abdomen

, adult thorax

, adult esophageal muscle

, skeletal muscle of leg

, somatic muscle

, testis

, somatic muscle

{ e N* } , adult head

, visceral muscle

, indirect flight muscle

, basalar muscle 51

, intracoxal depressor muscle

, larval muscle system

, mesothoracic pleurosternal muscle

, larval somatic muscle

{ e Dl* } , skeletal muscle of head

, somatic mesoderm

, basalar muscle 52

, intracoxal levator muscle

, skeletal muscle of thorax

" adult stage | male testis

DRSC03367 E 0.507275638 0.380817739 1.78275102 -2.488034787 -0.731386506 1.074970336 FBgn0015919 caup caupolican http://flybase.net/reports/FBgn0015919.html FBgn0014195 protein_coding_gene "0003700=sequence-specific DNA binding transcription factor activity, 0043565=sequence-specific DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" "0006357=regulation of transcription from RNA polymerase II promoter, 0006909=phagocytosis, 0001745=compound eye morphogenesis, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0045317=equator specification, 0042693=muscle cell fate commitment, 0007474=imaginal disc-derived wing vein specification" 0005634=nucleus "iroquois-complex, Iro-C, iro-C, Iroquois, Cauplican, Iroquis complex, iroquois, iroquois gene complex, IroC, CG10605, Caup, IRO-C, iro, Iro, Caupolican" "IPR001356=Homeobox domain, IPR008422=Homeobox KN domain, IPR017970=Homeobox, conserved site, IPR009057=Homeodomain-like, IPR003893=Iroquois-class homeodomain protein" CG10605 16-Dec-15 2015_12 ENSDARG00000034420(irx6a) "ENSXETG00000002816(Q4LDQ3_XENTR),ENSXETG00000012653(irx2)" "ENSMUSG00000031737(Irx5),ENSMUSG00000031734(Irx3),ENSMUSG00000060969(Irx1),ENSMUSG00000001504(Irx2)" "ENSG00000177508(IRX3),ENSG00000170549(IRX1),ENSG00000176842(IRX5)" " larval stage | third instar , adult stage , embryonic stage | late , larval stage , embryonic stage -- adult stage , larval stage | second instar , embryonic stage | stage >=11 " " wing vein L5

, alula

, embryonic/larval proventriculus

, procephalic segment

, ventral nerve cord

, tegula

, wing vein L1

, wing vein L3

, mesothoracic pleurum

, imaginal disc

, dorsal metathoracic disc

, epidermis | lateral

" "visible,lethal,recessive,viable,female sterile,male sterile,planar polarity defective" "macrochaeta,microchaeta,mesothoracic segment,notopleural suture,scutellum,wing,macrochaeta & scutum,eye,vertical bristle,scutum & microchaeta | medial-537.4,ectopic,ommatidium,dorsal margin photoreceptor" FBgn0000611 exd extradenticle http://flybase.net/reports/FBgn0000611.html "FBgn0010248, FBgn0025242" protein_coding_gene "0043565=sequence-specific DNA binding, 0035326=enhancer binding, 0003713=transcription coactivator activity, 0003677=DNA binding, 0003705=RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, 0003700=sequence-specific DNA binding transcription factor activity, 0033613=activating transcription factor binding, 0005515=protein binding, 0046982=protein heterodimerization activity, 0008134=transcription factor binding" "0007438=oenocyte development, 0045944=positive regulation of transcription from RNA polymerase II promoter, 0007479=leg disc proximal/distal pattern formation, 0006357=regulation of transcription from RNA polymerase II promoter, 0000060=protein import into nucleus, translocation, 0007420=brain development, 0007525=somatic muscle development, 0042659=regulation of cell fate specification, 0001654=eye development, 0007432=salivary gland boundary specification, 0007422=peripheral nervous system development" "0005667=transcription factor complex, 0005737=cytoplasm, 0005634=nucleus" "DExd, Extradenticle, EXD, Pbx1, anon-fast-evolving-1H3, lincRNA.S9404, Exd, Pbx1-oncogene-like, td48, l(1)IV, Dpbx, anon-EST:fe1H3, unnamed, Dm-EXD, CG8933" "IPR005542=PBX, IPR009057=Homeodomain-like, IPR017970=Homeobox, conserved site, IPR001356=Homeobox domain" CG8933 16-Dec-15 2015_12 "ENSDARG00000013615(pbx3b),ENSDARG00000027695(zgc:158824),ENSDARG00000008145(pbx1a),ENSDARG00000020664(pbx3a),ENSDARG00000019717(LOC100332432)" WBGene00000443(ceh-20) "ENSXETG00000010464(PBX1),ENSXETG00000000502(PBX3),ENSXETG00000005223()" "ENSMUSG00000052534(Pbx1),ENSMUSG00000038718(Pbx3),ENSMUSG00000034673(Pbx2)" "ENSG00000185630(PBX1),ENSG00000167081(PBX3),ENSG00000204304(PBX2),ENSG00000206315,ENSG00000206247" " embryonic stage , embryonic stage | stage >11 , embryonic stage | stage 12 " " somatic mesoderm

{ + BX-C- } , embryonic central nervous system

,

gradient , abdomen

, visceral mesoderm | gradient

" "lethal,recessive,visible,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,pair rule phenotype,partially lethal - majority die,size defective" "adult abdominal segment 7,somatic clone,female genitalia,adult abdominal segment 6,arista,leg,proximal,leg sensillum,ectopic,male genitalia,adult abdominal segment 8,adult abdominal segment 9,adult head,cuticle,metathoracic ventral denticle belt,mesothoracic ventral denticle belt,prothoracic ventral denticle belt,prothoracic dorsal trichome,hypostomal sclerite,embryonic mesothoracic segment,ventral,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,mesothoracic tergum & macrochaeta | ectopic | somatic clone,scutellum & chaeta | somatic clone,embryonic/larval oenocyte,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,trochanter,femur,dorsal,posterior,embryonic head,embryonic thorax,embryonic gnathal segment,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,presumptive embryonic/larval peripheral nervous system,head segment,mandibular segment,dental sclerite,epipharyngeal sclerite,median tooth,lateral process,scutum,distal,eye,medial,metathoracic laterotergite,antenna,head,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,macrochaeta & scutum,third segment of antenna,proboscis,adult abdominal segment 1,adult abdominal segment 2,adult abdominal segment 3,adult abdominal segment 4,deutero/tritocerebral embryonic fiber tract founder cluster,subesophageal embryonic fiber tract founder cluster,supraesophageal embryonic fiber tract founder cluster,cervical connective,tritocerebral commissure,Bolwig nerve,Bolwig organ,embryonic/larval salivary gland,embryonic stomatogastric nervous system,optic lobe,precursor,embryonic abdominal segment,mesothoracic segment,metathoracic segment,abdominal segment 1,tarsal segment,unguis,ventral thoracic disc,tibia,mesothoracic tergum,flight muscle,extracoxal depressor muscle" FBgn0027598 cindr CIN85 and CD2AP orthologue http://flybase.net/reports/FBgn0027598.html "FBgn0039803, FBgn0051012" protein_coding_gene "0017124=SH3 domain binding, 0050839=cell adhesion molecule binding, 0005070=SH3/SH2 adaptor activity" "0043063=intercellular bridge organization, 0007298=border follicle cell migration, 0048260=positive regulation of receptor-mediated endocytosis, 0046331=lateral inhibition, 0007015=actin filament organization, 0048749=compound eye development, 0001745=compound eye morphogenesis, 0032465=regulation of cytokinesis" "0030496=midbody, 0045171=intercellular bridge, 0032154=cleavage furrow" "CD2AP and CIN85 orthologue, CG11316, Cindr, BcDNA:GH03163, CD2AP, CG1408, CIN85 and CD2AP orthologue, cindr, CG31012" IPR001452=SH3 domain CG31012 16-Dec-15 2015_12 ENSXETG00000006205(SH3KBP1) "planar polarity defective,lethal,viable,visible" "primary pigment cell,actin cytoskeletonGMR.PF, cindrdsRNA.PC.PD.UAS,inter-ommatidial precursor cell,cone cell,ommatidium,pigment cell,somatic clone,follicle cell,intercellular bridgeGR1, cindrdsRNA.PC.PD.UAS,border follicle cell,actin cytoskeletonGMR.PF, cindrdsRNA.UAS,secondary pigment cell,tertiary pigment cell,eye | pupal stage,macrochaeta,intercellular bridgeGR1, cindrdsRNA.UAS,chaeta,supernumerary" FBgn0264822 CR44030 http://flybase.net/reports/FBgn0264822.html non_protein_coding_gene CR44030 16-Dec-15 2015_12